{"text_format":"3","workbook":"xlsx","n_sheets":4,"sheets":["4 week samples","12 week samples","17 week samples","25 weeks samples"],"bounds":{"halvings":1},"cells_cut":148,"read":"whole","date_system":"1900"}

{"sheet":"4 week samples","index":0,"n_rows":16650,"n_cols":15,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["Gene ID","Gene Symbol","4_weeks_1 Read Count","4_weeks_2 Read Count","4_weeks_3 Read Count","4_weeks Average Read Count","KEGG Pathway Desc","KEGG Disease Desc","KEGG Module Desc","KEGG Reaction Desc","GO_C Desc","GO_F Desc","GO_P Desc","GeneBank Desc","UniProt Desc"]
[1,"'A1BG'",87,79,64,76.6666666666667,"04380///Osteoclast differentiation",{"$nulls":3},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0031093///platelet alpha granule lumen+++GO:1904813///ficolin-1-rich granule lumen+++GO:0034774///secretory granule lumen+++GO:0062023///collagen-containing extracellular matrix+++GO:0072562///blood microparticle","GO:0003674///molecular_function","GO:0002576///platelet degranulation+++GO:0043312///neutrophil degranulation+++GO:0008150///biological_process","alpha-1-B glycoprotein","[A1BG_HUMAN|Reviewed]RecName: Full=Alpha-1B-glycoprotein; AltName: Full=Alpha-1-B glycoprotein; Flags: Precursor;+++[M0R009_HUMAN|Unreviewed]SubName: Full=Alpha-1B-glycoprotein {ECO:0000313|Ensembl:ENSP00000470909}; Flags: Fragment;+++[V9HWD8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 163pA {ECO:0000313|EMBL:ACJ13639.1};"]
[10,"'NAT2'",3,0,2,1.66666666666667,"00983///Drug metabolism - other enzymes+++05204///Chemical carcinogenesis+++01100///Metabolic pathways+++00633///Nitrotoluene degradation+++00232///Caffeine metabolism+++01110///Biosynthesis of secondary metabolites+++01120///Microbial metabolism in diverse environments",null,null,"R11902///acetyl-CoA:hydrazine N-acetyltransferase   Acetyl-CoA + Hydrazine <=> CoA + Acetylhydrazine+++R07940///1,7-Dimethylxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil+++R08036///acetyl-CoA:2,4-diamino-6-nitrotoluene N-acetyltransferase   2,4-Diamino-6-nitrotoluene + Acetyl-CoA <=> 4-Acetamido-2-amino-6-nitrotoluene + CoA+++R08248///acetyl-CoA: isoniazid N-acetyltransferase   Acetyl-CoA + Isoniazid <=> CoA + N-Acetylisoniazid+++R08250///acetyl-CoA:acetylhydrazine N-acetyltransferase   Acetyl-CoA + Acetylhydrazine <=> CoA + N,N'-Diacetylhydrazine","GO:0005829///cytosol","GO:0004060///arylamine N-acetyltransferase activity","GO:0006805///xenobiotic metabolic process","N-acetyltransferase 2","[ARY2_HUMAN|Reviewed]RecName: Full=Arylamine N-acetyltransferase 2; EC=2.3.1.5; AltName: Full=Arylamide acetylase 2; AltName: Full=N-acetyltransferase type 2; Short=NAT-2; AltName: Full=Polymorphic arylamine N-acetyltransferase; Short=PNAT;+++[A4Z6T7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01136.1};"]
[100,"'ADA'",121,162,124,135.666666666667,"05340///Primary immunodeficiency+++01100///Metabolic pathways+++00230///Purine metabolism","H00092///T-B-Severe combined immunodeficiencies (SCIDs)",null,"R01560///Adenosine aminohydrolase   Adenosine + H2O <=> Inosine + Ammonia+++R02556///Deoxyadenosine aminohydrolase   Deoxyadenosine + H2O <=> Deoxyinosine + Ammonia","GO:0032839///dendrite cytoplasm+++GO:0030054///cell junction+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0060205///cytoplasmic vesicle lumen+++GO:0005764///lysosome+++GO:0005615///extracellular space+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004000///adenosine deaminase activity+++GO:0001883///purine nucleoside binding+++GO:0019239///deaminase activity","GO:0046061///dATP catabolic process+++GO:0042493///response to drug+++GO:0046111///xanthine biosynthetic process+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0043103///hypoxanthine salvage+++GO:0043066///negative regulation of apoptotic process+++GO:0001889///liver development+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0001701///in utero embryonic development+++GO:0032261///purine nucleotide salvage+++GO:0043101///purine-containing compound salvage+++GO:0030324///lung development+++GO:0002314///germinal center B cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0010460///positive regulation of heart rate+++GO:0050870///positive regulation of T cell activation+++GO:0033197///response to vitamin E+++GO:0001821///histamine secretion+++GO:0045580///regulation of T cell differentiation+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0042542///response to hydrogen peroxide+++GO:0060169///negative regulation of adenosine receptor signaling pathway+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007155///cell adhesion+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046101///hypoxanthine biosynthetic process+++GO:0048541///Peyer's patch development+++GO:0001890///placenta development+++GO:0048566///embryonic digestive tract development+++GO:0009117///nucleotide metabolic process+++GO:0060407///negative regulation of penile erection+++GO:0042110///T cell activation+++GO:0070256///negative regulation of mucus secretion+++GO:0042323///negative regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046103///inosine biosynthetic process+++GO:0002636///positive regulation of germinal center formation+++GO:0050728///negative regulation of inflammatory response+++GO:0048286///lung alveolus development+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0046085///adenosine metabolic process+++GO:0002686///negative regulation of leukocyte migration+++GO:0007568///aging+++GO:0043278///response to morphine+++GO:0045582///positive regulation of T cell differentiation+++GO:0001666///response to hypoxia+++GO:0001829///trophectodermal cell differentiation+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process","adenosine deaminase","[ADA_HUMAN|Reviewed]RecName: Full=Adenosine deaminase; EC=3.5.4.4 {ECO:0000269|PubMed:16670267, ECO:0000269|PubMed:23193172, ECO:0000269|PubMed:8452534}; AltName: Full=Adenosine aminohydrolase;+++[A0A0S2Z381_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 1 {ECO:0000313|EMBL:ALQ33350.1}; SubName: Full=Adenosine deaminase, isoform CRA_c {ECO:0000313|EMBL:EAW75906.1}; Flags: Fragment;+++[A0A0S2Z3B9_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 3 {ECO:0000313|EMBL:ALQ33352.1}; Flags: Fragment;+++[A0A0S2Z3T6_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 4 {ECO:0000313|EMBL:ALQ33353.1}; Flags: Fragment;+++[F5GWI4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 2 {ECO:0000313|EMBL:ALQ33351.1};+++[F5GXW0_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000440946};+++[F5GYD4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000446464};+++[Q16073_HUMAN|Unreviewed]SubName: Full=Mutant adenosine deaminase {ECO:0000313|EMBL:AAB28742.2}; Flags: Fragment;+++[X5D767_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform A {ECO:0000313|EMBL:AHW56400.1}; Flags: Fragment;"]
[1000,"'CDH2'",4184,3547,3893,3874.66666666667,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0005788///endoplasmic reticulum lumen+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005911///cell-cell junction+++GO:0016324///apical plasma membrane+++GO:0016342///catenin complex+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0045177///apical part of cell+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0005916///fascia adherens+++GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0042383///sarcolemma+++GO:0030864///cortical actin cytoskeleton+++GO:0044853///plasma membrane raft","GO:0008092///cytoskeletal protein binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding+++GO:0045294///alpha-catenin binding+++GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0060019///radial glial cell differentiation+++GO:0051146///striated muscle cell differentiation+++GO:0007416///synapse assembly+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0072659///protein localization to plasma membrane+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0034332///adherens junction organization+++GO:0048514///blood vessel morphogenesis+++GO:0043410///positive regulation of MAPK cascade+++GO:0060563///neuroepithelial cell differentiation+++GO:0021987///cerebral cortex development+++GO:0010001///glial cell differentiation+++GO:0048854///brain morphogenesis+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050770///regulation of axonogenesis+++GO:1902897///regulation of postsynaptic density protein 95 clustering+++GO:0043687///post-translational protein modification+++GO:0016477///cell migration+++GO:0097150///neuronal stem cell population maintenance+++GO:0048872///homeostasis of number of cells+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0009966///regulation of signal transduction+++GO:0098609///cell-cell adhesion+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0021537///telencephalon development+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0044267///cellular protein metabolic process","cadherin 2","[CADH2_HUMAN|Reviewed]RecName: Full=Cadherin-2; AltName: Full=CDw325; AltName: Full=Neural cadherin; Short=N-cadherin; AltName: CD_antigen=CD325; Flags: Precursor;+++[A0A024RC42_HUMAN|Unreviewed]SubName: Full=Cadherin 2, type 1, N-cadherin (Neuronal), isoform CRA_b {ECO:0000313|EMBL:EAX01241.1};+++[C9J126_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000412120}; Flags: Fragment;+++[C9J8J8_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000411360}; Flags: Fragment;+++[C9JMH2_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000414269}; Flags: Fragment;"]
[10000,"'AKT3'",1059,889.96,882,943.653333333333,"04973///Carbohydrate digestion and absorption+++04150///mTOR signaling pathway+++05211///Renal cell carcinoma+++05230///Central carbon metabolism in cancer+++05221///Acute myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++05145///Toxoplasmosis+++04910///Insulin signaling pathway+++05218///Melanoma+++05166///HTLV-I infection+++04261///Adrenergic signaling in cardiomyocytes+++05164///Influenza A+++04668///TNF signaling pathway+++05210///Colorectal cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05165///Human papillomavirus infection+++04611///Platelet activation+++04722///Neurotrophin signaling pathway+++04071///Sphingolipid signaling pathway+++04212///Longevity regulating pathway - worm+++04371///Apelin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04664///Fc epsilon RI signaling pathway+++05163///Human cytomegalovirus infection+++04024///cAMP signaling pathway+++05226///Gastric cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04550///Signaling pathways regulating pluripotency of stem cells+++04068///FoxO signaling pathway+++04062///Chemokine signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04660///T cell receptor signaling pathway+++04728///Dopaminergic synapse+++04213///Longevity regulating pathway - multiple species+++05160///Hepatitis C+++01524///Platinum drug resistance+++05222///Small cell lung cancer+++04630///Jak-STAT signaling pathway+++04510///Focal adhesion+++05200///Pathways in cancer+++04218///Cellular senescence+++04662///B cell receptor signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04917///Prolactin signaling pathway+++05225///Hepatocellular carcinoma+++05214///Glioma+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++05169///Epstein-Barr virus infection+++05213///Endometrial cancer+++04931///Insulin resistance+++04920///Adipocytokine signaling pathway+++04915///Estrogen signaling pathway+++05161///Hepatitis B+++04066///HIF-1 signaling pathway+++04625///C-type lectin receptor signaling pathway+++05231///Choline metabolism in cancer+++04014///Ras signaling pathway+++05162///Measles+++04151///PI3K-Akt signaling pathway+++04926///Relaxin signaling pathway+++04012///ErbB signaling pathway+++04922///Glucagon signaling pathway+++05224///Breast cancer+++04211///Longevity regulating pathway+++05215///Prostate cancer+++04152///AMPK signaling pathway+++04914///Progesterone-mediated oocyte maturation+++05212///Pancreatic cancer+++04022///cGMP-PKG signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05220///Chronic myeloid leukemia+++04620///Toll-like receptor signaling pathway+++04725///Cholinergic synapse+++04072///Phospholipase D signaling pathway+++04210///Apoptosis+++05152///Tuberculosis+++04140///Autophagy - animal+++05205///Proteoglycans in cancer+++05223///Non-small cell lung cancer+++04370///VEGF signaling pathway+++04919///Thyroid hormone signaling pathway+++04380///Osteoclast differentiation","H01556///Meningioma+++H01222///Cowden syndrome+++H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01909///Hypoinsulinemic hypoglycemia with hemihypertrophy (HIHGHH)+++H00420///Familial partial lipodystrophy (FPL)+++H01649///Schizophrenia+++H00027///Ovarian cancer","M00676///PI3K-Akt signaling",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0035556///intracellular signal transduction+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032008///positive regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0045766///positive regulation of angiogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0045793///positive regulation of cell size+++GO:0000002///mitochondrial genome maintenance+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0048854///brain morphogenesis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0006468///protein phosphorylation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007165///signal transduction+++GO:1905653///positive regulation of artery morphogenesis","AKT serine/threonine kinase 3","[AKT3_HUMAN|Reviewed]RecName: Full=RAC-gamma serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Protein kinase Akt-3; AltName: Full=Protein kinase B gamma; Short=PKB gamma; AltName: Full=RAC-PK-gamma; AltName: Full=STK-2;+++[F8VS91_HUMAN|Unreviewed]SubName: Full=RAC-gamma serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000447820}; Flags: Fragment;+++[Q56A86_HUMAN|Unreviewed]SubName: Full=AKT3 protein {ECO:0000313|EMBL:AAH20479.1}; Flags: Fragment;"]
[10001,"'MED6'",212.5,191.5,208,204,{"$nulls":4},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0000151///ubiquitin ligase complex+++GO:0070847///core mediator complex+++GO:0005654///nucleoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0003712///transcription coregulator activity+++GO:0008134///transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001128///RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance+++GO:0016567///protein ubiquitination","mediator complex subunit 6","[MED6_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6; AltName: Full=Activator-recruited cofactor 33 kDa component; Short=ARC33; AltName: Full=Mediator complex subunit 6; Short=hMed6; AltName: Full=Renal carcinoma antigen NY-REN-28;+++[A0A087WYL7_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};+++[B4DTY4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|RuleBase:RU364143}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|RuleBase:RU364143};+++[G3V4A5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};"]
[10003,"'NAALAD2'",121,170,166,152.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0008236///serine-type peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0016805///dipeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity","GO:0006508///proteolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0042135///neurotransmitter catabolic process+++GO:0008152///metabolic process","N-acetylated alpha-linked acidic dipeptidase 2","[NALD2_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[E9PII2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000431989}; Flags: Fragment;+++[E9PJ53_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435670}; Flags: Fragment;+++[E9PJV2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000433710};+++[E9PKX5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435249};+++[J3KNJ3_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000320083};+++[L8EAF7_HUMAN|Unreviewed]SubName: Full=Alternative protein NAALAD2 {ECO:0000313|EMBL:CCQ43323.1};+++[Q4G181_HUMAN|Unreviewed]SubName: Full=NAALAD2 protein {ECO:0000313|EMBL:AAH27594.1};"]
[100033411,"'DUXB'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding","GO:0006355///regulation of transcription, DNA-templated","double homeobox B","[A0A1W2PPF3_HUMAN|Unreviewed]SubName: Full=Double homeobox B {ECO:0000313|Ensembl:ENSP00000491301};"]
[100037417,"'DDTL'",28.95,33.65,28.86,30.4866666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0016829///lyase activity",null,"D-dopachrome tautomerase like","[DDTL_HUMAN|Reviewed]RecName: Full=D-dopachrome decarboxylase-like protein; EC=4.1.1.-; AltName: Full=D-dopachrome tautomerase-like protein;+++[A0A0F7RPW6_HUMAN|Unreviewed]SubName: Full=D-dopachrome tautomerase 2 {ECO:0000313|EMBL:CCP37992.1};+++[B5MC82_HUMAN|Unreviewed]SubName: Full=D-dopachrome decarboxylase {ECO:0000313|Ensembl:ENSP00000384866};"]
[10004,"'NAALADL1'",39,44,46,43,{"$nulls":4},"GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004180///carboxypeptidase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity","GO:0008152///metabolic process+++GO:0006508///proteolysis","N-acetylated alpha-linked acidic dipeptidase like 1","[NALDL_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein; Short=NAALADase L; EC=3.4.17.21; AltName: Full=100 kDa ileum brush border membrane protein; Short=I100; AltName: Full=Ileal dipeptidylpeptidase;+++[C9JFW8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000349045};+++[E9PII9_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431977};+++[E9PIU1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433892}; Flags: Fragment;+++[E9PJQ1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435549}; Flags: Fragment;+++[E9PKG8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433538}; Flags: Fragment;+++[E9PKR0_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431513};+++[E9PKW7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435267}; Flags: Fragment;+++[E9PLR8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431322}; Flags: Fragment;+++[E9PRC7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434233}; Flags: Fragment;+++[H0YDS5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434225}; Flags: Fragment;+++[H0YEI8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435917}; Flags: Fragment;"]
[100049587,"'SIGLEC14'",0,2,1,1,{"$nulls":4},"GO:0101003///ficolin-1-rich granule membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane","GO:0030246///carbohydrate binding","GO:0043312///neutrophil degranulation+++GO:0007155///cell adhesion+++GO:0045087///innate immune response","sialic acid binding Ig like lectin 14","[SIG14_HUMAN|Reviewed]RecName: Full=Sialic acid-binding Ig-like lectin 14; Short=Siglec-14; Flags: Precursor;"]
[10005,"'ACOT8'",323,342,304,323,"00120///Primary bile acid biosynthesis+++01100///Metabolic pathways+++04146///Peroxisome",null,"M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R03974///chenodeoxycholoyl-CoA hydrolase   Chenodeoxycholate + CoA <=> Chenodeoxycholoyl-CoA + H2O+++R07296///choloyl-CoA hydrolase   Choloyl-CoA + H2O <=> Cholic acid + CoA","GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol","GO:0052815///medium-chain acyl-CoA hydrolase activity+++GO:0005102///signaling receptor binding+++GO:0052816///long-chain acyl-CoA hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0033882///choloyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0003986///acetyl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016289///CoA hydrolase activity","GO:0043649///dicarboxylic acid catabolic process+++GO:0007031///peroxisome organization+++GO:0045225///negative regulation of CD4 biosynthetic process+++GO:0016032///viral process+++GO:0006637///acyl-CoA metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0016559///peroxisome fission+++GO:0036109///alpha-linolenic acid metabolic process","acyl-CoA thioesterase 8","[ACOT8_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A thioesterase 8; Short=Acyl-CoA thioesterase 8; EC=3.1.2.27 {ECO:0000269|PubMed:15194431, ECO:0000269|PubMed:9299485}; AltName: Full=Choloyl-coenzyme A thioesterase; AltName: Full=HIV-Nef-associated acyl-CoA thioesterase; AltName: Full=PTE-2; AltName: Full=Peroxisomal acyl-coenzyme A thioester hydrolase 1; Short=PTE-1; AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase 1; AltName: Full=Thioesterase II; Short=hACTE-III; Short=hACTEIII; Short=hTE;+++[E9PIS4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000433923};+++[E9PJN0_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435581};+++[E9PMC4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000431175};+++[E9PRD4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000434216};+++[F6VBM3_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435115};+++[H0Y698_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000403862}; Flags: Fragment;+++[H7C5A7_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000419403}; Flags: Fragment;+++[Q6FHI2_HUMAN|Unreviewed]SubName: Full=PTE1 protein {ECO:0000313|EMBL:CAG46570.1};+++[Q9BR14_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000416217}; Flags: Fragment;"]
[10006,"'ABI1'",1981,1867,1774,1874,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0005783///endoplasmic reticulum+++GO:0031252///cell leading edge+++GO:0005634///nucleus+++GO:0031209///SCAR complex+++GO:0014069///postsynaptic density+++GO:0030426///growth cone+++GO:0032433///filopodium tip+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0030175///filopodium+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005856///cytoskeleton","GO:0030296///protein tyrosine kinase activator activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0017124///SH3 domain binding+++GO:0045296///cadherin binding","GO:0048813///dendrite morphogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0072673///lamellipodium morphogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0016032///viral process+++GO:0035855///megakaryocyte development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001756///somitogenesis+++GO:0008154///actin polymerization or depolymerization","abl interactor 1","[ABI1_HUMAN|Reviewed]RecName: Full=Abl interactor 1; AltName: Full=Abelson interactor 1; Short=Abi-1; AltName: Full=Abl-binding protein 4; Short=AblBP4; AltName: Full=Eps8 SH3 domain-binding protein; Short=Eps8-binding protein; AltName: Full=Nap1-binding protein; Short=Nap1BP; AltName: Full=Spectrin SH3 domain-binding protein 1; AltName: Full=e3B1;+++[A0A0A0MRT6_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000365330};+++[B6VEX3_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 41 {ECO:0000313|EMBL:ACJ12783.1};+++[B6VEX4_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000439646}; SubName: Full=Abl-interactor 1 variant 21 {ECO:0000313|EMBL:ACJ12784.1};+++[B6VEX5_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 72 {ECO:0000313|EMBL:ACJ12785.1};+++[L8EC66_HUMAN|Unreviewed]SubName: Full=Alternative protein ABI1 {ECO:0000313|EMBL:CCQ43032.1};"]
[10007,"'GNPDA1'",1022,1197,1056,1091.66666666667,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways",null,null,"R00765///D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); D-glucosamine-6-phosphate   D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia","GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0043209///myelin sheath+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0060170///ciliary membrane+++GO:0034774///secretory granule lumen","GO:0016853///isomerase activity+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0004347///glucose-6-phosphate isomerase activity+++GO:0016787///hydrolase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0048029///monosaccharide binding+++GO:0042802///identical protein binding+++GO:0004342///glucosamine-6-phosphate deaminase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0016866///intramolecular transferase activity+++GO:0008134///transcription factor binding+++GO:0004672///protein kinase activity+++GO:0004707///MAP kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding","GO:0051156///glucose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0006094///gluconeogenesis+++GO:0016310///phosphorylation+++GO:0033574///response to testosterone+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0006043///glucosamine catabolic process+++GO:0032570///response to progesterone+++GO:0035556///intracellular signal transduction+++GO:0001707///mesoderm formation+++GO:0007338///single fertilization+++GO:0016055///Wnt signaling pathway+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0035902///response to immobilization stress+++GO:0042501///serine phosphorylation of STAT protein+++GO:0010595///positive regulation of endothelial cell migration+++GO:0035994///response to muscle stretch+++GO:0061621///canonical glycolysis+++GO:0043312///neutrophil degranulation+++GO:0005975///carbohydrate metabolic process+++GO:0046777///protein autophosphorylation+++GO:0007599///hemostasis+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0010469///regulation of signaling receptor activity+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0000165///MAPK cascade+++GO:0050821///protein stabilization+++GO:0001701///in utero embryonic development+++GO:0046185///aldehyde catabolic process+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0046686///response to cadmium ion+++GO:0042593///glucose homeostasis+++GO:0019242///methylglyoxal biosynthetic process+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0043278///response to morphine+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006959///humoral immune response+++GO:0032355///response to estradiol+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010468///regulation of gene expression+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0007611///learning or memory+++GO:0006468///protein phosphorylation+++GO:0034101///erythrocyte homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006046///N-acetylglucosamine catabolic process","glucosamine-6-phosphate deaminase 1","[GNPI1_HUMAN|Reviewed]RecName: Full=Glucosamine-6-phosphate isomerase 1; EC=3.5.99.6; AltName: Full=Glucosamine-6-phosphate deaminase 1; Short=GNPDA 1; Short=GlcN6P deaminase 1; AltName: Full=Oscillin;+++[A0A0A0MTS2_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0G2JLI6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464798}; Flags: Fragment;+++[A0A0J9YX90_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488295}; Flags: Fragment;+++[A0A0J9YXH9_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488409}; Flags: Fragment;+++[A0A0J9YXM3_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488465}; Flags: Fragment;+++[A0A0J9YXP8_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYH3_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYI8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488871}; Flags: Fragment;+++[A0A2R8Y6C7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000495129};+++[A0A2R8YF08_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000496041}; Flags: Fragment;+++[D6R917_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000422173}; Flags: Fragment;+++[D6R9P4_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197};+++[D6RAY7_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RB13_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFF8_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFK5_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000426583}; Flags: Fragment;+++[K7EIL4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464797}; Flags: Fragment;+++[K7ELR7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466191}; Flags: Fragment;+++[K7ENA0_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466851}; Flags: Fragment;+++[K7EP41_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467221}; Flags: Fragment;+++[K7EPY4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467590}; Flags: Fragment;+++[K7EQ48_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[K7ERC6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468201}; Flags: Fragment;+++[K7ERK8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468298}; Flags: Fragment;"]
[10008,"'KCNE3'",66.89,97,53,72.2966666666667,"04974///Protein digestion and absorption","H00728///Brugada syndrome (BRS)+++H00215///Periodic paralysis",null,null,"GO:0031982///vesicle+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0008076///voltage-gated potassium channel complex+++GO:0005886///plasma membrane+++GO:0043204///perikaryon+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0032809///neuronal cell body membrane","GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005515///protein binding+++GO:0005244///voltage-gated ion channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity","GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:0006813///potassium ion transport+++GO:1905025///negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0006811///ion transport+++GO:0043266///regulation of potassium ion transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:1902260///negative regulation of delayed rectifier potassium channel activity","potassium voltage-gated channel subfamily E regulatory subunit 3","[KCNE3_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 3; AltName: Full=MinK-related peptide 2; AltName: Full=Minimum potassium ion channel-related peptide 2; AltName: Full=Potassium channel subunit beta MiRP2;+++[E9PJQ7_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000435539}; Flags: Fragment;+++[E9PJV9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000433697}; Flags: Fragment;+++[E9PN03_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000434890}; Flags: Fragment;+++[Q2N1I1_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3a {ECO:0000313|EMBL:ABB00304.1}; SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3b {ECO:0000313|EMBL:ABB00305.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000431739}; Flags: Fragment;+++[Q6IAE6_HUMAN|Unreviewed]SubName: Full=KCNE3 protein {ECO:0000313|EMBL:CAG33490.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|EMBL:ABQ01240.1}; SubName: Full=Potassium voltage-gated channel, Isk-related family, member 3 {ECO:0000313|EMBL:AAI10613.1}; SubName: Full=cDNA, FLJ92142, Homo sapiens potassium voltage-gated channel, Isk-related family,member 3 (KCNE3), mRNA {ECO:0000313|EMBL:BAG34817.1};"]
[10009,"'ZBTB33'",498,366,418,427.333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0003677///DNA binding+++GO:0008327///methyl-CpG binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035556///intracellular signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway","zinc finger and BTB domain containing 33","[KAISO_HUMAN|Reviewed]RecName: Full=Transcriptional regulator Kaiso; AltName: Full=Zinc finger and BTB domain-containing protein 33;+++[L8E7W8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZBTB33 {ECO:0000313|EMBL:CCQ43375.1};"]
[1001,"'CDH3'",6440,7038,6421,6633,"04514///Cell adhesion molecules (CAMs)","H00785///Congenital hypotrichosis with juvenile macular dystrophy+++H00639///Ectodermal dysplasia, ectrodactyly, and macular dystrophy (EEM syndrome)",null,null,"GO:0005913///cell-cell adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0098794///postsynapse+++GO:0005802///trans-Golgi network+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0030027///lamellipodium+++GO:0016328///lateral plasma membrane+++GO:0016600///flotillin complex+++GO:0005768///endosome+++GO:0043296///apical junction complex+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane","GO:0030506///ankyrin binding+++GO:0042802///identical protein binding+++GO:0032794///GTPase activating protein binding+++GO:0045295///gamma-catenin binding+++GO:0005509///calcium ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0045296///cadherin binding+++GO:0008013///beta-catenin binding","GO:0035635///entry of bacterium into host cell+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0072659///protein localization to plasma membrane+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0009636///response to toxic substance+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0022405///hair cycle process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0051796///negative regulation of timing of catagen+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0098609///cell-cell adhesion+++GO:0071681///cellular response to indole-3-methanol+++GO:0031424///keratinization+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0010628///positive regulation of gene expression+++GO:0001895///retina homeostasis+++GO:0042060///wound healing+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0071285///cellular response to lithium ion+++GO:1902910///positive regulation of melanosome transport+++GO:0031175///neuron projection development+++GO:0007601///visual perception+++GO:0007155///cell adhesion","cadherin 3","[CADH3_HUMAN|Reviewed]RecName: Full=Cadherin-3; AltName: Full=Placental cadherin; Short=P-cadherin; Flags: Precursor;+++[B4DLF0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50795, highly similar to Cadherin-3 {ECO:0000313|EMBL:BAG59512.1};"]
[10010,"'TANK'",312,344,272,309.333333333333,"04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway",{"$nulls":3},"GO:0035631///CD40 receptor complex+++GO:0097057///TRAF2-GSTP1 complex+++GO:0005654///nucleoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0045121///membrane raft+++GO:1990604///IRE1-TRAF2-ASK1 complex+++GO:0012506///vesicle membrane+++GO:0000151///ubiquitin ligase complex+++GO:0005938///cell cortex+++GO:1990597///AIP1-IRE1 complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex","GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0019899///enzyme binding+++GO:0046625///sphingolipid binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005174///CD40 receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035800///deubiquitinase activator activity+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0031996///thioesterase binding+++GO:0008289///lipid binding","GO:0070207///protein homotrimerization+++GO:0051291///protein heterooligomerization+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:0016579///protein deubiquitination+++GO:0007165///signal transduction+++GO:0006915///apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:2000158///positive regulation of ubiquitin-specific protease activity+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016032///viral process+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0032743///positive regulation of interleukin-2 production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0065003///protein-containing complex assembly+++GO:0070534///protein K63-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0071479///cellular response to ionizing radiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0090073///positive regulation of protein homodimerization activity+++GO:0071550///death-inducing signaling complex assembly+++GO:0043507///positive regulation of JUN kinase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1901215///negative regulation of neuron death+++GO:0051865///protein autoubiquitination+++GO:0097300///programmed necrotic cell death+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0034976///response to endoplasmic reticulum stress+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0051023///regulation of immunoglobulin secretion+++GO:0071347///cellular response to interleukin-1+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0046328///regulation of JNK cascade+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0006508///proteolysis+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030163///protein catabolic process+++GO:0034622///cellular protein-containing complex assembly+++GO:0071356///cellular response to tumor necrosis factor+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0034351///negative regulation of glial cell apoptotic process","TRAF family member associated NFKB activator","[TANK_HUMAN|Reviewed]RecName: Full=TRAF family member-associated NF-kappa-B activator; AltName: Full=TRAF-interacting protein; Short=I-TRAF;+++[B1AMX7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000405860}; Flags: Fragment;+++[B1AMX8_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000406524}; Flags: Fragment;+++[B1AMY1_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000397653}; Flags: Fragment;+++[B2R7S3_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93580, highly similar to Homo sapiens TRAF family member-associated NFKB activator (TANK), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG35920.1};+++[E5KBQ3_HUMAN|Unreviewed]SubName: Full=TRAF2 {ECO:0000313|EMBL:ADQ89802.1};+++[E7EM55_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412622};+++[E7EMT6_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000392776}; Flags: Fragment;+++[E7ENY2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000411041}; Flags: Fragment;+++[E7EQA9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000385487};+++[E7ERM9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000388930};+++[E7EV32_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000398157}; Flags: Fragment;+++[E7EVA2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384492};+++[E7EW82_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384235};+++[E7EWR8_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000399934}; Flags: Fragment;+++[E9PEK1_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000410259};+++[H7BZ28_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000387439}; Flags: Fragment;+++[H7C3L4_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412556}; Flags: Fragment;+++[Q4ZG76_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAX88939.1}; Flags: Fragment;+++[Q53TI5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAY14785.1}; Flags: Fragment;+++[Q6NW12_HUMAN|Unreviewed]SubName: Full=TANK protein {ECO:0000313|EMBL:AAH67779.1};"]
[100101267,"'POM121C'",3232.43,3837.81,3546.31,3538.85,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005515///protein binding+++GO:0035804///structural constituent of egg coat+++GO:0017056///structural constituent of nuclear pore+++GO:0003676///nucleic acid binding+++GO:0008139///nuclear localization sequence binding","GO:0007339///binding of sperm to zona pellucida+++GO:0035803///egg coat formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016032///viral process+++GO:0051028///mRNA transport+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus","POM121 transmembrane nucleoporin C","[P121C_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[A1L4L9_HUMAN|Unreviewed]SubName: Full=POM121C protein {ECO:0000313|EMBL:AAI30588.1};+++[A8MY32_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000381415}; Flags: Fragment;+++[B4DDR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56876, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG56826.1};+++[B4DET5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG57196.1};+++[C9JFL1_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000410033}; Flags: Fragment;"]
[100101467,"'ZSCAN30'",235,214,201,216.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated","zinc finger and SCAN domain containing 30","[ZSC30_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 30; AltName: Full=ZNF-WYM; AltName: Full=Zinc finger protein 397 opposite strand; AltName: Full=Zinc finger protein 397OS;+++[A0A0C4DGV0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000480152};+++[A0A1W2PP20_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000491237};+++[C9JCM2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000465046};+++[K7EPB0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000467308}; Flags: Fragment;+++[K7ERA9_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000468180}; Flags: Fragment;+++[M0QZC3_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470443};+++[M0QZP2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470677}; Flags: Fragment;+++[M0R1Y0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000472179};"]
[10011,"'SRA1'",476,483,456,471.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge","GO:0003713///transcription coactivator activity+++GO:0002153///steroid receptor RNA activator RNA binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:2000273///positive regulation of signaling receptor activity+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0006351///transcription, DNA-templated+++GO:0071391///cellular response to estrogen stimulus","steroid receptor RNA activator 1","[SRA1_HUMAN|Reviewed]RecName: Full=Steroid receptor RNA activator 1; AltName: Full=Steroid receptor RNA activator protein; Short=SRAP;"]
[100113407,"'TMEM170B'",119,126,114,119.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway","transmembrane protein 170B","[T170B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 170B;"]
[100125288,"'ZGLP1'",24,39,43,35.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0048599///oocyte development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis","zinc finger, GATA-like protein 1","[ZGLP1_HUMAN|Reviewed]RecName: Full=GATA-type zinc finger protein 1; AltName: Full=GATA-like protein 1; Short=GLP-1;+++[B5MCP8_HUMAN|Unreviewed]SubName: Full=GATA-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000385403};"]
[100127983,"'C8orf88'",344,315,269,309.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0008190///eukaryotic initiation factor 4E binding","GO:0045947///negative regulation of translational initiation","chromosome 8 open reading frame 88","[CH088_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C8orf88;"]
[100128071,"'FAM229A'",49,57,55,53.6666666666667,{"$nulls":7},"family with sequence similarity 229 member A","[F229A_HUMAN|Reviewed]RecName: Full=Protein FAM229A;+++[H3BMD6_HUMAN|Unreviewed]SubName: Full=Protein FAM229A {ECO:0000313|Ensembl:ENSP00000454338}; Flags: Fragment;"]
[100128108,"'LOC100128108'",13,14,16,14.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"putative ubiquitin-conjugating enzyme E2Q2-like protein","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;+++[UB2Q2_BOVIN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_HUMAN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_MOUSE|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_RABIT|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-conjugating enzyme UBCi; AltName: Full=Ubiquitin-protein ligase Q2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100128242,"'LOC100128242'",10,10.4,13,11.1333333333333,{"$nulls":7},"uncharacterized LOC100128242","[A0A1B0GVV0_HUMAN|diamond]SubName: Full=GRAM domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000490665};+++[A0A2I3SSV7_PANTR|diamond]SubName: Full=GRAM domain containing 1B {ECO:0000313|Ensembl:ENSPTRP00000080022};+++[A0A2J8N1X4_PANTR|diamond]SubName: Full=GRAMD1B isoform 18 {ECO:0000313|EMBL:PNI65769.1};+++[A0A2J8X087_PONAB|diamond]SubName: Full=GRAMD1B isoform 17 {ECO:0000313|EMBL:PNJ75447.1};+++[A0A2R9B6E3_PANPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000024636};"]
[100128553,"'CTAGE4'",34.65,26.42,36.44,32.5033333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0042954///lipoprotein transporter activity","GO:0042953///lipoprotein transport+++GO:0008150///biological_process+++GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion","CTAGE family member 4","[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[A0A2R8Y569_HUMAN|Unreviewed]SubName: Full=cTAGE family member 4 {ECO:0000313|Ensembl:ENSP00000494570};"]
[100128569,"'C19orf71'",2,0,4,2,{"$nulls":7},"chromosome 19 open reading frame 71","[CS071_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf71;"]
[100128731,"'OST4'",1209,1028,1112,1116.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0015631///tubulin binding+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding","GO:0018279///protein N-linked glycosylation via asparagine+++GO:0006486///protein glycosylation","oligosaccharyltransferase complex subunit 4, non-catalytic","[OST4_HUMAN|Reviewed]RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4;"]
[100128927,"'ZBTB42'",82,84,83,83,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0007517///muscle organ development+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 42","[ZBT42_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 42;"]
[100129128,"'KHDC1L'",0,1,2,1,{"$nulls":5},"GO:0003723///RNA binding",null,"KH domain containing 1 like","[KHDCL_HUMAN|Reviewed]RecName: Full=Putative KHDC1-like protein;"]
[100129250,"'SMIM27'",43,21,21,28.3333333333333,"05016///Huntington's disease+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++05012///Parkinson's disease+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)",null,"M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly","small integral membrane protein 27","[SIM27_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 27 {ECO:0000305}; AltName: Full=TOPORS antisense RNA 1 {ECO:0000305};+++[A0A1B0GV65_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490387};+++[A0A1B0GW09_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490727}; Flags: Fragment;+++[A0A1W2PRY6_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000492552}; Flags: Fragment;+++[A0A286YEC1_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000414891};+++[A0A2R8Y3B0_HUMAN|Unreviewed]SubName: Full=HCG1811779, isoform CRA_a {ECO:0000313|EMBL:EAW58544.1}; SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000493510};"]
[100129361,"'SMIM10L1'",611,579,550,580,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"small integral membrane protein 10 like 1","[SIML1_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 1 {ECO:0000305};"]
[100129396,"'FAM106CP'",0,3,1.38,1.46,{"$nulls":7},"family with sequence similarity 106 member C, pseudogene","[F106C_HUMAN|Reviewed]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;"]
[100129480,"'MKRN2OS'",4.04,2.46,3,3.16666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"MKRN2 opposite strand","[MKROS_HUMAN|Reviewed]RecName: Full=MKRN2 opposite strand protein; AltName: Full=MKRN2 antisense RNA 1; AltName: Full=MKRN2 antisense gene protein 1;+++[H3BSJ0_HUMAN|Unreviewed]SubName: Full=MKRN2 opposite strand protein {ECO:0000313|Ensembl:ENSP00000456723};"]
[100129484,"'LOC100129484'",10,16,10,12,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100129484","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100129528,"'MUC8'",3,1,1,1.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component",null,"GO:0008150///biological_process","mucin 8","[Q12964_HUMAN|Unreviewed]SubName: Full=Mucin {ECO:0000313|EMBL:AAA58346.1}; Flags: Fragment;"]
[100129543,"'ZNF730'",26,39,39,34.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 730","[ZN730_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 730;+++[M0QYG2_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469805}; Flags: Fragment;+++[M0QYI4_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469853};"]
[100129583,"'FAM47E'",8.24,6,2.32,5.52,{"$nulls":4},"GO:0005737///cytoplasm","GO:0003674///molecular_function","GO:0008150///biological_process","family with sequence similarity 47 member E","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[A0A1B0GTQ8_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000489801};+++[A0A1B0GUL4_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000490159};+++[D6RBT2_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000422559}; Flags: Fragment;+++[U3KQR7_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000476166}; Flags: Fragment;"]
[100129792,"'CCDC152'",59,51,56,55.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031089///platelet dense granule lumen+++GO:0005576///extracellular region","GO:0008430///selenium binding","GO:0019953///sexual reproduction+++GO:0001887///selenium compound metabolic process+++GO:0007626///locomotory behavior+++GO:0002576///platelet degranulation+++GO:0009791///post-embryonic development+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0040008///regulation of growth","coiled-coil domain containing 152","[CC152_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 152;+++[A0A024R043_HUMAN|Unreviewed]SubName: Full=HCG2006161, isoform CRA_a {ECO:0000313|EMBL:EAW56025.1};+++[L0R835_HUMAN|Unreviewed]SubName: Full=Alternative protein CCDC152 {ECO:0000313|EMBL:CCO13701.1};"]
[100129842,"'ZNF737'",211.13,251,245.23,235.786666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 737","[ZN737_HUMAN|Reviewed]RecName: Full=Zinc finger protein 737; AltName: Full=Zinc finger protein 102;+++[M0QZS4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000470737};+++[M0R1D1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471784}; Flags: Fragment;+++[M0R1M3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471973};+++[M0R1M8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471995}; Flags: Fragment;"]
[100129924,"'TMEM269'",2,1,0,1,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 269","[TM269_HUMAN|Reviewed]RecName: Full=Transmembrane protein 269 {ECO:0000312|HGNC:HGNC:52381};+++[A0A1B0GUR4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 269 {ECO:0000313|Ensembl:ENSP00000490213};"]
[100129940,"'LOC100129940'",4,6,6,5.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030686///90S preribosome","GO:0043236///laminin binding+++GO:0043022///ribosome binding+++GO:0003723///RNA binding+++GO:0005055///laminin receptor activity+++GO:0001618///virus receptor activity+++GO:0003735///structural constituent of ribosome","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000028///ribosomal small subunit assembly+++GO:0007155///cell adhesion+++GO:0006412///translation+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006413///translational initiation+++GO:0000461///endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006407///rRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","uncharacterized LOC100129940","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RSSA_BOVIN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Protein C10;+++[RSSA_CHLAE|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_HUMAN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Colon carcinoma laminin-binding protein; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Multidrug resistance-associated protein MGr1-Ag; AltName: Full=NEM/1CHD4; AltName: Full=Small ribosomal subunit protein uS2 {ECO:0000303|PubMed:24524803};+++[RSSA_PIG|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_SHEEP|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10013,"'HDAC6'",1241,1329,1140,1236.66666666667,"05034///Alcoholism+++05203///Viral carcinogenesis+++05165///Human papillomavirus infection",{"$nulls":3},"GO:0016235///aggresome+++GO:0005874///microtubule+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm+++GO:0016234///inclusion body+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0030286///dynein complex+++GO:0005654///nucleoplasm+++GO:0005771///multivesicular body+++GO:0031252///cell leading edge+++GO:0005875///microtubule associated complex+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005881///cytoplasmic microtubule+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005901///caveola+++GO:0044297///cell body+++GO:0043204///perikaryon+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0008013///beta-catenin binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0048156///tau protein binding+++GO:0043130///ubiquitin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004407///histone deacetylase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0070840///dynein complex binding+++GO:0003779///actin binding+++GO:0042903///tubulin deacetylase activity+++GO:0051787///misfolded protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0051879///Hsp90 protein binding+++GO:0042826///histone deacetylase binding+++GO:0048487///beta-tubulin binding+++GO:0008017///microtubule binding+++GO:0043014///alpha-tubulin binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)","GO:0006886///intracellular protein transport+++GO:0031647///regulation of protein stability+++GO:0060997///dendritic spine morphogenesis+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0048668///collateral sprouting+++GO:0051788///response to misfolded protein+++GO:0070848///response to growth factor+++GO:0032984///protein-containing complex disassembly+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0009967///positive regulation of signal transduction+++GO:0000209///protein polyubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0035967///cellular response to topologically incorrect protein+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0051646///mitochondrion localization+++GO:0060271///cilium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0032461///positive regulation of protein oligomerization+++GO:0045861///negative regulation of proteolysis+++GO:0045598///regulation of fat cell differentiation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0070846///Hsp90 deacetylation+++GO:0009636///response to toxic substance+++GO:0006325///chromatin organization+++GO:0032418///lysosome localization+++GO:0010033///response to organic substance+++GO:0010727///negative regulation of hydrogen peroxide metabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016241///regulation of macroautophagy+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006914///autophagy+++GO:0043242///negative regulation of protein complex disassembly+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:0090042///tubulin deacetylation+++GO:0010506///regulation of autophagy+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0060632///regulation of microtubule-based movement+++GO:0006476///protein deacetylation+++GO:0070201///regulation of establishment of protein localization+++GO:0070842///aggresome assembly+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070845///polyubiquitinated misfolded protein transport+++GO:0010469///regulation of signaling receptor activity+++GO:0070932///histone H3 deacetylation+++GO:0016575///histone deacetylation+++GO:0010634///positive regulation of epithelial cell migration+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0060765///regulation of androgen receptor signaling pathway","histone deacetylase 6","[HDAC6_HUMAN|Reviewed]RecName: Full=Histone deacetylase 6; Short=HD6; EC=3.5.1.98;+++[A0A024QZ26_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8Y4G2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494007}; Flags: Fragment;+++[A0A2R8Y559_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494293}; Flags: Fragment;+++[A0A2R8Y5Z4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495151};+++[A0A2R8Y6Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495932}; Flags: Fragment;+++[A0A2R8Y758_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000496032}; Flags: Fragment;+++[A0A2R8YCS4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000493921}; Flags: Fragment;+++[A0A2R8YD35_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494230}; Flags: Fragment;+++[A0A2R8YDE6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8YGC5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495872}; Flags: Fragment;+++[A6NDI8_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000365831}; Flags: Fragment;+++[B4DZH6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[C9J172_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000392815}; Flags: Fragment;+++[C9JEF4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000403370}; Flags: Fragment;+++[E7EP63_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402751}; Flags: Fragment;+++[E7EPS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402189}; Flags: Fragment;+++[E7ER52_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000394377}; Flags: Fragment;+++[H7C0Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000397697}; Flags: Fragment;+++[Q9BRX7_HUMAN|Unreviewed]SubName: Full=HDAC6 protein {ECO:0000313|EMBL:AAH05872.1}; SubName: Full=Histone deacetylase 6 {ECO:0000313|EMBL:AAP35295.1, ECO:0000313|Ensembl:ENSP00000393916};+++[Q9NSW6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};"]
[100130086,"'HSFX2'",9.42,0,0,3.14,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding","GO:0006351///transcription, DNA-templated","heat shock transcription factor family, X-linked 2","[HSFX1_HUMAN|Reviewed]RecName: Full=Heat shock transcription factor, X-linked;+++[A0A140VK21_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 21 {ECO:0000313|EMBL:AEE61158.1};"]
[100130301,"'C8orf89'",2,0,0,0.666666666666667,{"$nulls":7},"chromosome 8 open reading frame 89","[CH089_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C8orf89 {ECO:0000305};+++[A0A087WUN2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C8orf89 {ECO:0000313|Ensembl:ENSP00000478788};+++[A0A096LNS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C8orf89 {ECO:0000313|Ensembl:ENSP00000485199};"]
[100130311,"'C17orf107'",167,203,141,170.333333333333,"04080///Neuroactive ligand-receptor interaction","H00770///Congenital myasthenic syndrome",{"$nulls":5},"chromosome 17 open reading frame 107","[CQ107_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf107;+++[E5RJ01_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf107 {ECO:0000313|Ensembl:ENSP00000429241};"]
[100130357,"'LOC100130357'",0,4,3,2.33333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","uncharacterized LOC100130357","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RABX5_HUMAN|diamond]RecName: Full=Rab5 GDP/GTP exchange factor; AltName: Full=RAP1; AltName: Full=Rabaptin-5-associated exchange factor for Rab5; AltName: Full=Rabex-5;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[100130361,"'CXorf49'",1,0.5,0.5,0.666666666666667,{"$nulls":7},"chromosome X open reading frame 49","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100130370,"'LOC100130370'",103,172,161,145.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100130370","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100130449,"'LOC100130449'",0,0,2,0.666666666666667,"05418///Fluid shear stress and atherosclerosis+++05205///Proteoglycans in cancer",{"$nulls":3},"GO:0045121///membrane raft+++GO:0046658///anchored component of plasma membrane+++GO:0043025///neuronal cell body+++GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0005768///endosome","GO:0005507///copper ion binding+++GO:0017134///fibroblast growth factor binding+++GO:0070052///collagen V binding+++GO:0043236///laminin binding","GO:0032288///myelin assembly+++GO:2001016///positive regulation of skeletal muscle cell differentiation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0014037///Schwann cell differentiation+++GO:0030200///heparan sulfate proteoglycan catabolic process","uncharacterized LOC100130449","[GPC1_BOVIN|diamond]RecName: Full=Glypican-1; Contains: RecName: Full=Secreted glypican-1; Flags: Precursor;+++[GPC1_HUMAN|diamond]RecName: Full=Glypican-1; Contains: RecName: Full=Secreted glypican-1; Flags: Precursor;+++[GPC1_MOUSE|diamond]RecName: Full=Glypican-1; Contains: RecName: Full=Secreted glypican-1; Flags: Precursor;+++[GPC1_RAT|diamond]RecName: Full=Glypican-1; AltName: Full=HSPG M12; Contains: RecName: Full=Secreted glypican-1; Flags: Precursor;+++[GPC1_XENTR|diamond]RecName: Full=Glypican-1; Contains: RecName: Full=Secreted glypican-1; Flags: Precursor;"]
[100130451,"'LOC100130451'",3,3,2,2.66666666666667,{"$nulls":7},"uncharacterized LOC100130451","[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[100130519,"'TMEM221'",10,19,3,10.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 221","[TM221_HUMAN|Reviewed]RecName: Full=Transmembrane protein 221;"]
[100130705,"'ATP6V1FNB'",21,35,35,30.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"ATP6V1F neighbor","[VAFNB_HUMAN|Reviewed]RecName: Full=Protein ATP6V1FNB {ECO:0000305}; AltName: Full=ATP6V1F neighbor gene protein {ECO:0000305};"]
[100130733,"'LRRC70'",2,2,1,1.66666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005149///interleukin-1 receptor binding","GO:0002237///response to molecule of bacterial origin+++GO:0007409///axonogenesis+++GO:0002224///toll-like receptor signaling pathway","leucine rich repeat containing 70","[LRR70_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 70; AltName: Full=Synleurin; Flags: Precursor;+++[D6RD14_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 70 {ECO:0000313|Ensembl:ENSP00000427117};"]
[100130771,"'EFCAB10'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0010494///cytoplasmic stress granule+++GO:0005576///extracellular region+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0070939///Dsl1/NZR complex+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0005509///calcium ion binding","GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0006397///mRNA processing+++GO:0015031///protein transport+++GO:0006351///transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0051781///positive regulation of cell division+++GO:1902504///regulation of signal transduction involved in mitotic G2 DNA damage checkpoint+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007049///cell cycle+++GO:0006355///regulation of transcription, DNA-templated","EF-hand calcium binding domain 10","[EFC10_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 10;+++[A0A2R8Y6P2_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000495682};+++[A0A2R8YDC4_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000494437};+++[C9J654_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000418425};+++[J3KR48_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417484}; SubName: Full=HCG1779729, isoform CRA_a {ECO:0000313|EMBL:EAW83368.1};+++[J3KR52_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417841};"]
[100130827,"'SBK3'",1,0,0,0.333333333333333,{"$nulls":5},"GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","SH3 domain binding kinase family member 3","[SBK3_HUMAN|Reviewed]RecName: Full=Uncharacterized serine/threonine-protein kinase SBK3; EC=2.7.11.1; AltName: Full=SH3-binding domain kinase family member 3; AltName: Full=Sugen kinase 110;+++[K7EP79_HUMAN|Unreviewed]SubName: Full=Uncharacterized serine/threonine-protein kinase SBK3 {ECO:0000313|Ensembl:ENSP00000467263}; Flags: Fragment;"]
[100130890,"'TSTD3'",95.38,106.03,91.17,97.5266666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016592///mediator complex+++GO:0005829///cytosol+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0070911///global genome nucleotide-excision repair+++GO:0016579///protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1901409///positive regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:0006281///DNA repair+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II","thiosulfate sulfurtransferase like domain containing 3","[TSTD3_HUMAN|Reviewed]RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3; AltName: Full=Rhodanese domain-containing protein 3;+++[A0A1B0GUB9_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000490043};"]
[100130933,"'SMIM6'",4,4,2,3.33333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0016020///membrane+++GO:0071953///elastic fiber+++GO:0062023///collagen-containing extracellular matrix+++GO:0016021///integral component of membrane","GO:0050840///extracellular matrix binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0005515///protein binding+++GO:0005201///extracellular matrix structural constituent","GO:0007519///skeletal muscle tissue development+++GO:0043149///stress fiber assembly+++GO:0008283///cell proliferation+++GO:0003180///aortic valve morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0008015///blood circulation+++GO:0009887///animal organ morphogenesis+++GO:0030833///regulation of actin filament polymerization+++GO:0007585///respiratory gaseous exchange+++GO:0030198///extracellular matrix organization","small integral membrane protein 6","[SMIM6_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 6;+++[A7L3I8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:ABS29265.1};+++[D3DXF3_HUMAN|Unreviewed]SubName: Full=Elastin (Supravalvular aortic stenosis, Williams-Beuren syndrome), isoform CRA_b {ECO:0000313|EMBL:EAW69630.1};+++[E7EN51_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000403961}; Flags: Fragment;+++[E7ENW7_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000411092}; Flags: Fragment;+++[E7EP82_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000389206}; Flags: Fragment;+++[E7EQH8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000394549}; Flags: Fragment;+++[E7ETP7_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000406949}; Flags: Fragment;+++[E7EWS8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000399499}; Flags: Fragment;+++[E9PGX4_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000404138};+++[H7C3K0_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000412262}; Flags: Fragment;+++[Q9UME9_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:AAC99789.1}; Flags: Fragment;+++[Q9UMK5_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:AAA52379.1}; Flags: Fragment;"]
[100130958,"'SYCE1L'",28,17,22,22.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04138///Autophagy - yeast",{"$nulls":3},"GO:0000795///synaptonemal complex+++GO:0045111///intermediate filament cytoskeleton",null,"GO:0051321///meiotic cell cycle+++GO:0070193///synaptonemal complex organization+++GO:0007130///synaptonemal complex assembly","synaptonemal complex central element protein 1 like","[SYC1L_HUMAN|Reviewed]RecName: Full=Synaptonemal complex central element protein 1-like; AltName: Full=Meiosis-related protein;+++[H3BME6_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex central element protein 1-like {ECO:0000313|Ensembl:ENSP00000454349}; Flags: Fragment;"]
[100130967,"'C6orf99'",34,21,17,24,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"chromosome 6 open reading frame 99","[CF099_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C6orf99;"]
[100131017,"'ZNF316'",765,814,738,772.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 316","[ZN316_HUMAN|Reviewed]RecName: Full=Zinc finger protein 316;+++[A0A087WZ61_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 316 {ECO:0000313|Ensembl:ENSP00000482395}; Flags: Fragment;"]
[100131187,"'TSTD1'",129,122,115,122,{"$nulls":4},"GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005615///extracellular space+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005739///mitochondrion","GO:0008097///5S rRNA binding+++GO:0004792///thiosulfate sulfurtransferase activity+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0050337///thiosulfate-thiol sulfurtransferase activity","GO:0051029///rRNA transport+++GO:0030855///epithelial cell differentiation+++GO:0070221///sulfide oxidation, using sulfide:quinone oxidoreductase+++GO:0035928///rRNA import into mitochondrion+++GO:0000098///sulfur amino acid catabolic process+++GO:0009440///cyanate catabolic process","thiosulfate sulfurtransferase like domain containing 1","[TSTD1_HUMAN|Reviewed]RecName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000303|PubMed:24981631}; Short=TST {ECO:0000303|PubMed:24981631}; EC=2.8.1.- {ECO:0000269|PubMed:24981631};+++[B1AH48_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase {ECO:0000313|Ensembl:ENSP00000400764}; Flags: Fragment;+++[R4GNF9_HUMAN|Unreviewed]SubName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000313|Ensembl:ENSP00000473633};"]
[100131211,"'NEMP2'",35,24,25,28,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005635///nuclear envelope","GO:0003964///RNA-directed DNA polymerase activity",null,"nuclear envelope integral membrane protein 2","[NEMP2_HUMAN|Reviewed]RecName: Full=Nuclear envelope integral membrane protein 2; Flags: Precursor;+++[C9J4F2_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000410306}; Flags: Fragment;+++[F8VWJ7_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000340087};+++[H7C232_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000403867}; Flags: Fragment;"]
[100131244,"'ANKRD63'",8,5,8,7,{"$nulls":7},"ankyrin repeat domain 63","[ANR63_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 63 {ECO:0000312|HGNC:HGNC:40027};"]
[100131378,"'C11orf91'",0,1,0,0.333333333333333,{"$nulls":7},"chromosome 11 open reading frame 91","[CK091_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf91;+++[H0YDE1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf91 {ECO:0000313|Ensembl:ENSP00000433460}; Flags: Fragment;"]
[100131390,"'SP9'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0030326///embryonic limb morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II","Sp9 transcription factor","[SP9_HUMAN|Reviewed]RecName: Full=Transcription factor Sp9;"]
[100131539,"'ZNF705E'",0,1,1,0.666666666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 705E","[Z705E_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 705E;"]
[100131608,"'PRR23D1'",0.09,0,0,0.03,{"$nulls":7},"proline rich 23 domain containing 1","[P23D1_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D1;+++[P23D2_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D2;"]
[100131755,"'ARMCX4'",84,96,92,90.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0016018///cyclosporin A binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0046790///virion binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0051082///unfolded protein binding","GO:0048469///cell maturation+++GO:0071226///cellular response to molecule of fungal origin+++GO:0035556///intracellular signal transduction+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0019061///uncoating of virus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0098761///cellular response to interleukin-7+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0034389///lipid droplet organization+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0002721///regulation of B cell cytokine production+++GO:0019076///viral release from host cell+++GO:0006351///transcription, DNA-templated+++GO:0045579///positive regulation of B cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0002553///histamine secretion by mast cell+++GO:0097190///apoptotic signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0006310///DNA recombination+++GO:0075713///establishment of integrated proviral latency+++GO:0045087///innate immune response+++GO:0002344///B cell affinity maturation+++GO:0050853///B cell receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0030260///entry into host cell+++GO:0019722///calcium-mediated signaling+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0002250///adaptive immune response+++GO:0034614///cellular response to reactive oxygen species+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0030889///negative regulation of B cell proliferation+++GO:0050900///leukocyte migration+++GO:0019058///viral life cycle+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0007498///mesoderm development+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0019068///virion assembly+++GO:0042113///B cell activation+++GO:0045069///regulation of viral genome replication+++GO:0002902///regulation of B cell apoptotic process+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0001818///negative regulation of cytokine production+++GO:0006468///protein phosphorylation+++GO:0032197///transposition, RNA-mediated","armadillo repeat containing X-linked 4","[ARMX4_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 4;+++[A0A024RCH4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 4, isoform CRA_b {ECO:0000313|EMBL:EAX02871.1};+++[D6RBS8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000422573};+++[F8W8Y7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000404304};+++[L8EAW9_HUMAN|Unreviewed]SubName: Full=Alternative protein ARMCX4 {ECO:0000313|EMBL:CCQ43981.1};"]
[100131801,"'PET100'",248,203,222,224.333333333333,"03040///Spliceosome","H01368///Cytochrome c oxidase (COX) deficiency","M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0051082///unfolded protein binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","PET100 homolog","[PT100_HUMAN|Reviewed]RecName: Full=Protein PET100 homolog, mitochondrial; Flags: Precursor;+++[A0A0A0MSK2_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000392303};+++[M0QZ55_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470314}; Flags: Fragment;+++[M0R022_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470935};"]
[100131827,"'ZNF717'",54,54,46,51.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 717","[ZN717_HUMAN|Reviewed]RecName: Full=Zinc finger protein 717; AltName: Full=Krueppel-like factor X17;+++[C9J5W8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000417902};+++[C9J8I7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000418187}; Flags: Fragment;+++[C9JVC3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000419377};+++[E5RKB3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000420241}; Flags: Fragment;"]
[100131897,"'INSYN2B'",30,37,40,35.6666666666667,"04062///Chemokine signaling pathway+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0035580///specific granule lumen+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0042608///T cell receptor binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0050766///positive regulation of phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0001766///membrane raft polarization+++GO:0045059///positive thymic T cell selection+++GO:0044351///macropinocytosis+++GO:0045060///negative thymic T cell selection+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0006935///chemotaxis+++GO:0050690///regulation of defense response to virus by virus+++GO:0001771///immunological synapse formation+++GO:0007264///small GTPase mediated signal transduction+++GO:0001768///establishment of T cell polarity+++GO:0046633///alpha-beta T cell proliferation","inhibitory synaptic factor family member 2B","[INY2B_HUMAN|Reviewed]RecName: Full=Protein INSYN2B {ECO:0000305}; AltName: Full=Inhibitory synaptic factor family member 2B {ECO:0000312|HGNC:HGNC:37271};"]
[100132074,"'FOXO6'",603,514,467,528,"04068///FoxO signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0042593///glucose homeostasis+++GO:0008286///insulin receptor signaling pathway+++GO:0007613///memory+++GO:0060999///positive regulation of dendritic spine development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","forkhead box O6","[FOXO6_HUMAN|Reviewed]RecName: Full=Forkhead box protein O6;+++[A0A1X9RU27_HUMAN|Unreviewed]SubName: Full=Forkhead box protein O6 {ECO:0000313|EMBL:ARQ84049.1};"]
[100132146,"'FAM240A'",1,0,0,0.333333333333333,{"$nulls":7},"family with sequence similarity 240 member A","[F240A_HUMAN|Reviewed]RecName: Full=Protein FAM240A {ECO:0000305};+++[A0A286YEV0_HUMAN|Unreviewed]SubName: Full=Protein FAM240A {ECO:0000313|Ensembl:ENSP00000490556};"]
[100132247,"'NPIPB5'",3196.98,6198.1,4261.98,4552.35333333333,"00650///Butanoate metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++01100///Metabolic pathways",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane",null,null,"nuclear pore complex interacting protein family member B5","[NPIB5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B5;+++[B4E0Y1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61599 {ECO:0000313|EMBL:BAG64593.1};+++[E5RHP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000456511}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000429523}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000428548}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449726};+++[E7EUG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000392155};+++[E9PKP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000431553}; Flags: Fragment;+++[F5GWQ4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000457242}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000442776}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441759}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449771};+++[F5GXZ6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000440137}; Flags: Fragment;+++[F5GYP3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441303}; Flags: Fragment;+++[F5GZP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000444299}; Flags: Fragment;+++[F5H6Y6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442935}; Flags: Fragment;+++[F6SDX0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000445388}; Flags: Fragment;+++[H0YIL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000449628}; Flags: Fragment;+++[U3KRG3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442912}; Flags: Fragment;"]
[100132406,"'NBPF10'",658.1,1074.46,778.97,837.176666666667,"01522///Endocrine resistance+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++04140///Autophagy - animal+++05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation+++04137///Mitophagy - animal+++05224///Breast cancer","H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0003723///RNA binding","GO:0007275///multicellular organism development+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway","NBPF member 10","[NBPFA_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 10;+++[A0A075B762_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000463957};+++[A0A087WVC7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000479344};+++[A0A087WVG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000479415};+++[A0A087WYQ9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482016};+++[A0A087WZE1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482587};+++[A0A087X0Y3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000483736};+++[A2BH96_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 10 {ECO:0000313|EMBL:CAM23768.1};+++[I0CMK7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFH78588.1}; Flags: Fragment;+++[I1VE12_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41822.1}; Flags: Fragment;+++[I1VE13_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41823.1}; Flags: Fragment;+++[I1VE14_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41824.1}; Flags: Fragment;+++[L8E7E2_HUMAN|Unreviewed]SubName: Full=Alternative protein NBPF9 {ECO:0000313|EMBL:CCQ43049.1};+++[Q5TB04_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 9 {ECO:0000313|EMBL:CAI22821.1}; Flags: Fragment;"]
[100132813,"'LOC100132813'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC100132813","[A0A0D9RFT1_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000007470};+++[A0A2K5ELV0_AOTNA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSANAP00000034188};+++[A0A2K5HE23_COLAP|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCANP00000002593};+++[A0A2K6TW16_SAIBB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSBOP00000023852};+++[I7GCC4_MACFA|diamond]SubName: Full=Macaca fascicularis brain cDNA, clone: QflA-18945 {ECO:0000313|EMBL:BAE89674.1};"]
[100132874,"'LOC100132874'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC100132874","[RRBP1_MOUSE|diamond]RecName: Full=Ribosome-binding protein 1; AltName: Full=Ribosome receptor protein; Short=RRp; Short=mRRp;+++[SRFB1_XENTR|diamond]RecName: Full=Serum response factor-binding protein 1; AltName: Full=SRF-dependent transcription regulation-associated protein;"]
[100132911,"'DPH3P1'",5,0,0,1.66666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046872///metal ion binding","GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0002098///tRNA wobble uridine modification","diphthamide biosynthesis 3 pseudogene 1","[DPH3B_HUMAN|Reviewed]RecName: Full=Putative DPH3 homolog B; AltName: Full=CSL-type zinc finger-containing protein 1;"]
[100132994,"'CXorf49B'",1,0.5,0.5,0.666666666666667,{"$nulls":7},"chromosome X open reading frame 49B","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100133093,"'FAM25G'",3,1,0,1.33333333333333,{"$nulls":7},"family with sequence similarity 25 member G","[FM25A_HUMAN|Reviewed]RecName: Full=Protein FAM25A {ECO:0000305};+++[FM25C_HUMAN|Reviewed]RecName: Full=Protein FAM25C {ECO:0000305};+++[FM25G_HUMAN|Reviewed]RecName: Full=Protein FAM25G {ECO:0000305};+++[B7ZW47_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 25, member C {ECO:0000313|EMBL:AAI71871.1};"]
[100133204,"'C9orf147'",2,7,10,6.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0016020///membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0051213///dioxygenase activity","GO:0010468///regulation of gene expression","chromosome 9 open reading frame 147","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[HSDL2_BOVIN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_HUMAN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-; AltName: Full=Short chain dehydrogenase/reductase family 13C member 1;+++[HSDL2_PONAB|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENLA|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENTR|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100133220,"'GOLGA6L3'",0,2.69,0.62,1.10333333333333,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"golgin A6 family-like 3","[GG6L3_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 3;"]
[100133251,"'PRR23D2'",2.91,1,0,1.30333333333333,{"$nulls":7},"proline rich 23 domain containing 2","[P23D1_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D1;+++[P23D2_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D2;"]
[100133301,"'100133301'",2,6,2,3.33333333333333,{"$nulls":8},"[F231A_HUMAN|diamond]RecName: Full=Putative protein FAM231AP {ECO:0000305};+++[F231B_HUMAN|diamond]RecName: Full=Putative protein FAM231BP;+++[F231C_HUMAN|diamond]RecName: Full=Protein FAM231C;+++[F231D_HUMAN|diamond]RecName: Full=Protein FAM231D;+++[F231L_HUMAN|diamond]RecName: Full=FAM231A/C-like protein LOC102723383;"]
[100133941,"'CD24'",1777,1259,1421,1485.66666666667,"04640///Hematopoietic cell lineage",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0045121///membrane raft+++GO:0009986///cell surface+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030296///protein tyrosine kinase activator activity","GO:0032597///B cell receptor transport into membrane raft+++GO:0032913///negative regulation of transforming growth factor beta3 production+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0030856///regulation of epithelial cell differentiation+++GO:0045730///respiratory burst+++GO:0043406///positive regulation of MAP kinase activity+++GO:0016055///Wnt signaling pathway+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:2000768///positive regulation of nephron tubule epithelial cell differentiation+++GO:0001775///cell activation+++GO:0042632///cholesterol homeostasis+++GO:0002237///response to molecule of bacterial origin+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072139///glomerular parietal epithelial cell differentiation+++GO:0001666///response to hypoxia+++GO:0042325///regulation of phosphorylation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0032600///chemokine receptor transport out of membrane raft+++GO:0043408///regulation of MAPK cascade+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0031295///T cell costimulation+++GO:0043627///response to estrogen+++GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0098609///cell-cell adhesion","CD24 molecule","[CD24_HUMAN|Reviewed]RecName: Full=Signal transducer CD24; AltName: Full=Small cell lung carcinoma cluster 4 antigen; AltName: CD_antigen=CD24; Flags: Precursor;+++[A0A087WU21_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478302};+++[A0A087WU87_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478460}; Flags: Fragment;+++[A0A087WW33_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000479895}; Flags: Fragment;"]
[100134934,"'TEN1'",141,154,184,159.666666666667,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0005634///nucleus+++GO:0000781///chromosome, telomeric region+++GO:1990879///CST complex+++GO:0005694///chromosome","GO:0042162///telomeric DNA binding+++GO:0005515///protein binding+++GO:0010521///telomerase inhibitor activity+++GO:0003697///single-stranded DNA binding+++GO:0003677///DNA binding","GO:0016233///telomere capping+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0051974///negative regulation of telomerase activity","TEN1, CST complex subunit","[TEN1L_HUMAN|Reviewed]RecName: Full=CST complex subunit TEN1; AltName: Full=Protein telomeric pathways with STN1 homolog; AltName: Full=Telomere length regulation protein TEN1 homolog;+++[D3U720_HUMAN|Unreviewed]SubName: Full=Telomeric pathways in association with Stn1 number 1 {ECO:0000313|EMBL:ACY71128.1};+++[K7EIL0_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000464792}; Flags: Fragment;+++[K7EJS2_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465299}; Flags: Fragment;+++[K7EL09_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465866};"]
[100134938,"'UPK3BL1'",288.18,362.6,290.23,313.67,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"uroplakin 3B like 1","[UPK3L_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 1 {ECO:0000312|HGNC:HGNC:37278}; Flags: Precursor;+++[UPKL2_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 2 {ECO:0000305}; Flags: Precursor;"]
[100137047,"'JMJD7'",117.76,98.46,112.49,109.57,{"$nulls":5},"GO:0005515///protein binding",null,"jumonji domain containing 7","[JMJD7_HUMAN|Reviewed]RecName: Full=JmjC domain-containing protein 7; AltName: Full=Jumonji domain-containing protein 7;+++[B5MC20_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000384174};+++[C9K0I3_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000399600}; Flags: Fragment;"]
[10014,"'HDAC5'",1754,1962,1546,1754,"04371///Apelin signaling pathway+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05034///Alcoholism+++05203///Viral carcinogenesis","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0005829///cytosol+++GO:0000118///histone deacetylase complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0008134///transcription factor binding+++GO:0003682///chromatin binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0070491///repressing transcription factor binding+++GO:0005515///protein binding+++GO:0005080///protein kinase C binding+++GO:0033558///protein deacetylase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0030183///B cell differentiation+++GO:0010830///regulation of myotube differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006954///inflammatory response+++GO:0042113///B cell activation+++GO:0014823///response to activity+++GO:0010832///negative regulation of myotube differentiation+++GO:0042493///response to drug+++GO:0043393///regulation of protein binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042220///response to cocaine+++GO:0040029///regulation of gene expression, epigenetic+++GO:0030182///neuron differentiation+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0006338///chromatin remodeling+++GO:0070932///histone H3 deacetylation+++GO:0006476///protein deacetylation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006325///chromatin organization+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0006342///chromatin silencing+++GO:0016575///histone deacetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032869///cellular response to insulin stimulus","histone deacetylase 5","[HDAC5_HUMAN|Reviewed]RecName: Full=Histone deacetylase 5; Short=HD5; EC=3.5.1.98; AltName: Full=Antigen NY-CO-9;+++[K7EJL4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465227}; Flags: Fragment;+++[K7EJL6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465229}; Flags: Fragment;+++[K7EJZ7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465393}; Flags: Fragment;+++[K7ES01_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000468485}; Flags: Fragment;"]
[100142659,"'CTAGE8'",24.85,30.96,20.95,25.5866666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0042954///lipoprotein transporter activity","GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0042953///lipoprotein transport","CTAGE family member 8","[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[CTGE8_HUMAN|Reviewed]RecName: Full=cTAGE family member 8; Short=Protein cTAGE-8;"]
[100144595,"'LOC100144595'",1,0,1,0.666666666666667,{"$nulls":7},"uncharacterized LOC100144595","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100144748,"'KLLN'",30,41,26,32.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003677///DNA binding","GO:0006915///apoptotic process+++GO:0007050///cell cycle arrest+++GO:0007049///cell cycle","killin, p53 regulated DNA replication inhibitor","[KILIN_HUMAN|Reviewed]RecName: Full=Killin;"]
[10015,"'PDCD6IP'",2249,2271,2155,2225,"04144///Endocytosis",{"$nulls":3},"GO:0001772///immunological synapse+++GO:0005923///bicellular tight junction+++GO:0042470///melanosome+++GO:0070971///endoplasmic reticulum exit site+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:1903561///extracellular vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0042641///actomyosin+++GO:0005815///microtubule organizing center+++GO:0005925///focal adhesion+++GO:0090543///Flemming body","GO:0048306///calcium-dependent protein binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0031871///proteinase activated receptor binding","GO:1903543///positive regulation of exosomal secretion+++GO:0070830///bicellular tight junction assembly+++GO:0007080///mitotic metaphase plate congression+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:0019058///viral life cycle+++GO:0016032///viral process+++GO:0046755///viral budding+++GO:1903551///regulation of extracellular exosome assembly+++GO:0015031///protein transport+++GO:0006997///nucleus organization+++GO:0000281///mitotic cytokinesis+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0007049///cell cycle+++GO:1901673///regulation of mitotic spindle assembly+++GO:0000915///actomyosin contractile ring assembly+++GO:0039702///viral budding via host ESCRT complex+++GO:0051260///protein homooligomerization+++GO:0010824///regulation of centrosome duplication+++GO:0036258///multivesicular body assembly+++GO:1903553///positive regulation of extracellular exosome assembly+++GO:0006915///apoptotic process+++GO:0090559///regulation of membrane permeability+++GO:0061952///midbody abscission+++GO:0051301///cell division","programmed cell death 6 interacting protein","[PDC6I_HUMAN|Reviewed]RecName: Full=Programmed cell death 6-interacting protein; Short=PDCD6-interacting protein; AltName: Full=ALG-2-interacting protein 1; AltName: Full=ALG-2-interacting protein X; AltName: Full=Hp95;+++[C9IZF9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000406693}; Flags: Fragment;+++[F8WBR8_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000398895};+++[F8WDK9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000415150};+++[F8WEQ7_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000393777};+++[Q4W4Y1_HUMAN|Unreviewed]SubName: Full=Dopamine receptor interacting protein 4 {ECO:0000313|EMBL:AAQ14260.1};"]
[10016,"'PDCD6'",443,424,414,427,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030127///COPII vesicle coat+++GO:0070062///extracellular exosome+++GO:0005768///endosome+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0015629///actin cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0060090///molecular adaptor activity+++GO:0005509///calcium ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0000287///magnesium ion binding+++GO:0004378///GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0102704///GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity","GO:1902527///positive regulation of protein monoubiquitination+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0014029///neural crest formation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097502///mannosylation+++GO:0006486///protein glycosylation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0001525///angiogenesis+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0034605///cellular response to heat+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006886///intracellular protein transport+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006915///apoptotic process+++GO:0051592///response to calcium ion+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0014032///neural crest cell development+++GO:0045766///positive regulation of angiogenesis+++GO:0010595///positive regulation of endothelial cell migration","programmed cell death 6","[PDCD6_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 6; AltName: Full=Apoptosis-linked gene 2 protein homolog {ECO:0000250|UniProtKB:P12815}; Short=ALG-2 {ECO:0000250|UniProtKB:P12815};+++[A0A024QZ42_HUMAN|Unreviewed]SubName: Full=HCG1985580, isoform CRA_c {ECO:0000313|EMBL:EAW50990.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000485024};+++[A0A087WZ38_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000482332};+++[D6RA21_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000424201};+++[E7EPW6_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000426003};+++[H0Y9X3_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000425370}; Flags: Fragment;+++[Q53FC3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6 variant {ECO:0000313|EMBL:BAD97086.1}; Flags: Fragment;+++[Q86W51_HUMAN|Unreviewed]SubName: Full=PDCD6 protein {ECO:0000313|EMBL:AAH50597.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000422691};"]
[10017,"'BCL2L10'",13,9,13,11.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0089720///caspase binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0007283///spermatogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007292///female gamete generation","BCL2 like 10","[B2L10_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 10; Short=Bcl2-L-10; AltName: Full=Anti-apoptotic protein NrH; AltName: Full=Apoptosis regulator Bcl-B;+++[H0YMD5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 10 {ECO:0000313|Ensembl:ENSP00000453562};"]
[100170229,"'SRRM5'",4,3,3,3.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","serine/arginine repetitive matrix 5","[SRRM5_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 5;+++[Q4G0Z0_HUMAN|Unreviewed]SubName: Full=LOC100170229 protein {ECO:0000313|EMBL:AAH34980.1}; Flags: Fragment;"]
[100170841,"'EPOP'",69,54,45,56,{"$nulls":4},"GO:0070449///elongin complex+++GO:0035098///ESC/E(Z) complex+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0003682///chromatin binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0048863///stem cell differentiation+++GO:0048663///neuron fate commitment","elongin BC and polycomb repressive complex 2 associated protein","[EPOP_HUMAN|Reviewed]RecName: Full=Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8}; AltName: Full=Proline-rich protein 28 {ECO:0000312|HGNC:HGNC:34493};"]
[10018,"'BCL2L11'",194,172,160,175.333333333333,"04210///Apoptosis+++05206///MicroRNAs in cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++04215///Apoptosis - multiple species+++01521///EGFR tyrosine kinase inhibitor resistance+++05210///Colorectal cancer+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0005829///cytosol+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex+++GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097140///BIM-BCL-xl complex+++GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0097141///BIM-BCL-2 complex","GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0019901///protein kinase binding","GO:0008584///male gonad development+++GO:0048536///spleen development+++GO:0035148///tube formation+++GO:0001822///kidney development+++GO:0048538///thymus development+++GO:0009791///post-embryonic development+++GO:0001783///B cell apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0007420///brain development+++GO:0045787///positive regulation of cell cycle+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0048066///developmental pigmentation+++GO:0002262///myeloid cell homeostasis+++GO:0001701///in utero embryonic development+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0032464///positive regulation of protein homooligomerization+++GO:0010942///positive regulation of cell death+++GO:0070242///thymocyte apoptotic process+++GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0007160///cell-matrix adhesion+++GO:0002260///lymphocyte homeostasis+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0001782///B cell homeostasis+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:0046620///regulation of organ growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0030879///mammary gland development+++GO:0043583///ear development+++GO:0006915///apoptotic process+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0043029///T cell homeostasis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0001776///leukocyte homeostasis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043065///positive regulation of apoptotic process+++GO:0034263///positive regulation of autophagy in response to ER overload+++GO:0048070///regulation of developmental pigmentation+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0007283///spermatogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0060154///cellular process regulating host cell cycle in response to virus+++GO:0060139///positive regulation of apoptotic process by virus","BCL2 like 11","[B2L11_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 11; Short=Bcl2-L-11; AltName: Full=Bcl2-interacting mediator of cell death;+++[A0A0A0MRE7_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000350398};+++[A0A0C4DH20_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000354879};+++[C9J417_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000411870}; Flags: Fragment;+++[E9PAM9_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000376941}; Flags: Fragment;+++[H7BZE5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000389225}; Flags: Fragment;"]
[100188893,"'TOMM6'",668,649,624,647,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005742///mitochondrial outer membrane translocase complex",null,"GO:0015031///protein transport","translocase of outer mitochondrial membrane 6","[TOM6_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM6 homolog; AltName: Full=Overexpressed breast tumor protein; AltName: Full=Translocase of outer membrane 6 kDa subunit homolog;"]
[10019,"'SH2B3'",238,185,192,205,"04722///Neurotrophin signaling pathway","H00408///Type I diabetes mellitus",null,null,"GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0035591///signaling adaptor activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding","GO:0007596///blood coagulation+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0009967///positive regulation of signal transduction+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0035162///embryonic hemopoiesis","SH2B adaptor protein 3","[SH2B3_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 3; AltName: Full=Lymphocyte adapter protein; AltName: Full=Lymphocyte-specific adapter protein Lnk; AltName: Full=Signal transduction protein Lnk;+++[B7Z7K6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54917, highly similar to Lymphocyte-specific adapter protein Lnk {ECO:0000313|EMBL:BAH13642.1};+++[F5GYM4_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000440597};+++[Q59H48_HUMAN|Unreviewed]SubName: Full=Lymphocyte adaptor protein variant {ECO:0000313|EMBL:BAD92148.1}; Flags: Fragment;+++[Q96BA5_HUMAN|Unreviewed]SubName: Full=SH2B3 protein {ECO:0000313|EMBL:AAH15786.1};+++[R4GN84_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000473529}; Flags: Fragment;"]
[100191040,"'C2CD4D'",18,18,20,18.6666666666667,{"$nulls":4},"GO:0098793///presynapse+++GO:0005886///plasma membrane","GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding",null,"C2 calcium dependent domain containing 4D","[C2D4D_HUMAN|Reviewed]RecName: Full=C2 calcium-dependent domain-containing protein 4D;"]
[1002,"'CDH4'",69,61,57,62.3333333333333,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0016342///catenin complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007411///axon guidance+++GO:0045773///positive regulation of axon extension+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization","cadherin 4","[CADH4_HUMAN|Reviewed]RecName: Full=Cadherin-4; AltName: Full=Retinal cadherin; Short=R-CAD; Short=R-cadherin; Flags: Precursor;+++[A0A087WX99_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000480844};+++[A0A0G2JRA4_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000486568}; Flags: Fragment;"]
[10020,"'GNE'",278.56,293.65,280.97,284.393333333333,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H00596///Nonaka distal myopathy (NM)+++H00594///Distal myopathy+++H00147///Sialuria",null,"R02705///ATP:N-acyl-D-mannosamine 6-phosphotransferase   ATP + N-Acetyl-D-mannosamine <=> ADP + N-Acetyl-D-mannosamine 6-phosphate+++R00414///UDP-N-acetyl-D-glucosamine 2-epimerase   UDP-N-acetyl-alpha-D-glucosamine + H2O <=> N-Acetyl-D-mannosamine + UDP","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008761///UDP-N-acetylglucosamine 2-epimerase activity+++GO:0009384///N-acylmannosamine kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity+++GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0008152///metabolic process+++GO:0006054///N-acetylneuraminate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006045///N-acetylglucosamine biosynthetic process+++GO:0007155///cell adhesion+++GO:0016310///phosphorylation","glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase","[GLCNE_HUMAN|Reviewed]RecName: Full=Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; AltName: Full=UDP-GlcNAc-2-epimerase/ManAc kinase; Includes: RecName: Full=UDP-N-acetylglucosamine 2-epimerase (hydrolyzing); EC=3.2.1.183; AltName: Full=UDP-GlcNAc-2-epimerase; AltName: Full=Uridine diphosphate-N-acetylglucosamine-2-epimerase; Includes: RecName: Full=N-acetylmannosamine kinase; EC=2.7.1.60; AltName: Full=ManAc kinase;+++[Q6QNY5_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59259.1};+++[Q6QNY6_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59258.1};+++[Q6QNY7_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59257.1};"]
[10021,"'HCN4'",6,6,4,5.33333333333333,"04024///cAMP signaling pathway+++04742///Taste transduction","H00729///Sick sinus syndrome (SSS)+++H00728///Brugada syndrome (BRS)",null,null,"GO:0098855///HCN channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0005267///potassium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0042802///identical protein binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0030552///cAMP binding+++GO:0005249///voltage-gated potassium channel activity+++GO:0086041///voltage-gated potassium channel activity involved in SA node cell action potential depolarization+++GO:0000166///nucleotide binding+++GO:0005272///sodium channel activity","GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0071321///cellular response to cGMP+++GO:0006813///potassium ion transport+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0008015///blood circulation+++GO:0071805///potassium ion transmembrane transport+++GO:0086015///SA node cell action potential+++GO:0098719///sodium ion import across plasma membrane+++GO:0003254///regulation of membrane depolarization+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0006936///muscle contraction+++GO:0034765///regulation of ion transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0002027///regulation of heart rate+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential","hyperpolarization activated cyclic nucleotide gated potassium channel 4","[HCN4_HUMAN|Reviewed]RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4;"]
[10023,"'FRAT1'",16,21,15,17.3333333333333,"05200///Pathways in cancer+++05225///Hepatocellular carcinoma+++04310///Wnt signaling pathway+++05224///Breast cancer+++05226///Gastric cancer",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding","GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0060070///canonical Wnt signaling pathway+++GO:1904886///beta-catenin destruction complex disassembly","FRAT1, WNT signaling pathway regulator","[FRAT1_HUMAN|Reviewed]RecName: Full=Proto-oncogene FRAT1; AltName: Full=Frequently rearranged in advanced T-cell lymphomas 1; Short=FRAT-1;+++[D3DR49_HUMAN|Unreviewed]SubName: Full=Frequently rearranged in advanced T-cell lymphomas, isoform CRA_a {ECO:0000313|EMBL:EAW49951.1};"]
[10024,"'TROAP'",1,13,4,6,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0007155///cell adhesion","trophinin associated protein","[TROAP_HUMAN|Reviewed]RecName: Full=Tastin; AltName: Full=Trophinin-assisting protein; AltName: Full=Trophinin-associated protein;+++[B7Z5Q9_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000450306}; SubName: Full=cDNA FLJ50628, highly similar to Trophinin-associated protein {ECO:0000313|EMBL:BAH12995.1};+++[F8VR46_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446564};+++[F8VVS4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449588}; Flags: Fragment;+++[F8VVT5_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449245};+++[F8VVX4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449866};+++[F8VXF3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449984};+++[F8VXV6_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449032};+++[F8W052_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447244}; Flags: Fragment;+++[F8W130_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447509};+++[F8W1E3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446646}; Flags: Fragment;+++[F8W1U0_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447421};"]
[10025,"'MED16'",1427,1544,1506,1492.33333333333,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005634///nucleus","GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0003824///catalytic activity+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042809///vitamin D receptor binding","GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030518///intracellular steroid hormone receptor signaling pathway","mediator complex subunit 16","[MED16_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16; AltName: Full=Mediator complex subunit 16; AltName: Full=Thyroid hormone receptor-associated protein 5; AltName: Full=Thyroid hormone receptor-associated protein complex 95 kDa component; Short=Trap95; AltName: Full=Vitamin D3 receptor-interacting protein complex 92 kDa component; Short=DRIP92;+++[A0A087WU12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YW49_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXA0_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000488370}; Flags: Fragment;+++[A0A0J9YXK9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXL6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YY02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YYC6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ7_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i4 {ECO:0000313|EMBL:ACB88883.1}; Flags: Fragment;+++[B9TWZ8_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX00_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX01_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX03_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i10 {ECO:0000313|EMBL:ACB88889.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000480766}; Flags: Fragment;+++[B9TX04_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX05_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX06_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX07_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i14 {ECO:0000313|EMBL:ACB88893.1}; Flags: Fragment;+++[B9TX08_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i15 {ECO:0000313|EMBL:ACB88894.1}; Flags: Fragment;+++[B9TX09_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX10_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i17 {ECO:0000313|EMBL:ACB88896.1}; Flags: Fragment;+++[B9TX11_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX13_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i20 {ECO:0000313|EMBL:ACB88899.1}; Flags: Fragment;+++[B9TX14_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i21 {ECO:0000313|EMBL:ACB88900.1};+++[B9TX15_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i22 {ECO:0000313|EMBL:ACB88901.1}; Flags: Fragment;+++[B9TX16_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i23 {ECO:0000313|EMBL:ACB88902.1};+++[B9TX17_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i24 {ECO:0000313|EMBL:ACB88903.1};+++[B9TX18_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i25 {ECO:0000313|EMBL:ACB88904.1};+++[B9TX19_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i26 {ECO:0000313|EMBL:ACB88905.1};+++[B9TX20_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i27 {ECO:0000313|EMBL:ACB88906.1};+++[B9TX21_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i28 {ECO:0000313|EMBL:ACB88907.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000483533};+++[B9TX22_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i29 {ECO:0000313|EMBL:ACB88908.1};+++[B9TX23_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i30 {ECO:0000313|EMBL:ACB88909.1};+++[B9TX24_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i31 {ECO:0000313|EMBL:ACB88910.1};+++[B9TX25_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i32 {ECO:0000313|EMBL:ACB88911.1};+++[B9TX26_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX27_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i34 {ECO:0000313|EMBL:ACB88913.1};+++[B9TX28_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i35 {ECO:0000313|EMBL:ACB88914.1};+++[K7EKS6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[K7EKX2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465823};+++[K7EKX6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465827}; Flags: Fragment;+++[U3KQ43_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[U3KQB4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;"]
[10026,"'PIGK'",542,396,431,456.333333333333,"01100///Metabolic pathways+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis",{"$nulls":3},"GO:0042765///GPI-anchor transamidase complex+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0003923///GPI-anchor transamidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0003756///protein disulfide isomerase activity+++GO:0016787///hydrolase activity+++GO:0034235///GPI anchor binding+++GO:0005515///protein binding","GO:0006508///proteolysis+++GO:0016255///attachment of GPI anchor to protein+++GO:0006506///GPI anchor biosynthetic process","phosphatidylinositol glycan anchor biosynthesis class K","[GPI8_HUMAN|Reviewed]RecName: Full=GPI-anchor transamidase; Short=GPI transamidase; EC=3.-.-.-; AltName: Full=GPI8 homolog; Short=hGPI8; AltName: Full=Phosphatidylinositol-glycan biosynthesis class K protein; Short=PIG-K; Flags: Precursor;+++[A6NEM5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000352041};+++[B1AK81_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000388854}; SubName: Full=Phosphatidylinositol glycan, class K, isoform CRA_c {ECO:0000313|EMBL:EAX06382.1};+++[S4R3M5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000474518}; Flags: Fragment;"]
[100271715,"'ARHGEF33'",5,6,2,4.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0035023///regulation of Rho protein signal transduction","Rho guanine nucleotide exchange factor 33","[ARG33_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 33;+++[H7C1C9_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 33 {ECO:0000313|Ensembl:ENSP00000399688};"]
[100271849,"'MEF2B'",61.6,76.45,31.11,56.3866666666667,"04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway","H01613///Follicular lymphoma",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0042826///histone deacetylase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007517///muscle organ development","myocyte enhancer factor 2B","[MEF2B_HUMAN|Reviewed]RecName: Full=Myocyte-specific enhancer factor 2B; AltName: Full=RSRFR2; AltName: Full=Serum response factor-like protein 2;+++[A0A024R7K5_HUMAN|Unreviewed]SubName: Full=MADS box transcription enhancer factor 2, polypeptide B (Myocyte enhancer factor 2B), isoform CRA_a {ECO:0000313|EMBL:EAW84793.1};+++[B3KQ23_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386480}; SubName: Full=cDNA FLJ32648 fis, clone SYNOV2001451, highly similar to MYOCYTE-SPECIFIC ENHANCER FACTOR 2B {ECO:0000313|EMBL:BAG51885.1};+++[B8ZZJ5_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386784};+++[C9J4J4_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386374};"]
[100271927,"'RASA4B'",148.3,139.65,120.74,136.23,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0005543///phospholipid binding+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0071277///cellular response to calcium ion+++GO:0043087///regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction","RAS p21 protein activator 4B","[RAS4B_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4B;+++[F5GXT2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000440982};+++[F8W6L0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000303968};"]
[100272147,"'CMC4'",179.82,163.39,117.8,153.67,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0032991///protein-containing complex","GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0008283///cell proliferation","C-X9-C motif containing 4","[CMC4_HUMAN|Reviewed]RecName: Full=Cx9C motif-containing protein 4; AltName: Full=Mature T-cell proliferation 1 neighbor protein; AltName: Full=Mature T-cell proliferation-1 type A; Short=MTCP-1 type A; AltName: Full=Protein p8 MTCP-1; Short=p8MTCP1;+++[A0A0G2JKI4_HUMAN|Unreviewed]SubName: Full=Protein p13 MTCP-1 {ECO:0000313|Ensembl:ENSP00000427132}; Flags: Fragment;+++[Q9NRK3_HUMAN|Unreviewed]SubName: Full=p8 protein {ECO:0000313|EMBL:AAF76750.1};"]
[100287036,"'LOC100287036'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol",null,"GO:0060325///face morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001894///tissue homeostasis+++GO:0035264///multicellular organism growth+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0060348///bone development","uncharacterized LOC100287036","[B7Z1S9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59013 {ECO:0000313|EMBL:BAH11615.1};"]
[100287045,"'FAM90A26'",2.99,0,0,0.996666666666667,{"$nulls":7},"family with sequence similarity 90 member A26","[F90AP_HUMAN|Reviewed]RecName: Full=Putative protein FAM90A26 {ECO:0000305};"]
[100287171,"'WASHC1'",3908,5309,4881,4699.33333333333,"04212///Longevity regulating pathway - worm+++04144///Endocytosis",{"$nulls":3},"GO:0071203///WASH complex+++GO:0005814///centriole+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005829///cytosol+++GO:0071437///invadopodium+++GO:0055038///recycling endosome membrane+++GO:0000145///exocyst+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005856///cytoskeleton+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005776///autophagosome+++GO:0031410///cytoplasmic vesicle","GO:0043014///alpha-tubulin binding+++GO:0003779///actin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0015031///protein transport+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0010507///negative regulation of autophagy+++GO:0030335///positive regulation of cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0006887///exocytosis+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031396///regulation of protein ubiquitination+++GO:0022617///extracellular matrix disassembly+++GO:0042147///retrograde transport, endosome to Golgi+++GO:1990126///retrograde transport, endosome to plasma membrane","WASH complex subunit 1","[WASH1_HUMAN|Reviewed]RecName: Full=WASH complex subunit 1 {ECO:0000312|HGNC:HGNC:24361}; AltName: Full=CXYorf1-like protein on chromosome 9; AltName: Full=Protein FAM39E; AltName: Full=WAS protein family homolog 1;+++[A0A2R8YDD3_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 1 {ECO:0000313|Ensembl:ENSP00000494459}; Flags: Fragment;+++[A9QQ12_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71499.1}; Flags: Fragment;+++[A9QQ13_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71500.1}; Flags: Fragment;+++[A9QQ14_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71501.1}; Flags: Fragment;+++[A9QQ15_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71502.1}; Flags: Fragment;+++[A9QQ16_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71503.1}; Flags: Fragment;+++[A9QQ17_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71504.1}; Flags: Fragment;+++[A9QQ18_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71505.1}; Flags: Fragment;+++[A9QQ19_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71506.1}; Flags: Fragment;+++[A9QQ20_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71507.1}; Flags: Fragment;+++[A9QQ21_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71508.1}; Flags: Fragment;+++[A9QQ22_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71509.1}; Flags: Fragment;+++[A9QQ23_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71510.1}; Flags: Fragment;"]
[100287387,"'LOC100287387'",1,2,0,1,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0003677///DNA binding+++GO:0046983///protein dimerization activity","GO:0043066///negative regulation of apoptotic process+++GO:0006351///transcription, DNA-templated+++GO:0030335///positive regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045668///negative regulation of osteoblast differentiation","uncharacterized LOC100287387","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[TWIST_XENLA|diamond]RecName: Full=Twist-related protein; AltName: Full=T18; AltName: Full=X-twist;+++[TWST1_EULFU|diamond]RecName: Full=Twist-related protein 1;+++[TWST2_HUMAN|diamond]RecName: Full=Twist-related protein 2; AltName: Full=Class A basic helix-loop-helix protein 39; Short=bHLHa39; AltName: Full=Dermis-expressed protein 1; Short=Dermo-1;+++[TWST2_MOUSE|diamond]RecName: Full=Twist-related protein 2; AltName: Full=Dermis-expressed protein 1; Short=Dermo-1;+++[TWST2_RAT|diamond]RecName: Full=Twist-related protein 2;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100287482,"'SMKR1'",17,14,12,14.3333333333333,{"$nulls":7},"small lysine rich protein 1","[SMKR1_HUMAN|Reviewed]RecName: Full=Small lysine-rich protein 1;"]
[100287896,"'LOC100287896'",48,78,57,61,"04140///Autophagy - animal+++00785///Lipoic acid metabolism+++04137///Mitophagy - animal+++01100///Metabolic pathways",null,null,"R07769///lipoyl-[acp]:protein N6-lipoyltransferase Lipoyl-[acp] + Apoprotein <=> Protein N6-(lipoyl)lysine + Acyl-carrier protein+++R07766///octanoyl-[acp]:protein N6-octanoyltransferase Octanoyl-[acp] + Apoprotein <=> Protein N6-(octanoyl)lysine + Acyl-carrier protein","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0033819///lipoyl(octanoyl) transferase activity+++GO:0016874///ligase activity+++GO:0102555///octanoyl transferase activity (acting on glycine-cleavage complex H protein)","GO:0009249///protein lipoylation+++GO:0034641///cellular nitrogen compound metabolic process+++GO:2000376///positive regulation of oxygen metabolic process","uncharacterized LOC100287896","[Q8TB74_HUMAN|Unreviewed]SubName: Full=Similar to Cytochrome c, somatic {ECO:0000313|EMBL:AAH19340.1};"]
[100287898,"'TTC34'",7,28,14,16.3333333333333,{"$nulls":7},"tetratricopeptide repeat domain 34","[TTC34_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 34; Short=TPR repeat protein 34;+++[A0A1C7CYW7_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 34 {ECO:0000313|Ensembl:ENSP00000383873};"]
[100287932,"'TIMM23'",723.96,600.85,597.29,640.7,"04212///Longevity regulating pathway - worm","H00032///Thyroid cancer",null,null,"GO:0016021///integral component of membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031305///integral component of mitochondrial inner membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport","translocase of inner mitochondrial membrane 23","[TIM23_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim23;+++[Q6X2S9_HUMAN|Unreviewed]SubName: Full=Translocase of the inner mitochondrial membrane {ECO:0000313|EMBL:AAP83315.1}; Flags: Fragment;"]
[100288142,"'NBPF20'",491.75,609.05,450.59,517.13,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0003723///RNA binding",null,"NBPF member 20","[NBPFK_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 20;+++[A0A075B7A3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000471335};+++[A0A087WU97_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000478481};+++[H7BY70_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000358380};"]
[100288332,"'NPIPA5'",302.38,317.15,291.18,303.57,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"nuclear pore complex interacting protein family member A5","[NPIA5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[A0A067ZUK6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28873.1}; Flags: Fragment;+++[A0A067ZUK7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28878.1}; Flags: Fragment;+++[A0A067ZUK9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28883.1}; Flags: Fragment;+++[A0A067ZUL0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28888.1}; Flags: Fragment;+++[A0A067ZUL2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28893.1}; Flags: Fragment;+++[A0A067ZUL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28898.1}; Flags: Fragment;+++[A0A067ZUL5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28903.1}; Flags: Fragment;+++[A0A067ZUL6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28908.1}; Flags: Fragment;+++[A0A067ZUL8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28913.1}; Flags: Fragment;+++[A0A067ZVG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28875.1}; Flags: Fragment;+++[A0A067ZVG5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28880.1}; Flags: Fragment;+++[A0A067ZVG8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28885.1}; Flags: Fragment;+++[A0A067ZVH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28890.1}; Flags: Fragment;+++[A0A067ZVH5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28895.1}; Flags: Fragment;+++[A0A067ZVH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28900.1}; Flags: Fragment;+++[A0A067ZVI1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28905.1}; Flags: Fragment;+++[A0A067ZVI6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28910.1}; Flags: Fragment;+++[A0A067ZWN6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28874.1}; Flags: Fragment;+++[A0A067ZWN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28879.1}; Flags: Fragment;+++[A0A067ZWP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28884.1}; Flags: Fragment;+++[A0A067ZWP4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28889.1}; Flags: Fragment;+++[A0A067ZWP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28894.1}; Flags: Fragment;+++[A0A067ZWQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28899.1}; Flags: Fragment;+++[A0A067ZWQ3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28904.1}; Flags: Fragment;+++[A0A067ZWQ8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28909.1}; Flags: Fragment;+++[A0A067ZWR0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28914.1}; Flags: Fragment;+++[A0A067ZXG0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28872.1}; Flags: Fragment;+++[A0A067ZXG1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28877.1}; Flags: Fragment;+++[A0A067ZXG4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28882.1}; Flags: Fragment;+++[A0A067ZXG6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28887.1}; Flags: Fragment;+++[A0A067ZXG7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28892.1}; Flags: Fragment;+++[A0A067ZXH0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28897.1}; Flags: Fragment;+++[A0A067ZXH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28902.1}; Flags: Fragment;+++[A0A067ZXH4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28907.1}; Flags: Fragment;+++[A0A067ZXH7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28912.1}; Flags: Fragment;+++[A0A067ZXH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28917.1}; Flags: Fragment;+++[A0A067ZXM6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28876.1}; Flags: Fragment;+++[A0A067ZXN0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28881.1}; Flags: Fragment;+++[A0A067ZXN4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28886.1}; Flags: Fragment;+++[A0A067ZXN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28891.1}; Flags: Fragment;+++[A0A067ZXP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28896.1}; Flags: Fragment;+++[A0A067ZXP5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28901.1}; Flags: Fragment;+++[A0A067ZXP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28906.1}; Flags: Fragment;+++[A0A067ZXQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28911.1}; Flags: Fragment;+++[A0A0B4J1W7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000389275};+++[A0A0J9YW65_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000487831}; Flags: Fragment;+++[A0A0J9YWV6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000488135};+++[E9PJ88_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435611};+++[H0YED6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435610}; Flags: Fragment;+++[H0YEP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000436257}; Flags: Fragment;+++[H0YF59_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000437314}; Flags: Fragment;+++[Q9NRE7_HUMAN|Unreviewed]SubName: Full=KIAA0220-like protein {ECO:0000313|EMBL:AAF82267.1}; SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000330634};"]
[100288413,"'ERVMER34-1'",116,74,81,90.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region",null,null,"endogenous retrovirus group MER34 member 1, envelope","[MER34_HUMAN|Reviewed]RecName: Full=Endogenous retroviral envelope protein HEMO {ECO:0000305}; AltName: Full=Endogenous retrovirus group MER34 member 1 Env polyprotein {ECO:0000305}; AltName: Full=HERV-MER_4q12 provirus ancestral Env polyprotein; AltName: Full=Human endogenous MER34 (medium-reiteration-frequency-family-34) open reading frame {ECO:0000303|PubMed:28739914}; AltName: Full=Human endogenous MER34 ORF {ECO:0000303|PubMed:28739914}; Short=HEMO {ECO:0000303|PubMed:28739914}; Contains: RecName: Full=Endogenous retroviral envelope protein HEMO, secreted form {ECO:0000305}; AltName: Full=Endogenous retroviral envelope protein HEMO, 48 kDa form; Flags: Precursor;"]
[100288520,"'USP17L15'",0,4,0,1.33333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum","GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008234///cysteine-type peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0016787///hydrolase activity","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0042981///regulation of apoptotic process","ubiquitin specific peptidase 17-like family member 15","[U17LF_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 15; EC=3.4.19.12;+++[A0A087WUW7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 15 {ECO:0000313|Ensembl:ENSP00000483519};"]
[100288695,"'LIMS4'",24.89,15.41,38.74,26.3466666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0045216///cell-cell junction organization","LIM zinc finger domain containing 4","[LIMS3_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 3; AltName: Full=Particularly interesting new Cys-His protein 3; Short=PINCH-3;+++[LIMS4_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 4; AltName: Full=LIM and senescent cell antigen-like-containing domain protein 3-like;+++[A0A0J9YXC7_HUMAN|Unreviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein {ECO:0000256|PIRNR:PIRNR038003};"]
[100288960,"'PRSS43'",0,1,3,1.33333333333333,"04137///Mitophagy - animal+++05410///Hypertrophic cardiomyopathy (HCM)+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04140///Autophagy - animal+++04260///Cardiac muscle contraction","H00292///Hypertrophic cardiomyopathy (HCM)",null,null,"GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006508///proteolysis","serine protease 43","[PRS43_HUMAN|Reviewed]RecName: Full=Putative inactive serine protease 43 {ECO:0000305}; Flags: Precursor;"]
[100289187,"'TMEM225B'",4.17,3.39,5,4.18666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0010923///negative regulation of phosphatase activity","transmembrane protein 225B","[T225B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 225B {ECO:0000312|HGNC:HGNC:53075};"]
[100289279,"'CNTNAP3C'",89.11,78.81,67.16,78.36,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region",null,"GO:0008037///cell recognition+++GO:0007155///cell adhesion","contactin associated protein like 3C","[CNT3B_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3B; AltName: Full=Cell recognition molecule Caspr3b; Flags: Precursor;+++[CNTP3_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3; AltName: Full=Cell recognition molecule Caspr3; Flags: Precursor;+++[CNTP4_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP4_MOUSE|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP5_CHICK|diamond]RecName: Full=Contactin-associated protein-like 5; AltName: Full=Cell recognition molecule Caspr5; Flags: Precursor;"]
[100289561,"'LOC100289561'",92.41,118.33,127.44,112.726666666667,{"$nulls":4},"GO:0032389///MutLalpha complex","GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding","GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0006298///mismatch repair+++GO:0006355///regulation of transcription, DNA-templated","uncharacterized LOC100289561","[PM2P3_HUMAN|diamond]RecName: Full=Putative postmeiotic segregation increased 2-like protein 3; AltName: Full=PMS2-related protein 3; AltName: Full=Postmeiotic segregation increased 2-like protein 9; AltName: Full=Postmeiotic segregation increased protein 5; AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 3;+++[RBAK_HUMAN|diamond]RecName: Full=RB-associated KRAB zinc finger protein; AltName: Full=RB-associated KRAB repressor; Short=hRBaK; AltName: Full=Zinc finger protein 769;+++[ZN510_HUMAN|diamond]RecName: Full=Zinc finger protein 510;+++[ZNF12_HUMAN|diamond]RecName: Full=Zinc finger protein 12; AltName: Full=Gonadotropin-inducible ovary transcription repressor 3; Short=GIOT-3; AltName: Full=Zinc finger protein 325; AltName: Full=Zinc finger protein KOX3;+++[ZNF12_MOUSE|diamond]RecName: Full=Zinc finger protein 12;"]
[100289635,"'ZNF605'",293,371,305,323,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 605","[ZN605_HUMAN|Reviewed]RecName: Full=Zinc finger protein 605;+++[Q8WW51_HUMAN|Unreviewed]SubName: Full=ZNF605 protein {ECO:0000313|EMBL:AAH20877.1}; Flags: Fragment;"]
[100289678,"'ZNF783'",246,254,271,257,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger family member 783","[ZN783_HUMAN|Reviewed]RecName: Full=Protein ZNF783;"]
[100293516,"'ZNF587B'",47.95,66.69,52.89,55.8433333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 587B","[Z587B_HUMAN|Reviewed]RecName: Full=Zinc finger protein 587B;+++[M0QY62_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000469623};+++[M0R1N2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000472004}; Flags: Fragment;"]
[100293534,"'C4B_2'",439.6,592.09,557.91,529.866666666667,"05150///Staphylococcus aureus infection+++05322///Systemic lupus erythematosus+++05133///Pertussis+++04610///Complement and coagulation cascades","H00102///Classic complement pathway component defects+++H00080///Systemic lupus erythematosus+++H01649///Schizophrenia",null,null,"GO:0030054///cell junction+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0072562///blood microparticle+++GO:0043025///neuronal cell body+++GO:0005886///plasma membrane+++GO:0044216///other organism cell","GO:0001848///complement binding+++GO:0030246///carbohydrate binding+++GO:0004252///serine-type endopeptidase activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0001849///complement component C1q binding","GO:2000427///positive regulation of apoptotic cell clearance+++GO:0043687///post-translational protein modification+++GO:0008228///opsonization+++GO:0030449///regulation of complement activation+++GO:0032490///detection of molecule of bacterial origin+++GO:0044267///cellular protein metabolic process+++GO:0006954///inflammatory response+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response+++GO:0006956///complement activation","complement component 4B (Chido blood group), copy 2","[CO4B_HUMAN|Reviewed]RecName: Full=Complement C4-B; AltName: Full=Basic complement C4; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; Contains: RecName: Full=Complement C4 beta chain; Contains: RecName: Full=Complement C4-B alpha chain; Contains: RecName: Full=C4a anaphylatoxin; Contains: RecName: Full=C4b-B; Contains: RecName: Full=C4d-B; Contains: RecName: Full=Complement C4 gamma chain; Flags: Precursor;+++[A0A0G2JL54_HUMAN|Unreviewed]SubName: Full=Complement C4-B {ECO:0000313|Ensembl:ENSP00000449433};"]
[100302652,"'GPR75-ASB3'",62.32,93.38,86.48,80.7266666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0035556///intracellular signal transduction+++GO:0016567///protein ubiquitination","GPR75-ASB3 readthrough","[ASB3_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 3; Short=ASB-3;+++[A0A0A6YYF3_HUMAN|Unreviewed]SubName: Full=Protein GPR75-ASB3 {ECO:0000313|Ensembl:ENSP00000385085};"]
[100302736,"'TMED7-TICAM2'",56.34,38.51,54.59,49.8133333333333,"05161///Hepatitis B+++04620///Toll-like receptor signaling pathway+++05133///Pertussis+++04064///NF-kappa B signaling pathway+++04217///Necroptosis",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030134///COPII-coated ER to Golgi transport vesicle","GO:0005543///phospholipid binding","GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization","TMED7-TICAM2 readthrough","[TCAM2_HUMAN|Reviewed]RecName: Full=TIR domain-containing adapter molecule 2; Short=TICAM-2; AltName: Full=Putative NF-kappa-B-activating protein 502; AltName: Full=TRIF-related adapter molecule; AltName: Full=Toll-like receptor adaptor protein 3; AltName: Full=Toll/interleukin-1 receptor domain-containing protein; Short=MyD88-4;+++[TMED7_HUMAN|Reviewed]RecName: Full=Transmembrane emp24 domain-containing protein 7; AltName: Full=p24 family protein gamma-3; Short=p24gamma3; AltName: Full=p27; Flags: Precursor;+++[A0A0A6YYA0_HUMAN|Unreviewed]SubName: Full=Protein TMED7-TICAM2 {ECO:0000313|Ensembl:ENSP00000333650};"]
[100303755,"'PET117'",69.72,67.66,78.7,72.0266666666667,{"$nulls":4},"GO:0005739///mitochondrion","GO:0004402///histone acetyltransferase activity+++GO:0030274///LIM domain binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","PET117 homolog","[PT117_HUMAN|Reviewed]RecName: Full=Protein PET117 homolog, mitochondrial; Flags: Precursor;+++[L0R6F6_HUMAN|Unreviewed]SubName: Full=Alternative protein CSRP2BP {ECO:0000313|EMBL:CCO13715.1};"]
[100310812,"'SPDYE2B'",1,4.63,3,2.87666666666667,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",null,null,"GO:0005737///cytoplasm+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane+++GO:0005829///cytosol","GO:0019901///protein kinase binding","GO:0046580///negative regulation of Ras protein signal transduction+++GO:0034260///negative regulation of GTPase activity+++GO:0045859///regulation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0071277///cellular response to calcium ion","speedy/RINGO cell cycle regulator family member E2B","[SPE2B_HUMAN|Reviewed]RecName: Full=Speedy protein E2B;"]
[100310846,"'ANKRD61'",1,0,1,0.666666666666667,{"$nulls":7},"ankyrin repeat domain 61","[ANR61_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 61;"]
[100316904,"'SAP25'",20,43,24,29,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0006355///regulation of transcription, DNA-templated","Sin3A associated protein 25","[SAP25_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP25; AltName: Full=25 kDa Sin3-associated polypeptide; AltName: Full=Sin3 corepressor complex subunit SAP25;+++[A0A087WYF9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP25 {ECO:0000313|Ensembl:ENSP00000481773};"]
[10036,"'CHAF1A'",150,159,158,155.666666666667,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0033186///CAF-1 complex","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0070087///chromo shadow domain binding+++GO:0051082///unfolded protein binding+++GO:0003682///chromatin binding","GO:0031497///chromatin assembly+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006334///nucleosome assembly+++GO:0007049///cell cycle","chromatin assembly factor 1 subunit A","[CAF1A_HUMAN|Reviewed]RecName: Full=Chromatin assembly factor 1 subunit A; Short=CAF-1 subunit A; AltName: Full=Chromatin assembly factor I p150 subunit; Short=CAF-I 150 kDa subunit; Short=CAF-I p150; Short=hp150;+++[D6W625_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1, subunit A (P150), isoform CRA_a {ECO:0000313|EMBL:EAW69225.1};+++[K7EJF1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000465142}; Flags: Fragment;+++[K7EME9_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466475}; Flags: Fragment;+++[K7ENC7_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466888}; Flags: Fragment;+++[K7EPA1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000467296}; Flags: Fragment;"]
[10038,"'PARP2'",330,293,255,292.666666666667,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04210///Apoptosis+++04212///Longevity regulating pathway - worm",null,"M00296///BER complex",null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990404///protein ADP-ribosylase activity","GO:0006471///protein ADP-ribosylation+++GO:0006281///DNA repair+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0018312///peptidyl-serine ADP-ribosylation+++GO:1901215///negative regulation of neuron death","poly(ADP-ribose) polymerase 2","[PARP2_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 2; Short=PARP-2; Short=hPARP-2; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 2; Short=ARTD2; AltName: Full=NAD(+) ADP-ribosyltransferase 2; Short=ADPRT-2; AltName: Full=Poly[ADP-ribose] synthase 2; Short=pADPRT-2;+++[E9PJ27_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 2 {ECO:0000313|Ensembl:ENSP00000431867};+++[G3V167_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[H0YH02_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114}; Flags: Fragment;"]
[100381270,"'ZBED6'",102,124,130,118.666666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger BED-type containing 6","[ZBED6_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 6 {ECO:0000303|PubMed:20016685};"]
[10039,"'PARP3'",411,463,405,426.333333333333,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04212///Longevity regulating pathway - worm+++04210///Apoptosis",null,"M00296///BER complex",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0005815///microtubule organizing center+++GO:0005730///nucleolus+++GO:0005814///centriole+++GO:0005856///cytoskeleton","GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003824///catalytic activity+++GO:0016740///transferase activity","GO:0051106///positive regulation of DNA ligation+++GO:0060236///regulation of mitotic spindle organization+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0006281///DNA repair+++GO:1905662///negative regulation of telomerase RNA reverse transcriptase activity+++GO:0000723///telomere maintenance+++GO:0006471///protein ADP-ribosylation+++GO:1990166///protein localization to site of double-strand break","poly(ADP-ribose) polymerase family member 3","[PARP3_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 3; Short=PARP-3; Short=hPARP-3; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 3; Short=ARTD3; AltName: Full=IRT1; AltName: Full=NAD(+) ADP-ribosyltransferase 3; Short=ADPRT-3; AltName: Full=Poly[ADP-ribose] synthase 3; Short=pADPRT-3;+++[A0A024R2X5_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[C9J9C7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417625}; Flags: Fragment;+++[F8WAY7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417396};"]
[1004,"'CDH6'",157,127.47,175,153.156666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0009986///cell surface+++GO:0016342///catenin complex+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0034332///adherens junction organization","cadherin 6","[CADH6_HUMAN|Reviewed]RecName: Full=Cadherin-6; AltName: Full=Kidney cadherin; Short=K-cadherin; Flags: Precursor;+++[D6RF86_HUMAN|Unreviewed]SubName: Full=Cadherin-6 {ECO:0000313|Ensembl:ENSP00000424843};+++[L8EAC6_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH6 {ECO:0000313|EMBL:CCQ43288.1};"]
[10040,"'TOM1L1'",585,631,609,608.333333333333,"04714///Thermogenesis+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++04137///Mitophagy - animal+++04140///Autophagy - animal",null,"M00154///Cytochrome c oxidase",null,"GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005623///cell+++GO:0005795///Golgi stack+++GO:0005768///endosome+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0043130///ubiquitin binding+++GO:0005515///protein binding+++GO:0030295///protein kinase activator activity+++GO:0017124///SH3 domain binding","GO:0006886///intracellular protein transport+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:2000278///regulation of DNA biosynthetic process+++GO:0015031///protein transport+++GO:0031954///positive regulation of protein autophosphorylation","target of myb1 like 1 membrane trafficking protein","[TM1L1_HUMAN|Reviewed]RecName: Full=TOM1-like protein 1; AltName: Full=Src-activating and signaling molecule protein; AltName: Full=Target of Myb-like protein 1;+++[I3L0N2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458219};+++[I3L1G1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458809}; Flags: Fragment;+++[I3L1Q1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459003}; Flags: Fragment;+++[I3L1T2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459079};+++[I3L367_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460213}; Flags: Fragment;+++[I3L3M3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460565};+++[I3L3T4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460721};+++[I3L4G0_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461215}; Flags: Fragment;+++[I3L4I4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461284};+++[I3L4N3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461396}; Flags: Fragment;+++[I3NI44_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461876};+++[J3KQU4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000408958}; SubName: Full=Target of myb1-like 1 (Chicken), isoform CRA_b {ECO:0000313|EMBL:EAW94552.1};+++[K7EP47_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000467227}; Flags: Fragment;+++[Q8NI65_HUMAN|Unreviewed]SubName: Full=OK/KNS-CL.3 {ECO:0000313|EMBL:BAB93522.1};"]
[10042,"'HMGXB4'",308,284,283,291.666666666667,{"$nulls":4},"GO:0016589///NURF complex+++GO:0005634///nucleus","GO:0003677///DNA binding","GO:0016055///Wnt signaling pathway+++GO:0008333///endosome to lysosome transport+++GO:0030178///negative regulation of Wnt signaling pathway","HMG-box containing 4","[HMGX4_HUMAN|Reviewed]RecName: Full=HMG domain-containing protein 4; AltName: Full=HMG box-containing protein 4; AltName: Full=High mobility group protein 2-like 1; AltName: Full=Protein HMGBCG;+++[B0QXZ8_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000415500}; Flags: Fragment;+++[B0QXZ9_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000401658}; Flags: Fragment;+++[F8WDU7_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000395532};+++[Q2M3X1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI04757.1}; SubName: Full=High-mobility group protein 2-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW60048.1};+++[Q2T9L2_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI11374.1}; Flags: Fragment;+++[Q6P681_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH62413.1}; Flags: Fragment;+++[Q6PJ09_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH25303.1}; Flags: Fragment;+++[Q6PJC1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH17326.1}; Flags: Fragment;+++[Q7Z641_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH52624.1}; Flags: Fragment;"]
[10043,"'TOM1'",1827,2083,1794,1901.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0005769///early endosome+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005623///cell+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0035577///azurophil granule membrane","GO:0030276///clathrin binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0043312///neutrophil degranulation+++GO:0016197///endosomal transport+++GO:0006897///endocytosis","target of myb1 membrane trafficking protein","[TOM1_HUMAN|Reviewed]RecName: Full=Target of Myb protein 1;+++[B0QY01_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000393714}; Flags: Fragment;+++[B0QY02_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000389789}; Flags: Fragment;+++[B3KUF5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39747 fis, clone SMINT2017432, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53417.1};+++[B3KUU1_HUMAN|Unreviewed]SubName: Full=Target of myb1 (Chicken), isoform CRA_a {ECO:0000313|EMBL:EAW60053.1}; SubName: Full=cDNA FLJ40607 fis, clone THYMU2012273, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53553.1};+++[F8WAW7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000385906};+++[F8WB30_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000397492};+++[F8WBB0_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000390429};+++[F8WE29_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000394944};+++[H7BYN7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000379085};+++[Q6UW50_HUMAN|Unreviewed]SubName: Full=TOM1 {ECO:0000313|EMBL:AAQ89339.1}; SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000371465};+++[V9GYF4_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000476698}; Flags: Fragment;+++[V9GZ68_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000477471}; Flags: Fragment;"]
[10044,"'SH2D3C'",15,8,10,11,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0098793///presynapse+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004102///choline O-acetyltransferase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005070///SH3/SH2 adaptor activity","GO:0007254///JNK cascade+++GO:0007269///neurotransmitter secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0008292///acetylcholine biosynthetic process+++GO:0009967///positive regulation of signal transduction+++GO:0007274///neuromuscular synaptic transmission+++GO:0007264///small GTPase mediated signal transduction+++GO:0042136///neurotransmitter biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process","SH2 domain containing 3C","[SH2D3_HUMAN|Reviewed]RecName: Full=SH2 domain-containing protein 3C; AltName: Full=Novel SH2-containing protein 3; AltName: Full=SH2 domain-containing Eph receptor-binding protein 1; Short=SHEP1;+++[A0A1W2PP46_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000491328};+++[A0A1W2PRG4_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000492646};+++[B4DG32_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59318, highly similar to SH2 domain-containing protein 3C {ECO:0000313|EMBL:BAG57643.1};+++[H0Y5X5_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3C {ECO:0000313|Ensembl:ENSP00000401641}; Flags: Fragment;+++[Q5JU32_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3C {ECO:0000313|Ensembl:ENSP00000413760}; Flags: Fragment;+++[R4GN13_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000473443};"]
[10045,"'SH2D3A'",40,35,41,38.6666666666667,"04910///Insulin signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0005622///intracellular+++GO:0005764///lysosome+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0005794///Golgi apparatus+++GO:0001891///phagocytic cup","GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005070///SH3/SH2 adaptor activity","GO:0007254///JNK cascade+++GO:0007264///small GTPase mediated signal transduction+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0009967///positive regulation of signal transduction","SH2 domain containing 3A","[SH23A_HUMAN|Reviewed]RecName: Full=SH2 domain-containing protein 3A; AltName: Full=Novel SH2-containing protein 1;+++[A8K2M8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78700, highly similar to Homo sapiens SH2 domain containing 3A, mRNA {ECO:0000313|EMBL:BAF82982.1};+++[M0QZQ6_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000470700}; Flags: Fragment;"]
[10046,"'MAMLD1'",529,669,585,594.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00609///46,XY disorders of sex development (Other)",null,null,"GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008584///male gonad development","mastermind like domain containing 1","[MAMD1_HUMAN|Reviewed]RecName: Full=Mastermind-like domain-containing protein 1; AltName: Full=F18; AltName: Full=Protein CG1;+++[F8WAK3_HUMAN|Unreviewed]SubName: Full=Mastermind-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000351765}; Flags: Fragment;+++[L0R6K4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAMLD1 {ECO:0000313|EMBL:CCO13767.1};"]
[100462977,"'MTRNR2L1'",3101.12,2448.46,3062.03,2870.53666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 1","[HMN1_HUMAN|Reviewed]RecName: Full=Humanin-like 1 {ECO:0000305}; Short=HN1 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 1 {ECO:0000312|HGNC:HGNC:37155};"]
[100462981,"'MTRNR2L2'",138131.59,146332.66,180297.73,154920.66,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 2","[HMN2_HUMAN|Reviewed]RecName: Full=Humanin-like 2 {ECO:0000305}; Short=HN2 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 2 {ECO:0000312|HGNC:HGNC:37156};"]
[100462983,"'MTRNR2L3'",887.06,690.77,864.63,814.153333333333,"03013///RNA transport+++05164///Influenza A",null,"M00427///Nuclear pore complex",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 3","[HMN3_HUMAN|Reviewed]RecName: Full=Humanin-like 3 {ECO:0000305}; Short=HN3 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 3 {ECO:0000312|HGNC:HGNC:37157};"]
[100463289,"'MTRNR2L5'",3,0,0,1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0003674///molecular_function+++GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:1900118///negative regulation of execution phase of apoptosis+++GO:0072734///cellular response to staurosporine","MT-RNR2 like 5","[HMN5_HUMAN|Reviewed]RecName: Full=Humanin-like 5 {ECO:0000305}; Short=HN5 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 5 {ECO:0000312|HGNC:HGNC:37162};"]
[100463482,"'MTRNR2L6'",734.34,573.07,787.92,698.443333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 6","[HMN6_HUMAN|Reviewed]RecName: Full=Humanin-like 6 {ECO:0000305}; Short=HN6 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 6 {ECO:0000312|HGNC:HGNC:37163};"]
[100463486,"'MTRNR2L8'",79110.97,85344.71,107167.25,90540.9766666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","MT-RNR2 like 8","[HMN8_HUMAN|Reviewed]RecName: Full=Humanin-like 8 {ECO:0000305}; Short=HN8 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 8 {ECO:0000312|HGNC:HGNC:37165};"]
[100463487,"'MTRNR2L9'",1308.28,1159.76,1438.1,1302.04666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 9","[HMN9_HUMAN|Reviewed]RecName: Full=Humanin-like 9 {ECO:0000305}; Short=HN9 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 9 {ECO:0000312|HGNC:HGNC:37166};"]
[100463488,"'MTRNR2L10'",486.64,424.59,514.35,475.193333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","MT-RNR2 like 10","[HMN10_HUMAN|Reviewed]RecName: Full=Humanin-like 10 {ECO:0000305}; Short=HN10 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 10 {ECO:0000312|HGNC:HGNC:37167};"]
[10048,"'RANBP9'",797,680,678,718.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex","GO:0019899///enzyme binding+++GO:0008536///Ran GTPase binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007020///microtubule nucleation+++GO:0007411///axon guidance+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000165///MAPK cascade","RAN binding protein 9","[RANB9_HUMAN|Reviewed]RecName: Full=Ran-binding protein 9; Short=RanBP9; AltName: Full=BPM-L; AltName: Full=BPM90; AltName: Full=Ran-binding protein M; Short=RanBPM {ECO:0000303|PubMed:11470507, ECO:0000303|PubMed:17467196}; AltName: Full=RanBP7;+++[A0A024QZW3_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_a {ECO:0000313|EMBL:EAW55345.1};+++[A0A024R014_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_b {ECO:0000313|EMBL:EAW55344.1};"]
[10049,"'DNAJB6'",1814,1585,1550,1649.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0031072///heat shock protein binding+++GO:0001671///ATPase activator activity+++GO:0042802///identical protein binding+++GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0060710///chorio-allantoic fusion+++GO:0032781///positive regulation of ATPase activity+++GO:1900034///regulation of cellular response to heat+++GO:0060715///syncytiotrophoblast cell differentiation involved in labyrinthine layer development+++GO:0090084///negative regulation of inclusion body assembly+++GO:0030198///extracellular matrix organization+++GO:0030036///actin cytoskeleton organization+++GO:0006457///protein folding+++GO:0045109///intermediate filament organization+++GO:0060717///chorion development+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated","DnaJ heat shock protein family (Hsp40) member B6","[DNJB6_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily B member 6; AltName: Full=HHDJ1; AltName: Full=Heat shock protein J2; Short=HSJ-2; AltName: Full=MRJ; AltName: Full=MSJ-1;+++[A0A0J9YX62_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000488263};+++[C9J2C4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000400665}; Flags: Fragment;+++[C9J2P2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000410643}; Flags: Fragment;+++[C9JB42_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000391690}; Flags: Fragment;+++[C9JDR7_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396240}; Flags: Fragment;+++[C9JDX6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000403407}; Flags: Fragment;+++[C9JN01_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000389599}; Flags: Fragment;+++[E9PH18_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396267};+++[F8WCZ4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000415201};+++[Q49A72_HUMAN|Unreviewed]SubName: Full=DNAJB6 protein {ECO:0000313|EMBL:AAH43270.1};+++[Q75MP3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DNAJB6 {ECO:0000313|EMBL:AAS07521.1}; Flags: Fragment;"]
[100499483,"'CCDC180'",146,155,113,138,{"$nulls":4},"GO:0070062///extracellular exosome",null,null,"coiled-coil domain containing 180","[CC180_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 180;+++[B4DZK1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50036, weakly similar to Myosin-11 {ECO:0000313|EMBL:BAG64113.1};"]
[1005,"'CDH7'",3,9,4,5.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0034332///adherens junction organization+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 7","[CADH7_HUMAN|Reviewed]RecName: Full=Cadherin-7; Flags: Precursor;+++[F5H5X9_HUMAN|Unreviewed]SubName: Full=Cadherin-7 {ECO:0000313|Ensembl:ENSP00000443030};+++[Q8IY78_HUMAN|Unreviewed]SubName: Full=CDH7 protein {ECO:0000313|EMBL:AAH36786.1};"]
[100505385,"'IQCJ-SCHIP1'",683.77,502.33,547.9,578,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0043194///axon initial segment+++GO:0030424///axon","GO:0005515///protein binding","GO:0051494///negative regulation of cytoskeleton organization","IQCJ-SCHIP1 readthrough","[IQIP1_HUMAN|Reviewed]RecName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000312|HGNC:HGNC:38842};+++[A0A1W2PP08_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491220}; Flags: Fragment;+++[A0A1W2PPY3_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491419}; Flags: Fragment;+++[A0A1W2PQT1_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492132}; Flags: Fragment;+++[A0A1W2PR78_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492358}; Flags: Fragment;+++[A0A1W2PR91_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492497}; Flags: Fragment;+++[A0A1W2PRV6_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492461}; Flags: Fragment;+++[A0A1W2PRY4_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492853}; Flags: Fragment;+++[C9J366_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000417305};"]
[100505549,"'LOC100505549'",2,5,9,5.33333333333333,{"$nulls":7},"uncharacterized LOC100505549","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100505573,"'INAFM2'",489,430,489,469.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005246///calcium channel regulator activity",null,"InaF motif containing 2","[INAM2_HUMAN|Reviewed]RecName: Full=Putative transmembrane protein INAFM2 {ECO:0000305}; AltName: Full=InaF-motif-containing protein 2 {ECO:0000312|HGNC:HGNC:35165}; AltName: Full=Osteogenesis up-regulated transcript 1 {ECO:0000303|PubMed:19531736};"]
[100505591,"'LRRC3C'",2,5,1,2.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space","GO:0043565///sequence-specific DNA binding+++GO:0004860///protein kinase inhibitor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0043312///neutrophil degranulation+++GO:0090156///cellular sphingolipid homeostasis+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0006672///ceramide metabolic process+++GO:1900060///negative regulation of ceramide biosynthetic process+++GO:0006351///transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0019221///cytokine-mediated signaling pathway","leucine rich repeat containing 3C","[LRR3C_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 3C; Flags: Precursor;"]
[100505679,"'UBE2Q2L'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031258///lamellipodium membrane+++GO:0070062///extracellular exosome+++GO:0005925///focal adhesion+++GO:0005796///Golgi lumen+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0043202///lysosomal lumen","GO:0019901///protein kinase binding","GO:0030206///chondroitin sulfate biosynthetic process+++GO:0048771///tissue remodeling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030207///chondroitin sulfate catabolic process+++GO:0035556///intracellular signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001525///angiogenesis+++GO:0000187///activation of MAPK activity+++GO:0008283///cell proliferation+++GO:0008347///glial cell migration","ubiquitin conjugating enzyme E2 Q2 like","[U2Q2L_HUMAN|Reviewed]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;"]
[100505741,"'SPATA1'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005764///lysosome","GO:0008061///chitin binding+++GO:0004568///chitinase activity","GO:0009313///oligosaccharide catabolic process+++GO:0006032///chitin catabolic process","spermatogenesis associated 1","[SPAT1_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 1; AltName: Full=Sperm-specific protein SP-2;"]
[100505767,"'SPDYE18'",2.81,1.62,3.52,2.65,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E18","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPDE7_HUMAN|diamond]RecName: Full=Putative speedy protein E7; AltName: Full=Speedy protein E7 pseudogene;+++[SPDL3_HUMAN|diamond]RecName: Full=Putative speedy protein-like protein 3;"]
[100505841,"'LOC100505841'",0,0,0.67,0.223333333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding",null,"zinc finger protein 474-like","[A0A1B0GTH9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000489710};+++[A0A1B0GW86_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490823}; Flags: Fragment;+++[A0A1B0GWJ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490947};"]
[100505876,"'CEBPZOS'",703,477.28,603.99,594.756666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","CEBPZ opposite strand","[CEBOS_HUMAN|Reviewed]RecName: Full=Protein CEBPZOS {ECO:0000305}; AltName: Full=CEBPZ antisense RNA 1 {ECO:0000312|HGNC:HGNC:49288}; AltName: Full=CEBPZ opposite strand {ECO:0000312|HGNC:HGNC:49288};"]
[100505989,"'SMIM31'",0.97,2,1.03,1.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"small integral membrane protein 31","[SIM31_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 31 {ECO:0000305};"]
[100505993,"'TMEM210'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 210","[TM210_HUMAN|Reviewed]RecName: Full=Transmembrane protein 210; Flags: Precursor;+++[H3BNS5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 210 {ECO:0000313|Ensembl:ENSP00000454984};"]
[100506012,"'PPP5D1'",22,21,16,19.6666666666667,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005622///intracellular","GO:0005509///calcium ion binding","GO:0019722///calcium-mediated signaling","PPP5 tetratricopeptide repeat domain containing 1","[PP5D1_HUMAN|Reviewed]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[A0A087WY80_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000481586}; Flags: Fragment;+++[M0R196_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000471730}; Flags: Fragment;"]
[100506084,"'ARL17B'",77.77,173.26,151.15,134.06,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport","ADP ribosylation factor like GTPase 17B","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[A8K0M5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76374 {ECO:0000313|EMBL:BAF82279.1};+++[I3L1A0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000458681}; Flags: Fragment;+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L2E4_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459606};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};+++[Q9BVU5_HUMAN|Unreviewed]SubName: Full=ARL17 protein {ECO:0000313|EMBL:AAH00924.2}; Flags: Fragment;"]
[100506115,"'SMIM25'",65,61,65,63.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"small integral membrane protein 25","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100506127,"'GVQW3'",87.69,116.48,95.01,99.7266666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding","GO:0008285///negative regulation of cell proliferation+++GO:0007165///signal transduction","GVQW motif containing 3","[GVQW3_HUMAN|Reviewed]RecName: Full=Protein GVQW3 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 3 {ECO:0000305};+++[A0A0U1RQW1_HUMAN|Unreviewed]SubName: Full=Protein GVQW3 {ECO:0000313|Ensembl:ENSP00000489195};"]
[100506144,"'TMEM35B'",185,238,212,211.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 35B","[TM35B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 35B; AltName: Full=ZMYM6 neighbor protein; Flags: Precursor;"]
[100506164,"'HSFX1'",8.58,10,19,12.5266666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0061408///positive regulation of transcription from RNA polymerase II promoter in response to heat stress+++GO:0006355///regulation of transcription, DNA-templated+++GO:0034605///cellular response to heat","heat shock transcription factor family, X-linked 1","[HSFX1_HUMAN|Reviewed]RecName: Full=Heat shock transcription factor, X-linked;+++[A0A140VK21_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 21 {ECO:0000313|EMBL:AEE61158.1};"]
[100506243,"'KRBOX1'",31,21,28,26.6666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","KRAB box domain containing 1","[KRBX1_HUMAN|Reviewed]RecName: Full=KRAB domain-containing protein 1;+++[A0A024R2N1_HUMAN|Unreviewed]SubName: Full=HCG2039480, isoform CRA_a {ECO:0000313|EMBL:EAW64687.1};"]
[100506248,"'PTMAP9'",745.86,1029.11,882.01,885.66,"05169///Epstein-Barr virus infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0042393///histone binding+++GO:0033613///activating transcription factor binding","GO:0043486///histone exchange+++GO:0006351///transcription, DNA-templated","prothymosin alpha pseudogene 9","[PTMA_BOVIN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_HUMAN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_MOUSE|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_PONAB|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_RAT|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;"]
[100506514,"'LOC100506514'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0005622///intracellular","GO:0005525///GTP binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity","GO:0006164///purine nucleotide biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process","uncharacterized LOC100506514","[ZKSC2_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 2; AltName: Full=Zinc finger protein 694;+++[ZSC20_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31; AltName: Full=Zinc finger protein 360; AltName: Full=Zinc finger protein KOX29;+++[ZSC20_MOUSE|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31;+++[ZSC29_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 29; AltName: Full=Zinc finger protein 690;"]
[100506540,"'SPTY2D1OS'",0,3,0,1,"00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00010///Glycolysis / Gluconeogenesis+++01120///Microbial metabolism in diverse environments+++00640///Propanoate metabolism+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00620///Pyruvate metabolism+++04922///Glucagon signaling pathway","H01762///Muscle glycogen storage disease+++H00069///Glycogen storage diseases (GSD)+++H01946///Glycogen storage disease type XI",null,"R00703///(S)-Lactate:NAD+ oxidoreductase (S)-Lactate + NAD+ <=> Pyruvate + NADH + H++++R03104///3-Mercaptolactate:NAD+ oxidoreductase 3-Mercaptolactate + NAD+ <=> Mercaptopyruvate + NADH + H++++R01000///2-hydroxybutyrate:NAD+ oxidoreductase 2-Hydroxybutanoic acid + NAD+ <=> 2-Oxobutanoate + NADH + H+","GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0015031///protein transport+++GO:0006915///apoptotic process+++GO:0005975///carbohydrate metabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006464///cellular protein modification process+++GO:0043065///positive regulation of apoptotic process+++GO:0019752///carboxylic acid metabolic process","SPTY2D1 opposite strand","[SPTOS_HUMAN|Reviewed]RecName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000305}; AltName: Full=SPTY2D1 antisense RNA 1 {ECO:0000312|HGNC:HGNC:44122}; AltName: Full=SPTY2D1 opposite strand {ECO:0000312|HGNC:HGNC:44122};+++[A0A0U1RQQ8_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489122};+++[A0A0U1RQZ7_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489253};+++[A0A0U1RR47_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489337};"]
[100506564,"'THEGL'",12,5,6,7.66666666666667,{"$nulls":7},"theg spermatid protein like","[THEGL_HUMAN|Reviewed]RecName: Full=Testicular haploid expressed gene protein-like; AltName: Full=Theg spermatid-like protein;"]
[100506571,"'LOC100506571'",3,3,1,2.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100506571","[Q9NT86_HUMAN|Unreviewed]SubName: Full=HCG42237 {ECO:0000313|EMBL:EAW69830.1};"]
[100506581,"'C16orf95'",36,37,46,39.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"chromosome 16 open reading frame 95","[CP095_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C16orf95;+++[A0A087X224_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000484646};+++[H3BNZ7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000455079};"]
[100506658,"'OCLN'",117,131,116,121.333333333333,"04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++05160///Hepatitis C","H00840///Band-like calcification with simplified gyration and polymicrogyria (BLC-PMG)",null,null,"GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005911///cell-cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0005923///bicellular tight junction+++GO:0016327///apicolateral plasma membrane+++GO:0030139///endocytic vesicle+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0070673///response to interleukin-18+++GO:0045216///cell-cell junction organization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0065003///protein-containing complex assembly+++GO:2000810///regulation of bicellular tight junction assembly+++GO:0070830///bicellular tight junction assembly","occludin","[OCLN_HUMAN|Reviewed]RecName: Full=Occludin;+++[A0A0G2JMZ8_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};+++[A0A0G2JPF2_HUMAN|Unreviewed]SubName: Full=Occludin {ECO:0000313|Ensembl:ENSP00000483480};+++[A8K3T2_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};"]
[100507027,"'MRLN'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum","GO:0004857///enzyme inhibitor activity+++GO:0005179///hormone activity+++GO:0031788///motilin receptor binding","GO:1902081///negative regulation of calcium ion import into sarcoplasmic reticulum+++GO:0043086///negative regulation of catalytic activity+++GO:0009611///response to wounding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010469///regulation of signaling receptor activity","myoregulin","[MLN_HUMAN|Reviewed]RecName: Full=Myoregulin {ECO:0000303|PubMed:25640239};"]
[100507050,"'TPBGL'",2,2,2,2,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"trophoblast glycoprotein like","[TPBGL_HUMAN|Reviewed]RecName: Full=Trophoblast glycoprotein-like; Flags: Precursor;"]
[100507055,"'LRCOL1'",11,20,12,14.3333333333333,{"$nulls":4},"GO:0005576///extracellular region","GO:0008047///enzyme activator activity","GO:0043085///positive regulation of catalytic activity+++GO:0007586///digestion+++GO:0032094///response to food+++GO:0016042///lipid catabolic process","leucine rich colipase like 1","[LRCL1_HUMAN|Reviewed]RecName: Full=Leucine-rich colipase-like protein 1; Flags: Precursor;+++[A0A087WT69_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000477635};+++[A0A087WYD7_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000481713};+++[A0A087WZ94_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000482471};"]
[100507290,"'ZNF865'",1144,1322.01,1233.16,1233.05666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","zinc finger protein 865","[ZN865_HUMAN|Reviewed]RecName: Full=Zinc finger protein 865;+++[A0A0D9SG26_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 865 {ECO:0000313|Ensembl:ENSP00000487098};"]
[100507421,"'TMEM178B'",160,166,165,163.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","transmembrane protein 178B","[T178B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 178B; Flags: Precursor;+++[A0A087X1B3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 178B {ECO:0000313|Ensembl:ENSP00000484025};"]
[100507436,"'MICA'",1697,1453,1477,1542.33333333333,"05167///Kaposi's sarcoma-associated herpesvirus infection","H00288///Familial Mediterranean fever (FMF)",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0030881///beta-2-microglobulin binding","GO:0050776///regulation of immune response+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0051607///defense response to virus+++GO:0009408///response to heat+++GO:0046629///gamma-delta T cell activation+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0030101///natural killer cell activation+++GO:0019835///cytolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0032815///negative regulation of natural killer cell activation+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042742///defense response to bacterium+++GO:0016032///viral process+++GO:0002418///immune response to tumor cell+++GO:0001913///T cell mediated cytotoxicity","MHC class I polypeptide-related sequence A",{"$cut":{"chars":22248,"head":"[MICA_HUMAN|Reviewed]RecName: Full=MHC class I polypeptide-related sequence A; Short=MIC-A; Flags: Precursor;+++[A0A023SER7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74089.1}; Flags: Fragment;+++[A0A023SGA8_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74088.1}; Flags: Fragment;+++[A0A024RCL3_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A, isoform CRA_a {ECO:0000313|EMBL:EAX03394.1};+++[A0A0F6UUZ2_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I chain-related protein A {ECO:0000313|EMBL:AKE78870.1}; Flags: Fragment;+++[A0A0G2JJ55_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000405177};+++[A0A0G2JK11_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000412992};+++[A0A0K1NWU9_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75046.1}; Flags: Fragment;+++[A0A0K1NXC7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75047.1}; Flags: Fragment;+++[A0A0K1NXW1_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75045.1}; Flags: Fragment;+++[A0A0M3LAT3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11906.1}; Flags: Fragment;+++[A0A0M3LAU3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11916.1}; Flags: Fragment;+++[A0A0M3LAV0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11908.1}; Flags: Fragment;+++[A0A0M3LAV5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11926.1}; Flags: Fragment;+++[A0A0M3LAW0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11918.1}; Flags: Fragment;+++[A0A0M3LAW3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11936.1}; Flags: Fragment;+++[A0A0M3LAW8_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11928.1}; Flags: Fragment;+++[A0A0M3LAX6_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11938.1}; Flags: Fragment;+++[A0A0M3LAX7_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11946.1}; Flags: Fragment;+++[A0A0M3LAY5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11948.1}; Flags: Fragment;+++[A0A0M3LB05_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11905.1}; Flags: Fragment;+++[A0A0M3LB16_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11903.1}; Flags: Fragment;+++[A0A0M3LB17_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11915.1}; Flags: Fragment;+++[A0A0M3LB24_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11913.1}; Flags: Fragment;+++[A0A0M3LB25_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11925.1}; Flags: Fragment;+++[A0A0M3LB32_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11923.1}; Flags: Fragment;+++[A0A0M3LB33_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11935.1}; Flags: Fragment;+++[A0A0M3LB39_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11945.1}; Flags: Fragment;+++[A0A0M3LB40_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11933.1}; Flags: Fragment;+++[A0A0M3LB48_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11955.1}; Flags: Fragment;+++[A0A0M3LB49_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11943.1}; Flags: Fragment;+++[A0A0M3LB59_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11953.1}; Flags: Fragment;+++[A0A0M3LB64_HUMAN|Unreviewed]SubName: Ful"}}]
[100507462,"'GVQW2'",3,3,7,4.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","GVQW motif containing 2","[GVQW2_HUMAN|Reviewed]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};"]
[100507507,"'LOC100507507'",102,77,80,86.3333333333333,{"$nulls":7},"uncharacterized LOC100507507","[A0A2J8V2S2_PONAB|diamond]SubName: Full=T0078241 isoform 1 {ECO:0000313|EMBL:PNJ51828.1};"]
[100507588,"'TGFBR3L'",46,49,48,47.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transforming growth factor beta receptor 3 like","[TGR3L_HUMAN|Reviewed]RecName: Full=Transforming growth factor-beta receptor type 3-like protein; AltName: Full=TGF-beta receptor type-3-like protein; Short=TGFR-3L; AltName: Full=Transforming growth factor-beta receptor type III-like protein; Short=TGF-beta receptor type III-like protein;"]
[100507607,"'NPIPB9'",9.97,19.48,23.94,17.7966666666667,"01100///Metabolic pathways+++00650///Butanoate metabolism",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm",null,null,"nuclear pore complex interacting protein family member B9","[NPIB9_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B9;+++[F8VUA1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B9 {ECO:0000313|Ensembl:ENSP00000350444};"]
[100507650,"'RNF212B'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0000795///synaptonemal complex","GO:0046872///metal ion binding+++GO:0019789///SUMO transferase activity","GO:0007129///synapsis+++GO:0016925///protein sumoylation","ring finger protein 212B","[R212B_HUMAN|Reviewed]RecName: Full=RING finger protein 212B;+++[A8MVE6_HUMAN|Unreviewed]SubName: Full=RING finger protein 212B {ECO:0000313|Ensembl:ENSP00000382789};+++[G3V2N7_HUMAN|Unreviewed]SubName: Full=RING finger protein 212B {ECO:0000313|Ensembl:ENSP00000450766}; Flags: Fragment;+++[H0YJB3_HUMAN|Unreviewed]SubName: Full=RING finger protein 212B {ECO:0000313|Ensembl:ENSP00000451124}; Flags: Fragment;"]
[100507679,"'MUC22'",2,0,1,1,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"mucin 22","[MUC22_HUMAN|Reviewed]RecName: Full=Mucin-22; AltName: Full=Panbronchiolitis-related mucin-like protein 1; Flags: Precursor;+++[M1TIV1_HUMAN|Unreviewed]SubName: Full=Mucin 22 {ECO:0000313|EMBL:AGG40961.1};"]
[100507747,"'C13orf46'",47,76,56,59.6666666666667,{"$nulls":7},"chromosome 13 open reading frame 46","[CM046_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C13orf46 {ECO:0000305};"]
[100509620,"'LOC100509620'",1,2,1,1.33333333333333,"04923///Regulation of lipolysis in adipocytes+++03320///PPAR signaling pathway","H02106///Genetic obesity",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015267///channel activity","GO:0055085///transmembrane transport","putative aquaporin-7-like protein 3","[A0A075B734_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000456868};"]
[10051,"'SMC4'",188,202,190,193.333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005694///chromosome","GO:0003697///single-stranded DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0030261///chromosome condensation+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0051383///kinetochore organization+++GO:0045132///meiotic chromosome segregation+++GO:0000070///mitotic sister chromatid segregation+++GO:0010032///meiotic chromosome condensation+++GO:0051276///chromosome organization+++GO:0051301///cell division","structural maintenance of chromosomes 4","[SMC4_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 4; Short=SMC protein 4; Short=SMC-4; AltName: Full=Chromosome-associated polypeptide C; Short=hCAP-C; AltName: Full=XCAP-C homolog;+++[B3KXX5_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[C9IYK2_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418820}; Flags: Fragment;+++[C9J578_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417999}; Flags: Fragment;+++[C9J9E4_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417612}; Flags: Fragment;+++[C9JJ64_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420817}; Flags: Fragment;+++[C9JR83_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420121}; Flags: Fragment;+++[C9JVD8_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419360}; Flags: Fragment;+++[C9JWF0_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419247}; Flags: Fragment;+++[E9PD53_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[F8WCB7_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418434};+++[Q58F29_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH01557.1}; Flags: Fragment;+++[Q6NSG3_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH70161.1}; Flags: Fragment;+++[Q6P169_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH65259.1}; Flags: Fragment;"]
[10052,"'GJC1'",229,259,185,224.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0014704///intercalated disc+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016021///integral component of membrane+++GO:0005922///connexin complex","GO:0086077///gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling+++GO:0005216///ion channel activity+++GO:0086020///gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling","GO:0086014///atrial cardiac muscle cell action potential+++GO:0086021///SA node cell to atrial cardiac muscle cell communication by electrical coupling+++GO:0048738///cardiac muscle tissue development+++GO:0048468///cell development+++GO:0007043///cell-cell junction assembly+++GO:0086053///AV node cell to bundle of His cell communication by electrical coupling+++GO:0006936///muscle contraction+++GO:0007268///chemical synaptic transmission+++GO:0016264///gap junction assembly+++GO:0007601///visual perception+++GO:0001570///vasculogenesis","gap junction protein gamma 1","[CXG1_HUMAN|Reviewed]RecName: Full=Gap junction gamma-1 protein; AltName: Full=Connexin-45; Short=Cx45; AltName: Full=Gap junction alpha-7 protein;"]
[100526664,"'LY75-CD302'",3.41,0,1.72,1.71,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0043130///ubiquitin binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0038023///signaling receptor activity+++GO:0008270///zinc ion binding","GO:0006955///immune response+++GO:0008284///positive regulation of cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:0006954///inflammatory response+++GO:0051865///protein autoubiquitination+++GO:0006897///endocytosis+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0050821///protein stabilization+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0002643///regulation of tolerance induction+++GO:1905524///negative regulation of protein autoubiquitination","LY75-CD302 readthrough","[LY75_HUMAN|Reviewed]RecName: Full=Lymphocyte antigen 75; Short=Ly-75; AltName: Full=C-type lectin domain family 13 member B; AltName: Full=DEC-205; AltName: Full=gp200-MR6; AltName: CD_antigen=CD205; Flags: Precursor;"]
[100526693,"'ARPC4-TTLL3'",318.03,449.98,359.45,375.82,{"$nulls":4},"GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton","GO:0003779///actin binding+++GO:0070735///protein-glycine ligase activity","GO:0018094///protein polyglycylation+++GO:0006464///cellular protein modification process+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030041///actin filament polymerization+++GO:0030833///regulation of actin filament polymerization","ARPC4-TTLL3 readthrough","[A0A0A6YYG9_HUMAN|Unreviewed]SubName: Full=Protein ARPC4-TTLL3 {ECO:0000313|Ensembl:ENSP00000380427};+++[F8WCF6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000256|PIRNR:PIRNR039100};+++[F8WE39_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000402163};+++[H7C0A3_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000393764}; Flags: Fragment;"]
[100526694,"'MSANTD3-TMEFF1'",131.26,119.58,108.4,119.746666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding","GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007517///muscle organ development","MSANTD3-TMEFF1 readthrough","[TEFF1_HUMAN|Reviewed]RecName: Full=Tomoregulin-1; Short=TR-1; AltName: Full=H7365; AltName: Full=Transmembrane protein with EGF-like and one follistatin-like domain; Flags: Precursor;+++[A0A0A6YYJ0_HUMAN|Unreviewed]SubName: Full=Protein MSANTD3-TMEFF1 {ECO:0000313|Ensembl:ENSP00000424768};"]
[100526737,"'RBM14-RBM4'",6.22,2.61,0,2.94333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0098534///centriole assembly+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0002190///cap-independent translational initiation+++GO:0008380///RNA splicing+++GO:0045087///innate immune response+++GO:0030154///cell differentiation+++GO:0032055///negative regulation of translation in response to stress+++GO:0017148///negative regulation of translation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002192///IRES-dependent translational initiation of linear mRNA+++GO:0045947///negative regulation of translational initiation+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0046685///response to arsenic-containing substance+++GO:0097167///circadian regulation of translation+++GO:0006397///mRNA processing+++GO:0035278///miRNA mediated inhibition of translation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0046822///regulation of nucleocytoplasmic transport","RBM14-RBM4 readthrough","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0A0MSL8_HUMAN|Unreviewed]SubName: Full=RBM14-RBM4 readthrough {ECO:0000313|Ensembl:ENSP00000395880};+++[A0A0A6YYI9_HUMAN|Unreviewed]SubName: Full=Protein RBM14-RBM4 {ECO:0000313|Ensembl:ENSP00000421279};"]
[100526739,"'CENPS-CORT'",67.55,75.1,72.85,71.8333333333333,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0071821///FANCM-MHF complex+++GO:0005576///extracellular region","GO:0046982///protein heterodimerization activity+++GO:0005179///hormone activity","GO:0010469///regulation of signaling receptor activity","CENPS-CORT readthrough","[CENPS_HUMAN|Reviewed]RecName: Full=Centromere protein S; Short=CENP-S; AltName: Full=Apoptosis-inducing TAF9-like domain-containing protein 1; AltName: Full=FANCM-associated histone fold protein 1 {ECO:0000303|PubMed:20347428}; AltName: Full=FANCM-interacting histone fold protein 1 {ECO:0000303|PubMed:20347429}; AltName: Full=Fanconi anemia-associated polypeptide of 16 kDa;+++[A0A087WT10_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000473401};+++[A0A0U1RQL5_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000489060}; SubName: Full=Centromere protein S {ECO:0000313|Ensembl:ENSP00000489524};"]
[100526760,"'ABHD14A-ACY1'",0,22.9,0,7.63333333333333,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01230///Biosynthesis of amino acids+++00220///Arginine biosynthesis+++01210///2-Oxocarboxylic acid metabolism+++01130///Biosynthesis of antibiotics","H01146///Aminoacylase 1 deficiency","M00028///Ornithine biosynthesis, glutamate => ornithine","R00669///N2-Acetyl-L-ornithine amidohydrolase   N-Acetylornithine + H2O <=> Acetate + L-Ornithine+++R10553///N-acetyl-L-cysteine-S-conjugate amidohydrolase (carboxylate-forming)   S-Substituted N-acetyl-L-cysteine + H2O <=> S-Substituted L-cysteine + Acetate","GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0004046///aminoacylase activity+++GO:0008237///metallopeptidase activity","GO:0006520///cellular amino acid metabolic process+++GO:0006508///proteolysis","ABHD14A-ACY1 readthrough","[A0A1B0GU64_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000489981};+++[A0A1B0GUT4_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490236};+++[A0A1B0GV31_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490353}; Flags: Fragment;+++[A0A1B0GVA5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490434}; Flags: Fragment;+++[A0A1B0GVC5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490460}; Flags: Fragment;+++[A0A1B0GVN8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490593}; Flags: Fragment;+++[A0A1B0GVQ8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490616}; Flags: Fragment;+++[A0A1B0GVW5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490680}; Flags: Fragment;+++[A0A1B0GW23_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490744}; Flags: Fragment;+++[A0A1B0GW28_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490750}; Flags: Fragment;+++[A0A1B0GWD9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490887};+++[B4DNW0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60317, highly similar to Aminoacylase-1 {ECO:0000313|EMBL:BAG60372.1};+++[C9JMV9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420487};+++[F2Z3Q0_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420395};"]
[100526761,"'CCDC169-SOHLH2'",8.5,0,0,2.83333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity","GO:0007283///spermatogenesis+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0009994///oocyte differentiation","CCDC169-SOHLH2 readthrough","[SOLH2_HUMAN|Reviewed]RecName: Full=Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2;"]
[100526767,"'RNF103-CHMP3'",9.24,0,0,3.08,"04217///Necroptosis+++04144///Endocytosis",null,"M00412///ESCRT-III complex",null,"GO:0031410///cytoplasmic vesicle+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0000815///ESCRT III complex+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016021///integral component of membrane+++GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005770///late endosome+++GO:0010494///cytoplasmic stress granule+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0031902///late endosome membrane","GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0031210///phosphatidylcholine binding+++GO:0050681///androgen receptor binding+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0003727///single-stranded RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:1990381///ubiquitin-specific protease binding+++GO:0003697///single-stranded DNA binding+++GO:0051213///dioxygenase activity+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0031490///chromatin DNA binding+++GO:0032452///histone demethylase activity","GO:0007034///vacuolar transport","RNF103-CHMP3 readthrough","[CHMP3_HUMAN|Reviewed]RecName: Full=Charged multivesicular body protein 3; AltName: Full=Chromatin-modifying protein 3; AltName: Full=Neuroendocrine differentiation factor; AltName: Full=Vacuolar protein sorting-associated protein 24; Short=hVps24;+++[A0A140T963_HUMAN|Unreviewed]SubName: Full=RNF103-CHMP3 readthrough {ECO:0000313|Ensembl:ENSP00000392995}; Flags: Fragment;"]
[100526772,"'TMEM110-MUSTN1'",0.32,45.09,0,15.1366666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005246///calcium channel regulator activity","GO:0042246///tissue regeneration+++GO:0035988///chondrocyte proliferation+++GO:0002062///chondrocyte differentiation","TMEM110-MUSTN1 readthrough","[A8MSY1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422941};+++[H0Y8V1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422189}; Flags: Fragment;"]
[100526783,"'C15orf38-AP3S2'",596.85,614.89,593.37,601.703333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030117///membrane coat+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051126///negative regulation of actin nucleation","C15orf38-AP3S2 readthrough","[A0A0A6YYH1_HUMAN|Unreviewed]SubName: Full=Protein C15orf38-AP3S2 {ECO:0000313|Ensembl:ENSP00000381377};+++[H0YL85_HUMAN|Unreviewed]SubName: Full=C15orf38-AP3S2 readthrough {ECO:0000313|Ensembl:ENSP00000453100}; Flags: Fragment;+++[H0YMK0_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588}; Flags: Fragment;"]
[100526832,"'PHOSPHO2-KLHL23'",0,3.96,0,1.32,"01100///Metabolic pathways+++00750///Vitamin B6 metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal",null,null,"R02494///pyridoxamine-5'-phosphate phosphohydrolase Pyridoxamine + Orthophosphate <=> Pyridoxamine phosphate + H2O+++R01911///pyridoxine-5'-phosphate phosphohydrolase Pyridoxine + Orthophosphate <=> Pyridoxine phosphate + H2O+++R00173///pyridoxal-5'-phosphate phosphohydrolase Pyridoxal phosphate + H2O <=> Pyridoxal + Orthophosphate","GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity+++GO:0033883///pyridoxal phosphatase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding","GO:0016567///protein ubiquitination","PHOSPHO2-KLHL23 readthrough","[KLH23_HUMAN|Reviewed]RecName: Full=Kelch-like protein 23;"]
[100526835,"'FPGT-TNNI3K'",13.34,25.48,15.73,18.1833333333333,"00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H02125///Cardiac conduction disease with dilated cardiomyopathy",null,"R01951///GTP:beta-L-fucose-1-phosphate guanylyltransferase GTP + L-Fucose 1-phosphate <=> Diphosphate + GDP-L-fucose","GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade","FPGT-TNNI3K readthrough","[TNI3K_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase TNNI3K; EC=2.7.11.1; AltName: Full=Cardiac ankyrin repeat kinase; AltName: Full=Cardiac troponin I-interacting kinase; AltName: Full=TNNI3-interacting kinase;+++[A6NHC7_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000359930};+++[E9PKE1_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000433587}; Flags: Fragment;+++[V9GXZ4_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000450895};"]
[100526842,"'RPL17-C18orf32'",62.25,91.27,76.06,76.5266666666667,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0002181///cytoplasmic translation","RPL17-C18orf32 readthrough","[A0A0A0MRF8_HUMAN|Unreviewed]SubName: Full=RPL17-C18orf32 readthrough {ECO:0000313|Ensembl:ENSP00000352143};+++[A0A0A6YYL6_HUMAN|Unreviewed]SubName: Full=Protein RPL17-C18orf32 {ECO:0000313|Ensembl:ENSP00000463379};"]
[100527943,"'TGIF2-RAB5IF'",8.53,0,0,2.84333333333333,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","TGIF2-RAB5IF readthrough","[A0A0A6YYL0_HUMAN|Unreviewed]SubName: Full=Protein TGIF2-C20orf24 {ECO:0000313|Ensembl:ENSP00000454021};"]
[100527963,"'PMF1-BGLAP'",88.59,117.1,77.54,94.41,"04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0000818///nuclear MIS12/MIND complex+++GO:0005829///cytosol+++GO:0005667///transcription factor complex+++GO:0000444///MIS12/MIND type complex+++GO:0005794///Golgi apparatus+++GO:0005694///chromosome+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region","GO:0043522///leucine zipper domain binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding","GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006366///transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation","PMF1-BGLAP readthrough","[PMF1_HUMAN|Reviewed]RecName: Full=Polyamine-modulated factor 1; Short=PMF-1;+++[A0A087WT04_HUMAN|Unreviewed]SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000458021};+++[U3KQ54_HUMAN|Unreviewed]SubName: Full=HCG2044777 {ECO:0000313|EMBL:EAW52985.1}; SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000475561};+++[V9GYH6_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476760}; Flags: Fragment;+++[V9GYI0_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476770};"]
[100527978,"'TMEM56-RWDD3'",3.14,12.94,9.55,8.54333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0033235///positive regulation of protein sumoylation+++GO:1902073///positive regulation of hypoxia-inducible factor-1alpha signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","TMEM56-RWDD3 readthrough","[S4R3V7_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000474793}; Flags: Fragment;+++[S4R434_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000475025};"]
[100528020,"'FAM187A'",9,17,22,16,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"family with sequence similarity 187 member A","[F187A_HUMAN|Reviewed]RecName: Full=Ig-like V-type domain-containing protein FAM187A; Flags: Precursor;"]
[100528030,"'POC1B-GALNT4'",18.2,5.63,13.69,12.5066666666667,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0006486///protein glycosylation","POC1B-GALNT4 readthrough","[GALT4_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 4; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 4; Short=GalNAc-T4; Short=pp-GaNTase 4; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 4; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4;+++[F8VUJ3_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[F8VZB3_HUMAN|Unreviewed]SubName: Full=POC1B-GALNT4 readthrough {ECO:0000313|Ensembl:ENSP00000447754};"]
[100528062,"'ARMCX5-GPRASP2'",53.15,58.69,114.34,75.3933333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0003697///single-stranded DNA binding+++GO:0001540///amyloid-beta binding+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity","GO:0050769///positive regulation of neurogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:1990172///G protein-coupled receptor catabolic process+++GO:0007611///learning or memory+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0006351///transcription, DNA-templated+++GO:0032197///transposition, RNA-mediated+++GO:0008333///endosome to lysosome transport+++GO:0051965///positive regulation of synapse assembly","ARMCX5-GPRASP2 readthrough","[GASP2_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 2; Short=GASP-2;"]
[100528064,"'NEDD8-MDP1'",0,3.22,2.71,1.97666666666667,"04144///Endocytosis+++04217///Necroptosis","H01202///Cataract","M00412///ESCRT-III complex",null,"GO:0030659///cytoplasmic vesicle membrane+++GO:0031902///late endosome membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0000815///ESCRT III complex+++GO:0030496///midbody+++GO:0030117///membrane coat+++GO:0005737///cytoplasm","GO:0016791///phosphatase activity","GO:0016311///dephosphorylation","NEDD8-MDP1 readthrough","[E9PL57_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000431482}; Flags: Fragment;+++[E9PS38_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000432117};+++[S4R3E9_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000474249};"]
[100529063,"'BCL2L2-PABPN1'",34.93,67.68,0,34.2033333333333,"03015///mRNA surveillance pathway+++05164///Influenza A","H00704///Oculopharyngeal muscular dystrophy (OPMD)",null,null,"GO:0005774///vacuolar membrane+++GO:0042405///nuclear inclusion body+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0031301///integral component of organelle membrane+++GO:0016607///nuclear speck+++GO:0005887///integral component of plasma membrane+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex","GO:0097718///disordered domain specific binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0070063///RNA polymerase binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043621///protein self-association+++GO:0051400///BH domain binding+++GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity","GO:0031124///mRNA 3'-end processing+++GO:0015891///siderophore transport+++GO:0060011///Sertoli cell proliferation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0006396///RNA processing+++GO:1904247///positive regulation of polynucleotide adenylyltransferase activity+++GO:0007283///spermatogenesis+++GO:0055072///iron ion homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006936///muscle contraction+++GO:0006397///mRNA processing+++GO:0006369///termination of RNA polymerase II transcription+++GO:0000165///MAPK cascade+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0046778///modification by virus of host mRNA processing+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage","BCL2L2-PABPN1 readthrough","[AR1_XENLA|diamond]RecName: Full=Apoptosis regulator R1; AltName: Full=XR1; Flags: Fragment;+++[B2CL2_BOVIN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_CANLF|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_HUMAN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_MOUSE|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W; AltName: Full=c98;+++[PAB2A_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-A; Short=PABP-2-A; Short=Poly(A)-binding protein 2-A; AltName: Full=Nuclear poly(A)-binding protein 1-A; AltName: Full=Poly(A)-binding protein II-A; Short=PABII-A; AltName: Full=Polyadenylate-binding nuclear protein 1-A; AltName: Full=XLnPABP2-A; AltName: Full=nPABP2-A; AltName: Full=xPABPII-A;+++[PAB2B_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-B; Short=PABP-2-B; Short=Poly(A)-binding protein 2-B; AltName: Full=Nuclear poly(A)-binding protein 1-B; AltName: Full=Poly(A)-binding protein II-B; Short=PABII-B; AltName: Full=Polyadenylate-binding nuclear protein 1-B; AltName: Full=XLnPABP2-B; AltName: Full=nPABP2-B; AltName: Full=xPABPII-B;+++[PABP2_BOVIN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_HUMAN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_MOUSE|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_XENTR|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[S22AH_BOVIN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Lipocalin-2 receptor;+++[S22AH_HUMAN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor; AltName: Full=Neutrophil gelatinase-associated lipocalin receptor; Short=NgalR;+++[S22AH_MOUSE|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AH_RAT|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AV_HUMAN|diamond]RecName: Full=Putative solute carrier family 22 member 31 {ECO:0000305};"]
[100529097,"'RPL36A-HNRNPH2'",1022.41,788.78,852.65,887.946666666667,"03010///Ribosome","H00658///Syndromic X-linked mental retardation+++H00125///Fabry disease","M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes","R01329///Epimelibiose galactohydrolase Epimelibiose + H2O <=> D-Mannose + D-Galactose+++R03634///Stachyose + H2O <=> Raffinose + D-Galactose+++R05961///H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide+++R01194///3-O-alpha-D-Galactosyl-1D-myo-inositol galactohydrolase; 1-alpha-D-Galactosyl-myo-inositol alpha-D-Galactosyl-(1->3)-1D-myo-inositol + H2O <=> myo-Inositol + D-Galactose+++R04019///Digalactosylceramide galactohydrolase Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose+++R04470///Digalactosyl-diacylglycerol galactohydrolase Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose+++R05549///D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose+++R06091///Melibiose + H2O <=> D-Galactose + D-Glucose+++R01104///Galactosylglycerol galactohydrolase 3-beta-D-Galactosyl-sn-glycerol + H2O <=> D-Galactose + Glycerol+++R01101///melibiose galactohydrolase Melibiose + H2O <=> D-Galactose + D-Glucose+++R02926///Melibiitol galactohydrolase Melibiitol + H2O <=> D-Sorbitol + D-Galactose+++R01103///Raffinose galactohydrolase Raffinose + H2O <=> D-Galactose + Sucrose","GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005783///endoplasmic reticulum","GO:0003735///structural constituent of ribosome","GO:0006412///translation","RPL36A-HNRNPH2 readthrough","[H0Y3V9_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386974};+++[H7BZ11_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386655};"]
[100529144,"'CORO7-PAM16'",0,0,27.96,9.32,null,"H01830///Spondylometaphyseal dysplasia, Megarbane-Dagher-Melki type (SMDMDM)",null,null,"GO:0005794///Golgi apparatus","GO:0003779///actin binding","GO:0001503///ossification+++GO:0030150///protein import into mitochondrial matrix+++GO:0032780///negative regulation of ATPase activity+++GO:0030041///actin filament polymerization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","CORO7-PAM16 readthrough","[A0A0A6YYL4_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};+++[I3L167_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};"]
[100529215,"'ZNF559-ZNF177'",6.33,0,6.27,4.2,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","ZNF559-ZNF177 readthrough","[ZN177_HUMAN|Reviewed]RecName: Full=Zinc finger protein 177;+++[S4R342_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473911};+++[S4R365_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473968};+++[S4R367_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473974}; Flags: Fragment;+++[S4R3A1_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474076};+++[S4R3B1_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474108}; Flags: Fragment;+++[S4R3H7_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474354};+++[S4R3Q2_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474602}; Flags: Fragment;+++[S4R3T9_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474716}; Flags: Fragment;+++[S4R401_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474918}; Flags: Fragment;+++[S4R422_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474980};"]
[100529239,"'RPS10-NUDT3'",3.32,0,10.35,4.55666666666667,"03010///Ribosome","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0022627///cytosolic small ribosomal subunit+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0003735///structural constituent of ribosome","GO:0000028///ribosomal small subunit assembly","RPS10-NUDT3 readthrough","[A0A1W2PQS6_HUMAN|Unreviewed]SubName: Full=RPS10-NUDT3 readthrough {ECO:0000313|Ensembl:ENSP00000491891};+++[A0A2R8Y6L3_HUMAN|Unreviewed]SubName: Full=RPS10-NUDT3 readthrough {ECO:0000313|Ensembl:ENSP00000495405}; Flags: Fragment;+++[S4R435_HUMAN|Unreviewed]SubName: Full=RPS10-NUDT3 readthrough {ECO:0000313|Ensembl:ENSP00000475027}; Flags: Fragment;"]
[100529240,"'ZNF816-ZNF321P'",22.7,15.39,21.51,19.8666666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","ZNF816-ZNF321P readthrough","[ZN321_HUMAN|Reviewed]RecName: Full=Putative protein ZNF321; AltName: Full=Zinc finger protein 321 pseudogene;+++[A0A0X1KG74_HUMAN|Unreviewed]SubName: Full=ZNF816-ZNF321P readthrough {ECO:0000313|Ensembl:ENSP00000375656};"]
[100529251,"'CKLF-CMTM1'",0,1.13,1.39,0.84,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005125///cytokine activity","GO:0006935///chemotaxis","CKLF-CMTM1 readthrough","[A0A087WVB3_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000479319};+++[A0A087X286_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000484781};+++[E9PIV8_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433857};+++[E9PLU7_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000435007}; SubName: Full=Chemokine-like factor {ECO:0000313|Ensembl:ENSP00000431270};+++[E9PSG2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433998};+++[H0YDF2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433503}; Flags: Fragment;"]
[100529257,"'SYNJ2BP-COX16'",4.49,0,0,1.49666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016323///basolateral plasma membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0031966///mitochondrial membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0098839///postsynaptic density membrane+++GO:0031594///neuromuscular junction","GO:0035255///ionotropic glutamate receptor binding","GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0043113///receptor clustering+++GO:0098609///cell-cell adhesion+++GO:0097120///receptor localization to synapse+++GO:0007268///chemical synaptic transmission","SYNJ2BP-COX16 readthrough","[A0A087WTA2_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000477705};+++[A0A087WUM0_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000478757}; Flags: Fragment;+++[A0A087WX56_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000480746}; Flags: Fragment;+++[A0A087WYV9_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000482133};+++[A0A087X1F5_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000484161}; Flags: Fragment;"]
[100529261,"'CHURC1-FNTB'",70.03,23.82,0,31.2833333333333,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis",null,null,"R09844///farnesyl-diphosphate:protein-cysteine farnesyltransferase trans,trans-Farnesyl diphosphate + Protein-cysteine <=> S-Farnesyl protein + Diphosphate","GO:0005965///protein farnesyltransferase complex","GO:0004659///prenyltransferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004660///protein farnesyltransferase activity+++GO:0003824///catalytic activity+++GO:0008270///zinc ion binding","GO:0007275///multicellular organism development+++GO:0018343///protein farnesylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0018342///protein prenylation","CHURC1-FNTB readthrough","[FNTB_HUMAN|Reviewed]RecName: Full=Protein farnesyltransferase subunit beta; Short=FTase-beta; EC=2.5.1.58; AltName: Full=CAAX farnesyltransferase subunit beta; AltName: Full=Ras proteins prenyltransferase subunit beta;+++[B4DL54_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000447121}; SubName: Full=cDNA FLJ59570, highly similar to Protein farnesyltransferase subunit beta {ECO:0000313|EMBL:BAG59416.1};+++[H0YIM3_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000449668}; Flags: Fragment;+++[H0YIM9_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000449709}; Flags: Fragment;+++[H0YJ25_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000450692}; Flags: Fragment;"]
[10053,"'AP1M2'",22,10,12,14.6666666666667,"04142///Lysosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000139///Golgi membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0030131///clathrin adaptor complex+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006605///protein targeting+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0050690///regulation of defense response to virus by virus+++GO:0006886///intracellular protein transport+++GO:0006903///vesicle targeting+++GO:0015031///protein transport","adaptor related protein complex 1 subunit mu 2","[AP1M2_HUMAN|Reviewed]RecName: Full=AP-1 complex subunit mu-2; AltName: Full=AP-mu chain family member mu1B; AltName: Full=Adaptor protein complex AP-1 subunit mu-2; AltName: Full=Adaptor-related protein complex 1 subunit mu-2; AltName: Full=Clathrin assembly protein complex 1 mu-2 medium chain 2; AltName: Full=Golgi adaptor HA1/AP1 adaptin mu-2 subunit; AltName: Full=Mu-adaptin 2; AltName: Full=Mu1B-adaptin;+++[K7EJJ1_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465193}; Flags: Fragment;+++[K7EK69_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465488}; Flags: Fragment;+++[K7EL08_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465865}; Flags: Fragment;+++[K7EMG5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000466494}; Flags: Fragment;+++[K7EPI9_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467406};+++[K7EPR4_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467498}; Flags: Fragment;+++[K7ERH5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000468260}; Flags: Fragment;+++[Q53GI5_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 1, mu 2 subunit variant {ECO:0000313|EMBL:BAD96666.1}; Flags: Fragment;"]
[100532726,"'NDUFC2-KCTD14'",174.33,232.79,233.48,213.533333333333,"00190///Oxidative phosphorylation+++01100///Metabolic pathways+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04714///Thermogenesis+++05010///Alzheimer's disease+++05016///Huntington's disease+++04723///Retrograde endocannabinoid signaling","H00810///Progressive myoclonic epilepsy (PME/ EPM)","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0070469///respiratory chain+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0055114///oxidation-reduction process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone","NDUFC2-KCTD14 readthrough","[NDUCR_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2; AltName: Full=NDUFC2-KCTD14 readthrough transcript protein;+++[A0A087WUM3_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000478766};+++[A0A087WY27_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000481472};+++[E9PRQ4_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000435967};"]
[100532731,"'COMMD3-BMI1'",229.52,154.84,90.34,158.233333333333,"05206///MicroRNAs in cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer","H00025///Penile cancer",null,null,"GO:0016604///nuclear body+++GO:0035102///PRC1 complex+++GO:0005829///cytosol","GO:1990841///promoter-specific chromatin binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0006342///chromatin silencing+++GO:0006814///sodium ion transport","COMMD3-BMI1 readthrough","[BMI1_HUMAN|Reviewed]RecName: Full=Polycomb complex protein BMI-1; AltName: Full=Polycomb group RING finger protein 4; AltName: Full=RING finger protein 51;+++[Q5T8Z1_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000398759}; Flags: Fragment;+++[R4GMW6_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473382}; Flags: Fragment;+++[R4GMX3_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473391};+++[R4GN54_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473495}; Flags: Fragment;"]
[100532736,"'MINOS1-NBL1'",0,0,7.9,2.63333333333333,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005743///mitochondrial inner membrane+++GO:0061617///MICOS complex+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0036122///BMP binding+++GO:0016015///morphogen activity+++GO:0042803///protein homodimerization activity","GO:0030514///negative regulation of BMP signaling pathway+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0038098///sequestering of BMP from receptor via BMP binding+++GO:0048263///determination of dorsal identity+++GO:0048812///neuron projection morphogenesis+++GO:0045666///positive regulation of neuron differentiation+++GO:0007399///nervous system development","MINOS1-NBL1 readthrough","[NBL1_HUMAN|Reviewed]RecName: Full=Neuroblastoma suppressor of tumorigenicity 1; AltName: Full=DAN domain family member 1; AltName: Full=Protein N03; AltName: Full=Zinc finger protein DAN; Flags: Precursor;+++[R4GMM1_HUMAN|Unreviewed]SubName: Full=MINOS1-NBL1 readthrough {ECO:0000313|Ensembl:ENSP00000473256}; Flags: Fragment;+++[R4GMY4_HUMAN|Unreviewed]RecName: Full=MICOS complex subunit MIC10 {ECO:0000256|RuleBase:RU363011};+++[R4GNA1_HUMAN|Unreviewed]RecName: Full=MICOS complex subunit MIC10 {ECO:0000256|RuleBase:RU363011}; Flags: Fragment;"]
[100533105,"'C8orf44-SGK3'",53.49,70.37,0,41.2866666666667,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0055037///recycling endosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0005737///cytoplasm+++GO:0005795///Golgi stack+++GO:0005654///nucleoplasm+++GO:0005769///early endosome","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0035091///phosphatidylinositol binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0016567///protein ubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0016320///endoplasmic reticulum membrane fusion+++GO:0090168///Golgi reassembly","C8orf44-SGK3 readthrough","[SGK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk3; EC=2.7.11.1; AltName: Full=Cytokine-independent survival kinase; AltName: Full=Serum/glucocorticoid-regulated kinase 3; AltName: Full=Serum/glucocorticoid-regulated kinase-like;+++[A0A024R807_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};"]
[100533106,"'ZHX1-C8orf76'",3.76,0,5.89,3.21666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","ZHX1-C8orf76 readthrough","[ZHX1R_HUMAN|Reviewed]RecName: Full=Zinc fingers and homeoboxes protein 1, isoform 2; AltName: Full=ZHX1-C8orf76 readthrough transcript protein;+++[A0A0X1KG80_HUMAN|Unreviewed]SubName: Full=Zinc fingers and homeoboxes protein 1, isoform 2 {ECO:0000313|Ensembl:ENSP00000481928}; Flags: Fragment;"]
[100533178,"'PRORY'",0,0,1,0.333333333333333,{"$nulls":7},"proline rich Y-linked","[PRORY_HUMAN|Reviewed]RecName: Full=Proline-rich protein, Y-linked;"]
[100533183,"'ZNF664-RFLNA'",11.39,101.51,50.8,54.5666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061181///regulation of chondrocyte development+++GO:0061572///actin filament bundle organization","ZNF664-RFLNA readthrough","[RFLA_HUMAN|Reviewed]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;"]
[100533467,"'BIVM-ERCC5'",692.22,605.64,592.05,629.97,"03420///Nucleotide excision repair","H00403///Disorders of nucleotide excision repair+++H01428///Xeroderma pigmentosum (XP)",null,null,"GO:0005634///nucleus","GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds","GO:0006281///DNA repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006295///nucleotide-excision repair, DNA incision, 3'-to lesion+++GO:0006289///nucleotide-excision repair","BIVM-ERCC5 readthrough","[A0A1W2PRR4_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492455}; Flags: Fragment;+++[A0A1W2PRU8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492444}; Flags: Fragment;+++[A0A1W2PS85_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492684};+++[Q59FZ7_HUMAN|Unreviewed]SubName: Full=DNA-repair protein complementing XP-G cells variant {ECO:0000313|EMBL:BAD92549.1}; Flags: Fragment;+++[R4GMW8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000491742}; SubName: Full=DNA repair protein-complementing XP-G cells {ECO:0000313|Ensembl:ENSP00000473384}; SubName: Full=ERCC5-202 protein {ECO:0000313|EMBL:CDY80175.1};"]
[100533496,"'TVP23C-CDRT4'",80.76,118.08,86.98,95.2733333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009306///protein secretion+++GO:0016192///vesicle-mediated transport","TVP23C-CDRT4 readthrough","[TV23C_HUMAN|Reviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog C;+++[A0A0A6YYB9_HUMAN|Unreviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};+++[E5RGC5_HUMAN|Unreviewed]SubName: Full=Golgi apparatus membrane protein TVP23 homolog C {ECO:0000313|Ensembl:ENSP00000428748}; SubName: Full=TVP23C-CDRT4 readthrough {ECO:0000313|Ensembl:ENSP00000430143};"]
[100533952,"'RBAK-RBAKDN'",0,0,1.13,0.376666666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","RBAK-RBAKDN readthrough","[A0A0A6YYG8_HUMAN|Unreviewed]SubName: Full=Protein RBAK-RBAKDN {ECO:0000313|Ensembl:ENSP00000380112};+++[I3L0D1_HUMAN|Unreviewed]SubName: Full=HCG1647537, isoform CRA_b {ECO:0000313|EMBL:EAW87320.1}; SubName: Full=RBAK-RBAKDN readthrough {ECO:0000313|Ensembl:ENSP00000385560};"]
[100534012,"'TNFAIP8L2-SCNM1'",0,7.86,0,2.62,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0019899///enzyme binding+++GO:0046872///metal ion binding","GO:0042981///regulation of apoptotic process+++GO:0050868///negative regulation of T cell activation+++GO:0050728///negative regulation of inflammatory response+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045087///innate immune response","TNFAIP8L2-SCNM1 readthrough","[SCNM1_HUMAN|Reviewed]RecName: Full=Sodium channel modifier 1;"]
[100534592,"'URGCP-MRPS24'",0,0,3.84,1.28,{"$nulls":4},"GO:0005761///mitochondrial ribosome+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005743///mitochondrial inner membrane","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070125///mitochondrial translational elongation+++GO:0032543///mitochondrial translation+++GO:0070126///mitochondrial translational termination+++GO:0006412///translation","URGCP-MRPS24 readthrough","[S4R325_HUMAN|Unreviewed]SubName: Full=URGCP-MRPS24 readthrough {ECO:0000313|Ensembl:ENSP00000473871};"]
[100534599,"'ISY1-RAB43'",467.96,380.59,392.62,413.723333333333,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000974///Prp19 complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex+++GO:0032588///trans-Golgi network membrane+++GO:0071012///catalytic step 1 spliceosome+++GO:0071020///post-spliceosomal complex+++GO:0030670///phagocytic vesicle membrane+++GO:0045335///phagocytic vesicle+++GO:0070062///extracellular exosome","GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005525///GTP binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003924///GTPase activity+++GO:0046872///metal ion binding","GO:0000350///generation of catalytic spliceosome for second transesterification step","ISY1-RAB43 readthrough","[ISY1_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ISY1 homolog;+++[H9XFA1_HUMAN|Unreviewed]SubName: Full=ISY1-RAB43 {ECO:0000313|EMBL:AFG72967.1}; Flags: Fragment;"]
[10054,"'UBA2'",707,695,642,681.333333333333,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0031510///SUMO activating enzyme complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0005524///ATP binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0016881///acid-amino acid ligase activity+++GO:0000166///nucleotide binding+++GO:0008047///enzyme activator activity+++GO:0019948///SUMO activating enzyme activity+++GO:0000287///magnesium ion binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0044388///small protein activating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0044241///lipid digestion+++GO:0072148///epithelial cell fate commitment+++GO:0007411///axon guidance+++GO:0021800///cerebral cortex tangential migration+++GO:0030154///cell differentiation+++GO:0001764///neuron migration+++GO:0021846///cell proliferation in forebrain+++GO:0007275///multicellular organism development+++GO:0046622///positive regulation of organ growth+++GO:0043085///positive regulation of catalytic activity+++GO:0021772///olfactory bulb development+++GO:0030900///forebrain development+++GO:0010628///positive regulation of gene expression+++GO:0021759///globus pallidus development+++GO:0016925///protein sumoylation+++GO:0007399///nervous system development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0021831///embryonic olfactory bulb interneuron precursor migration+++GO:0006355///regulation of transcription, DNA-templated","ubiquitin like modifier activating enzyme 2","[SAE2_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 2; EC=2.3.2.-; AltName: Full=Anthracycline-associated resistance ARX; AltName: Full=Ubiquitin-like 1-activating enzyme E1B; AltName: Full=Ubiquitin-like modifier-activating enzyme 2;+++[K7EPL2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000467433}; Flags: Fragment;+++[K7ES38_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468538};+++[K7ESK7_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468756}; Flags: Fragment;+++[U3KQ55_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475565};+++[U3KQ93_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475656};"]
[10055,"'SAE1'",1124,1032,1047,1067.66666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0031510///SUMO activating enzyme complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019948///SUMO activating enzyme activity+++GO:0043008///ATP-dependent protein binding+++GO:0044388///small protein activating enzyme binding+++GO:0008047///enzyme activator activity+++GO:0016874///ligase activity+++GO:0046982///protein heterodimerization activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0008022///protein C-terminus binding+++GO:0004839///ubiquitin activating enzyme activity","GO:0006464///cellular protein modification process+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0043085///positive regulation of catalytic activity","SUMO1 activating enzyme subunit 1","[SAE1_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 1; AltName: Full=Ubiquitin-like 1-activating enzyme E1A; Contains: RecName: Full=SUMO-activating enzyme subunit 1, N-terminally processed;+++[A0A024R0R4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_b {ECO:0000313|EMBL:EAW57462.1};+++[B3KNJ4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW57460.1}; SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000398818}; SubName: Full=cDNA FLJ14689 fis, clone NT2RP2005204, highly similar to Ubiquitin-like 1-activating enzyme E1A {ECO:0000313|EMBL:BAG51356.1};+++[M0QX65_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000468931}; Flags: Fragment;+++[M0QYM8_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469938}; Flags: Fragment;+++[M0QYP2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469978}; Flags: Fragment;+++[M0QZS6_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000470741};+++[M0R054_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000471010}; Flags: Fragment;+++[M0R286_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000472389}; Flags: Fragment;+++[M0R375_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000473037};"]
[10056,"'FARSB'",449,383,400,410.666666666667,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0016020///membrane+++GO:0009328///phenylalanine-tRNA ligase complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding+++GO:0004826///phenylalanine-tRNA ligase activity","GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0006412///translation+++GO:0051290///protein heterotetramerization","phenylalanyl-tRNA synthetase subunit beta","[SYFB_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase beta subunit; EC=6.1.1.20 {ECO:0000269|PubMed:20223217}; AltName: Full=Phenylalanyl-tRNA synthetase beta subunit; Short=PheRS;+++[Q9BR63_HUMAN|Unreviewed]SubName: Full=FARSB protein {ECO:0000313|EMBL:AAH06502.2}; Flags: Fragment;"]
[10057,"'ABCC5'",3674,4307,4191,4057.33333333333,"01523///Antifolate resistance+++02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity","GO:0015711///organic anion transport+++GO:0055085///transmembrane transport+++GO:0030213///hyaluronan biosynthetic process+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport","ATP binding cassette subfamily C member 5","[MRP5_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 5; AltName: Full=ATP-binding cassette sub-family C member 5; AltName: Full=Multi-specific organic anion transporter C; Short=MOAT-C; AltName: Full=SMRP; AltName: Full=pABC11;+++[A5PKY6_HUMAN|Unreviewed]SubName: Full=ABCC5 protein {ECO:0000313|EMBL:AAI42671.1}; SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404809};+++[C9JZL5_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000399726}; Flags: Fragment;+++[E9PET4_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000390911};+++[F8WCY8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000403510};+++[F8WDH3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000409913};+++[H7C271_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404302}; Flags: Fragment;"]
[10058,"'ABCB6'",218,292,274,261.333333333333,"02010///ABC transporters","H00232///Hereditary stomatocytosis (HSt)+++H01027///Anophthalmia and microphthalmia (A/M)+++H02001///Familial pseudohyperkalemia",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005740///mitochondrial envelope+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005739///mitochondrion+++GO:0031307///integral component of mitochondrial outer membrane","GO:0015232///heme transporter activity+++GO:0020037///heme binding+++GO:0000166///nucleotide binding+++GO:0015562///efflux transmembrane transporter activity+++GO:0015439///heme-transporting ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0016887///ATPase activity","GO:0015886///heme transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007420///brain development+++GO:0055085///transmembrane transport+++GO:0043588///skin development+++GO:0006779///porphyrin-containing compound biosynthetic process","ATP binding cassette subfamily B member 6 (Langereis blood group)","[ABCB6_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family B member 6, mitochondrial; AltName: Full=Mitochondrial ABC transporter 3; Short=Mt-ABC transporter 3; AltName: Full=P-glycoprotein-related protein; AltName: Full=Ubiquitously-expressed mammalian ABC half transporter;+++[A0A024R436_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6, isoform CRA_f {ECO:0000313|EMBL:EAW70701.1};+++[A0A1D9ITY9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6 {ECO:0000313|EMBL:AOZ15555.1}; Flags: Fragment;+++[H7BXK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000295750}; Flags: Fragment;+++[H7C049_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000392988}; Flags: Fragment;+++[H7C1R6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000401811}; Flags: Fragment;+++[H7C245_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000404006}; Flags: Fragment;+++[H7C3Z0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000414646}; Flags: Fragment;+++[U3TD89_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91502.1}; Flags: Fragment;+++[U3TGG4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91501.2}; Flags: Fragment;+++[U3THN0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91500.2};+++[U3THP2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91503.1}; Flags: Fragment;+++[U3TJJ6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91499.1}; Flags: Fragment;+++[U3TJK0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91504.1}; Flags: Fragment;"]
[10059,"'DNM1L'",837.2,859,747.03,814.41,"04214///Apoptosis - fly+++04217///Necroptosis+++04668///TNF signaling pathway+++04621///NOD-like receptor signaling pathway+++04139///Mitophagy - yeast","H01900///Encephalopathy due to defective mitochondrial and peroxisomal fission","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R02918///L-Tyrosine:tRNA(Tyr) ligase (AMP-forming) ATP + L-Tyrosine + tRNA(Tyr) <=> AMP + Diphosphate + L-Tyrosyl-tRNA(Tyr)","GO:0045202///synapse+++GO:0099073///mitochondrion-derived vesicle+++GO:0098835///presynaptic endocytic zone membrane+++GO:0032991///protein-containing complex+++GO:0030672///synaptic vesicle membrane+++GO:0005874///microtubule+++GO:0031966///mitochondrial membrane+++GO:0030054///cell junction+++GO:0005777///peroxisome+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005905///clathrin-coated pit+++GO:0012505///endomembrane system+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0099503///secretory vesicle+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005903///brush border+++GO:0098794///postsynapse","GO:0003924///GTPase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0008289///lipid binding+++GO:0005525///GTP binding+++GO:0042803///protein homodimerization activity+++GO:0051433///BH2 domain binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0030276///clathrin binding+++GO:0008017///microtubule binding+++GO:0030742///GTP-dependent protein binding","GO:0012501///programmed cell death+++GO:0090141///positive regulation of mitochondrial fission+++GO:0043547///positive regulation of GTPase activity+++GO:0048488///synaptic vesicle endocytosis+++GO:0032459///regulation of protein oligomerization+++GO:0097194///execution phase of apoptosis+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:1904579///cellular response to thapsigargin+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0007005///mitochondrion organization+++GO:0090149///mitochondrial membrane fission+++GO:0070584///mitochondrion morphogenesis+++GO:0070585///protein localization to mitochondrion+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0036466///synaptic vesicle recycling via endosome+++GO:1990910///response to hypobaric hypoxia+++GO:0008637///apoptotic mitochondrial changes+++GO:1900063///regulation of peroxisome organization+++GO:0000266///mitochondrial fission+++GO:0048312///intracellular distribution of mitochondria+++GO:0061025///membrane fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0050714///positive regulation of protein secretion+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0016559///peroxisome fission+++GO:0060047///heart contraction+++GO:2000302///positive regulation of synaptic vesicle exocytosis+++GO:0007029///endoplasmic reticulum organization+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:0071396///cellular response to lipid+++GO:1905395///response to flavonoid+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0006897///endocytosis+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0051260///protein homooligomerization+++GO:0001836///release of cytochrome c from mitochondria+++GO:1903578///regulation of ATP metabolic process+++GO:0051259///protein complex oligomerization+++GO:0051289///protein homotetramerization+++GO:0070266///necroptotic process+++GO:0043065///positive regulation of apoptotic process","dynamin 1 like","[DNM1L_HUMAN|Reviewed]RecName: Full=Dynamin-1-like protein; EC=3.6.5.5; AltName: Full=Dnm1p/Vps1p-like protein; Short=DVLP; AltName: Full=Dynamin family member proline-rich carboxyl-terminal domain less; Short=Dymple; AltName: Full=Dynamin-like protein; AltName: Full=Dynamin-like protein 4; AltName: Full=Dynamin-like protein IV; Short=HdynIV; AltName: Full=Dynamin-related protein 1;+++[B4DDQ3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000396030}; SubName: Full=cDNA FLJ59840, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG56814.1};+++[B4DPZ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000390090}; SubName: Full=cDNA FLJ59948, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG60761.1};+++[B4DYR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56381, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG63828.1};+++[D3DUW5_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_c {ECO:0000313|EMBL:EAW88523.1};+++[D3DUW6_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_f {ECO:0000313|EMBL:EAW88527.1};+++[D3DUW7_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_a {ECO:0000313|EMBL:EAW88525.1};+++[F8VR28_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000450401};+++[F8VUJ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447845}; Flags: Fragment;+++[F8VYL3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448936};+++[F8VZ52_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447788}; Flags: Fragment;+++[F8W1W3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447013}; Flags: Fragment;+++[G8JLD5_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000350948};+++[H0YHY4_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448105}; Flags: Fragment;+++[H0YI79_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448802}; Flags: Fragment;+++[Q32Q67_HUMAN|Unreviewed]SubName: Full=DNM1L protein {ECO:0000313|EMBL:AAI07764.1}; Flags: Fragment;"]
[1006,"'CDH8'",159,87,103,116.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0043083///synaptic cleft+++GO:0097060///synaptic membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043679///axon terminus+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0016342///catenin complex","GO:0042802///identical protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding","GO:0007268///chemical synaptic transmission+++GO:0007043///cell-cell junction assembly+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0009409///response to cold+++GO:0050807///regulation of synapse organization+++GO:0035249///synaptic transmission, glutamatergic+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 8","[CADH8_HUMAN|Reviewed]RecName: Full=Cadherin-8; Flags: Precursor;+++[J3KRI5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462018};+++[J3KT81_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462847}; Flags: Fragment;+++[J3KTG8_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462976}; Flags: Fragment;+++[J3QKW5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463266};+++[J3QLE6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463511};+++[L8E7B0_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43150.1};+++[L8E8U5_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43151.1};+++[Q3LID3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla04261 {ECO:0000313|EMBL:BAE45735.1}; Flags: Fragment;+++[X6R3Y6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000299345};"]
[10060,"'ABCC9'",351.22,512.23,370.18,411.21,"02010///ABC transporters","H00294///Dilated cardiomyopathy (DCM)+++H00731///Atrial fibrillation",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0042383///sarcolemma+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0008282///inward rectifying potassium channel","GO:0044325///ion channel binding+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0015459///potassium channel regulator activity+++GO:0008281///sulfonylurea receptor activity+++GO:0005524///ATP binding+++GO:0005267///potassium channel activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005215///transporter activity","GO:1990573///potassium ion import across plasma membrane+++GO:0055085///transmembrane transport+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0006813///potassium ion transport+++GO:0051607///defense response to virus+++GO:0042493///response to drug","ATP binding cassette subfamily C member 9","[ABCC9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family C member 9; AltName: Full=Sulfonylurea receptor 2;+++[A0A024RAV7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW96456.1};+++[G3V1N6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000442604}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_a {ECO:0000313|EMBL:EAW96452.1};+++[H0YFV4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000440521}; Flags: Fragment;+++[K4DI86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_e {ECO:0000313|EMBL:EAW96458.1};+++[Q8N4N7_HUMAN|Unreviewed]SubName: Full=ABCC9 protein {ECO:0000313|EMBL:AAH33804.1}; SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000317518};"]
[10061,"'ABCF2'",1252,1300,1207,1253,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005740///mitochondrial envelope+++GO:0000786///nucleosome+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0005215///transporter activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity",null,"ATP binding cassette subfamily F member 2","[ABCF2_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family F member 2; AltName: Full=Iron-inhibited ABC transporter 2;+++[A0A090N7X1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24508.1};+++[A0A090N7Y2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24507.1};+++[C9JHK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000395785}; Flags: Fragment;+++[C9JZV3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000419720}; Flags: Fragment;+++[L0R4T3_HUMAN|Unreviewed]RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};"]
[10062,"'NR1H3'",90,145,131,122,"03320///PPAR signaling pathway+++05160///Hepatitis C+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease (NAFLD)",{"$nulls":3},"GO:0005634///nucleus+++GO:0043235///receptor complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0004879///nuclear receptor activity+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0038023///signaling receptor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003713///transcription coactivator activity+++GO:0015485///cholesterol binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0032810///sterol response element binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity","GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010887///negative regulation of cholesterol storage+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0090341///negative regulation of secretion of lysosomal enzymes+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0050728///negative regulation of inflammatory response+++GO:0042632///cholesterol homeostasis+++GO:2000325///regulation of nuclear receptor transcription coactivator activity+++GO:0055092///sterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0055088///lipid homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0048550///negative regulation of pinocytosis+++GO:0043031///negative regulation of macrophage activation+++GO:0045861///negative regulation of proteolysis+++GO:0010875///positive regulation of cholesterol efflux+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032570///response to progesterone+++GO:0043277///apoptotic cell clearance+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032369///negative regulation of lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0070328///triglyceride homeostasis+++GO:0044255///cellular lipid metabolic process","nuclear receptor subfamily 1 group H member 3","[NR1H3_HUMAN|Reviewed]RecName: Full=Oxysterols receptor LXR-alpha; AltName: Full=Liver X receptor alpha; AltName: Full=Nuclear receptor subfamily 1 group H member 3;+++[B4DXU5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56172, highly similar to Oxysterols receptor LXR-alpha {ECO:0000313|EMBL:BAG63507.1};+++[B5MBY7_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000385073};+++[B6ZGS8_HUMAN|Unreviewed]SubName: Full=Liver X receptor alpha {ECO:0000313|EMBL:BAH02289.1};+++[C9J2C8_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000412636}; Flags: Fragment;+++[C9J4R0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000391005}; Flags: Fragment;+++[C9JBS2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403696}; Flags: Fragment;+++[C9JCS0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000415591}; Flags: Fragment;+++[C9JEC2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000396132}; Flags: Fragment;+++[C9JJ16_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403798}; Flags: Fragment;+++[C9JTS4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000413095}; Flags: Fragment;+++[E9PID2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000432073};+++[E9PLL4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000433271};+++[E9PPA1_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000434650}; Flags: Fragment;+++[F1D8N1_HUMAN|Unreviewed]SubName: Full=Liver X nuclear receptor alpha variant 1 {ECO:0000313|EMBL:ADZ17330.1};+++[F8WC63_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000406692};+++[F8WEY6_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000407716};"]
[10063,"'COX17'",212,149,166,175.666666666667,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00154///Cytochrome c oxidase",null,"GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0016531///copper chaperone activity+++GO:0046872///metal ion binding+++GO:0005507///copper ion binding+++GO:1903136///cuprous ion binding+++GO:0005515///protein binding","GO:1904960///positive regulation of cytochrome-c oxidase activity+++GO:0006825///copper ion transport+++GO:0006091///generation of precursor metabolites and energy+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation","cytochrome c oxidase copper chaperone COX17","[COX17_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase copper chaperone;+++[C9J8T6_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417651}; SubName: Full=HCG2022684, isoform CRA_b {ECO:0000313|EMBL:EAW79546.1};+++[H7C4E5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417120}; Flags: Fragment;+++[H7C5P5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000420406}; Flags: Fragment;"]
[100631383,"'FAM47E-STBD1'",23.19,19.68,36.98,26.6166666666667,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"FAM47E-STBD1 readthrough","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[D6RA91_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000423044}; Flags: Fragment;+++[F6W5V1_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000425528};"]
[100652748,"'TIMM23B'",162.08,175.14,129.24,155.486666666667,"04212///Longevity regulating pathway - worm",{"$nulls":3},"GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005575///cellular_component+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0008320///protein transmembrane transporter activity","GO:0006886///intracellular protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0008150///biological_process+++GO:0015031///protein transport","translocase of inner mitochondrial membrane 23 homolog B","[TI23B_HUMAN|Reviewed]RecName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B;+++[B4DDK6_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000389331}; SubName: Full=cDNA FLJ60010, moderately similar to Mitochondrial import inner membrane translocase subunit Tim23 {ECO:0000313|EMBL:BAG56767.1};+++[M0QZG8_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000470535};+++[S4R2X5_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000473724};"]
[100652777,"'LOC100652777'",0,0,1.29,0.43,"04014///Ras signaling pathway+++00592///alpha-Linolenic acid metabolism+++04972///Pancreatic secretion+++04975///Fat digestion and absorption+++00590///Arachidonic acid metabolism+++00565///Ether lipid metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++04270///Vascular smooth muscle contraction+++00591///Linoleic acid metabolism+++00564///Glycerophospholipid metabolism",null,null,"R07387///plasmanylcholine 2-acylhydrolase 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate+++R01317///phosphatidylcholine 2-acylhydrolase Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate+++R07064///phosphatidylcholine 2-acylhydrolase Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate+++R02053///phosphatidylethanolamine 2-acylhydrolase Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid+++R07859///Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid+++R01315///phosphatidylcholine 2-acylhydrolase Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid+++R07379///plasmenylethanolamine 2-acylhydrolase O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate","GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0005509///calcium ion binding+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0004620///phospholipase activity+++GO:0004623///phospholipase A2 activity","GO:0016042///lipid catabolic process+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0036149///phosphatidylinositol acyl-chain remodeling+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0051977///lysophospholipid transport+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0019369///arachidonic acid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0010884///positive regulation of lipid storage+++GO:0042632///cholesterol homeostasis+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0090370///negative regulation of cholesterol efflux+++GO:0050482///arachidonic acid secretion+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0043030///regulation of macrophage activation+++GO:0007411///axon guidance","group 10 secretory phospholipase A2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PA2GF_HUMAN|diamond]RecName: Full=Group IIF secretory phospholipase A2; Short=GIIF sPLA2; Short=sPLA2-IIF; EC=3.1.1.4; AltName: Full=Phosphatidylcholine 2-acylhydrolase 2F; Flags: Precursor;+++[PA2GX_HUMAN|diamond]RecName: Full=Group 10 secretory phospholipase A2; EC=3.1.1.4; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor;+++[PA2GX_MOUSE|diamond]RecName: Full=Group 10 secretory phospholipase A2; EC=3.1.1.4; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor;+++[PA2GX_RAT|diamond]RecName: Full=Group 10 secretory phospholipase A2; EC=3.1.1.4; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor;+++[PA2V_MEIAT|diamond]RecName: Full=Phospholipase A2 {ECO:0000303|PubMed:28366739}; Short=PLA2 {ECO:0000303|PubMed:28366739}; EC=3.1.1.4; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10 {ECO:0000250|UniProtKB:O15496}; Flags: Precursor;"]
[100652824,"'KIAA2012'",3,0,1,1.33333333333333,"05225///Hepatocellular carcinoma+++04390///Hippo signaling pathway+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04150///mTOR signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05166///HTLV-I infection+++05165///Human papillomavirus infection+++04916///Melanogenesis+++04310///Wnt signaling pathway+++05224///Breast cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer","H00048///Hepatocellular carcinoma+++H00031///Breast cancer","M00677///Wnt signaling",null,"GO:0055038///recycling endosome membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0030165///PDZ domain binding+++GO:0042813///Wnt-activated receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017147///Wnt-protein binding+++GO:0005109///frizzled binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding","GO:0033077///T cell differentiation in thymus+++GO:0019827///stem cell population maintenance+++GO:0048103///somatic stem cell division+++GO:0030182///neuron differentiation+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0042327///positive regulation of phosphorylation+++GO:0060231///mesenchymal to epithelial transition+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0046330///positive regulation of JNK cascade+++GO:2000726///negative regulation of cardiac muscle cell differentiation+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0071300///cellular response to retinoic acid+++GO:0060070///canonical Wnt signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0042666///negative regulation of ectodermal cell fate specification","KIAA2012","[K2012_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA2012 {ECO:0000305};+++[A0A1B0GV91_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000490419}; Flags: Fragment;+++[H7C5G6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000419834};"]
[100652833,"'LOC100652833'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"putative POM121-like protein 1-like","[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[100652901,"'LOC100652901'",11,40.99,17.99,23.3266666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0010494///cytoplasmic stress granule","GO:0003727///single-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding","GO:0032197///transposition, RNA-mediated","uncharacterized LOC100652901","[Q6ZNX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26942 fis, clone RCT07464 {ECO:0000313|EMBL:BAC85354.1};"]
[100653049,"'LOC100653049'",0,1,0,0.333333333333333,"04915///Estrogen signaling pathway","H00708///Naegeli-Franceschetti-Jadassohn syndrome+++H00738///Ichthyosis with confetti+++H00796///Dermatopathia pigmentosa reticularis+++H00667///Woolly hair+++H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00726///Meesmann corneal dystrophy+++H00584///Epidermolysis bullosa simplex+++H00684///Pachyonychia congenita+++H00723///Non-epidermolytic palmoplantar keratoderma (NEPPK)+++H01673///Palmoplantar keratoderma+++H00724///White sponge nevus",null,null,"GO:0005882///intermediate filament","GO:0005198///structural molecule activity","GO:0008544///epidermis development+++GO:0031424///keratinization+++GO:0070268///cornification","keratin, type I cuticular Ha4","[KRT34_HUMAN|Reviewed]RecName: Full=Keratin, type I cuticular Ha4; AltName: Full=Hair keratin, type I Ha4; AltName: Full=Keratin-34; Short=K34;+++[A0A140TA62_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000459812};"]
[100653133,"'LOC100653133'",0,1,0,0.333333333333333,{"$nulls":7},"golgin subfamily A member 6-like protein 1","[GG6L1_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 1;+++[GG6L2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 2;+++[GG6L6_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 6;+++[GG6L7_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 7 {ECO:0000305};+++[GG6LV_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};"]
[100653515,"'CEP295NL'",6,6,2,4.66666666666667,{"$nulls":4},"GO:0005929///cilium+++GO:0042995///cell projection","GO:0008191///metalloendopeptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity","CEP295 N-terminal like","[C295L_HUMAN|Reviewed]RecName: Full=CEP295 N-terminal-like protein {ECO:0000305}; AltName: Full=KIAA1731 N-terminal like protein {ECO:0000312|HGNC:HGNC:44659};+++[K7EL90_HUMAN|Unreviewed]SubName: Full=CEP295 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000465968}; Flags: Fragment;"]
[10066,"'SCAMP2'",2079,2070,2011,2053.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0055038///recycling endosome membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0032588///trans-Golgi network membrane+++GO:0030133///transport vesicle","GO:0005515///protein binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","secretory carrier membrane protein 2","[SCAM2_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 2; Short=Secretory carrier membrane protein 2;+++[A0A140VK92_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[A8K769_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BMN2_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BN93_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BPL9_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BQW2_HUMAN|Unreviewed]SubName: Full=Secretory carrier-associated membrane protein 2 {ECO:0000313|Ensembl:ENSP00000455963};+++[H3BUB6_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BV04_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[Q6IBK3_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};"]
[10067,"'SCAMP3'",2072,2170,2031,2091,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032588///trans-Golgi network membrane","GO:0031625///ubiquitin protein ligase binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","secretory carrier membrane protein 3","[SCAM3_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 3; Short=Secretory carrier membrane protein 3;+++[Q6FHJ5_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;"]
[10068,"'IL18BP'",42,87,84,71,{"$nulls":4},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0042007///interleukin-18 binding+++GO:0048019///receptor antagonist activity","GO:0070301///cellular response to hydrogen peroxide+++GO:0032496///response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor+++GO:0042088///T-helper 1 type immune response+++GO:0071345///cellular response to cytokine stimulus+++GO:1900116///extracellular negative regulation of signal transduction+++GO:0035655///interleukin-18-mediated signaling pathway","interleukin 18 binding protein","[I18BP_HUMAN|Reviewed]RecName: Full=Interleukin-18-binding protein; Short=IL-18BP; AltName: Full=Tadekinig-alfa; Flags: Precursor;+++[A0A024R5G2_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_d {ECO:0000313|EMBL:EAW74817.1};+++[A0A024R5I1_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_c {ECO:0000313|EMBL:EAW74820.1};+++[A0A024R5M7_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_b {ECO:0000313|EMBL:EAW74819.1};+++[G3V1C5_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW74812.1}; SubName: Full=Interleukin-18-binding protein {ECO:0000313|Ensembl:ENSP00000434717};"]
[10069,"'RWDD2B'",187,154,166,169,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","RWD domain containing 2B","[RWD2B_HUMAN|Reviewed]RecName: Full=RWD domain-containing protein 2B;"]
[10071,"'MUC12'",1,2,3,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0001558///regulation of cell growth+++GO:0016266///O-glycan processing+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","mucin 12, cell surface associated","[MUC12_HUMAN|Reviewed]RecName: Full=Mucin-12; Short=MUC-12; AltName: Full=Mucin-11; Short=MUC-11; Flags: Precursor;+++[A1L198_HUMAN|Unreviewed]SubName: Full=MUC12 protein {ECO:0000313|EMBL:AAI27878.1}; Flags: Fragment;+++[H7BXN1_HUMAN|Unreviewed]SubName: Full=Mucin-12 {ECO:0000313|Ensembl:ENSP00000306919}; Flags: Fragment;+++[L8E898_HUMAN|Unreviewed]SubName: Full=Alternative protein MUC12 {ECO:0000313|EMBL:CCQ42956.1};"]
[10072,"'DPP3'",1146,1185,1189,1173.33333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016607///nuclear speck","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004177///aminopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008237///metallopeptidase activity+++GO:0008239///dipeptidyl-peptidase activity","GO:0006508///proteolysis","dipeptidyl peptidase 3","[DPP3_HUMAN|Reviewed]RecName: Full=Dipeptidyl peptidase 3; EC=3.4.14.4 {ECO:0000269|PubMed:11209758, ECO:0000269|PubMed:1515063, ECO:0000269|PubMed:3233187, ECO:0000269|PubMed:9425109}; AltName: Full=Dipeptidyl aminopeptidase III; AltName: Full=Dipeptidyl arylamidase III; AltName: Full=Dipeptidyl peptidase III; Short=DPP III; AltName: Full=Enkephalinase B;+++[E9PKK8_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000431606}; Flags: Fragment;+++[E9PNX5_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000437101}; Flags: Fragment;+++[E9PPK9_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000432618}; Flags: Fragment;+++[E9PQ14_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000434518}; Flags: Fragment;+++[E9PQF2_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000436820}; Flags: Fragment;+++[G3V180_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[G3V1D3_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[Q5JPB8_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};"]
[10073,"'SNUPN'",114,159,187,153.333333333333,"03013///RNA transport",{"$nulls":3},"GO:0005829///cytosol+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0061608///nuclear import signal receptor activity+++GO:0005515///protein binding","GO:0006606///protein import into nucleus+++GO:0061015///snRNA import into nucleus+++GO:0000387///spliceosomal snRNP assembly+++GO:0051170///import into nucleus","snurportin 1","[SPN1_HUMAN|Reviewed]RecName: Full=Snurportin-1; AltName: Full=RNA U transporter 1;+++[H3BQR0_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000455894}; Flags: Fragment;+++[H3BRI5_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456260}; Flags: Fragment;+++[H3BSK1_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456742}; Flags: Fragment;+++[H3BTA6_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457093}; Flags: Fragment;+++[H3BUB4_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457562}; Flags: Fragment;"]
[10075,"'HUWE1'",8343,10263,8549,9051.66666666667,"04120///Ubiquitin mediated proteolysis","H00658///Syndromic X-linked mental retardation",null,null,"GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0003723///RNA binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006281///DNA repair+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0043312///neutrophil degranulation+++GO:0006284///base-excision repair+++GO:0000209///protein polyubiquitination+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016574///histone ubiquitination","HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase","[HUWE1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase HUWE1; EC=2.3.2.26; AltName: Full=ARF-binding protein 1; Short=ARF-BP1; AltName: Full=HECT, UBA and WWE domain-containing protein 1; AltName: Full=HECT-type E3 ubiquitin transferase HUWE1; AltName: Full=Homologous to E6AP carboxyl terminus homologous protein 9; Short=HectH9; AltName: Full=Large structure of UREB1; Short=LASU1; AltName: Full=Mcl-1 ubiquitin ligase E3; Short=Mule; AltName: Full=Upstream regulatory element-binding protein 1; Short=URE-B1; Short=URE-binding protein 1;+++[A0A024R9U8_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW93163.1};+++[A0A024R9W5_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW93166.1};+++[A0A024R9Y3_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW93165.1};+++[A0A087X146_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000483891}; Flags: Fragment;+++[A0A087X1S3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000484417}; Flags: Fragment;+++[A0A1B0GXC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000413651}; Flags: Fragment;+++[H0Y659_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000403236}; Flags: Fragment;+++[L8E996_HUMAN|Unreviewed]SubName: Full=Alternative protein HUWE1 {ECO:0000313|EMBL:CCQ43744.1};+++[Q3B7K0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAI07577.1}; Flags: Fragment;+++[Q5H924_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42656.1}; Flags: Fragment;+++[Q5H935_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42644.1}; Flags: Fragment;+++[Q5H962_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42353.1};+++[Q5H963_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42352.1}; Flags: Fragment;+++[Q5H964_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42351.1}; Flags: Fragment;+++[Q8IWJ0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAH38184.1}; Flags: Fragment;"]
[10076,"'PTPRU'",2852,3127,2837,2938.66666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:0030027///lamellipodium+++GO:0098978///glutamatergic synapse+++GO:0005911///cell-cell junction+++GO:0099061///integral component of postsynaptic density membrane+++GO:0016324///apical plasma membrane+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0098982///GABA-ergic synapse+++GO:0030426///growth cone+++GO:0005887///integral component of plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0008013///beta-catenin binding+++GO:0017147///Wnt-protein binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0016787///hydrolase activity","GO:0034109///homotypic cell-cell adhesion+++GO:0016311///dephosphorylation+++GO:0031100///animal organ regeneration+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0007185///transmembrane receptor protein tyrosine phosphatase signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0032835///glomerulus development+++GO:0002548///monocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0034394///protein localization to cell surface+++GO:0007155///cell adhesion+++GO:0050807///regulation of synapse organization+++GO:0006470///protein dephosphorylation+++GO:0030154///cell differentiation+++GO:0010977///negative regulation of neuron projection development+++GO:0030032///lamellipodium assembly+++GO:0007411///axon guidance+++GO:0030336///negative regulation of cell migration+++GO:0090260///negative regulation of retinal ganglion cell axon guidance+++GO:0003105///negative regulation of glomerular filtration+++GO:0003093///regulation of glomerular filtration+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0008285///negative regulation of cell proliferation+++GO:0036060///slit diaphragm assembly","protein tyrosine phosphatase, receptor type U","[PTPRU_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase U; Short=R-PTP-U; EC=3.1.3.48; AltName: Full=Pancreatic carcinoma phosphatase 2; Short=PCP-2; AltName: Full=Protein-tyrosine phosphatase J; Short=PTP-J; Short=hPTP-J; AltName: Full=Protein-tyrosine phosphatase pi; Short=PTP pi; AltName: Full=Protein-tyrosine phosphatase receptor omicron; Short=PTP-RO; AltName: Full=Receptor-type protein-tyrosine phosphatase psi; Short=R-PTP-psi; Flags: Precursor;+++[H0YH11_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[H0YH60_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[L8ECC6_HUMAN|Unreviewed]SubName: Full=Alternative protein PTPRU {ECO:0000313|EMBL:CCQ43332.1};+++[Q9P0U2_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase {ECO:0000313|EMBL:AAF67472.1};"]
[10077,"'TSPAN32'",2,2,4,2.66666666666667,{"$nulls":4},"GO:0070442///integrin alphaIIb-beta3 complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0009986///cell surface+++GO:0031225///anchored component of membrane+++GO:0016020///membrane+++GO:0033017///sarcoplasmic reticulum membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003674///molecular_function","GO:0007010///cytoskeleton organization+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007599///hemostasis+++GO:0006471///protein ADP-ribosylation+++GO:0007596///blood coagulation+++GO:0070527///platelet aggregation+++GO:0007267///cell-cell signaling+++GO:0042832///defense response to protozoan+++GO:0008285///negative regulation of cell proliferation+++GO:0018120///peptidyl-arginine ADP-ribosylation+++GO:0050688///regulation of defense response to virus","tetraspanin 32","[TSN32_HUMAN|Reviewed]RecName: Full=Tetraspanin-32; Short=Tspan-32; AltName: Full=Protein Phemx;+++[D3YTD1_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000405205};+++[F8WB10_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000405001};+++[F8WCN6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000343285};+++[G3XAG6_HUMAN|Unreviewed]SubName: Full=Tetraspanin 32, isoform CRA_e {ECO:0000313|EMBL:EAX02502.1}; SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000370509}; Flags: Fragment;+++[Q7Z5M9_HUMAN|Unreviewed]SubName: Full=Pan-hematopoietic expression protein {ECO:0000313|EMBL:AAP76185.1};"]
[10078,"'TSSC4'",363,362,382,369,{"$nulls":5},"GO:0005515///protein binding",null,"tumor suppressing subtransferable candidate 4","[TSSC4_HUMAN|Reviewed]RecName: Full=Protein TSSC4; AltName: Full=Tumor-suppressing STF cDNA 4 protein; AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein;+++[A0A024RCB9_HUMAN|Unreviewed]SubName: Full=Tumor suppressing subtransferable candidate 4, isoform CRA_a {ECO:0000313|EMBL:EAX02513.1};+++[A6NCC9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000370380};+++[C9JDU0_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000403475}; Flags: Fragment;+++[C9JHT9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000396925}; Flags: Fragment;+++[C9JJV1_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000416937}; Flags: Fragment;+++[E9PL88_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000431430}; Flags: Fragment;+++[E9PME3_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000435013}; Flags: Fragment;"]
[10079,"'ATP9A'",829,812,754,798.333333333333,null,"H00624///Familial cholestasis",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005769///early endosome+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding","GO:0006897///endocytosis+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport","ATPase phospholipid transporting 9A (putative)","[ATP9A_HUMAN|Reviewed]RecName: Full=Probable phospholipid-transporting ATPase IIA; EC=3.6.3.1; AltName: Full=ATPase class II type 9A;+++[A0A0A0MR22_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[B4DR18_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[Q2NLD0_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033}; Flags: Fragment;+++[Q96B35_HUMAN|Unreviewed]SubName: Full=ATP9A protein {ECO:0000313|EMBL:AAH16044.1}; Flags: Fragment;"]
[1008,"'CDH10'",94,79,85,86,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099059///integral component of presynaptic active zone membrane+++GO:0016342///catenin complex+++GO:0098982///GABA-ergic synapse+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0099060///integral component of postsynaptic specialization membrane","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 10","[CAD10_HUMAN|Reviewed]RecName: Full=Cadherin-10; AltName: Full=T2-cadherin; Flags: Precursor;+++[D6RJG0_HUMAN|Unreviewed]SubName: Full=Cadherin-10 {ECO:0000313|Ensembl:ENSP00000425653};+++[L8ECD4_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH10 {ECO:0000313|EMBL:CCQ43372.1};+++[X5D8X5_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform A {ECO:0000313|EMBL:AHW56448.1}; SubName: Full=Cadherin 10, type 2 (T2-cadherin) {ECO:0000313|EMBL:EAX10742.1}; Flags: Fragment;+++[X5DNG6_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform B {ECO:0000313|EMBL:AHW56446.1}; Flags: Fragment;+++[X5DQT8_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform C {ECO:0000313|EMBL:AHW56447.1}; Flags: Fragment;"]
[10081,"'PDCD7'",356,382,316,351.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005689///U12-type spliceosomal complex",null,"GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0051384///response to glucocorticoid+++GO:0000398///mRNA splicing, via spliceosome","programmed cell death 7","[PDCD7_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 7; AltName: Full=ES18; Short=hES18;+++[A3KMF9_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAI31705.1}; Flags: Fragment;+++[H3BT73_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 7 {ECO:0000313|Ensembl:ENSP00000457053}; Flags: Fragment;+++[Q569I4_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAH92464.1}; Flags: Fragment;+++[Q6IEG3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 7, isoform CRA_a {ECO:0000313|EMBL:EAW77713.1}; SubName: Full=U11/U12 snRNP 59K {ECO:0000313|EMBL:DAA05494.1};"]
[10082,"'GPC6'",868,823,952,881,null,"H02154///Omodysplasia+++H00493///Heparan sulfate proteoglycan gene defects",null,null,"GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0005634///nucleus+++GO:0062023///collagen-containing extracellular matrix+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0046658///anchored component of plasma membrane+++GO:0043202///lysosomal lumen+++GO:0005796///Golgi lumen+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding+++GO:1904929///coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway","GO:0006027///glycosaminoglycan catabolic process+++GO:0001523///retinoid metabolic process+++GO:0016477///cell migration+++GO:0009966///regulation of signal transduction+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane","glypican 6","[GPC6_HUMAN|Reviewed]RecName: Full=Glypican-6; Contains: RecName: Full=Secreted glypican-6; Flags: Precursor;+++[A0A087WT82_HUMAN|Unreviewed]SubName: Full=Glypican-6 {ECO:0000313|Ensembl:ENSP00000477667};"]
[100820829,"'MYZAP'",5,7,10,7.33333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0030018///Z disc","GO:0005515///protein binding","GO:0035556///intracellular signal transduction","myocardial zonula adherens protein","[MYZAP_HUMAN|Reviewed]RecName: Full=Myocardial zonula adherens protein; AltName: Full=GRINL1A upstream protein; Short=Gup; Flags: Precursor;+++[A0A024R5W4_HUMAN|Unreviewed]SubName: Full=HCG40688, isoform CRA_a {ECO:0000313|EMBL:EAW77523.1};+++[H0YCD3_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000431396}; Flags: Fragment;+++[H3BTD5_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000457126}; Flags: Fragment;"]
[10083,"'USH1C'",0,1,0,0.333333333333333,null,"H00605///Deafness, autosomal recessive+++H00779///Usher syndrome (US)",null,null,"GO:0002142///stereocilia ankle link complex+++GO:0045202///synapse+++GO:0005903///brush border+++GO:0005902///microvillus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0032420///stereocilium+++GO:0005886///plasma membrane+++GO:0001917///photoreceptor inner segment+++GO:0032391///photoreceptor connecting cilium+++GO:0005737///cytoplasm+++GO:0001750///photoreceptor outer segment+++GO:0002141///stereocilia ankle link+++GO:0032426///stereocilium tip","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0030507///spectrin binding","GO:0034622///cellular protein-containing complex assembly+++GO:0050953///sensory perception of light stimulus+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0042472///inner ear morphogenesis+++GO:1904106///protein localization to microvillus+++GO:0045494///photoreceptor cell maintenance+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0030046///parallel actin filament bundle assembly+++GO:0007605///sensory perception of sound+++GO:1904970///brush border assembly+++GO:0032532///regulation of microvillus length+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0050957///equilibrioception+++GO:0051017///actin filament bundle assembly+++GO:0030154///cell differentiation","USH1 protein network component harmonin","[USH1C_HUMAN|Reviewed]RecName: Full=Harmonin; AltName: Full=Antigen NY-CO-38/NY-CO-37; AltName: Full=Autoimmune enteropathy-related antigen AIE-75; AltName: Full=Protein PDZ-73; AltName: Full=Renal carcinoma antigen NY-REN-3; AltName: Full=Usher syndrome type-1C protein;+++[A0A0S2Z4U9_HUMAN|Unreviewed]SubName: Full=Usher syndrome 1C (Autosomal recessive, severe), isoform CRA_d {ECO:0000313|EMBL:EAW68434.1}; SubName: Full=Usher syndrome 1C isoform 2 {ECO:0000313|EMBL:ALQ33957.1}; Flags: Fragment;+++[A0A0S2Z4V1_HUMAN|Unreviewed]SubName: Full=Usher syndrome 1C (Autosomal recessive, severe), isoform CRA_a {ECO:0000313|EMBL:EAW68431.1}; SubName: Full=Usher syndrome 1C isoform 1 {ECO:0000313|EMBL:ALQ33956.1}; Flags: Fragment;+++[E9PNW1_HUMAN|Unreviewed]SubName: Full=Harmonin {ECO:0000313|Ensembl:ENSP00000437128}; Flags: Fragment;"]
[10084,"'PQBP1'",614,663,602,626.333333333333,"03040///Spliceosome","H01913///Renpenning syndrome+++H00480///Non-syndromic X-linked mental retardation","M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0010494///cytoplasmic stress granule+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071598///neuronal ribonucleoprotein granule","GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043021///ribonucleoprotein complex binding","GO:0006355///regulation of transcription, DNA-templated+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0032481///positive regulation of type I interferon production+++GO:0031175///neuron projection development+++GO:0002218///activation of innate immune response+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071360///cellular response to exogenous dsRNA+++GO:0002230///positive regulation of defense response to virus by host+++GO:0008380///RNA splicing+++GO:0051607///defense response to virus+++GO:0043484///regulation of RNA splicing+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0048814///regulation of dendrite morphogenesis","polyglutamine binding protein 1","[PQBP1_HUMAN|Reviewed]RecName: Full=Polyglutamine-binding protein 1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; Short=PQBP-1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; AltName: Full=38 kDa nuclear protein containing a WW domain {ECO:0000303|PubMed:10198427}; Short=Npw38 {ECO:0000303|PubMed:10198427}; AltName: Full=Polyglutamine tract-binding protein 1 {ECO:0000303|PubMed:10332029};+++[A0A0S2Z4V5_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33958.1}; SubName: Full=Polyglutamine binding protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW50737.1}; Flags: Fragment;+++[A0A0S2Z556_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33959.1}; Flags: Fragment;+++[H7C053_HUMAN|Unreviewed]SubName: Full=Polyglutamine-binding protein 1 {ECO:0000313|Ensembl:ENSP00000393013}; Flags: Fragment;+++[Q4VY28_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein variant 12 {ECO:0000313|EMBL:CAJ00551.1}; Flags: Fragment;"]
[10085,"'EDIL3'",2923,2579,2635,2712.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:1903561///extracellular vesicle","GO:0005201///extracellular matrix structural constituent+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0010811///positive regulation of cell-substrate adhesion","EGF like repeats and discoidin domains 3","[EDIL3_HUMAN|Reviewed]RecName: Full=EGF-like repeat and discoidin I-like domain-containing protein 3; AltName: Full=Developmentally-regulated endothelial cell locus 1 protein; AltName: Full=Integrin-binding protein DEL1; Flags: Precursor;"]
[100861412,"'FSBP'",58.73,58.8,52.95,56.8266666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","fibrinogen silencer binding protein","[FSBP_HUMAN|Reviewed]RecName: Full=Fibrinogen silencer-binding protein;+++[J3KSW4_HUMAN|Unreviewed]SubName: Full=Fibrinogen silencer-binding protein {ECO:0000313|Ensembl:ENSP00000462684};"]
[100862671,"'TMEM265'",104,113,117,111.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009607///response to biotic stimulus","transmembrane protein 265","[TM265_HUMAN|Reviewed]RecName: Full=Transmembrane protein 265 {ECO:0000312|HGNC:HGNC:51241};"]
[10087,"'COL4A3BP'",724,656,687,689,"05202///Transcriptional misregulation in cancer+++05213///Endometrial cancer+++05224///Breast cancer+++04140///Autophagy - animal+++05210///Colorectal cancer+++05220///Chronic myeloid leukemia+++05212///Pancreatic cancer+++05214///Glioma+++05216///Thyroid cancer+++04137///Mitophagy - animal+++05218///Melanoma+++05217///Basal cell carcinoma+++03460///Fanconi anemia pathway+++05226///Gastric cancer+++05225///Hepatocellular carcinoma+++05222///Small cell lung cancer+++05200///Pathways in cancer+++05223///Non-small cell lung cancer","H00773///Autosomal dominant mental retardation",null,null,"GO:0005581///collagen trimer+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005623///cell+++GO:0048471///perinuclear region of cytoplasm","GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0120017///intermembrane ceramide transfer activity+++GO:0008289///lipid binding+++GO:1902388///ceramide 1-phosphate transporter activity+++GO:0016301///kinase activity+++GO:1902387///ceramide 1-phosphate binding+++GO:0097001///ceramide binding+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0006869///lipid transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0003007///heart morphogenesis+++GO:0055088///lipid homeostasis+++GO:0001701///in utero embryonic development+++GO:0008283///cell proliferation+++GO:0006672///ceramide metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0120009///intermembrane lipid transfer+++GO:0007029///endoplasmic reticulum organization+++GO:0120012///intermembrane sphingolipid transfer+++GO:0035621///ER to Golgi ceramide transport+++GO:0035627///ceramide transport+++GO:0000902///cell morphogenesis+++GO:1902389///ceramide 1-phosphate transport+++GO:0070584///mitochondrion morphogenesis+++GO:0006936///muscle contraction+++GO:0007165///signal transduction+++GO:0006955///immune response","collagen type IV alpha 3 binding protein","[C43BP_HUMAN|Reviewed]RecName: Full=Collagen type IV alpha-3-binding protein; AltName: Full=Ceramide transfer protein {ECO:0000303|PubMed:14685229}; Short=hCERT; AltName: Full=Goodpasture antigen-binding protein; Short=GPBP; AltName: Full=START domain-containing protein 11; Short=StARD11; AltName: Full=StAR-related lipid transfer protein 11;+++[A0A024RAJ5_HUMAN|Unreviewed]SubName: Full=Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW95758.1};+++[A0A0A0MRE4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000350046}; Flags: Fragment;+++[A0A2R8Y3S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493565}; Flags: Fragment;+++[A0A2R8Y5G0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494760}; Flags: Fragment;+++[A0A2R8Y5H3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494810}; Flags: Fragment;+++[A0A2R8Y5S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494804};+++[A0A2R8Y773_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495798}; Flags: Fragment;+++[A0A2R8Y7C5_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496016};+++[A0A2R8Y7Q9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496462};+++[A0A2R8YCI0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493604};+++[A0A2R8YDX6_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495038}; Flags: Fragment;+++[A0A2R8YE18_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495172};+++[A0A2R8YE59_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494073}; Flags: Fragment;+++[A0A2R8YEA4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495430};+++[A0A2R8YEK8_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494424};+++[A0A2R8YFA1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494969}; Flags: Fragment;+++[A0A2R8YFI2_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496472};+++[A0A2U3TZL3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000369862}; Flags: Fragment;+++[H0Y9J1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000424244}; Flags: Fragment;"]
[100873985,"'MED14OS'",1,3,4,2.66666666666667,{"$nulls":7},"MED14 opposite strand","[M14OS_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein MED14OS {ECO:0000305}; AltName: Full=MED14 antisense gene protein 1 {ECO:0000305}; AltName: Full=MED14 opposite strand protein {ECO:0000312|HGNC:HGNC:40162};"]
[100885848,"'PTGES3L'",7.93,3.97,7.49,6.46333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0051879///Hsp90 protein binding+++GO:0051087///chaperone binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","prostaglandin E synthase 3 like","[PTG3L_HUMAN|Reviewed]RecName: Full=Putative protein PTGES3L; AltName: Full=Prostaglandin E synthase 3-like;+++[B9A003_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000386902};+++[C9JG77_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000404440}; Flags: Fragment;+++[H7C1Q7_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000467778}; Flags: Fragment;+++[K7N7A2_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000401675}; Flags: Fragment;"]
[100885850,"'PTGES3L-AARSD1'",5.13,13.24,1.19,6.52,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004813///alanine-tRNA ligase activity","GO:0006419///alanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation","PTGES3L-AARSD1 readthrough","[AASD1_HUMAN|Reviewed]RecName: Full=Alanyl-tRNA editing protein Aarsd1; AltName: Full=Alanyl-tRNA synthetase domain-containing protein 1;+++[C9J5N1_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000386254};+++[C9JUA3_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393780}; Flags: Fragment;+++[H7C054_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393019}; Flags: Fragment;+++[L7N2F6_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000407951}; Flags: Fragment;"]
[10089,"'KCNK7'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0022841///potassium ion leak channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity","GO:0006813///potassium ion transport+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport","potassium two pore domain channel subfamily K member 7","[KCNK7_HUMAN|Reviewed]RecName: Full=Potassium channel subfamily K member 7;+++[A0A024R5B0_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_c {ECO:0000313|EMBL:EAW74415.1};+++[A0A024R5F5_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_b {ECO:0000313|EMBL:EAW74414.1};+++[H0YCM4_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000431950}; Flags: Fragment;+++[H0YEB9_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000435449}; Flags: Fragment;+++[Q3MI97_HUMAN|Unreviewed]SubName: Full=KCNK7 protein {ECO:0000313|EMBL:AAI03812.2}; Flags: Fragment;+++[Q3SYI1_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7 {ECO:0000313|EMBL:AAI03811.1};"]
[1009,"'CDH11'",674,605,903,727.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01513///Retinoblastoma",null,null,"GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0070062///extracellular exosome+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse+++GO:0005737///cytoplasm","GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding","GO:0021957///corticospinal tract morphogenesis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0001503///ossification+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050804///modulation of chemical synaptic transmission+++GO:0001501///skeletal system development","cadherin 11","[CAD11_HUMAN|Reviewed]RecName: Full=Cadherin-11; AltName: Full=OSF-4; AltName: Full=Osteoblast cadherin; Short=OB-cadherin; Flags: Precursor;+++[A0A087X227_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000484650}; Flags: Fragment;+++[H3BP26_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455120}; Flags: Fragment;+++[H3BPQ2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455420}; Flags: Fragment;+++[H3BQB5_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455697}; Flags: Fragment;+++[H3BQH2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455779}; Flags: Fragment;+++[H3BR78_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456110}; Flags: Fragment;+++[H3BSM4_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456772}; Flags: Fragment;+++[H3BUU9_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000457812};+++[Q96CZ9_HUMAN|Unreviewed]SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast) {ECO:0000313|EMBL:AAH13609.1}; SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast), isoform CRA_c {ECO:0000313|EMBL:EAW83002.1};"]
[10090,"'UST'",43,35,30,36,"00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0050770///regulation of axonogenesis+++GO:0006477///protein sulfation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030010///establishment of cell polarity","uronyl 2-sulfotransferase","[UST_HUMAN|Reviewed]RecName: Full=Uronyl 2-sulfotransferase; EC=2.8.2.-;"]
[10092,"'ARPC5'",2911,2062,2250,2407.66666666667,"05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++04144///Endocytosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0034774///secretory granule lumen+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005885///Arp2/3 protein complex","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0030036///actin cytoskeleton organization+++GO:0030011///maintenance of cell polarity+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0051639///actin filament network formation+++GO:0016477///cell migration+++GO:0061024///membrane organization+++GO:0097581///lamellipodium organization+++GO:0061842///microtubule organizing center localization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0014909///smooth muscle cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0021769///orbitofrontal cortex development","actin related protein 2/3 complex subunit 5","[ARPC5_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5; AltName: Full=Arp2/3 complex 16 kDa subunit; Short=p16-ARC;+++[B1ALC0_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};+++[Q6IPM3_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};"]
[10093,"'ARPC4'",1634.27,1517.55,1582.53,1578.11666666667,"04144///Endocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton","GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0051015///actin filament binding+++GO:0030674///protein binding, bridging+++GO:0003779///actin binding","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0045010///actin nucleation+++GO:0030041///actin filament polymerization+++GO:0048013///ephrin receptor signaling pathway+++GO:0061024///membrane organization+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis","actin related protein 2/3 complex subunit 4","[ARPC4_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4; AltName: Full=Arp2/3 complex 20 kDa subunit; Short=p20-ARC;+++[F8WDD7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000395085};+++[F8WDW3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000414751};+++[R4GN08_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000473435}; Flags: Fragment;"]
[10094,"'ARPC3'",1546,1228,1291,1355,"05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++04144///Endocytosis+++05131///Shigellosis+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0031941///filamentous actin+++GO:0061850///growth cone leading edge+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0031252///cell leading edge+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0070358///actin polymerization-dependent cell motility","actin related protein 2/3 complex subunit 3","[ARPC3_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3; AltName: Full=Arp2/3 complex 21 kDa subunit; Short=p21-ARC;+++[C9JZD1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000413221}; Flags: Fragment;+++[F8VR50_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000446598}; Flags: Fragment;+++[Q2LE71_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000256|PIRNR:PIRNR016315}; AltName: Full=Arp2/3 complex 21 kDa subunit {ECO:0000256|PIRNR:PIRNR016315};"]
[10095,"'ARPC1B'",1280,1089,1218,1195.66666666667,"05131///Shigellosis+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0036284///tubulobulbar complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0032355///response to estradiol+++GO:0043627///response to estrogen+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization","actin related protein 2/3 complex subunit 1B","[ARC1B_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1B; AltName: Full=Arp2/3 complex 41 kDa subunit; AltName: Full=p41-ARC;+++[A4D275_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};+++[C9J4Z7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000410238}; Flags: Fragment;+++[C9J6C8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398110}; Flags: Fragment;+++[C9JBJ7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398620}; Flags: Fragment;+++[C9JEY1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403324}; Flags: Fragment;+++[C9JFG9_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403211}; Flags: Fragment;+++[C9JM51_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408758}; Flags: Fragment;+++[C9JQM8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000388802}; Flags: Fragment;+++[C9JTT6_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413067}; Flags: Fragment;+++[C9K057_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413173};+++[F8VXW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000399955};+++[F8WEB3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408508};+++[L8EAG6_HUMAN|Unreviewed]SubName: Full=Alternative protein ARPC1B {ECO:0000313|EMBL:CCQ43333.1};"]
[10096,"'ACTR3'",2971,2038,2224,2411,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0035861///site of double-strand break+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0030027///lamellipodium+++GO:0005911///cell-cell junction","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005524///ATP binding+++GO:0003779///actin binding","GO:0007163///establishment or maintenance of cell polarity+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0071346///cellular response to interferon-gamma+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070358///actin polymerization-dependent cell motility+++GO:0008356///asymmetric cell division+++GO:0060271///cilium assembly+++GO:0033206///meiotic cytokinesis+++GO:0007015///actin filament organization+++GO:0061024///membrane organization+++GO:0051321///meiotic cell cycle+++GO:0051653///spindle localization+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0048013///ephrin receptor signaling pathway+++GO:0030030///cell projection organization","ARP3 actin related protein 3 homolog","[ARP3_HUMAN|Reviewed]RecName: Full=Actin-related protein 3; AltName: Full=Actin-like protein 3;+++[A0A024RAI1_HUMAN|Unreviewed]SubName: Full=ARP3 actin-related protein 3 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW95180.1};+++[B4DXW1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000444987}; SubName: Full=cDNA FLJ51148, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63684.1}; SubName: Full=cDNA FLJ52434, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63523.1}; SubName: Full=cDNA, FLJ79112, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14584.1}; SubName: Full=cDNA, FLJ79295, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14767.1};+++[F8WDR7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000403125}; Flags: Fragment;+++[F8WE84_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000394213};+++[F8WEW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000407912};"]
[10097,"'ACTR2'",2504,1709,2073,2095.33333333333,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0014069///postsynaptic density+++GO:0035861///site of double-strand break+++GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071437///invadopodium+++GO:0030027///lamellipodium+++GO:0005856///cytoskeleton+++GO:0035578///azurophil granule lumen+++GO:0098794///postsynapse+++GO:0061825///podosome core+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0042995///cell projection+++GO:0030478///actin cap","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0051015///actin filament binding+++GO:0008092///cytoskeletal protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0061024///membrane organization+++GO:0033206///meiotic cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:0007015///actin filament organization+++GO:0043312///neutrophil degranulation+++GO:0008306///associative learning+++GO:0035902///response to immobilization stress+++GO:0045471///response to ethanol+++GO:0016482///cytosolic transport+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0008356///asymmetric cell division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining+++GO:0007163///establishment or maintenance of cell polarity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0060271///cilium assembly+++GO:0051321///meiotic cell cycle+++GO:0035984///cellular response to trichostatin A+++GO:0071346///cellular response to interferon-gamma+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0051653///spindle localization","ARP2 actin related protein 2 homolog","[ARP2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2; AltName: Full=Actin-like protein 2;+++[A0A1B0GWD0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490877};+++[A0A1B0GWH0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490923};+++[F5H6T1_HUMAN|Unreviewed]SubName: Full=ARP2 actin-related protein 2 homolog (Yeast), isoform CRA_d {ECO:0000313|EMBL:EAW99914.1}; SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000437383};+++[Q8IY98_HUMAN|Unreviewed]SubName: Full=ACTR2 protein {ECO:0000313|EMBL:AAH36253.1};"]
[10098,"'TSPAN5'",1138,977,814,976.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0019899///enzyme binding","GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane+++GO:0007166///cell surface receptor signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0045747///positive regulation of Notch signaling pathway","tetraspanin 5","[TSN5_HUMAN|Reviewed]RecName: Full=Tetraspanin-5; Short=Tspan-5; AltName: Full=Tetraspan NET-4; AltName: Full=Transmembrane 4 superfamily member 9;+++[B7Z317_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[D6R9N6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000423504}; Flags: Fragment;+++[D6RAR1_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000421808};+++[D6RBT5_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422548};+++[D6RGZ7_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000426248}; Flags: Fragment;+++[H0Y8W4_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422351}; Flags: Fragment;+++[Q6FHC5_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[10099,"'TSPAN3'",6559,5822,5653,6011.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway","H00287///Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0007166///cell surface receptor signaling pathway+++GO:0008150///biological_process","tetraspanin 3","[TSN3_HUMAN|Reviewed]RecName: Full=Tetraspanin-3; Short=Tspan-3; AltName: Full=Tetraspanin TM4-A; AltName: Full=Transmembrane 4 superfamily member 8;+++[H0YKJ9_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000452835};+++[H0YMH8_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000453613};+++[L8E893_HUMAN|Unreviewed]SubName: Full=Alternative protein TSPAN3 {ECO:0000313|EMBL:CCQ43334.1};"]
[100996259,"'FAM106B'",2.04,0,2.09,1.37666666666667,{"$nulls":7},"family with sequence similarity 106 member B","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[F106A_HUMAN|diamond]RecName: Full=Protein FAM106A;+++[F106C_HUMAN|diamond]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[100996274,"'LOC100996274'",0,1,0,0.333333333333333,"04657///IL-17 signaling pathway",{"$nulls":6},"uncharacterized LOC100996274","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MUC2_HUMAN|diamond]RecName: Full=Mucin-2; Short=MUC-2; AltName: Full=Intestinal mucin-2; Flags: Precursor;+++[MUC5A_HUMAN|diamond]RecName: Full=Mucin-5AC {ECO:0000305}; Short=MUC-5AC {ECO:0000305}; AltName: Full=Gastric mucin {ECO:0000303|PubMed:8948439}; AltName: Full=Lewis B blood group antigen {ECO:0000303|PubMed:14535999}; Short=LeB {ECO:0000303|PubMed:14535999}; AltName: Full=Major airway glycoprotein {ECO:0000303|PubMed:7513696}; AltName: Full=Mucin-5 subtype AC, tracheobronchial; AltName: Full=Tracheobronchial mucin {ECO:0000303|PubMed:2656675}; Short=TBM {ECO:0000303|PubMed:7513696}; Flags: Precursor;"]
[100996318,"'LOC100996318'",0,5,2,2.33333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006334///nucleosome assembly","uncharacterized LOC100996318","[H2B1_BOVIN|diamond]RecName: Full=Histone H2B type 1;+++[H2B1H_HUMAN|diamond]RecName: Full=Histone H2B type 1-H; AltName: Full=Histone H2B.j; Short=H2B/j;+++[H2B1O_HUMAN|diamond]RecName: Full=Histone H2B type 1-O; AltName: Full=Histone H2B.2; AltName: Full=Histone H2B.n; Short=H2B/n;+++[H2B2B_MOUSE|diamond]RecName: Full=Histone H2B type 2-B; AltName: Full=H2b 616;+++[H2B2F_HUMAN|diamond]RecName: Full=Histone H2B type 2-F;"]
[100996379,"'LOC100996379'",0,5.18,5.04,3.40666666666667,"04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal+++04137///Mitophagy - animal","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0032183///SUMO binding+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0007283///spermatogenesis+++GO:0006886///intracellular protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0016567///protein ubiquitination+++GO:0006974///cellular response to DNA damage stimulus","E3 ubiquitin-protein ligase HERC2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996414,"'100996414'",44.13,66.26,49.66,53.35,{"$nulls":8},"[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[100996485,"'C5orf66'",0,1,0,0.333333333333333,"05034///Alcoholism+++04140///Autophagy - animal+++04217///Necroptosis+++04137///Mitophagy - animal+++05322///Systemic lupus erythematosus","H00903///Congenital clubfoot",null,null,"GO:0070062///extracellular exosome+++GO:0000793///condensed chromosome+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0001739///sex chromatin+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005721///pericentric heterochromatin+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0000786///nucleosome+++GO:0000790///nuclear chromatin+++GO:0000228///nuclear chromosome","GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0031490///chromatin DNA binding+++GO:0019901///protein kinase binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0019899///enzyme binding+++GO:1990841///promoter-specific chromatin binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0000182///rDNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0035116///embryonic hindlimb morphogenesis+++GO:1902883///negative regulation of response to oxidative stress+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007549///dosage compensation+++GO:1902884///positive regulation of response to oxidative stress+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0006342///chromatin silencing+++GO:0001501///skeletal system development+++GO:0051216///cartilage development+++GO:1904815///negative regulation of protein localization to chromosome, telomeric region+++GO:0006355///regulation of transcription, DNA-templated+++GO:1902750///negative regulation of cell cycle G2/M phase transition+++GO:0071169///establishment of protein localization to chromatin+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0006351///transcription, DNA-templated+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:0019216///regulation of lipid metabolic process+++GO:0014707///branchiomeric skeletal muscle development+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0040029///regulation of gene expression, epigenetic+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0033128///negative regulation of histone phosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0006334///nucleosome assembly+++GO:0048625///myoblast fate commitment+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902882///regulation of response to oxidative stress+++GO:0021983///pituitary gland development+++GO:0045618///positive regulation of keratinocyte differentiation","chromosome 5 open reading frame 66","[CE066_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C5orf66;"]
[100996492,"'CTXND1'",6,1,2,3,null,"H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane+++GO:0016020///membrane",null,null,"cortexin domain containing 1","[CTXD1_HUMAN|Reviewed]RecName: Full=Cortexin domain-containing 1 {ECO:0000305};"]
[100996517,"'SEC22B3'",101.82,69.44,73.57,81.61,"04145///Phagosome+++04130///SNARE interactions in vesicular transport+++05134///Legionellosis",{"$nulls":3},"GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000139///Golgi membrane+++GO:0042470///melanosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0008021///synaptic vesicle+++GO:0030133///transport vesicle","GO:0000149///SNARE binding+++GO:0019905///syntaxin binding+++GO:0005484///SNAP receptor activity","GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:1902902///negative regulation of autophagosome assembly+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0045732///positive regulation of protein catabolic process+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent","SEC22 homolog B3","[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996598,"'LOC100996598'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005622///intracellular","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","uncharacterized LOC100996598","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996643,"'LOC100996643'",0,3.53,0,1.17666666666667,"00670///One carbon pool by folate+++04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005739///mitochondrion","GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0005524///ATP binding+++GO:0015267///channel activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008236///serine-type peptidase activity+++GO:0042803///protein homodimerization activity+++GO:0004180///carboxypeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity+++GO:0004329///formate-tetrahydrofolate ligase activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity","GO:0042135///neurotransmitter catabolic process+++GO:0006508///proteolysis+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0001843///neural tube closure+++GO:0006760///folic acid-containing compound metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0009113///purine nucleobase biosynthetic process+++GO:0046655///folic acid metabolic process+++GO:0015942///formate metabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0009257///10-formyltetrahydrofolate biosynthetic process","monofunctional C1-tetrahydrofolate synthase, mitochondrial-like","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[TR43B_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43B;+++[TRI43_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996693,"'LOC100996693'",11,5,6,7.33333333333333,{"$nulls":7},"CAVP-target protein-like","[A0A087WV53_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000479190};"]
[100996709,"'LOC100996709'",202.74,186.8,181.19,190.243333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore","GO:0005525///GTP binding+++GO:0008270///zinc ion binding+++GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0004181///metallocarboxypeptidase activity+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)","GO:0043984///histone H4-K16 acetylation+++GO:0015031///protein transport+++GO:0035610///protein side chain deglutamylation+++GO:0043981///histone H4-K5 acetylation+++GO:0016192///vesicle-mediated transport+++GO:0043982///histone H4-K8 acetylation","ADP-ribosylation factor-like protein 17","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};"]
[100996716,"'SEC22B2'",153.27,128.08,155.13,145.493333333333,"04145///Phagosome+++05134///Legionellosis+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030133///transport vesicle+++GO:0042470///melanosome+++GO:0030670///phagocytic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0031201///SNARE complex+++GO:0000139///Golgi membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005789///endoplasmic reticulum membrane+++GO:0005622///intracellular+++GO:0016021///integral component of membrane","GO:0005484///SNAP receptor activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0045732///positive regulation of protein catabolic process+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0015031///protein transport+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane","SEC22 homolog B2","[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996717,"'NOTCH2NLC'",348.89,359.57,334.04,347.5,"01522///Endocrine resistance+++05224///Breast cancer+++04320///Dorso-ventral axis formation+++05200///Pathways in cancer+++04919///Thyroid hormone signaling pathway+++04658///Th1 and Th2 cell differentiation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection","H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development+++GO:0045747///positive regulation of Notch signaling pathway","notch 2 N-terminal like C","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NC_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[100996720,"'LOC100996720'",151,139,127,139,{"$nulls":4},"GO:0005622///intracellular","GO:0003950///NAD+ ADP-ribosyltransferase activity",null,"uncharacterized LOC100996720","[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;"]
[100996741,"'100996741'",7,10,7,8,{"$nulls":8},"[F231A_HUMAN|diamond]RecName: Full=Putative protein FAM231AP {ECO:0000305};+++[F231B_HUMAN|diamond]RecName: Full=Putative protein FAM231BP;+++[F231C_HUMAN|diamond]RecName: Full=Protein FAM231C;+++[F231D_HUMAN|diamond]RecName: Full=Protein FAM231D;+++[F231L_HUMAN|diamond]RecName: Full=FAM231A/C-like protein LOC102723383;"]
[100996746,"'SPDYE11'",3,0,1,1.33333333333333,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E11","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE2_HUMAN|diamond]RecName: Full=Speedy protein E2;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPDE6_HUMAN|diamond]RecName: Full=Speedy protein E6;+++[SPE2B_HUMAN|diamond]RecName: Full=Speedy protein E2B;"]
[100996747,"'LOC100996747'",97.49,77.15,68.56,81.0666666666667,{"$nulls":4},"GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane+++GO:0022627///cytosolic small ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0003729///mRNA binding","GO:0002181///cytoplasmic translation+++GO:0033119///negative regulation of RNA splicing","40S ribosomal protein S26","[RS26_BOVIN|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_HUMAN|diamond]RecName: Full=40S ribosomal protein S26; AltName: Full=Small ribosomal subunit protein eS26 {ECO:0000303|PubMed:24524803};+++[RS26_MACFA|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_MOUSE|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_PIG|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_RAT|diamond]RecName: Full=40S ribosomal protein S26;"]
[100996758,"'NPY4R2'",3.77,2.35,1.85,2.65666666666667,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0001602///pancreatic polypeptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017046///peptide hormone binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007218///neuropeptide signaling pathway","neuropeptide Y receptor Y4-2","[NPY4R_HUMAN|Reviewed]RecName: Full=Neuropeptide Y receptor type 4; Short=NPY4-R; AltName: Full=Pancreatic polypeptide receptor 1; Short=PP1;"]
[100996763,"'NOTCH2NLB'",429.36,384.64,316.49,376.83,"05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005112///Notch binding+++GO:0005515///protein binding","GO:0045747///positive regulation of Notch signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development","notch 2 N-terminal like B","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[A0A0B4J2B3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 14 {ECO:0000313|Ensembl:ENSP00000472124};"]
[100996792,"'LOC100996792'",2.01,0,0,0.67,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0004708///MAP kinase kinase activity+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity","GO:0031098///stress-activated protein kinase signaling cascade+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006954///inflammatory response+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0000187///activation of MAPK activity+++GO:0042981///regulation of apoptotic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060048///cardiac muscle contraction+++GO:0023014///signal transduction by protein phosphorylation+++GO:0007165///signal transduction+++GO:0038066///p38MAPK cascade+++GO:0032147///activation of protein kinase activity+++GO:0007346///regulation of mitotic cell cycle+++GO:0043536///positive regulation of blood vessel endothelial cell migration","dual specificity mitogen-activated protein kinase kinase 3 pseudogene","[MP2K3_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000269|PubMed:8622669}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3; AltName: Full=Stress-activated protein kinase kinase 2; Short=SAPK kinase 2; Short=SAPKK-2; Short=SAPKK2;+++[MP2K3_MOUSE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000250|UniProtKB:P46734}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3;+++[MP2K6_BOVIN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6;+++[MP2K6_DANRE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAP kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAPKK 6 {ECO:0000250|UniProtKB:P52564}; EC=2.7.12.2; AltName: Full=Mitogen-activated protein kinase kinase 3 {ECO:0000303|PubMed:10995439}; Short=zMKK3 {ECO:0000312|EMBL:BAB11809.1};+++[MP2K6_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6; AltName: Full=Stress-activated protein kinase kinase 3; Short=SAPK kinase 3; Short=SAPKK-3; Short=SAPKK3;"]
[100996842,"'LOC100996842'",26,14,16,18.6666666666667,"04142///Lysosome",{"$nulls":3},"GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane",null,"GO:0043312///neutrophil degranulation+++GO:0071310///cellular response to organic substance","uncharacterized LOC100996842","[CD68_HUMAN|diamond]RecName: Full=Macrosialin; AltName: Full=Gp110; AltName: CD_antigen=CD68; Flags: Precursor;+++[CD68_MOUSE|diamond]RecName: Full=Macrosialin; AltName: CD_antigen=CD68; Flags: Precursor;+++[MPU1_CRIGR|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation; Short=SL15;+++[MPU1_HUMAN|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;+++[MPU1_MOUSE|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;"]
[100996911,"'LOC100996911'",0,5.45,0,1.81666666666667,{"$nulls":4},"GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0031258///lamellipodium membrane+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0043202///lysosomal lumen+++GO:0005576///extracellular region+++GO:0016324///apical plasma membrane+++GO:0005796///Golgi lumen+++GO:0062023///collagen-containing extracellular matrix","GO:0019901///protein kinase binding","GO:0035556///intracellular signal transduction+++GO:0000187///activation of MAPK activity+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0008283///cell proliferation+++GO:0048771///tissue remodeling+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030207///chondroitin sulfate catabolic process+++GO:0008347///glial cell migration+++GO:0001525///angiogenesis+++GO:0030208///dermatan sulfate biosynthetic process","putative ubiquitin-conjugating enzyme E2Q2-like protein","[A0A024R018_HUMAN|Unreviewed]SubName: Full=HCG1818167, isoform CRA_a {ECO:0000313|EMBL:EAW55850.1};"]
[100996939,"'PYURF'",369,325.5,328,340.833333333333,"00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis+++01100///Metabolic pathways","H01488///Hyperphosphatasia with mental retardation syndrome (HPMPS)+++H01489///Inherited glycosylphosphatidylinositol (GPI) deficiencies",null,"R05916///UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143","GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0009893///positive regulation of metabolic process+++GO:0006506///GPI anchor biosynthetic process","PIGY upstream reading frame","[PREY_HUMAN|Reviewed]RecName: Full=Protein preY, mitochondrial; AltName: Full=PIGY upstream reading frame protein; Flags: Precursor;"]
[101,"'ADAM8'",498,638,528,554.666666666667,{"$nulls":4},"GO:0070821///tertiary granule membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0042581///specific granule+++GO:0032127///dense core granule membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0032010///phagolysosome+++GO:0016020///membrane+++GO:0070820///tertiary granule+++GO:0071065///alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex+++GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0002102///podosome+++GO:0035579///specific granule membrane+++GO:0071133///alpha9-beta1 integrin-ADAM8 complex","GO:0008237///metallopeptidase activity+++GO:0050839///cell adhesion molecule binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0043621///protein self-association","GO:0071456///cellular response to hypoxia+++GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:2000418///positive regulation of eosinophil migration+++GO:0043406///positive regulation of MAP kinase activity+++GO:0050714///positive regulation of protein secretion+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0045780///positive regulation of bone resorption+++GO:2000415///positive regulation of fibronectin-dependent thymocyte migration+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0001525///angiogenesis+++GO:0045089///positive regulation of innate immune response+++GO:0022617///extracellular matrix disassembly+++GO:0002693///positive regulation of cellular extravasation+++GO:2000406///positive regulation of T cell migration+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:2000309///positive regulation of tumor necrosis factor (ligand) superfamily member 11 production+++GO:0010954///positive regulation of protein processing+++GO:0043312///neutrophil degranulation+++GO:0050729///positive regulation of inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0098609///cell-cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0048247///lymphocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0022407///regulation of cell-cell adhesion","ADAM metallopeptidase domain 8","[ADAM8_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 8; Short=ADAM 8; EC=3.4.24.-; AltName: Full=Cell surface antigen MS2; AltName: CD_antigen=CD156a; Flags: Precursor;+++[H0YKZ1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000452994};+++[H0YMT6_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000453735}; Flags: Fragment;+++[Q14C66_HUMAN|Unreviewed]SubName: Full=ADAM8 protein {ECO:0000313|EMBL:AAI15405.1}; SubName: Full=cDNA, FLJ93272, highly similar to Homo sapiens a disintegrin and metalloproteinase domain 8 (ADAM8),mRNA {ECO:0000313|EMBL:BAG35688.1};"]
[1010,"'CDH12'",33,41,39,37.6666666666667,{"$nulls":4},"GO:0016342///catenin complex+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding","GO:0034332///adherens junction organization+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","cadherin 12","[CAD12_HUMAN|Reviewed]RecName: Full=Cadherin-12; AltName: Full=Brain cadherin; Short=BR-cadherin; AltName: Full=Neural type cadherin 2; Short=N-cadherin 2; Flags: Precursor;"]
[10100,"'TSPAN2'",132,91,169,130.666666666667,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0007166///cell surface receptor signaling pathway+++GO:0048709///oligodendrocyte differentiation+++GO:0014005///microglia development+++GO:0014002///astrocyte development+++GO:0006954///inflammatory response+++GO:0042552///myelination+++GO:0061564///axon development+++GO:0007420///brain development","tetraspanin 2","[TSN2_HUMAN|Reviewed]RecName: Full=Tetraspanin-2; Short=Tspan-2; AltName: Full=Tetraspan NET-3;+++[B1AKP1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[B1AKP2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[B2RD31_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};"]
[10101,"'NUBP2'",849,858,825,844,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0005929///cilium+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0000166///nucleotide binding+++GO:0051536///iron-sulfur cluster binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0051642///centrosome localization+++GO:0001558///regulation of cell growth+++GO:0030030///cell projection organization+++GO:0006879///cellular iron ion homeostasis+++GO:0010826///negative regulation of centrosome duplication+++GO:0016226///iron-sulfur cluster assembly+++GO:0072697///protein localization to cell cortex","nucleotide binding protein 2","[NUBP2_HUMAN|Reviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000255|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000255|HAMAP-Rule:MF_03039};+++[B2RDN3_HUMAN|Unreviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000256|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000256|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000256|HAMAP-Rule:MF_03039};+++[B7Z6P0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000460079}; SubName: Full=Nucleotide binding protein 2 (MinD homolog, E. coli), isoform CRA_d {ECO:0000313|EMBL:EAW85616.1}; SubName: Full=cDNA FLJ57200, highly similar to Nucleotide-binding protein 2 {ECO:0000313|EMBL:BAH13326.1};+++[H3BMW1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454576}; Flags: Fragment;+++[H3BNF0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454815};+++[H3BNS4_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454982}; Flags: Fragment;+++[H3BQE5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455739}; Flags: Fragment;+++[H3BQR2_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455896};+++[H3BRE1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456199}; Flags: Fragment;+++[H3BRK5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456284};+++[I3L3A0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000460288}; Flags: Fragment;+++[I3L518_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461723}; Flags: Fragment;+++[I3L531_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461746}; Flags: Fragment;+++[Q2YS46_HUMAN|Unreviewed]SubName: Full=C447E6.1 (Nucleotide binding protein 1 (E.coli MinD like) ) {ECO:0000313|EMBL:CAC36077.1}; Flags: Fragment;"]
[10102,"'TSFM'",207,215,204,208.666666666667,null,"H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0003746///translation elongation factor activity+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0006414///translational elongation+++GO:0070129///regulation of mitochondrial translation+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","Ts translation elongation factor, mitochondrial","[EFTS_HUMAN|Reviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135}; Flags: Precursor;+++[B4DHY8_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[C9JG32_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000390679}; Flags: Fragment;+++[C9JT21_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000389162}; Flags: Fragment;+++[E5KS95_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VPA7_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VS27_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8WCK2_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000406339};"]
[10103,"'TSPAN1'",10,5,5,6.66666666666667,"04213///Longevity regulating pathway - multiple species+++04071///Sphingolipid signaling pathway+++04218///Cellular senescence+++05166///HTLV-I infection+++04360///Axon guidance+++05161///Hepatitis B+++05212///Pancreatic cancer+++05164///Influenza A+++04666///Fc gamma R-mediated phagocytosis+++05162///Measles+++01521///EGFR tyrosine kinase inhibitor resistance+++04211///Longevity regulating pathway+++05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++04931///Insulin resistance+++05225///Hepatocellular carcinoma+++05146///Amoebiasis+++05165///Human papillomavirus infection+++04910///Insulin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04150///mTOR signaling pathway+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++05226///Gastric cancer+++05221///Acute myeloid leukemia+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++04722///Neurotrophin signaling pathway+++05210///Colorectal cancer+++04750///Inflammatory mediator regulation of TRP channels+++04072///Phospholipase D signaling pathway+++04917///Prolactin signaling pathway+++05213///Endometrial cancer+++05220///Chronic myeloid leukemia+++04152///AMPK signaling pathway+++04926///Relaxin signaling pathway+++05223///Non-small cell lung cancer+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04210///Apoptosis+++04630///Jak-STAT signaling pathway+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++05163///Human cytomegalovirus infection+++04810///Regulation of actin cytoskeleton+++04380///Osteoclast differentiation+++04012///ErbB signaling pathway+++04611///Platelet activation+++01524///Platinum drug resistance+++05160///Hepatitis C+++04014///Ras signaling pathway+++04625///C-type lectin receptor signaling pathway+++05215///Prostate cancer+++05222///Small cell lung cancer+++04070///Phosphatidylinositol signaling system+++05224///Breast cancer+++04510///Focal adhesion+++05231///Choline metabolism in cancer+++05203///Viral carcinogenesis+++04140///Autophagy - animal+++05230///Central carbon metabolism in cancer+++04930///Type II diabetes mellitus+++01522///Endocrine resistance+++04670///Leukocyte transendothelial migration+++04919///Thyroid hormone signaling pathway+++05218///Melanoma+++05142///Chagas disease (American trypanosomiasis)+++05214///Glioma+++04550///Signaling pathways regulating pluripotency of stem cells+++04370///VEGF signaling pathway+++04973///Carbohydrate digestion and absorption+++04062///Chemokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04650///Natural killer cell mediated cytotoxicity+++04620///Toll-like receptor signaling pathway+++04068///FoxO signaling pathway+++04915///Estrogen signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04024///cAMP signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++05169///Epstein-Barr virus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04725///Cholinergic synapse+++04960///Aldosterone-regulated sodium reabsorption","H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01370///SHORT syndrome","M00676///PI3K-Akt signaling","R03362///ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate+++R04545///ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate+++R05795///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate","GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane+++GO:0031982///vesicle+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0045807///positive regulation of endocytosis+++GO:0007166///cell surface receptor signaling pathway+++GO:0050821///protein stabilization+++GO:0008283///cell proliferation+++GO:0016477///cell migration","tetraspanin 1","[TSN1_HUMAN|Reviewed]RecName: Full=Tetraspanin-1; Short=Tspan-1; AltName: Full=Tetraspan NET-1; AltName: Full=Tetraspanin TM4-C;"]
[10105,"'PPIF'",978,1025,959,987.333333333333,"04020///Calcium signaling pathway+++05016///Huntington's disease+++05145///Toxoplasmosis+++05012///Parkinson's disease+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005753///mitochondrial proton-transporting ATP synthase complex","GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0042277///peptide binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding","GO:0012501///programmed cell death+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0010939///regulation of necrotic cell death+++GO:0002931///response to ischemia+++GO:0043066///negative regulation of apoptotic process+++GO:0010849///regulation of proton-transporting ATPase activity, rotational mechanism+++GO:0006457///protein folding+++GO:0008637///apoptotic mitochondrial changes+++GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0032780///negative regulation of ATPase activity+++GO:2000276///negative regulation of oxidative phosphorylation uncoupler activity+++GO:0071243///cellular response to arsenic-containing substance+++GO:0006979///response to oxidative stress+++GO:1902686///mitochondrial outer membrane permeabilization involved in programmed cell death+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0071277///cellular response to calcium ion+++GO:0070301///cellular response to hydrogen peroxide+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0070266///necroptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria","peptidylprolyl isomerase F","[PPIF_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase F, mitochondrial; Short=PPIase F; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Cyclophilin D; Short=CyP-D; Short=CypD; AltName: Full=Cyclophilin F; AltName: Full=Mitochondrial cyclophilin; Short=CyP-M; AltName: Full=Rotamase F; Flags: Precursor;+++[A0A024QZS4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[H0Y548_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[R4GN99_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[101059906,"'LOC101059906'",16,22,14,17.3333333333333,"01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,null,"R07376///L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0098978///glutamatergic synapse+++GO:0000139///Golgi membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol","GO:0019003///GDP binding+++GO:0016740///transferase activity+++GO:0003924///GTPase activity+++GO:0003882///CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0005525///GTP binding+++GO:0008022///protein C-terminus binding","GO:0071480///cellular response to gamma radiation+++GO:0090303///positive regulation of wound healing+++GO:0048013///ephrin receptor signaling pathway+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007265///Ras protein signal transduction+++GO:0051291///protein heterooligomerization+++GO:0034260///negative regulation of GTPase activity+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0042088///T-helper 1 type immune response+++GO:0043406///positive regulation of MAP kinase activity+++GO:0006897///endocytosis+++GO:0043547///positive regulation of GTPase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0010629///negative regulation of gene expression+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:2000630///positive regulation of miRNA metabolic process+++GO:0046330///positive regulation of JNK cascade+++GO:0008283///cell proliferation+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0006935///chemotaxis+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1900029///positive regulation of ruffle assembly+++GO:0007165///signal transduction+++GO:0000165///MAPK cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0090398///cellular senescence+++GO:0035900///response to isolation stress+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0010863///positive regulation of phospholipase C activity+++GO:0050852///T cell receptor signaling pathway+++GO:0042832///defense response to protozoan+++GO:0045740///positive regulation of DNA replication+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0007050///cell cycle arrest+++GO:0001934///positive regulation of protein phosphorylation+++GO:0043524///negative regulation of neuron apoptotic process","collagen alpha-2(IV) chain-like","[CO3A1_CHICK|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor; Fragments;+++[CO3A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(IV) chain; Contains: RecName: Full=Arresten; Flags: Precursor;+++[CO7A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(VII) chain; AltName: Full=Long-chain collagen; Short=LC collagen; Flags: Precursor;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[LRC56_HUMAN|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_MOUSE|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_RAT|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[PTSS2_CHICK|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_CRIGR|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_HUMAN|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_MOUSE|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_RAT|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[RASH_CHICK|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_HUMAN|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Ha-Ras; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_MOUSE|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_RAT|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASK_KRYMA|diamond]RecName: Full=GTPase KRas; AltName: Full=Ki-Ras; Short=K-ras; Flags: Precursor;+++[RASK_MONDO|diamond]RecName: Full=GTPase KRas; AltName: Full=K-Ras 2; AltName: Full=Ki-Ras; AltName: Full=c-K-ras; AltName: Full=c-Ki-ras; Contains: RecName: Full=GTPase KRas, N-terminally processed; Flags: Precursor;+++[RINI_HUMAN|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Placental ribonuclease inhibitor; Short=Placental RNase inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1; Short=RAI;+++[RINI_PANTR|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_PIG|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_RAT|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[101059918,"'GOLGA8R'",22.35,23.58,23.29,23.0733333333333,"04530///Tight junction",{"$nulls":3},"GO:0005794///Golgi apparatus",null,null,"golgin A8 family member R","[GOG8R_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 8R;"]
[101059938,"'NPIPA7'",914.53,989.8,1030.14,978.156666666667,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"nuclear pore complex interacting protein family member A7","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0Y2X3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A7 {ECO:0000313|Ensembl:ENSP00000343256}; Flags: Fragment;"]
[101059953,"'NPIPA8'",203.61,248.59,180.22,210.806666666667,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"nuclear pore complex interacting protein family member A8","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0YFN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A8 {ECO:0000313|Ensembl:ENSP00000439498}; Flags: Fragment;"]
[10106,"'CTDSP2'",1655,1748,1574,1659,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0016791///phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0016311///dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle","CTD small phosphatase 2","[CTDS2_HUMAN|Reviewed]RecName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; EC=3.1.3.16; AltName: Full=Nuclear LIM interactor-interacting factor 2; Short=NLI-interacting factor 2; AltName: Full=Protein OS-4; AltName: Full=Small C-terminal domain phosphatase 2; AltName: Full=Small CTD phosphatase 2; Short=SCP2;+++[A0A024RB65_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_b {ECO:0000313|EMBL:EAW97086.1};+++[A0A024RBA6_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_c {ECO:0000313|EMBL:EAW97089.1};+++[F8VYL0_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448951};+++[F8W184_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000446705};+++[F8W1I1_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000447046};+++[H0YI12_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448299}; Flags: Fragment;+++[H0YI29_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448386}; Flags: Fragment;"]
[101060017,"'LOC101060017'",4,0,0,1.33333333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0032587///ruffle membrane+++GO:0005829///cytosol","GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0004672///protein kinase activity+++GO:0071889///14-3-3 protein binding+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0000165///MAPK cascade+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0043405///regulation of MAP kinase activity","translation initiation factor IF-2-like","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[KSR2_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 2; Short=hKSR2; EC=2.7.11.1;+++[KSR2_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 2; EC=2.7.11.1;"]
[101060022,"'LOC101060022'",431.03,641.58,499.84,524.15,{"$nulls":7},"nascent polypeptide-associated complex subunit alpha, muscle-specific form-like","[PRR36_HUMAN|diamond]RecName: Full=Proline-rich protein 36 {ECO:0000312|HGNC:HGNC:26172};+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[101060179,"'LOC101060179'",72,72,83,75.6666666666667,{"$nulls":7},"uncharacterized LOC101060179","[A0A2J8LHJ5_PANTR|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNI46744.1}; Flags: Fragment;+++[A0A2J8WFF8_PONAB|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNJ68516.1}; Flags: Fragment;+++[A0A2R8MD89_CALJA|diamond]SubName: Full=PR/SET domain 11 {ECO:0000313|Ensembl:ENSCJAP00000057788};+++[H3BSZ2_HUMAN|diamond]SubName: Full=PR domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000456942}; Flags: Fragment;+++[Q8N1K6_HUMAN|diamond]SubName: Full=cDNA FLJ40559 fis, clone THYMU2002910 {ECO:0000313|EMBL:BAC05192.1};"]
[101060200,"'ZNF891'",7,11,7,8.33333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 891","[ZN891_HUMAN|Reviewed]RecName: Full=Zinc finger protein 891;"]
[101060226,"'NBPF19'",1394.75,1548.27,1379.65,1440.89,"05224///Breast cancer+++01522///Endocrine resistance+++04137///Mitophagy - animal+++04330///Notch signaling pathway+++05200///Pathways in cancer+++04140///Autophagy - animal+++04320///Dorso-ventral axis formation+++04658///Th1 and Th2 cell differentiation+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection+++04919///Thyroid hormone signaling pathway","H00551///Alagille syndrome+++H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","NBPF member 19","[NBPFJ_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};+++[A0A075B6G5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000358229};+++[A0A087X230_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484655};+++[A0A087X288_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484787};"]
[101060254,"'LOC101060254'",41,66.06,55.03,54.03,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0030016///myofibril","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization+++GO:1903358///regulation of Golgi organization+++GO:0034622///cellular protein-containing complex assembly","myomegalin-like","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_MOUSE|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[CK5P2_RAT|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFK_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 20;+++[NBPFP_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 26;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101060321,"'TBC1D3G'",40.29,60.54,64.74,55.19,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","TBC1 domain family member 3G","[TBC3C_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3C;+++[TBC3G_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3G;"]
[101060341,"'LOC101060341'",339.82,569.53,437.48,448.943333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC101060341","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101060351,"'TBC1D3K'",8.28,19.47,12.74,13.4966666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","TBC1 domain family member 3K","[TBC3K_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3K {ECO:0000312|HGNC:HGNC:51245};+++[A0A0G2JPY0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3K {ECO:0000313|Ensembl:ENSP00000484542};"]
[101060376,"'TBC1D3L'",434.22,643.16,507.33,528.236666666667,{"$nulls":4},"GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0005622///intracellular","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0031338///regulation of vesicle fusion+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3L","[TBC3L_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3L {ECO:0000312|HGNC:HGNC:51246};+++[A0A0G2JP35_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3L {ECO:0000313|Ensembl:ENSP00000482811};+++[B3KTC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38066 fis, clone CTONG2015330, highly similar to TBC1 domain family member 3 {ECO:0000313|EMBL:BAG53037.1};"]
[101060389,"'TBC1D3D'",19.65,24.23,55.07,32.9833333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:1902017///regulation of cilium assembly+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3D","[TBC3D_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3D {ECO:0000312|HGNC:HGNC:28944};"]
[101060684,"'NBPF26'",461.37,615.12,528.65,535.046666666667,"04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++04140///Autophagy - animal+++05200///Pathways in cancer+++04137///Mitophagy - animal+++05165///Human papillomavirus infection+++04320///Dorso-ventral axis formation+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++01522///Endocrine resistance+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","NBPF member 26","[NBPFP_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 26;+++[A0A075B7F9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000476257};+++[A0A087WTG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000477847};+++[A0A087WU30_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000478334};+++[A0A087WVV8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000479721};+++[A0A087WWQ1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000480416};+++[A0A087WY62_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000481542};+++[A0A087WZB6_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482516};+++[A0A087WZS8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482859};+++[A0A096LNW5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000485259};"]
[10109,"'ARPC2'",5053,4352,4412,4605.66666666667,"05132///Salmonella infection+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0005925///focal adhesion+++GO:0036195///muscle cell projection membrane+++GO:0035861///site of double-strand break+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031252///cell leading edge+++GO:0030027///lamellipodium+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0045202///synapse","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0070358///actin polymerization-dependent cell motility+++GO:0048013///ephrin receptor signaling pathway+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030041///actin filament polymerization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:0010592///positive regulation of lamellipodium assembly","actin related protein 2/3 complex subunit 2","[ARPC2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 2; AltName: Full=Arp2/3 complex 34 kDa subunit; Short=p34-ARC;+++[A0A024R408_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[C9JTV5_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[G5E9J0_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[G5E9S7_HUMAN|Unreviewed]SubName: Full=Actin related protein 2/3 complex, subunit 2, 34kDa, isoform CRA_e {ECO:0000313|EMBL:EAW70596.1}; SubName: Full=Actin-related protein 2/3 complex subunit 2 {ECO:0000313|Ensembl:ENSP00000412632};+++[H7C3F9_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[Q53R19_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};"]
[10110,"'SGK2'",7,4,6,5.66666666666667,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular","GO:0005524///ATP binding+++GO:0017081///chloride channel regulator activity+++GO:0005246///calcium channel regulator activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0015459///potassium channel regulator activity+++GO:0017080///sodium channel regulator activity","GO:0018105///peptidyl-serine phosphorylation+++GO:0034220///ion transmembrane transport+++GO:0001558///regulation of cell growth+++GO:0032411///positive regulation of transporter activity+++GO:0006468///protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0006979///response to oxidative stress+++GO:0042127///regulation of cell proliferation","SGK2, serine/threonine kinase 2","[SGK2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk2; EC=2.7.11.1; AltName: Full=Serum/glucocorticoid-regulated kinase 2;"]
[10111,"'RAD50'",995,1113,983,1030.33333333333,"03450///Non-homologous end-joining+++04218///Cellular senescence+++03440///Homologous recombination","H01344///Nijmegen syndrome","M00292///MRX complex+++M00291///MRN complex+++M00295///BRCA1-associated genome surveillance complex (BASC)",null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000790///nuclear chromatin+++GO:0030870///Mre11 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0008408///3'-5' exonuclease activity+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003691///double-stranded telomeric DNA binding+++GO:0004017///adenylate kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding+++GO:0043047///single-stranded telomeric DNA binding","GO:0016032///viral process+++GO:0033674///positive regulation of kinase activity+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0032206///positive regulation of telomere maintenance+++GO:0000019///regulation of mitotic recombination+++GO:0016233///telomere capping+++GO:0000723///telomere maintenance+++GO:0000722///telomere maintenance via recombination+++GO:0000729///DNA double-strand break processing+++GO:0007004///telomere maintenance via telomerase+++GO:0031860///telomeric 3' overhang formation+++GO:0032508///DNA duplex unwinding+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0000724///double-strand break repair via homologous recombination+++GO:1904354///negative regulation of telomere capping+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0006260///DNA replication+++GO:0070192///chromosome organization involved in meiotic cell cycle","RAD50 double strand break repair protein","[RAD50_HUMAN|Reviewed]RecName: Full=DNA repair protein RAD50; Short=hRAD50; EC=3.6.-.-;+++[A5D6Y3_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI40006.1}; Flags: Fragment;+++[C9JNH8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000389515}; Flags: Fragment;+++[E7EN38_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000400049}; Flags: Fragment;+++[E7ESD9_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000390971};+++[E9PM98_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000431225};+++[H7C0P8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396100}; Flags: Fragment;+++[H7C0V2_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396860}; Flags: Fragment;+++[Q32P42_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI08283.1}; Flags: Fragment;"]
[10112,"'KIF20A'",4,5,6,5,{"$nulls":4},"GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005819///spindle+++GO:0045171///intercellular bridge+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005871///kinesin complex","GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0003777///microtubule motor activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0007018///microtubule-based movement+++GO:0032465///regulation of cytokinesis+++GO:0061952///midbody abscission+++GO:0000281///mitotic cytokinesis+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0001578///microtubule bundle formation","kinesin family member 20A","[KI20A_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF20A; AltName: Full=GG10_2; AltName: Full=Mitotic kinesin-like protein 2; Short=MKlp2; AltName: Full=Rab6-interacting kinesin-like protein; AltName: Full=Rabkinesin-6;+++[D6R9E4_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000422928}; Flags: Fragment;+++[D6RBN1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000424056}; Flags: Fragment;+++[H0YAC9_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000426704}; Flags: Fragment;"]
[10113,"'PREB'",1070,1143,1037,1083.33333333333,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005090///Sar guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0051020///GTPase binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0048208///COPII vesicle coating+++GO:0003400///regulation of COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0050790///regulation of catalytic activity+++GO:0009306///protein secretion+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0016192///vesicle-mediated transport","prolactin regulatory element binding","[PREB_HUMAN|Reviewed]RecName: Full=Prolactin regulatory element-binding protein; AltName: Full=Mammalian guanine nucleotide exchange factor mSec12;+++[A0A0F7RPZ8_HUMAN|Unreviewed]SubName: Full=Prometheus B {ECO:0000313|EMBL:CCP37866.1};+++[B5MC98_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000384032};+++[F8WCS5_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000416103};+++[H7BZX0_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000391894}; Flags: Fragment;+++[H7C0W3_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000397036}; Flags: Fragment;+++[H7C2N7_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000407036}; Flags: Fragment;+++[Q05DB2_HUMAN|Unreviewed]SubName: Full=PREB protein {ECO:0000313|EMBL:AAH16906.1}; SubName: Full=Prolactin regulatory element binding, isoform CRA_d {ECO:0000313|EMBL:EAX00629.1};"]
[10114,"'HIPK3'",1145,1131,1084,1120,"04218///Cellular senescence",{"$nulls":3},"GO:0005829///cytosol+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0018107///peptidyl-threonine phosphorylation+++GO:0009299///mRNA transcription+++GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation","homeodomain interacting protein kinase 3","[HIPK3_HUMAN|Reviewed]RecName: Full=Homeodomain-interacting protein kinase 3; EC=2.7.11.1; AltName: Full=Androgen receptor-interacting nuclear protein kinase; Short=ANPK; AltName: Full=Fas-interacting serine/threonine-protein kinase; Short=FIST; AltName: Full=Homolog of protein kinase YAK1;+++[A8KAE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75520 {ECO:0000313|EMBL:BAF85698.1};+++[E9PKD7_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 3 {ECO:0000313|Ensembl:ENSP00000433594}; Flags: Fragment;"]
[10116,"'FEM1B'",453,460,460,457.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005123///death receptor binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:2000001///regulation of DNA damage checkpoint+++GO:0016567///protein ubiquitination+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0002070///epithelial cell maturation+++GO:0043687///post-translational protein modification+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0006915///apoptotic process","fem-1 homolog B","[FEM1B_HUMAN|Reviewed]RecName: Full=Protein fem-1 homolog B; Short=FEM1b; AltName: Full=FEM1-beta; AltName: Full=Fem-1-like death receptor-binding protein alpha; AltName: Full=Fem-1-like in apoptotic pathway protein alpha; Short=F1A-alpha;+++[H3BT12_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000456968}; Flags: Fragment;+++[H3BTV3_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000457342}; Flags: Fragment;"]
[1012,"'CDH13'",616,663,501,593.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016342///catenin complex+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0009986///cell surface+++GO:0048471///perinuclear region of cytoplasm+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0098982///GABA-ergic synapse+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0055100///adiponectin binding+++GO:0071813///lipoprotein particle binding+++GO:0008092///cytoskeletal protein binding+++GO:0045296///cadherin binding+++GO:0030169///low-density lipoprotein particle binding","GO:0010033///response to organic substance+++GO:0007266///Rho protein signal transduction+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0034332///adherens junction organization+++GO:0030335///positive regulation of cell migration+++GO:0043542///endothelial cell migration+++GO:0043616///keratinocyte proliferation+++GO:0016601///Rac protein signal transduction+++GO:0050927///positive regulation of positive chemotaxis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0007043///cell-cell junction assembly+++GO:0030032///lamellipodium assembly+++GO:0030100///regulation of endocytosis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0002040///sprouting angiogenesis+++GO:0007155///cell adhesion+++GO:0000278///mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051668///localization within membrane","cadherin 13","[CAD13_HUMAN|Reviewed]RecName: Full=Cadherin-13; AltName: Full=Heart cadherin; Short=H-cadherin; AltName: Full=P105; AltName: Full=Truncated cadherin; Short=T-cad; Short=T-cadherin; Flags: Precursor;+++[B7Z3H7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50547, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH12213.1};+++[B7Z9B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52398, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH14247.1};+++[F5H7W7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000442225};+++[H3BQH4_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000455781};+++[H3BRL7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000456297};+++[H3BTF2_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457149};+++[H3BV21_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457914};"]
[10120,"'ACTR1B'",748,780,809,779,{"$nulls":4},"GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0034774///secretory granule lumen+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0005869///dynactin complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0015630///microtubule cytoskeleton+++GO:0005856///cytoskeleton","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","ARP1 actin related protein 1 homolog B","[ACTY_HUMAN|Reviewed]RecName: Full=Beta-centractin; AltName: Full=Actin-related protein 1B; Short=ARP1B;"]
[10121,"'ACTR1A'",3135,2773,2832,2913.33333333333,{"$nulls":4},"GO:0005869///dynactin complex+++GO:0043209///myelin sheath+++GO:0005829///cytosol+++GO:0099738///cell cortex region+++GO:0030137///COPI-coated vesicle+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0002177///manchette+++GO:0015630///microtubule cytoskeleton+++GO:0005814///centriole+++GO:0070062///extracellular exosome+++GO:0005875///microtubule associated complex+++GO:0005815///microtubule organizing center+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0016192///vesicle-mediated transport+++GO:0007283///spermatogenesis+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport","ARP1 actin related protein 1 homolog A","[ACTZ_HUMAN|Reviewed]RecName: Full=Alpha-centractin; Short=Centractin; AltName: Full=ARP1; AltName: Full=Actin-RPV; AltName: Full=Centrosome-associated actin homolog;+++[A0A1B0GVS3_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000490634};+++[R4GMT0_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000473334};"]
[10123,"'ARL4C'",788,705,799,764,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding+++GO:0005525///GTP binding","GO:0032456///endocytic recycling+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","ADP ribosylation factor like GTPase 4C","[ARL4C_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4C; AltName: Full=ADP-ribosylation factor-like protein 7; AltName: Full=ADP-ribosylation factor-like protein LAK;+++[A0A024R4C5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4C, isoform CRA_a {ECO:0000313|EMBL:EAW71074.1};"]
[10124,"'ARL4A'",429.98,357,353.95,380.31,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","ADP ribosylation factor like GTPase 4A","[ARL4A_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4A;+++[A0A024R9Z2_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4A, isoform CRA_a {ECO:0000313|EMBL:EAW93652.1};+++[C9J7Q9_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 4A {ECO:0000313|Ensembl:ENSP00000397651}; Flags: Fragment;"]
[10125,"'RASGRP1'",110,105,104,106.333333333333,"05200///Pathways in cancer+++04660///T cell receptor signaling pathway+++04611///Platelet activation+++04014///Ras signaling pathway+++04010///MAPK signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0042629///mast cell granule+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0019992///diacylglycerol binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005096///GTPase activator activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031210///phosphatidylcholine binding+++GO:0042803///protein homodimerization activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1900744///regulation of p38MAPK cascade+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007264///small GTPase mediated signal transduction+++GO:1902715///positive regulation of interferon-gamma secretion+++GO:0090630///activation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0007165///signal transduction+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001816///cytokine production+++GO:0043303///mast cell degranulation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0047496///vesicle transport along microtubule+++GO:0043087///regulation of GTPase activity+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0007265///Ras protein signal transduction+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0000165///MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0032252///secretory granule localization+++GO:1900274///regulation of phospholipase C activity+++GO:0030154///cell differentiation+++GO:0032816///positive regulation of natural killer cell activation","RAS guanyl releasing protein 1","[GRP1_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 1; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor II; Short=CalDAG-GEFII; AltName: Full=Ras guanyl-releasing protein;+++[B2RA89_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94771, highly similar to Homo sapiens RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), mRNA {ECO:0000313|EMBL:BAG36786.1};+++[F5H514_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000444762};+++[H0YKM0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452859};+++[H0YKP8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452892}; Flags: Fragment;+++[H0YMF3_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453583}; Flags: Fragment;+++[H0YMT0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453729}; Flags: Fragment;+++[H0YN83_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453905}; Flags: Fragment;+++[H0YNG8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454005}; Flags: Fragment;+++[H0YNK9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454053}; Flags: Fragment;"]
[10126,"'DNAL4'",273,255,248,258.666666666667,"05016///Huntington's disease",{"$nulls":3},"GO:0005874///microtubule+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0030286///dynein complex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005929///cilium","GO:0051959///dynein light intermediate chain binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0005515///protein binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0045505///dynein intermediate chain binding","GO:0007018///microtubule-based movement+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed+++GO:0007017///microtubule-based process","dynein axonemal light chain 4","[DNAL4_HUMAN|Reviewed]RecName: Full=Dynein light chain 4, axonemal;+++[B0QXZ5_HUMAN|Unreviewed]RecName: Full=Dynein light chain {ECO:0000256|RuleBase:RU365010};"]
[10127,"'ZNF263'",456,435,404,431.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger protein 263","[ZN263_HUMAN|Reviewed]RecName: Full=Zinc finger protein 263; AltName: Full=Zinc finger protein FPM315; AltName: Full=Zinc finger protein with KRAB and SCAN domains 12;+++[B4DI05_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57935, highly similar to Zinc finger protein 263 {ECO:0000313|EMBL:BAG58317.1};+++[D3DUC1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263, isoform CRA_a {ECO:0000313|EMBL:EAW85380.1};+++[I3L0N0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000458214}; Flags: Fragment;+++[I3L2X3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000459998};+++[I3L393_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000460278};+++[I3L4C4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461146}; Flags: Fragment;+++[I3L538_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461755}; Flags: Fragment;+++[I3NI39_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461861}; Flags: Fragment;"]
[10128,"'LRPPRC'",1504,1451,1384,1446.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01354///Leigh syndrome+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0000794///condensed nuclear chromosome+++GO:1990904///ribonucleoprotein complex+++GO:0005874///microtubule+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005640///nuclear outer membrane+++GO:0005634///nucleus+++GO:0042645///mitochondrial nucleoid+++GO:0005637///nuclear inner membrane+++GO:0005856///cytoskeleton","GO:0008017///microtubule binding+++GO:0048487///beta-tubulin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0051015///actin filament binding+++GO:0003697///single-stranded DNA binding","GO:0070129///regulation of mitochondrial translation+++GO:0051028///mRNA transport+++GO:0000961///negative regulation of mitochondrial RNA catabolic process+++GO:0047497///mitochondrion transport along microtubule","leucine rich pentatricopeptide repeat containing","[LPPRC_HUMAN|Reviewed]RecName: Full=Leucine-rich PPR motif-containing protein, mitochondrial; AltName: Full=130 kDa leucine-rich protein; Short=LRP 130; AltName: Full=GP130; Flags: Precursor;+++[A0A0C4DG06_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386234};+++[B8ZZ38_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386562};+++[C9JCA9_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000403637}; Flags: Fragment;+++[E5KNY5_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR-motif containing {ECO:0000313|EMBL:EAX00284.1}; SubName: Full=Mitochondrial leucine-rich PPR motif-containing protein {ECO:0000313|EMBL:ADP90894.1};+++[H7C3W8_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000414207}; Flags: Fragment;"]
[10129,"'FRY'",214,234,241,229.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0004857///enzyme inhibitor activity","GO:0000902///cell morphogenesis+++GO:0043086///negative regulation of catalytic activity+++GO:0031175///neuron projection development+++GO:1904428///negative regulation of tubulin deacetylation","FRY microtubule binding protein","[FRY_HUMAN|Reviewed]RecName: Full=Protein furry homolog;+++[A0A024RDQ1_HUMAN|Unreviewed]SubName: Full=Furry homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAX08493.1};+++[A0A0C4DFX2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000369600};+++[A0A286YFA9_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000493189};+++[A0A2R8Y5V8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494761};+++[A0A2R8Y7Y8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000496501}; Flags: Fragment;+++[A0A2R8YCY2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494080};+++[B1ALA1_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000398010}; Flags: Fragment;+++[H0YE00_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000434694}; Flags: Fragment;+++[L8EB55_HUMAN|Unreviewed]SubName: Full=Alternative protein FRY {ECO:0000313|EMBL:CCQ43703.1};+++[Q96KW3_HUMAN|Unreviewed]SubName: Full=214K23.2.1 (Novel protein, isoform 1) {ECO:0000313|EMBL:CAC94765.1}; Flags: Fragment;+++[Q96KW4_HUMAN|Unreviewed]SubName: Full=214K23.2.2 (Novel protein, isoform 2) {ECO:0000313|EMBL:CAC94764.1}; Flags: Fragment;"]
[1013,"'CDH15'",32,27,21,26.6666666666667,"04514///Cell adhesion molecules (CAMs)","H00773///Autosomal dominant mental retardation",null,null,"GO:0005901///caveola+++GO:0031594///neuromuscular junction+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0016342///catenin complex","GO:0008092///cytoskeletal protein binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0003674///molecular_function+++GO:0042803///protein homodimerization activity","GO:0042060///wound healing+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:1902910///positive regulation of melanosome transport+++GO:0050896///response to stimulus+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0022405///hair cycle process+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0042493///response to drug+++GO:0007155///cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0007601///visual perception+++GO:0031424///keratinization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051796///negative regulation of timing of catagen+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0007043///cell-cell junction assembly+++GO:0001895///retina homeostasis+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation","cadherin 15","[CAD15_HUMAN|Reviewed]RecName: Full=Cadherin-15; AltName: Full=Cadherin-14; AltName: Full=Muscle cadherin; Short=M-cadherin; Flags: Precursor;+++[J3KRQ1_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000462111}; Flags: Fragment;+++[J3QKW6_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463267}; Flags: Fragment;+++[J3QL41_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463364}; Flags: Fragment;+++[J3QL75_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463415}; Flags: Fragment;+++[J3QR34_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464021};+++[J3QR60_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464058}; Flags: Fragment;"]
[10130,"'PDIA6'",6119,5446,5327,5630.66666666667,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0042470///melanosome+++GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0003756///protein disulfide isomerase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0006457///protein folding+++GO:0044267///cellular protein metabolic process+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process","protein disulfide isomerase family A member 6","[PDIA6_HUMAN|Reviewed]RecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1 {ECO:0000269|PubMed:12204115, ECO:0000269|PubMed:15466936}; AltName: Full=Endoplasmic reticulum protein 5; Short=ER protein 5; Short=ERp5; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor;+++[C9JNG5_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A6 {ECO:0000313|Ensembl:ENSP00000389558}; Flags: Fragment;"]
[10131,"'TRAP1'",1730,2008,1804,1847.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005759///mitochondrial matrix","GO:0051082///unfolded protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003723///RNA binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0061077///chaperone-mediated protein folding+++GO:0009386///translational attenuation+++GO:1901856///negative regulation of cellular respiration+++GO:0006950///response to stress+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process","TNF receptor associated protein 1","[TRAP1_HUMAN|Reviewed]RecName: Full=Heat shock protein 75 kDa, mitochondrial; Short=HSP 75; AltName: Full=TNFR-associated protein 1; AltName: Full=Tumor necrosis factor type 1 receptor-associated protein; Short=TRAP-1; Flags: Precursor;+++[A0A140VJY2_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 209 {ECO:0000313|EMBL:AEE61119.1};+++[I3L0K7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458166}; SubName: Full=TNF receptor-associated protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW85339.1};+++[I3L0P6_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458244}; Flags: Fragment;+++[I3L239_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459354}; Flags: Fragment;+++[I3L253_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459385}; Flags: Fragment;+++[I3L2D5_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459585}; Flags: Fragment;+++[I3L3L4_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000460545};+++[I3L4L7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000461354};+++[K0A7K7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:AFS69159.1}; Flags: Fragment;+++[Q53FS6_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 variant {ECO:0000313|EMBL:BAD96925.1}; Flags: Fragment;+++[Q5CAQ4_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:CAI64498.1}; SubName: Full=cDNA FLJ33058 fis, clone TRACH1000181, highly similar to Heat shock protein 75 kDa, mitochondrial {ECO:0000313|EMBL:BAG51942.1};+++[Q9BV61_HUMAN|Unreviewed]SubName: Full=TRAP1 protein {ECO:0000313|EMBL:AAH01455.2}; Flags: Fragment;"]
[10133,"'OPTN'",1701,1617,1495,1604.33333333333,"04137///Mitophagy - animal","H00612///Primary open angle glaucoma+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0055037///recycling endosome+++GO:0005802///trans-Golgi network+++GO:0005776///autophagosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005634///nucleus","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0030674///protein binding, bridging+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding","GO:0045087///innate immune response+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016192///vesicle-mediated transport+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007030///Golgi organization+++GO:0090161///Golgi ribbon formation+++GO:1904417///positive regulation of xenophagy+++GO:0006914///autophagy+++GO:0001920///negative regulation of receptor recycling+++GO:0008219///cell death+++GO:0034067///protein localization to Golgi apparatus+++GO:0034620///cellular response to unfolded protein+++GO:0002376///immune system process+++GO:0050829///defense response to Gram-negative bacterium+++GO:0034613///cellular protein localization+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0010508///positive regulation of autophagy+++GO:0007165///signal transduction","optineurin","[OPTN_HUMAN|Reviewed]RecName: Full=Optineurin; AltName: Full=E3-14.7K-interacting protein; AltName: Full=FIP-2; AltName: Full=Huntingtin yeast partner L; AltName: Full=Huntingtin-interacting protein 7; Short=HIP-7; AltName: Full=Huntingtin-interacting protein L; AltName: Full=NEMO-related protein; AltName: Full=Optic neuropathy-inducing protein; AltName: Full=Transcription factor IIIA-interacting protein; Short=TFIIIA-IntP;+++[A0A087WY28_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000481473}; Flags: Fragment;+++[A0A087X2G2_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000484961};+++[A0A0S2Z500_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 1 {ECO:0000313|EMBL:ALQ33960.1}; Flags: Fragment;+++[A0A0S2Z5I6_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 3 {ECO:0000313|EMBL:ALQ33961.1};+++[H7C1H4_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000400356}; Flags: Fragment;+++[X6RKL2_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 4 {ECO:0000313|EMBL:ALQ33962.1};"]
[10134,"'BCAP31'",2499,2288,2237,2341.33333333333,"05165///Human papillomavirus infection+++04141///Protein processing in endoplasmic reticulum","H00849///Creatine deficiency syndrome+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0030136///clathrin-coated vesicle+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0032580///Golgi cisterna membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0005784///Sec61 translocon complex+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005811///lipid droplet+++GO:0005887///integral component of plasma membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0042288///MHC class I protein binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0015031///protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007283///spermatogenesis+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0006886///intracellular protein transport+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:0016192///vesicle-mediated transport+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0006915///apoptotic process","B cell receptor associated protein 31","[BAP31_HUMAN|Reviewed]RecName: Full=B-cell receptor-associated protein 31; Short=BCR-associated protein 31; Short=Bap31; AltName: Full=6C6-AG tumor-associated antigen; AltName: Full=Protein CDM; AltName: Full=p28;+++[A0A2R8Y5M6_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000494936};+++[C9J0M4_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000400345}; Flags: Fragment;+++[C9JM14_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000402342}; Flags: Fragment;+++[C9JMD7_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000389740}; Flags: Fragment;+++[C9JQ75_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000409888}; Flags: Fragment;+++[C9JSP1_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000394270}; Flags: Fragment;"]
[10135,"'NAMPT'",290,278,279,282.333333333333,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways+++04621///NOD-like receptor signaling pathway",null,null,"R01271///nicotinamide-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase   Nicotinamide D-ribonucleotide + Diphosphate <=> Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate","GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0005615///extracellular space","GO:0042803///protein homodimerization activity+++GO:0008144///drug binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047280///nicotinamide phosphoribosyltransferase activity+++GO:0042802///identical protein binding+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0005125///cytokine activity","GO:0014070///response to organic cyclic compound+++GO:0009435///NAD biosynthetic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0060612///adipose tissue development+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0001774///microglial cell activation+++GO:0008284///positive regulation of cell proliferation+++GO:1905377///response to D-galactose+++GO:0070997///neuron death+++GO:0032922///circadian regulation of gene expression+++GO:0007568///aging+++GO:0010469///regulation of signaling receptor activity+++GO:1904646///cellular response to amyloid-beta+++GO:0007565///female pregnancy+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0010507///negative regulation of autophagy+++GO:0007267///cell-cell signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0007623///circadian rhythm+++GO:0048511///rhythmic process+++GO:0034356///NAD biosynthesis via nicotinamide riboside salvage pathway+++GO:0014916///regulation of lung blood pressure","nicotinamide phosphoribosyltransferase","[NAMPT_HUMAN|Reviewed]RecName: Full=Nicotinamide phosphoribosyltransferase; Short=NAmPRTase; Short=Nampt; EC=2.4.2.12; AltName: Full=Pre-B-cell colony-enhancing factor 1; Short=Pre-B cell-enhancing factor; AltName: Full=Visfatin;+++[A0A024R718_HUMAN|Unreviewed]SubName: Full=Pre-B-cell colony enhancing factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW83384.1};+++[A0A0C4DFS8_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000346242};+++[C9JF35_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390896}; Flags: Fragment;+++[C9JG65_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390591}; Flags: Fragment;"]
[10137,"'RBM12'",1406,1531.96,1428,1455.32,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding",null,"RNA binding motif protein 12","[RBM12_HUMAN|Reviewed]RecName: Full=RNA-binding protein 12; AltName: Full=RNA-binding motif protein 12; AltName: Full=SH3/WW domain anchor protein in the nucleus; Short=SWAN;+++[A6PVI0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000392642}; Flags: Fragment;+++[A6PVI1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411692}; Flags: Fragment;+++[Q5JX62_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411036}; Flags: Fragment;"]
[10138,"'YAF2'",168.71,134.68,128,143.796666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity","GO:0070317///negative regulation of G0 to G1 transition+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","YY1 associated factor 2","[YAF2_HUMAN|Reviewed]RecName: Full=YY1-associated factor 2;+++[A0A0B4J255_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447863};+++[B4DJQ9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57510, highly similar to YY1-associated factor 2 {ECO:0000313|EMBL:BAG58921.1};+++[F8VRE5_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448533};+++[F8VZR2_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447686}; Flags: Fragment;+++[F8W0B9_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447217};+++[G3V1X5_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_g {ECO:0000313|EMBL:EAW57840.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448291};+++[G3V212_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_b {ECO:0000313|EMBL:EAW57835.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450097};+++[G3V219_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_d {ECO:0000313|EMBL:EAW57837.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450394};"]
[10139,"'ARFRP1'",328,379,348,351.666666666667,"04060///Cytokine-cytokine receptor interaction","H00108///Autoimmune lymphoproliferative syndromes (ALPS)",null,null,"GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032588///trans-Golgi network membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:0007369///gastrulation+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007165///signal transduction+++GO:0033365///protein localization to organelle+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0034067///protein localization to Golgi apparatus+++GO:0006886///intracellular protein transport","ADP ribosylation factor related protein 1","[ARFRP_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-related protein 1; Short=ARF-related protein 1; Short=ARP;+++[B7ZKY8_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1 {ECO:0000313|EMBL:AAI43468.1};+++[H0UI96_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW75236.1};"]
[1014,"'CDH16'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0007267///cell-cell signaling+++GO:0007399///nervous system development","cadherin 16","[CAD16_HUMAN|Reviewed]RecName: Full=Cadherin-16; AltName: Full=Kidney-specific cadherin; Short=Ksp-cadherin; Flags: Precursor;"]
[10140,"'TOB1'",929,933,856,906,"03018///RNA degradation",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex","GO:0005515///protein binding+++GO:0046332///SMAD binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0003714///transcription corepressor activity+++GO:0030971///receptor tyrosine kinase binding","GO:0060212///negative regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0009967///positive regulation of signal transduction+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0017148///negative regulation of translation+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0008285///negative regulation of cell proliferation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0010468///regulation of gene expression+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening","transducer of ERBB2, 1","[TOB1_HUMAN|Reviewed]RecName: Full=Protein Tob1; AltName: Full=Transducer of erbB-2 1;"]
[101410538,"'MMP24OS'",5345,4565,4491,4800.33333333333,{"$nulls":7},"MMP24 opposite strand","[MMPOS_HUMAN|Reviewed]RecName: Full=Protein MMP24OS {ECO:0000305}; AltName: Full=MMP24 opposite strand {ECO:0000312|HGNC:HGNC:44421};"]
[10142,"'AKAP9'",1329.29,1462.9,1211,1334.39666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00720///Long QT syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0099147///extrinsic component of postsynaptic density membrane+++GO:0043025///neuronal cell body+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0044307///dendritic branch+++GO:0005795///Golgi stack+++GO:0097060///synaptic membrane+++GO:0005815///microtubule organizing center+++GO:0005801///cis-Golgi network+++GO:0008076///voltage-gated potassium channel complex+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0005813///centrosome","GO:0015459///potassium channel regulator activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0016301///kinase activity+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0034237///protein kinase A regulatory subunit binding","GO:0051602///response to electrical stimulus+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0007165///signal transduction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0016310///phosphorylation+++GO:1903358///regulation of Golgi organization+++GO:0071320///cellular response to cAMP+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0060306///regulation of membrane repolarization+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:0007268///chemical synaptic transmission+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0051661///maintenance of centrosome location+++GO:0031116///positive regulation of microtubule polymerization+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007020///microtubule nucleation+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0000086///G2/M transition of mitotic cell cycle","A-kinase anchoring protein 9","[AKAP9_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 9; Short=AKAP-9; AltName: Full=A-kinase anchor protein 350 kDa; Short=AKAP 350; Short=hgAKAP 350; AltName: Full=A-kinase anchor protein 450 kDa; Short=AKAP 450; AltName: Full=AKAP 120-like protein; AltName: Full=Centrosome- and Golgi-localized PKN-associated protein {ECO:0000303|PubMed:10358086}; Short=CG-NAP {ECO:0000303|PubMed:10358086}; AltName: Full=Protein hyperion {ECO:0000303|Ref.4}; AltName: Full=Protein kinase A-anchoring protein 9; Short=PRKA9; AltName: Full=Protein yotiao {ECO:0000303|PubMed:9482789};+++[A0A087WX84_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000480807};+++[A0A0A0MRE9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000350813};+++[A0A0A0MRF6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000351922};+++[A0A2R8Y590_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000494626}; Flags: Fragment;+++[A4D1E4_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9 {ECO:0000313|EMBL:EAL24158.1};+++[H0Y6Q0_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000406937}; Flags: Fragment;+++[H7BYL6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378042}; Flags: Fragment;+++[H7BZV6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000391704}; Flags: Fragment;+++[Q5GIA7_HUMAN|Unreviewed]SubName: Full=Antigen MU-RMS-40.16A {ECO:0000313|EMBL:AAT44400.1}; Flags: Fragment;+++[Q6PJH3_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9, isoform CRA_c {ECO:0000313|EMBL:EAW76862.1}; SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378065}; SubName: Full=AKAP9 protein {ECO:0000313|EMBL:AAH15533.1};"]
[10144,"'FAM13A'",2511,3013,2409,2644.33333333333,"04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","family with sequence similarity 13 member A","[FA13A_HUMAN|Reviewed]RecName: Full=Protein FAM13A;+++[A0A2X0SFT1_HUMAN|Unreviewed]SubName: Full=FAM13A {ECO:0000313|EMBL:SPT35754.1}; Flags: Fragment;+++[D6RCC1_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000423800};+++[D6RD35_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000427077};+++[D6RFM4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000426517};+++[D6RGE4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421269}; Flags: Fragment;+++[D6RIY4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000425784};+++[E9PGM7_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421914};+++[L0R4X6_HUMAN|Unreviewed]SubName: Full=Alternative protein FAM13A {ECO:0000313|EMBL:CCO13728.1};+++[Q6P521_HUMAN|Unreviewed]SubName: Full=FAM13A protein {ECO:0000313|EMBL:AAH63126.1}; SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000422345};"]
[10146,"'G3BP1'",992,959,923,958,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0043204///perikaryon+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0010494///cytoplasmic stress granule","GO:0004518///nuclease activity+++GO:0003676///nucleic acid binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0004519///endonuclease activity+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0003729///mRNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding","GO:0034063///stress granule assembly+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0032508///DNA duplex unwinding+++GO:0007265///Ras protein signal transduction","G3BP stress granule assembly factor 1","[G3BP1_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12 {ECO:0000269|PubMed:9889278}; EC=3.6.4.13 {ECO:0000269|PubMed:9889278}; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1;+++[E5RH00_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430045};+++[E5RH42_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429920}; Flags: Fragment;+++[E5RI46_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000428469}; Flags: Fragment;+++[E5RIF8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430738}; Flags: Fragment;+++[E5RIZ6_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429250}; Flags: Fragment;+++[E5RJU8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430480};+++[Q32P45_HUMAN|Unreviewed]SubName: Full=GTPase activating protein (SH3 domain) binding protein 1 {ECO:0000313|EMBL:AAI08279.1};+++[Q5U0Q1_HUMAN|Unreviewed]SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein {ECO:0000313|EMBL:AAV38191.1}; SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW61659.1}; SubName: Full=cDNA, FLJ92947, Homo sapiens Ras-GTPase-activating protein SH3-domain-bindingprotein (G3BP), mRNA {ECO:0000313|EMBL:BAG35467.1};+++[Q6FI03_HUMAN|Unreviewed]SubName: Full=G3BP protein {ECO:0000313|EMBL:CAG38772.1};+++[Q6ZP53_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1 {ECO:0000313|EMBL:BAC85272.1};"]
[10147,"'SUGP2'",1688.83,2436.97,2039.22,2055.00666666667,{"$nulls":4},"GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0006396///RNA processing+++GO:0008380///RNA splicing","SURP and G-patch domain containing 2","[SUGP2_HUMAN|Reviewed]RecName: Full=SURP and G-patch domain-containing protein 2; AltName: Full=Arginine/serine-rich-splicing factor 14; AltName: Full=Splicing factor, arginine/serine-rich 14;+++[A0A024R7K0_HUMAN|Unreviewed]SubName: Full=Splicing factor, arginine/serine-rich 14, isoform CRA_a {ECO:0000313|EMBL:EAW84768.1};+++[A8K5G0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76836, highly similar to Homo sapiens splicing factor, arginine/serine-rich 14 (SFRS14), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83964.1};+++[M0R065_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000471042}; Flags: Fragment;+++[M0R1Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472183}; Flags: Fragment;+++[M0R216_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472244}; Flags: Fragment;+++[M0R2Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472878}; Flags: Fragment;+++[M0R2Z9_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472914};+++[M0R3F6_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000473187};"]
[10148,"'EBI3'",9,13,22,14.6666666666667,{"$nulls":4},"GO:0070110///ciliary neurotrophic factor receptor complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043235///receptor complex+++GO:0097059///CNTFR-CLCF1 complex","GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0045523///interleukin-27 receptor binding+++GO:0019955///cytokine binding","GO:0006959///humoral immune response+++GO:0042088///T-helper 1 type immune response+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0070757///interleukin-35-mediated signaling pathway+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0042098///T cell proliferation","Epstein-Barr virus induced 3","[IL27B_HUMAN|Reviewed]RecName: Full=Interleukin-27 subunit beta; Short=IL-27 subunit beta; Short=IL-27B; AltName: Full=Epstein-Barr virus-induced gene 3 protein; Short=EBV-induced gene 3 protein; Flags: Precursor;"]
[10149,"'ADGRG2'",22,19,18,19.6666666666667,null,"H01033///Congenital bilateral absence of vas deferens",null,null,"GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome","GO:0004930///G protein-coupled receptor activity+++GO:0004888///transmembrane signaling receptor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007166///cell surface receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor G2","[AGRG2_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor G2 {ECO:0000303|PubMed:25713288}; AltName: Full=G-protein coupled receptor 64; AltName: Full=Human epididymis-specific protein 6; Short=He6; Flags: Precursor;+++[A0A024RC03_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64, isoform CRA_a {ECO:0000313|EMBL:EAW98954.1};+++[A8K4P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77493, highly similar to Homo sapiens G protein-coupled receptor 64 (GPR64), mRNA {ECO:0000313|EMBL:BAF83701.1};+++[Q14CE1_HUMAN|Unreviewed]SubName: Full=GPR64 protein {ECO:0000313|EMBL:AAI13979.1};+++[Q499H0_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64 {ECO:0000313|EMBL:AAH99901.1};"]
[1015,"'CDH17'",0,0,1,0.333333333333333,"05226///Gastric cancer",{"$nulls":3},"GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0005913///cell-cell adherens junction+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0005178///integrin binding+++GO:0046872///metal ion binding+++GO:0005215///transporter activity+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0005427///proton-dependent oligopeptide secondary active transmembrane transporter activity+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding","GO:0048536///spleen development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0035672///oligopeptide transmembrane transport+++GO:0033626///positive regulation of integrin activation by cell surface receptor linked signal transduction+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007229///integrin-mediated signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0007155///cell adhesion+++GO:0030183///B cell differentiation+++GO:0034332///adherens junction organization+++GO:0007043///cell-cell junction assembly+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0002314///germinal center B cell differentiation+++GO:0006857///oligopeptide transport+++GO:0002315///marginal zone B cell differentiation","cadherin 17","[CAD17_HUMAN|Reviewed]RecName: Full=Cadherin-17; AltName: Full=Intestinal peptide-associated transporter HPT-1; AltName: Full=Liver-intestine cadherin; Short=LI-cadherin; Flags: Precursor;+++[A0A0B4J288_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000455523};+++[E5RJT3_HUMAN|Unreviewed]SubName: Full=Cadherin-17 {ECO:0000313|Ensembl:ENSP00000428189}; Flags: Fragment;+++[E7EN24_HUMAN|Unreviewed]SubName: Full=Cadherin-17 {ECO:0000313|Ensembl:ENSP00000392811};+++[H0YBL0_HUMAN|Unreviewed]SubName: Full=Cadherin-17 {ECO:0000313|Ensembl:ENSP00000429730}; Flags: Fragment;+++[H3BSG2_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000456690};+++[H3BSV3_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000456891};+++[I3L418_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000460891}; Flags: Fragment;+++[J3QLA1_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000463451}; Flags: Fragment;"]
[10150,"'MBNL2'",1853,1698,1769,1773.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","muscleblind like splicing regulator 2","[MBNL2_HUMAN|Reviewed]RecName: Full=Muscleblind-like protein 2; AltName: Full=Muscleblind-like protein 1; AltName: Full=Muscleblind-like protein-like; AltName: Full=Muscleblind-like protein-like 39;+++[A0PJJ3_HUMAN|Unreviewed]SubName: Full=MBNL2 protein {ECO:0000313|EMBL:AAH32426.1}; Flags: Fragment;+++[A2A3S3_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAX08968.1}; SubName: Full=cDNA FLJ76890, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF84416.1}; SubName: Full=cDNA, FLJ79493, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF98735.1};+++[O95205_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAX08969.1}; SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000432422}; SubName: Full=Zinc finger protein {ECO:0000313|EMBL:AAC67242.1};+++[Q5JSC0_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000404202}; Flags: Fragment;"]
[10152,"'ABI2'",1424.07,1435,1348.59,1402.55333333333,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0032433///filopodium tip+++GO:0030054///cell junction+++GO:0031209///SCAR complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030175///filopodium+++GO:0005634///nucleus+++GO:0005912///adherens junction","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0017124///SH3 domain binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0048365///Rac GTPase binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0003674///molecular_function+++GO:0070064///proline-rich region binding","GO:0016032///viral process+++GO:0007399///nervous system development+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation+++GO:0008150///biological_process+++GO:0008154///actin polymerization or depolymerization+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0016601///Rac protein signal transduction+++GO:0007010///cytoskeleton organization","abl interactor 2","[ABI2_HUMAN|Reviewed]RecName: Full=Abl interactor 2 {ECO:0000303|Ref.16}; AltName: Full=Abelson interactor 2 {ECO:0000303|Ref.16}; Short=Abi-2 {ECO:0000303|PubMed:7590236}; AltName: Full=Abl-binding protein 3; Short=AblBP3; AltName: Full=Arg-binding protein 1 {ECO:0000303|PubMed:8649853}; Short=ArgBP1 {ECO:0000303|PubMed:8649853};+++[A0A0C4DG21_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000391433};+++[B7Z836_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51162, highly similar to Abl interactor 2 {ECO:0000313|EMBL:BAH13822.1};+++[E7EP65_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000414703}; Flags: Fragment;+++[E7EUA1_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000398487};+++[E7EW77_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000396249};+++[E9PEZ7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408898};+++[F8WAL6_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000261018};+++[F8WAQ3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000410509}; Flags: Fragment;+++[F8WAU3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405255};+++[F8WAZ8_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000397850};+++[F8WBL5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405801};+++[F8WCD7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000399040};+++[F8WEB9_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408334};+++[H0Y6B5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000404352}; Flags: Fragment;+++[H7C3Q7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000413375}; Flags: Fragment;+++[Q13802_HUMAN|Unreviewed]SubName: Full=ArgBPIB protein {ECO:0000313|EMBL:CAA64980.1};+++[Q53RS4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14935.1}; Flags: Fragment;+++[Q53SH3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14675.1}; Flags: Fragment;"]
[10153,"'CEBPZ'",395,392,350,379,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","CCAAT enhancer binding protein zeta","[CEBPZ_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein zeta; AltName: Full=CCAAT-box-binding transcription factor; Short=CBF; Short=CCAAT-binding factor;+++[C9J9W7_HUMAN|Unreviewed]SubName: Full=CCAAT/enhancer-binding protein zeta {ECO:0000313|Ensembl:ENSP00000391881}; Flags: Fragment;"]
[10154,"'PLXNC1'",2,5,4,3.66666666666667,"04360///Axon guidance","H00537///Nephronophthisis",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0002116///semaphorin receptor complex","GO:0017154///semaphorin receptor activity+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0007162///negative regulation of cell adhesion+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:0008360///regulation of cell shape+++GO:0030334///regulation of cell migration+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007165///signal transduction+++GO:0050772///positive regulation of axonogenesis+++GO:0043087///regulation of GTPase activity+++GO:0007155///cell adhesion","plexin C1","[PLXC1_HUMAN|Reviewed]RecName: Full=Plexin-C1; AltName: Full=Virus-encoded semaphorin protein receptor; AltName: CD_antigen=CD232; Flags: Precursor;+++[B4DHQ7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60256, highly similar to Plexin-C1 {ECO:0000313|EMBL:BAG58219.1};+++[F5H3A2_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000439225};+++[F8VUW4_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447843}; Flags: Fragment;+++[F8W095_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447625}; Flags: Fragment;+++[F8W1K6_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000446781};"]
[10155,"'TRIM28'",5210,5218,5255,5227.66666666667,{"$nulls":4},"GO:0005720///nuclear heterochromatin+++GO:0000785///chromatin+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005719///nuclear euchromatin","GO:0043565///sequence-specific DNA binding+++GO:0035851///Krueppel-associated box domain binding+++GO:1990841///promoter-specific chromatin binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0070087///chromo shadow domain binding+++GO:0003714///transcription corepressor activity+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0007566///embryo implantation+++GO:0016567///protein ubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0060669///embryonic placenta morphogenesis+++GO:1901536///negative regulation of DNA demethylation+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0060028///convergent extension involved in axis elongation+++GO:0006281///DNA repair+++GO:0007265///Ras protein signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0051259///protein complex oligomerization+++GO:1902187///negative regulation of viral release from host cell+++GO:0045087///innate immune response+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:2000653///regulation of genetic imprinting+++GO:0042307///positive regulation of protein import into nucleus+++GO:0006325///chromatin organization+++GO:0016925///protein sumoylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045739///positive regulation of DNA repair+++GO:0006468///protein phosphorylation+++GO:0043045///DNA methylation involved in embryo development+++GO:0016032///viral process+++GO:0043388///positive regulation of DNA binding","tripartite motif containing 28","[TIF1B_HUMAN|Reviewed]RecName: Full=Transcription intermediary factor 1-beta; Short=TIF1-beta; AltName: Full=E3 SUMO-protein ligase TRIM28; EC=2.3.2.27; AltName: Full=KRAB-associated protein 1; Short=KAP-1; AltName: Full=KRAB-interacting protein 1; Short=KRIP-1; AltName: Full=Nuclear corepressor KAP-1; AltName: Full=RING finger protein 96; AltName: Full=RING-type E3 ubiquitin transferase TIF1-beta {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 28;+++[M0QZE6_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000470503}; Flags: Fragment;+++[M0R0K9_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000471303}; Flags: Fragment;+++[M0R2I3_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000472586}; Flags: Fragment;+++[M0R3C0_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000473126}; Flags: Fragment;"]
[10156,"'RASA4'",332.7,350.35,274.26,319.103333333333,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding+++GO:0005543///phospholipid binding","GO:0071277///cellular response to calcium ion+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0034260///negative regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0007165///signal transduction","RAS p21 protein activator 4","[RASL2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4; AltName: Full=Calcium-promoted Ras inactivator; AltName: Full=Ras p21 protein activator 4; AltName: Full=RasGAP-activating-like protein 2;+++[A0A087WUJ9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000478719};+++[B7ZL55_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI43585.1};+++[E5RGQ8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428732}; Flags: Fragment;+++[E5RID2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428448}; Flags: Fragment;+++[E5RK78_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430418}; Flags: Fragment;+++[E7ERK1_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000417395};+++[H0YB35_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428605}; Flags: Fragment;+++[H0YBU2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430337}; Flags: Fragment;+++[Q2NL74_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI10874.1};"]
[10157,"'AASS'",545.03,604.42,569.53,572.993333333333,"01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00310///Lysine degradation+++01100///Metabolic pathways","H01242///Saccharopinuria+++H00188///Hyperlysinemia","M00032///Lysine degradation, lysine => saccharopine => acetoacetyl-CoA","R02313///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase; N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADH + H++++R00716///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADPH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0047130///saccharopine dehydrogenase (NADP+, L-lysine-forming) activity+++GO:0047131///saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity+++GO:0004753///saccharopine dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0003824///catalytic activity","GO:0019878///lysine biosynthetic process via aminoadipic acid+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine+++GO:0051262///protein tetramerization+++GO:0006554///lysine catabolic process+++GO:0019477///L-lysine catabolic process+++GO:0055114///oxidation-reduction process+++GO:0008152///metabolic process","aminoadipate-semialdehyde synthase","[AASS_HUMAN|Reviewed]RecName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial; AltName: Full=LKR/SDH; Includes: RecName: Full=Lysine ketoglutarate reductase; Short=LKR; Short=LOR; EC=1.5.1.8; Includes: RecName: Full=Saccharopine dehydrogenase; Short=SDH; EC=1.5.1.9; Flags: Precursor;+++[A4D0W4_HUMAN|Unreviewed]SubName: Full=Aminoadipate-semialdehyde synthase, isoform CRA_a {ECO:0000313|EMBL:EAW83564.1};+++[F8WAH1_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000351834};+++[F8WE53_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000414001};+++[H7C0C6_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000394180}; Flags: Fragment;"]
[10158,"'PDZK1IP1'",10,11,11,10.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane",null,null,"PDZK1 interacting protein 1","[PDZ1I_HUMAN|Reviewed]RecName: Full=PDZK1-interacting protein 1; AltName: Full=17 kDa membrane-associated protein; AltName: Full=Protein DD96;"]
[10159,"'ATP6AP2'",1501,1140,1283,1308,"04614///Renin-angiotensin system","H00658///Syndromic X-linked mental retardation",null,null,"GO:0044297///cell body+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0009897///external side of plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection","GO:0038023///signaling receptor activity+++GO:0019899///enzyme binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0060323///head morphogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021903///rostrocaudal neural tube patterning+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0048069///eye pigmentation+++GO:0002003///angiotensin maturation+++GO:0043408///regulation of MAPK cascade","ATPase H+ transporting accessory protein 2","[RENR_HUMAN|Reviewed]RecName: Full=Renin receptor; AltName: Full=ATPase H(+)-transporting lysosomal accessory protein 2; AltName: Full=ATPase H(+)-transporting lysosomal-interacting protein 2; AltName: Full=ER-localized type I transmembrane adaptor; AltName: Full=Embryonic liver differentiation factor 10; AltName: Full=N14F; AltName: Full=Renin/prorenin receptor; AltName: Full=Vacuolar ATP synthase membrane sector-associated protein M8-9; Short=ATP6M8-9; Short=V-ATPase M8.9 subunit; Flags: Precursor;+++[A0A1B0GTB0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489622}; Flags: Fragment;+++[A0A1B0GTD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489653};+++[A0A1B0GTU8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489845};+++[A0A1B0GU12_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489920};+++[A0A1B0GUT7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490239};+++[A0A1B0GUV3_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490257}; Flags: Fragment;+++[A0A1B0GV24_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490345};+++[A0A1B0GV60_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490382};+++[A0A1B0GVB9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490452};+++[A0A1B0GVC7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490462};+++[A0A1B0GVI9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490532};+++[A0A1B0GVW0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490675};+++[A0A1B0GVZ1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490706};+++[A0A1B0GW13_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490733};+++[A0A1B0GWD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490884}; Flags: Fragment;+++[A0A1B0GWJ8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490954};+++[A0A1C7CYW4_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000367697};+++[B7Z1I9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59846, highly similar to Renin receptor {ECO:0000313|EMBL:BAH11525.1};+++[B7Z413_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52527, highly similar to Renin receptor {ECO:0000313|EMBL:BAH12399.1};+++[H7C240_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000403969}; Flags: Fragment;+++[H7C3E1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000411317};"]
[1016,"'CDH18'",0,2,5,2.33333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0005913///cell-cell adherens junction+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex","GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0045294///alpha-catenin binding+++GO:0070097///delta-catenin binding+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0008013///beta-catenin binding","GO:0007155///cell adhesion+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0098609///cell-cell adhesion+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0044331///cell-cell adhesion mediated by cadherin","cadherin 18","[CAD18_HUMAN|Reviewed]RecName: Full=Cadherin-18; AltName: Full=Cadherin-14; Flags: Precursor;+++[D6RER2_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000424931};+++[D6RIH8_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000425854};+++[H0YAK3_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000427383}; Flags: Fragment;"]
[10160,"'FARP1'",1264,1310,1203,1259,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0048365///Rac GTPase binding","GO:0007275///multicellular organism development+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:0010923///negative regulation of phosphatase activity+++GO:1905606///regulation of presynapse assembly+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048813///dendrite morphogenesis+++GO:0007416///synapse assembly+++GO:0098974///postsynaptic actin cytoskeleton organization","FERM, ARH/RhoGEF and pleckstrin domain protein 1","[FARP1_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1; AltName: Full=Chondrocyte-derived ezrin-like protein; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 1; AltName: Full=Pleckstrin homology domain-containing family C member 2; Short=PH domain-containing family C member 2;+++[A0A1B0GV68_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000490391};+++[A0A2X0TVY0_HUMAN|Unreviewed]SubName: Full=FARP1 {ECO:0000313|EMBL:SPT35756.1}; SubName: Full=FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived) {ECO:0000313|EMBL:EAX08982.1}; Flags: Fragment;+++[C9JME2_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000471242};+++[H0Y783_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410930}; Flags: Fragment;+++[M0QXT1_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469365}; Flags: Fragment;+++[M0QYB0_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469712}; Flags: Fragment;+++[M0R262_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472346}; Flags: Fragment;"]
[10161,"'LPAR6'",6,4,2,4,"04151///PI3K-Akt signaling pathway+++04072///Phospholipase D signaling pathway+++05200///Pathways in cancer+++04080///Neuroactive ligand-receptor interaction","H00667///Woolly hair+++H00784///Localized autosomal recessive hypotrichosis",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0001835///blastocyst hatching+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction","lysophosphatidic acid receptor 6","[LPAR6_HUMAN|Reviewed]RecName: Full=Lysophosphatidic acid receptor 6; Short=LPA receptor 6; Short=LPA-6; AltName: Full=Oleoyl-L-alpha-lysophosphatidic acid receptor; AltName: Full=P2Y purinoceptor 5; Short=P2Y5; AltName: Full=Purinergic receptor 5; AltName: Full=RB intron encoded G-protein coupled receptor;+++[A0A024RDT2_HUMAN|Unreviewed]SubName: Full=HCG30749, isoform CRA_a {ECO:0000313|EMBL:EAX08797.1};+++[B3KVQ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41064 fis, clone TRACH2001021, highly similar to P2Y PURINOCEPTOR 5 {ECO:0000313|EMBL:BAG53867.1};"]
[10162,"'LPCAT3'",884,861.79,923,889.596666666667,"00564///Glycerophospholipid metabolism+++04216///Ferroptosis",null,null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase   Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:0006629///lipid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling","lysophosphatidylcholine acyltransferase 3","[MBOA5_HUMAN|Reviewed]RecName: Full=Lysophospholipid acyltransferase 5; Short=LPLAT 5; EC=2.3.1.-; AltName: Full=1-acylglycerophosphocholine O-acyltransferase; EC=2.3.1.23; AltName: Full=1-acylglycerophosphoserine O-acyltransferase; EC=2.3.1.n6; AltName: Full=Lysophosphatidylcholine acyltransferase; Short=LPCAT; Short=Lyso-PC acyltransferase; AltName: Full=Lysophosphatidylcholine acyltransferase 3; Short=Lyso-PC acyltransferase 3; AltName: Full=Lysophosphatidylserine acyltransferase; Short=LPSAT; Short=Lyso-PS acyltransferase; AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 5; Short=O-acyltransferase domain-containing protein 5;+++[B7Z3N5_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000443166}; SubName: Full=cDNA FLJ59910, highly similar to Membrane bound O-acyltransferase domain-containing protein 5 {ECO:0000313|EMBL:BAH12271.1};+++[F5GYT3_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000440550};+++[F5H0M4_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000438765};+++[F5H680_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000437827};+++[F5H7K7_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000442454};"]
[10163,"'WASF2'",2760,2896,2865,2840.33333333333,"05132///Salmonella infection+++05231///Choline metabolism in cancer+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005911///cell-cell junction+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0031209///SCAR complex+++GO:0001726///ruffle+++GO:0005769///early endosome","GO:0045296///cadherin binding+++GO:0003779///actin binding+++GO:0017124///SH3 domain binding+++GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0035855///megakaryocyte development+++GO:0030032///lamellipodium assembly+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0001667///ameboidal-type cell migration+++GO:0030048///actin filament-based movement+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0001525///angiogenesis+++GO:0051497///negative regulation of stress fiber assembly+++GO:0006897///endocytosis+++GO:0016601///Rac protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0072673///lamellipodium morphogenesis+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0016032///viral process","WAS protein family member 2","[WASF2_HUMAN|Reviewed]RecName: Full=Wiskott-Aldrich syndrome protein family member 2; Short=WASP family protein member 2; AltName: Full=Protein WAVE-2; AltName: Full=Verprolin homology domain-containing protein 2;+++[Q05BU7_HUMAN|Unreviewed]SubName: Full=WASF2 protein {ECO:0000313|EMBL:AAH32724.1}; Flags: Fragment;"]
[10164,"'CHST4'",1,0,0,0.333333333333333,"00533///Glycosaminoglycan biosynthesis - keratan sulfate",{"$nulls":3},"GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0031228///intrinsic component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0016740///transferase activity","GO:0006955///immune response+++GO:0006790///sulfur compound metabolic process+++GO:0007267///cell-cell signaling+++GO:0006954///inflammatory response+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006477///protein sulfation+++GO:0016266///O-glycan processing+++GO:0007155///cell adhesion+++GO:0005975///carbohydrate metabolic process","carbohydrate sulfotransferase 4","[CHST4_HUMAN|Reviewed]RecName: Full=Carbohydrate sulfotransferase 4; EC=2.8.2.-; AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; Short=GST-3; AltName: Full=High endothelial cells N-acetylglucosamine 6-O-sulfotransferase; Short=HEC-GlcNAc6ST; AltName: Full=L-selectin ligand sulfotransferase; Short=LSST; AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 2; Short=GlcNAc6ST-2; Short=Gn6st-2;"]
[10165,"'SLC25A13'",769,747,700,738.666666666667,null,"H01305///Global cerebral hypomyelination+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00185///Citrullinemia (CTLN)",null,null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion","GO:0015183///L-aspartate transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0005313///L-glutamate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015172///acidic amino acid transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0005215///transporter activity+++GO:0046872///metal ion binding","GO:0006839///mitochondrial transport+++GO:0015810///aspartate transmembrane transport+++GO:0055085///transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0015813///L-glutamate transmembrane transport+++GO:0045333///cellular respiration+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0043490///malate-aspartate shuttle+++GO:0051592///response to calcium ion+++GO:0070778///L-aspartate transmembrane transport+++GO:0006094///gluconeogenesis","solute carrier family 25 member 13","[CMC2_HUMAN|Reviewed]RecName: Full=Calcium-binding mitochondrial carrier protein Aralar2; AltName: Full=Citrin; AltName: Full=Mitochondrial aspartate glutamate carrier 2; AltName: Full=Solute carrier family 25 member 13;+++[Q75KX8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07527.1}; Flags: Fragment;+++[Q75M55_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07513.1}; Flags: Fragment;+++[R4GN64_HUMAN|Unreviewed]SubName: Full=Calcium-binding mitochondrial carrier protein Aralar2 {ECO:0000313|Ensembl:ENSP00000473505};"]
[10166,"'SLC25A15'",93,92.99,106.92,97.6366666666667,null,"H01268///Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005664///nuclear origin of replication recognition complex+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0022857///transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0000064///L-ornithine transmembrane transporter activity","GO:0033314///mitotic DNA replication checkpoint+++GO:1990575///mitochondrial L-ornithine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0000050///urea cycle+++GO:0006270///DNA replication initiation+++GO:0000278///mitotic cell cycle+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006260///DNA replication","solute carrier family 25 member 15","[ORNT1_HUMAN|Reviewed]RecName: Full=Mitochondrial ornithine transporter 1; AltName: Full=Solute carrier family 25 member 15;+++[F2Z354_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000431429};+++[Q5VZD9_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000415826}; Flags: Fragment;"]
[10168,"'ZNF197'",258.87,257.77,242.1,252.913333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 197","[ZN197_HUMAN|Reviewed]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[C9JIP4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000390115}; Flags: Fragment;+++[C9JQH5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000394713}; Flags: Fragment;+++[F8WDZ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000402483};+++[F8WEU5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000334616};+++[M0QYR3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000470025};+++[Q4G1C8_HUMAN|Unreviewed]SubName: Full=ZNF197 protein {ECO:0000313|EMBL:AAH17584.1}; Flags: Fragment;+++[Q7Z6G1_HUMAN|Unreviewed]SubName: Full=Znf197 truncated protein {ECO:0000313|EMBL:AAP57399.1}; Flags: Fragment;+++[Q86XA2_HUMAN|Unreviewed]SubName: Full=ZNF20 protein {ECO:0000313|EMBL:AAH45814.1};"]
[10169,"'SERF2'",6090,6195,5819,6034.66666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008150///biological_process","small EDRK-rich factor 2","[SERF2_HUMAN|Reviewed]RecName: Full=Small EDRK-rich factor 2; AltName: Full=Gastric cancer-related protein VRG107; AltName: Full=Protein 4F5-related; Short=4F5rel; Short=h4F5rel;+++[B8ZZY7_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386316};+++[B9A031_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000387041};+++[C9JQZ0_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000394660}; Flags: Fragment;+++[F8WBN3_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386290};+++[F8WBV6_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000391027};"]
[1017,"'CDK2'",248,207,235,230,"04934///Cushing's syndrome+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++04914///Progesterone-mediated oocyte maturation+++05226///Gastric cancer+++05215///Prostate cancer+++04151///PI3K-Akt signaling pathway+++04114///Oocyte meiosis+++05200///Pathways in cancer+++05162///Measles+++04218///Cellular senescence+++05203///Viral carcinogenesis+++04110///Cell cycle+++05168///Herpes simplex infection+++04068///FoxO signaling pathway+++05161///Hepatitis B+++05222///Small cell lung cancer+++05169///Epstein-Barr virus infection",null,"M00692///Cell cycle - G1/S transition+++M00693///Cell cycle - G2/M transition",null,"GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0097123///cyclin A1-CDK2 complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0000805///X chromosome+++GO:0097134///cyclin E1-CDK2 complex+++GO:0000781///chromosome, telomeric region+++GO:0097124///cyclin A2-CDK2 complex+++GO:0097135///cyclin E2-CDK2 complex+++GO:0000806///Y chromosome+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000793///condensed chromosome+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0015030///Cajal body+++GO:0005856///cytoskeleton","GO:0097472///cyclin-dependent protein kinase activity+++GO:0035173///histone kinase activity+++GO:0000287///magnesium ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0000166///nucleotide binding+++GO:0019904///protein domain specific binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0046872///metal ion binding","GO:0051301///cell division+++GO:0016310///phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006260///DNA replication+++GO:0006468///protein phosphorylation+++GO:0006813///potassium ion transport+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0018105///peptidyl-serine phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006281///DNA repair+++GO:0008284///positive regulation of cell proliferation+++GO:0032298///positive regulation of DNA-dependent DNA replication initiation+++GO:0051726///regulation of cell cycle+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0007099///centriole replication+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051298///centrosome duplication+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060968///regulation of gene silencing+++GO:0007049///cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016572///histone phosphorylation","cyclin dependent kinase 2","[CDK2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2; EC=2.7.11.22 {ECO:0000269|PubMed:1396589, ECO:0000269|PubMed:28666995, ECO:0000269|PubMed:9030781}; AltName: Full=Cell division protein kinase 2; AltName: Full=p33 protein kinase;+++[A0A024RB10_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW96857.1};+++[A0A024RB77_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_b {ECO:0000313|EMBL:EAW96860.1};+++[B4DDL9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54979, highly similar to Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG56780.1};+++[E7ESI2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000393605};+++[G3V317_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000450983};+++[G3V5T9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000452514}; SubName: Full=Cyclin-dependent kinase 2, isoform CRA_c {ECO:0000313|EMBL:EAW96859.1};"]
[10170,"'DHRS9'",3,2,1,2,"01100///Metabolic pathways+++00830///Retinol metabolism",null,null,"R02124///retinol:NAD+ oxidoreductase   Retinol + NAD+ <=> Retinal + NADH + H+","GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0016854///racemase and epimerase activity+++GO:0016491///oxidoreductase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0004022///alcohol dehydrogenase (NAD) activity","GO:0042572///retinol metabolic process+++GO:0030855///epithelial cell differentiation+++GO:0055114///oxidation-reduction process+++GO:0002138///retinoic acid biosynthetic process+++GO:0008209///androgen metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0042448///progesterone metabolic process","dehydrogenase/reductase 9","[DHRS9_HUMAN|Reviewed]RecName: Full=Dehydrogenase/reductase SDR family member 9; EC=1.1.-.-; AltName: Full=3-alpha hydroxysteroid dehydrogenase; Short=3-alpha-HSD; AltName: Full=NADP-dependent retinol dehydrogenase/reductase; AltName: Full=RDH-E2; AltName: Full=RDHL; AltName: Full=Retinol dehydrogenase 15; AltName: Full=Short chain dehydrogenase/reductase family 9C member 4; AltName: Full=Short-chain dehydrogenase/reductase retSDR8; AltName: Full=Tracheobronchial epithelial cell-specific retinol dehydrogenase; Short=RDH-TBE; Flags: Precursor;+++[C9J430_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 9 {ECO:0000313|Ensembl:ENSP00000391214}; Flags: Fragment;+++[Q4ZG83_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RDHL {ECO:0000313|EMBL:AAX88964.1}; Flags: Fragment;+++[Q53TL1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RDHL {ECO:0000313|EMBL:AAY24306.1}; Flags: Fragment;"]
[10171,"'RCL1'",151,153,125,143,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003824///catalytic activity+++GO:0004521///endoribonuclease activity","GO:0042254///ribosome biogenesis+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006396///RNA processing+++GO:0006364///rRNA processing+++GO:0008150///biological_process+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","RNA terminal phosphate cyclase like 1","[RCL1_HUMAN|Reviewed]RecName: Full=RNA 3'-terminal phosphate cyclase-like protein;+++[Q5VYW8_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000371151};+++[Q5VZU2_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000413381}; Flags: Fragment;+++[Q5VZU3_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000412000};"]
[10172,"'ZNF256'",45,46,47,46,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 256","[ZN256_HUMAN|Reviewed]RecName: Full=Zinc finger protein 256; AltName: Full=Bone marrow zinc finger 3; Short=BMZF-3;+++[L8E7T8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF256 {ECO:0000313|EMBL:CCQ43335.1};+++[M0R2X0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 256 {ECO:0000313|Ensembl:ENSP00000472858};"]
[10174,"'SORBS3'",3232,3358,3066,3218.66666666667,"04022///cGMP-PKG signaling pathway+++04662///B cell receptor signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04728///Dopaminergic synapse+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++04720///Long-term potentiation+++05014///Amyotrophic lateral sclerosis (ALS)+++04724///Glutamatergic synapse+++04380///Osteoclast differentiation+++04218///Cellular senescence+++05010///Alzheimer's disease+++04137///Mitophagy - animal+++04658///Th1 and Th2 cell differentiation+++04660///T cell receptor signaling pathway+++04659///Th17 cell differentiation+++04360///Axon guidance+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04370///VEGF signaling pathway+++04010///MAPK signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05031///Amphetamine addiction+++04310///Wnt signaling pathway+++04020///Calcium signaling pathway+++04625///C-type lectin receptor signaling pathway+++05166///HTLV-I infection+++04921///Oxytocin signaling pathway","H02150///Infantile or early childhood epileptic encephalopathy",null,null,"GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005856///cytoskeleton","GO:0017166///vinculin binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0008134///transcription factor binding","GO:0051495///positive regulation of cytoskeleton organization+++GO:0006936///muscle contraction+++GO:0043410///positive regulation of MAPK cascade+++GO:0051496///positive regulation of stress fiber assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0031589///cell-substrate adhesion+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion","sorbin and SH3 domain containing 3","[VINEX_HUMAN|Reviewed]RecName: Full=Vinexin; AltName: Full=SH3-containing adapter molecule 1; Short=SCAM-1; AltName: Full=Sorbin and SH3 domain-containing protein 3;+++[E5RIA0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429479}; Flags: Fragment;+++[E5RJP2_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000431128}; Flags: Fragment;+++[E7EQH0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429723};+++[H0YAU6_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428102}; Flags: Fragment;+++[H0YAZ3_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428327}; Flags: Fragment;+++[H0YB51_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428678}; Flags: Fragment;+++[Q9BT70_HUMAN|Unreviewed]SubName: Full=SORBS3 protein {ECO:0000313|EMBL:AAH04314.1}; Flags: Fragment;"]
[10175,"'CNIH1'",650,558,617,608.333333333333,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0012507///ER to Golgi transport vesicle membrane",null,"GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","cornichon family AMPA receptor auxiliary protein 1","[CNIH1_HUMAN|Reviewed]RecName: Full=Protein cornichon homolog 1; Short=CNIH-1; AltName: Full=Cornichon family AMPA receptor auxiliary protein 1; AltName: Full=Protein cornichon homolog; AltName: Full=T-cell growth-associated molecule 77; Short=TGAM77;+++[A8MVW4_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW80636.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000378940};+++[B2R4P1_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW80635.1}; SubName: Full=cDNA FLJ90300 fis, clone NT2RP2000533, highly similar to Cornichon homolog {ECO:0000313|EMBL:BAG52000.1}; SubName: Full=cDNA, FLJ92163, Homo sapiens cornichon homolog (Drosophila) (CNIH), mRNA {ECO:0000313|EMBL:BAG34838.1};+++[G3V3B2_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451142};+++[G3V474_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451640};+++[G3V4K0_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAW80637.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451852};+++[G3V5P8_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452457};+++[G3V5Q6_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452466};"]
[10178,"'TENM1'",3,4,5,4,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0043005///neuron projection+++GO:0016363///nuclear matrix+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0008201///heparin binding+++GO:0042803///protein homodimerization activity+++GO:0050839///cell adhesion molecule binding","GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0006955///immune response+++GO:0007218///neuropeptide signaling pathway+++GO:0090316///positive regulation of intracellular protein transport+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007165///signal transduction+++GO:0043406///positive regulation of MAP kinase activity+++GO:0008285///negative regulation of cell proliferation+++GO:0051491///positive regulation of filopodium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0048666///neuron development+++GO:0007399///nervous system development","teneurin transmembrane protein 1","[TEN1_HUMAN|Reviewed]RecName: Full=Teneurin-1; Short=Ten-1; AltName: Full=Protein Odd Oz/ten-m homolog 1; AltName: Full=Tenascin-M1; Short=Ten-m1; AltName: Full=Teneurin transmembrane protein 1; Contains: RecName: Full=Ten-1 intracellular domain; Short=IDten-1; Short=Ten-1 ICD; Contains: RecName: Full=Teneurin C-terminal-associated peptide; Short=TCPA-1; AltName: Full=Ten-1 extracellular domain; Short=Ten-1 ECD;+++[B7ZMH4_HUMAN|Unreviewed]SubName: Full=ODZ1 protein {ECO:0000313|EMBL:AAI44544.1};+++[G3CAS6_HUMAN|Unreviewed]SubName: Full=Odz, odd Oz/ten-m homolog 1 (Drosophila) {ECO:0000313|EMBL:CCD17865.1}; Flags: Fragment;+++[L8EAN5_HUMAN|Unreviewed]SubName: Full=Alternative protein ODZ1 {ECO:0000313|EMBL:CCQ43428.1};"]
[10179,"'RBM7'",240,246,229,238.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding","GO:0051321///meiotic cell cycle+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 7","[RBM7_HUMAN|Reviewed]RecName: Full=RNA-binding protein 7; AltName: Full=RNA-binding motif protein 7;+++[F5GXV8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440949};+++[F5GY08_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440923};+++[F5H606_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437998};+++[F5H674_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437847};+++[G3V1T9_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_a {ECO:0000313|EMBL:EAW67246.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000445848};+++[J3KPD3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_c {ECO:0000313|EMBL:EAW67248.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000364639};+++[Q6IRX3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7 {ECO:0000313|EMBL:AAH70262.1};"]
[1018,"'CDK3'",76,69,65,70,{"$nulls":4},"GO:0005634///nucleus","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0045023///G0 to G1 transition+++GO:0007049///cell cycle+++GO:0006468///protein phosphorylation+++GO:0008283///cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051301///cell division+++GO:0016310///phosphorylation","cyclin dependent kinase 3","[CDK3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 3; EC=2.7.11.22; AltName: Full=Cell division protein kinase 3;+++[A0A024R8R3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3, isoform CRA_a {ECO:0000313|EMBL:EAW89354.1};+++[K7EJ83_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000465062}; Flags: Fragment;+++[K7ELV5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000466237}; Flags: Fragment;"]
[10180,"'RBM6'",778,944,796,839.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006396///RNA processing","RNA binding motif protein 6","[RBM6_HUMAN|Reviewed]RecName: Full=RNA-binding protein 6; AltName: Full=Lung cancer antigen NY-LU-12; AltName: Full=Protein G16; AltName: Full=RNA-binding motif protein 6; AltName: Full=RNA-binding protein DEF-3;+++[A8K6Q4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76888, highly similar to Homo sapiens RNA binding motif protein 6 (RBM6), mRNA {ECO:0000313|EMBL:BAF84408.1};+++[C9J250_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000392475};+++[C9JII0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000403865}; Flags: Fragment;+++[C9JMC8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000389763}; Flags: Fragment;+++[C9JSL1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000394336}; Flags: Fragment;+++[E9PGM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396466};+++[F8WCA5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000406548};+++[F8WCT0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396410};+++[F8WF63_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000399942};"]
[10181,"'RBM5'",1903,2315,2004,2074,null,"H00943///TARP syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0008380///RNA splicing+++GO:0008285///negative regulation of cell proliferation+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006915///apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000245///spliceosomal complex assembly+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process","RNA binding motif protein 5","[RBM5_HUMAN|Reviewed]RecName: Full=RNA-binding protein 5; AltName: Full=Protein G15; AltName: Full=Putative tumor suppressor LUCA15; AltName: Full=RNA-binding motif protein 5; AltName: Full=Renal carcinoma antigen NY-REN-9;+++[A0A024R2U6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW65042.1};+++[A0A0S2Z549_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 1 {ECO:0000313|EMBL:ALQ33963.1}; Flags: Fragment;+++[A0A0S2Z5U0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 2 {ECO:0000313|EMBL:ALQ33964.1};+++[C9J9P7_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000406119}; Flags: Fragment;+++[C9JFQ5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000390711}; Flags: Fragment;+++[C9JR02_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000394622}; Flags: Fragment;+++[E1CJT4_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 variant {ECO:0000313|EMBL:BAJ19019.1};+++[F8W910_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000384872}; Flags: Fragment;+++[F8WE23_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000414218};+++[H7BYM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000378603}; Flags: Fragment;"]
[10184,"'LHFPL2'",870,841,800,837,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0031092///platelet alpha granule membrane+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0007338///single fertilization+++GO:1905516///positive regulation of fertilization+++GO:0002576///platelet degranulation+++GO:0046545///development of primary female sexual characteristics+++GO:0008150///biological_process+++GO:0046546///development of primary male sexual characteristics","LHFPL tetraspan subfamily member 2","[LHPL2_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 2 protein {ECO:0000312|HGNC:HGNC:6588}; AltName: Full=Lipoma HMGIC fusion partner-like 2 protein {ECO:0000312|HGNC:HGNC:6588};+++[A0A024RAM8_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW95819.1};"]
[10186,"'LHFPL6'",5360,6049,4872,5427,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","LHFPL tetraspan subfamily member 6","[LHPL6_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 6 protein {ECO:0000312|HGNC:HGNC:6586}; AltName: Full=Lipoma HMGIC fusion partner {ECO:0000312|HGNC:HGNC:6586}; Flags: Precursor;+++[A0A024RDR1_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner, isoform CRA_a {ECO:0000313|EMBL:EAX08617.1};"]
[10188,"'TNK2'",617,698,726,680.333333333333,{"$nulls":4},"GO:0005912///adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0097268///cytoophidium+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0070436///Grb2-EGFR complex+++GO:0005634///nucleus+++GO:0030136///clathrin-coated vesicle+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005905///clathrin-coated pit","GO:0016740///transferase activity+++GO:0005095///GTPase inhibitor activity+++GO:0042802///identical protein binding+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0050699///WW domain binding+++GO:0046872///metal ion binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0007264///small GTPase mediated signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0034260///negative regulation of GTPase activity+++GO:0030154///cell differentiation+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation","tyrosine kinase non receptor 2","[ACK1_HUMAN|Reviewed]RecName: Full=Activated CDC42 kinase 1; Short=ACK-1; EC=2.7.10.2 {ECO:0000269|PubMed:10652228, ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:16472662, ECO:0000269|PubMed:18993068, ECO:0000269|PubMed:20333297}; EC=2.7.11.1 {ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:18993068}; AltName: Full=Tyrosine kinase non-receptor protein 2;+++[B3KXJ4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45547 fis, clone BRTHA2035743, highly similar to Activated CDC42 kinase 1 {ECO:0000313|EMBL:BAG54506.1};+++[C9J1X3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392546};+++[C9JDG3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000395154}; Flags: Fragment;+++[C9JIR5_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390088}; Flags: Fragment;+++[F8WER3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000393707};+++[H0Y5H7_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000398614}; Flags: Fragment;+++[H7BZM8_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390435}; Flags: Fragment;+++[H7BZZ3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392253}; Flags: Fragment;+++[H7C343_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000409462}; Flags: Fragment;+++[H7C412_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000415126}; Flags: Fragment;"]
[10189,"'ALYREF'",930,791,799,840,"03013///RNA transport+++03040///Spliceosome+++05168///Herpes simplex infection+++03015///mRNA surveillance pathway",null,"M00406///TREX complex+++M00430///Exon junction complex (EJC)",null,"GO:0005681///spliceosomal complex+++GO:0070062///extracellular exosome+++GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0000784///nuclear chromosome, telomeric region+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0031124///mRNA 3'-end processing+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0001649///osteoblast differentiation+++GO:0051028///mRNA transport+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0016032///viral process+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000018///regulation of DNA recombination+++GO:0031297///replication fork processing","Aly/REF export factor","[THOC4_HUMAN|Reviewed]RecName: Full=THO complex subunit 4; Short=Tho4; AltName: Full=Ally of AML-1 and LEF-1; AltName: Full=Aly/REF export factor; AltName: Full=Transcriptional coactivator Aly/REF; AltName: Full=bZIP-enhancing factor BEF;+++[E9PB61_HUMAN|Unreviewed]SubName: Full=THO complex subunit 4 {ECO:0000313|Ensembl:ENSP00000421592};"]
[1019,"'CDK4'",1503,1451,1469.19,1474.39666666667,"05200///Pathways in cancer+++05162///Measles+++05223///Non-small cell lung cancer+++04115///p53 signaling pathway+++05166///HTLV-I infection+++05224///Breast cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05222///Small cell lung cancer+++05165///Human papillomavirus infection+++04110///Cell cycle+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++05219///Bladder cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05161///Hepatitis B+++04218///Cellular senescence+++05212///Pancreatic cancer+++05218///Melanoma+++05225///Hepatocellular carcinoma+++01522///Endocrine resistance+++05163///Human cytomegalovirus infection+++05220///Chronic myeloid leukemia+++05214///Glioma+++04660///T cell receptor signaling pathway+++04530///Tight junction+++04934///Cushing's syndrome","H00042///Glioma+++H00030///Cervical cancer+++H00038///Melanoma","M00692///Cell cycle - G1/S transition",null,"GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005730///nucleolus+++GO:0097129///cyclin D2-CDK4 complex+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000785///chromatin+++GO:0005923///bicellular tight junction+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005667///transcription factor complex","GO:0030332///cyclin binding+++GO:0016740///transferase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0044877///protein-containing complex binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0071157///negative regulation of cell cycle arrest+++GO:0046890///regulation of lipid biosynthetic process+++GO:0033574///response to testosterone+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0032869///cellular response to insulin stimulus+++GO:0071353///cellular response to interleukin-4+++GO:0050994///regulation of lipid catabolic process+++GO:0060612///adipose tissue development+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:0010033///response to organic substance+++GO:0043065///positive regulation of apoptotic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0002088///lens development in camera-type eye+++GO:0016310///phosphorylation+++GO:0010468///regulation of gene expression+++GO:0006468///protein phosphorylation+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007623///circadian rhythm+++GO:0055093///response to hyperoxia+++GO:0045727///positive regulation of translation+++GO:0045793///positive regulation of cell size+++GO:0051301///cell division+++GO:0007165///signal transduction+++GO:0040014///regulation of multicellular organism growth+++GO:0031100///animal organ regeneration+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:1904637///cellular response to ionomycin+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010288///response to lead ion+++GO:0009636///response to toxic substance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity","cyclin dependent kinase 4","[CDK4_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4; EC=2.7.11.22; AltName: Full=Cell division protein kinase 4; AltName: Full=PSK-J3;+++[A0A024RBB6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4, isoform CRA_a {ECO:0000313|EMBL:EAW97060.1};+++[F8VTV8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448098};+++[F8VWX7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449179}; Flags: Fragment;+++[F8VXD2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449391}; Flags: Fragment;+++[F8VYH9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448963}; Flags: Fragment;+++[F8VYY1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448885};+++[F8VZ13_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447005};+++[F8VZ51_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447779}; Flags: Fragment;+++[F8VZZ0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447274}; Flags: Fragment;+++[F8W1L8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000446763}; Flags: Fragment;+++[Q6LC83_HUMAN|Unreviewed]SubName: Full=Cyclin dependent protein kinase {ECO:0000313|EMBL:AAB50213.1}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_b {ECO:0000313|EMBL:EAW97059.1};+++[Q96BE9_HUMAN|Unreviewed]SubName: Full=CDK4 protein {ECO:0000313|EMBL:AAH15669.1}; SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000316889}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_c {ECO:0000313|EMBL:EAW97061.1};"]
[10190,"'TXNDC9'",240,192,186,206,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0008150///biological_process+++GO:0045454///cell redox homeostasis","thioredoxin domain containing 9","[TXND9_HUMAN|Reviewed]RecName: Full=Thioredoxin domain-containing protein 9; AltName: Full=ATP-binding protein associated with cell differentiation; AltName: Full=Protein 1-4;+++[B8ZZX4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000386889}; Flags: Fragment;+++[F8WBV5_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000391046};+++[F8WCJ3_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000406388};+++[G3XAJ4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain containing 9, isoform CRA_a {ECO:0000313|EMBL:EAX01868.1}; SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000402827};"]
[101927245,"'LOC101927245'",16,6,9,10.3333333333333,{"$nulls":7},"vegetative cell wall protein gp1-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927322,"'LOC101927322'",3,2,3,2.66666666666667,"04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++05152///Tuberculosis+++04064///NF-kappa B signaling pathway+++04662///B cell receptor signaling pathway",{"$nulls":3},"GO:0005730///nucleolus+++GO:0001650///fibrillar center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0032449///CBM complex+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0002020///protease binding+++GO:0043621///protein self-association+++GO:0042802///identical protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008233///peptidase activity","GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002726///positive regulation of T cell cytokine production+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006508///proteolysis+++GO:0050852///T cell receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:2000321///positive regulation of T-helper 17 cell differentiation+++GO:0051259///protein complex oligomerization+++GO:0001923///B-1 B cell differentiation+++GO:0009620///response to fungus+++GO:0002237///response to molecule of bacterial origin+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051168///nuclear export+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0042098///T cell proliferation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0006952///defense response+++GO:0032743///positive regulation of interleukin-2 production","uncharacterized LOC101927322","[MALT1_HUMAN|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1; EC=3.4.22.-; AltName: Full=MALT lymphoma-associated translocation; AltName: Full=Paracaspase;+++[MALT1_MOUSE|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; EC=3.4.22.-; AltName: Full=Paracaspase;"]
[101927345,"'LOC101927345'",9,3,11,7.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"putative ankyrin repeat domain-containing protein 20A12 pseudogene","[A2012_HUMAN|diamond]RecName: Full=Putative ankyrin repeat domain-containing protein 20A12 pseudogene {ECO:0000305};+++[AN18A_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18A;+++[AN18B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18B;+++[ANR26_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000305};+++[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[SNX18_MOUSE|diamond]RecName: Full=Sorting nexin-18; AltName: Full=Sorting nexin-associated Golgi protein 1;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927401,"'LOC101927401'",2,0,1,1,{"$nulls":4},"GO:0016604///nuclear body+++GO:0005886///plasma membrane+++GO:0030018///Z disc+++GO:0005829///cytosol+++GO:0031430///M band+++GO:0030016///myofibril+++GO:0042383///sarcolemma","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0008307///structural constituent of muscle+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005524///ATP binding+++GO:0031432///titin binding+++GO:0005516///calmodulin binding+++GO:0030506///ankyrin binding+++GO:0004674///protein serine/threonine kinase activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0036309///protein localization to M-band+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0045214///sarcomere organization+++GO:0035023///regulation of Rho protein signal transduction","MAGE-like protein 2","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[OBSCN_HUMAN|diamond]RecName: Full=Obscurin; EC=2.7.11.1 {ECO:0000250|UniProtKB:A2AAJ9}; AltName: Full=Obscurin-RhoGEF; AltName: Full=Obscurin-myosin light chain kinase; Short=Obscurin-MLCK;+++[OBSCN_MOUSE|diamond]RecName: Full=Obscurin; EC=2.7.11.1 {ECO:0000269|PubMed:23392350}; AltName: Full=Obscurin-RhoGEF; AltName: Full=Obscurin-myosin light chain kinase; Short=Obscurin-MLCK;+++[SPEG_DANRE|diamond]RecName: Full=Striated muscle preferentially expressed protein kinase; EC=2.7.11.1;+++[SPEG_MOUSE|diamond]RecName: Full=Striated muscle-specific serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[SPEG_RAT|diamond]RecName: Full=Striated muscle-specific serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927423,"'PANO1'",37,39,38,38,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus",null,"GO:0031647///regulation of protein stability+++GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process","proapoptotic nucleolar protein 1","[PANO1_HUMAN|Reviewed]RecName: Full=Proapoptotic nucleolar protein 1 {ECO:0000303|PubMed:22094112, ECO:0000312|HGNC:HGNC:51237};"]
[101927506,"'LOC101927506'",173.6,260.9,186.49,206.996666666667,"01100///Metabolic pathways+++04137///Mitophagy - animal+++00380///Tryptophan metabolism+++04140///Autophagy - animal",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin+++R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0005525///GTP binding","GO:0006310///DNA recombination+++GO:0007049///cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division+++GO:0032199///reverse transcription involved in RNA-mediated transposition","uncharacterized LOC101927506","[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NP10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Np9 protein; AltName: Full=HERV-K10 Np9 protein; AltName: Full=HERV-K107 Np9 protein; AltName: Full=HERV-K_5q33.3 provirus Np9 protein;+++[NP24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Np9 protein; AltName: Full=HERV-K101 Np9 protein; AltName: Full=HERV-K_22q11.21 provirus Np9 protein;+++[NP5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Np9 protein; AltName: Full=Endogenous retrovirus K protein 5; AltName: Full=HERV-K(II) Np9 protein; AltName: Full=HERV-K_3q12.3 provirus Np9 protein;+++[NP7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Np9 protein; AltName: Full=HERV-K(III) Np9 protein; AltName: Full=HERV-K102 Np9 protein; AltName: Full=HERV-K_1q22 provirus Np9 protein;+++[PRORY_HUMAN|diamond]RecName: Full=Proline-rich protein, Y-linked;+++[RL23A_BOVIN|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_HUMAN|diamond]RecName: Full=60S ribosomal protein L23a; AltName: Full=Large ribosomal subunit protein uL23 {ECO:0000303|PubMed:24524803};+++[RL23A_MOUSE|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_RAT|diamond]RecName: Full=60S ribosomal protein L23a;+++[SEP14_BOVIN|diamond]RecName: Full=Septin-14;+++[SEP14_HUMAN|diamond]RecName: Full=Septin-14;+++[SEP14_MOUSE|diamond]RecName: Full=Septin-14;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927509,"'LOC101927509'",23,14,26,21,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","basic proline-rich protein-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927572,"'LOC101927572'",1,1,1,1,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005795///Golgi stack+++GO:0032588///trans-Golgi network membrane+++GO:0005886///plasma membrane+++GO:0031901///early endosome membrane+++GO:0045121///membrane raft+++GO:0055038///recycling endosome membrane+++GO:0005802///trans-Golgi network","GO:0035594///ganglioside binding+++GO:0008017///microtubule binding","GO:0010828///positive regulation of glucose transmembrane transport+++GO:0072321///chaperone-mediated protein transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0001934///positive regulation of protein phosphorylation+++GO:0044091///membrane biogenesis+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0043065///positive regulation of apoptotic process+++GO:0045807///positive regulation of endocytosis+++GO:0045444///fat cell differentiation+++GO:0031115///negative regulation of microtubule polymerization","uncharacterized LOC101927572","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CLIP3_HUMAN|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP3_MOUSE|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP3_PONAB|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP3_XENLA|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP4_HUMAN|diamond]RecName: Full=CAP-Gly domain-containing linker protein 4; AltName: Full=Restin-like protein 2;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[KANK3_HUMAN|diamond]RecName: Full=KN motif and ankyrin repeat domain-containing protein 3; AltName: Full=Ankyrin repeat domain-containing protein 47;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927601,"'GOLGA6L19'",0,0.19,0,0.0633333333333333,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"golgin A6 family-like 19","[GG6LS_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 19;"]
[101927789,"'LOC101927789'",16,14,13,14.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated","putative ubiquitin-like protein FUBI-like protein ENSP00000310146","[GT2D2_BOVIN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GT2D2_MOUSE|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GTD2A_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2A; Short=GTF2I repeat domain-containing protein 2A; AltName: Full=Transcription factor GTF2IRD2-alpha;+++[GTD2B_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2B; Short=GTF2I repeat domain-containing protein 2B; AltName: Full=Transcription factor GTF2IRD2-beta;+++[NANGN_HUMAN|diamond]RecName: Full=NANOG neighbor homeobox; AltName: Full=Homeobox protein C14;+++[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[UBIML_HUMAN|diamond]RecName: Full=Putative ubiquitin-like protein FUBI-like protein ENSP00000310146;+++[UBIM_MOUSE|diamond]RecName: Full=Ubiquitin-like protein FUBI; AltName: Full=Monoclonal non-specific suppressor factor beta; Short=MNSF-beta;+++[UBIM_MUSSI|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_PIG|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_RAT|diamond]RecName: Full=Ubiquitin-like protein FUBI;"]
[101927824,"'LOC101927824'",5,5,3,4.33333333333333,{"$nulls":7},"translation initiation factor IF-2-like","[A0A1D5R5M3_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000055611};+++[A0A2K5TP44_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000001824};+++[A0A2K5UCW2_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000010203};+++[I7G9B2_MACFA|diamond]SubName: Full=Macaca fascicularis brain cDNA clone: QtrA-16029, similar to human glycoprotein VI (platelet) (GP6), mRNA, RefSeq: NM_016363.3 {ECO:0000313|EMBL:BAE91381.1};+++[Q95K85_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAB60791.1};"]
[101928095,"'LOC101928095'",7,8.03,6.76,7.26333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0003677///DNA binding+++GO:0004984///olfactory receptor activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0008270///zinc ion binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0015074///DNA integration+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0006310///DNA recombination","serine/arginine-rich splicing factor RSZ22-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[O7E24_HUMAN|diamond]RecName: Full=Olfactory receptor 7E24; AltName: Full=Olfactory receptor OR19-14;+++[OLF18_MOUSE|diamond]RecName: Full=Olfactory receptor 18; AltName: Full=Olfactory receptor 145-1; AltName: Full=Olfactory receptor TPCR34;+++[OR7AA_HUMAN|diamond]RecName: Full=Olfactory receptor 7A10; AltName: Full=OST027; AltName: Full=Olfactory receptor OR19-18;+++[OR7C2_HUMAN|diamond]RecName: Full=Olfactory receptor 7C2; AltName: Full=Olfactory receptor 19-18; Short=OR19-18; AltName: Full=Olfactory receptor 7C3; AltName: Full=Olfactory receptor OR19-22;+++[OR7D4_HUMAN|diamond]RecName: Full=Olfactory receptor 7D4; AltName: Full=OR19-B; AltName: Full=Odorant receptor family subfamily D member 4RT; AltName: Full=Olfactory receptor OR19-7;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101928120,"'LOC101928120'",40,40,29,36.3333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:1990907///beta-catenin-TCF complex","GO:0035034///histone acetyltransferase regulator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0030879///mammary gland development+++GO:0048589///developmental growth+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0001701///in utero embryonic development+++GO:0035563///positive regulation of chromatin binding+++GO:0002088///lens development in camera-type eye+++GO:0001822///kidney development+++GO:0009791///post-embryonic development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060021///roof of mouth development+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0007420///brain development+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0007289///spermatid nucleus differentiation","uncharacterized LOC101928120","[PYGO2_HUMAN|diamond]RecName: Full=Pygopus homolog 2;"]
[101928212,"'LOC101928212'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0030176///integral component of endoplasmic reticulum membrane","GO:0061513///glucose 6-phosphate:inorganic phosphate antiporter activity","GO:0015760///glucose-6-phosphate transport","uncharacterized LOC101928212","[A0A2K6U6V0_SAIBB|diamond]SubName: Full=Solute carrier family 37 member 1 {ECO:0000313|Ensembl:ENSSBOP00000027629};"]
[101928268,"'LOC101928268'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC101928268"]
[101928422,"'LOC101928422'",42.94,40.01,24.85,35.9333333333333,{"$nulls":4},"GO:0030054///cell junction+++GO:0005886///plasma membrane","GO:0044325///ion channel binding","GO:0090314///positive regulation of protein targeting to membrane+++GO:0030335///positive regulation of cell migration+++GO:0010360///negative regulation of anion channel activity","TRPM8 channel-associated factor 2-like","[TCAF1_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF1_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[TCAF1_PONAB|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF2_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF2_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 2 {ECO:0000303|PubMed:25559186};+++[TCAF2_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF3_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000312|MGI:MGI:3042585}; AltName: Full=Experimental autoimmune prostatitis antigen 2;+++[TCAF3_RAT|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000305}; AltName: Full=Experimental autoimmune prostatitis antigen 2 homolog;"]
[101928448,"'C5orf67'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome","GO:0048027///mRNA 5'-UTR binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:1902167///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006412///translation+++GO:1904803///regulation of translation involved in cellular response to UV+++GO:0006413///translational initiation+++GO:0042273///ribosomal large subunit biogenesis+++GO:0034644///cellular response to UV+++GO:0002181///cytoplasmic translation+++GO:0071480///cellular response to gamma radiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006364///rRNA processing+++GO:0045727///positive regulation of translation+++GO:1902164///positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","chromosome 5 open reading frame 67","[CE067_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf67;+++[A0A087WXD6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C5orf67 {ECO:0000313|Ensembl:ENSP00000480926};"]
[101928527,"'PIGBOS1'",111,99,86.88,98.96,{"$nulls":4},"GO:0005576///extracellular region",null,null,"PIGB opposite strand 1","[PIOS1_HUMAN|Reviewed]RecName: Full=Protein PIGBOS1 {ECO:0000305}; AltName: Full=PIGB opposite strand protein {ECO:0000312|HGNC:HGNC:50696}; Flags: Precursor;+++[A0A087WXK0_HUMAN|Unreviewed]SubName: Full=Protein PIGBOS1 {ECO:0000313|Ensembl:ENSP00000481097}; Flags: Fragment;"]
[101928589,"'LOC101928589'",130.85,81.56,143.78,118.73,{"$nulls":7},"uncharacterized LOC101928589","[A0A2Y9R3X6_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC111821147 {ECO:0000313|RefSeq:XP_023590205.1};+++[D3DUY5_HUMAN|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX02668.1}; Flags: Fragment;+++[G7NT51_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH30994.1}; Flags: Fragment;+++[G7Q3G6_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH61145.1}; Flags: Fragment;+++[Q9NXL7_HUMAN|diamond]SubName: Full=cDNA FLJ20173 fis, clone COL09814 {ECO:0000313|EMBL:BAA90993.1};"]
[101928592,"'LOC101928592'",3,1,1,1.66666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated","zinc finger protein OZF-like","[ZFP2_HUMAN|diamond]RecName: Full=Zinc finger protein 2 homolog; Short=Zfp-2; AltName: Full=Zinc finger protein 751;+++[ZFP2_MOUSE|diamond]RecName: Full=Zinc finger protein 2; Short=Zfp-2; AltName: Full=Protein mKR2;+++[ZKSC1_MOUSE|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;+++[ZKSC1_PONAB|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;+++[ZKSC7_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 7; AltName: Full=Zinc finger protein 167; AltName: Full=Zinc finger protein 448; AltName: Full=Zinc finger protein 64;+++[ZKSC8_PANTR|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 8; AltName: Full=Zinc finger protein 192;+++[ZN180_HUMAN|diamond]RecName: Full=Zinc finger protein 180; AltName: Full=HHZ168;+++[ZN197_HUMAN|diamond]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[ZN445_HUMAN|diamond]RecName: Full=Zinc finger protein 445; AltName: Full=Zinc finger protein 168; AltName: Full=Zinc finger protein with KRAB and SCAN domains 15;+++[ZNF3_HUMAN|diamond]RecName: Full=Zinc finger protein 3; AltName: Full=Zinc finger protein HF.12; AltName: Full=Zinc finger protein HZF3.1; AltName: Full=Zinc finger protein KOX25;"]
[101928601,"'MEI4'",0,2,4,2,{"$nulls":4},"GO:0005694///chromosome+++GO:0000800///lateral element","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0051321///meiotic cell cycle+++GO:0042138///meiotic DNA double-strand break formation+++GO:0048477///oogenesis+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0006310///DNA recombination","meiotic double-stranded break formation protein 4","[MEI4_HUMAN|Reviewed]RecName: Full=Meiosis-specific protein MEI4;"]
[101928635,"'LOC101928635'",12,12,11,11.6666666666667,"01100///Metabolic pathways+++04979///Cholesterol metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++00561///Glycerolipid metabolism+++04976///Bile secretion",null,"M00098///Acylglycerol degradation","R02250///triacylglycerol acylhydrolase Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase 1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid","GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016323///basolateral plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0034364///high-density lipoprotein particle+++GO:0016021///integral component of membrane","GO:0004806///triglyceride lipase activity+++GO:0004620///phospholipase activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0005345///purine nucleobase transmembrane transporter activity+++GO:0015288///porin activity+++GO:0046872///metal ion binding+++GO:0005372///water transmembrane transporter activity+++GO:0004170///dUTP diphosphatase activity+++GO:0046943///carboxylic acid transmembrane transporter activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0000287///magnesium ion binding+++GO:0015265///urea channel activity+++GO:0003677///DNA binding+++GO:0034185///apolipoprotein binding+++GO:0005350///pyrimidine nucleobase transmembrane transporter activity+++GO:0015166///polyol transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0008201///heparin binding+++GO:0051213///dioxygenase activity+++GO:0005275///amine transmembrane transporter activity+++GO:0015254///glycerol channel activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0015837///amine transport+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0006633///fatty acid biosynthetic process+++GO:0007588///excretion+++GO:0046942///carboxylic acid transport+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0034382///chylomicron remnant clearance+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006226///dUMP biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0015791///polyol transport+++GO:0006863///purine nucleobase transport+++GO:0034373///intermediate-density lipoprotein particle remodeling+++GO:0070328///triglyceride homeostasis+++GO:0010468///regulation of gene expression+++GO:0006955///immune response+++GO:0032197///transposition, RNA-mediated+++GO:0010033///response to organic substance+++GO:0006970///response to osmotic stress+++GO:0015855///pyrimidine nucleobase transport+++GO:0030104///water homeostasis+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0046689///response to mercury ion+++GO:0034638///phosphatidylcholine catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0019433///triglyceride catabolic process+++GO:0071320///cellular response to cAMP+++GO:0015793///glycerol transport+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0015722///canalicular bile acid transport+++GO:0046081///dUTP catabolic process+++GO:0006833///water transport+++GO:0043691///reverse cholesterol transport+++GO:0006310///DNA recombination","uncharacterized LOC101928635","[AQP10_MILTA|diamond]RecName: Full=Aquaporin-10 {ECO:0000303|PubMed:23761966}; Short=AQP-10 {ECO:0000303|PubMed:23761966};+++[AQP3_MOUSE|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=Aquaglyceroporin-3;+++[AQP3_RAT|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=31.4 kDa water channel protein; AltName: Full=Aquaglyceroporin-3;+++[AQP9_HUMAN|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9; AltName: Full=Small solute channel 1;+++[AQP9_MOUSE|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[AQP9_RAT|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DUT_HUMAN|diamond]RecName: Full=Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; Short=dUTPase; EC=3.6.1.23; AltName: Full=dUTP pyrophosphatase; Flags: Precursor;+++[DUTL_HUMAN|diamond]RecName: Full=Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323; Short=dUTPase-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LIPC_BOVIN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_HUMAN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_MOUSE|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RABIT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RAT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYL10_HUMAN|diamond]RecName: Full=Myosin regulatory light chain 10; AltName: Full=Myosin light chain 2, lymphocyte-specific; AltName: Full=Precursor lymphocyte-specific regulatory light chain;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928722,"'LOC101928722'",1,2,3,2,{"$nulls":4},"GO:0005813///centrosome","GO:0008017///microtubule binding","GO:0034453///microtubule anchoring","nascent polypeptide-associated complex subunit alpha, muscle-specific form-like","[A0A0D9RT94_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000011833};+++[A0A1W2PQX5_HUMAN|diamond]SubName: Full=Coiled-coil domain-containing protein 187 {ECO:0000313|Ensembl:ENSP00000492326};+++[A0A2I2Z933_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000043611};+++[A0A2R8ZH59_PANPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000003079};+++[H2RG04_PANTR|diamond]SubName: Full=CCDC187 isoform 3 {ECO:0000313|EMBL:PNI68580.1}; SubName: Full=Coiled-coil domain containing 187 {ECO:0000313|Ensembl:ENSPTRP00000060450};"]
[101928764,"'LOC101928764'",10,3,5,6,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005604///basement membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:0007154///cell communication+++GO:0048839///inner ear development+++GO:0001654///eye development+++GO:0042733///embryonic digit morphogenesis+++GO:0007507///heart development+++GO:0002009///morphogenesis of an epithelium","coiled-coil domain-containing protein 144B","[FREM2_HUMAN|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; Flags: Precursor;+++[FREM2_MOUSE|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; AltName: Full=NV domain-containing protein 1; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[POTB2_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B2;+++[POTB3_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B3 {ECO:0000312|HGNC:HGNC:51240};+++[POTEA_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member A; AltName: Full=ANKRD26-like family A member 1; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 8; Short=POTE-8;+++[POTEB_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B {ECO:0000305}; AltName: Full=ANKRD26-like family B member 1 {ECO:0000305}; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 15 {ECO:0000303|PubMed:15276201}; Short=POTE-15 {ECO:0000303|PubMed:15276201};+++[POTEC_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member C; AltName: Full=ANKRD26-like family B member 2; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 18; Short=POTE-18;"]
[101928841,"'LOC101928841'",16.95,24.05,23.72,21.5733333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","collagen alpha-1(II) chain-like","[FIBH_BOMMO|diamond]RecName: Full=Fibroin heavy chain; Short=Fib-H; AltName: Full=H-fibroin; Flags: Precursor;+++[PHXR5_MOUSE|diamond]RecName: Full=Putative per-hexamer repeat protein 5;+++[TPRX1_HUMAN|diamond]RecName: Full=Tetra-peptide repeat homeobox protein 1;+++[TSEP_GLOPP|diamond]RecName: Full=Protein TsetseEP; AltName: Full=EP-repeat protein; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928991,"'CCDC92B'",16.6,14.23,7.73,12.8533333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity",null,"coiled-coil domain containing 92B","[CCD92_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 92; AltName: Full=Limkain beta-2;+++[CCD92_MOUSE|diamond]RecName: Full=Coiled-coil domain-containing protein 92;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929097,"'101929097'",148.05,158.02,133.22,146.43,{"$nulls":8},"[H2NWX9_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000010497};+++[Q9H7L4_HUMAN|diamond]SubName: Full=FLJ00058 protein {ECO:0000313|EMBL:BAB15755.1}; Flags: Fragment;"]
[101929141,"'LOC101929141'",1,2,0,1,{"$nulls":7},"coiled-coil domain-containing protein 144B-like","[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;+++[C144B_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144B;+++[C144C_HUMAN|diamond]RecName: Full=Putative coiled-coil domain-containing protein 144C; AltName: Full=Coiled-coil domain-containing protein 144C pseudogene;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[POTEE_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member E; AltName: Full=ANKRD26-like family C member 1A; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 2; Short=POTE-2;+++[POTEF_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member F; AltName: Full=ANKRD26-like family C member 1B; AltName: Full=Chimeric POTE-actin protein;"]
[101929322,"'LOC101929322'",254,268,290.36,270.786666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0032587///ruffle membrane+++GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0016020///membrane","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding","GO:0043410///positive regulation of MAPK cascade+++GO:0000165///MAPK cascade+++GO:0016180///snRNA processing+++GO:0019933///cAMP-mediated signaling+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0006468///protein phosphorylation","integrator complex subunit 4 pseudogene","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[INT4_DICDI|diamond]RecName: Full=Integrator complex subunit 4 homolog;+++[INT4_DROME|diamond]RecName: Full=Integrator complex subunit 4 {ECO:0000303|PubMed:21078872};+++[INT4_HUMAN|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_MOUSE|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_XENLA|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929400,"'LOC101929400'",2,2.96,1.28,2.08,{"$nulls":5},"GO:0003723///RNA binding",null,"uncharacterized LOC101929400","[A0A2I2ZER1_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000045561};+++[A0A2I3HCP8_NOMLE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000041428};+++[A0A2I3T7A9_PANTR|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNI44179.1}; SubName: Full=RNA binding fox-1 homolog 1 {ECO:0000313|Ensembl:ENSPTRP00000085111};+++[A0A2J8SEY9_PONAB|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNJ19325.1};+++[A0A2J8SEZ1_PONAB|diamond]SubName: Full=RBFOX1 isoform 24 {ECO:0000313|EMBL:PNJ19336.1};"]
[101929479,"'LOC101929479'",500.71,629.56,526.67,552.313333333333,{"$nulls":4},"GO:0043202///lysosomal lumen+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0032580///Golgi cisterna membrane+++GO:0005796///Golgi lumen+++GO:0031258///lamellipodium membrane+++GO:0000922///spindle pole+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0016324///apical plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0072686///mitotic spindle","GO:0045296///cadherin binding+++GO:0061676///importin-alpha family protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0019905///syntaxin binding+++GO:0019901///protein kinase binding","GO:0007020///microtubule nucleation+++GO:0060050///positive regulation of protein glycosylation+++GO:0001525///angiogenesis+++GO:0006486///protein glycosylation+++GO:0051289///protein homotetramerization+++GO:0051225///spindle assembly+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0010507///negative regulation of autophagy+++GO:0090307///mitotic spindle assembly+++GO:0000187///activation of MAPK activity+++GO:0030207///chondroitin sulfate catabolic process+++GO:0048771///tissue remodeling+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0090161///Golgi ribbon formation+++GO:0090166///Golgi disassembly+++GO:0090306///spindle assembly involved in meiosis+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0032091///negative regulation of protein binding+++GO:0008356///asymmetric cell division+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0008283///cell proliferation+++GO:0007098///centrosome cycle+++GO:0035556///intracellular signal transduction+++GO:0008347///glial cell migration","golgin subfamily A member 2","[CSPG4_HUMAN|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Melanoma chondroitin sulfate proteoglycan; AltName: Full=Melanoma-associated chondroitin sulfate proteoglycan; Flags: Precursor;+++[CSPG4_MOUSE|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Proteoglycan AN2; Flags: Precursor;+++[CSPG4_RAT|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=HSN tumor-specific antigen; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DYN1_BOVIN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_HUMAN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_MOUSE|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_RAT|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5; AltName: Full=B-dynamin; AltName: Full=D100; AltName: Full=Dynamin, brain;+++[GGA2B_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 2B; AltName: Full=Golgin subfamily A member 2-like protein 1;+++[GOG6A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6A; AltName: Full=Golgin linked to PML; AltName: Full=Golgin-like protein;+++[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8A; AltName: Full=88 kDa Golgi matrix protein; Short=GM88; AltName: Full=GM88 autoantigen;+++[GOG8B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8B; AltName: Full=Golgin-67;+++[GOG8C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8C;+++[GOG8D_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POLY_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon gypsy; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;"]
[101929599,"'LOC101929599'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"putative POM121-like protein 1-like pseudogene","[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[101929738,"'LOC101929738'",1,1,0,0.666666666666667,{"$nulls":7},"putative POM121-like protein 1","[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[101929747,"'101929747'",4.3,16,16,12.1,{"$nulls":8},"[A0A2Y9JJD1_ENHLU|diamond]SubName: Full=uncharacterized protein LOC111148452 {ECO:0000313|RefSeq:XP_022360711.1};"]
[101929796,"'NOTCH2NLR'",89.01,90.21,65.9,81.7066666666667,"04330///Notch signaling pathway+++01522///Endocrine resistance+++04658///Th1 and Th2 cell differentiation+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++04320///Dorso-ventral axis formation","H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0005654///nucleoplasm+++GO:0043235///receptor complex+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005576///extracellular region","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007399///nervous system development+++GO:0007219///Notch signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006915///apoptotic process+++GO:0002315///marginal zone B cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007050///cell cycle arrest+++GO:0003184///pulmonary valve morphogenesis+++GO:0046849///bone remodeling+++GO:2001204///regulation of osteoclast development+++GO:0030097///hemopoiesis+++GO:0060413///atrial septum morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0001709///cell fate determination+++GO:0045967///negative regulation of growth rate+++GO:0009887///animal organ morphogenesis+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0061314///Notch signaling involved in heart development+++GO:0019827///stem cell population maintenance+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","notch 2 N-terminal like R","[NOTC2_HUMAN|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Short=hN2; Contains: RecName: Full=Notch 2 extracellular truncation; Short=N2ECD {ECO:0000303|PubMed:25985737}; Contains: RecName: Full=Notch 2 intracellular domain; Short=N2ICD {ECO:0000303|PubMed:25985737}; Flags: Precursor;+++[NOTC2_RAT|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Contains: RecName: Full=Notch 2 extracellular truncation; Contains: RecName: Full=Notch 2 intracellular domain; Flags: Precursor;+++[NT2NA_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[NT2NC_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[101929895,"'LOC101929895'",14,4,7,8.33333333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0043209///myelin sheath+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0008017///microtubule binding+++GO:0015631///tubulin binding","GO:0031334///positive regulation of protein complex assembly+++GO:0001578///microtubule bundle formation+++GO:0046785///microtubule polymerization+++GO:0032273///positive regulation of protein polymerization","uncharacterized LOC101929895","[TPPP_BOVIN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=p25-alpha;+++[TPPP_HUMAN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=TPPP/p25; AltName: Full=p24; AltName: Full=p25-alpha;+++[TPPP_MOUSE|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP;"]
[101929937,"'LOC101929937'",1,4,5,3.33333333333333,null,"H00773///Autosomal dominant mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0032993///protein-DNA complex+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0030133///transport vesicle","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0021510///spinal cord development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045165///cell fate commitment+++GO:0065004///protein-DNA complex assembly","uncharacterized LOC101929937","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[NRSN2_HUMAN|diamond]RecName: Full=Neurensin-2;+++[NRSN2_MOUSE|diamond]RecName: Full=Neurensin-2;+++[SOX11_CHICK|diamond]RecName: Full=Transcription factor SOX-11; Short=cSox11;+++[SOX11_XENTR|diamond]RecName: Full=Transcription factor Sox-11;+++[SOX12_HUMAN|diamond]RecName: Full=Transcription factor SOX-12; AltName: Full=Protein SOX-22;+++[SOX12_MOUSE|diamond]RecName: Full=Transcription factor SOX-12;+++[SX11B_XENLA|diamond]RecName: Full=Transcription factor Sox-11-B; AltName: Full=Transcription factor Sox-13; Short=xSox-13; AltName: Full=XLS13B;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929950,"'LOC101929950'",12.73,20.44,19.17,17.4466666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0042277///peptide binding","GO:0006508///proteolysis+++GO:0043171///peptide catabolic process","puromycin-sensitive aminopeptidase-like protein","[ERAP1_MOUSE|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 1; EC=3.4.11.-; AltName: Full=ARTS-1; AltName: Full=Adipocyte-derived leucine aminopeptidase; Short=A-LAP; AltName: Full=Aminopeptidase PILS; AltName: Full=Puromycin-insensitive leucyl-specific aminopeptidase; Short=PILS-AP; AltName: Full=VEGF-induced aminopeptidase;+++[ERAP2_BOVIN|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 2; EC=3.4.11.-;+++[PSA_CAEEL|diamond]RecName: Full=Puromycin-sensitive aminopeptidase {ECO:0000303|PubMed:12930831}; Short=PSA {ECO:0000305}; EC=3.4.11.14 {ECO:0000305|PubMed:12930831}; AltName: Full=Cytosol alanyl aminopeptidase {ECO:0000305}; Short=AAP-S {ECO:0000305};+++[PSA_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;+++[PSAL_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase-like protein; EC=3.4.11.-;+++[PSA_MOUSE|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;"]
[101929959,"'LOC101929959'",115.73,117.66,95.04,109.476666666667,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++03320///PPAR signaling pathway+++04140///Autophagy - animal+++04923///Regulation of lipolysis in adipocytes","H02106///Genetic obesity+++H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0030686///90S preribosome+++GO:0005730///nucleolus","GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0003723///RNA binding+++GO:0035252///UDP-xylosyltransferase activity+++GO:0034511///U3 snoRNA binding+++GO:0015267///channel activity+++GO:0003924///GTPase activity","GO:0006364///rRNA processing+++GO:0000479///endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0016266///O-glycan processing","ribosome biogenesis protein BMS1 homolog","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[AQP7_HUMAN|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7; AltName: Full=Aquaporin adipose; Short=AQPap; AltName: Full=Aquaporin-7-like;+++[AQP7_MACFA|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[AQP7_MOUSE|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[BMS1_HUMAN|diamond]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GXLT1_HUMAN|diamond]RecName: Full=Glucoside xylosyltransferase 1; EC=2.4.2.n2; AltName: Full=Glycosyltransferase 8 domain-containing protein 3;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[TSR1_DICDI|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_HUMAN|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_MOUSE|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_PONAB|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_XENLA|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10193,"'RNF41'",1258.53,1199.95,1172.63,1210.37,"04144///Endocytosis",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0071782///endoplasmic reticulum tubular network","GO:0004842///ubiquitin-protein transferase activity+++GO:0019904///protein domain specific binding+++GO:0017160///Ral GTPase binding+++GO:0005128///erythropoietin receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0005135///interleukin-3 receptor binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity","GO:0010498///proteasomal protein catabolic process+++GO:0051896///regulation of protein kinase B signaling+++GO:0051865///protein autoubiquitination+++GO:0006915///apoptotic process+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000114///regulation of establishment of cell polarity+++GO:0006914///autophagy+++GO:0045637///regulation of myeloid cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0010468///regulation of gene expression+++GO:1901525///negative regulation of mitophagy+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045619///regulation of lymphocyte differentiation+++GO:0000209///protein polyubiquitination+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0008285///negative regulation of cell proliferation+++GO:0043408///regulation of MAPK cascade+++GO:0016567///protein ubiquitination","ring finger protein 41","[RNF41_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase NRDP1; EC=2.3.2.27; AltName: Full=RING finger protein 41; AltName: Full=RING-type E3 ubiquitin transferase NRDP1 {ECO:0000305};+++[A0A024RB33_HUMAN|Unreviewed]SubName: Full=Ring finger protein 41, isoform CRA_b {ECO:0000313|EMBL:EAW96911.1};+++[F8VNZ6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000450164}; Flags: Fragment;+++[F8VSB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448187};+++[F8VSE5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448330};+++[F8VSP7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000446595}; Flags: Fragment;+++[F8VVY2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000449575};"]
[101930307,"'LOC101930307'",30,49,24,34.3333333333333,{"$nulls":4},"GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity","GO:0008152///metabolic process","uncharacterized LOC101930307","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101930434,"'LOC101930434'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0032580///Golgi cisterna membrane+++GO:0005794///Golgi apparatus",null,null,"putative golgin subfamily A member 8I","[GOG8H_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8H;+++[GOG8I_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8I {ECO:0000305}; AltName: Full=Golgin subfamily A member 8I pseudogene {ECO:0000305};+++[GOG8J_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8J;+++[GOG8K_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8K;+++[GOG8M_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8M;+++[GOG8N_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8N;+++[GOG8Q_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8Q {ECO:0000305};+++[GOG8T_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8T {ECO:0000305};"]
[10194,"'TSHZ1'",186,331,204,240.333333333333,"04391///Hippo signaling pathway - fly","H02115///Congenital aural atresia",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0009952///anterior/posterior pattern specification+++GO:0007275///multicellular organism development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060023///soft palate development+++GO:0042474///middle ear morphogenesis","teashirt zinc finger homeobox 1","[TSH1_HUMAN|Reviewed]RecName: Full=Teashirt homolog 1; AltName: Full=Antigen NY-CO-33; AltName: Full=Serologically defined colon cancer antigen 33;+++[A7YF73_HUMAN|Unreviewed]SubName: Full=TSHZ1 protein {ECO:0000313|EMBL:AAH24152.2}; Flags: Fragment;+++[H0YKA1_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000452718}; Flags: Fragment;+++[H0YN23_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000453834}; Flags: Fragment;"]
[10195,"'ALG3'",1562,1669,1585,1605.33333333333,"00513///Various types of N-glycan biosynthesis+++00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R06258///Dolichyl phosphate D-mannose + G00006 <=> Dolichyl phosphate + G10595","GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0005515///protein binding+++GO:0052925///dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0000030///mannosyltransferase activity+++GO:0000033///alpha-1,3-mannosyltransferase activity","GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006486///protein glycosylation+++GO:0097502///mannosylation","ALG3, alpha-1,3- mannosyltransferase","[ALG3_HUMAN|Reviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; EC=2.4.1.258; AltName: Full=Asparagine-linked glycosylation protein 3 homolog; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase; AltName: Full=Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase; AltName: Full=Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase; AltName: Full=Not56-like protein;+++[C9J7S5_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047};+++[F8WE30_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000394917};+++[F8WF93_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000407011};+++[H7BZZ2_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000392209}; Flags: Fragment;+++[H7C0X4_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; Flags: Fragment;"]
[10196,"'PRMT3'",123,83,102,102.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,null,"R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol","GO:0008168///methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0043022///ribosome binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0034969///histone arginine methylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032259///methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006479///protein methylation","protein arginine methyltransferase 3","[ANM3_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 3; EC=2.1.1.-; AltName: Full=Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3;+++[E9PLF6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000435151};+++[E9PRB4_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000434260};+++[Q8WUV3_HUMAN|Unreviewed]SubName: Full=PRMT3 protein {ECO:0000313|EMBL:AAH19339.1}; Flags: Fragment;"]
[10197,"'PSME3'",2076,1815,1969,1953.33333333333,"03050///Proteasome+++05160///Hepatitis C+++04612///Antigen processing and presentation",null,null,"R03139///primary-amine oxidase 1,3-Diaminopropane + Oxygen + H2O <=> 3-Aminopropanal + Ammonia + Hydrogen peroxide+++R06740///primary-amine oxidase Cadaverine + H2O + Oxygen <=> 5-Aminopentanal + Ammonia + Hydrogen peroxide+++R02613///Phenethylamine:oxygen oxidoreductase (deaminating) Phenethylamine + Oxygen + H2O <=> Phenylacetaldehyde + Ammonia + Hydrogen peroxide+++R06154///methylamine:oxygen oxidoreductase (deaminating) (copper-containing) Methylamine + Oxygen + H2O <=> Formaldehyde + Ammonia + Hydrogen peroxide+++R02529///aminoacetone:oxygen oxidoreductase(deaminating) Aminoacetone + H2O + Oxygen <=> Methylglyoxal + Ammonia + Hydrogen peroxide+++R02382///Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) Tyramine + H2O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04300///4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing) Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04027///primary-amine oxidase N-Methylputrescine + Oxygen + H+ <=> 1-Methylpyrrolinium + Hydrogen peroxide + Ammonia","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0008537///proteasome activator complex+++GO:0000502///proteasome complex","GO:0061133///endopeptidase activator activity+++GO:0002039///p53 binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007049///cell cycle+++GO:0043687///post-translational protein modification+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0006915///apoptotic process","proteasome activator subunit 3","[PSME3_HUMAN|Reviewed]RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma;+++[A0A024R203_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) activator subunit 3 (PA28 gamma Ki), isoform CRA_a {ECO:0000313|EMBL:EAW60894.1};+++[A0A087WTV2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000478159};+++[B3KQ25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32659 fis, clone TESTI1000045, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAG51887.1};+++[B7Z8D3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57249, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAH13919.1};+++[K7EJF8_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465155};+++[K7EKR3_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465743}; Flags: Fragment;+++[K7EMD0_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466451}; Flags: Fragment;+++[K7ENH2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466945}; Flags: Fragment;+++[K7EPX6_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000467580}; Flags: Fragment;+++[K7ESG5_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000468702};+++[K9J957_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000438237}; SubName: Full=REG gamma-3 variant {ECO:0000313|EMBL:ACO54885.1};+++[Q6FHK7_HUMAN|Unreviewed]SubName: Full=PSME3 protein {ECO:0000313|EMBL:CAG46545.1};+++[Q6MZZ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686J2076 {ECO:0000313|EMBL:CAE45884.1};+++[V9HWJ8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 283 {ECO:0000313|EMBL:ACJ13707.1};"]
[10198,"'MPHOSPH9'",204,217,208,209.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus",null,null,"M-phase phosphoprotein 9","[MPP9_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 9;+++[A0A0A0MTP3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000445859};+++[F5GYG6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440664}; Flags: Fragment;+++[F5GYP5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441298}; Flags: Fragment;+++[F5H1U6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446362}; Flags: Fragment;+++[F5H1W2_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446334}; Flags: Fragment;+++[F5H2I5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446249};+++[F5H798_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000442663};+++[H0YFS3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440007}; Flags: Fragment;+++[H0YG46_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441764}; Flags: Fragment;+++[J3KNE4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000304096}; Flags: Fragment;+++[U3KQ61_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475578}; Flags: Fragment;+++[U3KQD6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475785}; Flags: Fragment;+++[U3KQJ0_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475923}; Flags: Fragment;"]
[10199,"'MPHOSPH10'",378,346,349,357.666666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034457///Mpp10 complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006396///RNA processing+++GO:0042254///ribosome biogenesis+++GO:0010923///negative regulation of phosphatase activity+++GO:0006364///rRNA processing+++GO:0008380///RNA splicing","M-phase phosphoprotein 10","[MPP10_HUMAN|Reviewed]RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10; AltName: Full=M phase phosphoprotein 10;+++[U3KQ48_HUMAN|Unreviewed]SubName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000313|Ensembl:ENSP00000475545};"]
[102,"'ADAM10'",2011,1765,1869,1881.66666666667,"05010///Alzheimer's disease+++05120///Epithelial cell signaling in Helicobacter pylori infection",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0030425///dendrite+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0043025///neuronal cell body+++GO:0070062///extracellular exosome+++GO:0070821///tertiary granule membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0098794///postsynapse+++GO:0005798///Golgi-associated vesicle+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion","GO:0004222///metalloendopeptidase activity+++GO:0019901///protein kinase binding+++GO:0008233///peptidase activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0017124///SH3 domain binding+++GO:0008237///metallopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0008284///positive regulation of cell proliferation+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0034205///amyloid-beta formation+++GO:0030307///positive regulation of cell growth+++GO:0001701///in utero embryonic development+++GO:0007162///negative regulation of cell adhesion+++GO:0043687///post-translational protein modification+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0007219///Notch signaling pathway+++GO:0016485///protein processing+++GO:0051089///constitutive protein ectodomain proteolysis+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0034612///response to tumor necrosis factor+++GO:0007283///spermatogenesis+++GO:0022617///extracellular matrix disassembly+++GO:0051088///PMA-inducible membrane protein ectodomain proteolysis+++GO:0006508///proteolysis+++GO:0007267///cell-cell signaling+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0007229///integrin-mediated signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0097327///response to antineoplastic agent+++GO:0006468///protein phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0043312///neutrophil degranulation+++GO:0099173///postsynapse organization+++GO:0042117///monocyte activation+++GO:0035333///Notch receptor processing, ligand-dependent+++GO:0043065///positive regulation of apoptotic process","ADAM metallopeptidase domain 10","[ADA10_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; EC=3.4.24.81 {ECO:0000269|PubMed:11477090, ECO:0000269|PubMed:12475894, ECO:0000269|PubMed:16239146, ECO:0000269|PubMed:17557115, ECO:0000269|PubMed:19114711, ECO:0000269|PubMed:20592283, ECO:0000269|PubMed:29224781}; AltName: Full=CDw156; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: CD_antigen=CD156c; Flags: Precursor;+++[A0A024R5U5_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase domain 10, isoform CRA_b {ECO:0000313|EMBL:EAW77541.1};+++[A0A087WYG1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000481779};+++[A0AV88_HUMAN|Unreviewed]SubName: Full=ADAM10 protein {ECO:0000313|EMBL:AAI26254.1};+++[B5MC71_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000386056};+++[C9J9B4_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000391930}; Flags: Fragment;+++[H0YK32_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452639};+++[H0YK87_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452704}; Flags: Fragment;+++[H0YNC5_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000453952}; Flags: Fragment;+++[H3BS53_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000456542}; Flags: Fragment;+++[L8E9R5_HUMAN|Unreviewed]SubName: Full=Alternative protein ADAM10 {ECO:0000313|EMBL:CCQ43088.1};"]
[1020,"'CDK5'",388,406,371,388.333333333333,"05010///Alzheimer's disease+++05030///Cocaine addiction+++04360///Axon guidance","H00268///Lissencephaly (LIS)",null,null,"GO:0005874///microtubule+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0043204///perikaryon+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0098794///postsynapse+++GO:0030424///axon+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane+++GO:0016533///protein kinase 5 complex+++GO:0030425///dendrite+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse","GO:0016301///kinase activity+++GO:0043125///ErbB-3 class receptor binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0002039///p53 binding+++GO:0050321///tau-protein kinase activity+++GO:0000166///nucleotide binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels+++GO:0051879///Hsp90 protein binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0048156///tau protein binding+++GO:0046875///ephrin receptor binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0030549///acetylcholine receptor activator activity+++GO:0005176///ErbB-2 class receptor binding+++GO:0008017///microtubule binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016740///transferase activity","GO:0007399///nervous system development+++GO:0051402///neuron apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008542///visual learning+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0032801///receptor catabolic process+++GO:0000226///microtubule cytoskeleton organization+++GO:0045861///negative regulation of proteolysis+++GO:0098883///synapse pruning+++GO:0032092///positive regulation of protein binding+++GO:0008306///associative learning+++GO:2000273///positive regulation of signaling receptor activity+++GO:0048813///dendrite morphogenesis+++GO:0071156///regulation of cell cycle arrest+++GO:0022038///corpus callosum development+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0008045///motor neuron axon guidance+++GO:0016079///synaptic vesicle exocytosis+++GO:0042220///response to cocaine+++GO:0008283///cell proliferation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0009611///response to wounding+++GO:0048489///synaptic vesicle transport+++GO:0070509///calcium ion import+++GO:0048812///neuron projection morphogenesis+++GO:0021695///cerebellar cortex development+++GO:0016241///regulation of macroautophagy+++GO:1904646///cellular response to amyloid-beta+++GO:0006886///intracellular protein transport+++GO:0035418///protein localization to synapse+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0021766///hippocampus development+++GO:0045860///positive regulation of protein kinase activity+++GO:0034352///positive regulation of glial cell apoptotic process+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:0031397///negative regulation of protein ubiquitination+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0007049///cell cycle+++GO:0030182///neuron differentiation+++GO:0046826///negative regulation of protein export from nucleus+++GO:0016572///histone phosphorylation+++GO:0030900///forebrain development+++GO:0048167///regulation of synaptic plasticity+++GO:0031175///neuron projection development+++GO:0048148///behavioral response to cocaine+++GO:0035249///synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0045055///regulated exocytosis+++GO:0007409///axonogenesis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0042501///serine phosphorylation of STAT protein+++GO:0006915///apoptotic process+++GO:0051301///cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0019233///sensory perception of pain+++GO:0014044///Schwann cell development+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0021697///cerebellar cortex formation+++GO:0006913///nucleocytoplasmic transport+++GO:0007519///skeletal muscle tissue development+++GO:0007005///mitochondrion organization+++GO:0021537///telencephalon development+++GO:0045786///negative regulation of cell cycle+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0048709///oligodendrocyte differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007160///cell-matrix adhesion+++GO:0021987///cerebral cortex development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0021954///central nervous system neuron development+++GO:0021819///layer formation in cerebral cortex+++GO:0048675///axon extension+++GO:0043113///receptor clustering+++GO:0006468///protein phosphorylation+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0001764///neuron migration+++GO:0021549///cerebellum development+++GO:1903421///regulation of synaptic vesicle recycling+++GO:0001963///synaptic transmission, dopaminergic+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0016477///cell migration+++GO:0030517///negative regulation of axon extension+++GO:0048511///rhythmic process+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0007416///synapse assembly+++GO:0016310///phosphorylation","cyclin dependent kinase 5","[CDK5_HUMAN|Reviewed]RecName: Full=Cyclin-dependent-like kinase 5; EC=2.7.11.1; AltName: Full=Cell division protein kinase 5; AltName: Full=Serine/threonine-protein kinase PSSALRE; AltName: Full=Tau protein kinase II catalytic subunit; Short=TPKII catalytic subunit;+++[A0A090N7W4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 {ECO:0000313|EMBL:EAL24498.1}; SubName: Full=Cyclin-dependent kinase 5 isoform 1 {ECO:0000313|EMBL:ALQ33426.1}; SubName: Full=Cyclin-dependent kinase 5, isoform CRA_a {ECO:0000313|EMBL:EAW54049.1};+++[A0A0S2Z355_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 isoform 2 {ECO:0000313|EMBL:ALQ33427.1}; Flags: Fragment;+++[Q6IAW3_HUMAN|Unreviewed]SubName: Full=CDK5 protein {ECO:0000313|EMBL:CAG33322.1};"]
[10200,"'MPHOSPH6'",115,108,118,113.666666666667,"03018///RNA degradation",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0000178///exosome (RNase complex)+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0030165///PDZ domain binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0000460///maturation of 5.8S rRNA+++GO:0065003///protein-containing complex assembly","M-phase phosphoprotein 6","[MPH6_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 6 {ECO:0000305};+++[H3BNK8_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6, isoform CRA_b {ECO:0000313|EMBL:EAW95517.1};+++[H3BNT4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000454996};+++[H3BSB3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000456626};+++[H3BU96_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000457537};"]
[10201,"'NME6'",284,319.99,292,298.663333333333,"04016///MAPK signaling pathway - plant+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00230///Purine metabolism",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase   ATP + dCDP <=> ADP + dCTP+++R00124///ATP:ADP phosphatransferase   ATP + ADP <=> ADP + ATP+++R00156///ATP:UDP phosphotransferase   ATP + UDP <=> ADP + UTP+++R00330///ATP:GDP phosphotransferase   ATP + GDP <=> ADP + GTP+++R01857///ATP:dGDP phosphotransferase   ATP + dGDP <=> ADP + dGTP+++R00570///ATP:CDP phosphotransferase   ATP + CDP <=> ADP + CTP+++R11895///ATP:5-fluorodeoxyuridine-diphosphate phosphotransferase   ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate+++R01137///ATP:dADP phosphotransferase   ATP + dADP <=> ADP + dATP+++R02331///ATP:dUDP phosphotransferase   ATP + dUDP <=> ADP + dUTP+++R02093///ATP:dTDP phosphotransferase   ATP + dTDP <=> ADP + dTTP+++R00139///ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase   2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP+++R00722///ATP:IDP phosphotransferase   ATP + IDP <=> ADP + ITP+++R11894///ATP:5-fluorouridine-diphosphate phosphotransferase   ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate+++R03530///ATP:dIDP phosphotransferase   ATP + dIDP <=> ADP + dITP","GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0045839///negative regulation of mitotic nuclear division+++GO:0016310///phosphorylation+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0030308///negative regulation of cell growth+++GO:0006228///UTP biosynthetic process+++GO:0006915///apoptotic process","NME/NM23 nucleoside diphosphate kinase 6","[NDK6_HUMAN|Reviewed]RecName: Full=Nucleoside diphosphate kinase 6; Short=NDK 6; Short=NDP kinase 6; EC=2.7.4.6; AltName: Full=Inhibitor of p53-induced apoptosis-alpha; Short=IPIA-alpha; AltName: Full=nm23-H6;+++[A0A0C4DG91_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y547_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y7V2_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[C9J1J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000392715}; Flags: Fragment;+++[C9J867_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000405755}; Flags: Fragment;+++[C9J9V6_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013}; Flags: Fragment;+++[C9JQB1_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[F2Z2J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000410435};"]
[10202,"'DHRS2'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix","GO:0016491///oxidoreductase activity+++GO:0004090///carbonyl reductase (NADPH) activity+++GO:0005515///protein binding","GO:0008285///negative regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0009636///response to toxic substance+++GO:0055114///oxidation-reduction process+++GO:0043011///myeloid dendritic cell differentiation+++GO:0034599///cellular response to oxidative stress","dehydrogenase/reductase 2","[DHRS2_HUMAN|Reviewed]RecName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial; EC=1.1.1.-; AltName: Full=Dicarbonyl reductase HEP27; AltName: Full=Protein D; AltName: Full=Short chain dehydrogenase/reductase family 25C member 1; Flags: Precursor;+++[C9JZP6_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000401213}; Flags: Fragment;+++[H0YJG9_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451485}; Flags: Fragment;+++[H0YJP4_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451895}; Flags: Fragment;"]
[10203,"'CALCRL'",2,1,0,1,"04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:1990406///CGRP receptor complex+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:1903143///adrenomedullin receptor complex","GO:1990409///adrenomedullin binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0004930///G protein-coupled receptor activity+++GO:0001605///adrenomedullin receptor activity+++GO:0004948///calcitonin receptor activity","GO:0045986///negative regulation of smooth muscle contraction+++GO:0007507///heart development+++GO:0001525///angiogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0031623///receptor internalization+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0006816///calcium ion transport+++GO:0015031///protein transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway+++GO:0071329///cellular response to sucrose stimulus+++GO:0050728///negative regulation of inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","calcitonin receptor like receptor","[CALRL_HUMAN|Reviewed]RecName: Full=Calcitonin gene-related peptide type 1 receptor; Short=CGRP type 1 receptor; AltName: Full=Calcitonin receptor-like receptor; Flags: Precursor;+++[B8ZZJ4_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000386599}; Flags: Fragment;+++[D3DPG9_HUMAN|Unreviewed]SubName: Full=Calcitonin receptor-like, isoform CRA_a {ECO:0000313|EMBL:EAX10926.1};+++[E7EN01_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000415626}; Flags: Fragment;"]
[10204,"'NUTF2'",3086,2641,2753,2826.66666666667,{"$nulls":4},"GO:0044613///nuclear pore central transport channel+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0005637///nuclear inner membrane+++GO:0005643///nuclear pore+++GO:0005640///nuclear outer membrane","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0017056///structural constituent of nuclear pore","GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0042307///positive regulation of protein import into nucleus+++GO:0090204///protein localization to nuclear pore+++GO:1904046///negative regulation of vascular endothelial growth factor production+++GO:0015031///protein transport+++GO:0000060///protein import into nucleus, translocation+++GO:0006913///nucleocytoplasmic transport","nuclear transport factor 2","[NTF2_HUMAN|Reviewed]RecName: Full=Nuclear transport factor 2 {ECO:0000303|PubMed:7744965}; Short=NTF-2; AltName: Full=Placental protein 15 {ECO:0000303|PubMed:3380696}; Short=PP15 {ECO:0000303|PubMed:3380696};+++[A0A024R6Y2_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2, isoform CRA_a {ECO:0000313|EMBL:EAW83182.1};+++[H3BRV9_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2 {ECO:0000313|Ensembl:ENSP00000456428}; Flags: Fragment;"]
[10205,"'MPZL2'",6,3,4,4.33333333333333,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0009653///anatomical structure morphogenesis+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","myelin protein zero like 2","[MPZL2_HUMAN|Reviewed]RecName: Full=Myelin protein zero-like protein 2; AltName: Full=Epithelial V-like antigen 1; Flags: Precursor;+++[A0A024R3K1_HUMAN|Unreviewed]SubName: Full=Epithelial V-like antigen 1, isoform CRA_a {ECO:0000313|EMBL:EAW67359.1};"]
[10206,"'TRIM13'",278.47,207.53,241.93,242.643333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0005737///cytoplasm+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:1902187///negative regulation of viral release from host cell+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0010332///response to gamma radiation+++GO:0016239///positive regulation of macroautophagy+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0002376///immune system process+++GO:0051865///protein autoubiquitination+++GO:0009653///anatomical structure morphogenesis+++GO:0010942///positive regulation of cell death+++GO:0016567///protein ubiquitination+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0045087///innate immune response+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:0032897///negative regulation of viral transcription","tripartite motif containing 13","[TRI13_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM13; EC=2.3.2.27; AltName: Full=B-cell chronic lymphocytic leukemia tumor suppressor Leu5; AltName: Full=Leukemia-associated protein 5; AltName: Full=Putative tumor suppressor RFP2; AltName: Full=RING finger protein 77; AltName: Full=RING-type E3 ubiquitin transferase TRIM13 {ECO:0000305}; AltName: Full=Ret finger protein 2; AltName: Full=Tripartite motif-containing protein 13;+++[A0A024RDU3_HUMAN|Unreviewed]SubName: Full=Ret finger protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX08848.1};+++[A0A184AP76_HUMAN|Unreviewed]SubName: Full=Putative tumor suppressor RFP2 {ECO:0000313|EMBL:ABE41638.1};+++[L7MTJ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAD38633.1}; Flags: Fragment;+++[L8E9D0_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM13 {ECO:0000313|EMBL:CCQ43336.1};+++[X6R9U5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000367425}; Flags: Fragment;+++[X6RH27_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000404586}; Flags: Fragment;"]
[10207,"'PATJ'",288.4,294,274,285.466666666667,"04390///Hippo signaling pathway+++05165///Human papillomavirus infection+++04530///Tight junction",{"$nulls":3},"GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0045177///apical part of cell+++GO:0032991///protein-containing complex+++GO:0005923///bicellular tight junction+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0035556///intracellular signal transduction+++GO:0070830///bicellular tight junction assembly","PATJ, crumbs cell polarity complex component","[INADL_HUMAN|Reviewed]RecName: Full=InaD-like protein; Short=Inadl protein; Short=hINADL; AltName: Full=Pals1-associated tight junction protein; AltName: Full=Protein associated to tight junctions;+++[A0A087WUZ6_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000479041};+++[A0A0U1RQR3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489130}; Flags: Fragment;+++[A0A0U1RQT2_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489159};+++[A0A0U1RQW4_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489200}; Flags: Fragment;+++[A0A0U1RR46_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489335};+++[A0A0U1RRD7_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489475}; Flags: Fragment;+++[A0A0X1KG69_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000326199};+++[A0A2R8Y549_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494277};+++[A0A2R8Y5I3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494824};+++[A5PKX9_HUMAN|Unreviewed]SubName: Full=INADL protein {ECO:0000313|EMBL:AAI42662.1};+++[B4DE90_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59473, highly similar to InaD-like protein {ECO:0000313|EMBL:BAG57001.1};"]
[10208,"'USPL1'",199,183,205,195.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0070140///SUMO-specific isopeptidase activity+++GO:0043130///ubiquitin binding","GO:0030576///Cajal body organization+++GO:0009301///snRNA transcription+++GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0008283///cell proliferation","ubiquitin specific peptidase like 1","[USPL1_HUMAN|Reviewed]RecName: Full=SUMO-specific isopeptidase USPL1; EC=3.4.22.-; AltName: Full=Ubiquitin-specific peptidase-like protein 1; Short=USP-like 1;+++[A8K1B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75211, highly similar to Homo sapiens ubiquitin specific peptidase like 1, mRNA {ECO:0000313|EMBL:BAF82515.1};+++[B3KQ64_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32952 fis, clone TESTI2008081, highly similar to Homo sapiens D13S106 a highly charged amino acid sequence {ECO:0000313|EMBL:BAG51926.1}; Flags: Fragment;+++[L8ECC7_HUMAN|Unreviewed]SubName: Full=Alternative protein USPL1 {ECO:0000313|EMBL:CCQ43337.1};"]
[10209,"'EIF1'",3204,2960,2768,2977.33333333333,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding","GO:0006412///translation+++GO:0006446///regulation of translational initiation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0006413///translational initiation","eukaryotic translation initiation factor 1","[EIF1_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1; Short=eIF1; AltName: Full=A121; AltName: Full=Protein translation factor SUI1 homolog; AltName: Full=Sui1iso1;+++[K7EM18_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000466321};+++[K7EQP2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000467918}; Flags: Fragment;+++[Q6IAV3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW60754.1}; SubName: Full=Putative translation initiation factor {ECO:0000313|EMBL:AAP35291.1}; SubName: Full=SUI1 protein {ECO:0000313|EMBL:CAG33332.1}; SubName: Full=cDNA, FLJ92128, Homo sapiens putative translation initiation factor (SUI1), mRNA {ECO:0000313|EMBL:BAG34803.1};"]
[1021,"'CDK6'",1849,1679,1714,1747.33333333333,"05218///Melanoma+++05224///Breast cancer+++04110///Cell cycle+++05200///Pathways in cancer+++05214///Glioma+++04218///Cellular senescence+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05162///Measles+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04151///PI3K-Akt signaling pathway+++05223///Non-small cell lung cancer+++05163///Human cytomegalovirus infection+++04934///Cushing's syndrome+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++05161///Hepatitis B+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++05212///Pancreatic cancer","H00269///Primary microcephaly (MCPH)","M00692///Cell cycle - G1/S transition",null,"GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0001726///ruffle+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0098770///FBXO family protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0030332///cyclin binding+++GO:0016740///transferase activity","GO:0050680///negative regulation of epithelial cell proliferation+++GO:0043697///cell dedifferentiation+++GO:0007049///cell cycle+++GO:0048699///generation of neurons+++GO:0045668///negative regulation of osteoblast differentiation+++GO:2000145///regulation of cell motility+++GO:0045656///negative regulation of monocyte differentiation+++GO:0014002///astrocyte development+++GO:0003323///type B pancreatic cell development+++GO:0009615///response to virus+++GO:0051301///cell division+++GO:0042063///gliogenesis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0021670///lateral ventricle development+++GO:0045596///negative regulation of cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0006468///protein phosphorylation+++GO:0045646///regulation of erythrocyte differentiation+++GO:0030154///cell differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0021542///dentate gyrus development+++GO:0010468///regulation of gene expression+++GO:0045786///negative regulation of cell cycle+++GO:0007050///cell cycle arrest","cyclin dependent kinase 6","[CDK6_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 6; EC=2.7.11.22; AltName: Full=Cell division protein kinase 6; AltName: Full=Serine/threonine-protein kinase PLSTIRE;"]
[10210,"'TOPORS'",482,463,437,460.666666666667,null,"H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005814///centriole+++GO:0000151///ubiquitin ligase complex+++GO:0000930///gamma-tubulin complex+++GO:0030496///midbody+++GO:0032391///photoreceptor connecting cilium+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005868///cytoplasmic dynein complex+++GO:0036064///ciliary basal body+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0019789///SUMO transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0044547///DNA topoisomerase binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003823///antigen binding","GO:0000209///protein polyubiquitination+++GO:0034504///protein localization to nucleus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006351///transcription, DNA-templated+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0042127///regulation of cell proliferation+++GO:0016925///protein sumoylation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0010842///retina layer formation+++GO:0046548///retinal rod cell development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0035845///photoreceptor cell outer segment organization+++GO:0051457///maintenance of protein location in nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0046549///retinal cone cell development+++GO:0006513///protein monoubiquitination","TOP1 binding arginine/serine rich protein","[TOPRS_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Topors; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase Topors {ECO:0000305}; AltName: Full=SUMO1-protein E3 ligase Topors; AltName: Full=Topoisomerase I-binding RING finger protein; AltName: Full=Topoisomerase I-binding arginine/serine-rich protein; AltName: Full=Tumor suppressor p53-binding protein 3; Short=p53-binding protein 3; Short=p53BP3;"]
[10211,"'FLOT1'",1626,1687,1342,1551.66666666667,"04910///Insulin signaling pathway",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0044853///plasma membrane raft+++GO:0042383///sarcolemma+++GO:0016600///flotillin complex+++GO:0005815///microtubule organizing center+++GO:0048786///presynaptic active zone+++GO:0005765///lysosomal membrane+++GO:0098793///presynapse+++GO:0042470///melanosome+++GO:0030027///lamellipodium+++GO:0005768///endosome+++GO:0045121///membrane raft+++GO:0005913///cell-cell adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0044291///cell-cell contact zone+++GO:0098978///glutamatergic synapse+++GO:0005901///caveola+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0001931///uropod+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0098982///GABA-ergic synapse+++GO:0016324///apical plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0008180///COP9 signalosome+++GO:0098691///dopaminergic synapse+++GO:0034451///centriolar satellite+++GO:0030864///cortical actin cytoskeleton+++GO:0005769///early endosome","GO:0046982///protein heterodimerization activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0002020///protease binding+++GO:0005515///protein binding","GO:1903044///protein localization to membrane raft+++GO:0032728///positive regulation of interferon-beta production+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0001765///membrane raft assembly+++GO:1901890///positive regulation of cell junction assembly+++GO:0022617///extracellular matrix disassembly+++GO:0051580///regulation of neurotransmitter uptake+++GO:0070528///protein kinase C signaling+++GO:0007409///axonogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0050821///protein stabilization+++GO:1901741///positive regulation of myoblast fusion+++GO:0051260///protein homooligomerization+++GO:0044854///plasma membrane raft assembly+++GO:0034976///response to endoplasmic reticulum stress+++GO:0033227///dsRNA transport+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0002090///regulation of receptor internalization+++GO:0045807///positive regulation of endocytosis+++GO:0035023///regulation of Rho protein signal transduction+++GO:0001819///positive regulation of cytokine production+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034143///regulation of toll-like receptor 4 signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071360///cellular response to exogenous dsRNA+++GO:0032226///positive regulation of synaptic transmission, dopaminergic","flotillin 1","[FLOT1_HUMAN|Reviewed]RecName: Full=Flotillin-1;+++[A0A0G2JJQ6_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000409995}; Flags: Fragment;+++[A0A140T905_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388153}; Flags: Fragment;+++[A0A140T907_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388104}; Flags: Fragment;+++[A0A140T910_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388517}; Flags: Fragment;+++[A0A140T957_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393145}; Flags: Fragment;+++[A0A140T959_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000392736}; Flags: Fragment;+++[A0A140T974_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393767}; Flags: Fragment;+++[A0A140T9B1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000397108}; Flags: Fragment;+++[A0A140T9C3_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398866}; Flags: Fragment;+++[A0A140T9H7_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000403574}; Flags: Fragment;+++[A0A140T9L9_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000407101}; Flags: Fragment;+++[A0A140T9R1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000410658}; Flags: Fragment;+++[A0A140T9W4_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415215}; Flags: Fragment;+++[A0A140T9X0_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415104}; Flags: Fragment;+++[A2AB09_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000395333}; Flags: Fragment;+++[A2AB10_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000400615}; Flags: Fragment;+++[A2AB11_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000412058}; Flags: Fragment;+++[A2AB12_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398834}; Flags: Fragment;+++[A2AB13_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000391341}; Flags: Fragment;+++[A2ABJ5_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000404300}; Flags: Fragment;+++[A2VCL5_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:AAI28155.1}; Flags: Fragment;+++[Q5ST80_HUMAN|Unreviewed]SubName: Full=FLOT1 {ECO:0000313|EMBL:AQY76816.1}; SubName: Full=FLOT1 protein {ECO:0000313|EMBL:BAF31269.1}; SubName: Full=Flotillin 1 {ECO:0000313|EMBL:AAP35740.1}; SubName: Full=Flotillin 1, isoform CRA_b {ECO:0000313|EMBL:EAX03326.1};+++[Q6IB58_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:CAG33227.1};"]
[10212,"'DDX39A'",341,269,290,300,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing","DExD-box helicase 39A","[DX39A_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX39A; EC=3.6.4.13; AltName: Full=DEAD box protein 39; AltName: Full=Nuclear RNA helicase URH49;+++[A0A024R7H0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, isoform CRA_b {ECO:0000313|EMBL:EAW84416.1};+++[A0A0D9SEM9_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000485838}; Flags: Fragment;+++[K7EIL8_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000464801}; Flags: Fragment;+++[K7EL56_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000465926}; Flags: Fragment;+++[K7EN69_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000466810}; Flags: Fragment;+++[K7ENP6_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467040}; Flags: Fragment;+++[K7EPJ3_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467411}; Flags: Fragment;+++[K7EQN7_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467911}; Flags: Fragment;"]
[10213,"'PSMD14'",464,453,468,461.666666666667,"05169///Epstein-Barr virus infection+++03050///Proteasome",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0031597///cytosolic proteasome complex+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0000502///proteasome complex+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0034774///secretory granule lumen+++GO:0005634///nucleus+++GO:0022624///proteasome accessory complex+++GO:1904813///ficolin-1-rich granule lumen","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0061133///endopeptidase activator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070628///proteasome binding+++GO:0016787///hydrolase activity","GO:0006281///DNA repair+++GO:0043312///neutrophil degranulation+++GO:0070536///protein K63-linked deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010950///positive regulation of endopeptidase activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006508///proteolysis+++GO:0000724///double-strand break repair via homologous recombination+++GO:0043687///post-translational protein modification+++GO:0045471///response to ethanol+++GO:0016579///protein deubiquitination+++GO:0061136///regulation of proteasomal protein catabolic process","proteasome 26S subunit, non-ATPase 14","[PSDE_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 14; EC=3.4.19.-; AltName: Full=26S proteasome regulatory subunit RPN11; AltName: Full=26S proteasome-associated PAD1 homolog 1;+++[A0A140VKF2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 69n {ECO:0000313|EMBL:AEE61289.1};+++[C9JW37_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 14 {ECO:0000313|Ensembl:ENSP00000399311}; Flags: Fragment;+++[Q4ZG77_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAX88940.1}; Flags: Fragment;+++[Q53TH1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAY15016.1}; Flags: Fragment;"]
[102157402,"'AK6'",65.74,65.62,51.09,60.8166666666667,"00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03008///Ribosome biogenesis in eukaryotes",null,"M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R00127///ATP:AMP phosphotransferase   ATP + AMP <=> 2 ADP+++R01547///ATP:dAMP phosphotransferase   ATP + dAMP <=> ADP + dADP","GO:0000790///nuclear chromatin+++GO:0005669///transcription factor TFIID complex+++GO:0031389///Rad17 RFC-like complex+++GO:0005737///cytoplasm+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000125///PCAF complex+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003713///transcription coactivator activity+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005524///ATP binding+++GO:0033613///activating transcription factor binding+++GO:0051117///ATPase binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0003689///DNA clamp loader activity+++GO:0003682///chromatin binding+++GO:0050145///nucleoside monophosphate kinase activity+++GO:0004017///adenylate kinase activity+++GO:0016887///ATPase activity","GO:0030307///positive regulation of cell growth+++GO:0043966///histone H3 acetylation+++GO:0033314///mitotic DNA replication checkpoint+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008156///negative regulation of DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000492///box C/D snoRNP assembly+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0000077///DNA damage checkpoint+++GO:0006366///transcription by RNA polymerase II+++GO:0042325///regulation of phosphorylation+++GO:0050821///protein stabilization+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0070555///response to interleukin-1+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0043066///negative regulation of apoptotic process+++GO:0006260///DNA replication+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0000076///DNA replication checkpoint+++GO:0007093///mitotic cell cycle checkpoint","adenylate kinase 6","[KAD6_HUMAN|Reviewed]RecName: Full=Adenylate kinase isoenzyme 6 {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK6 {ECO:0000255|HAMAP-Rule:MF_03173}; EC=2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03173}; AltName: Full=Adrenal gland protein AD-004; AltName: Full=Coilin-interacting nuclear ATPase protein {ECO:0000255|HAMAP-Rule:MF_03173}; Short=hCINAP; AltName: Full=Dual activity adenylate kinase/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK/ATPase {ECO:0000255|HAMAP-Rule:MF_03173};+++[A0A087WVD7_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000479366};+++[A0A087WY94_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000481620};+++[D6RDH4_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000420947};"]
[10216,"'PRG4'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0062023///collagen-containing extracellular matrix","GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0030247///polysaccharide binding+++GO:0005044///scavenger receptor activity","GO:0008283///cell proliferation+++GO:0006955///immune response","proteoglycan 4","[PRG4_HUMAN|Reviewed]RecName: Full=Proteoglycan 4; AltName: Full=Lubricin; AltName: Full=Megakaryocyte-stimulating factor; AltName: Full=Superficial zone proteoglycan; Contains: RecName: Full=Proteoglycan 4 C-terminal part; Flags: Precursor;+++[A0A0U1RR20_HUMAN|Unreviewed]SubName: Full=Proteoglycan 4 {ECO:0000313|Ensembl:ENSP00000489292};"]
[10217,"'CTDSPL'",437,556,452,481.666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0016787///hydrolase activity","GO:0016311///dephosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0008150///biological_process","CTD small phosphatase like","[CTDSL_HUMAN|Reviewed]RecName: Full=CTD small phosphatase-like protein; Short=CTDSP-like; EC=3.1.3.16; AltName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; AltName: Full=NIF-like protein; AltName: Full=Nuclear LIM interactor-interacting factor 1; Short=NLI-interacting factor 1; AltName: Full=Protein YA22; Short=hYA22; AltName: Full=RBSP3; AltName: Full=Small C-terminal domain phosphatase 3; Short=SCP3; Short=Small CTD phosphatase 3;+++[A0A024R2L8_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, isoform CRA_c {ECO:0000313|EMBL:EAW64505.1};+++[F8WED2_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000408183};+++[H7C2B9_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000404977}; Flags: Fragment;+++[H7C2S4_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000407443}; Flags: Fragment;+++[H7C353_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000409600}; Flags: Fragment;"]
[10218,"'ANGPTL7'",902,685,635,740.666666666667,{"$nulls":4},"GO:0005576///extracellular region","GO:0005515///protein binding","GO:0006979///response to oxidative stress","angiopoietin like 7","[ANGL7_HUMAN|Reviewed]RecName: Full=Angiopoietin-related protein 7; AltName: Full=Angiopoietin-like factor; AltName: Full=Angiopoietin-like protein 7; AltName: Full=Cornea-derived transcript 6 protein; Flags: Precursor;"]
[10219,"'KLRG1'",1,5,4,3.33333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0030246///carbohydrate binding+++GO:0042803///protein homodimerization activity+++GO:0038023///signaling receptor activity","GO:0007263///nitric oxide mediated signal transduction+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045087///innate immune response+++GO:0002376///immune system process+++GO:0009749///response to glucose+++GO:0007166///cell surface receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006968///cellular defense response+++GO:0006954///inflammatory response+++GO:0030073///insulin secretion","killer cell lectin like receptor G1","[KLRG1_HUMAN|Reviewed]RecName: Full=Killer cell lectin-like receptor subfamily G member 1; AltName: Full=C-type lectin domain family 15 member A; AltName: Full=ITIM-containing receptor MAFA-L; AltName: Full=MAFA-like receptor; AltName: Full=Mast cell function-associated antigen;+++[F5H207_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily G member 1 {ECO:0000313|Ensembl:ENSP00000445627}; Flags: Fragment;+++[F5H8E3_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily G member 1 {ECO:0000313|Ensembl:ENSP00000443658}; Flags: Fragment;"]
[1022,"'CDK7'",265,189,202,218.666666666667,"04110///Cell cycle+++03022///Basal transcription factors+++03420///Nucleotide excision repair",null,"M00290///Holo-TFIIH complex",null,"GO:0070985///transcription factor TFIIK complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0003713///transcription coactivator activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0050681///androgen receptor binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008022///protein C-terminus binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0007050///cell cycle arrest+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007049///cell cycle+++GO:0030521///androgen receptor signaling pathway+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0008283///cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0050821///protein stabilization+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006370///7-methylguanosine mRNA capping+++GO:0006468///protein phosphorylation+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016310///phosphorylation+++GO:0006363///termination of RNA polymerase I transcription","cyclin dependent kinase 7","[CDK7_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 7; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=39 kDa protein kinase; Short=p39 Mo15; AltName: Full=CDK-activating kinase 1; AltName: Full=Cell division protein kinase 7; AltName: Full=Serine/threonine-protein kinase 1; AltName: Full=TFIIH basal transcription factor complex kinase subunit;+++[A0A0S2Z3F9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), isoform CRA_a {ECO:0000313|EMBL:EAW51300.1}; SubName: Full=Cyclin-dependent kinase 7 isoform 1 {ECO:0000313|EMBL:ALQ33428.1}; Flags: Fragment;+++[D6R9G1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422121};+++[D6R9Z2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422027};+++[D6RAD4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422737};+++[D6REC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425043}; Flags: Fragment;+++[D6RF14_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000421559};+++[D6RFL0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 isoform 3 {ECO:0000313|EMBL:ALQ33429.1};+++[D6RGG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000426372};+++[D6RI01_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425983};+++[D6RIG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425893};+++[Q14495_HUMAN|Unreviewed]SubName: Full=Protein kinase {ECO:0000313|EMBL:CAA53766.1}; Flags: Fragment;"]
[10220,"'GDF11'",2010,2995,2327,2444,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005575///cellular_component+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity","GO:0060021///roof of mouth development+++GO:0007399///nervous system development+++GO:0048593///camera-type eye morphogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0048468///cell development+++GO:0008285///negative regulation of cell proliferation+++GO:0060395///SMAD protein signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010469///regulation of signaling receptor activity+++GO:0043408///regulation of MAPK cascade+++GO:0001501///skeletal system development+++GO:0031016///pancreas development+++GO:0007498///mesoderm development+++GO:0001656///metanephros development+++GO:0021512///spinal cord anterior/posterior patterning+++GO:0048469///cell maturation+++GO:0042981///regulation of apoptotic process+++GO:0009887///animal organ morphogenesis+++GO:0001657///ureteric bud development+++GO:0009952///anterior/posterior pattern specification+++GO:0045596///negative regulation of cell differentiation","growth differentiation factor 11","[GDF11_HUMAN|Reviewed]RecName: Full=Growth/differentiation factor 11 {ECO:0000303|PubMed:10391213}; Short=GDF-11; AltName: Full=Bone morphogenetic protein 11 {ECO:0000303|PubMed:10075854}; Short=BMP-11; Flags: Precursor;+++[A0A024RB20_HUMAN|Unreviewed]SubName: Full=Growth differentiation factor 11, isoform CRA_a {ECO:0000313|EMBL:EAW96831.1};+++[H0YI30_HUMAN|Unreviewed]SubName: Full=Growth/differentiation factor 11 {ECO:0000313|Ensembl:ENSP00000448390}; Flags: Fragment;"]
[10221,"'TRIB1'",442,484,492,472.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004860///protein kinase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0055106///ubiquitin-protein transferase regulator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0005524///ATP binding","GO:0006469///negative regulation of protein kinase activity+++GO:0006468///protein phosphorylation+++GO:0045659///negative regulation of neutrophil differentiation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043405///regulation of MAP kinase activity+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0007254///JNK cascade+++GO:0032496///response to lipopolysaccharide+++GO:0045645///positive regulation of eosinophil differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0045651///positive regulation of macrophage differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation","tribbles pseudokinase 1","[TRIB1_HUMAN|Reviewed]RecName: Full=Tribbles homolog 1; Short=TRB-1; AltName: Full=G-protein-coupled receptor-induced gene 2 protein; Short=GIG-2; AltName: Full=SKIP1;+++[E5RFH4_HUMAN|Unreviewed]SubName: Full=Tribbles homolog 1 {ECO:0000313|Ensembl:ENSP00000428879};"]
[10223,"'GPA33'",4,7,3,4.66666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0038023///signaling receptor activity",null,"glycoprotein A33","[GPA33_HUMAN|Reviewed]RecName: Full=Cell surface A33 antigen; AltName: Full=Glycoprotein A33; Flags: Precursor;+++[A0A0J9YXH7_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000488407}; Flags: Fragment;+++[E9PMB2_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000431195};"]
[10224,"'ZNF443'",22.7,13.3,23,19.6666666666667,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 443","[ZN443_HUMAN|Reviewed]RecName: Full=Zinc finger protein 443; AltName: Full=Krueppel-type zinc finger protein ZK1;+++[F8WDY2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 443 {ECO:0000313|Ensembl:ENSP00000389105};"]
[10225,"'CD96'",7.35,10.24,16.99,11.5266666666667,null,"H01008///C syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm+++GO:0005912///adherens junction+++GO:0005886///plasma membrane",null,"GO:0007160///cell-matrix adhesion+++GO:0002728///negative regulation of natural killer cell cytokine production+++GO:0006955///immune response+++GO:0032496///response to lipopolysaccharide+++GO:0002534///cytokine production involved in inflammatory response+++GO:0007155///cell adhesion+++GO:0032689///negative regulation of interferon-gamma production+++GO:0050776///regulation of immune response","CD96 molecule","[TACT_HUMAN|Reviewed]RecName: Full=T-cell surface protein tactile; AltName: Full=Cell surface antigen CD96; AltName: Full=T cell-activated increased late expression protein; AltName: CD_antigen=CD96; Flags: Precursor;+++[E9PEJ1_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417152};+++[F8WDV3_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417680};+++[H7C4F0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417150}; Flags: Fragment;+++[L8EAH0_HUMAN|Unreviewed]SubName: Full=Alternative protein CD96 {ECO:0000313|EMBL:CCQ43338.1};+++[Q8WUE2_HUMAN|Unreviewed]SubName: Full=CD96 antigen, isoform CRA_b {ECO:0000313|EMBL:EAW79697.1}; SubName: Full=CD96 protein {ECO:0000313|EMBL:AAH20749.1}; SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000389801};+++[U3KPT0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000475194}; Flags: Fragment;"]
[10226,"'PLIN3'",1124,1158,1061,1114.33333333333,{"$nulls":4},"GO:0010008///endosome membrane+++GO:0030133///transport vesicle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005768///endosome","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0016192///vesicle-mediated transport","perilipin 3","[PLIN3_HUMAN|Reviewed]RecName: Full=Perilipin-3; AltName: Full=47 kDa mannose 6-phosphate receptor-binding protein; Short=47 kDa MPR-binding protein; AltName: Full=Cargo selection protein TIP47; AltName: Full=Mannose-6-phosphate receptor-binding protein 1; AltName: Full=Placental protein 17; Short=PP17;+++[A0A140VJN8_HUMAN|Unreviewed]RecName: Full=Perilipin {ECO:0000256|PIRNR:PIRNR036881};+++[K7EJD0_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465117}; Flags: Fragment;+++[K7EL96_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465975}; Flags: Fragment;+++[K7ER39_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468096}; Flags: Fragment;+++[K7ERZ3_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468476}; Flags: Fragment;"]
[10227,"'MFSD10'",1561,1409,1440,1470,{"$nulls":4},"GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016021///integral component of membrane","GO:0008514///organic anion transmembrane transporter activity+++GO:0008493///tetracycline transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006915///apoptotic process+++GO:0043252///sodium-independent organic anion transport+++GO:0015904///tetracycline transport","major facilitator superfamily domain containing 10","[MFS10_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 10; AltName: Full=Tetracycline transporter-like protein;+++[D6R9N3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423509};+++[D6RA47_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423402};+++[D6RE79_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000426907};+++[D6RHV1_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000427637};+++[D6RIZ4_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000425757};"]
[10228,"'STX6'",590,587,561,579.333333333333,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0000139///Golgi membrane+++GO:0005769///early endosome+++GO:0030136///clathrin-coated vesicle+++GO:0005654///nucleoplasm+++GO:0032588///trans-Golgi network membrane+++GO:0045335///phagocytic vesicle+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0008021///synaptic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0031201///SNARE complex","GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0016192///vesicle-mediated transport+++GO:0032880///regulation of protein localization+++GO:0048278///vesicle docking+++GO:0032456///endocytic recycling+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0006906///vesicle fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048193///Golgi vesicle transport+++GO:0090161///Golgi ribbon formation+++GO:0007032///endosome organization+++GO:1903827///regulation of cellular protein localization+++GO:0016189///synaptic vesicle to endosome fusion","syntaxin 6","[STX6_HUMAN|Reviewed]RecName: Full=Syntaxin-6;"]
[102288414,"'C11orf98'",591.77,532.84,526.73,550.446666666667,{"$nulls":7},"chromosome 11 open reading frame 98","[CK098_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf98 {ECO:0000305};+++[A0A0B4J220_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 48, isoform CRA_c {ECO:0000313|EMBL:EAW74054.1};+++[L0R588_HUMAN|Unreviewed]SubName: Full=Alternative protein C11orf48 {ECO:0000313|EMBL:CCO13689.1};"]
[10229,"'COQ7'",240,240,233,237.666666666667,"01100///Metabolic pathways+++00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01110///Biosynthesis of secondary metabolites","H00999///Coenzyme Q10 deficiency","M00128///Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone","R08775///2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O+++R04984///2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O","GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008682///2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity+++GO:0004497///monooxygenase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008340///determination of adult lifespan+++GO:0006744///ubiquinone biosynthetic process+++GO:0042493///response to drug+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0055114///oxidation-reduction process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000377///regulation of reactive oxygen species metabolic process","coenzyme Q7, hydroxylase","[COQ7_HUMAN|Reviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000255|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000255|HAMAP-Rule:MF_03194}; Flags: Precursor;+++[H3BP28_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[H3BS11_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456490};+++[H3BSZ3_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456943}; Flags: Fragment;+++[H3BTN8_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457256}; Flags: Fragment;+++[I3L1T0_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000459076}; SubName: Full=Coenzyme Q7 homolog, ubiquinone (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW50269.1};+++[Q49A71_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[Q8NI45_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};"]
[10231,"'RCAN2'",336,332,312,326.666666666667,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity+++GO:0005515///protein binding","GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0019722///calcium-mediated signaling","regulator of calcineurin 2","[RCAN2_HUMAN|Reviewed]RecName: Full=Calcipressin-2; AltName: Full=Down syndrome candidate region 1-like 1; AltName: Full=Myocyte-enriched calcineurin-interacting protein 2; Short=MCIP2; AltName: Full=Regulator of calcineurin 2; AltName: Full=Thyroid hormone-responsive protein ZAKI-4;+++[A0A0A0MSB6_HUMAN|Unreviewed]SubName: Full=Calcipressin-2 {ECO:0000313|Ensembl:ENSP00000384317};+++[A8MXP8_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000378347};+++[B2R612_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92723, highly similar to Homo sapiens Down syndrome critical region gene 1-like 1 (DSCR1L1), mRNA {ECO:0000313|EMBL:BAG35309.1};+++[H0YL43_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000453052}; Flags: Fragment;+++[L0R6N1_HUMAN|Unreviewed]SubName: Full=Alternative protein RCAN2 {ECO:0000313|EMBL:CCO13800.1};+++[L8E7F0_HUMAN|Unreviewed]SubName: Full=Alternative protein RCN2 {ECO:0000313|EMBL:CCQ43195.1};+++[Q86YJ0_HUMAN|Unreviewed]SubName: Full=RCAN2 protein {ECO:0000313|EMBL:AAH38509.1};"]
[10232,"'MSLN'",192,160,174,175.333333333333,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0044267///cellular protein metabolic process+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0031016///pancreas development+++GO:0043687///post-translational protein modification","mesothelin","[MSLN_HUMAN|Reviewed]RecName: Full=Mesothelin; AltName: Full=CAK1 antigen; AltName: Full=Pre-pro-megakaryocyte-potentiating factor; Contains: RecName: Full=Megakaryocyte-potentiating factor; Short=MPF; Contains: RecName: Full=Mesothelin, cleaved form; Flags: Precursor;+++[H3BMA1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000454295}; Flags: Fragment;+++[H3BR90_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000456132}; Flags: Fragment;+++[H3BUX1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000457847}; Flags: Fragment;+++[H3BV92_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000458003}; Flags: Fragment;"]
[10233,"'LRRC23'",189,162,126,159,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","leucine rich repeat containing 23","[LRC23_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 23; AltName: Full=Leucine-rich protein B7;+++[A8K8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77436, highly similar to Homo sapiens B7 gene (B7), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF85056.1};+++[C9JEW3_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000396049};+++[C9JKE8_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000402554};+++[C9JQN5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000408066}; Flags: Fragment;+++[E9PDZ4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000397192};+++[F2Z299_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000392623};"]
[10234,"'LRRC17'",479,398,606,494.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space",null,"GO:0033687///osteoblast proliferation+++GO:0048539///bone marrow development+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0001649///osteoblast differentiation+++GO:0001503///ossification","leucine rich repeat containing 17","[LRC17_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 17; AltName: Full=p37NB; Flags: Precursor;+++[C9JT74_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 17 {ECO:0000313|Ensembl:ENSP00000394194}; Flags: Fragment;"]
[10235,"'RASGRP2'",27,18,18,21,"04062///Chemokine signaling pathway+++04015///Rap1 signaling pathway+++04010///MAPK signaling pathway+++05200///Pathways in cancer+++04014///Ras signaling pathway+++04611///Platelet activation","H01235///Bleeding disorder platelet-type",null,null,"GO:0043005///neuron projection+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0008289///lipid binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0001558///regulation of cell growth+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0071277///cellular response to calcium ion","RAS guanyl releasing protein 2","[GRP2_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 2; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor I; Short=CalDAG-GEFI; AltName: Full=Cdc25-like protein; Short=hCDC25L; AltName: Full=F25B3.3 kinase-like protein;+++[A6NHE2_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366705}; Flags: Fragment;+++[A6NJ28_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366706};+++[A8MTF9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377950};+++[A8MVK8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377949};+++[B3KV60_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16161 fis, clone BRCAN2012110, highly similar to Homo sapiens RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53672.1};+++[C9JKH6_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000389068}; Flags: Fragment;+++[C9JZ82_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000401314}; Flags: Fragment;+++[E7EM78_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399114}; Flags: Fragment;+++[E7EMB4_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399028};+++[E7EWQ7_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000396029};+++[Q2YDB1_HUMAN|Unreviewed]SubName: Full=RASGRP2 protein {ECO:0000313|EMBL:AAI10307.1}; Flags: Fragment;"]
[10236,"'HNRNPR'",1478,1428,1304,1403.33333333333,{"$nulls":4},"GO:0071013///catalytic step 2 spliceosome+++GO:0005737///cytoplasm+++GO:0043679///axon terminus+++GO:0030426///growth cone+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005681///spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0030425///dendrite","GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0061157///mRNA destabilization+++GO:0043086///negative regulation of catalytic activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process+++GO:0061014///positive regulation of mRNA catabolic process","heterogeneous nuclear ribonucleoprotein R","[HNRPR_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein R; Short=hnRNP R;+++[A0A286YEZ8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|Ensembl:ENSP00000493186}; Flags: Fragment;+++[B4DMB1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53358, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59823.1};+++[B4DMD1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53360, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59843.1};+++[B4DT28_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R, isoform CRA_a {ECO:0000313|EMBL:EAW95040.1}; SubName: Full=cDNA FLJ54544, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG61840.1};+++[Q0VGD6_HUMAN|Unreviewed]SubName: Full=HNRPR protein {ECO:0000313|EMBL:AAI10390.1}; Flags: Fragment;+++[Q6MZS5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686A13234 {ECO:0000313|EMBL:CAE45953.1}; Flags: Fragment;"]
[10237,"'SLC35B1'",423,375,423,407,{"$nulls":4},"GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005459///UDP-galactose transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:0008643///carbohydrate transport","solute carrier family 35 member B1","[S35B1_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member B1; AltName: Full=UDP-galactose transporter-related protein 1; Short=UGTrel1; Short=hUGTrel1;+++[D3DTX1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35, member B1, isoform CRA_a {ECO:0000313|EMBL:EAW94669.1};+++[D6R981_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000423323}; Flags: Fragment;+++[D6R9G9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000422104}; Flags: Fragment;+++[D6RB73_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424367}; Flags: Fragment;+++[D6RDY9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000425179};+++[D6RE58_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426961}; Flags: Fragment;+++[D6RF81_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424857}; Flags: Fragment;+++[D6RG34_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426402}; Flags: Fragment;+++[D6RHG0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000427689}; Flags: Fragment;"]
[10238,"'DCAF7'",2099.69,2340.76,2137,2192.48333333333,{"$nulls":4},"GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0043687///post-translational protein modification","DDB1 and CUL4 associated factor 7","[DCAF7_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 7; AltName: Full=WD repeat-containing protein 68; AltName: Full=WD repeat-containing protein An11 homolog;+++[A0A087WWI6_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 7 {ECO:0000313|Ensembl:ENSP00000480250}; Flags: Fragment;"]
[10239,"'AP3S2'",343.8,359.7,262.33,321.943333333333,"04142///Lysosome",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0030123///AP-3 adaptor complex+++GO:1904115///axon cytoplasm+++GO:0030117///membrane coat+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus",null,"GO:0048490///anterograde synaptic vesicle transport+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport","adaptor related protein complex 3 subunit sigma 2","[AP3S2_HUMAN|Reviewed]RecName: Full=AP-3 complex subunit sigma-2; AltName: Full=AP-3 complex subunit sigma-3B; AltName: Full=Adaptor-related protein complex 3 subunit sigma-2; AltName: Full=Sigma-3B-adaptin; Short=Sigma3B-adaptin; AltName: Full=Sigma-adaptin 3b;+++[A0A024RC62_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_a {ECO:0000313|EMBL:EAX02073.1};+++[A0A087WY05_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000481434};+++[H0YKM3_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000452862};+++[H0YLI7_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453223}; SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_d {ECO:0000313|EMBL:EAX02075.1};+++[H0YLX6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453380};+++[H0YN38_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[H0YNI6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000454027};+++[Q6PK37_HUMAN|Unreviewed]SubName: Full=AP3S2 protein {ECO:0000313|EMBL:AAH07773.1}; Flags: Fragment;"]
[1024,"'CDK8'",350,308,300,319.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016592///mediator complex+++GO:0032991///protein-containing complex","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0006468///protein phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016310///phosphorylation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051726///regulation of cell cycle","cyclin dependent kinase 8","[CDK8_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 8; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cell division protein kinase 8; AltName: Full=Mediator complex subunit CDK8; AltName: Full=Mediator of RNA polymerase II transcription subunit CDK8; AltName: Full=Protein kinase K35;+++[A0A0D9SEP3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000485883}; Flags: Fragment;+++[A0A0D9SFZ2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000487013}; Flags: Fragment;+++[F5H6D4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000437696};+++[Q64FY6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:AAU29339.1};+++[U4PPA3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:CDI06887.1}; Flags: Fragment;"]
[10240,"'MRPS31'",135,143,145,141,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05202///Transcriptional misregulation in cancer+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04910///Insulin signaling pathway+++05200///Pathways in cancer+++05215///Prostate cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++04922///Glucagon signaling pathway+++04919///Thyroid hormone signaling pathway+++04068///FoxO signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++05165///Human papillomavirus infection+++04218///Cellular senescence","H00037///Alveolar rhabdomyosarcoma","M00676///PI3K-Akt signaling",null,"GO:0005763///mitochondrial small ribosomal subunit+++GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0005730///nucleolus","GO:0003735///structural constituent of ribosome+++GO:0019904///protein domain specific binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation","mitochondrial ribosomal protein S31","[RT31_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S31, mitochondrial; Short=MRP-S31; Short=S31mt; AltName: Full=Imogen 38; AltName: Full=Mitochondrial small ribosomal subunit protein mS31 {ECO:0000303|PubMed:25838379}; Flags: Precursor;"]
[10241,"'CALCOCO2'",1959,2195,1965,2039.66666666667,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0000421///autophagosome membrane+++GO:0005776///autophagosome+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0016032///viral process+++GO:0034341///response to interferon-gamma+++GO:1901098///positive regulation of autophagosome maturation+++GO:0006914///autophagy+++GO:0098792///xenophagy","calcium binding and coiled-coil domain 2","[CACO2_HUMAN|Reviewed]RecName: Full=Calcium-binding and coiled-coil domain-containing protein 2; AltName: Full=Antigen nuclear dot 52 kDa protein; AltName: Full=Nuclear domain 10 protein NDP52 {ECO:0000305}; Short=Nuclear domain 10 protein 52 {ECO:0000303|PubMed:7540613}; AltName: Full=Nuclear dot protein 52 {ECO:0000303|PubMed:9230084};+++[D6RBF9_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424169}; Flags: Fragment;+++[D6RBI4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422697}; Flags: Fragment;+++[D6REB0_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425090}; Flags: Fragment;+++[D6RF70_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424889}; Flags: Fragment;+++[D6RJE7_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425692}; Flags: Fragment;+++[H0Y9G3_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424083}; Flags: Fragment;+++[H0YBP4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429963}; Flags: Fragment;+++[I3L493_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461083}; Flags: Fragment;+++[I3L4E1_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461184};"]
[10243,"'GPHN'",161,180,130,157,"00790///Folate biosynthesis+++01100///Metabolic pathways+++04727///GABAergic synapse","H00192///Xanthinuria+++H00769///Hyperekplexia",null,"R09735///adenylyl-molybdopterin:molybdate molybdate transferase (AMP-forming)   Adenylated molybdopterin + Molybdate <=> Molybdoenzyme molybdenum cofactor + AMP + H2O+++R09726///ATP:molybdopterin adenylyltransferase   ATP + Molybdopterin <=> Diphosphate + Adenylated molybdopterin","GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0099634///postsynaptic specialization membrane+++GO:0005856///cytoskeleton+++GO:0099572///postsynaptic specialization+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0005829///cytosol","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0061598///molybdopterin adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0008940///nitrate reductase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0061599///molybdopterin molybdotransferase activity+++GO:0043546///molybdopterin cofactor binding","GO:0018315///molybdenum incorporation into molybdenum-molybdopterin complex+++GO:0055114///oxidation-reduction process+++GO:0032324///molybdopterin cofactor biosynthetic process+++GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0007529///establishment of synaptic specificity at neuromuscular junction+++GO:0008152///metabolic process+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0010038///response to metal ion+++GO:0072579///glycine receptor clustering+++GO:0097112///gamma-aminobutyric acid receptor clustering","gephyrin","[GEPH_HUMAN|Reviewed]RecName: Full=Gephyrin {ECO:0000303|PubMed:10839351}; Includes: RecName: Full=Molybdopterin adenylyltransferase; Short=MPT adenylyltransferase; EC=2.7.7.75 {ECO:0000305|PubMed:26613940}; AltName: Full=Domain G; Includes: RecName: Full=Molybdopterin molybdenumtransferase; Short=MPT Mo-transferase; EC=2.10.1.1 {ECO:0000305|PubMed:22040219, ECO:0000305|PubMed:26613940}; AltName: Full=Domain E;+++[F5H039_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000438404};+++[G3V355_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451056};+++[G3V4D2_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451725};+++[G3V4R0_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451935};+++[G3V582_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452220};+++[H0YIY4_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450442}; Flags: Fragment;+++[H0YJ30_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450706}; Flags: Fragment;+++[H0YJR5_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452009}; Flags: Fragment;"]
[10244,"'RABEPK'",215,245,221,227,"04141///Protein processing in endoplasmic reticulum+++03060///Protein export+++04918///Thyroid hormone synthesis+++05020///Prion diseases",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0005737///cytoplasm","GO:0051082///unfolded protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0051787///misfolded protein binding+++GO:0019904///protein domain specific binding+++GO:0043022///ribosome binding+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0016887///ATPase activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051087///chaperone binding","GO:0006904///vesicle docking involved in exocytosis+++GO:0006898///receptor-mediated endocytosis","Rab9 effector protein with kelch motifs","[RABEK_HUMAN|Reviewed]RecName: Full=Rab9 effector protein with kelch motifs; AltName: Full=40 kDa Rab9 effector protein; AltName: Full=p40;+++[A0A024R8A0_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 1 {ECO:0000313|EMBL:ALQ33965.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_c {ECO:0000313|EMBL:EAW87619.1};+++[A0A0S2Z4Z1_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 5 {ECO:0000313|EMBL:ALQ33969.1}; Flags: Fragment;+++[A0A0S2Z4Z5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 4 {ECO:0000313|EMBL:ALQ33968.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_d {ECO:0000313|EMBL:EAW87617.1}; Flags: Fragment;+++[A0A0S2Z506_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 3 {ECO:0000313|EMBL:ALQ33967.1};+++[A0A0S2Z553_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 2 {ECO:0000313|EMBL:ALQ33966.1};+++[Q5T1S4_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000362645};+++[Q5T1S5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000402234}; Flags: Fragment;"]
[10245,"'TIMM17B'",585,561,546,564,{"$nulls":4},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane","GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport","translocase of inner mitochondrial membrane 17B","[TI17B_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B;+++[Q8NCS3_HUMAN|Unreviewed]SubName: Full=TIMM17B protein {ECO:0000313|EMBL:AAH29446.1}; Flags: Fragment;+++[V9GYK7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000476861};+++[V9GYS0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477027};+++[V9GYU0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477085}; Flags: Fragment;"]
[10247,"'RIDA'",83,62,79,74.6666666666667,{"$nulls":3},"R11099///2-iminopropanoate aminohydrolase   2-Iminopropanoate + H2O <=> Pyruvate + Ammonia+++R11098///2-iminobutanoate aminohydrolase   2-Iminobutanoate + H2O <=> 2-Oxobutanoate + Ammonia","GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0042803///protein homodimerization activity+++GO:0036041///long-chain fatty acid binding+++GO:1904013///xenon atom binding+++GO:0016787///hydrolase activity+++GO:0046914///transition metal ion binding+++GO:0003723///RNA binding+++GO:0016892///endoribonuclease activity, producing 3'-phosphomonoesters+++GO:0043167///ion binding+++GO:0019239///deaminase activity+++GO:1904012///platinum binding","GO:1901565///organonitrogen compound catabolic process+++GO:0001822///kidney development+++GO:0019518///L-threonine catabolic process to glycine+++GO:1902074///response to salt+++GO:0070314///G1 to G0 transition+++GO:0017148///negative regulation of translation+++GO:0030324///lung development+++GO:0007420///brain development+++GO:0033993///response to lipid+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","reactive intermediate imine deaminase A homolog","[RIDA_HUMAN|Reviewed]RecName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000305|PubMed:22094463}; EC=3.5.99.10 {ECO:0000269|PubMed:22094463}; AltName: Full=14.5 kDa translational inhibitor protein {ECO:0000303|PubMed:8973653}; Short=hp14.5 {ECO:0000303|PubMed:14997576}; Short=p14.5 {ECO:0000303|PubMed:8973653}; AltName: Full=Heat-responsive protein 12 {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Reactive intermediate imine deaminase A homolog {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Translation inhibitor L-PSP ribonuclease {ECO:0000250|UniProtKB:P52759}; EC=3.1.-.- {ECO:0000250|UniProtKB:P52759}; AltName: Full=UK114 antigen homolog {ECO:0000305|PubMed:20817725};+++[A0A024R9H2_HUMAN|Unreviewed]SubName: Full=Heat-responsive protein 12, isoform CRA_a {ECO:0000313|EMBL:EAW91775.1};+++[E5RIP8_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000429321};+++[H0YB34_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000428596}; Flags: Fragment;+++[H0YBX3_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000430482}; Flags: Fragment;"]
[10248,"'POP7'",396,372,382,383.333333333333,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005634///nucleus+++GO:0000172///ribonuclease MRP complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005654///nucleoplasm","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0001682///tRNA 5'-leader removal+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0008033///tRNA processing","POP7 homolog, ribonuclease P/MRP subunit","[POP7_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p20; Short=RNaseP protein p20; EC=3.1.26.5; AltName: Full=Ribonucleases P/MRP protein subunit POP7 homolog; Short=hPOP7;+++[C9JYM0_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p20 {ECO:0000313|Ensembl:ENSP00000387814}; Flags: Fragment;"]
[1025,"'CDK9'",757,789,730,758.666666666667,"05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005694///chromosome+++GO:0016020///membrane+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0008023///transcription elongation factor complex+++GO:0000790///nuclear chromatin+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0001223///transcription coactivator binding+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0017069///snRNA binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0004672///protein kinase activity+++GO:0030332///cyclin binding+++GO:0097322///7SK snRNA binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0031297///replication fork processing+++GO:0031056///regulation of histone modification+++GO:0006468///protein phosphorylation+++GO:0007346///regulation of mitotic cell cycle+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0071157///negative regulation of cell cycle arrest+++GO:1903839///positive regulation of mRNA 3'-UTR binding+++GO:0016310///phosphorylation+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0006282///regulation of DNA repair+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0042493///response to drug+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0051147///regulation of muscle cell differentiation+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0033129///positive regulation of histone phosphorylation+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0050434///positive regulation of viral transcription","cyclin dependent kinase 9","[CDK9_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 9; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=C-2K; AltName: Full=Cell division cycle 2-like protein kinase 4; AltName: Full=Cell division protein kinase 9; AltName: Full=Serine/threonine-protein kinase PITALRE; AltName: Full=Tat-associated kinase complex catalytic subunit;+++[A0A024R880_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 (CDC2-related kinase), isoform CRA_a {ECO:0000313|EMBL:EAW87697.1};+++[B5BU53_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|EMBL:BAG70103.1};+++[X6RE90_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|Ensembl:ENSP00000395872}; Flags: Fragment;"]
[10250,"'SRRM1'",2456,3021,2664,2713.66666666667,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006405///RNA export from nucleus+++GO:0031124///mRNA 3'-end processing+++GO:0006406///mRNA export from nucleus","serine and arginine repetitive matrix 1","[SRRM1_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 1; AltName: Full=SR-related nuclear matrix protein of 160 kDa; Short=SRm160; AltName: Full=Ser/Arg-related nuclear matrix protein;+++[A0A0S2Z4W1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 1 {ECO:0000313|EMBL:ALQ33970.1}; SubName: Full=Serine/arginine repetitive matrix 1, isoform CRA_a {ECO:0000313|EMBL:EAW95138.1}; Flags: Fragment;+++[A0A0S2Z4Z6_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 2 {ECO:0000313|EMBL:ALQ33971.1}; Flags: Fragment;+++[A9Z1X7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000363510};+++[B7Z7U0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61739, highly similar to Serine/arginine repetitive matrix protein 1 {ECO:0000313|EMBL:BAH13726.1};+++[E9PCT1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000391430};+++[M0QXG5_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000469151}; Flags: Fragment;+++[M0R088_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471084}; Flags: Fragment;+++[M0R1E7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471819};"]
[10251,"'SPRY3'",44,62,61,55.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function","GO:0061564///axon development+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046580///negative regulation of Ras protein signal transduction","sprouty RTK signaling antagonist 3","[SPY3_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 3; Short=Spry-3;+++[Q6ZUP3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43494 fis, clone PEBLM2000170, moderately similar to Sprouty homolog 3 {ECO:0000313|EMBL:BAC86177.1};"]
[10252,"'SPRY1'",44,74,81,66.3333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0009966///regulation of signal transduction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0001656///metanephros development+++GO:0007275///multicellular organism development+++GO:0001759///organ induction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0001657///ureteric bud development+++GO:0008285///negative regulation of cell proliferation+++GO:0060940///epithelial to mesenchymal transition involved in cardiac fibroblast development+++GO:0060449///bud elongation involved in lung branching","sprouty RTK signaling antagonist 1","[SPY1_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 1; Short=Spry-1;+++[D6REX7_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421622}; Flags: Fragment;+++[D6RHD2_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421036}; Flags: Fragment;+++[D6RIE6_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000425946}; Flags: Fragment;+++[L8E896_HUMAN|Unreviewed]SubName: Full=Alternative protein SPRY1 {ECO:0000313|EMBL:CCQ43339.1};"]
[10253,"'SPRY2'",782,657,817,752,"04013///MAPK signaling pathway - fly+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015630///microtubule cytoskeleton+++GO:0042995///cell projection+++GO:0032587///ruffle membrane+++GO:0005634///nucleus","GO:0043539///protein serine/threonine kinase activator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity","GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0034260///negative regulation of GTPase activity+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0060541///respiratory system development+++GO:0030324///lung development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0016525///negative regulation of angiogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0031345///negative regulation of cell projection organization+++GO:0030335///positive regulation of cell migration+++GO:0060437///lung growth+++GO:0043407///negative regulation of MAP kinase activity+++GO:0007275///multicellular organism development+++GO:0045595///regulation of cell differentiation+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0060425///lung morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0045165///cell fate commitment+++GO:0060449///bud elongation involved in lung branching+++GO:0010628///positive regulation of gene expression+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0042127///regulation of cell proliferation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway","sprouty RTK signaling antagonist 2","[SPY2_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 2; Short=Spry-2;"]
[10254,"'STAM2'",346,337,363,348.666666666667,"04630///Jak-STAT signaling pathway+++04144///Endocytosis",null,"M00408///ESCRT-0 complex",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0033565///ESCRT-0 complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome","GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0036258///multivesicular body assembly+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0061024///membrane organization+++GO:0016236///macroautophagy+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport","signal transducing adaptor molecule 2","[STAM2_HUMAN|Reviewed]RecName: Full=Signal transducing adapter molecule 2; Short=STAM-2; AltName: Full=Hrs-binding protein;"]
[10256,"'CNKSR1'",24,54,32,36.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0007266///Rho protein signal transduction","connector enhancer of kinase suppressor of Ras 1","[CNKR1_HUMAN|Reviewed]RecName: Full=Connector enhancer of kinase suppressor of ras 1; Short=Connector enhancer of KSR 1; AltName: Full=CNK homolog protein 1; Short=CNK1; Short=hCNK1; AltName: Full=Connector enhancer of KSR-like;+++[B4DL25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60656, highly similar to Connector enhancer of kinase suppressor ofras 1 {ECO:0000313|EMBL:BAG59387.1};+++[B4DXN4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59272, highly similar to Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|EMBL:BAG63446.1};+++[E9PIE0_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000432057};+++[E9PS82_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000435880};+++[G3V160_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_a {ECO:0000313|EMBL:EAX07840.1}; SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000431817};+++[H0YDP5_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000434047}; Flags: Fragment;+++[Q53GM7_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1 variant {ECO:0000313|EMBL:BAD96624.1}; SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_b {ECO:0000313|EMBL:EAX07841.1}; Flags: Fragment;"]
[10257,"'ABCC4'",167,123,162,150.666666666667,"02010///ABC transporters+++04976///Bile secretion+++04024///cAMP signaling pathway+++01523///Antifolate resistance",{"$nulls":3},"GO:0031088///platelet dense granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0016404///15-hydroxyprostaglandin dehydrogenase (NAD+) activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances","GO:0055085///transmembrane transport+++GO:0010243///response to organonitrogen compound+++GO:0060271///cilium assembly+++GO:0008150///biological_process+++GO:0002576///platelet degranulation+++GO:0010033///response to organic substance+++GO:0099131///ATP hydrolysis coupled ion transmembrane transport+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0042493///response to drug+++GO:0014070///response to organic cyclic compound+++GO:0032310///prostaglandin secretion+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0055114///oxidation-reduction process","ATP binding cassette subfamily C member 4","[MRP4_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 4; AltName: Full=ATP-binding cassette sub-family C member 4; AltName: Full=MRP/cMOAT-related ABC transporter; AltName: Full=Multi-specific organic anion transporter B; Short=MOAT-B;+++[A0A2R8Y5Z3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494938}; Flags: Fragment;+++[A0A2R8Y6V8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000495513};+++[A0A2R8YDC1_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494431}; Flags: Fragment;+++[A0A2R8YDG7_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493766};+++[A8K2Q2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77042, highly similar to Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4, mRNA {ECO:0000313|EMBL:BAF83006.1};+++[O75555_HUMAN|Unreviewed]SubName: Full=ABC transporter MOAT-B isoform {ECO:0000313|EMBL:AAC27077.1}; Flags: Fragment;+++[Q8IUA3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 1 {ECO:0000313|EMBL:AAN08629.1}; SubName: Full=ATP-binding cassette subfamily C member 4 variant 3 {ECO:0000313|EMBL:AAN08630.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_a {ECO:0000313|EMBL:EAX08949.1};+++[Q8IWU1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 2 {ECO:0000313|EMBL:AAN08628.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_d {ECO:0000313|EMBL:EAX08952.1}; SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493861};"]
[1026,"'CDKN1A'",5227,3646,4167,4346.66666666667,"04928///Parathyroid hormone synthesis, secretion and action+++01522///Endocrine resistance+++05219///Bladder cancer+++04921///Oxytocin signaling pathway+++05203///Viral carcinogenesis+++05226///Gastric cancer+++05165///Human papillomavirus infection+++04066///HIF-1 signaling pathway+++05217///Basal cell carcinoma+++04068///FoxO signaling pathway+++04012///ErbB signaling pathway+++05215///Prostate cancer+++05225///Hepatocellular carcinoma+++04934///Cushing's syndrome+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++01524///Platinum drug resistance+++05218///Melanoma+++05166///HTLV-I infection+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++05160///Hepatitis C+++04115///p53 signaling pathway+++05220///Chronic myeloid leukemia+++04110///Cell cycle+++05212///Pancreatic cancer+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05161///Hepatitis B+++05223///Non-small cell lung cancer+++05214///Glioma+++04630///Jak-STAT signaling pathway+++05222///Small cell lung cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05211///Renal cell carcinoma+++04218///Cellular senescence+++05224///Breast cancer+++05163///Human cytomegalovirus infection+++05213///Endometrial cancer+++05216///Thyroid cancer","H00030///Cervical cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0070557///PCNA-p21 complex+++GO:0032991///protein-containing complex+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex","GO:0044877///protein-containing complex binding+++GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019912///cyclin-dependent protein kinase activating kinase activity+++GO:0016301///kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0030332///cyclin binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:0009636///response to toxic substance+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:0090398///cellular senescence+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010243///response to organonitrogen compound+++GO:0072331///signal transduction by p53 class mediator+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0071850///mitotic cell cycle arrest+++GO:0006974///cellular response to DNA damage stimulus+++GO:0055093///response to hyperoxia+++GO:0034198///cellular response to amino acid starvation+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0042326///negative regulation of phosphorylation+++GO:0010165///response to X-ray+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0051412///response to corticosterone+++GO:0014070///response to organic cyclic compound+++GO:0010033///response to organic substance+++GO:0043066///negative regulation of apoptotic process+++GO:0042493///response to drug+++GO:0046685///response to arsenic-containing substance+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0090399///replicative senescence+++GO:0007265///Ras protein signal transduction+++GO:0090400///stress-induced premature senescence+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034605///cellular response to heat+++GO:0045860///positive regulation of protein kinase activity+++GO:0071493///cellular response to UV-B+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0060574///intestinal epithelial cell maturation+++GO:0007050///cell cycle arrest+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0031668///cellular response to extracellular stimulus+++GO:0007346///regulation of mitotic cell cycle+++GO:0051384///response to glucocorticoid+++GO:0031100///animal organ regeneration+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050821///protein stabilization+++GO:0007507///heart development+++GO:0030308///negative regulation of cell growth+++GO:0071479///cellular response to ionizing radiation+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle","cyclin dependent kinase inhibitor 1A","[CDN1A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1; AltName: Full=CDK-interacting protein 1; AltName: Full=Melanoma differentiation-associated protein 6; Short=MDA-6; AltName: Full=p21;+++[A0A024RCX5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_a {ECO:0000313|EMBL:EAX03907.1};"]
[10260,"'DENND4A'",474,484,394,450.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0006355///regulation of transcription, DNA-templated","DENN domain containing 4A","[MYCPP_HUMAN|Reviewed]RecName: Full=C-myc promoter-binding protein; AltName: Full=DENN domain-containing protein 4A;+++[A0A0U1RR27_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000489304};+++[H3BSA0_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000456605}; Flags: Fragment;+++[H3BTW5_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000457358}; Flags: Fragment;+++[Q05C90_HUMAN|Unreviewed]SubName: Full=DENND4A protein {ECO:0000313|EMBL:AAH28057.1}; Flags: Fragment;"]
[10262,"'SF3B4'",1600,1502,1549,1550.33333333333,"03040///Spliceosome","H01376///Acrofacial dysostosis","M00352///Spliceosome, U2-snRNP",null,"GO:0005912///adherens junction+++GO:0005913///cell-cell adherens junction+++GO:0045177///apical part of cell+++GO:0016607///nuclear speck+++GO:0005730///nucleolus+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0070160///tight junction+++GO:0030054///cell junction+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0051015///actin filament binding+++GO:0050839///cell adhesion molecule binding+++GO:0003676///nucleic acid binding+++GO:0045296///cadherin binding+++GO:0017016///Ras GTPase binding+++GO:0003723///RNA binding","GO:0061951///establishment of protein localization to plasma membrane+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0034332///adherens junction organization+++GO:0060019///radial glial cell differentiation+++GO:0007267///cell-cell signaling+++GO:0060563///neuroepithelial cell differentiation+++GO:0043547///positive regulation of GTPase activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0007165///signal transduction+++GO:0007155///cell adhesion+++GO:0048872///homeostasis of number of cells+++GO:0034334///adherens junction maintenance+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0032880///regulation of protein localization+++GO:0030336///negative regulation of cell migration+++GO:0048854///brain morphogenesis+++GO:0021987///cerebral cortex development+++GO:1902414///protein localization to cell junction+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0008380///RNA splicing+++GO:0070830///bicellular tight junction assembly+++GO:0021537///telencephalon development","splicing factor 3b subunit 4","[SF3B4_HUMAN|Reviewed]RecName: Full=Splicing factor 3B subunit 4; AltName: Full=Pre-mRNA-splicing factor SF3b 49 kDa subunit; AltName: Full=Spliceosome-associated protein 49; Short=SAP 49;+++[B3KUJ0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39996 fis, clone STOMA2002166, highly similar to Splicing factor 3B subunit 4 {ECO:0000313|EMBL:BAG53452.1};+++[Q5SZ64_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 4 {ECO:0000313|Ensembl:ENSP00000391114}; SubName: Full=Splicing factor 3b, subunit 4, 49kDa {ECO:0000313|EMBL:CAI12647.1}; Flags: Fragment;"]
[10263,"'CDK2AP2'",1071,1121,1063,1085,{"$nulls":4},"GO:0005874///microtubule+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:2000035///regulation of stem cell division","cyclin dependent kinase 2 associated protein 2","[CDKA2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein 2; Short=CDK2-associated protein 2; AltName: Full=DOC-1-related protein; Short=DOC-1R;+++[E9PKR4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000431503};+++[E9PQJ3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000436213};+++[Q6IAV4_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein {ECO:0000256|PIRNR:PIRNR037709};"]
[10265,"'IRX5'",1,1,1,1,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005499///vitamin D binding+++GO:0003677///DNA binding","GO:0048468///cell development+++GO:0060040///retinal bipolar neuron differentiation+++GO:0010468///regulation of gene expression+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0042551///neuron maturation+++GO:0050896///response to stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007601///visual perception+++GO:0008406///gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0002027///regulation of heart rate","iroquois homeobox 5","[IRX5_HUMAN|Reviewed]RecName: Full=Iroquois-class homeodomain protein IRX-5; AltName: Full=Homeodomain protein IRX-2A; AltName: Full=Homeodomain protein IRXB2; AltName: Full=Iroquois homeobox protein 5;+++[A2RRB5_HUMAN|Unreviewed]SubName: Full=IRX5 protein {ECO:0000313|EMBL:AAI31511.1}; SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000483446};+++[H0YML8_HUMAN|Unreviewed]SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000453660};"]
[10266,"'RAMP2'",11,9,9,9.66666666666667,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0150057///amylin receptor complex 2+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005887///integral component of plasma membrane+++GO:0005623///cell+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:1903143///adrenomedullin receptor complex+++GO:0043235///receptor complex","GO:0005515///protein binding+++GO:0001605///adrenomedullin receptor activity+++GO:0008565///protein transporter activity+++GO:0097643///amylin receptor activity+++GO:0015026///coreceptor activity+++GO:1990409///adrenomedullin binding","GO:0043116///negative regulation of vascular permeability+++GO:2001214///positive regulation of vasculogenesis+++GO:0002040///sprouting angiogenesis+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032570///response to progesterone+++GO:0031623///receptor internalization+++GO:0001666///response to hypoxia+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0001570///vasculogenesis+++GO:0006816///calcium ion transport+++GO:0070830///bicellular tight junction assembly+++GO:0008217///regulation of blood pressure+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006886///intracellular protein transport+++GO:0032355///response to estradiol+++GO:0015031///protein transport+++GO:0097084///vascular smooth muscle cell development+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0070831///basement membrane assembly+++GO:0097647///amylin receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0001525///angiogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0034333///adherens junction assembly+++GO:0045766///positive regulation of angiogenesis+++GO:0007565///female pregnancy+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010628///positive regulation of gene expression","receptor activity modifying protein 2","[RAMP2_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 2; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 2; Short=CRLR activity-modifying protein 2; Flags: Precursor;+++[A0A024R1Z2_HUMAN|Unreviewed]SubName: Full=Receptor (Calcitonin) activity modifying protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW60878.1};+++[K7EKQ3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000465725};+++[K7ENJ8_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000466980}; Flags: Fragment;+++[K7EPN3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000467463};"]
[10267,"'RAMP1'",187,156,203,182,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:1990406///CGRP receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0150056///amylin receptor complex 1+++GO:0009986///cell surface+++GO:0005623///cell+++GO:0043235///receptor complex+++GO:0005886///plasma membrane","GO:0097643///amylin receptor activity+++GO:1990407///calcitonin gene-related peptide binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0008565///protein transporter activity+++GO:0015026///coreceptor activity+++GO:0005515///protein binding","GO:0060050///positive regulation of protein glycosylation+++GO:0006886///intracellular protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0001525///angiogenesis+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0015031///protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0097647///amylin receptor signaling pathway+++GO:0031623///receptor internalization+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0006816///calcium ion transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway","receptor activity modifying protein 1","[RAMP1_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 1; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 1; Short=CRLR activity-modifying protein 1; Flags: Precursor;+++[E9PC20_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 1 {ECO:0000313|Ensembl:ENSP00000386720};+++[Q53SN3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY24219.1}; Flags: Fragment;+++[Q53T50_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY14674.1}; Flags: Fragment;"]
[10268,"'RAMP3'",1,1,1,1,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005623///cell+++GO:0005764///lysosome+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0016021///integral component of membrane+++GO:1903143///adrenomedullin receptor complex+++GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0150058///amylin receptor complex 3","GO:0008565///protein transporter activity+++GO:0001605///adrenomedullin receptor activity+++GO:0001540///amyloid-beta binding+++GO:0015026///coreceptor activity+++GO:0097643///amylin receptor activity+++GO:0005515///protein binding","GO:0001921///positive regulation of receptor recycling+++GO:0006886///intracellular protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:0086103///G protein-coupled receptor signaling pathway involved in heart process+++GO:0010739///positive regulation of protein kinase A signaling+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0006816///calcium ion transport+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0031623///receptor internalization+++GO:0038041///cross-receptor inhibition within G protein-coupled receptor heterodimer+++GO:0010628///positive regulation of gene expression+++GO:0001525///angiogenesis+++GO:0097647///amylin receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1904645///response to amyloid-beta+++GO:0072659///protein localization to plasma membrane+++GO:0010942///positive regulation of cell death+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:0015031///protein transport","receptor activity modifying protein 3","[RAMP3_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 3; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 3; Short=CRLR activity-modifying protein 3; Flags: Precursor;+++[A4D2L1_HUMAN|Unreviewed]SubName: Full=Receptor (Calcitonin) activity modifying protein 3 {ECO:0000313|EMBL:EAL23743.1}; SubName: Full=Receptor (Calcitonin) activity modifying protein 3, isoform CRA_a {ECO:0000313|EMBL:EAW61048.1}; SubName: Full=cDNA, FLJ92137, Homo sapiens receptor (calcitonin) activity modifying protein 3(RAMP3), mRNA {ECO:0000313|EMBL:BAG34812.1};+++[J3KR56_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 3 {ECO:0000313|Ensembl:ENSP00000418460};+++[L8E7U1_HUMAN|Unreviewed]SubName: Full=Alternative protein RAMP3 {ECO:0000313|EMBL:CCQ43340.1};+++[M5AMS3_HUMAN|Unreviewed]SubName: Full=Receptor (G protein-coupled) activity modifying protein 3 {ECO:0000313|EMBL:BAN10198.1}; Flags: Fragment;+++[M5AP16_HUMAN|Unreviewed]SubName: Full=Receptor (G protein-coupled) activity modifying protein 3 {ECO:0000313|EMBL:BAN10197.1}; Flags: Fragment;"]
[10269,"'ZMPSTE24'",746,594,554,631.333333333333,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis","H00665///Mandibuloacral dysplasia+++H00663///Restrictive dermopathy",null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005635///nuclear envelope+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0004175///endopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0008235///metalloexopeptidase activity+++GO:0016787///hydrolase activity+++GO:0003690///double-stranded DNA binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0046872///metal ion binding","GO:0061337///cardiac conduction+++GO:0051276///chromosome organization+++GO:0060993///kidney morphogenesis+++GO:0003231///cardiac ventricle development+++GO:0003007///heart morphogenesis+++GO:0032006///regulation of TOR signaling+++GO:0032350///regulation of hormone metabolic process+++GO:0006998///nuclear envelope organization+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0040014///regulation of multicellular organism growth+++GO:0003417///growth plate cartilage development+++GO:0010629///negative regulation of gene expression+++GO:1990164///histone H2A phosphorylation+++GO:0090239///regulation of histone H4 acetylation+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:1903522///regulation of blood circulation+++GO:0007628///adult walking behavior+++GO:1903463///regulation of mitotic cell cycle DNA replication+++GO:0050905///neuromuscular process+++GO:0008016///regulation of heart contraction+++GO:0044030///regulation of DNA methylation+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:0006508///proteolysis+++GO:0070302///regulation of stress-activated protein kinase signaling cascade+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0030327///prenylated protein catabolic process+++GO:0071586///CAAX-box protein processing+++GO:0010506///regulation of autophagy+++GO:0001889///liver development+++GO:0010628///positive regulation of gene expression+++GO:0072423///response to DNA damage checkpoint signaling+++GO:0030500///regulation of bone mineralization+++GO:0044029///hypomethylation of CpG island+++GO:0048538///thymus development+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0043969///histone H2B acetylation+++GO:0035264///multicellular organism growth+++GO:0006281///DNA repair+++GO:0048145///regulation of fibroblast proliferation+++GO:0019216///regulation of lipid metabolic process+++GO:0006997///nucleus organization+++GO:0006325///chromatin organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0050688///regulation of defense response to virus+++GO:0008544///epidermis development+++GO:0030282///bone mineralization+++GO:0043007///maintenance of rDNA+++GO:1990036///calcium ion import into sarcoplasmic reticulum+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001942///hair follicle development+++GO:0006925///inflammatory cell apoptotic process+++GO:0008340///determination of adult lifespan+++GO:0016485///protein processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0010906///regulation of glucose metabolic process+++GO:0048739///cardiac muscle fiber development+++GO:2000772///regulation of cellular senescence+++GO:0044255///cellular lipid metabolic process+++GO:0008360///regulation of cell shape+++GO:2000618///regulation of histone H4-K16 acetylation+++GO:0071480///cellular response to gamma radiation+++GO:0043979///histone H2B-K5 acetylation+++GO:2000730///regulation of termination of RNA polymerase I transcription","zinc metallopeptidase STE24","[FACE1_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 1 homolog; EC=3.4.24.84; AltName: Full=Farnesylated proteins-converting enzyme 1; Short=FACE-1; AltName: Full=Prenyl protein-specific endoprotease 1; AltName: Full=Zinc metalloproteinase Ste24 homolog;"]
[1027,"'CDKN1B'",578,692,613,627.666666666667,"05226///Gastric cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing's syndrome+++05206///MicroRNAs in cancer+++04066///HIF-1 signaling pathway+++05222///Small cell lung cancer+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++04012///ErbB signaling pathway+++05220///Chronic myeloid leukemia+++05169///Epstein-Barr virus infection+++05215///Prostate cancer+++05161///Hepatitis B+++04110///Cell cycle+++05162///Measles+++05203///Viral carcinogenesis","H00024///Prostate cancer+++H00018///Gastric cancer+++H01431///Cushing's syndrome+++H01102///Pituitary adenomas+++H00247///Multiple endocrine neoplasia syndrome (MEN)",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032991///protein-containing complex+++GO:0005768///endosome","GO:0051087///chaperone binding+++GO:0019903///protein phosphatase binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005072///transforming growth factor beta receptor, cytoplasmic mediator activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0044877///protein-containing complex binding","GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0051271///negative regulation of cellular component movement+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0043434///response to peptide hormone+++GO:0046686///response to cadmium ion+++GO:0009749///response to glucose+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0048839///inner ear development+++GO:0033673///negative regulation of kinase activity+++GO:0071285///cellular response to lithium ion+++GO:0045930///negative regulation of mitotic cell cycle+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042326///negative regulation of phosphorylation+++GO:0071236///cellular response to antibiotic+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007049///cell cycle+++GO:0014070///response to organic cyclic compound+++GO:0008219///cell death+++GO:0010942///positive regulation of cell death+++GO:0001666///response to hypoxia+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0008284///positive regulation of cell proliferation+++GO:0001890///placenta development+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0006813///potassium ion transport+++GO:0042493///response to drug+++GO:0045786///negative regulation of cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0031116///positive regulation of microtubule polymerization+++GO:0043200///response to amino acid+++GO:0071407///cellular response to organic cyclic compound+++GO:0007096///regulation of exit from mitosis+++GO:0042127///regulation of cell proliferation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest+++GO:0007507///heart development+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0007219///Notch signaling pathway+++GO:0007605///sensory perception of sound+++GO:0071850///mitotic cell cycle arrest+++GO:0045732///positive regulation of protein catabolic process+++GO:0032355///response to estradiol","cyclin dependent kinase inhibitor 1B","[CDN1B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1B; AltName: Full=Cyclin-dependent kinase inhibitor p27 {ECO:0000303|PubMed:28666995}; AltName: Full=p27Kip1 {ECO:0000303|PubMed:8033212};+++[A7KMP4_HUMAN|Unreviewed]SubName: Full=Truncated cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:ABS17636.1};+++[E7ES52_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000379629};+++[H7C2T1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000407597}; Flags: Fragment;+++[Q6I9V6_HUMAN|Unreviewed]SubName: Full=CDKN1B protein {ECO:0000313|EMBL:CAG33680.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:BAG70105.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B (P27, Kip1), isoform CRA_a {ECO:0000313|EMBL:EAW96275.1}; SubName: Full=cDNA, FLJ92816, Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1)(CDKN1B), mRNA {ECO:0000313|EMBL:BAG35368.1};+++[Q708J1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:CAE82383.1}; Flags: Fragment;"]
[10270,"'AKAP8'",419,505,418,447.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001939///female pronucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000793///condensed chromosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0046872///metal ion binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051059///NF-kappaB binding+++GO:0003723///RNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0042826///histone deacetylase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0002376///immune system process+++GO:0000278///mitotic cell cycle+++GO:0031065///positive regulation of histone deacetylation+++GO:0044839///cell cycle G2/M phase transition+++GO:0033127///regulation of histone phosphorylation+++GO:0007165///signal transduction+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0007076///mitotic chromosome condensation+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0015031///protein transport+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response","A-kinase anchoring protein 8","[AKAP8_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 8; Short=AKAP-8; AltName: Full=A-kinase anchor protein 95 kDa; Short=AKAP 95;+++[M0QX51_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000468902};+++[M0QYL4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000469908}; Flags: Fragment;+++[Q8NE02_HUMAN|Unreviewed]SubName: Full=AKAP8 protein {ECO:0000313|EMBL:AAH37270.1};"]
[10272,"'FSTL3'",14853,11326,10991,12390,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0030141///secretory granule+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0044306///neuron projection terminus+++GO:0005576///extracellular region","GO:0001968///fibronectin binding+++GO:0048185///activin binding+++GO:0005515///protein binding","GO:0030325///adrenal gland development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0044267///cellular protein metabolic process+++GO:0030324///lung development+++GO:0007283///spermatogenesis+++GO:0001822///kidney development+++GO:0043687///post-translational protein modification+++GO:0001503///ossification+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0008584///male gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0071248///cellular response to metal ion+++GO:0090101///negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045671///negative regulation of osteoclast differentiation","follistatin like 3","[FSTL3_HUMAN|Reviewed]RecName: Full=Follistatin-related protein 3; AltName: Full=Follistatin-like protein 3; AltName: Full=Follistatin-related gene protein; Flags: Precursor;+++[A0A024R1Y8_HUMAN|Unreviewed]SubName: Full=Follistatin-like 3 (Secreted glycoprotein), isoform CRA_a {ECO:0000313|EMBL:EAW61166.1};+++[A0A087WTD3_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000477770}; Flags: Fragment;+++[A0A087X1Q2_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000484376}; Flags: Fragment;+++[K7EM71_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000466383};"]
[102723360,"'LOC102723360'",1.24,41.41,39.7,27.45,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding","GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression","uncharacterized LOC102723360","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102723475,"'KCNE1B'",16.18,5.44,5.22,8.94666666666667,{"$nulls":4},"GO:0008076///voltage-gated potassium channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005251///delayed rectifier potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding","GO:0006811///ion transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0097623///potassium ion export across plasma membrane+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086011///membrane repolarization during action potential+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport","potassium voltage-gated channel subfamily E regulatory subunit 1B","[KCE1B_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000305};+++[A0A087WU88_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000478461};+++[A0A087WWU3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000480511}; Flags: Fragment;"]
[102723502,"'LOC102723502'",0,1,0,0.333333333333333,{"$nulls":7},"POTE ankyrin domain family member B-like","[A0A0G2JMU2_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000479963};+++[A0A0G2JQB7_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000485729};"]
[102723534,"'LOC102723534'",10,20.82,7.96,12.9266666666667,"04120///Ubiquitin mediated proteolysis","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0032183///SUMO binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0007283///spermatogenesis+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006886///intracellular protein transport","E3 ubiquitin-protein ligase HERC2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[102723553,"'SMIM11B'",194.45,235.76,186.71,205.64,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"small integral membrane protein 11B","[SI11A_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11A {ECO:0000312|HGNC:HGNC:1293};+++[SI11B_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11B {ECO:0000312|HGNC:HGNC:51846};"]
[102723555,"'SPDYE16'",1,1.38,4.48,2.28666666666667,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E16","[SPD16_HUMAN|Reviewed]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[A0A0J9YVZ0_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487736};+++[A0A0J9YW45_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487806};+++[A0A0J9YWM7_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488034};+++[A0A0J9YYB4_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488772};+++[A0A0J9YYF2_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488825};"]
[102723623,"'LOC102723623'",1,0,0,0.333333333333333,{"$nulls":7},"golgin subfamily A member 6-like protein 6","[GG6L1_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 1;+++[GG6L2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 2;+++[GG6L6_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 6;+++[GG6L7_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 7 {ECO:0000305};+++[GG6LV_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};"]
[102723722,"'LOC102723722'",0,7.39,2.6,3.33,"01522///Endocrine resistance+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse","H01171///Poor drug metabolism (PM)",null,"R09421///4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP++++R08343///Citalopram <=> Demethylcitalopram+++R08345///Demethylcitalopram <=> Didemethylcitalopram+++R08344///Citalopram <=> Citalopram N-oxide+++R03697///Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen+++R08270///N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O+++R08267///Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O","GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005783///endoplasmic reticulum","GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0005506///iron ion binding+++GO:0004497///monooxygenase activity+++GO:0046872///metal ion binding+++GO:0008144///drug binding+++GO:0043023///ribosomal large subunit binding+++GO:0016491///oxidoreductase activity+++GO:0016887///ATPase activity+++GO:0008395///steroid hydroxylase activity+++GO:0005524///ATP binding+++GO:0043022///ribosome binding+++GO:0070330///aromatase activity+++GO:0005525///GTP binding+++GO:0020037///heme binding","GO:0090350///negative regulation of cellular organofluorine metabolic process+++GO:0017144///drug metabolic process+++GO:0016098///monoterpenoid metabolic process+++GO:0042737///drug catabolic process+++GO:0046034///ATP metabolic process+++GO:0051100///negative regulation of binding+++GO:0009820///alkaloid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0009804///coumarin metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0046483///heterocycle metabolic process+++GO:0033076///isoquinoline alkaloid metabolic process+++GO:0070989///oxidative demethylation+++GO:0009822///alkaloid catabolic process+++GO:0008202///steroid metabolic process+++GO:0042759///long-chain fatty acid biosynthetic process","uncharacterized LOC102723722","[CP2D6_HUMAN|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000269|PubMed:21576599}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000305|PubMed:21576599}; AltName: Full=Cytochrome P450-DB1; AltName: Full=Debrisoquine 4-hydroxylase;+++[CP2D6_PANPA|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D6_PANTR|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D7_HUMAN|diamond]RecName: Full=Putative cytochrome P450 2D7 {ECO:0000305}; EC=1.14.14.1 {ECO:0000269|PubMed:15051713};+++[CP2DH_MACFA|diamond]RecName: Full=Cytochrome P450 2D17; EC=1.14.14.1; AltName: Full=CYPIID17;+++[OLA1_BOVIN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_HUMAN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=DNA damage-regulated overexpressed in cancer 45; Short=DOC45; AltName: Full=GTP-binding protein 9;+++[OLA1_MOUSE|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=GTP-binding protein 9;+++[OLA1_PONAB|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_RAT|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};"]
[102723728,"'LOC102723728'",1494.03,1121.05,1286.03,1300.37,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding",null,"nodal modulator 3-like","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;"]
[102723750,"'LOC102723750'",10,8,3,7,{"$nulls":7},"uncharacterized LOC102723750","[K7DZX1_MONDO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000039072};+++[K7FQE9_PELSI|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000010259};"]
[102723849,"'SPDYE17'",0,1,0,0.333333333333333,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E17","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE2_HUMAN|diamond]RecName: Full=Speedy protein E2;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPE2B_HUMAN|diamond]RecName: Full=Speedy protein E2B;"]
[102723859,"'TBC1D3E'",105.34,113.24,103.32,107.3,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3E","[TBC3E_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3E {ECO:0000312|HGNC:HGNC:27071};"]
[102723996,"'LOC102723996'",92.83,76.29,40.28,69.8,"04672///Intestinal immune network for IgA production+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0009986///cell surface+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding+++GO:0005102///signaling receptor binding","GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0042102///positive regulation of T cell proliferation+++GO:0031295///T cell costimulation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0042130///negative regulation of T cell proliferation+++GO:0006955///immune response","ICOS ligand","[ICOSL_HUMAN|Reviewed]RecName: Full=ICOS ligand; AltName: Full=B7 homolog 2; Short=B7-H2; AltName: Full=B7-like protein Gl50; AltName: Full=B7-related protein 1; Short=B7RP-1; AltName: CD_antigen=CD275; Flags: Precursor;+++[A0A087X1L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000484302};+++[A0A096LPE5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485557};+++[A0N0L8_HUMAN|Unreviewed]SubName: Full=Inducible T-cell co-stimulator ligand {ECO:0000313|EMBL:ABK41909.1}; SubName: Full=Inducible T-cell co-stimulator ligand, isoform CRA_c {ECO:0000313|EMBL:EAX09448.1}; SubName: Full=cDNA FLJ77643, highly similar to Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAF82881.1}; SubName: Full=cDNA, FLJ95137, Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAG36999.1};"]
[102724023,"'GATD3B'",258.63,212.63,193.58,221.613333333333,{"$nulls":4},"GO:0005739///mitochondrion",null,null,"glutamine amidotransferase like class 1 domain containing 3B","[GAL3B_HUMAN|Reviewed]RecName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial; AltName: Full=Keio novel protein-I {ECO:0000303|PubMed:8753807}; Short=KNP-I {ECO:0000303|PubMed:8753807}; AltName: Full=Protein GT335 {ECO:0000303|PubMed:8975701}; AltName: Full=Protein HES1 {ECO:0000303|PubMed:9150728}; Flags: Precursor;+++[A0A096LNH5_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000483086};+++[A0A096LNJ1_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485058}; Flags: Fragment;+++[A0A096LP12_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000374340}; SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485335}; Flags: Fragment;+++[A0A096LP57_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485404};+++[A0A096LP73_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485439}; Flags: Fragment;+++[A0A0B4J2H4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485300};"]
[102724135,"'LOC102724135'",20.29,24.44,15.33,20.02,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0004691///cAMP-dependent protein kinase activity","GO:0035023///regulation of Rho protein signal transduction","uncharacterized LOC102724135","[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOG8S_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8S {ECO:0000305};"]
[102724151,"'LOC102724151'",0,3,0,1,{"$nulls":7},"putative POM121-like protein 1","[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[102724159,"'LOC102724159'",182.34,155.08,161.32,166.246666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0032040///small-subunit processome","GO:0030515///snoRNA binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","periodic tryptophan protein 2 homolog","[PWP2_HUMAN|Reviewed]RecName: Full=Periodic tryptophan protein 2 homolog;+++[A0A0B4J2E5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000482107};+++[A0A0J9YX21_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000488213}; Flags: Fragment;"]
[102724197,"'LOC102724197'",7.58,2.02,2.04,3.88,"01100///Metabolic pathways+++00460///Cyanoamino acid metabolism+++00430///Taurine and hypotaurine metabolism+++00590///Arachidonic acid metabolism+++00480///Glutathione metabolism",null,null,"R09875///leukotriene-C4 hydrolase Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate+++R01687///(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase (5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine+++R00494///glutathione gamma-glutamylaminopeptidase Glutathione + H2O <=> Cys-Gly + L-Glutamate+++R03970///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase 3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O+++R03971///gamma-glutamyl-beta-aminopropiononitrile amidohydrolase 3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O+++R01262///glutathione:L-amino-acid 5-glutamyltransferase Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid+++R03916///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate","GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0036374///glutathione hydrolase activity+++GO:0000048///peptidyltransferase activity","GO:0006749///glutathione metabolic process+++GO:0019344///cysteine biosynthetic process+++GO:0031638///zymogen activation+++GO:0006751///glutathione catabolic process+++GO:0002682///regulation of immune system process+++GO:0006520///cellular amino acid metabolic process+++GO:0006412///translation+++GO:0031179///peptide modification+++GO:1901750///leukotriene D4 biosynthetic process+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0050727///regulation of inflammatory response+++GO:0032355///response to estradiol+++GO:0034612///response to tumor necrosis factor+++GO:0032496///response to lipopolysaccharide+++GO:0006536///glutamate metabolic process","inactive glutathione hydrolase 2","[GGT2_HUMAN|Reviewed]RecName: Full=Inactive glutathione hydrolase 2; AltName: Full=Gamma-glutamyltransferase 2; AltName: Full=Inactive gamma-glutamyltranspeptidase 2; Short=GGT 2; Flags: Precursor;+++[B5MCK8_HUMAN|Unreviewed]SubName: Full=Inactive glutathione hydrolase 2 {ECO:0000313|Ensembl:ENSP00000385601};"]
[102724200,"'LOC102724200'",12.36,0,9.1,7.15333333333333,{"$nulls":4},"GO:1990071///TRAPPII protein complex+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0034498///early endosome to Golgi transport","trafficking protein particle complex subunit 10-like","[A0A096LPH7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485615}; Flags: Fragment;"]
[102724219,"'LOC102724219'",99.31,100.26,137.93,112.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation","uncharacterized LOC102724219","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724250,"'LOC102724250'",363.85,432.17,353.02,383.013333333333,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"neuroblastoma breakpoint family member 1","[NBPF1_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 1;+++[NBPF8_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 8;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFA_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 10;+++[NBPFB_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000305}; AltName: Full=Neuroblastoma breakpoint family member 24 {ECO:0000312|HGNC:HGNC:31993};+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFJ_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};"]
[102724378,"'LOC102724378'",3,4,2,3,{"$nulls":7},"uncharacterized LOC102724378"]
[102724428,"'SIK1B'",3396,3411,3620.16,3475.72,"04922///Glucagon signaling pathway","H00606///Early infantile epileptic encephalopathy+++H01819///Early myoclonic encephalopathy",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0032870///cellular response to hormone stimulus","salt inducible kinase 1B (putative)","[SIK1B_HUMAN|Reviewed]RecName: Full=Probable serine/threonine-protein kinase SIK1B {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:P57059, ECO:0000255|PROSITE-ProRule:PRU00159}; AltName: Full=Salt-inducible kinase 1B {ECO:0000305};+++[SIK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase SIK1; EC=2.7.11.1 {ECO:0000269|PubMed:14976552, ECO:0000269|PubMed:18348280}; AltName: Full=Salt-inducible kinase 1; Short=SIK-1; AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 1; Short=Serine/threonine-protein kinase SNF1LK;"]
[102724474,"'LOC102724474'",12,14,15,13.6666666666667,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0031233///intrinsic component of external side of plasma membrane","GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0051897///positive regulation of protein kinase B signaling+++GO:0030335///positive regulation of cell migration+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007596///blood coagulation+++GO:0007598///blood coagulation, extrinsic pathway","WAS/WASL-interacting protein family member 2-like","[FA10_BOVIN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_HUMAN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; AltName: Full=Stuart-Prower factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_MOUSE|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RABIT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RAT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;"]
[102724488,"'LOC102724488'",63.35,45.76,58.62,55.91,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0019905///syntaxin binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding+++GO:0030276///clathrin binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0006906///vesicle fusion+++GO:0017158///regulation of calcium ion-dependent exocytosis","synaptotagmin-15","[SYT15_HUMAN|Reviewed]RecName: Full=Synaptotagmin-15; AltName: Full=Chr10Syt; AltName: Full=Synaptotagmin XV; Short=SytXV;+++[A0A096LNH4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000478933}; Flags: Fragment;+++[X6R8R1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-15 {ECO:0000313|Ensembl:ENSP00000363443};"]
[102724560,"'CBSL'",212.73,258.19,127.99,199.636666666667,"01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00270///Cysteine and methionine metabolism+++00260///Glycine, serine and threonine metabolism+++01230///Biosynthesis of amino acids","H00183///Homocystinuria","M00035///Methionine degradation+++M00338///Cysteine biosynthesis, homocysteine + serine => cysteine","R01290///L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)   L-Serine + L-Homocysteine <=> L-Cystathionine + H2O+++R04942///L-Serine hydro-lyase (adding homocysteine)   L-Serine + Selenohomocysteine <=> L-Selenocystathionine + H2O+++R00891///L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)   L-Serine + Hydrogen sulfide <=> L-Cysteine + H2O","GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016829///lyase activity+++GO:0004122///cystathionine beta-synthase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0004124///cysteine synthase activity+++GO:0020037///heme binding","GO:0008652///cellular amino acid biosynthetic process+++GO:0019344///cysteine biosynthetic process+++GO:0006535///cysteine biosynthetic process from serine+++GO:0019346///transsulfuration+++GO:0019343///cysteine biosynthetic process via cystathionine+++GO:0070814///hydrogen sulfide biosynthetic process+++GO:0050667///homocysteine metabolic process","cystathionine-beta-synthase like","[CBS_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase {ECO:0000305}; EC=4.2.1.22 {ECO:0000269|PubMed:20506325, ECO:0000269|PubMed:23974653, ECO:0000269|PubMed:23981774, ECO:0000269|PubMed:25044645}; AltName: Full=Beta-thionase; AltName: Full=Serine sulfhydrase;+++[CBSL_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase-like protein {ECO:0000305}; EC=4.2.1.22 {ECO:0000250|UniProtKB:P35520}; AltName: Full=Beta-thionase {ECO:0000250|UniProtKB:P35520}; AltName: Full=Serine sulfhydrase {ECO:0000250|UniProtKB:P35520};"]
[102724594,"'U2AF1L5'",163.14,34.75,98.35,98.7466666666667,"05131///Shigellosis+++03040///Spliceosome","H01481///Myelodysplastic syndrome (MDS)",null,null,"GO:0089701///U2AF+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0046872///metal ion binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0003723///RNA binding+++GO:0050733///RS domain binding+++GO:0003676///nucleic acid binding","GO:0000398///mRNA splicing, via spliceosome","U2 small nuclear RNA auxiliary factor 1 like 5","[U2AF1_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit; AltName: Full=U2 auxiliary factor 35 kDa subunit; AltName: Full=U2 small nuclear RNA auxiliary factor 1; AltName: Full=U2 snRNP auxiliary factor small subunit;+++[U2AF5_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000305}; AltName: Full=U2 small nuclear RNA auxiliary factor 1-like protein 5 {ECO:0000312|HGNC:HGNC:51830};+++[A0A1B0GW87_HUMAN|Unreviewed]SubName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000313|Ensembl:ENSP00000490825};"]
[102724624,"'LOC102724624'",0.82,0,0,0.273333333333333,{"$nulls":7},"uncharacterized protein ENSP00000382042-like","[YQ018_HUMAN|diamond]RecName: Full=Uncharacterized protein ENSP00000382033;+++[YQ019_HUMAN|diamond]RecName: Full=Uncharacterized protein ENSP00000382042;"]
[102724642,"'LOC102724642'",3.43,0,0,1.14333333333333,"04111///Cell cycle - yeast+++04120///Ubiquitin mediated proteolysis+++04110///Cell cycle+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex+++GO:0005634///nucleus",null,"GO:0007049///cell cycle+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0051301///cell division","anaphase-promoting complex subunit 1-like","[APC1_CAEEL|diamond]RecName: Full=Anaphase-promoting complex subunit 1 {ECO:0000250|UniProtKB:Q9H1A4}; Short=APC1 {ECO:0000250|UniProtKB:Q9H1A4}; AltName: Full=Metaphase-to-anaphase transition protein 2 {ECO:0000312|WormBase:W10C6.1};+++[APC1_DICDI|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1;+++[APC1_HUMAN|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1; AltName: Full=Cyclosome subunit 1; AltName: Full=Mitotic checkpoint regulator; AltName: Full=Testis-specific gene 24 protein;+++[APC1_MOUSE|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1; AltName: Full=Cyclosome subunit 1; AltName: Full=Mitotic checkpoint regulator; AltName: Full=Testis-specific gene 24 protein;"]
[102724652,"'CRYAA2'",0,0,6,2,"04141///Protein processing in endoplasmic reticulum","H01202///Cataract",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050896///response to stimulus+++GO:0051260///protein homooligomerization+++GO:0032387///negative regulation of intracellular transport+++GO:0042026///protein refolding+++GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0007601///visual perception","crystallin alpha A2","[CRYA2_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A2 chain {ECO:0000305}; Contains: RecName: Full=Alpha-crystallin A2(1-172); Contains: RecName: Full=Alpha-crystallin A2(1-168); Contains: RecName: Full=Alpha-crystallin A2(1-162);+++[CRYAA_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A chain; AltName: Full=Heat shock protein beta-4; Short=HspB4; Contains: RecName: Full=Alpha-crystallin A(1-172); Contains: RecName: Full=Alpha-crystallin A(1-168); Contains: RecName: Full=Alpha-crystallin A(1-162);+++[A0A096LPJ9_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A2 chain {ECO:0000313|Ensembl:ENSP00000485653};+++[A0A140G952_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63592.1}; Flags: Fragment;+++[A0A140G954_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63594.1}; Flags: Fragment;+++[A0A140G955_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63595.1}; Flags: Fragment;+++[E7EWH7_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A chain {ECO:0000313|Ensembl:ENSP00000381201};+++[Q71V83_HUMAN|Unreviewed]SubName: Full=Alpha-A-crystallin {ECO:0000313|EMBL:AAB99912.1}; Flags: Fragment;"]
[102724720,"'LOC102724720'",1.99,0,0,0.663333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003839///gamma-glutamylcyclotransferase activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006750///glutathione biosynthetic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","uncharacterized LOC102724720","[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GGCT_HUMAN|diamond]RecName: Full=Gamma-glutamylcyclotransferase; EC=4.3.2.9; AltName: Full=Cytochrome c-releasing factor 21;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[102724751,"'LOC102724751'",84.19,79.59,69.56,77.78,"05200///Pathways in cancer+++05220///Chronic myeloid leukemia",{"$nulls":3},"GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0099092///postsynaptic density, intracellular component+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane","GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0050885///neuromuscular process controlling balance+++GO:0035023///regulation of Rho protein signal transduction+++GO:0071222///cellular response to lipopolysaccharide+++GO:0043314///negative regulation of neutrophil degranulation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050804///modulation of chemical synaptic transmission+++GO:0046777///protein autophosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0060268///negative regulation of respiratory burst+++GO:0002692///negative regulation of cellular extravasation+++GO:0065002///intracellular protein transmembrane transport+++GO:0050728///negative regulation of inflammatory response+++GO:0060313///negative regulation of blood vessel remodeling+++GO:0043547///positive regulation of GTPase activity+++GO:0050766///positive regulation of phagocytosis+++GO:0006468///protein phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0060216///definitive hemopoiesis+++GO:0051726///regulation of cell cycle+++GO:0043114///regulation of vascular permeability+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:0035556///intracellular signal transduction+++GO:0003014///renal system process+++GO:0048872///homeostasis of number of cells+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007420///brain development+++GO:0051171///regulation of nitrogen compound metabolic process","breakpoint cluster region protein-like","[ABR_BOVIN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_HUMAN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_MOUSE|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_XENTR|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[BCR_HUMAN|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1; AltName: Full=Renal carcinoma antigen NY-REN-26;+++[BCR_MOUSE|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1;"]
[102724770,"'LOC102724770'",278.36,304.38,237.28,273.34,"00330///Arginine and proline metabolism+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0031012///extracellular matrix+++GO:0005634///nucleus","GO:0004657///proline dehydrogenase activity","GO:0007155///cell adhesion+++GO:0009887///animal organ morphogenesis","protein DGCR6","[DGCR6_HUMAN|Reviewed]RecName: Full=Protein DGCR6; AltName: Full=DiGeorge syndrome critical region 6;+++[X5D7D2_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region 6 isoform D {ECO:0000313|EMBL:AHW56460.1}; Flags: Fragment;"]
[102724788,"'LOC102724788'",2223,3433.71,2878.7,2845.13666666667,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00330///Arginine and proline metabolism","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase   L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix","GO:0004657///proline dehydrogenase activity+++GO:0071949///FAD binding","GO:0019470///4-hydroxyproline catabolic process+++GO:0010133///proline catabolic process to glutamate+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0006562///proline catabolic process+++GO:0010942///positive regulation of cell death+++GO:0006560///proline metabolic process","proline dehydrogenase 1, mitochondrial","[PROD_BOVIN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000250|UniProtKB:O43272}; EC=1.5.5.2; AltName: Full=Proline oxidase {ECO:0000250|UniProtKB:O43272}; Flags: Precursor;+++[PROD_CAEEL|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;+++[PROD_DROME|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; AltName: Full=Protein sluggish-A; Flags: Precursor;+++[PROD_HUMAN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000305}; EC=1.5.5.2 {ECO:0000269|PubMed:15662599}; AltName: Full=Proline oxidase; AltName: Full=Proline oxidase 2; AltName: Full=p53-induced gene 6 protein; Flags: Precursor;+++[PROD_MOUSE|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;"]
[102724813,"'LOC102724813'",26,21.59,20,22.53,null,"H00591///Facioscapulohumeral muscular dystrophy (FSHD)",null,null,"GO:0015030///Cajal body+++GO:0005730///nucleolus+++GO:0030018///Z disc+++GO:0071013///catalytic step 2 spliceosome+++GO:0055120///striated muscle dense body","GO:0051015///actin filament binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006364///rRNA processing+++GO:0007517///muscle organ development","protein FRG1B","[FRG1_DROME|diamond]RecName: Full=Protein FRG1 homolog;+++[FRG1_HUMAN|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_MOUSE|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_TAKRU|diamond]RecName: Full=Protein FRG1;+++[FRG1_XENLA|diamond]RecName: Full=Protein FRG1 {ECO:0000250|UniProtKB:Q14331};"]
[102724843,"'LOC102724843'",405.75,393.27,331.18,376.733333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003677///DNA binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0006351///transcription, DNA-templated+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0043066///negative regulation of apoptotic process+++GO:0001933///negative regulation of protein phosphorylation","uncharacterized LOC102724843","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724862,"'TBC1D3I'",0,18.53,0,6.17666666666667,{"$nulls":4},"GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0031338///regulation of vesicle fusion+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3I","[TBC3I_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3I {ECO:0000312|HGNC:HGNC:32709};+++[A0A0B4J2F4_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3I {ECO:0000313|Ensembl:ENSP00000482914};"]
[102724951,"'LOC102724951'",108.73,107.48,52.7,89.6366666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005737///cytoplasm","GO:0004721///phosphoprotein phosphatase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0008284///positive regulation of cell proliferation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043066///negative regulation of apoptotic process","uncharacterized LOC102724951","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724965,"'LOC102724965'",0,2,0,0.666666666666667,{"$nulls":7},"uncharacterized LOC102724965","[A0A2Y9SDV6_PHYCD|diamond]SubName: Full=uncharacterized protein LOC102995166 {ECO:0000313|RefSeq:XP_023974475.1};"]
[102724984,"'LOC102724984'",3.1,3.61,4.55,3.75333333333333,{"$nulls":3},"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0030170///pyridoxal phosphate binding+++GO:0045296///cadherin binding+++GO:0016831///carboxy-lyase activity","GO:0019752///carboxylic acid metabolic process","KIAA2013 pseudogene","[K2013_BOVIN|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_HUMAN|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_MOUSE|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_XENLA|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_XENTR|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[PDXD1_BOVIN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_HUMAN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_MOUSE|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_XENLA|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD2_HUMAN|diamond]RecName: Full=Putative pyridoxal-dependent decarboxylase domain-containing protein 2; EC=4.1.1.-; AltName: Full=pyridoxal-dependent decarboxylase domain-containing 2 pseudogene;"]
[102724985,"'LOC102724985'",837.06,842.16,819.9,833.04,null,"H00542///Polycystic kidney disease+++H01728///Potter syndrome",null,"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0016328///lateral plasma membrane+++GO:0005654///nucleoplasm+++GO:0005929///cilium+++GO:0002133///polycystin complex+++GO:0016323///basolateral plasma membrane+++GO:0031514///motile cilium+++GO:0005887///integral component of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0060170///ciliary membrane+++GO:0030660///Golgi-associated vesicle membrane","GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0005262///calcium channel activity+++GO:0001042///RNA polymerase I core binding+++GO:0045296///cadherin binding+++GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0016831///carboxy-lyase activity+++GO:0044325///ion channel binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding","GO:0042254///ribosome biogenesis+++GO:0008344///adult locomotory behavior+++GO:0030010///establishment of cell polarity+++GO:0008283///cell proliferation+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0072177///mesonephric duct development+++GO:0007507///heart development+++GO:0021510///spinal cord development+++GO:0030155///regulation of cell adhesion+++GO:0006611///protein export from nucleus+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0021915///neural tube development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0072205///metanephric collecting duct development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043588///skin development+++GO:0048565///digestive tract development+++GO:0072164///mesonephric tubule development+++GO:0060236///regulation of mitotic spindle organization+++GO:0036303///lymph vessel morphogenesis+++GO:0001889///liver development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001502///cartilage condensation+++GO:0010976///positive regulation of neuron projection development+++GO:0051216///cartilage development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009653///anatomical structure morphogenesis+++GO:0034405///response to fluid shear stress+++GO:0007613///memory+++GO:0072237///metanephric proximal tubule development+++GO:0007160///cell-matrix adhesion+++GO:0019752///carboxylic acid metabolic process+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0007050///cell cycle arrest+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0001701///in utero embryonic development+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0070588///calcium ion transmembrane transport+++GO:0007259///JAK-STAT cascade+++GO:0048872///homeostasis of number of cells+++GO:0060674///placenta blood vessel development+++GO:0001822///kidney development+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007028///cytoplasm organization+++GO:0072218///metanephric ascending thin limb development+++GO:0001892///embryonic placenta development+++GO:0007000///nucleolus organization+++GO:0048806///genitalia development+++GO:0050982///detection of mechanical stimulus+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0060428///lung epithelium development+++GO:2000142///regulation of DNA-templated transcription, initiation+++GO:0032092///positive regulation of protein binding+++GO:0007204///positive regulation of cytosolic calcium ion concentration","pyridoxal-dependent decarboxylase domain-containing protein 1","[PDXD1_HUMAN|Reviewed]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[H3BND4_HUMAN|Unreviewed]SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000454791};+++[Q86XE2_HUMAN|Unreviewed]SubName: Full=PDXDC1 protein {ECO:0000313|EMBL:AAH45554.2}; SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000437835};"]
[102724993,"'LOC102724993'",528.92,630.72,624.46,594.7,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0002133///polycystin complex+++GO:0060170///ciliary membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016323///basolateral plasma membrane+++GO:0009986///cell surface+++GO:0000139///Golgi membrane+++GO:0031514///motile cilium+++GO:0030660///Golgi-associated vesicle membrane+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm","GO:0019901///protein kinase binding+++GO:0030246///carbohydrate binding+++GO:0005262///calcium channel activity+++GO:0019904///protein domain specific binding+++GO:0044325///ion channel binding","GO:0036303///lymph vessel morphogenesis+++GO:0048565///digestive tract development+++GO:0043588///skin development+++GO:0001502///cartilage condensation+++GO:0032092///positive regulation of protein binding+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0072177///mesonephric duct development+++GO:0060674///placenta blood vessel development+++GO:0051216///cartilage development+++GO:0072218///metanephric ascending thin limb development+++GO:0060428///lung epithelium development+++GO:0072237///metanephric proximal tubule development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0007259///JAK-STAT cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0001701///in utero embryonic development+++GO:0072164///mesonephric tubule development+++GO:0030010///establishment of cell polarity+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0021915///neural tube development+++GO:0001892///embryonic placenta development+++GO:0048806///genitalia development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0015031///protein transport+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0021510///spinal cord development+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072205///metanephric collecting duct development+++GO:0060236///regulation of mitotic spindle organization+++GO:0034405///response to fluid shear stress+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0001822///kidney development+++GO:0007160///cell-matrix adhesion+++GO:0007507///heart development+++GO:0030155///regulation of cell adhesion+++GO:0050982///detection of mechanical stimulus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0001889///liver development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0007050///cell cycle arrest","nuclear pore complex-interacting protein family member A7-like","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;+++[NPIA1_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A1; AltName: Full=Nuclear pore complex-interacting protein; Short=NPIP;+++[NPIA2_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A2;+++[NPIA3_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A3;+++[NPIA5_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[NPIA7_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[PKD1_HUMAN|diamond]RecName: Full=Polycystin-1; Short=PC1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein; Flags: Precursor;+++[PKD1_MOUSE|diamond]RecName: Full=Polycystin-1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein homolog; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[102725009,"'LOC102725009'",66.1,95.07,71.08,77.4166666666667,{"$nulls":4},"GO:0005764///lysosome","GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0007399///nervous system development+++GO:0001501///skeletal system development","putative inactive beta-glucuronidase-like protein SMA3","[BGLR_CHLAE|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor; Fragment;+++[BGLR_FELCA|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_HUMAN|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; AltName: Full=Beta-G1; Flags: Precursor;+++[BGLR_PONAB|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[GUSP1_HUMAN|diamond]RecName: Full=Putative inactive beta-glucuronidase-like protein SMA3;"]
[102725180,"'LOC102725180'",0,2,1,1,{"$nulls":7},"collagen alpha-1(VII) chain-like","[A0A0G2JWV7_RAT|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSRNOP00000070033};+++[A0A0G2K7V1_RAT|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSRNOP00000074358};+++[A0A0G2KXX0_DANRE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSDARP00000137304};+++[A0A2A9M6V0_9APIC|diamond]SubName: Full=SAG-related sequence {ECO:0000313|EMBL:PFH31616.1};+++[U3KI34_FICAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000014688};"]
[10273,"'STUB1'",1610,1535,1454,1533,"04141///Protein processing in endoplasmic reticulum+++04120///Ubiquitin mediated proteolysis","H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0000151///ubiquitin ligase complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0030018///Z disc+++GO:0101031///chaperone complex+++GO:0005829///cytosol+++GO:0042405///nuclear inclusion body+++GO:0031371///ubiquitin conjugating enzyme complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0031072///heat shock protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0048156///tau protein binding+++GO:0030674///protein binding, bridging+++GO:0004842///ubiquitin-protein transferase activity+++GO:0051087///chaperone binding+++GO:0042803///protein homodimerization activity+++GO:0051879///Hsp90 protein binding+++GO:0019899///enzyme binding+++GO:0046332///SMAD binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0051787///misfolded protein binding+++GO:0030911///TPR domain binding+++GO:0001664///G protein-coupled receptor binding+++GO:0030544///Hsp70 protein binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0019900///kinase binding","GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0061684///chaperone-mediated autophagy+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0051604///protein maturation+++GO:0032091///negative regulation of protein binding+++GO:0071456///cellular response to hypoxia+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0034605///cellular response to heat+++GO:0031398///positive regulation of protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031943///regulation of glucocorticoid metabolic process+++GO:0002931///response to ischemia+++GO:0006281///DNA repair+++GO:0038128///ERBB2 signaling pathway+++GO:0031647///regulation of protein stability+++GO:0030968///endoplasmic reticulum unfolded protein response","STIP1 homology and U-box containing protein 1","[CHIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:11557750, ECO:0000269|PubMed:15466472}; AltName: Full=Antigen NY-CO-7 {ECO:0000303|PubMed:9610721}; AltName: Full=CLL-associated antigen KW-8 {ECO:0000303|PubMed:12200376}; AltName: Full=Carboxy terminus of Hsp70-interacting protein {ECO:0000303|PubMed:10330192}; AltName: Full=RING-type E3 ubiquitin transferase CHIP {ECO:0000305}; AltName: Full=STIP1 homology and U box-containing protein 1 {ECO:0000312|HGNC:HGNC:11427};+++[H3BS86_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000456591}; Flags: Fragment;+++[H3BTA3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457090}; Flags: Fragment;+++[H3BUD0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457583}; Flags: Fragment;+++[V9GYH3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000476751}; Flags: Fragment;"]
[10274,"'STAG1'",384,329,321,344.666666666667,"04113///Meiosis - yeast+++04110///Cell cycle+++04111///Cell cycle - yeast","H00773///Autosomal dominant mental retardation",null,null,"GO:0016363///nuclear matrix+++GO:0097431///mitotic spindle pole+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000775///chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006351///transcription, DNA-templated+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1901673///regulation of mitotic spindle assembly+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division","stromal antigen 1","[STAG1_HUMAN|Reviewed]RecName: Full=Cohesin subunit SA-1; AltName: Full=SCC3 homolog 1; AltName: Full=Stromal antigen 1;+++[Q4LE48_HUMAN|Unreviewed]SubName: Full=STAG1 variant protein {ECO:0000313|EMBL:BAE06105.1}; Flags: Fragment;"]
[10276,"'NET1'",108,127,134,123,"04540///Gap junction+++04210///Apoptosis+++04530///Tight junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H00268///Lissencephaly (LIS)+++H00058///Amyotrophic lateral sclerosis (ALS)+++H00271///Polymicrogyria",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0005200///structural constituent of cytoskeleton+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0017049///GTP-Rho binding+++GO:0003924///GTPase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005525///GTP binding","GO:0035023///regulation of Rho protein signal transduction+++GO:0051451///myoblast migration+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0070301///cellular response to hydrogen peroxide+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0007017///microtubule-based process+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0001558///regulation of cell growth","neuroepithelial cell transforming 1","[ARHG8_HUMAN|Reviewed]RecName: Full=Neuroepithelial cell-transforming gene 1 protein; AltName: Full=Proto-oncogene p65 Net1; AltName: Full=Rho guanine nucleotide exchange factor 8;+++[Q5SQI5_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW86446.1}; SubName: Full=cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 protein {ECO:0000313|EMBL:BAG61338.1};+++[Q5SQI7_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_a {ECO:0000313|EMBL:EAW86445.1}; SubName: Full=cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA {ECO:0000313|EMBL:BAG37941.1};"]
[10277,"'UBE4B'",2103,2163,1953,2073,"04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0051117///ATPase binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0044257///cellular protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0051865///protein autoubiquitination+++GO:0034976///response to endoplasmic reticulum stress+++GO:0009411///response to UV+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0008626///granzyme-mediated apoptotic signaling pathway+++GO:0016567///protein ubiquitination+++GO:0006513///protein monoubiquitination+++GO:0031175///neuron projection development+++GO:0000209///protein polyubiquitination","ubiquitination factor E4B","[UBE4B_HUMAN|Reviewed]RecName: Full=Ubiquitin conjugation factor E4 B {ECO:0000305}; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q9ES00}; AltName: Full=Homozygously deleted in neuroblastoma 1 {ECO:0000312|EMBL:BAB40446.1}; AltName: Full=RING-type E3 ubiquitin transferase E4 B; AltName: Full=Ubiquitin fusion degradation protein 2 {ECO:0000312|EMBL:AAD02233.1};+++[B1AQ61_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000366358};+++[K7EP75_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000467258}; Flags: Fragment;+++[K7ERA7_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000468178}; Flags: Fragment;"]
[10278,"'EFS'",168,247,201,205.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0017124///SH3 domain binding","GO:0016477///cell migration+++GO:0035556///intracellular signal transduction+++GO:0090527///actin filament reorganization+++GO:0007155///cell adhesion","embryonal Fyn-associated substrate","[EFS_HUMAN|Reviewed]RecName: Full=Embryonal Fyn-associated substrate; Short=hEFS; AltName: Full=Cas scaffolding protein family member 3;"]
[10279,"'PRSS16'",22,30,31,27.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:0016020///membrane","GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis+++GO:0030163///protein catabolic process","serine protease 16","[TSSP_HUMAN|Reviewed]RecName: Full=Thymus-specific serine protease; EC=3.4.-.-; AltName: Full=Serine protease 16; Flags: Precursor;+++[B4DZV2_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000396589}; SubName: Full=cDNA FLJ52815, highly similar to Thymus-specific serine protease {ECO:0000313|EMBL:BAG64214.1};+++[C9JDN6_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419492};+++[F2Z2N5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000404349};+++[F8WBG5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418036};+++[F8WF25_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419437};+++[H0Y893_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418710}; Flags: Fragment;+++[H0Y8B9_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419538}; Flags: Fragment;"]
[1028,"'CDKN1C'",4204,5702,4654,4853.33333333333,"04110///Cell cycle","H01772///Adrenal hypoplasia congenita+++H00713///Beckwith-Wiedemann syndrome+++H00033///Adrenal carcinoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity","GO:0071514///genetic imprinting+++GO:0001501///skeletal system development+++GO:0035264///multicellular organism growth+++GO:0001822///kidney development+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0007049///cell cycle+++GO:0060065///uterus development+++GO:0007096///regulation of exit from mitosis+++GO:0033673///negative regulation of kinase activity+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0007050///cell cycle arrest+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042326///negative regulation of phosphorylation+++GO:0030099///myeloid cell differentiation+++GO:0055123///digestive system development+++GO:0043010///camera-type eye development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007568///aging+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0016310///phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001890///placenta development+++GO:0030325///adrenal gland development+++GO:0060669///embryonic placenta morphogenesis+++GO:0042551///neuron maturation+++GO:0007346///regulation of mitotic cell cycle","cyclin dependent kinase inhibitor 1C","[CDN1C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1C; AltName: Full=Cyclin-dependent kinase inhibitor p57; AltName: Full=p57Kip2;+++[A0A0G2JH30_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000321019};+++[A0A0G2JPX0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000484462};+++[A0A2R8YFP9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000496631};+++[A6NK88_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000370101};+++[B2D1N3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C transcript variant 3 {ECO:0000313|EMBL:ACB69757.1};"]
[10280,"'SIGMAR1'",3086,3206,3227,3173,null,"H00856///Distal hereditary motor neuropathies (dHMN)+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0016021///integral component of membrane+++GO:0005640///nuclear outer membrane+++GO:0030426///growth cone+++GO:0014069///postsynaptic density+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005811///lipid droplet+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0004985///opioid receptor activity+++GO:0008144///drug binding","GO:0006869///lipid transport+++GO:0036474///cell death in response to hydrogen peroxide+++GO:0038003///opioid receptor signaling pathway+++GO:0070207///protein homotrimerization+++GO:0007399///nervous system development+++GO:0043523///regulation of neuron apoptotic process","sigma non-opioid intracellular receptor 1","[SGMR1_HUMAN|Reviewed]RecName: Full=Sigma non-opioid intracellular receptor 1; AltName: Full=Aging-associated gene 8 protein; AltName: Full=SR31747-binding protein; Short=SR-BP; AltName: Full=Sigma 1-type opioid receptor; Short=SIG-1R; Short=Sigma1-receptor; Short=Sigma1R; Short=hSigmaR1;+++[A2A3U5_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_d {ECO:0000313|EMBL:EAW58436.1}; SubName: Full=cDNA FLJ76396, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83781.1};+++[B4DR71_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57078, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61183.1};+++[Q5T1J1_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_c {ECO:0000313|EMBL:EAW58433.1}; SubName: Full=Sigma non-opioid intracellular receptor 1 {ECO:0000313|Ensembl:ENSP00000368170};"]
[102800317,"'TPTEP2-CSNK1E'",107.1,152.23,165.25,141.526666666667,"04068///FoxO signaling pathway+++04711///Circadian rhythm - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species+++04710///Circadian rhythm+++04310///Wnt signaling pathway+++04391///Hippo signaling pathway - fly+++04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042752///regulation of circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0008360///regulation of cell shape+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway+++GO:0006281///DNA repair+++GO:0007165///signal transduction+++GO:0032197///transposition, RNA-mediated+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0006468///protein phosphorylation+++GO:1903827///regulation of cellular protein localization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1905426///positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation+++GO:0006897///endocytosis+++GO:0060070///canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006310///DNA recombination+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle","TPTEP2-CSNK1E readthrough","[KC1E_HUMAN|Reviewed]RecName: Full=Casein kinase I isoform epsilon; Short=CKI-epsilon; Short=CKIe; EC=2.7.11.1;+++[B3KRV2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34950 fis, clone NT2RP7017284, highly similar to Casein kinase I isoform epsilon {ECO:0000313|EMBL:BAG52514.1};+++[Q5U045_HUMAN|Unreviewed]SubName: Full=Casein kinase 1 epsilon {ECO:0000313|EMBL:ABM64212.1}; SubName: Full=Casein kinase 1, epsilon {ECO:0000313|EMBL:AAV38634.1}; SubName: Full=HCG2014051, isoform CRA_a {ECO:0000313|EMBL:EAW60228.1};"]
[10282,"'BET1'",114,110,96,106.666666666667,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0030173///integral component of Golgi membrane","GO:0005515///protein binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","Bet1 golgi vesicular membrane trafficking protein","[BET1_HUMAN|Reviewed]RecName: Full=BET1 homolog; Short=hBET1; AltName: Full=Golgi vesicular membrane-trafficking protein p18;+++[C9JTT8_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000413063};+++[H7C1N3_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000401260}; Flags: Fragment;+++[Q53XK0_HUMAN|Unreviewed]SubName: Full=BET1 homolog (S. cerevisiae) {ECO:0000313|EMBL:AAP88855.1}; SubName: Full=BET1 homolog (S. cerevisiae), isoform CRA_d {ECO:0000313|EMBL:EAW76803.1}; SubName: Full=cDNA, FLJ94635, Homo sapiens BET1 homolog (S. cerevisiae) (BET1), mRNA {ECO:0000313|EMBL:BAG36696.1};+++[Q68DU7_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000350125};"]
[10283,"'CWC27'",334,292,281,302.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0071012///catalytic step 1 spliceosome","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding","GO:0000413///protein peptidyl-prolyl isomerization+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006457///protein folding","CWC27 spliceosome associated protein homolog","[CWC27_HUMAN|Reviewed]RecName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000305}; AltName: Full=Antigen NY-CO-10 {ECO:0000303|PubMed:9610721}; AltName: Full=Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog {ECO:0000305|PubMed:20676357}; Short=PPIase CWC27 {ECO:0000305|PubMed:20676357}; AltName: Full=Serologically defined colon cancer antigen 10;+++[D6REK3_HUMAN|Unreviewed]SubName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000313|Ensembl:ENSP00000426802};"]
[10284,"'SAP18'",1110,1132,954,1065.33333333333,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0000118///histone deacetylase complex+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0061574///ASAP complex","GO:0004407///histone deacetylase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity","GO:0008380///RNA splicing+++GO:0043065///positive regulation of apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0048025///negative regulation of mRNA splicing, via spliceosome","Sin3A associated protein 18","[SAP18_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP18; AltName: Full=18 kDa Sin3-associated polypeptide; AltName: Full=2HOR0202; AltName: Full=Cell growth-inhibiting gene 38 protein; AltName: Full=Sin3-associated polypeptide p18;+++[H7BZW6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000391846}; Flags: Fragment;+++[U3KPY7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475358}; Flags: Fragment;+++[U3KQ12_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475435}; Flags: Fragment;+++[X6RAL5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000371973};"]
[10285,"'SMNDC1'",273,229,220,240.666666666667,"03040///Spliceosome",{"$nulls":3},"GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0008380///RNA splicing+++GO:0006915///apoptotic process","survival motor neuron domain containing 1","[SPF30_HUMAN|Reviewed]RecName: Full=Survival of motor neuron-related-splicing factor 30; AltName: Full=30 kDa splicing factor SMNrp; AltName: Full=SMN-related protein; AltName: Full=Survival motor neuron domain-containing protein 1;"]
[10286,"'BCAS2'",357,380,330,355.666666666667,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005634///nucleus+++GO:0000974///Prp19 complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005813///centrosome+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005730///nucleolus","GO:0005515///protein binding","GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000375///RNA splicing, via transesterification reactions","BCAS2, pre-mRNA processing factor","[SPF27_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SPF27; AltName: Full=Breast carcinoma-amplified sequence 2; AltName: Full=DNA amplified in mammary carcinoma 1 protein; AltName: Full=Spliceosome-associated protein SPF 27;+++[B2R7W3_HUMAN|Unreviewed]SubName: Full=Breast carcinoma amplified sequence 2 {ECO:0000313|EMBL:BAG70059.1}; SubName: Full=Breast carcinoma amplified sequence 2, isoform CRA_a {ECO:0000313|EMBL:EAW56602.1}; SubName: Full=cDNA, FLJ93631, Homo sapiens breast carcinoma amplified sequence 2 (BCAS2), mRNA {ECO:0000313|EMBL:BAG35960.1};"]
[10287,"'RGS19'",170,145,155,156.666666666667,{"$nulls":4},"GO:0005903///brush border+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030136///clathrin-coated vesicle","GO:0001965///G-protein alpha-subunit binding+++GO:0005515///protein binding","GO:0007264///small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0045471///response to ethanol+++GO:0006914///autophagy","regulator of G protein signaling 19","[RGS19_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 19; Short=RGS19; AltName: Full=G-alpha-interacting protein; Short=GAIP;+++[B4DP94_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59828, highly similar to Regulator of G-protein signaling 19 {ECO:0000313|EMBL:BAG60506.1};+++[Q6I9S5_HUMAN|Unreviewed]SubName: Full=RGS19 protein {ECO:0000313|EMBL:CAG33711.1};+++[Q9H2T9_HUMAN|Unreviewed]SubName: Full=G alpha interacting protein {ECO:0000313|EMBL:AAG42352.1}; Flags: Fragment;"]
[10289,"'EIF1B'",489,426,428,447.666666666667,"03013///RNA transport",{"$nulls":3},"GO:0005575///cellular_component+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0043024///ribosomal small subunit binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006446///regulation of translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation","eukaryotic translation initiation factor 1B","[EIF1B_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1b; Short=eIF1b; AltName: Full=Protein translation factor SUI1 homolog GC20;+++[Q6FG85_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1B, isoform CRA_a {ECO:0000313|EMBL:EAW64598.1}; SubName: Full=GC20 protein {ECO:0000313|EMBL:CAG47019.1}; SubName: Full=cDNA, FLJ92189, Homo sapiens translation factor sui1 homolog (GC20), mRNA {ECO:0000313|EMBL:BAG34863.1}; Flags: Fragment;"]
[1029,"'CDKN2A'",7219,6476,7364,7019.66666666667,"04934///Cushing's syndrome+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++01524///Platinum drug resistance+++05214///Glioma+++05223///Non-small cell lung cancer+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05163///Human cytomegalovirus infection+++05212///Pancreatic cancer+++04218///Cellular senescence+++05219///Bladder cancer+++04110///Cell cycle+++05166///HTLV-I infection+++01522///Endocrine resistance+++05218///Melanoma+++05200///Pathways in cancer","H01513///Retinoblastoma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00054///Nasopharyngeal cancer+++H01556///Meningioma+++H00015///Malignant pleural mesothelioma+++H00042///Glioma+++H00008///Burkitt lymphoma+++H00040///Squamous cell carcinoma+++H00009///Adult T-cell leukemia+++H00017///Esophageal cancer+++H00014///Non-small cell lung cancer+++H00025///Penile cancer+++H00004///Chronic myeloid leukemia (CML)+++H00016///Oral cancer+++H01509///Tonsillar cancer+++H01464///Mantle cell lymphoma+++H00055///Laryngeal cancer+++H00047///Gallbladder cancer+++H00048///Hepatocellular carcinoma+++H01508///Salivary gland cancer+++H00046///Cholangiocarcinoma+++H00409///Type II diabetes mellitus+++H00038///Melanoma+++H00022///Bladder cancer+++H00019///Pancreatic cancer",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035985///senescence-associated heterochromatin focus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0003723///RNA binding+++GO:0055105///ubiquitin-protein transferase inhibitor activity+++GO:0097718///disordered domain specific binding+++GO:0019901///protein kinase binding+++GO:0051059///NF-kappaB binding+++GO:1990948///ubiquitin ligase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0003677///DNA binding+++GO:0002039///p53 binding+++GO:0019789///SUMO transferase activity+++GO:0016301///kinase activity","GO:0050821///protein stabilization+++GO:0090399///replicative senescence+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0033235///positive regulation of protein sumoylation+++GO:0042326///negative regulation of phosphorylation+++GO:0000422///autophagy of mitochondrion+++GO:0046825///regulation of protein export from nucleus+++GO:0030889///negative regulation of B cell proliferation+++GO:0000209///protein polyubiquitination+++GO:2000435///negative regulation of protein neddylation+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0016925///protein sumoylation+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007265///Ras protein signal transduction+++GO:0007050///cell cycle arrest+++GO:0051882///mitochondrial depolarization+++GO:0071158///positive regulation of cell cycle arrest+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0031648///protein destabilization+++GO:0016310///phosphorylation+++GO:0008637///apoptotic mitochondrial changes+++GO:0048103///somatic stem cell division+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0090398///cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0030308///negative regulation of cell growth+++GO:1902510///regulation of apoptotic DNA fragmentation+++GO:0006469///negative regulation of protein kinase activity+++GO:0070534///protein K63-linked ubiquitination+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:1903051///negative regulation of proteolysis involved in cellular protein catabolic process+++GO:2000774///positive regulation of cellular senescence+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006915///apoptotic process+++GO:1990000///amyloid fibril formation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0031647///regulation of protein stability+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:2000111///positive regulation of macrophage apoptotic process+++GO:0006364///rRNA processing+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","cyclin dependent kinase inhibitor 2A","[ARF_HUMAN|Reviewed]RecName: Full=Tumor suppressor ARF {ECO:0000305}; AltName: Full=Alternative reading frame {ECO:0000303|PubMed:9724636}; Short=ARF {ECO:0000303|PubMed:9724636}; AltName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=p14ARF {ECO:0000303|PubMed:9724636};+++[CDN2A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=Cyclin-dependent kinase 4 inhibitor A; Short=CDK4I; AltName: Full=Multiple tumor suppressor 1; Short=MTS-1; AltName: Full=p16-INK4a; Short=p16-INK4; Short=p16INK4A;+++[A7LNE7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:ABS32187.1}; Flags: Fragment;+++[D1LYX3_HUMAN|Unreviewed]SubName: Full=Truncated tumor suppressor protein P16 {ECO:0000313|EMBL:ACY78326.1};+++[J3QRG6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000464202};+++[K7ENC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000466887};+++[K7ES20_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000468510};+++[K7PML8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AFN61600.1};+++[L8E941_HUMAN|Unreviewed]SubName: Full=Alternative protein CDKN2A {ECO:0000313|EMBL:CCQ43815.1};+++[Q208B5_HUMAN|Unreviewed]SubName: Full=p16 {ECO:0000313|EMBL:ABD72255.1}; Flags: Fragment;+++[Q2MJK0_HUMAN|Unreviewed]SubName: Full=p16 protein {ECO:0000313|EMBL:ABC50001.1}; Flags: Fragment;+++[Q5ZEY9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:CAH59950.1}; Flags: Fragment;+++[Q9UPB7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AAD02319.1}; Flags: Fragment;"]
[10290,"'SPEG'",2513,2280,2393,2395.33333333333,null,"H00700///Centronuclear myopathy",null,null,"GO:0005634///nucleus","GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0072358///cardiovascular system development+++GO:0030154///cell differentiation+++GO:0016310///phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0042692///muscle cell differentiation+++GO:0007517///muscle organ development","SPEG complex locus","[SPEG_HUMAN|Reviewed]RecName: Full=Striated muscle preferentially expressed protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[B9ZVR7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000379926};+++[C9J8D8_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000410986}; Flags: Fragment;+++[C9JWU5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000393134}; Flags: Fragment;+++[F8WCA7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000406530};+++[G5E9J7_HUMAN|Unreviewed]SubName: Full=Aortic preferentially expressed gene 1, isoform CRA_i {ECO:0000313|EMBL:EAW70750.1}; SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000397514};+++[H0Y3W0_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000387344}; Flags: Fragment;+++[H7BZM6_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000390353}; Flags: Fragment;+++[H7C3Y5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000414549}; Flags: Fragment;"]
[10291,"'SF3A1'",3470,4003,3637,3703.33333333333,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0005684///U2-type spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005686///U2 snRNP+++GO:0071004///U2-type prespliceosome+++GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000389///mRNA 3'-splice site recognition","splicing factor 3a subunit 1","[SF3A1_HUMAN|Reviewed]RecName: Full=Splicing factor 3A subunit 1; AltName: Full=SF3a120; AltName: Full=Spliceosome-associated protein 114; Short=SAP 114;+++[A0A024R1K8_HUMAN|Unreviewed]SubName: Full=Splicing factor 3a, subunit 1, 120kDa, isoform CRA_a {ECO:0000313|EMBL:EAW59879.1};+++[F8WB66_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000397267};+++[F8WC79_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000412715};+++[H7C1L2_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000400862}; Flags: Fragment;"]
[10293,"'TRAIP'",34,42,31,35.6666666666667,null,"H00992///Seckel syndrome",null,null,"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0016567///protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0008283///cell proliferation+++GO:0032688///negative regulation of interferon-beta production+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway","TRAF interacting protein","[TRAIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRAIP; EC=2.3.2.27; AltName: Full=RING finger protein 206; AltName: Full=RING-type E3 ubiquitin transferase TRAIP {ECO:0000305}; AltName: Full=TRAF-interacting protein;+++[E7EN91_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000418544}; Flags: Fragment;+++[E7ETV1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000420085};+++[E7EVC4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419556};+++[E7EW89_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419350}; Flags: Fragment;"]
[10294,"'DNAJA2'",785,775,775,778.333333333333,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0001671///ATPase activator activity+++GO:0031072///heat shock protein binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006457///protein folding+++GO:0042026///protein refolding+++GO:0008284///positive regulation of cell proliferation+++GO:0009408///response to heat+++GO:0032781///positive regulation of ATPase activity","DnaJ heat shock protein family (Hsp40) member A2","[DNJA2_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily A member 2; AltName: Full=Cell cycle progression restoration gene 3 protein; AltName: Full=Dnj3; Short=Dj3; AltName: Full=HIRA-interacting protein 4; AltName: Full=Renal carcinoma antigen NY-REN-14; Flags: Precursor;+++[A0A024R6S1_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily A, member 2, isoform CRA_a {ECO:0000313|EMBL:EAW82694.1};+++[A0A087WT48_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000477579}; Flags: Fragment;+++[I3L320_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000460104};"]
[10295,"'BCKDK'",2168,2015,1976,2053,null,"H02136///Branched-chain ketoacid dehydrogenase kinase deficiency",null,null,"GO:0005947///mitochondrial alpha-ketoglutarate dehydrogenase complex+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0047323///[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0009083///branched-chain amino acid catabolic process+++GO:0009063///cellular amino acid catabolic process","branched chain ketoacid dehydrogenase kinase","[BCKD_HUMAN|Reviewed]RecName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; EC=2.7.11.4; AltName: Full=Branched-chain alpha-ketoacid dehydrogenase kinase; Short=BCKD-kinase; Short=BCKDHKIN; Flags: Precursor;+++[A0A024QZA9_HUMAN|Unreviewed]SubName: Full=Branched chain ketoacid dehydrogenase kinase, isoform CRA_b {ECO:0000313|EMBL:EAW52162.1};+++[H3BNP3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000454947}; Flags: Fragment;+++[H3BQP2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000455866}; Flags: Fragment;+++[H3BS02_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456479};+++[H3BTL2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457226}; Flags: Fragment;+++[H3BUV3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457821}; Flags: Fragment;"]
[10296,"'MAEA'",1204,1205,1098,1169,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0034657///GID complex+++GO:0005826///actomyosin contractile ring+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix","GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0003779///actin binding","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045721///negative regulation of gluconeogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048821///erythrocyte development+++GO:0043249///erythrocyte maturation+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0048822///enucleate erythrocyte development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007155///cell adhesion","macrophage erythroblast attacher","[MAEA_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein transferase MAEA; EC=2.3.2.27 {ECO:0000269|PubMed:29911972}; AltName: Full=Cell proliferation-inducing gene 5 protein {ECO:0000303|Ref.1}; AltName: Full=Erythroblast macrophage protein {ECO:0000303|PubMed:9763581}; AltName: Full=Human lung cancer oncogene 10 protein; Short=HLC-10; AltName: Full=Macrophage erythroblast attacher; AltName: Full=P44EMLP {ECO:0000303|PubMed:17467196};+++[B3KRN7_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_c {ECO:0000313|EMBL:EAW82589.1}; SubName: Full=cDNA FLJ34632 fis, clone KIDNE2015660, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG52449.1};+++[B4DJP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54833, moderately similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG58910.1};+++[B4DQT1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000424436}; SubName: Full=cDNA FLJ53639, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61043.1};+++[B4DVN3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000426807}; SubName: Full=cDNA FLJ54556, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62745.1};+++[D3DVP1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_b {ECO:0000313|EMBL:EAW82591.1};+++[D3DVP3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_a {ECO:0000313|EMBL:EAW82588.1};+++[D3DVP6_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_d {ECO:0000313|EMBL:EAW82592.1};+++[D6R8Z3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422235};+++[D6RA86_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000423056};+++[D6RDW4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426966};+++[D6RE80_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426903}; Flags: Fragment;+++[D6REW7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000421644}; Flags: Fragment;+++[D6RIB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427512};+++[D6RID6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427460}; Flags: Fragment;+++[E7ESC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422215};"]
[10297,"'APC2'",1961,3704,2720,2795,"05224///Breast cancer+++04390///Hippo signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05213///Endometrial cancer+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04810///Regulation of actin cytoskeleton+++05206///MicroRNAs in cancer+++04310///Wnt signaling pathway+++05165///Human papillomavirus infection+++05166///HTLV-I infection+++04550///Signaling pathways regulating pluripotency of stem cells+++05210///Colorectal cancer+++05225///Hepatocellular carcinoma","H02049///Bilateral macronodular adrenal hyperplasia (BMAH)+++H00017///Esophageal cancer+++H00020///Colorectal cancer+++H00044///Cancer of the anal canal+++H01431///Cushing's syndrome+++H01667///Medulloblastoma+++H01025///Familial adenomatous polyposis+++H00018///Gastric cancer+++H00047///Gallbladder cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030496///midbody+++GO:0015630///microtubule cytoskeleton+++GO:0031258///lamellipodium membrane+++GO:0005884///actin filament+++GO:0045171///intercellular bridge+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0016342///catenin complex+++GO:0016020///membrane","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0008017///microtubule binding+++GO:0008013///beta-catenin binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0090630///activation of GTPase activity+++GO:0006413///translational initiation+++GO:0000226///microtubule cytoskeleton organization+++GO:0006364///rRNA processing+++GO:0001649///osteoblast differentiation+++GO:0016055///Wnt signaling pathway+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0042274///ribosomal small subunit biogenesis","APC2, WNT signaling pathway regulator","[APCL_HUMAN|Reviewed]RecName: Full=Adenomatous polyposis coli protein 2; AltName: Full=Adenomatous polyposis coli protein-like; Short=APC-like;"]
[10298,"'PAK4'",4588,5475,4689,4917.33333333333,"04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++04012///ErbB signaling pathway+++04360///Axon guidance+++04660///T cell receptor signaling pathway+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005925///focal adhesion+++GO:0005913///cell-cell adherens junction+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0048365///Rac GTPase binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045766///positive regulation of angiogenesis+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0001558///regulation of cell growth+++GO:0006915///apoptotic process+++GO:0006468///protein phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0071407///cellular response to organic cyclic compound+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0060996///dendritic spine development+++GO:0023014///signal transduction by protein phosphorylation+++GO:0098609///cell-cell adhesion+++GO:0016477///cell migration+++GO:0043408///regulation of MAPK cascade+++GO:0016310///phosphorylation","p21 (RAC1) activated kinase 4","[PAK4_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 4; EC=2.7.11.1; AltName: Full=p21-activated kinase 4; Short=PAK-4;+++[A0A024R0J1_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[A0A024R0L8_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[B4DUG0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61413, highly similar to Serine/threonine-protein kinase PAK 4 {ECO:0000313|EMBL:BAG62322.1}; SubName: Full=p21(CDKN1A)-activated kinase 4, isoform CRA_e {ECO:0000313|EMBL:EAW56865.1};+++[M0R0L9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000471318}; Flags: Fragment;+++[M0R1R1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472061}; Flags: Fragment;+++[M0R2X4_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472862}; Flags: Fragment;+++[M0R3G6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000473215}; Flags: Fragment;"]
[10299,"'MARCH6'",1641,1629,1443,1571,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0000835///ER ubiquitin ligase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0008270///zinc ion binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0061630///ubiquitin protein ligase activity","GO:0016567///protein ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0010498///proteasomal protein catabolic process+++GO:0036503///ERAD pathway+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:1904380///endoplasmic reticulum mannose trimming","membrane associated ring-CH-type finger 6","[MARH6_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MARCH6; EC=2.3.2.27; AltName: Full=Doa10 homolog; AltName: Full=Membrane-associated RING finger protein 6; AltName: Full=Membrane-associated RING-CH protein VI; Short=MARCH-VI; AltName: Full=Protein TEB-4; AltName: Full=RING finger protein 176; AltName: Full=RING-type E3 ubiquitin transferase MARCH6 {ECO:0000305};+++[A0A0B4J206_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000424512};+++[D6RHY7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000426000};"]
[103,"'ADAR'",3026,3549,3179,3251.33333333333,"05162///Measles+++05164///Influenza A+++04623///Cytosolic DNA-sensing pathway","H00880///Dyschromatosis symmetrica hereditaria",null,null,"GO:0005634///nucleus+++GO:0044530///supraspliceosomal complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0003677///DNA binding+++GO:0003725///double-stranded RNA binding","GO:0006397///mRNA processing+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0016553///base conversion or substitution editing+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0006611///protein export from nucleus+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006396///RNA processing+++GO:0006606///protein import into nucleus+++GO:0006382///adenosine to inosine editing+++GO:0009615///response to virus+++GO:0035455///response to interferon-alpha+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060337///type I interferon signaling pathway+++GO:0031054///pre-miRNA processing+++GO:0031047///gene silencing by RNA","adenosine deaminase, RNA specific","[DSRAD_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific adenosine deaminase; Short=DRADA {ECO:0000303|PubMed:7972084}; EC=3.5.4.37 {ECO:0000269|PubMed:7565688, ECO:0000269|PubMed:7972084}; AltName: Full=136 kDa double-stranded RNA-binding protein; Short=p136; AltName: Full=Interferon-inducible protein 4; Short=IFI-4; AltName: Full=K88DSRBP;+++[A2IBT1_HUMAN|Unreviewed]SubName: Full=Truncated adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73519.1};+++[A2IBT2_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73520.1}; Flags: Fragment;+++[D3DV75_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase, RNA-specific, isoform CRA_b {ECO:0000313|EMBL:EAW53189.1};+++[H0YCK3_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific adenosine deaminase {ECO:0000313|Ensembl:ENSP00000431794}; Flags: Fragment;"]
[1030,"'CDKN2B'",3977,3119,3651,3582.33333333333,"04934///Cushing's syndrome+++04110///Cell cycle+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05166///HTLV-I infection+++04068///FoxO signaling pathway+++05226///Gastric cancer+++05222///Small cell lung cancer+++04350///TGF-beta signaling pathway+++04218///Cellular senescence","H00015///Malignant pleural mesothelioma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00409///Type II diabetes mellitus+++H01556///Meningioma",null,null,"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0016301///kinase activity","GO:0030219///megakaryocyte differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0031668///cellular response to extracellular stimulus+++GO:0016310///phosphorylation+++GO:0090398///cellular senescence+++GO:0007093///mitotic cell cycle checkpoint+++GO:0008285///negative regulation of cell proliferation+++GO:0048536///spleen development+++GO:0031670///cellular response to nutrient+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0042326///negative regulation of phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway","cyclin dependent kinase inhibitor 2B","[CDN2B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor B; AltName: Full=Multiple tumor suppressor 2; Short=MTS-2; AltName: Full=p14-INK4b; AltName: Full=p15-INK4b; Short=p15INK4B;+++[K7PPU3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AFN61601.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4), isoform CRA_b {ECO:0000313|EMBL:EAW58597.1}; SubName: Full=p15 {ECO:0000313|EMBL:AGC10270.1};+++[Q5ZEY8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:CAH59951.1};+++[Q8NIA6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AAF28397.1}; Flags: Fragment;"]
[10300,"'KATNB1'",671,786,764,740.333333333333,null,"H00268///Lissencephaly (LIS)",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0030426///growth cone+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0030496///midbody+++GO:0005819///spindle+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0008352///katanin complex+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0030424///axon","GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0070840///dynein complex binding","GO:0051301///cell division+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0010942///positive regulation of cell death+++GO:0007019///microtubule depolymerization+++GO:0007049///cell cycle+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0051013///microtubule severing+++GO:0006605///protein targeting+++GO:0010976///positive regulation of neuron projection development","katanin regulatory subunit B1","[KTNB1_HUMAN|Reviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000255|HAMAP-Rule:MF_03022};+++[A0A024R6U1_HUMAN|Unreviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000256|HAMAP-Rule:MF_03022};+++[H3BPD8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455270}; Flags: Fragment;+++[H3BPK1_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455350}; Flags: Fragment;+++[H3BT67_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457046}; Flags: Fragment;+++[H3BTU7_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457334}; Flags: Fragment;+++[H3BTV8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457347}; Flags: Fragment;"]
[10302,"'SNAPC5'",157,146,132,145,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0006355///regulation of transcription, DNA-templated","small nuclear RNA activating complex polypeptide 5","[SNPC5_HUMAN|Reviewed]RecName: Full=snRNA-activating protein complex subunit 5; Short=SNAPc subunit 5; AltName: Full=Small nuclear RNA-activating complex polypeptide 5; AltName: Full=snRNA-activating protein complex 19 kDa subunit; Short=SNAPc 19 kDa subunit;+++[A0A024R5X1_HUMAN|Unreviewed]SubName: Full=Small nuclear RNA activating complex, polypeptide 5, 19kDa, isoform CRA_a {ECO:0000313|EMBL:EAW77772.1};+++[H3BQA0_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000455680};+++[H3BSI3_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000456716};"]
[10307,"'APBB3'",177,238,202,205.666666666667,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated","amyloid beta precursor protein binding family B member 3","[APBB3_HUMAN|Reviewed]RecName: Full=Amyloid-beta A4 precursor protein-binding family B member 3; AltName: Full=Protein Fe65-like 2; Short=Fe65L2;+++[B3KQG2_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3, isoform CRA_b {ECO:0000313|EMBL:EAW62042.1}; SubName: Full=cDNA FLJ43254 fis, clone HEART2008108, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG54172.1}; SubName: Full=cDNA FLJ90404 fis, clone NT2RP2006092, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG52024.1};+++[D6RBA1_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000424317};+++[D6RJB2_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000427272};+++[E7EX91_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000351389};+++[Q59EH2_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein-binding, family B, member 3 isoform b variant {ECO:0000313|EMBL:BAD93076.1}; Flags: Fragment;+++[Q86Z13_HUMAN|Unreviewed]SubName: Full=Fe65L2 isoform 339 {ECO:0000313|EMBL:BAC56948.1};+++[Q96DX9_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3 {ECO:0000313|EMBL:AAH13158.1};"]
[10308,"'ZNF267'",94,70,70,78,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 267","[ZN267_HUMAN|Reviewed]RecName: Full=Zinc finger protein 267; AltName: Full=Zinc finger protein HZF2;+++[H3BMG2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454369}; Flags: Fragment;+++[H3BNA3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454753}; Flags: Fragment;+++[H3BPW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000455493}; Flags: Fragment;+++[I3L4I6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000461286};"]
[10309,"'CCNO'",494,445,457,465.333333333333,null,"H00564///Primary ciliary dyskinesia",null,null,"GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity","GO:0045787///positive regulation of cell cycle+++GO:0060271///cilium assembly+++GO:0000278///mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042493///response to drug+++GO:1903251///multi-ciliated epithelial cell differentiation+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0006468///protein phosphorylation+++GO:0030030///cell projection organization+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division","cyclin O","[CCNO_HUMAN|Reviewed]RecName: Full=Cyclin-O;"]
[1031,"'CDKN2C'",9,6,5,6.66666666666667,"01522///Endocrine resistance+++04934///Cushing's syndrome+++04110///Cell cycle+++05202///Transcriptional misregulation in cancer+++05166///HTLV-I infection",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0019901///protein kinase binding","GO:0016310///phosphorylation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0042326///negative regulation of phosphorylation+++GO:0007049///cell cycle+++GO:0048709///oligodendrocyte differentiation+++GO:0007050///cell cycle arrest+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0008285///negative regulation of cell proliferation","cyclin dependent kinase inhibitor 2C","[CDN2C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor C; AltName: Full=Cyclin-dependent kinase 6 inhibitor; AltName: Full=p18-INK4c; AltName: Full=p18-INK6;+++[Q6ICV4_HUMAN|Unreviewed]SubName: Full=CDKN2C protein {ECO:0000313|EMBL:CAG29285.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2C (P18, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAX06833.1}; SubName: Full=cDNA FLJ33851 fis, clone CTONG2005635, highly similar to CYCLIN-DEPENDENT KINASE 6 INHIBITOR {ECO:0000313|EMBL:BAG52297.1}; Flags: Fragment;+++[Q9P1T2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2C {ECO:0000313|EMBL:AAF28398.1}; Flags: Fragment;"]
[10311,"'VPS26C'",529.01,496,483,502.67,{"$nulls":4},"GO:0005768///endosome+++GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0008565///protein transporter activity","GO:0008150///biological_process+++GO:0006886///intracellular protein transport","VPS26 endosomal protein sorting factor C","[DSCR3_HUMAN|Reviewed]RecName: Full=Down syndrome critical region protein 3; AltName: Full=Down syndrome critical region protein A;+++[A8MTY9_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381964};+++[A8MY26_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381967}; SubName: Full=cDNA FLJ53689, highly similar to Down syndrome critical region protein 3 {ECO:0000313|EMBL:BAH14000.1};"]
[10312,"'TCIRG1'",917,921,905,914.333333333333,"04721///Synaptic vesicle cycle+++05323///Rheumatoid arthritis+++05152///Tuberculosis+++04145///Phagosome+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04142///Lysosome+++00190///Oxidative phosphorylation+++04966///Collecting duct acid secretion+++01100///Metabolic pathways+++05110///Vibrio cholerae infection+++05165///Human papillomavirus infection","H00557///Cutis laxa+++H00428///Distal renal tubular acidosis (RTA type 1)+++H00436///Osteopetrosis","M00160///V-type ATPase, eukaryotes",null,"GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0005886///plasma membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030670///phagocytic vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0010008///endosome membrane+++GO:0005765///lysosomal membrane","GO:0051117///ATPase binding+++GO:0005215///transporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism","GO:0007035///vacuolar acidification+++GO:0006811///ion transport+++GO:0016236///macroautophagy+++GO:1902600///proton transmembrane transport+++GO:0006968///cellular defense response+++GO:0033572///transferrin transport+++GO:0034220///ion transmembrane transport+++GO:0007039///protein catabolic process in the vacuole+++GO:0043312///neutrophil degranulation+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0015991///ATP hydrolysis coupled proton transport","T cell immune regulator 1, ATPase H+ transporting V0 subunit a3","[VPP3_HUMAN|Reviewed]RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 3; Short=V-ATPase 116 kDa isoform a3; AltName: Full=Osteoclastic proton pump 116 kDa subunit; Short=OC-116 kDa; Short=OC116; AltName: Full=T-cell immune regulator 1; AltName: Full=T-cell immune response cDNA7 protein; Short=TIRC7; AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3;+++[A0A024R5E5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PM12_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[E9PMC5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PNA6_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YCE3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YEL3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q64F87_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN4_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 8 {ECO:0000313|EMBL:AAS59838.1}; Flags: Fragment;+++[Q6QBN5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN6_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 6 {ECO:0000313|EMBL:AAS59836.1}; Flags: Fragment;+++[Q6QBN7_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN8_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q8TCH1_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;"]
[10313,"'RTN3'",2250,1995,2047,2097.33333333333,"05010///Alzheimer's disease",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0071786///endoplasmic reticulum tubular network organization+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:0016032///viral process+++GO:0016192///vesicle-mediated transport+++GO:0006915///apoptotic process","reticulon 3","[RTN3_HUMAN|Reviewed]RecName: Full=Reticulon-3; AltName: Full=Homolog of ASY protein; Short=HAP; AltName: Full=Neuroendocrine-specific protein-like 2; Short=NSP-like protein 2; AltName: Full=Neuroendocrine-specific protein-like II; Short=NSP-like protein II; Short=NSPLII;+++[A0A024R5C4_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[B7Z4M1_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[F5GWG7_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000441614}; Flags: Fragment;+++[F5H617_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[F5H891_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000442080}; Flags: Fragment;+++[Q7RTN4_HUMAN|Unreviewed]SubName: Full=Truncated RTN3-A3 {ECO:0000313|EMBL:DAA01930.1};"]
[10314,"'LANCL1'",406,334,401,380.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0017124///SH3 domain binding+++GO:0008270///zinc ion binding+++GO:0043295///glutathione binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway","LanC like 1","[LANC1_HUMAN|Reviewed]RecName: Full=LanC-like protein 1; AltName: Full=40 kDa erythrocyte membrane protein; Short=p40;+++[A0A024R3Z5_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_b {ECO:0000313|EMBL:EAW70491.1};+++[B2R602_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92709, highly similar to Homo sapiens LanC lantibiotic synthetase component C-like 1 (bacterial) (LANCL1), mRNA {ECO:0000313|EMBL:BAG35299.1};+++[E9PHS0_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000396518}; Flags: Fragment;+++[F8WDS9_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000395442};+++[H7C2E3_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000405364}; Flags: Fragment;+++[Q53TN2_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_a {ECO:0000313|EMBL:EAW70487.1};+++[Q6FHH6_HUMAN|Unreviewed]SubName: Full=LANCL1 protein {ECO:0000313|EMBL:CAG46576.1}; Flags: Fragment;"]
[10316,"'NMUR1'",5,9,9,7.66666666666667,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0001607///neuromedin U receptor activity+++GO:0042924///neuromedin U binding","GO:0007202///activation of phospholipase C activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006816///calcium ion transport+++GO:0007165///signal transduction+++GO:0048016///inositol phosphate-mediated signaling+++GO:0006939///smooth muscle contraction+++GO:0019722///calcium-mediated signaling+++GO:0007218///neuropeptide signaling pathway+++GO:0006821///chloride transport","neuromedin U receptor 1","[NMUR1_HUMAN|Reviewed]RecName: Full=Neuromedin-U receptor 1; Short=NMU-R1; AltName: Full=G-protein coupled receptor 66; AltName: Full=G-protein coupled receptor FM-3;+++[L8E9D8_HUMAN|Unreviewed]SubName: Full=Alternative protein NMUR1 {ECO:0000313|EMBL:CCQ43346.1};"]
[10317,"'B3GALT5'",9,23,18,16.6666666666667,"01100///Metabolic pathways+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,"M00070///Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer","R05964///UDP-D-galactose + Globoside <=> UDP + Galactosylgloboside+++R06006///UDP-D-galactose + Lc3Cer <=> UDP + Lc4Cer","GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity","GO:0009312///oligosaccharide biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006486///protein glycosylation+++GO:0009617///response to bacterium","beta-1,3-galactosyltransferase 5","[B3GT5_HUMAN|Reviewed]RecName: Full=Beta-1,3-galactosyltransferase 5; Short=Beta-1,3-GalTase 5; Short=Beta3Gal-T5; Short=Beta3GalT5; Short=b3Gal-T5; EC=2.4.1.-; AltName: Full=Beta-3-Gx-T5; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5;+++[A0A0A0MS93_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};"]
[10318,"'TNIP1'",3157.12,3361.01,3108,3208.71,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0070034///telomerase RNA binding+++GO:0005515///protein binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0003723///RNA binding","GO:0043489///RNA stabilization+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0051973///positive regulation of telomerase activity+++GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0050727///regulation of inflammatory response+++GO:0006364///rRNA processing+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:0042254///ribosome biogenesis+++GO:0045071///negative regulation of viral genome replication+++GO:0006954///inflammatory response+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000493///box H/ACA snoRNP assembly+++GO:0001522///pseudouridine synthesis+++GO:0009101///glycoprotein biosynthetic process+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007159///leukocyte cell-cell adhesion+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0085032///modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade+++GO:0006952///defense response+++GO:1905323///telomerase holoenzyme complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090669///telomerase RNA stabilization+++GO:0050729///positive regulation of inflammatory response+++GO:0006412///translation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016579///protein deubiquitination","TNFAIP3 interacting protein 1","[TNIP1_HUMAN|Reviewed]RecName: Full=TNFAIP3-interacting protein 1; AltName: Full=A20-binding inhibitor of NF-kappa-B activation 1; Short=ABIN-1; AltName: Full=HIV-1 Nef-interacting protein; AltName: Full=Nef-associated factor 1; Short=Naf1; AltName: Full=Nip40-1; AltName: Full=Virion-associated nuclear shuttling protein; Short=VAN; Short=hVAN;+++[A0A0A0MRZ4_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000374029};+++[A8K4N4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77844, highly similar to Homo sapiens TNFAIP3 interacting protein 1, mRNA {ECO:0000313|EMBL:BAF83688.1};+++[B7Z8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61022, highly similar to Nef-associated factor 1 {ECO:0000313|EMBL:BAH13988.1};+++[E7EMV7_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427854};+++[E7EW15_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428487}; Flags: Fragment;+++[E7EW68_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430279}; Flags: Fragment;+++[E7EWG2_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428404}; Flags: Fragment;+++[H0YC17_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430739}; Flags: Fragment;"]
[10319,"'LAMC3'",5,4,9,6,"05146///Amoebiasis+++04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05145///Toxoplasmosis+++05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04510///Focal adhesion",{"$nulls":3},"GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005604///basement membrane","GO:0005198///structural molecule activity","GO:0030198///extracellular matrix organization+++GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0060041///retina development in camera-type eye+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0014002///astrocyte development","laminin subunit gamma 3","[LAMC3_HUMAN|Reviewed]RecName: Full=Laminin subunit gamma-3; AltName: Full=Laminin-12 subunit gamma; AltName: Full=Laminin-14 subunit gamma; AltName: Full=Laminin-15 subunit gamma; Flags: Precursor;+++[H7BY04_HUMAN|Unreviewed]SubName: Full=Laminin subunit gamma-3 {ECO:0000313|Ensembl:ENSP00000347627}; Flags: Fragment;+++[Q8N2D6_HUMAN|Unreviewed]SubName: Full=cDNA PSEC0236 fis, clone HEMBA1007104, highly similar to Laminin gamma-3 chain {ECO:0000313|EMBL:BAC11679.1};"]
[1032,"'CDKN2D'",42,30,31,34.3333333333333,"04068///FoxO signaling pathway+++04110///Cell cycle",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0097129///cyclin D2-CDK4 complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding","GO:0009411///response to UV+++GO:0033280///response to vitamin D+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0007605///sensory perception of sound+++GO:0042326///negative regulation of phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0007050///cell cycle arrest+++GO:0032526///response to retinoic acid+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:0007049///cell cycle+++GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","cyclin dependent kinase inhibitor 2D","[CDN2D_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor D; AltName: Full=p19-INK4d;+++[A0A024R796_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2D (P19, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAW84123.1};"]
[10320,"'IKZF1'",19,32,38,29.6666666666667,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0031618///nuclear pericentric heterochromatin+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding","GO:0030098///lymphocyte differentiation+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0051291///protein heterooligomerization+++GO:0006325///chromatin organization+++GO:0030218///erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007498///mesoderm development","IKAROS family zinc finger 1","[IKZF1_HUMAN|Reviewed]RecName: Full=DNA-binding protein Ikaros; AltName: Full=Ikaros family zinc finger protein 1; AltName: Full=Lymphoid transcription factor LyF-1;+++[A0A087WU46_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000478368};+++[A0A0A0MRA0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000340080};+++[A0A0A0MST1_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000401507};+++[A0A2R8Y4D3_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000493696};+++[A0A2R8Y4T7_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000494055}; Flags: Fragment;+++[A0A2R8YFR0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000496655}; Flags: Fragment;+++[C9JTB0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000388478};+++[Q3T907_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000409588}; SubName: Full=Zinc finger protein, subfamily 1A, 1 (Ikaros) {ECO:0000313|EMBL:CAJ29975.1}; Flags: Fragment;+++[Q9P1M1_HUMAN|Unreviewed]SubName: Full=PRO0758 {ECO:0000313|EMBL:AAF71030.1}; SubName: Full=Zinc finger protein, subfamily 1A, 1 (Ikaros), isoform CRA_c {ECO:0000313|EMBL:EAW60980.1};+++[R9R4D9_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000483016}; SubName: Full=IKAROS family zinc finger 1 isoform 14 {ECO:0000313|EMBL:AGI59420.1};"]
[10322,"'SMYD5'",540,500,466.45,502.15,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0032259///methylation+++GO:0008150///biological_process","SMYD family member 5","[SMYD5_HUMAN|Reviewed]RecName: Full=SET and MYND domain-containing protein 5; EC=2.1.1.-; AltName: Full=Protein NN8-4AG; AltName: Full=Retinoic acid-induced protein 15;+++[C9IYN9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000412587}; Flags: Fragment;+++[E2QRN5_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000258100};+++[F8WEJ9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000388195};"]
[10324,"'KLHL41'",76,51,43,56.6666666666667,null,"H00698///Nemaline myopathy",null,null,"GO:0016529///sarcoplasmic reticulum+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031143///pseudopodium+++GO:0001726///ruffle+++GO:0031430///M band+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0035914///skeletal muscle cell differentiation+++GO:2000291///regulation of myoblast proliferation+++GO:0048741///skeletal muscle fiber development+++GO:0006941///striated muscle contraction+++GO:0030239///myofibril assembly+++GO:0045214///sarcomere organization+++GO:0043687///post-translational protein modification+++GO:0031275///regulation of lateral pseudopodium assembly+++GO:0045661///regulation of myoblast differentiation+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0016567///protein ubiquitination","kelch like family member 41","[KLH41_HUMAN|Reviewed]RecName: Full=Kelch-like protein 41; AltName: Full=Kel-like protein 23; AltName: Full=Kelch repeat and BTB domain-containing protein 10; AltName: Full=Kelch-related protein 1; AltName: Full=Sarcosin;+++[Q3ZTS6_HUMAN|Unreviewed]SubName: Full=Sarcomeric muscle protein {ECO:0000313|EMBL:AAQ76811.1}; Flags: Fragment;"]
[10325,"'RRAGB'",259,246.99,268,257.996666666667,"04140///Autophagy - animal+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0034448///EGO complex+++GO:1990131///Gtr1-Gtr2 GTPase complex+++GO:0005765///lysosomal membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0051020///GTPase binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0032561///guanyl ribonucleotide binding","GO:1904263///positive regulation of TORC1 signaling+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0007050///cell cycle arrest+++GO:0034198///cellular response to amino acid starvation+++GO:0009267///cellular response to starvation+++GO:0034613///cellular protein localization+++GO:0010506///regulation of autophagy+++GO:0032006///regulation of TOR signaling+++GO:1990253///cellular response to leucine starvation","Ras related GTP binding B","[RRAGB_HUMAN|Reviewed]RecName: Full=Ras-related GTP-binding protein B {ECO:0000305}; Short=Rag B {ECO:0000303|PubMed:11073942}; Short=RagB {ECO:0000303|PubMed:7499430};+++[Q5VZM0_HUMAN|Unreviewed]SubName: Full=Ras-related GTP-binding protein B {ECO:0000313|Ensembl:ENSP00000410630}; Flags: Fragment;"]
[10327,"'AKR1A1'",883,864,916,887.666666666667,"01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++00040///Pentose and glucuronate interconversions+++00561///Glycerolipid metabolism+++00930///Caprolactam degradation+++01130///Biosynthesis of antibiotics+++01220///Degradation of aromatic compounds+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis",null,"M00014///Glucuronate pathway (uronate pathway)","R01041///glycerol:NADP+ oxidoreductase   Glycerol + NADP+ <=> D-Glyceraldehyde + NADPH + H++++R05231///6-Hydroxyhexanoate:NADP+ oxidoreductase   6-Hydroxyhexanoic acid + NADP+ <=> Adipate semialdehyde + NADPH + H++++R00746///Ethanol:NADP+ oxidoreductase   Ethanol + NADP+ <=> Acetaldehyde + NADPH + H++++R01481///L-gulonate:NADP+ 6-oxidoreductase   L-Gulonate + NADP+ <=> D-Glucuronate + NADPH + H+","GO:0045202///synapse+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0009055///electron transfer activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0047939///L-glucuronate reductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0005515///protein binding+++GO:0016972///thiol oxidase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0016491///oxidoreductase activity","GO:0042840///D-glucuronate catabolic process+++GO:0022900///electron transport chain+++GO:0006081///cellular aldehyde metabolic process+++GO:0019853///L-ascorbic acid biosynthetic process+++GO:1901687///glutathione derivative biosynthetic process+++GO:0006006///glucose metabolic process+++GO:0055114///oxidation-reduction process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0046185///aldehyde catabolic process","aldo-keto reductase family 1 member A1","[AK1A1_HUMAN|Reviewed]RecName: Full=Alcohol dehydrogenase [NADP(+)]; EC=1.1.1.2; AltName: Full=Aldehyde reductase; AltName: Full=Aldo-keto reductase family 1 member A1;+++[Q5T621_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000398414}; Flags: Fragment;+++[Q9H2X5_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[Q9NY86_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[V9GYG2_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476713};+++[V9GYP9_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476978}; Flags: Fragment;+++[V9HWI0_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 6 {ECO:0000313|EMBL:ACF94472.1}; SubName: Full=Epididymis secretory sperm binding protein Li 165mP {ECO:0000313|EMBL:ACJ13642.1};"]
[10328,"'EMC8'",321,322,283,308.666666666667,"00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01100///Metabolic pathways+++05016///Huntington's disease+++04714///Thermogenesis+++04260///Cardiac muscle contraction+++05012///Parkinson's disease","H00920///Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis","M00154///Cytochrome c oxidase",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0072546///ER membrane protein complex","GO:0005515///protein binding",null,"ER membrane protein complex subunit 8","[EMC8_HUMAN|Reviewed]RecName: Full=ER membrane protein complex subunit 8; AltName: Full=Neighbor of COX4; AltName: Full=Protein FAM158B;+++[M0R1B0_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 8 {ECO:0000313|Ensembl:ENSP00000471751}; Flags: Fragment;+++[Q53Y03_HUMAN|Unreviewed]SubName: Full=COX4 neighbor, isoform CRA_a {ECO:0000313|EMBL:EAW95439.1}; SubName: Full=Neighbor of COX4 {ECO:0000313|EMBL:AAP35796.1}; SubName: Full=cDNA, FLJ94626, Homo sapiens neighbor of COX4 (NOC4), mRNA {ECO:0000313|EMBL:BAG36691.1};"]
[10329,"'RXYLT1'",260,215,258,244.333333333333,"00515///Mannose type O-glycan biosynthesis+++01100///Metabolic pathways","H00120///Muscular dystrophy-dystroglycanopathy type A",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane","GO:0016740///transferase activity+++GO:0120053///ribitol beta-1,4-xylosyltransferase activity","GO:0035269///protein O-linked mannosylation+++GO:0006486///protein glycosylation","ribitol xylosyltransferase 1","[RXLT1_HUMAN|Reviewed]RecName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000305}; EC=2.4.2.- {ECO:0000269|PubMed:27733679}; AltName: Full=Transmembrane protein 5 {ECO:0000305}; AltName: Full=UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase {ECO:0000303|PubMed:27733679};+++[F5GXF8_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440845};+++[G3V1K2_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440280}; SubName: Full=Transmembrane protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW97120.1};"]
[1033,"'CDKN3'",64,56,46,55.3333333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity","GO:0006470///protein dephosphorylation+++GO:0007050///cell cycle arrest+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0007049///cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle","cyclin dependent kinase inhibitor 3","[CDKN3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=CDK2-associated dual-specificity phosphatase; AltName: Full=Cyclin-dependent kinase interactor 1; AltName: Full=Cyclin-dependent kinase-interacting protein 2; AltName: Full=Kinase-associated phosphatase;+++[A0A087WW25_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000479875};+++[A0A087WWK3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[A0A0S2KP18_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 splice variant {ECO:0000313|EMBL:ALO50058.1};+++[F5H232_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000445572};+++[F8WD24_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000378944};+++[G3V1K6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000440404};+++[G3V2J7_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[H7C0S3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};"]
[10330,"'CNPY2'",2101,2062,1907,2023.33333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:0010629///negative regulation of gene expression+++GO:0045716///positive regulation of low-density lipoprotein particle receptor biosynthetic process","canopy FGF signaling regulator 2","[CNPY2_HUMAN|Reviewed]RecName: Full=Protein canopy homolog 2; AltName: Full=MIR-interacting saposin-like protein; AltName: Full=Putative secreted protein Zsig9; AltName: Full=Transmembrane protein 4; Flags: Precursor;+++[F8VXJ7_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448809}; Flags: Fragment;+++[F8W1K5_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000446784}; Flags: Fragment;+++[H0YI18_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448333}; Flags: Fragment;+++[H0YIH9_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000449444}; Flags: Fragment;"]
[10333,"'TLR6'",6,4.65,9,6.55,"04620///Toll-like receptor signaling pathway+++05152///Tuberculosis+++05142///Chagas disease (American trypanosomiasis)+++04145///Phagosome",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0035355///Toll-like receptor 2-Toll-like receptor 6 protein complex+++GO:0045121///membrane raft+++GO:0030670///phagocytic vesicle membrane+++GO:0005794///Golgi apparatus","GO:0035663///Toll-like receptor 2 binding+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0071723///lipopeptide binding+++GO:0038023///signaling receptor activity+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0038124///toll-like receptor TLR6:TLR2 signaling pathway+++GO:0002376///immune system process+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0032493///response to bacterial lipoprotein+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:0046209///nitric oxide metabolic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043032///positive regulation of macrophage activation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045410///positive regulation of interleukin-6 biosynthetic process+++GO:2000483///negative regulation of interleukin-8 secretion+++GO:0045087///innate immune response+++GO:0002224///toll-like receptor signaling pathway+++GO:0001775///cell activation+++GO:0042742///defense response to bacterium+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:1904646///cellular response to amyloid-beta+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0034150///toll-like receptor 6 signaling pathway+++GO:0006954///inflammatory response+++GO:0042496///detection of diacyl bacterial lipopeptide+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0010628///positive regulation of gene expression+++GO:0001774///microglial cell activation+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0050707///regulation of cytokine secretion+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:0050702///interleukin-1 beta secretion+++GO:0071726///cellular response to diacyl bacterial lipopeptide","toll like receptor 6","[TLR6_HUMAN|Reviewed]RecName: Full=Toll-like receptor 6; AltName: CD_antigen=CD286; Flags: Precursor;+++[B2R933_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH37_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH42_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH44_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH45_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6RFS7_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS91_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS92_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS93_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS96_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS97_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS98_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS99_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CSA0_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D6R979_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000423326}; Flags: Fragment;+++[D6RAV7_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000424718}; Flags: Fragment;"]
[103344718,"'HOTS'",0,0,1,0.333333333333333,{"$nulls":7},"H19 opposite tumor suppressor","[A0A2J8JV55_PANTR|diamond]SubName: Full=H19 isoform 2 {ECO:0000313|EMBL:PNI26653.1};+++[A0A2J8JVA8_PANTR|diamond]SubName: Full=H19 isoform 3 {ECO:0000313|EMBL:PNI26654.1};+++[A0A2J8S6L6_PONAB|diamond]SubName: Full=H19 isoform 14 {ECO:0000313|EMBL:PNJ16425.1};+++[A0A2J8S6P3_PONAB|diamond]SubName: Full=H19 isoform 13 {ECO:0000313|EMBL:PNJ16424.1};+++[Q9P1C7_HUMAN|diamond]SubName: Full=PRO2605 {ECO:0000313|EMBL:AAF71129.1};"]
[10335,"'MRVI1'",86,37,41,54.6666666666667,"04270///Vascular smooth muscle contraction+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031095///platelet dense tubular network membrane","GO:0005515///protein binding",null,"murine retrovirus integration site 1 homolog","[MRVI1_HUMAN|Reviewed]RecName: Full=Protein MRVI1; AltName: Full=Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; AltName: Full=JAW1-related protein MRVI1;+++[E9PJ61_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000435658};+++[E9PNK7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000434741};+++[E9PRG4_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432325}; Flags: Fragment;+++[E9PRH0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432312};+++[H0YCL0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000431845}; Flags: Fragment;+++[H0YDM7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000433970}; Flags: Fragment;+++[H0YI08_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432067};"]
[10336,"'PCGF3'",678,698,625,667,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0035102///PRC1 complex+++GO:0005634///nucleus+++GO:0031519///PcG protein complex+++GO:0000805///X chromosome+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding","GO:0060819///inactivation of X chromosome by genetic imprinting+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036353///histone H2A-K119 monoubiquitination","polycomb group ring finger 3","[PCGF3_HUMAN|Reviewed]RecName: Full=Polycomb group RING finger protein 3; AltName: Full=RING finger protein 3A;+++[A0A087WVH5_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000479441};+++[B3KQ06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32562 fis, clone SPLEN1000165, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG51868.1};+++[B3KWT8_HUMAN|Unreviewed]SubName: Full=Polycomb group ring finger 3, isoform CRA_b {ECO:0000313|EMBL:EAW82654.1}; SubName: Full=cDNA FLJ43813 fis, clone TESTI4001467, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG54250.1};+++[B4DTN5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54810, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG62047.1};+++[B5MEC4_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000383015};+++[C9J3G7_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000398493}; Flags: Fragment;+++[C9JGV3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000416279}; Flags: Fragment;+++[C9JYD0_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000401431}; Flags: Fragment;+++[F2Z3P3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000405840};"]
[10342,"'TFG'",2929,3064,3170,3054.33333333333,"05200///Pathways in cancer+++05216///Thyroid cancer","H00266///Hereditary spastic paraplegia (SPG)+++H00032///Thyroid cancer",null,null,"GO:0070971///endoplasmic reticulum exit site+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport","TRK-fused gene","[TFG_HUMAN|Reviewed]RecName: Full=Protein TFG; AltName: Full=TRK-fused gene protein;+++[C9JJP5_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000420797}; Flags: Fragment;+++[C9JTY3_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419559}; Flags: Fragment;+++[C9JUE0_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419504}; Flags: Fragment;+++[Q05BK6_HUMAN|Unreviewed]SubName: Full=TFG protein {ECO:0000313|EMBL:AAH41600.1};"]
[10343,"'PKDREJ'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding","GO:0006811///ion transport+++GO:0050982///detection of mechanical stimulus+++GO:0007340///acrosome reaction+++GO:0070588///calcium ion transmembrane transport","polycystin family receptor for egg jelly","[PKDRE_HUMAN|Reviewed]RecName: Full=Polycystic kidney disease and receptor for egg jelly-related protein; AltName: Full=PKD and REJ homolog; Flags: Precursor;"]
[10344,"'CCL26'",5,1,2,2.66666666666667,"04062///Chemokine signaling pathway+++04060///Cytokine-cytokine receptor interaction","H01361///Eosinophilic esophagitis+++H01360///Allergic rhinitis",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008009///chemokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity+++GO:0048020///CCR chemokine receptor binding+++GO:0005125///cytokine activity+++GO:0031728///CCR3 chemokine receptor binding","GO:0043547///positive regulation of GTPase activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0048245///eosinophil chemotaxis+++GO:0006955///immune response+++GO:0071347///cellular response to interleukin-1+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0006954///inflammatory response+++GO:0048247///lymphocyte chemotaxis+++GO:0007267///cell-cell signaling+++GO:0070098///chemokine-mediated signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0050921///positive regulation of chemotaxis+++GO:0006935///chemotaxis+++GO:0071346///cellular response to interferon-gamma+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0010818///T cell chemotaxis+++GO:0002548///monocyte chemotaxis","C-C motif chemokine ligand 26","[CCL26_HUMAN|Reviewed]RecName: Full=C-C motif chemokine 26; AltName: Full=CC chemokine IMAC; AltName: Full=Eotaxin-3; AltName: Full=Macrophage inflammatory protein 4-alpha; Short=MIP-4-alpha; AltName: Full=Small-inducible cytokine A26; AltName: Full=Thymic stroma chemokine-1; Short=TSC-1; Flags: Precursor;"]
[10345,"'TRDN'",37,60,30,42.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0030314///junctional membrane complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0030674///protein binding, bridging","GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0090158///endoplasmic reticulum membrane organization+++GO:0006936///muscle contraction+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0010649///regulation of cell communication by electrical coupling+++GO:1903779///regulation of cardiac conduction+++GO:0060047///heart contraction+++GO:0009617///response to bacterium+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0031122///cytoplasmic microtubule organization+++GO:1901846///positive regulation of cell communication by electrical coupling involved in cardiac conduction","triadin","[TRDN_HUMAN|Reviewed]RecName: Full=Triadin;+++[H0Y6P0_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000406768}; Flags: Fragment;+++[H7BY47_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000354307}; Flags: Fragment;+++[H9ME53_HUMAN|Unreviewed]SubName: Full=Cardiac triadin Trisk 32 isoform {ECO:0000313|EMBL:AEW10557.1}; SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000439281};+++[Q05C44_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH29393.1}; Flags: Fragment;+++[Q6PG49_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH57222.1}; Flags: Fragment;+++[Q8IVK2_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|EMBL:CAD33526.2};"]
[10346,"'TRIM22'",1155,947,989,1030.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0016740///transferase activity+++GO:0003714///transcription corepressor activity+++GO:0030674///protein binding, bridging+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0016032///viral process+++GO:0010508///positive regulation of autophagy+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0016567///protein ubiquitination+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0009615///response to virus+++GO:0032880///regulation of protein localization+++GO:0051607///defense response to virus+++GO:0070206///protein trimerization+++GO:0006955///immune response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity","tripartite motif containing 22","[TRI22_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM22; EC=2.3.2.27; AltName: Full=50 kDa-stimulated trans-acting factor; AltName: Full=RING finger protein 94; AltName: Full=RING-type E3 ubiquitin transferase TRIM22 {ECO:0000305}; AltName: Full=Staf-50; AltName: Full=Tripartite motif-containing protein 22;+++[B4DQS5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51049, highly similar to Tripartite motif-containing protein 22 {ECO:0000313|EMBL:BAG61037.1};+++[C9J060_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000400417}; Flags: Fragment;+++[C9JIU5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000396849}; Flags: Fragment;+++[C9JWC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000393250}; Flags: Fragment;+++[D3DQT0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_b {ECO:0000313|EMBL:EAW68770.1};+++[D3DQT1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_a {ECO:0000313|EMBL:EAW68768.1};+++[H7BZD3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000388994}; Flags: Fragment;+++[H7C262_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000404204}; Flags: Fragment;+++[H7C2K0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000406412}; Flags: Fragment;+++[H7C376_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000409991}; Flags: Fragment;+++[Q4A1P5_HUMAN|Unreviewed]SubName: Full=Tripartite binding motif 22 {ECO:0000313|EMBL:CAJ13842.1}; Flags: Fragment;"]
[10347,"'ABCA7'",1203,1646,1459,1436,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0001891///phagocytic cup+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0090556///phosphatidylserine-translocating ATPase activity+++GO:0034188///apolipoprotein A-I receptor activity+++GO:0005515///protein binding+++GO:0005319///lipid transporter activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:1902430///negative regulation of amyloid-beta formation+++GO:0033700///phospholipid efflux+++GO:0033344///cholesterol efflux+++GO:0050766///positive regulation of phagocytosis+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0018149///peptide cross-linking+++GO:0055085///transmembrane transport+++GO:0010875///positive regulation of cholesterol efflux+++GO:1902995///positive regulation of phospholipid efflux+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034504///protein localization to nucleus+++GO:0006909///phagocytosis+++GO:0007613///memory+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901076///positive regulation of engulfment of apoptotic cell+++GO:0045332///phospholipid translocation+++GO:0006869///lipid transport","ATP binding cassette subfamily A member 7","[ABCA7_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 7; AltName: Full=ABCA-SSN; AltName: Full=Autoantigen SS-N; AltName: Full=Macrophage ABC transporter;+++[A0A087WUR5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000478857}; Flags: Fragment;+++[A0A087WX86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000480811}; Flags: Fragment;+++[A0A087WZX6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000482948}; Flags: Fragment;+++[B3KUJ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40025 fis, clone STOMA2008050, highly similar to Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 7 (ABCA7), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53455.1};+++[D6W5Y0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family A (ABC1), member 7, isoform CRA_e {ECO:0000313|EMBL:EAW69563.1};+++[E9PKG5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000433545}; Flags: Fragment;+++[E9PL63_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000431473}; Flags: Fragment;+++[H0YCN5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000432031}; Flags: Fragment;+++[H0YF58_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000437311}; Flags: Fragment;+++[L8EB07_HUMAN|Unreviewed]SubName: Full=Alternative protein ABCA7 {ECO:0000313|EMBL:CCQ43618.1};"]
[10349,"'ABCA10'",24,25,19,22.6666666666667,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005319///lipid transporter activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0006869///lipid transport+++GO:0055085///transmembrane transport","ATP binding cassette subfamily A member 10","[ABCAA_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 10;+++[E5RFN6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000428032};+++[E5RFP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000430341};+++[H0YBL8_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000429795}; Flags: Fragment;+++[K7EMH5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000466506}; Flags: Fragment;+++[K7ERP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000468351}; Flags: Fragment;"]
[10350,"'ABCA9'",5,5.99,6,5.66333333333333,"02010///ABC transporters",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005319///lipid transporter activity","GO:0055085///transmembrane transport+++GO:0006869///lipid transport","ATP binding cassette subfamily A member 9","[ABCA9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 9;+++[H0Y4U7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000394264};+++[K7EJJ0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000465191}; Flags: Fragment;"]
[10351,"'ABCA8'",0,1,3,1.33333333333333,"02010///ABC transporters",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0000166///nucleotide binding+++GO:0008559///xenobiotic transmembrane transporting ATPase activity+++GO:0005524///ATP binding+++GO:0005319///lipid transporter activity","GO:0006869///lipid transport+++GO:0006855///drug transmembrane transport+++GO:0042908///xenobiotic transport+++GO:0055085///transmembrane transport","ATP binding cassette subfamily A member 8","[ABCA8_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 8;+++[A0A024R8L6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family A (ABC1), member 8, isoform CRA_a {ECO:0000313|EMBL:EAW89069.1};+++[A0A075B774_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 8 {ECO:0000313|Ensembl:ENSP00000467186}; Flags: Fragment;+++[A0A0A0MSU4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 8 {ECO:0000313|Ensembl:ENSP00000402814};+++[K7ELK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 8 {ECO:0000313|Ensembl:ENSP00000466126}; Flags: Fragment;+++[Q49AI9_HUMAN|Unreviewed]SubName: Full=ABCA8 protein {ECO:0000313|EMBL:AAH37309.1}; SubName: Full=ATP-binding cassette sub-family A member 8 {ECO:0000313|Ensembl:ENSP00000481467};"]
[10352,"'WARS2'",181,190,173,181.333333333333,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03664///L-Tryptophan -tRNA(Trp) ligase (AMP-forming)   ATP + L-Tryptophan + tRNA(Trp) <=> AMP + Diphosphate + L-Tryptophanyl-tRNA(Trp)","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000166///nucleotide binding+++GO:0004830///tryptophan-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding","GO:0006436///tryptophanyl-tRNA aminoacylation+++GO:0001570///vasculogenesis+++GO:0006412///translation+++GO:0070183///mitochondrial tryptophanyl-tRNA aminoacylation+++GO:0006418///tRNA aminoacylation for protein translation","tryptophanyl tRNA synthetase 2, mitochondrial","[SYWM_HUMAN|Reviewed]RecName: Full=Tryptophan--tRNA ligase, mitochondrial; EC=6.1.1.2; AltName: Full=(Mt)TrpRS; AltName: Full=Tryptophanyl-tRNA synthetase; Short=TrpRS; Flags: Precursor;+++[B7Z448_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51886, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH12434.1};+++[B7Z6G7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53098, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH13253.1};"]
[1036,"'CDO1'",1053,1311,1310,1224.66666666667,"00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00430///Taurine and hypotaurine metabolism",null,null,"R00893///L-Cysteine:oxygen oxidoreductase   L-Cysteine + Oxygen <=> 3-Sulfino-L-alanine","GO:0005829///cytosol","GO:0005506///iron ion binding+++GO:0017172///cysteine dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0008198///ferrous iron binding+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","GO:0010243///response to organonitrogen compound+++GO:0045471///response to ethanol+++GO:0051384///response to glucocorticoid+++GO:0019448///L-cysteine catabolic process+++GO:0043200///response to amino acid+++GO:0007595///lactation+++GO:0055114///oxidation-reduction process+++GO:0051591///response to cAMP+++GO:0000097///sulfur amino acid biosynthetic process+++GO:0006954///inflammatory response+++GO:0006534///cysteine metabolic process+++GO:0042412///taurine biosynthetic process+++GO:0033762///response to glucagon","cysteine dioxygenase type 1","[CDO1_HUMAN|Reviewed]RecName: Full=Cysteine dioxygenase type 1; EC=1.13.11.20; AltName: Full=Cysteine dioxygenase type I; Short=CDO; Short=CDO-I;"]
[10360,"'NPM3'",202,255,211,222.666666666667,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0038023///signaling receptor activity","GO:0009303///rRNA transcription+++GO:0070267///oncosis+++GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing","nucleophosmin/nucleoplasmin 3","[NPM3_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-3;"]
[10361,"'NPM2'",2,3,2,2.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0000789///cytoplasmic chromatin+++GO:0000790///nuclear chromatin+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0042393///histone binding","GO:0007338///single fertilization+++GO:0009994///oocyte differentiation+++GO:0006325///chromatin organization+++GO:0051260///protein homooligomerization+++GO:0045740///positive regulation of DNA replication+++GO:0043085///positive regulation of catalytic activity+++GO:0001824///blastocyst development+++GO:0006338///chromatin remodeling+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0051054///positive regulation of DNA metabolic process+++GO:0007275///multicellular organism development+++GO:0007096///regulation of exit from mitosis","nucleophosmin/nucleoplasmin 2","[NPM2_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-2;+++[E5RFQ8_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000428016}; Flags: Fragment;+++[E5RGN1_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000429984}; Flags: Fragment;"]
[10362,"'HMG20B'",1769,1718,1743,1743.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016604///nuclear body+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004407///histone deacetylase activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0035914///skeletal muscle cell differentiation+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007596///blood coagulation+++GO:0033234///negative regulation of protein sumoylation+++GO:0045666///positive regulation of neuron differentiation","high mobility group 20B","[HM20B_HUMAN|Reviewed]RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; Short=SMARCE1-related protein; AltName: Full=BRCA2-associated factor 35; AltName: Full=HMG box-containing protein 20B; AltName: Full=HMG domain-containing protein 2; AltName: Full=HMG domain-containing protein HMGX2; AltName: Full=Sox-like transcriptional factor; AltName: Full=Structural DNA-binding protein BRAF35;+++[A4IF61_HUMAN|Unreviewed]SubName: Full=HMG20B protein {ECO:0000313|EMBL:AAI34414.1}; Flags: Fragment;+++[B5MDG7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000262949}; Flags: Fragment;+++[C9J8X5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000410924}; Flags: Fragment;+++[C9JQA7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000402877}; Flags: Fragment;+++[C9K049_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393904}; Flags: Fragment;+++[F8WES5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393481};+++[K7EJR8_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000465293}; Flags: Fragment;+++[Q8WYT5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein pp8857 {ECO:0000313|EMBL:AAL55873.1};"]
[10363,"'HMG20A'",811,748,668,742.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:0033234///negative regulation of protein sumoylation+++GO:0045665///negative regulation of neuron differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006325///chromatin organization","high mobility group 20A","[HM20A_HUMAN|Reviewed]RecName: Full=High mobility group protein 20A; AltName: Full=HMG box-containing protein 20A; AltName: Full=HMG domain-containing protein 1; AltName: Full=HMG domain-containing protein HMGX1;+++[B4DMG1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57155, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAG59873.1}; SubName: Full=cDNA, FLJ79180, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAH14652.1};+++[H0YK55_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452665}; Flags: Fragment;+++[H0YKL0_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452847}; Flags: Fragment;+++[H0YKM5_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452864}; Flags: Fragment;+++[H0YM80_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453498}; Flags: Fragment;+++[H0YMG2_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453592};+++[H0YMS9_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453727}; Flags: Fragment;+++[H0YNS8_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000454136}; Flags: Fragment;"]
[10365,"'KLF2'",22,17,27,22,"05418///Fluid shear stress and atherosclerosis+++04371///Apelin signaling pathway+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0001701///in utero embryonic development+++GO:0070301///cellular response to hydrogen peroxide+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:0043249///erythrocyte maturation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060509///type I pneumocyte differentiation+++GO:0071498///cellular response to fluid shear stress+++GO:0035264///multicellular organism growth+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071409///cellular response to cycloheximide+++GO:0032715///negative regulation of interleukin-6 production+++GO:0000902///cell morphogenesis+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0034616///response to laminar fluid shear stress+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0040029///regulation of gene expression, epigenetic+++GO:1901653///cellular response to peptide+++GO:0071347///cellular response to interleukin-1+++GO:0051247///positive regulation of protein metabolic process+++GO:0034101///erythrocyte homeostasis+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0097533///cellular stress response to acid chemical+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0000122///negative regulation of transcription by RNA polymerase II","Kruppel like factor 2","[KLF2_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 2; AltName: Full=Lung krueppel-like factor;+++[K7EJ60_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 2 {ECO:0000313|Ensembl:ENSP00000465035};"]
[10367,"'MICU1'",1076,1138,1037,1083.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0032592///integral component of mitochondrial membrane+++GO:0034704///calcium channel complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005622///intracellular+++GO:1990246///uniplex complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0042802///identical protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0070509///calcium ion import+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051260///protein homooligomerization+++GO:0006952///defense response+++GO:0036444///calcium import into the mitochondrion+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0006851///mitochondrial calcium ion transmembrane transport","mitochondrial calcium uptake 1","[MICU1_HUMAN|Reviewed]RecName: Full=Calcium uptake protein 1, mitochondrial; AltName: Full=Atopy-related autoantigen CALC {ECO:0000303|PubMed:16002733}; Short=ara CALC {ECO:0000303|PubMed:16002733}; AltName: Full=Calcium-binding atopy-related autoantigen 1 {ECO:0000303|PubMed:16002733}; AltName: Allergen=Hom s 4 {ECO:0000303|PubMed:16002733}; Flags: Precursor;+++[A0A0U1RRK1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000489563};+++[A0A286YF11_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000493232};+++[E9PQV6_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000432492}; Flags: Fragment;+++[F6XEV2_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000381745};+++[S4R3D7_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474192}; Flags: Fragment;+++[S4R3V1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474775}; Flags: Fragment;+++[S4R3W3_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474809}; Flags: Fragment;"]
[10370,"'CITED2'",3639,3674,3362,3558.33333333333,"04137///Mitophagy - animal","H01926///Ventricular septal defect (VSD)+++H00546///Atrial septal defect",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin","GO:0046332///SMAD binding+++GO:0050693///LBD domain binding+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding+++GO:0035035///histone acetyltransferase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding","GO:0007417///central nervous system development+++GO:0070986///left/right axis specification+++GO:0060411///cardiac septum morphogenesis+++GO:0009612///response to mechanical stimulus+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0034405///response to fluid shear stress+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030851///granulocyte differentiation+++GO:0003197///endocardial cushion development+++GO:0007507///heart development+++GO:0008584///male gonad development+++GO:0061308///cardiac neural crest cell development involved in heart development+++GO:0043066///negative regulation of apoptotic process+++GO:2000020///positive regulation of male gonad development+++GO:0060349///bone morphogenesis+++GO:0021602///cranial nerve morphogenesis+++GO:0048821///erythrocyte development+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0048538///thymus development+++GO:0007530///sex determination+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0001947///heart looping+++GO:0045787///positive regulation of cell cycle+++GO:0035914///skeletal muscle cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0061371///determination of heart left/right asymmetry+++GO:0001944///vasculature development+++GO:0001889///liver development+++GO:0001701///in utero embryonic development+++GO:0007422///peripheral nervous system development+++GO:0001829///trophectodermal cell differentiation+++GO:0008283///cell proliferation+++GO:0001570///vasculogenesis+++GO:0001568///blood vessel development+++GO:0001841///neural tube formation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0030325///adrenal gland development+++GO:0003156///regulation of animal organ formation+++GO:0035802///adrenal cortex formation+++GO:0003151///outflow tract morphogenesis+++GO:0043627///response to estrogen+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:1900164///nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0071363///cellular response to growth factor stimulus+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0007275///multicellular organism development+++GO:0030336///negative regulation of cell migration+++GO:0007368///determination of left/right symmetry+++GO:0060412///ventricular septum morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001666///response to hypoxia+++GO:0048536///spleen development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002521///leukocyte differentiation+++GO:0001843///neural tube closure+++GO:0007569///cell aging+++GO:0001892///embryonic placenta development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0003281///ventricular septum development+++GO:0061156///pulmonary artery morphogenesis+++GO:0046697///decidualization+++GO:0060136///embryonic process involved in female pregnancy","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2","[CITE2_HUMAN|Reviewed]RecName: Full=Cbp/p300-interacting transactivator 2; AltName: Full=MSG-related protein 1; Short=MRG-1; AltName: Full=P35srj;+++[A0A0A0MTM3_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator 2 {ECO:0000313|Ensembl:ENSP00000444198};+++[D9ZGF1_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 {ECO:0000313|EMBL:ADL14510.1}; SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, isoform CRA_d {ECO:0000313|EMBL:EAW47894.1};"]
[10371,"'SEMA3A'",346,338,360,348,"04360///Axon guidance","H00556///CHARGE syndrome+++H00255///Hypogonadotropic hypogonadism","M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin","GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030424///axon+++GO:0005887///integral component of plasma membrane+++GO:0030425///dendrite","GO:0045499///chemorepellent activity+++GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding","GO:0002027///regulation of heart rate+++GO:0001764///neuron migration+++GO:0021637///trigeminal nerve structural organization+++GO:0050919///negative chemotaxis+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:0021675///nerve development+++GO:0006915///apoptotic process+++GO:0048846///axon extension involved in axon guidance+++GO:0007411///axon guidance+++GO:0048813///dendrite morphogenesis+++GO:0030517///negative regulation of axon extension+++GO:0021785///branchiomotor neuron axon guidance+++GO:0060385///axonogenesis involved in innervation+++GO:0007413///axonal fasciculation+++GO:0048841///regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:1903045///neural crest cell migration involved in sympathetic nervous system development+++GO:0061549///sympathetic ganglion development+++GO:0001755///neural crest cell migration+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:0061551///trigeminal ganglion development+++GO:0046330///positive regulation of JNK cascade+++GO:0021612///facial nerve structural organization+++GO:2001224///positive regulation of neuron migration+++GO:0021772///olfactory bulb development+++GO:0030335///positive regulation of cell migration+++GO:0097490///sympathetic neuron projection extension+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0150020///basal dendrite arborization+++GO:0010633///negative regulation of epithelial cell migration+++GO:0048880///sensory system development+++GO:0010977///negative regulation of neuron projection development+++GO:0008045///motor neuron axon guidance+++GO:0007275///multicellular organism development+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:2000020///positive regulation of male gonad development+++GO:0097491///sympathetic neuron projection guidance+++GO:1903375///facioacoustic ganglion development+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030154///cell differentiation+++GO:0036486///ventral trunk neural crest cell migration+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048485///sympathetic nervous system development","semaphorin 3A","[SEM3A_HUMAN|Reviewed]RecName: Full=Semaphorin-3A; AltName: Full=Semaphorin III; Short=Sema III; Flags: Precursor;+++[A0A0C4DG50_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000402093}; Flags: Fragment;+++[C9J9C4_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000391900}; Flags: Fragment;+++[C9JD25_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000404800}; Flags: Fragment;+++[Q75MQ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAS02028.1}; Flags: Fragment;+++[Q86UJ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAP22350.1}; Flags: Fragment;"]
[10376,"'TUBA1B'",11442.08,10706.19,11180.6,11109.6233333333,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection+++04530///Tight junction+++04210///Apoptosis","H00058///Amyotrophic lateral sclerosis (ALS)+++H00268///Lissencephaly (LIS)+++H00271///Polymicrogyria",null,null,"GO:0005874///microtubule+++GO:0045121///membrane raft+++GO:0015630///microtubule cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath","GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007017///microtubule-based process+++GO:0000278///mitotic cell cycle+++GO:0071353///cellular response to interleukin-4+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0000226///microtubule cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0051301///cell division","tubulin alpha 1b","[TBA1B_HUMAN|Reviewed]RecName: Full=Tubulin alpha-1B chain; AltName: Full=Alpha-tubulin ubiquitous; AltName: Full=Tubulin K-alpha-1; AltName: Full=Tubulin alpha-ubiquitous chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1B chain;+++[F8VRK0_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448648}; Flags: Fragment;+++[F8VU66_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448045};+++[F8VVB9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449325}; Flags: Fragment;+++[F8VWV9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449460}; Flags: Fragment;+++[F8VX09_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449748}; Flags: Fragment;"]
[10379,"'IRF9'",792,722,693,735.666666666667,"05164///Influenza A+++04630///Jak-STAT signaling pathway+++05160///Hepatitis C+++05162///Measles+++05165///Human papillomavirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05168///Herpes simplex infection+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++05203///Viral carcinogenesis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity","GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0007166///cell surface receptor signaling pathway+++GO:0060337///type I interferon signaling pathway","interferon regulatory factor 9","[IRF9_HUMAN|Reviewed]RecName: Full=Interferon regulatory factor 9; Short=IRF-9; AltName: Full=IFN-alpha-responsive transcription factor subunit; AltName: Full=ISGF3 p48 subunit; AltName: Full=Interferon-stimulated gene factor 3 gamma; Short=ISGF-3 gamma; AltName: Full=Transcriptional regulator ISGF3 subunit gamma;+++[H0YMB0_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453534};+++[H0YMB6_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453540}; Flags: Fragment;+++[H0YNM9_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454078};+++[H0YNP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454095}; Flags: Fragment;+++[H7BXP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000313529}; Flags: Fragment;"]
[10380,"'BPNT1'",256,276,268,266.666666666667,"01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++00920///Sulfur metabolism+++01130///Biosynthesis of antibiotics",null,null,"R00508///3'-phospho-5'-adenylyl sulfate 3'-phosphohydrolase   3'-Phosphoadenylyl sulfate + H2O <=> Adenylyl sulfate + Orthophosphate+++R00188///adenosine-3',5'-bisphosphate 3'-phosphohydrolase   Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate","GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005615///extracellular space","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008441///3'(2'),5'-bisphosphate nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0019864///IgG binding+++GO:0004190///aspartic-type endopeptidase activity+++GO:0046983///protein dimerization activity+++GO:0003779///actin binding","GO:0070233///negative regulation of T cell apoptotic process+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0010628///positive regulation of gene expression+++GO:0055085///transmembrane transport+++GO:0001895///retina homeostasis+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0007399///nervous system development+++GO:0016311///dephosphorylation+++GO:0006508///proteolysis+++GO:0046854///phosphatidylinositol phosphorylation","3'(2'), 5'-bisphosphate nucleotidase 1","[BPNT1_HUMAN|Reviewed]RecName: Full=3'(2'),5'-bisphosphate nucleotidase 1; EC=3.1.3.7; AltName: Full=Bisphosphate 3'-nucleotidase 1; AltName: Full=PAP-inositol 1,4-phosphatase; Short=PIP;+++[A6NF51_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000346862};+++[B7Z9J7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78861, highly similar to 3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|EMBL:BAH14333.1};+++[F8VRY7_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000448740}; Flags: Fragment;+++[F8VVW8_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000449883}; Flags: Fragment;+++[F8VZG4_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446850}; Flags: Fragment;+++[F8W1J0_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446953}; Flags: Fragment;+++[V9HWF9_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 20 {ECO:0000313|EMBL:ACJ13648.1}; SubName: Full=Testicular tissue protein Li 29 {ECO:0000313|EMBL:AEE60942.1};"]
[10381,"'TUBB3'",7692.09,6419.16,6315.04,6808.76333333333,"04540///Gap junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H01579///Congenital symmetric circumferential skin creases+++H01740///Macrothrombocytopenia+++H00679///Hypomyelinating leukodystrophy+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect+++H00271///Polymicrogyria+++H01881///Complex cortical dysplasia with other brain malformations",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030424///axon","GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007017///microtubule-based process+++GO:0007411///axon guidance+++GO:0000278///mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0030182///neuron differentiation+++GO:0007010///cytoskeleton organization","tubulin beta 3 class III","[TBB3_HUMAN|Reviewed]RecName: Full=Tubulin beta-3 chain; AltName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin beta-III;+++[G3V2A3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[G3V2N6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_d {ECO:0000313|EMBL:EAW66672.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450765};+++[G3V2R8_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_e {ECO:0000313|EMBL:EAW66673.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450822};+++[G3V3J6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_b {ECO:0000313|EMBL:EAW66670.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451276};+++[G3V3R4_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_c {ECO:0000313|EMBL:EAW66671.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451378};+++[G3V3W7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451465};+++[G3V4U2_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451985};+++[G3V542_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452166}; Flags: Fragment;+++[G3V5W4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452554};+++[Q3ZCR3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q53G92_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q9BV28_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;"]
[10382,"'TUBB4A'",7885,9088,8484,8485.66666666667,"05130///Pathogenic Escherichia coli infection+++04540///Gap junction+++04145///Phagosome","H00679///Hypomyelinating leukodystrophy+++H01740///Macrothrombocytopenia+++H01881///Complex cortical dysplasia with other brain malformations+++H01897///Oocyte maturation defect+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01579///Congenital symmetric circumferential skin creases+++H00271///Polymicrogyria",null,null,"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005929///cilium+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0033269///internode region of axon+++GO:0042995///cell projection+++GO:0005930///axoneme+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005509///calcium ion binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007010///cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0031115///negative regulation of microtubule polymerization","tubulin beta 4A class IVa","[TBB4A_HUMAN|Reviewed]RecName: Full=Tubulin beta-4A chain; AltName: Full=Tubulin 5 beta; AltName: Full=Tubulin beta-4 chain;+++[M0QX14_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000468843};+++[M0QY37_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469560};+++[M0QY85_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469660}; Flags: Fragment;+++[M0QYM7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469936}; Flags: Fragment;+++[M0QZL7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000470627}; Flags: Fragment;+++[M0R042_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R0M1_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471320};+++[M0R0X0_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471503};+++[M0R1I1_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R278_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472375}; Flags: Fragment;+++[M0R2D3_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472481}; Flags: Fragment;+++[M0R2T4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472795};"]
[10383,"'TUBB4B'",6737.93,6858.36,6277.79,6624.69333333333,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection","H01579///Congenital symmetric circumferential skin creases+++H00679///Hypomyelinating leukodystrophy+++H01881///Complex cortical dysplasia with other brain malformations+++H01740///Macrothrombocytopenia+++H00271///Polymicrogyria+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect",null,null,"GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:1903561///extracellular vesicle+++GO:0035578///azurophil granule lumen+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005576///extracellular region","GO:0005200///structural constituent of cytoskeleton+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0042288///MHC class I protein binding+++GO:0005525///GTP binding+++GO:0051082///unfolded protein binding+++GO:0000166///nucleotide binding","GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0043312///neutrophil degranulation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0000226///microtubule cytoskeleton organization","tubulin beta 4B class IVb","[TBB4B_HUMAN|Reviewed]RecName: Full=Tubulin beta-4B chain; AltName: Full=Tubulin beta-2 chain; AltName: Full=Tubulin beta-2C chain;+++[Q8IZ29_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q8N6N5_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q96HX0_HUMAN|Unreviewed]SubName: Full=TUBB2C protein {ECO:0000313|EMBL:AAH08006.1}; Flags: Fragment;"]
[10384,"'BTN3A3'",58.35,56.26,81.68,65.43,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding","GO:0050852///T cell receptor signaling pathway+++GO:0050776///regulation of immune response+++GO:0002376///immune system process+++GO:0006366///transcription by RNA polymerase II+++GO:0002250///adaptive immune response+++GO:0015031///protein transport+++GO:0002456///T cell mediated immunity+++GO:0001701///in utero embryonic development","butyrophilin subfamily 3 member A3","[BT3A3_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 3 member A3; Flags: Precursor;+++[A0A024R042_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 3, member A3, isoform CRA_b {ECO:0000313|EMBL:EAW55574.1};+++[A0A089GIA6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 secreted isoform {ECO:0000313|EMBL:AIP98384.1};+++[C9J3Q8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417234}; Flags: Fragment;+++[C9J877_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417717}; Flags: Fragment;+++[C9JNZ3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420339}; Flags: Fragment;+++[C9JQT8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420147}; Flags: Fragment;+++[C9JUV8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419445}; Flags: Fragment;+++[C9JVU4_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419312}; Flags: Fragment;+++[C9JZT5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419736}; Flags: Fragment;+++[D6RDG3_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;+++[H0Y9Y1_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;"]
[10385,"'BTN2A2'",258,401,302,320.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0050776///regulation of immune response+++GO:0031324///negative regulation of cellular metabolic process+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0050710///negative regulation of cytokine secretion","butyrophilin subfamily 2 member A2","[BT2A2_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 2 member A2; Flags: Precursor;+++[A0A024R038_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 2, member A2, isoform CRA_a {ECO:0000313|EMBL:EAW55564.1};+++[C9IY66_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418857}; Flags: Fragment;+++[C9IZY2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418965}; Flags: Fragment;+++[C9J8J5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418176}; Flags: Fragment;+++[C9J8R3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417676}; Flags: Fragment;+++[C9JAJ6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417511}; Flags: Fragment;+++[C9JWH2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000419226}; Flags: Fragment;+++[F8WC65_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418657};+++[H7C4E8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417129}; Flags: Fragment;"]
[10388,"'SYCP2'",5,5,6,5.33333333333333,{"$nulls":4},"GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000800///lateral element+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0000795///synaptonemal complex+++GO:0005694///chromosome+++GO:0032991///protein-containing complex","GO:0033814///propanoyl-CoA C-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0005102///signaling receptor binding+++GO:0050632///propionyl-CoA C2-trimethyltridecanoyltransferase activity+++GO:0000062///fatty-acyl-CoA binding+++GO:0003824///catalytic activity+++GO:0008289///lipid binding+++GO:0046982///protein heterodimerization activity+++GO:0070538///oleic acid binding","GO:0006701///progesterone biosynthetic process+++GO:1901373///lipid hydroperoxide transport+++GO:0072659///protein localization to plasma membrane+++GO:0007049///cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0007140///male meiotic nuclear division+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0045940///positive regulation of steroid metabolic process+++GO:0007143///female meiotic nuclear division+++GO:0036109///alpha-linolenic acid metabolic process+++GO:0009566///fertilization+++GO:0006699///bile acid biosynthetic process+++GO:0032385///positive regulation of intracellular cholesterol transport+++GO:0006869///lipid transport+++GO:0007031///peroxisome organization+++GO:0015914///phospholipid transport+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0051301///cell division+++GO:0006694///steroid biosynthetic process+++GO:0009887///animal organ morphogenesis+++GO:0048808///male genitalia morphogenesis+++GO:0051321///meiotic cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0006625///protein targeting to peroxisome","synaptonemal complex protein 2","[SYCP2_HUMAN|Reviewed]RecName: Full=Synaptonemal complex protein 2; Short=SCP-2; AltName: Full=Synaptonemal complex lateral element protein; Short=hsSCP2;+++[A2A2M9_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000399300}; Flags: Fragment;+++[A2A340_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000404358}; Flags: Fragment;+++[A2A341_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000402456}; Flags: Fragment;+++[A6QL60_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAI46799.1}; Flags: Fragment;+++[H0YCB0_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000431279}; Flags: Fragment;+++[H0YD06_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000432645}; Flags: Fragment;+++[H0YEU8_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000436581}; Flags: Fragment;+++[H0YF61_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000437317}; Flags: Fragment;+++[L0R5C7_HUMAN|Unreviewed]SubName: Full=Alternative protein SCP2 {ECO:0000313|EMBL:CCO13809.1};+++[Q8IWA1_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAH40566.1}; Flags: Fragment;"]
[10389,"'SCML2'",13,11,8,10.6666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0031519///PcG protein complex","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0009653///anatomical structure morphogenesis","Scm polycomb group protein like 2","[SCML2_HUMAN|Reviewed]RecName: Full=Sex comb on midleg-like protein 2;+++[H0Y6S1_HUMAN|Unreviewed]SubName: Full=Sex comb on midleg-like protein 2 {ECO:0000313|Ensembl:ENSP00000407315}; Flags: Fragment;"]
[1039,"'CDR2'",1415,1610,1367,1464,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","cerebellar degeneration related protein 2","[CDR2_HUMAN|Reviewed]RecName: Full=Cerebellar degeneration-related protein 2; AltName: Full=Major Yo paraneoplastic antigen; AltName: Full=Paraneoplastic cerebellar degeneration-associated antigen;+++[H3BN65_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000454706}; Flags: Fragment;+++[H3BQS4_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000455915};+++[H3BTR1_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457289}; Flags: Fragment;+++[H3BU23_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457432}; Flags: Fragment;+++[H3BUE0_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457596}; Flags: Fragment;"]
[10390,"'CEPT1'",114,129,127,123.333333333333,"01100///Metabolic pathways+++00564///Glycerophospholipid metabolism+++00440///Phosphonate and phosphinate metabolism+++00565///Ether lipid metabolism+++01110///Biosynthesis of secondary metabolites","H00481///Cone-rod dystrophy and cone dystrophy","M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE+++M00090///Phosphatidylcholine (PC) biosynthesis, choline => PC","R04321///CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase   CDP-choline + 1-Alkyl-2-acetyl-sn-glycerol <=> CMP + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine+++R04922///CMP-N-trimethyl-2-aminoethylphosphonate:1,2-diacylglycerol (N-trimethyl-2-aminoethylphosphonyl)transferase   CMP-N-trimethyl-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate+++R02057///CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine+++R07389///1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP+++R04920///CMP-2-aminoethylphosphonate:1,2-diacylglycerol (2-aminoethylphosphonyl)transferase   CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate+++R07384///O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine+++R01321///CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase   CDP-choline + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylcholine+++R06364///CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine","GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane","GO:0004142///diacylglycerol cholinephosphotransferase activity+++GO:0046872///metal ion binding+++GO:0004307///ethanolaminephosphotransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups","GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006657///CDP-choline pathway+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process","choline/ethanolamine phosphotransferase 1","[CEPT1_HUMAN|Reviewed]RecName: Full=Choline/ethanolaminephosphotransferase 1; Short=hCEPT1; EC=2.7.8.1; EC=2.7.8.2;+++[A0A024R0C0_HUMAN|Unreviewed]SubName: Full=Choline/ethanolamine phosphotransferase 1, isoform CRA_b {ECO:0000313|EMBL:EAW56472.1};+++[A0A0C4DGS9_HUMAN|Unreviewed]SubName: Full=Choline/ethanolaminephosphotransferase 1 {ECO:0000313|Ensembl:ENSP00000477632};"]
[10391,"'CORO2B'",449,633,556,546,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding","GO:0030036///actin cytoskeleton organization","coronin 2B","[COR2B_HUMAN|Reviewed]RecName: Full=Coronin-2B; AltName: Full=Coronin-like protein C; Short=Clipin-C; AltName: Full=Protein FC96;"]
[103910,"'MYL12B'",4738,3569,4058,4121.66666666667,"04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++04611///Platelet activation",{"$nulls":3},"GO:0099738///cell cortex region+++GO:0045177///apical part of cell+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005903///brush border+++GO:0001725///stress fiber+++GO:0070062///extracellular exosome","GO:0032036///myosin heavy chain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0008360///regulation of cell shape","myosin light chain 12B","[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;"]
[10392,"'NOD1'",98,105,117,106.666666666667,"04621///NOD-like receptor signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05133///Pertussis+++05131///Shigellosis","H01358///Atopic dermatitis",null,"R03749///(5-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxoproline-forming) (5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid+++R02743///gamma-L-glutamyl-L-cysteine gamma-glutamyl cyclotransferase (5-oxoproline-forming) gamma-L-Glutamyl-L-cysteine <=> 5-Oxoproline + L-Cysteine","GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0042834///peptidoglycan binding+++GO:0050700///CARD domain binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0042802///identical protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0000187///activation of MAPK activity+++GO:0002376///immune system process+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0009595///detection of biotic stimulus+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0016045///detection of bacterium+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0042981///regulation of apoptotic process+++GO:0007165///signal transduction+++GO:0042742///defense response to bacterium+++GO:1904417///positive regulation of xenophagy+++GO:0006915///apoptotic process+++GO:0071225///cellular response to muramyl dipeptide+++GO:0050830///defense response to Gram-positive bacterium+++GO:0007254///JNK cascade+++GO:0042228///interleukin-8 biosynthetic process+++GO:0006954///inflammatory response+++GO:0035556///intracellular signal transduction+++GO:0006952///defense response+++GO:0010942///positive regulation of cell death+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","nucleotide binding oligomerization domain containing 1","[NOD1_HUMAN|Reviewed]RecName: Full=Nucleotide-binding oligomerization domain-containing protein 1; AltName: Full=Caspase recruitment domain-containing protein 4;+++[A0A024RA73_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4 {ECO:0000313|EMBL:EAL24453.1}; SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW93949.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 1 {ECO:0000313|EMBL:ALQ33972.1};+++[A0A0S2Z4W5_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 2 {ECO:0000313|EMBL:ALQ33973.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 3 {ECO:0000313|EMBL:ALQ33974.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 4 {ECO:0000313|EMBL:ALQ33975.1};+++[A0A1B0GX71_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000399505}; Flags: Fragment;+++[C9J8X8_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410917}; Flags: Fragment;+++[G3XAL1_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_c {ECO:0000313|EMBL:EAW93948.1}; SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000416946};"]
[10393,"'ANAPC10'",58,73,53,61.3333333333333,"04114///Oocyte meiosis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04111///Cell cycle - yeast+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex","GO:0016887///ATPase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0005506///iron ion binding+++GO:0060698///endoribonuclease inhibitor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding","GO:0007049///cell cycle+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0051301///cell division+++GO:0016567///protein ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition","anaphase promoting complex subunit 10","[APC10_HUMAN|Reviewed]RecName: Full=Anaphase-promoting complex subunit 10; Short=APC10; AltName: Full=Cyclosome subunit 10;+++[A0A286YEY6_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000493135};+++[D6R9Q5_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423223}; Flags: Fragment;+++[D6RA92_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423043}; Flags: Fragment;+++[D6RB36_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000424463}; Flags: Fragment;+++[D6RD74_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000425459};+++[Q4W5I2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein APC10 {ECO:0000313|EMBL:AAY40941.1}; Flags: Fragment;"]
[10395,"'DLC1'",586,679,681,648.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0071682///endocytic vesicle lumen+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0070062///extracellular exosome+++GO:1904724///tertiary granule lumen+++GO:0005615///extracellular space+++GO:0072562///blood microparticle+++GO:0035580///specific granule lumen+++GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0030492///hemoglobin binding+++GO:0016209///antioxidant activity+++GO:0005515///protein binding","GO:0042742///defense response to bacterium+++GO:0002376///immune system process+++GO:0042542///response to hydrogen peroxide+++GO:0006952///defense response+++GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis+++GO:0006953///acute-phase response+++GO:0098869///cellular oxidant detoxification+++GO:0043312///neutrophil degranulation+++GO:2000296///negative regulation of hydrogen peroxide catabolic process+++GO:0002526///acute inflammatory response+++GO:0010033///response to organic substance+++GO:0010942///positive regulation of cell death+++GO:0051354///negative regulation of oxidoreductase activity","DLC1 Rho GTPase activating protein","[RHG07_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 7; AltName: Full=Deleted in liver cancer 1 protein; Short=DLC-1; AltName: Full=HP protein; AltName: Full=Rho-type GTPase-activating protein 7; AltName: Full=START domain-containing protein 12; Short=StARD12; AltName: Full=StAR-related lipid transfer protein 12;+++[A0A087WU08_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000478279};+++[A0A0J9YWS8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000488100}; Flags: Fragment;+++[A0A0U4DJF7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40940.1}; Flags: Fragment;+++[A0A0U4DKQ8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40945.1}; Flags: Fragment;+++[A0A0U4ERW6_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40957.1}; Flags: Fragment;+++[A0A0U4EXB4_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40958.1}; Flags: Fragment;+++[A0A2X0SYX6_HUMAN|Unreviewed]SubName: Full=DLC1 {ECO:0000313|EMBL:SPT35739.1}; Flags: Fragment;+++[A8K119_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76742, highly similar to Homo sapiens deleted in liver cancer 1 (DLC1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF82423.1};+++[E5RI70_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000429537}; Flags: Fragment;+++[H0Y300_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000350406};+++[H3BMJ7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000454413};+++[H3BS21_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000456503}; Flags: Fragment;+++[J3KRH2_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000461999}; Flags: Fragment;+++[J3KSV1_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000462662}; Flags: Fragment;+++[J3QLC9_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463491}; Flags: Fragment;+++[J3QQI8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463755};+++[J3QR68_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000464070}; Flags: Fragment;+++[Q14552_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:AAA52686.1}; Flags: Fragment;+++[Q45XF9_HUMAN|Unreviewed]SubName: Full=Deleted in liver cancer 1 variant 2 {ECO:0000313|EMBL:AAZ32941.1}; Flags: Fragment;+++[Q6NSB4_HUMAN|Unreviewed]SubName: Full=HP protein {ECO:0000313|EMBL:AAH70299.1};+++[R4GMP5_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000473289}; Flags: Fragment;"]
[10396,"'ATP8A1'",335,467,351,384.333333333333,null,"H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0035579///specific granule membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005802///trans-Golgi network+++GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0042584///chromaffin granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0005524///ATP binding+++GO:0019829///cation-transporting ATPase activity","GO:0030335///positive regulation of cell migration+++GO:0061092///positive regulation of phospholipid translocation+++GO:0034220///ion transmembrane transport+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport+++GO:0007612///learning+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0043312///neutrophil degranulation+++GO:0006869///lipid transport","ATPase phospholipid transporting 8A1","[AT8A1_HUMAN|Reviewed]RecName: Full=Phospholipid-transporting ATPase IA; EC=3.6.3.1; AltName: Full=ATPase class I type 8A member 1; AltName: Full=Chromaffin granule ATPase II; AltName: Full=P4-ATPase flippase complex alpha subunit ATP8A1;+++[H0Y8I6_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000421164}; Flags: Fragment;+++[H0YAA1_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426495}; Flags: Fragment;+++[H0YAF4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426935}; Flags: Fragment;+++[H0YAJ4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000427295}; Flags: Fragment;+++[Q4G1C1_HUMAN|Unreviewed]SubName: Full=ATP8A1 protein {ECO:0000313|EMBL:AAH20943.1}; SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426636};"]
[10397,"'NDRG1'",1348,2229,1704,1760.33333333333,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0005815///microtubule organizing center+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton","GO:0017137///Rab GTPase binding+++GO:0043015///gamma-tubulin binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0045576///mast cell activation+++GO:0007165///signal transduction+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0099173///postsynapse organization+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0071456///cellular response to hypoxia+++GO:0042981///regulation of apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010038///response to metal ion+++GO:0042127///regulation of cell proliferation","N-myc downstream regulated 1","[NDRG1_HUMAN|Reviewed]RecName: Full=Protein NDRG1; AltName: Full=Differentiation-related gene 1 protein; Short=DRG-1; AltName: Full=N-myc downstream-regulated gene 1 protein; AltName: Full=Nickel-specific induction protein Cap43; AltName: Full=Reducing agents and tunicamycin-responsive protein; Short=RTP; AltName: Full=Rit42;+++[A0A024R9I3_HUMAN|Unreviewed]SubName: Full=N-myc downstream regulated gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW92166.1};+++[B3KWB2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ42719 fis, clone BRAMY3010492, highly similar to Protein NDRG1 {ECO:0000313|EMBL:BAG54074.1};+++[E5RG99_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428802}; Flags: Fragment;+++[E5RGG6_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000430171}; Flags: Fragment;+++[E5RGM5_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429994}; Flags: Fragment;+++[E5RH82_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429840}; Flags: Fragment;+++[E5RI76_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429524}; Flags: Fragment;+++[E5RIM2_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429380};+++[E5RIR1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428384}; Flags: Fragment;+++[E5RIV1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428345}; Flags: Fragment;+++[E5RJ98_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429172};+++[E5RJY1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000431057};+++[E5RK17_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428991}; Flags: Fragment;+++[E7ESM1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429007};+++[Q8N959_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38330 fis, clone FCBBF3025280, highly similar to NDRG1 PROTEIN {ECO:0000313|EMBL:BAC04597.1};"]
[10398,"'MYL9'",31577,21581,20434,24530.6666666667,"04670///Leukocyte transendothelial migration+++04270///Vascular smooth muscle contraction+++04530///Tight junction+++04921///Oxytocin signaling pathway+++04024///cAMP signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005829///cytosol+++GO:0001725///stress fiber+++GO:0030018///Z disc+++GO:0005859///muscle myosin complex","GO:0046872///metal ion binding+++GO:0008307///structural constituent of muscle+++GO:0032036///myosin heavy chain binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0070527///platelet aggregation","myosin light chain 9","[MYL9_HUMAN|Reviewed]RecName: Full=Myosin regulatory light polypeptide 9; AltName: Full=20 kDa myosin light chain; Short=LC20; AltName: Full=MLC-2C; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 9; AltName: Full=Myosin regulatory light chain MRLC1;+++[Q6IBG1_HUMAN|Unreviewed]SubName: Full=MYL9 protein {ECO:0000313|EMBL:CAG33124.1};"]
[10399,"'RACK1'",24372,25955,23291,24539.3333333333,"05162///Measles",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005840///ribosome+++GO:1990630///IRE1-RACK1-PP2A complex+++GO:0001891///phagocytic cup+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0015935///small ribosomal subunit+++GO:0042995///cell projection+++GO:0005654///nucleoplasm+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0044297///cell body+++GO:0030496///midbody+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043204///perikaryon+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0045296///cadherin binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0003723///RNA binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0008200///ion channel inhibitor activity+++GO:0030292///protein tyrosine kinase inhibitor activity+++GO:0043022///ribosome binding+++GO:0042169///SH2 domain binding+++GO:0005080///protein kinase C binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0019899///enzyme binding+++GO:0030332///cyclin binding+++GO:0019903///protein phosphatase binding+++GO:0035591///signaling adaptor activity+++GO:0042803///protein homodimerization activity","GO:0072344///rescue of stalled ribosome+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0032464///positive regulation of protein homooligomerization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006412///translation+++GO:0071363///cellular response to growth factor stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:1900102///negative regulation of endoplasmic reticulum unfolded protein response+++GO:0017148///negative regulation of translation+++GO:0032880///regulation of protein localization+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0043065///positive regulation of apoptotic process+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0007369///gastrulation+++GO:0040008///regulation of growth+++GO:0016567///protein ubiquitination+++GO:0030308///negative regulation of cell growth+++GO:0050765///negative regulation of phagocytosis+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0048511///rhythmic process+++GO:0043547///positive regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0006915///apoptotic process+++GO:2000304///positive regulation of ceramide biosynthetic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010629///negative regulation of gene expression+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:0006417///regulation of translation+++GO:2000543///positive regulation of gastrulation+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051726///regulation of cell cycle+++GO:0051302///regulation of cell division+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0043473///pigmentation+++GO:0071333///cellular response to glucose stimulus","receptor for activated C kinase 1","[RACK1_HUMAN|Reviewed]RecName: Full=Receptor of activated protein C kinase 1; AltName: Full=Cell proliferation-inducing gene 21 protein; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1; AltName: Full=Guanine nucleotide-binding protein subunit beta-like protein 12.3; AltName: Full=Human lung cancer oncogene 7 protein; Short=HLC-7; AltName: Full=Receptor for activated C kinase; AltName: Full=Small ribosomal subunit protein RACK1 {ECO:0000303|PubMed:24524803}; Contains: RecName: Full=Receptor of activated protein C kinase 1, N-terminally processed; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed;+++[D6R909_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422198};+++[D6R9L0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000423569}; Flags: Fragment;+++[D6R9Z1_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422029}; Flags: Fragment;+++[D6RAC2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422768};+++[D6RAU2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424760};+++[D6RBD0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424237}; Flags: Fragment;+++[D6RDI0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000420936};+++[D6REE5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000425008}; Flags: Fragment;+++[D6RF23_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426708};+++[D6RFX4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421416}; Flags: Fragment;+++[D6RFZ9_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421356}; Flags: Fragment;+++[D6RGK8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426270};+++[D6RHH4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426101};+++[D6RHJ5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426046};+++[E9KL35_HUMAN|Unreviewed]SubName: Full=Epididymis tissue sperm binding protein Li 3a {ECO:0000313|EMBL:ADU87634.1};+++[E9PD14_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426111};+++[H0Y8R5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421838}; Flags: Fragment;+++[H0Y8W2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422316}; Flags: Fragment;+++[H0Y9P0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424654}; Flags: Fragment;+++[H0YAF8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426960}; Flags: Fragment;+++[H0YAM7_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000427677}; Flags: Fragment;+++[I3QNU9_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein beta polypeptide 2-like 1 {ECO:0000313|EMBL:AFK13122.1}; Flags: Fragment;+++[J3KPE3_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000366013};"]
[104,"'ADARB1'",259,285,264,269.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm","GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003729///mRNA binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0004000///adenosine deaminase activity","GO:0006382///adenosine to inosine editing+++GO:0051726///regulation of cell cycle+++GO:0051607///defense response to virus+++GO:0021610///facial nerve morphogenesis+++GO:0061744///motor behavior+++GO:0050884///neuromuscular process controlling posture+++GO:0030336///negative regulation of cell migration+++GO:0007274///neuromuscular synaptic transmission+++GO:0008285///negative regulation of cell proliferation+++GO:0006396///RNA processing+++GO:0035264///multicellular organism growth+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0097049///motor neuron apoptotic process+++GO:0060384///innervation+++GO:0006397///mRNA processing+++GO:0021618///hypoglossal nerve morphogenesis+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060415///muscle tissue morphogenesis+++GO:0021965///spinal cord ventral commissure morphogenesis+++GO:0045087///innate immune response+++GO:0016553///base conversion or substitution editing","adenosine deaminase, RNA specific B1","[RED1_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific editase 1; EC=3.5.4.37; AltName: Full=RNA-editing deaminase 1; AltName: Full=RNA-editing enzyme 1; AltName: Full=dsRNA adenosine deaminase;+++[A0A0A0MSG8_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000387480}; Flags: Fragment;+++[Q86XN4_HUMAN|Unreviewed]SubName: Full=RNA adenosine deaminase {ECO:0000313|EMBL:AAB18134.1};+++[Q8TCX7_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000478160}; SubName: Full=HCG2008433 {ECO:0000313|EMBL:EAX09362.1};"]
[1040,"'CDS1'",96,90,71,85.6666666666667,"04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,"M00093///Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE","R01799///CTP:phosphatidate cytidyltransferase   CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol","GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0004142///diacylglycerol cholinephosphotransferase activity","GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0007602///phototransduction+++GO:0007165///signal transduction+++GO:0006661///phosphatidylinositol biosynthetic process","CDP-diacylglycerol synthase 1","[CDS1_HUMAN|Reviewed]RecName: Full=Phosphatidate cytidylyltransferase 1; EC=2.7.7.41; AltName: Full=CDP-DAG synthase 1; AltName: Full=CDP-DG synthase 1; AltName: Full=CDP-diacylglycerol synthase 1; Short=CDS 1; AltName: Full=CDP-diglyceride pyrophosphorylase 1; AltName: Full=CDP-diglyceride synthase 1; AltName: Full=CTP:phosphatidate cytidylyltransferase 1;+++[A0A024RDG8_HUMAN|Unreviewed]RecName: Full=Phosphatidate cytidylyltransferase {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938}; EC=2.7.7.41 {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938};"]
[10400,"'PEMT'",660,609,622,630.333333333333,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites",null,"M00091///Phosphatidylcholine (PC) biosynthesis, PE => PC","R03424///S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine+++R02056///S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine+++R01320///S-adenosyl-L-methionine:phosphatidyl-N-dimethylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidylcholine","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0004603///phenylethanolamine N-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0042423///catecholamine biosynthetic process+++GO:0032259///methylation+++GO:0042418///epinephrine biosynthetic process","phosphatidylethanolamine N-methyltransferase","[PEMT_HUMAN|Reviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000255|HAMAP-Rule:MF_03216}; AltName: Full=PEMT2; AltName: Full=Phospholipid methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000255|HAMAP-Rule:MF_03216};+++[D3YTC7_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};+++[J3KTR2_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463112};+++[J3QLU8_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463713};+++[J3QRI3_HUMAN|Unreviewed]SubName: Full=Phenylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000464234};+++[Q6FHD9_HUMAN|Unreviewed]SubName: Full=PNMT protein {ECO:0000313|EMBL:CAG46614.1};+++[Q71UY0_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};"]
[10401,"'PIAS3'",1335,1395,1293,1341,"04120///Ubiquitin mediated proteolysis+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0030425///dendrite+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0045202///synapse+++GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0015459///potassium channel regulator activity+++GO:0051059///NF-kappaB binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0019789///SUMO transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0047485///protein N-terminus binding","GO:0009725///response to hormone+++GO:0071847///TNFSF11-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010629///negative regulation of gene expression+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0033234///negative regulation of protein sumoylation+++GO:0033235///positive regulation of protein sumoylation+++GO:0045838///positive regulation of membrane potential+++GO:0016925///protein sumoylation","protein inhibitor of activated STAT 3","[PIAS3_HUMAN|Reviewed]RecName: Full=E3 SUMO-protein ligase PIAS3; EC=2.3.2.-; AltName: Full=E3 SUMO-protein transferase PIAS3 {ECO:0000305}; AltName: Full=Protein inhibitor of activated STAT protein 3;+++[B3KNI3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14651 fis, clone NT2RP2002193, highly similar to Protein inhibitor of activated STAT protein 3 {ECO:0000313|EMBL:BAG51345.1};+++[E7ESB4_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000376766}; Flags: Fragment;+++[E9PHH8_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000358304};+++[Q6IAR4_HUMAN|Unreviewed]SubName: Full=PIAS3 protein {ECO:0000313|EMBL:CAG33371.1}; SubName: Full=Protein inhibitor of activated STAT3 {ECO:0000313|EMBL:AAP35684.1};+++[U3KQV1_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000476245}; Flags: Fragment;"]
[10402,"'ST3GAL6'",31,30,23,28,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++01100///Metabolic pathways",null,null,"R06026///CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-3-paragloboside+++R06037///CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI3NeuAc-nLc6Cer","GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0052798///beta-galactoside alpha-2,3-sialyltransferase activity","GO:0006464///cellular protein modification process+++GO:0006486///protein glycosylation+++GO:0071354///cellular response to interleukin-6+++GO:0009311///oligosaccharide metabolic process+++GO:0006664///glycolipid metabolic process+++GO:0009247///glycolipid biosynthetic process+++GO:0097503///sialylation+++GO:0018146///keratan sulfate biosynthetic process","ST3 beta-galactoside alpha-2,3-sialyltransferase 6","[SIA10_HUMAN|Reviewed]RecName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase; EC=2.4.99.-; AltName: Full=CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; AltName: Full=ST3Gal VI; Short=ST3GalVI; AltName: Full=Sialyltransferase 10;+++[A0A087WXB8_HUMAN|Unreviewed]SubName: Full=ST3 beta-galactoside alpha-2,3-sialyltransferase 6, isoform CRA_b {ECO:0000313|EMBL:EAW79851.1}; SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000480884};+++[C9IZL6_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418650}; Flags: Fragment;+++[C9J0E2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418896}; Flags: Fragment;+++[C9J480_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417201}; Flags: Fragment;+++[C9J9Y4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417584}; Flags: Fragment;+++[C9JMW7_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000420474};+++[C9JWI9_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419209}; Flags: Fragment;+++[C9JWJ3_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419202}; Flags: Fragment;+++[C9JXM2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419987}; Flags: Fragment;+++[F2Z2F4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417109};+++[F8WC98_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418581};"]
[10403,"'NDC80'",3,4,6,4.33333333333333,{"$nulls":4},"GO:0005694///chromosome+++GO:0031262///Ndc80 complex+++GO:0005829///cytosol+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005813///centrosome+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000777///condensed chromosome kinetochore","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0051383///kinetochore organization+++GO:1905342///positive regulation of protein localization to kinetochore+++GO:0000070///mitotic sister chromatid segregation+++GO:0000278///mitotic cell cycle+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0007059///chromosome segregation+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0051301///cell division+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0000132///establishment of mitotic spindle orientation","NDC80, kinetochore complex component","[NDC80_HUMAN|Reviewed]RecName: Full=Kinetochore protein NDC80 homolog; AltName: Full=Highly expressed in cancer protein; AltName: Full=Kinetochore protein Hec1; Short=HsHec1; AltName: Full=Kinetochore-associated protein 2; AltName: Full=Retinoblastoma-associated protein HEC;+++[A8K031_HUMAN|Unreviewed]SubName: Full=Kinetochore associated 2, isoform CRA_a {ECO:0000313|EMBL:EAX01696.1}; SubName: Full=NDC80 homolog, kinetochore complex component (S. cerevisiae) {ECO:0000313|EMBL:AAH35617.1}; SubName: Full=cDNA FLJ77925, highly similar to Homo sapiens kinetochore associated 2, mRNA {ECO:0000313|EMBL:BAF82085.1}; SubName: Full=cDNA, FLJ93683, Homo sapiens kinetochore associated 2 (KNTC2), mRNA {ECO:0000313|EMBL:BAG36001.1};+++[I3L0P0_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000458236}; Flags: Fragment;+++[I3L4G3_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000461227}; Flags: Fragment;+++[Q05DQ6_HUMAN|Unreviewed]SubName: Full=NDC80 protein {ECO:0000313|EMBL:AAH05239.1}; Flags: Fragment;+++[V9GYM9_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000476919}; Flags: Fragment;"]
[10404,"'CPQ'",601,508,481,530,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0042803///protein homodimerization activity+++GO:0008233///peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0070573///metallodipeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding","GO:0042246///tissue regeneration+++GO:0043171///peptide catabolic process+++GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation","carboxypeptidase Q","[CBPQ_HUMAN|Reviewed]RecName: Full=Carboxypeptidase Q; EC=3.4.17.-; AltName: Full=Lysosomal dipeptidase; AltName: Full=Plasma glutamate carboxypeptidase; Flags: Precursor;+++[A0A024R9B8_HUMAN|Unreviewed]SubName: Full=Plasma glutamate carboxypeptidase, isoform CRA_a {ECO:0000313|EMBL:EAW91758.1};+++[E5RH35_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429934}; Flags: Fragment;+++[E5RJA8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429146}; Flags: Fragment;+++[E5RJP8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431114}; Flags: Fragment;+++[E5RJZ7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431024}; Flags: Fragment;+++[H0YBB7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429134}; Flags: Fragment;"]
[10406,"'WFDC2'",41,61,69,57,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0010466///negative regulation of peptidase activity","WAP four-disulfide core domain 2","[WFDC2_HUMAN|Reviewed]RecName: Full=WAP four-disulfide core domain protein 2; AltName: Full=Epididymal secretory protein E4; AltName: Full=Major epididymis-specific protein E4; AltName: Full=Putative protease inhibitor WAP5; Flags: Precursor;+++[A8K2M3_HUMAN|Unreviewed]SubName: Full=WAP four-disulfide core domain 2, isoform CRA_c {ECO:0000313|EMBL:EAW75838.1}; SubName: Full=WAP four-disulfide core domain protein 2 {ECO:0000313|Ensembl:ENSP00000404760}; SubName: Full=cDNA FLJ76533, highly similar to Homo sapiens WAP four-disulfide core domain 2 (WFDC2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF82977.1};"]
[10408,"'MYCNOS'",1,0,2,1,"05202///Transcriptional misregulation in cancer","H00510///Feingold syndrome+++H00043///Neuroblastoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0031647///regulation of protein stability+++GO:0033673///negative regulation of kinase activity+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation","MYCN opposite strand","[NCYM_HUMAN|Reviewed]RecName: Full=N-cym protein; AltName: Full=N-myc opposite strand;"]
[10409,"'BASP1'",2971,2414,2351,2578.66666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0030426///growth cone+++GO:0031982///vesicle+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome","GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding","GO:0060421///positive regulation of heart growth+++GO:0060539///diaphragm development+++GO:0021762///substantia nigra development+++GO:0072075///metanephric mesenchyme development+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:2001076///positive regulation of metanephric ureteric bud development+++GO:0007356///thorax and anterior abdomen determination+++GO:0060231///mesenchymal to epithelial transition+++GO:0008406///gonad development+++GO:0045892///negative regulation of transcription, DNA-templated","brain abundant membrane attached signal protein 1","[BASP1_HUMAN|Reviewed]RecName: Full=Brain acid soluble protein 1; AltName: Full=22 kDa neuronal tissue-enriched acidic protein; AltName: Full=Neuronal axonal membrane protein NAP-22;+++[U3KQP0_HUMAN|Unreviewed]SubName: Full=Brain acid soluble protein 1 {ECO:0000313|Ensembl:ENSP00000476090}; Flags: Fragment;"]
[1041,"'CDSN'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0001533///cornified envelope+++GO:0030057///desmosome+++GO:0005911///cell-cell junction","GO:0042803///protein homodimerization activity","GO:0008544///epidermis development+++GO:0070268///cornification+++GO:0030216///keratinocyte differentiation+++GO:0003336///corneocyte desquamation+++GO:0007155///cell adhesion+++GO:1905716///negative regulation of cornification+++GO:0043589///skin morphogenesis+++GO:0098609///cell-cell adhesion","corneodesmosin","[CDSN_HUMAN|Reviewed]RecName: Full=Corneodesmosin; AltName: Full=S protein; Flags: Precursor;+++[D2IYL2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77254.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:ACZ95707.1};+++[G8JLG2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77255.1}; SubName: Full=Corneodesmosin {ECO:0000313|Ensembl:ENSP00000365465};+++[M1SWB8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77250.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AGG40963.1};+++[Q0EFA5_HUMAN|Unreviewed]SubName: Full=S protein {ECO:0000313|EMBL:BAF31283.1};+++[Q2L6G8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77252.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:BAE78625.1, ECO:0000313|Ensembl:ENSP00000373023};+++[Q7Z559_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94641.1}; Flags: Fragment;+++[Q7Z560_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94640.1}; Flags: Fragment;"]
[10410,"'IFITM3'",3435.99,3419.99,3512.99,3456.32333333333,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0032991///protein-containing complex+++GO:0005768///endosome+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0060337///type I interferon signaling pathway+++GO:0032897///negative regulation of viral transcription+++GO:0002376///immune system process+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0046597///negative regulation of viral entry into host cell+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0006955///immune response+++GO:0009615///response to virus+++GO:0051607///defense response to virus","interferon induced transmembrane protein 3","[IFM3_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 3; AltName: Full=Dispanin subfamily A member 2b; Short=DSPA2b; AltName: Full=Interferon-inducible protein 1-8U;+++[E9PS44_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000432108};+++[H9NKY4_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60318.1};+++[H9NL12_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60346.1};+++[H9NL19_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60353.1};+++[R4GNG9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000473645}; Flags: Fragment;"]
[10411,"'RAPGEF3'",22,38,30,30,"04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04720///Long-term potentiation+++04726///Serotonergic synapse+++04670///Leukocyte transendothelial migration+++04261///Adrenergic signaling in cardiomyocytes+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005902///microvillus+++GO:0030864///cortical actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0030175///filopodium","GO:0005515///protein binding+++GO:0030552///cAMP binding+++GO:0000166///nucleotide binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019904///protein domain specific binding+++GO:0017034///Rap guanyl-nucleotide exchange factor activity","GO:0019933///cAMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0051496///positive regulation of stress fiber assembly+++GO:0007264///small GTPase mediated signal transduction+++GO:0034242///negative regulation of syncytium formation by plasma membrane fusion+++GO:1901985///positive regulation of protein acetylation+++GO:0071320///cellular response to cAMP+++GO:0050796///regulation of insulin secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:0032486///Rap protein signal transduction+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:0061028///establishment of endothelial barrier+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0046827///positive regulation of protein export from nucleus+++GO:0043547///positive regulation of GTPase activity+++GO:0060143///positive regulation of syncytium formation by plasma membrane fusion","Rap guanine nucleotide exchange factor 3","[RPGF3_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 3; AltName: Full=Exchange factor directly activated by cAMP 1; AltName: Full=Exchange protein directly activated by cAMP 1; Short=EPAC 1; AltName: Full=Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; AltName: Full=cAMP-regulated guanine nucleotide exchange factor I; Short=cAMP-GEFI;+++[F8VRX1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448480};+++[F8VVJ6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449905};+++[F8VXK1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448804}; Flags: Fragment;+++[F8W0N0_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000446731}; Flags: Fragment;+++[H0YHS2_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000447691}; Flags: Fragment;+++[H0YIP6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449818}; Flags: Fragment;+++[Q569L6_HUMAN|Unreviewed]SubName: Full=RAPGEF3 protein {ECO:0000313|EMBL:AAH92404.2};+++[Q99777_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAB50216.1}; Flags: Fragment;"]
[10412,"'NSA2'",1335,1387,1115,1279,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing","NSA2, ribosome biogenesis homolog","[NSA2_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein NSA2 homolog; AltName: Full=Hairy cell leukemia protein 1; AltName: Full=TGF-beta-inducible nuclear protein 1;+++[A0A0A0MQZ6_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000296802};+++[H0YAI9_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000427266}; Flags: Fragment;+++[Q5J7U2_HUMAN|Unreviewed]SubName: Full=TGF beta-inducible nuclear protein 1 {ECO:0000313|EMBL:EAW95749.1}; SubName: Full=TGF-beta inducible nuclear protein {ECO:0000313|EMBL:AAS00024.1}; SubName: Full=cDNA, FLJ94393, Homo sapiens TGF beta-inducible nuclear protein 1 (TINP1), mRNA {ECO:0000313|EMBL:BAG36522.1};"]
[10413,"'YAP1'",1841,1851,1840,1844,"04391///Hippo signaling pathway - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species",null,"M00683///Hippo signaling",null,"GO:0005737///cytoplasm+++GO:0071148///TEAD-1-YAP complex+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071149///TEAD-2-YAP complex","GO:0046982///protein heterodimerization activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0070064///proline-rich region binding+++GO:0033613///activating transcription factor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0008022///protein C-terminus binding+++GO:0003714///transcription corepressor activity","GO:0010468///regulation of gene expression+++GO:0035019///somatic stem cell population maintenance+++GO:0048368///lateral mesoderm development+++GO:0030903///notochord development+++GO:0042127///regulation of cell proliferation+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0001570///vasculogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0048339///paraxial mesoderm development+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0035329///hippo signaling+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000737///negative regulation of stem cell differentiation+++GO:0060242///contact inhibition+++GO:0010837///regulation of keratinocyte proliferation+++GO:0060449///bud elongation involved in lung branching+++GO:0072091///regulation of stem cell proliferation+++GO:0032570///response to progesterone+++GO:0060487///lung epithelial cell differentiation+++GO:0008283///cell proliferation+++GO:0061026///cardiac muscle tissue regeneration+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:1902459///positive regulation of stem cell population maintenance+++GO:0046622///positive regulation of organ growth+++GO:0050767///regulation of neurogenesis+++GO:0003015///heart process+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0003143///embryonic heart tube morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001894///tissue homeostasis+++GO:0008284///positive regulation of cell proliferation+++GO:0071300///cellular response to retinoic acid+++GO:0030216///keratinocyte differentiation+++GO:0050847///progesterone receptor signaling pathway+++GO:0071480///cellular response to gamma radiation+++GO:0065003///protein-containing complex assembly","Yes associated protein 1","[YAP1_HUMAN|Reviewed]RecName: Full=Transcriptional coactivator YAP1; Short=Yes-associated protein 1; AltName: Full=Protein yorkie homolog; AltName: Full=Yes-associated protein YAP65 homolog;+++[A0A024R3E4_HUMAN|Unreviewed]SubName: Full=Yes-associated protein 1, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW67014.1};+++[H0YCI3_HUMAN|Unreviewed]SubName: Full=Transcriptional coactivator YAP1 {ECO:0000313|Ensembl:ENSP00000431626}; Flags: Fragment;+++[K0KVU2_HUMAN|Unreviewed]SubName: Full=Yes-associated protein isoform 9 {ECO:0000313|EMBL:CCI79622.1}; Flags: Fragment;+++[Q86T74_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451O0517 {ECO:0000313|EMBL:CAD89963.1}; Flags: Fragment;"]
[10417,"'SPON2'",1500,1322,1310,1377.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0001530///lipopolysaccharide binding+++GO:0003823///antigen binding","GO:0007411///axon guidance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0002448///mast cell mediated immunity+++GO:0008228///opsonization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0051607///defense response to virus+++GO:0032496///response to lipopolysaccharide+++GO:0007155///cell adhesion+++GO:0043152///induction of bacterial agglutination+++GO:0042742///defense response to bacterium+++GO:0050832///defense response to fungus+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0002376///immune system process","spondin 2","[SPON2_HUMAN|Reviewed]RecName: Full=Spondin-2; AltName: Full=Differentially expressed in cancerous and non-cancerous lung cells 1; Short=DIL-1; AltName: Full=Mindin; Flags: Precursor;+++[A0A1Y8ELY7_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421858}; Flags: Fragment;+++[D6RA41_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000423414}; Flags: Fragment;+++[D6RB12_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000424542}; Flags: Fragment;+++[D6RBY3_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000422516}; Flags: Fragment;+++[D6REX2_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421634}; Flags: Fragment;+++[D6RFY9_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421379}; Flags: Fragment;+++[D6RIH5_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000425871}; Flags: Fragment;"]
[10418,"'SPON1'",4,7,0,3.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region","GO:0005201///extracellular matrix structural constituent+++GO:0050693///LBD domain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:1902993///positive regulation of amyloid precursor protein catabolic process+++GO:0010954///positive regulation of protein processing+++GO:1902430///negative regulation of amyloid-beta formation+++GO:0032092///positive regulation of protein binding","spondin 1","[SPON1_HUMAN|Reviewed]RecName: Full=Spondin-1; AltName: Full=F-spondin; AltName: Full=Vascular smooth muscle cell growth-promoting factor; Flags: Precursor;+++[Q3ZCT3_HUMAN|Unreviewed]SubName: Full=SPON1 protein {ECO:0000313|EMBL:AAH41974.1}; Flags: Fragment;"]
[10419,"'PRMT5'",1151,1193,1112,1152,"04111///Cell cycle - yeast+++04011///MAPK signaling pathway - yeast+++03013///RNA transport",null,null,"R11220///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11218///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0035097///histone methyltransferase complex+++GO:0005737///cytoplasm+++GO:0034709///methylosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0008327///methyl-CpG binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0003714///transcription corepressor activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0044020///histone methyltransferase activity (H4-R3 specific)+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0070888///E-box binding+++GO:0005515///protein binding","GO:0006325///chromatin organization+++GO:1904992///positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0044030///regulation of DNA methylation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0042118///endothelial cell activation+++GO:0000387///spliceosomal snRNP assembly+++GO:0097421///liver regeneration+++GO:0043985///histone H4-R3 methylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0018216///peptidyl-arginine methylation+++GO:0008283///cell proliferation+++GO:0006479///protein methylation+++GO:0045596///negative regulation of cell differentiation+++GO:0048511///rhythmic process+++GO:0006353///DNA-templated transcription, termination+++GO:0032922///circadian regulation of gene expression+++GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0035246///peptidyl-arginine N-methylation+++GO:0032259///methylation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0034969///histone arginine methylation+++GO:0007088///regulation of mitotic nuclear division+++GO:0090161///Golgi ribbon formation","protein arginine methyltransferase 5","[ANM5_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 5; EC=2.1.1.320 {ECO:0000269|PubMed:21081503, ECO:0000269|PubMed:23071334}; AltName: Full=72 kDa ICln-binding protein; AltName: Full=Histone-arginine N-methyltransferase PRMT5; AltName: Full=Jak-binding protein 1; AltName: Full=Shk1 kinase-binding protein 1 homolog; Short=SKB1 homolog; Short=SKB1Hs; Contains: RecName: Full=Protein arginine N-methyltransferase 5, N-terminally processed;+++[B4DV00_HUMAN|Unreviewed]RecName: Full=Protein arginine N-methyltransferase 5 {ECO:0000256|PIRNR:PIRNR015894}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR015894};+++[C9JSX3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000409482}; Flags: Fragment;+++[G3V2F5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450633};+++[G3V2L6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450737}; Flags: Fragment;+++[G3V2X6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450919}; Flags: Fragment;+++[G3V3A3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451127};+++[G3V507_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452102};+++[G3V580_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452218}; Flags: Fragment;+++[G3V5L5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452411}; Flags: Fragment;+++[G3V5T6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452509}; Flags: Fragment;+++[H0YJ77_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450956}; Flags: Fragment;+++[H0YJD3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451245}; Flags: Fragment;+++[H0YJX6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452409}; Flags: Fragment;+++[H0YJY6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452501}; Flags: Fragment;+++[H7BZ44_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000387663}; Flags: Fragment;"]
[10420,"'TESK2'",34,30,36,33.3333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding","GO:0030036///actin cytoskeleton organization+++GO:0048041///focal adhesion assembly+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis","testis associated actin remodelling kinase 2","[TESK2_HUMAN|Reviewed]RecName: Full=Dual specificity testis-specific protein kinase 2; EC=2.7.12.1; AltName: Full=Testicular protein kinase 2;+++[B4DFN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58133, highly similar to Dual specificity testis-specific protein kinase 2 {ECO:0000313|EMBL:BAG57493.1};+++[D3DPZ7_HUMAN|Unreviewed]SubName: Full=Testis-specific kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAX06988.1};"]
[10421,"'CD2BP2'",786,877,689,784,"03015///mRNA surveillance pathway",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005682///U5 snRNP+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0010923///negative regulation of phosphatase activity+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0006397///mRNA processing","CD2 cytoplasmic tail binding protein 2","[CD2B2_HUMAN|Reviewed]RecName: Full=CD2 antigen cytoplasmic tail-binding protein 2; Short=CD2 cytoplasmic domain-binding protein 2; Short=CD2 tail-binding protein 2; AltName: Full=U5 snRNP 52K protein; Short=U5-52K;+++[A0A024QZC1_HUMAN|Unreviewed]SubName: Full=CD2 antigen (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW52261.1}; SubName: Full=CD2 binding protein 2 isoform 1 {ECO:0000313|EMBL:ALQ33976.1};+++[A0A0S2Z5J7_HUMAN|Unreviewed]SubName: Full=CD2 binding protein 2 isoform 2 {ECO:0000313|EMBL:ALQ33977.1}; Flags: Fragment;"]
[10422,"'UBAC1'",458,498,458,471.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0016567///protein ubiquitination","UBA domain containing 1","[UBAC1_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated domain-containing protein 1; Short=UBA domain-containing protein 1; AltName: Full=E3 ubiquitin-protein ligase subunit KPC2; AltName: Full=Glialblastoma cell differentiation-related protein 1; AltName: Full=Kip1 ubiquitination-promoting complex protein 2;+++[A0A024R8I2_HUMAN|Unreviewed]SubName: Full=Ubiquitin associated domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW88190.1};+++[A0A140VK64_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 64 {ECO:0000313|EMBL:AEE61201.1};"]
[10423,"'CDIPT'",1602,1480,1399,1493.66666666667,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00564///Glycerophospholipid metabolism+++00562///Inositol phosphate metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase   CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0019992///diacylglycerol binding+++GO:0043178///alcohol binding+++GO:0030246///carbohydrate binding+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046341///CDP-diacylglycerol metabolic process","CDP-diacylglycerol--inositol 3-phosphatidyltransferase","[CDIPT_HUMAN|Reviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase; EC=2.7.8.11; AltName: Full=Phosphatidylinositol synthase; Short=PI synthase; Short=PtdIns synthase;+++[A8K3L7_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KSW0_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KY94_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000455042}; SubName: Full=cDNA FLJ16129 fis, clone BRACE2039823, highly similar to CDP-diacylglycerol--inositol3-phosphatidyltransferase {ECO:0000313|EMBL:BAG54756.1};+++[H3BTJ7_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457207};+++[H3BUR9_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457766};"]
[10424,"'PGRMC2'",2472,1878,1841,2063.66666666667,{"$nulls":4},"GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0005496///steroid binding+++GO:0003707///steroid hormone receptor activity","GO:0043401///steroid hormone mediated signaling pathway","progesterone receptor membrane component 2","[PGRC2_HUMAN|Reviewed]RecName: Full=Membrane-associated progesterone receptor component 2; AltName: Full=Progesterone membrane-binding protein; AltName: Full=Steroid receptor protein DG6;+++[D3DNX8_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475242}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_a {ECO:0000313|EMBL:EAX05179.1};+++[U3KQ70_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475603}; Flags: Fragment;+++[U3KQM0_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000476010}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_c {ECO:0000313|EMBL:EAX05182.1};"]
[10425,"'ARIH2'",702.87,805.72,695.3,734.63,{"$nulls":4},"GO:0005634///nucleus+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0016740///transferase activity","GO:0016567///protein ubiquitination+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0007275///multicellular organism development+++GO:0070936///protein K48-linked ubiquitination+++GO:0048588///developmental cell growth+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination","ariadne RBR E3 ubiquitin protein ligase 2","[ARI2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase ARIH2; Short=ARI-2; Short=Protein ariadne-2 homolog; EC=2.3.2.31 {ECO:0000269|PubMed:16118314, ECO:0000269|PubMed:17646546, ECO:0000269|PubMed:19340006}; AltName: Full=RING-type E3 ubiquitin transferase ARIH2 {ECO:0000305}; AltName: Full=Triad1 protein {ECO:0000303|PubMed:10422847};+++[C9JAU2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000406063}; Flags: Fragment;+++[C9JBC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000397225}; Flags: Fragment;+++[C9JCL4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000404838}; Flags: Fragment;+++[C9JZ71_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000399788}; Flags: Fragment;+++[F8WCS4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000403845};+++[Q53ET9_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;+++[Q6IBL8_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};"]
[10426,"'TUBGCP3'",245,213,226,228,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005816///spindle pole body+++GO:0000923///equatorial microtubule organizing center+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000930///gamma-tubulin complex+++GO:0008275///gamma-tubulin small complex+++GO:0005827///polar microtubule+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005874///microtubule+++GO:0016020///membrane","GO:0005198///structural molecule activity+++GO:0051011///microtubule minus-end binding+++GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007020///microtubule nucleation+++GO:0051321///meiotic cell cycle+++GO:0090307///mitotic spindle assembly+++GO:0000226///microtubule cytoskeleton organization+++GO:0007338///single fertilization+++GO:0051415///microtubule nucleation by interphase microtubule organizing center+++GO:0031122///cytoplasmic microtubule organization","tubulin gamma complex associated protein 3","[GCP3_HUMAN|Reviewed]RecName: Full=Gamma-tubulin complex component 3; Short=GCP-3; Short=hGCP3; AltName: Full=Gamma-ring complex protein 104 kDa; Short=h104p; Short=hGrip104; AltName: Full=Spindle pole body protein Spc98 homolog; Short=hSpc98;+++[A0A087WU06_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};+++[A0A087WZV5_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX56_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX63_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[B4DYP7_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};"]
[10427,"'SEC24B'",860,784,823,822.333333333333,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0000139///Golgi membrane+++GO:0030127///COPII vesicle coat+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1901301///regulation of cargo loading into COPII-coated vesicle+++GO:0001843///neural tube closure+++GO:0015031///protein transport+++GO:0072358///cardiovascular system development+++GO:0002093///auditory receptor cell morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060425///lung morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006886///intracellular protein transport+++GO:0061156///pulmonary artery morphogenesis+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0021747///cochlear nucleus development+++GO:0035909///aorta morphogenesis+++GO:0016192///vesicle-mediated transport+++GO:0090178///regulation of establishment of planar polarity involved in neural tube closure+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060463///lung lobe morphogenesis","SEC24 homolog B, COPII coat complex component","[SC24B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24B {ECO:0000305}; AltName: Full=SEC24-related protein B;+++[B4DTM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61391, highly similar to Protein transport protein Sec24B {ECO:0000313|EMBL:BAG62038.1};"]
[10428,"'CFDP1'",672,713,653,679.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0005575///cellular_component+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore","GO:0003674///molecular_function","GO:0007275///multicellular organism development+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:0008150///biological_process+++GO:0008360///regulation of cell shape+++GO:0007155///cell adhesion+++GO:0042127///regulation of cell proliferation","craniofacial development protein 1","[CFDP1_HUMAN|Reviewed]RecName: Full=Craniofacial development protein 1; AltName: Full=Bucentaur;+++[A0A087WXQ2_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000481200}; Flags: Fragment;+++[A0A0H5APX3_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91204.1};+++[A0A0H5AUJ9_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91203.1};+++[A0A0H5B9V7_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91205.1};+++[H3BQ17_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000455564}; Flags: Fragment;+++[J3KT89_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000462862}; Flags: Fragment;"]
[1043,"'CD52'",4,1,1,2,{"$nulls":4},"GO:0031225///anchored component of membrane+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0016020///membrane+++GO:0097225///sperm midpiece+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane",null,"GO:0045730///respiratory burst+++GO:0007204///positive regulation of cytosolic calcium ion concentration","CD52 molecule","[CD52_HUMAN|Reviewed]RecName: Full=CAMPATH-1 antigen; AltName: Full=CDw52; AltName: Full=Cambridge pathology 1 antigen; AltName: Full=Epididymal secretory protein E5; AltName: Full=Human epididymis-specific protein 5; Short=He5; AltName: CD_antigen=CD52; Flags: Precursor;+++[Q6IBD0_HUMAN|Unreviewed]SubName: Full=CD52 antigen (CAMPATH-1 antigen) {ECO:0000313|EMBL:EAX07822.1}; SubName: Full=CDW52 antigen (CAMPATH-1 antigen) {ECO:0000313|EMBL:AAP35780.1}; SubName: Full=CDW52 protein {ECO:0000313|EMBL:CAG33155.1};+++[Q9UJ81_HUMAN|Unreviewed]SubName: Full=CD52 protein {ECO:0000313|EMBL:CAB51285.1}; Flags: Fragment;+++[V9HWN9_HUMAN|Unreviewed]SubName: Full=CD52 antigen {ECO:0000313|EMBL:AJC19276.1}; SubName: Full=Epididymis secretory sperm binding protein Li 171mP {ECO:0000313|EMBL:ACS44650.1};"]
[10430,"'TMEM147'",1419,1300,1317,1345.33333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0032991///protein-containing complex","GO:0005515///protein binding",null,"transmembrane protein 147","[TM147_HUMAN|Reviewed]RecName: Full=Transmembrane protein 147; AltName: Full=Protein NIFIE 14;+++[A8MU21_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000376041};+++[K7ELX3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000466262};"]
[10432,"'RBM14'",927.72,1060.02,936,974.58,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0003676///nucleic acid binding+++GO:0030674///protein binding, bridging+++GO:0003723///RNA binding+++GO:0003712///transcription coregulator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0002218///activation of innate immune response+++GO:0006281///DNA repair+++GO:0045087///innate immune response+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0006310///DNA recombination+++GO:0016575///histone deacetylation+++GO:0098534///centriole assembly+++GO:0046600///negative regulation of centriole replication+++GO:0002376///immune system process+++GO:0009725///response to hormone+++GO:0042921///glucocorticoid receptor signaling pathway","RNA binding motif protein 14","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0S2Z4Z0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 1 {ECO:0000313|EMBL:ALQ33978.1}; Flags: Fragment;+++[A0A0S2Z567_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 2 {ECO:0000313|EMBL:ALQ33979.1};+++[A0A0S2Z5V2_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 3 {ECO:0000313|EMBL:ALQ33980.1};+++[B8ZZ74_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000386518};+++[F8WDX3_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000414650};"]
[10434,"'LYPLA1'",490,411,452,451,"05231///Choline metabolism in cancer+++00564///Glycerophospholipid metabolism",null,null,"R02746///1-Acyl-sn-glycero-3-phosphocholine acylhydrolase   1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid+++R03416///1-Acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase   1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine","GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0016298///lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0008474///palmitoyl-(protein) hydrolase activity","GO:0042997///negative regulation of Golgi to plasma membrane protein transport+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0006631///fatty acid metabolic process+++GO:0002084///protein depalmitoylation+++GO:0006629///lipid metabolic process","lysophospholipase I","[LYPA1_HUMAN|Reviewed]RecName: Full=Acyl-protein thioesterase 1; Short=APT-1; Short=hAPT1; EC=3.1.2.-; AltName: Full=Lysophospholipase 1; AltName: Full=Lysophospholipase I; Short=LPL-I; Short=LysoPLA I;+++[A0A087X1K9_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000484280};+++[B4DP64_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000482430}; SubName: Full=cDNA FLJ52008, highly similar to Acyl-protein thioesterase 1 {ECO:0000313|EMBL:BAG60476.1};+++[E5RFT6_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000427967};+++[E5RGR0_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428729}; Flags: Fragment;+++[E5RI35_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000430791}; Flags: Fragment;+++[E5RJ48_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428306}; Flags: Fragment;+++[Q6IAQ1_HUMAN|Unreviewed]SubName: Full=LYPLA1 protein {ECO:0000313|EMBL:CAG33384.1}; SubName: Full=Lysophospholipase I, isoform CRA_a {ECO:0000313|EMBL:EAW86742.1}; SubName: Full=cDNA FLJ78542, highly similar to Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAF82089.1}; SubName: Full=cDNA, FLJ94339, Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAG36480.1};"]
[10435,"'CDC42EP2'",609,498,572,559.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0045335///phagocytic vesicle+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017049///GTP-Rho binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0001515///opioid peptide activity","GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity+++GO:0007266///Rho protein signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0008360///regulation of cell shape+++GO:0010469///regulation of signaling receptor activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007015///actin filament organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031274///positive regulation of pseudopodium assembly","CDC42 effector protein 2","[BORG1_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 2; AltName: Full=Binder of Rho GTPases 1;"]
[10436,"'EMG1'",188,173,203,188,"03008///Ribosome biogenesis in eukaryotes","H00616///Bowen-Conradi syndrome (BCS)",null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0070037///rRNA (pseudouridine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0019843///rRNA binding+++GO:0016740///transferase activity","GO:0042274///ribosomal small subunit biogenesis+++GO:0042254///ribosome biogenesis+++GO:0001824///blastocyst development+++GO:0017126///nucleologenesis+++GO:0032259///methylation+++GO:0070475///rRNA base methylation+++GO:0006364///rRNA processing","EMG1, N1-specific pseudouridine methyltransferase","[NEP1_HUMAN|Reviewed]RecName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000305|PubMed:20047967}; EC=2.1.1.- {ECO:0000269|PubMed:20047967}; AltName: Full=18S rRNA (pseudouridine(1248)-N1)-methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=18S rRNA Psi1248 methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=Nucleolar protein EMG1 homolog {ECO:0000250|UniProtKB:Q06287}; AltName: Full=Protein C2f {ECO:0000303|PubMed:9074930}; AltName: Full=Ribosome biogenesis protein NEP1 {ECO:0000303|PubMed:20047967};+++[A0A087WVM7_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000479546}; Flags: Fragment;+++[A0A087WWQ2_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000480420}; Flags: Fragment;+++[A0A0U3B3H7_HUMAN|Unreviewed]SubName: Full=EMG1 N1-specific pseudouridine methyl transferase {ECO:0000313|EMBL:ALT07792.1}; Flags: Fragment;+++[B4DP65_HUMAN|Unreviewed]SubName: Full=EMG1 nucleolar protein homolog (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW88694.1}; SubName: Full=cDNA FLJ56921, highly similar to Probable ribosome biogenesis protein NEP1 {ECO:0000313|EMBL:BAG60477.1};+++[V9GYP5_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000476966}; Flags: Fragment;"]
[10437,"'IFI30'",1090,1219,1113,1140.66666666667,"04612///Antigen processing and presentation",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030054///cell junction+++GO:0043202///lysosomal lumen+++GO:0005764///lysosome+++GO:0005576///extracellular region+++GO:0005829///cytosol","GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0016667///oxidoreductase activity, acting on a sulfur group of donors","GO:0055114///oxidation-reduction process+++GO:0002376///immune system process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I","IFI30, lysosomal thiol reductase","[GILT_HUMAN|Reviewed]RecName: Full=Gamma-interferon-inducible lysosomal thiol reductase; EC=1.8.-.- {ECO:0000269|PubMed:10639150, ECO:0000269|PubMed:10852914}; AltName: Full=Gamma-interferon-inducible protein IP-30; AltName: Full=Legumaturain; Flags: Precursor;+++[A0A024R7N7_HUMAN|Unreviewed]SubName: Full=Interferon, gamma-inducible protein 30, isoform CRA_b {ECO:0000313|EMBL:EAW84665.1};+++[M0QZG3_HUMAN|Unreviewed]SubName: Full=Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000313|Ensembl:ENSP00000470527}; Flags: Fragment;+++[Q96P99_HUMAN|Unreviewed]SubName: Full=Interferon gamma-inducible protein 30 {ECO:0000313|EMBL:AAL02170.1}; Flags: Fragment;"]
[10438,"'C1D'",143,139,167,149.666666666667,"03018///RNA degradation",{"$nulls":3},"GO:0017053///transcriptional repressor complex+++GO:0005769///early endosome+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0098797///plasma membrane protein complex+++GO:0005886///plasma membrane+++GO:0030666///endocytic vesicle membrane+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005905///clathrin-coated pit+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0030136///clathrin-coated vesicle+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex","GO:0044877///protein-containing complex binding+++GO:0003677///DNA binding+++GO:0016964///alpha-2 macroglobulin receptor activity+++GO:0002020///protease binding+++GO:0042954///lipoprotein transporter activity+++GO:0032050///clathrin heavy chain binding+++GO:0038023///signaling receptor activity+++GO:0003714///transcription corepressor activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0030226///apolipoprotein receptor activity+++GO:0005509///calcium ion binding+++GO:0070325///lipoprotein particle receptor binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0034185///apolipoprotein binding","GO:0042157///lipoprotein metabolic process+++GO:0006915///apoptotic process+++GO:0006364///rRNA processing+++GO:0032092///positive regulation of protein binding+++GO:0051222///positive regulation of protein transport+++GO:0008283///cell proliferation+++GO:0032374///regulation of cholesterol transport+++GO:0010942///positive regulation of cell death+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0042953///lipoprotein transport+++GO:0006897///endocytosis+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0010875///positive regulation of cholesterol efflux+++GO:0002265///astrocyte activation involved in immune response+++GO:0006629///lipid metabolic process+++GO:0000460///maturation of 5.8S rRNA+++GO:0035909///aorta morphogenesis+++GO:0043277///apoptotic cell clearance+++GO:0045732///positive regulation of protein catabolic process+++GO:0051246///regulation of protein metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010977///negative regulation of neuron projection development+++GO:0031623///receptor internalization+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905167///positive regulation of lysosomal protein catabolic process+++GO:0032429///regulation of phospholipase A2 activity+++GO:1904646///cellular response to amyloid-beta+++GO:0006898///receptor-mediated endocytosis+++GO:0001523///retinoid metabolic process+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0021987///cerebral cortex development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0045056///transcytosis+++GO:0097242///amyloid-beta clearance+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0006909///phagocytosis+++GO:0032370///positive regulation of lipid transport+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0045807///positive regulation of endocytosis","C1D nuclear receptor corepressor","[C1D_HUMAN|Reviewed]RecName: Full=Nuclear nucleic acid-binding protein C1D; Short=hC1D;+++[H0YJ88_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451012}; Flags: Fragment;+++[H0YJI8_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451622}; Flags: Fragment;+++[J3KPZ4_HUMAN|Unreviewed]SubName: Full=Nuclear nucleic acid-binding protein C1D {ECO:0000313|Ensembl:ENSP00000384304};+++[L0R6J6_HUMAN|Unreviewed]SubName: Full=Alternative protein LRP1 {ECO:0000313|EMBL:CCO13765.1};+++[Q6PJ72_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH21204.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451737};+++[Q7Z7K9_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH52593.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451449};"]
[10439,"'OLFM1'",1,4,1,2,{"$nulls":4},"GO:0045202///synapse+++GO:0043204///perikaryon+++GO:0005615///extracellular space+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0044295///axonal growth cone+++GO:0005623///cell+++GO:0005576///extracellular region","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0030516///regulation of axon extension+++GO:0023041///neuronal signal transduction+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0003190///atrioventricular valve formation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression","olfactomedin 1","[NOE1_HUMAN|Reviewed]RecName: Full=Noelin; AltName: Full=Neuronal olfactomedin-related ER localized protein; AltName: Full=Olfactomedin-1; Flags: Precursor;+++[F5GZQ2_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000444296}; Flags: Fragment;+++[F5H810_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000443806}; Flags: Fragment;+++[F8W870_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000340318}; Flags: Fragment;+++[H0YFB9_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000437906}; Flags: Fragment;+++[Q5VZL8_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360866};+++[Q6IMJ6_HUMAN|Unreviewed]SubName: Full=NOELIN1_V5 {ECO:0000313|EMBL:DAA01549.1}; SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360864};+++[Q6IMJ7_HUMAN|Unreviewed]SubName: Full=NOELIN1_V4 {ECO:0000313|EMBL:DAA01548.1}; SubName: Full=Olfactomedin 1, isoform CRA_d {ECO:0000313|EMBL:EAW88145.1};+++[Q6IMJ8_HUMAN|Unreviewed]SubName: Full=NOELIN1_V1 {ECO:0000313|EMBL:DAA01545.1}; SubName: Full=Olfactomedin 1, isoform CRA_c {ECO:0000313|EMBL:EAW88144.1};+++[Q96BL8_HUMAN|Unreviewed]SubName: Full=OLFM1 protein {ECO:0000313|EMBL:AAH15437.2}; Flags: Fragment;+++[Q9BWJ9_HUMAN|Unreviewed]SubName: Full=Olfactomedin 1 {ECO:0000313|EMBL:AAH00189.1}; SubName: Full=Olfactomedin 1, isoform CRA_b {ECO:0000313|EMBL:EAW88143.1};"]
[1044,"'CDX1'",18,10,11,13,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008327///methyl-CpG binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding","GO:0009887///animal organ morphogenesis+++GO:0014807///regulation of somitogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060349///bone morphogenesis+++GO:0030154///cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009952///anterior/posterior pattern specification+++GO:0007389///pattern specification process+++GO:0007275///multicellular organism development+++GO:0045944///positive regulation of transcription by RNA polymerase II","caudal type homeobox 1","[CDX1_HUMAN|Reviewed]RecName: Full=Homeobox protein CDX-1; AltName: Full=Caudal-type homeobox protein 1;+++[A0A087WTJ6_HUMAN|Unreviewed]SubName: Full=Homeobox protein CDX-1 {ECO:0000313|Ensembl:ENSP00000477928};+++[Q14DX0_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96249.1};+++[Q4VAU3_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96252.2};+++[Q4VAU5_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96250.1};"]
[10440,"'TIMM17A'",340,246,268,284.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex","GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0010954///positive regulation of protein processing+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0071806///protein transmembrane transport+++GO:0006886///intracellular protein transport+++GO:0006626///protein targeting to mitochondrion","translocase of inner mitochondrial membrane 17A","[TI17A_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-A; AltName: Full=Inner membrane preprotein translocase Tim17a;+++[A0A024R9A5_HUMAN|Unreviewed]SubName: Full=Translocase of inner mitochondrial membrane 17 homolog A (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW91385.1};+++[A0PJ74_HUMAN|Unreviewed]SubName: Full=TIMM17A protein {ECO:0000313|EMBL:AAH16817.1}; Flags: Fragment;+++[Q7RU05_HUMAN|Unreviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM17 {ECO:0000256|RuleBase:RU364008};"]
[10443,"'N4BP2L2'",359,360,335,351.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex","GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1902037///negative regulation of hematopoietic stem cell differentiation+++GO:1902035///positive regulation of hematopoietic stem cell proliferation","NEDD4 binding protein 2 like 2","[N42L2_HUMAN|Reviewed]RecName: Full=NEDD4-binding protein 2-like 2; AltName: Full=Phosphonoformate immuno-associated protein 5;+++[A0A024RDV2_HUMAN|Unreviewed]SubName: Full=HCG32190, isoform CRA_b {ECO:0000313|EMBL:EAX08515.1};+++[B4DPY1_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000350104}; SubName: Full=cDNA FLJ55497 {ECO:0000313|EMBL:BAG60743.1};+++[D6R968_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000423362}; Flags: Fragment;+++[Q96KV2_HUMAN|Unreviewed]SubName: Full=92M18.3 (Novel protein) {ECO:0000313|EMBL:CAC94790.1};+++[Q9Y3H6_HUMAN|Unreviewed]SubName: Full=HCG33128, isoform CRA_a {ECO:0000313|EMBL:EAX08509.1};"]
[10444,"'ZER1'",2618,2566,2310,2498,{"$nulls":4},"GO:0031462///Cul2-RING ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:0016567///protein ubiquitination","zyg-11 related cell cycle regulator","[ZER1_HUMAN|Reviewed]RecName: Full=Protein zer-1 homolog; AltName: Full=Hzyg; AltName: Full=Zyg-11 homolog B-like protein; AltName: Full=Zyg11b-like protein;+++[A0A024R8B0_HUMAN|Unreviewed]SubName: Full=Zyg-11 homolog B (C. elegans)-like, isoform CRA_b {ECO:0000313|EMBL:EAW87831.1};+++[Q05BR7_HUMAN|Unreviewed]SubName: Full=ZER1 protein {ECO:0000313|EMBL:AAH33884.1}; Flags: Fragment;+++[X6RC68_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000389271}; Flags: Fragment;+++[X6RD87_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000393051}; Flags: Fragment;"]
[10445,"'MCRS1'",893,975,847,905,"05168///Herpes simplex infection",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0044545///NSL complex+++GO:0043204///perikaryon+++GO:0030425///dendrite+++GO:0000123///histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0031011///Ino80 complex+++GO:0005634///nucleus+++GO:0071339///MLL1 complex+++GO:0005730///nucleolus+++GO:0005844///polysome","GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0034046///poly(G) binding+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)+++GO:0010521///telomerase inhibitor activity+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0008266///poly(U) RNA binding+++GO:0005515///protein binding+++GO:0002151///G-quadruplex RNA binding","GO:0006310///DNA recombination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006464///cellular protein modification process+++GO:0043982///histone H4-K8 acetylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043981///histone H4-K5 acetylation+++GO:0051974///negative regulation of telomerase activity+++GO:0016579///protein deubiquitination+++GO:0043984///histone H4-K16 acetylation+++GO:0006281///DNA repair+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:0006325///chromatin organization+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening","microspherule protein 1","[MCRS1_HUMAN|Reviewed]RecName: Full=Microspherule protein 1; AltName: Full=58 kDa microspherule protein; AltName: Full=Cell cycle-regulated factor p78; AltName: Full=INO80 complex subunit J; AltName: Full=MCRS2;+++[A0A024R134_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1, isoform CRA_d {ECO:0000313|EMBL:EAW58079.1};+++[F8VP44_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000450352}; Flags: Fragment;+++[F8VVA6_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000449343}; Flags: Fragment;+++[F8VZC2_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447739};+++[F8W0I9_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447592}; Flags: Fragment;+++[F8W126_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447514}; Flags: Fragment;+++[H0YI67_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448700}; Flags: Fragment;+++[H0YIA0_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448947}; Flags: Fragment;+++[L8E8H6_HUMAN|Unreviewed]SubName: Full=Alternative protein MCRS1 {ECO:0000313|EMBL:CCQ43031.1};"]
[10446,"'LRRN2'",3953,5205,4115,4424.33333333333,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005615///extracellular space","GO:0038023///signaling receptor activity","GO:0007165///signal transduction+++GO:0007155///cell adhesion","leucine rich repeat neuronal 2","[LRRN2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat neuronal protein 2; AltName: Full=Glioma amplified on chromosome 1 protein; AltName: Full=Leucine-rich repeat neuronal protein 5; Flags: Precursor;+++[A0A024R993_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat neuronal 5, isoform CRA_a {ECO:0000313|EMBL:EAW91521.1};"]
[10447,"'FAM3C'",552,387,434,457.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031089///platelet dense granule lumen+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle","GO:0005125///cytokine activity+++GO:0005515///protein binding","GO:0010469///regulation of signaling receptor activity+++GO:0008150///biological_process+++GO:0045721///negative regulation of gluconeogenesis+++GO:0007275///multicellular organism development+++GO:0002576///platelet degranulation","family with sequence similarity 3 member C","[FAM3C_HUMAN|Reviewed]RecName: Full=Protein FAM3C; AltName: Full=Interleukin-like EMT inducer; Flags: Precursor;+++[C9JMN4_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000408636}; Flags: Fragment;+++[C9JP35_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000414940}; Flags: Fragment;"]
[10449,"'ACAA2'",850,814,705,789.666666666667,"01212///Fatty acid metabolism+++01100///Metabolic pathways+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++00280///Valine, leucine and isoleucine degradation+++01130///Biosynthesis of antibiotics+++00062///Fatty acid elongation",null,"M00087///beta-Oxidation+++M00085///Fatty acid biosynthesis, elongation, mitochondria","R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase   Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase   Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase   Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00391///Acyl-CoA:acetyl-CoA C-acyltransferase   Acyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoacyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase   Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase   Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase   Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA   Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA","GO:0005759///mitochondrial matrix+++GO:0016459///myosin complex+++GO:0005739///mitochondrion","GO:0003824///catalytic activity+++GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0003774///motor activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding","GO:0006629///lipid metabolic process+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0071456///cellular response to hypoxia+++GO:0006635///fatty acid beta-oxidation+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","acetyl-CoA acyltransferase 2","[THIM_HUMAN|Reviewed]RecName: Full=3-ketoacyl-CoA thiolase, mitochondrial; EC=2.3.1.16; AltName: Full=Acetyl-CoA acyltransferase; AltName: Full=Beta-ketothiolase; AltName: Full=Mitochondrial 3-oxoacyl-CoA thiolase; AltName: Full=T1;+++[A0A024R269_HUMAN|Unreviewed]SubName: Full=Acetyl-Coenzyme A acyltransferase 2 (Mitochondrial 3-oxoacyl-Coenzyme A thiolase), isoform CRA_d {ECO:0000313|EMBL:EAW62956.1};+++[A0A0B4J2A4_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466015};+++[B3KNP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30111 fis, clone BNGH42000360, highly similar to 3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|EMBL:BAG51410.1};+++[K7EJ68_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465045}; Flags: Fragment;+++[K7EJB1_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465095}; Flags: Fragment;+++[K7EME0_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466466};+++[K7ER88_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000468157}; Flags: Fragment;"]
[10450,"'PPIE'",377,371,361,369.666666666667,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000974///Prp19 complex+++GO:0034774///secretory granule lumen+++GO:0071013///catalytic step 2 spliceosome+++GO:0005576///extracellular region+++GO:0005681///spliceosomal complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0051082///unfolded protein binding+++GO:0016853///isomerase activity+++GO:0003676///nucleic acid binding+++GO:0016018///cyclosporin A binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008143///poly(A) binding","GO:0006457///protein folding+++GO:0043312///neutrophil degranulation+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0045070///positive regulation of viral genome replication+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0006355///regulation of transcription, DNA-templated","peptidylprolyl isomerase E","[PPIE_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase E; Short=PPIase E; EC=5.2.1.8 {ECO:0000269|PubMed:18258190, ECO:0000269|PubMed:20541251, ECO:0000269|PubMed:20677832, ECO:0000269|PubMed:8977107}; AltName: Full=Cyclophilin E; AltName: Full=Cyclophilin-33 {ECO:0000303|PubMed:8977107}; AltName: Full=Rotamase E;+++[B3KSZ1_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PEQ6_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PIB0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000436689}; Flags: Fragment;+++[E9PK21_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000431714};+++[E9PKY5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[E9PMH0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434989};+++[H0YCV4_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000432396}; Flags: Fragment;+++[H0YE31_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434888}; Flags: Fragment;"]
[10451,"'VAV3'",33,44,63,46.6666666666667,"04670///Leukocyte transendothelial migration+++04664///Fc epsilon RI signaling pathway+++04662///B cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04666///Fc gamma R-mediated phagocytosis+++04062///Chemokine signaling pathway+++04660///T cell receptor signaling pathway+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005096///GTPase activator activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0001525///angiogenesis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0050853///B cell receptor signaling pathway+++GO:0030032///lamellipodium assembly+++GO:0030031///cell projection assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0016477///cell migration+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0043087///regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008361///regulation of cell size+++GO:0009967///positive regulation of signal transduction+++GO:0048013///ephrin receptor signaling pathway+++GO:0006906///vesicle fusion+++GO:0042493///response to drug+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030593///neutrophil chemotaxis+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0030168///platelet activation+++GO:0030890///positive regulation of B cell proliferation+++GO:0007229///integrin-mediated signaling pathway+++GO:0045785///positive regulation of cell adhesion","vav guanine nucleotide exchange factor 3","[VAV3_HUMAN|Reviewed]RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3;+++[A0A2X0U2Q1_HUMAN|Unreviewed]SubName: Full=VAV3 {ECO:0000313|EMBL:SPT35811.1}; Flags: Fragment;+++[E9PMJ5_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000434944};+++[H0YCG7_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000431544}; Flags: Fragment;+++[H0YDG2_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000433559}; Flags: Fragment;"]
[10452,"'TOMM40'",1250,1309,1234,1264.33333333333,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0046930///pore complex+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0005829///cytosol","GO:0008320///protein transmembrane transporter activity+++GO:0015288///porin activity+++GO:0005515///protein binding","GO:0006626///protein targeting to mitochondrion+++GO:0055085///transmembrane transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0006811///ion transport","translocase of outer mitochondrial membrane 40","[TOM40_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM40 homolog; AltName: Full=Protein Haymaker; AltName: Full=Translocase of outer membrane 40 kDa subunit homolog; AltName: Full=p38.5;+++[K7EJ57_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465032}; Flags: Fragment;+++[K7EKG4_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465608}; Flags: Fragment;+++[K7EKG6_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465611}; Flags: Fragment;"]
[10454,"'TAB1'",945,997,894,945.333333333333,"05145///Toxoplasmosis+++05169///Epstein-Barr virus infection+++05168///Herpes simplex infection+++05140///Leishmaniasis+++04620///Toll-like receptor signaling pathway+++04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway+++04380///Osteoclast differentiation",null,"M00686///Toll-like receptor signaling",null,"GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016607///nuclear speck","GO:0003824///catalytic activity+++GO:0008047///enzyme activator activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0019209///kinase activator activity+++GO:0016301///kinase activity+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:0005515///protein binding","GO:0030324///lung development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0001701///in utero embryonic development+++GO:0000185///activation of MAPKKK activity+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0035904///aorta development+++GO:0003279///cardiac septum development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006470///protein dephosphorylation+++GO:0000187///activation of MAPK activity+++GO:0060976///coronary vasculature development+++GO:0016579///protein deubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0003007///heart morphogenesis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0007254///JNK cascade","TGF-beta activated kinase 1 (MAP3K7) binding protein 1","[TAB1_HUMAN|Reviewed]RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; AltName: Full=TGF-beta-activated kinase 1-binding protein 1; Short=TAK1-binding protein 1;+++[A8K6K3_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 7 interacting protein 1, isoform CRA_f {ECO:0000313|EMBL:EAW60330.1}; SubName: Full=cDNA FLJ78598, highly similar to Homo sapiens mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (MAP3K7IP1), transcript variant alpha, mRNA {ECO:0000313|EMBL:BAF84357.1}; SubName: Full=cDNA, FLJ92811, Homo sapiens mitogen-activated protein kinase kinase kinase 7interacting protein 1 (MAP3K7IP1), mRNA {ECO:0000313|EMBL:BAG35363.1};"]
[10455,"'ECI2'",361,376,331,356,"04146///Peroxisome+++00071///Fatty acid degradation",null,null,"R04756///cis,cis-3,6-Dodecadienoyl-CoA delta3-cis-delta2-trans-isomerase   cis,cis-3,6-Dodecadienoyl-CoA <=> trans,cis-Lauro-2,6-dienoyl-CoA","GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005782///peroxisomal matrix","GO:0000062///fatty-acyl-CoA binding+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds+++GO:0003824///catalytic activity+++GO:0005102///signaling receptor binding+++GO:0016853///isomerase activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity","GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0006635///fatty acid beta-oxidation","enoyl-CoA delta isomerase 2","[ECI2_HUMAN|Reviewed]RecName: Full=Enoyl-CoA delta isomerase 2, mitochondrial; EC=5.3.3.8; AltName: Full=DRS-1; AltName: Full=Delta(3),delta(2)-enoyl-CoA isomerase; Short=D3,D2-enoyl-CoA isomerase; AltName: Full=Diazepam-binding inhibitor-related protein 1; Short=DBI-related protein 1; AltName: Full=Dodecenoyl-CoA isomerase; AltName: Full=Hepatocellular carcinoma-associated antigen 88; AltName: Full=Peroxisomal 3,2-trans-enoyl-CoA isomerase; Short=pECI; AltName: Full=Renal carcinoma antigen NY-REN-1; Flags: Precursor;+++[A0A024QZU5_HUMAN|Unreviewed]SubName: Full=Peroxisomal D3,D2-enoyl-CoA isomerase, isoform CRA_a {ECO:0000313|EMBL:EAW55162.1};+++[A0A0C4DGA2_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000420309}; SubName: Full=Testicular secretory protein Li 33 {ECO:0000313|EMBL:AEE61170.1};+++[C9JB63_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417459}; Flags: Fragment;+++[F1LLU7_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417803};+++[F8W6J1_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000369463};+++[F8WAW4_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417170};+++[Q6IBN4_HUMAN|Unreviewed]SubName: Full=PECI protein {ECO:0000313|EMBL:CAG33049.1};"]
[10456,"'HAX1'",627,586,524,579,null,"H00100///Neutropenic disorders",null,null,"GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0000932///P-body+++GO:0016529///sarcoplasmic reticulum+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030027///lamellipodium","GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0019966///interleukin-1 binding","GO:0030854///positive regulation of granulocyte differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0042981///regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling","HCLS1 associated protein X-1","[HAX1_HUMAN|Reviewed]RecName: Full=HCLS1-associated protein X-1; AltName: Full=HS1-associating protein X-1; Short=HAX-1; AltName: Full=HS1-binding protein 1; Short=HSP1BP-1;+++[A0A0S2Z519_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 5 {ECO:0000313|EMBL:ALQ33983.1};+++[A0A0S2Z565_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 3 {ECO:0000313|EMBL:ALQ33982.1}; Flags: Fragment;+++[A0A0S2Z591_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 1 {ECO:0000313|EMBL:ALQ33981.1}; Flags: Fragment;+++[E9PIQ7_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000433951};+++[Q5VYD6_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000394920}; Flags: Fragment;"]
[10457,"'GPNMB'",39239,38619,34283,37380.3333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0005887///integral component of plasma membrane","GO:0005178///integrin binding+++GO:0045545///syndecan binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042056///chemoattractant activity+++GO:0048018///receptor ligand activity+++GO:0008201///heparin binding+++GO:0031710///neuromedin B receptor binding","GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0030282///bone mineralization+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0050918///positive chemotaxis+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0050482///arachidonic acid secretion+++GO:0001818///negative regulation of cytokine production+++GO:0045765///regulation of angiogenesis+++GO:0050868///negative regulation of T cell activation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0046888///negative regulation of hormone secretion+++GO:0034103///regulation of tissue remodeling+++GO:0008284///positive regulation of cell proliferation+++GO:0010469///regulation of signaling receptor activity+++GO:0042130///negative regulation of T cell proliferation+++GO:0042593///glucose homeostasis+++GO:0046887///positive regulation of hormone secretion+++GO:0008285///negative regulation of cell proliferation+++GO:0001649///osteoblast differentiation+++GO:0030335///positive regulation of cell migration+++GO:1901215///negative regulation of neuron death+++GO:0007267///cell-cell signaling+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007165///signal transduction","glycoprotein nmb","[GPNMB_HUMAN|Reviewed]RecName: Full=Transmembrane glycoprotein NMB; AltName: Full=Hematopoietic growth factor inducible neurokinin-1 type {ECO:0000303|PubMed:12609765}; Flags: Precursor;+++[A0A024RA55_HUMAN|Unreviewed]SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_b {ECO:0000313|EMBL:EAW93784.1};+++[Q8IXJ5_HUMAN|Unreviewed]SubName: Full=Glycoprotein nmb-like protein {ECO:0000313|EMBL:CAD43718.1};+++[Q96F58_HUMAN|Unreviewed]SubName: Full=GPNMB protein {ECO:0000313|EMBL:AAH11595.1}; SubName: Full=Glycoprotein (Transmembrane) nmb {ECO:0000313|EMBL:AAP35737.1}; SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_a {ECO:0000313|EMBL:EAW93781.1}; SubName: Full=Transmembrane glycoprotein NMB {ECO:0000313|Ensembl:ENSP00000386476};"]
[10458,"'BAIAP2'",3304,3921,3467,3564,"04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0099524///postsynaptic cytosol+++GO:0061846///dendritic spine cytoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043197///dendritic spine+++GO:0043025///neuronal cell body+++GO:0097060///synaptic membrane+++GO:0015629///actin cytoskeleton+++GO:0044306///neuron projection terminus+++GO:0042995///cell projection+++GO:0043198///dendritic shaft+++GO:0030175///filopodium+++GO:0001726///ruffle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0098793///presynapse+++GO:0099092///postsynaptic density, intracellular component+++GO:0099523///presynaptic cytosol+++GO:0061845///neuron projection branch point+++GO:0005791///rough endoplasmic reticulum+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0060076///excitatory synapse+++GO:0098794///postsynapse+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0014069///postsynaptic density","GO:0001221///transcription cofactor binding+++GO:0030165///PDZ domain binding+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0070064///proline-rich region binding+++GO:0042802///identical protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0097110///scaffold protein binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding","GO:0010976///positive regulation of neuron projection development+++GO:1905232///cellular response to L-glutamate+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0099564///modification of synaptic structure, modulating synaptic transmission+++GO:0008286///insulin receptor signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0050804///modulation of chemical synaptic transmission+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:0007009///plasma membrane organization+++GO:0007420///brain development+++GO:0030182///neuron differentiation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0016358///dendrite development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0048167///regulation of synaptic plasticity+++GO:0008360///regulation of cell shape+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0051764///actin crosslink formation+++GO:0035418///protein localization to synapse+++GO:0007409///axonogenesis+++GO:0051017///actin filament bundle assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0009617///response to bacterium","BAI1 associated protein 2","[BAIP2_HUMAN|Reviewed]RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2; Short=BAI-associated protein 2; Short=BAI1-associated protein 2; Short=Protein BAP2; AltName: Full=Fas ligand-associated factor 3; Short=FLAF3; AltName: Full=Insulin receptor substrate p53/p58; Short=IRS-58; Short=IRSp53/58; AltName: Full=Insulin receptor substrate protein of 53 kDa; Short=IRSp53; Short=Insulin receptor substrate p53;+++[B4DWA1_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000391837}; SubName: Full=cDNA FLJ55181, highly similar to Brain-specific angiogenesis inhibitor1-associated protein 2 {ECO:0000313|EMBL:BAG62963.1};+++[I3L0M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458202}; Flags: Fragment;+++[I3L0Y9_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458440}; Flags: Fragment;+++[I3L113_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458494}; Flags: Fragment;+++[I3L125_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458522}; Flags: Fragment;+++[I3L1C8_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458735}; Flags: Fragment;+++[I3L2J6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459730};+++[I3L2M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459787}; Flags: Fragment;+++[I3L327_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460131}; Flags: Fragment;+++[I3L3C5_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460344};+++[I3L3C6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460350}; Flags: Fragment;+++[I3L3J7_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460492};+++[I3L4A3_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461101}; Flags: Fragment;+++[I3L4C2_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461144};+++[I3L526_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461736}; Flags: Fragment;"]
[10459,"'MAD2L2'",311,311,322,314.666666666667,"04110///Cell cycle+++05100///Bacterial invasion of epithelial cells+++04114///Oocyte meiosis+++05131///Shigellosis+++04914///Progesterone-mediated oocyte maturation","H00238///Fanconi anemia","M00293///DNA polymerase zeta complex",null,"GO:0005730///nucleolus+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0016035///zeta DNA polymerase complex+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex","GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0008432///JUN kinase binding+++GO:0005515///protein binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0006281///DNA repair+++GO:0042772///DNA damage response, signal transduction resulting in transcription+++GO:0045830///positive regulation of isotype switching+++GO:0006302///double-strand break repair+++GO:0042177///negative regulation of protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0042276///error-prone translesion synthesis+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007015///actin filament organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:0051301///cell division+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining","mitotic arrest deficient 2 like 2","[MD2L2_HUMAN|Reviewed]RecName: Full=Mitotic spindle assembly checkpoint protein MAD2B; AltName: Full=Mitotic arrest deficient 2-like protein 2; Short=MAD2-like protein 2; AltName: Full=REV7 homolog; Short=hREV7;+++[A0A024R4I4_HUMAN|Unreviewed]SubName: Full=MAD2 mitotic arrest deficient-like 2 (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71698.1};+++[B1AK43_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000411807}; Flags: Fragment;+++[B1AK44_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000365857};+++[B1AK45_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000400982}; Flags: Fragment;"]
[10460,"'TACC3'",96,122,108,108.666666666667,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0072686///mitotic spindle+++GO:0005819///spindle+++GO:0005815///microtubule organizing center+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005515///protein binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization+++GO:1902850///microtubule cytoskeleton organization involved in mitosis+++GO:0060236///regulation of mitotic spindle organization","transforming acidic coiled-coil containing protein 3","[TACC3_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 3; AltName: Full=ERIC-1;+++[C9JA91_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418095}; Flags: Fragment;+++[C9JWI7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000419210}; Flags: Fragment;+++[E7EMT0_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000415914}; Flags: Fragment;+++[F8WC55_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418727};+++[H0Y8F2_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000420838}; Flags: Fragment;+++[Q8IX09_HUMAN|Unreviewed]SubName: Full=Erythropoietin induced cDNA-1 transcript variant 2 {ECO:0000313|EMBL:AAN76993.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000478580};"]
[10461,"'MERTK'",125,199,150,158,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016028///rhabdomere+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0001750///photoreceptor outer segment","GO:0000166///nucleotide binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0017147///Wnt-protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity","GO:0030154///cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0060068///vagina development+++GO:0032940///secretion by cell+++GO:0030168///platelet activation+++GO:0097350///neutrophil clearance+++GO:0001779///natural killer cell differentiation+++GO:2000107///negative regulation of leukocyte apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0050766///positive regulation of phagocytosis+++GO:0050900///leukocyte migration+++GO:0006909///phagocytosis+++GO:0043277///apoptotic cell clearance+++GO:0009968///negative regulation of signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0007267///cell-cell signaling+++GO:0001818///negative regulation of cytokine production+++GO:0007166///cell surface receptor signaling pathway+++GO:0060041///retina development in camera-type eye+++GO:0016055///Wnt signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0016310///phosphorylation+++GO:0051250///negative regulation of lymphocyte activation+++GO:0018108///peptidyl-tyrosine phosphorylation","MER proto-oncogene, tyrosine kinase","[MERTK_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase Mer; EC=2.7.10.1; AltName: Full=Proto-oncogene c-Mer; AltName: Full=Receptor tyrosine kinase MerTK; Flags: Precursor;+++[A0A087WZQ5_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000482824};+++[E9PD22_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000402129};+++[E9PHX8_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000387277};+++[H7C3L9_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000412660}; Flags: Fragment;+++[Q1RMG3_HUMAN|Unreviewed]SubName: Full=MERTK protein {ECO:0000313|EMBL:AAI14919.1};+++[Q53QW0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAX93144.1}; Flags: Fragment;+++[Q53R53_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAY24213.1}; Flags: Fragment;"]
[10463,"'SLC30A9'",822,724,744,763.333333333333,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008324///cation transmembrane transporter activity+++GO:0016922///nuclear receptor binding","GO:0006289///nucleotide-excision repair+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006812///cation transport+++GO:0006811///ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0006829///zinc ion transport","solute carrier family 30 member 9","[ZNT9_HUMAN|Reviewed]RecName: Full=Zinc transporter 9; Short=ZnT-9; AltName: Full=Human embryonic lung protein {ECO:0000303|PubMed:10409434}; Short=HuEL {ECO:0000303|PubMed:10409434}; AltName: Full=Solute carrier family 30 member 9;+++[A0A024R9W8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 (Zinc transporter), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW92999.1};+++[A0A0S2Z512_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 2 {ECO:0000313|EMBL:ALQ33985.1};+++[A0A0S2Z514_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 1 {ECO:0000313|EMBL:ALQ33984.1}; Flags: Fragment;+++[D6R9M6_HUMAN|Unreviewed]SubName: Full=Zinc transporter 9 {ECO:0000313|Ensembl:ENSP00000423529};"]
[10464,"'PIBF1'",188,210,165,187.666666666667,"03018///RNA degradation+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00530///Joubert syndrome","M00391///Exosome, eukaryotes",null,"GO:0005815///microtubule organizing center+++GO:0034451///centriolar satellite+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005813///centrosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0005136///interleukin-4 receptor binding","GO:0032733///positive regulation of interleukin-10 production+++GO:1905515///non-motile cilium assembly+++GO:0042976///activation of Janus kinase activity+++GO:0071539///protein localization to centrosome+++GO:0090307///mitotic spindle assembly+++GO:0060271///cilium assembly+++GO:0002376///immune system process+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032815///negative regulation of natural killer cell activation+++GO:0031393///negative regulation of prostaglandin biosynthetic process+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0007080///mitotic metaphase plate congression","progesterone immunomodulatory binding factor 1","[PIBF1_HUMAN|Reviewed]RecName: Full=Progesterone-induced-blocking factor 1; Short=PIBF; AltName: Full=Centrosomal protein of 90 kDa; Short=CEP90 {ECO:0000303|PubMed:21224392};+++[A0A087WUI6_HUMAN|Unreviewed]SubName: Full=Progesterone-induced-blocking factor 1 {ECO:0000313|Ensembl:ENSP00000478697};+++[Q05DN0_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH06009.1}; Flags: Fragment;+++[Q4G0R1_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH41806.1};"]
[10465,"'PPIH'",135,117,93,115,"03040///Spliceosome",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0071001///U4/U6 snRNP+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0051082///unfolded protein binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0065003///protein-containing complex assembly","peptidylprolyl isomerase H","[PPIH_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase H; Short=PPIase H; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Rotamase H; AltName: Full=Small nuclear ribonucleoprotein particle-specific cyclophilin H; Short=CypH; AltName: Full=U-snRNP-associated cyclophilin SnuCyp-20; Short=USA-CYP;+++[A6NM32_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000361629};+++[C9JAN8_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000405493}; Flags: Fragment;+++[C9JQD4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[H0YEL5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH36_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH57_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[10466,"'COG5'",358,342,420,373.333333333333,"04140///Autophagy - animal+++04910///Insulin signaling pathway+++04137///Mitophagy - animal","H00119///Congenital disorders of glycosylation (CDG) type II",null,null,"GO:0017119///Golgi transport complex+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0032588///trans-Golgi network membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport","component of oligomeric golgi complex 5","[COG5_HUMAN|Reviewed]RecName: Full=Conserved oligomeric Golgi complex subunit 5; Short=COG complex subunit 5; AltName: Full=13S Golgi transport complex 90 kDa subunit; Short=GTC-90; AltName: Full=Component of oligomeric Golgi complex 5; AltName: Full=Golgi transport complex 1;+++[U3KQU7_HUMAN|Unreviewed]SubName: Full=Conserved oligomeric Golgi complex subunit 5 {ECO:0000313|Ensembl:ENSP00000476238}; Flags: Fragment;"]
[10467,"'ZNHIT1'",1483,1311,1346,1380,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000812///Swr1 complex","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding","GO:0006338///chromatin remodeling+++GO:0031063///regulation of histone deacetylation+++GO:0043486///histone exchange","zinc finger HIT-type containing 1","[ZNHI1_HUMAN|Reviewed]RecName: Full=Zinc finger HIT domain-containing protein 1; AltName: Full=Cyclin-G1-binding protein 1; AltName: Full=Zinc finger protein subfamily 4A member 1; AltName: Full=p18 Hamlet;"]
[10468,"'FST'",42,36,34,37.3333333333333,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048185///activin binding+++GO:0038102///activin receptor antagonist activity","GO:0051798///positive regulation of hair follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032926///negative regulation of activin receptor signaling pathway","follistatin","[FST_HUMAN|Reviewed]RecName: Full=Follistatin; Short=FS; AltName: Full=Activin-binding protein; Flags: Precursor;+++[A0A024QZU6_HUMAN|Unreviewed]SubName: Full=Follistatin, isoform CRA_c {ECO:0000313|EMBL:EAW54883.1};+++[H0YA75_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426315}; Flags: Fragment;+++[H0YAF9_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426971}; Flags: Fragment;+++[Q6FHE1_HUMAN|Unreviewed]SubName: Full=FST protein {ECO:0000313|EMBL:CAG46612.1};"]
[10469,"'TIMM44'",519,580,492,530.333333333333,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0051087///chaperone binding","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix","translocase of inner mitochondrial membrane 44","[TIM44_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM44; Flags: Precursor;+++[M0QXM9_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469273}; Flags: Fragment;+++[M0QXU7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469389}; Flags: Fragment;+++[M0R124_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000471596};+++[M0R301_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000472916}; Flags: Fragment;"]
[1047,"'CLGN'",3346,2547,2096,2663,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005509///calcium ion binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0007338///single fertilization+++GO:0065003///protein-containing complex assembly+++GO:0007339///binding of sperm to zona pellucida","calmegin","[CLGN_HUMAN|Reviewed]RecName: Full=Calmegin; Flags: Precursor;+++[A0A140VKG2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 79P {ECO:0000313|EMBL:AEE61299.1};"]
[10471,"'PFDN6'",228,236,189,217.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016272///prefoldin complex","GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","prefoldin subunit 6","[PFD6_HUMAN|Reviewed]RecName: Full=Prefoldin subunit 6; AltName: Full=Protein Ke2;+++[A2AB88_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6 {ECO:0000313|Ensembl:ENSP00000420135};+++[I7HJT1_HUMAN|Unreviewed]SubName: Full=HLA class II region expressed gene KE2 {ECO:0000313|EMBL:CAC88187.1}; SubName: Full=Prefoldin subunit 6, isoform CRA_a {ECO:0000313|EMBL:EAX03705.1};+++[Q5STK2_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6, isoform CRA_b {ECO:0000313|EMBL:EAX03706.1}; SubName: Full=cDNA, FLJ92435, Homo sapiens HLA class II region expressed gene KE2 (HKE2), mRNA {ECO:0000313|EMBL:BAG35084.1};"]
[10472,"'ZBTB18'",600,685,601,628.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0000228///nuclear chromosome","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0007275///multicellular organism development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 18","[ZBT18_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 18; AltName: Full=58 kDa repressor protein; AltName: Full=Transcriptional repressor RP58; AltName: Full=Translin-associated zinc finger protein 1; Short=TAZ-1; AltName: Full=Zinc finger protein 238; AltName: Full=Zinc finger protein C2H2-171;+++[A0A024R5T6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 238, isoform CRA_a {ECO:0000313|EMBL:EAW77099.1};"]
[10473,"'HMGN4'",340,256,256,284,{"$nulls":4},"GO:0005634///nucleus+++GO:0000785///chromatin","GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding",null,"high mobility group nucleosomal binding domain 4","[HMGN4_HUMAN|Reviewed]RecName: Full=High mobility group nucleosome-binding domain-containing protein 4; AltName: Full=Non-histone chromosomal protein HMG-17-like 3; Short=Non-histone chromosomal protein;+++[A0A024R046_HUMAN|Unreviewed]SubName: Full=High mobility group nucleosomal binding domain 4, isoform CRA_a {ECO:0000313|EMBL:EAW55589.1};"]
[10474,"'TADA3'",2799.1,2900.01,2755.21,2818.10666666667,"05165///Human papillomavirus infection",{"$nulls":3},"GO:0000124///SAGA complex+++GO:0005622///intracellular+++GO:0030914///STAGA complex+++GO:0072686///mitotic spindle+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0033276///transcription factor TFTC complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0016922///nuclear receptor binding+++GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0019904///protein domain specific binding","GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090043///regulation of tubulin deacetylation+++GO:0000278///mitotic cell cycle+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043967///histone H4 acetylation+++GO:0010628///positive regulation of gene expression+++GO:0016579///protein deubiquitination+++GO:0031063///regulation of histone deacetylation+++GO:0001932///regulation of protein phosphorylation+++GO:0031647///regulation of protein stability+++GO:0030520///intracellular estrogen receptor signaling pathway","transcriptional adaptor 3","[TADA3_HUMAN|Reviewed]RecName: Full=Transcriptional adapter 3; AltName: Full=ADA3 homolog; Short=hADA3; AltName: Full=STAF54; AltName: Full=Transcriptional adapter 3-like; Short=ADA3-like protein;+++[A0A024R2D7_HUMAN|Unreviewed]SubName: Full=Transcriptional adaptor 3 (NGG1 homolog, yeast)-like, isoform CRA_a {ECO:0000313|EMBL:EAW63997.1};+++[A8K899_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77724, highly similar to Homo sapiens transcriptional adaptor 3 (NGG1 homolog, yeast)-like (TADA3L), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84953.1};+++[C9JMS0_HUMAN|Unreviewed]SubName: Full=Transcriptional adapter 3 {ECO:0000313|Ensembl:ENSP00000395073}; Flags: Fragment;"]
[10475,"'TRIM38'",286,282,317,295,{"$nulls":4},"GO:0005829///cytosol+++GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050687///negative regulation of defense response to virus+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0046598///positive regulation of viral entry into host cell+++GO:0032648///regulation of interferon-beta production+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0070936///protein K48-linked ubiquitination+++GO:0045087///innate immune response+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","tripartite motif containing 38","[TRI38_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM38; EC=2.3.2.27; AltName: Full=RING finger protein 15; AltName: Full=RING-type E3 ubiquitin transferase TRIM38 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 38; AltName: Full=Zinc finger protein RoRet;+++[A0A024QZY4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 38, isoform CRA_a {ECO:0000313|EMBL:EAW55505.1};"]
[10476,"'ATP5PD'",1165,1143,1063,1123.66666666667,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++05016///Huntington's disease+++05010///Alzheimer's disease+++05012///Parkinson's disease+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0000274///mitochondrial proton-transporting ATP synthase, stator stalk+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005654///nucleoplasm+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005743///mitochondrial inner membrane","GO:0022857///transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0015078///proton transmembrane transporter activity","GO:0015986///ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0006811///ion transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0006754///ATP biosynthetic process+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport","ATP synthase peripheral stalk subunit d","[ATP5H_HUMAN|Reviewed]RecName: Full=ATP synthase subunit d, mitochondrial {ECO:0000305}; Short=ATPase subunit d; AltName: Full=ATP synthase peripheral stalk subunit d {ECO:0000305};+++[A0PJH2_HUMAN|Unreviewed]SubName: Full=ATP5H protein {ECO:0000313|EMBL:AAH29392.1}; Flags: Fragment;+++[F5H608_HUMAN|Unreviewed]SubName: Full=ATP synthase peripheral stalk subunit d {ECO:0000313|Ensembl:ENSP00000437996};+++[L8E9E1_HUMAN|Unreviewed]SubName: Full=Alternative protein ATP5H {ECO:0000313|EMBL:CCQ43351.1};"]
[10477,"'UBE2E3'",909,884,931,908,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0070979///protein K11-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0040008///regulation of growth+++GO:0070936///protein K48-linked ubiquitination","ubiquitin conjugating enzyme E2 E3","[UB2E3_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 E3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme E3; AltName: Full=UbcH9; AltName: Full=Ubiquitin carrier protein E3; AltName: Full=Ubiquitin-conjugating enzyme E2-23 kDa; AltName: Full=Ubiquitin-protein ligase E3;+++[A0A1B0GX65_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473525}; Flags: Fragment;+++[R4GMM6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473264};+++[R4GN77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473521}; Flags: Fragment;+++[R4GND1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473591};+++[R4GNG6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473642};"]
[10478,"'SLC25A17'",288,215,237,246.666666666667,"04146///Peroxisome",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005779///integral component of peroxisomal membrane+++GO:0005778///peroxisomal membrane+++GO:0016021///integral component of membrane+++GO:0005777///peroxisome+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane","GO:0015228///coenzyme A transmembrane transporter activity+++GO:0000295///adenine nucleotide transmembrane transporter activity+++GO:0015230///FAD transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0080122///AMP transmembrane transporter activity+++GO:0005347///ATP transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051087///chaperone binding+++GO:0044610///FMN transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity+++GO:0051724///NAD transmembrane transporter activity","GO:0080121///AMP transport+++GO:0035349///coenzyme A transmembrane transport+++GO:0006635///fatty acid beta-oxidation+++GO:0001561///fatty acid alpha-oxidation+++GO:0015908///fatty acid transport+++GO:0015867///ATP transport+++GO:0015866///ADP transport+++GO:0051182///coenzyme transport+++GO:0035352///NAD transmembrane transport+++GO:0035350///FAD transmembrane transport+++GO:0055085///transmembrane transport+++GO:1901679///nucleotide transmembrane transport","solute carrier family 25 member 17","[PM34_HUMAN|Reviewed]RecName: Full=Peroxisomal membrane protein PMP34; AltName: Full=34 kDa peroxisomal membrane protein; AltName: Full=Solute carrier family 25 member 17;+++[B0QYW5_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000385303};+++[B1AHN4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000404200}; Flags: Fragment;+++[B4DP73_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57410, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG60485.1};+++[B4DU97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57596, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG62259.1};+++[F2Z2I9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000410565};+++[F6RTR7_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000438355};+++[F8WA85_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000263255};+++[F8WBA4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000390502};+++[F8WCH6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000400053};+++[F8WCN9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000416618};+++[F8WE74_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000394539};+++[F8WEC6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000388966};+++[F8WF87_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000407096};"]
[10479,"'SLC9A6'",312,294,274,293.333333333333,null,"H01914///Christianson syndrome",null,null,"GO:0043679///axon terminus+++GO:0030425///dendrite+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0031901///early endosome membrane+++GO:0044308///axonal spine+++GO:0005770///late endosome+++GO:0005789///endoplasmic reticulum membrane","GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity","GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0050808///synapse organization+++GO:0098719///sodium ion import across plasma membrane+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway+++GO:0060996///dendritic spine development+++GO:0048675///axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0051453///regulation of intracellular pH+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0097484///dendrite extension","solute carrier family 9 member A6","[SL9A6_HUMAN|Reviewed]RecName: Full=Sodium/hydrogen exchanger 6; AltName: Full=Na(+)/H(+) exchanger 6; Short=NHE-6; AltName: Full=Solute carrier family 9 member 6;+++[A0A1B0GV11_HUMAN|Unreviewed]RecName: Full=Sodium/hydrogen exchanger {ECO:0000256|RuleBase:RU003722};"]
[1048,"'CEACAM5'",2,1,0,1,{"$nulls":4},"GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0071575///integral component of external side of plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0031225///anchored component of membrane+++GO:0016324///apical plasma membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity+++GO:0034235///GPI anchor binding+++GO:0042802///identical protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034109///homotypic cell-cell adhesion+++GO:0010832///negative regulation of myotube differentiation+++GO:2000811///negative regulation of anoikis+++GO:0050900///leukocyte migration","carcinoembryonic antigen related cell adhesion molecule 5","[CEAM5_HUMAN|Reviewed]RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5; AltName: Full=Carcinoembryonic antigen; Short=CEA; AltName: Full=Meconium antigen 100; AltName: CD_antigen=CD66e; Flags: Precursor;+++[A0A024R0K5_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5, isoform CRA_a {ECO:0000313|EMBL:EAW57060.1};+++[A0A087WYX0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000482157};+++[M0QX98_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000468997}; Flags: Fragment;+++[M0R3J1_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000473252}; Flags: Fragment;+++[Q53G30_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 variant {ECO:0000313|EMBL:BAD96821.1}; Flags: Fragment;+++[Q8N4D0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|EMBL:AAH34671.1};+++[T2HUW8_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 3D {ECO:0000313|EMBL:BAN83790.1};+++[T2HVB7_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 5D {ECO:0000313|EMBL:BAN83789.1};"]
[10480,"'EIF3M'",1198,1173,1076,1149,{"$nulls":4},"GO:0033290///eukaryotic 48S preinitiation complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0031369///translation initiation factor binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006412///translation+++GO:0006413///translational initiation+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation","eukaryotic translation initiation factor 3 subunit M","[EIF3M_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000255|HAMAP-Rule:MF_03012}; Short=eIF3m {ECO:0000255|HAMAP-Rule:MF_03012}; AltName: Full=Fetal lung protein B5; Short=hFL-B5; AltName: Full=PCI domain-containing protein 1;+++[E7ESM3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435501};+++[E9PN86_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432891}; Flags: Fragment;+++[E9PRI2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432286};+++[E9PRY0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000434080};+++[E9PSB3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435834};+++[H0YCQ8_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432139}; Flags: Fragment;+++[J3KNJ2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000319910}; Flags: Fragment;"]
[10482,"'NXF1'",1136,1302,1212,1216.66666666667,"05168///Herpes simplex infection+++03013///RNA transport+++03015///mRNA surveillance pathway+++05164///Influenza A+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0000346///transcription export complex+++GO:0042405///nuclear inclusion body+++GO:0005737///cytoplasm+++GO:0005643///nuclear pore+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding","GO:0051028///mRNA transport+++GO:0016032///viral process+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus","nuclear RNA export factor 1","[NXF1_HUMAN|Reviewed]RecName: Full=Nuclear RNA export factor 1; AltName: Full=Tip-associated protein; AltName: Full=Tip-associating protein; AltName: Full=mRNA export factor TAP;+++[A0A024R5A9_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW74104.1};+++[B4E227_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61053, highly similar to Nuclear RNA export factor 1 {ECO:0000313|EMBL:BAG64989.1};+++[E9PIN3_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000435742}; Flags: Fragment;+++[E9PLA7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000431381}; Flags: Fragment;+++[E9PMV7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000437296}; Flags: Fragment;+++[E9PQA4_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000432530};+++[H0YDU0_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000434301}; Flags: Fragment;+++[Q59E96_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 variant {ECO:0000313|EMBL:BAD93152.1}; Flags: Fragment;"]
[10483,"'SEC23B'",980,942,988,970,"04141///Protein processing in endoplasmic reticulum","H01105///Cranio-lenticulo-sutural dysplasia (CLSD)+++H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)","M00404///COPII complex",null,"GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0012505///endomembrane system+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0008360///regulation of cell shape+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090114///COPII-coated vesicle budding+++GO:0003400///regulation of COPII vesicle coating","Sec23 homolog B, coat complex II component","[SC23B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23B {ECO:0000305}; Short=hSec23B {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein B;+++[A0A2R8Y633_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8Y7S7_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YF30_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YFH5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[Q5QPE1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[Q5QPE2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;"]
[10484,"'SEC23A'",1660,1481,1522,1554.33333333333,"04141///Protein processing in endoplasmic reticulum","H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)+++H01105///Cranio-lenticulo-sutural dysplasia (CLSD)","M00404///COPII complex",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030127///COPII vesicle coat+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0019898///extrinsic component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0070971///endoplasmic reticulum exit site","GO:0005096///GTPase activator activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0090114///COPII-coated vesicle budding+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0015031///protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0003400///regulation of COPII vesicle coating+++GO:0008360///regulation of cell shape+++GO:0007030///Golgi organization+++GO:0006886///intracellular protein transport+++GO:0048208///COPII vesicle coating+++GO:0043547///positive regulation of GTPase activity","Sec23 homolog A, coat complex II component","[SC23A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23A {ECO:0000305}; Short=hSec23A {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein A;+++[F5H365_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V1W4_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V2R6_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V3G5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V4Q2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V4V1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5K1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5X8_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[L8ECD0_HUMAN|Unreviewed]SubName: Full=Alternative protein SEC23A {ECO:0000313|EMBL:CCQ43352.1};"]
[10485,"'C1orf61'",5,7,2.84,4.94666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003674///molecular_function","GO:0045944///positive regulation of transcription by RNA polymerase II","chromosome 1 open reading frame 61","[CROC4_HUMAN|Reviewed]RecName: Full=Protein CROC-4; AltName: Full=Contingent replication of cDNA 4;+++[H0Y3T1_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000383776}; Flags: Fragment;+++[H3BLW3_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000357225}; Flags: Fragment;+++[Q6PB34_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH59943.1}; Flags: Fragment;+++[Q86W69_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH50448.1}; SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000310651}; Flags: Fragment;+++[X6R5L4_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000350661}; Flags: Fragment;"]
[10486,"'CAP2'",2247,2065,2181,2164.33333333333,"04137///Mitophagy - animal+++03010///Ribosome+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly","M00177///Ribosome, eukaryotes",null,"GO:0005886///plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:1990904///ribonucleoprotein complex","GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008179///adenylate cyclase binding+++GO:0042803///protein homodimerization activity+++GO:0003779///actin binding+++GO:0042802///identical protein binding","GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0007190///activation of adenylate cyclase activity+++GO:0002181///cytoplasmic translation+++GO:0007163///establishment or maintenance of cell polarity+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0006364///rRNA processing+++GO:0008154///actin polymerization or depolymerization+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0007165///signal transduction+++GO:0000902///cell morphogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","cyclase associated actin cytoskeleton regulatory protein 2","[CAP2_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 2; Short=CAP 2;+++[A0A087WZ15_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[A0A087X0J3_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[B7Z385_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[E9PDI2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[F8WDB9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000420615};+++[F8WEW0_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000419906};+++[Q5JPJ8_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};"]
[10487,"'CAP1'",5466,4357,4857,4893.33333333333,"01100///Metabolic pathways+++04142///Lysosome+++01212///Fatty acid metabolism+++00062///Fatty acid elongation","H00149///Neuronal ceroid lipofuscinosis (NCL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,"R01274///palmitoyl-CoA hydrolase Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid","GO:0035578///azurophil granule lumen+++GO:0030424///axon+++GO:0005764///lysosome+++GO:0030425///dendrite+++GO:0045121///membrane raft+++GO:0005794///Golgi apparatus+++GO:0030864///cortical actin cytoskeleton+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0043025///neuronal cell body+++GO:0043202///lysosomal lumen+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0008179///adenylate cyclase binding+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0003779///actin binding","GO:0030163///protein catabolic process+++GO:0007269///neurotransmitter secretion+++GO:0006898///receptor-mediated endocytosis+++GO:0007042///lysosomal lumen acidification+++GO:0001667///ameboidal-type cell migration+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0008154///actin polymerization or depolymerization+++GO:0007420///brain development+++GO:0030149///sphingolipid catabolic process+++GO:0007601///visual perception+++GO:0007190///activation of adenylate cyclase activity+++GO:0051186///cofactor metabolic process+++GO:0016042///lipid catabolic process+++GO:0046949///fatty-acyl-CoA biosynthetic process+++GO:0043312///neutrophil degranulation+++GO:0051181///cofactor transport+++GO:0050803///regulation of synapse structure or activity+++GO:0002084///protein depalmitoylation+++GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0007268///chemical synaptic transmission+++GO:0006907///pinocytosis+++GO:0050896///response to stimulus+++GO:0048666///neuron development+++GO:0000902///cell morphogenesis+++GO:0007165///signal transduction+++GO:0032429///regulation of phospholipase A2 activity+++GO:0007625///grooming behavior+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048549///positive regulation of pinocytosis+++GO:0044257///cellular protein catabolic process+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0031579///membrane raft organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0030308///negative regulation of cell growth+++GO:0043066///negative regulation of apoptotic process","cyclase associated actin cytoskeleton regulatory protein 1","[CAP1_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 1; Short=CAP 1;+++[D3DPU2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[L8EAI0_HUMAN|Unreviewed]SubName: Full=Alternative protein CAP1 {ECO:0000313|EMBL:CCQ43353.1};+++[Q5T0R1_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413656}; Flags: Fragment;+++[Q5T0R2_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408561}; Flags: Fragment;+++[Q5T0R3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000403198}; Flags: Fragment;+++[Q5T0R4_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413383}; Flags: Fragment;+++[Q5T0R5_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000410586}; Flags: Fragment;+++[Q5T0R6_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000400943}; Flags: Fragment;+++[Q5T0R7_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398475}; Flags: Fragment;+++[Q5T0R8_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000389974}; Flags: Fragment;+++[Q5T0R9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000412859}; Flags: Fragment;+++[Q5T0S3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398877}; Flags: Fragment;"]
[10488,"'CREB3'",1148,1101,1122,1123.66666666667,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05163///Human cytomegalovirus infection+++04668///TNF signaling pathway+++04714///Thermogenesis+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++04922///Glucagon signaling pathway+++04911///Insulin secretion+++04962///Vasopressin-regulated water reabsorption+++05215///Prostate cancer+++05034///Alcoholism+++05030///Cocaine addiction+++04928///Parathyroid hormone synthesis, secretion and action+++05031///Amphetamine addiction+++04024///cAMP signaling pathway+++04926///Relaxin signaling pathway+++04725///Cholinergic synapse+++04927///Cortisol synthesis and secretion+++05016///Huntington's disease+++05203///Viral carcinogenesis+++04925///Aldosterone synthesis and secretion+++04022///cGMP-PKG signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04211///Longevity regulating pathway+++05165///Human papillomavirus infection+++04934///Cushing's syndrome+++05161///Hepatitis B+++04916///Melanogenesis+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0008140///cAMP response element binding protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:0003682///chromatin binding+++GO:0031726///CCR1 chemokine receptor binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000982///transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0019043///establishment of viral latency+++GO:0001558///regulation of cell growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0051928///positive regulation of calcium ion transport+++GO:0042981///regulation of apoptotic process+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090045///positive regulation of deacetylase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000326///negative regulation of nuclear receptor transcription coactivator activity+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0006990///positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0006351///transcription, DNA-templated+++GO:0019046///release from viral latency+++GO:0016032///viral process+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006935///chemotaxis+++GO:0050930///induction of positive chemotaxis","cAMP responsive element binding protein 3","[CREB3_HUMAN|Reviewed]RecName: Full=Cyclic AMP-responsive element-binding protein 3; Short=CREB-3; Short=cAMP-responsive element-binding protein 3; AltName: Full=Leucine zipper protein; AltName: Full=Luman; AltName: Full=Transcription factor LZIP-alpha; Contains: RecName: Full=Processed cyclic AMP-responsive element-binding protein 3; Short=N-terminal Luman; Short=Transcriptionally active form;"]
[10489,"'LRRC41'",1599,1784,1552,1645,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity","GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination","leucine rich repeat containing 41","[LRC41_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 41; AltName: Full=Protein Muf1;+++[A0A087WTI9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000477909}; Flags: Fragment;+++[A0A087WTU1_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000478135};+++[A0A087X0S7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000483633};+++[A0A0B4J2G4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484752};+++[A0A0C4DH00_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484558};+++[Q562F1_HUMAN|Unreviewed]SubName: Full=LRRC41 protein {ECO:0000313|EMBL:AAH92479.1}; Flags: Fragment;"]
[10490,"'VTI1B'",985,1037,875,965.666666666667,"04138///Autophagy - yeast+++04130///SNARE interactions in vesicular transport","H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00186///Hyperargininemia","M00029///Urea cycle+++M00134///Polyamine biosynthesis, arginine => ornithine => putrescine","R00551///L-Arginine amidinohydrolase L-Arginine + H2O <=> L-Ornithine + Urea","GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031093///platelet alpha granule lumen+++GO:0005829///cytosol+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043025///neuronal cell body+++GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0055037///recycling endosome+++GO:0005764///lysosome+++GO:0031901///early endosome membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0031201///SNARE complex+++GO:0005576///extracellular region+++GO:0008021///synaptic vesicle","GO:0005484///SNAP receptor activity+++GO:0019869///chloride channel inhibitor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0002576///platelet degranulation+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006623///protein targeting to vacuole+++GO:0006896///Golgi to vacuole transport+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0008283///cell proliferation+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0097352///autophagosome maturation","vesicle transport through interaction with t-SNAREs 1B","[VTI1B_HUMAN|Reviewed]RecName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B; AltName: Full=Vesicle transport v-SNARE protein Vti1-like 1; AltName: Full=Vti1-rp1;+++[G3V5I2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000452366};+++[H0YJJ5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451661}; Flags: Fragment;+++[H0YJL5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451759}; Flags: Fragment;+++[J3KMW2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000216456};"]
[104909134,"'LINC02210-CRHR1'",61,34,43,46,{"$nulls":4},"GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0015056///corticotrophin-releasing factor receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0051458///corticotropin secretion+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:2000852///regulation of corticosterone secretion","LINC02210-CRHR1 readthrough","[CRFR1_HUMAN|Reviewed]RecName: Full=Corticotropin-releasing factor receptor 1; Short=CRF-R-1; Short=CRF-R1; Short=CRFR-1; AltName: Full=Corticotropin-releasing hormone receptor 1; Short=CRH-R-1; Short=CRH-R1; Flags: Precursor;+++[A0A024R9X9_HUMAN|Unreviewed]SubName: Full=Corticotropin releasing hormone receptor 1, isoform CRA_b {ECO:0000313|EMBL:EAW93558.1};+++[B4DMR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60308, highly similar to Corticotropin-releasing factor receptor 1 {ECO:0000313|EMBL:BAG59977.1};"]
[10491,"'CRTAP'",6449,5812,5708,5989.66666666667,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0050821///protein stabilization+++GO:0007283///spermatogenesis+++GO:0018400///peptidyl-proline hydroxylation to 3-hydroxy-L-proline+++GO:0061077///chaperone-mediated protein folding+++GO:1901874///negative regulation of post-translational protein modification","cartilage associated protein","[CRTAP_HUMAN|Reviewed]RecName: Full=Cartilage-associated protein; Flags: Precursor;+++[B4DPA3_HUMAN|Unreviewed]SubName: Full=Cartilage associated protein, isoform CRA_a {ECO:0000313|EMBL:EAW64448.1}; SubName: Full=cDNA FLJ55123, highly similar to Cartilage-associated protein {ECO:0000313|EMBL:BAG60515.1};+++[C9JP16_HUMAN|Unreviewed]SubName: Full=Cartilage-associated protein {ECO:0000313|Ensembl:ENSP00000409997};"]
[10492,"'SYNCRIP'",1756,1506,1517,1593,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0097452///GAIT complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0070937///CRD-mediated mRNA stability complex+++GO:1990904///ribonucleoprotein complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm","GO:0008143///poly(A) binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0001649///osteoblast differentiation+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0006397///mRNA processing+++GO:0016032///viral process+++GO:0071346///cellular response to interferon-gamma+++GO:0006396///RNA processing+++GO:0000398///mRNA splicing, via spliceosome","synaptotagmin binding cytoplasmic RNA interacting protein","[HNRPQ_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein Q; Short=hnRNP Q; AltName: Full=Glycine- and tyrosine-rich RNA-binding protein; Short=GRY-RBP; AltName: Full=NS1-associated protein 1; AltName: Full=Synaptotagmin-binding, cytoplasmic RNA-interacting protein;+++[B7Z645_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein, isoform CRA_b {ECO:0000313|EMBL:EAW48623.1}; SubName: Full=cDNA FLJ50849, highly similar to Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|EMBL:BAH13131.1};+++[F6UXX1_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|Ensembl:ENSP00000397782}; Flags: Fragment;+++[Q05CK9_HUMAN|Unreviewed]SubName: Full=SYNCRIP protein {ECO:0000313|EMBL:AAH24283.1}; Flags: Fragment;+++[Q59GL1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein variant {ECO:0000313|EMBL:BAD92335.1}; Flags: Fragment;"]
[10493,"'VAT1'",6529,6092,5784,6135,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0035578///azurophil granule lumen+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity","GO:0010637///negative regulation of mitochondrial fusion+++GO:0060337///type I interferon signaling pathway+++GO:0043312///neutrophil degranulation","vesicle amine transport 1","[VAT1_HUMAN|Reviewed]RecName: Full=Synaptic vesicle membrane protein VAT-1 homolog; EC=1.-.-.-;+++[A0A024R1Z6_HUMAN|Unreviewed]SubName: Full=Vesicle amine transport protein 1 homolog (T californica), isoform CRA_a {ECO:0000313|EMBL:EAW60918.1};+++[K7EJM4_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000465239}; Flags: Fragment;+++[K7EM19_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000466322}; Flags: Fragment;+++[K7ENX2_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000467131}; Flags: Fragment;+++[K7ER81_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468146}; Flags: Fragment;+++[K7ERT7_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468401}; Flags: Fragment;+++[K7ESA3_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468621}; Flags: Fragment;"]
[10494,"'STK25'",2204,2211,2039,2151.33333333333,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding","GO:0023014///signal transduction by protein phosphorylation+++GO:0051683///establishment of Golgi localization+++GO:0006979///response to oxidative stress+++GO:0090168///Golgi reassembly+++GO:0036481///intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0006468///protein phosphorylation+++GO:0050772///positive regulation of axonogenesis+++GO:0046777///protein autophosphorylation+++GO:0016310///phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0007163///establishment or maintenance of cell polarity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051645///Golgi localization","serine/threonine kinase 25","[STK25_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 25; EC=2.7.11.1; AltName: Full=Ste20-like kinase; AltName: Full=Sterile 20/oxidant stress-response kinase 1; Short=SOK-1; Short=Ste20/oxidant stress response kinase 1;+++[A0A024R4B2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71266.1}; SubName: Full=Serine/threonine kinase 25 isoform 1 {ECO:0000313|EMBL:ALQ33986.1};+++[A0A0S2Z4Y2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 3 {ECO:0000313|EMBL:ALQ33988.1}; Flags: Fragment;+++[A0A0S2Z503_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 2 {ECO:0000313|EMBL:ALQ33987.1};+++[B3KRS6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34842 fis, clone NT2NE2011033, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG52488.1};+++[B4DMA5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59346, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG59817.1};+++[B4DVS7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52778, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG62789.1};+++[B4E185_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61527, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG64697.1};+++[C9J232_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000399212}; Flags: Fragment;+++[C9J6L2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000417020}; Flags: Fragment;+++[C9J8E8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000406208}; Flags: Fragment;+++[C9JCC0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403607}; Flags: Fragment;+++[C9JDH9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000395104}; Flags: Fragment;+++[C9JFA1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404552}; Flags: Fragment;+++[C9JIH8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403866}; Flags: Fragment;+++[C9JJV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404960}; Flags: Fragment;+++[C9JN58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000414191}; Flags: Fragment;+++[C9K0M6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000401114}; Flags: Fragment;+++[E7EM58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000412617}; Flags: Fragment;+++[H7C279_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404469}; Flags: Fragment;+++[Q96BA2_HUMAN|Unreviewed]SubName: Full=STK25 protein {ECO:0000313|EMBL:AAH15793.1};"]
[10495,"'ENOX2'",169,193,148,170,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0009897///external side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0016491///oxidoreductase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0005515///protein binding","GO:0048511///rhythmic process+++GO:0007624///ultradian rhythm+++GO:0055114///oxidation-reduction process+++GO:0040008///regulation of growth","ecto-NOX disulfide-thiol exchanger 2","[ENOX2_HUMAN|Reviewed]RecName: Full=Ecto-NOX disulfide-thiol exchanger 2; AltName: Full=APK1 antigen; AltName: Full=Cytosolic ovarian carcinoma antigen 1; AltName: Full=Tumor-associated hydroquinone oxidase; Short=tNOX; Includes: RecName: Full=Hydroquinone [NADH] oxidase; EC=1.-.-.-; Includes: RecName: Full=Protein disulfide-thiol oxidoreductase; EC=1.-.-.-;+++[A0A0C4DGT9_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000478608};+++[A4QPE1_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI39782.2}; Flags: Fragment;+++[B1AKF7_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000400304}; Flags: Fragment;+++[Q32ND0_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI08714.1}; Flags: Fragment;"]
[10497,"'UNC13B'",927,1021,1056,1001.33333333333,"04721///Synaptic vesicle cycle",{"$nulls":3},"GO:0097470///ribbon synapse+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0045202///synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0030672///synaptic vesicle membrane+++GO:0032009///early phagosome+++GO:0048786///presynaptic active zone+++GO:0031594///neuromuscular junction+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098793///presynapse+++GO:0043195///terminal bouton+++GO:0005794///Golgi apparatus+++GO:0044305///calyx of Held+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0017137///Rab GTPase binding+++GO:0030742///GTP-dependent protein binding+++GO:0005516///calmodulin binding+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0006887///exocytosis+++GO:0010808///positive regulation of synaptic vesicle priming+++GO:1900426///positive regulation of defense response to bacterium+++GO:0007268///chemical synaptic transmission+++GO:0050714///positive regulation of protein secretion+++GO:0035556///intracellular signal transduction+++GO:0016081///synaptic vesicle docking+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0061789///dense core granule priming+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0043065///positive regulation of apoptotic process+++GO:0060384///innervation+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:0007528///neuromuscular junction development+++GO:0035249///synaptic transmission, glutamatergic+++GO:0090382///phagosome maturation+++GO:0071333///cellular response to glucose stimulus+++GO:0016079///synaptic vesicle exocytosis+++GO:0031914///negative regulation of synaptic plasticity","unc-13 homolog B","[UN13B_HUMAN|Reviewed]RecName: Full=Protein unc-13 homolog B; AltName: Full=Munc13-2; Short=munc13;+++[A0A0U1RRB5_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489441}; Flags: Fragment;+++[A0A0U1RRL2_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489581};+++[A0A1B0GUS7_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490228};+++[A0A1B0GVW8_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490683};+++[B1AM27_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000380006};+++[F8W8M9_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000367757};+++[I6L9J0_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000484432}; SubName: Full=UNC13B protein {ECO:0000313|EMBL:AAI11801.1};+++[Q4LE73_HUMAN|Unreviewed]SubName: Full=UNC13B variant protein {ECO:0000313|EMBL:BAE06080.1}; Flags: Fragment;"]
[10498,"'CARM1'",2165,2127,1947,2079.66666666667,"01522///Endocrine resistance",null,null,"R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0042054///histone methyltransferase activity+++GO:0035642///histone methyltransferase activity (H3-R17 specific)+++GO:0042803///protein homodimerization activity+++GO:0070577///lysine-acetylated histone binding+++GO:0008013///beta-catenin binding+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0016274///protein-arginine N-methyltransferase activity","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0016571///histone methylation+++GO:0071168///protein localization to chromatin+++GO:0019216///regulation of lipid metabolic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006479///protein methylation+++GO:0032259///methylation+++GO:0034971///histone H3-R17 methylation+++GO:0060350///endochondral bone morphogenesis+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0016032///viral process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0051591///response to cAMP+++GO:1902415///regulation of mRNA binding+++GO:0034970///histone H3-R2 methylation+++GO:0003420///regulation of growth plate cartilage chondrocyte proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0006325///chromatin organization+++GO:0007568///aging+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:2000171///negative regulation of dendrite development+++GO:0032091///negative regulation of protein binding+++GO:0034969///histone arginine methylation","coactivator associated arginine methyltransferase 1","[CARM1_HUMAN|Reviewed]RecName: Full=Histone-arginine methyltransferase CARM1; EC=2.1.1.319 {ECO:0000269|PubMed:19405910}; AltName: Full=Coactivator-associated arginine methyltransferase 1; AltName: Full=Protein arginine N-methyltransferase 4;+++[K7EIQ8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000464852}; Flags: Fragment;+++[K7EK20_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000465417}; Flags: Fragment;+++[K7EPK1_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467420};+++[K7EQA8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467746}; Flags: Fragment;+++[K7EQB9_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467761}; Flags: Fragment;+++[K7ERM3_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000468319}; Flags: Fragment;"]
[10499,"'NCOA2'",498,567,502,522.333333333333,"04915///Estrogen signaling pathway+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0005102///signaling receptor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0019904///protein domain specific binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0035257///nuclear hormone receptor binding+++GO:0016922///nuclear receptor binding+++GO:0003713///transcription coactivator activity","GO:0048511///rhythmic process+++GO:0032570///response to progesterone+++GO:0015721///bile acid and bile salt transport+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010906///regulation of glucose metabolic process+++GO:0007623///circadian rhythm+++GO:0032870///cellular response to hormone stimulus+++GO:0045475///locomotor rhythm+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0032922///circadian regulation of gene expression+++GO:1904017///cellular response to Thyroglobulin triiodothyronine+++GO:0019216///regulation of lipid metabolic process+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II","nuclear receptor coactivator 2","[NCOA2_HUMAN|Reviewed]RecName: Full=Nuclear receptor coactivator 2; Short=NCoA-2; AltName: Full=Class E basic helix-loop-helix protein 75; Short=bHLHe75; AltName: Full=Transcriptional intermediary factor 2; Short=hTIF2;+++[A0A0B6XJZ8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|EMBL:CEF49517.1}; Flags: Fragment;+++[A0A1D5RMT0_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430850}; Flags: Fragment;+++[B4DPW8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51272, highly similar to Nuclear receptor coactivator 2 {ECO:0000313|EMBL:BAG60730.1};+++[E5RFN9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430348}; Flags: Fragment;+++[E7EWM1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430148};+++[H0YBB6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000429132}; Flags: Fragment;+++[Q569J4_HUMAN|Unreviewed]SubName: Full=NCOA2 protein {ECO:0000313|EMBL:AAH92442.1};"]
[1050,"'CEBPA'",27,19,19,21.6666666666667,"05221///Acute myeloid leukemia+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05202///Transcriptional misregulation in cancer+++05200///Pathways in cancer","H00003///Acute myeloid leukemia (AML)",null,null,"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001013///RNA polymerase I regulatory region DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0001892///embryonic placenta development+++GO:0008285///negative regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0030225///macrophage differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006351///transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0030851///granulocyte differentiation+++GO:0050873///brown fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071285///cellular response to lithium ion+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0043032///positive regulation of macrophage activation+++GO:0055088///lipid homeostasis+++GO:0030324///lung development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0045444///fat cell differentiation+++GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000050///urea cycle+++GO:0030099///myeloid cell differentiation+++GO:0008203///cholesterol metabolic process+++GO:0007005///mitochondrion organization+++GO:0048839///inner ear development+++GO:0050872///white fat cell differentiation+++GO:0071407///cellular response to organic cyclic compound+++GO:0048469///cell maturation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006091///generation of precursor metabolites and energy+++GO:0007219///Notch signaling pathway+++GO:0042593///glucose homeostasis+++GO:0006360///transcription by RNA polymerase I","CCAAT enhancer binding protein alpha","[CEBPA_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein alpha {ECO:0000312|HGNC:HGNC:1833}; Short=C/EBP alpha {ECO:0000312|HGNC:HGNC:1833};"]
[10500,"'SEMA6C'",129,126,119,124.666666666667,"04360///Axon guidance",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface","GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0001755///neural crest cell migration+++GO:0030335///positive regulation of cell migration+++GO:0050919///negative chemotaxis+++GO:0007399///nervous system development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0030517///negative regulation of axon extension+++GO:0030154///cell differentiation+++GO:0048843///negative regulation of axon extension involved in axon guidance","semaphorin 6C","[SEM6C_HUMAN|Reviewed]RecName: Full=Semaphorin-6C; AltName: Full=Semaphorin-Y; Short=Sema Y; Flags: Precursor;+++[A0A087WYX3_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000482163};+++[A0A087X0A5_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000483227};+++[Q1RMY5_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14624.1};+++[Q24JR3_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14522.1};"]
[10501,"'SEMA6B'",803,739,645,729,"04360///Axon guidance",{"$nulls":3},"GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0030335///positive regulation of cell migration+++GO:0030154///cell differentiation+++GO:0007399///nervous system development","semaphorin 6B","[SEM6B_HUMAN|Reviewed]RecName: Full=Semaphorin-6B; AltName: Full=Semaphorin-Z; Short=Sema Z; Flags: Precursor;+++[Q9BXR8_HUMAN|Unreviewed]SubName: Full=Semaphorin 6B isoform 2 {ECO:0000313|EMBL:AAK16831.1};"]
[10505,"'SEMA4F'",394,392.47,371.92,386.13,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0031290///retinal ganglion cell axon guidance+++GO:0030154///cell differentiation+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0001755///neural crest cell migration+++GO:0007411///axon guidance+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis","ssemaphorin 4F","[SEM4F_HUMAN|Reviewed]RecName: Full=Semaphorin-4F; AltName: Full=Semaphorin-M; Short=Sema M; AltName: Full=Semaphorin-W; Short=Sema W; Flags: Precursor;+++[A0A087WYZ7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000482238};+++[B7Z931_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52836, highly similar to Semaphorin-4F {ECO:0000313|EMBL:BAH14167.1};+++[C9JKW7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000409141}; Flags: Fragment;+++[C9K0A1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000407698}; Flags: Fragment;+++[F8WCP8_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000416490};+++[F8WD61_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000396703};+++[F8WEH3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000413882};"]
[10507,"'SEMA4D'",287.49,303.96,265.51,285.653333333333,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0004888///transmembrane signaling receptor activity","GO:0008360///regulation of cell shape+++GO:0030335///positive regulation of cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0050919///negative chemotaxis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0050772///positive regulation of axonogenesis+++GO:0007275///multicellular organism development+++GO:0006955///immune response+++GO:0048814///regulation of dendrite morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:1900220///semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis+++GO:0048672///positive regulation of collateral sprouting+++GO:0070486///leukocyte aggregation+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0043931///ossification involved in bone maturation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0007155///cell adhesion+++GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0030154///cell differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007399///nervous system development+++GO:0043547///positive regulation of GTPase activity+++GO:0031344///regulation of cell projection organization+++GO:0045668///negative regulation of osteoblast differentiation","semaphorin 4D","[SEM4D_HUMAN|Reviewed]RecName: Full=Semaphorin-4D; AltName: Full=A8; AltName: Full=BB18; AltName: Full=GR3; AltName: CD_antigen=CD100; Flags: Precursor;+++[A0A0C4DG45_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000399948};+++[C9JD54_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000416747}; Flags: Fragment;+++[C9JFP1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000390754}; Flags: Fragment;+++[C9JYS7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000413352}; Flags: Fragment;+++[E9PFD9_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000395222};+++[F5H044_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000438389}; Flags: Fragment;+++[Q4LE41_HUMAN|Unreviewed]SubName: Full=SEMA4D variant protein {ECO:0000313|EMBL:BAE06112.1}; Flags: Fragment;"]
[10509,"'SEMA4B'",493,532,560,528.333333333333,"04360///Axon guidance","H00527///Retinitis pigmentosa (RP)+++H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0030335///positive regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis+++GO:0030154///cell differentiation+++GO:0071526///semaphorin-plexin signaling pathway","semaphorin 4B","[SEM4B_HUMAN|Reviewed]RecName: Full=Semaphorin-4B; Flags: Precursor;+++[H0YKV7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000452957};+++[H0YLN3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453272}; Flags: Fragment;+++[H0YM68_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453484};+++[H0YMD6_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453563}; Flags: Fragment;+++[H0YMR1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453705}; Flags: Fragment;+++[H0YMZ3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453804}; Flags: Fragment;+++[H0YN49_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453866}; Flags: Fragment;+++[H0YNC4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453951}; Flags: Fragment;+++[H0YNM2_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000454068}; Flags: Fragment;+++[J3KNP4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000332204};+++[Q4VBY2_HUMAN|Unreviewed]SubName: Full=SEMA4B protein {ECO:0000313|EMBL:AAH94849.1}; Flags: Fragment;"]
[1051,"'CEBPB'",1885,1626,1567,1692.66666666667,"05152///Tuberculosis+++04668///TNF signaling pathway+++05202///Transcriptional misregulation in cancer+++04657///IL-17 signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0036488///CHOP-C/EBP complex+++GO:0000779///condensed chromosome, centromeric region+++GO:0000790///nuclear chromatin+++GO:0016363///nuclear matrix+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0035259///glucocorticoid receptor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0042826///histone deacetylase binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0045444///fat cell differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901329///regulation of odontoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0042742///defense response to bacterium+++GO:0045408///regulation of interleukin-6 biosynthetic process+++GO:0035711///T-helper 1 cell activation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0070169///positive regulation of biomineral tissue development+++GO:0032753///positive regulation of interleukin-4 production+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001541///ovarian follicle development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0071347///cellular response to interleukin-1+++GO:0001889///liver development+++GO:0042130///negative regulation of T cell proliferation+++GO:0034976///response to endoplasmic reticulum stress+++GO:2000120///positive regulation of sodium-dependent phosphate transport+++GO:0007613///memory+++GO:0071407///cellular response to organic cyclic compound+++GO:0071230///cellular response to amino acid stimulus+++GO:0001892///embryonic placenta development+++GO:0006366///transcription by RNA polymerase II+++GO:0002432///granuloma formation+++GO:0050873///brown fat cell differentiation+++GO:0097421///liver regeneration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:0045600///positive regulation of fat cell differentiation+++GO:0030182///neuron differentiation+++GO:0072574///hepatocyte proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045670///regulation of osteoclast differentiation+++GO:0030154///cell differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0060850///regulation of transcription involved in cell fate commitment+++GO:2001198///regulation of dendritic cell differentiation","CCAAT enhancer binding protein beta","[CEBPB_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein beta {ECO:0000312|HGNC:HGNC:1834}; Short=C/EBP beta {ECO:0000312|HGNC:HGNC:1834}; AltName: Full=Liver activator protein; Short=LAP; AltName: Full=Liver-enriched inhibitory protein; Short=LIP; AltName: Full=Nuclear factor NF-IL6 {ECO:0000303|PubMed:1741402}; AltName: Full=Transcription factor 5; Short=TCF-5;+++[Q9BSC0_HUMAN|Unreviewed]SubName: Full=CEBPB protein {ECO:0000313|EMBL:AAH05132.2}; Flags: Fragment;+++[W8SNU6_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26745.1}; Flags: Fragment;+++[W8SNV5_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26755.1}; Flags: Fragment;"]
[10512,"'SEMA3C'",4438,4466,4474,4459.33333333333,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0050919///negative chemotaxis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0003350///pulmonary myocardium development+++GO:0006955///immune response+++GO:0060174///limb bud formation+++GO:0140074///cardiac endothelial to mesenchymal transition+++GO:0001755///neural crest cell migration+++GO:0007507///heart development+++GO:0042493///response to drug+++GO:0030154///cell differentiation+++GO:0009791///post-embryonic development+++GO:0001756///somitogenesis+++GO:0007275///multicellular organism development+++GO:0021915///neural tube development+++GO:0003148///outflow tract septum morphogenesis+++GO:0007399///nervous system development+++GO:0001974///blood vessel remodeling+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0003151///outflow tract morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0007411///axon guidance+++GO:1905312///positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching","semaphorin 3C","[SEM3C_HUMAN|Reviewed]RecName: Full=Semaphorin-3C; AltName: Full=Semaphorin-E; Short=Sema E; Flags: Precursor;+++[F2Z2Y0_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000395398};+++[F8WEP9_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000393825};+++[Q75L25_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS07489.1}; Flags: Fragment;+++[Q75MX0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS00351.1}; Flags: Fragment;"]
[10513,"'APPBP2'",626,544,539,569.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005875///microtubule associated complex+++GO:0005874///microtubule+++GO:0005634///nucleus","GO:0003777///microtubule motor activity+++GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0046907///intracellular transport","amyloid beta precursor protein binding protein 2","[APBP2_HUMAN|Reviewed]RecName: Full=Amyloid protein-binding protein 2; AltName: Full=Amyloid beta precursor protein-binding protein 2; Short=APP-BP2; AltName: Full=Protein interacting with APP tail 1;+++[A0A024QZ47_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW51407.1};+++[K7EIZ9_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000464962}; Flags: Fragment;+++[K7EN61_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000466802};+++[K7ENN3_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000467025};"]
[10514,"'MYBBP1A'",1146,1226,1169,1180.33333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0042564///NLS-dependent protein nuclear import complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0043565///sequence-specific DNA binding+++GO:0070888///E-box binding+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:2000210///positive regulation of anoikis+++GO:0042254///ribosome biogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0001649///osteoblast differentiation+++GO:0071158///positive regulation of cell cycle arrest+++GO:0032922///circadian regulation of gene expression+++GO:0022904///respiratory electron transport chain+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0048511///rhythmic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042149///cellular response to glucose starvation+++GO:0045815///positive regulation of gene expression, epigenetic","MYB binding protein 1a","[MBB1A_HUMAN|Reviewed]RecName: Full=Myb-binding protein 1A;+++[I3L1L3_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000458919}; Flags: Fragment;+++[I3L2H8_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000459692}; Flags: Fragment;+++[I3L311_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000460087}; Flags: Fragment;"]
[10516,"'FBLN5'",8880,7062,6778,7573.33333333333,null,"H00821///Age-related macular degeneration+++H00557///Cutis laxa",null,null,"GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:0031012///extracellular matrix+++GO:0071953///elastic fiber+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0008022///protein C-terminus binding+++GO:0042803///protein homodimerization activity+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0005509///calcium ion binding","GO:2000121///regulation of removal of superoxide radicals+++GO:0048251///elastic fiber assembly+++GO:0030198///extracellular matrix organization+++GO:0034394///protein localization to cell surface+++GO:0007160///cell-matrix adhesion+++GO:0007155///cell adhesion+++GO:0001558///regulation of cell growth+++GO:0046903///secretion","fibulin 5","[FBLN5_HUMAN|Reviewed]RecName: Full=Fibulin-5; Short=FIBL-5; AltName: Full=Developmental arteries and neural crest EGF-like protein; Short=Dance; AltName: Full=Urine p50 protein; Short=UP50; Flags: Precursor;+++[A0A024R6G3_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_b {ECO:0000313|EMBL:EAW81467.1}; SubName: Full=Testis tissue sperm-binding protein Li 75n {ECO:0000313|EMBL:AEE61295.1};+++[G3V2P8_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000450787};+++[G3V329_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451002};+++[G3V3Y2_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451486}; Flags: Fragment;+++[G3V4U0_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451982};+++[G3XA98_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_a {ECO:0000313|EMBL:EAW81465.1}; SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000267620};"]
[10517,"'FBXW10'",1,4,0,1.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0000209///protein polyubiquitination","F-box and WD repeat domain containing 10","[FBW10_HUMAN|Reviewed]RecName: Full=F-box/WD repeat-containing protein 10; AltName: Full=F-box and WD-40 domain-containing protein 10; AltName: Full=Ubiquitin ligase-specificity factor;+++[J3QLH9_HUMAN|Unreviewed]SubName: Full=F-box/WD repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000463552};"]
[10518,"'CIB2'",118,99,110,109,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0042383///sarcolemma+++GO:0005737///cytoplasm+++GO:0032437///cuticular plate+++GO:0005929///cilium+++GO:0005886///plasma membrane+++GO:0005927///muscle tendon junction+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0001750///photoreceptor outer segment+++GO:0016020///membrane+++GO:0072562///blood microparticle+++GO:0032420///stereocilium+++GO:0001917///photoreceptor inner segment","GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0071318///cellular response to ATP+++GO:0055074///calcium ion homeostasis+++GO:0045494///photoreceptor cell maintenance+++GO:0007204///positive regulation of cytosolic calcium ion concentration","calcium and integrin binding family member 2","[CIB2_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding family member 2; AltName: Full=Kinase-interacting protein 2; Short=KIP 2;+++[A0A2R8Y4Y2_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000494155}; Flags: Fragment;+++[H0YKC8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452752};+++[H0YKX8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452980}; Flags: Fragment;+++[H0YLL7_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453256}; Flags: Fragment;+++[H0YLX3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453377}; Flags: Fragment;+++[H0YML3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453654}; Flags: Fragment;+++[H0YND4_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453963};"]
[10519,"'CIB1'",844,692,849,795,"04137///Mitophagy - animal+++04360///Axon guidance+++04140///Autophagy - animal","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016324///apical plasma membrane+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0032433///filopodium tip+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0031982///vesicle+++GO:0030424///axon+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030426///growth cone+++GO:0005815///microtubule organizing center+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0032587///ruffle membrane+++GO:0043025///neuronal cell body+++GO:0071944///cell periphery","GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017016///Ras GTPase binding+++GO:0005509///calcium ion binding+++GO:0044325///ion channel binding+++GO:0043495///protein membrane anchor+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding","GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0071363///cellular response to growth factor stimulus+++GO:0010977///negative regulation of neuron projection development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0007155///cell adhesion+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0042127///regulation of cell proliferation+++GO:0001525///angiogenesis+++GO:0007286///spermatid development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:2000256///positive regulation of male germ cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0001934///positive regulation of protein phosphorylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0051301///cell division+++GO:0030307///positive regulation of cell growth+++GO:0030220///platelet formation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0002931///response to ischemia+++GO:0031122///cytoplasmic microtubule organization+++GO:0008285///negative regulation of cell proliferation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007113///endomitotic cell cycle+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0006302///double-strand break repair+++GO:0007049///cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043085///positive regulation of catalytic activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0051302///regulation of cell division+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0008284///positive regulation of cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006915///apoptotic process+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007283///spermatogenesis","calcium and integrin binding 1","[CIB1_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding protein 1; Short=CIB; AltName: Full=Calcium- and integrin-binding protein; Short=CIBP; AltName: Full=Calmyrin; AltName: Full=DNA-PKcs-interacting protein; AltName: Full=Kinase-interacting protein; Short=KIP; AltName: Full=SNK-interacting protein 2-28; Short=SIP2-28;+++[A0A140VK09_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 9 {ECO:0000313|EMBL:AEE61146.1};"]
[1052,"'CEBPD'",636,699,612,649,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II","CCAAT enhancer binding protein delta","[CEBPD_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein delta; Short=C/EBP delta; AltName: Full=Nuclear factor NF-IL6-beta {ECO:0000303|PubMed:1741402}; Short=NF-IL6-beta {ECO:0000303|PubMed:1741402};+++[Q504X4_HUMAN|Unreviewed]SubName: Full=CEBPD protein {ECO:0000313|EMBL:AAH94715.1};"]
[10520,"'ZNF211'",179,160,145,161.333333333333,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 211","[ZN211_HUMAN|Reviewed]RecName: Full=Zinc finger protein 211; AltName: Full=Zinc finger protein C2H2-25;+++[A0A0A0MTK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442601};+++[F5GY70_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000440793};+++[F5H771_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442740};+++[H0Y3T8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000384436}; Flags: Fragment;"]
[10521,"'DDX17'",3804,4063,3825,3897.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005730///nucleolus","GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008186///RNA-dependent ATPase activity+++GO:0003724///RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding","GO:0045445///myoblast differentiation+++GO:0006396///RNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0010586///miRNA metabolic process+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031047///gene silencing by RNA+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0002376///immune system process+++GO:0030521///androgen receptor signaling pathway+++GO:0001837///epithelial to mesenchymal transition+++GO:0051607///defense response to virus+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006364///rRNA processing+++GO:0006357///regulation of transcription by RNA polymerase II","DEAD-box helicase 17","[DDX17_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX17; EC=3.6.4.13; AltName: Full=DEAD box protein 17; AltName: Full=DEAD box protein p72; AltName: Full=DEAD box protein p82 {ECO:0000303|PubMed:19995069}; AltName: Full=RNA-dependent helicase p72;+++[A0A0U1RQJ0_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000489029}; Flags: Fragment;+++[A0A1W2PQ51_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000491776};+++[A0A1X7SBZ2_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000385536};+++[Q59F66_HUMAN|Unreviewed]SubName: Full=DEAD box polypeptide 17 isoform p82 variant {ECO:0000313|EMBL:BAD92832.1}; Flags: Fragment;"]
[10522,"'DEAF1'",1759,1940,1693,1797.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center+++GO:0005667///transcription factor complex+++GO:0005902///microvillus+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0016605///PML body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0001931///uropod","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding+++GO:0030544///Hsp70 protein binding","GO:0007275///multicellular organism development+++GO:0050900///leukocyte migration+++GO:0009653///anatomical structure morphogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0006935///chemotaxis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050863///regulation of T cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0050901///leukocyte tethering or rolling+++GO:0006955///immune response+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007281///germ cell development+++GO:0001843///neural tube closure+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0006366///transcription by RNA polymerase II+++GO:2000406///positive regulation of T cell migration+++GO:0006968///cellular defense response+++GO:0008542///visual learning+++GO:0042742///defense response to bacterium+++GO:0048706///embryonic skeletal system development+++GO:0007163///establishment or maintenance of cell polarity+++GO:2000404///regulation of T cell migration+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0032609///interferon-gamma production+++GO:0042535///positive regulation of tumor necrosis factor biosynthetic process+++GO:0001662///behavioral fear response","DEAF1 transcription factor","[DEAF1_HUMAN|Reviewed]RecName: Full=Deformed epidermal autoregulatory factor 1 homolog; AltName: Full=Nuclear DEAF-1-related transcriptional regulator; Short=NUDR; AltName: Full=Suppressin; AltName: Full=Zinc finger MYND domain-containing protein 5;+++[A0A0J9YWD6_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000487909}; Flags: Fragment;+++[A0A0J9YX80_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488285}; Flags: Fragment;+++[A0A0J9YXA4_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488313}; Flags: Fragment;+++[C9JUK7_HUMAN|Unreviewed]SubName: Full=Leukosialin {ECO:0000313|Ensembl:ENSP00000412907}; Flags: Fragment;+++[H0YCH1_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000431563}; Flags: Fragment;+++[H0YCY2_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000432518}; Flags: Fragment;"]
[10523,"'CHERP'",2021,2422,2091,2178,"03040///Spliceosome",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005623///cell+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0044325///ion channel binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0006874///cellular calcium ion homeostasis+++GO:0007399///nervous system development+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0008285///negative regulation of cell proliferation+++GO:0051209///release of sequestered calcium ion into cytosol","calcium homeostasis endoplasmic reticulum protein","[CHERP_HUMAN|Reviewed]RecName: Full=Calcium homeostasis endoplasmic reticulum protein; AltName: Full=ERPROT 213-21; AltName: Full=SR-related CTD-associated factor 6;+++[J3QK89_HUMAN|Unreviewed]SubName: Full=Calcium homeostasis endoplasmic reticulum protein {ECO:0000313|Ensembl:ENSP00000198939};"]
[10524,"'KAT5'",556.23,594,578.28,576.17,"05166///HTLV-I infection","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0000123///histone acetyltransferase complex+++GO:0005730///nucleolus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000790///nuclear chromatin+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0000812///Swr1 complex","GO:0070491///repressing transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0016740///transferase activity+++GO:0042393///histone binding+++GO:0005515///protein binding+++GO:0010485///H4 histone acetyltransferase activity+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0016407///acetyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004402///histone acetyltransferase activity","GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1901985///positive regulation of protein acetylation+++GO:0016032///viral process+++GO:0006302///double-strand break repair+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0000729///DNA double-strand break processing+++GO:0016573///histone acetylation+++GO:0040008///regulation of growth+++GO:0032703///negative regulation of interleukin-2 production+++GO:0010212///response to ionizing radiation+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0071392///cellular response to estradiol stimulus+++GO:0006260///DNA replication+++GO:0030521///androgen receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","lysine acetyltransferase 5","[KAT5_HUMAN|Reviewed]RecName: Full=Histone acetyltransferase KAT5; EC=2.3.1.48 {ECO:0000269|PubMed:10096020, ECO:0000269|PubMed:12468530, ECO:0000269|PubMed:29040603}; AltName: Full=60 kDa Tat-interactive protein; Short=Tip60 {ECO:0000303|PubMed:10096020, ECO:0000303|PubMed:11416127, ECO:0000303|PubMed:12801643, ECO:0000303|PubMed:29040603}; AltName: Full=Histone acetyltransferase HTATIP; Short=HIV-1 Tat interactive protein; AltName: Full=Lysine acetyltransferase 5; AltName: Full=cPLA(2)-interacting protein;+++[A0A024R597_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[A0A024R5E8_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PJI1_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PMG8_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000434993}; Flags: Fragment;+++[E9PRL6_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436012}; Flags: Fragment;+++[E9PRM3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436000}; Flags: Fragment;+++[E9PRS1_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435939}; Flags: Fragment;+++[H0YEG3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435766}; Flags: Fragment;+++[H0YEP0_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436247}; Flags: Fragment;"]
[10525,"'HYOU1'",5823,6115,6040,5992.66666666667,"04141///Protein processing in endoplasmic reticulum","H00118///Congenital disorders of glycosylation (CDG) type I+++H00770///Congenital myasthenic syndrome","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0016020///membrane+++GO:0071682///endocytic vesicle lumen+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005925///focal adhesion","GO:0051087///chaperone binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0036498///IRE1-mediated unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006898///receptor-mediated endocytosis+++GO:0043066///negative regulation of apoptotic process+++GO:1903382///negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway+++GO:0071456///cellular response to hypoxia+++GO:0002931///response to ischemia+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway","hypoxia up-regulated 1","[HYOU1_HUMAN|Reviewed]RecName: Full=Hypoxia up-regulated protein 1; AltName: Full=150 kDa oxygen-regulated protein; Short=ORP-150; AltName: Full=170 kDa glucose-regulated protein; Short=GRP-170; Flags: Precursor;+++[A0A024R3G0_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated 1, isoform CRA_a {ECO:0000313|EMBL:EAW67441.1};+++[A0A087WW13_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000479845}; Flags: Fragment;+++[A0A087WWI4_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000480248};+++[A0A087X054_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000483106};+++[A0A087X214_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000484622}; Flags: Fragment;+++[B3KXH0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45395 fis, clone BRHIP3027191, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAG54482.1};+++[B7Z602_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59408, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13088.1};+++[B7Z766_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54564, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13502.1};+++[E9PJ21_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000431874}; Flags: Fragment;+++[J3KSR2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000464026};+++[J3KTF1_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000462951}; Flags: Fragment;+++[J3QL06_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463318}; Flags: Fragment;+++[J3QLE9_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463515}; Flags: Fragment;+++[J3QQH7_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463742}; Flags: Fragment;+++[K7EQK2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000467866};+++[Q05D91_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH17726.1}; Flags: Fragment;+++[Q6IN67_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH72436.1};+++[Q9BST8_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH04560.1}; SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000482199};"]
[10526,"'IPO8'",482,427,443,450.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005623///cell+++GO:0005635///nuclear envelope","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0060964///regulation of gene silencing by miRNA+++GO:0006886///intracellular protein transport+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction","importin 8","[IPO8_HUMAN|Reviewed]RecName: Full=Importin-8; Short=Imp8; AltName: Full=Ran-binding protein 8; Short=RanBP8;+++[A0A087WXH2_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000481026}; Flags: Fragment;+++[F5GXT5_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000440979}; Flags: Fragment;+++[F5H009_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000444050}; Flags: Fragment;+++[F5H244_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439556}; Flags: Fragment;+++[F5H292_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439413}; Flags: Fragment;+++[F5H2I3_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446254}; Flags: Fragment;+++[F5H815_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000443789};+++[H0YH64_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446232}; Flags: Fragment;"]
[10527,"'IPO7'",1350,1214,1316,1293.33333333333,"04013///MAPK signaling pathway - fly",{"$nulls":3},"GO:0016020///membrane+++GO:0005623///cell+++GO:0005654///nucleoplasm+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005643///nuclear pore","GO:0008536///Ran GTPase binding+++GO:0008565///protein transporter activity+++GO:0042393///histone binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0030695///GTPase regulator activity","GO:0045087///innate immune response+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process","importin 7","[IPO7_HUMAN|Reviewed]RecName: Full=Importin-7; Short=Imp7; AltName: Full=Ran-binding protein 7; Short=RanBP7;+++[B3KNG9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14581 fis, clone NT2RM4001382, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51331.1}; SubName: Full=cDNA FLJ14986 fis, clone Y79AA1000784, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51391.1};+++[E9PLB2_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000435235}; Flags: Fragment;+++[E9PLJ0_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000433313};+++[L8E8A9_HUMAN|Unreviewed]SubName: Full=Alternative protein IPO7 {ECO:0000313|EMBL:CCQ43354.1};"]
[10528,"'NOP56'",1099,1090,1064,1084.33333333333,"03008///Ribosome biogenesis in eukaryotes","H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0031428///box C/D snoRNP complex+++GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:1990226///histone methyltransferase binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis","NOP56 ribonucleoprotein","[NOP56_HUMAN|Reviewed]RecName: Full=Nucleolar protein 56; AltName: Full=Nucleolar protein 5A;+++[A0PJ92_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH18421.1}; Flags: Fragment;+++[H0Y653_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000403199}; Flags: Fragment;+++[H0YDU4_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000434317}; Flags: Fragment;+++[Q5JXT2_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000388497}; Flags: Fragment;+++[Q9BSN3_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH04937.1};"]
[10529,"'NEBL'",106,114,90,103.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0031005///filamin binding+++GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding+++GO:0008307///structural constituent of muscle+++GO:0005523///tropomyosin binding","GO:0071691///cardiac muscle thin filament assembly","nebulette","[NEBL_HUMAN|Reviewed]RecName: Full=Nebulette; AltName: Full=Actin-binding Z-disk protein;+++[A0A0U1RQY0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489224}; Flags: Fragment;+++[A0A0U1RRI4_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489545}; Flags: Fragment;+++[A0A0U1RRK0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489562}; Flags: Fragment;+++[B0YJ47_HUMAN|Unreviewed]SubName: Full=Nebulette variant 4 {ECO:0000313|EMBL:ACA06025.1};+++[Q2TBD1_HUMAN|Unreviewed]SubName: Full=NEBL protein {ECO:0000313|EMBL:AAI10453.1};+++[Q59FZ8_HUMAN|Unreviewed]SubName: Full=Nebulette non-muscle isoform variant {ECO:0000313|EMBL:BAD92548.1}; Flags: Fragment;+++[Q5JUU7_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000396512}; Flags: Fragment;+++[Q5JUU8_HUMAN|Unreviewed]SubName: Full=Nebulette variant 6 {ECO:0000313|EMBL:ACA06021.1};"]
[10531,"'PITRM1'",1882,2169,1941,1997.33333333333,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008047///enzyme activator activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity","GO:0043085///positive regulation of catalytic activity+++GO:0006508///proteolysis+++GO:0006626///protein targeting to mitochondrion","pitrilysin metallopeptidase 1","[PREP_HUMAN|Reviewed]RecName: Full=Presequence protease, mitochondrial {ECO:0000305|PubMed:16849325}; Short=hPreP {ECO:0000303|PubMed:16849325}; EC=3.4.24.- {ECO:0000269|PubMed:10360838, ECO:0000269|PubMed:16849325, ECO:0000269|PubMed:19196155, ECO:0000269|PubMed:24931469}; AltName: Full=Pitrilysin metalloproteinase 1 {ECO:0000303|PubMed:10360838}; Short=Metalloprotease 1 {ECO:0000303|PubMed:10360838}; Short=hMP1 {ECO:0000303|PubMed:10360838}; Flags: Precursor;+++[A0A0A0MRX9_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000370382};+++[B1APQ0_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000399307}; Flags: Fragment;+++[B1APQ1_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000402072}; Flags: Fragment;+++[H0Y4F7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000391526}; Flags: Fragment;+++[H0Y7L7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000413687}; Flags: Fragment;"]
[10533,"'ATG7'",304,302,290,298.666666666667,"04136///Autophagy - other+++04140///Autophagy - animal+++04138///Autophagy - yeast+++04216///Ferroptosis",{"$nulls":3},"GO:0005930///axoneme+++GO:0034774///secretory granule lumen+++GO:0000407///phagophore assembly site+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0030424///axon+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity+++GO:0019778///Atg12 activating enzyme activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019779///Atg8 activating enzyme activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0004839///ubiquitin activating enzyme activity","GO:0071315///cellular response to morphine+++GO:0006464///cellular protein modification process+++GO:0042752///regulation of circadian rhythm+++GO:0061025///membrane fusion+++GO:0006501///C-terminal protein lipidation+++GO:0016567///protein ubiquitination+++GO:0039521///suppression by virus of host autophagy+++GO:0000422///autophagy of mitochondrion+++GO:0051607///defense response to virus+++GO:0007568///aging+++GO:0031401///positive regulation of protein modification process+++GO:0045732///positive regulation of protein catabolic process+++GO:0060548///negative regulation of cell death+++GO:0043312///neutrophil degranulation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:1902617///response to fluoride+++GO:0090298///negative regulation of mitochondrial DNA replication+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0006995///cellular response to nitrogen starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0010508///positive regulation of autophagy+++GO:0031667///response to nutrient levels+++GO:1901214///regulation of neuron death+++GO:0016236///macroautophagy+++GO:0009749///response to glucose+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0044805///late nucleophagy+++GO:0071455///cellular response to hyperoxia+++GO:0000045///autophagosome assembly+++GO:0009267///cellular response to starvation+++GO:0061684///chaperone-mediated autophagy","autophagy related 7","[ATG7_HUMAN|Reviewed]RecName: Full=Ubiquitin-like modifier-activating enzyme ATG7; AltName: Full=ATG12-activating enzyme E1 ATG7; AltName: Full=Autophagy-related protein 7; Short=APG7-like; Short=hAGP7; AltName: Full=Ubiquitin-activating enzyme E1-like protein;+++[A0A024R2E9_HUMAN|Unreviewed]SubName: Full=ATG7 autophagy related 7 homolog (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW64097.1};+++[B3KQM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90740 fis, clone PLACE1011045, highly similar to Autophagy-related protein 7 {ECO:0000313|EMBL:BAG52088.1};+++[C9J415_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000411880}; Flags: Fragment;+++[C9JE55_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000416644}; Flags: Fragment;+++[C9JFF4_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000415223}; Flags: Fragment;+++[C9JGL2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000390547}; Flags: Fragment;+++[C9JKA3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389996}; Flags: Fragment;+++[C9JNU2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000408303}; Flags: Fragment;+++[F8WDY9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389012};+++[H7BZ92_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000388295}; Flags: Fragment;+++[H7C059_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000393075}; Flags: Fragment;+++[H7C2J8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000406398}; Flags: Fragment;+++[H7C2R3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000407340}; Flags: Fragment;+++[H7C369_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000409844}; Flags: Fragment;"]
[10534,"'SSSCA1'",292,267,277,278.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0030027///lamellipodium","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","Sjogren syndrome/scleroderma autoantigen 1","[SSA27_HUMAN|Reviewed]RecName: Full=Sjoegren syndrome/scleroderma autoantigen 1; AltName: Full=Autoantigen p27;+++[E9PK41_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000431666};+++[E9PN57_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000432938};+++[G3V1B8_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000434381}; SubName: Full=Sjogren's syndrome/scleroderma autoantigen 1, isoform CRA_b {ECO:0000313|EMBL:EAW74407.1};+++[H0YEB6_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435432}; Flags: Fragment;+++[H0YEK1_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435982}; Flags: Fragment;"]
[10535,"'RNASEH2A'",116,145,136,132.333333333333,"03030///DNA replication","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0032299///ribonuclease H2 complex+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin+++GO:0005667///transcription factor complex+++GO:0035976///transcription factor AP-1 complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0004518///nuclease activity+++GO:0004540///ribonuclease activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004519///endonuclease activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042493///response to drug+++GO:0001649///osteoblast differentiation+++GO:0034097///response to cytokine+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006401///RNA catabolic process+++GO:0001570///vasculogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0009987///cellular process+++GO:0010033///response to organic substance+++GO:0016070///RNA metabolic process+++GO:0001701///in utero embryonic development+++GO:0051591///response to cAMP+++GO:0009314///response to radiation+++GO:0043137///DNA replication, removal of RNA primer+++GO:0060136///embryonic process involved in female pregnancy+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032496///response to lipopolysaccharide+++GO:0046697///decidualization+++GO:0060716///labyrinthine layer blood vessel development+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0009612///response to mechanical stimulus+++GO:0006260///DNA replication+++GO:0071277///cellular response to calcium ion+++GO:0006298///mismatch repair+++GO:0001829///trophectodermal cell differentiation+++GO:0033687///osteoblast proliferation+++GO:0045597///positive regulation of cell differentiation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0051726///regulation of cell cycle+++GO:0032870///cellular response to hormone stimulus","ribonuclease H2 subunit A","[RNH2A_HUMAN|Reviewed]RecName: Full=Ribonuclease H2 subunit A; Short=RNase H2 subunit A; EC=3.1.26.4; AltName: Full=Aicardi-Goutieres syndrome 4 protein; Short=AGS4; AltName: Full=RNase H(35); AltName: Full=Ribonuclease HI large subunit; Short=RNase HI large subunit; AltName: Full=Ribonuclease HI subunit A;+++[A0A2R8Y606_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[A0A2R8Y658_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515}; Flags: Fragment;+++[Q6IBG3_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[Q6UQL6_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};"]
[10536,"'P3H3'",2723,2740,2551,2671.33333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:1902494///catalytic complex","GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0051213///dioxygenase activity+++GO:0019797///procollagen-proline 3-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0031418///L-ascorbic acid binding","GO:0032964///collagen biosynthetic process+++GO:0032963///collagen metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0055114///oxidation-reduction process","prolyl 3-hydroxylase 3","[P3H3_HUMAN|Reviewed]RecName: Full=Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318}; EC=1.14.11.7; AltName: Full=Leprecan-like protein 2 {ECO:0000303|PubMed:15063763}; AltName: Full=Protein B {ECO:0000303|PubMed:8723724}; Flags: Precursor;"]
[105369140,"'LOC105369140'",1,1,0,0.666666666666667,"00380///Tryptophan metabolism+++01100///Metabolic pathways",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin",null,"GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","neuroblastoma breakpoint family member 6-like protein","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369155,"'105369155'",3,4,3,3.33333333333333,{"$nulls":8},"[FBXL2_BOVIN|diamond]RecName: Full=F-box/LRR-repeat protein 2 {ECO:0000305}; AltName: Full=F-box and leucine-rich repeat protein 2 {ECO:0000305};"]
[105369189,"'LOC105369189'",2,1,1,1.33333333333333,{"$nulls":7},"uncharacterized LOC105369189","[CSP_PLACC|diamond]RecName: Full=Circumsporozoite protein; Short=CS; Flags: Precursor;+++[TMPSD_MOUSE|diamond]RecName: Full=Transmembrane protease serine 13; EC=3.4.21.-; AltName: Full=Membrane-type mosaic serine protease; Short=Mosaic serine protease;+++[YM012_HUMAN|diamond]RecName: Full=Uncharacterized protein DKFZp434B061;+++[YV020_HUMAN|diamond]RecName: Full=Putative uncharacterized protein LOC388882;+++[YV023_HUMAN|diamond]RecName: Full=Putative uncharacterized protein ENSP00000383309;"]
[105369199,"'LOC105369199'",1,1,0,0.666666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0030016///myofibril+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0034622///cellular protein-containing complex assembly+++GO:1903358///regulation of Golgi organization+++GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization","neuroblastoma breakpoint family member 6-like protein","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;"]
[105369201,"'LOC105369201'",38,62,56,52,{"$nulls":4},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0042803///protein homodimerization activity",null,"uncharacterized LOC105369201","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369205,"'LOC105369205'",25,11,9,15,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"uncharacterized LOC105369205","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369214,"'LOC105369214'",0,0,2,0.666666666666667,{"$nulls":7},"uncharacterized LOC105369214","[Q9H5V2_HUMAN|Unreviewed]SubName: Full=cDNA: FLJ23003 fis, clone LNG00331 {ECO:0000313|EMBL:BAB15517.1};"]
[105369591,"'LOC105369591'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005887///integral component of plasma membrane",null,"GO:0007224///smoothened signaling pathway+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0007520///myoblast fusion+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0045663///positive regulation of myoblast differentiation+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0021987///cerebral cortex development+++GO:0043497///regulation of protein heterodimerization activity+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045666///positive regulation of neuron differentiation+++GO:0001708///cell fate specification+++GO:0002088///lens development in camera-type eye+++GO:0010172///embryonic body morphogenesis+++GO:0009952///anterior/posterior pattern specification","uncharacterized LOC105369591","[F7AQJ7_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000010025};"]
[105369669,"'LOC105369669'",0,2,3,1.66666666666667,"04217///Necroptosis+++05034///Alcoholism+++04137///Mitophagy - animal+++05322///Systemic lupus erythematosus+++04140///Autophagy - animal",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006352///DNA-templated transcription, initiation+++GO:0006342///chromatin silencing+++GO:0006334///nucleosome assembly","uncharacterized LOC105369669","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[H2AJ_BOVIN|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_HUMAN|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_MACFA|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_MOUSE|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_RAT|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H4_HUMAN|diamond]RecName: Full=Histone H4;+++[H4_MACFA|diamond]RecName: Full=Histone H4;+++[H4_PONAB|diamond]RecName: Full=Histone H4;+++[H4_URECA|diamond]RecName: Full=Histone H4;+++[H4_XENTR|diamond]RecName: Full=Histone H4;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369869,"'LOC105369869'",1,3,3,2.33333333333333,{"$nulls":4},"GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0043005///neuron projection+++GO:0098793///presynapse+++GO:0070062///extracellular exosome+++GO:0045211///postsynaptic membrane+++GO:0045202///synapse+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0005923///bicellular tight junction+++GO:0005622///intracellular","GO:0097016///L27 domain binding","GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0048489///synaptic vesicle transport+++GO:0048839///inner ear development+++GO:0007269///neurotransmitter secretion+++GO:1903361///protein localization to basolateral plasma membrane+++GO:0065003///protein-containing complex assembly+++GO:0006887///exocytosis+++GO:0015031///protein transport","uncharacterized LOC105369869","[LIN7A_BOVIN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A;+++[LIN7A_HUMAN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=hLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Tax interaction protein 33; Short=TIP-33; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_MOUSE|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=mLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_RAT|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;"]
[105369914,"'LOC105369914'",3,8,2,4.33333333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","translation initiation factor IF-2-like","[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[PKP2_HUMAN|diamond]RecName: Full=Plakophilin-2;+++[TMCC1_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 1;+++[TMCC2_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 2; AltName: Full=Cerebral protein 11;+++[TMCC2_MOUSE|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 2;+++[TMCC3_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domain protein 3;+++[TMCC3_MOUSE|diamond]RecName: Full=Transmembrane and coiled-coil domain protein 3;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[10537,"'UBD'",4,4,1,3,{"$nulls":4},"GO:0016235///aggresome+++GO:0045211///postsynaptic membrane+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0030054///cell junction+++GO:0098793///presynapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0038037///G protein-coupled receptor dimeric complex+++GO:0038039///G protein-coupled receptor heterodimeric complex+++GO:0042734///presynaptic membrane+++GO:0016020///membrane+++GO:0098982///GABA-ergic synapse+++GO:0005737///cytoplasm","GO:0099579///G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential+++GO:0005515///protein binding+++GO:0070628///proteasome binding+++GO:0004965///G protein-coupled GABA receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0006508///proteolysis+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0032446///protein modification by small protein conjugation+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016567///protein ubiquitination+++GO:0034341///response to interferon-gamma+++GO:0043687///post-translational protein modification+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070842///aggresome assembly+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0034612///response to tumor necrosis factor+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","ubiquitin D","[UBD_HUMAN|Reviewed]RecName: Full=Ubiquitin D; AltName: Full=Diubiquitin; AltName: Full=Ubiquitin-like protein FAT10;+++[A0A0G2JH67_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77196.1}; SubName: Full=Ubiquitin D {ECO:0000313|Ensembl:ENSP00000373137};+++[A0A0G2JKF9_HUMAN|Unreviewed]SubName: Full=GABBR1 {ECO:0000313|EMBL:AQY76823.1}; SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000416731};+++[A0A140T9S4_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000412044};+++[A0A140TA42_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000448763};+++[A0A1U9X8S6_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77194.1};+++[C9J342_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417332}; Flags: Fragment;+++[C9JZG6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419755}; Flags: Fragment;+++[F8WAS6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417663};+++[F8WAV2_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417478};+++[F8WDC0_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000420602};+++[F8WF38_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419356};"]
[105370045,"'105370045'",49,42,55,48.6666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding","GO:0061572///actin filament bundle organization+++GO:0061181///regulation of chondrocyte development",null,"[RFLA_HUMAN|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;+++[RFLA_MOUSE|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A {ECO:0000303|PubMed:21709252}; Short=RefilinA;"]
[105370092,"'LOC105370092'",21,53,31,35,{"$nulls":7},"uncharacterized LOC105370092","[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;"]
[105370399,"'LOC105370399'",0,2,1,1,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"uncharacterized LOC105370399","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370579,"'LOC105370579'",2,3,1,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC105370579","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370641,"'LOC105370641'",0,3,1,1.33333333333333,{"$nulls":7},"uncharacterized LOC105370641","[A0A146R4I4_FUNHE|diamond]SubName: Full=HCG1778991 {ECO:0000313|EMBL:JAQ63352.1}; Flags: Fragment;+++[A0A287ANQ5_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000045530};+++[A0A287BB99_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000053389};+++[A0A2G8KAB5_STIJA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PIK44956.1};+++[L8IFV1_9CETA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELR54012.1}; Flags: Fragment;"]
[105370687,"'LOC105370687'",29,29,25,27.6666666666667,"03013///RNA transport+++04214///Apoptosis - fly",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0008135///translation factor activity, RNA binding+++GO:0045296///cadherin binding+++GO:0003924///GTPase activity+++GO:0071074///eukaryotic initiation factor eIF2 binding+++GO:0003723///RNA binding+++GO:0005525///GTP binding+++GO:0003743///translation initiation factor activity","GO:0006446///regulation of translational initiation+++GO:0001731///formation of translation preinitiation complex+++GO:0006413///translational initiation+++GO:0090630///activation of GTPase activity","uncharacterized LOC105370687","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[IF5_DROME|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_HUMAN|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_MOUSE|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_PONAB|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_RAT|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370705,"'LOC105370705'",0,0,1,0.333333333333333,"03015///mRNA surveillance pathway+++03013///RNA transport+++03040///Spliceosome",null,"M00430///Exon junction complex (EJC)",null,"GO:0061574///ASAP complex+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0019899///enzyme binding+++GO:0003676///nucleic acid binding+++GO:0016887///ATPase activity+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0030218///erythrocyte differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0030263///apoptotic chromosome condensation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0045657///positive regulation of monocyte differentiation+++GO:0006397///mRNA processing","collagen alpha-2(I) chain-like","[ACINU_HUMAN|diamond]RecName: Full=Apoptotic chromatin condensation inducer in the nucleus; Short=Acinus;+++[ACINU_MOUSE|diamond]RecName: Full=Apoptotic chromatin condensation inducer in the nucleus; Short=Acinus;+++[CN119_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf119;+++[CN119_MOUSE|diamond]RecName: Full=Uncharacterized protein C14orf119 homolog;+++[LMLN2_HUMAN|diamond]RecName: Full=Leishmanolysin-like peptidase 2 {ECO:0000305}; EC=3.4.24.- {ECO:0000250|UniProtKB:Q9VH19}; Flags: Precursor;"]
[105370708,"'LOC105370708'",6,6,4,5.33333333333333,{"$nulls":7},"uncharacterized LOC105370708"]
[105370748,"'105370748'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0072686///mitotic spindle+++GO:0032580///Golgi cisterna membrane+++GO:0000922///spindle pole+++GO:0000139///Golgi membrane+++GO:0000137///Golgi cis cisterna+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0005794///Golgi apparatus","GO:0045296///cadherin binding+++GO:0019905///syntaxin binding+++GO:0042802///identical protein binding+++GO:0061676///importin-alpha family protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding","GO:0051289///protein homotetramerization+++GO:0090307///mitotic spindle assembly+++GO:0007098///centrosome cycle+++GO:0006486///protein glycosylation+++GO:0010507///negative regulation of autophagy+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0008356///asymmetric cell division+++GO:0060050///positive regulation of protein glycosylation+++GO:0032091///negative regulation of protein binding+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0051225///spindle assembly+++GO:0007020///microtubule nucleation+++GO:0048208///COPII vesicle coating+++GO:0090161///Golgi ribbon formation+++GO:0090306///spindle assembly involved in meiosis+++GO:0090166///Golgi disassembly",null,"[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[GOGA2_MOUSE|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein; Short=GM130 {ECO:0000303|PubMed:21552007, ECO:0000303|PubMed:26165940};+++[GOGA2_RAT|diamond]RecName: Full=Golgin subfamily A member 2 {ECO:0000305}; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8557739}; Short=GM130 {ECO:0000303|PubMed:8557739};"]
[105370849,"'LOC105370849'",0,2,1,1,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0000137///Golgi cis cisterna+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0000139///Golgi membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0000922///spindle pole+++GO:0072686///mitotic spindle+++GO:0032580///Golgi cisterna membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane","GO:0019905///syntaxin binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0019901///protein kinase binding+++GO:0045296///cadherin binding+++GO:0061676///importin-alpha family protein binding","GO:0090166///Golgi disassembly+++GO:0010507///negative regulation of autophagy+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0051289///protein homotetramerization+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048208///COPII vesicle coating+++GO:0060050///positive regulation of protein glycosylation+++GO:0006486///protein glycosylation+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0007020///microtubule nucleation+++GO:0090306///spindle assembly involved in meiosis+++GO:0032091///negative regulation of protein binding+++GO:0008356///asymmetric cell division+++GO:0090161///Golgi ribbon formation+++GO:0090307///mitotic spindle assembly","golgin subfamily A member 2-like","[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8A; AltName: Full=88 kDa Golgi matrix protein; Short=GM88; AltName: Full=GM88 autoantigen;+++[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[GOGA2_MOUSE|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein; Short=GM130 {ECO:0000303|PubMed:21552007, ECO:0000303|PubMed:26165940};+++[GOGA2_RAT|diamond]RecName: Full=Golgin subfamily A member 2 {ECO:0000305}; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8557739}; Short=GM130 {ECO:0000303|PubMed:8557739};+++[YO027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ45275, mitochondrial; Flags: Precursor;"]
[105370940,"'LOC105370940'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC105370940"]
[105370980,"'LOC105370980'",0,1,0,0.333333333333333,{"$nulls":7},"putative uncharacterized protein UNQ9370/PRO34162","[YO001_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein UNQ9370/PRO34162;"]
[105371063,"'LOC105371063'",1,0,0.4,0.466666666666667,{"$nulls":7},"putative uncharacterized protein encoded by LINC00596","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105371095,"'LOC105371095'",0,1,0,0.333333333333333,{"$nulls":7},"collagen alpha-3(IX) chain-like","[PAWR_HUMAN|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_MOUSE|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_RAT|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4; AltName: Full=Transcriptional repressor Par-4-like protein PAWR;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;"]
[105371242,"'PPIAL4H'",4,0,0,1.33333333333333,{"$nulls":4},"GO:0008021///synaptic vesicle+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0042470///melanosome+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031201///SNARE complex","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0019905///syntaxin binding","GO:0045732///positive regulation of protein catabolic process+++GO:0016192///vesicle-mediated transport+++GO:0006457///protein folding+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0015031///protein transport+++GO:0048280///vesicle fusion with Golgi apparatus","peptidylprolyl isomerase A like 4H","[A0A075B767_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[105371371,"'LOC105371371'",0,2,0,0.666666666666667,{"$nulls":5},"GO:0008083///growth factor activity","GO:0007275///multicellular organism development+++GO:0043065///positive regulation of apoptotic process+++GO:0030154///cell differentiation+++GO:0030308///negative regulation of cell growth","uncharacterized LOC105371371","[OSGI1_HUMAN|diamond]RecName: Full=Oxidative stress-induced growth inhibitor 1; AltName: Full=Ovary, kidney and liver protein 38; Short=huOKL38; AltName: Full=Pregnancy-induced growth inhibitor OKL38;"]
[105371419,"'LOC105371419'",3,0,2,1.66666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity",null,"uncharacterized LOC105371419","[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YN010_HUMAN|diamond]RecName: Full=Putative uncharacterized protein PRO2829; Flags: Precursor;"]
[105371566,"'LOC105371566'",0,1,1,0.666666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0016459///myosin complex+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0032420///stereocilium","GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0046872///metal ion binding+++GO:0003774///motor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0005524///ATP binding+++GO:0005516///calmodulin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0042472///inner ear morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007626///locomotory behavior+++GO:0006351///transcription, DNA-templated+++GO:0007605///sensory perception of sound","uncharacterized LOC105371566","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[MYO15_HUMAN|diamond]RecName: Full=Unconventional myosin-XV; AltName: Full=Unconventional myosin-15;+++[PKP2_HUMAN|diamond]RecName: Full=Plakophilin-2;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN429_HUMAN|diamond]RecName: Full=Zinc finger protein 429;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105371763,"'LOC105371763'",19,20,15,18,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0035812///renal sodium excretion+++GO:2001161///negative regulation of histone H3-K79 methylation+++GO:0035811///negative regulation of urine volume+++GO:0010765///positive regulation of sodium ion transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036359///renal potassium excretion","uncharacterized LOC105371763","[AF10_HUMAN|diamond]RecName: Full=Protein AF-10 {ECO:0000305}; AltName: Full=ALL1-fused gene from chromosome 10 protein;+++[AF10_MOUSE|diamond]RecName: Full=Protein AF-10 {ECO:0000305};+++[AF17_HUMAN|diamond]RecName: Full=Protein AF-17; AltName: Full=ALL1-fused gene from chromosome 17 protein;+++[CISD3_HUMAN|diamond]RecName: Full=CDGSH iron-sulfur domain-containing protein 3, mitochondrial; AltName: Full=MitoNEET-related protein 2; Short=Miner2; AltName: Full=Mitochondrial inner NEET protein {ECO:0000303|PubMed:29259115}; Short=MiNT {ECO:0000303|PubMed:29259115}; Flags: Precursor;+++[YM2A_CAEEL|diamond]RecName: Full=Uncharacterized protein F54F2.2, isoform a;"]
[105371910,"'LOC105371910'",10,24,23,19,{"$nulls":4},"GO:0005829///cytosol","GO:0008732///L-allo-threonine aldolase activity","GO:0006545///glycine biosynthetic process+++GO:0006567///threonine catabolic process","uncharacterized LOC105371910","[A0A2U3XS95_LEPWE|diamond]SubName: Full=uncharacterized protein R102.4-like {ECO:0000313|RefSeq:XP_006734331.1};+++[A0A2Y9GBZ0_NEOSC|diamond]SubName: Full=probable low-specificity L-threonine aldolase 2 {ECO:0000313|RefSeq:XP_021536492.1};+++[F7D9Y6_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000005176};+++[G1M5J9_AILME|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000014617};+++[S9XGI9_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY86794.1};"]
[105371921,"'LOC105371921'",2,1,1,1.33333333333333,{"$nulls":7},"uncharacterized LOC105371921"]
[105371932,"'LOC105371932'",10,4,11,8.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0005524///ATP binding",null,"uncharacterized LOC105371932","[A0A2K5WEY0_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000035670};+++[A0A2K6C0W4_MACNE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000017314};"]
[105371944,"'LOC105371944'",0,1,2,1,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016328///lateral plasma membrane+++GO:0005874///microtubule+++GO:0005923///bicellular tight junction+++GO:0005912///adherens junction+++GO:0005813///centrosome","GO:0051087///chaperone binding+++GO:0048487///beta-tubulin binding+++GO:0005096///GTPase activator activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0031115///negative regulation of microtubule polymerization+++GO:0007023///post-chaperonin tubulin folding pathway+++GO:0034333///adherens junction assembly+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0070830///bicellular tight junction assembly+++GO:0006457///protein folding+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0000278///mitotic cell cycle+++GO:0007021///tubulin complex assembly","uncharacterized LOC105371944","[Q6ZPB7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26108 fis, clone SPL05107 {ECO:0000313|EMBL:BAC85197.1};"]
[105372204,"'LOC105372204'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC105372204"]
[105372269,"'LOC105372269'",7,10,1,6,{"$nulls":4},"GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004856///xylulokinase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004190///aspartic-type endopeptidase activity","GO:0042732///D-xylose metabolic process+++GO:0016032///viral process+++GO:0005997///xylulose metabolic process","endogenous retrovirus group K member 8 Gag polyprotein-like","[EN113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Env polyprotein; AltName: Full=EnvK5 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Env polyprotein; AltName: Full=EnvK3 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C19) envelope protein; AltName: Full=HERV-K_19q11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K_11q22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Env polyprotein; AltName: Full=EnvK2 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C7) envelope protein; AltName: Full=HERV-K(HML-2.HOM) envelope protein; AltName: Full=HERV-K108 envelope protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Env polyprotein; AltName: Full=EnvK6 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K115 envelope protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[GAK21_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 21 Gag polyprotein; AltName: Full=HERV-K_12q14.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[VP113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pro protein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[VPK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pro protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[XYLB_PONAB|diamond]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;"]
[105372280,"'GNG14'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005834///heterotrimeric G-protein complex","GO:0003924///GTPase activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","G protein subunit gamma 14","[GBG14_HUMAN|Reviewed]RecName: Full=Putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 {ECO:0000305};+++[A0A1W2PRI1_HUMAN|Unreviewed]SubName: Full=Putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 {ECO:0000313|Ensembl:ENSP00000492612};"]
[105372315,"'LOC105372315'",6,16,8,10,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane",null,null,"endogenous retrovirus group S71 member 1 Env polyprotein","[ENVT1_HUMAN|Reviewed]RecName: Full=Endogenous retrovirus group S71 member 1 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-T Env protein; AltName: Full=HERV-T_19q13.11 provirus ancestral Env polyprotein; Includes: RecName: Full=Surface protein; Short=SU; Includes: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[105372319,"'LOC105372319'",0,0,2,0.666666666666667,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated","zinc finger protein 430-like","[ZN626_HUMAN|diamond]RecName: Full=Zinc finger protein 626;+++[ZN695_HUMAN|diamond]RecName: Full=Zinc finger protein 695; AltName: Full=Zinc finger protein SBZF3;+++[ZN724_HUMAN|diamond]RecName: Full=Zinc finger protein 724 {ECO:0000305};+++[ZN737_HUMAN|diamond]RecName: Full=Zinc finger protein 737; AltName: Full=Zinc finger protein 102;+++[ZNF66_HUMAN|diamond]RecName: Full=Putative zinc finger protein 66; AltName: Full=Zinc finger protein 66 pseudogene;"]
[105372412,"'LOC105372412'",0,0,1,0.333333333333333,{"$nulls":7},"phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein-like","[A0A091DT05_FUKDA|diamond]SubName: Full=Interferon-inducible GTPase 5 {ECO:0000313|EMBL:KFO33613.1};+++[A0A2Y9P5V2_DELLE|diamond]SubName: Full=uncharacterized protein LOC111180525 {ECO:0000313|RefSeq:XP_022440616.1};+++[L9L7Y3_TUPCH|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELW71071.1};+++[M3Y5G8_MUSPF|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMPUP00000006569};+++[Q8WYX9_HUMAN|diamond]SubName: Full=Uncharacterized protein pp10122 {ECO:0000313|EMBL:AAL55824.1};+++[S9YW18_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY88250.1};"]
[105372704,"'LOC105372704'",0,3,1,1.33333333333333,{"$nulls":7},"uncharacterized LOC105372704"]
[105372824,"'LOC105372824'",8,24,25,19,{"$nulls":7},"uncharacterized LOC105372824","[A0A0B4J2C9_HUMAN|Unreviewed]SubName: Full=Pyridoxal kinase {ECO:0000313|Ensembl:ENSP00000479315};"]
[105372836,"'LOC105372836'",0,0,2,0.666666666666667,{"$nulls":7},"uncharacterized LOC105372836"]
[105372978,"'LINC01638'",4,5,4,4.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","long intergenic non-protein coding RNA 1638","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105373091,"'LOC105373091'",0,2,2,1.33333333333333,{"$nulls":7},"atherin-like"]
[105373102,"'LOC105373102'",28,30,39,32.3333333333333,"05166///HTLV-I infection+++04022///cGMP-PKG signaling pathway+++04020///Calcium signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04218///Cellular senescence+++04217///Necroptosis+++05016///Huntington's disease+++05012///Parkinson's disease","H01118///Progressive external ophthalmoplegia (PEO)+++H00469///Mitochondrial DNA depletion syndrome (MDS)",null,null,"GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane","GO:0008171///O-methyltransferase activity+++GO:0015207///adenine transmembrane transporter activity+++GO:0051213///dioxygenase activity+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0005471///ATP:ADP antiporter activity+++GO:0046872///metal ion binding","GO:0006626///protein targeting to mitochondrion+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0050796///regulation of insulin secretion+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0046732///active induction of host immune response by virus","uncharacterized LOC105373102","[ADT2_BOVIN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_HUMAN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=ADP,ATP carrier protein, fibroblast isoform; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_PONAB|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT3_BOVIN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_HUMAN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_PIG|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ASML_HUMAN|diamond]RecName: Full=N-acetylserotonin O-methyltransferase-like protein; Short=ASMTL; EC=2.1.1.-;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105373289,"'LOC105373289'",10,8,9,9,{"$nulls":7},"collagen alpha-1(III) chain-like"]
[105373311,"'LOC105373311'",44,24,39,35.6666666666667,{"$nulls":7},"translation initiation factor IF-2","[A0A1S3WQD2_ERIEU|diamond]SubName: Full=uncharacterized protein LOC107523152 {ECO:0000313|RefSeq:XP_016048578.1};+++[A0A2Y9FXY4_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC101348364 {ECO:0000313|RefSeq:XP_012411968.1};+++[A0A2Y9LSY7_DELLE|diamond]SubName: Full=LOW QUALITY PROTEIN: transcription factor Maf {ECO:0000313|RefSeq:XP_022412460.1};+++[B7Z208_HUMAN|diamond]SubName: Full=cDNA FLJ52622 {ECO:0000313|EMBL:BAH11694.1};"]
[105373314,"'LOC105373314'",2,1,1,1.33333333333333,{"$nulls":4},"GO:0005881///cytoplasmic microtubule+++GO:0043209///myelin sheath+++GO:0055037///recycling endosome+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0031594///neuromuscular junction","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton","GO:0007017///microtubule-based process+++GO:0050807///regulation of synapse organization","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1","[B3GNL_HUMAN|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-; AltName: Full=Beta-1,3-N-acetylglucosaminyltransferase 8; Short=BGnT-8; Short=Beta-1,3-Gn-T8; Short=Beta3Gn-T8;+++[B3GNL_MOUSE|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-;+++[B3GNL_RAT|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-;+++[TBA1A_CRIGR|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 2; AltName: Full=Alpha-tubulin II; AltName: Full=Tubulin alpha-2 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_MOUSE|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_PANTR|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 3; AltName: Full=Tubulin B-alpha-1; AltName: Full=Tubulin alpha-3 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_RAT|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Tubulin alpha-1 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA_BOMMO|diamond]RecName: Full=Tubulin alpha chain;"]
[105373381,"'LOC105373381'",1,0,0,0.333333333333333,{"$nulls":7},"extracellular matrix protein 2","[ECM2_BOVIN|diamond]RecName: Full=Extracellular matrix protein 2; Flags: Precursor;+++[ECM2_HUMAN|diamond]RecName: Full=Extracellular matrix protein 2; AltName: Full=Matrix glycoprotein SC1/ECM2; Flags: Precursor;+++[ECM2_MOUSE|diamond]RecName: Full=Extracellular matrix protein 2; AltName: Full=Tenonectin; Flags: Precursor;+++[PGS2_MOUSE|diamond]RecName: Full=Decorin; AltName: Full=Bone proteoglycan II; AltName: Full=PG-S2; AltName: Full=PG40; Flags: Precursor;+++[PGS2_RAT|diamond]RecName: Full=Decorin; AltName: Full=Bone proteoglycan II; AltName: Full=Dermatan sulfate proteoglycan-II; Short=DSPG; AltName: Full=PG-S2; AltName: Full=PG40; Flags: Precursor;"]
[105373759,"'LOC105373759'",2.31,8.03,5.02,5.12,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","uncharacterized LOC105373759","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105373780,"'LOC105373780'",11,18,8,12.3333333333333,{"$nulls":7},"proline-rich protein 18-like"]
[105373944,"'LOC105373944'",0,0,2,0.666666666666667,{"$nulls":7},"translation initiation factor IF-2-like","[A0A2U3ZY91_ODORO|diamond]SubName: Full=collagen alpha-1(I) chain-like {ECO:0000313|RefSeq:XP_012423953.1};"]
[105373989,"'LOC105373989'",144,106,94,114.666666666667,"04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery","GO:0005125///cytokine activity+++GO:0046789///host cell surface receptor binding+++GO:0005179///hormone activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0042803///protein homodimerization activity+++GO:0008083///growth factor activity","GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0042981///regulation of apoptotic process+++GO:0009267///cellular response to starvation+++GO:0030154///cell differentiation+++GO:0006952///defense response+++GO:0046676///negative regulation of insulin secretion+++GO:0048178///negative regulation of hepatocyte growth factor biosynthetic process+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0032924///activin receptor signaling pathway+++GO:0001541///ovarian follicle development+++GO:0045444///fat cell differentiation+++GO:0009611///response to wounding+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0048468///cell development+++GO:0043408///regulation of MAPK cascade+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0060279///positive regulation of ovulation+++GO:0044320///cellular response to leptin stimulus+++GO:0032869///cellular response to insulin stimulus+++GO:0048599///oocyte development","putative cuticle collagen 91","[INHBB_BOVIN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_HUMAN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_MOUSE|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_PIG|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_RAT|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;"]
[105374013,"'LOC105374013'",14,55,37,35.3333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0042788///polysomal ribosome","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044183///protein binding involved in protein folding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0042803///protein homodimerization activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0005198///structural molecule activity+++GO:0003676///nucleic acid binding","GO:0006915///apoptotic process+++GO:0002181///cytoplasmic translation+++GO:0010458///exit from mitosis+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0006310///DNA recombination+++GO:0016032///viral process+++GO:0021554///optic nerve development+++GO:0007093///mitotic cell cycle checkpoint+++GO:0015074///DNA integration+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0000027///ribosomal large subunit assembly+++GO:0006351///transcription, DNA-templated+++GO:0008616///queuosine biosynthetic process+++GO:0060041///retina development in camera-type eye","endogenous retrovirus group K member 5 Gag polyprotein","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GA113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Gag polyprotein; AltName: Full=HERV-K113 Gag protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Gag polyprotein; AltName: Full=HERV-K101 Gag protein; AltName: Full=HERV-K_22q11.21 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Gag polyprotein; AltName: Full=HERV-K(C7) Gag protein; AltName: Full=HERV-K(HML-2.HOM) Gag protein; AltName: Full=HERV-K108 Gag protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[PDCL3_BOVIN|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_HUMAN|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=HTPHLP; AltName: Full=PhPL3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_MOUSE|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_PONAB|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_RAT|diamond]RecName: Full=Phosducin-like protein 3;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Pol protein; AltName: Full=HERV-K(III) Pol protein; AltName: Full=HERV-K102 Pol protein; AltName: Full=HERV-K_1q22 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[RL24_BOVIN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_FELCA|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_HUMAN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=60S ribosomal protein L30; AltName: Full=Large ribosomal subunit protein eL24 {ECO:0000303|PubMed:24524803};+++[RL24_MACFA|diamond]RecName: Full=60S ribosomal protein L24;+++[RL24_MOUSE|diamond]RecName: Full=60S ribosomal protein L24;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[ZBT11_HUMAN|diamond]RecName: Full=Zinc finger and BTB domain-containing protein 11;"]
[105374089,"'LOC105374089'",1,3,1,1.66666666666667,{"$nulls":4},"GO:0031514///motile cilium+++GO:0097545///axonemal outer doublet","GO:0070840///dynein complex binding","GO:2000574///regulation of microtubule motor activity+++GO:0003341///cilium movement+++GO:0036159///inner dynein arm assembly","uncharacterized LOC105374089","[Q9NXP9_HUMAN|Unreviewed]SubName: Full=HCG1780190 {ECO:0000313|EMBL:EAW79365.1}; SubName: Full=cDNA FLJ20123 fis, clone COL06041 {ECO:0000313|EMBL:BAA90961.1};"]
[105374103,"'LOC105374103'",2,4.92,1,2.64,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity","GO:0015074///DNA integration","uncharacterized LOC105374103","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105374301,"'LOC105374301'",88,109,93.01,96.67,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005813///centrosome+++GO:0030289///protein phosphatase 4 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0019888///protein phosphatase regulator activity+++GO:0030674///protein binding, bridging","GO:0008380///RNA splicing+++GO:0006464///cellular protein modification process+++GO:0006397///mRNA processing+++GO:0010569///regulation of double-strand break repair via homologous recombination","mucin-1-like","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP4R2_CHICK|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_HUMAN|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_MOUSE|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_PONAB|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105374378,"'LOC105374378'",2,0,3,1.66666666666667,"00030///Pentose phosphate pathway+++03010///Ribosome",null,"M00178///Ribosome, bacteria","R02750///2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP+++R01051///ATP:D-ribose 5-phosphotransferase ATP + D-Ribose <=> ADP + D-Ribose 5-phosphate","GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit","GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0003735///structural constituent of ribosome+++GO:0019200///carbohydrate kinase activity+++GO:0004747///ribokinase activity","GO:0019303///D-ribose catabolic process+++GO:0070125///mitochondrial translational elongation+++GO:0046835///carbohydrate phosphorylation+++GO:0070126///mitochondrial translational termination+++GO:0006098///pentose-phosphate shunt","uncharacterized LOC105374378","[RBSK_HUMAN|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000269|PubMed:17585908};+++[RBSK_MOUSE|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000312|EMBL:AAH23339.1}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215};+++[RM33_ANOGA|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_BOVIN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_HUMAN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; AltName: Full=Mitochondrial large ribosomal subunit protein bL33m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[RM33_MOUSE|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_TETNG|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;"]
[105374811,"'LOC105374811'",0,0,1,0.333333333333333,"00230///Purine metabolism+++05166///HTLV-I infection+++00240///Pyrimidine metabolism+++03030///DNA replication+++03420///Nucleotide excision repair+++01100///Metabolic pathways+++03410///Base excision repair",null,"M00263///DNA polymerase epsilon complex","R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dTTP + DNA <=> Diphosphate + DNA+++R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dGTP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dCTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dATP + DNA <=> Diphosphate + DNA","GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0036126///sperm flagellum+++GO:0030425///dendrite+++GO:0061827///sperm head+++GO:0008622///epsilon DNA polymerase complex+++GO:0005886///plasma membrane+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0097225///sperm midpiece+++GO:0005654///nucleoplasm+++GO:0009986///cell surface+++GO:0044297///cell body","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0016496///substance P receptor activity+++GO:0046872///metal ion binding+++GO:0004995///tachykinin receptor activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046982///protein heterodimerization activity","GO:0002687///positive regulation of leukocyte migration+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0045777///positive regulation of blood pressure+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042713///sperm ejaculation+++GO:0007268///chemical synaptic transmission+++GO:0010193///response to ozone+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032197///transposition, RNA-mediated+++GO:0003051///angiotensin-mediated drinking behavior+++GO:0043117///positive regulation of vascular permeability+++GO:0045987///positive regulation of smooth muscle contraction+++GO:1902093///positive regulation of flagellated sperm motility+++GO:0007217///tachykinin receptor signaling pathway+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0045907///positive regulation of vasoconstriction+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0035094///response to nicotine+++GO:0035106///operant conditioning+++GO:0043966///histone H3 acetylation+++GO:0048266///behavioral response to pain+++GO:0045778///positive regulation of ossification+++GO:0009582///detection of abiotic stimulus+++GO:0032570///response to progesterone+++GO:0045471///response to ethanol+++GO:0002118///aggressive behavior+++GO:0046878///positive regulation of saliva secretion+++GO:0046887///positive regulation of hormone secretion+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006954///inflammatory response+++GO:0010996///response to auditory stimulus+++GO:0043278///response to morphine+++GO:0045760///positive regulation of action potential+++GO:0007616///long-term memory+++GO:0051496///positive regulation of stress fiber assembly+++GO:0010634///positive regulation of epithelial cell migration+++GO:0009408///response to heat+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0051602///response to electrical stimulus+++GO:0019233///sensory perception of pain+++GO:0008306///associative learning+++GO:0002526///acute inflammatory response+++GO:0006310///DNA recombination+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042755///eating behavior+++GO:0032355///response to estradiol+++GO:0014910///regulation of smooth muscle cell migration","uncharacterized LOC105374811","[DPOE4_BOVIN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4;+++[DPOE4_HUMAN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[DPOE4_MOUSE|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NFYC_BOVIN|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NFYC_RAT|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=CCAAT-binding transcription factor subunit C; Short=CBF-C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NK1R_CANLF|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_CAVPO|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_HUMAN|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_MOUSE|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_RAT|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;"]
[105375106,"'LOC105375106'",1,1,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030027///lamellipodium",null,"GO:0030335///positive regulation of cell migration+++GO:2000813///negative regulation of barbed-end actin filament capping+++GO:0051638///barbed-end actin filament uncapping+++GO:1902745///positive regulation of lamellipodium organization","uncharacterized LOC105375106","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[105375116,"'LOC105375116'",0,0,2,0.666666666666667,null,"H00968///Raine syndrome",null,null,"GO:0005794///Golgi apparatus+++GO:0005788///endoplasmic reticulum lumen+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0030145///manganese ion binding","GO:0030501///positive regulation of bone mineralization+++GO:0036179///osteoclast maturation+++GO:0051174///regulation of phosphorus metabolic process+++GO:0070166///enamel mineralization+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0031214///biomineral tissue development+++GO:0044267///cellular protein metabolic process+++GO:0071895///odontoblast differentiation+++GO:0040036///regulation of fibroblast growth factor receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0043687///post-translational protein modification+++GO:0097187///dentinogenesis+++GO:0046034///ATP metabolic process","TRIO and F-actin-binding protein-like","[FA20A_HUMAN|diamond]RecName: Full=Pseudokinase FAM20A {ECO:0000305}; Flags: Precursor;+++[FA20C_HUMAN|diamond]RecName: Full=Extracellular serine/threonine protein kinase FAM20C {ECO:0000305}; EC=2.7.11.1 {ECO:0000269|PubMed:22582013, ECO:0000269|PubMed:23754375, ECO:0000269|PubMed:25789606}; AltName: Full=Dentin matrix protein 4 {ECO:0000250|UniProtKB:Q5MJS3}; Short=DMP-4 {ECO:0000250|UniProtKB:Q5MJS3}; AltName: Full=Golgi casein kinase {ECO:0000303|PubMed:22582013}; AltName: Full=Golgi-enriched fraction casein kinase {ECO:0000303|PubMed:22582013}; Short=GEF-CK {ECO:0000303|PubMed:22582013}; Flags: Precursor;+++[FA20C_MOUSE|diamond]RecName: Full=Extracellular serine/threonine protein kinase FAM20C {ECO:0000305}; EC=2.7.11.1 {ECO:0000269|PubMed:22900076}; AltName: Full=Dentin matrix protein 4 {ECO:0000303|PubMed:17369251}; Short=DMP-4 {ECO:0000303|PubMed:17369251}; AltName: Full=Golgi-enriched fraction casein kinase {ECO:0000250|UniProtKB:Q8IXL6}; Short=GEF-CK {ECO:0000250|UniProtKB:Q8IXL6}; Flags: Precursor;"]
[105375131,"'LOC105375131'",0,2,0,0.666666666666667,{"$nulls":7},"basic proline-rich protein-like","[ELN_CHICK|diamond]RecName: Full=Elastin; AltName: Full=Tropoelastin; Flags: Precursor; Fragment;+++[QRIC2_HUMAN|diamond]RecName: Full=Glutamine-rich protein 2;+++[RRBP1_CANLF|diamond]RecName: Full=Ribosome-binding protein 1; AltName: Full=180 kDa ribosome receptor; Short=RRp;+++[RRBP1_HUMAN|diamond]RecName: Full=Ribosome-binding protein 1; AltName: Full=180 kDa ribosome receptor homolog; Short=RRp; AltName: Full=ES/130-related protein; AltName: Full=Ribosome receptor protein;"]
[105375355,"'UPK3B'",38823,34718,31914,35151.6666666667,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++04330///Notch signaling pathway","H01439///Williams-Beuren syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0010629///negative regulation of gene expression","uroplakin 3B","[UPK3B_HUMAN|Reviewed]RecName: Full=Uroplakin-3b; Short=UP3b; AltName: Full=Uroplakin IIIb; Short=UPIIIb; AltName: Full=p35; Flags: Precursor;+++[A0A0J9YVS6_HUMAN|Unreviewed]SubName: Full=Uroplakin-3b {ECO:0000313|Ensembl:ENSP00000487650};"]
[105375809,"'LOC105375809'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005576///extracellular region","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination","platelet endothelial aggregation receptor 1-like","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PO22_POPJA|diamond]RecName: Full=Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2; AltName: Full=Retrovirus-related Pol polyprotein from type I retrotransposable element R2; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; Flags: Fragment;+++[YTX2_XENLA|diamond]RecName: Full=Transposon TX1 uncharacterized 149 kDa protein; AltName: Full=ORF 2;"]
[105376204,"'LOC105376204'",13,7,9,9.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC105376204","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376353,"'LOC105376353'",53,71,39,54.3333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity",null,"mucin-5AC-like","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FTM_HUMAN|diamond]RecName: Full=Protein fantom; AltName: Full=Nephrocystin-8; AltName: Full=RPGR-interacting protein 1-like protein; Short=RPGRIP1-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105376525,"'LOC105376525'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003824///catalytic activity","GO:0008152///metabolic process","ectonucleotide pyrophosphatase/phosphodiesterase family member 7-like","[ENPP7_HUMAN|diamond]RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; Short=E-NPP 7; Short=NPP-7; EC=3.1.4.12 {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774, ECO:0000269|PubMed:15205117, ECO:0000269|PubMed:28292932}; AltName: Full=Alkaline sphingomyelin phosphodiesterase; AltName: Full=Intestinal alkaline sphingomyelinase {ECO:0000303|PubMed:12671034, ECO:0000303|PubMed:12885774}; Short=Alk-SMase {ECO:0000303|PubMed:12885774, ECO:0000303|PubMed:28292932}; Flags: Precursor;+++[ENPP7_RAT|diamond]RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; Short=E-NPP 7; Short=NPP-7; EC=3.1.4.12 {ECO:0000269|PubMed:15708357}; AltName: Full=Alkaline sphingomyelin phosphodiesterase; AltName: Full=Intestinal alkaline sphingomyelinase; Short=Alk-SMase; Flags: Precursor;"]
[105376526,"'LOC105376526'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0016021///integral component of membrane","GO:0003723///RNA binding","GO:0051028///mRNA transport","uncharacterized LOC105376526","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[ENR1_HUMAN|diamond]RecName: Full=Endogenous retrovirus group 3 member 1 Env polyprotein; AltName: Full=ERV-3 envelope protein; Short=ERV3 envelope protein; AltName: Full=ERV3-1 envelope protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-R envelope protein; Short=ERV-R envelope protein; AltName: Full=HERV-R_7q21.2 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ERK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Rec protein; AltName: Full=Endogenous retrovirus group K member 25; AltName: Full=HERV-K_11q22.1 provirus Rec protein;+++[POL1_MOUSE|diamond]RecName: Full=Retrovirus-related Pol polyprotein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; Flags: Fragment;+++[REC19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Rec protein; AltName: Full=HERV-K(C19) Rec protein; AltName: Full=HERV-K_19q11 provirus Rec protein;+++[REC6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Rec protein; AltName: Full=Central open reading frame; Short=c-orf; Short=cORF; AltName: Full=Endogenous retrovirus K protein 6; AltName: Full=HERV-K(C7) Rec protein; AltName: Full=HERV-K(HML-2.HOM) Rec protein; AltName: Full=HERV-K108 Rec protein; AltName: Full=HERV-K_7p22.1 provirus Rec protein; AltName: Full=K-Rev; AltName: Full=Rev-like protein; AltName: Full=Rev/Rex homolog;+++[REC9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Rec protein; AltName: Full=HERV-K(C6) Rec protein; AltName: Full=HERV-K109 Rec protein; AltName: Full=HERV-K_6q14.1 provirus Rec protein;+++[RECK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Rec protein; AltName: Full=HERV-K115 Rec protein; AltName: Full=HERV-K_8p23.1 provirus Rec protein;+++[SYCY2_CALJA|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PANTR|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PONPY|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ZMAT1_HUMAN|diamond]RecName: Full=Zinc finger matrin-type protein 1;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105376684,"'LOC105376684'",5.4,8.24,2.39,5.34333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"translation initiation factor IF-2-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376875,"'LOC105376875'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC105376875"]
[105376906,"'LOC105376906'",21.11,19.27,16.36,18.9133333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0015074///DNA integration","endogenous retrovirus group K member 19 Pol protein","[PO113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pol protein; AltName: Full=HERV-K113 Pol protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Pol protein; AltName: Full=HERV-K(C19) Pol protein; AltName: Full=HERV-K_19q11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;"]
[105376917,"'LOC105376917'",1.84,1,0,0.946666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0031093///platelet alpha granule lumen+++GO:0005576///extracellular region","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0008134///transcription factor binding","GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated+++GO:0002576///platelet degranulation+++GO:0048599///oocyte development","uncharacterized LOC105376917","[CE017_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C5orf17;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FIGLA_HUMAN|diamond]RecName: Full=Factor in the germline alpha; Short=FIGalpha; AltName: Full=Class C basic helix-loop-helix protein 8; Short=bHLHc8; AltName: Full=Folliculogenesis-specific basic helix-loop-helix protein; AltName: Full=Transcription factor FIGa;+++[FIGLA_MOUSE|diamond]RecName: Full=Factor in the germline alpha; Short=FIGalpha; AltName: Full=Transcription factor FIGa;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NR3L1_HUMAN|diamond]RecName: Full=Natural cytotoxicity triggering receptor 3 ligand 1; AltName: Full=B7 homolog 6; Short=B7-H6; Flags: Precursor;+++[NR3L1_PONAB|diamond]RecName: Full=Natural cytotoxicity triggering receptor 3 ligand 1; AltName: Full=B7 homolog 6; Short=B7-H6; Flags: Precursor;+++[TX264_HUMAN|diamond]RecName: Full=Testis-expressed protein 264; AltName: Full=Putative secreted protein Zsig11; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN431_HUMAN|diamond]RecName: Full=Zinc finger protein 431;+++[ZN492_HUMAN|diamond]RecName: Full=Zinc finger protein 492; AltName: Full=Zinc finger protein 115;+++[ZN730_HUMAN|diamond]RecName: Full=Putative zinc finger protein 730;+++[ZNF85_HUMAN|diamond]RecName: Full=Zinc finger protein 85; AltName: Full=Zinc finger protein HPF4; AltName: Full=Zinc finger protein HTF1;+++[ZNF98_HUMAN|diamond]RecName: Full=Zinc finger protein 98; AltName: Full=Zinc finger protein 739; AltName: Full=Zinc finger protein F7175;"]
[105377022,"'LOC105377022'",4,3,2,3,{"$nulls":7},"uncharacterized LOC105377022"]
[105377310,"'LOC105377310'",1,0,3,1.33333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane",null,"GO:0006949///syncytium formation","syncytin-1-like","[SYCY1_GORGO|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY1_HUMAN|diamond]RecName: Full=Syncytin-1; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Env-W; AltName: Full=Envelope polyprotein gPr73; AltName: Full=Enverin; AltName: Full=HERV-7q Envelope protein; AltName: Full=HERV-W envelope protein; AltName: Full=HERV-W_7q21.2 provirus ancestral Env polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; AltName: Full=gp50; Contains: RecName: Full=Transmembrane protein; Short=TM; AltName: Full=gp24; Flags: Precursor;+++[SYCY1_HYLPI|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY1_PANTR|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY1_PONPY|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[105377622,"'LOC105377622'",9,21,13,14.3333333333333,{"$nulls":7},"uncharacterized LOC105377622","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105377650,"'LOC105377650'",3,7,6,5.33333333333333,{"$nulls":7},"uncharacterized LOC105377650","[A0A1B0GRK0_MOUSE|diamond]SubName: Full=Predicted gene 45521 {ECO:0000313|Ensembl:ENSMUSP00000147554};+++[A0A2I2UDG9_FELCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000030524};+++[G3HFM3_CRIGR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGV92989.1};+++[L5K8U9_PTEAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELK07797.1};+++[S9WRC2_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY81017.1};"]
[105377805,"'LOC105377805'",13,13,9,11.6666666666667,{"$nulls":7},"basic salivary proline-rich protein 4-like","[A0A026VVN5_OOCBI|diamond]SubName: Full=F-box only protein {ECO:0000313|EMBL:EZA47853.1};+++[A0A060YYP9_ONCMY|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDQ96866.1}; Flags: Fragment;+++[A0A093I0R1_STRCA|diamond]SubName: Full=Putative proline-rich protein 21 {ECO:0000313|EMBL:KFV87521.1}; Flags: Fragment;+++[A0A099ZME2_TINGU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGL82088.1}; Flags: Fragment;+++[A0A2T7NET3_POMCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PVD19655.1};"]
[105378592,"'105378592'",3.58,3.58,1,2.72]
[105378862,"'LOC105378862'",32,28,35,31.6666666666667,{"$nulls":7},"translation initiation factor IF-2-like","[F6VET6_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000009862};+++[F7DFZ3_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000012093};+++[F7DXK1_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000017383};"]
[105378947,"'LOC105378947'",1,3.01,0,1.33666666666667,{"$nulls":7},"proline-rich extensin-like protein EPR1","[E2BKF3_HARSA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFN83838.1};"]
[105378949,"'LOC105378949'",14,18,16,16,{"$nulls":7},"collagen alpha-2(VIII) chain"]
[105378950,"'LOC105378950'",4,0,1,1.66666666666667,{"$nulls":7},"mitogen-activated protein kinase 7-like"]
[105379045,"'105379045'",0,1,1,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":7},"[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379177,"'LOC105379177'",6.03,6.09,6,6.04,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"uncharacterized LOC105379177","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379198,"'LOC105379198'",9,4,4,5.66666666666667,{"$nulls":5},"GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination","uncharacterized LOC105379198","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[105379356,"'LOC105379356'",4,2.27,3.06,3.11,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity",null,"uncharacterized LOC105379356","[A0A087X0J2_HUMAN|diamond]SubName: Full=UBX domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000483433}; Flags: Fragment;+++[A0A2U3ZSI3_ODORO|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC105758093 {ECO:0000313|RefSeq:XP_012421949.1};+++[Q1KYL9_MOUSE|diamond]SubName: Full=Gag-pro-pol polyprotein {ECO:0000313|EMBL:ABD14436.1}; Flags: Precursor;+++[Q1KYM2_MOUSE|diamond]SubName: Full=Gag-pro-pol polyprotein {ECO:0000313|EMBL:ABD14433.1}; Flags: Precursor;+++[Q86UH8_HUMAN|diamond]SubName: Full=Pol protein {ECO:0000313|EMBL:AAP29639.1};"]
[105379443,"'LOC105379443'",26.29,67.5,61.19,51.66,"04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal+++00670///One carbon pool by folate",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0016805///dipeptidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005524///ATP binding+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0008236///serine-type peptidase activity+++GO:0043565///sequence-specific DNA binding+++GO:0050129///N-formylglutamate deformylase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0004329///formate-tetrahydrofolate ligase activity","GO:0015942///formate metabolic process+++GO:0042135///neurotransmitter catabolic process+++GO:0046655///folic acid metabolic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0035999///tetrahydrofolate interconversion+++GO:0006760///folic acid-containing compound metabolic process+++GO:0001843///neural tube closure+++GO:0006351///transcription, DNA-templated+++GO:0009257///10-formyltetrahydrofolate biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0006310///DNA recombination+++GO:0006508///proteolysis+++GO:0048703///embryonic viscerocranium morphogenesis","monofunctional C1-tetrahydrofolate synthase, mitochondrial-like","[BEND2_HUMAN|diamond]RecName: Full=BEN domain-containing protein 2;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOXD4_HUMAN|diamond]RecName: Full=Forkhead box protein D4; AltName: Full=Forkhead-related protein FKHL9; AltName: Full=Forkhead-related transcription factor 5; Short=FREAC-5; AltName: Full=Myeloid factor-alpha;+++[FX4L3_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 3; Short=FOXD4-like 3;+++[FX4L4_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 4 {ECO:0000305}; Short=FOXD4-like 4 {ECO:0000305}; AltName: Full=Forkhead box protein D4-like 2 {ECO:0000312|HGNC:HGNC:23762}; AltName: Full=Forkhead box protein D4B {ECO:0000305|PubMed:12234674}; AltName: Full=Myeloid factor-gamma {ECO:0000312|EMBL:AAL73342.1};+++[FX4L5_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 5; Short=FOXD4-like 5;+++[FX4L6_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 6; Short=FOXD4-like 6;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379547,"'LOC105379547'",0,8,7,5,{"$nulls":7},"paraneoplastic antigen Ma6E-like","[A0A2I2YCC5_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000032450};+++[A0A2I2YHS6_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000034480};+++[A0A2I2Z815_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000043246};+++[A0A2I3ST96_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000080167};+++[A0A2I3TT44_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000092156};"]
[105379554,"'LOC105379554'",30.39,24.19,13.33,22.6366666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0036126///sperm flagellum+++GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0030317///flagellated sperm motility","maFF-interacting protein","[MAFIP_HUMAN|diamond]RecName: Full=MaFF-interacting protein; AltName: Full=Tektin-4 like protein PP5644;+++[TEKT4_BOVIN|diamond]RecName: Full=Tektin-4;+++[TEKT4_HUMAN|diamond]RecName: Full=Tektin-4;+++[TEKT4_MOUSE|diamond]RecName: Full=Tektin-4; AltName: Full=Testicular microtubules-related protein 4;+++[TEKT4_RAT|diamond]RecName: Full=Tektin-4;"]
[105379561,"'LOC105379561'",2,8,2,4,{"$nulls":7},"uncharacterized LOC105379561","[A0A0D9SCH2_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000018561};+++[A0A1A9ADJ3_9APIC|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:SBT54262.1};"]
[105379575,"'105379575'",0,1,1,0.666666666666667,{"$nulls":8},"[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A2_ASCSU|diamond]RecName: Full=Collagen alpha-2(IV) chain; Flags: Precursor;+++[CO4A2_CAEEL|diamond]RecName: Full=Collagen alpha-2(IV) chain; AltName: Full=Lethal protein 2; Flags: Precursor;+++[LWA_ANTEL|diamond]RecName: Full=LWamide neuropeptides; Contains: RecName: Full=LWamide I; Contains: RecName: Full=Metamorphosin A; Short=MMA; AltName: Full=LWamide II; Contains: RecName: Full=LWamide III; Contains: RecName: Full=LWamide IV; Contains: RecName: Full=LWamide V; Contains: RecName: Full=LWamide VI; Contains: RecName: Full=LWamide VII; Contains: RecName: Full=LWamide VIII; Contains: RecName: Full=LWamide IX; Flags: Precursor;+++[MUC2_HUMAN|diamond]RecName: Full=Mucin-2; Short=MUC-2; AltName: Full=Intestinal mucin-2; Flags: Precursor;"]
[105379752,"'LOC105379752'",1,3,1,1.66666666666667,{"$nulls":7},"uncharacterized LOC105379752","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[10539,"'GLRX3'",574,483,529,528.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005938///cell cortex+++GO:0030018///Z disc","GO:0009055///electron transfer activity+++GO:0003723///RNA binding+++GO:0015038///glutathione disulfide oxidoreductase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0051536///iron-sulfur cluster binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding","GO:0002026///regulation of the force of heart contraction+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0006879///cellular iron ion homeostasis+++GO:0022900///electron transport chain","glutaredoxin 3","[GLRX3_HUMAN|Reviewed]RecName: Full=Glutaredoxin-3; AltName: Full=PKC-interacting cousin of thioredoxin {ECO:0000303|PubMed:10636891}; Short=PICOT {ECO:0000303|PubMed:10636891}; AltName: Full=PKC-theta-interacting protein; Short=PKCq-interacting protein; AltName: Full=Thioredoxin-like protein 2;+++[A0A140VJK1_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 75 {ECO:0000313|EMBL:AEE60988.1};"]
[1054,"'CEBPG'",153,140,134,142.333333333333,"05152///Tuberculosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity","GO:0042267///natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0001889///liver development+++GO:0016071///mRNA metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043353///enucleate erythrocyte differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0043388///positive regulation of DNA binding+++GO:0030183///B cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity","CCAAT enhancer binding protein gamma","[CEBPG_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein gamma; Short=C/EBP gamma;"]
[10540,"'DCTN2'",2386,2241,2191,2272.66666666667,"04962///Vasopressin-regulated water reabsorption+++05016///Huntington's disease",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0031982///vesicle+++GO:0005829///cytosol+++GO:0000776///kinetochore+++GO:0030426///growth cone+++GO:0005869///dynactin complex+++GO:0005813///centrosome+++GO:0030286///dynein complex+++GO:0016020///membrane","GO:0019901///protein kinase binding+++GO:0003774///motor activity+++GO:0030507///spectrin binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007017///microtubule-based process+++GO:0008283///cell proliferation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0071539///protein localization to centrosome+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007052///mitotic spindle organization+++GO:0032402///melanosome transport+++GO:0000086///G2/M transition of mitotic cell cycle","dynactin subunit 2","[DCTN2_HUMAN|Reviewed]RecName: Full=Dynactin subunit 2; AltName: Full=50 kDa dynein-associated polypeptide; AltName: Full=Dynactin complex 50 kDa subunit; Short=DCTN-50; AltName: Full=p50 dynamitin;+++[A8K8J9_HUMAN|Unreviewed]SubName: Full=Dynactin 2 (P50), isoform CRA_b {ECO:0000313|EMBL:EAW97028.1}; SubName: Full=cDNA FLJ31120 fis, clone IMR322000730, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG51555.1}; SubName: Full=cDNA FLJ77785 {ECO:0000313|EMBL:BAF85053.1};+++[B3KTX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38923 fis, clone NT2NE2011823, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG53236.1};+++[F8VRV7_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448606}; Flags: Fragment;+++[F8VW18_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449855}; Flags: Fragment;+++[F8VX93_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449710}; Flags: Fragment;+++[F8W0U6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447553};+++[F8W1I6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000446964};+++[H0YHL1_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447308}; Flags: Fragment;+++[H0YI98_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448937}; Flags: Fragment;+++[V9HW58_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 77 {ECO:0000313|EMBL:ACI46007.1};"]
[10541,"'ANP32B'",1081,1246,1098,1141.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0070063///RNA polymerase binding+++GO:0042393///histone binding+++GO:0005515///protein binding","GO:0046827///positive regulation of protein export from nucleus+++GO:0021591///ventricular system development+++GO:0001944///vasculature development+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0048839///inner ear development+++GO:0045596///negative regulation of cell differentiation+++GO:0006334///nucleosome assembly+++GO:0060021///roof of mouth development","acidic nuclear phosphoprotein 32 family member B","[AN32B_HUMAN|Reviewed]RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member B; AltName: Full=Acidic protein rich in leucines; AltName: Full=Putative HLA-DR-associated protein I-2; Short=PHAPI2; AltName: Full=Silver-stainable protein SSP29;"]
[10542,"'LAMTOR5'",459,351,437,415.666666666667,"05161///Hepatitis B+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0071986///Ragulator complex+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071230///cellular response to amino acid stimulus+++GO:0009615///response to virus+++GO:0043066///negative regulation of apoptotic process+++GO:0008361///regulation of cell size+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0061462///protein localization to lysosome+++GO:0007050///cell cycle arrest+++GO:0019079///viral genome replication","late endosomal/lysosomal adaptor, MAPK and MTOR activator 5","[LTOR5_HUMAN|Reviewed]RecName: Full=Ragulator complex protein LAMTOR5; AltName: Full=Hepatitis B virus X-interacting protein; Short=HBV X-interacting protein; Short=HBX-interacting protein; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5;+++[A0A0C4DGV4_HUMAN|Unreviewed]SubName: Full=Hepatitis B virus x interacting protein {ECO:0000313|EMBL:EAW56447.1}; SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000480529};+++[E9PLX3_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000435085};+++[R4GMU8_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000473357};"]
[10544,"'PROCR'",280,247,253,260,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0038023///signaling receptor activity+++GO:0005515///protein binding","GO:0050819///negative regulation of coagulation+++GO:0007599///hemostasis+++GO:0007596///blood coagulation","protein C receptor","[EPCR_HUMAN|Reviewed]RecName: Full=Endothelial protein C receptor; AltName: Full=Activated protein C receptor; Short=APC receptor; AltName: Full=Endothelial cell protein C receptor; AltName: CD_antigen=CD201; Flags: Precursor;+++[A0A0U1RQQ4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489117}; Flags: Fragment;+++[A0A0U1RRC4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489456}; Flags: Fragment;"]
[10548,"'TM9SF1'",1616,1456,1403,1491.66666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0000421///autophagosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005764///lysosome+++GO:0016021///integral component of membrane",null,"GO:0072657///protein localization to membrane+++GO:0006914///autophagy","transmembrane 9 superfamily member 1","[TM9S1_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 1; AltName: Full=MP70 protein family member; Short=hMP70; Flags: Precursor;+++[B4E3A9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PJC4_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PJM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PL78_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PMQ9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PNW2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PP24_HUMAN|Unreviewed]SubName: Full=Transmembrane 9 superfamily member 1 {ECO:0000313|Ensembl:ENSP00000436486}; Flags: Fragment;+++[E9PQY7_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PS99_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[G3V1B9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[10549,"'PRDX4'",1544,1299,1320,1387.66666666667,"04214///Apoptosis - fly",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0005623///cell+++GO:0005790///smooth endoplasmic reticulum+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0004601///peroxidase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0051920///peroxiredoxin activity+++GO:0016209///antioxidant activity+++GO:0008379///thioredoxin peroxidase activity","GO:0007252///I-kappaB phosphorylation+++GO:0045454///cell redox homeostasis+++GO:0072593///reactive oxygen species metabolic process+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification+++GO:0019471///4-hydroxyproline metabolic process+++GO:0006979///response to oxidative stress+++GO:2000255///negative regulation of male germ cell proliferation+++GO:0022417///protein maturation by protein folding+++GO:0008584///male gonad development+++GO:0043312///neutrophil degranulation+++GO:0007283///spermatogenesis+++GO:0055114///oxidation-reduction process+++GO:0030198///extracellular matrix organization","peroxiredoxin 4","[PRDX4_HUMAN|Reviewed]RecName: Full=Peroxiredoxin-4; EC=1.11.1.15 {ECO:0000269|PubMed:21916849, ECO:0000269|PubMed:9388242}; AltName: Full=Antioxidant enzyme AOE372; Short=AOE37-2; AltName: Full=Peroxiredoxin IV; Short=Prx-IV; AltName: Full=Thioredoxin peroxidase AO372; AltName: Full=Thioredoxin-dependent peroxide reductase A0372; Flags: Precursor;+++[A6NG45_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368635};+++[A6NJJ0_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368654}; Flags: Fragment;+++[H7C3T4_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000413736}; Flags: Fragment;+++[V9HW63_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 97n {ECO:0000313|EMBL:ACI45989.1}; SubName: Full=Peroxiredoxin 4 {ECO:0000313|EMBL:EAW98996.1};"]
[10550,"'ARL6IP5'",2183,1654,1809,1882,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0002037///negative regulation of L-glutamate import across plasma membrane+++GO:0015813///L-glutamate transmembrane transport+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential","ADP ribosylation factor like GTPase 6 interacting protein 5","[PRAF3_HUMAN|Reviewed]RecName: Full=PRA1 family protein 3; AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 5; Short=ARL-6-interacting protein 5; Short=Aip-5; AltName: Full=Cytoskeleton-related vitamin A-responsive protein; AltName: Full=Dermal papilla-derived protein 11; AltName: Full=GTRAP3-18; AltName: Full=Glutamate transporter EAAC1-interacting protein; AltName: Full=JM5; AltName: Full=Prenylated Rab acceptor protein 2; AltName: Full=Protein JWa; AltName: Full=Putative MAPK-activating protein PM27;+++[A0A024R371_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[C9JQU6_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF33_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF90_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10551,"'AGR2'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0042803///protein homodimerization activity+++GO:0002162///dystroglycan binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding","GO:0010628///positive regulation of gene expression+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:1903899///positive regulation of PERK-mediated unfolded protein response+++GO:0070254///mucus secretion+++GO:0034976///response to endoplasmic reticulum stress+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:0060480///lung goblet cell differentiation+++GO:0048639///positive regulation of developmental growth+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0060548///negative regulation of cell death+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0048546///digestive tract morphogenesis","anterior gradient 2, protein disulphide isomerase family member","[AGR2_HUMAN|Reviewed]RecName: Full=Anterior gradient protein 2 homolog; Short=AG-2; Short=hAG-2; AltName: Full=HPC8; AltName: Full=Secreted cement gland protein XAG-2 homolog; Flags: Precursor;+++[B5MC07_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000386025};+++[C9J3E2_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000411969}; Flags: Fragment;+++[H7C3Z9_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000414806}; Flags: Fragment;+++[Q4JM46_HUMAN|Unreviewed]SubName: Full=AGR2 {ECO:0000313|EMBL:AAY84774.1}; SubName: Full=Anterior gradient 2 homolog (Xenopus laevis) {ECO:0000313|EMBL:EAL24283.1}; SubName: Full=Anterior gradient 2 homolog (Xenopus laevis), isoform CRA_a {ECO:0000313|EMBL:EAW93682.1}; SubName: Full=Anterior gradient 2 splice variant C {ECO:0000313|EMBL:AJO53280.1}; SubName: Full=Epididymis secretory protein Li 116 {ECO:0000313|EMBL:ACI45999.1};+++[Q4JM47_HUMAN|Unreviewed]SubName: Full=AGR2 {ECO:0000313|EMBL:AAY84773.1};"]
[10552,"'ARPC1A'",1378,1553,1394,1441.66666666667,"05130///Pathogenic Escherichia coli infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++05131///Shigellosis",{"$nulls":3},"GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030833///regulation of actin filament polymerization+++GO:0061024///membrane organization","actin related protein 2/3 complex subunit 1A","[ARC1A_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1A; AltName: Full=SOP2-like protein;+++[A0A0K0K1L3_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 307 {ECO:0000313|EMBL:ACV87209.1}; Flags: Fragment;+++[E9PF58_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1A {ECO:0000313|Ensembl:ENSP00000408711};+++[Q75MY0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ARPC1A {ECO:0000313|EMBL:AAS00381.1}; Flags: Fragment;+++[V9HVZ6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};"]
[10553,"'HTATIP2'",137,100,126,121,{"$nulls":4},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0045765///regulation of angiogenesis+++GO:0051170///import into nucleus+++GO:0030154///cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0016032///viral process+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development","HIV-1 Tat interactive protein 2","[HTAI2_HUMAN|Reviewed]RecName: Full=Oxidoreductase HTATIP2; EC=1.1.1.-; AltName: Full=30 kDa HIV-1 TAT-interacting protein; AltName: Full=HIV-1 TAT-interactive protein 2;+++[E9PI87_HUMAN|Unreviewed]SubName: Full=Oxidoreductase HTATIP2 {ECO:0000313|Ensembl:ENSP00000436729};"]
[10554,"'AGPAT1'",3879,3669,3609,3719,"00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate+++R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0006629///lipid metabolic process+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0001819///positive regulation of cytokine production+++GO:0031325///positive regulation of cellular metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process","1-acylglycerol-3-phosphate O-acyltransferase 1","[PLCA_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 1; Short=1-AGP acyltransferase 1; Short=1-AGPAT 1; AltName: Full=Lysophosphatidic acid acyltransferase alpha; Short=LPAAT-alpha; AltName: Full=Protein G15; Flags: Precursor;+++[A0A024RCV5_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};"]
[10555,"'AGPAT2'",900,881,833,871.333333333333,"00564///Glycerophospholipid metabolism+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA+++R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0035579///specific granule membrane","GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity","GO:0042493///response to drug+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008544///epidermis development+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0001819///positive regulation of cytokine production+++GO:0043312///neutrophil degranulation+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","1-acylglycerol-3-phosphate O-acyltransferase 2","[PLCB_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase beta; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2; Short=1-AGP acyltransferase 2; Short=1-AGPAT 2; AltName: Full=Lysophosphatidic acid acyltransferase beta; Short=LPAAT-beta; Flags: Precursor;+++[A0A024R8F9_HUMAN|Unreviewed]SubName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2 (Lysophosphatidic acid acyltransferase, beta), isoform CRA_b {ECO:0000313|EMBL:EAW88252.1}; SubName: Full=Testicular tissue protein Li 143 {ECO:0000313|EMBL:AEE61054.1};+++[A0A024R8I7_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q8WUW2_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q96IS9_HUMAN|Unreviewed]SubName: Full=AGPAT2 protein {ECO:0000313|EMBL:AAH07269.1}; Flags: Fragment;"]
[10556,"'RPP30'",155,130,142,142.333333333333,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex+++GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004540///ribonuclease activity+++GO:0004526///ribonuclease P activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity","GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","ribonuclease P/MRP subunit p30","[RPP30_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p30; Short=RNaseP protein p30; EC=3.1.26.5; AltName: Full=RNase P subunit 2;+++[Q5VU10_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000407972}; Flags: Fragment;+++[Q5VU11_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000277882}; Flags: Fragment;"]
[10557,"'RPP38'",253,240,253,248.666666666667,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090501///RNA phosphodiester bond hydrolysis","ribonuclease P/MRP subunit p38","[RPP38_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p38; Short=RNaseP protein p38; EC=3.1.26.5;+++[Q5VUC3_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000402635}; Flags: Fragment;+++[Q5VUC9_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000367443};"]
[10558,"'SPTLC1'",682,610,579,623.666666666667,"00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway+++01100///Metabolic pathways+++04138///Autophagy - yeast","H00265///Hereditary sensory and autonomic neuropathy (HSAN)","M00099///Sphingosine biosynthesis+++M00094///Ceramide biosynthesis","R01281///Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)   Palmitoyl-CoA + L-Serine <=> 3-Dehydrosphinganine + CoA + CO2","GO:0017059///serine C-palmitoyltransferase complex+++GO:0016020///membrane+++GO:0035339///SPOTS complex+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0030170///pyridoxal phosphate binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0004758///serine C-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0030148///sphingolipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0046511///sphinganine biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0046513///ceramide biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046512///sphingosine biosynthetic process+++GO:1904504///positive regulation of lipophagy","serine palmitoyltransferase long chain base subunit 1","[SPTC1_HUMAN|Reviewed]RecName: Full=Serine palmitoyltransferase 1; EC=2.3.1.50; AltName: Full=Long chain base biosynthesis protein 1; Short=LCB 1; AltName: Full=Serine-palmitoyl-CoA transferase 1; Short=SPT 1; Short=SPT1;+++[A0A024R277_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase, long chain base subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW62805.1};+++[A0A2R8Y4S0_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000493933};+++[A0A2R8Y6A2_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495388};+++[A0A2R8Y763_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495764}; Flags: Fragment;+++[L8E7V1_HUMAN|Unreviewed]SubName: Full=Alternative protein SPTLC1 {ECO:0000313|EMBL:CCQ43355.1};+++[Q6NUL7_HUMAN|Unreviewed]SubName: Full=SPTLC1 protein {ECO:0000313|EMBL:AAH68537.1};"]
[10559,"'SLC35A1'",120,92,75,95.6666666666667,"04137///Mitophagy - animal+++00970///Aminoacyl-tRNA biosynthesis+++04140///Autophagy - animal","H01392///Arthrogryposis, mental retardation, and seizures (AMRS)+++H00606///Early infantile epileptic encephalopathy+++H00119///Congenital disorders of glycosylation (CDG) type II","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03646///L-Arginine:tRNA(Arg) ligase (AMP-forming) ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)","GO:0005794///Golgi apparatus+++GO:0030173///integral component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0015136///sialic acid transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity+++GO:0005456///CMP-N-acetylneuraminate transmembrane transporter activity","GO:0015782///CMP-N-acetylneuraminate transmembrane transport+++GO:0008643///carbohydrate transport+++GO:0015739///sialic acid transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport+++GO:0006464///cellular protein modification process+++GO:0005975///carbohydrate metabolic process","solute carrier family 35 member A1","[S35A1_HUMAN|Reviewed]RecName: Full=CMP-sialic acid transporter; Short=CMP-SA-Tr; Short=CMP-Sia-Tr; AltName: Full=Solute carrier family 35 member A1;+++[A0A087WVM1_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|Ensembl:ENSP00000479535};+++[Q5W1L6_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65470.1};+++[Q5W1L7_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65469.1, ECO:0000313|Ensembl:ENSP00000358570};+++[Q6A0F2_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17781.1};+++[Q6A0F3_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17780.1};"]
[1056,"'CEL'",74,113,82,89.6666666666667,"04975///Fat digestion and absorption+++01100///Metabolic pathways+++00561///Glycerolipid metabolism+++00100///Steroid biosynthesis+++04972///Pancreatic secretion","H00410///Maturity onset diabetes of the young (MODY)","M00098///Acylglycerol degradation","R01462///cholesterol ester acylhydrolase   Cholesterol ester + H2O <=> Cholesterol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase   1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid+++R02250///triacylglycerol acylhydrolase   Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid","GO:0009986///cell surface+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0098793///presynapse+++GO:0005737///cytoplasm","GO:0004806///triglyceride lipase activity+++GO:0042043///neurexin family protein binding+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003824///catalytic activity+++GO:0038023///signaling receptor activity+++GO:0004771///sterol esterase activity+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016787///hydrolase activity","GO:0006629///lipid metabolic process+++GO:0044258///intestinal lipid catabolic process+++GO:0007158///neuron cell-cell adhesion+++GO:0016042///lipid catabolic process+++GO:0044241///lipid digestion+++GO:0006707///cholesterol catabolic process+++GO:0097104///postsynaptic membrane assembly+++GO:0050804///modulation of chemical synaptic transmission+++GO:0018350///protein esterification+++GO:0030299///intestinal cholesterol absorption+++GO:0097105///presynaptic membrane assembly+++GO:0009062///fatty acid catabolic process+++GO:0046514///ceramide catabolic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0030157///pancreatic juice secretion","carboxyl ester lipase","[CEL_HUMAN|Reviewed]RecName: Full=Bile salt-activated lipase; Short=BAL; EC=3.1.1.13; EC=3.1.1.3; AltName: Full=Bile salt-stimulated lipase; Short=BSSL; AltName: Full=Bucelipase; AltName: Full=Carboxyl ester lipase; AltName: Full=Cholesterol esterase; AltName: Full=Pancreatic lysophospholipase; AltName: Full=Sterol esterase; Flags: Precursor;+++[B4DSX9_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};+++[O75612_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[Q86SR3_HUMAN|Unreviewed]SubName: Full=CEL protein {ECO:0000313|EMBL:AAH42510.1};+++[X6R868_HUMAN|Unreviewed]SubName: Full=Bile salt-activated lipase {ECO:0000313|Ensembl:ENSP00000361151};"]
[10560,"'SLC19A2'",242,206,211,219.666666666667,"04977///Vitamin digestion and absorption","H01231///Biotin-responsive basal ganglia disease (BBGD)+++H01183///Thiamine-responsive megaloblastic anemia (TRMA)+++H01565///Wernicke encephalopathy",null,null,"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0015234///thiamine transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity","GO:0042723///thiamine-containing compound metabolic process+++GO:0071934///thiamine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0015888///thiamine transport+++GO:0035461///vitamin transmembrane transport+++GO:0015884///folic acid transport+++GO:0051180///vitamin transport","solute carrier family 19 member 2","[S19A2_HUMAN|Reviewed]RecName: Full=Thiamine transporter 1; Short=ThTr-1; Short=ThTr1; AltName: Full=Solute carrier family 19 member 2; AltName: Full=Thiamine carrier 1; Short=TC1;+++[A0A024R8Y5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_c {ECO:0000313|EMBL:EAW90847.1}; SubName: Full=Solute carrier family 19 member 2 isoform 1 {ECO:0000313|EMBL:ALQ33992.1};+++[A0A024R928_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_a {ECO:0000313|EMBL:EAW90845.1}; SubName: Full=Solute carrier family 19 member 2 isoform 2 {ECO:0000313|EMBL:ALQ33993.1};+++[A0A2R8Y5B5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_b {ECO:0000313|EMBL:EAW90844.1}; SubName: Full=Thiamine transporter 1 {ECO:0000313|Ensembl:ENSP00000494404};+++[B0FBR7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 thiamine transporter member 2 {ECO:0000313|EMBL:ABY51619.1}; Flags: Fragment;+++[E3UTN9_HUMAN|Unreviewed]SubName: Full=SLC19A2 solute carrier family 19 member 2 {ECO:0000313|EMBL:ADP24156.1}; Flags: Fragment;+++[I7BB09_HUMAN|Unreviewed]SubName: Full=Thiamnine trasporter protein {ECO:0000313|EMBL:AFO38177.2}; Flags: Fragment;+++[Q7Z7J1_HUMAN|Unreviewed]SubName: Full=Thiamine transporter THTR-1 {ECO:0000313|EMBL:AAP37965.1}; Flags: Fragment;"]
[10561,"'IFI44'",13,7,5,8.33333333333333,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005525///GTP binding","GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0009615///response to virus","interferon induced protein 44","[IFI44_HUMAN|Reviewed]RecName: Full=Interferon-induced protein 44; Short=p44; AltName: Full=Microtubule-associated protein 44;+++[C9JUM8_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000399477}; Flags: Fragment;+++[H7C1F3_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000400001}; Flags: Fragment;"]
[10562,"'OLFM4'",2,2,1,1.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0042582///azurophil granule+++GO:1904724///tertiary granule lumen+++GO:0030141///secretory granule+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion+++GO:0005576///extracellular region+++GO:0042581///specific granule+++GO:0035580///specific granule lumen","GO:0003824///catalytic activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0010939///regulation of necrotic cell death+++GO:0042981///regulation of apoptotic process+++GO:0051260///protein homooligomerization+++GO:0007155///cell adhesion+++GO:0050764///regulation of phagocytosis+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0043312///neutrophil degranulation+++GO:2000389///regulation of neutrophil extravasation","olfactomedin 4","[OLFM4_HUMAN|Reviewed]RecName: Full=Olfactomedin-4; Short=OLM4; AltName: Full=Antiapoptotic protein GW112; AltName: Full=G-CSF-stimulated clone 1 protein; Short=hGC-1; AltName: Full=hOLfD; Flags: Precursor;+++[A0A024QZ95_HUMAN|Unreviewed]SubName: Full=Olfactomedin 4, isoform CRA_a {ECO:0000313|EMBL:EAW52053.1};"]
[10564,"'ARFGEF2'",662,747,729,712.666666666667,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0005829///cytosol+++GO:0005879///axonemal microtubule+++GO:0032279///asymmetric synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0043197///dendritic spine+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0030054///cell junction+++GO:0032280///symmetric synapse+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0005856///cytoskeleton+++GO:0055037///recycling endosome+++GO:0030425///dendrite+++GO:0005815///microtubule organizing center+++GO:0005768///endosome+++GO:0042995///cell projection","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0050811///GABA receptor binding","GO:0032012///regulation of ARF protein signal transduction+++GO:0006887///exocytosis+++GO:0001881///receptor recycling+++GO:0006893///Golgi to plasma membrane transport+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0007032///endosome organization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction","ADP ribosylation factor guanine nucleotide exchange factor 2","[BIG2_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Short=Brefeldin A-inhibited GEP 2; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2;+++[L8E9E5_HUMAN|Unreviewed]SubName: Full=Alternative protein ARFGEF2 {ECO:0000313|EMBL:CCQ43356.1};+++[Q59FR3_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2 variant {ECO:0000313|EMBL:BAD92634.1}; Flags: Fragment;+++[Q86TH5_HUMAN|Unreviewed]SubName: Full=ARFGEF2 protein {ECO:0000313|EMBL:AAH50449.1}; Flags: Fragment;"]
[10565,"'ARFGEF1'",1011,906,859,925.333333333333,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0000139///Golgi membrane+++GO:0016363///nuclear matrix+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005096///GTPase activator activity+++GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0051897///positive regulation of protein kinase B signaling+++GO:0090284///positive regulation of protein glycosylation in Golgi+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0034260///negative regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0090303///positive regulation of wound healing+++GO:0030837///negative regulation of actin filament polymerization+++GO:0006887///exocytosis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0031175///neuron projection development","ADP ribosylation factor guanine nucleotide exchange factor 1","[BIG1_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Short=Brefeldin A-inhibited GEP 1; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1; AltName: Full=p200 ARF guanine nucleotide exchange factor; AltName: Full=p200 ARF-GEP1;+++[A0A024R7X0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1(Brefeldin A-inhibited), isoform CRA_a {ECO:0000313|EMBL:EAW86936.1};+++[E5RHL7_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000430891}; Flags: Fragment;+++[E5RHZ1_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429560}; Flags: Fragment;+++[E5RIF2_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000428429}; Flags: Fragment;+++[E5RJN9_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429002}; Flags: Fragment;"]
[10566,"'AKAP3'",8,14,23,15,{"$nulls":4},"GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0097228///sperm principal piece","GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0007340///acrosome reaction+++GO:0008104///protein localization+++GO:0007338///single fertilization+++GO:0001835///blastocyst hatching+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway","A-kinase anchoring protein 3","[AKAP3_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 3; Short=AKAP-3; AltName: Full=A-kinase anchor protein 110 kDa; Short=AKAP 110; AltName: Full=Cancer/testis antigen 82; Short=CT82; AltName: Full=Fibrous sheath protein of 95 kDa; Short=FSP95; AltName: Full=Fibrousheathin I; AltName: Full=Fibrousheathin-1; AltName: Full=Protein kinase A-anchoring protein 3; Short=PRKA3; AltName: Full=Sperm oocyte-binding protein;+++[F5H2S4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000439382}; Flags: Fragment;+++[F5H7P4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000442376}; Flags: Fragment;+++[V9HWD4_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 159 {ECO:0000313|EMBL:ACJ13735.1};"]
[10567,"'RABAC1'",1492,1177,1243,1304,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0005794///Golgi apparatus+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0070064///proline-rich region binding",null,"Rab acceptor 1","[PRAF1_HUMAN|Reviewed]RecName: Full=Prenylated Rab acceptor protein 1; AltName: Full=PRA1 family protein 1;+++[M0QXH1_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0QXU8_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[M0R1H9_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0R3D4_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10568,"'SLC34A2'",8,6,2,5.33333333333333,"04928///Parathyroid hormone synthesis, secretion and action","H00888///Nephrolithiasis/osteoporosis, hypophosphatemic+++H02138///Hereditary hypophophatemic rickets with hypercalciuria+++H01198///Fanconi renotubular syndrome (FTS)+++H00214///Hypophosphatemic rickets+++H01298///Pulmonary alveolar microlithiasis (PALM)",null,null,"GO:0031982///vesicle+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0016020///membrane+++GO:0005903///brush border","GO:0042301///phosphate ion binding+++GO:0015321///sodium-dependent phosphate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0005436///sodium:phosphate symporter activity+++GO:0031402///sodium ion binding","GO:0006817///phosphate ion transport+++GO:0001701///in utero embryonic development+++GO:0055085///transmembrane transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0006811///ion transport+++GO:0044267///cellular protein metabolic process+++GO:0043627///response to estrogen+++GO:0044341///sodium-dependent phosphate transport+++GO:0035725///sodium ion transmembrane transport+++GO:0006814///sodium ion transport","solute carrier family 34 member 2","[NPT2B_HUMAN|Reviewed]RecName: Full=Sodium-dependent phosphate transport protein 2B; Short=Sodium-phosphate transport protein 2B; AltName: Full=Na(+)-dependent phosphate cotransporter 2B; AltName: Full=NaPi3b; AltName: Full=Sodium/phosphate cotransporter 2B; Short=Na(+)/Pi cotransporter 2B; Short=NaPi-2b; AltName: Full=Solute carrier family 34 member 2;+++[A0A0B5E3E9_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|EMBL:AJE59606.1}; Flags: Fragment;+++[D6RA94_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|Ensembl:ENSP00000423038}; Flags: Fragment;+++[D6RBC0_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|Ensembl:ENSP00000424266}; Flags: Fragment;"]
[10569,"'SLU7'",602,545,562.88,569.96,"03040///Spliceosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0030628///pre-mRNA 3'-splice site binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0000386///second spliceosomal transesterification activity","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006406///mRNA export from nucleus+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000389///mRNA 3'-splice site recognition+++GO:0034605///cellular response to heat+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0006886///intracellular protein transport","SLU7 homolog, splicing factor","[SLU7_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SLU7; Short=hSlu7;+++[A0A0C4DGD2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428362}; Flags: Fragment;+++[E5RGM7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000429990}; Flags: Fragment;+++[E5RK41_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428943}; Flags: Fragment;"]
[10570,"'DPYSL4'",963,975,834,924,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0031005///filamin binding","GO:0097485///neuron projection guidance+++GO:0070997///neuron death+++GO:0007399///nervous system development","dihydropyrimidinase like 4","[DPYL4_HUMAN|Reviewed]RecName: Full=Dihydropyrimidinase-related protein 4; Short=DRP-4; AltName: Full=Collapsin response mediator protein 3; Short=CRMP-3; AltName: Full=UNC33-like phosphoprotein 4; Short=ULIP-4;+++[D3DRG7_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-like 4, isoform CRA_a {ECO:0000313|EMBL:EAW49133.1};+++[Q5T0Q6_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-related protein 4 {ECO:0000313|Ensembl:ENSP00000357616};"]
[10572,"'SIVA1'",229,235,236,233.333333333333,"04115///p53 signaling pathway",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0001618///virus receptor activity+++GO:0046872///metal ion binding+++GO:0005175///CD27 receptor binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0008270///zinc ion binding","GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006915///apoptotic process+++GO:0046718///viral entry into host cell+++GO:0006924///activation-induced cell death of T cells+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0016032///viral process+++GO:0097191///extrinsic apoptotic signaling pathway","SIVA1 apoptosis inducing factor","[SIVA_HUMAN|Reviewed]RecName: Full=Apoptosis regulatory protein Siva; AltName: Full=CD27-binding protein; Short=CD27BP;+++[B4DTY2_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79449, highly similar to Apoptosis regulatory protein Siva {ECO:0000313|EMBL:BAG65628.1};+++[G3V3U1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451427};+++[G3V439_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451570}; Flags: Fragment;+++[H0YJN1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451823};"]
[10573,"'MRPL28'",1022,1199,1132,1117.66666666667,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005761///mitochondrial ribosome+++GO:0005739///mitochondrion","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","mitochondrial ribosomal protein L28","[RM28_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L28, mitochondrial; Short=L28mt; Short=MRP-L28; AltName: Full=Melanoma antigen p15; AltName: Full=Melanoma-associated antigen recognized by T-lymphocytes; AltName: Full=Mitochondrial large ribosomal subunit protein bL28m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[P13986_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:CAA34647.1};+++[Q9NRK2_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAF76751.1};+++[Q9UM95_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAD14186.1}; Flags: Fragment;"]
[10574,"'CCT7'",2641,2689,2542,2624,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0005874///microtubule+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0050821///protein stabilization+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0006457///protein folding","chaperonin containing TCP1 subunit 7","[TCPH_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit eta; Short=TCP-1-eta; AltName: Full=CCT-eta; AltName: Full=HIV-1 Nef-interacting protein; Contains: RecName: Full=T-complex protein 1 subunit eta, N-terminally processed;+++[A0A0D9SG95_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[B7Z1C9_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[F8WAM2_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042}; Flags: Fragment;+++[F8WBP8_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[Q6IBT3_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};"]
[10575,"'CCT4'",2014,1790,1831,1878.33333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005832///chaperonin-containing T-complex+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0002199///zona pellucida receptor complex+++GO:0042470///melanosome+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0005874///microtubule","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0051082///unfolded protein binding","GO:1904871///positive regulation of protein localization to Cajal body+++GO:0090666///scaRNA localization to Cajal body+++GO:0006457///protein folding+++GO:0050821///protein stabilization+++GO:0051973///positive regulation of telomerase activity+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida","chaperonin containing TCP1 subunit 4","[TCPD_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit delta; Short=TCP-1-delta; AltName: Full=CCT-delta; AltName: Full=Stimulator of TAR RNA-binding;"]
[10576,"'CCT2'",1432,1288,1245,1321.66666666667,{"$nulls":4},"GO:0044297///cell body+++GO:0043209///myelin sheath+++GO:0005874///microtubule+++GO:0002199///zona pellucida receptor complex+++GO:0005829///cytosol+++GO:0035578///azurophil granule lumen+++GO:0005832///chaperonin-containing T-complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005524///ATP binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0050821///protein stabilization+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:0051086///chaperone mediated protein folding independent of cofactor+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0090666///scaRNA localization to Cajal body+++GO:0007339///binding of sperm to zona pellucida+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0043312///neutrophil degranulation+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0006457///protein folding","chaperonin containing TCP1 subunit 2","[TCPB_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;+++[F5GWF6_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000441847};+++[F8VQ14_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000450153};+++[V9HW96_HUMAN|Unreviewed]SubName: Full=Chaperonin containing TCP1, subunit 2 (Beta), isoform CRA_b {ECO:0000313|EMBL:EAW97229.1}; SubName: Full=Epididymis secretory sperm binding protein Li 100n {ECO:0000313|EMBL:ACI46043.1};"]
[10577,"'NPC2'",9792,8359,8509,8886.66666666667,"04142///Lysosome+++04979///Cholesterol metabolism","H00136///Niemann-Pick disease type C (NPC)",null,null,"GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035578///azurophil granule lumen+++GO:0043202///lysosomal lumen+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005623///cell","GO:0019899///enzyme binding+++GO:0017127///cholesterol transporter activity+++GO:0015485///cholesterol binding+++GO:0005515///protein binding","GO:0030301///cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0046836///glycolipid transport+++GO:0015914///phospholipid transport+++GO:0032366///intracellular sterol transport+++GO:0008202///steroid metabolic process+++GO:0043312///neutrophil degranulation+++GO:0042632///cholesterol homeostasis+++GO:0006869///lipid transport+++GO:0034383///low-density lipoprotein particle clearance+++GO:0019747///regulation of isoprenoid metabolic process+++GO:0006629///lipid metabolic process+++GO:0009615///response to virus+++GO:0032367///intracellular cholesterol transport+++GO:0008203///cholesterol metabolic process","NPC intracellular cholesterol transporter 2","[NPC2_HUMAN|Reviewed]RecName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000312|HGNC:HGNC:14537}; AltName: Full=Epididymal secretory protein E1; AltName: Full=Human epididymis-specific protein 1; Short=He1 {ECO:0000303|PubMed:11125141, ECO:0000303|PubMed:8418812}; AltName: Full=Niemann-Pick disease type C2 protein {ECO:0000303|PubMed:17018531}; Flags: Precursor;+++[A0A024R6C0_HUMAN|Unreviewed]SubName: Full=Niemann-Pick disease, type C2, isoform CRA_a {ECO:0000313|EMBL:EAW81177.1};+++[E7EMS2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000412103};+++[G3V2V8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450887}; Flags: Fragment;+++[G3V3D1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451180}; Flags: Fragment;+++[G3V3E8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451206};+++[H0YIZ1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450502}; Flags: Fragment;+++[H0YJE2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451314}; Flags: Fragment;+++[J3KMY5_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000238633};"]
[10579,"'TACC2'",495,554,487,512,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0035257///nuclear hormone receptor binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization","transforming acidic coiled-coil containing protein 2","[TACC2_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 2; AltName: Full=Anti-Zuai-1; Short=AZU-1;+++[A0A0U1RRM9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489610}; Flags: Fragment;+++[B2RWP4_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI50628.1};+++[B7ZMJ9_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI44600.1};+++[D6RAA5_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422815};+++[E7EMZ9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000427618};+++[E9PBC6_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424467};+++[E9PGB3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000420967}; Flags: Fragment;+++[H0Y8P9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000421702}; Flags: Fragment;+++[H0Y911_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422725}; Flags: Fragment;+++[H0Y954_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423069}; Flags: Fragment;+++[H0Y9C3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423764}; Flags: Fragment;+++[H0Y9Y7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425525}; Flags: Fragment;+++[H0YA73_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000426303}; Flags: Fragment;+++[Q4VXL4_HUMAN|Unreviewed]SubName: Full=HCG41426, isoform CRA_c {ECO:0000313|EMBL:EAW49324.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357997};+++[Q4VXL8_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357995};"]
[1058,"'CENPA'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000786///nucleosome+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0000775///chromosome, centromeric region+++GO:0000939///condensed chromosome inner kinetochore+++GO:0000788///nuclear nucleosome+++GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0031618///nuclear pericentric heterochromatin","GO:0003682///chromatin binding+++GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0016032///viral process+++GO:0000132///establishment of mitotic spindle orientation+++GO:0006334///nucleosome assembly+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0051382///kinetochore assembly+++GO:0000281///mitotic cytokinesis","centromere protein A","[CENPA_HUMAN|Reviewed]RecName: Full=Histone H3-like centromeric protein A; AltName: Full=Centromere autoantigen A; AltName: Full=Centromere protein A; Short=CENP-A;+++[F8WD88_HUMAN|Unreviewed]SubName: Full=Histone H3-like centromeric protein A {ECO:0000313|Ensembl:ENSP00000404963};"]
[10580,"'SORBS1'",228,252,224,234.666666666667,"03320///PPAR signaling pathway+++04910///Insulin signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005899///insulin receptor complex+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0045121///membrane raft+++GO:0005924///cell-substrate adherens junction+++GO:0005813///centrosome+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0005915///zonula adherens+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix+++GO:0005913///cell-cell adherens junction","GO:0005515///protein binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005158///insulin receptor binding+++GO:0008092///cytoskeletal protein binding+++GO:0003779///actin binding","GO:0048041///focal adhesion assembly+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046326///positive regulation of glucose import+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0043149///stress fiber assembly+++GO:0032869///cellular response to insulin stimulus+++GO:0006936///muscle contraction+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007160///cell-matrix adhesion+++GO:0007015///actin filament organization","sorbin and SH3 domain containing 1","[SRBS1_HUMAN|Reviewed]RecName: Full=Sorbin and SH3 domain-containing protein 1; AltName: Full=Ponsin; AltName: Full=SH3 domain protein 5; AltName: Full=SH3P12; AltName: Full=c-Cbl-associated protein; Short=CAP;+++[A0A0U1RQI5_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000489022}; Flags: Fragment;+++[B4DTX5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60072, highly similar to Homo sapiens sorbin and SH3 domain containing 1 (SORBS1), transcript variant 6, mRNA {ECO:0000313|EMBL:BAG62137.1};+++[D3DR43_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain containing 1, isoform CRA_e {ECO:0000313|EMBL:EAW50004.1};+++[Q5T925_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000360272}; Flags: Fragment;+++[S4R303_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000473813}; Flags: Fragment;+++[S4R406_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000474932}; Flags: Fragment;"]
[10581,"'IFITM2'",771,725,753,749.666666666667,"04662///B cell receptor signaling pathway","H00506///Osteogenesis imperfecta",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0005886///plasma membrane",null,"GO:0035456///response to interferon-beta+++GO:0035455///response to interferon-alpha+++GO:0051607///defense response to virus+++GO:0009615///response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0006955///immune response+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0034341///response to interferon-gamma+++GO:0046597///negative regulation of viral entry into host cell+++GO:0002376///immune system process","interferon induced transmembrane protein 2","[IFM2_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 2; AltName: Full=Dispanin subfamily A member 2c; Short=DSPA2c; AltName: Full=Interferon-inducible protein 1-8D;+++[E9PQN9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000434443};+++[H0YCL2_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000431850}; Flags: Fragment;+++[H7BYV1_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000382712}; Flags: Fragment;+++[Q6IBB0_HUMAN|Unreviewed]SubName: Full=IFITM2 protein {ECO:0000313|EMBL:CAG33175.1}; SubName: Full=Interferon induced transmembrane protein 2 (1-8D) {ECO:0000313|EMBL:AAP88861.1};"]
[10584,"'COLEC10'",1,0,1,0.666666666666667,"04380///Osteoclast differentiation+++04060///Cytokine-cytokine receptor interaction","H01887///3MC syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0048029///monosaccharide binding+++GO:0004252///serine-type endopeptidase activity+++GO:0005537///mannose binding+++GO:0042056///chemoattractant activity+++GO:0030246///carbohydrate binding","GO:0006956///complement activation+++GO:0050918///positive chemotaxis+++GO:1904888///cranial skeletal system development+++GO:0001867///complement activation, lectin pathway+++GO:0006508///proteolysis","collectin subfamily member 10","[COL10_HUMAN|Reviewed]RecName: Full=Collectin-10; AltName: Full=Collectin liver protein 1; Short=CL-L1; AltName: Full=Collectin-34; Short=CL-34; Flags: Precursor;+++[A0A024R9J3_HUMAN|Unreviewed]SubName: Full=Collectin sub-family member 10 (C-type lectin), isoform CRA_a {ECO:0000313|EMBL:EAW91980.1};"]
[10585,"'POMT1'",953,936,920.1,936.366666666667,"00515///Mannose type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++01100///Metabolic pathways","H01960///Muscular dystrophy-dystroglycanopathy type B+++H00593///Limb-girdle muscular dystrophy (LGMD)+++H00120///Muscular dystrophy-dystroglycanopathy type A+++H01959///Muscular dystrophy-dystroglycanopathy type C+++H00590///Congenital muscular dystrophies (CMD/MDC)",null,"R07620///Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027+++R04072///dolichyl-beta-D-mannosyl-phosphate:protein-serine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]+++R11399///dolichyl-beta-D-mannosyl-phosphate:protein-threonine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein]","GO:0016021///integral component of membrane+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0097502///mannosylation+++GO:0030198///extracellular matrix organization+++GO:0035269///protein O-linked mannosylation+++GO:0007275///multicellular organism development+++GO:0006486///protein glycosylation+++GO:1904100///positive regulation of protein O-linked glycosylation+++GO:0005975///carbohydrate metabolic process+++GO:0006493///protein O-linked glycosylation","protein O-mannosyltransferase 1","[POMT1_HUMAN|Reviewed]RecName: Full=Protein O-mannosyl-transferase 1; EC=2.4.1.109; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 1;+++[A0A140VKE0_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 57p {ECO:0000313|EMBL:AEE61277.1};+++[A0A1L6C7Q4_HUMAN|Unreviewed]SubName: Full=Truncated O-mannosyl-transferase 1 variant SV3DEL {ECO:0000313|EMBL:APQ46216.1}; EC=2.4.1.109 {ECO:0000313|EMBL:APQ46216.1};+++[A0A1V1FTP4_HUMAN|Unreviewed]SubName: Full=POMT1 protein {ECO:0000313|EMBL:BAX07485.1};+++[Q5JSZ6_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000390737}; Flags: Fragment;+++[Q5JT02_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000361294}; Flags: Fragment;+++[Q5JT03_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000395060}; Flags: Fragment;+++[Q5JT04_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000405149}; Flags: Fragment;+++[Q5JT05_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000402083}; Flags: Fragment;+++[Q5JT07_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000403736}; Flags: Fragment;"]
[10586,"'MAB21L2'",1080,1521,1422,1341,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0043010///camera-type eye development+++GO:0010172///embryonic body morphogenesis+++GO:0007399///nervous system development+++GO:0001654///eye development+++GO:0008284///positive regulation of cell proliferation","mab-21 like 2","[MB212_HUMAN|Reviewed]RecName: Full=Protein mab-21-like 2;"]
[10587,"'TXNRD2'",437.78,488,452,459.26,"05225///Hepatocellular carcinoma+++05200///Pathways in cancer+++00450///Selenocompound metabolism","H00256///Familial glucocorticoid deficiency (FGD)",null,"R09372///methaneselenol:NADP+ oxidoreductase   2 NADPH + 2 H+ + Methylselenic acid <=> 2 NADP+ + 2 H2O + Methaneselenol+++R03596///hydrogen selenide:NADP+ oxidoreductase   Hydrogen selenide + 3 NADP+ + 3 H2O <=> Selenite + 3 NADPH + 5 H+","GO:0005623///cell+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0050660///flavin adenine dinucleotide binding+++GO:0004791///thioredoxin-disulfide reductase activity+++GO:0009055///electron transfer activity","GO:0034599///cellular response to oxidative stress+++GO:0022900///electron transport chain+++GO:0055114///oxidation-reduction process+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification+++GO:0000305///response to oxygen radical","thioredoxin reductase 2","[TRXR2_HUMAN|Reviewed]RecName: Full=Thioredoxin reductase 2, mitochondrial; EC=1.8.1.9; AltName: Full=Selenoprotein Z; Short=SelZ; AltName: Full=TR-beta; AltName: Full=Thioredoxin reductase TR3; Flags: Precursor;+++[A0A096LNY7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485290}; Flags: Fragment;+++[A0A096LP96_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485466};+++[A0A096LPB7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485499};+++[A0A096LPD9_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485543};+++[A0A096LPH4_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485603};+++[A0A096LPK7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485665};+++[A0A0U1RQX0_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000489208}; Flags: Fragment;+++[A0A182DWF2_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383362};+++[A0A182DWF3_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383363};+++[A4FTY4_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAH99923.1};+++[D3YTF8_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383369};+++[E7EWK1_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000334451};+++[Q17RE6_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAI17355.1};"]
[10588,"'MTHFS'",98,94,97,96.3333333333333,"00670///One carbon pool by folate+++01100///Metabolic pathways",null,null,"R02301///5-Formyltetrahydrofolate cyclo-ligase (ADP-forming)   ATP + Folinic acid + H+ <=> ADP + Orthophosphate + 5,10-Methenyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix","GO:0005542///folic acid binding+++GO:0005524///ATP binding+++GO:0030272///5-formyltetrahydrofolate cyclo-ligase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016874///ligase activity","GO:0006536///glutamate metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0015942///formate metabolic process+++GO:0046655///folic acid metabolic process+++GO:0046657///folic acid catabolic process+++GO:0009396///folic acid-containing compound biosynthetic process+++GO:0035999///tetrahydrofolate interconversion","methenyltetrahydrofolate synthetase","[MTHFS_HUMAN|Reviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase; EC=6.3.3.2; AltName: Full=5,10-methenyl-tetrahydrofolate synthetase; Short=MTHFS; Short=Methenyl-THF synthetase;+++[A0A0U1RQM3_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279};+++[H3BMB9_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454318}; Flags: Fragment;+++[H3BN04_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454626};+++[Q96EE9_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279}; Flags: Fragment;"]
[10589,"'DRAP1'",663,501,564,576,{"$nulls":4},"GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","DR1 associated protein 1","[NC2A_HUMAN|Reviewed]RecName: Full=Dr1-associated corepressor; AltName: Full=Dr1-associated protein 1; AltName: Full=Negative cofactor 2-alpha; Short=NC2-alpha;+++[C9JCC6_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000366190};+++[E9PMW2_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437287};+++[E9PNC7_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437225}; Flags: Fragment;+++[E9PQX9_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000432445};"]
[1059,"'CENPB'",2225,2367,2114,2235.33333333333,{"$nulls":4},"GO:0016604///nuclear body+++GO:0031618///nuclear pericentric heterochromatin+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0005634///nucleus","GO:0003696///satellite DNA binding+++GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0019237///centromeric DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding",null,"centromere protein B","[CENPB_HUMAN|Reviewed]RecName: Full=Major centromere autoantigen B; AltName: Full=Centromere protein B; Short=CENP-B;"]
[10590,"'SCGN'",2,1,3,2,{"$nulls":4},"GO:0030658///transport vesicle membrane+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0098793///presynapse","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0008150///biological_process+++GO:1900271///regulation of long-term synaptic potentiation+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0051480///regulation of cytosolic calcium ion concentration","secretagogin, EF-hand calcium binding protein","[SEGN_HUMAN|Reviewed]RecName: Full=Secretagogin;+++[Q96P10_HUMAN|Unreviewed]SubName: Full=Secretagogin, EF-hand calcium binding protein, isoform CRA_b {ECO:0000313|EMBL:EAW55488.1}; SubName: Full=Setagin {ECO:0000313|EMBL:AAL16052.1};"]
[10591,"'DNPH1'",455,449,447,450.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0070694///deoxyribonucleoside 5'-monophosphate N-glycosidase activity+++GO:0042803///protein homodimerization activity+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0016798///hydrolase activity, acting on glycosyl bonds","GO:0008152///metabolic process+++GO:0009159///deoxyribonucleoside monophosphate catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0009116///nucleoside metabolic process+++GO:0006195///purine nucleotide catabolic process+++GO:0008283///cell proliferation+++GO:0009117///nucleotide metabolic process+++GO:0030307///positive regulation of cell growth","2'-deoxynucleoside 5'-phosphate N-hydrolase 1","[DNPH1_HUMAN|Reviewed]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036, ECO:0000269|PubMed:24260472, ECO:0000269|PubMed:25108359}; AltName: Full=c-Myc-responsive protein RCL {ECO:0000255|HAMAP-Rule:MF_03036};+++[H0Y8X4_HUMAN|Unreviewed]SubName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000313|Ensembl:ENSP00000422440}; Flags: Fragment;"]
[10592,"'SMC2'",347,294,335,325.333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0070062///extracellular exosome+++GO:0005730///nucleolus+++GO:0000228///nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0046982///protein heterodimerization activity","GO:0051301///cell division+++GO:0045132///meiotic chromosome segregation+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0051383///kinetochore organization","structural maintenance of chromosomes 2","[SMC2_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 2; Short=SMC protein 2; Short=SMC-2; AltName: Full=Chromosome-associated protein E; Short=hCAP-E; AltName: Full=XCAP-E homolog;+++[A0A024R158_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[A8K984_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B3KMB1_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B7ZLZ7_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[Q05BV1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH32705.1}; Flags: Fragment;+++[Q05D74_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH17845.1}; Flags: Fragment;+++[Q6IPS5_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH71750.1}; Flags: Fragment;+++[Q7Z2X1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH55081.1}; Flags: Fragment;"]
[10594,"'PRPF8'",7622,9456,8114,8397.33333333333,"03040///Spliceosome","H00527///Retinitis pigmentosa (RP)","M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005682///U5 snRNP+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0016020///membrane","GO:0000386///second spliceosomal transesterification activity+++GO:0097157///pre-mRNA intronic binding+++GO:0030623///U5 snRNA binding+++GO:0003723///RNA binding+++GO:0030620///U2 snRNA binding+++GO:0017070///U6 snRNA binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0030619///U1 snRNA binding+++GO:0005515///protein binding","GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0006397///mRNA processing+++GO:0071356///cellular response to tumor necrosis factor+++GO:0008380///RNA splicing","pre-mRNA processing factor 8","[PRP8_HUMAN|Reviewed]RecName: Full=Pre-mRNA-processing-splicing factor 8; AltName: Full=220 kDa U5 snRNP-specific protein; AltName: Full=PRP8 homolog; AltName: Full=Splicing factor Prp8; AltName: Full=p220;+++[I3L0J9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000458151}; Flags: Fragment;+++[I3L1T8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000459095}; Flags: Fragment;+++[I3L3Z8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000460849}; Flags: Fragment;"]
[10595,"'ERN2'",1,2,3,2,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990604///IRE1-TRAF2-ASK1 complex","GO:0000166///nucleotide binding+++GO:0004540///ribonuclease activity+++GO:0004519///endonuclease activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0000287///magnesium ion binding","GO:0006397///mRNA processing+++GO:0007050///cell cycle arrest+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008152///metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0030263///apoptotic chromosome condensation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0007257///activation of JUN kinase activity+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0016075///rRNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis","endoplasmic reticulum to nucleus signaling 2","[ERN2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2; AltName: Full=Endoplasmic reticulum-to-nucleus signaling 2; AltName: Full=Inositol-requiring protein 2; Short=hIRE2p; AltName: Full=Ire1-beta; Short=IRE1b; Includes: RecName: Full=Serine/threonine-protein kinase; EC=2.7.11.1; Includes: RecName: Full=Endoribonuclease; EC=3.1.26.-; Flags: Precursor;+++[A5YM46_HUMAN|Unreviewed]SubName: Full=ERN2 protein {ECO:0000313|EMBL:ABQ59030.1};+++[A5YM65_HUMAN|Unreviewed]SubName: Full=ERN2 protein {ECO:0000313|EMBL:ABQ59049.1};+++[E7ETG2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000413812};+++[H3BSU1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000456866}; Flags: Fragment;+++[H3BTW8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000457361};+++[H3BUU2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000457796};"]
[10597,"'TRAPPC2B'",20.66,26.58,37.87,28.37,null,"H00760///Spondyloepiphyseal dysplasia tarda",null,null,"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0008134///transcription factor binding+++GO:0044325///ion channel binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport","trafficking protein particle complex 2B","[TPC2A_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2; AltName: Full=Sedlin;+++[TPC2B_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2B; AltName: Full=MBP-1-interacting protein 2A; Short=MIP-2A;+++[TPPC2_BOVIN|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_CANLF|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_PONAB|diamond]RecName: Full=Trafficking protein particle complex subunit 2;"]
[10598,"'AHSA1'",847,807,789,814.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0001671///ATPase activator activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0032781///positive regulation of ATPase activity","activator of HSP90 ATPase activity 1","[AHSA1_HUMAN|Reviewed]RecName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1; Short=AHA1; AltName: Full=p38;+++[G3V3W9_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451467};+++[G3V438_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451569}; Flags: Fragment;+++[H0YJ63_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000450890}; Flags: Fragment;+++[H0YJG7_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451475}; Flags: Fragment;+++[H0YJU2_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000452127}; Flags: Fragment;"]
[1060,"'CENPC'",126,91,108,108.333333333333,{"$nulls":4},"GO:0031618///nuclear pericentric heterochromatin+++GO:0000776///kinetochore+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0090543///Flemming body+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0030496///midbody+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0032154///cleavage furrow","GO:0003677///DNA binding+++GO:0019237///centromeric DNA binding","GO:0007059///chromosome segregation+++GO:0000278///mitotic cell cycle+++GO:0051455///attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation+++GO:0051382///kinetochore assembly+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division","centromere protein C","[CENPC_HUMAN|Reviewed]RecName: Full=Centromere protein C; Short=CENP-C; AltName: Full=Centromere autoantigen C; AltName: Full=Centromere protein C 1; Short=CENP-C 1; AltName: Full=Interphase centromere complex protein 7;"]
[10600,"'USP16'",300,303,256,286.333333333333,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0035578///azurophil granule lumen+++GO:0070062///extracellular exosome+++GO:0044297///cell body+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0002199///zona pellucida receptor complex+++GO:0045111///intermediate filament cytoskeleton+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005874///microtubule+++GO:0034774///secretory granule lumen","GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0042393///histone binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0044183///protein binding involved in protein folding+++GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0043130///ubiquitin binding+++GO:0045296///cadherin binding+++GO:0005524///ATP binding+++GO:0042623///ATPase activity, coupled+++GO:0004197///cysteine-type endopeptidase activity+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0016578///histone deubiquitination+++GO:0045901///positive regulation of translational elongation+++GO:0000278///mitotic cell cycle+++GO:0046931///pore complex assembly+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061077///chaperone-mediated protein folding+++GO:0051726///regulation of cell cycle+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0051289///protein homotetramerization+++GO:0006351///transcription, DNA-templated+++GO:0043312///neutrophil degranulation+++GO:0051301///cell division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006458///'de novo' protein folding+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0140014///mitotic nuclear division+++GO:0016579///protein deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0007339///binding of sperm to zona pellucida","ubiquitin specific peptidase 16","[UBP16_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; EC=3.4.19.12 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Deubiquitinating enzyme 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin thioesterase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin-processing protease UBP-M; AltName: Full=Ubiquitin-specific-processing protease 16 {ECO:0000255|HAMAP-Rule:MF_03062};"]
[10602,"'CDC42EP3'",1150,1001,1151,1100.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system","GO:0005515///protein binding+++GO:0005519///cytoskeletal regulatory protein binding+++GO:0017049///GTP-Rho binding","GO:0008360///regulation of cell shape+++GO:0007165///signal transduction+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization","CDC42 effector protein 3","[BORG2_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 3; AltName: Full=Binder of Rho GTPases 2; AltName: Full=MSE55-related Cdc42-binding protein;+++[C9J7F7_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000398062}; Flags: Fragment;+++[C9JEZ4_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000403298}; Flags: Fragment;+++[C9JKW5_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000409147}; Flags: Fragment;"]
[10603,"'SH2B2'",115,107,116,112.666666666667,"04910///Insulin signaling pathway+++04722///Neurotrophin signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0035591///signaling adaptor activity+++GO:0008236///serine-type peptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008269///JAK pathway signal transduction adaptor activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0016787///hydrolase activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0004252///serine-type endopeptidase activity","GO:0009967///positive regulation of signal transduction+++GO:0007165///signal transduction+++GO:0001922///B-1 B cell homeostasis+++GO:0006508///proteolysis+++GO:0007399///nervous system development+++GO:0046578///regulation of Ras protein signal transduction+++GO:0007596///blood coagulation+++GO:0050776///regulation of immune response+++GO:0008286///insulin receptor signaling pathway+++GO:0046425///regulation of JAK-STAT cascade+++GO:0050873///brown fat cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0019222///regulation of metabolic process","SH2B adaptor protein 2","[SH2B2_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 2; AltName: Full=Adapter protein with pleckstrin homology and Src homology 2 domains; AltName: Full=SH2 and PH domain-containing adapter protein APS;+++[A0A087X016_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000483034};+++[C9JK89_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000401883}; Flags: Fragment;+++[Q15098_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59997.1}; Flags: Fragment;+++[Q6LDS3_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59995.1}; Flags: Fragment;"]
[10605,"'PAIP1'",998,851,887,912,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0008494///translation activator activity+++GO:0003723///RNA binding","GO:0048255///mRNA stabilization+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0045727///positive regulation of translation+++GO:0006417///regulation of translation","poly(A) binding protein interacting protein 1","[PAIP1_HUMAN|Reviewed]RecName: Full=Polyadenylate-binding protein-interacting protein 1; Short=PABP-interacting protein 1; Short=PAIP-1; Short=Poly(A)-binding protein-interacting protein 1;+++[A0A024R094_HUMAN|Unreviewed]SubName: Full=Poly(A) binding protein interacting protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW56068.1};+++[A0A1D5RMS4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427410}; Flags: Fragment;+++[D6R9H8_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000422084};+++[D6RD97_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425406}; Flags: Fragment;+++[D6REB4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425084};+++[D6RJ02_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425736}; Flags: Fragment;+++[D6RJF2_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425675}; Flags: Fragment;+++[H0YA44_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000426089}; Flags: Fragment;"]
[10606,"'PAICS'",2284,2142.05,2181,2202.35,"01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites",null,"M00048///Inosine monophosphate biosynthesis, PRPP + glutamine => IMP","R04209///1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase   1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2+++R04591///1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)   ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0045296///cadherin binding+++GO:0043727///5-amino-4-imidazole carboxylate lyase activity+++GO:0003824///catalytic activity+++GO:0004638///phosphoribosylaminoimidazole carboxylase activity+++GO:0016831///carboxy-lyase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity+++GO:0000166///nucleotide binding+++GO:0016829///lyase activity+++GO:0016874///ligase activity+++GO:0005515///protein binding","GO:0009113///purine nucleobase biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0008152///metabolic process+++GO:0006189///'de novo' IMP biosynthetic process","phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase","[PUR6_HUMAN|Reviewed]RecName: Full=Multifunctional protein ADE2; Includes: RecName: Full=Phosphoribosylaminoimidazole-succinocarboxamide synthase; EC=6.3.2.6; AltName: Full=SAICAR synthetase; Includes: RecName: Full=Phosphoribosylaminoimidazole carboxylase; EC=4.1.1.21; AltName: Full=AIR carboxylase; Short=AIRC;+++[A0A024RD93_HUMAN|Unreviewed]SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_c {ECO:0000313|EMBL:EAX05492.1};+++[D6RF62_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424907}; SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_b {ECO:0000313|EMBL:EAX05490.1};+++[E9PBS1_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424053}; Flags: Fragment;"]
[10607,"'TBL3'",707,818,724,749.666666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0005634///nucleus","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","transducin beta like 3","[TBL3_HUMAN|Reviewed]RecName: Full=Transducin beta-like protein 3; AltName: Full=WD repeat-containing protein SAZD;+++[A0A087WYP7_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000481995};+++[A0JLS5_HUMAN|Unreviewed]SubName: Full=TBL3 protein {ECO:0000313|EMBL:AAH07620.1}; Flags: Fragment;+++[H3BN88_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000454735};+++[J3KNP2_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000331815}; Flags: Fragment;"]
[10608,"'MXD4'",3798,3934,3783,3838.33333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008285///negative regulation of cell proliferation+++GO:0000122///negative regulation of transcription by RNA polymerase II","MAX dimerization protein 4","[MAD4_HUMAN|Reviewed]RecName: Full=Max dimerization protein 4; Short=Max dimerizer 4; AltName: Full=Class C basic helix-loop-helix protein 12; Short=bHLHc12; AltName: Full=Max-associated protein 4; AltName: Full=Max-interacting transcriptional repressor MAD4;+++[D3DVQ5_HUMAN|Unreviewed]SubName: Full=MAX dimerization protein 4, isoform CRA_e {ECO:0000313|EMBL:EAW82535.1};+++[D6RGV1_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000421209};+++[H0Y8Z5_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000422660}; Flags: Fragment;+++[Q7Z2R2_HUMAN|Unreviewed]SubName: Full=MSTP149 {ECO:0000313|EMBL:AAQ13695.1};"]
[10609,"'P3H4'",2427.01,2082.99,2173.98,2227.99333333333,{"$nulls":4},"GO:1902494///catalytic complex+++GO:0000794///condensed nuclear chromosome+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0000795///synaptonemal complex",null,"GO:0032964///collagen biosynthetic process+++GO:0030199///collagen fibril organization+++GO:0046849///bone remodeling+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0007130///synaptonemal complex assembly","prolyl 3-hydroxylase family member 4 (non-enzymatic)","[SC65_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653}; AltName: Full=Leprecan-like protein 4; AltName: Full=Nucleolar autoantigen No55 {ECO:0000303|PubMed:10952778, ECO:0000303|PubMed:8862517}; AltName: Full=Prolyl 3-hydroxylase family member 4 {ECO:0000312|HGNC:HGNC:16946}; AltName: Full=Synaptonemal complex protein SC65 {ECO:0000250|UniProtKB:Q64375}; Flags: Precursor;+++[H0YED7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000435615}; Flags: Fragment;+++[K7EJ03_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000464968}; Flags: Fragment;+++[K7ERA3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000468174}; Flags: Fragment;"]
[10610,"'ST6GALNAC2'",385,683,497,521.666666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008373///sialyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0016740///transferase activity","GO:0006486///protein glycosylation+++GO:0016266///O-glycan processing+++GO:0006493///protein O-linked glycosylation+++GO:0097503///sialylation+++GO:1990743///protein sialylation","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2","[SIA7B_HUMAN|Reviewed]RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; EC=2.4.99.3 {ECO:0000269|PubMed:10742600, ECO:0000269|PubMed:29251719}; AltName: Full=GalNAc alpha-2,6-sialyltransferase II; AltName: Full=ST6GalNAc II {ECO:0000303|PubMed:10742600}; Short=ST6GalNAcII {ECO:0000303|PubMed:29251719}; AltName: Full=SThM; AltName: Full=Sialyltransferase 7B; Short=SIAT7-B;+++[A0A024R8M1_HUMAN|Unreviewed]SubName: Full=ST6 (Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, isoform CRA_b {ECO:0000313|EMBL:EAW89418.1};+++[K7EIW2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000464915}; Flags: Fragment;+++[K7EKT8_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000465778};+++[K7EMI2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466513};+++[K7EMM1_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466560}; Flags: Fragment;"]
[10611,"'PDLIM5'",7332.97,6646.07,6557.2,6845.41333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005913///cell-cell adherens junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0098641///cadherin binding involved in cell-cell adhesion","GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0098609///cell-cell adhesion+++GO:0051963///regulation of synapse assembly+++GO:0061001///regulation of dendritic spine morphogenesis","PDZ and LIM domain 5","[PDLI5_HUMAN|Reviewed]RecName: Full=PDZ and LIM domain protein 5; AltName: Full=Enigma homolog; AltName: Full=Enigma-like PDZ and LIM domains protein;+++[A0A024RDE8_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain 5, isoform CRA_c {ECO:0000313|EMBL:EAX06057.1};+++[A0A0A0MSP3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000398469};+++[A0A0D9SFR4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486834}; Flags: Fragment;+++[A0A0D9SFW3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486938};+++[B7Z481_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54018, highly similar to PDZ and LIM domain protein 5 {ECO:0000313|EMBL:BAH12467.1};+++[B7Z8X5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61541, highly similar to Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 2, mRNA {ECO:0000313|EMBL:BAH14111.1};+++[D6RAA1_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000423009};+++[D6RGG6_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000426379};+++[H0Y8Y3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422528}; Flags: Fragment;+++[H0Y929_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422833}; Flags: Fragment;+++[H0YBI4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000429577}; Flags: Fragment;+++[Q4W5K9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LIM {ECO:0000313|EMBL:AAY40898.1}; Flags: Fragment;"]
[10612,"'TRIM3'",196,180,182,186,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005769///early endosome+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0030425///dendrite","GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination","tripartite motif containing 3","[TRIM3_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 3; AltName: Full=Brain-expressed RING finger protein; AltName: Full=RING finger protein 22; AltName: Full=RING finger protein 97;+++[A0A1W2PPI7_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000491359};+++[B7Z5Y8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56028, highly similar to Tripartite motif-containing protein 3 {ECO:0000313|EMBL:BAH13074.1};+++[D3DQT3_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_d {ECO:0000313|EMBL:EAW68713.1}; Flags: Fragment;+++[D3DQT4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_f {ECO:0000313|EMBL:EAW68716.1}; Flags: Fragment;+++[E9PMK8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000433070}; Flags: Fragment;+++[E9PMW5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000437283}; Flags: Fragment;+++[L8EAL7_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM3 {ECO:0000313|EMBL:CCQ43796.1};"]
[10613,"'ERLIN1'",462,463,483,469.333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0015485///cholesterol binding","GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0008202///steroid metabolic process+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0032933///SREBP signaling pathway+++GO:0055085///transmembrane transport","ER lipid raft associated 1","[ERLN1_HUMAN|Reviewed]RecName: Full=Erlin-1; AltName: Full=Endoplasmic reticulum lipid raft-associated protein 1; AltName: Full=Protein KE04; AltName: Full=Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; Short=SPFH domain-containing protein 1;+++[B0QZ43_HUMAN|Unreviewed]SubName: Full=Erlin-1 {ECO:0000313|Ensembl:ENSP00000359436}; Flags: Fragment;+++[D3DR65_HUMAN|Unreviewed]SubName: Full=SPFH domain family, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW49847.1};"]
[10614,"'HEXIM1'",601,562,519,560.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0097322///7SK snRNA binding+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0017069///snRNA binding","GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045087///innate immune response+++GO:0007507///heart development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0002376///immune system process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002218///activation of innate immune response","hexamethylene bisacetamide inducible 1","[HEXI1_HUMAN|Reviewed]RecName: Full=Protein HEXIM1; AltName: Full=Cardiac lineage protein 1; AltName: Full=Estrogen down-regulated gene 1 protein; AltName: Full=Hexamethylene bis-acetamide-inducible protein 1; AltName: Full=Menage a quatre protein 1;+++[Q7L853_HUMAN|Unreviewed]SubName: Full=EDG1 {ECO:0000313|EMBL:AAK01993.1}; Flags: Fragment;"]
[10615,"'SPAG5'",28,20,34,27.3333333333333,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0034451///centriolar satellite+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton+++GO:0005694///chromosome+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0000777///condensed chromosome kinetochore+++GO:0005819///spindle+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0007059///chromosome segregation+++GO:0032388///positive regulation of intracellular transport+++GO:0007049///cell cycle+++GO:0000070///mitotic sister chromatid segregation+++GO:0090235///regulation of metaphase plate congression+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0007051///spindle organization+++GO:1905832///positive regulation of spindle assembly+++GO:0071539///protein localization to centrosome","sperm associated antigen 5","[SPAG5_HUMAN|Reviewed]RecName: Full=Sperm-associated antigen 5; AltName: Full=Astrin; AltName: Full=Deepest; AltName: Full=Mitotic spindle-associated protein p126; Short=MAP126;+++[A4FUA2_HUMAN|Unreviewed]SubName: Full=SPAG5 protein {ECO:0000313|EMBL:AAI13056.1}; Flags: Fragment;+++[F5GZT2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000444223}; Flags: Fragment;+++[J3KSV2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000462663};+++[J3KTQ0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000463095}; Flags: Fragment;+++[J3QRL6_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464280}; Flags: Fragment;+++[J3QRV8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464400};+++[J3QS12_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464474}; Flags: Fragment;+++[K7ELC8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466021}; Flags: Fragment;+++[K7ELG0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466061}; Flags: Fragment;"]
[10616,"'RBCK1'",1599,1767,1608,1658,"04217///Necroptosis+++04621///NOD-like receptor signaling pathway","H01744///Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis",null,null,"GO:0005829///cytosol+++GO:0071797///LUBAC complex","GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0060546///negative regulation of necroptotic process+++GO:0000209///protein polyubiquitination+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0097039///protein linear polyubiquitination+++GO:0050852///T cell receptor signaling pathway+++GO:0016032///viral process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling","RANBP2-type and C3HC4-type zinc finger containing 1","[HOIL1_HUMAN|Reviewed]RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1; EC=2.3.2.31 {ECO:0000269|PubMed:12629548}; AltName: Full=HBV-associated factor 4; AltName: Full=Heme-oxidized IRP2 ubiquitin ligase 1; Short=HOIL-1; AltName: Full=Hepatitis B virus X-associated protein 4; AltName: Full=RING finger protein 54; AltName: Full=RING-type E3 ubiquitin transferase HOIL-1 {ECO:0000305}; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 3;+++[A6PVJ5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000383106};+++[A6PVJ6_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000417173};+++[A6PVJ7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387799}; Flags: Fragment;+++[A6PVK0_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_b {ECO:0000313|EMBL:EAX10674.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371616};+++[B4DML5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405288}; SubName: Full=cDNA FLJ60704, highly similar to RanBP-type and C3HC4-type zincfinger-containing protein 1 {ECO:0000313|EMBL:BAG59927.1};+++[G3XAG9_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_d {ECO:0000313|EMBL:EAX10676.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371649};+++[H0Y4S7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000393841}; Flags: Fragment;+++[Q5JWR1_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000415080}; Flags: Fragment;"]
[10617,"'STAMBP'",1026,1092,944,1020.66666666667,"04144///Endocytosis","H01872///Microcephaly-capillary malformation syndrome",null,null,"GO:0005634///nucleus+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0070062///extracellular exosome+++GO:0032154///cleavage furrow+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008237///metallopeptidase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0019904///protein domain specific binding","GO:0046580///negative regulation of Ras protein signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0000281///mitotic cytokinesis+++GO:0007259///JAK-STAT cascade+++GO:0070536///protein K63-linked deubiquitination+++GO:0016579///protein deubiquitination+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0006508///proteolysis","STAM binding protein","[STABP_HUMAN|Reviewed]RecName: Full=STAM-binding protein; EC=3.4.19.-; AltName: Full=Associated molecule with the SH3 domain of STAM; AltName: Full=Endosome-associated ubiquitin isopeptidase;+++[A0A140VK54_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 54 {ECO:0000313|EMBL:AEE61191.1};+++[C9JEK5_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000390921}; Flags: Fragment;+++[C9JK83_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413874}; Flags: Fragment;+++[C9JZ93_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413291}; Flags: Fragment;+++[F5H5B9_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000443502};+++[L8ECD1_HUMAN|Unreviewed]SubName: Full=Alternative protein STAMBP {ECO:0000313|EMBL:CCQ43357.1};"]
[10618,"'TGOLN2'",2911.7,2731,2845.2,2829.3,"04137///Mitophagy - animal+++00830///Retinol metabolism+++04140///Autophagy - animal",null,null,"R07163///all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductas all-trans-13,14-Dihydroretinol + Acceptor <=> Retinol + Reduced acceptor","GO:0030140///trans-Golgi network transport vesicle+++GO:0005788///endoplasmic reticulum lumen+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0030133///transport vesicle+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0061024///membrane organization+++GO:0044267///cellular protein metabolic process","trans-golgi network protein 2","[TGON2_HUMAN|Reviewed]RecName: Full=Trans-Golgi network integral membrane protein 2; AltName: Full=TGN38 homolog; AltName: Full=TGN46; AltName: Full=TGN48; AltName: Full=Trans-Golgi network protein TGN51; Flags: Precursor;"]
[1062,"'CENPE'",5,12,13,10,null,"H00269///Primary microcephaly (MCPH)",null,null,"GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:0005828///kinetochore microtubule+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0000775///chromosome, centromeric region+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:1990023///mitotic spindle midzone+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0000779///condensed chromosome, centromeric region+++GO:0005874///microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005694///chromosome","GO:0005515///protein binding+++GO:0043515///kinetochore binding+++GO:0016887///ATPase activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0003777///microtubule motor activity","GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0045860///positive regulation of protein kinase activity+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0007275///multicellular organism development+++GO:0099606///microtubule plus-end directed mitotic chromosome migration+++GO:0099607///lateral attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division+++GO:0007059///chromosome segregation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0007049///cell cycle+++GO:0051382///kinetochore assembly+++GO:0007018///microtubule-based movement+++GO:0000278///mitotic cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore","centromere protein E","[CENPE_HUMAN|Reviewed]RecName: Full=Centromere-associated protein E; AltName: Full=Centromere protein E; Short=CENP-E; AltName: Full=Kinesin-7 {ECO:0000303|PubMed:25908662}; AltName: Full=Kinesin-related protein CENPE; Flags: Precursor;+++[A0A087X0P0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000483542};+++[D6RBW0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000423981}; Flags: Fragment;+++[D6RHK2_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000426023}; Flags: Fragment;"]
[10620,"'ARID3B'",132,166,151,149.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II","AT-rich interaction domain 3B","[ARI3B_HUMAN|Reviewed]RecName: Full=AT-rich interactive domain-containing protein 3B; Short=ARID domain-containing protein 3B; AltName: Full=Bright and dead ringer protein; AltName: Full=Bright-like protein;+++[H3BQ92_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 3B {ECO:0000313|Ensembl:ENSP00000455668}; Flags: Fragment;"]
[10621,"'POLR3F'",110,77,101,96,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding","GO:0002376///immune system process+++GO:0045089///positive regulation of innate immune response+++GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III","RNA polymerase III subunit F","[RPC6_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6; Short=RNA polymerase III subunit C6; AltName: Full=DNA-directed RNA polymerase III subunit F; AltName: Full=RNA polymerase III 39 kDa subunit; Short=RPC39;+++[L8EAI3_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3F {ECO:0000313|EMBL:CCQ43358.1};+++[Q05DB8_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763}; Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};"]
[10622,"'POLR3G'",19,23,29,23.6666666666667,"01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++05169///Epstein-Barr virus infection+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA","GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0002376///immune system process+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0045089///positive regulation of innate immune response+++GO:0008283///cell proliferation","RNA polymerase III subunit G","[RPC7_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC7; Short=RNA polymerase III subunit C7; AltName: Full=DNA-directed RNA polymerase III subunit G; AltName: Full=RNA polymerase III 32 kDa apha subunit; Short=RPC32-alpha {ECO:0000303|PubMed:20154270}; AltName: Full=RNA polymerase III 32 kDa subunit; Short=RPC32;+++[A0A024RAM1_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit {ECO:0000256|PIRNR:PIRNR000777};+++[D6R921_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422164}; Flags: Fragment;+++[D6R9U7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422892}; Flags: Fragment;+++[D6REQ0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000424970}; Flags: Fragment;+++[D6RIT0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000427412}; Flags: Fragment;+++[D6RJH6_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000425617};+++[L8E8B4_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3G {ECO:0000313|EMBL:CCQ43359.1};"]
[10623,"'POLR3C'",428,393,357,392.666666666667,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++00240///Pyrimidine metabolism+++03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex","GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003697///single-stranded DNA binding","GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0006351///transcription, DNA-templated+++GO:0051607///defense response to virus+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0002376///immune system process+++GO:0006383///transcription by RNA polymerase III","RNA polymerase III subunit C","[RPC3_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC3; Short=RNA polymerase III subunit C3; AltName: Full=DNA-directed RNA polymerase III subunit C; AltName: Full=RNA polymerase III 62 kDa subunit; Short=RPC62;+++[A0A024R4C1_HUMAN|Unreviewed]SubName: Full=Polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b {ECO:0000313|EMBL:EAW71436.1};+++[E9PHH9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000313|Ensembl:ENSP00000358300};+++[Q9BT08_HUMAN|Unreviewed]SubName: Full=POLR3C protein {ECO:0000313|EMBL:AAH04424.1};"]
[10625,"'IVNS1ABP'",6559,5210,5660,5809.66666666667,"05164///Influenza A",{"$nulls":3},"GO:0043025///neuronal cell body+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005743///mitochondrial inner membrane+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity","GO:0042493///response to drug+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0009615///response to virus+++GO:0006383///transcription by RNA polymerase III+++GO:0008380///RNA splicing+++GO:0055114///oxidation-reduction process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033194///response to hydroperoxide+++GO:0014070///response to organic cyclic compound+++GO:0016032///viral process","influenza virus NS1A binding protein",{"$cut":{"chars":32759,"head":"[NS1BP_HUMAN|Reviewed]RecName: Full=Influenza virus NS1A-binding protein; Short=NS1-BP; Short=NS1-binding protein {ECO:0000303|PubMed:9696811}; AltName: Full=Aryl hydrocarbon receptor-associated protein 3 {ECO:0000303|PubMed:16582008}; AltName: Full=Kelch-like protein 39 {ECO:0000303|PubMed:25619834};+++[A0A023I7N5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q5S8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q700_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q7R1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q875_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QC18_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QFT1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QG73_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QHN5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKB4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKQ2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QL98_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QMR7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QR60_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QRY9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QST8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QUI7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QW57_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QWQ3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXG8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXJ5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXT5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QYN1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QZ36_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0"}}]
[10626,"'TRIM16'",255.09,280.71,244.33,260.043333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016605///PML body","GO:0003676///nucleic acid binding+++GO:0032089///NACHT domain binding+++GO:0016740///transferase activity+++GO:0019966///interleukin-1 binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032526///response to retinoic acid+++GO:0060416///response to growth hormone+++GO:0043966///histone H3 acetylation+++GO:0046683///response to organophosphorus+++GO:0045618///positive regulation of keratinocyte differentiation","tripartite motif containing 16","[TRI16_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 16; AltName: Full=Estrogen-responsive B box protein;+++[B3KP96_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31464 fis, clone NT2NE2001337, highly similar to Tripartite motif-containing protein 16 {ECO:0000313|EMBL:BAG51608.1};+++[J3QKY5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463293}; Flags: Fragment;+++[J3QL38_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463360}; Flags: Fragment;+++[J3QLP0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463639};+++[J3QR69_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000464072}; Flags: Fragment;+++[K7EJH2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465169}; Flags: Fragment;+++[K7EL43_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465907}; Flags: Fragment;+++[K7ENN8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000467031}; Flags: Fragment;"]
[10627,"'MYL12A'",4266,2908,3177,3450.33333333333,"04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0016459///myosin complex","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0070527///platelet aggregation","myosin light chain 12A","[ML12A_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12A; AltName: Full=Epididymis secretory protein Li 24; Short=HEL-S-24; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3;+++[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;+++[J3KT92_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000462865}; Flags: Fragment;+++[J3KTJ1_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000463009}; Flags: Fragment;+++[J3QRS3_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000464359}; SubName: Full=Myosin regulatory light chain MRCL3, isoform CRA_b {ECO:0000313|EMBL:EAX01679.1};"]
[10628,"'TXNIP'",610,556,555,573.666666666667,"04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005758///mitochondrial intermembrane space+++GO:0005737///cytoplasm","GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0051782///negative regulation of cell division+++GO:0042127///regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0030216///keratinocyte differentiation+++GO:0006979///response to oxidative stress+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0043086///negative regulation of catalytic activity+++GO:0006606///protein import into nucleus+++GO:0051592///response to calcium ion+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0009612///response to mechanical stimulus+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0042542///response to hydrogen peroxide+++GO:0071228///cellular response to tumor cell","thioredoxin interacting protein","[TXNIP_HUMAN|Reviewed]RecName: Full=Thioredoxin-interacting protein; AltName: Full=Thioredoxin-binding protein 2; AltName: Full=Vitamin D3 up-regulated protein 1;+++[A0A024R4B7_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAW71411.1};+++[B1ALI9_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein {ECO:0000313|EMBL:CAI22352.1}; Flags: Fragment;+++[L8E7V6_HUMAN|Unreviewed]SubName: Full=Alternative protein TXNIP {ECO:0000313|EMBL:CCQ43360.1};"]
[10629,"'TAF6L'",264,271,245,260,"05168///Herpes simplex infection+++03022///Basal transcription factors","H01879///Wiedemann-Steiner syndrome",null,null,"GO:0005669///transcription factor TFIID complex+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0046695///SLIK (SAGA-like) complex+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0000118///histone deacetylase complex","GO:0003713///transcription coactivator activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0004402///histone acetyltransferase activity","GO:0043966///histone H3 acetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006338///chromatin remodeling+++GO:0006366///transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006352///DNA-templated transcription, initiation+++GO:0006325///chromatin organization","TATA-box binding protein associated factor 6 like","[TAF6L_HUMAN|Reviewed]RecName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; AltName: Full=PCAF-associated factor 65-alpha; Short=PAF65-alpha;+++[A0A024R5A7_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_a {ECO:0000313|EMBL:EAW74094.1};+++[A8K0D4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78693, highly similar to Homo sapiens TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa (TAF6L), mRNA {ECO:0000313|EMBL:BAF82188.1};+++[B4DVM4_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW74095.1}; SubName: Full=cDNA FLJ57614, highly similar to TAF6-like RNA polymerase IIp300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|EMBL:BAG62736.1};+++[E9PK90_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435443};+++[E9PLV8_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435116}; Flags: Fragment;+++[E9PP94_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000434662}; Flags: Fragment;"]
[1063,"'CENPF'",79,77,63,73,null,"H01814///Stromme syndrome",null,null,"GO:0005930///axoneme+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0045120///pronucleus+++GO:0016363///nuclear matrix+++GO:0000776///kinetochore+++GO:0005635///nuclear envelope+++GO:0097539///ciliary transition fiber+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0030496///midbody+++GO:0005694///chromosome+++GO:0000940///condensed chromosome outer kinetochore+++GO:0000922///spindle pole+++GO:0000777///condensed chromosome kinetochore+++GO:0000775///chromosome, centromeric region","GO:0042803///protein homodimerization activity+++GO:0070840///dynein complex binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding","GO:0021591///ventricular system development+++GO:0001822///kidney development+++GO:0030154///cell differentiation+++GO:0007059///chromosome segregation+++GO:0007517///muscle organ development+++GO:0016202///regulation of striated muscle tissue development+++GO:0051310///metaphase plate congression+++GO:0042493///response to drug+++GO:0000278///mitotic cell cycle+++GO:0051301///cell division+++GO:0015031///protein transport+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0051382///kinetochore assembly+++GO:0071897///DNA biosynthetic process","centromere protein F","[CENPF_HUMAN|Reviewed]RecName: Full=Centromere protein F; Short=CENP-F; AltName: Full=AH antigen; AltName: Full=Kinetochore protein CENPF; AltName: Full=Mitosin; Flags: Precursor;+++[A0A087WTY4_HUMAN|Unreviewed]SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSP00000478221};"]
[10630,"'PDPN'",8214,8614,7949,8259,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016323///basolateral plasma membrane+++GO:0071437///invadopodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0031528///microvillus membrane+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0061851///leading edge of lamellipodium+++GO:0001726///ruffle+++GO:0016324///apical plasma membrane+++GO:0031527///filopodium membrane+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0097197///tetraspanin-enriched microdomain+++GO:0045121///membrane raft+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0019956///chemokine binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005372///water transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0051087///chaperone binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity","GO:0044319///wound healing, spreading of cells+++GO:1901731///positive regulation of platelet aggregation+++GO:0001946///lymphangiogenesis+++GO:0060838///lymphatic endothelial cell fate commitment+++GO:0000902///cell morphogenesis+++GO:0003333///amino acid transmembrane transport+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0006833///water transport+++GO:0008360///regulation of cell shape+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:1904328///regulation of myofibroblast contraction+++GO:0008285///negative regulation of cell proliferation+++GO:0051272///positive regulation of cellular component movement+++GO:0015884///folic acid transport+++GO:0030335///positive regulation of cell migration+++GO:0070252///actin-mediated cell contraction+++GO:0030324///lung development+++GO:2000392///regulation of lamellipodium morphogenesis+++GO:0048535///lymph node development+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:1905863///invadopodium organization+++GO:0006865///amino acid transport+++GO:0043066///negative regulation of apoptotic process+++GO:0030168///platelet activation","podoplanin","[PDPN_HUMAN|Reviewed]RecName: Full=Podoplanin {ECO:0000303|Ref.9}; AltName: Full=Aggrus {ECO:0000303|Ref.3}; AltName: Full=Glycoprotein 36; Short=Gp36 {ECO:0000303|PubMed:10393083}; AltName: Full=PA2.26 antigen {ECO:0000303|PubMed:15515019}; AltName: Full=T1-alpha {ECO:0000250|UniProtKB:Q64294}; Short=T1A {ECO:0000250|UniProtKB:Q64294}; Contains: RecName: Full=29kDa cytosolic podoplanin intracellular domain {ECO:0000303|PubMed:24275092}; Short=PICD {ECO:0000303|PubMed:24275092}; Flags: Precursor;+++[D6RH07_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426210};+++[E7ETC6_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000422977};+++[H0Y8Q3_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000421742}; Flags: Fragment;+++[H0YA72_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426302};"]
[10631,"'POSTN'",1182,805,1381,1122.66666666667,{"$nulls":4},"GO:0005802///trans-Golgi network+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005615///extracellular space+++GO:0031594///neuromuscular junction+++GO:0062023///collagen-containing extracellular matrix","GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0046872///metal ion binding","GO:0071307///cellular response to vitamin K+++GO:0001666///response to hypoxia+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0009888///tissue development+++GO:0001501///skeletal system development+++GO:1904209///positive regulation of chemokine (C-C motif) ligand 2 secretion+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:0014850///response to muscle activity+++GO:1990138///neuron projection extension+++GO:0032355///response to estradiol+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030198///extracellular matrix organization+++GO:0008593///regulation of Notch signaling pathway+++GO:0042060///wound healing+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0007155///cell adhesion+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1990523///bone regeneration+++GO:0009612///response to mechanical stimulus+++GO:0003073///regulation of systemic arterial blood pressure","periostin","[POSTN_HUMAN|Reviewed]RecName: Full=Periostin; Short=PN; AltName: Full=Osteoblast-specific factor 2; Short=OSF-2; Flags: Precursor;+++[A0A024RDS2_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_c {ECO:0000313|EMBL:EAX08594.1};+++[A0A024RDT5_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_a {ECO:0000313|EMBL:EAX08591.1};+++[B1ALD9_HUMAN|Unreviewed]SubName: Full=Periostin {ECO:0000313|Ensembl:ENSP00000369073};"]
[10632,"'ATP5MG'",1450,1314,1322,1362,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane","GO:0015078///proton transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism","GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0015986///ATP synthesis coupled proton transport+++GO:0006811///ion transport","ATP synthase membrane subunit g","[ATP5L_HUMAN|Reviewed]RecName: Full=ATP synthase subunit g, mitochondrial {ECO:0000305}; Short=ATPase subunit g; AltName: Full=ATP synthase membrane subunit g {ECO:0000305};+++[E9PN17_HUMAN|Unreviewed]SubName: Full=ATP synthase membrane subunit g {ECO:0000313|Ensembl:ENSP00000434865};"]
[10633,"'RASL10A'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction","RAS like family 10 member A","[RSLAA_HUMAN|Reviewed]RecName: Full=Ras-like protein family member 10A; AltName: Full=Ras-like protein RRP22; AltName: Full=Ras-related protein on chromosome 22; Flags: Precursor;+++[A0A024R1C8_HUMAN|Unreviewed]SubName: Full=RAS-related on chromosome 22, isoform CRA_a {ECO:0000313|EMBL:EAW59797.1};+++[L8E9A0_HUMAN|Unreviewed]SubName: Full=Alternative protein RASL10A {ECO:0000313|EMBL:CCQ42928.1};"]
[10634,"'GAS2L1'",667,614,564,615,{"$nulls":4},"GO:0005874///microtubule+++GO:0001725///stress fiber+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0046966///thyroid hormone receptor binding","GO:0001578///microtubule bundle formation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0009267///cellular response to starvation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0010629///negative regulation of gene expression+++GO:0051726///regulation of cell cycle+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest","growth arrest specific 2 like 1","[GA2L1_HUMAN|Reviewed]RecName: Full=GAS2-like protein 1; AltName: Full=GAS2-related protein on chromosome 22; AltName: Full=Growth arrest-specific protein 2-like 1;+++[A0A024R1J4_HUMAN|Unreviewed]SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_b {ECO:0000313|EMBL:EAW59794.1};+++[A0A5E8_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000478343}; SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_a {ECO:0000313|EMBL:EAW59788.1}; SubName: Full=cDNA FLJ16435 fis, clone BRACE3020671, highly similar to GAS2-like protein 1 {ECO:0000313|EMBL:BAG53749.1}; SubName: Full=cDNA FLJ36067 fis, clone TESTI2019308, highly similar to GAR22 PROTEIN {ECO:0000313|EMBL:BAC04150.1};+++[C9JFI0_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000395988}; Flags: Fragment;+++[C9JRR6_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000388645}; Flags: Fragment;"]
[10635,"'RAD51AP1'",3,9,11,7.66666666666667,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin","GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0006310///DNA recombination+++GO:0036297///interstrand cross-link repair+++GO:0071479///cellular response to ionizing radiation+++GO:0000724///double-strand break repair via homologous recombination+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006281///DNA repair","RAD51 associated protein 1","[R51A1_HUMAN|Reviewed]RecName: Full=RAD51-associated protein 1; AltName: Full=RAD51-interacting protein;+++[F5H031_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000438422};+++[F5H1Y0_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000446296};+++[F5H4V6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439925};+++[F5H710_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000442890};+++[H0YFK6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439019}; Flags: Fragment;+++[H0YGT5_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000444769}; Flags: Fragment;"]
[10636,"'RGS14'",467,486,413,455.333333333333,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016604///nuclear body+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0043197///dendritic spine+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0000922///spindle pole+++GO:0030425///dendrite+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0032794///GTPase activating protein binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030695///GTPase regulator activity+++GO:0005515///protein binding","GO:0060291///long-term synaptic potentiation+++GO:0051301///cell division+++GO:0006913///nucleocytoplasmic transport+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007616///long-term memory+++GO:0008542///visual learning+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0007612///learning+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0000278///mitotic cell cycle+++GO:0007059///chromosome segregation+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0006979///response to oxidative stress+++GO:0050790///regulation of catalytic activity+++GO:0007165///signal transduction+++GO:0010070///zygote asymmetric cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0009968///negative regulation of signal transduction+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0050769///positive regulation of neurogenesis+++GO:0035556///intracellular signal transduction+++GO:0043407///negative regulation of MAP kinase activity","regulator of G protein signaling 14","[RGS14_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 14; Short=RGS14;+++[A0A024R7N4_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein signalling 14, isoform CRA_a {ECO:0000313|EMBL:EAW85013.1};+++[H0Y8W3_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein-signaling 14 {ECO:0000313|Ensembl:ENSP00000422329}; Flags: Fragment;"]
[10637,"'LEFTY1'",0,0.93,0,0.31,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005160///transforming growth factor beta receptor binding+++GO:0008083///growth factor activity+++GO:0005125///cytokine activity","GO:0060395///SMAD protein signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042981///regulation of apoptotic process+++GO:0003007///heart morphogenesis+++GO:0010469///regulation of signaling receptor activity+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0048468///cell development+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0007368///determination of left/right symmetry+++GO:0007275///multicellular organism development","left-right determination factor 1","[LFTY1_HUMAN|Reviewed]RecName: Full=Left-right determination factor 1; AltName: Full=Left-right determination factor B; AltName: Full=Protein lefty-1; AltName: Full=Protein lefty-B; Flags: Precursor;+++[A0A087WW09_HUMAN|Unreviewed]SubName: Full=Left-right determination factor 1 {ECO:0000313|Ensembl:ENSP00000479837}; Flags: Fragment;"]
[10640,"'EXOC5'",560,485,522,522.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0000145///exocyst+++GO:0030496///midbody+++GO:0005737///cytoplasm","GO:0047485///protein N-terminus binding+++GO:0005515///protein binding+++GO:0017160///Ral GTPase binding","GO:0048873///homeostasis of number of cells within a tissue+++GO:1905515///non-motile cilium assembly+++GO:1904019///epithelial cell apoptotic process+++GO:0001736///establishment of planar polarity+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0048278///vesicle docking+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport","exocyst complex component 5","[EXOC5_HUMAN|Reviewed]RecName: Full=Exocyst complex component 5; AltName: Full=Exocyst complex component Sec10; Short=hSec10;+++[A0A0A0MSI8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000389934};+++[F8W9B8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000342100};+++[G3V377_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000451082};+++[G3V4Z7_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000452084}; Flags: Fragment;"]
[10641,"'NPRL2'",280,346,279,301.666666666667,"04150///mTOR signaling pathway",{"$nulls":3},"GO:1990130///GATOR1 complex+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0042802///identical protein binding+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042562///hormone binding+++GO:0005525///GTP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0017046///peptide hormone binding+++GO:0005096///GTPase activator activity+++GO:0000166///nucleotide binding+++GO:0004383///guanylate cyclase activity+++GO:0001653///peptide receptor activity+++GO:0004672///protein kinase activity+++GO:0016829///lyase activity+++GO:0016941///natriuretic peptide receptor activity","GO:2000785///regulation of autophagosome assembly+++GO:0060348///bone development+++GO:0033673///negative regulation of kinase activity+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:1900194///negative regulation of oocyte maturation+++GO:0022414///reproductive process+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0032007///negative regulation of TOR signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0006995///cellular response to nitrogen starvation+++GO:0034198///cellular response to amino acid starvation+++GO:0051447///negative regulation of meiotic cell cycle+++GO:1903779///regulation of cardiac conduction+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0001503///ossification+++GO:0019934///cGMP-mediated signaling+++GO:0010508///positive regulation of autophagy","NPR2 like, GATOR1 complex subunit","[NPRL2_HUMAN|Reviewed]RecName: Full=GATOR complex protein NPRL2 {ECO:0000305}; AltName: Full=Gene 21 protein {ECO:0000303|Ref.1}; Short=G21 protein {ECO:0000303|Ref.1}; AltName: Full=Nitrogen permease regulator 2-like protein {ECO:0000303|PubMed:11085536}; Short=NPR2-like protein {ECO:0000303|PubMed:11085536}; AltName: Full=Tumor suppressor candidate 4 {ECO:0000303|PubMed:18616680};+++[A6NJF2_HUMAN|Unreviewed]SubName: Full=Natriuretic peptide receptor B/guanylate cyclase B (Atrionatriuretic peptide receptor B) variant 3 {ECO:0000313|EMBL:ACA05922.1};+++[F2Z2R8_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000396172};+++[F2Z3D4_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000412779};+++[H7C056_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000393029}; Flags: Fragment;+++[H7C1A1_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000399204}; Flags: Fragment;+++[H7C1X0_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000402902}; Flags: Fragment;"]
[10642,"'IGF2BP1'",944,961,1016,973.666666666667,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0010494///cytoplasmic stress granule+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003723///RNA binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0003692///left-handed Z-DNA binding+++GO:0042802///identical protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0003729///mRNA binding","GO:0010610///regulation of mRNA stability involved in response to stress+++GO:0097150///neuronal stem cell population maintenance+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0006403///RNA localization+++GO:0002376///immune system process+++GO:0006417///regulation of translation+++GO:0022013///pallium cell proliferation in forebrain+++GO:0017148///negative regulation of translation+++GO:0045087///innate immune response+++GO:0008150///biological_process+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0032479///regulation of type I interferon production+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0043488///regulation of mRNA stability+++GO:0032481///positive regulation of type I interferon production","insulin like growth factor 2 mRNA binding protein 1","[IF2B1_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 1; Short=IGF2 mRNA-binding protein 1; Short=IMP-1; Short=IMP1; AltName: Full=Coding region determinant-binding protein; Short=CRD-BP; AltName: Full=IGF-II mRNA-binding protein 1; AltName: Full=VICKZ family member 1; AltName: Full=Zipcode-binding protein 1; Short=ZBP-1;+++[D3DTW3_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP {ECO:0000313|EMBL:AKM97296.1}; SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94694.1};+++[L8ECD2_HUMAN|Unreviewed]SubName: Full=Alternative protein IGF2BP1 {ECO:0000313|EMBL:CCQ43362.1};"]
[10643,"'IGF2BP3'",684,699,774,719,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0048027///mRNA 5'-UTR binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability+++GO:0051028///mRNA transport+++GO:0017148///negative regulation of translation+++GO:0006412///translation+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0006417///regulation of translation","insulin like growth factor 2 mRNA binding protein 3","[IF2B3_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 3; Short=IGF2 mRNA-binding protein 3; Short=IMP-3; AltName: Full=IGF-II mRNA-binding protein 3; AltName: Full=KH domain-containing protein overexpressed in cancer; Short=hKOC; AltName: Full=VICKZ family member 3;+++[F8WD15_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000395936};"]
[10644,"'IGF2BP2'",1591,1596,1448,1545,null,"H00409///Type II diabetes mellitus",null,null,"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability","insulin like growth factor 2 mRNA binding protein 2","[IF2B2_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 2; Short=IGF2 mRNA-binding protein 2; Short=IMP-2; AltName: Full=Hepatocellular carcinoma autoantigen p62; AltName: Full=IGF-II mRNA-binding protein 2; AltName: Full=VICKZ family member 2;+++[B3FTN5_HUMAN|Unreviewed]SubName: Full=Truncated insulin-like 2 growth factor 2-binding protein 2 {ECO:0000313|EMBL:ACB86628.1};+++[B4DKT5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53054, highly similar to Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|EMBL:BAG59297.1};+++[F8W930_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|Ensembl:ENSP00000410242};"]
[10645,"'CAMKK2'",678,690.89,720.92,696.603333333333,"04140///Autophagy - animal+++04152///AMPK signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04211///Longevity regulating pathway+++05034///Alcoholism",{"$nulls":3},"GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042995///cell projection","GO:0004683///calmodulin-dependent protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005516///calmodulin binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding","GO:0016310///phosphorylation+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0000165///MAPK cascade+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0006468///protein phosphorylation+++GO:0034614///cellular response to reactive oxygen species+++GO:0045859///regulation of protein kinase activity+++GO:0018108///peptidyl-tyrosine phosphorylation","calcium/calmodulin dependent protein kinase kinase 2","[KKCC2_HUMAN|Reviewed]RecName: Full=Calcium/calmodulin-dependent protein kinase kinase 2; Short=CaM-KK 2; Short=CaM-kinase kinase 2; Short=CaMKK 2; EC=2.7.11.17; AltName: Full=Calcium/calmodulin-dependent protein kinase kinase beta; Short=CaM-KK beta; Short=CaM-kinase kinase beta; Short=CaMKK beta;+++[A0A024RBP6_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_b {ECO:0000313|EMBL:EAW98251.1};+++[A0A024RBP8_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_d {ECO:0000313|EMBL:EAW98256.1};+++[A0A024RBQ0_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_f {ECO:0000313|EMBL:EAW98258.1};+++[A0A024RBQ3_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_e {ECO:0000313|EMBL:EAW98257.1};+++[F5GZ00_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000441352};+++[F5H360_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000445400}; Flags: Fragment;+++[F5H4I7_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000444894}; Flags: Fragment;+++[Q8IZW1_HUMAN|Unreviewed]SubName: Full=CAMKK beta protein {ECO:0000313|EMBL:AAN37388.1}; Flags: Fragment;"]
[10647,"'SCGB1D2'",2,5,6,4.33333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space",null,null,"secretoglobin family 1D member 2","[SG1D2_HUMAN|Reviewed]RecName: Full=Secretoglobin family 1D member 2; AltName: Full=Lipophilin-B; Flags: Precursor;"]
[10650,"'PRELID3A'",68,64,62,64.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0005515///protein binding+++GO:1990050///phosphatidic acid transporter activity","GO:0015914///phospholipid transport+++GO:0006869///lipid transport","PRELI domain containing 3A","[PLD3A_HUMAN|Reviewed]RecName: Full=PRELI domain containing protein 3A; AltName: Full=Protein slowmo homolog 1;+++[K7ELB4_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000465996}; Flags: Fragment;+++[K7ENN4_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467026};+++[K7EP78_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467261};+++[K7EPM9_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467457}; Flags: Fragment;+++[K7EQM5_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467896}; Flags: Fragment;"]
[10651,"'MTX2'",169,153,162,161.333333333333,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006839///mitochondrial transport+++GO:0015031///protein transport","metaxin 2","[MTX2_HUMAN|Reviewed]RecName: Full=Metaxin-2; AltName: Full=Mitochondrial outer membrane import complex protein 2;+++[C9JAZ1_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000398757}; Flags: Fragment;+++[C9JNK6_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000414176};+++[F8WCW1_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000403545};+++[F8WE26_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000402204};"]
[10652,"'YKT6'",1681,1569,1571,1607,"04138///Autophagy - yeast+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0097440///apical dendrite+++GO:0005783///endoplasmic reticulum+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0031201///SNARE complex+++GO:0005829///cytosol+++GO:0030133///transport vesicle+++GO:0005739///mitochondrion+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0097441///basal dendrite+++GO:0000139///Golgi membrane+++GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane","GO:0005484///SNAP receptor activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0061025///membrane fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0015031///protein transport+++GO:0006903///vesicle targeting+++GO:0016192///vesicle-mediated transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006888///ER to Golgi vesicle-mediated transport","YKT6 v-SNARE homolog","[YKT6_HUMAN|Reviewed]RecName: Full=Synaptobrevin homolog YKT6; EC=2.3.1.- {ECO:0000269|PubMed:15479160}; Flags: Precursor;+++[A4D2J0_HUMAN|Unreviewed]SubName: Full=SNARE protein Ykt6 {ECO:0000313|EMBL:EAL23763.1}; SubName: Full=SNARE protein Ykt6, isoform CRA_a {ECO:0000313|EMBL:EAW61111.1}; SubName: Full=cDNA, FLJ93006, Homo sapiens SNARE protein Ykt6 (YKT6), mRNA {ECO:0000313|EMBL:BAG35508.1};+++[B5BU81_HUMAN|Unreviewed]SubName: Full=YKT6 v-SNARE protein {ECO:0000313|EMBL:BAG70131.1};+++[H7C3K7_HUMAN|Unreviewed]SubName: Full=Synaptobrevin homolog YKT6 {ECO:0000313|Ensembl:ENSP00000412414}; Flags: Fragment;"]
[10653,"'SPINT2'",1919,1769,1899,1862.33333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane","GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:2000146///negative regulation of cell motility+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010466///negative regulation of peptidase activity+++GO:0060672///epithelial cell morphogenesis involved in placental branching+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0071711///basement membrane organization+++GO:0071773///cellular response to BMP stimulus+++GO:0007163///establishment or maintenance of cell polarity+++GO:0001843///neural tube closure","serine peptidase inhibitor, Kunitz type 2","[SPIT2_HUMAN|Reviewed]RecName: Full=Kunitz-type protease inhibitor 2; AltName: Full=Hepatocyte growth factor activator inhibitor type 2; Short=HAI-2; AltName: Full=Placental bikunin; Flags: Precursor;+++[A0A140VJV6_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 183 {ECO:0000313|EMBL:AEE61093.1};+++[K7EJS4_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465301}; Flags: Fragment;+++[K7EKC8_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465561}; Flags: Fragment;+++[K7EKQ0_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465721}; Flags: Fragment;+++[K7EM91_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000466407};+++[K7ES27_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000468519}; Flags: Fragment;+++[K7ESI5_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000468728}; Flags: Fragment;+++[Q6LEU8_HUMAN|Unreviewed]SubName: Full=SPINT2 protein {ECO:0000313|EMBL:CAG28532.1}; Flags: Fragment;"]
[10675,"'CSPG5'",2755,4070,3447,3424,{"$nulls":4},"GO:0030660///Golgi-associated vesicle membrane+++GO:0099055///integral component of postsynaptic membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005796///Golgi lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0043202///lysosomal lumen+++GO:0098982///GABA-ergic synapse+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0008083///growth factor activity","GO:0040008///regulation of growth+++GO:0046907///intracellular transport+++GO:0030154///cell differentiation+++GO:0030207///chondroitin sulfate catabolic process+++GO:0099550///trans-synaptic signaling, modulating synaptic transmission+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0007399///nervous system development+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0010469///regulation of signaling receptor activity+++GO:2000300///regulation of synaptic vesicle exocytosis","chondroitin sulfate proteoglycan 5","[CSPG5_HUMAN|Reviewed]RecName: Full=Chondroitin sulfate proteoglycan 5; AltName: Full=Acidic leucine-rich EGF-like domain-containing brain protein; AltName: Full=Neuroglycan C; Flags: Precursor;+++[A0A087WUT8_HUMAN|Unreviewed]SubName: Full=Chondroitin sulfate proteoglycan 5 {ECO:0000313|Ensembl:ENSP00000478923};+++[B7Z2E0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54649, highly similar to Chondroitin sulfate proteoglycan 5 {ECO:0000313|EMBL:BAH11826.1};"]
[10718,"'NRG3'",218,246,271,245,"04012///ErbB signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008083///growth factor activity+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0005102///signaling receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0045499///chemorepellent activity","GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0021842///chemorepulsion involved in interneuron migration from the subpallium to the cortex+++GO:0030879///mammary gland development+++GO:0001558///regulation of cell growth+++GO:2001223///negative regulation of neuron migration+++GO:0060596///mammary placode formation+++GO:0035556///intracellular signal transduction+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0010469///regulation of signaling receptor activity+++GO:0050804///modulation of chemical synaptic transmission","neuregulin 3","[NRG3_HUMAN|Reviewed]RecName: Full=Pro-neuregulin-3, membrane-bound isoform; Short=Pro-NRG3; Contains: RecName: Full=Neuregulin-3; Short=NRG-3; Flags: Precursor;+++[B3KVG8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16534 fis, clone OCBBF2029471, highly similar to Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|EMBL:BAG53780.1};+++[B9EGV5_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 {ECO:0000313|EMBL:AAI36812.1};+++[D9ZHP6_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 1 {ECO:0000313|EMBL:ADK90020.1};+++[D9ZHP7_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 3 {ECO:0000313|EMBL:ADK90021.1};+++[D9ZHP8_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 4 {ECO:0000313|EMBL:ADK90022.1};+++[D9ZHP9_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 5 {ECO:0000313|EMBL:ADK90023.1};+++[D9ZHQ0_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 6 {ECO:0000313|EMBL:ADK90024.1};+++[D9ZHQ1_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 7 {ECO:0000313|EMBL:ADK90025.1};+++[D9ZHQ2_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 8 {ECO:0000313|EMBL:ADK90026.1};+++[D9ZHQ3_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 10 {ECO:0000313|EMBL:ADK90028.1}; SubName: Full=Neuregulin 3 variant 9 {ECO:0000313|EMBL:ADK90027.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000451858};+++[D9ZHQ5_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 11 {ECO:0000313|EMBL:ADK90029.1};+++[D9ZHQ6_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 12 {ECO:0000313|EMBL:ADK90030.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000385804};+++[D9ZHQ7_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 13 {ECO:0000313|EMBL:ADK90031.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000451376};+++[D9ZHQ8_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 14 {ECO:0000313|EMBL:ADK90032.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000440377};+++[R4GNI6_HUMAN|Unreviewed]SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000473669};"]
[10728,"'PTGES3'",1624,1400,1577,1533.66666666667,"01100///Metabolic pathways+++00590///Arachidonic acid metabolism",null,null,"R02265///(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase   Prostaglandin H2 <=> Prostaglandin E2","GO:0005697///telomerase holoenzyme complex+++GO:0101031///chaperone complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm","GO:0051879///Hsp90 protein binding+++GO:0016853///isomerase activity+++GO:0050220///prostaglandin-E synthase activity+++GO:0005515///protein binding+++GO:0003720///telomerase activity+++GO:0051082///unfolded protein binding+++GO:0070182///DNA polymerase binding+++GO:0051087///chaperone binding","GO:0019371///cyclooxygenase pathway+++GO:0006629///lipid metabolic process+++GO:0001516///prostaglandin biosynthetic process+++GO:0006805///xenobiotic metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0050821///protein stabilization+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0007004///telomere maintenance via telomerase+++GO:0000723///telomere maintenance+++GO:1905323///telomerase holoenzyme complex assembly+++GO:0006631///fatty acid metabolic process+++GO:0006457///protein folding+++GO:0006693///prostaglandin metabolic process+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:1900034///regulation of cellular response to heat+++GO:0007165///signal transduction+++GO:0042327///positive regulation of phosphorylation+++GO:0051973///positive regulation of telomerase activity","prostaglandin E synthase 3","[TEBP_HUMAN|Reviewed]RecName: Full=Prostaglandin E synthase 3; EC=5.3.99.3 {ECO:0000269|PubMed:10922363}; AltName: Full=Cytosolic prostaglandin E2 synthase; Short=cPGES; AltName: Full=Hsp90 co-chaperone; AltName: Full=Progesterone receptor complex p23; AltName: Full=Telomerase-binding protein p23;+++[A0A024RB32_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 (Cytosolic), isoform CRA_a {ECO:0000313|EMBL:EAW96957.1};+++[A0A087WYT3_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 {ECO:0000313|Ensembl:ENSP00000482075};+++[B3KUY2_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 (Cytosolic), isoform CRA_c {ECO:0000313|EMBL:EAW96955.1}; SubName: Full=cDNA FLJ40895 fis, clone UTERU2002294, highly similar to Prostaglandin E synthase 3 {ECO:0000313|EMBL:BAG53594.1};+++[B4DDC6_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 {ECO:0000313|Ensembl:ENSP00000389090}; SubName: Full=cDNA FLJ59832, moderately similar to Prostaglandin E synthase 3 {ECO:0000313|EMBL:BAG56687.1};"]
[10766,"'TOB2'",1085,1091,1120,1098.66666666667,"03018///RNA degradation",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0042809///vitamin D receptor binding","GO:0008285///negative regulation of cell proliferation+++GO:0045778///positive regulation of ossification+++GO:0007292///female gamete generation+++GO:0010468///regulation of gene expression+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045671///negative regulation of osteoclast differentiation","transducer of ERBB2, 2","[TOB2_HUMAN|Reviewed]RecName: Full=Protein Tob2; AltName: Full=Protein Tob4; AltName: Full=Transducer of erbB-2 2;+++[B0QXZ4_HUMAN|Unreviewed]SubName: Full=Protein Tob2 {ECO:0000313|Ensembl:ENSP00000388549}; Flags: Fragment;"]
[10772,"'SRSF10'",698,642,609,649.666666666667,"03040///Spliceosome",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0050733///RS domain binding+++GO:0003676///nucleic acid binding+++GO:0051082///unfolded protein binding","GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000395///mRNA 5'-splice site recognition+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0016482///cytosolic transport+++GO:0043484///regulation of RNA splicing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0006376///mRNA splice site selection","serine and arginine rich splicing factor 10","[SRS10_HUMAN|Reviewed]RecName: Full=Serine/arginine-rich splicing factor 10; AltName: Full=40 kDa SR-repressor protein; Short=SRrp40; AltName: Full=FUS-interacting serine-arginine-rich protein 1; AltName: Full=Splicing factor SRp38; AltName: Full=Splicing factor, arginine/serine-rich 13A; AltName: Full=TLS-associated protein with Ser-Arg repeats; Short=TASR; Short=TLS-associated protein with SR repeats; AltName: Full=TLS-associated serine-arginine protein; Short=TLS-associated SR protein;+++[A0A0S2Z504_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich splicing factor 10 isoform 1 {ECO:0000313|EMBL:ALQ33994.1}; Flags: Fragment;+++[B3KNY6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30749 fis, clone FEBRA2000402, highly similar to FUS-interacting serine-arginine-rich protein 1 {ECO:0000313|EMBL:BAG51498.1}; SubName: Full=cDNA FLJ43846 fis, clone TESTI4006393, highly similar to FUS-interacting serine-arginine-rich protein 1 {ECO:0000313|EMBL:BAG54253.1};+++[Q5JRI1_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 10 {ECO:0000313|Ensembl:ENSP00000363577};+++[Q6IQ42_HUMAN|Unreviewed]SubName: Full=FUSIP1 protein {ECO:0000313|EMBL:AAH71575.1}; SubName: Full=Serine/arginine-rich-splicing factor 10 {ECO:0000313|Ensembl:ENSP00000473291};+++[R4GMP8_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich splicing factor 10 isoform 2 {ECO:0000313|EMBL:ALQ33995.1}; SubName: Full=Serine/arginine-rich-splicing factor 10 {ECO:0000313|Ensembl:ENSP00000473293};"]
[10797,"'MTHFD2'",164,158,157,159.666666666667,"00670///One carbon pool by folate+++01100///Metabolic pathways",null,"M00141///C1-unit interconversion, eukaryotes","R01655///5,10-Methenyltetrahydrofolate 5-hydrolase (decyclizing)   5,10-Methenyltetrahydrofolate + H2O <=> 10-Formyltetrahydrofolate + H++++R01218///5,10-methylenetetrahydrofolate:NAD+ oxidoreductase   5,10-Methylenetetrahydrofolate + NAD+ <=> 5,10-Methenyltetrahydrofolate + NADH","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005615///extracellular space","GO:0042301///phosphate ion binding+++GO:0016491///oxidoreductase activity+++GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0003824///catalytic activity+++GO:0004487///methylenetetrahydrofolate dehydrogenase (NAD+) activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity","GO:0006730///one-carbon metabolic process+++GO:0008152///metabolic process+++GO:0046655///folic acid metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0055114///oxidation-reduction process","methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase","[MTDC_HUMAN|Reviewed]RecName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Includes: RecName: Full=NAD-dependent methylenetetrahydrofolate dehydrogenase {ECO:0000303|PubMed:16100107}; EC=1.5.1.15; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Flags: Precursor;+++[B8ZZU9_HUMAN|Unreviewed]SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000386542};+++[B9A062_HUMAN|Unreviewed]SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000386536};+++[F8WF06_HUMAN|Unreviewed]SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000419550};+++[F8WF89_HUMAN|Unreviewed]SubName: Full=Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000419067};"]
[107984125,"'LOC107984125'",2,0,1,1,{"$nulls":4},"GO:0005930///axoneme+++GO:0032391///photoreceptor connecting cilium+++GO:0097542///ciliary tip+++GO:0001917///photoreceptor inner segment+++GO:0005874///microtubule+++GO:0001750///photoreceptor outer segment+++GO:0005875///microtubule associated complex","GO:0008017///microtubule binding","GO:0045494///photoreceptor cell maintenance+++GO:0035845///photoreceptor cell outer segment organization+++GO:0035556///intracellular signal transduction+++GO:0042461///photoreceptor cell development+++GO:0046549///retinal cone cell development+++GO:0046548///retinal rod cell development+++GO:0007601///visual perception+++GO:0060041///retina development in camera-type eye+++GO:0007603///phototransduction, visible light+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:0035082///axoneme assembly+++GO:0071482///cellular response to light stimulus","lipoxygenase homology domain-containing protein 1-like","[LOXH1_HUMAN|diamond]RecName: Full=Lipoxygenase homology domain-containing protein 1;+++[LOXH1_MOUSE|diamond]RecName: Full=Lipoxygenase homology domain-containing protein 1;+++[PK1L_ACRMI|diamond]RecName: Full=Polycystic kidney disease 1-related protein {ECO:0000303|PubMed:23765379}; Flags: Precursor; Fragment;+++[PKD1_HUMAN|diamond]RecName: Full=Polycystin-1; Short=PC1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein; Flags: Precursor;+++[PKD1_MOUSE|diamond]RecName: Full=Polycystin-1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein homolog; Flags: Precursor;+++[RP1_BOVIN|diamond]RecName: Full=Oxygen-regulated protein 1; AltName: Full=Retinitis pigmentosa RP1 protein homolog;+++[RP1_HUMAN|diamond]RecName: Full=Oxygen-regulated protein 1; AltName: Full=Retinitis pigmentosa 1 protein; AltName: Full=Retinitis pigmentosa RP1 protein;+++[RP1_MOUSE|diamond]RecName: Full=Oxygen-regulated protein 1; AltName: Full=Retinitis pigmentosa RP1 protein homolog;+++[RP1_PAPHA|diamond]RecName: Full=Oxygen-regulated protein 1; AltName: Full=Retinitis pigmentosa RP1 protein homolog;+++[RP1_SAIBB|diamond]RecName: Full=Oxygen-regulated protein 1; AltName: Full=Retinitis pigmentosa RP1 protein homolog;"]
[107984751,"'LOC107984751'",1,2.07,2.8,1.95666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0004197///cysteine-type endopeptidase activity","GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process","uncharacterized LOC107984751","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[107985115,"'LOC107985115'",8,12,15,11.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043621///protein self-association+++GO:0046872///metal ion binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated","translation initiation factor IF-2-like","[BEND2_HUMAN|diamond]RecName: Full=BEN domain-containing protein 2;+++[CCNJL_HUMAN|diamond]RecName: Full=Cyclin-J-like protein;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZKSC3_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 3; AltName: Full=Zinc finger and SCAN domain-containing protein 13; AltName: Full=Zinc finger protein 306; AltName: Full=Zinc finger protein 309; AltName: Full=Zinc finger protein 47 homolog; Short=Zf47; Short=Zfp-47;+++[ZKSC4_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 4; AltName: Full=P373c6.1; AltName: Full=Zinc finger protein 307; AltName: Full=Zinc finger protein 427;+++[ZN202_HUMAN|diamond]RecName: Full=Zinc finger protein 202; AltName: Full=Zinc finger protein with KRAB and SCAN domains 10;+++[ZN496_HUMAN|diamond]RecName: Full=Zinc finger protein 496; AltName: Full=Zinc finger protein with KRAB and SCAN domains 17;+++[ZN496_MOUSE|diamond]RecName: Full=Zinc finger protein 496; AltName: Full=NSD1-interacting zinc finger protein 1; AltName: Full=Zinc finger protein with KRAB and SCAN domains 17;"]
[107985856,"'LOC107985856'",2.18,0,0,0.726666666666667,{"$nulls":7},"uncharacterized LOC107985856","[G7N9H1_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH21918.1}; Flags: Fragment;+++[G7PLP6_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH55391.1}; Flags: Fragment;"]
[107986531,"'LOC107986531'",0,3,0,1,{"$nulls":7},"translation initiation factor IF-2-like"]
[107986810,"'LOC107986810'",3,2.42,5.97,3.79666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"uncharacterized LOC107986810","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[107987290,"'LOC107987290'",2.61,2.33,3,2.64666666666667,{"$nulls":7},"uncharacterized LOC107987290","[A0A2I3S0H5_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000070489};+++[A0A2I3S5Y0_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000072439};+++[A0A2I3T7N2_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000084888};+++[H2PUM8_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000022415};+++[Q69YS9_HUMAN|diamond]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[10799,"'RPP40'",48,35,34,39,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005655///nucleolar ribonuclease P complex","GO:0016787///hydrolase activity+++GO:0004526///ribonuclease P activity","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0008033///tRNA processing+++GO:0090501///RNA phosphodiester bond hydrolysis","ribonuclease P/MRP subunit p40","[RPP40_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p40; Short=RNaseP protein p40; EC=3.1.26.5; AltName: Full=RNase P subunit 1;+++[A0A087X1N3_HUMAN|Unreviewed]SubName: Full=Ribonuclease P 40kDa subunit, isoform CRA_c {ECO:0000313|EMBL:EAW55172.1}; SubName: Full=Ribonuclease P protein subunit p40 {ECO:0000313|Ensembl:ENSP00000484334};+++[F8WC38_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p40 {ECO:0000313|Ensembl:ENSP00000418874};+++[L8E9F2_HUMAN|Unreviewed]SubName: Full=Alternative protein RPP40 {ECO:0000313|EMBL:CCQ43366.1};+++[X6RLL4_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p40 {ECO:0000313|Ensembl:ENSP00000419431};"]
[10817,"'FRS3'",138,183,163,161.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005104///fibroblast growth factor receptor binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0000165///MAPK cascade+++GO:0007165///signal transduction","fibroblast growth factor receptor substrate 3","[FRS3_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor receptor substrate 3; Short=FGFR substrate 3; AltName: Full=FGFR-signaling adaptor SNT2; AltName: Full=Suc1-associated neurotrophic factor target 2; Short=SNT-2;+++[A0A0A0MSM8_HUMAN|Unreviewed]SubName: Full=Fibroblast growth factor receptor substrate 3 {ECO:0000313|Ensembl:ENSP00000396715}; Flags: Fragment;+++[A0A140VJJ7_HUMAN|Unreviewed]SubName: Full=Fibroblast growth factor receptor substrate 3 {ECO:0000313|EMBL:EAX04060.1}; SubName: Full=Testicular tissue protein Li 71 {ECO:0000313|EMBL:AEE60984.1};+++[A6PVU0_HUMAN|Unreviewed]SubName: Full=Fibroblast growth factor receptor substrate 3 {ECO:0000313|Ensembl:ENSP00000413214}; Flags: Fragment;"]
[10856,"'RUVBL2'",1099,1168,1106,1124.33333333333,{"$nulls":4},"GO:0000812///Swr1 complex+++GO:1990904///ribonucleoprotein complex+++GO:0016363///nuclear matrix+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005622///intracellular+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0005719///nuclear euchromatin+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0097255///R2TP complex+++GO:0071339///MLL1 complex+++GO:0031011///Ino80 complex+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003678///DNA helicase activity+++GO:0016887///ATPase activity+++GO:0017025///TBP-class protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0031490///chromatin DNA binding+++GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding+++GO:0043141///ATP-dependent 5'-3' DNA helicase activity+++GO:0005524///ATP binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0005515///protein binding+++GO:0043531///ADP binding+++GO:0051082///unfolded protein binding+++GO:0008013///beta-catenin binding+++GO:0051117///ATPase binding+++GO:0004386///helicase activity","GO:0071169///establishment of protein localization to chromatin+++GO:0071899///negative regulation of estrogen receptor binding+++GO:0043968///histone H2A acetylation+++GO:0071392///cellular response to estradiol stimulus+++GO:0006281///DNA repair+++GO:0016573///histone acetylation+++GO:0034644///cellular response to UV+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0006338///chromatin remodeling+++GO:0035066///positive regulation of histone acetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006457///protein folding+++GO:0071733///transcriptional activation by promoter-enhancer looping+++GO:0040008///regulation of growth+++GO:0032508///DNA duplex unwinding+++GO:0006325///chromatin organization+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043967///histone H4 acetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000492///box C/D snoRNP assembly","RuvB like AAA ATPase 2","[RUVB2_HUMAN|Reviewed]RecName: Full=RuvB-like 2; EC=3.6.4.12; AltName: Full=48 kDa TATA box-binding protein-interacting protein; Short=48 kDa TBP-interacting protein; AltName: Full=51 kDa erythrocyte cytosolic protein; Short=ECP-51; AltName: Full=INO80 complex subunit J; AltName: Full=Repressing pontin 52; Short=Reptin 52; AltName: Full=TIP49b; AltName: Full=TIP60-associated protein 54-beta; Short=TAP54-beta;+++[A0A1W2PS22_HUMAN|Unreviewed]SubName: Full=RuvB-like 2 {ECO:0000313|Ensembl:ENSP00000492564};+++[A0A1W2PS48_HUMAN|Unreviewed]RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048}; EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048};+++[B3KNL2_HUMAN|Unreviewed]RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048}; EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048};+++[M0QXI6_HUMAN|Unreviewed]RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048}; EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048}; Flags: Fragment;+++[M0QXZ7_HUMAN|Unreviewed]SubName: Full=RuvB-like 2 (E. coli), isoform CRA_b {ECO:0000313|EMBL:EAW52427.1};+++[M0QYD8_HUMAN|Unreviewed]SubName: Full=RuvB-like 2 (E. coli), isoform CRA_c {ECO:0000313|EMBL:EAW52428.1};+++[M0R0Y3_HUMAN|Unreviewed]RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048}; EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048};+++[M0R0Z0_HUMAN|Unreviewed]RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048}; EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048};+++[X6R2L4_HUMAN|Unreviewed]RecName: Full=RuvB-like helicase {ECO:0000256|RuleBase:RU363048}; EC=3.6.4.12 {ECO:0000256|RuleBase:RU363048};"]
[10882,"'C1QL1'",452,449,372,424.333333333333,{"$nulls":4},"GO:0098793///presynapse+++GO:0043083///synaptic cleft+++GO:0044301///climbing fiber+++GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005581///collagen trimer+++GO:0005576///extracellular region","GO:0003674///molecular_function+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding","GO:0007626///locomotory behavior+++GO:0061743///motor learning+++GO:0016322///neuron remodeling+++GO:0099558///maintenance of synapse structure","complement C1q like 1","[C1QRF_HUMAN|Reviewed]RecName: Full=C1q-related factor; AltName: Full=C1q and tumor necrosis factor-related protein 14; Short=C1q/TNF-related protein 14; AltName: Full=Complement component 1 Q subcomponent-like 1; Flags: Precursor;"]
[10899,"'JTB'",1684,1362,1433,1493,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005813///centrosome","GO:0019901///protein kinase binding","GO:0051301///cell division+++GO:0000281///mitotic cytokinesis+++GO:0006915///apoptotic process+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0045860///positive regulation of protein kinase activity","jumping translocation breakpoint","[JTB_HUMAN|Reviewed]RecName: Full=Protein JTB; AltName: Full=Jumping translocation breakpoint protein; AltName: Full=Prostate androgen-regulated protein; Short=PAR protein; Flags: Precursor;"]
[10922,"'FASTK'",818,867,847,844,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0033867///Fas-activated serine/threonine kinase activity","GO:0006915///apoptotic process+++GO:0097190///apoptotic signaling pathway+++GO:0016310///phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0006468///protein phosphorylation","Fas activated serine/threonine kinase","[FASTK_HUMAN|Reviewed]RecName: Full=Fas-activated serine/threonine kinase; Short=FAST kinase; EC=2.7.11.8;+++[A0A090N8I0_HUMAN|Unreviewed]SubName: Full=FAST kinase {ECO:0000313|EMBL:EAL24499.1};+++[A0A090N8Z7_HUMAN|Unreviewed]SubName: Full=FAST kinase {ECO:0000313|EMBL:EAL24500.1};+++[G3V1R6_HUMAN|Unreviewed]SubName: Full=Fas-activated serine/threonine kinase {ECO:0000313|Ensembl:ENSP00000444498};+++[Q9BWD7_HUMAN|Unreviewed]SubName: Full=FASTK protein {ECO:0000313|EMBL:AAH00377.1};"]
[10939,"'AFG3L2'",895,894,890,893,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00063///Spinocerebellar ataxia (SCA)+++H01351///Spastic ataxia (SPAX)",null,null,"GO:0005743///mitochondrial inner membrane+++GO:0005745///m-AAA complex+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity","GO:0016485///protein processing+++GO:0021675///nerve development+++GO:0048747///muscle fiber development+++GO:0040014///regulation of multicellular organism growth+++GO:0007409///axonogenesis+++GO:0042552///myelination+++GO:0042407///cristae formation+++GO:0034982///mitochondrial protein processing+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0016540///protein autoprocessing+++GO:0036444///calcium import into the mitochondrion+++GO:0007528///neuromuscular junction development+++GO:0006508///proteolysis+++GO:0008053///mitochondrial fusion+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0007005///mitochondrion organization+++GO:0060013///righting reflex","AFG3 like matrix AAA peptidase subunit 2","[AFG32_HUMAN|Reviewed]RecName: Full=AFG3-like protein 2; EC=3.4.24.- {ECO:0000269|PubMed:14623864}; AltName: Full=Paraplegin-like protein; Flags: Precursor;+++[D3DUJ0_HUMAN|Unreviewed]SubName: Full=AFG3 ATPase family gene 3-like 2 (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAX01552.1}; Flags: Fragment;+++[K7EP56_HUMAN|Unreviewed]SubName: Full=AFG3-like protein 2 {ECO:0000313|Ensembl:ENSP00000467236}; Flags: Fragment;+++[Q8TA92_HUMAN|Unreviewed]SubName: Full=Similar to AFG3 ATPase family gene 3-like 2 (Yeast) {ECO:0000313|EMBL:AAH24282.1}; Flags: Fragment;"]
[10955,"'SERINC3'",742.09,563,623,642.696666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0015194///L-serine transmembrane transporter activity","GO:0006658///phosphatidylserine metabolic process+++GO:0015825///L-serine transport+++GO:0006564///L-serine biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0045087///innate immune response+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0002376///immune system process+++GO:0009597///detection of virus+++GO:0051607///defense response to virus","serine incorporator 3","[SERC3_HUMAN|Reviewed]RecName: Full=Serine incorporator 3; AltName: Full=Tumor differentially expressed protein 1 {ECO:0000303|PubMed:10559794};+++[L8E9G1_HUMAN|Unreviewed]SubName: Full=Alternative protein SERINC3 {ECO:0000313|EMBL:CCQ43376.1};+++[L8ECD5_HUMAN|Unreviewed]SubName: Full=Alternative protein SERINC3 {ECO:0000313|EMBL:CCQ43377.1};+++[Q5H936_HUMAN|Unreviewed]SubName: Full=Serine incorporator 3 {ECO:0000313|Ensembl:ENSP00000414197}; Flags: Fragment;"]
[10981,"'RAB32'",551,492,500,514.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005802///trans-Golgi network+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0042470///melanosome+++GO:0031905///early endosome lumen+++GO:0033162///melanosome membrane+++GO:0005739///mitochondrion+++GO:0031982///vesicle+++GO:0005783///endoplasmic reticulum+++GO:0031410///cytoplasmic vesicle+++GO:0045335///phagocytic vesicle+++GO:0030670///phagocytic vesicle membrane+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005741///mitochondrial outer membrane","GO:0035650///AP-1 adaptor complex binding+++GO:0036461///BLOC-2 complex binding+++GO:0030742///GTP-dependent protein binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding+++GO:0035651///AP-3 adaptor complex binding+++GO:0005525///GTP binding+++GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0035646///endosome to melanosome transport+++GO:0072657///protein localization to membrane+++GO:0090382///phagosome maturation+++GO:0032482///Rab protein signal transduction+++GO:0007005///mitochondrion organization+++GO:0019882///antigen processing and presentation+++GO:1903232///melanosome assembly+++GO:0016192///vesicle-mediated transport","RAB32, member RAS oncogene family","[RAB32_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-32;"]
[10998,"'SLC27A5'",26,24,27,25.6666666666667,"04976///Bile secretion+++04931///Insulin resistance+++03320///PPAR signaling pathway+++01100///Metabolic pathways+++00120///Primary bile acid biosynthesis",null,"M00106///Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate+++M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R04580///3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)   ATP + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + CoA <=> AMP + Diphosphate + 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA+++R02794///Cholate:CoA ligase (AMP-forming)   ATP + Cholic acid + CoA <=> AMP + Diphosphate + Choloyl-CoA+++R08733///3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate:CoA ligase (AMP-forming)   3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate + ATP + CoA <=> (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + Diphosphate+++R08738///3alpha,7alpha-dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)   3alpha,7alpha-Dihydroxy-5beta-cholestanate + ATP + CoA <=> (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + AMP + Diphosphate+++R04507///3alpha,7alpha-Dihydroxy-5beta-cholestanate:CoA ligase (AMP-forming)   ATP + 3alpha,7alpha-Dihydroxy-5beta-cholestanate + CoA <=> AMP + Diphosphate + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R08743///chenodeoxycholate:CoA ligase (AMP-forming)   Chenodeoxycholoyl-CoA + AMP + Diphosphate <=> Chenodeoxycholate + CoA + ATP","GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0009925///basal plasma membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0044877///protein-containing complex binding+++GO:0015245///fatty acid transmembrane transporter activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0047747///cholate-CoA ligase activity+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0000166///nucleotide binding+++GO:0005324///long-chain fatty acid transporter activity+++GO:0003824///catalytic activity","GO:0015721///bile acid and bile salt transport+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0008206///bile acid metabolic process+++GO:0015908///fatty acid transport+++GO:0000038///very long-chain fatty acid metabolic process+++GO:0006642///triglyceride mobilization+++GO:0015911///plasma membrane long-chain fatty acid transport+++GO:0006629///lipid metabolic process+++GO:0046951///ketone body biosynthetic process+++GO:0006699///bile acid biosynthetic process","solute carrier family 27 member 5","[S27A5_HUMAN|Reviewed]RecName: Full=Bile acyl-CoA synthetase; Short=BACS; EC=6.2.1.7; AltName: Full=Bile acid-CoA ligase; Short=BA-CoA ligase; Short=BAL; AltName: Full=Cholate--CoA ligase; AltName: Full=Fatty acid transport protein 5; Short=FATP-5; AltName: Full=Fatty-acid-coenzyme A ligase, very long-chain 3; AltName: Full=Solute carrier family 27 member 5; AltName: Full=Very long-chain acyl-CoA synthetase homolog 2; Short=VLCS-H2; Short=VLCSH2; AltName: Full=Very long-chain acyl-CoA synthetase-related protein; Short=VLACS-related; Short=VLACSR;+++[M0R075_HUMAN|Unreviewed]SubName: Full=Bile acyl-CoA synthetase {ECO:0000313|Ensembl:ENSP00000471065};"]
[110091775,"'C21orf59-TCP10L'",0,0,15.72,5.24,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005856///cytoskeleton","GO:0070491///repressing transcription factor binding+++GO:0003714///transcription corepressor activity+++GO:0043621///protein self-association+++GO:0042802///identical protein binding","GO:0060271///cilium assembly+++GO:0048858///cell projection morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003352///regulation of cilium movement","C21orf59-TCP10L readthrough","[C298A_XENLA|diamond]RecName: Full=Cilia- and flagella-associated protein 298-A {ECO:0000305}; AltName: Full=Protein kurly-A {ECO:0000305};+++[CF298_DANRE|diamond]RecName: Full=Cilia- and flagella-associated protein 298 {ECO:0000305}; AltName: Full=Protein kurly {ECO:0000303|PubMed:26904945};+++[CF298_HUMAN|diamond]RecName: Full=Cilia- and flagella-associated protein 298 {ECO:0000305}; AltName: Full=Protein kurly homolog {ECO:0000305};+++[CF298_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 298 {ECO:0000305}; AltName: Full=Protein kurly homolog {ECO:0000305};+++[CF298_RAT|diamond]RecName: Full=Cilia- and flagella-associated protein 298 {ECO:0000305}; AltName: Full=Protein kurly homolog {ECO:0000305};+++[CU077_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00846;+++[TCP10_HUMAN|diamond]RecName: Full=T-complex protein 10A homolog;+++[TCP1L_HUMAN|diamond]RecName: Full=T-complex protein 10A homolog 1; Short=T-complex protein 10A-1; Short=TCP10A-1; AltName: Full=TCP10-like;+++[TCP1L_PANTR|diamond]RecName: Full=T-complex protein 10A homolog 1; Short=T-complex protein 10A-1; Short=TCP10A-1; AltName: Full=TCP10-like;+++[TCP2L_HUMAN|diamond]RecName: Full=T-complex protein 10A homolog 2; AltName: Full=T-complex 10-like protein 2;"]
[110354863,"'ZNF660-ZNF197'",19.13,59.93,16.14,31.7333333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0005623///cell","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated+++GO:0071300///cellular response to retinoic acid+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis","ZNF660-ZNF197 readthrough","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[ZFP2_HUMAN|diamond]RecName: Full=Zinc finger protein 2 homolog; Short=Zfp-2; AltName: Full=Zinc finger protein 751;+++[ZKSC5_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 5; AltName: Full=Zinc finger protein 95 homolog; Short=Zfp-95;+++[ZKSC7_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 7; AltName: Full=Zinc finger protein 167; AltName: Full=Zinc finger protein 448; AltName: Full=Zinc finger protein 64;+++[ZN135_BOVIN|diamond]RecName: Full=Zinc finger protein 135;+++[ZN135_HUMAN|diamond]RecName: Full=Zinc finger protein 135; AltName: Full=Zinc finger protein 61; AltName: Full=Zinc finger protein 78-like 1;+++[ZN180_HUMAN|diamond]RecName: Full=Zinc finger protein 180; AltName: Full=HHZ168;+++[ZN197_HUMAN|diamond]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[ZN202_HUMAN|diamond]RecName: Full=Zinc finger protein 202; AltName: Full=Zinc finger protein with KRAB and SCAN domains 10;+++[ZN268_HUMAN|diamond]RecName: Full=Zinc finger protein 268; AltName: Full=Zinc finger protein HZF3;+++[ZN345_HUMAN|diamond]RecName: Full=Zinc finger protein 345; AltName: Full=Zinc finger protein HZF10;+++[ZN394_HUMAN|diamond]RecName: Full=Zinc finger protein 394; AltName: Full=Zinc finger protein with KRAB and SCAN domains 14;+++[ZN394_PANPA|diamond]RecName: Full=Zinc finger protein 394;+++[ZN445_HUMAN|diamond]RecName: Full=Zinc finger protein 445; AltName: Full=Zinc finger protein 168; AltName: Full=Zinc finger protein with KRAB and SCAN domains 15;+++[ZN445_MOUSE|diamond]RecName: Full=Zinc finger protein 445;+++[ZN565_HUMAN|diamond]RecName: Full=Zinc finger protein 565;+++[ZN660_HUMAN|diamond]RecName: Full=Zinc finger protein 660;+++[ZN721_HUMAN|diamond]RecName: Full=Zinc finger protein 721;+++[ZN845_HUMAN|diamond]RecName: Full=Zinc finger protein 845;+++[ZN850_HUMAN|diamond]RecName: Full=Zinc finger protein 850;+++[ZN852_HUMAN|diamond]RecName: Full=Zinc finger protein 852;+++[ZNF35_HUMAN|diamond]RecName: Full=Zinc finger protein 35; AltName: Full=Zinc finger protein HF.10;"]
[11055,"'ZPBP'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0031410///cytoplasmic vesicle+++GO:0002080///acrosomal membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region",null,"GO:0007339///binding of sperm to zona pellucida","zona pellucida binding protein","[ZPBP1_HUMAN|Reviewed]RecName: Full=Zona pellucida-binding protein 1; AltName: Full=Inner acrosomal membrane IAM38 {ECO:0000250|UniProtKB:Q62522}; AltName: Full=Sp38; Flags: Precursor;+++[C9JIS7_HUMAN|Unreviewed]SubName: Full=Zona pellucida-binding protein 1 {ECO:0000313|Ensembl:ENSP00000390054}; Flags: Fragment;+++[F8WDW2_HUMAN|Unreviewed]SubName: Full=Zona pellucida-binding protein 1 {ECO:0000313|Ensembl:ENSP00000414755};"]
[11062,"'DUS4L'",59,60,56,58.3333333333333,{"$nulls":4},"GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0017119///Golgi transport complex+++GO:0000139///Golgi membrane","GO:0003824///catalytic activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0017150///tRNA dihydrouridine synthase activity+++GO:0016491///oxidoreductase activity","GO:0008033///tRNA processing+++GO:0002943///tRNA dihydrouridine synthesis+++GO:0055114///oxidation-reduction process","dihydrouridine synthase 4 like","[DUS4L_HUMAN|Reviewed]RecName: Full=tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; EC=1.3.1.-; AltName: Full=pp35; AltName: Full=tRNA-dihydrouridine synthase 4-like;+++[A0A024R6Z3_HUMAN|Unreviewed]SubName: Full=Dihydrouridine synthase 4-like (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW83403.1};+++[A4D0R5_HUMAN|Unreviewed]RecName: Full=tRNA-dihydrouridine synthase {ECO:0000256|PIRNR:PIRNR006621}; EC=1.3.1.- {ECO:0000256|PIRNR:PIRNR006621};+++[F2Z2E4_HUMAN|Unreviewed]SubName: Full=tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like {ECO:0000313|Ensembl:ENSP00000412739};+++[F8WEL2_HUMAN|Unreviewed]SubName: Full=tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like {ECO:0000313|Ensembl:ENSP00000388061};+++[F8WFE3_HUMAN|Unreviewed]SubName: Full=tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like {ECO:0000313|Ensembl:ENSP00000399375};"]
[11093,"'ADAMTS13'",106,118,112,112,null,"H00225///Thrombotic thrombocytopenic purpura (TTP)",null,null,"GO:0031012///extracellular matrix+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0009986///cell surface","GO:0004222///metalloendopeptidase activity+++GO:0008270///zinc ion binding+++GO:0004175///endopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008233///peptidase activity+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0034612///response to tumor necrosis factor+++GO:0071353///cellular response to interleukin-4+++GO:0007599///hemostasis+++GO:0071346///cellular response to interferon-gamma+++GO:0007229///integrin-mediated signaling pathway+++GO:0030168///platelet activation+++GO:0043171///peptide catabolic process+++GO:0016485///protein processing+++GO:0009636///response to toxic substance+++GO:0034341///response to interferon-gamma+++GO:0014075///response to amine+++GO:0035864///response to potassium ion+++GO:0007596///blood coagulation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0070670///response to interleukin-4+++GO:0006508///proteolysis+++GO:0007160///cell-matrix adhesion+++GO:0009100///glycoprotein metabolic process+++GO:0071356///cellular response to tumor necrosis factor","ADAM metallopeptidase with thrombospondin type 1 motif 13","[ATS13_HUMAN|Reviewed]RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 13; Short=ADAM-TS 13; Short=ADAM-TS13; Short=ADAMTS-13; EC=3.4.24.87 {ECO:0000269|PubMed:11535495}; AltName: Full=von Willebrand factor-cleaving protease; Short=vWF-CP; Short=vWF-cleaving protease; Flags: Precursor;+++[A0A024R8G4_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase with thrombospondin type 1 motif, 13, isoform CRA_a {ECO:0000313|EMBL:EAW88084.1};+++[A0A0B4J229_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 13 {ECO:0000313|Ensembl:ENSP00000435274};+++[A0A0C4DFV8_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 13 {ECO:0000313|Ensembl:ENSP00000360978};+++[A0A2D0ZBS7_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase with thrombospondin type 1 motif 13 {ECO:0000313|EMBL:ASW23237.1}; Flags: Fragment;+++[D5KRM8_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase with thrombospondin type 1 motif 13 {ECO:0000313|EMBL:ADD92168.1}; EC=3.4.24.- {ECO:0000313|EMBL:ADD92168.1}; Flags: Fragment;+++[E7EV88_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 13 {ECO:0000313|Ensembl:ENSP00000360984};+++[F6V803_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 13 {ECO:0000313|Ensembl:ENSP00000435305};+++[Q6QNA4_HUMAN|Unreviewed]SubName: Full=von Willebrand factor-cleaving protease {ECO:0000313|EMBL:AAS54904.1}; Flags: Fragment;+++[Q6QNA5_HUMAN|Unreviewed]SubName: Full=von Willebrand factor-cleaving protease {ECO:0000313|EMBL:AAS54903.1}; Flags: Fragment;+++[Q6QNA6_HUMAN|Unreviewed]SubName: Full=von Willebrand factor-cleaving protease {ECO:0000313|EMBL:AAS54902.1}; Flags: Fragment;+++[Q6QNA7_HUMAN|Unreviewed]SubName: Full=von Willebrand factor-cleaving protease {ECO:0000313|EMBL:AAS54901.1}; Flags: Fragment;+++[Q96P40_HUMAN|Unreviewed]SubName: Full=ADAMTS13 {ECO:0000313|EMBL:AAL11094.1}; Flags: Fragment;"]
[11102,"'RPP14'",228.7,105.58,157.61,163.963333333333,"03013///RNA transport",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0030681///multimeric ribonuclease P complex+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0016787///hydrolase activity+++GO:0004540///ribonuclease activity+++GO:0004526///ribonuclease P activity+++GO:0003723///RNA binding","GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing","ribonuclease P/MRP subunit p14","[RPP14_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p14; EC=3.1.26.5;"]
[11129,"'CLASRP'",474,617,538,543,"04064///NF-kappa B signaling pathway+++05169///Epstein-Barr virus infection+++04137///Mitophagy - animal+++04010///MAPK signaling pathway+++04380///Osteoclast differentiation+++05166///HTLV-I infection+++04140///Autophagy - animal+++04625///C-type lectin receptor signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing","CLK4 associating serine/arginine rich protein","[CLASR_HUMAN|Reviewed]RecName: Full=CLK4-associating serine/arginine rich protein; AltName: Full=Splicing factor, arginine/serine-rich 16; AltName: Full=Suppressor of white-apricot homolog 2;+++[A0A0A0MQS2_HUMAN|Unreviewed]SubName: Full=CLK4-associating serine/arginine-rich protein {ECO:0000313|Ensembl:ENSP00000221455}; SubName: Full=Splicing factor, arginine/serine-rich 16 (Suppressor-of-white-apricot homolog, Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW57317.1};+++[F5H0Q6_HUMAN|Unreviewed]SubName: Full=CLK4-associating serine/arginine-rich protein {ECO:0000313|Ensembl:ENSP00000438702}; SubName: Full=Splicing factor, arginine/serine-rich 16 (Suppressor-of-white-apricot homolog, Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW57318.1};+++[K7EKC9_HUMAN|Unreviewed]SubName: Full=CLK4-associating serine/arginine-rich protein {ECO:0000313|Ensembl:ENSP00000465562}; Flags: Fragment;+++[K7EKR8_HUMAN|Unreviewed]SubName: Full=CLK4-associating serine/arginine-rich protein {ECO:0000313|Ensembl:ENSP00000465750};+++[K7EM61_HUMAN|Unreviewed]SubName: Full=CLK4-associating serine/arginine-rich protein {ECO:0000313|Ensembl:ENSP00000466371}; Flags: Fragment;+++[K7EP11_HUMAN|Unreviewed]SubName: Full=CLK4-associating serine/arginine-rich protein {ECO:0000313|Ensembl:ENSP00000467177}; Flags: Fragment;"]
[11145,"'PLA2G16'",1486.87,1535,1275.05,1432.30666666667,"00591///Linoleic acid metabolism+++04923///Regulation of lipolysis in adipocytes+++01100///Metabolic pathways+++00564///Glycerophospholipid metabolism+++00590///Arachidonic acid metabolism+++04014///Ras signaling pathway+++01110///Biosynthesis of secondary metabolites+++00565///Ether lipid metabolism+++00592///alpha-Linolenic acid metabolism",null,null,"R07859///Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid+++R01315///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid+++R02053///phosphatidylethanolamine 2-acylhydrolase   Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid+++R07064///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate+++R01316///phosphatidylcholine 1-acylhydrolase   Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + Fatty acid+++R04034///phosphatidylserine 1-acylhydrolase   Phosphatidylserine + H2O <=> 2-Acyl-sn-glycero-3-phosphoserine + Fatty acid+++R07387///plasmanylcholine 2-acylhydrolase   1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate+++R02054///phosphatidylethanolamine 1-acylhydrolase   Phosphatidylethanolamine + H2O <=> 2-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid+++R07860///Phosphatidylcholine + H2O <=> 2-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid+++R01317///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate+++R07379///plasmenylethanolamine 2-acylhydrolase   O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate","GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0005575///cellular_component+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane","GO:0008970///phospholipase A1 activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0005515///protein binding+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity+++GO:0016787///hydrolase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0004623///phospholipase A2 activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity","GO:0046485///ether lipid metabolic process+++GO:1904177///regulation of adipose tissue development+++GO:0006641///triglyceride metabolic process+++GO:0045786///negative regulation of cell cycle+++GO:0006629///lipid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0036149///phosphatidylinositol acyl-chain remodeling+++GO:0016042///lipid catabolic process+++GO:0009617///response to bacterium+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0007031///peroxisome organization","phospholipase A2 group XVI","[PA216_HUMAN|Reviewed]RecName: Full=HRAS-like suppressor 3 {ECO:0000303|PubMed:17374643}; Short=HRSL3 {ECO:0000303|PubMed:17374643}; EC=3.1.1.32 {ECO:0000269|PubMed:19047760, ECO:0000269|PubMed:19615464, ECO:0000269|PubMed:20837014, ECO:0000269|PubMed:22605381, ECO:0000269|PubMed:22923616}; EC=3.1.1.4 {ECO:0000269|PubMed:19047760, ECO:0000269|PubMed:19615464, ECO:0000269|PubMed:20837014, ECO:0000269|PubMed:22605381, ECO:0000269|PubMed:22923616}; AltName: Full=Adipose-specific phospholipase A2 {ECO:0000250|UniProtKB:Q8R3U1}; Short=AdPLA {ECO:0000250|UniProtKB:Q8R3U1}; AltName: Full=Group XVI phospholipase A1/A2 {ECO:0000312|HGNC:HGNC:17825}; AltName: Full=H-rev 107 protein homolog {ECO:0000303|PubMed:9771974}; Short=H-REV107 {ECO:0000303|PubMed:9771974}; Short=HREV107-1 {ECO:0000303|PubMed:9771974}; AltName: Full=HRAS-like suppressor 1; AltName: Full=HREV107-3; AltName: Full=Renal carcinoma antigen NY-REN-65 {ECO:0000303|PubMed:10508479};+++[A0A024R561_HUMAN|Unreviewed]SubName: Full=HRAS-like suppressor 3, isoform CRA_a {ECO:0000313|EMBL:EAW74160.1};+++[A0A1W2PRW4_HUMAN|Unreviewed]SubName: Full=HRAS-like suppressor 3 {ECO:0000313|Ensembl:ENSP00000492682};+++[F5H7E5_HUMAN|Unreviewed]SubName: Full=HRAS-like suppressor 3 {ECO:0000313|Ensembl:ENSP00000442576}; Flags: Fragment;+++[Q3MI98_HUMAN|Unreviewed]SubName: Full=PLA2G16 protein {ECO:0000313|EMBL:AAI03809.1}; Flags: Fragment;"]
[11158,"'RABL2B'",668.94,646.38,656.25,657.19,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0000242///pericentriolar material+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0005814///centriole+++GO:0042995///cell projection","GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0006886///intracellular protein transport+++GO:0032482///Rab protein signal transduction+++GO:0060271///cilium assembly+++GO:0042073///intraciliary transport+++GO:0030030///cell projection organization","RAB, member of RAS oncogene family like 2B","[RBL2B_HUMAN|Reviewed]RecName: Full=Rab-like protein 2B;+++[A0A0S2SW46_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|EMBL:ALP46109.1};+++[A8MXF6_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000378956};+++[C9JFZ0_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000415180}; Flags: Fragment;+++[F2Z2T3_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000378955};+++[F2Z3A9_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000419811};+++[F2Z3J7_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000398282};"]
[11179,"'ZNF277'",154,120,140,138,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0070301///cellular response to hydrogen peroxide+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000772///regulation of cellular senescence","zinc finger protein 277","[ZN277_HUMAN|Reviewed]RecName: Full=Zinc finger protein 277; AltName: Full=Nuclear receptor-interacting factor 4;+++[A4D0S7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein (C2H2 type) 277 {ECO:0000313|EMBL:EAL24376.1}; SubName: Full=cDNA, FLJ95473, Homo sapiens zinc finger protein (C2H2 type) 277 (ZNF277), mRNA {ECO:0000313|EMBL:BAG37195.1};+++[C9J3B6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 277 {ECO:0000313|Ensembl:ENSP00000410538};+++[C9JH62_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 277 {ECO:0000313|Ensembl:ENSP00000390359}; Flags: Fragment;+++[E7EW13_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 277 {ECO:0000313|Ensembl:ENSP00000355043};+++[F8WBE4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 277 {ECO:0000313|Ensembl:ENSP00000402846};+++[G5E9M4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 277, isoform CRA_a {ECO:0000313|EMBL:EAW83457.1};+++[H7C460_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 277 {ECO:0000313|Ensembl:ENSP00000415735}; Flags: Fragment;+++[Q75MZ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZNF277 {ECO:0000313|EMBL:AAS07408.1}; Flags: Fragment;+++[Q8WWA6_HUMAN|Unreviewed]SubName: Full=ZNF277 protein {ECO:0000313|EMBL:AAH20626.1};"]
[11194,"'ABCB8'",795,842,802,813,"02010///ABC transporters",{"$nulls":3},"GO:0005740///mitochondrial envelope+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005739///mitochondrion","GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity","GO:0055085///transmembrane transport","ATP binding cassette subfamily B member 8","[ABCB8_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family B member 8, mitochondrial; AltName: Full=Mitochondrial ATP-binding cassette 1; Short=M-ABC1; Flags: Precursor;+++[C9JA03_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 8, mitochondrial {ECO:0000313|Ensembl:ENSP00000417563}; Flags: Fragment;+++[C9JTY4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 8, mitochondrial {ECO:0000313|Ensembl:ENSP00000419558}; SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 8, isoform CRA_c {ECO:0000313|EMBL:EAW54058.1};+++[C9JYI3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 8, mitochondrial {ECO:0000313|Ensembl:ENSP00000419891};+++[F2Z2Z1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 8, mitochondrial {ECO:0000313|Ensembl:ENSP00000420631};+++[F2Z3G8_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 8, mitochondrial {ECO:0000313|Ensembl:ENSP00000418316};+++[F8WC43_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 8, mitochondrial {ECO:0000313|Ensembl:ENSP00000418970};+++[H7C5K9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 8, mitochondrial {ECO:0000313|Ensembl:ENSP00000420162}; Flags: Fragment;+++[L8EAK9_HUMAN|Unreviewed]SubName: Full=Alternative protein ABCB8 {ECO:0000313|EMBL:CCQ43393.1};"]
[11222,"'MRPL3'",834,810,927,857,"03010///Ribosome","H00891///Combined oxidative phosphorylation deficiency (COXPD)","M00179///Ribosome, archaea+++M00178///Ribosome, bacteria",null,"GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070126///mitochondrial translational termination+++GO:0006412///translation+++GO:0070125///mitochondrial translational elongation","mitochondrial ribosomal protein L3","[RM03_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L3, mitochondrial; Short=L3mt; Short=MRP-L3; AltName: Full=Mitochondrial large ribosomal subunit protein uL3m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[D6RBQ5_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L3, mitochondrial {ECO:0000313|Ensembl:ENSP00000422622}; Flags: Fragment;+++[D6RC14_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L3, mitochondrial {ECO:0000313|Ensembl:ENSP00000422419}; Flags: Fragment;+++[E7ETU7_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L3, mitochondrial {ECO:0000313|Ensembl:ENSP00000398536};+++[E9PF06_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L3, mitochondrial {ECO:0000313|Ensembl:ENSP00000422035}; Flags: Fragment;+++[H0Y9G6_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L3, mitochondrial {ECO:0000313|Ensembl:ENSP00000424107}; Flags: Fragment;+++[Q96Q75_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein L3 {ECO:0000313|EMBL:BAB54926.1}; Flags: Fragment;"]
[112267959,"'LOC112267959'",1,0,0,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized protein C9orf85-like","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[112268184,"'LOC112268184'",1,2,1,1.33333333333333,"03013///RNA transport",{"$nulls":3},"GO:0010494///cytoplasmic stress granule+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0005643///nuclear pore+++GO:0005576///extracellular region+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0043657///host cell+++GO:0005634///nucleus+++GO:0071782///endoplasmic reticulum tubular network+++GO:0034399///nuclear periphery+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:1904813///ficolin-1-rich granule lumen+++GO:0035580///specific granule lumen","GO:0008565///protein transporter activity+++GO:0051879///Hsp90 protein binding+++GO:0070006///metalloaminopeptidase activity+++GO:0019899///enzyme binding+++GO:0008270///zinc ion binding+++GO:0003723///RNA binding+++GO:0004177///aminopeptidase activity+++GO:0019904///protein domain specific binding+++GO:0008139///nuclear localization sequence binding+++GO:0042277///peptide binding+++GO:0008536///Ran GTPase binding","GO:0043312///neutrophil degranulation+++GO:0045184///establishment of protein localization+++GO:0000060///protein import into nucleus, translocation+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0031291///Ran protein signal transduction+++GO:0006508///proteolysis+++GO:0090307///mitotic spindle assembly+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0075733///intracellular transport of virus+++GO:0006309///apoptotic DNA fragmentation+++GO:0007080///mitotic metaphase plate congression+++GO:0071456///cellular response to hypoxia+++GO:0040001///establishment of mitotic spindle localization+++GO:0006610///ribosomal protein import into nucleus+++GO:0000209///protein polyubiquitination+++GO:0019054///modulation by virus of host process+++GO:0043171///peptide catabolic process+++GO:0030953///astral microtubule organization+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0006606///protein import into nucleus","uncharacterized LOC112268184","[AMPE_PIG|diamond]RecName: Full=Glutamyl aminopeptidase; Short=EAP; EC=3.4.11.7; AltName: Full=Aminopeptidase A; Short=AP-A; AltName: CD_antigen=CD249;+++[IMB1_HUMAN|diamond]RecName: Full=Importin subunit beta-1; AltName: Full=Importin-90; AltName: Full=Karyopherin subunit beta-1; AltName: Full=Nuclear factor p97; AltName: Full=Pore targeting complex 97 kDa subunit; Short=PTAC97;+++[IMB1_MOUSE|diamond]RecName: Full=Importin subunit beta-1; AltName: Full=Karyopherin subunit beta-1; AltName: Full=Nuclear factor p97; AltName: Full=Pore targeting complex 97 kDa subunit; Short=PTAC97; AltName: Full=SCG;+++[IMB1_RAT|diamond]RecName: Full=Importin subunit beta-1; AltName: Full=Karyopherin subunit beta-1; AltName: Full=Nuclear factor p97; AltName: Full=Pore targeting complex 97 kDa subunit; Short=PTAC97;+++[IMB_DROME|diamond]RecName: Full=Importin subunit beta; AltName: Full=Karyopherin subunit beta; AltName: Full=Protein ketel;+++[IMB_XENLA|diamond]RecName: Full=Importin subunit beta {ECO:0000303|PubMed:18366719}; AltName: Full=Importin-90 {ECO:0000303|PubMed:7627554}; AltName: Full=Karyopherin subunit beta {ECO:0000303|PubMed:7878057}; AltName: Full=p97 {ECO:0000303|PubMed:7878057};+++[PSA_CAEEL|diamond]RecName: Full=Puromycin-sensitive aminopeptidase {ECO:0000303|PubMed:12930831}; Short=PSA {ECO:0000305}; EC=3.4.11.14 {ECO:0000305|PubMed:12930831}; AltName: Full=Cytosol alanyl aminopeptidase {ECO:0000305}; Short=AAP-S {ECO:0000305};+++[PSA_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;+++[PSAL_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase-like protein; EC=3.4.11.-;+++[PSA_MOUSE|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;"]
[112268198,"'LOC112268198'",17,25.06,27,23.02,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC112268198","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[112268381,"'LOC112268381'",694.77,705.97,596.05,665.596666666667,{"$nulls":4},"GO:0071944///cell periphery+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0002102///podosome","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005525///GTP binding","GO:0043065///positive regulation of apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0051493///regulation of cytoskeleton organization+++GO:0051496///positive regulation of stress fiber assembly+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0043547///positive regulation of GTPase activity+++GO:1904591///positive regulation of protein import+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043087///regulation of GTPase activity+++GO:0030036///actin cytoskeleton organization+++GO:0071803///positive regulation of podosome assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0002408///myeloid dendritic cell chemotaxis+++GO:0043507///positive regulation of JUN kinase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0035023///regulation of Rho protein signal transduction","rho guanine nucleotide exchange factor 5-like","[ARG35_HUMAN|diamond]RecName: Full=Rho guanine nucleotide exchange factor 35; AltName: Full=Rho guanine nucleotide exchange factor 5-like protein;+++[ARHG5_HUMAN|diamond]RecName: Full=Rho guanine nucleotide exchange factor 5; AltName: Full=Ephexin-3; AltName: Full=Guanine nucleotide regulatory protein TIM; AltName: Full=Oncogene TIM; AltName: Full=Transforming immortalized mammary oncogene; AltName: Full=p60 TIM;+++[ARHG5_MOUSE|diamond]RecName: Full=Rho guanine nucleotide exchange factor 5 {ECO:0000312|MGI:MGI:1858952};+++[ARHGJ_HUMAN|diamond]RecName: Full=Rho guanine nucleotide exchange factor 19; AltName: Full=Ephexin-2;+++[ARHGJ_MOUSE|diamond]RecName: Full=Rho guanine nucleotide exchange factor 19; AltName: Full=Ephexin-2; AltName: Full=Weakly similar to Rho GEF 5;"]
[11238,"'CA5B'",151.14,181.11,160.34,164.196666666667,"00910///Nitrogen metabolism","H01302///Hyperchlorhidrosis isolated (HCHLH)+++H01400///Secondary hyperammonemia+++H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)",null,"R00132///carbonate hydro-lyase (carbon-dioxide-forming); carbonic   Carbonic acid <=> CO2 + H2O+++R10092///carbonate hydro-lyase (carbon-dioxide-forming)   HCO3- + H+ <=> CO2 + H2O","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0046872///metal ion binding+++GO:0004089///carbonate dehydratase activity+++GO:0016829///lyase activity+++GO:0008270///zinc ion binding","GO:0009617///response to bacterium+++GO:0015701///bicarbonate transport","carbonic anhydrase 5B","[CAH5B_HUMAN|Reviewed]RecName: Full=Carbonic anhydrase 5B, mitochondrial; EC=4.2.1.1; AltName: Full=Carbonate dehydratase VB; AltName: Full=Carbonic anhydrase VB; Short=CA-VB; Flags: Precursor;+++[A0A024RBW9_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase VB, mitochondrial, isoform CRA_c {ECO:0000313|EMBL:EAW98898.1};+++[C9IZP3_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase 5B, mitochondrial {ECO:0000313|Ensembl:ENSP00000418622}; Flags: Fragment;+++[C9JA11_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase 5B, mitochondrial {ECO:0000313|Ensembl:ENSP00000417553}; Flags: Fragment;+++[H7C4G3_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase 5B, mitochondrial {ECO:0000313|Ensembl:ENSP00000417236}; Flags: Fragment;"]
[11249,"'NXPH2'",6,2,2,3.33333333333333,{"$nulls":4},"GO:0005576///extracellular region","GO:0003674///molecular_function+++GO:0005102///signaling receptor binding","GO:0007218///neuropeptide signaling pathway","neurexophilin 2","[NXPH2_HUMAN|Reviewed]RecName: Full=Neurexophilin-2; Flags: Precursor;+++[Q494R3_HUMAN|Unreviewed]RecName: Full=Neurexophilin {ECO:0000256|PIRNR:PIRNR038019};"]
[11267,"'SNF8'",723,777,773,757.666666666667,"04144///Endocytosis",null,"M00410///ESCRT-II complex",null,"GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0055037///recycling endosome+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0000814///ESCRT II complex+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0031902///late endosome membrane+++GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0016247///channel regulator activity+++GO:0047485///protein N-terminus binding+++GO:0008134///transcription factor binding+++GO:0008022///protein C-terminus binding","GO:0010628///positive regulation of gene expression+++GO:0061635///regulation of protein complex stability+++GO:0045022///early endosome to late endosome transport+++GO:0015031///protein transport+++GO:0010797///regulation of multivesicular body size involved in endosome transport+++GO:0036258///multivesicular body assembly+++GO:0042176///regulation of protein catabolic process+++GO:0071985///multivesicular body sorting pathway+++GO:1903543///positive regulation of exosomal secretion+++GO:0045732///positive regulation of protein catabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043328///protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0043405///regulation of MAP kinase activity+++GO:0016197///endosomal transport+++GO:0032456///endocytic recycling+++GO:0016236///macroautophagy","SNF8, ESCRT-II complex subunit","[SNF8_HUMAN|Reviewed]RecName: Full=Vacuolar-sorting protein SNF8; AltName: Full=ELL-associated protein of 30 kDa; AltName: Full=ESCRT-II complex subunit VPS22; Short=hVps22;+++[D6RBI1_HUMAN|Unreviewed]SubName: Full=Vacuolar-sorting protein SNF8 {ECO:0000313|Ensembl:ENSP00000422701};+++[D6RFY6_HUMAN|Unreviewed]SubName: Full=Vacuolar-sorting protein SNF8 {ECO:0000313|Ensembl:ENSP00000421390};+++[D6RJ86_HUMAN|Unreviewed]SubName: Full=Vacuolar-sorting protein SNF8 {ECO:0000313|Ensembl:ENSP00000427328};+++[H0Y8S5_HUMAN|Unreviewed]SubName: Full=Vacuolar-sorting protein SNF8 {ECO:0000313|Ensembl:ENSP00000421956}; Flags: Fragment;+++[I3L2X5_HUMAN|Unreviewed]SubName: Full=Vacuolar-sorting protein SNF8 {ECO:0000313|Ensembl:ENSP00000460001};+++[I3L457_HUMAN|Unreviewed]SubName: Full=Vacuolar-sorting protein SNF8 {ECO:0000313|Ensembl:ENSP00000460981};+++[K7EPV2_HUMAN|Unreviewed]SubName: Full=Vacuolar-sorting protein SNF8 {ECO:0000313|Ensembl:ENSP00000467548}; Flags: Fragment;"]
[11279,"'KLF8'",6.75,11,7,8.25,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016235///aggresome","GO:0046872///metal ion binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II","Kruppel like factor 8","[KLF8_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 8; AltName: Full=Basic krueppel-like factor 3; AltName: Full=Zinc finger protein 741;+++[A0A024R9X4_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 8, isoform CRA_a {ECO:0000313|EMBL:EAW93231.1};+++[Q05BZ3_HUMAN|Unreviewed]SubName: Full=KLF8 protein {ECO:0000313|EMBL:AAH31355.1}; SubName: Full=Krueppel-like factor 8 {ECO:0000313|Ensembl:ENSP00000431911}; SubName: Full=Kruppel-like factor 8, isoform CRA_b {ECO:0000313|EMBL:EAW93232.1};"]
[112942,"'CFAP36'",906,851,640,799,"04922///Glucagon signaling pathway+++04212///Longevity regulating pathway - worm",{"$nulls":3},"GO:0031514///motile cilium+++GO:0097546///ciliary base+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0047485///protein N-terminus binding","GO:0008150///biological_process","cilia and flagella associated protein 36","[CFA36_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 36 {ECO:0000312|HGNC:HGNC:30540}; AltName: Full=Coiled-coil domain-containing protein 104 {ECO:0000312|HGNC:HGNC:30540};+++[B5MC35_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 36 {ECO:0000313|Ensembl:ENSP00000385400};+++[B5MCA1_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 36 {ECO:0000313|Ensembl:ENSP00000385376};+++[B5MD16_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 36 {ECO:0000313|Ensembl:ENSP00000385972};"]
[11315,"'PARK7'",1117,1132,1110,1119.66666666667,"05012///Parkinson's disease","H01600///Parkinsonian syndrome+++H00057///Parkinson's disease (PD)",null,null,"GO:0005758///mitochondrial intermembrane space+++GO:0044297///cell body+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0016605///PML body+++GO:0000785///chromatin+++GO:0098793///presynapse+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005913///cell-cell adherens junction+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0045121///membrane raft+++GO:0005654///nucleoplasm+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005783///endoplasmic reticulum+++GO:0030424///axon+++GO:0005739///mitochondrion","GO:0097110///scaffold protein binding+++GO:0003697///single-stranded DNA binding+++GO:0019955///cytokine binding+++GO:0019899///enzyme binding+++GO:0045340///mercury ion binding+++GO:0016532///superoxide dismutase copper chaperone activity+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding+++GO:0036524///protein deglycase activity+++GO:0051920///peroxiredoxin activity+++GO:0005507///copper ion binding+++GO:0003713///transcription coactivator activity+++GO:0036478///L-dopa decarboxylase activator activity+++GO:1903135///cupric ion binding+++GO:0036470///tyrosine 3-monooxygenase activator activity+++GO:0050681///androgen receptor binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0019900///kinase binding+++GO:0042803///protein homodimerization activity+++GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0070491///repressing transcription factor binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0044388///small protein activating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0016787///hydrolase activity+++GO:1903136///cuprous ion binding+++GO:0008134///transcription factor binding+++GO:0003690///double-stranded DNA binding+++GO:0001047///core promoter binding+++GO:0005102///signaling receptor binding","GO:0032148///activation of protein kinase B activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0036528///peptidyl-lysine deglycation+++GO:0060548///negative regulation of cell death+++GO:1901215///negative regulation of neuron death+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:1903122///negative regulation of TRAIL-activated apoptotic signaling pathway+++GO:0098869///cellular oxidant detoxification+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009438///methylglyoxal metabolic process+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0031397///negative regulation of protein ubiquitination+++GO:1902958///positive regulation of mitochondrial electron transport, NADH to ubiquinone+++GO:0051583///dopamine uptake involved in synaptic transmission+++GO:0010273///detoxification of copper ion+++GO:0034614///cellular response to reactive oxygen species+++GO:0033234///negative regulation of protein sumoylation+++GO:0030073///insulin secretion+++GO:1903384///negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0106045///guanine deglycation, methylglyoxal removal+++GO:0006914///autophagy+++GO:0018323///enzyme active site formation via L-cysteine sulfinic acid+++GO:0070301///cellular response to hydrogen peroxide+++GO:2000825///positive regulation of androgen receptor activity+++GO:0036531///glutathione deglycation+++GO:1903189///glyoxal metabolic process+++GO:1903094///negative regulation of protein K48-linked deubiquitination+++GO:0042743///hydrogen peroxide metabolic process+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:0001963///synaptic transmission, dopaminergic+++GO:0007265///Ras protein signal transduction+++GO:1902903///regulation of supramolecular fiber organization+++GO:0050821///protein stabilization+++GO:0002866///positive regulation of acute inflammatory response to antigenic stimulus+++GO:0007005///mitochondrion organization+++GO:0060081///membrane hyperpolarization+++GO:1903178///positive regulation of tyrosine 3-monooxygenase activity+++GO:1903181///positive regulation of dopamine biosynthetic process+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:1903200///positive regulation of L-dopa decarboxylase activity+++GO:0010628///positive regulation of gene expression+++GO:0006469///negative regulation of protein kinase activity+++GO:0036471///cellular response to glyoxal+++GO:0042177///negative regulation of protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0006508///proteolysis+++GO:1903377///negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:0036526///peptidyl-cysteine deglycation+++GO:0034599///cellular response to oxidative stress+++GO:0043523///regulation of neuron apoptotic process+++GO:1903073///negative regulation of death-inducing signaling complex assembly+++GO:0090073///positive regulation of protein homodimerization activity+++GO:0036530///protein deglycation, methylglyoxal removal+++GO:0007338///single fertilization+++GO:0106044///guanine deglycation+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0046295///glycolate biosynthetic process+++GO:0042542///response to hydrogen peroxide+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:1905259///negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway+++GO:1903197///positive regulation of L-dopa biosynthetic process+++GO:0051899///membrane depolarization+++GO:0045560///regulation of TRAIL receptor biosynthetic process+++GO:0006281///DNA repair+++GO:1903202///negative regulation of oxidative stress-induced cell death+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0050727///regulation of inflammatory response+++GO:0019249///lactate biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0008344///adult locomotory behavior+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0006517///protein deglycosylation+++GO:0006954///inflammatory response+++GO:2000277///positive regulation of oxidative phosphorylation uncoupler activity+++GO:1903168///positive regulation of pyrroline-5-carboxylate reductase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:2000157///negative regulation of ubiquitin-specific protease activity+++GO:0032091///negative regulation of protein binding+++GO:1902177///positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0042593///glucose homeostasis+++GO:0106046///guanine deglycation, glyoxal removal+++GO:0050787///detoxification of mercury ion+++GO:0046826///negative regulation of protein export from nucleus+++GO:0032757///positive regulation of interleukin-8 production+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0036527///peptidyl-arginine deglycation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:1901984///negative regulation of protein acetylation+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0036529///protein deglycation, glyoxal removal","Parkinsonism associated deglycase","[PARK7_HUMAN|Reviewed]RecName: Full=Protein/nucleic acid deglycase DJ-1 {ECO:0000305|PubMed:25416785, ECO:0000305|PubMed:28596309}; EC=3.1.2.- {ECO:0000269|PubMed:25416785}; EC=3.5.1.- {ECO:0000269|PubMed:28596309}; EC=3.5.1.124 {ECO:0000269|PubMed:25416785}; AltName: Full=Maillard deglycase {ECO:0000303|PubMed:28596309}; AltName: Full=Oncogene DJ1 {ECO:0000305}; AltName: Full=Parkinson disease protein 7 {ECO:0000305}; AltName: Full=Parkinsonism-associated deglycase {ECO:0000312|HGNC:HGNC:16369}; AltName: Full=Protein DJ-1 {ECO:0000305}; Short=DJ-1; Flags: Precursor;+++[K7ELW0_HUMAN|Unreviewed]SubName: Full=Protein/nucleic acid deglycase DJ-1 {ECO:0000313|Ensembl:ENSP00000466242};+++[K7EN27_HUMAN|Unreviewed]SubName: Full=Protein/nucleic acid deglycase DJ-1 {ECO:0000313|Ensembl:ENSP00000466756}; Flags: Fragment;+++[V9HWC2_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 67p {ECO:0000313|EMBL:ACJ13695.1};"]
[113235,"'SLC46A1'",811,1148,897,952,"01523///Antifolate resistance","H01252///Hereditary folate malabsorption (HFM)",null,null,"GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0015232///heme transporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0015350///methotrexate transmembrane transporter activity+++GO:0005542///folic acid binding+++GO:0005215///transporter activity+++GO:0008517///folic acid transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0051958///methotrexate transport+++GO:1902600///proton transmembrane transport+++GO:1904447///folate import across plasma membrane+++GO:0006879///cellular iron ion homeostasis+++GO:0015884///folic acid transport+++GO:0015886///heme transport+++GO:0046655///folic acid metabolic process+++GO:0098829///intestinal folate absorption","solute carrier family 46 member 1","[PCFT_HUMAN|Reviewed]RecName: Full=Proton-coupled folate transporter; AltName: Full=G21; AltName: Full=Heme carrier protein 1; AltName: Full=PCFT/HCP1; AltName: Full=Solute carrier family 46 member 1;+++[A0A024QZ15_HUMAN|Unreviewed]SubName: Full=Heme carrier protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW51087.1};+++[A0A024QZ44_HUMAN|Unreviewed]SubName: Full=Heme carrier protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW51089.1};+++[J3KTE6_HUMAN|Unreviewed]SubName: Full=Proton-coupled folate transporter {ECO:0000313|Ensembl:ENSP00000462942}; Flags: Fragment;+++[J3QL21_HUMAN|Unreviewed]SubName: Full=Proton-coupled folate transporter {ECO:0000313|Ensembl:ENSP00000463339}; Flags: Fragment;+++[J3QRF7_HUMAN|Unreviewed]SubName: Full=Proton-coupled folate transporter {ECO:0000313|Ensembl:ENSP00000464190}; Flags: Fragment;+++[K7EPJ7_HUMAN|Unreviewed]SubName: Full=Proton-coupled folate transporter {ECO:0000313|Ensembl:ENSP00000467416}; Flags: Fragment;"]
[11340,"'EXOSC8'",114,127,123,121.333333333333,"03018///RNA degradation","H00897///Pontocerebellar hypoplasia","M00391///Exosome, eukaryotes",null,"GO:0000178///exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0005654///nucleoplasm+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004532///exoribonuclease activity+++GO:0017091///AU-rich element binding","GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process+++GO:0008150///biological_process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034476///U5 snRNA 3'-end processing+++GO:0006364///rRNA processing+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0016075///rRNA catabolic process+++GO:0034473///U1 snRNA 3'-end processing+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0043488///regulation of mRNA stability+++GO:0006401///RNA catabolic process+++GO:0071028///nuclear mRNA surveillance+++GO:0034475///U4 snRNA 3'-end processing+++GO:0006396///RNA processing","exosome component 8","[EXOS8_HUMAN|Reviewed]RecName: Full=Exosome complex component RRP43; AltName: Full=Exosome component 8; AltName: Full=Opa-interacting protein 2; Short=OIP-2; AltName: Full=Ribosomal RNA-processing protein 43; AltName: Full=p9;+++[H7C581_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP43 {ECO:0000313|Ensembl:ENSP00000419203}; Flags: Fragment;+++[H7C5Z2_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP43 {ECO:0000313|Ensembl:ENSP00000239893};"]
[1135,"'CHRNA2'",0,2,2,1.33333333333333,"04080///Neuroactive ligand-receptor interaction","H00807///Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)",null,null,"GO:0045202///synapse+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045211///postsynaptic membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0016021///integral component of membrane+++GO:0071944///cell periphery","GO:0042166///acetylcholine binding+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0008144///drug binding+++GO:0005216///ion channel activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005230///extracellular ligand-gated ion channel activity","GO:0006811///ion transport+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0007165///signal transduction+++GO:0051291///protein heterooligomerization+++GO:0060079///excitatory postsynaptic potential+++GO:0034220///ion transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process+++GO:0007268///chemical synaptic transmission","cholinergic receptor nicotinic alpha 2 subunit","[ACHA2_HUMAN|Reviewed]RecName: Full=Neuronal acetylcholine receptor subunit alpha-2; Flags: Precursor;+++[A0A0X1KG79_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000429616};+++[A0A1B0GVX5_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000490690};+++[E5RGP6_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000429953}; Flags: Fragment;+++[E5RGT4_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000430994}; Flags: Fragment;+++[E5RHQ4_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000430856}; Flags: Fragment;+++[E5RJ54_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000430612};+++[E5RK67_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000430422}; Flags: Fragment;"]
[114034,"'TOE1'",92,104,111,102.333333333333,null,"H00897///Pontocerebellar hypoplasia",null,null,"GO:0005654///nucleoplasm+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0017069///snRNA binding+++GO:0046872///metal ion binding","GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0034472///snRNA 3'-end processing","target of EGR1, exonuclease","[TOE1_HUMAN|Reviewed]RecName: Full=Target of EGR1 protein 1;"]
[1145,"'CHRNE'",13,7,15,11.6666666666667,"04080///Neuroactive ligand-receptor interaction","H00770///Congenital myasthenic syndrome",null,null,"GO:0031594///neuromuscular junction+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane+++GO:0045202///synapse","GO:0005216///ion channel activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0008324///cation transmembrane transporter activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity+++GO:0042166///acetylcholine binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential","GO:0034220///ion transmembrane transport+++GO:0006811///ion transport+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0007165///signal transduction+++GO:0007274///neuromuscular synaptic transmission+++GO:0098655///cation transmembrane transport+++GO:0050877///nervous system process+++GO:0006936///muscle contraction+++GO:0007268///chemical synaptic transmission+++GO:0007271///synaptic transmission, cholinergic+++GO:0035094///response to nicotine+++GO:0060079///excitatory postsynaptic potential+++GO:0042391///regulation of membrane potential","cholinergic receptor nicotinic epsilon subunit","[ACHE_HUMAN|Reviewed]RecName: Full=Acetylcholine receptor subunit epsilon; Flags: Precursor;+++[Q8N731_HUMAN|Unreviewed]SubName: Full=AchR epsilon subunit {ECO:0000313|EMBL:BAB97270.1}; Flags: Fragment;"]
[114786,"'XKR4'",26,14,20,20,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"XK related 4","[XKR4_HUMAN|Reviewed]RecName: Full=XK-related protein 4;"]
[114826,"'SMYD4'",127.87,172.03,148.47,149.456666666667,"04137///Mitophagy - animal+++03430///Mismatch repair+++04310///Wnt signaling pathway+++03460///Fanconi anemia pathway+++03420///Nucleotide excision repair+++03030///DNA replication+++03440///Homologous recombination+++04140///Autophagy - animal","H00506///Osteogenesis imperfecta","M00288///RPA complex",null,"GO:0016605///PML body+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0043203///axon hillock+++GO:0042470///melanosome+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005576///extracellular region+++GO:0005662///DNA replication factor A complex+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0090734///site of DNA damage+++GO:0048471///perinuclear region of cytoplasm","GO:0046872///metal ion binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity","GO:0032259///methylation","SET and MYND domain containing 4","[SMYD4_HUMAN|Reviewed]RecName: Full=SET and MYND domain-containing protein 4; EC=2.1.1.-;+++[I3L1V4_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000459129};+++[I3L2P4_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000459819}; Flags: Fragment;+++[I3L428_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000460921}; Flags: Fragment;+++[I3L496_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000461089}; Flags: Fragment;"]
[114884,"'OSBPL10'",2398,2281,2138,2272.33333333333,"04141///Protein processing in endoplasmic reticulum+++01100///Metabolic pathways+++04140///Autophagy - animal+++00513///Various types of N-glycan biosynthesis+++00510///N-Glycan biosynthesis+++04137///Mitophagy - animal","H00118///Congenital disorders of glycosylation (CDG) type I","M00072///N-glycosylation by oligosaccharyltransferase","R05976///Protein asparagine + G00008 <=> Dolichyl diphosphate + G00009+++R04216///dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase Dolichyl diphosphooligosaccharide + Protein asparagine <=> Dolichyl diphosphate + Glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine","GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0015485///cholesterol binding+++GO:0032934///sterol binding+++GO:0001786///phosphatidylserine binding+++GO:0015248///sterol transporter activity+++GO:0008289///lipid binding+++GO:0005548///phospholipid transporter activity","GO:0015918///sterol transport+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0006869///lipid transport+++GO:0015914///phospholipid transport+++GO:0006629///lipid metabolic process","oxysterol binding protein like 10","[OSB10_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 10; Short=ORP-10; Short=OSBP-related protein 10;+++[H7C199_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 10 {ECO:0000313|Ensembl:ENSP00000399200}; Flags: Fragment;+++[H7C487_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;+++[Q9NX98_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};"]
[115098,"'CCDC124'",1769,1643,1521,1644.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005886///plasma membrane","GO:0003723///RNA binding","GO:0007049///cell cycle+++GO:0051301///cell division","coiled-coil domain containing 124","[CC124_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 124;+++[A0A024R7M8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW84645.1};+++[M0R2F5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 124 {ECO:0000313|Ensembl:ENSP00000472520}; Flags: Fragment;"]
[115209,"'OMA1'",90,79,69,79.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++03040///Spliceosome","H00058///Amyotrophic lateral sclerosis (ALS)+++H02031///Inclusion body myopathy with Paget disease of bone and frontotemporal dementia",null,null,"GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane","GO:0016787///hydrolase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding","GO:0002024///diet induced thermogenesis+++GO:0034982///mitochondrial protein processing+++GO:0007005///mitochondrion organization+++GO:0006629///lipid metabolic process+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0042407///cristae formation+++GO:0006006///glucose metabolic process+++GO:0006508///proteolysis+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0042981///regulation of apoptotic process+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0097009///energy homeostasis","OMA1 zinc metallopeptidase","[OMA1_HUMAN|Reviewed]RecName: Full=Metalloendopeptidase OMA1, mitochondrial; EC=3.4.24.-; AltName: Full=Metalloprotease-related protein 1; Short=MPRP-1; AltName: Full=Overlapping with the m-AAA protease 1 homolog; Flags: Precursor;+++[H7BZX2_HUMAN|Unreviewed]SubName: Full=Metalloendopeptidase OMA1, mitochondrial {ECO:0000313|Ensembl:ENSP00000391941}; Flags: Fragment;+++[S4R3A3_HUMAN|Unreviewed]SubName: Full=Metalloendopeptidase OMA1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474081}; Flags: Fragment;+++[X6RD49_HUMAN|Unreviewed]SubName: Full=Metalloendopeptidase OMA1, mitochondrial {ECO:0000313|Ensembl:ENSP00000392978}; Flags: Fragment;+++[X6RDQ1_HUMAN|Unreviewed]SubName: Full=Metalloendopeptidase OMA1, mitochondrial {ECO:0000313|Ensembl:ENSP00000395053}; Flags: Fragment;+++[X6RIG5_HUMAN|Unreviewed]SubName: Full=Metalloendopeptidase OMA1, mitochondrial {ECO:0000313|Ensembl:ENSP00000409589}; Flags: Fragment;+++[X6RL62_HUMAN|Unreviewed]SubName: Full=Metalloendopeptidase OMA1, mitochondrial {ECO:0000313|Ensembl:ENSP00000416495}; Flags: Fragment;"]
[1155,"'TBCB'",1006,929,890,941.666666666667,{"$nulls":4},"GO:0015630///microtubule cytoskeleton+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005515///protein binding","GO:0030154///cell differentiation+++GO:0007399///nervous system development+++GO:0007275///multicellular organism development","tubulin folding cofactor B","[TBCB_HUMAN|Reviewed]RecName: Full=Tubulin-folding cofactor B; AltName: Full=Cytoskeleton-associated protein 1; AltName: Full=Cytoskeleton-associated protein CKAPI; AltName: Full=Tubulin-specific chaperone B;+++[K7EK42_HUMAN|Unreviewed]SubName: Full=Tubulin-folding cofactor B {ECO:0000313|Ensembl:ENSP00000465447};+++[K7EL99_HUMAN|Unreviewed]SubName: Full=Tubulin-folding cofactor B {ECO:0000313|Ensembl:ENSP00000465979}; Flags: Fragment;+++[K7EP07_HUMAN|Unreviewed]SubName: Full=Tubulin-folding cofactor B {ECO:0000313|Ensembl:ENSP00000467172}; Flags: Fragment;+++[K7EQH0_HUMAN|Unreviewed]SubName: Full=Tubulin-folding cofactor B {ECO:0000313|Ensembl:ENSP00000467825};+++[K7ER04_HUMAN|Unreviewed]SubName: Full=Tubulin-folding cofactor B {ECO:0000313|Ensembl:ENSP00000468055};"]
[115708,"'TRMT61A'",413,370,358,380.333333333333,{"$nulls":4},"GO:0031515///tRNA (m1A) methyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0061953///mRNA (adenine-N1-)-methyltransferase activity+++GO:0016429///tRNA (adenine-N1-)-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity","GO:0032259///methylation+++GO:0030488///tRNA methylation+++GO:0008033///tRNA processing+++GO:0080009///mRNA methylation","tRNA methyltransferase 61A","[TRM61_HUMAN|Reviewed]RecName: Full=tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; EC=2.1.1.220 {ECO:0000269|PubMed:16043508}; AltName: Full=mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A {ECO:0000303|PubMed:29072297}; EC=2.1.1.- {ECO:0000269|PubMed:29072297, ECO:0000269|PubMed:29107537}; AltName: Full=tRNA(m1A58)-methyltransferase subunit TRMT61A; Short=tRNA(m1A58)MTase subunit TRMT61A;+++[A0A024R6Q2_HUMAN|Unreviewed]RecName: Full=tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A {ECO:0000256|PIRNR:PIRNR017269}; EC=2.1.1.220 {ECO:0000256|PIRNR:PIRNR017269};+++[H0Y2Q1_HUMAN|Unreviewed]SubName: Full=tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A {ECO:0000313|Ensembl:ENSP00000299202}; Flags: Fragment;+++[Q96B39_HUMAN|Unreviewed]SubName: Full=TRMT61A protein {ECO:0000313|EMBL:AAH16033.2}; Flags: Fragment;"]
[116092,"'DNTTIP1'",357,399,345,367,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0000118///histone deacetylase complex+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0031491///nucleosome binding","GO:0006351///transcription, DNA-templated+++GO:0015031///protein transport+++GO:0006355///regulation of transcription, DNA-templated","deoxynucleotidyltransferase terminal interacting protein 1","[TDIF1_HUMAN|Reviewed]RecName: Full=Deoxynucleotidyltransferase terminal-interacting protein 1; AltName: Full=Terminal deoxynucleotidyltransferase-interacting factor 1; Short=TdIF1 {ECO:0000303|PubMed:11473582, ECO:0000303|PubMed:23874396}; Short=TdT-interacting factor 1 {ECO:0000303|PubMed:11473582};+++[F2Z2A4_HUMAN|Unreviewed]SubName: Full=Deoxynucleotidyltransferase terminal-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000392509}; Flags: Fragment;+++[H0Y501_HUMAN|Unreviewed]SubName: Full=Deoxynucleotidyltransferase terminal-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000395609}; Flags: Fragment;+++[H7C1J2_HUMAN|Unreviewed]SubName: Full=Deoxynucleotidyltransferase terminal-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000400573}; Flags: Fragment;+++[H7C1M5_HUMAN|Unreviewed]SubName: Full=Deoxynucleotidyltransferase terminal-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000401024}; Flags: Fragment;"]
[116224,"'FAM122A'",273,258,257,262.666666666667,{"$nulls":5},"GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0005515///protein binding","GO:0030307///positive regulation of cell growth+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process","family with sequence similarity 122A","[F122A_HUMAN|Reviewed]RecName: Full=Protein FAM122A;+++[B3KX07_HUMAN|Unreviewed]SubName: Full=cDNA FLJ44415 fis, clone UTERU1000384 {ECO:0000313|EMBL:BAG54319.1};"]
[116534,"'MRGPRE'",0,1,2,1,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","MAS related GPR family member E","[MRGRE_HUMAN|Reviewed]RecName: Full=Mas-related G-protein coupled receptor member E; AltName: Full=G-protein coupled receptor 167;+++[L8E724_HUMAN|Unreviewed]SubName: Full=Alternative protein MRGPRE {ECO:0000313|EMBL:CCQ43050.1};+++[W4VSQ4_HUMAN|Unreviewed]SubName: Full=HCG2039161 {ECO:0000313|EMBL:EAX02547.1}; SubName: Full=Mas-related G protein-coupled receptor F {ECO:0000313|EMBL:CDG86186.1};"]
[116984,"'ARAP2'",192,144,146,160.666666666667,"04144///Endocytosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005096///GTPase activator activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2","[ARAP2_HUMAN|Reviewed]RecName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2; AltName: Full=Centaurin-delta-1; Short=Cnt-d1; AltName: Full=Protein PARX;+++[A0A0C4DGW1_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000481036};+++[A0A2X0SFS3_HUMAN|Unreviewed]SubName: Full=ARAP2 {ECO:0000313|EMBL:SPT35675.1}; Flags: Fragment;+++[A7E2A5_HUMAN|Unreviewed]SubName: Full=ARAP2 protein {ECO:0000313|EMBL:AAI50259.1}; Flags: Fragment;+++[D6RAD6_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422731}; Flags: Fragment;+++[D6RC39_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423886}; Flags: Fragment;+++[Q2M2Z8_HUMAN|Unreviewed]SubName: Full=ARAP2 protein {ECO:0000313|EMBL:AAI05090.1}; Flags: Fragment;"]
[117178,"'SSX2IP'",444,351,385,393.333333333333,"04520///Adherens junction",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005815///microtubule organizing center+++GO:0042995///cell projection+++GO:0030054///cell junction+++GO:0034451///centriolar satellite+++GO:0005634///nucleus+++GO:0036064///ciliary basal body+++GO:0005737///cytoplasm+++GO:0031252///cell leading edge+++GO:0005913///cell-cell adherens junction+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction","GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0060271///cilium assembly+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0030030///cell projection organization+++GO:0035020///regulation of Rac protein signal transduction+++GO:0007098///centrosome cycle+++GO:0007155///cell adhesion+++GO:2000145///regulation of cell motility","SSX family member 2 interacting protein","[ADIP_HUMAN|Reviewed]RecName: Full=Afadin- and alpha-actinin-binding protein; Short=ADIP; AltName: Full=Afadin DIL domain-interacting protein; AltName: Full=SSX2-interacting protein;+++[B7ZB07_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79371, highly similar to Afadin- and alpha-actinin-binding protein {ECO:0000313|EMBL:BAH14843.1};+++[C9JIX7_HUMAN|Unreviewed]SubName: Full=Afadin- and alpha-actinin-binding protein {ECO:0000313|Ensembl:ENSP00000416067}; Flags: Fragment;+++[S4R2Y6_HUMAN|Unreviewed]SubName: Full=Afadin- and alpha-actinin-binding protein {ECO:0000313|Ensembl:ENSP00000473763};+++[S4R403_HUMAN|Unreviewed]SubName: Full=Afadin- and alpha-actinin-binding protein {ECO:0000313|Ensembl:ENSP00000474925};"]
[1182,"'CLCN3'",1599,1548,1587,1578,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02147///X-linked recessive nephrolithiasis with renal failure+++H00694///Dent disease+++H00480///Non-syndromic X-linked mental retardation+++H00214///Hypophosphatemic rickets+++H02148///Low molecular weight proteinuria with hypercalciuria and nephrocalcinosis+++H02149///X-linked hypercalciuric nephrolithiasis+++H02142///X-linked recessive hypophosphatemic rickets",null,null,"GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0045335///phagocytic vesicle+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0009897///external side of plasma membrane+++GO:0012506///vesicle membrane+++GO:0031902///late endosome membrane+++GO:0005770///late endosome+++GO:0030658///transport vesicle membrane+++GO:0005769///early endosome+++GO:0098982///GABA-ergic synapse+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0042581///specific granule+++GO:0016020///membrane+++GO:0008021///synaptic vesicle","GO:0005254///chloride channel activity+++GO:0042803///protein homodimerization activity+++GO:0031404///chloride ion binding+++GO:0030165///PDZ domain binding+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005515///protein binding+++GO:0072320///volume-sensitive chloride channel activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0046982///protein heterodimerization activity","GO:0048388///endosomal lumen acidification+++GO:0097401///synaptic vesicle lumen acidification+++GO:1902476///chloride transmembrane transport+++GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:0006885///regulation of pH+++GO:0045794///negative regulation of cell volume+++GO:0006821///chloride transport","chloride voltage-gated channel 3","[CLCN3_HUMAN|Reviewed]RecName: Full=H(+)/Cl(-) exchange transporter 3; AltName: Full=Chloride channel protein 3; Short=ClC-3; AltName: Full=Chloride transporter ClC-3;+++[A0A087WU31_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};+++[A0A0A0MTB7_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};+++[B3KXK0_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221}; Flags: Fragment;+++[D6RDZ6_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 3 {ECO:0000313|Ensembl:ENSP00000425160}; Flags: Fragment;+++[D6RIX3_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 3 {ECO:0000313|Ensembl:ENSP00000425823}; Flags: Fragment;+++[E9PE15_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221}; Flags: Fragment;+++[H0Y8Z8_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 3 {ECO:0000313|Ensembl:ENSP00000422678}; Flags: Fragment;+++[Q7Z4M4_HUMAN|Unreviewed]SubName: Full=CLCN3 protein {ECO:0000313|EMBL:AAH54877.1}; Flags: Fragment;"]
[118491,"'CFAP70'",30,43,26,33,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005929///cilium+++GO:0042995///cell projection+++GO:0070062///extracellular exosome","GO:0003674///molecular_function","GO:0008150///biological_process","cilia and flagella associated protein 70","[CFA70_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 70 {ECO:0000312|HGNC:HGNC:30726}; AltName: Full=Tetratricopeptide repeat protein 18 {ECO:0000305}; Short=TPR repeat protein 18 {ECO:0000305};+++[A0A087WSW1_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 70 {ECO:0000313|Ensembl:ENSP00000347781};+++[A0A0A0MS55_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 70 {ECO:0000313|Ensembl:ENSP00000378334};+++[X6R507_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 70 {ECO:0000313|Ensembl:ENSP00000343650};+++[X6RID7_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 70 {ECO:0000313|Ensembl:ENSP00000409527}; Flags: Fragment;"]
[119,"'ADD2'",346.21,194.01,178,239.406666666667,null,"H01097///Spastic quadriplegic cerebral palsy",null,null,"GO:0014069///postsynaptic density+++GO:0008290///F-actin capping protein complex+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0044853///plasma membrane raft+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle","GO:0046982///protein heterodimerization activity+++GO:0030507///spectrin binding+++GO:0051015///actin filament binding+++GO:0005198///structural molecule activity+++GO:0042803///protein homodimerization activity+++GO:0005516///calmodulin binding+++GO:0003779///actin binding+++GO:0019901///protein kinase binding","GO:0050900///leukocyte migration+++GO:0007416///synapse assembly+++GO:0055085///transmembrane transport+++GO:0065003///protein-containing complex assembly+++GO:0051016///barbed-end actin filament capping+++GO:0050901///leukocyte tethering or rolling+++GO:0032092///positive regulation of protein binding+++GO:0030036///actin cytoskeleton organization+++GO:0051017///actin filament bundle assembly+++GO:0030097///hemopoiesis","adducin 2","[ADDB_HUMAN|Reviewed]RecName: Full=Beta-adducin; AltName: Full=Erythrocyte adducin subunit beta;+++[A0A1C7CYY0_HUMAN|Unreviewed]SubName: Full=Beta-adducin {ECO:0000313|Ensembl:ENSP00000430243}; Flags: Fragment;+++[C9J080_HUMAN|Unreviewed]SubName: Full=Beta-adducin {ECO:0000313|Ensembl:ENSP00000412357}; Flags: Fragment;+++[C9J299_HUMAN|Unreviewed]SubName: Full=Beta-adducin {ECO:0000313|Ensembl:ENSP00000412681}; Flags: Fragment;+++[C9JJK3_HUMAN|Unreviewed]SubName: Full=Beta-adducin {ECO:0000313|Ensembl:ENSP00000403722}; Flags: Fragment;+++[C9JTM0_HUMAN|Unreviewed]SubName: Full=Beta-adducin {ECO:0000313|Ensembl:ENSP00000414546}; Flags: Fragment;+++[Q05DK5_HUMAN|Unreviewed]SubName: Full=ADD2 protein {ECO:0000313|EMBL:AAH10237.1}; Flags: Fragment;"]
[119710,"'C11orf74'",451,420,366,412.333333333333,{"$nulls":4},"GO:0005929///cilium","GO:0046872///metal ion binding+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding+++GO:0003727///single-stranded RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","chromosome 11 open reading frame 74","[CK074_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf74; AltName: Full=Protein HEPIS;+++[A8K468_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76614, highly similar to Homo sapiens HEPIS, mRNA {ECO:0000313|EMBL:BAF83522.1};+++[B4DYW4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51661 {ECO:0000313|EMBL:BAG63876.1};+++[E9PJ48_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf74 {ECO:0000313|Ensembl:ENSP00000435676}; Flags: Fragment;+++[E9PL16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf74 {ECO:0000313|Ensembl:ENSP00000433407}; Flags: Fragment;+++[E9PPH4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf74 {ECO:0000313|Ensembl:ENSP00000432685}; Flags: Fragment;"]
[120534,"'ARL14EP'",185,137,168,163.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005925///focal adhesion","GO:0005515///protein binding",null,"ADP ribosylation factor like GTPase 14 effector protein","[AL14E_HUMAN|Reviewed]RecName: Full=ARL14 effector protein; AltName: Full=ARF7 effector protein;+++[E9PRK7_HUMAN|Unreviewed]SubName: Full=ARL14 effector protein {ECO:0000313|Ensembl:ENSP00000432224}; Flags: Fragment;"]
[1213,"'CLTC'",4825,4371,4564,4586.66666666667,"05100///Bacterial invasion of epithelial cells+++05016///Huntington's disease+++04721///Synaptic vesicle cycle+++04142///Lysosome+++04144///Endocytosis+++04961///Endocrine and other factor-regulated calcium reabsorption",{"$nulls":3},"GO:0031523///Myb complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005819///spindle+++GO:1903561///extracellular vesicle+++GO:0005764///lysosome+++GO:0030117///membrane coat+++GO:0098835///presynaptic endocytic zone membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005856///cytoskeleton+++GO:0005768///endosome+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0030132///clathrin coat of coated pit+++GO:0030659///cytoplasmic vesicle membrane+++GO:1990498///mitotic spindle microtubule+++GO:0030669///clathrin-coated endocytic vesicle membrane+++GO:0030136///clathrin-coated vesicle+++GO:0016020///membrane+++GO:0071439///clathrin complex+++GO:0005737///cytoplasm+++GO:0032588///trans-Golgi network membrane+++GO:0005623///cell+++GO:0072686///mitotic spindle+++GO:0043209///myelin sheath+++GO:0098684///photoreceptor ribbon synapse+++GO:0032991///protein-containing complex+++GO:0030118///clathrin coat+++GO:0005829///cytosol+++GO:0036020///endolysosome membrane+++GO:0005905///clathrin-coated pit+++GO:0030130///clathrin coat of trans-Golgi network vesicle+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0042470///melanosome+++GO:0005886///plasma membrane","GO:0005198///structural molecule activity+++GO:1990381///ubiquitin-specific protease binding+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0019901///protein kinase binding+++GO:0032051///clathrin light chain binding+++GO:0003725///double-stranded RNA binding+++GO:0003723///RNA binding","GO:0034383///low-density lipoprotein particle clearance+++GO:0016192///vesicle-mediated transport+++GO:0033572///transferrin transport+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:0031623///receptor internalization+++GO:0001649///osteoblast differentiation+++GO:0007049///cell cycle+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0006886///intracellular protein transport+++GO:0051301///cell division+++GO:1900126///negative regulation of hyaluronan biosynthetic process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090307///mitotic spindle assembly+++GO:0061024///membrane organization+++GO:0006914///autophagy+++GO:0072583///clathrin-dependent endocytosis+++GO:0045056///transcytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0048268///clathrin coat assembly+++GO:0032802///low-density lipoprotein particle receptor catabolic process+++GO:0000278///mitotic cell cycle+++GO:0060236///regulation of mitotic spindle organization","clathrin heavy chain","[CLH1_HUMAN|Reviewed]RecName: Full=Clathrin heavy chain 1 {ECO:0000303|PubMed:26822784, ECO:0000303|PubMed:29100083}; AltName: Full=Clathrin heavy chain on chromosome 17; Short=CLH-17;+++[A0A087WVQ6_HUMAN|Unreviewed]RecName: Full=Clathrin heavy chain {ECO:0000256|PIRNR:PIRNR002290};+++[J3KRF5_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000461977}; Flags: Fragment;+++[J3KS13_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000462252};+++[J3KSQ2_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000462592}; Flags: Fragment;+++[J3KTN1_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000463068}; Flags: Fragment;+++[J3QL20_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000463336};+++[K7EJJ5_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000465200}; Flags: Fragment;+++[Q49AL0_HUMAN|Unreviewed]SubName: Full=CLTC protein {ECO:0000313|EMBL:AAH36430.1};"]
[122509,"'IFI27L1'",73,76,71,73.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005521///lamin binding","GO:0006915///apoptotic process+++GO:0097190///apoptotic signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process","interferon alpha inducible protein 27 like 1","[I27L1_HUMAN|Reviewed]RecName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000305}; AltName: Full=Interferon-stimulated gene 12c protein {ECO:0000303|PubMed:14728724}; Short=ISG12(c) {ECO:0000303|PubMed:14728724}; Short=ISG12C {ECO:0000303|PubMed:27673746};+++[G3V248_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000313|Ensembl:ENSP00000450463};+++[G3V2F0_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000313|Ensembl:ENSP00000450620};+++[G3V349_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000313|Ensembl:ENSP00000451043};+++[G3V3W3_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000313|Ensembl:ENSP00000451459};+++[G3V460_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000313|Ensembl:ENSP00000451608}; Flags: Fragment;+++[G3V4A1_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000313|Ensembl:ENSP00000451676};+++[G3V585_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27-like protein 1 {ECO:0000313|Ensembl:ENSP00000452226}; Flags: Fragment;"]
[122961,"'ISCA2'",304,253,271,276,null,"H01894///Multiple mitochondrial dysfunctions syndrome",null,null,"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0005198///structural molecule activity+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0005506///iron ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0044281///small molecule metabolic process+++GO:0016226///iron-sulfur cluster assembly+++GO:0051604///protein maturation+++GO:0097428///protein maturation by iron-sulfur cluster transfer","iron-sulfur cluster assembly 2","[ISCA2_HUMAN|Reviewed]RecName: Full=Iron-sulfur cluster assembly 2 homolog, mitochondrial; AltName: Full=HESB-like domain-containing protein 1; Flags: Precursor;+++[J3QSS7_HUMAN|Unreviewed]SubName: Full=Iron-sulfur cluster assembly 2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000298818};"]
[123591,"'TMEM266'",12,18,14,14.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane",null,null,"transmembrane protein 266","[TM266_HUMAN|Reviewed]RecName: Full=Transmembrane protein 266 {ECO:0000312|HGNC:HGNC:26763};+++[H0YNC9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 266 {ECO:0000313|Ensembl:ENSP00000453957};+++[H3BM28_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 266 {ECO:0000313|Ensembl:ENSP00000435049};"]
[123688,"'HYKK'",38,35,28.98,33.9933333333333,"00310///Lysine degradation+++01100///Metabolic pathways",null,null,"R03378///GTP:5-hydroxy-L-lysine O-phosphotransferase   GTP + L-Hydroxylysine <=> GDP + 5-Phosphooxy-L-lysine","GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0047992///hydroxylysine kinase activity","GO:0006554///lysine catabolic process+++GO:0016310///phosphorylation","hydroxylysine kinase","[HYKK_HUMAN|Reviewed]RecName: Full=Hydroxylysine kinase; Short=5-hydroxy-L-lysine kinase; EC=2.7.1.81; AltName: Full=Aminoglycoside phosphotransferase domain-containing protein 1;+++[A0A0C4DGM4_HUMAN|Unreviewed]SubName: Full=Hydroxylysine kinase {ECO:0000313|Ensembl:ENSP00000457154};"]
[124460,"'SNX20'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0031901///early endosome membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding","GO:0015031///protein transport","sorting nexin 20","[SNX20_HUMAN|Reviewed]RecName: Full=Sorting nexin-20; AltName: Full=Selectin ligand-interactor cytoplasmic 1 {ECO:0000303|PubMed:18196517}; Short=SLIC-1 {ECO:0000303|PubMed:18196517};+++[A0A087X2C1_HUMAN|Unreviewed]SubName: Full=Sorting nexin-20 {ECO:0000313|Ensembl:ENSP00000484863};"]
[124565,"'SLC38A10'",4517,4670,4451,4546,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0015171///amino acid transmembrane transporter activity","GO:0006865///amino acid transport+++GO:0006814///sodium ion transport+++GO:0003333///amino acid transmembrane transport+++GO:0060348///bone development+++GO:0006811///ion transport","solute carrier family 38 member 10","[S38AA_HUMAN|Reviewed]RecName: Full=Putative sodium-coupled neutral amino acid transporter 10; AltName: Full=Solute carrier family 38 member 10;+++[F5H3T4_HUMAN|Unreviewed]SubName: Full=Putative sodium-coupled neutral amino acid transporter 10 {ECO:0000313|Ensembl:ENSP00000439115}; Flags: Fragment;+++[H0YF92_HUMAN|Unreviewed]SubName: Full=Putative sodium-coupled neutral amino acid transporter 10 {ECO:0000313|Ensembl:ENSP00000437601}; Flags: Fragment;+++[H0YGS1_HUMAN|Unreviewed]SubName: Full=Putative sodium-coupled neutral amino acid transporter 10 {ECO:0000313|Ensembl:ENSP00000444523}; Flags: Fragment;+++[I3L0Q8_HUMAN|Unreviewed]SubName: Full=Putative sodium-coupled neutral amino acid transporter 10 {ECO:0000313|Ensembl:ENSP00000458273}; Flags: Fragment;+++[Q8WW39_HUMAN|Unreviewed]SubName: Full=SLC38A10 protein {ECO:0000313|EMBL:AAH20925.1}; Flags: Fragment;"]
[124995,"'MRPL10'",613,568,576,585.666666666667,"03010///Ribosome",null,"M00178///Ribosome, bacteria+++M00179///Ribosome, archaea",null,"GO:0005743///mitochondrial inner membrane+++GO:0015934///large ribosomal subunit+++GO:0005840///ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding","GO:0006412///translation+++GO:0042254///ribosome biogenesis+++GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination","mitochondrial ribosomal protein L10","[RM10_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L10, mitochondrial; Short=L10mt; Short=MRP-L10; AltName: Full=39S ribosomal protein L8, mitochondrial; Short=L8mt; Short=MRP-L8; AltName: Full=Mitochondrial large ribosomal subunit protein uL10m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[B4DEH0_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein L10, isoform CRA_d {ECO:0000313|EMBL:EAW94799.1}; SubName: Full=cDNA FLJ55192, highly similar to Homo sapiens mitochondrial ribosomal protein L10 (MRPL10), mRNA {ECO:0000313|EMBL:BAG57081.1};+++[F2Z2K7_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L10, mitochondrial {ECO:0000313|Ensembl:ENSP00000390624};"]
[124997,"'WDR81'",1145,1561,1301,1335.66666666667,null,"H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)",null,null,"GO:0031902///late endosome membrane+++GO:0031313///extrinsic component of endosome membrane+++GO:0000421///autophagosome membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0005764///lysosome+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle","GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0005515///protein binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding","GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0035973///aggrephagy+++GO:0050821///protein stabilization+++GO:0045022///early endosome to late endosome transport+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0007005///mitochondrion organization+++GO:0010923///negative regulation of phosphatase activity","WD repeat domain 81","[WDR81_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 81 {ECO:0000312|HGNC:HGNC:26600};+++[A0A0J9YXM6_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 81 {ECO:0000313|Ensembl:ENSP00000488468};+++[C9JCF9_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 81 {ECO:0000313|Ensembl:ENSP00000395226}; Flags: Fragment;+++[C9JD20_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 81 {ECO:0000313|Ensembl:ENSP00000395198}; Flags: Fragment;+++[E9PDG3_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 81 {ECO:0000313|Ensembl:ENSP00000401560};+++[I3L1G2_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 81 {ECO:0000313|Ensembl:ENSP00000458811}; Flags: Fragment;+++[I3L3U7_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 81 {ECO:0000313|Ensembl:ENSP00000460742}; Flags: Fragment;+++[K7ELV8_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 81 {ECO:0000313|Ensembl:ENSP00000466240}; Flags: Fragment;+++[Q24JR4_HUMAN|Unreviewed]SubName: Full=WDR81 protein {ECO:0000313|EMBL:AAI14520.1};"]
[126006,"'PCP2'",18,24,22,21.3333333333333,null,"H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0045335///phagocytic vesicle+++GO:0042581///specific granule+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0044194///cytolytic granule+++GO:0042582///azurophil granule+++GO:0005576///extracellular region+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0042589///zymogen granule membrane+++GO:0070820///tertiary granule","GO:0030695///GTPase regulator activity+++GO:0030348///syntaxin-3 binding+++GO:0017075///syntaxin-1 binding","GO:0001909///leukocyte mediated cytotoxicity+++GO:0071346///cellular response to interferon-gamma+++GO:0002576///platelet degranulation+++GO:0043312///neutrophil degranulation+++GO:0006904///vesicle docking involved in exocytosis+++GO:0015031///protein transport+++GO:0043304///regulation of mast cell degranulation","Purkinje cell protein 2","[PCP2_HUMAN|Reviewed]RecName: Full=Purkinje cell protein 2 homolog;+++[Q8IUH7_HUMAN|Unreviewed]SubName: Full=Purkinje cell-specific protein 2 long isoform A {ECO:0000313|EMBL:AAN52488.1}; Flags: Fragment;"]
[126123,"'IZUMO2'",0,2,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IZUMO family member 2","[IZUM2_HUMAN|Reviewed]RecName: Full=Izumo sperm-egg fusion protein 2; Flags: Precursor;+++[M0QXA9_HUMAN|Unreviewed]SubName: Full=Izumo sperm-egg fusion protein 2 {ECO:0000313|Ensembl:ENSP00000469026}; Flags: Fragment;+++[M0QZG1_HUMAN|Unreviewed]SubName: Full=Izumo sperm-egg fusion protein 2 {ECO:0000313|Ensembl:ENSP00000470525}; Flags: Fragment;+++[M0R2L8_HUMAN|Unreviewed]SubName: Full=Izumo sperm-egg fusion protein 2 {ECO:0000313|Ensembl:ENSP00000472657}; Flags: Fragment;"]
[126374,"'WTIP'",638,581,537,585.333333333333,"04392///Hippo signaling pathway - multiple species+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly",{"$nulls":3},"GO:0005912///adherens junction+++GO:0005911///cell-cell junction+++GO:0005737///cytoplasm+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0046872///metal ion binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0031047///gene silencing by RNA+++GO:0035331///negative regulation of hippo signaling+++GO:0001666///response to hypoxia+++GO:0007010///cytoskeleton organization+++GO:2000637///positive regulation of gene silencing by miRNA+++GO:0035195///gene silencing by miRNA+++GO:0030030///cell projection organization+++GO:0022604///regulation of cell morphogenesis","WT1 interacting protein","[WTIP_HUMAN|Reviewed]RecName: Full=Wilms tumor protein 1-interacting protein; Short=WT1-interacting protein;+++[K7EKM1_HUMAN|Unreviewed]SubName: Full=Wilms tumor protein 1-interacting protein {ECO:0000313|Ensembl:ENSP00000465683}; Flags: Fragment;"]
[126526,"'C19orf47'",415.26,356.04,345.68,372.326666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"chromosome 19 open reading frame 47","[CS047_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf47;+++[A0A2R8Y6U9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000495586}; Flags: Fragment;+++[J3QKY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000463294};+++[J3QKZ5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000463305}; Flags: Fragment;+++[J3QS16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000464478}; Flags: Fragment;+++[J3QS80_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000464567}; Flags: Fragment;+++[J9JIE4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000350556}; Flags: Fragment;"]
[126859,"'AXDND1'",1,5,0,2,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"axonemal dynein light chain domain containing 1","[AXDN1_HUMAN|Reviewed]RecName: Full=Axonemal dynein light chain domain-containing protein 1;+++[A6H900_HUMAN|Unreviewed]SubName: Full=Axonemal dynein light chain domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000424373}; SubName: Full=C1orf125 protein {ECO:0000313|EMBL:AAI46824.1};+++[B1AM31_HUMAN|Unreviewed]SubName: Full=Axonemal dynein light chain domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000391716}; Flags: Fragment;+++[D6R9B7_HUMAN|Unreviewed]SubName: Full=Axonemal dynein light chain domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000422992}; Flags: Fragment;+++[D6RDY4_HUMAN|Unreviewed]SubName: Full=Axonemal dynein light chain domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000425198}; Flags: Fragment;+++[D6REE1_HUMAN|Unreviewed]SubName: Full=Axonemal dynein light chain domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000425019}; Flags: Fragment;"]
[127602,"'DNAH14'",67,69.99,65,67.33,"05016///Huntington's disease","H00564///Primary ciliary dyskinesia+++H01282///Spermatogenic failure",null,null,"GO:0005858///axonemal dynein complex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0030286///dynein complex+++GO:0005575///cellular_component+++GO:0042995///cell projection+++GO:0005874///microtubule+++GO:0005929///cilium","GO:0003777///microtubule motor activity+++GO:0003774///motor activity+++GO:0045503///dynein light chain binding+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0005524///ATP binding+++GO:0045505///dynein intermediate chain binding+++GO:0051959///dynein light intermediate chain binding","GO:0060285///cilium-dependent cell motility+++GO:0008150///biological_process+++GO:0007018///microtubule-based movement","dynein axonemal heavy chain 14","[DYH14_HUMAN|Reviewed]RecName: Full=Dynein heavy chain 14, axonemal; AltName: Full=Axonemal beta dynein heavy chain 14; AltName: Full=Ciliary dynein heavy chain 14;+++[A0A1W2PR53_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000492319}; Flags: Fragment;+++[H0YBB1_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000429122}; Flags: Fragment;+++[H0YBI3_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000429568}; Flags: Fragment;+++[H7BXS7_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000328980}; Flags: Fragment;+++[H7C164_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000398678}; Flags: Fragment;+++[H7C374_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000409971}; Flags: Fragment;+++[H7C3Z3_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000414699}; Flags: Fragment;+++[H9KV43_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000332424}; Flags: Fragment;+++[M9MMK7_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 14, axonemal {ECO:0000313|Ensembl:ENSP00000355814}; SubName: Full=HCG22803, isoform CRA_g {ECO:0000313|EMBL:EAW69740.1};+++[Q92866_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain {ECO:0000313|EMBL:AAC50705.1}; Flags: Fragment;"]
[127707,"'KLHDC7A'",121,141,124,128.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:0016567///protein ubiquitination","kelch domain containing 7A","[KLD7A_HUMAN|Reviewed]RecName: Full=Kelch domain-containing protein 7A;+++[A4FU39_HUMAN|Unreviewed]SubName: Full=KLHDC7A protein {ECO:0000313|EMBL:AAI01499.1}; Flags: Fragment;+++[A7E2V3_HUMAN|Unreviewed]SubName: Full=KLHDC7A protein {ECO:0000313|EMBL:AAI51206.1}; Flags: Fragment;"]
[128338,"'DRAM2'",305,207,241,251,null,"H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0001917///photoreceptor inner segment+++GO:0016020///membrane",null,"GO:0007601///visual perception+++GO:0006914///autophagy+++GO:0006915///apoptotic process+++GO:0010506///regulation of autophagy+++GO:0045494///photoreceptor cell maintenance","DNA damage regulated autophagy modulator 2","[DRAM2_HUMAN|Reviewed]RecName: Full=DNA damage-regulated autophagy modulator protein 2; AltName: Full=Transmembrane protein 77;+++[A0A024R0B7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 77, isoform CRA_a {ECO:0000313|EMBL:EAW56467.1};+++[S4R2Z2_HUMAN|Unreviewed]SubName: Full=DNA damage-regulated autophagy modulator protein 2 {ECO:0000313|Ensembl:ENSP00000473779};"]
[128414,"'NKAIN4'",474,396,477,449,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0002028///regulation of sodium ion transport","sodium/potassium transporting ATPase interacting 4","[NKAI4_HUMAN|Reviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 4; AltName: Full=Protein FAM77A;+++[A6NNM2_HUMAN|Unreviewed]SubName: Full=Chromosome 20 open reading frame 58, isoform CRA_a {ECO:0000313|EMBL:EAW75297.1}; SubName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 {ECO:0000313|Ensembl:ENSP00000359330};+++[B3KWY5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ44258 fis, clone TKIDN2019116 {ECO:0000313|EMBL:BAG54297.1};+++[J3JS66_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 {ECO:0000313|Ensembl:ENSP00000359336};+++[J9JIE8_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 {ECO:0000313|Ensembl:ENSP00000359341}; Flags: Fragment;"]
[1289,"'COL5A1'",21086,19701,19303,20030,"04974///Protein digestion and absorption","H00519///Type XI collagenopathies+++H02079///Oto-spondylo-megaepiphyseal dysplasia+++H00802///Ehlers-Danlos syndrome (EDS)+++H02080///Fibrochondrogenesis+++H00605///Deafness, autosomal recessive+++H02072///Stickler syndrome+++H00431///Ossification of the posterior longitudinal ligament of spine (OPLL)+++H00604///Deafness, autosomal dominant+++H00805///Vitreoretinal degeneration+++H02081///Marshall syndrome",null,null,"GO:0031012///extracellular matrix+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005588///collagen type V trimer+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region","GO:0043394///proteoglycan binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0005515///protein binding+++GO:0048407///platelet-derived growth factor binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0046872///metal ion binding","GO:0048592///eye morphogenesis+++GO:1903225///negative regulation of endodermal cell differentiation+++GO:0032964///collagen biosynthetic process+++GO:0043588///skin development+++GO:0097435///supramolecular fiber organization+++GO:0051128///regulation of cellular component organization+++GO:0035989///tendon development+++GO:0016477///cell migration+++GO:0007155///cell adhesion+++GO:0030199///collagen fibril organization+++GO:0003007///heart morphogenesis+++GO:0045112///integrin biosynthetic process+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0001568///blood vessel development+++GO:0030198///extracellular matrix organization","collagen type V alpha 1 chain","[CO5A1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(V) chain; Flags: Precursor;+++[A0A024R8E5_HUMAN|Unreviewed]SubName: Full=Collagen, type V, alpha 1, isoform CRA_a {ECO:0000313|EMBL:EAW88131.1};+++[B2ZZ86_HUMAN|Unreviewed]SubName: Full=Collagen type V alpha 1 {ECO:0000313|EMBL:BAG48312.1};+++[H7BY82_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(V) chain {ECO:0000313|Ensembl:ENSP00000360885}; Flags: Fragment;+++[L8E771_HUMAN|Unreviewed]SubName: Full=Alternative protein COL5A1 {ECO:0000313|EMBL:CCQ42964.1};+++[Q59EE7_HUMAN|Unreviewed]SubName: Full=Pro-alpha-1 type V collagen variant {ECO:0000313|EMBL:BAD93101.1}; Flags: Fragment;+++[Q9UML4_HUMAN|Unreviewed]SubName: Full=Alpha-1 type V collagen {ECO:0000313|EMBL:AAA79853.1}; Flags: Fragment;"]
[1293,"'COL6A3'",1,6,6,4.33333333333333,"05165///Human papillomavirus infection+++04151///PI3K-Akt signaling pathway+++04974///Protein digestion and absorption+++04510///Focal adhesion+++04512///ECM-receptor interaction","H00431///Ossification of the posterior longitudinal ligament of spine (OPLL)+++H01338///Myosclerosis+++H01341///Collagen VI myopathy+++H00590///Congenital muscular dystrophies (CMD/MDC)+++H01340///Bethlem myopathy+++H00831///Primary dystonia+++H01358///Atopic dermatitis+++H01778///Ullrich disease",null,null,"GO:1903561///extracellular vesicle+++GO:0070062///extracellular exosome+++GO:0042383///sarcolemma+++GO:0005788///endoplasmic reticulum lumen+++GO:0005589///collagen type VI trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:0005581///collagen trimer","GO:0030414///peptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030020///extracellular matrix structural constituent conferring tensile strength","GO:0030198///extracellular matrix organization+++GO:0007517///muscle organ development+++GO:0010466///negative regulation of peptidase activity+++GO:0007155///cell adhesion+++GO:0010951///negative regulation of endopeptidase activity+++GO:0003429///growth plate cartilage chondrocyte morphogenesis","collagen type VI alpha 3 chain","[CO6A3_HUMAN|Reviewed]RecName: Full=Collagen alpha-3(VI) chain; Flags: Precursor;+++[B7ZW00_HUMAN|Unreviewed]SubName: Full=COL6A3 protein {ECO:0000313|EMBL:AAI71790.1};+++[C9JNG9_HUMAN|Unreviewed]SubName: Full=Collagen alpha-3(VI) chain {ECO:0000313|Ensembl:ENSP00000389539}; Flags: Fragment;+++[D9ZGF2_HUMAN|Unreviewed]SubName: Full=Collagen, type VI, alpha 3 {ECO:0000313|EMBL:ADL14511.1};+++[E7ENL6_HUMAN|Unreviewed]SubName: Full=Collagen alpha-3(VI) chain {ECO:0000313|Ensembl:ENSP00000315609};+++[I3L392_HUMAN|Unreviewed]SubName: Full=Collagen alpha-3(VI) chain {ECO:0000313|Ensembl:ENSP00000460277}; Flags: Fragment;+++[Q63HQ4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686K04147 {ECO:0000313|EMBL:CAH56139.1}; Flags: Fragment;+++[Q8N4Z1_HUMAN|Unreviewed]SubName: Full=Similar to collagen, type VI, alpha 3 {ECO:0000313|EMBL:AAH33174.1}; Flags: Fragment;"]
[129831,"'RBM45'",95,112,82,96.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0042613///MHC class II protein complex+++GO:1990904///ribonucleoprotein complex","GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0002376///immune system process+++GO:0006955///immune response+++GO:0019882///antigen processing and presentation","RNA binding motif protein 45","[RBM45_HUMAN|Reviewed]RecName: Full=RNA-binding protein 45; AltName: Full=Developmentally-regulated RNA-binding protein 1; Short=RB-1; AltName: Full=RNA-binding motif protein 45;+++[A0A0F6R9J4_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AKE47359.1}; Flags: Fragment;+++[A0A2S0S5B0_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AWA82541.1}; Flags: Fragment;+++[A0A2U9AEQ3_HUMAN|Unreviewed]SubName: Full=MHC class II DR beta chain {ECO:0000313|EMBL:AWO72990.1}; Flags: Fragment;+++[A0A2U9N4R3_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AWT08279.1}; Flags: Fragment;+++[B2ZSE3_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:ACD63076.1}; Flags: Fragment;+++[H7BZE0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 45 {ECO:0000313|Ensembl:ENSP00000389134}; Flags: Fragment;+++[H7C476_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 45 {ECO:0000313|Ensembl:ENSP00000415940}; Flags: Fragment;+++[I7A6V4_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AFN89843.1}; Flags: Fragment;+++[I7ARY2_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AFN89842.1}; Flags: Fragment;+++[O78216_HUMAN|Unreviewed]SubName: Full=Leukocyte antigen class II {ECO:0000313|EMBL:AAC05578.1}; Flags: Fragment;+++[Q29728_HUMAN|Unreviewed]SubName: Full=DRB1 protein {ECO:0000313|EMBL:AAA81369.1}; Flags: Fragment;+++[Q30110_HUMAN|Unreviewed]SubName: Full=MHC DR6V HAG {ECO:0000313|EMBL:AAA36290.1}; Flags: Fragment;+++[Q5XKU0_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAV28303.1};+++[Q6GYF6_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAT46361.1}; Flags: Fragment;+++[Q6J8I8_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAT29062.1}; Flags: Fragment;+++[Q95382_HUMAN|Unreviewed]SubName: Full=MHC class II HLA beta chain {ECO:0000313|EMBL:AAB06950.1}; Flags: Fragment;+++[Q95388_HUMAN|Unreviewed]SubName: Full=HLA class II DRB1 antigen {ECO:0000313|EMBL:AAB17994.1}; Flags: Fragment;+++[Q95462_HUMAN|Unreviewed]SubName: Full=DRB1 protein {ECO:0000313|EMBL:CAA68170.1}; Flags: Fragment;+++[Q9MY22_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAF64297.1}; Flags: Fragment;+++[Q9NPL1_HUMAN|Unreviewed]SubName: Full=Leucocyte antigen DRB1 {ECO:0000313|EMBL:CAB94833.1}; Flags: Fragment;+++[V5NZ06_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AHA93559.1}; Flags: Fragment;"]
[130132,"'RFTN2'",12,2,4,6,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane",null,"GO:0033227///dsRNA transport+++GO:0043330///response to exogenous dsRNA","raftlin family member 2","[RFTN2_HUMAN|Reviewed]RecName: Full=Raftlin-2; AltName: Full=Raft-linking protein 2;+++[C9J6C2_HUMAN|Unreviewed]SubName: Full=Raftlin-2 {ECO:0000313|Ensembl:ENSP00000398128}; Flags: Fragment;+++[H7BZ31_HUMAN|Unreviewed]SubName: Full=Raftlin-2 {ECO:0000313|Ensembl:ENSP00000387459}; Flags: Fragment;"]
[1306,"'COL15A1'",15,29,20,21.3333333333333,"04974///Protein digestion and absorption",{"$nulls":3},"GO:0005788///endoplasmic reticulum lumen+++GO:0005581///collagen trimer+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane+++GO:0005582///collagen type XV trimer+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome","GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0005198///structural molecule activity","GO:0001525///angiogenesis+++GO:0007275///multicellular organism development+++GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0030574///collagen catabolic process","collagen type XV alpha 1 chain","[COFA1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(XV) chain; Contains: RecName: Full=Restin; AltName: Full=Endostatin-XV; AltName: Full=Related to endostatin; AltName: Full=Restin-I; Contains: RecName: Full=Restin-2; AltName: Full=Restin-II; Contains: RecName: Full=Restin-3; AltName: Full=Restin-III; Contains: RecName: Full=Restin-4; AltName: Full=Restin-IV; Flags: Precursor;+++[A0A087X0K0_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XV) chain {ECO:0000313|Ensembl:ENSP00000483455};+++[B3KTP7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38566 fis, clone HCHON2005118, highly similar to Collagen alpha-1(XV) chain {ECO:0000313|EMBL:BAG53159.1};"]
[1310,"'COL19A1'",36,24,19,26.3333333333333,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005581///collagen trimer+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0031012///extracellular matrix","GO:0005201///extracellular matrix structural constituent+++GO:0030674///protein binding, bridging","GO:0001501///skeletal system development+++GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0030154///cell differentiation+++GO:0098609///cell-cell adhesion+++GO:0030574///collagen catabolic process+++GO:0007275///multicellular organism development+++GO:0007517///muscle organ development+++GO:0007519///skeletal muscle tissue development","collagen type XIX alpha 1 chain","[COJA1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(XIX) chain; AltName: Full=Collagen alpha-1(Y) chain; Flags: Precursor;+++[A0A087WVJ7_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XIX) chain {ECO:0000313|Ensembl:ENSP00000479481};+++[Q5JVU1_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XIX) chain {ECO:0000313|Ensembl:ENSP00000416556}; Flags: Fragment;"]
[131544,"'CRYBG3'",226,287,225,246,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00527///Retinitis pigmentosa (RP)+++H00418///Bardet-Biedl syndrome (BBS)",null,null,"GO:0032991///protein-containing complex","GO:0030246///carbohydrate binding+++GO:0051018///protein kinase A binding","GO:0008150///biological_process","crystallin beta-gamma domain containing 3","[CRBG3_HUMAN|Reviewed]RecName: Full=Very large A-kinase anchor protein; Short=vlAKAP; AltName: Full=Beta/gamma crystallin domain-containing protein 3;+++[C9J659_HUMAN|Unreviewed]SubName: Full=Very large A-kinase anchor protein {ECO:0000313|Ensembl:ENSP00000418420}; Flags: Fragment;"]
[132014,"'IL17RE'",290,313,279,294,"04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0016020///membrane","GO:0030368///interleukin-17 receptor activity+++GO:0005515///protein binding","GO:0006954///inflammatory response+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:0019221///cytokine-mediated signaling pathway","interleukin 17 receptor E","[I17RE_HUMAN|Reviewed]RecName: Full=Interleukin-17 receptor E; Short=IL-17 receptor E; Short=IL-17RE; Flags: Precursor;+++[A6NL85_HUMAN|Unreviewed]SubName: Full=Interleukin-17 receptor E {ECO:0000313|Ensembl:ENSP00000406076}; SubName: Full=cDNA FLJ57755, highly similar to Homo sapiens interleukin 17 receptor E (IL17RE), transcript variant 5, mRNA {ECO:0000313|EMBL:BAG60327.1};+++[B4DMZ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56993, highly similar to Homo sapiens interleukin 17 receptor E (IL17RE), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG60055.1};+++[C9J1R2_HUMAN|Unreviewed]SubName: Full=Interleukin-17 receptor E {ECO:0000313|Ensembl:ENSP00000400768}; Flags: Fragment;+++[F8WB54_HUMAN|Unreviewed]SubName: Full=Interleukin-17 receptor E {ECO:0000313|Ensembl:ENSP00000373326};+++[F8WCU7_HUMAN|Unreviewed]SubName: Full=Interleukin-17 receptor E {ECO:0000313|Ensembl:ENSP00000415701};+++[J3KQN7_HUMAN|Unreviewed]SubName: Full=Interleukin 17 receptor E, isoform CRA_c {ECO:0000313|EMBL:EAW64018.1}; SubName: Full=Interleukin-17 receptor E {ECO:0000313|Ensembl:ENSP00000404916};+++[L0R6I5_HUMAN|Unreviewed]SubName: Full=Alternative protein IL17RE {ECO:0000313|EMBL:CCO13747.1};+++[L8E985_HUMAN|Unreviewed]SubName: Full=Alternative protein IL17RE {ECO:0000313|EMBL:CCQ43880.1};"]
[132720,"'FAM241A'",48,43,39,43.3333333333333,"00380///Tryptophan metabolism+++01100///Metabolic pathways+++04137///Mitophagy - animal+++04140///Autophagy - animal",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin+++R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate","GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus","GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","family with sequence similarity 241 member A","[F241A_HUMAN|Reviewed]RecName: Full=Uncharacterized protein FAM241A;"]
[133491,"'C5orf47'",1,2,0,1,{"$nulls":7},"chromosome 5 open reading frame 47","[CE047_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf47;"]
[134147,"'CMBL'",276,283,321.66,293.553333333333,"01110///Biosynthesis of secondary metabolites+++00361///Chlorocyclohexane and chlorobenzene degradation+++01120///Microbial metabolism in diverse environments+++00623///Toluene degradation+++01100///Metabolic pathways+++00364///Fluorobenzoate degradation+++01130///Biosynthesis of antibiotics",null,null,"R03893///4-Carboxymethylenebut-2-en-4-olide lactonohydrolase   cis-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate+++R09220///dienelactone hydrolase   3-Chloro-2-methyldienelactone + H2O <=> 3-Chloro-2-methylmaleylacetate+++R08121///4-fluoromuconolactone lactonohydrolase   4-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid+++R08120///5-fluoromuconolactone lactonohydrolase   5-Fluoromuconolactone + H2O <=> 2-Maleylacetate + Hydrofluoric acid+++R06838///4-carboxymethylenebut-2-en-4-olide lactonohydrolase   trans-4-Carboxymethylenebut-2-en-4-olide + H2O <=> 2-Maleylacetate+++R05511///cis-2-Chloro-4-carboxymethylenebut-2-en-1,4-olide + H2O <=> 2-Chloromaleylacetate+++R09136///2,3,5-trichlorodienelactone lactonohydrolase   2,3,5-Trichlorodienelactone + H2O <=> 2,3,5-Trichloromaleylacetate+++R05510///Protoanemonin lactonohydrolase   Protoanemonin + H2O <=> cis-Acetylacrylate+++R09222///dienelactone hydrolase   2-Chloro-5-methyl-cis-dienelactone + H2O <=> 2-Chloro-5-methylmaleylacetate+++R06835///4-carboxymethylenebut-2-en-4-olide lactonohydrolase   2,5-Dichloro-carboxymethylenebut-2-en-4-olide + H2O <=> 2,5-Dichloro-4-oxohex-2-enedioate","GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0016787///hydrolase activity","GO:0006805///xenobiotic metabolic process","carboxymethylenebutenolidase homolog","[CMBL_HUMAN|Reviewed]RecName: Full=Carboxymethylenebutenolidase homolog; EC=3.1.-.-;"]
[1347,"'COX7A2'",522,499,522,514.333333333333,"05010///Alzheimer's disease+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease (NAFLD)+++00190///Oxidative phosphorylation+++05016///Huntington's disease+++05012///Parkinson's disease+++04260///Cardiac muscle contraction",null,"M00154///Cytochrome c oxidase",null,"GO:0016021///integral component of membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0097249///mitochondrial respiratory chain supercomplex","GO:0009055///electron transfer activity+++GO:0004129///cytochrome-c oxidase activity","GO:0002082///regulation of oxidative phosphorylation+++GO:1902600///proton transmembrane transport+++GO:0022900///electron transport chain+++GO:0097250///mitochondrial respiratory chain supercomplex assembly","cytochrome c oxidase subunit 7A2","[CX7A2_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial; AltName: Full=Cytochrome c oxidase subunit VIIa-liver/heart; Short=Cytochrome c oxidase subunit VIIa-L; Short=Cytochrome c oxidase subunit VIIaL; Flags: Precursor;+++[D6R9C3_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial {ECO:0000313|Ensembl:ENSP00000422979};+++[D6RA35_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial {ECO:0000313|Ensembl:ENSP00000423432};+++[D6RGV5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial {ECO:0000313|Ensembl:ENSP00000421193}; Flags: Fragment;+++[D6RIE3_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial {ECO:0000313|Ensembl:ENSP00000425951};+++[H0UI06_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial {ECO:0000313|Ensembl:ENSP00000359098}; SubName: Full=Cytochrome c oxidase subunit VIIa polypeptide 2 (Liver), isoform CRA_a {ECO:0000313|EMBL:EAW48747.1};+++[H0Y8S6_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase subunit 7A2, mitochondrial {ECO:0000313|Ensembl:ENSP00000421969}; Flags: Fragment;+++[Q496I0_HUMAN|Unreviewed]SubName: Full=COX7A2 protein {ECO:0000313|EMBL:AAI33655.1}; SubName: Full=Cytochrome c oxidase subunit VIIa polypeptide 2 (Liver) {ECO:0000313|EMBL:AAI00854.1};"]
[135228,"'CD109'",184,203,178,188.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0031092///platelet alpha granule membrane+++GO:0031225///anchored component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane","GO:0050431///transforming growth factor beta binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010839///negative regulation of keratinocyte proliferation+++GO:0001942///hair follicle development+++GO:0072675///osteoclast fusion+++GO:0010466///negative regulation of peptidase activity+++GO:0002576///platelet degranulation+++GO:0045616///regulation of keratinocyte differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0001933///negative regulation of protein phosphorylation+++GO:0061045///negative regulation of wound healing+++GO:0010951///negative regulation of endopeptidase activity","CD109 molecule","[CD109_HUMAN|Reviewed]RecName: Full=CD109 antigen; AltName: Full=150 kDa TGF-beta-1-binding protein; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; AltName: Full=Platelet-specific Gov antigen; AltName: Full=p180; AltName: Full=r150; AltName: CD_antigen=CD109; Flags: Precursor;+++[F1C639_HUMAN|Unreviewed]SubName: Full=CD109 antigen {ECO:0000313|EMBL:ADZ28543.1}; Flags: Fragment;"]
[1361,"'CPB2'",0,1,0,0.333333333333333,"04974///Protein digestion and absorption+++04972///Pancreatic secretion+++04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005623///cell+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0004180///carboxypeptidase activity+++GO:0008233///peptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0042493///response to drug+++GO:0009408///response to heat+++GO:0097421///liver regeneration+++GO:0006508///proteolysis+++GO:0010757///negative regulation of plasminogen activation+++GO:0030449///regulation of complement activation+++GO:0071333///cellular response to glucose stimulus+++GO:0007596///blood coagulation+++GO:0003331///positive regulation of extracellular matrix constituent secretion+++GO:0042730///fibrinolysis+++GO:2000346///negative regulation of hepatocyte proliferation+++GO:0007599///hemostasis+++GO:0051918///negative regulation of fibrinolysis","carboxypeptidase B2","[CBPB2_HUMAN|Reviewed]RecName: Full=Carboxypeptidase B2; EC=3.4.17.20 {ECO:0000269|PubMed:10574983}; AltName: Full=Carboxypeptidase U; Short=CPU; AltName: Full=Plasma carboxypeptidase B; Short=pCPB; AltName: Full=Thrombin-activable fibrinolysis inhibitor; Short=TAFI; Flags: Precursor;+++[A0A087WSY5_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase B2 {ECO:0000313|Ensembl:ENSP00000400714};"]
[1368,"'CPM'",181,215.99,192,196.33,"05218///Melanoma+++04140///Autophagy - animal+++04625///C-type lectin receptor signaling pathway+++05206///MicroRNAs in cancer+++00380///Tryptophan metabolism+++05220///Chronic myeloid leukemia+++05215///Prostate cancer+++04218///Cellular senescence+++05163///Human cytomegalovirus infection+++04144///Endocytosis+++05214///Glioma+++05205///Proteoglycans in cancer+++04137///Mitophagy - animal+++05202///Transcriptional misregulation in cancer+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++04120///Ubiquitin mediated proteolysis+++04919///Thyroid hormone signaling pathway+++04068///FoxO signaling pathway+++04110///Cell cycle+++04115///p53 signaling pathway+++05219///Bladder cancer+++04151///PI3K-Akt signaling pathway+++05200///Pathways in cancer+++01524///Platinum drug resistance+++05203///Viral carcinogenesis+++01100///Metabolic pathways+++01522///Endocrine resistance","H00025///Penile cancer+++H00037///Alveolar rhabdomyosarcoma+++H00036///Osteosarcoma+++H00042///Glioma+++H01667///Medulloblastoma+++H01513///Retinoblastoma+++H00028///Choriocarcinoma","M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0031225///anchored component of membrane","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding","GO:0016485///protein processing+++GO:0006508///proteolysis+++GO:0009653///anatomical structure morphogenesis+++GO:0006518///peptide metabolic process","carboxypeptidase M","[CBPM_HUMAN|Reviewed]RecName: Full=Carboxypeptidase M; Short=CPM; EC=3.4.17.12 {ECO:0000269|PubMed:12457462}; Flags: Precursor;+++[F8VR29_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase M {ECO:0000313|Ensembl:ENSP00000450400};+++[F8VU13_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase M {ECO:0000313|Ensembl:ENSP00000448078}; Flags: Fragment;+++[F8VVI6_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase M {ECO:0000313|Ensembl:ENSP00000449911}; Flags: Fragment;+++[F8W111_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase M {ECO:0000313|Ensembl:ENSP00000446799}; Flags: Fragment;+++[H0YHG6_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase M {ECO:0000313|Ensembl:ENSP00000447051}; Flags: Fragment;+++[H0YHN7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase M {ECO:0000313|Ensembl:ENSP00000447455}; Flags: Fragment;"]
[137695,"'TMEM68'",133,86,118,112.333333333333,"03013///RNA transport+++04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016746///transferase activity, transferring acyl groups","GO:0008152///metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000387///spliceosomal snRNP assembly+++GO:0019216///regulation of lipid metabolic process+++GO:0009452///7-methylguanosine RNA capping+++GO:0022613///ribonucleoprotein complex biogenesis+++GO:0006351///transcription, DNA-templated+++GO:0036261///7-methylguanosine cap hypermethylation","transmembrane protein 68","[TMM68_HUMAN|Reviewed]RecName: Full=Transmembrane protein 68;+++[A0A024R7Y2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68, isoform CRA_a {ECO:0000313|EMBL:EAW86759.1};+++[E5RGT2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000428688};+++[E5RHI6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429758}; Flags: Fragment;+++[E5RHU1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429667}; Flags: Fragment;+++[E5RHZ2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000430838}; Flags: Fragment;+++[E5RJ96_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429175}; Flags: Fragment;+++[E5RJI9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000430542}; Flags: Fragment;+++[E5RJN2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429026};+++[H0YAX4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000428236}; Flags: Fragment;+++[H0YAY9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000428318}; Flags: Fragment;+++[H0YC64_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000431018}; Flags: Fragment;+++[Q49A68_HUMAN|Unreviewed]SubName: Full=TMEM68 protein {ECO:0000313|EMBL:AAH43417.1}; SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000481143};"]
[138311,"'FAM69B'",855,950,768,857.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0005515///protein binding",null,"family with sequence similarity 69 member B","[FA69B_HUMAN|Reviewed]RecName: Full=Protein FAM69B;+++[A0A024R8I5_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 69, member B, isoform CRA_a {ECO:0000313|EMBL:EAW88254.1};"]
[138716,"'RPP25L'",156,157,156,156.333333333333,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003723///RNA binding",null,"ribonuclease P/MRP subunit p25 like","[RP25L_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p25-like protein; Short=RNase P protein subunit-like p25; AltName: Full=Rpp25-like protein;"]
[1390,"'CREM'",189,194,177,186.666666666667,"05166///HTLV-I infection+++04261///Adrenergic signaling in cardiomyocytes",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005667///transcription factor complex+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0008140///cAMP response element binding protein binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0006631///fatty acid metabolic process+++GO:0042752///regulation of circadian rhythm+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006687///glycosphingolipid metabolic process+++GO:0048511///rhythmic process+++GO:0007275///multicellular organism development+++GO:0006006///glucose metabolic process+++GO:0007165///signal transduction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0007283///spermatogenesis","cAMP responsive element modulator","[CREM_HUMAN|Reviewed]RecName: Full=cAMP-responsive element modulator {ECO:0000305}; AltName: Full=Inducible cAMP early repressor; Short=ICER;+++[A0A0A0MSU8_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000403938}; Flags: Fragment;+++[C9IYM9_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000418798}; Flags: Fragment;+++[C9J2J0_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000417399}; Flags: Fragment;+++[C9J5A7_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000417130}; Flags: Fragment;+++[C9K092_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000419684}; Flags: Fragment;+++[E9PAR2_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000344365};+++[E9PB41_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000419018};+++[F8WB03_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000417058};+++[F8WDF2_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000420453};+++[G5E998_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000363853};+++[H7C4X0_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000418450}; Flags: Fragment;+++[J3KQC0_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000393538};+++[J3KR46_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000417165};+++[Q9BYY5_HUMAN|Unreviewed]SubName: Full=cAMP responsive element moderator {ECO:0000313|EMBL:AAG47575.1}; Flags: Fragment;+++[R4GN75_HUMAN|Unreviewed]SubName: Full=cAMP-responsive element modulator {ECO:0000313|Ensembl:ENSP00000473519};"]
[139886,"'SPIN4'",30,25,26,27,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0035064///methylated histone binding+++GO:0005515///protein binding","GO:0007276///gamete generation","spindlin family member 4","[SPIN4_HUMAN|Reviewed]RecName: Full=Spindlin-4;+++[X6R8Y7_HUMAN|Unreviewed]SubName: Full=Spindlin-4 {ECO:0000313|Ensembl:ENSP00000364018};"]
[140545,"'RNF32'",19,17,18,18,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005768///endosome+++GO:0016235///aggresome+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0042733///embryonic digit morphogenesis","ring finger protein 32","[RNF32_HUMAN|Reviewed]RecName: Full=RING finger protein 32;+++[A0A024RD87_HUMAN|Unreviewed]SubName: Full=Ring finger protein 32, isoform CRA_b {ECO:0000313|EMBL:EAX04555.1};+++[C9JXI4_HUMAN|Unreviewed]SubName: Full=RING finger protein 32 {ECO:0000313|Ensembl:ENSP00000388088}; Flags: Fragment;+++[E9PES2_HUMAN|Unreviewed]SubName: Full=RING finger protein 32 {ECO:0000313|Ensembl:ENSP00000385815}; Flags: Fragment;+++[G5E940_HUMAN|Unreviewed]SubName: Full=RING finger protein 32 {ECO:0000313|Ensembl:ENSP00000308894}; SubName: Full=Ring finger protein 32, isoform CRA_a {ECO:0000313|EMBL:EAX04551.1};+++[Q8TAF1_HUMAN|Unreviewed]SubName: Full=Ring finger protein RNF32 {ECO:0000313|EMBL:AAM18668.1}; Flags: Fragment;+++[Q8TDF9_HUMAN|Unreviewed]SubName: Full=Ring finger protein RNF32 {ECO:0000313|EMBL:AAM18667.1}; Flags: Fragment;"]
[140612,"'ZFP28'",125.52,155.01,177,152.51,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","ZFP28 zinc finger protein","[ZFP28_HUMAN|Reviewed]RecName: Full=Zinc finger protein 28 homolog; Short=Zfp-28; AltName: Full=Krueppel-like zinc finger factor X6;+++[A0JNV5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 28 homolog (Mouse) {ECO:0000313|EMBL:AAI27003.1};+++[K7EL00_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 28 homolog {ECO:0000313|Ensembl:ENSP00000465853}; Flags: Fragment;+++[Q9UQD2_HUMAN|Unreviewed]SubName: Full=R31665_2 [AA 1-673 ] {ECO:0000313|EMBL:AAD23606.1}; SubName: Full=Zinc finger protein 28 homolog (Mouse), isoform CRA_b {ECO:0000313|EMBL:EAW72464.1};"]
[140803,"'TRPM6'",33,18,34,28.3333333333333,"04978///Mineral absorption","H01210///Hypomagnesemia",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0016020///membrane","GO:0005262///calcium channel activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005216///ion channel activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0005261///cation channel activity","GO:0006812///cation transport+++GO:0006816///calcium ion transport+++GO:0006468///protein phosphorylation+++GO:0006811///ion transport+++GO:0098655///cation transmembrane transport+++GO:0009636///response to toxic substance+++GO:0034220///ion transmembrane transport+++GO:0030001///metal ion transport+++GO:0051262///protein tetramerization+++GO:0070588///calcium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0016310///phosphorylation","transient receptor potential cation channel subfamily M member 6","[TRPM6_HUMAN|Reviewed]RecName: Full=Transient receptor potential cation channel subfamily M member 6; EC=2.7.11.1; AltName: Full=Channel kinase 2; AltName: Full=Melastatin-related TRP cation channel 6;+++[Q96LV9_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily M member 6 {ECO:0000313|Ensembl:ENSP00000351942}; SubName: Full=Transient receptor potential cation channel, subfamily M, member 6, isoform CRA_j {ECO:0000313|EMBL:EAW62562.1}; SubName: Full=cDNA FLJ25019 fis, clone CBL01642 {ECO:0000313|EMBL:BAB71558.1};"]
[140883,"'ZNF280B'",98,110,113,107,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 280B","[Z280B_HUMAN|Reviewed]RecName: Full=Zinc finger protein 280B; AltName: Full=5'OY11.1; AltName: Full=Suppressor of hairy wing homolog 2; AltName: Full=Zinc finger protein 279; AltName: Full=Zinc finger protein 632;+++[A0A0D9SEJ8_HUMAN|Unreviewed]SubName: Full=Suppressor of hairy wing homolog 2 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW59516.1}; SubName: Full=Zinc finger protein 280B {ECO:0000313|Ensembl:ENSP00000485750};+++[B3KUN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40289 fis, clone TESTI2028151, highly similar to Suppressor of hairy wing homolog 2 (Zinc finger protein 632) {ECO:0000313|EMBL:BAG53494.1};"]
[1428,"'CRYM'",7,12,6,8.33333333333333,{"$nulls":4},"GO:0005782///peroxisomal matrix+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016491///oxidoreductase activity+++GO:0047127///thiomorpholine-carboxylate dehydrogenase activity+++GO:0003714///transcription corepressor activity+++GO:0016639///oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor+++GO:0050661///NADP binding+++GO:0070324///thyroid hormone binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0042562///hormone binding","GO:0070327///thyroid hormone transport+++GO:0006554///lysine catabolic process+++GO:0055114///oxidation-reduction process+++GO:0042403///thyroid hormone metabolic process+++GO:0007605///sensory perception of sound+++GO:0000122///negative regulation of transcription by RNA polymerase II","crystallin mu","[CRYM_HUMAN|Reviewed]RecName: Full=Ketimine reductase mu-crystallin; EC=1.5.1.25; AltName: Full=NADP-regulated thyroid-hormone-binding protein;+++[I3L2W5_HUMAN|Unreviewed]SubName: Full=Ketimine reductase mu-crystallin {ECO:0000313|Ensembl:ENSP00000459982};+++[I3L325_HUMAN|Unreviewed]SubName: Full=Ketimine reductase mu-crystallin {ECO:0000313|Ensembl:ENSP00000460126}; Flags: Fragment;+++[I3L3J9_HUMAN|Unreviewed]SubName: Full=Ketimine reductase mu-crystallin {ECO:0000313|Ensembl:ENSP00000460510}; Flags: Fragment;+++[I3L3Y1_HUMAN|Unreviewed]SubName: Full=Ketimine reductase mu-crystallin {ECO:0000313|Ensembl:ENSP00000460820}; Flags: Fragment;+++[I3NI53_HUMAN|Unreviewed]SubName: Full=Ketimine reductase mu-crystallin {ECO:0000313|Ensembl:ENSP00000461904}; Flags: Fragment;"]
[143384,"'CACUL1'",724,572,623,639.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031461///cullin-RING ubiquitin ligase complex","GO:0019901///protein kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0045860///positive regulation of protein kinase activity+++GO:0008284///positive regulation of cell proliferation+++GO:0006511///ubiquitin-dependent protein catabolic process","CDK2 associated cullin domain 1","[CACL1_HUMAN|Reviewed]RecName: Full=CDK2-associated and cullin domain-containing protein 1; AltName: Full=Cdk-associated cullin1;"]
[143686,"'SESN3'",2322,2438,2350,2370,"04115///p53 signaling pathway+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0061700///GATOR2 complex+++GO:0031932///TORC2 complex+++GO:0005737///cytoplasm","GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0070728///leucine binding","GO:0038203///TORC2 signaling+++GO:1901031///regulation of response to reactive oxygen species+++GO:1904262///negative regulation of TORC1 signaling+++GO:0055114///oxidation-reduction process+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:0071230///cellular response to amino acid stimulus+++GO:1990253///cellular response to leucine starvation+++GO:0042593///glucose homeostasis+++GO:0016239///positive regulation of macroautophagy+++GO:0034198///cellular response to amino acid starvation+++GO:0032868///response to insulin+++GO:0042149///cellular response to glucose starvation+++GO:0051896///regulation of protein kinase B signaling+++GO:0071233///cellular response to leucine","sestrin 3","[SESN3_HUMAN|Reviewed]RecName: Full=Sestrin-3 {ECO:0000305};+++[A0A0U1RR17_HUMAN|Unreviewed]SubName: Full=Sestrin-3 {ECO:0000313|Ensembl:ENSP00000489281}; Flags: Fragment;+++[F5H1K7_HUMAN|Unreviewed]SubName: Full=Sestrin-3 {ECO:0000313|Ensembl:ENSP00000439580}; Flags: Fragment;"]
[144348,"'ZNF664'",2758.76,2831.79,2532.75,2707.76666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0008150///biological_process+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 664","[ZN664_HUMAN|Reviewed]RecName: Full=Zinc finger protein 664; AltName: Full=Zinc finger protein 176 {ECO:0000312|HGNC:HGNC:25406}; AltName: Full=Zinc finger protein from organ of Corti;+++[A0A024RBR7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 664, isoform CRA_a {ECO:0000313|EMBL:EAW98446.1};+++[A0A024RBR8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 664, isoform CRA_b {ECO:0000313|EMBL:EAW98443.1};+++[Q0P6D9_HUMAN|Unreviewed]SubName: Full=ZNF664 protein {ECO:0000313|EMBL:AAH17960.1};"]
[144568,"'A2ML1'",0,3,0,1,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0030414///peptidase inhibitor activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity","GO:0052548///regulation of endopeptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010466///negative regulation of peptidase activity","alpha-2-macroglobulin like 1","[A2ML1_HUMAN|Reviewed]RecName: Full=Alpha-2-macroglobulin-like protein 1; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9; Flags: Precursor;+++[B3KVV6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1 (A2ML1), mRNA {ECO:0000313|EMBL:BAG53918.1};+++[F5GXP1_HUMAN|Unreviewed]SubName: Full=Alpha-2-macroglobulin-like protein 1 {ECO:0000313|Ensembl:ENSP00000440057}; Flags: Fragment;+++[F5GYG7_HUMAN|Unreviewed]SubName: Full=Alpha-2-macroglobulin-like protein 1 {ECO:0000313|Ensembl:ENSP00000440662}; Flags: Fragment;+++[H0YGG5_HUMAN|Unreviewed]SubName: Full=Alpha-2-macroglobulin-like protein 1 {ECO:0000313|Ensembl:ENSP00000443174}; Flags: Fragment;+++[H0YH14_HUMAN|Unreviewed]SubName: Full=Alpha-2-macroglobulin-like protein 1 {ECO:0000313|Ensembl:ENSP00000445674}; Flags: Fragment;"]
[145407,"'ARMH4'",2877,3065,2574.07,2838.69,"00380///Tryptophan metabolism+++01100///Metabolic pathways",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin","GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","armadillo-like helical domain containing 4","[ARMD4_HUMAN|Reviewed]RecName: Full=Armadillo-like helical domain-containing protein 4 {ECO:0000305}; Flags: Precursor;+++[A0A087WT98_HUMAN|Unreviewed]SubName: Full=Armadillo-like helical domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000477692}; Flags: Fragment;+++[B2RUU6_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 37 {ECO:0000313|EMBL:AAI46862.1};"]
[145447,"'ABHD12B'",0,2,0,0.666666666666667,"04922///Glucagon signaling pathway+++04140///Autophagy - animal+++02026///Biofilm formation - Escherichia coli+++01100///Metabolic pathways+++04910///Insulin signaling pathway+++04217///Necroptosis+++04931///Insulin resistance+++01110///Biosynthesis of secondary metabolites+++04137///Mitophagy - animal+++00500///Starch and sucrose metabolism","H01944///Glycogen storage disease type VI+++H01760///Hepatic glycogen storage disease+++H00992///Seckel syndrome+++H01762///Muscle glycogen storage disease+++H01943///Glycogen storage disease type V+++H00069///Glycogen storage diseases (GSD)",null,"R02111///1,4-alpha-D-Glucan:orthophosphate alpha-D-glucosyltransferase Starch + Orthophosphate <=> Amylose + D-Glucose 1-phosphate","GO:0005813///centrosome+++GO:0036449///microtubule minus-end+++GO:0005634///nucleus+++GO:0034774///secretory granule lumen+++GO:0072686///mitotic spindle+++GO:0120103///centriolar subdistal appendage+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0000242///pericentriolar material+++GO:0097431///mitotic spindle pole+++GO:0070062///extracellular exosome+++GO:1904813///ficolin-1-rich granule lumen+++GO:0097539///ciliary transition fiber+++GO:0005814///centriole+++GO:0005730///nucleolus+++GO:0000922///spindle pole+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity","GO:0005977///glycogen metabolic process+++GO:0042593///glucose homeostasis+++GO:0008104///protein localization+++GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0090222///centrosome-templated microtubule nucleation+++GO:0051642///centrosome localization+++GO:0070266///necroptotic process+++GO:0043312///neutrophil degranulation+++GO:0005980///glycogen catabolic process+++GO:0009617///response to bacterium+++GO:0034454///microtubule anchoring at centrosome+++GO:0010457///centriole-centriole cohesion","abhydrolase domain containing 12B","[AB12B_HUMAN|Reviewed]RecName: Full=Protein ABHD12B {ECO:0000305}; EC=3.-.-.-; AltName: Full=Abhydrolase domain-containing protein 12B {ECO:0000312|HGNC:HGNC:19837}; AltName: Full=Alpha/beta hydrolase domain-containing protein 12B {ECO:0000305};"]
[146198,"'ZFP90'",587,642,547,592,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0043392///negative regulation of DNA binding+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","ZFP90 zinc finger protein","[ZFP90_HUMAN|Reviewed]RecName: Full=Zinc finger protein 90 homolog; Short=Zfp-90; AltName: Full=Zinc finger protein 756;+++[H3BMI1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000454391};+++[H3BVC6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000458051}; Flags: Fragment;+++[I3L0T2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000458323}; Flags: Fragment;+++[I3L0X7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000458410}; Flags: Fragment;+++[I3L1L4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000458920}; Flags: Fragment;+++[I3L2Q3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000459846}; Flags: Fragment;+++[I3L3M0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000460560}; Flags: Fragment;+++[J3QKQ8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 90 homolog {ECO:0000313|Ensembl:ENSP00000463193};"]
[146212,"'KCTD19'",1,3,0,1.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":5},"GO:0051260///protein homooligomerization","potassium channel tetramerization domain containing 19","[KCD19_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein KCTD19;+++[H3BVC0_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein KCTD19 {ECO:0000313|Ensembl:ENSP00000458045}; Flags: Fragment;+++[J3KRQ9_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein KCTD19 {ECO:0000313|Ensembl:ENSP00000462122};+++[J3KSZ9_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein KCTD19 {ECO:0000313|Ensembl:ENSP00000462732}; Flags: Fragment;+++[J3QKV2_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein KCTD19 {ECO:0000313|Ensembl:ENSP00000463249}; Flags: Fragment;"]
[146540,"'ZNF785'",255,276,221.31,250.77,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 785","[ZN785_HUMAN|Reviewed]RecName: Full=Zinc finger protein 785;+++[A0A024QZC7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW52232.1};+++[H3BR67_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 785 {ECO:0000313|Ensembl:ENSP00000456097}; Flags: Fragment;+++[I3L119_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 785 {ECO:0000313|Ensembl:ENSP00000458511}; Flags: Fragment;"]
[146853,"'C17orf50'",0,0,1,0.333333333333333,{"$nulls":7},"chromosome 17 open reading frame 50","[CQ050_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf50;+++[A0A075B7C2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf50 {ECO:0000313|Ensembl:ENSP00000474048};+++[A0A075B7E2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf50 {ECO:0000313|Ensembl:ENSP00000474618};"]
[147179,"'WIPF2'",1277,1242.32,1307.03,1275.45,"04144///Endocytosis","H01523///Wiskott-Aldrich syndrome",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005884///actin filament+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030479///actin cortical patch","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0000147///actin cortical patch assembly+++GO:0051127///positive regulation of actin nucleation+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030048///actin filament-based movement+++GO:0006897///endocytosis+++GO:0051666///actin cortical patch localization","WAS/WASL interacting protein family member 2","[WIPF2_HUMAN|Reviewed]RecName: Full=WAS/WASL-interacting protein family member 2; AltName: Full=WASP-interacting protein-related protein; AltName: Full=WIP- and CR16-homologous protein; AltName: Full=WIP-related protein;+++[A0A024R1X2_HUMAN|Unreviewed]SubName: Full=WIRE protein, isoform CRA_a {ECO:0000313|EMBL:EAW60649.1};+++[A8MWR2_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000377663}; SubName: Full=cDNA FLJ30495 fis, clone BRAWH2000323, moderately similar to WIP-related protein {ECO:0000313|EMBL:BAG51456.1};+++[J3KSA3_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000462386}; Flags: Fragment;+++[J3QKM5_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000463149}; Flags: Fragment;+++[J3QQS0_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000463869};"]
[147670,"'SMIM17'",4.94,5.13,4.99,5.02,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"small integral membrane protein 17","[SIM17_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 17;+++[M0R1N7_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 17 {ECO:0000313|Ensembl:ENSP00000472019};"]
[147837,"'ZNF563'",10,16,12,12.6666666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 563","[ZN563_HUMAN|Reviewed]RecName: Full=Zinc finger protein 563;+++[A0A0C4DGQ9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 563 {ECO:0000313|Ensembl:ENSP00000469879};+++[M0R1L6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 563 {ECO:0000313|Ensembl:ENSP00000471960}; Flags: Fragment;+++[M0R1Q6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 563 {ECO:0000313|Ensembl:ENSP00000472052}; Flags: Fragment;"]
[148113,"'CILP2'",95,113,142,116.666666666667,"05010///Alzheimer's disease+++04723///Retrograde endocannabinoid signaling+++05016///Huntington's disease+++04714///Thermogenesis+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00146///NADH dehydrogenase (ubiquinone) 1 alpha subcomplex",null,"GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0004035///alkaline phosphatase activity+++GO:0004551///nucleotide diphosphatase activity","GO:0016311///dephosphorylation","cartilage intermediate layer protein 2","[CILP2_HUMAN|Reviewed]RecName: Full=Cartilage intermediate layer protein 2; Short=CILP-2; Contains: RecName: Full=Cartilage intermediate layer protein 2 C1; Contains: RecName: Full=Cartilage intermediate layer protein 2 C2; Flags: Precursor;+++[K7EPJ4_HUMAN|Unreviewed]SubName: Full=Cartilage intermediate layer protein 2, isoform CRA_b {ECO:0000313|EMBL:EAW84833.1};"]
[148304,"'C1orf74'",55,42,38,45,{"$nulls":7},"chromosome 1 open reading frame 74","[CA074_HUMAN|Reviewed]RecName: Full=UPF0739 protein C1orf74;+++[A0A0A8K8E6_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 74 {ECO:0000313|EMBL:EAW93440.1}; SubName: Full=Up-regulated in lung cancer 4 {ECO:0000313|EMBL:BAQ19750.1};"]
[148808,"'MFSD4A'",30.61,30.14,38,32.9166666666667,"04010///MAPK signaling pathway+++05202///Transcriptional misregulation in cancer+++05166///HTLV-I infection","H00024///Prostate cancer",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005355///glucose transmembrane transporter activity","GO:1904659///glucose transmembrane transport+++GO:0055085///transmembrane transport","major facilitator superfamily domain containing 4A","[MFD4A_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 4A; AltName: Full=Major facilitator superfamily domain-containing protein 4;+++[A0A024R9D6_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain containing 4, isoform CRA_a {ECO:0000313|EMBL:EAW91565.1};+++[A0A087WUK7_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000478732};+++[A0A087WWW5_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000480554}; Flags: Fragment;+++[A0A087WYZ8_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000482239};+++[A0A087X0S2_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000483626}; Flags: Fragment;+++[B7Z2V5_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain containing 4, isoform CRA_c {ECO:0000313|EMBL:EAW91567.1}; SubName: Full=cDNA FLJ52542 {ECO:0000313|EMBL:BAH11991.1};+++[B7Z8X0_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000440183}; SubName: Full=cDNA FLJ56203 {ECO:0000313|EMBL:BAH14106.1};+++[F5H391_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000445329};+++[Q96KX6_HUMAN|Unreviewed]SubName: Full=MFSD4 protein {ECO:0000313|EMBL:AAH16377.1}; Flags: Fragment;"]
[149428,"'BNIPL'",1,0,2,1,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0004309///exopolyphosphatase activity+++GO:0042802///identical protein binding","GO:0006915///apoptotic process+++GO:0006798///polyphosphate catabolic process+++GO:0040009///regulation of growth rate+++GO:0008285///negative regulation of cell proliferation","BCL2 interacting protein like","[BNIPL_HUMAN|Reviewed]RecName: Full=Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein;+++[A2A492_HUMAN|Unreviewed]SubName: Full=Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein {ECO:0000313|Ensembl:ENSP00000355333}; Flags: Fragment;+++[F8W685_HUMAN|Unreviewed]SubName: Full=Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein {ECO:0000313|Ensembl:ENSP00000376550}; Flags: Fragment;"]
[1497,"'CTNS'",728,642,632,667.333333333333,"04142///Lysosome","H00275///Cystinosis",null,null,"GO:0005774///vacuolar membrane+++GO:0045111///intermediate filament cytoskeleton+++GO:0005769///early endosome+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005770///late endosome+++GO:0005764///lysosome+++GO:0070062///extracellular exosome+++GO:0042470///melanosome+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0015184///L-cystine transmembrane transporter activity","GO:0007625///grooming behavior+++GO:0055085///transmembrane transport+++GO:0007616///long-term memory+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0008542///visual learning+++GO:0010730///negative regulation of hydrogen peroxide biosynthetic process+++GO:0006749///glutathione metabolic process+++GO:0006811///ion transport+++GO:0002088///lens development in camera-type eye+++GO:0007420///brain development+++GO:0007628///adult walking behavior+++GO:0046034///ATP metabolic process+++GO:0050890///cognition+++GO:0042438///melanin biosynthetic process+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:0006520///cellular amino acid metabolic process+++GO:0015811///L-cystine transport","cystinosin, lysosomal cystine transporter","[CTNS_HUMAN|Reviewed]RecName: Full=Cystinosin;+++[A0A0S2Z3I9_HUMAN|Unreviewed]SubName: Full=Cystinosis nephropathic isoform 1 {ECO:0000313|EMBL:ALQ33461.1}; Flags: Fragment;+++[A0A0S2Z3K3_HUMAN|Unreviewed]SubName: Full=Cystinosis nephropathic isoform 2 {ECO:0000313|EMBL:ALQ33462.1};+++[A0A0S2Z3L5_HUMAN|Unreviewed]SubName: Full=Cystinosis nephropathic isoform 3 {ECO:0000313|EMBL:ALQ33463.1};+++[A8MXW3_HUMAN|Unreviewed]SubName: Full=Cystinosin {ECO:0000313|Ensembl:ENSP00000382245};+++[C9JMM9_HUMAN|Unreviewed]SubName: Full=Cystinosin {ECO:0000313|Ensembl:ENSP00000408652}; Flags: Fragment;+++[I3L0Z6_HUMAN|Unreviewed]SubName: Full=Cystinosin {ECO:0000313|Ensembl:ENSP00000458457}; Flags: Fragment;+++[I3L1K8_HUMAN|Unreviewed]SubName: Full=Cystinosin {ECO:0000313|Ensembl:ENSP00000458912}; Flags: Fragment;+++[I3L484_HUMAN|Unreviewed]SubName: Full=Cystinosin {ECO:0000313|Ensembl:ENSP00000461056}; SubName: Full=Cystinosis nephropathic isoform 4 {ECO:0000313|EMBL:ALQ33464.1};+++[I3L4A9_HUMAN|Unreviewed]SubName: Full=Cystinosin {ECO:0000313|Ensembl:ENSP00000461118}; Flags: Fragment;+++[Q6FGP9_HUMAN|Unreviewed]SubName: Full=CTNS protein {ECO:0000313|EMBL:CAG46855.1}; Flags: Fragment;"]
[150290,"'DUSP18'",188,126,128,147.333333333333,null,"H01994///Lafora disease+++H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H01892///Peripheral T cell lymphoma (PTCL)+++H01601///Anaplastic large-cell lymphoma",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005743///mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity","GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0000188///inactivation of MAPK activity+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation","dual specificity phosphatase 18","[DUS18_HUMAN|Reviewed]RecName: Full=Dual specificity protein phosphatase 18; EC=3.1.3.16 {ECO:0000269|PubMed:12408986, ECO:0000269|PubMed:12591617}; EC=3.1.3.48 {ECO:0000269|PubMed:12408986, ECO:0000269|PubMed:12591617}; AltName: Full=Low molecular weight dual specificity phosphatase 20 {ECO:0000303|PubMed:12408986}; Short=LMW-DSP20;+++[A0A024R1L2_HUMAN|Unreviewed]SubName: Full=Dual specificity phosphatase 18, isoform CRA_a {ECO:0000313|EMBL:EAW59914.1};+++[C9JEE9_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 18 {ECO:0000313|Ensembl:ENSP00000403378}; Flags: Fragment;+++[F2Z2P2_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 18 {ECO:0000313|Ensembl:ENSP00000384946};+++[F8VX42_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 18 {ECO:0000313|Ensembl:ENSP00000340795}; Flags: Fragment;+++[H7C401_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 18 {ECO:0000313|Ensembl:ENSP00000414825}; Flags: Fragment;"]
[150472,"'CBWD2'",233.85,237.48,215.32,228.883333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","COBW domain containing 2","[CBWD2_HUMAN|Reviewed]RecName: Full=COBW domain-containing protein 2; AltName: Full=Cobalamin synthase W domain-containing protein 2;+++[C9J3G2_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000411906};+++[F8WEG4_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000401945};+++[F8WEU0_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393105};+++[F8WFD0_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000351418};"]
[1509,"'CTSD'",134487,134388,126404,131759.666666667,"04071///Sphingolipid signaling pathway+++04140///Autophagy - animal+++05152///Tuberculosis+++04142///Lysosome+++04210///Apoptosis+++04915///Estrogen signaling pathway","H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H00149///Neuronal ceroid lipofuscinosis (NCL)",null,null,"GO:0070062///extracellular exosome+++GO:0062023///collagen-containing extracellular matrix+++GO:0045121///membrane raft+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005576///extracellular region+++GO:0035580///specific granule lumen+++GO:0042470///melanosome+++GO:0043202///lysosomal lumen+++GO:1904813///ficolin-1-rich granule lumen+++GO:1904724///tertiary granule lumen","GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0004190///aspartic-type endopeptidase activity","GO:0030163///protein catabolic process+++GO:0006508///proteolysis+++GO:0043312///neutrophil degranulation+++GO:0030574///collagen catabolic process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","cathepsin D","[CATD_HUMAN|Reviewed]RecName: Full=Cathepsin D; EC=3.4.23.5; Contains: RecName: Full=Cathepsin D light chain; Contains: RecName: Full=Cathepsin D heavy chain; Flags: Precursor;+++[A0A0S2Z3L4_HUMAN|Unreviewed]SubName: Full=Cathepsin D isoform 2 {ECO:0000313|EMBL:ALQ33466.1}; Flags: Fragment;+++[A0A1B0GV01_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000490316}; Flags: Fragment;+++[A0A1B0GV23_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000490344};+++[A0A1B0GVD5_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000490471};+++[A0A1B0GVP3_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000490598};+++[A0A1B0GW44_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000490770};+++[A0A1B0GWE8_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000490897};+++[C9JH19_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000415036}; Flags: Fragment;+++[F8W787_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000356164}; Flags: Fragment;+++[F8WD96_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000404902};+++[H7C1V0_HUMAN|Unreviewed]SubName: Full=Cathepsin D {ECO:0000313|Ensembl:ENSP00000402586}; Flags: Fragment;+++[V9HWI3_HUMAN|Unreviewed]SubName: Full=Cathepsin D (Lysosomal aspartyl peptidase), isoform CRA_a {ECO:0000313|EMBL:EAX02461.1}; SubName: Full=Cathepsin D isoform 1 {ECO:0000313|EMBL:ALQ33465.1}; SubName: Full=Epididymis secretory sperm binding protein Li 130P {ECO:0000313|EMBL:ACJ13652.1};"]
[151354,"'FAM84A'",724,868,738,776.666666666667,{"$nulls":7},"family with sequence similarity 84 member A","[FA84A_HUMAN|Reviewed]RecName: Full=Protein FAM84A; AltName: Full=Neurologic sensory protein 1; Short=NSE1;"]
[151613,"'TTC14'",261,281,265,269,{"$nulls":5},"GO:0003676///nucleic acid binding",null,"tetratricopeptide repeat domain 14","[TTC14_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 14; Short=TPR repeat protein 14;+++[C9J974_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 14 {ECO:0000313|Ensembl:ENSP00000418126}; Flags: Fragment;+++[C9JBA2_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 14 {ECO:0000313|Ensembl:ENSP00000417415}; Flags: Fragment;+++[C9JCY7_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 14 {ECO:0000313|Ensembl:ENSP00000420652}; Flags: Fragment;+++[F8WDA3_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 14 {ECO:0000313|Ensembl:ENSP00000420732};+++[F8WDH5_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 14 {ECO:0000313|Ensembl:ENSP00000420278};+++[Q69YS0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp313K2110 {ECO:0000313|EMBL:CAH10404.1}; Flags: Fragment;+++[Q86TA5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451L0319 {ECO:0000313|EMBL:CAD89930.1}; Flags: Fragment;+++[Q8TEM7_HUMAN|Unreviewed]SubName: Full=FLJ00166 protein {ECO:0000313|EMBL:BAB84921.1}; Flags: Fragment;"]
[152110,"'NEK10'",43,29,32,34.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:1902911///protein kinase complex","GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0043406///positive regulation of MAP kinase activity+++GO:0031954///positive regulation of protein autophosphorylation+++GO:1902749///regulation of cell cycle G2/M phase transition+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","NIMA related kinase 10","[NEK10_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Nek10; EC=2.7.11.1; AltName: Full=Never in mitosis A-related kinase 10; Short=NimA-related protein kinase 10;+++[A0A0A0MRY8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek10 {ECO:0000313|Ensembl:ENSP00000373280};+++[C9JJN0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek10 {ECO:0000313|Ensembl:ENSP00000395338}; Flags: Fragment;+++[H7C000_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek10 {ECO:0000313|Ensembl:ENSP00000392344}; Flags: Fragment;+++[H7C3L8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek10 {ECO:0000313|Ensembl:ENSP00000412651}; Flags: Fragment;+++[Q8N774_HUMAN|Unreviewed]SubName: Full=cDNA FLJ25966 fis, clone TST05207 {ECO:0000313|EMBL:BAC05427.1};"]
[152330,"'CNTN4'",31,35.73,28,31.5766666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030424///axon+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0005576///extracellular region+++GO:0016020///membrane","GO:0098632///cell-cell adhesion mediator activity","GO:0007411///axon guidance+++GO:0007399///nervous system development+++GO:0007158///neuron cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007409///axonogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0070593///dendrite self-avoidance+++GO:0007420///brain development+++GO:0007413///axonal fasciculation+++GO:0007155///cell adhesion+++GO:0031175///neuron projection development+++GO:0048167///regulation of synaptic plasticity","contactin 4","[CNTN4_HUMAN|Reviewed]RecName: Full=Contactin-4; AltName: Full=Brain-derived immunoglobulin superfamily protein 2; Short=BIG-2; Flags: Precursor;+++[A0A024R2E5_HUMAN|Unreviewed]SubName: Full=Contactin 4, isoform CRA_c {ECO:0000313|EMBL:EAW63878.1};+++[C9JGK9_HUMAN|Unreviewed]SubName: Full=Contactin-4 {ECO:0000313|Ensembl:ENSP00000390560}; Flags: Fragment;+++[C9JIY1_HUMAN|Unreviewed]SubName: Full=Contactin-4 {ECO:0000313|Ensembl:ENSP00000404085}; Flags: Fragment;+++[C9JMQ2_HUMAN|Unreviewed]SubName: Full=Contactin-4 {ECO:0000313|Ensembl:ENSP00000408594}; Flags: Fragment;+++[F8WD58_HUMAN|Unreviewed]SubName: Full=Contactin-4 {ECO:0000313|Ensembl:ENSP00000396719};+++[H0Y8U1_HUMAN|Unreviewed]SubName: Full=Contactin-4 {ECO:0000313|Ensembl:ENSP00000422120}; Flags: Fragment;"]
[152815,"'THAP6'",155,161.01,171,162.336666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015630///microtubule cytoskeleton","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","THAP domain containing 6","[THAP6_HUMAN|Reviewed]RecName: Full=THAP domain-containing protein 6;+++[A0A024RDF9_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_b {ECO:0000313|EMBL:EAX05735.1};+++[D6RBC3_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_e {ECO:0000313|EMBL:EAX05734.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000424255};+++[D6RC19_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000422402}; Flags: Fragment;+++[D6REL7_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426760};+++[D6REQ5_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_d {ECO:0000313|EMBL:EAX05733.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000424949};+++[D6RF27_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426698};+++[D6RFK7_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_a {ECO:0000313|EMBL:EAX05730.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426581};+++[D6RJG2_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000425646}; Flags: Fragment;"]
[153201,"'SLC36A2'",1,1,0,0.666666666666667,"04138///Autophagy - yeast","H01304///Hyperglycinuria+++H00905///Iminoglycinuria",null,null,"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0015187///glycine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0005280///amino acid:proton symporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity","GO:0015816///glycine transport+++GO:0003333///amino acid transmembrane transport+++GO:0015824///proline transport+++GO:0015808///L-alanine transport+++GO:0006811///ion transport+++GO:1902600///proton transmembrane transport+++GO:0006865///amino acid transport+++GO:0035524///proline transmembrane transport","solute carrier family 36 member 2","[S36A2_HUMAN|Reviewed]RecName: Full=Proton-coupled amino acid transporter 2; Short=Proton/amino acid transporter 2; AltName: Full=Solute carrier family 36 member 2; AltName: Full=Tramdorin-1;+++[E5RGH8_HUMAN|Unreviewed]SubName: Full=Proton-coupled amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000430149};+++[E5RJJ5_HUMAN|Unreviewed]SubName: Full=Proton-coupled amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000430535};+++[H0YB43_HUMAN|Unreviewed]SubName: Full=Proton-coupled amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000428634}; Flags: Fragment;"]
[153769,"'SH3RF2'",885,1014,892.95,930.65,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0004864///protein phosphatase inhibitor activity+++GO:0008157///protein phosphatase 1 binding+++GO:0016740///transferase activity+++GO:0019902///phosphatase binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0030335///positive regulation of cell migration+++GO:0051865///protein autoubiquitination+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0043066///negative regulation of apoptotic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0010923///negative regulation of phosphatase activity+++GO:0031397///negative regulation of protein ubiquitination+++GO:0046329///negative regulation of JNK cascade+++GO:0046328///regulation of JNK cascade","SH3 domain containing ring finger 2","[SH3R2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase SH3RF2; EC=2.3.2.27 {ECO:0000269|PubMed:24130170}; AltName: Full=Heart protein phosphatase 1-binding protein; Short=HEPP1; AltName: Full=POSH-eliminating RING protein {ECO:0000303|PubMed:22128169}; AltName: Full=Protein phosphatase 1 regulatory subunit 39; AltName: Full=RING finger protein 158; AltName: Full=RING-type E3 ubiquitin transferase SH3RF2 {ECO:0000305}; AltName: Full=SH3 domain-containing RING finger protein 2;+++[Q08AM8_HUMAN|Unreviewed]SubName: Full=SH3 domain containing ring finger 2 {ECO:0000313|EMBL:AAI25108.1};"]
[154214,"'RNF217'",527,429,425,460.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005829///cytosol","GO:0031624///ubiquitin conjugating enzyme binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0061630///ubiquitin protein ligase activity","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination","ring finger protein 217","[RN217_HUMAN|Reviewed]RecName: Full=Probable E3 ubiquitin-protein ligase RNF217; EC=2.3.2.31 {ECO:0000250|UniProtKB:O60260}; AltName: Full=IBR domain-containing protein 1; AltName: Full=RING finger protein 217;+++[B3KVC8_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};+++[E5RFY6_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase RNF217 {ECO:0000313|Ensembl:ENSP00000357399};+++[H0YB95_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase RNF217 {ECO:0000313|Ensembl:ENSP00000429012}; Flags: Fragment;+++[H0YKH8_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};+++[H3BM17_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase RNF217 {ECO:0000313|Ensembl:ENSP00000404282}; Flags: Fragment;"]
[155061,"'ZNF746'",539,615,512,555.333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0031625///ubiquitin protein ligase binding","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901216///positive regulation of neuron death","zinc finger protein 746","[ZN746_HUMAN|Reviewed]RecName: Full=Zinc finger protein 746; AltName: Full=Parkin-interacting substrate; Short=PARIS;+++[A0A2R8YDQ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 746 {ECO:0000313|Ensembl:ENSP00000493970};+++[C9JNZ9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 746 {ECO:0000313|Ensembl:ENSP00000420329};"]
[1573,"'CYP2J2'",24,32,25,27,"01100///Metabolic pathways+++04726///Serotonergic synapse+++04913///Ovarian steroidogenesis+++00591///Linoleic acid metabolism+++04750///Inflammatory mediator regulation of TRP channels+++00590///Arachidonic acid metabolism+++04212///Longevity regulating pathway - worm",null,null,"R07044///15H-11,12-EETA + H2O <=> 11,12,15-THETA+++R07048///Arachidonate + Oxygen + NADPH + H+ <=> 14,15-EET + NADP+ + H2O+++R07045///11H-14,15-EETA + H2O <=> 11,14,15-THETA+++R07056///Linoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2O+++R07043///15(S)-HPETE <=> 11H-14,15-EETA+++R07042///15(S)-HPETE <=> 15H-11,12-EETA+++R07051///Arachidonate + Oxygen + NADPH + H+ <=> 8,9-EET + NADP+ + H2O+++R07055///Linoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2O+++R07052///Arachidonate + Oxygen + NADPH + H+ <=> 5,6-EET + NADP+ + H2O+++R07046///Arachidonate + Oxygen + NADPH + H+ <=> 19(S)-HETE + NADP+ + H2O+++R07050///Arachidonate + Oxygen + NADPH + H+ <=> 11,12-EET + NADP+ + H2O","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0031090///organelle membrane+++GO:0070062///extracellular exosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0008405///arachidonic acid 11,12-epoxygenase activity+++GO:0004497///monooxygenase activity+++GO:0008404///arachidonic acid 14,15-epoxygenase activity+++GO:0005506///iron ion binding+++GO:0071614///linoleic acid epoxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0070330///aromatase activity+++GO:0008395///steroid hydroxylase activity+++GO:0046872///metal ion binding+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0020037///heme binding+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0008392///arachidonic acid epoxygenase activity","GO:0019373///epoxygenase P450 pathway+++GO:0006805///xenobiotic metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0006082///organic acid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0008016///regulation of heart contraction+++GO:0043651///linoleic acid metabolic process+++GO:0006690///icosanoid metabolic process","cytochrome P450 family 2 subfamily J member 2","[CP2J2_HUMAN|Reviewed]RecName: Full=Cytochrome P450 2J2; EC=1.14.14.1; AltName: Full=Arachidonic acid epoxygenase; AltName: Full=CYPIIJ2;+++[Q96RX4_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:AAK63192.1}; Flags: Fragment;+++[Q9UN91_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 epoxygenase {ECO:0000313|EMBL:AAD30164.1}; Flags: Fragment;"]
[157753,"'TMEM74'",5,5,0,3.33333333333333,{"$nulls":4},"GO:0000421///autophagosome membrane+++GO:0005765///lysosomal membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0006914///autophagy+++GO:0016236///macroautophagy","transmembrane protein 74","[TMM74_HUMAN|Reviewed]RecName: Full=Transmembrane protein 74;+++[A0A024R9D4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 74, isoform CRA_a {ECO:0000313|EMBL:EAW91922.1};"]
[158248,"'TTC16'",4,4,2,3.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","tetratricopeptide repeat domain 16","[TTC16_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 16; Short=TPR repeat protein 16;+++[B4DH05_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60512, highly similar to Tetratricopeptide repeat protein 16 {ECO:0000313|EMBL:BAG57966.1};+++[B4DZ42_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53499, highly similar to Tetratricopeptide repeat protein 16 {ECO:0000313|EMBL:BAG63954.1};"]
[158747,"'MOSPD2'",306,243,255,268,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane",null,"GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0043312///neutrophil degranulation+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0006935///chemotaxis","motile sperm domain containing 2","[MSPD2_HUMAN|Reviewed]RecName: Full=Motile sperm domain-containing protein 2;+++[R4GMN1_HUMAN|Unreviewed]SubName: Full=Motile sperm domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000473271};+++[R4GMW5_HUMAN|Unreviewed]SubName: Full=Motile sperm domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000473379}; Flags: Fragment;+++[R4GNB6_HUMAN|Unreviewed]SubName: Full=Motile sperm domain containing 2, isoform CRA_c {ECO:0000313|EMBL:EAW98866.1}; SubName: Full=Motile sperm domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000473570};"]
[1595,"'CYP51A1'",785,633,650,689.333333333333,"01100///Metabolic pathways+++00100///Steroid biosynthesis+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics",null,"M00101///Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol","R05731///sterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)   Obtusifoliol + 3 Oxygen + 3 NADPH + 3 H+ <=> 4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + Formate + 3 NADP+ + 4 H2O+++R05640///Lanosterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)   Lanosterol + 3 Oxygen + 3 NADPH + 3 H+ <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 3 NADP+ + 4 H2O","GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0031090///organelle membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005783///endoplasmic reticulum","GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0005506///iron ion binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0008398///sterol 14-demethylase activity+++GO:0004497///monooxygenase activity+++GO:0016491///oxidoreductase activity","GO:0006694///steroid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0033488///cholesterol biosynthetic process via 24,25-dihydrolanosterol+++GO:0006695///cholesterol biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0070988///demethylation+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0016125///sterol metabolic process+++GO:0008203///cholesterol metabolic process+++GO:0006629///lipid metabolic process+++GO:0016126///sterol biosynthetic process","cytochrome P450 family 51 subfamily A member 1","[CP51A_HUMAN|Reviewed]RecName: Full=Lanosterol 14-alpha demethylase; Short=LDM; EC=1.14.14.154 {ECO:0000269|PubMed:20149798, ECO:0000269|PubMed:8619637}; AltName: Full=CYPLI; AltName: Full=Cytochrome P450 51A1; AltName: Full=Cytochrome P450-14DM; Short=Cytochrome P45014DM; AltName: Full=Cytochrome P450LI; AltName: Full=Sterol 14-alpha demethylase;+++[A0A0C4DFL7_HUMAN|Unreviewed]SubName: Full=Lanosterol 14-alpha demethylase {ECO:0000313|Ensembl:ENSP00000003100};+++[C9IYR8_HUMAN|Unreviewed]SubName: Full=Lanosterol 14-alpha demethylase {ECO:0000313|Ensembl:ENSP00000412536}; Flags: Fragment;+++[H7C0D0_HUMAN|Unreviewed]SubName: Full=Lanosterol 14-alpha demethylase {ECO:0000313|Ensembl:ENSP00000394268}; Flags: Fragment;+++[Q05D40_HUMAN|Unreviewed]SubName: Full=CYP51A1 protein {ECO:0000313|EMBL:AAH18429.1}; Flags: Fragment;"]
[160419,"'C12orf50'",365.56,489.92,334.16,396.546666666667,{"$nulls":4},"GO:0000346///transcription export complex+++GO:0005623///cell","GO:0003729///mRNA binding+++GO:0005515///protein binding","GO:0016973///poly(A)+ mRNA export from nucleus","chromosome 12 open reading frame 50","[CL050_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C12orf50;+++[F8VSD7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf50 {ECO:0000313|Ensembl:ENSP00000448344};+++[F8VXH4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf50 {ECO:0000313|Ensembl:ENSP00000448855}; Flags: Fragment;"]
[1611,"'DAP'",6609,7325,6701,6878.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0070513///death domain binding","GO:0006915///apoptotic process+++GO:0034198///cellular response to amino acid starvation+++GO:0097190///apoptotic signaling pathway+++GO:0006914///autophagy+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010507///negative regulation of autophagy","death associated protein","[DAP1_HUMAN|Reviewed]RecName: Full=Death-associated protein 1; Short=DAP-1;+++[B4DQ75_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55133, weakly similar to Death-associated protein 1 {ECO:0000313|EMBL:BAG60837.1};"]
[161582,"'DNAAF4'",111,97,87,98.3333333333333,null,"H00564///Primary ciliary dyskinesia+++H01899///Dyslexia",null,null,"GO:0005737///cytoplasm+++GO:0097730///non-motile cilium+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0005886///plasma membrane","GO:0030331///estrogen receptor binding+++GO:0005515///protein binding","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0007507///heart development+++GO:0003351///epithelial cilium movement+++GO:0003341///cilium movement+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007368///determination of left/right symmetry+++GO:0001764///neuron migration+++GO:0036158///outer dynein arm assembly+++GO:0036159///inner dynein arm assembly+++GO:0007399///nervous system development","dynein axonemal assembly factor 4","[DAAF4_HUMAN|Reviewed]RecName: Full=Dynein assembly factor 4, axonemal {ECO:0000312|HGNC:HGNC:21493}; AltName: Full=Dyslexia susceptibility 1 candidate gene 1 protein;+++[A0A0S2Z5X9_HUMAN|Unreviewed]SubName: Full=Dyslexia susceptibility 1 candidate 1 isoform 2 {ECO:0000313|EMBL:ALQ34341.1}; Flags: Fragment;+++[A0A0S2Z5Y0_HUMAN|Unreviewed]SubName: Full=Dyslexia susceptibility 1 candidate 1 isoform 3 {ECO:0000313|EMBL:ALQ34342.1};+++[A0A0S2Z5Z4_HUMAN|Unreviewed]SubName: Full=Dyslexia susceptibility 1 candidate 1 isoform 1 {ECO:0000313|EMBL:ALQ34340.1}; Flags: Fragment;+++[B4DY92_HUMAN|Unreviewed]SubName: Full=Dynein assembly factor 4, axonemal {ECO:0000313|Ensembl:ENSP00000428097}; SubName: Full=cDNA FLJ54204, highly similar to Dyslexia susceptibility 1 candidate gene 1protein {ECO:0000313|EMBL:BAG63654.1};+++[E5RJ13_HUMAN|Unreviewed]SubName: Full=Dynein assembly factor 4, axonemal {ECO:0000313|Ensembl:ENSP00000429219};+++[Q9BQJ6_HUMAN|Unreviewed]SubName: Full=Nuclear protein {ECO:0000313|EMBL:AAK29466.1}; Flags: Fragment;"]
[162333,"'MARCH10'",7,5,7,6.33333333333333,{"$nulls":5},"GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0016567///protein ubiquitination","membrane associated ring-CH-type finger 10","[MARHA_HUMAN|Reviewed]RecName: Full=Probable E3 ubiquitin-protein ligase MARCH10; EC=2.3.2.27; AltName: Full=Membrane-associated RING finger protein 10; AltName: Full=Membrane-associated RING-CH protein X; Short=MARCH-X; AltName: Full=RING finger protein 190; AltName: Full=RING-type E3 ubiquitin transferase MARCH10 {ECO:0000305};+++[A0A140VKA1_HUMAN|Unreviewed]SubName: Full=Testis secretory sperm-binding protein Li 228n {ECO:0000313|EMBL:AEE61238.1};+++[B3KVK0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16660 fis, clone TESTI4042440, moderately similar to Mus musculus axotrophin (Axot) {ECO:0000313|EMBL:BAG53812.1};+++[G3V1Q5_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase MARCH10 {ECO:0000313|Ensembl:ENSP00000443746}; SubName: Full=Ring finger protein 190, isoform CRA_c {ECO:0000313|EMBL:EAW94340.1};+++[J3KTK3_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase MARCH10 {ECO:0000313|Ensembl:ENSP00000463029}; Flags: Fragment;+++[J3KTN9_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase MARCH10 {ECO:0000313|Ensembl:ENSP00000463080}; SubName: Full=Ring finger protein 190, isoform CRA_b {ECO:0000313|EMBL:EAW94339.1};+++[J3QLJ2_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase MARCH10 {ECO:0000313|Ensembl:ENSP00000463572}; Flags: Fragment;+++[J3QRH7_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase MARCH10 {ECO:0000313|Ensembl:ENSP00000464220}; Flags: Fragment;"]
[162963,"'ZNF610'",110,130,130,123.333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 610","[ZN610_HUMAN|Reviewed]RecName: Full=Zinc finger protein 610;+++[M0QYM6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 610 {ECO:0000313|Ensembl:ENSP00000469935}; Flags: Fragment;"]
[163059,"'ZNF433'",40,53,47,46.6666666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 433","[ZN433_HUMAN|Reviewed]RecName: Full=Zinc finger protein 433;+++[A0A024R7H6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433, isoform CRA_b {ECO:0000313|EMBL:EAW84255.1};+++[C9JQA6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000414857}; Flags: Fragment;+++[C9JUV2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000407475}; Flags: Fragment;+++[F8VP42_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000446484};+++[F8VTV7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000448099}; Flags: Fragment;+++[F8VU36_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000447951}; Flags: Fragment;+++[F8VXJ9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000448806}; Flags: Fragment;+++[F8W0C9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000447205}; Flags: Fragment;+++[F8W652_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 433 {ECO:0000313|Ensembl:ENSP00000448233}; Flags: Fragment;"]
[163087,"'ZNF383'",74,70,60,68,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 383","[ZN383_HUMAN|Reviewed]RecName: Full=Zinc finger protein 383;+++[K7EJN0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 383 {ECO:0000313|Ensembl:ENSP00000465246}; Flags: Fragment;+++[K7ELW4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 383 {ECO:0000313|Ensembl:ENSP00000466246};"]
[1639,"'DCTN1'",6826,6930,6313,6689.66666666667,"05016///Huntington's disease+++04962///Vasopressin-regulated water reabsorption","H00879///Perry syndrome+++H00058///Amyotrophic lateral sclerosis (ALS)+++H00856///Distal hereditary motor neuropathies (dHMN)",null,null,"GO:0030286///dynein complex+++GO:0045111///intermediate filament cytoskeleton+++GO:0035371///microtubule plus-end+++GO:0030904///retromer complex+++GO:0005815///microtubule organizing center+++GO:0000922///spindle pole+++GO:0099738///cell cortex region+++GO:0005874///microtubule+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030424///axon+++GO:0005819///spindle+++GO:0005938///cell cortex+++GO:0000776///kinetochore+++GO:0005635///nuclear envelope+++GO:0005875///microtubule associated complex+++GO:0005814///centriole+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0005829///cytosol+++GO:0005869///dynactin complex+++GO:0005813///centrosome+++GO:0120103///centriolar subdistal appendage","GO:0019901///protein kinase binding+++GO:0048156///tau protein binding+++GO:0003774///motor activity+++GO:0015631///tubulin binding+++GO:0008017///microtubule binding+++GO:0070840///dynein complex binding+++GO:0005515///protein binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0098930///axonal transport+++GO:0021517///ventral spinal cord development+++GO:0007049///cell cycle+++GO:0070050///neuron cellular homeostasis+++GO:0051301///cell division+++GO:0007528///neuromuscular junction development+++GO:0099558///maintenance of synapse structure+++GO:0034454///microtubule anchoring at centrosome+++GO:0010970///transport along microtubule+++GO:0050905///neuromuscular process+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0090063///positive regulation of microtubule nucleation+++GO:1990535///neuron projection maintenance+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0000278///mitotic cell cycle+++GO:0061744///motor behavior+++GO:0010457///centriole-centriole cohesion+++GO:0000132///establishment of mitotic spindle orientation+++GO:1905515///non-motile cilium assembly+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0031116///positive regulation of microtubule polymerization+++GO:0007399///nervous system development+++GO:0060236///regulation of mitotic spindle organization+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0051081///nuclear envelope disassembly+++GO:1904398///positive regulation of neuromuscular junction development","dynactin subunit 1","[DCTN1_HUMAN|Reviewed]RecName: Full=Dynactin subunit 1; AltName: Full=150 kDa dynein-associated polypeptide; AltName: Full=DAP-150; Short=DP-150; AltName: Full=p135; AltName: Full=p150-glued;+++[C9J1B7_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000400059}; Flags: Fragment;+++[C9JJD0_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000404038}; Flags: Fragment;+++[C9JJN7_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000395312}; Flags: Fragment;+++[C9JKG6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000402509}; Flags: Fragment;+++[C9JTE5_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000409363}; Flags: Fragment;+++[C9JUI8_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000407484}; Flags: Fragment;+++[C9JZA4_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000413268}; Flags: Fragment;+++[E7EX90_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000387327};+++[E9PCY0_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000414315}; Flags: Fragment;+++[L8EA71_HUMAN|Unreviewed]SubName: Full=Alternative protein DCTN1 {ECO:0000313|EMBL:CCQ43248.1};+++[Q6AWB1_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 1 {ECO:0000313|Ensembl:ENSP00000416711};+++[Q6MZZ3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686I0746 {ECO:0000313|EMBL:CAE45882.1};"]
[164091,"'PAQR7'",294.93,266,254,271.643333333333,null,"H01310///Multi-minicore disease (MmD)+++H00590///Congenital muscular dystrophies (CMD/MDC)+++H00701///Congenital fiber type disproportion (CFTD)",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0038023///signaling receptor activity","GO:0030154///cell differentiation+++GO:0048477///oogenesis+++GO:0007275///multicellular organism development","progestin and adipoQ receptor family member 7","[PAQR7_HUMAN|Reviewed]RecName: Full=Membrane progestin receptor alpha {ECO:0000303|PubMed:23763432}; Short=mPR alpha {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone P4 receptor alpha {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone receptor alpha {ECO:0000303|PubMed:23763432}; AltName: Full=Progesterone and adipoQ receptor family member 7; AltName: Full=Progestin and adipoQ receptor family member 7 {ECO:0000303|PubMed:16044242}; AltName: Full=Progestin and adipoQ receptor family member VII;+++[A1L182_HUMAN|Unreviewed]SubName: Full=PAQR7 protein {ECO:0000313|EMBL:AAI27801.1}; Flags: Fragment;"]
[164684,"'WBP2NL'",4,2,4,3.33333333333333,"01100///Metabolic pathways+++04142///Lysosome+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series","H00422///Glycoproteinoses+++H00146///Alpha-N-acetylgalactosaminidase deficiency",null,"R05966///H2O + Forssman antigen, IV3GalNAca-Gb4Cer <=> N-Acetyl-D-galactosamine + Globoside","GO:0005634///nucleus+++GO:0036126///sperm flagellum+++GO:0061827///sperm head+++GO:0033011///perinuclear theca","GO:0050699///WW domain binding+++GO:0031490///chromatin DNA binding+++GO:0003713///transcription coactivator activity","GO:0035039///male pronucleus assembly+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0007343///egg activation+++GO:0051321///meiotic cell cycle+++GO:0035038///female pronucleus assembly+++GO:1903508///positive regulation of nucleic acid-templated transcription","WBP2 N-terminal like","[WBP2L_HUMAN|Reviewed]RecName: Full=Postacrosomal sheath WW domain-binding protein; AltName: Full=WW domain-binding protein 2-like;+++[F5H7L2_HUMAN|Unreviewed]SubName: Full=Postacrosomal sheath WW domain-binding protein {ECO:0000313|Ensembl:ENSP00000442447};+++[F8WCF8_HUMAN|Unreviewed]SubName: Full=Postacrosomal sheath WW domain-binding protein {ECO:0000313|Ensembl:ENSP00000400236};+++[F8WDR4_HUMAN|Unreviewed]SubName: Full=Postacrosomal sheath WW domain-binding protein {ECO:0000313|Ensembl:ENSP00000389598};+++[L8E9M8_HUMAN|Unreviewed]SubName: Full=Alternative protein WBP2NL {ECO:0000313|EMBL:CCQ43859.1};"]
[165324,"'UBXN2A'",191,230,182,201,{"$nulls":4},"GO:0005801///cis-Golgi network+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0043130///ubiquitin binding+++GO:0033130///acetylcholine receptor binding","GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0010468///regulation of gene expression+++GO:0031468///nuclear envelope reassembly+++GO:0007030///Golgi organization+++GO:0042176///regulation of protein catabolic process+++GO:0031396///regulation of protein ubiquitination+++GO:0000045///autophagosome assembly+++GO:0061025///membrane fusion+++GO:1990830///cellular response to leukemia inhibitory factor","UBX domain protein 2A","[UBX2A_HUMAN|Reviewed]RecName: Full=UBX domain-containing protein 2A; AltName: Full=UBX domain-containing protein 4;"]
[166379,"'BBS12'",93,84,69,82,null,"H00418///Bardet-Biedl syndrome (BBS)",null,null,"GO:0042995///cell projection+++GO:0005929///cilium","GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0045494///photoreceptor cell maintenance+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0045599///negative regulation of fat cell differentiation+++GO:0042073///intraciliary transport+++GO:0042755///eating behavior","Bardet-Biedl syndrome 12","[BBS12_HUMAN|Reviewed]RecName: Full=Bardet-Biedl syndrome 12 protein;+++[A0A1B1SMW0_HUMAN|Unreviewed]SubName: Full=Truncated Bardet-Biedl syndrome 12 protein {ECO:0000313|EMBL:ANV22097.1};+++[C9J8H7_HUMAN|Unreviewed]SubName: Full=Bardet-Biedl syndrome 12 protein {ECO:0000313|Ensembl:ENSP00000398912}; Flags: Fragment;"]
[166968,"'MIER3'",162,144,152,152.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm","GO:0003714///transcription corepressor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0042826///histone deacetylase binding+++GO:0004407///histone deacetylase activity","GO:0016575///histone deacetylation+++GO:0000122///negative regulation of transcription by RNA polymerase II","MIER family member 3","[MIER3_HUMAN|Reviewed]RecName: Full=Mesoderm induction early response protein 3; Short=Mi-er3;+++[A8MQD4_HUMAN|Unreviewed]SubName: Full=Mesoderm induction early response protein 3 {ECO:0000313|Ensembl:ENSP00000337027}; Flags: Fragment;+++[C9JXP7_HUMAN|Unreviewed]SubName: Full=Mesoderm induction early response protein 3 {ECO:0000313|Ensembl:ENSP00000407169}; Flags: Fragment;+++[H7C1J9_HUMAN|Unreviewed]SubName: Full=Mesoderm induction early response protein 3 {ECO:0000313|Ensembl:ENSP00000400693}; Flags: Fragment;"]
[168507,"'PKD1L1'",37,24,20,27,null,"H00632///Heterotaxy",null,null,"GO:0042995///cell projection+++GO:0005929///cilium+++GO:0034704///calcium channel complex+++GO:0060170///ciliary membrane+++GO:0016021///integral component of membrane+++GO:0097730///non-motile cilium+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0005262///calcium channel activity","GO:0006811///ion transport+++GO:0050982///detection of mechanical stimulus+++GO:0070588///calcium ion transmembrane transport+++GO:0003127///detection of nodal flow+++GO:0070986///left/right axis specification+++GO:0098609///cell-cell adhesion+++GO:0006816///calcium ion transport","polycystin 1 like 1, transient receptor potential channel interacting","[PK1L1_HUMAN|Reviewed]RecName: Full=Polycystic kidney disease protein 1-like 1; AltName: Full=PC1-like 1 protein; AltName: Full=Polycystin-1L1;+++[H7C083_HUMAN|Unreviewed]SubName: Full=Polycystic kidney disease protein 1-like 1 {ECO:0000313|Ensembl:ENSP00000393466}; Flags: Fragment;"]
[169200,"'TMEM64'",221,186,221,209.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum",null,"GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045600///positive regulation of fat cell differentiation+++GO:0045780///positive regulation of bone resorption+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0043462///regulation of ATPase activity","transmembrane protein 64","[TMM64_HUMAN|Reviewed]RecName: Full=Transmembrane protein 64;+++[B3KW24_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 64 {ECO:0000313|EMBL:EAW91668.1}; SubName: Full=cDNA FLJ41964 fis, clone PUAEN2006701, highly similar to Homo sapiens transmembrane protein 64 (TMEM64), mRNA {ECO:0000313|EMBL:BAG53986.1};+++[E5RIS8_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 64 {ECO:0000313|Ensembl:ENSP00000430689}; Flags: Fragment;+++[H0Y6S7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 64 {ECO:0000313|Ensembl:ENSP00000407617}; Flags: Fragment;"]
[170371,"'TMEM273'",2,2,0,1.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 273","[TM273_HUMAN|Reviewed]RecName: Full=Transmembrane protein 273 {ECO:0000305}; Flags: Precursor;+++[A0A0A0MRR9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 273 {ECO:0000313|Ensembl:ENSP00000363266};+++[G3V182_HUMAN|Unreviewed]SubName: Full=HCG1653562, isoform CRA_g {ECO:0000313|EMBL:EAW93111.1}; SubName: Full=Transmembrane protein 273 {ECO:0000313|Ensembl:ENSP00000432859};+++[Q5T290_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 273 {ECO:0000313|Ensembl:ENSP00000395067}; Flags: Fragment;"]
[170961,"'ANKRD24'",39,86,53,59.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity","GO:0010468///regulation of gene expression","ankyrin repeat domain 24","[ANR24_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 24;+++[M0QZ18_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 24 {ECO:0000313|Ensembl:ENSP00000470227}; Flags: Fragment;+++[M0R0N9_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 24 {ECO:0000313|Ensembl:ENSP00000471346}; Flags: Fragment;"]
[171425,"'CLYBL'",88,167.94,146,133.98,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0004474///malate synthase activity+++GO:0016829///lyase activity+++GO:0003824///catalytic activity+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0047777///(3S)-citramalyl-CoA lyase activity","GO:0070207///protein homotrimerization+++GO:0106064///regulation of cobalamin metabolic process","citrate lyase beta like","[CLYBL_HUMAN|Reviewed]RecName: Full=Citramalyl-CoA lyase, mitochondrial {ECO:0000303|PubMed:29056341}; EC=4.1.3.25 {ECO:0000269|PubMed:29056341}; AltName: Full=Beta-methylmalate synthase; EC=2.3.3.- {ECO:0000269|PubMed:24334609, ECO:0000269|PubMed:29056341}; AltName: Full=Citrate lyase subunit beta-like protein {ECO:0000305}; Short=Citrate lyase beta-like {ECO:0000305}; AltName: Full=Malate synthase; EC=2.3.3.9 {ECO:0000269|PubMed:24334609, ECO:0000269|PubMed:29056341}; Flags: Precursor;+++[A0A024RE03_HUMAN|Unreviewed]SubName: Full=Citrate lyase beta like, isoform CRA_a {ECO:0000313|EMBL:EAX09025.1};+++[Q5JVB9_HUMAN|Unreviewed]SubName: Full=Citramalyl-CoA lyase, mitochondrial {ECO:0000313|Ensembl:ENSP00000389062}; Flags: Fragment;+++[Q5JVC0_HUMAN|Unreviewed]SubName: Full=Citramalyl-CoA lyase, mitochondrial {ECO:0000313|Ensembl:ENSP00000396574}; Flags: Fragment;+++[Q5JVC1_HUMAN|Unreviewed]SubName: Full=Citramalyl-CoA lyase, mitochondrial {ECO:0000313|Ensembl:ENSP00000401586}; Flags: Fragment;+++[Q5JVC2_HUMAN|Unreviewed]SubName: Full=Citramalyl-CoA lyase, mitochondrial {ECO:0000313|Ensembl:ENSP00000403408}; Flags: Fragment;"]
[1742,"'DLG4'",333,490,417,413.333333333333,"05016///Huntington's disease+++04390///Hippo signaling pathway+++04724///Glutamatergic synapse+++05030///Cocaine addiction",{"$nulls":3},"GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005829///cytosol+++GO:0044300///cerebellar mossy fiber+++GO:0032281///AMPA glutamate receptor complex+++GO:0044224///juxtaparanode region of axon+++GO:0060076///excitatory synapse+++GO:0008021///synaptic vesicle+++GO:0045177///apical part of cell+++GO:0031410///cytoplasmic vesicle+++GO:0016235///aggresome+++GO:0098978///glutamatergic synapse+++GO:0005634///nucleus+++GO:0032839///dendrite cytoplasm+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0098839///postsynaptic density membrane+++GO:0044309///neuron spine+++GO:0016328///lateral plasma membrane+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0030863///cortical cytoskeleton+++GO:0016323///basolateral plasma membrane+++GO:0043197///dendritic spine+++GO:0030054///cell junction+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0044306///neuron projection terminus+++GO:0030666///endocytic vesicle membrane","GO:0097109///neuroligin family protein binding+++GO:0019904///protein domain specific binding+++GO:0048365///Rac GTPase binding+++GO:0031812///P2Y1 nucleotide receptor binding+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0019900///kinase binding+++GO:0005109///frizzled binding+++GO:0031748///D1 dopamine receptor binding+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0042802///identical protein binding+++GO:0004385///guanylate kinase activity+++GO:0008022///protein C-terminus binding+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0043621///protein self-association+++GO:0030165///PDZ domain binding+++GO:0033130///acetylcholine receptor binding+++GO:0019903///protein phosphatase binding+++GO:0015276///ligand-gated ion channel activity","GO:0035329///hippo signaling+++GO:0061024///membrane organization+++GO:0045184///establishment of protein localization+++GO:0071625///vocalization behavior+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0097113///AMPA glutamate receptor clustering+++GO:1904886///beta-catenin destruction complex disassembly+++GO:0090103///cochlea morphogenesis+++GO:0097120///receptor localization to synapse+++GO:0035865///cellular response to potassium ion+++GO:0001934///positive regulation of protein phosphorylation+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0002091///negative regulation of receptor internalization+++GO:0051259///protein complex oligomerization+++GO:0003151///outflow tract morphogenesis+++GO:0001843///neural tube closure+++GO:0007507///heart development+++GO:0007399///nervous system development+++GO:0050806///positive regulation of synaptic transmission+++GO:0060070///canonical Wnt signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0035418///protein localization to synapse+++GO:0043547///positive regulation of GTPase activity+++GO:0035641///locomotory exploration behavior+++GO:0050885///neuromuscular process controlling balance+++GO:0034613///cellular protein localization+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:2000821///regulation of grooming behavior+++GO:2000310///regulation of NMDA receptor activity+++GO:0060997///dendritic spine morphogenesis+++GO:0035176///social behavior+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0007165///signal transduction+++GO:0016188///synaptic vesicle maturation+++GO:0150012///positive regulation of neuron projection arborization+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0007612///learning+++GO:0000165///MAPK cascade+++GO:0044340///canonical Wnt signaling pathway involved in regulation of cell proliferation+++GO:0007379///segment specification+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0043507///positive regulation of JUN kinase activity+++GO:0065003///protein-containing complex assembly+++GO:0022007///convergent extension involved in neural plate elongation","discs large MAGUK scaffold protein 4","[DLG4_HUMAN|Reviewed]RecName: Full=Disks large homolog 4; AltName: Full=Postsynaptic density protein 95; Short=PSD-95; AltName: Full=Synapse-associated protein 90; Short=SAP-90; Short=SAP90;+++[B7Z4H2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50577, highly similar to Discs large homolog 4 {ECO:0000313|EMBL:BAH12558.1};+++[B7Z647_HUMAN|Unreviewed]SubName: Full=Discs, large homolog 4 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW90252.1}; SubName: Full=cDNA FLJ50646, highly similar to Discs large homolog 4 {ECO:0000313|EMBL:BAH13133.1}; SubName: Full=cDNA, FLJ78995, highly similar to Discs large homolog 4 {ECO:0000313|EMBL:BAH14467.1};+++[B9EGL1_HUMAN|Unreviewed]SubName: Full=DLG4 protein {ECO:0000313|EMBL:AAI36554.1}; SubName: Full=Discs, large homolog 4 (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAW90253.1};"]
[1755,"'DMBT1'",3,0,0,1,"04970///Salivary secretion",{"$nulls":3},"GO:0005576///extracellular region+++GO:0042589///zymogen granule membrane+++GO:0009897///external side of plasma membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0070062///extracellular exosome+++GO:0019898///extrinsic component of membrane","GO:0048306///calcium-dependent protein binding+++GO:0008329///signaling pattern recognition receptor activity+++GO:0070891///lipoteichoic acid binding+++GO:0035375///zymogen binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0005044///scavenger receptor activity+++GO:1904399///heparan sulfate binding+++GO:0001530///lipopolysaccharide binding+++GO:0038187///pattern recognition receptor activity","GO:0015031///protein transport+++GO:0050829///defense response to Gram-negative bacterium+++GO:0050830///defense response to Gram-positive bacterium+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0002221///pattern recognition receptor signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0007275///multicellular organism development+++GO:0030855///epithelial cell differentiation+++GO:0030154///cell differentiation+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0043152///induction of bacterial agglutination+++GO:0016032///viral process+++GO:0006898///receptor-mediated endocytosis","deleted in malignant brain tumors 1","[DMBT1_HUMAN|Reviewed]RecName: Full=Deleted in malignant brain tumors 1 protein; AltName: Full=Glycoprotein 340; Short=Gp-340; AltName: Full=Hensin; AltName: Full=Salivary agglutinin; Short=SAG; AltName: Full=Surfactant pulmonary-associated D-binding protein; Flags: Precursor;+++[B6V682_HUMAN|Unreviewed]SubName: Full=Deleted in malignant brain tumors 1 {ECO:0000313|EMBL:ACI95281.1}; Flags: Fragment;+++[L8E969_HUMAN|Unreviewed]SubName: Full=Alternative protein DMBT1 {ECO:0000313|EMBL:CCQ43261.1};"]
[1777,"'DNASE2'",1863,1804,1530,1732.33333333333,"04142///Lysosome",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005764///lysosome","GO:0003677///DNA binding+++GO:0016787///hydrolase activity+++GO:0004531///deoxyribonuclease II activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0004518///nuclease activity","GO:0006259///DNA metabolic process+++GO:0050776///regulation of immune response+++GO:0006308///DNA catabolic process+++GO:0030218///erythrocyte differentiation+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0006309///apoptotic DNA fragmentation+++GO:0000737///DNA catabolic process, endonucleolytic","deoxyribonuclease 2, lysosomal","[DNS2A_HUMAN|Reviewed]RecName: Full=Deoxyribonuclease-2-alpha; EC=3.1.22.1; AltName: Full=Acid DNase; AltName: Full=Deoxyribonuclease II alpha; Short=DNase II alpha; AltName: Full=Lysosomal DNase II; AltName: Full=R31240_2; Flags: Precursor;+++[A0A024R7F4_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease II, lysosomal, isoform CRA_a {ECO:0000313|EMBL:EAW84322.1};+++[K7ENE5_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-2-alpha {ECO:0000313|Ensembl:ENSP00000466912}; Flags: Fragment;+++[Q96TC5_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease II {ECO:0000313|EMBL:BAB55597.1}; Flags: Fragment;+++[Q9H3R9_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease II {ECO:0000313|EMBL:BAB20386.1}; Flags: Fragment;"]
[1793,"'DOCK1'",1369,1459,1361,1396.33333333333,"05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++04510///Focal adhesion+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0017124///SH3 domain binding","GO:0007229///integrin-mediated signaling pathway+++GO:0006915///apoptotic process+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0006911///phagocytosis, engulfment+++GO:0006909///phagocytosis+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016477///cell migration+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007010///cytoskeleton organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0007596///blood coagulation+++GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0002244///hematopoietic progenitor cell differentiation","dedicator of cytokinesis 1","[DOCK1_HUMAN|Reviewed]RecName: Full=Dedicator of cytokinesis protein 1; AltName: Full=180 kDa protein downstream of CRK; Short=DOCK180;+++[A0A096LNH6_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 1 {ECO:0000313|Ensembl:ENSP00000485033};+++[A0A2X0U2H5_HUMAN|Unreviewed]SubName: Full=DOCK1 {ECO:0000313|EMBL:SPT35741.1}; Flags: Fragment;+++[B2RUU3_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 1 {ECO:0000313|EMBL:AAI46858.1};"]
[182,"'JAG1'",183,141,181,168.333333333333,"01522///Endocrine resistance+++05165///Human papillomavirus infection+++04371///Apelin signaling pathway+++04668///TNF signaling pathway+++04658///Th1 and Th2 cell differentiation+++04330///Notch signaling pathway+++05200///Pathways in cancer+++05224///Breast cancer","H00551///Alagille syndrome+++H00549///Tetralogy of Fallot",null,null,"GO:0005912///adherens junction+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0045177///apical part of cell+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016324///apical plasma membrane","GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0005112///Notch binding+++GO:0008083///growth factor activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding","GO:0061314///Notch signaling involved in heart development+++GO:0001709///cell fate determination+++GO:0030097///hemopoiesis+++GO:0010469///regulation of signaling receptor activity+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0001525///angiogenesis+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0002011///morphogenesis of an epithelial sheet+++GO:0061073///ciliary body morphogenesis+++GO:0003184///pulmonary valve morphogenesis+++GO:0060411///cardiac septum morphogenesis+++GO:0097150///neuronal stem cell population maintenance+++GO:0030216///keratinocyte differentiation+++GO:0072070///loop of Henle development+++GO:0007399///nervous system development+++GO:0002456///T cell mediated immunity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:2000737///negative regulation of stem cell differentiation+++GO:0007275///multicellular organism development+++GO:0061156///pulmonary artery morphogenesis+++GO:0045445///myoblast differentiation+++GO:0048839///inner ear development+++GO:0001974///blood vessel remodeling+++GO:0072017///distal tubule development+++GO:0045599///negative regulation of fat cell differentiation+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0009887///animal organ morphogenesis+++GO:0030336///negative regulation of cell migration+++GO:0007154///cell communication+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0035909///aorta morphogenesis+++GO:0061444///endocardial cushion cell development+++GO:0007219///Notch signaling pathway+++GO:0072006///nephron development+++GO:0032495///response to muramyl dipeptide+++GO:0072015///glomerular visceral epithelial cell development+++GO:0003180///aortic valve morphogenesis+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0042127///regulation of cell proliferation+++GO:0045596///negative regulation of cell differentiation+++GO:0062043///positive regulation of cardiac epithelial to mesenchymal transition+++GO:0061309///cardiac neural crest cell development involved in outflow tract morphogenesis+++GO:0045639///positive regulation of myeloid cell differentiation+++GO:0045446///endothelial cell differentiation+++GO:0043010///camera-type eye development+++GO:0045665///negative regulation of neuron differentiation","jagged 1","[JAG1_HUMAN|Reviewed]RecName: Full=Protein jagged-1; Short=Jagged1; Short=hJ1; AltName: CD_antigen=CD339; Flags: Precursor;+++[A0A087WXH5_HUMAN|Unreviewed]SubName: Full=Protein jagged-1 {ECO:0000313|Ensembl:ENSP00000481034}; Flags: Fragment;+++[A0A087X1E8_HUMAN|Unreviewed]SubName: Full=Protein jagged-1 {ECO:0000313|Ensembl:ENSP00000484139}; Flags: Fragment;+++[B5M914_HUMAN|Unreviewed]SubName: Full=Jagged 1 {ECO:0000313|EMBL:ACH41921.1}; Flags: Fragment;+++[B7U6M8_HUMAN|Unreviewed]SubName: Full=Jagged 1 {ECO:0000313|EMBL:ACJ68516.1}; Flags: Fragment;+++[B7U6M9_HUMAN|Unreviewed]SubName: Full=Jagged 1 {ECO:0000313|EMBL:ACJ68517.1}; Flags: Fragment;+++[Q4KMR2_HUMAN|Unreviewed]RecName: Full=Delta-like protein {ECO:0000256|RuleBase:RU280815};+++[Q99740_HUMAN|Unreviewed]SubName: Full=Soluble protein Jagged {ECO:0000313|EMBL:AAC50909.1}; Flags: Fragment;"]
[1831,"'TSC22D3'",764,719,712,731.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding","GO:0034220///ion transmembrane transport+++GO:0070236///negative regulation of activation-induced cell death of T cells+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006970///response to osmotic stress","TSC22 domain family member 3","[T22D3_HUMAN|Reviewed]RecName: Full=TSC22 domain family protein 3; AltName: Full=DSIP-immunoreactive peptide; Short=Protein DIP; Short=hDIP; AltName: Full=Delta sleep-inducing peptide immunoreactor; AltName: Full=Glucocorticoid-induced leucine zipper protein; Short=GILZ; AltName: Full=TSC-22-like protein; AltName: Full=TSC-22-related protein; Short=TSC-22R;+++[D6R8Z7_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000422228}; Flags: Fragment;+++[D6R9J1_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000422060}; Flags: Fragment;+++[D6RAX8_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000424653}; Flags: Fragment;+++[D6RBL1_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000422636}; Flags: Fragment;+++[D6RCK9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000427199}; Flags: Fragment;+++[D6RD37_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000427075}; Flags: Fragment;+++[D6RD92_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000425414}; Flags: Fragment;+++[D6RDZ7_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000425158}; Flags: Fragment;+++[D6RDZ9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000425155}; Flags: Fragment;+++[E7EWD5_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000421016};+++[Q5JRJ0_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000361457};+++[Q5JRJ2_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000361466};"]
[1852,"'DUSP9'",2,2,4,2.66666666666667,"04550///Signaling pathways regulating pluripotency of stem cells+++04010///MAPK signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004725///protein tyrosine phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0000187///activation of MAPK activity+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0000188///inactivation of MAPK activity+++GO:0016311///dephosphorylation+++GO:0006470///protein dephosphorylation+++GO:0000165///MAPK cascade+++GO:0007254///JNK cascade","dual specificity phosphatase 9","[DUS9_HUMAN|Reviewed]RecName: Full=Dual specificity protein phosphatase 9; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=Mitogen-activated protein kinase phosphatase 4; Short=MAP kinase phosphatase 4; Short=MKP-4;+++[B2RAL9_HUMAN|Unreviewed]RecName: Full=Dual specificity protein phosphatase {ECO:0000256|PIRNR:PIRNR000939}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR000939}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR000939};+++[Q6P9C2_HUMAN|Unreviewed]RecName: Full=Dual specificity protein phosphatase {ECO:0000256|PIRNR:PIRNR000939}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR000939}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR000939};"]
[1889,"'ECE1'",1382,1225,1253,1286.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0033093///Weibel-Palade body+++GO:0016021///integral component of membrane+++GO:0009897///external side of plasma membrane+++GO:0005765///lysosomal membrane+++GO:0031982///vesicle+++GO:0031302///intrinsic component of endosome membrane+++GO:0070062///extracellular exosome","GO:0046872///metal ion binding+++GO:0004175///endopeptidase activity+++GO:0008270///zinc ion binding+++GO:0004222///metalloendopeptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0008237///metallopeptidase activity+++GO:0042803///protein homodimerization activity+++GO:0017046///peptide hormone binding","GO:0016485///protein processing+++GO:0001921///positive regulation of receptor recycling+++GO:0016486///peptide hormone processing+++GO:0003100///regulation of systemic arterial blood pressure by endothelin+++GO:0007507///heart development+++GO:0010815///bradykinin catabolic process+++GO:0010814///substance P catabolic process+++GO:0034959///endothelin maturation+++GO:0060037///pharyngeal system development+++GO:0019229///regulation of vasoconstriction+++GO:0042447///hormone catabolic process+++GO:0006508///proteolysis+++GO:0042733///embryonic digit morphogenesis+++GO:0043583///ear development+++GO:0010816///calcitonin catabolic process","endothelin converting enzyme 1","[ECE1_HUMAN|Reviewed]RecName: Full=Endothelin-converting enzyme 1; Short=ECE-1; EC=3.4.24.71;+++[A0A024RAB0_HUMAN|Unreviewed]SubName: Full=Endothelin converting enzyme 1, isoform CRA_a {ECO:0000313|EMBL:EAW94961.1};+++[A0A024RAB2_HUMAN|Unreviewed]SubName: Full=Endothelin converting enzyme 1, isoform CRA_c {ECO:0000313|EMBL:EAW94966.1};+++[A0A024RAF7_HUMAN|Unreviewed]SubName: Full=Endothelin converting enzyme 1, isoform CRA_b {ECO:0000313|EMBL:EAW94965.1};+++[B4DKB2_HUMAN|Unreviewed]SubName: Full=Endothelin-converting enzyme 1 {ECO:0000313|Ensembl:ENSP00000388439}; SubName: Full=cDNA FLJ59212, highly similar to Endothelin-converting enzyme 1 {ECO:0000313|EMBL:BAG59124.1};+++[E9PHZ1_HUMAN|Unreviewed]SubName: Full=Endothelin-converting enzyme 1 {ECO:0000313|Ensembl:ENSP00000436633}; Flags: Fragment;+++[E9PJG1_HUMAN|Unreviewed]SubName: Full=Endothelin-converting enzyme 1 {ECO:0000313|Ensembl:ENSP00000431856}; Flags: Fragment;+++[E9PN99_HUMAN|Unreviewed]SubName: Full=Endothelin-converting enzyme 1 {ECO:0000313|Ensembl:ENSP00000432860}; Flags: Fragment;"]
[1909,"'EDNRA'",94,86,62,80.6666666666667,"04024///cAMP signaling pathway+++04270///Vascular smooth muscle contraction+++04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++05200///Pathways in cancer+++04924///Renin secretion+++04022///cGMP-PKG signaling pathway",null,null,"R11218///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming) S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11220///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming) 2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0005515///protein binding+++GO:0004962///endothelin receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004435///phosphatidylinositol phospholipase C activity","GO:0014032///neural crest cell development+++GO:0007165///signal transduction+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0014824///artery smooth muscle contraction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0001666///response to hypoxia+++GO:0048484///enteric nervous system development+++GO:0086100///endothelin receptor signaling pathway+++GO:0007190///activation of adenylate cyclase activity+++GO:0042310///vasoconstriction+++GO:0001701///in utero embryonic development+++GO:0008217///regulation of blood pressure+++GO:0008283///cell proliferation+++GO:0060322///head development+++GO:0007507///heart development+++GO:0006939///smooth muscle contraction+++GO:0010827///regulation of glucose transmembrane transport+++GO:0007585///respiratory gaseous exchange+++GO:0007202///activation of phospholipase C activity","endothelin receptor type A","[EDNRA_HUMAN|Reviewed]RecName: Full=Endothelin-1 receptor {ECO:0000305}; AltName: Full=Endothelin receptor type A {ECO:0000312|HGNC:HGNC:3179}; Short=ET-A; Short=ETA-R; Short=hET-AR; Flags: Precursor;"]
[1939,"'EIF2D'",861,974,929,921.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0022627///cytosolic small ribosomal subunit","GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0038023///signaling receptor activity","GO:0006886///intracellular protein transport+++GO:0075522///IRES-dependent viral translational initiation+++GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0032790///ribosome disassembly","eukaryotic translation initiation factor 2D","[EIF2D_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 2D; Short=eIF2d; AltName: Full=Hepatocellular carcinoma-associated antigen 56; AltName: Full=Ligatin;+++[A0A087WVB6_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000479327}; Flags: Fragment;+++[A0A087X1L6_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000484299}; Flags: Fragment;+++[A0A087X202_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000484590}; Flags: Fragment;+++[Q5SY38_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000394685}; Flags: Fragment;"]
[1956,"'EGFR'",4222,5200,4159,4527,"05225///Hepatocellular carcinoma+++05231///Choline metabolism in cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05223///Non-small cell lung cancer+++04630///Jak-STAT signaling pathway+++04012///ErbB signaling pathway+++04540///Gap junction+++04144///Endocytosis+++04014///Ras signaling pathway+++05226///Gastric cancer+++05206///MicroRNAs in cancer+++04926///Relaxin signaling pathway+++04810///Regulation of actin cytoskeleton+++04010///MAPK signaling pathway+++05212///Pancreatic cancer+++04013///MAPK signaling pathway - fly+++05224///Breast cancer+++04912///GnRH signaling pathway+++05214///Glioma+++05218///Melanoma+++04320///Dorso-ventral axis formation+++04214///Apoptosis - fly+++05160///Hepatitis C+++05165///Human papillomavirus infection+++05210///Colorectal cancer+++04921///Oxytocin signaling pathway+++01522///Endocrine resistance+++05213///Endometrial cancer+++05163///Human cytomegalovirus infection+++04928///Parathyroid hormone synthesis, secretion and action+++04072///Phospholipase D signaling pathway+++04151///PI3K-Akt signaling pathway+++04020///Calcium signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05205///Proteoglycans in cancer+++04068///FoxO signaling pathway+++04934///Cushing's syndrome+++04066///HIF-1 signaling pathway+++05215///Prostate cancer+++04510///Focal adhesion+++05230///Central carbon metabolism in cancer+++05219///Bladder cancer+++04015///Rap1 signaling pathway+++04915///Estrogen signaling pathway+++05200///Pathways in cancer+++04520///Adherens junction","H00031///Breast cancer+++H00055///Laryngeal cancer+++H00014///Non-small cell lung cancer+++H00042///Glioma+++H01508///Salivary gland cancer+++H00016///Oral cancer+++H00030///Cervical cancer+++H00028///Choriocarcinoma+++H01559///Oropharyngeal cancer+++H00017///Esophageal cancer+++H00022///Bladder cancer",null,null,"GO:0005634///nucleus+++GO:0070435///Shc-EGFR complex+++GO:0005794///Golgi apparatus+++GO:0097489///multivesicular body, internal vesicle lumen+++GO:0005615///extracellular space+++GO:0030139///endocytic vesicle+++GO:0009925///basal plasma membrane+++GO:0045202///synapse+++GO:0009986///cell surface+++GO:0005768///endosome+++GO:0032991///protein-containing complex+++GO:0031901///early endosome membrane+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005925///focal adhesion+++GO:0010008///endosome membrane+++GO:0045121///membrane raft+++GO:0016323///basolateral plasma membrane+++GO:0031965///nuclear membrane+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0030665///clathrin-coated vesicle membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region","GO:0005178///integrin binding+++GO:0048408///epidermal growth factor binding+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0001618///virus receptor activity+++GO:0000166///nucleotide binding+++GO:0019901///protein kinase binding+++GO:0005006///epidermal growth factor-activated receptor activity+++GO:0005524///ATP binding+++GO:0005516///calmodulin binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0051015///actin filament binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0003682///chromatin binding+++GO:0045296///cadherin binding+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0005102///signaling receptor binding+++GO:0019903///protein phosphatase binding+++GO:0004713///protein tyrosine kinase activity+++GO:0003690///double-stranded DNA binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0046982///protein heterodimerization activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0042802///identical protein binding+++GO:0016740///transferase activity","GO:0007275///multicellular organism development+++GO:0038128///ERBB2 signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071276///cellular response to cadmium ion+++GO:0010960///magnesium ion homeostasis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0014070///response to organic cyclic compound+++GO:0071363///cellular response to growth factor stimulus+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0006898///receptor-mediated endocytosis+++GO:0007611///learning or memory+++GO:0030154///cell differentiation+++GO:0033993///response to lipid+++GO:0071392///cellular response to estradiol stimulus+++GO:0042127///regulation of cell proliferation+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0046718///viral entry into host cell+++GO:0001934///positive regulation of protein phosphorylation+++GO:0061029///eyelid development in camera-type eye+++GO:0060571///morphogenesis of an epithelial fold+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:0009968///negative regulation of signal transduction+++GO:0045907///positive regulation of vasoconstriction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0042060///wound healing+++GO:1905208///negative regulation of cardiocyte differentiation+++GO:0042327///positive regulation of phosphorylation+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0043586///tongue development+++GO:0001892///embryonic placenta development+++GO:0046328///regulation of JNK cascade+++GO:0000165///MAPK cascade+++GO:0030335///positive regulation of cell migration+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0045739///positive regulation of DNA repair+++GO:0045780///positive regulation of bone resorption+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0035556///intracellular signal transduction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0042177///negative regulation of protein catabolic process+++GO:0000186///activation of MAPKK activity+++GO:0007494///midgut development+++GO:0001889///liver development+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0042698///ovulation cycle+++GO:0043006///activation of phospholipase A2 activity by calcium-mediated signaling+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034614///cellular response to reactive oxygen species+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0006979///response to oxidative stress+++GO:0021795///cerebral cortex cell migration+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0007623///circadian rhythm+++GO:2000145///regulation of cell motility+++GO:0071260///cellular response to mechanical stimulus+++GO:0048812///neuron projection morphogenesis+++GO:0048546///digestive tract morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:1900020///positive regulation of protein kinase C activity+++GO:0016101///diterpenoid metabolic process+++GO:0001503///ossification+++GO:0006468///protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:1902722///positive regulation of prolactin secretion+++GO:0098609///cell-cell adhesion+++GO:0008544///epidermis development+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0097421///liver regeneration+++GO:0033590///response to cobalamin+++GO:0030307///positive regulation of cell growth+++GO:0033594///response to hydroxyisoflavone+++GO:0042743///hydrogen peroxide metabolic process+++GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0008283///cell proliferation+++GO:0071230///cellular response to amino acid stimulus+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0010750///positive regulation of nitric oxide mediated signal transduction+++GO:0030324///lung development+++GO:0007166///cell surface receptor signaling pathway+++GO:0000902///cell morphogenesis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0006970///response to osmotic stress+++GO:0016310///phosphorylation+++GO:0050729///positive regulation of inflammatory response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1901185///negative regulation of ERBB signaling pathway+++GO:0006412///translation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045740///positive regulation of DNA replication+++GO:0001942///hair follicle development+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051205///protein insertion into membrane+++GO:0097755///positive regulation of blood vessel diameter+++GO:0032355///response to estradiol+++GO:0051592///response to calcium ion+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0061024///membrane organization+++GO:0070141///response to UV-A+++GO:0048143///astrocyte activation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0007435///salivary gland morphogenesis+++GO:0035690///cellular response to drug","epidermal growth factor receptor","[EGFR_HUMAN|Reviewed]RecName: Full=Epidermal growth factor receptor; EC=2.7.10.1; AltName: Full=Proto-oncogene c-ErbB-1; AltName: Full=Receptor tyrosine-protein kinase erbB-1; Flags: Precursor;+++[A0A068JCC9_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:AIE16170.1}; Flags: Fragment;+++[A0A068JD88_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:AIE16171.1}; Flags: Fragment;+++[A0A1W2PRR9_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|Ensembl:ENSP00000492462};+++[A0A1Y0DMK7_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:ART92273.1}; Flags: Fragment;+++[A2VCQ7_HUMAN|Unreviewed]SubName: Full=EGFR protein {ECO:0000313|EMBL:AAI28420.1}; Flags: Fragment;+++[A7VMV4_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:BAF79636.1}; Flags: Fragment;+++[A7VN05_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:BAF80002.1}; Flags: Fragment;+++[A7VN06_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor tyrosine kinase domain {ECO:0000313|EMBL:ART34945.1}; Flags: Fragment;+++[A7VN07_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:BAF80004.1}; Flags: Fragment;+++[B6RC65_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor variant EX12_14del {ECO:0000313|EMBL:ABQ66237.1}; Flags: Fragment;+++[B6RC66_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor variant EX12_15del {ECO:0000313|EMBL:ABQ66238.1}; Flags: Fragment;+++[B7Z2I3_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00593197}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00593197};+++[C9JYS6_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|Ensembl:ENSP00000413354}; Flags: Fragment;+++[E2I6F5_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor variant {ECO:0000313|EMBL:ADN43066.1}; EC=2.7.10.1 {ECO:0000313|EMBL:ADN43066.1}; Flags: Fragment;+++[E7BSV0_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00593197}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00593197};+++[E9PFD7_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00593197}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00593197};+++[F1JTL6_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:ADY76965.1}; Flags: Fragment;+++[F2YGG7_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00593197}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00593197};+++[G9MC26_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:BAL40868.1}; Flags: Fragment;+++[G9MC81_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:BAL41217.1}; Flags: Fragment;+++[I3WA68_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:AFK93472.1}; Flags: Fragment;+++[I3WA72_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:AFK93476.1}; Flags: Fragment;+++[I3WA73_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:AFK93477.1}; Flags: Fragment;+++[L0R6G1_HUMAN|Unreviewed]SubName: Full=Alternative protein EGFR {ECO:0000313|EMBL:CCO13722.1};+++[Q147T7_HUMAN|Unreviewed]SubName: Full=EGFR protein {ECO:0000313|EMBL:AAI18666.1};+++[Q30BI0_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:ABB36657.1}; Flags: Fragment;+++[Q4H1F3_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:BAE15958.1}; Flags: Fragment;+++[Q504U8_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00593197}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00593197};+++[Q68GS6_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:AAT97978.1}; Flags: Fragment;+++[Q75MF2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein EGFR {ECO:0000313|EMBL:AAS07524.1}; Flags: Fragment;+++[Q8NDU8_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor {ECO:0000313|EMBL:CAA34902.2};+++[Q8WZA5_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor {ECO:0000313|EMBL:AAC50803.1}; Flags: Fragment;+++[Q9H3C8_HUMAN|Unreviewed]SubName: Full=Truncated epidermal growth factor receptor {ECO:0000313|EMBL:AAG43244.1}; Flags: Fragment;+++[Q9H3D0_HUMAN|Unreviewed]SubName: Full=A431-specific truncated epidermal growth factor receptor {ECO:0000313|EMBL:AAG43245.1}; Flags: Fragment;"]
[196394,"'AMN1'",151.91,151.07,143.25,148.743333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0019005///SCF ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity","GO:0016567///protein ubiquitination+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process","antagonist of mitotic exit network 1 homolog","[AMN1_HUMAN|Reviewed]RecName: Full=Protein AMN1 homolog;+++[E9PHB0_HUMAN|Unreviewed]SubName: Full=Protein AMN1 homolog {ECO:0000313|Ensembl:ENSP00000396145}; Flags: Fragment;+++[F5GWF7_HUMAN|Unreviewed]SubName: Full=Protein AMN1 homolog {ECO:0000313|Ensembl:ENSP00000441846}; Flags: Fragment;+++[F5H1R2_HUMAN|Unreviewed]SubName: Full=Protein AMN1 homolog {ECO:0000313|Ensembl:ENSP00000438990}; Flags: Fragment;+++[F5H286_HUMAN|Unreviewed]SubName: Full=Protein AMN1 homolog {ECO:0000313|Ensembl:ENSP00000439438}; Flags: Fragment;+++[F5H3D1_HUMAN|Unreviewed]SubName: Full=Protein AMN1 homolog {ECO:0000313|Ensembl:ENSP00000439171};+++[F5H7U5_HUMAN|Unreviewed]SubName: Full=Protein AMN1 homolog {ECO:0000313|Ensembl:ENSP00000442272};"]
[196740,"'VSTM4'",188.91,203.47,210.42,200.933333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","V-set and transmembrane domain containing 4","[VSTM4_HUMAN|Reviewed]RecName: Full=V-set and transmembrane domain-containing protein 4; Contains: RecName: Full=Peptide Lv; Flags: Precursor;"]
[197335,"'WDR90'",337,366,351,351.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0060271///cilium assembly+++GO:0030030///cell projection organization","WD repeat domain 90","[WDR90_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 90;+++[F8VUX9_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 90 {ECO:0000313|Ensembl:ENSP00000448122};+++[G3V201_HUMAN|Unreviewed]SubName: Full=HCG1985539, isoform CRA_e {ECO:0000313|EMBL:EAW85773.1}; SubName: Full=WD repeat-containing protein 90 {ECO:0000313|Ensembl:ENSP00000449576};+++[H0YHN4_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 90 {ECO:0000313|Ensembl:ENSP00000447435}; Flags: Fragment;+++[H0YHV6_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 90 {ECO:0000313|Ensembl:ENSP00000447915}; Flags: Fragment;+++[H0YI59_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 90 {ECO:0000313|Ensembl:ENSP00000448603}; Flags: Fragment;+++[H0YIW5_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 90 {ECO:0000313|Ensembl:ENSP00000450308}; Flags: Fragment;"]
[198437,"'LKAAEAR1'",4,4,3,3.66666666666667,{"$nulls":7},"LKAAEAR motif containing 1","[LKAM1_HUMAN|Reviewed]RecName: Full=Protein LKAAEAR1; AltName: Full=LKAAEAR motif-containing protein 1;"]
[199800,"'ADM5'",6,7,8,7,{"$nulls":4},"GO:0005575///cellular_component+++GO:0005576///extracellular region","GO:0003674///molecular_function","GO:0008150///biological_process","adrenomedullin 5 (putative)","[ADM5_HUMAN|Reviewed]RecName: Full=Putative adrenomedullin-5-like protein; Flags: Precursor;"]
[200030,"'NBPF11'",291.35,389.58,260.19,313.706666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++00062///Fatty acid elongation",null,null,"R01274///palmitoyl-CoA hydrolase Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid","GO:0005737///cytoplasm","GO:0008474///palmitoyl-(protein) hydrolase activity","GO:1905668///positive regulation of protein localization to endosome+++GO:1902817///negative regulation of protein localization to microtubule+++GO:0072657///protein localization to membrane+++GO:0099175///regulation of postsynapse organization+++GO:0018345///protein palmitoylation+++GO:0002084///protein depalmitoylation","NBPF member 11","[NBPFB_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000305}; AltName: Full=Neuroblastoma breakpoint family member 24 {ECO:0000312|HGNC:HGNC:31993};+++[A0A087WTH4_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000313|Ensembl:ENSP00000477874}; Flags: Fragment;+++[A0A087WUF5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000313|Ensembl:ENSP00000478618};+++[A0A087WVG8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000313|Ensembl:ENSP00000479429};+++[L8ECP6_HUMAN|Unreviewed]SubName: Full=Alternative protein NBPF11 {ECO:0000313|EMBL:CCQ43932.1};"]
[200407,"'CREG2'",9,4,4,5.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum","GO:0048037///cofactor binding",null,"cellular repressor of E1A stimulated genes 2","[CREG2_HUMAN|Reviewed]RecName: Full=Protein CREG2; Flags: Precursor;+++[Q4ZFW3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CREG2 {ECO:0000313|EMBL:AAX88886.1}; Flags: Fragment;+++[Q580X0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CREG2 {ECO:0000313|EMBL:AAX82005.1}; Flags: Fragment;"]
[200942,"'KLHDC8B'",1096,1250,1071,1139,{"$nulls":4},"GO:0030496///midbody+++GO:0110070///cellularization cleavage furrow+++GO:0045171///intercellular bridge+++GO:0005829///cytosol+++GO:0005737///cytoplasm",null,"GO:1902410///mitotic cytokinetic process+++GO:0140014///mitotic nuclear division+++GO:0051301///cell division+++GO:0098813///nuclear chromosome segregation+++GO:0007049///cell cycle","kelch domain containing 8B","[KLD8B_HUMAN|Reviewed]RecName: Full=Kelch domain-containing protein 8B {ECO:0000303|PubMed:19706467};+++[A0A024R2X4_HUMAN|Unreviewed]SubName: Full=Kelch domain containing 8B, isoform CRA_b {ECO:0000313|EMBL:EAW64963.1};+++[Q96DZ8_HUMAN|Unreviewed]SubName: Full=KLHDC8B protein {ECO:0000313|EMBL:AAH13110.2}; Flags: Fragment;"]
[201181,"'ZNF385C'",8,1,2,3.66666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator","zinc finger protein 385C","[Z385C_HUMAN|Reviewed]RecName: Full=Zinc finger protein 385C {ECO:0000312|HGNC:HGNC:33722};+++[C9J6X6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385C {ECO:0000313|Ensembl:ENSP00000411514};"]
[201255,"'LRRC45'",268,268,219,251.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding",null,"leucine rich repeat containing 45","[LRC45_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 45;+++[J3KTD4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 45 {ECO:0000313|Ensembl:ENSP00000462928}; Flags: Fragment;"]
[201931,"'TMEM192'",378,407.84,348,377.946666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005770///late endosome+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0042803///protein homodimerization activity",null,"transmembrane protein 192","[TM192_HUMAN|Reviewed]RecName: Full=Transmembrane protein 192;+++[D6RAZ6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 192 {ECO:0000313|Ensembl:ENSP00000424590}; Flags: Fragment;"]
[202500,"'TCTE1'",7,7,1,5,{"$nulls":4},"GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0005856///cytoskeleton+++GO:0031514///motile cilium+++GO:0005737///cytoplasm",null,"GO:0030317///flagellated sperm motility","t-complex-associated-testis-expressed 1","[DRC5_HUMAN|Reviewed]RecName: Full=Dynein regulatory complex subunit 5 {ECO:0000250|UniProtKB:A6H639}; AltName: Full=T-complex-associated testis-expressed protein 1; Short=Tcte-1;+++[Q5JU01_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex subunit 5 {ECO:0000313|Ensembl:ENSP00000360559};"]
[203,"'AK1'",821,910.16,787.13,839.43,"01130///Biosynthesis of antibiotics+++00730///Thiamine metabolism+++00230///Purine metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00092///T-B-Severe combined immunodeficiencies (SCIDs)+++H01128///Reticular dysgenesis+++H00674///Anemia due to disorders of nucleotide metabolism","M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R01547///ATP:dAMP phosphotransferase   ATP + dAMP <=> ADP + dADP+++R00127///ATP:AMP phosphotransferase   ATP + AMP <=> 2 ADP+++R11319///ADP:thiamin-diphosphate phosphotransferase   Thiamin diphosphate + ADP <=> Thiamin triphosphate + AMP","GO:0005829///cytosol+++GO:0036126///sperm flagellum+++GO:0005886///plasma membrane+++GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0016740///transferase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0004017///adenylate kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0019205///nucleobase-containing compound kinase activity","GO:0046940///nucleoside monophosphate phosphorylation+++GO:0046033///AMP metabolic process+++GO:0016310///phosphorylation+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0046034///ATP metabolic process+++GO:0006172///ADP biosynthetic process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0007050///cell cycle arrest+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0006165///nucleoside diphosphate phosphorylation","adenylate kinase 1","[KAD1_HUMAN|Reviewed]RecName: Full=Adenylate kinase isoenzyme 1 {ECO:0000255|HAMAP-Rule:MF_03171}; Short=AK 1 {ECO:0000255|HAMAP-Rule:MF_03171}; EC=2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03171}; EC=2.7.4.6 {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=ATP-AMP transphosphorylase 1 {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=Myokinase {ECO:0000255|HAMAP-Rule:MF_03171};+++[F8VRY5_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 1 {ECO:0000313|Ensembl:ENSP00000448741};+++[H0YID2_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 1 {ECO:0000313|Ensembl:ENSP00000449130}; Flags: Fragment;+++[Q5T9B7_HUMAN|Unreviewed]RecName: Full=Adenylate kinase isoenzyme 1 {ECO:0000256|HAMAP-Rule:MF_03171}; Short=AK 1 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.3 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.6 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP-AMP transphosphorylase 1 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Adenylate monophosphate kinase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Myokinase {ECO:0000256|HAMAP-Rule:MF_03171};+++[Q6FGX9_HUMAN|Unreviewed]RecName: Full=Adenylate kinase isoenzyme 1 {ECO:0000256|HAMAP-Rule:MF_03171}; Short=AK 1 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.3 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.6 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP-AMP transphosphorylase 1 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Adenylate monophosphate kinase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Myokinase {ECO:0000256|HAMAP-Rule:MF_03171};"]
[203522,"'INTS6L'",88,115,113,105.333333333333,{"$nulls":4},"GO:0032039///integrator complex",null,"GO:0034472///snRNA 3'-end processing","integrator complex subunit 6 like","[INT6L_HUMAN|Reviewed]RecName: Full=Integrator complex subunit 6-like; AltName: Full=Protein DDX26B;+++[A0A1W2PPI5_HUMAN|Unreviewed]SubName: Full=DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B, isoform CRA_b {ECO:0000313|EMBL:EAX11726.1}; SubName: Full=Integrator complex subunit 6-like {ECO:0000313|Ensembl:ENSP00000491427};+++[B9EIK3_HUMAN|Unreviewed]SubName: Full=DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B {ECO:0000313|EMBL:AAI40716.1};+++[Q8N8M2_HUMAN|Unreviewed]SubName: Full=DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B, isoform CRA_c {ECO:0000313|EMBL:EAX11727.1}; SubName: Full=cDNA FLJ39225 fis, clone OCBBF2007224, highly similar to Homo sapiens candidate tumor suppressor protein DICE1 mRNA {ECO:0000313|EMBL:BAC04813.1};"]
[204,"'AK2'",1592,1654,1572,1606,"01100///Metabolic pathways+++00230///Purine metabolism+++01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites+++00730///Thiamine metabolism","H00092///T-B-Severe combined immunodeficiencies (SCIDs)+++H01128///Reticular dysgenesis+++H00674///Anemia due to disorders of nucleotide metabolism","M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R01547///ATP:dAMP phosphotransferase   ATP + dAMP <=> ADP + dADP+++R11319///ADP:thiamin-diphosphate phosphotransferase   Thiamin diphosphate + ADP <=> Thiamin triphosphate + AMP+++R00127///ATP:AMP phosphotransferase   ATP + AMP <=> 2 ADP","GO:0070062///extracellular exosome+++GO:0005739///mitochondrion+++GO:0097226///sperm mitochondrial sheath+++GO:0036126///sperm flagellum+++GO:0005758///mitochondrial intermembrane space","GO:0004017///adenylate kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016776///phosphotransferase activity, phosphate group as acceptor+++GO:0000166///nucleotide binding+++GO:0019205///nucleobase-containing compound kinase activity","GO:0006139///nucleobase-containing compound metabolic process+++GO:0046033///AMP metabolic process+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0046034///ATP metabolic process+++GO:0006172///ADP biosynthetic process+++GO:0016310///phosphorylation","adenylate kinase 2","[KAD2_HUMAN|Reviewed]RecName: Full=Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}; Short=AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}; EC=2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03168}; AltName: Full=ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}; AltName: Full=Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}; Contains: RecName: Full=Adenylate kinase 2, mitochondrial, N-terminally processed {ECO:0000255|HAMAP-Rule:MF_03168};+++[A0A140VK93_HUMAN|Unreviewed]RecName: Full=Adenylate kinase 2, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03168}; Short=AK 2 {ECO:0000256|HAMAP-Rule:MF_03168}; EC=2.7.4.3 {ECO:0000256|HAMAP-Rule:MF_03168}; AltName: Full=ATP-AMP transphosphorylase 2 {ECO:0000256|HAMAP-Rule:MF_03168}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000256|HAMAP-Rule:MF_03168}; AltName: Full=Adenylate monophosphate kinase {ECO:0000256|HAMAP-Rule:MF_03168};+++[F8VPP1_HUMAN|Unreviewed]SubName: Full=Adenylate kinase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000450008};+++[F8VY04_HUMAN|Unreviewed]SubName: Full=Adenylate kinase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000449003};+++[F8VZG5_HUMAN|Unreviewed]SubName: Full=Adenylate kinase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000446849};+++[F8W1A4_HUMAN|Unreviewed]RecName: Full=Adenylate kinase 2, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03168}; Short=AK 2 {ECO:0000256|HAMAP-Rule:MF_03168}; EC=2.7.4.3 {ECO:0000256|HAMAP-Rule:MF_03168}; AltName: Full=ATP-AMP transphosphorylase 2 {ECO:0000256|HAMAP-Rule:MF_03168}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000256|HAMAP-Rule:MF_03168}; AltName: Full=Adenylate monophosphate kinase {ECO:0000256|HAMAP-Rule:MF_03168};+++[G3V213_HUMAN|Unreviewed]SubName: Full=Adenylate kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAX07483.1}; SubName: Full=Adenylate kinase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000450109};"]
[2055,"'CLN8'",377,344.01,356,359.003333333333,null,"H00149///Neuronal ceroid lipofuscinosis (NCL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0098793///presynapse+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment",null,"GO:0060052///neurofilament cytoskeleton organization+++GO:0007006///mitochondrial membrane organization+++GO:0035176///social behavior+++GO:0006672///ceramide metabolic process+++GO:0044257///cellular protein catabolic process+++GO:0008203///cholesterol metabolic process+++GO:0050884///neuromuscular process controlling posture+++GO:0044265///cellular macromolecule catabolic process+++GO:0008306///associative learning+++GO:0001306///age-dependent response to oxidative stress+++GO:0043066///negative regulation of apoptotic process+++GO:0008610///lipid biosynthetic process+++GO:0007628///adult walking behavior+++GO:0050881///musculoskeletal movement+++GO:0006869///lipid transport+++GO:0060041///retina development in camera-type eye+++GO:0050885///neuromuscular process controlling balance+++GO:0007399///nervous system development+++GO:0046513///ceramide biosynthetic process+++GO:0007040///lysosome organization+++GO:0021523///somatic motor neuron differentiation+++GO:0045494///photoreceptor cell maintenance+++GO:0008361///regulation of cell size+++GO:0021522///spinal cord motor neuron differentiation+++GO:0030163///protein catabolic process+++GO:0045861///negative regulation of proteolysis+++GO:0044267///cellular protein metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0051935///glutamate reuptake+++GO:0008344///adult locomotory behavior+++GO:0007601///visual perception","CLN8, transmembrane ER and ERGIC protein","[CLN8_HUMAN|Reviewed]RecName: Full=Protein CLN8;+++[A0A024QZ57_HUMAN|Unreviewed]SubName: Full=Ceroid-lipofuscinosis, neuronal 8 (Epilepsy, progressive with mental retardation), isoform CRA_a {ECO:0000313|EMBL:EAW51478.1};+++[A0A0J9YWD2_HUMAN|Unreviewed]SubName: Full=Protein CLN8 {ECO:0000313|Ensembl:ENSP00000487905};+++[A0A0J9YX19_HUMAN|Unreviewed]SubName: Full=Protein CLN8 {ECO:0000313|Ensembl:ENSP00000488211}; Flags: Fragment;+++[A0A0J9YXY6_HUMAN|Unreviewed]SubName: Full=Protein CLN8 {ECO:0000313|Ensembl:ENSP00000488606}; Flags: Fragment;+++[A0A0J9YYK8_HUMAN|Unreviewed]SubName: Full=Protein CLN8 {ECO:0000313|Ensembl:ENSP00000488898}; Flags: Fragment;+++[A0A1B0GU79_HUMAN|Unreviewed]SubName: Full=Protein CLN8 {ECO:0000313|Ensembl:ENSP00000489999}; Flags: Fragment;+++[A0A1B0GUR8_HUMAN|Unreviewed]SubName: Full=Protein CLN8 {ECO:0000313|Ensembl:ENSP00000490218};+++[B9EGV9_HUMAN|Unreviewed]SubName: Full=Ceroid-lipofuscinosis, neuronal 8 (Epilepsy, progressive with mental retardation) {ECO:0000313|EMBL:AAI36826.1};"]
[2066,"'ERBB4'",730,746,552,676,"05205///Proteoglycans in cancer+++04151///PI3K-Akt signaling pathway+++04012///ErbB signaling pathway+++04010///MAPK signaling pathway+++04020///Calcium signaling pathway","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0016323///basolateral plasma membrane+++GO:0005634///nucleus+++GO:0098982///GABA-ergic synapse+++GO:0045211///postsynaptic membrane+++GO:0043235///receptor complex+++GO:0099056///integral component of presynaptic membrane+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0009925///basal plasma membrane+++GO:0005829///cytosol","GO:0004888///transmembrane signaling receptor activity+++GO:0000166///nucleotide binding+++GO:0042803///protein homodimerization activity+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding","GO:0008285///negative regulation of cell proliferation+++GO:0007275///multicellular organism development+++GO:0009968///negative regulation of signal transduction+++GO:0046777///protein autophosphorylation+++GO:0009880///embryonic pattern specification+++GO:0008284///positive regulation of cell proliferation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0061026///cardiac muscle tissue regeneration+++GO:0045165///cell fate commitment+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0006915///apoptotic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007399///nervous system development+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0021551///central nervous system morphogenesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0007595///lactation+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0000165///MAPK cascade+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0016310///phosphorylation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0007416///synapse assembly+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0007507///heart development+++GO:0060749///mammary gland alveolus development+++GO:0006468///protein phosphorylation+++GO:0001755///neural crest cell migration+++GO:2000145///regulation of cell motility+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0030334///regulation of cell migration+++GO:0051897///positive regulation of protein kinase B signaling+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0021889///olfactory bulb interneuron differentiation+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0038128///ERBB2 signaling pathway+++GO:2001223///negative regulation of neuron migration+++GO:0016477///cell migration+++GO:0007165///signal transduction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway","erb-b2 receptor tyrosine kinase 4","[ERBB4_HUMAN|Reviewed]RecName: Full=Receptor tyrosine-protein kinase erbB-4; EC=2.7.10.1; AltName: Full=Proto-oncogene-like protein c-ErbB-4; AltName: Full=Tyrosine kinase-type cell surface receptor HER4; AltName: Full=p180erbB4; Contains: RecName: Full=ERBB4 intracellular domain; Short=4ICD; Short=E4ICD; AltName: Full=s80HER4; Flags: Precursor;+++[A0A0A0MSE1_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00593197}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00593197};+++[A0A0P0I3A3_HUMAN|Unreviewed]SubName: Full=ERBB4 transcript variant I20DEL {ECO:0000313|EMBL:ALJ93279.1};+++[A0A0P0IT07_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00593197}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00593197};+++[E9PDR1_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-4 {ECO:0000313|Ensembl:ENSP00000405564}; Flags: Fragment;+++[H3BLT0_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-4 {ECO:0000313|Ensembl:ENSP00000260943}; Flags: Fragment;+++[L8E872_HUMAN|Unreviewed]SubName: Full=Alternative protein ERBB4 {ECO:0000313|EMBL:CCQ43309.1};+++[Q4ZG14_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ERBB4 {ECO:0000313|EMBL:AAX88856.1}; Flags: Fragment;+++[Q53QS8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ERBB4 {ECO:0000313|EMBL:AAY24303.1}; Flags: Fragment;+++[Q53R25_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ERBB4 {ECO:0000313|EMBL:AAY24158.1}; Flags: Fragment;+++[Q53R48_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ERBB4 {ECO:0000313|EMBL:AAY14899.1}; Flags: Fragment;+++[Q53T57_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ERBB4 {ECO:0000313|EMBL:AAY15092.1}; Flags: Fragment;+++[Q580Q7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ERBB4 {ECO:0000313|EMBL:AAX82011.1}; Flags: Fragment;"]
[2078,"'ERG'",21,22,12,18.3333333333333,"05215///Prostate cancer+++05202///Transcriptional misregulation in cancer","H00024///Prostate cancer+++H00035///Ewing's sarcoma",null,null,"GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0006468///protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction","ETS transcription factor ERG","[ERG_HUMAN|Reviewed]RecName: Full=Transcriptional regulator ERG; AltName: Full=Transforming protein ERG;+++[A0A088AWP2_HUMAN|Unreviewed]SubName: Full=Transcriptional regulator ERG {ECO:0000313|Ensembl:ENSP00000415659};+++[A0A0C4DG41_HUMAN|Unreviewed]SubName: Full=Transcriptional regulator ERG {ECO:0000313|Ensembl:ENSP00000396268};+++[A8MX39_HUMAN|Unreviewed]SubName: Full=Transcriptional regulator ERG {ECO:0000313|Ensembl:ENSP00000381879};+++[A8MZ24_HUMAN|Unreviewed]SubName: Full=Transcriptional regulator ERG {ECO:0000313|Ensembl:ENSP00000381881};+++[B2Y833_HUMAN|Unreviewed]SubName: Full=TMPRSS2-ERG prostate cancer specific isoform 1 {ECO:0000313|EMBL:ACA81385.1};+++[B4DN83_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60726, highly similar to Transcriptional regulator ERG {ECO:0000313|EMBL:BAG60145.1};+++[B4DVX5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52282, highly similar to Transcriptional regulator ERG {ECO:0000313|EMBL:BAG62837.1};+++[B5MDW0_HUMAN|Unreviewed]SubName: Full=Erythroblast transformation-specific transcription factor ERG variant 10 {ECO:0000313|EMBL:AJT59682.1}; SubName: Full=Transcriptional regulator ERG {ECO:0000313|Ensembl:ENSP00000381877};"]
[2115,"'ETV1'",107,117,88,104,"05202///Transcriptional misregulation in cancer","H00035///Ewing's sarcoma+++H00024///Prostate cancer",null,null,"GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007638///mechanosensory behavior+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0007517///muscle organ development+++GO:0007411///axon guidance+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048935///peripheral nervous system neuron development","ETS variant 1","[ETV1_HUMAN|Reviewed]RecName: Full=ETS translocation variant 1; AltName: Full=Ets-related protein 81;+++[A0A024R9Z3_HUMAN|Unreviewed]SubName: Full=Ets variant gene 1, isoform CRA_a {ECO:0000313|EMBL:EAW93657.1};+++[A0A024R9Z5_HUMAN|Unreviewed]SubName: Full=Ets variant gene 1, isoform CRA_d {ECO:0000313|EMBL:EAW93662.1};+++[A0A024RA02_HUMAN|Unreviewed]SubName: Full=Ets variant gene 1, isoform CRA_e {ECO:0000313|EMBL:EAW93661.1};+++[B5MCT2_HUMAN|Unreviewed]SubName: Full=ETS translocation variant 1 {ECO:0000313|Ensembl:ENSP00000384085};+++[B7Z2C9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50494, highly similar to ETS translocation variant 1 {ECO:0000313|EMBL:BAH11815.1};+++[C9J0B7_HUMAN|Unreviewed]SubName: Full=ETS translocation variant 1 {ECO:0000313|Ensembl:ENSP00000406931}; Flags: Fragment;+++[C9J4P4_HUMAN|Unreviewed]SubName: Full=ETS translocation variant 1 {ECO:0000313|Ensembl:ENSP00000391043}; Flags: Fragment;+++[C9J9L1_HUMAN|Unreviewed]SubName: Full=ETS translocation variant 1 {ECO:0000313|Ensembl:ENSP00000410819}; Flags: Fragment;+++[C9JQH6_HUMAN|Unreviewed]SubName: Full=ETS translocation variant 1 {ECO:0000313|Ensembl:ENSP00000394710}; Flags: Fragment;+++[C9JX69_HUMAN|Unreviewed]SubName: Full=ETS translocation variant 1 {ECO:0000313|Ensembl:ENSP00000393078}; Flags: Fragment;+++[F8WEH6_HUMAN|Unreviewed]SubName: Full=ETS translocation variant 1 {ECO:0000313|Ensembl:ENSP00000413836};"]
[2134,"'EXTL1'",47,55,36,46,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin+++01100///Metabolic pathways",null,"M00059///Glycosaminoglycan biosynthesis, heparan sulfate backbone","R05936///UDP-N-acetyl-D-glucosamine + G00163 <=> UDP + G00164","GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0016740///transferase activity+++GO:0050508///glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0006486///protein glycosylation+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001501///skeletal system development","exostosin like glycosyltransferase 1","[EXTL1_HUMAN|Reviewed]RecName: Full=Exostosin-like 1; EC=2.4.1.224; AltName: Full=Exostosin-L; AltName: Full=Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; AltName: Full=Multiple exostosis-like protein;"]
[214,"'ALCAM'",4148,3155,3314,3539,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0009897///external side of plasma membrane+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0042101///T cell receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0001772///immunological synapse+++GO:0005925///focal adhesion","GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0002250///adaptive immune response+++GO:0008045///motor neuron axon guidance+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0031290///retinal ganglion cell axon guidance+++GO:0007411///axon guidance+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0048846///axon extension involved in axon guidance+++GO:1990138///neuron projection extension","activated leukocyte cell adhesion molecule","[CD166_HUMAN|Reviewed]RecName: Full=CD166 antigen; AltName: Full=Activated leukocyte cell adhesion molecule; AltName: CD_antigen=CD166; Flags: Precursor;+++[B3KNN9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30070 fis, clone ASTRO2000046, highly similar to CD166 ANTIGEN {ECO:0000313|EMBL:BAG51401.1};+++[F5GXJ9_HUMAN|Unreviewed]SubName: Full=CD166 antigen {ECO:0000313|Ensembl:ENSP00000418213};+++[H7C543_HUMAN|Unreviewed]SubName: Full=CD166 antigen {ECO:0000313|Ensembl:ENSP00000418937}; Flags: Fragment;"]
[2160,"'F11'",1,0,0,0.333333333333333,"04610///Complement and coagulation cascades","H00938///Factor XI deficiency",null,null,"GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0070009///serine-type aminopeptidase activity+++GO:0042802///identical protein binding+++GO:0008201///heparin binding+++GO:0004252///serine-type endopeptidase activity","GO:0007597///blood coagulation, intrinsic pathway+++GO:0007596///blood coagulation+++GO:0051919///positive regulation of fibrinolysis+++GO:0031639///plasminogen activation","coagulation factor XI","[FA11_HUMAN|Reviewed]RecName: Full=Coagulation factor XI; Short=FXI; EC=3.4.21.27; AltName: Full=Plasma thromboplastin antecedent; Short=PTA; Contains: RecName: Full=Coagulation factor XIa heavy chain; Contains: RecName: Full=Coagulation factor XIa light chain; Flags: Precursor;"]
[2193,"'FARSA'",1498,1521,1399,1472.66666666667,"00970///Aminoacyl-tRNA biosynthesis","H00891///Combined oxidative phosphorylation deficiency (COXPD)+++H00266///Hereditary spastic paraplegia (SPG)","M00360///Aminoacyl-tRNA biosynthesis, prokaryotes+++M00359///Aminoacyl-tRNA biosynthesis, eukaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009328///phenylalanine-tRNA ligase complex+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004826///phenylalanine-tRNA ligase activity+++GO:0000049///tRNA binding+++GO:0016874///ligase activity","GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0006412///translation+++GO:0051290///protein heterotetramerization","phenylalanyl-tRNA synthetase subunit alpha","[SYFA_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase alpha subunit; EC=6.1.1.20 {ECO:0000269|PubMed:20223217}; AltName: Full=CML33; AltName: Full=Phenylalanyl-tRNA synthetase alpha subunit; Short=PheRS;+++[K7EK06_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000465402}; Flags: Fragment;+++[K7EPH2_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000467384}; Flags: Fragment;+++[K7ER00_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000468051};+++[K7ER16_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000468068};+++[K7ERS0_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000468384}; Flags: Fragment;+++[Q6IBR2_HUMAN|Unreviewed]SubName: Full=FARSLA protein {ECO:0000313|EMBL:CAG33021.1}; SubName: Full=Phenylalanine-tRNA synthetase-like, alpha subunit, isoform CRA_b {ECO:0000313|EMBL:EAW84329.1}; SubName: Full=cDNA FLJ34774 fis, clone NT2NE2003309, highly similar to Phenylalanyl-tRNA synthetase alpha chain {ECO:0000313|EMBL:BAG52481.1};"]
[2194,"'FASN'",8574,10997,10022,9864.33333333333,"04910///Insulin signaling pathway+++01212///Fatty acid metabolism+++04152///AMPK signaling pathway+++01100///Metabolic pathways+++00061///Fatty acid biosynthesis",null,"M00082///Fatty acid biosynthesis, initiation+++M00083///Fatty acid biosynthesis, elongation","R04544///(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase   (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] <=> trans-Hexadec-2-enoyl-[acp] + H2O+++R04968///Tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexadecanoyl-[acp] + CO2 + Acyl-carrier protein+++R04726///dodecanoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Dodecanoyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CO2 + Acyl-carrier protein+++R04537///(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase; (3R)-3-Hydroxyoctanoyl-[acyl-carrier-protein]   (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <=> trans-Oct-2-enoyl-[acp] + H2O+++R04970///hexadecanoyl-[acp]:NADP+ trans-2-oxidoreductase   Hexadecanoyl-[acp] + NADP+ <=> trans-Hexadec-2-enoyl-[acp] + NADPH + H++++R01404///acyl-[acyl-carrier protein]:NADP+ oxidoreductase   Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H++++R04355///Acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CO2 + Acyl-carrier protein+++R01706///hexadecanoyl-[acyl-carrier protein] hydrolase   Hexadecanoyl-[acp] + H2O <=> Acyl-carrier protein + Hexadecanoic acid+++R04536///(3R)-3-Hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase   (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H++++R01624///acetyl-CoA:[acyl-carrier-protein] S-acetyltransferase   Acetyl-CoA + Acyl-carrier protein <=> CoA + Acetyl-[acyl-carrier protein]+++R01626///Malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase   Malonyl-CoA + Acyl-carrier protein <=> CoA + Malonyl-[acyl-carrier protein]+++R04952///butyryl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Butyryl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexanoyl-[acp] + CO2 + Acyl-carrier protein+++R04566///(3R)-3-Hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase   (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H++++R04953///(3R)-3-Hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase   (R)-3-Hydroxyhexanoyl-[acp] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H++++R04954///(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase   (R)-3-Hydroxyhexanoyl-[acp] <=> trans-Hex-2-enoyl-[acp] + H2O+++R04959///octanoyl-[acp]:NADP+ trans-2-oxidoreductase   Octanoyl-[acp] + NADP+ <=> trans-Oct-2-enoyl-[acp] + NADPH + H++++R04428///(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase   (3R)-3-Hydroxybutanoyl-[acyl-carrier protein] <=> But-2-enoyl-[acyl-carrier protein] + H2O+++R04535///(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase   (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=> trans-Dec-2-enoyl-[acp] + H2O+++R04963///Decanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Decanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxododecanoyl-[acp] + CO2 + Acyl-carrier protein+++R04956///hexanoyl-[acp]:NADP+ trans-2-oxidoreductase   Hexanoyl-[acp] + NADP+ <=> trans-Hex-2-enoyl-[acp] + NADPH + H++++R04543///(3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase   (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H++++R04962///decanoyl-[acp]:NADP+ trans-2-oxidoreductase   Decanoyl-[acp] + NADP+ <=> trans-Dec-2-enoyl-[acp] + NADPH + H++++R04957///hexanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxooctanoyl-[acp] + CO2 + Acyl-carrier protein+++R04725///dodecanoyl-[acp]:NADP+ trans-2-oxidoreductase   Dodecanoyl-[acyl-carrier protein] + NADP+ <=> trans-Dodec-2-enoyl-[acp] + NADPH + H++++R04960///Octanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Octanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CO2 + Acyl-carrier protein+++R04533///(3R)-3-Hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase   (3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H++++R04967///tetradecanoyl-[acp]:NADP+ trans-2-oxidoreductase   Tetradecanoyl-[acp] + NADP+ <=> trans-Tetradec-2-enoyl-[acp] + NADPH + H++++R04568///(3R)-3-Hydroxypalmitoyl-[acyl-carrier-protein] hydro-lyase   (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=> trans-Tetradec-2-enoyl-[acp] + H2O+++R04965///(3R)-3-Hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase   (R)-3-Hydroxydodecanoyl-[acp] <=> trans-Dodec-2-enoyl-[acp] + H2O+++R04430///butyryl-[acp]:NADP+ trans-2-oxidoreductase   Butyryl-[acp] + NADP+ <=> But-2-enoyl-[acyl-carrier protein] + NADPH + H++++R08159///tetradecanoyl-[acyl-carrier protein] hydrolase   Tetradecanoyl-[acp] + H2O <=> Acyl-carrier protein + Tetradecanoic acid+++R04534///(3R)-3-Hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase   (3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH","GO:0031265///CD95 death-inducing signaling complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042470///melanosome+++GO:0031264///death-inducing signaling complex+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0042587///glycogen granule+++GO:0016604///nuclear body+++GO:0005794///Golgi apparatus+++GO:0045121///membrane raft+++GO:0009986///cell surface+++GO:0005886///plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0016295///myristoyl-[acyl-carrier-protein] hydrolase activity+++GO:0019171///3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity+++GO:0016296///palmitoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016829///lyase activity+++GO:0070402///NADPH binding+++GO:0003824///catalytic activity+++GO:0004316///3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity+++GO:0102131///3-oxo-glutaryl-[acp] methyl ester reductase activity+++GO:0031177///phosphopantetheine binding+++GO:0004314///[acyl-carrier-protein] S-malonyltransferase activity+++GO:0042802///identical protein binding+++GO:0008659///(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity+++GO:0004315///3-oxoacyl-[acyl-carrier-protein] synthase activity+++GO:0047451///3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity+++GO:0004312///fatty acid synthase activity+++GO:0016419///S-malonyltransferase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0004320///oleoyl-[acyl-carrier-protein] hydrolase activity+++GO:0047117///enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity+++GO:0045296///cadherin binding+++GO:0016418///S-acetyltransferase activity+++GO:0008144///drug binding+++GO:0004313///[acyl-carrier-protein] S-acetyltransferase activity+++GO:0019900///kinase binding+++GO:0003723///RNA binding+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0038023///signaling receptor activity+++GO:0016740///transferase activity+++GO:0102132///3-oxo-pimeloyl-[acp] methyl ester reductase activity+++GO:0005516///calmodulin binding+++GO:0016297///acyl-[acyl-carrier-protein] hydrolase activity","GO:0006629///lipid metabolic process+++GO:0097527///necroptotic signaling pathway+++GO:0009888///tissue development+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0006633///fatty acid biosynthetic process+++GO:0048468///cell development+++GO:0046949///fatty-acyl-CoA biosynthetic process+++GO:0065003///protein-containing complex assembly+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0097190///apoptotic signaling pathway+++GO:0043170///macromolecule metabolic process+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0030879///mammary gland development+++GO:0006955///immune response+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:0034198///cellular response to amino acid starvation+++GO:0055114///oxidation-reduction process+++GO:0071353///cellular response to interleukin-4+++GO:0043066///negative regulation of apoptotic process+++GO:0031325///positive regulation of cellular metabolic process+++GO:0007165///signal transduction+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001649///osteoblast differentiation+++GO:0071455///cellular response to hyperoxia+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0030223///neutrophil differentiation+++GO:0006915///apoptotic process+++GO:0008611///ether lipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0006084///acetyl-CoA metabolic process+++GO:0036337///Fas signaling pathway+++GO:0008152///metabolic process+++GO:0030224///monocyte differentiation","fatty acid synthase","[FAS_HUMAN|Reviewed]RecName: Full=Fatty acid synthase; EC=2.3.1.85; Includes: RecName: Full=[Acyl-carrier-protein] S-acetyltransferase; EC=2.3.1.38; Includes: RecName: Full=[Acyl-carrier-protein] S-malonyltransferase; EC=2.3.1.39; Includes: RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase; EC=2.3.1.41; Includes: RecName: Full=3-oxoacyl-[acyl-carrier-protein] reductase; EC=1.1.1.100; Includes: RecName: Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase; EC=4.2.1.59; Includes: RecName: Full=Enoyl-[acyl-carrier-protein] reductase; EC=1.3.1.39; Includes: RecName: Full=Oleoyl-[acyl-carrier-protein] hydrolase; EC=3.1.2.14;+++[A0A087WTM9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 6 {ECO:0000313|Ensembl:ENSP00000477997};+++[A0A0U1RQF0_HUMAN|Unreviewed]SubName: Full=Fatty acid synthase {ECO:0000313|Ensembl:ENSP00000488964};+++[A0A0U1RRG3_HUMAN|Unreviewed]SubName: Full=Fatty acid synthase {ECO:0000313|Ensembl:ENSP00000489514}; Flags: Fragment;+++[A0A1B0GTR5_HUMAN|Unreviewed]SubName: Full=Fatty acid synthase {ECO:0000313|Ensembl:ENSP00000489808}; Flags: Fragment;+++[A0A1B0GVK4_HUMAN|Unreviewed]SubName: Full=Fatty acid synthase {ECO:0000313|Ensembl:ENSP00000490553}; Flags: Fragment;+++[A0A1B0GWG8_HUMAN|Unreviewed]SubName: Full=Fatty acid synthase {ECO:0000313|Ensembl:ENSP00000490921}; Flags: Fragment;+++[E6Y7C3_HUMAN|Unreviewed]SubName: Full=FAS variant {ECO:0000313|EMBL:ACP28876.1};+++[E6Y7C4_HUMAN|Unreviewed]SubName: Full=FAS variant {ECO:0000313|EMBL:ACP28877.1};+++[F0UWG7_HUMAN|Unreviewed]SubName: Full=FAS 827dupA variant {ECO:0000313|EMBL:ACC91884.1};+++[H7C5Z8_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 6 {ECO:0000313|Ensembl:ENSP00000345601};+++[J3KTF0_HUMAN|Unreviewed]SubName: Full=Fatty acid synthase {ECO:0000313|Ensembl:ENSP00000462949}; Flags: Fragment;+++[Q6PJJ3_HUMAN|Unreviewed]SubName: Full=FASN protein {ECO:0000313|EMBL:AAH14631.1}; Flags: Fragment;+++[Q9UET8_HUMAN|Unreviewed]SubName: Full=Apoptosis signaling receptor FAS {ECO:0000313|EMBL:AAC16237.1}; Flags: Fragment;+++[S5PSV7_HUMAN|Unreviewed]SubName: Full=FAS {ECO:0000313|EMBL:AGR88648.1}; Flags: Fragment;+++[S5PZ57_HUMAN|Unreviewed]SubName: Full=FAS {ECO:0000313|EMBL:AGR88646.1}; Flags: Fragment;"]
[219738,"'FAM241B'",83,73,68,74.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"family with sequence similarity 241 member B","[F241B_HUMAN|Reviewed]RecName: Full=Uncharacterized protein FAM241B;+++[A0A024QZL0_HUMAN|Unreviewed]SubName: Full=Chromosome 10 open reading frame 35, isoform CRA_a {ECO:0000313|EMBL:EAW54332.1};+++[Q5VVH9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein FAM241B {ECO:0000313|Ensembl:ENSP00000398621}; Flags: Fragment;"]
[220,"'ALDH1A3'",6502,6957,6604,6687.66666666667,"00980///Metabolism of xenobiotics by cytochrome P450+++01110///Biosynthesis of secondary metabolites+++00360///Phenylalanine metabolism+++01100///Metabolic pathways+++00410///beta-Alanine metabolism+++05204///Chemical carcinogenesis+++01120///Microbial metabolism in diverse environments+++00350///Tyrosine metabolism+++00982///Drug metabolism - cytochrome P450+++00010///Glycolysis / Gluconeogenesis+++00340///Histidine metabolism","H01027///Anophthalmia and microphthalmia (A/M)",null,"R02537///Aldehyde:NADP+ oxidoreductase   Phenylacetaldehyde + NADP+ + H2O <=> Phenylacetic acid + NADPH + H++++R08307///3-carbamoyl-2-phenylpropionaldehyde:NAD+ oxidoreductase   3-Carbamoyl-2-phenylpropionaldehyde + NAD+ + H2O <=> 3-Carbamoyl-2-phenylpropionic acid + NADH + H++++R00904///3-aminopropanal:NAD+ oxidoreductase   3-Aminopropanal + NAD+ + H2O <=> beta-Alanine + NADH + H++++R03300///3,4-Dihydroxyphenylacetaldehyde:NAD+ oxidoreductase   3,4-Dihydroxyphenylacetaldehyde + NAD+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADH + H++++R00711///Acetaldehyde:NADP+ oxidoreductase   Acetaldehyde + NADP+ + H2O <=> Acetate + NADPH + H++++R02536///Phenylacetaldehyde:NAD+ oxidoreductase   Phenylacetaldehyde + NAD+ + H2O <=> Phenylacetic acid + NADH + H++++R08283///carboxyphosphamide:NADP+ oxidoreductase   Aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H++++R04889///3-Methoxy-4-hydroxyphenylacetaldehyde:NADP+ oxidoreductase   3-Methoxy-4-hydroxyphenylacetaldehyde + NADP+ + H2O <=> Homovanillate + NADPH + H++++R04882///3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase   3,4-Dihydroxymandelaldehyde + NAD+ + H2O <=> 3,4-Dihydroxymandelate + NADH + H++++R04892///3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase   3-Methoxy-4-hydroxyphenylglycolaldehyde + NADP+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADPH + H++++R04996///3-Methylimidazole acetaldehyde:NAD+ oxidoreductase   Methylimidazole acetaldehyde + NAD+ + H2O <=> Methylimidazoleacetic acid + NADH + H++++R04883///3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase   3,4-Dihydroxymandelaldehyde + NADP+ + H2O <=> 3,4-Dihydroxymandelate + NADPH + H++++R02697///4-Hydroxyphenylacetaldehyde:NADP+ oxidoreductase   4-Hydroxyphenylacetaldehyde + NADP+ + H2O <=> 4-Hydroxyphenylacetate + NADPH + H++++R02695///4-Hydroxyphenylacetaldehyde:NAD+ oxidoreductase   4-Hydroxyphenylacetaldehyde + NAD+ + H2O <=> 4-Hydroxyphenylacetate + NADH + H++++R07104///Chloral:NAD(P)+ oxidoreductase   Chloral hydrate + NAD+ <=> Trichloroacetate + NADH + H++++R03302///3,4-Dihydroxyphenylacetaldehyde:NADP+ oxidoreductase   3,4-Dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H++++R08282///carboxyphosphamide:NAD+ oxidoreductase   Aldophosphamide + NAD+ + H2O <=> Carboxyphosphamide + NADH + H++++R04891///3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase   3-Methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADH + H++++R04888///3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase   3-Methoxy-4-hydroxyphenylacetaldehyde + NAD+ + H2O <=> Homovanillate + NADH + H+","GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0001758///retinal dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0070324///thyroid hormone binding+++GO:0042803///protein homodimerization activity+++GO:0004030///aldehyde dehydrogenase [NAD(P)+] activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0070403///NAD+ binding","GO:0042573///retinoic acid metabolic process+++GO:0060166///olfactory pit development+++GO:0002072///optic cup morphogenesis involved in camera-type eye development+++GO:0051289///protein homotetramerization+++GO:0048048///embryonic eye morphogenesis+++GO:0031076///embryonic camera-type eye development+++GO:0043584///nose development+++GO:0042472///inner ear morphogenesis+++GO:0060324///face development+++GO:0043065///positive regulation of apoptotic process+++GO:0021768///nucleus accumbens development+++GO:0055114///oxidation-reduction process+++GO:0042574///retinal metabolic process+++GO:0050885///neuromuscular process controlling balance+++GO:0002138///retinoic acid biosynthetic process+++GO:0070384///Harderian gland development+++GO:0007626///locomotory behavior+++GO:0042572///retinol metabolic process+++GO:0060013///righting reflex","aldehyde dehydrogenase 1 family member A3","[AL1A3_HUMAN|Reviewed]RecName: Full=Aldehyde dehydrogenase family 1 member A3; EC=1.2.1.5 {ECO:0000269|PubMed:27759097}; AltName: Full=Aldehyde dehydrogenase 6; AltName: Full=Retinaldehyde dehydrogenase 3; Short=RALDH-3; Short=RalDH3;+++[A0A024RC95_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase 1 family, member A3, isoform CRA_a {ECO:0000313|EMBL:EAX02282.1};+++[H0Y2X5_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase 1 family, member A3, isoform CRA_b {ECO:0000313|EMBL:EAX02283.1}; SubName: Full=Aldehyde dehydrogenase family 1 member A3 {ECO:0000313|Ensembl:ENSP00000343294};+++[H0YKF9_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase family 1 member A3 {ECO:0000313|Ensembl:ENSP00000452789}; Flags: Fragment;+++[H0YLT1_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase family 1 member A3 {ECO:0000313|Ensembl:ENSP00000453328};+++[H0YNQ3_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase family 1 member A3 {ECO:0000313|Ensembl:ENSP00000454107};+++[Q7Z3A2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G1675 {ECO:0000313|EMBL:CAD97973.1}; Flags: Fragment;"]
[220164,"'DOK6'",101,84,91,92,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04514///Cell adhesion molecules (CAMs)","H00408///Type I diabetes mellitus",null,null,"GO:0005829///cytosol","GO:0005515///protein binding","GO:0007411///axon guidance","docking protein 6","[DOK6_HUMAN|Reviewed]RecName: Full=Docking protein 6; AltName: Full=Downstream of tyrosine kinase 6;+++[J3KTH4_HUMAN|Unreviewed]SubName: Full=Docking protein 6 {ECO:0000313|Ensembl:ENSP00000462984}; Flags: Fragment;"]
[220963,"'SLC16A9'",170,186,163,173,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0015293///symporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity","GO:0015718///monocarboxylic acid transport+++GO:0055085///transmembrane transport+++GO:0046415///urate metabolic process","solute carrier family 16 member 9","[MOT9_HUMAN|Reviewed]RecName: Full=Monocarboxylate transporter 9; Short=MCT 9; AltName: Full=Solute carrier family 16 member 9;"]
[221092,"'HNRNPUL2'",2701,2701,2566,2656,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003723///RNA binding","GO:0008150///biological_process","heterogeneous nuclear ribonucleoprotein U like 2","[HNRL2_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 2; AltName: Full=Scaffold-attachment factor A2; Short=SAF-A2;+++[L8E7F7_HUMAN|Unreviewed]SubName: Full=Alternative protein HNRNPUL2 {ECO:0000313|EMBL:CCQ43064.1};"]
[221393,"'ADGRF4'",2,1,3,2,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway","adhesion G protein-coupled receptor F4","[AGRF4_HUMAN|Reviewed]RecName: Full=Adhesion G protein-coupled receptor F4; AltName: Full=G-protein coupled receptor 115; AltName: Full=G-protein coupled receptor PGR18; Flags: Precursor;+++[A0A0C4DFV3_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor F4 {ECO:0000313|Ensembl:ENSP00000360264};"]
[221496,"'LEMD2'",779,734,715,742.666666666667,{"$nulls":4},"GO:0031965///nuclear membrane+++GO:0016021///integral component of membrane+++GO:0000785///chromatin+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005639///integral component of nuclear inner membrane+++GO:0005634///nucleus+++GO:0005637///nuclear inner membrane","GO:0005515///protein binding","GO:0022008///neurogenesis+++GO:1902531///regulation of intracellular signal transduction+++GO:0043409///negative regulation of MAPK cascade+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0035914///skeletal muscle cell differentiation+++GO:0071168///protein localization to chromatin+++GO:0006998///nuclear envelope organization+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0060914///heart formation","LEM domain containing 2","[LEMD2_HUMAN|Reviewed]RecName: Full=LEM domain-containing protein 2; Short=hLEM2;+++[A0A024RCZ1_HUMAN|Unreviewed]SubName: Full=LEM domain containing 2, isoform CRA_a {ECO:0000313|EMBL:EAX03751.1};+++[A0A220T1R7_HUMAN|Unreviewed]SubName: Full=LEMD2 {ECO:0000313|EMBL:ASK40096.1};+++[D6R958_HUMAN|Unreviewed]SubName: Full=LEM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423619}; Flags: Fragment;+++[D6RBV0_HUMAN|Unreviewed]SubName: Full=LEM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000398733};+++[H0Y8H8_HUMAN|Unreviewed]SubName: Full=LEM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000421112}; Flags: Fragment;+++[H0Y9B7_HUMAN|Unreviewed]SubName: Full=LEM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423715}; Flags: Fragment;+++[H7C2Z0_HUMAN|Unreviewed]SubName: Full=LEM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000408524}; Flags: Fragment;"]
[221806,"'VWDE'",18,26,15,19.6666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0009986///cell surface","GO:0005509///calcium ion binding+++GO:0005102///signaling receptor binding","GO:0048856///anatomical structure development","von Willebrand factor D and EGF domains","[VWDE_HUMAN|Reviewed]RecName: Full=von Willebrand factor D and EGF domain-containing protein; Flags: Precursor;+++[A0A087WXZ2_HUMAN|Unreviewed]SubName: Full=von Willebrand factor D and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000481403};+++[A0A0C4DH13_HUMAN|Unreviewed]SubName: Full=von Willebrand factor D and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000317143};+++[A0A2R8YEP3_HUMAN|Unreviewed]SubName: Full=von Willebrand factor D and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000495749}; Flags: Fragment;+++[E5RG96_HUMAN|Unreviewed]SubName: Full=von Willebrand factor D and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000428810};+++[J3KQJ9_HUMAN|Unreviewed]SubName: Full=von Willebrand factor D and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000401687};"]
[2222,"'FDFT1'",2210,2413.93,2178,2267.31,"00100///Steroid biosynthesis+++00909///Sesquiterpenoid and triterpenoid biosynthesis+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites",null,null,"R06223///squalene synthase   2 trans,trans-Farnesyl diphosphate + NADPH + H+ <=> Squalene + 2 Diphosphate + NADP++++R02872///presqualene-diphosphate diphosphate-lyase (reducing, squalene-forming)   Presqualene diphosphate + NADPH + H+ <=> Diphosphate + Squalene + NADP++++R00702///farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase   2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate","GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0004310///farnesyl-diphosphate farnesyltransferase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups+++GO:0051996///squalene synthase activity+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0016740///transferase activity","GO:0045338///farnesyl diphosphate metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0019216///regulation of lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006696///ergosterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0008610///lipid biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0008152///metabolic process","farnesyl-diphosphate farnesyltransferase 1","[FDFT_HUMAN|Reviewed]RecName: Full=Squalene synthase; Short=SQS; Short=SS; EC=2.5.1.21; AltName: Full=FPP:FPP farnesyltransferase; AltName: Full=Farnesyl-diphosphate farnesyltransferase;+++[A0A1W2PQ47_HUMAN|Unreviewed]SubName: Full=Squalene synthase {ECO:0000313|Ensembl:ENSP00000491537};+++[B4DND3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55760, highly similar to Squalene synthetase {ECO:0000313|EMBL:BAG60195.1}; SubName: Full=cDNA, FLJ79081, highly similar to Squalene synthetase {ECO:0000313|EMBL:BAH14553.1};+++[B4DWP0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53107, highly similar to Squalene synthetase {ECO:0000313|EMBL:BAG63102.1};+++[B7Z9R8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78932, highly similar to Squalene synthetase {ECO:0000313|EMBL:BAH14404.1};+++[E9PJG4_HUMAN|Unreviewed]SubName: Full=Squalene synthase {ECO:0000313|Ensembl:ENSP00000431852}; Flags: Fragment;+++[E9PNJ2_HUMAN|Unreviewed]SubName: Full=Squalene synthase {ECO:0000313|Ensembl:ENSP00000434770};+++[E9PNM1_HUMAN|Unreviewed]SubName: Full=Squalene synthase {ECO:0000313|Ensembl:ENSP00000434714};+++[E9PQ90_HUMAN|Unreviewed]SubName: Full=Squalene synthase {ECO:0000313|Ensembl:ENSP00000432551};+++[E9PS69_HUMAN|Unreviewed]SubName: Full=Squalene synthase {ECO:0000313|Ensembl:ENSP00000435900};+++[E9PSH1_HUMAN|Unreviewed]SubName: Full=Squalene synthase {ECO:0000313|Ensembl:ENSP00000433985};+++[Q6IAX1_HUMAN|Unreviewed]SubName: Full=FDFT1 protein {ECO:0000313|EMBL:CAG33314.1}; SubName: Full=Farnesyl-diphosphate farnesyltransferase 1 {ECO:0000313|EMBL:AAP35350.1}; SubName: Full=Farnesyl-diphosphate farnesyltransferase 1, isoform CRA_a {ECO:0000313|EMBL:EAW65628.1};"]
[222553,"'SLC35F1'",27,25,35,29,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport","solute carrier family 35 member F1","[S35F1_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member F1;"]
[2239,"'GPC4'",440,398,334,390.666666666667,"04310///Wnt signaling pathway",{"$nulls":3},"GO:0045202///synapse+++GO:0043202///lysosomal lumen+++GO:0031225///anchored component of membrane+++GO:0016020///membrane+++GO:0046658///anchored component of plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0062023///collagen-containing extracellular matrix+++GO:0099026///anchored component of presynaptic membrane+++GO:0005796///Golgi lumen+++GO:0098978///glutamatergic synapse+++GO:0005886///plasma membrane+++GO:0005576///extracellular region","GO:1904929///coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway","GO:1905606///regulation of presynapse assembly+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0099560///synaptic membrane adhesion+++GO:0009966///regulation of signal transduction+++GO:0006027///glycosaminoglycan catabolic process+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0001523///retinoid metabolic process","glypican 4","[GPC4_HUMAN|Reviewed]RecName: Full=Glypican-4; AltName: Full=K-glypican; Contains: RecName: Full=Secreted glypican-4; Flags: Precursor;+++[Q86SV6_HUMAN|Unreviewed]SubName: Full=K-glypican {ECO:0000313|EMBL:AAF22364.1};"]
[2256,"'FGF11'",1886,1712,1647,1748.33333333333,null,"H00606///Early infantile epileptic encephalopathy+++H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0005576///extracellular region","GO:0008083///growth factor activity","GO:0007267///cell-cell signaling+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0007399///nervous system development","fibroblast growth factor 11","[FGF11_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor 11; Short=FGF-11; AltName: Full=Fibroblast growth factor homologous factor 3; Short=FHF-3;+++[B7Z1C3_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442};+++[I3L4N4_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442};+++[Q6LA99_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442}; Flags: Fragment;"]
[2275,"'FHL3'",637,502,587,575.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0030018///Z disc+++GO:0001725///stress fiber","GO:0046872///metal ion binding+++GO:0003779///actin binding","GO:0030036///actin cytoskeleton organization+++GO:0007517///muscle organ development","four and a half LIM domains 3","[FHL3_HUMAN|Reviewed]RecName: Full=Four and a half LIM domains protein 3; Short=FHL-3; AltName: Full=Skeletal muscle LIM-protein 2; Short=SLIM-2;+++[Q96C98_HUMAN|Unreviewed]SubName: Full=FHL3 protein {ECO:0000313|EMBL:AAH14501.1};"]
[22824,"'HSPA4L'",221,202,179,200.666666666667,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006457///protein folding+++GO:0006986///response to unfolded protein","heat shock protein family A (Hsp70) member 4 like","[HS74L_HUMAN|Reviewed]RecName: Full=Heat shock 70 kDa protein 4L; AltName: Full=Heat shock 70-related protein APG-1; AltName: Full=Osmotic stress protein 94;+++[A0A140VKE7_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 64n {ECO:0000313|EMBL:AEE61284.1};+++[B4DXT2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59635, highly similar to Heat shock 70 kDa protein 4L {ECO:0000313|EMBL:BAG63494.1};+++[B4DZR0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55529, highly similar to Heat shock 70 kDa protein 4L {ECO:0000313|EMBL:BAG64172.1};+++[D6RJ96_HUMAN|Unreviewed]SubName: Full=Heat shock 70 kDa protein 4L {ECO:0000313|Ensembl:ENSP00000427305}; Flags: Fragment;+++[E9PDE8_HUMAN|Unreviewed]SubName: Full=Heat shock 70 kDa protein 4L {ECO:0000313|Ensembl:ENSP00000425645};"]
[22838,"'RNF44'",1840,2257,2035,2044,{"$nulls":5},"GO:0046872///metal ion binding","GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","ring finger protein 44","[RNF44_HUMAN|Reviewed]RecName: Full=RING finger protein 44;+++[A0A024R7Q1_HUMAN|Unreviewed]SubName: Full=Ring finger protein 44, isoform CRA_b {ECO:0000313|EMBL:EAW85072.1};+++[D6RAW5_HUMAN|Unreviewed]SubName: Full=RING finger protein 44 {ECO:0000313|Ensembl:ENSP00000424699};+++[D6RHW8_HUMAN|Unreviewed]SubName: Full=RING finger protein 44 {ECO:0000313|Ensembl:ENSP00000427604};+++[H0Y9W0_HUMAN|Unreviewed]SubName: Full=RING finger protein 44 {ECO:0000313|Ensembl:ENSP00000425253}; Flags: Fragment;"]
[22866,"'CNKSR2'",322,293,280,298.333333333333,"04013///MAPK signaling pathway - fly","H00658///Syndromic X-linked mental retardation",null,null,"GO:0014069///postsynaptic density+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0045211///postsynaptic membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0099147///extrinsic component of postsynaptic density membrane+++GO:0005886///plasma membrane+++GO:0043005///neuron projection","GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0042802///identical protein binding+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0099173///postsynapse organization+++GO:0019722///calcium-mediated signaling+++GO:0007265///Ras protein signal transduction+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0016310///phosphorylation+++GO:0009966///regulation of signal transduction+++GO:0035556///intracellular signal transduction","connector enhancer of kinase suppressor of Ras 2","[CNKR2_HUMAN|Reviewed]RecName: Full=Connector enhancer of kinase suppressor of ras 2; Short=Connector enhancer of KSR 2; AltName: Full=CNK homolog protein 2; Short=CNK2;+++[A0A2R8Y5R2_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000494983};+++[A0A2R8Y5S6_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000495012};+++[A0A2R8Y604_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000494962}; Flags: Fragment;+++[A0A2R8Y622_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000494906};+++[A0A2R8Y700_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000495695};+++[A0A2R8Y7A1_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000495954};+++[A0A2R8Y7K8_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000496186};+++[A0A2R8YDB6_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000494416};+++[A0A2R8YE27_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000495189};+++[A0A2R8YE65_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000495325}; Flags: Fragment;+++[A0A2R8YE71_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000494115}; Flags: Fragment;+++[A0A2R8YED7_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000495501};+++[A0A2R8YFM1_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000496573};+++[A0A2R8YGJ7_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000496088};+++[A0A2U3TZH5_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|Ensembl:ENSP00000279451};+++[B3KPN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31987 fis, clone NT2RP7008855, highly similar to Connector enhancer of kinase suppressor of ras 2 {ECO:0000313|EMBL:BAG51744.1};+++[L8E9Q3_HUMAN|Unreviewed]SubName: Full=Alternative protein CNKSR2 {ECO:0000313|EMBL:CCQ43471.1};"]
[22875,"'ENPP4'",289,279,348,305.333333333333,"00230///Purine metabolism",null,null,"R00187///P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase   P1,P3-Bis(5'-adenosyl) triphosphate + H2O <=> ADP + AMP","GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0101003///ficolin-1-rich granule membrane","GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0047710///bis(5'-adenosyl)-triphosphatase activity","GO:0043312///neutrophil degranulation+++GO:0046130///purine ribonucleoside catabolic process+++GO:0007596///blood coagulation+++GO:0007599///hemostasis+++GO:0030194///positive regulation of blood coagulation","ectonucleotide pyrophosphatase/phosphodiesterase 4","[ENPP4_HUMAN|Reviewed]RecName: Full=Bis(5'-adenosyl)-triphosphatase ENPP4; EC=3.6.1.29; AltName: Full=AP3A hydrolase; Short=AP3Aase; AltName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 4; Short=E-NPP 4; Short=NPP-4; Flags: Precursor;+++[L8ECF4_HUMAN|Unreviewed]SubName: Full=Alternative protein ENPP4 {ECO:0000313|EMBL:CCQ43472.1};"]
[2289,"'FKBP5'",450,456,364,423.333333333333,"04915///Estrogen signaling pathway","H01646///Major depressive disorder (MDD)",null,null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding","GO:0006457///protein folding+++GO:0009617///response to bacterium+++GO:0061077///chaperone-mediated protein folding+++GO:0000413///protein peptidyl-prolyl isomerization","FK506 binding protein 5","[FKBP5_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP5; Short=PPIase FKBP5; EC=5.2.1.8; AltName: Full=51 kDa FK506-binding protein; Short=51 kDa FKBP; Short=FKBP-51; AltName: Full=54 kDa progesterone receptor-associated immunophilin; AltName: Full=Androgen-regulated protein 6; AltName: Full=FF1 antigen; AltName: Full=FK506-binding protein 5; Short=FKBP-5; AltName: Full=FKBP54; Short=p54; AltName: Full=HSP90-binding immunophilin; AltName: Full=Rotamase;+++[L0R859_HUMAN|Unreviewed]SubName: Full=Alternative protein FKBP5 {ECO:0000313|EMBL:CCO13731.1};+++[L8EC85_HUMAN|Unreviewed]SubName: Full=Alternative protein FKBP5 {ECO:0000313|EMBL:CCQ43127.1};+++[Q2TA84_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};"]
[22901,"'ARSG'",424,512,530,488.666666666667,"04142///Lysosome",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005764///lysosome+++GO:0005788///endoplasmic reticulum lumen","GO:0003824///catalytic activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0004065///arylsulfatase activity+++GO:0046872///metal ion binding","GO:0006790///sulfur compound metabolic process","arylsulfatase G","[ARSG_HUMAN|Reviewed]RecName: Full=Arylsulfatase G; Short=ASG; EC=3.1.6.-; Flags: Precursor;+++[A0A024R8K1_HUMAN|Unreviewed]SubName: Full=Arylsulfatase G, isoform CRA_a {ECO:0000313|EMBL:EAW89056.1};+++[J3KS49_HUMAN|Unreviewed]SubName: Full=Arylsulfatase G {ECO:0000313|Ensembl:ENSP00000462306}; Flags: Fragment;+++[J9JIG6_HUMAN|Unreviewed]SubName: Full=Arylsulfatase G {ECO:0000313|Ensembl:ENSP00000413953};"]
[22931,"'RAB18'",892,680,752,774.666666666667,null,"H00792///Warburg micro syndrome",null,null,"GO:0045202///synapse+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005789///endoplasmic reticulum membrane+++GO:0030667///secretory granule membrane+++GO:0071782///endoplasmic reticulum tubular network","GO:0005515///protein binding+++GO:0019003///GDP binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity","GO:0051170///import into nucleus+++GO:0006886///intracellular protein transport+++GO:0032482///Rab protein signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0015031///protein transport+++GO:0001654///eye development+++GO:0043312///neutrophil degranulation+++GO:0034389///lipid droplet organization","RAB18, member RAS oncogene family","[RAB18_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-18; Flags: Precursor;+++[A0A087X163_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-18 {ECO:0000313|Ensembl:ENSP00000483927};+++[B7Z4P9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51678, highly similar to Ras-related protein Rab-18 {ECO:0000313|EMBL:BAH12635.1};+++[B7Z5V3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53088, highly similar to Ras-related protein Rab-18 {ECO:0000313|EMBL:BAH13039.1};+++[H0Y6T8_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-18 {ECO:0000313|Ensembl:ENSP00000407872}; Flags: Fragment;+++[Q5W0J0_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-18 {ECO:0000313|Ensembl:ENSP00000364960};"]
[22948,"'CCT5'",2166,2184,2073,2141,null,"H00265///Hereditary sensory and autonomic neuropathy (HSAN)",null,null,"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005832///chaperonin-containing T-complex+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0005874///microtubule+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0031681///G-protein beta-subunit binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0051082///unfolded protein binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0048487///beta-tubulin binding","GO:0006457///protein folding+++GO:0009615///response to virus+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0007339///binding of sperm to zona pellucida+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body","chaperonin containing TCP1 subunit 5","[TCPE_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit epsilon; Short=TCP-1-epsilon; AltName: Full=CCT-epsilon;+++[B4DDU6_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit epsilon {ECO:0000256|RuleBase:RU365043}; Short=TCP-1-epsilon {ECO:0000256|RuleBase:RU365043}; AltName: Full=CCT-epsilon {ECO:0000256|RuleBase:RU365043};+++[B4DX08_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit epsilon {ECO:0000256|RuleBase:RU365043}; Short=TCP-1-epsilon {ECO:0000256|RuleBase:RU365043}; AltName: Full=CCT-epsilon {ECO:0000256|RuleBase:RU365043};+++[B4DYC8_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit epsilon {ECO:0000256|RuleBase:RU365043}; Short=TCP-1-epsilon {ECO:0000256|RuleBase:RU365043}; AltName: Full=CCT-epsilon {ECO:0000256|RuleBase:RU365043};+++[B7ZAR1_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit epsilon {ECO:0000256|RuleBase:RU365043}; Short=TCP-1-epsilon {ECO:0000256|RuleBase:RU365043}; AltName: Full=CCT-epsilon {ECO:0000256|RuleBase:RU365043};+++[D6RIZ7_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit epsilon {ECO:0000313|Ensembl:ENSP00000425751};+++[E7ENZ3_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit epsilon {ECO:0000256|RuleBase:RU365043}; Short=TCP-1-epsilon {ECO:0000256|RuleBase:RU365043}; AltName: Full=CCT-epsilon {ECO:0000256|RuleBase:RU365043};+++[E9PCA1_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit epsilon {ECO:0000256|RuleBase:RU365043}; Short=TCP-1-epsilon {ECO:0000256|RuleBase:RU365043}; AltName: Full=CCT-epsilon {ECO:0000256|RuleBase:RU365043};+++[H0Y914_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit epsilon {ECO:0000313|Ensembl:ENSP00000422744}; Flags: Fragment;+++[H0Y958_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit epsilon {ECO:0000313|Ensembl:ENSP00000423087}; Flags: Fragment;+++[V9HW37_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit epsilon {ECO:0000256|RuleBase:RU365043}; Short=TCP-1-epsilon {ECO:0000256|RuleBase:RU365043}; AltName: Full=CCT-epsilon {ECO:0000256|RuleBase:RU365043};"]
[22989,"'MYH15'",4,6,5,5,"04530///Tight junction","H00872///Trismus-pseudocamptodactyly syndrome+++H01630///Patent ductus arteriosus+++H00801///Familial thoracic aortic aneurysm and dissection (TAAD)+++H00811///Distal arthrogryposis (DA)+++H01740///Macrothrombocytopenia+++H01229///Inclusion body myopathy 3 (IBM3)+++H00578///Epstein syndrome+++H00604///Deafness, autosomal dominant+++H00233///MYH9-related disease+++H02053///Fechtner syndrome+++H02051///May-Hegglin anomaly+++H02052///Sebastian syndrome",null,null,"GO:0030016///myofibril+++GO:0032982///myosin filament+++GO:0005737///cytoplasm+++GO:0016459///myosin complex","GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0005516///calmodulin binding+++GO:0051015///actin filament binding+++GO:0003774///motor activity","GO:0002074///extraocular skeletal muscle development","myosin heavy chain 15","[MYH15_HUMAN|Reviewed]RecName: Full=Myosin-15; AltName: Full=Myosin heavy chain 15;+++[H9XFA0_HUMAN|Unreviewed]SubName: Full=Myosin heavy chain 15 protein {ECO:0000313|EMBL:AFG72966.1}; Flags: Fragment;+++[L8E9Q8_HUMAN|Unreviewed]SubName: Full=Alternative protein MYH15 {ECO:0000313|EMBL:CCQ43476.1};"]
[23005,"'MAPKBP1'",907,1154,1095,1052,null,"H00537///Nephronophthisis",null,null,"GO:0097431///mitotic spindle pole+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0000922///spindle pole","GO:0016301///kinase activity+++GO:0005515///protein binding","GO:2000483///negative regulation of interleukin-8 secretion+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:1900425///negative regulation of defense response to bacterium+++GO:0016310///phosphorylation","mitogen-activated protein kinase binding protein 1","[MABP1_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase-binding protein 1; AltName: Full=JNK-binding protein 1; Short=JNKBP-1;+++[A0A024R9L5_HUMAN|Unreviewed]SubName: Full=Mitogen activated protein kinase binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW92518.1};+++[D6R9F7_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000422132}; Flags: Fragment;+++[D6RAI2_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000421891};+++[D6RHX7_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000427582};+++[L8E7J2_HUMAN|Unreviewed]SubName: Full=Alternative protein MAPKBP1 {ECO:0000313|EMBL:CCQ43099.1};"]
[2302,"'FOXJ1'",27,28,20,25,null,"H01360///Allergic rhinitis",null,null,"GO:0005634///nucleus","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030036///actin cytoskeleton organization+++GO:0007507///heart development+++GO:0044458///motile cilium assembly+++GO:0045409///negative regulation of interleukin-6 biosynthetic process+++GO:0035089///establishment of apical/basal cell polarity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007420///brain development+++GO:0030030///cell projection organization+++GO:0006959///humoral immune response+++GO:0033085///negative regulation of T cell differentiation in thymus+++GO:0007368///determination of left/right symmetry+++GO:0050900///leukocyte migration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060972///left/right pattern formation+++GO:0002635///negative regulation of germinal center formation+++GO:0002508///central tolerance induction+++GO:0090630///activation of GTPase activity+++GO:0002924///negative regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0030856///regulation of epithelial cell differentiation+++GO:0035502///metanephric part of ureteric bud development+++GO:0060428///lung epithelium development+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0042130///negative regulation of T cell proliferation+++GO:0072016///glomerular parietal epithelial cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:1901248///positive regulation of lung ciliated cell differentiation+++GO:0060429///epithelium development+++GO:0002897///positive regulation of central B cell tolerance induction+++GO:0050869///negative regulation of B cell activation+++GO:0060271///cilium assembly+++GO:0007389///pattern specification process","forkhead box J1","[FOXJ1_HUMAN|Reviewed]RecName: Full=Forkhead box protein J1 {ECO:0000305}; AltName: Full=Forkhead-related protein FKHL13 {ECO:0000303|PubMed:9073514}; AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 4 {ECO:0000303|PubMed:9530170}; Short=HFH-4 {ECO:0000303|PubMed:9530170};+++[A0A024R8P1_HUMAN|Unreviewed]SubName: Full=Forkhead box J1, isoform CRA_a {ECO:0000313|EMBL:EAW89376.1};"]
[2304,"'FOXE1'",8,5,9,7.33333333333333,null,"H01202///Cataract+++H01159///Anterior segment dysgenesis (ASGD)+++H01040///Bamforth-Lazarus syndrome+++H00801///Familial thoracic aortic aneurysm and dissection (TAAD)+++H00676///Congenital primary aphakia",null,null,"GO:0005681///spliceosomal complex+++GO:0008023///transcription elongation factor complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0004386///helicase activity+++GO:0008094///DNA-dependent ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity","GO:0060465///pharynx development+++GO:0006353///DNA-templated transcription, termination+++GO:0006590///thyroid hormone generation+++GO:0031069///hair follicle morphogenesis+++GO:0006397///mRNA processing+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060021///roof of mouth development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030878///thyroid gland development+++GO:0060022///hard palate development+++GO:0016477///cell migration+++GO:0006369///termination of RNA polymerase II transcription+++GO:0048538///thymus development+++GO:0048562///embryonic organ morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:1904888///cranial skeletal system development+++GO:0030154///cell differentiation+++GO:0009653///anatomical structure morphogenesis+++GO:0060023///soft palate development+++GO:0006357///regulation of transcription by RNA polymerase II","forkhead box E1","[FOXE1_HUMAN|Reviewed]RecName: Full=Forkhead box protein E1; AltName: Full=Forkhead box protein E2; AltName: Full=Forkhead-related protein FKHL15; AltName: Full=HFKH4; AltName: Full=HNF-3/fork head-like protein 5; Short=HFKL5; AltName: Full=Thyroid transcription factor 2; Short=TTF-2;"]
[23054,"'NCOA6'",1734,2057,1825,1872,{"$nulls":4},"GO:0005667///transcription factor complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0035097///histone methyltransferase complex","GO:0030331///estrogen receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0046965///retinoid X receptor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding","GO:0006310///DNA recombination+++GO:0007507///heart development+++GO:0007420///brain development+++GO:0030099///myeloid cell differentiation+++GO:0009725///response to hormone+++GO:0006260///DNA replication+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006352///DNA-templated transcription, initiation+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0019216///regulation of lipid metabolic process","nuclear receptor coactivator 6","[NCOA6_HUMAN|Reviewed]RecName: Full=Nuclear receptor coactivator 6; AltName: Full=Activating signal cointegrator 2; Short=ASC-2; AltName: Full=Amplified in breast cancer protein 3; AltName: Full=Cancer-amplified transcriptional coactivator ASC-2; AltName: Full=Nuclear receptor coactivator RAP250; Short=NRC RAP250; AltName: Full=Nuclear receptor-activating protein, 250 kDa; AltName: Full=Peroxisome proliferator-activated receptor-interacting protein; Short=PPAR-interacting protein; Short=PRIP; AltName: Full=Thyroid hormone receptor-binding protein;+++[A0A0D9SFT8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 6 {ECO:0000313|Ensembl:ENSP00000486894}; Flags: Fragment;+++[F6M2K2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 6 {ECO:0000313|Ensembl:ENSP00000481177}; SubName: Full=Nuclear receptor coactivator-6 beta {ECO:0000313|EMBL:AEG79564.1};+++[F6M2K3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator-6 gamma {ECO:0000313|EMBL:AEG79565.1};+++[F6M2K4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 6 {ECO:0000313|Ensembl:ENSP00000481935}; SubName: Full=Nuclear receptor coactivator-6 delta {ECO:0000313|EMBL:AEG79566.1};+++[Q1RMZ3_HUMAN|Unreviewed]SubName: Full=NCOA6 protein {ECO:0000313|EMBL:AAI14614.1}; Flags: Fragment;"]
[23076,"'RRP1B'",818,891,909,872.666666666667,{"$nulls":4},"GO:0000792///heterochromatin+++GO:0001652///granular component+++GO:0030687///preribosome, large subunit precursor+++GO:0005829///cytosol+++GO:0000791///euchromatin+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0030688///preribosome, small subunit precursor+++GO:0005694///chromosome","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0043065///positive regulation of apoptotic process+++GO:0043484///regulation of RNA splicing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0010923///negative regulation of phosphatase activity+++GO:0098586///cellular response to virus+++GO:0006915///apoptotic process+++GO:0006364///rRNA processing+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0034260///negative regulation of GTPase activity","ribosomal RNA processing 1B","[RRP1B_HUMAN|Reviewed]RecName: Full=Ribosomal RNA processing protein 1 homolog B; AltName: Full=RRP1-like protein B;+++[D6RE82_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA-processing protein 1 homolog A {ECO:0000313|Ensembl:ENSP00000426898};+++[Q6PJJ2_HUMAN|Unreviewed]SubName: Full=RRP1 protein {ECO:0000313|EMBL:AAH14787.3}; Flags: Fragment;+++[Q6PJM8_HUMAN|Unreviewed]SubName: Full=RRP1B protein {ECO:0000313|EMBL:AAH14005.1}; Flags: Fragment;"]
[23094,"'SIPA1L3'",1563,2041,1786,1796.66666666667,"04015///Rap1 signaling pathway","H01202///Cataract",null,null,"GO:0005615///extracellular space+++GO:0001725///stress fiber+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0061689///tricellular tight junction+++GO:0005886///plasma membrane+++GO:0045177///apical part of cell","GO:0005096///GTPase activator activity","GO:0007010///cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0001654///eye development+++GO:0003382///epithelial cell morphogenesis+++GO:0090162///establishment of epithelial cell polarity+++GO:0051056///regulation of small GTPase mediated signal transduction","signal induced proliferation associated 1 like 3","[SI1L3_HUMAN|Reviewed]RecName: Full=Signal-induced proliferation-associated 1-like protein 3; Short=SIPA1-like protein 3; AltName: Full=SPA-1-like protein 3;+++[B2RWP0_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated 1 like 3 {ECO:0000313|EMBL:AAI50621.1};+++[M0QX89_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated 1-like protein 3 {ECO:0000313|Ensembl:ENSP00000468981}; Flags: Fragment;+++[M0R2Q7_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated 1-like protein 3 {ECO:0000313|Ensembl:ENSP00000472734}; Flags: Fragment;+++[Q8IUV1_HUMAN|Unreviewed]SubName: Full=SIPA1L3 protein {ECO:0000313|EMBL:AAH36863.1}; Flags: Fragment;"]
[23114,"'NFASC'",2323,1713,1631,1889,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0030424///axon+++GO:0043194///axon initial segment+++GO:0033268///node of Ranvier+++GO:0016020///membrane+++GO:0097454///Schwann cell microvillus+++GO:0033270///paranode region of axon+++GO:0043209///myelin sheath+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0005925///focal adhesion+++GO:0016021///integral component of membrane+++GO:0033010///paranodal junction+++GO:0101003///ficolin-1-rich granule membrane","GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion","GO:0050808///synapse organization+++GO:0071205///protein localization to juxtaparanode region of axon+++GO:0043312///neutrophil degranulation+++GO:0002175///protein localization to paranode region of axon+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0030913///paranodal junction assembly+++GO:0034113///heterotypic cell-cell adhesion+++GO:0019226///transmission of nerve impulse+++GO:0007422///peripheral nervous system development+++GO:0042552///myelination+++GO:0007411///axon guidance+++GO:0072659///protein localization to plasma membrane+++GO:0007155///cell adhesion","neurofascin","[NFASC_HUMAN|Reviewed]RecName: Full=Neurofascin; Flags: Precursor;+++[A0A0C4DG92_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000416891}; Flags: Fragment;+++[B4DRH7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61350, highly similar to Neurofascin {ECO:0000313|EMBL:BAG61289.1};+++[D6RBU5_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000422524};+++[D6RHX4_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000427586}; Flags: Fragment;+++[H7BY57_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000356141}; Flags: Fragment;+++[H7C073_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000393290}; Flags: Fragment;+++[H7C0L6_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000395664}; Flags: Fragment;+++[X6RKN2_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000415031}; Flags: Fragment;"]
[23135,"'KDM6B'",1823,2131,1845,1933,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0044666///MLL3/4 complex+++GO:0005634///nucleus","GO:0051213///dioxygenase activity+++GO:0032452///histone demethylase activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0008013///beta-catenin binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding","GO:0021766///hippocampus development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0060992///response to fungicide+++GO:0014823///response to activity+++GO:0071557///histone H3-K27 demethylation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0016577///histone demethylation+++GO:0006338///chromatin remodeling+++GO:0045165///cell fate commitment+++GO:0055007///cardiac muscle cell differentiation+++GO:0006325///chromatin organization+++GO:0045446///endothelial cell differentiation+++GO:0010468///regulation of gene expression+++GO:0055114///oxidation-reduction process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0048333///mesodermal cell differentiation+++GO:0006954///inflammatory response","lysine demethylase 6B","[KDM6B_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 6B; EC=1.14.11.- {ECO:0000269|PubMed:17713478, ECO:0000269|PubMed:17825402, ECO:0000269|PubMed:17851529, ECO:0000269|PubMed:18003914}; AltName: Full=JmjC domain-containing protein 3; AltName: Full=Jumonji domain-containing protein 3; AltName: Full=Lysine demethylase 6B;+++[I3L0Z0_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 6B {ECO:0000313|Ensembl:ENSP00000458445}; Flags: Fragment;"]
[23151,"'GRAMD4'",964,1249,1120,1111,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane","GO:0003674///molecular_function","GO:0006915///apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process","GRAM domain containing 4","[GRAM4_HUMAN|Reviewed]RecName: Full=GRAM domain-containing protein 4; AltName: Full=Death-inducing protein;+++[H0Y5A3_HUMAN|Unreviewed]SubName: Full=GRAM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000397501}; Flags: Fragment;+++[X6RHZ2_HUMAN|Unreviewed]SubName: Full=GRAM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000408042}; Flags: Fragment;+++[X6RIP6_HUMAN|Unreviewed]SubName: Full=GRAM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000409784}; Flags: Fragment;"]
[23168,"'RTF1'",1592,1530,1471,1531,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0016593///Cdc73/Paf1 complex","GO:1990269///RNA polymerase II C-terminal domain phosphoserine binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding","GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001711///endodermal cell fate commitment+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0016570///histone modification+++GO:0016055///Wnt signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0080182///histone H3-K4 trimethylation+++GO:0019827///stem cell population maintenance+++GO:0001832///blastocyst growth+++GO:0016567///protein ubiquitination","RTF1 homolog, Paf1/RNA polymerase II complex component","[RTF1_HUMAN|Reviewed]RecName: Full=RNA polymerase-associated protein RTF1 homolog;+++[H0YKX1_HUMAN|Unreviewed]SubName: Full=RNA polymerase-associated protein RTF1 homolog {ECO:0000313|Ensembl:ENSP00000452973}; Flags: Fragment;"]
[23184,"'MESD'",1018,1060,1044,1040.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005575///cellular_component","GO:0042802///identical protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0003674///molecular_function","GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:0016055///Wnt signaling pathway+++GO:0006457///protein folding+++GO:0007498///mesoderm development+++GO:0034394///protein localization to cell surface+++GO:0006909///phagocytosis","mesoderm development LRP chaperone","[MESD_HUMAN|Reviewed]RecName: Full=LRP chaperone MESD {ECO:0000305}; AltName: Full=LDLR chaperone MESD; AltName: Full=Mesoderm development LRP chaperone MESD {ECO:0000312|HGNC:HGNC:13520}; AltName: Full=Mesoderm development candidate 2; AltName: Full=Mesoderm development protein; AltName: Full=Renal carcinoma antigen NY-REN-61; Flags: Precursor;+++[H0YLI4_HUMAN|Unreviewed]SubName: Full=LRP chaperone MESD {ECO:0000313|Ensembl:ENSP00000453220};"]
[23186,"'RCOR1'",661,600,587,616,"05016///Huntington's disease",{"$nulls":3},"GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:1990391///DNA repair complex+++GO:0005667///transcription factor complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0006325///chromatin organization+++GO:0016032///viral process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0070933///histone H4 deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007596///blood coagulation","REST corepressor 1","[RCOR1_HUMAN|Reviewed]RecName: Full=REST corepressor 1; AltName: Full=Protein CoREST;+++[H0YNY4_HUMAN|Unreviewed]SubName: Full=REST corepressor 1 {ECO:0000313|Ensembl:ENSP00000454204}; Flags: Fragment;+++[L0R8D2_HUMAN|Unreviewed]SubName: Full=Alternative protein RCOR1 {ECO:0000313|EMBL:CCO13801.1};"]
[23217,"'ZFR2'",37,33,42,37.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003725///double-stranded RNA binding+++GO:0008270///zinc ion binding+++GO:0003727///single-stranded RNA binding+++GO:0003676///nucleic acid binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","zinc finger RNA binding protein 2","[ZFR2_HUMAN|Reviewed]RecName: Full=Zinc finger RNA-binding protein 2;+++[K7EKD7_HUMAN|Unreviewed]SubName: Full=Zinc finger RNA-binding protein 2 {ECO:0000313|Ensembl:ENSP00000465574}; Flags: Fragment;+++[K7EPY6_HUMAN|Unreviewed]SubName: Full=Zinc finger RNA-binding protein 2 {ECO:0000313|Ensembl:ENSP00000467592};+++[K7EQC0_HUMAN|Unreviewed]SubName: Full=Zinc finger RNA-binding protein 2 {ECO:0000313|Ensembl:ENSP00000467762};"]
[23220,"'DTX4'",1272,1307,1160,1246.33333333333,"04330///Notch signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding","GO:0032479///regulation of type I interferon production+++GO:0016567///protein ubiquitination+++GO:0007219///Notch signaling pathway","deltex E3 ubiquitin ligase 4","[DTX4_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase DTX4; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q61010}; AltName: Full=Protein deltex-4; Short=Deltex4; AltName: Full=RING finger protein 155; AltName: Full=RING-type E3 ubiquitin transferase DTX4 {ECO:0000305};"]
[23235,"'SIK2'",1176,1213,1118,1169,"04922///Glucagon signaling pathway",{"$nulls":3},"GO:0031588///nucleotide-activated protein kinase complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0000287///magnesium ion binding","GO:0016310///phosphorylation+++GO:0032007///negative regulation of TOR signaling+++GO:0046777///protein autophosphorylation+++GO:0042149///cellular response to glucose starvation+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0046626///regulation of insulin receptor signaling pathway","salt inducible kinase 2","[SIK2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase SIK2; EC=2.7.11.1; AltName: Full=Qin-induced kinase; AltName: Full=Salt-inducible kinase 2; Short=SIK-2; AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 2;+++[A0A024R3G7_HUMAN|Unreviewed]SubName: Full=SNF1-like kinase 2, isoform CRA_c {ECO:0000313|EMBL:EAW67149.1};"]
[23252,"'OTUD3'",162,164,163.47,163.156666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity","GO:0051898///negative regulation of protein kinase B signaling+++GO:0044313///protein K6-linked deubiquitination+++GO:0050821///protein stabilization+++GO:0006508///proteolysis+++GO:1990167///protein K27-linked deubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0016579///protein deubiquitination+++GO:0071108///protein K48-linked deubiquitination","OTU deubiquitinase 3","[OTUD3_HUMAN|Reviewed]RecName: Full=OTU domain-containing protein 3; EC=3.4.19.12;+++[Q0VDK5_HUMAN|Unreviewed]SubName: Full=OTUD3 protein {ECO:0000313|EMBL:AAI19637.1};"]
[23274,"'CLEC16A'",1071,1122,973,1055.33333333333,"04612///Antigen processing and presentation+++05145///Toxoplasmosis+++04140///Autophagy - animal+++05152///Tuberculosis+++04137///Mitophagy - animal+++05340///Primary immunodeficiency+++05164///Influenza A","H00408///Type I diabetes mellitus",null,null,"GO:0036020///endolysosome membrane+++GO:0016020///membrane+++GO:0005770///late endosome+++GO:0031982///vesicle+++GO:0010008///endosome membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005768///endosome+++GO:0005764///lysosome","GO:0003674///molecular_function+++GO:0017137///Rab GTPase binding","GO:0008333///endosome to lysosome transport+++GO:1901097///negative regulation of autophagosome maturation+++GO:0016197///endosomal transport+++GO:0006914///autophagy+++GO:1904766///negative regulation of macroautophagy by TORC1 signaling+++GO:0009267///cellular response to starvation+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1901525///negative regulation of mitophagy+++GO:1904263///positive regulation of TORC1 signaling+++GO:1901098///positive regulation of autophagosome maturation","C-type lectin domain containing 16A","[CL16A_HUMAN|Reviewed]RecName: Full=Protein CLEC16A {ECO:0000305}; AltName: Full=C-type lectin domain family 16 member A {ECO:0000312|HGNC:HGNC:29013};+++[A0A2R8YDG4_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000493756}; Flags: Fragment;+++[H7BXG1_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000261657}; Flags: Fragment;+++[H7BZI2_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000389743}; Flags: Fragment;+++[H7BZJ9_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000389963}; Flags: Fragment;"]
[23288,"'IQCE'",1103,1182,971,1085.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016020///membrane+++GO:0060170///ciliary membrane+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0005929///cilium","GO:0005515///protein binding","GO:0035108///limb morphogenesis","IQ motif containing E","[IQCE_HUMAN|Reviewed]RecName: Full=IQ domain-containing protein E;+++[A0A024R853_HUMAN|Unreviewed]SubName: Full=IQ motif containing E, isoform CRA_b {ECO:0000313|EMBL:EAW87264.1};+++[A0A087WX19_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein E {ECO:0000313|Ensembl:ENSP00000480668};+++[A0A087WX45_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein E {ECO:0000313|Ensembl:ENSP00000480715}; SubName: Full=IQ motif containing E, isoform CRA_c {ECO:0000313|EMBL:EAW87263.1};+++[B3KRY4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ35085 fis, clone PLACE6005487, highly similar to Homo sapiens IQ motif containing E (IQCE), mRNA {ECO:0000313|EMBL:BAG52546.1};+++[B4DDX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53968, highly similar to Homo sapiens IQ motif containing E (IQCE), mRNA {ECO:0000313|EMBL:BAG56885.1};+++[B4DXN1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53236, highly similar to Homo sapiens IQ motif containing E (IQCE), mRNA {ECO:0000313|EMBL:BAG63443.1};+++[C9J5R6_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein E {ECO:0000313|Ensembl:ENSP00000405982}; Flags: Fragment;+++[C9JE72_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein E {ECO:0000313|Ensembl:ENSP00000404643}; Flags: Fragment;+++[C9JP75_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein E {ECO:0000313|Ensembl:ENSP00000402108}; Flags: Fragment;+++[H7C427_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein E {ECO:0000313|Ensembl:ENSP00000415261}; Flags: Fragment;+++[X5D7Y5_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein E {ECO:0000313|Ensembl:ENSP00000314011}; SubName: Full=IQ motif containing E isoform B {ECO:0000313|EMBL:AHW56720.1};+++[X5D951_HUMAN|Unreviewed]SubName: Full=IQ motif containing E isoform C {ECO:0000313|EMBL:AHW56513.1}; Flags: Fragment;+++[X5DR21_HUMAN|Unreviewed]SubName: Full=IQ motif containing E isoform A {ECO:0000313|EMBL:AHW56512.1}; Flags: Fragment;"]
[23314,"'SATB2'",42,61,36,46.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000118///histone deacetylase complex+++GO:0005667///transcription factor complex+++GO:0016363///nuclear matrix","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding","GO:0001764///neuron migration+++GO:0071310///cellular response to organic substance+++GO:0060021///roof of mouth development+++GO:0006325///chromatin organization+++GO:0002076///osteoblast development+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051216///cartilage development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0009880///embryonic pattern specification+++GO:0006338///chromatin remodeling+++GO:0010468///regulation of gene expression+++GO:0007275///multicellular organism development+++GO:0048704///embryonic skeletal system morphogenesis","SATB homeobox 2","[SATB2_HUMAN|Reviewed]RecName: Full=DNA-binding protein SATB2; AltName: Full=Special AT-rich sequence-binding protein 2;+++[A0A024R3U6_HUMAN|Unreviewed]RecName: Full=DNA-binding protein SATB {ECO:0000256|RuleBase:RU361129}; AltName: Full=Special AT-rich sequence-binding protein {ECO:0000256|RuleBase:RU361129};+++[B3KPQ9_HUMAN|Unreviewed]RecName: Full=DNA-binding protein SATB {ECO:0000256|RuleBase:RU361129}; AltName: Full=Special AT-rich sequence-binding protein {ECO:0000256|RuleBase:RU361129};+++[C9JR56_HUMAN|Unreviewed]RecName: Full=DNA-binding protein SATB {ECO:0000256|RuleBase:RU361129}; AltName: Full=Special AT-rich sequence-binding protein {ECO:0000256|RuleBase:RU361129};+++[F8WCV6_HUMAN|Unreviewed]SubName: Full=DNA-binding protein SATB2 {ECO:0000313|Ensembl:ENSP00000415610};+++[Q59FT3_HUMAN|Unreviewed]SubName: Full=SATB family member 2 variant {ECO:0000313|EMBL:BAD92613.1}; Flags: Fragment;"]
[23326,"'USP22'",5494,5828,5444,5588.66666666667,null,"H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016607///nuclear speck+++GO:0000124///SAGA complex+++GO:0005654///nucleoplasm+++GO:0070461///SAGA-type complex+++GO:0005634///nucleus","GO:0019899///enzyme binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0016787///hydrolase activity+++GO:0003713///transcription coactivator activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0006325///chromatin organization+++GO:0016574///histone ubiquitination+++GO:0007049///cell cycle+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016578///histone deubiquitination+++GO:0016579///protein deubiquitination+++GO:0043967///histone H4 acetylation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006508///proteolysis","ubiquitin specific peptidase 22","[UBP22_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 22; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 22; AltName: Full=Ubiquitin thioesterase 22; AltName: Full=Ubiquitin-specific-processing protease 22;+++[J3QRV6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 22 {ECO:0000313|Ensembl:ENSP00000464398};+++[J3QS30_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 22 {ECO:0000313|Ensembl:ENSP00000464499}; Flags: Fragment;+++[K7ERX6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 22 {ECO:0000313|Ensembl:ENSP00000468457}; Flags: Fragment;+++[K7ESK0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 22 {ECO:0000313|Ensembl:ENSP00000468748}; Flags: Fragment;"]
[23347,"'SMCHD1'",500,484,478,487.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016021///integral component of membrane+++GO:0035861///site of double-strand break+++GO:0005694///chromosome+++GO:0001740///Barr body+++GO:0016020///membrane+++GO:0000784///nuclear chromosome, telomeric region","GO:0016887///ATPase activity+++GO:0003677///DNA binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity","GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0006302///double-strand break repair+++GO:0043584///nose development+++GO:0045739///positive regulation of DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining+++GO:0051276///chromosome organization+++GO:0070868///heterochromatin organization involved in chromatin silencing+++GO:0006325///chromatin organization+++GO:0006281///DNA repair+++GO:0060821///inactivation of X chromosome by DNA methylation+++GO:0060820///inactivation of X chromosome by heterochromatin assembly+++GO:2000042///negative regulation of double-strand break repair via homologous recombination","structural maintenance of chromosomes flexible hinge domain containing 1","[SMHD1_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1 {ECO:0000250|UniProtKB:Q6P5D8}; Short=SMC hinge domain-containing protein 1 {ECO:0000250|UniProtKB:Q6P5D8}; EC=3.6.1.- {ECO:0000269|PubMed:29748383};+++[A0A2R8YCU7_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000493989}; Flags: Fragment;+++[A0A2R8YE92_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000495392}; Flags: Fragment;+++[J3KRK8_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000462050}; Flags: Fragment;+++[J3KTK7_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000463036}; Flags: Fragment;+++[J3KTL8_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000463049}; Flags: Fragment;+++[J3QSH1_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes flexible hinge domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000464684}; Flags: Fragment;+++[L0R6P7_HUMAN|Unreviewed]SubName: Full=Alternative protein SMCHD1 {ECO:0000313|EMBL:CCO13820.1};"]
[23371,"'TNS2'",393,460,398,417,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0030054///cell junction","GO:0019900///kinase binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0008285///negative regulation of cell proliferation+++GO:0032963///collagen metabolic process+++GO:0001822///kidney development+++GO:0048871///multicellular organismal homeostasis+++GO:0014850///response to muscle activity+++GO:0035264///multicellular organism growth+++GO:0019725///cellular homeostasis","tensin 2","[TNS2_HUMAN|Reviewed]RecName: Full=Tensin-2; EC=3.1.3.-; AltName: Full=C1 domain-containing phosphatase and tensin homolog; Short=C1-TEN; AltName: Full=Tensin-like C1 domain-containing phosphatase;+++[A0A024RB48_HUMAN|Unreviewed]SubName: Full=Tensin like C1 domain containing phosphatase (Tensin 2), isoform CRA_a {ECO:0000313|EMBL:EAW96660.1};+++[A7E2A6_HUMAN|Unreviewed]SubName: Full=Tensin like C1 domain containing phosphatase (Tensin 2) {ECO:0000313|EMBL:AAI50260.1};+++[F8VV64_HUMAN|Unreviewed]SubName: Full=Tensin-2 {ECO:0000313|Ensembl:ENSP00000449361};+++[H0YID7_HUMAN|Unreviewed]SubName: Full=Tensin-2 {ECO:0000313|Ensembl:ENSP00000449165}; Flags: Fragment;+++[R4GMX1_HUMAN|Unreviewed]SubName: Full=Tensin-2 {ECO:0000313|Ensembl:ENSP00000473388}; Flags: Fragment;"]
[23383,"'MAU2'",761,926,804,830.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0032116///SMC loading complex+++GO:0090694///Scc2-Scc4 cohesin loading complex+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0000785///chromatin","GO:0047485///protein N-terminus binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0007064///mitotic sister chromatid cohesion+++GO:0007059///chromosome segregation+++GO:0051301///cell division+++GO:0034088///maintenance of mitotic sister chromatid cohesion+++GO:0071921///cohesin loading","MAU2 sister chromatid cohesion factor","[SCC4_HUMAN|Reviewed]RecName: Full=MAU2 chromatid cohesion factor homolog; Short=MAU-2; AltName: Full=Cohesin loading complex subunit SCC4 homolog;+++[V9GYS3_HUMAN|Unreviewed]SubName: Full=MAU2 chromatid cohesion factor homolog {ECO:0000313|Ensembl:ENSP00000477034}; Flags: Fragment;+++[V9GZ52_HUMAN|Unreviewed]SubName: Full=MAU2 chromatid cohesion factor homolog {ECO:0000313|Ensembl:ENSP00000477436}; Flags: Fragment;"]
[23412,"'COMMD3'",295.74,308.28,338.72,314.246666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0006814///sodium ion transport+++GO:0043312///neutrophil degranulation+++GO:0006811///ion transport","COMM domain containing 3","[COMD3_HUMAN|Reviewed]RecName: Full=COMM domain-containing protein 3; AltName: Full=Protein Bup; AltName: Full=Protein PIL;+++[H0Y4E5_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000391237}; Flags: Fragment;+++[H0Y4W0_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000394580}; Flags: Fragment;+++[H0Y6Z9_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000408982}; Flags: Fragment;+++[Q6IB93_HUMAN|Unreviewed]SubName: Full=COMMD3 protein {ECO:0000313|EMBL:CAG33192.1};+++[R4GN06_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000473433}; Flags: Fragment;+++[R4GNF2_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000473624}; Flags: Fragment;"]
[2342,"'FNTB'",431.11,503.37,471,468.493333333333,"00900///Terpenoid backbone biosynthesis+++01130///Biosynthesis of antibiotics",null,null,"R09844///farnesyl-diphosphate:protein-cysteine farnesyltransferase   trans,trans-Farnesyl diphosphate + Protein-cysteine <=> S-Farnesyl protein + Diphosphate","GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex+++GO:0005965///protein farnesyltransferase complex","GO:0008270///zinc ion binding+++GO:0008144///drug binding+++GO:0042277///peptide binding+++GO:0004660///protein farnesyltransferase activity+++GO:0004311///farnesyltranstransferase activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity+++GO:0004659///prenyltransferase activity+++GO:0019840///isoprenoid binding+++GO:0005515///protein binding+++GO:0016740///transferase activity","GO:0018342///protein prenylation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0014070///response to organic cyclic compound+++GO:0042060///wound healing+++GO:0018343///protein farnesylation+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0034097///response to cytokine+++GO:0010035///response to inorganic substance+++GO:0008285///negative regulation of cell proliferation+++GO:0048145///regulation of fibroblast proliferation","farnesyltransferase, CAAX box, beta","[FNTB_HUMAN|Reviewed]RecName: Full=Protein farnesyltransferase subunit beta; Short=FTase-beta; EC=2.5.1.58; AltName: Full=CAAX farnesyltransferase subunit beta; AltName: Full=Ras proteins prenyltransferase subunit beta;"]
[23446,"'SLC44A1'",471.78,513,445,476.593333333333,"05231///Choline metabolism in cancer",{"$nulls":3},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane","GO:0015220///choline transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0015871///choline transport+++GO:0042426///choline catabolic process","solute carrier family 44 member 1","[CTL1_HUMAN|Reviewed]RecName: Full=Choline transporter-like protein 1; AltName: Full=CDw92; AltName: Full=Solute carrier family 44 member 1; AltName: CD_antigen=CD92;+++[A0A024R151_HUMAN|Unreviewed]SubName: Full=Solute carrier family 44, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW58996.1};"]
[23466,"'CBX6'",1983,2367,2045,2131.66666666667,{"$nulls":4},"GO:0009898///cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane+++GO:0030175///filopodium+++GO:0005694///chromosome+++GO:0043025///neuronal cell body+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0031519///PcG protein complex+++GO:0005654///nucleoplasm+++GO:0000792///heterochromatin+++GO:0005634///nucleus","GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0031175///neuron projection development","chromobox 6","[CBX6_HUMAN|Reviewed]RecName: Full=Chromobox protein homolog 6;+++[B0QXZ6_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 6 {ECO:0000313|Ensembl:ENSP00000216083};"]
[23500,"'DAAM2'",10342,12647,10251,11080,"04310///Wnt signaling pathway",{"$nulls":3},"GO:0070062///extracellular exosome","GO:0003779///actin binding+++GO:0017048///Rho GTPase binding+++GO:0005515///protein binding","GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000050///regulation of non-canonical Wnt signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0007368///determination of left/right symmetry+++GO:0016055///Wnt signaling pathway+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0016043///cellular component organization+++GO:0021516///dorsal spinal cord development","dishevelled associated activator of morphogenesis 2","[DAAM2_HUMAN|Reviewed]RecName: Full=Disheveled-associated activator of morphogenesis 2;+++[A0A0J9YX09_HUMAN|Unreviewed]SubName: Full=Disheveled-associated activator of morphogenesis 2 {ECO:0000313|Ensembl:ENSP00000488196};+++[A0A0J9YYF7_HUMAN|Unreviewed]SubName: Full=Disheveled-associated activator of morphogenesis 2 {ECO:0000313|Ensembl:ENSP00000488831}; SubName: Full=Dishevelled associated activator of morphogenesis 2, isoform CRA_a {ECO:0000313|EMBL:EAX03995.1};+++[F2Z2Q2_HUMAN|Unreviewed]SubName: Full=Disheveled-associated activator of morphogenesis 2 {ECO:0000313|Ensembl:ENSP00000384637};+++[Q6DCB0_HUMAN|Unreviewed]SubName: Full=DAAM2 protein {ECO:0000313|EMBL:AAH78153.1};"]
[23514,"'SPIDR'",666,752,712,710,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000228///nuclear chromosome","GO:0005515///protein binding","GO:0072757///cellular response to camptothecin+++GO:0070202///regulation of establishment of protein localization to chromosome+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:0031334///positive regulation of protein complex assembly+++GO:2000781///positive regulation of double-strand break repair+++GO:0006310///DNA recombination+++GO:0071479///cellular response to ionizing radiation+++GO:0000724///double-strand break repair via homologous recombination+++GO:0072711///cellular response to hydroxyurea+++GO:0010569///regulation of double-strand break repair via homologous recombination","scaffold protein involved in DNA repair","[SPIDR_HUMAN|Reviewed]RecName: Full=DNA repair-scaffolding protein; AltName: Full=Scaffolding protein involved in DNA repair;+++[B3KP42_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000427889}; SubName: Full=cDNA FLJ31118 fis, clone IMR322000656 {ECO:0000313|EMBL:BAG51554.1};+++[B4DMX9_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000429997}; SubName: Full=cDNA FLJ59936 {ECO:0000313|EMBL:BAG60041.1};+++[E5RFY2_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000427878}; Flags: Fragment;+++[E5RGV8_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000430965};+++[E5RGX8_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000430091}; Flags: Fragment;+++[E5RHG3_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000429805};+++[E5RIB8_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000429448};+++[E5RIU7_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000430664};+++[E5RJJ2_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000428222};+++[E7EVI9_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000430941};+++[H0YBC9_HUMAN|Unreviewed]SubName: Full=DNA repair-scaffolding protein {ECO:0000313|Ensembl:ENSP00000429193}; Flags: Fragment;"]
[2354,"'FOSB'",64,40,35,46.3333333333333,"05034///Alcoholism+++04657///IL-17 signaling pathway+++05031///Amphetamine addiction+++05030///Cocaine addiction+++04380///Osteoclast differentiation","H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus","GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding","GO:0032570///response to progesterone+++GO:0042493///response to drug+++GO:0009612///response to mechanical stimulus+++GO:0032870///cellular response to hormone stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0071277///cellular response to calcium ion+++GO:0051412///response to corticosterone+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007565///female pregnancy+++GO:0051591///response to cAMP+++GO:0043278///response to morphine+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","FosB proto-oncogene, AP-1 transcription factor subunit","[FOSB_HUMAN|Reviewed]RecName: Full=Protein fosB; AltName: Full=G0/G1 switch regulatory protein 3;+++[A0A024R0P6_HUMAN|Unreviewed]SubName: Full=FBJ murine osteosarcoma viral oncogene homolog B, isoform CRA_a {ECO:0000313|EMBL:EAW57352.1};+++[A1L186_HUMAN|Unreviewed]SubName: Full=FOSB protein {ECO:0000313|EMBL:AAI27826.1}; Flags: Fragment;+++[K7EJ89_HUMAN|Unreviewed]SubName: Full=Protein fosB {ECO:0000313|Ensembl:ENSP00000465068};+++[K7EKA0_HUMAN|Unreviewed]SubName: Full=Protein fosB {ECO:0000313|Ensembl:ENSP00000465528}; Flags: Fragment;+++[K7EKC1_HUMAN|Unreviewed]SubName: Full=Protein fosB {ECO:0000313|Ensembl:ENSP00000465552};+++[K7ERZ8_HUMAN|Unreviewed]SubName: Full=Protein fosB {ECO:0000313|Ensembl:ENSP00000468482};+++[Q6FGK6_HUMAN|Unreviewed]SubName: Full=FOSB protein {ECO:0000313|EMBL:CAG46898.1}; Flags: Fragment;"]
[23555,"'TSPAN15'",1756,1956,1737,1816.33333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0031902///late endosome membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0005788///endoplasmic reticulum lumen","GO:0005515///protein binding+++GO:0019899///enzyme binding","GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane+++GO:0008593///regulation of Notch signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0007166///cell surface receptor signaling pathway","tetraspanin 15","[TSN15_HUMAN|Reviewed]RecName: Full=Tetraspanin-15; Short=Tspan-15; AltName: Full=Tetraspan NET-7; AltName: Full=Transmembrane 4 superfamily member 15;+++[H7C285_HUMAN|Unreviewed]SubName: Full=Tetraspanin-15 {ECO:0000313|Ensembl:ENSP00000404528}; Flags: Fragment;"]
[23576,"'DDAH1'",3782,3026,2947,3251.66666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0016597///amino acid binding+++GO:0016403///dimethylargininase activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity","GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0006525///arginine metabolic process+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0045766///positive regulation of angiogenesis+++GO:0007263///nitric oxide mediated signal transduction+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0043116///negative regulation of vascular permeability+++GO:0006527///arginine catabolic process+++GO:1900038///negative regulation of cellular response to hypoxia+++GO:0000052///citrulline metabolic process+++GO:0008285///negative regulation of cell proliferation","dimethylarginine dimethylaminohydrolase 1","[DDAH1_HUMAN|Reviewed]RecName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase 1; Short=DDAH-1; Short=Dimethylarginine dimethylaminohydrolase 1; EC=3.5.3.18; AltName: Full=DDAHI; AltName: Full=Dimethylargininase-1;+++[B1AKK2_HUMAN|Unreviewed]SubName: Full=Dimethylarginine dimethylaminohydrolase 1, isoform CRA_b {ECO:0000313|EMBL:EAW73202.1}; SubName: Full=Epididymis secretory protein Li 16 {ECO:0000313|EMBL:ACJ13659.1}; SubName: Full=cDNA, FLJ92778, Homo sapiens dimethylarginine dimethylaminohydrolase 1 (DDAH1), mRNA {ECO:0000313|EMBL:BAG35341.1};+++[B4DGT0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54083, highly similar to NG,NG-dimethylarginine dimethylaminohydrolase 1 {ECO:0000313|EMBL:BAG57891.1};+++[B4DYP1_HUMAN|Unreviewed]SubName: Full=N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 {ECO:0000313|Ensembl:ENSP00000488725}; SubName: Full=cDNA FLJ54119, highly similar to NG,NG-dimethylarginine dimethylaminohydrolase 1 {ECO:0000313|EMBL:BAG63803.1};+++[B4E3V1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61209, highly similar to NG,NG-dimethylarginine dimethylaminohydrolase 1 {ECO:0000313|EMBL:BAG65613.1};"]
[23600,"'AMACR'",152,166,159,159,"04146///Peroxisome+++01100///Metabolic pathways+++00120///Primary bile acid biosynthesis","H02099///Alpha-methylacyl-CoA racemase deficiency+++H00628///Congenital bile acid synthesis defect (CBAS)+++H00407///Peroxisomal beta-oxidation enzyme deficiency","M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R08739///3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA 25-epimerase   (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA <=> (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R08734///3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA 25-epimerase   (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA <=> (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA","GO:0043231///intracellular membrane-bounded organelle+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix","GO:0016853///isomerase activity+++GO:0003824///catalytic activity+++GO:0005102///signaling receptor binding+++GO:0008111///alpha-methylacyl-CoA racemase activity","GO:0008206///bile acid metabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0006625///protein targeting to peroxisome+++GO:0006699///bile acid biosynthetic process+++GO:0006631///fatty acid metabolic process","alpha-methylacyl-CoA racemase","[AMACR_HUMAN|Reviewed]RecName: Full=Alpha-methylacyl-CoA racemase; EC=5.1.99.4; AltName: Full=2-methylacyl-CoA racemase;+++[A0A024RE16_HUMAN|Unreviewed]SubName: Full=Alpha-methylacyl-CoA racemase, isoform CRA_b {ECO:0000313|EMBL:EAX10817.1};+++[D6RB81_HUMAN|Unreviewed]SubName: Full=Alpha-methylacyl-CoA racemase {ECO:0000313|Ensembl:ENSP00000424351};+++[V9GYP4_HUMAN|Unreviewed]SubName: Full=Alpha-methylacyl-CoA racemase {ECO:0000313|Ensembl:ENSP00000476965};+++[V9GYU9_HUMAN|Unreviewed]SubName: Full=Alpha-methylacyl-CoA racemase {ECO:0000313|Ensembl:ENSP00000477108};+++[V9GZ45_HUMAN|Unreviewed]SubName: Full=Alpha-methylacyl-CoA racemase {ECO:0000313|Ensembl:ENSP00000477411};"]
[23630,"'KCNE5'",4,4,1,3,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0015459///potassium channel regulator activity+++GO:0044325///ion channel binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005515///protein binding+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization","GO:1901379///regulation of potassium ion transmembrane transport+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:2001257///regulation of cation channel activity+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0097623///potassium ion export across plasma membrane+++GO:0060048///cardiac muscle contraction+++GO:0086011///membrane repolarization during action potential+++GO:0060306///regulation of membrane repolarization+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:0086014///atrial cardiac muscle cell action potential+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0006811///ion transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0071805///potassium ion transmembrane transport+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0008016///regulation of heart contraction","potassium voltage-gated channel subfamily E regulatory subunit 5","[KCNE5_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E regulatory beta subunit 5; AltName: Full=AMME syndrome candidate gene 2 protein; AltName: Full=Potassium channel subunit beta MiRP4; AltName: Full=Potassium voltage-gated channel subfamily E member 1-like protein {ECO:0000303|PubMed:10493825};+++[Q2N1H9_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit 5 {ECO:0000313|EMBL:ABB00307.1}; Flags: Fragment;"]
[23654,"'PLXNB2'",26080,30725,27384,28063,"04360///Axon guidance",{"$nulls":3},"GO:0016020///membrane+++GO:0002116///semaphorin receptor complex+++GO:0009986///cell surface+++GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane","GO:0017154///semaphorin receptor activity+++GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process+++GO:0007162///negative regulation of cell adhesion+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:0050772///positive regulation of axonogenesis+++GO:0001932///regulation of protein phosphorylation+++GO:0010976///positive regulation of neuron projection development+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0043087///regulation of GTPase activity+++GO:0008360///regulation of cell shape+++GO:0007420///brain development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007405///neuroblast proliferation+++GO:0001843///neural tube closure+++GO:0030334///regulation of cell migration+++GO:2001222///regulation of neuron migration+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","plexin B2","[PLXB2_HUMAN|Reviewed]RecName: Full=Plexin-B2; AltName: Full=MM1; Flags: Precursor;+++[A0A087WU36_HUMAN|Unreviewed]SubName: Full=Plexin-B2 {ECO:0000313|Ensembl:ENSP00000478347};+++[A0A087X000_HUMAN|Unreviewed]SubName: Full=Plexin-B2 {ECO:0000313|Ensembl:ENSP00000482999};+++[A0PK02_HUMAN|Unreviewed]SubName: Full=PLXNB2 protein {ECO:0000313|EMBL:AAI27771.1};+++[A6QRG9_HUMAN|Unreviewed]SubName: Full=Plexin-B2 {ECO:0000313|Ensembl:ENSP00000400679}; Flags: Fragment;+++[A6QRH1_HUMAN|Unreviewed]SubName: Full=Plexin-B2 {ECO:0000313|Ensembl:ENSP00000387470}; Flags: Fragment;+++[E2PU09_HUMAN|Unreviewed]SubName: Full=Plexin-B2 {ECO:0000313|Ensembl:ENSP00000392620}; Flags: Fragment;+++[H0Y6J7_HUMAN|Unreviewed]SubName: Full=Plexin-B2 {ECO:0000313|Ensembl:ENSP00000406048}; Flags: Fragment;+++[H0Y7X5_HUMAN|Unreviewed]SubName: Full=Plexin-B2 {ECO:0000313|Ensembl:ENSP00000415757}; Flags: Fragment;+++[Q16293_HUMAN|Unreviewed]SubName: Full=Clone MM1 product {ECO:0000313|EMBL:AAB33781.1}; Flags: Fragment;+++[Q2TBE4_HUMAN|Unreviewed]SubName: Full=PLXNB2 protein {ECO:0000313|EMBL:AAI10367.1}; Flags: Fragment;+++[Q3LIB1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla00445 {ECO:0000313|EMBL:BAE45757.1}; Flags: Fragment;"]
[23708,"'GSPT2'",367,296,322,328.333333333333,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005575///cellular_component+++GO:0018444///translation release factor complex","GO:0005525///GTP binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0003723///RNA binding+++GO:0003747///translation release factor activity+++GO:0004364///glutathione transferase activity","GO:0002184///cytoplasmic translational termination+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0009636///response to toxic substance+++GO:0007049///cell cycle+++GO:0006412///translation","G1 to S phase transition 2","[ERF3B_HUMAN|Reviewed]RecName: Full=Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Short=Eukaryotic peptide chain release factor subunit 3b; Short=eRF3b; AltName: Full=G1 to S phase transition protein 2 homolog;+++[Q16605_HUMAN|Unreviewed]SubName: Full=GST2 protein {ECO:0000313|EMBL:AAA52617.1}; SubName: Full=Glutathione S-transferase {ECO:0000313|EMBL:AAA35938.1}; Flags: Fragment;"]
[23768,"'FLRT2'",2097,2247,2236,2193.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00255///Hypogonadotropic hypogonadism",null,null,"GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0005887///integral component of plasma membrane+++GO:0005911///cell-cell junction+++GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0043231///intracellular membrane-bounded organelle","GO:0005104///fibroblast growth factor receptor binding+++GO:0030674///protein binding, bridging+++GO:0045499///chemorepellent activity","GO:0051965///positive regulation of synapse assembly+++GO:0061343///cell adhesion involved in heart morphogenesis+++GO:0071711///basement membrane organization+++GO:2001222///regulation of neuron migration+++GO:0008150///biological_process+++GO:0007155///cell adhesion+++GO:0050919///negative chemotaxis+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0003007///heart morphogenesis","fibronectin leucine rich transmembrane protein 2","[FLRT2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat transmembrane protein FLRT2; AltName: Full=Fibronectin-like domain-containing leucine-rich transmembrane protein 2; Flags: Precursor;"]
[24137,"'KIF4A'",4,2,1,2.33333333333333,null,"H00658///Syndromic X-linked mental retardation+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)",null,null,"GO:0005654///nucleoplasm+++GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:0016363///nuclear matrix+++GO:0005876///spindle microtubule+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:1904115///axon cytoplasm+++GO:0016020///membrane","GO:0003677///DNA binding+++GO:0003774///motor activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0016887///ATPase activity","GO:0007052///mitotic spindle organization+++GO:0051256///mitotic spindle midzone assembly+++GO:0006996///organelle organization+++GO:0008089///anterograde axonal transport+++GO:0000281///mitotic cytokinesis+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0007018///microtubule-based movement+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER","kinesin family member 4A","[KIF4A_HUMAN|Reviewed]RecName: Full=Chromosome-associated kinesin KIF4A; AltName: Full=Chromokinesin-A;+++[Q59HG1_HUMAN|Unreviewed]SubName: Full=Chromosome-associated kinesin KIF4A variant {ECO:0000313|EMBL:BAD92034.1}; Flags: Fragment;+++[Q6PKB2_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394}; Flags: Fragment;"]
[246175,"'CNOT6L'",134,110,95,113,"03018///RNA degradation",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030014///CCR4-NOT complex+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0004518///nuclease activity+++GO:0004527///exonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0031047///gene silencing by RNA+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006417///regulation of translation+++GO:0006397///mRNA processing+++GO:0008284///positive regulation of cell proliferation+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0061157///mRNA destabilization+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening","CCR4-NOT transcription complex subunit 6 like","[CNO6L_HUMAN|Reviewed]RecName: Full=CCR4-NOT transcription complex subunit 6-like; EC=3.1.13.4; AltName: Full=Carbon catabolite repressor protein 4 homolog B;+++[B4E0K8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58660, highly similar to Mus musculus CCR4-NOT transcription complex, subunit 6-like (Cnot6l), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG64470.1};+++[D6RGK9_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 6-like {ECO:0000313|Ensembl:ENSP00000426269}; Flags: Fragment;+++[D6RIW9_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 6-like {ECO:0000313|Ensembl:ENSP00000425836};+++[H0Y9C1_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 6-like {ECO:0000313|Ensembl:ENSP00000423750}; Flags: Fragment;+++[H0Y9Z5_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 6-like {ECO:0000313|Ensembl:ENSP00000425571}; Flags: Fragment;+++[H0YA76_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 6-like {ECO:0000313|Ensembl:ENSP00000426320}; Flags: Fragment;"]
[2487,"'FRZB'",23901,30601,26302,26934.6666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0017147///Wnt-protein binding","GO:0061053///somite development+++GO:0001501///skeletal system development+++GO:0016055///Wnt signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0070367///negative regulation of hepatocyte differentiation+++GO:0030154///cell differentiation+++GO:0014033///neural crest cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0090103///cochlea morphogenesis+++GO:0010721///negative regulation of cell development+++GO:0042472///inner ear morphogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0060029///convergent extension involved in organogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0061037///negative regulation of cartilage development","frizzled related protein","[SFRP3_HUMAN|Reviewed]RecName: Full=Secreted frizzled-related protein 3; Short=sFRP-3; AltName: Full=Frezzled; AltName: Full=Fritz; AltName: Full=Frizzled-related protein 1; AltName: Full=FrzB-1; Flags: Precursor;+++[D9ZGF6_HUMAN|Unreviewed]SubName: Full=Frizzled-related protein {ECO:0000313|EMBL:ADL14515.1};+++[Q53QN4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein FRZB {ECO:0000313|EMBL:AAX93117.1}; Flags: Fragment;+++[Q53QT6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein FRZB {ECO:0000313|EMBL:AAY24241.1}; Flags: Fragment;"]
[2526,"'FUT4'",77,87,85.11,83.0366666666667,"01100///Metabolic pathways+++00515///Mannose type O-glycan biosynthesis+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,null,"R06222///GDP-L-fucose + G00084 <=> GDP + G00085+++R06227///GDP-L-fucose + G00081 <=> GDP + G00082+++R06075///GDP-L-fucose + Sialyl-3-paragloboside <=> GDP + IV3NeuAc,III3Fuc-nLc4Cer+++R06038///GDP-L-fucose + nLc6Cer <=> GDP + V3Fuc-nLc6Cer+++R06221///GDP-L-fucose + V3Fuc-nLc6Cer <=> GDP + V3Fuc,III3Fuc-nLc6Cer+++R06095///GDP-L-fucose + IV2Fuc-nLc4Cer <=> GDP + III3,IV2Fuc-nLc4Cer+++R06076///GDP-L-fucose + VI2Fuc-nLc6 <=> GDP + G00081+++R06224///GDP-L-fucose + G00085 <=> GDP + G00086+++R06039///GDP-L-fucose + nLc8Cer <=> GDP + G00084+++R06025///GDP-L-fucose + Paragloboside <=> GDP + III3Fuc-nLc4Cer+++R06230///GDP-L-fucose + nLc6Cer <=> GDP + III3Fuc-nLc6Cer","GO:0005794///Golgi apparatus+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane+++GO:0071944///cell periphery+++GO:0016021///integral component of membrane","GO:0008417///fucosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0046920///alpha-(1->3)-fucosyltransferase activity","GO:0005975///carbohydrate metabolic process+++GO:0036065///fucosylation+++GO:0042355///L-fucose catabolic process+++GO:0006486///protein glycosylation","fucosyltransferase 4","[FUT4_HUMAN|Reviewed]RecName: Full=Alpha-(1,3)-fucosyltransferase 4; EC=2.4.1.-; AltName: Full=ELAM-1 ligand fucosyltransferase; AltName: Full=Fucosyltransferase 4; AltName: Full=Fucosyltransferase IV; Short=Fuc-TIV; Short=FucT-IV; AltName: Full=Galactoside 3-L-fucosyltransferase;"]
[253461,"'ZBTB38'",1098,1330,1079,1169,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0072562///blood microparticle+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008327///methyl-CpG binding+++GO:0042803///protein homodimerization activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006275///regulation of DNA replication+++GO:0045944///positive regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 38","[ZBT38_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 38;+++[A0A1B0GV48_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000490370}; Flags: Fragment;+++[D6R9I1_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422081}; Flags: Fragment;+++[D6R9J6_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422051}; Flags: Fragment;+++[D6R9U6_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422894}; Flags: Fragment;+++[D6RAC4_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422757}; Flags: Fragment;+++[D6RBC4_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000424254}; Flags: Fragment;+++[D6RC86_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000422347}; Flags: Fragment;+++[D6RE69_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426931}; Flags: Fragment;+++[D6RGK1_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000426288}; Flags: Fragment;+++[D6RHD1_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000421037}; Flags: Fragment;+++[D6RJE1_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 38 {ECO:0000313|Ensembl:ENSP00000425705}; Flags: Fragment;+++[Q32Q70_HUMAN|Unreviewed]SubName: Full=ZBTB38 protein {ECO:0000313|EMBL:AAI07746.1}; Flags: Fragment;+++[Q9H6F0_HUMAN|Unreviewed]SubName: Full=cDNA: FLJ22332 fis, clone HRC05753 {ECO:0000313|EMBL:BAB15309.1};"]
[253782,"'CERS6'",1286,1222,1151,1219.66666666667,"00600///Sphingolipid metabolism+++01100///Metabolic pathways+++04071///Sphingolipid signaling pathway","H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H00734///Autosomal recessive congenital ichthyosis","M00094///Ceramide biosynthesis+++M00099///Sphingosine biosynthesis","R01496///acyl-CoA:sphingosine N-acyltransferase   Acyl-CoA + Sphingosine <=> CoA + N-Acylsphingosine+++R06517///acyl-CoA:sphingosine N-acyltransferase   Acyl-CoA + Sphinganine <=> CoA + Dihydroceramide","GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0016740///transferase activity+++GO:0050291///sphingosine N-acyltransferase activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046513///ceramide biosynthetic process","ceramide synthase 6","[CERS6_HUMAN|Reviewed]RecName: Full=Ceramide synthase 6; Short=CerS6; AltName: Full=LAG1 longevity assurance homolog 6;+++[B4DQR7_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000407896}; SubName: Full=cDNA FLJ59959, moderately similar to LAG1 longevity assurance homolog 5 {ECO:0000313|EMBL:BAG61029.1};+++[F8VQZ6_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000450072};+++[F8VSK7_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000448257};+++[F8VXY1_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000448794};+++[F8VY42_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000448755};+++[F8W1K4_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000446937};+++[F8W1N7_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000446931};+++[F8W1Z3_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000447410};+++[H0YHG4_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000447029}; Flags: Fragment;+++[H0YHK2_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000447266}; Flags: Fragment;+++[H0YI10_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000448295}; Flags: Fragment;+++[H0YIG1_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000449311}; Flags: Fragment;+++[Q49AQ3_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 5 {ECO:0000313|Ensembl:ENSP00000369536}; SubName: Full=LASS5 protein {ECO:0000313|EMBL:AAH33558.1};"]
[253959,"'RALGAPA1'",408.96,475.97,406,430.31,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0005096///GTPase activator activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity+++GO:0043547///positive regulation of GTPase activity","Ral GTPase activating protein catalytic alpha subunit 1","[RGPA1_HUMAN|Reviewed]RecName: Full=Ral GTPase-activating protein subunit alpha-1; AltName: Full=GAP-related-interacting partner to E12; Short=GRIPE; AltName: Full=GTPase-activating Rap/Ran-GAP domain-like 1; AltName: Full=Tuberin-like protein 1; AltName: Full=p240;+++[A0A1B0GUI1_HUMAN|Unreviewed]SubName: Full=Ral GTPase-activating protein subunit alpha-1 {ECO:0000313|Ensembl:ENSP00000490119};+++[A0PJ59_HUMAN|Unreviewed]SubName: Full=GARNL1 protein {ECO:0000313|EMBL:AAH16305.1}; Flags: Fragment;+++[H0YJ04_HUMAN|Unreviewed]SubName: Full=Ral GTPase-activating protein subunit alpha-1 {ECO:0000313|Ensembl:ENSP00000450574}; Flags: Fragment;+++[H0YJB5_HUMAN|Unreviewed]SubName: Full=Ral GTPase-activating protein subunit alpha-1 {ECO:0000313|Ensembl:ENSP00000451133}; Flags: Fragment;+++[L8EAR6_HUMAN|Unreviewed]SubName: Full=Alternative protein RALGAPA1 {ECO:0000313|EMBL:CCQ43478.1};"]
[254778,"'VXN'",49,37,48,44.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane",null,"GO:0007399///nervous system development+++GO:0022008///neurogenesis+++GO:0030182///neuron differentiation","vexin","[VEXIN_HUMAN|Reviewed]RecName: Full=Vexin {ECO:0000250|UniProtKB:Q8BG31};+++[E5RH60_HUMAN|Unreviewed]SubName: Full=Vexin {ECO:0000313|Ensembl:ENSP00000429883};+++[E5RJS6_HUMAN|Unreviewed]SubName: Full=Vexin {ECO:0000313|Ensembl:ENSP00000430501};+++[E5RKA6_HUMAN|Unreviewed]SubName: Full=Vexin {ECO:0000313|Ensembl:ENSP00000430388};+++[R4GNJ7_HUMAN|Unreviewed]SubName: Full=Vexin {ECO:0000313|Ensembl:ENSP00000473681};"]
[255119,"'CFAP299'",1,1,0,0.666666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","cilia and flagella associated protein 299","[CF299_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 299 {ECO:0000305};+++[A0A087WX50_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 299 {ECO:0000313|Ensembl:ENSP00000480723};+++[E7EPK2_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 299 {ECO:0000313|Ensembl:ENSP00000426308};+++[G5E9Y8_HUMAN|Unreviewed]SubName: Full=Cilia and flagella-associated protein 299 {ECO:0000313|Ensembl:ENSP00000422569};"]
[255308,"'EIF2S3B'",0,1.04,0,0.346666666666667,"03013///RNA transport","H00658///Syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005850///eukaryotic translation initiation factor 2 complex+++GO:0005829///cytosol","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity","GO:0006413///translational initiation+++GO:0006412///translation+++GO:0001731///formation of translation preinitiation complex","eukaryotic translation initiation factor 2 subunit gamma B","[IF2GL_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 2 subunit 3B {ECO:0000305}; AltName: Full=Eukaryotic translation initiation factor 2 subunit gamma A; Short=eIF-2-gamma A {ECO:0000303|PubMed:9736774}; Short=eIF-2gA;"]
[256051,"'ZNF549'",105,114,96,105,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 549","[ZN549_HUMAN|Reviewed]RecName: Full=Zinc finger protein 549;+++[M0QXN3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 549 {ECO:0000313|Ensembl:ENSP00000469280};+++[M0R0L6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 549 {ECO:0000313|Ensembl:ENSP00000471315};"]
[2563,"'GABRD'",0,4,4,2.66666666666667,"05032///Morphine addiction+++04727///GABAergic synapse+++04080///Neuroactive ligand-receptor interaction+++05033///Nicotine addiction+++04723///Retrograde endocannabinoid signaling","H00783///Febrile seizures",null,null,"GO:0005886///plasma membrane+++GO:0098982///GABA-ergic synapse+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045211///postsynaptic membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0034707///chloride channel complex+++GO:0043005///neuron projection+++GO:0099055///integral component of postsynaptic membrane+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:1902711///GABA-A receptor complex","GO:0004890///GABA-A receptor activity+++GO:0005254///chloride channel activity+++GO:0005216///ion channel activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005230///extracellular ligand-gated ion channel activity","GO:0060078///regulation of postsynaptic membrane potential+++GO:0006811///ion transport+++GO:0042391///regulation of membrane potential+++GO:0007268///chemical synaptic transmission+++GO:0050877///nervous system process+++GO:1902476///chloride transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0006821///chloride transport+++GO:0007165///signal transduction","gamma-aminobutyric acid type A receptor delta subunit","[GBRD_HUMAN|Reviewed]RecName: Full=Gamma-aminobutyric acid receptor subunit delta; AltName: Full=GABA(A) receptor subunit delta; Flags: Precursor;+++[A0A1W2PP88_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000491287}; Flags: Fragment;+++[A0A1W2PPH3_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000491411}; Flags: Fragment;+++[A0A1W2PPP1_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000491632}; Flags: Fragment;+++[A0A1W2PQR3_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000491844};+++[A0A1W2PQT2_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000491871}; Flags: Fragment;+++[A0A1W2PQZ5_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000491997};+++[A0A1W2PR72_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000492352}; Flags: Fragment;+++[A0A1W2PRC4_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000492435};+++[A0A1W2PRY7_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit delta {ECO:0000313|Ensembl:ENSP00000492500};+++[A8K496_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75677, highly similar to Homo sapiens gamma-aminobutyric acid (GABA) A receptor, delta (GABRD), mRNA {ECO:0000313|EMBL:BAF83550.1};"]
[256987,"'SERINC5'",138,145,160,147.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043209///myelin sheath+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0015194///L-serine transmembrane transporter activity","GO:0006564///L-serine biosynthetic process+++GO:0051607///defense response to virus+++GO:0006658///phosphatidylserine metabolic process+++GO:0015825///L-serine transport+++GO:0045087///innate immune response+++GO:0016032///viral process+++GO:0008654///phospholipid biosynthetic process+++GO:0042552///myelination+++GO:1904219///positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0009597///detection of virus+++GO:0006665///sphingolipid metabolic process+++GO:0002376///immune system process+++GO:1904222///positive regulation of serine C-palmitoyltransferase activity+++GO:0006629///lipid metabolic process","serine incorporator 5","[SERC5_HUMAN|Reviewed]RecName: Full=Serine incorporator 5 {ECO:0000305};+++[A0A0J9YYI4_HUMAN|Unreviewed]SubName: Full=Serine incorporator 5 {ECO:0000313|Ensembl:ENSP00000488864};"]
[257397,"'TAB3'",545,625,628,599.333333333333,"04657///IL-17 signaling pathway+++04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway+++04064///NF-kappa B signaling pathway",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0000187///activation of MAPK activity+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0007254///JNK cascade+++GO:0010507///negative regulation of autophagy+++GO:0070498///interleukin-1-mediated signaling pathway","TGF-beta activated kinase 1 (MAP3K7) binding protein 3","[TAB3_HUMAN|Reviewed]RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 3; AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 3; AltName: Full=NF-kappa-B-activating protein 1; AltName: Full=TAK1-binding protein 3; Short=TAB-3; AltName: Full=TGF-beta-activated kinase 1-binding protein 3;+++[A0A0A0MQY2_HUMAN|Unreviewed]SubName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 {ECO:0000313|Ensembl:ENSP00000288422}; Flags: Fragment;+++[F6SS63_HUMAN|Unreviewed]SubName: Full=TAK1-binding protein 3, isoform CRA_c {ECO:0000313|EMBL:EAW99059.1}; SubName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 {ECO:0000313|Ensembl:ENSP00000433193};"]
[25775,"'C22orf24'",0,4,6,3.33333333333333,"04110///Cell cycle+++05169///Epstein-Barr virus infection+++04390///Hippo signaling pathway+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++04114///Oocyte meiosis","H00606///Early infantile epileptic encephalopathy",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding+++GO:0019899///enzyme binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0035259///glucocorticoid receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0017080///sodium channel regulator activity+++GO:0044325///ion channel binding+++GO:0019904///protein domain specific binding+++GO:0003779///actin binding","GO:0086010///membrane depolarization during action potential+++GO:0048167///regulation of synaptic plasticity+++GO:2000649///regulation of sodium ion transmembrane transporter activity+++GO:0002028///regulation of sodium ion transport+++GO:0006886///intracellular protein transport+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0006713///glucocorticoid catabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0061024///membrane organization+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0021762///substantia nigra development+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0045664///regulation of neuron differentiation","chromosome 22 open reading frame 24","[CV024_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C22orf24;+++[B7Z221_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55838 {ECO:0000313|EMBL:BAH11707.1};"]
[25789,"'TMEM59L'",419,402,408,409.666666666667,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus",null,null,"transmembrane protein 59 like","[TM59L_HUMAN|Reviewed]RecName: Full=Transmembrane protein 59-like; AltName: Full=Brain-specific membrane-anchored protein; Flags: Precursor;+++[A0A024R7L4_HUMAN|Unreviewed]SubName: Full=Chromosome 19 open reading frame 4, isoform CRA_a {ECO:0000313|EMBL:EAW84727.1};+++[M0R134_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 59-like {ECO:0000313|Ensembl:ENSP00000471612}; Flags: Fragment;"]
[25818,"'KLK5'",36,21,22,26.3333333333333,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0030141///secretory granule+++GO:0005576///extracellular region+++GO:0097209///epidermal lamellar body","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0004175///endopeptidase activity+++GO:0008233///peptidase activity","GO:0022617///extracellular matrix disassembly+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0006508///proteolysis+++GO:0097186///amelogenesis+++GO:0002803///positive regulation of antibacterial peptide production+++GO:0070268///cornification+++GO:0008544///epidermis development","kallikrein related peptidase 5","[KLK5_HUMAN|Reviewed]RecName: Full=Kallikrein-5 {ECO:0000312|HGNC:HGNC:6366}; EC=3.4.21.-; AltName: Full=Kallikrein-like protein 2; Short=KLK-L2; AltName: Full=Stratum corneum tryptic enzyme; Flags: Precursor;+++[A0A2I2MP48_HUMAN|Unreviewed]SubName: Full=Kallikrein-related peptidase 5 transcript variant 5 {ECO:0000313|EMBL:AQR57578.1};+++[A0A2I2MP49_HUMAN|Unreviewed]SubName: Full=Kallikrein-related peptidase 5 transcript variant 6 {ECO:0000313|EMBL:AQR57579.1};+++[M0QXX2_HUMAN|Unreviewed]SubName: Full=Kallikrein-5 {ECO:0000313|Ensembl:ENSP00000469439}; Flags: Fragment;+++[Q6S9W8_HUMAN|Unreviewed]SubName: Full=Kallikrein 5 isoform 3 preproprotein {ECO:0000313|EMBL:AAR23814.1}; SubName: Full=Kallikrein 5, isoform CRA_b {ECO:0000313|EMBL:EAW71947.1};"]
[25823,"'TPSG1'",0,1,2,1,"04020///Calcium signaling pathway+++04010///MAPK signaling pathway+++04934///Cushing's syndrome+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04713///Circadian entrainment","H01603///Primary aldosteronism+++H00808///Idiopathic generalized epilepsies (IGEs)",null,null,"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0004834///tryptophan synthase activity+++GO:0003824///catalytic activity+++GO:0008236///serine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0016829///lyase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity","GO:0006508///proteolysis+++GO:0006568///tryptophan metabolic process+++GO:0000162///tryptophan biosynthetic process","tryptase gamma 1","[TRYG1_HUMAN|Reviewed]RecName: Full=Tryptase gamma; EC=3.4.21.-; AltName: Full=Serine protease 31; AltName: Full=Transmembrane tryptase; Contains: RecName: Full=Tryptase gamma light chain; Contains: RecName: Full=Tryptase gamma heavy chain; Flags: Precursor;+++[A0A2P9ABH7_HUMAN|Unreviewed]SubName: Full=Tryptophan synthase alpha chain {ECO:0000313|EMBL:SJM28495.1}; EC=4.2.1.20 {ECO:0000313|EMBL:SJM28495.1};+++[L8EAM4_HUMAN|Unreviewed]SubName: Full=Alternative protein TPSG1 {ECO:0000313|EMBL:CCQ43413.1};"]
[25840,"'METTL7A'",28,34,32,31.3333333333333,{"$nulls":4},"GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:1904724///tertiary granule lumen+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region","GO:0008168///methyltransferase activity+++GO:0016740///transferase activity","GO:0032259///methylation+++GO:0043312///neutrophil degranulation","methyltransferase like 7A","[MET7A_HUMAN|Reviewed]RecName: Full=Methyltransferase-like protein 7A; EC=2.1.1.-; AltName: Full=Protein AAM-B; Flags: Precursor;+++[A0A024R118_HUMAN|Unreviewed]SubName: Full=Methyltransferase like 7A, isoform CRA_a {ECO:0000313|EMBL:EAW58155.1};+++[F8VQX6_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 7A {ECO:0000313|Ensembl:ENSP00000450239}; Flags: Fragment;+++[H0YI09_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 7A {ECO:0000313|Ensembl:ENSP00000448286}; Flags: Fragment;"]
[2588,"'GALNS'",926,910,906,914,"04142///Lysosome+++00531///Glycosaminoglycan degradation+++01100///Metabolic pathways","H00421///Mucopolysaccharidosis (MPS)+++H00123///Mucopolysaccharidosis type IV (MPS4)","M00077///Chondroitin sulfate degradation+++M00079///Keratan sulfate degradation","R07806///N-acetyl-D-galactosamine 6-sulfate 6-sulfohydrolase   G01945 + H2O <=> G01977 + Sulfate","GO:0005576///extracellular region+++GO:0043202///lysosomal lumen+++GO:0035578///azurophil granule lumen+++GO:0005764///lysosome+++GO:0070062///extracellular exosome","GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0043890///N-acetylgalactosamine-6-sulfatase activity+++GO:0003943///N-acetylgalactosamine-4-sulfatase activity+++GO:0008484///sulfuric ester hydrolase activity","GO:0042340///keratan sulfate catabolic process+++GO:0043312///neutrophil degranulation","galactosamine (N-acetyl)-6-sulfatase","[GALNS_HUMAN|Reviewed]RecName: Full=N-acetylgalactosamine-6-sulfatase; EC=3.1.6.4; AltName: Full=Chondroitinsulfatase; Short=Chondroitinase; AltName: Full=Galactose-6-sulfate sulfatase; Short=GalN6S; AltName: Full=N-acetylgalactosamine-6-sulfate sulfatase; Short=GalNAc6S sulfatase; Flags: Precursor;+++[A0A1A7UP97_HUMAN|Unreviewed]SubName: Full=Galactosamine (N-acetyl)-6-sulfatase {ECO:0000313|EMBL:SBN37597.1};+++[A0A286S6D8_HUMAN|Unreviewed]SubName: Full=Galactosamine (N-acetyl)-6-sulfatase {ECO:0000313|EMBL:ASY06631.1}; Flags: Fragment;+++[A0A2I6U1L6_HUMAN|Unreviewed]SubName: Full=Galactosamine (N-acetyl)-6-sulfatase {ECO:0000313|EMBL:AUO68209.1}; Flags: Fragment;+++[H3BNU2_HUMAN|Unreviewed]SubName: Full=N-acetylgalactosamine-6-sulfatase {ECO:0000313|Ensembl:ENSP00000455006};+++[H3BP66_HUMAN|Unreviewed]SubName: Full=N-acetylgalactosamine-6-sulfatase {ECO:0000313|Ensembl:ENSP00000455174}; Flags: Fragment;+++[H3BSU9_HUMAN|Unreviewed]SubName: Full=N-acetylgalactosamine-6-sulfatase {ECO:0000313|Ensembl:ENSP00000456884};+++[H3BV24_HUMAN|Unreviewed]SubName: Full=N-acetylgalactosamine-6-sulfatase {ECO:0000313|Ensembl:ENSP00000457921}; Flags: Fragment;+++[Q6MZF5_HUMAN|Unreviewed]SubName: Full=N-acetylgalactosamine-6-sulfatase {ECO:0000313|Ensembl:ENSP00000454484}; Flags: Fragment;+++[Q6YL38_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAM98764.1};+++[Q96I49_HUMAN|Unreviewed]SubName: Full=GALNS protein {ECO:0000313|EMBL:AAH07825.2}; Flags: Fragment;"]
[25886,"'POC1A'",41,35,32,36,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0005814///centriole+++GO:0036064///ciliary basal body+++GO:0005737///cytoplasm+++GO:0000922///spindle pole+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:1905515///non-motile cilium assembly+++GO:0010825///positive regulation of centrosome duplication+++GO:0003431///growth plate cartilage chondrocyte development+++GO:0060348///bone development+++GO:0030030///cell projection organization+++GO:0007283///spermatogenesis+++GO:0007052///mitotic spindle organization","POC1 centriolar protein A","[POC1A_HUMAN|Reviewed]RecName: Full=POC1 centriolar protein homolog A; AltName: Full=Pix2; AltName: Full=Proteome of centriole protein 1A; AltName: Full=WD repeat-containing protein 51A;"]
[25900,"'IFFO1'",343,389,365,365.666666666667,"04111///Cell cycle - yeast","H01673///Palmoplantar keratoderma+++H00693///Ichthyosis bullosa of Siemens+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00944///Dowling-Degos disease+++H00667///Woolly hair+++H00724///White sponge nevus+++H00649///Ectodermal dysplasia, pure hair-nail type (HNED)+++H00584///Epidermolysis bullosa simplex+++H00707///Ichthyosis hystrix, Curth-Macklin type+++H00786///Hereditary hypotrichosis simplex+++H00672///Pseudofolliculitis barbae+++H00717///Striate palmoplantar keratoderma+++H00670///Monilethrix+++H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H00726///Meesmann corneal dystrophy+++H00684///Pachyonychia congenita",null,null,"GO:0005882///intermediate filament","GO:0005198///structural molecule activity","GO:0051304///chromosome separation+++GO:0007076///mitotic chromosome condensation+++GO:0051301///cell division+++GO:0010032///meiotic chromosome condensation","intermediate filament family orphan 1","[IFFO1_HUMAN|Reviewed]RecName: Full=Intermediate filament family orphan 1; AltName: Full=Tumor antigen HOM-TES-103;+++[A0A087WZ16_HUMAN|Unreviewed]SubName: Full=Intermediate filament family orphan 1 {ECO:0000313|Ensembl:ENSP00000482285};+++[B4DQQ1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55827 {ECO:0000313|EMBL:BAG61013.1};+++[D3DUR5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW88784.1};+++[E9PPX7_HUMAN|Unreviewed]SubName: Full=Intermediate filament family orphan 1 {ECO:0000313|Ensembl:ENSP00000436261};+++[F8W8H2_HUMAN|Unreviewed]SubName: Full=Intermediate filament family orphan 1 {ECO:0000313|Ensembl:ENSP00000390721};+++[Q6P593_HUMAN|Unreviewed]SubName: Full=IFFO1 protein {ECO:0000313|EMBL:AAH63004.1};+++[Q9Y4M3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp586I2223 {ECO:0000313|EMBL:CAB45778.1}; Flags: Fragment;"]
[25921,"'ZDHHC5'",2179,2172,2104,2151.66666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite","GO:0016409///palmitoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0018345///protein palmitoylation","zinc finger DHHC-type containing 5","[ZDHC5_HUMAN|Reviewed]RecName: Full=Palmitoyltransferase ZDHHC5; EC=2.3.1.225; AltName: Full=Zinc finger DHHC domain-containing protein 5; Short=DHHC-5; AltName: Full=Zinc finger protein 375;+++[A0A024R546_HUMAN|Unreviewed]RecName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119}; EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119};+++[E9PJ97_HUMAN|Unreviewed]RecName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119}; EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119}; Flags: Fragment;+++[E9PMA5_HUMAN|Unreviewed]RecName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119}; EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119}; Flags: Fragment;+++[H0YEF4_HUMAN|Unreviewed]SubName: Full=Palmitoyltransferase ZDHHC5 {ECO:0000313|Ensembl:ENSP00000435722}; Flags: Fragment;"]
[259290,"'TAS2R31'",2,0,1,1,"04742///Taste transduction","H01611///Alcohol dependence",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0033038///bitter taste receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus+++GO:0050909///sensory perception of taste+++GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0007165///signal transduction","taste 2 receptor member 31","[T2R31_HUMAN|Reviewed]RecName: Full=Taste receptor type 2 member 31; Short=T2R31; AltName: Full=Taste receptor type 2 member 44; Short=T2R44; AltName: Full=Taste receptor type 2 member 53; Short=T2R53;+++[A0A0J9YWB3_HUMAN|Unreviewed]RecName: Full=Taste receptor type 2 {ECO:0000256|RuleBase:RU004424};"]
[25942,"'SIN3A'",664,725,621,670,"05202///Transcriptional misregulation in cancer+++05016///Huntington's disease+++04919///Thyroid hormone signaling pathway+++04139///Mitophagy - yeast","H01861///Chromosome 15q24 microdeletion syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0000785///chromatin+++GO:0005730///nucleolus+++GO:0005667///transcription factor complex+++GO:0017053///transcriptional repressor complex+++GO:0032991///protein-containing complex+++GO:0016580///Sin3 complex+++GO:0005634///nucleus+++GO:0000776///kinetochore","GO:0003714///transcription corepressor activity+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0044877///protein-containing complex binding+++GO:0004407///histone deacetylase activity+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0033558///protein deacetylase activity+++GO:0008134///transcription factor binding","GO:0002230///positive regulation of defense response to virus by host+++GO:0016575///histone deacetylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:1900181///negative regulation of protein localization to nucleus+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0031937///positive regulation of chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006476///protein deacetylation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0051595///response to methylglyoxal+++GO:1903351///cellular response to dopamine+++GO:0002218///activation of innate immune response+++GO:0006260///DNA replication+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0034613///cellular protein localization+++GO:0043066///negative regulation of apoptotic process+++GO:0007568///aging+++GO:0001701///in utero embryonic development+++GO:0010243///response to organonitrogen compound+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0048511///rhythmic process+++GO:0071333///cellular response to glucose stimulus+++GO:1901675///negative regulation of histone H3-K27 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010817///regulation of hormone levels+++GO:0019216///regulation of lipid metabolic process+++GO:0042754///negative regulation of circadian rhythm","SIN3 transcription regulator family member A","[SIN3A_HUMAN|Reviewed]RecName: Full=Paired amphipathic helix protein Sin3a; AltName: Full=Histone deacetylase complex subunit Sin3a; AltName: Full=Transcriptional corepressor Sin3a;+++[H3BMA2_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000454296}; Flags: Fragment;+++[H3BNA0_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000454750}; Flags: Fragment;+++[H3BNZ3_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000455072}; Flags: Fragment;+++[H3BP90_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000455204}; Flags: Fragment;+++[H3BQ76_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000455644}; Flags: Fragment;+++[H3BQ88_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000455662}; Flags: Fragment;+++[H3BQL7_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000455834};+++[H3BT34_HUMAN|Unreviewed]SubName: Full=Paired amphipathic helix protein Sin3a {ECO:0000313|Ensembl:ENSP00000456997}; Flags: Fragment;"]
[25966,"'C2CD2'",116,104,121,113.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane",null,null,"C2 calcium dependent domain containing 2","[C2CD2_HUMAN|Reviewed]RecName: Full=C2 domain-containing protein 2; AltName: Full=Transmembrane protein 24-like;+++[H7BZB0_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000388704}; Flags: Fragment;+++[Q6P6D1_HUMAN|Unreviewed]SubName: Full=C2CD2 protein {ECO:0000313|EMBL:AAH62323.1};"]
[25988,"'HINFP'",190,224,208,207.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015030///Cajal body+++GO:0005730///nucleolus","GO:0003676///nucleic acid binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0042393///histone binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0000077///DNA damage checkpoint+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0045445///myoblast differentiation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0010629///negative regulation of gene expression+++GO:0001701///in utero embryonic development+++GO:0010468///regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006281///DNA repair+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0045184///establishment of protein localization+++GO:0045893///positive regulation of transcription, DNA-templated","histone H4 transcription factor","[HINFP_HUMAN|Reviewed]RecName: Full=Histone H4 transcription factor; AltName: Full=Histone nuclear factor P; Short=HiNF-P; AltName: Full=MBD2-interacting zinc finger protein; AltName: Full=Methyl-CpG-binding protein 2-interacting zinc finger protein;+++[A0A024R3F5_HUMAN|Unreviewed]SubName: Full=MBD2-interacting zinc finger, isoform CRA_b {ECO:0000313|EMBL:EAW67462.1};+++[E9PJA3_HUMAN|Unreviewed]SubName: Full=Histone H4 transcription factor {ECO:0000313|Ensembl:ENSP00000433836}; Flags: Fragment;+++[E9PL67_HUMAN|Unreviewed]SubName: Full=Histone H4 transcription factor {ECO:0000313|Ensembl:ENSP00000431468}; Flags: Fragment;"]
[26011,"'TENM4'",867,939,978,928,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0050839///cell adhesion molecule binding","GO:0031641///regulation of myelination+++GO:0031643///positive regulation of myelination+++GO:0060912///cardiac cell fate specification+++GO:0060038///cardiac muscle cell proliferation+++GO:0007275///multicellular organism development+++GO:2000543///positive regulation of gastrulation+++GO:0007165///signal transduction+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0048666///neuron development+++GO:0030154///cell differentiation+++GO:0032289///central nervous system myelin formation+++GO:0001702///gastrulation with mouth forming second+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules","teneurin transmembrane protein 4","[TEN4_HUMAN|Reviewed]RecName: Full=Teneurin-4; Short=Ten-4; AltName: Full=Protein Odd Oz/ten-m homolog 4; AltName: Full=Tenascin-M4; Short=Ten-m4; AltName: Full=Teneurin transmembrane protein 4;+++[A0A0S2PZP6_HUMAN|Unreviewed]SubName: Full=Teneurin transmembrane protein 4 {ECO:0000313|EMBL:ALP06226.1}; Flags: Fragment;+++[E9PPG4_HUMAN|Unreviewed]SubName: Full=Teneurin-4 {ECO:0000313|Ensembl:ENSP00000432705}; Flags: Fragment;+++[G3CAT1_HUMAN|Unreviewed]SubName: Full=Odz, odd Oz/ten-m homolog 4 (Drosophila) {ECO:0000313|EMBL:CCD17870.1}; Flags: Fragment;+++[G3CAT2_HUMAN|Unreviewed]SubName: Full=Odz, odd Oz/ten-m homolog 4 (Drosophila) {ECO:0000313|EMBL:CCD17871.1}; Flags: Fragment;+++[G4VTY1_HUMAN|Unreviewed]SubName: Full=Teneurin-4 {ECO:0000313|EMBL:CCE12274.1}; Flags: Fragment;+++[H0YCJ4_HUMAN|Unreviewed]SubName: Full=Teneurin-4 {ECO:0000313|Ensembl:ENSP00000431711}; Flags: Fragment;+++[H0YCW4_HUMAN|Unreviewed]SubName: Full=Teneurin-4 {ECO:0000313|Ensembl:ENSP00000432427}; Flags: Fragment;+++[L8EC75_HUMAN|Unreviewed]SubName: Full=Alternative protein ODZ4 {ECO:0000313|EMBL:CCQ43077.1};"]
[26033,"'ATRNL1'",824,744,609,725.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0007186///G protein-coupled receptor signaling pathway","attractin like 1","[ATRN1_HUMAN|Reviewed]RecName: Full=Attractin-like protein 1; Flags: Precursor;+++[A0A087X0X7_HUMAN|Unreviewed]SubName: Full=Attractin-like protein 1 {ECO:0000313|Ensembl:ENSP00000483722};+++[E9PL90_HUMAN|Unreviewed]SubName: Full=Attractin-like protein 1 {ECO:0000313|Ensembl:ENSP00000431423}; Flags: Fragment;+++[H0YDQ9_HUMAN|Unreviewed]SubName: Full=Attractin-like protein 1 {ECO:0000313|Ensembl:ENSP00000434118}; Flags: Fragment;+++[Q4G0Y2_HUMAN|Unreviewed]SubName: Full=ATRNL1 protein {ECO:0000313|EMBL:AAH35157.1};+++[R4GMZ1_HUMAN|Unreviewed]SubName: Full=Attractin-like protein 1 {ECO:0000313|Ensembl:ENSP00000473412};"]
[26050,"'SLITRK5'",683,717,558,652.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex",null,"GO:0007268///chemical synaptic transmission+++GO:0051965///positive regulation of synapse assembly+++GO:0072358///cardiovascular system development+++GO:0009410///response to xenobiotic stimulus+++GO:0021756///striatum development+++GO:0007409///axonogenesis+++GO:0030534///adult behavior+++GO:0007625///grooming behavior+++GO:0043588///skin development+++GO:0048813///dendrite morphogenesis","SLIT and NTRK like family member 5","[SLIK5_HUMAN|Reviewed]RecName: Full=SLIT and NTRK-like protein 5; AltName: Full=Leucine-rich repeat-containing protein 11; Flags: Precursor;+++[Q4QQH1_HUMAN|Unreviewed]SubName: Full=SLIT and NTRK-like family, member 5 {ECO:0000313|EMBL:AAH98287.1};"]
[26071,"'RTL8A'",1617,1541,1470,1542.66666666667,{"$nulls":4},"GO:0005886///plasma membrane","GO:0005515///protein binding",null,"retrotransposon Gag like 8A","[RTL8A_HUMAN|Reviewed]RecName: Full=Retrotransposon Gag-like protein 8A {ECO:0000312|HGNC:HGNC:24514}; AltName: Full=Mammalian retrotransposon derived protein 8A;+++[Q6IPB9_HUMAN|Unreviewed]SubName: Full=FAM127B protein {ECO:0000313|EMBL:AAH71991.2}; Flags: Fragment;"]
[26112,"'CCDC69'",104,109,103.01,105.336666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0051233///spindle midzone+++GO:0015630///microtubule cytoskeleton+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0030496///midbody","GO:0008017///microtubule binding","GO:0051255///spindle midzone assembly","coiled-coil domain containing 69","[CCD69_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 69 {ECO:0000305};+++[D3DQH5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 69, isoform CRA_a {ECO:0000313|EMBL:EAW61683.1};+++[E5RK59_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 69 {ECO:0000313|Ensembl:ENSP00000430436};+++[H0YB32_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 69 {ECO:0000313|Ensembl:ENSP00000428588}; Flags: Fragment;+++[H0YBY5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 69 {ECO:0000313|Ensembl:ENSP00000430549}; Flags: Fragment;+++[Q7L2X4_HUMAN|Unreviewed]SubName: Full=CCDC69 protein {ECO:0000313|EMBL:AAH16647.2}; Flags: Fragment;"]
[26136,"'TES'",2331,1746.81,1846,1974.60333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0042127///regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation","testin LIM domain protein","[TES_HUMAN|Reviewed]RecName: Full=Testin; AltName: Full=TESS;+++[A4D0U5_HUMAN|Unreviewed]SubName: Full=Testis derived transcript (3 LIM domains) {ECO:0000313|EMBL:EAL24364.1}; SubName: Full=Testis derived transcript (3 LIM domains), isoform CRA_d {ECO:0000313|EMBL:EAW83497.1};+++[E0X098_HUMAN|Unreviewed]SubName: Full=Testin variant {ECO:0000313|EMBL:ACV74338.1}; Flags: Fragment;+++[F8W7T0_HUMAN|Unreviewed]SubName: Full=Testin {ECO:0000313|Ensembl:ENSP00000413002}; Flags: Fragment;+++[F8WDI4_HUMAN|Unreviewed]SubName: Full=Testin {ECO:0000313|Ensembl:ENSP00000420220};+++[H7BYK1_HUMAN|Unreviewed]SubName: Full=Testin {ECO:0000313|Ensembl:ENSP00000377124}; Flags: Fragment;"]
[26164,"'MTG2'",486.3,549.3,494.27,509.956666666667,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005761///mitochondrial ribosome+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane","GO:0046872///metal ion binding+++GO:0003924///GTPase activity+++GO:0000287///magnesium ion binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0042254///ribosome biogenesis+++GO:0070129///regulation of mitochondrial translation+++GO:0044065///regulation of respiratory system process+++GO:0006417///regulation of translation","mitochondrial ribosome associated GTPase 2","[MTG2_HUMAN|Reviewed]RecName: Full=Mitochondrial ribosome-associated GTPase 2; AltName: Full=GTP-binding protein 5; AltName: Full=Protein obg homolog 1; Short=ObgH1;+++[B4DRC1_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosome-associated GTPase 2 {ECO:0000313|Ensembl:ENSP00000435214}; SubName: Full=cDNA FLJ57421, highly similar to GTP-binding protein 5 {ECO:0000313|EMBL:BAG61233.1};+++[Q5JXJ0_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosome-associated GTPase 2 {ECO:0000313|Ensembl:ENSP00000414693}; Flags: Fragment;"]
[26225,"'ARL5A'",314,250,269,277.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network","GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0006886///intracellular protein transport+++GO:1903292///protein localization to Golgi membrane+++GO:0016192///vesicle-mediated transport","ADP ribosylation factor like GTPase 5A","[ARL5A_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 5A;+++[F8WER2_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 5A {ECO:0000313|Ensembl:ENSP00000393716};"]
[2624,"'GATA2'",653,745,656,684.666666666667,null,"H01481///Myelodysplastic syndrome (MDS)",null,null,"GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0003682///chromatin binding+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0070345///negative regulation of fat cell proliferation+++GO:0033993///response to lipid+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0001764///neuron migration+++GO:0006909///phagocytosis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045650///negative regulation of macrophage differentiation+++GO:0010629///negative regulation of gene expression+++GO:0001892///embryonic placenta development+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0048663///neuron fate commitment+++GO:0060872///semicircular canal development+++GO:0043306///positive regulation of mast cell degranulation+++GO:0006351///transcription, DNA-templated+++GO:0021983///pituitary gland development+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0007596///blood coagulation+++GO:0030154///cell differentiation+++GO:0021514///ventral spinal cord interneuron differentiation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0030182///neuron differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:2000977///regulation of forebrain neuron differentiation+++GO:0001709///cell fate determination+++GO:0010725///regulation of primitive erythrocyte differentiation+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:0045766///positive regulation of angiogenesis+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0001655///urogenital system development+++GO:0045666///positive regulation of neuron differentiation+++GO:0060216///definitive hemopoiesis+++GO:0097154///GABAergic neuron differentiation+++GO:0035019///somatic stem cell population maintenance+++GO:0090102///cochlea development+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0042472///inner ear morphogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0030097///hemopoiesis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010628///positive regulation of gene expression+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0035854///eosinophil fate commitment+++GO:0021533///cell differentiation in hindbrain+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0021954///central nervous system neuron development+++GO:0050766///positive regulation of phagocytosis+++GO:0048469///cell maturation+++GO:0035065///regulation of histone acetylation","GATA binding protein 2","[GATA2_HUMAN|Reviewed]RecName: Full=Endothelial transcription factor GATA-2; AltName: Full=GATA-binding protein 2;+++[A0A1D5RMQ8_HUMAN|Unreviewed]SubName: Full=Endothelial transcription factor GATA-2 {ECO:0000313|Ensembl:ENSP00000419532}; Flags: Fragment;+++[C9J965_HUMAN|Unreviewed]SubName: Full=Endothelial transcription factor GATA-2 {ECO:0000313|Ensembl:ENSP00000418132}; Flags: Fragment;"]
[26275,"'HIBCH'",136,127,124,129,"00640///Propanoate metabolism+++01100///Metabolic pathways+++01200///Carbon metabolism+++00280///Valine, leucine and isoleucine degradation+++00410///beta-Alanine metabolism","H01349///Methacrylic aciduria","M00013///Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA","R03158///3-Hydroxypropanoate + CoA <=> 3-Hydroxypropionyl-CoA + H2O+++R05064///(S)-3-Hydroxyisobutyryl-CoA hydrolase   (S)-3-Hydroxyisobutyryl-CoA + H2O <=> CoA + (S)-3-Hydroxyisobutyrate","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0016787///hydrolase activity+++GO:0003860///3-hydroxyisobutyryl-CoA hydrolase activity","GO:0006574///valine catabolic process+++GO:0009083///branched-chain amino acid catabolic process+++GO:0006635///fatty acid beta-oxidation","3-hydroxyisobutyryl-CoA hydrolase","[HIBCH_HUMAN|Reviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; EC=3.1.2.4; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase; Short=HIB-CoA hydrolase; Short=HIBYL-CoA-H; Flags: Precursor;+++[A0A140VJL0_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000256|RuleBase:RU363052}; EC=3.1.2.4 {ECO:0000256|RuleBase:RU363052}; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase {ECO:0000256|RuleBase:RU363052};+++[B8ZZZ0_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000256|RuleBase:RU363052}; EC=3.1.2.4 {ECO:0000256|RuleBase:RU363052}; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase {ECO:0000256|RuleBase:RU363052}; Flags: Fragment;+++[B9A058_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000256|RuleBase:RU363052}; EC=3.1.2.4 {ECO:0000256|RuleBase:RU363052}; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase {ECO:0000256|RuleBase:RU363052};+++[F8W8A6_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000256|RuleBase:RU363052}; EC=3.1.2.4 {ECO:0000256|RuleBase:RU363052}; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase {ECO:0000256|RuleBase:RU363052}; Flags: Fragment;+++[H7BYI7_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000256|RuleBase:RU363052}; EC=3.1.2.4 {ECO:0000256|RuleBase:RU363052}; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase {ECO:0000256|RuleBase:RU363052}; Flags: Fragment;+++[H7C126_HUMAN|Unreviewed]SubName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000398060}; Flags: Fragment;+++[H7C1A5_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000256|RuleBase:RU363052}; EC=3.1.2.4 {ECO:0000256|RuleBase:RU363052}; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase {ECO:0000256|RuleBase:RU363052}; Flags: Fragment;+++[H7C400_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyryl-CoA hydrolase, mitochondrial {ECO:0000256|RuleBase:RU363052}; EC=3.1.2.4 {ECO:0000256|RuleBase:RU363052}; AltName: Full=3-hydroxyisobutyryl-coenzyme A hydrolase {ECO:0000256|RuleBase:RU363052}; Flags: Fragment;"]
[2629,"'GBA'",5236,4951,4491,4892.66666666667,"00600///Sphingolipid metabolism+++04142///Lysosome+++01100///Metabolic pathways+++00511///Other glycan degradation","H00426///Defects in the degradation of ganglioside+++H00126///Gaucher disease+++H00066///Lewy body dementia (LBD)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,"R01498///D-Glucosyl-N-acylsphingosine glucohydrolase   beta-D-Glucosyl-(1<->1)-ceramide + H2O <=> D-Glucose + N-Acylsphingosine","GO:0005764///lysosome+++GO:0043202///lysosomal lumen+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0005765///lysosomal membrane+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome","GO:0005102///signaling receptor binding+++GO:0005124///scavenger receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004348///glucosylceramidase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds","GO:0032269///negative regulation of cellular protein metabolic process+++GO:1903061///positive regulation of protein lipidation+++GO:0009268///response to pH+++GO:1904457///positive regulation of neuronal action potential+++GO:0007005///mitochondrion organization+++GO:0051246///regulation of protein metabolic process+++GO:1905165///regulation of lysosomal protein catabolic process+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043627///response to estrogen+++GO:0006629///lipid metabolic process+++GO:0033574///response to testosterone+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043243///positive regulation of protein complex disassembly+++GO:0050728///negative regulation of inflammatory response+++GO:1905037///autophagosome organization+++GO:0033561///regulation of water loss via skin+++GO:0043407///negative regulation of MAP kinase activity+++GO:0051247///positive regulation of protein metabolic process+++GO:0032268///regulation of cellular protein metabolic process+++GO:1901805///beta-glucoside catabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006680///glucosylceramide catabolic process+++GO:0032715///negative regulation of interleukin-6 production+++GO:0008152///metabolic process+++GO:0031175///neuron projection development+++GO:0043589///skin morphogenesis+++GO:0036473///cell death in response to oxidative stress+++GO:0023021///termination of signal transduction+++GO:0009267///cellular response to starvation+++GO:0032463///negative regulation of protein homooligomerization+++GO:0071548///response to dexamethasone+++GO:0097066///response to thyroid hormone+++GO:0071356///cellular response to tumor necrosis factor+++GO:1901215///negative regulation of neuron death+++GO:0046513///ceramide biosynthetic process+++GO:0016241///regulation of macroautophagy+++GO:0046512///sphingosine biosynthetic process+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization","glucosylceramidase beta","[GLCM_HUMAN|Reviewed]RecName: Full=Glucosylceramidase; EC=3.2.1.45; AltName: Full=Acid beta-glucosidase; AltName: Full=Alglucerase; AltName: Full=Beta-glucocerebrosidase; Short=Beta-GC; AltName: Full=D-glucosyl-N-acylsphingosine glucohydrolase; AltName: Full=Imiglucerase; Flags: Precursor;+++[A0A068F658_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[A0A0G2JLB3_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[A0A0G2JNZ0_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[A0A0G2JNZ5_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[B7Z6S9_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[D3DV87_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};"]
[2644,"'GCHFR'",61,61,58,60,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0042470///melanosome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0016020///membrane+++GO:0030425///dendrite","GO:0016597///amino acid binding+++GO:0030742///GTP-dependent protein binding+++GO:0016787///hydrolase activity+++GO:0044549///GTP cyclohydrolase binding+++GO:0019899///enzyme binding+++GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0051291///protein heterooligomerization+++GO:0051186///cofactor metabolic process+++GO:0043105///negative regulation of GTP cyclohydrolase I activity+++GO:0006809///nitric oxide biosynthetic process+++GO:0042133///neurotransmitter metabolic process+++GO:0009890///negative regulation of biosynthetic process","GTP cyclohydrolase I feedback regulator","[GFRP_HUMAN|Reviewed]RecName: Full=GTP cyclohydrolase 1 feedback regulatory protein; Short=GFRP; AltName: Full=GTP cyclohydrolase I feedback regulatory protein; AltName: Full=p35;+++[A0A087WTI4_HUMAN|Unreviewed]SubName: Full=GTP cyclohydrolase 1 feedback regulatory protein {ECO:0000313|Ensembl:ENSP00000477896};+++[H0YNM1_HUMAN|Unreviewed]SubName: Full=GTP cyclohydrolase 1 feedback regulatory protein {ECO:0000313|Ensembl:ENSP00000454067};+++[H0YNX7_HUMAN|Unreviewed]SubName: Full=GTP cyclohydrolase 1 feedback regulatory protein {ECO:0000313|Ensembl:ENSP00000454195}; SubName: Full=GTP cyclohydrolase I feedback regulator, isoform CRA_a {ECO:0000313|EMBL:EAW92442.1};+++[L0R6H1_HUMAN|Unreviewed]SubName: Full=Alternative protein GCHFR {ECO:0000313|EMBL:CCO13735.1};"]
[2648,"'KAT2A'",806,946,1020,924,"05203///Viral carcinogenesis+++04330///Notch signaling pathway+++05166///HTLV-I infection+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0072686///mitotic spindle+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0033276///transcription factor TFTC complex+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005694///chromosome+++GO:0000790///nuclear chromatin+++GO:0030914///STAGA complex+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0005654///nucleoplasm+++GO:0000123///histone acetyltransferase complex+++GO:0045252///oxoglutarate dehydrogenase complex+++GO:0005634///nucleus","GO:0043997///histone acetyltransferase activity (H4-K12 specific)+++GO:0016407///acetyltransferase activity+++GO:0106078///histone succinyltransferase activity+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0008080///N-acetyltransferase activity+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0003682///chromatin binding+++GO:0019903///protein phosphatase binding+++GO:0005515///protein binding+++GO:0061733///peptide-lysine-N-acetyltransferase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0042826///histone deacetylase binding+++GO:0010484///H3 histone acetyltransferase activity","GO:0016573///histone acetylation+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0031346///positive regulation of cell projection organization+++GO:0022037///metencephalon development+++GO:0008283///cell proliferation+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:0035948///positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007507///heart development+++GO:0043983///histone H4-K12 acetylation+++GO:0035066///positive regulation of histone acetylation+++GO:0001756///somitogenesis+++GO:0031667///response to nutrient levels+++GO:0016578///histone deubiquitination+++GO:0106077///histone succinylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0044154///histone H3-K14 acetylation+++GO:0048312///intracellular distribution of mitochondria+++GO:0043966///histone H3 acetylation+++GO:0048167///regulation of synaptic plasticity+++GO:0071929///alpha-tubulin acetylation+++GO:0001701///in utero embryonic development+++GO:0046600///negative regulation of centriole replication+++GO:0035264///multicellular organism growth+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0016579///protein deubiquitination+++GO:0016032///viral process+++GO:0021537///telencephalon development+++GO:0007616///long-term memory+++GO:0007399///nervous system development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060173///limb development+++GO:0014070///response to organic cyclic compound+++GO:0030901///midbrain development+++GO:0001843///neural tube closure+++GO:0050863///regulation of T cell activation+++GO:0018393///internal peptidyl-lysine acetylation+++GO:0006338///chromatin remodeling+++GO:0031647///regulation of protein stability+++GO:0001816///cytokine production","lysine acetyltransferase 2A","[KAT2A_HUMAN|Reviewed]RecName: Full=Histone acetyltransferase KAT2A; EC=2.3.1.48 {ECO:0000269|PubMed:29211711}; AltName: Full=General control of amino acid synthesis protein 5-like 2 {ECO:0000250|UniProtKB:Q9JHD2}; AltName: Full=Histone acetyltransferase GCN5 {ECO:0000303|PubMed:8552087, ECO:0000303|PubMed:9611240}; Short=hGCN5 {ECO:0000303|PubMed:8552087, ECO:0000303|PubMed:9611240}; AltName: Full=Histone succinyltransferase KAT2A {ECO:0000305}; EC=2.3.1.- {ECO:0000269|PubMed:29211711}; AltName: Full=Lysine acetyltransferase 2A {ECO:0000305}; AltName: Full=STAF97 {ECO:0000303|PubMed:11564863};+++[K7EPC4_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT2A {ECO:0000313|Ensembl:ENSP00000467324}; Flags: Fragment;+++[K7ERS6_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT2A {ECO:0000313|Ensembl:ENSP00000468390}; Flags: Fragment;"]
[26548,"'ITGB1BP2'",3,9,2,4.66666666666667,{"$nulls":4},"GO:0030018///Z disc","GO:0008270///zinc ion binding+++GO:0005509///calcium ion binding+++GO:0005178///integrin binding+++GO:0017124///SH3 domain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0007517///muscle organ development+++GO:0007165///signal transduction","integrin subunit beta 1 binding protein 2","[ITBP2_HUMAN|Reviewed]RecName: Full=Integrin beta-1-binding protein 2; AltName: Full=Melusin;"]
[26586,"'CKAP2'",671,537,559,589,null,"H01857///Filippi syndrome",null,null,"GO:0005856///cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0005813///centrosome+++GO:0000922///spindle pole+++GO:0015630///microtubule cytoskeleton+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005819///spindle",null,"GO:0006915///apoptotic process+++GO:0007049///cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000281///mitotic cytokinesis+++GO:0007026///negative regulation of microtubule depolymerization","cytoskeleton associated protein 2","[CKAP2_HUMAN|Reviewed]RecName: Full=Cytoskeleton-associated protein 2; AltName: Full=CTCL tumor antigen se20-10; AltName: Full=Tumor- and microtubule-associated protein;+++[B2RMQ4_HUMAN|Unreviewed]SubName: Full=Cytoskeleton associated protein 2 {ECO:0000313|EMBL:AAI36333.1}; SubName: Full=Cytoskeleton associated protein 2, isoform CRA_b {ECO:0000313|EMBL:EAW55890.1};+++[C9J649_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 2 {ECO:0000313|Ensembl:ENSP00000418431}; Flags: Fragment;+++[C9J7Y4_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 2 {ECO:0000313|Ensembl:ENSP00000418224}; Flags: Fragment;"]
[267020,"'ATP5MGL'",1,0,2,1,{"$nulls":4},"GO:0016020///membrane+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0031966///mitochondrial membrane+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion","GO:0015078///proton transmembrane transporter activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism","GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport","ATP synthase membrane subunit g like","[AT5L2_HUMAN|Reviewed]RecName: Full=Putative ATP synthase subunit g 2, mitochondrial {ECO:0000305}; Short=ATPase subunit g 2; AltName: Full=ATP synthase membrane subunit g-like protein {ECO:0000305};"]
[2687,"'GGT5'",55,69,67,63.6666666666667,"00590///Arachidonic acid metabolism+++00460///Cyanoamino acid metabolism+++00430///Taurine and hypotaurine metabolism+++00480///Glutathione metabolism+++01100///Metabolic pathways",null,null,"R03971///gamma-glutamyl-beta-aminopropiononitrile amidohydrolase   3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O+++R00494///glutathione gamma-glutamylaminopeptidase   Glutathione + H2O <=> Cys-Gly + L-Glutamate+++R01687///(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase   (5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine+++R01262///glutathione:L-amino-acid 5-glutamyltransferase   Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid+++R03970///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase   3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O+++R03916///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase   R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate+++R09875///leukotriene-C4 hydrolase   Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate","GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0016021///integral component of membrane","GO:0103068///leukotriene C4 gamma-glutamyl transferase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0002951///leukotriene-C(4) hydrolase+++GO:0016740///transferase activity+++GO:0102953///hypoglycin A gamma-glutamyl transpeptidase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0036374///glutathione hydrolase activity+++GO:0000048///peptidyltransferase activity","GO:0019370///leukotriene biosynthetic process+++GO:0006691///leukotriene metabolic process+++GO:0006954///inflammatory response+++GO:0006749///glutathione metabolic process+++GO:0006412///translation+++GO:0006751///glutathione catabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006508///proteolysis+++GO:1901750///leukotriene D4 biosynthetic process+++GO:0019344///cysteine biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0006536///glutamate metabolic process","gamma-glutamyltransferase 5","[GGT5_HUMAN|Reviewed]RecName: Full=Glutathione hydrolase 5 proenzyme; EC=3.4.19.13; AltName: Full=Gamma-glutamyl transpeptidase-related enzyme; Short=GGT-rel; AltName: Full=Gamma-glutamyltransferase 5; Short=GGT 5; EC=2.3.2.2; AltName: Full=Gamma-glutamyltransferase-like activity 1; AltName: Full=Gamma-glutamyltranspeptidase 5; AltName: Full=Leukotriene-C4 hydrolase; EC=3.4.19.14; Contains: RecName: Full=Glutathione hydrolase 5 heavy chain; Contains: RecName: Full=Glutathione hydrolase 5 light chain; Flags: Precursor;+++[B4DEL3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50454, moderately similar to Gamma-glutamyltransferase 5 (EC2.3.2.2) {ECO:0000313|EMBL:BAG57124.1};+++[C9JU68_HUMAN|Unreviewed]SubName: Full=Glutathione hydrolase 5 proenzyme {ECO:0000313|Ensembl:ENSP00000412964}; Flags: Fragment;+++[H7C1X2_HUMAN|Unreviewed]SubName: Full=Glutathione hydrolase 5 proenzyme {ECO:0000313|Ensembl:ENSP00000402917}; Flags: Fragment;"]
[2697,"'GJA1'",7090,6419,6044,6517.66666666667,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04540///Gap junction","H00449///Oculodentodigital dysplasia+++H00605///Deafness, autosomal recessive+++H00710///Erythrokeratodermia variabilis+++H01272///Hypoplastic left heart syndrome (HLHS)+++H00547///Atrioventricular septal defect+++H01095///Syndactyly",null,null,"GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0005921///gap junction+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0005922///connexin complex+++GO:0005783///endoplasmic reticulum+++GO:0030660///Golgi-associated vesicle membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0000139///Golgi membrane","GO:0022857///transmembrane transporter activity+++GO:0015075///ion transmembrane transporter activity+++GO:0055077///gap junction hemi-channel activity+++GO:0043014///alpha-tubulin binding+++GO:1903763///gap junction channel activity involved in cell communication by electrical coupling+++GO:0005243///gap junction channel activity+++GO:0086075///gap junction channel activity involved in cardiac conduction electrical coupling+++GO:0005515///protein binding","GO:0007267///cell-cell signaling+++GO:0099111///microtubule-based transport+++GO:0030308///negative regulation of cell growth+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0007165///signal transduction+++GO:0016264///gap junction assembly+++GO:0034220///ion transmembrane transport+++GO:0007507///heart development+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0007154///cell communication+++GO:0006936///muscle contraction+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0010644///cell communication by electrical coupling","gap junction protein alpha 1","[CXA1_HUMAN|Reviewed]RecName: Full=Gap junction alpha-1 protein; AltName: Full=Connexin-43; Short=Cx43; AltName: Full=Gap junction 43 kDa heart protein;"]
[27013,"'CNPPD1'",1115,1057,807,993,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0019901///protein kinase binding","GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity","cyclin Pas1/PHO80 domain containing 1","[CNPD1_HUMAN|Reviewed]RecName: Full=Protein CNPPD1; AltName: Full=Cyclin Pas1/PHO80 domain-containing protein 1;+++[A0A024R432_HUMAN|Unreviewed]SubName: Full=Chromosome 2 open reading frame 24, isoform CRA_b {ECO:0000313|EMBL:EAW70687.1};+++[C9J597_HUMAN|Unreviewed]SubName: Full=Protein CNPPD1 {ECO:0000313|Ensembl:ENSP00000405997}; Flags: Fragment;+++[C9JF31_HUMAN|Unreviewed]SubName: Full=Protein CNPPD1 {ECO:0000313|Ensembl:ENSP00000410109}; Flags: Fragment;"]
[27044,"'SND1'",5267,5528,5208,5334.33333333333,"05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis",{"$nulls":3},"GO:0005829///cytosol+++GO:0097433///dense body+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016442///RISC complex+++GO:0042470///melanosome+++GO:0005634///nucleus","GO:0004521///endoribonuclease activity+++GO:1905172///RISC complex binding+++GO:0004519///endonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0003712///transcription coregulator activity+++GO:0016787///hydrolase activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0010587///miRNA catabolic process+++GO:0031047///gene silencing by RNA+++GO:1903506///regulation of nucleic acid-templated transcription+++GO:0010564///regulation of cell cycle process+++GO:0006401///RNA catabolic process+++GO:0016032///viral process+++GO:0001649///osteoblast differentiation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","staphylococcal nuclease and tudor domain containing 1","[SND1_HUMAN|Reviewed]RecName: Full=Staphylococcal nuclease domain-containing protein 1; EC=3.1.31.1 {ECO:0000269|PubMed:18453631, ECO:0000269|PubMed:28546213}; AltName: Full=100 kDa coactivator; AltName: Full=EBNA2 coactivator p100; AltName: Full=Tudor domain-containing protein 11; AltName: Full=p100 co-activator;+++[A0A140VK49_HUMAN|Unreviewed]SubName: Full=Staphylococcal nuclease domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW83636.1}; SubName: Full=Testis tissue sperm-binding protein Li 82P {ECO:0000313|EMBL:AEE61186.1};+++[H7C597_HUMAN|Unreviewed]SubName: Full=Staphylococcal nuclease domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000419327}; Flags: Fragment;"]
[27089,"'UQCRQ'",685,522,662,623,"05012///Parkinson's disease+++05016///Huntington's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04714///Thermogenesis+++01100///Metabolic pathways+++04260///Cardiac muscle contraction+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease","H02086///Mitochondrial complex III deficiency","M00152///Cytochrome bc1 complex",null,"GO:0005750///mitochondrial respiratory chain complex III+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0070469///respiratory chain","GO:0008121///ubiquinol-cytochrome-c reductase activity","GO:0021680///cerebellar Purkinje cell layer development+++GO:0021548///pons development+++GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0021860///pyramidal neuron development+++GO:0055114///oxidation-reduction process+++GO:0021539///subthalamus development+++GO:0021854///hypothalamus development+++GO:0030901///midbrain development+++GO:0021766///hippocampus development+++GO:0021794///thalamus development","ubiquinol-cytochrome c reductase complex III subunit VII","[QCR8_HUMAN|Reviewed]RecName: Full=Cytochrome b-c1 complex subunit 8; AltName: Full=Complex III subunit 8; AltName: Full=Complex III subunit VIII; AltName: Full=Ubiquinol-cytochrome c reductase complex 9.5 kDa protein; AltName: Full=Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C;"]
[27112,"'FAM155B'",12,17,9,12.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0015275///stretch-activated, cation-selective, calcium channel activity","GO:0098703///calcium ion import across plasma membrane","family with sequence similarity 155 member B","[F155B_HUMAN|Reviewed]RecName: Full=Transmembrane protein FAM155B; AltName: Full=Protein TED; AltName: Full=Transmembrane protein 28;"]
[27141,"'CIDEB'",83,91,78,84,"04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005829///cytosol+++GO:0005811///lipid droplet+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0010942///positive regulation of cell death+++GO:0006915///apoptotic process+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0097194///execution phase of apoptosis+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage","cell death-inducing DFFA-like effector b","[CIDEB_HUMAN|Reviewed]RecName: Full=Cell death activator CIDE-B; AltName: Full=Cell death-inducing DFFA-like effector B;+++[G3V4E2_HUMAN|Unreviewed]SubName: Full=Cell death activator CIDE-B {ECO:0000313|Ensembl:ENSP00000451744}; Flags: Fragment;"]
[2717,"'GLA'",208,151,144,167.666666666667,"00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++01100///Metabolic pathways+++00561///Glycerolipid metabolism+++00600///Sphingolipid metabolism+++00052///Galactose metabolism+++04142///Lysosome","H00125///Fabry disease",null,"R01104///Galactosylglycerol galactohydrolase   3-beta-D-Galactosyl-sn-glycerol + H2O <=> D-Galactose + Glycerol+++R01194///3-O-alpha-D-Galactosyl-1D-myo-inositol galactohydrolase; 1-alpha-D-Galactosyl-myo-inositol   alpha-D-Galactosyl-(1->3)-1D-myo-inositol + H2O <=> myo-Inositol + D-Galactose+++R06091///Melibiose + H2O <=> D-Galactose + D-Glucose+++R04019///Digalactosylceramide galactohydrolase   Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose+++R05549///D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose+++R01103///Raffinose galactohydrolase   Raffinose + H2O <=> D-Galactose + Sucrose+++R02926///Melibiitol galactohydrolase   Melibiitol + H2O <=> D-Sorbitol + D-Galactose+++R05961///H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide+++R04470///Digalactosyl-diacylglycerol galactohydrolase   Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose+++R01329///Epimelibiose galactohydrolase   Epimelibiose + H2O <=> D-Mannose + D-Galactose+++R03634///Stachyose + H2O <=> Raffinose + D-Galactose+++R01101///melibiose galactohydrolase   Melibiose + H2O <=> D-Galactose + D-Glucose","GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0035578///azurophil granule lumen+++GO:0005794///Golgi apparatus+++GO:0005764///lysosome+++GO:0043202///lysosomal lumen","GO:0016936///galactoside binding+++GO:0005102///signaling receptor binding+++GO:0042803///protein homodimerization activity+++GO:0004557///alpha-galactosidase activity+++GO:0052692///raffinose alpha-galactosidase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity","GO:0006687///glycosphingolipid metabolic process+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0043312///neutrophil degranulation+++GO:0009311///oligosaccharide metabolic process+++GO:0016139///glycoside catabolic process+++GO:0046479///glycosphingolipid catabolic process+++GO:0046477///glycosylceramide catabolic process","galactosidase alpha","[AGAL_HUMAN|Reviewed]RecName: Full=Alpha-galactosidase A; EC=3.2.1.22 {ECO:0000269|PubMed:26415523, ECO:0000269|PubMed:27211852}; AltName: Full=Alpha-D-galactosidase A; AltName: Full=Alpha-D-galactoside galactohydrolase; AltName: Full=Melibiase; AltName: INN=Agalsidase; Flags: Precursor;+++[Q53Y83_HUMAN|Unreviewed]RecName: Full=Alpha-galactosidase {ECO:0000256|RuleBase:RU361168}; EC=3.2.1.- {ECO:0000256|RuleBase:RU361168};"]
[27230,"'SERP1'",710,627,651,662.666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005840///ribosome+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005881///cytoplasmic microtubule+++GO:0016020///membrane","GO:0005515///protein binding","GO:0009791///post-embryonic development+++GO:0007009///plasma membrane organization+++GO:0046622///positive regulation of organ growth+++GO:0010259///multicellular organism aging+++GO:0015031///protein transport+++GO:0060124///positive regulation of growth hormone secretion+++GO:0032024///positive regulation of insulin secretion+++GO:0006006///glucose metabolic process+++GO:0006464///cellular protein modification process+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0045727///positive regulation of translation+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0001501///skeletal system development+++GO:0048644///muscle organ morphogenesis+++GO:0006486///protein glycosylation","stress associated endoplasmic reticulum protein 1","[SERP1_HUMAN|Reviewed]RecName: Full=Stress-associated endoplasmic reticulum protein 1; AltName: Full=Ribosome-attached membrane protein 4;+++[C9JSB0_HUMAN|Unreviewed]RecName: Full=Stress-associated endoplasmic reticulum protein {ECO:0000256|RuleBase:RU364120};+++[C9JUH5_HUMAN|Unreviewed]RecName: Full=Stress-associated endoplasmic reticulum protein {ECO:0000256|RuleBase:RU364120};"]
[27248,"'ERLEC1'",956,961,825,914,"04141///Protein processing in endoplasmic reticulum",null,"M00403///HRD1/SEL1 ERAD complex",null,"GO:0044322///endoplasmic reticulum quality control compartment+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0051082///unfolded protein binding+++GO:0005515///protein binding","GO:0030433///ubiquitin-dependent ERAD pathway+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol+++GO:0036503///ERAD pathway+++GO:0055085///transmembrane transport+++GO:0030970///retrograde protein transport, ER to cytosol","endoplasmic reticulum lectin 1","[ERLEC_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum lectin 1; AltName: Full=ER lectin; Short=Erlectin; AltName: Full=XTP3-transactivated gene B protein; Flags: Precursor;+++[V9HWD3_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 117 {ECO:0000313|EMBL:ACJ13730.1};"]
[2729,"'GCLC'",357,396,379,377.333333333333,"00480///Glutathione metabolism+++00270///Cysteine and methionine metabolism+++04216///Ferroptosis+++04212///Longevity regulating pathway - worm+++01100///Metabolic pathways","H00668///Anemia due to disorders of glutathione metabolism","M00118///Glutathione biosynthesis, glutamate => glutathione","R00894///L-glutamate:L-cysteine gamma-ligase (ADP-forming)   ATP + L-Glutamate + L-Cysteine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteine+++R10993///L-glutamate:2-aminobutanoate gamma-ligase (ADP-forming)   ATP + L-Glutamate + (S)-2-Aminobutanoate <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-2-aminobutyrate","GO:0005829///cytosol+++GO:0017109///glutamate-cysteine ligase complex","GO:0016595///glutamate binding+++GO:0050662///coenzyme binding+++GO:0003824///catalytic activity+++GO:0000287///magnesium ion binding+++GO:0004357///glutamate-cysteine ligase activity+++GO:0000166///nucleotide binding+++GO:0043531///ADP binding+++GO:0046982///protein heterodimerization activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity","GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0046685///response to arsenic-containing substance+++GO:0007568///aging+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0051409///response to nitrosative stress+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0032869///cellular response to insulin stimulus+++GO:0070555///response to interleukin-1+++GO:0031397///negative regulation of protein ubiquitination+++GO:0046686///response to cadmium ion+++GO:0045454///cell redox homeostasis+++GO:0007584///response to nutrient+++GO:0071333///cellular response to glucose stimulus+++GO:2000490///negative regulation of hepatic stellate cell activation+++GO:0009408///response to heat+++GO:0044752///response to human chorionic gonadotropin+++GO:0006534///cysteine metabolic process+++GO:0051900///regulation of mitochondrial depolarization+++GO:0097069///cellular response to thyroxine stimulus+++GO:0008637///apoptotic mitochondrial changes+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0014823///response to activity+++GO:0009725///response to hormone+++GO:0009410///response to xenobiotic stimulus+++GO:0006979///response to oxidative stress+++GO:0006749///glutathione metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0019852///L-ascorbic acid metabolic process+++GO:0050880///regulation of blood vessel size+++GO:0006750///glutathione biosynthetic process+++GO:0043066///negative regulation of apoptotic process+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0071260///cellular response to mechanical stimulus+++GO:0006536///glutamate metabolic process","glutamate-cysteine ligase catalytic subunit","[GSH1_HUMAN|Reviewed]RecName: Full=Glutamate--cysteine ligase catalytic subunit; EC=6.3.2.2; AltName: Full=GCS heavy chain; AltName: Full=Gamma-ECS; AltName: Full=Gamma-glutamylcysteine synthetase;+++[A0A0C4DGB2_HUMAN|Unreviewed]SubName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000313|Ensembl:ENSP00000421908};+++[A0A2R8Y648_HUMAN|Unreviewed]SubName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000313|Ensembl:ENSP00000495056};+++[A0A2R8YEL6_HUMAN|Unreviewed]SubName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000313|Ensembl:ENSP00000495686}; Flags: Fragment;+++[B4E2I4_HUMAN|Unreviewed]SubName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000313|Ensembl:ENSP00000482756}; SubName: Full=cDNA FLJ58227, highly similar to Glutamate--cysteine ligase catalytic subunit {ECO:0000313|EMBL:BAG65146.1};+++[D6RGF8_HUMAN|Unreviewed]SubName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000313|Ensembl:ENSP00000421228};+++[D6RIT4_HUMAN|Unreviewed]SubName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000313|Ensembl:ENSP00000427403}; Flags: Fragment;+++[E1CEI4_HUMAN|Unreviewed]SubName: Full=Glutamate--cysteine ligase catalytic subunit {ECO:0000313|Ensembl:ENSP00000424211}; SubName: Full=Glutamate-cysteine ligase delta4 alternative splicing variant {ECO:0000313|EMBL:BAJ21361.1};+++[Q14TF0_HUMAN|Unreviewed]SubName: Full=Glutamate-cysteine ligase {ECO:0000313|EMBL:BAE97618.1}; SubName: Full=Glutamate-cysteine ligase, catalytic subunit, isoform CRA_a {ECO:0000313|EMBL:EAX04425.1}; SubName: Full=cDNA, FLJ94028, Homo sapiens glutamate-cysteine ligase, catalytic subunit (GCLC),mRNA {ECO:0000313|EMBL:BAG36264.1};"]
[27292,"'DIMT1'",217,185,212,204.666666666667,null,"H01881///Complex cortical dysplasia with other brain malformations",null,"R10716///S-adenosyl-L-methionine:rRNA (adenine-N6-)-dimethyltransferase   2 S-Adenosyl-L-methionine + Adenine in rRNA <=> 2 S-Adenosyl-L-homocysteine + N6-Dimethyladenine in rRNA","GO:0005654///nucleoplasm+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005730///nucleolus","GO:0052909///18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008649///rRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0000179///rRNA (adenine-N6,N6-)-dimethyltransferase activity","GO:0032259///methylation+++GO:0031167///rRNA methylation+++GO:0006364///rRNA processing+++GO:0000154///rRNA modification+++GO:2000234///positive regulation of rRNA processing","DIM1 dimethyladenosine transferase 1 homolog","[DIM1_HUMAN|Reviewed]RecName: Full=Probable dimethyladenosine transferase; EC=2.1.1.183 {ECO:0000269|PubMed:25851604}; AltName: Full=DIM1 dimethyladenosine transferase 1 homolog; AltName: Full=DIM1 dimethyladenosine transferase 1-like; AltName: Full=Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; AltName: Full=Probable 18S rRNA dimethylase; AltName: Full=Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase;+++[A0A0C4DGB1_HUMAN|Unreviewed]RecName: Full=rRNA adenine N(6)-methyltransferase {ECO:0000256|RuleBase:RU362106}; EC=2.1.1.- {ECO:0000256|RuleBase:RU362106};+++[A8K9K8_HUMAN|Unreviewed]RecName: Full=rRNA adenine N(6)-methyltransferase {ECO:0000256|RuleBase:RU362106}; EC=2.1.1.- {ECO:0000256|RuleBase:RU362106};+++[D6RCL3_HUMAN|Unreviewed]RecName: Full=rRNA adenine N(6)-methyltransferase {ECO:0000256|RuleBase:RU362106}; EC=2.1.1.- {ECO:0000256|RuleBase:RU362106};"]
[27315,"'PGAP2'",510,614,555,559.666666666667,"05100///Bacterial invasion of epithelial cells+++04137///Mitophagy - animal+++05132///Salmonella infection+++05131///Shigellosis+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008565///protein transporter activity","GO:0006506///GPI anchor biosynthetic process+++GO:0015031///protein transport","post-GPI attachment to proteins 2","[PGAP2_HUMAN|Reviewed]RecName: Full=Post-GPI attachment to proteins factor 2; AltName: Full=FGF receptor-activating protein 1;+++[A0A024RCC6_HUMAN|Unreviewed]SubName: Full=FGF receptor activating protein 1, isoform CRA_d {ECO:0000313|EMBL:EAX02573.1};+++[A0A024RCD5_HUMAN|Unreviewed]SubName: Full=FGF receptor activating protein 1, isoform CRA_a {ECO:0000313|EMBL:EAX02572.1}; SubName: Full=Post-GPI attachment to proteins 2 isoform 4 {ECO:0000313|EMBL:ALQ34069.1};+++[A0A0A0MS75_HUMAN|Unreviewed]SubName: Full=FGF receptor activating protein 1, isoform CRA_e {ECO:0000313|EMBL:EAX02574.1}; SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000380188};+++[A0A0S2Z568_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins 2 isoform 1 {ECO:0000313|EMBL:ALQ34066.1}; Flags: Fragment;+++[A8MYS5_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000380183};+++[A8MZF5_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000380190};+++[B7Z2X5_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000434401}; SubName: Full=cDNA FLJ54959 {ECO:0000313|EMBL:BAH12011.1};+++[E9PKT0_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000435338};+++[E9PQ19_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000434507}; Flags: Fragment;+++[E9PRZ2_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins 2 isoform 2 {ECO:0000313|EMBL:ALQ34067.1}; SubName: Full=Post-GPI attachment to proteins 2 isoform 3 {ECO:0000313|EMBL:ALQ34068.1}; SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000432215};+++[H0YCQ4_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000432123};+++[H0YDC6_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000433377};+++[H0YDJ5_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000433748};+++[H0YDQ4_HUMAN|Unreviewed]SubName: Full=FGF receptor activating protein 1, isoform CRA_c {ECO:0000313|EMBL:EAX02570.1}; SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000434088};+++[H0YEE9_HUMAN|Unreviewed]SubName: Full=Post-GPI attachment to proteins factor 2 {ECO:0000313|Ensembl:ENSP00000435703};"]
[27343,"'POLL'",672,766,712,716.666666666667,"03410///Base excision repair+++03450///Non-homologous end-joining",null,"M00296///BER complex",null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0034061///DNA polymerase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0046872///metal ion binding+++GO:0003887///DNA-directed DNA polymerase activity","GO:0000724///double-strand break repair via homologous recombination+++GO:0006289///nucleotide-excision repair+++GO:0006260///DNA replication+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:0006287///base-excision repair, gap-filling+++GO:0071897///DNA biosynthetic process+++GO:0016446///somatic hypermutation of immunoglobulin genes","DNA polymerase lambda","[DPOLL_HUMAN|Reviewed]RecName: Full=DNA polymerase lambda {ECO:0000305}; Short=Pol Lambda {ECO:0000305}; EC=2.7.7.7 {ECO:0000269|PubMed:10887191, ECO:0000269|PubMed:10982892, ECO:0000269|PubMed:12809503, ECO:0000269|PubMed:14627824, ECO:0000269|PubMed:15537631, ECO:0000269|PubMed:19806195}; EC=4.2.99.- {ECO:0000269|PubMed:11457865, ECO:0000269|PubMed:19806195}; AltName: Full=DNA polymerase beta-2 {ECO:0000303|PubMed:10887191}; Short=Pol beta2 {ECO:0000303|PubMed:10887191}; AltName: Full=DNA polymerase kappa {ECO:0000303|Ref.1};+++[A8K860_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77175, highly similar to Homo sapiens DNA polymerase lamda2 mRNA {ECO:0000313|EMBL:BAF84914.1};+++[B4DE17_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53301, highly similar to DNA polymerase lambda {ECO:0000313|EMBL:BAG56928.1};+++[Q5JQN9_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000411678}; Flags: Fragment;+++[Q5JQP0_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000414293}; Flags: Fragment;+++[Q5JQP1_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000400517}; Flags: Fragment;+++[Q5JQP2_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000400676}; Flags: Fragment;+++[Q5JQP3_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000406791}; Flags: Fragment;+++[Q5JQP4_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000343102};+++[Q5JQP7_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000390093}; Flags: Fragment;+++[Q5JQP8_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000359191}; SubName: Full=Polymerase (DNA directed), lambda, isoform CRA_e {ECO:0000313|EMBL:EAW49761.1};+++[Q5ZEY5_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|EMBL:CAH59754.1}; EC=2.7.7.7 {ECO:0000313|EMBL:CAH59754.1}; Flags: Fragment;+++[Q5ZEY6_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|EMBL:CAH59753.1}; EC=2.7.7.7 {ECO:0000313|EMBL:CAH59753.1}; Flags: Fragment;+++[Q9HBN3_HUMAN|Unreviewed]SubName: Full=DNA polymerase lambda {ECO:0000313|Ensembl:ENSP00000359187}; SubName: Full=Polymerase (DNA directed), lambda, isoform CRA_i {ECO:0000313|EMBL:EAW49765.1};"]
[2739,"'GLO1'",1242,993,1092,1109,"00620///Pyruvate metabolism",null,null,"R02530///(R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)   (R)-S-Lactoylglutathione <=> Glutathione + Methylglyoxal","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0004462///lactoylglutathione lyase activity+++GO:0016829///lyase activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0006749///glutathione metabolic process+++GO:0030316///osteoclast differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0009438///methylglyoxal metabolic process+++GO:0006090///pyruvate metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II","glyoxalase I","[LGUL_HUMAN|Reviewed]RecName: Full=Lactoylglutathione lyase; EC=4.4.1.5; AltName: Full=Aldoketomutase; AltName: Full=Glyoxalase I; Short=Glx I; AltName: Full=Ketone-aldehyde mutase; AltName: Full=Methylglyoxalase; AltName: Full=S-D-lactoylglutathione methylglyoxal lyase;+++[V9HW62_HUMAN|Unreviewed]RecName: Full=Lactoylglutathione lyase {ECO:0000256|RuleBase:RU361179}; EC=4.4.1.5 {ECO:0000256|RuleBase:RU361179}; AltName: Full=Glyoxalase I {ECO:0000256|RuleBase:RU361179};+++[X5DNM4_HUMAN|Unreviewed]RecName: Full=Lactoylglutathione lyase {ECO:0000256|RuleBase:RU361179}; EC=4.4.1.5 {ECO:0000256|RuleBase:RU361179}; AltName: Full=Glyoxalase I {ECO:0000256|RuleBase:RU361179}; Flags: Fragment;"]
[2746,"'GLUD1'",869.21,932.87,873.28,891.786666666667,"04217///Necroptosis+++00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++01100///Metabolic pathways+++00471///D-Glutamine and D-glutamate metabolism+++01200///Carbon metabolism+++04964///Proximal tubule bicarbonate reclamation+++00910///Nitrogen metabolism","H01267///Familial hyperinsulinemic hypoglycemia (HHF)+++H01400///Secondary hyperammonemia","M00740///Methylaspartate cycle","R00248///L-Glutamate:NADP+ oxidoreductase (deaminating)   L-Glutamate + NADP+ + H2O <=> 2-Oxoglutarate + Ammonia + NADPH + H++++R00243///L-glutamate:NAD+ oxidoreductase (deaminating)   L-Glutamate + NAD+ + H2O <=> 2-Oxoglutarate + Ammonia + NADH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm","GO:0016639///oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0070403///NAD+ binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0043531///ADP binding+++GO:0004353///glutamate dehydrogenase [NAD(P)+] activity+++GO:0070728///leucine binding+++GO:0016491///oxidoreductase activity+++GO:0005525///GTP binding+++GO:0004352///glutamate dehydrogenase (NAD+) activity","GO:0006538///glutamate catabolic process+++GO:0055114///oxidation-reduction process+++GO:0032024///positive regulation of insulin secretion+++GO:0021762///substantia nigra development+++GO:0006520///cellular amino acid metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0006537///glutamate biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0072350///tricarboxylic acid metabolic process","glutamate dehydrogenase 1","[DHE3_HUMAN|Reviewed]RecName: Full=Glutamate dehydrogenase 1, mitochondrial; Short=GDH 1; EC=1.4.1.3; Flags: Precursor;+++[E9KL48_HUMAN|Unreviewed]SubName: Full=Epididymis tissue sperm binding protein Li 18mP {ECO:0000313|EMBL:ADU87647.1}; SubName: Full=Glutamate dehydrogenase 1, isoform CRA_d {ECO:0000313|EMBL:EAW80304.1};+++[Q14400_HUMAN|Unreviewed]SubName: Full=GLUD1 protein {ECO:0000313|EMBL:AAA52524.1}; Flags: Fragment;+++[Q9UQV0_HUMAN|Unreviewed]SubName: Full=Glutamate dehydrogenase (NAD(P)+) {ECO:0000313|EMBL:CAA46996.1}; EC=1.4.1.3 {ECO:0000313|EMBL:CAA46996.1}; Flags: Fragment;"]
[2782,"'GNB1'",8036,7382,7023,7480.33333333333,"04723///Retrograde endocannabinoid signaling+++04014///Ras signaling pathway+++05200///Pathways in cancer+++04062///Chemokine signaling pathway+++04744///Phototransduction+++05032///Morphine addiction+++04724///Glutamatergic synapse+++05034///Alcoholism+++04727///GABAergic synapse+++04740///Olfactory transduction+++04371///Apelin signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04011///MAPK signaling pathway - yeast+++04151///PI3K-Akt signaling pathway+++04726///Serotonergic synapse+++04728///Dopaminergic synapse+++05163///Human cytomegalovirus infection+++04713///Circadian entrainment+++04926///Relaxin signaling pathway+++04725///Cholinergic synapse","H00773///Autosomal dominant mental retardation",null,null,"GO:0001917///photoreceptor inner segment+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0005834///heterotrimeric G-protein complex+++GO:0044297///cell body+++GO:0001750///photoreceptor outer segment+++GO:0042622///photoreceptor outer segment membrane+++GO:0070062///extracellular exosome+++GO:0005765///lysosomal membrane+++GO:0097381///photoreceptor disc membrane+++GO:1903561///extracellular vesicle+++GO:0005829///cytosol","GO:0044877///protein-containing complex binding+++GO:0030507///spectrin binding+++GO:0051020///GTPase binding+++GO:0047391///alkylglycerophosphoethanolamine phosphodiesterase activity+++GO:0005515///protein binding+++GO:0003924///GTPase activity","GO:0030168///platelet activation+++GO:0007265///Ras protein signal transduction+++GO:0007165///signal transduction+++GO:0071870///cellular response to catecholamine stimulus+++GO:0071456///cellular response to hypoxia+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0060041///retina development in camera-type eye+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050909///sensory perception of taste+++GO:0070208///protein heterotrimerization+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0006457///protein folding+++GO:0008283///cell proliferation+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway","G protein subunit beta 1","[GBB1_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; AltName: Full=Transducin beta chain 1;+++[A0A024R056_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein (G protein), beta polypeptide 1, isoform CRA_a {ECO:0000313|EMBL:EAW56150.1}; SubName: Full=Testicular tissue protein Li 72 {ECO:0000313|EMBL:AEE60985.1};+++[A0A2L0WW42_HUMAN|Unreviewed]SubName: Full=G protein subunit beta 1 {ECO:0000313|EMBL:AVA32057.1};+++[B1AKQ8_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 {ECO:0000313|Ensembl:ENSP00000416651}; Flags: Fragment;+++[B3KVK2_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 {ECO:0000313|Ensembl:ENSP00000483532}; SubName: Full=cDNA FLJ16663 fis, clone THYMU2005759, highly similar to Guanine nucleotide-binding proteinG(I)/G(S)/G(T) subunit beta 1 {ECO:0000313|EMBL:BAG53814.1};+++[F6UT28_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 {ECO:0000313|Ensembl:ENSP00000392765}; Flags: Fragment;+++[F6X3N5_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 {ECO:0000313|Ensembl:ENSP00000399741}; Flags: Fragment;+++[L8E8V9_HUMAN|Unreviewed]SubName: Full=Alternative protein GNB1 {ECO:0000313|EMBL:CCQ43166.1};"]
[2797,"'GNRH2'",0,3,4,2.33333333333333,"04912///GnRH signaling pathway","H00255///Hypogonadotropic hypogonadism",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0031530///gonadotropin-releasing hormone receptor binding+++GO:0005183///gonadotropin hormone-releasing hormone activity+++GO:0005179///hormone activity","GO:0007165///signal transduction+++GO:0000003///reproduction+++GO:0007275///multicellular organism development+++GO:0010469///regulation of signaling receptor activity+++GO:0007186///G protein-coupled receptor signaling pathway","gonadotropin releasing hormone 2","[GON2_HUMAN|Reviewed]RecName: Full=Progonadoliberin-2; AltName: Full=Progonadoliberin II; Contains: RecName: Full=Gonadoliberin-2; AltName: Full=Gonadoliberin II; AltName: Full=Gonadotropin-releasing hormone II; Short=GnRH II; AltName: Full=Luliberin II; AltName: Full=Luteinizing hormone-releasing hormone II; Short=LH-RH II; Contains: RecName: Full=GnRH-associated peptide 2; AltName: Full=GnRH-associated peptide II; Flags: Precursor;"]
[2822,"'GPLD1'",54,47,36,45.6666666666667,"01100///Metabolic pathways+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis","H00835///Succinic semialdehyde dehydrogenase (SSADH) deficiency","M00027///GABA (gamma-Aminobutyrate) shunt","R06623///glycoprotein-phosphatidylinositol phosphatidohydrolase   G00144 + H2O <=> 6-(alpha-D-glucosaminyl)-1D-myo-inositol + Phosphatidate","GO:0005737///cytoplasm+++GO:0005622///intracellular+++GO:0005765///lysosomal membrane+++GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region","GO:0004621///glycosylphosphatidylinositol phospholipase D activity+++GO:0017080///sodium channel regulator activity+++GO:0004630///phospholipase D activity+++GO:0016787///hydrolase activity","GO:0043065///positive regulation of apoptotic process+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0097241///hematopoietic stem cell migration to bone marrow+++GO:1900076///regulation of cellular response to insulin stimulus+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0002062///chondrocyte differentiation+++GO:0010983///positive regulation of high-density lipoprotein particle clearance+++GO:0071401///cellular response to triglyceride+++GO:0032869///cellular response to insulin stimulus+++GO:0071467///cellular response to pH+++GO:0045919///positive regulation of cytolysis+++GO:0046470///phosphatidylcholine metabolic process+++GO:0002430///complement receptor mediated signaling pathway+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0009749///response to glucose+++GO:0010897///negative regulation of triglyceride catabolic process+++GO:0006507///GPI anchor release+++GO:0035690///cellular response to drug+++GO:0010907///positive regulation of glucose metabolic process+++GO:0051047///positive regulation of secretion+++GO:0001503///ossification+++GO:0035701///hematopoietic stem cell migration+++GO:0071277///cellular response to calcium ion+++GO:0010595///positive regulation of endothelial cell migration+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0008286///insulin receptor signaling pathway+++GO:0071397///cellular response to cholesterol+++GO:0006501///C-terminal protein lipidation+++GO:0070633///transepithelial transport+++GO:0008285///negative regulation of cell proliferation","glycosylphosphatidylinositol specific phospholipase D1","[PHLD_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol-glycan-specific phospholipase D; Short=PI-G PLD; EC=3.1.4.50; AltName: Full=Glycoprotein phospholipase D; AltName: Full=Glycosyl-phosphatidylinositol-specific phospholipase D; Short=GPI-PLD; Short=GPI-specific phospholipase D; Flags: Precursor;"]
[282890,"'ZNF311'",44,32,33,36.3333333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 311","[ZN311_HUMAN|Reviewed]RecName: Full=Zinc finger protein 311; AltName: Full=Zinc finger protein zfp-31;+++[A0A1U9X8W3_HUMAN|Unreviewed]SubName: Full=ZNF311 {ECO:0000313|EMBL:AQY77234.1};+++[L0R8L7_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF311 {ECO:0000313|EMBL:CCO13856.1};"]
[283149,"'BCL9L'",6514,6688,6155,6452.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:1990907///beta-catenin-TCF complex+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity+++GO:0008013///beta-catenin binding","GO:0022604///regulation of cell morphogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0035914///skeletal muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0060070///canonical Wnt signaling pathway+++GO:1904837///beta-catenin-TCF complex assembly","B cell CLL/lymphoma 9 like","[BCL9L_HUMAN|Reviewed]RecName: Full=B-cell CLL/lymphoma 9-like protein; Short=B-cell lymphoma 9-like protein; Short=BCL9-like protein; AltName: Full=Protein BCL9-2;+++[A0A087WZX0_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 9-like protein {ECO:0000313|Ensembl:ENSP00000482938};+++[E9PNR0_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 9-like protein {ECO:0000313|Ensembl:ENSP00000432804}; Flags: Fragment;"]
[283385,"'MORN3'",14,13,16,14.3333333333333,"04611///Platelet activation+++04927///Cortisol synthesis and secretion+++04934///Cushing's syndrome+++05340///Primary immunodeficiency+++04024///cAMP signaling pathway+++04924///Renin secretion+++04020///Calcium signaling pathway+++04925///Aldosterone synthesis and secretion","H00093///Combined immunodeficiencies (CIDs)",null,null,"GO:0005634///nucleus","GO:0005515///protein binding","GO:0002250///adaptive immune response+++GO:0070509///calcium ion import+++GO:0061180///mammary gland epithelium development+++GO:0051928///positive regulation of calcium ion transport+++GO:0002115///store-operated calcium entry+++GO:0051924///regulation of calcium ion transport","MORN repeat containing 3","[MORN3_HUMAN|Reviewed]RecName: Full=MORN repeat-containing protein 3;+++[A0A024RBS9_HUMAN|Unreviewed]SubName: Full=MORN repeat containing 3, isoform CRA_a {ECO:0000313|EMBL:EAW98274.1};"]
[283464,"'GXYLT1'",199,229,192,206.666666666667,"00514///Other types of O-glycan biosynthesis",null,null,"R09290///UDP-D-xylose + G13051 <=> UDP + G03532","GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0035252///UDP-xylosyltransferase activity+++GO:0016740///transferase activity","GO:0016266///O-glycan processing","glucoside xylosyltransferase 1","[GXLT1_HUMAN|Reviewed]RecName: Full=Glucoside xylosyltransferase 1; EC=2.4.2.n2; AltName: Full=Glycosyltransferase 8 domain-containing protein 3;"]
[283871,"'PGP'",462,461,437,453.333333333333,"01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites+++01200///Carbon metabolism+++00630///Glyoxylate and dicarboxylate metabolism",null,"M00532///Photorespiration","R01334///2-phosphoglycolate phosphohydrolase   2-Phosphoglycolate + H2O <=> Glycolate + Orthophosphate","GO:0005829///cytosol","GO:0000287///magnesium ion binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0098519///nucleotide phosphatase activity, acting on free nucleotides+++GO:0043136///glycerol-3-phosphatase activity+++GO:0008967///phosphoglycolate phosphatase activity+++GO:0000121///glycerol-1-phosphatase activity","GO:0045721///negative regulation of gluconeogenesis+++GO:0006650///glycerophospholipid metabolic process+++GO:0006114///glycerol biosynthetic process+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0016311///dephosphorylation","phosphoglycolate phosphatase","[PGP_HUMAN|Reviewed]RecName: Full=Glycerol-3-phosphate phosphatase {ECO:0000305}; Short=G3PP {ECO:0000303|PubMed:26755581}; EC=3.1.3.21 {ECO:0000269|PubMed:26755581}; AltName: Full=Aspartate-based ubiquitous Mg(2+)-dependent phosphatase {ECO:0000303|PubMed:26755581}; Short=AUM {ECO:0000303|PubMed:26755581}; EC=3.1.3.48 {ECO:0000250|UniProtKB:Q8CHP8}; AltName: Full=Phosphoglycolate phosphatase {ECO:0000303|PubMed:215071}; Short=PGP {ECO:0000303|PubMed:215071};+++[H3BV17_HUMAN|Unreviewed]SubName: Full=Glycerol-3-phosphate phosphatase {ECO:0000313|Ensembl:ENSP00000457909}; Flags: Fragment;"]
[283989,"'TSEN54'",181,196,172,183,null,"H00897///Pontocerebellar hypoplasia",null,null,"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000214///tRNA-intron endonuclease complex","GO:0005515///protein binding+++GO:0000213///tRNA-intron endonuclease activity","GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0000379///tRNA-type intron splice site recognition and cleavage+++GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0006397///mRNA processing+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation","tRNA splicing endonuclease subunit 54","[SEN54_HUMAN|Reviewed]RecName: Full=tRNA-splicing endonuclease subunit Sen54; AltName: Full=SEN54 homolog; Short=HsSEN54; AltName: Full=tRNA-intron endonuclease Sen54;+++[E7EN92_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen54 {ECO:0000313|Ensembl:ENSP00000406559}; Flags: Fragment;+++[J3KRC5_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen54 {ECO:0000313|Ensembl:ENSP00000461928}; Flags: Fragment;+++[J3QLM6_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen54 {ECO:0000313|Ensembl:ENSP00000463619};+++[J3QRQ5_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen54 {ECO:0000313|Ensembl:ENSP00000464335}; Flags: Fragment;+++[J9JIH8_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen54 {ECO:0000313|Ensembl:ENSP00000438169}; Flags: Fragment;"]
[284086,"'NEK8'",79,111.84,80,90.28,null,"H00537///Nephronophthisis",null,null,"GO:0005929///cilium+++GO:0097546///ciliary base+++GO:0097543///ciliary inversin compartment+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding","GO:0007368///determination of left/right symmetry+++GO:0035330///regulation of hippo signaling+++GO:0016310///phosphorylation+++GO:0009887///animal organ morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007507///heart development","NIMA related kinase 8","[NEK8_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Nek8; EC=2.7.11.1; AltName: Full=Never in mitosis A-related kinase 8; Short=NimA-related protein kinase 8; AltName: Full=Nima-related protein kinase 12a;+++[K7EL04_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek8 {ECO:0000313|Ensembl:ENSP00000465859};+++[K7EMF0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek8 {ECO:0000313|Ensembl:ENSP00000466476}; Flags: Fragment;+++[K7END4_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek8 {ECO:0000313|Ensembl:ENSP00000466896}; Flags: Fragment;+++[K7EPD3_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek8 {ECO:0000313|Ensembl:ENSP00000467335}; Flags: Fragment;"]
[284184,"'NDUFAF8'",532,343,352,409,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0032981///mitochondrial respiratory chain complex I assembly","NADH:ubiquinone oxidoreductase complex assembly factor 8","[NDUF8_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 {ECO:0000312|HGNC:HGNC:33551};+++[I3L4C8_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8 {ECO:0000313|Ensembl:ENSP00000461155}; Flags: Fragment;"]
[284348,"'LYPD5'",47,57,37,47,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region","GO:0043236///laminin binding","GO:0007160///cell-matrix adhesion","LY6/PLAUR domain containing 5","[LYPD5_HUMAN|Reviewed]RecName: Full=Ly6/PLAUR domain-containing protein 5; Flags: Precursor;+++[M0QYY3_HUMAN|Unreviewed]SubName: Full=Ly6/PLAUR domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000470163}; Flags: Fragment;+++[M0R1J4_HUMAN|Unreviewed]SubName: Full=Ly6/PLAUR domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000471909}; Flags: Fragment;"]
[284402,"'SCGB2B2'",16,4,10,10,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region",null,null,"secretoglobin family 2B member 2","[SC2B2_HUMAN|Reviewed]RecName: Full=Secretoglobin family 2B member 2; AltName: Full=Secretoglobin-like protein; Flags: Precursor;"]
[284695,"'ZNF326'",369,484,394,415.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0016363///nuclear matrix+++GO:0005654///nucleoplasm+++GO:0044609///DBIRD complex","GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding+++GO:0046872///metal ion binding","GO:0008380///RNA splicing+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0006397///mRNA processing+++GO:0043484///regulation of RNA splicing","zinc finger protein 326","[ZN326_HUMAN|Reviewed]RecName: Full=DBIRD complex subunit ZNF326; AltName: Full=Zinc finger protein 326; AltName: Full=Zinc finger protein interacting with mRNPs and DBC1;+++[A0A0A0MRN4_HUMAN|Unreviewed]SubName: Full=DBIRD complex subunit ZNF326 {ECO:0000313|Ensembl:ENSP00000359476}; SubName: Full=Zinc finger protein 326, isoform CRA_c {ECO:0000313|EMBL:EAW73127.1};+++[E2QRN4_HUMAN|Unreviewed]SubName: Full=DBIRD complex subunit ZNF326 {ECO:0000313|Ensembl:ENSP00000378084};"]
[285025,"'CCDC141'",7,21.01,9,12.3366666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:0051642///centrosome localization+++GO:0021799///cerebral cortex radially oriented cell migration","coiled-coil domain containing 141","[CC141_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 141; AltName: Full=Coiled-coil protein associated with myosin II and DISC1 {ECO:0000303|PubMed:20956536};+++[A0A0A6YYF7_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 141 {ECO:0000313|Ensembl:ENSP00000344627}; Flags: Fragment;+++[B8ZZB3_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 141 {ECO:0000313|Ensembl:ENSP00000386503};+++[C9JR62_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 141 {ECO:0000313|Ensembl:ENSP00000388745}; Flags: Fragment;+++[E7ERF0_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 141 {ECO:0000313|Ensembl:ENSP00000390190}; Flags: Fragment;+++[Q2VPJ5_HUMAN|Unreviewed]SubName: Full=CCDC141 protein {ECO:0000313|EMBL:AAI08698.1}; Flags: Fragment;"]
[2852,"'GPER1'",216,182,199,199,"04915///Estrogen signaling pathway+++01522///Endocrine resistance",{"$nulls":3},"GO:0005635///nuclear envelope+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0043679///axon terminus+++GO:0030424///axon+++GO:0005769///early endosome+++GO:0045202///synapse+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0031966///mitochondrial membrane+++GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0005886///plasma membrane+++GO:0048786///presynaptic active zone+++GO:0005802///trans-Golgi network+++GO:0043198///dendritic shaft+++GO:0000139///Golgi membrane+++GO:0055037///recycling endosome+++GO:0032591///dendritic spine membrane+++GO:0005737///cytoplasm+++GO:0045095///keratin filament+++GO:0044327///dendritic spine head+++GO:0042995///cell projection+++GO:0005622///intracellular+++GO:0016021///integral component of membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0014069///postsynaptic density+++GO:0031410///cytoplasmic vesicle","GO:1990239///steroid hormone binding+++GO:0005515///protein binding+++GO:0005496///steroid binding+++GO:0017082///mineralocorticoid receptor activity+++GO:0003682///chromatin binding+++GO:0004930///G protein-coupled receptor activity+++GO:0030284///estrogen receptor activity","GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045599///negative regulation of fat cell differentiation+++GO:0030264///nuclear fragmentation involved in apoptotic nuclear change+++GO:0043410///positive regulation of MAPK cascade+++GO:0010628///positive regulation of gene expression+++GO:0007399///nervous system development+++GO:0050728///negative regulation of inflammatory response+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0007165///signal transduction+++GO:0071333///cellular response to glucose stimulus+++GO:0050804///modulation of chemical synaptic transmission+++GO:0006915///apoptotic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0002695///negative regulation of leukocyte activation+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0045087///innate immune response+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0030154///cell differentiation+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:0071157///negative regulation of cell cycle arrest+++GO:0043065///positive regulation of apoptotic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0050769///positive regulation of neurogenesis+++GO:0071392///cellular response to estradiol stimulus+++GO:0001934///positive regulation of protein phosphorylation+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0097755///positive regulation of blood vessel diameter+++GO:0008285///negative regulation of cell proliferation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0071389///cellular response to mineralocorticoid stimulus+++GO:0019228///neuronal action potential+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:2000724///positive regulation of cardiac vascular smooth muscle cell differentiation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007049///cell cycle+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0002376///immune system process+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0031959///mineralocorticoid receptor signaling pathway+++GO:0032024///positive regulation of insulin secretion+++GO:0030263///apoptotic chromosome condensation+++GO:0010629///negative regulation of gene expression+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0051053///negative regulation of DNA metabolic process+++GO:0006954///inflammatory response+++GO:0010948///negative regulation of cell cycle process","G protein-coupled estrogen receptor 1","[GPER1_HUMAN|Reviewed]RecName: Full=G-protein coupled estrogen receptor 1; AltName: Full=Chemoattractant receptor-like 2; AltName: Full=Flow-induced endothelial G-protein coupled receptor 1; Short=FEG-1; AltName: Full=G protein-coupled estrogen receptor 1; AltName: Full=G-protein coupled receptor 30; AltName: Full=GPCR-Br; AltName: Full=IL8-related receptor DRY12; AltName: Full=Lymphocyte-derived G-protein coupled receptor; Short=LYGPR; AltName: Full=Membrane estrogen receptor; Short=mER;+++[A0A024R849_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 30, isoform CRA_a {ECO:0000313|EMBL:EAW87195.1};+++[A0A087WVN0_HUMAN|Unreviewed]SubName: Full=G-protein-coupled estrogen receptor 1 {ECO:0000313|Ensembl:ENSP00000479553};+++[A0A087X0Z4_HUMAN|Unreviewed]SubName: Full=G-protein-coupled estrogen receptor 1 {ECO:0000313|Ensembl:ENSP00000483756};+++[C9J3W2_HUMAN|Unreviewed]SubName: Full=G-protein-coupled estrogen receptor 1 {ECO:0000313|Ensembl:ENSP00000410487}; Flags: Fragment;+++[Q63ZY2_HUMAN|Unreviewed]SubName: Full=GPER protein {ECO:0000313|EMBL:AAH82766.1};+++[Q6FHU6_HUMAN|Unreviewed]SubName: Full=GPR30 protein {ECO:0000313|EMBL:CAG46456.1}; Flags: Fragment;"]
[285386,"'TPRG1'",6,5,6,5.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination","tumor protein p63 regulated 1","[TPRG1_HUMAN|Reviewed]RecName: Full=Tumor protein p63-regulated gene 1 protein; AltName: Full=Protein FAM79B;+++[C9IYC1_HUMAN|Unreviewed]SubName: Full=Tumor protein p63-regulated gene 1 protein {ECO:0000313|Ensembl:ENSP00000399133}; Flags: Fragment;+++[C9JDW1_HUMAN|Unreviewed]SubName: Full=Tumor protein p63-regulated gene 1 protein {ECO:0000313|Ensembl:ENSP00000415413}; Flags: Fragment;+++[H7C1G4_HUMAN|Unreviewed]SubName: Full=Tumor protein p63-regulated gene 1 protein {ECO:0000313|Ensembl:ENSP00000400171}; Flags: Fragment;"]
[285556,"'C4orf54'",7,4,5,5.33333333333333,{"$nulls":7},"chromosome 4 open reading frame 54","[CD054_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C4orf54 {ECO:0000305}; AltName: Full=Familial obliterative portal venopathy {ECO:0000303|PubMed:28792652};"]
[285755,"'PPIL6'",62.15,40,56,52.7166666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005794///Golgi apparatus","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0051082///unfolded protein binding","GO:0000413///protein peptidyl-prolyl isomerization","peptidylprolyl isomerase like 6","[PPIL6_HUMAN|Reviewed]RecName: Full=Problable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000305|PubMed:20676357}; Short=PPIase {ECO:0000305|PubMed:20676357}; AltName: Full=Cyclophilin-like protein PPIL6 {ECO:0000312|EMBL:ABC88651.1}; AltName: Full=Rotamase PPIL6;+++[B4DEK6_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[H0Y7C3_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[H0YAQ8_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[H0YC62_HUMAN|Unreviewed]SubName: Full=Problable inactive peptidyl-prolyl cis-trans isomerase-like 6 {ECO:0000313|Ensembl:ENSP00000430998}; Flags: Fragment;+++[Q8TAE1_HUMAN|Unreviewed]SubName: Full=PPIL6 protein {ECO:0000313|EMBL:AAH26359.2};"]
[286075,"'ZNF707'",152,127,143,140.666666666667,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 707","[ZN707_HUMAN|Reviewed]RecName: Full=Zinc finger protein 707;+++[A0A2R8YE36_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000495224};+++[E9PHZ0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000436634}; Flags: Fragment;+++[E9PJ46_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000435679};+++[E9PKX4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000435251};+++[E9PNV7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000437134}; Flags: Fragment;+++[E9PP66_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000436394};+++[E9PPS7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000436362}; Flags: Fragment;+++[E9PQ20_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000434503}; Flags: Fragment;+++[E9PS67_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 707 {ECO:0000313|Ensembl:ENSP00000435906}; Flags: Fragment;"]
[286257,"'PAXX'",260,300,236,265.333333333333,{"$nulls":4},"GO:0043564///Ku70:Ku80 complex+++GO:0035861///site of double-strand break+++GO:0070419///nonhomologous end joining complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity","GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051103///DNA ligation involved in DNA repair","PAXX, non-homologous end joining factor","[PAXX_HUMAN|Reviewed]RecName: Full=Protein PAXX {ECO:0000305}; AltName: Full=Paralog of XRCC4 and XLF {ECO:0000303|PubMed:25574025}; AltName: Full=XRCC4-like small protein {ECO:0000303|PubMed:25941166};"]
[286749,"'STON1-GTF2A1L'",11.83,14.76,25.4,17.33,{"$nulls":4},"GO:0016020///membrane+++GO:0005672///transcription factor TFIIA complex",null,"GO:0006897///endocytosis+++GO:0030100///regulation of endocytosis+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter","STON1-GTF2A1L readthrough","[STON1_HUMAN|Reviewed]RecName: Full=Stonin-1; AltName: Full=Stoned B-like factor;+++[A0A0A6YYG5_HUMAN|Unreviewed]SubName: Full=Protein STON1-GTF2A1L {ECO:0000313|Ensembl:ENSP00000378234};+++[Q3MIM1_HUMAN|Unreviewed]SubName: Full=STON1-GTF2A1L readthrough transcript {ECO:0000313|EMBL:AAI01775.1};+++[Q53S48_HUMAN|Unreviewed]SubName: Full=STON1-GTF2A1L readthrough {ECO:0000313|Ensembl:ENSP00000378236};"]
[2886,"'GRB7'",389,460,419,422.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0010494///cytoplasmic stress granule+++GO:0042995///cell projection+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0019901///protein kinase binding+++GO:0035091///phosphatidylinositol binding+++GO:0005515///protein binding","GO:0050900///leukocyte migration+++GO:0034063///stress granule assembly+++GO:0030335///positive regulation of cell migration+++GO:0007411///axon guidance+++GO:0007165///signal transduction+++GO:0038128///ERBB2 signaling pathway+++GO:0017148///negative regulation of translation+++GO:0009967///positive regulation of signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway","growth factor receptor bound protein 7","[GRB7_HUMAN|Reviewed]RecName: Full=Growth factor receptor-bound protein 7; AltName: Full=B47; AltName: Full=Epidermal growth factor receptor GRB-7; AltName: Full=GRB7 adapter protein;+++[A0A0S2Z3V3_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 7 isoform 2 {ECO:0000313|EMBL:ALQ33562.1};+++[A0A0S2Z4F6_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 7 isoform 1 {ECO:0000313|EMBL:ALQ33561.1}; Flags: Fragment;+++[J3QKK7_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 7 {ECO:0000313|Ensembl:ENSP00000463126};+++[J3QL76_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 7 {ECO:0000313|Ensembl:ENSP00000463416}; Flags: Fragment;"]
[28957,"'MRPS28'",72,55,86,71,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005763///mitochondrial small ribosomal subunit","GO:0003964///RNA-directed DNA polymerase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0070126///mitochondrial translational termination+++GO:0032197///transposition, RNA-mediated+++GO:0070125///mitochondrial translational elongation+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","mitochondrial ribosomal protein S28","[RT28_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S28, mitochondrial; Short=MRP-S28; Short=S28mt; AltName: Full=28S ribosomal protein S35, mitochondrial; Short=MRP-S35; Short=S35mt; AltName: Full=Mitochondrial small ribosomal subunit protein bS1m {ECO:0000303|PubMed:25838379}; Flags: Precursor;+++[A0A0S2Z563_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein S28 isoform 1 {ECO:0000313|EMBL:ALQ34070.1}; Flags: Fragment;"]
[28974,"'C19orf53'",1927,1944,1862,1911,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus",null,null,"chromosome 19 open reading frame 53","[L10K_HUMAN|Reviewed]RecName: Full=Leydig cell tumor 10 kDa protein homolog;+++[A0A0A0MQS3_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000221576}; Flags: Fragment;+++[K7EIU1_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000464891}; Flags: Fragment;+++[K7EN09_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000466736}; Flags: Fragment;+++[K7ESE5_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000468676};"]
[28999,"'KLF15'",85,183,126,131.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding","GO:0010001///glial cell differentiation+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000757///negative regulation of peptidyl-lysine acetylation+++GO:0046326///positive regulation of glucose import+++GO:0032868///response to insulin+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0001678///cellular glucose homeostasis","Kruppel like factor 15","[KLF15_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 15; AltName: Full=Kidney-enriched krueppel-like factor;"]
[2906,"'GRIN2D'",73,66,57,65.3333333333333,"04713///Circadian entrainment+++04724///Glutamatergic synapse+++04020///Calcium signaling pathway+++05031///Amphetamine addiction+++04024///cAMP signaling pathway+++05033///Nicotine addiction+++05010///Alzheimer's disease+++04720///Long-term potentiation+++05034///Alcoholism+++04080///Neuroactive ligand-receptor interaction+++05030///Cocaine addiction+++05014///Amyotrophic lateral sclerosis (ALS)","H00606///Early infantile epileptic encephalopathy",null,null,"GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0017146///NMDA selective glutamate receptor complex+++GO:0098839///postsynaptic density membrane+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0045211///postsynaptic membrane","GO:0004972///NMDA glutamate receptor activity+++GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0005515///protein binding+++GO:0022849///glutamate-gated calcium ion channel activity+++GO:0038023///signaling receptor activity","GO:0097553///calcium ion transmembrane import into cytosol+++GO:0098976///excitatory chemical synaptic transmission+++GO:0001964///startle response+++GO:0051930///regulation of sensory perception of pain+++GO:0048167///regulation of synaptic plasticity+++GO:0008344///adult locomotory behavior+++GO:0060291///long-term synaptic potentiation+++GO:0007420///brain development+++GO:0006811///ion transport+++GO:0060079///excitatory postsynaptic potential+++GO:0019722///calcium-mediated signaling+++GO:0035235///ionotropic glutamate receptor signaling pathway","glutamate ionotropic receptor NMDA type subunit 2D","[NMDE4_HUMAN|Reviewed]RecName: Full=Glutamate receptor ionotropic, NMDA 2D; Short=GluN2D; AltName: Full=EB11; AltName: Full=Glutamate [NMDA] receptor subunit epsilon-4; AltName: Full=N-methyl D-aspartate receptor subtype 2D; Short=NMDAR2D; Short=NR2D; Flags: Precursor;+++[Q59G17_HUMAN|Unreviewed]SubName: Full=N-methyl-D-aspartate receptor subunit 2D variant {ECO:0000313|EMBL:BAD92529.1}; Flags: Fragment;"]
[29068,"'ZBTB44'",403,356,357,372,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 44","[ZBT44_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 44; AltName: Full=BTB/POZ domain-containing protein 15; AltName: Full=Zinc finger protein 851;+++[A0A0A0MTE9_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000435413}; Flags: Fragment;+++[H0YCZ0_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000432558}; Flags: Fragment;+++[H0YEM9_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000436187}; Flags: Fragment;+++[H7BY22_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000350574};"]
[291,"'SLC25A4'",1291,1166,1102,1186.33333333333,"04217///Necroptosis+++05012///Parkinson's disease+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04218///Cellular senescence+++05016///Huntington's disease+++05166///HTLV-I infection","H00469///Mitochondrial DNA depletion syndrome (MDS)+++H01118///Progressive external ophthalmoplegia (PEO)",null,null,"GO:0043209///myelin sheath+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0005887///integral component of plasma membrane","GO:0022857///transmembrane transporter activity+++GO:0005471///ATP:ADP antiporter activity+++GO:0015207///adenine transmembrane transporter activity+++GO:0005515///protein binding","GO:0015866///ADP transport+++GO:0015867///ATP transport+++GO:0060546///negative regulation of necroptotic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0016032///viral process+++GO:0008637///apoptotic mitochondrial changes+++GO:0050796///regulation of insulin secretion+++GO:0000002///mitochondrial genome maintenance+++GO:0055085///transmembrane transport+++GO:0015853///adenine transport","solute carrier family 25 member 4","[ADT1_HUMAN|Reviewed]RecName: Full=ADP/ATP translocase 1; AltName: Full=ADP,ATP carrier protein 1; AltName: Full=ADP,ATP carrier protein, heart/skeletal muscle isoform T1; AltName: Full=Adenine nucleotide translocator 1; Short=ANT 1; AltName: Full=Solute carrier family 25 member 4;+++[A0A0S2Z359_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 4 isoform 3 {ECO:0000313|EMBL:ALQ33360.1}; Flags: Fragment;+++[A0A0S2Z3C4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 4 isoform 2 {ECO:0000313|EMBL:ALQ33359.1}; Flags: Fragment;+++[A0A0S2Z3H3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 4 isoform 1 {ECO:0000313|EMBL:ALQ33358.1}; Flags: Fragment;+++[V9GYG0_HUMAN|Unreviewed]SubName: Full=ADP/ATP translocase 1 {ECO:0000313|Ensembl:ENSP00000476711};"]
[29118,"'DDX25'",9,5,8,7.33333333333333,null,"H01265///Hydrolethalus syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0033391///chromatoid body","GO:0004386///helicase activity+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding","GO:0007275///multicellular organism development+++GO:0006406///mRNA export from nucleus+++GO:0006417///regulation of translation+++GO:0051028///mRNA transport+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0007283///spermatogenesis","DEAD-box helicase 25","[DDX25_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX25; EC=3.6.4.13; AltName: Full=DEAD box protein 25; AltName: Full=Gonadotropin-regulated testicular RNA helicase;+++[A0A1B0GV69_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX25 {ECO:0000313|Ensembl:ENSP00000490392};+++[B4YF11_HUMAN|Unreviewed]SubName: Full=DDX25 {ECO:0000313|EMBL:ACA64098.1}; Flags: Fragment;+++[E9PR46_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX25 {ECO:0000313|Ensembl:ENSP00000436087}; Flags: Fragment;+++[H0YD26_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX25 {ECO:0000313|Ensembl:ENSP00000432800}; Flags: Fragment;+++[J3QL17_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX25 {ECO:0000313|Ensembl:ENSP00000463333}; Flags: Fragment;+++[J3QRJ6_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX25 {ECO:0000313|Ensembl:ENSP00000464251}; Flags: Fragment;"]
[29125,"'C11orf21'",1,1,0,0.666666666666667,{"$nulls":4},"GO:0005737///cytoplasm",null,"GO:0007166///cell surface receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007229///integrin-mediated signaling pathway+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0042832///defense response to protozoan+++GO:0007010///cytoskeleton organization+++GO:0070527///platelet aggregation+++GO:0008285///negative regulation of cell proliferation+++GO:0050688///regulation of defense response to virus","chromosome 11 open reading frame 21","[CK021_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf21;+++[E9PAM5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf21 {ECO:0000313|Ensembl:ENSP00000406541};"]
[2944,"'GSTM1'",0,2.8,1.51,1.43666666666667,"05204///Chemical carcinogenesis+++01524///Platinum drug resistance+++00983///Drug metabolism - other enzymes+++00480///Glutathione metabolism+++05200///Pathways in cancer+++05418///Fluid shear stress and atherosclerosis+++05225///Hepatocellular carcinoma+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450","H00024///Prostate cancer+++H00516///Cleft lip and/or cleft palate",null,"R07092///1,1-dichloroethylene-epoxide:glutathione S-(chloroepoxyethyl)transferase [2-(S-glutathionyl)acetyl-chloride-forming]   1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid+++R07003///(1R)-glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene+++R09409///glutathione-S-transferase   Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH+++R07093///chloroacetyl-chloride:glutathione S-chloroacetyltransferase   Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid+++R07100///trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase   Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid+++R07116///2-bromoacetaldehyde:glutathione S-(formylmethyl)transferase   2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid+++R03522///RX:glutathione R-transferase   RX + Glutathione <=> Halide + R-S-Glutathione+++R11905///Hepatotoxins + Glutathione <=> R-S-Glutathione+++R07025///1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene+++R07069///3,4-dihydro-3-hydroxy-4-S-glutathionyl bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene+++R07113///1,2-dibromoethane:glutathione ethylenetransferase (episulfonium-forming)   1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid+++R07083///4,5-dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene glutathione-lyase (epoxide-forming)   Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene+++R07002///(1R)-hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene+++R07026///1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene+++R07094///2-(S-glutathionyl)acetyl-chloride:glutathione 2-(S-glutathionyl)acetyltransferase   2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid+++R07023///1-nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene+++R07091///S-(2,2-dichloro-1-hydroxy)ethyl-glutathione 2,2-dichloroacetaldehyde-lyase (glutathione-forming)   2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione+++R08280///4-glutathionyl cyclophosphamide hydrolase   Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O+++R07070///2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene+++R07024///1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene+++R07084///7,8-dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene hydrolase   Benzo[a]pyrene-7,8-diol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O+++R07004///(1S)-hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene","GO:0005737///cytoplasm+++GO:0045171///intercellular bridge+++GO:0005829///cytosol","GO:0043295///glutathione binding+++GO:0004364///glutathione transferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0019899///enzyme binding","GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:1901687///glutathione derivative biosynthetic process+++GO:0006749///glutathione metabolic process+++GO:0070458///cellular detoxification of nitrogen compound","glutathione S-transferase mu 1","[GSTM1_HUMAN|Reviewed]RecName: Full=Glutathione S-transferase Mu 1; EC=2.5.1.18; AltName: Full=GST HB subunit 4; AltName: Full=GST class-mu 1; AltName: Full=GSTM1-1; AltName: Full=GSTM1a-1a; AltName: Full=GSTM1b-1b; AltName: Full=GTH4;+++[B9ZVX7_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase Mu 1 {ECO:0000313|Ensembl:ENSP00000358834};+++[E7EWW9_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase Mu 1 {ECO:0000313|Ensembl:ENSP00000358838};+++[H3BQT3_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase Mu 1 {ECO:0000313|Ensembl:ENSP00000455929}; SubName: Full=Glutathione S-transferase mu 1 isoform E {ECO:0000313|EMBL:AHW56638.1};+++[H3BRM6_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase Mu 1 {ECO:0000313|Ensembl:ENSP00000456315}; Flags: Fragment;+++[Q16041_HUMAN|Unreviewed]SubName: Full=GSTM1 protein {ECO:0000313|EMBL:AAD13938.1}; Flags: Fragment;+++[X5D7U4_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase mu 1 isoform A {ECO:0000313|EMBL:AHW56660.1};+++[X5D932_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase mu 1 isoform C {ECO:0000313|EMBL:AHW56498.1}; Flags: Fragment;+++[X5DNN9_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase mu 1 isoform D {ECO:0000313|EMBL:AHW56496.1}; Flags: Fragment;+++[X5DR03_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase mu 1 isoform B {ECO:0000313|EMBL:AHW56497.1}; Flags: Fragment;"]
[2956,"'MSH6'",466,514,504,494.666666666667,"03430///Mismatch repair+++05200///Pathways in cancer+++05210///Colorectal cancer+++01524///Platinum drug resistance","H00020///Colorectal cancer+++H00876///Mismatch repair deficiency","M00295///BRCA1-associated genome surveillance complex (BASC)",null,"GO:0032301///MutSalpha complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0000790///nuclear chromatin+++GO:0032300///mismatch repair complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm","GO:0032137///guanine/thymine mispair binding+++GO:0000287///magnesium ion binding+++GO:0019899///enzyme binding+++GO:0032405///MutLalpha complex binding+++GO:0003690///double-stranded DNA binding+++GO:0043531///ADP binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0016887///ATPase activity+++GO:0000400///four-way junction DNA binding+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding+++GO:0032143///single thymine insertion binding+++GO:0035064///methylated histone binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0032142///single guanine insertion binding+++GO:0030983///mismatched DNA binding+++GO:0005524///ATP binding+++GO:0032357///oxidized purine DNA binding+++GO:0003684///damaged DNA binding","GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0051096///positive regulation of helicase activity+++GO:0043570///maintenance of DNA repeat elements+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0008340///determination of adult lifespan+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0032876///negative regulation of DNA endoreduplication+++GO:0006298///mismatch repair+++GO:0016032///viral process+++GO:0009411///response to UV+++GO:0043111///replication fork arrest+++GO:0045190///isotype switching+++GO:0016447///somatic recombination of immunoglobulin gene segments+++GO:0045910///negative regulation of DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045830///positive regulation of isotype switching+++GO:0000710///meiotic mismatch repair+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0006290///pyrimidine dimer repair","mutS homolog 6","[MSH6_HUMAN|Reviewed]RecName: Full=DNA mismatch repair protein Msh6 {ECO:0000250|UniProtKB:P54276}; Short=hMSH6 {ECO:0000303|PubMed:8942985}; AltName: Full=G/T mismatch-binding protein {ECO:0000303|PubMed:7604265}; Short=GTBP {ECO:0000303|PubMed:9455487}; Short=GTMBP {ECO:0000250|UniProtKB:P54276}; AltName: Full=MutS protein homolog 6 {ECO:0000312|HGNC:HGNC:7329}; AltName: Full=MutS-alpha 160 kDa subunit; Short=p160 {ECO:0000303|PubMed:7604264};+++[A0A087WWJ1_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000480261};+++[A0A087WYT6_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000482078};+++[C9J7Y7_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000406248}; Flags: Fragment;+++[C9J8Y8_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000397484}; Flags: Fragment;+++[C9JH55_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000390382}; Flags: Fragment;+++[F8W7G9_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000410570};+++[F8WAX8_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000405294};+++[Q1L838_HUMAN|Unreviewed]SubName: Full=GTBP-ALT {ECO:0000313|EMBL:BAA23673.1};+++[Q3SWU9_HUMAN|Unreviewed]SubName: Full=MSH6 protein {ECO:0000313|EMBL:AAI04666.1}; Flags: Fragment;+++[U3KQ72_HUMAN|Unreviewed]SubName: Full=DNA mismatch repair protein Msh6 {ECO:0000313|Ensembl:ENSP00000475605}; Flags: Fragment;"]
[29775,"'CARD10'",351,454,366,390.333333333333,"04064///NF-kappa B signaling pathway",{"$nulls":3},"GO:0032449///CBM complex+++GO:0005737///cytoplasm","GO:0030159///receptor signaling complex scaffold activity+++GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0042981///regulation of apoptotic process","caspase recruitment domain family member 10","[CAR10_HUMAN|Reviewed]RecName: Full=Caspase recruitment domain-containing protein 10; AltName: Full=CARD-containing MAGUK protein 3; Short=Carma 3;+++[B0QYC3_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000393411}; Flags: Fragment;+++[B0QYC4_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000416239}; Flags: Fragment;+++[Q17RA1_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 10 {ECO:0000313|EMBL:AAI17404.1};"]
[29777,"'ABT1'",214,225,217,218.666666666667,{"$nulls":4},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0000472///endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0021522///spinal cord motor neuron differentiation+++GO:0034462///small-subunit processome assembly+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006366///transcription by RNA polymerase II","activator of basal transcription 1","[ABT1_HUMAN|Reviewed]RecName: Full=Activator of basal transcription 1; Short=hABT1; AltName: Full=Basal transcriptional activator;+++[A0A024R029_HUMAN|Unreviewed]SubName: Full=Activator of basal transcription 1, isoform CRA_a {ECO:0000313|EMBL:EAW55593.1};"]
[29881,"'NPC1L1'",1,1,0,0.666666666666667,"04975///Fat digestion and absorption",{"$nulls":3},"GO:0016324///apical plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005886///plasma membrane+++GO:0031526///brush border membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0044214///spanning component of plasma membrane+++GO:0016021///integral component of membrane","GO:0017137///Rab GTPase binding+++GO:0031489///myosin V binding+++GO:0005515///protein binding+++GO:0008144///drug binding+++GO:0005319///lipid transporter activity","GO:0030301///cholesterol transport+++GO:0042493///response to drug+++GO:0008203///cholesterol metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006869///lipid transport+++GO:0030299///intestinal cholesterol absorption+++GO:0098856///intestinal lipid absorption+++GO:0006629///lipid metabolic process+++GO:0071501///cellular response to sterol depletion+++GO:0042157///lipoprotein metabolic process+++GO:0008202///steroid metabolic process","NPC1 like intracellular cholesterol transporter 1","[NPCL1_HUMAN|Reviewed]RecName: Full=NPC1-like intracellular cholesterol transporter 1 {ECO:0000312|HGNC:HGNC:7898}; AltName: Full=Niemann-Pick C1-like protein 1 {ECO:0000303|PubMed:10783261}; Flags: Precursor;+++[A0A0C4DFX6_HUMAN|Unreviewed]SubName: Full=NPC1-like intracellular cholesterol transporter 1 {ECO:0000313|Ensembl:ENSP00000370552};+++[A0A0C4DGG6_HUMAN|Unreviewed]SubName: Full=NPC1-like intracellular cholesterol transporter 1 {ECO:0000313|Ensembl:ENSP00000438033};"]
[29890,"'RBM15B'",1926,1978,1978,1960.66666666667,{"$nulls":4},"GO:0005635///nuclear envelope+++GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0036396///RNA N6-methyladenosine methyltransferase complex","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0006913///nucleocytoplasmic transport+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0016032///viral process+++GO:0008380///RNA splicing+++GO:0006406///mRNA export from nucleus+++GO:0001510///RNA methylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 15B","[RB15B_HUMAN|Reviewed]RecName: Full=Putative RNA-binding protein 15B {ECO:0000305}; AltName: Full=One-twenty two protein 3 {ECO:0000303|PubMed:16129689, ECO:0000303|PubMed:19586903}; Short=HsOTT3 {ECO:0000303|PubMed:19586903}; Short=HuOTT3 {ECO:0000303|PubMed:16129689}; AltName: Full=RNA-binding motif protein 15B {ECO:0000303|PubMed:19586903};+++[L8EAN0_HUMAN|Unreviewed]SubName: Full=Alternative protein RBM15B {ECO:0000313|EMBL:CCQ43418.1};+++[Q0VA89_HUMAN|Unreviewed]SubName: Full=RBM15B protein {ECO:0000313|EMBL:AAI21185.1};"]
[29928,"'TIMM22'",284,269,285,279.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0042721///TIM22 mitochondrial import inner membrane insertion complex","GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0030943///mitochondrion targeting sequence binding","GO:0015031///protein transport+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0006626///protein targeting to mitochondrion","translocase of inner mitochondrial membrane 22","[TIM22_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim22; AltName: Full=Testis-expressed protein 4;"]
[2994,"'GYPB'",2,2,0,1.33333333333333,"05144///Malaria",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0050900///leukocyte migration","glycophorin B (MNS blood group)","[GLPB_HUMAN|Reviewed]RecName: Full=Glycophorin-B; AltName: Full=PAS-3; AltName: Full=SS-active sialoglycoprotein; AltName: Full=Sialoglycoprotein delta; AltName: CD_antigen=CD235b; Flags: Precursor;+++[A0A1E1JP39_HUMAN|Unreviewed]SubName: Full=Glycophorin B, blood group system Ss, S {ECO:0000313|EMBL:CUI25652.1};+++[A0A1E1JP42_HUMAN|Unreviewed]SubName: Full=Glycophorin B, blood group system Ss, S, Mit {ECO:0000313|EMBL:CUI25651.1};+++[A0A1E1JP59_HUMAN|Unreviewed]SubName: Full=Glycophorin B, blood group system Ss, S {ECO:0000313|EMBL:CUI25649.1};+++[A0A1E1JSF8_HUMAN|Unreviewed]SubName: Full=Glycophorin B, blood group system Ss, S {ECO:0000313|EMBL:CUI25650.1};+++[A0A1S5RQQ5_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AOG75403.1}; Flags: Fragment;+++[A0A1W2PQZ9_HUMAN|Unreviewed]RecName: Full=Glycophorin {ECO:0000256|PIRNR:PIRNR002466};+++[A0A223IA98_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AST61830.1}; Flags: Fragment;+++[A0A2D1QUX3_HUMAN|Unreviewed]SubName: Full=Glycophorin B blood group antigen {ECO:0000313|EMBL:ATP16325.1}; Flags: Fragment;+++[A8YPG6_HUMAN|Unreviewed]SubName: Full=Glycophorin B(MNS bloodgroup) {ECO:0000313|EMBL:CAP12645.1}; Flags: Fragment;+++[B8Q175_HUMAN|Unreviewed]SubName: Full=Glycophorin B Miltenberger subtype III {ECO:0000313|EMBL:ACA96787.1};+++[B8Q176_HUMAN|Unreviewed]RecName: Full=Glycophorin {ECO:0000256|PIRNR:PIRNR002466};+++[B8Q177_HUMAN|Unreviewed]SubName: Full=Glycophorin B Miltenberger subtype III {ECO:0000313|EMBL:ACA96784.1};+++[B8Q178_HUMAN|Unreviewed]SubName: Full=Glycophorin B Miltenberger subtype III {ECO:0000313|EMBL:ACA96785.1}; Flags: Fragment;+++[B8Q179_HUMAN|Unreviewed]SubName: Full=Glycophorin B Miltenberger subtype III {ECO:0000313|EMBL:ACA96786.1};+++[B8Q181_HUMAN|Unreviewed]SubName: Full=Glycophorin B Miltenberger subtype III {ECO:0000313|EMBL:ACA96788.1}; Flags: Fragment;+++[B8Q188_HUMAN|Unreviewed]SubName: Full=Glycophorin B MNS blood group {ECO:0000313|EMBL:ACA96795.1};+++[B8Q189_HUMAN|Unreviewed]SubName: Full=Glycophorin B MNS blood group {ECO:0000313|EMBL:ACA96796.1};+++[D6RA87_HUMAN|Unreviewed]SubName: Full=Glycophorin-B {ECO:0000313|Ensembl:ENSP00000423055};+++[D6RAD9_HUMAN|Unreviewed]SubName: Full=Glycophorin-B {ECO:0000313|Ensembl:ENSP00000422726};+++[D6RBP2_HUMAN|Unreviewed]SubName: Full=Glycophorin-B {ECO:0000313|Ensembl:ENSP00000424025};+++[E7ERJ5_HUMAN|Unreviewed]SubName: Full=Glycophorin-B {ECO:0000313|Ensembl:ENSP00000394200};+++[E9NHG6_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:ADW83740.1}; Flags: Fragment;+++[E9NHI4_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:ADW83758.1}; Flags: Fragment;+++[E9NHJ1_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:ADW83765.1}; Flags: Fragment;+++[G8CWH2_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AEP34336.1}; Flags: Fragment;+++[G8CWL5_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AEP34379.1}; Flags: Fragment;+++[G8CWM7_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AEP34391.1}; Flags: Fragment;+++[G8CWQ3_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AEP34417.1}; Flags: Fragment;+++[G8CWU7_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AEP34461.1}; Flags: Fragment;+++[G8CWY9_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AEP34503.1}; Flags: Fragment;+++[G8CWZ8_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AEP34512.1}; Flags: Fragment;+++[H6TMT7_HUMAN|Unreviewed]SubName: Full=Glycophorin B variant MiIII {ECO:0000313|EMBL:AFB71207.2}; Flags: Fragment;+++[Q14461_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AAA53152.1}; Flags: Fragment;+++[Q53X25_HUMAN|Unreviewed]SubName: Full=Glycophorin A {ECO:0000313|EMBL:AAC41695.1}; SubName: Full=Glycophorin B {ECO:0000313|EMBL:AAC41696.1}; Flags: Fragment;+++[Q6R6M5_HUMAN|Unreviewed]SubName: Full=Glycophorin B HE.NY variant {ECO:0000313|EMBL:AAR97608.1};+++[Q6R6M6_HUMAN|Unreviewed]SubName: Full=Glycophorin B NY variant {ECO:0000313|EMBL:AAR97607.1};+++[Q6WBF6_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AAR06000.1}; Flags: Fragment;+++[Q7LDD6_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:AAR06004.1}; SubName: Full=Glycophorin MiIII {ECO:0000313|EMBL:AAC36314.1}; Flags: Fragment;+++[Q8WTQ3_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:CAC83873.1}; Flags: Fragment;+++[Q8WWP0_HUMAN|Unreviewed]SubName: Full=Glycophorin B {ECO:0000313|EMBL:CAC83875.1}; Flags: Fragment;+++[S6FBR6_HUMAN|Unreviewed]SubName: Full=Glycophorin B (MNS bloodgroup) {ECO:0000313|EMBL:CDG15324.1}; Flags: Fragment;+++[V5NV32_HUMAN|Unreviewed]SubName: Full=Hybrid glycophorin Kip {ECO:0000313|EMBL:AHA92088.2}; Flags: Fragment;+++[W0LL28_HUMAN|Unreviewed]SubName: Full=Glycophorin B variant MiIII {ECO:0000313|EMBL:AHG23042.1}; Flags: Fragment;"]
[29954,"'POMT2'",858,878,869,868.333333333333,"00515///Mannose type O-glycan biosynthesis+++01100///Metabolic pathways+++00514///Other types of O-glycan biosynthesis","H01960///Muscular dystrophy-dystroglycanopathy type B+++H01959///Muscular dystrophy-dystroglycanopathy type C+++H00590///Congenital muscular dystrophies (CMD/MDC)+++H00593///Limb-girdle muscular dystrophy (LGMD)+++H00120///Muscular dystrophy-dystroglycanopathy type A",null,"R04072///dolichyl-beta-D-mannosyl-phosphate:protein-serine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]+++R11399///dolichyl-beta-D-mannosyl-phosphate:protein-threonine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein]+++R07620///Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000030///mannosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0016740///transferase activity","GO:0097502///mannosylation+++GO:0006486///protein glycosylation+++GO:1904100///positive regulation of protein O-linked glycosylation+++GO:0006493///protein O-linked glycosylation+++GO:0035269///protein O-linked mannosylation+++GO:0071712///ER-associated misfolded protein catabolic process","protein O-mannosyltransferase 2","[POMT2_HUMAN|Reviewed]RecName: Full=Protein O-mannosyl-transferase 2; EC=2.4.1.109; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 2;+++[A0A0J9YVW4_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 2 {ECO:0000313|Ensembl:ENSP00000487704}; Flags: Fragment;+++[G3V4X9_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 2 {ECO:0000313|Ensembl:ENSP00000452060}; Flags: Fragment;+++[H0YJA9_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 2 {ECO:0000313|Ensembl:ENSP00000451115}; Flags: Fragment;+++[H0YJJ4_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 2 {ECO:0000313|Ensembl:ENSP00000451651}; Flags: Fragment;+++[H0YJK9_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 2 {ECO:0000313|Ensembl:ENSP00000451730}; Flags: Fragment;+++[H0YJQ7_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 2 {ECO:0000313|Ensembl:ENSP00000451967}; Flags: Fragment;"]
[29997,"'NOP53'",3241,3619,3061,3307,"05168///Herpes simplex infection",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular+++GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0033553///rDNA heterochromatin+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0008097///5S rRNA binding","GO:0071456///cellular response to hypoxia+++GO:1902570///protein localization to nucleolus+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0051726///regulation of cell cycle+++GO:0031333///negative regulation of protein complex assembly+++GO:1903006///positive regulation of protein K63-linked deubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0042254///ribosome biogenesis+++GO:0000027///ribosomal large subunit assembly+++GO:0006364///rRNA processing+++GO:0042981///regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0001932///regulation of protein phosphorylation+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0039535///regulation of RIG-I signaling pathway+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:0051898///negative regulation of protein kinase B signaling+++GO:1903715///regulation of aerobic respiration+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:1990173///protein localization to nucleoplasm","NOP53 ribosome biogenesis factor","[NOP53_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein NOP53 {ECO:0000305}; AltName: Full=Glioma tumor suppressor candidate region gene 2 protein {ECO:0000312|HGNC:HGNC:4333}; AltName: Full=Protein interacting with carboxyl terminus 1 {ECO:0000303|PubMed:15355975}; Short=PICT-1 {ECO:0000303|PubMed:15355975}; AltName: Full=p60 {ECO:0000303|PubMed:10196275};+++[M0QX73_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000468948}; Flags: Fragment;+++[M0QYZ9_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000470190}; Flags: Fragment;+++[M0QZ34_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000470263}; Flags: Fragment;+++[M0QZU5_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000470773}; Flags: Fragment;+++[Q96CS0_HUMAN|Unreviewed]SubName: Full=GLTSCR2 protein {ECO:0000313|EMBL:AAH14009.2}; Flags: Fragment;"]
[30000,"'TNPO2'",2355,2715,2445,2505,{"$nulls":4},"GO:0005623///cell+++GO:0034399///nuclear periphery+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane","GO:0008536///Ran GTPase binding+++GO:0008139///nuclear localization sequence binding+++GO:0005515///protein binding","GO:0006610///ribosomal protein import into nucleus+++GO:0006886///intracellular protein transport+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0006607///NLS-bearing protein import into nucleus","transportin 2","[TNPO2_HUMAN|Reviewed]RecName: Full=Transportin-2; AltName: Full=Karyopherin beta-2b;+++[A0A024R7F7_HUMAN|Unreviewed]SubName: Full=Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA_b {ECO:0000313|EMBL:EAW84301.1};+++[A0A075B780_HUMAN|Unreviewed]SubName: Full=Transportin-2 {ECO:0000313|Ensembl:ENSP00000468101};+++[K7ELC3_HUMAN|Unreviewed]SubName: Full=Transportin-2 {ECO:0000313|Ensembl:ENSP00000466011}; Flags: Fragment;+++[K7EMA3_HUMAN|Unreviewed]SubName: Full=Transportin-2 {ECO:0000313|Ensembl:ENSP00000466421}; Flags: Fragment;+++[K7ENW1_HUMAN|Unreviewed]SubName: Full=Transportin-2 {ECO:0000313|Ensembl:ENSP00000467115}; Flags: Fragment;+++[K7ESC1_HUMAN|Unreviewed]SubName: Full=Transportin-2 {ECO:0000313|Ensembl:ENSP00000468642};+++[K7ESG1_HUMAN|Unreviewed]SubName: Full=Transportin-2 {ECO:0000313|Ensembl:ENSP00000468698}; Flags: Fragment;+++[K7ESJ3_HUMAN|Unreviewed]SubName: Full=Transportin-2 {ECO:0000313|Ensembl:ENSP00000468739}; Flags: Fragment;+++[L8ECE4_HUMAN|Unreviewed]SubName: Full=Alternative protein TNPO2 {ECO:0000313|EMBL:CCQ43422.1};+++[Q05D48_HUMAN|Unreviewed]SubName: Full=TNPO2 protein {ECO:0000313|EMBL:AAH18314.1}; Flags: Fragment;+++[Q4LE60_HUMAN|Unreviewed]SubName: Full=TNPO2 variant protein {ECO:0000313|EMBL:BAE06093.1}; Flags: Fragment;"]
[3015,"'H2AFZ'",617,445,489,517,"05322///Systemic lupus erythematosus+++05034///Alcoholism+++04217///Necroptosis",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0001740///Barr body+++GO:0005720///nuclear heterochromatin+++GO:0005634///nucleus+++GO:0005719///nuclear euchromatin+++GO:0000790///nuclear chromatin+++GO:0000786///nucleosome+++GO:0005694///chromosome","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0031490///chromatin DNA binding+++GO:0005515///protein binding+++GO:0031492///nucleosomal DNA binding","GO:0006325///chromatin organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071392///cellular response to estradiol stimulus","H2A histone family member Z","[H2AZ_HUMAN|Reviewed]RecName: Full=Histone H2A.Z; Short=H2A/z;"]
[3053,"'SERPIND1'",3,1,4,2.66666666666667,"04610///Complement and coagulation cascades","H00223///Inherited thrombophilia","M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R03361///ATP:1-Phosphatidyl-1D-myo-inositol 4-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate","GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0070062///extracellular exosome","GO:0004866///endopeptidase inhibitor activity+++GO:0008201///heparin binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0006935///chemotaxis+++GO:0044267///cellular protein metabolic process+++GO:0010466///negative regulation of peptidase activity+++GO:0007596///blood coagulation+++GO:0010951///negative regulation of endopeptidase activity+++GO:0007599///hemostasis+++GO:0043687///post-translational protein modification","serpin family D member 1","[HEP2_HUMAN|Reviewed]RecName: Full=Heparin cofactor 2; AltName: Full=Heparin cofactor II; Short=HC-II; AltName: Full=Protease inhibitor leuserpin-2; Short=HLS2; AltName: Full=Serpin D1; Flags: Precursor;+++[Q8IVC0_HUMAN|Unreviewed]SubName: Full=Serpin peptidase inhibitor, clade D (Heparin cofactor), member 1 {ECO:0000313|EMBL:AAH35028.1};"]
[3074,"'HEXB'",2714,2236,2191,2380.33333333333,"01100///Metabolic pathways+++00513///Various types of N-glycan biosynthesis+++00531///Glycosaminoglycan degradation+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++04142///Lysosome+++00520///Amino sugar and nucleotide sugar metabolism+++00604///Glycosphingolipid biosynthesis - ganglio series+++00511///Other glycan degradation","H00124///GM2 gangliosidoses+++H02016///Tay-Sachs disease+++H00426///Defects in the degradation of ganglioside+++H02017///Sandhoff disease","M00079///Keratan sulfate degradation","R06004///GM2 + H2O <=> GM3 + N-Acetyl-D-galactosamine+++R11316///G13056 + H2O <=> N-Acetyl-D-glucosamine + G10665+++R00022///chitobiose N-acetylglucosaminohydrolase   Chitobiose + H2O <=> 2 N-Acetyl-D-glucosamine","GO:0001669///acrosomal vesicle+++GO:0005764///lysosome+++GO:0043202///lysosomal lumen+++GO:0042582///azurophil granule+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0035578///azurophil granule lumen+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0046982///protein heterodimerization activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0042803///protein homodimerization activity+++GO:0004563///beta-N-acetylhexosaminidase activity+++GO:0016787///hydrolase activity+++GO:0102148///N-acetyl-beta-D-galactosaminidase activity","GO:0042552///myelination+++GO:0007040///lysosome organization+++GO:0005975///carbohydrate metabolic process+++GO:0030207///chondroitin sulfate catabolic process+++GO:0007341///penetration of zona pellucida+++GO:0007338///single fertilization+++GO:0007605///sensory perception of sound+++GO:0050905///neuromuscular process+++GO:0006874///cellular calcium ion homeostasis+++GO:0042340///keratan sulfate catabolic process+++GO:0048477///oogenesis+++GO:0043312///neutrophil degranulation+++GO:0006687///glycosphingolipid metabolic process+++GO:0030214///hyaluronan catabolic process+++GO:0006689///ganglioside catabolic process+++GO:0007626///locomotory behavior+++GO:0008654///phospholipid biosynthetic process+++GO:0050885///neuromuscular process controlling balance+++GO:0008152///metabolic process+++GO:0008360///regulation of cell shape+++GO:0031323///regulation of cellular metabolic process+++GO:0008049///male courtship behavior+++GO:0030203///glycosaminoglycan metabolic process+++GO:0019953///sexual reproduction+++GO:0043615///astrocyte cell migration+++GO:0019915///lipid storage+++GO:0001501///skeletal system development+++GO:0044267///cellular protein metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0009313///oligosaccharide catabolic process","hexosaminidase subunit beta","[HEXB_HUMAN|Reviewed]RecName: Full=Beta-hexosaminidase subunit beta; EC=3.2.1.52; AltName: Full=Beta-N-acetylhexosaminidase subunit beta; Short=Hexosaminidase subunit B; AltName: Full=Cervical cancer proto-oncogene 7 protein; Short=HCC-7; AltName: Full=N-acetyl-beta-glucosaminidase subunit beta; Contains: RecName: Full=Beta-hexosaminidase subunit beta chain B; Contains: RecName: Full=Beta-hexosaminidase subunit beta chain A; Flags: Precursor;+++[A0A024RAJ6_HUMAN|Unreviewed]RecName: Full=Beta-hexosaminidase {ECO:0000256|PIRNR:PIRNR001093}; EC=3.2.1.52 {ECO:0000256|PIRNR:PIRNR001093};+++[D6REQ8_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000424939};+++[H0Y9B6_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000423713}; Flags: Fragment;+++[H0Y9M3_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000424550}; Flags: Fragment;+++[H0YA83_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000426384}; Flags: Fragment;+++[Q5URX0_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000426285}; SubName: Full=ENC-1AS {ECO:0000313|EMBL:AAV48875.1}; SubName: Full=Epididymis luminal protein 248 {ECO:0000313|EMBL:ACI46028.1}; SubName: Full=Epididymis secretory protein Li 111 {ECO:0000313|EMBL:ACV87197.1};"]
[3083,"'HGFAC'",4,3,5,4,{"$nulls":4},"GO:0005791///rough endoplasmic reticulum+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0008236///serine-type peptidase activity+++GO:0004252///serine-type endopeptidase activity","GO:0006508///proteolysis","HGF activator","[HGFA_HUMAN|Reviewed]RecName: Full=Hepatocyte growth factor activator; Short=HGF activator; Short=HGFA; EC=3.4.21.-; Contains: RecName: Full=Hepatocyte growth factor activator short chain; Contains: RecName: Full=Hepatocyte growth factor activator long chain; Flags: Precursor;+++[D6RAR4_HUMAN|Unreviewed]SubName: Full=Hepatocyte growth factor activator {ECO:0000313|Ensembl:ENSP00000421801};"]
[3092,"'HIP1'",442,406.49,402.7,417.063333333333,"05016///Huntington's disease",{"$nulls":3},"GO:0030122///AP-2 adaptor complex+++GO:0016020///membrane+++GO:0030479///actin cortical patch+++GO:0005794///Golgi apparatus+++GO:0030665///clathrin-coated vesicle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0005634///nucleus+++GO:0098888///extrinsic component of presynaptic membrane+++GO:0005737///cytoplasm+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0031410///cytoplasmic vesicle+++GO:0005856///cytoskeleton+++GO:0030136///clathrin-coated vesicle+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane","GO:0003779///actin binding+++GO:0035091///phosphatidylinositol binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0035615///clathrin adaptor activity+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0032051///clathrin light chain binding+++GO:0035254///glutamate receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0005543///phospholipid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0051015///actin filament binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0030276///clathrin binding","GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0042981///regulation of apoptotic process+++GO:0072583///clathrin-dependent endocytosis+++GO:0006915///apoptotic process+++GO:0097190///apoptotic signaling pathway+++GO:2000588///positive regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0099637///neurotransmitter receptor transport+++GO:0030154///cell differentiation+++GO:0030100///regulation of endocytosis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0050821///protein stabilization+++GO:0048268///clathrin coat assembly+++GO:0061024///membrane organization+++GO:0007015///actin filament organization+++GO:0006897///endocytosis+++GO:0051897///positive regulation of protein kinase B signaling","huntingtin interacting protein 1","[HIP1_HUMAN|Reviewed]RecName: Full=Huntingtin-interacting protein 1; Short=HIP-1; AltName: Full=Huntingtin-interacting protein I; Short=HIP-I;+++[A0A0A6ZH24_HUMAN|Unreviewed]SubName: Full=HCG1795174 {ECO:0000313|EMBL:EAW71769.1}; SubName: Full=SHONbeta {ECO:0000313|EMBL:AGS49178.1};+++[A0A0A6ZH34_HUMAN|Unreviewed]SubName: Full=SHONgamma {ECO:0000313|EMBL:AGS49179.1};+++[A4VCI6_HUMAN|Unreviewed]SubName: Full=HIP1 protein {ECO:0000313|EMBL:AAI39787.1}; Flags: Fragment;+++[B4DK46_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56785, highly similar to Huntingtin-interacting protein 1 {ECO:0000313|EMBL:BAG59058.1};+++[C9JMG5_HUMAN|Unreviewed]SubName: Full=Huntingtin-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000414280}; Flags: Fragment;+++[Q6UY29_HUMAN|Unreviewed]SubName: Full=PIKR2786 {ECO:0000313|EMBL:AAQ88470.1}; SubName: Full=SHONalpha {ECO:0000313|EMBL:AGS49177.1};+++[Q8TDA4_HUMAN|Unreviewed]SubName: Full=Huntingtin-interacting protein 1 {ECO:0000313|EMBL:AAL93198.1}; Flags: Fragment;"]
[3109,"'HLA-DMB'",0,1,0,0.333333333333333,"04145///Phagosome+++05323///Rheumatoid arthritis+++04612///Antigen processing and presentation+++05310///Asthma+++05320///Autoimmune thyroid disease+++05145///Toxoplasmosis+++05152///Tuberculosis+++05332///Graft-versus-host disease+++05321///Inflammatory bowel disease (IBD)+++05140///Leishmaniasis+++05416///Viral myocarditis+++04640///Hematopoietic cell lineage+++05168///Herpes simplex infection+++04514///Cell adhesion molecules (CAMs)+++05322///Systemic lupus erythematosus+++05164///Influenza A+++05330///Allograft rejection+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05166///HTLV-I infection+++05150///Staphylococcus aureus infection+++04940///Type I diabetes mellitus+++04672///Intestinal immune network for IgA production","H00295///Viral myocarditis+++H00081///Hashimoto's thyroiditis+++H01504///Vogt-Koyanagi-Harada syndrome+++H00079///Asthma+++H00080///Systemic lupus erythematosus+++H00294///Dilated cardiomyopathy (DCM)+++H01516///Adult onset Still's disease+++H01468///Eosinophilic granulomatosis with polyangiitis+++H02123///Celiac disease+++H01502///Sjogren's syndrome+++H01490///Multiple sclerosis+++H00082///Graves' disease+++H00342///Tuberculosis+++H00083///Allograft rejection+++H00408///Type I diabetes mellitus+++H01362///Dermatitis herpetiformis+++H01492///Systemic sclerosis+++H01698///Giant cell arteritis",null,null,"GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0042613///MHC class II protein complex+++GO:0005768///endosome","GO:0005515///protein binding+++GO:0023026///MHC class II protein complex binding","GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0019882///antigen processing and presentation+++GO:0042102///positive regulation of T cell proliferation+++GO:0002503///peptide antigen assembly with MHC class II protein complex+++GO:0006955///immune response+++GO:0002376///immune system process+++GO:0002399///MHC class II protein complex assembly+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:2001190///positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell","major histocompatibility complex, class II, DM beta","[DMB_HUMAN|Reviewed]RecName: Full=HLA class II histocompatibility antigen, DM beta chain; AltName: Full=MHC class II antigen DMB; AltName: Full=Really interesting new gene 7 protein; Flags: Precursor;+++[A0A0G2JI43_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000394997};+++[A0A0G2JIJ2_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000399130};+++[A0A140T926_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000389736}; Flags: Fragment;+++[A0A140T943_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000391352}; Flags: Fragment;+++[A0A140T946_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000391679}; Flags: Fragment;+++[A0A140T965_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000393285}; Flags: Fragment;+++[A0A140T987_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000394737}; Flags: Fragment;+++[A0A140T9B6_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000398332}; Flags: Fragment;+++[A0A140T9C6_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000399634}; Flags: Fragment;+++[A0A140T9C9_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000398843}; Flags: Fragment;+++[A0A140T9E3_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000399759}; Flags: Fragment;+++[A0A140T9F5_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000401238}; Flags: Fragment;+++[A0A140T9F6_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000401587}; Flags: Fragment;+++[A0A140T9I2_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000404072}; Flags: Fragment;+++[A0A140T9K0_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000405790}; Flags: Fragment;+++[A0A140T9K4_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000405746}; Flags: Fragment;+++[A0A140T9K9_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000406776}; Flags: Fragment;+++[A0A140T9Q5_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000410077}; Flags: Fragment;+++[A0A140T9Q8_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000410609}; Flags: Fragment;+++[A0A140T9R0_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000410329}; Flags: Fragment;+++[A0A140T9R2_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000410908}; Flags: Fragment;+++[A0A140T9T8_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000412415}; Flags: Fragment;+++[A0A140T9U6_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000414153}; Flags: Fragment;+++[A0A1V0E3K4_HUMAN|Unreviewed]SubName: Full=HLA-DMB {ECO:0000313|EMBL:ARB08364.1};+++[A0A1V0E3L6_HUMAN|Unreviewed]SubName: Full=HLA-DMB {ECO:0000313|EMBL:ARB08382.1};+++[A0A1V0E3N8_HUMAN|Unreviewed]SubName: Full=HLA-DMB {ECO:0000313|EMBL:ARB08379.1};+++[A0A1V0E3P2_HUMAN|Unreviewed]SubName: Full=HLA-DMB {ECO:0000313|EMBL:ARB08377.1};+++[A8CGH7_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:BAF81534.1}; Flags: Fragment;+++[A8CGH8_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:BAF81535.1}; Flags: Fragment;+++[A8CGH9_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:BAF81536.1}; Flags: Fragment;+++[H0Y4B8_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000390848}; Flags: Fragment;+++[H0Y7A2_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DM beta chain {ECO:0000313|Ensembl:ENSP00000411276}; Flags: Fragment;+++[O02952_HUMAN|Unreviewed]SubName: Full=MHC class II HLA-DMB {ECO:0000313|EMBL:AAB61609.1}; Flags: Fragment;+++[Q29709_HUMAN|Unreviewed]SubName: Full=MHC class II antigen HLA-DM beta chain {ECO:0000313|EMBL:AAC50517.1}; Flags: Fragment;+++[Q52RG1_HUMAN|Unreviewed]SubName: Full=MHC class II antigen beta chain {ECO:0000313|EMBL:AAX84974.1}; Flags: Fragment;+++[Q6LEU6_HUMAN|Unreviewed]SubName: Full=HLA-DMB protein {ECO:0000313|EMBL:CAG28534.1}; Flags: Fragment;+++[X5CKA5_HUMAN|Unreviewed]SubName: Full=HLA-DMB {ECO:0000313|EMBL:ARB08365.1}; SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AHW47928.1};"]
[3145,"'HMBS'",232,244,235,237,"01100///Metabolic pathways+++00860///Porphyrin and chlorophyll metabolism+++01110///Biosynthesis of secondary metabolites+++01120///Microbial metabolism in diverse environments","H00202///Hepatic porphyria+++H01763///Porphyria","M00846///Siroheme biosynthesis, glutamate => siroheme+++M00121///Heme biosynthesis, glutamate => heme","R00084///porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing); porphobilinogen   4 Porphobilinogen + H2O <=> Hydroxymethylbilane + 4 Ammonia","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0004418///hydroxymethylbilane synthase activity+++GO:0016740///transferase activity","GO:0018160///peptidyl-pyrromethane cofactor linkage+++GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0033014///tetrapyrrole biosynthetic process+++GO:0006779///porphyrin-containing compound biosynthetic process","hydroxymethylbilane synthase","[HEM3_HUMAN|Reviewed]RecName: Full=Porphobilinogen deaminase; Short=PBG-D; EC=2.5.1.61; AltName: Full=Hydroxymethylbilane synthase; Short=HMBS; AltName: Full=Pre-uroporphyrinogen synthase;+++[A0A1W2PNU5_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000491061};+++[B5U9V4_HUMAN|Unreviewed]SubName: Full=Hydroxymethylbilane synthase {ECO:0000313|EMBL:BAG71787.1}; Flags: Fragment;+++[F1DBF3_HUMAN|Unreviewed]SubName: Full=Hydroxymethylbilane synthase {ECO:0000313|EMBL:ADX60069.1}; EC=2.5.1.61 {ECO:0000313|EMBL:ADX60069.1}; Flags: Fragment;+++[F5GY90_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000440092}; Flags: Fragment;+++[F5H0P4_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000438726}; Flags: Fragment;+++[F5H226_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000445599}; Flags: Fragment;+++[F5H345_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000445429};+++[F5H4W5_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000439904};+++[F5H4X2_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000444849};+++[F5H4Y7_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|Ensembl:ENSP00000444817};+++[Q0G847_HUMAN|Unreviewed]SubName: Full=Hydroxymethylbilane synthase {ECO:0000313|EMBL:ABI36594.1}; Flags: Fragment;+++[Q68Y91_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|EMBL:BAD36778.1}; Flags: Fragment;+++[V9GZN3_HUMAN|Unreviewed]SubName: Full=Porphobilinogen deaminase {ECO:0000313|EMBL:AAA60028.1}; EC=2.5.1.61 {ECO:0000313|EMBL:AAA60028.1}; Flags: Fragment;+++[X5FSX0_HUMAN|Unreviewed]SubName: Full=Hydroxymethylbilane synthase {ECO:0000313|EMBL:AHW82961.1}; Flags: Fragment;"]
[3164,"'NR4A1'",172,152,134,152.666666666667,"04010///MAPK signaling pathway+++04934///Cushing's syndrome+++04925///Aldosterone synthesis and secretion+++04927///Cortisol synthesis and secretion+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005634///nucleus","GO:0042803///protein homodimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003707///steroid hormone receptor activity+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0035259///glucocorticoid receptor binding+++GO:0008270///zinc ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004879///nuclear receptor activity+++GO:0008134///transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0030522///intracellular receptor signaling pathway+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0035767///endothelial cell chemotaxis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0045444///fat cell differentiation+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0006915///apoptotic process+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0071310///cellular response to organic substance+++GO:0045786///negative regulation of cell cycle+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035914///skeletal muscle cell differentiation+++GO:0007165///signal transduction+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process","nuclear receptor subfamily 4 group A member 1","[NR4A1_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 4 group A member 1; AltName: Full=Early response protein NAK1; AltName: Full=Nuclear hormone receptor NUR/77; Short=Nur77; AltName: Full=Orphan nuclear receptor HMR; AltName: Full=Orphan nuclear receptor TR3; AltName: Full=ST-59; AltName: Full=Testicular receptor 3;+++[A0A024R126_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4, group A, member 1, isoform CRA_d {ECO:0000313|EMBL:EAW58226.1};+++[F5GXF0_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|Ensembl:ENSP00000440864};+++[F8VVX9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|Ensembl:ENSP00000449858}; Flags: Fragment;+++[H3BPN8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|Ensembl:ENSP00000455399}; Flags: Fragment;+++[H3BQG5_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|Ensembl:ENSP00000455767}; Flags: Fragment;+++[H3BSB9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|Ensembl:ENSP00000456633}; Flags: Fragment;+++[H3BSM8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|Ensembl:ENSP00000456776}; Flags: Fragment;+++[H3BT85_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 1 {ECO:0000313|Ensembl:ENSP00000457070}; Flags: Fragment;+++[Q6ZMM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16818 fis, clone TRACH1000193, highly similar to Orphan nuclear receptor HMR {ECO:0000313|EMBL:BAD18699.1};"]
[3181,"'HNRNPA2B1'",3032,3076,2921,3009.66666666667,null,"H02031///Inclusion body myopathy with Paget disease of bone and frontotemporal dementia",null,null,"GO:0016363///nuclear matrix+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005623///cell+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm","GO:0003730///mRNA 3'-UTR binding+++GO:0097157///pre-mRNA intronic binding+++GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0035198///miRNA binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:1990247///N6-methyladenosine-containing RNA binding","GO:0031053///primary miRNA processing+++GO:0016070///RNA metabolic process+++GO:0044806///G-quadruplex DNA unwinding+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008380///RNA splicing+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0051028///mRNA transport+++GO:1905663///positive regulation of telomerase RNA reverse transcriptase activity+++GO:0050658///RNA transport+++GO:0006397///mRNA processing+++GO:1990428///miRNA transport+++GO:0006406///mRNA export from nucleus+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0000398///mRNA splicing, via spliceosome","heterogeneous nuclear ribonucleoprotein A2/B1","[ROA2_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoproteins A2/B1; Short=hnRNP A2/B1;+++[A0A024RA28_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A2/B1, isoform CRA_d {ECO:0000313|EMBL:EAW93841.1};+++[A0A087WUI2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoproteins A2/B1 {ECO:0000313|Ensembl:ENSP00000478691};+++[I6L957_HUMAN|Unreviewed]SubName: Full=HNRNPA2B1 protein {ECO:0000313|EMBL:AAH00506.3};"]
[3204,"'HOXA7'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0031965///nuclear membrane+++GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding","GO:0045617///negative regulation of keratinocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001525///angiogenesis+++GO:0002686///negative regulation of leukocyte migration+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0045656///negative regulation of monocyte differentiation+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0048863///stem cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0009952///anterior/posterior pattern specification+++GO:0007275///multicellular organism development","homeobox A7","[HXA7_HUMAN|Reviewed]RecName: Full=Homeobox protein Hox-A7; AltName: Full=Homeobox protein Hox 1.1; AltName: Full=Homeobox protein Hox-1A;+++[E5RHM9_HUMAN|Unreviewed]SubName: Full=Homeobox protein Hox-A7 {ECO:0000313|Ensembl:ENSP00000428563}; Flags: Fragment;"]
[326340,"'ZAR1'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005737///cytoplasm",null,"GO:0007275///multicellular organism development","zygote arrest 1","[ZAR1_HUMAN|Reviewed]RecName: Full=Zygote arrest protein 1; AltName: Full=Oocyte-specific maternal effect factor;+++[B9EG67_HUMAN|Unreviewed]SubName: Full=Zygote arrest 1 {ECO:0000313|EMBL:AAI36266.1};"]
[328,"'APEX1'",3922,3824,3769,3838.33333333333,"03410///Base excision repair",null,"M00296///BER complex",null,"GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0016234///inclusion body+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005856///cytoskeleton+++GO:0032839///dendrite cytoplasm+++GO:0016607///nuclear speck+++GO:0030424///axon+++GO:1904115///axon cytoplasm+++GO:0005764///lysosome+++GO:0005840///ribosome+++GO:0005783///endoplasmic reticulum+++GO:0042995///cell projection+++GO:0015629///actin cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0005813///centrosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm+++GO:0045202///synapse+++GO:0005730///nucleolus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005814///centriole+++GO:0008021///synaptic vesicle+++GO:0005739///mitochondrion+++GO:0005776///autophagosome","GO:0016890///site-specific endodeoxyribonuclease activity, specific for altered base+++GO:0004844///uracil DNA N-glycosylase activity+++GO:0005102///signaling receptor binding+++GO:0004519///endonuclease activity+++GO:0003677///DNA binding+++GO:0004520///endodeoxyribonuclease activity+++GO:0003714///transcription corepressor activity+++GO:0048403///brain-derived neurotrophic factor binding+++GO:0051059///NF-kappaB binding+++GO:0003713///transcription coactivator activity+++GO:0016829///lyase activity+++GO:0003691///double-stranded telomeric DNA binding+++GO:0044325///ion channel binding+++GO:0004527///exonuclease activity+++GO:0016491///oxidoreductase activity+++GO:0017022///myosin binding+++GO:0003684///damaged DNA binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0003723///RNA binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004518///nuclease activity+++GO:0004528///phosphodiesterase I activity+++GO:0008311///double-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0005515///protein binding+++GO:0008309///double-stranded DNA exodeoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0044877///protein-containing complex binding","GO:0098957///anterograde axonal transport of mitochondrion+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0021549///cerebellum development+++GO:0048311///mitochondrion distribution+++GO:0070301///cellular response to hydrogen peroxide+++GO:0006281///DNA repair+++GO:0042981///regulation of apoptotic process+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0017157///regulation of exocytosis+++GO:0008090///retrograde axonal transport+++GO:0042493///response to drug+++GO:0008104///protein localization+++GO:0055114///oxidation-reduction process+++GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0006605///protein targeting+++GO:0080111///DNA demethylation+++GO:0007568///aging+++GO:0007268///chemical synaptic transmission+++GO:0032901///positive regulation of neurotrophin production+++GO:0007420///brain development+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0006310///DNA recombination+++GO:0021979///hypothalamus cell differentiation+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:0030030///cell projection organization+++GO:0071320///cellular response to cAMP+++GO:0071417///cellular response to organonitrogen compound+++GO:0050769///positive regulation of neurogenesis+++GO:1902430///negative regulation of amyloid-beta formation+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0010243///response to organonitrogen compound+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0047496///vesicle transport along microtubule+++GO:0008089///anterograde axonal transport+++GO:0006284///base-excision repair+++GO:0031587///positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0045454///cell redox homeostasis+++GO:0000723///telomere maintenance+++GO:0097698///telomere maintenance via base-excision repair+++GO:0006914///autophagy+++GO:0022008///neurogenesis+++GO:0006286///base-excision repair, base-free sugar-phosphate removal+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043488///regulation of mRNA stability+++GO:1902513///regulation of organelle transport along microtubule","apurinic/apyrimidinic endodeoxyribonuclease 1","[APEX1_HUMAN|Reviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase; EC=3.1.-.-; EC=4.2.99.18; AltName: Full=APEX nuclease; Short=APEN; AltName: Full=Apurinic-apyrimidinic endonuclease 1; Short=AP endonuclease 1; Short=APE-1; AltName: Full=REF-1; AltName: Full=Redox factor-1; Contains: RecName: Full=DNA-(apurinic or apyrimidinic site) lyase, mitochondrial;+++[A0A0C4DGK8_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131}; Flags: Fragment;+++[A0A2S1WCK0_HUMAN|Unreviewed]SubName: Full=APE1 {ECO:0000313|EMBL:AWJ64391.1}; Flags: Fragment;+++[A0A2S1WCK3_HUMAN|Unreviewed]SubName: Full=APE1 {ECO:0000313|EMBL:AWJ64392.1}; Flags: Fragment;+++[G3V2D9_HUMAN|Unreviewed]SubName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000313|Ensembl:ENSP00000450604};+++[G3V359_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131}; Flags: Fragment;+++[G3V3C7_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131}; Flags: Fragment;+++[G3V3M6_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131}; Flags: Fragment;+++[G3V3Y6_HUMAN|Unreviewed]SubName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000313|Ensembl:ENSP00000451491}; Flags: Fragment;+++[G3V574_HUMAN|Unreviewed]SubName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000313|Ensembl:ENSP00000452212};+++[G3V5D9_HUMAN|Unreviewed]SubName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000313|Ensembl:ENSP00000452304}; Flags: Fragment;+++[G3V5M0_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131}; Flags: Fragment;+++[G3V5Q1_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131}; Flags: Fragment;+++[H7C4A8_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131}; Flags: Fragment;+++[Q5TZP7_HUMAN|Unreviewed]RecName: Full=DNA-(apurinic or apyrimidinic site) lyase {ECO:0000256|RuleBase:RU362131}; EC=4.2.99.18 {ECO:0000256|RuleBase:RU362131};"]
[3300,"'DNAJB2'",1106,1055,1013,1058,"04141///Protein processing in endoplasmic reticulum","H00856///Distal hereditary motor neuropathies (dHMN)",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0042406///extrinsic component of endoplasmic reticulum membrane+++GO:0016234///inclusion body+++GO:0098554///cytoplasmic side of endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0000502///proteasome complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0031227///intrinsic component of endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0001671///ATPase activator activity+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0051087///chaperone binding+++GO:0043130///ubiquitin binding+++GO:0030544///Hsp70 protein binding+++GO:0051082///unfolded protein binding+++GO:0140036///ubiquitin-dependent protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0070628///proteasome binding","GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0090084///negative regulation of inclusion body assembly+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0031396///regulation of protein ubiquitination+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0090086///negative regulation of protein deubiquitination+++GO:0006986///response to unfolded protein+++GO:0030308///negative regulation of cell growth+++GO:1903644///regulation of chaperone-mediated protein folding+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032091///negative regulation of protein binding+++GO:0042026///protein refolding+++GO:0070050///neuron cellular homeostasis+++GO:0061077///chaperone-mediated protein folding+++GO:0032781///positive regulation of ATPase activity+++GO:0032880///regulation of protein localization","DnaJ heat shock protein family (Hsp40) member B2","[DNJB2_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily B member 2 {ECO:0000305}; AltName: Full=Heat shock 40 kDa protein 3 {ECO:0000312|MIM:604139}; AltName: Full=Heat shock protein J1 {ECO:0000303|PubMed:1599432}; Short=HSJ-1 {ECO:0000303|PubMed:1599432}; Flags: Precursor;+++[C9J1G2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 2 {ECO:0000313|Ensembl:ENSP00000392790}; Flags: Fragment;+++[C9JRD2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 2 {ECO:0000313|Ensembl:ENSP00000414796}; Flags: Fragment;+++[C9JX00_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 2 {ECO:0000313|Ensembl:ENSP00000387951}; Flags: Fragment;+++[C9JXB9_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 2 {ECO:0000313|Ensembl:ENSP00000375937}; Flags: Fragment;+++[E7ETU0_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 2 {ECO:0000313|Ensembl:ENSP00000395173}; Flags: Fragment;"]
[3337,"'DNAJB1'",2490,2342,2241,2357.66666666667,"05164///Influenza A+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0061827///sperm head+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0098978///glutamatergic synapse+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0098794///postsynapse+++GO:0014069///postsynaptic density+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0001671///ATPase activator activity+++GO:0051087///chaperone binding+++GO:0003714///transcription corepressor activity+++GO:0030544///Hsp70 protein binding+++GO:0045296///cadherin binding+++GO:0051082///unfolded protein binding+++GO:0051117///ATPase binding","GO:0090084///negative regulation of inclusion body assembly+++GO:1900034///regulation of cellular response to heat+++GO:0006457///protein folding+++GO:0006986///response to unfolded protein+++GO:0030900///forebrain development+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032781///positive regulation of ATPase activity","DnaJ heat shock protein family (Hsp40) member B1","[DNJB1_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily B member 1; AltName: Full=DnaJ protein homolog 1; AltName: Full=Heat shock 40 kDa protein 1; Short=HSP40; Short=Heat shock protein 40; AltName: Full=Human DnaJ protein 1; Short=hDj-1;+++[A0A1B0GX60_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000472886}; Flags: Fragment;+++[M0QXK0_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000469221}; Flags: Fragment;+++[M0QYT3_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000470063}; Flags: Fragment;+++[M0QZD0_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000470460}; Flags: Fragment;+++[M0R080_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000471073}; Flags: Fragment;+++[M0R128_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000471603}; Flags: Fragment;+++[M0R1D6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000471798}; Flags: Fragment;+++[Q6FHS4_HUMAN|Unreviewed]SubName: Full=DNAJB1 protein {ECO:0000313|EMBL:CAG46478.1}; SubName: Full=DnaJ (Hsp40) homolog, subfamily B, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW84432.1}; SubName: Full=cDNA, FLJ93008, Homo sapiens DnaJ (Hsp40) homolog, subfamily B, member 1 (DNAJB1),mRNA {ECO:0000313|EMBL:BAG35510.1}; Flags: Fragment;+++[Q6FI51_HUMAN|Unreviewed]SubName: Full=DNAJB1 protein {ECO:0000313|EMBL:CAG38724.1};"]
[3352,"'HTR1D'",27,26,18,23.6666666666667,"04742///Taste transduction+++04080///Neuroactive ligand-receptor interaction+++04024///cAMP signaling pathway+++04726///Serotonergic synapse","H01703///Eating Disorders",null,null,"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0030425///dendrite+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0006939///smooth muscle contraction+++GO:0050795///regulation of behavior+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0042310///vasoconstriction+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0014827///intestine smooth muscle contraction+++GO:0007165///signal transduction+++GO:0040012///regulation of locomotion+++GO:0098664///G protein-coupled serotonin receptor signaling pathway","5-hydroxytryptamine receptor 1D","[5HT1D_HUMAN|Reviewed]RecName: Full=5-hydroxytryptamine receptor 1D; Short=5-HT-1D; Short=5-HT1D; AltName: Full=Serotonin 1D alpha receptor; Short=5-HT-1D-alpha; AltName: Full=Serotonin receptor 1D;"]
[338324,"'S100A7A'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0046914///transition metal ion binding+++GO:0005509///calcium ion binding+++GO:0043621///protein self-association",null,"S100 calcium binding protein A7A","[S1A7A_HUMAN|Reviewed]RecName: Full=Protein S100-A7A; AltName: Full=S100 calcium-binding protein A15; AltName: Full=S100 calcium-binding protein A7-like 1; AltName: Full=S100 calcium-binding protein A7A;"]
[338692,"'ANKRD13D'",751,783,689,741,"04810///Regulation of actin cytoskeleton+++04360///Axon guidance",{"$nulls":3},"GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005768///endosome","GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0003779///actin binding","GO:0008064///regulation of actin polymerization or depolymerization+++GO:0010591///regulation of lamellipodium assembly+++GO:0050770///regulation of axonogenesis","ankyrin repeat domain 13D","[AN13D_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 13D;+++[A0A024R5D5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain 13 family, member D, isoform CRA_b {ECO:0000313|EMBL:EAW74585.1};+++[A0A087WWH4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 13D {ECO:0000313|Ensembl:ENSP00000480227}; Flags: Fragment;+++[A0A087WYW0_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 13D {ECO:0000313|Ensembl:ENSP00000482134}; Flags: Fragment;"]
[339230,"'CCDC137'",568,502,476,515.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005694///chromosome+++GO:0001650///fibrillar center+++GO:0005730///nucleolus","GO:0003723///RNA binding+++GO:0005515///protein binding",null,"coiled-coil domain containing 137","[CC137_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 137;+++[I3L0U5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 137 {ECO:0000313|Ensembl:ENSP00000458350}; Flags: Fragment;+++[I3L385_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 137 {ECO:0000313|Ensembl:ENSP00000460261}; Flags: Fragment;+++[I3L4F6_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 137 {ECO:0000313|Ensembl:ENSP00000461207}; Flags: Fragment;"]
[339366,"'ADAMTSL5'",989,1033,946,989.333333333333,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0001527///microfibril","GO:0008201///heparin binding+++GO:0005515///protein binding",null,"ADAMTS like 5","[ATL5_HUMAN|Reviewed]RecName: Full=ADAMTS-like protein 5; Short=ADAMTSL-5; AltName: Full=Thrombospondin type-1 domain-containing protein 6; Flags: Precursor;+++[A0A087WVY8_HUMAN|Unreviewed]SubName: Full=ADAMTS-like protein 5 {ECO:0000313|Ensembl:ENSP00000479786}; Flags: Fragment;+++[A0A087WZI4_HUMAN|Unreviewed]SubName: Full=ADAMTS-like protein 5 {ECO:0000313|Ensembl:ENSP00000482683}; Flags: Fragment;+++[A0A087X1N9_HUMAN|Unreviewed]SubName: Full=ADAMTS-like protein 5 {ECO:0000313|Ensembl:ENSP00000484344}; Flags: Fragment;+++[A4QPG6_HUMAN|Unreviewed]SubName: Full=ADAMTSL5 protein {ECO:0000313|EMBL:AAI39834.1};+++[K7ELV0_HUMAN|Unreviewed]SubName: Full=ADAMTS-like protein 5 {ECO:0000313|Ensembl:ENSP00000466231}; Flags: Fragment;+++[Q0VD77_HUMAN|Unreviewed]SubName: Full=ADAMTS-like protein 5 {ECO:0000313|Ensembl:ENSP00000378850}; SubName: Full=ADAMTSL5 protein {ECO:0000313|EMBL:AAI19797.1};+++[X6R4H8_HUMAN|Unreviewed]SubName: Full=ADAMTS-like protein 5 {ECO:0000313|Ensembl:ENSP00000327608};"]
[339834,"'CCDC36'",5,10,12,9,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome","GO:0005515///protein binding","GO:0007283///spermatogenesis+++GO:0007129///synapsis+++GO:0042138///meiotic DNA double-strand break formation+++GO:0051321///meiotic cell cycle+++GO:0030154///cell differentiation+++GO:0060629///regulation of homologous chromosome segregation+++GO:0048477///oogenesis+++GO:0006310///DNA recombination","coiled-coil domain containing 36","[IHO1_HUMAN|Reviewed]RecName: Full=Interactor of HORMAD1 protein 1 {ECO:0000303|PubMed:27723721}; AltName: Full=Cancer/testis antigen 74; Short=CT74; AltName: Full=Coiled-coil domain-containing protein 36 {ECO:0000312|HGNC:HGNC:27945};+++[B4DZP6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54644 {ECO:0000313|EMBL:BAG64158.1};"]
[3400,"'ID4'",181,144,118,147.666666666667,"04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0001085///RNA polymerase II transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046983///protein dimerization activity+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051726///regulation of cell cycle+++GO:0045444///fat cell differentiation+++GO:0061682///seminal vesicle morphogenesis+++GO:0048712///negative regulation of astrocyte differentiation+++GO:0060741///prostate gland stromal morphogenesis+++GO:0007405///neuroblast proliferation+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0030182///neuron differentiation+++GO:0034613///cellular protein localization+++GO:0045665///negative regulation of neuron differentiation+++GO:0021766///hippocampus development+++GO:0008284///positive regulation of cell proliferation+++GO:0007623///circadian rhythm+++GO:0060512///prostate gland morphogenesis+++GO:0022010///central nervous system myelination+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007420///brain development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045599///negative regulation of fat cell differentiation+++GO:0021895///cerebral cortex neuron differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0043392///negative regulation of DNA binding+++GO:0008283///cell proliferation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0010628///positive regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated","inhibitor of DNA binding 4, HLH protein","[ID4_HUMAN|Reviewed]RecName: Full=DNA-binding protein inhibitor ID-4; AltName: Full=Class B basic helix-loop-helix protein 27; Short=bHLHb27; AltName: Full=Inhibitor of DNA binding 4; AltName: Full=Inhibitor of differentiation 4;"]
[340527,"'NHSL2'",23,45,48,38.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004984///olfactory receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0030154///cell differentiation","NHS like 2","[NHSL2_HUMAN|Reviewed]RecName: Full=NHS-like protein 2;+++[A0A0J9YW69_HUMAN|Unreviewed]SubName: Full=NHS-like protein 2 {ECO:0000313|Ensembl:ENSP00000487835}; Flags: Fragment;+++[A0A0J9YY34_HUMAN|Unreviewed]SubName: Full=NHS-like protein 2 {ECO:0000313|Ensembl:ENSP00000488668};+++[A0A0J9YY72_HUMAN|Unreviewed]SubName: Full=NHS-like protein 2 {ECO:0000313|Ensembl:ENSP00000488715};+++[A0A1W2PQQ1_HUMAN|Unreviewed]SubName: Full=NHS-like protein 2 {ECO:0000313|Ensembl:ENSP00000492082};"]
[341019,"'DCDC1'",18,28,18,21.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0030496///midbody+++GO:1990904///ribonucleoprotein complex+++GO:0005874///microtubule+++GO:0005622///intracellular+++GO:0010494///cytoplasmic stress granule+++GO:0072686///mitotic spindle+++GO:0090543///Flemming body+++GO:0005737///cytoplasm","GO:0003697///single-stranded DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0042802///identical protein binding+++GO:0008017///microtubule binding+++GO:0000166///nucleotide binding","GO:0035556///intracellular signal transduction","doublecortin domain containing 1","[DCDC1_HUMAN|Reviewed]RecName: Full=Doublecortin domain-containing protein 1;+++[B6ZDN3_HUMAN|Unreviewed]SubName: Full=Doublecortin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000385936};+++[H0Y2Q8_HUMAN|Unreviewed]SubName: Full=Doublecortin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000306898}; Flags: Fragment;+++[H7C298_HUMAN|Unreviewed]SubName: Full=Doublecortin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000404672}; Flags: Fragment;+++[M0R2J8_HUMAN|Unreviewed]SubName: Full=Doublecortin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472625};"]
[341883,"'LRRC9'",0,0,1,0.333333333333333,{"$nulls":7},"leucine rich repeat containing 9","[LRRC9_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 9;+++[A0A2R8Y4H4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 9 {ECO:0000313|Ensembl:ENSP00000493790};+++[A0A2R8YDI6_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 9 {ECO:0000313|Ensembl:ENSP00000494624}; Flags: Fragment;+++[H3BUB1_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 9 {ECO:0000313|Ensembl:ENSP00000457559}; Flags: Fragment;+++[H3BUS4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 9 {ECO:0000313|Ensembl:ENSP00000457773}; Flags: Fragment;"]
[342850,"'ANKRD62'",1,0.99,1,0.996666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated","ankyrin repeat domain 62","[ANR62_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 62;+++[L0R816_HUMAN|Unreviewed]SubName: Full=Alternative protein ANKRD62 {ECO:0000313|EMBL:CCO13676.1};"]
[342979,"'PALM3'",0,1,2,1,"04060///Cytokine-cytokine receptor interaction+++04630///Jak-STAT signaling pathway+++04659///Th17 cell differentiation",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0032496///response to lipopolysaccharide+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0008063///Toll signaling pathway","paralemmin 3","[PALM3_HUMAN|Reviewed]RecName: Full=Paralemmin-3; Flags: Precursor;+++[K7EKN5_HUMAN|Unreviewed]SubName: Full=Paralemmin-3 {ECO:0000313|Ensembl:ENSP00000465701}; Flags: Fragment;"]
[344167,"'FOXI3'",4,4,2,3.33333333333333,null,"H00251///Thyroid dyshormonogenesis",null,null,"GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0009653///anatomical structure morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II","forkhead box I3","[FOXI3_HUMAN|Reviewed]RecName: Full=Forkhead box protein I3;"]
[3455,"'IFNAR2'",204,154,167,175,"04620///Toll-like receptor signaling pathway+++05162///Measles+++04060///Cytokine-cytokine receptor interaction+++04380///Osteoclast differentiation+++04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05168///Herpes simplex infection+++05200///Pathways in cancer+++04630///Jak-STAT signaling pathway+++04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05164///Influenza A+++05160///Hepatitis C",{"$nulls":3},"GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0019962///type I interferon binding+++GO:0019901///protein kinase binding+++GO:0004905///type I interferon receptor activity+++GO:0005515///protein binding","GO:0019221///cytokine-mediated signaling pathway+++GO:0007259///JAK-STAT cascade+++GO:0009615///response to virus+++GO:0035455///response to interferon-alpha+++GO:0060338///regulation of type I interferon-mediated signaling pathway+++GO:0060337///type I interferon signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0051607///defense response to virus+++GO:0035456///response to interferon-beta","interferon alpha and beta receptor subunit 2","[INAR2_HUMAN|Reviewed]RecName: Full=Interferon alpha/beta receptor 2; Short=IFN-R-2; Short=IFN-alpha binding protein; Short=IFN-alpha/beta receptor 2; AltName: Full=Interferon alpha binding protein; AltName: Full=Type I interferon receptor 2; Flags: Precursor;+++[C9JCU0_HUMAN|Unreviewed]SubName: Full=Interferon alpha/beta receptor 2 {ECO:0000313|Ensembl:ENSP00000403569}; Flags: Fragment;+++[C9JM33_HUMAN|Unreviewed]SubName: Full=Interferon alpha/beta receptor 2 {ECO:0000313|Ensembl:ENSP00000402311}; Flags: Fragment;+++[C9K067_HUMAN|Unreviewed]SubName: Full=Interferon alpha/beta receptor 2 {ECO:0000313|Ensembl:ENSP00000413160};+++[F8WDE1_HUMAN|Unreviewed]SubName: Full=Interferon alpha/beta receptor 2 {ECO:0000313|Ensembl:ENSP00000371673};+++[H7C176_HUMAN|Unreviewed]SubName: Full=Interferon alpha/beta receptor 2 {ECO:0000313|Ensembl:ENSP00000398799}; Flags: Fragment;+++[Q9BUA0_HUMAN|Unreviewed]SubName: Full=Interferon (Alpha, beta and omega) receptor 2 {ECO:0000313|EMBL:AAH02793.1};+++[S6FRS2_HUMAN|Unreviewed]SubName: Full=Interferon (Alpha, beta and omega) receptor 2 {ECO:0000313|EMBL:CDG37809.1}; Flags: Fragment;"]
[346389,"'MACC1'",5.06,7.27,4.15,5.49333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008083///growth factor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0010469///regulation of signaling receptor activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051781///positive regulation of cell division","MET transcriptional regulator MACC1","[MACC1_HUMAN|Reviewed]RecName: Full=Metastasis-associated in colon cancer protein 1; AltName: Full=SH3 domain-containing protein 7a5;"]
[347731,"'LRRTM3'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0030054///cell junction+++GO:0099061///integral component of postsynaptic density membrane+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane","GO:0004860///protein kinase inhibitor activity","GO:0099054///presynapse assembly+++GO:0051965///positive regulation of synapse assembly+++GO:1902004///positive regulation of amyloid-beta formation","leucine rich repeat transmembrane neuronal 3","[LRRT3_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat transmembrane neuronal protein 3; Flags: Precursor;"]
[3481,"'IGF2'",1962,3149,1773,2294.66666666667,"05200///Pathways in cancer+++04010///MAPK signaling pathway+++05225///Hepatocellular carcinoma+++04151///PI3K-Akt signaling pathway+++05205///Proteoglycans in cancer+++04014///Ras signaling pathway","H00033///Adrenal carcinoma+++H00048///Hepatocellular carcinoma+++H00711///Russell-Silver syndrome+++H00713///Beckwith-Wiedemann syndrome",null,null,"GO:0005576///extracellular region+++GO:0031093///platelet alpha granule lumen+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0008083///growth factor activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005179///hormone activity+++GO:0005158///insulin receptor binding+++GO:0048018///receptor ligand activity","GO:0001503///ossification+++GO:0040018///positive regulation of multicellular organism growth+++GO:0002576///platelet degranulation+++GO:0001649///osteoblast differentiation+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0031017///exocrine pancreas development+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0044267///cellular protein metabolic process+++GO:0008286///insulin receptor signaling pathway+++GO:0051781///positive regulation of cell division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051146///striated muscle cell differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0060669///embryonic placenta morphogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0006006///glucose metabolic process+++GO:0001701///in utero embryonic development+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0009887///animal organ morphogenesis+++GO:0001501///skeletal system development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000467///positive regulation of glycogen (starch) synthase activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0001892///embryonic placenta development+++GO:0008284///positive regulation of cell proliferation+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0031056///regulation of histone modification+++GO:0043085///positive regulation of catalytic activity+++GO:0051147///regulation of muscle cell differentiation+++GO:0010469///regulation of signaling receptor activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0005975///carbohydrate metabolic process","insulin like growth factor 2","[IGF2_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor II; Short=IGF-II; AltName: Full=Somatomedin-A; AltName: Full=T3M-11-derived growth factor; Contains: RecName: Full=Insulin-like growth factor II; Contains: RecName: Full=Insulin-like growth factor II Ala-25 Del; Contains: RecName: Full=Preptin; Flags: Precursor;+++[A0A024RCE6_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 (Somatomedin A), isoform CRA_a {ECO:0000313|EMBL:EAX02486.1};+++[A0A2R8Y747_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor II {ECO:0000313|Ensembl:ENSP00000495715};+++[B2MUX6_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 {ECO:0000313|EMBL:ACC95538.1};+++[E3UN46_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor II transcript variant 3 isoform 1 {ECO:0000313|EMBL:ADO21455.1}; Flags: Fragment;"]
[348654,"'GEN1'",247,377,323,315.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005634///nucleus","GO:0000400///four-way junction DNA binding+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0004520///endodeoxyribonuclease activity+++GO:0017108///5'-flap endonuclease activity+++GO:0003697///single-stranded DNA binding+++GO:0016787///hydrolase activity+++GO:0008311///double-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0003690///double-stranded DNA binding+++GO:0008821///crossover junction endodeoxyribonuclease activity+++GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0051908///double-stranded DNA 5'-3' exodeoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0045145///single-stranded DNA 5'-3' exodeoxyribonuclease activity+++GO:0003824///catalytic activity+++GO:0004518///nuclease activity+++GO:0048256///flap endonuclease activity+++GO:0004519///endonuclease activity","GO:0000738///DNA catabolic process, exonucleolytic+++GO:0072422///signal transduction involved in DNA damage checkpoint+++GO:0031297///replication fork processing+++GO:0000724///double-strand break repair via homologous recombination+++GO:0071140///resolution of mitotic recombination intermediates+++GO:0070914///UV-damage excision repair+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006281///DNA repair+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0071139///resolution of recombination intermediates+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010824///regulation of centrosome duplication","GEN1, Holliday junction 5' flap endonuclease","[GEN_HUMAN|Reviewed]RecName: Full=Flap endonuclease GEN homolog 1; EC=3.1.-.-;+++[A0A087WXY3_HUMAN|Unreviewed]SubName: Full=Flap endonuclease GEN homolog 1 {ECO:0000313|Ensembl:ENSP00000481385}; Flags: Fragment;+++[E9PLG0_HUMAN|Unreviewed]SubName: Full=Flap endonuclease GEN homolog 1 {ECO:0000313|Ensembl:ENSP00000435143}; Flags: Fragment;+++[E9PM30_HUMAN|Unreviewed]SubName: Full=Flap endonuclease GEN homolog 1 {ECO:0000313|Ensembl:ENSP00000433180}; Flags: Fragment;"]
[3487,"'IGFBP4'",1630,1608,1661,1633,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region","GO:0019838///growth factor binding+++GO:0005102///signaling receptor binding+++GO:0031995///insulin-like growth factor II binding+++GO:0005515///protein binding+++GO:0031994///insulin-like growth factor I binding+++GO:0005520///insulin-like growth factor binding","GO:0043410///positive regulation of MAPK cascade+++GO:0001501///skeletal system development+++GO:0040008///regulation of growth+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0044342///type B pancreatic cell proliferation+++GO:0043687///post-translational protein modification+++GO:0008283///cell proliferation+++GO:0010906///regulation of glucose metabolic process+++GO:0006259///DNA metabolic process+++GO:0006954///inflammatory response+++GO:0044267///cellular protein metabolic process+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0001558///regulation of cell growth+++GO:0007165///signal transduction","insulin like growth factor binding protein 4","[IBP4_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor-binding protein 4; Short=IBP-4; Short=IGF-binding protein 4; Short=IGFBP-4; Flags: Precursor;+++[A0A024R1U8_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor binding protein 4, isoform CRA_a {ECO:0000313|EMBL:EAW60665.1};"]
[35,"'ACADS'",123,137,124,128,"00280///Valine, leucine and isoleucine degradation+++00071///Fatty acid degradation+++00650///Butanoate metabolism+++01110///Biosynthesis of secondary metabolites+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways","H00525///Disorders of mitochondrial fatty-acid oxidation+++H01980///SCAD deficiency",null,"R01175///butanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA+++R03172///(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase   (S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor+++R02661///2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase   2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor+++R04751///hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2+++R01178///short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein","GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion","GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016491///oxidoreductase activity+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004085///butyryl-CoA dehydrogenase activity+++GO:0050660///flavin adenine dinucleotide binding","GO:0046359///butyrate catabolic process+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0055114///oxidation-reduction process+++GO:0006631///fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006635///fatty acid beta-oxidation","acyl-CoA dehydrogenase short chain","[ACADS_HUMAN|Reviewed]RecName: Full=Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Short=SCAD; EC=1.3.8.1; AltName: Full=Butyryl-CoA dehydrogenase; Flags: Precursor;+++[B4DUH1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51323, highly similar to Short-chain specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000313|EMBL:BAG62333.1};+++[D4QEZ8_HUMAN|Unreviewed]SubName: Full=Short-chain acyl-CoA dehydrogenase {ECO:0000313|EMBL:BAJ05798.1};+++[E5KSD5_HUMAN|Unreviewed]SubName: Full=Acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain {ECO:0000313|EMBL:EAW98218.1}; SubName: Full=Mitochondrial short-chain specific acyl-CoA dehydrogenase {ECO:0000313|EMBL:ADP91814.1};+++[E9PE82_HUMAN|Unreviewed]SubName: Full=Short-chain-specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000401045};"]
[353322,"'ANKRD37'",84,54,78,72,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01817///Beukes hip dysplasia (BHD)",null,null,"GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016790///thiolester hydrolase activity+++GO:0071567///UFM1 hydrolase activity","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0006508///proteolysis","ankyrin repeat domain 37","[ANR37_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 37; AltName: Full=Low-density lipoprotein receptor-related protein 2-binding protein; Short=hLrp2bp;+++[B4E066_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50037, highly similar to Ankyrin repeat domain-containing protein 37 {ECO:0000313|EMBL:BAG64328.1};+++[D6RFF5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 37 {ECO:0000313|Ensembl:ENSP00000421529}; Flags: Fragment;"]
[356,"'FASLG'",1,0,0,0.333333333333333,"05200///Pathways in cancer+++05332///Graft-versus-host disease+++05161///Hepatitis B+++05205///Proteoglycans in cancer+++05163///Human cytomegalovirus infection+++05162///Measles+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04068///FoxO signaling pathway+++04217///Necroptosis+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++01524///Platinum drug resistance+++05143///African trypanosomiasis+++04940///Type I diabetes mellitus+++05330///Allograft rejection+++04722///Neurotrophin signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04060///Cytokine-cytokine receptor interaction+++05165///Human papillomavirus infection+++05320///Autoimmune thyroid disease+++04210///Apoptosis+++05168///Herpes simplex infection+++05164///Influenza A+++04010///MAPK signaling pathway","H00108///Autoimmune lymphoproliferative syndromes (ALPS)",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0005887///integral component of plasma membrane+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0043202///lysosomal lumen+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0045121///membrane raft+++GO:0005764///lysosome+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0060205///cytoplasmic vesicle lumen","GO:0005515///protein binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0005123///death receptor binding","GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0006955///immune response+++GO:0008284///positive regulation of cell proliferation+++GO:0006915///apoptotic process+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:1903514///release of sequestered calcium ion into cytosol by endoplasmic reticulum+++GO:0070231///T cell apoptotic process+++GO:0010469///regulation of signaling receptor activity+++GO:0097527///necroptotic signaling pathway+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0070266///necroptotic process+++GO:0007267///cell-cell signaling+++GO:0007165///signal transduction+++GO:0048388///endosomal lumen acidification+++GO:0070848///response to growth factor+++GO:0030644///cellular chloride ion homeostasis+++GO:0097190///apoptotic signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046666///retinal cell programmed cell death+++GO:0006925///inflammatory cell apoptotic process+++GO:0016525///negative regulation of angiogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process","Fas ligand","[TNFL6_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 6; AltName: Full=Apoptosis antigen ligand; Short=APTL; AltName: Full=CD95 ligand; Short=CD95-L; AltName: Full=Fas antigen ligand; Short=Fas ligand; Short=FasL; AltName: CD_antigen=CD178; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 6, membrane form; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 6, soluble form; AltName: Full=Receptor-binding FasL ectodomain; AltName: Full=Soluble Fas ligand; Short=sFasL; Contains: RecName: Full=ADAM10-processed FasL form; Short=APL; Contains: RecName: Full=FasL intracellular domain; Short=FasL ICD; AltName: Full=SPPL2A-processed FasL form; Short=SPA;+++[A0A0H3VB22_HUMAN|Unreviewed]SubName: Full=Mutant tumor necrosis factor family member 6 {ECO:0000313|EMBL:AJT60329.1};+++[Q0VHD7_HUMAN|Unreviewed]SubName: Full=CD95 ligand {ECO:0000313|EMBL:AAX49569.1};+++[Q53ZZ1_HUMAN|Unreviewed]SubName: Full=FAS ligand {ECO:0000313|EMBL:AAO43991.1}; SubName: Full=Fas ligand (TNF superfamily, member 6) {ECO:0000313|EMBL:ABK41922.1}; SubName: Full=Fas ligand (TNF superfamily, member 6), isoform CRA_b {ECO:0000313|EMBL:EAW90936.1}; SubName: Full=Tumor necrosis factor ligand 1A {ECO:0000313|EMBL:CTQ86077.1}; SubName: Full=cDNA, FLJ95775, Homo sapiens tumor necrosis factor (ligand) superfamily, member 6(TNFSF6), mRNA {ECO:0000313|EMBL:BAG37389.1};"]
[3587,"'IL10RA'",1,2,3,2,"05163///Human cytomegalovirus infection+++05169///Epstein-Barr virus infection+++05145///Toxoplasmosis+++04630///Jak-STAT signaling pathway+++05152///Tuberculosis+++04060///Cytokine-cytokine receptor interaction","H00286///Crohn's disease+++H01227///Inflammatory bowel disease (IBD)",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0019969///interleukin-10 binding+++GO:0038023///signaling receptor activity+++GO:0004920///interleukin-10 receptor activity+++GO:0005515///protein binding","GO:0050807///regulation of synapse organization+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide","interleukin 10 receptor subunit alpha","[I10R1_HUMAN|Reviewed]RecName: Full=Interleukin-10 receptor subunit alpha; Short=IL-10 receptor subunit alpha; Short=IL-10R subunit alpha; Short=IL-10RA; AltName: Full=CDw210a; AltName: Full=Interleukin-10 receptor subunit 1; Short=IL-10R subunit 1; Short=IL-10R1; AltName: CD_antigen=CD210; Flags: Precursor;+++[E9PKU2_HUMAN|Unreviewed]SubName: Full=Interleukin-10 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000435317};+++[E9PPU4_HUMAN|Unreviewed]SubName: Full=Interleukin-10 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000436328};+++[H2DF05_HUMAN|Unreviewed]SubName: Full=Interleukin 10 alpha receptor {ECO:0000313|EMBL:AEX60806.1};"]
[360226,"'PRSS41'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0043229///intracellular organelle+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane","GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity","GO:0006508///proteolysis","serine protease 41","[PRS41_HUMAN|Reviewed]RecName: Full=Serine protease 41; EC=3.4.21.-; AltName: Full=Testis serine protease 1; Short=TESSP-1; Flags: Precursor;"]
[3624,"'INHBA'",58,47,84,63,"04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++04350///TGF-beta signaling pathway",null,"M00681///Activin signaling",null,"GO:0043512///inhibin A complex+++GO:0005615///extracellular space+++GO:0043509///activin A complex+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm","GO:0005179///hormone activity+++GO:0070699///type II activin receptor binding+++GO:0005125///cytokine activity+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity+++GO:0005102///signaling receptor binding+++GO:0008083///growth factor activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0034711///inhibin binding+++GO:0005515///protein binding+++GO:0017046///peptide hormone binding","GO:0021773///striatal medium spiny neuron differentiation+++GO:0048468///cell development+++GO:0042541///hemoglobin biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008584///male gonad development+++GO:0007050///cell cycle arrest+++GO:0007166///cell surface receptor signaling pathway+++GO:0045786///negative regulation of cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0030308///negative regulation of cell growth+++GO:0042476///odontogenesis+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0043408///regulation of MAPK cascade+++GO:0042701///progesterone secretion+++GO:0007399///nervous system development+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0042493///response to drug+++GO:0042326///negative regulation of phosphorylation+++GO:0010628///positive regulation of gene expression+++GO:0045650///negative regulation of macrophage differentiation+++GO:0035987///endodermal cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045077///negative regulation of interferon-gamma biosynthetic process+++GO:0097154///GABAergic neuron differentiation+++GO:0060021///roof of mouth development+++GO:0032924///activin receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048333///mesodermal cell differentiation+++GO:0071397///cellular response to cholesterol+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0045578///negative regulation of B cell differentiation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0051799///negative regulation of hair follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0010469///regulation of signaling receptor activity+++GO:0009611///response to wounding+++GO:0001541///ovarian follicle development+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0060279///positive regulation of ovulation+++GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0006952///defense response+++GO:0042981///regulation of apoptotic process+++GO:0007267///cell-cell signaling+++GO:0061029///eyelid development in camera-type eye+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0030218///erythrocyte differentiation+++GO:0001707///mesoderm formation+++GO:0030154///cell differentiation+++GO:0060395///SMAD protein signal transduction+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0001942///hair follicle development+++GO:0046880///regulation of follicle-stimulating hormone secretion","inhibin subunit beta A","[INHBA_HUMAN|Reviewed]RecName: Full=Inhibin beta A chain; AltName: Full=Activin beta-A chain; AltName: Full=Erythroid differentiation protein; Short=EDF; Flags: Precursor;+++[A4D1W7_HUMAN|Unreviewed]SubName: Full=Inhibin, beta A (Activin A, activin AB alpha polypeptide) {ECO:0000313|EMBL:EAL24001.1}; SubName: Full=Inhibin, beta A (Activin A, activin AB alpha polypeptide), isoform CRA_a {ECO:0000313|EMBL:EAW94139.1}; SubName: Full=cDNA FLJ75379, highly similar to Homo sapiens inhibin, beta A (activin A, activin AB alpha polypeptide), mRNA {ECO:0000313|EMBL:BAF83273.1};"]
[3641,"'INSL4'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005179///hormone activity+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005102///signaling receptor binding","GO:0010469///regulation of signaling receptor activity+++GO:0007267///cell-cell signaling+++GO:0007565///female pregnancy+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0007275///multicellular organism development","insulin like 4","[INSL4_HUMAN|Reviewed]RecName: Full=Early placenta insulin-like peptide; Short=EPIL; AltName: Full=Insulin-like peptide 4; AltName: Full=Placentin; Contains: RecName: Full=Early placenta insulin-like peptide B chain; Contains: RecName: Full=Early placenta insulin-like peptide A chain; Flags: Precursor;"]
[3672,"'ITGA1'",161,107,95,121,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04512///ECM-receptor interaction+++04640///Hematopoietic cell lineage+++05414///Dilated cardiomyopathy (DCM)+++04151///PI3K-Akt signaling pathway+++05410///Hypertrophic cardiomyopathy (HCM)+++04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++05165///Human papillomavirus infection",{"$nulls":3},"GO:0016020///membrane+++GO:0034665///integrin alpha1-beta1 complex+++GO:0070062///extracellular exosome+++GO:0001669///acrosomal vesicle+++GO:0005886///plasma membrane+++GO:0043204///perikaryon+++GO:0043005///neuron projection+++GO:0045178///basal part of cell+++GO:0005925///focal adhesion+++GO:0045121///membrane raft+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0009897///external side of plasma membrane+++GO:0008305///integrin complex","GO:0005518///collagen binding+++GO:0098639///collagen binding involved in cell-matrix adhesion+++GO:0046872///metal ion binding+++GO:0019903///protein phosphatase binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding","GO:0043525///positive regulation of neuron apoptotic process+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0030198///extracellular matrix organization+++GO:0007160///cell-matrix adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0007229///integrin-mediated signaling pathway+++GO:0048812///neuron projection morphogenesis+++GO:0060326///cell chemotaxis+++GO:0006936///muscle contraction+++GO:0045123///cellular extravasation+++GO:0030593///neutrophil chemotaxis+++GO:0042311///vasodilation+++GO:0007155///cell adhesion+++GO:0000187///activation of MAPK activity+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway","integrin subunit alpha 1","[ITA1_HUMAN|Reviewed]RecName: Full=Integrin alpha-1; AltName: Full=CD49 antigen-like family member A; AltName: Full=Laminin and collagen receptor; AltName: Full=VLA-1; AltName: CD_antigen=CD49a; Flags: Precursor;"]
[3684,"'ITGAM'",1,0,0,0.333333333333333,"04015///Rap1 signaling pathway+++04145///Phagosome+++04610///Complement and coagulation cascades+++05146///Amoebiasis+++05150///Staphylococcus aureus infection+++05152///Tuberculosis+++04810///Regulation of actin cytoskeleton+++05221///Acute myeloid leukemia+++05134///Legionellosis+++04514///Cell adhesion molecules (CAMs)+++05202///Transcriptional misregulation in cancer+++05133///Pertussis+++05140///Leishmaniasis+++04670///Leukocyte transendothelial migration+++04640///Hematopoietic cell lineage",{"$nulls":3},"GO:0044853///plasma membrane raft+++GO:0034688///integrin alphaM-beta2 complex+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0045121///membrane raft+++GO:0009986///cell surface+++GO:0070821///tertiary granule membrane+++GO:0009897///external side of plasma membrane+++GO:0008305///integrin complex+++GO:0016020///membrane+++GO:0035579///specific granule membrane","GO:0046982///protein heterodimerization activity+++GO:0001851///complement component C3b binding+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding+++GO:0001540///amyloid-beta binding+++GO:0005515///protein binding","GO:2000363///positive regulation of prostaglandin-E synthase activity+++GO:0030198///extracellular matrix organization+++GO:0043312///neutrophil degranulation+++GO:0010668///ectodermal cell differentiation+++GO:0006911///phagocytosis, engulfment+++GO:0032930///positive regulation of superoxide anion generation+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0001774///microglial cell activation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0150064///vertebrate eye-specific patterning+++GO:0007229///integrin-mediated signaling pathway+++GO:0045963///negative regulation of dopamine metabolic process+++GO:1903980///positive regulation of microglial cell activation+++GO:0150062///complement-mediated synapse pruning+++GO:0002376///immune system process+++GO:0007155///cell adhesion+++GO:0060100///positive regulation of phagocytosis, engulfment+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0043315///positive regulation of neutrophil degranulation+++GO:0045087///innate immune response+++GO:0050900///leukocyte migration+++GO:1901216///positive regulation of neuron death+++GO:0097242///amyloid-beta clearance+++GO:1905114///cell surface receptor signaling pathway involved in cell-cell signaling","integrin subunit alpha M","[ITAM_HUMAN|Reviewed]RecName: Full=Integrin alpha-M; AltName: Full=CD11 antigen-like family member B; AltName: Full=CR-3 alpha chain; AltName: Full=Cell surface glycoprotein MAC-1 subunit alpha; AltName: Full=Leukocyte adhesion receptor MO1; AltName: Full=Neutrophil adherence receptor; AltName: CD_antigen=CD11b; Flags: Precursor;+++[H3BMV4_HUMAN|Unreviewed]SubName: Full=Integrin alpha-M {ECO:0000313|Ensembl:ENSP00000454568}; Flags: Fragment;+++[I3NI33_HUMAN|Unreviewed]SubName: Full=Integrin alpha-M {ECO:0000313|Ensembl:ENSP00000461850}; Flags: Fragment;"]
[3703,"'STT3A'",3169,2859,2821,2949.66666666667,"00510///N-Glycan biosynthesis+++01100///Metabolic pathways+++04141///Protein processing in endoplasmic reticulum+++00513///Various types of N-glycan biosynthesis","H00118///Congenital disorders of glycosylation (CDG) type I","M00072///N-glycosylation by oligosaccharyltransferase","R05976///Protein asparagine + G00008 <=> Dolichyl diphosphate + G00009+++R04216///dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase   Dolichyl diphosphooligosaccharide + Protein asparagine <=> Dolichyl diphosphate + Glycoprotein with the oligosaccharide chain attached by N-glycosyl linkage to protein L-asparagine","GO:0005783///endoplasmic reticulum+++GO:0008250///oligosaccharyltransferase complex+++GO:0035000///oligosaccharyltransferase III complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004576///oligosaccharyl transferase activity+++GO:0004579///dolichyl-diphosphooligosaccharide-protein glycotransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0006486///protein glycosylation+++GO:0043686///co-translational protein modification+++GO:0018279///protein N-linked glycosylation via asparagine","STT3A, catalytic subunit of the oligosaccharyltransferase complex","[STT3A_HUMAN|Reviewed]RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; Short=Oligosaccharyl transferase subunit STT3A; Short=STT3-A; EC=2.4.99.18; AltName: Full=B5; AltName: Full=Integral membrane protein 1; AltName: Full=Transmembrane protein TMC;+++[A0A0C4DH80_HUMAN|Unreviewed]SubName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A {ECO:0000313|Ensembl:ENSP00000435810}; Flags: Fragment;+++[E9PI32_HUMAN|Unreviewed]SubName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A {ECO:0000313|Ensembl:ENSP00000436558}; Flags: Fragment;+++[E9PN73_HUMAN|Unreviewed]SubName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A {ECO:0000313|Ensembl:ENSP00000432912}; Flags: Fragment;+++[H0YET6_HUMAN|Unreviewed]SubName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A {ECO:0000313|Ensembl:ENSP00000436523}; Flags: Fragment;"]
[373156,"'GSTK1'",1634,1766,1617,1672.33333333333,"00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00480///Glutathione metabolism+++04146///Peroxisome+++05204///Chemical carcinogenesis",null,null,"R09409///glutathione-S-transferase   Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH+++R07091///S-(2,2-dichloro-1-hydroxy)ethyl-glutathione 2,2-dichloroacetaldehyde-lyase (glutathione-forming)   2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione+++R07092///1,1-dichloroethylene-epoxide:glutathione S-(chloroepoxyethyl)transferase [2-(S-glutathionyl)acetyl-chloride-forming]   1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid+++R07069///3,4-dihydro-3-hydroxy-4-S-glutathionyl bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene+++R07113///1,2-dibromoethane:glutathione ethylenetransferase (episulfonium-forming)   1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid+++R03522///RX:glutathione R-transferase   RX + Glutathione <=> Halide + R-S-Glutathione+++R07070///2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene+++R07093///chloroacetyl-chloride:glutathione S-chloroacetyltransferase   Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid+++R08280///4-glutathionyl cyclophosphamide hydrolase   Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O+++R07094///2-(S-glutathionyl)acetyl-chloride:glutathione 2-(S-glutathionyl)acetyltransferase   2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid+++R07026///1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene+++R07002///(1R)-hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene+++R07084///7,8-dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene hydrolase   Benzo[a]pyrene-7,8-diol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O+++R07025///1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene+++R07083///4,5-dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene glutathione-lyase (epoxide-forming)   Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene+++R07100///trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase   Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid+++R07004///(1S)-hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene+++R07116///2-bromoacetaldehyde:glutathione S-(formylmethyl)transferase   2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid+++R07024///1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene+++R07023///1-nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene+++R07003///(1R)-glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene","GO:0005739///mitochondrion+++GO:0005782///peroxisomal matrix+++GO:0005759///mitochondrial matrix+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005777///peroxisome+++GO:0005622///intracellular+++GO:0005829///cytosol","GO:0005102///signaling receptor binding+++GO:0004602///glutathione peroxidase activity+++GO:0004364///glutathione transferase activity+++GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016740///transferase activity","GO:0055114///oxidation-reduction process+++GO:0006749///glutathione metabolic process+++GO:0006625///protein targeting to peroxisome+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process+++GO:0030855///epithelial cell differentiation","glutathione S-transferase kappa 1","[GSTK1_HUMAN|Reviewed]RecName: Full=Glutathione S-transferase kappa 1; EC=2.5.1.18; AltName: Full=GST 13-13; AltName: Full=GST class-kappa; AltName: Full=GSTK1-1; Short=hGSTK1; AltName: Full=Glutathione S-transferase subunit 13;+++[C9JNT3_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase kappa 1 {ECO:0000313|Ensembl:ENSP00000408341}; Flags: Fragment;+++[E9PFN5_HUMAN|Unreviewed]RecName: Full=Glutathione S-transferase kappa {ECO:0000256|PIRNR:PIRNR006386}; EC=2.5.1.18 {ECO:0000256|PIRNR:PIRNR006386};+++[Q2NLC8_HUMAN|Unreviewed]SubName: Full=GSTK1 protein {ECO:0000313|EMBL:AAI10601.1}; Flags: Fragment;+++[Q6FII1_HUMAN|Unreviewed]RecName: Full=Glutathione S-transferase kappa {ECO:0000256|PIRNR:PIRNR006386}; EC=2.5.1.18 {ECO:0000256|PIRNR:PIRNR006386};"]
[3741,"'KCNA5'",0,1,0,0.333333333333333,null,"H00731///Atrial fibrillation",null,null,"GO:0045121///membrane raft+++GO:0005901///caveola+++GO:0016021///integral component of membrane+++GO:0014704///intercalated disc+++GO:0046691///intracellular canaliculus+++GO:0016020///membrane+++GO:0034705///potassium channel complex+++GO:0005783///endoplasmic reticulum+++GO:0009986///cell surface+++GO:0030018///Z disc+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane","GO:0086089///voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization+++GO:0005515///protein binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015271///outward rectifier potassium channel activity+++GO:0051393///alpha-actinin binding+++GO:0086087///voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization+++GO:0086090///voltage-gated potassium channel activity involved in SA node cell action potential repolarization+++GO:0097110///scaffold protein binding+++GO:0019901///protein kinase binding+++GO:0005102///signaling receptor binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005216///ion channel activity","GO:0098914///membrane repolarization during atrial cardiac muscle cell action potential+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0042391///regulation of membrane potential+++GO:0010033///response to organic substance+++GO:0019229///regulation of vasoconstriction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0071805///potassium ion transmembrane transport+++GO:0060081///membrane hyperpolarization+++GO:0006811///ion transport+++GO:0055093///response to hyperoxia+++GO:0051259///protein complex oligomerization+++GO:0042542///response to hydrogen peroxide+++GO:0001666///response to hypoxia+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0050796///regulation of insulin secretion+++GO:0086052///membrane repolarization during SA node cell action potential+++GO:0051260///protein homooligomerization+++GO:0009612///response to mechanical stimulus+++GO:0086050///membrane repolarization during bundle of His cell action potential+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0043266///regulation of potassium ion transport+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:0097623///potassium ion export across plasma membrane+++GO:0007219///Notch signaling pathway+++GO:0034765///regulation of ion transmembrane transport+++GO:0055075///potassium ion homeostasis+++GO:2000288///positive regulation of myoblast proliferation+++GO:0006813///potassium ion transport+++GO:0055085///transmembrane transport","potassium voltage-gated channel subfamily A member 5","[KCNA5_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily A member 5; AltName: Full=HPCN1; AltName: Full=Voltage-gated potassium channel HK2; AltName: Full=Voltage-gated potassium channel subunit Kv1.5;"]
[374860,"'ANKRD30B'",1,13,3,5.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","ankyrin repeat domain 30B","[AN30B_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 30B; AltName: Full=Serologically defined breast cancer antigen NY-BR-1.1 {ECO:0000303|PubMed:11280766};"]
[374887,"'YJEFN3'",69,82,96,82.3333333333333,"01100///Metabolic pathways+++05010///Alzheimer's disease+++05016///Huntington's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++00190///Oxidative phosphorylation+++04723///Retrograde endocannabinoid signaling+++04714///Thermogenesis+++05012///Parkinson's disease",null,"M00146///NADH dehydrogenase (ubiquinone) 1 alpha subcomplex",null,"GO:0005739///mitochondrion","GO:0052857///NADPHX epimerase activity+++GO:0052856///NADHX epimerase activity","GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0097190///apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0010952///positive regulation of peptidase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030308///negative regulation of cell growth+++GO:0035458///cellular response to interferon-beta+++GO:0072593///reactive oxygen species metabolic process+++GO:0071300///cellular response to retinoic acid+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045039///protein import into mitochondrial inner membrane","YjeF N-terminal domain containing 3","[YJEN3_HUMAN|Reviewed]RecName: Full=YjeF N-terminal domain-containing protein 3; Short=YjeF_N3; Short=hYjeF_N3;+++[A0A087WUA6_HUMAN|Unreviewed]SubName: Full=YjeF N-terminal domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000478505};+++[Q6ZT45_HUMAN|Unreviewed]SubName: Full=FLJ44968 protein, isoform CRA_c {ECO:0000313|EMBL:EAW84829.1}; SubName: Full=YJEFN3 protein {ECO:0000313|EMBL:AAH93948.1}; SubName: Full=cDNA FLJ44968 fis, clone BRAWH2016562 {ECO:0000313|EMBL:BAC86749.1};"]
[375033,"'PEAR1'",178,196,220,198,{"$nulls":4},"GO:0016020///membrane+++GO:0001891///phagocytic cup+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0038023///signaling receptor activity","GO:0070527///platelet aggregation+++GO:0043654///recognition of apoptotic cell+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0043491///protein kinase B signaling","platelet endothelial aggregation receptor 1","[PEAR1_HUMAN|Reviewed]RecName: Full=Platelet endothelial aggregation receptor 1; Short=hPEAR1; AltName: Full=Multiple epidermal growth factor-like domains protein 12; Short=Multiple EGF-like domains protein 12; Flags: Precursor;+++[A6PVP2_HUMAN|Unreviewed]SubName: Full=Platelet endothelial aggregation receptor 1 {ECO:0000313|Ensembl:ENSP00000389742}; Flags: Fragment;+++[F2Z2F7_HUMAN|Unreviewed]SubName: Full=Platelet endothelial aggregation receptor 1 {ECO:0000313|Ensembl:ENSP00000397870};"]
[375248,"'ANKRD36'",91.12,81.61,66.5,79.7433333333333,{"$nulls":5},"GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0008200///ion channel inhibitor activity","GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination","ankyrin repeat domain 36","[AN36A_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 36A;+++[A0A087X037_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36A {ECO:0000313|Ensembl:ENSP00000483076};+++[A0A1W2PNQ7_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36A {ECO:0000313|Ensembl:ENSP00000491007};+++[A0A1W2PS33_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36A {ECO:0000313|Ensembl:ENSP00000492584};+++[A1A5B0_HUMAN|Unreviewed]SubName: Full=ANKRD36 protein {ECO:0000313|EMBL:AAI28518.1};+++[A2VCN4_HUMAN|Unreviewed]SubName: Full=ANKRD36 protein {ECO:0000313|EMBL:AAI28263.1}; Flags: Fragment;"]
[375748,"'ERCC6L2'",299.01,301,250,283.336666666667,{"$nulls":4},"GO:0005813///centrosome+++GO:0005739///mitochondrion+++GO:0005815///microtubule organizing center+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex","GO:0004386///helicase activity+++GO:0000166///nucleotide binding+++GO:0019901///protein kinase binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity","GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0034614///cellular response to reactive oxygen species+++GO:0006974///cellular response to DNA damage stimulus","ERCC excision repair 6 like 2","[ER6L2_HUMAN|Reviewed]RecName: Full=DNA excision repair protein ERCC-6-like 2; EC=3.6.4.-; AltName: Full=DNA repair and recombination protein RAD26-like;+++[A0A024R9Q0_HUMAN|Unreviewed]SubName: Full=Chromosome 9 open reading frame 102, isoform CRA_a {ECO:0000313|EMBL:EAW92641.1};+++[F2Z2R4_HUMAN|Unreviewed]SubName: Full=DNA excision repair protein ERCC-6-like 2 {ECO:0000313|Ensembl:ENSP00000409751};+++[H0Y3T7_HUMAN|Unreviewed]SubName: Full=DNA excision repair protein ERCC-6-like 2 {ECO:0000313|Ensembl:ENSP00000384215}; Flags: Fragment;+++[H7BXQ9_HUMAN|Unreviewed]SubName: Full=DNA excision repair protein ERCC-6-like 2 {ECO:0000313|Ensembl:ENSP00000320939}; Flags: Fragment;+++[S4R327_HUMAN|Unreviewed]SubName: Full=DNA excision repair protein ERCC-6-like 2 {ECO:0000313|Ensembl:ENSP00000473877}; Flags: Fragment;+++[X6RE28_HUMAN|Unreviewed]SubName: Full=DNA excision repair protein ERCC-6-like 2 {ECO:0000313|Ensembl:ENSP00000395345}; Flags: Fragment;"]
[3763,"'KCNJ6'",0,0,2,0.666666666666667,"05032///Morphine addiction+++04728///Dopaminergic synapse+++04727///GABAergic synapse+++04726///Serotonergic synapse+++04713///Circadian entrainment+++04915///Estrogen signaling pathway+++04725///Cholinergic synapse+++04723///Retrograde endocannabinoid signaling+++04921///Oxytocin signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0008076///voltage-gated potassium channel complex+++GO:0016021///integral component of membrane","GO:0015467///G-protein activated inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005515///protein binding+++GO:0005242///inward rectifier potassium channel activity","GO:0034765///regulation of ion transmembrane transport+++GO:0006813///potassium ion transport+++GO:0006811///ion transport+++GO:1990573///potassium ion import across plasma membrane","potassium voltage-gated channel subfamily J member 6","[KCNJ6_HUMAN|Reviewed]RecName: Full=G protein-activated inward rectifier potassium channel 2; Short=GIRK-2; AltName: Full=BIR1; AltName: Full=Inward rectifier K(+) channel Kir3.2; AltName: Full=KATP-2; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 6;"]
[3781,"'KCNN2'",161,109.94,98.27,123.07,"04976///Bile secretion+++04911///Insulin secretion+++04726///Serotonergic synapse",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0009986///cell surface+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0005516///calmodulin binding+++GO:0051393///alpha-actinin binding+++GO:0016286///small conductance calcium-activated potassium channel activity+++GO:0015269///calcium-activated potassium channel activity+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding","GO:0071805///potassium ion transmembrane transport+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0006813///potassium ion transport+++GO:0098914///membrane repolarization during atrial cardiac muscle cell action potential","potassium calcium-activated channel subfamily N member 2","[KCNN2_HUMAN|Reviewed]RecName: Full=Small conductance calcium-activated potassium channel protein 2; Short=SK2; Short=SKCa 2; Short=SKCa2; AltName: Full=KCa2.2;+++[A0A0J9YW81_HUMAN|Unreviewed]SubName: Full=Small conductance calcium-activated potassium channel protein 2 {ECO:0000313|Ensembl:ENSP00000487849};+++[D6RGY7_HUMAN|Unreviewed]SubName: Full=Small conductance calcium-activated potassium channel protein 2 {ECO:0000313|Ensembl:ENSP00000421095};"]
[3796,"'KIF2A'",393,388,364,381.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01881///Complex cortical dysplasia with other brain malformations",null,null,"GO:0000922///spindle pole+++GO:0005871///kinesin complex+++GO:0005737///cytoplasm+++GO:0097228///sperm principal piece+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005819///spindle+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005876///spindle microtubule+++GO:0005874///microtubule+++GO:0005814///centriole+++GO:0120103///centriolar subdistal appendage+++GO:0016604///nuclear body+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0003777///microtubule motor activity+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0030154///cell differentiation+++GO:0000226///microtubule cytoskeleton organization+++GO:0007018///microtubule-based movement+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007399///nervous system development+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0090307///mitotic spindle assembly+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0030334///regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0007052///mitotic spindle organization+++GO:0007019///microtubule depolymerization","kinesin family member 2A","[KIF2A_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF2A; AltName: Full=Kinesin-2; Short=hK2;+++[B0AZS5_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[D6R9M0_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF2A {ECO:0000313|Ensembl:ENSP00000423542}; Flags: Fragment;+++[D6RD93_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF2A {ECO:0000313|Ensembl:ENSP00000425411}; Flags: Fragment;+++[H0Y8H2_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF2A {ECO:0000313|Ensembl:ENSP00000421041}; Flags: Fragment;"]
[3824,"'KLRD1'",4,4.27,10.94,6.40333333333333,"04650///Natural killer cell mediated cytotoxicity+++04612///Antigen processing and presentation",{"$nulls":3},"GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0009897///external side of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:1990405///protein antigen binding+++GO:0023030///MHC class Ib protein binding, via antigen binding groove+++GO:0004888///transmembrane signaling receptor activity+++GO:0030246///carbohydrate binding+++GO:0005515///protein binding+++GO:0023024///MHC class I protein complex binding","GO:0002228///natural killer cell mediated immunity+++GO:0007166///cell surface receptor signaling pathway+++GO:0045087///innate immune response+++GO:0050776///regulation of immune response","killer cell lectin like receptor D1","[KLRD1_HUMAN|Reviewed]RecName: Full=Natural killer cells antigen CD94; AltName: Full=KP43; AltName: Full=Killer cell lectin-like receptor subfamily D member 1; AltName: Full=NK cell receptor; AltName: CD_antigen=CD94;+++[E9PCX9_HUMAN|Unreviewed]SubName: Full=Natural killer cells antigen CD94 {ECO:0000313|Ensembl:ENSP00000344858};+++[F5GX94_HUMAN|Unreviewed]SubName: Full=Natural killer cells antigen CD94 {ECO:0000313|Ensembl:ENSP00000441074};+++[F5H2B7_HUMAN|Unreviewed]SubName: Full=Natural killer cells antigen CD94 {ECO:0000313|Ensembl:ENSP00000438669};+++[F6WZH4_HUMAN|Unreviewed]SubName: Full=Natural killer cells antigen CD94 {ECO:0000313|Ensembl:ENSP00000443584};+++[H0YFB8_HUMAN|Unreviewed]SubName: Full=Natural killer cells antigen CD94 {ECO:0000313|Ensembl:ENSP00000437880}; Flags: Fragment;+++[Q53ZY6_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily D isoform C {ECO:0000313|EMBL:AAP57386.1}; SubName: Full=Killer cell lectin-like receptor subfamily D, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW96172.1}; SubName: Full=cDNA FLJ75697, highly similar to Homo sapiens killer cell lectin-like receptor subfamily D, member 1 (KLRD1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84195.1};+++[Q8NFL9_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily D transcript B2 {ECO:0000313|EMBL:AAM70198.1};+++[Q8NFM0_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily D transcript 3 {ECO:0000313|EMBL:AAM70197.1};"]
[3856,"'KRT8'",18788,17077,19310,18391.6666666667,null,"H00726///Meesmann corneal dystrophy+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00944///Dowling-Degos disease+++H00667///Woolly hair+++H00717///Striate palmoplantar keratoderma+++H00649///Ectodermal dysplasia, pure hair-nail type (HNED)+++H00670///Monilethrix+++H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H01673///Palmoplantar keratoderma+++H00672///Pseudofolliculitis barbae+++H00584///Epidermolysis bullosa simplex+++H00684///Pachyonychia congenita+++H00693///Ichthyosis bullosa of Siemens+++H00724///White sponge nevus+++H00786///Hereditary hypotrichosis simplex+++H00707///Ichthyosis hystrix, Curth-Macklin type",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043034///costamere+++GO:0005882///intermediate filament+++GO:0071944///cell periphery+++GO:0016327///apicolateral plasma membrane+++GO:0042383///sarcolemma+++GO:0045095///keratin filament+++GO:0005654///nucleoplasm+++GO:0030018///Z disc+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0070062///extracellular exosome+++GO:0005911///cell-cell junction+++GO:0005634///nucleus+++GO:0045111///intermediate filament cytoskeleton+++GO:0016363///nuclear matrix","GO:0005198///structural molecule activity+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding+++GO:0005515///protein binding","GO:0097284///hepatocyte apoptotic process+++GO:0051599///response to hydrostatic pressure+++GO:0070268///cornification+++GO:0031424///keratinization+++GO:0051707///response to other organism+++GO:0045214///sarcomere organization+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0016032///viral process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway","keratin 8","[K2C8_HUMAN|Reviewed]RecName: Full=Keratin, type II cytoskeletal 8; AltName: Full=Cytokeratin-8; Short=CK-8; AltName: Full=Keratin-8; Short=K8; AltName: Full=Type-II keratin Kb8;+++[A0A0U1RQU6_HUMAN|Unreviewed]SubName: Full=Keratin, type II cytoskeletal 8 {ECO:0000313|Ensembl:ENSP00000489174};+++[F8VP67_HUMAN|Unreviewed]SubName: Full=Keratin, type II cytoskeletal 8 {ECO:0000313|Ensembl:ENSP00000450340}; Flags: Fragment;+++[F8VQY3_HUMAN|Unreviewed]SubName: Full=Keratin, type II cytoskeletal 8 {ECO:0000313|Ensembl:ENSP00000450228}; Flags: Fragment;+++[F8VUG2_HUMAN|Unreviewed]SubName: Full=Keratin, type II cytoskeletal 8 {ECO:0000313|Ensembl:ENSP00000447881}; Flags: Fragment;+++[F8W1U3_HUMAN|Unreviewed]SubName: Full=Keratin, type II cytoskeletal 8 {ECO:0000313|Ensembl:ENSP00000447040}; Flags: Fragment;+++[H0YIB2_HUMAN|Unreviewed]SubName: Full=Keratin, type II cytoskeletal 8 {ECO:0000313|Ensembl:ENSP00000449010}; Flags: Fragment;+++[Q7L4M3_HUMAN|Unreviewed]SubName: Full=KRT8 protein {ECO:0000313|EMBL:AAH08200.1};+++[Q969I0_HUMAN|Unreviewed]SubName: Full=KRT8 protein {ECO:0000313|EMBL:AAH11373.2}; Flags: Fragment;"]
[387104,"'SOGA3'",15.79,6.26,9,10.35,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane",null,"GO:0010506///regulation of autophagy","SOGA family member 3","[SOGA3_HUMAN|Reviewed]RecName: Full=Protein SOGA3; Flags: Precursor;+++[A0A1D5RMT3_HUMAN|Unreviewed]SubName: Full=Protein SOGA3 {ECO:0000313|Ensembl:ENSP00000431662}; Flags: Fragment;+++[A1L177_HUMAN|Unreviewed]SubName: Full=C6orf174 protein {ECO:0000313|EMBL:AAI27761.1}; Flags: Fragment;+++[A5PLQ8_HUMAN|Unreviewed]SubName: Full=C6orf174 protein {ECO:0000313|EMBL:AAI43044.1}; Flags: Fragment;+++[E9PJP2_HUMAN|Unreviewed]SubName: Full=Protein SOGA3 {ECO:0000313|Ensembl:ENSP00000435559};"]
[387758,"'FIBIN'",96,69,78,81,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005575///cellular_component+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region","GO:0003674///molecular_function+++GO:0042803///protein homodimerization activity","GO:0010042///response to manganese ion+++GO:0071548///response to dexamethasone+++GO:0008150///biological_process+++GO:0070528///protein kinase C signaling","fin bud initiation factor homolog","[FIBIN_HUMAN|Reviewed]RecName: Full=Fin bud initiation factor homolog; Flags: Precursor;"]
[388,"'RHOB'",4112,4126,3814,4017.33333333333,{"$nulls":4},"GO:0010008///endosome membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0032154///cleavage furrow+++GO:0005925///focal adhesion+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005938///cell cortex+++GO:0031902///late endosome membrane+++GO:0032153///cell division site+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005769///early endosome","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0019003///GDP binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding","GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0061154///endothelial tube morphogenesis+++GO:0071479///cellular response to ionizing radiation+++GO:0006886///intracellular protein transport+++GO:0007015///actin filament organization+++GO:0006915///apoptotic process+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0045786///negative regulation of cell cycle+++GO:0030334///regulation of cell migration+++GO:0051017///actin filament bundle assembly+++GO:0007275///multicellular organism development+++GO:0045766///positive regulation of angiogenesis+++GO:0015031///protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010595///positive regulation of endothelial cell migration+++GO:0007264///small GTPase mediated signal transduction+++GO:0008333///endosome to lysosome transport+++GO:0008360///regulation of cell shape+++GO:0043065///positive regulation of apoptotic process+++GO:0007155///cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0007266///Rho protein signal transduction+++GO:0001525///angiogenesis+++GO:0030154///cell differentiation+++GO:0000281///mitotic cytokinesis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0016477///cell migration+++GO:0070301///cellular response to hydrogen peroxide","ras homolog family member B","[RHOB_HUMAN|Reviewed]RecName: Full=Rho-related GTP-binding protein RhoB; AltName: Full=Rho cDNA clone 6; Short=h6; Flags: Precursor;+++[Q7Z4F6_HUMAN|Unreviewed]SubName: Full=MSTP081 {ECO:0000313|EMBL:AAQ13605.1};"]
[388335,"'TMEM220'",58,42,45,48.3333333333333,"00564///Glycerophospholipid metabolism+++04140///Autophagy - animal+++03040///Spliceosome+++03013///RNA transport+++04137///Mitophagy - animal+++00230///Purine metabolism+++03015///mRNA surveillance pathway",null,"M00430///Exon junction complex (EJC)","R01054///ADP-ribose ribophosphohydrolase ADP-ribose + H2O <=> AMP + D-Ribose 5-phosphate+++R00855///CDPglycerol phosphoglycerohydrolase CDP-glycerol + H2O <=> CMP + sn-Glycerol 3-phosphate","GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0047631///ADP-ribose diphosphatase activity+++GO:0047734///CDP-glycerol diphosphatase activity","GO:0034656///nucleobase-containing small molecule catabolic process","transmembrane protein 220","[TM220_HUMAN|Reviewed]RecName: Full=Transmembrane protein 220;+++[J3KSH5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 220 {ECO:0000313|Ensembl:ENSP00000462490}; Flags: Fragment;+++[J3KSZ3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 220 {ECO:0000313|Ensembl:ENSP00000462723};+++[J3QRF6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 220 {ECO:0000313|Ensembl:ENSP00000464189}; Flags: Fragment;"]
[388552,"'BLOC1S3'",194,196,207,199,null,"H00166///Hermansky-Pudlak syndrome (HPS)",null,null,"GO:0005829///cytosol+++GO:0031083///BLOC-1 complex+++GO:1904115///axon cytoplasm+++GO:0030133///transport vesicle+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity+++GO:0003674///molecular_function","GO:0032816///positive regulation of natural killer cell activation+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0008089///anterograde axonal transport+++GO:0032438///melanosome organization+++GO:0071806///protein transmembrane transport+++GO:0007596///blood coagulation+++GO:0032402///melanosome transport+++GO:0001654///eye development+++GO:0030168///platelet activation+++GO:0048490///anterograde synaptic vesicle transport+++GO:0042493///response to drug+++GO:0035646///endosome to melanosome transport+++GO:0060155///platelet dense granule organization+++GO:0031175///neuron projection development+++GO:0033299///secretion of lysosomal enzymes","biogenesis of lysosomal organelles complex 1 subunit 3","[BL1S3_HUMAN|Reviewed]RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 3; Short=BLOC-1 subunit 3;+++[K7EN58_HUMAN|Unreviewed]SubName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 3 {ECO:0000313|Ensembl:ENSP00000466798}; Flags: Fragment;"]
[388677,"'NOTCH2NLA'",176.55,241.6,237.24,218.463333333333,"05224///Breast cancer+++04330///Notch signaling pathway+++04320///Dorso-ventral axis formation+++05200///Pathways in cancer+++05165///Human papillomavirus infection+++04919///Thyroid hormone signaling pathway+++04658///Th1 and Th2 cell differentiation+++01522///Endocrine resistance+++05206///MicroRNAs in cancer","H00551///Alagille syndrome+++H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding","GO:0030154///cell differentiation+++GO:0021987///cerebral cortex development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway","notch 2 N-terminal like A","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NC_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[388962,"'BOLA3'",259,288,240,262.333333333333,null,"H01894///Multiple mitochondrial dysfunctions syndrome",null,null,"GO:0005739///mitochondrion","GO:0003674///molecular_function+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008150///biological_process+++GO:0006357///regulation of transcription by RNA polymerase II","bolA family member 3","[BOLA3_HUMAN|Reviewed]RecName: Full=BolA-like protein 3 {ECO:0000305};+++[Q8N338_HUMAN|Unreviewed]SubName: Full=BOLA3 protein {ECO:0000313|EMBL:AAH28282.1}; Flags: Fragment;"]
[389177,"'TMEM212'",300.68,410.81,307.71,339.733333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 212","[TM212_HUMAN|Reviewed]RecName: Full=Transmembrane protein 212;+++[H7C098_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 212 {ECO:0000313|Ensembl:ENSP00000393684}; Flags: Fragment;+++[H7C390_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 212 {ECO:0000313|Ensembl:ENSP00000410327}; Flags: Fragment;"]
[389524,"'GTF2IRD2B'",337.08,384.6,377.59,366.423333333333,"04145///Phagosome+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04670///Leukocyte transendothelial migration+++05140///Leishmaniasis+++03022///Basal transcription factors+++04380///Osteoclast differentiation+++04062///Chemokine signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++05418///Fluid shear stress and atherosclerosis+++05168///Herpes simplex infection+++04022///cGMP-PKG signaling pathway","H01167///Gluconobacter infection+++H00098///Chronic granulomatous disease+++H01439///Williams-Beuren syndrome",null,null,"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0014883///transition between fast and slow fiber","GTF2I repeat domain containing 2B","[GTD2B_HUMAN|Reviewed]RecName: Full=General transcription factor II-I repeat domain-containing protein 2B; Short=GTF2I repeat domain-containing protein 2B; AltName: Full=Transcription factor GTF2IRD2-beta;+++[A0A087WW90_HUMAN|Unreviewed]SubName: Full=General transcription factor II-I repeat domain-containing protein 2B {ECO:0000313|Ensembl:ENSP00000480037};+++[A0A0D9SF80_HUMAN|Unreviewed]SubName: Full=General transcription factor II-I repeat domain-containing protein 2A {ECO:0000313|Ensembl:ENSP00000486581}; SubName: Full=General transcription factor II-I repeat domain-containing protein 2B {ECO:0000313|Ensembl:ENSP00000486360};+++[Q86Y00_HUMAN|Unreviewed]SubName: Full=GTF2IRD2B protein {ECO:0000313|EMBL:AAH48252.1}; Flags: Fragment;"]
[389792,"'IER5L'",953,715,789,819,{"$nulls":7},"immediate early response 5 like","[IER5L_HUMAN|Reviewed]RecName: Full=Immediate early response gene 5-like protein;"]
[389816,"'LRRC26'",68,71,47,62,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0005886///plasma membrane","GO:0099104///potassium channel activator activity+++GO:0044325///ion channel binding+++GO:0005249///voltage-gated potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:0005515///protein binding","GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity","leucine rich repeat containing 26","[LRC26_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 26; AltName: Full=BK channel auxiliary gamma subunit LRRC26; AltName: Full=Cytokeratin-associated protein in cancer; Flags: Precursor;"]
[390937,"'LOC390937'",1,2,0,1,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated","ETS domain-containing transcription factor ERF","[A0A1W2PQ73_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000491574};"]
[3915,"'LAMC1'",8964,7934,7606,8168,"05146///Amoebiasis+++04151///PI3K-Akt signaling pathway+++05020///Prion diseases+++05222///Small cell lung cancer+++05200///Pathways in cancer+++05165///Human papillomavirus infection+++04510///Focal adhesion+++05145///Toxoplasmosis+++04512///ECM-receptor interaction",{"$nulls":3},"GO:0005615///extracellular space+++GO:0043260///laminin-11 complex+++GO:0031012///extracellular matrix+++GO:0070062///extracellular exosome+++GO:0043259///laminin-10 complex+++GO:0005606///laminin-1 complex+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen","GO:0005201///extracellular matrix structural constituent","GO:0022617///extracellular matrix disassembly+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0065003///protein-containing complex assembly+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0043687///post-translational protein modification+++GO:0030198///extracellular matrix organization+++GO:0016477///cell migration+++GO:0044267///cellular protein metabolic process+++GO:0007155///cell adhesion+++GO:0007492///endoderm development+++GO:0031581///hemidesmosome assembly","laminin subunit gamma 1","[LAMC1_HUMAN|Reviewed]RecName: Full=Laminin subunit gamma-1; AltName: Full=Laminin B2 chain; AltName: Full=Laminin-1 subunit gamma; AltName: Full=Laminin-10 subunit gamma; AltName: Full=Laminin-11 subunit gamma; AltName: Full=Laminin-2 subunit gamma; AltName: Full=Laminin-3 subunit gamma; AltName: Full=Laminin-4 subunit gamma; AltName: Full=Laminin-6 subunit gamma; AltName: Full=Laminin-7 subunit gamma; AltName: Full=Laminin-8 subunit gamma; AltName: Full=Laminin-9 subunit gamma; AltName: Full=S-laminin subunit gamma; Short=S-LAM gamma; Flags: Precursor;+++[A0A024R972_HUMAN|Unreviewed]SubName: Full=Laminin, gamma 1 (Formerly LAMB2), isoform CRA_a {ECO:0000313|EMBL:EAW91145.1};+++[Q6NVY8_HUMAN|Unreviewed]SubName: Full=LAMC1 protein {ECO:0000313|EMBL:AAH67813.1};+++[R4GNC7_HUMAN|Unreviewed]SubName: Full=Laminin subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000473583}; Flags: Fragment;"]
[3921,"'RPSA'",7938.53,7737.37,7384.04,7686.64666666667,"03010///Ribosome","H01435///Congenital asplenia","M00177///Ribosome, eukaryotes",null,"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0062023///collagen-containing extracellular matrix+++GO:0005840///ribosome+++GO:0005604///basement membrane+++GO:0022627///cytosolic small ribosomal subunit+++GO:0009986///cell surface+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0015935///small ribosomal subunit+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0008289///lipid binding+++GO:0003735///structural constituent of ribosome+++GO:0005102///signaling receptor binding+++GO:0003723///RNA binding+++GO:0001530///lipopolysaccharide binding+++GO:0043022///ribosome binding+++GO:0070891///lipoteichoic acid binding+++GO:0071723///lipopeptide binding+++GO:0043236///laminin binding+++GO:0005515///protein binding+++GO:0005055///laminin receptor activity+++GO:0001618///virus receptor activity","GO:0098609///cell-cell adhesion+++GO:0007155///cell adhesion+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006413///translational initiation+++GO:0030855///epithelial cell differentiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0044130///negative regulation of growth of symbiont in host+++GO:0071223///cellular response to lipoteichoic acid+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045919///positive regulation of cytolysis+++GO:0043032///positive regulation of macrophage activation+++GO:0002376///immune system process+++GO:0060265///positive regulation of respiratory burst involved in inflammatory response+++GO:0042742///defense response to bacterium+++GO:0032490///detection of molecule of bacterial origin+++GO:0071222///cellular response to lipopolysaccharide+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0008228///opsonization+++GO:0033036///macromolecule localization+++GO:0050830///defense response to Gram-positive bacterium+++GO:0046718///viral entry into host cell+++GO:0032496///response to lipopolysaccharide+++GO:0002281///macrophage activation involved in immune response+++GO:0050829///defense response to Gram-negative bacterium+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0006968///cellular defense response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0042535///positive regulation of tumor necrosis factor biosynthetic process+++GO:0000461///endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0045087///innate immune response+++GO:0006407///rRNA export from nucleus+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0002232///leukocyte chemotaxis involved in inflammatory response+++GO:0016032///viral process+++GO:0006412///translation+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0002224///toll-like receptor signaling pathway+++GO:0015920///lipopolysaccharide transport+++GO:0032722///positive regulation of chemokine production+++GO:0000028///ribosomal small subunit assembly+++GO:0006869///lipid transport+++GO:0019221///cytokine-mediated signaling pathway+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0006953///acute-phase response","ribosomal protein SA","[RSSA_HUMAN|Reviewed]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Colon carcinoma laminin-binding protein; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Multidrug resistance-associated protein MGr1-Ag; AltName: Full=NEM/1CHD4; AltName: Full=Small ribosomal subunit protein uS2 {ECO:0000303|PubMed:24524803};+++[A0A024R2P0_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein SA {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000256|HAMAP-Rule:MF_03016};+++[A0A0C4DG17_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein SA {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000256|HAMAP-Rule:MF_03016};+++[C9J9K3_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein SA {ECO:0000313|Ensembl:ENSP00000410848}; Flags: Fragment;+++[F8WD59_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein SA {ECO:0000313|Ensembl:ENSP00000396716}; Flags: Fragment;+++[Q96RS2_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein SA {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000256|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000256|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000256|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000256|HAMAP-Rule:MF_03016};"]
[3956,"'LGALS1'",4027,2921,3806,3584.66666666667,"00750///Vitamin B6 metabolism+++01100///Metabolic pathways",null,null,"R02494///pyridoxamine-5'-phosphate phosphohydrolase Pyridoxamine + Orthophosphate <=> Pyridoxamine phosphate + H2O+++R00173///pyridoxal-5'-phosphate phosphohydrolase Pyridoxal phosphate + H2O <=> Pyridoxal + Orthophosphate+++R01911///pyridoxine-5'-phosphate phosphohydrolase Pyridoxine + Orthophosphate <=> Pyridoxine phosphate + H2O","GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0062023///collagen-containing extracellular matrix+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005622///intracellular","GO:0043236///laminin binding+++GO:0003723///RNA binding+++GO:0030246///carbohydrate binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0030395///lactose binding","GO:0010977///negative regulation of neuron projection development+++GO:0045445///myoblast differentiation+++GO:2001200///positive regulation of dendritic cell differentiation+++GO:0044267///cellular protein metabolic process+++GO:0071333///cellular response to glucose stimulus+++GO:0043687///post-translational protein modification+++GO:0006915///apoptotic process+++GO:0031295///T cell costimulation+++GO:0035900///response to isolation stress+++GO:0034120///positive regulation of erythrocyte aggregation+++GO:0048678///response to axon injury+++GO:0042493///response to drug+++GO:0071407///cellular response to organic cyclic compound+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046598///positive regulation of viral entry into host cell+++GO:0002317///plasma cell differentiation","galectin 1","[LEG1_HUMAN|Reviewed]RecName: Full=Galectin-1; Short=Gal-1; AltName: Full=14 kDa laminin-binding protein; Short=HLBP14; AltName: Full=14 kDa lectin; AltName: Full=Beta-galactoside-binding lectin L-14-I; AltName: Full=Galaptin; AltName: Full=HBL; AltName: Full=HPL; AltName: Full=Lactose-binding lectin 1; AltName: Full=Lectin galactoside-binding soluble 1; AltName: Full=Putative MAPK-activating protein PM12; AltName: Full=S-Lac lectin 1;+++[A0A0B6XK00_HUMAN|Unreviewed]SubName: Full=Lectin, galactoside-binding, soluble, 1 {ECO:0000313|EMBL:CEF49527.1}; Flags: Fragment;+++[F8WCQ5_HUMAN|Unreviewed]SubName: Full=Galectin-1 {ECO:0000313|Ensembl:ENSP00000404414};+++[F8WEI7_HUMAN|Unreviewed]SubName: Full=Galectin-1 {ECO:0000313|Ensembl:ENSP00000388296};"]
[3965,"'LGALS9'",19,16,27,20.6666666666667,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005534///galactose binding+++GO:0030246///carbohydrate binding+++GO:0019899///enzyme binding+++GO:0048030///disaccharide binding","GO:0032673///regulation of interleukin-4 production+++GO:0071346///cellular response to interferon-gamma+++GO:0007565///female pregnancy+++GO:1902715///positive regulation of interferon-gamma secretion+++GO:2001184///positive regulation of interleukin-12 secretion+++GO:2000563///positive regulation of CD4-positive, alpha-beta T cell proliferation+++GO:1900744///regulation of p38MAPK cascade+++GO:1904469///positive regulation of tumor necrosis factor secretion+++GO:0070371///ERK1 and ERK2 cascade+++GO:0006954///inflammatory response+++GO:0032753///positive regulation of interleukin-4 production+++GO:2000778///positive regulation of interleukin-6 secretion+++GO:2001200///positive regulation of dendritic cell differentiation+++GO:0032834///positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0038066///p38MAPK cascade+++GO:0006935///chemotaxis+++GO:0046598///positive regulation of viral entry into host cell+++GO:2001269///positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0032496///response to lipopolysaccharide+++GO:2000667///positive regulation of interleukin-13 secretion+++GO:0070241///positive regulation of activated T cell autonomous cell death+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0097029///mature conventional dendritic cell differentiation+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032682///negative regulation of chemokine production+++GO:0070555///response to interleukin-1+++GO:2000670///positive regulation of dendritic cell apoptotic process+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0071636///positive regulation of transforming growth factor beta production+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0034134///toll-like receptor 2 signaling pathway+++GO:2000484///positive regulation of interleukin-8 secretion+++GO:0043305///negative regulation of mast cell degranulation+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression+++GO:2001181///positive regulation of interleukin-10 secretion+++GO:2000510///positive regulation of dendritic cell chemotaxis+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0002519///natural killer cell tolerance induction+++GO:0002376///immune system process+++GO:0032674///regulation of interleukin-5 production+++GO:0060135///maternal process involved in female pregnancy+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:2001190///positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell","galectin 9","[LEG9_HUMAN|Reviewed]RecName: Full=Galectin-9; Short=Gal-9; AltName: Full=Ecalectin; AltName: Full=Tumor antigen HOM-HD-21;+++[A0A024QZ02_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};+++[A0A024QZ55_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};+++[J3KS82_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[J3KSA0_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[J3QKK6_HUMAN|Unreviewed]SubName: Full=Galectin-9 {ECO:0000313|Ensembl:ENSP00000463125};+++[J3QS92_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[K7EPS0_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;"]
[3983,"'ABLIM1'",5632,5013,4321,4988.66666666667,"04360///Axon guidance",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium","GO:0051015///actin filament binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003779///actin binding","GO:0030032///lamellipodium assembly+++GO:0007010///cytoskeleton organization+++GO:0009887///animal organ morphogenesis+++GO:0060271///cilium assembly+++GO:0007601///visual perception","actin binding LIM protein 1","[ABLM1_HUMAN|Reviewed]RecName: Full=Actin-binding LIM protein 1; Short=abLIM-1; AltName: Full=Actin-binding LIM protein family member 1; AltName: Full=Actin-binding double zinc finger protein; AltName: Full=LIMAB1; AltName: Full=Limatin;+++[A0A0A0MRL6_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 1 {ECO:0000313|Ensembl:ENSP00000358256};+++[B3KSG3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36152 fis, clone TESTI2025403, highly similar to Actin-binding LIM protein 1 {ECO:0000313|EMBL:BAG52725.1};+++[B4DQA3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58603, highly similar to Actin-binding LIM protein 1 {ECO:0000313|EMBL:BAG60865.1};+++[F6XFR5_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 1 {ECO:0000313|Ensembl:ENSP00000400934}; Flags: Fragment;+++[F8W8M4_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 1 {ECO:0000313|Ensembl:ENSP00000433629};+++[H0Y7N6_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 1 {ECO:0000313|Ensembl:ENSP00000414154}; Flags: Fragment;+++[J3QSX6_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 1 {ECO:0000313|Ensembl:ENSP00000358270};"]
[399665,"'FAM102A'",2519,2943,2535,2665.66666666667,"01100///Metabolic pathways+++04140///Autophagy - animal+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis+++00510///N-Glycan biosynthesis+++04137///Mitophagy - animal","H00118///Congenital disorders of glycosylation (CDG) type I",null,"R01009///GDPmannose:dolichyl-phosphate O-beta-D-mannosyltransferase GDP-mannose + Dolichyl phosphate <=> GDP + Dolichyl phosphate D-mannose+++R05916///UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143",null,"GO:0005515///protein binding",null,"family with sequence similarity 102 member A","[F102A_HUMAN|Reviewed]RecName: Full=Protein FAM102A; AltName: Full=Early estrogen-induced gene 1 protein;"]
[4004,"'LMO1'",87,130,81,99.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0046013///regulation of T cell homeostatic proliferation","LIM domain only 1","[RBTN1_HUMAN|Reviewed]RecName: Full=Rhombotin-1; AltName: Full=Cysteine-rich protein TTG-1; AltName: Full=LIM domain only protein 1; Short=LMO-1; AltName: Full=T-cell translocation protein 1;+++[E9PK83_HUMAN|Unreviewed]SubName: Full=Rhombotin-1 {ECO:0000313|Ensembl:ENSP00000435456};+++[Q4VBC4_HUMAN|Unreviewed]SubName: Full=LMO1 protein {ECO:0000313|EMBL:AAH96058.1};+++[Q9H4D3_HUMAN|Unreviewed]SubName: Full=LIM domain only 1 protein {ECO:0000313|EMBL:CAC14573.1}; Flags: Fragment;"]
[400658,"'C18orf65'",12,9,1,7.33333333333333,{"$nulls":7},"chromosome 18 open reading frame 65","[CR065_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C18orf65 {ECO:0000305};"]
[401036,"'ASB18'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0031625///ubiquitin protein ligase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0035556///intracellular signal transduction+++GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination","ankyrin repeat and SOCS box containing 18","[ASB18_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 18; Short=ASB-18;+++[C9JFL4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 18 {ECO:0000313|Ensembl:ENSP00000410021}; Flags: Fragment;+++[H7C3E8_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 18 {ECO:0000313|Ensembl:ENSP00000411434}; Flags: Fragment;"]
[4012,"'LNPEP'",291,249,279,273,"04614///Renin-angiotensin system",{"$nulls":3},"GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005576///extracellular region+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0031905///early endosome lumen+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008270///zinc ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding","GO:0043171///peptide catabolic process+++GO:0000209///protein polyubiquitination+++GO:0030163///protein catabolic process+++GO:0006508///proteolysis+++GO:0060395///SMAD protein signal transduction+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0002480///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent+++GO:0007565///female pregnancy+++GO:0007267///cell-cell signaling","leucyl and cystinyl aminopeptidase","[LCAP_HUMAN|Reviewed]RecName: Full=Leucyl-cystinyl aminopeptidase; Short=Cystinyl aminopeptidase; EC=3.4.11.3; AltName: Full=Insulin-regulated membrane aminopeptidase; AltName: Full=Insulin-responsive aminopeptidase; Short=IRAP; AltName: Full=Oxytocinase; Short=OTase; AltName: Full=Placental leucine aminopeptidase; Short=P-LAP; Contains: RecName: Full=Leucyl-cystinyl aminopeptidase, pregnancy serum form;"]
[401478,"'LOC401478'",2,4,1,2.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003964///RNA-directed DNA polymerase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006351///transcription, DNA-templated","uncharacterized LOC401478","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[ESRG_HUMAN|diamond]RecName: Full=Embryonic stem cell-related gene protein; Short=hES cell-related gene protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[402665,"'IGLON5'",61,70,58,63,{"$nulls":4},"GO:0005576///extracellular region",null,null,"IgLON family member 5","[IGLO5_HUMAN|Reviewed]RecName: Full=IgLON family member 5; Flags: Precursor;"]
[403312,"'LOC403312'",0,0,1,0.333333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"putative uncharacterized protein MGC39545","[YK038_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein MGC39545;"]
[404217,"'CTXN1'",3865,3038,3311,3404.66666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane","GO:0003700///DNA-binding transcription factor activity","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006383///transcription by RNA polymerase III+++GO:0009301///snRNA transcription","cortexin 1","[CTXN1_HUMAN|Reviewed]RecName: Full=Cortexin-1;"]
[405754,"'ERVFRD-1'",20,23,22,21.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane",null,"GO:0006949///syncytium formation+++GO:0000768///syncytium formation by plasma membrane fusion","endogenous retrovirus group FRD member 1, envelope","[SYCY2_HUMAN|Reviewed]RecName: Full=Syncytin-2; AltName: Full=Endogenous retrovirus group FRD member 1; AltName: Full=Envelope polyprotein; AltName: Full=HERV-FRD; AltName: Full=HERV-FRD_6p24.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[4074,"'M6PR'",529,436,455,473.333333333333,"04142///Lysosome+++04145///Phagosome",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0032588///trans-Golgi network membrane+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0030133///transport vesicle+++GO:0030904///retromer complex+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:1905394///retromer complex binding","GO:0006622///protein targeting to lysosome+++GO:0006898///receptor-mediated endocytosis+++GO:0061024///membrane organization+++GO:0008333///endosome to lysosome transport+++GO:0033299///secretion of lysosomal enzymes","mannose-6-phosphate receptor, cation dependent","[MPRD_HUMAN|Reviewed]RecName: Full=Cation-dependent mannose-6-phosphate receptor; Short=CD Man-6-P receptor; Short=CD-MPR; AltName: Full=46 kDa mannose 6-phosphate receptor; Short=MPR 46; Flags: Precursor;+++[F5GX30_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000440488};+++[F5GXE0_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000441030}; Flags: Fragment;+++[F5GXU0_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000440962}; Flags: Fragment;+++[F5H4U1_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000439968}; Flags: Fragment;+++[F5H883_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000442100};+++[H0YF90_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000437595}; Flags: Fragment;+++[H0YFL0_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000439070}; Flags: Fragment;+++[H0YFY9_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000441040}; Flags: Fragment;+++[H0YGE9_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000442983}; Flags: Fragment;+++[H0YGT2_HUMAN|Unreviewed]SubName: Full=Cation-dependent mannose-6-phosphate receptor {ECO:0000313|Ensembl:ENSP00000444684}; Flags: Fragment;+++[Q6I9U3_HUMAN|Unreviewed]SubName: Full=M6PR protein {ECO:0000313|EMBL:CAG33693.1};"]
[409,"'ARRB2'",305,316,281,300.666666666667,"04928///Parathyroid hormone synthesis, secretion and action+++04740///Olfactory transduction+++04010///MAPK signaling pathway+++04340///Hedgehog signaling pathway+++04926///Relaxin signaling pathway+++05032///Morphine addiction+++04062///Chemokine signaling pathway+++04144///Endocytosis",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0043197///dendritic spine+++GO:0045211///postsynaptic membrane+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0014069///postsynaptic density+++GO:0005768///endosome+++GO:0016323///basolateral plasma membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit","GO:0032947///protein-containing complex scaffold activity+++GO:0031762///follicle-stimulating hormone receptor binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0031859///platelet activating factor receptor binding+++GO:0031826///type 2A serotonin receptor binding+++GO:0005515///protein binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0042802///identical protein binding+++GO:0071889///14-3-3 protein binding+++GO:0031702///type 1 angiotensin receptor binding+++GO:0005102///signaling receptor binding+++GO:0031701///angiotensin receptor binding+++GO:0043422///protein kinase B binding+++GO:0031748///D1 dopamine receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0019899///enzyme binding+++GO:0001664///G protein-coupled receptor binding+++GO:1990763///arrestin family protein binding+++GO:0031691///alpha-1A adrenergic receptor binding+++GO:0031692///alpha-1B adrenergic receptor binding","GO:0032715///negative regulation of interleukin-6 production+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0001934///positive regulation of protein phosphorylation+++GO:0030168///platelet activation+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0016579///protein deubiquitination+++GO:0002032///desensitization of G protein-coupled receptor signaling pathway by arrestin+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:0016567///protein ubiquitination+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0007212///dopamine receptor signaling pathway+++GO:0031398///positive regulation of protein ubiquitination+++GO:0010628///positive regulation of gene expression+++GO:0042699///follicle-stimulating hormone signaling pathway+++GO:0032695///negative regulation of interleukin-12 production+++GO:0009968///negative regulation of signal transduction+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0006366///transcription by RNA polymerase II+++GO:0031623///receptor internalization+++GO:0002031///G protein-coupled receptor internalization+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0031397///negative regulation of protein ubiquitination+++GO:0061024///membrane organization+++GO:0060326///cell chemotaxis+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:1904037///positive regulation of epithelial cell apoptotic process+++GO:0007165///signal transduction+++GO:0034260///negative regulation of GTPase activity+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0006897///endocytosis+++GO:0002092///positive regulation of receptor internalization+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:0015031///protein transport+++GO:0032226///positive regulation of synaptic transmission, dopaminergic+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060079///excitatory postsynaptic potential+++GO:0001932///regulation of protein phosphorylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:0051928///positive regulation of calcium ion transport+++GO:0007628///adult walking behavior+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0007420///brain development","arrestin beta 2","[ARRB2_HUMAN|Reviewed]RecName: Full=Beta-arrestin-2; AltName: Full=Arrestin beta-2; AltName: Full=Non-visual arrestin-3 {ECO:0000303|PubMed:23886940};+++[I3L0V6_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-2 {ECO:0000313|Ensembl:ENSP00000458371};+++[I3L1M6_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-2 {ECO:0000313|Ensembl:ENSP00000458946};+++[I3L412_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-2 {ECO:0000313|Ensembl:ENSP00000460879}; Flags: Fragment;+++[K7EL17_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-2 {ECO:0000313|Ensembl:ENSP00000465877}; Flags: Fragment;+++[K7ENA6_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-2 {ECO:0000313|Ensembl:ENSP00000466857};+++[L8ECB1_HUMAN|Unreviewed]SubName: Full=Alternative protein ARRB2 {ECO:0000313|EMBL:CCQ43257.1};+++[Q59EM5_HUMAN|Unreviewed]SubName: Full=Arrestin beta 2 isoform 1 variant {ECO:0000313|EMBL:BAD93023.1}; Flags: Fragment;+++[Q68DZ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58316, highly similar to Beta-arrestin-2 {ECO:0000313|EMBL:BAG59581.1};"]
[4123,"'MAN2C1'",872,1048,1017,979,"00511///Other glycan degradation","H01861///Chromosome 15q24 microdeletion syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0004559///alpha-mannosidase activity+++GO:0003824///catalytic activity+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding","GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0009313///oligosaccharide catabolic process+++GO:0006013///mannose metabolic process","mannosidase alpha class 2C member 1","[MA2C1_HUMAN|Reviewed]RecName: Full=Alpha-mannosidase 2C1; EC=3.2.1.24 {ECO:0000269|PubMed:16848760}; AltName: Full=Alpha mannosidase 6A8B; AltName: Full=Alpha-D-mannoside mannohydrolase; AltName: Full=Mannosidase alpha class 2C member 1;+++[A0A0C4DGU9_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000479988};+++[A0A140VJN9_HUMAN|Unreviewed]RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199}; EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};+++[B4DH23_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000390738}; SubName: Full=cDNA FLJ57925, highly similar to Alpha-mannosidase 2C1 {ECO:0000313|EMBL:BAG57984.1};+++[H3BMJ3_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000454406};+++[H3BQH9_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000455788}; Flags: Fragment;+++[H3BQJ2_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000455803};+++[H3BRI3_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000456257}; Flags: Fragment;+++[H3BRV3_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000456419};+++[H3BSE5_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000456667}; Flags: Fragment;+++[H3BUW3_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2C1 {ECO:0000313|Ensembl:ENSP00000457833}; Flags: Fragment;"]
[414060,"'TBC1D3C'",22.27,16.04,0,12.77,"05132///Salmonella infection+++04060///Cytokine-cytokine receptor interaction+++05323///Rheumatoid arthritis+++05163///Human cytomegalovirus infection+++04062///Chemokine signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++04620///Toll-like receptor signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3C","[TBC3A_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3; AltName: Full=Prostate cancer gene 17 protein; AltName: Full=Protein TRE17-alpha; AltName: Full=Rab GTPase-activating protein PRC17;+++[TBC3C_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3C;+++[A0A0G2JLM6_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3B {ECO:0000313|Ensembl:ENSP00000478775};"]
[415,"'ARSE'",41,36,18,31.6666666666667,null,"H01194///X-linked chondrodysplasia punctata",null,null,"GO:0016020///membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005795///Golgi stack","GO:0004065///arylsulfatase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0046872///metal ion binding","GO:0001501///skeletal system development","arylsulfatase E","[ARSE_HUMAN|Reviewed]RecName: Full=Arylsulfatase E; Short=ASE; EC=3.1.6.-; Flags: Precursor;+++[A1L484_HUMAN|Unreviewed]SubName: Full=Arylsulfatase E (Chondrodysplasia punctata 1) {ECO:0000313|EMBL:AAI30439.1};+++[B7Z1M0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50116, highly similar to Arylsulfatase E {ECO:0000313|EMBL:BAH11556.1};+++[B7Z6V4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50239, highly similar to Arylsulfatase E {ECO:0000313|EMBL:BAH13390.1};+++[C9J5G7_HUMAN|Unreviewed]SubName: Full=Arylsulfatase E {ECO:0000313|Ensembl:ENSP00000406528}; Flags: Fragment;+++[F5GYY5_HUMAN|Unreviewed]SubName: Full=Arylsulfatase E {ECO:0000313|Ensembl:ENSP00000441417};+++[F5H324_HUMAN|Unreviewed]SubName: Full=Arylsulfatase E {ECO:0000313|Ensembl:ENSP00000438198};"]
[4170,"'MCL1'",2161,1653,1864,1892.66666666667,"04151///PI3K-Akt signaling pathway+++04630///Jak-STAT signaling pathway+++05206///MicroRNAs in cancer+++04210///Apoptosis",{"$nulls":3},"GO:0097136///Bcl-2 family protein complex+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0016459///myosin complex+++GO:0005737///cytoplasm","GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0051434///BH3 domain binding+++GO:0042803///protein homodimerization activity","GO:0019221///cytokine-mediated signaling pathway+++GO:0030154///cell differentiation+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0019725///cellular homeostasis+++GO:2000811///negative regulation of anoikis+++GO:0034097///response to cytokine+++GO:0006915///apoptotic process+++GO:1903378///positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0042981///regulation of apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0007275///multicellular organism development+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0001709///cell fate determination+++GO:0071806///protein transmembrane transport+++GO:0010507///negative regulation of autophagy+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0043066///negative regulation of apoptotic process","MCL1, BCL2 family apoptosis regulator","[MCL1_HUMAN|Reviewed]RecName: Full=Induced myeloid leukemia cell differentiation protein Mcl-1; AltName: Full=Bcl-2-like protein 3; Short=Bcl2-L-3; AltName: Full=Bcl-2-related protein EAT/mcl1; AltName: Full=mcl1/EAT;+++[A0A087WT64_HUMAN|Unreviewed]SubName: Full=Induced myeloid leukemia cell differentiation protein Mcl-1 {ECO:0000313|Ensembl:ENSP00000477624};+++[C8YZ26_HUMAN|Unreviewed]SubName: Full=Myeloid cell leukemia ES variant {ECO:0000313|EMBL:ACV83304.1};+++[Q03399_HUMAN|Unreviewed]SubName: Full=Myosin light chain 1 {ECO:0000313|EMBL:CAA36256.1};"]
[4199,"'ME1'",110,132,127,123,"00710///Carbon fixation in photosynthetic organisms+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways",null,"M00172///C4-dicarboxylic acid cycle, NADP - malic enzyme type+++M00169///CAM (Crassulacean acid metabolism), light","R00216///(S)-Malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating)   (S)-Malate + NADP+ <=> Pyruvate + CO2 + NADPH + H+","GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0051287///NAD binding+++GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0050661///NADP binding+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0030145///manganese ion binding+++GO:0043531///ADP binding+++GO:0004470///malic enzyme activity+++GO:0009055///electron transfer activity","GO:0006108///malate metabolic process+++GO:0051262///protein tetramerization+++GO:0019216///regulation of lipid metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006741///NADP biosynthetic process+++GO:0009743///response to carbohydrate+++GO:0009725///response to hormone+++GO:1902031///regulation of NADP metabolic process+++GO:0006090///pyruvate metabolic process","malic enzyme 1","[MAOX_HUMAN|Reviewed]RecName: Full=NADP-dependent malic enzyme; Short=NADP-ME; EC=1.1.1.40; AltName: Full=Malic enzyme 1;"]
[4216,"'MAP3K4'",282,258,241,260.333333333333,"04624///Toll and Imd signaling pathway+++04013///MAPK signaling pathway - fly+++04010///MAPK signaling pathway+++04912///GnRH signaling pathway",null,"M00689///MAPK (p38) signaling+++M00688///MAPK (JNK) signaling",null,"GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0004709///MAP kinase kinase kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity","GO:0016310///phosphorylation+++GO:0000165///MAPK cascade+++GO:0043507///positive regulation of JUN kinase activity+++GO:0032147///activation of protein kinase activity+++GO:0010468///regulation of gene expression+++GO:0019100///male germ-line sex determination+++GO:0006468///protein phosphorylation+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0035556///intracellular signal transduction+++GO:0000186///activation of MAPKK activity+++GO:1904355///positive regulation of telomere capping+++GO:0001890///placenta development+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:0023014///signal transduction by protein phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0010225///response to UV-C+++GO:0060718///chorionic trophoblast cell differentiation","mitogen-activated protein kinase kinase kinase 4","[M3K4_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase 4; EC=2.7.11.25; AltName: Full=MAP three kinase 1; AltName: Full=MAPK/ERK kinase kinase 4; Short=MEK kinase 4; Short=MEKK 4;+++[F5H1X6_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000446303};+++[F5H2S6_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000439377};+++[F5H4R1_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000445018};+++[F5H534_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000390508}; Flags: Fragment;+++[F5H538_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000355887};+++[J3KNB8_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000297332};+++[Q9P1M2_HUMAN|Unreviewed]SubName: Full=PRO0412 {ECO:0000313|EMBL:AAF71029.1};"]
[4249,"'MGAT5'",638,768,663,689.666666666667,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis",null,"M00075///N-glycan biosynthesis, complex type","R07622///UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G10818+++R05991///UDP-N-acetyl-D-glucosamine + G00020 <=> UDP + G00021","GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus","GO:0008375///acetylglucosaminyltransferase activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0030145///manganese ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0030144///alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity","GO:0018279///protein N-linked glycosylation via asparagine+++GO:0030335///positive regulation of cell migration+++GO:0006487///protein N-linked glycosylation+++GO:1904894///positive regulation of STAT cascade+++GO:0006486///protein glycosylation+++GO:1903614///negative regulation of protein tyrosine phosphatase activity","alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase","[MGT5A_HUMAN|Reviewed]RecName: Full=Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; EC=2.4.1.155; AltName: Full=Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; AltName: Full=GlcNAc-T V; Short=GNT-V; AltName: Full=Mannoside acetylglucosaminyltransferase 5; AltName: Full=N-acetylglucosaminyl-transferase V;+++[Q53SM9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MGAT5 {ECO:0000313|EMBL:AAY14791.1}; Flags: Fragment;+++[Q53SV8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MGAT5 {ECO:0000313|EMBL:AAX93248.1}; Flags: Fragment;+++[Q53SZ9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MGAT5 {ECO:0000313|EMBL:AAY14747.1}; Flags: Fragment;"]
[4281,"'MID1'",802,777,730,769.666666666667,"04120///Ubiquitin mediated proteolysis","H00583///Opitz-GBBB syndrome",null,"R02480///Cytochrome c apocytochrome-c-lyase Cytochrome c <=> Apocytochrome c + Heme","GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0005874///microtubule+++GO:0016021///integral component of membrane+++GO:0015630///microtubule cytoskeleton+++GO:0005875///microtubule associated complex+++GO:0005737///cytoplasm+++GO:0005881///cytoplasmic microtubule","GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008017///microtubule binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051219///phosphoprotein binding","GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0000226///microtubule cytoskeleton organization+++GO:0035372///protein localization to microtubule+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007389///pattern specification process","midline 1","[TRI18_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Midline-1; EC=2.3.2.27; AltName: Full=Midin; AltName: Full=Putative transcription factor XPRF; AltName: Full=RING finger protein 59; AltName: Full=RING finger protein Midline-1; AltName: Full=RING-type E3 ubiquitin transferase Midline-1 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 18;+++[A0A024RBV4_HUMAN|Unreviewed]SubName: Full=Midline 1 (Opitz/BBB syndrome), isoform CRA_a {ECO:0000313|EMBL:EAW98781.1};+++[A0A087X0X0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000483707};+++[A0A087X255_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000484712};+++[C9J453_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000391154}; Flags: Fragment;+++[C9JZJ7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000387771}; Flags: Fragment;"]
[43,"'ACHE'",27,44,41,37.3333333333333,"00564///Glycerophospholipid metabolism+++04725///Cholinergic synapse",null,null,"R01026///Acetylcholine aectylhydrolase   Acetylcholine + H2O <=> Choline + Acetate","GO:0031594///neuromuscular junction+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005615///extracellular space+++GO:0043083///synaptic cleft+++GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0031225///anchored component of membrane+++GO:0045202///synapse+++GO:0016020///membrane","GO:0043236///laminin binding+++GO:0003990///acetylcholinesterase activity+++GO:0005518///collagen binding+++GO:0017171///serine hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0042166///acetylcholine binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0043621///protein self-association+++GO:0004104///cholinesterase activity+++GO:0042803///protein homodimerization activity+++GO:0001540///amyloid-beta binding","GO:0051262///protein tetramerization+++GO:0009611///response to wounding+++GO:0001507///acetylcholine catabolic process in synaptic cleft+++GO:0008283///cell proliferation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0007155///cell adhesion+++GO:0002076///osteoblast development+++GO:0045212///neurotransmitter receptor biosynthetic process+++GO:0007416///synapse assembly+++GO:0006260///DNA replication+++GO:0006581///acetylcholine catabolic process+++GO:0042136///neurotransmitter biosynthetic process+++GO:0060041///retina development in camera-type eye+++GO:0001919///regulation of receptor recycling+++GO:0042135///neurotransmitter catabolic process+++GO:0007517///muscle organ development+++GO:0007399///nervous system development+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0031623///receptor internalization+++GO:0050714///positive regulation of protein secretion+++GO:0042982///amyloid precursor protein metabolic process+++GO:0032223///negative regulation of synaptic transmission, cholinergic","acetylcholinesterase (Cartwright blood group)","[ACES_HUMAN|Reviewed]RecName: Full=Acetylcholinesterase; Short=AChE; EC=3.1.1.7; Flags: Precursor;+++[A0A166IZM7_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[A0A2S1KLT7_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[C9J2S3_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[C9JD78_HUMAN|Unreviewed]SubName: Full=Acetylcholinesterase {ECO:0000313|Ensembl:ENSP00000396360}; Flags: Fragment;+++[C9JZL6_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[D6W5X8_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};+++[F8WAR7_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};+++[F8WD34_HUMAN|Unreviewed]SubName: Full=Acetylcholinesterase {ECO:0000313|Ensembl:ENSP00000415901};+++[F8WD68_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};+++[Q13697_HUMAN|Unreviewed]SubName: Full=Acetylcholinesterase {ECO:0000313|EMBL:AAA53473.1}; Flags: Fragment;+++[Q6TQD3_HUMAN|Unreviewed]SubName: Full=Acetylcholinesterase {ECO:0000313|Ensembl:ENSP00000400933}; SubName: Full=N-terminal extended acetylcholinesterase {ECO:0000313|EMBL:AAR26654.1}; Flags: Fragment;"]
[4325,"'MMP16'",143,96,113,117.333333333333,"05206///MicroRNAs in cancer+++04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005796///Golgi lumen+++GO:0031012///extracellular matrix","GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008270///zinc ion binding+++GO:0008047///enzyme activator activity+++GO:0008237///metallopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0016787///hydrolase activity","GO:0019538///protein metabolic process+++GO:0035988///chondrocyte proliferation+++GO:0001958///endochondral ossification+++GO:0022617///extracellular matrix disassembly+++GO:0060348///bone development+++GO:0006508///proteolysis+++GO:0016485///protein processing+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0030574///collagen catabolic process+++GO:0043085///positive regulation of catalytic activity+++GO:0097094///craniofacial suture morphogenesis+++GO:0001503///ossification","matrix metallopeptidase 16","[MMP16_HUMAN|Reviewed]RecName: Full=Matrix metalloproteinase-16; Short=MMP-16; EC=3.4.24.-; AltName: Full=MMP-X2; AltName: Full=Membrane-type matrix metalloproteinase 3; Short=MT-MMP 3; Short=MTMMP3; AltName: Full=Membrane-type-3 matrix metalloproteinase; Short=MT3-MMP; Short=MT3MMP; Flags: Precursor;+++[E5RJA7_HUMAN|Unreviewed]RecName: Full=Matrix metalloproteinase {ECO:0000256|RuleBase:RU364080}; EC=3.4.24.- {ECO:0000256|RuleBase:RU364080}; Flags: Fragment;"]
[4343,"'MOV10'",1389,1623,1491,1501,{"$nulls":4},"GO:0000932///P-body+++GO:0005634///nucleus+++GO:0043186///P granule+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule","GO:0016787///hydrolase activity+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0032575///ATP-dependent 5'-3' RNA helicase activity+++GO:0004386///helicase activity","GO:0010628///positive regulation of gene expression+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0031047///gene silencing by RNA+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0010629///negative regulation of gene expression+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0010526///negative regulation of transposition, RNA-mediated+++GO:0035195///gene silencing by miRNA+++GO:0035279///mRNA cleavage involved in gene silencing by miRNA+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0035194///posttranscriptional gene silencing by RNA+++GO:0150011///regulation of neuron projection arborization","Mov10 RISC complex RNA helicase","[MOV10_HUMAN|Reviewed]RecName: Full=Putative helicase MOV-10; EC=3.6.4.13; AltName: Full=Armitage homolog {ECO:0000303|PubMed:17507929}; AltName: Full=Moloney leukemia virus 10 protein;+++[Q5JR04_HUMAN|Unreviewed]SubName: Full=Mov10, Moloney leukemia virus 10, homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW56528.1}; SubName: Full=Putative helicase MOV-10 {ECO:0000313|Ensembl:ENSP00000358658};"]
[440023,"'KRTAP5-6'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0045095///keratin filament",null,"GO:0031424///keratinization","keratin associated protein 5-6","[KRA56_HUMAN|Reviewed]RecName: Full=Keratin-associated protein 5-6; AltName: Full=Keratin-associated protein 5.6; AltName: Full=Ultrahigh sulfur keratin-associated protein 5.6;"]
[440275,"'EIF2AK4'",1014,1001,1022,1012.33333333333,"04141///Protein processing in endoplasmic reticulum+++05160///Hepatitis C+++05162///Measles+++04140///Autophagy - animal+++05164///Influenza A+++04138///Autophagy - yeast+++05168///Herpes simplex infection+++05169///Epstein-Barr virus infection","H01866///Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis+++H01621///Pulmonary arterial hypertension (PAH)",null,null,"GO:0005844///polysome+++GO:0005737///cytoplasm+++GO:0022626///cytosolic ribosome","GO:0004694///eukaryotic translation initiation factor 2alpha kinase activity+++GO:0000049///tRNA binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0061630///ubiquitin protein ligase activity","GO:0045947///negative regulation of translational initiation+++GO:0010998///regulation of translational initiation by eIF2 alpha phosphorylation+++GO:0016032///viral process+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:0007050///cell cycle arrest+++GO:0032057///negative regulation of translational initiation in response to stress+++GO:0046777///protein autophosphorylation+++GO:0002230///positive regulation of defense response to virus by host+++GO:0034198///cellular response to amino acid starvation+++GO:0002250///adaptive immune response+++GO:0034644///cellular response to UV+++GO:0007399///nervous system development+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:0000077///DNA damage checkpoint+++GO:0045665///negative regulation of neuron differentiation+++GO:0007616///long-term memory+++GO:0070417///cellular response to cold+++GO:0006417///regulation of translation+++GO:0071264///positive regulation of translational initiation in response to starvation+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0002376///immune system process+++GO:0060733///regulation of eIF2 alpha phosphorylation by amino acid starvation+++GO:0006446///regulation of translational initiation+++GO:0019081///viral translation+++GO:0036492///eiF2alpha phosphorylation in response to endoplasmic reticulum stress+++GO:1990138///neuron projection extension+++GO:0002286///T cell activation involved in immune response+++GO:0051607///defense response to virus+++GO:0039520///induction by virus of host autophagy+++GO:0060259///regulation of feeding behavior+++GO:1990253///cellular response to leucine starvation+++GO:0007612///learning+++GO:0002821///positive regulation of adaptive immune response+++GO:0016310///phosphorylation+++GO:0044828///negative regulation by host of viral genome replication+++GO:0016567///protein ubiquitination","eukaryotic translation initiation factor 2 alpha kinase 4","[E2AK4_HUMAN|Reviewed]RecName: Full=eIF-2-alpha kinase GCN2 {ECO:0000250|UniProtKB:Q9QZ05}; EC=2.7.11.1 {ECO:0000250|UniProtKB:Q9QZ05}; AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 4 {ECO:0000312|HGNC:HGNC:19687}; AltName: Full=GCN2-like protein;+++[H0YME5_HUMAN|Unreviewed]SubName: Full=eIF-2-alpha kinase GCN2 {ECO:0000313|Ensembl:ENSP00000453575}; Flags: Fragment;+++[H0YND8_HUMAN|Unreviewed]SubName: Full=eIF-2-alpha kinase GCN2 {ECO:0000313|Ensembl:ENSP00000453968};+++[H0YNY9_HUMAN|Unreviewed]SubName: Full=eIF-2-alpha kinase GCN2 {ECO:0000313|Ensembl:ENSP00000454210}; Flags: Fragment;"]
[440590,"'ZYG11A'",2,4,8,4.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031462///Cul2-RING ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:0016567///protein ubiquitination","zyg-11 family member A, cell cycle regulator","[ZY11A_HUMAN|Reviewed]RecName: Full=Protein zyg-11 homolog A;"]
[440804,"'RIMBP3B'",1,0,2,1,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0002177///manchette+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0030156///benzodiazepine receptor binding","GO:0007283///spermatogenesis+++GO:0009566///fertilization+++GO:0007286///spermatid development+++GO:0007274///neuromuscular synaptic transmission+++GO:0030154///cell differentiation","RIMS binding protein 3B","[RIM3B_HUMAN|Reviewed]RecName: Full=RIMS-binding protein 3B; Short=RIM-BP3.B; AltName: Full=RIMS-binding protein 3.2; Short=RIM-BP3.2;"]
[441376,"'AARD'",71,97,73,80.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":5},"GO:0030324///lung development","alanine and arginine rich domain containing protein","[AARD_HUMAN|Reviewed]RecName: Full=Alanine and arginine-rich domain-containing protein;+++[B2RU19_HUMAN|Unreviewed]SubName: Full=Chromosome 8 open reading frame 85 {ECO:0000313|EMBL:AAI40925.1};"]
[441549,"'CDNF'",10,14,7,10.3333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space","GO:0008083///growth factor activity","GO:0031175///neuron projection development+++GO:0010469///regulation of signaling receptor activity","cerebral dopamine neurotrophic factor","[CDNF_HUMAN|Reviewed]RecName: Full=Cerebral dopamine neurotrophic factor; AltName: Full=ARMET-like protein 1; AltName: Full=Conserved dopamine neurotrophic factor; Flags: Precursor;"]
[445577,"'C9orf129'",2.44,0,1.31,1.25,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00243///Hyperkalemic distal renal tubular acidosis (RTA type 4)+++H00265///Hereditary sensory and autonomic neuropathy (HSAN)",null,null,"GO:0005634///nucleus",null,"GO:0045444///fat cell differentiation+++GO:0035357///peroxisome proliferator activated receptor signaling pathway","chromosome 9 open reading frame 129","[CI129_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C9orf129;"]
[4515,"'MTCP1'",8.18,5.61,7.2,6.99666666666667,"04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0000151///ubiquitin ligase complex+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0070531///BRCA1-A complex+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex+++GO:0000152///nuclear ubiquitin ligase complex+++GO:0070552///BRISC complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0008237///metallopeptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0046872///metal ion binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0030234///enzyme regulator activity+++GO:0019901///protein kinase binding+++GO:0031593///polyubiquitin modification-dependent protein binding","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0070536///protein K63-linked deubiquitination+++GO:0010212///response to ionizing radiation+++GO:0007049///cell cycle+++GO:0006302///double-strand break repair+++GO:0051301///cell division+++GO:0045739///positive regulation of DNA repair+++GO:0008283///cell proliferation+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0010165///response to X-ray+++GO:0000422///autophagy of mitochondrion+++GO:0016579///protein deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination","mature T cell proliferation 1","[MTCP1_HUMAN|Reviewed]RecName: Full=Protein p13 MTCP-1; Short=p13MTCP1; AltName: Full=Mature T-cell proliferation-1 type B1; Short=MTCP-1 type B1;"]
[4548,"'MTR'",471,503,516,496.666666666667,"00450///Selenocompound metabolism+++00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00670///One carbon pool by folate+++01110///Biosynthesis of secondary metabolites+++01230///Biosynthesis of amino acids","H01285///Methylcobalamin deficiency type G (cblG)+++H00262///Spina bifida","M00017///Methionine biosynthesis, apartate => homoserine => methionine","R09365///5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase   Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate+++R00946///5-Methyltetrahydrofolate:L-homocysteine S-methyltransferase   5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008168///methyltransferase activity+++GO:0031419///cobalamin binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0008705///methionine synthase activity","GO:0032259///methylation+++GO:0008652///cellular amino acid biosynthetic process+++GO:0071732///cellular response to nitric oxide+++GO:0009235///cobalamin metabolic process+++GO:0031103///axon regeneration+++GO:0048678///response to axon injury+++GO:0044237///cellular metabolic process+++GO:0009086///methionine biosynthetic process+++GO:0007399///nervous system development+++GO:0042558///pteridine-containing compound metabolic process","5-methyltetrahydrofolate-homocysteine methyltransferase","[METH_HUMAN|Reviewed]RecName: Full=Methionine synthase; EC=2.1.1.13; AltName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase; AltName: Full=Vitamin-B12 dependent methionine synthase; Short=MS;+++[B1ANE3_HUMAN|Unreviewed]SubName: Full=Methionine synthase {ECO:0000313|Ensembl:ENSP00000355535}; Flags: Fragment;+++[B7ZLW8_HUMAN|Unreviewed]RecName: Full=Methionine synthase {ECO:0000256|PIRNR:PIRNR000381}; EC=2.1.1.13 {ECO:0000256|PIRNR:PIRNR000381}; AltName: Full=5-methyltetrahydrofolate--homocysteine methyltransferase {ECO:0000256|PIRNR:PIRNR000381};"]
[4604,"'MYBPC1'",121,141,56,106,null,"H00811///Distal arthrogryposis (DA)+++H00865///Lethal congenital contractural syndrome (LCCS)",null,null,"GO:0031430///M band+++GO:0030017///sarcomere+++GO:0032982///myosin filament+++GO:0030018///Z disc+++GO:0005829///cytosol+++GO:0030016///myofibril+++GO:0005865///striated muscle thin filament","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0051015///actin filament binding+++GO:0051371///muscle alpha-actinin binding+++GO:0031432///titin binding","GO:0045214///sarcomere organization+++GO:0006936///muscle contraction+++GO:0048739///cardiac muscle fiber development+++GO:0055003///cardiac myofibril assembly+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0007155///cell adhesion+++GO:0030240///skeletal muscle thin filament assembly+++GO:0030049///muscle filament sliding+++GO:0030241///skeletal muscle myosin thick filament assembly","myosin binding protein C, slow type","[MYPC1_HUMAN|Reviewed]RecName: Full=Myosin-binding protein C, slow-type; Short=Slow MyBP-C; AltName: Full=C-protein, skeletal muscle slow isoform;+++[A8KAB1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78685, highly similar to Homo sapiens myosin binding protein C, slow type (MYBPC1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF85665.1};+++[B3KPP3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32025 fis, clone NTONG1000213, highly similar to MYOSIN-BINDING PROTEIN C, SLOW-TYPE {ECO:0000313|EMBL:BAG51755.1};+++[F8VZE0_HUMAN|Unreviewed]SubName: Full=Myosin-binding protein C, slow-type {ECO:0000313|Ensembl:ENSP00000447362};+++[F8VZY0_HUMAN|Unreviewed]SubName: Full=Myosin-binding protein C, slow-type {ECO:0000313|Ensembl:ENSP00000447660};+++[F8W1Z9_HUMAN|Unreviewed]SubName: Full=Myosin-binding protein C, slow-type {ECO:0000313|Ensembl:ENSP00000447404}; Flags: Fragment;+++[G3V1V7_HUMAN|Unreviewed]SubName: Full=Myosin binding protein C, slow type, isoform CRA_e {ECO:0000313|EMBL:EAW97667.1}; SubName: Full=Myosin-binding protein C, slow-type {ECO:0000313|Ensembl:ENSP00000447116};+++[Q6P096_HUMAN|Unreviewed]SubName: Full=MYBPC1 protein {ECO:0000313|EMBL:AAH65720.1}; Flags: Fragment;+++[Q86TA8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451M091 {ECO:0000313|EMBL:CAD89927.1};"]
[4620,"'MYH2'",11,9,4,8,"04530///Tight junction","H02052///Sebastian syndrome+++H02051///May-Hegglin anomaly+++H01229///Inclusion body myopathy 3 (IBM3)+++H00872///Trismus-pseudocamptodactyly syndrome+++H00578///Epstein syndrome+++H00801///Familial thoracic aortic aneurysm and dissection (TAAD)+++H00233///MYH9-related disease+++H00811///Distal arthrogryposis (DA)+++H00604///Deafness, autosomal dominant+++H01740///Macrothrombocytopenia+++H01630///Patent ductus arteriosus+++H02053///Fechtner syndrome",null,null,"GO:0030017///sarcomere+++GO:0005737///cytoplasm+++GO:0032982///myosin filament+++GO:0016459///myosin complex+++GO:0005859///muscle myosin complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030016///myofibril+++GO:0032991///protein-containing complex","GO:0042803///protein homodimerization activity+++GO:0005516///calmodulin binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0051015///actin filament binding+++GO:0005524///ATP binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0003774///motor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0006936///muscle contraction+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030049///muscle filament sliding","myosin heavy chain 2","[MYH2_HUMAN|Reviewed]RecName: Full=Myosin-2; AltName: Full=Myosin heavy chain 2; AltName: Full=Myosin heavy chain 2a; Short=MyHC-2a; AltName: Full=Myosin heavy chain IIa; Short=MyHC-IIa; AltName: Full=Myosin heavy chain, skeletal muscle, adult 2;+++[E7EX84_HUMAN|Unreviewed]SubName: Full=Myosin-2 {ECO:0000313|Ensembl:ENSP00000399348}; Flags: Fragment;+++[J3QLR0_HUMAN|Unreviewed]SubName: Full=Myosin-2 {ECO:0000313|Ensembl:ENSP00000463668}; Flags: Fragment;"]
[4645,"'MYO5B'",625,574,562,587,null,"H02022///Griscelli syndrome+++H00101///Other phagocyte defects+++H01174///Congenital diarrhea",null,null,"GO:0045179///apical cortex+++GO:0016459///myosin complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0055037///recycling endosome","GO:0005515///protein binding+++GO:0000146///microfilament motor activity+++GO:0003774///motor activity+++GO:0005524///ATP binding+++GO:0003779///actin binding+++GO:0005516///calmodulin binding+++GO:0000166///nucleotide binding+++GO:0051015///actin filament binding+++GO:0017137///Rab GTPase binding","GO:0016192///vesicle-mediated transport+++GO:0016197///endosomal transport+++GO:0003091///renal water homeostasis+++GO:0015031///protein transport","myosin VB","[MYO5B_HUMAN|Reviewed]RecName: Full=Unconventional myosin-Vb;+++[A0A0A0MR36_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Vb {ECO:0000313|Ensembl:ENSP00000315531}; Flags: Fragment;+++[Q7Z7A5_HUMAN|Unreviewed]SubName: Full=Myosin 5B {ECO:0000313|EMBL:AAP42074.1};"]
[4665,"'NAB2'",315,274,228,272.333333333333,"05200///Pathways in cancer+++04217///Necroptosis+++04658///Th1 and Th2 cell differentiation+++05321///Inflammatory bowel disease (IBD)+++05161///Hepatitis B+++04659///Th17 cell differentiation+++04630///Jak-STAT signaling pathway",null,"M00684///JAK-STAT signaling",null,"GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0003714///transcription corepressor activity","GO:0042552///myelination+++GO:0014037///Schwann cell differentiation+++GO:0045682///regulation of epidermis development+++GO:1902949///positive regulation of tau-protein kinase activity+++GO:0008283///cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0016480///negative regulation of transcription by RNA polymerase III+++GO:0001958///endochondral ossification+++GO:0006355///regulation of transcription, DNA-templated","NGFI-A binding protein 2","[NAB2_HUMAN|Reviewed]RecName: Full=NGFI-A-binding protein 2; AltName: Full=EGR-1-binding protein 2; AltName: Full=Melanoma-associated delayed early response protein; Short=Protein MADER;"]
[4681,"'NBL1'",761,560,689.1,670.033333333333,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0016015///morphogen activity+++GO:0005515///protein binding+++GO:0036122///BMP binding+++GO:0042803///protein homodimerization activity","GO:0010469///regulation of signaling receptor activity+++GO:0045666///positive regulation of neuron differentiation+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:0048263///determination of dorsal identity+++GO:0048812///neuron projection morphogenesis+++GO:0038098///sequestering of BMP from receptor via BMP binding+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0007399///nervous system development","NBL1, DAN family BMP antagonist","[NBL1_HUMAN|Reviewed]RecName: Full=Neuroblastoma suppressor of tumorigenicity 1; AltName: Full=DAN domain family member 1; AltName: Full=Protein N03; AltName: Full=Zinc finger protein DAN; Flags: Precursor;+++[A0A087WTY6_HUMAN|Unreviewed]SubName: Full=Neuroblastoma suppressor of tumorigenicity 1 {ECO:0000313|Ensembl:ENSP00000478223};+++[A3KFI1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma suppressor of tumorigenicity 1 {ECO:0000313|Ensembl:ENSP00000391858}; Flags: Fragment;+++[A3KFI2_HUMAN|Unreviewed]SubName: Full=Neuroblastoma suppressor of tumorigenicity 1 {ECO:0000313|Ensembl:ENSP00000399333}; Flags: Fragment;+++[A3KFI3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma suppressor of tumorigenicity 1 {ECO:0000313|Ensembl:ENSP00000400250}; Flags: Fragment;+++[A3KFI4_HUMAN|Unreviewed]SubName: Full=Neuroblastoma suppressor of tumorigenicity 1 {ECO:0000313|Ensembl:ENSP00000412419}; Flags: Fragment;+++[A3KFI5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma suppressor of tumorigenicity 1 {ECO:0000313|Ensembl:ENSP00000390607}; Flags: Fragment;+++[E5RFZ1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma suppressor of tumorigenicity 1 {ECO:0000313|Ensembl:ENSP00000394079}; Flags: Fragment;"]
[4702,"'NDUFA8'",520,505,552,525.666666666667,"01100///Metabolic pathways+++05016///Huntington's disease+++04714///Thermogenesis+++05010///Alzheimer's disease+++04723///Retrograde endocannabinoid signaling+++00190///Oxidative phosphorylation+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)",null,"M00146///NADH dehydrogenase (ubiquinone) 1 alpha subcomplex",null,"GO:0005747///mitochondrial respiratory chain complex I+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane+++GO:0070469///respiratory chain","GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0044877///protein-containing complex binding","GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0055114///oxidation-reduction process","NADH:ubiquinone oxidoreductase subunit A8","[NDUA8_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; AltName: Full=Complex I-19kD; Short=CI-19kD; AltName: Full=Complex I-PGIV; Short=CI-PGIV; AltName: Full=NADH-ubiquinone oxidoreductase 19 kDa subunit;+++[B7Z768_HUMAN|Unreviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 {ECO:0000256|PIRNR:PIRNR017016};"]
[4716,"'NDUFB10'",1479,1512,1318,1436.33333333333,"00190///Oxidative phosphorylation+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04723///Retrograde endocannabinoid signaling+++05016///Huntington's disease+++04714///Thermogenesis+++05012///Parkinson's disease+++05010///Alzheimer's disease+++01100///Metabolic pathways",null,"M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0070469///respiratory chain","GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0055114///oxidation-reduction process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly","NADH:ubiquinone oxidoreductase subunit B10","[NDUBA_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10; AltName: Full=Complex I-PDSW; Short=CI-PDSW; AltName: Full=NADH-ubiquinone oxidoreductase PDSW subunit;+++[A8K761_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase (Ubiquinone) 1 beta subcomplex, 10, 22kDa, isoform CRA_b {ECO:0000313|EMBL:EAW85598.1}; SubName: Full=cDNA FLJ78612, highly similar to Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa (NDUFB10), mRNA {ECO:0000313|EMBL:BAF84565.1}; SubName: Full=cDNA, FLJ92003, Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10,22kDa (NDUFB10), mRNA {ECO:0000313|EMBL:BAG34687.1};+++[H3BPJ9_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 {ECO:0000313|Ensembl:ENSP00000455348};+++[H3BV16_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 {ECO:0000313|Ensembl:ENSP00000457908}; Flags: Fragment;+++[Q96RX5_HUMAN|Unreviewed]SubName: Full=NADH ubiquinone oxidoreductase PDSW subunit (RH 16p13.3) {ECO:0000313|EMBL:AAK61302.1}; Flags: Fragment;"]
[4718,"'NDUFC2'",798.82,618.91,653.5,690.41,"04932///Non-alcoholic fatty liver disease (NAFLD)+++04723///Retrograde endocannabinoid signaling+++01100///Metabolic pathways+++04714///Thermogenesis+++05012///Parkinson's disease+++05016///Huntington's disease+++05010///Alzheimer's disease+++00190///Oxidative phosphorylation",null,"M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0005739///mitochondrion+++GO:0070469///respiratory chain+++GO:0035577///azurophil granule membrane+++GO:0005737///cytoplasm+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005743///mitochondrial inner membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0043312///neutrophil degranulation+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0055114///oxidation-reduction process","NADH:ubiquinone oxidoreductase subunit C2","[NDUC2_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2; AltName: Full=Complex I-B14.5b; Short=CI-B14.5b; AltName: Full=Human lung cancer oncogene 1 protein; Short=HLC-1; AltName: Full=NADH-ubiquinone oxidoreductase subunit B14.5b;+++[A0A024R5K6_HUMAN|Unreviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2 {ECO:0000256|PIRNR:PIRNR017834};+++[E9PM14_HUMAN|Unreviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2 {ECO:0000256|PIRNR:PIRNR017834};+++[E9PRJ5_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2 {ECO:0000313|Ensembl:ENSP00000432253};"]
[4735,"'SEPT2'",5720.51,4743,5033.96,5165.82333333333,"05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0005930///axoneme+++GO:0097730///non-motile cilium+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0060170///ciliary membrane+++GO:0031105///septin complex+++GO:0000145///exocyst+++GO:0034364///high-density lipoprotein particle+++GO:0005634///nucleus+++GO:0032391///photoreceptor connecting cilium+++GO:0005829///cytosol+++GO:0032154///cleavage furrow+++GO:0005886///plasma membrane+++GO:0097227///sperm annulus+++GO:0000777///condensed chromosome kinetochore+++GO:0030496///midbody+++GO:0048471///perinuclear region of cytoplasm","GO:0045296///cadherin binding+++GO:0008289///lipid binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0005525///GTP binding","GO:0006869///lipid transport+++GO:0060271///cilium assembly+++GO:0008203///cholesterol metabolic process+++GO:0031175///neuron projection development+++GO:0007224///smoothened signaling pathway+++GO:0034384///high-density lipoprotein particle clearance+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0007283///spermatogenesis","septin 2","[SEPT2_HUMAN|Reviewed]RecName: Full=Septin-2; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 5; Short=NEDD-5;"]
[4756,"'NEO1'",3395,4106,3431,3644,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0098797///plasma membrane protein complex","GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0039706///co-receptor binding","GO:0007399///nervous system development+++GO:0007155///cell adhesion+++GO:0055072///iron ion homeostasis+++GO:0007411///axon guidance+++GO:0030513///positive regulation of BMP signaling pathway","neogenin 1","[NEO1_HUMAN|Reviewed]RecName: Full=Neogenin; AltName: Full=Immunoglobulin superfamily DCC subclass member 2; Flags: Precursor;+++[A0A024R610_HUMAN|Unreviewed]SubName: Full=Neogenin homolog 1 (Chicken), isoform CRA_a {ECO:0000313|EMBL:EAW77924.1};+++[Q59FP8_HUMAN|Unreviewed]SubName: Full=Neogenin homolog 1 variant {ECO:0000313|EMBL:BAD92649.1}; Flags: Fragment;"]
[4782,"'NFIC'",3035,3452,3250,3245.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0001650///fibrillar center","GO:0003700///DNA-binding transcription factor activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0042475///odontogenesis of dentin-containing tooth+++GO:0006366///transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II","nuclear factor I C","[NFIC_HUMAN|Reviewed]RecName: Full=Nuclear factor 1 C-type; Short=NF1-C; Short=Nuclear factor 1/C; AltName: Full=CCAAT-box-binding transcription factor; Short=CTF; AltName: Full=Nuclear factor I/C; Short=NF-I/C; Short=NFI-C; AltName: Full=TGGCA-binding protein;+++[A0A286YEX4_HUMAN|Unreviewed]RecName: Full=Nuclear factor 1 {ECO:0000256|RuleBase:RU000690};+++[B7Z4T6_HUMAN|Unreviewed]RecName: Full=Nuclear factor 1 {ECO:0000256|RuleBase:RU000690};+++[Q13051_HUMAN|Unreviewed]SubName: Full=Nuclear factor I {ECO:0000313|EMBL:AAB52370.1}; Flags: Fragment;+++[Q6FI30_HUMAN|Unreviewed]RecName: Full=Nuclear factor 1 {ECO:0000256|RuleBase:RU000690};"]
[4803,"'NGF'",73,67,71,70.3333333333333,"04015///Rap1 signaling pathway+++04010///MAPK signaling pathway+++04014///Ras signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04151///PI3K-Akt signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04722///Neurotrophin signaling pathway+++04210///Apoptosis","H00265///Hereditary sensory and autonomic neuropathy (HSAN)",null,null,"GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0008021///synaptic vesicle+++GO:0030425///dendrite+++GO:0031410///cytoplasmic vesicle+++GO:0030424///axon+++GO:0005576///extracellular region","GO:0030414///peptidase inhibitor activity+++GO:0005163///nerve growth factor receptor binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0004857///enzyme inhibitor activity+++GO:0038177///death receptor agonist activity+++GO:0008083///growth factor activity+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0048015///phosphatidylinositol-mediated signaling+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0045664///regulation of neuron differentiation+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0038180///nerve growth factor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0010469///regulation of signaling receptor activity+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0050772///positive regulation of axonogenesis+++GO:0045666///positive regulation of neuron differentiation+++GO:0048672///positive regulation of collateral sprouting+++GO:0010628///positive regulation of gene expression+++GO:0007613///memory+++GO:0051402///neuron apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010466///negative regulation of peptidase activity+++GO:0000186///activation of MAPKK activity+++GO:0043066///negative regulation of apoptotic process+++GO:0021675///nerve development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048812///neuron projection morphogenesis+++GO:0043388///positive regulation of DNA binding+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0032455///nerve growth factor processing+++GO:0007422///peripheral nervous system development+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0048011///neurotrophin TRK receptor signaling pathway","nerve growth factor","[NGF_HUMAN|Reviewed]RecName: Full=Beta-nerve growth factor; Short=Beta-NGF; Flags: Precursor;"]
[4829,"'NMBR'",0,0,1,0.333333333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0008528///G protein-coupled peptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004946///bombesin receptor activity","GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0031989///bombesin receptor signaling pathway","neuromedin B receptor","[NMBR_HUMAN|Reviewed]RecName: Full=Neuromedin-B receptor; Short=NMB-R; AltName: Full=Epididymis tissue protein Li 185a; AltName: Full=Neuromedin-B-preferring bombesin receptor;+++[Q4VBL0_HUMAN|Unreviewed]SubName: Full=Neuromedin B receptor {ECO:0000313|EMBL:AAH95542.1};"]
[4849,"'CNOT3'",1622,1789,1743,1718,"03018///RNA degradation",{"$nulls":3},"GO:0005829///cytosol+++GO:0030014///CCR4-NOT complex+++GO:0000932///P-body+++GO:0005634///nucleus+++GO:0030015///CCR4-NOT core complex+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0031047///gene silencing by RNA+++GO:2000036///regulation of stem cell population maintenance+++GO:0006417///regulation of translation+++GO:0001829///trophectodermal cell differentiation+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0017148///negative regulation of translation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","CCR4-NOT transcription complex subunit 3","[CNOT3_HUMAN|Reviewed]RecName: Full=CCR4-NOT transcription complex subunit 3; AltName: Full=CCR4-associated factor 3; AltName: Full=Leukocyte receptor cluster member 2;+++[A0A024R4R3_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex, subunit 3, isoform CRA_a {ECO:0000313|EMBL:EAW72194.1};+++[A0A087X0F9_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000483360}; Flags: Fragment;+++[A0A0G2JN65_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000480755}; Flags: Fragment;+++[A0A0G2JNJ7_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000481527}; Flags: Fragment;+++[A0A0G2JPP0_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000484020}; Flags: Fragment;+++[A0A2H2FJL5_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000484369};+++[A0A2R8Y4W0_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000494008}; Flags: Fragment;+++[A0A2R8Y691_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000495366}; Flags: Fragment;+++[A0A2R8Y6N5_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000495445}; Flags: Fragment;+++[A0A2R8Y7Z8_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000496534}; Flags: Fragment;+++[B7Z6J7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61662, highly similar to CCR4-NOT transcription complex subunit 3 {ECO:0000313|EMBL:BAH13283.1};+++[H0Y5X7_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000401703}; Flags: Fragment;+++[H7C148_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000398463}; Flags: Fragment;+++[H7C3F5_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000411587};+++[H7C5J4_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 3 {ECO:0000313|Ensembl:ENSP00000420064}; Flags: Fragment;"]
[4878,"'NPPA'",0,0,1,0.333333333333333,"04066///HIF-1 signaling pathway","H00731///Atrial fibrillation",null,null,"GO:0062023///collagen-containing extracellular matrix+++GO:0005737///cytoplasm+++GO:0042629///mast cell granule+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm","GO:0051427///hormone receptor binding+++GO:0005102///signaling receptor binding+++GO:0005184///neuropeptide hormone activity+++GO:0071855///neuropeptide receptor binding+++GO:0005515///protein binding+++GO:0005179///hormone activity","GO:0010469///regulation of signaling receptor activity+++GO:0006182///cGMP biosynthetic process+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0032868///response to insulin+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0006457///protein folding+++GO:1903779///regulation of cardiac conduction+++GO:1903595///positive regulation of histamine secretion by mast cell+++GO:0071260///cellular response to mechanical stimulus+++GO:0030308///negative regulation of cell growth+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0001666///response to hypoxia+++GO:0019934///cGMP-mediated signaling+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0050880///regulation of blood vessel size+++GO:1903766///positive regulation of potassium ion export across plasma membrane+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:1902261///positive regulation of delayed rectifier potassium channel activity+++GO:0035994///response to muscle stretch+++GO:0007565///female pregnancy+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0010460///positive regulation of heart rate+++GO:0007218///neuropeptide signaling pathway+++GO:1903815///negative regulation of collecting lymphatic vessel constriction+++GO:0008217///regulation of blood pressure+++GO:0044267///cellular protein metabolic process+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:0006367///transcription initiation from RNA polymerase II promoter","natriuretic peptide A","[ANF_HUMAN|Reviewed]RecName: Full=Natriuretic peptides A; AltName: Full=CDD-ANF; AltName: Full=Cardiodilatin; Short=CDD; AltName: Full=Cardiodilatin-related peptide; Short=CDP; AltName: Full=Prepronatriodilatin; Contains: RecName: Full=Atrial natriuretic factor; Short=ANF; AltName: Full=Atrial natriuretic peptide; Short=ANP; Flags: Precursor;+++[A0A087X094_HUMAN|Unreviewed]SubName: Full=Natriuretic peptides A {ECO:0000313|Ensembl:ENSP00000483195};+++[B0ZBE8_HUMAN|Unreviewed]SubName: Full=Natriuretic peptide A variant 1 {ECO:0000313|EMBL:ACA05915.1}; SubName: Full=Natriuretic peptides A {ECO:0000313|Ensembl:ENSP00000365659};"]
[4893,"'NRAS'",805,628,692,708.333333333333,"05167///Kaposi's sarcoma-associated herpesvirus infection+++04072///Phospholipase D signaling pathway+++04218///Cellular senescence+++04926///Relaxin signaling pathway+++05218///Melanoma+++04071///Sphingolipid signaling pathway+++05230///Central carbon metabolism in cancer+++04014///Ras signaling pathway+++04726///Serotonergic synapse+++01522///Endocrine resistance+++04722///Neurotrophin signaling pathway+++05165///Human papillomavirus infection+++04910///Insulin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04550///Signaling pathways regulating pluripotency of stem cells+++04664///Fc epsilon RI signaling pathway+++04919///Thyroid hormone signaling pathway+++05221///Acute myeloid leukemia+++05161///Hepatitis B+++04137///Mitophagy - animal+++04912///GnRH signaling pathway+++04370///VEGF signaling pathway+++04917///Prolactin signaling pathway+++04720///Long-term potentiation+++04210///Apoptosis+++04921///Oxytocin signaling pathway+++04012///ErbB signaling pathway+++04730///Long-term depression+++04714///Thermogenesis+++04213///Longevity regulating pathway - multiple species+++04015///Rap1 signaling pathway+++05226///Gastric cancer+++04915///Estrogen signaling pathway+++01521///EGFR tyrosine kinase inhibitor resistance+++05224///Breast cancer+++04371///Apelin signaling pathway+++04660///T cell receptor signaling pathway+++05211///Renal cell carcinoma+++04062///Chemokine signaling pathway+++04662///B cell receptor signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05205///Proteoglycans in cancer+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++04725///Cholinergic synapse+++05223///Non-small cell lung cancer+++05210///Colorectal cancer+++04810///Regulation of actin cytoskeleton+++04360///Axon guidance+++05166///HTLV-I infection+++04068///FoxO signaling pathway+++05206///MicroRNAs in cancer+++04916///Melanogenesis+++05216///Thyroid cancer+++05220///Chronic myeloid leukemia+++05213///Endometrial cancer+++05219///Bladder cancer+++05231///Choline metabolism in cancer+++04540///Gap junction+++04150///mTOR signaling pathway+++05225///Hepatocellular carcinoma+++05160///Hepatitis C+++05215///Prostate cancer+++05214///Glioma+++04010///MAPK signaling pathway+++05034///Alcoholism+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++04211///Longevity regulating pathway+++04140///Autophagy - animal","H00108///Autoimmune lymphoproliferative syndromes (ALPS)+++H00038///Melanoma+++H01481///Myelodysplastic syndrome (MDS)+++H00523///Noonan syndrome and related disorders+++H00032///Thyroid cancer+++H00018///Gastric cancer+++H00003///Acute myeloid leukemia (AML)+++H00010///Multiple myeloma+++H00033///Adrenal carcinoma+++H01738///Noonan syndrome+++H00016///Oral cancer+++H01666///Angiosarcoma",null,null,"GO:0005886///plasma membrane+++GO:0070821///tertiary granule membrane+++GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0044877///protein-containing complex binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:0007265///Ras protein signal transduction+++GO:0000165///MAPK cascade+++GO:0043312///neutrophil degranulation+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007165///signal transduction","NRAS proto-oncogene, GTPase","[RASN_HUMAN|Reviewed]RecName: Full=GTPase NRas; AltName: Full=Transforming protein N-Ras; Flags: Precursor;+++[Q5U091_HUMAN|Unreviewed]SubName: Full=Neuroblastoma RAS viral (V-ras) oncogene homolog {ECO:0000313|EMBL:AAV38540.1}; SubName: Full=Neuroblastoma RAS viral (V-ras) oncogene homolog, isoform CRA_a {ECO:0000313|EMBL:EAW56608.1};+++[Q9UM97_HUMAN|Unreviewed]SubName: Full=N-ras protein {ECO:0000313|EMBL:AAB29639.1}; Flags: Fragment;"]
[4919,"'ROR1'",537,591,581,569.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043235///receptor complex+++GO:0009986///cell surface+++GO:0043679///axon terminus+++GO:0001725///stress fiber+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane","GO:0005524///ATP binding+++GO:0017147///Wnt-protein binding+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:1904929///coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway+++GO:0042813///Wnt-activated receptor activity","GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007605///sensory perception of sound+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0048839///inner ear development+++GO:0014002///astrocyte development+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling","receptor tyrosine kinase like orphan receptor 1","[ROR1_HUMAN|Reviewed]RecName: Full=Inactive tyrosine-protein kinase transmembrane receptor ROR1 {ECO:0000305}; AltName: Full=Neurotrophic tyrosine kinase, receptor-related 1; Flags: Precursor;"]
[4929,"'NR4A2'",3,3,5,3.66666666666667,"04928///Parathyroid hormone synthesis, secretion and action+++04925///Aldosterone synthesis and secretion","H00057///Parkinson's disease (PD)",null,null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0003707///steroid hormone receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0008013///beta-catenin binding+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0035259///glucocorticoid receptor binding","GO:0021952///central nervous system projection neuron axonogenesis+++GO:0008344///adult locomotory behavior+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0001666///response to hypoxia+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0010467///gene expression+++GO:0043085///positive regulation of catalytic activity+++GO:0006351///transcription, DNA-templated+++GO:0042416///dopamine biosynthetic process+++GO:0071542///dopaminergic neuron differentiation+++GO:0042551///neuron maturation+++GO:0001975///response to amphetamine+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045444///fat cell differentiation+++GO:0009791///post-embryonic development+++GO:0034599///cellular response to oxidative stress+++GO:0001764///neuron migration+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:0042417///dopamine metabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0060070///canonical Wnt signaling pathway+++GO:0021953///central nervous system neuron differentiation+++GO:0007165///signal transduction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:0042053///regulation of dopamine metabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0021986///habenula development+++GO:0010468///regulation of gene expression+++GO:0031668///cellular response to extracellular stimulus+++GO:0007399///nervous system development+++GO:0030182///neuron differentiation+++GO:0051866///general adaptation syndrome+++GO:0006355///regulation of transcription, DNA-templated","nuclear receptor subfamily 4 group A member 2","[NR4A2_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 4 group A member 2; AltName: Full=Immediate-early response protein NOT; AltName: Full=Orphan nuclear receptor NURR1; AltName: Full=Transcriptionally-inducible nuclear receptor;+++[A0A0S2Z418_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 isoform 2 {ECO:0000313|EMBL:ALQ33697.1}; Flags: Fragment;+++[C0KWD1_HUMAN|Unreviewed]SubName: Full=Orphan nuclear receptor NR4A2 isoform 1 {ECO:0000313|EMBL:ACN32470.1}; Flags: Fragment;+++[C0KWD2_HUMAN|Unreviewed]SubName: Full=Orphan nuclear receptor NR4A2 isoform 2 {ECO:0000313|EMBL:ACN32471.1}; Flags: Fragment;+++[C9IYM5_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000406808}; Flags: Fragment;+++[C9J8W4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000410952};+++[C9JWQ1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000388120}; Flags: Fragment;+++[E9PBQ4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000415632};+++[F1D8N6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor related 1 {ECO:0000313|EMBL:ADZ17335.1}; SubName: Full=Nuclear receptor subfamily 4 group A member 2 isoform 1 {ECO:0000313|EMBL:ALQ33696.1};+++[F1DAL2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor related 1 {ECO:0000313|EMBL:ADZ17383.1};+++[F8W6I3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000386993};+++[H7BZ00_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000385379}; Flags: Fragment;+++[Q53EL4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4, group A, member 2 isoform a variant {ECO:0000313|EMBL:BAD97345.1}; Flags: Fragment;"]
[4942,"'OAT'",730,609,660,666.333333333333,"01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00330///Arginine and proline metabolism+++01130///Biosynthesis of antibiotics","H01400///Secondary hyperammonemia+++H00189///Ornithinaemia",null,"R00667///L-Ornithine:2-oxo-acid aminotransferase   L-Ornithine + 2-Oxoglutarate <=> L-Glutamate 5-semialdehyde + L-Glutamate","GO:0005759///mitochondrial matrix+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0003824///catalytic activity+++GO:0030170///pyridoxal phosphate binding+++GO:0016740///transferase activity+++GO:0004587///ornithine-oxo-acid transaminase activity+++GO:0008483///transaminase activity","GO:0007601///visual perception+++GO:0055129///L-proline biosynthetic process+++GO:0019544///arginine catabolic process to glutamate+++GO:0008652///cellular amino acid biosynthetic process+++GO:0010121///arginine catabolic process to proline via ornithine+++GO:0034214///protein hexamerization","ornithine aminotransferase","[OAT_HUMAN|Reviewed]RecName: Full=Ornithine aminotransferase, mitochondrial; EC=2.6.1.13; AltName: Full=Ornithine delta-aminotransferase; AltName: Full=Ornithine--oxo-acid aminotransferase; Contains: RecName: Full=Ornithine aminotransferase, hepatic form; Contains: RecName: Full=Ornithine aminotransferase, renal form; Flags: Precursor;+++[A0A140VJQ4_HUMAN|Unreviewed]RecName: Full=Ornithine aminotransferase {ECO:0000256|RuleBase:RU365036}; EC=2.6.1.13 {ECO:0000256|RuleBase:RU365036};"]
[4978,"'OPCML'",1149.7,1680.35,1375.54,1401.86333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031225///anchored component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region","GO:0005515///protein binding","GO:0008038///neuron recognition+++GO:0007155///cell adhesion","opioid binding protein/cell adhesion molecule like","[OPCM_HUMAN|Reviewed]RecName: Full=Opioid-binding protein/cell adhesion molecule; Short=OBCAM; Short=OPCML; Short=Opioid-binding cell adhesion molecule; AltName: Full=IgLON family member 1; Flags: Precursor;+++[A8K0Y0_HUMAN|Unreviewed]SubName: Full=Opioid binding protein/cell adhesion molecule-like preprotein isoform a {ECO:0000313|EMBL:ACB56655.1}; SubName: Full=Opioid binding protein/cell adhesion molecule-like, isoform CRA_a {ECO:0000313|EMBL:EAW67804.1}; SubName: Full=cDNA FLJ76211, highly similar to Homo sapiens opioid binding protein/cell adhesion molecule-like(OPCML), mRNA {ECO:0000313|EMBL:BAF82384.1};+++[B2CZX3_HUMAN|Unreviewed]SubName: Full=Opioid binding protein/cell adhesion molecule-like isoform d {ECO:0000313|EMBL:ACB56658.1}; SubName: Full=cDNA, FLJ79172, highly similar to Opioid-binding protein/cell adhesion moleculeprecursor {ECO:0000313|EMBL:BAH14644.1};+++[B7ZLQ0_HUMAN|Unreviewed]SubName: Full=OPCML protein {ECO:0000313|EMBL:AAI43946.1};+++[Q6B0I4_HUMAN|Unreviewed]SubName: Full=Opioid binding protein/cell adhesion molecule-like {ECO:0000313|EMBL:AAH74742.1};"]
[4988,"'OPRM1'",2.71,4.82,1,2.84333333333333,"05032///Morphine addiction+++04080///Neuroactive ligand-receptor interaction+++04915///Estrogen signaling pathway","H01611///Alcohol dependence",null,null,"GO:0005737///cytoplasm+++GO:0032839///dendrite cytoplasm+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0045121///membrane raft+++GO:0097444///spine apparatus+++GO:0042383///sarcolemma+++GO:0043204///perikaryon+++GO:0030425///dendrite+++GO:0005887///integral component of plasma membrane+++GO:0030424///axon+++GO:0032590///dendrite membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0005925///focal adhesion+++GO:0016021///integral component of membrane+++GO:0005623///cell+++GO:0005794///Golgi apparatus+++GO:0099055///integral component of postsynaptic membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum","GO:0005245///voltage-gated calcium channel activity+++GO:0019904///protein domain specific binding+++GO:0004930///G protein-coupled receptor activity+++GO:0031681///G-protein beta-subunit binding+++GO:0004979///beta-endorphin receptor activity+++GO:0042923///neuropeptide binding+++GO:0005515///protein binding+++GO:0004985///opioid receptor activity+++GO:0031005///filamin binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0038047///morphine receptor activity+++GO:0008022///protein C-terminus binding","GO:0042755///eating behavior+++GO:0071315///cellular response to morphine+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0032094///response to food+++GO:0007600///sensory perception+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0002438///acute inflammatory response to antigenic stimulus+++GO:0070848///response to growth factor+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007165///signal transduction+++GO:0044849///estrous cycle+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0048149///behavioral response to ethanol+++GO:0080135///regulation of cellular response to stress+++GO:0042060///wound healing+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0032496///response to lipopolysaccharide+++GO:0061358///negative regulation of Wnt protein secretion+++GO:0051930///regulation of sensory perception of pain+++GO:0043278///response to morphine+++GO:0050769///positive regulation of neurogenesis+++GO:0007626///locomotory behavior+++GO:0031635///adenylate cyclase-inhibiting opioid receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0019233///sensory perception of pain+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0070588///calcium ion transmembrane transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:2000310///regulation of NMDA receptor activity+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0060079///excitatory postsynaptic potential+++GO:0032100///positive regulation of appetite+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0042220///response to cocaine+++GO:0045471///response to ethanol+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0009314///response to radiation+++GO:0038003///opioid receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","opioid receptor mu 1","[OPRM_HUMAN|Reviewed]RecName: Full=Mu-type opioid receptor; Short=M-OR-1; Short=MOR-1; AltName: Full=Mu opiate receptor; AltName: Full=Mu opioid receptor; Short=MOP; Short=hMOP;+++[A0A089PQW6_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AIQ84876.1}; Flags: Fragment;+++[A0A0F6RA07_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AKE49351.1}; Flags: Fragment;+++[A0A0F6RAI2_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AKE49349.1}; Flags: Fragment;+++[A0A0F6TMB4_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AKE49353.1}; Flags: Fragment;+++[A0A0F6TMM4_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AKE49348.1}; Flags: Fragment;+++[A0A0F6TMT4_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AKE49352.1}; Flags: Fragment;+++[A0A0F6TN24_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AKE49350.1}; Flags: Fragment;+++[B7SXT0_HUMAN|Unreviewed]SubName: Full=Opioid receptor mu {ECO:0000313|EMBL:ACJ65060.1}; Flags: Fragment;+++[B7SXT1_HUMAN|Unreviewed]SubName: Full=Mutant opioid receptor mu {ECO:0000313|EMBL:ACJ65061.1}; Flags: Fragment;+++[B7SXT2_HUMAN|Unreviewed]SubName: Full=Mutant opioid receptor mu {ECO:0000313|EMBL:ACJ65062.1}; Flags: Fragment;+++[B7SXT3_HUMAN|Unreviewed]SubName: Full=Mutant opioid receptor mu {ECO:0000313|EMBL:ACJ65063.1}; Flags: Fragment;+++[B7SXT4_HUMAN|Unreviewed]SubName: Full=Mutant opioid receptor mu {ECO:0000313|EMBL:ACJ65064.1}; Flags: Fragment;+++[B8K2Q5_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1}; Flags: Fragment;+++[C7E9I8_HUMAN|Unreviewed]SubName: Full=Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313|EMBL:ACT35692.1}; Flags: Fragment;+++[C9E9Z9_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1}; Flags: Fragment;+++[C9EA00_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1}; Flags: Fragment;+++[E7EW71_HUMAN|Unreviewed]SubName: Full=Mu-type opioid receptor {ECO:0000313|Ensembl:ENSP00000430247}; Flags: Fragment;+++[G8XRH4_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor splice variant hMOR-1S {ECO:0000313|EMBL:ACM90348.1};+++[G8XRH5_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor hMOR-1a {ECO:0000313|EMBL:ACM90349.1};+++[L0E130_HUMAN|Unreviewed]SubName: Full=Micro opioid receptor isoform hMOR-1A2 {ECO:0000313|EMBL:AGA35553.1}; SubName: Full=Mu-type opioid receptor {ECO:0000313|Ensembl:ENSP00000353598};+++[O43185_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AAC51877.1}; Flags: Fragment;+++[Q716A7_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor MOR-1O {ECO:0000313|EMBL:AAQ12260.1}; Flags: Fragment;+++[Q71V90_HUMAN|Unreviewed]SubName: Full=Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1}; Flags: Fragment;"]
[5026,"'P2RX5'",34,27,24,28.3333333333333,"04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005639///integral component of nuclear inner membrane+++GO:0098794///postsynapse+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0001614///purinergic nucleotide receptor activity+++GO:0005524///ATP binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity+++GO:0035381///ATP-gated ion channel activity","GO:0034220///ion transmembrane transport+++GO:0006812///cation transport+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0060079///excitatory postsynaptic potential+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0007399///nervous system development+++GO:0007596///blood coagulation+++GO:0098655///cation transmembrane transport+++GO:0033198///response to ATP","purinergic receptor P2X 5","[P2RX5_HUMAN|Reviewed]RecName: Full=P2X purinoceptor 5; Short=P2X5; AltName: Full=ATP receptor; AltName: Full=Purinergic receptor;+++[B4DEG2_HUMAN|Unreviewed]RecName: Full=P2X purinoceptor {ECO:0000256|RuleBase:RU000681};+++[H0YHT9_HUMAN|Unreviewed]SubName: Full=p2X purinoceptor 5 {ECO:0000313|Ensembl:ENSP00000447815}; Flags: Fragment;+++[H0YII8_HUMAN|Unreviewed]SubName: Full=p2X purinoceptor 5 {ECO:0000313|Ensembl:ENSP00000449495}; Flags: Fragment;+++[K7EQ78_HUMAN|Unreviewed]RecName: Full=p2X purinoceptor {ECO:0000256|RuleBase:RU000681};"]
[5036,"'PA2G4'",2889,3255,3305,3149.66666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0035578///azurophil granule lumen+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003723///RNA binding","GO:0045597///positive regulation of cell differentiation+++GO:0000055///ribosomal large subunit export from nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0006364///rRNA processing+++GO:0006417///regulation of translation+++GO:0008283///cell proliferation+++GO:0043312///neutrophil degranulation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007050///cell cycle arrest","proliferation-associated 2G4","[PA2G4_HUMAN|Reviewed]RecName: Full=Proliferation-associated protein 2G4; AltName: Full=Cell cycle protein p38-2G4 homolog; Short=hG4-1; AltName: Full=ErbB3-binding protein 1;+++[A0A024RB85_HUMAN|Unreviewed]SubName: Full=Proliferation-associated 2G4, 38kDa, isoform CRA_a {ECO:0000313|EMBL:EAW96885.1};+++[F8VR77_HUMAN|Unreviewed]SubName: Full=Proliferation-associated protein 2G4 {ECO:0000313|Ensembl:ENSP00000448557};+++[F8VZ69_HUMAN|Unreviewed]SubName: Full=Proliferation-associated protein 2G4 {ECO:0000313|Ensembl:ENSP00000447389}; Flags: Fragment;+++[F8W0A3_HUMAN|Unreviewed]SubName: Full=Proliferation-associated protein 2G4 {ECO:0000313|Ensembl:ENSP00000447615}; Flags: Fragment;+++[Q05D08_HUMAN|Unreviewed]SubName: Full=PA2G4 protein {ECO:0000313|EMBL:AAH19222.1}; Flags: Fragment;+++[Q6PIN5_HUMAN|Unreviewed]SubName: Full=PA2G4 protein {ECO:0000313|EMBL:AAH32111.1}; Flags: Fragment;"]
[50507,"'NOX4'",1024.45,691.03,685,800.16,"04933///AGE-RAGE signaling pathway in diabetic complications",{"$nulls":3},"GO:0043020///NADPH oxidase complex+++GO:0016021///integral component of membrane+++GO:0005730///nucleolus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0005634///nucleus+++GO:0001725///stress fiber+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0071944///cell periphery+++GO:0005739///mitochondrion","GO:0016491///oxidoreductase activity+++GO:0050664///oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor+++GO:0016174///NAD(P)H oxidase activity+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0000166///nucleotide binding+++GO:0009055///electron transfer activity+++GO:0020037///heme binding+++GO:0005515///protein binding+++GO:0072341///modified amino acid binding+++GO:0019826///oxygen sensor activity+++GO:1990782///protein tyrosine kinase binding+++GO:0050660///flavin adenine dinucleotide binding","GO:0072593///reactive oxygen species metabolic process+++GO:0071320///cellular response to cAMP+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0050667///homocysteine metabolic process+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0071480///cellular response to gamma radiation+++GO:0071333///cellular response to glucose stimulus+++GO:0006954///inflammatory response+++GO:0022900///electron transport chain+++GO:0003015///heart process+++GO:0055007///cardiac muscle cell differentiation+++GO:0007568///aging+++GO:0042554///superoxide anion generation+++GO:1903409///reactive oxygen species biosynthetic process+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0006801///superoxide metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0051496///positive regulation of stress fiber assembly+++GO:0010467///gene expression+++GO:0043065///positive regulation of apoptotic process+++GO:0034599///cellular response to oxidative stress+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0045453///bone resorption+++GO:0001666///response to hypoxia+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0043406///positive regulation of MAP kinase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0000902///cell morphogenesis+++GO:0055114///oxidation-reduction process+++GO:0007569///cell aging","NADPH oxidase 4","[NOX4_HUMAN|Reviewed]RecName: Full=NADPH oxidase 4; EC=1.6.3.-; AltName: Full=Kidney oxidase-1; Short=KOX-1; AltName: Full=Kidney superoxide-producing NADPH oxidase; AltName: Full=Renal NAD(P)H-oxidase;+++[B3KQ17_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32627 fis, clone SYNOV1000049, highly similar to NADPH oxidase 4 {ECO:0000313|EMBL:BAG51879.1};+++[B7Z523_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51025, highly similar to NADPH oxidase 4 {ECO:0000313|EMBL:BAH12759.1};+++[B7Z529_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51027, highly similar to NADPH oxidase 4 {ECO:0000313|EMBL:BAH12765.1};+++[E9PI95_HUMAN|Unreviewed]SubName: Full=NADPH oxidase 4 {ECO:0000313|Ensembl:ENSP00000436716};+++[E9PPP2_HUMAN|Unreviewed]SubName: Full=NADPH oxidase 4 {ECO:0000313|Ensembl:ENSP00000436970};+++[E9PR43_HUMAN|Unreviewed]SubName: Full=NADPH oxidase 4 {ECO:0000313|Ensembl:ENSP00000436093};"]
[5058,"'PAK1'",804,821,789,804.666666666667,"04011///MAPK signaling pathway - yeast+++04650///Natural killer cell mediated cytotoxicity+++04360///Axon guidance+++04810///Regulation of actin cytoskeleton+++04666///Fc gamma R-mediated phagocytosis+++04625///C-type lectin receptor signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04392///Hippo signaling pathway - multiple species+++04062///Chemokine signaling pathway+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++04510///Focal adhesion+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0032587///ruffle membrane+++GO:0001726///ruffle+++GO:0014704///intercalated disc+++GO:0071437///invadopodium+++GO:0005911///cell-cell junction+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0005737///cytoplasm+++GO:0030018///Z disc+++GO:0032991///protein-containing complex+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0048365///Rac GTPase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0005518///collagen binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0042802///identical protein binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043507///positive regulation of JUN kinase activity+++GO:0032147///activation of protein kinase activity+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:2001275///positive regulation of glucose import in response to insulin stimulus+++GO:0046777///protein autophosphorylation+++GO:0032869///cellular response to insulin stimulus+++GO:0042060///wound healing+++GO:0051496///positive regulation of stress fiber assembly+++GO:0045773///positive regulation of axon extension+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0001666///response to hypoxia+++GO:0008284///positive regulation of cell proliferation+++GO:0007266///Rho protein signal transduction+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006887///exocytosis+++GO:0048013///ephrin receptor signaling pathway+++GO:0031295///T cell costimulation+++GO:0030335///positive regulation of cell migration+++GO:0050852///T cell receptor signaling pathway+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0050770///regulation of axonogenesis+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0060244///negative regulation of cell proliferation involved in contact inhibition+++GO:0006915///apoptotic process+++GO:0048812///neuron projection morphogenesis+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0031116///positive regulation of microtubule polymerization+++GO:0042981///regulation of apoptotic process+++GO:0030010///establishment of cell polarity+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0007346///regulation of mitotic cell cycle+++GO:0031532///actin cytoskeleton reorganization+++GO:0006468///protein phosphorylation+++GO:0010763///positive regulation of fibroblast migration+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0021549///cerebellum development","p21 (RAC1) activated kinase 1","[PAK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 1 {ECO:0000303|PubMed:8805275}; EC=2.7.11.1 {ECO:0000269|PubMed:10551809, ECO:0000269|PubMed:22153498, ECO:0000269|PubMed:9032240}; AltName: Full=Alpha-PAK {ECO:0000303|PubMed:9528787}; AltName: Full=p21-activated kinase 1 {ECO:0000303|PubMed:9395435}; Short=PAK-1; AltName: Full=p65-PAK {ECO:0000250|UniProtKB:P35465};+++[A0A024R5P0_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};"]
[50717,"'DCAF8'",1567,1410,1342,1439.66666666667,null,"H01259///Giant axonal neuropathy",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination","DDB1 and CUL4 associated factor 8","[DCAF8_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 8; AltName: Full=WD repeat-containing protein 42A;+++[B7Z8C9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55437, highly similar to Homo sapiens WD repeat domain 42A (WDR42A), mRNA {ECO:0000313|EMBL:BAH13915.1};+++[Q5TAQ5_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000411875}; Flags: Fragment;+++[Q5TAQ6_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000409434}; Flags: Fragment;+++[Q5TAQ7_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000384118}; Flags: Fragment;+++[Q5TAQ8_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000413688}; Flags: Fragment;+++[V9GY54_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000476407};+++[V9GY98_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000476539}; Flags: Fragment;+++[V9GYQ9_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000477012}; Flags: Fragment;+++[V9GYZ9_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000477255}; Flags: Fragment;+++[V9GZ39_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 8 {ECO:0000313|Ensembl:ENSP00000477386}; Flags: Fragment;"]
[50813,"'COPS7A'",1202,1152,1164,1172.66666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0008180///COP9 signalosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0016032///viral process+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0000338///protein deneddylation+++GO:0043687///post-translational protein modification","COP9 signalosome subunit 7A","[CSN7A_HUMAN|Reviewed]RecName: Full=COP9 signalosome complex subunit 7a; Short=SGN7a; Short=Signalosome subunit 7a; AltName: Full=Dermal papilla-derived protein 10; AltName: Full=JAB1-containing signalosome subunit 7a;+++[F5GXT7_HUMAN|Unreviewed]SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000440972};+++[F5GYF7_HUMAN|Unreviewed]SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000440683}; Flags: Fragment;+++[F5H248_HUMAN|Unreviewed]SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000439547};+++[F5H3M6_HUMAN|Unreviewed]SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000445300};+++[F5H4U8_HUMAN|Unreviewed]SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000439949}; Flags: Fragment;+++[F5H4Z0_HUMAN|Unreviewed]SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000444807};+++[F5H7C6_HUMAN|Unreviewed]SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000442613}; Flags: Fragment;+++[G3XAP1_HUMAN|Unreviewed]SubName: Full=COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis), isoform CRA_b {ECO:0000313|EMBL:EAW88746.1}; SubName: Full=COP9 signalosome complex subunit 7a {ECO:0000313|Ensembl:ENSP00000438571};+++[Q567U8_HUMAN|Unreviewed]SubName: Full=COPS7A protein {ECO:0000313|EMBL:AAH93015.1};"]
[509,"'ATP5F1C'",1460,1358,1362,1393.33333333333,"01100///Metabolic pathways+++05016///Huntington's disease+++04714///Thermogenesis+++05010///Alzheimer's disease+++00190///Oxidative phosphorylation+++05012///Parkinson's disease",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0016020///membrane+++GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0043209///myelin sheath+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005753///mitochondrial proton-transporting ATP synthase complex","GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0022857///transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0003723///RNA binding","GO:0006754///ATP biosynthetic process+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0042407///cristae formation+++GO:0015986///ATP synthesis coupled proton transport+++GO:0006119///oxidative phosphorylation+++GO:0006811///ion transport","ATP synthase F1 subunit gamma","[ATPG_HUMAN|Reviewed]RecName: Full=ATP synthase subunit gamma, mitochondrial {ECO:0000305}; AltName: Full=ATP synthase F1 subunit gamma {ECO:0000312|HGNC:HGNC:833}; AltName: Full=F-ATPase gamma subunit; Flags: Precursor;+++[B4DL14_HUMAN|Unreviewed]RecName: Full=ATP synthase subunit gamma {ECO:0000256|RuleBase:RU004001};+++[Q8TAS0_HUMAN|Unreviewed]RecName: Full=ATP synthase subunit gamma {ECO:0000256|RuleBase:RU004001}; Flags: Fragment;"]
[5098,"'PCDHGC3'",3705.65,3971.27,3947.57,3874.83,{"$nulls":4},"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005509///calcium ion binding","GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0050808///synapse organization","protocadherin gamma subfamily C, 3","[PCDGK_HUMAN|Reviewed]RecName: Full=Protocadherin gamma-C3; Short=PCDH-gamma-C3; AltName: Full=Protocadherin-2; AltName: Full=Protocadherin-43; Short=PC-43; Flags: Precursor;+++[A0A087WYB5_HUMAN|Unreviewed]SubName: Full=Protocadherin gamma-C3 {ECO:0000313|Ensembl:ENSP00000481673};+++[A0A087X1P2_HUMAN|Unreviewed]SubName: Full=Protocadherin gamma-C3 {ECO:0000313|Ensembl:ENSP00000484352}; Flags: Fragment;+++[Q9BR81_HUMAN|Unreviewed]SubName: Full=Protocadherin gamma subfamily C, 3 {ECO:0000313|EMBL:AAH06439.1}; SubName: Full=Protocadherin gamma-C3 {ECO:0000313|Ensembl:ENSP00000483383};"]
[51008,"'ASCC1'",238.99,281.21,244.49,254.896666666667,null,"H01901///Barrett's esophagus",null,null,"GO:0016607///nuclear speck+++GO:0005667///transcription factor complex+++GO:0031594///neuromuscular junction+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006307///DNA dealkylation involved in DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair","activating signal cointegrator 1 complex subunit 1","[ASCC1_HUMAN|Reviewed]RecName: Full=Activating signal cointegrator 1 complex subunit 1; AltName: Full=ASC-1 complex subunit p50 {ECO:0000303|PubMed:12077347}; AltName: Full=Trip4 complex subunit p50 {ECO:0000303|PubMed:12077347};+++[A0A024QZM0_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW54445.1};+++[E9PJM2_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000431746}; Flags: Fragment;+++[E9PKM6_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000431573}; Flags: Fragment;+++[E9PL92_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000431419}; Flags: Fragment;+++[E9PM82_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000431255}; Flags: Fragment;+++[E9PQ44_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000434468};+++[E9PQZ6_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000432418}; Flags: Fragment;+++[E9PR40_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000436098}; Flags: Fragment;+++[H0YCB3_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000431299}; Flags: Fragment;+++[H0YE76_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000435147}; Flags: Fragment;+++[H0YE79_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000435191}; Flags: Fragment;+++[H0YER2_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000436409}; Flags: Fragment;"]
[51028,"'VPS36'",268,301,309,292.666666666667,"04144///Endocytosis",null,"M00410///ESCRT-II complex",null,"GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0000814///ESCRT II complex+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005634///nucleus+++GO:0005768///endosome+++GO:0031902///late endosome membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0008022///protein C-terminus binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0043130///ubiquitin binding","GO:0015031///protein transport+++GO:0036258///multivesicular body assembly+++GO:0016236///macroautophagy+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0016197///endosomal transport+++GO:0043328///protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway","vacuolar protein sorting 36 homolog","[VPS36_HUMAN|Reviewed]RecName: Full=Vacuolar protein-sorting-associated protein 36; AltName: Full=ELL-associated protein of 45 kDa; AltName: Full=ESCRT-II complex subunit VPS36;"]
[51059,"'FAM135B'",6,16,12,11.3333333333333,{"$nulls":4},"GO:0097014///ciliary plasm+++GO:0035253///ciliary rootlet+++GO:0005737///cytoplasm+++GO:0036064///ciliary basal body+++GO:0035869///ciliary transition zone+++GO:0005829///cytosol","GO:0030145///manganese ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005524///ATP binding","GO:0044255///cellular lipid metabolic process","family with sequence similarity 135 member B","[F135B_HUMAN|Reviewed]RecName: Full=Protein FAM135B;+++[E5RFQ7_HUMAN|Unreviewed]SubName: Full=Protein FAM135B {ECO:0000313|Ensembl:ENSP00000428017}; Flags: Fragment;+++[E5RH68_HUMAN|Unreviewed]SubName: Full=Protein FAM135B {ECO:0000313|Ensembl:ENSP00000429874};+++[H0YBQ7_HUMAN|Unreviewed]SubName: Full=Protein FAM135B {ECO:0000313|Ensembl:ENSP00000430088}; Flags: Fragment;+++[J3QSR3_HUMAN|Unreviewed]SubName: Full=Protein FAM135B {ECO:0000313|Ensembl:ENSP00000160713}; Flags: Fragment;"]
[51078,"'THAP4'",863,864,767,831.333333333333,"04140///Autophagy - animal+++04138///Autophagy - yeast+++04136///Autophagy - other",{"$nulls":3},"GO:0005575///cellular_component","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0020037///heme binding","GO:0008150///biological_process+++GO:0006357///regulation of transcription by RNA polymerase II","THAP domain containing 4","[THAP4_HUMAN|Reviewed]RecName: Full=THAP domain-containing protein 4;+++[B5MCC0_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000384352};+++[Q9BQ29_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000482312}; SubName: Full=THAP4 protein {ECO:0000313|EMBL:AAH01842.1};"]
[51095,"'TRNT1'",127,133,114,124.666666666667,"03013///RNA transport","H00768///Nonsyndromic autosomal recessive mental retardation (NS-ARMR)",null,"R09386///ATP:tRNA adenylyltransferase   tRNA with a 3' CC end + ATP <=> tRNA with a 3' CCA end + Diphosphate+++R09382///CTP,CTP,ATP:tRNA cytidylyl,cytidylyl,adenylyltransferase   tRNA precursor + 2 CTP + ATP <=> tRNA with a 3' CCA end + 3 Diphosphate+++R09383///CTP:tRNA cytidylyltransferase   tRNA precursor + CTP <=> tRNA with a 3' cytidine + Diphosphate+++R09384///CTP:tRNA cytidylyltransferase   tRNA with a 3' cytidine + CTP <=> tRNA with a 3' CC end + Diphosphate","GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0003723///RNA binding+++GO:0000049///tRNA binding+++GO:0016779///nucleotidyltransferase activity+++GO:0052928///CTP:3'-cytidine-tRNA cytidylyltransferase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0052929///ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0052927///CTP:tRNA cytidylyltransferase activity+++GO:0034062///5'-3' RNA polymerase activity","GO:0042780///tRNA 3'-end processing+++GO:1990180///mitochondrial tRNA 3'-end processing+++GO:0006396///RNA processing+++GO:0008033///tRNA processing+++GO:0001680///tRNA 3'-terminal CCA addition","tRNA nucleotidyl transferase 1","[TRNT1_HUMAN|Reviewed]RecName: Full=CCA tRNA nucleotidyltransferase 1, mitochondrial; EC=2.7.7.72 {ECO:0000269|PubMed:11504732}; AltName: Full=Mitochondrial tRNA nucleotidyl transferase, CCA-adding; AltName: Full=mt CCA-adding enzyme; AltName: Full=mt tRNA CCA-diphosphorylase; AltName: Full=mt tRNA CCA-pyrophosphorylase; AltName: Full=mt tRNA adenylyltransferase; Flags: Precursor;+++[A0A024R2H7_HUMAN|Unreviewed]SubName: Full=tRNA nucleotidyl transferase, CCA-adding, 1, isoform CRA_b {ECO:0000313|EMBL:EAW63889.1};+++[C9JRS7_HUMAN|Unreviewed]SubName: Full=CCA tRNA nucleotidyltransferase 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000388615}; Flags: Fragment;+++[F8W8C3_HUMAN|Unreviewed]SubName: Full=CCA tRNA nucleotidyltransferase 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000380881};"]
[51109,"'RDH11'",2332,2736,2444,2504,"00830///Retinol metabolism+++01100///Metabolic pathways",null,null,"R08380///11-cis-retinol: NADP+ oxidoreductase   11-cis-Retinol + NADP+ <=> 11-cis-Retinal + NADPH + H++++R08379///retinol: NADP+ oxidoreductase   Retinol + NADP+ <=> Retinal + NADPH + H++++R08383///9-cis-Retinol + NADP+ <=> 9-cis-Retinal + NADPH + H+","GO:0001917///photoreceptor inner segment+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005622///intracellular+++GO:0016020///membrane","GO:0016491///oxidoreductase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0052650///NADP-retinol dehydrogenase activity+++GO:0005515///protein binding+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0042574///retinal metabolic process+++GO:0055114///oxidation-reduction process+++GO:0042572///retinol metabolic process+++GO:0016062///adaptation of rhodopsin mediated signaling+++GO:0001523///retinoid metabolic process","retinol dehydrogenase 11","[RDH11_HUMAN|Reviewed]RecName: Full=Retinol dehydrogenase 11; EC=1.1.1.300; AltName: Full=Androgen-regulated short-chain dehydrogenase/reductase 1; AltName: Full=HCV core-binding protein HCBP12; AltName: Full=Prostate short-chain dehydrogenase/reductase 1; AltName: Full=Retinal reductase 1; Short=RalR1; AltName: Full=Short chain dehydrogenase/reductase family 7C member 1;+++[A0A0S2Z575_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 isoform 2 {ECO:0000313|EMBL:ALQ34086.1};+++[A0A0S2Z583_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 isoform 1 {ECO:0000313|EMBL:ALQ34085.1}; Flags: Fragment;+++[B3KQ19_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 (All-trans and 9-cis), isoform CRA_a {ECO:0000313|EMBL:EAW80948.1}; SubName: Full=cDNA FLJ32633 fis, clone SYNOV2000171, highly similar to Retinol dehydrogenase 11 {ECO:0000313|EMBL:BAG51881.1};+++[G3V234_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000450435}; Flags: Fragment;+++[G3V2G6_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000450651}; Flags: Fragment;+++[G3V3K0_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000451280};+++[G3V510_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000452108};+++[H0YJ46_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000450802}; Flags: Fragment;"]
[51127,"'TRIM17'",34,55,66,51.6666666666667,{"$nulls":4},"GO:0005575///cellular_component","GO:0030674///protein binding, bridging+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination+++GO:0032880///regulation of protein localization+++GO:0006914///autophagy","tripartite motif containing 17","[TRI17_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM17; EC=2.3.2.27; AltName: Full=RING finger protein 16; AltName: Full=RING-type E3 ubiquitin transferase TRIM17 {ECO:0000305}; AltName: Full=Testis RING finger protein; AltName: Full=Tripartite motif-containing protein 17;+++[A0A024R3T1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 17, isoform CRA_a {ECO:0000313|EMBL:EAW69873.1};+++[B3KP04_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 17, isoform CRA_b {ECO:0000313|EMBL:EAW69874.1}; SubName: Full=cDNA FLJ30864 fis, clone FEBRA2004091, highly similar to Tripartite motif-containing protein 17 {ECO:0000313|EMBL:BAG51516.1};+++[E5RI62_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM17 {ECO:0000313|Ensembl:ENSP00000429555}; Flags: Fragment;+++[E5RJW6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM17 {ECO:0000313|Ensembl:ENSP00000430468}; Flags: Fragment;+++[J3KNZ3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM17 {ECO:0000313|Ensembl:ENSP00000347794}; Flags: Fragment;+++[J3KQG0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM17 {ECO:0000313|Ensembl:ENSP00000397688}; Flags: Fragment;"]
[51148,"'CERCAM'",4217,3572,3497,3762,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane",null,"GO:0007159///leukocyte cell-cell adhesion+++GO:0007155///cell adhesion","cerebral endothelial cell adhesion molecule","[GT253_HUMAN|Reviewed]RecName: Full=Inactive glycosyltransferase 25 family member 3; AltName: Full=Cerebral endothelial cell adhesion molecule; Flags: Precursor;+++[A0A087WUJ5_HUMAN|Unreviewed]SubName: Full=Inactive glycosyltransferase 25 family member 3 {ECO:0000313|Ensembl:ENSP00000478713};+++[A0A087WYE2_HUMAN|Unreviewed]SubName: Full=Inactive glycosyltransferase 25 family member 3 {ECO:0000313|Ensembl:ENSP00000481729};+++[B7ZBS8_HUMAN|Unreviewed]SubName: Full=Inactive glycosyltransferase 25 family member 3 {ECO:0000313|Ensembl:ENSP00000402508}; Flags: Fragment;+++[B7ZBS9_HUMAN|Unreviewed]SubName: Full=Inactive glycosyltransferase 25 family member 3 {ECO:0000313|Ensembl:ENSP00000403766}; Flags: Fragment;+++[B7ZBT0_HUMAN|Unreviewed]SubName: Full=Inactive glycosyltransferase 25 family member 3 {ECO:0000313|Ensembl:ENSP00000402928}; Flags: Fragment;+++[X6RL83_HUMAN|Unreviewed]SubName: Full=Inactive glycosyltransferase 25 family member 3 {ECO:0000313|Ensembl:ENSP00000416676}; Flags: Fragment;"]
[51167,"'CYB5R4'",65,62,63,63.3333333333333,"00520///Amino sugar and nucleotide sugar metabolism","H00235///Methemoglobinemia",null,"R00100///NADH:ferricytochrome-b5 oxidoreductase   NADH + 2 Ferricytochrome b5 <=> NAD+ + 2 Ferrocytochrome b5 + H+","GO:0048471///perinuclear region of cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0016653///oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H","GO:0006091///generation of precursor metabolites and energy+++GO:0042593///glucose homeostasis+++GO:0015701///bicarbonate transport+++GO:0006801///superoxide metabolic process+++GO:0046677///response to antibiotic+++GO:0048468///cell development+++GO:0030073///insulin secretion+++GO:0003032///detection of oxygen+++GO:0055114///oxidation-reduction process","cytochrome b5 reductase 4","[NB5R4_HUMAN|Reviewed]RecName: Full=Cytochrome b5 reductase 4; EC=1.6.2.2; AltName: Full=Flavohemoprotein b5/b5R; Short=b5+b5R; AltName: Full=N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein; AltName: Full=cb5/cb5R;+++[A0A0A0MRM6_HUMAN|Unreviewed]SubName: Full=Cytochrome b5 reductase 4 {ECO:0000313|Ensembl:ENSP00000358693};"]
[51188,"'SS18L2'",63,78,81,74,{"$nulls":4},"GO:0005634///nucleus","GO:0003713///transcription coactivator activity","GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II","SS18 like 2","[S18L2_HUMAN|Reviewed]RecName: Full=SS18-like protein 2; AltName: Full=SYT homolog 2;+++[A0A024R2Q8_HUMAN|Unreviewed]SubName: Full=Synovial sarcoma translocation gene on chromosome 18-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW64658.1};"]
[5121,"'PCP4'",291,507,490,429.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005634///nucleus","GO:0005509///calcium ion binding+++GO:0005516///calmodulin binding+++GO:0005515///protein binding","GO:0099004///calmodulin dependent kinase signaling pathway+++GO:0045666///positive regulation of neuron differentiation","Purkinje cell protein 4","[PCP4_HUMAN|Reviewed]RecName: Full=Calmodulin regulator protein PCP4 {ECO:0000305}; AltName: Full=Brain-specific polypeptide PEP-19 {ECO:0000303|PubMed:8931698}; AltName: Full=Purkinje cell protein 4 {ECO:0000312|HGNC:HGNC:8742};+++[F6SSA2_HUMAN|Unreviewed]SubName: Full=Calmodulin regulator protein PCP4 {ECO:0000313|Ensembl:ENSP00000433172};"]
[51239,"'ANKRD39'",121,141,127,129.666666666667,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","ankyrin repeat domain 39","[ANR39_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 39;"]
[51246,"'SHISA5'",9211,9387,9159,9252.33333333333,"04115///p53 signaling pathway","H00290///Aicardi-Goutieres syndrome (AGS)+++H01000///Retinal vasculopathy with cerebral leukodystrophy (RVCL)+++H00291///Familial chilblain lupus (FCL)",null,null,"GO:0005788///endoplasmic reticulum lumen+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0031965///nuclear membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0050699///WW domain binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043687///post-translational protein modification+++GO:0044267///cellular protein metabolic process+++GO:0006915///apoptotic process+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator","shisa family member 5","[SHSA5_HUMAN|Reviewed]RecName: Full=Protein shisa-5; AltName: Full=Putative NF-kappa-B-activating protein 120; AltName: Full=Scotin; Flags: Precursor;+++[A0A024R2S8_HUMAN|Unreviewed]SubName: Full=Scotin, isoform CRA_a {ECO:0000313|EMBL:EAW64886.1};+++[A0A087WZK8_HUMAN|Unreviewed]SubName: Full=Protein shisa-5 {ECO:0000313|Ensembl:ENSP00000482723};+++[C9IZ46_HUMAN|Unreviewed]SubName: Full=Protein shisa-5 {ECO:0000313|Ensembl:ENSP00000412509}; Flags: Fragment;+++[F8WCE2_HUMAN|Unreviewed]SubName: Full=Protein shisa-5 {ECO:0000313|Ensembl:ENSP00000400498};+++[F8WDS1_HUMAN|Unreviewed]SubName: Full=Protein shisa-5 {ECO:0000313|Ensembl:ENSP00000415097};+++[F8WFD9_HUMAN|Unreviewed]SubName: Full=Protein shisa-5 {ECO:0000313|Ensembl:ENSP00000412811};+++[H7C2R0_HUMAN|Unreviewed]SubName: Full=Protein shisa-5 {ECO:0000313|Ensembl:ENSP00000407330}; Flags: Fragment;"]
[5128,"'CDK17'",330,345,351,342,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding","GO:0006468///protein phosphorylation+++GO:0051726///regulation of cell cycle+++GO:0016310///phosphorylation","cyclin dependent kinase 17","[CDK17_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 17; EC=2.7.11.22; AltName: Full=Cell division protein kinase 17; AltName: Full=PCTAIRE-motif protein kinase 2; AltName: Full=Serine/threonine-protein kinase PCTAIRE-2;+++[A0A024RBH0_HUMAN|Unreviewed]SubName: Full=PCTAIRE protein kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW97569.1};+++[F5H6Z0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 17 {ECO:0000313|Ensembl:ENSP00000442926};+++[F8VQZ9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 17 {ECO:0000313|Ensembl:ENSP00000450058}; Flags: Fragment;+++[F8VUX2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 17 {ECO:0000313|Ensembl:ENSP00000448132}; Flags: Fragment;+++[F8VZY6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 17 {ECO:0000313|Ensembl:ENSP00000447282}; Flags: Fragment;+++[F8W1S5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 17 {ECO:0000313|Ensembl:ENSP00000447441}; Flags: Fragment;"]
[51295,"'ECSIT'",444,560,444,482.666666666667,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0005515///protein binding","GO:0051341///regulation of oxidoreductase activity+++GO:0055114///oxidation-reduction process+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0045087///innate immune response+++GO:0002376///immune system process","ECSIT signalling integrator","[ECSIT_HUMAN|Reviewed]RecName: Full=Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; AltName: Full=Protein SITPEC; Flags: Precursor;+++[J3KTF5_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000462957}; Flags: Fragment;+++[K7EIK2_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000464783}; Flags: Fragment;+++[K7EJG5_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000465162}; Flags: Fragment;+++[K7EJI1_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000465181}; Flags: Fragment;+++[K7EM98_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000466415}; Flags: Fragment;+++[K7EN32_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000466762};+++[K7EPL5_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000467436}; Flags: Fragment;+++[K7ESM8_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000468783};"]
[51301,"'GCNT4'",6,5,5,5.33333333333333,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis",null,"M00056///O-glycan biosynthesis, mucin type core","R05912///UDP-N-acetyl-D-glucosamine + T antigen <=> UDP + G00025","GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0003829///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity+++GO:0008109///N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity","GO:0048872///homeostasis of number of cells+++GO:0005975///carbohydrate metabolic process+++GO:0060993///kidney morphogenesis+++GO:0048729///tissue morphogenesis+++GO:0006493///protein O-linked glycosylation+++GO:0002121///inter-male aggressive behavior+++GO:0006486///protein glycosylation+++GO:0016266///O-glycan processing+++GO:0042403///thyroid hormone metabolic process","glucosaminyl (N-acetyl) transferase 4, core 2","[GCNT4_HUMAN|Reviewed]RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4; EC=2.4.1.102 {ECO:0000269|PubMed:10753916}; AltName: Full=Core 2-branching enzyme 3; AltName: Full=Core2-GlcNAc-transferase 3; Short=C2GnT3;"]
[51315,"'KRCC1'",286,293,256,278.333333333333,{"$nulls":4},"GO:0005622///intracellular","GO:0002039///p53 binding+++GO:0003723///RNA binding","GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator","lysine rich coiled-coil 1","[KRCC1_HUMAN|Reviewed]RecName: Full=Lysine-rich coiled-coil protein 1; AltName: Full=Cryptogenic hepatitis-binding protein 2;+++[A0A024R5P4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW77082.1};"]
[51341,"'ZBTB7A'",2110,2370,2034,2171.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035861///site of double-strand break+++GO:0070418///DNA-dependent protein kinase complex+++GO:0016581///NuRD complex","GO:0033613///activating transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0050681///androgen receptor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046332///SMAD binding+++GO:0001222///transcription corepressor binding+++GO:0035035///histone acetyltransferase binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity","GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:2000677///regulation of transcription regulatory region DNA binding+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0034504///protein localization to nucleus+++GO:0006351///transcription, DNA-templated+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0042981///regulation of apoptotic process+++GO:0006325///chromatin organization+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0097680///double-strand break repair via classical nonhomologous end joining+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0043249///erythrocyte maturation+++GO:0060766///negative regulation of androgen receptor signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045444///fat cell differentiation+++GO:0007275///multicellular organism development+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0006338///chromatin remodeling+++GO:0030183///B cell differentiation+++GO:0006110///regulation of glycolytic process","zinc finger and BTB domain containing 7A","[ZBT7A_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 7A {ECO:0000305}; AltName: Full=Factor binding IST protein 1 {ECO:0000303|PubMed:9973611}; Short=FBI-1 {ECO:0000303|PubMed:9973611}; AltName: Full=Factor that binds to inducer of short transcripts protein 1; AltName: Full=HIV-1 1st-binding protein 1; AltName: Full=Leukemia/lymphoma-related factor {ECO:0000303|PubMed:9927193}; AltName: Full=POZ and Krueppel erythroid myeloid ontogenic factor {ECO:0000303|PubMed:15662416}; Short=POK erythroid myeloid ontogenic factor {ECO:0000303|PubMed:15662416}; Short=Pokemon {ECO:0000303|PubMed:15662416}; Short=Pokemon 1 {ECO:0000303|PubMed:17595526}; AltName: Full=TTF-I-interacting peptide 21 {ECO:0000312|EMBL:AAB58414.1}; Short=TIP21 {ECO:0000312|EMBL:AAB58414.1}; AltName: Full=Zinc finger protein 857A;+++[L8E8Q6_HUMAN|Unreviewed]SubName: Full=Alternative protein ZBTB7A {ECO:0000313|EMBL:CCQ43524.1};+++[Q8TB76_HUMAN|Unreviewed]SubName: Full=ZBTB7A protein {ECO:0000313|EMBL:AAH19108.1}; SubName: Full=Zinc finger and BTB domain containing 7A, isoform CRA_a {ECO:0000313|EMBL:EAW69266.1};"]
[51365,"'PLA1A'",72,117,107,98.6666666666667,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0002080///acrosomal membrane","GO:0052689///carboxylic ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0008970///phospholipase A1 activity","GO:0016042///lipid catabolic process+++GO:0006629///lipid metabolic process+++GO:0006658///phosphatidylserine metabolic process+++GO:0036150///phosphatidylserine acyl-chain remodeling","phospholipase A1 member A","[PLA1A_HUMAN|Reviewed]RecName: Full=Phospholipase A1 member A; EC=3.1.1.-; AltName: Full=Phosphatidylserine-specific phospholipase A1; Short=PS-PLA1; Flags: Precursor;+++[G5E9W0_HUMAN|Unreviewed]SubName: Full=Phospholipase A1 member A, isoform CRA_b {ECO:0000313|EMBL:EAW79558.1};+++[H7C4H1_HUMAN|Unreviewed]SubName: Full=Phospholipase A1 member A {ECO:0000313|Ensembl:ENSP00000417295}; Flags: Fragment;"]
[51384,"'WNT16'",3,1,0,1.33333333333333,"05165///Human papillomavirus infection+++05225///Hepatocellular carcinoma+++05217///Basal cell carcinoma+++05224///Breast cancer+++05166///HTLV-I infection+++04916///Melanogenesis+++04310///Wnt signaling pathway+++05200///Pathways in cancer+++05226///Gastric cancer+++04934///Cushing's syndrome+++05202///Transcriptional misregulation in cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer+++04390///Hippo signaling pathway+++04150///mTOR signaling pathway",null,"M00677///Wnt signaling",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding","GO:0030216///keratinocyte differentiation+++GO:0090399///replicative senescence+++GO:0060548///negative regulation of cell death+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0046849///bone remodeling+++GO:0046330///positive regulation of JNK cascade+++GO:0007275///multicellular organism development+++GO:0090403///oxidative stress-induced premature senescence+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0010628///positive regulation of gene expression+++GO:0043616///keratinocyte proliferation+++GO:0003408///optic cup formation involved in camera-type eye development+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0045165///cell fate commitment","Wnt family member 16","[WNT16_HUMAN|Reviewed]RecName: Full=Protein Wnt-16; Flags: Precursor;+++[A4D0W7_HUMAN|Unreviewed]RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};+++[A4D0W8_HUMAN|Unreviewed]RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};+++[A8W4W5_HUMAN|Unreviewed]RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500}; Flags: Fragment;+++[E9PH60_HUMAN|Unreviewed]RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};+++[L8ECG6_HUMAN|Unreviewed]SubName: Full=Alternative protein WNT16 {ECO:0000313|EMBL:CCQ43532.1};"]
[51429,"'SNX9'",687,729,659,691.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005623///cell+++GO:0001726///ruffle+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0030136///clathrin-coated vesicle+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network","GO:0031625///ubiquitin protein ligase binding+++GO:0035091///phosphatidylinositol binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0042803///protein homodimerization activity+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0071933///Arp2/3 complex binding","GO:0032461///positive regulation of protein oligomerization+++GO:0043547///positive regulation of GTPase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0000278///mitotic cell cycle+++GO:0006886///intracellular protein transport+++GO:0036089///cleavage furrow formation+++GO:0006897///endocytosis+++GO:0016197///endosomal transport+++GO:0000281///mitotic cytokinesis+++GO:0051301///cell division+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0006898///receptor-mediated endocytosis+++GO:0007049///cell cycle+++GO:0060988///lipid tube assembly+++GO:0015031///protein transport+++GO:0097320///plasma membrane tubulation+++GO:0061024///membrane organization","sorting nexin 9","[SNX9_HUMAN|Reviewed]RecName: Full=Sorting nexin-9; AltName: Full=SH3 and PX domain-containing protein 1; Short=Protein SDP1; AltName: Full=SH3 and PX domain-containing protein 3A;+++[A0A087WVE4_HUMAN|Unreviewed]SubName: Full=Sorting nexin-9 {ECO:0000313|Ensembl:ENSP00000479382}; Flags: Fragment;+++[A0A087WZW2_HUMAN|Unreviewed]SubName: Full=Sorting nexin-9 {ECO:0000313|Ensembl:ENSP00000482920}; Flags: Fragment;+++[O95061_HUMAN|Unreviewed]SubName: Full=WASP interactor protein {ECO:0000313|EMBL:AAD00898.2}; Flags: Fragment;"]
[51440,"'HPCAL4'",2,0,2,1.33333333333333,{"$nulls":4},"GO:0005622///intracellular","GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0008022///protein C-terminus binding+++GO:0005246///calcium channel regulator activity+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0007417///central nervous system development+++GO:0007165///signal transduction","hippocalcin like 4","[HPCL4_HUMAN|Reviewed]RecName: Full=Hippocalcin-like protein 4; Short=HLP4;+++[B4DGW9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50758, moderately similar to Hippocalcin-like protein 4 {ECO:0000313|EMBL:BAG57930.1};"]
[51493,"'RTCB'",886,867,834,862.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0005654///nucleoplasm+++GO:0072669///tRNA-splicing ligase complex+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0017166///vinculin binding+++GO:0003723///RNA binding+++GO:0003972///RNA ligase (ATP) activity+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0008452///RNA ligase activity+++GO:0016874///ligase activity","GO:0001890///placenta development+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0000971///tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate+++GO:0008033///tRNA processing+++GO:0006396///RNA processing+++GO:0001701///in utero embryonic development","RNA 2',3'-cyclic phosphate and 5'-OH ligase","[RTCB_HUMAN|Reviewed]RecName: Full=tRNA-splicing ligase RtcB homolog {ECO:0000255|HAMAP-Rule:MF_03144}; EC=6.5.1.3 {ECO:0000255|HAMAP-Rule:MF_03144, ECO:0000269|PubMed:21311021};"]
[51501,"'HIKESHI'",213,154,166,177.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0008565///protein transporter activity+++GO:0030544///Hsp70 protein binding","GO:0015031///protein transport+++GO:0006606///protein import into nucleus+++GO:0030324///lung development+++GO:0007030///Golgi organization+++GO:0034605///cellular response to heat+++GO:1900034///regulation of cellular response to heat","Hikeshi, heat shock protein nuclear import factor","[HIKES_HUMAN|Reviewed]RecName: Full=Protein Hikeshi {ECO:0000305};+++[A0A087WYW7_HUMAN|Unreviewed]SubName: Full=Protein Hikeshi {ECO:0000313|Ensembl:ENSP00000482151};+++[E9PJB2_HUMAN|Unreviewed]SubName: Full=Protein Hikeshi {ECO:0000313|Ensembl:ENSP00000433815};+++[E9PPG8_HUMAN|Unreviewed]SubName: Full=Protein Hikeshi {ECO:0000313|Ensembl:ENSP00000432699};"]
[51526,"'OSER1'",267,293,237,265.666666666667,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0030176///integral component of endoplasmic reticulum membrane",null,"GO:0022604///regulation of cell morphogenesis+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0034389///lipid droplet organization+++GO:0010866///regulation of triglyceride biosynthetic process+++GO:0035356///cellular triglyceride homeostasis+++GO:0007010///cytoskeleton organization+++GO:0030730///sequestering of triglyceride+++GO:0019915///lipid storage+++GO:0008654///phospholipid biosynthetic process","oxidative stress responsive serine rich 1","[OSER1_HUMAN|Reviewed]RecName: Full=Oxidative stress-responsive serine-rich protein 1; AltName: Full=Oxidative stress-responsive protein 1; AltName: Full=Peroxide-inducible transcript 1 protein;"]
[51560,"'RAB6B'",568,676,642,628.666666666667,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0000139///Golgi membrane+++GO:0098793///presynapse+++GO:0005829///cytosol+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0003924///GTPase activity+++GO:0031489///myosin V binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0015031///protein transport+++GO:0032482///Rab protein signal transduction+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0042147///retrograde transport, endosome to Golgi","RAB6B, member RAS oncogene family","[RAB6B_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-6B;+++[C9J0I2_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000418540};+++[C9JB90_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000417433}; Flags: Fragment;+++[C9JU14_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000419526}; Flags: Fragment;+++[J3KR73_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000419941}; Flags: Fragment;+++[Q6AZ91_HUMAN|Unreviewed]SubName: Full=RAB6B protein {ECO:0000313|EMBL:AAH78662.1};+++[Q9UL29_HUMAN|Unreviewed]SubName: Full=GTP-binding protein RAB6B {ECO:0000313|EMBL:AAF00044.1}; Flags: Fragment;"]
[51567,"'TDP2'",267,223,252,247.333333333333,null,"H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0016235///aggresome+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0004518///nuclease activity+++GO:0036317///tyrosyl-RNA phosphodiesterase activity+++GO:0003697///single-stranded DNA binding+++GO:0070260///5'-tyrosyl-DNA phosphodiesterase activity+++GO:0030145///manganese ion binding+++GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0003714///transcription corepressor activity","GO:0006281///DNA repair+++GO:0048666///neuron development+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007166///cell surface receptor signaling pathway+++GO:0006302///double-strand break repair+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0006974///cellular response to DNA damage stimulus","tyrosyl-DNA phosphodiesterase 2","[TYDP2_HUMAN|Reviewed]RecName: Full=Tyrosyl-DNA phosphodiesterase 2; Short=Tyr-DNA phosphodiesterase 2; Short=hTDP2; EC=3.1.4.-; AltName: Full=5'-tyrosyl-DNA phosphodiesterase; Short=5'-Tyr-DNA phosphodiesterase; AltName: Full=ETS1-associated protein 2; AltName: Full=ETS1-associated protein II; Short=EAPII; AltName: Full=TRAF and TNF receptor-associated protein; AltName: Full=Tyrosyl-RNA phosphodiesterase; AltName: Full=VPg unlinkase;+++[I3QNV0_HUMAN|Unreviewed]SubName: Full=Tyrosyl-DNA phosphodiesterase 2 {ECO:0000313|EMBL:AFK13123.1}; Flags: Fragment;+++[X6R5A3_HUMAN|Unreviewed]SubName: Full=TRAF and TNF receptor associated protein, isoform CRA_b {ECO:0000313|EMBL:EAW55459.1}; SubName: Full=Tyrosyl-DNA phosphodiesterase 2 {ECO:0000313|Ensembl:ENSP00000345345};"]
[5159,"'PDGFRB'",8828,9149,8064,8680.33333333333,"05166///HTLV-I infection+++04010///MAPK signaling pathway+++04072///Phospholipase D signaling pathway+++05214///Glioma+++04015///Rap1 signaling pathway+++05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++05230///Central carbon metabolism in cancer+++04510///Focal adhesion+++05165///Human papillomavirus infection+++05206///MicroRNAs in cancer+++05215///Prostate cancer+++04810///Regulation of actin cytoskeleton+++05218///Melanoma+++04540///Gap junction+++05231///Choline metabolism in cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++04630///Jak-STAT signaling pathway+++04020///Calcium signaling pathway+++04014///Ras signaling pathway","H00042///Glioma+++H01574///Familial idiopathic basal ganglia calcification+++H01910///Infantile myofibromatosis","M00177///Ribosome, eukaryotes",null,"GO:0005925///focal adhesion+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0043202///lysosomal lumen","GO:0005017///platelet-derived growth factor-activated receptor activity+++GO:0038085///vascular endothelial growth factor binding+++GO:0019899///enzyme binding+++GO:0000166///nucleotide binding+++GO:0019901///protein kinase binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0005524///ATP binding+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0005019///platelet-derived growth factor beta-receptor activity+++GO:0004992///platelet activating factor receptor activity+++GO:0005102///signaling receptor binding+++GO:0004672///protein kinase activity+++GO:0048407///platelet-derived growth factor binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity","GO:0006024///glycosaminoglycan biosynthetic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0042542///response to hydrogen peroxide+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0007165///signal transduction+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0009968///negative regulation of signal transduction+++GO:0072277///metanephric glomerular capillary formation+++GO:0014070///response to organic cyclic compound+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050921///positive regulation of chemotaxis+++GO:0030154///cell differentiation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0043065///positive regulation of apoptotic process+++GO:0035789///metanephric mesenchymal cell migration+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0072278///metanephric comma-shaped body morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0042060///wound healing+++GO:0046777///protein autophosphorylation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0090280///positive regulation of calcium ion import+++GO:0035556///intracellular signal transduction+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0032526///response to retinoic acid+++GO:0032355///response to estradiol+++GO:0034405///response to fluid shear stress+++GO:0009636///response to toxic substance+++GO:0046488///phosphatidylinositol metabolic process+++GO:0038091///positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:0016310///phosphorylation+++GO:0060326///cell chemotaxis+++GO:0006935///chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:2000491///positive regulation of hepatic stellate cell activation+++GO:0072075///metanephric mesenchyme development+++GO:0035793///positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway+++GO:0055003///cardiac myofibril assembly+++GO:0010863///positive regulation of phospholipase C activity+++GO:0035909///aorta morphogenesis+++GO:0048839///inner ear development+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0043627///response to estrogen+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0072262///metanephric glomerular mesangial cell proliferation involved in metanephros development+++GO:0060981///cell migration involved in coronary angiogenesis+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0007275///multicellular organism development+++GO:0072284///metanephric S-shaped body morphogenesis+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0035441///cell migration involved in vasculogenesis+++GO:0008584///male gonad development+++GO:0035791///platelet-derived growth factor receptor-beta signaling pathway+++GO:0061298///retina vasculature development in camera-type eye+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0072275///metanephric glomerulus morphogenesis+++GO:0007568///aging+++GO:0033993///response to lipid+++GO:0055093///response to hyperoxia+++GO:0016477///cell migration+++GO:0000165///MAPK cascade+++GO:0071670///smooth muscle cell chemotaxis+++GO:0060437///lung growth","platelet derived growth factor receptor beta","[PGFRB_HUMAN|Reviewed]RecName: Full=Platelet-derived growth factor receptor beta; Short=PDGF-R-beta; Short=PDGFR-beta; EC=2.7.10.1; AltName: Full=Beta platelet-derived growth factor receptor; AltName: Full=Beta-type platelet-derived growth factor receptor; AltName: Full=CD140 antigen-like family member B; AltName: Full=Platelet-derived growth factor receptor 1; Short=PDGFR-1; AltName: CD_antigen=CD140b; Flags: Precursor;+++[E5RH16_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor receptor beta {ECO:0000313|Ensembl:ENSP00000430026};+++[E5RII0_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor receptor beta {ECO:0000313|Ensembl:ENSP00000430715}; Flags: Fragment;+++[E5RJ14_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor receptor beta {ECO:0000313|Ensembl:ENSP00000429218}; Flags: Fragment;+++[Q59F04_HUMAN|Unreviewed]RecName: Full=Receptor protein-tyrosine kinase {ECO:0000256|SAAS:SAAS00602636}; EC=2.7.10.1 {ECO:0000256|SAAS:SAAS00602636}; Flags: Fragment;"]
[5162,"'PDHB'",1076,940,1018,1011.33333333333,"01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01200///Carbon metabolism+++04066///HIF-1 signaling pathway+++00020///Citrate cycle (TCA cycle)+++01120///Microbial metabolism in diverse environments+++00620///Pyruvate metabolism+++04922///Glucagon signaling pathway+++00010///Glycolysis / Gluconeogenesis+++01110///Biosynthesis of secondary metabolites+++05230///Central carbon metabolism in cancer","H00072///Pyruvate dehydrogenase complex deficiency+++H01998///Pyruvate dehydrogenase E1-beta deficiency","M00307///Pyruvate oxidation, pyruvate => acetyl-CoA","R00209///pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate   Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H++++R00014///pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)   Pyruvate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2+++R03270///2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate+++R01699///pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)   Pyruvate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2","GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0045254///pyruvate dehydrogenase complex+++GO:0005654///nucleoplasm+++GO:0005759///mitochondrial matrix","GO:0005515///protein binding+++GO:0034604///pyruvate dehydrogenase (NAD+) activity+++GO:0003824///catalytic activity+++GO:0004739///pyruvate dehydrogenase (acetyl-transferring) activity+++GO:0004738///pyruvate dehydrogenase activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0006086///acetyl-CoA biosynthetic process from pyruvate+++GO:0006099///tricarboxylic acid cycle+++GO:0006006///glucose metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate","pyruvate dehydrogenase E1 beta subunit","[ODPB_HUMAN|Reviewed]RecName: Full=Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; Short=PDHE1-B; EC=1.2.4.1; Flags: Precursor;+++[C9J634_HUMAN|Unreviewed]SubName: Full=Pyruvate dehydrogenase E1 component subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000418448};+++[F8WF02_HUMAN|Unreviewed]SubName: Full=Pyruvate dehydrogenase E1 component subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000419580};"]
[51646,"'YPEL5'",835,633,641,703,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030496///midbody+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:1904724///tertiary granule lumen+++GO:0005856///cytoskeleton+++GO:0005576///extracellular region+++GO:0097431///mitotic spindle pole+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005815///microtubule organizing center+++GO:0000922///spindle pole+++GO:0005813///centrosome","GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0008283///cell proliferation+++GO:0043312///neutrophil degranulation","yippee like 5","[YPEL5_HUMAN|Reviewed]RecName: Full=Protein yippee-like 5;"]
[51661,"'FKBP7'",189,182,202,191,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0005783///endoplasmic reticulum","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0000413///protein peptidyl-prolyl isomerization","FK506 binding protein 7","[FKBP7_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP7; Short=PPIase FKBP7; EC=5.2.1.8; AltName: Full=23 kDa FK506-binding protein; Short=23 kDa FKBP; Short=FKBP-23; AltName: Full=FK506-binding protein 7; Short=FKBP-7; AltName: Full=Rotamase; Flags: Precursor;+++[D3DPF8_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};+++[F8WBF2_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase FKBP7 {ECO:0000313|Ensembl:ENSP00000398869};+++[F8WCU2_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase FKBP7 {ECO:0000313|Ensembl:ENSP00000403801};+++[F8WE12_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};+++[H7BZJ4_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277}; Flags: Fragment;"]
[51693,"'TRAPPC2L'",735,838,718,763.666666666667,null,"H00760///Spondyloepiphyseal dysplasia tarda",null,null,"GO:0030008///TRAPP complex+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000139///Golgi membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0051259///protein complex oligomerization","trafficking protein particle complex 2 like","[TPC2L_HUMAN|Reviewed]RecName: Full=Trafficking protein particle complex subunit 2-like protein;+++[A0A0B4J286_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000455235};+++[A0A0B4J294_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000457728};+++[H3BP13_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000455100};+++[H3BPE0_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000455273};+++[H3BPN3_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000455392};+++[H3BPS1_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000455447};+++[H3BQQ8_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000455892};+++[H3BUK6_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 2-like protein {ECO:0000313|Ensembl:ENSP00000457684};"]
[51719,"'CAB39'",691,494,548,577.666666666667,"04152///AMPK signaling pathway+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:1904813///ficolin-1-rich granule lumen+++GO:0034774///secretory granule lumen+++GO:0070062///extracellular exosome+++GO:1902554///serine/threonine protein kinase complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex","GO:0030295///protein kinase activator activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0019900///kinase binding+++GO:0005515///protein binding","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0071476///cellular hypotonic response+++GO:0018105///peptidyl-serine phosphorylation+++GO:0023014///signal transduction by protein phosphorylation+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:0035556///intracellular signal transduction+++GO:0051291///protein heterooligomerization+++GO:0006468///protein phosphorylation+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:0007050///cell cycle arrest+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0043312///neutrophil degranulation","calcium binding protein 39","[CAB39_HUMAN|Reviewed]RecName: Full=Calcium-binding protein 39; AltName: Full=MO25alpha; AltName: Full=Protein Mo25;+++[A0A024R496_HUMAN|Unreviewed]SubName: Full=Calcium binding protein 39, isoform CRA_a {ECO:0000313|EMBL:EAW70933.1};+++[A0A087X0K1_HUMAN|Unreviewed]SubName: Full=Calcium-binding protein 39 {ECO:0000313|Ensembl:ENSP00000483459};+++[Q53RN7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MO25 {ECO:0000313|EMBL:AAY14829.1}; Flags: Fragment;"]
[51752,"'ERAP1'",595.7,571,537,567.9,"04614///Renin-angiotensin system+++04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0004175///endopeptidase activity+++GO:0042277///peptide binding+++GO:0005138///interleukin-6 receptor binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008235///metalloexopeptidase activity+++GO:0008233///peptidase activity+++GO:0004177///aminopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0005151///interleukin-1, type II receptor binding+++GO:0070006///metalloaminopeptidase activity+++GO:0005515///protein binding","GO:0001525///angiogenesis+++GO:0045444///fat cell differentiation+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0043171///peptide catabolic process+++GO:0045766///positive regulation of angiogenesis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0002376///immune system process+++GO:0008217///regulation of blood pressure+++GO:0006508///proteolysis+++GO:0045088///regulation of innate immune response+++GO:0009617///response to bacterium+++GO:0002250///adaptive immune response+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I","endoplasmic reticulum aminopeptidase 1","[ERAP1_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum aminopeptidase 1; EC=3.4.11.-; AltName: Full=ARTS-1; AltName: Full=Adipocyte-derived leucine aminopeptidase; Short=A-LAP; AltName: Full=Aminopeptidase PILS; AltName: Full=Puromycin-insensitive leucyl-specific aminopeptidase; Short=PILS-AP; AltName: Full=Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator;+++[A0A024RAR8_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040};+++[A0A075BSP6_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040};+++[A0A075BTL2_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase 1 delta-Exon-11 isoform {ECO:0000313|EMBL:AGR86647.1};+++[A0A075BV59_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase 1 delta-Exon-13 isoform {ECO:0000313|EMBL:AGR86648.1};+++[A0A075BW43_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase 1 delta-Exon-14 isoform {ECO:0000313|EMBL:AGR86649.1};+++[A0A0A7E6D4_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E6D8_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E6I2_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E6J5_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E6K0_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E6P0_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E6P4_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E6P9_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E7S5_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E7T3_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E7W5_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E7W9_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A0A7E7X3_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040}; Flags: Fragment;+++[A0A1D5RMR7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase 1 {ECO:0000313|Ensembl:ENSP00000422631}; Flags: Fragment;+++[A0A1S6KJG9_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase 1 {ECO:0000313|EMBL:AQT03317.1}; Flags: Fragment;+++[A0A2I6QG18_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase-1 {ECO:0000313|EMBL:AUN35149.1}; Flags: Fragment;+++[D6RAL9_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase 1 {ECO:0000313|Ensembl:ENSP00000421697}; Flags: Fragment;+++[H0Y9X5_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum aminopeptidase 1 {ECO:0000313|Ensembl:ENSP00000425381}; Flags: Fragment;"]
[5178,"'PEG3'",102.56,124,99.56,108.706666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005776///autophagosome","GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006915///apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II","paternally expressed 3","[PEG3_HUMAN|Reviewed]RecName: Full=Paternally-expressed gene 3 protein; AltName: Full=Zinc finger and SCAN domain-containing protein 24;+++[B9EG68_HUMAN|Unreviewed]SubName: Full=PEG3 protein {ECO:0000313|EMBL:AAI36269.1};+++[L8EAH8_HUMAN|Unreviewed]SubName: Full=Alternative protein PEG3 {ECO:0000313|EMBL:CCQ43348.1};+++[M0QXG1_HUMAN|Unreviewed]SubName: Full=Paternally-expressed gene 3 protein {ECO:0000313|Ensembl:ENSP00000469144}; Flags: Fragment;+++[M0QZD4_HUMAN|Unreviewed]SubName: Full=Paternally-expressed gene 3 protein {ECO:0000313|Ensembl:ENSP00000470467}; Flags: Fragment;+++[Q96Q96_HUMAN|Unreviewed]SubName: Full=KIAA0287 protein {ECO:0000313|EMBL:BAA22956.2}; Flags: Fragment;"]
[5193,"'PEX12'",211,207,198,205.333333333333,"04146///Peroxisome","H01342///Zellweger syndrome (ZS)+++H00205///Peroxisome biogenesis disorder",null,null,"GO:1990429///peroxisomal importomer complex+++GO:0005777///peroxisome+++GO:0005779///integral component of peroxisomal membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005778///peroxisomal membrane","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding","GO:0016558///protein import into peroxisome matrix+++GO:0006625///protein targeting to peroxisome+++GO:0007031///peroxisome organization+++GO:0016567///protein ubiquitination+++GO:0006513///protein monoubiquitination","peroxisomal biogenesis factor 12","[PEX12_HUMAN|Reviewed]RecName: Full=Peroxisome assembly protein 12; AltName: Full=Peroxin-12; AltName: Full=Peroxisome assembly factor 3; Short=PAF-3;+++[A0A075B773_HUMAN|Unreviewed]RecName: Full=Peroxisome assembly protein 12 {ECO:0000256|PIRNR:PIRNR038074}; AltName: Full=Peroxin-12 {ECO:0000256|PIRNR:PIRNR038074};+++[A0PJ54_HUMAN|Unreviewed]SubName: Full=PEX12 protein {ECO:0000313|EMBL:AAH15751.1}; Flags: Fragment;+++[K7ELY8_HUMAN|Unreviewed]SubName: Full=Peroxisome assembly protein 12 {ECO:0000313|Ensembl:ENSP00000466280}; Flags: Fragment;"]
[5209,"'PFKFB3'",397,350,366,371,"04152///AMPK signaling pathway+++04066///HIF-1 signaling pathway+++00051///Fructose and mannose metabolism","H00408///Type I diabetes mellitus",null,"R02731///D-Fructose-2,6-bisphosphate 2-phosphohydrolase   beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate","GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0003824///catalytic activity+++GO:0004331///fructose-2,6-bisphosphate 2-phosphatase activity+++GO:0003873///6-phosphofructo-2-kinase activity+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity","GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0045821///positive regulation of glycolytic process+++GO:0046835///carbohydrate phosphorylation+++GO:0008152///metabolic process+++GO:0006000///fructose metabolic process+++GO:0007420///brain development+++GO:0006003///fructose 2,6-bisphosphate metabolic process","6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3","[F263_HUMAN|Reviewed]RecName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; Short=6PF-2-K/Fru-2,6-P2ase 3; Short=PFK/FBPase 3; AltName: Full=6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; AltName: Full=Renal carcinoma antigen NY-REN-56; AltName: Full=iPFK-2; Includes: RecName: Full=6-phosphofructo-2-kinase; EC=2.7.1.105; Includes: RecName: Full=Fructose-2,6-bisphosphatase; EC=3.1.3.46;+++[A0A1W2PNV9_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000491095}; Flags: Fragment;+++[A0A1W2PR17_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000492001};+++[B7Z8A0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54727, highly similar to 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 {ECO:0000313|EMBL:BAH13886.1};+++[F2Z2I2_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000434628};+++[H0Y483_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000390285}; Flags: Fragment;+++[H0YDV0_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000434342}; Flags: Fragment;+++[Q5VX20_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000369111};+++[Q5W015_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000369105};+++[Q9BQU1_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase {ECO:0000313|EMBL:CAC34794.1}; EC=2.7.1.105 {ECO:0000313|EMBL:CAC34794.1}; SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000404995}; Flags: Fragment;+++[Q9BQU2_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase {ECO:0000313|EMBL:CAC34793.1}; EC=2.7.1.105 {ECO:0000313|EMBL:CAC34793.1}; Flags: Fragment;+++[Q9BQU3_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase {ECO:0000313|EMBL:CAC34792.1}; EC=2.7.1.105 {ECO:0000313|EMBL:CAC34792.1}; Flags: Fragment;+++[Q9H178_HUMAN|Unreviewed]SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase {ECO:0000313|EMBL:CAC20460.1}; EC=2.7.1.105 {ECO:0000313|EMBL:CAC20460.1}; SubName: Full=6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 {ECO:0000313|Ensembl:ENSP00000416677}; Flags: Fragment;+++[Q9UBT0_HUMAN|Unreviewed]SubName: Full=Inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase {ECO:0000313|EMBL:AAD23989.1}; Flags: Fragment;"]
[5230,"'PGK1'",5909,5165,5417,5497,"00710///Carbon fixation in photosynthetic organisms+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++01230///Biosynthesis of amino acids+++00010///Glycolysis / Gluconeogenesis+++01120///Microbial metabolism in diverse environments+++01200///Carbon metabolism","H00664///Anemia due to disorders of glycolytic enzymes","M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate+++M00166///Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P+++M00002///Glycolysis, core module involving three-carbon compounds+++M00308///Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P+++M00003///Gluconeogenesis, oxaloacetate => fructose-6P+++M00552///D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P+++M00165///Reductive pentose phosphate cycle (Calvin cycle)","R01512///ATP:3-phospho-D-glycerate 1-phosphotransferase   ATP + 3-Phospho-D-glycerate <=> ADP + 3-Phospho-D-glyceroyl phosphate","GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0045121///membrane raft+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0004618///phosphoglycerate kinase activity+++GO:0047134///protein-disulfide reductase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0043531///ADP binding+++GO:0000166///nucleotide binding","GO:0007525///somatic muscle development+++GO:0031639///plasminogen activation+++GO:0071456///cellular response to hypoxia+++GO:0030855///epithelial cell differentiation+++GO:0016525///negative regulation of angiogenesis+++GO:0006094///gluconeogenesis+++GO:0046716///muscle cell cellular homeostasis+++GO:0061621///canonical glycolysis+++GO:0016310///phosphorylation+++GO:0007520///myoblast fusion+++GO:0007268///chemical synaptic transmission+++GO:0006096///glycolytic process","phosphoglycerate kinase 1","[PGK1_HUMAN|Reviewed]RecName: Full=Phosphoglycerate kinase 1; EC=2.7.2.3; AltName: Full=Cell migration-inducing gene 10 protein; AltName: Full=Primer recognition protein 2; Short=PRP 2;+++[V9HWF4_HUMAN|Unreviewed]RecName: Full=Phosphoglycerate kinase {ECO:0000256|RuleBase:RU000532}; EC=2.7.2.3 {ECO:0000256|RuleBase:RU000532};"]
[5256,"'PHKA2'",446,517,439,467.333333333333,"04922///Glucagon signaling pathway+++04910///Insulin signaling pathway+++04020///Calcium signaling pathway","H01762///Muscle glycogen storage disease+++H01760///Hepatic glycogen storage disease+++H01948///Glycogen storage disease type IX+++H00069///Glycogen storage diseases (GSD)",null,null,"GO:0005829///cytosol+++GO:0005964///phosphorylase kinase complex+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0016740///transferase activity+++GO:0004689///phosphorylase kinase activity+++GO:0003824///catalytic activity+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding","GO:0016310///phosphorylation+++GO:0005977///glycogen metabolic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0005975///carbohydrate metabolic process+++GO:0006468///protein phosphorylation+++GO:0006464///cellular protein modification process","phosphorylase kinase regulatory subunit alpha 2","[KPB2_HUMAN|Reviewed]RecName: Full=Phosphorylase b kinase regulatory subunit alpha, liver isoform; Short=Phosphorylase kinase alpha L subunit;+++[O60912_HUMAN|Unreviewed]SubName: Full=Phosphorylase kinase alpha-subunit {ECO:0000313|EMBL:CAA75420.1}; EC=2.7.1.38 {ECO:0000313|EMBL:CAA75420.1}; Flags: Fragment;"]
[5276,"'SERPINI2'",5,0,0,1.66666666666667,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome","GO:0030414///peptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding","GO:0010951///negative regulation of endopeptidase activity+++GO:0030155///regulation of cell adhesion+++GO:0010466///negative regulation of peptidase activity","serpin family I member 2","[SPI2_HUMAN|Reviewed]RecName: Full=Serpin I2; AltName: Full=Myoepithelium-derived serine protease inhibitor; AltName: Full=Pancpin; AltName: Full=Pancreas-specific protein TSA2004; AltName: Full=Peptidase inhibitor 14; Short=PI-14; Flags: Precursor;+++[A0A0C4DGW9_HUMAN|Unreviewed]SubName: Full=Serpin I2 {ECO:0000313|Ensembl:ENSP00000481699};+++[B4DDY9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56490, highly similar to Serpin I2 {ECO:0000313|EMBL:BAG56900.1};+++[C9J7N5_HUMAN|Unreviewed]SubName: Full=Serpin I2 {ECO:0000313|Ensembl:ENSP00000417752}; Flags: Fragment;+++[C9JWE1_HUMAN|Unreviewed]SubName: Full=Serpin I2 {ECO:0000313|Ensembl:ENSP00000419255}; Flags: Fragment;"]
[5298,"'PI4KB'",1457,1612,1369,1479.33333333333,"00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways",null,"M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R03361///ATP:1-Phosphatidyl-1D-myo-inositol 4-phosphotransferase   ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate","GO:0048471///perinuclear region of cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0012505///endomembrane system","GO:0004430///1-phosphatidylinositol 4-kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0071889///14-3-3 protein binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding","GO:0006661///phosphatidylinositol biosynthetic process+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0006898///receptor-mediated endocytosis","phosphatidylinositol 4-kinase beta","[PI4KB_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 4-kinase beta; Short=PI4K-beta; Short=PI4Kbeta; Short=PtdIns 4-kinase beta; EC=2.7.1.67; AltName: Full=NPIK; AltName: Full=PI4K92;+++[A0A0A0MSL0_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-kinase beta {ECO:0000313|Ensembl:ENSP00000394719}; Flags: Fragment;+++[A0A0B4J1S8_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-kinase beta {ECO:0000313|Ensembl:ENSP00000357869};+++[A6PVV8_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-kinase beta {ECO:0000313|Ensembl:ENSP00000410974}; Flags: Fragment;+++[E9PL47_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-kinase beta {ECO:0000313|Ensembl:ENSP00000431501}; Flags: Fragment;+++[F8W860_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-kinase beta {ECO:0000313|Ensembl:ENSP00000413599}; Flags: Fragment;+++[H0Y4F8_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-kinase beta {ECO:0000313|Ensembl:ENSP00000391546}; Flags: Fragment;+++[H0YCW3_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-kinase beta {ECO:0000313|Ensembl:ENSP00000432426}; Flags: Fragment;"]
[5314,"'PKHD1'",4,10,2,5.33333333333333,null,"H00542///Polycystic kidney disease+++H01728///Potter syndrome",null,null,"GO:0005737///cytoplasm+++GO:0031362///anchored component of external side of plasma membrane+++GO:0005819///spindle+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0005694///chromosome+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0036064///ciliary basal body+++GO:0005813///centrosome+++GO:0000775///chromosome, centromeric region+++GO:0005929///cilium+++GO:0005856///cytoskeleton+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0072686///mitotic spindle+++GO:0048471///perinuclear region of cytoplasm","GO:0038023///signaling receptor activity+++GO:0005515///protein binding","GO:0051898///negative regulation of protein kinase B signaling+++GO:0032006///regulation of TOR signaling+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0001822///kidney development+++GO:0008284///positive regulation of cell proliferation+++GO:0051271///negative regulation of cellular component movement+++GO:0042592///homeostatic process+++GO:0043066///negative regulation of apoptotic process+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0010824///regulation of centrosome duplication+++GO:0006874///cellular calcium ion homeostasis+++GO:0060271///cilium assembly+++GO:0098609///cell-cell adhesion","PKHD1, fibrocystin/polyductin","[PKHD1_HUMAN|Reviewed]RecName: Full=Fibrocystin; AltName: Full=Polycystic kidney and hepatic disease 1 protein; AltName: Full=Polyductin; AltName: Full=Tigmin; Flags: Precursor;+++[L0R5C3_HUMAN|Unreviewed]SubName: Full=Alternative protein PKHD1 {ECO:0000313|EMBL:CCO13789.1};"]
[53339,"'BTBD1'",572,550,559,560.333333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0000932///P-body","GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0030154///cell differentiation+++GO:0043393///regulation of protein binding+++GO:0007517///muscle organ development+++GO:0016567///protein ubiquitination+++GO:0022008///neurogenesis","BTB domain containing 1","[BTBD1_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein 1; AltName: Full=Hepatitis C virus NS5A-transactivated protein 8; Short=HCV NS5A-transactivated protein 8;+++[A0A024R224_HUMAN|Unreviewed]SubName: Full=BTB (POZ) domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW62430.1};+++[H0YL89_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000453104}; Flags: Fragment;+++[Q3ZTS5_HUMAN|Unreviewed]SubName: Full=BTB domain containing 1 {ECO:0000313|EMBL:AAQ76812.1};"]
[53354,"'PANK1'",182,196,151,176.333333333333,"00770///Pantothenate and CoA biosynthesis+++01100///Metabolic pathways","H00832///Core neuroacanthocytosis syndromes+++H00833///Neurodegeneration with brain iron accumulation (NBIA)","M00120///Coenzyme A biosynthesis, pantothenate => CoA","R03018///ATP:pantothenate 4'-phosphotransferase   ATP + Pantothenate <=> ADP + D-4'-Phosphopantothenate+++R02971///ATP:pantothenate 4'-phosphotransferase   ATP + Pantetheine <=> ADP + Pantetheine 4'-phosphate+++R04391///ATP:pantothenate 4'-phosphotransferase   ATP + N-((R)-Pantothenoyl)-L-cysteine <=> ADP + (R)-4'-Phosphopantothenoyl-L-cysteine","GO:0030118///clathrin coat+++GO:0055037///recycling endosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071944///cell periphery","GO:0004594///pantothenate kinase activity+++GO:0016301///kinase activity+++GO:0042803///protein homodimerization activity+++GO:1905502///acetyl-CoA binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity","GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation+++GO:0009108///coenzyme biosynthetic process","pantothenate kinase 1","[PANK1_HUMAN|Reviewed]RecName: Full=Pantothenate kinase 1; Short=hPanK; Short=hPanK1; EC=2.7.1.33; AltName: Full=Pantothenic acid kinase 1;"]
[5346,"'PLIN1'",2,0,0,0.666666666666667,"04714///Thermogenesis+++04923///Regulation of lipolysis in adipocytes+++04371///Apelin signaling pathway+++03320///PPAR signaling pathway","H00420///Familial partial lipodystrophy (FPL)",null,null,"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0016021///integral component of membrane+++GO:0005829///cytosol","GO:0008289///lipid binding","GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process","perilipin 1","[PLIN1_HUMAN|Reviewed]RecName: Full=Perilipin-1; AltName: Full=Lipid droplet-associated protein;+++[H0YM16_HUMAN|Unreviewed]SubName: Full=Perilipin-1 {ECO:0000313|Ensembl:ENSP00000453426}; Flags: Fragment;"]
[5352,"'PLOD2'",3295,2476,2658,2809.66666666667,"00310///Lysine degradation","H00514///Bruck syndrome",null,"R03376///[procollagen]-L-lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)   Protein lysine + 2-Oxoglutarate + Oxygen <=> Procollagen 5-hydroxy-L-lysine + Succinate + CO2","GO:0070062///extracellular exosome+++GO:0030867///rough endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0046872///metal ion binding+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0008475///procollagen-lysine 5-dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0005506///iron ion binding+++GO:0033823///procollagen glucosyltransferase activity+++GO:0031418///L-ascorbic acid binding+++GO:0051213///dioxygenase activity","GO:0001666///response to hypoxia+++GO:0032963///collagen metabolic process+++GO:0046947///hydroxylysine biosynthetic process+++GO:0030199///collagen fibril organization+++GO:0006493///protein O-linked glycosylation+++GO:0006464///cellular protein modification process+++GO:0055114///oxidation-reduction process+++GO:0017185///peptidyl-lysine hydroxylation","procollagen-lysine,2-oxoglutarate 5-dioxygenase 2","[PLOD2_HUMAN|Reviewed]RecName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; EC=1.14.11.4 {ECO:0000250|UniProtKB:P24802}; AltName: Full=Lysyl hydroxylase 2; Short=LH2; Flags: Precursor;+++[C9JXZ0_HUMAN|Unreviewed]SubName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 {ECO:0000313|Ensembl:ENSP00000419963}; Flags: Fragment;+++[E7ETU9_HUMAN|Unreviewed]SubName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 {ECO:0000313|Ensembl:ENSP00000420094};+++[F8WEW3_HUMAN|Unreviewed]SubName: Full=Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 {ECO:0000313|Ensembl:ENSP00000419880};+++[Q96AR9_HUMAN|Unreviewed]SubName: Full=PLOD2 protein {ECO:0000313|EMBL:AAH16834.1}; Flags: Fragment;+++[Q96QU5_HUMAN|Unreviewed]SubName: Full=Lysyl hydroxylase 2 {ECO:0000313|EMBL:AAK20119.1}; Flags: Fragment;"]
[5375,"'PMP2'",6,2,1,3,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath","GO:0015485///cholesterol binding+++GO:0008289///lipid binding+++GO:0005504///fatty acid binding+++GO:0005515///protein binding","GO:0061024///membrane organization","peripheral myelin protein 2","[MYP2_HUMAN|Reviewed]RecName: Full=Myelin P2 protein; AltName: Full=Peripheral myelin protein 2;+++[E5RH45_HUMAN|Unreviewed]SubName: Full=Myelin P2 protein {ECO:0000313|Ensembl:ENSP00000429917};"]
[53832,"'IL20RA'",24,31,26,27,"04060///Cytokine-cytokine receptor interaction+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0042015///interleukin-20 binding","GO:0045124///regulation of bone resorption+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0019221///cytokine-mediated signaling pathway","interleukin 20 receptor subunit alpha","[I20RA_HUMAN|Reviewed]RecName: Full=Interleukin-20 receptor subunit alpha; Short=IL-20 receptor subunit alpha; Short=IL-20R-alpha; Short=IL-20RA; AltName: Full=Cytokine receptor class-II member 8; AltName: Full=Cytokine receptor family 2 member 8; Short=CRF2-8; AltName: Full=IL-20R1; AltName: Full=ZcytoR7; Flags: Precursor;+++[A0A0U1RQS0_HUMAN|Unreviewed]SubName: Full=Interleukin-20 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000489141};+++[A0A0U1RQU9_HUMAN|Unreviewed]SubName: Full=Interleukin-20 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000489177}; Flags: Fragment;+++[A0A0U1RRA1_HUMAN|Unreviewed]SubName: Full=Interleukin-20 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000489419}; Flags: Fragment;+++[L8E9L9_HUMAN|Unreviewed]SubName: Full=Alternative protein IL20RA {ECO:0000313|EMBL:CCQ43436.1};+++[Q96SH7_HUMAN|Unreviewed]SubName: Full=Interleukin 20 receptor, alpha, isoform CRA_b {ECO:0000313|EMBL:EAW47937.1}; SubName: Full=Interleukin-20 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000356720};"]
[540,"'ATP7B'",298,294,269,287,"01524///Platinum drug resistance+++04016///MAPK signaling pathway - plant","H00856///Distal hereditary motor neuropathies (dHMN)+++H00210///Wilson disease+++H00209///Menkes syndrome+++H01859///Occipital horn syndrome+++H00455///Spinal muscular atrophy (SMA)",null,"R00086///ATP phosphohydrolase   ATP + H2O <=> ADP + Orthophosphate","GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane+++GO:0005770///late endosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0031410///cytoplasmic vesicle+++GO:0005887///integral component of plasma membrane+++GO:0005768///endosome+++GO:0005739///mitochondrion+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0004008///copper-exporting ATPase activity+++GO:0005375///copper ion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0005507///copper ion binding+++GO:0019829///cation-transporting ATPase activity+++GO:0043682///copper-transporting ATPase activity+++GO:0046872///metal ion binding","GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0030001///metal ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0007595///lactation+++GO:0035434///copper ion transmembrane transport+++GO:0046688///response to copper ion+++GO:0034220///ion transmembrane transport+++GO:0015677///copper ion import+++GO:0051208///sequestering of calcium ion+++GO:0060003///copper ion export+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006812///cation transport+++GO:0015680///protein maturation by copper ion transfer","ATPase copper transporting beta","[ATP7B_HUMAN|Reviewed]RecName: Full=Copper-transporting ATPase 2; EC=3.6.3.54 {ECO:0000269|PubMed:22240481}; AltName: Full=Copper pump 2; AltName: Full=Wilson disease-associated protein; Contains: RecName: Full=WND/140 kDa {ECO:0000303|PubMed:9600907};+++[A0A024RDX3_HUMAN|Unreviewed]SubName: Full=ATPase, Cu++ transporting, beta polypeptide, isoform CRA_c {ECO:0000313|EMBL:EAX08896.1};+++[A0A0U1RQY8_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000489234};+++[A0A0U1RRG1_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000489512}; Flags: Fragment;+++[A0A2Z5ENW8_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87956.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87956.1}; Flags: Fragment;+++[A0A2Z5ENX0_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87958.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87958.1}; Flags: Fragment;+++[A0A2Z5ENX2_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87959.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87959.1}; Flags: Fragment;+++[A0A2Z5ENX4_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87957.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87957.1}; Flags: Fragment;+++[A0A2Z5ENX7_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87961.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87961.1}; Flags: Fragment;+++[A0A2Z5ENX9_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87962.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87962.1}; Flags: Fragment;+++[A0A2Z5ENY1_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87960.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87960.1}; Flags: Fragment;+++[A1YIY1_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:ABL98127.1}; Flags: Fragment;+++[A6N865_HUMAN|Unreviewed]SubName: Full=Cu++ transporting ATPase beta polypeptide {ECO:0000313|EMBL:ABR10903.1}; Flags: Fragment;+++[A6YQZ0_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide {ECO:0000313|EMBL:ABR92758.1}; Flags: Fragment;+++[A6YQZ1_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide {ECO:0000313|EMBL:ABR92759.1}; Flags: Fragment;+++[A7UDR4_HUMAN|Unreviewed]SubName: Full=ATPase 7B {ECO:0000313|EMBL:ABU46397.1}; Flags: Fragment;+++[B7ZLR2_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI43974.1};+++[B7ZLR3_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI43976.1};+++[B7ZLR4_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI43977.1}; SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000489398};+++[C0LF55_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:ACN65027.1}; EC=3.6.3.4 {ECO:0000313|EMBL:ACN65027.1}; Flags: Fragment;+++[C8BMD5_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide variant {ECO:0000313|EMBL:ACU56999.1}; EC=3.6.3.4 {ECO:0000313|EMBL:ACU56999.1}; Flags: Fragment;+++[D3KCZ0_HUMAN|Unreviewed]SubName: Full=Mutant ATP7B {ECO:0000313|EMBL:ADC29645.1}; Flags: Fragment;+++[E7ET55_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000416738};+++[F5H562_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000383221};+++[F5H748_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000393343};+++[G1FFE8_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82632.1}; Flags: Fragment;+++[G1FFE9_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82633.1}; Flags: Fragment;+++[G1FFF0_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82634.1}; Flags: Fragment;+++[G1FFF1_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82635.1}; Flags: Fragment;+++[G1FFF2_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82636.1}; Flags: Fragment;+++[G1FFF3_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82637.1}; Flags: Fragment;+++[G8FXH4_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide {ECO:0000313|EMBL:AER34938.1}; EC=3.6.3.4 {ECO:0000313|EMBL:AER34938.1}; Flags: Fragment;+++[Q17RT3_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI17201.1};+++[Q52RG2_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84215.1}; Flags: Fragment;+++[Q52RG3_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84214.1}; Flags: Fragment;+++[Q52RG4_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84213.1}; Flags: Fragment;+++[Q52RG5_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84212.1}; Flags: Fragment;+++[Q52RG6_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84211.1}; Flags: Fragment;+++[Q9GZP5_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27537.1}; Flags: Fragment;+++[Q9HBD5_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27543.1}; Flags: Fragment;+++[Q9HBD6_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27542.1}; Flags: Fragment;+++[Q9HBD7_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27540.1}; Flags: Fragment;+++[Q9HBD8_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27539.1}; Flags: Fragment;+++[Q9HBD9_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27538.1}; Flags: Fragment;"]
[54108,"'CHRAC1'",253,219,218,230,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0008622///epsilon DNA polymerase complex+++GO:0008623///CHRAC+++GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0046982///protein heterodimerization activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0016779///nucleotidyltransferase activity","GO:0071897///DNA biosynthetic process+++GO:0006338///chromatin remodeling","chromatin accessibility complex subunit 1","[CHRC1_HUMAN|Reviewed]RecName: Full=Chromatin accessibility complex protein 1; Short=CHRAC-1; AltName: Full=Chromatin accessibility complex 15 kDa protein; Short=CHRAC-15; Short=HuCHRAC15; AltName: Full=DNA polymerase epsilon subunit p15;+++[E5RGS9_HUMAN|Unreviewed]SubName: Full=Chromatin accessibility complex protein 1 {ECO:0000313|Ensembl:ENSP00000428697};+++[H0YBP8_HUMAN|Unreviewed]SubName: Full=Chromatin accessibility complex protein 1 {ECO:0000313|Ensembl:ENSP00000430003}; Flags: Fragment;+++[H0YBX4_HUMAN|Unreviewed]SubName: Full=Chromatin accessibility complex protein 1 {ECO:0000313|Ensembl:ENSP00000430484}; Flags: Fragment;"]
[54165,"'DCUN1D1'",215,182,201,199.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00624///Familial cholestasis",null,null,"GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus","GO:0032182///ubiquitin-like protein binding+++GO:0005515///protein binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0097602///cullin family protein binding","GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:2000436///positive regulation of protein neddylation+++GO:0043687///post-translational protein modification+++GO:0045116///protein neddylation","defective in cullin neddylation 1 domain containing 1","[DCNL1_HUMAN|Reviewed]RecName: Full=DCN1-like protein 1; AltName: Full=DCUN1 domain-containing protein 1; AltName: Full=Defective in cullin neddylation protein 1-like protein 1; AltName: Full=Squamous cell carcinoma-related oncogene;+++[B4DM76_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131};+++[C9J0B2_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[C9J8R4_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[C9JRU6_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[C9JUW4_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[C9JVE2_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131};+++[F8WC32_HUMAN|Unreviewed]SubName: Full=DCN1-like protein 1 {ECO:0000313|Ensembl:ENSP00000418935};"]
[54329,"'GPR85'",12,24,16,17.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","G protein-coupled receptor 85","[GPR85_HUMAN|Reviewed]RecName: Full=Probable G-protein coupled receptor 85; AltName: Full=Super conserved receptor expressed in brain 2;+++[A4D0T8_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 85 {ECO:0000313|EMBL:EAL24372.1}; SubName: Full=cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA {ECO:0000313|EMBL:BAG35481.1};+++[C9JBQ9_HUMAN|Unreviewed]SubName: Full=Probable G-protein-coupled receptor 85 {ECO:0000313|Ensembl:ENSP00000415699}; Flags: Fragment;+++[C9JDK8_HUMAN|Unreviewed]SubName: Full=Probable G-protein-coupled receptor 85 {ECO:0000313|Ensembl:ENSP00000416722}; Flags: Fragment;+++[Q8NEN2_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 85 {ECO:0000313|EMBL:AAH30577.1};"]
[5437,"'POLR2H'",204,230,239,224.333333333333,"04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++05169///Epstein-Barr virus infection+++05016///Huntington's disease+++00240///Pyrimidine metabolism+++00230///Purine metabolism+++01100///Metabolic pathways",null,"M00182///RNA polymerase I, eukaryotes+++M00180///RNA polymerase II, eukaryotes+++M00181///RNA polymerase III, eukaryotes","R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA","GO:0005666///RNA polymerase III complex+++GO:0005730///nucleolus+++GO:0005736///RNA polymerase I complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0032993///protein-DNA complex+++GO:0005665///RNA polymerase II, core complex+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0001054///RNA polymerase I activity+++GO:0003697///single-stranded DNA binding+++GO:0001055///RNA polymerase II activity+++GO:0001056///RNA polymerase III activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0016070///RNA metabolic process+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0060964///regulation of gene silencing by miRNA+++GO:0006383///transcription by RNA polymerase III+++GO:0006370///7-methylguanosine mRNA capping+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006351///transcription, DNA-templated","RNA polymerase II subunit H","[RPAB3_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC3; Short=RNA polymerases I, II, and III subunit ABC3; AltName: Full=DNA-directed RNA polymerase II subunit H; AltName: Full=DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide; AltName: Full=RPB17; AltName: Full=RPB8 homolog; Short=hRPB8;+++[C9JJJ9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC3 {ECO:0000313|Ensembl:ENSP00000403728}; Flags: Fragment;+++[C9JLU1_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC3 {ECO:0000313|Ensembl:ENSP00000409065}; Flags: Fragment;"]
[54443,"'ANLN'",42,38,35,38.3333333333333,null,"H00626///Focal segmental glomerulosclerosis",null,null,"GO:0099738///cell cortex region+++GO:0030496///midbody+++GO:0005654///nucleoplasm+++GO:0005826///actomyosin contractile ring+++GO:0005938///cell cortex+++GO:0032059///bleb+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0042995///cell projection","GO:0017049///GTP-Rho binding+++GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0045296///cadherin binding","GO:0000281///mitotic cytokinesis+++GO:1904498///protein localization to mitotic actomyosin contractile ring+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:1904172///positive regulation of bleb assembly+++GO:0031106///septin ring organization+++GO:0051301///cell division+++GO:0000915///actomyosin contractile ring assembly+++GO:0090521///glomerular visceral epithelial cell migration+++GO:0000921///septin ring assembly+++GO:0030865///cortical cytoskeleton organization+++GO:0007096///regulation of exit from mitosis+++GO:0007049///cell cycle","anillin actin binding protein","[ANLN_HUMAN|Reviewed]RecName: Full=Anillin;+++[A0A024RA49_HUMAN|Unreviewed]SubName: Full=Anillin, actin binding protein (Scraps homolog, Drosophila), isoform CRA_e {ECO:0000313|EMBL:EAW94072.1};+++[A8K5D9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77424, highly similar to Homo sapiens anillin, actin binding protein (scraps homolog, Drosophila), mRNA {ECO:0000313|EMBL:BAF83943.1};+++[C9J0G4_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000406584}; Flags: Fragment;+++[C9JJT6_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000404979}; Flags: Fragment;+++[H7C0Y6_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000397465}; Flags: Fragment;+++[H7C167_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000398712}; Flags: Fragment;+++[H7C1C2_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000399553}; Flags: Fragment;+++[H7C1K5_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000400777}; Flags: Fragment;+++[H7C3R2_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000413441}; Flags: Fragment;+++[H7C3S1_HUMAN|Unreviewed]SubName: Full=Anillin {ECO:0000313|Ensembl:ENSP00000413522}; Flags: Fragment;"]
[54466,"'SPIN2A'",8.18,12.23,5.48,8.63,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005575///cellular_component","GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0035064///methylated histone binding","GO:0051726///regulation of cell cycle+++GO:0007049///cell cycle+++GO:0007276///gamete generation","spindlin family member 2A","[SPI2A_HUMAN|Reviewed]RecName: Full=Spindlin-2A; AltName: Full=Protein DXF34; AltName: Full=Spindlin-like protein 2A; Short=SPIN-2; Short=SPIN-2A;+++[A0A024R9W1_HUMAN|Unreviewed]SubName: Full=Spindlin family, member 2, isoform CRA_a {ECO:0000313|EMBL:EAW93243.1};+++[A0A087X074_HUMAN|Unreviewed]SubName: Full=Spindlin-2A {ECO:0000313|Ensembl:ENSP00000483149};"]
[54482,"'TRMT13'",108,120,100,109.333333333333,{"$nulls":4},"GO:0031430///M band","GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0008168///methyltransferase activity+++GO:0106050///tRNA 2'-O-methyltransferase activity+++GO:0008175///tRNA methyltransferase activity","GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0008033///tRNA processing","tRNA methyltransferase 13 homolog","[TRM13_HUMAN|Reviewed]RecName: Full=tRNA:m(4)X modification enzyme TRM13 homolog; EC=2.1.1.225; AltName: Full=Coiled-coil domain-containing protein 76;+++[Q5VVK9_HUMAN|Unreviewed]SubName: Full=tRNA:m(4)X modification enzyme TRM13 homolog {ECO:0000313|Ensembl:ENSP00000359158};+++[Q5VVL2_HUMAN|Unreviewed]SubName: Full=tRNA:m(4)X modification enzyme TRM13 homolog {ECO:0000313|Ensembl:ENSP00000359162};"]
[54494,"'C11orf71'",89,85,76,83.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003727///single-stranded RNA binding+++GO:0003723///RNA binding","GO:0051321///meiotic cell cycle+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","chromosome 11 open reading frame 71","[CK071_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf71;+++[A0A0A8K8C2_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 71 {ECO:0000313|EMBL:EAW67245.1}; SubName: Full=Up-regulated in lung cancer 7 {ECO:0000313|EMBL:BAQ19753.1};"]
[54534,"'MRPL50'",124,86,108,106,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0005840///ribosome+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit",null,"GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination","mitochondrial ribosomal protein L50","[RM50_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L50, mitochondrial; Short=L50mt; Short=MRP-L50; AltName: Full=Mitochondrial large ribosomal subunit protein mL50 {ECO:0000303|PubMed:25278503};"]
[54537,"'SHLD2'",268,257,217,247.333333333333,"04137///Mitophagy - animal+++04217///Necroptosis+++01200///Carbon metabolism+++00250///Alanine, aspartate and glutamate metabolism+++04964///Proximal tubule bicarbonate reclamation+++00910///Nitrogen metabolism+++01100///Metabolic pathways+++00220///Arginine biosynthesis+++04140///Autophagy - animal+++00471///D-Glutamine and D-glutamate metabolism","H01400///Secondary hyperammonemia+++H01267///Familial hyperinsulinemic hypoglycemia (HHF)","M00740///Methylaspartate cycle","R00243///L-glutamate:NAD+ oxidoreductase (deaminating) L-Glutamate + NAD+ + H2O <=> 2-Oxoglutarate + Ammonia + NADH + H++++R00248///L-Glutamate:NADP+ oxidoreductase (deaminating) L-Glutamate + NADP+ + H2O <=> 2-Oxoglutarate + Ammonia + NADPH + H+","GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0035861///site of double-strand break","GO:0005515///protein binding","GO:0006281///DNA repair+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining+++GO:0045830///positive regulation of isotype switching+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:0006974///cellular response to DNA damage stimulus","shieldin complex subunit 2","[SHLD2_HUMAN|Reviewed]RecName: Full=Shieldin complex subunit 2 {ECO:0000312|HGNC:HGNC:28773}; AltName: Full=Protein FAM35A {ECO:0000305}; AltName: Full=RINN1-REV7-interacting novel NHEJ regulator 2 {ECO:0000303|PubMed:29656893}; AltName: Full=Shield complex subunit 2;+++[A0A024R6H6_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 35, member A, isoform CRA_a {ECO:0000313|EMBL:EAW81364.1};+++[U3KQ89_HUMAN|Unreviewed]SubName: Full=Shieldin complex subunit 2 {ECO:0000313|Ensembl:ENSP00000475647}; Flags: Fragment;"]
[54554,"'WDR5B'",94,96,109,99.6666666666667,"04934///Cushing's syndrome",{"$nulls":3},"GO:0036064///ciliary basal body",null,"GO:0060271///cilium assembly","WD repeat domain 5B","[WDR5B_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 5B;"]
[5460,"'POU5F1'",0.98,3.9,4.77,3.21666666666667,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm","GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0035198///miRNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019955///cytokine binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003723///RNA binding+++GO:0044212///transcription regulatory region DNA binding","GO:0060965///negative regulation of gene silencing by miRNA+++GO:0001714///endodermal cell fate specification+++GO:0009786///regulation of asymmetric cell division+++GO:0009653///anatomical structure morphogenesis+++GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0003130///BMP signaling pathway involved in heart induction+++GO:0090308///regulation of methylation-dependent chromatin silencing+++GO:0090081///regulation of heart induction by regulation of canonical Wnt signaling pathway+++GO:0007275///multicellular organism development+++GO:0060795///cell fate commitment involved in formation of primary germ layer+++GO:0035019///somatic stem cell population maintenance+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0009611///response to wounding+++GO:0060913///cardiac cell fate determination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0001824///blastocyst development+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0010629///negative regulation of gene expression+++GO:0010628///positive regulation of gene expression","POU class 5 homeobox 1","[PO5F1_HUMAN|Reviewed]RecName: Full=POU domain, class 5, transcription factor 1; AltName: Full=Octamer-binding protein 3; Short=Oct-3; AltName: Full=Octamer-binding protein 4; Short=Oct-4; AltName: Full=Octamer-binding transcription factor 3; Short=OTF-3;+++[A0A0K0KMI2_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 transcript variant OCT4B4 {ECO:0000313|EMBL:AIK29477.1}; Flags: Fragment;+++[A0A0K0KMS3_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 transcript variant OCT4B6 {ECO:0000313|EMBL:AIK29479.1}; Flags: Fragment;+++[A0A0K0KMW9_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 transcript variant OCT4B5 {ECO:0000313|EMBL:AIK29478.1}; Flags: Fragment;+++[A0A1W2PP83_HUMAN|Unreviewed]SubName: Full=POU domain, class 5, transcription factor 1 {ECO:0000313|Ensembl:ENSP00000491205};+++[A7WPL9_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99189.1}; Flags: Fragment;+++[A7WPM0_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99190.1}; Flags: Fragment;+++[A7WPM1_HUMAN|Unreviewed]SubName: Full=Putative truncated POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99191.1};+++[A7WPM2_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99192.1}; Flags: Fragment;+++[A7WPM3_HUMAN|Unreviewed]SubName: Full=Putative truncated POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99193.1};+++[A7WPM4_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99194.1}; Flags: Fragment;+++[A7WPM5_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99195.1}; Flags: Fragment;+++[A7WPM6_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99196.1}; Flags: Fragment;+++[A7WPM7_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99197.1}; Flags: Fragment;+++[A7WPM8_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99198.1}; Flags: Fragment;+++[A7WPM9_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99199.1}; Flags: Fragment;+++[A7WPN0_HUMAN|Unreviewed]SubName: Full=POU domain class 5 transcription factor 1 {ECO:0000313|EMBL:CAO99200.1}; Flags: Fragment;+++[B5B8N7_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76268.1}; Flags: Fragment;+++[B5B8N8_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76269.1}; Flags: Fragment;+++[B5B8N9_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76270.1}; Flags: Fragment;+++[B5B8P0_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76271.1}; Flags: Fragment;+++[B5B8P1_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76272.1}; Flags: Fragment;+++[B5B8P2_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76273.1}; Flags: Fragment;+++[B5B8P3_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76274.1}; Flags: Fragment;+++[B5B8P4_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76275.1}; Flags: Fragment;+++[B5B8P5_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76276.1}; Flags: Fragment;+++[B5B8P6_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76277.1}; Flags: Fragment;+++[B5B8P7_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76278.1}; Flags: Fragment;+++[B5B8P8_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76279.1}; Flags: Fragment;+++[B5B8P9_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76280.1}; Flags: Fragment;+++[B5B8Q0_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76281.1}; Flags: Fragment;+++[B5B8Q1_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76282.1}; Flags: Fragment;+++[B5B8Q2_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76283.1}; Flags: Fragment;+++[B5B8Q3_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76284.1}; Flags: Fragment;+++[B5B8Q4_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 {ECO:0000313|EMBL:CAQ76285.1}; Flags: Fragment;+++[C3RUE0_HUMAN|Unreviewed]SubName: Full=POU domain transcription factor Oct4 isoform 3 {ECO:0000313|EMBL:ACD14148.1};+++[D2IYK3_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9Q3_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9Q6_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9Q7_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9Q9_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9R1_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9R2_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9R3_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9R4_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9R5_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9R7_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9R8_HUMAN|Unreviewed]SubName: Full=POU domain transcription factor OCT4 {ECO:0000313|EMBL:ADE48555.1};+++[D5K9R9_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[D5K9S1_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[E9LR73_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[E9LR75_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[E9LR77_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[E9LR79_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[F2Z381_HUMAN|Unreviewed]SubName: Full=POU class 5 homeobox 1 transcript variant 6 {ECO:0000313|EMBL:AID57229.1}; SubName: Full=POU class 5 homeobox 1 transcript variant OCT4B1 {ECO:0000313|EMBL:AID57228.1}; SubName: Full=POU class 5 homeobox 1 transcript variant OCT4B2 {ECO:0000313|EMBL:AIK29476.1}; SubName: Full=POU class 5 homeobox 1 transcript variant OCT4B3 {ECO:0000313|EMBL:AIK29475.1}; SubName: Full=POU domain, class 5, transcription factor 1 {ECO:0000313|Ensembl:ENSP00000425479};+++[M1S623_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[U3KQH6_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};"]
[54658,"'UGT1A1'",1,0,0,0.333333333333333,"01110///Biosynthesis of secondary metabolites+++00830///Retinol metabolism+++00982///Drug metabolism - cytochrome P450+++05204///Chemical carcinogenesis+++00860///Porphyrin and chlorophyll metabolism+++00983///Drug metabolism - other enzymes+++01100///Metabolic pathways+++00053///Ascorbate and aldarate metabolism+++00040///Pentose and glucuronate interconversions+++00980///Metabolism of xenobiotics by cytochrome P450+++00140///Steroid hormone biosynthesis","H01593///Osteoporosis+++H02055///Gilbert syndrome+++H02152///Transient familial neonatal hyperbilirubinemia+++H00208///Hyperbilirubinemia+++H02054///Crigler-Najjar syndrome","M00014///Glucuronate pathway (uronate pathway)+++M00129///Ascorbate biosynthesis, animals, glucose-1P => ascorbate","R04352///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Etiocholanolone + UDP-glucuronate <=> Etiocholan-3alpha-ol-17-one 3-glucuronide + UDP+++R08263///Morphine + UDP-glucuronate <=> Morphine-6-glucuronide + UDP+++R07106///UDP-glucuronate beta-D-glucuronosyltransferase   Trichloroethanol + UDP-glucuronate <=> Trichloroethanol glucuronide + UDP+++R02358///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Estrone + UDP-glucuronate <=> Estrone glucuronide + UDP+++R08261///UDP-glucuronate + Codeine <=> UDP + Codeine-6-glucuronide+++R02502///17beta-hydroxysteroid UDP-glucuronosyltransferase   Testosterone + UDP-glucuronate <=> Testosterone glucuronide + UDP+++R03091///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Estradiol-17beta + UDP-glucuronate <=> Estradiol-17beta 3-glucuronide + UDP+++R08615///UDP-glucuronate glucuronohydrolase   UDP-glucuronate + H2O <=> UDP + D-Glucuronate+++R02478///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Androsterone + UDP-glucuronate <=> Androsterone glucuronide + UDP+++R02902///Retinoate + UDP-glucuronate <=> all-trans-Retinoyl-beta-glucuronide + UDP+++R09426///4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide + UDP+++R01383///UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)   UDP-glucuronate + ROH <=> UDP + beta-D-Glucuronoside+++R04353///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   2-Methoxyestrone + UDP-glucuronate <=> 2-Methoxyestrone 3-glucuronide + UDP+++R09428///UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)   UDP-glucuronate + Acceptor <=> UDP + Acceptor beta-D-glucuronoside+++R04354///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   2-Methoxy-17beta-estradiol + UDP-glucuronate <=> 2-Methoxy-estradiol-17beta 3-glucuronide + UDP+++R02389///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   2 UDP-glucuronate + Bilirubin <=> 2 UDP + Bilirubin beta-diglucuronide+++R08262///Morphine + UDP-glucuronate <=> Morphine-3-glucuronide + UDP+++R08259///SN-38 + UDP-glucuronate <=> SN38 glucuronide + UDP+++R04683///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   UDP-glucuronate + Estriol <=> UDP + 16-Glucuronide-estriol+++R09427///4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> NNAL-N-glucuronide + UDP","GO:0005789///endoplasmic reticulum membrane+++GO:0070069///cytochrome complex+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005783///endoplasmic reticulum","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0001972///retinoic acid binding+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0004857///enzyme inhibitor activity+++GO:0008194///UDP-glycosyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0005496///steroid binding+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0046982///protein heterodimerization activity+++GO:0016740///transferase activity","GO:0052696///flavonoid glucuronidation+++GO:0071392///cellular response to estradiol stimulus+++GO:0008210///estrogen metabolic process+++GO:0052697///xenobiotic glucuronidation+++GO:0031100///animal organ regeneration+++GO:0043086///negative regulation of catalytic activity+++GO:0010033///response to organic substance+++GO:1904224///negative regulation of glucuronosyltransferase activity+++GO:0017144///drug metabolic process+++GO:0014070///response to organic cyclic compound+++GO:0042573///retinoic acid metabolic process+++GO:0006789///bilirubin conjugation+++GO:0045939///negative regulation of steroid metabolic process+++GO:0070980///biphenyl catabolic process+++GO:0007584///response to nutrient+++GO:0051384///response to glucocorticoid+++GO:2001030///negative regulation of cellular glucuronidation+++GO:0042594///response to starvation+++GO:0045471///response to ethanol+++GO:0046483///heterocycle metabolic process+++GO:0042493///response to drug+++GO:0042167///heme catabolic process+++GO:0045922///negative regulation of fatty acid metabolic process+++GO:0071466///cellular response to xenobiotic stimulus+++GO:0071361///cellular response to ethanol+++GO:0032870///cellular response to hormone stimulus+++GO:0052695///cellular glucuronidation+++GO:0008202///steroid metabolic process+++GO:0006953///acute-phase response+++GO:0001889///liver development+++GO:0032496///response to lipopolysaccharide+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0048545///response to steroid hormone+++GO:0051552///flavone metabolic process","UDP glucuronosyltransferase family 1 member A1","[UD11_HUMAN|Reviewed]RecName: Full=UDP-glucuronosyltransferase 1-1; Short=UDPGT 1-1; Short=UGT1*1; Short=UGT1-01; Short=UGT1.1; EC=2.4.1.17; AltName: Full=Bilirubin-specific UDPGT isozyme 1; Short=hUG-BR1; AltName: Full=UDP-glucuronosyltransferase 1-A; Short=UGT-1A; Short=UGT1A; AltName: Full=UDP-glucuronosyltransferase 1A1; Flags: Precursor;+++[A0A0M4UT75_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltranserase {ECO:0000313|EMBL:BAS31009.1};+++[A0A1L2FNL9_HUMAN|Unreviewed]SubName: Full=UDP glucuronosyltransferase 1 family polypeptide A1 {ECO:0000313|EMBL:ANZ22923.1}; EC=2.4.1.17 {ECO:0000313|EMBL:ANZ22923.1}; Flags: Fragment;+++[B6EBF5_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase 1 A1 {ECO:0000313|EMBL:ACI45243.1}; Flags: Fragment;+++[I6U9T8_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6UJG0_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6V2C0_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6VBT8_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6VBU3_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6VBU7_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6VE22_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6VE27_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[I6VE32_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[Q5DT03_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[Q9BX76_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucronosyltrasferase 1-1 {ECO:0000313|EMBL:AAK31204.1}; Flags: Fragment;+++[Q9H3F9_HUMAN|Unreviewed]SubName: Full=UDP-glucuronosyltransferase {ECO:0000313|EMBL:AAG43197.1}; Flags: Fragment;+++[W6JGU4_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase {ECO:0000313|EMBL:BAO48178.1}; Flags: Fragment;+++[W6JGU6_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase {ECO:0000313|EMBL:BAO48183.1}; Flags: Fragment;+++[W6JGV5_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronoslytransferase {ECO:0000313|EMBL:BAO48179.1};+++[W6JGV8_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase {ECO:0000313|EMBL:BAO48184.1}; Flags: Fragment;+++[W6JHY2_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase {ECO:0000313|EMBL:BAO48181.1}; Flags: Fragment;+++[W6JIA6_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase {ECO:0000313|EMBL:BAO48177.1}; Flags: Fragment;+++[W6JIB0_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase {ECO:0000313|EMBL:BAO48182.1}; Flags: Fragment;+++[W6JNV6_HUMAN|Unreviewed]SubName: Full=Bilirubin UDP-glucuronosyltransferase {ECO:0000313|EMBL:BAO48180.1}; Flags: Fragment;"]
[5470,"'PPEF2'",0,3,0,1,"04745///Phototransduction - fly",{"$nulls":3},"GO:0001750///photoreceptor outer segment+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0001917///photoreceptor inner segment","GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0030544///Hsp70 protein binding+++GO:0016787///hydrolase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0051879///Hsp90 protein binding+++GO:0030145///manganese ion binding+++GO:0005506///iron ion binding","GO:0043405///regulation of MAP kinase activity+++GO:0006470///protein dephosphorylation+++GO:0007601///visual perception+++GO:0050896///response to stimulus+++GO:0043409///negative regulation of MAPK cascade+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0043506///regulation of JUN kinase activity+++GO:0050906///detection of stimulus involved in sensory perception","protein phosphatase with EF-hand domain 2","[PPE2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase with EF-hands 2; Short=PPEF-2; EC=3.1.3.16;+++[E7EPQ9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase with EF-hands 2 {ECO:0000313|Ensembl:ENSP00000426186};+++[Q14DF6_HUMAN|Unreviewed]SubName: Full=PPEF2 protein {ECO:0000313|EMBL:AAI13380.1};"]
[54741,"'LEPROT'",1843.72,1743.01,1916.86,1834.53,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0043235///receptor complex+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0016021///integral component of membrane+++GO:0009897///external side of plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0005768///endosome","GO:0042802///identical protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0019955///cytokine binding+++GO:0017046///peptide hormone binding+++GO:0038021///leptin receptor activity+++GO:0005102///signaling receptor binding","GO:0001525///angiogenesis+++GO:0019953///sexual reproduction+++GO:0045721///negative regulation of gluconeogenesis+++GO:0044321///response to leptin+++GO:0019221///cytokine-mediated signaling pathway+++GO:0008203///cholesterol metabolic process+++GO:0042593///glucose homeostasis+++GO:0006909///phagocytosis+++GO:0046850///regulation of bone remodeling+++GO:0033210///leptin-mediated signaling pathway+++GO:0030217///T cell differentiation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0006112///energy reserve metabolic process+++GO:0010507///negative regulation of autophagy+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0060259///regulation of feeding behavior+++GO:0007166///cell surface receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0097009///energy homeostasis+++GO:0051346///negative regulation of hydrolase activity+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0032511///late endosome to vacuole transport via multivesicular body sorting pathway+++GO:0098868///bone growth+++GO:0060400///negative regulation of growth hormone receptor signaling pathway+++GO:2000009///negative regulation of protein localization to cell surface","leptin receptor overlapping transcript","[OBRG_HUMAN|Reviewed]RecName: Full=Leptin receptor gene-related protein; AltName: Full=Endospanin-1; AltName: Full=Leptin receptor overlapping transcript protein; AltName: Full=OB-R gene-related protein; Short=OB-RGRP;+++[A0A087X0N2_HUMAN|Unreviewed]SubName: Full=Leptin receptor gene-related protein {ECO:0000313|Ensembl:ENSP00000483521};+++[A0A0U3T571_HUMAN|Unreviewed]SubName: Full=Leptin receptor {ECO:0000313|EMBL:ALV89813.1}; Flags: Fragment;+++[A0A2Z6I6G4_HUMAN|Unreviewed]SubName: Full=LEPR protein ( OBR,CD295protein ) {ECO:0000313|EMBL:BBF17090.1}; Flags: Fragment;+++[A0A2Z6IBQ7_HUMAN|Unreviewed]SubName: Full=LEPR protein {ECO:0000313|EMBL:BBF17159.1}; Flags: Fragment;+++[A2RRQ4_HUMAN|Unreviewed]SubName: Full=LEPR protein {ECO:0000313|EMBL:AAI31780.1};"]
[54765,"'TRIM44'",1432,1248,1239,1306.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00635///Aniridia",null,null,"GO:0005882///intermediate filament+++GO:0070062///extracellular exosome+++GO:0034451///centriolar satellite+++GO:0005913///cell-cell adherens junction+++GO:0005815///microtubule organizing center+++GO:0045095///keratin filament+++GO:0071944///cell periphery+++GO:0005730///nucleolus+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0010468///regulation of gene expression+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0050821///protein stabilization+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0061944///negative regulation of protein K48-linked ubiquitination+++GO:0002230///positive regulation of defense response to virus by host+++GO:0045893///positive regulation of transcription, DNA-templated","tripartite motif containing 44","[TRI44_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 44; AltName: Full=Protein DIPB;"]
[54798,"'DCHS2'",0,4,3,2.33333333333333,"04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species","H01393///Van Maldergem syndrome (VMLDS/VMS)+++H01868///Mitral valve prolapse",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005509///calcium ion binding","GO:0008150///biological_process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","dachsous cadherin-related 2","[PCD23_HUMAN|Reviewed]RecName: Full=Protocadherin-23; AltName: Full=Cadherin-27; AltName: Full=Cadherin-like protein CDHJ; AltName: Full=Cadherin-like protein VR8; AltName: Full=Protein dachsous homolog 2; AltName: Full=Protocadherin PCDHJ;+++[A0A096LNH0_HUMAN|Unreviewed]SubName: Full=Protocadherin-23 {ECO:0000313|Ensembl:ENSP00000349768};+++[A0A0A0MRC0_HUMAN|Unreviewed]SubName: Full=Protocadherin-23 {ECO:0000313|Ensembl:ENSP00000345062};+++[D3DP12_HUMAN|Unreviewed]SubName: Full=Dachsous 2 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAX04945.1};+++[Q6V1P8_HUMAN|Unreviewed]SubName: Full=Protocadherin protein {ECO:0000313|EMBL:AAR10444.1}; Flags: Fragment;"]
[54812,"'AFTPH'",304,263,292,286.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0030121///AP-1 adaptor complex+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus","GO:0030276///clathrin binding","GO:0046907///intracellular transport+++GO:0015031///protein transport","aftiphilin","[AFTIN_HUMAN|Reviewed]RecName: Full=Aftiphilin;+++[A0A0A0MSN6_HUMAN|Unreviewed]SubName: Full=Aftiphilin {ECO:0000313|Ensembl:ENSP00000397726};+++[A0A0U1RR74_HUMAN|Unreviewed]SubName: Full=Aftiphilin {ECO:0000313|Ensembl:ENSP00000489378}; Flags: Fragment;+++[B8ZZI9_HUMAN|Unreviewed]SubName: Full=Aftiphilin {ECO:0000313|Ensembl:ENSP00000386913}; Flags: Fragment;+++[Q3LIF3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla10388 {ECO:0000313|EMBL:BAE45715.1}; Flags: Fragment;+++[Q53GW0_HUMAN|Unreviewed]SubName: Full=Aftiphilin protein isoform b variant {ECO:0000313|EMBL:BAD96541.1}; Flags: Fragment;"]
[54839,"'LRRC49'",76,99,91,88.6666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005856///cytoskeleton",null,"GO:0036158///outer dynein arm assembly","leucine rich repeat containing 49","[LRC49_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 49; AltName: Full=Tubulin polyglutamylase complex subunit 4; Short=PGs4;+++[A0A0B4J283_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000453728};+++[B7Z7G0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53676, highly similar to Leucine-rich repeat-containing protein 49 {ECO:0000313|EMBL:BAH13596.1};+++[H0YKE9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000452775};+++[H0YKI5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000452821}; Flags: Fragment;+++[H0YKQ0_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000452894}; Flags: Fragment;+++[H0YKS7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000452925}; Flags: Fragment;+++[H0YLQ8_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000453300}; Flags: Fragment;+++[H0YLZ6_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000453402}; Flags: Fragment;+++[H0YM43_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000453456};+++[H0YMT2_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000453731};+++[H0YMZ6_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000453807};+++[H0YNI5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000454026}; Flags: Fragment;+++[H0YNV5_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat containing 49, isoform CRA_b {ECO:0000313|EMBL:EAW77865.1}; SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000454170};+++[H3BNA9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 49 {ECO:0000313|Ensembl:ENSP00000454760}; Flags: Fragment;"]
[54854,"'FAM83E'",0,4,0,1.33333333333333,"01100///Metabolic pathways+++04666///Fc gamma R-mediated phagocytosis+++03010///Ribosome+++00600///Sphingolipid metabolism+++05152///Tuberculosis+++04071///Sphingolipid signaling pathway+++04072///Phospholipase D signaling pathway+++04371///Apelin signaling pathway+++04020///Calcium signaling pathway+++04370///VEGF signaling pathway",null,"M00177///Ribosome, eukaryotes+++M00179///Ribosome, archaea+++M00100///Sphingosine degradation","R02976///ATP:sphinganine 1-phosphotransferase ATP + Sphinganine <=> ADP + Sphinganine 1-phosphate+++R01926///ATP:sphingosine 1-phosphotransferase; sphingosine Sphingosine + ATP <=> Sphingosine 1-phosphate + ADP",null,"GO:0019901///protein kinase binding",null,"family with sequence similarity 83 member E","[FA83E_HUMAN|Reviewed]RecName: Full=Protein FAM83E {ECO:0000305};+++[M0QZ37_HUMAN|Unreviewed]SubName: Full=Protein FAM83E {ECO:0000313|Ensembl:ENSP00000470271}; Flags: Fragment;"]
[54869,"'EPS8L1'",129,122,95,115.333333333333,"04270///Vascular smooth muscle contraction+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++05205///Proteoglycans in cancer+++04510///Focal adhesion",{"$nulls":3},"GO:0032587///ruffle membrane+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005930///axoneme+++GO:0005929///cilium+++GO:0005829///cytosol+++GO:0031514///motile cilium+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome+++GO:0042995///cell projection","GO:0045296///cadherin binding+++GO:0003779///actin binding+++GO:0016301///kinase activity+++GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0042608///T cell receptor binding","GO:0035023///regulation of Rho protein signal transduction+++GO:0016310///phosphorylation+++GO:0007266///Rho protein signal transduction+++GO:1900029///positive regulation of ruffle assembly","EPS8 like 1","[ES8L1_HUMAN|Reviewed]RecName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 1; Short=EPS8-like protein 1; AltName: Full=Epidermal growth factor receptor pathway substrate 8-related protein 1; Short=EPS8-related protein 1;+++[B4DKV7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60287, highly similar to Epidermal growth factor receptor kinase substrate 8-like protein 1 {ECO:0000313|EMBL:BAG59319.1};+++[K7EKX9_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 1 {ECO:0000313|Ensembl:ENSP00000465830};+++[K7ELW3_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 1 {ECO:0000313|Ensembl:ENSP00000466245};+++[K7EN83_HUMAN|Unreviewed]SubName: Full=EPS8-like 1, isoform CRA_d {ECO:0000313|EMBL:EAW72331.1}; SubName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 1 {ECO:0000313|Ensembl:ENSP00000466828};"]
[54892,"'NCAPG2'",88,89,60,79,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0000796///condensin complex+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0035064///methylated histone binding+++GO:0098772///molecular function regulator+++GO:0043425///bHLH transcription factor binding+++GO:0046872///metal ion binding","GO:0030261///chromosome condensation+++GO:0007049///cell cycle+++GO:0006366///transcription by RNA polymerase II+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0051301///cell division+++GO:0030218///erythrocyte differentiation+++GO:0001833///inner cell mass cell proliferation+++GO:2000273///positive regulation of signaling receptor activity+++GO:0045647///negative regulation of erythrocyte differentiation","non-SMC condensin II complex subunit G2","[CNDG2_HUMAN|Reviewed]RecName: Full=Condensin-2 complex subunit G2; AltName: Full=Chromosome-associated protein G2; Short=CAP-G2; Short=hCAP-G2; AltName: Full=Leucine zipper protein 5; AltName: Full=Non-SMC condensin II complex subunit G2;+++[B3KRQ2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34689 fis, clone MESAN2000815, highly similar to Homo sapiens leucine zipper protein 5 (LUZP5), mRNA {ECO:0000313|EMBL:BAG52464.1};+++[F8WE06_HUMAN|Unreviewed]SubName: Full=Condensin-2 complex subunit G2 {ECO:0000313|Ensembl:ENSP00000414337};+++[H0Y6U5_HUMAN|Unreviewed]SubName: Full=Condensin-2 complex subunit G2 {ECO:0000313|Ensembl:ENSP00000408080}; Flags: Fragment;+++[Q86YX6_HUMAN|Unreviewed]RecName: Full=Metallothionein {ECO:0000256|RuleBase:RU000621};"]
[54903,"'MKS1'",151,140,138,143,null,"H00530///Joubert syndrome+++H00418///Bardet-Biedl syndrome (BBS)+++H00261///Meckel syndrome (MKS)",null,null,"GO:0016020///membrane+++GO:0035869///ciliary transition zone+++GO:0005814///centriole+++GO:0036064///ciliary basal body+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0036038///MKS complex+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0048706///embryonic skeletal system development+++GO:1990403///embryonic brain development+++GO:2000095///regulation of Wnt signaling pathway, planar cell polarity pathway+++GO:0010669///epithelial structure maintenance+++GO:0008589///regulation of smoothened signaling pathway+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0060322///head development+++GO:0001843///neural tube closure+++GO:0061009///common bile duct development+++GO:0060411///cardiac septum morphogenesis+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0044458///motile cilium assembly+++GO:0007224///smoothened signaling pathway+++GO:0003279///cardiac septum development+++GO:1901620///regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0060271///cilium assembly+++GO:0007368///determination of left/right symmetry+++GO:0003271///smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation+++GO:0030030///cell projection organization+++GO:1905515///non-motile cilium assembly+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0042733///embryonic digit morphogenesis","Meckel syndrome, type 1","[MKS1_HUMAN|Reviewed]RecName: Full=Meckel syndrome type 1 protein;+++[A0A0S2Z5J0_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 isoform 2 {ECO:0000313|EMBL:ALQ34120.1};+++[A0A0S2Z5L9_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 isoform 1 {ECO:0000313|EMBL:ALQ34119.1}; Flags: Fragment;+++[A0A0S2Z5Z2_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 isoform 3 {ECO:0000313|EMBL:ALQ34121.1};+++[B4DVC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53497, highly similar to Meckel syndrome type 1 protein {ECO:0000313|EMBL:BAG62637.1};+++[H0Y2S2_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000316631};+++[J3KRR3_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000462129};+++[J3KRV5_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000462179}; Flags: Fragment;+++[J3KSB7_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000462411};+++[J3KSC6_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000462423};+++[J3KSF4_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000462460}; Flags: Fragment;+++[J3QQP4_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000463826}; Flags: Fragment;+++[J9PBQ5_HUMAN|Unreviewed]SubName: Full=Meckel syndrome type 1 protein {ECO:0000313|Ensembl:ENSP00000376828};"]
[54930,"'HAUS4'",131,193,155,159.666666666667,{"$nulls":4},"GO:0005819///spindle+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0070652///HAUS complex+++GO:0005813///centrosome+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0000086///G2/M transition of mitotic cell cycle","HAUS augmin like complex subunit 4","[HAUS4_HUMAN|Reviewed]RecName: Full=HAUS augmin-like complex subunit 4;+++[G3V2I5_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450680}; Flags: Fragment;+++[G3V4X7_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452058}; Flags: Fragment;+++[G3V541_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452165}; Flags: Fragment;+++[G3V5A5_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452261}; Flags: Fragment;+++[G3V5Z2_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452595}; Flags: Fragment;+++[H0YIZ6_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450542}; Flags: Fragment;+++[H0YJ09_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450612}; Flags: Fragment;"]
[54939,"'COMMD4'",327,347,300,324.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","COMM domain containing 4","[COMD4_HUMAN|Reviewed]RecName: Full=COMM domain-containing protein 4;+++[A0A0B4J287_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000455249};+++[H3BM91_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000454283}; Flags: Fragment;+++[H3BPG2_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000455303}; Flags: Fragment;+++[H3BQF2_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000455750};+++[H3BRX0_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000456440};+++[H3BTV9_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000457348};"]
[54956,"'PARP16'",159.06,160,181.02,166.693333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0005515///protein binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019900///kinase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0016740///transferase activity","GO:0060548///negative regulation of cell death+++GO:0006471///protein ADP-ribosylation+++GO:0006986///response to unfolded protein+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034356///NAD biosynthesis via nicotinamide riboside salvage pathway+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0070213///protein auto-ADP-ribosylation","poly(ADP-ribose) polymerase family member 16","[PAR16_HUMAN|Reviewed]RecName: Full=Mono [ADP-ribose] polymerase PARP16 {ECO:0000305}; EC=2.4.2.30 {ECO:0000269|PubMed:22701565}; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 15 {ECO:0000303|PubMed:20106667}; AltName: Full=Poly [ADP-ribose] polymerase 16; Short=PARP-16;+++[H3BV75_HUMAN|Unreviewed]SubName: Full=Mono [ADP-ribose] polymerase PARP16 {ECO:0000313|Ensembl:ENSP00000457982}; Flags: Fragment;"]
[54963,"'UCKL1'",583,681,591,618.333333333333,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00983///Drug metabolism - other enzymes",null,null,"R08232///ATP:5-fluorouridine 5'-phosphotransferase   5-Fluorouridine + ATP <=> 5-Fluorouridine monophosphate + ADP+++R02332///dUTP:uridine 5'-phosphotransferase   dUTP + Uridine <=> dUDP + UMP+++R02096///dTTP:cytidine 5'-phosphotransferase   dTTP + Cytidine <=> dTDP + CMP+++R02091///dGTP:cytidine 5'-phosphotransferase   dGTP + Cytidine <=> dGDP + CMP+++R00513///ATP:cytidine 5'-phosphotransferase   ATP + Cytidine <=> ADP + CMP+++R00516///UTP:cytidine 5'-phosphotransferase   UTP + Cytidine <=> UDP + CMP+++R02097///dTTP:uridine 5'-phosphotransferase   dTTP + Uridine <=> dTDP + UMP+++R00517///GTP:cytidine 5'-phosphotransferase   GTP + Cytidine <=> GDP + CMP+++R01880///dGTP:uridine 5'-phosphotransferase   dGTP + Uridine <=> dGDP + UMP+++R01548///dATP:cytidine 5'-phosphotransferase   dATP + Cytidine <=> dADP + CMP+++R00962///ITP:cytidine 5'-phosphotransferase   ITP + Cytidine <=> IDP + CMP+++R02327///dCTP:uridine 5'-phosphotransferase   dCTP + Uridine <=> dCDP + UMP+++R01549///dATP:uridine 5'-phosphotransferase   dATP + Uridine <=> dADP + UMP+++R02371///dCTP:cytidine 5'-phosphotransferase   dCTP + Cytidine <=> dCDP + CMP+++R00968///GTP:uridine 5'-phosphotransferase   GTP + Uridine <=> GDP + UMP+++R02372///dUTP:cytidine 5'-phosphotransferase   dUTP + Cytidine <=> dUDP + CMP+++R00967///UTP:uridine 5'-phosphotransferase   UTP + Uridine <=> UDP + UMP+++R00970///ITP:uridine 5'-phosphotransferase   ITP + Uridine <=> IDP + UMP+++R00964///ATP:uridine 5'-phosphotransferase   ATP + Uridine <=> ADP + UMP","GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0004849///uridine kinase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity","GO:0044206///UMP salvage+++GO:0043097///pyrimidine nucleoside salvage+++GO:0016032///viral process+++GO:0016310///phosphorylation+++GO:0006222///UMP biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0044211///CTP salvage","uridine-cytidine kinase 1 like 1","[UCKL1_HUMAN|Reviewed]RecName: Full=Uridine-cytidine kinase-like 1; EC=2.7.1.48;+++[Q53HM1_HUMAN|Unreviewed]RecName: Full=Uridine-cytidine kinase {ECO:0000256|RuleBase:RU003825}; EC=2.7.1.48 {ECO:0000256|RuleBase:RU003825}; Flags: Fragment;+++[Q5JWV1_HUMAN|Unreviewed]SubName: Full=Uridine-cytidine kinase-like 1 {ECO:0000313|Ensembl:ENSP00000402994}; Flags: Fragment;"]
[5499,"'PPP1CA'",1661,1555,1586,1600.66666666667,"04022///cGMP-PKG signaling pathway+++04921///Oxytocin signaling pathway+++03015///mRNA surveillance pathway+++04510///Focal adhesion+++04611///Platelet activation+++05031///Amphetamine addiction+++04728///Dopaminergic synapse+++04720///Long-term potentiation+++04810///Regulation of actin cytoskeleton+++04931///Insulin resistance+++05168///Herpes simplex infection+++04218///Cellular senescence+++05034///Alcoholism+++04390///Hippo signaling pathway+++04114///Oocyte meiosis+++04261///Adrenergic signaling in cardiomyocytes+++04750///Inflammatory mediator regulation of TRP channels+++04113///Meiosis - yeast+++05205///Proteoglycans in cancer+++04910///Insulin signaling pathway+++04270///Vascular smooth muscle contraction+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005913///cell-cell adherens junction+++GO:0043204///perikaryon+++GO:0043197///dendritic spine+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0098793///presynapse+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0005654///nucleoplasm+++GO:0042587///glycogen granule+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0098794///postsynapse+++GO:0005886///plasma membrane+++GO:0043005///neuron projection+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0000164///protein phosphatase type 1 complex","GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0044877///protein-containing complex binding+++GO:0008157///protein phosphatase 1 binding+++GO:0005515///protein binding+++GO:0016791///phosphatase activity+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0046872///metal ion binding+++GO:0043021///ribonucleoprotein complex binding","GO:0007049///cell cycle+++GO:0030324///lung development+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:1904886///beta-catenin destruction complex disassembly+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0005977///glycogen metabolic process+++GO:0005981///regulation of glycogen catabolic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0032922///circadian regulation of gene expression+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0010288///response to lead ion+++GO:0006470///protein dephosphorylation+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005975///carbohydrate metabolic process+++GO:0042752///regulation of circadian rhythm+++GO:0036496///regulation of translational initiation by eIF2 alpha dephosphorylation+++GO:0098609///cell-cell adhesion+++GO:0051301///cell division+++GO:0016311///dephosphorylation","protein phosphatase 1 catalytic subunit alpha","[PP1A_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; Short=PP-1A; EC=3.1.3.16 {ECO:0000269|PubMed:26083323};+++[A0A140VJS9_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[C0STL0_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1, catalytic subunit, alpha isoform {ECO:0000313|EMBL:BAH56195.1}; Flags: Fragment;+++[C4TNW5_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1, catalytic subunit, alpha {ECO:0000313|EMBL:BAH69083.1}; Flags: Fragment;+++[C4TNW6_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1, catalytic subunit, alpha {ECO:0000313|EMBL:BAH69084.1}; Flags: Fragment;+++[E9PMD7_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[F5H037_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase PP1-alpha catalytic subunit {ECO:0000313|Ensembl:ENSP00000438409}; Flags: Fragment;+++[F5H1L6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase PP1-alpha catalytic subunit {ECO:0000313|Ensembl:ENSP00000439568}; Flags: Fragment;"]
[5500,"'PPP1CB'",1311,1131,1157,1199.66666666667,"04114///Oocyte meiosis+++04921///Oxytocin signaling pathway+++04931///Insulin resistance+++04750///Inflammatory mediator regulation of TRP channels+++04024///cAMP signaling pathway+++04022///cGMP-PKG signaling pathway+++05034///Alcoholism+++04270///Vascular smooth muscle contraction+++04910///Insulin signaling pathway+++04390///Hippo signaling pathway+++04113///Meiosis - yeast+++04728///Dopaminergic synapse+++04720///Long-term potentiation+++04261///Adrenergic signaling in cardiomyocytes+++04611///Platelet activation+++05031///Amphetamine addiction+++04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04218///Cellular senescence+++05168///Herpes simplex infection+++03015///mRNA surveillance pathway+++05205///Proteoglycans in cancer",{"$nulls":3},"GO:0072357///PTW/PP1 phosphatase complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000164///protein phosphatase type 1 complex","GO:0050115///myosin-light-chain-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0017018///myosin phosphatase activity+++GO:0016791///phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0046872///metal ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0032922///circadian regulation of gene expression+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0005975///carbohydrate metabolic process+++GO:0030155///regulation of cell adhesion+++GO:0042752///regulation of circadian rhythm+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0048511///rhythmic process+++GO:0005977///glycogen metabolic process+++GO:0006470///protein dephosphorylation","protein phosphatase 1 catalytic subunit beta","[PP1B_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Short=PP-1B; Short=PPP1CD; EC=3.1.3.16; EC=3.1.3.53;+++[C9J9S3_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[C9JP48_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[E7ETD8_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[F8WE71_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase PP1-beta catalytic subunit {ECO:0000313|Ensembl:ENSP00000394589};+++[H0Y3Y6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase PP1-beta catalytic subunit {ECO:0000313|Ensembl:ENSP00000388056}; Flags: Fragment;+++[V9HW04_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};"]
[55023,"'PHIP'",504,506,452,487.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0005634///nucleus+++GO:0005802///trans-Golgi network+++GO:0005765///lysosomal membrane+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0036064///ciliary basal body+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton","GO:0005158///insulin receptor binding+++GO:0070577///lysine-acetylated histone binding+++GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization+++GO:0099041///vesicle tethering to Golgi+++GO:0008286///insulin receptor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0060322///head development+++GO:0022604///regulation of cell morphogenesis+++GO:0008589///regulation of smoothened signaling pathway+++GO:0035264///multicellular organism growth+++GO:0008284///positive regulation of cell proliferation+++GO:0008360///regulation of cell shape+++GO:0001932///regulation of protein phosphorylation+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0060271///cilium assembly+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0007507///heart development+++GO:0045893///positive regulation of transcription, DNA-templated","pleckstrin homology domain interacting protein","[PHIP_HUMAN|Reviewed]RecName: Full=PH-interacting protein; Short=PHIP; AltName: Full=IRS-1 PH domain-binding protein; AltName: Full=WD repeat-containing protein 11;"]
[5504,"'PPP1R2'",482,452,460,464.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000164///protein phosphatase type 1 complex","GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding","GO:0005977///glycogen metabolic process+++GO:0009966///regulation of signal transduction+++GO:0006091///generation of precursor metabolites and energy+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0005975///carbohydrate metabolic process","protein phosphatase 1 regulatory inhibitor subunit 2","[IPP2_HUMAN|Reviewed]RecName: Full=Protein phosphatase inhibitor 2; Short=IPP-2;+++[E7EMN6_HUMAN|Unreviewed]SubName: Full=Protein phosphatase inhibitor 2 {ECO:0000313|Ensembl:ENSP00000400238}; Flags: Fragment;+++[E7EUI7_HUMAN|Unreviewed]SubName: Full=Protein phosphatase inhibitor 2 {ECO:0000313|Ensembl:ENSP00000406725};+++[H7C416_HUMAN|Unreviewed]SubName: Full=Protein phosphatase inhibitor 2 {ECO:0000313|Ensembl:ENSP00000415175}; Flags: Fragment;+++[Q6NXS2_HUMAN|Unreviewed]SubName: Full=PPP1R2 protein {ECO:0000313|EMBL:AAH66921.1};"]
[55062,"'WIPI1'",619,531,514,554.666666666667,"04138///Autophagy - yeast+++04140///Autophagy - animal+++04136///Autophagy - other",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0000407///phagophore assembly site+++GO:0005856///cytoskeleton+++GO:0000139///Golgi membrane+++GO:0000421///autophagosome membrane+++GO:0005794///Golgi apparatus+++GO:0019898///extrinsic component of membrane+++GO:0034045///phagophore assembly site membrane+++GO:0005768///endosome+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0030136///clathrin-coated vesicle+++GO:0005829///cytosol","GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0050681///androgen receptor binding+++GO:0005102///signaling receptor binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0005515///protein binding+++GO:0030331///estrogen receptor binding","GO:0006497///protein lipidation+++GO:0048203///vesicle targeting, trans-Golgi to endosome+++GO:0034497///protein localization to phagophore assembly site+++GO:0009267///cellular response to starvation+++GO:0016236///macroautophagy+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0000422///autophagy of mitochondrion+++GO:0000045///autophagosome assembly+++GO:0006914///autophagy","WD repeat domain, phosphoinositide interacting 1","[WIPI1_HUMAN|Reviewed]RecName: Full=WD repeat domain phosphoinositide-interacting protein 1; Short=WIPI-1; AltName: Full=Atg18 protein homolog; AltName: Full=WD40 repeat protein interacting with phosphoinositides of 49 kDa; Short=WIPI 49 kDa;+++[A0A024R8L5_HUMAN|Unreviewed]SubName: Full=WD repeat domain, phosphoinositide interacting 1, isoform CRA_b {ECO:0000313|EMBL:EAW89059.1};+++[B4DX63_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57645, highly similar to WD repeat domain phosphoinositide-interacting protein 1 {ECO:0000313|EMBL:BAG63275.1};+++[G5EA37_HUMAN|Unreviewed]SubName: Full=WD repeat domain phosphoinositide-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000437345}; SubName: Full=WD repeat domain, phosphoinositide interacting 1, isoform CRA_a {ECO:0000313|EMBL:EAW89057.1};+++[K7EK57_HUMAN|Unreviewed]SubName: Full=WD repeat domain phosphoinositide-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000465470};+++[K7EKC5_HUMAN|Unreviewed]SubName: Full=WD repeat domain phosphoinositide-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000465557}; Flags: Fragment;+++[K7EKN0_HUMAN|Unreviewed]SubName: Full=WD repeat domain phosphoinositide-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000465695}; Flags: Fragment;+++[K7ELY0_HUMAN|Unreviewed]SubName: Full=WD repeat domain phosphoinositide-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000466270}; Flags: Fragment;"]
[55084,"'SOBP'",276,325,292,297.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0032184///SUMO polymer binding","GO:0007605///sensory perception of sound+++GO:0007626///locomotory behavior+++GO:0090102///cochlea development+++GO:0042472///inner ear morphogenesis+++GO:0050890///cognition","sine oculis binding protein homolog","[SOBP_HUMAN|Reviewed]RecName: Full=Sine oculis-binding protein homolog; AltName: Full=Jackson circler protein 1;+++[A0A0C4DGT7_HUMAN|Unreviewed]SubName: Full=Sine oculis-binding protein homolog {ECO:0000313|Ensembl:ENSP00000478366};+++[Q24K27_HUMAN|Unreviewed]SubName: Full=SOBP protein {ECO:0000313|EMBL:AAI13967.1}; Flags: Fragment;"]
[55101,"'DMAC2'",625,657,711,664.333333333333,{"$nulls":4},"GO:0005747///mitochondrial respiratory chain complex I+++GO:0019005///SCF ubiquitin ligase complex+++GO:0005739///mitochondrion","GO:0004842///ubiquitin-protein transferase activity","GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0016567///protein ubiquitination","distal membrane arm assembly complex 2","[DMAC2_HUMAN|Reviewed]RecName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000305}; AltName: Full=ATP synthase subunit s-like protein {ECO:0000305};+++[A0A024R0K4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW57045.1};+++[B4DFT4_HUMAN|Unreviewed]SubName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000313|Ensembl:ENSP00000468059}; SubName: Full=cDNA FLJ59869 {ECO:0000313|EMBL:BAG57545.1};+++[K7EIV4_HUMAN|Unreviewed]SubName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000313|Ensembl:ENSP00000464907}; Flags: Fragment;+++[K7ESN5_HUMAN|Unreviewed]SubName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000313|Ensembl:ENSP00000468796}; Flags: Fragment;+++[M0QX81_HUMAN|Unreviewed]SubName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000313|Ensembl:ENSP00000468966};+++[M0QZC4_HUMAN|Unreviewed]SubName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000313|Ensembl:ENSP00000470444};+++[M0QZP7_HUMAN|Unreviewed]SubName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000313|Ensembl:ENSP00000470684}; Flags: Fragment;+++[M0R078_HUMAN|Unreviewed]SubName: Full=Distal membrane-arm assembly complex protein 2 {ECO:0000313|Ensembl:ENSP00000471068};"]
[55122,"'AKIRIN2'",1171,1131,1101,1134.33333333333,"04137///Mitophagy - animal+++04110///Cell cycle+++04140///Autophagy - animal+++04111///Cell cycle - yeast+++04113///Meiosis - yeast",null,"M00284///Origin recognition complex",null,"GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex+++GO:0005654///nucleoplasm","GO:0019899///enzyme binding+++GO:0005515///protein binding","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010950///positive regulation of endopeptidase activity+++GO:0007275///multicellular organism development+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032496///response to lipopolysaccharide+++GO:0008284///positive regulation of cell proliferation+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0045087///innate immune response+++GO:0010629///negative regulation of gene expression+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002376///immune system process+++GO:0045944///positive regulation of transcription by RNA polymerase II","akirin 2","[AKIR2_HUMAN|Reviewed]RecName: Full=Akirin-2;+++[Q9NW35_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10342 fis, clone NT2RM2000837 {ECO:0000313|EMBL:BAA91551.1}; Flags: Fragment;"]
[55142,"'HAUS2'",172,162.54,152.83,162.456666666667,{"$nulls":4},"GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0070652///HAUS complex+++GO:0005813///centrosome+++GO:0005876///spindle microtubule+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007098///centrosome cycle+++GO:0031023///microtubule organizing center organization+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0051225///spindle assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0000086///G2/M transition of mitotic cell cycle","HAUS augmin like complex subunit 2","[HAUS2_HUMAN|Reviewed]RecName: Full=HAUS augmin-like complex subunit 2; AltName: Full=Centrosomal protein of 27 kDa; Short=Cep27;+++[A0A024R9M5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 27kDa, isoform CRA_a {ECO:0000313|EMBL:EAW92567.1};+++[A0A024R9P0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 27kDa, isoform CRA_b {ECO:0000313|EMBL:EAW92571.1};+++[H3BP16_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 2 {ECO:0000313|Ensembl:ENSP00000455104};+++[H3BP24_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 2 {ECO:0000313|Ensembl:ENSP00000455118};+++[H3BQU2_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 2 {ECO:0000313|Ensembl:ENSP00000455942}; Flags: Fragment;+++[H3BR32_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 2 {ECO:0000313|Ensembl:ENSP00000456054};+++[H3BTG9_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 2 {ECO:0000313|Ensembl:ENSP00000457169};+++[J3QT48_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 2 {ECO:0000313|Ensembl:ENSP00000390445};+++[U3KQI5_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 2 {ECO:0000313|Ensembl:ENSP00000475909}; Flags: Fragment;"]
[55156,"'ARMC1'",353,319,292,321.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0030001///metal ion transport","armadillo repeat containing 1","[ARMC1_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing protein 1;+++[E5RHK3_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429715}; Flags: Fragment;+++[E5RJ86_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429191}; Flags: Fragment;+++[E9PR92_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000434297};"]
[55175,"'KLHL11'",119,96,91,102,{"$nulls":4},"GO:0005829///cytosol","GO:0031625///ubiquitin protein ligase binding","GO:0043687///post-translational protein modification","kelch like family member 11","[KLH11_HUMAN|Reviewed]RecName: Full=Kelch-like protein 11; Flags: Precursor;+++[A0A024R1T8_HUMAN|Unreviewed]SubName: Full=Kelch-like 11 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW60776.1};"]
[55191,"'NADSYN1'",1377,1573,1447,1465.66666666667,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways",null,"M00115///NAD biosynthesis, aspartate => NAD","R00257///Deamido-NAD+:L-glutamine amido-ligase (AMP-forming)   ATP + Deamino-NAD+ + L-Glutamine + H2O <=> AMP + Diphosphate + NAD+ + L-Glutamate","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0004359///glutaminase activity+++GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0000166///nucleotide binding+++GO:0003952///NAD+ synthase (glutamine-hydrolyzing) activity+++GO:0005515///protein binding","GO:0009435///NAD biosynthetic process+++GO:0006807///nitrogen compound metabolic process+++GO:0019674///NAD metabolic process","NAD synthetase 1","[NADE_HUMAN|Reviewed]RecName: Full=Glutamine-dependent NAD(+) synthetase; EC=6.3.5.1; AltName: Full=NAD(+) synthase [glutamine-hydrolyzing]; AltName: Full=NAD(+) synthetase;+++[A0A0B4J216_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000431820};+++[E9PKY6_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000433472};+++[E9PND0_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000437220};+++[E9PNF5_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000437172}; Flags: Fragment;+++[H0YCF9_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000431515}; Flags: Fragment;+++[H0YCQ6_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000432129}; Flags: Fragment;+++[H0YDH3_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000433612}; Flags: Fragment;+++[H0YED2_HUMAN|Unreviewed]SubName: Full=Glutamine-dependent NAD(+) synthetase {ECO:0000313|Ensembl:ENSP00000435570}; Flags: Fragment;"]
[55206,"'SBNO1'",557,567,490,538,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process","strawberry notch homolog 1","[SBNO1_HUMAN|Reviewed]RecName: Full=Protein strawberry notch homolog 1; AltName: Full=Monocyte protein 3; Short=MOP-3;"]
[55220,"'KLHDC8A'",52,40,43,45,"04140///Autophagy - animal+++03040///Spliceosome+++04137///Mitophagy - animal",null,"M00351///Spliceosome, U1-snRNP+++M00355///Spliceosome, 35S U5-snRNP+++M00398///Sm core complex+++M00352///Spliceosome, U2-snRNP+++M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0031463///Cul3-RING ubiquitin ligase complex",null,"GO:0016567///protein ubiquitination","kelch domain containing 8A","[KLD8A_HUMAN|Reviewed]RecName: Full=Kelch domain-containing protein 8A; AltName: Full=Substitute for delta-EGFR expression 1; Short=S-delta-E1;+++[A0A024R981_HUMAN|Unreviewed]SubName: Full=Kelch domain containing 8A, isoform CRA_a {ECO:0000313|EMBL:EAW91553.1};+++[U3KPW1_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 8A {ECO:0000313|Ensembl:ENSP00000475290}; Flags: Fragment;+++[U3KPX9_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 8A {ECO:0000313|Ensembl:ENSP00000475334}; Flags: Fragment;+++[U3KQC2_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 8A {ECO:0000313|Ensembl:ENSP00000475745}; Flags: Fragment;+++[U3KQH1_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 8A {ECO:0000313|Ensembl:ENSP00000475871};+++[U3KQI4_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 8A {ECO:0000313|Ensembl:ENSP00000475902}; Flags: Fragment;+++[U3KQK4_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 8A {ECO:0000313|Ensembl:ENSP00000475955}; Flags: Fragment;"]
[55240,"'STEAP3'",729,698,755,727.333333333333,"04115///p53 signaling pathway+++04216///Ferroptosis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005771///multivesicular body","GO:0005515///protein binding+++GO:0008823///cupric reductase activity+++GO:0016723///oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0052851///ferric-chelate reductase (NADPH) activity","GO:0042981///regulation of apoptotic process+++GO:0006811///ion transport+++GO:0033572///transferrin transport+++GO:0006915///apoptotic process+++GO:0015677///copper ion import+++GO:0009306///protein secretion+++GO:0098706///ferric iron import across cell outer membrane+++GO:0007049///cell cycle+++GO:0055072///iron ion homeostasis+++GO:0055114///oxidation-reduction process","STEAP3 metalloreductase","[STEA3_HUMAN|Reviewed]RecName: Full=Metalloreductase STEAP3; EC=1.16.1.-; AltName: Full=Dudulin-2; AltName: Full=Six-transmembrane epithelial antigen of prostate 3; AltName: Full=Tumor suppressor-activated pathway protein 6; Short=hTSAP6; AltName: Full=pHyde; Short=hpHyde;+++[A0A024RAD7_HUMAN|Unreviewed]SubName: Full=STEAP family member 3, isoform CRA_b {ECO:0000313|EMBL:EAW95212.1};+++[B8ZZX6_HUMAN|Unreviewed]SubName: Full=Metalloreductase STEAP3 {ECO:0000313|Ensembl:ENSP00000386510}; SubName: Full=STEAP family member 3, isoform CRA_c {ECO:0000313|EMBL:EAW95211.1};"]
[55255,"'WDR41'",199,207,252,219.333333333333,{"$nulls":4},"GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005737///cytoplasm+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0005765///lysosomal membrane","GO:0005515///protein binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0006914///autophagy+++GO:0010506///regulation of autophagy","WD repeat domain 41","[WDR41_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 41 {ECO:0000305};+++[A0A024RAK0_HUMAN|Unreviewed]SubName: Full=WD repeat domain 41, isoform CRA_a {ECO:0000313|EMBL:EAW95807.1};+++[A0A0S2Z5D8_HUMAN|Unreviewed]SubName: Full=WD repeat domain 41 isoform 2 {ECO:0000313|EMBL:ALQ34149.1}; Flags: Fragment;+++[A0A0S2Z5E0_HUMAN|Unreviewed]SubName: Full=WD repeat domain 41 isoform 1 {ECO:0000313|EMBL:ALQ34148.1}; Flags: Fragment;+++[B4DHS8_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000427652}; SubName: Full=cDNA FLJ50520, highly similar to WD repeat protein 41 {ECO:0000313|EMBL:BAG58240.1};+++[B4DK73_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000425249}; SubName: Full=cDNA FLJ50556, highly similar to WD repeat protein 41 {ECO:0000313|EMBL:BAG59085.1};+++[D6R9E7_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000422922}; Flags: Fragment;+++[D6R9M1_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000423540}; Flags: Fragment;+++[D6RA22_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000423462};+++[D6RB94_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000424327};+++[D6RBY6_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000422510}; Flags: Fragment;+++[D6RE66_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000426937}; Flags: Fragment;+++[D6RGW4_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000421166};+++[D6RH33_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000426141}; Flags: Fragment;+++[D6RIX6_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000425813};+++[D6RJA5_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000427291}; Flags: Fragment;+++[H0Y9Z3_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000425563}; Flags: Fragment;+++[H0YAA3_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000426499}; Flags: Fragment;+++[H0YAI6_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000427219}; Flags: Fragment;"]
[55258,"'THNSL2'",151,145,121,139,{"$nulls":4},"GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0030170///pyridoxal phosphate binding+++GO:0004795///threonine synthase activity+++GO:0070905///serine binding+++GO:0005125///cytokine activity+++GO:0016829///lyase activity+++GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0016311///dephosphorylation+++GO:0009071///serine family amino acid catabolic process+++GO:0010469///regulation of signaling receptor activity+++GO:0046360///2-oxobutyrate biosynthetic process","threonine synthase like 2","[THNS2_HUMAN|Reviewed]RecName: Full=Threonine synthase-like 2; Short=TSH2; EC=4.2.3.-; AltName: Full=Secreted osteoclastogenic factor of activated T-cells; Short=SOFAT;+++[A8K0C1_HUMAN|Unreviewed]SubName: Full=Threonine synthase-like 2 {ECO:0000313|Ensembl:ENSP00000366464}; SubName: Full=cDNA FLJ76990 {ECO:0000313|EMBL:BAF82175.1}; SubName: Full=cDNA, FLJ79480 {ECO:0000313|EMBL:BAF98722.1};+++[C9J3J1_HUMAN|Unreviewed]SubName: Full=Threonine synthase-like 2 {ECO:0000313|Ensembl:ENSP00000391300}; Flags: Fragment;+++[C9JU10_HUMAN|Unreviewed]SubName: Full=Threonine synthase-like 2 {ECO:0000313|Ensembl:ENSP00000407553};"]
[55289,"'ACOXL'",0,1,0,0.333333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005777///peroxisome+++GO:0005575///cellular_component+++GO:0005782///peroxisomal matrix","GO:0003674///molecular_function+++GO:0003997///acyl-CoA oxidase activity+++GO:0016402///pristanoyl-CoA oxidase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0050660///flavin adenine dinucleotide binding+++GO:0005504///fatty acid binding+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0008150///biological_process+++GO:0006635///fatty acid beta-oxidation+++GO:0055088///lipid homeostasis+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase","acyl-CoA oxidase like","[ACOXL_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A oxidase-like protein; Short=Acyl-CoA oxidase-like protein; EC=1.3.3.-;+++[A0A0C4DG10_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A oxidase-like protein {ECO:0000313|Ensembl:ENSP00000387832}; Flags: Fragment;+++[B4DU63_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59051, highly similar to Homo sapiens acyl-Coenzyme A oxidase-like (ACOXL), mRNA {ECO:0000313|EMBL:BAG62225.1};+++[C9JQI3_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A oxidase-like protein {ECO:0000313|Ensembl:ENSP00000394701}; Flags: Fragment;+++[H7C0A6_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A oxidase-like protein {ECO:0000313|Ensembl:ENSP00000393823}; Flags: Fragment;+++[H7C2M3_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A oxidase-like protein {ECO:0000313|Ensembl:ENSP00000406774}; Flags: Fragment;+++[H7C345_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A oxidase-like protein {ECO:0000313|Ensembl:ENSP00000409500}; Flags: Fragment;"]
[55301,"'OLAH'",6.01,10.24,3.76,6.67,"00061///Fatty acid biosynthesis+++01100///Metabolic pathways",null,null,"R08157///octanoyl-[acyl-carrier protein] hydrolase   Octanoyl-[acp] + H2O <=> Acyl-carrier protein + Octanoic acid+++R08158///decanoyl-[acyl-carrier protein] hydrolase   Decanoyl-[acp] + H2O <=> Acyl-carrier protein + Decanoic acid+++R04014///dodecanoyl-[acyl-carrier-protein] hydrolase   Dodecanoyl-[acyl-carrier protein] + H2O <=> Acyl-carrier protein + Dodecanoic acid","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0016295///myristoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016296///palmitoyl-[acyl-carrier-protein] hydrolase activity+++GO:0047381///dodecanoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0004320///oleoyl-[acyl-carrier-protein] hydrolase activity+++GO:0016297///acyl-[acyl-carrier-protein] hydrolase activity","GO:0051792///medium-chain fatty acid biosynthetic process+++GO:0008610///lipid biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0009058///biosynthetic process","oleoyl-ACP hydrolase","[SAST_HUMAN|Reviewed]RecName: Full=S-acyl fatty acid synthase thioesterase, medium chain; EC=3.1.2.14 {ECO:0000269|PubMed:26663084}; AltName: Full=Augmented in rheumatoid arthritis 1; Short=AURA1; AltName: Full=Oleoyl-ACP hydrolase; AltName: Full=Thioesterase 2 {ECO:0000303|PubMed:26663084}; Short=TE2 {ECO:0000303|PubMed:26663084}; AltName: Full=Thioesterase II; AltName: Full=Thioesterase domain-containing protein 1;+++[Q5VUB8_HUMAN|Unreviewed]SubName: Full=S-acyl fatty acid synthase thioesterase, medium chain {ECO:0000313|Ensembl:ENSP00000399663}; Flags: Fragment;+++[Q5VUB9_HUMAN|Unreviewed]SubName: Full=S-acyl fatty acid synthase thioesterase, medium chain {ECO:0000313|Ensembl:ENSP00000399290}; Flags: Fragment;+++[Q5VUC0_HUMAN|Unreviewed]SubName: Full=S-acyl fatty acid synthase thioesterase, medium chain {ECO:0000313|Ensembl:ENSP00000367470};+++[Q5VUC1_HUMAN|Unreviewed]SubName: Full=S-acyl fatty acid synthase thioesterase, medium chain {ECO:0000313|Ensembl:ENSP00000399449}; Flags: Fragment;"]
[553115,"'PEF1'",1129,1186.01,1052,1122.33666666667,{"$nulls":4},"GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0030127///COPII vesicle coat+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0000139///Golgi membrane","GO:0060090///molecular adaptor activity+++GO:0005515///protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0003723///RNA binding+++GO:0046983///protein dimerization activity+++GO:0005509///calcium ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046872///metal ion binding","GO:1902527///positive regulation of protein monoubiquitination+++GO:0014032///neural crest cell development+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048208///COPII vesicle coating+++GO:0014029///neural crest formation+++GO:0051592///response to calcium ion","penta-EF-hand domain containing 1","[PEF1_HUMAN|Reviewed]RecName: Full=Peflin {ECO:0000303|PubMed:10486255}; AltName: Full=PEF protein with a long N-terminal hydrophobic domain {ECO:0000303|PubMed:10486255}; AltName: Full=Penta-EF hand domain-containing protein 1 {ECO:0000312|HGNC:HGNC:30009};"]
[55323,"'LARP6'",522,487,448,485.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex","GO:0048027///mRNA 5'-UTR binding+++GO:0005515///protein binding+++GO:0035613///RNA stem-loop binding+++GO:1990825///sequence-specific mRNA binding+++GO:0003723///RNA binding+++GO:0017022///myosin binding+++GO:0003676///nucleic acid binding","GO:0006396///RNA processing+++GO:0006417///regulation of translation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0045727///positive regulation of translation+++GO:1902416///positive regulation of mRNA binding","La ribonucleoprotein domain family member 6","[LARP6_HUMAN|Reviewed]RecName: Full=La-related protein 6; AltName: Full=Acheron; Short=Achn; AltName: Full=La ribonucleoprotein domain family member 6;+++[H0YMC6_HUMAN|Unreviewed]SubName: Full=La-related protein 6 {ECO:0000313|Ensembl:ENSP00000453551}; Flags: Fragment;+++[K7EPD2_HUMAN|Unreviewed]SubName: Full=La-related protein 6 {ECO:0000313|Ensembl:ENSP00000467334}; Flags: Fragment;"]
[55344,"'PLCXD1'",186.26,245,211,214.086666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0008081///phosphoric diester hydrolase activity","GO:0006629///lipid metabolic process","phosphatidylinositol specific phospholipase C X domain containing 1","[PLCX1_HUMAN|Reviewed]RecName: Full=PI-PLC X domain-containing protein 1;+++[A0A0A0MSZ3_HUMAN|Unreviewed]SubName: Full=PI-PLC X domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000408558}; Flags: Fragment;+++[A0A0A0MT29_HUMAN|Unreviewed]SubName: Full=PI-PLC X domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000412018}; Flags: Fragment;+++[A0A0A0MT41_HUMAN|Unreviewed]SubName: Full=PI-PLC X domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000414181}; Flags: Fragment;+++[C9JP92_HUMAN|Unreviewed]SubName: Full=PI-PLC X domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000394848}; Flags: Fragment;+++[K7EIC3_HUMAN|Unreviewed]SubName: Full=PI-PLC X domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000400904}; Flags: Fragment;+++[X6RFG1_HUMAN|Unreviewed]SubName: Full=PI-PLC X domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000399510}; Flags: Fragment;"]
[5536,"'PPP5C'",913,1072,1016,1000.33333333333,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0043204///perikaryon+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:1990635///proximal dendrite+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0101031///chaperone complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0071944///cell periphery+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008289///lipid binding+++GO:0051879///Hsp90 protein binding+++GO:0031072///heat shock protein binding+++GO:0003723///RNA binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0043531///ADP binding+++GO:0016791///phosphatase activity+++GO:0048156///tau protein binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005524///ATP binding","GO:0051291///protein heterooligomerization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0070301///cellular response to hydrogen peroxide+++GO:0060548///negative regulation of cell death+++GO:0043278///response to morphine+++GO:0006470///protein dephosphorylation+++GO:0051259///protein complex oligomerization+++GO:0006351///transcription, DNA-templated+++GO:0006281///DNA repair+++GO:1904550///response to arachidonic acid+++GO:1901215///negative regulation of neuron death+++GO:0071276///cellular response to cadmium ion+++GO:2000324///positive regulation of glucocorticoid receptor signaling pathway+++GO:0000278///mitotic cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0010288///response to lead ion+++GO:0016576///histone dephosphorylation+++GO:0000165///MAPK cascade","protein phosphatase 5 catalytic subunit","[PPP5_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 5; Short=PP5; EC=3.1.3.16; AltName: Full=Protein phosphatase T; Short=PP-T; Short=PPT;+++[A0A024R0Q7_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[A8MU39_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[H0YDU8_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[Q9BPW0_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;"]
[55422,"'ZNF331'",176,194,183,184.333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 331","[ZN331_HUMAN|Reviewed]RecName: Full=Zinc finger protein 331; AltName: Full=C2H2-like zinc finger protein rearranged in thyroid adenomas; AltName: Full=Zinc finger protein 361; AltName: Full=Zinc finger protein 463;+++[A0A024R4J5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331, isoform CRA_a {ECO:0000313|EMBL:EAW72147.1};+++[D6RH27_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000426155}; Flags: Fragment;+++[E7ENR0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000423263}; Flags: Fragment;+++[E7EPG5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000426458};+++[E7EPT0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000426127}; Flags: Fragment;+++[E7ERM8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000422471}; Flags: Fragment;+++[E7ETJ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000427532}; Flags: Fragment;+++[E7EV14_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000423675}; Flags: Fragment;+++[E7EWU7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000424835}; Flags: Fragment;+++[Q68D63_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686L0787 {ECO:0000313|EMBL:CAH18357.1};+++[Q6PK05_HUMAN|Unreviewed]SubName: Full=ZNF331 protein {ECO:0000313|EMBL:AAH09365.1}; Flags: Fragment;+++[Q71QC3_HUMAN|Unreviewed]SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAQ03251.1}; Flags: Fragment;+++[Q71QC4_HUMAN|Unreviewed]SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAQ03250.1}; Flags: Fragment;+++[Q71QC5_HUMAN|Unreviewed]SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAQ03249.1}; SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000422586}; Flags: Fragment;+++[Q71QC6_HUMAN|Unreviewed]SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAQ03248.1}; SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000425517}; Flags: Fragment;+++[Q71QC8_HUMAN|Unreviewed]SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAQ03246.1}; Flags: Fragment;+++[Q71QC9_HUMAN|Unreviewed]SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAQ03245.1}; SubName: Full=Zinc finger protein 331 {ECO:0000313|Ensembl:ENSP00000424929}; Flags: Fragment;"]
[55505,"'NOP10'",906,727,771,801.333333333333,"03008///Ribosome biogenesis in eukaryotes","H00507///Dyskeratosis congenita (DC)","M00425///H/ACA ribonucleoprotein complex",null,"GO:0031429///box H/ACA snoRNP complex+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0072589///box H/ACA scaRNP complex+++GO:0090661///box H/ACA telomerase RNP complex+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005730///nucleolus+++GO:0005697///telomerase holoenzyme complex+++GO:0005654///nucleoplasm+++GO:0015030///Cajal body","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:0034513///box H/ACA snoRNA binding+++GO:0070034///telomerase RNA binding+++GO:0005515///protein binding","GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0031118///rRNA pseudouridine synthesis+++GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0031120///snRNA pseudouridine synthesis+++GO:0007004///telomere maintenance via telomerase+++GO:0042254///ribosome biogenesis+++GO:0001522///pseudouridine synthesis+++GO:0006364///rRNA processing","NOP10 ribonucleoprotein","[NOP10_HUMAN|Reviewed]RecName: Full=H/ACA ribonucleoprotein complex subunit 3; AltName: Full=Nucleolar protein 10; AltName: Full=Nucleolar protein family A member 3; AltName: Full=snoRNP protein NOP10;+++[H0YM60_HUMAN|Unreviewed]SubName: Full=H/ACA ribonucleoprotein complex subunit 3 {ECO:0000313|Ensembl:ENSP00000453475};"]
[55526,"'DHTKD1'",437,478,431,448.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005759///mitochondrial matrix+++GO:0005829///cytosol+++GO:0045252///oxoglutarate dehydrogenase complex+++GO:0005739///mitochondrion","GO:0030976///thiamine pyrophosphate binding+++GO:0004591///oxoglutarate dehydrogenase (succinyl-transferring) activity+++GO:0016624///oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0006099///tricarboxylic acid cycle+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006096///glycolytic process+++GO:0006091///generation of precursor metabolites and energy","dehydrogenase E1 and transketolase domain containing 1","[DHTK1_HUMAN|Reviewed]RecName: Full=Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial; EC=1.2.4.2; AltName: Full=Dehydrogenase E1 and transketolase domain-containing protein 1; Flags: Precursor;+++[C9JWN1_HUMAN|Unreviewed]SubName: Full=Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial {ECO:0000313|Ensembl:ENSP00000388163}; Flags: Fragment;+++[H7C149_HUMAN|Unreviewed]SubName: Full=Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial {ECO:0000313|Ensembl:ENSP00000398482}; Flags: Fragment;+++[H7C1J3_HUMAN|Unreviewed]SubName: Full=Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial {ECO:0000313|Ensembl:ENSP00000400625}; Flags: Fragment;"]
[55571,"'CNOT11'",992,1020,1031,1014.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0008283///cell proliferation+++GO:0006417///regulation of translation+++GO:0031047///gene silencing by RNA+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening","CCR4-NOT transcription complex subunit 11","[CNO11_HUMAN|Reviewed]RecName: Full=CCR4-NOT transcription complex subunit 11;+++[H7C0C7_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 11 {ECO:0000313|Ensembl:ENSP00000394203}; Flags: Fragment;"]
[55586,"'MIOX'",0,1,0,0.333333333333333,"00562///Inositol phosphate metabolism+++00053///Ascorbate and aldarate metabolism",null,null,"R01184///myo-Inositol:oxygen oxidoreductase   myo-Inositol + Oxygen <=> D-Glucuronate + H2O","GO:0005829///cytosol+++GO:0016234///inclusion body+++GO:0005737///cytoplasm","GO:0016491///oxidoreductase activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0046872///metal ion binding+++GO:0050113///inositol oxygenase activity+++GO:0016701///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen+++GO:0008199///ferric iron binding+++GO:0005506///iron ion binding+++GO:0016651///oxidoreductase activity, acting on NAD(P)H","GO:0019310///inositol catabolic process+++GO:0043647///inositol phosphate metabolic process+++GO:0055114///oxidation-reduction process","myo-inositol oxygenase","[MIOX_HUMAN|Reviewed]RecName: Full=Inositol oxygenase; EC=1.13.99.1; AltName: Full=Aldehyde reductase-like 6; AltName: Full=Kidney-specific protein 32; AltName: Full=Myo-inositol oxygenase; Short=MI oxygenase; AltName: Full=Renal-specific oxidoreductase;+++[A6PVH2_HUMAN|Unreviewed]SubName: Full=Inositol oxygenase {ECO:0000313|Ensembl:ENSP00000379081}; SubName: Full=Myo-inositol oxygenase, isoform CRA_c {ECO:0000313|EMBL:EAW73546.1};+++[A6PVH4_HUMAN|Unreviewed]SubName: Full=Inositol oxygenase {ECO:0000313|Ensembl:ENSP00000409894}; Flags: Fragment;"]
[55609,"'ZNF280C'",38,54,51,47.6666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 280C","[Z280C_HUMAN|Reviewed]RecName: Full=Zinc finger protein 280C; AltName: Full=Suppressor of hairy wing homolog 3; AltName: Full=Zinc finger protein 633;+++[Q9UJJ2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 280C {ECO:0000313|Ensembl:ENSP00000408521}; Flags: Fragment;"]
[55634,"'KRBOX4'",110.02,100.16,86.71,98.9633333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005622///intracellular+++GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","KRAB box domain containing 4","[KRBX4_HUMAN|Reviewed]RecName: Full=KRAB domain-containing protein 4; AltName: Full=KRAB box domain-containing protein 4;+++[A0A024R175_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 673, isoform CRA_a {ECO:0000313|EMBL:EAW59262.1};+++[C9J804_HUMAN|Unreviewed]SubName: Full=KRAB domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000418205}; Flags: Fragment;+++[C9J950_HUMAN|Unreviewed]SubName: Full=KRAB domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000418146};"]
[55643,"'BTBD2'",2976,3180,2943,3033,{"$nulls":4},"GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0022008///neurogenesis","BTB domain containing 2","[BTBD2_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein 2;+++[A0A087WUX2_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000478992}; Flags: Fragment;+++[A0A087WXN3_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000481163}; Flags: Fragment;+++[A0A087WY57_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000481529}; Flags: Fragment;+++[A0A087X147_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000483892}; Flags: Fragment;+++[K7EMW9_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000466686}; Flags: Fragment;+++[K7ENV9_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000467113}; Flags: Fragment;+++[Q6NT96_HUMAN|Unreviewed]SubName: Full=BTBD2 protein {ECO:0000313|EMBL:AAH69199.1}; Flags: Fragment;"]
[55656,"'INTS8'",389.13,280.01,270,313.046666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0016180///snRNA processing+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0034472///snRNA 3'-end processing","integrator complex subunit 8","[INT8_HUMAN|Reviewed]RecName: Full=Integrator complex subunit 8; Short=Int8; AltName: Full=Protein kaonashi-1;+++[E5RG48_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000427840};+++[E5RH10_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430033}; Flags: Fragment;+++[E5RIN8_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000429340}; Flags: Fragment;+++[E5RJF0_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000428260}; Flags: Fragment;+++[E5RJL5_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000429056}; Flags: Fragment;+++[H0YBQ1_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430049}; Flags: Fragment;+++[H0YBS1_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430180}; Flags: Fragment;+++[H0YC12_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430722}; Flags: Fragment;+++[J3KNV5_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000343274};"]
[55679,"'LIMS2'",1003,805,755,854.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0045216///cell-cell junction organization+++GO:0034329///cell junction assembly+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:0098609///cell-cell adhesion+++GO:0043066///negative regulation of apoptotic process+++GO:2000346///negative regulation of hepatocyte proliferation+++GO:2001046///positive regulation of integrin-mediated signaling pathway","LIM zinc finger domain containing 2","[LIMS2_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 2; AltName: Full=LIM-like protein 2; AltName: Full=Particularly interesting new Cys-His protein 2; Short=PINCH-2;+++[A0A024RAH1_HUMAN|Unreviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein {ECO:0000256|PIRNR:PIRNR038003};+++[A0A024RAI9_HUMAN|Unreviewed]SubName: Full=LIM and senescent cell antigen-like domains 2, isoform CRA_b {ECO:0000313|EMBL:EAW95329.1}; Flags: Fragment;+++[A0PJ44_HUMAN|Unreviewed]SubName: Full=LIMS2 protein {ECO:0000313|EMBL:AAH08977.1}; Flags: Fragment;+++[B3KNZ3_HUMAN|Unreviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein {ECO:0000256|PIRNR:PIRNR038003};+++[F8WEF3_HUMAN|Unreviewed]SubName: Full=LIM and senescent cell antigen-like-containing domain protein 2 {ECO:0000313|Ensembl:ENSP00000388611};+++[H0Y592_HUMAN|Unreviewed]SubName: Full=LIM and senescent cell antigen-like-containing domain protein 2 {ECO:0000313|Ensembl:ENSP00000397253}; Flags: Fragment;+++[Q53RZ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LIMS2 {ECO:0000313|EMBL:AAX93074.1}; Flags: Fragment;"]
[55697,"'VAC14'",2095,2271,2005,2123.66666666667,"05166///HTLV-I infection+++05203///Viral carcinogenesis",{"$nulls":3},"GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0010008///endosome membrane+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0000306///extrinsic component of vacuolar membrane+++GO:0031090///organelle membrane+++GO:0070772///PAS complex+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005768///endosome","GO:0005515///protein binding+++GO:0038023///signaling receptor activity","GO:0006661///phosphatidylinositol biosynthetic process+++GO:0007165///signal transduction+++GO:0016032///viral process","Vac14, PIKFYVE complex component","[VAC14_HUMAN|Reviewed]RecName: Full=Protein VAC14 homolog; AltName: Full=Tax1-binding protein 2;+++[A0A087WT26_HUMAN|Unreviewed]SubName: Full=Protein VAC14 homolog {ECO:0000313|Ensembl:ENSP00000477536}; Flags: Fragment;+++[H3BN23_HUMAN|Unreviewed]SubName: Full=Protein VAC14 homolog {ECO:0000313|Ensembl:ENSP00000454650};+++[H3BQD9_HUMAN|Unreviewed]SubName: Full=Protein VAC14 homolog {ECO:0000313|Ensembl:ENSP00000455731}; Flags: Fragment;+++[H3BUU8_HUMAN|Unreviewed]SubName: Full=Protein VAC14 homolog {ECO:0000313|Ensembl:ENSP00000457809};+++[J3QLC3_HUMAN|Unreviewed]SubName: Full=Protein VAC14 homolog {ECO:0000313|Ensembl:ENSP00000463485}; Flags: Fragment;"]
[5571,"'PRKAG1'",716,652,615,661,"04213///Longevity regulating pathway - multiple species+++04152///AMPK signaling pathway+++05410///Hypertrophic cardiomyopathy (HCM)+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04530///Tight junction+++04068///FoxO signaling pathway+++04211///Longevity regulating pathway+++04921///Oxytocin signaling pathway+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04371///Apelin signaling pathway+++04714///Thermogenesis+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04710///Circadian rhythm","H00292///Hypertrophic cardiomyopathy (HCM)+++H01154///Wolff-Parkinson-White (WPW) syndrome+++H00069///Glycogen storage diseases (GSD)+++H01956///Glycogen storage disease of heart",null,null,"GO:0031588///nucleotide-activated protein kinase complex+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0004691///cAMP-dependent protein kinase activity+++GO:0032559///adenyl ribonucleotide binding+++GO:0004672///protein kinase activity+++GO:0004679///AMP-activated protein kinase activity+++GO:0043531///ADP binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016208///AMP binding+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0019901///protein kinase binding","GO:0006633///fatty acid biosynthetic process+++GO:0007165///signal transduction+++GO:0071900///regulation of protein serine/threonine kinase activity+++GO:0051170///import into nucleus+++GO:0006631///fatty acid metabolic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0010628///positive regulation of gene expression+++GO:0006110///regulation of glycolytic process+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0007050///cell cycle arrest+++GO:0016236///macroautophagy+++GO:0007283///spermatogenesis+++GO:0006629///lipid metabolic process","protein kinase AMP-activated non-catalytic subunit gamma 1","[AAKG1_HUMAN|Reviewed]RecName: Full=5'-AMP-activated protein kinase subunit gamma-1; Short=AMPK gamma1; Short=AMPK subunit gamma-1; Short=AMPKg;+++[A0A024R125_HUMAN|Unreviewed]SubName: Full=Protein kinase, AMP-activated, gamma 1 non-catalytic subunit, isoform CRA_a {ECO:0000313|EMBL:EAW58033.1};+++[F8VPF5_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000450112}; Flags: Fragment;+++[F8VQQ1_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000450273}; Flags: Fragment;+++[F8VRY2_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000448739}; Flags: Fragment;+++[F8VSH3_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000448290}; Flags: Fragment;+++[F8VSL2_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000448251}; Flags: Fragment;+++[F8VVA3_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000449637}; Flags: Fragment;+++[F8VYY9_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000448873};+++[F8VYZ8_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000449104}; Flags: Fragment;+++[F8VZX1_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000447671}; Flags: Fragment;+++[F8W046_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000447637};+++[H0YHF8_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000446987}; Flags: Fragment;+++[H0YIC9_HUMAN|Unreviewed]SubName: Full=5'-AMP-activated protein kinase subunit gamma-1 {ECO:0000313|Ensembl:ENSP00000449121}; Flags: Fragment;"]
[55732,"'C1orf112'",39,39,33,37,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium","GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0016477///cell migration","chromosome 1 open reading frame 112","[CA112_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C1orf112;+++[A0A024R922_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 112, isoform CRA_a {ECO:0000313|EMBL:EAW90864.1};+++[A0A1B0GTJ9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf112 {ECO:0000313|Ensembl:ENSP00000489730};+++[A0A1B0GUP7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf112 {ECO:0000313|Ensembl:ENSP00000490194};+++[A0A1B0GV14_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf112 {ECO:0000313|Ensembl:ENSP00000490333};+++[B4E0A9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60381 {ECO:0000313|EMBL:BAG64371.1};"]
[55748,"'CNDP2'",1328,1622,1400,1450,"01100///Metabolic pathways+++00410///beta-Alanine metabolism+++00330///Arginine and proline metabolism+++00340///Histidine metabolism",null,null,"R01992///alpha-Aminobutyryl histidine hydrolase   Homocarnosine + H2O <=> 4-Aminobutanoate + L-Histidine+++R01166///Nalpha-(beta-alanyl)-L-histidine hydrolase   Carnosine + H2O <=> beta-Alanine + L-Histidine","GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0004180///carboxypeptidase activity+++GO:0103046///alanylglutamate dipeptidase activity+++GO:0008233///peptidase activity+++GO:0102008///cytosolic dipeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity+++GO:0046872///metal ion binding","GO:0006508///proteolysis+++GO:0006750///glutathione biosynthetic process","carnosine dipeptidase 2","[CNDP2_HUMAN|Reviewed]RecName: Full=Cytosolic non-specific dipeptidase; EC=3.4.13.18; AltName: Full=CNDP dipeptidase 2; AltName: Full=Carnosine dipeptidase II {ECO:0000303|PubMed:25964343}; AltName: Full=Epididymis secretory protein Li 13 {ECO:0000312|EMBL:ACJ13654.1}; AltName: Full=Glutamate carboxypeptidase-like protein 1; AltName: Full=Peptidase A;+++[A0A024R382_HUMAN|Unreviewed]SubName: Full=CNDP dipeptidase 2 (Metallopeptidase M20 family), isoform CRA_d {ECO:0000313|EMBL:EAW66558.1};+++[A0A087WVS2_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000479635}; Flags: Fragment;+++[A0A087WYZ1_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000482227};+++[J3KRD5_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000461941}; Flags: Fragment;+++[J3KRJ8_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000462034}; Flags: Fragment;+++[J3KSS4_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000462626}; Flags: Fragment;+++[J3KSV5_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000462673}; Flags: Fragment;+++[J3QKQ0_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000463182}; Flags: Fragment;+++[J3QKT2_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000463222}; Flags: Fragment;+++[J3QL02_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000463314}; Flags: Fragment;+++[J3QLU1_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000463702}; Flags: Fragment;+++[J3QQN6_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000463816}; Flags: Fragment;+++[J3QR27_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000464014}; Flags: Fragment;+++[J3QRA8_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000464122}; Flags: Fragment;+++[J3QRD0_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000464151}; Flags: Fragment;+++[J3QRH4_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000464214}; Flags: Fragment;+++[J3QRP4_HUMAN|Unreviewed]SubName: Full=Cytosolic non-specific dipeptidase {ECO:0000313|Ensembl:ENSP00000464319};+++[L8EAZ5_HUMAN|Unreviewed]SubName: Full=Alternative protein CNDP2 {ECO:0000313|EMBL:CCQ43593.1};"]
[55764,"'IFT122'",995,1174,1045,1071.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00529///Cranioectodermal dysplasia",null,null,"GO:0042995///cell projection+++GO:0036064///ciliary basal body+++GO:0005856///cytoskeleton+++GO:0030991///intraciliary transport particle A+++GO:0097546///ciliary base+++GO:0005929///cilium+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0032391///photoreceptor connecting cilium+++GO:0097542///ciliary tip","GO:0005515///protein binding","GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0035720///intraciliary anterograde transport+++GO:0035721///intraciliary retrograde transport+++GO:0060173///limb development+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0030030///cell projection organization+++GO:0048593///camera-type eye morphogenesis+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0072594///establishment of protein localization to organelle+++GO:0010172///embryonic body morphogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007275///multicellular organism development+++GO:0042733///embryonic digit morphogenesis+++GO:1905515///non-motile cilium assembly+++GO:0035050///embryonic heart tube development+++GO:0060830///ciliary receptor clustering involved in smoothened signaling pathway+++GO:0061512///protein localization to cilium+++GO:0009953///dorsal/ventral pattern formation+++GO:0007227///signal transduction downstream of smoothened+++GO:0001843///neural tube closure+++GO:0060271///cilium assembly+++GO:0021914///negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0035735///intraciliary transport involved in cilium assembly","intraflagellar transport 122","[IF122_HUMAN|Reviewed]RecName: Full=Intraflagellar transport protein 122 homolog; AltName: Full=WD repeat-containing protein 10; AltName: Full=WD repeat-containing protein 140;+++[B3KUD1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39572 fis, clone SKMUS2002153, highly similar to Intraflagellar transport 122 homolog {ECO:0000313|EMBL:BAG53393.1};+++[B4DST2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54525, highly similar to Intraflagellar transport 122 homolog {ECO:0000313|EMBL:BAG61744.1};+++[D6R8Z2_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000422237}; Flags: Fragment;+++[D6RAF7_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000421953};+++[D6RIB5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000427515}; Flags: Fragment;+++[H0Y8I2_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000421140}; Flags: Fragment;+++[H0Y978_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000423288}; Flags: Fragment;+++[H0Y9E1_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000423902}; Flags: Fragment;+++[H0Y9E5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000423921}; Flags: Fragment;+++[H0Y9I6_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000424206}; Flags: Fragment;+++[H0Y9Q2_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000424727}; Flags: Fragment;+++[H0Y9Y9_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000425540}; Flags: Fragment;+++[H0YAG6_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000427027}; Flags: Fragment;+++[H0YAG9_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 122 homolog {ECO:0000313|Ensembl:ENSP00000427061}; Flags: Fragment;+++[L8E937_HUMAN|Unreviewed]SubName: Full=Alternative protein IFT122 {ECO:0000313|EMBL:CCQ43810.1};"]
[55780,"'ERMARD'",141,125,134,133.333333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0007275///multicellular organism development","ER membrane associated RNA degradation","[EMARD_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein; Short=ER membrane-associated RNA degradation protein;+++[K7EM31_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein {ECO:0000313|Ensembl:ENSP00000466335}; Flags: Fragment;+++[K7EME8_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein {ECO:0000313|Ensembl:ENSP00000466474}; Flags: Fragment;+++[K7EMW5_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein {ECO:0000313|Ensembl:ENSP00000466679}; Flags: Fragment;+++[K7EPX8_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein {ECO:0000313|Ensembl:ENSP00000467582};+++[K7ER62_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein {ECO:0000313|Ensembl:ENSP00000468124}; Flags: Fragment;+++[K7ERF7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein {ECO:0000313|Ensembl:ENSP00000468240};+++[K7ESI0_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane-associated RNA degradation protein {ECO:0000313|Ensembl:ENSP00000468722}; Flags: Fragment;"]
[55798,"'METTL2B'",284.63,232.32,198.26,238.403333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0016427///tRNA (cytosine) methyltransferase activity+++GO:0016740///transferase activity+++GO:0052735///tRNA (cytosine-3-)-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0032259///methylation+++GO:0030488///tRNA methylation","methyltransferase like 2B","[MET2B_HUMAN|Reviewed]RecName: Full=Methyltransferase-like protein 2B; EC=2.1.1.-;+++[F8WAS9_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 2B {ECO:0000313|Ensembl:ENSP00000417616};+++[H7C2C8_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 2B {ECO:0000313|Ensembl:ENSP00000405144}; Flags: Fragment;+++[H7C552_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 2B {ECO:0000313|Ensembl:ENSP00000418989}; Flags: Fragment;"]
[55815,"'TSNAXIP1'",34,53,59,48.6666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0007283///spermatogenesis+++GO:0008150///biological_process","translin associated factor X interacting protein 1","[TXIP1_HUMAN|Reviewed]RecName: Full=Translin-associated factor X-interacting protein 1; Short=Trax-interacting protein 1;+++[A0A024R6Y0_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X interacting protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW83177.1};+++[B4DXD0_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000457241}; SubName: Full=cDNA FLJ56264, highly similar to Homo sapiens translin-associated factor X interacting protein 1 (TSNAXIP1), mRNA {ECO:0000313|EMBL:BAG63342.1};+++[E7ENJ7_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000411472};+++[H3BNS9_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000454989}; Flags: Fragment;+++[H3BNU6_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000455011};+++[H3BQ72_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000455640};+++[I3L1M2_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000458938};+++[J3KQF4_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000397147}; Flags: Fragment;+++[J3QQL6_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000463792}; Flags: Fragment;+++[J3QS50_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000464527}; Flags: Fragment;+++[J3QSH8_HUMAN|Unreviewed]SubName: Full=Translin-associated factor X-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000464694}; Flags: Fragment;"]
[55837,"'EAPP'",536,431,479,482,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm",null,"GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0008284///positive regulation of cell proliferation","E2F associated phosphoprotein","[EAPP_HUMAN|Reviewed]RecName: Full=E2F-associated phosphoprotein; Short=EAPP;+++[A0A087X060_HUMAN|Unreviewed]SubName: Full=E2F-associated phosphoprotein {ECO:0000313|Ensembl:ENSP00000483122};+++[G3V2W9_HUMAN|Unreviewed]SubName: Full=E2F-associated phosphoprotein {ECO:0000313|Ensembl:ENSP00000450908}; Flags: Fragment;+++[G3V5N6_HUMAN|Unreviewed]SubName: Full=E2F-associated phosphoprotein {ECO:0000313|Ensembl:ENSP00000452439};+++[L8EAZ8_HUMAN|Unreviewed]SubName: Full=Alternative protein EAPP {ECO:0000313|EMBL:CCQ43598.1};"]
[55852,"'TEX2'",5853.99,6081,5314.24,5749.74333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008289///lipid binding+++GO:0003674///molecular_function","GO:0007165///signal transduction+++GO:0006869///lipid transport+++GO:0006665///sphingolipid metabolic process","testis expressed 2","[TEX2_HUMAN|Reviewed]RecName: Full=Testis-expressed protein 2; AltName: Full=Transmembrane protein 96;+++[A0A087WVA8_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000479308};+++[J3KRY2_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000462210}; Flags: Fragment;+++[J3KRZ8_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000462230}; Flags: Fragment;+++[J3QKY0_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000463286}; Flags: Fragment;+++[Q2YDX6_HUMAN|Unreviewed]SubName: Full=TEX2 protein {ECO:0000313|EMBL:AAI08280.1}; Flags: Fragment;+++[Q7L166_HUMAN|Unreviewed]SubName: Full=TEX2 protein {ECO:0000313|EMBL:AAH33661.2}; Flags: Fragment;"]
[55876,"'GSDMB'",17,17,15,16.3333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0001786///phosphatidylserine binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0012501///programmed cell death+++GO:0070269///pyroptosis","gasdermin B","[GSDMB_HUMAN|Reviewed]RecName: Full=Gasdermin-B; AltName: Full=Gasdermin-like protein;+++[B2CM70_HUMAN|Unreviewed]SubName: Full=Gasdermin-like isoform GSDML1 {ECO:0000313|EMBL:ACB37349.1};+++[B2CM71_HUMAN|Unreviewed]SubName: Full=Gasdermin-B {ECO:0000313|Ensembl:ENSP00000428712}; SubName: Full=Gasdermin-like isoform GSDML2 {ECO:0000313|EMBL:ACB37350.1};+++[B2CM72_HUMAN|Unreviewed]SubName: Full=Gasdermin-B {ECO:0000313|Ensembl:ENSP00000429265}; SubName: Full=Gasdermin-like isoform GSDML3 {ECO:0000313|EMBL:ACB37351.1};+++[B2CM73_HUMAN|Unreviewed]SubName: Full=Gasdermin-B {ECO:0000313|Ensembl:ENSP00000428217}; SubName: Full=Gasdermin-like isoform GSDML4 {ECO:0000313|EMBL:ACB37352.1};+++[J3QLF0_HUMAN|Unreviewed]SubName: Full=Gasdermin-B {ECO:0000313|Ensembl:ENSP00000463519}; Flags: Fragment;"]
[55905,"'RNF114'",516,473,436,475,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005737///cytoplasm","GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity","GO:0000209///protein polyubiquitination+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation","ring finger protein 114","[RN114_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF114; EC=2.3.2.27; AltName: Full=RING finger protein 114; AltName: Full=RING-type E3 ubiquitin transferase RNF114 {ECO:0000305}; AltName: Full=Zinc finger protein 228; AltName: Full=Zinc finger protein 313;+++[A0A096LNN8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF114 {ECO:0000313|Ensembl:ENSP00000485136};+++[A0A096LNT1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF114 {ECO:0000313|Ensembl:ENSP00000485203};+++[A0A096LNV3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF114 {ECO:0000313|Ensembl:ENSP00000485239}; Flags: Fragment;+++[A0A096LP02_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF114 {ECO:0000313|Ensembl:ENSP00000485317};+++[A0A096LPF9_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF114 {ECO:0000313|Ensembl:ENSP00000485575};+++[H0UI65_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 313, isoform CRA_b {ECO:0000313|EMBL:EAW75644.1};"]
[55922,"'NKRF'",204,197,201,200.666666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II","NFKB repressing factor","[NKRF_HUMAN|Reviewed]RecName: Full=NF-kappa-B-repressing factor; Short=NFkB-repressing factor; AltName: Full=Protein ITBA4; AltName: Full=Transcription factor NRF;+++[A1Z1A7_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABM16955.1}; Flags: Fragment;+++[A2I827_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABM55375.1}; Flags: Fragment;+++[A2I828_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABM55376.1}; Flags: Fragment;+++[A2I829_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABM55377.1}; Flags: Fragment;+++[A2I830_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABM55378.1}; Flags: Fragment;+++[A2I831_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABM55379.1}; Flags: Fragment;+++[A2I832_HUMAN|Unreviewed]SubName: Full=Truncated NF-kappaB repressing factor {ECO:0000313|EMBL:ABM55380.1}; Flags: Fragment;+++[A3F768_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABN11234.1};+++[A3F769_HUMAN|Unreviewed]SubName: Full=NF-kappaB repressing factor {ECO:0000313|EMBL:ABN11235.1}; SubName: Full=NF-kappaB repressing factor, isoform CRA_b {ECO:0000313|EMBL:EAW89860.1};+++[Q6NUN2_HUMAN|Unreviewed]SubName: Full=NFKB repressing factor {ECO:0000313|EMBL:AAH68514.1};"]
[55971,"'BAIAP2L1'",556,588,514,552.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005913///cell-cell adherens junction","GO:0005515///protein binding+++GO:0070064///proline-rich region binding+++GO:0003779///actin binding+++GO:0098641///cadherin binding involved in cell-cell adhesion","GO:0046626///regulation of insulin receptor signaling pathway+++GO:0051017///actin filament bundle assembly+++GO:0030838///positive regulation of actin filament polymerization+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0007009///plasma membrane organization+++GO:0051764///actin crosslink formation+++GO:0030833///regulation of actin filament polymerization+++GO:0098609///cell-cell adhesion+++GO:0009617///response to bacterium","BAI1 associated protein 2 like 1","[BI2L1_HUMAN|Reviewed]RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1; Short=BAI1-associated protein 2-like protein 1; AltName: Full=Insulin receptor tyrosine kinase substrate;"]
[5601,"'MAPK9'",424,418,410,417.333333333333,"04931///Insulin resistance+++05212///Pancreatic cancer+++04910///Insulin signaling pathway+++04920///Adipocytokine signaling pathway+++04214///Apoptosis - fly+++04657///IL-17 signaling pathway+++01522///Endocrine resistance+++04620///Toll-like receptor signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04510///Focal adhesion+++05132///Salmonella infection+++05200///Pathways in cancer+++04212///Longevity regulating pathway - worm+++05160///Hepatitis C+++04622///RIG-I-like receptor signaling pathway+++04658///Th1 and Th2 cell differentiation+++04917///Prolactin signaling pathway+++04010///MAPK signaling pathway+++04659///Th17 cell differentiation+++04210///Apoptosis+++04750///Inflammatory mediator regulation of TRP channels+++04926///Relaxin signaling pathway+++04668///TNF signaling pathway+++04530///Tight junction+++05145///Toxoplasmosis+++05133///Pertussis+++04664///Fc epsilon RI signaling pathway+++04728///Dopaminergic synapse+++04140///Autophagy - animal+++05142///Chagas disease (American trypanosomiasis)+++04215///Apoptosis - multiple species+++04068///FoxO signaling pathway+++04310///Wnt signaling pathway+++04624///Toll and Imd signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04380///Osteoclast differentiation+++04912///GnRH signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04723///Retrograde endocannabinoid signaling+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04625///C-type lectin receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04014///Ras signaling pathway+++05231///Choline metabolism in cancer+++04217///Necroptosis+++04141///Protein processing in endoplasmic reticulum+++04722///Neurotrophin signaling pathway+++05169///Epstein-Barr virus infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04013///MAPK signaling pathway - fly+++05168///Herpes simplex infection+++04933///AGE-RAGE signaling pathway in diabetic complications+++04137///Mitophagy - animal+++04930///Type II diabetes mellitus+++05131///Shigellosis+++05152///Tuberculosis+++05161///Hepatitis B+++05164///Influenza A+++04024///cAMP signaling pathway+++04391///Hippo signaling pathway - fly+++04071///Sphingolipid signaling pathway+++05210///Colorectal cancer+++04012///ErbB signaling pathway","H00606///Early infantile epileptic encephalopathy","M00688///MAPK (JNK) signaling",null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0004707///MAP kinase activity+++GO:0000166///nucleotide binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0004705///JUN kinase activity+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity","GO:0018105///peptidyl-serine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0016310///phosphorylation+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:1901485///positive regulation of transcription factor catabolic process+++GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade+++GO:0043065///positive regulation of apoptotic process+++GO:0048666///neuron development+++GO:0046686///response to cadmium ion+++GO:0034614///cellular response to reactive oxygen species+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0009612///response to mechanical stimulus+++GO:0010468///regulation of gene expression+++GO:0071803///positive regulation of podosome assembly+++GO:0031398///positive regulation of protein ubiquitination+++GO:0071276///cellular response to cadmium ion+++GO:0042752///regulation of circadian rhythm+++GO:0010628///positive regulation of gene expression+++GO:0061833///protein localization to tricellular tight junction+++GO:0007254///JNK cascade+++GO:0071310///cellular response to organic substance+++GO:0048511///rhythmic process+++GO:0007258///JUN phosphorylation","mitogen-activated protein kinase 9","[MK09_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase 9; Short=MAP kinase 9; Short=MAPK 9; EC=2.7.11.24 {ECO:0000269|PubMed:11062067, ECO:0000269|PubMed:15805466, ECO:0000269|PubMed:17875713, ECO:0000269|PubMed:21110917, ECO:0000269|PubMed:7969172, ECO:0000269|PubMed:8001819, ECO:0000269|PubMed:8654373}; AltName: Full=JNK-55; AltName: Full=Stress-activated protein kinase 1a; Short=SAPK1a; AltName: Full=Stress-activated protein kinase JNK2; AltName: Full=c-Jun N-terminal kinase 2;+++[B5BUJ7_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|SAAS:SAAS00652812}; Flags: Fragment;+++[D7R525_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|SAAS:SAAS00652812};+++[D7R526_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|SAAS:SAAS00652812};+++[D7R527_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|SAAS:SAAS00652812};+++[D7R528_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 9 isoform JNK2 alpha 4 {ECO:0000313|EMBL:ADH10368.1};+++[E5RJ57_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 9 {ECO:0000313|Ensembl:ENSP00000430608}; Flags: Fragment;+++[J3KNK1_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|SAAS:SAAS00652812};"]
[56098,"'PCDHGC4'",57.38,57.85,49.46,54.8966666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0050808///synapse organization+++GO:0007155///cell adhesion","protocadherin gamma subfamily C, 4","[PCDGL_HUMAN|Reviewed]RecName: Full=Protocadherin gamma-C4; Short=PCDH-gamma-C4; Flags: Precursor;+++[A0A087WU59_HUMAN|Unreviewed]SubName: Full=Protocadherin gamma-C4 {ECO:0000313|Ensembl:ENSP00000478393}; Flags: Fragment;+++[A0A087WUC2_HUMAN|Unreviewed]SubName: Full=Protocadherin gamma-C4 {ECO:0000313|Ensembl:ENSP00000478541};+++[A4FU17_HUMAN|Unreviewed]SubName: Full=PCDHGC4 protein {ECO:0000313|EMBL:AAI01037.1}; Flags: Fragment;"]
[56103,"'PCDHGB2'",155.56,193.75,83.78,144.363333333333,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","protocadherin gamma subfamily B, 2","[PCDGE_HUMAN|Reviewed]RecName: Full=Protocadherin gamma-B2; Short=PCDH-gamma-B2; Flags: Precursor;"]
[56132,"'PCDHB3'",75.94,76.44,66.24,72.8733333333333,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0007416///synapse assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0007399///nervous system development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007268///chemical synaptic transmission","protocadherin beta 3","[PCDB3_HUMAN|Reviewed]RecName: Full=Protocadherin beta-3; Short=PCDH-beta-3; Flags: Precursor;+++[Q2M3R2_HUMAN|Unreviewed]SubName: Full=Protocadherin beta 3 {ECO:0000313|EMBL:AAI04818.1};"]
[56139,"'PCDHA10'",32.41,21.68,61.75,38.6133333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007399///nervous system development+++GO:0007155///cell adhesion","protocadherin alpha 10","[PCDAA_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-10; Short=PCDH-alpha-10; Flags: Precursor;"]
[5624,"'PROC'",8,9,24,13.6666666666667,"04610///Complement and coagulation cascades","H01723///Deep vein thrombosis (DVT)+++H00223///Inherited thrombophilia",null,null,"GO:0005881///cytoplasmic microtubule+++GO:0005794///Golgi apparatus+++GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0030877///beta-catenin destruction complex+++GO:0005788///endoplasmic reticulum lumen+++GO:0005923///bicellular tight junction+++GO:0005783///endoplasmic reticulum+++GO:0005913///cell-cell adherens junction+++GO:0016328///lateral plasma membrane+++GO:0016342///catenin complex+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0005576///extracellular region+++GO:0005912///adherens junction+++GO:0005634///nucleus+++GO:0042995///cell projection+++GO:0032587///ruffle membrane+++GO:0005796///Golgi lumen+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0005886///plasma membrane+++GO:0000776///kinetochore+++GO:1990909///Wnt signalosome+++GO:0005654///nucleoplasm+++GO:0005759///mitochondrial matrix","GO:0008233///peptidase activity+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016874///ligase activity+++GO:0005515///protein binding+++GO:0019887///protein kinase regulator activity+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding+++GO:0004736///pyruvate carboxylase activity+++GO:0005509///calcium ion binding+++GO:0000166///nucleotide binding+++GO:0019901///protein kinase binding+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0008013///beta-catenin binding+++GO:0008017///microtubule binding+++GO:0009374///biotin binding+++GO:0051010///microtubule plus-end binding+++GO:0045295///gamma-catenin binding+++GO:0008236///serine-type peptidase activity+++GO:0070840///dynein complex binding+++GO:0004252///serine-type endopeptidase activity","GO:0050819///negative regulation of coagulation+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0032886///regulation of microtubule-based process+++GO:0001708///cell fate specification+++GO:0043066///negative regulation of apoptotic process+++GO:0006629///lipid metabolic process+++GO:0000281///mitotic cytokinesis+++GO:0044267///cellular protein metabolic process+++GO:0045595///regulation of cell differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:1904886///beta-catenin destruction complex disassembly+++GO:1904885///beta-catenin destruction complex assembly+++GO:0007599///hemostasis+++GO:0050728///negative regulation of inflammatory response+++GO:0008152///metabolic process+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0030195///negative regulation of blood coagulation+++GO:0007389///pattern specification process+++GO:0006090///pyruvate metabolic process+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0044794///positive regulation by host of viral process+++GO:0065003///protein-containing complex assembly+++GO:0006094///gluconeogenesis+++GO:0051260///protein homooligomerization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0045732///positive regulation of protein catabolic process+++GO:0030335///positive regulation of cell migration+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007155///cell adhesion+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0008286///insulin receptor signaling pathway+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0010942///positive regulation of cell death+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:1904781///positive regulation of protein localization to centrosome+++GO:0016477///cell migration+++GO:0007596///blood coagulation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0016579///protein deubiquitination+++GO:0016055///Wnt signaling pathway+++GO:0006508///proteolysis+++GO:0019074///viral RNA genome packaging+++GO:0010629///negative regulation of gene expression+++GO:0006768///biotin metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0007050///cell cycle arrest+++GO:0043687///post-translational protein modification+++GO:0044791///positive regulation by host of viral release from host cell+++GO:0070830///bicellular tight junction assembly+++GO:0043065///positive regulation of apoptotic process","protein C, inactivator of coagulation factors Va and VIIIa","[PROC_HUMAN|Reviewed]RecName: Full=Vitamin K-dependent protein C; EC=3.4.21.69; AltName: Full=Anticoagulant protein C; AltName: Full=Autoprothrombin IIA; AltName: Full=Blood coagulation factor XIV; Contains: RecName: Full=Vitamin K-dependent protein C light chain; Contains: RecName: Full=Vitamin K-dependent protein C heavy chain; Contains: RecName: Full=Activation peptide; Flags: Precursor;+++[A0A087WYF3_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|Ensembl:ENSP00000481752};+++[A0A087X2F3_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|Ensembl:ENSP00000484935}; Flags: Fragment;+++[A0A1Y6IM53_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98737.1}; Flags: Fragment;+++[A0A1Y6IM71_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98744.1}; Flags: Fragment;+++[A0A1Y6IM94_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98760.1}; Flags: Fragment;+++[A0A1Y6IM95_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98756.1}; Flags: Fragment;+++[A0A1Y6IPP8_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98740.1}; Flags: Fragment;+++[A0A1Y6IQI2_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98742.1}; Flags: Fragment;+++[A0A1Y6IQK5_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98763.1}; Flags: Fragment;+++[A0A1Y6IRU6_HUMAN|Unreviewed]SubName: Full=Adenomatous Polyposis Coli {ECO:0000313|EMBL:SMR98764.1}; Flags: Fragment;+++[A0A224ANK2_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein isoform b {ECO:0000313|EMBL:BBA21111.1};+++[A0A224AV41_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein isoform t {ECO:0000313|EMBL:BBA21112.1}; SubName: Full=HCG2031476, isoform CRA_d {ECO:0000313|EMBL:EAW49005.1};+++[A0A2Q2SV78_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|Ensembl:ENSP00000423224}; Flags: Fragment;+++[A1YIQ7_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli {ECO:0000313|EMBL:ABL98125.1}; Flags: Fragment;+++[A1YIX6_HUMAN|Unreviewed]SubName: Full=Truncated adenomatous polyposis coli {ECO:0000313|EMBL:ABL98126.1}; Flags: Fragment;+++[A1YR11_HUMAN|Unreviewed]SubName: Full=Adenomatosis polyposis coli {ECO:0000313|EMBL:ABL85064.1}; Flags: Fragment;+++[A5HB94_HUMAN|Unreviewed]SubName: Full=Adenomatosis polyposis coli {ECO:0000313|EMBL:ABQ09219.1}; Flags: Fragment;+++[A5HB95_HUMAN|Unreviewed]SubName: Full=Adenomatosis polyposis coli {ECO:0000313|EMBL:ABQ09220.1}; Flags: Fragment;+++[A5HB96_HUMAN|Unreviewed]SubName: Full=Adenomatosis polyposis coli {ECO:0000313|EMBL:ABQ09217.1}; Flags: Fragment;+++[A5HB97_HUMAN|Unreviewed]SubName: Full=Adenomatosis polyposis coli {ECO:0000313|EMBL:ABQ09218.1}; Flags: Fragment;+++[A5JUM6_HUMAN|Unreviewed]SubName: Full=Truncated adenomatosis polyposis coli tumor suppressor {ECO:0000313|EMBL:ABQ57358.1}; Flags: Fragment;+++[A5JUM7_HUMAN|Unreviewed]SubName: Full=Truncated adenomatosis polyposis coli tumor suppressor {ECO:0000313|EMBL:ABQ57359.1}; Flags: Fragment;+++[A5JUM8_HUMAN|Unreviewed]SubName: Full=Adenomatosis polyposis coli tumor suppressor {ECO:0000313|EMBL:ABQ57360.1}; Flags: Fragment;+++[A5JUM9_HUMAN|Unreviewed]SubName: Full=Truncated adenomatosis polyposis coli tumor suppressor {ECO:0000313|EMBL:ABQ57361.1}; Flags: Fragment;+++[D6RFL6_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|Ensembl:ENSP00000426541}; Flags: Fragment;+++[E7EMH9_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|Ensembl:ENSP00000424265};+++[E7END6_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent protein C {ECO:0000313|Ensembl:ENSP00000386679};+++[E7ENR9_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent protein C {ECO:0000313|Ensembl:ENSP00000411241}; Flags: Fragment;+++[E7EU72_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent protein C {ECO:0000313|Ensembl:ENSP00000406295}; Flags: Fragment;+++[E7EVH6_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent protein C {ECO:0000313|Ensembl:ENSP00000412697}; Flags: Fragment;+++[E9PFT7_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|Ensembl:ENSP00000423828}; Flags: Fragment;+++[E9PRE7_HUMAN|Unreviewed]SubName: Full=Pyruvate carboxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000434192};+++[E9PS68_HUMAN|Unreviewed]SubName: Full=Pyruvate carboxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000435905};+++[F2Z2A0_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent protein C {ECO:0000313|Ensembl:ENSP00000392606};+++[H7BYX9_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent protein C {ECO:0000313|Ensembl:ENSP00000384225}; Flags: Fragment;+++[I7BL31_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:AFO53522.1}; EC=3.4.21.69 {ECO:0000313|EMBL:AFO53522.1}; Flags: Fragment;+++[L8E6S8_HUMAN|Unreviewed]SubName: Full=Alternative protein PC {ECO:0000313|EMBL:CCQ42945.1};+++[Q16097_HUMAN|Unreviewed]SubName: Full=APC protein {ECO:0000313|EMBL:AAD13997.1}; Flags: Fragment;+++[Q16098_HUMAN|Unreviewed]SubName: Full=APC protein {ECO:0000313|EMBL:AAD13999.1}; Flags: Fragment;+++[Q5EBR8_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|EMBL:AAX07546.1}; Flags: Fragment;+++[Q5EBR9_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|EMBL:AAX07544.1}; Flags: Fragment;+++[Q5EEK4_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposisi coli {ECO:0000313|EMBL:AAW82777.1}; Flags: Fragment;+++[Q7Z2Q8_HUMAN|Unreviewed]SubName: Full=APC protein {ECO:0000313|EMBL:AAH56268.1}; Flags: Fragment;+++[Q8IXB4_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC54280.1}; Flags: Fragment;+++[Q8IXB5_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC53631.1}; Flags: Fragment;+++[Q8IXB6_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC53630.1}; Flags: Fragment;+++[Q8IXB7_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC53629.1}; Flags: Fragment;+++[Q8J002_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21172.1}; Flags: Fragment;+++[Q8J003_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21171.1}; Flags: Fragment;+++[Q8J004_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21170.1}; Flags: Fragment;+++[Q8J005_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21169.1}; Flags: Fragment;+++[Q8J006_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21168.1}; Flags: Fragment;+++[Q8J007_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21167.1}; Flags: Fragment;+++[Q8J008_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21166.1}; Flags: Fragment;+++[Q8J009_HUMAN|Unreviewed]SubName: Full=Protein C {ECO:0000313|EMBL:BAC21165.1}; Flags: Fragment;+++[Q9HAW6_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|EMBL:AAG25599.1}; Flags: Fragment;+++[Q9P119_HUMAN|Unreviewed]SubName: Full=Adenomatosis polyposis coli tumor suppressor {ECO:0000313|EMBL:AAF34355.1}; Flags: Fragment;+++[Q9UM98_HUMAN|Unreviewed]SubName: Full=APC protein {ECO:0000313|EMBL:AAD13998.1}; Flags: Fragment;+++[R4GMU6_HUMAN|Unreviewed]SubName: Full=Adenomatous polyposis coli protein {ECO:0000313|Ensembl:ENSP00000473355}; Flags: Fragment;"]
[56267,"'KYAT3'",147.99,132.01,150.06,143.353333333333,"00450///Selenocompound metabolism+++05204///Chemical carcinogenesis+++00380///Tryptophan metabolism+++01100///Metabolic pathways",null,null,"R09366///Se-methyl-L-selenocysteine methaneselenol-lyase (deaminating; pyruvate-forming)   Se-Methyl-L-selenocysteine + H2O <=> Pyruvate + Ammonia + Methaneselenol+++R04171///3-Hydroxy-L-kynurenine:2-oxoglutarate aminotransferase   3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate+++R09373///L-methionine:methylselenopyruvate aminotransferase   Se-Methyl-L-selenocysteine + 4-Methylthio-2-oxobutanoic acid <=> Methylselenopyruvate + L-Methionine+++R01956///L-Kynurenine:2-oxoglutarate aminotransferase   L-Kynurenine + 2-Oxoglutarate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + L-Glutamate","GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0036137///kynurenine aminotransferase activity+++GO:0047804///cysteine-S-conjugate beta-lyase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0016212///kynurenine-oxoglutarate transaminase activity+++GO:0042803///protein homodimerization activity+++GO:0016740///transferase activity+++GO:0047315///kynurenine-glyoxylate transaminase activity+++GO:0008483///transaminase activity","GO:0009058///biosynthetic process+++GO:0070189///kynurenine metabolic process+++GO:0097052///L-kynurenine metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006520///cellular amino acid metabolic process","kynurenine aminotransferase 3","[KAT3_HUMAN|Reviewed]RecName: Full=Kynurenine--oxoglutarate transaminase 3; EC=2.6.1.7; AltName: Full=Cysteine-S-conjugate beta-lyase 2; EC=4.4.1.13; AltName: Full=Kynurenine aminotransferase 3 {ECO:0000312|HGNC:HGNC:33238}; AltName: Full=Kynurenine aminotransferase III; Short=KATIII; AltName: Full=Kynurenine--glyoxylate transaminase; EC=2.6.1.63; AltName: Full=Kynurenine--oxoglutarate transaminase III;+++[A0A0A0MRN7_HUMAN|Unreviewed]SubName: Full=Kynurenine--oxoglutarate transaminase 3 {ECO:0000313|Ensembl:ENSP00000359517}; Flags: Fragment;+++[B4DW13_HUMAN|Unreviewed]SubName: Full=HCG23341, isoform CRA_d {ECO:0000313|EMBL:EAW73158.1}; SubName: Full=cDNA FLJ56161, highly similar to Homo sapiens kynurenine aminotransferase III (KAT3), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62875.1}; SubName: Full=cDNA, FLJ78816, highly similar to Homo sapiens kynurenine aminotransferase III (KAT3), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH14288.1};+++[L0R594_HUMAN|Unreviewed]SubName: Full=Alternative protein CCBL2 {ECO:0000313|EMBL:CCO13699.1};"]
[56301,"'SLC7A10'",28,19,16,21,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity","GO:0050900///leukocyte migration+++GO:0015804///neutral amino acid transport+++GO:0055085///transmembrane transport+++GO:0042942///D-serine transport+++GO:0006865///amino acid transport+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:0015825///L-serine transport+++GO:0042941///D-alanine transport","solute carrier family 7 member 10","[AAA1_HUMAN|Reviewed]RecName: Full=Asc-type amino acid transporter 1; Short=Asc-1; AltName: Full=Solute carrier family 7 member 10;+++[K7EK24_HUMAN|Unreviewed]SubName: Full=Asc-type amino acid transporter 1 {ECO:0000313|Ensembl:ENSP00000465421};+++[K7ENB6_HUMAN|Unreviewed]SubName: Full=Asc-type amino acid transporter 1 {ECO:0000313|Ensembl:ENSP00000466876};"]
[5651,"'TMPRSS15'",1,0,1,0.666666666666667,null,"H00988///Enterokinase deficiency",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005903///brush border","GO:0016787///hydrolase activity+++GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0008236///serine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0004252///serine-type endopeptidase activity","GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis","transmembrane serine protease 15","[ENTK_HUMAN|Reviewed]RecName: Full=Enteropeptidase; EC=3.4.21.9; AltName: Full=Enterokinase; AltName: Full=Serine protease 7; AltName: Full=Transmembrane protease serine 15; Contains: RecName: Full=Enteropeptidase non-catalytic heavy chain; Contains: RecName: Full=Enteropeptidase catalytic light chain; Flags: Precursor;+++[E9PG70_HUMAN|Unreviewed]SubName: Full=Enteropeptidase {ECO:0000313|Ensembl:ENSP00000398253}; Flags: Fragment;+++[Q9NR95_HUMAN|Unreviewed]SubName: Full=Enteropeptidase {ECO:0000313|EMBL:AAF97778.1}; EC=3.4.21.9 {ECO:0000313|EMBL:AAF97778.1}; Flags: Fragment;"]
[56605,"'ERO1B'",77,61,69,69,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0005515///protein binding+++GO:0051082///unfolded protein binding+++GO:0003756///protein disulfide isomerase activity+++GO:0016491///oxidoreductase activity","GO:0034975///protein folding in endoplasmic reticulum+++GO:0030198///extracellular matrix organization+++GO:0019471///4-hydroxyproline metabolic process+++GO:0055114///oxidation-reduction process+++GO:0045454///cell redox homeostasis+++GO:0006457///protein folding+++GO:0022417///protein maturation by protein folding+++GO:0042593///glucose homeostasis+++GO:0030070///insulin processing","endoplasmic reticulum oxidoreductase 1 beta","[ERO1B_HUMAN|Reviewed]RecName: Full=ERO1-like protein beta; Short=ERO1-L-beta; EC=1.8.4.-; AltName: Full=Endoplasmic reticulum oxidoreductase beta {ECO:0000312|HGNC:HGNC:14355}; AltName: Full=Endoplasmic reticulum oxidoreductin-1-like protein B; AltName: Full=Oxidoreductin-1-L-beta; Flags: Precursor;+++[Q5T1H5_HUMAN|Unreviewed]SubName: Full=ERO1-like protein beta {ECO:0000313|Ensembl:ENSP00000355548}; Flags: Fragment;+++[Q5TAE8_HUMAN|Unreviewed]SubName: Full=ERO1-like protein beta {ECO:0000313|Ensembl:ENSP00000264181}; Flags: Fragment;"]
[56675,"'NRIP3'",64.87,46,49.43,53.4333333333333,{"$nulls":5},"GO:0005515///protein binding+++GO:0004190///aspartic-type endopeptidase activity","GO:0006508///proteolysis","nuclear receptor interacting protein 3","[NRIP3_HUMAN|Reviewed]RecName: Full=Nuclear receptor-interacting protein 3; AltName: Full=Sarcoma antigen NY-SAR-105;+++[B7Z3Y4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51629, highly similar to Nuclear receptor-interacting protein 3 {ECO:0000313|EMBL:BAH12370.1};+++[E9PIW3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000433845}; Flags: Fragment;+++[H0YCM9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000432002}; Flags: Fragment;+++[H0YEG7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000435785}; Flags: Fragment;"]
[56681,"'SAR1A'",1529,1261,1302,1364,"04141///Protein processing in endoplasmic reticulum+++05134///Legionellosis","H00927///Chylomicron retention disease (CRD)","M00404///COPII complex",null,"GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0070971///endoplasmic reticulum exit site+++GO:0005623///cell+++GO:0030127///COPII vesicle coat+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding","GO:0003400///regulation of COPII vesicle coating+++GO:0061024///membrane organization+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0016050///vesicle organization","secretion associated Ras related GTPase 1A","[SAR1A_HUMAN|Reviewed]RecName: Full=GTP-binding protein SAR1a; AltName: Full=COPII-associated small GTPase;+++[H0Y5E8_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1a {ECO:0000313|Ensembl:ENSP00000398165}; Flags: Fragment;+++[Q5SQT8_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1a {ECO:0000313|Ensembl:ENSP00000362333};+++[Q5SQT9_HUMAN|Unreviewed]SubName: Full=SAR1 gene homolog A (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW54378.1}; SubName: Full=Small GTP-binding protein {ECO:0000313|EMBL:AAL27183.1};+++[Q6FID4_HUMAN|Unreviewed]SubName: Full=SARA1 protein {ECO:0000313|EMBL:CAG38523.1};+++[X1WI22_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1a {ECO:0000313|Ensembl:ENSP00000362336}; Flags: Fragment;"]
[5688,"'PSMA7'",1196,1011,1071,1092.66666666667,"03050///Proteasome",null,"M00340///Proteasome, 20S core particle+++M00337///Immunoproteasome",null,"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0098794///postsynapse+++GO:0000502///proteasome complex+++GO:0005839///proteasome core complex+++GO:0005579///membrane attack complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0019773///proteasome core complex, alpha-subunit complex","GO:0004298///threonine-type endopeptidase activity+++GO:0042802///identical protein binding+++GO:0004175///endopeptidase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0006508///proteolysis+++GO:0016032///viral process+++GO:0006956///complement activation+++GO:0030449///regulation of complement activation+++GO:0001970///positive regulation of activation of membrane attack complex+++GO:0019835///cytolysis+++GO:0045766///positive regulation of angiogenesis+++GO:0006955///immune response+++GO:0043687///post-translational protein modification+++GO:0006958///complement activation, classical pathway+++GO:0016579///protein deubiquitination+++GO:0045917///positive regulation of complement activation+++GO:0001701///in utero embryonic development+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0010498///proteasomal protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process","proteasome subunit alpha 7","[PSA7_HUMAN|Reviewed]RecName: Full=Proteasome subunit alpha type-7; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=Proteasome subunit RC6-1; AltName: Full=Proteasome subunit XAPC7;+++[A0A0K0K1K4_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[C9JC72_HUMAN|Unreviewed]SubName: Full=Complement component C6 {ECO:0000313|Ensembl:ENSP00000396565}; Flags: Fragment;+++[C9JX36_HUMAN|Unreviewed]SubName: Full=Complement component C6 {ECO:0000313|Ensembl:ENSP00000401578}; Flags: Fragment;+++[H0Y586_HUMAN|Unreviewed]RecName: Full=Proteasome endopeptidase complex {ECO:0000256|PROSITE-ProRule:PRU00808}; EC=3.4.25.1 {ECO:0000256|PROSITE-ProRule:PRU00808}; Flags: Fragment;+++[Q05DH1_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551}; Flags: Fragment;"]
[56888,"'KCMF1'",789,666.99,607,687.663333333333,{"$nulls":4},"GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005829///cytosol","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity","GO:0043312///neutrophil degranulation+++GO:0016567///protein ubiquitination","potassium channel modulatory factor 1","[KCMF1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase KCMF1; EC=2.3.2.27; AltName: Full=FGF-induced in gastric cancer; AltName: Full=Potassium channel modulatory factor; Short=PCMF; AltName: Full=RING-type E3 ubiquitin transferase KCMF1 {ECO:0000305}; AltName: Full=ZZ-type zinc finger-containing protein 1;+++[A0A1D5RMQ3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase KCMF1 {ECO:0000313|Ensembl:ENSP00000414214}; Flags: Fragment;+++[C9J3I2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase KCMF1 {ECO:0000313|Ensembl:ENSP00000391340}; Flags: Fragment;+++[C9JSW5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase KCMF1 {ECO:0000313|Ensembl:ENSP00000409499}; Flags: Fragment;"]
[56918,"'C2orf83'",0,0,1,0.333333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0015234///thiamine transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0071934///thiamine transmembrane transport+++GO:0035461///vitamin transmembrane transport+++GO:0051180///vitamin transport","chromosome 2 open reading frame 83","[CB083_HUMAN|Reviewed]RecName: Full=Folate transporter-like protein C2orf83;"]
[56920,"'SEMA3G'",4,7,4,5,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane","GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0005102///signaling receptor binding+++GO:0045499///chemorepellent activity","GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0030517///negative regulation of axon extension","semaphorin 3G","[SEM3G_HUMAN|Reviewed]RecName: Full=Semaphorin-3G; AltName: Full=Semaphorin sem2; Flags: Precursor;+++[C9JXB2_HUMAN|Unreviewed]SubName: Full=Semaphorin-3G {ECO:0000313|Ensembl:ENSP00000419181}; Flags: Fragment;+++[H7C5M7_HUMAN|Unreviewed]SubName: Full=Semaphorin-3G {ECO:0000313|Ensembl:ENSP00000420291}; Flags: Fragment;"]
[56941,"'HMCES'",331,310,280,307,{"$nulls":5},"GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0003677///DNA binding+++GO:0003674///molecular_function","GO:0006508///proteolysis+++GO:0008150///biological_process","5-hydroxymethylcytosine binding, ES cell specific","[HMCES_HUMAN|Reviewed]RecName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein; Short=ES cell-specific 5hmC-binding protein; AltName: Full=Putative peptidase SRAPD1; EC=3.4.-.-; AltName: Full=SRAP domain-containing protein 1;+++[D6R9T3_HUMAN|Unreviewed]RecName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein {ECO:0000256|RuleBase:RU364100}; Short=ES cell-specific 5hmC-binding protein {ECO:0000256|RuleBase:RU364100}; EC=3.4.-.- {ECO:0000256|RuleBase:RU364100}; AltName: Full=Putative peptidase SRAPD1 {ECO:0000256|RuleBase:RU364100}; AltName: Full=SRAP domain-containing protein 1 {ECO:0000256|RuleBase:RU364100}; Flags: Fragment;+++[D6RAI0_HUMAN|Unreviewed]RecName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein {ECO:0000256|RuleBase:RU364100}; Short=ES cell-specific 5hmC-binding protein {ECO:0000256|RuleBase:RU364100}; EC=3.4.-.- {ECO:0000256|RuleBase:RU364100}; AltName: Full=Putative peptidase SRAPD1 {ECO:0000256|RuleBase:RU364100}; AltName: Full=SRAP domain-containing protein 1 {ECO:0000256|RuleBase:RU364100}; Flags: Fragment;+++[D6RAZ3_HUMAN|Unreviewed]RecName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein {ECO:0000256|RuleBase:RU364100}; Short=ES cell-specific 5hmC-binding protein {ECO:0000256|RuleBase:RU364100}; EC=3.4.-.- {ECO:0000256|RuleBase:RU364100}; AltName: Full=Putative peptidase SRAPD1 {ECO:0000256|RuleBase:RU364100}; AltName: Full=SRAP domain-containing protein 1 {ECO:0000256|RuleBase:RU364100}; Flags: Fragment;+++[D6RGK7_HUMAN|Unreviewed]RecName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein {ECO:0000256|RuleBase:RU364100}; Short=ES cell-specific 5hmC-binding protein {ECO:0000256|RuleBase:RU364100}; EC=3.4.-.- {ECO:0000256|RuleBase:RU364100}; AltName: Full=Putative peptidase SRAPD1 {ECO:0000256|RuleBase:RU364100}; AltName: Full=SRAP domain-containing protein 1 {ECO:0000256|RuleBase:RU364100}; Flags: Fragment;+++[E7EMP6_HUMAN|Unreviewed]RecName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein {ECO:0000256|RuleBase:RU364100}; Short=ES cell-specific 5hmC-binding protein {ECO:0000256|RuleBase:RU364100}; EC=3.4.-.- {ECO:0000256|RuleBase:RU364100}; AltName: Full=Putative peptidase SRAPD1 {ECO:0000256|RuleBase:RU364100}; AltName: Full=SRAP domain-containing protein 1 {ECO:0000256|RuleBase:RU364100};"]
[56954,"'NIT2'",180,156,183,173,"00250///Alanine, aspartate and glutamate metabolism",null,null,"R00269///2-oxoglutaramate amidohydrolase   2-Oxoglutaramate + H2O <=> 2-Oxoglutarate + Ammonia+++R00348///2-oxosuccinamate amidohydrolase   2-Oxosuccinamate + H2O <=> Oxaloacetate + Ammonia","GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:1904724///tertiary granule lumen+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0035580///specific granule lumen","GO:0016787///hydrolase activity+++GO:0050152///omega-amidase activity","GO:0006541///glutamine metabolic process+++GO:0006107///oxaloacetate metabolic process+++GO:0006528///asparagine metabolic process+++GO:0043312///neutrophil degranulation+++GO:0006807///nitrogen compound metabolic process","nitrilase family member 2","[NIT2_HUMAN|Reviewed]RecName: Full=Omega-amidase NIT2; EC=3.5.1.3; AltName: Full=Nitrilase homolog 2;+++[F8WF58_HUMAN|Unreviewed]SubName: Full=Omega-amidase NIT2 {ECO:0000313|Ensembl:ENSP00000419239};+++[F8WF70_HUMAN|Unreviewed]SubName: Full=Omega-amidase NIT2 {ECO:0000313|Ensembl:ENSP00000419157};+++[H7C579_HUMAN|Unreviewed]SubName: Full=Omega-amidase NIT2 {ECO:0000313|Ensembl:ENSP00000419189}; Flags: Fragment;+++[V9HW91_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 8a {ECO:0000313|EMBL:ACI46018.1};"]
[56983,"'POGLUT1'",291,266,239,265.333333333333,"00514///Other types of O-glycan biosynthesis","H00593///Limb-girdle muscular dystrophy (LGMD)",null,"R09315///UDP-D-glucose + [Protein]-L-serine <=> UDP + G13051","GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0030158///protein xylosyltransferase activity+++GO:0046527///glucosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0035251///UDP-glucosyltransferase activity+++GO:0035252///UDP-xylosyltransferase activity","GO:0007369///gastrulation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0006493///protein O-linked glycosylation+++GO:0010470///regulation of gastrulation+++GO:0007275///multicellular organism development+++GO:0048318///axial mesoderm development+++GO:0006486///protein glycosylation+++GO:0008593///regulation of Notch signaling pathway+++GO:0001756///somitogenesis+++GO:0060537///muscle tissue development+++GO:0048339///paraxial mesoderm development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0072358///cardiovascular system development","protein O-glucosyltransferase 1","[PGLT1_HUMAN|Reviewed]RecName: Full=Protein O-glucosyltransferase 1 {ECO:0000305}; EC=2.4.1.- {ECO:0000269|PubMed:21490058, ECO:0000269|PubMed:21949356}; AltName: Full=CAP10-like 46 kDa protein {ECO:0000303|PubMed:16524674}; Short=hCLP46 {ECO:0000303|PubMed:16524674}; AltName: Full=KTEL motif-containing protein 1; AltName: Full=Myelodysplastic syndromes relative protein; AltName: Full=O-glucosyltransferase Rumi homolog {ECO:0000303|PubMed:21490058}; Short=hRumi {ECO:0000303|PubMed:21490058}; AltName: Full=Protein O-xylosyltransferase POGLUT1 {ECO:0000305}; EC=2.4.2.26 {ECO:0000269|PubMed:21081508, ECO:0000269|PubMed:28775322}; Flags: Precursor;+++[B4DJ97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53005, highly similar to CAP10-like 46 kDa protein {ECO:0000313|EMBL:BAG58759.1};+++[B4DVA9_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419288}; SubName: Full=cDNA FLJ53000, highly similar to CAP10-like 46 kDa protein {ECO:0000313|EMBL:BAG62621.1};+++[F8WDC4_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000420594};+++[F8WEW4_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419876};+++[H7C5H0_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419865}; Flags: Fragment;"]
[5700,"'PSMC1'",1012,1064,951,1009,"03050///Proteasome+++05169///Epstein-Barr virus infection+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0005838///proteasome regulatory particle+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0022624///proteasome accessory complex","GO:0003723///RNA binding+++GO:0036402///proteasome-activating ATPase activity+++GO:0016787///hydrolase activity+++GO:0016887///ATPase activity+++GO:0005524///ATP binding+++GO:0017025///TBP-class protein binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:1901215///negative regulation of neuron death+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0006457///protein folding+++GO:0043687///post-translational protein modification+++GO:0030163///protein catabolic process+++GO:0016579///protein deubiquitination","proteasome 26S subunit, ATPase 1","[PRS4_HUMAN|Reviewed]RecName: Full=26S proteasome regulatory subunit 4; Short=P26s4; AltName: Full=26S proteasome AAA-ATPase subunit RPT2; AltName: Full=Proteasome 26S subunit ATPase 1;+++[G3V4X1_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 4 {ECO:0000313|Ensembl:ENSP00000452049}; Flags: Fragment;+++[Q53XL8_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) 26S subunit, ATPase, 1 {ECO:0000313|EMBL:AAP88828.1}; SubName: Full=Proteasome (Prosome, macropain) 26S subunit, ATPase, 1, isoform CRA_a {ECO:0000313|EMBL:EAW81419.1}; SubName: Full=Proteasome 26S ATPase subunit 1 {ECO:0000313|EMBL:BAG70125.1}; SubName: Full=cDNA, FLJ93843, Homo sapiens proteasome (prosome, macropain) 26S subunit, ATPase, 1(PSMC1), mRNA {ECO:0000313|EMBL:BAG36130.1};"]
[57037,"'ANKMY2'",225,246,228,233,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005929///cilium+++GO:0042995///cell projection","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding","GO:0008589///regulation of smoothened signaling pathway","ankyrin repeat and MYND domain containing 2","[ANKY2_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and MYND domain-containing protein 2;+++[A0A024R9Z6_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and MYND domain containing 2, isoform CRA_b {ECO:0000313|EMBL:EAW93673.1};+++[F8WB95_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and MYND domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000410075};+++[G3V0G5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and MYND domain containing 2, isoform CRA_c {ECO:0000313|EMBL:EAW93674.1}; SubName: Full=Ankyrin repeat and MYND domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000392259};"]
[57085,"'AGTRAP'",1132,1049,1067,1082.66666666667,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005938///cell cortex","GO:0004945///angiotensin type II receptor activity+++GO:0005515///protein binding","GO:0038166///angiotensin-activated signaling pathway+++GO:0001666///response to hypoxia+++GO:0008217///regulation of blood pressure","angiotensin II receptor associated protein","[ATRAP_HUMAN|Reviewed]RecName: Full=Type-1 angiotensin II receptor-associated protein; AltName: Full=AT1 receptor-associated protein;+++[D6RB40_HUMAN|Unreviewed]SubName: Full=Type-1 angiotensin II receptor-associated protein {ECO:0000313|Ensembl:ENSP00000424455};+++[D6RBK6_HUMAN|Unreviewed]SubName: Full=Type-1 angiotensin II receptor-associated protein {ECO:0000313|Ensembl:ENSP00000422647};+++[X6R9H3_HUMAN|Unreviewed]SubName: Full=Type-1 angiotensin II receptor-associated protein {ECO:0000313|Ensembl:ENSP00000365814};"]
[57106,"'NAT14'",609,530,504,547.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016746///transferase activity, transferring acyl groups+++GO:0003677///DNA binding+++GO:0016740///transferase activity","GO:0006352///DNA-templated transcription, initiation+++GO:0045893///positive regulation of transcription, DNA-templated","N-acetyltransferase 14 (putative)","[NAT14_HUMAN|Reviewed]RecName: Full=N-acetyltransferase 14; EC=2.3.1.-; AltName: Full=K562 cell-derived leucine-zipper-like protein 1;+++[M0QZH3_HUMAN|Unreviewed]SubName: Full=N-acetyltransferase 14 {ECO:0000313|Ensembl:ENSP00000470543};+++[M0R1E3_HUMAN|Unreviewed]SubName: Full=N-acetyltransferase 14 {ECO:0000313|Ensembl:ENSP00000471807}; Flags: Fragment;+++[M0R284_HUMAN|Unreviewed]SubName: Full=N-acetyltransferase 14 {ECO:0000313|Ensembl:ENSP00000472383};"]
[57126,"'CD177'",415,328,324,355.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane+++GO:0030027///lamellipodium+++GO:0044853///plasma membrane raft+++GO:0031225///anchored component of membrane+++GO:0042995///cell projection+++GO:0005576///extracellular region+++GO:0030667///secretory granule membrane+++GO:0045121///membrane raft+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0002020///protease binding+++GO:0048306///calcium-dependent protein binding","GO:0007596///blood coagulation+++GO:0034394///protein localization to cell surface+++GO:0043312///neutrophil degranulation+++GO:0045217///cell-cell junction maintenance+++GO:0007159///leukocyte cell-cell adhesion+++GO:0072672///neutrophil extravasation+++GO:0032930///positive regulation of superoxide anion generation+++GO:0045087///innate immune response+++GO:0050900///leukocyte migration+++GO:0030100///regulation of endocytosis+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0043315///positive regulation of neutrophil degranulation+++GO:1990266///neutrophil migration+++GO:0002376///immune system process+++GO:2001044///regulation of integrin-mediated signaling pathway","CD177 molecule","[CD177_HUMAN|Reviewed]RecName: Full=CD177 antigen {ECO:0000312|HGNC:HGNC:30072}; AltName: Full=Human neutrophil alloantigen 2a {ECO:0000305|PubMed:11465086}; Short=HNA-2a {ECO:0000305|PubMed:11465086}; AltName: Full=NB1 glycoprotein {ECO:0000305|PubMed:11465086}; Short=NB1 GP {ECO:0000305|PubMed:11465086}; AltName: Full=Polycythemia rubra vera protein 1 {ECO:0000303|PubMed:10753836}; Short=PRV-1 {ECO:0000303|PubMed:10753836}; AltName: CD_antigen=CD177; Flags: Precursor;+++[A0A087WVM2_HUMAN|Unreviewed]SubName: Full=CD177 antigen {ECO:0000313|Ensembl:ENSP00000479536};+++[A0A087X113_HUMAN|Unreviewed]SubName: Full=CD177 antigen {ECO:0000313|Ensembl:ENSP00000483817};+++[D2N288_HUMAN|Unreviewed]SubName: Full=Putative CD177 protein {ECO:0000313|EMBL:CAP05216.1};+++[Q1T7A3_HUMAN|Unreviewed]SubName: Full=CD177 {ECO:0000313|EMBL:BAE93254.1};"]
[57150,"'SMIM8'",26,35,47,36,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"small integral membrane protein 8","[SMIM8_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 8;+++[V9GYF9_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 8 {ECO:0000313|Ensembl:ENSP00000476709};+++[V9GYL2_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 8 {ECO:0000313|Ensembl:ENSP00000476881};"]
[57169,"'ZNFX1'",1251.97,1184,1158,1197.99,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0031380///nuclear RNA-directed RNA polymerase complex+++GO:0000775///chromosome, centromeric region","GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008270///zinc ion binding+++GO:0003723///RNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0030702///chromatin silencing at centromere+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031048///chromatin silencing by small RNA","zinc finger NFX1-type containing 1","[ZNFX1_HUMAN|Reviewed]RecName: Full=NFX1-type zinc finger-containing protein 1;+++[H0UI63_HUMAN|Unreviewed]SubName: Full=Zinc finger, NFX1-type containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW75663.1};+++[Q2TAK0_HUMAN|Unreviewed]SubName: Full=ZNFX1 protein {ECO:0000313|EMBL:AAI10889.1};+++[Q5JXR5_HUMAN|Unreviewed]SubName: Full=NFX1-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000360809}; Flags: Fragment;+++[Q5JXR6_HUMAN|Unreviewed]SubName: Full=NFX1-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000360819};+++[Q5JXR7_HUMAN|Unreviewed]SubName: Full=NFX1-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000413800}; Flags: Fragment;+++[Q6P6B6_HUMAN|Unreviewed]SubName: Full=ZNFX1 protein {ECO:0000313|EMBL:AAH62347.1}; Flags: Fragment;+++[Q6PJM4_HUMAN|Unreviewed]SubName: Full=ZNFX1 protein {ECO:0000313|EMBL:AAH14041.1}; Flags: Fragment;"]
[57188,"'ADAMTSL3'",1630,2259,1785,1891.33333333333,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0008233///peptidase activity","GO:0006508///proteolysis","ADAMTS like 3","[ATL3_HUMAN|Reviewed]RecName: Full=ADAMTS-like protein 3; Short=ADAMTSL-3; AltName: Full=Punctin-2; Flags: Precursor;"]
[57222,"'ERGIC1'",4815,4560,4209,4528,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005654///nucleoplasm+++GO:0000139///Golgi membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER","endoplasmic reticulum-golgi intermediate compartment 1","[ERGI1_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 1; AltName: Full=ER-Golgi intermediate compartment 32 kDa protein; Short=ERGIC-32;+++[A0A1B0GTQ3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 1 {ECO:0000313|Ensembl:ENSP00000489795};+++[F2Z2P5_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 1 {ECO:0000313|Ensembl:ENSP00000428064};+++[F2Z2U2_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 1 {ECO:0000313|Ensembl:ENSP00000427713};+++[F2Z3Q5_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 1 {ECO:0000313|Ensembl:ENSP00000429501}; Flags: Fragment;+++[H0YAV2_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 1 {ECO:0000313|Ensembl:ENSP00000428116}; Flags: Fragment;"]
[5728,"'PTEN'",1869,1947,1743,1853,"01521///EGFR tyrosine kinase inhibitor resistance+++05218///Melanoma+++05224///Breast cancer+++04218///Cellular senescence+++05213///Endometrial cancer+++04071///Sphingolipid signaling pathway+++05206///MicroRNAs in cancer+++05215///Prostate cancer+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05214///Glioma+++05225///Hepatocellular carcinoma+++05230///Central carbon metabolism in cancer+++05165///Human papillomavirus infection+++00562///Inositol phosphate metabolism+++04151///PI3K-Akt signaling pathway+++04068///FoxO signaling pathway+++05161///Hepatitis B+++04070///Phosphatidylinositol signaling system+++04510///Focal adhesion+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++05222///Small cell lung cancer+++04115///p53 signaling pathway+++04931///Insulin resistance","H00013///Small cell lung cancer+++H01556///Meningioma+++H00539///PTEN hamartoma tumor syndrome (PHTS)+++H00042///Glioma+++H00048///Hepatocellular carcinoma+++H01195///VACTERL/VATER association+++H00031///Breast cancer+++H01463///Mycosis fungoides+++H01222///Cowden syndrome+++H00038///Melanoma+++H00024///Prostate cancer+++H00026///Endometrial cancer+++H00029///Vulvar cancer",null,"R03363///1-Phosphatidyl-1D-myo-inositol 3-phosphate 3-phosphohydrolase   1-Phosphatidyl-1D-myo-inositol 3-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate+++R04513///Phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase   Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + Orthophosphate","GO:0005634///nucleus+++GO:0099524///postsynaptic cytosol+++GO:0016605///PML body+++GO:0005576///extracellular region+++GO:0042995///cell projection+++GO:0035749///myelin sheath adaxonal region+++GO:1990904///ribonucleoprotein complex+++GO:0043197///dendritic spine+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005654///nucleoplasm+++GO:0016324///apical plasma membrane+++GO:0005694///chromosome+++GO:0043220///Schmidt-Lanterman incisure+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0000781///chromosome, telomeric region","GO:0042802///identical protein binding+++GO:0003723///RNA binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0016314///phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0002039///p53 binding+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0070034///telomerase RNA binding+++GO:0005524///ATP binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:1990782///protein tyrosine kinase binding+++GO:0051800///phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity+++GO:0003720///telomerase activity+++GO:0010997///anaphase-promoting complex binding+++GO:0019901///protein kinase binding+++GO:0008289///lipid binding+++GO:0051717///inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0030165///PDZ domain binding+++GO:0019899///enzyme binding+++GO:0004721///phosphoprotein phosphatase activity","GO:0046621///negative regulation of organ growth+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0030534///adult behavior+++GO:0033555///multicellular organismal response to stress+++GO:0006470///protein dephosphorylation+++GO:0045666///positive regulation of neuron differentiation+++GO:0060024///rhythmic synaptic transmission+++GO:0090071///negative regulation of ribosome biogenesis+++GO:0045471///response to ethanol+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0071257///cellular response to electrical stimulus+++GO:0048681///negative regulation of axon regeneration+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:0014070///response to organic cyclic compound+++GO:0021955///central nervous system neuron axonogenesis+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0071456///cellular response to hypoxia+++GO:0032869///cellular response to insulin stimulus+++GO:0051726///regulation of cell cycle+++GO:0016579///protein deubiquitination+++GO:0016477///cell migration+++GO:0060070///canonical Wnt signaling pathway+++GO:0050765///negative regulation of phagocytosis+++GO:0043491///protein kinase B signaling+++GO:0043065///positive regulation of apoptotic process+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0007626///locomotory behavior+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0046855///inositol phosphate dephosphorylation+++GO:0007270///neuron-neuron synaptic transmission+++GO:1903984///positive regulation of TRAIL-activated apoptotic signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0046685///response to arsenic-containing substance+++GO:0042493///response to drug+++GO:0007568///aging+++GO:0048854///brain morphogenesis+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0044320///cellular response to leptin stimulus+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0006915///apoptotic process+++GO:2000272///negative regulation of signaling receptor activity+++GO:0014823///response to activity+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:0016311///dephosphorylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0001525///angiogenesis+++GO:0045792///negative regulation of cell size+++GO:0030336///negative regulation of cell migration+++GO:0060074///synapse maturation+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0048738///cardiac muscle tissue development+++GO:0032535///regulation of cellular component size+++GO:0035176///social behavior+++GO:0060291///long-term synaptic potentiation+++GO:0060134///prepulse inhibition+++GO:0032355///response to estradiol+++GO:0060179///male mating behavior+++GO:0010033///response to organic substance+++GO:0043542///endothelial cell migration+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0007584///response to nutrient+++GO:0050771///negative regulation of axonogenesis+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000808///negative regulation of synaptic vesicle clustering+++GO:0060292///long-term synaptic depression+++GO:0010975///regulation of neuron projection development+++GO:0002902///regulation of B cell apoptotic process+++GO:0097105///presynaptic membrane assembly+++GO:0021542///dentate gyrus development+++GO:0071361///cellular response to ethanol+++GO:0031175///neuron projection development+++GO:0031642///negative regulation of myelination+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0036294///cellular response to decreased oxygen levels+++GO:0031647///regulation of protein stability+++GO:0032286///central nervous system myelin maintenance+++GO:0007611///learning or memory+++GO:0060736///prostate gland growth+++GO:0007399///nervous system development+++GO:0007613///memory+++GO:0000722///telomere maintenance via recombination+++GO:0042711///maternal behavior+++GO:0006629///lipid metabolic process+++GO:0097107///postsynaptic density assembly+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:0050821///protein stabilization+++GO:0010628///positive regulation of gene expression+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0090344///negative regulation of cell aging+++GO:0060341///regulation of cellular localization+++GO:0008285///negative regulation of cell proliferation+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0008283///cell proliferation+++GO:0051548///negative regulation of keratinocyte migration+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010043///response to zinc ion+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0045475///locomotor rhythm+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0007417///central nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0007507///heart development+++GO:0060997///dendritic spine morphogenesis+++GO:0048679///regulation of axon regeneration+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0007416///synapse assembly+++GO:0033032///regulation of myeloid cell apoptotic process+++GO:1903690///negative regulation of wound healing, spreading of epidermal cells+++GO:0048853///forebrain morphogenesis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043647///inositol phosphate metabolic process+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0010035///response to inorganic substance+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0033198///response to ATP","phosphatase and tensin homolog","[PTEN_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; EC=3.1.3.16 {ECO:0000269|PubMed:9256433}; EC=3.1.3.48 {ECO:0000269|PubMed:9187108, ECO:0000269|PubMed:9256433}; EC=3.1.3.67 {ECO:0000269|PubMed:9593664, ECO:0000269|PubMed:9811831}; AltName: Full=Mutated in multiple advanced cancers 1; AltName: Full=Phosphatase and tensin homolog;+++[A0A024QYR6_HUMAN|Unreviewed]SubName: Full=Mitochondrial PTENalpha {ECO:0000313|EMBL:DAA64601.1};+++[A0A087X033_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN {ECO:0000313|Ensembl:ENSP00000483066}; Flags: Fragment;+++[A0A142FGX1_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein {ECO:0000313|EMBL:AMQ76357.1}; Flags: Fragment;+++[A0A1V0DNR7_HUMAN|Unreviewed]SubName: Full=PTENbeta {ECO:0000313|EMBL:ARB02560.1}; EC=3.1.3.67 {ECO:0000313|EMBL:ARB02560.1};+++[A0A2P0XNP6_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase {ECO:0000313|EMBL:AVE00942.1}; EC=3.1.3.67 {ECO:0000313|EMBL:AVE00942.1}; Flags: Fragment;+++[A0A2R4SE35_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase {ECO:0000313|EMBL:AVZ47052.1}; EC=3.1.3.67 {ECO:0000313|EMBL:AVZ47052.1}; Flags: Fragment;+++[F6KD01_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein {ECO:0000313|EMBL:ADM26756.1}; SubName: Full=Phosphatase and tensin-like protein isoform A {ECO:0000313|EMBL:AHW56562.1};+++[H6WA46_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein mutant variant 5 {ECO:0000313|EMBL:AEZ67438.1}; Flags: Fragment;+++[H6WA51_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein mutant variant 5 {ECO:0000313|EMBL:AEZ67433.1}; Flags: Fragment;+++[H6WA52_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein mutant variant 3 {ECO:0000313|EMBL:AEZ67431.1}; Flags: Fragment;"]
[57380,"'MRS2'",329,336,333,332.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0015095///magnesium ion transmembrane transporter activity","GO:0015693///magnesium ion transport+++GO:0055085///transmembrane transport+++GO:0006811///ion transport+++GO:0045016///mitochondrial magnesium ion transmembrane transport","magnesium transporter MRS2","[MRS2_HUMAN|Reviewed]RecName: Full=Magnesium transporter MRS2 homolog, mitochondrial; AltName: Full=MRS2-like protein; Flags: Precursor;+++[A0A0A0MQX2_HUMAN|Unreviewed]SubName: Full=Magnesium transporter MRS2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000274747};+++[B4DSN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52740, highly similar to Magnesium transporter MRS2L, mitochondrial {ECO:0000313|EMBL:BAG61694.1};+++[H7BZ29_HUMAN|Unreviewed]SubName: Full=Magnesium transporter MRS2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000387441}; Flags: Fragment;+++[Q96KF9_HUMAN|Unreviewed]SubName: Full=Putative magnesium transporter {ECO:0000313|EMBL:AAK38616.1}; Flags: Fragment;"]
[57407,"'NMRAL1'",703,672,728,701,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding",null,"NmrA like redox sensor 1","[NMRL1_HUMAN|Reviewed]RecName: Full=NmrA-like family domain-containing protein 1;+++[I3L0Y6_HUMAN|Unreviewed]SubName: Full=NmrA-like family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000458425}; Flags: Fragment;+++[I3L1Q7_HUMAN|Unreviewed]SubName: Full=NmrA-like family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459022};+++[I3L1Y8_HUMAN|Unreviewed]SubName: Full=NmrA-like family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459221}; Flags: Fragment;+++[I3L2U0_HUMAN|Unreviewed]SubName: Full=NmrA-like family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459926};+++[I3L3I6_HUMAN|Unreviewed]SubName: Full=NmrA-like family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000460476}; Flags: Fragment;+++[I3L3Z0_HUMAN|Unreviewed]SubName: Full=NmrA-like family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000460837}; Flags: Fragment;+++[I3L543_HUMAN|Unreviewed]SubName: Full=NmrA-like family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000461763}; Flags: Fragment;"]
[57447,"'NDRG2'",246,362,247,285,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0001818///negative regulation of cytokine production+++GO:0030154///cell differentiation+++GO:0016055///Wnt signaling pathway+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0007399///nervous system development+++GO:0007275///multicellular organism development+++GO:0010574///regulation of vascular endothelial growth factor production+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0007165///signal transduction+++GO:0090361///regulation of platelet-derived growth factor production+++GO:0021762///substantia nigra development","NDRG family member 2","[NDRG2_HUMAN|Reviewed]RecName: Full=Protein NDRG2; AltName: Full=N-myc downstream-regulated gene 2 protein; AltName: Full=Protein Syld709613;+++[A0A0A0MS87_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000380954};+++[A0A0U1RR50_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000489341}; Flags: Fragment;+++[G3V237_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450446};+++[G3V239_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450450}; Flags: Fragment;+++[G3V271_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450493}; Flags: Fragment;+++[G3V280_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450504}; Flags: Fragment;+++[G3V285_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450513}; Flags: Fragment;+++[G3V2A6_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450545}; Flags: Fragment;+++[G3V2I9_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450691}; Flags: Fragment;+++[G3V2S0_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450825}; Flags: Fragment;+++[G3V2T2_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450852}; Flags: Fragment;+++[G3V2Y3_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450929};+++[G3V358_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451059}; Flags: Fragment;+++[G3V383_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451094}; Flags: Fragment;+++[G3V392_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451105}; Flags: Fragment;+++[G3V3C3_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451163}; Flags: Fragment;+++[G3V3D5_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451185}; Flags: Fragment;+++[G3V3L1_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451302}; Flags: Fragment;+++[G3V3P1_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451348}; Flags: Fragment;+++[G3V3P6_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451353};+++[G3V3X2_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451471}; Flags: Fragment;+++[G3V3X3_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451472}; Flags: Fragment;+++[G3V420_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451541}; Flags: Fragment;+++[G3V4S2_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451951}; Flags: Fragment;+++[G3V4S9_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451966}; Flags: Fragment;+++[G3V4T9_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000451981}; Flags: Fragment;+++[G3V4X3_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452053};+++[G3V552_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452179}; Flags: Fragment;+++[G3V578_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452216};+++[G3V5A6_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452262}; Flags: Fragment;+++[G3V5B5_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452274}; Flags: Fragment;+++[G3V5B7_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452278}; Flags: Fragment;+++[G3V5D7_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452302}; Flags: Fragment;+++[G3V5G0_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452334}; Flags: Fragment;+++[G3V5G7_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452344}; Flags: Fragment;+++[G3V5H8_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452362}; Flags: Fragment;+++[G3V5L7_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452413}; Flags: Fragment;+++[G3V5P9_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452458}; Flags: Fragment;+++[G3V5S0_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452482}; Flags: Fragment;+++[G3V5V9_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452548}; Flags: Fragment;+++[H0YJ56_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000450835}; Flags: Fragment;+++[H0YJT9_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000452117}; Flags: Fragment;+++[H7C0X0_HUMAN|Unreviewed]SubName: Full=Protein NDRG2 {ECO:0000313|Ensembl:ENSP00000397250}; Flags: Fragment;"]
[57456,"'KIAA1143'",791.56,690,719,733.52,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"KIAA1143","[K1143_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA1143;+++[A0A024R2T2_HUMAN|Unreviewed]SubName: Full=KIAA1143, isoform CRA_a {ECO:0000313|EMBL:EAW64723.1};"]
[57479,"'PRR12'",1357,1662,1539,1519.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030054///cell junction+++GO:0014069///postsynaptic density+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0045202///synapse+++GO:0005634///nucleus","GO:0003677///DNA binding",null,"proline rich 12","[PRR12_HUMAN|Reviewed]RecName: Full=Proline-rich protein 12;"]
[57493,"'HEG1'",1834,2348,2346,2176,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005911///cell-cell junction+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:0001945///lymph vessel development+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:1902414///protein localization to cell junction+++GO:0050878///regulation of body fluid levels+++GO:1905709///negative regulation of membrane permeability+++GO:0055017///cardiac muscle tissue growth+++GO:0007507///heart development+++GO:0003209///cardiac atrium morphogenesis+++GO:0035264///multicellular organism growth+++GO:0045216///cell-cell junction organization+++GO:0001944///vasculature development+++GO:0048845///venous blood vessel morphogenesis+++GO:0090271///positive regulation of fibroblast growth factor production+++GO:0030324///lung development+++GO:0001885///endothelial cell development+++GO:0001701///in utero embryonic development+++GO:0001570///vasculogenesis+++GO:0001886///endothelial cell morphogenesis+++GO:2000299///negative regulation of Rho-dependent protein serine/threonine kinase activity+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003017///lymph circulation+++GO:0009791///post-embryonic development+++GO:0007043///cell-cell junction assembly+++GO:0060039///pericardium development+++GO:0007275///multicellular organism development+++GO:0003281///ventricular septum development","heart development protein with EGF like domains 1","[HEG1_HUMAN|Reviewed]RecName: Full=Protein HEG homolog 1; Flags: Precursor;+++[A0A2R8Y4Z1_HUMAN|Unreviewed]SubName: Full=Protein HEG homolog 1 {ECO:0000313|Ensembl:ENSP00000494391}; Flags: Fragment;+++[H7C4K2_HUMAN|Unreviewed]SubName: Full=Protein HEG homolog 1 {ECO:0000313|Ensembl:ENSP00000417494}; Flags: Fragment;+++[H7C4M4_HUMAN|Unreviewed]SubName: Full=Protein HEG homolog 1 {ECO:0000313|Ensembl:ENSP00000417648}; Flags: Fragment;+++[L8ECI8_HUMAN|Unreviewed]SubName: Full=Alternative protein HEG1 {ECO:0000313|EMBL:CCQ43642.1};+++[Q7Z2S9_HUMAN|Unreviewed]SubName: Full=MSTP112 {ECO:0000313|EMBL:AAQ13634.1};"]
[57522,"'SRGAP1'",300,290,273,287.666666666667,"04360///Axon guidance",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0030336///negative regulation of cell migration+++GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","SLIT-ROBO Rho GTPase activating protein 1","[SRGP1_HUMAN|Reviewed]RecName: Full=SLIT-ROBO Rho GTPase-activating protein 1; Short=srGAP1; AltName: Full=Rho GTPase-activating protein 13;+++[A0A2X0SFI2_HUMAN|Unreviewed]SubName: Full=SRGAP1 {ECO:0000313|EMBL:SPT35798.1}; Flags: Fragment;+++[G5EA48_HUMAN|Unreviewed]SubName: Full=SLIT-ROBO Rho GTPase activating protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW97122.1}; SubName: Full=SLIT-ROBO Rho GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000437948};+++[L0R5D0_HUMAN|Unreviewed]SubName: Full=Alternative protein SRGAP1 {ECO:0000313|EMBL:CCO13824.1};"]
[57538,"'ALPK3'",1520,1564,1388,1490.66666666667,{"$nulls":4},"GO:0030496///midbody+++GO:0032391///photoreceptor connecting cilium+++GO:0001917///photoreceptor inner segment+++GO:0072686///mitotic spindle+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0001750///photoreceptor outer segment+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0031514///motile cilium+++GO:0005930///axoneme+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0003713///transcription coactivator activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity","GO:0055013///cardiac muscle cell development+++GO:0042073///intraciliary transport+++GO:0010468///regulation of gene expression+++GO:0016310///phosphorylation+++GO:0007275///multicellular organism development+++GO:0045494///photoreceptor cell maintenance+++GO:0035556///intracellular signal transduction+++GO:0007507///heart development+++GO:0030154///cell differentiation+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0060271///cilium assembly+++GO:0046777///protein autophosphorylation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:1902856///negative regulation of non-motile cilium assembly","alpha kinase 3","[ALPK3_HUMAN|Reviewed]RecName: Full=Alpha-protein kinase 3 {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:Q96QP1}; AltName: Full=Muscle alpha-protein kinase {ECO:0000303|PubMed:10021370};+++[Q8IXN4_HUMAN|Unreviewed]SubName: Full=MAK protein {ECO:0000313|EMBL:AAH39825.1}; SubName: Full=Serine/threonine-protein kinase MAK {ECO:0000313|Ensembl:ENSP00000442250};"]
[57551,"'TAOK1'",1095,1024,1061,1060,"04010///MAPK signaling pathway",null,"M00688///MAPK (JNK) signaling+++M00689///MAPK (p38) signaling",null,"GO:0048471///perinuclear region of cytoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0048487///beta-tubulin binding+++GO:0050321///tau-protein kinase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004709///MAP kinase kinase kinase activity+++GO:0000166///nucleotide binding+++GO:0048156///tau protein binding+++GO:0016301///kinase activity+++GO:0043014///alpha-tubulin binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0007257///activation of JUN kinase activity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:1901985///positive regulation of protein acetylation+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0006915///apoptotic process+++GO:0000186///activation of MAPKK activity+++GO:0032147///activation of protein kinase activity+++GO:0016310///phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0051493///regulation of cytoskeleton organization+++GO:0006468///protein phosphorylation+++GO:0046330///positive regulation of JNK cascade+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0023014///signal transduction by protein phosphorylation+++GO:0006281///DNA repair+++GO:0097194///execution phase of apoptosis+++GO:0000226///microtubule cytoskeleton organization+++GO:0000187///activation of MAPK activity+++GO:0070050///neuron cellular homeostasis+++GO:0046777///protein autophosphorylation+++GO:0007026///negative regulation of microtubule depolymerization","TAO kinase 1","[TAOK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase TAO1; EC=2.7.11.1; AltName: Full=Kinase from chicken homolog B; Short=hKFC-B; AltName: Full=MARK Kinase; Short=MARKK; AltName: Full=Prostate-derived sterile 20-like kinase 2; Short=PSK-2; Short=PSK2; Short=Prostate-derived STE20-like kinase 2; AltName: Full=Thousand and one amino acid protein kinase 1; Short=TAOK1; Short=hTAOK1;+++[A0A024QZ70_HUMAN|Unreviewed]SubName: Full=TAO kinase 1, isoform CRA_a {ECO:0000313|EMBL:EAW51190.1};+++[J3QS76_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase TAO1 {ECO:0000313|Ensembl:ENSP00000464562}; Flags: Fragment;"]
[57573,"'ZNF471'",97,123,104,108,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 471","[ZN471_HUMAN|Reviewed]RecName: Full=Zinc finger protein 471; AltName: Full=EZFIT-related protein 1;+++[A0A024R4Q9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 471, isoform CRA_a {ECO:0000313|EMBL:EAW72460.1};+++[K7EPX1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 471 {ECO:0000313|Ensembl:ENSP00000467570}; Flags: Fragment;"]
[57586,"'SYT13'",7,11,15,11,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0098793///presynapse+++GO:0005887///integral component of plasma membrane+++GO:0030133///transport vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070382///exocytic vesicle","GO:0019905///syntaxin binding+++GO:0005509///calcium ion binding+++GO:0001786///phosphatidylserine binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0000149///SNARE binding+++GO:0030276///clathrin binding","GO:0016079///synaptic vesicle exocytosis+++GO:0016192///vesicle-mediated transport+++GO:0014059///regulation of dopamine secretion+++GO:0071277///cellular response to calcium ion+++GO:0017156///calcium ion regulated exocytosis","synaptotagmin 13","[SYT13_HUMAN|Reviewed]RecName: Full=Synaptotagmin-13; AltName: Full=Synaptotagmin XIII; Short=SytXIII;+++[H0YD47_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-13 {ECO:0000313|Ensembl:ENSP00000432975}; Flags: Fragment;+++[H0YE47_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-13 {ECO:0000313|Ensembl:ENSP00000434967}; Flags: Fragment;"]
[57610,"'RANBP10'",572,709,634,638.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex","GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","RAN binding protein 10","[RBP10_HUMAN|Reviewed]RecName: Full=Ran-binding protein 10; Short=RanBP10;+++[A0A0D9SEU5_HUMAN|Unreviewed]SubName: Full=Ran-binding protein 10 {ECO:0000313|Ensembl:ENSP00000486026};+++[B3KP49_HUMAN|Unreviewed]SubName: Full=RAN binding protein 10, isoform CRA_b {ECO:0000313|EMBL:EAW83168.1}; SubName: Full=cDNA FLJ31165 fis, clone KIDNE1000121, highly similar to Homo sapiens RAN binding protein 10 (RANBP10), mRNA {ECO:0000313|EMBL:BAG51561.1};+++[R4GMX7_HUMAN|Unreviewed]SubName: Full=Ran-binding protein 10 {ECO:0000313|Ensembl:ENSP00000473395};+++[R4GMX8_HUMAN|Unreviewed]SubName: Full=Ran-binding protein 10 {ECO:0000313|Ensembl:ENSP00000473396};+++[R4GN91_HUMAN|Unreviewed]SubName: Full=Ran-binding protein 10 {ECO:0000313|Ensembl:ENSP00000473538};+++[R4GNA3_HUMAN|Unreviewed]SubName: Full=Ran-binding protein 10 {ECO:0000313|Ensembl:ENSP00000473554};"]
[5763,"'PTMS'",6929,5612,6140,6227,{"$nulls":4},"GO:0005634///nucleus","GO:0042803///protein homodimerization activity","GO:0006260///DNA replication+++GO:0002376///immune system process","parathymosin","[PTMS_HUMAN|Reviewed]RecName: Full=Parathymosin;+++[A0A158RFU3_HUMAN|Unreviewed]SubName: Full=Parathymosin {ECO:0000313|EMBL:AAH17025.2};+++[A2VCM6_HUMAN|Unreviewed]SubName: Full=PTMS protein {ECO:0000313|EMBL:AAI28230.1}; Flags: Fragment;+++[F5GXR3_HUMAN|Unreviewed]SubName: Full=Parathymosin {ECO:0000313|Ensembl:ENSP00000374113};+++[F5H7R9_HUMAN|Unreviewed]SubName: Full=Parathymosin {ECO:0000313|Ensembl:ENSP00000442325}; Flags: Fragment;+++[O15256_HUMAN|Unreviewed]SubName: Full=Parathymosin {ECO:0000313|EMBL:CAA73913.1}; Flags: Fragment;"]
[57648,"'KIAA1522'",3195,3454,3353,3334,{"$nulls":6},"GO:0030154///cell differentiation","KIAA1522","[K1522_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA1522;"]
[57678,"'GPAM'",278,271,302,283.666666666667,"01110///Biosynthesis of secondary metabolites+++00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++01100///Metabolic pathways",null,"M00089///Triacylglycerol biosynthesis","R00851///acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase   sn-Glycerol 3-phosphate + Acyl-CoA <=> 1-Acyl-sn-glycerol 3-phosphate + CoA+++R09380///acyl-ACP:sn-glycerol-3-phosphate 1-O-acyltransferase   Acyl-[acyl-carrier protein] + sn-Glycerol 3-phosphate <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-carrier protein","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0031966///mitochondrial membrane","GO:0102420///sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity+++GO:0008374///O-acyltransferase activity+++GO:0004366///glycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0051607///defense response to virus+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0070236///negative regulation of activation-induced cell death of T cells+++GO:0006629///lipid metabolic process+++GO:0040018///positive regulation of multicellular organism growth+++GO:0055091///phospholipid homeostasis+++GO:0070970///interleukin-2 secretion+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0044255///cellular lipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0055089///fatty acid homeostasis+++GO:0050707///regulation of cytokine secretion+++GO:0006641///triglyceride metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0009749///response to glucose+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0019432///triglyceride biosynthetic process","glycerol-3-phosphate acyltransferase, mitochondrial","[GPAT1_HUMAN|Reviewed]RecName: Full=Glycerol-3-phosphate acyltransferase 1, mitochondrial; Short=GPAT-1; EC=2.3.1.15; Flags: Precursor;+++[Q5VW52_HUMAN|Unreviewed]RecName: Full=Glycerol-3-phosphate acyltransferase 1, mitochondrial {ECO:0000256|PIRNR:PIRNR000437}; EC=2.3.1.15 {ECO:0000256|PIRNR:PIRNR000437};+++[Q86T70_HUMAN|Unreviewed]RecName: Full=Glycerol-3-phosphate acyltransferase 1, mitochondrial {ECO:0000256|PIRNR:PIRNR000437}; EC=2.3.1.15 {ECO:0000256|PIRNR:PIRNR000437};+++[Q8N1G6_HUMAN|Unreviewed]RecName: Full=Glycerol-3-phosphate acyltransferase 1, mitochondrial {ECO:0000256|PIRNR:PIRNR000437}; EC=2.3.1.15 {ECO:0000256|PIRNR:PIRNR000437};"]
[57696,"'DDX55'",220,296,209,241.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity","GO:0010501///RNA secondary structure unwinding","DEAD-box helicase 55","[DDX55_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX55; EC=3.6.4.13; AltName: Full=DEAD box protein 55;+++[A0A024RBS0_HUMAN|Unreviewed]RecName: Full=RNA helicase {ECO:0000256|SAAS:SAAS00892872}; EC=3.6.4.13 {ECO:0000256|SAAS:SAAS00892872};+++[E7EX41_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX55 {ECO:0000313|Ensembl:ENSP00000346244};+++[F5H2I2_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX55 {ECO:0000313|Ensembl:ENSP00000446255};+++[F5H5U2_HUMAN|Unreviewed]RecName: Full=RNA helicase {ECO:0000256|SAAS:SAAS00892872}; EC=3.6.4.13 {ECO:0000256|SAAS:SAAS00892872};+++[F5H735_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX55 {ECO:0000313|Ensembl:ENSP00000442823};"]
[57713,"'SFMBT2'",15,17,23,18.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016235///aggresome","GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0042393///histone binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0010629///negative regulation of gene expression+++GO:0006355///regulation of transcription, DNA-templated","Scm like with four mbt domains 2","[SMBT2_HUMAN|Reviewed]RecName: Full=Scm-like with four MBT domains protein 2; Short=Scm-like with 4 MBT domains protein 2;+++[Q5T980_HUMAN|Unreviewed]SubName: Full=Scm-like with four MBT domains protein 2 {ECO:0000313|Ensembl:ENSP00000369033};+++[Q5T981_HUMAN|Unreviewed]SubName: Full=Scm-like with four MBT domains protein 2 {ECO:0000313|Ensembl:ENSP00000369035};"]
[5774,"'PTPN3'",201,250,220,223.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0051117///ATPase binding+++GO:0008092///cytoskeletal protein binding+++GO:0016787///hydrolase activity+++GO:0017080///sodium channel regulator activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0001784///phosphotyrosine residue binding","GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0097421///liver regeneration+++GO:2000649///regulation of sodium ion transmembrane transporter activity+++GO:0098902///regulation of membrane depolarization during action potential+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0016311///dephosphorylation+++GO:0006470///protein dephosphorylation","protein tyrosine phosphatase, non-receptor type 3","[PTN3_HUMAN|Reviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type 3; EC=3.1.3.48; AltName: Full=Protein-tyrosine phosphatase H1; Short=PTP-H1;+++[B7Z3V3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59556, highly similar to Tyrosine-protein phosphatase non-receptor type3 {ECO:0000313|EMBL:BAH12339.1};+++[B7Z9V1_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type {ECO:0000256|PIRNR:PIRNR000927}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR000927};+++[B7ZA03_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79017, highly similar to Tyrosine-protein phosphatase non-receptor type3 {ECO:0000313|EMBL:BAH14489.1};+++[J3KN34_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type {ECO:0000256|PIRNR:PIRNR000927}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR000927};+++[Q8N4S3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAH33716.1}; Flags: Fragment;"]
[57805,"'CCAR2'",1892,2033,1901,1942,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0044609///DBIRD complex+++GO:0005681///spliceosomal complex+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005759///mitochondrial matrix","GO:0004857///enzyme inhibitor activity+++GO:0003723///RNA binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding","GO:0006397///mRNA processing+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0090311///regulation of protein deacetylation+++GO:0008380///RNA splicing+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031647///regulation of protein stability+++GO:0016055///Wnt signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0043086///negative regulation of catalytic activity+++GO:0048511///rhythmic process+++GO:0042752///regulation of circadian rhythm+++GO:0009411///response to UV+++GO:0007049///cell cycle+++GO:1900034///regulation of cellular response to heat+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:2000003///positive regulation of DNA damage checkpoint+++GO:0030308///negative regulation of cell growth+++GO:0006355///regulation of transcription, DNA-templated+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","cell cycle and apoptosis regulator 2","[CCAR2_HUMAN|Reviewed]RecName: Full=Cell cycle and apoptosis regulator protein 2; AltName: Full=Cell division cycle and apoptosis regulator protein 2; AltName: Full=DBIRD complex subunit KIAA1967; AltName: Full=Deleted in breast cancer gene 1 protein; Short=DBC-1; Short=DBC.1; AltName: Full=NET35; AltName: Full=p30 DBC;+++[A0A087X2B6_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000484850};+++[E5RFJ3_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000428843}; Flags: Fragment;+++[E5RGU7_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000430978}; Flags: Fragment;+++[E5RHH8_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000429769};+++[E5RHJ4_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000429739}; Flags: Fragment;+++[G3V119_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000429773}; SubName: Full=KIAA1967, isoform CRA_b {ECO:0000313|EMBL:EAW63659.1};+++[H0YB24_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000428549}; Flags: Fragment;+++[H0YC58_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000430974}; Flags: Fragment;+++[H0YC69_HUMAN|Unreviewed]SubName: Full=Cell cycle and apoptosis regulator protein 2 {ECO:0000313|Ensembl:ENSP00000431046}; Flags: Fragment;"]
[5784,"'PTPN14'",2578,2770,2732.91,2693.63666666667,null,"H01017///Choanal atresia and lymphedema",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0030971///receptor tyrosine kinase binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003712///transcription coregulator activity+++GO:0016791///phosphatase activity","GO:0008285///negative regulation of cell proliferation+++GO:0006470///protein dephosphorylation+++GO:0046825///regulation of protein export from nucleus+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0001946///lymphangiogenesis+++GO:0016311///dephosphorylation+++GO:1903506///regulation of nucleic acid-templated transcription+++GO:0071345///cellular response to cytokine stimulus","protein tyrosine phosphatase, non-receptor type 14","[PTN14_HUMAN|Reviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type 14; EC=3.1.3.48; AltName: Full=Protein-tyrosine phosphatase pez;+++[A8K6H6_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type {ECO:0000256|PIRNR:PIRNR000934}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR000934};+++[E2J9M0_HUMAN|Unreviewed]SubName: Full=Truncated protein tyrosine phosphatase non-receptor type 14 {ECO:0000313|EMBL:ADN23590.1}; EC=3.1.3.48 {ECO:0000313|EMBL:ADN23590.1}; SubName: Full=Tyrosine-protein phosphatase non-receptor type 14 {ECO:0000313|Ensembl:ENSP00000443330};+++[Q6PJC3_HUMAN|Unreviewed]SubName: Full=PTPN14 protein {ECO:0000313|EMBL:AAH17300.1}; Flags: Fragment;"]
[57862,"'ZNF410'",344,290,333,322.333333333333,"01200///Carbon metabolism+++00230///Purine metabolism+++00280///Valine, leucine and isoleucine degradation+++00240///Pyrimidine metabolism+++00410///beta-Alanine metabolism+++00562///Inositol phosphate metabolism+++00640///Propanoate metabolism+++01100///Metabolic pathways",null,"M00013///Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA","R00155///UDP phosphohydrolase UDP + H2O <=> UMP + Orthophosphate+++R00328///GDP phosphohydrolase GDP + H2O <=> GMP + Orthophosphate+++R00706///3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating) 3-Oxopropanoate + CoA + NADP+ <=> Acetyl-CoA + CO2 + NADPH + H++++R00922///2-Methyl-3-oxopropanoate:NAD+ oxidoreductase (CoA-propanoylating) 2-Methyl-3-oxopropanoate + CoA + NAD+ <=> Propanoyl-CoA + CO2 + NADH + H++++R00705///3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating) 3-Oxopropanoate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H++++R00961///IDP phosphohydrolase; inosine IDP + H2O <=> IMP + Orthophosphate+++R00935///(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase (CoA-propanoylating) (S)-Methylmalonate semialdehyde + CoA + NAD+ <=> Propanoyl-CoA + CO2 + NADH + H+","GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 410","[ZN410_HUMAN|Reviewed]RecName: Full=Zinc finger protein 410; AltName: Full=Another partner for ARF 1; AltName: Full=Zinc finger protein APA-1;+++[A0A024R691_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410, isoform CRA_b {ECO:0000313|EMBL:EAW81138.1};+++[A0A1W2PNT4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000490985};+++[B4DPW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410, isoform CRA_c {ECO:0000313|EMBL:EAW81139.1}; SubName: Full=cDNA FLJ53155, highly similar to Zinc finger protein 410 {ECO:0000313|EMBL:BAG60724.1};+++[G3V2C2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000450569}; Flags: Fragment;+++[G3V2G5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000450650};+++[G3V2V5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000450884}; Flags: Fragment;+++[G3V369_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000451073};+++[G3V398_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000451116}; Flags: Fragment;+++[G3V3W2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000451458}; Flags: Fragment;+++[G3V4E6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000451748}; Flags: Fragment;+++[G3V4H7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000451807}; Flags: Fragment;+++[G3V4W2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000452023}; Flags: Fragment;+++[G3V565_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000452199}; Flags: Fragment;+++[H0YJI7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000451620}; Flags: Fragment;+++[J3KNQ6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 410 {ECO:0000313|Ensembl:ENSP00000334170};+++[Q53FM1_HUMAN|Unreviewed]SubName: Full=Clones 23667 and 23775 zinc finger protein variant {ECO:0000313|EMBL:BAD96981.1}; Flags: Fragment;"]
[5798,"'PTPRN'",42,47,53,47.3333333333333,"04940///Type I diabetes mellitus",{"$nulls":3},"GO:0043204///perikaryon+++GO:0005768///endosome+++GO:0008021///synaptic vesicle+++GO:0043025///neuronal cell body+++GO:0043679///axon terminus+++GO:0030658///transport vesicle membrane+++GO:0030424///axon+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0031410///cytoplasmic vesicle","GO:0051020///GTPase binding+++GO:0005515///protein binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0008134///transcription factor binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0030507///spectrin binding+++GO:0016791///phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0043627///response to estrogen+++GO:0000302///response to reactive oxygen species+++GO:0051591///response to cAMP+++GO:0032868///response to insulin+++GO:0009749///response to glucose+++GO:0001553///luteinization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030073///insulin secretion+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus+++GO:0019221///cytokine-mediated signaling pathway+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:1990502///dense core granule maturation+++GO:1904692///positive regulation of type B pancreatic cell proliferation","protein tyrosine phosphatase, receptor type N","[PTPRN_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase-like N; Short=R-PTP-N; AltName: Full=Islet cell antigen 512 {ECO:0000303|PubMed:8144912}; Short=ICA 512 {ECO:0000303|PubMed:8641276}; AltName: Full=Islet cell autoantigen 3; AltName: Full=PTP IA-2; Contains: RecName: Full=ICA512-N-terminal fragment; Short=ICA512-NTF; Contains: RecName: Full=ICA512-transmembrane fragment; Short=ICA512-TMF; Contains: RecName: Full=ICA512-cleaved cytosolic fragment; Short=ICA512-CCF; Flags: Precursor;+++[A0A1B0GX26_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSP00000388429}; Flags: Fragment;+++[C9J392_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSP00000397105}; Flags: Fragment;+++[C9JCQ0_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSP00000396464}; Flags: Fragment;+++[C9JJL7_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSP00000395379}; Flags: Fragment;+++[C9JR27_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSP00000408036}; Flags: Fragment;+++[H7C0U9_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSP00000396842}; Flags: Fragment;+++[Q7KZS4_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase, receptor type, N, isoform CRA_b {ECO:0000313|EMBL:EAW70725.1};+++[Q96IA0_HUMAN|Unreviewed]SubName: Full=PTPRN protein {ECO:0000313|EMBL:AAH07713.2}; Flags: Fragment;+++[U3KQ66_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase-like N {ECO:0000313|Ensembl:ENSP00000475591};"]
[5816,"'PVALB'",4,2,1,2.33333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity+++GO:0005509///calcium ion binding","GO:0051480///regulation of cytosolic calcium ion concentration","parvalbumin","[PRVA_HUMAN|Reviewed]RecName: Full=Parvalbumin alpha;+++[A0A024R1K9_HUMAN|Unreviewed]SubName: Full=Parvalbumin, isoform CRA_a {ECO:0000313|EMBL:EAW60120.1};+++[B1AH72_HUMAN|Unreviewed]SubName: Full=Parvalbumin alpha {ECO:0000313|Ensembl:ENSP00000386089};+++[B8ZZ19_HUMAN|Unreviewed]SubName: Full=Parvalbumin alpha {ECO:0000313|Ensembl:ENSP00000406977}; Flags: Fragment;+++[H0Y3U0_HUMAN|Unreviewed]SubName: Full=Parvalbumin alpha {ECO:0000313|Ensembl:ENSP00000384735}; Flags: Fragment;"]
[5833,"'PCYT2'",735,815,793,781,"00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism+++01100///Metabolic pathways",null,"M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE","R04247///CTP:ethanolamine-phosphate cytidylyltransferase   CTP + 2-Aminoethylphosphonate <=> Diphosphate + CMP-2-aminoethylphosphonate+++R02038///CTP:ethanolamine-phosphate cytidylyltransferase   CTP + Ethanolamine phosphate <=> Diphosphate + CDP-ethanolamine","GO:0005789///endoplasmic reticulum membrane+++GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0004306///ethanolamine-phosphate cytidylyltransferase activity+++GO:0003824///catalytic activity+++GO:0016779///nucleotidyltransferase activity","GO:0009058///biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006629///lipid metabolic process","phosphate cytidylyltransferase 2, ethanolamine","[PCY2_HUMAN|Reviewed]RecName: Full=Ethanolamine-phosphate cytidylyltransferase; EC=2.7.7.14; AltName: Full=CTP:phosphoethanolamine cytidylyltransferase; AltName: Full=Phosphorylethanolamine transferase;+++[B3KSC8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36009 fis, clone TESTI2015675, highly similar to Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|EMBL:BAG52690.1};+++[B7Z4W6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55495, highly similar to Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|EMBL:BAH12702.1};+++[I3L102_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000458472};+++[I3L1C4_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000458727}; Flags: Fragment;+++[I3L1F9_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000458805}; Flags: Fragment;+++[I3L1L9_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000458931}; Flags: Fragment;+++[I3L1R7_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000459044};+++[I3L2Q1_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000459836}; Flags: Fragment;+++[I3L3V9_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000460767}; Flags: Fragment;+++[I3NI16_HUMAN|Unreviewed]SubName: Full=Ethanolamine-phosphate cytidylyltransferase {ECO:0000313|Ensembl:ENSP00000461814}; Flags: Fragment;"]
[58487,"'CREBZF'",350,385,379,371.333333333333,null,"H01020///Optic atrophy (OPA)",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0045814///negative regulation of gene expression, epigenetic+++GO:0009615///response to virus+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","CREB/ATF bZIP transcription factor","[ZHANG_HUMAN|Reviewed]RecName: Full=CREB/ATF bZIP transcription factor; AltName: Full=Host cell factor-binding transcription factor Zhangfei; Short=HCF-binding transcription factor Zhangfei;+++[E9PIM0_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000435762};+++[E9PRP7_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000435980};+++[H0YDC7_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000433380}; Flags: Fragment;+++[J3KN20_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000260058}; Flags: Fragment;"]
[58512,"'DLGAP3'",22,23,24,23,{"$nulls":4},"GO:0099572///postsynaptic specialization+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0098978///glutamatergic synapse+++GO:0005840///ribosome+++GO:0005761///mitochondrial ribosome+++GO:0015935///small ribosomal subunit+++GO:0098981///cholinergic synapse+++GO:0045202///synapse+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005739///mitochondrion+++GO:0045211///postsynaptic membrane+++GO:0005743///mitochondrial inner membrane+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0001540///amyloid-beta binding+++GO:0005525///GTP binding","GO:0097190///apoptotic signaling pathway+++GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination+++GO:0006915///apoptotic process+++GO:0099563///modification of synaptic structure+++GO:0023052///signaling","DLG associated protein 3","[DLGP3_HUMAN|Reviewed]RecName: Full=Disks large-associated protein 3; Short=DAP-3; AltName: Full=PSD-95/SAP90-binding protein 3; AltName: Full=SAP90/PSD-95-associated protein 3; Short=SAPAP3;+++[A4FUA4_HUMAN|Unreviewed]SubName: Full=DLGAP3 protein {ECO:0000313|EMBL:AAI14370.1}; Flags: Fragment;+++[A4QMX6_HUMAN|Unreviewed]SubName: Full=DLGAP3 protein {ECO:0000313|EMBL:AAI14371.1}; Flags: Fragment;+++[V9GY11_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476291}; Flags: Fragment;+++[V9GYA7_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476558}; Flags: Fragment;+++[V9GYC9_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476624}; Flags: Fragment;+++[V9GYF7_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476706}; Flags: Fragment;+++[V9GYJ3_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476816}; Flags: Fragment;+++[V9GYJ9_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476840}; Flags: Fragment;+++[V9GYL4_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476889};+++[V9GYL9_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000476899}; Flags: Fragment;+++[V9GYR8_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000477025}; Flags: Fragment;+++[V9GYW1_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000477139}; Flags: Fragment;+++[V9GZ03_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000477265}; Flags: Fragment;+++[V9GZ61_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S29, mitochondrial {ECO:0000313|Ensembl:ENSP00000477453}; Flags: Fragment;"]
[58538,"'MPP4'",0,0,2,0.666666666666667,"04530///Tight junction",{"$nulls":3},"GO:0005829///cytosol+++GO:0005913///cell-cell adherens junction+++GO:0015629///actin cytoskeleton+++GO:0032991///protein-containing complex",null,"GO:0035418///protein localization to synapse","membrane palmitoylated protein 4","[MPP4_HUMAN|Reviewed]RecName: Full=MAGUK p55 subfamily member 4; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein; AltName: Full=Discs large homolog 6;+++[A0A087WUS1_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000478875};+++[A2RU80_HUMAN|Unreviewed]SubName: Full=MPP4 protein {ECO:0000313|EMBL:AAI32786.1};+++[B7ZM19_HUMAN|Unreviewed]SubName: Full=MPP4 protein {ECO:0000313|EMBL:AAI44207.1};+++[E7ET46_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000416781};+++[E7EUL8_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000406160};+++[E9PG92_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000380095};+++[F6Q0Y6_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000387293};+++[F8WBH8_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000386580};+++[R4GN59_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000473500}; Flags: Fragment;"]
[5872,"'RAB13'",1276,1344,1093,1237.66666666667,"04530///Tight junction",{"$nulls":3},"GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0005923///bicellular tight junction+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0055038///recycling endosome membrane+++GO:0055037///recycling endosome+++GO:0070062///extracellular exosome+++GO:0005768///endosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0032593///insulin-responsive compartment+++GO:0005802///trans-Golgi network+++GO:0030139///endocytic vesicle+++GO:0043005///neuron projection+++GO:0016328///lateral plasma membrane+++GO:0030027///lamellipodium","GO:0005525///GTP binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding","GO:0043687///post-translational protein modification+++GO:0032482///Rab protein signal transduction+++GO:0006886///intracellular protein transport+++GO:0097368///establishment of Sertoli cell barrier+++GO:0044795///trans-Golgi network to recycling endosome transport+++GO:0035767///endothelial cell chemotaxis+++GO:0030866///cortical actin cytoskeleton organization+++GO:0010737///protein kinase A signaling+++GO:0072659///protein localization to plasma membrane+++GO:0032456///endocytic recycling+++GO:0031175///neuron projection development+++GO:0016197///endosomal transport+++GO:0070830///bicellular tight junction assembly+++GO:0015031///protein transport+++GO:0032869///cellular response to insulin stimulus","RAB13, member RAS oncogene family","[RAB13_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-13; AltName: Full=Cell growth-inhibiting gene 4 protein; Flags: Precursor;+++[A0A087WWB9_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-13 {ECO:0000313|Ensembl:ENSP00000480103};+++[Q504R6_HUMAN|Unreviewed]SubName: Full=RAB13 protein {ECO:0000313|EMBL:AAH94846.1}; Flags: Fragment;"]
[5896,"'RAG1'",35,46,30,37,"05340///Primary immunodeficiency+++04068///FoxO signaling pathway","H00092///T-B-Severe combined immunodeficiencies (SCIDs)+++H00093///Combined immunodeficiencies (CIDs)+++H01244///T+B+Severe combined immunodeficiencies (SCIDs)",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004519///endonuclease activity+++GO:0003824///catalytic activity+++GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0042393///histone binding+++GO:0043565///sequence-specific DNA binding+++GO:0042803///protein homodimerization activity","GO:0016567///protein ubiquitination+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0070233///negative regulation of T cell apoptotic process+++GO:2000822///regulation of behavioral fear response+++GO:0051865///protein autoubiquitination+++GO:0033077///T cell differentiation in thymus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0045582///positive regulation of T cell differentiation+++GO:0030183///B cell differentiation+++GO:0006325///chromatin organization+++GO:0043029///T cell homeostasis+++GO:0008152///metabolic process+++GO:0002250///adaptive immune response+++GO:0010390///histone monoubiquitination+++GO:0006310///DNA recombination+++GO:0006955///immune response+++GO:0045580///regulation of T cell differentiation+++GO:0033151///V(D)J recombination+++GO:0002331///pre-B cell allelic exclusion+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0048538///thymus development+++GO:0008542///visual learning","recombination activating 1","[RAG1_HUMAN|Reviewed]RecName: Full=V(D)J recombination-activating protein 1; Short=RAG-1; AltName: Full=RING finger protein 74; Includes: RecName: Full=Endonuclease RAG1; EC=3.1.-.-; Includes: RecName: Full=E3 ubiquitin-protein ligase RAG1; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase RAG1 {ECO:0000305};+++[Q9BYY2_HUMAN|Unreviewed]SubName: Full=Recombination activating protein 1 {ECO:0000313|EMBL:AAG38421.1}; Flags: Fragment;"]
[5905,"'RANGAP1'",1949,1856,1894,1899.66666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0005643///nuclear pore+++GO:0000775///chromosome, centromeric region+++GO:0016235///aggresome+++GO:0005819///spindle+++GO:1904115///axon cytoplasm+++GO:0000777///condensed chromosome kinetochore+++GO:0030425///dendrite+++GO:0072686///mitotic spindle+++GO:0031965///nuclear membrane+++GO:0005635///nuclear envelope+++GO:0000776///kinetochore+++GO:0048471///perinuclear region of cytoplasm+++GO:0005856///cytoskeleton+++GO:0044614///nuclear pore cytoplasmic filaments+++GO:1990723///cytoplasmic periphery of the nuclear pore complex","GO:0008536///Ran GTPase binding+++GO:0003723///RNA binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0031625///ubiquitin protein ligase binding","GO:0007165///signal transduction+++GO:1904117///cellular response to vasopressin+++GO:0046826///negative regulation of protein export from nucleus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0048678///response to axon injury+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity","Ran GTPase activating protein 1","[RAGP1_HUMAN|Reviewed]RecName: Full=Ran GTPase-activating protein 1; Short=RanGAP1;+++[A0A024R1U0_HUMAN|Unreviewed]SubName: Full=Ran GTPase activating protein 1, isoform CRA_d {ECO:0000313|EMBL:EAW60424.1};+++[B0QYT4_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000394787}; Flags: Fragment;+++[B0QYT5_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000408743}; Flags: Fragment;+++[B0QYT6_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000404842}; Flags: Fragment;+++[H0Y4Q3_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000393407}; Flags: Fragment;+++[Q9BSK3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAH04990.1}; Flags: Fragment;"]
[5927,"'KDM5A'",605,608,632,615,null,"H00658///Syndromic X-linked mental retardation",null,null,"GO:0035097///histone methyltransferase complex+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0032993///protein-DNA complex+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0051213///dioxygenase activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0016491///oxidoreductase activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042393///histone binding+++GO:0032452///histone demethylase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0035064///methylated histone binding+++GO:0005515///protein binding+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0034648///histone demethylase activity (H3-dimethyl-K4 specific)+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0031490///chromatin DNA binding","GO:0007283///spermatogenesis+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific+++GO:0007275///multicellular organism development+++GO:0032922///circadian regulation of gene expression+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0008584///male gonad development+++GO:0006325///chromatin organization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0033169///histone H3-K9 demethylation+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0055114///oxidation-reduction process+++GO:1901726///negative regulation of histone deacetylase activity+++GO:0034720///histone H3-K4 demethylation+++GO:0048511///rhythmic process","lysine demethylase 5A","[KDM5A_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 5A; EC=1.14.11.-; AltName: Full=Histone demethylase JARID1A; AltName: Full=Jumonji/ARID domain-containing protein 1A; AltName: Full=Retinoblastoma-binding protein 2; Short=RBBP-2;+++[E7EV89_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5A {ECO:0000313|Ensembl:ENSP00000440622}; Flags: Fragment;+++[F5GZ99_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5A {ECO:0000313|Ensembl:ENSP00000443854}; Flags: Fragment;+++[F5GZR8_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5A {ECO:0000313|Ensembl:ENSP00000444251}; Flags: Fragment;+++[F5H322_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5A {ECO:0000313|Ensembl:ENSP00000438203}; Flags: Fragment;"]
[59285,"'CACNG6'",16,35,18,23,"04010///MAPK signaling pathway+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++05410///Hypertrophic cardiomyopathy (HCM)+++04921///Oxytocin signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes",{"$nulls":3},"GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:1990454///L-type voltage-gated calcium channel complex+++GO:0016021///integral component of membrane","GO:0005262///calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity","GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0070588///calcium ion transmembrane transport","calcium voltage-gated channel auxiliary subunit gamma 6","[CCG6_HUMAN|Reviewed]RecName: Full=Voltage-dependent calcium channel gamma-6 subunit; AltName: Full=Neuronal voltage-gated calcium channel gamma-6 subunit;+++[A6NFR2_HUMAN|Unreviewed]RecName: Full=Voltage-dependent calcium channel gamma-6 subunit {ECO:0000256|RuleBase:RU363085};+++[A6NP74_HUMAN|Unreviewed]SubName: Full=Calcium channel, voltage-dependent, gamma subunit 6, isoform CRA_c {ECO:0000313|EMBL:EAW72172.1}; SubName: Full=Voltage-dependent calcium channel gamma-6 subunit {ECO:0000313|Ensembl:ENSP00000319135};"]
[59344,"'ALOXE3'",0,0,2,0.666666666666667,null,"H00734///Autosomal recessive congenital ichthyosis",null,"R10766///hydroperoxyicosatetraenoate hydroxymutase   Hydroperoxyicosatetraenoate <=> Hydroxyepoxyicosatrienoate+++R10761///hydroperoxyicosatetraenoate hydro-lyase (oxoicosatetraenoate-forming)   Hydroperoxyicosatetraenoate <=> Oxoicosatetraenoate + H2O","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0016853///isomerase activity+++GO:0005515///protein binding+++GO:0051120///hepoxilin A3 synthase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0016829///lyase activity+++GO:0051213///dioxygenase activity+++GO:0005506///iron ion binding","GO:0055114///oxidation-reduction process+++GO:0019369///arachidonic acid metabolic process+++GO:0045444///fat cell differentiation+++GO:0006631///fatty acid metabolic process+++GO:0051122///hepoxilin biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0019233///sensory perception of pain+++GO:0046513///ceramide biosynthetic process+++GO:0061436///establishment of skin barrier+++GO:0043651///linoleic acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0019372///lipoxygenase pathway","arachidonate lipoxygenase 3","[LOXE3_HUMAN|Reviewed]RecName: Full=Hydroperoxide isomerase ALOXE3; EC=5.4.4.7 {ECO:0000269|PubMed:12881489, ECO:0000269|PubMed:17045234, ECO:0000269|PubMed:20921226, ECO:0000269|PubMed:20923767, ECO:0000269|PubMed:21558561}; AltName: Full=Epidermis-type lipoxygenase 3 {ECO:0000303|PubMed:11350124}; Short=Epidermal LOX-3; Short=e-LOX-3; Short=eLOX-3; AltName: Full=Hydroperoxy icosatetraenoate dehydratase; EC=4.2.1.152 {ECO:0000269|PubMed:12881489, ECO:0000269|PubMed:17045234, ECO:0000269|PubMed:20921226, ECO:0000269|PubMed:20923767, ECO:0000269|PubMed:21558561};+++[J3KPH2_HUMAN|Unreviewed]SubName: Full=Arachidonate lipoxygenase 3, isoform CRA_a {ECO:0000313|EMBL:EAW90093.1}; SubName: Full=Hydroperoxide isomerase ALOXE3 {ECO:0000313|Ensembl:ENSP00000369494};"]
[5970,"'RELA'",2343,2512,2385,2413.33333333333,"05140///Leishmaniasis+++04151///PI3K-Akt signaling pathway+++05160///Hepatitis C+++04658///Th1 and Th2 cell differentiation+++05162///Measles+++05134///Legionellosis+++04926///Relaxin signaling pathway+++05145///Toxoplasmosis+++05030///Cocaine addiction+++05161///Hepatitis B+++05152///Tuberculosis+++04621///NOD-like receptor signaling pathway+++04210///Apoptosis+++05202///Transcriptional misregulation in cancer+++04917///Prolactin signaling pathway+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++04659///Th17 cell differentiation+++05163///Human cytomegalovirus infection+++05222///Small cell lung cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05220///Chronic myeloid leukemia+++05221///Acute myeloid leukemia+++05168///Herpes simplex infection+++04722///Neurotrophin signaling pathway+++04064///NF-kappa B signaling pathway+++04931///Insulin resistance+++04218///Cellular senescence+++05146///Amoebiasis+++04211///Longevity regulating pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04010///MAPK signaling pathway+++05165///Human papillomavirus infection+++04062///Chemokine signaling pathway+++04662///B cell receptor signaling pathway+++05166///HTLV-I infection+++05131///Shigellosis+++05133///Pertussis+++04137///Mitophagy - animal+++04657///IL-17 signaling pathway+++04920///Adipocytokine signaling pathway+++05321///Inflammatory bowel disease (IBD)+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04620///Toll-like receptor signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05212///Pancreatic cancer+++04380///Osteoclast differentiation+++04623///Cytosolic DNA-sensing pathway+++04660///T cell receptor signaling pathway+++04071///Sphingolipid signaling pathway+++04014///Ras signaling pathway+++04024///cAMP signaling pathway+++04066///HIF-1 signaling pathway+++01523///Antifolate resistance+++04668///TNF signaling pathway+++05132///Salmonella infection+++04622///RIG-I-like receptor signaling pathway+++05215///Prostate cancer+++05418///Fluid shear stress and atherosclerosis+++04625///C-type lectin receptor signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++05203///Viral carcinogenesis+++05164///Influenza A",null,"M00686///Toll-like receptor signaling",null,"GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0035525///NF-kappaB p50/p65 complex+++GO:0005730///nucleolus+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0071159///NF-kappaB complex+++GO:0005634///nucleus+++GO:0098978///glutamatergic synapse+++GO:0005667///transcription factor complex","GO:0042805///actinin binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0047485///protein N-terminus binding+++GO:0033613///activating transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0071532///ankyrin repeat binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0042826///histone deacetylase binding+++GO:0019899///enzyme binding+++GO:0003677///DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0044877///protein-containing complex binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0042301///phosphate ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0042803///protein homodimerization activity+++GO:0031490///chromatin DNA binding+++GO:0019901///protein kinase binding+++GO:0070491///repressing transcription factor binding+++GO:0051059///NF-kappaB binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0042802///identical protein binding","GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006117///acetaldehyde metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0051607///defense response to virus+++GO:0034097///response to cytokine+++GO:0051591///response to cAMP+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010224///response to UV-B+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0038061///NIK/NF-kappaB signaling+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0045084///positive regulation of interleukin-12 biosynthetic process+++GO:2000630///positive regulation of miRNA metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0001942///hair follicle development+++GO:0032868///response to insulin+++GO:0070301///cellular response to hydrogen peroxide+++GO:0010035///response to inorganic substance+++GO:0006954///inflammatory response+++GO:0006351///transcription, DNA-templated+++GO:0071222///cellular response to lipopolysaccharide+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:0001889///liver development+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:0014040///positive regulation of Schwann cell differentiation+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0014070///response to organic cyclic compound+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0042177///negative regulation of protein catabolic process+++GO:0071347///cellular response to interleukin-1+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:0070555///response to interleukin-1+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0016032///viral process+++GO:0042493///response to drug+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:0006355///regulation of transcription, DNA-templated+++GO:0009612///response to mechanical stimulus+++GO:0071316///cellular response to nicotine+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0043278///response to morphine+++GO:0007568///aging+++GO:0032495///response to muramyl dipeptide+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0032481///positive regulation of type I interferon production+++GO:0071224///cellular response to peptidoglycan+++GO:0033590///response to cobalamin+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0043200///response to amino acid+++GO:0033234///negative regulation of protein sumoylation+++GO:0006325///chromatin organization+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0010033///response to organic substance+++GO:0006952///defense response+++GO:0070431///nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0042542///response to hydrogen peroxide+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0071356///cellular response to tumor necrosis factor+++GO:0035994///response to muscle stretch+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:0099527///postsynapse to nucleus signaling pathway+++GO:0009617///response to bacterium+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0071354///cellular response to interleukin-6+++GO:0032496///response to lipopolysaccharide+++GO:0032570///response to progesterone+++GO:0071223///cellular response to lipoteichoic acid+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0050727///regulation of inflammatory response+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0009887///animal organ morphogenesis+++GO:0006968///cellular defense response+++GO:1904385///cellular response to angiotensin","RELA proto-oncogene, NF-kB subunit","[TF65_HUMAN|Reviewed]RecName: Full=Transcription factor p65; AltName: Full=Nuclear factor NF-kappa-B p65 subunit; AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3;+++[A0A087WVP0_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000479572};+++[A0A087X0W8_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000483705};+++[E9PI38_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000436545}; Flags: Fragment;+++[E9PJR1_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000435531}; Flags: Fragment;+++[E9PJZ9_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000433616}; Flags: Fragment;+++[E9PKH5_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000433526}; Flags: Fragment;+++[E9PKV4_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000435290};+++[E9PM47_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000433144};+++[E9PMD5_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000431153}; Flags: Fragment;+++[E9PN69_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000432922};+++[E9PNK5_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000434745};+++[E9PNV4_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000437137};+++[E9PQS6_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000434372}; Flags: Fragment;+++[E9PRX2_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000434098}; Flags: Fragment;+++[E9PSE4_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000434008};+++[H0YCB4_HUMAN|Unreviewed]SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000431304}; Flags: Fragment;+++[L0R6N5_HUMAN|Unreviewed]SubName: Full=Alternative protein RELA {ECO:0000313|EMBL:CCO13802.1};+++[Q2TAM5_HUMAN|Unreviewed]SubName: Full=RELA protein {ECO:0000313|EMBL:AAI10831.1}; SubName: Full=Transcription factor p65 {ECO:0000313|Ensembl:ENSP00000432537};+++[Q96CP1_HUMAN|Unreviewed]SubName: Full=RELA protein {ECO:0000313|EMBL:AAH14095.1};+++[Q96F54_HUMAN|Unreviewed]SubName: Full=RELA protein {ECO:0000313|EMBL:AAH11603.1};"]
[5979,"'RET'",19,18,16,17.6666666666667,"05230///Central carbon metabolism in cancer+++05200///Pathways in cancer+++05216///Thyroid cancer","H00822///Renal agenesis and Renal adysplasia+++H00032///Thyroid cancer+++H01510///Malignant paraganglioma+++H00910///Hirschsprung disease (HD)+++H00916///Congenital central hypoventilation syndrome (CCHS)+++H00247///Multiple endocrine neoplasia syndrome (MEN)+++H01592///Medullary thyroid cancer",null,null,"GO:0030424///axon+++GO:0043235///receptor complex+++GO:0030425///dendrite+++GO:0098797///plasma membrane protein complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0043025///neuronal cell body+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005768///endosome+++GO:0045121///membrane raft+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0010008///endosome membrane","GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0038023///signaling receptor activity+++GO:0000166///nucleotide binding","GO:0048265///response to pain+++GO:0007165///signal transduction+++GO:0072300///positive regulation of metanephric glomerulus development+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0048484///enteric nervous system development+++GO:0010628///positive regulation of gene expression+++GO:0000187///activation of MAPK activity+++GO:0006468///protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001657///ureteric bud development+++GO:0014042///positive regulation of neuron maturation+++GO:0033619///membrane protein proteolysis+++GO:0035799///ureter maturation+++GO:0042493///response to drug+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0000165///MAPK cascade+++GO:0001838///embryonic epithelial tube formation+++GO:0007158///neuron cell-cell adhesion+++GO:0016310///phosphorylation+++GO:0007155///cell adhesion+++GO:0045793///positive regulation of cell size+++GO:0007399///nervous system development+++GO:0043066///negative regulation of apoptotic process+++GO:0061146///Peyer's patch morphogenesis+++GO:0060384///innervation+++GO:0042551///neuron maturation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0030335///positive regulation of cell migration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0007497///posterior midgut development+++GO:0001755///neural crest cell migration+++GO:0050770///regulation of axonogenesis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097021///lymphocyte migration into lymphoid organs+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0043410///positive regulation of MAPK cascade+++GO:0071300///cellular response to retinoic acid+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway+++GO:0030155///regulation of cell adhesion+++GO:0060041///retina development in camera-type eye+++GO:0010976///positive regulation of neuron projection development+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0007411///axon guidance+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0009968///negative regulation of signal transduction+++GO:0030182///neuron differentiation","ret proto-oncogene","[RET_HUMAN|Reviewed]RecName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000305}; EC=2.7.10.1; AltName: Full=Cadherin family member 12; AltName: Full=Proto-oncogene c-Ret; Contains: RecName: Full=Soluble RET kinase fragment; Contains: RecName: Full=Extracellular cell-membrane anchored RET cadherin 120 kDa fragment; Flags: Precursor;+++[A0A024R7S5_HUMAN|Unreviewed]SubName: Full=Ret proto-oncogene (Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease), isoform CRA_b {ECO:0000313|EMBL:EAW86583.1};+++[A0A024R7T1_HUMAN|Unreviewed]SubName: Full=Ret proto-oncogene (Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease), isoform CRA_a {ECO:0000313|EMBL:EAW86577.1};+++[A0A024R7T2_HUMAN|Unreviewed]RecName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000256|PIRNR:PIRNR000631}; EC=2.7.10.1 {ECO:0000256|PIRNR:PIRNR000631};+++[A0A1W2PPN7_HUMAN|Unreviewed]SubName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000313|Ensembl:ENSP00000491505}; Flags: Fragment;+++[A0A1W2PSA1_HUMAN|Unreviewed]SubName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000313|Ensembl:ENSP00000492728}; Flags: Fragment;+++[B4DGX8_HUMAN|Unreviewed]SubName: Full=Ret proto-oncogene (Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease), isoform CRA_c {ECO:0000313|EMBL:EAW86579.1}; SubName: Full=cDNA FLJ58503, highly similar to Proto-oncogene tyrosine-protein kinase receptorret {ECO:0000313|EMBL:BAG57939.1};+++[C9JYL6_HUMAN|Unreviewed]SubName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000313|Ensembl:ENSP00000419080}; Flags: Fragment;+++[F8TLS5_HUMAN|Unreviewed]RecName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000256|PIRNR:PIRNR000631}; EC=2.7.10.1 {ECO:0000256|PIRNR:PIRNR000631};+++[F8TLW0_HUMAN|Unreviewed]RecName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000256|PIRNR:PIRNR000631}; EC=2.7.10.1 {ECO:0000256|PIRNR:PIRNR000631};+++[L8EA94_HUMAN|Unreviewed]SubName: Full=Alternative protein RET {ECO:0000313|EMBL:CCQ43661.1};+++[M9Z0T2_HUMAN|Unreviewed]SubName: Full=Ret proto-oncoprotein {ECO:0000313|EMBL:AGK27784.1}; Flags: Fragment;+++[O43519_HUMAN|Unreviewed]SubName: Full=RET proto-oncogene {ECO:0000313|EMBL:AAB97168.1}; Flags: Fragment;+++[Q8IZR8_HUMAN|Unreviewed]SubName: Full=Ret proto-oncogene {ECO:0000313|EMBL:AAM77275.1}; Flags: Fragment;+++[Q8NFE8_HUMAN|Unreviewed]SubName: Full=Ret proto-oncogene {ECO:0000313|EMBL:AAM77279.1}; Flags: Fragment;+++[Q99886_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine kinase {ECO:0000313|EMBL:AAB47047.1}; Flags: Fragment;+++[Q9BTX6_HUMAN|Unreviewed]SubName: Full=Proto-oncogene tyrosine-protein kinase receptor Ret {ECO:0000313|Ensembl:ENSP00000480088}; SubName: Full=RET protein {ECO:0000313|EMBL:AAH03072.1};+++[Q9UE13_HUMAN|Unreviewed]SubName: Full=RET proto-oncogene tyrosine kinase receptor {ECO:0000313|EMBL:CAA75753.1}; SubName: Full=Ret proto-oncogene {ECO:0000313|EMBL:AAM77283.1}; Flags: Fragment;+++[Q9UM84_HUMAN|Unreviewed]SubName: Full=RET-ELE1 protein {ECO:0000313|EMBL:AAD14423.1}; Flags: Fragment;+++[Q9UM90_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine kinase {ECO:0000313|EMBL:AAB47046.1}; Flags: Fragment;+++[Q9UMQ4_HUMAN|Unreviewed]SubName: Full=RET tyrosine kinase receptor {ECO:0000313|EMBL:CAB46483.1}; Flags: Fragment;"]
[599,"'BCL2L2'",180.52,170.4,190,180.306666666667,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0097136///Bcl-2 family protein complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0031966///mitochondrial membrane+++GO:0005739///mitochondrion","GO:0097718///disordered domain specific binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0051400///BH domain binding+++GO:0046982///protein heterodimerization activity","GO:0042981///regulation of apoptotic process+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0006915///apoptotic process+++GO:0007283///spermatogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0060011///Sertoli cell proliferation","BCL2 like 2","[B2CL2_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[G3V3B7_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 2 {ECO:0000313|Ensembl:ENSP00000451148}; Flags: Fragment;+++[G3V3G8_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 2 {ECO:0000313|Ensembl:ENSP00000451234}; Flags: Fragment;+++[G3V4B7_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 2 {ECO:0000313|Ensembl:ENSP00000451701}; Flags: Fragment;+++[G3V5A9_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 2 {ECO:0000313|Ensembl:ENSP00000452265}; Flags: Fragment;+++[H0YJC7_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 2 {ECO:0000313|Ensembl:ENSP00000451197}; Flags: Fragment;"]
[6017,"'RLBP1'",547,893,812,750.666666666667,null,"H01009///Newfoundland rod-cone dystrophy (NFRCD)+++H00527///Retinitis pigmentosa (RP)+++H00825///Familial flecked retina syndrome",null,null,"GO:0005575///cellular_component+++GO:0044297///cell body+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005502///11-cis retinal binding+++GO:0019841///retinol binding+++GO:0016918///retinal binding","GO:0007601///visual perception+++GO:0050896///response to stimulus+++GO:0006776///vitamin A metabolic process+++GO:0001523///retinoid metabolic process","retinaldehyde binding protein 1","[RLBP1_HUMAN|Reviewed]RecName: Full=Retinaldehyde-binding protein 1; AltName: Full=Cellular retinaldehyde-binding protein;+++[H3BN92_HUMAN|Unreviewed]SubName: Full=Retinaldehyde-binding protein 1 {ECO:0000313|Ensembl:ENSP00000454740}; Flags: Fragment;+++[H3BTN3_HUMAN|Unreviewed]SubName: Full=Retinaldehyde-binding protein 1 {ECO:0000313|Ensembl:ENSP00000457251};"]
[6041,"'RNASEL'",180,249,172,200.333333333333,"05164///Influenza A+++05168///Herpes simplex infection+++04621///NOD-like receptor signaling pathway+++05160///Hepatitis C",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0016363///nuclear matrix+++GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004540///ribonuclease activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0016787///hydrolase activity+++GO:0019843///rRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding","GO:0060338///regulation of type I interferon-mediated signaling pathway+++GO:0006468///protein phosphorylation+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0043488///regulation of mRNA stability+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0045071///negative regulation of viral genome replication+++GO:0045444///fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006397///mRNA processing+++GO:0046326///positive regulation of glucose import+++GO:0006364///rRNA processing","ribonuclease L","[RN5A_HUMAN|Reviewed]RecName: Full=2-5A-dependent ribonuclease; Short=2-5A-dependent RNase; EC=3.1.26.-; AltName: Full=Ribonuclease 4; AltName: Full=Ribonuclease L; Short=RNase L;+++[Q1RLL8_HUMAN|Unreviewed]SubName: Full=Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) {ECO:0000313|EMBL:AAI15698.1};"]
[60487,"'TRMT11'",79,56,72,69,{"$nulls":5},"GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0004809///tRNA (guanine-N2-)-methyltransferase activity+++GO:0000049///tRNA binding+++GO:0016740///transferase activity","GO:0032259///methylation+++GO:0008033///tRNA processing+++GO:0030488///tRNA methylation","tRNA methyltransferase 11 homolog","[TRM11_HUMAN|Reviewed]RecName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog; EC=2.1.1.-; AltName: Full=tRNA guanosine-2'-O-methyltransferase TRM11 homolog;+++[K7EJQ4_HUMAN|Unreviewed]SubName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000313|Ensembl:ENSP00000465275}; Flags: Fragment;+++[K7ENP1_HUMAN|Unreviewed]SubName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000313|Ensembl:ENSP00000467035};+++[K7EPZ4_HUMAN|Unreviewed]SubName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000313|Ensembl:ENSP00000467603};+++[Q5JY01_HUMAN|Unreviewed]SubName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000313|Ensembl:ENSP00000406230}; Flags: Fragment;+++[Q5JY02_HUMAN|Unreviewed]SubName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000313|Ensembl:ENSP00000415724}; Flags: Fragment;+++[V9GXZ6_HUMAN|Unreviewed]SubName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000313|Ensembl:ENSP00000466001}; Flags: Fragment;"]
[60559,"'SPCS3'",721,592,681.04,664.68,"03060///Protein export",{"$nulls":3},"GO:0016020///membrane+++GO:0005787///signal peptidase complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0031090///organelle membrane+++GO:0005783///endoplasmic reticulum","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity","GO:0045047///protein targeting to ER+++GO:0006508///proteolysis+++GO:0006465///signal peptide processing","signal peptidase complex subunit 3","[SPCS3_HUMAN|Reviewed]RecName: Full=Signal peptidase complex subunit 3; EC=3.4.-.- {ECO:0000250|UniProtKB:P61008}; AltName: Full=Microsomal signal peptidase 22/23 kDa subunit; Short=SPC22/23; Short=SPase 22/23 kDa subunit;+++[D3DP46_HUMAN|Unreviewed]RecName: Full=Signal peptidase complex subunit 3 {ECO:0000256|PIRNR:PIRNR016089}; EC=3.4.-.- {ECO:0000256|PIRNR:PIRNR016089};"]
[60678,"'EEFSEC'",358,473,405,412,{"$nulls":4},"GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0003746///translation elongation factor activity+++GO:0035368///selenocysteine insertion sequence binding+++GO:0000049///tRNA binding","GO:0001514///selenocysteine incorporation+++GO:0006412///translation+++GO:0006414///translational elongation","eukaryotic elongation factor, selenocysteine-tRNA specific","[SELB_HUMAN|Reviewed]RecName: Full=Selenocysteine-specific elongation factor; AltName: Full=Elongation factor sec; AltName: Full=Eukaryotic elongation factor, selenocysteine-tRNA-specific;+++[C9J8T0_HUMAN|Unreviewed]SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|Ensembl:ENSP00000417660};"]
[6101,"'RP1'",4,2,2,2.66666666666667,null,"H01010///Occult macular dystrophy (OMD)+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0001917///photoreceptor inner segment+++GO:0097542///ciliary tip+++GO:0001750///photoreceptor outer segment+++GO:0032391///photoreceptor connecting cilium+++GO:0005787///signal peptidase complex+++GO:0005930///axoneme+++GO:0005875///microtubule associated complex+++GO:0016021///integral component of membrane+++GO:0005874///microtubule","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0008017///microtubule binding","GO:0042461///photoreceptor cell development+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0046548///retinal rod cell development+++GO:0035082///axoneme assembly+++GO:0007603///phototransduction, visible light+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006465///signal peptide processing+++GO:0071482///cellular response to light stimulus+++GO:0045494///photoreceptor cell maintenance+++GO:0035845///photoreceptor cell outer segment organization+++GO:0007601///visual perception+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0046549///retinal cone cell development+++GO:0035556///intracellular signal transduction+++GO:0060041///retina development in camera-type eye","RP1, axonemal microtubule associated","[RP1_HUMAN|Reviewed]RecName: Full=Oxygen-regulated protein 1; AltName: Full=Retinitis pigmentosa 1 protein; AltName: Full=Retinitis pigmentosa RP1 protein;"]
[6130,"'RPL7A'",12185,12319,11353,11952.3333333333,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0022625///cytosolic large ribosomal subunit+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0005840///ribosome+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0042788///polysomal ribosome+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0042254///ribosome biogenesis+++GO:0000470///maturation of LSU-rRNA","ribosomal protein L7a","[RL7A_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L7a; AltName: Full=Large ribosomal subunit protein eL8 {ECO:0000303|PubMed:24524803}; AltName: Full=PLA-X polypeptide; AltName: Full=Surfeit locus protein 3;+++[Q5T8U2_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L7a {ECO:0000313|Ensembl:ENSP00000361071}; SubName: Full=Ribosomal protein L7a {ECO:0000313|EMBL:CAI12834.1};+++[Q5T8U3_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L7a {ECO:0000313|Ensembl:ENSP00000416638}; SubName: Full=Ribosomal protein L7a {ECO:0000313|EMBL:CAI12833.1}; Flags: Fragment;"]
[6147,"'RPL23A'",9065,9773,9030,9289.33333333333,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005840///ribosome+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0022625///cytosolic large ribosomal subunit","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0070180///large ribosomal subunit rRNA binding+++GO:1904841///TORC2 complex binding+++GO:0019843///rRNA binding+++GO:0045296///cadherin binding","GO:0000027///ribosomal large subunit assembly+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0008283///cell proliferation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","ribosomal protein L23a","[RL23A_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L23a; AltName: Full=Large ribosomal subunit protein uL23 {ECO:0000303|PubMed:24524803};+++[A8MUS3_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L23a {ECO:0000313|Ensembl:ENSP00000378396}; SubName: Full=Ribosomal protein L23a, isoform CRA_a {ECO:0000313|EMBL:EAW51131.1};+++[H7BY10_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L23a {ECO:0000313|Ensembl:ENSP00000347969}; Flags: Fragment;+++[K7EJV9_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L23a {ECO:0000313|Ensembl:ENSP00000465342}; Flags: Fragment;+++[K7EMA7_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L23a {ECO:0000313|Ensembl:ENSP00000466425};+++[K7ERT8_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L23a {ECO:0000313|Ensembl:ENSP00000468402}; Flags: Fragment;"]
[6169,"'RPL38'",2648,2957,2566,2723.66666666667,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0045202///synapse+++GO:0005840///ribosome+++GO:0042788///polysomal ribosome+++GO:0014069///postsynaptic density+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit+++GO:0033291///eukaryotic 80S initiation complex","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0001501///skeletal system development+++GO:0006417///regulation of translation+++GO:0006412///translation+++GO:0034463///90S preribosome assembly+++GO:0006413///translational initiation+++GO:0002181///cytoplasmic translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0042474///middle ear morphogenesis+++GO:0048318///axial mesoderm development+++GO:0001503///ossification+++GO:0007605///sensory perception of sound","ribosomal protein L38","[RL38_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L38; AltName: Full=Large ribosomal subunit protein eL38 {ECO:0000303|PubMed:24524803};+++[A0A024R8P8_HUMAN|Unreviewed]SubName: Full=Ribosomal protein L38, isoform CRA_a {ECO:0000313|EMBL:EAW89140.1};+++[J3KSP2_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L38 {ECO:0000313|Ensembl:ENSP00000462580}; Flags: Fragment;+++[J3KT73_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L38 {ECO:0000313|Ensembl:ENSP00000462837};+++[J3QL01_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L38 {ECO:0000313|Ensembl:ENSP00000463312};"]
[6192,"'RPS4Y1'",2248,2363,2150,2253.66666666667,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0016020///membrane+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding","GO:0006412///translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0007275///multicellular organism development+++GO:0006413///translational initiation","ribosomal protein S4 Y-linked 1","[RS4Y1_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S4, Y isoform 1; AltName: Full=Small ribosomal subunit protein eS4 {ECO:0000303|PubMed:24524803};+++[A4FU11_HUMAN|Unreviewed]SubName: Full=RPS4Y1 protein {ECO:0000313|EMBL:AAI00907.1}; Flags: Fragment;+++[C9JEH7_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S4, Y isoform 1 {ECO:0000313|Ensembl:ENSP00000415317}; Flags: Fragment;+++[Q496E4_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein S4 {ECO:0000256|PIRNR:PIRNR002116};"]
[6205,"'RPS11'",16131,17471,15907,16503,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0005730///nucleolus+++GO:0005840///ribosome+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0022627///cytosolic small ribosomal subunit","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0019843///rRNA binding","GO:0006413///translational initiation+++GO:0006412///translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","ribosomal protein S11","[RS11_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S11; AltName: Full=Small ribosomal subunit protein uS17 {ECO:0000303|PubMed:24524803};+++[M0QZ90_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S11 {ECO:0000313|Ensembl:ENSP00000470375}; Flags: Fragment;+++[M0QZC5_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S11 {ECO:0000313|Ensembl:ENSP00000470447};+++[M0R1H5_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S11 {ECO:0000313|Ensembl:ENSP00000471873};+++[M0R1H6_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S11 {ECO:0000313|Ensembl:ENSP00000471874};"]
[623,"'BDKRB1'",4,2,5,3.66666666666667,"04750///Inflammatory mediator regulation of TRP channels+++04810///Regulation of actin cytoskeleton+++04080///Neuroactive ligand-receptor interaction+++04020///Calcium signaling pathway+++04610///Complement and coagulation cascades+++05200///Pathways in cancer",{"$nulls":3},"GO:0005768///endosome+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043005///neuron projection","GO:0004947///bradykinin receptor activity+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0046982///protein heterodimerization activity+++GO:0031702///type 1 angiotensin receptor binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0002020///protease binding+++GO:0042277///peptide binding","GO:0001933///negative regulation of protein phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0009651///response to salt stress+++GO:0009612///response to mechanical stimulus+++GO:0002687///positive regulation of leukocyte migration+++GO:0043114///regulation of vascular permeability+++GO:0006954///inflammatory response+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0042311///vasodilation+++GO:0045776///negative regulation of blood pressure+++GO:0007165///signal transduction+++GO:0032496///response to lipopolysaccharide+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0019233///sensory perception of pain+++GO:0030308///negative regulation of cell growth+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0007166///cell surface receptor signaling pathway+++GO:0050482///arachidonic acid secretion+++GO:0042310///vasoconstriction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:1902219///negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:0019229///regulation of vasoconstriction+++GO:0016477///cell migration+++GO:0008015///blood circulation+++GO:1902239///negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006939///smooth muscle contraction","bradykinin receptor B1","[BKRB1_HUMAN|Reviewed]RecName: Full=B1 bradykinin receptor; Short=B1R; Short=BK-1 receptor;+++[G3V4Y2_HUMAN|Unreviewed]SubName: Full=B1 bradykinin receptor {ECO:0000313|Ensembl:ENSP00000452064};"]
[6252,"'RTN1'",20,39,34,31,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0030182///neuron differentiation","reticulon 1","[RTN1_HUMAN|Reviewed]RecName: Full=Reticulon-1; AltName: Full=Neuroendocrine-specific protein;+++[A8K3B9_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[A8MT72_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[Q2L7A7_HUMAN|Unreviewed]SubName: Full=Reticulon 1 isoform A {ECO:0000313|EMBL:ABC71342.1}; Flags: Fragment;+++[Q2NKQ5_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[Q6IAX4_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};"]
[6274,"'S100A3'",33,22,17,24,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0008270///zinc ion binding+++GO:0046914///transition metal ion binding",null,"S100 calcium binding protein A3","[S10A3_HUMAN|Reviewed]RecName: Full=Protein S100-A3; AltName: Full=Protein S-100E; AltName: Full=S100 calcium-binding protein A3;"]
[63027,"'SLC22A23'",443,480,475,466,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity+++GO:0005215///transporter activity","GO:0006811///ion transport+++GO:0055085///transmembrane transport","solute carrier family 22 member 23","[S22AN_HUMAN|Reviewed]RecName: Full=Solute carrier family 22 member 23;+++[C9IZW5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000418985}; Flags: Fragment;+++[C9J4Z0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000410245};+++[F8WBC7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000417737};+++[H7C4T9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000418134}; Flags: Fragment;+++[Q7L9D0_HUMAN|Unreviewed]SubName: Full=SLC22A23 protein {ECO:0000313|EMBL:AAH22217.1}; SubName: Full=cDNA: FLJ21380 fis, clone COL03329 {ECO:0000313|EMBL:BAB15054.1}; SubName: Full=cDNA: FLJ22174 fis, clone HRC00767 {ECO:0000313|EMBL:BAB15250.1};+++[Q9UFY2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434F011 {ECO:0000313|EMBL:CAB53695.1}; Flags: Fragment;"]
[6319,"'SCD'",8215,9696,9762,9224.33333333333,"04152///AMPK signaling pathway+++01212///Fatty acid metabolism+++01040///Biosynthesis of unsaturated fatty acids+++03320///PPAR signaling pathway+++04212///Longevity regulating pathway - worm",null,null,"R02222///steroyl-CoA,hydrogen-donor:oxygen oxidoreductase   Stearoyl-CoA + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> Oleoyl-CoA + 2 Ferricytochrome b5 + 2 H2O","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0005506///iron ion binding+++GO:0016717///oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water+++GO:0016491///oxidoreductase activity+++GO:0004768///stearoyl-CoA 9-desaturase activity+++GO:0046872///metal ion binding+++GO:0032896///palmitoyl-CoA 9-desaturase activity","GO:0006629///lipid metabolic process+++GO:0006636///unsaturated fatty acid biosynthetic process+++GO:1903966///monounsaturated fatty acid biosynthetic process+++GO:0006633///fatty acid biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0070542///response to fatty acid+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0046949///fatty-acyl-CoA biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0045540///regulation of cholesterol biosynthetic process","stearoyl-CoA desaturase","[ACOD_HUMAN|Reviewed]RecName: Full=Acyl-CoA desaturase; EC=1.14.19.1 {ECO:0000269|PubMed:15610069, ECO:0000269|PubMed:15907797, ECO:0000269|PubMed:18765284}; AltName: Full=Delta(9)-desaturase; Short=Delta-9 desaturase; AltName: Full=Fatty acid desaturase; AltName: Full=Stearoyl-CoA desaturase {ECO:0000303|PubMed:18765284}; Short=hSCD1 {ECO:0000303|PubMed:15907797};"]
[6337,"'SCNN1A'",474,522,470,488.666666666667,"04742///Taste transduction+++04960///Aldosterone-regulated sodium reabsorption","H00892///Bronchiectasis with or without elevated sweat chloride+++H00243///Hyperkalemic distal renal tubular acidosis (RTA type 4)",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031514///motile cilium+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0060170///ciliary membrane+++GO:0034706///sodium channel complex+++GO:0005737///cytoplasm+++GO:0001669///acrosomal vesicle+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0097228///sperm principal piece+++GO:0005929///cilium","GO:0015280///ligand-gated sodium channel activity+++GO:0050699///WW domain binding+++GO:0005272///sodium channel activity+++GO:0005515///protein binding","GO:0006814///sodium ion transport+++GO:0050909///sensory perception of taste+++GO:0050891///multicellular organismal water homeostasis+++GO:0050896///response to stimulus+++GO:0006811///ion transport+++GO:0035725///sodium ion transmembrane transport+++GO:0055078///sodium ion homeostasis","sodium channel epithelial 1 alpha subunit","[SCNNA_HUMAN|Reviewed]RecName: Full=Amiloride-sensitive sodium channel subunit alpha; AltName: Full=Alpha-NaCH; AltName: Full=Epithelial Na(+) channel subunit alpha; Short=Alpha-ENaC; Short=ENaCA; AltName: Full=Nonvoltage-gated sodium channel 1 subunit alpha; AltName: Full=SCNEA;+++[C5HTY8_HUMAN|Unreviewed]SubName: Full=Amiloride-sensitive sodium channel subunit alpha 1 {ECO:0000313|EMBL:ACS13720.1};+++[C5HTY9_HUMAN|Unreviewed]SubName: Full=Amiloride-sensitive sodium channel subunit alpha {ECO:0000313|EMBL:ACS13719.1};+++[C5HTZ1_HUMAN|Unreviewed]SubName: Full=Amiloride-sensitive sodium channel subunit alpha 3 {ECO:0000313|EMBL:ACS13722.1};+++[F5GXE6_HUMAN|Unreviewed]SubName: Full=Amiloride-sensitive sodium channel subunit alpha {ECO:0000313|Ensembl:ENSP00000440876};+++[F5H5F8_HUMAN|Unreviewed]SubName: Full=Amiloride-sensitive sodium channel subunit alpha {ECO:0000313|Ensembl:ENSP00000443434}; Flags: Fragment;+++[J3KPV6_HUMAN|Unreviewed]SubName: Full=Amiloride-sensitive sodium channel subunit alpha {ECO:0000313|Ensembl:ENSP00000380166};+++[Q6UP09_HUMAN|Unreviewed]SubName: Full=Amiloride-sensitive epithelial sodium channel alpha subunit {ECO:0000313|EMBL:AAQ67341.1}; Flags: Fragment;"]
[6342,"'SCP2'",662,644,617,641,"03320///PPAR signaling pathway+++00120///Primary bile acid biosynthesis+++01100///Metabolic pathways+++04146///Peroxisome","H00874///Leukoencephalopathy with dystonia and motor neuropathy+++H00407///Peroxisomal beta-oxidation enzyme deficiency","M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R04811///Propanoyl-CoA:acetyl-CoA C-acyltransferase; 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA; C-acyltransferase   Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA+++R03719///3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase; choloyl-CoA:propanoyl-CoA   Propanoyl-CoA + Choloyl-CoA <=> CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA","GO:0005782///peroxisomal matrix+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005777///peroxisome+++GO:0032991///protein-containing complex+++GO:0005739///mitochondrion","GO:0050632///propionyl-CoA C2-trimethyltridecanoyltransferase activity+++GO:0008526///phosphatidylinositol transporter activity+++GO:0070538///oleic acid binding+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0000062///fatty-acyl-CoA binding+++GO:0033814///propanoyl-CoA C-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0015248///sterol transporter activity+++GO:0005102///signaling receptor binding","GO:0006625///protein targeting to peroxisome+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0032385///positive regulation of intracellular cholesterol transport+++GO:0036109///alpha-linolenic acid metabolic process+++GO:1901373///lipid hydroperoxide transport+++GO:0006694///steroid biosynthetic process+++GO:0015914///phospholipid transport+++GO:0006701///progesterone biosynthetic process+++GO:0006699///bile acid biosynthetic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0045940///positive regulation of steroid metabolic process+++GO:0072659///protein localization to plasma membrane","sterol carrier protein 2","[NLTP_HUMAN|Reviewed]RecName: Full=Non-specific lipid-transfer protein; Short=NSL-TP; EC=2.3.1.176; AltName: Full=Propanoyl-CoA C-acyltransferase; AltName: Full=SCP-chi; AltName: Full=SCPX; AltName: Full=Sterol carrier protein 2; Short=SCP-2; AltName: Full=Sterol carrier protein X; Short=SCP-X;+++[B2R761_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93299, highly similar to Homo sapiens sterol carrier protein 2 (SCP2), mRNA {ECO:0000313|EMBL:BAG35708.1};+++[E9PLD1_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000435194};+++[Q59HG9_HUMAN|Unreviewed]SubName: Full=Sterol carrier protein X isoform 1 proprotein variant {ECO:0000313|EMBL:BAD92026.1}; Flags: Fragment;"]
[63876,"'PKNOX2'",1259,1495,1288,1347.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0045171///intercellular bridge+++GO:0015630///microtubule cytoskeleton+++GO:0005654///nucleoplasm+++GO:0015629///actin cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0043565///sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003785///actin monomer binding+++GO:0051015///actin filament binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","PBX/knotted 1 homeobox 2","[PKNX2_HUMAN|Reviewed]RecName: Full=Homeobox protein PKNOX2; AltName: Full=Homeobox protein PREP-2; AltName: Full=PBX/knotted homeobox 2;+++[E9PKL2_HUMAN|Unreviewed]SubName: Full=Homeobox protein PKNOX2 {ECO:0000313|Ensembl:ENSP00000431599}; Flags: Fragment;+++[E9PQS4_HUMAN|Unreviewed]SubName: Full=Homeobox protein PKNOX2 {ECO:0000313|Ensembl:ENSP00000434377};+++[E9PRB6_HUMAN|Unreviewed]SubName: Full=Homeobox protein PKNOX2 {ECO:0000313|Ensembl:ENSP00000434255}; Flags: Fragment;+++[H0YLX0_HUMAN|Unreviewed]SubName: Full=Homeobox protein PKNOX2 {ECO:0000313|Ensembl:ENSP00000453374}; Flags: Fragment;"]
[63894,"'VIPAS39'",644,683,618,648.333333333333,{"$nulls":4},"GO:0055037///recycling endosome+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0030897///HOPS complex","GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0017185///peptidyl-lysine hydroxylation+++GO:0097352///autophagosome maturation+++GO:0030154///cell differentiation+++GO:0032963///collagen metabolic process+++GO:0030199///collagen fibril organization+++GO:0007283///spermatogenesis+++GO:0015031///protein transport+++GO:0008333///endosome to lysosome transport+++GO:0006886///intracellular protein transport+++GO:0043687///post-translational protein modification","VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog","[SPE39_HUMAN|Reviewed]RecName: Full=Spermatogenesis-defective protein 39 homolog; Short=hSPE-39; AltName: Full=VPS33B-interacting protein in apical-basolateral polarity regulator; AltName: Full=VPS33B-interacting protein in polarity and apical restriction;+++[B4DMB7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55986 {ECO:0000313|EMBL:BAG59829.1};+++[G3V4K3_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-defective protein 39 homolog {ECO:0000313|Ensembl:ENSP00000451857};+++[G3V549_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-defective protein 39 homolog {ECO:0000313|Ensembl:ENSP00000452176}; Flags: Fragment;+++[Q6IA61_HUMAN|Unreviewed]SubName: Full=C14orf133 protein {ECO:0000313|EMBL:CAG33575.1}; SubName: Full=Chromosome 14 open reading frame 133, isoform CRA_a {ECO:0000313|EMBL:EAW81286.1}; SubName: Full=cDNA FLJ40935 fis, clone UTERU2007253 {ECO:0000313|EMBL:BAG53601.1};"]
[63932,"'CXorf56'",184,163,137,161.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0005634///nucleus",null,null,"chromosome X open reading frame 56","[CX056_HUMAN|Reviewed]RecName: Full=UPF0428 protein CXorf56;"]
[63976,"'PRDM16'",3264,4431,3608,3767.66666666667,"04714///Thermogenesis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0017053///transcriptional repressor complex+++GO:0016235///aggresome","GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0046332///SMAD binding+++GO:0033613///activating transcription factor binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0034968///histone lysine methylation+++GO:0060021///roof of mouth development+++GO:0022008///neurogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0050872///white fat cell differentiation+++GO:0043586///tongue development+++GO:0035019///somatic stem cell population maintenance+++GO:0090336///positive regulation of brown fat cell differentiation+++GO:0019827///stem cell population maintenance+++GO:0050873///brown fat cell differentiation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043457///regulation of cellular respiration","PR/SET domain 16","[PRD16_HUMAN|Reviewed]RecName: Full=PR domain zinc finger protein 16 {ECO:0000305}; AltName: Full=PR domain-containing protein 16 {ECO:0000305}; AltName: Full=Transcription factor MEL1 {ECO:0000305}; Short=MDS1/EVI1-like gene 1 {ECO:0000303|PubMed:11050005};+++[D6RDW0_HUMAN|Unreviewed]SubName: Full=PR domain zinc finger protein 16 {ECO:0000313|Ensembl:ENSP00000426975};+++[D6RFY3_HUMAN|Unreviewed]SubName: Full=PR domain zinc finger protein 16 {ECO:0000313|Ensembl:ENSP00000421400};+++[H0YA13_HUMAN|Unreviewed]SubName: Full=PR domain zinc finger protein 16 {ECO:0000313|Ensembl:ENSP00000425796}; Flags: Fragment;+++[L8E8P9_HUMAN|Unreviewed]SubName: Full=Alternative protein PRDM16 {ECO:0000313|EMBL:CCQ43680.1};+++[U3KQL6_HUMAN|Unreviewed]SubName: Full=PR domain zinc finger protein 16 {ECO:0000313|Ensembl:ENSP00000476002}; Flags: Fragment;"]
[6405,"'SEMA3F'",3105,3225,3215.84,3181.94666666667,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0098978///glutamatergic synapse+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane","GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity","GO:0097490///sympathetic neuron projection extension+++GO:0021675///nerve development+++GO:0061549///sympathetic ganglion development+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0021612///facial nerve structural organization+++GO:0099175///regulation of postsynapse organization+++GO:0021785///branchiomotor neuron axon guidance+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0021637///trigeminal nerve structural organization+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:0030335///positive regulation of cell migration+++GO:0048846///axon extension involved in axon guidance+++GO:0097491///sympathetic neuron projection guidance+++GO:0036486///ventral trunk neural crest cell migration+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:0007411///axon guidance","semaphorin 3F","[SEM3F_HUMAN|Reviewed]RecName: Full=Semaphorin-3F; AltName: Full=Sema III/F; AltName: Full=Semaphorin IV; Short=Sema IV; Flags: Precursor;+++[C9IYS6_HUMAN|Unreviewed]SubName: Full=Semaphorin-3F {ECO:0000313|Ensembl:ENSP00000400549}; Flags: Fragment;+++[C9J1V2_HUMAN|Unreviewed]SubName: Full=Semaphorin-3F {ECO:0000313|Ensembl:ENSP00000392588}; Flags: Fragment;+++[C9J4H5_HUMAN|Unreviewed]SubName: Full=Semaphorin-3F {ECO:0000313|Ensembl:ENSP00000398399}; Flags: Fragment;+++[C9JPG5_HUMAN|Unreviewed]SubName: Full=Semaphorin-3F {ECO:0000313|Ensembl:ENSP00000388931};+++[H7C4A2_HUMAN|Unreviewed]SubName: Full=Semaphorin-3F {ECO:0000313|Ensembl:ENSP00000416356}; Flags: Fragment;+++[Q59G50_HUMAN|Unreviewed]SubName: Full=Semaphorin 3F variant {ECO:0000313|EMBL:BAD92496.1}; Flags: Fragment;"]
[64098,"'PARVG'",73,109.21,94.03,92.08,"04510///Focal adhesion",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0015629///actin cytoskeleton+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0003779///actin binding","GO:0007163///establishment or maintenance of cell polarity+++GO:0031532///actin cytoskeleton reorganization+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0030031///cell projection assembly+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion","parvin gamma","[PARVG_HUMAN|Reviewed]RecName: Full=Gamma-parvin;+++[A0A024R4U4_HUMAN|Unreviewed]SubName: Full=Parvin, gamma, isoform CRA_b {ECO:0000313|EMBL:EAW73336.1};+++[B0QYM9_HUMAN|Unreviewed]SubName: Full=Gamma-parvin {ECO:0000313|Ensembl:ENSP00000399839}; Flags: Fragment;+++[B0QYN0_HUMAN|Unreviewed]SubName: Full=Gamma-parvin {ECO:0000313|Ensembl:ENSP00000407199}; Flags: Fragment;+++[U3KQ67_HUMAN|Unreviewed]SubName: Full=Gamma-parvin {ECO:0000313|Ensembl:ENSP00000475593};"]
[64115,"'VSIR'",1663,1354,1387,1468,null,"H01705///Bilateral sudden sensorineural hearing loss+++H00779///Usher syndrome (US)+++H00605///Deafness, autosomal recessive",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding+++GO:0061133///endopeptidase activator activity+++GO:0019899///enzyme binding","GO:0032689///negative regulation of interferon-gamma production+++GO:0120158///positive regulation of collagen catabolic process+++GO:0030335///positive regulation of cell migration+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0031638///zymogen activation+++GO:2000565///negative regulation of CD8-positive, alpha-beta T cell proliferation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0010950///positive regulation of endopeptidase activity+++GO:0045591///positive regulation of regulatory T cell differentiation","V-set immunoregulatory receptor","[VISTA_HUMAN|Reviewed]RecName: Full=V-type immunoglobulin domain-containing suppressor of T-cell activation {ECO:0000303|PubMed:24691993}; AltName: Full=Platelet receptor Gi24 {ECO:0000303|Ref.1}; AltName: Full=Stress-induced secreted protein-1 {ECO:0000303|Ref.2}; Short=Sisp-1 {ECO:0000303|Ref.2}; AltName: Full=V-set domain-containing immunoregulatory receptor {ECO:0000250|UniProtKB:Q9D659}; AltName: Full=V-set immunoregulatory receptor {ECO:0000312|HGNC:HGNC:30085}; Flags: Precursor;+++[Q2TA85_HUMAN|Unreviewed]SubName: Full=C10orf54 protein {ECO:0000313|EMBL:AAI11049.1}; Flags: Fragment;+++[Q8WYG9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PP2135 {ECO:0000313|EMBL:AAG22476.1};"]
[64130,"'LIN7B'",40,38,38,38.6666666666667,{"$nulls":4},"GO:0030054///cell junction+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0016020///membrane+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0016323///basolateral plasma membrane+++GO:0005923///bicellular tight junction+++GO:0098793///presynapse+++GO:0005911///cell-cell junction+++GO:0045202///synapse+++GO:0043005///neuron projection","GO:0097016///L27 domain binding+++GO:0019904///protein domain specific binding+++GO:0030165///PDZ domain binding","GO:0015031///protein transport+++GO:1903361///protein localization to basolateral plasma membrane+++GO:0007269///neurotransmitter secretion+++GO:0006887///exocytosis","lin-7 homolog B, crumbs cell polarity complex component","[LIN7B_HUMAN|Reviewed]RecName: Full=Protein lin-7 homolog B; Short=Lin-7B; Short=hLin7B; AltName: Full=Mammalian lin-seven protein 2; Short=MALS-2; AltName: Full=Vertebrate lin-7 homolog 2; Short=Veli-2; Short=hVeli2;+++[M0R2U1_HUMAN|Unreviewed]SubName: Full=Protein lin-7 homolog B {ECO:0000313|Ensembl:ENSP00000472804}; Flags: Fragment;+++[S4R3R4_HUMAN|Unreviewed]SubName: Full=Protein lin-7 homolog B {ECO:0000313|Ensembl:ENSP00000474643}; Flags: Fragment;"]
[6416,"'MAP2K4'",598,573,485,552,"04668///TNF signaling pathway+++04620///Toll-like receptor signaling pathway+++04013///MAPK signaling pathway - fly+++05166///HTLV-I infection+++04664///Fc epsilon RI signaling pathway+++05169///Epstein-Barr virus infection+++04010///MAPK signaling pathway+++05418///Fluid shear stress and atherosclerosis+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05164///Influenza A+++04912///GnRH signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05161///Hepatitis B+++04012///ErbB signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++04926///Relaxin signaling pathway",null,"M00688///MAPK (JNK) signaling",null,"GO:0032839///dendrite cytoplasm+++GO:0005737///cytoplasm+++GO:0043204///perikaryon+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0030424///axon","GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0004708///MAP kinase kinase activity+++GO:0005515///protein binding+++GO:0008545///JUN kinase kinase activity+++GO:0005524///ATP binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity","GO:0023014///signal transduction by protein phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0006915///apoptotic process+++GO:0072709///cellular response to sorbitol+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0009611///response to wounding+++GO:0006468///protein phosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0045740///positive regulation of DNA replication+++GO:0032147///activation of protein kinase activity+++GO:0007254///JNK cascade+++GO:0000165///MAPK cascade+++GO:2000672///negative regulation of motor neuron apoptotic process+++GO:0000187///activation of MAPK activity+++GO:0071260///cellular response to mechanical stimulus+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0007257///activation of JUN kinase activity","mitogen-activated protein kinase kinase 4","[MP2K4_HUMAN|Reviewed]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 4; Short=MAP kinase kinase 4; Short=MAPKK 4; EC=2.7.12.2; AltName: Full=JNK-activating kinase 1; AltName: Full=MAPK/ERK kinase 4; Short=MEK 4; AltName: Full=SAPK/ERK kinase 1; Short=SEK1; AltName: Full=Stress-activated protein kinase kinase 1; Short=SAPK kinase 1; Short=SAPKK-1; Short=SAPKK1; AltName: Full=c-Jun N-terminal kinase kinase 1; Short=JNKK;+++[J3QLE2_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000463507};+++[K7EP58_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000467239}; Flags: Fragment;+++[R4GN37_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000473472};+++[R4GN68_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 4 {ECO:0000313|Ensembl:ENSP00000473511};"]
[6423,"'SFRP2'",86,71,165,107.333333333333,"04310///Wnt signaling pathway",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0001968///fibronectin binding+++GO:0008047///enzyme activator activity+++GO:0017147///Wnt-protein binding+++GO:0005178///integrin binding+++GO:0061133///endopeptidase activator activity+++GO:0048018///receptor ligand activity","GO:0030154///cell differentiation+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0071481///cellular response to X-ray+++GO:0043508///negative regulation of JUN kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031668///cellular response to extracellular stimulus+++GO:0009952///anterior/posterior pattern specification+++GO:0061056///sclerotome development+++GO:0090175///regulation of establishment of planar polarity+++GO:0010975///regulation of neuron projection development+++GO:0043065///positive regulation of apoptotic process+++GO:0046546///development of primary male sexual characteristics+++GO:0010950///positive regulation of endopeptidase activity+++GO:0071425///hematopoietic stem cell proliferation+++GO:0007584///response to nutrient+++GO:0030307///positive regulation of cell growth+++GO:0016055///Wnt signaling pathway+++GO:0036342///post-anal tail morphogenesis+++GO:0060028///convergent extension involved in axis elongation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010469///regulation of signaling receptor activity+++GO:2000041///negative regulation of planar cell polarity pathway involved in axis elongation+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042733///embryonic digit morphogenesis+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0003151///outflow tract morphogenesis+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0007275///multicellular organism development+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0060070///canonical Wnt signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:2000035///regulation of stem cell division+++GO:1904956///regulation of midbrain dopaminergic neuron differentiation+++GO:0008584///male gonad development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030336///negative regulation of cell migration+++GO:0002063///chondrocyte development+++GO:0030199///collagen fibril organization+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0042662///negative regulation of mesodermal cell fate specification+++GO:0030111///regulation of Wnt signaling pathway+++GO:0007267///cell-cell signaling+++GO:0021915///neural tube development+++GO:0001756///somitogenesis+++GO:0061185///negative regulation of dermatome development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0042493///response to drug+++GO:0010629///negative regulation of gene expression+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0001843///neural tube closure+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0090244///Wnt signaling pathway involved in somitogenesis+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0051216///cartilage development+++GO:0060349///bone morphogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0006915///apoptotic process+++GO:0048546///digestive tract morphogenesis","secreted frizzled related protein 2","[SFRP2_HUMAN|Reviewed]RecName: Full=Secreted frizzled-related protein 2; Short=FRP-2; Short=sFRP-2; AltName: Full=Secreted apoptosis-related protein 1; Short=SARP-1; Flags: Precursor;+++[A0A140VJU3_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 170 {ECO:0000313|EMBL:AEE61080.1};+++[B3KSM5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36603 fis, clone TRACH2015180, highly similar to Secreted frizzled-related protein 2 {ECO:0000313|EMBL:BAG52787.1};"]
[642517,"'AGAP9'",51.34,108.01,67.03,75.46,{"$nulls":4},"GO:0005634///nucleus","GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity","ArfGAP with GTPase domain, ankyrin repeat and PH domain 9","[AGAP9_HUMAN|Reviewed]RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 9; Short=AGAP-9; AltName: Full=Centaurin-gamma-like family member 6;"]
[643236,"'TMEM72'",144,183,179,168.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 72","[TMM72_HUMAN|Reviewed]RecName: Full=Transmembrane protein 72; AltName: Full=Kidney-specific secretory protein of 37 kDa;"]
[64327,"'LMBR1'",434,376,379,396.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005811///lipid droplet+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0000250///lanosterol synthase activity+++GO:0016853///isomerase activity+++GO:0016866///intramolecular transferase activity","GO:0006629///lipid metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0042733///embryonic digit morphogenesis+++GO:0031647///regulation of protein stability+++GO:0006694///steroid biosynthetic process+++GO:0045540///regulation of cholesterol biosynthetic process","limb development membrane protein 1","[LMBR1_HUMAN|Reviewed]RecName: Full=Limb region 1 protein homolog; AltName: Full=Differentiation-related gene 14 protein;+++[A0A0G2JQD0_HUMAN|Unreviewed]SubName: Full=Lanosterol synthase {ECO:0000313|Ensembl:ENSP00000485757}; Flags: Fragment;+++[A0A0G2JS81_HUMAN|Unreviewed]SubName: Full=Lanosterol synthase {ECO:0000313|Ensembl:ENSP00000487418}; Flags: Fragment;+++[A0A1W2PQV9_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000492304};+++[C9J315_HUMAN|Unreviewed]SubName: Full=Lanosterol synthase {ECO:0000313|Ensembl:ENSP00000391368}; Flags: Fragment;+++[F2Z2Z3_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000395754};+++[F8WB14_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000397698};+++[F8WCL1_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000392557};+++[F8WDW0_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000414795};+++[F8WEK4_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000413539};+++[F8WEN8_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000393928};+++[H0Y6V6_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000408256}; Flags: Fragment;+++[H7C1Y4_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000403052}; Flags: Fragment;+++[H7C3A5_HUMAN|Unreviewed]SubName: Full=Lanosterol synthase {ECO:0000313|Ensembl:ENSP00000410678}; Flags: Fragment;+++[Q7LDY5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C7orf2 {ECO:0000313|EMBL:AAS00382.1}; Flags: Fragment;+++[Q8NDP7_HUMAN|Unreviewed]SubName: Full=Limb region 1 protein homolog {ECO:0000313|Ensembl:ENSP00000352392};"]
[643596,"'RNF224'",13,5,8,8.66666666666667,"04928///Parathyroid hormone synthesis, secretion and action","H01298///Pulmonary alveolar microlithiasis (PALM)+++H02138///Hereditary hypophophatemic rickets with hypercalciuria+++H01198///Fanconi renotubular syndrome (FTS)+++H00214///Hypophosphatemic rickets+++H00888///Nephrolithiasis/osteoporosis, hypophosphatemic",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding","GO:0051865///protein autoubiquitination","ring finger protein 224","[RN224_HUMAN|Reviewed]RecName: Full=RING finger protein 224;"]
[643866,"'CBLN3'",20,22,25,22.3333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0005794///Golgi apparatus+++GO:0005615///extracellular space+++GO:0005576///extracellular region",null,null,"cerebellin 3 precursor","[CBLN3_HUMAN|Reviewed]RecName: Full=Cerebellin-3; Flags: Precursor;+++[G3V2Y8_HUMAN|Unreviewed]SubName: Full=Cerebellin-3 {ECO:0000313|Ensembl:ENSP00000450935}; SubName: Full=HCG40197 {ECO:0000313|EMBL:EAW66016.1};"]
[64409,"'GALNT17'",110,90,88,96,"00512///Mucin type O-glycan biosynthesis+++01100///Metabolic pathways","H01439///Williams-Beuren syndrome+++H01193///Familial tumoral calcinosis (FTC)+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane","GO:0046872///metal ion binding+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0030246///carbohydrate binding","GO:0006486///protein glycosylation","polypeptide N-acetylgalactosaminyltransferase 17","[GLT17_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 17 {ECO:0000305}; EC=2.4.1.41 {ECO:0000250|UniProtKB:Q9HCQ5}; AltName: Full=Polypeptide GalNAc transferase-like protein 3; Short=GalNAc-T-like protein 3; Short=pp-GaNTase-like protein 3; AltName: Full=Protein-UDP acetylgalactosaminyltransferase-like protein 3; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3; AltName: Full=Williams-Beuren syndrome chromosomal region 17 protein {ECO:0000303|PubMed:12073013, ECO:0000312|HGNC:HGNC:16347};+++[Q2L4S5_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[Q58A53_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};"]
[64420,"'SUSD1'",635,445,490,523.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding",null,"sushi domain containing 1","[SUSD1_HUMAN|Reviewed]RecName: Full=Sushi domain-containing protein 1; Flags: Precursor;+++[F8WAQ1_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000363381};+++[H0Y6B2_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000404269}; Flags: Fragment;+++[H0YCH6_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000431590}; Flags: Fragment;+++[H3BLV4_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000347558}; Flags: Fragment;"]
[6444,"'SGCD'",25,35,36,32,"05416///Viral myocarditis+++05414///Dilated cardiomyopathy (DCM)+++05410///Hypertrophic cardiomyopathy (HCM)+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)","H00294///Dilated cardiomyopathy (DCM)+++H00565///Sarcoglycanopathies+++H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005886///plasma membrane+++GO:0016011///dystroglycan complex+++GO:0005737///cytoplasm+++GO:0042383///sarcolemma+++GO:0016021///integral component of membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0016012///sarcoglycan complex","GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding","GO:0060048///cardiac muscle contraction+++GO:0048739///cardiac muscle fiber development+++GO:0019722///calcium-mediated signaling+++GO:0007517///muscle organ development+++GO:0086003///cardiac muscle cell contraction+++GO:0055074///calcium ion homeostasis+++GO:0034629///cellular protein-containing complex localization+++GO:0060977///coronary vasculature morphogenesis+++GO:0008219///cell death+++GO:0060047///heart contraction+++GO:0003015///heart process","sarcoglycan delta","[SGCD_HUMAN|Reviewed]RecName: Full=Delta-sarcoglycan; Short=Delta-SG; AltName: Full=35 kDa dystrophin-associated glycoprotein; Short=35DAG;+++[E5RI34_HUMAN|Unreviewed]SubName: Full=Delta-sarcoglycan {ECO:0000313|Ensembl:ENSP00000430794};"]
[64499,"'TPSB2'",4,2,3,3,{"$nulls":4},"GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0008236///serine-type peptidase activity+++GO:0005515///protein binding","GO:0006508///proteolysis","tryptase beta 2 (gene/pseudogene)","[TRYB2_HUMAN|Reviewed]RecName: Full=Tryptase beta-2; Short=Tryptase-2; EC=3.4.21.59; AltName: Full=Tryptase II; Flags: Precursor;+++[A0A087WUI4_HUMAN|Unreviewed]SubName: Full=Tryptase beta-2 {ECO:0000313|Ensembl:ENSP00000478695};+++[A0A087X1U0_HUMAN|Unreviewed]SubName: Full=Tryptase beta-2 {ECO:0000313|Ensembl:ENSP00000484461};+++[A0A140VJT7_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 163 {ECO:0000313|EMBL:AEE61074.1};+++[Q6FHB8_HUMAN|Unreviewed]SubName: Full=TPSB2 protein {ECO:0000313|EMBL:CAG46635.1}; Flags: Fragment;+++[Q6NZY1_HUMAN|Unreviewed]SubName: Full=TPSB2 protein {ECO:0000313|EMBL:AAH65923.1};+++[Q96RZ6_HUMAN|Unreviewed]SubName: Full=Tryptase I {ECO:0000313|EMBL:AAK61271.1};+++[Q96RZ7_HUMAN|Unreviewed]SubName: Full=Mast cell tryptase beta III {ECO:0000313|EMBL:AAK61270.1};"]
[6456,"'SH3GL2'",31,62,25,39.3333333333333,"04144///Endocytosis",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005769///early endosome+++GO:0045202///synapse+++GO:0030669///clathrin-coated endocytic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0097441///basal dendrite+++GO:0005737///cytoplasm+++GO:0099523///presynaptic cytosol+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0098684///photoreceptor ribbon synapse+++GO:0005886///plasma membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0005768///endosome+++GO:0043025///neuronal cell body+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098793///presynapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane","GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0008022///protein C-terminus binding","GO:0031175///neuron projection development+++GO:1903527///positive regulation of membrane tubulation+++GO:0007165///signal transduction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0006897///endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:0002090///regulation of receptor internalization+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0097484///dendrite extension+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0097753///membrane bending+++GO:0007417///central nervous system development+++GO:0099050///vesicle scission+++GO:0060988///lipid tube assembly+++GO:0097749///membrane tubulation+++GO:0061024///membrane organization+++GO:0048488///synaptic vesicle endocytosis","SH3 domain containing GRB2 like 2, endophilin A1","[SH3G2_HUMAN|Reviewed]RecName: Full=Endophilin-A1; AltName: Full=EEN-B1; AltName: Full=Endophilin-1; AltName: Full=SH3 domain protein 2A; AltName: Full=SH3 domain-containing GRB2-like protein 2;+++[A7LBA6_HUMAN|Unreviewed]SubName: Full=Endophilin {ECO:0000313|EMBL:ABS52637.1}; Flags: Fragment;+++[D3DRJ2_HUMAN|Unreviewed]SubName: Full=SH3-domain GRB2-like 2, isoform CRA_b {ECO:0000313|EMBL:EAW58663.1};+++[Q3V638_HUMAN|Unreviewed]SubName: Full=Mutated endophilin A1 BAR domain {ECO:0000313|EMBL:BAE44460.1};+++[Q3V639_HUMAN|Unreviewed]SubName: Full=Endophilin A1 BAR domain {ECO:0000313|EMBL:BAE44459.1};+++[Q7Z376_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686B23205 {ECO:0000313|EMBL:CAD97999.1}; Flags: Fragment;+++[Q8IZ09_HUMAN|Unreviewed]SubName: Full=SH3GL2 protein {ECO:0000313|EMBL:AAH32825.1};"]
[6464,"'SHC1'",3306,3402,3798,3502,"05225///Hepatocellular carcinoma+++04650///Natural killer cell mediated cytotoxicity+++05224///Breast cancer+++04012///ErbB signaling pathway+++04910///Insulin signaling pathway+++05226///Gastric cancer+++04917///Prolactin signaling pathway+++04072///Phospholipase D signaling pathway+++01522///Endocrine resistance+++05100///Bacterial invasion of epithelial cells+++04722///Neurotrophin signaling pathway+++05206///MicroRNAs in cancer+++04510///Focal adhesion+++05220///Chronic myeloid leukemia+++05034///Alcoholism+++04062///Chemokine signaling pathway+++05214///Glioma+++04013///MAPK signaling pathway - fly+++01521///EGFR tyrosine kinase inhibitor resistance+++04014///Ras signaling pathway+++04926///Relaxin signaling pathway+++04915///Estrogen signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0070435///Shc-EGFR complex+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0001784///phosphotyrosine residue binding+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0046875///ephrin receptor binding+++GO:0005158///insulin receptor binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0048408///epidermal growth factor binding+++GO:0005543///phospholipid binding","GO:0046579///positive regulation of Ras protein signal transduction+++GO:0038128///ERBB2 signaling pathway+++GO:0050900///leukocyte migration+++GO:0007507///heart development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0071363///cellular response to growth factor stimulus+++GO:0042127///regulation of cell proliferation+++GO:0016032///viral process+++GO:0098609///cell-cell adhesion+++GO:0042742///defense response to bacterium+++GO:0090322///regulation of superoxide metabolic process+++GO:0008286///insulin receptor signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0000187///activation of MAPK activity+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0000165///MAPK cascade+++GO:0007411///axon guidance+++GO:0040008///regulation of growth+++GO:0035556///intracellular signal transduction+++GO:0001525///angiogenesis+++GO:0031532///actin cytoskeleton reorganization+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0007176///regulation of epidermal growth factor-activated receptor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007265///Ras protein signal transduction+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0016525///negative regulation of angiogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043410///positive regulation of MAPK cascade+++GO:0007165///signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0038110///interleukin-2-mediated signaling pathway","SHC adaptor protein 1","[SHC1_HUMAN|Reviewed]RecName: Full=SHC-transforming protein 1; AltName: Full=SHC-transforming protein 3; AltName: Full=SHC-transforming protein A; AltName: Full=Src homology 2 domain-containing-transforming protein C1; Short=SH2 domain protein C1;+++[H0Y539_HUMAN|Unreviewed]SubName: Full=SHC-transforming protein 1 {ECO:0000313|Ensembl:ENSP00000396333}; Flags: Fragment;+++[Q5T181_HUMAN|Unreviewed]SubName: Full=SHC-transforming protein 1 {ECO:0000313|Ensembl:ENSP00000396162}; Flags: Fragment;+++[Q5T182_HUMAN|Unreviewed]SubName: Full=SHC-transforming protein 1 {ECO:0000313|Ensembl:ENSP00000398441}; Flags: Fragment;+++[Q5T187_HUMAN|Unreviewed]SubName: Full=SHC-transforming protein 1 {ECO:0000313|Ensembl:ENSP00000398864}; Flags: Fragment;+++[Q5T188_HUMAN|Unreviewed]SubName: Full=SHC-transforming protein 1 {ECO:0000313|Ensembl:ENSP00000404908}; Flags: Fragment;+++[X6R6D0_HUMAN|Unreviewed]SubName: Full=SHC-transforming protein 1 {ECO:0000313|Ensembl:ENSP00000357434};"]
[646960,"'PRSS56'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum","GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity","GO:0006508///proteolysis+++GO:0043010///camera-type eye development","serine protease 56","[PRS56_HUMAN|Reviewed]RecName: Full=Serine protease 56; EC=3.4.21.-; Flags: Precursor;+++[R4GMZ0_HUMAN|Unreviewed]SubName: Full=Serine protease 56 {ECO:0000313|Ensembl:ENSP00000473410};"]
[6472,"'SHMT2'",695,700,722,705.666666666667,"00630///Glyoxylate and dicarboxylate metabolism+++00260///Glycine, serine and threonine metabolism+++00670///One carbon pool by folate+++01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++00680///Methane metabolism+++01200///Carbon metabolism+++01523///Antifolate resistance+++01110///Biosynthesis of secondary metabolites+++00460///Cyanoamino acid metabolism+++01230///Biosynthesis of amino acids+++01130///Biosynthesis of antibiotics",null,"M00140///C1-unit interconversion, prokaryotes+++M00532///Photorespiration+++M00346///Formaldehyde assimilation, serine pathway+++M00141///C1-unit interconversion, eukaryotes","R09099///5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase   L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O+++R00945///5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase   5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine","GO:0005759///mitochondrial matrix+++GO:0070552///BRISC complex+++GO:0005634///nucleus+++GO:0042645///mitochondrial nucleoid+++GO:0005758///mitochondrial intermembrane space+++GO:0015630///microtubule cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0008168///methyltransferase activity+++GO:0050897///cobalt ion binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0030170///pyridoxal phosphate binding+++GO:0008732///L-allo-threonine aldolase activity+++GO:0004372///glycine hydroxymethyltransferase activity+++GO:0003682///chromatin binding+++GO:0070905///serine binding+++GO:0042802///identical protein binding+++GO:0003824///catalytic activity+++GO:0016597///amino acid binding","GO:0019264///glycine biosynthetic process from serine+++GO:0006545///glycine biosynthetic process+++GO:0051289///protein homotetramerization+++GO:0070536///protein K63-linked deubiquitination+++GO:0046653///tetrahydrofolate metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0006565///L-serine catabolic process+++GO:1903715///regulation of aerobic respiration+++GO:0032259///methylation+++GO:0070129///regulation of mitochondrial translation+++GO:0006564///L-serine biosynthetic process+++GO:0034340///response to type I interferon+++GO:0051262///protein tetramerization+++GO:0035999///tetrahydrofolate interconversion+++GO:0002082///regulation of oxidative phosphorylation+++GO:0046655///folic acid metabolic process+++GO:0006544///glycine metabolic process+++GO:1904482///cellular response to tetrahydrofolate+++GO:0006730///one-carbon metabolic process+++GO:0006563///L-serine metabolic process","serine hydroxymethyltransferase 2","[GLYM_HUMAN|Reviewed]RecName: Full=Serine hydroxymethyltransferase, mitochondrial; Short=SHMT; EC=2.1.2.1 {ECO:0000269|PubMed:24075985, ECO:0000269|PubMed:25619277, ECO:0000269|PubMed:29364879}; AltName: Full=Glycine hydroxymethyltransferase; AltName: Full=Serine methylase; Flags: Precursor;+++[A0A024RB99_HUMAN|Unreviewed]RecName: Full=Serine hydroxymethyltransferase {ECO:0000256|RuleBase:RU000585}; EC=2.1.2.1 {ECO:0000256|RuleBase:RU000585};+++[A0A0S2Z4J2_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase 2 isoform 2 {ECO:0000313|EMBL:ALQ33792.1};+++[B4DJQ3_HUMAN|Unreviewed]RecName: Full=Serine hydroxymethyltransferase {ECO:0000256|RuleBase:RU000585}; EC=2.1.2.1 {ECO:0000256|RuleBase:RU000585};+++[B4DLV4_HUMAN|Unreviewed]RecName: Full=Serine hydroxymethyltransferase {ECO:0000256|RuleBase:RU000585}; EC=2.1.2.1 {ECO:0000256|RuleBase:RU000585};+++[G3V241_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450452}; Flags: Fragment;+++[G3V2D2_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450594};+++[G3V2E4_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450610};+++[G3V2W0_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450893}; Flags: Fragment;+++[G3V2Y1_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450927};+++[G3V2Y4_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450930}; Flags: Fragment;+++[G3V3C6_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000451169};+++[G3V3Y8_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000451495}; Flags: Fragment;+++[G3V4T0_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000451968}; Flags: Fragment;+++[G3V4W5_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000452035}; Flags: Fragment;+++[G3V4X0_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000452045}; Flags: Fragment;+++[G3V540_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000452163};+++[G3V5L0_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000452404}; Flags: Fragment;+++[H0YIZ0_HUMAN|Unreviewed]SubName: Full=Serine hydroxymethyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450490}; Flags: Fragment;+++[Q5BJF5_HUMAN|Unreviewed]RecName: Full=Serine hydroxymethyltransferase {ECO:0000256|RuleBase:RU000585}; EC=2.1.2.1 {ECO:0000256|RuleBase:RU000585}; Flags: Fragment;+++[Q5HYG8_HUMAN|Unreviewed]RecName: Full=Serine hydroxymethyltransferase {ECO:0000256|RuleBase:RU000585}; EC=2.1.2.1 {ECO:0000256|RuleBase:RU000585};+++[Q9UMC7_HUMAN|Unreviewed]SubName: Full=SHMT protein {ECO:0000313|EMBL:CAB54844.1}; Flags: Fragment;+++[Q9UMC8_HUMAN|Unreviewed]SubName: Full=Cytosolic serine hydroxymethyltransferase {ECO:0000313|EMBL:CAB54843.1}; EC=2.1.2.1 {ECO:0000313|EMBL:CAB54843.1}; Flags: Fragment;+++[Q9UMC9_HUMAN|Unreviewed]SubName: Full=Cytosolic serine hydroxymethyltransferase {ECO:0000313|EMBL:CAB54842.1}; EC=2.1.2.1 {ECO:0000313|EMBL:CAB54842.1}; Flags: Fragment;+++[V9HW06_HUMAN|Unreviewed]RecName: Full=Serine hydroxymethyltransferase {ECO:0000256|RuleBase:RU000585}; EC=2.1.2.1 {ECO:0000256|RuleBase:RU000585};"]
[64754,"'SMYD3'",177.58,163.42,167.51,169.503333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane","GO:0000993///RNA polymerase II complex binding+++GO:0008168///methyltransferase activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0018024///histone-lysine N-methyltransferase activity","GO:0014904///myotube cell development+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032259///methylation+++GO:0006334///nucleosome assembly+++GO:0006469///negative regulation of protein kinase activity+++GO:0045184///establishment of protein localization+++GO:0071549///cellular response to dexamethasone stimulus","SET and MYND domain containing 3","[SMYD3_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SMYD3; EC=2.1.1.43; AltName: Full=SET and MYND domain-containing protein 3; AltName: Full=Zinc finger MYND domain-containing protein 1;+++[A8MXR1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SMYD3 {ECO:0000313|Ensembl:ENSP00000375712}; Flags: Fragment;+++[B0QZ88_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SMYD3 {ECO:0000313|Ensembl:ENSP00000385380};+++[B0QZ99_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SMYD3 {ECO:0000313|Ensembl:ENSP00000394281}; Flags: Fragment;+++[B0QZA0_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SMYD3 {ECO:0000313|Ensembl:ENSP00000408122}; Flags: Fragment;+++[B3KN46_HUMAN|Unreviewed]SubName: Full=SET and MYND domain containing 3, isoform CRA_a {ECO:0000313|EMBL:EAW77139.1}; SubName: Full=cDNA FLJ13532 fis, clone PLACE1006318, highly similar to SET and MYND domain-containing protein 3 {ECO:0000313|EMBL:BAG51208.1};+++[L0R6Q4_HUMAN|Unreviewed]SubName: Full=Alternative protein SMYD3 {ECO:0000313|EMBL:CCO13822.1};+++[Q3B7A0_HUMAN|Unreviewed]SubName: Full=SMYD3 protein {ECO:0000313|EMBL:AAI07726.1};"]
[64778,"'FNDC3B'",2920,2585,2677,2727.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003723///RNA binding+++GO:0005515///protein binding",null,"fibronectin type III domain containing 3B","[FND3B_HUMAN|Reviewed]RecName: Full=Fibronectin type III domain-containing protein 3B; AltName: Full=Factor for adipocyte differentiation 104; AltName: Full=HCV NS5A-binding protein 37;+++[C9JKH7_HUMAN|Unreviewed]SubName: Full=Fibronectin type III domain-containing protein 3B {ECO:0000313|Ensembl:ENSP00000389064}; Flags: Fragment;"]
[64789,"'EXO5'",54,58,56,56,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0004518///nuclease activity+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0004527///exonuclease activity+++GO:0003677///DNA binding+++GO:0051536///iron-sulfur cluster binding+++GO:0042803///protein homodimerization activity+++GO:0045145///single-stranded DNA 5'-3' exodeoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding","GO:0006259///DNA metabolic process+++GO:0036297///interstrand cross-link repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair","exonuclease 5","[EXO5_HUMAN|Reviewed]RecName: Full=Exonuclease V; Short=Exo V; Short=hExo5; EC=3.1.-.-; AltName: Full=Defects in morphology protein 1 homolog;+++[X6RCL8_HUMAN|Unreviewed]SubName: Full=Exonuclease V {ECO:0000313|Ensembl:ENSP00000391240}; Flags: Fragment;+++[X6RCY3_HUMAN|Unreviewed]SubName: Full=Exonuclease V {ECO:0000313|Ensembl:ENSP00000392115}; Flags: Fragment;+++[X6RF29_HUMAN|Unreviewed]SubName: Full=Exonuclease V {ECO:0000313|Ensembl:ENSP00000398437}; Flags: Fragment;+++[X6RK18_HUMAN|Unreviewed]SubName: Full=Exonuclease V {ECO:0000313|Ensembl:ENSP00000413565}; Flags: Fragment;+++[X6RLK1_HUMAN|Unreviewed]SubName: Full=Exonuclease V {ECO:0000313|Ensembl:ENSP00000416857}; Flags: Fragment;"]
[64843,"'ISL2'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0021524///visceral motor neuron differentiation+++GO:0048935///peripheral nervous system neuron development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0021520///spinal cord motor neuron cell fate specification+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045665///negative regulation of neuron differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0048666///neuron development+++GO:0048663///neuron fate commitment","ISL LIM homeobox 2","[ISL2_HUMAN|Reviewed]RecName: Full=Insulin gene enhancer protein ISL-2; Short=Islet-2;+++[F1T0J9_HUMAN|Unreviewed]SubName: Full=Insulin gene enhancer protein ISL-2 {ECO:0000313|EMBL:BAJ84073.1};+++[H0YN25_HUMAN|Unreviewed]SubName: Full=Insulin gene enhancer protein ISL-2 {ECO:0000313|Ensembl:ENSP00000453837};"]
[64856,"'VWA1'",197,207,164,189.333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005614///interstitial matrix+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome","GO:0042802///identical protein binding+++GO:0005201///extracellular matrix structural constituent","GO:0048266///behavioral response to pain+++GO:0030198///extracellular matrix organization+++GO:0044267///cellular protein metabolic process+++GO:0003429///growth plate cartilage chondrocyte morphogenesis+++GO:0043687///post-translational protein modification","von Willebrand factor A domain containing 1","[VWA1_HUMAN|Reviewed]RecName: Full=von Willebrand factor A domain-containing protein 1; Flags: Precursor;+++[A0A024R091_HUMAN|Unreviewed]SubName: Full=von Willebrand factor A domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW56201.1};+++[A0A024R0E4_HUMAN|Unreviewed]SubName: Full=von Willebrand factor A domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW56199.1};+++[J3QLP3_HUMAN|Unreviewed]SubName: Full=von Willebrand factor A domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000463643}; Flags: Fragment;+++[J3QRR0_HUMAN|Unreviewed]SubName: Full=von Willebrand factor A domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000464343}; Flags: Fragment;"]
[64900,"'LPIN3'",323,445,414,394,"00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways","H01290///Acute recurrent myoglobinuria+++H01117///Chronic recurrent multifocal osteomyelitis (CRMO)",null,"R02239///1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase   Phosphatidate + H2O <=> 1,2-Diacyl-sn-glycerol + Orthophosphate","GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus","GO:0016787///hydrolase activity+++GO:0003713///transcription coactivator activity+++GO:0008195///phosphatidate phosphatase activity","GO:0016311///dephosphorylation+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0019432///triglyceride biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0009062///fatty acid catabolic process+++GO:0032869///cellular response to insulin stimulus","lipin 3","[LPIN3_HUMAN|Reviewed]RecName: Full=Phosphatidate phosphatase LPIN3; EC=3.1.3.4; AltName: Full=Lipin-3; AltName: Full=Lipin-3-like;+++[H0Y5E1_HUMAN|Unreviewed]SubName: Full=Phosphatidate phosphatase LPIN3 {ECO:0000313|Ensembl:ENSP00000398092}; Flags: Fragment;"]
[64924,"'SLC30A5'",442,364.02,414,406.673333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0030141///secretory granule+++GO:0005794///Golgi apparatus+++GO:0030667///secretory granule membrane","GO:0008324///cation transmembrane transporter activity+++GO:0005385///zinc ion transmembrane transporter activity+++GO:0008270///zinc ion binding","GO:0055085///transmembrane transport+++GO:0006829///zinc ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0098655///cation transmembrane transport+++GO:0010043///response to zinc ion+++GO:0006811///ion transport+++GO:0010155///regulation of proton transport+++GO:0071577///zinc ion transmembrane transport+++GO:0006812///cation transport+++GO:0006824///cobalt ion transport","solute carrier family 30 member 5","[ZNT5_HUMAN|Reviewed]RecName: Full=Zinc transporter 5; Short=ZnT-5; AltName: Full=Solute carrier family 30 member 5; AltName: Full=ZnT-like transporter 1; Short=hZTL1;+++[D6REM2_HUMAN|Unreviewed]SubName: Full=Zinc transporter 5 {ECO:0000313|Ensembl:ENSP00000426751}; Flags: Fragment;+++[H0Y957_HUMAN|Unreviewed]SubName: Full=Zinc transporter 5 {ECO:0000313|Ensembl:ENSP00000423078}; Flags: Fragment;+++[H0YAH4_HUMAN|Unreviewed]SubName: Full=Zinc transporter 5 {ECO:0000313|Ensembl:ENSP00000427111}; Flags: Fragment;+++[Q9BY48_HUMAN|Unreviewed]SubName: Full=Putative disease resistance protein {ECO:0000313|EMBL:AAK14921.1}; SubName: Full=Zinc transporter 5 {ECO:0000313|Ensembl:ENSP00000483105};"]
[64983,"'MRPL32'",341,325,325,330.333333333333,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:1904813///ficolin-1-rich granule lumen+++GO:0070062///extracellular exosome+++GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0034774///secretory granule lumen+++GO:0000502///proteasome complex+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005654///nucleoplasm+++GO:0000932///P-body+++GO:0005739///mitochondrion+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0005839///proteasome core complex","GO:0003735///structural constituent of ribosome+++GO:0004298///threonine-type endopeptidase activity+++GO:0003723///RNA binding","GO:0009615///response to virus+++GO:0006412///translation+++GO:0070126///mitochondrial translational termination+++GO:0043687///post-translational protein modification+++GO:0043312///neutrophil degranulation+++GO:0016579///protein deubiquitination+++GO:0070125///mitochondrial translational elongation+++GO:0006511///ubiquitin-dependent protein catabolic process","mitochondrial ribosomal protein L32","[RM32_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L32, mitochondrial; Short=L32mt; Short=MRP-L32; AltName: Full=Mitochondrial large ribosomal subunit protein bL32m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[A4D1V4_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein L32 {ECO:0000313|EMBL:EAL24006.1}; SubName: Full=Mitochondrial ribosomal protein L32, isoform CRA_d {ECO:0000313|EMBL:EAW94157.1}; SubName: Full=cDNA, FLJ93927, Homo sapiens mitochondrial ribosomal protein L32 (MRPL32), nucleargene encoding mitochondrial protein, mRNA {ECO:0000313|EMBL:BAG36191.1};+++[B3KQX1_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein L32, isoform CRA_a {ECO:0000313|EMBL:EAW94154.1}; SubName: Full=cDNA FLJ33232 fis, clone ASTRO2002024, highly similar to 39S ribosomal protein L32, mitochondrial {ECO:0000313|EMBL:BAG52183.1};+++[H7BZU9_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L32, mitochondrial {ECO:0000313|Ensembl:ENSP00000391562}; Flags: Fragment;"]
[65010,"'SLC26A6'",171,201,177,183,"04978///Mineral absorption",{"$nulls":3},"GO:0012506///vesicle membrane+++GO:0016324///apical plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0034707///chloride channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031982///vesicle+++GO:0005887///integral component of plasma membrane+++GO:0031526///brush border membrane+++GO:0097225///sperm midpiece+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005783///endoplasmic reticulum","GO:0015499///formate transmembrane transporter activity+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015660///formate efflux transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0005515///protein binding+++GO:0015297///antiporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015562///efflux transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0005254///chloride channel activity+++GO:0030165///PDZ domain binding+++GO:0019531///oxalate transmembrane transporter activity+++GO:0008509///anion transmembrane transporter activity+++GO:0005452///inorganic anion exchanger activity","GO:0046724///oxalic acid secretion+++GO:0038166///angiotensin-activated signaling pathway+++GO:0048240///sperm capacitation+++GO:0006821///chloride transport+++GO:0008272///sulfate transport+++GO:1902358///sulfate transmembrane transport+++GO:0098656///anion transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0030321///transepithelial chloride transport+++GO:0015701///bicarbonate transport+++GO:0051453///regulation of intracellular pH+++GO:0071320///cellular response to cAMP+++GO:0050892///intestinal absorption+++GO:0015724///formate transport+++GO:0019532///oxalate transport+++GO:0051454///intracellular pH elevation+++GO:0015797///mannitol transport+++GO:0006820///anion transport+++GO:2001150///positive regulation of dipeptide transmembrane transport+++GO:0070633///transepithelial transport+++GO:0006811///ion transport+++GO:0071332///cellular response to fructose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0055085///transmembrane transport+++GO:0042045///epithelial fluid transport+++GO:0070528///protein kinase C signaling","solute carrier family 26 member 6","[S26A6_HUMAN|Reviewed]RecName: Full=Solute carrier family 26 member 6; AltName: Full=Anion exchange transporter; AltName: Full=Pendrin-like protein 1; Short=Pendrin-L1;+++[A0A0C4DFT5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000351597};+++[C9J6Y3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000405872}; Flags: Fragment;+++[C9JKR6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000401813}; Flags: Fragment;+++[F8W9I8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000307089};+++[G3XAC1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000337648}; SubName: Full=Solute carrier family 26, member 6, isoform CRA_i {ECO:0000313|EMBL:EAW64908.1};+++[H7BZ36_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000387532}; Flags: Fragment;+++[H7BZB1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000388721}; Flags: Fragment;+++[H7BZJ6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000389922}; Flags: Fragment;+++[H7C291_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26 member 6 {ECO:0000313|Ensembl:ENSP00000404607}; Flags: Fragment;+++[Q86YZ4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 26, member 6 {ECO:0000313|EMBL:BAC56861.1};+++[Q96MZ1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31675 fis, clone NT2RI2005087, highly similar to Homo sapiens putative anion transporter 1 mRNA {ECO:0000313|EMBL:BAB71126.1};+++[Q9Y3Y1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp586E1422 {ECO:0000313|EMBL:CAB43306.2}; Flags: Fragment;"]
[65095,"'KRI1'",452,533,479,488,"05231///Choline metabolism in cancer",{"$nulls":3},"GO:0005730///nucleolus+++GO:0030686///90S preribosome","GO:0003723///RNA binding","GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","KRI1 homolog","[KRI1_HUMAN|Reviewed]RecName: Full=Protein KRI1 homolog;+++[B7ZLF4_HUMAN|Unreviewed]SubName: Full=KRI1 protein {ECO:0000313|EMBL:AAI43771.1}; Flags: Fragment;+++[F8WFC1_HUMAN|Unreviewed]SubName: Full=Protein KRI1 homolog {ECO:0000313|Ensembl:ENSP00000412919}; Flags: Fragment;+++[H0YFD2_HUMAN|Unreviewed]SubName: Full=Protein KRI1 homolog {ECO:0000313|Ensembl:ENSP00000438000}; Flags: Fragment;+++[H0YG91_HUMAN|Unreviewed]SubName: Full=Protein KRI1 homolog {ECO:0000313|Ensembl:ENSP00000442213}; Flags: Fragment;+++[H0YH26_HUMAN|Unreviewed]SubName: Full=Protein KRI1 homolog {ECO:0000313|Ensembl:ENSP00000445789}; Flags: Fragment;"]
[6518,"'SLC2A5'",17,23,13,17.6666666666667,"04973///Carbohydrate digestion and absorption",{"$nulls":3},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0035579///specific granule membrane+++GO:0042383///sarcolemma+++GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0005353///fructose transmembrane transporter activity+++GO:0005215///transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0070061///fructose binding+++GO:0005355///glucose transmembrane transporter activity","GO:0005975///carbohydrate metabolic process+++GO:1904659///glucose transmembrane transport+++GO:0009750///response to fructose+++GO:0106001///intestinal hexose absorption+++GO:1990539///fructose import across plasma membrane+++GO:0008643///carbohydrate transport+++GO:0003044///regulation of systemic arterial blood pressure mediated by a chemical signal+++GO:0015755///fructose transmembrane transport+++GO:0055085///transmembrane transport+++GO:0043312///neutrophil degranulation+++GO:0071332///cellular response to fructose stimulus","solute carrier family 2 member 5","[GTR5_HUMAN|Reviewed]RecName: Full=Solute carrier family 2, facilitated glucose transporter member 5; AltName: Full=Fructose transporter; AltName: Full=Glucose transporter type 5, small intestine; Short=GLUT-5;+++[A0A140VJK5_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 81 {ECO:0000313|EMBL:AEE60992.1};+++[B4DG19_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51824, highly similar to Solute carrier family 2, facilitated glucose transporter member 5 {ECO:0000313|EMBL:BAG57630.1};+++[K7EIT1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 5 {ECO:0000313|Ensembl:ENSP00000464880}; Flags: Fragment;+++[K7EJR1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 5 {ECO:0000313|Ensembl:ENSP00000465285}; Flags: Fragment;+++[K7EJZ0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 5 {ECO:0000313|Ensembl:ENSP00000465382}; Flags: Fragment;+++[K7EQI3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 5 {ECO:0000313|Ensembl:ENSP00000467840}; Flags: Fragment;+++[L8E9T0_HUMAN|Unreviewed]SubName: Full=Alternative protein SLC2A5 {ECO:0000313|EMBL:CCQ43103.1};"]
[65243,"'ZFP69B'",122,109,93,108,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","ZFP69 zinc finger protein B","[ZF69B_HUMAN|Reviewed]RecName: Full=Zinc finger protein 69 homolog B; AltName: Full=Zinc finger protein 643;+++[D3DPV3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 643, isoform CRA_b {ECO:0000313|EMBL:EAX07218.1};+++[E9PS66_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 69 homolog B {ECO:0000313|Ensembl:ENSP00000435907};"]
[653082,"'ZDHHC11B'",125.23,221.99,177.49,174.903333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity","GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0006612///protein targeting to membrane","zinc finger DHHC-type containing 11B","[ZH11B_HUMAN|Reviewed]RecName: Full=Probable palmitoyltransferase ZDHHC11B; EC=2.3.1.225; AltName: Full=Zinc finger DHHC domain-containing protein 11B; Short=DHHC-11B;+++[A0A087X1A0_HUMAN|Unreviewed]SubName: Full=Probable palmitoyltransferase ZDHHC11B {ECO:0000313|Ensembl:ENSP00000484004};+++[F5H7P5_HUMAN|Unreviewed]RecName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119}; EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119};"]
[653316,"'FAM153C'",0,0,2.29,0.763333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0042788///polysomal ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0045202///synapse+++GO:0005925///focal adhesion+++GO:0005829///cytosol","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:1990932///5.8S rRNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0070180///large ribosomal subunit rRNA binding+++GO:0046872///metal ion binding","GO:0002181///cytoplasmic translation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006412///translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0097421///liver regeneration+++GO:0006413///translational initiation","family with sequence similarity 153 member C","[D6RA46_HUMAN|Unreviewed]SubName: Full=Protein FAM153C {ECO:0000313|Ensembl:ENSP00000423403}; Flags: Fragment;+++[D6RCA3_HUMAN|Unreviewed]SubName: Full=Protein FAM153C {ECO:0000313|Ensembl:ENSP00000422293}; Flags: Fragment;+++[D6RF56_HUMAN|Unreviewed]SubName: Full=Protein FAM153C {ECO:0000313|Ensembl:ENSP00000426621};"]
[653720,"'GOLGA8M'",45.28,59.96,70.31,58.5166666666667,"04530///Tight junction",{"$nulls":3},"GO:0000137///Golgi cis cisterna+++GO:0005801///cis-Golgi network+++GO:0005794///Golgi apparatus+++GO:0032580///Golgi cisterna membrane","GO:0008017///microtubule binding+++GO:0071933///Arp2/3 complex binding+++GO:0003779///actin binding+++GO:0017049///GTP-Rho binding","GO:0051225///spindle assembly+++GO:0007030///Golgi organization","golgin A8 family member M","[GOG8M_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 8M;"]
[654483,"'BOLA2B'",221.8,233.06,220.68,225.18,"04140///Autophagy - animal+++04145///Phagosome+++05152///Tuberculosis+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0044571///[2Fe-2S] cluster assembly","bolA family member 2B","[BOLA2_HUMAN|Reviewed]RecName: Full=BolA-like protein 2;+++[A0A087WZT3_HUMAN|Unreviewed]SubName: Full=BolA-like protein 2 {ECO:0000313|Ensembl:ENSP00000482868};+++[H3BPT9_HUMAN|Unreviewed]SubName: Full=BolA-like protein 2 {ECO:0000313|Ensembl:ENSP00000455468}; Flags: Fragment;+++[H3BV85_HUMAN|Unreviewed]SubName: Full=BolA-like protein 2 {ECO:0000313|Ensembl:ENSP00000457995}; Flags: Fragment;"]
[6560,"'SLC12A4'",2792.84,2634.64,2502.64,2643.37333333333,null,"H00606///Early infantile epileptic encephalopathy+++H00816///Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)+++H01815///Malignant migrating partial seizures in infancy",null,null,"GO:0005765///lysosomal membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0015377///cation:chloride symporter activity+++GO:0019901///protein kinase binding+++GO:0015293///symporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0005215///transporter activity","GO:0055075///potassium ion homeostasis+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:0071477///cellular hypotonic salinity response+++GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport+++GO:0055064///chloride ion homeostasis+++GO:0006813///potassium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0006884///cell volume homeostasis","solute carrier family 12 member 4","[S12A4_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 4; AltName: Full=Electroneutral potassium-chloride cotransporter 1; AltName: Full=Erythroid K-Cl cotransporter 1; Short=hKCC1;+++[B3KUS0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 4, isoform CRA_e {ECO:0000313|EMBL:EAW83195.1}; SubName: Full=cDNA FLJ40489 fis, clone TESTI2044194, highly similar to Solute carrier family 12 member 4 {ECO:0000313|EMBL:BAG53532.1};+++[B4DF30_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60065, highly similar to Solute carrier family 12 member 4 {ECO:0000313|EMBL:BAG57291.1};+++[I3L1N8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 4 {ECO:0000313|Ensembl:ENSP00000458975};+++[I3L4N6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 4 {ECO:0000313|Ensembl:ENSP00000461403};+++[J3QKM4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 4 {ECO:0000313|Ensembl:ENSP00000463148}; Flags: Fragment;+++[J3QRE2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 4 {ECO:0000313|Ensembl:ENSP00000464168}; Flags: Fragment;+++[J3QSF2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 4 {ECO:0000313|Ensembl:ENSP00000464660}; Flags: Fragment;"]
[6582,"'SLC22A2'",0,0,1,0.333333333333333,"05231///Choline metabolism in cancer",{"$nulls":3},"GO:0098793///presynapse+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane","GO:0022857///transmembrane transporter activity+++GO:0005326///neurotransmitter transporter activity+++GO:0015101///organic cation transmembrane transporter activity+++GO:0005215///transporter activity","GO:0015695///organic cation transport+++GO:0042136///neurotransmitter biosynthetic process+++GO:0007269///neurotransmitter secretion+++GO:0007589///body fluid secretion+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0055085///transmembrane transport+++GO:0006855///drug transmembrane transport","solute carrier family 22 member 2","[S22A2_HUMAN|Reviewed]RecName: Full=Solute carrier family 22 member 2; AltName: Full=Organic cation transporter 2; Short=hOCT2;+++[Q5T7Q5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 2 {ECO:0000313|Ensembl:ENSP00000355919};"]
[65979,"'PHACTR4'",1187.63,1199.83,1105.04,1164.16666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0005737///cytoplasm+++GO:0042995///cell projection","GO:0003779///actin binding+++GO:0019888///protein phosphatase regulator activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0072542///protein phosphatase activator activity+++GO:0008157///protein phosphatase 1 binding","GO:0007266///Rho protein signal transduction+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0061386///closure of optic fissure+++GO:0043085///positive regulation of catalytic activity+++GO:0001843///neural tube closure+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:2001045///negative regulation of integrin-mediated signaling pathway+++GO:0001755///neural crest cell migration+++GO:0048484///enteric nervous system development+++GO:0007399///nervous system development+++GO:0051726///regulation of cell cycle+++GO:0030036///actin cytoskeleton organization+++GO:0007275///multicellular organism development","phosphatase and actin regulator 4","[PHAR4_HUMAN|Reviewed]RecName: Full=Phosphatase and actin regulator 4;+++[A0A0J9YVR0_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[A0A0J9YWV8_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[A0A0J9YY52_HUMAN|Unreviewed]SubName: Full=Phosphatase and actin regulator 4 {ECO:0000313|Ensembl:ENSP00000488693};"]
[65998,"'C11orf95'",480,499,480,486.333333333333,{"$nulls":5},"GO:0003676///nucleic acid binding","GO:0045892///negative regulation of transcription, DNA-templated","chromosome 11 open reading frame 95","[CK095_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf95;+++[A0A087WU89_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf95 {ECO:0000313|Ensembl:ENSP00000478462}; Flags: Fragment;+++[A0A087WZS6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf95 {ECO:0000313|Ensembl:ENSP00000482857};+++[A0A087X051_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf95 {ECO:0000313|Ensembl:ENSP00000483097}; Flags: Fragment;"]
[6608,"'SMO'",1237,1261,1151,1216.33333333333,"04360///Axon guidance+++05217///Basal cell carcinoma+++05205///Proteoglycans in cancer+++04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway+++05200///Pathways in cancer","H01556///Meningioma+++H00039///Basal cell carcinoma+++H01667///Medulloblastoma","M00678///Hedgehog signaling",null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0097542///ciliary tip+++GO:0005634///nucleus+++GO:0060170///ciliary membrane+++GO:0030666///endocytic vesicle membrane+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0005113///patched binding+++GO:0008144///drug binding+++GO:0017147///Wnt-protein binding+++GO:0004930///G protein-coupled receptor activity","GO:0021910///smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0021938///smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation+++GO:0048741///skeletal muscle fiber development+++GO:0003323///type B pancreatic cell development+++GO:0021794///thalamus development+++GO:0061053///somite development+++GO:0021904///dorsal/ventral neural tube patterning+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0070986///left/right axis specification+++GO:0010629///negative regulation of gene expression+++GO:0050821///protein stabilization+++GO:0001947///heart looping+++GO:0060248///detection of cell density by contact stimulus involved in contact inhibition+++GO:2000036///regulation of stem cell population maintenance+++GO:0042307///positive regulation of protein import into nucleus+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0060413///atrial septum morphogenesis+++GO:0007228///positive regulation of hh target transcription factor activity+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0046622///positive regulation of organ growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0003140///determination of left/right asymmetry in lateral mesoderm+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0021987///cerebral cortex development+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0043392///negative regulation of DNA binding+++GO:0048853///forebrain morphogenesis+++GO:0021542///dentate gyrus development+++GO:0021696///cerebellar cortex morphogenesis+++GO:2000826///regulation of heart morphogenesis+++GO:0016055///Wnt signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0001649///osteoblast differentiation+++GO:0072285///mesenchymal to epithelial transition involved in metanephric renal vesicle formation+++GO:0061113///pancreas morphogenesis+++GO:0021953///central nervous system neuron differentiation+++GO:0051799///negative regulation of hair follicle development+++GO:0001570///vasculogenesis+++GO:0010628///positive regulation of gene expression+++GO:0007224///smoothened signaling pathway+++GO:0001701///in utero embryonic development+++GO:0043066///negative regulation of apoptotic process+++GO:0034504///protein localization to nucleus+++GO:0007494///midgut development+++GO:0048143///astrocyte activation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035264///multicellular organism growth+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0060684///epithelial-mesenchymal cell signaling+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0031069///hair follicle morphogenesis+++GO:0051451///myoblast migration+++GO:0007371///ventral midline determination+++GO:0001708///cell fate specification+++GO:0009952///anterior/posterior pattern specification+++GO:0072001///renal system development+++GO:0071397///cellular response to cholesterol+++GO:0010468///regulation of gene expression+++GO:0001755///neural crest cell migration","smoothened, frizzled class receptor","[SMO_HUMAN|Reviewed]RecName: Full=Smoothened homolog; Short=SMO; AltName: Full=Protein Gx; Flags: Precursor;"]
[6622,"'SNCA'",665,716,639,673.333333333333,"05010///Alzheimer's disease+++05012///Parkinson's disease","H01600///Parkinsonian syndrome+++H00066///Lewy body dementia (LBD)+++H00057///Parkinson's disease (PD)",null,null,"GO:0030672///synaptic vesicle membrane+++GO:0005576///extracellular region+++GO:0031092///platelet alpha granule membrane+++GO:0099512///supramolecular fiber+++GO:0016234///inclusion body+++GO:0005794///Golgi apparatus+++GO:0005938///cell cortex+++GO:0043679///axon terminus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030426///growth cone+++GO:0005741///mitochondrial outer membrane+++GO:0005764///lysosome+++GO:0030424///axon+++GO:0005743///mitochondrial inner membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0005759///mitochondrial matrix+++GO:0005615///extracellular space+++GO:0030054///cell junction+++GO:0008021///synaptic vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005640///nuclear outer membrane+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005840///ribosome+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0016020///membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0098794///postsynapse","GO:0000287///magnesium ion binding+++GO:0005504///fatty acid binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0046872///metal ion binding+++GO:0048156///tau protein binding+++GO:0060961///phospholipase D inhibitor activity+++GO:0042393///histone binding+++GO:0051219///phosphoprotein binding+++GO:0005543///phospholipid binding+++GO:0019894///kinesin binding+++GO:0003779///actin binding+++GO:0047485///protein N-terminus binding+++GO:0008270///zinc ion binding+++GO:0005509///calcium ion binding+++GO:0008017///microtubule binding+++GO:0005507///copper ion binding+++GO:0019904///protein domain specific binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0043274///phospholipase binding+++GO:0016491///oxidoreductase activity+++GO:0043014///alpha-tubulin binding+++GO:0070840///dynein complex binding+++GO:0048487///beta-tubulin binding+++GO:0019899///enzyme binding+++GO:1903136///cuprous ion binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0030544///Hsp70 protein binding","GO:1903421///regulation of synaptic vesicle recycling+++GO:0048489///synaptic vesicle transport+++GO:0040012///regulation of locomotion+++GO:0060079///excitatory postsynaptic potential+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0032496///response to lipopolysaccharide+++GO:0042220///response to cocaine+++GO:0031648///protein destabilization+++GO:1904715///negative regulation of chaperone-mediated autophagy+++GO:1902957///negative regulation of mitochondrial electron transport, NADH to ubiquinone+++GO:0051585///negative regulation of dopamine uptake involved in synaptic transmission+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0010517///regulation of phospholipase activity+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0008344///adult locomotory behavior+++GO:0071872///cellular response to epinephrine stimulus+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0035067///negative regulation of histone acetylation+++GO:0055074///calcium ion homeostasis+++GO:0050806///positive regulation of synaptic transmission+++GO:0071280///cellular response to copper ion+++GO:1901215///negative regulation of neuron death+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0070495///negative regulation of thrombin-activated receptor signaling pathway+++GO:0001933///negative regulation of protein phosphorylation+++GO:0070555///response to interleukin-1+++GO:0051621///regulation of norepinephrine uptake+++GO:0043030///regulation of macrophage activation+++GO:0034341///response to interferon-gamma+++GO:0006644///phospholipid metabolic process+++GO:0032410///negative regulation of transporter activity+++GO:0043066///negative regulation of apoptotic process+++GO:0001774///microglial cell activation+++GO:0043065///positive regulation of apoptotic process+++GO:0031623///receptor internalization+++GO:0046928///regulation of neurotransmitter secretion+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0007006///mitochondrial membrane organization+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0051583///dopamine uptake involved in synaptic transmission+++GO:0032026///response to magnesium ion+++GO:0032769///negative regulation of monooxygenase activity+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:0045920///negative regulation of exocytosis+++GO:0060291///long-term synaptic potentiation+++GO:0045807///positive regulation of endocytosis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010040///response to iron(II) ion+++GO:0022898///regulation of transmembrane transporter activity+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0006638///neutral lipid metabolic process+++GO:0042493///response to drug+++GO:0048148///behavioral response to cocaine+++GO:0050808///synapse organization+++GO:0042416///dopamine biosynthetic process+++GO:0097435///supramolecular fiber organization+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050812///regulation of acyl-CoA biosynthetic process+++GO:0014059///regulation of dopamine secretion+++GO:1901214///regulation of neuron death+++GO:1903285///positive regulation of hydrogen peroxide catabolic process+++GO:0051622///negative regulation of norepinephrine uptake+++GO:1903284///positive regulation of glutathione peroxidase activity+++GO:0044267///cellular protein metabolic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007568///aging+++GO:0007268///chemical synaptic transmission+++GO:0014048///regulation of glutamate secretion+++GO:0006915///apoptotic process+++GO:0001963///synaptic transmission, dopaminergic+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045963///negative regulation of dopamine metabolic process+++GO:0050729///positive regulation of inflammatory response+++GO:0048488///synaptic vesicle endocytosis+++GO:0031115///negative regulation of microtubule polymerization+++GO:1905606///regulation of presynapse assembly+++GO:0034599///cellular response to oxidative stress+++GO:0006631///fatty acid metabolic process+++GO:0001921///positive regulation of receptor recycling+++GO:1901216///positive regulation of neuron death+++GO:1904307///response to desipramine+++GO:0042417///dopamine metabolic process+++GO:0051612///negative regulation of serotonin uptake+++GO:0060732///positive regulation of inositol phosphate biosynthetic process+++GO:0061024///membrane organization","synuclein alpha","[SYUA_HUMAN|Reviewed]RecName: Full=Alpha-synuclein; AltName: Full=Non-A beta component of AD amyloid; AltName: Full=Non-A4 component of amyloid precursor; Short=NACP;+++[D6RA31_HUMAN|Unreviewed]SubName: Full=Alpha-synuclein {ECO:0000313|Ensembl:ENSP00000423445}; Flags: Fragment;+++[E7EPV7_HUMAN|Unreviewed]RecName: Full=Alpha-synuclein {ECO:0000256|RuleBase:RU361225};+++[F6L6N6_HUMAN|Unreviewed]SubName: Full=Synuclein alpha-140 {ECO:0000313|EMBL:AEG20817.1}; Flags: Fragment;+++[H6UYS0_HUMAN|Unreviewed]RecName: Full=Alpha-synuclein {ECO:0000256|RuleBase:RU361225};+++[H6UYS5_HUMAN|Unreviewed]RecName: Full=Alpha-synuclein {ECO:0000256|RuleBase:RU361225};+++[H6UYS7_HUMAN|Unreviewed]RecName: Full=Alpha-synuclein {ECO:0000256|RuleBase:RU361225};+++[Q4W5L2_HUMAN|Unreviewed]RecName: Full=Alpha-synuclein {ECO:0000256|RuleBase:RU361225}; Flags: Fragment;"]
[6637,"'SNRPG'",217,156,210,194.333333333333,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00352///Spliceosome, U2-snRNP+++M00398///Sm core complex+++M00351///Spliceosome, U1-snRNP",null,"GO:0071013///catalytic step 2 spliceosome+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0005686///U2 snRNP+++GO:0005682///U5 snRNP+++GO:0005687///U4 snRNP+++GO:0043186///P granule+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0034709///methylosome+++GO:0005689///U12-type spliceosomal complex+++GO:0071004///U2-type prespliceosome+++GO:0005683///U7 snRNP+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0071005///U2-type precatalytic spliceosome+++GO:0005685///U1 snRNP+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex+++GO:0034719///SMN-Sm protein complex","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0008334///histone mRNA metabolic process+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000387///spliceosomal snRNP assembly+++GO:0006369///termination of RNA polymerase II transcription+++GO:0051170///import into nucleus+++GO:0000245///spliceosomal complex assembly","small nuclear ribonucleoprotein polypeptide G","[RUXG_HUMAN|Reviewed]RecName: Full=Small nuclear ribonucleoprotein G; Short=snRNP-G; AltName: Full=Sm protein G; Short=Sm-G; Short=SmG;+++[C9JVQ0_HUMAN|Unreviewed]RecName: Full=Small nuclear ribonucleoprotein G {ECO:0000256|RuleBase:RU365052}; Short=snRNP-G {ECO:0000256|RuleBase:RU365052};+++[F5H013_HUMAN|Unreviewed]RecName: Full=Small nuclear ribonucleoprotein G {ECO:0000256|RuleBase:RU365052}; Short=snRNP-G {ECO:0000256|RuleBase:RU365052};+++[Q49AN9_HUMAN|Unreviewed]RecName: Full=Small nuclear ribonucleoprotein G {ECO:0000256|RuleBase:RU365052}; Short=snRNP-G {ECO:0000256|RuleBase:RU365052};"]
[664,"'BNIP3'",1376,1177,1192,1248.33333333333,"05134///Legionellosis+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0005737///cytoplasm+++GO:0005635///nuclear envelope+++GO:0005739///mitochondrion+++GO:0014069///postsynaptic density+++GO:0016021///integral component of membrane+++GO:0005740///mitochondrial envelope+++GO:0030425///dendrite+++GO:0005634///nucleus+++GO:0005741///mitochondrial outer membrane+++GO:0031966///mitochondrial membrane+++GO:0005654///nucleoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0051020///GTPase binding+++GO:0042803///protein homodimerization activity","GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0008626///granzyme-mediated apoptotic signaling pathway+++GO:1990144///intrinsic apoptotic signaling pathway in response to hypoxia+++GO:0035694///mitochondrial protein catabolic process+++GO:0048102///autophagic cell death+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0071279///cellular response to cobalt ion+++GO:0072593///reactive oxygen species metabolic process+++GO:0071456///cellular response to hypoxia+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:0010821///regulation of mitochondrion organization+++GO:0010940///positive regulation of necrotic cell death+++GO:0051607///defense response to virus+++GO:0043066///negative regulation of apoptotic process+++GO:0010508///positive regulation of autophagy+++GO:0009617///response to bacterium+++GO:0071260///cellular response to mechanical stimulus+++GO:0006915///apoptotic process+++GO:0048709///oligodendrocyte differentiation+++GO:0043243///positive regulation of protein complex disassembly+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0060548///negative regulation of cell death+++GO:0043065///positive regulation of apoptotic process+++GO:0001666///response to hypoxia+++GO:0021987///cerebral cortex development+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:0043068///positive regulation of programmed cell death+++GO:0008219///cell death+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0045837///negative regulation of membrane potential+++GO:0055093///response to hyperoxia+++GO:0070301///cellular response to hydrogen peroxide+++GO:0016239///positive regulation of macroautophagy+++GO:1901998///toxin transport+++GO:0016032///viral process+++GO:0090141///positive regulation of mitochondrial fission+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0000422///autophagy of mitochondrion+++GO:0050873///brown fat cell differentiation+++GO:1903715///regulation of aerobic respiration+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:0051402///neuron apoptotic process+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0097193///intrinsic apoptotic signaling pathway","BCL2 interacting protein 3","[BNIP3_HUMAN|Reviewed]RecName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 3;+++[A0A0J9YW18_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000487769}; Flags: Fragment;+++[A0A2U8ZU93_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B interacting protein 3 {ECO:0000313|EMBL:AWO14533.1};+++[F6RP06_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000446145}; Flags: Fragment;+++[Q66K24_HUMAN|Unreviewed]SubName: Full=BNIP3 protein {ECO:0000313|EMBL:AAH80643.1}; Flags: Fragment;+++[Q6NVY4_HUMAN|Unreviewed]SubName: Full=BNIP3 protein {ECO:0000313|EMBL:AAH67818.1}; Flags: Fragment;"]
[6654,"'SOS1'",690,689,694,691,"04650///Natural killer cell mediated cytotoxicity+++04150///mTOR signaling pathway+++05231///Choline metabolism in cancer+++04320///Dorso-ventral axis formation+++04012///ErbB signaling pathway+++04915///Estrogen signaling pathway+++04810///Regulation of actin cytoskeleton+++01522///Endocrine resistance+++05200///Pathways in cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++04714///Thermogenesis+++05221///Acute myeloid leukemia+++04662///B cell receptor signaling pathway+++05206///MicroRNAs in cancer+++05034///Alcoholism+++04664///Fc epsilon RI signaling pathway+++04062///Chemokine signaling pathway+++04660///T cell receptor signaling pathway+++04540///Gap junction+++04722///Neurotrophin signaling pathway+++04912///GnRH signaling pathway+++05163///Human cytomegalovirus infection+++04068///FoxO signaling pathway+++05160///Hepatitis C+++04151///PI3K-Akt signaling pathway+++04510///Focal adhesion+++05211///Renal cell carcinoma+++05225///Hepatocellular carcinoma+++04630///Jak-STAT signaling pathway+++05215///Prostate cancer+++05223///Non-small cell lung cancer+++05224///Breast cancer+++05214///Glioma+++05226///Gastric cancer+++04910///Insulin signaling pathway+++04014///Ras signaling pathway+++04926///Relaxin signaling pathway+++05220///Chronic myeloid leukemia+++04010///MAPK signaling pathway+++05165///Human papillomavirus infection+++04013///MAPK signaling pathway - fly+++04917///Prolactin signaling pathway+++05213///Endometrial cancer+++05205///Proteoglycans in cancer+++05210///Colorectal cancer+++04072///Phospholipase D signaling pathway","H01738///Noonan syndrome+++H00523///Noonan syndrome and related disorders+++H01250///Hereditary gingival fibromatosis (HGF)",null,null,"GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0000786///nucleosome+++GO:0014069///postsynaptic density+++GO:0031093///platelet alpha granule lumen+++GO:0043025///neuronal cell body","GO:0008083///growth factor activity+++GO:0004252///serine-type endopeptidase activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0004713///protein tyrosine kinase activity+++GO:0017124///SH3 domain binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0042802///identical protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0042056///chemoattractant activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:2000573///positive regulation of DNA biosynthetic process+++GO:0061384///heart trabecula morphogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:0030212///hyaluronan metabolic process+++GO:0042129///regulation of T cell proliferation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0070572///positive regulation of neuron projection regeneration+++GO:0001782///B cell homeostasis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050900///leukocyte migration+++GO:0051450///myoblast proliferation+++GO:0032733///positive regulation of interleukin-10 production+++GO:0031643///positive regulation of myelination+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0048514///blood vessel morphogenesis+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0050918///positive chemotaxis+++GO:0010469///regulation of signaling receptor activity+++GO:0008283///cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0007411///axon guidance+++GO:1901299///negative regulation of hydrogen peroxide-mediated programmed cell death+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007265///Ras protein signal transduction+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007296///vitellogenesis+++GO:0001942///hair follicle development+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0050728///negative regulation of inflammatory response+++GO:0006508///proteolysis+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0010507///negative regulation of autophagy+++GO:0035264///multicellular organism growth+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0003007///heart morphogenesis+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0060326///cell chemotaxis+++GO:0045766///positive regulation of angiogenesis+++GO:0001889///liver development+++GO:0060665///regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling+++GO:1904693///midbrain morphogenesis+++GO:0043547///positive regulation of GTPase activity+++GO:0000165///MAPK cascade+++GO:0002576///platelet degranulation+++GO:0003209///cardiac atrium morphogenesis+++GO:0000902///cell morphogenesis+++GO:0060021///roof of mouth development+++GO:0030335///positive regulation of cell migration+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0061029///eyelid development in camera-type eye+++GO:0000187///activation of MAPK activity+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0000278///mitotic cell cycle+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:1900744///regulation of p38MAPK cascade+++GO:0043065///positive regulation of apoptotic process+++GO:1902947///regulation of tau-protein kinase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0038128///ERBB2 signaling pathway+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0007165///signal transduction+++GO:0031100///animal organ regeneration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0002260///lymphocyte homeostasis+++GO:0003344///pericardium morphogenesis+++GO:0032715///negative regulation of interleukin-6 production+++GO:2000973///regulation of pro-B cell differentiation+++GO:0035023///regulation of Rho protein signal transduction","SOS Ras/Rac guanine nucleotide exchange factor 1","[SOS1_HUMAN|Reviewed]RecName: Full=Son of sevenless homolog 1; Short=SOS-1;+++[A0A2R8YEI1_HUMAN|Unreviewed]SubName: Full=Hepatocyte growth factor {ECO:0000313|Ensembl:ENSP00000494355};+++[A0A2X0SG47_HUMAN|Unreviewed]SubName: Full=SOS1 {ECO:0000313|EMBL:SPT35795.1}; Flags: Fragment;+++[C9JDP4_HUMAN|Unreviewed]SubName: Full=Hepatocyte growth factor {ECO:0000313|Ensembl:ENSP00000396307}; Flags: Fragment;+++[C9JS80_HUMAN|Unreviewed]SubName: Full=Hepatocyte growth factor {ECO:0000313|Ensembl:ENSP00000388592}; Flags: Fragment;+++[C9K0N6_HUMAN|Unreviewed]SubName: Full=Son of sevenless homolog 1 {ECO:0000313|Ensembl:ENSP00000393899}; Flags: Fragment;+++[C9WSJ3_HUMAN|Unreviewed]SubName: Full=Hepatocyte growth factor isoform 6 {ECO:0000313|EMBL:ACX45437.1};+++[C9WSJ4_HUMAN|Unreviewed]SubName: Full=Hepatocyte growth factor isoform 6 {ECO:0000313|EMBL:ACX45438.1};+++[G5E9C8_HUMAN|Unreviewed]SubName: Full=Son of sevenless homolog 1 (Drosophila), isoform CRA_d {ECO:0000313|EMBL:EAX00353.1};+++[Q53SF8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SOS1 {ECO:0000313|EMBL:AAX93186.1}; Flags: Fragment;+++[Q8NIA3_HUMAN|Unreviewed]SubName: Full=Alternate SOS1 {ECO:0000313|EMBL:AAM22406.1};+++[Q9UKX9_HUMAN|Unreviewed]SubName: Full=SOS1 {ECO:0000313|EMBL:AAF04460.1}; Flags: Fragment;"]
[6671,"'SP4'",121.04,192,126.78,146.606666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding","GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006357///regulation of transcription by RNA polymerase II","Sp4 transcription factor","[SP4_HUMAN|Reviewed]RecName: Full=Transcription factor Sp4; AltName: Full=SPR-1;+++[C9JUS7_HUMAN|Unreviewed]SubName: Full=Transcription factor Sp4 {ECO:0000313|Ensembl:ENSP00000393623}; Flags: Fragment;+++[F8WB93_HUMAN|Unreviewed]SubName: Full=Transcription factor Sp4 {ECO:0000313|Ensembl:ENSP00000390817};+++[L0R552_HUMAN|Unreviewed]SubName: Full=Alternative protein SP4 {ECO:0000313|EMBL:CCO13823.1};+++[Q32M51_HUMAN|Unreviewed]SubName: Full=SP4 protein {ECO:0000313|EMBL:AAI09302.1};"]
[6697,"'SPR'",226,260,217,234.333333333333,"01100///Metabolic pathways+++00790///Folate biosynthesis","H00831///Primary dystonia","M00842///Tetrahydrobiopterin biosynthesis, GTP => BH4","R11763///6-(1'-hydroxy-2'-oxopropyl)-tetrahydropterin:NADP+ oxidoreductase   6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H++++R08208///tetrahydrobiopterin:NADP+ oxidoreductase (6-pyruvoyltetrahydropterin-forming)   Tetrahydrobiopterin + 2 NADP+ <=> 6-Pyruvoyltetrahydropterin + 2 NADPH + 2 H++++R11762///6-Lactoyl-5,6,7,8-tetrahydropterin <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin+++R01813///tetrahydrobiopterin:NADP+ oxidoreductase   Tetrahydrobiopterin + NADP+ <=> 6-Lactoyl-5,6,7,8-tetrahydropterin + NADPH + H++++R02975///7,8-Dihydrobiopterin:NADP+ oxidoreductase   7,8-Dihydrobiopterin + NADP+ <=> Sepiapterin + NADPH + H+","GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome","GO:0050661///NADP binding+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0004757///sepiapterin reductase activity","GO:0050999///regulation of nitric-oxide synthase activity+++GO:0006809///nitric oxide biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0051186///cofactor metabolic process+++GO:0006729///tetrahydrobiopterin biosynthetic process","sepiapterin reductase","[SPRE_HUMAN|Reviewed]RecName: Full=Sepiapterin reductase; Short=SPR; EC=1.1.1.153;"]
[6720,"'SREBF1'",4001,5497,4815,4771,"04931///Insulin resistance+++04910///Insulin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04152///AMPK signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0031410///cytoplasmic vesicle+++GO:0005635///nuclear envelope+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0032810///sterol response element binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044877///protein-containing complex binding+++GO:0043565///sequence-specific DNA binding+++GO:0019901///protein kinase binding+++GO:0004879///nuclear receptor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008047///enzyme activator activity+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0033993///response to lipid+++GO:0003062///regulation of heart rate by chemical signal+++GO:0006355///regulation of transcription, DNA-templated+++GO:0019217///regulation of fatty acid metabolic process+++GO:0032526///response to retinoic acid+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007568///aging+++GO:0046676///negative regulation of insulin secretion+++GO:0009749///response to glucose+++GO:0043434///response to peptide hormone+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0042493///response to drug+++GO:0007623///circadian rhythm+++GO:0008202///steroid metabolic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0008286///insulin receptor signaling pathway+++GO:0031647///regulation of protein stability+++GO:0032869///cellular response to insulin stimulus+++GO:0014070///response to organic cyclic compound+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:0043085///positive regulation of catalytic activity+++GO:0008203///cholesterol metabolic process+++GO:0030522///intracellular receptor signaling pathway+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0071398///cellular response to fatty acid+++GO:0008610///lipid biosynthetic process+++GO:0032570///response to progesterone+++GO:0006629///lipid metabolic process+++GO:0045444///fat cell differentiation+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0032094///response to food+++GO:0031065///positive regulation of histone deacetylation+++GO:0030324///lung development+++GO:0009267///cellular response to starvation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0033762///response to glucagon+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051591///response to cAMP+++GO:0070542///response to fatty acid+++GO:0050796///regulation of insulin secretion","sterol regulatory element binding transcription factor 1","[SRBP1_HUMAN|Reviewed]RecName: Full=Sterol regulatory element-binding protein 1; Short=SREBP-1; AltName: Full=Class D basic helix-loop-helix protein 1; Short=bHLHd1; AltName: Full=Sterol regulatory element-binding transcription factor 1; Contains: RecName: Full=Processed sterol regulatory element-binding protein 1;+++[A8MTU8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38006 fis, clone CTONG2012422, highly similar to Sterol regulatory element-binding protein 1 {ECO:0000313|EMBL:BAG53027.1};+++[B3KR77_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33812 fis, clone CTONG2002270, highly similar to Sterol regulatory element-binding protein 1 {ECO:0000313|EMBL:BAG52289.1};+++[B5MD58_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000379106};+++[F6V242_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000411516}; Flags: Fragment;+++[J3QLB6_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000463474}; Flags: Fragment;+++[K7EIW8_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000464923}; Flags: Fragment;+++[K7EKR7_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000465747}; Flags: Fragment;+++[K7EMD1_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000466453}; Flags: Fragment;+++[K7EMT8_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000466643}; Flags: Fragment;+++[S4R3B4_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000474121}; Flags: Fragment;+++[X6RBE4_HUMAN|Unreviewed]SubName: Full=Sterol regulatory element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000379100};"]
[6744,"'ITPRID2'",4775,5370,4965,5036.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005102///signaling receptor binding+++GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","ITPR interacting domain containing 2","[ITPI2_HUMAN|Reviewed]RecName: Full=Protein ITPRID2 {ECO:0000305}; AltName: Full=Cleavage signal-1 protein {ECO:0000303|PubMed:1555770}; Short=CS-1 {ECO:0000303|PubMed:1555770}; AltName: Full=ITPR-interacting domain-containing protein 2 {ECO:0000305}; AltName: Full=Ki-ras-induced actin-interacting protein {ECO:0000303|PubMed:14673706}; AltName: Full=Sperm-specific antigen 2;+++[E7EUL7_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000386916};+++[E9PHV5_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000387319};+++[F2Z295_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000392049};+++[H7BZ26_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000387420}; Flags: Fragment;"]
[6755,"'SSTR5'",0,0,2,0.666666666666667,"04080///Neuroactive ligand-receptor interaction+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004994///somatostatin receptor activity+++GO:0042923///neuropeptide binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0050796///regulation of insulin secretion+++GO:0038170///somatostatin signaling pathway+++GO:0032467///positive regulation of cytokinesis+++GO:0008285///negative regulation of cell proliferation+++GO:0007218///neuropeptide signaling pathway+++GO:0042593///glucose homeostasis+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0071385///cellular response to glucocorticoid stimulus","somatostatin receptor 5","[SSR5_HUMAN|Reviewed]RecName: Full=Somatostatin receptor type 5; Short=SS-5-R; Short=SS5-R; Short=SS5R;+++[D2CFK4_HUMAN|Unreviewed]SubName: Full=Somatostatin receptor subtype 5B {ECO:0000313|EMBL:ABE27002.1};+++[D2CFK5_HUMAN|Unreviewed]SubName: Full=Somatostatin receptor subtype 5C {ECO:0000313|EMBL:ABE27003.1};"]
[6777,"'STAT5B'",351.02,372.33,269.25,330.866666666667,"04917///Prolactin signaling pathway+++05220///Chronic myeloid leukemia+++04659///Th17 cell differentiation+++05166///HTLV-I infection+++05221///Acute myeloid leukemia+++05203///Viral carcinogenesis+++04658///Th1 and Th2 cell differentiation+++05200///Pathways in cancer+++05162///Measles+++04012///ErbB signaling pathway+++04062///Chemokine signaling pathway+++05223///Non-small cell lung cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++04217///Necroptosis+++05161///Hepatitis B+++04630///Jak-STAT signaling pathway","H00931///Growth hormone insensitivity with immunodeficiency","M00684///JAK-STAT signaling",null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0035259///glucocorticoid receptor binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046983///protein dimerization activity","GO:0032819///positive regulation of natural killer cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019530///taurine metabolic process+++GO:0032870///cellular response to hormone stimulus+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0030155///regulation of cell adhesion+++GO:0038113///interleukin-9-mediated signaling pathway+++GO:0007165///signal transduction+++GO:0046543///development of secondary female sexual characteristics+++GO:0030856///regulation of epithelial cell differentiation+++GO:0019218///regulation of steroid metabolic process+++GO:0007259///JAK-STAT cascade+++GO:0050729///positive regulation of inflammatory response+++GO:0042448///progesterone metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043066///negative regulation of apoptotic process+++GO:0045579///positive regulation of B cell differentiation+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0019915///lipid storage+++GO:0038110///interleukin-2-mediated signaling pathway+++GO:0045588///positive regulation of gamma-delta T cell differentiation+++GO:0045086///positive regulation of interleukin-2 biosynthetic process+++GO:0001779///natural killer cell differentiation+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0040018///positive regulation of multicellular organism growth+++GO:0040014///regulation of multicellular organism growth+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0046544///development of secondary male sexual characteristics+++GO:0001553///luteinization+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0071363///cellular response to growth factor stimulus+++GO:0007565///female pregnancy+++GO:0007595///lactation+++GO:0048541///Peyer's patch development+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0007548///sex differentiation+++GO:0032355///response to estradiol+++GO:0070669///response to interleukin-2+++GO:0070672///response to interleukin-15+++GO:0070670///response to interleukin-4+++GO:0033077///T cell differentiation in thymus+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0097531///mast cell migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0043029///T cell homeostasis","signal transducer and activator of transcription 5B","[STA5B_HUMAN|Reviewed]RecName: Full=Signal transducer and activator of transcription 5B;+++[C9J4I3_HUMAN|Unreviewed]SubName: Full=Signal transducer and activator of transcription 5B {ECO:0000313|Ensembl:ENSP00000398379}; Flags: Fragment;"]
[6810,"'STX4'",526,544,480,516.666666666667,"04130///SNARE interactions in vesicular transport+++04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0098794///postsynapse+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0042581///specific granule+++GO:0012505///endomembrane system+++GO:0005622///intracellular+++GO:0005773///vacuole+++GO:0035749///myelin sheath adaxonal region+++GO:0016323///basolateral plasma membrane+++GO:0008021///synaptic vesicle+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0005802///trans-Golgi network+++GO:0042734///presynaptic membrane+++GO:0009986///cell surface+++GO:0048787///presynaptic active zone membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0036477///somatodendritic compartment+++GO:0000322///storage vacuole+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0045335///phagocytic vesicle+++GO:0031201///SNARE complex+++GO:0016021///integral component of membrane+++GO:0043219///lateral loop+++GO:0043197///dendritic spine+++GO:0005623///cell+++GO:0005615///extracellular space+++GO:0005737///cytoplasm","GO:0000149///SNARE binding+++GO:0016230///sphingomyelin phosphodiesterase activator activity+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding","GO:0043311///positive regulation of eosinophil degranulation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0016192///vesicle-mediated transport+++GO:0061025///membrane fusion+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0035493///SNARE complex assembly+++GO:0008284///positive regulation of cell proliferation+++GO:0048284///organelle fusion+++GO:0050921///positive regulation of chemotaxis+++GO:0060291///long-term synaptic potentiation+++GO:2000010///positive regulation of protein localization to cell surface+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0033194///response to hydroperoxide+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0043085///positive regulation of catalytic activity+++GO:0006886///intracellular protein transport+++GO:0017157///regulation of exocytosis+++GO:0006836///neurotransmitter transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0048278///vesicle docking+++GO:0045785///positive regulation of cell adhesion+++GO:0030335///positive regulation of cell migration+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0006906///vesicle fusion+++GO:0006887///exocytosis","syntaxin 4","[STX4_HUMAN|Reviewed]RecName: Full=Syntaxin-4; AltName: Full=Renal carcinoma antigen NY-REN-31;+++[A0A087WWW0_HUMAN|Unreviewed]SubName: Full=Syntaxin-4 {ECO:0000313|Ensembl:ENSP00000480544}; Flags: Fragment;+++[B7Z425_HUMAN|Unreviewed]SubName: Full=Syntaxin 4A (Placental), isoform CRA_a {ECO:0000313|EMBL:EAW52175.1}; SubName: Full=cDNA FLJ57517, highly similar to Syntaxin-4 {ECO:0000313|EMBL:BAH12411.1};+++[C9JFM5_HUMAN|Unreviewed]SubName: Full=Syntaxin-4 {ECO:0000313|Ensembl:ENSP00000390788}; Flags: Fragment;+++[H3BMK2_HUMAN|Unreviewed]SubName: Full=Syntaxin-4 {ECO:0000313|Ensembl:ENSP00000454419};"]
[6820,"'SULT2B1'",3,1,2,2,"00140///Steroid hormone biosynthesis","H00734///Autosomal recessive congenital ichthyosis",null,"R03405///3'-phosphoadenylylsulfate:alcohol sulfotransferase   3'-Phosphoadenylyl sulfate + Dehydroepiandrosterone <=> Adenosine 3',5'-bisphosphate + Dehydroepiandrosterone sulfate+++R08977///3'-phosphoadenylyl-sulfate:cholesterol sulfotransferase   Cholesterol + 3'-Phosphoadenylyl sulfate <=> Cholesterol sulfate + Adenosine 3',5'-bisphosphate+++R00629///3'-phosphoadenylyl-sulfate:alcohol sulfotransferase   Alcohol + 3'-Phosphoadenylyl sulfate <=> Alkyl sulfate + Adenosine 3',5'-bisphosphate+++R08978///3'-phosphoadenylyl-sulfate:pregnenolone sulfotransferase   Pregnenolone + 3'-Phosphoadenylyl sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + Adenosine 3',5'-bisphosphate","GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:1990239///steroid hormone binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0015485///cholesterol binding+++GO:0004027///alcohol sulfotransferase activity+++GO:0050294///steroid sulfotransferase activity+++GO:0005515///protein binding+++GO:0008146///sulfotransferase activity","GO:0008203///cholesterol metabolic process+++GO:0006629///lipid metabolic process+++GO:0000103///sulfate assimilation+++GO:0008285///negative regulation of cell proliferation+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0008202///steroid metabolic process","sulfotransferase family 2B member 1","[ST2B1_HUMAN|Reviewed]RecName: Full=Sulfotransferase family cytosolic 2B member 1; Short=ST2B1; Short=Sulfotransferase 2B1; EC=2.8.2.2; AltName: Full=Alcohol sulfotransferase; AltName: Full=Hydroxysteroid sulfotransferase 2;"]
[6855,"'SYP'",55,80,62,65.6666666666667,{"$nulls":4},"GO:0098685///Schaffer collateral - CA1 synapse+++GO:0060076///excitatory synapse+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0042734///presynaptic membrane+++GO:0044306///neuron projection terminus+++GO:0030672///synaptic vesicle membrane+++GO:0045202///synapse+++GO:0043005///neuron projection+++GO:0030054///cell junction+++GO:0043195///terminal bouton+++GO:0031594///neuromuscular junction+++GO:0008021///synaptic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0048786///presynaptic active zone+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0042802///identical protein binding+++GO:0042169///SH2 domain binding+++GO:0015485///cholesterol binding+++GO:0043621///protein self-association","GO:0048488///synaptic vesicle endocytosis+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:2000474///regulation of opioid receptor signaling pathway+++GO:0006897///endocytosis+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0071310///cellular response to organic substance+++GO:0016188///synaptic vesicle maturation+++GO:0048499///synaptic vesicle membrane organization","synaptophysin","[SYPH_HUMAN|Reviewed]RecName: Full=Synaptophysin; AltName: Full=Major synaptic vesicle protein p38;+++[F2Z3E1_HUMAN|Unreviewed]SubName: Full=Synaptophysin {ECO:0000313|Ensembl:ENSP00000418987};+++[G5E9A2_HUMAN|Unreviewed]SubName: Full=Synaptophysin, isoform CRA_a {ECO:0000313|EMBL:EAW50684.1};+++[H7C4W3_HUMAN|Unreviewed]SubName: Full=Synaptophysin {ECO:0000313|Ensembl:ENSP00000418387}; Flags: Fragment;"]
[687,"'KLF9'",1063,958,818,946.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01877///Chromosome 15q13.3 microdeletion syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0007623///circadian rhythm+++GO:0048511///rhythmic process+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0071387///cellular response to cortisol stimulus+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010839///negative regulation of keratinocyte proliferation","Kruppel like factor 9","[KLF9_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 9; AltName: Full=Basic transcription element-binding protein 1; Short=BTE-binding protein 1; AltName: Full=GC-box-binding protein 1; AltName: Full=Transcription factor BTEB1;+++[A0A024R260_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 9, isoform CRA_a {ECO:0000313|EMBL:EAW62504.1};+++[B5BUG8_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 9 {ECO:0000313|EMBL:BAG70218.1}; Flags: Fragment;"]
[6884,"'TAF13'",47,41,53,47,"05168///Herpes simplex infection+++03022///Basal transcription factors","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0005654///nucleoplasm","GO:0008022///protein C-terminus binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003712///transcription coregulator activity+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0006352///DNA-templated transcription, initiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II","TATA-box binding protein associated factor 13","[TAF13_HUMAN|Reviewed]RecName: Full=Transcription initiation factor TFIID subunit 13 {ECO:0000305}; AltName: Full=Transcription initiation factor TFIID 18 kDa subunit {ECO:0000303|PubMed:7729427}; Short=TAF(II)18 {ECO:0000303|PubMed:9695952}; Short=TAFII-18 {ECO:0000305}; Short=TAFII18 {ECO:0000303|PubMed:7729427};+++[A0A024R089_HUMAN|Unreviewed]SubName: Full=TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa, isoform CRA_a {ECO:0000313|EMBL:EAW56355.1};+++[Q0VA92_HUMAN|Unreviewed]SubName: Full=TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa {ECO:0000313|EMBL:AAI21182.1};"]
[6913,"'TBX15'",1,3,0,1.33333333333333,null,"H00873///Cousin syndrome",null,null,"GO:0005634///nucleus+++GO:0070722///Tle3-Aes complex","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048701///embryonic cranial skeleton morphogenesis","T-box 15","[TBX15_HUMAN|Reviewed]RecName: Full=T-box transcription factor TBX15; Short=T-box protein 15; AltName: Full=T-box transcription factor TBX14; Short=T-box protein 14;+++[Q5JT55_HUMAN|Unreviewed]SubName: Full=T-box transcription factor TBX15 {ECO:0000313|Ensembl:ENSP00000398625}; Flags: Fragment;+++[Q8N8P2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39077 fis, clone NT2RP7017795, highly similar to TBX15 PROTEIN {ECO:0000313|EMBL:BAC04776.1};"]
[6921,"'ELOC'",257,242,272,257,"04066///HIF-1 signaling pathway+++04120///Ubiquitin mediated proteolysis+++05200///Pathways in cancer+++05211///Renal cell carcinoma",null,"M00383///ECV complex+++M00388///ECS complex",null,"GO:0005829///cytosol+++GO:0070449///elongin complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003746///translation elongation factor activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016032///viral process+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0016567///protein ubiquitination+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0006414///translational elongation+++GO:0006366///transcription by RNA polymerase II","elongin C","[ELOC_HUMAN|Reviewed]RecName: Full=Elongin-C; Short=EloC; AltName: Full=Elongin 15 kDa subunit; AltName: Full=RNA polymerase II transcription factor SIII subunit C; AltName: Full=SIII p15; AltName: Full=Transcription elongation factor B polypeptide 1;+++[A0A024R7Y5_HUMAN|Unreviewed]SubName: Full=Transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C), isoform CRA_a {ECO:0000313|EMBL:EAW87016.1};+++[E5RHG8_HUMAN|Unreviewed]SubName: Full=Elongin-C {ECO:0000313|Ensembl:ENSP00000429789}; Flags: Fragment;+++[R4GMY8_HUMAN|Unreviewed]SubName: Full=Elongin-C {ECO:0000313|Ensembl:ENSP00000473408};"]
[6935,"'ZEB1'",393,412,366,390.333333333333,"05206///MicroRNAs in cancer","H00960///Fuchs corneal dystrophy (FECD)+++H00961///Posterior polymorphous corneal dystrophy (PPCD)+++H00908///Mowat-Wilson syndrome",null,null,"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0008134///transcription factor binding+++GO:0003682///chromatin binding+++GO:0003714///transcription corepressor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0008270///zinc ion binding+++GO:0003676///nucleic acid binding+++GO:0003713///transcription coactivator activity+++GO:0070888///E-box binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051150///regulation of smooth muscle cell differentiation+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0007417///central nervous system development+++GO:0008283///cell proliferation+++GO:0045666///positive regulation of neuron differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:0048598///embryonic morphogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045602///negative regulation of endothelial cell differentiation+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0010464///regulation of mesenchymal cell proliferation+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051216///cartilage development+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0048513///animal organ development+++GO:0006955///immune response+++GO:0071230///cellular response to amino acid stimulus+++GO:0048752///semicircular canal morphogenesis+++GO:0090103///cochlea morphogenesis","zinc finger E-box binding homeobox 1","[ZEB1_HUMAN|Reviewed]RecName: Full=Zinc finger E-box-binding homeobox 1; AltName: Full=NIL-2-A zinc finger protein; AltName: Full=Negative regulator of IL2; AltName: Full=Transcription factor 8; Short=TCF-8;+++[A0JLS9_HUMAN|Unreviewed]SubName: Full=ZEB1 protein {ECO:0000313|EMBL:AAH09572.1}; Flags: Fragment;+++[B2RBI8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95535, highly similar to Homo sapiens transcription factor 8 (represses interleukin 2 expression) (TCF8), mRNA {ECO:0000313|EMBL:BAG37235.1};+++[B4DGU2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61244, highly similar to Transcription factor 8 {ECO:0000313|EMBL:BAG57903.1};+++[F6TDF5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 1 {ECO:0000313|Ensembl:ENSP00000415961}; Flags: Fragment;+++[F6U0D0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 1 {ECO:0000313|Ensembl:ENSP00000405958};+++[H0YMD3_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 1 {ECO:0000313|Ensembl:ENSP00000453559}; Flags: Fragment;+++[H0YMN2_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 1 {ECO:0000313|Ensembl:ENSP00000453674}; Flags: Fragment;+++[H0YND9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 1 {ECO:0000313|Ensembl:ENSP00000453970}; Flags: Fragment;+++[L0R5E9_HUMAN|Unreviewed]SubName: Full=Alternative protein ZEB1 {ECO:0000313|EMBL:CCO13853.1};+++[L8EAF3_HUMAN|Unreviewed]SubName: Full=Alternative protein ZEB1 {ECO:0000313|EMBL:CCQ43736.1};+++[Q32Q63_HUMAN|Unreviewed]SubName: Full=ZEB1 protein {ECO:0000313|EMBL:AAI07782.1}; Flags: Fragment;"]
[6993,"'DYNLT1'",474,334,384,397.333333333333,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005868///cytoplasmic dynein complex+++GO:0043025///neuronal cell body+++GO:0030286///dynein complex+++GO:0030027///lamellipodium+++GO:0005881///cytoplasmic microtubule+++GO:1904813///ficolin-1-rich granule lumen+++GO:0043657///host cell+++GO:0005874///microtubule+++GO:0099503///secretory vesicle+++GO:0034774///secretory granule lumen+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0044295///axonal growth cone+++GO:0005576///extracellular region","GO:0003774///motor activity+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0048812///neuron projection morphogenesis+++GO:0016358///dendrite development+++GO:0043312///neutrophil degranulation+++GO:0051493///regulation of cytoskeleton organization+++GO:0016032///viral process+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0075521///microtubule-dependent intracellular transport of viral material towards nucleus+++GO:0075606///transport of viral material towards nucleus+++GO:0010976///positive regulation of neuron projection development+++GO:0061564///axon development+++GO:0060548///negative regulation of cell death+++GO:0007049///cell cycle+++GO:0035795///negative regulation of mitochondrial membrane permeability+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0019060///intracellular transport of viral protein in host cell+++GO:0050768///negative regulation of neurogenesis+++GO:0051301///cell division+++GO:0000132///establishment of mitotic spindle orientation+++GO:0043087///regulation of GTPase activity+++GO:0046718///viral entry into host cell+++GO:0007399///nervous system development","dynein light chain Tctex-type 1","[DYLT1_HUMAN|Reviewed]RecName: Full=Dynein light chain Tctex-type 1; AltName: Full=Protein CW-1; AltName: Full=T-complex testis-specific protein 1 homolog;"]
[7013,"'TERF1'",495,437,479.67,470.556666666667,null,null,"M00424///Shelterin complex",null,"GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0000783///nuclear telomere cap complex+++GO:0016604///nuclear body+++GO:0070187///shelterin complex+++GO:0005819///spindle+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center+++GO:0000781///chromosome, telomeric region+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005694///chromosome","GO:0042162///telomeric DNA binding+++GO:0008301///DNA binding, bending+++GO:0003720///telomerase activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0071532///ankyrin repeat binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0003677///DNA binding+++GO:0008022///protein C-terminus binding+++GO:0042803///protein homodimerization activity+++GO:0008017///microtubule binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003691///double-stranded telomeric DNA binding","GO:0008156///negative regulation of DNA replication+++GO:0031116///positive regulation of microtubule polymerization+++GO:1904911///negative regulation of establishment of RNA localization to telomere+++GO:0016233///telomere capping+++GO:1904792///positive regulation of shelterin complex assembly+++GO:0000723///telomere maintenance+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007094///mitotic spindle assembly checkpoint+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:0061820///telomeric D-loop disassembly+++GO:0032214///negative regulation of telomere maintenance via semi-conservative replication+++GO:0007049///cell cycle+++GO:0051260///protein homooligomerization+++GO:0090656///t-circle formation+++GO:0051301///cell division+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0007004///telomere maintenance via telomerase+++GO:0045141///meiotic telomere clustering+++GO:0042493///response to drug+++GO:1905839///negative regulation of telomeric D-loop disassembly+++GO:1904850///negative regulation of establishment of protein localization to telomere+++GO:0043065///positive regulation of apoptotic process+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:1904914///negative regulation of establishment of protein-containing complex localization to telomere+++GO:0051974///negative regulation of telomerase activity+++GO:1905778///negative regulation of exonuclease activity","telomeric repeat binding factor 1","[TERF1_HUMAN|Reviewed]RecName: Full=Telomeric repeat-binding factor 1; AltName: Full=NIMA-interacting protein 2; AltName: Full=TTAGGG repeat-binding factor 1; AltName: Full=Telomeric protein Pin2/TRF1;+++[A0A024R7X1_HUMAN|Unreviewed]RecName: Full=Telomeric repeat-binding factor {ECO:0000256|PIRNR:PIRNR038016};+++[A0A024R7X2_HUMAN|Unreviewed]RecName: Full=Telomeric repeat-binding factor {ECO:0000256|PIRNR:PIRNR038016};+++[E5RFJ5_HUMAN|Unreviewed]SubName: Full=Telomeric repeat-binding factor 1 {ECO:0000313|Ensembl:ENSP00000428838}; Flags: Fragment;+++[E7EWM7_HUMAN|Unreviewed]SubName: Full=Telomeric repeat-binding factor 1 {ECO:0000313|Ensembl:ENSP00000430121}; Flags: Fragment;"]
[7030,"'TFE3'",2081,1890,1919,1963.33333333333,"05202///Transcriptional misregulation in cancer+++05211///Renal cell carcinoma+++04137///Mitophagy - animal","H00051///Alveolar soft part sarcoma+++H00021///Renal cell carcinoma",null,null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006959///humoral immune response+++GO:0045785///positive regulation of cell adhesion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045670///regulation of osteoclast differentiation+++GO:0002376///immune system process+++GO:0002250///adaptive immune response","transcription factor binding to IGHM enhancer 3","[TFE3_HUMAN|Reviewed]RecName: Full=Transcription factor E3; AltName: Full=Class E basic helix-loop-helix protein 33; Short=bHLHe33;+++[A0A024QZ23_HUMAN|Unreviewed]SubName: Full=Transcription factor binding to IGHM enhancer 3, isoform CRA_a {ECO:0000313|EMBL:EAW50712.1};+++[B4DIA5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59531, highly similar to Transcription factor E3 {ECO:0000313|EMBL:BAG58417.1};"]
[7054,"'TH'",6,5,2,4.33333333333333,"01110///Biosynthesis of secondary metabolites+++05030///Cocaine addiction+++05034///Alcoholism+++04728///Dopaminergic synapse+++00790///Folate biosynthesis+++01100///Metabolic pathways+++00950///Isoquinoline alkaloid biosynthesis+++05012///Parkinson's disease+++04917///Prolactin signaling pathway+++05031///Amphetamine addiction+++00350///Tyrosine metabolism","H00831///Primary dystonia","M00042///Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline","R07212///L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase(3-hydroxylating)   L-Tyrosine + Tetrahydrobiopterin + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + 4a-Hydroxytetrahydrobiopterin+++R01815///L-Tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)   Tetrahydrobiopterin + L-Tyrosine + Oxygen <=> 3,4-Dihydroxy-L-phenylalanine + Dihydrobiopterin + H2O","GO:0005739///mitochondrion+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0005634///nucleus+++GO:0030659///cytoplasmic vesicle membrane+++GO:0043025///neuronal cell body+++GO:0031410///cytoplasmic vesicle+++GO:0033162///melanosome membrane+++GO:0043204///perikaryon+++GO:0005737///cytoplasm+++GO:0005790///smooth endoplasmic reticulum+++GO:0043195///terminal bouton+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0008021///synaptic vesicle","GO:0034617///tetrahydrobiopterin binding+++GO:0008198///ferrous iron binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016597///amino acid binding+++GO:0005506///iron ion binding+++GO:0004511///tyrosine 3-monooxygenase activity+++GO:0008199///ferric iron binding+++GO:0016714///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen+++GO:0019825///oxygen binding+++GO:0019904///protein domain specific binding+++GO:0019899///enzyme binding+++GO:0046872///metal ion binding+++GO:0035240///dopamine binding+++GO:0004497///monooxygenase activity","GO:0042214///terpene metabolic process+++GO:0015842///aminergic neurotransmitter loading into synaptic vesicle+++GO:0007612///learning+++GO:0003007///heart morphogenesis+++GO:0007507///heart development+++GO:0046684///response to pyrethroid+++GO:0009651///response to salt stress+++GO:0006585///dopamine biosynthetic process from tyrosine+++GO:0071287///cellular response to manganese ion+++GO:0070848///response to growth factor+++GO:0052314///phytoalexin metabolic process+++GO:0010259///multicellular organism aging+++GO:0001963///synaptic transmission, dopaminergic+++GO:0035690///cellular response to drug+++GO:0071316///cellular response to nicotine+++GO:0035900///response to isolation stress+++GO:0007605///sensory perception of sound+++GO:0021987///cerebral cortex development+++GO:0010038///response to metal ion+++GO:0071333///cellular response to glucose stimulus+++GO:0042755///eating behavior+++GO:0048545///response to steroid hormone+++GO:0071363///cellular response to growth factor stimulus+++GO:0042745///circadian sleep/wake cycle+++GO:0009416///response to light stimulus+++GO:0050890///cognition+++GO:0009887///animal organ morphogenesis+++GO:0001975///response to amphetamine+++GO:0042418///epinephrine biosynthetic process+++GO:0042421///norepinephrine biosynthetic process+++GO:0014070///response to organic cyclic compound+++GO:0008016///regulation of heart contraction+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0042493///response to drug+++GO:0042423///catecholamine biosynthetic process+++GO:0045472///response to ether+++GO:0009414///response to water deprivation+++GO:0051412///response to corticosterone+++GO:0035902///response to immobilization stress+++GO:0055114///oxidation-reduction process+++GO:0006665///sphingolipid metabolic process+++GO:0010043///response to zinc ion+++GO:0035176///social behavior+++GO:0006631///fatty acid metabolic process+++GO:0045471///response to ethanol+++GO:0043434///response to peptide hormone+++GO:0009635///response to herbicide+++GO:0043473///pigmentation+++GO:0014823///response to activity+++GO:0032496///response to lipopolysaccharide+++GO:0001666///response to hypoxia+++GO:0042462///eye photoreceptor cell development+++GO:0031667///response to nutrient levels+++GO:0042416///dopamine biosynthetic process+++GO:0007626///locomotory behavior+++GO:0033076///isoquinoline alkaloid metabolic process+++GO:0032355///response to estradiol+++GO:0042136///neurotransmitter biosynthetic process+++GO:0035094///response to nicotine+++GO:0009072///aromatic amino acid family metabolic process+++GO:0007613///memory+++GO:0051602///response to electrical stimulus+++GO:0018963///phthalate metabolic process+++GO:0007617///mating behavior+++GO:0017085///response to insecticide+++GO:0007601///visual perception+++GO:0016137///glycoside metabolic process+++GO:0071312///cellular response to alkaloid+++GO:0009653///anatomical structure morphogenesis","tyrosine hydroxylase","[TY3H_HUMAN|Reviewed]RecName: Full=Tyrosine 3-monooxygenase; EC=1.14.16.2; AltName: Full=Tyrosine 3-hydroxylase; Short=TH;+++[E7EQI0_HUMAN|Unreviewed]SubName: Full=Tyrosine 3-monooxygenase {ECO:0000313|Ensembl:ENSP00000370560};+++[F8W8M5_HUMAN|Unreviewed]SubName: Full=Tyrosine 3-monooxygenase {ECO:0000313|Ensembl:ENSP00000325831};+++[H0Y670_HUMAN|Unreviewed]SubName: Full=Tyrosine 3-monooxygenase {ECO:0000313|Ensembl:ENSP00000403440}; Flags: Fragment;+++[H0Y677_HUMAN|Unreviewed]SubName: Full=Tyrosine 3-monooxygenase {ECO:0000313|Ensembl:ENSP00000403546}; Flags: Fragment;+++[P78428_HUMAN|Unreviewed]SubName: Full=Tyrosine hydroxylase {ECO:0000313|EMBL:AAA61172.1}; Flags: Fragment;+++[Q7KZ36_HUMAN|Unreviewed]SubName: Full=Tyrosine hydroxylase {ECO:0000313|EMBL:AAA61171.1}; Flags: Fragment;+++[Q7KZ38_HUMAN|Unreviewed]SubName: Full=Tyrosine hydroxylase {ECO:0000313|EMBL:AAA77650.1}; EC=1.14.16.2 {ECO:0000313|EMBL:AAA77650.1}; Flags: Fragment;+++[Q7KZ39_HUMAN|Unreviewed]SubName: Full=Tyrosine hydroxylase {ECO:0000313|EMBL:AAA77651.1}; EC=1.14.16.2 {ECO:0000313|EMBL:AAA77651.1}; Flags: Fragment;+++[Q7KZ44_HUMAN|Unreviewed]SubName: Full=TH protein {ECO:0000313|EMBL:AAA61168.1}; Flags: Fragment;+++[Q9UQ57_HUMAN|Unreviewed]SubName: Full=Tyrosine hydroxylase {ECO:0000313|EMBL:AAA77649.1}; EC=1.14.16.2 {ECO:0000313|EMBL:AAA77649.1}; Flags: Fragment;"]
[7071,"'KLF10'",1716,1327,1395,1479.33333333333,null,"H00410///Maturity onset diabetes of the young (MODY)",null,null,"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0045672///positive regulation of osteoclast differentiation+++GO:1901653///cellular response to peptide+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030282///bone mineralization+++GO:0001501///skeletal system development+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0035019///somatic stem cell population maintenance+++GO:0007623///circadian rhythm+++GO:0048511///rhythmic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007267///cell-cell signaling+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042752///regulation of circadian rhythm+++GO:0009267///cellular response to starvation+++GO:0008283///cell proliferation","Kruppel like factor 10","[KLF10_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 10; AltName: Full=EGR-alpha; AltName: Full=Transforming growth factor-beta-inducible early growth response protein 1; Short=TGFB-inducible early growth response protein 1; Short=TIEG-1;"]
[7092,"'TLL1'",103,69,77,83,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00546///Atrial septal defect",null,null,"GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008237///metallopeptidase activity","GO:0001501///skeletal system development+++GO:0022617///extracellular matrix disassembly+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0006508///proteolysis","tolloid like 1","[TLL1_HUMAN|Reviewed]RecName: Full=Tolloid-like protein 1; EC=3.4.24.-; Flags: Precursor;+++[B7ZLW3_HUMAN|Unreviewed]RecName: Full=Metalloendopeptidase {ECO:0000256|RuleBase:RU361183}; EC=3.4.24.- {ECO:0000256|RuleBase:RU361183};+++[D6RAK5_HUMAN|Unreviewed]SubName: Full=Tolloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000421732};+++[D6RBI6_HUMAN|Unreviewed]SubName: Full=Tolloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000422692};+++[D6RCE0_HUMAN|Unreviewed]SubName: Full=Tolloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000423748}; Flags: Fragment;+++[E9PD25_HUMAN|Unreviewed]RecName: Full=Metalloendopeptidase {ECO:0000256|RuleBase:RU361183}; EC=3.4.24.- {ECO:0000256|RuleBase:RU361183};"]
[7105,"'TSPAN6'",583,457,499,513,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome","GO:0005515///protein binding","GO:0007166///cell surface receptor signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0039532///negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway","tetraspanin 6","[TSN6_HUMAN|Reviewed]RecName: Full=Tetraspanin-6; Short=Tspan-6; AltName: Full=A15 homolog; AltName: Full=Putative NF-kappa-B-activating protein 321; AltName: Full=T245 protein; AltName: Full=Tetraspanin TM4-D; AltName: Full=Transmembrane 4 superfamily member 6;+++[A0A024RCI0_HUMAN|Unreviewed]SubName: Full=Tetraspanin 6, isoform CRA_a {ECO:0000313|EMBL:EAX02810.1};+++[A0A087WYV6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-6 {ECO:0000313|Ensembl:ENSP00000482130};+++[A0A087WZU5_HUMAN|Unreviewed]SubName: Full=Tetraspanin-6 {ECO:0000313|Ensembl:ENSP00000482894};"]
[7128,"'TNFAIP3'",235,277,301,271,"04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++05169///Epstein-Barr virus infection+++04064///NF-kappa B signaling pathway+++05162///Measles+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway","H01492///Systemic sclerosis",null,null,"GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0043621///protein self-association+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0019900///kinase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0043130///ubiquitin binding+++GO:0008234///cysteine-type peptidase activity+++GO:0003824///catalytic activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0002020///protease binding","GO:0071108///protein K48-linked deubiquitination+++GO:0072573///tolerance induction to lipopolysaccharide+++GO:1990168///protein K33-linked deubiquitination+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0032480///negative regulation of type I interferon production+++GO:0032715///negative regulation of interleukin-6 production+++GO:0006954///inflammatory response+++GO:0050869///negative regulation of B cell activation+++GO:0001922///B-1 B cell homeostasis+++GO:0032691///negative regulation of interleukin-1 beta production+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0008152///metabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0034148///negative regulation of toll-like receptor 5 signaling pathway+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0035871///protein K11-linked deubiquitination+++GO:0031397///negative regulation of protein ubiquitination+++GO:0045824///negative regulation of innate immune response+++GO:0032495///response to muramyl dipeptide+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:2000349///negative regulation of CD40 signaling pathway+++GO:0070429///negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0050691///regulation of defense response to virus by host+++GO:0002634///regulation of germinal center formation+++GO:0035523///protein K29-linked deubiquitination+++GO:0050713///negative regulation of interleukin-1 beta secretion+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0060548///negative regulation of cell death+++GO:0051259///protein complex oligomerization+++GO:0070936///protein K48-linked ubiquitination+++GO:0072666///establishment of protein localization to vacuole+++GO:0071947///protein deubiquitination involved in ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0090291///negative regulation of osteoclast proliferation+++GO:0002237///response to molecule of bacterial origin+++GO:0045779///negative regulation of bone resorption+++GO:0034140///negative regulation of toll-like receptor 3 signaling pathway+++GO:0032703///negative regulation of interleukin-2 production+++GO:0050728///negative regulation of inflammatory response+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0007010///cytoskeleton organization+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0070536///protein K63-linked deubiquitination+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0006508///proteolysis+++GO:0070433///negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0002677///negative regulation of chronic inflammatory response+++GO:0070301///cellular response to hydrogen peroxide+++GO:0016579///protein deubiquitination+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0061043///regulation of vascular wound healing+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:0016477///cell migration","TNF alpha induced protein 3","[TNAP3_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor alpha-induced protein 3; Short=TNF alpha-induced protein 3; EC=2.3.2.-; EC=3.4.19.12 {ECO:0000269|PubMed:14748687, ECO:0000269|PubMed:17961127, ECO:0000269|PubMed:18164316, ECO:0000269|PubMed:23827681, ECO:0000269|PubMed:27732584}; AltName: Full=OTU domain-containing protein 7C; AltName: Full=Putative DNA-binding protein A20; AltName: Full=Zinc finger protein A20; Contains: RecName: Full=A20p50; Contains: RecName: Full=A20p37;+++[A0A087WU80_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000478438};+++[A0A087WVN3_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000479556};+++[A0A087WXL5_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000481122};+++[A0A087X1N1_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000484332};+++[D3TTY4_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87230.1};+++[D3TTY5_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87231.1}; SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000481454};+++[D3TTY6_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87232.1};+++[D3TTY7_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87233.1};+++[D3TTY8_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87234.1};+++[D3TTY9_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87235.1};+++[D3TTZ0_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87236.1};+++[D3TTZ1_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87237.1};+++[D3TTZ2_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87238.1};+++[D3TTZ3_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87239.1};+++[D3TTZ4_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87240.1};+++[D3TTZ5_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87241.1};+++[D3TTZ6_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87242.1};+++[D3TTZ7_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87243.1};+++[D3TTZ8_HUMAN|Unreviewed]SubName: Full=Truncated tumor necrosis factor alpha-induced protein 3 {ECO:0000313|EMBL:ACN87244.1};+++[F8K9X7_HUMAN|Unreviewed]SubName: Full=TNFAIP3 (A20) {ECO:0000313|EMBL:CBY94061.1}; Flags: Fragment;+++[Q5VXQ8_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000401562}; Flags: Fragment;+++[Q5VXQ9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000409845}; Flags: Fragment;+++[Q5VXR0_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 3 {ECO:0000313|Ensembl:ENSP00000393577}; Flags: Fragment;"]
[7157,"'TP53'",1273,1380,1332,1328.33333333333,"05161///Hepatitis B+++05224///Breast cancer+++05212///Pancreatic cancer+++05223///Non-small cell lung cancer+++04218///Cellular senescence+++04115///p53 signaling pathway+++05163///Human cytomegalovirus infection+++05213///Endometrial cancer+++04210///Apoptosis+++05206///MicroRNAs in cancer+++04919///Thyroid hormone signaling pathway+++05222///Small cell lung cancer+++04722///Neurotrophin signaling pathway+++05162///Measles+++05210///Colorectal cancer+++05230///Central carbon metabolism in cancer+++04137///Mitophagy - animal+++05200///Pathways in cancer+++05169///Epstein-Barr virus infection+++04071///Sphingolipid signaling pathway+++04110///Cell cycle+++05166///HTLV-I infection+++05220///Chronic myeloid leukemia+++05216///Thyroid cancer+++05217///Basal cell carcinoma+++05226///Gastric cancer+++05214///Glioma+++05160///Hepatitis C+++05016///Huntington's disease+++04211///Longevity regulating pathway+++01524///Platinum drug resistance+++05218///Melanoma+++05418///Fluid shear stress and atherosclerosis+++05205///Proteoglycans in cancer+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++04216///Ferroptosis+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05014///Amyotrophic lateral sclerosis (ALS)+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis+++01522///Endocrine resistance+++04310///Wnt signaling pathway+++05215///Prostate cancer+++05219///Bladder cancer+++05225///Hepatocellular carcinoma+++04010///MAPK signaling pathway+++05168///Herpes simplex infection","H00033///Adrenal carcinoma+++H00026///Endometrial cancer+++H00005///Chronic lymphocytic leukemia (CLL)+++H00044///Cancer of the anal canal+++H00006///Hairy-cell leukemia+++H01007///Choroid plexus papilloma+++H00014///Non-small cell lung cancer+++H00025///Penile cancer+++H00881///Li-Fraumeni syndrome+++H01554///Fallopian tube cancer+++H00041///Kaposi's sarcoma+++H00016///Oral cancer+++H00055///Laryngeal cancer+++H01463///Mycosis fungoides+++H00022///Bladder cancer+++H00040///Squamous cell carcinoma+++H00015///Malignant pleural mesothelioma+++H01481///Myelodysplastic syndrome (MDS)+++H00042///Glioma+++H00008///Burkitt lymphoma+++H00038///Melanoma+++H00036///Osteosarcoma+++H00028///Choriocarcinoma+++H00047///Gallbladder cancer+++H00027///Ovarian cancer+++H00032///Thyroid cancer+++H00020///Colorectal cancer+++H00018///Gastric cancer+++H00010///Multiple myeloma+++H01470///Giant cell tumor of bone+++H01559///Oropharyngeal cancer+++H00031///Breast cancer+++H00004///Chronic myeloid leukemia (CML)+++H00009///Adult T-cell leukemia+++H00029///Vulvar cancer+++H01557///Hepatic angiosarcoma+++H00046///Cholangiocarcinoma+++H00013///Small cell lung cancer+++H00039///Basal cell carcinoma+++H01464///Mantle cell lymphoma+++H00019///Pancreatic cancer+++H01667///Medulloblastoma+++H01555///Merkel cell carcinoma+++H00017///Esophageal cancer+++H00048///Hepatocellular carcinoma",null,null,"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005669///transcription factor TFIID complex+++GO:0005759///mitochondrial matrix+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0000790///nuclear chromatin+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0005622///intracellular+++GO:0016363///nuclear matrix+++GO:0005739///mitochondrion+++GO:0016605///PML body+++GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0002039///p53 binding+++GO:0051721///protein phosphatase 2A binding+++GO:0042802///identical protein binding+++GO:0002020///protease binding+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008270///zinc ion binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0047485///protein N-terminus binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0051087///chaperone binding+++GO:0005524///ATP binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019903///protein phosphatase binding+++GO:0019899///enzyme binding+++GO:0042826///histone deacetylase binding+++GO:0008134///transcription factor binding+++GO:0043621///protein self-association+++GO:0003730///mRNA 3'-UTR binding+++GO:0005507///copper ion binding+++GO:0035035///histone acetyltransferase binding+++GO:0001094///TFIID-class transcription factor complex binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0003677///DNA binding+++GO:1990841///promoter-specific chromatin binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0046872///metal ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding+++GO:0019901///protein kinase binding+++GO:0003682///chromatin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003700///DNA-binding transcription factor activity","GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0006983///ER overload response+++GO:0012501///programmed cell death+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0006915///apoptotic process+++GO:0034644///cellular response to UV+++GO:0006284///base-excision repair+++GO:0051097///negative regulation of helicase activity+++GO:0072717///cellular response to actinomycin D+++GO:0051974///negative regulation of telomerase activity+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0035690///cellular response to drug+++GO:0051262///protein tetramerization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0006289///nucleotide-excision repair+++GO:0008285///negative regulation of cell proliferation+++GO:0008340///determination of adult lifespan+++GO:0007275///multicellular organism development+++GO:0007050///cell cycle arrest+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0030308///negative regulation of cell growth+++GO:0071479///cellular response to ionizing radiation+++GO:0065003///protein-containing complex assembly+++GO:0016032///viral process+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0072331///signal transduction by p53 class mediator+++GO:0006355///regulation of transcription, DNA-templated+++GO:0034613///cellular protein localization+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0007265///Ras protein signal transduction+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008104///protein localization+++GO:0007049///cell cycle+++GO:1902749///regulation of cell cycle G2/M phase transition+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0043066///negative regulation of apoptotic process+++GO:0000733///DNA strand renaturation+++GO:0048512///circadian behavior+++GO:0042981///regulation of apoptotic process+++GO:0071158///positive regulation of cell cycle arrest+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:0051289///protein homotetramerization+++GO:0043065///positive regulation of apoptotic process+++GO:0071456///cellular response to hypoxia+++GO:0097252///oligodendrocyte apoptotic process+++GO:0090399///replicative senescence+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0042149///cellular response to glucose starvation+++GO:0048511///rhythmic process+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0010628///positive regulation of gene expression+++GO:0010332///response to gamma radiation+++GO:0009299///mRNA transcription+++GO:0090403///oxidative stress-induced premature senescence+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0071480///cellular response to gamma radiation+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0006914///autophagy+++GO:0031497///chromatin assembly+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0032461///positive regulation of protein oligomerization+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:0046677///response to antibiotic+++GO:0016579///protein deubiquitination+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0046827///positive regulation of protein export from nucleus+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007569///cell aging","tumor protein p53","[P53_HUMAN|Reviewed]RecName: Full=Cellular tumor antigen p53; AltName: Full=Antigen NY-CO-13; AltName: Full=Phosphoprotein p53; AltName: Full=Tumor suppressor p53;+++[A0A087WT22_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[A0A087WXZ1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[A0A087WZU8_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[A0A087X1Q1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[A0A0A0U7X4_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A0M4B4Y9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A0R9RRX7_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ALD10296.1}; Flags: Fragment;+++[A0A0U1RQC9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[A0A1B1PFC7_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ANT46060.1}; Flags: Fragment;+++[A0A1B1PFD4_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ANT46062.1}; Flags: Fragment;+++[A0A1D8V7A7_HUMAN|Unreviewed]SubName: Full=TP53 {ECO:0000313|EMBL:AOX22942.1}; Flags: Fragment;+++[A0A218MJB0_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A218MJC8_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A218MJD5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A218MJD9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A218MJE1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A218MJE5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A0A218MJF3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A2I9Y7_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ABM69022.1}; Flags: Fragment;+++[A2I9Z0_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ABM69025.1}; Flags: Fragment;+++[A2I9Z1_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ABM69026.1}; Flags: Fragment;+++[A2I9Z2_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ABM69027.1}; Flags: Fragment;+++[A4GW67_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A4GW74_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A4GW75_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A4GW76_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A4GW97_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A4GWB4_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A4GWB5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[A4GWB8_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ABO28415.1}; Flags: Fragment;+++[A4GWD0_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ABO28427.1}; Flags: Fragment;+++[B1PZ15_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 {ECO:0000313|EMBL:ACA79923.1}; Flags: Fragment;+++[B4XAK8_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ABV21350.1}; Flags: Fragment;+++[B4XAL0_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ABV21352.1}; Flags: Fragment;+++[B5AKF5_HUMAN|Unreviewed]SubName: Full=Mutant p53 tumor suppressor {ECO:0000313|EMBL:ACF94999.1}; Flags: Fragment;+++[B5AKF6_HUMAN|Unreviewed]SubName: Full=Mutant p53 tumor suppressor {ECO:0000313|EMBL:ACF95000.1}; Flags: Fragment;+++[B5AKF7_HUMAN|Unreviewed]SubName: Full=Mutant p53 tumor suppressor {ECO:0000313|EMBL:ACF95001.1}; Flags: Fragment;+++[D5KL86_HUMAN|Unreviewed]SubName: Full=Truncated p53 {ECO:0000313|EMBL:ADE43214.1}; Flags: Fragment;+++[D5KL87_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ADE43215.1}; Flags: Fragment;+++[D5KL88_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ADE43216.1}; Flags: Fragment;+++[D5KL89_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ADE43217.1}; Flags: Fragment;+++[D5KL90_HUMAN|Unreviewed]SubName: Full=p53 {ECO:0000313|EMBL:ADE43218.1}; Flags: Fragment;+++[E2G6R5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[E5RMA8_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[E7EMR6_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[E7EQX7_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[E7ESS1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[E9PCY9_HUMAN|Unreviewed]SubName: Full=Cellular tumor antigen p53 {ECO:0000313|Ensembl:ENSP00000426252}; Flags: Fragment;+++[E9PFT5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[H2EHT1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[I3L0W9_HUMAN|Unreviewed]SubName: Full=Cellular tumor antigen p53 {ECO:0000313|Ensembl:ENSP00000458393}; Flags: Fragment;+++[J3KP33_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[K7PPA8_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[K7PPU4_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[L0ENF7_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ENG6_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ENG9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EP82_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EP99_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EPV7_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EPW3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EPX4_HUMAN|Unreviewed]SubName: Full=Tumor suppressor p53 {ECO:0000313|EMBL:AGA63234.1}; Flags: Fragment;+++[L0EPY0_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EPZ1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQ03_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQ05_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQ52_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQ89_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQ92_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQE2_HUMAN|Unreviewed]SubName: Full=Tumor suppressor p53 {ECO:0000313|EMBL:AGA63434.1}; Flags: Fragment;+++[L0EQJ1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQP1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQP9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQQ9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQS1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQT1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQU5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQV3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQX3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQX9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0EQY4_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ERB4_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ERI9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ERJ3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ERK8_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ERL2_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ERS6_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ES54_HUMAN|Unreviewed]SubName: Full=Tumor suppressor p53 {ECO:0000313|EMBL:AGA63405.1}; Flags: Fragment;+++[L0ES73_HUMAN|Unreviewed]SubName: Full=Tumor suppressor p53 {ECO:0000313|EMBL:AGA63430.1}; Flags: Fragment;+++[L0ES92_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[L0ESB7_HUMAN|Unreviewed]SubName: Full=Tumor suppressor p53 {ECO:0000313|EMBL:AGA63258.1}; Flags: Fragment;+++[L0ESQ5_HUMAN|Unreviewed]SubName: Full=Tumor suppressor p53 {ECO:0000313|EMBL:AGA63428.1}; Flags: Fragment;+++[Q0ZAJ9_HUMAN|Unreviewed]SubName: Full=p53-Ex10 isoform {ECO:0000313|EMBL:ABG49482.1}; Flags: Fragment;+++[Q0ZAK0_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[Q0ZAK1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[Q19RW5_HUMAN|Unreviewed]SubName: Full=Truncated p53 splice variant {ECO:0000313|EMBL:ABF61800.1}; Flags: Fragment;+++[Q19RW6_HUMAN|Unreviewed]SubName: Full=Truncated p53 {ECO:0000313|EMBL:ABF61799.1}; Flags: Fragment;+++[Q1HGV0_HUMAN|Unreviewed]SubName: Full=Mutant p53 tumor suppressor {ECO:0000313|EMBL:ABF51619.1}; Flags: Fragment;+++[Q1HGV1_HUMAN|Unreviewed]SubName: Full=Mutant p53 tumor suppressor {ECO:0000313|EMBL:ABF51618.1}; Flags: Fragment;+++[Q1HGV2_HUMAN|Unreviewed]SubName: Full=Mutant p53 tumor suppressor {ECO:0000313|EMBL:ABF51617.1}; Flags: Fragment;+++[Q1HGV3_HUMAN|Unreviewed]SubName: Full=Mutant p53 tumor suppressor {ECO:0000313|EMBL:ABF51616.1}; Flags: Fragment;+++[Q1MSW8_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[Q1MSW9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[Q1MSX0_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[Q2XSC7_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[Q53GA5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S4R334_HUMAN|Unreviewed]SubName: Full=Cellular tumor antigen p53 {ECO:0000313|Ensembl:ENSP00000473895}; Flags: Fragment;+++[S5LJ04_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LJ49_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LJ61_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LMC6_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LME3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LMG1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LMI5_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LQQ1_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LQU3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LQU8_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5LQX7_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5M207_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5M224_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5M706_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[S5M713_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304}; Flags: Fragment;+++[U6BGT3_HUMAN|Unreviewed]SubName: Full=Truncated TP53 {ECO:0000313|EMBL:AHA34180.1}; Flags: Fragment;+++[U6BHT9_HUMAN|Unreviewed]SubName: Full=TP53 {ECO:0000313|EMBL:AHA34178.1}; Flags: Fragment;+++[U6BHU6_HUMAN|Unreviewed]SubName: Full=TP53 {ECO:0000313|EMBL:AHA34183.1}; Flags: Fragment;+++[U6BI14_HUMAN|Unreviewed]SubName: Full=TP53 {ECO:0000313|EMBL:AHA34179.1}; Flags: Fragment;+++[U6BKV7_HUMAN|Unreviewed]SubName: Full=TP53 {ECO:0000313|EMBL:AHA34182.1}; Flags: Fragment;"]
[7172,"'TPMT'",220,173.94,185,192.98,"00983///Drug metabolism - other enzymes","H00964///Thiopurine S-methyltransferase deficiency (TPMT deficiency)",null,"R08239///S-adenosyl-L-methionine:6-thioinosine 5'-monophosphate S-methyltransferase   6-Thioinosine-5'-monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + S-Adenosyl-L-homocysteine+++R08246///S-adenosyl-L-methionine:6-thioguanosine monophosphate S-methyltransferase   6-Thioguanosine monophosphate + S-Adenosyl-L-methionine <=> 6-Methylthioguanosine monophosphate + S-Adenosyl-L-homocysteine+++R08236///S-adenosyl-L-methionine:6-mercaptopurin S-methyltransferase   6-Mercaptopurine + S-Adenosyl-L-methionine <=> 6-Methylmercaptopurine + S-Adenosyl-L-homocysteine","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:1904047///S-adenosyl-L-methionine binding+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0008119///thiopurine S-methyltransferase activity","GO:0032259///methylation+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0017144///drug metabolic process","thiopurine S-methyltransferase","[TPMT_HUMAN|Reviewed]RecName: Full=Thiopurine S-methyltransferase {ECO:0000303|PubMed:18484748}; EC=2.1.1.67 {ECO:0000269|PubMed:18484748, ECO:0000269|PubMed:657528}; AltName: Full=Thiopurine methyltransferase {ECO:0000303|PubMed:657528};+++[A0A024QZW0_HUMAN|Unreviewed]SubName: Full=Thiopurine S-methyltransferase, isoform CRA_d {ECO:0000313|EMBL:EAW55397.1};+++[Q9BS45_HUMAN|Unreviewed]SubName: Full=Thiopurine S-methyltransferase {ECO:0000313|EMBL:AAH05339.1};"]
[72,"'ACTG2'",397,328,242,322.333333333333,"04270///Vascular smooth muscle contraction","H01869///Megacystis microcolon intestinal hypoperistalsis syndrome",null,null,"GO:0072562///blood microparticle+++GO:0030175///filopodium+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0044297///cell body+++GO:0005737///cytoplasm+++GO:0071944///cell periphery+++GO:0030027///lamellipodium+++GO:0032982///myosin filament+++GO:0070062///extracellular exosome","GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0010628///positive regulation of gene expression+++GO:0006936///muscle contraction+++GO:0090131///mesenchyme migration","actin, gamma 2, smooth muscle, enteric","[ACTH_HUMAN|Reviewed]RecName: Full=Actin, gamma-enteric smooth muscle; AltName: Full=Alpha-actin-3; AltName: Full=Gamma-2-actin; AltName: Full=Smooth muscle gamma-actin; Contains: RecName: Full=Actin, gamma-enteric smooth muscle, intermediate form; Flags: Precursor;+++[B8ZZJ2_HUMAN|Unreviewed]SubName: Full=Actin, gamma-enteric smooth muscle {ECO:0000313|Ensembl:ENSP00000387182};+++[C9JFL5_HUMAN|Unreviewed]SubName: Full=Actin, gamma-enteric smooth muscle {ECO:0000313|Ensembl:ENSP00000410020}; Flags: Fragment;+++[F8WB63_HUMAN|Unreviewed]SubName: Full=Actin, gamma-enteric smooth muscle {ECO:0000313|Ensembl:ENSP00000410706};+++[F8WCH0_HUMAN|Unreviewed]SubName: Full=Actin, gamma-enteric smooth muscle {ECO:0000313|Ensembl:ENSP00000392894};"]
[723790,"'HIST2H2AA4'",52,54.45,53.85,53.4333333333333,"04217///Necroptosis+++05322///Systemic lupus erythematosus+++05034///Alcoholism",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006342///chromatin silencing","histone cluster 2 H2A family member a4","[H2A2A_HUMAN|Reviewed]RecName: Full=Histone H2A type 2-A; AltName: Full=Histone H2A.2; AltName: Full=Histone H2A/o;"]
[7268,"'TTC4'",258,252,239,249.666666666667,{"$nulls":5},"GO:0005515///protein binding",null,"tetratricopeptide repeat domain 4","[TTC4_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 4; Short=TPR repeat protein 4;"]
[727897,"'MUC5B'",1,0,0,0.333333333333333,"04657///IL-17 signaling pathway+++04970///Salivary secretion","H01299///Idiopathic pulmonary fibrosis",null,null,"GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0005796///Golgi lumen+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding","GO:0008150///biological_process+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0016266///O-glycan processing","mucin 5B, oligomeric mucus/gel-forming","[MUC5B_HUMAN|Reviewed]RecName: Full=Mucin-5B; Short=MUC-5B; AltName: Full=Cervical mucin; AltName: Full=High molecular weight salivary mucin MG1; AltName: Full=Mucin-5 subtype B, tracheobronchial; AltName: Full=Sublingual gland mucin; Flags: Precursor;+++[H0YDX8_HUMAN|Unreviewed]SubName: Full=Mucin-5B {ECO:0000313|Ensembl:ENSP00000434539}; Flags: Fragment;+++[Q14879_HUMAN|Unreviewed]SubName: Full=Mucin {ECO:0000313|EMBL:CAA52408.1}; Flags: Fragment;+++[Q14880_HUMAN|Unreviewed]SubName: Full=Mucin {ECO:0000313|EMBL:CAA52909.1}; Flags: Fragment;+++[Q14882_HUMAN|Unreviewed]SubName: Full=Mucin {ECO:0000313|EMBL:CAA52911.1}; Flags: Fragment;+++[Q93043_HUMAN|Unreviewed]SubName: Full=MG1 {ECO:0000313|EMBL:AAB35930.1}; Flags: Fragment;"]
[728294,"'D2HGDH'",269,362,325,318.666666666667,null,"H01225///D-2-hydroxyglutaric aciduria (D-2-HGA)",null,null,"GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0003824///catalytic activity+++GO:0004458///D-lactate dehydrogenase (cytochrome) activity+++GO:0071949///FAD binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051990///(R)-2-hydroxyglutarate dehydrogenase activity+++GO:0016491///oxidoreductase activity","GO:0022904///respiratory electron transport chain+++GO:0010042///response to manganese ion+++GO:0032026///response to magnesium ion+++GO:0051592///response to calcium ion+++GO:0032025///response to cobalt ion+++GO:0044267///cellular protein metabolic process+++GO:0010043///response to zinc ion+++GO:0055114///oxidation-reduction process+++GO:0019516///lactate oxidation+++GO:0006103///2-oxoglutarate metabolic process","D-2-hydroxyglutarate dehydrogenase","[D2HDH_HUMAN|Reviewed]RecName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial; EC=1.1.99.-; Flags: Precursor;+++[B3KSR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36830 fis, clone ASTRO2010582, highly similar to D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|EMBL:BAG52828.1};+++[B4E3K7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56310, highly similar to D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|EMBL:BAG65519.1};+++[B5MCV2_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000384723};+++[F8WCF9_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000400212};+++[G5E9E8_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, isoform CRA_b {ECO:0000313|EMBL:EAW71291.1}; SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000383580};+++[H7BZ32_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000387479}; Flags: Fragment;+++[H7C021_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000392602}; Flags: Fragment;+++[H7C0N1_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000395837}; Flags: Fragment;+++[H7C290_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000404596}; Flags: Fragment;+++[H7C3L2_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000412511}; Flags: Fragment;"]
[728568,"'C12orf73'",86,77,90,84.3333333333333,"04915///Estrogen signaling pathway+++04151///PI3K-Akt signaling pathway+++04626///Plant-pathogen interaction+++05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04918///Thyroid hormone synthesis+++04657///IL-17 signaling pathway+++04141///Protein processing in endoplasmic reticulum+++05215///Prostate cancer",{"$nulls":3},"GO:0005576///extracellular region","GO:0019903///protein phosphatase binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0051082///unfolded protein binding+++GO:0050750///low-density lipoprotein particle receptor binding","GO:0043066///negative regulation of apoptotic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0001666///response to hypoxia+++GO:0036500///ATF6-mediated unfolded protein response+++GO:0043687///post-translational protein modification+++GO:0031247///actin rod assembly+++GO:0002224///toll-like receptor signaling pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0034976///response to endoplasmic reticulum stress+++GO:0044267///cellular protein metabolic process+++GO:0051208///sequestering of calcium ion+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0006898///receptor-mediated endocytosis+++GO:0015031///protein transport+++GO:0071318///cellular response to ATP","chromosome 12 open reading frame 73","[CL073_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C12orf73; Flags: Precursor;+++[F8VQR3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf73 {ECO:0000313|Ensembl:ENSP00000450253};+++[F8VS87_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf73 {ECO:0000313|Ensembl:ENSP00000447827};+++[F8VXG8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf73 {ECO:0000313|Ensembl:ENSP00000448863};+++[G3V1W1_HUMAN|Unreviewed]SubName: Full=HCG21868, isoform CRA_a {ECO:0000313|EMBL:EAW97725.1};"]
[7288,"'TULP2'",2,12,6,6.66666666666667,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005929///cilium","GO:0035091///phosphatidylinositol binding+++GO:0044877///protein-containing complex binding","GO:0061512///protein localization to cilium+++GO:0007601///visual perception+++GO:0097500///receptor localization to non-motile cilium+++GO:1903546///protein localization to photoreceptor outer segment","tubby like protein 2","[TULP2_HUMAN|Reviewed]RecName: Full=Tubby-related protein 2; AltName: Full=Cancer/testis antigen 65; Short=CT65; AltName: Full=Tubby-like protein 2;+++[E5RH05_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 2 {ECO:0000313|Ensembl:ENSP00000430040}; Flags: Fragment;+++[E5RHR0_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 2 {ECO:0000313|Ensembl:ENSP00000428535}; Flags: Fragment;+++[E5RIF7_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 2 {ECO:0000313|Ensembl:ENSP00000428420}; Flags: Fragment;+++[H0YBB5_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 2 {ECO:0000313|Ensembl:ENSP00000429131}; Flags: Fragment;"]
[7289,"'TULP3'",796,795,752,781,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0097546///ciliary base+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005930///axoneme+++GO:0005929///cilium+++GO:0097731///9+0 non-motile cilium+++GO:0005730///nucleolus+++GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0044877///protein-containing complex binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019899///enzyme binding+++GO:0120160///intraciliary transport particle A binding+++GO:0035091///phosphatidylinositol binding+++GO:0005515///protein binding","GO:0021904///dorsal/ventral neural tube patterning+++GO:0042733///embryonic digit morphogenesis+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0061512///protein localization to cilium+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060173///limb development+++GO:0061548///ganglion development+++GO:0097500///receptor localization to non-motile cilium+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0007420///brain development+++GO:0001841///neural tube formation+++GO:0060348///bone development+++GO:0021914///negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0031076///embryonic camera-type eye development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:1903546///protein localization to photoreceptor outer segment+++GO:0001843///neural tube closure+++GO:0009952///anterior/posterior pattern specification+++GO:0021915///neural tube development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0060434///bronchus morphogenesis+++GO:0021953///central nervous system neuron differentiation+++GO:0007275///multicellular organism development","tubby like protein 3","[TULP3_HUMAN|Reviewed]RecName: Full=Tubby-related protein 3; AltName: Full=Tubby-like protein 3;+++[B7Z1E7_HUMAN|Unreviewed]RecName: Full=Tubby-like protein {ECO:0000256|RuleBase:RU361125};+++[F5GWL5_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000441599};+++[F5H7B9_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000442631}; Flags: Fragment;+++[H0YFU8_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000440364}; Flags: Fragment;+++[H0YG12_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000441319}; Flags: Fragment;"]
[7297,"'TYK2'",1695.62,1767.32,1660,1707.64666666667,"05164///Influenza A+++05145///Toxoplasmosis+++05162///Measles+++05165///Human papillomavirus infection+++04621///NOD-like receptor signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05168///Herpes simplex infection+++04217///Necroptosis+++05169///Epstein-Barr virus infection+++04658///Th1 and Th2 cell differentiation+++04380///Osteoclast differentiation+++04630///Jak-STAT signaling pathway+++05160///Hepatitis C+++04659///Th17 cell differentiation","H00107///Other well-defined immunodeficiency syndromes+++H01968///Hyper-IgE syndrome","M00684///JAK-STAT signaling",null,"GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0005131///growth hormone receptor binding+++GO:0031702///type 1 angiotensin receptor binding+++GO:0005515///protein binding+++GO:0016301///kinase activity","GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0060337///type I interferon signaling pathway+++GO:0016310///phosphorylation+++GO:0038155///interleukin-23-mediated signaling pathway+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0035722///interleukin-12-mediated signaling pathway","tyrosine kinase 2","[TYK2_HUMAN|Reviewed]RecName: Full=Non-receptor tyrosine-protein kinase TYK2; EC=2.7.10.2;+++[A0A024R7E4_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|PIRNR:PIRNR000636, ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|PIRNR:PIRNR000636, ECO:0000256|RuleBase:RU362096};+++[E9PM19_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};+++[E9PPF2_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};+++[E9PQE9_HUMAN|Unreviewed]SubName: Full=Non-receptor tyrosine-protein kinase TYK2 {ECO:0000313|Ensembl:ENSP00000436826}; Flags: Fragment;+++[E9PQL2_HUMAN|Unreviewed]SubName: Full=Non-receptor tyrosine-protein kinase TYK2 {ECO:0000313|Ensembl:ENSP00000436175}; Flags: Fragment;+++[H0YCT7_HUMAN|Unreviewed]SubName: Full=Non-receptor tyrosine-protein kinase TYK2 {ECO:0000313|Ensembl:ENSP00000432320}; Flags: Fragment;+++[H0YE24_HUMAN|Unreviewed]SubName: Full=Non-receptor tyrosine-protein kinase TYK2 {ECO:0000313|Ensembl:ENSP00000434831}; Flags: Fragment;+++[H0YE41_HUMAN|Unreviewed]SubName: Full=Non-receptor tyrosine-protein kinase TYK2 {ECO:0000313|Ensembl:ENSP00000434931}; Flags: Fragment;+++[K7EJR6_HUMAN|Unreviewed]SubName: Full=Non-receptor tyrosine-protein kinase TYK2 {ECO:0000313|Ensembl:ENSP00000465291}; Flags: Fragment;+++[K7EM33_HUMAN|Unreviewed]SubName: Full=Non-receptor tyrosine-protein kinase TYK2 {ECO:0000313|Ensembl:ENSP00000466340}; Flags: Fragment;"]
[729857,"'RGPD2'",1.05,0,0.43,0.493333333333333,"03013///RNA transport","H01363///NARP syndrome+++H01355///Kearns-Sayre syndrome+++H01206///Plasminogen deficiency+++H00223///Inherited thrombophilia+++H01177///Infantile bilateral striatal necrosis (IBSN)+++H00068///Leber hereditary optic atrophy (LHON)+++H01369///ATP synthase deficiency","M00427///Nuclear pore complex",null,"GO:0062023///collagen-containing extracellular matrix+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0031965///nuclear membrane+++GO:0072562///blood microparticle+++GO:0031093///platelet alpha granule lumen+++GO:0031232///extrinsic component of external side of plasma membrane+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005615///extracellular space+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion+++GO:0044218///other organism cell membrane+++GO:0005622///intracellular+++GO:0070062///extracellular exosome","GO:0015078///proton transmembrane transporter activity+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0019900///kinase binding+++GO:0005102///signaling receptor binding+++GO:0050699///WW domain binding+++GO:0008236///serine-type peptidase activity+++GO:1904854///proteasome core complex binding+++GO:0004252///serine-type endopeptidase activity+++GO:1990405///protein antigen binding+++GO:0051087///chaperone binding+++GO:0019904///protein domain specific binding+++GO:0034185///apolipoprotein binding+++GO:0022857///transmembrane transporter activity+++GO:0019899///enzyme binding+++GO:0004175///endopeptidase activity+++GO:0042803///protein homodimerization activity","GO:0055093///response to hyperoxia+++GO:0051702///interaction with symbiont+++GO:0042730///fibrinolysis+++GO:0007568///aging+++GO:0044267///cellular protein metabolic process+++GO:0007596///blood coagulation+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0051919///positive regulation of fibrinolysis+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0042407///cristae formation+++GO:0046907///intracellular transport+++GO:0051918///negative regulation of fibrinolysis+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0008285///negative regulation of cell proliferation+++GO:0006508///proteolysis+++GO:0048771///tissue remodeling+++GO:0052213///interaction with symbiont via secreted substance involved in symbiotic interaction+++GO:0006754///ATP biosynthetic process+++GO:0006979///response to oxidative stress+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:0022617///extracellular matrix disassembly+++GO:0002576///platelet degranulation+++GO:0052182///modification by host of symbiont morphology or physiology via secreted substance","RANBP2-like and GRIP domain containing 2","[RGPD2_HUMAN|Reviewed]RecName: Full=RANBP2-like and GRIP domain-containing protein 2; AltName: Full=Ran-binding protein 2-like 2; Short=RanBP2-like 2; Short=RanBP2L2;+++[A0A1W2PNU4_HUMAN|Unreviewed]SubName: Full=RANBP2-like and GRIP domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000491054};+++[B4DYH0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56975, highly similar to Ran-binding protein 2-like 6 {ECO:0000313|EMBL:BAG63732.1};"]
[730755,"'KRTAP2-3'",50,42.98,50.95,47.9766666666667,{"$nulls":4},"GO:0045095///keratin filament+++GO:0005882///intermediate filament+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0031424///keratinization","keratin associated protein 2-3","[KRA23_HUMAN|Reviewed]RecName: Full=Keratin-associated protein 2-3; AltName: Full=High sulfur keratin-associated protein 2.4; AltName: Full=Keratin-associated protein 2.3;+++[KRA24_HUMAN|Reviewed]RecName: Full=Keratin-associated protein 2-4; AltName: Full=High sulfur keratin-associated protein 2.4; AltName: Full=Keratin-associated protein 2.4;"]
[7327,"'UBE2G2'",831.85,870.04,706.57,802.82,"04141///Protein processing in endoplasmic reticulum+++05012///Parkinson's disease+++04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum","GO:0061631///ubiquitin conjugating enzyme activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0044257///cellular protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol+++GO:0035458///cellular response to interferon-beta+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0030433///ubiquitin-dependent ERAD pathway","ubiquitin conjugating enzyme E2 G2","[UB2G2_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 G2; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme G2; AltName: Full=Ubiquitin carrier protein G2; AltName: Full=Ubiquitin-protein ligase G2;+++[F8WCB9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 G2 {ECO:0000313|Ensembl:ENSP00000418423};+++[F8WDB1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 G2 {ECO:0000313|Ensembl:ENSP00000420671};"]
[7337,"'UBE3A'",1072,978,923,991,"05165///Human papillomavirus infection+++05203///Viral carcinogenesis+++04120///Ubiquitin mediated proteolysis","H01732///Angelman syndrome (AS)",null,null,"GO:0005634///nucleus+++GO:0000502///proteasome complex+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016874///ligase activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity","GO:0042752///regulation of circadian rhythm+++GO:0051865///protein autoubiquitination+++GO:0000209///protein polyubiquitination+++GO:0006508///proteolysis+++GO:0007420///brain development+++GO:0050847///progesterone receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0016032///viral process+++GO:0016567///protein ubiquitination+++GO:0032570///response to progesterone+++GO:0070936///protein K48-linked ubiquitination+++GO:2000058///regulation of ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process","ubiquitin protein ligase E3A","[UBE3A_HUMAN|Reviewed]RecName: Full=Ubiquitin-protein ligase E3A; EC=2.3.2.26 {ECO:0000269|PubMed:24273172}; AltName: Full=E6AP ubiquitin-protein ligase {ECO:0000303|PubMed:17108031}; AltName: Full=HECT-type ubiquitin transferase E3A; AltName: Full=Human papillomavirus E6-associated protein {ECO:0000303|PubMed:8380895}; AltName: Full=Oncogenic protein-associated protein E6-AP {ECO:0000303|PubMed:8380895}; AltName: Full=Renal carcinoma antigen NY-REN-54;+++[A0A0D9SEJ2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000485732}; Flags: Fragment;+++[A0A0D9SES7_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000485958}; Flags: Fragment;+++[A0A0D9SF91_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486388}; Flags: Fragment;+++[A0A0D9SFH3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486601}; Flags: Fragment;+++[A0A0D9SFU3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486900}; Flags: Fragment;+++[A0A0D9SG54_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487148}; Flags: Fragment;+++[A0A0D9SG63_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487178}; Flags: Fragment;+++[A0A0D9SG77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487217};+++[A0A0D9SGI3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487534}; Flags: Fragment;+++[A0A0D9SGJ0_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487550}; Flags: Fragment;+++[A0A0G2JQQ5_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486066}; Flags: Fragment;+++[A0A1B0GTB3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000489625};+++[A0A1B0GVL3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000490563};+++[Q5W7F7_HUMAN|Unreviewed]SubName: Full=Ubiquitin ligase E3A isoform 1 {ECO:0000313|EMBL:BAD69554.1};+++[Q96GR7_HUMAN|Unreviewed]SubName: Full=UBE3A protein {ECO:0000313|EMBL:AAH09271.1};+++[Q9BUI6_HUMAN|Unreviewed]SubName: Full=Ubiquitin protein ligase E3A {ECO:0000313|EMBL:AAH02582.2};+++[Q9H2G0_HUMAN|Unreviewed]SubName: Full=CTCL tumor antigen se37-2 {ECO:0000313|EMBL:AAG34910.1}; SubName: Full=Ubiquitin protein ligase E3A (Human papilloma virus E6-associated protein, Angelman syndrome), isoform CRA_b {ECO:0000313|EMBL:EAW57643.1}; SubName: Full=cDNA FLJ77551, highly similar to Homo sapiens ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (UBE3A), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84094.1};+++[Q9UBN9_HUMAN|Unreviewed]SubName: Full=E6-AP ubiquitin-protein ligase {ECO:0000313|EMBL:AAC39580.1}; Flags: Fragment;+++[S4R306_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000473822}; Flags: Fragment;"]
[7350,"'UCP1'",3,5,4,4,"03320///PPAR signaling pathway+++04371///Apelin signaling pathway+++05016///Huntington's disease+++04714///Thermogenesis","H02106///Genetic obesity",null,null,"GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005740///mitochondrial envelope","GO:1901612///cardiolipin binding+++GO:0017077///oxidative phosphorylation uncoupler activity+++GO:0036041///long-chain fatty acid binding+++GO:0032555///purine ribonucleotide binding+++GO:0022857///transmembrane transporter activity","GO:0006839///mitochondrial transport+++GO:0071398///cellular response to fatty acid+++GO:0009266///response to temperature stimulus+++GO:1903426///regulation of reactive oxygen species biosynthetic process+++GO:0002024///diet induced thermogenesis+++GO:1990845///adaptive thermogenesis+++GO:0006811///ion transport+++GO:0034614///cellular response to reactive oxygen species+++GO:0031667///response to nutrient levels+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:1990542///mitochondrial transmembrane transport+++GO:0032870///cellular response to hormone stimulus+++GO:1902600///proton transmembrane transport+++GO:0050873///brown fat cell differentiation+++GO:0009409///response to cold+++GO:0120162///positive regulation of cold-induced thermogenesis","uncoupling protein 1","[UCP1_HUMAN|Reviewed]RecName: Full=Mitochondrial brown fat uncoupling protein 1 {ECO:0000305}; Short=UCP 1 {ECO:0000305}; AltName: Full=Solute carrier family 25 member 7 {ECO:0000303|PubMed:23266187}; AltName: Full=Thermogenin {ECO:0000250|UniProtKB:P04575};+++[Q4KMT7_HUMAN|Unreviewed]SubName: Full=Uncoupling protein 1 (Mitochondrial, proton carrier) {ECO:0000313|EMBL:AAH98352.1};"]
[7388,"'UQCRH'",631,696.93,677,668.31,"01100///Metabolic pathways+++05010///Alzheimer's disease+++05016///Huntington's disease+++05012///Parkinson's disease+++04714///Thermogenesis+++00190///Oxidative phosphorylation+++04260///Cardiac muscle contraction+++04932///Non-alcoholic fatty liver disease (NAFLD)",null,"M00152///Cytochrome bc1 complex",null,"GO:0070469///respiratory chain+++GO:0005746///mitochondrial respiratory chain+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0008121///ubiquinol-cytochrome-c reductase activity+++GO:0005515///protein binding","GO:0009060///aerobic respiration+++GO:0006119///oxidative phosphorylation+++GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0055114///oxidation-reduction process","ubiquinol-cytochrome c reductase hinge protein","[QCR6_HUMAN|Reviewed]RecName: Full=Cytochrome b-c1 complex subunit 6, mitochondrial; AltName: Full=Complex III subunit 6; AltName: Full=Complex III subunit VIII; AltName: Full=Cytochrome c1 non-heme 11 kDa protein; AltName: Full=Mitochondrial hinge protein; AltName: Full=Ubiquinol-cytochrome c reductase complex 11 kDa protein; Flags: Precursor;+++[A0A087WTF2_HUMAN|Unreviewed]SubName: Full=Cytochrome b-c1 complex subunit 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000477826};+++[A0A087X2B9_HUMAN|Unreviewed]SubName: Full=Cytochrome b-c1 complex subunit 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000484857};+++[Q567R0_HUMAN|Unreviewed]SubName: Full=UQCRH protein {ECO:0000313|EMBL:AAH93060.1}; SubName: Full=Ubiquinol-cytochrome c reductase hinge protein, isoform CRA_c {ECO:0000313|EMBL:EAX06925.1};"]
[740,"'MRPL49'",817,800,765,794,"04141///Protein processing in endoplasmic reticulum+++04120///Ubiquitin mediated proteolysis",null,"M00403///HRD1/SEL1 ERAD complex",null,"GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005761///mitochondrial ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding","GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination+++GO:0006412///translation","mitochondrial ribosomal protein L49","[RM49_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L49, mitochondrial; Short=L49mt; Short=MRP-L49; AltName: Full=Mitochondrial large ribosomal subunit protein mL49 {ECO:0000303|PubMed:25278503}; AltName: Full=Neighbor of FAU; Short=NOF; AltName: Full=Protein NOF1;+++[A0A024R578_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein L49, isoform CRA_b {ECO:0000313|EMBL:EAW74356.1};+++[E9PI78_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L49, mitochondrial {ECO:0000313|Ensembl:ENSP00000436740};+++[E9PNF1_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L49, mitochondrial {ECO:0000313|Ensembl:ENSP00000437177};+++[E9PRD2_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L49, mitochondrial {ECO:0000313|Ensembl:ENSP00000434222};+++[H0YDP7_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L49, mitochondrial {ECO:0000313|Ensembl:ENSP00000434052}; Flags: Fragment;"]
[7419,"'VDAC3'",787,735,681,734.333333333333,"04022///cGMP-PKG signaling pathway+++04217///Necroptosis+++05166///HTLV-I infection+++04979///Cholesterol metabolism+++05012///Parkinson's disease+++04216///Ferroptosis+++04020///Calcium signaling pathway+++05203///Viral carcinogenesis+++04621///NOD-like receptor signaling pathway+++05161///Hepatitis B+++05016///Huntington's disease+++04218///Cellular senescence",{"$nulls":3},"GO:0046930///pore complex+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005741///mitochondrial outer membrane+++GO:0070062///extracellular exosome","GO:0008308///voltage-gated anion channel activity+++GO:0015288///porin activity+++GO:0000166///nucleotide binding","GO:0007270///neuron-neuron synaptic transmission+++GO:1902017///regulation of cilium assembly+++GO:0007612///learning+++GO:0001662///behavioral fear response+++GO:0015853///adenine transport","voltage dependent anion channel 3","[VDAC3_HUMAN|Reviewed]RecName: Full=Voltage-dependent anion-selective channel protein 3; Short=VDAC-3; Short=hVDAC3; AltName: Full=Outer mitochondrial membrane protein porin 3;"]
[746,"'TMEM258'",190,155,180,175,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0034998///oligosaccharyltransferase I complex+++GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008233///peptidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding","GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation","transmembrane protein 258","[TM258_HUMAN|Reviewed]RecName: Full=Transmembrane protein 258;+++[F5GWH5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 258 {ECO:0000313|Ensembl:ENSP00000441836};+++[F5H7Z5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 258 {ECO:0000313|Ensembl:ENSP00000443836};"]
[7466,"'WFS1'",4766,4464,4055,4428.33333333333,"04141///Protein processing in endoplasmic reticulum","H00854///Wolfram syndrome (WFS)+++H01202///Cataract+++H01705///Bilateral sudden sensorineural hearing loss+++H00409///Type II diabetes mellitus+++H00604///Deafness, autosomal dominant",null,null,"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0000502///proteasome complex+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0030425///dendrite","GO:0031625///ubiquitin protein ligase binding+++GO:0033613///activating transcription factor binding+++GO:0005516///calmodulin binding+++GO:0048306///calcium-dependent protein binding+++GO:0005515///protein binding+++GO:0051117///ATPase binding","GO:0001822///kidney development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0043687///post-translational protein modification+++GO:0042048///olfactory behavior+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0051928///positive regulation of calcium ion transport+++GO:0031016///pancreas development+++GO:0022417///protein maturation by protein folding+++GO:0044267///cellular protein metabolic process+++GO:0055074///calcium ion homeostasis+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0006983///ER overload response+++GO:0050821///protein stabilization+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0045927///positive regulation of growth+++GO:0007605///sensory perception of sound+++GO:0050877///nervous system process+++GO:0003091///renal water homeostasis+++GO:0007601///visual perception+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0051247///positive regulation of protein metabolic process+++GO:0042593///glucose homeostasis+++GO:0031398///positive regulation of protein ubiquitination+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:1903892///negative regulation of ATF6-mediated unfolded protein response+++GO:0043069///negative regulation of programmed cell death+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:2000675///negative regulation of type B pancreatic cell apoptotic process","wolframin ER transmembrane glycoprotein","[WFS1_HUMAN|Reviewed]RecName: Full=Wolframin;+++[A0A0S2Z4V4_HUMAN|Unreviewed]SubName: Full=Wolfram syndrome 1 isoform 2 {ECO:0000313|EMBL:ALQ33854.1};+++[A0A0S2Z4V6_HUMAN|Unreviewed]SubName: Full=Wolfram syndrome 1 isoform 1 {ECO:0000313|EMBL:ALQ33853.1}; Flags: Fragment;+++[H0Y9G5_HUMAN|Unreviewed]SubName: Full=Wolframin {ECO:0000313|Ensembl:ENSP00000424103}; Flags: Fragment;"]
[7516,"'XRCC2'",12.9,11,13,12.3,"03440///Homologous recombination","H00238///Fanconi anemia",null,null,"GO:0005856///cytoskeleton+++GO:0033063///Rad51B-Rad51C-Rad51D-XRCC2 complex+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005657///replication fork+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005815///microtubule organizing center+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000400///four-way junction DNA binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0005524///ATP binding+++GO:0003677///DNA binding","GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:0001756///somitogenesis+++GO:0000724///double-strand break repair via homologous recombination+++GO:0042148///strand invasion+++GO:2000269///regulation of fibroblast apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050769///positive regulation of neurogenesis+++GO:0000278///mitotic cell cycle+++GO:0051321///meiotic cell cycle+++GO:0007098///centrosome cycle+++GO:0010332///response to gamma radiation+++GO:0001701///in utero embryonic development+++GO:0010165///response to X-ray+++GO:0022008///neurogenesis+++GO:0035264///multicellular organism growth","X-ray repair cross complementing 2","[XRCC2_HUMAN|Reviewed]RecName: Full=DNA repair protein XRCC2; AltName: Full=X-ray repair cross-complementing protein 2;"]
[7520,"'XRCC5'",3831,3955,3762,3849.33333333333,"03450///Non-homologous end-joining",null,"M00297///DNA-PK complex",null,"GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0000783///nuclear telomere cap complex+++GO:0070419///nonhomologous end joining complex+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0034774///secretory granule lumen+++GO:0005634///nucleus+++GO:0032993///protein-DNA complex+++GO:0000784///nuclear chromosome, telomeric region+++GO:0090734///site of DNA damage+++GO:0043564///Ku70:Ku80 complex+++GO:0005694///chromosome+++GO:0005576///extracellular region+++GO:0005575///cellular_component+++GO:0005730///nucleolus","GO:0003674///molecular_function+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0008047///enzyme activator activity+++GO:0003690///double-stranded DNA binding+++GO:0016817///hydrolase activity, acting on acid anhydrides+++GO:0031625///ubiquitin protein ligase binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0045027///DNA end binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0003723///RNA binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0003684///damaged DNA binding+++GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0044877///protein-containing complex binding+++GO:0008022///protein C-terminus binding+++GO:0042162///telomeric DNA binding+++GO:0005524///ATP binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006310///DNA recombination+++GO:1904430///negative regulation of t-circle formation+++GO:0032508///DNA duplex unwinding+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0006302///double-strand break repair+++GO:0075713///establishment of integrated proviral latency+++GO:0032204///regulation of telomere maintenance+++GO:0002376///immune system process+++GO:0006282///regulation of DNA repair+++GO:0032481///positive regulation of type I interferon production+++GO:0071481///cellular response to X-ray+++GO:0043085///positive regulation of catalytic activity+++GO:0050769///positive regulation of neurogenesis+++GO:0071475///cellular hyperosmotic salinity response+++GO:0051973///positive regulation of telomerase activity+++GO:0045087///innate immune response+++GO:0071398///cellular response to fatty acid+++GO:0008283///cell proliferation+++GO:0045860///positive regulation of protein kinase activity+++GO:0042493///response to drug+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0070198///protein localization to chromosome, telomeric region+++GO:0007420///brain development+++GO:0043312///neutrophil degranulation+++GO:0060218///hematopoietic stem cell differentiation+++GO:0000723///telomere maintenance+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0006281///DNA repair+++GO:0002218///activation of innate immune response+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0071480///cellular response to gamma radiation","X-ray repair cross complementing 5","[XRCC5_HUMAN|Reviewed]RecName: Full=X-ray repair cross-complementing protein 5; EC=3.6.4.-; AltName: Full=86 kDa subunit of Ku antigen; AltName: Full=ATP-dependent DNA helicase 2 subunit 2; AltName: Full=ATP-dependent DNA helicase II 80 kDa subunit; AltName: Full=CTC box-binding factor 85 kDa subunit; Short=CTC85; Short=CTCBF; AltName: Full=DNA repair protein XRCC5; AltName: Full=Ku80; AltName: Full=Ku86; AltName: Full=Lupus Ku autoantigen protein p86; AltName: Full=Nuclear factor IV; AltName: Full=Thyroid-lupus autoantigen; Short=TLAA; AltName: Full=X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining);+++[C9JZ81_HUMAN|Unreviewed]SubName: Full=X-ray repair cross-complementing protein 5 {ECO:0000313|Ensembl:ENSP00000401318}; Flags: Fragment;+++[H7C0H9_HUMAN|Unreviewed]SubName: Full=X-ray repair cross-complementing protein 5 {ECO:0000313|Ensembl:ENSP00000395108}; Flags: Fragment;+++[O43594_HUMAN|Unreviewed]SubName: Full=Ku86 autoantigen related protein 1 {ECO:0000313|EMBL:AAC52087.1}; Flags: Fragment;+++[Q53T09_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein XRCC5 {ECO:0000313|EMBL:AAY24231.1}; Flags: Fragment;+++[Q53TC2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein XRCC5 {ECO:0000313|EMBL:AAY14659.1}; Flags: Fragment;"]
[7542,"'ZFPL1'",878,945,837,886.666666666667,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0016192///vesicle-mediated transport","zinc finger protein like 1","[ZFPL1_HUMAN|Reviewed]RecName: Full=Zinc finger protein-like 1; AltName: Full=Zinc finger protein MCG4;+++[A0A024R576_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW74346.1};+++[A0A0G2JKQ6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000434780}; Flags: Fragment;+++[E9PJ47_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000435677};+++[E9PJX1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000433673};+++[E9PMQ3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000415088};+++[E9PNY1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000437090}; Flags: Fragment;+++[E9PQ47_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000434454}; Flags: Fragment;+++[E9PQA5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000432529}; Flags: Fragment;+++[H0YCU8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein-like 1 {ECO:0000313|Ensembl:ENSP00000432377}; Flags: Fragment;"]
[7559,"'ZNF12'",246,290,242,259.333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger protein 12","[ZNF12_HUMAN|Reviewed]RecName: Full=Zinc finger protein 12; AltName: Full=Gonadotropin-inducible ovary transcription repressor 3; Short=GIOT-3; AltName: Full=Zinc finger protein 325; AltName: Full=Zinc finger protein KOX3;+++[H9KV98_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 12 {ECO:0000313|Ensembl:ENSP00000378375}; Flags: Fragment;+++[Q6RFS4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 11 {ECO:0000313|EMBL:AAS55104.1}; Flags: Fragment;"]
[7581,"'ZNF33A'",535,556.07,514.03,535.033333333333,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 33A","[ZN33A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 33A; AltName: Full=Zinc finger and ZAK-associated protein with KRAB domain; Short=ZZaPK; AltName: Full=Zinc finger protein 11A; AltName: Full=Zinc finger protein KOX31;+++[A0A0A0MR11_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 33A {ECO:0000313|Ensembl:ENSP00000304268};+++[A0A0A0MRS1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 33A {ECO:0000313|Ensembl:ENSP00000363747};+++[A0AUX1_HUMAN|Unreviewed]SubName: Full=ZNF33A protein {ECO:0000313|EMBL:AAI26120.1};+++[Q05D89_HUMAN|Unreviewed]SubName: Full=ZNF33A protein {ECO:0000313|EMBL:AAH17760.1}; Flags: Fragment;+++[Q8N6F5_HUMAN|Unreviewed]SubName: Full=ZNF33A protein {ECO:0000313|EMBL:AAH30511.1}; Flags: Fragment;+++[Q9H5I4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 33A, isoform CRA_c {ECO:0000313|EMBL:EAW85890.1}; SubName: Full=cDNA: FLJ23404 fis, clone HEP18862 {ECO:0000313|EMBL:BAB15642.1};"]
[762,"'CA4'",32,66,51,49.6666666666667,"04964///Proximal tubule bicarbonate reclamation+++00910///Nitrogen metabolism","H00527///Retinitis pigmentosa (RP)",null,"R10092///carbonate hydro-lyase (carbon-dioxide-forming)   HCO3- + H+ <=> CO2 + H2O","GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005802///trans-Golgi network+++GO:0031526///brush border membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0030667///secretory granule membrane+++GO:0031225///anchored component of membrane+++GO:0009986///cell surface+++GO:0005791///rough endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0030658///transport vesicle membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0046658///anchored component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0016323///basolateral plasma membrane","GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004089///carbonate dehydratase activity+++GO:0016829///lyase activity","GO:0015701///bicarbonate transport","carbonic anhydrase 4","[CAH4_HUMAN|Reviewed]RecName: Full=Carbonic anhydrase 4; EC=4.2.1.1; AltName: Full=Carbonate dehydratase IV; AltName: Full=Carbonic anhydrase IV; Short=CA-IV; Flags: Precursor;+++[K7EIH9_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase 4 {ECO:0000313|Ensembl:ENSP00000464757}; Flags: Fragment;+++[K7EKY5_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase 4 {ECO:0000313|Ensembl:ENSP00000465837}; Flags: Fragment;+++[K7ENI8_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase 4 {ECO:0000313|Ensembl:ENSP00000466964}; Flags: Fragment;"]
[7673,"'ZNF222'",39,38,30,35.6666666666667,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 222","[ZN222_HUMAN|Reviewed]RecName: Full=Zinc finger protein 222;+++[K7EN43_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 222 {ECO:0000313|Ensembl:ENSP00000466778};"]
[770,"'CA11'",1200,1364,1080,1214.66666666667,{"$nulls":4},"GO:0016323///basolateral plasma membrane+++GO:0005576///extracellular region","GO:0008270///zinc ion binding",null,"carbonic anhydrase 11","[CAH11_HUMAN|Reviewed]RecName: Full=Carbonic anhydrase-related protein 11; AltName: Full=CA-RP XI; Short=CA-XI; Short=CARP XI; AltName: Full=Carbonic anhydrase-related protein 2; Short=CA-RP II; Short=CARP-2; Flags: Precursor;"]
[7726,"'TRIM26'",1083,1096,1017,1065.33333333333,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0005575///cellular_component+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003677///DNA binding","GO:0044267///cellular protein metabolic process+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0043687///post-translational protein modification+++GO:0045087///innate immune response+++GO:0060395///SMAD protein signal transduction+++GO:0001542///ovulation from ovarian follicle+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0019953///sexual reproduction+++GO:0046597///negative regulation of viral entry into host cell+++GO:1902187///negative regulation of viral release from host cell+++GO:0002376///immune system process+++GO:0042448///progesterone metabolic process","tripartite motif containing 26","[TRI26_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 26; EC=2.3.2.27 {ECO:0000269|PubMed:26611359}; AltName: Full=Acid finger protein; Short=AFP; AltName: Full=RING finger protein 95; AltName: Full=Zinc finger protein 173;+++[A0A024RCP3_HUMAN|Unreviewed]SubName: Full=TRIM26 {ECO:0000313|EMBL:AQY77163.1}; SubName: Full=Tripartite motif-containing 26, isoform CRA_a {ECO:0000313|EMBL:EAX03276.1};+++[A0A0G2JIW2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 26 {ECO:0000313|Ensembl:ENSP00000402684}; Flags: Fragment;+++[A2AE48_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 26 {ECO:0000313|Ensembl:ENSP00000413673}; Flags: Fragment;+++[A2AE50_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 26 {ECO:0000313|Ensembl:ENSP00000400920}; Flags: Fragment;+++[J3KMX3_HUMAN|Unreviewed]SubName: Full=Alpha-fetoprotein {ECO:0000313|Ensembl:ENSP00000226359};+++[Q5SPU2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 26 {ECO:0000313|Ensembl:ENSP00000387530}; Flags: Fragment;"]
[7748,"'ZNF195'",244,272,236,250.666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 195","[ZN195_HUMAN|Reviewed]RecName: Full=Zinc finger protein 195;+++[A0A087WT67_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000477630};+++[C9JG37_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000390663}; Flags: Fragment;+++[E9PIN4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000435741};+++[E9PIT0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000433911}; Flags: Fragment;+++[E9PIY8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000431937}; Flags: Fragment;+++[E9PLF5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000435153}; Flags: Fragment;+++[E9PLW9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000435093};+++[E9PMX5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000437265}; Flags: Fragment;+++[E9PNM0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000434715}; Flags: Fragment;+++[E9PPF8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000432720};+++[E9PSE6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000434006}; Flags: Fragment;+++[H0YDV1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 195 {ECO:0000313|Ensembl:ENSP00000434361}; Flags: Fragment;"]
[777,"'CACNA1E'",1,0,0,0.333333333333333,"04020///Calcium signaling pathway+++04930///Type II diabetes mellitus+++04010///MAPK signaling pathway","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005244///voltage-gated ion channel activity+++GO:0005262///calcium channel activity+++GO:0046872///metal ion binding+++GO:0005216///ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005509///calcium ion binding","GO:0070509///calcium ion import+++GO:0055085///transmembrane transport+++GO:0006816///calcium ion transport+++GO:0007268///chemical synaptic transmission+++GO:0034765///regulation of ion transmembrane transport+++GO:0051899///membrane depolarization+++GO:0070588///calcium ion transmembrane transport+++GO:0006811///ion transport+++GO:0050796///regulation of insulin secretion","calcium voltage-gated channel subunit alpha1 E","[CAC1E_HUMAN|Reviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha-1E; AltName: Full=Brain calcium channel II; Short=BII; AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 6; AltName: Full=Voltage-gated calcium channel subunit alpha Cav2.3;+++[A0A024R920_HUMAN|Unreviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808};+++[A0A2R8Y7W1_HUMAN|Unreviewed]SubName: Full=Voltage-dependent R-type calcium channel subunit alpha-1E {ECO:0000313|Ensembl:ENSP00000496576}; Flags: Fragment;+++[E9PIE8_HUMAN|Unreviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808}; Flags: Fragment;+++[F8W9Z1_HUMAN|Unreviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808};+++[J3KP11_HUMAN|Unreviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808};+++[Q59FG1_HUMAN|Unreviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808}; Flags: Fragment;+++[Q9NY05_HUMAN|Unreviewed]SubName: Full=Voltage-dependent calcium channel alpha 1E subunit {ECO:0000313|EMBL:CAB81554.1}; Flags: Fragment;+++[Q9NYZ5_HUMAN|Unreviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808}; Flags: Fragment;+++[Q9NYZ6_HUMAN|Unreviewed]RecName: Full=Voltage-dependent R-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808}; Flags: Fragment;+++[Q9UN68_HUMAN|Unreviewed]SubName: Full=Voltage-gated calcium channel alpha 1E subunit {ECO:0000313|EMBL:AAD38389.1}; Flags: Fragment;"]
[7789,"'ZXDA'",90.82,89.49,75.27,85.1933333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger X-linked duplicated A","[ZXDA_HUMAN|Reviewed]RecName: Full=Zinc finger X-linked protein ZXDA;"]
[782,"'CACNB1'",207,191,180,192.666666666667,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04010///MAPK signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04261///Adrenergic signaling in cardiomyocytes+++05410///Hypertrophic cardiomyopathy (HCM)+++04921///Oxytocin signaling pathway+++04260///Cardiac muscle contraction",{"$nulls":3},"GO:0016020///membrane+++GO:0005891///voltage-gated calcium channel complex+++GO:0042383///sarcolemma+++GO:0005886///plasma membrane","GO:0008331///high voltage-gated calcium channel activity+++GO:0005515///protein binding+++GO:0005245///voltage-gated calcium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005262///calcium channel activity","GO:1904646///cellular response to amyloid-beta+++GO:0070588///calcium ion transmembrane transport+++GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:0006816///calcium ion transport+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:0034765///regulation of ion transmembrane transport+++GO:0007528///neuromuscular junction development","calcium voltage-gated channel auxiliary subunit beta 1","[CACB1_HUMAN|Reviewed]RecName: Full=Voltage-dependent L-type calcium channel subunit beta-1; Short=CAB1; AltName: Full=Calcium channel voltage-dependent subunit beta 1;+++[Q6TME4_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-1 {ECO:0000313|Ensembl:ENSP00000477612}; SubName: Full=Voltage-gated calcium channel beta 1 subunit splice variant CavB1d {ECO:0000313|EMBL:AAQ97605.1};"]
[7871,"'SLMAP'",908,793,683,794.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042383///sarcolemma+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0017048///Rho GTPase binding+++GO:0005515///protein binding","GO:1905150///regulation of voltage-gated sodium channel activity+++GO:0072659///protein localization to plasma membrane+++GO:1902305///regulation of sodium ion transmembrane transport+++GO:1900825///regulation of membrane depolarization during cardiac muscle cell action potential+++GO:0006936///muscle contraction","sarcolemma associated protein","[SLMAP_HUMAN|Reviewed]RecName: Full=Sarcolemmal membrane-associated protein; Short=Sarcolemmal-associated protein;+++[B7Z6C7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54546, highly similar to Homo sapiens sarcolemma associated protein (SLMAP), mRNA {ECO:0000313|EMBL:BAH13213.1};+++[B7Z863_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000418218}; SubName: Full=cDNA FLJ54742, highly similar to Mus musculus sarcolemma associated protein (Slmap), mRNA {ECO:0000313|EMBL:BAH13849.1};+++[B7Z964_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000419543}; SubName: Full=cDNA FLJ60222, highly similar to Homo sapiens sarcolemma associated protein (SLMAP), mRNA {ECO:0000313|EMBL:BAH14200.1}; SubName: Full=cDNA, FLJ79335, highly similar to Homo sapiens sarcolemma associated protein (SLMAP), mRNA {ECO:0000313|EMBL:BAH14807.1};+++[C9JA20_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000417541}; Flags: Fragment;+++[C9JCH4_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000420697}; Flags: Fragment;+++[H7BZK0_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000389978}; Flags: Fragment;+++[H7BZW9_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000391886}; Flags: Fragment;+++[H7C3M8_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000412829}; Flags: Fragment;+++[H7C5G9_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000419849}; Flags: Fragment;+++[H7C5S2_HUMAN|Unreviewed]SubName: Full=Sarcolemmal membrane-associated protein {ECO:0000313|Ensembl:ENSP00000420703}; Flags: Fragment;"]
[78992,"'YIPF2'",1231,1294,1295,1273.33333333333,"01522///Endocrine resistance",null,null,"R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming) S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming) 2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine","GO:0005802///trans-Golgi network+++GO:0005797///Golgi medial cisterna+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0031902///late endosome membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0000138///Golgi trans cisterna+++GO:0030133///transport vesicle","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding","GO:0016192///vesicle-mediated transport","Yip1 domain family member 2","[YIPF2_HUMAN|Reviewed]RecName: Full=Protein YIPF2; AltName: Full=YIP1 family member 2;+++[A0A024R7E1_HUMAN|Unreviewed]RecName: Full=Protein YIPF {ECO:0000256|RuleBase:RU361264};+++[K7EIP7_HUMAN|Unreviewed]RecName: Full=Protein YIPF {ECO:0000256|RuleBase:RU361264}; Flags: Fragment;+++[K7EJN9_HUMAN|Unreviewed]SubName: Full=Protein YIPF2 {ECO:0000313|Ensembl:ENSP00000465257}; Flags: Fragment;+++[K7EL70_HUMAN|Unreviewed]SubName: Full=Protein YIPF2 {ECO:0000313|Ensembl:ENSP00000465943}; Flags: Fragment;+++[K7EM92_HUMAN|Unreviewed]SubName: Full=Protein YIPF2 {ECO:0000313|Ensembl:ENSP00000466408}; Flags: Fragment;+++[K7ENM8_HUMAN|Unreviewed]SubName: Full=Protein YIPF2 {ECO:0000313|Ensembl:ENSP00000467019};+++[K7ENZ5_HUMAN|Unreviewed]SubName: Full=Protein YIPF2 {ECO:0000313|Ensembl:ENSP00000467156}; Flags: Fragment;+++[K7EQH3_HUMAN|Unreviewed]RecName: Full=Protein YIPF {ECO:0000256|RuleBase:RU361264}; Flags: Fragment;+++[K7ERW0_HUMAN|Unreviewed]RecName: Full=Protein YIPF {ECO:0000256|RuleBase:RU361264}; Flags: Fragment;"]
[79019,"'CENPM'",1,2,4,2.33333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0005694///chromosome",null,"GO:0034080///CENP-A containing nucleosome assembly","centromere protein M","[CENPM_HUMAN|Reviewed]RecName: Full=Centromere protein M; Short=CENP-M; AltName: Full=Interphase centromere complex protein 39; AltName: Full=Proliferation-associated nuclear element protein 1;+++[A0A024R1Q3_HUMAN|Unreviewed]SubName: Full=Chromosome 22 open reading frame 18, isoform CRA_a {ECO:0000313|EMBL:EAW60476.1};+++[B1AHQ6_HUMAN|Unreviewed]SubName: Full=Centromere protein M {ECO:0000313|Ensembl:ENSP00000384731};+++[B1AHQ7_HUMAN|Unreviewed]SubName: Full=Centromere protein M {ECO:0000313|Ensembl:ENSP00000384814};+++[B1AHQ8_HUMAN|Unreviewed]SubName: Full=Centromere protein M {ECO:0000313|Ensembl:ENSP00000384132};"]
[79034,"'C7orf26'",472,499,402,457.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"chromosome 7 open reading frame 26","[CG026_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C7orf26;+++[H7BZK9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C7orf26 {ECO:0000313|Ensembl:ENSP00000390166}; Flags: Fragment;+++[H7C0Q5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C7orf26 {ECO:0000313|Ensembl:ENSP00000396194}; Flags: Fragment;"]
[79058,"'ASPSCR1'",506,572,524,534,"05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0012506///vesicle membrane+++GO:0019898///extrinsic component of membrane+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0012505///endomembrane system+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0046324///regulation of glucose import+++GO:0042593///glucose homeostasis+++GO:0031401///positive regulation of protein modification process","ASPSCR1, UBX domain containing tether for SLC2A4","[ASPC1_HUMAN|Reviewed]RecName: Full=Tether containing UBX domain for GLUT4; AltName: Full=Alveolar soft part sarcoma chromosomal region candidate gene 1 protein; AltName: Full=Alveolar soft part sarcoma locus; AltName: Full=Renal papillary cell carcinoma protein 17; AltName: Full=UBX domain-containing protein 9;+++[C9JAL9_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000344020};+++[J3KRF7_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000461980}; Flags: Fragment;+++[J3KRG1_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000461984}; Flags: Fragment;+++[J3KRY8_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000462218}; Flags: Fragment;+++[J3QL04_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000463316}; Flags: Fragment;+++[J3QR12_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000463992};+++[J3QR50_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000464044};+++[J3QRW3_HUMAN|Unreviewed]SubName: Full=Tether-containing UBX domain for GLUT4 {ECO:0000313|Ensembl:ENSP00000464408};"]
[79072,"'FASTKD3'",47,63,32,47.3333333333333,null,"H00183///Homocystinuria+++H00262///Spina bifida+++H01552///Down syndrome",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0004672///protein kinase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045333///cellular respiration+++GO:0044528///regulation of mitochondrial mRNA stability+++GO:0070131///positive regulation of mitochondrial translation+++GO:0006468///protein phosphorylation+++GO:0033617///mitochondrial respiratory chain complex IV assembly","FAST kinase domains 3","[FAKD3_HUMAN|Reviewed]RecName: Full=FAST kinase domain-containing protein 3, mitochondrial; Flags: Precursor;+++[D6RAR6_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000421798};+++[D6RB04_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000424568};+++[D6RC07_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000422443}; Flags: Fragment;+++[D6RHY4_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000426008}; Flags: Fragment;"]
[79109,"'MAPKAP1'",1996,1909,1824,1909.66666666667,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0031932///TORC2 complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0019901///protein kinase binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0016301///kinase activity+++GO:0017016///Ras GTPase binding+++GO:0070300///phosphatidic acid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding","GO:0032148///activation of protein kinase B activity+++GO:0016310///phosphorylation+++GO:1900407///regulation of cellular response to oxidative stress+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0038203///TORC2 signaling+++GO:0021762///substantia nigra development+++GO:0033138///positive regulation of peptidyl-serine phosphorylation","mitogen-activated protein kinase associated protein 1","[SIN1_HUMAN|Reviewed]RecName: Full=Target of rapamycin complex 2 subunit MAPKAP1; Short=TORC2 subunit MAPKAP1; AltName: Full=Mitogen-activated protein kinase 2-associated protein 1; AltName: Full=Stress-activated map kinase-interacting protein 1; Short=SAPK-interacting protein 1; Short=mSIN1;+++[A0A024R863_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase associated protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW87633.1};+++[B1AMA5_HUMAN|Unreviewed]SubName: Full=Target of rapamycin complex 2 subunit MAPKAP1 {ECO:0000313|Ensembl:ENSP00000400182}; Flags: Fragment;+++[B1AMA6_HUMAN|Unreviewed]SubName: Full=Target of rapamycin complex 2 subunit MAPKAP1 {ECO:0000313|Ensembl:ENSP00000408359}; Flags: Fragment;+++[B1AMB1_HUMAN|Unreviewed]SubName: Full=Target of rapamycin complex 2 subunit MAPKAP1 {ECO:0000313|Ensembl:ENSP00000390024}; Flags: Fragment;+++[B1AMB2_HUMAN|Unreviewed]SubName: Full=Target of rapamycin complex 2 subunit MAPKAP1 {ECO:0000313|Ensembl:ENSP00000362595}; Flags: Fragment;+++[E9PGB8_HUMAN|Unreviewed]SubName: Full=Target of rapamycin complex 2 subunit MAPKAP1 {ECO:0000313|Ensembl:ENSP00000418607};+++[H0Y7F8_HUMAN|Unreviewed]SubName: Full=Target of rapamycin complex 2 subunit MAPKAP1 {ECO:0000313|Ensembl:ENSP00000412485}; Flags: Fragment;+++[H0Y866_HUMAN|Unreviewed]SubName: Full=Target of rapamycin complex 2 subunit MAPKAP1 {ECO:0000313|Ensembl:ENSP00000417766}; Flags: Fragment;+++[L8EC63_HUMAN|Unreviewed]SubName: Full=Alternative protein MAPKAP1 {ECO:0000313|EMBL:CCQ43017.1};"]
[79140,"'CCDC28B'",237,278,236,250.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:0060271///cilium assembly+++GO:0030030///cell projection organization","coiled-coil domain containing 28B","[CC28B_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 28B;+++[E9PM03_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 28B {ECO:0000313|Ensembl:ENSP00000435036};+++[E9PM81_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 28B {ECO:0000313|Ensembl:ENSP00000431257};"]
[79173,"'C19orf57'",15,33,25,24.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00768///Nonsyndromic autosomal recessive mental retardation (NS-ARMR)",null,null,"GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0007275///multicellular organism development","chromosome 19 open reading frame 57","[CS057_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf57; AltName: Full=Pre-T/NK cell-associated protein 3B3;+++[K7EIN8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000464829}; Flags: Fragment;+++[K7ELK3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000466119}; Flags: Fragment;+++[K7EMZ7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000466723};+++[K7EP60_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000467241}; Flags: Fragment;+++[K7ERY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000468467}; Flags: Fragment;+++[L8EC49_HUMAN|Unreviewed]SubName: Full=Alternative protein C19orf57 {ECO:0000313|EMBL:CCQ42947.1};"]
[7920,"'ABHD16A'",488,432,440,453.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0016787///hydrolase activity+++GO:0004622///lysophospholipase activity+++GO:0047372///acylglycerol lipase activity+++GO:0005515///protein binding","GO:0052651///monoacylglycerol catabolic process+++GO:1905344///prostaglandin catabolic process","abhydrolase domain containing 16A","[ABHGA_HUMAN|Reviewed]RecName: Full=Protein ABHD16A {ECO:0000305}; EC=3.-.-.-; AltName: Full=Alpha/beta hydrolase domain-containing protein 16A {ECO:0000305}; Short=Abhydrolase domain-containing protein 16A {ECO:0000312|HGNC:HGNC:13921}; AltName: Full=HLA-B-associated transcript 5; AltName: Full=Protein G5;+++[A0A0G2JI89_HUMAN|Unreviewed]SubName: Full=Protein ABHD16A {ECO:0000313|Ensembl:ENSP00000396207}; Flags: Fragment;+++[A0A0G2JJD3_HUMAN|Unreviewed]SubName: Full=HLA-B associated transcript 5, isoform CRA_b {ECO:0000313|EMBL:EAX03483.1}; SubName: Full=Protein ABHD16A {ECO:0000313|Ensembl:ENSP00000406965};+++[A0A1U9X777_HUMAN|Unreviewed]SubName: Full=ABHD16A {ECO:0000313|EMBL:AQY76644.1};+++[B3KNX9_HUMAN|Unreviewed]SubName: Full=HLA-B associated transcript 5, isoform CRA_a {ECO:0000313|EMBL:EAX03482.1}; SubName: Full=cDNA FLJ30693 fis, clone FCBBF2000685, highly similar to HLA-B-associated transcript 5 {ECO:0000313|EMBL:BAG51491.1}; SubName: Full=cDNA FLJ50806, highly similar to HLA-B-associated transcript 5 {ECO:0000313|EMBL:BAH12526.1};+++[F2Z3G6_HUMAN|Unreviewed]SubName: Full=Protein ABHD16A {ECO:0000313|Ensembl:ENSP00000418331};+++[F2Z3H2_HUMAN|Unreviewed]SubName: Full=Protein ABHD16A {ECO:0000313|Ensembl:ENSP00000418170};+++[F2Z3Q3_HUMAN|Unreviewed]SubName: Full=Protein ABHD16A {ECO:0000313|Ensembl:ENSP00000417566};"]
[7936,"'NELFE'",1101,1054,1016,1057,{"$nulls":4},"GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0032021///NELF complex+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body","GO:0003676///nucleic acid binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0003746///translation elongation factor activity+++GO:0005515///protein binding","GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:0006414///translational elongation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","negative elongation factor complex member E","[NELFE_HUMAN|Reviewed]RecName: Full=Negative elongation factor E; Short=NELF-E; AltName: Full=RNA-binding protein RD;+++[A0A0A0MSN9_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|Ensembl:ENSP00000397914}; Flags: Fragment;+++[A0A0A0MT02_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|Ensembl:ENSP00000409389}; Flags: Fragment;+++[A0A0G2JI50_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|Ensembl:ENSP00000395175}; Flags: Fragment;+++[A0A1U9X830_HUMAN|Unreviewed]SubName: Full=NELFE {ECO:0000313|EMBL:AQY76952.1};+++[A2ABK4_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|Ensembl:ENSP00000394340}; Flags: Fragment;+++[B7Z6T4_HUMAN|Unreviewed]SubName: Full=RD RNA binding protein, isoform CRA_a {ECO:0000313|EMBL:EAX03551.1}; SubName: Full=cDNA FLJ56553, highly similar to Negative elongation factor E {ECO:0000313|EMBL:BAH13370.1};+++[E7ENC7_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|Ensembl:ENSP00000420205};+++[E7EWR7_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|Ensembl:ENSP00000419183};+++[E9PD43_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|Ensembl:ENSP00000414029}; Flags: Fragment;+++[H9ZYJ1_HUMAN|Unreviewed]SubName: Full=Negative elongation factor E {ECO:0000313|EMBL:AFH41798.1};"]
[79567,"'RIPOR1'",2856,3484,3178,3172.66666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0012506///vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0031252///cell leading edge+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0071889///14-3-3 protein binding","GO:0030335///positive regulation of cell migration+++GO:0009611///response to wounding+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:1990869///cellular response to chemokine+++GO:0090316///positive regulation of intracellular protein transport+++GO:2001107///negative regulation of Rho guanyl-nucleotide exchange factor activity+++GO:0034067///protein localization to Golgi apparatus+++GO:0051683///establishment of Golgi localization+++GO:0007266///Rho protein signal transduction+++GO:0009267///cellular response to starvation","RHO family interacting cell polarization regulator 1","[RIPR1_HUMAN|Reviewed]RecName: Full=Rho family-interacting cell polarization regulator 1;+++[A0A0A0MTL6_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000443568};+++[A0A0G2JLA4_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000455239}; Flags: Fragment;+++[H3BMG9_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000454376}; Flags: Fragment;+++[H3BP86_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000455200}; Flags: Fragment;+++[H3BQI5_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000455795}; Flags: Fragment;+++[H3BS40_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000456525}; Flags: Fragment;+++[H3BSV5_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000456893}; Flags: Fragment;+++[H3BSX9_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000456924}; Flags: Fragment;+++[H3BU12_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000457419}; Flags: Fragment;+++[H3BUP6_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000457739}; Flags: Fragment;+++[H3BV02_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 1 {ECO:0000313|Ensembl:ENSP00000457888}; Flags: Fragment;"]
[79582,"'SPAG16'",220.64,219.22,200,213.286666666667,"04910///Insulin signaling pathway+++04137///Mitophagy - animal+++04066///HIF-1 signaling pathway+++04010///MAPK signaling pathway+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:1990716///axonemal central apparatus+++GO:0005856///cytoskeleton+++GO:0005930///axoneme+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0031514///motile cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection","GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003727///single-stranded RNA binding+++GO:0042802///identical protein binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000166///nucleotide binding","GO:0060271///cilium assembly+++GO:0030030///cell projection organization+++GO:0035082///axoneme assembly+++GO:0007288///sperm axoneme assembly","sperm associated antigen 16","[SPG16_HUMAN|Reviewed]RecName: Full=Sperm-associated antigen 16 protein; AltName: Full=Pf20 protein homolog;+++[A0A0A0MQX0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000272898};+++[A0A0C4DG20_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000390494};+++[B4DYB5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53372, highly similar to Sperm-associated antigen 16 protein {ECO:0000313|EMBL:BAG63677.1};+++[E7EWV3_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000400847};+++[E9PE90_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000404949};+++[F8WB32_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000385496};+++[F8WBQ0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000398926};+++[F8WBY1_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000411077};+++[H0Y811_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 16 protein {ECO:0000313|Ensembl:ENSP00000416600}; Flags: Fragment;+++[Q4G1A2_HUMAN|Unreviewed]SubName: Full=SPAG16 protein {ECO:0000313|EMBL:AAH25379.1};+++[Q53QP6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PF20 {ECO:0000313|EMBL:AAY24242.1}; Flags: Fragment;+++[Q53R35_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PF20 {ECO:0000313|EMBL:AAX93063.1}; Flags: Fragment;+++[Q53RF0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PF20 {ECO:0000313|EMBL:AAX93125.1}; Flags: Fragment;+++[Q53RV6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PF20 {ECO:0000313|EMBL:AAX93264.1}; Flags: Fragment;+++[Q53SC3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PF20 {ECO:0000313|EMBL:AAY24171.1}; Flags: Fragment;+++[Q53TF1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PF20 {ECO:0000313|EMBL:AAY14888.1}; Flags: Fragment;+++[Q53TL7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PF20 {ECO:0000313|EMBL:AAX93092.1}; Flags: Fragment;"]
[79613,"'TANGO6'",230,233,228,230.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0051213///dioxygenase activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding","GO:0010468///regulation of gene expression","transport and golgi organization 6 homolog","[TNG6_HUMAN|Reviewed]RecName: Full=Transport and Golgi organization protein 6 homolog; AltName: Full=Transmembrane and coiled-coil domain-containing protein 7;+++[B3KTB6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38014 fis, clone CTONG2012607 {ECO:0000313|EMBL:BAG53028.1};+++[J3KT80_HUMAN|Unreviewed]SubName: Full=Transport and Golgi organization protein 6 homolog {ECO:0000313|Ensembl:ENSP00000462846}; Flags: Fragment;+++[J3QL82_HUMAN|Unreviewed]SubName: Full=Transport and Golgi organization protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463426}; Flags: Fragment;"]
[79634,"'SCRN3'",311.98,320.01,325,318.996666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0016805///dipeptidase activity","GO:0006508///proteolysis+++GO:0006887///exocytosis","secernin 3","[SCRN3_HUMAN|Reviewed]RecName: Full=Secernin-3;+++[A0A1D5RMN9_HUMAN|Unreviewed]SubName: Full=Secernin-3 {ECO:0000313|Ensembl:ENSP00000394024}; Flags: Fragment;+++[C9JID8_HUMAN|Unreviewed]SubName: Full=Secernin-3 {ECO:0000313|Ensembl:ENSP00000396884}; Flags: Fragment;+++[C9JNS3_HUMAN|Unreviewed]SubName: Full=Secernin-3 {ECO:0000313|Ensembl:ENSP00000408376}; Flags: Fragment;+++[F8W0M9_HUMAN|Unreviewed]SubName: Full=Secernin-3 {ECO:0000313|Ensembl:ENSP00000446727}; Flags: Fragment;+++[F8WBX0_HUMAN|Unreviewed]SubName: Full=Secernin-3 {ECO:0000313|Ensembl:ENSP00000447307};+++[H9KVC8_HUMAN|Unreviewed]SubName: Full=Secernin-3 {ECO:0000313|Ensembl:ENSP00000402086}; Flags: Fragment;+++[Q0VDG5_HUMAN|Unreviewed]SubName: Full=SCRN3 protein {ECO:0000313|EMBL:AAI19685.1};"]
[79649,"'MAP7D3'",474,509,428.01,470.336666666667,{"$nulls":4},"GO:0005819///spindle+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015630///microtubule cytoskeleton+++GO:0005856///cytoskeleton","GO:0008017///microtubule binding+++GO:0015631///tubulin binding","GO:0046785///microtubule polymerization+++GO:0000226///microtubule cytoskeleton organization","MAP7 domain containing 3","[MA7D3_HUMAN|Reviewed]RecName: Full=MAP7 domain-containing protein 3;+++[A0A0A0MRP0_HUMAN|Unreviewed]SubName: Full=MAP7 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000359694}; Flags: Fragment;"]
[79672,"'FN3KRP'",208,147,170,175,{"$nulls":4},"GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0043687///post-translational protein modification+++GO:0016310///phosphorylation","fructosamine 3 kinase related protein","[KT3K_HUMAN|Reviewed]RecName: Full=Ketosamine-3-kinase; EC=2.7.1.-; AltName: Full=Fructosamine-3-kinase-related protein; Short=FN3K-RP; Short=FN3K-related protein;+++[A0A140VK84_HUMAN|Unreviewed]SubName: Full=Fructosamine-3-kinase-related protein, isoform CRA_a {ECO:0000313|EMBL:EAW89817.1}; SubName: Full=Testis secretory sperm-binding protein Li 211a {ECO:0000313|EMBL:AEE61221.1};+++[I3L139_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000458550};+++[I3L2G3_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000459653}; Flags: Fragment;+++[I3L2K8_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000459751}; Flags: Fragment;+++[I3L378_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000460243}; Flags: Fragment;+++[I3L3W5_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000460777}; Flags: Fragment;+++[I3L407_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000460869};+++[Q6FIG5_HUMAN|Unreviewed]SubName: Full=FN3KRP protein {ECO:0000313|EMBL:CAG38492.1};"]
[79692,"'ZNF322'",330,302,261,297.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0035326///enhancer binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity","GO:1902459///positive regulation of stem cell population maintenance+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 322","[ZN322_HUMAN|Reviewed]RecName: Full=Zinc finger protein 322; AltName: Full=Zinc finger protein 322A; AltName: Full=Zinc finger protein 388; AltName: Full=Zinc finger protein 489;+++[A0A024QZZ4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 322A, isoform CRA_a {ECO:0000313|EMBL:EAW55595.1};"]
[79713,"'IGFLR1'",32,27,41,33.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding",null,"IGF like family receptor 1","[IGFR1_HUMAN|Reviewed]RecName: Full=IGF-like family receptor 1; AltName: Full=Transmembrane protein 149; AltName: Full=U2 small nuclear RNA auxiliary factor 1-like 4; Flags: Precursor;+++[K7EL86_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000465962};+++[K7EQI5_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000467842}; Flags: Fragment;+++[K7ES44_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000468545};+++[K7ESC2_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000468644}; Flags: Fragment;+++[S4R3Z9_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000474913}; Flags: Fragment;+++[U3KQL9_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000476009}; Flags: Fragment;"]
[79733,"'E2F8'",5,2,2,3,{"$nulls":4},"GO:0005829///cytosol+++GO:0005667///transcription factor complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0003677///DNA binding","GO:0051726///regulation of cell cycle+++GO:0007049///cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0002040///sprouting angiogenesis+++GO:0060718///chorionic trophoblast cell differentiation+++GO:0060707///trophoblast giant cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0033301///cell cycle comprising mitosis without cytokinesis+++GO:0032466///negative regulation of cytokinesis+++GO:0032877///positive regulation of DNA endoreduplication+++GO:0001890///placenta development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0070365///hepatocyte differentiation","E2F transcription factor 8","[E2F8_HUMAN|Reviewed]RecName: Full=Transcription factor E2F8; Short=E2F-8;+++[E9PMT9_HUMAN|Unreviewed]SubName: Full=Transcription factor E2F8 {ECO:0000313|Ensembl:ENSP00000437326}; Flags: Fragment;"]
[79752,"'ZFAND1'",84,77,82,81,"04217///Necroptosis+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04144///Endocytosis","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01202///Cataract","M00412///ESCRT-III complex",null,"GO:0010494///cytoplasmic stress granule+++GO:0005737///cytoplasm","GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0070628///proteasome binding","GO:1903843///cellular response to arsenite ion+++GO:0034605///cellular response to heat+++GO:0071470///cellular response to osmotic stress+++GO:0090316///positive regulation of intracellular protein transport+++GO:0035617///stress granule disassembly+++GO:0034599///cellular response to oxidative stress","zinc finger AN1-type containing 1","[ZFAN1_HUMAN|Reviewed]RecName: Full=AN1-type zinc finger protein 1 {ECO:0000305}; AltName: Full=Zinc finger AN1-type-containing protein 1 {ECO:0000305};+++[E5RFE5_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000428927};+++[E5RFU1_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000427957}; Flags: Fragment;+++[E5RG60_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000427811}; Flags: Fragment;+++[E5RGE5_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000430214};+++[E5RHR9_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000428527}; Flags: Fragment;+++[E5RI74_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000429527};+++[E5RIH7_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000430719}; Flags: Fragment;+++[E5RIS3_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000428375};+++[E5RJ74_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000428278}; Flags: Fragment;+++[E5RK75_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000428101}; Flags: Fragment;+++[H0YBX7_HUMAN|Unreviewed]SubName: Full=AN1-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000430499}; Flags: Fragment;+++[Q05BD2_HUMAN|Unreviewed]SubName: Full=ZFAND1 protein {ECO:0000313|EMBL:AAH51857.1}; SubName: Full=Zinc finger, AN1-type domain 1, isoform CRA_d {ECO:0000313|EMBL:EAW87106.1}; SubName: Full=cDNA FLJ52833, highly similar to AN1-type zinc finger protein 1 {ECO:0000313|EMBL:BAG65013.1};"]
[79753,"'SNIP1'",201,235,193,209.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0031047///gene silencing by RNA+++GO:0006355///regulation of transcription, DNA-templated+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0007249///I-kappaB kinase/NF-kappaB signaling","Smad nuclear interacting protein 1","[SNIP1_HUMAN|Reviewed]RecName: Full=Smad nuclear-interacting protein 1; AltName: Full=FHA domain-containing protein SNIP1;+++[A0A1W2PRA0_HUMAN|Unreviewed]SubName: Full=Smad nuclear-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000492185};+++[B1AK66_HUMAN|Unreviewed]SubName: Full=Smad nuclear interacting protein 1 {ECO:0000313|EMBL:EAX07338.1}; SubName: Full=cDNA, FLJ96650, Homo sapiens Smad nuclear interacting protein (SNIP1), mRNA {ECO:0000313|EMBL:BAG37948.1};"]
[7978,"'MTERF1'",101,74,61,78.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding","GO:0032392///DNA geometric change+++GO:0006393///termination of mitochondrial transcription+++GO:0006353///DNA-templated transcription, termination+++GO:0007005///mitochondrion organization+++GO:0006355///regulation of transcription, DNA-templated","mitochondrial transcription termination factor 1","[MTEF1_HUMAN|Reviewed]RecName: Full=Transcription termination factor 1, mitochondrial; AltName: Full=Mitochondrial transcription termination factor 1; Short=mTERF; Short=mTERF1; Flags: Precursor;+++[B4DPR9_HUMAN|Unreviewed]SubName: Full=Transcription termination factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000384986}; SubName: Full=cDNA FLJ51270, highly similar to Transcription termination factor, mitochondrial {ECO:0000313|EMBL:BAG60681.1};+++[C9JE25_HUMAN|Unreviewed]SubName: Full=Transcription termination factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000395097}; Flags: Fragment;+++[C9JNM8_HUMAN|Unreviewed]SubName: Full=Transcription termination factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000402175}; Flags: Fragment;+++[C9JU79_HUMAN|Unreviewed]SubName: Full=Transcription termination factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000400966}; Flags: Fragment;"]
[7980,"'TFPI2'",151,172,179,167.333333333333,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005201///extracellular matrix structural constituent+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010466///negative regulation of peptidase activity+++GO:0071498///cellular response to fluid shear stress+++GO:0007596///blood coagulation+++GO:0010951///negative regulation of endopeptidase activity+++GO:0007599///hemostasis","tissue factor pathway inhibitor 2","[TFPI2_HUMAN|Reviewed]RecName: Full=Tissue factor pathway inhibitor 2; Short=TFPI-2; AltName: Full=Placental protein 5; Short=PP5; Flags: Precursor;+++[A4ZVU7_HUMAN|Unreviewed]SubName: Full=TFPI2 variant {ECO:0000313|EMBL:ABP02055.1}; Flags: Fragment;+++[H7C4A3_HUMAN|Unreviewed]SubName: Full=Tissue factor pathway inhibitor 2 {ECO:0000313|Ensembl:ENSP00000416370}; Flags: Fragment;"]
[79817,"'MOB3B'",31,33,41,35,{"$nulls":5},"GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0035330///regulation of hippo signaling","MOB kinase activator 3B","[MOB3B_HUMAN|Reviewed]RecName: Full=MOB kinase activator 3B; AltName: Full=Mob1 homolog 2b; AltName: Full=Mps one binder kinase activator-like 2B; Short=MOB kinase activator-like 2B;+++[L0R5C0_HUMAN|Unreviewed]SubName: Full=Alternative protein MOBKL2B {ECO:0000313|EMBL:CCO13774.1};"]
[79838,"'TMC5'",8,13,8,9.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00604///Deafness, autosomal dominant+++H00605///Deafness, autosomal recessive+++H00842///Epidermodysplasia verruciformis",null,null,"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0008381///mechanosensitive ion channel activity+++GO:0005216///ion channel activity","GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0006811///ion transport","transmembrane channel like 5","[TMC5_HUMAN|Reviewed]RecName: Full=Transmembrane channel-like protein 5;+++[B7Z5K3_HUMAN|Unreviewed]RecName: Full=Transmembrane channel-like protein {ECO:0000256|RuleBase:RU310713};+++[B7Z946_HUMAN|Unreviewed]RecName: Full=Transmembrane channel-like protein {ECO:0000256|RuleBase:RU310713};+++[F5GYU8_HUMAN|Unreviewed]RecName: Full=Transmembrane channel-like protein {ECO:0000256|RuleBase:RU310713};+++[H3BN68_HUMAN|Unreviewed]RecName: Full=Transmembrane channel-like protein {ECO:0000256|RuleBase:RU310713};+++[I3L0P3_HUMAN|Unreviewed]RecName: Full=Transmembrane channel-like protein {ECO:0000256|RuleBase:RU310713}; Flags: Fragment;+++[I3L469_HUMAN|Unreviewed]SubName: Full=Transmembrane channel-like protein 5 {ECO:0000313|Ensembl:ENSP00000461008}; Flags: Fragment;"]
[79853,"'TM4SF20'",0,1,0,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion",null,"GO:0045861///negative regulation of proteolysis","transmembrane 4 L six family member 20","[T4S20_HUMAN|Reviewed]RecName: Full=Transmembrane 4 L6 family member 20;+++[C9JES4_HUMAN|Unreviewed]SubName: Full=Transmembrane 4 L6 family member 20 {ECO:0000313|Ensembl:ENSP00000416565}; Flags: Fragment;"]
[79879,"'CCDC134'",198,255,239,230.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0016020///membrane","GO:0005515///protein binding",null,"coiled-coil domain containing 134","[CC134_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 134; Flags: Precursor;+++[B0QY51_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 134 {ECO:0000313|Ensembl:ENSP00000385803};+++[B4DRL0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50180 {ECO:0000313|EMBL:BAG61322.1};"]
[79894,"'ZNF672'",1386,1627,1246,1419.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 672","[ZN672_HUMAN|Reviewed]RecName: Full=Zinc finger protein 672;+++[D6RD56_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 672 {ECO:0000313|Ensembl:ENSP00000427021}; Flags: Fragment;+++[D6RH11_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 672 {ECO:0000313|Ensembl:ENSP00000426199}; Flags: Fragment;"]
[79917,"'MAGIX'",39,30,33,34,{"$nulls":7},"MAGI family member, X-linked","[MAGIX_HUMAN|Reviewed]RecName: Full=PDZ domain-containing protein MAGIX;+++[A0A024QZ18_HUMAN|Unreviewed]SubName: Full=PDZ domain containing, X chromosome, isoform CRA_a {ECO:0000313|EMBL:EAW50692.1}; SubName: Full=PDZ domain-containing protein MAGIX {ECO:0000313|Ensembl:ENSP00000481198};+++[A0A087WUY6_HUMAN|Unreviewed]SubName: Full=PDZ domain-containing protein MAGIX {ECO:0000313|Ensembl:ENSP00000479023};+++[A0A087WW28_HUMAN|Unreviewed]SubName: Full=PDZ domain-containing protein MAGIX {ECO:0000313|Ensembl:ENSP00000479878};+++[A0A087X1L4_HUMAN|Unreviewed]SubName: Full=PDZ domain-containing protein MAGIX {ECO:0000313|Ensembl:ENSP00000484294};+++[A0A087X263_HUMAN|Unreviewed]SubName: Full=PDZ domain-containing protein MAGIX {ECO:0000313|Ensembl:ENSP00000484729};+++[C9J123_HUMAN|Unreviewed]SubName: Full=PDZ domain-containing protein MAGIX {ECO:0000313|Ensembl:ENSP00000400147}; Flags: Fragment;"]
[79944,"'L2HGDH'",333.56,371.66,314.03,339.75,"00650///Butanoate metabolism","H01280///L-2-hydroxyglutaric aciduria (L2HGA)",null,"R03534///2-Hydroxyglutarate:(acceptor) 2-oxidoreductase   2-Hydroxyglutarate + FAD <=> 2-Oxoglutarate + FADH2","GO:0005743///mitochondrial inner membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0003973///(S)-2-hydroxy-acid oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0047545///2-hydroxyglutarate dehydrogenase activity","GO:0006103///2-oxoglutarate metabolic process+++GO:0055114///oxidation-reduction process+++GO:0044267///cellular protein metabolic process","L-2-hydroxyglutarate dehydrogenase","[L2HDH_HUMAN|Reviewed]RecName: Full=L-2-hydroxyglutarate dehydrogenase, mitochondrial; EC=1.1.99.2; AltName: Full=Duranin; Flags: Precursor;+++[C9JVN9_HUMAN|Unreviewed]SubName: Full=L-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000261699};+++[G3V272_HUMAN|Unreviewed]SubName: Full=L-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450494};+++[G3V3E2_HUMAN|Unreviewed]SubName: Full=L-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000451194};+++[G3V5S1_HUMAN|Unreviewed]SubName: Full=L-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000452483};"]
[79960,"'JADE1'",740,671,674,695,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0005829///cytosol+++GO:0000123///histone acetyltransferase complex+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0036064///ciliary basal body+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding","GO:0043984///histone H4-K16 acetylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0043982///histone H4-K8 acetylation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0043966///histone H3 acetylation+++GO:0006915///apoptotic process+++GO:0043983///histone H4-K12 acetylation+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0043981///histone H4-K5 acetylation","jade family PHD finger 1","[JADE1_HUMAN|Reviewed]RecName: Full=Protein Jade-1; AltName: Full=Jade family PHD finger protein 1; AltName: Full=PHD finger protein 17;+++[B4E2E2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53490, highly similar to Homo sapiens PHD finger protein 17 (PHF17), transcript variant L, mRNA {ECO:0000313|EMBL:BAG65104.1};+++[D6RAS5_HUMAN|Unreviewed]SubName: Full=Protein Jade-1 {ECO:0000313|Ensembl:ENSP00000421778};+++[D6RBB3_HUMAN|Unreviewed]SubName: Full=Protein Jade-1 {ECO:0000313|Ensembl:ENSP00000424280}; Flags: Fragment;+++[D6RC05_HUMAN|Unreviewed]SubName: Full=Protein Jade-1 {ECO:0000313|Ensembl:ENSP00000422445}; Flags: Fragment;+++[D6RCS1_HUMAN|Unreviewed]SubName: Full=Protein Jade-1 {ECO:0000313|Ensembl:ENSP00000425535}; Flags: Fragment;+++[D6RE74_HUMAN|Unreviewed]SubName: Full=Protein Jade-1 {ECO:0000313|Ensembl:ENSP00000426920}; Flags: Fragment;+++[D6RFK0_HUMAN|Unreviewed]SubName: Full=Protein Jade-1 {ECO:0000313|Ensembl:ENSP00000426590}; Flags: Fragment;+++[D6RGE7_HUMAN|Unreviewed]SubName: Full=Protein Jade-1 {ECO:0000313|Ensembl:ENSP00000421265}; Flags: Fragment;"]
[80003,"'PCNX2'",275,272,277,274.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process","pecanex 2","[PCX2_HUMAN|Reviewed]RecName: Full=Pecanex-like protein 2; AltName: Full=Pecanex homolog protein 2 {ECO:0000312|HGNC:HGNC:8736};+++[A0A024R3U7_HUMAN|Unreviewed]SubName: Full=Pecanex-like 2 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW69983.1};+++[A0A0A0MSK9_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000394703};+++[B3KNZ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30812 fis, clone FEBRA2001492, highly similar to Mus musculus pecanex-like 2 (Drosophila) (Pcnxl2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG51507.1};+++[E7EVZ6_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000430820};+++[H0YAR6_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000427962}; Flags: Fragment;+++[H0YAV6_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000428134}; Flags: Fragment;+++[H0YB15_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000428488}; Flags: Fragment;+++[H0YB30_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000428582}; Flags: Fragment;+++[H0YBD1_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000429231}; Flags: Fragment;+++[H0YBD6_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000429262}; Flags: Fragment;+++[H0YBF4_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 2 {ECO:0000313|Ensembl:ENSP00000429360}; Flags: Fragment;"]
[80013,"'MINDY3'",252,221,241,238,{"$nulls":4},"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0016807///cysteine-type carboxypeptidase activity+++GO:1990380///Lys48-specific deubiquitinase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0071108///protein K48-linked deubiquitination+++GO:0006508///proteolysis+++GO:0006915///apoptotic process","MINDY lysine 48 deubiquitinase 3","[MINY3_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase MINDY-3; EC=3.4.19.12; AltName: Full=Dermal papilla-derived protein 5; AltName: Full=Deubiquitinating enzyme MINDY-3; AltName: Full=Protein CARP;+++[X6R9S5_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase MINDY-3 {ECO:0000313|Ensembl:ENSP00000367275};+++[X6RC30_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase MINDY-3 {ECO:0000313|Ensembl:ENSP00000388661}; Flags: Fragment;+++[X6RC97_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase MINDY-3 {ECO:0000313|Ensembl:ENSP00000389883}; Flags: Fragment;"]
[80039,"'FAM106A'",0,0,4.53,1.51,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"family with sequence similarity 106 member A","[F106A_HUMAN|Reviewed]RecName: Full=Protein FAM106A;"]
[8013,"'NR4A3'",11,11,12,11.3333333333333,"05202///Transcriptional misregulation in cancer","H00053///Extraskeletal myxoid chondrosarcoma",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0042629///mast cell granule+++GO:0005667///transcription factor complex","GO:0004887///thyroid hormone receptor activity+++GO:0035497///cAMP response element binding+++GO:0008270///zinc ion binding+++GO:0035259///glucocorticoid receptor binding+++GO:0046872///metal ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003707///steroid hormone receptor activity+++GO:0035035///histone acetyltransferase binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0050885///neuromuscular process controlling balance+++GO:0007165///signal transduction+++GO:0009444///pyruvate oxidation+++GO:0043066///negative regulation of apoptotic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045444///fat cell differentiation+++GO:2000253///positive regulation of feeding behavior+++GO:0043303///mast cell degranulation+++GO:0031100///animal organ regeneration+++GO:0007369///gastrulation+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045333///cellular respiration+++GO:0038097///positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway+++GO:2000108///positive regulation of leukocyte apoptotic process+++GO:0007411///axon guidance+++GO:0030522///intracellular receptor signaling pathway+++GO:0060005///vestibular reflex+++GO:0042542///response to hydrogen peroxide+++GO:0044320///cellular response to leptin stimulus+++GO:0021766///hippocampus development+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0030534///adult behavior+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0097009///energy homeostasis+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0032765///positive regulation of mast cell cytokine production+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:1900625///positive regulation of monocyte aggregation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0042472///inner ear morphogenesis+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:0043434///response to peptide hormone+++GO:0001707///mesoderm formation+++GO:0048752///semicircular canal morphogenesis+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071870///cellular response to catecholamine stimulus+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0000122///negative regulation of transcription by RNA polymerase II","nuclear receptor subfamily 4 group A member 3","[NR4A3_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 4 group A member 3; AltName: Full=Mitogen-induced nuclear orphan receptor; AltName: Full=Neuron-derived orphan receptor 1; AltName: Full=Nuclear hormone receptor NOR-1;+++[A0A024R168_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4, group A, member 3, isoform CRA_c {ECO:0000313|EMBL:EAW58918.1};+++[A0A1D8GZE0_HUMAN|Unreviewed]SubName: Full=NR4A3/PIK3R1 fusion protein {ECO:0000313|EMBL:AOT85455.1}; Flags: Fragment;"]
[80145,"'THOC7'",362,276,305,314.333333333333,"03013///RNA transport",null,"M00405///THC complex+++M00406///TREX complex",null,"GO:0000445///THO complex part of transcription export complex+++GO:0005654///nucleoplasm+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0000347///THO complex+++GO:0000346///transcription export complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006406///mRNA export from nucleus+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0006405///RNA export from nucleus","THO complex 7","[THOC7_HUMAN|Reviewed]RecName: Full=THO complex subunit 7 homolog; AltName: Full=Functional spliceosome-associated protein 24; Short=fSAP24; AltName: Full=Ngg1-interacting factor 3-like protein 1-binding protein 1; Short=NIF3L1-binding protein 1; AltName: Full=hTREX30;+++[A0A024R332_HUMAN|Unreviewed]SubName: Full=Ngg1 interacting factor 3 like 1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW65421.1};+++[A0A024R341_HUMAN|Unreviewed]SubName: Full=Ngg1 interacting factor 3 like 1 binding protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW65420.1}; SubName: Full=THO complex subunit 7 homolog {ECO:0000313|Ensembl:ENSP00000418518};+++[F8WF22_HUMAN|Unreviewed]SubName: Full=THO complex subunit 7 homolog {ECO:0000313|Ensembl:ENSP00000419443}; Flags: Fragment;+++[H7C5E3_HUMAN|Unreviewed]SubName: Full=THO complex subunit 7 homolog {ECO:0000313|Ensembl:ENSP00000419682}; Flags: Fragment;"]
[80164,"'PRR36'",1237,1305,1339,1293.66666666667,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"proline rich 36","[PRR36_HUMAN|Reviewed]RecName: Full=Proline-rich protein 36 {ECO:0000312|HGNC:HGNC:26172};+++[A0A096LNU1_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 36 {ECO:0000313|Ensembl:ENSP00000485221}; Flags: Fragment;"]
[80207,"'OPA3'",986.84,1010.19,997.88,998.303333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion","GO:0042803///protein homodimerization activity","GO:0050896///response to stimulus+++GO:0019216///regulation of lipid metabolic process+++GO:0007601///visual perception+++GO:0040008///regulation of growth+++GO:0050905///neuromuscular process+++GO:0070584///mitochondrion morphogenesis","OPA3, outer mitochondrial membrane lipid metabolism regulator","[OPA3_HUMAN|Reviewed]RecName: Full=Optic atrophy 3 protein;+++[B4DK77_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57883, highly similar to Optic atrophy 3 protein {ECO:0000313|EMBL:BAG59089.1};"]
[80228,"'ORAI2'",1153.87,1133.97,1049.31,1112.38333333333,"04020///Calcium signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030426///growth cone","GO:0015279///store-operated calcium channel activity+++GO:0005515///protein binding","GO:0070588///calcium ion transmembrane transport+++GO:0002115///store-operated calcium entry","ORAI calcium release-activated calcium modulator 2","[ORAI2_HUMAN|Reviewed]RecName: Full=Protein orai-2; AltName: Full=CAP-binding protein complex-interacting protein 2; AltName: Full=Transmembrane protein 142B;+++[A0A024QYV6_HUMAN|Unreviewed]SubName: Full=Chromosome 7 open reading frame 19, isoform CRA_a {ECO:0000313|EMBL:EAW50248.1};+++[B4DUB4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58946, highly similar to Protein orai-2 {ECO:0000313|EMBL:BAG62276.1};+++[C9J2H9_HUMAN|Unreviewed]SubName: Full=Protein orai-2 {ECO:0000313|Ensembl:ENSP00000417407}; Flags: Fragment;+++[C9J5L2_HUMAN|Unreviewed]SubName: Full=Protein orai-2 {ECO:0000313|Ensembl:ENSP00000418464}; Flags: Fragment;+++[C9JQR7_HUMAN|Unreviewed]SubName: Full=Protein orai-2 {ECO:0000313|Ensembl:ENSP00000420178}; Flags: Fragment;+++[C9JUY6_HUMAN|Unreviewed]SubName: Full=Protein orai-2 {ECO:0000313|Ensembl:ENSP00000419416}; Flags: Fragment;"]
[80262,"'C16orf70'",271,277,273,273.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030672///synaptic vesicle membrane+++GO:0030425///dendrite+++GO:0005802///trans-Golgi network","GO:0005515///protein binding","GO:0043001///Golgi to plasma membrane protein transport","chromosome 16 open reading frame 70","[CP070_HUMAN|Reviewed]RecName: Full=UPF0183 protein C16orf70;+++[A0A024R6W4_HUMAN|Unreviewed]SubName: Full=Lin-10 homolog (C. elegans), isoform CRA_b {ECO:0000313|EMBL:EAW83076.1};+++[H3BRA5_HUMAN|Unreviewed]SubName: Full=UPF0183 protein C16orf70 {ECO:0000313|Ensembl:ENSP00000456154}; Flags: Fragment;+++[H3BS58_HUMAN|Unreviewed]SubName: Full=UPF0183 protein C16orf70 {ECO:0000313|Ensembl:ENSP00000456549}; Flags: Fragment;+++[H3BSG0_HUMAN|Unreviewed]SubName: Full=UPF0183 protein C16orf70 {ECO:0000313|Ensembl:ENSP00000456688}; Flags: Fragment;+++[J3QRI8_HUMAN|Unreviewed]SubName: Full=UPF0183 protein C16orf70 {ECO:0000313|Ensembl:ENSP00000464242}; Flags: Fragment;"]
[80309,"'SPHKAP'",0,5,3,2.66666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0010738///regulation of protein kinase A signaling","SPHK1 interactor, AKAP domain containing","[SPKAP_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein SPHKAP; AltName: Full=SPHK1-interactor and AKAP domain-containing protein; AltName: Full=Sphingosine kinase type 1-interacting protein;"]
[80323,"'CCDC68'",25,16,16,19,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0120103///centriolar subdistal appendage","GO:0005515///protein binding","GO:0008104///protein localization+++GO:0034454///microtubule anchoring at centrosome+++GO:0035556///intracellular signal transduction","coiled-coil domain containing 68","[CCD68_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 68; AltName: Full=Cutaneous T-cell lymphoma-associated antigen se57-1; Short=CTCL-associated antigen se57-1;+++[A0A024R2B9_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 68, isoform CRA_a {ECO:0000313|EMBL:EAW63014.1};+++[K7EN04_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 68 {ECO:0000313|Ensembl:ENSP00000466731}; Flags: Fragment;"]
[80351,"'TNKS2'",756,706,652,704.666666666667,{"$nulls":4},"GO:0000242///pericentriolar material+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005829///cytosol+++GO:0005635///nuclear envelope+++GO:0000781///chromosome, telomeric region+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0048471///perinuclear region of cytoplasm","GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0070213///protein auto-ADP-ribosylation+++GO:0006471///protein ADP-ribosylation+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:1904355///positive regulation of telomere capping+++GO:0040014///regulation of multicellular organism growth+++GO:0016055///Wnt signaling pathway+++GO:0035264///multicellular organism growth+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening+++GO:0000209///protein polyubiquitination+++GO:0070198///protein localization to chromosome, telomeric region","tankyrase 2","[TNKS2_HUMAN|Reviewed]RecName: Full=Tankyrase-2; Short=TANK2; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 6; Short=ARTD6; AltName: Full=Poly [ADP-ribose] polymerase 5B; AltName: Full=TNKS-2; AltName: Full=TRF1-interacting ankyrin-related ADP-ribose polymerase 2; AltName: Full=Tankyrase II; AltName: Full=Tankyrase-like protein; AltName: Full=Tankyrase-related protein;"]
[80714,"'PBX4'",17,28,23,22.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001741///XY body+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II","PBX homeobox 4","[PBX4_HUMAN|Reviewed]RecName: Full=Pre-B-cell leukemia transcription factor 4; AltName: Full=Homeobox protein PBX4;+++[H0YL59_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 4 {ECO:0000313|Ensembl:ENSP00000453069};"]
[80745,"'THUMPD2'",49,65,47,53.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0008168///methyltransferase activity+++GO:0016740///transferase activity+++GO:0016423///tRNA (guanine) methyltransferase activity+++GO:0003723///RNA binding","GO:0032259///methylation+++GO:0030488///tRNA methylation","THUMP domain containing 2","[THUM2_HUMAN|Reviewed]RecName: Full=THUMP domain-containing protein 2;+++[B4DP37_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56995, highly similar to THUMP domain-containing protein 2 {ECO:0000313|EMBL:BAG60449.1};+++[D6W593_HUMAN|Unreviewed]SubName: Full=THUMP domain containing 2, isoform CRA_b {ECO:0000313|EMBL:EAX00342.1};+++[H0YE26_HUMAN|Unreviewed]SubName: Full=THUMP domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000434844}; Flags: Fragment;+++[H7C5V1_HUMAN|Unreviewed]SubName: Full=THUMP domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000426202}; Flags: Fragment;+++[Q969Z2_HUMAN|Unreviewed]SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:AAL18604.1}; SubName: Full=cDNA FLJ25072 fis, clone CBL05716 {ECO:0000313|EMBL:BAB71581.1};"]
[80778,"'ZNF34'",61.17,84.07,80.65,75.2966666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 34","[ZNF34_HUMAN|Reviewed]RecName: Full=Zinc finger protein 34; AltName: Full=Zinc finger protein KOX32;+++[A0A0C4DG42_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 34 {ECO:0000313|Ensembl:ENSP00000396894};+++[E9PNZ6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 34 {ECO:0000313|Ensembl:ENSP00000437056}; Flags: Fragment;+++[E9PSD0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 34 {ECO:0000313|Ensembl:ENSP00000434049}; Flags: Fragment;"]
[80830,"'APOL6'",9,9,11,9.66666666666667,null,"H00626///Focal segmental glomerulosclerosis",null,null,"GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0008289///lipid binding+++GO:0005515///protein binding","GO:0006869///lipid transport+++GO:0042157///lipoprotein metabolic process","apolipoprotein L6","[APOL6_HUMAN|Reviewed]RecName: Full=Apolipoprotein L6; AltName: Full=Apolipoprotein L-VI; Short=ApoL-VI;+++[B3KTP4_HUMAN|Unreviewed]SubName: Full=Apolipoprotein L, 6 {ECO:0000313|EMBL:EAW60069.1}; SubName: Full=Apolipoprotein L6 {ECO:0000313|EMBL:ACN51253.1}; SubName: Full=cDNA FLJ38562 fis, clone HCHON2004002, highly similar to Apolipoprotein-L6 {ECO:0000313|EMBL:BAG53156.1};"]
[8091,"'HMGA2'",325.93,210,338,291.31,"05202///Transcriptional misregulation in cancer+++05206///MicroRNAs in cancer","H01640///Uterine leiomyoma",null,null,"GO:0035985///senescence-associated heterochromatin focus+++GO:0071141///SMAD protein complex+++GO:0032993///protein-DNA complex+++GO:0000228///nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0000785///chromatin+++GO:0005634///nucleus","GO:0031492///nucleosomal DNA binding+++GO:0035501///MH1 domain binding+++GO:0035497///cAMP response element binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008301///DNA binding, bending+++GO:0070742///C2H2 zinc finger domain binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046332///SMAD binding+++GO:0035500///MH2 domain binding+++GO:0008134///transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0003712///transcription coregulator activity+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0003680///AT DNA binding","GO:0002062///chondrocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000648///positive regulation of stem cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006284///base-excision repair+++GO:0051301///cell division+++GO:0010628///positive regulation of gene expression+++GO:0007275///multicellular organism development+++GO:0035988///chondrocyte proliferation+++GO:0009615///response to virus+++GO:0001837///epithelial to mesenchymal transition+++GO:0030261///chromosome condensation+++GO:2000036///regulation of stem cell population maintenance+++GO:0043066///negative regulation of apoptotic process+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining+++GO:2000773///negative regulation of cellular senescence+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0048333///mesodermal cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0003131///mesodermal-endodermal cell signaling+++GO:0035978///histone H2A-S139 phosphorylation+++GO:0045766///positive regulation of angiogenesis+++GO:0045444///fat cell differentiation+++GO:2000685///positive regulation of cellular response to X-ray+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:0048762///mesenchymal cell differentiation+++GO:0031052///chromosome breakage+++GO:0031507///heterochromatin assembly+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0043392///negative regulation of DNA binding+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0035987///endodermal cell differentiation+++GO:0006325///chromatin organization+++GO:0040008///regulation of growth+++GO:0007049///cell cycle+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0010564///regulation of cell cycle process+++GO:0048863///stem cell differentiation+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0071158///positive regulation of cell cycle arrest+++GO:2001038///regulation of cellular response to drug+++GO:0090402///oncogene-induced cell senescence+++GO:0043922///negative regulation by host of viral transcription+++GO:2000774///positive regulation of cellular senescence+++GO:0045944///positive regulation of transcription by RNA polymerase II","high mobility group AT-hook 2","[HMGA2_HUMAN|Reviewed]RecName: Full=High mobility group protein HMGI-C; AltName: Full=High mobility group AT-hook protein 2;+++[F5H2A4_HUMAN|Unreviewed]SubName: Full=High mobility group protein HMGI-C {ECO:0000313|Ensembl:ENSP00000377205};+++[F5H2U8_HUMAN|Unreviewed]SubName: Full=High mobility group protein HMGI-C {ECO:0000313|Ensembl:ENSP00000439317};+++[F5H6H0_HUMAN|Unreviewed]SubName: Full=High mobility group protein HMGI-C {ECO:0000313|Ensembl:ENSP00000437621};+++[H0YFY4_HUMAN|Unreviewed]SubName: Full=High mobility group protein HMGI-C {ECO:0000313|Ensembl:ENSP00000440919}; Flags: Fragment;+++[Q1M183_HUMAN|Unreviewed]SubName: Full=HMGA2e' {ECO:0000313|EMBL:AAU43855.1};+++[Q8IZX8_HUMAN|Unreviewed]SubName: Full=High-mobility group protein isoform C {ECO:0000313|EMBL:AAN64002.1}; Flags: Fragment;"]
[811,"'CALR'",47257,45011,43688,45318.6666666667,"04612///Antigen processing and presentation+++05142///Chagas disease (American trypanosomiasis)+++05166///HTLV-I infection+++04141///Protein processing in endoplasmic reticulum+++04145///Phagosome+++05163///Human cytomegalovirus infection","H01605///Myelofibrosis+++H01612///Essential thrombocytosis",null,null,"GO:0042824///MHC class I peptide loading complex+++GO:0005622///intracellular+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0030670///phagocytic vesicle membrane+++GO:0032991///protein-containing complex+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0005788///endoplasmic reticulum lumen+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0062023///collagen-containing extracellular matrix+++GO:0016529///sarcoplasmic reticulum+++GO:0005844///polysome+++GO:0009897///external side of plasma membrane+++GO:0071682///endocytic vesicle lumen+++GO:0001669///acrosomal vesicle+++GO:0005790///smooth endoplasmic reticulum+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0005635///nuclear envelope+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0042277///peptide binding+++GO:0005178///integrin binding+++GO:0001849///complement component C1q binding+++GO:0050681///androgen receptor binding+++GO:0030246///carbohydrate binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0003729///mRNA binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0042562///hormone binding+++GO:0005509///calcium ion binding+++GO:0005506///iron ion binding+++GO:0044183///protein binding involved in protein folding","GO:0051208///sequestering of calcium ion+++GO:0071285///cellular response to lithium ion+++GO:1901164///negative regulation of trophoblast cell migration+++GO:0033144///negative regulation of intracellular steroid hormone receptor signaling pathway+++GO:0006874///cellular calcium ion homeostasis+++GO:0006457///protein folding+++GO:0050766///positive regulation of phagocytosis+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0090398///cellular senescence+++GO:0042493///response to drug+++GO:0006355///regulation of transcription, DNA-templated+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0034504///protein localization to nucleus+++GO:0002502///peptide antigen assembly with MHC class I protein complex+++GO:0007283///spermatogenesis+++GO:0061077///chaperone-mediated protein folding+++GO:0040020///regulation of meiotic nuclear division+++GO:0045787///positive regulation of cell cycle+++GO:0050821///protein stabilization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2000510///positive regulation of dendritic cell chemotaxis+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0022417///protein maturation by protein folding+++GO:0032355///response to estradiol+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0030866///cortical actin cytoskeleton organization+++GO:0006611///protein export from nucleus+++GO:0006898///receptor-mediated endocytosis+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0071157///negative regulation of cell cycle arrest+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0045665///negative regulation of neuron differentiation+++GO:0017148///negative regulation of translation+++GO:0042981///regulation of apoptotic process+++GO:0033574///response to testosterone+++GO:0055007///cardiac muscle cell differentiation+++GO:0042921///glucocorticoid receptor signaling pathway+++GO:0036500///ATF6-mediated unfolded protein response+++GO:0010033///response to organic substance+++GO:0071310///cellular response to organic substance+++GO:0010595///positive regulation of endothelial cell migration","calreticulin","[CALR_HUMAN|Reviewed]RecName: Full=Calreticulin; AltName: Full=CRP55; AltName: Full=Calregulin; AltName: Full=Endoplasmic reticulum resident protein 60; Short=ERp60; AltName: Full=HACBP; AltName: Full=grp60; Flags: Precursor;+++[A0A0F7W2W6_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|EMBL:CRH09108.1}; Flags: Fragment;+++[A0A0F7WAP3_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|EMBL:CRH09109.1}; Flags: Fragment;+++[A0A142IK94_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|EMBL:AMR60713.1}; Flags: Fragment;+++[A0A142IKA1_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|EMBL:AMR60720.1}; Flags: Fragment;+++[A0A142IKA2_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|EMBL:AMR60721.1}; Flags: Fragment;+++[K7EJB9_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|Ensembl:ENSP00000465105}; Flags: Fragment;+++[K7EL50_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|Ensembl:ENSP00000465918}; Flags: Fragment;+++[K7ELE2_HUMAN|Unreviewed]SubName: Full=Calreticulin {ECO:0000313|Ensembl:ENSP00000466037}; Flags: Fragment;+++[V9HW88_HUMAN|Unreviewed]SubName: Full=Calreticulin, isoform CRA_b {ECO:0000313|EMBL:EAW84332.1}; SubName: Full=Epididymis secretory sperm binding protein Li 99n {ECO:0000313|EMBL:ACI46003.1};"]
[81493,"'SYNC'",287.72,229,234,250.24,{"$nulls":4},"GO:0005882///intermediate filament+++GO:0005737///cytoplasm+++GO:0031594///neuromuscular junction+++GO:0030018///Z disc+++GO:0005829///cytosol+++GO:0042383///sarcolemma+++GO:0048471///perinuclear region of cytoplasm","GO:0005198///structural molecule activity","GO:0045103///intermediate filament-based process","syncoilin, intermediate filament protein","[SYNCI_HUMAN|Reviewed]RecName: Full=Syncoilin; AltName: Full=Syncoilin intermediate filament 1; AltName: Full=Syncoilin-1;+++[C9JSS1_HUMAN|Unreviewed]SubName: Full=Syncoilin {ECO:0000313|Ensembl:ENSP00000401975}; Flags: Fragment;+++[C9JTN4_HUMAN|Unreviewed]SubName: Full=Syncoilin {ECO:0000313|Ensembl:ENSP00000387594}; Flags: Fragment;"]
[81551,"'STMN4'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0005794///Golgi apparatus","GO:0015631///tubulin binding","GO:0051493///regulation of cytoskeleton organization+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0007019///microtubule depolymerization+++GO:0031175///neuron projection development","stathmin 4","[STMN4_HUMAN|Reviewed]RecName: Full=Stathmin-4; AltName: Full=Stathmin-like protein B3; Short=RB3;+++[E5RIR6_HUMAN|Unreviewed]SubName: Full=Stathmin-4 {ECO:0000313|Ensembl:ENSP00000430699};+++[E7EVN3_HUMAN|Unreviewed]SubName: Full=Stathmin-4 {ECO:0000313|Ensembl:ENSP00000430389};"]
[81577,"'GFOD2'",557.03,584.98,483.23,541.746666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region","GO:0016491///oxidoreductase activity","GO:0030198///extracellular matrix organization+++GO:0055114///oxidation-reduction process","glucose-fructose oxidoreductase domain containing 2","[GFOD2_HUMAN|Reviewed]RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 2; EC=1.-.-.-; Flags: Precursor;+++[A0A087WT49_HUMAN|Unreviewed]SubName: Full=Glucose-fructose oxidoreductase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000477581};+++[A0A087WTD9_HUMAN|Unreviewed]SubName: Full=Glucose-fructose oxidoreductase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000477784};+++[A0A087X156_HUMAN|Unreviewed]SubName: Full=Glucose-fructose oxidoreductase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000483913}; Flags: Fragment;"]
[81611,"'ANP32E'",306,314,285,301.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0000812///Swr1 complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0042393///histone binding+++GO:0019212///phosphatase inhibitor activity","GO:0043086///negative regulation of catalytic activity+++GO:0043486///histone exchange+++GO:0006325///chromatin organization","acidic nuclear phosphoprotein 32 family member E","[AN32E_HUMAN|Reviewed]RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E; AltName: Full=LANP-like protein; Short=LANP-L;+++[B4E0D5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54218, highly similar to Acidic leucine-rich nuclear phosphoprotein 32 family member E {ECO:0000313|EMBL:BAG64397.1};+++[E9PI45_HUMAN|Unreviewed]SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E {ECO:0000313|Ensembl:ENSP00000436529}; Flags: Fragment;+++[E9PLC4_HUMAN|Unreviewed]SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E {ECO:0000313|Ensembl:ENSP00000435215};+++[E9PPH5_HUMAN|Unreviewed]SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E {ECO:0000313|Ensembl:ENSP00000432684}; Flags: Fragment;+++[H0YCE2_HUMAN|Unreviewed]SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E {ECO:0000313|Ensembl:ENSP00000431434}; Flags: Fragment;+++[Q5TB19_HUMAN|Unreviewed]SubName: Full=Acidic (Leucine-rich) nuclear phosphoprotein 32 family, member E {ECO:0000313|EMBL:CAI22807.1}; SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E {ECO:0000313|Ensembl:ENSP00000358110};+++[Q5TB25_HUMAN|Unreviewed]SubName: Full=Acidic (Leucine-rich) nuclear phosphoprotein 32 family, member E {ECO:0000313|EMBL:CAI22809.1}; SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member E {ECO:0000313|Ensembl:ENSP00000358111};"]
[8165,"'AKAP1'",252,259,216,242.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005741///mitochondrial outer membrane","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0034237///protein kinase A regulatory subunit binding","GO:0010738///regulation of protein kinase A signaling+++GO:0007596///blood coagulation","A-kinase anchoring protein 1","[AKAP1_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 1, mitochondrial; AltName: Full=A-kinase anchor protein 149 kDa; Short=AKAP 149 {ECO:0000303|PubMed:8769136}; AltName: Full=Dual specificity A-kinase-anchoring protein 1; Short=D-AKAP-1; AltName: Full=Protein kinase A-anchoring protein 1; Short=PRKA1; AltName: Full=Spermatid A-kinase anchor protein 84; Short=S-AKAP84 {ECO:0000303|PubMed:7499250}; Flags: Precursor;+++[A0A0G2JLF7_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000461418}; Flags: Fragment;+++[A0A140VK05_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 5 {ECO:0000313|EMBL:AEE61142.1};+++[B4DN86_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56047, highly similar to A kinase anchor protein 1, mitochondrial {ECO:0000313|EMBL:BAG60148.1};+++[I3L0K6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458164}; Flags: Fragment;+++[I3L0V5_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458370}; Flags: Fragment;+++[I3L0W0_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458378}; Flags: Fragment;+++[I3L2A2_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000459521}; Flags: Fragment;+++[I3L2N7_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000459808}; Flags: Fragment;+++[I3L364_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460209}; Flags: Fragment;+++[I3L3K1_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460514}; Flags: Fragment;+++[I3L3L9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460557}; Flags: Fragment;+++[I3L3V6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460762}; Flags: Fragment;+++[I3NI36_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000461854}; Flags: Fragment;"]
[81691,"'REXO5'",21,16,10,15.6666666666667,"03008///Ribosome biogenesis in eukaryotes",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0070062///extracellular exosome+++GO:0005730///nucleolus","GO:0003676///nucleic acid binding+++GO:0004527///exonuclease activity+++GO:0004518///nuclease activity+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis","RNA exonuclease 5","[REXO5_HUMAN|Reviewed]RecName: Full=RNA exonuclease 5 {ECO:0000312|HGNC:HGNC:24661}; EC=3.1.-.-; AltName: Full=Exonuclease NEF-sp;+++[A0A024R390_HUMAN|Unreviewed]SubName: Full=Exonuclease NEF-sp, isoform CRA_a {ECO:0000313|EMBL:EAW66841.1};+++[H3BM72_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000454262}; Flags: Fragment;+++[H3BPB2_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000455233}; Flags: Fragment;+++[H3BQ98_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000455677}; Flags: Fragment;+++[H3BQP3_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000455867}; Flags: Fragment;+++[H3BR13_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456030}; Flags: Fragment;+++[H3BRC7_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456182};+++[H3BRG1_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456227};+++[H3BSC5_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456643}; Flags: Fragment;+++[H3BSE4_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456666}; Flags: Fragment;+++[H3BUT7_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000457789}; Flags: Fragment;+++[H3BV93_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000458004}; Flags: Fragment;"]
[81855,"'SFXN3'",1758,1798,1794,1783.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0015075///ion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0055072///iron ion homeostasis+++GO:0006811///ion transport","sideroflexin 3","[SFXN3_HUMAN|Reviewed]RecName: Full=Sideroflexin-3;+++[A0A0A0MS41_HUMAN|Unreviewed]RecName: Full=Sideroflexin {ECO:0000256|RuleBase:RU362000};+++[A0A1P0AYU5_HUMAN|Unreviewed]RecName: Full=Sideroflexin {ECO:0000256|RuleBase:RU362000};+++[S4R3N9_HUMAN|Unreviewed]SubName: Full=Sideroflexin-3 {ECO:0000313|Ensembl:ENSP00000474564};"]
[81875,"'ISG20L2'",727.46,709.67,726.93,721.353333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0004518///nuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0042254///ribosome biogenesis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0006364///rRNA processing","interferon stimulated exonuclease gene 20 like 2","[I20L2_HUMAN|Reviewed]RecName: Full=Interferon-stimulated 20 kDa exonuclease-like 2; EC=3.1.-.-;"]
[8214,"'DGCR6'",0,13.25,6.56,6.60333333333333,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0005634///nucleus",null,"GO:0009887///animal organ morphogenesis+++GO:0007155///cell adhesion","DiGeorge syndrome critical region gene 6","[DGCR6_HUMAN|Reviewed]RecName: Full=Protein DGCR6; AltName: Full=DiGeorge syndrome critical region 6;+++[X5D7D2_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region 6 isoform D {ECO:0000313|EMBL:AHW56460.1}; Flags: Fragment;"]
[8241,"'RBM10'",1571,1844,1604,1673,null,"H00943///TARP syndrome",null,null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding+++GO:0035198///miRNA binding+++GO:0003723///RNA binding","GO:0008285///negative regulation of cell proliferation+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0008380///RNA splicing+++GO:0070935///3'-UTR-mediated mRNA stabilization+++GO:0042981///regulation of apoptotic process+++GO:0034391///regulation of smooth muscle cell apoptotic process+++GO:0006397///mRNA processing+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0008150///biological_process+++GO:0048025///negative regulation of mRNA splicing, via spliceosome","RNA binding motif protein 10","[RBM10_HUMAN|Reviewed]RecName: Full=RNA-binding protein 10 {ECO:0000305}; AltName: Full=G patch domain-containing protein 9; AltName: Full=RNA-binding motif protein 10; AltName: Full=RNA-binding protein S1-1 {ECO:0000250|UniProtKB:P70501}; Short=S1-1;+++[A0A0S2Z4W4_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 10 isoform 2 {ECO:0000313|EMBL:ALQ33870.1}; Flags: Fragment;+++[A0A0S2Z4X1_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 10 isoform 1 {ECO:0000313|EMBL:ALQ33869.1}; Flags: Fragment;+++[Q6PKH5_HUMAN|Unreviewed]SubName: Full=RBM10 protein {ECO:0000313|EMBL:AAH00681.1}; Flags: Fragment;+++[Q7Z3D7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686E2459 {ECO:0000313|EMBL:CAD97933.1};"]
[8269,"'TMEM187'",127,129,124,126.666666666667,{"$nulls":4},"GO:0030133///transport vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0008150///biological_process","transmembrane protein 187","[TM187_HUMAN|Reviewed]RecName: Full=Transmembrane protein 187; AltName: Full=Protein ITBA1;+++[C9JIP7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 187 {ECO:0000313|Ensembl:ENSP00000390108}; Flags: Fragment;+++[C9JV55_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 187 {ECO:0000313|Ensembl:ENSP00000412872}; Flags: Fragment;"]
[8291,"'DYSF'",326,319,261,302,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00594///Distal myopathy+++H00593///Limb-girdle muscular dystrophy (LGMD)+++H01974///Limb-girdle muscular dystrophy (LGMD) 2B+++H01965///Miyoshi myopathy+++H00566///Dysferlinopathies",null,null,"GO:0005770///late endosome+++GO:0070062///extracellular exosome+++GO:0098857///membrane microdomain+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0005769///early endosome+++GO:0042383///sarcolemma+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0030027///lamellipodium+++GO:0030315///T-tubule+++GO:0005874///microtubule+++GO:0030139///endocytic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005544///calcium-dependent phospholipid binding+++GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding+++GO:0008289///lipid binding+++GO:0046872///metal ion binding+++GO:0005543///phospholipid binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0042177///negative regulation of protein catabolic process+++GO:0001525///angiogenesis+++GO:0043403///skeletal muscle tissue regeneration+++GO:0045444///fat cell differentiation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002281///macrophage activation involved in immune response+++GO:0010629///negative regulation of gene expression+++GO:1901842///negative regulation of high voltage-gated calcium channel activity+++GO:0045785///positive regulation of cell adhesion+++GO:0048747///muscle fiber development+++GO:0090279///regulation of calcium ion import+++GO:0002280///monocyte activation involved in immune response+++GO:0001778///plasma membrane repair+++GO:0033292///T-tubule organization+++GO:1902915///negative regulation of protein polyubiquitination+++GO:0006071///glycerol metabolic process+++GO:0019915///lipid storage+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0050765///negative regulation of phagocytosis+++GO:0006906///vesicle fusion+++GO:0050663///cytokine secretion+++GO:0071470///cellular response to osmotic stress","dysferlin","[DYSF_HUMAN|Reviewed]RecName: Full=Dysferlin; AltName: Full=Dystrophy-associated fer-1-like protein; AltName: Full=Fer-1-like protein 1;+++[E5KVZ4_HUMAN|Unreviewed]SubName: Full=Minidysferlin {ECO:0000313|EMBL:ADQ57464.1};+++[Q7Z6P1_HUMAN|Unreviewed]SubName: Full=Dysferlin {ECO:0000313|EMBL:CAD92859.1}; Flags: Fragment;"]
[8330,"'HIST1H2AK'",4,3,8,5,"05034///Alcoholism+++05322///Systemic lupus erythematosus+++04217///Necroptosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0000786///nucleosome+++GO:0005694///chromosome","GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006334///nucleosome assembly+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0051290///protein heterotetramerization+++GO:0000183///chromatin silencing at rDNA+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0007596///blood coagulation+++GO:0060968///regulation of gene silencing+++GO:0060964///regulation of gene silencing by miRNA+++GO:0006342///chromatin silencing+++GO:0032200///telomere organization+++GO:0044267///cellular protein metabolic process+++GO:0006325///chromatin organization+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0045814///negative regulation of gene expression, epigenetic","histone cluster 1 H2A family member k","[H2A1_HUMAN|Reviewed]RecName: Full=Histone H2A type 1; Short=H2A.1; AltName: Full=Histone H2A/ptl;+++[A4FTV9_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};"]
[8339,"'HIST1H2BG'",4,2,4,3.33333333333333,"05322///Systemic lupus erythematosus+++05203///Viral carcinogenesis+++05034///Alcoholism",{"$nulls":3},"GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000786///nucleosome+++GO:0005615///extracellular space","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0042802///identical protein binding","GO:0016567///protein ubiquitination+++GO:0002227///innate immune response in mucosa+++GO:0050830///defense response to Gram-positive bacterium+++GO:0019731///antibacterial humoral response+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0006334///nucleosome assembly","histone cluster 1 H2B family member g","[H2B1C_HUMAN|Reviewed]RecName: Full=Histone H2B type 1-C/E/F/G/I; AltName: Full=Histone H2B.1 A; AltName: Full=Histone H2B.a; Short=H2B/a; AltName: Full=Histone H2B.g; Short=H2B/g; AltName: Full=Histone H2B.h; Short=H2B/h; AltName: Full=Histone H2B.k; Short=H2B/k; AltName: Full=Histone H2B.l; Short=H2B/l;+++[B2R4S9_HUMAN|Unreviewed]RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};"]
[83451,"'ABHD11'",230,334.51,291.95,285.486666666667,null,"H01439///Williams-Beuren syndrome",null,null,"GO:0005739///mitochondrion+++GO:0005575///cellular_component","GO:0016787///hydrolase activity+++GO:0003674///molecular_function","GO:0008150///biological_process","abhydrolase domain containing 11","[ABHDB_HUMAN|Reviewed]RecName: Full=Protein ABHD11 {ECO:0000305}; EC=3.-.-.-; AltName: Full=Alpha/beta hydrolase domain-containing protein 11 {ECO:0000305}; Short=Abhydrolase domain-containing protein 11 {ECO:0000312|HGNC:HGNC:16407}; AltName: Full=Williams-Beuren syndrome chromosomal region 21 protein;+++[C9J7Q4_HUMAN|Unreviewed]SubName: Full=Protein ABHD11 {ECO:0000313|Ensembl:ENSP00000397666};+++[D3DXF2_HUMAN|Unreviewed]SubName: Full=Abhydrolase domain containing 11, isoform CRA_d {ECO:0000313|EMBL:EAW69646.1};+++[H0YC52_HUMAN|Unreviewed]SubName: Full=Protein ABHD11 {ECO:0000313|Ensembl:ENSP00000430937}; Flags: Fragment;+++[H7BZ58_HUMAN|Unreviewed]SubName: Full=Protein ABHD11 {ECO:0000313|Ensembl:ENSP00000387908}; Flags: Fragment;+++[H7C396_HUMAN|Unreviewed]SubName: Full=Protein ABHD11 {ECO:0000313|Ensembl:ENSP00000410536}; Flags: Fragment;"]
[83544,"'DNAL1'",301.88,235.44,259.01,265.443333333333,"05016///Huntington's disease","H00564///Primary ciliary dyskinesia",null,null,"GO:0005737///cytoplasm+++GO:0036157///outer dynein arm+++GO:0005856///cytoskeleton+++GO:0030286///dynein complex+++GO:0005874///microtubule+++GO:0042995///cell projection","GO:0003774///motor activity+++GO:0045504///dynein heavy chain binding+++GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding","GO:0036158///outer dynein arm assembly","dynein axonemal light chain 1","[DNAL1_HUMAN|Reviewed]RecName: Full=Dynein light chain 1, axonemal; Short=LC1 {ECO:0000250|UniProtKB:Q9XHH2};+++[G3V2M0_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000450744};+++[G3V389_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000451101}; Flags: Fragment;+++[G3V424_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000451547}; Flags: Fragment;+++[G3V5I4_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000452368}; Flags: Fragment;+++[H0YJD6_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000451264}; Flags: Fragment;+++[H0YM28_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000453439}; Flags: Fragment;"]
[8357,"'HIST1H3H'",1,4,0,1.66666666666667,"05034///Alcoholism+++05202///Transcriptional misregulation in cancer+++05322///Systemic lupus erythematosus","H01470///Giant cell tumor of bone",null,null,"GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0000788///nuclear nucleosome+++GO:0000786///nucleosome+++GO:0016020///membrane+++GO:0000228///nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex","GO:0003677///DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0045296///cadherin binding","GO:0032200///telomere organization+++GO:0000183///chromatin silencing at rDNA+++GO:0060964///regulation of gene silencing by miRNA+++GO:0051290///protein heterotetramerization+++GO:0006334///nucleosome assembly+++GO:0016567///protein ubiquitination+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0006325///chromatin organization+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0060968///regulation of gene silencing+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0044267///cellular protein metabolic process+++GO:0007596///blood coagulation","histone cluster 1 H3 family member h","[H31_HUMAN|Reviewed]RecName: Full=Histone H3.1; AltName: Full=Histone H3/a; AltName: Full=Histone H3/b; AltName: Full=Histone H3/c; AltName: Full=Histone H3/d; AltName: Full=Histone H3/f; AltName: Full=Histone H3/h; AltName: Full=Histone H3/i; AltName: Full=Histone H3/j; AltName: Full=Histone H3/k; AltName: Full=Histone H3/l;"]
[83658,"'DYNLRB1'",2417,2110,2140,2222.33333333333,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0097542///ciliary tip+++GO:0005868///cytoplasmic dynein complex+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0005874///microtubule+++GO:0030286///dynein complex+++GO:0036157///outer dynein arm","GO:0005515///protein binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0045505///dynein intermediate chain binding","GO:0035735///intraciliary transport involved in cilium assembly+++GO:0009416///response to light stimulus+++GO:0007018///microtubule-based movement+++GO:0007632///visual behavior","dynein light chain roadblock-type 1","[DLRB1_HUMAN|Reviewed]RecName: Full=Dynein light chain roadblock-type 1; AltName: Full=Bithoraxoid-like protein; Short=BLP; AltName: Full=Dynein light chain 2A, cytoplasmic; AltName: Full=Dynein-associated protein Km23; AltName: Full=Roadblock domain-containing protein 1;+++[B1AKR6_HUMAN|Unreviewed]SubName: Full=Dynein light chain roadblock-type 1 {ECO:0000313|Ensembl:ENSP00000363979};+++[B4DFR2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59194, moderately similar to Dynein light chain 2A, cytoplasmic {ECO:0000313|EMBL:BAG57523.1};"]
[8367,"'HIST1H4E'",0,1,0,0.333333333333333,"05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus+++05034///Alcoholism",{"$nulls":3},"GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006352///DNA-templated transcription, initiation+++GO:0006334///nucleosome assembly","histone cluster 1 H4 family member e","[H4_HUMAN|Reviewed]RecName: Full=Histone H4;+++[B2R4R0_HUMAN|Unreviewed]RecName: Full=Histone H4 {ECO:0000256|RuleBase:RU000528};"]
[83714,"'NRIP2'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0004190///aspartic-type endopeptidase activity","GO:0006508///proteolysis","nuclear receptor interacting protein 2","[NRIP2_HUMAN|Reviewed]RecName: Full=Nuclear receptor-interacting protein 2;+++[F5H065_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000438338}; Flags: Fragment;+++[F5H2G5_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000446283}; Flags: Fragment;"]
[83743,"'GRWD1'",436,531,450,472.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0032991///protein-containing complex","GO:0003688///DNA replication origin binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0042393///histone binding+++GO:0003682///chromatin binding","GO:0006334///nucleosome assembly+++GO:0006337///nucleosome disassembly+++GO:0006260///DNA replication","glutamate rich WD repeat containing 1","[GRWD1_HUMAN|Reviewed]RecName: Full=Glutamate-rich WD repeat-containing protein 1;+++[L8EB83_HUMAN|Unreviewed]SubName: Full=Alternative protein GRWD1 {ECO:0000313|EMBL:CCQ43748.1};+++[M0QX71_HUMAN|Unreviewed]SubName: Full=Glutamate-rich WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000468943}; Flags: Fragment;"]
[83857,"'TMTC1'",2560,2485,2097,2380.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0006396///RNA processing","transmembrane and tetratricopeptide repeat containing 1","[TMTC1_HUMAN|Reviewed]RecName: Full=Transmembrane and TPR repeat-containing protein 1;+++[F8VTQ9_HUMAN|Unreviewed]SubName: Full=Transmembrane and TPR repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000448112};+++[F8VXU8_HUMAN|Unreviewed]SubName: Full=Transmembrane and TPR repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000449043};+++[H0YIB9_HUMAN|Unreviewed]SubName: Full=Transmembrane and TPR repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000449054}; Flags: Fragment;+++[Q5K675_HUMAN|Unreviewed]SubName: Full=Osteoligament factor {ECO:0000313|EMBL:AAQ04260.1};"]
[83882,"'TSPAN10'",12297,12648,10525,11823.3333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0019899///enzyme binding","GO:0072594///establishment of protein localization to organelle+++GO:0007166///cell surface receptor signaling pathway","tetraspanin 10","[TSN10_HUMAN|Reviewed]RecName: Full=Tetraspanin-10; Short=Tspan-10; AltName: Full=Oculospanin;+++[A0A087WWT4_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[A0A087X235_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[F1T0E7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[F1T0E8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[Q6PJ65_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};"]
[83940,"'TATDN1'",90,90,66,82,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0008296///3'-5'-exodeoxyribonuclease activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0006259///DNA metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","TatD DNase domain containing 1","[TATD1_HUMAN|Reviewed]RecName: Full=Putative deoxyribonuclease TATDN1; EC=3.1.21.-; AltName: Full=Hepatocarcinoma high expression protein;+++[A0A0D9SGD3_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000487380};+++[E5RG17_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000430274}; Flags: Fragment;+++[E5RG62_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000427807}; Flags: Fragment;+++[E5RGF2_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000430201};+++[E5RH86_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000429831};+++[E5RI69_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000429541};+++[E5RID7_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000430756};+++[E5RJY6_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000431052};+++[E5RK70_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000428109}; Flags: Fragment;+++[G5EA19_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000428609}; SubName: Full=TatD DNase domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW92065.1};+++[H0YBX2_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000430481}; Flags: Fragment;+++[U3KQS5_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN1 {ECO:0000313|Ensembl:ENSP00000476180};"]
[83990,"'BRIP1'",39.03,56.94,43.53,46.5,"03440///Homologous recombination+++03460///Fanconi anemia pathway","H00238///Fanconi anemia",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0020037///heme binding+++GO:0005515///protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006281///DNA repair+++GO:0000117///regulation of transcription involved in G2/M transition of mitotic cell cycle","BRCA1 interacting protein C-terminal helicase 1","[FANCJ_HUMAN|Reviewed]RecName: Full=Fanconi anemia group J protein; Short=Protein FACJ; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase BRIP1; AltName: Full=BRCA1-associated C-terminal helicase 1; AltName: Full=BRCA1-interacting protein C-terminal helicase 1; Short=BRCA1-interacting protein 1;+++[C9IYH8_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000392202}; Flags: Fragment;+++[C9IYR0_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000400576}; Flags: Fragment;+++[C9JMP6_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000408605}; Flags: Fragment;+++[F8VZL7_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000447332}; Flags: Fragment;+++[H7C4B6_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000416569}; Flags: Fragment;+++[J3KS24_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000462274}; Flags: Fragment;+++[J3QKX0_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000463272}; Flags: Fragment;+++[J3QQP5_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000463827}; Flags: Fragment;+++[J3QSE8_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000464654};+++[M0QZP0_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000470673}; Flags: Fragment;+++[Q9BXM4_HUMAN|Unreviewed]SubName: Full=Transcription factor BACH1t {ECO:0000313|EMBL:AAK08197.1}; Flags: Fragment;"]
[84060,"'RBM48'",84,59,70,71,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding",null,"RNA binding motif protein 48","[RBM48_HUMAN|Reviewed]RecName: Full=RNA-binding protein 48;+++[A0PJB1_HUMAN|Unreviewed]SubName: Full=C7orf64 protein {ECO:0000313|EMBL:AAH20919.1}; Flags: Fragment;+++[C9J787_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 48 {ECO:0000313|Ensembl:ENSP00000418333}; Flags: Fragment;"]
[84079,"'ANKRD27'",193,222,224,213,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030659///cytoplasmic vesicle membrane+++GO:0097422///tubular endosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0030133///transport vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0043005///neuron projection+++GO:0005768///endosome+++GO:0042470///melanosome+++GO:0005769///early endosome+++GO:0016020///membrane","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0048812///neuron projection morphogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0035646///endosome to melanosome transport+++GO:0035544///negative regulation of SNARE complex assembly+++GO:0010976///positive regulation of neuron projection development+++GO:0045022///early endosome to late endosome transport","ankyrin repeat domain 27","[ANR27_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 27; AltName: Full=VPS9 domain-containing protein;+++[K7EIH4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 27 {ECO:0000313|Ensembl:ENSP00000464751}; Flags: Fragment;+++[K7EIN0_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 27 {ECO:0000313|Ensembl:ENSP00000464819}; Flags: Fragment;+++[K7ELM1_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 27 {ECO:0000313|Ensembl:ENSP00000466138};+++[K7ENE0_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 27 {ECO:0000313|Ensembl:ENSP00000466905};+++[K7EPM2_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 27 {ECO:0000313|Ensembl:ENSP00000467447}; Flags: Fragment;+++[V9GYL8_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 27 {ECO:0000313|Ensembl:ENSP00000476897}; Flags: Fragment;"]
[84124,"'ZNF394'",201,190,180,190.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 394","[ZN394_HUMAN|Reviewed]RecName: Full=Zinc finger protein 394; AltName: Full=Zinc finger protein with KRAB and SCAN domains 14;"]
[84146,"'ZNF644'",437,415,434,428.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 644","[ZN644_HUMAN|Reviewed]RecName: Full=Zinc finger protein 644; AltName: Full=Zinc finger motif enhancer-binding protein 2; Short=Zep-2;+++[A0A087WZL9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 644 {ECO:0000313|Ensembl:ENSP00000482748};+++[A7E234_HUMAN|Unreviewed]SubName: Full=ZNF644 protein {ECO:0000313|EMBL:AAI50178.1};+++[L0R5F4_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF644 {ECO:0000313|EMBL:CCO13858.1};+++[Q569I6_HUMAN|Unreviewed]SubName: Full=ZNF644 protein {ECO:0000313|EMBL:AAH92462.1}; Flags: Fragment;+++[Q8NEI6_HUMAN|Unreviewed]SubName: Full=ZNF644 protein {ECO:0000313|EMBL:AAH31003.1}; Flags: Fragment;"]
[84172,"'POLR1B'",290,297,277,288,"01100///Metabolic pathways+++03020///RNA polymerase+++00230///Purine metabolism+++00240///Pyrimidine metabolism",null,"M00182///RNA polymerase I, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0035861///site of double-strand break+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000781///chromosome, telomeric region+++GO:0016604///nuclear body+++GO:0005736///RNA polymerase I complex+++GO:0005730///nucleolus+++GO:0005662///DNA replication factor A complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0016605///PML body","GO:0032549///ribonucleoside binding+++GO:0019903///protein phosphatase binding+++GO:0016779///nucleotidyltransferase activity+++GO:0019899///enzyme binding+++GO:0016740///transferase activity+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001054///RNA polymerase I activity+++GO:0003697///single-stranded DNA binding+++GO:0047485///protein N-terminus binding+++GO:0003684///damaged DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003690///double-stranded DNA binding+++GO:0031625///ubiquitin protein ligase binding","GO:0033683///nucleotide-excision repair, DNA incision+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0006260///DNA replication+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0036297///interstrand cross-link repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0017126///nucleologenesis+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0009303///rRNA transcription+++GO:0032201///telomere maintenance via semi-conservative replication+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0019985///translesion synthesis+++GO:0000722///telomere maintenance via recombination+++GO:0007004///telomere maintenance via telomerase+++GO:0070987///error-free translesion synthesis+++GO:0006281///DNA repair+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0006351///transcription, DNA-templated+++GO:0030491///heteroduplex formation+++GO:0006289///nucleotide-excision repair+++GO:0042276///error-prone translesion synthesis+++GO:2000001///regulation of DNA damage checkpoint+++GO:0051096///positive regulation of helicase activity+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0006312///mitotic recombination+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006298///mismatch repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006268///DNA unwinding involved in DNA replication+++GO:1900034///regulation of cellular response to heat+++GO:0006284///base-excision repair+++GO:0006310///DNA recombination+++GO:0006265///DNA topological change+++GO:0034502///protein localization to chromosome+++GO:0000723///telomere maintenance+++GO:0007566///embryo implantation","RNA polymerase I subunit B","[RPA2_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase I subunit RPA2; Short=RNA polymerase I subunit 2; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase I 135 kDa polypeptide; Short=RPA135;+++[B7Z1W6_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031}; EC=2.7.7.6 {ECO:0000256|RuleBase:RU363031};+++[C9JJG2_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000415754}; Flags: Fragment;+++[C9JS83_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000388577}; Flags: Fragment;+++[F8WAK7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000334589};+++[F8WBB9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000390973};+++[F8WCS3_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000390274};+++[F8WDS4_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000403094};+++[H7C0D9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000394408}; Flags: Fragment;+++[Q4QRK8_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH96748.1}; Flags: Fragment;+++[Q5TEJ0_HUMAN|Unreviewed]SubName: Full=Replication protein A 32 kDa subunit {ECO:0000313|Ensembl:ENSP00000413541}; Flags: Fragment;+++[Q5TEJ7_HUMAN|Unreviewed]SubName: Full=Replication protein A 32 kDa subunit {ECO:0000313|Ensembl:ENSP00000387649}; Flags: Fragment;+++[Q6DKI9_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH73857.1}; Flags: Fragment;+++[Q9BSR4_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH04882.4}; Flags: Fragment;"]
[84216,"'TMEM117'",1377,1043,1081,1167,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0003674///molecular_function","GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","transmembrane protein 117","[TM117_HUMAN|Reviewed]RecName: Full=Transmembrane protein 117;+++[F8VS00_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 117 {ECO:0000313|Ensembl:ENSP00000448595};+++[F8W1J2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 117 {ECO:0000313|Ensembl:ENSP00000446952};+++[H0YI63_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 117 {ECO:0000313|Ensembl:ENSP00000448657}; Flags: Fragment;+++[Q05C15_HUMAN|Unreviewed]SubName: Full=TMEM117 protein {ECO:0000313|EMBL:AAH30284.1};"]
[84236,"'RHBDD1'",351,322,307,326.666666666667,"04920///Adipocytokine signaling pathway+++04212///Longevity regulating pathway - worm+++05206///MicroRNAs in cancer+++04211///Longevity regulating pathway+++04910///Insulin signaling pathway+++04140///Autophagy - animal+++04022///cGMP-PKG signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04722///Neurotrophin signaling pathway+++04150///mTOR signaling pathway+++04068///FoxO signaling pathway+++04960///Aldosterone-regulated sodium reabsorption+++04151///PI3K-Akt signaling pathway+++04931///Insulin resistance+++04213///Longevity regulating pathway - multiple species+++04152///AMPK signaling pathway+++04930///Type II diabetes mellitus+++04932///Non-alcoholic fatty liver disease (NAFLD)",null,"M00676///PI3K-Akt signaling",null,"GO:0005789///endoplasmic reticulum membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity","GO:0031293///membrane protein intracellular domain proteolysis+++GO:0034644///cellular response to UV+++GO:0030154///cell differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:2000254///regulation of male germ cell proliferation+++GO:0051047///positive regulation of secretion+++GO:0048515///spermatid differentiation+++GO:0034620///cellular response to unfolded protein+++GO:0033619///membrane protein proteolysis+++GO:0036503///ERAD pathway+++GO:0043687///post-translational protein modification+++GO:0045732///positive regulation of protein catabolic process+++GO:0010954///positive regulation of protein processing+++GO:0007283///spermatogenesis+++GO:1904211///membrane protein proteolysis involved in retrograde protein transport, ER to cytosol+++GO:0006508///proteolysis+++GO:0006915///apoptotic process","rhomboid domain containing 1","[RHBL4_HUMAN|Reviewed]RecName: Full=Rhomboid-related protein 4; Short=RRP4; EC=3.4.21.105; AltName: Full=Rhomboid domain-containing protein 1; AltName: Full=Rhomboid-like protein 4;+++[A0A024R455_HUMAN|Unreviewed]SubName: Full=Rhomboid domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW70842.1};+++[B9A054_HUMAN|Unreviewed]SubName: Full=Rhomboid-related protein 4 {ECO:0000313|Ensembl:ENSP00000387269};+++[C9J1R4_HUMAN|Unreviewed]SubName: Full=Rhomboid-related protein 4 {ECO:0000313|Ensembl:ENSP00000400765}; Flags: Fragment;+++[C9J4C7_HUMAN|Unreviewed]SubName: Full=Rhomboid-related protein 4 {ECO:0000313|Ensembl:ENSP00000410384}; Flags: Fragment;+++[C9JAS2_HUMAN|Unreviewed]SubName: Full=Rhomboid-related protein 4 {ECO:0000313|Ensembl:ENSP00000397298}; Flags: Fragment;+++[C9JQK8_HUMAN|Unreviewed]SubName: Full=Rhomboid-related protein 4 {ECO:0000313|Ensembl:ENSP00000388847}; Flags: Fragment;+++[C9K011_HUMAN|Unreviewed]SubName: Full=Rhomboid-related protein 4 {ECO:0000313|Ensembl:ENSP00000399694}; Flags: Fragment;"]
[84261,"'FBXW9'",413,377,354,381.333333333333,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0070545///PeBoW complex+++GO:0005829///cytosol","GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0000209///protein polyubiquitination+++GO:0043687///post-translational protein modification","F-box and WD repeat domain containing 9","[FBXW9_HUMAN|Reviewed]RecName: Full=F-box/WD repeat-containing protein 9; AltName: Full=F-box and WD-40 domain-containing protein 9;+++[A0A024R7F0_HUMAN|Unreviewed]SubName: Full=F-box and WD-40 domain protein 9, isoform CRA_a {ECO:0000313|EMBL:EAW84297.1};+++[K7EL01_HUMAN|Unreviewed]SubName: Full=F-box/WD repeat-containing protein 9 {ECO:0000313|Ensembl:ENSP00000465854};"]
[84272,"'YIPF4'",228,193,176,199,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding",null,"Yip1 domain family member 4","[YIPF4_HUMAN|Reviewed]RecName: Full=Protein YIPF4; AltName: Full=YIP1 family member 4;+++[H7C0D5_HUMAN|Unreviewed]SubName: Full=Protein YIPF4 {ECO:0000313|Ensembl:ENSP00000394339}; Flags: Fragment;+++[H7C3X2_HUMAN|Unreviewed]SubName: Full=Protein YIPF4 {ECO:0000313|Ensembl:ENSP00000414267}; Flags: Fragment;"]
[84286,"'TMEM175'",707,738,766,737,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0010008///endosome membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane+++GO:0005768///endosome","GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity","GO:0006813///potassium ion transport+++GO:0090385///phagosome-lysosome fusion+++GO:0006811///ion transport+++GO:0035751///regulation of lysosomal lumen pH+++GO:0071805///potassium ion transmembrane transport","transmembrane protein 175","[TM175_HUMAN|Reviewed]RecName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000305}; AltName: Full=Transmembrane protein 175 {ECO:0000312|HGNC:HGNC:28709}; Short=hTMEM175 {ECO:0000303|PubMed:26317472, ECO:0000303|PubMed:28723891};+++[D3DVN5_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000423669};+++[D6RAJ5_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000421750}; Flags: Fragment;+++[D6RAU7_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000424746}; Flags: Fragment;+++[D6RBE5_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000424208}; Flags: Fragment;+++[D6RCD9_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000423751};+++[D6RDY8_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000425181}; Flags: Fragment;+++[D6RHV8_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000427626};+++[D6RIZ2_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000425763}; Flags: Fragment;+++[E7ETE6_HUMAN|Unreviewed]SubName: Full=Endosomal/lysosomal potassium channel TMEM175 {ECO:0000313|Ensembl:ENSP00000425867}; Flags: Fragment;"]
[84293,"'PRXL2A'",2218.24,2238,2013.8,2156.68,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0016209///antioxidant activity","GO:0055114///oxidation-reduction process+++GO:0098869///cellular oxidant detoxification+++GO:0045670///regulation of osteoclast differentiation","peroxiredoxin like 2A","[F213A_HUMAN|Reviewed]RecName: Full=Redox-regulatory protein FAM213A; AltName: Full=Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes; Short=Protein PAMM;"]
[84320,"'ACBD6'",450,437,406,431,"04137///Mitophagy - animal+++04140///Autophagy - animal","H02036///Combined pituitary hormone deficiency+++H01700///Hypopituitarism+++H00254///Growth hormone deficiency",null,null,"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008289///lipid binding+++GO:0000062///fatty-acyl-CoA binding","GO:0006637///acyl-CoA metabolic process","acyl-CoA binding domain containing 6","[ACBD6_HUMAN|Reviewed]RecName: Full=Acyl-CoA-binding domain-containing protein 6;+++[A0A024R915_HUMAN|Unreviewed]SubName: Full=Acyl-Coenzyme A binding domain containing 6, isoform CRA_a {ECO:0000313|EMBL:EAW91083.1};+++[A0A2R8Y544_HUMAN|Unreviewed]SubName: Full=Acyl-CoA-binding domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000494507};+++[B2RAA8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94802 {ECO:0000313|EMBL:BAG36805.1};"]
[84330,"'ZNF414'",426,448,446,440,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 414","[ZN414_HUMAN|Reviewed]RecName: Full=Zinc finger protein 414;+++[M0R0Q5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 414 {ECO:0000313|Ensembl:ENSP00000471378}; Flags: Fragment;+++[M0R1G8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 414 {ECO:0000313|Ensembl:ENSP00000471863}; Flags: Fragment;+++[M0R2Q9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 414 {ECO:0000313|Ensembl:ENSP00000472741};+++[M0R398_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 414 {ECO:0000313|Ensembl:ENSP00000473079}; Flags: Fragment;"]
[8443,"'GNPAT'",588,548,519,551.666666666667,"00564///Glycerophospholipid metabolism+++04146///Peroxisome","H00207///Rhizomelic chondrodysplasia punctata",null,"R01013///Acyl-CoA:glycerone-phosphate O-acyltransferase   Acyl-CoA + Glycerone phosphate <=> CoA + Acylglycerone phosphate","GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol+++GO:0031966///mitochondrial membrane+++GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016287///glycerone-phosphate O-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0005102///signaling receptor binding","GO:0044255///cellular lipid metabolic process+++GO:0008611///ether lipid biosynthetic process+++GO:0042594///response to starvation+++GO:0030913///paranodal junction assembly+++GO:0008654///phospholipid biosynthetic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0070542///response to fatty acid+++GO:0042552///myelination+++GO:0021587///cerebellum morphogenesis+++GO:0006625///protein targeting to peroxisome+++GO:0061024///membrane organization+++GO:0006631///fatty acid metabolic process+++GO:0007416///synapse assembly+++GO:0042493///response to drug+++GO:0007584///response to nutrient","glyceronephosphate O-acyltransferase","[GNPAT_HUMAN|Reviewed]RecName: Full=Dihydroxyacetone phosphate acyltransferase; Short=DAP-AT; Short=DHAP-AT; EC=2.3.1.42; AltName: Full=Acyl-CoA:dihydroxyacetonephosphateacyltransferase; AltName: Full=Glycerone-phosphate O-acyltransferase;+++[A0A2R8YH69_HUMAN|Unreviewed]SubName: Full=Dihydroxyacetone phosphate acyltransferase {ECO:0000313|Ensembl:ENSP00000496537};+++[Q5TBH6_HUMAN|Unreviewed]SubName: Full=Dihydroxyacetone phosphate acyltransferase {ECO:0000313|Ensembl:ENSP00000402811}; Flags: Fragment;+++[Q5TBH8_HUMAN|Unreviewed]SubName: Full=Dihydroxyacetone phosphate acyltransferase {ECO:0000313|Ensembl:ENSP00000411640}; Flags: Fragment;"]
[8445,"'DYRK2'",545,421,424,463.333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0000287///magnesium ion binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0030145///manganese ion binding+++GO:0000166///nucleotide binding","GO:0007224///smoothened signaling pathway+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0006915///apoptotic process+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0006468///protein phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016310///phosphorylation","dual specificity tyrosine phosphorylation regulated kinase 2","[DYRK2_HUMAN|Reviewed]RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 2; EC=2.7.12.1;+++[A0A0A0MR56_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 2 {ECO:0000313|Ensembl:ENSP00000324733}; Flags: Fragment;+++[F5GXG1_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 2 {ECO:0000313|Ensembl:ENSP00000440839}; Flags: Fragment;+++[F5H5L5_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 2 {ECO:0000313|Ensembl:ENSP00000443314}; Flags: Fragment;+++[L8ECA4_HUMAN|Unreviewed]SubName: Full=Alternative protein DYRK2 {ECO:0000313|EMBL:CCQ43222.1};"]
[84461,"'NEURL4'",646,723,620,663,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm","GO:0005515///protein binding",null,"neuralized E3 ubiquitin protein ligase 4","[NEUL4_HUMAN|Reviewed]RecName: Full=Neuralized-like protein 4;+++[I3L100_HUMAN|Unreviewed]SubName: Full=Neuralized-like protein 4 {ECO:0000313|Ensembl:ENSP00000458469}; Flags: Fragment;+++[I3L2W2_HUMAN|Unreviewed]SubName: Full=Neuralized-like protein 4 {ECO:0000313|Ensembl:ENSP00000459978};+++[I3L2Z9_HUMAN|Unreviewed]SubName: Full=Neuralized-like protein 4 {ECO:0000313|Ensembl:ENSP00000460062}; Flags: Fragment;+++[K7EPS7_HUMAN|Unreviewed]SubName: Full=Neuralized-like protein 4 {ECO:0000313|Ensembl:ENSP00000467514}; Flags: Fragment;"]
[84520,"'GON7'",91,88,65,81.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0000408///EKC/KEOPS complex","GO:0005515///protein binding","GO:0016567///protein ubiquitination","GON7, KEOPS complex subunit","[GON7_HUMAN|Reviewed]RecName: Full=EKC/KEOPS complex subunit GON7 {ECO:0000305};+++[A0A024R6M5_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 142, isoform CRA_a {ECO:0000313|EMBL:EAW81520.1};+++[H0YJA8_HUMAN|Unreviewed]SubName: Full=EKC/KEOPS complex subunit GON7 {ECO:0000313|Ensembl:ENSP00000451114}; Flags: Fragment;"]
[8454,"'CUL1'",1088,1041,926,1018.33333333333,"04350///TGF-beta signaling pathway+++05168///Herpes simplex infection+++04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway+++04120///Ubiquitin mediated proteolysis+++05200///Pathways in cancer+++04141///Protein processing in endoplasmic reticulum+++04111///Cell cycle - yeast+++04114///Oocyte meiosis+++04710///Circadian rhythm+++04310///Wnt signaling pathway+++04110///Cell cycle","H01613///Follicular lymphoma+++H01751///Weaver syndrome","M00380///SCF-BTRC complex+++M00387///SCF-FBW7 complex+++M00379///SCF-MET30 complex+++M00381///SCF-SKP2 complex+++M00382///SCF-FBS complex+++M00407///SCF-CDC4 complex+++M00411///SCF-GRR1 complex","R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:1990452///Parkin-FBXW7-Cul1 ubiquitin ligase complex+++GO:0019005///SCF ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding","GO:0051403///stress-activated MAPK cascade+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006915///apoptotic process+++GO:0016055///Wnt signaling pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010265///SCF complex assembly+++GO:0007050///cell cycle arrest+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006513///protein monoubiquitination+++GO:0008283///cell proliferation+++GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination+++GO:0016032///viral process+++GO:0000209///protein polyubiquitination+++GO:0006879///cellular iron ion homeostasis+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0009887///animal organ morphogenesis+++GO:0038061///NIK/NF-kappaB signaling+++GO:0070498///interleukin-1-mediated signaling pathway","cullin 1","[CUL1_HUMAN|Reviewed]RecName: Full=Cullin-1; Short=CUL-1;+++[A0A090N7U0_HUMAN|Unreviewed]SubName: Full=Cullin 1 {ECO:0000313|EMBL:EAL24422.1}; SubName: Full=Cullin 1, isoform CRA_b {ECO:0000313|EMBL:EAW80073.1};+++[A0A0C4DGX4_HUMAN|Unreviewed]SubName: Full=Cullin-1 {ECO:0000313|Ensembl:ENSP00000482123};+++[B3KTW0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38844 fis, clone MESAN2003662, highly similar to Cullin-1 {ECO:0000313|EMBL:BAG53222.1};+++[Q75MQ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CUL1 {ECO:0000313|EMBL:AAS02034.1}; Flags: Fragment;"]
[84617,"'TUBB6'",6357,5156,4879,5464,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection","H00679///Hypomyelinating leukodystrophy+++H00271///Polymicrogyria+++H01897///Oocyte maturation defect+++H01740///Macrothrombocytopenia+++H01579///Congenital symmetric circumferential skin creases+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01881///Complex cortical dysplasia with other brain malformations",null,null,"GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule","GO:0005200///structural constituent of cytoskeleton+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0003674///molecular_function","GO:0007010///cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0007017///microtubule-based process","tubulin beta 6 class V","[TBB6_HUMAN|Reviewed]RecName: Full=Tubulin beta-6 chain; AltName: Full=Tubulin beta class V;+++[B3KS31_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[B4E386_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52847, highly similar to Tubulin beta-6 chain {ECO:0000313|EMBL:BAG65398.1};+++[K7EJ64_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000465040};+++[K7EJZ4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000465386};+++[K7EK43_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000465448}; Flags: Fragment;+++[K7EL29_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000465891}; Flags: Fragment;+++[K7EN98_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000466849};+++[K7EPE5_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000467348};+++[K7EQT3_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000467969};+++[K7ERA8_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000468179};+++[K7ES63_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[K7ESM5_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[K7ESQ3_HUMAN|Unreviewed]SubName: Full=Tubulin beta-6 chain {ECO:0000313|Ensembl:ENSP00000468820};+++[Q2NKY5_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};"]
[84640,"'USP38'",653,717,645,671.666666666667,{"$nulls":5},"GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity","GO:0016579///protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006508///proteolysis","ubiquitin specific peptidase 38","[UBP38_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 38; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 38; AltName: Full=HP43.8KD; AltName: Full=Ubiquitin thioesterase 38; AltName: Full=Ubiquitin-specific-processing protease 38;+++[B3KSB9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ35970 fis, clone TESTI2013231, highly similar to Ubiquitin carboxyl-terminal hydrolase 38 (EC3.1.2.15) {ECO:0000313|EMBL:BAG52681.1};+++[H0Y9H5_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 38 {ECO:0000313|Ensembl:ENSP00000424158}; Flags: Fragment;"]
[8467,"'SMARCA5'",1491,1560,1479,1510,{"$nulls":4},"GO:0000793///condensed chromosome+++GO:0031213///RSF complex+++GO:0001650///fibrillar center+++GO:0031010///ISWI-type complex+++GO:0005654///nucleoplasm+++GO:0043596///nuclear replication fork+++GO:0005677///chromatin silencing complex+++GO:0005634///nucleus+++GO:0016589///NURF complex","GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0042393///histone binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding+++GO:0000166///nucleotide binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004386///helicase activity+++GO:0016787///hydrolase activity+++GO:0003677///DNA binding","GO:0045815///positive regulation of gene expression, epigenetic+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000183///chromatin silencing at rDNA+++GO:0006334///nucleosome assembly+++GO:0006338///chromatin remodeling+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0006333///chromatin assembly or disassembly+++GO:0016584///nucleosome positioning+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0006352///DNA-templated transcription, initiation+++GO:0006325///chromatin organization+++GO:0045893///positive regulation of transcription, DNA-templated","SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5","[SMCA5_HUMAN|Reviewed]RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; Short=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; EC=3.6.4.-; AltName: Full=Sucrose nonfermenting protein 2 homolog; Short=hSNF2H;+++[Q4W5G3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SMARCA5 {ECO:0000313|EMBL:AAY40965.1}; Flags: Fragment;+++[Q4W5H1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SMARCA5 {ECO:0000313|EMBL:AAY40920.1}; Flags: Fragment;"]
[84700,"'MYO18B'",8,7,5,6.66666666666667,null,"H00852///Klippel-Feil syndrome(KFS)",null,null,"GO:0030018///Z disc+++GO:0031941///filamentous actin+++GO:0030017///sarcomere+++GO:0005634///nucleus+++GO:0016461///unconventional myosin complex+++GO:0005737///cytoplasm+++GO:0016459///myosin complex","GO:0003774///motor activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0003779///actin binding","GO:0048739///cardiac muscle fiber development+++GO:0001701///in utero embryonic development+++GO:0001570///vasculogenesis","myosin XVIIIB","[MY18B_HUMAN|Reviewed]RecName: Full=Unconventional myosin-XVIIIb;+++[A0A024R1E2_HUMAN|Unreviewed]SubName: Full=Myosin XVIIIB, isoform CRA_c {ECO:0000313|EMBL:EAW59705.1};+++[A0A024R1G4_HUMAN|Unreviewed]SubName: Full=Myosin XVIIIB, isoform CRA_d {ECO:0000313|EMBL:EAW59708.1};+++[A0A2Q2TCQ6_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-XVIIIb {ECO:0000313|Ensembl:ENSP00000441301}; Flags: Fragment;+++[F5H6I8_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-XVIIIb {ECO:0000313|Ensembl:ENSP00000437587};+++[H0YGQ4_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-XVIIIb {ECO:0000313|Ensembl:ENSP00000444262}; Flags: Fragment;+++[L8EAK4_HUMAN|Unreviewed]SubName: Full=Alternative protein MYO18B {ECO:0000313|EMBL:CCQ43776.1};"]
[84727,"'SPSB2'",87,101,95,94.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex","GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0003674///molecular_function","GO:0035556///intracellular signal transduction+++GO:0008150///biological_process+++GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","splA/ryanodine receptor domain and SOCS box containing 2","[SPSB2_HUMAN|Reviewed]RecName: Full=SPRY domain-containing SOCS box protein 2; Short=SSB-2; AltName: Full=Gene-rich cluster protein C9;+++[E5RIC2_HUMAN|Unreviewed]SubName: Full=SPRY domain-containing SOCS box protein 2 {ECO:0000313|Ensembl:ENSP00000428458}; Flags: Fragment;"]
[84790,"'TUBA1C'",9343.1,8999.7,8909.98,9084.26,"04145///Phagosome+++04210///Apoptosis+++04540///Gap junction+++05130///Pathogenic Escherichia coli infection+++04530///Tight junction","H00271///Polymicrogyria+++H00268///Lissencephaly (LIS)+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0015630///microtubule cytoskeleton+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005881///cytoplasmic microtubule+++GO:0005856///cytoskeleton+++GO:0031982///vesicle+++GO:0005634///nucleus","GO:0003924///GTPase activity+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0005198///structural molecule activity","GO:0007017///microtubule-based process+++GO:0051301///cell division+++GO:0007010///cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0000226///microtubule cytoskeleton organization","tubulin alpha 1c","[TBA1C_HUMAN|Reviewed]RecName: Full=Tubulin alpha-1C chain; AltName: Full=Alpha-tubulin 6; AltName: Full=Tubulin alpha-6 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1C chain;+++[A0A1W2PQM2_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1C chain {ECO:0000313|Ensembl:ENSP00000492176};+++[B7Z1K5_HUMAN|Unreviewed]RecName: Full=Tubulin alpha chain {ECO:0000256|RuleBase:RU000352};+++[F5H5D3_HUMAN|Unreviewed]RecName: Full=Tubulin alpha chain {ECO:0000256|RuleBase:RU000352};+++[F8VRK1_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1C chain {ECO:0000313|Ensembl:ENSP00000448646};+++[F8VS66_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1C chain {ECO:0000313|Ensembl:ENSP00000448211};+++[H0YHV2_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1C chain {ECO:0000313|Ensembl:ENSP00000447910}; Flags: Fragment;+++[Q8N532_HUMAN|Unreviewed]SubName: Full=TUBA1C protein {ECO:0000313|EMBL:AAH33064.1};"]
[84792,"'FAM220A'",426,393,351,390,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus",null,null,"family with sequence similarity 220 member A","[F220A_HUMAN|Reviewed]RecName: Full=Protein FAM220A; AltName: Full=STAT3-interacting protein as a repressor;+++[A0A0C4DGP1_HUMAN|Unreviewed]SubName: Full=Protein FAM220A {ECO:0000313|Ensembl:ENSP00000464009};+++[E9PQC6_HUMAN|Unreviewed]SubName: Full=Protein FAM220A {ECO:0000313|Ensembl:ENSP00000436886}; Flags: Fragment;+++[E9PQY0_HUMAN|Unreviewed]SubName: Full=Protein FAM220A {ECO:0000313|Ensembl:ENSP00000432444}; Flags: Fragment;"]
[84864,"'RIOX2'",217,267,234,239.333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm","GO:0042802///identical protein binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0032452///histone demethylase activity+++GO:0051213///dioxygenase activity","GO:0042254///ribosome biogenesis+++GO:0055114///oxidation-reduction process+++GO:0016577///histone demethylation","ribosomal oxygenase 2","[RIOX2_HUMAN|Reviewed]RecName: Full=Ribosomal oxygenase 2 {ECO:0000312|HGNC:HGNC:19441}; AltName: Full=60S ribosomal protein L27a histidine hydroxylase; AltName: Full=Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA; EC=1.14.11.-; AltName: Full=Histone lysine demethylase MINA; AltName: Full=MYC-induced nuclear antigen; AltName: Full=Mineral dust-induced gene protein; AltName: Full=Nucleolar protein 52; AltName: Full=Ribosomal oxygenase MINA; Short=ROX;+++[D6RCB6_HUMAN|Unreviewed]SubName: Full=Ribosomal oxygenase 2 {ECO:0000313|Ensembl:ENSP00000423816}; Flags: Fragment;+++[H0Y8K4_HUMAN|Unreviewed]SubName: Full=Ribosomal oxygenase 2 {ECO:0000313|Ensembl:ENSP00000421347}; Flags: Fragment;+++[H0Y9L8_HUMAN|Unreviewed]SubName: Full=Ribosomal oxygenase 2 {ECO:0000313|Ensembl:ENSP00000424530}; Flags: Fragment;"]
[84865,"'CCDC142'",116.94,132.97,117.1,122.336666666667,{"$nulls":7},"coiled-coil domain containing 142","[CC142_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 142;+++[H7C450_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 142 {ECO:0000313|Ensembl:ENSP00000415532}; Flags: Fragment;"]
[84888,"'SPPL2A'",473.08,441.82,439.03,451.31,{"$nulls":4},"GO:0032040///small-subunit processome+++GO:0005770///late endosome+++GO:0030660///Golgi-associated vesicle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0034457///Mpp10 complex+++GO:0016020///membrane+++GO:0005840///ribosome+++GO:0071458///integral component of cytoplasmic side of endoplasmic reticulum membrane+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005730///nucleolus+++GO:0031902///late endosome membrane+++GO:0005768///endosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0030684///preribosome+++GO:0070062///extracellular exosome+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane","GO:0042803///protein homodimerization activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0019843///rRNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0030515///snoRNA binding+++GO:0016787///hydrolase activity","GO:0031293///membrane protein intracellular domain proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0033619///membrane protein proteolysis+++GO:0050776///regulation of immune response+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing+++GO:0006508///proteolysis","signal peptide peptidase like 2A","[SPP2A_HUMAN|Reviewed]RecName: Full=Signal peptide peptidase-like 2A {ECO:0000303|PubMed:15385547, ECO:0000312|HGNC:HGNC:30227}; Short=SPP-like 2A {ECO:0000303|PubMed:15385547}; Short=SPPL2a {ECO:0000303|PubMed:15385547}; EC=3.4.23.-; AltName: Full=Intramembrane protease 3 {ECO:0000303|PubMed:12139484}; Short=IMP-3 {ECO:0000303|PubMed:12139484}; AltName: Full=Presenilin-like protein 2; Flags: Precursor;+++[H0YNA2_HUMAN|Unreviewed]SubName: Full=Signal peptide peptidase-like 2A {ECO:0000313|Ensembl:ENSP00000453927}; Flags: Fragment;+++[H0YNA7_HUMAN|Unreviewed]SubName: Full=Signal peptide peptidase-like 2A {ECO:0000313|Ensembl:ENSP00000453932}; Flags: Fragment;"]
[84908,"'FAM136A'",447,377,417,413.666666666667,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"family with sequence similarity 136 member A","[F136A_HUMAN|Reviewed]RecName: Full=Protein FAM136A;+++[B0AZT6_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79526 {ECO:0000313|EMBL:BAF98768.1};+++[C9J2Y4_HUMAN|Unreviewed]SubName: Full=Protein FAM136A {ECO:0000313|Ensembl:ENSP00000391468};+++[C9JF51_HUMAN|Unreviewed]SubName: Full=Protein FAM136A {ECO:0000313|Ensembl:ENSP00000390840}; Flags: Fragment;+++[E7EQY1_HUMAN|Unreviewed]SubName: Full=Protein FAM136A {ECO:0000313|Ensembl:ENSP00000397269};"]
[84924,"'ZNF566'",120,131,138,129.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 566","[ZN566_HUMAN|Reviewed]RecName: Full=Zinc finger protein 566;+++[B4DRR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52734, highly similar to Zinc finger protein 566 {ECO:0000313|EMBL:BAG61378.1};+++[C9J2D3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 566 {ECO:0000313|Ensembl:ENSP00000400651}; Flags: Fragment;+++[C9J6X1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 566 {ECO:0000313|Ensembl:ENSP00000411526}; Flags: Fragment;+++[K7EQC1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 566 {ECO:0000313|Ensembl:ENSP00000467764}; Flags: Fragment;"]
[84942,"'WDR73'",245,269,241,251.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005819///spindle+++GO:0005737///cytoplasm+++GO:0032154///cleavage furrow","GO:0003674///molecular_function","GO:0043066///negative regulation of apoptotic process+++GO:0006997///nucleus organization+++GO:0031122///cytoplasmic microtubule organization","WD repeat domain 73","[WDR73_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 73;+++[B3KP50_HUMAN|Unreviewed]SubName: Full=WD repeat domain 73, isoform CRA_a {ECO:0000313|EMBL:EAX01945.1}; SubName: Full=cDNA FLJ31167 fis, clone KIDNE1000145, highly similar to Homo sapiens WD repeat domain 73 (WDR73), mRNA {ECO:0000313|EMBL:BAG51562.1};+++[H0YLH0_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 73 {ECO:0000313|Ensembl:ENSP00000453204}; Flags: Fragment;+++[H0YMT3_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 73 {ECO:0000313|Ensembl:ENSP00000453732}; Flags: Fragment;+++[H0YMX2_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 73 {ECO:0000313|Ensembl:ENSP00000453779}; Flags: Fragment;+++[Q5RKY8_HUMAN|Unreviewed]SubName: Full=WDR73 protein {ECO:0000313|EMBL:AAH50648.1}; Flags: Fragment;+++[Q6PJL8_HUMAN|Unreviewed]SubName: Full=WDR73 protein {ECO:0000313|EMBL:AAH14115.1}; Flags: Fragment;"]
[84958,"'SYTL1'",7,3,4,4.66666666666667,"05131///Shigellosis+++04810///Regulation of actin cytoskeleton+++04666///Fc gamma R-mediated phagocytosis+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++04520///Adherens junction+++05231///Choline metabolism in cancer",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0019897///extrinsic component of plasma membrane+++GO:0031528///microvillus membrane+++GO:0070382///exocytic vesicle+++GO:0005623///cell+++GO:0042470///melanosome+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0042043///neurexin family protein binding+++GO:0017137///Rab GTPase binding+++GO:0005515///protein binding","GO:0006887///exocytosis+++GO:0006886///intracellular protein transport","synaptotagmin like 1","[SYTL1_HUMAN|Reviewed]RecName: Full=Synaptotagmin-like protein 1; AltName: Full=Exophilin-7; AltName: Full=Protein JFC1;+++[A0A087X1N4_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-like protein 1 {ECO:0000313|Ensembl:ENSP00000484337};+++[Q5SSC6_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-like protein 1 {ECO:0000313|Ensembl:ENSP00000420110}; Flags: Fragment;"]
[84986,"'ARHGAP19'",67,66,62,65,{"$nulls":4},"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity","Rho GTPase activating protein 19","[RHG19_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 19; AltName: Full=Rho-type GTPase-activating protein 19;+++[A0A2X0U4I8_HUMAN|Unreviewed]SubName: Full=ARHGAP19 {ECO:0000313|EMBL:SPT35690.1}; Flags: Fragment;+++[R4GMS4_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 19 {ECO:0000313|Ensembl:ENSP00000473327}; Flags: Fragment;+++[R4GNI4_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 19 {ECO:0000313|Ensembl:ENSP00000473667}; Flags: Fragment;"]
[85013,"'TMEM128'",142,121,107,123.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005575///cellular_component+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0008150///biological_process","transmembrane protein 128","[TM128_HUMAN|Reviewed]RecName: Full=Transmembrane protein 128;+++[B7Z3K1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51973 {ECO:0000313|EMBL:BAH12237.1};"]
[8509,"'NDST2'",503,558,486,515.666666666667,"01100///Metabolic pathways+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",null,"M00059///Glycosaminoglycan biosynthesis, heparan sulfate backbone",null,"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0019213///deacetylase activity+++GO:0016787///hydrolase activity+++GO:0016740///transferase activity+++GO:0050119///N-acetylglucosamine deacetylase activity+++GO:0015016///[heparan sulfate]-glucosamine N-sulfotransferase activity+++GO:0008146///sulfotransferase activity+++GO:0003824///catalytic activity","GO:0030210///heparin biosynthetic process+++GO:0006790///sulfur compound metabolic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0008152///metabolic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0002002///regulation of angiotensin levels in blood","N-deacetylase and N-sulfotransferase 2","[NDST2_HUMAN|Reviewed]RecName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; EC=2.8.2.8; AltName: Full=Glucosaminyl N-deacetylase/N-sulfotransferase 2; Short=NDST-2; AltName: Full=N-heparan sulfate sulfotransferase 2; Short=N-HSST 2; Includes: RecName: Full=Heparan sulfate N-deacetylase 2; EC=3.-.-.-; Includes: RecName: Full=Heparan sulfate N-sulfotransferase 2; EC=2.8.2.-;+++[B4DE98_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[B4DU70_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[B4E139_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61027, highly similar to Bifunctional heparan sulfateN-deacetylase/N-sulfotransferase 2 {ECO:0000313|EMBL:BAG64651.1};+++[H7C032_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155}; Flags: Fragment;+++[S4R438_HUMAN|Unreviewed]SubName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 {ECO:0000313|Ensembl:ENSP00000475031};+++[V9GY34_HUMAN|Unreviewed]SubName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 {ECO:0000313|Ensembl:ENSP00000476336}; Flags: Fragment;"]
[85315,"'PAQR8'",93,126,99,106,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005496///steroid binding+++GO:0038023///signaling receptor activity+++GO:0008289///lipid binding","GO:0007275///multicellular organism development+++GO:0048477///oogenesis+++GO:0030154///cell differentiation","progestin and adipoQ receptor family member 8","[PAQR8_HUMAN|Reviewed]RecName: Full=Membrane progestin receptor beta {ECO:0000303|PubMed:23763432}; Short=mPR beta {ECO:0000303|PubMed:23763432}; AltName: Full=Lysosomal membrane protein in brain 1 {ECO:0000303|PubMed:11676489}; AltName: Full=Membrane progesterone P4 receptor beta {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone receptor beta {ECO:0000303|PubMed:23763432}; AltName: Full=Progesterone and adipoQ receptor family member 8; AltName: Full=Progestin and adipoQ receptor family member 8 {ECO:0000303|PubMed:16044242}; AltName: Full=Progestin and adipoQ receptor family member VIII;+++[A0A024RD52_HUMAN|Unreviewed]SubName: Full=Progestin and adipoQ receptor family member VIII, isoform CRA_a {ECO:0000313|EMBL:EAX04369.1};+++[B3KXW6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46206 fis, clone TESTI4010721, highly similar to Membrane progestin receptor beta {ECO:0000313|EMBL:BAG54628.1};+++[D6RCM7_HUMAN|Unreviewed]SubName: Full=Membrane progestin receptor beta {ECO:0000313|Ensembl:ENSP00000427161}; Flags: Fragment;+++[L8EBD2_HUMAN|Unreviewed]SubName: Full=Alternative protein PAQR8 {ECO:0000313|EMBL:CCQ43823.1};"]
[85360,"'SYDE1'",1654,1779,1594,1675.66666666667,{"$nulls":4},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:1901165///positive regulation of trophoblast cell migration+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0090630///activation of GTPase activity+++GO:0051493///regulation of cytoskeleton organization+++GO:0007165///signal transduction","synapse defective Rho GTPase homolog 1","[SYDE1_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein SYDE1; AltName: Full=Synapse defective protein 1 homolog 1; Short=Protein syd-1 homolog 1;+++[A0A2X0SFL9_HUMAN|Unreviewed]SubName: Full=SYDE1 {ECO:0000313|EMBL:SPT35803.1}; Flags: Fragment;+++[M0QXZ8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein SYDE1 {ECO:0000313|Ensembl:ENSP00000469489}; SubName: Full=Synapse defective 1, Rho GTPase, homolog 1 (C. elegans), isoform CRA_a {ECO:0000313|EMBL:EAW84461.1};+++[M0R101_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein SYDE1 {ECO:0000313|Ensembl:ENSP00000471553}; Flags: Fragment;+++[M0R3D3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein SYDE1 {ECO:0000313|Ensembl:ENSP00000473151}; Flags: Fragment;"]
[85415,"'RHPN2'",479.96,525,438,480.986666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm",null,"GO:0007165///signal transduction","rhophilin Rho GTPase binding protein 2","[RHPN2_HUMAN|Reviewed]RecName: Full=Rhophilin-2; AltName: Full=76 kDa RhoB effector protein; AltName: Full=GTP-Rho-binding protein 2; AltName: Full=p76RBE;+++[K7EL35_HUMAN|Unreviewed]SubName: Full=Rhophilin-2 {ECO:0000313|Ensembl:ENSP00000465898};"]
[85442,"'KNDC1'",197,213,155,188.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0043204///perikaryon+++GO:0030425///dendrite+++GO:0005575///cellular_component+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0043025///neuronal cell body","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0003674///molecular_function","GO:0050773///regulation of dendrite development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007264///small GTPase mediated signal transduction+++GO:0048814///regulation of dendrite morphogenesis+++GO:0021707///cerebellar granule cell differentiation+++GO:0008150///biological_process","kinase non-catalytic C-lobe domain containing 1","[KNDC1_HUMAN|Reviewed]RecName: Full=Kinase non-catalytic C-lobe domain-containing protein 1 {ECO:0000312|HGNC:HGNC:29374}; Short=KIND domain-containing protein 1 {ECO:0000303|PubMed:24788352}; AltName: Full=Cerebral protein 9 {ECO:0000303|Ref.1}; AltName: Full=Protein very KIND {ECO:0000250|UniProtKB:Q0KK55}; Short=v-KIND {ECO:0000250|UniProtKB:Q0KK55}; AltName: Full=Ras-GEF domain-containing family member 2 {ECO:0000312|HGNC:HGNC:29374};+++[Q5U5J6_HUMAN|Unreviewed]SubName: Full=KNDC1 protein {ECO:0000313|EMBL:AAH47924.1}; Flags: Fragment;"]
[85459,"'CEP295'",249,244,226,239.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:1990498///mitotic spindle microtubule+++GO:0005815///microtubule organizing center+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0005829///cytosol","GO:0008017///microtubule binding","GO:1903724///positive regulation of centriole elongation+++GO:0010825///positive regulation of centrosome duplication+++GO:1904951///positive regulation of establishment of protein localization+++GO:1901985///positive regulation of protein acetylation","centrosomal protein 295","[CE295_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 295 kDa {ECO:0000305};+++[E9PJG3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 295 kDa {ECO:0000313|Ensembl:ENSP00000431853}; Flags: Fragment;+++[E9PJY3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 295 kDa {ECO:0000313|Ensembl:ENSP00000433650}; Flags: Fragment;+++[E9PM20_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 295 kDa {ECO:0000313|Ensembl:ENSP00000433198}; Flags: Fragment;+++[H0YDK0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 295 kDa {ECO:0000313|Ensembl:ENSP00000433794}; Flags: Fragment;"]
[8562,"'DENR'",595.02,553.95,563.91,570.96,{"$nulls":4},"GO:0005575///cellular_component+++GO:0005840///ribosome","GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0003743///translation initiation factor activity+++GO:0003729///mRNA binding","GO:0002188///translation reinitiation+++GO:0075522///IRES-dependent viral translational initiation+++GO:0032790///ribosome disassembly+++GO:0006413///translational initiation+++GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation","density regulated re-initiation and release factor","[DENR_HUMAN|Reviewed]RecName: Full=Density-regulated protein; Short=DRP; AltName: Full=Protein DRP1; AltName: Full=Smooth muscle cell-associated protein 3; Short=SMAP-3;+++[A0A024RBR3_HUMAN|Unreviewed]RecName: Full=Density-regulated protein {ECO:0000256|RuleBase:RU361273};+++[F8VVL1_HUMAN|Unreviewed]RecName: Full=Density-regulated protein {ECO:0000256|RuleBase:RU361273};+++[L8E7I3_HUMAN|Unreviewed]SubName: Full=Alternative protein DENR {ECO:0000313|EMBL:CCQ43230.1};"]
[857,"'CAV1'",547,335,405,429,"04144///Endocytosis+++04510///Focal adhesion+++05416///Viral myocarditis+++05205///Proteoglycans in cancer+++05100///Bacterial invasion of epithelial cells+++05418///Fluid shear stress and atherosclerosis","H00419///Congenital generalized lipodystrophy (CGL)+++H01621///Pulmonary arterial hypertension (PAH)",null,null,"GO:0005938///cell cortex+++GO:0042383///sarcolemma+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0002080///acrosomal membrane+++GO:0016021///integral component of membrane+++GO:0030666///endocytic vesicle membrane+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0005794///Golgi apparatus+++GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0016324///apical plasma membrane+++GO:0005901///caveola+++GO:0045121///membrane raft+++GO:0005929///cilium","GO:0030674///protein binding, bridging+++GO:0005198///structural molecule activity+++GO:0070320///inward rectifier potassium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0015485///cholesterol binding+++GO:0048365///Rac GTPase binding+++GO:0051117///ATPase binding+++GO:0005113///patched binding+++GO:0044325///ion channel binding+++GO:0046982///protein heterodimerization activity+++GO:0016504///peptidase activator activity+++GO:0019899///enzyme binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0050998///nitric-oxide synthase binding+++GO:0042802///identical protein binding","GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:1903598///positive regulation of gap junction assembly+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0006874///cellular calcium ion homeostasis+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0006641///triglyceride metabolic process+++GO:0031295///T cell costimulation+++GO:0019217///regulation of fatty acid metabolic process+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0050900///leukocyte migration+++GO:0016050///vesicle organization+++GO:0042632///cholesterol homeostasis+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0051259///protein complex oligomerization+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:0002931///response to ischemia+++GO:0030193///regulation of blood coagulation+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0009968///negative regulation of signal transduction+++GO:1903609///negative regulation of inward rectifier potassium channel activity+++GO:0032092///positive regulation of protein binding+++GO:0031398///positive regulation of protein ubiquitination+++GO:0032570///response to progesterone+++GO:0051260///protein homooligomerization+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0007595///lactation+++GO:0030879///mammary gland development+++GO:0042310///vasoconstriction+++GO:0043409///negative regulation of MAPK cascade+++GO:0086098///angiotensin-activated signaling pathway involved in heart process+++GO:0010952///positive regulation of peptidase activity+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0030154///cell differentiation+++GO:0001525///angiogenesis+++GO:0051899///membrane depolarization+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0043627///response to estrogen+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0032091///negative regulation of protein binding+++GO:2000286///receptor internalization involved in canonical Wnt signaling pathway+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0006816///calcium ion transport+++GO:0007519///skeletal muscle tissue development+++GO:0032507///maintenance of protein location in cell+++GO:1904886///beta-catenin destruction complex disassembly+++GO:0070836///caveola assembly+++GO:0072584///caveolin-mediated endocytosis+++GO:0000188///inactivation of MAPK activity+++GO:0030301///cholesterol transport+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0010524///positive regulation of calcium ion transport into cytosol+++GO:0098903///regulation of membrane repolarization during action potential+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0019915///lipid storage+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0001570///vasculogenesis+++GO:0010608///posttranscriptional regulation of gene expression+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:0006940///regulation of smooth muscle contraction+++GO:0043085///positive regulation of catalytic activity+++GO:0031623///receptor internalization+++GO:0008104///protein localization+++GO:0033484///nitric oxide homeostasis+++GO:0003057///regulation of the force of heart contraction by chemical signal+++GO:0010628///positive regulation of gene expression+++GO:0008285///negative regulation of cell proliferation+++GO:2000535///regulation of entry of bacterium into host cell+++GO:0071455///cellular response to hyperoxia+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0051592///response to calcium ion+++GO:0043407///negative regulation of MAP kinase activity+++GO:0009617///response to bacterium+++GO:2000811///negative regulation of anoikis+++GO:1903361///protein localization to basolateral plasma membrane+++GO:0097190///apoptotic signaling pathway+++GO:0052547///regulation of peptidase activity+++GO:0030335///positive regulation of cell migration+++GO:0001666///response to hypoxia+++GO:0060056///mammary gland involution+++GO:0002026///regulation of the force of heart contraction+++GO:0044860///protein localization to plasma membrane raft+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1900085///negative regulation of peptidyl-tyrosine autophosphorylation+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0016032///viral process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0071360///cellular response to exogenous dsRNA+++GO:1900027///regulation of ruffle assembly+++GO:0048550///negative regulation of pinocytosis+++GO:0045907///positive regulation of vasoconstriction+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0055074///calcium ion homeostasis+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0009267///cellular response to starvation+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:0060546///negative regulation of necroptotic process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway","caveolin 1","[CAV1_HUMAN|Reviewed]RecName: Full=Caveolin-1;+++[A0A024R757_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};+++[A9XTE5_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680}; Flags: Fragment;+++[C9JKI3_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680}; Flags: Fragment;+++[E9PCT5_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};+++[F8WDM7_HUMAN|Unreviewed]SubName: Full=Caveolin-1 {ECO:0000313|Ensembl:ENSP00000409541};+++[L8EC89_HUMAN|Unreviewed]SubName: Full=Alternative protein CAV1 {ECO:0000313|EMBL:CCQ43147.1};+++[Q2TNI1_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};+++[Q59E85_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680}; Flags: Fragment;+++[Q7Z4F3_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};"]
[858,"'CAV2'",727,605,637.73,656.576666666667,"05418///Fluid shear stress and atherosclerosis+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++05205///Proteoglycans in cancer+++04510///Focal adhesion",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0002080///acrosomal membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005634///nucleus+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005901///caveola+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0042383///sarcolemma+++GO:0000139///Golgi membrane+++GO:0045121///membrane raft+++GO:0030133///transport vesicle","GO:0042803///protein homodimerization activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0019901///protein kinase binding+++GO:0030674///protein binding, bridging+++GO:0097110///scaffold protein binding+++GO:0031748///D1 dopamine receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0005198///structural molecule activity+++GO:0005515///protein binding","GO:0051259///protein complex oligomerization+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0006906///vesicle fusion+++GO:0030154///cell differentiation+++GO:0007005///mitochondrion organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0008285///negative regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:0060161///positive regulation of dopamine receptor signaling pathway+++GO:0007029///endoplasmic reticulum organization+++GO:0044794///positive regulation by host of viral process+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0016050///vesicle organization+++GO:0048741///skeletal muscle fiber development+++GO:0008286///insulin receptor signaling pathway+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0019065///receptor-mediated endocytosis of virus by host cell+++GO:0044791///positive regulation by host of viral release from host cell+++GO:0043547///positive regulation of GTPase activity+++GO:0048278///vesicle docking+++GO:0070836///caveola assembly","caveolin 2","[CAV2_HUMAN|Reviewed]RecName: Full=Caveolin-2;+++[E9PCT3_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};+++[Q53X57_HUMAN|Unreviewed]RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680}; Flags: Fragment;"]
[8621,"'CDK13'",935,950,802,895.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0002945///cyclin K-CDK13 complex+++GO:0005615///extracellular space+++GO:0000790///nuclear chromatin+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005576///extracellular region+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0019908///nuclear cyclin-dependent protein kinase holoenzyme complex","GO:0019901///protein kinase binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0003723///RNA binding+++GO:0030332///cyclin binding+++GO:0016301///kinase activity+++GO:0008134///transcription factor binding+++GO:0004672///protein kinase activity","GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0016032///viral process+++GO:0016310///phosphorylation+++GO:0008380///RNA splicing+++GO:0043312///neutrophil degranulation+++GO:0051301///cell division+++GO:0006468///protein phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0007275///multicellular organism development+++GO:0030097///hemopoiesis+++GO:0006397///mRNA processing+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:2000737///negative regulation of stem cell differentiation+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0007088///regulation of mitotic nuclear division+++GO:0008284///positive regulation of cell proliferation","cyclin dependent kinase 13","[CDK13_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 13; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=CDC2-related protein kinase 5; AltName: Full=Cell division cycle 2-like protein kinase 5; AltName: Full=Cell division protein kinase 13; Short=hCDK13; AltName: Full=Cholinesterase-related cell division controller;+++[A0A024RA66_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2-like 5 (Cholinesterase-related cell division controller), isoform CRA_b {ECO:0000313|EMBL:EAW94131.1};+++[A0A024RA85_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2-like 5 (Cholinesterase-related cell division controller), isoform CRA_a {ECO:0000313|EMBL:EAW94129.1};+++[A0A087X209_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000484610};+++[A0A2R8Y4Z0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000494168}; Flags: Fragment;+++[A0A2R8Y644_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000495036}; Flags: Fragment;+++[A0A2R8Y7W5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000496440}; Flags: Fragment;+++[A0A2R8Y7Y0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000496618}; Flags: Fragment;+++[A0A2R8YCQ1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000493853}; Flags: Fragment;+++[A0A2R8YD28_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000494206}; Flags: Fragment;+++[A0A2R8YEB7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000494207}; Flags: Fragment;+++[A0A2R8YF61_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000496187}; Flags: Fragment;+++[A0A2R8YFE7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000495083}; Flags: Fragment;+++[Q9BVE2_HUMAN|Unreviewed]SubName: Full=CDC2L5 protein {ECO:0000313|EMBL:AAH01274.1}; SubName: Full=Cyclin-dependent kinase 13 {ECO:0000313|Ensembl:ENSP00000480835};"]
[8638,"'OASL'",0,1,0,0.333333333333333,"05165///Human papillomavirus infection",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0003725///double-stranded RNA binding+++GO:0046966///thyroid hormone receptor binding+++GO:0001730///2'-5'-oligoadenylate synthetase activity+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding","GO:0060337///type I interferon signaling pathway+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0009615///response to virus+++GO:0045087///innate immune response+++GO:0060700///regulation of ribonuclease activity+++GO:0002376///immune system process+++GO:0051607///defense response to virus+++GO:0006955///immune response+++GO:0045071///negative regulation of viral genome replication","2'-5'-oligoadenylate synthetase like","[OASL_HUMAN|Reviewed]RecName: Full=2'-5'-oligoadenylate synthase-like protein; AltName: Full=2'-5'-OAS-related protein; Short=2'-5'-OAS-RP; AltName: Full=59 kDa 2'-5'-oligoadenylate synthase-like protein; AltName: Full=Thyroid receptor-interacting protein 14; Short=TR-interacting protein 14; Short=TRIP-14; AltName: Full=p59 OASL; Short=p59OASL;+++[H0YGP3_HUMAN|Unreviewed]SubName: Full=2'-5'-oligoadenylate synthase-like protein {ECO:0000313|Ensembl:ENSP00000444127}; Flags: Fragment;"]
[865,"'CBFB'",143,112,114,123,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016513///core-binding factor complex","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0060216///definitive hemopoiesis+++GO:0050855///regulation of B cell receptor signaling pathway+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030099///myeloid cell differentiation+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0048469///cell maturation+++GO:0030111///regulation of Wnt signaling pathway+++GO:0045616///regulation of keratinocyte differentiation+++GO:0001649///osteoblast differentiation+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0045637///regulation of myeloid cell differentiation+++GO:0030098///lymphocyte differentiation+++GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0000209///protein polyubiquitination+++GO:2000810///regulation of bicellular tight junction assembly+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0001503///ossification+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter","core-binding factor subunit beta","[PEBB_HUMAN|Reviewed]RecName: Full=Core-binding factor subunit beta; Short=CBF-beta; AltName: Full=Polyomavirus enhancer-binding protein 2 beta subunit; Short=PEA2-beta; Short=PEBP2-beta; AltName: Full=SL3-3 enhancer factor 1 subunit beta; AltName: Full=SL3/AKV core-binding factor beta subunit;+++[A0A024R6W3_HUMAN|Unreviewed]SubName: Full=Core-binding factor, beta subunit, isoform CRA_a {ECO:0000313|EMBL:EAW83071.1};+++[A0A024R6X2_HUMAN|Unreviewed]SubName: Full=Core-binding factor, beta subunit, isoform CRA_b {ECO:0000313|EMBL:EAW83069.1};+++[H3BSC0_HUMAN|Unreviewed]SubName: Full=Core-binding factor subunit beta {ECO:0000313|Ensembl:ENSP00000456637}; Flags: Fragment;+++[J3KRT0_HUMAN|Unreviewed]SubName: Full=Core-binding factor subunit beta {ECO:0000313|Ensembl:ENSP00000462148}; Flags: Fragment;+++[J3KS23_HUMAN|Unreviewed]SubName: Full=Core-binding factor subunit beta {ECO:0000313|Ensembl:ENSP00000462273};+++[J3KTD8_HUMAN|Unreviewed]SubName: Full=Core-binding factor subunit beta {ECO:0000313|Ensembl:ENSP00000462932}; Flags: Fragment;"]
[8672,"'EIF4G3'",2866,3392,3085,3114.33333333333,"03013///RNA transport+++05416///Viral myocarditis","H00057///Parkinson's disease (PD)","M00428///eIF4F complex",null,"GO:0005829///cytosol+++GO:0016281///eukaryotic translation initiation factor 4F complex","GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding","GO:0006412///translation+++GO:0006417///regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0010507///negative regulation of autophagy+++GO:0006413///translational initiation","eukaryotic translation initiation factor 4 gamma 3","[IF4G3_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 4 gamma 3; Short=eIF-4-gamma 3; Short=eIF-4G 3; Short=eIF4G 3; AltName: Full=eIF-4-gamma II; Short=eIF4GII;+++[A0A0A0MSA7_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0000313|Ensembl:ENSP00000383274};+++[A0A0U1RQK7_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0000313|Ensembl:ENSP00000489051};+++[B1AN91_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0000313|Ensembl:ENSP00000395381}; Flags: Fragment;+++[B1AN92_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0000313|Ensembl:ENSP00000396083}; Flags: Fragment;+++[Q59GJ0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 4 gamma, 3 variant {ECO:0000313|EMBL:BAD92356.1}; Flags: Fragment;"]
[8690,"'JRKL'",90,98,108,98.6666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0007417///central nervous system development","JRK like","[JERKL_HUMAN|Reviewed]RecName: Full=Jerky protein homolog-like; AltName: Full=Human homolog of mouse jerky gene protein; Short=HHMJG;"]
[8717,"'TRADD'",188,249,176,204.333333333333,"04920///Adipocytokine signaling pathway+++04210///Apoptosis+++04071///Sphingolipid signaling pathway+++05169///Epstein-Barr virus infection+++04217///Necroptosis+++05203///Viral carcinogenesis+++05163///Human cytomegalovirus infection+++04064///NF-kappa B signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04622///RIG-I-like receptor signaling pathway+++04657///IL-17 signaling pathway+++05160///Hepatitis C+++05152///Tuberculosis+++04010///MAPK signaling pathway+++04668///TNF signaling pathway+++05165///Human papillomavirus infection",{"$nulls":3},"GO:0045121///membrane raft+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031264///death-inducing signaling complex+++GO:0043235///receptor complex","GO:0042802///identical protein binding+++GO:0019900///kinase binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0060090///molecular adaptor activity+++GO:0070513///death domain binding","GO:0097191///extrinsic apoptotic signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0071550///death-inducing signaling complex assembly+++GO:0007165///signal transduction+++GO:0051798///positive regulation of hair follicle development+++GO:0050729///positive regulation of inflammatory response+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0071356///cellular response to tumor necrosis factor+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0051291///protein heterooligomerization+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0006915///apoptotic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0030335///positive regulation of cell migration+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling","TNFRSF1A associated via death domain","[TRADD_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor receptor type 1-associated DEATH domain protein; Short=TNFR1-associated DEATH domain protein; AltName: Full=TNFRSF1A-associated via death domain;"]
[8732,"'RNGTT'",236,221,205,220.666666666667,"03015///mRNA surveillance pathway",null,null,"R10814///5'-triphospho-[mRNA] phosphohydrolase   5'-Triphospho-[mRNA] + H2O <=> (5')ppPur-mRNA + Orthophosphate+++R03828///GTP:mRNA guanylyltransferase   GTP + (5')ppPur-mRNA <=> Diphosphate + G(5')pppPur-mRNA","GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0004651///polynucleotide 5'-phosphatase activity+++GO:0005525///GTP binding+++GO:0050355///triphosphatase activity+++GO:0016791///phosphatase activity+++GO:0004484///mRNA guanylyltransferase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016740///transferase activity+++GO:0008192///RNA guanylyltransferase activity+++GO:0016787///hydrolase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0000166///nucleotide binding","GO:0006370///7-methylguanosine mRNA capping+++GO:0098507///polynucleotide 5' dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006396///RNA processing+++GO:0006366///transcription by RNA polymerase II+++GO:0008152///metabolic process+++GO:0016032///viral process+++GO:0006397///mRNA processing+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation","RNA guanylyltransferase and 5'-phosphatase","[MCE1_HUMAN|Reviewed]RecName: Full=mRNA-capping enzyme; AltName: Full=HCAP1; AltName: Full=HCE; Includes: RecName: Full=Polynucleotide 5'-triphosphatase; EC=3.1.3.33; AltName: Full=mRNA 5'-triphosphatase; Short=TPase; Includes: RecName: Full=mRNA guanylyltransferase; EC=2.7.7.50; AltName: Full=GTP--RNA guanylyltransferase; Short=GTase;+++[B4DSJ8_HUMAN|Unreviewed]RecName: Full=mRNA-capping enzyme {ECO:0000256|PIRNR:PIRNR036958}; Includes: RecName: Full=Polynucleotide 5'-triphosphatase {ECO:0000256|PIRNR:PIRNR036958}; EC=3.1.3.33 {ECO:0000256|PIRNR:PIRNR036958}; Includes: RecName: Full=mRNA guanylyltransferase {ECO:0000256|PIRNR:PIRNR036958}; EC=2.7.7.50 {ECO:0000256|PIRNR:PIRNR036958}; AltName: Full=GTP--RNA guanylyltransferase {ECO:0000256|PIRNR:PIRNR036958}; Short=GTase {ECO:0000256|PIRNR:PIRNR036958};+++[Q7Z3R6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686J2031 {ECO:0000313|EMBL:CAD97693.1}; Flags: Fragment;"]
[8749,"'ADAM18'",2,0,1,1,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity","GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation","ADAM metallopeptidase domain 18","[ADA18_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 18; Short=ADAM 18; AltName: Full=Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; Short=tMDC III; Flags: Precursor;+++[E5RIP0_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000429335};+++[E5RK96_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000428083};+++[Q0VAI3_HUMAN|Unreviewed]SubName: Full=ADAM18 protein {ECO:0000313|EMBL:AAI21047.1};"]
[8778,"'SIGLEC5'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0030667///secretory granule membrane+++GO:0070821///tertiary granule membrane+++GO:0101003///ficolin-1-rich granule membrane","GO:0030246///carbohydrate binding+++GO:0005515///protein binding","GO:0007155///cell adhesion+++GO:0043312///neutrophil degranulation","sialic acid binding Ig like lectin 5","[SIGL5_HUMAN|Reviewed]RecName: Full=Sialic acid-binding Ig-like lectin 5; Short=Siglec-5; AltName: Full=CD33 antigen-like 2; AltName: Full=Obesity-binding protein 2; Short=OB-BP2; Short=OB-binding protein 2; AltName: CD_antigen=CD170; Flags: Precursor;"]
[8798,"'DYRK4'",290,352,290,310.666666666667,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity","GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","dual specificity tyrosine phosphorylation regulated kinase 4","[DYRK4_HUMAN|Reviewed]RecName: Full=Dual specificity tyrosine-phosphorylation-regulated kinase 4; EC=2.7.12.1;+++[A0A0A0MTH5_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 4 {ECO:0000313|Ensembl:ENSP00000439697};+++[B4E1A4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61032, highly similar to Dual specific itytyrosine-phosphorylation-regulated kinase 4 {ECO:0000313|EMBL:BAG64716.1};+++[D3JEN0_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 {ECO:0000313|EMBL:ADC33153.1}; Flags: Fragment;+++[D3JEN1_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 {ECO:0000313|EMBL:ADC33154.1}; Flags: Fragment;+++[D3JEN2_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 {ECO:0000313|EMBL:ADC33155.1}; Flags: Fragment;+++[D3JEN3_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 {ECO:0000313|EMBL:ADC33156.1}; Flags: Fragment;+++[D3JEN4_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 {ECO:0000313|EMBL:ADC33157.1}; Flags: Fragment;+++[F5GWS4_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 4 {ECO:0000313|Ensembl:ENSP00000441996};+++[F5H3D3_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 4 {ECO:0000313|Ensembl:ENSP00000439168};+++[F5H4X6_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 4 {ECO:0000313|Ensembl:ENSP00000444842};+++[H0YFI4_HUMAN|Unreviewed]SubName: Full=Dual-specificity tyrosine-phosphorylation-regulated kinase 4 {ECO:0000313|Ensembl:ENSP00000438769}; Flags: Fragment;"]
[8817,"'FGF18'",194,183,194,190.333333333333,"04010///MAPK signaling pathway+++05200///Pathways in cancer+++05226///Gastric cancer+++04015///Rap1 signaling pathway+++04810///Regulation of actin cytoskeleton+++04014///Ras signaling pathway+++05218///Melanoma+++04151///PI3K-Akt signaling pathway+++05224///Breast cancer","H01905///Trichomegaly+++H00677///Aplasia of lacrimal and salivary glands+++H00041///Kaposi's sarcoma+++H00642///Lacrimo-auriculo-dento-digital syndrome (LADD)+++H01728///Potter syndrome+++H01854///Metacarpal 4-5 fusion (MF4)+++H00605///Deafness, autosomal recessive+++H00255///Hypogonadotropic hypogonadism+++H00484///Other brachydactylies",null,null,"GO:0005730///nucleolus+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0005104///fibroblast growth factor receptor binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0008083///growth factor activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0005111///type 2 fibroblast growth factor receptor binding","GO:0008284///positive regulation of cell proliferation+++GO:0030324///lung development+++GO:0045766///positive regulation of angiogenesis+++GO:0010469///regulation of signaling receptor activity+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0007165///signal transduction+++GO:0043406///positive regulation of MAP kinase activity+++GO:0001503///ossification+++GO:0009653///anatomical structure morphogenesis+++GO:0002063///chondrocyte development+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0001525///angiogenesis+++GO:2000546///positive regulation of endothelial cell chemotaxis to fibroblast growth factor+++GO:1903670///regulation of sprouting angiogenesis+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0001958///endochondral ossification+++GO:0001957///intramembranous ossification+++GO:0007267///cell-cell signaling+++GO:0000165///MAPK cascade+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0001936///regulation of endothelial cell proliferation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0051897///positive regulation of protein kinase B signaling","fibroblast growth factor 18","[FGF18_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor 18; Short=FGF-18; AltName: Full=zFGF5; Flags: Precursor;"]
[8833,"'GMPS'",694.91,599,645.34,646.416666666667,"00230///Purine metabolism+++00983///Drug metabolism - other enzymes+++01100///Metabolic pathways",null,"M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP","R01230///Xanthosine-5'-phosphate:ammonia ligase (AMP-forming)   ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMP+++R08244///6-thioxanthine 5'-monophosphate:L-glutamine amido-ligase (AMP-forming)   6-Thioxanthine 5'-monophosphate + ATP + L-Glutamine + H2O <=> 6-Thioguanosine monophosphate + AMP + Diphosphate + L-Glutamate+++R01231///Xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)   ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-Glutamate","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0003921///GMP synthase activity+++GO:0003922///GMP synthase (glutamine-hydrolyzing) activity+++GO:0016874///ligase activity+++GO:0016462///pyrophosphatase activity","GO:0006177///GMP biosynthetic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0006541///glutamine metabolic process","guanine monophosphate synthase","[GUAA_HUMAN|Reviewed]RecName: Full=GMP synthase [glutamine-hydrolyzing]; EC=6.3.5.2; AltName: Full=GMP synthetase; AltName: Full=Glutamine amidotransferase;+++[A0A140VJK6_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 82 {ECO:0000313|EMBL:AEE60993.1};"]
[8853,"'ASAP2'",753,730,763,748.666666666667,"04666///Fc gamma R-mediated phagocytosis+++04144///Endocytosis",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0032580///Golgi cisterna membrane","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity","ArfGAP with SH3 domain, ankyrin repeat and PH domain 2","[ASAP2_HUMAN|Reviewed]RecName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; AltName: Full=Development and differentiation-enhancing factor 2; AltName: Full=Paxillin-associated protein with ARF GAP activity 3; Short=PAG3; AltName: Full=Pyk2 C-terminus-associated protein; Short=PAP;+++[A0A286YFG8_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000493293}; Flags: Fragment;+++[Q53R39_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DDEF2 {ECO:0000313|EMBL:AAY24112.1}; Flags: Fragment;+++[Q53RS3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DDEF2 {ECO:0000313|EMBL:AAY14856.1}; Flags: Fragment;+++[Q53RT9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DDEF2 {ECO:0000313|EMBL:AAY14904.1}; Flags: Fragment;"]
[8872,"'CDC123'",835,718,742,765,{"$nulls":4},"GO:0005737///cytoplasm",null,"GO:0008284///positive regulation of cell proliferation+++GO:0045948///positive regulation of translational initiation+++GO:0051301///cell division+++GO:0007050///cell cycle arrest+++GO:1905143///eukaryotic translation initiation factor 2 complex assembly+++GO:0007049///cell cycle","cell division cycle 123","[CD123_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 123 homolog; Short=Protein D123; AltName: Full=HT-1080; AltName: Full=PZ32;+++[H7BZW7_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 123 homolog {ECO:0000313|Ensembl:ENSP00000391851}; Flags: Fragment;+++[X6RA30_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 123 homolog {ECO:0000313|Ensembl:ENSP00000368178};+++[X6RF82_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 123 homolog {ECO:0000313|Ensembl:ENSP00000398724}; Flags: Fragment;+++[X6RKY7_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 123 homolog {ECO:0000313|Ensembl:ENSP00000415806}; Flags: Fragment;"]
[8893,"'EIF2B5'",500,671,565,578.666666666667,"03013///RNA transport","H00869///Leukoencephalopathy with vanishing white matter",null,null,"GO:0005851///eukaryotic translation initiation factor 2B complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003743///translation initiation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031369///translation initiation factor binding","GO:0045948///positive regulation of translational initiation+++GO:0048708///astrocyte differentiation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0009408///response to heat+++GO:0010226///response to lithium ion+++GO:0007568///aging+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0001541///ovarian follicle development+++GO:0042552///myelination+++GO:0014002///astrocyte development+++GO:0050852///T cell receptor signaling pathway+++GO:0009749///response to glucose+++GO:0043434///response to peptide hormone+++GO:0021766///hippocampus development+++GO:0043065///positive regulation of apoptotic process+++GO:0045727///positive regulation of translation+++GO:0014003///oligodendrocyte development","eukaryotic translation initiation factor 2B subunit epsilon","[EI2BE_HUMAN|Reviewed]RecName: Full=Translation initiation factor eIF-2B subunit epsilon; AltName: Full=eIF-2B GDP-GTP exchange factor subunit epsilon;+++[C9JRD9_HUMAN|Unreviewed]SubName: Full=Translation initiation factor eIF-2B subunit epsilon {ECO:0000313|Ensembl:ENSP00000414775};+++[H7C2X0_HUMAN|Unreviewed]SubName: Full=Translation initiation factor eIF-2B subunit epsilon {ECO:0000313|Ensembl:ENSP00000408198}; Flags: Fragment;"]
[8908,"'GYG2'",485,489,458,477.333333333333,"01100///Metabolic pathways+++00500///Starch and sucrose metabolism","H01762///Muscle glycogen storage disease+++H01955///Glycogen storage disease type XV+++H00069///Glycogen storage diseases (GSD)",null,"R03681///UDP-alpha-D-glucose:glycogenin alpha-D-glucosyltransferase   UDP-glucose + Glycogenin <=> UDP + alpha-D-Glucosylglycogenin+++R00292///UDP-glucose:glycogen 4-alpha-D-glucosyltransferase   UDP-glucose + Amylose <=> UDP + Amylose","GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0102751///UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008466///glycogenin glucosyltransferase activity","GO:0005978///glycogen biosynthetic process","glycogenin 2","[GLYG2_HUMAN|Reviewed]RecName: Full=Glycogenin-2; Short=GN-2; Short=GN2; EC=2.4.1.186;+++[A0A1W2PQ75_HUMAN|Unreviewed]SubName: Full=Glycogenin-2 {ECO:0000313|Ensembl:ENSP00000491962};+++[B3KUV6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40727 fis, clone TKIDN2000127, highly similar to Glycogenin-2 {ECO:0000313|EMBL:BAG53568.1};+++[E5RIC9_HUMAN|Unreviewed]SubName: Full=Glycogenin-2 {ECO:0000313|Ensembl:ENSP00000430764}; Flags: Fragment;+++[J3QSZ3_HUMAN|Unreviewed]SubName: Full=Glycogenin-2 {ECO:0000313|Ensembl:ENSP00000370549}; Flags: Fragment;+++[Q1ZYL7_HUMAN|Unreviewed]SubName: Full=Glycogenin 2 {ECO:0000313|EMBL:ABD83666.1};"]
[8927,"'BSN'",96,106,88,96.6666666666667,{"$nulls":4},"GO:0044306///neuron projection terminus+++GO:0009986///cell surface+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0098978///glutamatergic synapse+++GO:0043005///neuron projection+++GO:0060076///excitatory synapse+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0005856///cytoskeleton+++GO:0030424///axon+++GO:0048786///presynaptic active zone+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0008021///synaptic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0014069///postsynaptic density+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0098793///presynapse+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0098982///GABA-ergic synapse+++GO:0005737///cytoplasm+++GO:0030672///synaptic vesicle membrane","GO:0046872///metal ion binding+++GO:0098882///structural constituent of presynaptic active zone","GO:0099526///presynapse to nucleus signaling pathway+++GO:0007416///synapse assembly+++GO:0007268///chemical synaptic transmission+++GO:0035418///protein localization to synapse+++GO:0048790///maintenance of presynaptic active zone structure+++GO:0098693///regulation of synaptic vesicle cycle","bassoon presynaptic cytomatrix protein","[BSN_HUMAN|Reviewed]RecName: Full=Protein bassoon {ECO:0000305}; AltName: Full=Zinc finger protein 231;+++[A0A024R2Y4_HUMAN|Unreviewed]SubName: Full=Bassoon (Presynaptic cytomatrix protein), isoform CRA_a {ECO:0000313|EMBL:EAW64993.1};"]
[8933,"'RTL8C'",5792,5135,4960,5295.66666666667,{"$nulls":4},"GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0008150///biological_process","retrotransposon Gag like 8C","[CXX1_HUMAN|Reviewed]RecName: Full=CAAX box protein 1; AltName: Full=Cerebral protein 5; Flags: Precursor;+++[RTL8C_HUMAN|Reviewed]RecName: Full=Retrotransposon Gag-like protein 8B {ECO:0000312|HGNC:HGNC:2569}; AltName: Full=Mammalian retrotransposon derived protein 8C {ECO:0000312|HGNC:HGNC:2569};"]
[89801,"'PPP1R3F'",140,176,143,153,"04910///Insulin signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:2001069///glycogen binding+++GO:0019903///protein phosphatase binding","GO:0005979///regulation of glycogen biosynthetic process+++GO:2000465///regulation of glycogen (starch) synthase activity","protein phosphatase 1 regulatory subunit 3F","[PPR3F_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1 regulatory subunit 3F; Short=R3F;+++[H7C546_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1 regulatory subunit 3F {ECO:0000313|Ensembl:ENSP00000418949}; Flags: Fragment;+++[Q0D2I0_HUMAN|Unreviewed]SubName: Full=PPP1R3F protein {ECO:0000313|EMBL:AAI10406.1}; Flags: Fragment;"]
[89848,"'FCHSD1'",416,399,440,418.333333333333,{"$nulls":4},"GO:0055037///recycling endosome+++GO:0031594///neuromuscular junction",null,"GO:0030833///regulation of actin filament polymerization+++GO:0007274///neuromuscular synaptic transmission","FCH and double SH3 domains 1","[FCSD1_HUMAN|Reviewed]RecName: Full=F-BAR and double SH3 domains protein 1;+++[E5RGB1_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 1 {ECO:0000313|Ensembl:ENSP00000428776};+++[E5RGT6_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 1 {ECO:0000313|Ensembl:ENSP00000428677};+++[E5RK49_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 1 {ECO:0000313|Ensembl:ENSP00000430448}; Flags: Fragment;"]
[89886,"'SLAMF9'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process","SLAM family member 9","[SLAF9_HUMAN|Reviewed]RecName: Full=SLAM family member 9; AltName: Full=CD2 family member 10; Short=CD2F-10; AltName: Full=CD84 homolog 1; Short=CD84-H1; Flags: Precursor;+++[Q6NSE6_HUMAN|Unreviewed]SubName: Full=SLAMF9 protein {ECO:0000313|EMBL:AAH70213.1};"]
[8995,"'TNFSF18'",1,0,0,0.333333333333333,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0042802///identical protein binding+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0032813///tumor necrosis factor receptor superfamily binding+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0045785///positive regulation of cell adhesion+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0042129///regulation of T cell proliferation+++GO:0002250///adaptive immune response+++GO:0002687///positive regulation of leukocyte migration+++GO:0010469///regulation of signaling receptor activity+++GO:0007267///cell-cell signaling+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0002376///immune system process+++GO:0002309///T cell proliferation involved in immune response","TNF superfamily member 18","[TNF18_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 18; AltName: Full=Activation-inducible TNF-related ligand; Short=AITRL; AltName: Full=Glucocorticoid-induced TNF-related ligand; Short=hGITRL;+++[A0A0U5JXL4_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 2A {ECO:0000313|EMBL:CTQ86083.1};"]
[9013,"'TAF1C'",955,1314,1346,1205,{"$nulls":4},"GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006366///transcription by RNA polymerase II+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0006363///termination of RNA polymerase I transcription+++GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006356///regulation of transcription by RNA polymerase I+++GO:0006360///transcription by RNA polymerase I","TATA-box binding protein associated factor, RNA polymerase I subunit C","[TAF1C_HUMAN|Reviewed]RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C; AltName: Full=RNA polymerase I-specific TBP-associated factor 110 kDa; Short=TAFI110; AltName: Full=TATA box-binding protein-associated factor 1C; Short=TBP-associated factor 1C; AltName: Full=Transcription initiation factor SL1/TIF-IB subunit C;+++[B3KUE8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39712 fis, clone SMINT2013129, highly similar to TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|EMBL:BAG53410.1};+++[H3BMQ4_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000454494};+++[H3BNH3_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000454854}; Flags: Fragment;+++[H3BQH8_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000455787};+++[H3BQZ8_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000456011}; Flags: Fragment;+++[H3BR71_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000456101}; Flags: Fragment;+++[H3BR91_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000456133};+++[H3BTQ6_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000457281};+++[H3BUZ7_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit C {ECO:0000313|Ensembl:ENSP00000457883}; Flags: Fragment;"]
[90187,"'EMILIN3'",253,340,303,298.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0031012///extracellular matrix","GO:0005201///extracellular matrix structural constituent",null,"elastin microfibril interfacer 3","[EMIL3_HUMAN|Reviewed]RecName: Full=EMILIN-3; AltName: Full=EMILIN-5; AltName: Full=Elastin microfibril interface-located protein 3; Short=Elastin microfibril interfacer 3; AltName: Full=Elastin microfibril interface-located protein 5; Short=Elastin microfibril interfacer 5; Flags: Precursor;"]
[90313,"'TP53I13'",1035,1173,979,1062.33333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0045786///negative regulation of cell cycle+++GO:0009411///response to UV+++GO:0014070///response to organic cyclic compound+++GO:0042493///response to drug","tumor protein p53 inducible protein 13","[P5I13_HUMAN|Reviewed]RecName: Full=Tumor protein p53-inducible protein 13; AltName: Full=Damage-stimulated cytoplasmic protein 1; Flags: Precursor;+++[A0A024QZ67_HUMAN|Unreviewed]SubName: Full=Tumor protein p53 inducible protein 13, isoform CRA_b {ECO:0000313|EMBL:EAW51194.1};+++[H0Y3E9_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 13 {ECO:0000313|Ensembl:ENSP00000368095}; Flags: Fragment;+++[J3KRJ1_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 13 {ECO:0000313|Ensembl:ENSP00000462026}; Flags: Fragment;+++[J3KSX2_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 13 {ECO:0000313|Ensembl:ENSP00000462693}; Flags: Fragment;+++[K7EJC6_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 13 {ECO:0000313|Ensembl:ENSP00000465112}; Flags: Fragment;+++[K7EKX3_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 13 {ECO:0000313|Ensembl:ENSP00000465824}; Flags: Fragment;+++[K7ELD4_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 13 {ECO:0000313|Ensembl:ENSP00000466027}; Flags: Fragment;+++[K7ERH9_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 13 {ECO:0000313|Ensembl:ENSP00000468265}; Flags: Fragment;"]
[90338,"'ZNF160'",415,399.03,359,391.01,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0070009///serine-type aminopeptidase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0004252///serine-type endopeptidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008236///serine-type peptidase activity","GO:0030193///regulation of blood coagulation+++GO:0007596///blood coagulation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031639///plasminogen activation+++GO:0007599///hemostasis+++GO:0007597///blood coagulation, intrinsic pathway+++GO:0051919///positive regulation of fibrinolysis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030097///hemopoiesis+++GO:0006508///proteolysis","zinc finger protein 160","[ZN160_HUMAN|Reviewed]RecName: Full=Zinc finger protein 160; AltName: Full=Zinc finger protein HZF5; AltName: Full=Zinc finger protein Kr18; Short=HKr18;+++[A0A024R4Q2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160, isoform CRA_c {ECO:0000313|EMBL:EAW72114.1};+++[D6RB32_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|Ensembl:ENSP00000424479};+++[H0Y596_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|Ensembl:ENSP00000397401}; Flags: Fragment;+++[M0QXU9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160 {ECO:0000313|Ensembl:ENSP00000469393}; Flags: Fragment;+++[M0QZ49_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160 {ECO:0000313|Ensembl:ENSP00000470305}; Flags: Fragment;+++[M0QZI7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160, isoform CRA_b {ECO:0000313|EMBL:EAW72111.1};+++[M0R285_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160 {ECO:0000313|Ensembl:ENSP00000472387}; Flags: Fragment;+++[Q9UEG0_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|EMBL:BAA20295.1}; Flags: Fragment;+++[X6R3B1_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|Ensembl:ENSP00000264691}; Flags: Fragment;"]
[90416,"'CCDC32'",362,374,317,351,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0005515///protein binding",null,"coiled-coil domain containing 32","[CCD32_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 32;+++[A0A024R9J9_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 32, isoform CRA_a {ECO:0000313|EMBL:EAW92423.1};+++[H0YLI5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 32, isoform CRA_e {ECO:0000313|EMBL:EAW92427.1}; SubName: Full=Coiled-coil domain-containing protein 32 {ECO:0000313|Ensembl:ENSP00000453221};+++[H0YLN5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 32 {ECO:0000313|Ensembl:ENSP00000453274}; Flags: Fragment;+++[H0YM19_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 32 {ECO:0000313|Ensembl:ENSP00000453429};+++[H0YMC0_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 32 {ECO:0000313|Ensembl:ENSP00000453544};+++[H0YN78_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 32 {ECO:0000313|Ensembl:ENSP00000453899}; Flags: Fragment;"]
[90529,"'STPG1'",252,308,250,270,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00604///Deafness, autosomal dominant+++H00734///Autosomal recessive congenital ichthyosis+++H01927///Van der Woude syndrome",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005622///intracellular","GO:0003674///molecular_function","GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0090073///positive regulation of protein homodimerization activity","sperm tail PG-rich repeat containing 1","[STPG1_HUMAN|Reviewed]RecName: Full=O(6)-methylguanine-induced apoptosis 2; Short=MAPO2; AltName: Full=Sperm-tail PG-rich repeat-containing protein 1;+++[A0A024RAC8_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 201, isoform CRA_b {ECO:0000313|EMBL:EAW95127.1};+++[H0Y4J3_HUMAN|Unreviewed]SubName: Full=O(6)-methylguanine-induced apoptosis 2 {ECO:0000313|Ensembl:ENSP00000392225}; Flags: Fragment;+++[Q5TH77_HUMAN|Unreviewed]SubName: Full=O(6)-methylguanine-induced apoptosis 2 {ECO:0000313|Ensembl:ENSP00000416176}; Flags: Fragment;"]
[9057,"'SLC7A6'",1748,1658,1620,1675.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0015297///antiporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity","GO:0050900///leukocyte migration+++GO:0065003///protein-containing complex assembly+++GO:0006520///cellular amino acid metabolic process+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0055085///transmembrane transport+++GO:0003333///amino acid transmembrane transport","solute carrier family 7 member 6","[YLAT2_HUMAN|Reviewed]RecName: Full=Y+L amino acid transporter 2; AltName: Full=Cationic amino acid transporter, y+ system; AltName: Full=Solute carrier family 7 member 6; AltName: Full=y(+)L-type amino acid transporter 2; Short=Y+LAT2; Short=y+LAT-2;+++[A0A024R719_HUMAN|Unreviewed]SubName: Full=Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 6, isoform CRA_a {ECO:0000313|EMBL:EAW83220.1};+++[A0AUM0_HUMAN|Unreviewed]SubName: Full=SLC7A6 protein {ECO:0000313|EMBL:AAI13101.1}; Flags: Fragment;+++[E7EPZ8_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000368448};+++[H3BNF5_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000454824};+++[H3BPK5_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000455357}; Flags: Fragment;+++[H3BPV6_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000455487}; Flags: Fragment;+++[H3BRZ8_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000456474}; Flags: Fragment;+++[H3BSB6_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000456629}; Flags: Fragment;+++[H3BSV7_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000456896}; Flags: Fragment;+++[H3BUA4_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000457550}; Flags: Fragment;+++[H3BUR2_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000457758}; Flags: Fragment;+++[J3QL60_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000463394}; Flags: Fragment;"]
[9071,"'CLDN10'",8,13,6,9,"04670///Leukocyte transendothelial migration+++04530///Tight junction+++04514///Cell adhesion molecules (CAMs)+++05160///Hepatitis C","H00742///Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome+++H01439///Williams-Beuren syndrome+++H00605///Deafness, autosomal recessive+++H01210///Hypomagnesemia",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005923///bicellular tight junction","GO:0042802///identical protein binding+++GO:0005198///structural molecule activity","GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0007155///cell adhesion+++GO:0043269///regulation of ion transport+++GO:0006811///ion transport","claudin 10","[CLD10_HUMAN|Reviewed]RecName: Full=Claudin-10; AltName: Full=Oligodendrocyte-specific protein-like; Short=OSP-like;+++[Q5W075_HUMAN|Unreviewed]SubName: Full=Claudin-10 {ECO:0000313|Ensembl:ENSP00000366051};"]
[9077,"'DIRAS3'",48,45,43,45.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding","GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006349///regulation of gene expression by genetic imprinting","DIRAS family GTPase 3","[DIRA3_HUMAN|Reviewed]RecName: Full=GTP-binding protein Di-Ras3; AltName: Full=Distinct subgroup of the Ras family member 3; AltName: Full=Rho-related GTP-binding protein RhoI; Flags: Precursor;"]
[90865,"'IL33'",40,25,23,29.3333333333333,"05164///Influenza A+++04623///Cytosolic DNA-sensing pathway+++04060///Cytokine-cytokine receptor interaction+++04217///Necroptosis",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005694///chromosome+++GO:0005615///extracellular space+++GO:0030133///transport vesicle+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005125///cytokine activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061518///microglial cell proliferation+++GO:0038172///interleukin-33-mediated signaling pathway+++GO:0051607///defense response to virus+++GO:0050729///positive regulation of inflammatory response+++GO:0032753///positive regulation of interleukin-4 production+++GO:0002281///macrophage activation involved in immune response+++GO:0002686///negative regulation of leukocyte migration+++GO:0090197///positive regulation of chemokine secretion+++GO:0016579///protein deubiquitination+++GO:0010628///positive regulation of gene expression+++GO:0010469///regulation of signaling receptor activity+++GO:0002830///positive regulation of type 2 immune response+++GO:0002282///microglial cell activation involved in immune response+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032689///negative regulation of interferon-gamma production+++GO:0032754///positive regulation of interleukin-5 production+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0032755///positive regulation of interleukin-6 production+++GO:0150078///positive regulation of neuroinflammatory response+++GO:0051025///negative regulation of immunoglobulin secretion+++GO:0032736///positive regulation of interleukin-13 production+++GO:0043032///positive regulation of macrophage activation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0002826///negative regulation of T-helper 1 type immune response","interleukin 33","[IL33_HUMAN|Reviewed]RecName: Full=Interleukin-33; Short=IL-33; AltName: Full=Interleukin-1 family member 11; Short=IL-1F11; AltName: Full=Nuclear factor from high endothelial venules; Short=NF-HEV; Contains: RecName: Full=Interleukin-33 (95-270); Contains: RecName: Full=Interleukin-33 (99-270); Contains: RecName: Full=Interleukin-33 (109-270); Flags: Precursor;+++[A0A1I9RI50_HUMAN|Unreviewed]SubName: Full=Interleukin-33 {ECO:0000313|EMBL:AOZ26494.1};+++[A0A1I9RI51_HUMAN|Unreviewed]SubName: Full=Interleukin-33 {ECO:0000313|EMBL:AOZ26495.1};+++[L8ECM0_HUMAN|Unreviewed]SubName: Full=Alternative protein IL33 {ECO:0000313|EMBL:CCQ43802.1};"]
[90956,"'ADCK2'",176,179,170,175,null,"H00999///Coenzyme Q10 deficiency+++H01891///Autosomal recessive spinocerebellar ataxias+++H01657///Nephrotic syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation","aarF domain containing kinase 2","[ADCK2_HUMAN|Reviewed]RecName: Full=Uncharacterized aarF domain-containing protein kinase 2; EC=2.7.11.-;+++[A4D1T6_HUMAN|Unreviewed]SubName: Full=AarF domain containing kinase 2 {ECO:0000313|EMBL:EAL24025.1}; SubName: Full=AarF domain containing kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW83956.1};+++[C9JE15_HUMAN|Unreviewed]SubName: Full=Uncharacterized aarF domain-containing protein kinase 2 {ECO:0000313|Ensembl:ENSP00000420512};+++[H7C4I2_HUMAN|Unreviewed]SubName: Full=Uncharacterized aarF domain-containing protein kinase 2 {ECO:0000313|Ensembl:ENSP00000417367}; Flags: Fragment;+++[H7C5M5_HUMAN|Unreviewed]SubName: Full=Uncharacterized aarF domain-containing protein kinase 2 {ECO:0000313|Ensembl:ENSP00000420288}; Flags: Fragment;"]
[91074,"'ANKRD30A'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","ankyrin repeat domain 30A","[AN30A_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 30A; AltName: Full=Serologically defined breast cancer antigen NY-BR-1;+++[Q5W026_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 30A {ECO:0000313|Ensembl:ENSP00000363792};+++[R4GNA2_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 30A {ECO:0000313|Ensembl:ENSP00000473551};"]
[91156,"'IGFN1'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0030018///Z disc+++GO:0005737///cytoplasm+++GO:0030017///sarcomere+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0008150///biological_process","immunoglobulin-like and fibronectin type III domain containing 1","[IGFN1_HUMAN|Reviewed]RecName: Full=Immunoglobulin-like and fibronectin type III domain-containing protein 1; AltName: Full=EEF1A2-binding protein 1; AltName: Full=KY-interacting protein 1;+++[H7BZ61_HUMAN|Unreviewed]SubName: Full=Immunoglobulin-like and fibronectin type III domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387975}; Flags: Fragment;"]
[91289,"'LMF2'",2838,2823,2625,2762,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0051604///protein maturation","lipase maturation factor 2","[LMF2_HUMAN|Reviewed]RecName: Full=Lipase maturation factor 2; AltName: Full=Transmembrane protein 112B; AltName: Full=Transmembrane protein 153;"]
[91369,"'ANKRD40'",499,469,451,473,"04976///Bile secretion+++01523///Antifolate resistance+++04140///Autophagy - animal+++04137///Mitophagy - animal+++02010///ABC transporters",{"$nulls":3},"GO:0005575///cellular_component","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0008150///biological_process","ankyrin repeat domain 40","[ANR40_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 40;+++[A8IK34_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain 40 {ECO:0000313|EMBL:ABW05020.1}; SubName: Full=cDNA, FLJ94665 {ECO:0000313|EMBL:BAG36721.1};+++[K7ERW4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000468442}; Flags: Fragment;"]
[91445,"'RNF185'",892,782,771,815,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0036513///Derlin-1 retrotranslocation complex+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0016740///transferase activity","GO:0036503///ERAD pathway+++GO:0016567///protein ubiquitination+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0055085///transmembrane transport+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0006914///autophagy","ring finger protein 185","[RN185_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF185; EC=2.3.2.27 {ECO:0000269|PubMed:21931693, ECO:0000269|PubMed:27485036}; AltName: Full=RING finger protein 185; AltName: Full=RING-type E3 ubiquitin transferase RNF185 {ECO:0000305};+++[A0A024R1F5_HUMAN|Unreviewed]SubName: Full=Ring finger protein 185, isoform CRA_e {ECO:0000313|EMBL:EAW59951.1};+++[A0A024R1H4_HUMAN|Unreviewed]SubName: Full=Ring finger protein 185, isoform CRA_g {ECO:0000313|EMBL:EAW59950.1};+++[A9X3U0_HUMAN|Unreviewed]SubName: Full=BSK65-TEST2 {ECO:0000313|EMBL:ABB97511.1}; SubName: Full=E3 ubiquitin-protein ligase RNF185 {ECO:0000313|Ensembl:ENSP00000410916};+++[B4DMD6_HUMAN|Unreviewed]SubName: Full=Ring finger protein 185, isoform CRA_h {ECO:0000313|EMBL:EAW59952.1}; SubName: Full=cDNA FLJ53598, moderately similar to RING finger protein 185 {ECO:0000313|EMBL:BAG59848.1};"]
[9156,"'EXO1'",11,10,5,8.66666666666667,"03430///Mismatch repair",{"$nulls":3},"GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm","GO:0017108///5'-flap endonuclease activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004518///nuclease activity+++GO:0003677///DNA binding+++GO:0016787///hydrolase activity+++GO:0004519///endonuclease activity+++GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0008409///5'-3' exonuclease activity+++GO:0003682///chromatin binding+++GO:0045145///single-stranded DNA 5'-3' exodeoxyribonuclease activity+++GO:0004527///exonuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0051908///double-stranded DNA 5'-3' exodeoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003690///double-stranded DNA binding+++GO:0048256///flap endonuclease activity","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000706///meiotic DNA double-strand break processing+++GO:0006298///mismatch repair+++GO:0006281///DNA repair+++GO:0051321///meiotic cell cycle+++GO:0002455///humoral immune response mediated by circulating immunoglobulin+++GO:0006310///DNA recombination+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0002376///immune system process+++GO:0006260///DNA replication+++GO:0045190///isotype switching+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090656///t-circle formation","exonuclease 1","[EXO1_HUMAN|Reviewed]RecName: Full=Exonuclease 1; Short=hExo1; EC=3.1.-.-; AltName: Full=Exonuclease I; Short=hExoI;+++[A0A024R3V2_HUMAN|Unreviewed]SubName: Full=Exonuclease 1, isoform CRA_a {ECO:0000313|EMBL:EAW70105.1};+++[A8K5H6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76659, highly similar to Homo sapiens exonuclease 1 (EXO1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83980.1};+++[E5RGY3_HUMAN|Unreviewed]SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSP00000430082}; Flags: Fragment;+++[E5RHK1_HUMAN|Unreviewed]SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSP00000429720}; Flags: Fragment;+++[H0YAZ2_HUMAN|Unreviewed]SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSP00000428326}; Flags: Fragment;+++[Q5T397_HUMAN|Unreviewed]SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSP00000415531}; Flags: Fragment;+++[Q5T398_HUMAN|Unreviewed]SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSP00000412041}; Flags: Fragment;+++[Q5T399_HUMAN|Unreviewed]SubName: Full=Exonuclease 1 {ECO:0000313|Ensembl:ENSP00000406652}; Flags: Fragment;"]
[91661,"'ZNF765'",72.92,71.96,92.13,79.0033333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 765","[ZN765_HUMAN|Reviewed]RecName: Full=Zinc finger protein 765;+++[D6RF03_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 765 {ECO:0000313|Ensembl:ENSP00000421579}; Flags: Fragment;+++[E9PDE6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 765 {ECO:0000313|Ensembl:ENSP00000425657};"]
[91748,"'ELMSAN1'",551,724,616,630.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0000118///histone deacetylase complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","ELM2 and Myb/SANT domain containing 1","[EMSA1_HUMAN|Reviewed]RecName: Full=ELM2 and SANT domain-containing protein 1; AltName: Full=MIDEAS {ECO:0000303|PubMed:25653165};+++[A0A024R689_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 43, isoform CRA_a {ECO:0000313|EMBL:EAW81128.1};+++[A0A0A0MSU2_HUMAN|Unreviewed]SubName: Full=ELM2 and SANT domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000402380}; Flags: Fragment;+++[A0A1C7CYX1_HUMAN|Unreviewed]SubName: Full=ELM2 and SANT domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000407767};+++[A0PJD3_HUMAN|Unreviewed]SubName: Full=C14orf43 protein {ECO:0000313|EMBL:AAH25330.1}; Flags: Fragment;+++[C9JYU7_HUMAN|Unreviewed]SubName: Full=ELM2 and SANT domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000401344}; Flags: Fragment;+++[H7C1L3_HUMAN|Unreviewed]SubName: Full=ELM2 and SANT domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000400871}; Flags: Fragment;+++[Q9NS11_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide specific response-68 protein {ECO:0000313|EMBL:AAF75125.1};"]
[91828,"'EXOC3L4'",1,0,0,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000145///exocyst","GO:0000149///SNARE binding","GO:0006887///exocytosis+++GO:0051601///exocyst localization","exocyst complex component 3 like 4","[EX3L4_HUMAN|Reviewed]RecName: Full=Exocyst complex component 3-like protein 4;+++[H0YNJ4_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 3-like protein 4 {ECO:0000313|Ensembl:ENSP00000454036}; Flags: Fragment;+++[H0YNV0_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 3-like protein 4 {ECO:0000313|Ensembl:ENSP00000454163}; Flags: Fragment;+++[H0YNV7_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 3-like protein 4 {ECO:0000313|Ensembl:ENSP00000454174}; Flags: Fragment;"]
[91947,"'ARRDC4'",558,423,425,468.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:1903561///extracellular vesicle+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding+++GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination","GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0140112///extracellular vesicle biogenesis+++GO:0015031///protein transport+++GO:0016567///protein ubiquitination","arrestin domain containing 4","[ARRD4_HUMAN|Reviewed]RecName: Full=Arrestin domain-containing protein 4;+++[A0A024RC80_HUMAN|Unreviewed]SubName: Full=Arrestin domain containing 4, isoform CRA_a {ECO:0000313|EMBL:EAX02214.1};+++[A8K2F6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75621, highly similar to Homo sapiens arrestin domain containing 4 (ARRDC4), mRNA {ECO:0000313|EMBL:BAF82910.1};"]
[92014,"'SLC25A51'",90,83,76,83,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport","solute carrier family 25 member 51","[S2551_HUMAN|Reviewed]RecName: Full=Solute carrier family 25 member 51; AltName: Full=Mitochondrial carrier triple repeat protein 1;+++[D3DRQ4_HUMAN|Unreviewed]SubName: Full=Mitochondrial carrier triple repeat 1, isoform CRA_a {ECO:0000313|EMBL:EAW58260.1};"]
[92154,"'MTSS1L'",6415,6624,5879,6306,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0032587///ruffle membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0001726///ruffle+++GO:0042995///cell projection+++GO:0030027///lamellipodium","GO:0003785///actin monomer binding+++GO:0003779///actin binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005096///GTPase activator activity+++GO:0048365///Rac GTPase binding","GO:0090630///activation of GTPase activity+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0097178///ruffle assembly+++GO:0007009///plasma membrane organization+++GO:0097581///lamellipodium organization+++GO:0061024///membrane organization","MTSS1L, I-BAR domain containing","[MTSSL_HUMAN|Reviewed]RecName: Full=MTSS1-like protein; AltName: Full=Actin-bundling with BAIAP2 homology protein 1; Short=ABBA-1;+++[A0A087WXN9_HUMAN|Unreviewed]SubName: Full=MTSS1-like protein {ECO:0000313|Ensembl:ENSP00000481169};+++[H3BPV0_HUMAN|Unreviewed]SubName: Full=MTSS1-like protein {ECO:0000313|Ensembl:ENSP00000455480}; Flags: Fragment;+++[I3L2G4_HUMAN|Unreviewed]SubName: Full=MTSS1-like protein {ECO:0000313|Ensembl:ENSP00000459654}; Flags: Fragment;+++[Q8TB44_HUMAN|Unreviewed]SubName: Full=MTSS1L protein {ECO:0000313|EMBL:AAH24752.1}; Flags: Fragment;"]
[92235,"'DUSP27'",9,12,3,8,null,"H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H01601///Anaplastic large-cell lymphoma+++H01892///Peripheral T cell lymphoma (PTCL)+++H01994///Lafora disease",null,null,"GO:0030017///sarcomere","GO:0008138///protein tyrosine/serine/threonine phosphatase activity",null,"dual specificity phosphatase 27, atypical","[DUS27_HUMAN|Reviewed]RecName: Full=Inactive dual specificity phosphatase 27 {ECO:0000305};"]
[9231,"'DLG5'",1848,1889,2000,1912.33333333333,{"$nulls":4},"GO:0045202///synapse+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0036064///ciliary basal body+++GO:0014069///postsynaptic density+++GO:0005913///cell-cell adherens junction+++GO:0005886///plasma membrane+++GO:0030054///cell junction","GO:0030159///receptor signaling complex scaffold activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0008013///beta-catenin binding","GO:0045186///zonula adherens assembly+++GO:0072205///metanephric collecting duct development+++GO:0060999///positive regulation of dendritic spine development+++GO:0030011///maintenance of cell polarity+++GO:0008285///negative regulation of cell proliferation+++GO:0042981///regulation of apoptotic process+++GO:0051965///positive regulation of synapse assembly+++GO:0030336///negative regulation of cell migration+++GO:0007165///signal transduction+++GO:0065003///protein-containing complex assembly+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0098609///cell-cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0030901///midbrain development+++GO:0030859///polarized epithelial cell differentiation+++GO:0071896///protein localization to adherens junction+++GO:0035331///negative regulation of hippo signaling+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0042130///negative regulation of T cell proliferation+++GO:0001837///epithelial to mesenchymal transition+++GO:0035332///positive regulation of hippo signaling+++GO:0045176///apical protein localization","discs large MAGUK scaffold protein 5","[DLG5_HUMAN|Reviewed]RecName: Full=Disks large homolog 5; AltName: Full=Discs large protein P-dlg; AltName: Full=Placenta and prostate DLG;+++[A0A0A0MSL1_HUMAN|Unreviewed]SubName: Full=Disks large homolog 5 {ECO:0000313|Ensembl:ENSP00000394797}; Flags: Fragment;+++[A0A0J9YYG8_HUMAN|Unreviewed]SubName: Full=Disks large homolog 5 {ECO:0000313|Ensembl:ENSP00000488845}; Flags: Fragment;+++[L8EAB8_HUMAN|Unreviewed]SubName: Full=Alternative protein DLG5 {ECO:0000313|EMBL:CCQ43278.1};+++[R4GMQ2_HUMAN|Unreviewed]SubName: Full=Disks large homolog 5 {ECO:0000313|Ensembl:ENSP00000473298}; Flags: Fragment;"]
[92344,"'GORAB'",226,226,235,229,"04115///p53 signaling pathway","H00558///Geroderma osteodysplasticum",null,null,"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:1905515///non-motile cilium assembly+++GO:0031069///hair follicle morphogenesis+++GO:1901622///positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning","golgin, RAB6 interacting","[GORAB_HUMAN|Reviewed]RecName: Full=RAB6-interacting golgin; AltName: Full=N-terminal kinase-like-binding protein 1; Short=NTKL-BP1; Short=NTKL-binding protein 1; Short=hNTKL-BP1; AltName: Full=SCY1-like 1-binding protein 1; Short=SCYL1-BP1; Short=SCYL1-binding protein 1;+++[A0A024R923_HUMAN|Unreviewed]SubName: Full=SCY1-like 1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW90879.1};+++[B3KQ87_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33099 fis, clone TRACH2000807, highly similar to Homo sapiens SCY1-like 1 binding protein 1 (SCYL1BP1), mRNA {ECO:0000313|EMBL:BAG51949.1};+++[R4GMT2_HUMAN|Unreviewed]SubName: Full=RAB6-interacting golgin {ECO:0000313|Ensembl:ENSP00000473336}; Flags: Fragment;"]
[92558,"'BICDL1'",358,370,302,343.333333333333,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0017137///Rab GTPase binding+++GO:0034452///dynactin binding","GO:0031175///neuron projection development+++GO:0007399///nervous system development+++GO:0055107///Golgi to secretory granule transport","BICD family like cargo adaptor 1","[BICL1_HUMAN|Reviewed]RecName: Full=BICD family-like cargo adapter 1; AltName: Full=Bicaudal D-related protein 1; Short=BICD-related protein 1; Short=BICDR-1; AltName: Full=Coiled-coil domain-containing protein 64A; Short=CCDC64A;+++[H0YHP2_HUMAN|Unreviewed]SubName: Full=BICD family-like cargo adapter 1 {ECO:0000313|Ensembl:ENSP00000447477}; Flags: Fragment;+++[H0YHW1_HUMAN|Unreviewed]SubName: Full=BICD family-like cargo adapter 1 {ECO:0000313|Ensembl:ENSP00000447939}; Flags: Fragment;+++[H0YIC1_HUMAN|Unreviewed]SubName: Full=BICD family-like cargo adapter 1 {ECO:0000313|Ensembl:ENSP00000449064}; Flags: Fragment;"]
[92597,"'MOB1B'",130,92,121,114.333333333333,"04111///Cell cycle - yeast+++04392///Hippo signaling pathway - multiple species+++04391///Hippo signaling pathway - fly+++04390///Hippo signaling pathway",null,"M00683///Hippo signaling",null,"GO:0070062///extracellular exosome+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0019900///kinase binding+++GO:0016301///kinase activity+++GO:0019209///kinase activator activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0035329///hippo signaling+++GO:0033674///positive regulation of kinase activity+++GO:0031952///regulation of protein autophosphorylation+++GO:0016310///phosphorylation","MOB kinase activator 1B","[MOB1B_HUMAN|Reviewed]RecName: Full=MOB kinase activator 1B; AltName: Full=Mob1 homolog 1A; Short=Mob1A; AltName: Full=Mob1B; AltName: Full=Mps one binder kinase activator-like 1A;+++[B3KSH6_HUMAN|Unreviewed]SubName: Full=MOB1, Mps One Binder kinase activator-like 1A (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAX05635.1}; SubName: Full=cDNA FLJ36226 fis, clone THYMU2001018, highly similar to Mps one binder kinase activator-like 1A {ECO:0000313|EMBL:BAG52738.1};+++[D6RCK3_HUMAN|Unreviewed]SubName: Full=MOB kinase activator 1B {ECO:0000313|Ensembl:ENSP00000427216}; Flags: Fragment;+++[Q4W5E0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MOB4A {ECO:0000313|EMBL:AAY41047.1}; Flags: Fragment;"]
[9275,"'BCL7B'",952,811,829,864,{"$nulls":4},"GO:0005575///cellular_component","GO:0005515///protein binding+++GO:0003779///actin binding","GO:0006915///apoptotic process+++GO:0016055///Wnt signaling pathway+++GO:0008150///biological_process+++GO:0030154///cell differentiation","BCL tumor suppressor 7B","[BCL7B_HUMAN|Reviewed]RecName: Full=B-cell CLL/lymphoma 7 protein family member B; AltName: Allergen=Hom s 3;+++[F2Z3H6_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member B {ECO:0000313|Ensembl:ENSP00000411073}; SubName: Full=B-cell CLL/lymphoma 7B, isoform CRA_a {ECO:0000313|EMBL:EAW69675.1};+++[F8WDZ4_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member B {ECO:0000313|Ensembl:ENSP00000414473};+++[F8WE18_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member B {ECO:0000313|Ensembl:ENSP00000414231};"]
[9289,"'ADGRG1'",164,133,112,136.333333333333,null,"H00271///Polymicrogyria",null,null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0045121///membrane raft+++GO:0097451///glial limiting end-foot+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0004930///G protein-coupled receptor activity+++GO:0050840///extracellular matrix binding+++GO:0005518///collagen binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0008201///heparin binding","GO:0007267///cell-cell signaling+++GO:0007165///signal transduction+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:0045785///positive regulation of cell adhesion+++GO:0021819///layer formation in cerebral cortex+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0016477///cell migration+++GO:2001223///negative regulation of neuron migration+++GO:0070528///protein kinase C signaling+++GO:0021801///cerebral cortex radial glia guided migration+++GO:0007266///Rho protein signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0021796///cerebral cortex regionalization+++GO:0001525///angiogenesis+++GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0010573///vascular endothelial growth factor production+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0072520///seminiferous tubule development+++GO:0007186///G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor G1","[AGRG1_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor G1; AltName: Full=G-protein coupled receptor 56; AltName: Full=Protein TM7XN1; Contains: RecName: Full=ADGRG1 N-terminal fragment; Short=ADGRG1 NT; AltName: Full=GPR56 N-terminal fragment; Short=GPR56 NT; Short=GPR56(N); AltName: Full=GPR56 extracellular subunit; AltName: Full=GPR56 subunit alpha; Contains: RecName: Full=ADGRG1 C-terminal fragment; Short=ADGRG1 CT; AltName: Full=GPR56 C-terminal fragment; Short=GPR56 CT; Short=GPR56(C); AltName: Full=GPR56 seven-transmembrane subunit; Short=GPR56 7TM; AltName: Full=GPR56 subunit beta; Flags: Precursor;+++[A0A024R6U7_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 56 isoform 1 {ECO:0000313|EMBL:ALQ33930.1}; SubName: Full=G protein-coupled receptor 56, isoform CRA_b {ECO:0000313|EMBL:EAW82941.1};+++[A0A0S2Z517_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 56 isoform 2 {ECO:0000313|EMBL:ALQ33931.1}; SubName: Full=Testicular tissue protein Li 77 {ECO:0000313|EMBL:AEE60990.1}; Flags: Fragment;+++[A0A1B0GX62_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457307}; Flags: Fragment;+++[B3KQN7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90789 fis, clone THYRO1001523, highly similar to G-protein coupled receptor 56 {ECO:0000313|EMBL:BAG52099.1};+++[B3KQV4_HUMAN|Unreviewed]SubName: Full=cDNA PSEC0255 fis, clone NT2RP3003536, highly similar to G-protein coupled receptor 56 {ECO:0000313|EMBL:BAG52166.1};+++[B4DM06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54072, highly similar to G-protein coupled receptor 56 {ECO:0000313|EMBL:BAG59718.1};+++[H3BM73_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454263}; Flags: Fragment;+++[H3BMC2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454321}; Flags: Fragment;+++[H3BMF8_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454364}; Flags: Fragment;+++[H3BMY9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454607}; Flags: Fragment;+++[H3BNH4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454855}; Flags: Fragment;+++[H3BNN3_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454933}; Flags: Fragment;+++[H3BP67_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455176}; Flags: Fragment;+++[H3BP94_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455209}; Flags: Fragment;+++[H3BPA6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455226}; Flags: Fragment;+++[H3BPC0_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455245};+++[H3BQ11_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455553}; Flags: Fragment;+++[H3BQ46_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455600}; Flags: Fragment;+++[H3BQJ9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455812}; Flags: Fragment;+++[H3BQW4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455965}; Flags: Fragment;+++[H3BQZ1_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456002}; Flags: Fragment;+++[H3BRA1_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456147}; Flags: Fragment;+++[H3BRB4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456166}; Flags: Fragment;+++[H3BRH0_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456238}; Flags: Fragment;+++[H3BRI2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456256}; Flags: Fragment;+++[H3BRI7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456263}; Flags: Fragment;+++[H3BRZ4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456469}; Flags: Fragment;+++[H3BS14_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456494}; Flags: Fragment;+++[H3BS54_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456544}; Flags: Fragment;+++[H3BS94_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456599}; Flags: Fragment;+++[H3BS98_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456603}; Flags: Fragment;+++[H3BSB8_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456632}; Flags: Fragment;+++[H3BSF7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456682}; Flags: Fragment;+++[H3BSJ6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456731}; Flags: Fragment;+++[H3BSN3_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456781}; Flags: Fragment;+++[H3BSN7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456787}; Flags: Fragment;+++[H3BSP5_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456796}; Flags: Fragment;+++[H3BSR1_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456819}; Flags: Fragment;+++[H3BT88_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457073}; Flags: Fragment;+++[H3BTD2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457122}; Flags: Fragment;+++[H3BTH7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457178}; Flags: Fragment;+++[H3BTK9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457223}; Flags: Fragment;+++[H3BUF5_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457612};+++[H3BUH2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457635}; Flags: Fragment;+++[H3BUI6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457657}; Flags: Fragment;+++[H3BUU6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457806}; Flags: Fragment;+++[H3BV52_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457953}; Flags: Fragment;+++[H3BV72_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457979}; Flags: Fragment;+++[H3BV84_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457994}; Flags: Fragment;+++[H3BVA0_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000458014}; Flags: Fragment;+++[H3BVD3_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000458063}; Flags: Fragment;+++[H3BVE9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000458087}; Flags: Fragment;"]
[9295,"'SRSF11'",1940,2213,1912,2021.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031124///mRNA 3'-end processing","serine and arginine rich splicing factor 11","[SRS11_HUMAN|Reviewed]RecName: Full=Serine/arginine-rich splicing factor 11; AltName: Full=Arginine-rich 54 kDa nuclear protein; Short=p54; AltName: Full=Splicing factor, arginine/serine-rich 11;+++[B4DWT1_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000474372}; SubName: Full=cDNA FLJ52287, highly similar to Splicing factor arginine/serine-rich 11 {ECO:0000313|EMBL:BAG63143.1};+++[Q05BU6_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH32727.1}; Flags: Fragment;+++[Q5T757_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000359987};+++[Q5T760_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000378568}; Flags: Fragment;+++[Q6PJB9_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH17359.1}; Flags: Fragment;+++[Q6PJY9_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH09840.1}; Flags: Fragment;+++[Q6PKC9_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH02784.1}; Flags: Fragment;+++[S4R3C4_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000474149};"]
[93145,"'OLFM2'",786,590,548,641.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0030054///cell junction+++GO:0032281///AMPA glutamate receptor complex+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0005737///cytoplasm+++GO:0099243///extrinsic component of synaptic membrane+++GO:0097060///synaptic membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding","GO:1905174///regulation of vascular smooth muscle cell dedifferentiation+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0007601///visual perception+++GO:0007626///locomotory behavior+++GO:0009306///protein secretion","olfactomedin 2","[NOE2_HUMAN|Reviewed]RecName: Full=Noelin-2; AltName: Full=Olfactomedin-2; Flags: Precursor;+++[K7EIS8_HUMAN|Unreviewed]SubName: Full=Noelin-2 {ECO:0000313|Ensembl:ENSP00000464877};+++[K7EKW2_HUMAN|Unreviewed]SubName: Full=Noelin-2 {ECO:0000313|Ensembl:ENSP00000465809}; Flags: Fragment;+++[K7ELC6_HUMAN|Unreviewed]SubName: Full=Noelin-2 {ECO:0000313|Ensembl:ENSP00000466018};+++[L8E9J3_HUMAN|Unreviewed]SubName: Full=Alternative protein OLFM2 {ECO:0000313|EMBL:CCQ43814.1};"]
[9321,"'TRIP11'",675,823.01,681.18,726.396666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0002080///acrosomal membrane+++GO:0030133///transport vesicle+++GO:0005929///cilium+++GO:0002079///inner acrosomal membrane+++GO:0005794///Golgi apparatus+++GO:0002081///outer acrosomal membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0005801///cis-Golgi network+++GO:0000139///Golgi membrane","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding","GO:0060122///inner ear receptor cell stereocilium organization+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0006366///transcription by RNA polymerase II+++GO:0003281///ventricular septum development+++GO:0006486///protein glycosylation+++GO:0007030///Golgi organization+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0060348///bone development+++GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis","thyroid hormone receptor interactor 11","[TRIPB_HUMAN|Reviewed]RecName: Full=Thyroid receptor-interacting protein 11; Short=TR-interacting protein 11; Short=TRIP-11; AltName: Full=Clonal evolution-related gene on chromosome 14 protein; AltName: Full=Golgi-associated microtubule-binding protein 210; Short=GMAP-210; AltName: Full=Trip230;+++[G3V4R7_HUMAN|Unreviewed]SubName: Full=Thyroid receptor-interacting protein 11 {ECO:0000313|Ensembl:ENSP00000451944}; Flags: Fragment;+++[H0YJ97_HUMAN|Unreviewed]SubName: Full=Thyroid receptor-interacting protein 11 {ECO:0000313|Ensembl:ENSP00000451032}; Flags: Fragment;+++[H0YJI2_HUMAN|Unreviewed]SubName: Full=Thyroid receptor-interacting protein 11 {ECO:0000313|Ensembl:ENSP00000451607}; Flags: Fragment;"]
[9341,"'VAMP3'",1894,1628,1566,1696,"04130///SNARE interactions in vesicular transport+++04145///Phagosome",{"$nulls":3},"GO:0005829///cytosol+++GO:0030670///phagocytic vesicle membrane+++GO:0030133///transport vesicle+++GO:0055038///recycling endosome membrane+++GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0031201///SNARE complex+++GO:0005622///intracellular+++GO:0045202///synapse+++GO:0031410///cytoplasmic vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0055037///recycling endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043005///neuron projection+++GO:0009986///cell surface+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0030136///clathrin-coated vesicle+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0043229///intracellular organelle+++GO:0016020///membrane+++GO:0045335///phagocytic vesicle+++GO:0032588///trans-Golgi network membrane","GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding","GO:0035493///SNARE complex assembly+++GO:0001921///positive regulation of receptor recycling+++GO:0061024///membrane organization+++GO:1903531///negative regulation of secretion by cell+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0065003///protein-containing complex assembly+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0016192///vesicle-mediated transport+++GO:1903593///regulation of histamine secretion by mast cell+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0006904///vesicle docking involved in exocytosis+++GO:0071346///cellular response to interferon-gamma+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0017156///calcium ion regulated exocytosis+++GO:0070254///mucus secretion+++GO:0006887///exocytosis+++GO:0015031///protein transport","vesicle associated membrane protein 3","[VAMP3_HUMAN|Reviewed]RecName: Full=Vesicle-associated membrane protein 3; Short=VAMP-3; AltName: Full=Cellubrevin; Short=CEB; AltName: Full=Synaptobrevin-3;+++[K7EKX0_HUMAN|Unreviewed]SubName: Full=Vesicle-associated membrane protein 3 {ECO:0000313|Ensembl:ENSP00000465820};+++[Q6FGG2_HUMAN|Unreviewed]SubName: Full=VAMP3 protein {ECO:0000313|EMBL:CAG46942.1}; SubName: Full=Vesicle-associated membrane protein 3 (Cellubrevin) {ECO:0000313|EMBL:EAW71582.1}; SubName: Full=cDNA, FLJ92013, Homo sapiens vesicle-associated membrane protein 3 (cellubrevin)(VAMP3), mRNA {ECO:0000313|EMBL:BAG38147.1};"]
[9355,"'LHX2'",7688,7144,6585,7139,{"$nulls":4},"GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding","GO:0021978///telencephalon regionalization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001942///hair follicle development+++GO:0009953///dorsal/ventral pattern formation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0022008///neurogenesis+++GO:0060041///retina development in camera-type eye+++GO:0021537///telencephalon development+++GO:0007411///axon guidance+++GO:0007498///mesoderm development+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007420///brain development+++GO:0001843///neural tube closure+++GO:0007399///nervous system development+++GO:0021987///cerebral cortex development+++GO:0048675///axon extension+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0021772///olfactory bulb development+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:0030182///neuron differentiation+++GO:0045814///negative regulation of gene expression, epigenetic","LIM homeobox 2","[LHX2_HUMAN|Reviewed]RecName: Full=LIM/homeobox protein Lhx2; Short=Homeobox protein LH-2; Short=LIM homeobox protein 2;+++[B3KNJ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14691 fis, clone NT2RP2005325, highly similar to LIM/homeobox protein Lhx2 {ECO:0000313|EMBL:BAG51357.1};+++[H0YM35_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000453448}; Flags: Fragment;+++[H7C0H1_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000394978}; Flags: Fragment;+++[U3KQT5_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000476200}; Flags: Fragment;"]
[93627,"'TBCK'",603.15,561.4,465.12,543.223333333333,null,"H01922///Infantile hypotonia with psychomotor retardation and characteristic facies",null,null,"GO:0005856///cytoskeleton+++GO:0072686///mitotic spindle+++GO:0005819///spindle+++GO:0005737///cytoplasm+++GO:0030496///midbody","GO:0017137///Rab GTPase binding+++GO:0005524///ATP binding+++GO:0005096///GTPase activator activity+++GO:0004672///protein kinase activity","GO:0008283///cell proliferation+++GO:0032006///regulation of TOR signaling+++GO:0030036///actin cytoskeleton organization+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity+++GO:0006468///protein phosphorylation","TBC1 domain containing kinase","[TBCK_HUMAN|Reviewed]RecName: Full=TBC domain-containing protein kinase-like protein;+++[A0A024RDH3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX06202.1};+++[D6R950_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000423637}; Flags: Fragment;+++[D6RC61_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000423834}; Flags: Fragment;+++[D6RDG2_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000420985}; Flags: Fragment;+++[D6RDY5_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000425197}; Flags: Fragment;+++[H0Y8U7_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000422160}; Flags: Fragment;+++[H0Y959_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000423092}; Flags: Fragment;+++[H0YA45_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000426093}; Flags: Fragment;+++[Q5HYF5_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000421182};"]
[9378,"'NRXN1'",1,0,2,1,"04514///Cell adhesion molecules (CAMs)","H00756///Pitt-Hopkins syndrome",null,null,"GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum+++GO:0042734///presynaptic membrane+++GO:0031982///vesicle+++GO:0031965///nuclear membrane+++GO:0005730///nucleolus+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0009986///cell surface+++GO:0044295///axonal growth cone+++GO:0099056///integral component of presynaptic membrane+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0030139///endocytic vesicle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0098793///presynapse+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0099059///integral component of presynaptic active zone membrane","GO:0005102///signaling receptor binding+++GO:0050839///cell adhesion molecule binding+++GO:0038023///signaling receptor activity+++GO:0097109///neuroligin family protein binding+++GO:0005246///calcium channel regulator activity+++GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0033130///acetylcholine receptor binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding","GO:0097112///gamma-aminobutyric acid receptor clustering+++GO:1900020///positive regulation of protein kinase C activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0097116///gephyrin clustering involved in postsynaptic density assembly+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0001525///angiogenesis+++GO:0097104///postsynaptic membrane assembly+++GO:2000311///regulation of AMPA receptor activity+++GO:0071625///vocalization behavior+++GO:0035176///social behavior+++GO:0042297///vocal learning+++GO:0051965///positive regulation of synapse assembly+++GO:0031175///neuron projection development+++GO:0097114///NMDA glutamate receptor clustering+++GO:1905520///positive regulation of presynaptic active zone assembly+++GO:0007612///learning+++GO:0097119///postsynaptic density protein 95 clustering+++GO:0030534///adult behavior+++GO:0097091///synaptic vesicle clustering+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0021707///cerebellar granule cell differentiation+++GO:0090129///positive regulation of synapse maturation+++GO:0007155///cell adhesion+++GO:0010629///negative regulation of gene expression+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1905606///regulation of presynapse assembly+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0097105///presynaptic membrane assembly+++GO:2000310///regulation of NMDA receptor activity+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0007411///axon guidance+++GO:0007269///neurotransmitter secretion+++GO:0090126///protein-containing complex assembly involved in synapse maturation+++GO:0045184///establishment of protein localization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0050885///neuromuscular process controlling balance+++GO:0051490///negative regulation of filopodium assembly+++GO:2000821///regulation of grooming behavior+++GO:0099151///regulation of postsynaptic density assembly+++GO:0098693///regulation of synaptic vesicle cycle+++GO:0097117///guanylate kinase-associated protein clustering+++GO:0099150///regulation of postsynaptic specialization assembly+++GO:0007158///neuron cell-cell adhesion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007416///synapse assembly+++GO:0007268///chemical synaptic transmission+++GO:0035418///protein localization to synapse+++GO:0099560///synaptic membrane adhesion+++GO:0097120///receptor localization to synapse+++GO:0071277///cellular response to calcium ion+++GO:0023041///neuronal signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0099542///trans-synaptic signaling by endocannabinoid+++GO:0007165///signal transduction+++GO:0060134///prepulse inhibition","neurexin 1","[NRX1A_HUMAN|Reviewed]RecName: Full=Neurexin-1; AltName: Full=Neurexin I-alpha; AltName: Full=Neurexin-1-alpha; Flags: Precursor;+++[NRX1B_HUMAN|Reviewed]RecName: Full=Neurexin-1-beta; AltName: Full=Neurexin I-beta; Flags: Precursor;+++[A0A0D9SEJ1_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000485723};+++[A0A0D9SEM5_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000485815};+++[A0A0D9SEP4_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000485887};+++[A0A0D9SEQ7_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000485912};+++[A0A0D9SF07_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000486185}; Flags: Fragment;+++[A0A0D9SF36_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000486253}; Flags: Fragment;+++[A0A0D9SFF4_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000486544};+++[A0A0D9SFY6_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000486993};+++[A0A0D9SG60_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000487165}; Flags: Fragment;+++[A0A0D9SG96_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000487268}; Flags: Fragment;+++[A0A0R4J2G7_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000434015};+++[A0A0U1RQP8_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000489108};+++[A0A0U1RR00_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000489258};+++[A0A0U1RRK7_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000489573};+++[A0A1B0GTL0_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000489745};+++[A0A1B0GU94_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000490017}; Flags: Fragment;+++[A0A1B0GUQ1_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000490198}; Flags: Fragment;+++[A0A1B0GUR2_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000490210}; Flags: Fragment;+++[A0A1B0GVF4_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000490494};+++[A0A1D5RMU6_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000486879};+++[A4FVB9_HUMAN|Unreviewed]SubName: Full=NRXN1 protein {ECO:0000313|EMBL:AAI25180.1}; Flags: Fragment;+++[E7EQN4_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000385310};+++[E7ERL8_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000385017};+++[F5GYC7_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000385434};+++[F8WB18_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000385681};+++[H0Y568_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000396738};+++[H7BYC7_HUMAN|Unreviewed]SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000367510};+++[Q08AH0_HUMAN|Unreviewed]SubName: Full=NRXN1 protein {ECO:0000313|EMBL:AAI25181.1}; SubName: Full=Neurexin-1-beta {ECO:0000313|Ensembl:ENSP00000483634};+++[Q49A31_HUMAN|Unreviewed]SubName: Full=NRXN1 protein {ECO:0000313|EMBL:AAH46631.1};"]
[9397,"'NMT2'",258.69,273,259,263.563333333333,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0019898///extrinsic component of membrane+++GO:0043657///host cell","GO:0016746///transferase activity, transferring acyl groups+++GO:0004379///glycylpeptide N-tetradecanoyltransferase activity+++GO:0016740///transferase activity","GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0075733///intracellular transport of virus+++GO:0018008///N-terminal peptidyl-glycine N-myristoylation+++GO:0006499///N-terminal protein myristoylation","N-myristoyltransferase 2","[NMT2_HUMAN|Reviewed]RecName: Full=Glycylpeptide N-tetradecanoyltransferase 2; EC=2.3.1.97 {ECO:0000269|PubMed:25255805, ECO:0000269|PubMed:9506952}; AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase 2; Short=NMT 2; AltName: Full=Peptide N-myristoyltransferase 2; AltName: Full=Type II N-myristoyltransferase;+++[B3KT39_HUMAN|Unreviewed]RecName: Full=Glycylpeptide N-tetradecanoyltransferase {ECO:0000256|RuleBase:RU000586}; EC=2.3.1.97 {ECO:0000256|RuleBase:RU000586};+++[Q5VUC6_HUMAN|Unreviewed]RecName: Full=Glycylpeptide N-tetradecanoyltransferase {ECO:0000256|RuleBase:RU000586}; EC=2.3.1.97 {ECO:0000256|RuleBase:RU000586};+++[Q5VUC7_HUMAN|Unreviewed]RecName: Full=Glycylpeptide N-tetradecanoyltransferase {ECO:0000256|RuleBase:RU000586}; EC=2.3.1.97 {ECO:0000256|RuleBase:RU000586};+++[Q9BS83_HUMAN|Unreviewed]RecName: Full=Glycylpeptide N-tetradecanoyltransferase {ECO:0000256|RuleBase:RU000586}; EC=2.3.1.97 {ECO:0000256|RuleBase:RU000586}; Flags: Fragment;"]
[9398,"'CD101'",9,2,4,5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane","GO:0016812///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides","GO:0002763///positive regulation of myeloid leukocyte differentiation+++GO:0007166///cell surface receptor signaling pathway","CD101 molecule","[IGSF2_HUMAN|Reviewed]RecName: Full=Immunoglobulin superfamily member 2; Short=IgSF2; AltName: Full=Cell surface glycoprotein V7; AltName: Full=Glu-Trp-Ile EWI motif-containing protein 101; Short=EWI-101; AltName: CD_antigen=CD101; Flags: Precursor;+++[A0A1L7MZP9_HUMAN|Unreviewed]SubName: Full=CD101 molecule {ECO:0000313|EMBL:BAW18709.1}; Flags: Fragment;+++[A0A1L7MZR3_HUMAN|Unreviewed]SubName: Full=CD101 molecule {ECO:0000313|EMBL:BAW18707.1}; Flags: Fragment;+++[A0A1L7MZY4_HUMAN|Unreviewed]SubName: Full=CD101 molecule {ECO:0000313|EMBL:BAW18708.1}; Flags: Fragment;"]
[9404,"'LPXN'",26,34,30,30,{"$nulls":4},"GO:0005925///focal adhesion+++GO:0016607///nuclear speck+++GO:0002102///podosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0050859///negative regulation of B cell receptor signaling pathway+++GO:1903506///regulation of nucleic acid-templated transcription+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0065003///protein-containing complex assembly+++GO:0007155///cell adhesion+++GO:0007162///negative regulation of cell adhesion","leupaxin","[LPXN_HUMAN|Reviewed]RecName: Full=Leupaxin;+++[B7Z5P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51550, highly similar to Leupaxin {ECO:0000313|EMBL:BAH12983.1};+++[E9PNX9_HUMAN|Unreviewed]SubName: Full=Leupaxin {ECO:0000313|Ensembl:ENSP00000437094};"]
[94234,"'FOXQ1'",222,118,108,149.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0009653///anatomical structure morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031069///hair follicle morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II","forkhead box Q1","[FOXQ1_HUMAN|Reviewed]RecName: Full=Forkhead box protein Q1; AltName: Full=HNF-3/forkhead-like protein 1; Short=HFH-1; AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 1;"]
[94239,"'H2AFV'",662.91,598,615.96,625.623333333333,"04217///Necroptosis+++05322///Systemic lupus erythematosus+++05034///Alcoholism",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0070062///extracellular exosome+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0003674///molecular_function+++GO:0046982///protein heterodimerization activity","GO:0008150///biological_process+++GO:0006325///chromatin organization","H2A histone family member V","[H2AV_HUMAN|Reviewed]RecName: Full=Histone H2A.V; AltName: Full=H2A.F/Z;+++[C9J0D1_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};+++[C9J386_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};+++[E5RJU1_HUMAN|Unreviewed]SubName: Full=Histone H2A.V {ECO:0000313|Ensembl:ENSP00000430492};"]
[9443,"'MED7'",68,56,52,58.6666666666667,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0016592///mediator complex+++GO:0016604///nuclear body+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003712///transcription coregulator activity+++GO:0061630///ubiquitin protein ligase activity","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0019827///stem cell population maintenance+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination","mediator complex subunit 7","[MED7_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 7; Short=hMED7; AltName: Full=Activator-recruited cofactor 34 kDa component; Short=ARC34; AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 9; Short=CRSP complex subunit 9; AltName: Full=Mediator complex subunit 7; AltName: Full=RNA polymerase transcriptional regulation mediator subunit 7 homolog; AltName: Full=Transcriptional coactivator CRSP33;+++[E5RIE8_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|RuleBase:RU364060}; Flags: Fragment;+++[Q6IAZ5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|RuleBase:RU364060};"]
[9466,"'IL27RA'",9,11,9,9.66666666666667,"04060///Cytokine-cytokine receptor interaction+++04630///Jak-STAT signaling pathway+++04659///Th17 cell differentiation",{"$nulls":3},"GO:0009897///external side of plasma membrane+++GO:0043235///receptor complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0019955///cytokine binding+++GO:0045509///interleukin-27 receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity","GO:0070106///interleukin-27-mediated signaling pathway+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0048302///regulation of isotype switching to IgG isotypes+++GO:0070757///interleukin-35-mediated signaling pathway+++GO:0032729///positive regulation of interferon-gamma production+++GO:0002829///negative regulation of type 2 immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0006955///immune response+++GO:0050830///defense response to Gram-positive bacterium","interleukin 27 receptor subunit alpha","[I27RA_HUMAN|Reviewed]RecName: Full=Interleukin-27 receptor subunit alpha; Short=IL-27 receptor subunit alpha; Short=IL-27R subunit alpha; Short=IL-27R-alpha; Short=IL-27RA; AltName: Full=Cytokine receptor WSX-1; AltName: Full=Cytokine receptor-like 1; AltName: Full=Type I T-cell cytokine receptor; Short=TCCR; AltName: Full=ZcytoR1; Flags: Precursor;+++[A0A024R7I8_HUMAN|Unreviewed]SubName: Full=Interleukin 27 receptor, alpha, isoform CRA_a {ECO:0000313|EMBL:EAW84390.1};"]
[9480,"'ONECUT2'",22,31,25,26,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015629///actin cytoskeleton","GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0030335///positive regulation of cell migration+++GO:0009653///anatomical structure morphogenesis+++GO:0031018///endocrine pancreas development+++GO:0009887///animal organ morphogenesis+++GO:0045165///cell fate commitment+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0060271///cilium assembly+++GO:0048935///peripheral nervous system neuron development+++GO:0001889///liver development+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031016///pancreas development+++GO:0001952///regulation of cell-matrix adhesion+++GO:0002064///epithelial cell development","one cut homeobox 2","[ONEC2_HUMAN|Reviewed]RecName: Full=One cut domain family member 2; AltName: Full=Hepatocyte nuclear factor 6-beta; Short=HNF-6-beta; AltName: Full=One cut homeobox 2; AltName: Full=Transcription factor ONECUT-2; Short=OC-2;"]
[9501,"'RPH3AL'",13,20,33,22,{"$nulls":4},"GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005623///cell","GO:0030274///LIM domain binding+++GO:0017137///Rab GTPase binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding","GO:0017157///regulation of exocytosis+++GO:0042593///glucose homeostasis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0042493///response to drug+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis","rabphilin 3A like (without C2 domains)","[RPH3L_HUMAN|Reviewed]RecName: Full=Rab effector Noc2; AltName: Full=No C2 domains protein; AltName: Full=Rabphilin-3A-like protein;+++[A0A0J9YWA6_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000487877}; Flags: Fragment;+++[A0A0J9YX72_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000488277}; Flags: Fragment;+++[A8K7D5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77349, highly similar to Homo sapiens rabphilin 3A-like (without C2 domains), mRNA {ECO:0000313|EMBL:BAF84639.1};+++[I3L181_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000458643}; Flags: Fragment;+++[I3L1Q0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459001}; Flags: Fragment;+++[I3L2G8_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459666}; Flags: Fragment;+++[I3L2I9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459716}; Flags: Fragment;+++[I3L2N0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459795}; Flags: Fragment;+++[I3L2W0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459975}; Flags: Fragment;+++[I3L2X0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459992}; Flags: Fragment;+++[I3L308_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460080}; Flags: Fragment;+++[I3L349_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460171}; Flags: Fragment;+++[I3L3M9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460580}; Flags: Fragment;+++[I3NI49_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000461885}; Flags: Fragment;"]
[9521,"'EEF1E1'",89,75,77,80.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016020///membrane","GO:0005515///protein binding","GO:0006418///tRNA aminoacylation for protein translation+++GO:0008285///negative regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:2000774///positive regulation of cellular senescence+++GO:0006412///translation+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator","eukaryotic translation elongation factor 1 epsilon 1","[MCA3_HUMAN|Reviewed]RecName: Full=Eukaryotic translation elongation factor 1 epsilon-1; AltName: Full=Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; AltName: Full=Elongation factor p18; AltName: Full=Multisynthase complex auxiliary component p18 {ECO:0000303|PubMed:19131329};+++[D6RBD7_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000424222}; SubName: Full=HCG15559, isoform CRA_d {ECO:0000313|EMBL:EAW55230.1};+++[D6RCQ0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000425577}; Flags: Fragment;+++[H0YAH9_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000427143}; Flags: Fragment;+++[H0YAL7_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000427572}; Flags: Fragment;"]
[954,"'ENTPD2'",20,17,12,16.3333333333333,"04742///Taste transduction+++00230///Purine metabolism",null,null,"R00086///ATP phosphohydrolase   ATP + H2O <=> ADP + Orthophosphate","GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005604///basement membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016787///hydrolase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:0005524///ATP binding+++GO:0017110///nucleoside-diphosphatase activity+++GO:0000166///nucleotide binding","GO:0009181///purine ribonucleoside diphosphate catabolic process+++GO:0034656///nucleobase-containing small molecule catabolic process+++GO:0030168///platelet activation+++GO:0007186///G protein-coupled receptor signaling pathway","ectonucleoside triphosphate diphosphohydrolase 2","[ENTP2_HUMAN|Reviewed]RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 2; Short=NTPDase 2; EC=3.6.1.-; AltName: Full=CD39 antigen-like 1; AltName: Full=Ecto-ATP diphosphohydrolase 2; Short=Ecto-ATPDase 2; Short=Ecto-ATPase 2;"]
[9555,"'H2AFY'",2013,1965,1865,1947.66666666667,"04217///Necroptosis+++05322///Systemic lupus erythematosus+++05034///Alcoholism",{"$nulls":3},"GO:0000228///nuclear chromosome+++GO:0070062///extracellular exosome+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin+++GO:0000786///nucleosome+++GO:0000790///nuclear chromatin+++GO:0001739///sex chromatin+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005730///nucleolus+++GO:0000793///condensed chromosome+++GO:0005694///chromosome+++GO:0001740///Barr body","GO:0003677///DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0019899///enzyme binding+++GO:0031490///chromatin DNA binding+++GO:0019901///protein kinase binding+++GO:0000182///rDNA binding+++GO:0003682///chromatin binding+++GO:1990841///promoter-specific chromatin binding+++GO:0031492///nucleosomal DNA binding+++GO:0010385///double-stranded methylated DNA binding","GO:0045815///positive regulation of gene expression, epigenetic+++GO:0019216///regulation of lipid metabolic process+++GO:0040029///regulation of gene expression, epigenetic+++GO:1904815///negative regulation of protein localization to chromosome, telomeric region+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0071169///establishment of protein localization to chromatin+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0007549///dosage compensation+++GO:0006325///chromatin organization+++GO:0061187///regulation of chromatin silencing at rDNA+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0033128///negative regulation of histone phosphorylation+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:1902750///negative regulation of cell cycle G2/M phase transition+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0006334///nucleosome assembly+++GO:1902882///regulation of response to oxidative stress+++GO:1902883///negative regulation of response to oxidative stress+++GO:1902884///positive regulation of response to oxidative stress","H2A histone family member Y","[H2AY_HUMAN|Reviewed]RecName: Full=Core histone macro-H2A.1; Short=Histone macroH2A1; Short=mH2A1; AltName: Full=Histone H2A.y; Short=H2A/y; AltName: Full=Medulloblastoma antigen MU-MB-50.205;+++[B4DJC3_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};+++[D6RCF2_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};"]
[9573,"'GDF3'",0,0,1,0.333333333333333,"04060///Cytokine-cytokine receptor interaction","H01027///Anophthalmia and microphthalmia (A/M)+++H00852///Klippel-Feil syndrome(KFS)",null,null,"GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005615///extracellular space","GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0019901///protein kinase binding+++GO:0005160///transforming growth factor beta receptor binding","GO:0048468///cell development+++GO:0007498///mesoderm development+++GO:0090009///primitive streak formation+++GO:0045605///negative regulation of epidermal cell differentiation+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0045600///positive regulation of fat cell differentiation+++GO:0032525///somite rostral/caudal axis specification+++GO:0010469///regulation of signaling receptor activity+++GO:0030903///notochord development+++GO:0001701///in utero embryonic development+++GO:0042981///regulation of apoptotic process+++GO:0010453///regulation of cell fate commitment+++GO:0007165///signal transduction+++GO:0060395///SMAD protein signal transduction+++GO:0030509///BMP signaling pathway+++GO:0007492///endoderm development+++GO:0045662///negative regulation of myoblast differentiation+++GO:0048859///formation of anatomical boundary+++GO:0002021///response to dietary excess+++GO:0001654///eye development+++GO:0001501///skeletal system development+++GO:0043408///regulation of MAPK cascade+++GO:0030514///negative regulation of BMP signaling pathway","growth differentiation factor 3","[GDF3_HUMAN|Reviewed]RecName: Full=Growth/differentiation factor 3; Short=GDF-3; Flags: Precursor;"]
[9600,"'PITPNM1'",1268,1232,1151,1217,"04137///Mitophagy - animal+++04934///Cushing's syndrome+++04140///Autophagy - animal","H01102///Pituitary adenomas+++H01431///Cushing's syndrome+++H01864///Excessive secretion of growth hormone+++H01483///Acromegaly+++H00837///Leber congenital amaurosis (LCR)",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0030496///midbody+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005811///lipid droplet+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005815///microtubule organizing center+++GO:0032154///cleavage furrow+++GO:0032580///Golgi cisterna membrane+++GO:0044297///cell body","GO:0030971///receptor tyrosine kinase binding+++GO:0046872///metal ion binding+++GO:0070300///phosphatidic acid binding+++GO:0031210///phosphatidylcholine binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0035091///phosphatidylinositol binding+++GO:0005509///calcium ion binding+++GO:0005548///phospholipid transporter activity+++GO:0008525///phosphatidylcholine transporter activity+++GO:0005515///protein binding","GO:0006629///lipid metabolic process+++GO:0015914///phospholipid transport+++GO:0007420///brain development+++GO:0007602///phototransduction+++GO:0015031///protein transport+++GO:0006661///phosphatidylinositol biosynthetic process","phosphatidylinositol transfer protein membrane associated 1","[PITM1_HUMAN|Reviewed]RecName: Full=Membrane-associated phosphatidylinositol transfer protein 1; AltName: Full=Drosophila retinal degeneration B homolog; AltName: Full=Phosphatidylinositol transfer protein, membrane-associated 1; Short=PITPnm 1; AltName: Full=Pyk2 N-terminal domain-interacting receptor 2; Short=NIR-2;+++[A0A024R5I7_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol transfer protein, membrane-associated 1, isoform CRA_a {ECO:0000313|EMBL:EAW74643.1};+++[B2R787_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93330, highly similar to Homo sapiens phosphatidylinositol transfer protein, membrane-associated 1 (PITPNM1), mRNA {ECO:0000313|EMBL:BAG35734.1};+++[E9PMS0_HUMAN|Unreviewed]SubName: Full=Membrane-associated phosphatidylinositol transfer protein 1 {ECO:0000313|Ensembl:ENSP00000432977}; Flags: Fragment;+++[E9PMZ6_HUMAN|Unreviewed]SubName: Full=Membrane-associated phosphatidylinositol transfer protein 1 {ECO:0000313|Ensembl:ENSP00000434904}; Flags: Fragment;+++[E9PNU6_HUMAN|Unreviewed]SubName: Full=Membrane-associated phosphatidylinositol transfer protein 1 {ECO:0000313|Ensembl:ENSP00000432746}; Flags: Fragment;+++[E9PSD1_HUMAN|Unreviewed]SubName: Full=Membrane-associated phosphatidylinositol transfer protein 1 {ECO:0000313|Ensembl:ENSP00000434046}; Flags: Fragment;"]
[9617,"'MTRF1'",80,76,68,74.6666666666667,null,"H00992///Seckel syndrome",null,null,"GO:0005739///mitochondrion","GO:0003747///translation release factor activity","GO:0006412///translation+++GO:0070126///mitochondrial translational termination+++GO:0006415///translational termination+++GO:0006449///regulation of translational termination","mitochondrial translation release factor 1","[RF1M_HUMAN|Reviewed]RecName: Full=Peptide chain release factor 1, mitochondrial; Short=MRF-1; Short=MtRF-1; Flags: Precursor;+++[A0A024RDT1_HUMAN|Unreviewed]SubName: Full=Mitochondrial translational release factor 1, isoform CRA_a {ECO:0000313|EMBL:EAX08649.1};+++[A0A087WZ41_HUMAN|Unreviewed]SubName: Full=Peptide chain release factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000482339}; Flags: Fragment;+++[A0A087X1S1_HUMAN|Unreviewed]SubName: Full=Peptide chain release factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000484414};+++[Q8N6Z2_HUMAN|Unreviewed]SubName: Full=MTRF1 protein {ECO:0000313|EMBL:AAH27731.1}; SubName: Full=Mitochondrial translational release factor 1, isoform CRA_b {ECO:0000313|EMBL:EAX08650.1}; SubName: Full=Peptide chain release factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000400031};+++[X6RFD4_HUMAN|Unreviewed]SubName: Full=Peptide chain release factor 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000399279}; Flags: Fragment;"]
[9645,"'MICAL2'",1175,896,1053,1041.33333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0043914///NADPH:sulfur oxidoreductase activity+++GO:0071949///FAD binding+++GO:0046872///metal ion binding+++GO:0016174///NAD(P)H oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0003779///actin binding+++GO:0004497///monooxygenase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","GO:0001947///heart looping+++GO:0055114///oxidation-reduction process+++GO:0030042///actin filament depolymerization+++GO:0007507///heart development+++GO:0019417///sulfur oxidation+++GO:0010735///positive regulation of transcription via serum response element binding+++GO:0007010///cytoskeleton organization","microtubule associated monooxygenase, calponin and LIM domain containing 2","[MICA2_HUMAN|Reviewed]RecName: Full=[F-actin]-monooxygenase MICAL2; EC=1.14.13.225 {ECO:0000269|PubMed:24440334}; AltName: Full=Molecule interacting with CasL protein 2; Short=MICAL-2;+++[A0A2R8Y771_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000495880}; Flags: Fragment;+++[A0A2R8Y7K9_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000496085}; Flags: Fragment;+++[A0A2R8YFA9_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000494982};+++[E9PJB0_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000433818}; Flags: Fragment;+++[E9PKI3_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000433509}; Flags: Fragment;+++[E9PKW5_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000435270}; Flags: Fragment;+++[E9PL42_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000433357}; Flags: Fragment;+++[E9PNC3_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000437229}; Flags: Fragment;+++[E9PRE0_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000434209}; Flags: Fragment;+++[E9PRG5_HUMAN|Unreviewed]SubName: Full=[F-actin]-monooxygenase MICAL2 {ECO:0000313|Ensembl:ENSP00000432324}; Flags: Fragment;+++[L8EAP5_HUMAN|Unreviewed]SubName: Full=Alternative protein MICAL2 {ECO:0000313|EMBL:CCQ43448.1};"]
[9654,"'TTLL4'",7942,11909,10421,10090.6666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005856///cytoskeleton+++GO:0042995///cell projection","GO:0005524///ATP binding+++GO:0070739///protein-glutamic acid ligase activity+++GO:0015631///tubulin binding+++GO:0070740///tubulin-glutamic acid ligase activity+++GO:0000166///nucleotide binding+++GO:0016874///ligase activity","GO:0006464///cellular protein modification process+++GO:0018200///peptidyl-glutamic acid modification+++GO:0018095///protein polyglutamylation","tubulin tyrosine ligase like 4","[TTLL4_HUMAN|Reviewed]RecName: Full=Tubulin polyglutamylase TTLL4; EC=6.-.-.-; AltName: Full=Tubulin--tyrosine ligase-like protein 4;+++[A0A024R424_HUMAN|Unreviewed]SubName: Full=Tubulin tyrosine ligase-like family, member 4, isoform CRA_a {ECO:0000313|EMBL:EAW70652.1};+++[C9J3I1_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000391342}; Flags: Fragment;+++[C9J982_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000411228}; Flags: Fragment;+++[C9JB60_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000405485}; Flags: Fragment;+++[E7EX20_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000396555};+++[E9PH58_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000393332};+++[H7BZY4_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000392103}; Flags: Fragment;+++[H7C1F7_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000400068}; Flags: Fragment;+++[H7C2S3_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000407434}; Flags: Fragment;+++[H7C421_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000415197}; Flags: Fragment;+++[H7C470_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL4 {ECO:0000313|Ensembl:ENSP00000415845}; Flags: Fragment;"]
[967,"'CD63'",8731,7348,7914,7997.66666666667,"04142///Lysosome+++05205///Proteoglycans in cancer",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0035577///azurophil granule membrane+++GO:0005764///lysosome+++GO:0010008///endosome membrane+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0031088///platelet dense granule membrane+++GO:0042470///melanosome+++GO:0005765///lysosomal membrane+++GO:0097487///multivesicular body, internal vesicle+++GO:0016020///membrane+++GO:0032585///multivesicular body membrane+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0005771///multivesicular body+++GO:0031902///late endosome membrane+++GO:0031904///endosome lumen+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space","GO:0005515///protein binding","GO:0045807///positive regulation of endocytosis+++GO:0035646///endosome to melanosome transport+++GO:0043473///pigmentation+++GO:0050931///pigment cell differentiation+++GO:0048757///pigment granule maturation+++GO:0002576///platelet degranulation+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:0007166///cell surface receptor signaling pathway+++GO:0016477///cell migration+++GO:0015031///protein transport+++GO:1900746///regulation of vascular endothelial growth factor signaling pathway+++GO:0034613///cellular protein localization+++GO:2001046///positive regulation of integrin-mediated signaling pathway+++GO:0002092///positive regulation of receptor internalization+++GO:0043312///neutrophil degranulation+++GO:0007160///cell-matrix adhesion","CD63 molecule","[CD63_HUMAN|Reviewed]RecName: Full=CD63 antigen; AltName: Full=Granulophysin; AltName: Full=Lysosomal-associated membrane protein 3; Short=LAMP-3; AltName: Full=Melanoma-associated antigen ME491; AltName: Full=OMA81H; AltName: Full=Ocular melanoma-associated antigen; AltName: Full=Tetraspanin-30; Short=Tspan-30; AltName: CD_antigen=CD63;+++[A0A024RB05_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[F8VNT9_HUMAN|Unreviewed]SubName: Full=CD63 antigen {ECO:0000313|Ensembl:ENSP00000450191}; Flags: Fragment;+++[F8VV56_HUMAN|Unreviewed]SubName: Full=CD63 antigen {ECO:0000313|Ensembl:ENSP00000449654};+++[F8VWK8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[F8VX62_HUMAN|Unreviewed]SubName: Full=CD63 antigen {ECO:0000313|Ensembl:ENSP00000449435};+++[F8W022_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[W6A4U0_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[9693,"'RAPGEF2'",938,1136,987,1020.33333333333,"04530///Tight junction+++04015///Rap1 signaling pathway+++04010///MAPK signaling pathway",{"$nulls":3},"GO:0005923///bicellular tight junction+++GO:0005770///late endosome+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005768///endosome+++GO:0045202///synapse+++GO:0030139///endocytic vesicle+++GO:0032991///protein-containing complex+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005911///cell-cell junction+++GO:0016324///apical plasma membrane","GO:0030553///cGMP binding+++GO:0019992///diacylglycerol binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0030165///PDZ domain binding+++GO:0070300///phosphatidic acid binding+++GO:0005509///calcium ion binding+++GO:0005096///GTPase activator activity+++GO:0050699///WW domain binding+++GO:0005515///protein binding+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030552///cAMP binding+++GO:0017034///Rap guanyl-nucleotide exchange factor activity","GO:0090557///establishment of endothelial intestinal barrier+++GO:0035556///intracellular signal transduction+++GO:0021884///forebrain neuron development+++GO:0030154///cell differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:0001764///neuron migration+++GO:0048022///negative regulation of melanin biosynthetic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:0038180///nerve growth factor signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0010976///positive regulation of neuron projection development+++GO:0071321///cellular response to cGMP+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0007275///multicellular organism development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0048167///regulation of synaptic plasticity+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:2001214///positive regulation of vasculogenesis+++GO:0072659///protein localization to plasma membrane+++GO:1901888///regulation of cell junction assembly+++GO:0061028///establishment of endothelial barrier+++GO:0032486///Rap protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0007165///signal transduction+++GO:0021591///ventricular system development+++GO:0000165///MAPK cascade+++GO:0007218///neuropeptide signaling pathway+++GO:2001224///positive regulation of neuron migration+++GO:2000670///positive regulation of dendritic cell apoptotic process+++GO:0019933///cAMP-mediated signaling+++GO:0030033///microvillus assembly+++GO:0031175///neuron projection development+++GO:0001568///blood vessel development+++GO:0007264///small GTPase mediated signal transduction+++GO:0007399///nervous system development+++GO:0071320///cellular response to cAMP","Rap guanine nucleotide exchange factor 2","[RPGF2_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 2; AltName: Full=Cyclic nucleotide ras GEF; Short=CNrasGEF; AltName: Full=Neural RAP guanine nucleotide exchange protein; Short=nRap GEP; AltName: Full=PDZ domain-containing guanine nucleotide exchange factor 1; Short=PDZ-GEF1; AltName: Full=RA-GEF-1; AltName: Full=Ras/Rap1-associating GEF-1;+++[A0A2R8Y661_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000495298};+++[A0A2R8YGD3_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000495906};+++[D6RAK0_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000421740}; Flags: Fragment;+++[D6RC78_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000422361}; Flags: Fragment;+++[D6REY8_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000421602}; Flags: Fragment;+++[H0Y8H7_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000421083}; Flags: Fragment;+++[H0Y8N8_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000421624}; Flags: Fragment;+++[H0Y8T6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000422098}; Flags: Fragment;+++[H0Y905_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000422707}; Flags: Fragment;+++[H0YAJ8_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000427334}; Flags: Fragment;+++[Q17RH5_HUMAN|Unreviewed]SubName: Full=RAPGEF2 protein {ECO:0000313|EMBL:AAI17322.1};+++[Q4W5Q4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PDZGEF1 {ECO:0000313|EMBL:AAY40909.1}; Flags: Fragment;"]
[9700,"'ESPL1'",2,3,4,3,"04110///Cell cycle+++04111///Cell cycle - yeast+++04113///Meiosis - yeast+++04114///Oocyte meiosis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0072686///mitotic spindle+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0008234///cysteine-type peptidase activity","GO:0000070///mitotic sister chromatid segregation+++GO:0000278///mitotic cell cycle+++GO:0006915///apoptotic process+++GO:0045875///negative regulation of sister chromatid cohesion+++GO:0007059///chromosome segregation+++GO:0045143///homologous chromosome segregation+++GO:0007127///meiosis I+++GO:0051307///meiotic chromosome separation+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0000281///mitotic cytokinesis+++GO:0040001///establishment of mitotic spindle localization+++GO:0000212///meiotic spindle organization+++GO:0006508///proteolysis","extra spindle pole bodies like 1, separase","[ESPL1_HUMAN|Reviewed]RecName: Full=Separin; EC=3.4.22.49; AltName: Full=Caspase-like protein ESPL1; AltName: Full=Extra spindle poles-like 1 protein; AltName: Full=Separase;+++[H3BM31_HUMAN|Unreviewed]SubName: Full=Separin {ECO:0000313|Ensembl:ENSP00000447054};+++[H3BRX7_HUMAN|Unreviewed]SubName: Full=Separin {ECO:0000313|Ensembl:ENSP00000456450}; Flags: Fragment;"]
[971,"'CD72'",6,8,1,5,"04662///B cell receptor signaling pathway",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005102///signaling receptor binding","GO:0007155///cell adhesion","CD72 molecule","[CD72_HUMAN|Reviewed]RecName: Full=B-cell differentiation antigen CD72; AltName: Full=Lyb-2; AltName: CD_antigen=CD72;+++[A0A087X0Y7_HUMAN|Unreviewed]SubName: Full=B-cell differentiation antigen CD72 {ECO:0000313|Ensembl:ENSP00000483742};+++[Q0H7P2_HUMAN|Unreviewed]SubName: Full=CD72b {ECO:0000313|EMBL:ABA55068.1};+++[Q5T4Q7_HUMAN|Unreviewed]SubName: Full=B-cell differentiation antigen CD72 {ECO:0000313|Ensembl:ENSP00000367687};+++[Q5T4Q8_HUMAN|Unreviewed]SubName: Full=B-cell differentiation antigen CD72 {ECO:0000313|Ensembl:ENSP00000367688};+++[Q5TLF7_HUMAN|Unreviewed]SubName: Full=CD72 antigen {ECO:0000313|EMBL:BAD72863.1};+++[Q5TLF8_HUMAN|Unreviewed]SubName: Full=CD72 antigen {ECO:0000313|EMBL:BAD72862.1};+++[Q5TLF9_HUMAN|Unreviewed]SubName: Full=CD72 antigen {ECO:0000313|EMBL:BAD72861.1};+++[Q5TLG0_HUMAN|Unreviewed]SubName: Full=CD72 antigen {ECO:0000313|EMBL:BAD72860.1};+++[Q5TLG3_HUMAN|Unreviewed]SubName: Full=CD72 antigen {ECO:0000313|EMBL:BAD72857.1}; SubName: Full=CD72 antigen, isoform CRA_a {ECO:0000313|EMBL:EAW58372.1}; SubName: Full=CD72 molecule {ECO:0000313|EMBL:ABK41934.1};"]
[9726,"'ZNF646'",599,667,614,626.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 646","[ZN646_HUMAN|Reviewed]RecName: Full=Zinc finger protein 646;+++[C9J3L0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 646 {ECO:0000313|Ensembl:ENSP00000391271}; Flags: Fragment;+++[H3BSD0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 646 {ECO:0000313|Ensembl:ENSP00000456651}; Flags: Fragment;"]
[9727,"'RAB11FIP3'",1144,1289,1114,1182.33333333333,"04144///Endocytosis",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP","R01857///ATP:dGDP phosphotransferase ATP + dGDP <=> ADP + dGTP+++R02326///ATP:dCDP phosphotransferase ATP + dCDP <=> ADP + dCTP+++R03530///ATP:dIDP phosphotransferase ATP + dIDP <=> ADP + dITP+++R00139///ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP+++R00156///ATP:UDP phosphotransferase ATP + UDP <=> ADP + UTP+++R00722///ATP:IDP phosphotransferase ATP + IDP <=> ADP + ITP+++R02331///ATP:dUDP phosphotransferase ATP + dUDP <=> ADP + dUTP+++R00124///ATP:ADP phosphatransferase ATP + ADP <=> ADP + ATP+++R11895///ATP:5-fluorodeoxyuridine-diphosphate phosphotransferase ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate+++R00570///ATP:CDP phosphotransferase ATP + CDP <=> ADP + CTP+++R01137///ATP:dADP phosphotransferase ATP + dADP <=> ADP + dATP+++R11894///ATP:5-fluorouridine-diphosphate phosphotransferase ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate+++R00330///ATP:GDP phosphotransferase ATP + GDP <=> ADP + GTP+++R02093///ATP:dTDP phosphotransferase ATP + dTDP <=> ADP + dTTP","GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome+++GO:0005654///nucleoplasm+++GO:0005623///cell+++GO:0005815///microtubule organizing center+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0030139///endocytic vesicle+++GO:0055038///recycling endosome membrane+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0030306///ADP-ribosylation factor binding+++GO:0046872///metal ion binding+++GO:0051959///dynein light intermediate chain binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0017137///Rab GTPase binding","GO:0070164///negative regulation of adiponectin secretion+++GO:0032465///regulation of cytokinesis+++GO:0016192///vesicle-mediated transport+++GO:0032456///endocytic recycling+++GO:0061512///protein localization to cilium+++GO:0051301///cell division+++GO:0007049///cell cycle","RAB11 family interacting protein 3","[RFIP3_HUMAN|Reviewed]RecName: Full=Rab11 family-interacting protein 3; Short=FIP3-Rab11; Short=Rab11-FIP3; AltName: Full=Arfophilin-1; AltName: Full=EF hands-containing Rab-interacting protein; Short=Eferin; AltName: Full=MU-MB-17.148;+++[A0A0A0MSV1_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000404331}; Flags: Fragment;+++[A0A0J9YWM0_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488023}; Flags: Fragment;+++[A0A0J9YWV4_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488133}; Flags: Fragment;+++[A0A0J9YXZ3_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488615}; Flags: Fragment;+++[A0A0J9YY48_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488688}; Flags: Fragment;+++[F6X994_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000399614}; Flags: Fragment;+++[H0Y7F9_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000412502}; Flags: Fragment;+++[X6RFI8_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000399644}; Flags: Fragment;"]
[9728,"'SECISBP2L'",672,604,595,623.666666666667,{"$nulls":4},"GO:1990904///ribonucleoprotein complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0003730///mRNA 3'-UTR binding","GO:0001514///selenocysteine incorporation","SECIS binding protein 2 like","[SBP2L_HUMAN|Reviewed]RecName: Full=Selenocysteine insertion sequence-binding protein 2-like; Short=SECIS-binding protein 2-like;+++[A0A024R5R0_HUMAN|Unreviewed]SubName: Full=KIAA0256 gene product, isoform CRA_a {ECO:0000313|EMBL:EAW77362.1};+++[H0YKY4_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000452987}; Flags: Fragment;+++[H0YNT4_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000454144}; Flags: Fragment;+++[J3KPI1_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000370314}; Flags: Fragment;"]
[9729,"'KIAA0408'",2.24,0,0,0.746666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"KIAA0408","[K0408_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0408;+++[E9PQS0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000434384}; Flags: Fragment;+++[H0YEM8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000436178}; Flags: Fragment;"]
[973,"'CD79A'",18,15,17,16.6666666666667,"04662///B cell receptor signaling pathway+++05340///Primary immunodeficiency","H00085///Agammaglobulinemias",null,null,"GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0019815///B cell receptor complex+++GO:0009897///external side of plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0051289///protein homotetramerization+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0050853///B cell receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0007166///cell surface receptor signaling pathway+++GO:0042100///B cell proliferation+++GO:0042113///B cell activation","CD79a molecule","[CD79A_HUMAN|Reviewed]RecName: Full=B-cell antigen receptor complex-associated protein alpha chain; AltName: Full=Ig-alpha; AltName: Full=MB-1 membrane glycoprotein; AltName: Full=Membrane-bound immunoglobulin-associated protein; AltName: Full=Surface IgM-associated protein; AltName: CD_antigen=CD79a; Flags: Precursor;+++[M0QX61_HUMAN|Unreviewed]SubName: Full=B-cell antigen receptor complex-associated protein alpha chain {ECO:0000313|Ensembl:ENSP00000468922}; Flags: Fragment;"]
[9730,"'DCAF1'",444,497,462,467.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome+++GO:0001650///fibrillar center+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex","GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990244///histone kinase activity (H2A-T120 specific)+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0030331///estrogen receptor binding","GO:0030183///B cell differentiation+++GO:0016032///viral process+++GO:0033151///V(D)J recombination+++GO:0016310///phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1990245///histone H2A-T120 phosphorylation+++GO:0006325///chromatin organization+++GO:0016567///protein ubiquitination+++GO:0035212///cell competition in a multicellular organism","DDB1 and CUL4 associated factor 1","[DCAF1_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911}; AltName: Full=HIV-1 Vpr-binding protein; Short=VprBP; AltName: Full=Serine/threonine-protein kinase VPRBP; EC=2.7.11.1; AltName: Full=Vpr-interacting protein;"]
[9731,"'CEP104'",555,624,538,572.333333333333,null,"H00530///Joubert syndrome",null,null,"GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0005814///centriole+++GO:0000922///spindle pole","GO:0016594///glycine binding+++GO:0016595///glutamate binding+++GO:0016596///thienylcyclohexylpiperidine binding+++GO:0005515///protein binding",null,"centrosomal protein 104","[CE104_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 104 kDa; Short=Cep104;+++[H7C0J5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000395283}; Flags: Fragment;+++[J3QLL3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000463605}; Flags: Fragment;+++[Q5SR26_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000411927}; Flags: Fragment;+++[Q5SR27_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000394989}; Flags: Fragment;"]
[9732,"'DOCK4'",72,86,80,79.3333333333333,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0005096///GTPase activator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0048365///Rac GTPase binding+++GO:0017124///SH3 domain binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030165///PDZ domain binding+++GO:0005515///protein binding","GO:1904694///negative regulation of vascular smooth muscle contraction+++GO:0007264///small GTPase mediated signal transduction+++GO:0060326///cell chemotaxis+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0043547///positive regulation of GTPase activity","dedicator of cytokinesis 4","[DOCK4_HUMAN|Reviewed]RecName: Full=Dedicator of cytokinesis protein 4;+++[A0A024R749_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4, isoform CRA_a {ECO:0000313|EMBL:EAW83455.1};+++[A0A2X0SFR8_HUMAN|Unreviewed]SubName: Full=DOCK4 {ECO:0000313|EMBL:SPT35744.1}; Flags: Fragment;+++[A4D0S8_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:EAL24377.1};+++[C9J637_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406468}; Flags: Fragment;+++[C9J7D9_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406298}; Flags: Fragment;+++[C9JDB3_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000403504}; Flags: Fragment;+++[F5GXW1_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000440944};+++[F8WES4_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000393486};+++[H0Y599_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000397412}; Flags: Fragment;+++[H0Y7H7_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000412834}; Flags: Fragment;+++[Q149N2_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17695.1};+++[Q149N5_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17690.1};+++[Q149N6_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:AAI17689.1};+++[Q75MU6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DOCK4 {ECO:0000313|EMBL:AAS07431.1}; Flags: Fragment;"]
[9733,"'SART3'",655,666,679,666.666666666667,null,"H00791///Disseminated superficial actinic porokeratosis (DSAP)",null,null,"GO:0071002///U4atac/U6atac snRNP+++GO:0061574///ASAP complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005691///U6atac snRNP+++GO:0015030///Cajal body+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0071001///U4/U6 snRNP","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0030624///U6atac snRNA binding+++GO:0003676///nucleic acid binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0030621///U4 snRNA binding+++GO:0017070///U6 snRNA binding","GO:0010468///regulation of gene expression+++GO:0000902///cell morphogenesis+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0048872///homeostasis of number of cells+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006334///nucleosome assembly+++GO:0000387///spliceosomal snRNP assembly+++GO:1903586///positive regulation of histone deubiquitination+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing","spliceosome associated factor 3, U4/U6 recycling protein","[SART3_HUMAN|Reviewed]RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000305}; Short=SART-3 {ECO:0000312|EMBL:BAA78384.1}; AltName: Full=Tat-interacting protein of 110 kDa {ECO:0000303|PubMed:11959860}; Short=Tip110 {ECO:0000303|PubMed:11959860}; AltName: Full=p110 nuclear RNA-binding protein {ECO:0000303|PubMed:12032085};+++[F8VV04_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449386}; Flags: Fragment;+++[F8VVK9_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449602}; Flags: Fragment;+++[F8VZM2_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447324}; Flags: Fragment;+++[F8W667_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000446577};+++[H0YHU8_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447875}; Flags: Fragment;"]
[9734,"'HDAC9'",857,852,839,849.333333333333,"05034///Alcoholism+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0000118///histone deacetylase complex+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0035097///histone methyltransferase complex","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0071889///14-3-3 protein binding+++GO:0070491///repressing transcription factor binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0008134///transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0033558///protein deacetylase activity+++GO:0003682///chromatin binding+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding+++GO:0033613///activating transcription factor binding+++GO:0005080///protein kinase C binding+++GO:0003714///transcription corepressor activity+++GO:0016787///hydrolase activity","GO:0006954///inflammatory response+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0006325///chromatin organization+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0032703///negative regulation of interleukin-2 production+++GO:0042113///B cell activation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0007507///heart development+++GO:0032869///cellular response to insulin stimulus+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0030182///neuron differentiation+++GO:0007043///cell-cell junction assembly+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0001570///vasculogenesis+++GO:0030183///B cell differentiation+++GO:0001975///response to amphetamine+++GO:0034983///peptidyl-lysine deacetylation","histone deacetylase 9","[HDAC9_HUMAN|Reviewed]RecName: Full=Histone deacetylase 9; Short=HD9; EC=3.5.1.98; AltName: Full=Histone deacetylase 7B; Short=HD7; Short=HD7b; AltName: Full=Histone deacetylase-related protein; AltName: Full=MEF2-interacting transcription repressor MITR;+++[B5MCF1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000384017};+++[B7Z3P7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79008, highly similar to Histone deacetylase 9 {ECO:0000313|EMBL:BAH14480.1};+++[C9IZS0_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000412497}; Flags: Fragment;+++[C9J1W4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000392564}; Flags: Fragment;+++[C9J835_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000411422}; Flags: Fragment;+++[C9JD56_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000404763}; Flags: Fragment;+++[C9JLX1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000409003}; Flags: Fragment;+++[F8WDS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000415095};+++[Q75N08_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07409.1}; Flags: Fragment;+++[Q75N09_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07402.1}; Flags: Fragment;+++[Q75N10_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07401.1}; Flags: Fragment;+++[Q75N14_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07423.1}; Flags: Fragment;+++[Q75N15_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07424.1}; Flags: Fragment;+++[Q75N16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07422.1}; Flags: Fragment;+++[Q9Y6V1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAD15364.2};"]
[9735,"'KNTC1'",107,70,88,88.3333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005828///kinetochore microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:1990423///RZZ complex+++GO:0005856///cytoskeleton+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007096///regulation of exit from mitosis+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0051301///cell division","kinetochore associated 1","[KNTC1_HUMAN|Reviewed]RecName: Full=Kinetochore-associated protein 1; AltName: Full=Rough deal homolog; Short=HsROD; Short=Rod; Short=hRod;+++[E7ES84_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397992};+++[F5H5V0_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408760};+++[H0YFL5_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439119}; Flags: Fragment;+++[J3KQF2_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397140}; Flags: Fragment;"]
[9736,"'USP34'",2265,2338,2083,2228.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0004197///cysteine-type endopeptidase activity","GO:0071108///protein K48-linked deubiquitination+++GO:0006508///proteolysis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031647///regulation of protein stability+++GO:0016579///protein deubiquitination","ubiquitin specific peptidase 34","[UBP34_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 34; EC=3.4.19.12 {ECO:0000269|PubMed:14715245, ECO:0000269|PubMed:21383061}; AltName: Full=Deubiquitinating enzyme 34; AltName: Full=Ubiquitin thioesterase 34; AltName: Full=Ubiquitin-specific-processing protease 34;+++[A0A0C4DG73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000410559}; Flags: Fragment;+++[H7BZ73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000388129}; Flags: Fragment;+++[H7C150_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398489}; Flags: Fragment;+++[H7C183_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398960}; Flags: Fragment;"]
[9737,"'GPRASP1'",94,95,83,90.6666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0008333///endosome to lysosome transport+++GO:1990172///G protein-coupled receptor catabolic process","G protein-coupled receptor associated sorting protein 1","[GASP1_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 1; Short=GASP-1;"]
[9738,"'CCP110'",138,133,116,129,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0030030///cell projection organization+++GO:0032465///regulation of cytokinesis+++GO:0007099///centriole replication+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0045724///positive regulation of cilium assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1902018///negative regulation of cilium assembly+++GO:0016579///protein deubiquitination+++GO:0051298///centrosome duplication+++GO:0032053///ciliary basal body organization","centriolar coiled-coil protein 110","[CP110_HUMAN|Reviewed]RecName: Full=Centriolar coiled-coil protein of 110 kDa; AltName: Full=Centrosomal protein of 110 kDa; Short=CP110; Short=Cep110;+++[A0A024QYV8_HUMAN|Unreviewed]SubName: Full=CP110 protein, isoform CRA_a {ECO:0000313|EMBL:EAW50288.1};+++[H3BMS1_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000454514}; Flags: Fragment;+++[H3BVH3_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000458123};+++[I3L262_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000459410}; Flags: Fragment;"]
[9739,"'SETD1A'",1247,1414,1303,1321.33333333333,"00310///Lysine degradation",null,null,"R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine","GO:0048188///Set1C/COMPASS complex+++GO:0016607///nuclear speck+++GO:0000790///nuclear chromatin+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0016740///transferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008013///beta-catenin binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008134///transcription factor binding","GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0032259///methylation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:1902275///regulation of chromatin organization+++GO:0051568///histone H3-K4 methylation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization","SET domain containing 1A","[SET1A_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETD1A; EC=2.1.1.43; AltName: Full=Lysine N-methyltransferase 2F; AltName: Full=SET domain-containing protein 1A; Short=hSET1A; AltName: Full=Set1/Ash2 histone methyltransferase complex subunit SET1;+++[C9J2Z9_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETD1A {ECO:0000313|Ensembl:ENSP00000391408}; Flags: Fragment;+++[L0R6N9_HUMAN|Unreviewed]SubName: Full=Alternative protein SETD1A {ECO:0000313|EMBL:CCO13810.1};"]
[974,"'CD79B'",5,4,7,5.33333333333333,"04662///B cell receptor signaling pathway","H00085///Agammaglobulinemias",null,null,"GO:0009897///external side of plasma membrane+++GO:0019815///B cell receptor complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0004888///transmembrane signaling receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0002376///immune system process+++GO:0051260///protein homooligomerization+++GO:0050853///B cell receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0002250///adaptive immune response","CD79b molecule","[CD79B_HUMAN|Reviewed]RecName: Full=B-cell antigen receptor complex-associated protein beta chain; AltName: Full=B-cell-specific glycoprotein B29; AltName: Full=Ig-beta; AltName: Full=Immunoglobulin-associated B29 protein; AltName: CD_antigen=CD79b; Flags: Precursor;+++[A0A192GQF2_HUMAN|Unreviewed]SubName: Full=B-cell antigen receptor complex-associated protein beta chain isoform 3 {ECO:0000313|EMBL:ANK58153.1}; Flags: Fragment;+++[Q6PIS4_HUMAN|Unreviewed]SubName: Full=CD79B protein {ECO:0000313|EMBL:AAH30210.1};"]
[9741,"'LAPTM4A'",3852,2930,3389,3390.33333333333,"04142///Lysosome",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding",null,"lysosomal protein transmembrane 4 alpha","[LAP4A_HUMAN|Reviewed]RecName: Full=Lysosomal-associated transmembrane protein 4A; AltName: Full=Golgi 4-transmembrane-spanning transporter MTP;+++[Q4ZG00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAX88938.1}; Flags: Fragment;+++[Q53QZ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAY24172.1}; Flags: Fragment;+++[Q6IBP4_HUMAN|Unreviewed]SubName: Full=LAPTM4A protein {ECO:0000313|EMBL:CAG33039.1}; SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH93075.1}; SubName: Full=Lysosomal-associated protein transmembrane 4 alpha, isoform CRA_b {ECO:0000313|EMBL:EAX00834.1};+++[Q9BTU8_HUMAN|Unreviewed]SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH03158.1};"]
[9742,"'IFT140'",798,933,811,847.333333333333,null,"H02157///Short-rib thoracic dysplasia",null,null,"GO:0005737///cytoplasm+++GO:0097730///non-motile cilium+++GO:0005929///cilium+++GO:0097542///ciliary tip+++GO:0036064///ciliary basal body+++GO:0030991///intraciliary transport particle A+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0032391///photoreceptor connecting cilium+++GO:0005930///axoneme+++GO:0001750///photoreceptor outer segment+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0003674///molecular_function","GO:0035721///intraciliary retrograde transport+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1990403///embryonic brain development+++GO:0035108///limb morphogenesis+++GO:0008589///regulation of smoothened signaling pathway+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0021532///neural tube patterning+++GO:0007368///determination of left/right symmetry+++GO:1905515///non-motile cilium assembly+++GO:0048705///skeletal system morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0035845///photoreceptor cell outer segment organization+++GO:1902017///regulation of cilium assembly+++GO:0030030///cell projection organization+++GO:0042733///embryonic digit morphogenesis+++GO:0060041///retina development in camera-type eye+++GO:0007507///heart development+++GO:0031076///embryonic camera-type eye development+++GO:0072001///renal system development","intraflagellar transport 140","[IF140_HUMAN|Reviewed]RecName: Full=Intraflagellar transport protein 140 homolog; AltName: Full=WD and tetratricopeptide repeats protein 2;+++[H3BNC5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000454781}; Flags: Fragment;+++[H3BTA5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000457092}; Flags: Fragment;+++[I3L0Y8_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000458439}; Flags: Fragment;+++[J3KPW0_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000380562};+++[Q96RY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein gs114 {ECO:0000313|EMBL:AAK61287.1};"]
[9743,"'ARHGAP32'",412,496,408,438.666666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0015629///actin cytoskeleton+++GO:0005783///endoplasmic reticulum+++GO:0014069///postsynaptic density+++GO:0005789///endoplasmic reticulum membrane+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0001650///fibrillar center","GO:0035091///phosphatidylinositol binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 32","[RHG32_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 32; AltName: Full=Brain-specific Rho GTPase-activating protein; AltName: Full=GAB-associated Cdc42/Rac GTPase-activating protein; AltName: Full=GC-GAP; AltName: Full=GTPase regulator interacting with TrkA; AltName: Full=Rho-type GTPase-activating protein 32; AltName: Full=Rho/Cdc42/Rac GTPase-activating protein RICS; AltName: Full=RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; AltName: Full=p200RhoGAP; AltName: Full=p250GAP;+++[A0A024R3K8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_c {ECO:0000313|EMBL:EAW67737.1};+++[A0A024R3N1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_a {ECO:0000313|EMBL:EAW67733.1};+++[A0A2X0SFD0_HUMAN|Unreviewed]SubName: Full=ARHGAP32 {ECO:0000313|EMBL:SPT35703.1}; Flags: Fragment;+++[E9PRH3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432303}; Flags: Fragment;+++[G3V174_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432468}; SubName: Full=Rho GTPase-activating protein, isoform CRA_b {ECO:0000313|EMBL:EAW67734.1};+++[Q86T64_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451F1115 {ECO:0000313|EMBL:CAD89974.1}; Flags: Fragment;+++[Q86UT2_HUMAN|Unreviewed]SubName: Full=RICS protein {ECO:0000313|EMBL:AAH51236.1}; Flags: Fragment;"]
[9744,"'ACAP1'",45.54,33.47,51.38,43.4633333333333,"04144///Endocytosis",{"$nulls":3},"GO:0055038///recycling endosome membrane+++GO:0005768///endosome+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity+++GO:0015031///protein transport","ArfGAP with coiled-coil, ankyrin repeat and PH domains 1","[ACAP1_HUMAN|Reviewed]RecName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; AltName: Full=Centaurin-beta-1; Short=Cnt-b1;+++[I3L0K9_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000458173}; Flags: Fragment;+++[I3L268_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459422}; Flags: Fragment;"]
[9745,"'ZNF536'",279,394,322,331.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0045665///negative regulation of neuron differentiation+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger protein 536","[ZN536_HUMAN|Reviewed]RecName: Full=Zinc finger protein 536;+++[A7E228_HUMAN|Unreviewed]SubName: Full=ZNF536 protein {ECO:0000313|EMBL:AAI50172.1};+++[K7EJP8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465268}; Flags: Fragment;+++[K7EKT4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465771}; Flags: Fragment;+++[K7EQN6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000467909}; Flags: Fragment;"]
[9746,"'CLSTN3'",3699,3881,3684,3754.66666666667,{"$nulls":4},"GO:0099061///integral component of postsynaptic density membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0098982///GABA-ergic synapse+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0098978///glutamatergic synapse+++GO:0014069///postsynaptic density","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051965///positive regulation of synapse assembly+++GO:0051932///synaptic transmission, GABAergic+++GO:1905606///regulation of presynapse assembly+++GO:0001558///regulation of cell growth+++GO:0050806///positive regulation of synaptic transmission+++GO:1902474///positive regulation of protein localization to synapse+++GO:0007155///cell adhesion+++GO:0007416///synapse assembly+++GO:0035249///synaptic transmission, glutamatergic","calsyntenin 3","[CSTN3_HUMAN|Reviewed]RecName: Full=Calsyntenin-3; AltName: Full=Alcadein-beta; Short=Alc-beta; Flags: Precursor;+++[F5H172_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443959}; Flags: Fragment;+++[F5H5C6_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443490}; Flags: Fragment;+++[F5H5D7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443468}; Flags: Fragment;+++[F5H746_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442801}; Flags: Fragment;+++[F5H7C7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442612}; Flags: Fragment;+++[Q8IUW6_HUMAN|Unreviewed]SubName: Full=CLSTN3 protein {ECO:0000313|EMBL:AAH39075.1};"]
[9747,"'TCAF1'",1885,1796,1680,1787,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0044325///ion channel binding","GO:1901529///positive regulation of anion channel activity+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0030336///negative regulation of cell migration","TRPM8 channel associated factor 1","[TCAF1_HUMAN|Reviewed]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[B4DST7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58406, weakly similar to Mus musculus experimental autoimmune prostatitis antigen 2 (Eapa2), mRNA {ECO:0000313|EMBL:BAG61749.1};+++[C9J648_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000418432}; Flags: Fragment;+++[C9J9F4_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000417600}; Flags: Fragment;+++[C9JD13_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000420607}; Flags: Fragment;+++[C9K0E7_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000419622}; Flags: Fragment;"]
[9748,"'SLK'",1415,1702,1487,1534.66666666667,"04114///Oocyte meiosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0031252///cell leading edge","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0042802///identical protein binding","GO:0030334///regulation of cell migration+++GO:0023014///signal transduction by protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031122///cytoplasmic microtubule organization+++GO:0006915///apoptotic process+++GO:0051893///regulation of focal adhesion assembly+++GO:0007346///regulation of mitotic cell cycle+++GO:0032147///activation of protein kinase activity","STE20 like kinase","[SLK_HUMAN|Reviewed]RecName: Full=STE20-like serine/threonine-protein kinase; Short=STE20-like kinase; Short=hSLK; EC=2.7.11.1; AltName: Full=CTCL tumor antigen se20-9; AltName: Full=STE20-related serine/threonine-protein kinase; Short=STE20-related kinase; AltName: Full=Serine/threonine-protein kinase 2;+++[L8ECF1_HUMAN|Unreviewed]SubName: Full=Alternative protein SLK {ECO:0000313|EMBL:CCQ43457.1};"]
[9749,"'PHACTR2'",885,935.8,849,889.933333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031092///platelet alpha granule membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0004864///protein phosphatase inhibitor activity","GO:0002576///platelet degranulation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","phosphatase and actin regulator 2","[PHAR2_HUMAN|Reviewed]RecName: Full=Phosphatase and actin regulator 2;+++[F5H858_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[F6TH74_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[H9KVA6_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};+++[J3KP75_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};"]
[975,"'CD81'",9231,7841,7972,8348,"05144///Malaria+++04662///B cell receptor signaling pathway+++05160///Hepatitis C","H00088///Common variable immunodeficiency (CVID)",null,null,"GO:0001772///immunological synapse+++GO:0031982///vesicle+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005925///focal adhesion","GO:0001618///virus receptor activity+++GO:0023026///MHC class II protein complex binding+++GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:1990459///transferrin receptor binding","GO:0008284///positive regulation of cell proliferation+++GO:0046718///viral entry into host cell+++GO:0061462///protein localization to lysosome+++GO:0031647///regulation of protein stability+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000145///regulation of cell motility+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:0008104///protein localization+++GO:0050776///regulation of immune response+++GO:0030449///regulation of complement activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000187///activation of MAPK activity+++GO:0031623///receptor internalization+++GO:0008283///cell proliferation+++GO:0016032///viral process+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0043128///positive regulation of 1-phosphatidylinositol 4-kinase activity+++GO:0030890///positive regulation of B cell proliferation+++GO:1904352///positive regulation of protein catabolic process in the vacuole+++GO:0007166///cell surface receptor signaling pathway","CD81 molecule","[CD81_HUMAN|Reviewed]RecName: Full=CD81 antigen; AltName: Full=26 kDa cell surface protein TAPA-1; AltName: Full=Target of the antiproliferative antibody 1; AltName: Full=Tetraspanin-28; Short=Tspan-28; AltName: CD_antigen=CD81;+++[A0A024RCB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[A6NMH8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PIF1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJK1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PM31_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000433178}; Flags: Fragment;+++[E9PPF5_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432723}; Flags: Fragment;+++[E9PQV4_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432497}; Flags: Fragment;+++[E9PRJ8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDJ9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDL9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YEE2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[9750,"'RIPOR2'",9,3,6,6,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0060171///stereocilium membrane+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0032420///stereocilium","GO:0071889///14-3-3 protein binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0071158///positive regulation of cell cycle arrest+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0007605///sensory perception of sound+++GO:1903904///negative regulation of establishment of T cell polarity+++GO:0071260///cellular response to mechanical stimulus+++GO:2000405///negative regulation of T cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0051491///positive regulation of filopodium assembly+++GO:0045663///positive regulation of myoblast differentiation+++GO:0006935///chemotaxis+++GO:1905872///negative regulation of protein localization to cell leading edge+++GO:0042130///negative regulation of T cell proliferation+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:2001107///negative regulation of Rho guanyl-nucleotide exchange factor activity+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0009968///negative regulation of signal transduction+++GO:0048741///skeletal muscle fiber development+++GO:1901741///positive regulation of myoblast fusion+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0030154///cell differentiation+++GO:0045184///establishment of protein localization+++GO:2000114///regulation of establishment of cell polarity+++GO:1990869///cellular response to chemokine+++GO:0051260///protein homooligomerization+++GO:1901673///regulation of mitotic spindle assembly+++GO:0090023///positive regulation of neutrophil chemotaxis","RHO family interacting cell polarization regulator 2","[RIPR2_HUMAN|Reviewed]RecName: Full=Rho family-interacting cell polarization regulator 2;+++[A0A024QZY9_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_c {ECO:0000313|EMBL:EAW55471.1};+++[A0A024R028_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_a {ECO:0000313|EMBL:EAW55469.1};+++[A0A2R8Y4B9_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493881}; Flags: Fragment;+++[A0A2R8Y4N2_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493948}; Flags: Fragment;+++[A0A2R8Y7B3_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000495879};+++[A0A2R8YEE0_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494268};+++[A0A2R8YF77_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494904};+++[B7Z5J9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56137 {ECO:0000313|EMBL:BAH12935.1};+++[B7Z6D6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60883 {ECO:0000313|EMBL:BAH13222.1};+++[B7Z6U4_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441305}; SubName: Full=cDNA FLJ56038 {ECO:0000313|EMBL:BAH13380.1};+++[F5GX51_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441138};+++[F5H029_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000438425};"]
[9751,"'SNPH'",132,105,106,114.333333333333,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0005881///cytoplasmic microtubule+++GO:0042734///presynaptic membrane+++GO:0016021///integral component of membrane","GO:0017075///syntaxin-1 binding","GO:0016081///synaptic vesicle docking+++GO:0007269///neurotransmitter secretion+++GO:0030182///neuron differentiation+++GO:0007420///brain development","syntaphilin","[SNPH_HUMAN|Reviewed]RecName: Full=Syntaphilin;"]
[9752,"'PCDHA9'",2.32,0,2.76,1.69333333333333,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","protocadherin alpha 9","[PCDA9_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-9; Short=PCDH-alpha-9; Flags: Precursor;"]
[9753,"'ZSCAN12'",179,189,149.02,172.34,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and SCAN domain containing 12","[ZSC12_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 12; AltName: Full=Zinc finger protein 305; AltName: Full=Zinc finger protein 96;+++[A0A024RCI2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 96, isoform CRA_a {ECO:0000313|EMBL:EAX03162.1};"]
[9754,"'STARD8'",67,119,105,97,{"$nulls":4},"GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0008289///lipid binding","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity","StAR related lipid transfer domain containing 8","[STAR8_HUMAN|Reviewed]RecName: Full=StAR-related lipid transfer protein 8; AltName: Full=Deleted in liver cancer 3 protein; Short=DLC-3; AltName: Full=START domain-containing protein 8; Short=StARD8; AltName: Full=START-GAP3;+++[A0A2X0U2P1_HUMAN|Unreviewed]SubName: Full=STARD8 {ECO:0000313|EMBL:SPT35801.1}; Flags: Fragment;+++[E5RFN7_HUMAN|Unreviewed]SubName: Full=StAR-related lipid transfer protein 8 {ECO:0000313|Ensembl:ENSP00000428031};"]
[9755,"'TBKBP1'",613,767,635,671.666666666667,"04622///RIG-I-like receptor signaling pathway",{"$nulls":4},"GO:0005515///protein binding","GO:0002376///immune system process+++GO:0016032///viral process+++GO:0045087///innate immune response","TBK1 binding protein 1","[TBKB1_HUMAN|Reviewed]RecName: Full=TANK-binding kinase 1-binding protein 1; Short=TBK1-binding protein 1;+++[D3DTT5_HUMAN|Unreviewed]SubName: Full=TBK1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94806.1};+++[F5H1U4_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000446365}; Flags: Fragment;+++[J3KS71_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000462339}; Flags: Fragment;"]
[9757,"'KMT2B'",1274,1565,1399,1412.66666666667,"00310///Lysine degradation","H01613///Follicular lymphoma+++H00831///Primary dystonia",null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008168///methyltransferase activity","GO:0051568///histone H3-K4 methylation+++GO:0032259///methylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0009994///oocyte differentiation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization+++GO:0016458///gene silencing+++GO:0007613///memory+++GO:0080182///histone H3-K4 trimethylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0030728///ovulation","lysine methyltransferase 2B","[KMT2B_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase 2B; Short=Lysine N-methyltransferase 2B; EC=2.1.1.43; AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 4; AltName: Full=Trithorax homolog 2; AltName: Full=WW domain-binding protein 7; Short=WBP-7;"]
[9758,"'FRMPD4'",2,1,6,3,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine","GO:0008289///lipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005515///protein binding","GO:0051835///positive regulation of synapse structural plasticity+++GO:0098974///postsynaptic actin cytoskeleton organization","FERM and PDZ domain containing 4","[FRPD4_HUMAN|Reviewed]RecName: Full=FERM and PDZ domain-containing protein 4; AltName: Full=PDZ domain-containing protein 10; AltName: Full=PSD-95-interacting regulator of spine morphogenesis; Short=Preso;+++[A0A087WYX8_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000482182};+++[A0A1W2PQW0_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000492353}; Flags: Fragment;+++[B7ZLE1_HUMAN|Unreviewed]SubName: Full=FRMPD4 protein {ECO:0000313|EMBL:AAI43747.1};"]
[9759,"'HDAC4'",173,207,183,187.666666666667,"05203///Viral carcinogenesis+++05034///Alcoholism+++05169///Epstein-Barr virus infection+++05165///Human papillomavirus infection+++04371///Apelin signaling pathway","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0017053///transcriptional repressor complex+++GO:0005654///nucleoplasm+++GO:0042641///actomyosin+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0031672///A band+++GO:0030018///Z disc+++GO:0031594///neuromuscular junction+++GO:0030017///sarcomere+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:1990841///promoter-specific chromatin binding+++GO:0004407///histone deacetylase activity+++GO:0042826///histone deacetylase binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033613///activating transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0008270///zinc ion binding+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0030955///potassium ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003714///transcription corepressor activity+++GO:0070491///repressing transcription factor binding+++GO:0033558///protein deacetylase activity+++GO:0005515///protein binding+++GO:0001085///RNA polymerase II transcription factor binding","GO:0006954///inflammatory response+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0040029///regulation of gene expression, epigenetic+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0033235///positive regulation of protein sumoylation+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0030183///B cell differentiation+++GO:0006338///chromatin remodeling+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070555///response to interleukin-1+++GO:0008284///positive regulation of cell proliferation+++GO:0001501///skeletal system development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0002076///osteoblast development+++GO:0006476///protein deacetylation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0042113///B cell activation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0007399///nervous system development+++GO:0045820///negative regulation of glycolytic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0043393///regulation of protein binding+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0016575///histone deacetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0006325///chromatin organization+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010832///negative regulation of myotube differentiation","histone deacetylase 4","[HDAC4_HUMAN|Reviewed]RecName: Full=Histone deacetylase 4; Short=HD4; EC=3.5.1.98;+++[C9J0X4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000392912}; Flags: Fragment;+++[C9J481_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000405226}; Flags: Fragment;+++[F5H0B1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000438111}; Flags: Fragment;+++[H7BZT3_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000391226}; Flags: Fragment;+++[H7C397_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000410551}; Flags: Fragment;"]
[976,"'ADGRE5'",176,205,175,185.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0030667///secretory granule membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007267///cell-cell signaling+++GO:0007155///cell adhesion+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0043312///neutrophil degranulation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor E5","[CD97_HUMAN|Reviewed]RecName: Full=CD97 antigen; AltName: Full=Leukocyte antigen CD97; AltName: CD_antigen=CD97; Contains: RecName: Full=CD97 antigen subunit alpha; Contains: RecName: Full=CD97 antigen subunit beta; Flags: Precursor;+++[K7EKV5_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000465800}; Flags: Fragment;+++[K7EPE8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467351}; Flags: Fragment;+++[K7EPP8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467478}; Flags: Fragment;"]
[9760,"'TOX'",580,574,596,583.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0048535///lymph node development+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030098///lymphocyte differentiation+++GO:0048541///Peyer's patch development","thymocyte selection associated high mobility group box","[TOX_HUMAN|Reviewed]RecName: Full=Thymocyte selection-associated high mobility group box protein TOX; AltName: Full=Thymus high mobility group box protein TOX;"]
[9761,"'MLEC'",3449,3294,3276,3339.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0035579///specific granule membrane+++GO:0005886///plasma membrane","GO:0019899///enzyme binding+++GO:0030246///carbohydrate binding","GO:0005975///carbohydrate metabolic process+++GO:0043312///neutrophil degranulation+++GO:0006457///protein folding","malectin","[MLEC_HUMAN|Reviewed]RecName: Full=Malectin; Flags: Precursor;+++[F5GX14_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000440746};+++[F5H1S8_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000438950}; Flags: Fragment;+++[H0YG07_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000441247}; Flags: Fragment;"]
[9762,"'LZTS3'",186,171,166,174.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density",null,"GO:0061001///regulation of dendritic spine morphogenesis","leucine zipper tumor suppressor family member 3","[LZTS3_HUMAN|Reviewed]RecName: Full=Leucine zipper putative tumor suppressor 3 {ECO:0000305}; AltName: Full=ProSAP-interacting protein 1 {ECO:0000250|UniProtKB:Q8K1Q4}; Short=ProSAPiP1 {ECO:0000250|UniProtKB:Q8K1Q4};"]
[9764,"'KIAA0513'",270,281,264,271.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm",null,null,"KIAA0513","[K0513_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0513;+++[H3BMU3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454547}; Flags: Fragment;+++[H3BNA7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454758}; Flags: Fragment;"]
[9765,"'ZFYVE16'",242,278,254,258,"04350///TGF-beta signaling pathway+++04144///Endocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm","GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0046872///metal ion binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding","GO:0016050///vesicle organization+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0030509///BMP signaling pathway+++GO:0016197///endosomal transport+++GO:0006622///protein targeting to lysosome","zinc finger FYVE-type containing 16","[ZFY16_HUMAN|Reviewed]RecName: Full=Zinc finger FYVE domain-containing protein 16; AltName: Full=Endofin; AltName: Full=Endosome-associated FYVE domain protein;+++[A0A024RAL3_HUMAN|Unreviewed]RecName: Full=Zinc finger FYVE domain-containing protein {ECO:0000256|PIRNR:PIRNR037289};+++[D6RC80_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000422356}; Flags: Fragment;+++[H0Y8R0_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000421785}; Flags: Fragment;+++[H0YAA4_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426500}; Flags: Fragment;+++[H0YAB1_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426536}; Flags: Fragment;"]
[9766,"'SUSD6'",404,379,347,376.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0008219///cell death","sushi domain containing 6","[SUSD6_HUMAN|Reviewed]RecName: Full=Sushi domain-containing protein 6 {ECO:0000312|HGNC:HGNC:19956}; AltName: Full=Drug-activated gene overexpressed protein {ECO:0000303|PubMed:24652652}; Flags: Precursor;"]
[9767,"'JADE3'",80,80,92,84,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000123///histone acetyltransferase complex","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0043981///histone H4-K5 acetylation+++GO:0043966///histone H3 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0043982///histone H4-K8 acetylation","jade family PHD finger 3","[JADE3_HUMAN|Reviewed]RecName: Full=Protein Jade-3; AltName: Full=Jade family PHD finger protein 3; AltName: Full=PHD finger protein 16;+++[A0A024R1A2_HUMAN|Unreviewed]SubName: Full=PHD finger protein 16, isoform CRA_a {ECO:0000313|EMBL:EAW59278.1};+++[F2Z2B6_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000400584}; Flags: Fragment;+++[F2Z3N8_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000391009}; Flags: Fragment;"]
[9768,"'PCLAF'",5.03,7.19,1.02,4.41333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0003682///chromatin binding","GO:0006260///DNA replication+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0007098///centrosome cycle+++GO:0006281///DNA repair+++GO:0019985///translesion synthesis","PCNA clamp associated factor","[PAF15_HUMAN|Reviewed]RecName: Full=PCNA-associated factor {ECO:0000305}; AltName: Full=Hepatitis C virus NS5A-transactivated protein 9; Short=HCV NS5A-transactivated protein 9; AltName: Full=Overexpressed in anaplastic thyroid carcinoma 1; Short=OEATC-1; AltName: Full=PCNA-associated factor of 15 kDa; Short=PAF15; Short=p15PAF; AltName: Full=PCNA-clamp-associated factor {ECO:0000312|HGNC:HGNC:28961};+++[G9G6C4_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89543.1}; Flags: Fragment;+++[G9G6D7_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89556.1}; Flags: Fragment;+++[G9G6H1_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89590.1}; Flags: Fragment;+++[H0YKX3_HUMAN|Unreviewed]SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000452975};+++[H0YMA4_HUMAN|Unreviewed]SubName: Full=HCG2039386, isoform CRA_b {ECO:0000313|EMBL:EAW77680.1}; SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000453527};"]
[977,"'CD151'",10539,8996,9253,9596,null,"H00928///Nephropathy with pretibial epidermolysis bullosa and deafness",null,null,"GO:0009986///cell surface+++GO:0005925///focal adhesion+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005604///basement membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005178///integrin binding","GO:0044319///wound healing, spreading of cells+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0031581///hemidesmosome assembly+++GO:0016477///cell migration+++GO:0045807///positive regulation of endocytosis+++GO:0030335///positive regulation of cell migration+++GO:0042098///T cell proliferation","CD151 molecule (Raph blood group)","[CD151_HUMAN|Reviewed]RecName: Full=CD151 antigen; AltName: Full=GP27; AltName: Full=Membrane glycoprotein SFA-1; AltName: Full=Platelet-endothelial tetraspan antigen 3; Short=PETA-3; AltName: Full=Tetraspanin-24; Short=Tspan-24; AltName: CD_antigen=CD151;+++[A0A024RCB3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJC8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PJE8_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000433752}; Flags: Fragment;+++[E9PK37_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000431671}; Flags: Fragment;+++[E9PLZ6_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PMR4_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PP93_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000434663}; Flags: Fragment;+++[E9PRJ3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PSA1_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000435854}; Flags: Fragment;+++[K4DIA7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[K4DIB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[Q6ZNZ0_HUMAN|Unreviewed]SubName: Full=CD151 antigen (Raph blood group), isoform CRA_b {ECO:0000313|EMBL:EAX02401.1}; SubName: Full=cDNA FLJ26859 fis, clone PRS08290 {ECO:0000313|EMBL:BAC85335.1};"]
[9770,"'RASSF2'",700,646,581,642.333333333333,"04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species",{"$nulls":3},"GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0000777///condensed chromosome kinetochore","GO:0004672///protein kinase activity+++GO:0005515///protein binding","GO:0038168///epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade+++GO:0001501///skeletal system development+++GO:0042981///regulation of apoptotic process+++GO:0046849///bone remodeling+++GO:0045670///regulation of osteoclast differentiation+++GO:0001503///ossification+++GO:0050821///protein stabilization+++GO:0046330///positive regulation of JNK cascade+++GO:0007049///cell cycle+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:0048872///homeostasis of number of cells+++GO:0006468///protein phosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0045667///regulation of osteoblast differentiation+++GO:0007165///signal transduction+++GO:0043065///positive regulation of apoptotic process","Ras association domain family member 2","[RASF2_HUMAN|Reviewed]RecName: Full=Ras association domain-containing protein 2;"]
[9771,"'RAPGEF5'",88,81,76,81.6666666666667,"04015///Rap1 signaling pathway+++04014///Ras signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0030742///GTP-dependent protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0017034///Rap guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0035556///intracellular signal transduction+++GO:0007399///nervous system development+++GO:0007264///small GTPase mediated signal transduction","Rap guanine nucleotide exchange factor 5","[RPGF5_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 5; AltName: Full=Guanine nucleotide exchange factor for Rap1; AltName: Full=M-Ras-regulated Rap GEF; Short=MR-GEF; AltName: Full=Related to Epac; Short=Repac;+++[A0A0S2Z561_HUMAN|Unreviewed]SubName: Full=HCG38228, isoform CRA_b {ECO:0000313|EMBL:EAW93746.1}; SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 2 {ECO:0000313|EMBL:ALQ33949.1}; Flags: Fragment;+++[A0A0S2Z5S1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 1 {ECO:0000313|EMBL:ALQ33948.1}; Flags: Fragment;+++[A8MQ07_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000343656};+++[C9JBS6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000415664}; Flags: Fragment;+++[C9JHM4_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000395729}; Flags: Fragment;+++[E9PGY3_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000384870};+++[F8WD32_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000403956};+++[Q5JPD2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667A016 {ECO:0000313|EMBL:CAI46177.1};"]
[9772,"'TMEM94'",3005,3456,2928,3129.66666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 94","[TMM94_HUMAN|Reviewed]RecName: Full=Transmembrane protein 94 {ECO:0000312|HGNC:HGNC:28983};+++[A0A024R8S6_HUMAN|Unreviewed]SubName: Full=KIAA0195, isoform CRA_a {ECO:0000313|EMBL:EAW89275.1};+++[B7Z9U5_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78959, highly similar to Transmembrane protein 94 {ECO:0000313|EMBL:BAH14431.1};+++[C9JL75_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000364397};+++[J3KRN3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462084}; Flags: Fragment;+++[J3KRU7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462170}; Flags: Fragment;+++[J3KS76_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462344};+++[J3KT63_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462821}; Flags: Fragment;+++[J3KTL5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463046}; Flags: Fragment;+++[J3QLC5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463487}; Flags: Fragment;+++[J3QLM7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463620}; Flags: Fragment;+++[J3QQW3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463929};+++[J3QRT3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464370}; Flags: Fragment;+++[J3QRT7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464375}; Flags: Fragment;+++[J3QRY7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464437}; Flags: Fragment;+++[J3QS17_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464479}; Flags: Fragment;+++[J3QS24_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464491}; Flags: Fragment;+++[J3QSG7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464679}; Flags: Fragment;"]
[9774,"'BCLAF1'",1885,1894,1694,1824.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:1990830///cellular response to leukemia inhibitory factor+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0043065///positive regulation of apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006915///apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2001022///positive regulation of response to DNA damage stimulus","BCL2 associated transcription factor 1","[BCLF1_HUMAN|Reviewed]RecName: Full=Bcl-2-associated transcription factor 1; Short=Btf; AltName: Full=BCLAF1 and THRAP3 family member 1;+++[A0A1W2PQ43_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000491530};+++[E9PJA7_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433822};+++[E9PK09_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000431734}; Flags: Fragment;+++[E9PK91_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000435441};+++[E9PKI6_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433505};+++[E9PQN2_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436142};+++[H0YF00_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436913}; Flags: Fragment;+++[H0YF14_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437018}; Flags: Fragment;+++[H0YF63_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437333}; Flags: Fragment;+++[Q6DCA8_HUMAN|Unreviewed]SubName: Full=BCLAF1 protein {ECO:0000313|EMBL:AAH78160.1}; Flags: Fragment;"]
[9775,"'EIF4A3'",474,488,466,476,"03013///RNA transport+++03015///mRNA surveillance pathway+++03040///Spliceosome",null,"M00430///Exon junction complex (EJC)",null,"GO:0016607///nuclear speck+++GO:1990904///ribonucleoprotein complex+++GO:0043025///neuronal cell body+++GO:0071013///catalytic step 2 spliceosome+++GO:0099524///postsynaptic cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex+++GO:0005681///spliceosomal complex+++GO:0030425///dendrite+++GO:0005634///nucleus","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0008143///poly(A) binding+++GO:0003729///mRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0000166///nucleotide binding","GO:0006364///rRNA processing+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0072715///cellular response to selenite ion+++GO:0035640///exploration behavior+++GO:1902415///regulation of mRNA binding+++GO:0045727///positive regulation of translation+++GO:1904570///negative regulation of selenocysteine incorporation+++GO:0008306///associative learning+++GO:0006406///mRNA export from nucleus+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:1904574///negative regulation of selenocysteine insertion sequence binding+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0008380///RNA splicing+++GO:0031124///mRNA 3'-end processing+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0014070///response to organic cyclic compound+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0010629///negative regulation of gene expression+++GO:0051028///mRNA transport","eukaryotic translation initiation factor 4A3","[IF4A3_HUMAN|Reviewed]RecName: Full=Eukaryotic initiation factor 4A-III; Short=eIF-4A-III; Short=eIF4A-III; EC=3.6.4.13 {ECO:0000269|PubMed:16170325, ECO:0000269|PubMed:17375189, ECO:0000269|PubMed:22961380}; AltName: Full=ATP-dependent RNA helicase DDX48; AltName: Full=ATP-dependent RNA helicase eIF4A-3; AltName: Full=DEAD box protein 48; AltName: Full=Eukaryotic initiation factor 4A-like NUK-34; AltName: Full=Eukaryotic translation initiation factor 4A isoform 3; AltName: Full=Nuclear matrix protein 265; Short=NMP 265; Short=hNMP 265; Contains: RecName: Full=Eukaryotic initiation factor 4A-III, N-terminally processed;+++[A0A024R8W0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 48, isoform CRA_a {ECO:0000313|EMBL:EAW89585.1};+++[I3L3H2_HUMAN|Unreviewed]SubName: Full=Eukaryotic initiation factor 4A-III {ECO:0000313|Ensembl:ENSP00000460439}; Flags: Fragment;"]
[9776,"'ATG13'",2186,2150,2204,2180,"04138///Autophagy - yeast+++04136///Autophagy - other+++04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0019898///extrinsic component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane","GO:0019887///protein kinase regulator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0098780///response to mitochondrial depolarisation+++GO:0000422///autophagy of mitochondrion+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0000045///autophagosome assembly+++GO:0016241///regulation of macroautophagy+++GO:0006914///autophagy+++GO:0000423///mitophagy+++GO:0034497///protein localization to phagophore assembly site+++GO:0032147///activation of protein kinase activity+++GO:0016236///macroautophagy","autophagy related 13","[ATG13_HUMAN|Reviewed]RecName: Full=Autophagy-related protein 13;+++[A0A1B0GXJ3_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463808}; Flags: Fragment;+++[A8K0S6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214};+++[E9PPR2_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;+++[H0YCL5_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000431877}; Flags: Fragment;+++[H0YDR0_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000434125}; Flags: Fragment;+++[H0YEM7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000436174}; Flags: Fragment;+++[H0YF43_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000437191}; Flags: Fragment;+++[J3KRU6_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462167}; Flags: Fragment;+++[J3KST9_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462644}; Flags: Fragment;+++[J3QLH7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463550}; Flags: Fragment;+++[J3QR16_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463998}; Flags: Fragment;+++[J3QR83_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464091}; Flags: Fragment;+++[J3QRL1_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464274}; Flags: Fragment;+++[J9JIF6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;"]
[9777,"'TM9SF4'",1645,1740,1590,1658.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04062///Chemokine signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005768///endosome+++GO:0005769///early endosome","GO:0005515///protein binding","GO:0006909///phagocytosis+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0072657///protein localization to membrane+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0051453///regulation of intracellular pH+++GO:0007155///cell adhesion+++GO:0001666///response to hypoxia","transmembrane 9 superfamily member 4","[TM9S4_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 4; AltName: Full=Tumor cannibalism associated protein 1 {ECO:0000303|PubMed:19893578}; Flags: Precursor;+++[A0A024QYR3_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[A0A0C4DFM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[B4DH88_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F2Z2L1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F8WCN2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[9778,"'KIAA0232'",661,720,724,701.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0000166///nucleotide binding+++GO:0005524///ATP binding",null,"KIAA0232","[K0232_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0232;+++[A5YKK5_HUMAN|Unreviewed]SubName: Full=KIAA0232 {ECO:0000313|EMBL:ABQ66267.1};+++[D6REK0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0232 {ECO:0000313|Ensembl:ENSP00000426815};+++[Q9Y349_HUMAN|Unreviewed]SubName: Full=KIAA0232 protein {ECO:0000313|EMBL:CAG33441.1};"]
[9779,"'TBC1D5'",644,716,606,655.333333333333,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0030904///retromer complex+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:1905394///retromer complex binding","GO:0006886///intracellular protein transport+++GO:0016236///macroautophagy+++GO:1902017///regulation of cilium assembly+++GO:0002092///positive regulation of receptor internalization+++GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0006914///autophagy+++GO:0090630///activation of GTPase activity+++GO:0042594///response to starvation","TBC1 domain family member 5","[TBCD5_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 5;+++[A0A024R2H0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_a {ECO:0000313|EMBL:EAW64287.1};+++[A0A024R2J9_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_b {ECO:0000313|EMBL:EAW64288.1};+++[B9A6K1_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5 {ECO:0000313|EMBL:BAH16629.1};+++[C9J397_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000410596}; Flags: Fragment;+++[C9J3F6_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411925};+++[C9JDR8_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396239}; Flags: Fragment;+++[C9JED7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000415379}; Flags: Fragment;+++[C9JIU4_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396850}; Flags: Fragment;+++[C9JMP7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000408603}; Flags: Fragment;+++[C9JNM0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000414159}; Flags: Fragment;+++[C9JW04_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000387395}; Flags: Fragment;+++[C9JWX0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000399967}; Flags: Fragment;+++[C9K0P2_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000393882}; Flags: Fragment;+++[F2Z3C3_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000424998}; Flags: Fragment;+++[F2Z3I5_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411780};"]
[9780,"'PIEZO1'",9358,9365,8694,9139,null,"H01978///Dehydrated hereditary stomatocytosis+++H02001///Familial pseudohyperkalemia+++H00811///Distal arthrogryposis (DA)+++H00232///Hereditary stomatocytosis (HSt)",null,null,"GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0031258///lamellipodium membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane","GO:0008381///mechanosensitive ion channel activity+++GO:0005261///cation channel activity","GO:0033625///positive regulation of integrin activation+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0042391///regulation of membrane potential+++GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0050982///detection of mechanical stimulus+++GO:0006812///cation transport+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071260///cellular response to mechanical stimulus","piezo type mechanosensitive ion channel component 1","[PIEZ1_HUMAN|Reviewed]RecName: Full=Piezo-type mechanosensitive ion channel component 1; AltName: Full=Membrane protein induced by beta-amyloid treatment; Short=Mib; AltName: Full=Protein FAM38A;+++[E7EUT2_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000333704};+++[H0YB49_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000428673}; Flags: Fragment;+++[H3BRR7_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456373}; Flags: Fragment;+++[H3BSF6_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456680}; Flags: Fragment;+++[H7C2J5_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000406358}; Flags: Fragment;+++[M4QHP2_HUMAN|Unreviewed]RecName: Full=Piezo-type mechanosensitive ion channel component {ECO:0000256|RuleBase:RU362023};+++[Q96HU3_HUMAN|Unreviewed]SubName: Full=FAM38A protein {ECO:0000313|EMBL:AAH08073.2};"]
[9781,"'RNF144A'",119.21,111,104.23,111.48,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0010008///endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding","GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination","ring finger protein 144A","[R144A_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF144A; EC=2.3.2.31 {ECO:0000250|UniProtKB:O60260}; AltName: Full=RING finger protein 144A; AltName: Full=UbcM4-interacting protein 4; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 4;+++[C9JLH4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF144A {ECO:0000313|Ensembl:ENSP00000414420}; Flags: Fragment;+++[H7C3G0_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;"]
[9782,"'MATR3'",3694,3381,3162,3412.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0003676///nucleic acid binding+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0035198///miRNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0002218///activation of innate immune response+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0045087///innate immune response+++GO:0002376///immune system process","matrin 3","[MATR3_HUMAN|Reviewed]RecName: Full=Matrin-3;+++[A0A0R4J2E8_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000354346};+++[A0A1B0GX04_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421145}; Flags: Fragment;+++[A8MXP9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000378279};+++[B3KM87_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10526 fis, clone NT2RP2000931, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG50899.1};+++[B4DF66_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55637, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG57327.1};+++[D6R8Z5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422233}; Flags: Fragment;+++[D6R991_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423290}; Flags: Fragment;+++[D6R9F3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422137}; Flags: Fragment;+++[D6R9N0_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423521}; Flags: Fragment;+++[D6RAM9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421666}; Flags: Fragment;+++[D6RAY2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424646}; Flags: Fragment;+++[D6RB45_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424431}; Flags: Fragment;+++[D6RBI2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422700}; Flags: Fragment;+++[D6RBK5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422649}; Flags: Fragment;+++[D6RBS2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422590}; Flags: Fragment;+++[D6RCM3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427168};+++[D6RE02_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000425150}; Flags: Fragment;+++[D6REK4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426801}; Flags: Fragment;+++[D6REM6_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426743};+++[D6RIA2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427557}; Flags: Fragment;+++[H0Y8T4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422054}; Flags: Fragment;+++[Q68E03_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000480093};+++[Q9H4N1_HUMAN|Unreviewed]SubName: Full=Clone CDABP0107 mRNA sequence {ECO:0000313|EMBL:AAG02007.1};"]
[9783,"'RIMS3'",96,105,89,96.6666666666667,{"$nulls":4},"GO:0030054///cell junction+++GO:0016020///membrane+++GO:0042734///presynaptic membrane+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0045202///synapse+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0048786///presynaptic active zone","GO:0017137///Rab GTPase binding+++GO:0044325///ion channel binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0017156///calcium ion regulated exocytosis+++GO:0042391///regulation of membrane potential+++GO:0050806///positive regulation of synaptic transmission+++GO:0048167///regulation of synaptic plasticity+++GO:0006887///exocytosis+++GO:0006836///neurotransmitter transport+++GO:2000300///regulation of synaptic vesicle exocytosis","regulating synaptic membrane exocytosis 3","[RIMS3_HUMAN|Reviewed]RecName: Full=Regulating synaptic membrane exocytosis protein 3; Short=Nim3; AltName: Full=RIM3 gamma; AltName: Full=Rab-3-interacting molecule 3; Short=RIM 3;+++[L8EAQ2_HUMAN|Unreviewed]SubName: Full=Alternative protein RIMS3 {ECO:0000313|EMBL:CCQ43458.1};+++[X5D2V8_HUMAN|Unreviewed]SubName: Full=Regulating synaptic membrane exocytosis 3 isoform C {ECO:0000313|EMBL:AHW56609.1}; Flags: Fragment;"]
[9784,"'SNX17'",1403,1413,1357,1391,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005769///early endosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005768///endosome+++GO:0005623///cell+++GO:0010008///endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0050750///low-density lipoprotein particle receptor binding+++GO:0008289///lipid binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0035091///phosphatidylinositol binding","GO:0006898///receptor-mediated endocytosis+++GO:0016197///endosomal transport+++GO:0003279///cardiac septum development+++GO:0006707///cholesterol catabolic process+++GO:0035904///aorta development+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0015031///protein transport+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0060976///coronary vasculature development+++GO:0006886///intracellular protein transport","sorting nexin 17","[SNX17_HUMAN|Reviewed]RecName: Full=Sorting nexin-17;+++[B4DDM3_HUMAN|Unreviewed]SubName: Full=Sorting nexin 17, isoform CRA_a {ECO:0000313|EMBL:EAX00584.1}; SubName: Full=cDNA FLJ51047, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60979.1}; SubName: Full=cDNA FLJ53821, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG56784.1}; SubName: Full=cDNA FLJ61770, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG58262.1};+++[B4DQ37_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56223, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60799.1};+++[B4DTB8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51699, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG61930.1};+++[F8WAZ0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000405399};+++[F8WEG6_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000401922};+++[F8WFA0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000399727};"]
[9785,"'DHX38'",556,574,575,568.333333333333,"03040///Spliceosome",{"$nulls":3},"GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005681///spliceosomal complex","GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0006405///RNA export from nucleus","DEAH-box helicase 38","[PRP16_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase DHX38; AltName: Full=DEAH box protein 38;+++[B4DM30_HUMAN|Unreviewed]SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 38, isoform CRA_d {ECO:0000313|EMBL:EAW59183.1}; SubName: Full=cDNA FLJ50987, highly similar to Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|EMBL:BAG59742.1};+++[H3BMS7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000454521}; Flags: Fragment;+++[H3BQT9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000455939}; Flags: Fragment;+++[H3BV01_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000457887}; Flags: Fragment;+++[J3KRT1_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462149};+++[J3KSA8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462397}; Flags: Fragment;+++[J3KTG2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462965}; Flags: Fragment;"]
[9786,"'KIAA0586'",245,202,204,217,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04140///Autophagy - animal+++04137///Mitophagy - animal","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0036064///ciliary basal body+++GO:0001917///photoreceptor inner segment+++GO:0042995///cell projection+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0019904///protein domain specific binding+++GO:0043021///ribonucleoprotein complex binding+++GO:1990247///N6-methyladenosine-containing RNA binding+++GO:0004857///enzyme inhibitor activity+++GO:1990827///deaminase binding+++GO:0003729///mRNA binding","GO:0070201///regulation of establishment of protein localization+++GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly","KIAA0586","[TALD3_HUMAN|Reviewed]RecName: Full=Protein TALPID3;+++[A0A087WYM5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000481936};+++[B4DYW5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61484 {ECO:0000313|EMBL:BAG63877.1};+++[B7Z7W7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52366 {ECO:0000313|EMBL:BAH13753.1};+++[G3V2T5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000450855}; Flags: Fragment;+++[G3V4J0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451831}; Flags: Fragment;+++[G3V5U9_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000452536};+++[H0YJF0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451356}; Flags: Fragment;+++[L0R885_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0586 {ECO:0000313|EMBL:CCO13756.1};"]
[9787,"'DLGAP5'",3,2,3,2.66666666666667,{"$nulls":4},"GO:0005819///spindle+++GO:0031616///spindle pole centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0023052///signaling+++GO:0006470///protein dephosphorylation+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0008283///cell proliferation+++GO:0007221///positive regulation of transcription of Notch receptor target","DLG associated protein 5","[DLGP5_HUMAN|Reviewed]RecName: Full=Disks large-associated protein 5; Short=DAP-5; AltName: Full=Discs large homolog 7; AltName: Full=Disks large-associated protein DLG7; AltName: Full=Hepatoma up-regulated protein; Short=HURP;+++[G3V4E5_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000451747}; Flags: Fragment;+++[G3V543_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000452168};"]
[9788,"'MTSS1'",613,963,840.4,805.466666666667,"00190///Oxidative phosphorylation+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease+++01100///Metabolic pathways+++05016///Huntington's disease+++05010///Alzheimer's disease+++04714///Thermogenesis+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04723///Retrograde endocannabinoid signaling","H00473///Mitochondrial complex I deficiency","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0030139///endocytic vesicle","GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding","GO:0072160///nephron tubule epithelial cell differentiation+++GO:0072102///glomerulus morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007009///plasma membrane organization+++GO:0071498///cellular response to fluid shear stress+++GO:0030035///microspike assembly+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis+++GO:0061333///renal tubule morphogenesis","MTSS1, I-BAR domain containing","[MTSS1_HUMAN|Reviewed]RecName: Full=Metastasis suppressor protein 1; AltName: Full=Metastasis suppressor YGL-1; AltName: Full=Missing in metastasis protein;+++[A5YM41_HUMAN|Unreviewed]SubName: Full=MTSS1 protein {ECO:0000313|EMBL:ABQ59025.1};+++[E5RJX3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428145}; Flags: Fragment;+++[E7EWW5_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428319};+++[H0YAZ8_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428348}; Flags: Fragment;+++[H0YB53_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428685}; Flags: Fragment;+++[H0YBL3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000429752}; Flags: Fragment;"]
[9789,"'SPCS2'",680,611,661,650.666666666667,"03060///Protein export",null,null,"R04018///Acylneuraminyl hydrolase Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O","GO:0005787///signal peptidase complex+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0031090///organelle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005783///endoplasmic reticulum","GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0045047///protein targeting to ER","signal peptidase complex subunit 2","[SPCS2_HUMAN|Reviewed]RecName: Full=Signal peptidase complex subunit 2; EC=3.4.-.-; AltName: Full=Microsomal signal peptidase 25 kDa subunit; Short=SPase 25 kDa subunit;+++[A0A087WUC6_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000478550};+++[E9PI68_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000436759};+++[E9PL01_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000433439};+++[E9PRB9_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434248};+++[H0YE04_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434706}; Flags: Fragment;"]
[9790,"'BMS1'",719.27,753.34,671.96,714.856666666667,"03008///Ribosome biogenesis in eukaryotes","H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0030686///90S preribosome+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0034511///U3 snoRNA binding+++GO:0000166///nucleotide binding","GO:0042254///ribosome biogenesis+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","BMS1, ribosome biogenesis factor","[BMS1_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;"]
[9791,"'PTDSS1'",1099,1096,984,1059.66666666667,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways","H01832///Lenz-Majewski syndrome",null,"R07377///Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006659///phosphatidylserine biosynthetic process","phosphatidylserine synthase 1","[PTSS1_HUMAN|Reviewed]RecName: Full=Phosphatidylserine synthase 1; Short=PSS-1; Short=PtdSer synthase 1; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme I;+++[J3KNR6_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 1, isoform CRA_a {ECO:0000313|EMBL:EAW91753.1};+++[Q9BSY0_HUMAN|Unreviewed]SubName: Full=PTDSS1 protein {ECO:0000313|EMBL:AAH04502.2}; Flags: Fragment;"]
[9792,"'SERTAD2'",609,684,627,640,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003713///transcription coactivator activity","GO:0030308///negative regulation of cell growth+++GO:0045893///positive regulation of transcription, DNA-templated","SERTA domain containing 2","[SRTD2_HUMAN|Reviewed]RecName: Full=SERTA domain-containing protein 2; AltName: Full=Transcriptional regulator interacting with the PHD-bromodomain 2; Short=TRIP-Br2;"]
[9793,"'CKAP5'",1405,1552,1370,1442.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000776///kinetochore+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0000930///gamma-tubulin complex+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore+++GO:0005813///centrosome+++GO:0000922///spindle pole+++GO:0005886///plasma membrane+++GO:0005694///chromosome+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0032991///protein-containing complex+++GO:0005730///nucleolus+++GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end","GO:0051010///microtubule plus-end binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007098///centrosome cycle+++GO:0007019///microtubule depolymerization+++GO:0051301///cell division+++GO:0051298///centrosome duplication+++GO:0050658///RNA transport+++GO:0007051///spindle organization+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0046785///microtubule polymerization+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007049///cell cycle","cytoskeleton associated protein 5","[CKAP5_HUMAN|Reviewed]RecName: Full=Cytoskeleton-associated protein 5; AltName: Full=Colonic and hepatic tumor overexpressed gene protein; Short=Ch-TOG;+++[E9PQH5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436769}; Flags: Fragment;+++[H0YCF6_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000431509}; Flags: Fragment;+++[H0YDX5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000434523}; Flags: Fragment;+++[H0YEK7_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436052}; Flags: Fragment;+++[Q8IYN5_HUMAN|Unreviewed]SubName: Full=CKAP5 protein {ECO:0000313|EMBL:AAH35554.1};"]
[9794,"'MAML1'",1135,1292,1195,1207.33333333333,"04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05165///Human papillomavirus infection","H01508///Salivary gland cancer",null,null,"GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042605///peptide antigen binding+++GO:0019901///protein kinase binding","GO:0045445///myoblast differentiation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0010831///positive regulation of myotube differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0003162///atrioventricular node development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0060928///atrioventricular node cell development","mastermind like transcriptional coactivator 1","[MAML1_HUMAN|Reviewed]RecName: Full=Mastermind-like protein 1; Short=Mam-1;"]
[9796,"'PHYHIP'",131,104,120,118.333333333333,"04623///Cytosolic DNA-sensing pathway+++01100///Metabolic pathways+++04137///Mitophagy - animal+++05169///Epstein-Barr virus infection+++00230///Purine metabolism+++00240///Pyrimidine metabolism+++04140///Autophagy - animal+++03020///RNA polymerase",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA ATP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA CTP + RNA <=> Diphosphate + RNA","GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0016607///nuclear speck","GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0045089///positive regulation of innate immune response","phytanoyl-CoA 2-hydroxylase interacting protein","[PHYIP_HUMAN|Reviewed]RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein; AltName: Full=Phytanoyl-CoA hydroxylase-associated protein 1; Short=PAHX-AP1; Short=PAHXAP1;+++[E5RHN5_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA hydroxylase-interacting protein {ECO:0000313|Ensembl:ENSP00000430870}; Flags: Fragment;"]
[9797,"'TATDN2'",775,880,780,811.666666666667,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0004518///nuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters","GO:0006259///DNA metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0036498///IRE1-mediated unfolded protein response","TatD DNase domain containing 2","[TATD2_HUMAN|Reviewed]RecName: Full=Putative deoxyribonuclease TATDN2; EC=3.1.21.-;+++[A0A024R2F3_HUMAN|Unreviewed]SubName: Full=TatD DNase domain containing 2, isoform CRA_a {ECO:0000313|EMBL:EAW64071.1};+++[H7BZJ2_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN2 {ECO:0000313|Ensembl:ENSP00000389896}; Flags: Fragment;"]
[9798,"'IST1'",985,998,960,981,"04144///Endocytosis",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005737///cytoplasm+++GO:0005635///nuclear envelope+++GO:0005856///cytoskeleton+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0035578///azurophil granule lumen","GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding+++GO:0090541///MIT domain binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061640///cytoskeleton-dependent cytokinesis+++GO:0043312///neutrophil degranulation+++GO:0036258///multivesicular body assembly+++GO:1904903///ESCRT III complex disassembly+++GO:0048672///positive regulation of collateral sprouting+++GO:0051301///cell division+++GO:0019076///viral release from host cell+++GO:0045184///establishment of protein localization+++GO:0009838///abscission+++GO:0008104///protein localization+++GO:0046745///viral capsid secondary envelopment+++GO:0045862///positive regulation of proteolysis+++GO:0015031///protein transport+++GO:0007049///cell cycle","IST1, ESCRT-III associated factor","[IST1_HUMAN|Reviewed]RecName: Full=IST1 homolog; Short=hIST1; AltName: Full=Putative MAPK-activating protein PM28;+++[B4DXC9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59095 {ECO:0000313|EMBL:BAG63341.1};+++[E9PF00_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000410081};+++[F5GXM3_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000398505}; Flags: Fragment;+++[H3BMU1_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000454541}; Flags: Fragment;+++[H3BPP6_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455409}; Flags: Fragment;+++[H3BQ38_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455590}; Flags: Fragment;+++[H3BQF7_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455757}; Flags: Fragment;+++[H3BRE2_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000456200}; Flags: Fragment;+++[H3BUI0_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000457646}; Flags: Fragment;+++[J3KR23_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000414942}; Flags: Fragment;+++[J3QQP8_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000463833};"]
[98,"'ACYP2'",206,194,201,200.333333333333,"00627///Aminobenzoate degradation+++01120///Microbial metabolism in diverse environments+++00620///Pyruvate metabolism",null,null,"R00317///Acetyl phosphate phosphohydrolase   Acetyl phosphate + H2O <=> Acetate + Orthophosphate+++R01515///3-Phospho-D-glyceroyl phosphate phosphohydrolase   3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate+++R01421///Benzoyl phosphate phosphohydrolase   Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate","GO:0005623///cell+++GO:1990111///spermatoproteasome complex+++GO:0017053///transcriptional repressor complex+++GO:0035868///alphav-beta3 integrin-HMGB1 complex+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005839///proteasome core complex+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000793///condensed chromosome+++GO:0070062///extracellular exosome","GO:0042802///identical protein binding+++GO:0003998///acylphosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0006796///phosphate-containing compound metabolic process","acylphosphatase 2","[ACYP2_HUMAN|Reviewed]RecName: Full=Acylphosphatase-2; EC=3.6.1.7; AltName: Full=Acylphosphatase, muscle type isozyme; AltName: Full=Acylphosphate phosphohydrolase 2;+++[A0A140VJD7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[D6W5B6_HUMAN|Unreviewed]SubName: Full=Acylphosphatase 2, muscle type, isoform CRA_a {ECO:0000313|EMBL:EAX00155.1};+++[E9PF46_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[F8WA34_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[Q4ZFV7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ACYP2 {ECO:0000313|EMBL:AAX88874.1}; Flags: Fragment;+++[Q53TK7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX1_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX8_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475333};+++[U3KQ09_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475424};+++[U3KQ94_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475658}; SubName: Full=HCG2040114, isoform CRA_a {ECO:0000313|EMBL:EAX00159.1};+++[U3KQL2_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520};"]
[9801,"'MRPL19'",357,247,262,288.666666666667,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0015934///large ribosomal subunit+++GO:0005840///ribosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0031965///nuclear membrane","GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006412///translation+++GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:1990830///cellular response to leukemia inhibitory factor","mitochondrial ribosomal protein L19","[RM19_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L19, mitochondrial; Short=L19mt; Short=MRP-L19; AltName: Full=39S ribosomal protein L15, mitochondrial; Short=L15mt; Short=MRP-L15; AltName: Full=Mitochondrial large ribosomal subunit protein bL19m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[A0A0A0MRF4_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000351639};+++[H7C2J0_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000406267}; Flags: Fragment;+++[S4R3W9_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000474821}; Flags: Fragment;+++[S4R455_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000475090}; Flags: Fragment;"]
[9802,"'DAZAP2'",2888,2779,2884,2850.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0030971///receptor tyrosine kinase binding+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding","GO:0071902///positive regulation of protein serine/threonine kinase activity","DAZ associated protein 2","[DAZP2_HUMAN|Reviewed]RecName: Full=DAZ-associated protein 2; AltName: Full=Deleted in azoospermia-associated protein 2;+++[A0A024R110_HUMAN|Unreviewed]SubName: Full=DAZ associated protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW58182.1};+++[E9PE89_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000404968};+++[F8VUW5_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000447842};+++[S4R3Q0_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000474597};"]
[9804,"'TOMM20'",2283,1840,2084,2069,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005740///mitochondrial envelope+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0005741///mitochondrial outer membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0030943///mitochondrion targeting sequence binding+++GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051082///unfolded protein binding","GO:0016031///tRNA import into mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006626///protein targeting to mitochondrion+++GO:0006886///intracellular protein transport+++GO:0014850///response to muscle activity+++GO:0016579///protein deubiquitination+++GO:1905242///response to 3,3',5-triiodo-L-thyronine+++GO:0006605///protein targeting+++GO:0015031///protein transport+++GO:0070096///mitochondrial outer membrane translocase complex assembly","translocase of outer mitochondrial membrane 20","[TOM20_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM20 homolog; AltName: Full=Mitochondrial 20 kDa outer membrane protein; AltName: Full=Outer mitochondrial membrane receptor Tom20;+++[A0A024R3W2_HUMAN|Unreviewed]SubName: Full=Translocase of outer mitochondrial membrane 20 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW70004.1};"]
[9805,"'SCRN1'",2786,2568,2470,2608,{"$nulls":4},"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016805///dipeptidase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0006887///exocytosis+++GO:0006508///proteolysis","secernin 1","[SCRN1_HUMAN|Reviewed]RecName: Full=Secernin-1;+++[A0A024RA21_HUMAN|Unreviewed]SubName: Full=Secernin 1, isoform CRA_a {ECO:0000313|EMBL:EAW93927.1};+++[A0A090N7T9_HUMAN|Unreviewed]SubName: Full=Secernin 1 {ECO:0000313|EMBL:EAL24458.1};+++[B8ZZP4_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000387052};+++[C9J7U9_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000406289}; Flags: Fragment;+++[C9K052_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000413184}; Flags: Fragment;"]
[9806,"'SPOCK2'",58,41,73,57.3333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix","GO:0005509///calcium ion binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0050840///extracellular matrix binding+++GO:0005539///glycosaminoglycan binding+++GO:0005518///collagen binding","GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0010951///negative regulation of endopeptidase activity+++GO:2000147///positive regulation of cell motility+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0007416///synapse assembly+++GO:0045595///regulation of cell differentiation+++GO:0030198///extracellular matrix organization","SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2","[TICN2_HUMAN|Reviewed]RecName: Full=Testican-2; AltName: Full=SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2; Flags: Precursor;+++[A0A024QZQ5_HUMAN|Unreviewed]SubName: Full=Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (Testican) 2, isoform CRA_b {ECO:0000313|EMBL:EAW54443.1};+++[F5H283_HUMAN|Unreviewed]SubName: Full=Testican-2 {ECO:0000313|Ensembl:ENSP00000439445};+++[L8E8K3_HUMAN|Unreviewed]SubName: Full=Alternative protein SPOCK2 {ECO:0000313|EMBL:CCQ43459.1};"]
[9807,"'IP6K1'",1158,1205,1076,1146.33333333333,"04138///Autophagy - yeast+++04070///Phosphatidylinositol signaling system",null,null,"R10548///ATP:1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 5-phosphotransferase   ATP + 1-Diphosinositol pentakisphosphate <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate+++R09087///ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase   ATP + Phytic acid <=> ADP + 5-PP-InsP5","GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0052839///inositol diphosphate tetrakisphosphate kinase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0000829///inositol heptakisphosphate kinase activity+++GO:0016301///kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity+++GO:0005524///ATP binding+++GO:0052836///inositol 5-diphosphate pentakisphosphate 5-kinase activity","GO:0043647///inositol phosphate metabolic process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0016310///phosphorylation","inositol hexakisphosphate kinase 1","[IP6K1_HUMAN|Reviewed]RecName: Full=Inositol hexakisphosphate kinase 1; Short=InsP6 kinase 1; EC=2.7.4.21; AltName: Full=Inositol hexaphosphate kinase 1;+++[A0A024R2X2_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[C9JNA8_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[L8EAR7_HUMAN|Unreviewed]SubName: Full=Alternative protein IP6K1 {ECO:0000313|EMBL:CCQ43876.1};"]
[9810,"'RNF40'",2632,2905,2713,2750,{"$nulls":4},"GO:0033503///HULC complex+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0005634///nucleus+++GO:0000151///ubiquitin ligase complex+++GO:0043679///axon terminus+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0017075///syntaxin-1 binding+++GO:0042803///protein homodimerization activity","GO:0043434///response to peptide hormone+++GO:0016567///protein ubiquitination+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0007346///regulation of mitotic cell cycle+++GO:0006325///chromatin organization+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0033523///histone H2B ubiquitination+++GO:0010390///histone monoubiquitination","ring finger protein 40","[BRE1B_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase BRE1B; Short=BRE1-B; EC=2.3.2.27 {ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:19410543}; AltName: Full=95 kDa retinoblastoma-associated protein; Short=RBP95; AltName: Full=RING finger protein 40; AltName: Full=RING-type E3 ubiquitin transferase BRE1B {ECO:0000305};+++[A0A087WTK2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A0A0S2Z4Z2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[A0A0S2Z537_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A8K6K1_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BP71_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BQ99_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BS50_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BUL6_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[I3L332_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[R4GN66_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase BRE1B {ECO:0000313|Ensembl:ENSP00000473507}; Flags: Fragment;"]
[9811,"'CTIF'",1369,1350,1412,1377,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0008494///translation activator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045727///positive regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006417///regulation of translation","cap binding complex dependent translation initiation factor","[CTIF_HUMAN|Reviewed]RecName: Full=CBP80/20-dependent translation initiation factor;+++[A0A024R259_HUMAN|Unreviewed]SubName: Full=KIAA0427, isoform CRA_a {ECO:0000313|EMBL:EAW62927.1};+++[K7EK08_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000465405}; Flags: Fragment;+++[K7EPK6_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467425}; Flags: Fragment;+++[K7EQS5_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467957}; Flags: Fragment;+++[K7EQS9_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467965}; Flags: Fragment;"]
[9812,"'DELE1'",1152,1313,1243,1236,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00606///Early infantile epileptic encephalopathy+++H01775///PCDH19-related epilepsy syndrome",null,null,"GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process","DAP3 binding cell death enhancer 1","[DELE1_HUMAN|Reviewed]RecName: Full=DAP3-binding cell death enhancer 1 {ECO:0000312|HGNC:HGNC:28969}; AltName: Full=Death ligand signal enhancer {ECO:0000303|PubMed:20563667}; Flags: Precursor;+++[D6RBI8_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000422686}; Flags: Fragment;+++[H0YA48_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000426138}; Flags: Fragment;"]
[9813,"'EFCAB14'",1698,1691,1703,1697.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding",null,"EF-hand calcium binding domain 14","[EFC14_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 14;+++[S4R3Q1_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000474599}; Flags: Fragment;"]
[9814,"'SFI1'",166.04,192,160.01,172.683333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005814///centriole","GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0005515///protein binding+++GO:0004609///phosphatidylserine decarboxylase activity+++GO:0019902///phosphatase binding","GO:0006629///lipid metabolic process+++GO:0010923///negative regulation of phosphatase activity+++GO:0016540///protein autoprocessing+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0008654///phospholipid biosynthetic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0000086///G2/M transition of mitotic cell cycle","SFI1 centrin binding protein","[SFI1_HUMAN|Reviewed]RecName: Full=Protein SFI1 homolog; Short=hSFI1;+++[A0A024R1K2_HUMAN|Unreviewed]SubName: Full=Sfi1 homolog, spindle assembly associated (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW59983.1};+++[D3YTJ2_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000401199};+++[E5RJU6_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000430488};+++[H0Y5I7_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000398871}; Flags: Fragment;+++[H0Y836_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000416931}; Flags: Fragment;+++[H7BZF3_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000389364}; Flags: Fragment;+++[H7C2F1_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000405541}; Flags: Fragment;+++[X6RJF9_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000411793}; Flags: Fragment;"]
[9815,"'GIT2'",989,960,978,975.666666666667,"04144///Endocytosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation","GIT ArfGAP 2","[GIT2_HUMAN|Reviewed]RecName: Full=ARF GTPase-activating protein GIT2; Short=ARF GAP GIT2; AltName: Full=Cool-interacting tyrosine-phosphorylated protein 2; Short=CAT-2; Short=CAT2; AltName: Full=G protein-coupled receptor kinase-interactor 2; AltName: Full=GRK-interacting protein 2;+++[A0A024RBI8_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase interactor 2, isoform CRA_a {ECO:0000313|EMBL:EAW97886.1};+++[B5BU58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70108.1};+++[F8VXI9_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000448832};+++[F8W822_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000323833};+++[F8WAK2_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000346585};+++[Q68DM7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G01261 {ECO:0000313|EMBL:CAH18193.1}; Flags: Fragment;+++[Q6FI58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70242.1}; SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 variant {ECO:0000313|EMBL:BAD96456.1}; SubName: Full=GIT2 protein {ECO:0000313|EMBL:CAG38599.1};+++[R4GNG3_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000473637}; Flags: Fragment;"]
[9816,"'URB2'",151,172,143,155.333333333333,{"$nulls":4},"GO:0030496///midbody+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016235///aggresome",null,"GO:0042254///ribosome biogenesis","URB2 ribosome biogenesis homolog","[URB2_HUMAN|Reviewed]RecName: Full=Unhealthy ribosome biogenesis protein 2 homolog;+++[Q5VYD0_HUMAN|Unreviewed]SubName: Full=Unhealthy ribosome biogenesis protein 2 homolog {ECO:0000313|Ensembl:ENSP00000395107}; Flags: Fragment;+++[Q6PCC8_HUMAN|Unreviewed]SubName: Full=URB2 protein {ECO:0000313|EMBL:AAH59381.1}; Flags: Fragment;"]
[9817,"'KEAP1'",1173,1335,1206,1238,"05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04120///Ubiquitin mediated proteolysis+++05225///Hepatocellular carcinoma","H00048///Hepatocellular carcinoma",null,null,"GO:0005884///actin filament+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0030496///midbody+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0042802///identical protein binding+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043687///post-translational protein modification+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0071353///cellular response to interleukin-4+++GO:0016032///viral process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0016567///protein ubiquitination+++GO:0045604///regulation of epidermal cell differentiation","kelch like ECH associated protein 1","[KEAP1_HUMAN|Reviewed]RecName: Full=Kelch-like ECH-associated protein 1; AltName: Full=Cytosolic inhibitor of Nrf2; Short=INrf2; AltName: Full=Kelch-like protein 19;+++[A0A024R7C0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW84112.1};+++[K7EJ49_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465024}; Flags: Fragment;+++[K7EJD8_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465126}; Flags: Fragment;+++[K7EMY1_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000466704}; Flags: Fragment;+++[K7EPZ3_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000467601}; Flags: Fragment;+++[K7EQX2_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468014}; Flags: Fragment;+++[K7ESE0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468671}; Flags: Fragment;"]
[9818,"'NUP58'",488,456,465,469.666666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005643///nuclear pore+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0015031///protein transport+++GO:0006913///nucleocytoplasmic transport+++GO:0006406///mRNA export from nucleus+++GO:0016032///viral process+++GO:0051260///protein homooligomerization+++GO:0051028///mRNA transport+++GO:0042306///regulation of protein import into nucleus+++GO:0051290///protein heterotetramerization+++GO:0051291///protein heterooligomerization+++GO:0070208///protein heterotrimerization","nucleoporin 58","[NUP58_HUMAN|Reviewed]RecName: Full=Nucleoporin p58/p45 {ECO:0000305}; AltName: Full=58 kDa nucleoporin {ECO:0000312|HGNC:HGNC:20261}; AltName: Full=Nucleoporin-like protein 1;+++[F8WBZ1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418244};+++[F8WC35_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418904};+++[F8WCJ8_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418341};+++[H7BYF2_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000371166}; Flags: Fragment;+++[Q5JRG1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000408147}; Flags: Fragment;"]
[9819,"'TSC22D2'",569,647,644,620,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006970///response to osmotic stress","TSC22 domain family member 2","[T22D2_HUMAN|Reviewed]RecName: Full=TSC22 domain family protein 2; AltName: Full=TSC22-related-inducible leucine zipper protein 4;+++[B4DN36_HUMAN|Unreviewed]SubName: Full=TSC22 domain family, member 2, isoform CRA_d {ECO:0000313|EMBL:EAW78841.1}; SubName: Full=cDNA FLJ51900, highly similar to TSC22 domain family protein 2 {ECO:0000313|EMBL:BAG60098.1};+++[H0Y865_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000417747}; Flags: Fragment;+++[H0Y8E9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000420689}; Flags: Fragment;+++[H7C4U3_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000418149}; Flags: Fragment;"]
[9820,"'CUL7'",1413,1654,1540,1535.66666666667,"04120///Ubiquitin mediated proteolysis","H00509///3M syndrome",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005680///anaphase-promoting complex+++GO:1990393///3M complex+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0007030///Golgi organization+++GO:0006508///proteolysis+++GO:0001890///placenta development+++GO:0000226///microtubule cytoskeleton organization+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001570///vasculogenesis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0007088///regulation of mitotic nuclear division+++GO:0001837///epithelial to mesenchymal transition+++GO:0000281///mitotic cytokinesis+++GO:0016567///protein ubiquitination+++GO:0016032///viral process","cullin 7","[CUL7_HUMAN|Reviewed]RecName: Full=Cullin-7; Short=CUL-7;+++[L8E835_HUMAN|Unreviewed]SubName: Full=Alternative protein CUL7 {ECO:0000313|EMBL:CCQ43460.1};"]
[9821,"'RB1CC1'",795,766,750,770.333333333333,"04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0034045///phagophore assembly site membrane+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000407///phagophore assembly site+++GO:0005789///endoplasmic reticulum membrane+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0019898///extrinsic component of membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0007507///heart development+++GO:0043066///negative regulation of apoptotic process+++GO:0000045///autophagosome assembly+++GO:0030242///autophagy of peroxisome+++GO:0001934///positive regulation of protein phosphorylation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0001889///liver development+++GO:0000422///autophagy of mitochondrion+++GO:0016241///regulation of macroautophagy+++GO:0061709///reticulophagy+++GO:0006914///autophagy+++GO:0007049///cell cycle+++GO:0061723///glycophagy+++GO:0016236///macroautophagy+++GO:0045793///positive regulation of cell size+++GO:0046330///positive regulation of JNK cascade","RB1 inducible coiled-coil 1","[RBCC1_HUMAN|Reviewed]RecName: Full=RB1-inducible coiled-coil protein 1; AltName: Full=FAK family kinase-interacting protein of 200 kDa; Short=FIP200;+++[E5RH44_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429918}; Flags: Fragment;+++[E5RH63_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429879}; Flags: Fragment;+++[E5RHX0_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429611}; Flags: Fragment;+++[E5RJC1_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429115};+++[H0YC28_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430792}; Flags: Fragment;+++[H0YC30_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430809}; Flags: Fragment;"]
[9823,"'ARMCX2'",751,704,757,737.333333333333,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane",null,"GO:0034613///cellular protein localization+++GO:0045944///positive regulation of transcription by RNA polymerase II","armadillo repeat containing X-linked 2","[ARMX2_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 2; AltName: Full=ARM protein lost in epithelial cancers on chromosome X 2; Short=Protein ALEX2;+++[A0A024RCG7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2, isoform CRA_a {ECO:0000313|EMBL:EAX02889.1};+++[A0A0B4J1X4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000393778}; Flags: Fragment;+++[A0A1B0GXK8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000415490}; Flags: Fragment;+++[A8K5M7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76303, highly similar to Homo sapiens armadillo repeat containing, X-linked 2 (ARMCX2), mRNA {ECO:0000313|EMBL:BAF84031.1};+++[Q5H9D7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42024.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000405376}; Flags: Fragment;+++[Q5H9D8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42023.1}; Flags: Fragment;+++[Q5H9E0_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42021.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000410151}; Flags: Fragment;+++[Q5H9E1_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42020.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000412481}; Flags: Fragment;"]
[9824,"'ARHGAP11A'",80,89.96,75.8,81.92,{"$nulls":4},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction","Rho GTPase activating protein 11A","[RHGBA_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 11A; AltName: Full=Rho-type GTPase-activating protein 11A;+++[A0A2X0SFK9_HUMAN|Unreviewed]SubName: Full=ARHGAP11A {ECO:0000313|EMBL:SPT35684.1}; Flags: Fragment;+++[H3BQ41_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000455593}; Flags: Fragment;+++[H3BR51_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000456078};"]
[9825,"'SPATA2'",430,396,416,414,"04217///Necroptosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007283///spermatogenesis+++GO:0012501///programmed cell death+++GO:0007275///multicellular organism development+++GO:0050727///regulation of inflammatory response+++GO:0060544///regulation of necroptotic process+++GO:1990108///protein linear deubiquitination+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0070536///protein K63-linked deubiquitination","spermatogenesis associated 2","[SPAT2_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 2 {ECO:0000303|PubMed:27307491, ECO:0000303|PubMed:27458237};+++[A8K0S9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78311, highly similar to Homo sapiens spermatogenesis associated 2 (SPATA2), mRNA {ECO:0000313|EMBL:BAF82333.1};+++[B4DID4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50158, highly similar to Spermatogenesis-associated protein 2 {ECO:0000313|EMBL:BAG58446.1};+++[L8E7J6_HUMAN|Unreviewed]SubName: Full=Alternative protein SPATA2 {ECO:0000313|EMBL:CCQ43104.1};"]
[9826,"'ARHGEF11'",1089,1341,1269,1233,"05200///Pathways in cancer+++04928///Parathyroid hormone synthesis, secretion and action+++04270///Vascular smooth muscle contraction+++05163///Human cytomegalovirus infection",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0030010///establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0006941///striated muscle contraction+++GO:0001558///regulation of cell growth+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","Rho guanine nucleotide exchange factor 11","[ARHGB_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 11; AltName: Full=PDZ-RhoGEF;+++[A0A2X0SFB0_HUMAN|Unreviewed]SubName: Full=ARHGEF11 {ECO:0000313|EMBL:SPT35722.1}; Flags: Fragment;"]
[9827,"'RGP1'",253,301,277,277,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0034066///RIC1-RGP1 guanyl-nucleotide exchange factor complex+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0032588///trans-Golgi network membrane+++GO:0000139///Golgi membrane+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0017137///Rab GTPase binding","GO:1903363///negative regulation of cellular protein catabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0042147///retrograde transport, endosome to Golgi","RGP1 homolog, RAB6A GEF complex partner 1","[RGP1_HUMAN|Reviewed]RecName: Full=RAB6A-GEF complex partner protein 2 {ECO:0000305}; AltName: Full=Retrograde Golgi transport protein RGP1 homolog {ECO:0000250|UniProtKB:P16664};+++[A8K0K1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76996 {ECO:0000313|EMBL:BAF82255.1};"]
[9828,"'ARHGEF17'",2714,2988,2591,2764.33333333333,{"$nulls":4},"GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","Rho guanine nucleotide exchange factor 17","[ARHGH_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 17; AltName: Full=164 kDa Rho-specific guanine-nucleotide exchange factor; Short=p164-RhoGEF; Short=p164RhoGEF; AltName: Full=Tumor endothelial marker 4;+++[A0A2R8Y4D7_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000493940};+++[A0A2X0TVV1_HUMAN|Unreviewed]SubName: Full=ARHGEF17 {ECO:0000313|EMBL:SPT35726.1}; Flags: Fragment;+++[H0YFZ8_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000441135}; Flags: Fragment;"]
[9829,"'DNAJC6'",320,298,254,290.666666666667,"04144///Endocytosis",{"$nulls":3},"GO:0045202///synapse+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0030276///clathrin binding+++GO:0017124///SH3 domain binding+++GO:0004725///protein tyrosine phosphatase activity","GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0061024///membrane organization+++GO:0006470///protein dephosphorylation+++GO:0072583///clathrin-dependent endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:0072318///clathrin coat disassembly+++GO:0035335///peptidyl-tyrosine dephosphorylation","DnaJ heat shock protein family (Hsp40) member C6","[AUXI_HUMAN|Reviewed]RecName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000305}; EC=3.1.3.48; AltName: Full=DnaJ homolog subfamily C member 6 {ECO:0000312|HGNC:HGNC:15469};+++[L0N9S0_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily C, member 6 {ECO:0000313|EMBL:CCE46052.1}; Flags: Fragment;+++[S4R305_HUMAN|Unreviewed]SubName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000313|Ensembl:ENSP00000473821}; Flags: Fragment;"]
[983,"'CDK1'",10,8,6,8,"05168///Herpes simplex infection+++05203///Viral carcinogenesis+++04114///Oocyte meiosis+++04540///Gap junction+++04110///Cell cycle+++05169///Epstein-Barr virus infection+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++04115///p53 signaling pathway",null,"M00693///Cell cycle - G2/M transition",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005813///centrosome+++GO:0070062///extracellular exosome+++GO:0005876///spindle microtubule+++GO:0030496///midbody+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005654///nucleoplasm+++GO:0097125///cyclin B1-CDK1 complex+++GO:0072686///mitotic spindle+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0035173///histone kinase activity+++GO:0005524///ATP binding+++GO:0030544///Hsp70 protein binding+++GO:0016740///transferase activity+++GO:0003682///chromatin binding+++GO:0001618///virus receptor activity+++GO:0000166///nucleotide binding+++GO:0097472///cyclin-dependent protein kinase activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0000187///activation of MAPK activity+++GO:0007344///pronuclear fusion+++GO:0014070///response to organic cyclic compound+++GO:0006468///protein phosphorylation+++GO:0030855///epithelial cell differentiation+++GO:0030261///chromosome condensation+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0014038///regulation of Schwann cell differentiation+++GO:0016572///histone phosphorylation+++GO:0046688///response to copper ion+++GO:0018105///peptidyl-serine phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0010628///positive regulation of gene expression+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0016477///cell migration+++GO:0006915///apoptotic process+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0065003///protein-containing complex assembly+++GO:0008283///cell proliferation+++GO:0045995///regulation of embryonic development+++GO:0044772///mitotic cell cycle phase transition+++GO:0016579///protein deubiquitination+++GO:0045471///response to ethanol+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0048678///response to axon injury+++GO:0031100///animal organ regeneration+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0014075///response to amine+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0045740///positive regulation of DNA replication+++GO:0007077///mitotic nuclear envelope disassembly+++GO:0007569///cell aging+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0006260///DNA replication+++GO:0007098///centrosome cycle+++GO:0051301///cell division+++GO:0090166///Golgi disassembly+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0010243///response to organonitrogen compound+++GO:0070301///cellular response to hydrogen peroxide+++GO:0034501///protein localization to kinetochore+++GO:0042493///response to drug+++GO:0006281///DNA repair+++GO:0043066///negative regulation of apoptotic process+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0046718///viral entry into host cell+++GO:0000278///mitotic cell cycle+++GO:1905448///positive regulation of mitochondrial ATP synthesis coupled electron transport+++GO:0033160///positive regulation of protein import into nucleus, translocation+++GO:0046686///response to cadmium ion+++GO:0055015///ventricular cardiac muscle cell development+++GO:0009636///response to toxic substance+++GO:0016310///phosphorylation+++GO:0014823///response to activity","cyclin dependent kinase 1","[CDK1_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 1; Short=CDK1; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cell division control protein 2 homolog; AltName: Full=Cell division protein kinase 1; AltName: Full=p34 protein kinase;+++[A0A024QZJ8_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2, G1 to S and G2 to M, isoform CRA_c {ECO:0000313|EMBL:EAW54207.1};+++[A0A024QZP7_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2, G1 to S and G2 to M, isoform CRA_a {ECO:0000313|EMBL:EAW54209.1}; SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000397973};+++[A0A087WZZ9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000482996};+++[B7Z3D6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50170, highly similar to Cell division control protein 2 homolog {ECO:0000313|EMBL:BAH12172.1};+++[E5RIU6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000430665}; Flags: Fragment;+++[I6L9I5_HUMAN|Unreviewed]SubName: Full=CDC2 protein {ECO:0000313|EMBL:AAI07751.1};"]
[9830,"'TRIM14'",141,233,190.03,188.01,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0002376///immune system process+++GO:0032897///negative regulation of viral transcription+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0045087///innate immune response","tripartite motif containing 14","[TRI14_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 14;+++[A0A024R143_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_c {ECO:0000313|EMBL:EAW58876.1};+++[A0A024R165_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_a {ECO:0000313|EMBL:EAW58878.1};+++[F2Z2M2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 14 {ECO:0000313|Ensembl:ENSP00000428805};"]
[9831,"'ZNF623'",194,208,194,198.666666666667,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,"R01724///5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming) Nicotinate D-ribonucleotide + Diphosphate + ADP + Orthophosphate <=> Nicotinate + 5-Phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + H+","GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 623","[ZN623_HUMAN|Reviewed]RecName: Full=Zinc finger protein 623;+++[A0A0A0MT18_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000411139};+++[A0A0J9YW98_HUMAN|Unreviewed]SubName: Full=HCG31704 {ECO:0000313|EMBL:EAW82216.1}; SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000487869};"]
[9832,"'JAKMIP2'",22,36,33,30.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019900///kinase binding",null,"janus kinase and microtubule interacting protein 2","[JKIP2_HUMAN|Reviewed]RecName: Full=Janus kinase and microtubule-interacting protein 2; AltName: Full=CTCL tumor antigen HD-CL-04; AltName: Full=Neuroendocrine long coiled-coil protein 1;+++[Q05DV4_HUMAN|Unreviewed]SubName: Full=JAKMIP2 protein {ECO:0000313|EMBL:AAH03189.1}; Flags: Fragment;"]
[9833,"'MELK'",13,6,12,10.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005938///cell cortex+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005509///calcium ion binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0008289///lipid binding+++GO:0005524///ATP binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0030097///hemopoiesis+++GO:0016310///phosphorylation+++GO:0006915///apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0008283///cell proliferation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0007049///cell cycle+++GO:0061351///neural precursor cell proliferation","maternal embryonic leucine zipper kinase","[MELK_HUMAN|Reviewed]RecName: Full=Maternal embryonic leucine zipper kinase; Short=hMELK; EC=2.7.11.1; AltName: Full=Protein kinase Eg3; Short=pEg3 kinase; AltName: Full=Protein kinase PK38; Short=hPK38; AltName: Full=Tyrosine-protein kinase MELK; EC=2.7.10.2;+++[A0A0D9SFB9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486459};+++[A0A0D9SFF9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486558};+++[A0A0D9SFL8_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486717};+++[A0A0D9SGI4_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000487536}; Flags: Fragment;+++[B7Z1G6_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00804148}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00804148};"]
[9836,"'LCMT2'",204,200,181,195,{"$nulls":3},"R10586///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-carboxypropyl]wyosine37-O}-methyltransferase   7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine <=> 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-homocysteine+++R10587///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methyltransferase (carbon dioxide-adding)   7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine + CO2 <=> Wybutosine in tRNA(Phe) + S-Adenosyl-L-homocysteine","GO:0005737///cytoplasm","GO:0008168///methyltransferase activity+++GO:0018423///protein C-terminal leucine carboxyl O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008175///tRNA methyltransferase activity","GO:0008033///tRNA processing+++GO:0006400///tRNA modification+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0031591///wybutosine biosynthetic process+++GO:0006481///C-terminal protein methylation","leucine carboxyl methyltransferase 2","[TYW4_HUMAN|Reviewed]RecName: Full=tRNA wybutosine-synthesizing protein 4; Short=tRNA yW-synthesizing protein 4; EC=2.1.1.290; EC=2.3.1.231; AltName: Full=Leucine carboxyl methyltransferase 2; AltName: Full=tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; AltName: Full=tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase;+++[H3BU01_HUMAN|Unreviewed]SubName: Full=tRNA wybutosine-synthesizing protein 4 {ECO:0000313|Ensembl:ENSP00000457403};"]
[9837,"'GINS1'",27,15,29,23.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00286///GINS complex",null,"GO:0005634///nucleus+++GO:0000811///GINS complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0043138///3'-5' DNA helicase activity","GO:0006271///DNA strand elongation involved in DNA replication+++GO:0001833///inner cell mass cell proliferation+++GO:1902983///DNA strand elongation involved in mitotic DNA replication+++GO:0032508///DNA duplex unwinding+++GO:0006260///DNA replication","GINS complex subunit 1","[PSF1_HUMAN|Reviewed]RecName: Full=DNA replication complex GINS protein PSF1; AltName: Full=GINS complex subunit 1;+++[L8ECJ2_HUMAN|Unreviewed]SubName: Full=Alternative protein GINS1 {ECO:0000313|EMBL:CCQ43662.1};"]
[9839,"'ZEB2'",522,702,556,593.333333333333,"05206///MicroRNAs in cancer","H00961///Posterior polymorphous corneal dystrophy (PPCD)+++H00908///Mowat-Wilson syndrome+++H00960///Fuchs corneal dystrophy (FECD)",null,null,"GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0019208///phosphatase regulator activity+++GO:0070412///R-SMAD binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0021957///corticospinal tract morphogenesis+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021766///hippocampus development+++GO:0097324///melanocyte migration+++GO:0001755///neural crest cell migration+++GO:0050772///positive regulation of axonogenesis+++GO:0021540///corpus callosum morphogenesis+++GO:0048066///developmental pigmentation+++GO:0043507///positive regulation of JUN kinase activity+++GO:1902748///positive regulation of lens fiber cell differentiation+++GO:0048668///collateral sprouting+++GO:0048598///embryonic morphogenesis+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0061373///mammillary axonal complex development+++GO:1903056///regulation of melanosome organization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021846///cell proliferation in forebrain+++GO:0007399///nervous system development+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development","zinc finger E-box binding homeobox 2","[ZEB2_HUMAN|Reviewed]RecName: Full=Zinc finger E-box-binding homeobox 2; AltName: Full=Smad-interacting protein 1; Short=SMADIP1; AltName: Full=Zinc finger homeobox protein 1b;+++[A0A0D9SF71_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486341};+++[A0A0D9SF74_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486346}; Flags: Fragment;+++[A0A0D9SG93_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487261};+++[A0A0D9SGG5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487476}; Flags: Fragment;+++[A0A1B0GTH3_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000489701}; Flags: Fragment;+++[A0A1B0GUM8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490175};+++[A0A1B0GV02_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490317};+++[A0A1B0GVV8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490673};+++[A0A1B0GW50_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490776};+++[A0A1B0GWA7_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490851};+++[A0A1B0GWI0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490934};+++[A0A1W2PS25_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000492572}; Flags: Fragment;+++[A0A1X7SC99_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490293}; Flags: Fragment;+++[A0A2R8YDQ8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000494820}; Flags: Fragment;+++[A0JP08_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|EMBL:AAI27102.1, ECO:0000313|Ensembl:ENSP00000302501};+++[C9JU62_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000400993}; Flags: Fragment;+++[C9JUQ1_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000399451}; Flags: Fragment;+++[E7ESP8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000376601}; Flags: Fragment;+++[E7EUW9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000395496}; Flags: Fragment;+++[E7EVG9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000387256}; Flags: Fragment;+++[H7C0G0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000394777};+++[Q53TD9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93276.1}; Flags: Fragment;+++[Q53TG0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93269.1}; Flags: Fragment;+++[Q60F94_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60928.1};+++[Q60F95_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60927.1};+++[Q9H4F4_HUMAN|Unreviewed]SubName: Full=Survival interacting protein 1 {ECO:0000313|EMBL:CAC16171.1}; Flags: Fragment;+++[U3KPV5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475267}; Flags: Fragment;+++[U3KPX6_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475329};+++[U3KQ33_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475502};+++[U3KQ51_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475553};"]
[984,"'CDK11B'",972.7,1058.6,885.18,972.16,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016310///phosphorylation+++GO:0050684///regulation of mRNA processing+++GO:0001558///regulation of cell growth+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process","cyclin dependent kinase 11B","[CD11B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 11B; EC=2.7.11.22; AltName: Full=Cell division cycle 2-like protein kinase 1; Short=CLK-1; AltName: Full=Cell division protein kinase 11B; AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA; AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L1; AltName: Full=p58 CLK-1;+++[A0A087WYI9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000481846};+++[A0A087X1I0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000484222};+++[A0A0D9SEI3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485705};+++[A0A0D9SEN2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485849};+++[A0A0D9SER5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485937};+++[A4VCI5_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAI39778.1}; Flags: Fragment;+++[B4DII1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59025, moderately similar to PITSLRE serine/threonine-protein kinaseCDC2L1 {ECO:0000313|EMBL:BAG58493.1};+++[Q6PK02_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAH09375.1}; Flags: Fragment;"]
[9840,"'TESPA1'",2,6.31,0.67,2.99333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0008180///COP9 signalosome","GO:0005102///signaling receptor binding","GO:0010387///COP9 signalosome assembly+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0050862///positive regulation of T cell receptor signaling pathway","thymocyte expressed, positive selection associated 1","[TESP1_HUMAN|Reviewed]RecName: Full=Protein TESPA1; AltName: Full=Thymocyte-expressed positive selection-associated protein 1;+++[A0A024RB00_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_a {ECO:0000313|EMBL:EAW96798.1};+++[A0A024RB73_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_c {ECO:0000313|EMBL:EAW96800.1};+++[E9PHY9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436635}; Flags: Fragment;+++[E9PIN8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000435734}; Flags: Fragment;+++[E9PIT9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433895}; Flags: Fragment;+++[E9PM24_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433187}; Flags: Fragment;+++[E9PN46_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434811};+++[E9PPW8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436286}; Flags: Fragment;+++[H0YDP3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434039}; Flags: Fragment;+++[H0YEX3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436753}; Flags: Fragment;"]
[9841,"'ZBTB24'",201,215,236,217.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 24","[ZBT24_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 24; AltName: Full=Zinc finger protein 450;"]
[9842,"'PLEKHM1'",1730,1656,1695,1693.66666666667,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0010008///endosome membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane","GO:0046872///metal ion binding","GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0035556///intracellular signal transduction+++GO:0032418///lysosome localization+++GO:0045780///positive regulation of bone resorption+++GO:1900029///positive regulation of ruffle assembly","pleckstrin homology and RUN domain containing M1","[PKHM1_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family M member 1; Short=PH domain-containing family M member 1; AltName: Full=162 kDa adapter protein; Short=AP162;+++[J3KRL8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462065}; Flags: Fragment;+++[J3KRU0_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462160};+++[J3KS30_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462282};+++[K7EII8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000464766};+++[K7EMP2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000466589}; Flags: Fragment;+++[K7EPF2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467356}; Flags: Fragment;+++[K7EQ68_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467695}; Flags: Fragment;"]
[9843,"'HEPH'",55,57,44,52,"00860///Porphyrin and chlorophyll metabolism+++04978///Mineral absorption",null,null,"R00078///Fe(II):oxygen oxidoreductase; Fe2+:oxygen   Oxygen + 4 Fe2+ + 4 H+ <=> 4 Fe3+ + 2 H2O","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005615///extracellular space","GO:0016491///oxidoreductase activity+++GO:0016722///oxidoreductase activity, oxidizing metal ions+++GO:0046872///metal ion binding+++GO:0008198///ferrous iron binding+++GO:0005507///copper ion binding+++GO:0004322///ferroxidase activity","GO:0006879///cellular iron ion homeostasis+++GO:0055114///oxidation-reduction process+++GO:0006825///copper ion transport+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0055072///iron ion homeostasis","hephaestin","[HEPH_HUMAN|Reviewed]RecName: Full=Hephaestin; EC=1.-.-.-; Flags: Precursor;+++[A0A0C4DG76_HUMAN|Unreviewed]SubName: Full=Hephaestin, isoform CRA_c {ECO:0000313|EMBL:EAX05387.1};+++[E7ES21_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000413211};+++[F8WBZ8_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000392319};+++[Q1HE23_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|EMBL:ABF47089.1};+++[Q5JZ07_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000396907}; Flags: Fragment;+++[Q5JZ08_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000398078}; Flags: Fragment;"]
[9844,"'ELMO1'",0,3,3,2,"05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++04062///Chemokine signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017124///SH3 domain binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0050690///regulation of defense response to virus by virus+++GO:0006909///phagocytosis+++GO:0030036///actin cytoskeleton organization+++GO:0016477///cell migration+++GO:0030029///actin filament-based process+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048870///cell motility+++GO:0006915///apoptotic process+++GO:0016601///Rac protein signal transduction+++GO:0006911///phagocytosis, engulfment","engulfment and cell motility 1","[ELMO1_HUMAN|Reviewed]RecName: Full=Engulfment and cell motility protein 1; AltName: Full=Protein ced-12 homolog;+++[A4D1X5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility 1 (Ced-12 homolog, C. elegans) {ECO:0000313|EMBL:EAL23978.1}; SubName: Full=Engulfment and cell motility 1, isoform CRA_c {ECO:0000313|EMBL:EAW94077.1}; SubName: Full=cDNA FLJ77700, highly similar to Homo sapiens engulfment and cell motility 1 (ELMO1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84473.1};+++[C9IZR8_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000406610}; Flags: Fragment;+++[C9J5X3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000397857}; Flags: Fragment;+++[C9JB20_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000391734}; Flags: Fragment;+++[C9JIW2_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000416090}; Flags: Fragment;+++[H7C0N5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000395933}; Flags: Fragment;+++[H7C0S6_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000396465}; Flags: Fragment;+++[H7C3P3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000413108}; Flags: Fragment;"]
[9846,"'GAB2'",1276,1259,1171,1235.33333333333,"05220///Chronic myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++04664///Fc epsilon RI signaling pathway+++04072///Phospholipase D signaling pathway+++04071///Sphingolipid signaling pathway+++04380///Osteoclast differentiation+++04014///Ras signaling pathway","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0005515///protein binding+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity","GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043306///positive regulation of mast cell degranulation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0007411///axon guidance","GRB2 associated binding protein 2","[GAB2_HUMAN|Reviewed]RecName: Full=GRB2-associated-binding protein 2; AltName: Full=GRB2-associated binder 2; AltName: Full=Growth factor receptor bound protein 2-associated protein 2; AltName: Full=pp100;+++[E9PJ26_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000431868}; Flags: Fragment;+++[E9PJE2_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000433762}; Flags: Fragment;"]
[9847,"'C2CD5'",299,250,218,255.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0001726///ruffle+++GO:0032587///ruffle membrane+++GO:0005815///microtubule organizing center","GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005544///calcium-dependent phospholipid binding","GO:0006906///vesicle fusion+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0046326///positive regulation of glucose import+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0065002///intracellular protein transmembrane transport+++GO:0031340///positive regulation of vesicle fusion+++GO:0032869///cellular response to insulin stimulus","C2 calcium dependent domain containing 5","[C2CD5_HUMAN|Reviewed]RecName: Full=C2 domain-containing protein 5; AltName: Full=C2 domain-containing phosphoprotein of 138 kDa;+++[A0A024RB03_HUMAN|Unreviewed]SubName: Full=KIAA0528, isoform CRA_b {ECO:0000313|EMBL:EAW96475.1};+++[B7ZLK1_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43860.1};+++[B7ZLK2_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43861.1};+++[H0YFC4_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000437935}; Flags: Fragment;+++[H0YFE9_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000438256}; Flags: Fragment;+++[H0YGU7_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000444857}; Flags: Fragment;"]
[9848,"'MFAP3L'",2081,1952,1830,1954.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"microfibril associated protein 3 like","[MFA3L_HUMAN|Reviewed]RecName: Full=Microfibrillar-associated protein 3-like; AltName: Full=Testis development protein NYD-SP9 {ECO:0000303|Ref.1}; Flags: Precursor;+++[D6R9L7_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423549}; Flags: Fragment;+++[D6RAB5_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000422791}; Flags: Fragment;+++[D6RCC0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423802}; Flags: Fragment;+++[D6RCF0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423722}; Flags: Fragment;+++[D6RDM6_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000425303}; Flags: Fragment;+++[D6RGZ8_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000426247}; Flags: Fragment;"]
[9849,"'ZNF518A'",159,171,175,168.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04064///NF-kappa B signaling pathway+++05340///Primary immunodeficiency+++04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway","H00085///Agammaglobulinemias",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 518A","[Z518A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 518A;+++[A0A087WWK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 518A {ECO:0000313|Ensembl:ENSP00000480280}; Flags: Fragment;"]
[9851,"'KIAA0753'",265,260,234,253,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0034451///centriolar satellite+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:0007099///centriole replication+++GO:0071539///protein localization to centrosome","KIAA0753","[MOONR_HUMAN|Reviewed]RecName: Full=Protein moonraker {ECO:0000303|PubMed:26297806}; Short=MNR {ECO:0000303|PubMed:26297806}; AltName: Full=OFD1- and FOPNL-interacting protein {ECO:0000303|PubMed:26643951};+++[F6SFD5_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000444946}; Flags: Fragment;+++[I3L0P7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458247}; Flags: Fragment;+++[I3L1P2_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458983}; Flags: Fragment;+++[I3L2A7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000459530}; Flags: Fragment;+++[I3L341_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460156}; Flags: Fragment;+++[I3L3Y0_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460816};"]
[9852,"'EPM2AIP1'",607,611,545,587.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0032868///response to insulin+++GO:2000467///positive regulation of glycogen (starch) synthase activity+++GO:0045725///positive regulation of glycogen biosynthetic process","EPM2A interacting protein 1","[EPMIP_HUMAN|Reviewed]RecName: Full=EPM2A-interacting protein 1; AltName: Full=Laforin-interacting protein;+++[A0A096LNL1_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485091}; Flags: Fragment;+++[A0A096LPB0_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485489}; Flags: Fragment;"]
[9853,"'RUSC2'",2666,2628,2492,2595.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0017137///Rab GTPase binding","GO:0008150///biological_process","RUN and SH3 domain containing 2","[RUSC2_HUMAN|Reviewed]RecName: Full=Iporin; AltName: Full=Interacting protein of Rab1; AltName: Full=RUN and SH3 domain-containing protein 2;"]
[9854,"'C2CD2L'",469,510,516,498.333333333333,"00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome+++H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0098592///cytoplasmic side of apical plasma membrane+++GO:0016020///membrane+++GO:0032541///cortical endoplasmic reticulum","GO:0008526///phosphatidylinositol transporter activity+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0043559///insulin binding+++GO:0005548///phospholipid transporter activity","GO:0015914///phospholipid transport+++GO:0006869///lipid transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus","C2CD2 like","[C2C2L_HUMAN|Reviewed]RecName: Full=Phospholipid transfer protein C2CD2L {ECO:0000305}; AltName: Full=C2 domain-containing protein 2-like {ECO:0000312|HGNC:HGNC:29000}; Short=C2CD2-like; AltName: Full=Transmembrane protein 24 {ECO:0000303|PubMed:28209843};+++[E9PK05_HUMAN|Unreviewed]SubName: Full=Phospholipid transfer protein C2CD2L {ECO:0000313|Ensembl:ENSP00000433600};+++[Q6DHX1_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH75832.1}; Flags: Fragment;+++[Q9BTM2_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH03598.2};"]
[9855,"'FARP2'",224,283,245,250.666666666667,"04015///Rap1 signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030316///osteoclast differentiation+++GO:0033623///regulation of integrin activation+++GO:0031532///actin cytoskeleton reorganization+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0022405///hair cycle process+++GO:0016601///Rac protein signal transduction+++GO:0071800///podosome assembly+++GO:0007155///cell adhesion+++GO:0035023///regulation of Rho protein signal transduction+++GO:0016322///neuron remodeling","FERM, ARH/RhoGEF and pleckstrin domain protein 2","[FARP2_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2; AltName: Full=FERM domain-including RhoGEF; Short=FIR; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2; AltName: Full=Pleckstrin homology domain-containing family C member 3; Short=PH domain-containing family C member 3;+++[A0A2X0SSL3_HUMAN|Unreviewed]SubName: Full=FARP2 {ECO:0000313|EMBL:SPT35757.1}; Flags: Fragment;+++[C9JVQ5_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393376}; Flags: Fragment;+++[C9JWM9_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000388167}; Flags: Fragment;+++[H7C210_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000403437}; Flags: Fragment;+++[H7C3E4_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000411353}; Flags: Fragment;+++[H7C3M7_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000412772}; Flags: Fragment;+++[H7C447_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415474}; Flags: Fragment;"]
[9856,"'KIAA0319'",27,17,21,21.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0031901///early endosome membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0007399///nervous system development+++GO:2000171///negative regulation of dendrite development+++GO:0001764///neuron migration+++GO:0007275///multicellular organism development+++GO:0061024///membrane organization","KIAA0319","[K0319_HUMAN|Reviewed]RecName: Full=Dyslexia-associated protein KIAA0319; Flags: Precursor;+++[A0A087X0U9_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319 {ECO:0000313|Ensembl:ENSP00000483665};+++[L8E9P4_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0319 {ECO:0000313|EMBL:CCQ43461.1};"]
[9857,"'CEP350'",400,432,351,394.333333333333,{"$nulls":4},"GO:0005819///spindle+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0034453///microtubule anchoring","centrosomal protein 350","[CE350_HUMAN|Reviewed]RecName: Full=Centrosome-associated protein 350 {ECO:0000305}; Short=Cep350; AltName: Full=Centrosome-associated protein of 350 kDa {ECO:0000303|Ref.1};+++[A0A024R914_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 350kDa, isoform CRA_a {ECO:0000313|EMBL:EAW91073.1};+++[A2A4F6_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000350016}; Flags: Fragment;+++[E9PIK0_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000435808}; Flags: Fragment;+++[H0Y6Q4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000407044}; Flags: Fragment;+++[H0Y7F7_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000412460}; Flags: Fragment;+++[H0YD38_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000432910}; Flags: Fragment;+++[L8ECF2_HUMAN|Unreviewed]SubName: Full=Alternative protein CEP350 {ECO:0000313|EMBL:CCQ43462.1};+++[Q05D72_HUMAN|Unreviewed]SubName: Full=CEP350 protein {ECO:0000313|EMBL:AAH17847.1}; Flags: Fragment;+++[Q5T2X4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000401608}; Flags: Fragment;+++[Q5T2X5_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000409395}; Flags: Fragment;"]
[9858,"'PPP1R26'",482,552,516,516.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding","GO:0010923///negative regulation of phosphatase activity+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","protein phosphatase 1 regulatory subunit 26","[PPR26_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1 regulatory subunit 26;+++[A0A024R8E9_HUMAN|Unreviewed]SubName: Full=KIAA0649, isoform CRA_a {ECO:0000313|EMBL:EAW88151.1};"]
[9859,"'CEP170'",1268,1192,1176,1212,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0120103///centriolar subdistal appendage+++GO:0005819///spindle+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule","GO:0005515///protein binding",null,"centrosomal protein 170","[CE170_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 170 kDa; Short=Cep170; AltName: Full=KARP-1-binding protein; Short=KARP1-binding protein;+++[A6H8X9_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI46791.1};+++[B2RTS4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI40795.1};+++[E5RFU8_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427944}; Flags: Fragment;+++[E5RG47_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427843}; Flags: Fragment;+++[E5RGW7_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430112}; Flags: Fragment;+++[E5RIH6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428400}; Flags: Fragment;+++[E5RJT5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428183}; Flags: Fragment;+++[E7EMW0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427842};+++[E7EWM2_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430142};+++[H0Y2V6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000338161}; Flags: Fragment;+++[H0Y4T4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000394002}; Flags: Fragment;+++[H0YB66_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428777}; Flags: Fragment;+++[H0YB92_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428996}; Flags: Fragment;+++[Q6AZE1_HUMAN|Unreviewed]SubName: Full=CEP170 protein {ECO:0000313|EMBL:AAH78155.1}; Flags: Fragment;"]
[9860,"'LRIG2'",262,288,296.98,282.326666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030426///growth cone+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0097708///intracellular vesicle","GO:0005102///signaling receptor binding","GO:0048681///negative regulation of axon regeneration+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0010640///regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:2001222///regulation of neuron migration+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0048679///regulation of axon regeneration+++GO:0060384///innervation+++GO:0007605///sensory perception of sound","leucine rich repeats and immunoglobulin like domains 2","[LRIG2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 2; Short=LIG-2; Flags: Precursor;"]
[9861,"'PSMD6'",712,609,616,645.666666666667,"03050///Proteasome+++05169///Epstein-Barr virus infection","H00063///Spinocerebellar ataxia (SCA)","M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0005576///extracellular region+++GO:0000502///proteasome complex+++GO:1904813///ficolin-1-rich granule lumen+++GO:0022624///proteasome accessory complex+++GO:0005829///cytosol+++GO:0005838///proteasome regulatory particle+++GO:0034774///secretory granule lumen+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0016887///ATPase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0043687///post-translational protein modification+++GO:0050790///regulation of catalytic activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043312///neutrophil degranulation","proteasome 26S subunit, non-ATPase 6","[PSMD6_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 6; AltName: Full=26S proteasome regulatory subunit RPN7; AltName: Full=26S proteasome regulatory subunit S10; AltName: Full=Breast cancer-associated protein SGA-113M; AltName: Full=Phosphonoformate immuno-associated protein 4; AltName: Full=Proteasome regulatory particle subunit p44S10; AltName: Full=p42A;+++[B3KT66_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, isoform CRA_c {ECO:0000313|EMBL:EAW65426.1}; SubName: Full=cDNA FLJ37740 fis, clone BRHIP2021870, highly similar to 26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|EMBL:BAG52978.1};+++[C9J0E9_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418887}; Flags: Fragment;+++[C9J7B7_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418303}; Flags: Fragment;+++[H7C531_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418843}; Flags: Fragment;"]
[9862,"'MED24'",2148,2204,1994,2115.33333333333,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0042809///vitamin D receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0003712///transcription coregulator activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0038023///signaling receptor activity","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0030521///androgen receptor signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated","mediator complex subunit 24","[MED24_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 24; AltName: Full=Activator-recruited cofactor 100 kDa component; Short=ARC100; AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 4; Short=CRSP complex subunit 4; AltName: Full=Mediator complex subunit 24; AltName: Full=Thyroid hormone receptor-associated protein 4; AltName: Full=Thyroid hormone receptor-associated protein complex 100 kDa component; Short=Trap100; Short=hTRAP100; AltName: Full=Vitamin D3 receptor-interacting protein complex 100 kDa component; Short=DRIP100;+++[A0A0B4J1W0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000377684}; SubName: Full=Thyroid hormone receptor associated protein 4, isoform CRA_a {ECO:0000313|EMBL:EAW60629.1};+++[B4DDR8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463751}; SubName: Full=cDNA FLJ59464, highly similar to Thyroid hormone receptor-associated proteincomplex 100 kDa component {ECO:0000313|EMBL:BAG56829.1};+++[B9TX62_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i2 {ECO:0000313|EMBL:ACB88915.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000393464}; Flags: Fragment;+++[B9TX63_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i3 {ECO:0000313|EMBL:ACB88916.1}; Flags: Fragment;+++[B9TX64_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i4 {ECO:0000313|EMBL:ACB88917.1}; Flags: Fragment;+++[B9TX65_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i5 {ECO:0000313|EMBL:ACB88918.1}; Flags: Fragment;+++[B9TX66_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i6 {ECO:0000313|EMBL:ACB88919.1}; Flags: Fragment;+++[B9TX67_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i7 {ECO:0000313|EMBL:ACB88920.1}; Flags: Fragment;+++[B9TX68_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i8 {ECO:0000313|EMBL:ACB88921.1}; Flags: Fragment;+++[B9TX69_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i9 {ECO:0000313|EMBL:ACB88922.1}; Flags: Fragment;+++[B9TX70_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i10 {ECO:0000313|EMBL:ACB88923.1}; Flags: Fragment;+++[B9TX71_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i11 {ECO:0000313|EMBL:ACB88924.1}; Flags: Fragment;+++[B9TX72_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i12 {ECO:0000313|EMBL:ACB88925.1}; Flags: Fragment;+++[B9TX73_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i13 {ECO:0000313|EMBL:ACB88926.1}; Flags: Fragment;+++[B9TX74_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i14 {ECO:0000313|EMBL:ACB88927.1}; Flags: Fragment;+++[B9TX75_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i15 {ECO:0000313|EMBL:ACB88928.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000482676};+++[B9TX76_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i16 {ECO:0000313|EMBL:ACB88929.1};+++[E9PFL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000392276}; Flags: Fragment;+++[F5GY88_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000440100};+++[F5H0M2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438767}; Flags: Fragment;+++[F5H2D6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438630}; Flags: Fragment;+++[F5H3E6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000439148};+++[F5H5K2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000443344}; Flags: Fragment;+++[H0YEG1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000435760}; Flags: Fragment;+++[J3KSL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462539}; Flags: Fragment;+++[J3KSU0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462646}; Flags: Fragment;+++[J3KTL3_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463043}; Flags: Fragment;+++[J3QLC0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463480}; Flags: Fragment;+++[J3QLC2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463484}; Flags: Fragment;+++[J3QLF8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463528}; Flags: Fragment;+++[J3QLV7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463724}; Flags: Fragment;+++[J3QRH9_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000464225}; Flags: Fragment;"]
[9863,"'MAGI2'",286,309.05,275.16,290.07,"04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway","H01657///Nephrotic syndrome",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005923///bicellular tight junction+++GO:0045202///synapse+++GO:0005768///endosome+++GO:0043005///neuron projection+++GO:0014069///postsynaptic density+++GO:0005770///late endosome+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030425///dendrite","GO:0030159///receptor signaling complex scaffold activity+++GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0070699///type II activin receptor binding+++GO:0070697///activin receptor binding+++GO:0016301///kinase activity+++GO:0046332///SMAD binding","GO:0007399///nervous system development+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0072015///glomerular visceral epithelial cell development+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0030336///negative regulation of cell migration+++GO:0002092///positive regulation of receptor internalization+++GO:0008285///negative regulation of cell proliferation+++GO:0043113///receptor clustering+++GO:0038180///nerve growth factor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0060395///SMAD protein signal transduction+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0071850///mitotic cell cycle arrest+++GO:0007165///signal transduction+++GO:0051291///protein heterooligomerization+++GO:0016310///phosphorylation+++GO:0003402///planar cell polarity pathway involved in axis elongation","membrane associated guanylate kinase, WW and PDZ domain containing 2","[MAGI2_HUMAN|Reviewed]RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; AltName: Full=Atrophin-1-interacting protein 1; Short=AIP-1; AltName: Full=Atrophin-1-interacting protein A; AltName: Full=Membrane-associated guanylate kinase inverted 2; Short=MAGI-2;+++[A0A0D9SET0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000485970};+++[A0A0D9SEY4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486131};+++[A0A0D9SEZ7_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486154}; Flags: Fragment;+++[A0A0D9SF86_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486379}; Flags: Fragment;+++[A0A0D9SFP3_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486774};+++[A0A0D9SFY9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487001}; Flags: Fragment;+++[A0A0D9SGF2_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487435};+++[A0A0D9SGF8_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_c {ECO:0000313|EMBL:EAW77024.1}; SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487448};+++[A0A0D9SGI1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487526};+++[A0A0E3D6M1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000441603};+++[A0A0U1RRH4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489533}; Flags: Fragment;+++[A0A1B0GTC0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489633};+++[A0A1B0GTH8_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489709}; Flags: Fragment;+++[A0A1B0GUF0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490080};+++[A0A1B0GUI9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490128}; Flags: Fragment;+++[A0A1B0GUV4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490259};+++[A0A1B0GVS0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490629}; Flags: Fragment;+++[A0A1B0GVS6_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490637};+++[B7Z4H4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61315, highly similar to Membrane-associated guanylate kinase, WW andPDZ domain-containing protein 2 {ECO:0000313|EMBL:BAH12560.1};+++[D6W5N0_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_b {ECO:0000313|EMBL:EAW77023.1};+++[E7EWI0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000428389};"]
[9865,"'TRIL'",159,299,251,236.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0046696///lipopolysaccharide receptor complex","GO:0001530///lipopolysaccharide binding","GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response+++GO:0002718///regulation of cytokine production involved in immune response","TLR4 interactor with leucine rich repeats","[TRIL_HUMAN|Reviewed]RecName: Full=TLR4 interactor with leucine rich repeats; AltName: Full=Leucine-rich repeat-containing protein KIAA0644; Flags: Precursor;"]
[9866,"'TRIM66'",258,358,292,302.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016235///aggresome","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0045892///negative regulation of transcription, DNA-templated","tripartite motif containing 66","[TRI66_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 66;+++[A0A2R8YE93_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000494157}; Flags: Fragment;+++[A0A2R8YEA1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000495413};+++[B5MCJ9_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000384876};+++[H0YF52_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000437234}; Flags: Fragment;"]
[9867,"'PJA2'",1332,1382,1257,1323.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045202///synapse+++GO:0005783///endoplasmic reticulum+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0045111///intermediate filament cytoskeleton+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm","GO:0034236///protein kinase A catalytic subunit binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity","GO:0006954///inflammatory response+++GO:0035329///hippo signaling+++GO:0016567///protein ubiquitination+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0045087///innate immune response+++GO:0043030///regulation of macrophage activation+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0010738///regulation of protein kinase A signaling+++GO:0007616///long-term memory","praja ring finger ubiquitin ligase 2","[PJA2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Praja-2; Short=Praja2; EC=2.3.2.27; AltName: Full=RING finger protein 131; AltName: Full=RING-type E3 ubiquitin transferase Praja-2 {ECO:0000305};"]
[9868,"'TOMM70'",781,742,636,719.666666666667,{"$nulls":4},"GO:0005742///mitochondrial outer membrane translocase complex+++GO:0070062///extracellular exosome+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding","GO:0071806///protein transmembrane transport+++GO:0006626///protein targeting to mitochondrion","translocase of outer mitochondrial membrane 70","[TOM70_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM70; AltName: Full=Mitochondrial precursor proteins import receptor; AltName: Full=Translocase of outer membrane 70 kDa subunit; AltName: Full=Translocase of outer mitochondrial membrane protein 70 {ECO:0000312|HGNC:HGNC:11985};"]
[9869,"'SETDB1'",599,694,620,637.666666666667,"04550///Signaling pathways regulating pluripotency of stem cells+++00310///Lysine degradation",null,null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm","GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:1990841///promoter-specific chromatin binding+++GO:0016740///transferase activity","GO:0045471///response to ethanol+++GO:0032259///methylation+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0006325///chromatin organization+++GO:0033273///response to vitamin+++GO:0007265///Ras protein signal transduction+++GO:0034968///histone lysine methylation","SET domain bifurcated 1","[SETB1_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETDB1; EC=2.1.1.43; AltName: Full=ERG-associated protein with SET domain; Short=ESET; AltName: Full=Histone H3-K9 methyltransferase 4; Short=H3-K9-HMTase 4; AltName: Full=Lysine N-methyltransferase 1E; AltName: Full=SET domain bifurcated 1;+++[B0QZE6_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000409379}; Flags: Fragment;+++[E9PAP1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357960};+++[E9PQM8_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000436148}; Flags: Fragment;+++[E9PRF4_HUMAN|Unreviewed]RecName: Full=Histone-lysine N-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00906}; EC=2.1.1.43 {ECO:0000256|PROSITE-ProRule:PRU00906}; Flags: Fragment;+++[E9PS59_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000435922}; Flags: Fragment;+++[X6R732_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357959};+++[X6RHV1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000407831}; Flags: Fragment;"]
[987,"'LRBA'",1137,1272,1282,1230.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0008150///biological_process","LPS responsive beige-like anchor protein","[LRBA_HUMAN|Reviewed]RecName: Full=Lipopolysaccharide-responsive and beige-like anchor protein; AltName: Full=Beige-like protein; AltName: Full=CDC4-like protein;+++[E9PEM5_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000422180};+++[H0Y9N9_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000424640}; Flags: Fragment;+++[H0YA17_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000425852}; Flags: Fragment;+++[H0YAC6_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000426669}; Flags: Fragment;+++[Q6P1X2_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH64834.1};+++[Q969R7_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH12535.2}; Flags: Fragment;"]
[9870,"'AREL1'",1089,1095,979,1054.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0006915///apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process","apoptosis resistant E3 ubiquitin protein ligase 1","[AREL1_HUMAN|Reviewed]RecName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1; EC=2.3.2.26; AltName: Full=Apoptosis-resistant HECT-type E3 ubiquitin transferase 1;+++[G3V245_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450458}; Flags: Fragment;+++[G3V2B5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450557};+++[G3V506_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452101}; Flags: Fragment;+++[G3V5P7_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452456};+++[H0YJ67_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450901}; Flags: Fragment;+++[H0YJ69_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450912}; Flags: Fragment;+++[H0YJF1_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451375}; Flags: Fragment;+++[H0YJK5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451710}; Flags: Fragment;+++[L8E7E7_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0317 {ECO:0000313|EMBL:CCQ43054.1};"]
[9871,"'SEC24D'",618,643,735,665.333333333333,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0030127///COPII vesicle coat+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum","GO:0000149///SNARE binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0090110///cargo loading into COPII-coated vesicle+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0016192///vesicle-mediated transport+++GO:0001701///in utero embryonic development+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I","SEC24 homolog D, COPII coat complex component","[SC24D_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24D {ECO:0000305}; AltName: Full=SEC24-related protein D;+++[A8K6V0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78676, highly similar to Homo sapiens SEC24 related gene family, member D (SEC24D), mRNA {ECO:0000313|EMBL:BAF84454.1};+++[D6RAE2_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000422717};+++[D6RBM1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000424085};+++[D6RGJ5_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000426309}; Flags: Fragment;+++[E9PC44_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43974 fis, clone TESTI4018101, highly similar to Protein transport protein Sec24D {ECO:0000313|EMBL:BAG54271.1};+++[E9PDM8_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000425491};+++[E9PG84_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000427249};+++[Q49AI3_HUMAN|Unreviewed]SubName: Full=SEC24D protein {ECO:0000313|EMBL:AAH37736.1};+++[Q4W5D3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEC24D {ECO:0000313|EMBL:AAY40935.1}; Flags: Fragment;"]
[9873,"'FCHSD2'",279,243,272,264.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0055037///recycling endosome","GO:0005515///protein binding","GO:0007274///neuromuscular synaptic transmission+++GO:0030833///regulation of actin filament polymerization","FCH and double SH3 domains 2","[FCSD2_HUMAN|Reviewed]RecName: Full=F-BAR and double SH3 domains protein 2; AltName: Full=Carom; AltName: Full=SH3 multiple domains protein 3;+++[A0A024R5H2_HUMAN|Unreviewed]SubName: Full=FCH and double SH3 domains 2, isoform CRA_a {ECO:0000313|EMBL:EAW74881.1};+++[B8ZZW8_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386903};+++[C9JM66_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000408706}; Flags: Fragment;+++[E7ENZ2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000402972};+++[E9PG19_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386987};+++[H0Y6M2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000406420}; Flags: Fragment;+++[H0YG35_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000441616}; Flags: Fragment;"]
[9874,"'TLK1'",795,927,820,847.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006325///chromatin organization+++GO:0001672///regulation of chromatin assembly or disassembly+++GO:0007049///cell cycle+++GO:0006886///intracellular protein transport","tousled like kinase 1","[TLK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase tousled-like 1; EC=2.7.11.1; AltName: Full=PKU-beta; AltName: Full=Tousled-like kinase 1;+++[B3KRP1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000387313}; SubName: Full=Tousled-like kinase 1, isoform CRA_b {ECO:0000313|EMBL:EAX11221.1}; SubName: Full=cDNA FLJ34656 fis, clone KIDNE2018352, highly similar to Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|EMBL:BAG52453.1};+++[C9JWT6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000393165}; Flags: Fragment;+++[F8W7X8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000352810};+++[Q53TE4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAY15077.1}; Flags: Fragment;+++[Q53TF9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAX93162.1}; Flags: Fragment;"]
[9875,"'URB1'",752,930,887,856.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0008150///biological_process+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","URB1 ribosome biogenesis homolog","[NPA1P_HUMAN|Reviewed]RecName: Full=Nucleolar pre-ribosomal-associated protein 1; AltName: Full=Nucleolar protein 254 kDa; AltName: Full=URB1 ribosome biogenesis 1 homolog;"]
[9877,"'ZC3H11A'",1782.72,1786.83,1721.85,1763.8,{"$nulls":4},"GO:0000346///transcription export complex+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003729///mRNA binding","GO:0006405///RNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031124///mRNA 3'-end processing+++GO:0051028///mRNA transport","zinc finger CCCH-type containing 11A","[ZC11A_HUMAN|Reviewed]RecName: Full=Zinc finger CCCH domain-containing protein 11A;+++[A0A1W2PPR9_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000491483};+++[C9J0L0_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000406531}; Flags: Fragment;+++[E9PBY7_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000415072}; Flags: Fragment;+++[E9PQ61_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000432602};+++[Q0D2N5_HUMAN|Unreviewed]SubName: Full=ZC3H11A protein {ECO:0000313|EMBL:AAH46137.1};"]
[9878,"'TOX4'",1347,1397.91,1237,1327.30333333333,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0030175///filopodium+++GO:0031225///anchored component of membrane+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0005576///extracellular region+++GO:0042995///cell projection+++GO:0032432///actin filament bundle+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0042627///chylomicron+++GO:0001891///phagocytic cup+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0032587///ruffle membrane+++GO:0002102///podosome+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0015629///actin cytoskeleton+++GO:0000785///chromatin+++GO:0034361///very-low-density lipoprotein particle+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0001726///ruffle","GO:0008201///heparin binding+++GO:0004806///triglyceride lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003779///actin binding+++GO:0051020///GTPase binding+++GO:0004465///lipoprotein lipase activity+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0034185///apolipoprotein binding+++GO:0051015///actin filament binding+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0004620///phospholipase activity+++GO:0017129///triglyceride binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding","GO:0051639///actin filament network formation+++GO:0050729///positive regulation of inflammatory response+++GO:0022617///extracellular matrix disassembly+++GO:0019433///triglyceride catabolic process+++GO:0031100///animal organ regeneration+++GO:0006641///triglyceride metabolic process+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0044319///wound healing, spreading of cells+++GO:0006644///phospholipid metabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0070328///triglyceride homeostasis+++GO:0016477///cell migration+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0002286///T cell activation involved in immune response+++GO:0009409///response to cold+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0010737///protein kinase A signaling+++GO:0071803///positive regulation of podosome assembly+++GO:0034371///chylomicron remodeling+++GO:0006633///fatty acid biosynthetic process+++GO:0033157///regulation of intracellular protein transport+++GO:0016042///lipid catabolic process+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0090197///positive regulation of chemokine secretion+++GO:0042632///cholesterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0009617///response to bacterium+++GO:0042493///response to drug+++GO:0009749///response to glucose+++GO:0010886///positive regulation of cholesterol storage+++GO:0051017///actin filament bundle assembly+++GO:0006357///regulation of transcription by RNA polymerase II","TOX high mobility group box family member 4","[TOX4_HUMAN|Reviewed]RecName: Full=TOX high mobility group box family member 4; AltName: Full=Epidermal Langerhans cell protein LCP1;+++[C9J919_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000406196}; Flags: Fragment;+++[C9JNL1_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000402195}; Flags: Fragment;+++[F8WBE8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000389333};+++[F8WC04_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392234};+++[F8WCL8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392482};+++[Q5TBN3_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000408052}; Flags: Fragment;+++[Q5TBN5_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000402157}; Flags: Fragment;"]
[9879,"'DDX46'",843,855,720,806,"03040///Spliceosome",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","DEAD-box helicase 46","[DDX46_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX46; EC=3.6.4.13; AltName: Full=DEAD box protein 46; AltName: Full=PRP5 homolog;+++[A0A0C4DG89_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000416534};+++[D3DQA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_a {ECO:0000313|EMBL:EAW62242.1};+++[D6RJA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_b {ECO:0000313|EMBL:EAW62239.1}; SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000427290};+++[H0Y9U3_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000425073}; Flags: Fragment;+++[H0YAD5_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000426767}; Flags: Fragment;+++[Q0VGL8_HUMAN|Unreviewed]SubName: Full=DDX46 protein {ECO:0000313|EMBL:AAI05599.1}; Flags: Fragment;"]
[988,"'CDC5L'",676,775.41,682,711.136666666667,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0016020///membrane+++GO:0000974///Prp19 complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005662///DNA replication factor A complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0016607///nuclear speck+++GO:0032993///protein-DNA complex+++GO:0071013///catalytic step 2 spliceosome","GO:0001222///transcription corepressor binding+++GO:0008157///protein phosphatase 1 binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0043522///leucine zipper domain binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0071987///WD40-repeat domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0000278///mitotic cell cycle+++GO:0000398///mRNA splicing, via spliceosome+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0008380///RNA splicing+++GO:0006974///cellular response to DNA damage stimulus+++GO:1904568///cellular response to wortmannin+++GO:0072422///signal transduction involved in DNA damage checkpoint+++GO:0007049///cell cycle+++GO:0071352///cellular response to interleukin-2+++GO:1990646///cellular response to prolactin+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006397///mRNA processing","cell division cycle 5 like","[CDC5L_HUMAN|Reviewed]RecName: Full=Cell division cycle 5-like protein; Short=Cdc5-like protein; AltName: Full=Pombe cdc5-related protein;"]
[9880,"'ZBTB39'",163,190,171,174.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 39","[ZBT39_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 39;"]
[9881,"'TRANK1'",236,292,217,248.333333333333,{"$nulls":5},"GO:0005524///ATP binding",null,"tetratricopeptide repeat and ankyrin repeat containing 1","[TRNK1_HUMAN|Reviewed]RecName: Full=TPR and ankyrin repeat-containing protein 1; AltName: Full=Lupus brain antigen 1 homolog;+++[A0A096LPF5_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000485569}; Flags: Fragment;+++[A0A2R8Y7N6_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496256}; Flags: Fragment;+++[A0A2R8Y890_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496740}; Flags: Fragment;+++[A0A2R8Y8A3_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496771};+++[A0A2R8YEM9_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000494480};+++[L8EAQ6_HUMAN|Unreviewed]SubName: Full=Alternative protein TRANK1 {ECO:0000313|EMBL:CCQ43463.1};"]
[9882,"'TBC1D4'",55,57,66,59.3333333333333,"04931///Insulin resistance+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031982///vesicle+++GO:0005829///cytosol","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0016192///vesicle-mediated transport+++GO:0032869///cellular response to insulin stimulus+++GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport+++GO:0031339///negative regulation of vesicle fusion+++GO:0043547///positive regulation of GTPase activity","TBC1 domain family member 4","[TBCD4_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 4; AltName: Full=Akt substrate of 160 kDa; Short=AS160;+++[A0A024R637_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW80538.1};+++[Q5JU47_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 4 {ECO:0000313|Ensembl:ENSP00000396932}; Flags: Fragment;"]
[9883,"'POM121'",3801.99,4420.66,4075.81,4099.48666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0032389///MutLalpha complex","GO:0008139///nuclear localization sequence binding+++GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0017056///structural constituent of nuclear pore+++GO:0046872///metal ion binding","GO:0006606///protein import into nucleus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0016032///viral process+++GO:0006310///DNA recombination+++GO:0006298///mismatch repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus","POM121 transmembrane nucleoporin","[P121A_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;"]
[9884,"'LRRC37A'",91.75,130.53,116.92,113.066666666667,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0030496///midbody","GO:0044877///protein-containing complex binding+++GO:0016887///ATPase activity+++GO:0017075///syntaxin-1 binding+++GO:0042623///ATPase activity, coupled+++GO:0000149///SNARE binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding","GO:0006813///potassium ion transport+++GO:0035494///SNARE complex disassembly+++GO:0015031///protein transport","leucine rich repeat containing 37A","[L37A1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 37A; Flags: Precursor;"]
[9885,"'OSBPL2'",592.95,611,517,573.65,"05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04151///PI3K-Akt signaling pathway+++01100///Metabolic pathways+++05200///Pathways in cancer+++05146///Amoebiasis+++05145///Toxoplasmosis+++05165///Human papillomavirus infection+++04510///Focal adhesion","H00586///Epidermolysis bullosa, junctional+++H00813///Laryngo onycho cutaneous syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0015248///sterol transporter activity+++GO:0005515///protein binding+++GO:0032934///sterol binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding","GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0006699///bile acid biosynthetic process","oxysterol binding protein like 2","[OSBL2_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 2; Short=ORP-2; Short=OSBP-related protein 2;+++[A0A087WTV1_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000478158}; Flags: Fragment;+++[A0A087WVV0_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000479702}; Flags: Fragment;+++[A0A2R8Y362_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;+++[A0A2R8Y429_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000493721};+++[A0A2R8Y5B9_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000494692};+++[A0A2R8Y5R1_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y690_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y703_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495611};+++[A0A2R8YD49_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YDU7_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YEX0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YFT0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG53_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495661}; Flags: Fragment;+++[A0A2R8YG59_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG95_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[B4DKJ8_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[E7ET92_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[H0Y7X4_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;"]
[9886,"'RHOBTB1'",657,530,547,578,"04120///Ubiquitin mediated proteolysis","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding","GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0043652///engulfment of apoptotic cell+++GO:0016477///cell migration+++GO:0007264///small GTPase mediated signal transduction+++GO:0000902///cell morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho related BTB domain containing 1","[RHBT1_HUMAN|Reviewed]RecName: Full=Rho-related BTB domain-containing protein 1;+++[A0A024QZL4_HUMAN|Unreviewed]SubName: Full=Rho-related BTB domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW54216.1};+++[Q567T3_HUMAN|Unreviewed]SubName: Full=RHOBTB1 protein {ECO:0000313|EMBL:AAH93035.1};"]
[9887,"'SMG7'",1290,1481,1365,1378.66666666667,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton","GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0004540///ribonuclease activity+++GO:0070034///telomerase RNA binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0051721///protein phosphatase 2A binding","GO:0007004///telomere maintenance via telomerase+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0035303///regulation of dephosphorylation+++GO:0043487///regulation of RNA stability+++GO:0006406///mRNA export from nucleus","SMG7, nonsense mediated mRNA decay factor","[SMG7_HUMAN|Reviewed]RecName: Full=Protein SMG7; AltName: Full=EST1-like protein C; AltName: Full=SMG-7 homolog; Short=hSMG-7;+++[B1ALB4_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000388390}; Flags: Fragment;+++[D6R9J3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422056}; Flags: Fragment;+++[D6RAD0_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422742}; Flags: Fragment;+++[E9PBK2_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000400220};+++[E9PD50_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000356507};+++[E9PEK3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000410254};+++[Q6TV06_HUMAN|Unreviewed]SubName: Full=Breast cancer-associated antigen SGA-56M {ECO:0000313|EMBL:AAR25620.1}; SubName: Full=Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), isoform CRA_a {ECO:0000313|EMBL:EAW91154.1};"]
[9889,"'ZBED4'",553,610,549,570.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger BED-type containing 4","[ZBED4_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 4;"]
[989,"'SEPT7'",1306,1121,1014,1147,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016324///apical plasma membrane+++GO:0000775///chromosome, centromeric region+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0031105///septin complex+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0097730///non-motile cilium+++GO:0005634///nucleus+++GO:0031514///motile cilium+++GO:0005930///axoneme+++GO:0032160///septin filament array+++GO:0097227///sperm annulus+++GO:0032154///cleavage furrow+++GO:0001725///stress fiber+++GO:0005929///cilium+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0005198///structural molecule activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding","GO:0051301///cell division+++GO:0016476///regulation of embryonic cell shape+++GO:0000281///mitotic cytokinesis+++GO:0051291///protein heterooligomerization+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0060271///cilium assembly+++GO:0030154///cell differentiation+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:0000921///septin ring assembly","septin 7","[SEPT7_HUMAN|Reviewed]RecName: Full=Septin-7; AltName: Full=CDC10 protein homolog;+++[A0A023T695_HUMAN|Unreviewed]SubName: Full=Septin 7 variant 4 {ECO:0000313|EMBL:AHX84171.1};+++[A0A024RA87_HUMAN|Unreviewed]SubName: Full=Septin 7, isoform CRA_a {ECO:0000313|EMBL:EAW94060.1};+++[A0A0U1RQW0_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489192}; Flags: Fragment;+++[A0A0U1RRD1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489466}; Flags: Fragment;+++[A0A0U1RRE1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489480}; Flags: Fragment;+++[A0A0U1RRH9_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489538}; Flags: Fragment;+++[A0A0U1RRM2_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489596}; Flags: Fragment;+++[A8K3D0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75185 {ECO:0000313|EMBL:BAF83234.1};+++[B4DNE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52574, highly similar to Septin-7 {ECO:0000313|EMBL:BAG60206.1};+++[E7EPK1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000344868};+++[E7ES33_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000381993};+++[G3V1Q4_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000413507};+++[Q3B7A3_HUMAN|Unreviewed]SubName: Full=SEPT7 protein {ECO:0000313|EMBL:AAI07719.1}; Flags: Fragment;+++[Q5JXL7_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000444240};+++[Q8TC62_HUMAN|Unreviewed]SubName: Full=Septin 7 {ECO:0000313|EMBL:AAH25987.3};"]
[9890,"'PLPPR4'",2,2,5,3,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099061///integral component of postsynaptic density membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0016791///phosphatase activity+++GO:0016787///hydrolase activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0042577///lipid phosphatase activity","GO:0007409///axonogenesis+++GO:0046839///phospholipid dephosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0048839///inner ear development+++GO:0006644///phospholipid metabolic process","phospholipid phosphatase related 4","[PLPR4_HUMAN|Reviewed]RecName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000305}; EC=3.1.3.4; AltName: Full=Brain-specific phosphatidic acid phosphatase-like protein 1 {ECO:0000303|Ref.7}; AltName: Full=Lipid phosphate phosphatase-related protein type 4 {ECO:0000303|Ref.2}; AltName: Full=Plasticity-related gene 1 protein {ECO:0000305|PubMed:12730698}; Short=PRG-1 {ECO:0000303|PubMed:12730698};+++[Q3ZCT6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH41386.1}; Flags: Fragment;+++[Q86XM6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH42963.1}; Flags: Fragment;+++[W4VSQ3_HUMAN|Unreviewed]SubName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000313|Ensembl:ENSP00000359203};"]
[9891,"'NUAK1'",970,717,783,823.333333333333,{"$nulls":4},"GO:0001650///fibrillar center+++GO:0015630///microtubule cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0002039///p53 binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0042127///regulation of cell proliferation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0007155///cell adhesion+++GO:0030155///regulation of cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035507///regulation of myosin-light-chain-phosphatase activity+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000772///regulation of cellular senescence","NUAK family kinase 1","[NUAK1_HUMAN|Reviewed]RecName: Full=NUAK family SNF1-like kinase 1; EC=2.7.11.1; AltName: Full=AMPK-related protein kinase 5; Short=ARK5; AltName: Full=Omphalocele kinase 1;+++[A0A024RBL3_HUMAN|Unreviewed]SubName: Full=NUAK family, SNF1-like kinase, 1, isoform CRA_a {ECO:0000313|EMBL:EAW97769.1};+++[F8VSH4_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000448288}; Flags: Fragment;+++[F8VXF0_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000449990}; Flags: Fragment;+++[F8VZ96_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000446873}; Flags: Fragment;"]
[9892,"'SNAP91'",115,107,107,109.666666666667,{"$nulls":4},"GO:0030136///clathrin-coated vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005905///clathrin-coated pit","GO:0030276///clathrin binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0019901///protein kinase binding","GO:0048268///clathrin coat assembly+++GO:0015031///protein transport+++GO:2000369///regulation of clathrin-dependent endocytosis","synaptosome associated protein 91","[AP180_HUMAN|Reviewed]RecName: Full=Clathrin coat assembly protein AP180; AltName: Full=91 kDa synaptosomal-associated protein; AltName: Full=Clathrin coat-associated protein AP180; AltName: Full=Phosphoprotein F1-20;+++[A0A0A0MRM7_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358705}; Flags: Fragment;+++[B7Z2N2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57108, highly similar to Clathrin coat assembly protein AP180 {ECO:0000313|EMBL:BAH11918.1};+++[E5RFC6_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358704}; Flags: Fragment;+++[E5RFU0_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000427959}; Flags: Fragment;+++[E5RGP8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429950};+++[E5RGY9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430071}; Flags: Fragment;+++[E5RHK9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429700};+++[E5RIJ5_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429429}; Flags: Fragment;+++[E5RJY3_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000431055}; Flags: Fragment;+++[E5RK51_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430441}; Flags: Fragment;+++[E5RK53_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000428127};+++[E9PDG8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429776};+++[H0UI15_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein, 91kDa homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW48659.1};+++[H0YBT2_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430255}; Flags: Fragment;"]
[9894,"'TELO2'",643,695,696,678,"04150///mTOR signaling pathway+++03460///Fanconi anemia pathway","H01789///You-Hoover-Fong syndrome",null,null,"GO:0000784///nuclear chromosome, telomeric region+++GO:0034399///nuclear periphery+++GO:0005622///intracellular+++GO:0031932///TORC2 complex+++GO:0016607///nuclear speck+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0031931///TORC1 complex+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0070209///ASTRA complex","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004713///protein tyrosine kinase activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0042162///telomeric DNA binding+++GO:0051879///Hsp90 protein binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:1904263///positive regulation of TORC1 signaling+++GO:0000723///telomere maintenance+++GO:0032526///response to retinoic acid+++GO:1904515///positive regulation of TORC2 signaling+++GO:0006468///protein phosphorylation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0032006///regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation+++GO:0010033///response to organic substance+++GO:0010212///response to ionizing radiation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0071902///positive regulation of protein serine/threonine kinase activity","telomere maintenance 2","[TELO2_HUMAN|Reviewed]RecName: Full=Telomere length regulation protein TEL2 homolog; AltName: Full=Protein clk-2 homolog; Short=hCLK2;+++[B4DXS2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58340 {ECO:0000313|EMBL:BAG63484.1};+++[H3BRS3_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000456383};+++[H3BU45_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000457461}; Flags: Fragment;+++[Q9BRG8_HUMAN|Unreviewed]SubName: Full=CLK2 protein {ECO:0000313|EMBL:AAH06274.2}; Flags: Fragment;"]
[9895,"'TECPR2'",1377,1764,1541,1560.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005515///protein binding","GO:0006914///autophagy","tectonin beta-propeller repeat containing 2","[TCPR2_HUMAN|Reviewed]RecName: Full=Tectonin beta-propeller repeat-containing protein 2; AltName: Full=WD repeat-containing protein KIAA0329/KIAA0297;+++[L8E8K7_HUMAN|Unreviewed]SubName: Full=Alternative protein TECPR2 {ECO:0000313|EMBL:CCQ43464.1};"]
[9896,"'FIG4'",390,340,318,349.333333333333,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase ATP + dCDP <=> ADP + dCTP+++R00156///ATP:UDP phosphotransferase ATP + UDP <=> ADP + UTP+++R00722///ATP:IDP phosphotransferase ATP + IDP <=> ADP + ITP+++R02093///ATP:dTDP phosphotransferase ATP + dTDP <=> ADP + dTTP+++R01547///ATP:dAMP phosphotransferase ATP + dAMP <=> ADP + dADP+++R00330///ATP:GDP phosphotransferase ATP + GDP <=> ADP + GTP+++R00570///ATP:CDP phosphotransferase ATP + CDP <=> ADP + CTP+++R00124///ATP:ADP phosphatransferase ATP + ADP <=> ADP + ATP+++R03530///ATP:dIDP phosphotransferase ATP + dIDP <=> ADP + dITP+++R00127///ATP:AMP phosphotransferase ATP + AMP <=> 2 ADP+++R01857///ATP:dGDP phosphotransferase ATP + dGDP <=> ADP + dGTP+++R02331///ATP:dUDP phosphotransferase ATP + dUDP <=> ADP + dUTP+++R01137///ATP:dADP phosphotransferase ATP + dADP <=> ADP + dATP","GO:0043231///intracellular membrane-bounded organelle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0010008///endosome membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005811///lipid droplet+++GO:0055037///recycling endosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0042578///phosphoric ester hydrolase activity+++GO:0034593///phosphatidylinositol bisphosphate phosphatase activity+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0043813///phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity","GO:0046488///phosphatidylinositol metabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0007626///locomotory behavior+++GO:0032288///myelin assembly+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0048666///neuron development+++GO:0016311///dephosphorylation+++GO:0031642///negative regulation of myelination+++GO:0007033///vacuole organization+++GO:0043473///pigmentation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process","FIG4 phosphoinositide 5-phosphatase","[FIG4_HUMAN|Reviewed]RecName: Full=Polyphosphoinositide phosphatase; EC=3.1.3.-; AltName: Full=Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; AltName: Full=SAC domain-containing protein 3;+++[H0Y6G7_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000405660}; Flags: Fragment;+++[Q5JRV4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000396566}; Flags: Fragment;+++[Q5TCS4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000357937};+++[Q5TCS5_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000412156}; Flags: Fragment;"]
[9897,"'WASHC5'",1003,947,886,945.333333333333,"04144///Endocytosis","H00266///Hereditary spastic paraplegia (SPG)+++H01568///3C syndrome",null,null,"GO:0005768///endosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005769///early endosome+++GO:0071203///WASH complex+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0001556///oocyte maturation+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0010976///positive regulation of neuron projection development+++GO:0090306///spindle assembly involved in meiosis+++GO:0015031///protein transport+++GO:0016197///endosomal transport","WASH complex subunit 5","[WASC5_HUMAN|Reviewed]RecName: Full=WASH complex subunit 5 {ECO:0000312|HGNC:HGNC:28984}; AltName: Full=Strumpellin; AltName: Full=WASH complex subunit strumpellin {ECO:0000305};+++[E5RFU6_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000427946}; Flags: Fragment;+++[E7EQI7_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000429676};"]
[9898,"'UBAP2L'",5881,6410,5834,6041.66666666667,null,"H00100///Neutropenic disorders",null,null,"GO:0031519///PcG protein complex+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0007339///binding of sperm to zona pellucida+++GO:0061484///hematopoietic stem cell homeostasis","ubiquitin associated protein 2 like","[UBP2L_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated protein 2-like; AltName: Full=Protein NICE-4;+++[B4DYY5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55671, highly similar to Ubiquitin-associated protein 2-like {ECO:0000313|EMBL:BAG63897.1};+++[F8W726_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000271877};+++[H0Y5H6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000398609}; Flags: Fragment;+++[H7C2T8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000407672}; Flags: Fragment;+++[Q5VU77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000357490}; Flags: Fragment;+++[Q5VU78_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389052}; Flags: Fragment;+++[Q5VU79_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389717}; Flags: Fragment;+++[Q5VU80_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000415310}; Flags: Fragment;+++[Q5VU81_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000399920}; Flags: Fragment;"]
[9899,"'SV2B'",12,16.97,9,12.6566666666667,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0030672///synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction","GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0022857///transmembrane transporter activity","GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport+++GO:0006836///neurotransmitter transport","synaptic vesicle glycoprotein 2B","[SV2B_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2B;"]
[990,"'CDC6'",31,23,41,31.6666666666667,"04110///Cell cycle+++04111///Cell cycle - yeast+++04113///Meiosis - yeast","H01889///Meier-Gorlin syndrome",null,null,"GO:0005634///nucleus+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0051233///spindle midzone+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006270///DNA replication initiation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0051984///positive regulation of chromosome segregation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1904385///cellular response to angiotensin+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0032467///positive regulation of cytokinesis+++GO:0033314///mitotic DNA replication checkpoint+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0007089///traversing start control point of mitotic cell cycle+++GO:0000076///DNA replication checkpoint+++GO:1904117///cellular response to vasopressin+++GO:0006260///DNA replication+++GO:0051301///cell division+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000278///mitotic cell cycle","cell division cycle 6","[CDC6_HUMAN|Reviewed]RecName: Full=Cell division control protein 6 homolog; AltName: Full=CDC6-related protein; AltName: Full=Cdc18-related protein; Short=HsCdc18; AltName: Full=p62(cdc6); Short=HsCDC6;+++[A0A024R1S2_HUMAN|Unreviewed]RecName: Full=Cell division control protein {ECO:0000256|PIRNR:PIRNR001767};+++[J3KTI7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463004}; Flags: Fragment;+++[J3QLN7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463635}; Flags: Fragment;+++[J3QR52_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000464047}; Flags: Fragment;"]
[9900,"'SV2A'",458,443,468,456.333333333333,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0048786///presynaptic active zone+++GO:0045202///synapse+++GO:0098982///GABA-ergic synapse+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0098978///glutamatergic synapse+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030672///synaptic vesicle membrane+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0043005///neuron projection+++GO:0030425///dendrite","GO:0005215///transporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0014052///regulation of gamma-aminobutyric acid secretion+++GO:0006874///cellular calcium ion homeostasis+++GO:0006836///neurotransmitter transport+++GO:0007268///chemical synaptic transmission+++GO:0016082///synaptic vesicle priming","synaptic vesicle glycoprotein 2A","[SV2A_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2A;+++[B4E000_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57689, highly similar to Synaptic vesicle glycoprotein 2A {ECO:0000313|EMBL:BAG64262.1};+++[L8E840_HUMAN|Unreviewed]SubName: Full=Alternative protein SV2A {ECO:0000313|EMBL:CCQ43465.1};"]
[9901,"'SRGAP3'",239,345,327,303.666666666667,"04360///Axon guidance",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005730///nucleolus","GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0016423///tRNA (guanine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0032197///transposition, RNA-mediated+++GO:0030488///tRNA methylation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","SLIT-ROBO Rho GTPase activating protein 3","[SRGP3_HUMAN|Reviewed]RecName: Full=SLIT-ROBO Rho GTPase-activating protein 3; Short=srGAP3; AltName: Full=Mental disorder-associated GAP; AltName: Full=Rho GTPase-activating protein 14; AltName: Full=WAVE-associated Rac GTPase-activating protein; Short=WRP;"]
[9902,"'MRC2'",1529,1431,1435,1465,"04145///Phagosome+++05152///Tuberculosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005518///collagen binding","GO:0030574///collagen catabolic process+++GO:0001649///osteoblast differentiation+++GO:0006897///endocytosis","mannose receptor C type 2","[MRC2_HUMAN|Reviewed]RecName: Full=C-type mannose receptor 2; AltName: Full=C-type lectin domain family 13 member E; AltName: Full=Endocytic receptor 180; AltName: Full=Macrophage mannose receptor 2; AltName: Full=Urokinase-type plasminogen activator receptor-associated protein; Short=UPAR-associated protein; Short=Urokinase receptor-associated protein; AltName: CD_antigen=CD280; Flags: Precursor;+++[E7EME3_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000400445};+++[J3KRF1_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000461968}; Flags: Fragment;+++[J3QQZ6_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000463968}; Flags: Fragment;"]
[9903,"'KLHL21'",2139,2206,1994,2113,{"$nulls":4},"GO:0005819///spindle+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005827///polar microtubule","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0035853///chromosome passenger complex localization to spindle midzone+++GO:0032465///regulation of cytokinesis+++GO:0016567///protein ubiquitination","kelch like family member 21","[KLH21_HUMAN|Reviewed]RecName: Full=Kelch-like protein 21;+++[K7ELI0_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466089};+++[K7EMF2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466479};+++[K7ESH2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000468710}; Flags: Fragment;+++[L8E9P8_HUMAN|Unreviewed]SubName: Full=Alternative protein KLHL21 {ECO:0000313|EMBL:CCQ43466.1};+++[Q2NKK7_HUMAN|Unreviewed]SubName: Full=KLHL21 protein {ECO:0000313|EMBL:AAI11767.1}; SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000480631};"]
[9904,"'RBM19'",531,594,571,565.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0045292///mRNA cis splicing, via spliceosome+++GO:0040019///positive regulation of embryonic development+++GO:0007275///multicellular organism development+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 19","[RBM19_HUMAN|Reviewed]RecName: Full=Probable RNA-binding protein 19; AltName: Full=RNA-binding motif protein 19;+++[A0A024RBL4_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 19, isoform CRA_a {ECO:0000313|EMBL:EAW98063.1};+++[H0YIL2_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein 19 {ECO:0000313|Ensembl:ENSP00000449604}; Flags: Fragment;"]
[9905,"'SGSM2'",3200,3428,3175,3267.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0042470///melanosome","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:0034499///late endosome to Golgi transport+++GO:0090630///activation of GTPase activity+++GO:0043547///positive regulation of GTPase activity","small G protein signaling modulator 2","[SGSM2_HUMAN|Reviewed]RecName: Full=Small G protein signaling modulator 2; AltName: Full=RUN and TBC1 domain-containing protein 1;+++[B9A6J3_HUMAN|Unreviewed]SubName: Full=RUN and TBC1 domain-containing protein 1 {ECO:0000313|EMBL:BAH16621.1};+++[I3L1Y7_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000459218};+++[I3L361_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000460205}; Flags: Fragment;+++[I3NI18_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000461820}; Flags: Fragment;+++[J3QSA2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000464593}; Flags: Fragment;+++[V9GYD2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476637}; Flags: Fragment;+++[V9GYJ0_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476800};"]
[9906,"'SLC35E2A'",825.47,824.35,805.98,818.6,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0006468///protein phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0006915///apoptotic process+++GO:0050684///regulation of mRNA processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0001558///regulation of cell growth","solute carrier family 35 member E2A","[S35E2_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member E2;"]
[9907,"'AP5Z1'",863.55,943.88,902.18,903.203333333333,null,"H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005634///nucleus+++GO:0044599///AP-5 adaptor complex+++GO:0005737///cytoplasm+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006974///cellular response to DNA damage stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0015031///protein transport+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0016197///endosomal transport","adaptor related protein complex 5 subunit zeta 1","[AP5Z1_HUMAN|Reviewed]RecName: Full=AP-5 complex subunit zeta-1; AltName: Full=Adaptor-related protein complex 5 zeta subunit; Short=Zeta5;+++[A0A024R817_HUMAN|Unreviewed]SubName: Full=KIAA0415 protein, isoform CRA_d {ECO:0000313|EMBL:EAW87298.1};+++[A4D1Z4_HUMAN|Unreviewed]SubName: Full=KIAA0415 gene product {ECO:0000313|EMBL:EAL23965.1};"]
[9908,"'G3BP2'",1912,1707,1657,1758.66666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003676///nucleic acid binding+++GO:0030159///receptor signaling complex scaffold activity","GO:0034063///stress granule assembly+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0051028///mRNA transport+++GO:0007265///Ras protein signal transduction","G3BP stress granule assembly factor 2","[G3BP2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 2; Short=G3BP-2; AltName: Full=GAP SH3 domain-binding protein 2;+++[A0A024RDB2_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX05747.1};+++[A0A024RDE5_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAX05746.1};+++[D6R9A4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423245}; Flags: Fragment;+++[D6R9X5_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422830}; Flags: Fragment;+++[D6RAC7_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422748}; Flags: Fragment;+++[D6RB17_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424522}; Flags: Fragment;+++[D6RBM9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424060}; Flags: Fragment;+++[D6RBR0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422614}; Flags: Fragment;+++[D6RBW8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423960}; Flags: Fragment;+++[D6RE13_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000425122}; Flags: Fragment;+++[D6REX8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000421621}; Flags: Fragment;+++[D6RGJ4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426311}; Flags: Fragment;+++[H0YAE3_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426843}; Flags: Fragment;"]
[9909,"'DENND4B'",753,762,807,774,{"$nulls":4},"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032483///regulation of Rab protein signal transduction","DENN domain containing 4B","[DEN4B_HUMAN|Reviewed]RecName: Full=DENN domain-containing protein 4B;+++[E9PAK5_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000357635}; Flags: Fragment;+++[H0YEF0_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000435709}; Flags: Fragment;"]
[991,"'CDC20'",28,28,42,32.6666666666667,"04110///Cell cycle+++04111///Cell cycle - yeast+++05203///Viral carcinogenesis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis+++04114///Oocyte meiosis",null,"M00389///APC/C complex",null,"GO:0005680///anaphase-promoting complex+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005819///spindle+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0010997///anaphase-promoting complex binding+++GO:0005515///protein binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:0042826///histone deacetylase binding+++GO:0019899///enzyme binding+++GO:0008022///protein C-terminus binding","GO:0016579///protein deubiquitination+++GO:0050773///regulation of dendrite development+++GO:0051301///cell division+++GO:0090307///mitotic spindle assembly+++GO:0090129///positive regulation of synapse maturation+++GO:0040020///regulation of meiotic nuclear division+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0007399///nervous system development+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0007049///cell cycle+++GO:0031915///positive regulation of synaptic plasticity+++GO:0007094///mitotic spindle assembly checkpoint+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0030154///cell differentiation+++GO:0016567///protein ubiquitination+++GO:0007064///mitotic sister chromatid cohesion+++GO:0008284///positive regulation of cell proliferation","cell division cycle 20","[CDC20_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 20 homolog; AltName: Full=p55CDC;"]
[9910,"'RABGAP1L'",887.03,886,849,874.01,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005929///cilium+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:1902017///regulation of cilium assembly+++GO:0090630///activation of GTPase activity+++GO:0032880///regulation of protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0006897///endocytosis+++GO:0015031///protein transport","RAB GTPase activating protein 1 like","[RBG10_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like, isoform 10;+++[RBG1L_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like;+++[A0A0C4DG54_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000403136}; Flags: Fragment;+++[A0A0U1RQT5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489163}; Flags: Fragment;+++[A0A0U1RQV7_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489188}; Flags: Fragment;+++[A0A0U1RQX4_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489213}; Flags: Fragment;+++[A0A0U1RQY6_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489232};+++[A0A0U1RRM5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489605};+++[E9PNV2_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000432734};+++[E9PS63_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000435911}; Flags: Fragment;+++[F1LJ00_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 18 {ECO:0000313|EMBL:BAH16647.1};+++[F5H8L0_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000375916};+++[Q9Y3L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAB41265.1}; Flags: Fragment;"]
[9911,"'TMCC2'",630,719,570,639.666666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0042982///amyloid precursor protein metabolic process","transmembrane and coiled-coil domain family 2","[TMCC2_HUMAN|Reviewed]RecName: Full=Transmembrane and coiled-coil domains protein 2; AltName: Full=Cerebral protein 11;+++[A0A0C4DFR1_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000331842};+++[A0A1B0GUZ3_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_a {ECO:0000313|EMBL:EAW91545.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000490308};+++[G5E963_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_b {ECO:0000313|EMBL:EAW91546.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000329436};+++[Q8IW47_HUMAN|Unreviewed]SubName: Full=TMCC2 protein {ECO:0000313|EMBL:AAH41019.1}; Flags: Fragment;"]
[9912,"'ARHGAP44'",115,100,104,106.333333333333,"03013///RNA transport+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0042995///cell projection+++GO:0055037///recycling endosome+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine+++GO:0005829///cytosol+++GO:0031256///leading edge membrane+++GO:0030054///cell junction+++GO:0048786///presynaptic active zone+++GO:0005768///endosome","GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding","GO:0043547///positive regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0007165///signal transduction+++GO:0098886///modification of dendritic spine+++GO:0099010///modification of postsynaptic structure+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0006887///exocytosis+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099152///regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 44","[RHG44_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 44; AltName: Full=NPC-A-10; AltName: Full=Rho-type GTPase-activating protein RICH2; AltName: Full=RhoGAP interacting with CIP4 homologs protein 2; Short=RICH-2;+++[A0A087WZS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000482851};+++[A0A2X0U4K4_HUMAN|Unreviewed]SubName: Full=ARHGAP44 {ECO:0000313|EMBL:SPT35710.1}; Flags: Fragment;+++[E7ERK8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000262444};+++[F5H6L3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000437542};+++[J3KRS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000462141};+++[J3QQU7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000463905}; Flags: Fragment;+++[K7EK86_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000465509}; Flags: Fragment;+++[Q69Z00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp564G2272 {ECO:0000313|EMBL:CAH10728.1}; Flags: Fragment;+++[Q8TBK1_HUMAN|Unreviewed]SubName: Full=RICH2 protein {ECO:0000313|EMBL:AAH22452.3}; Flags: Fragment;"]
[9913,"'SUPT7L'",723,795,723,747,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex","GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0046982///protein heterodimerization activity","GO:0043966///histone H3 acetylation+++GO:0051457///maintenance of protein location in nucleus+++GO:1903508///positive regulation of nucleic acid-templated transcription","SPT7 like, STAGA complex gamma subunit","[ST65G_HUMAN|Reviewed]RecName: Full=STAGA complex 65 subunit gamma; AltName: Full=Adenocarcinoma antigen ART1; AltName: Full=SPTF-associated factor 65 gamma; Short=STAF65gamma; AltName: Full=Suppressor of Ty 7-like;"]
[9914,"'ATP2C2'",1,6,8,5,null,"H00844///Familial benign chronic pemphigus",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005388///calcium-transporting ATPase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0015410///manganese-transporting ATPase activity+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0090280///positive regulation of calcium ion import+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0006874///cellular calcium ion homeostasis+++GO:0070588///calcium ion transmembrane transport+++GO:0006816///calcium ion transport+++GO:0006811///ion transport+++GO:1902600///proton transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0061180///mammary gland epithelium development","ATPase secretory pathway Ca2+ transporting 2","[AT2C2_HUMAN|Reviewed]RecName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000305}; Short=ATPase 2C2; EC=3.6.3.8; AltName: Full=Secretory pathway Ca(2+)-ATPase 2;+++[A0A0A0MSP0_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[B3KR57_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[H3BS90_HUMAN|Unreviewed]SubName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000313|Ensembl:ENSP00000456595}; Flags: Fragment;"]
[9915,"'ARNT2'",3074,3380,2959,3137.66666666667,"05200///Pathways in cancer+++05211///Renal cell carcinoma+++05202///Transcriptional misregulation in cancer","H01797///Webb-Dattani syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0032355///response to estradiol+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006805///xenobiotic metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II","aryl hydrocarbon receptor nuclear translocator 2","[ARNT2_HUMAN|Reviewed]RecName: Full=Aryl hydrocarbon receptor nuclear translocator 2; Short=ARNT protein 2; AltName: Full=Class E basic helix-loop-helix protein 1; Short=bHLHe1;+++[A0A087WVE9_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000479393};+++[H0YKW1_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000452961}; Flags: Fragment;+++[Q7Z3A3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686M216 {ECO:0000313|EMBL:CAD97972.1};+++[Q86TN1_HUMAN|Unreviewed]SubName: Full=ARNT2 protein {ECO:0000313|EMBL:AAH51335.1};+++[X5D7T2_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56635.1};+++[X5D8U0_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform G {ECO:0000313|EMBL:AHW56413.1}; Flags: Fragment;+++[X5D9H9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform B {ECO:0000313|EMBL:AHW56648.1};+++[X5DP31_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform E {ECO:0000313|EMBL:AHW56626.1};+++[X5DP40_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56636.1};+++[X5DP87_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform F {ECO:0000313|EMBL:AHW56696.1};+++[X5DQN9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform D {ECO:0000313|EMBL:AHW56412.1}; Flags: Fragment;+++[X5DRE4_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform H {ECO:0000313|EMBL:AHW56647.1};"]
[9917,"'FAM20B'",623,528.93,544,565.31,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","FAM20B, glycosaminoglycan xylosylkinase","[XYLK_HUMAN|Reviewed]RecName: Full=Glycosaminoglycan xylosylkinase; EC=2.7.1.- {ECO:0000269|PubMed:19473117}; AltName: Full=Xylose kinase;+++[A0A024R918_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 20, member B, isoform CRA_a {ECO:0000313|EMBL:EAW91036.1};+++[X6RH03_HUMAN|Unreviewed]SubName: Full=Glycosaminoglycan xylosylkinase {ECO:0000313|Ensembl:ENSP00000404005}; Flags: Fragment;"]
[9918,"'NCAPD2'",739,720,667,708.666666666667,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0000799///nuclear condensin complex+++GO:0000228///nuclear chromosome+++GO:0000793///condensed chromosome+++GO:0016020///membrane+++GO:0000797///condensin core heterodimer+++GO:0005829///cytosol+++GO:0000779///condensed chromosome, centromeric region+++GO:0005737///cytoplasm","GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding","GO:0051304///chromosome separation+++GO:0010032///meiotic chromosome condensation+++GO:0007049///cell cycle+++GO:0030261///chromosome condensation+++GO:0007076///mitotic chromosome condensation+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","non-SMC condensin I complex subunit D2","[CND1_HUMAN|Reviewed]RecName: Full=Condensin complex subunit 1; AltName: Full=Chromosome condensation-related SMC-associated protein 1; AltName: Full=Chromosome-associated protein D2; Short=hCAP-D2; AltName: Full=Non-SMC condensin I complex subunit D2; AltName: Full=XCAP-D2 homolog;+++[A0PJ76_HUMAN|Unreviewed]SubName: Full=NCAPD2 protein {ECO:0000313|EMBL:AAH16913.1}; Flags: Fragment;+++[B3KMS0_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[B3KY03_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[E7EN77_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000371895}; Flags: Fragment;+++[F5GZK7_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000444377}; Flags: Fragment;+++[F5H431_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000438495};"]
[9919,"'SEC16A'",3767,4367,3944,4026,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0031090///organelle membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding","GO:0007030///Golgi organization+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0043000///Golgi to plasma membrane CFTR protein transport+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0007029///endoplasmic reticulum organization+++GO:0050821///protein stabilization+++GO:0034976///response to endoplasmic reticulum stress+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0021762///substantia nigra development+++GO:0072659///protein localization to plasma membrane+++GO:0016192///vesicle-mediated transport+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0006888///ER to Golgi vesicle-mediated transport","SEC16 homolog A, endoplasmic reticulum export factor","[SC16A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec16A; AltName: Full=SEC16 homolog A;+++[A0A0C4DH09_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000277537}; Flags: Fragment;+++[A0PJ75_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH16873.1}; Flags: Fragment;+++[A4QN18_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[A4QN19_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[F1T0I1_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[G1UI25_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|EMBL:BAK64148.1}; Flags: Fragment;+++[J3KNL6_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[Q8N9G1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000317437}; SubName: Full=cDNA FLJ37437 fis, clone BRAWH2003025 {ECO:0000313|EMBL:BAC04415.1};+++[Q9BV84_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH01404.2}; Flags: Fragment;+++[X6RGP5_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;"]
[9920,"'KBTBD11'",823,711,685,739.666666666667,{"$nulls":4},"GO:0031463///Cul3-RING ubiquitin ligase complex",null,"GO:0016567///protein ubiquitination","kelch repeat and BTB domain containing 11","[KBTBB_HUMAN|Reviewed]RecName: Full=Kelch repeat and BTB domain-containing protein 11; AltName: Full=Chronic myelogenous leukemia-associated protein; AltName: Full=Kelch domain-containing protein 7B;"]
[9921,"'RNF10'",2284,2429,2226,2313,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding","GO:0051865///protein autoubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031643///positive regulation of myelination+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated","ring finger protein 10","[RNF10_HUMAN|Reviewed]RecName: Full=RING finger protein 10;+++[A0A024RBP0_HUMAN|Unreviewed]SubName: Full=Ring finger protein 10, isoform CRA_a {ECO:0000313|EMBL:EAW98203.1};+++[A0A0G2JKT9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000438638}; Flags: Fragment;+++[F5H3A4_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439221}; Flags: Fragment;+++[F5H510_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000444770}; Flags: Fragment;+++[F5H5P6_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443235}; Flags: Fragment;+++[F5H5Z1_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443000};+++[H0YF69_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000437392}; Flags: Fragment;+++[H0YFN9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439510}; Flags: Fragment;+++[H0YFQ9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439859}; Flags: Fragment;+++[H0YG28_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000441487}; Flags: Fragment;+++[H0YGL7_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443790}; Flags: Fragment;+++[H0YGX5_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000445160}; Flags: Fragment;"]
[9922,"'IQSEC1'",3861,4706,4048,4205,"04144///Endocytosis","H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032012///regulation of ARF protein signal transduction+++GO:0051549///positive regulation of keratinocyte migration+++GO:0043547///positive regulation of GTPase activity+++GO:1903393///positive regulation of adherens junction organization+++GO:0030036///actin cytoskeleton organization","IQ motif and Sec7 domain 1","[IQEC1_HUMAN|Reviewed]RecName: Full=IQ motif and SEC7 domain-containing protein 1; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 100; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 2; AltName: Full=Brefeldin-resistant Arf-GEF 2 protein {ECO:0000303|PubMed:16461286}; Short=BRAG2 {ECO:0000303|PubMed:24058294};+++[A0A087WWK8_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000480301};+++[A0A0C4DGT3_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000478001};+++[A0A2R8Y695_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000495163}; Flags: Fragment;+++[A0A2R8Y7T6_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496366};+++[B4DGC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60491, highly similar to IQ motif and Sec7 domain-containing protein 1 {ECO:0000313|EMBL:BAG57736.1};+++[L0R4Y9_HUMAN|Unreviewed]SubName: Full=Alternative protein IQSEC1 {ECO:0000313|EMBL:CCO13748.1};"]
[9923,"'ZBTB40'",481,524,520,508.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0030282///bone mineralization+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 40","[ZBT40_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 40;+++[B1AKC8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000383098}; Flags: Fragment;+++[B2RBP0_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 40, isoform CRA_a {ECO:0000313|EMBL:EAW95011.1}; SubName: Full=cDNA, FLJ95610, Homo sapiens KIAA0478 gene product (KIAA0478), mRNA {ECO:0000313|EMBL:BAG37287.1};+++[B3KR52_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33700 fis, clone BRAWH2005074, highly similar to Zinc finger and BTB domain-containing protein 40 {ECO:0000313|EMBL:BAG52264.1}; Flags: Fragment;+++[F8WAI8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000363782};+++[Q1RMZ5_HUMAN|Unreviewed]SubName: Full=ZBTB40 protein {ECO:0000313|EMBL:AAI14608.1};"]
[9924,"'PAN2'",426,619,466,503.666666666667,"03018///RNA degradation",null,"M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00010///Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate+++M00740///Methylaspartate cycle+++M00012///Glyoxylate cycle","R00351///acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing) Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate","GO:0000932///P-body+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0031251///PAN complex+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0004108///citrate (Si)-synthase activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0000175///3'-5'-exoribonuclease activity","GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0006397///mRNA processing+++GO:0005975///carbohydrate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening","poly(A) specific ribonuclease subunit PAN2","[PAN2_HUMAN|Reviewed]RecName: Full=PAN2-PAN3 deadenylation complex catalytic subunit PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}; EC=3.1.13.4 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 52 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=PAB1P-dependent poly(A)-specific ribonuclease {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Poly(A)-nuclease deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182}; Short=PAN deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182};"]
[9925,"'ZBTB5'",477,460,439,458.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus","zinc finger and BTB domain containing 5","[ZBTB5_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 5;+++[Q5T942_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 5 {ECO:0000313|EMBL:EAW58282.1}; SubName: Full=cDNA FLJ77230, highly similar to Homo sapiens zinc finger and BTB domain containing 5 (ZBTB5), mRNA {ECO:0000313|EMBL:BAF85093.1};"]
[9926,"'LPGAT1'",366,429,373.01,389.336666666667,"00564///Glycerophospholipid metabolism",null,null,"R09036///acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0003674///molecular_function","GO:0006629///lipid metabolic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","lysophosphatidylglycerol acyltransferase 1","[LGAT1_HUMAN|Reviewed]RecName: Full=Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; EC=2.3.1.-;"]
[9927,"'MFN2'",1986,2061,1955,2000.66666666667,"04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway+++04214///Apoptosis - fly","H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0031306///intrinsic component of mitochondrial outer membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton","GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0001825///blastocyst formation+++GO:0007050///cell cycle arrest+++GO:0006986///response to unfolded protein+++GO:0007596///blood coagulation+++GO:0051646///mitochondrion localization+++GO:0006914///autophagy+++GO:0048593///camera-type eye morphogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:0016236///macroautophagy+++GO:0006626///protein targeting to mitochondrion+++GO:0008053///mitochondrial fusion+++GO:0006915///apoptotic process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0034497///protein localization to phagophore assembly site+++GO:0007006///mitochondrial membrane organization","mitofusin 2","[MFN2_HUMAN|Reviewed]RecName: Full=Mitofusin-2; EC=3.6.5.-; AltName: Full=Transmembrane GTPase MFN2;+++[Q5JXC5_HUMAN|Unreviewed]SubName: Full=Mitofusin-2 {ECO:0000313|Ensembl:ENSP00000412023}; Flags: Fragment;"]
[9928,"'KIF14'",4,3,1,2.66666666666667,null,"H01513///Retinoblastoma+++H00261///Meckel syndrome (MKS)",null,null,"GO:0005874///microtubule+++GO:0005819///spindle+++GO:0030496///midbody+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0051233///spindle midzone+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0015631///tubulin binding+++GO:0030165///PDZ domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed","GO:0021695///cerebellar cortex development+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0032467///positive regulation of cytokinesis+++GO:0051301///cell division+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0032147///activation of protein kinase activity+++GO:0021846///cell proliferation in forebrain+++GO:0033624///negative regulation of integrin activation+++GO:0021693///cerebellar Purkinje cell layer structural organization+++GO:0021772///olfactory bulb development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0030155///regulation of cell adhesion+++GO:0007080///mitotic metaphase plate congression+++GO:0021766///hippocampus development+++GO:0032487///regulation of Rap protein signal transduction+++GO:0043523///regulation of neuron apoptotic process+++GO:0007019///microtubule depolymerization+++GO:0045184///establishment of protein localization+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0021685///cerebellar granular layer structural organization+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0008284///positive regulation of cell proliferation+++GO:0031641///regulation of myelination+++GO:0007018///microtubule-based movement+++GO:0030334///regulation of cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0021987///cerebral cortex development+++GO:1903429///regulation of cell maturation+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process","kinesin family member 14","[KIF14_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF14 {ECO:0000305};"]
[9929,"'JOSD1'",940,905,808,884.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","Josephin domain containing 1","[JOS1_HUMAN|Reviewed]RecName: Full=Josephin-1; EC=3.4.19.12; AltName: Full=Josephin domain-containing protein 1;+++[A0A024R1P5_HUMAN|Unreviewed]SubName: Full=Josephin domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW60260.1};+++[B0QY55_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000393131}; Flags: Fragment;+++[B0QY56_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000410010}; Flags: Fragment;+++[B0QY57_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000415189}; Flags: Fragment;+++[B0QY58_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000405182}; Flags: Fragment;+++[H0YGT9_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000444798}; Flags: Fragment;"]
[993,"'CDC25A'",23,11,14,16,"05206///MicroRNAs in cancer+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04218///Cellular senescence",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0051087///chaperone binding","GO:0007049///cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016579///protein deubiquitination+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0009314///response to radiation+++GO:0034644///cellular response to UV","cell division cycle 25A","[MPIP1_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 1; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25A;+++[A0A024R2R6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_b {ECO:0000313|EMBL:EAW64852.1};+++[A0A024R2S4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_a {ECO:0000313|EMBL:EAW64851.1};+++[C9JFR5_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000416483}; Flags: Fragment;+++[C9JH94_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000404285}; Flags: Fragment;+++[D8KXX0_HUMAN|Unreviewed]SubName: Full=CDC25A2-CAG isoform {ECO:0000313|EMBL:ACI43572.1};+++[K7N7S0_HUMAN|Unreviewed]SubName: Full=CDC25 isoform A1-CAG {ECO:0000313|EMBL:ACZ05628.1};"]
[9931,"'HELZ'",882,1046,899,942.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043186///P granule+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding","GO:0035194///posttranscriptional gene silencing by RNA","helicase with zinc finger","[HELZ_HUMAN|Reviewed]RecName: Full=Probable helicase with zinc finger domain; EC=3.6.4.-; AltName: Full=Down-regulated in human cancers protein;+++[A0A024R8K8_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger, isoform CRA_a {ECO:0000313|EMBL:EAW89024.1};+++[A0A075B6R3_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000411144};+++[A0A2P0H7U5_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger {ECO:0000313|EMBL:AAI30583.1};+++[B7ZLW2_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAI44084.1};+++[C1KEM4_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49579.1}; Flags: Fragment;+++[C1KEM5_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49580.1}; Flags: Fragment;+++[J3KS59_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462320}; Flags: Fragment;+++[J3KT20_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462763}; Flags: Fragment;+++[J3QRR8_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464354}; Flags: Fragment;+++[J3QS41_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464512};+++[Q6PGP6_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAH56895.1}; Flags: Fragment;"]
[9933,"'PUM3'",389,413,375,392.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0010835///regulation of protein ADP-ribosylation","pumilio RNA binding family member 3","[PUM3_HUMAN|Reviewed]RecName: Full=Pumilio homolog 3 {ECO:0000305}; AltName: Full=HBV X-transactivated gene 5 protein; AltName: Full=HBV XAg-transactivated protein 5; AltName: Full=Minor histocompatibility antigen HA-8; Short=HLA-HA8;+++[Q9NYH5_HUMAN|Unreviewed]SubName: Full=KIAA0020 protein {ECO:0000313|EMBL:AAF69838.1}; Flags: Fragment;+++[S4R3K8_HUMAN|Unreviewed]SubName: Full=Pumilio homolog 3 {ECO:0000313|Ensembl:ENSP00000474467}; Flags: Fragment;"]
[9935,"'MAFB'",42,16,33,30.3333333333333,"04928///Parathyroid hormone synthesis, secretion and action","H01865///Multicentric carpotarsal osteolysis syndrome",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0007379///segment specification+++GO:0007585///respiratory gaseous exchange+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042472///inner ear morphogenesis+++GO:0021571///rhombomere 5 development+++GO:0021572///rhombomere 6 development+++GO:0007423///sensory organ development+++GO:0033077///T cell differentiation in thymus+++GO:0035284///brain segmentation+++GO:0021599///abducens nerve formation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0048538///thymus development","MAF bZIP transcription factor B","[MAFB_HUMAN|Reviewed]RecName: Full=Transcription factor MafB; Short=Maf-B; AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog B;+++[L8ECC4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAFB {ECO:0000313|EMBL:CCQ43322.1};"]
[9936,"'CD302'",138.59,149,146.28,144.623333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005902///microvillus+++GO:0030175///filopodium+++GO:0005938///cell cortex+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0006909///phagocytosis","CD302 molecule","[CD302_HUMAN|Reviewed]RecName: Full=CD302 antigen; AltName: Full=C-type lectin BIMLEC; AltName: Full=C-type lectin domain family 13 member A; AltName: Full=DEC205-associated C-type lectin 1; AltName: Full=Type I transmembrane C-type lectin receptor DCL-1; AltName: CD_antigen=CD302; Flags: Precursor;+++[A0A087WT00_HUMAN|Unreviewed]SubName: Full=CD302 antigen {ECO:0000313|Ensembl:ENSP00000451446};"]
[9937,"'DCLRE1A'",131,122,150,134.333333333333,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0003684///damaged DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0051301///cell division+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0007049///cell cycle","DNA cross-link repair 1A","[DCR1A_HUMAN|Reviewed]RecName: Full=DNA cross-link repair 1A protein; AltName: Full=SNM1 homolog A; Short=hSNM1; Short=hSNM1A;"]
[9938,"'ARHGAP25'",5,8,6,6.33333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0001891///phagocytic cup","GO:0005096///GTPase activator activity","GO:0006911///phagocytosis, engulfment+++GO:0007165///signal transduction+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007015///actin filament organization+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 25","[RHG25_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 25; AltName: Full=Rho-type GTPase-activating protein 25;+++[A0A2X0TVS2_HUMAN|Unreviewed]SubName: Full=ARHGAP25 {ECO:0000313|EMBL:SPT35696.1}; Flags: Fragment;+++[B7Z8K7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417283}; SubName: Full=cDNA FLJ59112, highly similar to Rho-GTPase-activating protein 25 {ECO:0000313|EMBL:BAH13993.1};+++[C9JB56_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417467};+++[F8WAV9_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417425};+++[F8WDF6_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000420427};+++[H7C4P1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417818}; Flags: Fragment;+++[V9HWC8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 308 {ECO:0000313|EMBL:ACJ13710.1}; SubName: Full=Rho GTPase activating protein 25, isoform CRA_b {ECO:0000313|EMBL:EAW99867.1};"]
[9939,"'RBM8A'",1457.01,1394,1365,1405.33666666667,"03015///mRNA surveillance pathway+++03040///Spliceosome+++03013///RNA transport","H01847///Thrombocytopenia-absent radius syndrome","M00430///Exon junction complex (EJC)",null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0071013///catalytic step 2 spliceosome+++GO:0035145///exon-exon junction complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding","GO:0031124///mRNA 3'-end processing+++GO:0006417///regulation of translation+++GO:0006396///RNA processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0051028///mRNA transport+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006406///mRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 8A","[RBM8A_HUMAN|Reviewed]RecName: Full=RNA-binding protein 8A; AltName: Full=Binder of OVCA1-1; Short=BOV-1; AltName: Full=RNA-binding motif protein 8A; AltName: Full=RNA-binding protein Y14; AltName: Full=Ribonucleoprotein RBM8A;+++[A0A023T787_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239};+++[A0A060D9J6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 8A {ECO:0000313|EMBL:AIB06359.1}; Flags: Fragment;+++[A0A0J9YW13_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239}; Flags: Fragment;+++[L8E9A7_HUMAN|Unreviewed]SubName: Full=Alternative protein RBM8A {ECO:0000313|EMBL:CCQ43301.1};"]
[994,"'CDC25B'",311,341,350,334,"04110///Cell cycle+++05206///MicroRNAs in cancer+++04010///MAPK signaling pathway+++04914///Progesterone-mediated oocyte maturation",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0001556///oocyte maturation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0007144///female meiosis I+++GO:0007049///cell cycle+++GO:0000278///mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0006468///protein phosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0051301///cell division+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0032467///positive regulation of cytokinesis","cell division cycle 25B","[MPIP2_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 2; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25B;+++[B3KS38_HUMAN|Unreviewed]SubName: Full=HCG39252, isoform CRA_g {ECO:0000313|EMBL:EAX10500.1}; SubName: Full=Isoform CDC25B6 {ECO:0000313|EMBL:CBX26628.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26628.1}; SubName: Full=cDNA FLJ35394 fis, clone SKNSH2002768, highly similar to M-PHASE INDUCER PHOSPHATASE 2 {ECO:0000313|EMBL:BAG52600.1};+++[B4DIG0_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000339125}; SubName: Full=cDNA FLJ53333, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG58472.1};+++[B4DQZ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55479, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61105.1};+++[B4DRC3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56140, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61235.1};+++[E1YMX4_HUMAN|Unreviewed]SubName: Full=Isoform CDC25B7 {ECO:0000313|EMBL:CBX26629.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26629.1};+++[G8JLH2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000368918};+++[L8E819_HUMAN|Unreviewed]SubName: Full=Alternative protein CDC25B {ECO:0000313|EMBL:CCQ43259.1};+++[O43550_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94625.1}; Flags: Fragment;+++[Q6MZW8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G14213 {ECO:0000313|EMBL:CAE45909.2}; Flags: Fragment;+++[Q7LDQ7_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94623.1}; Flags: Fragment;"]
[9940,"'DLEC1'",13,14,13,13.3333333333333,"00592///alpha-Linolenic acid metabolism+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++04146///Peroxisome+++00280///Valine, leucine and isoleucine degradation+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03320///PPAR signaling pathway+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism",null,"M00087///beta-Oxidation+++M00113///Jasmonic acid biosynthesis","R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R07953///(4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapenta-6,9,12,15,18-enoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R07891///OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R07937///(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexa-6,9,12,15,18,21-enoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA+++R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R07899///(+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA+++R07895///OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA","GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0005925///focal adhesion+++GO:0005901///caveola","GO:0003674///molecular_function+++GO:0005096///GTPase activator activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding","GO:0030900///forebrain development+++GO:0008285///negative regulation of cell proliferation+++GO:0021575///hindbrain morphogenesis+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:0008360///regulation of cell shape+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007165///signal transduction+++GO:0003007///heart morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0006915///apoptotic process+++GO:0051497///negative regulation of stress fiber assembly+++GO:0048041///focal adhesion assembly+++GO:0001843///neural tube closure+++GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity","DLEC1, cilia and flagella associated protein","[DLEC1_HUMAN|Reviewed]RecName: Full=Deleted in lung and esophageal cancer protein 1; AltName: Full=Deleted in lung cancer protein 1; Short=DLC-1;+++[A1L305_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29825.1};+++[A2VDF1_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29826.1}; Flags: Fragment;+++[B1B5Y4_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|EMBL:BAG11659.1}; Flags: Fragment;+++[B7ZW06_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 {ECO:0000313|EMBL:AAI71799.1};+++[Q32W76_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 3 {ECO:0000313|EMBL:AAX18635.1}; SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|Ensembl:ENSP00000404261}; Flags: Fragment;+++[Q32W77_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript varient 2 {ECO:0000313|EMBL:AAX18634.1}; Flags: Fragment;+++[Q32W78_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 1 {ECO:0000313|EMBL:AAX18633.1}; Flags: Fragment;"]
[9941,"'EXOG'",111,112,109,110.666666666667,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004529///exodeoxyribonuclease activity+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0008409///5'-3' exonuclease activity","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006309///apoptotic DNA fragmentation+++GO:0008150///biological_process","exo/endonuclease G","[EXOG_HUMAN|Reviewed]RecName: Full=Nuclease EXOG, mitochondrial; EC=3.1.30.-; AltName: Full=Endonuclease G-like 1; Short=Endo G-like 1; Flags: Precursor;+++[A0A024R2T8_HUMAN|Unreviewed]SubName: Full=Endonuclease G-like 1, isoform CRA_b {ECO:0000313|EMBL:EAW64539.1};+++[F2Z2D3_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000400239};+++[F8WC11_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000412756};+++[F8WE28_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000394977};+++[F8WE38_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000402164};+++[F8WEP0_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000413176};+++[H0Y8P1_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000421649}; Flags: Fragment;+++[H7C0W6_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000397124}; Flags: Fragment;+++[H7C451_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000415568}; Flags: Fragment;"]
[9942,"'XYLB'",257,457.44,348.96,354.466666666667,"00040///Pentose and glucuronate interconversions+++01100///Metabolic pathways","H00632///Heterotaxy","M00014///Glucuronate pathway (uronate pathway)","R01639///ATP:D-xylulose 5-phosphotransferase   ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0004856///xylulokinase activity","GO:0005975///carbohydrate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0005997///xylulose metabolic process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0016310///phosphorylation+++GO:0005998///xylulose catabolic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0042732///D-xylose metabolic process","xylulokinase","[XYLB_HUMAN|Reviewed]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;+++[C9J0N9_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000412282};+++[F8WBF6_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000398845};+++[Q6PIS3_HUMAN|Unreviewed]SubName: Full=XYLB protein {ECO:0000313|EMBL:AAH30231.1}; Flags: Fragment;"]
[9943,"'OXSR1'",797,720,702,739.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0042802///identical protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity","GO:0072143///mesangial cell development+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0002062///chondrocyte differentiation+++GO:1990869///cellular response to chemokine+++GO:0072207///metanephric epithelium development+++GO:0023014///signal transduction by protein phosphorylation+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:0001657///ureteric bud development+++GO:0072169///specification of posterior mesonephric tubule identity+++GO:0072168///specification of anterior mesonephric tubule identity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0072111///cell proliferation involved in kidney development+++GO:0072166///posterior mesonephric tubule development+++GO:0006979///response to oxidative stress+++GO:0001655///urogenital system development+++GO:0032147///activation of protein kinase activity+++GO:0048863///stem cell differentiation+++GO:0048793///pronephros development+++GO:0072234///metanephric nephron tubule development+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0042733///embryonic digit morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0023016///signal transduction by trans-phosphorylation+++GO:0001823///mesonephros development+++GO:0071476///cellular hypotonic response+++GO:2000543///positive regulation of gastrulation+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0038146///chemokine (C-X-C motif) ligand 12 signaling pathway+++GO:0071300///cellular response to retinoic acid+++GO:0060021///roof of mouth development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0072180///mesonephric duct morphogenesis+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:0072190///ureter urothelium development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0042474///middle ear morphogenesis+++GO:0072184///renal vesicle progenitor cell differentiation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0016310///phosphorylation+++GO:0072259///metanephric interstitial fibroblast development+++GO:0007231///osmosensory signaling pathway+++GO:0030154///cell differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072268///pattern specification involved in metanephros development+++GO:0042476///odontogenesis+++GO:0072183///negative regulation of nephron tubule epithelial cell differentiation+++GO:0008406///gonad development+++GO:0072075///metanephric mesenchyme development+++GO:0072498///embryonic skeletal joint development+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0072208///metanephric smooth muscle tissue development+++GO:0043066///negative regulation of apoptotic process+++GO:0030501///positive regulation of bone mineralization+++GO:0001656///metanephros development+++GO:0035556///intracellular signal transduction+++GO:0090094///metanephric cap mesenchymal cell proliferation involved in metanephros development+++GO:0046777///protein autophosphorylation+++GO:0048389///intermediate mesoderm development","oxidative stress responsive 1","[OXSR1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase OSR1; EC=2.7.11.1; AltName: Full=Oxidative stress-responsive 1 protein;+++[A0A024R2M7_HUMAN|Unreviewed]SubName: Full=Oxidative-stress responsive 1, isoform CRA_a {ECO:0000313|EMBL:EAW64523.1};+++[C9JIG9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000415851};+++[F8WBK9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000398356};+++[L8ECC0_HUMAN|Unreviewed]SubName: Full=Alternative protein OXSR1 {ECO:0000313|EMBL:CCQ43302.1};"]
[9945,"'GFPT2'",96,117,97,103.333333333333,"01130///Biosynthesis of antibiotics+++00250///Alanine, aspartate and glutamate metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++04931///Insulin resistance+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome",null,"R00768///L-glutamine:D-fructose-6-phosphate isomerase (deaminating); L-glutamine:D-fructose-6-phosphate   L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate","GO:0005829///cytosol","GO:0008483///transaminase activity+++GO:0005515///protein binding+++GO:0097367///carbohydrate derivative binding+++GO:0016740///transferase activity+++GO:0004360///glutamine-fructose-6-phosphate transaminase (isomerizing) activity","GO:0006541///glutamine metabolic process+++GO:0006112///energy reserve metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:1901135///carbohydrate derivative metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:1901137///carbohydrate derivative biosynthetic process+++GO:0006487///protein N-linked glycosylation","glutamine-fructose-6-phosphate transaminase 2","[GFPT2_HUMAN|Reviewed]RecName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2; EC=2.6.1.16 {ECO:0000250|UniProtKB:P82808}; AltName: Full=D-fructose-6-phosphate amidotransferase 2; AltName: Full=Glutamine:fructose-6-phosphate amidotransferase 2; Short=GFAT 2; Short=GFAT2; AltName: Full=Hexosephosphate aminotransferase 2;+++[A0A0S2Z4W6_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 2 {ECO:0000313|EMBL:ALQ33953.1}; Flags: Fragment;+++[A0A0S2Z4X9_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 1 {ECO:0000313|EMBL:ALQ33952.1}; SubName: Full=Glutamine-fructose-6-phosphate transaminase 2, isoform CRA_b {ECO:0000313|EMBL:EAW53756.1}; Flags: Fragment;+++[B3KMR8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12445 fis, clone NT2RM1000256, highly similar to Glucosamine--fructose-6-phosphateaminotransferase (isomerizing) 2 {ECO:0000313|EMBL:BAG51080.1};+++[D6RAC1_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000422771}; Flags: Fragment;+++[E5RJP4_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000431125}; Flags: Fragment;"]
[9946,"'CRYZL1'",116,106,113,111.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H02132///Microcephaly syndrome",null,null,"GO:0005829///cytosol","GO:0050661///NADP binding+++GO:0016491///oxidoreductase activity+++GO:0003960///NADPH:quinone reductase activity","GO:1901661///quinone metabolic process+++GO:0055114///oxidation-reduction process","crystallin zeta like 1","[QORL1_HUMAN|Reviewed]RecName: Full=Quinone oxidoreductase-like protein 1; EC=1.-.-.-; AltName: Full=Protein 4P11; AltName: Full=Quinone oxidoreductase homolog 1; Short=QOH-1; AltName: Full=Zeta-crystallin homolog;+++[A0A0C4DG14_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000389209};+++[A6NHJ8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000355075};+++[A6NMA8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000290244};+++[A6NND8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000370951};+++[A8MZ10_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000382371};+++[C9JAL0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000405510}; Flags: Fragment;+++[C9JNR9_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000408385}; Flags: Fragment;+++[C9JQD0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000402844}; Flags: Fragment;+++[C9JZK8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399730};+++[C9K0F7_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000387660}; Flags: Fragment;+++[F8WF64_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399937};+++[H7C0X3_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000397318}; Flags: Fragment;+++[H7C2K1_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000406423}; Flags: Fragment;+++[H7C338_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000409387}; Flags: Fragment;+++[H7C3I5_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000412087}; Flags: Fragment;+++[H7C3S0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000413513}; Flags: Fragment;+++[Q8TBV9_HUMAN|Unreviewed]SubName: Full=CRYZL1 protein {ECO:0000313|EMBL:AAH22827.1}; Flags: Fragment;"]
[9948,"'WDR1'",9261,7474,7554,8096.33333333333,null,"H00948///Renal hypouricemia (RHUC)",null,null,"GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection+++GO:0042643///actomyosin, actin portion+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0002102///podosome+++GO:0043209///myelin sheath+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction","GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0007605///sensory perception of sound+++GO:0045214///sarcomere organization+++GO:0030042///actin filament depolymerization+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0040011///locomotion+++GO:0002576///platelet degranulation+++GO:0030834///regulation of actin filament depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0030220///platelet formation+++GO:0002446///neutrophil mediated immunity+++GO:0008360///regulation of cell shape+++GO:0043297///apical junction assembly+++GO:0042247///establishment of planar polarity of follicular epithelium+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0030043///actin filament fragmentation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:1990266///neutrophil migration+++GO:0030865///cortical cytoskeleton organization","WD repeat domain 1","[WDR1_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 1; AltName: Full=Actin-interacting protein 1; Short=AIP1; AltName: Full=NORI-1;+++[D6RD66_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000425481}; Flags: Fragment;+++[L8E9Y5_HUMAN|Unreviewed]SubName: Full=Alternative protein WDR1 {ECO:0000313|EMBL:CCQ43551.1};+++[Q53GN4_HUMAN|Unreviewed]SubName: Full=WD repeat domain 1, isoform CRA_a {ECO:0000313|EMBL:EAW92686.1}; SubName: Full=WD repeat-containing protein 1 isoform 1 variant {ECO:0000313|EMBL:BAD96617.1}; Flags: Fragment;+++[V9HWG7_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 52 {ECO:0000313|EMBL:ACJ13729.1};"]
[9949,"'AMMECR1'",191,182,179,184,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus","GO:0005515///protein binding","GO:0008150///biological_process","Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1","[AMMR1_HUMAN|Reviewed]RecName: Full=AMME syndrome candidate gene 1 protein;+++[A0A0S2Z4V0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33954.1}; Flags: Fragment;+++[A0A0S2Z4X0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33955.1}; SubName: Full=Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region, gene 1 {ECO:0000313|EMBL:EAX02663.1}; Flags: Fragment;"]
[995,"'CDC25C'",6,2,1,3,"05206///MicroRNAs in cancer+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation",null,"M00693///Cell cycle - G2/M transition+++M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0016787///hydrolase activity+++GO:0004725///protein tyrosine phosphatase activity","GO:0000086///G2/M transition of mitotic cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007283///spermatogenesis+++GO:0051301///cell division+++GO:0006470///protein dephosphorylation+++GO:0008283///cell proliferation+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division","cell division cycle 25C","[MPIP3_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 3; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25C;+++[B4DX61_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56262, highly similar to M-phase inducer phosphatase 3 {ECO:0000313|EMBL:BAG63273.1};+++[D6RD20_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427105}; Flags: Fragment;+++[D6RJC2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427251}; Flags: Fragment;+++[H0Y999_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000423525}; Flags: Fragment;+++[Q9H2F0_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25C splice variant 3 {ECO:0000313|EMBL:AAG41886.1}; Flags: Fragment;"]
[9950,"'GOLGA5'",799,836,716,783.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031985///Golgi cisterna+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005801///cis-Golgi network+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0017137///Rab GTPase binding","GO:0007030///Golgi organization+++GO:0048193///Golgi vesicle transport+++GO:0000301///retrograde transport, vesicle recycling within Golgi","golgin A5","[GOGA5_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 5; AltName: Full=Cell proliferation-inducing gene 31 protein; AltName: Full=Golgin-84; AltName: Full=Protein Ret-II; AltName: Full=RET-fused gene 5 protein;"]
[9951,"'HS3ST4'",12,7,4,7.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity","GO:0030201///heparan sulfate proteoglycan metabolic process","heparan sulfate-glucosamine 3-sulfotransferase 4","[HS3S4_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 4; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4; Short=3-OST-4; Short=Heparan sulfate 3-O-sulfotransferase 4; Short=h3-OST-4;+++[A5H458_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155}; Flags: Fragment;"]
[9953,"'HS3ST3B1'",99.42,111.55,141.63,117.533333333333,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0016740///transferase activity","GO:0006477///protein sulfation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification","heparan sulfate-glucosamine 3-sulfotransferase 3B1","[HS3SB_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; Short=3-OST-3B; Short=Heparan sulfate 3-O-sulfotransferase 3B1; Short=h3-OST-3B;"]
[9955,"'HS3ST3A1'",159.58,119.45,180.37,153.133333333333,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 3A1","[HS3SA_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Short=3-OST-3A; Short=Heparan sulfate 3-O-sulfotransferase 3A1; Short=h3-OST-3A;+++[J3KSX5_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9956,"'HS3ST2'",0,0,1,0.333333333333333,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0033871///[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity","GO:0007623///circadian rhythm+++GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 2","[HS3S2_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 2; EC=2.8.2.29; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2; Short=3-OST-2; Short=Heparan sulfate 3-O-sulfotransferase 2; Short=h3-OST-2;+++[H3BMR2_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9957,"'HS3ST1'",25,24,25,24.6666666666667,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0005796///Golgi lumen+++GO:0005794///Golgi apparatus","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity+++GO:0008146///sulfotransferase activity","GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 1","[HS3S1_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Short=3-OST-1; Short=Heparan sulfate 3-O-sulfotransferase 1; Short=h3-OST-1; Flags: Precursor;+++[A0A024R9R4_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[E9PDE3_HUMAN|Unreviewed]SubName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1 {ECO:0000313|Ensembl:ENSP00000425673}; Flags: Fragment;+++[Q05CH3_HUMAN|Unreviewed]SubName: Full=HS3ST1 protein {ECO:0000313|EMBL:AAH25735.1}; Flags: Fragment;"]
[9958,"'USP15'",346,263,296,301.666666666667,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity+++GO:0061649///ubiquitin modification-dependent histone binding+++GO:0008234///cysteine-type peptidase activity","GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0006508///proteolysis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030509///BMP signaling pathway+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0016579///protein deubiquitination","ubiquitin specific peptidase 15","[UBP15_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 15; EC=3.4.19.12 {ECO:0000269|PubMed:10444327, ECO:0000269|PubMed:16005295, ECO:0000269|PubMed:21947082, ECO:0000269|PubMed:22344298, ECO:0000269|PubMed:24852371, ECO:0000269|PubMed:27368102}; AltName: Full=Deubiquitinating enzyme 15; AltName: Full=Ubiquitin thioesterase 15; AltName: Full=Ubiquitin-specific-processing protease 15; AltName: Full=Unph-2; AltName: Full=Unph4;+++[F8VVY7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000449563}; Flags: Fragment;+++[F8VZG8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446843}; Flags: Fragment;+++[F8W0H4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447603}; Flags: Fragment;+++[H0YH96_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446559}; Flags: Fragment;+++[H0YHM4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447367}; Flags: Fragment;+++[H0YI26_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448372}; Flags: Fragment;+++[H0YI31_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448393}; Flags: Fragment;+++[Q2NL66_HUMAN|Unreviewed]SubName: Full=USP15 protein {ECO:0000313|EMBL:AAI10909.1};"]
[996,"'CDC27'",952,920,872,914.666666666667,"04111///Cell cycle - yeast+++04113///Meiosis - yeast+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0005680///anaphase-promoting complex+++GO:0005876///spindle microtubule+++GO:0016021///integral component of membrane+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019903///protein phosphatase binding+++GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0008283///cell proliferation+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle","cell division cycle 27","[CDC27_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 27 homolog; AltName: Full=Anaphase-promoting complex subunit 3; Short=APC3; AltName: Full=CDC27 homolog; Short=CDC27Hs; AltName: Full=H-NUC;+++[B4DL80_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57525, highly similar to Cell division cycle protein 27 homolog {ECO:0000313|EMBL:BAG59442.1};+++[E9PRZ6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432211};+++[F6QPS0_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432105};+++[G5EA36_HUMAN|Unreviewed]SubName: Full=Cell division cycle 27, isoform CRA_c {ECO:0000313|EMBL:EAW57688.1}; SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000437339};+++[I0EZ68_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24904.1}; Flags: Fragment;+++[I0EZ72_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24908.1}; Flags: Fragment;+++[I3L1K3_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000458904}; Flags: Fragment;+++[I3L225_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000459307}; Flags: Fragment;+++[I3L2Z8_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460061}; Flags: Fragment;+++[I3L328_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460132}; Flags: Fragment;+++[I3L394_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460279}; Flags: Fragment;+++[I3L3G1_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460424}; Flags: Fragment;+++[I3L3H6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460454}; Flags: Fragment;+++[I3L3Y5_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460830}; Flags: Fragment;+++[K7EMA6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000466424};"]
[9960,"'USP3'",251,346,300,299,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005654///nucleoplasm+++GO:0090543///Flemming body+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0016787///hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:1990841///promoter-specific chromatin binding+++GO:0008234///cysteine-type peptidase activity","GO:0006281///DNA repair+++GO:0031647///regulation of protein stability+++GO:0016578///histone deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0006508///proteolysis+++GO:0000122///negative regulation of transcription by RNA polymerase II","ubiquitin specific peptidase 3","[UBP3_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 3; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 3; AltName: Full=Ubiquitin thioesterase 3; AltName: Full=Ubiquitin-specific-processing protease 3;+++[H0YKU8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000452947}; Flags: Fragment;+++[H0YL81_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453093}; Flags: Fragment;+++[H0YLB7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453138};+++[H0YLG0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453194}; Flags: Fragment;+++[H0YLJ0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453228};+++[H0YM72_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453489}; Flags: Fragment;+++[H0YMI4_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};+++[H0YMP6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453688}; Flags: Fragment;+++[H0YMW1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453767};+++[H0YNK1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454043};+++[H0YNX9_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454197}; Flags: Fragment;+++[Q498Y2_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305}; Flags: Fragment;+++[Q6JHV3_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};"]
[9961,"'MVP'",3148,2915,3086,3049.66666666667,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00562///Inositol phosphate metabolism+++00564///Glycerophospholipid metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0034774///secretory granule lumen","GO:0042802///identical protein binding+++GO:0030246///carbohydrate binding+++GO:0030145///manganese ion binding+++GO:0019901///protein kinase binding+++GO:0019992///diacylglycerol binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity+++GO:0019903///protein phosphatase binding+++GO:0043178///alcohol binding","GO:0031953///negative regulation of protein autophosphorylation+++GO:0046341///CDP-diacylglycerol metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0023057///negative regulation of signaling+++GO:0015031///protein transport+++GO:0038127///ERBB signaling pathway+++GO:0051028///mRNA transport+++GO:0043312///neutrophil degranulation+++GO:0061099///negative regulation of protein tyrosine kinase activity","major vault protein","[MVP_HUMAN|Reviewed]RecName: Full=Major vault protein; Short=MVP; AltName: Full=Lung resistance-related protein;+++[Q6LAF4_HUMAN|Unreviewed]SubName: Full=LRP protein {ECO:0000313|EMBL:CAA77211.1}; Flags: Fragment;+++[X5D2M8_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform A {ECO:0000313|EMBL:AHW56524.1}; SubName: Full=Major vault protein, isoform CRA_c {ECO:0000313|EMBL:EAW79981.1}; SubName: Full=Testicular secretory protein Li 30 {ECO:0000313|EMBL:AEE61167.1}; Flags: Fragment;+++[X5D7K9_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform C {ECO:0000313|EMBL:AHW56525.1}; Flags: Fragment;+++[X5DNU0_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform B {ECO:0000313|EMBL:AHW56526.1}; Flags: Fragment;"]
[9962,"'SLC23A2'",1799,2578,2030,2135.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0009925///basal plasma membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0070890///sodium-dependent L-ascorbate transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015205///nucleobase transmembrane transporter activity","GO:0006979///response to oxidative stress+++GO:0019852///L-ascorbic acid metabolic process+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0015851///nucleobase transport","solute carrier family 23 member 2","[S23A2_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 2; AltName: Full=Na(+)/L-ascorbic acid transporter 2; AltName: Full=Nucleobase transporter-like 1 protein; AltName: Full=Sodium-dependent vitamin C transporter 2; Short=hSVCT2; AltName: Full=Yolk sac permease-like molecule 2;+++[A0A140VK48_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_b {ECO:0000313|EMBL:EAX10439.1}; SubName: Full=Testicular secretory protein Li 48 {ECO:0000313|EMBL:AEE61185.1};"]
[9963,"'SLC23A1'",1,6,0,2.33333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043229///intracellular organelle+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005737///cytoplasm+++GO:0043292///contractile fiber+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008520///L-ascorbate:sodium symporter activity+++GO:0005215///transporter activity+++GO:0015293///symporter activity+++GO:0005515///protein binding+++GO:0070890///sodium-dependent L-ascorbate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity+++GO:0015205///nucleobase transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015081///sodium ion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0035725///sodium ion transmembrane transport+++GO:0009636///response to toxic substance+++GO:0070837///dehydroascorbic acid transport+++GO:0006811///ion transport+++GO:0019852///L-ascorbic acid metabolic process+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0015851///nucleobase transport+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0006814///sodium ion transport+++GO:0030324///lung development","solute carrier family 23 member 1","[S23A1_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 1; AltName: Full=Na(+)/L-ascorbic acid transporter 1; AltName: Full=Sodium-dependent vitamin C transporter 1; Short=hSVCT1; AltName: Full=Yolk sac permease-like molecule 3;+++[D3DVZ8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_a {ECO:0000313|EMBL:EAX10440.1};+++[H0Y544_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 2 {ECO:0000313|Ensembl:ENSP00000396364}; Flags: Fragment;+++[H0Y902_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|Ensembl:ENSP00000422688}; Flags: Fragment;+++[H0YAJ1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|Ensembl:ENSP00000427271}; Flags: Fragment;+++[Q4ZGM1_HUMAN|Unreviewed]SubName: Full=Sodium-dependent vitamin C transporter 2 variant II {ECO:0000313|EMBL:AAY26157.1}; Flags: Fragment;"]
[9966,"'TNFSF15'",0,0,2.97,0.99,"04060///Cytokine-cytokine receptor interaction","H00286///Crohn's disease",null,null,"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0010469///regulation of signaling receptor activity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006915///apoptotic process+++GO:0042107///cytokine metabolic process+++GO:0006955///immune response+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007165///signal transduction","TNF superfamily member 15","[TNF15_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 15; AltName: Full=TNF ligand-related molecule 1; AltName: Full=Vascular endothelial cell growth inhibitor; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, membrane form; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, secreted form;+++[A0A0U5JA19_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 1B {ECO:0000313|EMBL:CTQ86078.1};+++[D9N2U0_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor (Ligand) superfamily, member 15 {ECO:0000313|EMBL:BAJ13472.1}; Flags: Fragment;+++[X6R8I9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 15 {ECO:0000313|Ensembl:ENSP00000363156};"]
[9967,"'THRAP3'",1984,2212,1991,2062.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0003723///RNA binding+++GO:0042809///vitamin D receptor binding+++GO:0005515///protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0051219///phosphoprotein binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0038023///signaling receptor activity+++GO:0005524///ATP binding+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042753///positive regulation of circadian rhythm+++GO:0048255///mRNA stabilization+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0048511///rhythmic process+++GO:0008380///RNA splicing+++GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","thyroid hormone receptor associated protein 3","[TR150_HUMAN|Reviewed]RecName: Full=Thyroid hormone receptor-associated protein 3; AltName: Full=BCLAF1 and THRAP3 family member 2 {ECO:0000312|HGNC:HGNC:22964}; AltName: Full=Thyroid hormone receptor-associated protein complex 150 kDa component; Short=Trap150;+++[E9PML1_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor-associated protein 3 {ECO:0000313|Ensembl:ENSP00000433066}; Flags: Fragment;+++[Q05D20_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH19076.1}; Flags: Fragment;+++[Q6P0P7_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH65519.1}; Flags: Fragment;+++[Q6PJV4_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH10997.1}; Flags: Fragment;+++[Q7Z5U1_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH54046.1}; Flags: Fragment;"]
[9968,"'MED12'",1143,1494,1238,1291.66666666667,"04919///Thyroid hormone signaling pathway","H01640///Uterine leiomyoma+++H00894///FG syndrome (FGS)+++H00889///MED12-related disorders+++H01795///Blepharophimosis-mental retardation syndrome (BMRS)",null,null,"GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:1904115///axon cytoplasm+++GO:0005829///cytosol+++GO:0016592///mediator complex+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion","GO:0003682///chromatin binding+++GO:1901612///cardiolipin binding+++GO:0016787///hydrolase activity+++GO:0008017///microtubule binding+++GO:0042809///vitamin D receptor binding+++GO:0008289///lipid binding+++GO:0019904///protein domain specific binding+++GO:0070300///phosphatidic acid binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008134///transcription factor binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000287///magnesium ion binding+++GO:0003712///transcription coregulator activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003924///GTPase activity+++GO:0038023///signaling receptor activity+++GO:0019900///kinase binding+++GO:0005525///GTP binding+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0046966///thyroid hormone receptor binding","GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051602///response to electrical stimulus+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0050896///response to stimulus+++GO:0006915///apoptotic process+++GO:0014003///oligodendrocyte development+++GO:0007601///visual perception+++GO:0090398///cellular senescence+++GO:0008053///mitochondrial fusion+++GO:0048312///intracellular distribution of mitochondria+++GO:0007568///aging+++GO:0019896///axonal transport of mitochondrion+++GO:0090102///cochlea development+++GO:0060070///canonical Wnt signaling pathway+++GO:0021510///spinal cord development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0070584///mitochondrion morphogenesis+++GO:0048568///embryonic organ development+++GO:0036342///post-anal tail morphogenesis+++GO:0019827///stem cell population maintenance+++GO:0030521///androgen receptor signaling pathway+++GO:0097749///membrane tubulation+++GO:0036444///calcium import into the mitochondrion+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000002///mitochondrial genome maintenance+++GO:0016567///protein ubiquitination+++GO:0021915///neural tube development+++GO:0071333///cellular response to glucose stimulus+++GO:0007492///endoderm development+++GO:0061025///membrane fusion+++GO:0051259///protein complex oligomerization+++GO:0001843///neural tube closure+++GO:0071456///cellular response to hypoxia+++GO:0060041///retina development in camera-type eye+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0046039///GTP metabolic process+++GO:1900006///positive regulation of dendrite development+++GO:0090245///axis elongation involved in somitogenesis+++GO:0007507///heart development+++GO:0000266///mitochondrial fission+++GO:1990403///embryonic brain development+++GO:1900078///positive regulation of cellular response to insulin stimulus+++GO:0007007///inner mitochondrial membrane organization+++GO:0014044///Schwann cell development+++GO:0014850///response to muscle activity+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:1905232///cellular response to L-glutamate+++GO:0031667///response to nutrient levels+++GO:0001756///somitogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1904643///response to curcumin+++GO:0043066///negative regulation of apoptotic process+++GO:0014042///positive regulation of neuron maturation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0007005///mitochondrion organization+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0010636///positive regulation of mitochondrial fusion","mediator complex subunit 12","[MED12_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 12; AltName: Full=Activator-recruited cofactor 240 kDa component; Short=ARC240; AltName: Full=CAG repeat protein 45; AltName: Full=Mediator complex subunit 12; AltName: Full=OPA-containing protein; AltName: Full=Thyroid hormone receptor-associated protein complex 230 kDa component; Short=Trap230; AltName: Full=Trinucleotide repeat-containing gene 11 protein;+++[A0A2R8Y3X5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493673};+++[A0A2R8Y4G4_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494015}; Flags: Fragment;+++[A0A2R8Y4Q3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493988};+++[A0A2R8Y514_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494210};+++[A0A2R8Y5E2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494736}; Flags: Fragment;+++[A0A2R8Y5G3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494509};+++[A0A2R8YD53_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494273};+++[A0A2R8YDM2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494725};+++[A0A2R8YE54_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495289};+++[A0A2R8YE78_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494121};+++[A0A2R8YFD1_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495028}; Flags: Fragment;+++[A0A2R8YGE5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495943}; Flags: Fragment;+++[A8MXB6_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376232}; Flags: Fragment;+++[C9JMB8_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376231};+++[C9JY58_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000399877}; Flags: Fragment;+++[G0KYB4_HUMAN|Unreviewed]SubName: Full=Putative mediator subunit 12 short {ECO:0000313|EMBL:CAZ90628.1}; Flags: Fragment;+++[H7C141_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000398358}; Flags: Fragment;+++[H7C191_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000399084}; Flags: Fragment;+++[H7C274_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000404373}; Flags: Fragment;+++[H7C321_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000409084}; Flags: Fragment;+++[H7C3G2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000411699}; Flags: Fragment;+++[Q7Z2E0_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81050.1}; Flags: Fragment;+++[Q7Z2F1_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81080.1}; Flags: Fragment;+++[Q7Z2F4_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81020.1}; Flags: Fragment;+++[Q7Z2K3_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81092.1}; Flags: Fragment;+++[Q7Z3Z5_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000333125}; SubName: Full=Mediator of RNA polymerase II transcription, subunit 12 homolog (Yeast), isoform CRA_e {ECO:0000313|EMBL:EAX05318.1}; SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81137.1};+++[Q8WWP6_HUMAN|Unreviewed]SubName: Full=OPA-containing protein {ECO:0000313|EMBL:CAC84084.1}; Flags: Fragment;"]
[9969,"'MED13'",744,738,670,717.333333333333,"04919///Thyroid hormone signaling pathway","H00550///Complete transposition of the great arteries",null,null,"GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003713///transcription coactivator activity+++GO:0042809///vitamin D receptor binding+++GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:1904168///negative regulation of thyroid hormone receptor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030521///androgen receptor signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0070328///triglyceride homeostasis+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006357///regulation of transcription by RNA polymerase II","mediator complex subunit 13","[MED13_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13; AltName: Full=Activator-recruited cofactor 250 kDa component; Short=ARC250; AltName: Full=Mediator complex subunit 13; AltName: Full=Thyroid hormone receptor-associated protein 1; AltName: Full=Thyroid hormone receptor-associated protein complex 240 kDa component; Short=Trap240; AltName: Full=Vitamin D3 receptor-interacting protein complex component DRIP250; Short=DRIP250;+++[A0A024QZ75_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000256|RuleBase:RU364134};+++[J3QRB7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000313|Ensembl:ENSP00000464131}; Flags: Fragment;"]
[997,"'CDC34'",1103,911,967,993.666666666667,"04120///Ubiquitin mediated proteolysis+++05168///Herpes simplex infection",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0005515///protein binding","GO:0035458///cellular response to interferon-beta+++GO:0006270///DNA replication initiation+++GO:0090261///positive regulation of inclusion body assembly+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0070848///response to growth factor+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0000209///protein polyubiquitination+++GO:0006464///cellular protein modification process+++GO:0007049///cell cycle","cell division cycle 34","[UB2R1_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 R1; EC=2.3.2.23 {ECO:0000269|PubMed:12037680, ECO:0000269|PubMed:17698585, ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:20347421}; AltName: Full=(E3-independent) E2 ubiquitin-conjugating enzyme R1; EC=2.3.2.24 {ECO:0000269|PubMed:17588522}; AltName: Full=E2 ubiquitin-conjugating enzyme R1; AltName: Full=Ubiquitin-conjugating enzyme E2-32 kDa complementing; AltName: Full=Ubiquitin-conjugating enzyme E2-CDC34; AltName: Full=Ubiquitin-protein ligase R1;+++[A0A024R1Z1_HUMAN|Unreviewed]SubName: Full=Cell division cycle 34, isoform CRA_a {ECO:0000313|EMBL:EAW61191.1};+++[U3KPV8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475282}; Flags: Fragment;+++[U3KQ77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475610}; Flags: Fragment;+++[U3KQP9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000476107}; Flags: Fragment;"]
[9970,"'NR1I3'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0004882///androgen receptor activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding+++GO:0008134///transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004887///thyroid hormone receptor activity+++GO:0003707///steroid hormone receptor activity","GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030521///androgen receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","nuclear receptor subfamily 1 group I member 3","[NR1I3_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group I member 3; AltName: Full=Constitutive activator of retinoid response; Short=Constitutive active response; AltName: Full=Constitutive androstane receptor; Short=CAR; AltName: Full=Orphan nuclear receptor MB67;+++[B6ZGT2_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor {ECO:0000313|EMBL:BAH02293.1};+++[B7Z8R7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000427034}; SubName: Full=cDNA FLJ56764, highly similar to Orphan nuclear receptor NR1I3 {ECO:0000313|EMBL:BAH14053.1}; SubName: Full=cDNA, FLJ79107, highly similar to Orphan nuclear receptor NR1I3 {ECO:0000313|EMBL:BAH14579.1};+++[C0H5Y2_HUMAN|Unreviewed]SubName: Full=NR1I3 protein {ECO:0000313|EMBL:AAH69651.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000424834}; SubName: Full=Nuclear receptor subfamily 1, group I, member 3, isoform CRA_c {ECO:0000313|EMBL:EAW52610.1};+++[D6REZ7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000421588};+++[E9PCF2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000423089};+++[F1DAL4_HUMAN|Unreviewed]SubName: Full=Constitutive androstane nuclear receptor {ECO:0000313|EMBL:ADZ17385.1};+++[Q6GZ69_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV21 {ECO:0000313|EMBL:AAT47179.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000426016};+++[Q6GZ70_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV19 {ECO:0000313|EMBL:AAT47177.1}; SubName: Full=Constitutive androstane receptor SV20 {ECO:0000313|EMBL:AAT47178.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000422982};+++[Q6GZ72_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV17 {ECO:0000313|EMBL:AAT47175.1}; SubName: Full=Constitutive androstane receptor SV18 {ECO:0000313|EMBL:AAT47176.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000421374};+++[Q6GZ74_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV16 {ECO:0000313|EMBL:AAT47174.1}; Flags: Fragment;+++[Q6GZ75_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV15 {ECO:0000313|EMBL:AAT47173.1}; Flags: Fragment;+++[Q6GZ81_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV10 {ECO:0000313|EMBL:AAT47168.1}; SubName: Full=Constitutive androstane receptor SV4 {ECO:0000313|EMBL:AAT47162.1}; SubName: Full=Constitutive androstane receptor SV9 {ECO:0000313|EMBL:AAT47167.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000423007};+++[Q6GZ88_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV2 {ECO:0000313|EMBL:AAT47160.1};"]
[9972,"'NUP153'",760,811,763,778,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005634///nucleus+++GO:0005623///cell+++GO:0005730///nucleolus+++GO:0005643///nuclear pore+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0043657///host cell+++GO:0044613///nuclear pore central transport channel+++GO:0034399///nuclear periphery+++GO:0044615///nuclear pore nuclear basket+++GO:0016020///membrane+++GO:0042405///nuclear inclusion body","GO:0017056///structural constituent of nuclear pore+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0008139///nuclear localization sequence binding","GO:0075732///viral penetration into host nucleus+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0046718///viral entry into host cell+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0046832///negative regulation of RNA export from nucleus+++GO:0016032///viral process+++GO:0006913///nucleocytoplasmic transport","nucleoporin 153","[NU153_HUMAN|Reviewed]RecName: Full=Nuclear pore complex protein Nup153; AltName: Full=153 kDa nucleoporin; AltName: Full=Nucleoporin Nup153;+++[A0A024QZW7_HUMAN|Unreviewed]SubName: Full=Nucleoporin 153kDa, isoform CRA_a {ECO:0000313|EMBL:EAW55385.1};"]
[9973,"'CCS'",244,248,247,246.333333333333,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004784///superoxide dismutase activity+++GO:0016532///superoxide dismutase copper chaperone activity","GO:0015680///protein maturation by copper ion transfer+++GO:0034599///cellular response to oxidative stress+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0055114///oxidation-reduction process+++GO:0006801///superoxide metabolic process+++GO:0019430///removal of superoxide radicals+++GO:0030001///metal ion transport","copper chaperone for superoxide dismutase","[CCS_HUMAN|Reviewed]RecName: Full=Copper chaperone for superoxide dismutase; AltName: Full=Superoxide dismutase copper chaperone;+++[A0A024R5B4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase, isoform CRA_a {ECO:0000313|EMBL:EAW74551.1};+++[E9PK03_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000433609};+++[E9PP76_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000436379}; Flags: Fragment;+++[J3KNF4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000307870};"]
[9975,"'NR1D2'",329,391,324,348,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex","GO:0038023///signaling receptor activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003707///steroid hormone receptor activity","GO:0042752///regulation of circadian rhythm+++GO:0050727///regulation of inflammatory response+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0033993///response to lipid+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0048511///rhythmic process+++GO:0097009///energy homeostasis+++GO:0030154///cell differentiation+++GO:0019216///regulation of lipid metabolic process+++GO:0009755///hormone-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0055088///lipid homeostasis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030522///intracellular receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0043401///steroid hormone mediated signaling pathway","nuclear receptor subfamily 1 group D member 2","[NR1D2_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group D member 2; AltName: Full=Orphan nuclear hormone receptor BD73; AltName: Full=Rev-erb alpha-related receptor; Short=RVR; AltName: Full=Rev-erb-beta; AltName: Full=V-erbA-related protein 1-related; Short=EAR-1R;+++[B4DXD3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 2 {ECO:0000313|EMBL:ADZ17342.1}; SubName: Full=Nuclear receptor subfamily 1, group D, member 2, isoform CRA_b {ECO:0000313|EMBL:EAW64341.1}; SubName: Full=cDNA FLJ51368, highly similar to Orphan nuclear receptor NR1D2 {ECO:0000313|EMBL:BAG63345.1};+++[B6ZGS3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1, group D, member 2 {ECO:0000313|EMBL:BAH02284.1};+++[F1D8P2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 1 {ECO:0000313|EMBL:ADZ17341.1};+++[Q6I9S1_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:CAG33715.1};+++[Q6NSM0_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH70035.1}; SubName: Full=Nuclear receptor subfamily 1 group D member 2 {ECO:0000313|Ensembl:ENSP00000373283};+++[Q96B66_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH15929.1}; Flags: Fragment;"]
[9978,"'RBX1'",452,373,388,404.333333333333,"04110///Cell cycle+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++04114///Oocyte meiosis+++03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04310///Wnt signaling pathway+++04341///Hedgehog signaling pathway - fly+++05200///Pathways in cancer+++04710///Circadian rhythm+++04350///TGF-beta signaling pathway+++04111///Cell cycle - yeast",null,"M00385///Cul4-DDB1-DDB2 complex+++M00407///SCF-CDC4 complex+++M00381///SCF-SKP2 complex+++M00411///SCF-GRR1 complex+++M00383///ECV complex+++M00382///SCF-FBS complex+++M00386///Cul4-DDB1-CSA complex+++M00380///SCF-BTRC complex+++M00387///SCF-FBW7 complex+++M00384///Cul3-SPOP complex+++M00379///SCF-MET30 complex",null,"GO:0005654///nucleoplasm+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0030891///VCB complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043224///nuclear SCF ubiquitin ligase complex","GO:0044877///protein-containing complex binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008134///transcription factor binding+++GO:0019788///NEDD8 transferase activity+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0046872///metal ion binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0097602///cullin family protein binding+++GO:0061630///ubiquitin protein ligase activity","GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0070911///global genome nucleotide-excision repair+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016032///viral process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006281///DNA repair+++GO:0010265///SCF complex assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006513///protein monoubiquitination+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0043687///post-translational protein modification+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0045116///protein neddylation+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000209///protein polyubiquitination+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000165///MAPK cascade+++GO:0030163///protein catabolic process","ring-box 1","[RBX1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RBX1; EC=2.3.2.27 {ECO:0000269|PubMed:11027288}; EC=2.3.2.32 {ECO:0000269|PubMed:11027288}; AltName: Full=E3 ubiquitin-protein transferase RBX1 {ECO:0000305}; AltName: Full=Protein ZYP; AltName: Full=RING finger protein 75; AltName: Full=RING-box protein 1; Short=Rbx1; AltName: Full=Regulator of cullins 1; Short=ROC1 {ECO:0000303|PubMed:10230407}; Contains: RecName: Full=E3 ubiquitin-protein ligase RBX1, N-terminally processed; AltName: Full=E3 ubiquitin-protein transferase RBX1, N-terminally processed {ECO:0000305};"]
[998,"'CDC42'",3273,2681,2863,2939,"05131///Shigellosis+++05211///Renal cell carcinoma+++04062///Chemokine signaling pathway+++04530///Tight junction+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04810///Regulation of actin cytoskeleton+++05132///Salmonella infection+++05130///Pathogenic Escherichia coli infection+++05205///Proteoglycans in cancer+++04360///Axon guidance+++05165///Human papillomavirus infection+++05212///Pancreatic cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer+++04520///Adherens junction+++04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04011///MAPK signaling pathway - yeast+++04722///Neurotrophin signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++04912///GnRH signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04014///Ras signaling pathway+++05203///Viral carcinogenesis+++04144///Endocytosis+++04010///MAPK signaling pathway+++04370///VEGF signaling pathway+++04660///T cell receptor signaling pathway",{"$nulls":3},"GO:0045335///phagocytic vesicle+++GO:0043005///neuron projection+++GO:0005813///centrosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0030496///midbody+++GO:0000139///Golgi membrane+++GO:0045177///apical part of cell+++GO:0031256///leading edge membrane+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0070062///extracellular exosome+++GO:0005819///spindle+++GO:0051233///spindle midzone+++GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0000322///storage vacuole+++GO:0030175///filopodium+++GO:0017119///Golgi transport complex+++GO:0072686///mitotic spindle+++GO:0032991///protein-containing complex+++GO:0071944///cell periphery","GO:0004674///protein serine/threonine kinase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0005525///GTP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0031996///thioesterase binding+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0030742///GTP-dependent protein binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0032427///GBD domain binding+++GO:0019901///protein kinase binding","GO:0048013///ephrin receptor signaling pathway+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007097///nuclear migration+++GO:0060047///heart contraction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0072384///organelle transport along microtubule+++GO:0007163///establishment or maintenance of cell polarity+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0030154///cell differentiation+++GO:0031295///T cell costimulation+++GO:0090316///positive regulation of intracellular protein transport+++GO:0030031///cell projection assembly+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0030307///positive regulation of cell growth+++GO:0051489///regulation of filopodium assembly+++GO:0060997///dendritic spine morphogenesis+++GO:0031333///negative regulation of protein complex assembly+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090135///actin filament branching+++GO:0036336///dendritic cell migration+++GO:0007266///Rho protein signal transduction+++GO:0043497///regulation of protein heterodimerization activity+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0006897///endocytosis+++GO:0007088///regulation of mitotic nuclear division+++GO:0016567///protein ubiquitination+++GO:0006468///protein phosphorylation+++GO:0051491///positive regulation of filopodium assembly+++GO:0051492///regulation of stress fiber assembly+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0032467///positive regulation of cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0099563///modification of synaptic structure+++GO:0046330///positive regulation of JNK cascade+++GO:0034332///adherens junction organization+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0034613///cellular protein localization+++GO:0034329///cell junction assembly+++GO:0007399///nervous system development+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0045740///positive regulation of DNA replication+++GO:0007596///blood coagulation+++GO:0032488///Cdc42 protein signal transduction+++GO:0048664///neuron fate determination+++GO:0007229///integrin-mediated signaling pathway+++GO:0021762///substantia nigra development+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0051647///nucleus localization+++GO:0051835///positive regulation of synapse structural plasticity+++GO:0007030///Golgi organization+++GO:0010591///regulation of lamellipodium assembly+++GO:0030225///macrophage differentiation+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0046847///filopodium assembly+++GO:0051683///establishment of Golgi localization+++GO:0008360///regulation of cell shape+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0003161///cardiac conduction system development+++GO:0007264///small GTPase mediated signal transduction+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0051301///cell division+++GO:0038189///neuropilin signaling pathway+++GO:0002040///sprouting angiogenesis+++GO:0060661///submandibular salivary gland formation+++GO:0043085///positive regulation of catalytic activity","cell division cycle 42","[CDC42_HUMAN|Reviewed]RecName: Full=Cell division control protein 42 homolog; AltName: Full=G25K GTP-binding protein; Flags: Precursor;+++[A0A024RAE4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a {ECO:0000313|EMBL:EAW95004.1};+++[A0A024RAE6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_c {ECO:0000313|EMBL:EAW95009.1};+++[Q5JYX0_HUMAN|Unreviewed]SubName: Full=Cell division control protein 42 homolog {ECO:0000313|Ensembl:ENSP00000398327}; Flags: Fragment;"]
[9980,"'DOP1B'",314.87,245,281.55,280.473333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0005802///trans-Golgi network+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0050890///cognition+++GO:0007275///multicellular organism development+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","DOP1 leucine zipper like protein B","[DOP2_HUMAN|Reviewed]RecName: Full=Protein dopey-2;+++[F8W8U9_HUMAN|Unreviewed]SubName: Full=DOP1 leucine zipper-like protein B {ECO:0000313|Ensembl:ENSP00000270190}; Flags: Fragment;"]
[9982,"'FGFBP1'",0,1,3,1.33333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0005576///extracellular region","GO:0017134///fibroblast growth factor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0019838///growth factor binding","GO:0008285///negative regulation of cell proliferation+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007267///cell-cell signaling+++GO:0007165///signal transduction","fibroblast growth factor binding protein 1","[FGFP1_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor-binding protein 1; Short=FGF-BP; Short=FGF-BP1; Short=FGF-binding protein 1; Short=FGFBP-1; AltName: Full=17 kDa heparin-binding growth factor-binding protein; Short=17 kDa HBGF-binding protein; Short=HBp17; Flags: Precursor;"]
[9984,"'THOC1'",133,158,120,137,"03040///Spliceosome+++03013///RNA transport",null,"M00405///THC complex+++M00406///TREX complex",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0000347///THO complex+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000445///THO complex part of transcription export complex+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0000346///transcription export complex+++GO:0016607///nuclear speck","GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0051028///mRNA transport+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0006406///mRNA export from nucleus+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0007165///signal transduction+++GO:0008380///RNA splicing+++GO:0031297///replication fork processing+++GO:0006396///RNA processing+++GO:0000018///regulation of DNA recombination+++GO:0048297///negative regulation of isotype switching to IgA isotypes+++GO:0031124///mRNA 3'-end processing","THO complex 1","[THOC1_HUMAN|Reviewed]RecName: Full=THO complex subunit 1; Short=Tho1; AltName: Full=Nuclear matrix protein p84; Short=p84N5; AltName: Full=hTREX84;+++[A0A087WWS1_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000480460};+++[A0A087WY84_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000481599};+++[J3KRD7_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000461943};+++[J3KT14_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000462757};+++[J3QQZ3_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000463965};+++[R4GMN4_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473276}; Flags: Fragment;+++[R4GN58_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473499}; Flags: Fragment;"]
[9985,"'REC8'",6471,6311,6213,6331.66666666667,"04114///Oocyte meiosis",{"$nulls":3},"GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0030893///meiotic cohesin complex+++GO:0000800///lateral element+++GO:0005694///chromosome+++GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000795///synaptonemal complex+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0008278///cohesin complex+++GO:0001673///male germ cell nucleus+++GO:0034991///nuclear meiotic cohesin complex","GO:0003682///chromatin binding","GO:0007130///synaptonemal complex assembly+++GO:0009566///fertilization+++GO:0000724///double-strand break repair via homologous recombination+++GO:0007059///chromosome segregation+++GO:0007141///male meiosis I+++GO:0007062///sister chromatid cohesion+++GO:0072520///seminiferous tubule development+++GO:0007283///spermatogenesis+++GO:0001556///oocyte maturation+++GO:0051321///meiotic cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0007286///spermatid development+++GO:0006302///double-strand break repair+++GO:0007129///synapsis","REC8 meiotic recombination protein","[REC8_HUMAN|Reviewed]RecName: Full=Meiotic recombination protein REC8 homolog; AltName: Full=Cohesin Rec8p;+++[A0A075B715_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000452701}; Flags: Fragment;+++[H0YM87_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453506}; Flags: Fragment;+++[H0YMV7_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453763}; Flags: Fragment;"]
[9986,"'RCE1'",178,167,173,172.666666666667,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis",null,null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0016787///hydrolase activity","GO:0071586///CAAX-box protein processing+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","Ras converting CAAX endopeptidase 1","[FACE2_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 2; EC=3.4.22.-; AltName: Full=Farnesylated proteins-converting enzyme 2; Short=FACE-2; AltName: Full=Prenyl protein-specific endoprotease 2; AltName: Full=RCE1 homolog; Short=hRCE1;+++[A0A024R5B6_HUMAN|Unreviewed]SubName: Full=RCE1 homolog, prenyl protein peptidase (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW74566.1};+++[E9PI08_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436600};+++[E9PKA7_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000435409};+++[E9PPV9_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436300};+++[Q0P5W4_HUMAN|Unreviewed]SubName: Full=RCE1 protein {ECO:0000313|EMBL:AAH52622.1}; Flags: Fragment;"]
[9987,"'HNRNPDL'",1293,1342,1158,1264.33333333333,null,"H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005681///spliceosomal complex+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0043565///sequence-specific DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0034046///poly(G) binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0008143///poly(A) binding","GO:0010468///regulation of gene expression+++GO:0006396///RNA processing+++GO:0035722///interleukin-12-mediated signaling pathway","heterogeneous nuclear ribonucleoprotein D like","[HNRDL_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like; Short=hnRNP D-like; Short=hnRNP DL; AltName: Full=AU-rich element RNA-binding factor; AltName: Full=JKT41-binding protein; AltName: Full=Protein laAUF1;+++[A0A024RDF6_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_a {ECO:0000313|EMBL:EAX05891.1};+++[A0A087WU03_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like {ECO:0000313|Ensembl:ENSP00000478269};+++[A0A087WUK2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_b {ECO:0000313|EMBL:EAX05890.1};"]
[9988,"'DMTF1'",363,404,382,383,{"$nulls":4},"GO:0005829///cytosol+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0005654///nucleoplasm+++GO:0005576///extracellular region","GO:0003700///DNA-binding transcription factor activity+++GO:0005178///integrin binding+++GO:0003677///DNA binding+++GO:0005509///calcium ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0050840///extracellular matrix binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0070173///regulation of enamel mineralization+++GO:0031214///biomineral tissue development+++GO:0043687///post-translational protein modification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030198///extracellular matrix organization+++GO:0007049///cell cycle+++GO:0044267///cellular protein metabolic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0001503///ossification+++GO:0006355///regulation of transcription, DNA-templated","cyclin D binding myb like transcription factor 1","[DMTF1_HUMAN|Reviewed]RecName: Full=Cyclin-D-binding Myb-like transcription factor 1; Short=hDMTF1; AltName: Full=Cyclin-D-interacting Myb-like protein 1; Short=hDMP1;+++[A0A1D5RMP8_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000406384}; Flags: Fragment;+++[B3KMJ8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ11211 fis, clone PLACE1007955, highly similar to Homo sapiens cyclin D binding myb-like transcription factor 1 (DMTF1), mRNA {ECO:0000313|EMBL:BAG51010.1};+++[C9J4F7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000411858}; Flags: Fragment;+++[C9J8Y5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000397490}; Flags: Fragment;+++[C9JED5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000415382}; Flags: Fragment;+++[C9JFR2_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416499}; Flags: Fragment;+++[C9JGT5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416307}; Flags: Fragment;+++[C9JLR5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413722}; Flags: Fragment;+++[C9JVQ7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000393370}; Flags: Fragment;+++[C9JZZ6_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000387712}; Flags: Fragment;+++[C9K0K9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413118}; Flags: Fragment;+++[C9K0L9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000401129}; Flags: Fragment;+++[D6W5P0_HUMAN|Unreviewed]SubName: Full=Cyclin D binding myb-like transcription factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW76964.1};+++[E7EPA0_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000402627};+++[F8VXY9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000448775};+++[H7C388_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000410288}; Flags: Fragment;+++[J3KRC1_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000461920}; Flags: Fragment;+++[J3QKU5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463239}; Flags: Fragment;+++[J3QLN9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463638};+++[J3QLW3_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463735}; Flags: Fragment;"]
[9989,"'PPP4R1'",825,719,741,761.666666666667,"05200///Pathways in cancer+++05212///Pancreatic cancer+++04014///Ras signaling pathway",{"$nulls":3},"GO:0030289///protein phosphatase 4 complex","GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0050790///regulation of catalytic activity","protein phosphatase 4 regulatory subunit 1","[PP4R1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1;+++[F8WAJ9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000285124};+++[J3KRU1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462161}; Flags: Fragment;+++[J3KSB0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462399}; Flags: Fragment;+++[J3KSH2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462485};+++[J3KSS1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462621};+++[J3QL26_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463345}; Flags: Fragment;+++[J3QLA6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463459}; Flags: Fragment;+++[J3QQV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463909}; Flags: Fragment;+++[J3QRV2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000464394};+++[Q6RXQ6_HUMAN|Unreviewed]SubName: Full=Protein serine/threonine phosphatase 4 subunit {ECO:0000313|EMBL:AAS59409.1}; Flags: Fragment;"]
[999,"'CDH1'",6276,6645,5774,6231.66666666667,"05218///Melanoma+++05219///Bladder cancer+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04390///Hippo signaling pathway+++04371///Apelin signaling pathway+++04015///Rap1 signaling pathway+++05216///Thyroid cancer+++05226///Gastric cancer+++04520///Adherens junction","H00032///Thyroid cancer+++H00025///Penile cancer+++H00054///Nasopharyngeal cancer+++H00018///Gastric cancer",null,null,"GO:0015629///actin cytoskeleton+++GO:0043296///apical junction complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0005913///cell-cell adherens junction+++GO:0005576///extracellular region+++GO:0016600///flotillin complex+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0098794///postsynapse+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016342///catenin complex+++GO:0005802///trans-Golgi network+++GO:0005768///endosome+++GO:0016328///lateral plasma membrane","GO:0050839///cell adhesion molecule binding+++GO:0032794///GTPase activating protein binding+++GO:0005509///calcium ion binding+++GO:0030506///ankyrin binding+++GO:0045296///cadherin binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0071681///cellular response to indole-3-methanol+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0009636///response to toxic substance+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0042307///positive regulation of protein import into nucleus+++GO:0071285///cellular response to lithium ion+++GO:0035635///entry of bacterium into host cell+++GO:0030198///extracellular matrix organization+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0072659///protein localization to plasma membrane+++GO:0031175///neuron projection development","cadherin 1","[CADH1_HUMAN|Reviewed]RecName: Full=Cadherin-1; AltName: Full=CAM 120/80; AltName: Full=Epithelial cadherin; Short=E-cadherin; AltName: Full=Uvomorulin; AltName: CD_antigen=CD324; Contains: RecName: Full=E-Cad/CTF1; Contains: RecName: Full=E-Cad/CTF2; Contains: RecName: Full=E-Cad/CTF3; Flags: Precursor;+++[A0A0U2ZQU7_HUMAN|Unreviewed]SubName: Full=E-cadherin 1 {ECO:0000313|EMBL:ALS87660.1};+++[B3GN61_HUMAN|Unreviewed]SubName: Full=Truncated E-cadherin {ECO:0000313|EMBL:ACD87624.1};+++[Q9UII7_HUMAN|Unreviewed]SubName: Full=E-cadherin {ECO:0000313|EMBL:BAA88957.1};"]
[9990,"'SLC12A6'",295.14,315.95,294,301.696666666667,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00816///Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)+++H01815///Malignant migrating partial seizures in infancy+++H00606///Early infantile epileptic encephalopathy","M00425///H/ACA ribonucleoprotein complex",null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane","GO:0019901///protein kinase binding+++GO:0015377///cation:chloride symporter activity+++GO:0015293///symporter activity+++GO:0015079///potassium ion transmembrane transporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0005215///transporter activity","GO:1902476///chloride transmembrane transport+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0006884///cell volume homeostasis+++GO:0071476///cellular hypotonic response+++GO:0071477///cellular hypotonic salinity response+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0001525///angiogenesis+++GO:0055064///chloride ion homeostasis+++GO:0007268///chemical synaptic transmission+++GO:1990573///potassium ion import across plasma membrane+++GO:0006813///potassium ion transport","solute carrier family 12 member 6","[S12A6_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 6; AltName: Full=Electroneutral potassium-chloride cotransporter 3; AltName: Full=K-Cl cotransporter 3;+++[A0A024R9I5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_d {ECO:0000313|EMBL:EAW92302.1};+++[A0A024R9K8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_a {ECO:0000313|EMBL:EAW92296.1};+++[A7E2U9_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAI50585.1}; Flags: Fragment;+++[B3KXX3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46254 fis, clone TESTI4023096, highly similar to Solute carrier family 12 member 6 {ECO:0000313|EMBL:BAG54635.1};+++[H0YKE6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452771}; Flags: Fragment;+++[H0YKJ2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452828}; Flags: Fragment;+++[H0YKL8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452857}; Flags: Fragment;+++[H0YKQ8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452904};+++[H0YMQ9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_c {ECO:0000313|EMBL:EAW92298.1}; SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000453702};+++[H0YNJ5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000454037}; Flags: Fragment;+++[Q3ZCQ6_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAH51744.1};+++[Q6NSI7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6 {ECO:0000313|EMBL:AAH70107.2};"]
[9991,"'PTBP3'",405,297,327,343,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0030154///cell differentiation+++GO:0043249///erythrocyte maturation+++GO:0006397///mRNA processing+++GO:0033119///negative regulation of RNA splicing+++GO:0008380///RNA splicing+++GO:0045595///regulation of cell differentiation+++GO:0009653///anatomical structure morphogenesis","polypyrimidine tract binding protein 3","[PTBP3_HUMAN|Reviewed]RecName: Full=Polypyrimidine tract-binding protein 3; AltName: Full=Regulator of differentiation 1; Short=Rod1;+++[A0A024R163_HUMAN|Unreviewed]SubName: Full=ROD1 regulator of differentiation 1 (S. pombe), isoform CRA_b {ECO:0000313|EMBL:EAW59101.1};+++[B1ALY4_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000388024}; Flags: Fragment;+++[X6R242_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000210227}; Flags: Fragment;"]
[9992,"'KCNE2'",1,2,0,1,"04971///Gastric acid secretion","H00720///Long QT syndrome+++H00731///Atrial fibrillation",null,null,"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005764///lysosome","GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0015459///potassium channel regulator activity+++GO:0005242///inward rectifier potassium channel activity","GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1902159///regulation of cyclic nucleotide-gated ion channel activity+++GO:0035690///cellular response to drug+++GO:0006813///potassium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086009///membrane repolarization+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0060306///regulation of membrane repolarization+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901979///regulation of inward rectifier potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0034765///regulation of ion transmembrane transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0086011///membrane repolarization during action potential+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:0043586///tongue development+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:0007568///aging+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086091///regulation of heart rate by cardiac conduction","potassium voltage-gated channel subfamily E regulatory subunit 2","[KCNE2_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 2; AltName: Full=MinK-related peptide 1; AltName: Full=Minimum potassium ion channel-related peptide 1; AltName: Full=Potassium channel subunit beta MiRP1;+++[Q2N1I3_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit 2 {ECO:0000313|EMBL:ABB00303.1}; Flags: Fragment;"]
[9993,"'DGCR2'",5548,5717,5207,5490.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0009887///animal organ morphogenesis+++GO:0050890///cognition+++GO:0007155///cell adhesion","DiGeorge syndrome critical region gene 2","[IDD_HUMAN|Reviewed]RecName: Full=Integral membrane protein DGCR2/IDD; Flags: Precursor;+++[B7Z3C4_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2, isoform CRA_c {ECO:0000313|EMBL:EAX03063.1}; SubName: Full=cDNA FLJ50536, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12160.1};+++[B7Z3T5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50553, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12321.1};+++[F6SYP7_HUMAN|Unreviewed]SubName: Full=Integral membrane protein DGCR2/IDD {ECO:0000313|Ensembl:ENSP00000445069};+++[Q5CZ70_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686I1730 {ECO:0000313|EMBL:CAI59783.1};+++[Q8IWC8_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2 {ECO:0000313|EMBL:AAH40500.1};"]
[9994,"'CASP8AP2'",116,123,67,102,"04140///Autophagy - animal+++04137///Mitophagy - animal+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0016605///PML body+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0003714///transcription corepressor activity+++GO:0032184///SUMO polymer binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0002020///protease binding+++GO:0016505///peptidase activator activity involved in apoptotic process+++GO:0005123///death receptor binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0097190///apoptotic signaling pathway+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0036337///Fas signaling pathway+++GO:0006915///apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007049///cell cycle","caspase 8 associated protein 2","[C8AP2_HUMAN|Reviewed]RecName: Full=CASP8-associated protein 2; AltName: Full=FLICE-associated huge protein;+++[A0A087WTW5_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000478179};+++[A0A096LP21_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000485346}; Flags: Fragment;+++[A7E2C0_HUMAN|Unreviewed]SubName: Full=CASP8AP2 protein {ECO:0000313|EMBL:AAI50275.1};+++[L8EC81_HUMAN|Unreviewed]SubName: Full=Alternative protein CASP8AP2 {ECO:0000313|EMBL:CCQ43107.1};"]
[9997,"'SCO2'",212.76,169,166.22,182.66,null,"H01200///Fatal infantile cardioencephalomyopathy+++H02041///Myopia+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005759///mitochondrial matrix+++GO:0030016///myofibril+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane","GO:0005507///copper ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0004645///phosphorylase activity+++GO:0015035///protein disulfide oxidoreductase activity","GO:0045454///cell redox homeostasis+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0006206///pyrimidine nucleobase metabolic process+++GO:0006878///cellular copper ion homeostasis+++GO:0001654///eye development+++GO:0006825///copper ion transport+++GO:0055114///oxidation-reduction process+++GO:0006213///pyrimidine nucleoside metabolic process+++GO:0008535///respiratory chain complex IV assembly","SCO2, cytochrome c oxidase assembly protein","[SCO2_HUMAN|Reviewed]RecName: Full=Protein SCO2 homolog, mitochondrial; Flags: Precursor;+++[A0A1W2PP80_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491034}; Flags: Fragment;+++[A0A1W2PQK0_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491753}; Flags: Fragment;"]

{"sheet":"12 week samples","index":1,"n_rows":16726,"n_cols":15,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["Gene ID","Gene Symbol","12_weeks_1 Read Count","12_weeks_2 Read Count","12_weeks_3 Read Count","12_weeks Average Read Count","KEGG Pathway Desc","KEGG Disease Desc","KEGG Module Desc","KEGG Reaction Desc","GO_C Desc","GO_F Desc","GO_P Desc","GeneBank Desc","UniProt Desc"]
[1,"'A1BG'",122,156,134,137.333333333333,"04380///Osteoclast differentiation",{"$nulls":3},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0031093///platelet alpha granule lumen+++GO:1904813///ficolin-1-rich granule lumen+++GO:0034774///secretory granule lumen+++GO:0062023///collagen-containing extracellular matrix+++GO:0072562///blood microparticle","GO:0003674///molecular_function","GO:0002576///platelet degranulation+++GO:0043312///neutrophil degranulation+++GO:0008150///biological_process","alpha-1-B glycoprotein","[A1BG_HUMAN|Reviewed]RecName: Full=Alpha-1B-glycoprotein; AltName: Full=Alpha-1-B glycoprotein; Flags: Precursor;+++[M0R009_HUMAN|Unreviewed]SubName: Full=Alpha-1B-glycoprotein {ECO:0000313|Ensembl:ENSP00000470909}; Flags: Fragment;+++[V9HWD8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 163pA {ECO:0000313|EMBL:ACJ13639.1};"]
[10,"'NAT2'",0,1,0,0.333333333333333,"00983///Drug metabolism - other enzymes+++05204///Chemical carcinogenesis+++01100///Metabolic pathways+++00633///Nitrotoluene degradation+++00232///Caffeine metabolism+++01110///Biosynthesis of secondary metabolites+++01120///Microbial metabolism in diverse environments",null,null,"R11902///acetyl-CoA:hydrazine N-acetyltransferase   Acetyl-CoA + Hydrazine <=> CoA + Acetylhydrazine+++R07940///1,7-Dimethylxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil+++R08036///acetyl-CoA:2,4-diamino-6-nitrotoluene N-acetyltransferase   2,4-Diamino-6-nitrotoluene + Acetyl-CoA <=> 4-Acetamido-2-amino-6-nitrotoluene + CoA+++R08248///acetyl-CoA: isoniazid N-acetyltransferase   Acetyl-CoA + Isoniazid <=> CoA + N-Acetylisoniazid+++R08250///acetyl-CoA:acetylhydrazine N-acetyltransferase   Acetyl-CoA + Acetylhydrazine <=> CoA + N,N'-Diacetylhydrazine","GO:0005829///cytosol","GO:0004060///arylamine N-acetyltransferase activity","GO:0006805///xenobiotic metabolic process","N-acetyltransferase 2","[ARY2_HUMAN|Reviewed]RecName: Full=Arylamine N-acetyltransferase 2; EC=2.3.1.5; AltName: Full=Arylamide acetylase 2; AltName: Full=N-acetyltransferase type 2; Short=NAT-2; AltName: Full=Polymorphic arylamine N-acetyltransferase; Short=PNAT;+++[A4Z6T7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01136.1};"]
[100,"'ADA'",87,123,88,99.3333333333333,"05340///Primary immunodeficiency+++01100///Metabolic pathways+++00230///Purine metabolism","H00092///T-B-Severe combined immunodeficiencies (SCIDs)",null,"R01560///Adenosine aminohydrolase   Adenosine + H2O <=> Inosine + Ammonia+++R02556///Deoxyadenosine aminohydrolase   Deoxyadenosine + H2O <=> Deoxyinosine + Ammonia","GO:0032839///dendrite cytoplasm+++GO:0030054///cell junction+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0060205///cytoplasmic vesicle lumen+++GO:0005764///lysosome+++GO:0005615///extracellular space+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004000///adenosine deaminase activity+++GO:0001883///purine nucleoside binding+++GO:0019239///deaminase activity","GO:0046061///dATP catabolic process+++GO:0042493///response to drug+++GO:0046111///xanthine biosynthetic process+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0043103///hypoxanthine salvage+++GO:0043066///negative regulation of apoptotic process+++GO:0001889///liver development+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0001701///in utero embryonic development+++GO:0032261///purine nucleotide salvage+++GO:0043101///purine-containing compound salvage+++GO:0030324///lung development+++GO:0002314///germinal center B cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0010460///positive regulation of heart rate+++GO:0050870///positive regulation of T cell activation+++GO:0033197///response to vitamin E+++GO:0001821///histamine secretion+++GO:0045580///regulation of T cell differentiation+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0042542///response to hydrogen peroxide+++GO:0060169///negative regulation of adenosine receptor signaling pathway+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007155///cell adhesion+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046101///hypoxanthine biosynthetic process+++GO:0048541///Peyer's patch development+++GO:0001890///placenta development+++GO:0048566///embryonic digestive tract development+++GO:0009117///nucleotide metabolic process+++GO:0060407///negative regulation of penile erection+++GO:0042110///T cell activation+++GO:0070256///negative regulation of mucus secretion+++GO:0042323///negative regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046103///inosine biosynthetic process+++GO:0002636///positive regulation of germinal center formation+++GO:0050728///negative regulation of inflammatory response+++GO:0048286///lung alveolus development+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0046085///adenosine metabolic process+++GO:0002686///negative regulation of leukocyte migration+++GO:0007568///aging+++GO:0043278///response to morphine+++GO:0045582///positive regulation of T cell differentiation+++GO:0001666///response to hypoxia+++GO:0001829///trophectodermal cell differentiation+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process","adenosine deaminase","[ADA_HUMAN|Reviewed]RecName: Full=Adenosine deaminase; EC=3.5.4.4 {ECO:0000269|PubMed:16670267, ECO:0000269|PubMed:23193172, ECO:0000269|PubMed:8452534}; AltName: Full=Adenosine aminohydrolase;+++[A0A0S2Z381_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 1 {ECO:0000313|EMBL:ALQ33350.1}; SubName: Full=Adenosine deaminase, isoform CRA_c {ECO:0000313|EMBL:EAW75906.1}; Flags: Fragment;+++[A0A0S2Z3B9_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 3 {ECO:0000313|EMBL:ALQ33352.1}; Flags: Fragment;+++[A0A0S2Z3T6_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 4 {ECO:0000313|EMBL:ALQ33353.1}; Flags: Fragment;+++[F5GWI4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 2 {ECO:0000313|EMBL:ALQ33351.1};+++[F5GXW0_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000440946};+++[F5GYD4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000446464};+++[Q16073_HUMAN|Unreviewed]SubName: Full=Mutant adenosine deaminase {ECO:0000313|EMBL:AAB28742.2}; Flags: Fragment;+++[X5D767_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform A {ECO:0000313|EMBL:AHW56400.1}; Flags: Fragment;"]
[1000,"'CDH2'",7721,6358,5781,6620,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0005788///endoplasmic reticulum lumen+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005911///cell-cell junction+++GO:0016324///apical plasma membrane+++GO:0016342///catenin complex+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0045177///apical part of cell+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0005916///fascia adherens+++GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0042383///sarcolemma+++GO:0030864///cortical actin cytoskeleton+++GO:0044853///plasma membrane raft","GO:0008092///cytoskeletal protein binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding+++GO:0045294///alpha-catenin binding+++GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0060019///radial glial cell differentiation+++GO:0051146///striated muscle cell differentiation+++GO:0007416///synapse assembly+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0072659///protein localization to plasma membrane+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0034332///adherens junction organization+++GO:0048514///blood vessel morphogenesis+++GO:0043410///positive regulation of MAPK cascade+++GO:0060563///neuroepithelial cell differentiation+++GO:0021987///cerebral cortex development+++GO:0010001///glial cell differentiation+++GO:0048854///brain morphogenesis+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050770///regulation of axonogenesis+++GO:1902897///regulation of postsynaptic density protein 95 clustering+++GO:0043687///post-translational protein modification+++GO:0016477///cell migration+++GO:0097150///neuronal stem cell population maintenance+++GO:0048872///homeostasis of number of cells+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0009966///regulation of signal transduction+++GO:0098609///cell-cell adhesion+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0021537///telencephalon development+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0044267///cellular protein metabolic process","cadherin 2","[CADH2_HUMAN|Reviewed]RecName: Full=Cadherin-2; AltName: Full=CDw325; AltName: Full=Neural cadherin; Short=N-cadherin; AltName: CD_antigen=CD325; Flags: Precursor;+++[A0A024RC42_HUMAN|Unreviewed]SubName: Full=Cadherin 2, type 1, N-cadherin (Neuronal), isoform CRA_b {ECO:0000313|EMBL:EAX01241.1};+++[C9J126_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000412120}; Flags: Fragment;+++[C9J8J8_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000411360}; Flags: Fragment;+++[C9JMH2_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000414269}; Flags: Fragment;"]
[10000,"'AKT3'",763,650,783,732,"04973///Carbohydrate digestion and absorption+++04150///mTOR signaling pathway+++05211///Renal cell carcinoma+++05230///Central carbon metabolism in cancer+++05221///Acute myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++05145///Toxoplasmosis+++04910///Insulin signaling pathway+++05218///Melanoma+++05166///HTLV-I infection+++04261///Adrenergic signaling in cardiomyocytes+++05164///Influenza A+++04668///TNF signaling pathway+++05210///Colorectal cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05165///Human papillomavirus infection+++04611///Platelet activation+++04722///Neurotrophin signaling pathway+++04071///Sphingolipid signaling pathway+++04212///Longevity regulating pathway - worm+++04371///Apelin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04664///Fc epsilon RI signaling pathway+++05163///Human cytomegalovirus infection+++04024///cAMP signaling pathway+++05226///Gastric cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04550///Signaling pathways regulating pluripotency of stem cells+++04068///FoxO signaling pathway+++04062///Chemokine signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04660///T cell receptor signaling pathway+++04728///Dopaminergic synapse+++04213///Longevity regulating pathway - multiple species+++05160///Hepatitis C+++01524///Platinum drug resistance+++05222///Small cell lung cancer+++04630///Jak-STAT signaling pathway+++04510///Focal adhesion+++05200///Pathways in cancer+++04218///Cellular senescence+++04662///B cell receptor signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04917///Prolactin signaling pathway+++05225///Hepatocellular carcinoma+++05214///Glioma+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++05169///Epstein-Barr virus infection+++05213///Endometrial cancer+++04931///Insulin resistance+++04920///Adipocytokine signaling pathway+++04915///Estrogen signaling pathway+++05161///Hepatitis B+++04066///HIF-1 signaling pathway+++04625///C-type lectin receptor signaling pathway+++05231///Choline metabolism in cancer+++04014///Ras signaling pathway+++05162///Measles+++04151///PI3K-Akt signaling pathway+++04926///Relaxin signaling pathway+++04012///ErbB signaling pathway+++04922///Glucagon signaling pathway+++05224///Breast cancer+++04211///Longevity regulating pathway+++05215///Prostate cancer+++04152///AMPK signaling pathway+++04914///Progesterone-mediated oocyte maturation+++05212///Pancreatic cancer+++04022///cGMP-PKG signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05220///Chronic myeloid leukemia+++04620///Toll-like receptor signaling pathway+++04725///Cholinergic synapse+++04072///Phospholipase D signaling pathway+++04210///Apoptosis+++05152///Tuberculosis+++04140///Autophagy - animal+++05205///Proteoglycans in cancer+++05223///Non-small cell lung cancer+++04370///VEGF signaling pathway+++04919///Thyroid hormone signaling pathway+++04380///Osteoclast differentiation","H01556///Meningioma+++H01222///Cowden syndrome+++H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01909///Hypoinsulinemic hypoglycemia with hemihypertrophy (HIHGHH)+++H00420///Familial partial lipodystrophy (FPL)+++H01649///Schizophrenia+++H00027///Ovarian cancer","M00676///PI3K-Akt signaling",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0035556///intracellular signal transduction+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032008///positive regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0045766///positive regulation of angiogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0045793///positive regulation of cell size+++GO:0000002///mitochondrial genome maintenance+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0048854///brain morphogenesis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0006468///protein phosphorylation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007165///signal transduction+++GO:1905653///positive regulation of artery morphogenesis","AKT serine/threonine kinase 3","[AKT3_HUMAN|Reviewed]RecName: Full=RAC-gamma serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Protein kinase Akt-3; AltName: Full=Protein kinase B gamma; Short=PKB gamma; AltName: Full=RAC-PK-gamma; AltName: Full=STK-2;+++[F8VS91_HUMAN|Unreviewed]SubName: Full=RAC-gamma serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000447820}; Flags: Fragment;+++[Q56A86_HUMAN|Unreviewed]SubName: Full=AKT3 protein {ECO:0000313|EMBL:AAH20479.1}; Flags: Fragment;"]
[10001,"'MED6'",212.02,203.01,198,204.343333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0000151///ubiquitin ligase complex+++GO:0070847///core mediator complex+++GO:0005654///nucleoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0003712///transcription coregulator activity+++GO:0008134///transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001128///RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance+++GO:0016567///protein ubiquitination","mediator complex subunit 6","[MED6_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6; AltName: Full=Activator-recruited cofactor 33 kDa component; Short=ARC33; AltName: Full=Mediator complex subunit 6; Short=hMed6; AltName: Full=Renal carcinoma antigen NY-REN-28;+++[A0A087WYL7_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};+++[B4DTY4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|RuleBase:RU364143}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|RuleBase:RU364143};+++[G3V4A5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};"]
[10002,"'NR2E3'",0,1,0,0.333333333333333,null,"H00805///Vitreoretinal degeneration+++H02075///Enhanced S-cone syndrome+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0003707///steroid hormone receptor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0008285///negative regulation of cell proliferation+++GO:0007165///signal transduction+++GO:0060041///retina development in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0050896///response to stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007601///visual perception+++GO:0042462///eye photoreceptor cell development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045872///positive regulation of rhodopsin gene expression+++GO:0007602///phototransduction+++GO:0006367///transcription initiation from RNA polymerase II promoter","nuclear receptor subfamily 2 group E member 3","[NR2E3_HUMAN|Reviewed]RecName: Full=Photoreceptor-specific nuclear receptor; AltName: Full=Nuclear receptor subfamily 2 group E member 3; AltName: Full=Retina-specific nuclear receptor;+++[F1D8Q9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2, group E, member 3, isoform CRA_b {ECO:0000313|EMBL:EAW77877.1}; SubName: Full=Photoreceptor cell-specific nuclear receptor variant 1 {ECO:0000313|EMBL:ADZ17358.1};+++[Q8IVZ9_HUMAN|Unreviewed]SubName: Full=NR2E3 protein {ECO:0000313|EMBL:AAH41421.1}; SubName: Full=Photoreceptor-specific nuclear receptor {ECO:0000313|Ensembl:ENSP00000479254};+++[Q9UNH8_HUMAN|Unreviewed]SubName: Full=Photoreceptor-specific nuclear receptor {ECO:0000313|EMBL:AAD28302.1}; Flags: Fragment;"]
[10003,"'NAALAD2'",61,26,71,52.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0008236///serine-type peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0016805///dipeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity","GO:0006508///proteolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0042135///neurotransmitter catabolic process+++GO:0008152///metabolic process","N-acetylated alpha-linked acidic dipeptidase 2","[NALD2_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[E9PII2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000431989}; Flags: Fragment;+++[E9PJ53_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435670}; Flags: Fragment;+++[E9PJV2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000433710};+++[E9PKX5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435249};+++[J3KNJ3_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000320083};+++[L8EAF7_HUMAN|Unreviewed]SubName: Full=Alternative protein NAALAD2 {ECO:0000313|EMBL:CCQ43323.1};+++[Q4G181_HUMAN|Unreviewed]SubName: Full=NAALAD2 protein {ECO:0000313|EMBL:AAH27594.1};"]
[100037417,"'DDTL'",35.8,20.7,17.17,24.5566666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0016829///lyase activity",null,"D-dopachrome tautomerase like","[DDTL_HUMAN|Reviewed]RecName: Full=D-dopachrome decarboxylase-like protein; EC=4.1.1.-; AltName: Full=D-dopachrome tautomerase-like protein;+++[A0A0F7RPW6_HUMAN|Unreviewed]SubName: Full=D-dopachrome tautomerase 2 {ECO:0000313|EMBL:CCP37992.1};+++[B5MC82_HUMAN|Unreviewed]SubName: Full=D-dopachrome decarboxylase {ECO:0000313|Ensembl:ENSP00000384866};"]
[10004,"'NAALADL1'",22,16,28,22,{"$nulls":4},"GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004180///carboxypeptidase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity","GO:0008152///metabolic process+++GO:0006508///proteolysis","N-acetylated alpha-linked acidic dipeptidase like 1","[NALDL_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein; Short=NAALADase L; EC=3.4.17.21; AltName: Full=100 kDa ileum brush border membrane protein; Short=I100; AltName: Full=Ileal dipeptidylpeptidase;+++[C9JFW8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000349045};+++[E9PII9_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431977};+++[E9PIU1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433892}; Flags: Fragment;+++[E9PJQ1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435549}; Flags: Fragment;+++[E9PKG8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433538}; Flags: Fragment;+++[E9PKR0_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431513};+++[E9PKW7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435267}; Flags: Fragment;+++[E9PLR8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431322}; Flags: Fragment;+++[E9PRC7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434233}; Flags: Fragment;+++[H0YDS5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434225}; Flags: Fragment;+++[H0YEI8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435917}; Flags: Fragment;"]
[10005,"'ACOT8'",390,339,309,346,"00120///Primary bile acid biosynthesis+++01100///Metabolic pathways+++04146///Peroxisome",null,"M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R03974///chenodeoxycholoyl-CoA hydrolase   Chenodeoxycholate + CoA <=> Chenodeoxycholoyl-CoA + H2O+++R07296///choloyl-CoA hydrolase   Choloyl-CoA + H2O <=> Cholic acid + CoA","GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol","GO:0052815///medium-chain acyl-CoA hydrolase activity+++GO:0005102///signaling receptor binding+++GO:0052816///long-chain acyl-CoA hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0033882///choloyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0003986///acetyl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016289///CoA hydrolase activity","GO:0043649///dicarboxylic acid catabolic process+++GO:0007031///peroxisome organization+++GO:0045225///negative regulation of CD4 biosynthetic process+++GO:0016032///viral process+++GO:0006637///acyl-CoA metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0016559///peroxisome fission+++GO:0036109///alpha-linolenic acid metabolic process","acyl-CoA thioesterase 8","[ACOT8_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A thioesterase 8; Short=Acyl-CoA thioesterase 8; EC=3.1.2.27 {ECO:0000269|PubMed:15194431, ECO:0000269|PubMed:9299485}; AltName: Full=Choloyl-coenzyme A thioesterase; AltName: Full=HIV-Nef-associated acyl-CoA thioesterase; AltName: Full=PTE-2; AltName: Full=Peroxisomal acyl-coenzyme A thioester hydrolase 1; Short=PTE-1; AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase 1; AltName: Full=Thioesterase II; Short=hACTE-III; Short=hACTEIII; Short=hTE;+++[E9PIS4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000433923};+++[E9PJN0_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435581};+++[E9PMC4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000431175};+++[E9PRD4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000434216};+++[F6VBM3_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435115};+++[H0Y698_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000403862}; Flags: Fragment;+++[H7C5A7_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000419403}; Flags: Fragment;+++[Q6FHI2_HUMAN|Unreviewed]SubName: Full=PTE1 protein {ECO:0000313|EMBL:CAG46570.1};+++[Q9BR14_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000416217}; Flags: Fragment;"]
[10006,"'ABI1'",1781,1414,1764,1653,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0005783///endoplasmic reticulum+++GO:0031252///cell leading edge+++GO:0005634///nucleus+++GO:0031209///SCAR complex+++GO:0014069///postsynaptic density+++GO:0030426///growth cone+++GO:0032433///filopodium tip+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0030175///filopodium+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005856///cytoskeleton","GO:0030296///protein tyrosine kinase activator activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0017124///SH3 domain binding+++GO:0045296///cadherin binding","GO:0048813///dendrite morphogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0072673///lamellipodium morphogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0016032///viral process+++GO:0035855///megakaryocyte development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001756///somitogenesis+++GO:0008154///actin polymerization or depolymerization","abl interactor 1","[ABI1_HUMAN|Reviewed]RecName: Full=Abl interactor 1; AltName: Full=Abelson interactor 1; Short=Abi-1; AltName: Full=Abl-binding protein 4; Short=AblBP4; AltName: Full=Eps8 SH3 domain-binding protein; Short=Eps8-binding protein; AltName: Full=Nap1-binding protein; Short=Nap1BP; AltName: Full=Spectrin SH3 domain-binding protein 1; AltName: Full=e3B1;+++[A0A0A0MRT6_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000365330};+++[B6VEX3_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 41 {ECO:0000313|EMBL:ACJ12783.1};+++[B6VEX4_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000439646}; SubName: Full=Abl-interactor 1 variant 21 {ECO:0000313|EMBL:ACJ12784.1};+++[B6VEX5_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 72 {ECO:0000313|EMBL:ACJ12785.1};+++[L8EC66_HUMAN|Unreviewed]SubName: Full=Alternative protein ABI1 {ECO:0000313|EMBL:CCQ43032.1};"]
[10007,"'GNPDA1'",820,732,805,785.666666666667,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways",null,null,"R00765///D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); D-glucosamine-6-phosphate   D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia","GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0043209///myelin sheath+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0060170///ciliary membrane+++GO:0034774///secretory granule lumen","GO:0016853///isomerase activity+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0004347///glucose-6-phosphate isomerase activity+++GO:0016787///hydrolase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0048029///monosaccharide binding+++GO:0042802///identical protein binding+++GO:0004342///glucosamine-6-phosphate deaminase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0016866///intramolecular transferase activity+++GO:0008134///transcription factor binding+++GO:0004672///protein kinase activity+++GO:0004707///MAP kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding","GO:0051156///glucose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0006094///gluconeogenesis+++GO:0016310///phosphorylation+++GO:0033574///response to testosterone+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0006043///glucosamine catabolic process+++GO:0032570///response to progesterone+++GO:0035556///intracellular signal transduction+++GO:0001707///mesoderm formation+++GO:0007338///single fertilization+++GO:0016055///Wnt signaling pathway+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0035902///response to immobilization stress+++GO:0042501///serine phosphorylation of STAT protein+++GO:0010595///positive regulation of endothelial cell migration+++GO:0035994///response to muscle stretch+++GO:0061621///canonical glycolysis+++GO:0043312///neutrophil degranulation+++GO:0005975///carbohydrate metabolic process+++GO:0046777///protein autophosphorylation+++GO:0007599///hemostasis+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0010469///regulation of signaling receptor activity+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0000165///MAPK cascade+++GO:0050821///protein stabilization+++GO:0001701///in utero embryonic development+++GO:0046185///aldehyde catabolic process+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0046686///response to cadmium ion+++GO:0042593///glucose homeostasis+++GO:0019242///methylglyoxal biosynthetic process+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0043278///response to morphine+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006959///humoral immune response+++GO:0032355///response to estradiol+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010468///regulation of gene expression+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0007611///learning or memory+++GO:0006468///protein phosphorylation+++GO:0034101///erythrocyte homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006046///N-acetylglucosamine catabolic process","glucosamine-6-phosphate deaminase 1","[GNPI1_HUMAN|Reviewed]RecName: Full=Glucosamine-6-phosphate isomerase 1; EC=3.5.99.6; AltName: Full=Glucosamine-6-phosphate deaminase 1; Short=GNPDA 1; Short=GlcN6P deaminase 1; AltName: Full=Oscillin;+++[A0A0A0MTS2_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0G2JLI6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464798}; Flags: Fragment;+++[A0A0J9YX90_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488295}; Flags: Fragment;+++[A0A0J9YXH9_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488409}; Flags: Fragment;+++[A0A0J9YXM3_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488465}; Flags: Fragment;+++[A0A0J9YXP8_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYH3_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYI8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488871}; Flags: Fragment;+++[A0A2R8Y6C7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000495129};+++[A0A2R8YF08_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000496041}; Flags: Fragment;+++[D6R917_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000422173}; Flags: Fragment;+++[D6R9P4_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197};+++[D6RAY7_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RB13_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFF8_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFK5_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000426583}; Flags: Fragment;+++[K7EIL4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464797}; Flags: Fragment;+++[K7ELR7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466191}; Flags: Fragment;+++[K7ENA0_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466851}; Flags: Fragment;+++[K7EP41_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467221}; Flags: Fragment;+++[K7EPY4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467590}; Flags: Fragment;+++[K7EQ48_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[K7ERC6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468201}; Flags: Fragment;+++[K7ERK8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468298}; Flags: Fragment;"]
[10008,"'KCNE3'",30,43,51,41.3333333333333,"04974///Protein digestion and absorption","H00728///Brugada syndrome (BRS)+++H00215///Periodic paralysis",null,null,"GO:0031982///vesicle+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0008076///voltage-gated potassium channel complex+++GO:0005886///plasma membrane+++GO:0043204///perikaryon+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0032809///neuronal cell body membrane","GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005515///protein binding+++GO:0005244///voltage-gated ion channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity","GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:0006813///potassium ion transport+++GO:1905025///negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0006811///ion transport+++GO:0043266///regulation of potassium ion transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:1902260///negative regulation of delayed rectifier potassium channel activity","potassium voltage-gated channel subfamily E regulatory subunit 3","[KCNE3_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 3; AltName: Full=MinK-related peptide 2; AltName: Full=Minimum potassium ion channel-related peptide 2; AltName: Full=Potassium channel subunit beta MiRP2;+++[E9PJQ7_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000435539}; Flags: Fragment;+++[E9PJV9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000433697}; Flags: Fragment;+++[E9PN03_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000434890}; Flags: Fragment;+++[Q2N1I1_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3a {ECO:0000313|EMBL:ABB00304.1}; SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3b {ECO:0000313|EMBL:ABB00305.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000431739}; Flags: Fragment;+++[Q6IAE6_HUMAN|Unreviewed]SubName: Full=KCNE3 protein {ECO:0000313|EMBL:CAG33490.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|EMBL:ABQ01240.1}; SubName: Full=Potassium voltage-gated channel, Isk-related family, member 3 {ECO:0000313|EMBL:AAI10613.1}; SubName: Full=cDNA, FLJ92142, Homo sapiens potassium voltage-gated channel, Isk-related family,member 3 (KCNE3), mRNA {ECO:0000313|EMBL:BAG34817.1};"]
[10009,"'ZBTB33'",404,306,314,341.333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0003677///DNA binding+++GO:0008327///methyl-CpG binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035556///intracellular signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway","zinc finger and BTB domain containing 33","[KAISO_HUMAN|Reviewed]RecName: Full=Transcriptional regulator Kaiso; AltName: Full=Zinc finger and BTB domain-containing protein 33;+++[L8E7W8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZBTB33 {ECO:0000313|EMBL:CCQ43375.1};"]
[1001,"'CDH3'",8443,7790,9716,8649.66666666667,"04514///Cell adhesion molecules (CAMs)","H00785///Congenital hypotrichosis with juvenile macular dystrophy+++H00639///Ectodermal dysplasia, ectrodactyly, and macular dystrophy (EEM syndrome)",null,null,"GO:0005913///cell-cell adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0098794///postsynapse+++GO:0005802///trans-Golgi network+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0030027///lamellipodium+++GO:0016328///lateral plasma membrane+++GO:0016600///flotillin complex+++GO:0005768///endosome+++GO:0043296///apical junction complex+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane","GO:0030506///ankyrin binding+++GO:0042802///identical protein binding+++GO:0032794///GTPase activating protein binding+++GO:0045295///gamma-catenin binding+++GO:0005509///calcium ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0045296///cadherin binding+++GO:0008013///beta-catenin binding","GO:0035635///entry of bacterium into host cell+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0072659///protein localization to plasma membrane+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0009636///response to toxic substance+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0022405///hair cycle process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0051796///negative regulation of timing of catagen+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0098609///cell-cell adhesion+++GO:0071681///cellular response to indole-3-methanol+++GO:0031424///keratinization+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0010628///positive regulation of gene expression+++GO:0001895///retina homeostasis+++GO:0042060///wound healing+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0071285///cellular response to lithium ion+++GO:1902910///positive regulation of melanosome transport+++GO:0031175///neuron projection development+++GO:0007601///visual perception+++GO:0007155///cell adhesion","cadherin 3","[CADH3_HUMAN|Reviewed]RecName: Full=Cadherin-3; AltName: Full=Placental cadherin; Short=P-cadherin; Flags: Precursor;+++[B4DLF0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50795, highly similar to Cadherin-3 {ECO:0000313|EMBL:BAG59512.1};"]
[10010,"'TANK'",284,229,242,251.666666666667,"04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway",{"$nulls":3},"GO:0035631///CD40 receptor complex+++GO:0097057///TRAF2-GSTP1 complex+++GO:0005654///nucleoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0045121///membrane raft+++GO:1990604///IRE1-TRAF2-ASK1 complex+++GO:0012506///vesicle membrane+++GO:0000151///ubiquitin ligase complex+++GO:0005938///cell cortex+++GO:1990597///AIP1-IRE1 complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex","GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0019899///enzyme binding+++GO:0046625///sphingolipid binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005174///CD40 receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035800///deubiquitinase activator activity+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0031996///thioesterase binding+++GO:0008289///lipid binding","GO:0070207///protein homotrimerization+++GO:0051291///protein heterooligomerization+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:0016579///protein deubiquitination+++GO:0007165///signal transduction+++GO:0006915///apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:2000158///positive regulation of ubiquitin-specific protease activity+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016032///viral process+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0032743///positive regulation of interleukin-2 production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0065003///protein-containing complex assembly+++GO:0070534///protein K63-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0071479///cellular response to ionizing radiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0090073///positive regulation of protein homodimerization activity+++GO:0071550///death-inducing signaling complex assembly+++GO:0043507///positive regulation of JUN kinase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1901215///negative regulation of neuron death+++GO:0051865///protein autoubiquitination+++GO:0097300///programmed necrotic cell death+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0034976///response to endoplasmic reticulum stress+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0051023///regulation of immunoglobulin secretion+++GO:0071347///cellular response to interleukin-1+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0046328///regulation of JNK cascade+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0006508///proteolysis+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030163///protein catabolic process+++GO:0034622///cellular protein-containing complex assembly+++GO:0071356///cellular response to tumor necrosis factor+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0034351///negative regulation of glial cell apoptotic process","TRAF family member associated NFKB activator","[TANK_HUMAN|Reviewed]RecName: Full=TRAF family member-associated NF-kappa-B activator; AltName: Full=TRAF-interacting protein; Short=I-TRAF;+++[B1AMX7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000405860}; Flags: Fragment;+++[B1AMX8_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000406524}; Flags: Fragment;+++[B1AMY1_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000397653}; Flags: Fragment;+++[B2R7S3_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93580, highly similar to Homo sapiens TRAF family member-associated NFKB activator (TANK), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG35920.1};+++[E5KBQ3_HUMAN|Unreviewed]SubName: Full=TRAF2 {ECO:0000313|EMBL:ADQ89802.1};+++[E7EM55_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412622};+++[E7EMT6_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000392776}; Flags: Fragment;+++[E7ENY2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000411041}; Flags: Fragment;+++[E7EQA9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000385487};+++[E7ERM9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000388930};+++[E7EV32_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000398157}; Flags: Fragment;+++[E7EVA2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384492};+++[E7EW82_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384235};+++[E7EWR8_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000399934}; Flags: Fragment;+++[E9PEK1_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000410259};+++[H7BZ28_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000387439}; Flags: Fragment;+++[H7C3L4_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412556}; Flags: Fragment;+++[Q4ZG76_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAX88939.1}; Flags: Fragment;+++[Q53TI5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAY14785.1}; Flags: Fragment;+++[Q6NW12_HUMAN|Unreviewed]SubName: Full=TANK protein {ECO:0000313|EMBL:AAH67779.1};"]
[100101267,"'POM121C'",2851.9,2569.57,2917.86,2779.77666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005515///protein binding+++GO:0035804///structural constituent of egg coat+++GO:0017056///structural constituent of nuclear pore+++GO:0003676///nucleic acid binding+++GO:0008139///nuclear localization sequence binding","GO:0007339///binding of sperm to zona pellucida+++GO:0035803///egg coat formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016032///viral process+++GO:0051028///mRNA transport+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus","POM121 transmembrane nucleoporin C","[P121C_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[A1L4L9_HUMAN|Unreviewed]SubName: Full=POM121C protein {ECO:0000313|EMBL:AAI30588.1};+++[A8MY32_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000381415}; Flags: Fragment;+++[B4DDR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56876, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG56826.1};+++[B4DET5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG57196.1};+++[C9JFL1_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000410033}; Flags: Fragment;"]
[100101467,"'ZSCAN30'",203,153,189,181.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated","zinc finger and SCAN domain containing 30","[ZSC30_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 30; AltName: Full=ZNF-WYM; AltName: Full=Zinc finger protein 397 opposite strand; AltName: Full=Zinc finger protein 397OS;+++[A0A0C4DGV0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000480152};+++[A0A1W2PP20_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000491237};+++[C9JCM2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000465046};+++[K7EPB0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000467308}; Flags: Fragment;+++[K7ERA9_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000468180}; Flags: Fragment;+++[M0QZC3_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470443};+++[M0QZP2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470677}; Flags: Fragment;+++[M0R1Y0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000472179};"]
[10011,"'SRA1'",645,656,578,626.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge","GO:0003713///transcription coactivator activity+++GO:0002153///steroid receptor RNA activator RNA binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:2000273///positive regulation of signaling receptor activity+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0006351///transcription, DNA-templated+++GO:0071391///cellular response to estrogen stimulus","steroid receptor RNA activator 1","[SRA1_HUMAN|Reviewed]RecName: Full=Steroid receptor RNA activator 1; AltName: Full=Steroid receptor RNA activator protein; Short=SRAP;"]
[100113407,"'TMEM170B'",116,78.31,95,96.4366666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway","transmembrane protein 170B","[T170B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 170B;"]
[100125288,"'ZGLP1'",30,33,30,31,{"$nulls":4},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0048599///oocyte development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis","zinc finger, GATA-like protein 1","[ZGLP1_HUMAN|Reviewed]RecName: Full=GATA-type zinc finger protein 1; AltName: Full=GATA-like protein 1; Short=GLP-1;+++[B5MCP8_HUMAN|Unreviewed]SubName: Full=GATA-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000385403};"]
[100127983,"'C8orf88'",281,222,230,244.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0008190///eukaryotic initiation factor 4E binding","GO:0045947///negative regulation of translational initiation","chromosome 8 open reading frame 88","[CH088_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C8orf88;"]
[100128071,"'FAM229A'",19,31,43,31,{"$nulls":7},"family with sequence similarity 229 member A","[F229A_HUMAN|Reviewed]RecName: Full=Protein FAM229A;+++[H3BMD6_HUMAN|Unreviewed]SubName: Full=Protein FAM229A {ECO:0000313|Ensembl:ENSP00000454338}; Flags: Fragment;"]
[100128108,"'LOC100128108'",11,3,7,7,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"putative ubiquitin-conjugating enzyme E2Q2-like protein","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;+++[UB2Q2_BOVIN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_HUMAN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_MOUSE|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_RABIT|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-conjugating enzyme UBCi; AltName: Full=Ubiquitin-protein ligase Q2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100128242,"'LOC100128242'",22,17,0,13,{"$nulls":7},"uncharacterized LOC100128242","[A0A1B0GVV0_HUMAN|diamond]SubName: Full=GRAM domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000490665};+++[A0A2I3SSV7_PANTR|diamond]SubName: Full=GRAM domain containing 1B {ECO:0000313|Ensembl:ENSPTRP00000080022};+++[A0A2J8N1X4_PANTR|diamond]SubName: Full=GRAMD1B isoform 18 {ECO:0000313|EMBL:PNI65769.1};+++[A0A2J8X087_PONAB|diamond]SubName: Full=GRAMD1B isoform 17 {ECO:0000313|EMBL:PNJ75447.1};+++[A0A2R9B6E3_PANPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000024636};"]
[100128553,"'CTAGE4'",57.44,57.35,52.45,55.7466666666667,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0042954///lipoprotein transporter activity","GO:0042953///lipoprotein transport+++GO:0008150///biological_process+++GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion","CTAGE family member 4","[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[A0A2R8Y569_HUMAN|Unreviewed]SubName: Full=cTAGE family member 4 {ECO:0000313|Ensembl:ENSP00000494570};"]
[100128569,"'C19orf71'",1,0,0,0.333333333333333,{"$nulls":7},"chromosome 19 open reading frame 71","[CS071_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf71;"]
[100128731,"'OST4'",1338,1490,1284,1370.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0015631///tubulin binding+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding","GO:0018279///protein N-linked glycosylation via asparagine+++GO:0006486///protein glycosylation","oligosaccharyltransferase complex subunit 4, non-catalytic","[OST4_HUMAN|Reviewed]RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4;"]
[100128927,"'ZBTB42'",84,85,74,81,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0007517///muscle organ development+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 42","[ZBT42_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 42;"]
[100129250,"'SMIM27'",37,36,37,36.6666666666667,"05016///Huntington's disease+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++05012///Parkinson's disease+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)",null,"M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly","small integral membrane protein 27","[SIM27_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 27 {ECO:0000305}; AltName: Full=TOPORS antisense RNA 1 {ECO:0000305};+++[A0A1B0GV65_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490387};+++[A0A1B0GW09_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490727}; Flags: Fragment;+++[A0A1W2PRY6_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000492552}; Flags: Fragment;+++[A0A286YEC1_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000414891};+++[A0A2R8Y3B0_HUMAN|Unreviewed]SubName: Full=HCG1811779, isoform CRA_a {ECO:0000313|EMBL:EAW58544.1}; SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000493510};"]
[100129361,"'SMIM10L1'",606,547,519,557.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"small integral membrane protein 10 like 1","[SIML1_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 1 {ECO:0000305};"]
[100129396,"'FAM106CP'",0,0,3.99,1.33,{"$nulls":7},"family with sequence similarity 106 member C, pseudogene","[F106C_HUMAN|Reviewed]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;"]
[100129480,"'MKRN2OS'",5.9,1.43,10,5.77666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"MKRN2 opposite strand","[MKROS_HUMAN|Reviewed]RecName: Full=MKRN2 opposite strand protein; AltName: Full=MKRN2 antisense RNA 1; AltName: Full=MKRN2 antisense gene protein 1;+++[H3BSJ0_HUMAN|Unreviewed]SubName: Full=MKRN2 opposite strand protein {ECO:0000313|Ensembl:ENSP00000456723};"]
[100129484,"'LOC100129484'",25,17,18,20,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100129484","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100129543,"'ZNF730'",12,9,10,10.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 730","[ZN730_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 730;+++[M0QYG2_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469805}; Flags: Fragment;+++[M0QYI4_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469853};"]
[100129583,"'FAM47E'",4.14,8.78,6.82,6.58,{"$nulls":4},"GO:0005737///cytoplasm","GO:0003674///molecular_function","GO:0008150///biological_process","family with sequence similarity 47 member E","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[A0A1B0GTQ8_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000489801};+++[A0A1B0GUL4_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000490159};+++[D6RBT2_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000422559}; Flags: Fragment;+++[U3KQR7_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000476166}; Flags: Fragment;"]
[100129792,"'CCDC152'",38,20,22,26.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031089///platelet dense granule lumen+++GO:0005576///extracellular region","GO:0008430///selenium binding","GO:0019953///sexual reproduction+++GO:0001887///selenium compound metabolic process+++GO:0007626///locomotory behavior+++GO:0002576///platelet degranulation+++GO:0009791///post-embryonic development+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0040008///regulation of growth","coiled-coil domain containing 152","[CC152_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 152;+++[A0A024R043_HUMAN|Unreviewed]SubName: Full=HCG2006161, isoform CRA_a {ECO:0000313|EMBL:EAW56025.1};+++[L0R835_HUMAN|Unreviewed]SubName: Full=Alternative protein CCDC152 {ECO:0000313|EMBL:CCO13701.1};"]
[100129842,"'ZNF737'",161,83,141.93,128.643333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 737","[ZN737_HUMAN|Reviewed]RecName: Full=Zinc finger protein 737; AltName: Full=Zinc finger protein 102;+++[M0QZS4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000470737};+++[M0R1D1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471784}; Flags: Fragment;+++[M0R1M3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471973};+++[M0R1M8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471995}; Flags: Fragment;"]
[100129924,"'TMEM269'",2,1,3,2,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 269","[TM269_HUMAN|Reviewed]RecName: Full=Transmembrane protein 269 {ECO:0000312|HGNC:HGNC:52381};+++[A0A1B0GUR4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 269 {ECO:0000313|Ensembl:ENSP00000490213};"]
[100129940,"'LOC100129940'",4,5,3,4,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030686///90S preribosome","GO:0043236///laminin binding+++GO:0043022///ribosome binding+++GO:0003723///RNA binding+++GO:0005055///laminin receptor activity+++GO:0001618///virus receptor activity+++GO:0003735///structural constituent of ribosome","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000028///ribosomal small subunit assembly+++GO:0007155///cell adhesion+++GO:0006412///translation+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006413///translational initiation+++GO:0000461///endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006407///rRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","uncharacterized LOC100129940","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RSSA_BOVIN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Protein C10;+++[RSSA_CHLAE|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_HUMAN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Colon carcinoma laminin-binding protein; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Multidrug resistance-associated protein MGr1-Ag; AltName: Full=NEM/1CHD4; AltName: Full=Small ribosomal subunit protein uS2 {ECO:0000303|PubMed:24524803};+++[RSSA_PIG|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_SHEEP|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10013,"'HDAC6'",889,1005,1023,972.333333333333,"05034///Alcoholism+++05203///Viral carcinogenesis+++05165///Human papillomavirus infection",{"$nulls":3},"GO:0016235///aggresome+++GO:0005874///microtubule+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm+++GO:0016234///inclusion body+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0030286///dynein complex+++GO:0005654///nucleoplasm+++GO:0005771///multivesicular body+++GO:0031252///cell leading edge+++GO:0005875///microtubule associated complex+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005881///cytoplasmic microtubule+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005901///caveola+++GO:0044297///cell body+++GO:0043204///perikaryon+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0008013///beta-catenin binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0048156///tau protein binding+++GO:0043130///ubiquitin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004407///histone deacetylase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0070840///dynein complex binding+++GO:0003779///actin binding+++GO:0042903///tubulin deacetylase activity+++GO:0051787///misfolded protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0051879///Hsp90 protein binding+++GO:0042826///histone deacetylase binding+++GO:0048487///beta-tubulin binding+++GO:0008017///microtubule binding+++GO:0043014///alpha-tubulin binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)","GO:0006886///intracellular protein transport+++GO:0031647///regulation of protein stability+++GO:0060997///dendritic spine morphogenesis+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0048668///collateral sprouting+++GO:0051788///response to misfolded protein+++GO:0070848///response to growth factor+++GO:0032984///protein-containing complex disassembly+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0009967///positive regulation of signal transduction+++GO:0000209///protein polyubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0035967///cellular response to topologically incorrect protein+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0051646///mitochondrion localization+++GO:0060271///cilium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0032461///positive regulation of protein oligomerization+++GO:0045861///negative regulation of proteolysis+++GO:0045598///regulation of fat cell differentiation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0070846///Hsp90 deacetylation+++GO:0009636///response to toxic substance+++GO:0006325///chromatin organization+++GO:0032418///lysosome localization+++GO:0010033///response to organic substance+++GO:0010727///negative regulation of hydrogen peroxide metabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016241///regulation of macroautophagy+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006914///autophagy+++GO:0043242///negative regulation of protein complex disassembly+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:0090042///tubulin deacetylation+++GO:0010506///regulation of autophagy+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0060632///regulation of microtubule-based movement+++GO:0006476///protein deacetylation+++GO:0070201///regulation of establishment of protein localization+++GO:0070842///aggresome assembly+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070845///polyubiquitinated misfolded protein transport+++GO:0010469///regulation of signaling receptor activity+++GO:0070932///histone H3 deacetylation+++GO:0016575///histone deacetylation+++GO:0010634///positive regulation of epithelial cell migration+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0060765///regulation of androgen receptor signaling pathway","histone deacetylase 6","[HDAC6_HUMAN|Reviewed]RecName: Full=Histone deacetylase 6; Short=HD6; EC=3.5.1.98;+++[A0A024QZ26_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8Y4G2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494007}; Flags: Fragment;+++[A0A2R8Y559_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494293}; Flags: Fragment;+++[A0A2R8Y5Z4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495151};+++[A0A2R8Y6Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495932}; Flags: Fragment;+++[A0A2R8Y758_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000496032}; Flags: Fragment;+++[A0A2R8YCS4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000493921}; Flags: Fragment;+++[A0A2R8YD35_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494230}; Flags: Fragment;+++[A0A2R8YDE6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8YGC5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495872}; Flags: Fragment;+++[A6NDI8_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000365831}; Flags: Fragment;+++[B4DZH6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[C9J172_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000392815}; Flags: Fragment;+++[C9JEF4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000403370}; Flags: Fragment;+++[E7EP63_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402751}; Flags: Fragment;+++[E7EPS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402189}; Flags: Fragment;+++[E7ER52_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000394377}; Flags: Fragment;+++[H7C0Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000397697}; Flags: Fragment;+++[Q9BRX7_HUMAN|Unreviewed]SubName: Full=HDAC6 protein {ECO:0000313|EMBL:AAH05872.1}; SubName: Full=Histone deacetylase 6 {ECO:0000313|EMBL:AAP35295.1, ECO:0000313|Ensembl:ENSP00000393916};+++[Q9NSW6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};"]
[100130086,"'HSFX2'",21,11,0,10.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding","GO:0006351///transcription, DNA-templated","heat shock transcription factor family, X-linked 2","[HSFX1_HUMAN|Reviewed]RecName: Full=Heat shock transcription factor, X-linked;+++[A0A140VK21_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 21 {ECO:0000313|EMBL:AEE61158.1};"]
[100130311,"'C17orf107'",248,268,259,258.333333333333,"04080///Neuroactive ligand-receptor interaction","H00770///Congenital myasthenic syndrome",{"$nulls":5},"chromosome 17 open reading frame 107","[CQ107_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf107;+++[E5RJ01_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf107 {ECO:0000313|Ensembl:ENSP00000429241};"]
[100130357,"'LOC100130357'",3,3,3,3,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","uncharacterized LOC100130357","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RABX5_HUMAN|diamond]RecName: Full=Rab5 GDP/GTP exchange factor; AltName: Full=RAP1; AltName: Full=Rabaptin-5-associated exchange factor for Rab5; AltName: Full=Rabex-5;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[100130361,"'CXorf49'",1,0.5,1.5,1,{"$nulls":7},"chromosome X open reading frame 49","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100130370,"'LOC100130370'",88,85,71,81.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100130370","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100130451,"'LOC100130451'",2,1,2,1.66666666666667,{"$nulls":7},"uncharacterized LOC100130451","[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[100130519,"'TMEM221'",44,24,29,32.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 221","[TM221_HUMAN|Reviewed]RecName: Full=Transmembrane protein 221;"]
[100130705,"'ATP6V1FNB'",25,26,27,26,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"ATP6V1F neighbor","[VAFNB_HUMAN|Reviewed]RecName: Full=Protein ATP6V1FNB {ECO:0000305}; AltName: Full=ATP6V1F neighbor gene protein {ECO:0000305};"]
[100130733,"'LRRC70'",3,0,3,2,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005149///interleukin-1 receptor binding","GO:0002237///response to molecule of bacterial origin+++GO:0007409///axonogenesis+++GO:0002224///toll-like receptor signaling pathway","leucine rich repeat containing 70","[LRR70_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 70; AltName: Full=Synleurin; Flags: Precursor;+++[D6RD14_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 70 {ECO:0000313|Ensembl:ENSP00000427117};"]
[100130771,"'EFCAB10'",3,4,3,3.33333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0010494///cytoplasmic stress granule+++GO:0005576///extracellular region+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0070939///Dsl1/NZR complex+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0005509///calcium ion binding","GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0006397///mRNA processing+++GO:0015031///protein transport+++GO:0006351///transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0051781///positive regulation of cell division+++GO:1902504///regulation of signal transduction involved in mitotic G2 DNA damage checkpoint+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007049///cell cycle+++GO:0006355///regulation of transcription, DNA-templated","EF-hand calcium binding domain 10","[EFC10_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 10;+++[A0A2R8Y6P2_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000495682};+++[A0A2R8YDC4_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000494437};+++[C9J654_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000418425};+++[J3KR48_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417484}; SubName: Full=HCG1779729, isoform CRA_a {ECO:0000313|EMBL:EAW83368.1};+++[J3KR52_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417841};"]
[100130827,"'SBK3'",0,1,0,0.333333333333333,{"$nulls":5},"GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","SH3 domain binding kinase family member 3","[SBK3_HUMAN|Reviewed]RecName: Full=Uncharacterized serine/threonine-protein kinase SBK3; EC=2.7.11.1; AltName: Full=SH3-binding domain kinase family member 3; AltName: Full=Sugen kinase 110;+++[K7EP79_HUMAN|Unreviewed]SubName: Full=Uncharacterized serine/threonine-protein kinase SBK3 {ECO:0000313|Ensembl:ENSP00000467263}; Flags: Fragment;"]
[100130880,"'LOC100130880'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC100130880"]
[100130890,"'TSTD3'",81,69,81.01,77.0033333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016592///mediator complex+++GO:0005829///cytosol+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0070911///global genome nucleotide-excision repair+++GO:0016579///protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1901409///positive regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:0006281///DNA repair+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II","thiosulfate sulfurtransferase like domain containing 3","[TSTD3_HUMAN|Reviewed]RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3; AltName: Full=Rhodanese domain-containing protein 3;+++[A0A1B0GUB9_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000490043};"]
[100130933,"'SMIM6'",3,2,5,3.33333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0016020///membrane+++GO:0071953///elastic fiber+++GO:0062023///collagen-containing extracellular matrix+++GO:0016021///integral component of membrane","GO:0050840///extracellular matrix binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0005515///protein binding+++GO:0005201///extracellular matrix structural constituent","GO:0007519///skeletal muscle tissue development+++GO:0043149///stress fiber assembly+++GO:0008283///cell proliferation+++GO:0003180///aortic valve morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0008015///blood circulation+++GO:0009887///animal organ morphogenesis+++GO:0030833///regulation of actin filament polymerization+++GO:0007585///respiratory gaseous exchange+++GO:0030198///extracellular matrix organization","small integral membrane protein 6","[SMIM6_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 6;+++[A7L3I8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:ABS29265.1};+++[D3DXF3_HUMAN|Unreviewed]SubName: Full=Elastin (Supravalvular aortic stenosis, Williams-Beuren syndrome), isoform CRA_b {ECO:0000313|EMBL:EAW69630.1};+++[E7EN51_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000403961}; Flags: Fragment;+++[E7ENW7_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000411092}; Flags: Fragment;+++[E7EP82_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000389206}; Flags: Fragment;+++[E7EQH8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000394549}; Flags: Fragment;+++[E7ETP7_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000406949}; Flags: Fragment;+++[E7EWS8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000399499}; Flags: Fragment;+++[E9PGX4_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000404138};+++[H7C3K0_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000412262}; Flags: Fragment;+++[Q9UME9_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:AAC99789.1}; Flags: Fragment;+++[Q9UMK5_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:AAA52379.1}; Flags: Fragment;"]
[100130958,"'SYCE1L'",25,37,21.15,27.7166666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04138///Autophagy - yeast",{"$nulls":3},"GO:0000795///synaptonemal complex+++GO:0045111///intermediate filament cytoskeleton",null,"GO:0051321///meiotic cell cycle+++GO:0070193///synaptonemal complex organization+++GO:0007130///synaptonemal complex assembly","synaptonemal complex central element protein 1 like","[SYC1L_HUMAN|Reviewed]RecName: Full=Synaptonemal complex central element protein 1-like; AltName: Full=Meiosis-related protein;+++[H3BME6_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex central element protein 1-like {ECO:0000313|Ensembl:ENSP00000454349}; Flags: Fragment;"]
[100130967,"'C6orf99'",10,12,22,14.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"chromosome 6 open reading frame 99","[CF099_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C6orf99;"]
[100131017,"'ZNF316'",570,624,693,629,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 316","[ZN316_HUMAN|Reviewed]RecName: Full=Zinc finger protein 316;+++[A0A087WZ61_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 316 {ECO:0000313|Ensembl:ENSP00000482395}; Flags: Fragment;"]
[100131187,"'TSTD1'",148,175,141,154.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005615///extracellular space+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005739///mitochondrion","GO:0008097///5S rRNA binding+++GO:0004792///thiosulfate sulfurtransferase activity+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0050337///thiosulfate-thiol sulfurtransferase activity","GO:0051029///rRNA transport+++GO:0030855///epithelial cell differentiation+++GO:0070221///sulfide oxidation, using sulfide:quinone oxidoreductase+++GO:0035928///rRNA import into mitochondrion+++GO:0000098///sulfur amino acid catabolic process+++GO:0009440///cyanate catabolic process","thiosulfate sulfurtransferase like domain containing 1","[TSTD1_HUMAN|Reviewed]RecName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000303|PubMed:24981631}; Short=TST {ECO:0000303|PubMed:24981631}; EC=2.8.1.- {ECO:0000269|PubMed:24981631};+++[B1AH48_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase {ECO:0000313|Ensembl:ENSP00000400764}; Flags: Fragment;+++[R4GNF9_HUMAN|Unreviewed]SubName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000313|Ensembl:ENSP00000473633};"]
[100131211,"'NEMP2'",10,13,11,11.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005635///nuclear envelope","GO:0003964///RNA-directed DNA polymerase activity",null,"nuclear envelope integral membrane protein 2","[NEMP2_HUMAN|Reviewed]RecName: Full=Nuclear envelope integral membrane protein 2; Flags: Precursor;+++[C9J4F2_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000410306}; Flags: Fragment;+++[F8VWJ7_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000340087};+++[H7C232_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000403867}; Flags: Fragment;"]
[100131244,"'ANKRD63'",10,3,11,8,{"$nulls":7},"ankyrin repeat domain 63","[ANR63_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 63 {ECO:0000312|HGNC:HGNC:40027};"]
[100131378,"'C11orf91'",0,0,2,0.666666666666667,{"$nulls":7},"chromosome 11 open reading frame 91","[CK091_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf91;+++[H0YDE1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf91 {ECO:0000313|Ensembl:ENSP00000433460}; Flags: Fragment;"]
[100131755,"'ARMCX4'",102,69,75,82,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0016018///cyclosporin A binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0046790///virion binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0051082///unfolded protein binding","GO:0048469///cell maturation+++GO:0071226///cellular response to molecule of fungal origin+++GO:0035556///intracellular signal transduction+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0019061///uncoating of virus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0098761///cellular response to interleukin-7+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0034389///lipid droplet organization+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0002721///regulation of B cell cytokine production+++GO:0019076///viral release from host cell+++GO:0006351///transcription, DNA-templated+++GO:0045579///positive regulation of B cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0002553///histamine secretion by mast cell+++GO:0097190///apoptotic signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0006310///DNA recombination+++GO:0075713///establishment of integrated proviral latency+++GO:0045087///innate immune response+++GO:0002344///B cell affinity maturation+++GO:0050853///B cell receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0030260///entry into host cell+++GO:0019722///calcium-mediated signaling+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0002250///adaptive immune response+++GO:0034614///cellular response to reactive oxygen species+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0030889///negative regulation of B cell proliferation+++GO:0050900///leukocyte migration+++GO:0019058///viral life cycle+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0007498///mesoderm development+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0019068///virion assembly+++GO:0042113///B cell activation+++GO:0045069///regulation of viral genome replication+++GO:0002902///regulation of B cell apoptotic process+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0001818///negative regulation of cytokine production+++GO:0006468///protein phosphorylation+++GO:0032197///transposition, RNA-mediated","armadillo repeat containing X-linked 4","[ARMX4_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 4;+++[A0A024RCH4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 4, isoform CRA_b {ECO:0000313|EMBL:EAX02871.1};+++[D6RBS8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000422573};+++[F8W8Y7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000404304};+++[L8EAW9_HUMAN|Unreviewed]SubName: Full=Alternative protein ARMCX4 {ECO:0000313|EMBL:CCQ43981.1};"]
[100131801,"'PET100'",208,188,174,190,"03040///Spliceosome","H01368///Cytochrome c oxidase (COX) deficiency","M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0051082///unfolded protein binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","PET100 homolog","[PT100_HUMAN|Reviewed]RecName: Full=Protein PET100 homolog, mitochondrial; Flags: Precursor;+++[A0A0A0MSK2_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000392303};+++[M0QZ55_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470314}; Flags: Fragment;+++[M0R022_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470935};"]
[100131827,"'ZNF717'",32,42,36,36.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 717","[ZN717_HUMAN|Reviewed]RecName: Full=Zinc finger protein 717; AltName: Full=Krueppel-like factor X17;+++[C9J5W8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000417902};+++[C9J8I7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000418187}; Flags: Fragment;+++[C9JVC3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000419377};+++[E5RKB3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000420241}; Flags: Fragment;"]
[100131897,"'INSYN2B'",44,23,34,33.6666666666667,"04062///Chemokine signaling pathway+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0035580///specific granule lumen+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0042608///T cell receptor binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0050766///positive regulation of phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0001766///membrane raft polarization+++GO:0045059///positive thymic T cell selection+++GO:0044351///macropinocytosis+++GO:0045060///negative thymic T cell selection+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0006935///chemotaxis+++GO:0050690///regulation of defense response to virus by virus+++GO:0001771///immunological synapse formation+++GO:0007264///small GTPase mediated signal transduction+++GO:0001768///establishment of T cell polarity+++GO:0046633///alpha-beta T cell proliferation","inhibitory synaptic factor family member 2B","[INY2B_HUMAN|Reviewed]RecName: Full=Protein INSYN2B {ECO:0000305}; AltName: Full=Inhibitory synaptic factor family member 2B {ECO:0000312|HGNC:HGNC:37271};"]
[100132074,"'FOXO6'",219,306,241,255.333333333333,"04068///FoxO signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0042593///glucose homeostasis+++GO:0008286///insulin receptor signaling pathway+++GO:0007613///memory+++GO:0060999///positive regulation of dendritic spine development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","forkhead box O6","[FOXO6_HUMAN|Reviewed]RecName: Full=Forkhead box protein O6;+++[A0A1X9RU27_HUMAN|Unreviewed]SubName: Full=Forkhead box protein O6 {ECO:0000313|EMBL:ARQ84049.1};"]
[100132247,"'NPIPB5'",2023.15,2218.09,2933.66,2391.63333333333,"00650///Butanoate metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++01100///Metabolic pathways",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane",null,null,"nuclear pore complex interacting protein family member B5","[NPIB5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B5;+++[B4E0Y1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61599 {ECO:0000313|EMBL:BAG64593.1};+++[E5RHP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000456511}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000429523}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000428548}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449726};+++[E7EUG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000392155};+++[E9PKP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000431553}; Flags: Fragment;+++[F5GWQ4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000457242}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000442776}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441759}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449771};+++[F5GXZ6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000440137}; Flags: Fragment;+++[F5GYP3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441303}; Flags: Fragment;+++[F5GZP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000444299}; Flags: Fragment;+++[F5H6Y6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442935}; Flags: Fragment;+++[F6SDX0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000445388}; Flags: Fragment;+++[H0YIL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000449628}; Flags: Fragment;+++[U3KRG3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442912}; Flags: Fragment;"]
[100132406,"'NBPF10'",514.63,328.3,521.87,454.933333333333,"01522///Endocrine resistance+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++04140///Autophagy - animal+++05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation+++04137///Mitophagy - animal+++05224///Breast cancer","H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0003723///RNA binding","GO:0007275///multicellular organism development+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway","NBPF member 10","[NBPFA_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 10;+++[A0A075B762_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000463957};+++[A0A087WVC7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000479344};+++[A0A087WVG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000479415};+++[A0A087WYQ9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482016};+++[A0A087WZE1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482587};+++[A0A087X0Y3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000483736};+++[A2BH96_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 10 {ECO:0000313|EMBL:CAM23768.1};+++[I0CMK7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFH78588.1}; Flags: Fragment;+++[I1VE12_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41822.1}; Flags: Fragment;+++[I1VE13_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41823.1}; Flags: Fragment;+++[I1VE14_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41824.1}; Flags: Fragment;+++[L8E7E2_HUMAN|Unreviewed]SubName: Full=Alternative protein NBPF9 {ECO:0000313|EMBL:CCQ43049.1};+++[Q5TB04_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 9 {ECO:0000313|EMBL:CAI22821.1}; Flags: Fragment;"]
[100132463,"'CLDN24'",1,0,0,0.333333333333333,"04514///Cell adhesion molecules (CAMs)+++05160///Hepatitis C+++04530///Tight junction+++04670///Leukocyte transendothelial migration","H00742///Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome+++H01210///Hypomagnesemia+++H00605///Deafness, autosomal recessive+++H01439///Williams-Beuren syndrome",null,null,"GO:0005923///bicellular tight junction+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction","GO:0005198///structural molecule activity",null,"claudin 24","[CLD24_HUMAN|Reviewed]RecName: Full=Putative claudin-24 {ECO:0000305}; AltName: Full=Claudin-21 {ECO:0000312|HGNC:HGNC:37200};+++[D6RBY1_HUMAN|Unreviewed]RecName: Full=Claudin {ECO:0000256|RuleBase:RU060637};"]
[100132565,"'GOLGA8F'",1.01,0,0,0.336666666666667,"04120///Ubiquitin mediated proteolysis","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005794///Golgi apparatus","GO:0004842///ubiquitin-protein transferase activity+++GO:0032183///SUMO binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006886///intracellular protein transport+++GO:0007283///spermatogenesis+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0016567///protein ubiquitination","golgin A8 family member F","[A0A0G2JP71_HUMAN|Unreviewed]SubName: Full=Putative golgin subfamily A member 8F/8G {ECO:0000313|Ensembl:ENSP00000483042};+++[A0A0G2JPF6_HUMAN|Unreviewed]SubName: Full=Putative golgin subfamily A member 8F/8G {ECO:0000313|Ensembl:ENSP00000483530};"]
[100132874,"'LOC100132874'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC100132874","[RRBP1_MOUSE|diamond]RecName: Full=Ribosome-binding protein 1; AltName: Full=Ribosome receptor protein; Short=RRp; Short=mRRp;+++[SRFB1_XENTR|diamond]RecName: Full=Serum response factor-binding protein 1; AltName: Full=SRF-dependent transcription regulation-associated protein;"]
[100132911,"'DPH3P1'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046872///metal ion binding","GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0002098///tRNA wobble uridine modification","diphthamide biosynthesis 3 pseudogene 1","[DPH3B_HUMAN|Reviewed]RecName: Full=Putative DPH3 homolog B; AltName: Full=CSL-type zinc finger-containing protein 1;"]
[100132994,"'CXorf49B'",1,0.5,1.5,1,{"$nulls":7},"chromosome X open reading frame 49B","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100133093,"'FAM25G'",1,0,0,0.333333333333333,{"$nulls":7},"family with sequence similarity 25 member G","[FM25A_HUMAN|Reviewed]RecName: Full=Protein FAM25A {ECO:0000305};+++[FM25C_HUMAN|Reviewed]RecName: Full=Protein FAM25C {ECO:0000305};+++[FM25G_HUMAN|Reviewed]RecName: Full=Protein FAM25G {ECO:0000305};+++[B7ZW47_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 25, member C {ECO:0000313|EMBL:AAI71871.1};"]
[100133204,"'C9orf147'",4,3,2,3,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0016020///membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0051213///dioxygenase activity","GO:0010468///regulation of gene expression","chromosome 9 open reading frame 147","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[HSDL2_BOVIN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_HUMAN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-; AltName: Full=Short chain dehydrogenase/reductase family 13C member 1;+++[HSDL2_PONAB|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENLA|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENTR|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100133220,"'GOLGA6L3'",7.57,2.12,11.58,7.09,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"golgin A6 family-like 3","[GG6L3_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 3;"]
[100133251,"'PRR23D2'",2,0,1.96,1.32,{"$nulls":7},"proline rich 23 domain containing 2","[P23D1_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D1;+++[P23D2_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D2;"]
[100133301,"'100133301'",4,7,3,4.66666666666667,{"$nulls":8},"[F231A_HUMAN|diamond]RecName: Full=Putative protein FAM231AP {ECO:0000305};+++[F231B_HUMAN|diamond]RecName: Full=Putative protein FAM231BP;+++[F231C_HUMAN|diamond]RecName: Full=Protein FAM231C;+++[F231D_HUMAN|diamond]RecName: Full=Protein FAM231D;+++[F231L_HUMAN|diamond]RecName: Full=FAM231A/C-like protein LOC102723383;"]
[100133941,"'CD24'",3246,2790,3019,3018.33333333333,"04640///Hematopoietic cell lineage",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0045121///membrane raft+++GO:0009986///cell surface+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030296///protein tyrosine kinase activator activity","GO:0032597///B cell receptor transport into membrane raft+++GO:0032913///negative regulation of transforming growth factor beta3 production+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0030856///regulation of epithelial cell differentiation+++GO:0045730///respiratory burst+++GO:0043406///positive regulation of MAP kinase activity+++GO:0016055///Wnt signaling pathway+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:2000768///positive regulation of nephron tubule epithelial cell differentiation+++GO:0001775///cell activation+++GO:0042632///cholesterol homeostasis+++GO:0002237///response to molecule of bacterial origin+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072139///glomerular parietal epithelial cell differentiation+++GO:0001666///response to hypoxia+++GO:0042325///regulation of phosphorylation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0032600///chemokine receptor transport out of membrane raft+++GO:0043408///regulation of MAPK cascade+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0031295///T cell costimulation+++GO:0043627///response to estrogen+++GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0098609///cell-cell adhesion","CD24 molecule","[CD24_HUMAN|Reviewed]RecName: Full=Signal transducer CD24; AltName: Full=Small cell lung carcinoma cluster 4 antigen; AltName: CD_antigen=CD24; Flags: Precursor;+++[A0A087WU21_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478302};+++[A0A087WU87_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478460}; Flags: Fragment;+++[A0A087WW33_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000479895}; Flags: Fragment;"]
[100134934,"'TEN1'",151,191,167,169.666666666667,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0005634///nucleus+++GO:0000781///chromosome, telomeric region+++GO:1990879///CST complex+++GO:0005694///chromosome","GO:0042162///telomeric DNA binding+++GO:0005515///protein binding+++GO:0010521///telomerase inhibitor activity+++GO:0003697///single-stranded DNA binding+++GO:0003677///DNA binding","GO:0016233///telomere capping+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0051974///negative regulation of telomerase activity","TEN1, CST complex subunit","[TEN1L_HUMAN|Reviewed]RecName: Full=CST complex subunit TEN1; AltName: Full=Protein telomeric pathways with STN1 homolog; AltName: Full=Telomere length regulation protein TEN1 homolog;+++[D3U720_HUMAN|Unreviewed]SubName: Full=Telomeric pathways in association with Stn1 number 1 {ECO:0000313|EMBL:ACY71128.1};+++[K7EIL0_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000464792}; Flags: Fragment;+++[K7EJS2_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465299}; Flags: Fragment;+++[K7EL09_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465866};"]
[100134938,"'UPK3BL1'",246.66,372.27,314.98,311.303333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"uroplakin 3B like 1","[UPK3L_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 1 {ECO:0000312|HGNC:HGNC:37278}; Flags: Precursor;+++[UPKL2_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 2 {ECO:0000305}; Flags: Precursor;"]
[100137047,"'JMJD7'",104.01,89.91,99.8,97.9066666666667,{"$nulls":5},"GO:0005515///protein binding",null,"jumonji domain containing 7","[JMJD7_HUMAN|Reviewed]RecName: Full=JmjC domain-containing protein 7; AltName: Full=Jumonji domain-containing protein 7;+++[B5MC20_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000384174};+++[C9K0I3_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000399600}; Flags: Fragment;"]
[100137049,"'PLA2G4B'",0,0,31.66,10.5533333333333,"04726///Serotonergic synapse+++04611///Platelet activation+++04913///Ovarian steroidogenesis+++04730///Long-term depression+++04921///Oxytocin signaling pathway+++04072///Phospholipase D signaling pathway+++00564///Glycerophospholipid metabolism+++04750///Inflammatory mediator regulation of TRP channels+++00591///Linoleic acid metabolism+++00590///Arachidonic acid metabolism+++04014///Ras signaling pathway+++04217///Necroptosis+++01110///Biosynthesis of secondary metabolites+++00592///alpha-Linolenic acid metabolism+++01100///Metabolic pathways+++04724///Glutamatergic synapse+++00565///Ether lipid metabolism+++04010///MAPK signaling pathway+++04370///VEGF signaling pathway+++04270///Vascular smooth muscle contraction+++04912///GnRH signaling pathway+++05231///Choline metabolism in cancer+++04664///Fc epsilon RI signaling pathway",null,null,"R01315///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid+++R01317///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate+++R07379///plasmenylethanolamine 2-acylhydrolase   O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate+++R07064///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate+++R07387///plasmanylcholine 2-acylhydrolase   1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate+++R02053///phosphatidylethanolamine 2-acylhydrolase   Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid+++R07859///Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid","GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031966///mitochondrial membrane+++GO:0031901///early endosome membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm","GO:0008970///phospholipase A1 activity+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0004623///phospholipase A2 activity+++GO:0004622///lysophospholipase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding+++GO:0004620///phospholipase activity","GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0007567///parturition+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0046475///glycerophospholipid catabolic process+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0019369///arachidonic acid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0009395///phospholipid catabolic process+++GO:0019722///calcium-mediated signaling+++GO:0006629///lipid metabolic process+++GO:0006954///inflammatory response+++GO:0016042///lipid catabolic process+++GO:0006654///phosphatidic acid biosynthetic process","phospholipase A2 group IVB","[PA24B_HUMAN|Reviewed]RecName: Full=Cytosolic phospholipase A2 beta; Short=cPLA2-beta; EC=3.1.1.4; AltName: Full=Phospholipase A2 group IVB;+++[H3BSX5_HUMAN|Unreviewed]SubName: Full=Cytosolic phospholipase A2 beta {ECO:0000313|Ensembl:ENSP00000456919}; Flags: Fragment;"]
[10014,"'HDAC5'",1390,1415,1438,1414.33333333333,"04371///Apelin signaling pathway+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05034///Alcoholism+++05203///Viral carcinogenesis","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0005829///cytosol+++GO:0000118///histone deacetylase complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0008134///transcription factor binding+++GO:0003682///chromatin binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0070491///repressing transcription factor binding+++GO:0005515///protein binding+++GO:0005080///protein kinase C binding+++GO:0033558///protein deacetylase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0030183///B cell differentiation+++GO:0010830///regulation of myotube differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006954///inflammatory response+++GO:0042113///B cell activation+++GO:0014823///response to activity+++GO:0010832///negative regulation of myotube differentiation+++GO:0042493///response to drug+++GO:0043393///regulation of protein binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042220///response to cocaine+++GO:0040029///regulation of gene expression, epigenetic+++GO:0030182///neuron differentiation+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0006338///chromatin remodeling+++GO:0070932///histone H3 deacetylation+++GO:0006476///protein deacetylation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006325///chromatin organization+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0006342///chromatin silencing+++GO:0016575///histone deacetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032869///cellular response to insulin stimulus","histone deacetylase 5","[HDAC5_HUMAN|Reviewed]RecName: Full=Histone deacetylase 5; Short=HD5; EC=3.5.1.98; AltName: Full=Antigen NY-CO-9;+++[K7EJL4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465227}; Flags: Fragment;+++[K7EJL6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465229}; Flags: Fragment;+++[K7EJZ7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465393}; Flags: Fragment;+++[K7ES01_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000468485}; Flags: Fragment;"]
[100142659,"'CTAGE8'",41.94,20.67,12.49,25.0333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0042954///lipoprotein transporter activity","GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0042953///lipoprotein transport","CTAGE family member 8","[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[CTGE8_HUMAN|Reviewed]RecName: Full=cTAGE family member 8; Short=Protein cTAGE-8;"]
[100144748,"'KLLN'",52,30,26,36,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003677///DNA binding","GO:0006915///apoptotic process+++GO:0007050///cell cycle arrest+++GO:0007049///cell cycle","killin, p53 regulated DNA replication inhibitor","[KILIN_HUMAN|Reviewed]RecName: Full=Killin;"]
[10015,"'PDCD6IP'",2182,2119,1939,2080,"04144///Endocytosis",{"$nulls":3},"GO:0001772///immunological synapse+++GO:0005923///bicellular tight junction+++GO:0042470///melanosome+++GO:0070971///endoplasmic reticulum exit site+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:1903561///extracellular vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0042641///actomyosin+++GO:0005815///microtubule organizing center+++GO:0005925///focal adhesion+++GO:0090543///Flemming body","GO:0048306///calcium-dependent protein binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0031871///proteinase activated receptor binding","GO:1903543///positive regulation of exosomal secretion+++GO:0070830///bicellular tight junction assembly+++GO:0007080///mitotic metaphase plate congression+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:0019058///viral life cycle+++GO:0016032///viral process+++GO:0046755///viral budding+++GO:1903551///regulation of extracellular exosome assembly+++GO:0015031///protein transport+++GO:0006997///nucleus organization+++GO:0000281///mitotic cytokinesis+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0007049///cell cycle+++GO:1901673///regulation of mitotic spindle assembly+++GO:0000915///actomyosin contractile ring assembly+++GO:0039702///viral budding via host ESCRT complex+++GO:0051260///protein homooligomerization+++GO:0010824///regulation of centrosome duplication+++GO:0036258///multivesicular body assembly+++GO:1903553///positive regulation of extracellular exosome assembly+++GO:0006915///apoptotic process+++GO:0090559///regulation of membrane permeability+++GO:0061952///midbody abscission+++GO:0051301///cell division","programmed cell death 6 interacting protein","[PDC6I_HUMAN|Reviewed]RecName: Full=Programmed cell death 6-interacting protein; Short=PDCD6-interacting protein; AltName: Full=ALG-2-interacting protein 1; AltName: Full=ALG-2-interacting protein X; AltName: Full=Hp95;+++[C9IZF9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000406693}; Flags: Fragment;+++[F8WBR8_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000398895};+++[F8WDK9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000415150};+++[F8WEQ7_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000393777};+++[Q4W4Y1_HUMAN|Unreviewed]SubName: Full=Dopamine receptor interacting protein 4 {ECO:0000313|EMBL:AAQ14260.1};"]
[10016,"'PDCD6'",470,528,498,498.666666666667,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030127///COPII vesicle coat+++GO:0070062///extracellular exosome+++GO:0005768///endosome+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0015629///actin cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0060090///molecular adaptor activity+++GO:0005509///calcium ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0000287///magnesium ion binding+++GO:0004378///GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0102704///GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity","GO:1902527///positive regulation of protein monoubiquitination+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0014029///neural crest formation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097502///mannosylation+++GO:0006486///protein glycosylation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0001525///angiogenesis+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0034605///cellular response to heat+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006886///intracellular protein transport+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006915///apoptotic process+++GO:0051592///response to calcium ion+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0014032///neural crest cell development+++GO:0045766///positive regulation of angiogenesis+++GO:0010595///positive regulation of endothelial cell migration","programmed cell death 6","[PDCD6_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 6; AltName: Full=Apoptosis-linked gene 2 protein homolog {ECO:0000250|UniProtKB:P12815}; Short=ALG-2 {ECO:0000250|UniProtKB:P12815};+++[A0A024QZ42_HUMAN|Unreviewed]SubName: Full=HCG1985580, isoform CRA_c {ECO:0000313|EMBL:EAW50990.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000485024};+++[A0A087WZ38_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000482332};+++[D6RA21_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000424201};+++[E7EPW6_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000426003};+++[H0Y9X3_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000425370}; Flags: Fragment;+++[Q53FC3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6 variant {ECO:0000313|EMBL:BAD97086.1}; Flags: Fragment;+++[Q86W51_HUMAN|Unreviewed]SubName: Full=PDCD6 protein {ECO:0000313|EMBL:AAH50597.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000422691};"]
[10017,"'BCL2L10'",4,3,6,4.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0089720///caspase binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0007283///spermatogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007292///female gamete generation","BCL2 like 10","[B2L10_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 10; Short=Bcl2-L-10; AltName: Full=Anti-apoptotic protein NrH; AltName: Full=Apoptosis regulator Bcl-B;+++[H0YMD5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 10 {ECO:0000313|Ensembl:ENSP00000453562};"]
[100170229,"'SRRM5'",5,5,2,4,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","serine/arginine repetitive matrix 5","[SRRM5_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 5;+++[Q4G0Z0_HUMAN|Unreviewed]SubName: Full=LOC100170229 protein {ECO:0000313|EMBL:AAH34980.1}; Flags: Fragment;"]
[100170841,"'EPOP'",91,73,61,75,{"$nulls":4},"GO:0070449///elongin complex+++GO:0035098///ESC/E(Z) complex+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0003682///chromatin binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0048863///stem cell differentiation+++GO:0048663///neuron fate commitment","elongin BC and polycomb repressive complex 2 associated protein","[EPOP_HUMAN|Reviewed]RecName: Full=Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8}; AltName: Full=Proline-rich protein 28 {ECO:0000312|HGNC:HGNC:34493};"]
[10018,"'BCL2L11'",109,82,114,101.666666666667,"04210///Apoptosis+++05206///MicroRNAs in cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++04215///Apoptosis - multiple species+++01521///EGFR tyrosine kinase inhibitor resistance+++05210///Colorectal cancer+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0005829///cytosol+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex+++GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097140///BIM-BCL-xl complex+++GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0097141///BIM-BCL-2 complex","GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0019901///protein kinase binding","GO:0008584///male gonad development+++GO:0048536///spleen development+++GO:0035148///tube formation+++GO:0001822///kidney development+++GO:0048538///thymus development+++GO:0009791///post-embryonic development+++GO:0001783///B cell apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0007420///brain development+++GO:0045787///positive regulation of cell cycle+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0048066///developmental pigmentation+++GO:0002262///myeloid cell homeostasis+++GO:0001701///in utero embryonic development+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0032464///positive regulation of protein homooligomerization+++GO:0010942///positive regulation of cell death+++GO:0070242///thymocyte apoptotic process+++GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0007160///cell-matrix adhesion+++GO:0002260///lymphocyte homeostasis+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0001782///B cell homeostasis+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:0046620///regulation of organ growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0030879///mammary gland development+++GO:0043583///ear development+++GO:0006915///apoptotic process+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0043029///T cell homeostasis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0001776///leukocyte homeostasis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043065///positive regulation of apoptotic process+++GO:0034263///positive regulation of autophagy in response to ER overload+++GO:0048070///regulation of developmental pigmentation+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0007283///spermatogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0060154///cellular process regulating host cell cycle in response to virus+++GO:0060139///positive regulation of apoptotic process by virus","BCL2 like 11","[B2L11_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 11; Short=Bcl2-L-11; AltName: Full=Bcl2-interacting mediator of cell death;+++[A0A0A0MRE7_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000350398};+++[A0A0C4DH20_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000354879};+++[C9J417_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000411870}; Flags: Fragment;+++[E9PAM9_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000376941}; Flags: Fragment;+++[H7BZE5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000389225}; Flags: Fragment;"]
[100188893,"'TOMM6'",705,595,643,647.666666666667,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005742///mitochondrial outer membrane translocase complex",null,"GO:0015031///protein transport","translocase of outer mitochondrial membrane 6","[TOM6_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM6 homolog; AltName: Full=Overexpressed breast tumor protein; AltName: Full=Translocase of outer membrane 6 kDa subunit homolog;"]
[10019,"'SH2B3'",177,202,171,183.333333333333,"04722///Neurotrophin signaling pathway","H00408///Type I diabetes mellitus",null,null,"GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0035591///signaling adaptor activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding","GO:0007596///blood coagulation+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0009967///positive regulation of signal transduction+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0035162///embryonic hemopoiesis","SH2B adaptor protein 3","[SH2B3_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 3; AltName: Full=Lymphocyte adapter protein; AltName: Full=Lymphocyte-specific adapter protein Lnk; AltName: Full=Signal transduction protein Lnk;+++[B7Z7K6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54917, highly similar to Lymphocyte-specific adapter protein Lnk {ECO:0000313|EMBL:BAH13642.1};+++[F5GYM4_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000440597};+++[Q59H48_HUMAN|Unreviewed]SubName: Full=Lymphocyte adaptor protein variant {ECO:0000313|EMBL:BAD92148.1}; Flags: Fragment;+++[Q96BA5_HUMAN|Unreviewed]SubName: Full=SH2B3 protein {ECO:0000313|EMBL:AAH15786.1};+++[R4GN84_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000473529}; Flags: Fragment;"]
[100190949,"'C5orf52'",1,0,2,1,{"$nulls":7},"chromosome 5 open reading frame 52","[CE052_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf52;"]
[100191040,"'C2CD4D'",9,13,12,11.3333333333333,{"$nulls":4},"GO:0098793///presynapse+++GO:0005886///plasma membrane","GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding",null,"C2 calcium dependent domain containing 4D","[C2D4D_HUMAN|Reviewed]RecName: Full=C2 calcium-dependent domain-containing protein 4D;"]
[1002,"'CDH4'",118,88,104,103.333333333333,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0016342///catenin complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007411///axon guidance+++GO:0045773///positive regulation of axon extension+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization","cadherin 4","[CADH4_HUMAN|Reviewed]RecName: Full=Cadherin-4; AltName: Full=Retinal cadherin; Short=R-CAD; Short=R-cadherin; Flags: Precursor;+++[A0A087WX99_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000480844};+++[A0A0G2JRA4_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000486568}; Flags: Fragment;"]
[10020,"'GNE'",260,216.19,227,234.396666666667,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H00596///Nonaka distal myopathy (NM)+++H00594///Distal myopathy+++H00147///Sialuria",null,"R02705///ATP:N-acyl-D-mannosamine 6-phosphotransferase   ATP + N-Acetyl-D-mannosamine <=> ADP + N-Acetyl-D-mannosamine 6-phosphate+++R00414///UDP-N-acetyl-D-glucosamine 2-epimerase   UDP-N-acetyl-alpha-D-glucosamine + H2O <=> N-Acetyl-D-mannosamine + UDP","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008761///UDP-N-acetylglucosamine 2-epimerase activity+++GO:0009384///N-acylmannosamine kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity+++GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0008152///metabolic process+++GO:0006054///N-acetylneuraminate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006045///N-acetylglucosamine biosynthetic process+++GO:0007155///cell adhesion+++GO:0016310///phosphorylation","glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase","[GLCNE_HUMAN|Reviewed]RecName: Full=Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; AltName: Full=UDP-GlcNAc-2-epimerase/ManAc kinase; Includes: RecName: Full=UDP-N-acetylglucosamine 2-epimerase (hydrolyzing); EC=3.2.1.183; AltName: Full=UDP-GlcNAc-2-epimerase; AltName: Full=Uridine diphosphate-N-acetylglucosamine-2-epimerase; Includes: RecName: Full=N-acetylmannosamine kinase; EC=2.7.1.60; AltName: Full=ManAc kinase;+++[Q6QNY5_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59259.1};+++[Q6QNY6_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59258.1};+++[Q6QNY7_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59257.1};"]
[10021,"'HCN4'",15,9,16,13.3333333333333,"04024///cAMP signaling pathway+++04742///Taste transduction","H00729///Sick sinus syndrome (SSS)+++H00728///Brugada syndrome (BRS)",null,null,"GO:0098855///HCN channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0005267///potassium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0042802///identical protein binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0030552///cAMP binding+++GO:0005249///voltage-gated potassium channel activity+++GO:0086041///voltage-gated potassium channel activity involved in SA node cell action potential depolarization+++GO:0000166///nucleotide binding+++GO:0005272///sodium channel activity","GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0071321///cellular response to cGMP+++GO:0006813///potassium ion transport+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0008015///blood circulation+++GO:0071805///potassium ion transmembrane transport+++GO:0086015///SA node cell action potential+++GO:0098719///sodium ion import across plasma membrane+++GO:0003254///regulation of membrane depolarization+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0006936///muscle contraction+++GO:0034765///regulation of ion transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0002027///regulation of heart rate+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential","hyperpolarization activated cyclic nucleotide gated potassium channel 4","[HCN4_HUMAN|Reviewed]RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4;"]
[10022,"'INSL5'",0,1,0,0.333333333333333,"04926///Relaxin signaling pathway",{"$nulls":3},"GO:0005575///cellular_component+++GO:0005576///extracellular region","GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity","GO:0008150///biological_process+++GO:0010469///regulation of signaling receptor activity+++GO:2000253///positive regulation of feeding behavior+++GO:0007186///G protein-coupled receptor signaling pathway","insulin like 5","[INSL5_HUMAN|Reviewed]RecName: Full=Insulin-like peptide INSL5; Short=Insulin-like peptide 5; Contains: RecName: Full=Insulin-like peptide INSL5 B chain; Contains: RecName: Full=Insulin-like peptide INSL5 A chain; Flags: Precursor;"]
[10023,"'FRAT1'",31,25,11,22.3333333333333,"05200///Pathways in cancer+++05225///Hepatocellular carcinoma+++04310///Wnt signaling pathway+++05224///Breast cancer+++05226///Gastric cancer",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding","GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0060070///canonical Wnt signaling pathway+++GO:1904886///beta-catenin destruction complex disassembly","FRAT1, WNT signaling pathway regulator","[FRAT1_HUMAN|Reviewed]RecName: Full=Proto-oncogene FRAT1; AltName: Full=Frequently rearranged in advanced T-cell lymphomas 1; Short=FRAT-1;+++[D3DR49_HUMAN|Unreviewed]SubName: Full=Frequently rearranged in advanced T-cell lymphomas, isoform CRA_a {ECO:0000313|EMBL:EAW49951.1};"]
[10024,"'TROAP'",0,1,5,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0007155///cell adhesion","trophinin associated protein","[TROAP_HUMAN|Reviewed]RecName: Full=Tastin; AltName: Full=Trophinin-assisting protein; AltName: Full=Trophinin-associated protein;+++[B7Z5Q9_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000450306}; SubName: Full=cDNA FLJ50628, highly similar to Trophinin-associated protein {ECO:0000313|EMBL:BAH12995.1};+++[F8VR46_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446564};+++[F8VVS4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449588}; Flags: Fragment;+++[F8VVT5_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449245};+++[F8VVX4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449866};+++[F8VXF3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449984};+++[F8VXV6_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449032};+++[F8W052_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447244}; Flags: Fragment;+++[F8W130_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447509};+++[F8W1E3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446646}; Flags: Fragment;+++[F8W1U0_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447421};"]
[10025,"'MED16'",1050,1100,1140,1096.66666666667,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005634///nucleus","GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0003824///catalytic activity+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042809///vitamin D receptor binding","GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030518///intracellular steroid hormone receptor signaling pathway","mediator complex subunit 16","[MED16_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16; AltName: Full=Mediator complex subunit 16; AltName: Full=Thyroid hormone receptor-associated protein 5; AltName: Full=Thyroid hormone receptor-associated protein complex 95 kDa component; Short=Trap95; AltName: Full=Vitamin D3 receptor-interacting protein complex 92 kDa component; Short=DRIP92;+++[A0A087WU12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YW49_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXA0_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000488370}; Flags: Fragment;+++[A0A0J9YXK9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXL6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YY02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YYC6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ7_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i4 {ECO:0000313|EMBL:ACB88883.1}; Flags: Fragment;+++[B9TWZ8_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX00_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX01_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX03_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i10 {ECO:0000313|EMBL:ACB88889.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000480766}; Flags: Fragment;+++[B9TX04_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX05_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX06_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX07_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i14 {ECO:0000313|EMBL:ACB88893.1}; Flags: Fragment;+++[B9TX08_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i15 {ECO:0000313|EMBL:ACB88894.1}; Flags: Fragment;+++[B9TX09_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX10_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i17 {ECO:0000313|EMBL:ACB88896.1}; Flags: Fragment;+++[B9TX11_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX13_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i20 {ECO:0000313|EMBL:ACB88899.1}; Flags: Fragment;+++[B9TX14_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i21 {ECO:0000313|EMBL:ACB88900.1};+++[B9TX15_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i22 {ECO:0000313|EMBL:ACB88901.1}; Flags: Fragment;+++[B9TX16_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i23 {ECO:0000313|EMBL:ACB88902.1};+++[B9TX17_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i24 {ECO:0000313|EMBL:ACB88903.1};+++[B9TX18_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i25 {ECO:0000313|EMBL:ACB88904.1};+++[B9TX19_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i26 {ECO:0000313|EMBL:ACB88905.1};+++[B9TX20_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i27 {ECO:0000313|EMBL:ACB88906.1};+++[B9TX21_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i28 {ECO:0000313|EMBL:ACB88907.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000483533};+++[B9TX22_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i29 {ECO:0000313|EMBL:ACB88908.1};+++[B9TX23_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i30 {ECO:0000313|EMBL:ACB88909.1};+++[B9TX24_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i31 {ECO:0000313|EMBL:ACB88910.1};+++[B9TX25_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i32 {ECO:0000313|EMBL:ACB88911.1};+++[B9TX26_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX27_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i34 {ECO:0000313|EMBL:ACB88913.1};+++[B9TX28_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i35 {ECO:0000313|EMBL:ACB88914.1};+++[K7EKS6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[K7EKX2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465823};+++[K7EKX6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465827}; Flags: Fragment;+++[U3KQ43_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[U3KQB4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;"]
[10026,"'PIGK'",685,508,572,588.333333333333,"01100///Metabolic pathways+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis",{"$nulls":3},"GO:0042765///GPI-anchor transamidase complex+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0003923///GPI-anchor transamidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0003756///protein disulfide isomerase activity+++GO:0016787///hydrolase activity+++GO:0034235///GPI anchor binding+++GO:0005515///protein binding","GO:0006508///proteolysis+++GO:0016255///attachment of GPI anchor to protein+++GO:0006506///GPI anchor biosynthetic process","phosphatidylinositol glycan anchor biosynthesis class K","[GPI8_HUMAN|Reviewed]RecName: Full=GPI-anchor transamidase; Short=GPI transamidase; EC=3.-.-.-; AltName: Full=GPI8 homolog; Short=hGPI8; AltName: Full=Phosphatidylinositol-glycan biosynthesis class K protein; Short=PIG-K; Flags: Precursor;+++[A6NEM5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000352041};+++[B1AK81_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000388854}; SubName: Full=Phosphatidylinositol glycan, class K, isoform CRA_c {ECO:0000313|EMBL:EAX06382.1};+++[S4R3M5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000474518}; Flags: Fragment;"]
[100271715,"'ARHGEF33'",9,4,3,5.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0035023///regulation of Rho protein signal transduction","Rho guanine nucleotide exchange factor 33","[ARG33_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 33;+++[H7C1C9_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 33 {ECO:0000313|Ensembl:ENSP00000399688};"]
[100271849,"'MEF2B'",24.02,63.89,40.86,42.9233333333333,"04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway","H01613///Follicular lymphoma",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0042826///histone deacetylase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007517///muscle organ development","myocyte enhancer factor 2B","[MEF2B_HUMAN|Reviewed]RecName: Full=Myocyte-specific enhancer factor 2B; AltName: Full=RSRFR2; AltName: Full=Serum response factor-like protein 2;+++[A0A024R7K5_HUMAN|Unreviewed]SubName: Full=MADS box transcription enhancer factor 2, polypeptide B (Myocyte enhancer factor 2B), isoform CRA_a {ECO:0000313|EMBL:EAW84793.1};+++[B3KQ23_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386480}; SubName: Full=cDNA FLJ32648 fis, clone SYNOV2001451, highly similar to MYOCYTE-SPECIFIC ENHANCER FACTOR 2B {ECO:0000313|EMBL:BAG51885.1};+++[B8ZZJ5_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386784};+++[C9J4J4_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386374};"]
[100271927,"'RASA4B'",157.07,124.7,150.05,143.94,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0005543///phospholipid binding+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0071277///cellular response to calcium ion+++GO:0043087///regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction","RAS p21 protein activator 4B","[RAS4B_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4B;+++[F5GXT2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000440982};+++[F8W6L0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000303968};"]
[100272147,"'CMC4'",101.52,102.42,138,113.98,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0032991///protein-containing complex","GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0008283///cell proliferation","C-X9-C motif containing 4","[CMC4_HUMAN|Reviewed]RecName: Full=Cx9C motif-containing protein 4; AltName: Full=Mature T-cell proliferation 1 neighbor protein; AltName: Full=Mature T-cell proliferation-1 type A; Short=MTCP-1 type A; AltName: Full=Protein p8 MTCP-1; Short=p8MTCP1;+++[A0A0G2JKI4_HUMAN|Unreviewed]SubName: Full=Protein p13 MTCP-1 {ECO:0000313|Ensembl:ENSP00000427132}; Flags: Fragment;+++[Q9NRK3_HUMAN|Unreviewed]SubName: Full=p8 protein {ECO:0000313|EMBL:AAF76750.1};"]
[100287036,"'LOC100287036'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol",null,"GO:0060325///face morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001894///tissue homeostasis+++GO:0035264///multicellular organism growth+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0060348///bone development","uncharacterized LOC100287036","[B7Z1S9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59013 {ECO:0000313|EMBL:BAH11615.1};"]
[100287171,"'WASHC1'",3672,3390,3863,3641.66666666667,"04212///Longevity regulating pathway - worm+++04144///Endocytosis",{"$nulls":3},"GO:0071203///WASH complex+++GO:0005814///centriole+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005829///cytosol+++GO:0071437///invadopodium+++GO:0055038///recycling endosome membrane+++GO:0000145///exocyst+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005856///cytoskeleton+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005776///autophagosome+++GO:0031410///cytoplasmic vesicle","GO:0043014///alpha-tubulin binding+++GO:0003779///actin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0015031///protein transport+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0010507///negative regulation of autophagy+++GO:0030335///positive regulation of cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0006887///exocytosis+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031396///regulation of protein ubiquitination+++GO:0022617///extracellular matrix disassembly+++GO:0042147///retrograde transport, endosome to Golgi+++GO:1990126///retrograde transport, endosome to plasma membrane","WASH complex subunit 1","[WASH1_HUMAN|Reviewed]RecName: Full=WASH complex subunit 1 {ECO:0000312|HGNC:HGNC:24361}; AltName: Full=CXYorf1-like protein on chromosome 9; AltName: Full=Protein FAM39E; AltName: Full=WAS protein family homolog 1;+++[A0A2R8YDD3_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 1 {ECO:0000313|Ensembl:ENSP00000494459}; Flags: Fragment;+++[A9QQ12_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71499.1}; Flags: Fragment;+++[A9QQ13_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71500.1}; Flags: Fragment;+++[A9QQ14_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71501.1}; Flags: Fragment;+++[A9QQ15_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71502.1}; Flags: Fragment;+++[A9QQ16_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71503.1}; Flags: Fragment;+++[A9QQ17_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71504.1}; Flags: Fragment;+++[A9QQ18_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71505.1}; Flags: Fragment;+++[A9QQ19_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71506.1}; Flags: Fragment;+++[A9QQ20_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71507.1}; Flags: Fragment;+++[A9QQ21_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71508.1}; Flags: Fragment;+++[A9QQ22_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71509.1}; Flags: Fragment;+++[A9QQ23_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71510.1}; Flags: Fragment;"]
[100287387,"'LOC100287387'",0,0,1,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0003677///DNA binding+++GO:0046983///protein dimerization activity","GO:0043066///negative regulation of apoptotic process+++GO:0006351///transcription, DNA-templated+++GO:0030335///positive regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045668///negative regulation of osteoblast differentiation","uncharacterized LOC100287387","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[TWIST_XENLA|diamond]RecName: Full=Twist-related protein; AltName: Full=T18; AltName: Full=X-twist;+++[TWST1_EULFU|diamond]RecName: Full=Twist-related protein 1;+++[TWST2_HUMAN|diamond]RecName: Full=Twist-related protein 2; AltName: Full=Class A basic helix-loop-helix protein 39; Short=bHLHa39; AltName: Full=Dermis-expressed protein 1; Short=Dermo-1;+++[TWST2_MOUSE|diamond]RecName: Full=Twist-related protein 2; AltName: Full=Dermis-expressed protein 1; Short=Dermo-1;+++[TWST2_RAT|diamond]RecName: Full=Twist-related protein 2;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100287482,"'SMKR1'",11,10,14,11.6666666666667,{"$nulls":7},"small lysine rich protein 1","[SMKR1_HUMAN|Reviewed]RecName: Full=Small lysine-rich protein 1;"]
[100287896,"'LOC100287896'",57,33,55,48.3333333333333,"04140///Autophagy - animal+++00785///Lipoic acid metabolism+++04137///Mitophagy - animal+++01100///Metabolic pathways",null,null,"R07769///lipoyl-[acp]:protein N6-lipoyltransferase Lipoyl-[acp] + Apoprotein <=> Protein N6-(lipoyl)lysine + Acyl-carrier protein+++R07766///octanoyl-[acp]:protein N6-octanoyltransferase Octanoyl-[acp] + Apoprotein <=> Protein N6-(octanoyl)lysine + Acyl-carrier protein","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0033819///lipoyl(octanoyl) transferase activity+++GO:0016874///ligase activity+++GO:0102555///octanoyl transferase activity (acting on glycine-cleavage complex H protein)","GO:0009249///protein lipoylation+++GO:0034641///cellular nitrogen compound metabolic process+++GO:2000376///positive regulation of oxygen metabolic process","uncharacterized LOC100287896","[Q8TB74_HUMAN|Unreviewed]SubName: Full=Similar to Cytochrome c, somatic {ECO:0000313|EMBL:AAH19340.1};"]
[100287898,"'TTC34'",9,7,14,10,{"$nulls":7},"tetratricopeptide repeat domain 34","[TTC34_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 34; Short=TPR repeat protein 34;+++[A0A1C7CYW7_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 34 {ECO:0000313|Ensembl:ENSP00000383873};"]
[100287932,"'TIMM23'",808.52,703.75,791.76,768.01,"04212///Longevity regulating pathway - worm","H00032///Thyroid cancer",null,null,"GO:0016021///integral component of membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031305///integral component of mitochondrial inner membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport","translocase of inner mitochondrial membrane 23","[TIM23_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim23;+++[Q6X2S9_HUMAN|Unreviewed]SubName: Full=Translocase of the inner mitochondrial membrane {ECO:0000313|EMBL:AAP83315.1}; Flags: Fragment;"]
[100288142,"'NBPF20'",552.42,448.27,437.85,479.513333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0003723///RNA binding",null,"NBPF member 20","[NBPFK_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 20;+++[A0A075B7A3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000471335};+++[A0A087WU97_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000478481};+++[H7BY70_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000358380};"]
[100288332,"'NPIPA5'",268.55,268.01,272.33,269.63,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"nuclear pore complex interacting protein family member A5","[NPIA5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[A0A067ZUK6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28873.1}; Flags: Fragment;+++[A0A067ZUK7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28878.1}; Flags: Fragment;+++[A0A067ZUK9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28883.1}; Flags: Fragment;+++[A0A067ZUL0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28888.1}; Flags: Fragment;+++[A0A067ZUL2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28893.1}; Flags: Fragment;+++[A0A067ZUL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28898.1}; Flags: Fragment;+++[A0A067ZUL5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28903.1}; Flags: Fragment;+++[A0A067ZUL6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28908.1}; Flags: Fragment;+++[A0A067ZUL8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28913.1}; Flags: Fragment;+++[A0A067ZVG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28875.1}; Flags: Fragment;+++[A0A067ZVG5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28880.1}; Flags: Fragment;+++[A0A067ZVG8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28885.1}; Flags: Fragment;+++[A0A067ZVH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28890.1}; Flags: Fragment;+++[A0A067ZVH5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28895.1}; Flags: Fragment;+++[A0A067ZVH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28900.1}; Flags: Fragment;+++[A0A067ZVI1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28905.1}; Flags: Fragment;+++[A0A067ZVI6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28910.1}; Flags: Fragment;+++[A0A067ZWN6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28874.1}; Flags: Fragment;+++[A0A067ZWN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28879.1}; Flags: Fragment;+++[A0A067ZWP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28884.1}; Flags: Fragment;+++[A0A067ZWP4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28889.1}; Flags: Fragment;+++[A0A067ZWP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28894.1}; Flags: Fragment;+++[A0A067ZWQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28899.1}; Flags: Fragment;+++[A0A067ZWQ3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28904.1}; Flags: Fragment;+++[A0A067ZWQ8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28909.1}; Flags: Fragment;+++[A0A067ZWR0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28914.1}; Flags: Fragment;+++[A0A067ZXG0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28872.1}; Flags: Fragment;+++[A0A067ZXG1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28877.1}; Flags: Fragment;+++[A0A067ZXG4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28882.1}; Flags: Fragment;+++[A0A067ZXG6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28887.1}; Flags: Fragment;+++[A0A067ZXG7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28892.1}; Flags: Fragment;+++[A0A067ZXH0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28897.1}; Flags: Fragment;+++[A0A067ZXH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28902.1}; Flags: Fragment;+++[A0A067ZXH4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28907.1}; Flags: Fragment;+++[A0A067ZXH7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28912.1}; Flags: Fragment;+++[A0A067ZXH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28917.1}; Flags: Fragment;+++[A0A067ZXM6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28876.1}; Flags: Fragment;+++[A0A067ZXN0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28881.1}; Flags: Fragment;+++[A0A067ZXN4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28886.1}; Flags: Fragment;+++[A0A067ZXN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28891.1}; Flags: Fragment;+++[A0A067ZXP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28896.1}; Flags: Fragment;+++[A0A067ZXP5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28901.1}; Flags: Fragment;+++[A0A067ZXP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28906.1}; Flags: Fragment;+++[A0A067ZXQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28911.1}; Flags: Fragment;+++[A0A0B4J1W7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000389275};+++[A0A0J9YW65_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000487831}; Flags: Fragment;+++[A0A0J9YWV6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000488135};+++[E9PJ88_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435611};+++[H0YED6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435610}; Flags: Fragment;+++[H0YEP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000436257}; Flags: Fragment;+++[H0YF59_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000437314}; Flags: Fragment;+++[Q9NRE7_HUMAN|Unreviewed]SubName: Full=KIAA0220-like protein {ECO:0000313|EMBL:AAF82267.1}; SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000330634};"]
[100288413,"'ERVMER34-1'",146,120,140,135.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region",null,null,"endogenous retrovirus group MER34 member 1, envelope","[MER34_HUMAN|Reviewed]RecName: Full=Endogenous retroviral envelope protein HEMO {ECO:0000305}; AltName: Full=Endogenous retrovirus group MER34 member 1 Env polyprotein {ECO:0000305}; AltName: Full=HERV-MER_4q12 provirus ancestral Env polyprotein; AltName: Full=Human endogenous MER34 (medium-reiteration-frequency-family-34) open reading frame {ECO:0000303|PubMed:28739914}; AltName: Full=Human endogenous MER34 ORF {ECO:0000303|PubMed:28739914}; Short=HEMO {ECO:0000303|PubMed:28739914}; Contains: RecName: Full=Endogenous retroviral envelope protein HEMO, secreted form {ECO:0000305}; AltName: Full=Endogenous retroviral envelope protein HEMO, 48 kDa form; Flags: Precursor;"]
[100288687,"'DUX4'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005829///cytosol","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0008285///negative regulation of cell proliferation+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0006351///transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II","double homeobox 4","[DUX4_HUMAN|Reviewed]RecName: Full=Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}; AltName: Full=Double homeobox protein 10 {ECO:0000312|EMBL:AAK91509.1};+++[A0A2H4V0R9_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:AUA60622.1};+++[C3U395_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACN62209.1};+++[C3U396_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30487.1};+++[C3U397_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30488.1};+++[C3U398_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACN62210.1};+++[C3U399_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30489.1};+++[C3U3A0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30490.1}; SubName: Full=Double homeodomain protein DUX4-fl {ECO:0000313|EMBL:ADN68615.1};+++[E0YLM6_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK45392.1}; Flags: Fragment;+++[E0Z3E7_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24689.1};+++[E0Z3E8_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24690.1};+++[E0Z3E9_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24691.1};+++[E0Z3F0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24692.1};+++[E0Z3F1_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24693.1};+++[E0Z3F3_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24695.1}; SubName: Full=DUX4L {ECO:0000313|EMBL:AUA60219.1}; Flags: Fragment;+++[E0Z3F7_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24699.1}; Flags: Fragment;+++[E0Z3G4_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24706.1};+++[E0Z3H0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24712.1};+++[E0Z3H2_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24714.1};+++[E0Z3H5_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24717.1};+++[E2JJS1_HUMAN|Unreviewed]SubName: Full=Double homeobox protein 4 {ECO:0000313|Ensembl:ENSP00000455112}; SubName: Full=Double homeodomain protein DUX4-s {ECO:0000313|EMBL:ADN68617.1};+++[F8QWT8_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24684.1};+++[F8QWU0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24685.1};+++[F8QWU1_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24683.1};+++[F8QWU2_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24688.1};"]
[100288695,"'LIMS4'",37.12,16.66,8.65,20.81,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0045216///cell-cell junction organization","LIM zinc finger domain containing 4","[LIMS3_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 3; AltName: Full=Particularly interesting new Cys-His protein 3; Short=PINCH-3;+++[LIMS4_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 4; AltName: Full=LIM and senescent cell antigen-like-containing domain protein 3-like;+++[A0A0J9YXC7_HUMAN|Unreviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein {ECO:0000256|PIRNR:PIRNR038003};"]
[100288814,"'CLDN34'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0005923///bicellular tight junction+++GO:0016020///membrane","GO:0005198///structural molecule activity",null,"claudin 34","[CLD34_HUMAN|Reviewed]RecName: Full=Claudin-34 {ECO:0000305};"]
[100288960,"'PRSS43'",1,1,5,2.33333333333333,"04137///Mitophagy - animal+++05410///Hypertrophic cardiomyopathy (HCM)+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04140///Autophagy - animal+++04260///Cardiac muscle contraction","H00292///Hypertrophic cardiomyopathy (HCM)",null,null,"GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006508///proteolysis","serine protease 43","[PRS43_HUMAN|Reviewed]RecName: Full=Putative inactive serine protease 43 {ECO:0000305}; Flags: Precursor;"]
[100289187,"'TMEM225B'",2,2,0,1.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0010923///negative regulation of phosphatase activity","transmembrane protein 225B","[T225B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 225B {ECO:0000312|HGNC:HGNC:53075};"]
[100289279,"'CNTNAP3C'",80.47,59.18,38.79,59.48,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region",null,"GO:0008037///cell recognition+++GO:0007155///cell adhesion","contactin associated protein like 3C","[CNT3B_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3B; AltName: Full=Cell recognition molecule Caspr3b; Flags: Precursor;+++[CNTP3_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3; AltName: Full=Cell recognition molecule Caspr3; Flags: Precursor;+++[CNTP4_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP4_MOUSE|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP5_CHICK|diamond]RecName: Full=Contactin-associated protein-like 5; AltName: Full=Cell recognition molecule Caspr5; Flags: Precursor;"]
[100289561,"'LOC100289561'",102.21,80.86,78.08,87.05,{"$nulls":4},"GO:0032389///MutLalpha complex","GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding","GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0006298///mismatch repair+++GO:0006355///regulation of transcription, DNA-templated","uncharacterized LOC100289561","[PM2P3_HUMAN|diamond]RecName: Full=Putative postmeiotic segregation increased 2-like protein 3; AltName: Full=PMS2-related protein 3; AltName: Full=Postmeiotic segregation increased 2-like protein 9; AltName: Full=Postmeiotic segregation increased protein 5; AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 3;+++[RBAK_HUMAN|diamond]RecName: Full=RB-associated KRAB zinc finger protein; AltName: Full=RB-associated KRAB repressor; Short=hRBaK; AltName: Full=Zinc finger protein 769;+++[ZN510_HUMAN|diamond]RecName: Full=Zinc finger protein 510;+++[ZNF12_HUMAN|diamond]RecName: Full=Zinc finger protein 12; AltName: Full=Gonadotropin-inducible ovary transcription repressor 3; Short=GIOT-3; AltName: Full=Zinc finger protein 325; AltName: Full=Zinc finger protein KOX3;+++[ZNF12_MOUSE|diamond]RecName: Full=Zinc finger protein 12;"]
[100289635,"'ZNF605'",347,235,257,279.666666666667,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 605","[ZN605_HUMAN|Reviewed]RecName: Full=Zinc finger protein 605;+++[Q8WW51_HUMAN|Unreviewed]SubName: Full=ZNF605 protein {ECO:0000313|EMBL:AAH20877.1}; Flags: Fragment;"]
[100289678,"'ZNF783'",151,142.97,158,150.656666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger family member 783","[ZN783_HUMAN|Reviewed]RecName: Full=Protein ZNF783;"]
[100293516,"'ZNF587B'",43.72,49.78,37.27,43.59,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 587B","[Z587B_HUMAN|Reviewed]RecName: Full=Zinc finger protein 587B;+++[M0QY62_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000469623};+++[M0R1N2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000472004}; Flags: Fragment;"]
[100293534,"'C4B_2'",113.11,127.41,214.37,151.63,"05150///Staphylococcus aureus infection+++05322///Systemic lupus erythematosus+++05133///Pertussis+++04610///Complement and coagulation cascades","H00102///Classic complement pathway component defects+++H00080///Systemic lupus erythematosus+++H01649///Schizophrenia",null,null,"GO:0030054///cell junction+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0072562///blood microparticle+++GO:0043025///neuronal cell body+++GO:0005886///plasma membrane+++GO:0044216///other organism cell","GO:0001848///complement binding+++GO:0030246///carbohydrate binding+++GO:0004252///serine-type endopeptidase activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0001849///complement component C1q binding","GO:2000427///positive regulation of apoptotic cell clearance+++GO:0043687///post-translational protein modification+++GO:0008228///opsonization+++GO:0030449///regulation of complement activation+++GO:0032490///detection of molecule of bacterial origin+++GO:0044267///cellular protein metabolic process+++GO:0006954///inflammatory response+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response+++GO:0006956///complement activation","complement component 4B (Chido blood group), copy 2","[CO4B_HUMAN|Reviewed]RecName: Full=Complement C4-B; AltName: Full=Basic complement C4; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; Contains: RecName: Full=Complement C4 beta chain; Contains: RecName: Full=Complement C4-B alpha chain; Contains: RecName: Full=C4a anaphylatoxin; Contains: RecName: Full=C4b-B; Contains: RecName: Full=C4d-B; Contains: RecName: Full=Complement C4 gamma chain; Flags: Precursor;+++[A0A0G2JL54_HUMAN|Unreviewed]SubName: Full=Complement C4-B {ECO:0000313|Ensembl:ENSP00000449433};"]
[100302652,"'GPR75-ASB3'",72.47,23.39,86.75,60.87,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0035556///intracellular signal transduction+++GO:0016567///protein ubiquitination","GPR75-ASB3 readthrough","[ASB3_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 3; Short=ASB-3;+++[A0A0A6YYF3_HUMAN|Unreviewed]SubName: Full=Protein GPR75-ASB3 {ECO:0000313|Ensembl:ENSP00000385085};"]
[100302736,"'TMED7-TICAM2'",100.03,94.71,74.87,89.87,"05161///Hepatitis B+++04620///Toll-like receptor signaling pathway+++05133///Pertussis+++04064///NF-kappa B signaling pathway+++04217///Necroptosis",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030134///COPII-coated ER to Golgi transport vesicle","GO:0005543///phospholipid binding","GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization","TMED7-TICAM2 readthrough","[TCAM2_HUMAN|Reviewed]RecName: Full=TIR domain-containing adapter molecule 2; Short=TICAM-2; AltName: Full=Putative NF-kappa-B-activating protein 502; AltName: Full=TRIF-related adapter molecule; AltName: Full=Toll-like receptor adaptor protein 3; AltName: Full=Toll/interleukin-1 receptor domain-containing protein; Short=MyD88-4;+++[TMED7_HUMAN|Reviewed]RecName: Full=Transmembrane emp24 domain-containing protein 7; AltName: Full=p24 family protein gamma-3; Short=p24gamma3; AltName: Full=p27; Flags: Precursor;+++[A0A0A6YYA0_HUMAN|Unreviewed]SubName: Full=Protein TMED7-TICAM2 {ECO:0000313|Ensembl:ENSP00000333650};"]
[100303755,"'PET117'",54.66,37.01,60.39,50.6866666666667,{"$nulls":4},"GO:0005739///mitochondrion","GO:0004402///histone acetyltransferase activity+++GO:0030274///LIM domain binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","PET117 homolog","[PT117_HUMAN|Reviewed]RecName: Full=Protein PET117 homolog, mitochondrial; Flags: Precursor;+++[L0R6F6_HUMAN|Unreviewed]SubName: Full=Alternative protein CSRP2BP {ECO:0000313|EMBL:CCO13715.1};"]
[100310812,"'SPDYE2B'",1,4,4.21,3.07,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",null,null,"GO:0005737///cytoplasm+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane+++GO:0005829///cytosol","GO:0019901///protein kinase binding","GO:0046580///negative regulation of Ras protein signal transduction+++GO:0034260///negative regulation of GTPase activity+++GO:0045859///regulation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0071277///cellular response to calcium ion","speedy/RINGO cell cycle regulator family member E2B","[SPE2B_HUMAN|Reviewed]RecName: Full=Speedy protein E2B;"]
[100310846,"'ANKRD61'",0,1,0,0.333333333333333,{"$nulls":7},"ankyrin repeat domain 61","[ANR61_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 61;"]
[100316904,"'SAP25'",10,4,13,9,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0006355///regulation of transcription, DNA-templated","Sin3A associated protein 25","[SAP25_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP25; AltName: Full=25 kDa Sin3-associated polypeptide; AltName: Full=Sin3 corepressor complex subunit SAP25;+++[A0A087WYF9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP25 {ECO:0000313|Ensembl:ENSP00000481773};"]
[100329135,"'TRPC5OS'",0,0,1,0.333333333333333,{"$nulls":7},"TRPC5 opposite strand","[TR5OS_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein TRPC5OS; AltName: Full=TRPC5 opposite strand protein; AltName: Full=TRPC5-antisense RNA 1;"]
[10036,"'CHAF1A'",143,139,104,128.666666666667,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0033186///CAF-1 complex","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0070087///chromo shadow domain binding+++GO:0051082///unfolded protein binding+++GO:0003682///chromatin binding","GO:0031497///chromatin assembly+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006334///nucleosome assembly+++GO:0007049///cell cycle","chromatin assembly factor 1 subunit A","[CAF1A_HUMAN|Reviewed]RecName: Full=Chromatin assembly factor 1 subunit A; Short=CAF-1 subunit A; AltName: Full=Chromatin assembly factor I p150 subunit; Short=CAF-I 150 kDa subunit; Short=CAF-I p150; Short=hp150;+++[D6W625_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1, subunit A (P150), isoform CRA_a {ECO:0000313|EMBL:EAW69225.1};+++[K7EJF1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000465142}; Flags: Fragment;+++[K7EME9_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466475}; Flags: Fragment;+++[K7ENC7_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466888}; Flags: Fragment;+++[K7EPA1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000467296}; Flags: Fragment;"]
[10038,"'PARP2'",267,287,287,280.333333333333,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04210///Apoptosis+++04212///Longevity regulating pathway - worm",null,"M00296///BER complex",null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990404///protein ADP-ribosylase activity","GO:0006471///protein ADP-ribosylation+++GO:0006281///DNA repair+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0018312///peptidyl-serine ADP-ribosylation+++GO:1901215///negative regulation of neuron death","poly(ADP-ribose) polymerase 2","[PARP2_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 2; Short=PARP-2; Short=hPARP-2; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 2; Short=ARTD2; AltName: Full=NAD(+) ADP-ribosyltransferase 2; Short=ADPRT-2; AltName: Full=Poly[ADP-ribose] synthase 2; Short=pADPRT-2;+++[E9PJ27_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 2 {ECO:0000313|Ensembl:ENSP00000431867};+++[G3V167_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[H0YH02_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114}; Flags: Fragment;"]
[100381270,"'ZBED6'",155,54,68,92.3333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger BED-type containing 6","[ZBED6_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 6 {ECO:0000303|PubMed:20016685};"]
[10039,"'PARP3'",344,341,369,351.333333333333,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04212///Longevity regulating pathway - worm+++04210///Apoptosis",null,"M00296///BER complex",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0005815///microtubule organizing center+++GO:0005730///nucleolus+++GO:0005814///centriole+++GO:0005856///cytoskeleton","GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003824///catalytic activity+++GO:0016740///transferase activity","GO:0051106///positive regulation of DNA ligation+++GO:0060236///regulation of mitotic spindle organization+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0006281///DNA repair+++GO:1905662///negative regulation of telomerase RNA reverse transcriptase activity+++GO:0000723///telomere maintenance+++GO:0006471///protein ADP-ribosylation+++GO:1990166///protein localization to site of double-strand break","poly(ADP-ribose) polymerase family member 3","[PARP3_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 3; Short=PARP-3; Short=hPARP-3; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 3; Short=ARTD3; AltName: Full=IRT1; AltName: Full=NAD(+) ADP-ribosyltransferase 3; Short=ADPRT-3; AltName: Full=Poly[ADP-ribose] synthase 3; Short=pADPRT-3;+++[A0A024R2X5_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[C9J9C7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417625}; Flags: Fragment;+++[F8WAY7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417396};"]
[1004,"'CDH6'",178,144,90,137.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0009986///cell surface+++GO:0016342///catenin complex+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0034332///adherens junction organization","cadherin 6","[CADH6_HUMAN|Reviewed]RecName: Full=Cadherin-6; AltName: Full=Kidney cadherin; Short=K-cadherin; Flags: Precursor;+++[D6RF86_HUMAN|Unreviewed]SubName: Full=Cadherin-6 {ECO:0000313|Ensembl:ENSP00000424843};+++[L8EAC6_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH6 {ECO:0000313|EMBL:CCQ43288.1};"]
[10040,"'TOM1L1'",468,448,539,485,"04714///Thermogenesis+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++04137///Mitophagy - animal+++04140///Autophagy - animal",null,"M00154///Cytochrome c oxidase",null,"GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005623///cell+++GO:0005795///Golgi stack+++GO:0005768///endosome+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0043130///ubiquitin binding+++GO:0005515///protein binding+++GO:0030295///protein kinase activator activity+++GO:0017124///SH3 domain binding","GO:0006886///intracellular protein transport+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:2000278///regulation of DNA biosynthetic process+++GO:0015031///protein transport+++GO:0031954///positive regulation of protein autophosphorylation","target of myb1 like 1 membrane trafficking protein","[TM1L1_HUMAN|Reviewed]RecName: Full=TOM1-like protein 1; AltName: Full=Src-activating and signaling molecule protein; AltName: Full=Target of Myb-like protein 1;+++[I3L0N2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458219};+++[I3L1G1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458809}; Flags: Fragment;+++[I3L1Q1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459003}; Flags: Fragment;+++[I3L1T2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459079};+++[I3L367_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460213}; Flags: Fragment;+++[I3L3M3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460565};+++[I3L3T4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460721};+++[I3L4G0_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461215}; Flags: Fragment;+++[I3L4I4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461284};+++[I3L4N3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461396}; Flags: Fragment;+++[I3NI44_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461876};+++[J3KQU4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000408958}; SubName: Full=Target of myb1-like 1 (Chicken), isoform CRA_b {ECO:0000313|EMBL:EAW94552.1};+++[K7EP47_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000467227}; Flags: Fragment;+++[Q8NI65_HUMAN|Unreviewed]SubName: Full=OK/KNS-CL.3 {ECO:0000313|EMBL:BAB93522.1};"]
[10042,"'HMGXB4'",238,236,293,255.666666666667,{"$nulls":4},"GO:0016589///NURF complex+++GO:0005634///nucleus","GO:0003677///DNA binding","GO:0016055///Wnt signaling pathway+++GO:0008333///endosome to lysosome transport+++GO:0030178///negative regulation of Wnt signaling pathway","HMG-box containing 4","[HMGX4_HUMAN|Reviewed]RecName: Full=HMG domain-containing protein 4; AltName: Full=HMG box-containing protein 4; AltName: Full=High mobility group protein 2-like 1; AltName: Full=Protein HMGBCG;+++[B0QXZ8_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000415500}; Flags: Fragment;+++[B0QXZ9_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000401658}; Flags: Fragment;+++[F8WDU7_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000395532};+++[Q2M3X1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI04757.1}; SubName: Full=High-mobility group protein 2-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW60048.1};+++[Q2T9L2_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI11374.1}; Flags: Fragment;+++[Q6P681_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH62413.1}; Flags: Fragment;+++[Q6PJ09_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH25303.1}; Flags: Fragment;+++[Q6PJC1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH17326.1}; Flags: Fragment;+++[Q7Z641_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH52624.1}; Flags: Fragment;"]
[10043,"'TOM1'",1399,1473,1529,1467,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0005769///early endosome+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005623///cell+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0035577///azurophil granule membrane","GO:0030276///clathrin binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0043312///neutrophil degranulation+++GO:0016197///endosomal transport+++GO:0006897///endocytosis","target of myb1 membrane trafficking protein","[TOM1_HUMAN|Reviewed]RecName: Full=Target of Myb protein 1;+++[B0QY01_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000393714}; Flags: Fragment;+++[B0QY02_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000389789}; Flags: Fragment;+++[B3KUF5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39747 fis, clone SMINT2017432, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53417.1};+++[B3KUU1_HUMAN|Unreviewed]SubName: Full=Target of myb1 (Chicken), isoform CRA_a {ECO:0000313|EMBL:EAW60053.1}; SubName: Full=cDNA FLJ40607 fis, clone THYMU2012273, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53553.1};+++[F8WAW7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000385906};+++[F8WB30_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000397492};+++[F8WBB0_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000390429};+++[F8WE29_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000394944};+++[H7BYN7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000379085};+++[Q6UW50_HUMAN|Unreviewed]SubName: Full=TOM1 {ECO:0000313|EMBL:AAQ89339.1}; SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000371465};+++[V9GYF4_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000476698}; Flags: Fragment;+++[V9GZ68_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000477471}; Flags: Fragment;"]
[10044,"'SH2D3C'",9,7,7,7.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0098793///presynapse+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004102///choline O-acetyltransferase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005070///SH3/SH2 adaptor activity","GO:0007254///JNK cascade+++GO:0007269///neurotransmitter secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0008292///acetylcholine biosynthetic process+++GO:0009967///positive regulation of signal transduction+++GO:0007274///neuromuscular synaptic transmission+++GO:0007264///small GTPase mediated signal transduction+++GO:0042136///neurotransmitter biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process","SH2 domain containing 3C","[SH2D3_HUMAN|Reviewed]RecName: Full=SH2 domain-containing protein 3C; AltName: Full=Novel SH2-containing protein 3; AltName: Full=SH2 domain-containing Eph receptor-binding protein 1; Short=SHEP1;+++[A0A1W2PP46_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000491328};+++[A0A1W2PRG4_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000492646};+++[B4DG32_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59318, highly similar to SH2 domain-containing protein 3C {ECO:0000313|EMBL:BAG57643.1};+++[H0Y5X5_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3C {ECO:0000313|Ensembl:ENSP00000401641}; Flags: Fragment;+++[Q5JU32_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3C {ECO:0000313|Ensembl:ENSP00000413760}; Flags: Fragment;+++[R4GN13_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000473443};"]
[10045,"'SH2D3A'",48,38,36,40.6666666666667,"04910///Insulin signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0005622///intracellular+++GO:0005764///lysosome+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0005794///Golgi apparatus+++GO:0001891///phagocytic cup","GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005070///SH3/SH2 adaptor activity","GO:0007254///JNK cascade+++GO:0007264///small GTPase mediated signal transduction+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0009967///positive regulation of signal transduction","SH2 domain containing 3A","[SH23A_HUMAN|Reviewed]RecName: Full=SH2 domain-containing protein 3A; AltName: Full=Novel SH2-containing protein 1;+++[A8K2M8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78700, highly similar to Homo sapiens SH2 domain containing 3A, mRNA {ECO:0000313|EMBL:BAF82982.1};+++[M0QZQ6_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000470700}; Flags: Fragment;"]
[10046,"'MAMLD1'",601,657,695,651,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00609///46,XY disorders of sex development (Other)",null,null,"GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008584///male gonad development","mastermind like domain containing 1","[MAMD1_HUMAN|Reviewed]RecName: Full=Mastermind-like domain-containing protein 1; AltName: Full=F18; AltName: Full=Protein CG1;+++[F8WAK3_HUMAN|Unreviewed]SubName: Full=Mastermind-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000351765}; Flags: Fragment;+++[L0R6K4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAMLD1 {ECO:0000313|EMBL:CCO13767.1};"]
[100462977,"'MTRNR2L1'",2732.05,2976.31,2686.73,2798.36333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 1","[HMN1_HUMAN|Reviewed]RecName: Full=Humanin-like 1 {ECO:0000305}; Short=HN1 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 1 {ECO:0000312|HGNC:HGNC:37155};"]
[100462981,"'MTRNR2L2'",170622.47,171053.48,161293.73,167656.56,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 2","[HMN2_HUMAN|Reviewed]RecName: Full=Humanin-like 2 {ECO:0000305}; Short=HN2 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 2 {ECO:0000312|HGNC:HGNC:37156};"]
[100462983,"'MTRNR2L3'",786.45,795.08,863.77,815.1,"03013///RNA transport+++05164///Influenza A",null,"M00427///Nuclear pore complex",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 3","[HMN3_HUMAN|Reviewed]RecName: Full=Humanin-like 3 {ECO:0000305}; Short=HN3 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 3 {ECO:0000312|HGNC:HGNC:37157};"]
[100463482,"'MTRNR2L6'",642.33,693.61,663.01,666.316666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 6","[HMN6_HUMAN|Reviewed]RecName: Full=Humanin-like 6 {ECO:0000305}; Short=HN6 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 6 {ECO:0000312|HGNC:HGNC:37163};"]
[100463486,"'MTRNR2L8'",93893.84,96787.3,95161.99,95281.0433333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","MT-RNR2 like 8","[HMN8_HUMAN|Reviewed]RecName: Full=Humanin-like 8 {ECO:0000305}; Short=HN8 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 8 {ECO:0000312|HGNC:HGNC:37165};"]
[100463487,"'MTRNR2L9'",1218.44,1324.93,1114.72,1219.36333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 9","[HMN9_HUMAN|Reviewed]RecName: Full=Humanin-like 9 {ECO:0000305}; Short=HN9 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 9 {ECO:0000312|HGNC:HGNC:37166};"]
[100463488,"'MTRNR2L10'",427.4,503.28,425.06,451.913333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","MT-RNR2 like 10","[HMN10_HUMAN|Reviewed]RecName: Full=Humanin-like 10 {ECO:0000305}; Short=HN10 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 10 {ECO:0000312|HGNC:HGNC:37167};"]
[10048,"'RANBP9'",852,797,778,809,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex","GO:0019899///enzyme binding+++GO:0008536///Ran GTPase binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007020///microtubule nucleation+++GO:0007411///axon guidance+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000165///MAPK cascade","RAN binding protein 9","[RANB9_HUMAN|Reviewed]RecName: Full=Ran-binding protein 9; Short=RanBP9; AltName: Full=BPM-L; AltName: Full=BPM90; AltName: Full=Ran-binding protein M; Short=RanBPM {ECO:0000303|PubMed:11470507, ECO:0000303|PubMed:17467196}; AltName: Full=RanBP7;+++[A0A024QZW3_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_a {ECO:0000313|EMBL:EAW55345.1};+++[A0A024R014_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_b {ECO:0000313|EMBL:EAW55344.1};"]
[10049,"'DNAJB6'",1860,1722,1566,1716,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0031072///heat shock protein binding+++GO:0001671///ATPase activator activity+++GO:0042802///identical protein binding+++GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0060710///chorio-allantoic fusion+++GO:0032781///positive regulation of ATPase activity+++GO:1900034///regulation of cellular response to heat+++GO:0060715///syncytiotrophoblast cell differentiation involved in labyrinthine layer development+++GO:0090084///negative regulation of inclusion body assembly+++GO:0030198///extracellular matrix organization+++GO:0030036///actin cytoskeleton organization+++GO:0006457///protein folding+++GO:0045109///intermediate filament organization+++GO:0060717///chorion development+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated","DnaJ heat shock protein family (Hsp40) member B6","[DNJB6_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily B member 6; AltName: Full=HHDJ1; AltName: Full=Heat shock protein J2; Short=HSJ-2; AltName: Full=MRJ; AltName: Full=MSJ-1;+++[A0A0J9YX62_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000488263};+++[C9J2C4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000400665}; Flags: Fragment;+++[C9J2P2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000410643}; Flags: Fragment;+++[C9JB42_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000391690}; Flags: Fragment;+++[C9JDR7_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396240}; Flags: Fragment;+++[C9JDX6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000403407}; Flags: Fragment;+++[C9JN01_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000389599}; Flags: Fragment;+++[E9PH18_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396267};+++[F8WCZ4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000415201};+++[Q49A72_HUMAN|Unreviewed]SubName: Full=DNAJB6 protein {ECO:0000313|EMBL:AAH43270.1};+++[Q75MP3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DNAJB6 {ECO:0000313|EMBL:AAS07521.1}; Flags: Fragment;"]
[100499483,"'CCDC180'",75,78,74,75.6666666666667,{"$nulls":4},"GO:0070062///extracellular exosome",null,null,"coiled-coil domain containing 180","[CC180_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 180;+++[B4DZK1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50036, weakly similar to Myosin-11 {ECO:0000313|EMBL:BAG64113.1};"]
[1005,"'CDH7'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0034332///adherens junction organization+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 7","[CADH7_HUMAN|Reviewed]RecName: Full=Cadherin-7; Flags: Precursor;+++[F5H5X9_HUMAN|Unreviewed]SubName: Full=Cadherin-7 {ECO:0000313|Ensembl:ENSP00000443030};+++[Q8IY78_HUMAN|Unreviewed]SubName: Full=CDH7 protein {ECO:0000313|EMBL:AAH36786.1};"]
[100505385,"'IQCJ-SCHIP1'",993.75,1046.45,746.48,928.893333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0043194///axon initial segment+++GO:0030424///axon","GO:0005515///protein binding","GO:0051494///negative regulation of cytoskeleton organization","IQCJ-SCHIP1 readthrough","[IQIP1_HUMAN|Reviewed]RecName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000312|HGNC:HGNC:38842};+++[A0A1W2PP08_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491220}; Flags: Fragment;+++[A0A1W2PPY3_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491419}; Flags: Fragment;+++[A0A1W2PQT1_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492132}; Flags: Fragment;+++[A0A1W2PR78_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492358}; Flags: Fragment;+++[A0A1W2PR91_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492497}; Flags: Fragment;+++[A0A1W2PRV6_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492461}; Flags: Fragment;+++[A0A1W2PRY4_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492853}; Flags: Fragment;+++[C9J366_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000417305};"]
[100505549,"'LOC100505549'",7,4,5,5.33333333333333,{"$nulls":7},"uncharacterized LOC100505549","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100505573,"'INAFM2'",440,391,513,448,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005246///calcium channel regulator activity",null,"InaF motif containing 2","[INAM2_HUMAN|Reviewed]RecName: Full=Putative transmembrane protein INAFM2 {ECO:0000305}; AltName: Full=InaF-motif-containing protein 2 {ECO:0000312|HGNC:HGNC:35165}; AltName: Full=Osteogenesis up-regulated transcript 1 {ECO:0000303|PubMed:19531736};"]
[100505591,"'LRRC3C'",3,2,3,2.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space","GO:0043565///sequence-specific DNA binding+++GO:0004860///protein kinase inhibitor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0043312///neutrophil degranulation+++GO:0090156///cellular sphingolipid homeostasis+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0006672///ceramide metabolic process+++GO:1900060///negative regulation of ceramide biosynthetic process+++GO:0006351///transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0019221///cytokine-mediated signaling pathway","leucine rich repeat containing 3C","[LRR3C_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 3C; Flags: Precursor;"]
[100505679,"'UBE2Q2L'",2,5,3,3.33333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031258///lamellipodium membrane+++GO:0070062///extracellular exosome+++GO:0005925///focal adhesion+++GO:0005796///Golgi lumen+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0043202///lysosomal lumen","GO:0019901///protein kinase binding","GO:0030206///chondroitin sulfate biosynthetic process+++GO:0048771///tissue remodeling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030207///chondroitin sulfate catabolic process+++GO:0035556///intracellular signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001525///angiogenesis+++GO:0000187///activation of MAPK activity+++GO:0008283///cell proliferation+++GO:0008347///glial cell migration","ubiquitin conjugating enzyme E2 Q2 like","[U2Q2L_HUMAN|Reviewed]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;"]
[100505753,"'KRTAP16-1'",0,0,3,1,{"$nulls":4},"GO:0005882///intermediate filament+++GO:0005829///cytosol+++GO:0045095///keratin filament",null,"GO:0031424///keratinization","keratin associated protein 16-1","[KR161_HUMAN|Reviewed]RecName: Full=Keratin-associated protein 16-1;"]
[100505767,"'SPDYE18'",0,2,2.81,1.60333333333333,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E18","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPDE7_HUMAN|diamond]RecName: Full=Putative speedy protein E7; AltName: Full=Speedy protein E7 pseudogene;+++[SPDL3_HUMAN|diamond]RecName: Full=Putative speedy protein-like protein 3;"]
[100505841,"'LOC100505841'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding",null,"zinc finger protein 474-like","[A0A1B0GTH9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000489710};+++[A0A1B0GW86_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490823}; Flags: Fragment;+++[A0A1B0GWJ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490947};"]
[100505876,"'CEBPZOS'",570.01,603.84,631.25,601.7,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","CEBPZ opposite strand","[CEBOS_HUMAN|Reviewed]RecName: Full=Protein CEBPZOS {ECO:0000305}; AltName: Full=CEBPZ antisense RNA 1 {ECO:0000312|HGNC:HGNC:49288}; AltName: Full=CEBPZ opposite strand {ECO:0000312|HGNC:HGNC:49288};"]
[100505989,"'SMIM31'",1,1,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"small integral membrane protein 31","[SIM31_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 31 {ECO:0000305};"]
[100505993,"'TMEM210'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 210","[TM210_HUMAN|Reviewed]RecName: Full=Transmembrane protein 210; Flags: Precursor;+++[H3BNS5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 210 {ECO:0000313|Ensembl:ENSP00000454984};"]
[100506012,"'PPP5D1'",17.99,15.02,18.06,17.0233333333333,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005622///intracellular","GO:0005509///calcium ion binding","GO:0019722///calcium-mediated signaling","PPP5 tetratricopeptide repeat domain containing 1","[PP5D1_HUMAN|Reviewed]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[A0A087WY80_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000481586}; Flags: Fragment;+++[M0R196_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000471730}; Flags: Fragment;"]
[100506084,"'ARL17B'",138.02,161.65,91.71,130.46,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport","ADP ribosylation factor like GTPase 17B","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[A8K0M5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76374 {ECO:0000313|EMBL:BAF82279.1};+++[I3L1A0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000458681}; Flags: Fragment;+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L2E4_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459606};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};+++[Q9BVU5_HUMAN|Unreviewed]SubName: Full=ARL17 protein {ECO:0000313|EMBL:AAH00924.2}; Flags: Fragment;"]
[100506115,"'SMIM25'",26,30,51,35.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"small integral membrane protein 25","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100506127,"'GVQW3'",62.58,61.04,62.93,62.1833333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding","GO:0008285///negative regulation of cell proliferation+++GO:0007165///signal transduction","GVQW motif containing 3","[GVQW3_HUMAN|Reviewed]RecName: Full=Protein GVQW3 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 3 {ECO:0000305};+++[A0A0U1RQW1_HUMAN|Unreviewed]SubName: Full=Protein GVQW3 {ECO:0000313|Ensembl:ENSP00000489195};"]
[100506144,"'TMEM35B'",187,167,213,189,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 35B","[TM35B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 35B; AltName: Full=ZMYM6 neighbor protein; Flags: Precursor;"]
[100506164,"'HSFX1'",0,0,13,4.33333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0061408///positive regulation of transcription from RNA polymerase II promoter in response to heat stress+++GO:0006355///regulation of transcription, DNA-templated+++GO:0034605///cellular response to heat","heat shock transcription factor family, X-linked 1","[HSFX1_HUMAN|Reviewed]RecName: Full=Heat shock transcription factor, X-linked;+++[A0A140VK21_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 21 {ECO:0000313|EMBL:AEE61158.1};"]
[100506243,"'KRBOX1'",34,30,20,28,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","KRAB box domain containing 1","[KRBX1_HUMAN|Reviewed]RecName: Full=KRAB domain-containing protein 1;+++[A0A024R2N1_HUMAN|Unreviewed]SubName: Full=HCG2039480, isoform CRA_a {ECO:0000313|EMBL:EAW64687.1};"]
[100506248,"'PTMAP9'",714.02,781.89,685.45,727.12,"05169///Epstein-Barr virus infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0042393///histone binding+++GO:0033613///activating transcription factor binding","GO:0043486///histone exchange+++GO:0006351///transcription, DNA-templated","prothymosin alpha pseudogene 9","[PTMA_BOVIN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_HUMAN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_MOUSE|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_PONAB|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_RAT|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;"]
[100506514,"'LOC100506514'",0,0,5,1.66666666666667,{"$nulls":4},"GO:0005622///intracellular","GO:0005525///GTP binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity","GO:0006164///purine nucleotide biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process","uncharacterized LOC100506514","[ZKSC2_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 2; AltName: Full=Zinc finger protein 694;+++[ZSC20_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31; AltName: Full=Zinc finger protein 360; AltName: Full=Zinc finger protein KOX29;+++[ZSC20_MOUSE|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31;+++[ZSC29_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 29; AltName: Full=Zinc finger protein 690;"]
[100506540,"'SPTY2D1OS'",0,0,1,0.333333333333333,"00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00010///Glycolysis / Gluconeogenesis+++01120///Microbial metabolism in diverse environments+++00640///Propanoate metabolism+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00620///Pyruvate metabolism+++04922///Glucagon signaling pathway","H01762///Muscle glycogen storage disease+++H00069///Glycogen storage diseases (GSD)+++H01946///Glycogen storage disease type XI",null,"R00703///(S)-Lactate:NAD+ oxidoreductase (S)-Lactate + NAD+ <=> Pyruvate + NADH + H++++R03104///3-Mercaptolactate:NAD+ oxidoreductase 3-Mercaptolactate + NAD+ <=> Mercaptopyruvate + NADH + H++++R01000///2-hydroxybutyrate:NAD+ oxidoreductase 2-Hydroxybutanoic acid + NAD+ <=> 2-Oxobutanoate + NADH + H+","GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0015031///protein transport+++GO:0006915///apoptotic process+++GO:0005975///carbohydrate metabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006464///cellular protein modification process+++GO:0043065///positive regulation of apoptotic process+++GO:0019752///carboxylic acid metabolic process","SPTY2D1 opposite strand","[SPTOS_HUMAN|Reviewed]RecName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000305}; AltName: Full=SPTY2D1 antisense RNA 1 {ECO:0000312|HGNC:HGNC:44122}; AltName: Full=SPTY2D1 opposite strand {ECO:0000312|HGNC:HGNC:44122};+++[A0A0U1RQQ8_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489122};+++[A0A0U1RQZ7_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489253};+++[A0A0U1RR47_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489337};"]
[100506564,"'THEGL'",8,4,18,10,{"$nulls":7},"theg spermatid protein like","[THEGL_HUMAN|Reviewed]RecName: Full=Testicular haploid expressed gene protein-like; AltName: Full=Theg spermatid-like protein;"]
[100506571,"'LOC100506571'",0,2,2,1.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100506571","[Q9NT86_HUMAN|Unreviewed]SubName: Full=HCG42237 {ECO:0000313|EMBL:EAW69830.1};"]
[100506581,"'C16orf95'",32,50,38,40,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"chromosome 16 open reading frame 95","[CP095_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C16orf95;+++[A0A087X224_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000484646};+++[H3BNZ7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000455079};"]
[100506658,"'OCLN'",80,88,96,88,"04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++05160///Hepatitis C","H00840///Band-like calcification with simplified gyration and polymicrogyria (BLC-PMG)",null,null,"GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005911///cell-cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0005923///bicellular tight junction+++GO:0016327///apicolateral plasma membrane+++GO:0030139///endocytic vesicle+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0070673///response to interleukin-18+++GO:0045216///cell-cell junction organization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0065003///protein-containing complex assembly+++GO:2000810///regulation of bicellular tight junction assembly+++GO:0070830///bicellular tight junction assembly","occludin","[OCLN_HUMAN|Reviewed]RecName: Full=Occludin;+++[A0A0G2JMZ8_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};+++[A0A0G2JPF2_HUMAN|Unreviewed]SubName: Full=Occludin {ECO:0000313|Ensembl:ENSP00000483480};+++[A8K3T2_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};"]
[100507027,"'MRLN'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum","GO:0004857///enzyme inhibitor activity+++GO:0005179///hormone activity+++GO:0031788///motilin receptor binding","GO:1902081///negative regulation of calcium ion import into sarcoplasmic reticulum+++GO:0043086///negative regulation of catalytic activity+++GO:0009611///response to wounding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010469///regulation of signaling receptor activity","myoregulin","[MLN_HUMAN|Reviewed]RecName: Full=Myoregulin {ECO:0000303|PubMed:25640239};"]
[100507050,"'TPBGL'",3,5,0,2.66666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"trophoblast glycoprotein like","[TPBGL_HUMAN|Reviewed]RecName: Full=Trophoblast glycoprotein-like; Flags: Precursor;"]
[100507055,"'LRCOL1'",2,5,10,5.66666666666667,{"$nulls":4},"GO:0005576///extracellular region","GO:0008047///enzyme activator activity","GO:0043085///positive regulation of catalytic activity+++GO:0007586///digestion+++GO:0032094///response to food+++GO:0016042///lipid catabolic process","leucine rich colipase like 1","[LRCL1_HUMAN|Reviewed]RecName: Full=Leucine-rich colipase-like protein 1; Flags: Precursor;+++[A0A087WT69_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000477635};+++[A0A087WYD7_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000481713};+++[A0A087WZ94_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000482471};"]
[100507203,"'SMLR1'",0,0,3,1,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"small leucine rich protein 1","[SMLR1_HUMAN|Reviewed]RecName: Full=Small leucine-rich protein 1;"]
[100507290,"'ZNF865'",1192,1321,1199.02,1237.34,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","zinc finger protein 865","[ZN865_HUMAN|Reviewed]RecName: Full=Zinc finger protein 865;+++[A0A0D9SG26_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 865 {ECO:0000313|Ensembl:ENSP00000487098};"]
[100507421,"'TMEM178B'",503,316,285,368,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","transmembrane protein 178B","[T178B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 178B; Flags: Precursor;+++[A0A087X1B3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 178B {ECO:0000313|Ensembl:ENSP00000484025};"]
[100507436,"'MICA'",2835,3158,2540,2844.33333333333,"05167///Kaposi's sarcoma-associated herpesvirus infection","H00288///Familial Mediterranean fever (FMF)",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0030881///beta-2-microglobulin binding","GO:0050776///regulation of immune response+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0051607///defense response to virus+++GO:0009408///response to heat+++GO:0046629///gamma-delta T cell activation+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0030101///natural killer cell activation+++GO:0019835///cytolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0032815///negative regulation of natural killer cell activation+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042742///defense response to bacterium+++GO:0016032///viral process+++GO:0002418///immune response to tumor cell+++GO:0001913///T cell mediated cytotoxicity","MHC class I polypeptide-related sequence A",{"$cut":{"chars":22248,"head":"[MICA_HUMAN|Reviewed]RecName: Full=MHC class I polypeptide-related sequence A; Short=MIC-A; Flags: Precursor;+++[A0A023SER7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74089.1}; Flags: Fragment;+++[A0A023SGA8_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74088.1}; Flags: Fragment;+++[A0A024RCL3_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A, isoform CRA_a {ECO:0000313|EMBL:EAX03394.1};+++[A0A0F6UUZ2_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I chain-related protein A {ECO:0000313|EMBL:AKE78870.1}; Flags: Fragment;+++[A0A0G2JJ55_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000405177};+++[A0A0G2JK11_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000412992};+++[A0A0K1NWU9_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75046.1}; Flags: Fragment;+++[A0A0K1NXC7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75047.1}; Flags: Fragment;+++[A0A0K1NXW1_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75045.1}; Flags: Fragment;+++[A0A0M3LAT3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11906.1}; Flags: Fragment;+++[A0A0M3LAU3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11916.1}; Flags: Fragment;+++[A0A0M3LAV0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11908.1}; Flags: Fragment;+++[A0A0M3LAV5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11926.1}; Flags: Fragment;+++[A0A0M3LAW0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11918.1}; Flags: Fragment;+++[A0A0M3LAW3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11936.1}; Flags: Fragment;+++[A0A0M3LAW8_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11928.1}; Flags: Fragment;+++[A0A0M3LAX6_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11938.1}; Flags: Fragment;+++[A0A0M3LAX7_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11946.1}; Flags: Fragment;+++[A0A0M3LAY5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11948.1}; Flags: Fragment;+++[A0A0M3LB05_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11905.1}; Flags: Fragment;+++[A0A0M3LB16_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11903.1}; Flags: Fragment;+++[A0A0M3LB17_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11915.1}; Flags: Fragment;+++[A0A0M3LB24_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11913.1}; Flags: Fragment;+++[A0A0M3LB25_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11925.1}; Flags: Fragment;+++[A0A0M3LB32_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11923.1}; Flags: Fragment;+++[A0A0M3LB33_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11935.1}; Flags: Fragment;+++[A0A0M3LB39_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11945.1}; Flags: Fragment;+++[A0A0M3LB40_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11933.1}; Flags: Fragment;+++[A0A0M3LB48_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11955.1}; Flags: Fragment;+++[A0A0M3LB49_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11943.1}; Flags: Fragment;+++[A0A0M3LB59_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11953.1}; Flags: Fragment;+++[A0A0M3LB64_HUMAN|Unreviewed]SubName: Ful"}}]
[100507462,"'GVQW2'",0,2,6,2.66666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","GVQW motif containing 2","[GVQW2_HUMAN|Reviewed]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};"]
[100507507,"'LOC100507507'",161,185,162,169.333333333333,{"$nulls":7},"uncharacterized LOC100507507","[A0A2J8V2S2_PONAB|diamond]SubName: Full=T0078241 isoform 1 {ECO:0000313|EMBL:PNJ51828.1};"]
[100507537,"'DWORF'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008047///enzyme activator activity","GO:1902082///positive regulation of calcium ion import into sarcoplasmic reticulum+++GO:0031449///regulation of slow-twitch skeletal muscle fiber contraction+++GO:1901894///regulation of calcium-transporting ATPase activity","DWARF open reading frame","[A0A1B0GTW0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000489859};"]
[100507588,"'TGFBR3L'",43,54,52,49.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transforming growth factor beta receptor 3 like","[TGR3L_HUMAN|Reviewed]RecName: Full=Transforming growth factor-beta receptor type 3-like protein; AltName: Full=TGF-beta receptor type-3-like protein; Short=TGFR-3L; AltName: Full=Transforming growth factor-beta receptor type III-like protein; Short=TGF-beta receptor type III-like protein;"]
[100507607,"'NPIPB9'",5.35,17.55,16.05,12.9833333333333,"01100///Metabolic pathways+++00650///Butanoate metabolism",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm",null,null,"nuclear pore complex interacting protein family member B9","[NPIB9_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B9;+++[F8VUA1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B9 {ECO:0000313|Ensembl:ENSP00000350444};"]
[100507747,"'C13orf46'",62,35,61,52.6666666666667,{"$nulls":7},"chromosome 13 open reading frame 46","[CM046_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C13orf46 {ECO:0000305};"]
[10051,"'SMC4'",196,136,170,167.333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005694///chromosome","GO:0003697///single-stranded DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0030261///chromosome condensation+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0051383///kinetochore organization+++GO:0045132///meiotic chromosome segregation+++GO:0000070///mitotic sister chromatid segregation+++GO:0010032///meiotic chromosome condensation+++GO:0051276///chromosome organization+++GO:0051301///cell division","structural maintenance of chromosomes 4","[SMC4_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 4; Short=SMC protein 4; Short=SMC-4; AltName: Full=Chromosome-associated polypeptide C; Short=hCAP-C; AltName: Full=XCAP-C homolog;+++[B3KXX5_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[C9IYK2_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418820}; Flags: Fragment;+++[C9J578_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417999}; Flags: Fragment;+++[C9J9E4_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417612}; Flags: Fragment;+++[C9JJ64_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420817}; Flags: Fragment;+++[C9JR83_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420121}; Flags: Fragment;+++[C9JVD8_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419360}; Flags: Fragment;+++[C9JWF0_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419247}; Flags: Fragment;+++[E9PD53_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[F8WCB7_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418434};+++[Q58F29_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH01557.1}; Flags: Fragment;+++[Q6NSG3_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH70161.1}; Flags: Fragment;+++[Q6P169_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH65259.1}; Flags: Fragment;"]
[100510707,"'TBC1D3J'",0,1.05,0,0.35,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0005622///intracellular","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity+++GO:0031338///regulation of vesicle fusion","TBC1 domain family member 3J","[TBC3D_HUMAN|diamond]RecName: Full=TBC1 domain family member 3D {ECO:0000312|HGNC:HGNC:28944};+++[TBC3F_HUMAN|diamond]RecName: Full=TBC1 domain family member 3F;+++[TBC3G_HUMAN|diamond]RecName: Full=TBC1 domain family member 3G;+++[TBC3I_HUMAN|diamond]RecName: Full=TBC1 domain family member 3I {ECO:0000312|HGNC:HGNC:32709};+++[TBC3K_HUMAN|diamond]RecName: Full=TBC1 domain family member 3K {ECO:0000312|HGNC:HGNC:51245};"]
[10052,"'GJC1'",222,161,208,197,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0014704///intercalated disc+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016021///integral component of membrane+++GO:0005922///connexin complex","GO:0086077///gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling+++GO:0005216///ion channel activity+++GO:0086020///gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling","GO:0086014///atrial cardiac muscle cell action potential+++GO:0086021///SA node cell to atrial cardiac muscle cell communication by electrical coupling+++GO:0048738///cardiac muscle tissue development+++GO:0048468///cell development+++GO:0007043///cell-cell junction assembly+++GO:0086053///AV node cell to bundle of His cell communication by electrical coupling+++GO:0006936///muscle contraction+++GO:0007268///chemical synaptic transmission+++GO:0016264///gap junction assembly+++GO:0007601///visual perception+++GO:0001570///vasculogenesis","gap junction protein gamma 1","[CXG1_HUMAN|Reviewed]RecName: Full=Gap junction gamma-1 protein; AltName: Full=Connexin-45; Short=Cx45; AltName: Full=Gap junction alpha-7 protein;"]
[100526664,"'LY75-CD302'",3.48,0,3.38,2.28666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0043130///ubiquitin binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0038023///signaling receptor activity+++GO:0008270///zinc ion binding","GO:0006955///immune response+++GO:0008284///positive regulation of cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:0006954///inflammatory response+++GO:0051865///protein autoubiquitination+++GO:0006897///endocytosis+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0050821///protein stabilization+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0002643///regulation of tolerance induction+++GO:1905524///negative regulation of protein autoubiquitination","LY75-CD302 readthrough","[LY75_HUMAN|Reviewed]RecName: Full=Lymphocyte antigen 75; Short=Ly-75; AltName: Full=C-type lectin domain family 13 member B; AltName: Full=DEC-205; AltName: Full=gp200-MR6; AltName: CD_antigen=CD205; Flags: Precursor;"]
[100526693,"'ARPC4-TTLL3'",240.31,215.64,216.31,224.086666666667,{"$nulls":4},"GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton","GO:0003779///actin binding+++GO:0070735///protein-glycine ligase activity","GO:0018094///protein polyglycylation+++GO:0006464///cellular protein modification process+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030041///actin filament polymerization+++GO:0030833///regulation of actin filament polymerization","ARPC4-TTLL3 readthrough","[A0A0A6YYG9_HUMAN|Unreviewed]SubName: Full=Protein ARPC4-TTLL3 {ECO:0000313|Ensembl:ENSP00000380427};+++[F8WCF6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000256|PIRNR:PIRNR039100};+++[F8WE39_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000402163};+++[H7C0A3_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000393764}; Flags: Fragment;"]
[100526694,"'MSANTD3-TMEFF1'",90.21,60.34,63.51,71.3533333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding","GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007517///muscle organ development","MSANTD3-TMEFF1 readthrough","[TEFF1_HUMAN|Reviewed]RecName: Full=Tomoregulin-1; Short=TR-1; AltName: Full=H7365; AltName: Full=Transmembrane protein with EGF-like and one follistatin-like domain; Flags: Precursor;+++[A0A0A6YYJ0_HUMAN|Unreviewed]SubName: Full=Protein MSANTD3-TMEFF1 {ECO:0000313|Ensembl:ENSP00000424768};"]
[100526737,"'RBM14-RBM4'",8.3,11.28,0,6.52666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0098534///centriole assembly+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0002190///cap-independent translational initiation+++GO:0008380///RNA splicing+++GO:0045087///innate immune response+++GO:0030154///cell differentiation+++GO:0032055///negative regulation of translation in response to stress+++GO:0017148///negative regulation of translation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002192///IRES-dependent translational initiation of linear mRNA+++GO:0045947///negative regulation of translational initiation+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0046685///response to arsenic-containing substance+++GO:0097167///circadian regulation of translation+++GO:0006397///mRNA processing+++GO:0035278///miRNA mediated inhibition of translation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0046822///regulation of nucleocytoplasmic transport","RBM14-RBM4 readthrough","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0A0MSL8_HUMAN|Unreviewed]SubName: Full=RBM14-RBM4 readthrough {ECO:0000313|Ensembl:ENSP00000395880};+++[A0A0A6YYI9_HUMAN|Unreviewed]SubName: Full=Protein RBM14-RBM4 {ECO:0000313|Ensembl:ENSP00000421279};"]
[100526739,"'CENPS-CORT'",51.61,71.54,50.43,57.86,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0071821///FANCM-MHF complex+++GO:0005576///extracellular region","GO:0046982///protein heterodimerization activity+++GO:0005179///hormone activity","GO:0010469///regulation of signaling receptor activity","CENPS-CORT readthrough","[CENPS_HUMAN|Reviewed]RecName: Full=Centromere protein S; Short=CENP-S; AltName: Full=Apoptosis-inducing TAF9-like domain-containing protein 1; AltName: Full=FANCM-associated histone fold protein 1 {ECO:0000303|PubMed:20347428}; AltName: Full=FANCM-interacting histone fold protein 1 {ECO:0000303|PubMed:20347429}; AltName: Full=Fanconi anemia-associated polypeptide of 16 kDa;+++[A0A087WT10_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000473401};+++[A0A0U1RQL5_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000489060}; SubName: Full=Centromere protein S {ECO:0000313|Ensembl:ENSP00000489524};"]
[100526740,"'ATP5MF-PTCD1'",0,50.17,0,16.7233333333333,{"$nulls":4},"GO:0005759///mitochondrial matrix","GO:0000049///tRNA binding","GO:0042780///tRNA 3'-end processing","ATP5MF-PTCD1 readthrough","[B4DJ38_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56092, highly similar to Pentatricopeptide repeat protein 1 {ECO:0000313|EMBL:BAG58700.1};+++[C9JJT5_HUMAN|Unreviewed]SubName: Full=ATP5MF-PTCD1 readthrough {ECO:0000313|Ensembl:ENSP00000416954};+++[G3V325_HUMAN|Unreviewed]SubName: Full=ATP5MF-PTCD1 readthrough {ECO:0000313|Ensembl:ENSP00000400168};"]
[100526760,"'ABHD14A-ACY1'",14,22.45,21.19,19.2133333333333,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01230///Biosynthesis of amino acids+++00220///Arginine biosynthesis+++01210///2-Oxocarboxylic acid metabolism+++01130///Biosynthesis of antibiotics","H01146///Aminoacylase 1 deficiency","M00028///Ornithine biosynthesis, glutamate => ornithine","R00669///N2-Acetyl-L-ornithine amidohydrolase   N-Acetylornithine + H2O <=> Acetate + L-Ornithine+++R10553///N-acetyl-L-cysteine-S-conjugate amidohydrolase (carboxylate-forming)   S-Substituted N-acetyl-L-cysteine + H2O <=> S-Substituted L-cysteine + Acetate","GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0004046///aminoacylase activity+++GO:0008237///metallopeptidase activity","GO:0006520///cellular amino acid metabolic process+++GO:0006508///proteolysis","ABHD14A-ACY1 readthrough","[A0A1B0GU64_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000489981};+++[A0A1B0GUT4_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490236};+++[A0A1B0GV31_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490353}; Flags: Fragment;+++[A0A1B0GVA5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490434}; Flags: Fragment;+++[A0A1B0GVC5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490460}; Flags: Fragment;+++[A0A1B0GVN8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490593}; Flags: Fragment;+++[A0A1B0GVQ8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490616}; Flags: Fragment;+++[A0A1B0GVW5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490680}; Flags: Fragment;+++[A0A1B0GW23_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490744}; Flags: Fragment;+++[A0A1B0GW28_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490750}; Flags: Fragment;+++[A0A1B0GWD9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490887};+++[B4DNW0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60317, highly similar to Aminoacylase-1 {ECO:0000313|EMBL:BAG60372.1};+++[C9JMV9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420487};+++[F2Z3Q0_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420395};"]
[100526761,"'CCDC169-SOHLH2'",15.53,0,0,5.17666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity","GO:0007283///spermatogenesis+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0009994///oocyte differentiation","CCDC169-SOHLH2 readthrough","[SOLH2_HUMAN|Reviewed]RecName: Full=Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2;"]
[100526767,"'RNF103-CHMP3'",16.37,0,0,5.45666666666667,"04217///Necroptosis+++04144///Endocytosis",null,"M00412///ESCRT-III complex",null,"GO:0031410///cytoplasmic vesicle+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0000815///ESCRT III complex+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016021///integral component of membrane+++GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005770///late endosome+++GO:0010494///cytoplasmic stress granule+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0031902///late endosome membrane","GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0031210///phosphatidylcholine binding+++GO:0050681///androgen receptor binding+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0003727///single-stranded RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:1990381///ubiquitin-specific protease binding+++GO:0003697///single-stranded DNA binding+++GO:0051213///dioxygenase activity+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0031490///chromatin DNA binding+++GO:0032452///histone demethylase activity","GO:0007034///vacuolar transport","RNF103-CHMP3 readthrough","[CHMP3_HUMAN|Reviewed]RecName: Full=Charged multivesicular body protein 3; AltName: Full=Chromatin-modifying protein 3; AltName: Full=Neuroendocrine differentiation factor; AltName: Full=Vacuolar protein sorting-associated protein 24; Short=hVps24;+++[A0A140T963_HUMAN|Unreviewed]SubName: Full=RNF103-CHMP3 readthrough {ECO:0000313|Ensembl:ENSP00000392995}; Flags: Fragment;"]
[100526772,"'TMEM110-MUSTN1'",25.99,13.65,0,13.2133333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005246///calcium channel regulator activity","GO:0042246///tissue regeneration+++GO:0035988///chondrocyte proliferation+++GO:0002062///chondrocyte differentiation","TMEM110-MUSTN1 readthrough","[A8MSY1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422941};+++[H0Y8V1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422189}; Flags: Fragment;"]
[100526783,"'C15orf38-AP3S2'",624.3,414.43,602.3,547.01,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030117///membrane coat+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051126///negative regulation of actin nucleation","C15orf38-AP3S2 readthrough","[A0A0A6YYH1_HUMAN|Unreviewed]SubName: Full=Protein C15orf38-AP3S2 {ECO:0000313|Ensembl:ENSP00000381377};+++[H0YL85_HUMAN|Unreviewed]SubName: Full=C15orf38-AP3S2 readthrough {ECO:0000313|Ensembl:ENSP00000453100}; Flags: Fragment;+++[H0YMK0_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588}; Flags: Fragment;"]
[100526835,"'FPGT-TNNI3K'",11.64,7.39,7.22,8.75,"00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H02125///Cardiac conduction disease with dilated cardiomyopathy",null,"R01951///GTP:beta-L-fucose-1-phosphate guanylyltransferase GTP + L-Fucose 1-phosphate <=> Diphosphate + GDP-L-fucose","GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade","FPGT-TNNI3K readthrough","[TNI3K_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase TNNI3K; EC=2.7.11.1; AltName: Full=Cardiac ankyrin repeat kinase; AltName: Full=Cardiac troponin I-interacting kinase; AltName: Full=TNNI3-interacting kinase;+++[A6NHC7_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000359930};+++[E9PKE1_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000433587}; Flags: Fragment;+++[V9GXZ4_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000450895};"]
[100526842,"'RPL17-C18orf32'",85.44,78.12,90.19,84.5833333333333,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0002181///cytoplasmic translation","RPL17-C18orf32 readthrough","[A0A0A0MRF8_HUMAN|Unreviewed]SubName: Full=RPL17-C18orf32 readthrough {ECO:0000313|Ensembl:ENSP00000352143};+++[A0A0A6YYL6_HUMAN|Unreviewed]SubName: Full=Protein RPL17-C18orf32 {ECO:0000313|Ensembl:ENSP00000463379};"]
[100527943,"'TGIF2-RAB5IF'",11.17,0,5.76,5.64333333333333,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","TGIF2-RAB5IF readthrough","[A0A0A6YYL0_HUMAN|Unreviewed]SubName: Full=Protein TGIF2-C20orf24 {ECO:0000313|Ensembl:ENSP00000454021};"]
[100527963,"'PMF1-BGLAP'",106.82,87.45,81.66,91.9766666666666,"04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0000818///nuclear MIS12/MIND complex+++GO:0005829///cytosol+++GO:0005667///transcription factor complex+++GO:0000444///MIS12/MIND type complex+++GO:0005794///Golgi apparatus+++GO:0005694///chromosome+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region","GO:0043522///leucine zipper domain binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding","GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006366///transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation","PMF1-BGLAP readthrough","[PMF1_HUMAN|Reviewed]RecName: Full=Polyamine-modulated factor 1; Short=PMF-1;+++[A0A087WT04_HUMAN|Unreviewed]SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000458021};+++[U3KQ54_HUMAN|Unreviewed]SubName: Full=HCG2044777 {ECO:0000313|EMBL:EAW52985.1}; SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000475561};+++[V9GYH6_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476760}; Flags: Fragment;+++[V9GYI0_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476770};"]
[100527978,"'TMEM56-RWDD3'",12.62,5.54,5.9,8.02,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0033235///positive regulation of protein sumoylation+++GO:1902073///positive regulation of hypoxia-inducible factor-1alpha signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","TMEM56-RWDD3 readthrough","[S4R3V7_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000474793}; Flags: Fragment;+++[S4R434_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000475025};"]
[100528020,"'FAM187A'",12,12,25,16.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"family with sequence similarity 187 member A","[F187A_HUMAN|Reviewed]RecName: Full=Ig-like V-type domain-containing protein FAM187A; Flags: Precursor;"]
[100528030,"'POC1B-GALNT4'",21.42,13.79,13.4,16.2033333333333,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0006486///protein glycosylation","POC1B-GALNT4 readthrough","[GALT4_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 4; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 4; Short=GalNAc-T4; Short=pp-GaNTase 4; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 4; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4;+++[F8VUJ3_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[F8VZB3_HUMAN|Unreviewed]SubName: Full=POC1B-GALNT4 readthrough {ECO:0000313|Ensembl:ENSP00000447754};"]
[100528062,"'ARMCX5-GPRASP2'",26.28,76.59,37.47,46.78,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0003697///single-stranded DNA binding+++GO:0001540///amyloid-beta binding+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity","GO:0050769///positive regulation of neurogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:1990172///G protein-coupled receptor catabolic process+++GO:0007611///learning or memory+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0006351///transcription, DNA-templated+++GO:0032197///transposition, RNA-mediated+++GO:0008333///endosome to lysosome transport+++GO:0051965///positive regulation of synapse assembly","ARMCX5-GPRASP2 readthrough","[GASP2_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 2; Short=GASP-2;"]
[100528064,"'NEDD8-MDP1'",10.79,4.09,0,4.96,"04144///Endocytosis+++04217///Necroptosis","H01202///Cataract","M00412///ESCRT-III complex",null,"GO:0030659///cytoplasmic vesicle membrane+++GO:0031902///late endosome membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0000815///ESCRT III complex+++GO:0030496///midbody+++GO:0030117///membrane coat+++GO:0005737///cytoplasm","GO:0016791///phosphatase activity","GO:0016311///dephosphorylation","NEDD8-MDP1 readthrough","[E9PL57_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000431482}; Flags: Fragment;+++[E9PS38_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000432117};+++[S4R3E9_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000474249};"]
[100529063,"'BCL2L2-PABPN1'",70.33,73.51,58.13,67.3233333333333,"03015///mRNA surveillance pathway+++05164///Influenza A","H00704///Oculopharyngeal muscular dystrophy (OPMD)",null,null,"GO:0005774///vacuolar membrane+++GO:0042405///nuclear inclusion body+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0031301///integral component of organelle membrane+++GO:0016607///nuclear speck+++GO:0005887///integral component of plasma membrane+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex","GO:0097718///disordered domain specific binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0070063///RNA polymerase binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043621///protein self-association+++GO:0051400///BH domain binding+++GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity","GO:0031124///mRNA 3'-end processing+++GO:0015891///siderophore transport+++GO:0060011///Sertoli cell proliferation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0006396///RNA processing+++GO:1904247///positive regulation of polynucleotide adenylyltransferase activity+++GO:0007283///spermatogenesis+++GO:0055072///iron ion homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006936///muscle contraction+++GO:0006397///mRNA processing+++GO:0006369///termination of RNA polymerase II transcription+++GO:0000165///MAPK cascade+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0046778///modification by virus of host mRNA processing+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage","BCL2L2-PABPN1 readthrough","[AR1_XENLA|diamond]RecName: Full=Apoptosis regulator R1; AltName: Full=XR1; Flags: Fragment;+++[B2CL2_BOVIN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_CANLF|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_HUMAN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_MOUSE|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W; AltName: Full=c98;+++[PAB2A_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-A; Short=PABP-2-A; Short=Poly(A)-binding protein 2-A; AltName: Full=Nuclear poly(A)-binding protein 1-A; AltName: Full=Poly(A)-binding protein II-A; Short=PABII-A; AltName: Full=Polyadenylate-binding nuclear protein 1-A; AltName: Full=XLnPABP2-A; AltName: Full=nPABP2-A; AltName: Full=xPABPII-A;+++[PAB2B_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-B; Short=PABP-2-B; Short=Poly(A)-binding protein 2-B; AltName: Full=Nuclear poly(A)-binding protein 1-B; AltName: Full=Poly(A)-binding protein II-B; Short=PABII-B; AltName: Full=Polyadenylate-binding nuclear protein 1-B; AltName: Full=XLnPABP2-B; AltName: Full=nPABP2-B; AltName: Full=xPABPII-B;+++[PABP2_BOVIN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_HUMAN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_MOUSE|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_XENTR|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[S22AH_BOVIN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Lipocalin-2 receptor;+++[S22AH_HUMAN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor; AltName: Full=Neutrophil gelatinase-associated lipocalin receptor; Short=NgalR;+++[S22AH_MOUSE|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AH_RAT|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AV_HUMAN|diamond]RecName: Full=Putative solute carrier family 22 member 31 {ECO:0000305};"]
[100529097,"'RPL36A-HNRNPH2'",699.29,732.77,811.61,747.89,"03010///Ribosome","H00658///Syndromic X-linked mental retardation+++H00125///Fabry disease","M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes","R01329///Epimelibiose galactohydrolase Epimelibiose + H2O <=> D-Mannose + D-Galactose+++R03634///Stachyose + H2O <=> Raffinose + D-Galactose+++R05961///H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide+++R01194///3-O-alpha-D-Galactosyl-1D-myo-inositol galactohydrolase; 1-alpha-D-Galactosyl-myo-inositol alpha-D-Galactosyl-(1->3)-1D-myo-inositol + H2O <=> myo-Inositol + D-Galactose+++R04019///Digalactosylceramide galactohydrolase Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose+++R04470///Digalactosyl-diacylglycerol galactohydrolase Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose+++R05549///D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose+++R06091///Melibiose + H2O <=> D-Galactose + D-Glucose+++R01104///Galactosylglycerol galactohydrolase 3-beta-D-Galactosyl-sn-glycerol + H2O <=> D-Galactose + Glycerol+++R01101///melibiose galactohydrolase Melibiose + H2O <=> D-Galactose + D-Glucose+++R02926///Melibiitol galactohydrolase Melibiitol + H2O <=> D-Sorbitol + D-Galactose+++R01103///Raffinose galactohydrolase Raffinose + H2O <=> D-Galactose + Sucrose","GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005783///endoplasmic reticulum","GO:0003735///structural constituent of ribosome","GO:0006412///translation","RPL36A-HNRNPH2 readthrough","[H0Y3V9_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386974};+++[H7BZ11_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386655};"]
[100529144,"'CORO7-PAM16'",25.68,0,0,8.56,null,"H01830///Spondylometaphyseal dysplasia, Megarbane-Dagher-Melki type (SMDMDM)",null,null,"GO:0005794///Golgi apparatus","GO:0003779///actin binding","GO:0001503///ossification+++GO:0030150///protein import into mitochondrial matrix+++GO:0032780///negative regulation of ATPase activity+++GO:0030041///actin filament polymerization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","CORO7-PAM16 readthrough","[A0A0A6YYL4_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};+++[I3L167_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};"]
[100529240,"'ZNF816-ZNF321P'",7.14,9,7,7.71333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","ZNF816-ZNF321P readthrough","[ZN321_HUMAN|Reviewed]RecName: Full=Putative protein ZNF321; AltName: Full=Zinc finger protein 321 pseudogene;+++[A0A0X1KG74_HUMAN|Unreviewed]SubName: Full=ZNF816-ZNF321P readthrough {ECO:0000313|Ensembl:ENSP00000375656};"]
[100529241,"'HSPE1-MOB4'",0,0,8.9,2.96666666666667,"05152///Tuberculosis+++04940///Type I diabetes mellitus+++04212///Longevity regulating pathway - worm+++03018///RNA degradation+++05134///Legionellosis","H00679///Hypomyelinating leukodystrophy+++H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005737///cytoplasm","GO:0005524///ATP binding","GO:0006457///protein folding","HSPE1-MOB4 readthrough","[S4R3N1_HUMAN|Unreviewed]SubName: Full=HSPE1-MOB4 readthrough {ECO:0000313|Ensembl:ENSP00000474534};"]
[100529251,"'CKLF-CMTM1'",0,8.41,0,2.80333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005125///cytokine activity","GO:0006935///chemotaxis","CKLF-CMTM1 readthrough","[A0A087WVB3_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000479319};+++[A0A087X286_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000484781};+++[E9PIV8_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433857};+++[E9PLU7_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000435007}; SubName: Full=Chemokine-like factor {ECO:0000313|Ensembl:ENSP00000431270};+++[E9PSG2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433998};+++[H0YDF2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433503}; Flags: Fragment;"]
[100529261,"'CHURC1-FNTB'",0,17.07,0,5.69,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis",null,null,"R09844///farnesyl-diphosphate:protein-cysteine farnesyltransferase trans,trans-Farnesyl diphosphate + Protein-cysteine <=> S-Farnesyl protein + Diphosphate","GO:0005965///protein farnesyltransferase complex","GO:0004659///prenyltransferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004660///protein farnesyltransferase activity+++GO:0003824///catalytic activity+++GO:0008270///zinc ion binding","GO:0007275///multicellular organism development+++GO:0018343///protein farnesylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0018342///protein prenylation","CHURC1-FNTB readthrough","[FNTB_HUMAN|Reviewed]RecName: Full=Protein farnesyltransferase subunit beta; Short=FTase-beta; EC=2.5.1.58; AltName: Full=CAAX farnesyltransferase subunit beta; AltName: Full=Ras proteins prenyltransferase subunit beta;+++[B4DL54_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000447121}; SubName: Full=cDNA FLJ59570, highly similar to Protein farnesyltransferase subunit beta {ECO:0000313|EMBL:BAG59416.1};+++[H0YIM3_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000449668}; Flags: Fragment;+++[H0YIM9_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000449709}; Flags: Fragment;+++[H0YJ25_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000450692}; Flags: Fragment;"]
[10053,"'AP1M2'",15,18,18,17,"04142///Lysosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000139///Golgi membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0030131///clathrin adaptor complex+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006605///protein targeting+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0050690///regulation of defense response to virus by virus+++GO:0006886///intracellular protein transport+++GO:0006903///vesicle targeting+++GO:0015031///protein transport","adaptor related protein complex 1 subunit mu 2","[AP1M2_HUMAN|Reviewed]RecName: Full=AP-1 complex subunit mu-2; AltName: Full=AP-mu chain family member mu1B; AltName: Full=Adaptor protein complex AP-1 subunit mu-2; AltName: Full=Adaptor-related protein complex 1 subunit mu-2; AltName: Full=Clathrin assembly protein complex 1 mu-2 medium chain 2; AltName: Full=Golgi adaptor HA1/AP1 adaptin mu-2 subunit; AltName: Full=Mu-adaptin 2; AltName: Full=Mu1B-adaptin;+++[K7EJJ1_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465193}; Flags: Fragment;+++[K7EK69_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465488}; Flags: Fragment;+++[K7EL08_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465865}; Flags: Fragment;+++[K7EMG5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000466494}; Flags: Fragment;+++[K7EPI9_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467406};+++[K7EPR4_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467498}; Flags: Fragment;+++[K7ERH5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000468260}; Flags: Fragment;+++[Q53GI5_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 1, mu 2 subunit variant {ECO:0000313|EMBL:BAD96666.1}; Flags: Fragment;"]
[100532726,"'NDUFC2-KCTD14'",60.95,87.49,131.07,93.17,"00190///Oxidative phosphorylation+++01100///Metabolic pathways+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04714///Thermogenesis+++05010///Alzheimer's disease+++05016///Huntington's disease+++04723///Retrograde endocannabinoid signaling","H00810///Progressive myoclonic epilepsy (PME/ EPM)","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0070469///respiratory chain+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0055114///oxidation-reduction process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone","NDUFC2-KCTD14 readthrough","[NDUCR_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2; AltName: Full=NDUFC2-KCTD14 readthrough transcript protein;+++[A0A087WUM3_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000478766};+++[A0A087WY27_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000481472};+++[E9PRQ4_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000435967};"]
[100532731,"'COMMD3-BMI1'",210.09,149.39,203.8,187.76,"05206///MicroRNAs in cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer","H00025///Penile cancer",null,null,"GO:0016604///nuclear body+++GO:0035102///PRC1 complex+++GO:0005829///cytosol","GO:1990841///promoter-specific chromatin binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0006342///chromatin silencing+++GO:0006814///sodium ion transport","COMMD3-BMI1 readthrough","[BMI1_HUMAN|Reviewed]RecName: Full=Polycomb complex protein BMI-1; AltName: Full=Polycomb group RING finger protein 4; AltName: Full=RING finger protein 51;+++[Q5T8Z1_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000398759}; Flags: Fragment;+++[R4GMW6_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473382}; Flags: Fragment;+++[R4GMX3_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473391};+++[R4GN54_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473495}; Flags: Fragment;"]
[100533105,"'C8orf44-SGK3'",43.82,27.16,52.58,41.1866666666667,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0055037///recycling endosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0005737///cytoplasm+++GO:0005795///Golgi stack+++GO:0005654///nucleoplasm+++GO:0005769///early endosome","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0035091///phosphatidylinositol binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0016567///protein ubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0016320///endoplasmic reticulum membrane fusion+++GO:0090168///Golgi reassembly","C8orf44-SGK3 readthrough","[SGK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk3; EC=2.7.11.1; AltName: Full=Cytokine-independent survival kinase; AltName: Full=Serum/glucocorticoid-regulated kinase 3; AltName: Full=Serum/glucocorticoid-regulated kinase-like;+++[A0A024R807_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};"]
[100533106,"'ZHX1-C8orf76'",8.01,4.28,2.8,5.03,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","ZHX1-C8orf76 readthrough","[ZHX1R_HUMAN|Reviewed]RecName: Full=Zinc fingers and homeoboxes protein 1, isoform 2; AltName: Full=ZHX1-C8orf76 readthrough transcript protein;+++[A0A0X1KG80_HUMAN|Unreviewed]SubName: Full=Zinc fingers and homeoboxes protein 1, isoform 2 {ECO:0000313|Ensembl:ENSP00000481928}; Flags: Fragment;"]
[100533178,"'PRORY'",1,4,1,2,{"$nulls":7},"proline rich Y-linked","[PRORY_HUMAN|Reviewed]RecName: Full=Proline-rich protein, Y-linked;"]
[100533183,"'ZNF664-RFLNA'",47.78,44.84,12.32,34.98,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061181///regulation of chondrocyte development+++GO:0061572///actin filament bundle organization","ZNF664-RFLNA readthrough","[RFLA_HUMAN|Reviewed]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;"]
[100533467,"'BIVM-ERCC5'",602.96,452.4,407.2,487.52,"03420///Nucleotide excision repair","H00403///Disorders of nucleotide excision repair+++H01428///Xeroderma pigmentosum (XP)",null,null,"GO:0005634///nucleus","GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds","GO:0006281///DNA repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006295///nucleotide-excision repair, DNA incision, 3'-to lesion+++GO:0006289///nucleotide-excision repair","BIVM-ERCC5 readthrough","[A0A1W2PRR4_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492455}; Flags: Fragment;+++[A0A1W2PRU8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492444}; Flags: Fragment;+++[A0A1W2PS85_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492684};+++[Q59FZ7_HUMAN|Unreviewed]SubName: Full=DNA-repair protein complementing XP-G cells variant {ECO:0000313|EMBL:BAD92549.1}; Flags: Fragment;+++[R4GMW8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000491742}; SubName: Full=DNA repair protein-complementing XP-G cells {ECO:0000313|Ensembl:ENSP00000473384}; SubName: Full=ERCC5-202 protein {ECO:0000313|EMBL:CDY80175.1};"]
[100533496,"'TVP23C-CDRT4'",130.74,107.38,113.87,117.33,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009306///protein secretion+++GO:0016192///vesicle-mediated transport","TVP23C-CDRT4 readthrough","[TV23C_HUMAN|Reviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog C;+++[A0A0A6YYB9_HUMAN|Unreviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};+++[E5RGC5_HUMAN|Unreviewed]SubName: Full=Golgi apparatus membrane protein TVP23 homolog C {ECO:0000313|Ensembl:ENSP00000428748}; SubName: Full=TVP23C-CDRT4 readthrough {ECO:0000313|Ensembl:ENSP00000430143};"]
[100533952,"'RBAK-RBAKDN'",1.05,3.31,0,1.45333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","RBAK-RBAKDN readthrough","[A0A0A6YYG8_HUMAN|Unreviewed]SubName: Full=Protein RBAK-RBAKDN {ECO:0000313|Ensembl:ENSP00000380112};+++[I3L0D1_HUMAN|Unreviewed]SubName: Full=HCG1647537, isoform CRA_b {ECO:0000313|EMBL:EAW87320.1}; SubName: Full=RBAK-RBAKDN readthrough {ECO:0000313|Ensembl:ENSP00000385560};"]
[100534012,"'TNFAIP8L2-SCNM1'",11.28,10.43,0,7.23666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0019899///enzyme binding+++GO:0046872///metal ion binding","GO:0042981///regulation of apoptotic process+++GO:0050868///negative regulation of T cell activation+++GO:0050728///negative regulation of inflammatory response+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045087///innate immune response","TNFAIP8L2-SCNM1 readthrough","[SCNM1_HUMAN|Reviewed]RecName: Full=Sodium channel modifier 1;"]
[100534599,"'ISY1-RAB43'",392.69,496.23,404.32,431.08,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000974///Prp19 complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex+++GO:0032588///trans-Golgi network membrane+++GO:0071012///catalytic step 1 spliceosome+++GO:0071020///post-spliceosomal complex+++GO:0030670///phagocytic vesicle membrane+++GO:0045335///phagocytic vesicle+++GO:0070062///extracellular exosome","GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005525///GTP binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003924///GTPase activity+++GO:0046872///metal ion binding","GO:0000350///generation of catalytic spliceosome for second transesterification step","ISY1-RAB43 readthrough","[ISY1_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ISY1 homolog;+++[H9XFA1_HUMAN|Unreviewed]SubName: Full=ISY1-RAB43 {ECO:0000313|EMBL:AFG72967.1}; Flags: Fragment;"]
[10054,"'UBA2'",607,522,554,561,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0031510///SUMO activating enzyme complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0005524///ATP binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0016881///acid-amino acid ligase activity+++GO:0000166///nucleotide binding+++GO:0008047///enzyme activator activity+++GO:0019948///SUMO activating enzyme activity+++GO:0000287///magnesium ion binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0044388///small protein activating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0044241///lipid digestion+++GO:0072148///epithelial cell fate commitment+++GO:0007411///axon guidance+++GO:0021800///cerebral cortex tangential migration+++GO:0030154///cell differentiation+++GO:0001764///neuron migration+++GO:0021846///cell proliferation in forebrain+++GO:0007275///multicellular organism development+++GO:0046622///positive regulation of organ growth+++GO:0043085///positive regulation of catalytic activity+++GO:0021772///olfactory bulb development+++GO:0030900///forebrain development+++GO:0010628///positive regulation of gene expression+++GO:0021759///globus pallidus development+++GO:0016925///protein sumoylation+++GO:0007399///nervous system development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0021831///embryonic olfactory bulb interneuron precursor migration+++GO:0006355///regulation of transcription, DNA-templated","ubiquitin like modifier activating enzyme 2","[SAE2_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 2; EC=2.3.2.-; AltName: Full=Anthracycline-associated resistance ARX; AltName: Full=Ubiquitin-like 1-activating enzyme E1B; AltName: Full=Ubiquitin-like modifier-activating enzyme 2;+++[K7EPL2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000467433}; Flags: Fragment;+++[K7ES38_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468538};+++[K7ESK7_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468756}; Flags: Fragment;+++[U3KQ55_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475565};+++[U3KQ93_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475656};"]
[10055,"'SAE1'",1096,1133,1067,1098.66666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0031510///SUMO activating enzyme complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019948///SUMO activating enzyme activity+++GO:0043008///ATP-dependent protein binding+++GO:0044388///small protein activating enzyme binding+++GO:0008047///enzyme activator activity+++GO:0016874///ligase activity+++GO:0046982///protein heterodimerization activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0008022///protein C-terminus binding+++GO:0004839///ubiquitin activating enzyme activity","GO:0006464///cellular protein modification process+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0043085///positive regulation of catalytic activity","SUMO1 activating enzyme subunit 1","[SAE1_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 1; AltName: Full=Ubiquitin-like 1-activating enzyme E1A; Contains: RecName: Full=SUMO-activating enzyme subunit 1, N-terminally processed;+++[A0A024R0R4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_b {ECO:0000313|EMBL:EAW57462.1};+++[B3KNJ4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW57460.1}; SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000398818}; SubName: Full=cDNA FLJ14689 fis, clone NT2RP2005204, highly similar to Ubiquitin-like 1-activating enzyme E1A {ECO:0000313|EMBL:BAG51356.1};+++[M0QX65_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000468931}; Flags: Fragment;+++[M0QYM8_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469938}; Flags: Fragment;+++[M0QYP2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469978}; Flags: Fragment;+++[M0QZS6_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000470741};+++[M0R054_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000471010}; Flags: Fragment;+++[M0R286_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000472389}; Flags: Fragment;+++[M0R375_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000473037};"]
[10056,"'FARSB'",422,412.02,422,418.673333333333,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0016020///membrane+++GO:0009328///phenylalanine-tRNA ligase complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding+++GO:0004826///phenylalanine-tRNA ligase activity","GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0006412///translation+++GO:0051290///protein heterotetramerization","phenylalanyl-tRNA synthetase subunit beta","[SYFB_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase beta subunit; EC=6.1.1.20 {ECO:0000269|PubMed:20223217}; AltName: Full=Phenylalanyl-tRNA synthetase beta subunit; Short=PheRS;+++[Q9BR63_HUMAN|Unreviewed]SubName: Full=FARSB protein {ECO:0000313|EMBL:AAH06502.2}; Flags: Fragment;"]
[10057,"'ABCC5'",3524,2837,4103,3488,"01523///Antifolate resistance+++02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity","GO:0015711///organic anion transport+++GO:0055085///transmembrane transport+++GO:0030213///hyaluronan biosynthetic process+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport","ATP binding cassette subfamily C member 5","[MRP5_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 5; AltName: Full=ATP-binding cassette sub-family C member 5; AltName: Full=Multi-specific organic anion transporter C; Short=MOAT-C; AltName: Full=SMRP; AltName: Full=pABC11;+++[A5PKY6_HUMAN|Unreviewed]SubName: Full=ABCC5 protein {ECO:0000313|EMBL:AAI42671.1}; SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404809};+++[C9JZL5_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000399726}; Flags: Fragment;+++[E9PET4_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000390911};+++[F8WCY8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000403510};+++[F8WDH3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000409913};+++[H7C271_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404302}; Flags: Fragment;"]
[10058,"'ABCB6'",135,148,165,149.333333333333,"02010///ABC transporters","H00232///Hereditary stomatocytosis (HSt)+++H01027///Anophthalmia and microphthalmia (A/M)+++H02001///Familial pseudohyperkalemia",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005740///mitochondrial envelope+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005739///mitochondrion+++GO:0031307///integral component of mitochondrial outer membrane","GO:0015232///heme transporter activity+++GO:0020037///heme binding+++GO:0000166///nucleotide binding+++GO:0015562///efflux transmembrane transporter activity+++GO:0015439///heme-transporting ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0016887///ATPase activity","GO:0015886///heme transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007420///brain development+++GO:0055085///transmembrane transport+++GO:0043588///skin development+++GO:0006779///porphyrin-containing compound biosynthetic process","ATP binding cassette subfamily B member 6 (Langereis blood group)","[ABCB6_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family B member 6, mitochondrial; AltName: Full=Mitochondrial ABC transporter 3; Short=Mt-ABC transporter 3; AltName: Full=P-glycoprotein-related protein; AltName: Full=Ubiquitously-expressed mammalian ABC half transporter;+++[A0A024R436_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6, isoform CRA_f {ECO:0000313|EMBL:EAW70701.1};+++[A0A1D9ITY9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6 {ECO:0000313|EMBL:AOZ15555.1}; Flags: Fragment;+++[H7BXK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000295750}; Flags: Fragment;+++[H7C049_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000392988}; Flags: Fragment;+++[H7C1R6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000401811}; Flags: Fragment;+++[H7C245_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000404006}; Flags: Fragment;+++[H7C3Z0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000414646}; Flags: Fragment;+++[U3TD89_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91502.1}; Flags: Fragment;+++[U3TGG4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91501.2}; Flags: Fragment;+++[U3THN0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91500.2};+++[U3THP2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91503.1}; Flags: Fragment;+++[U3TJJ6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91499.1}; Flags: Fragment;+++[U3TJK0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91504.1}; Flags: Fragment;"]
[10059,"'DNM1L'",877.96,719,729.18,775.38,"04214///Apoptosis - fly+++04217///Necroptosis+++04668///TNF signaling pathway+++04621///NOD-like receptor signaling pathway+++04139///Mitophagy - yeast","H01900///Encephalopathy due to defective mitochondrial and peroxisomal fission","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R02918///L-Tyrosine:tRNA(Tyr) ligase (AMP-forming) ATP + L-Tyrosine + tRNA(Tyr) <=> AMP + Diphosphate + L-Tyrosyl-tRNA(Tyr)","GO:0045202///synapse+++GO:0099073///mitochondrion-derived vesicle+++GO:0098835///presynaptic endocytic zone membrane+++GO:0032991///protein-containing complex+++GO:0030672///synaptic vesicle membrane+++GO:0005874///microtubule+++GO:0031966///mitochondrial membrane+++GO:0030054///cell junction+++GO:0005777///peroxisome+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005905///clathrin-coated pit+++GO:0012505///endomembrane system+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0099503///secretory vesicle+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005903///brush border+++GO:0098794///postsynapse","GO:0003924///GTPase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0008289///lipid binding+++GO:0005525///GTP binding+++GO:0042803///protein homodimerization activity+++GO:0051433///BH2 domain binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0030276///clathrin binding+++GO:0008017///microtubule binding+++GO:0030742///GTP-dependent protein binding","GO:0012501///programmed cell death+++GO:0090141///positive regulation of mitochondrial fission+++GO:0043547///positive regulation of GTPase activity+++GO:0048488///synaptic vesicle endocytosis+++GO:0032459///regulation of protein oligomerization+++GO:0097194///execution phase of apoptosis+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:1904579///cellular response to thapsigargin+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0007005///mitochondrion organization+++GO:0090149///mitochondrial membrane fission+++GO:0070584///mitochondrion morphogenesis+++GO:0070585///protein localization to mitochondrion+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0036466///synaptic vesicle recycling via endosome+++GO:1990910///response to hypobaric hypoxia+++GO:0008637///apoptotic mitochondrial changes+++GO:1900063///regulation of peroxisome organization+++GO:0000266///mitochondrial fission+++GO:0048312///intracellular distribution of mitochondria+++GO:0061025///membrane fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0050714///positive regulation of protein secretion+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0016559///peroxisome fission+++GO:0060047///heart contraction+++GO:2000302///positive regulation of synaptic vesicle exocytosis+++GO:0007029///endoplasmic reticulum organization+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:0071396///cellular response to lipid+++GO:1905395///response to flavonoid+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0006897///endocytosis+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0051260///protein homooligomerization+++GO:0001836///release of cytochrome c from mitochondria+++GO:1903578///regulation of ATP metabolic process+++GO:0051259///protein complex oligomerization+++GO:0051289///protein homotetramerization+++GO:0070266///necroptotic process+++GO:0043065///positive regulation of apoptotic process","dynamin 1 like","[DNM1L_HUMAN|Reviewed]RecName: Full=Dynamin-1-like protein; EC=3.6.5.5; AltName: Full=Dnm1p/Vps1p-like protein; Short=DVLP; AltName: Full=Dynamin family member proline-rich carboxyl-terminal domain less; Short=Dymple; AltName: Full=Dynamin-like protein; AltName: Full=Dynamin-like protein 4; AltName: Full=Dynamin-like protein IV; Short=HdynIV; AltName: Full=Dynamin-related protein 1;+++[B4DDQ3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000396030}; SubName: Full=cDNA FLJ59840, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG56814.1};+++[B4DPZ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000390090}; SubName: Full=cDNA FLJ59948, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG60761.1};+++[B4DYR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56381, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG63828.1};+++[D3DUW5_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_c {ECO:0000313|EMBL:EAW88523.1};+++[D3DUW6_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_f {ECO:0000313|EMBL:EAW88527.1};+++[D3DUW7_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_a {ECO:0000313|EMBL:EAW88525.1};+++[F8VR28_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000450401};+++[F8VUJ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447845}; Flags: Fragment;+++[F8VYL3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448936};+++[F8VZ52_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447788}; Flags: Fragment;+++[F8W1W3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447013}; Flags: Fragment;+++[G8JLD5_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000350948};+++[H0YHY4_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448105}; Flags: Fragment;+++[H0YI79_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448802}; Flags: Fragment;+++[Q32Q67_HUMAN|Unreviewed]SubName: Full=DNM1L protein {ECO:0000313|EMBL:AAI07764.1}; Flags: Fragment;"]
[1006,"'CDH8'",315,304,176,265,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0043083///synaptic cleft+++GO:0097060///synaptic membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043679///axon terminus+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0016342///catenin complex","GO:0042802///identical protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding","GO:0007268///chemical synaptic transmission+++GO:0007043///cell-cell junction assembly+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0009409///response to cold+++GO:0050807///regulation of synapse organization+++GO:0035249///synaptic transmission, glutamatergic+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 8","[CADH8_HUMAN|Reviewed]RecName: Full=Cadherin-8; Flags: Precursor;+++[J3KRI5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462018};+++[J3KT81_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462847}; Flags: Fragment;+++[J3KTG8_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462976}; Flags: Fragment;+++[J3QKW5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463266};+++[J3QLE6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463511};+++[L8E7B0_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43150.1};+++[L8E8U5_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43151.1};+++[Q3LID3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla04261 {ECO:0000313|EMBL:BAE45735.1}; Flags: Fragment;+++[X6R3Y6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000299345};"]
[10060,"'ABCC9'",374.43,333.06,316.8,341.43,"02010///ABC transporters","H00294///Dilated cardiomyopathy (DCM)+++H00731///Atrial fibrillation",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0042383///sarcolemma+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0008282///inward rectifying potassium channel","GO:0044325///ion channel binding+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0015459///potassium channel regulator activity+++GO:0008281///sulfonylurea receptor activity+++GO:0005524///ATP binding+++GO:0005267///potassium channel activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005215///transporter activity","GO:1990573///potassium ion import across plasma membrane+++GO:0055085///transmembrane transport+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0006813///potassium ion transport+++GO:0051607///defense response to virus+++GO:0042493///response to drug","ATP binding cassette subfamily C member 9","[ABCC9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family C member 9; AltName: Full=Sulfonylurea receptor 2;+++[A0A024RAV7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW96456.1};+++[G3V1N6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000442604}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_a {ECO:0000313|EMBL:EAW96452.1};+++[H0YFV4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000440521}; Flags: Fragment;+++[K4DI86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_e {ECO:0000313|EMBL:EAW96458.1};+++[Q8N4N7_HUMAN|Unreviewed]SubName: Full=ABCC9 protein {ECO:0000313|EMBL:AAH33804.1}; SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000317518};"]
[10061,"'ABCF2'",1287,1284,1229,1266.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005740///mitochondrial envelope+++GO:0000786///nucleosome+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0005215///transporter activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity",null,"ATP binding cassette subfamily F member 2","[ABCF2_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family F member 2; AltName: Full=Iron-inhibited ABC transporter 2;+++[A0A090N7X1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24508.1};+++[A0A090N7Y2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24507.1};+++[C9JHK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000395785}; Flags: Fragment;+++[C9JZV3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000419720}; Flags: Fragment;+++[L0R4T3_HUMAN|Unreviewed]RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};"]
[10062,"'NR1H3'",37,78,77,64,"03320///PPAR signaling pathway+++05160///Hepatitis C+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease (NAFLD)",{"$nulls":3},"GO:0005634///nucleus+++GO:0043235///receptor complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0004879///nuclear receptor activity+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0038023///signaling receptor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003713///transcription coactivator activity+++GO:0015485///cholesterol binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0032810///sterol response element binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity","GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010887///negative regulation of cholesterol storage+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0090341///negative regulation of secretion of lysosomal enzymes+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0050728///negative regulation of inflammatory response+++GO:0042632///cholesterol homeostasis+++GO:2000325///regulation of nuclear receptor transcription coactivator activity+++GO:0055092///sterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0055088///lipid homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0048550///negative regulation of pinocytosis+++GO:0043031///negative regulation of macrophage activation+++GO:0045861///negative regulation of proteolysis+++GO:0010875///positive regulation of cholesterol efflux+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032570///response to progesterone+++GO:0043277///apoptotic cell clearance+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032369///negative regulation of lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0070328///triglyceride homeostasis+++GO:0044255///cellular lipid metabolic process","nuclear receptor subfamily 1 group H member 3","[NR1H3_HUMAN|Reviewed]RecName: Full=Oxysterols receptor LXR-alpha; AltName: Full=Liver X receptor alpha; AltName: Full=Nuclear receptor subfamily 1 group H member 3;+++[B4DXU5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56172, highly similar to Oxysterols receptor LXR-alpha {ECO:0000313|EMBL:BAG63507.1};+++[B5MBY7_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000385073};+++[B6ZGS8_HUMAN|Unreviewed]SubName: Full=Liver X receptor alpha {ECO:0000313|EMBL:BAH02289.1};+++[C9J2C8_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000412636}; Flags: Fragment;+++[C9J4R0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000391005}; Flags: Fragment;+++[C9JBS2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403696}; Flags: Fragment;+++[C9JCS0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000415591}; Flags: Fragment;+++[C9JEC2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000396132}; Flags: Fragment;+++[C9JJ16_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403798}; Flags: Fragment;+++[C9JTS4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000413095}; Flags: Fragment;+++[E9PID2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000432073};+++[E9PLL4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000433271};+++[E9PPA1_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000434650}; Flags: Fragment;+++[F1D8N1_HUMAN|Unreviewed]SubName: Full=Liver X nuclear receptor alpha variant 1 {ECO:0000313|EMBL:ADZ17330.1};+++[F8WC63_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000406692};+++[F8WEY6_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000407716};"]
[10063,"'COX17'",136,199,155,163.333333333333,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00154///Cytochrome c oxidase",null,"GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0016531///copper chaperone activity+++GO:0046872///metal ion binding+++GO:0005507///copper ion binding+++GO:1903136///cuprous ion binding+++GO:0005515///protein binding","GO:1904960///positive regulation of cytochrome-c oxidase activity+++GO:0006825///copper ion transport+++GO:0006091///generation of precursor metabolites and energy+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation","cytochrome c oxidase copper chaperone COX17","[COX17_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase copper chaperone;+++[C9J8T6_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417651}; SubName: Full=HCG2022684, isoform CRA_b {ECO:0000313|EMBL:EAW79546.1};+++[H7C4E5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417120}; Flags: Fragment;+++[H7C5P5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000420406}; Flags: Fragment;"]
[100631383,"'FAM47E-STBD1'",48.52,15.42,34.41,32.7833333333333,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"FAM47E-STBD1 readthrough","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[D6RA91_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000423044}; Flags: Fragment;+++[F6W5V1_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000425528};"]
[100652748,"'TIMM23B'",140.42,141.25,137.16,139.61,"04212///Longevity regulating pathway - worm",{"$nulls":3},"GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005575///cellular_component+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0008320///protein transmembrane transporter activity","GO:0006886///intracellular protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0008150///biological_process+++GO:0015031///protein transport","translocase of inner mitochondrial membrane 23 homolog B","[TI23B_HUMAN|Reviewed]RecName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B;+++[B4DDK6_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000389331}; SubName: Full=cDNA FLJ60010, moderately similar to Mitochondrial import inner membrane translocase subunit Tim23 {ECO:0000313|EMBL:BAG56767.1};+++[M0QZG8_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000470535};+++[S4R2X5_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000473724};"]
[100652824,"'KIAA2012'",0,1,2,1,"05225///Hepatocellular carcinoma+++04390///Hippo signaling pathway+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04150///mTOR signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05166///HTLV-I infection+++05165///Human papillomavirus infection+++04916///Melanogenesis+++04310///Wnt signaling pathway+++05224///Breast cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer","H00048///Hepatocellular carcinoma+++H00031///Breast cancer","M00677///Wnt signaling",null,"GO:0055038///recycling endosome membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0030165///PDZ domain binding+++GO:0042813///Wnt-activated receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017147///Wnt-protein binding+++GO:0005109///frizzled binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding","GO:0033077///T cell differentiation in thymus+++GO:0019827///stem cell population maintenance+++GO:0048103///somatic stem cell division+++GO:0030182///neuron differentiation+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0042327///positive regulation of phosphorylation+++GO:0060231///mesenchymal to epithelial transition+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0046330///positive regulation of JNK cascade+++GO:2000726///negative regulation of cardiac muscle cell differentiation+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0071300///cellular response to retinoic acid+++GO:0060070///canonical Wnt signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0042666///negative regulation of ectodermal cell fate specification","KIAA2012","[K2012_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA2012 {ECO:0000305};+++[A0A1B0GV91_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000490419}; Flags: Fragment;+++[H7C5G6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000419834};"]
[100652901,"'LOC100652901'",30,10,15,18.3333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0010494///cytoplasmic stress granule","GO:0003727///single-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding","GO:0032197///transposition, RNA-mediated","uncharacterized LOC100652901","[Q6ZNX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26942 fis, clone RCT07464 {ECO:0000313|EMBL:BAC85354.1};"]
[100653515,"'CEP295NL'",9,5,2,5.33333333333333,{"$nulls":4},"GO:0005929///cilium+++GO:0042995///cell projection","GO:0008191///metalloendopeptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity","CEP295 N-terminal like","[C295L_HUMAN|Reviewed]RecName: Full=CEP295 N-terminal-like protein {ECO:0000305}; AltName: Full=KIAA1731 N-terminal like protein {ECO:0000312|HGNC:HGNC:44659};+++[K7EL90_HUMAN|Unreviewed]SubName: Full=CEP295 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000465968}; Flags: Fragment;"]
[10066,"'SCAMP2'",2458,2690,2454,2534,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0055038///recycling endosome membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0032588///trans-Golgi network membrane+++GO:0030133///transport vesicle","GO:0005515///protein binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","secretory carrier membrane protein 2","[SCAM2_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 2; Short=Secretory carrier membrane protein 2;+++[A0A140VK92_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[A8K769_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BMN2_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BN93_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BPL9_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BQW2_HUMAN|Unreviewed]SubName: Full=Secretory carrier-associated membrane protein 2 {ECO:0000313|Ensembl:ENSP00000455963};+++[H3BUB6_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BV04_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[Q6IBK3_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};"]
[10067,"'SCAMP3'",2392,2429,2534,2451.66666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032588///trans-Golgi network membrane","GO:0031625///ubiquitin protein ligase binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","secretory carrier membrane protein 3","[SCAM3_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 3; Short=Secretory carrier membrane protein 3;+++[Q6FHJ5_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;"]
[10068,"'IL18BP'",92,69,73,78,{"$nulls":4},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0042007///interleukin-18 binding+++GO:0048019///receptor antagonist activity","GO:0070301///cellular response to hydrogen peroxide+++GO:0032496///response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor+++GO:0042088///T-helper 1 type immune response+++GO:0071345///cellular response to cytokine stimulus+++GO:1900116///extracellular negative regulation of signal transduction+++GO:0035655///interleukin-18-mediated signaling pathway","interleukin 18 binding protein","[I18BP_HUMAN|Reviewed]RecName: Full=Interleukin-18-binding protein; Short=IL-18BP; AltName: Full=Tadekinig-alfa; Flags: Precursor;+++[A0A024R5G2_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_d {ECO:0000313|EMBL:EAW74817.1};+++[A0A024R5I1_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_c {ECO:0000313|EMBL:EAW74820.1};+++[A0A024R5M7_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_b {ECO:0000313|EMBL:EAW74819.1};+++[G3V1C5_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW74812.1}; SubName: Full=Interleukin-18-binding protein {ECO:0000313|Ensembl:ENSP00000434717};"]
[10069,"'RWDD2B'",171,171,159,167,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","RWD domain containing 2B","[RWD2B_HUMAN|Reviewed]RecName: Full=RWD domain-containing protein 2B;"]
[10071,"'MUC12'",14,7,8,9.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0001558///regulation of cell growth+++GO:0016266///O-glycan processing+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","mucin 12, cell surface associated","[MUC12_HUMAN|Reviewed]RecName: Full=Mucin-12; Short=MUC-12; AltName: Full=Mucin-11; Short=MUC-11; Flags: Precursor;+++[A1L198_HUMAN|Unreviewed]SubName: Full=MUC12 protein {ECO:0000313|EMBL:AAI27878.1}; Flags: Fragment;+++[H7BXN1_HUMAN|Unreviewed]SubName: Full=Mucin-12 {ECO:0000313|Ensembl:ENSP00000306919}; Flags: Fragment;+++[L8E898_HUMAN|Unreviewed]SubName: Full=Alternative protein MUC12 {ECO:0000313|EMBL:CCQ42956.1};"]
[10072,"'DPP3'",1015,1069,985,1023,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016607///nuclear speck","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004177///aminopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008237///metallopeptidase activity+++GO:0008239///dipeptidyl-peptidase activity","GO:0006508///proteolysis","dipeptidyl peptidase 3","[DPP3_HUMAN|Reviewed]RecName: Full=Dipeptidyl peptidase 3; EC=3.4.14.4 {ECO:0000269|PubMed:11209758, ECO:0000269|PubMed:1515063, ECO:0000269|PubMed:3233187, ECO:0000269|PubMed:9425109}; AltName: Full=Dipeptidyl aminopeptidase III; AltName: Full=Dipeptidyl arylamidase III; AltName: Full=Dipeptidyl peptidase III; Short=DPP III; AltName: Full=Enkephalinase B;+++[E9PKK8_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000431606}; Flags: Fragment;+++[E9PNX5_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000437101}; Flags: Fragment;+++[E9PPK9_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000432618}; Flags: Fragment;+++[E9PQ14_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000434518}; Flags: Fragment;+++[E9PQF2_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000436820}; Flags: Fragment;+++[G3V180_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[G3V1D3_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[Q5JPB8_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};"]
[10073,"'SNUPN'",129,145,132,135.333333333333,"03013///RNA transport",{"$nulls":3},"GO:0005829///cytosol+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0061608///nuclear import signal receptor activity+++GO:0005515///protein binding","GO:0006606///protein import into nucleus+++GO:0061015///snRNA import into nucleus+++GO:0000387///spliceosomal snRNP assembly+++GO:0051170///import into nucleus","snurportin 1","[SPN1_HUMAN|Reviewed]RecName: Full=Snurportin-1; AltName: Full=RNA U transporter 1;+++[H3BQR0_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000455894}; Flags: Fragment;+++[H3BRI5_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456260}; Flags: Fragment;+++[H3BSK1_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456742}; Flags: Fragment;+++[H3BTA6_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457093}; Flags: Fragment;+++[H3BUB4_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457562}; Flags: Fragment;"]
[10075,"'HUWE1'",8149,6232,7675,7352,"04120///Ubiquitin mediated proteolysis","H00658///Syndromic X-linked mental retardation",null,null,"GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0003723///RNA binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006281///DNA repair+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0043312///neutrophil degranulation+++GO:0006284///base-excision repair+++GO:0000209///protein polyubiquitination+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016574///histone ubiquitination","HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase","[HUWE1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase HUWE1; EC=2.3.2.26; AltName: Full=ARF-binding protein 1; Short=ARF-BP1; AltName: Full=HECT, UBA and WWE domain-containing protein 1; AltName: Full=HECT-type E3 ubiquitin transferase HUWE1; AltName: Full=Homologous to E6AP carboxyl terminus homologous protein 9; Short=HectH9; AltName: Full=Large structure of UREB1; Short=LASU1; AltName: Full=Mcl-1 ubiquitin ligase E3; Short=Mule; AltName: Full=Upstream regulatory element-binding protein 1; Short=URE-B1; Short=URE-binding protein 1;+++[A0A024R9U8_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW93163.1};+++[A0A024R9W5_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW93166.1};+++[A0A024R9Y3_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW93165.1};+++[A0A087X146_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000483891}; Flags: Fragment;+++[A0A087X1S3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000484417}; Flags: Fragment;+++[A0A1B0GXC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000413651}; Flags: Fragment;+++[H0Y659_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000403236}; Flags: Fragment;+++[L8E996_HUMAN|Unreviewed]SubName: Full=Alternative protein HUWE1 {ECO:0000313|EMBL:CCQ43744.1};+++[Q3B7K0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAI07577.1}; Flags: Fragment;+++[Q5H924_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42656.1}; Flags: Fragment;+++[Q5H935_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42644.1}; Flags: Fragment;+++[Q5H962_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42353.1};+++[Q5H963_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42352.1}; Flags: Fragment;+++[Q5H964_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42351.1}; Flags: Fragment;+++[Q8IWJ0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAH38184.1}; Flags: Fragment;"]
[10076,"'PTPRU'",3538,3615,3142,3431.66666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:0030027///lamellipodium+++GO:0098978///glutamatergic synapse+++GO:0005911///cell-cell junction+++GO:0099061///integral component of postsynaptic density membrane+++GO:0016324///apical plasma membrane+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0098982///GABA-ergic synapse+++GO:0030426///growth cone+++GO:0005887///integral component of plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0008013///beta-catenin binding+++GO:0017147///Wnt-protein binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0016787///hydrolase activity","GO:0034109///homotypic cell-cell adhesion+++GO:0016311///dephosphorylation+++GO:0031100///animal organ regeneration+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0007185///transmembrane receptor protein tyrosine phosphatase signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0032835///glomerulus development+++GO:0002548///monocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0034394///protein localization to cell surface+++GO:0007155///cell adhesion+++GO:0050807///regulation of synapse organization+++GO:0006470///protein dephosphorylation+++GO:0030154///cell differentiation+++GO:0010977///negative regulation of neuron projection development+++GO:0030032///lamellipodium assembly+++GO:0007411///axon guidance+++GO:0030336///negative regulation of cell migration+++GO:0090260///negative regulation of retinal ganglion cell axon guidance+++GO:0003105///negative regulation of glomerular filtration+++GO:0003093///regulation of glomerular filtration+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0008285///negative regulation of cell proliferation+++GO:0036060///slit diaphragm assembly","protein tyrosine phosphatase, receptor type U","[PTPRU_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase U; Short=R-PTP-U; EC=3.1.3.48; AltName: Full=Pancreatic carcinoma phosphatase 2; Short=PCP-2; AltName: Full=Protein-tyrosine phosphatase J; Short=PTP-J; Short=hPTP-J; AltName: Full=Protein-tyrosine phosphatase pi; Short=PTP pi; AltName: Full=Protein-tyrosine phosphatase receptor omicron; Short=PTP-RO; AltName: Full=Receptor-type protein-tyrosine phosphatase psi; Short=R-PTP-psi; Flags: Precursor;+++[H0YH11_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[H0YH60_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[L8ECC6_HUMAN|Unreviewed]SubName: Full=Alternative protein PTPRU {ECO:0000313|EMBL:CCQ43332.1};+++[Q9P0U2_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase {ECO:0000313|EMBL:AAF67472.1};"]
[10077,"'TSPAN32'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0070442///integrin alphaIIb-beta3 complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0009986///cell surface+++GO:0031225///anchored component of membrane+++GO:0016020///membrane+++GO:0033017///sarcoplasmic reticulum membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003674///molecular_function","GO:0007010///cytoskeleton organization+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007599///hemostasis+++GO:0006471///protein ADP-ribosylation+++GO:0007596///blood coagulation+++GO:0070527///platelet aggregation+++GO:0007267///cell-cell signaling+++GO:0042832///defense response to protozoan+++GO:0008285///negative regulation of cell proliferation+++GO:0018120///peptidyl-arginine ADP-ribosylation+++GO:0050688///regulation of defense response to virus","tetraspanin 32","[TSN32_HUMAN|Reviewed]RecName: Full=Tetraspanin-32; Short=Tspan-32; AltName: Full=Protein Phemx;+++[D3YTD1_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000405205};+++[F8WB10_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000405001};+++[F8WCN6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000343285};+++[G3XAG6_HUMAN|Unreviewed]SubName: Full=Tetraspanin 32, isoform CRA_e {ECO:0000313|EMBL:EAX02502.1}; SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000370509}; Flags: Fragment;+++[Q7Z5M9_HUMAN|Unreviewed]SubName: Full=Pan-hematopoietic expression protein {ECO:0000313|EMBL:AAP76185.1};"]
[10078,"'TSSC4'",380,407,333,373.333333333333,{"$nulls":5},"GO:0005515///protein binding",null,"tumor suppressing subtransferable candidate 4","[TSSC4_HUMAN|Reviewed]RecName: Full=Protein TSSC4; AltName: Full=Tumor-suppressing STF cDNA 4 protein; AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein;+++[A0A024RCB9_HUMAN|Unreviewed]SubName: Full=Tumor suppressing subtransferable candidate 4, isoform CRA_a {ECO:0000313|EMBL:EAX02513.1};+++[A6NCC9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000370380};+++[C9JDU0_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000403475}; Flags: Fragment;+++[C9JHT9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000396925}; Flags: Fragment;+++[C9JJV1_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000416937}; Flags: Fragment;+++[E9PL88_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000431430}; Flags: Fragment;+++[E9PME3_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000435013}; Flags: Fragment;"]
[10079,"'ATP9A'",776,626,713,705,null,"H00624///Familial cholestasis",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005769///early endosome+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding","GO:0006897///endocytosis+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport","ATPase phospholipid transporting 9A (putative)","[ATP9A_HUMAN|Reviewed]RecName: Full=Probable phospholipid-transporting ATPase IIA; EC=3.6.3.1; AltName: Full=ATPase class II type 9A;+++[A0A0A0MR22_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[B4DR18_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[Q2NLD0_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033}; Flags: Fragment;+++[Q96B35_HUMAN|Unreviewed]SubName: Full=ATP9A protein {ECO:0000313|EMBL:AAH16044.1}; Flags: Fragment;"]
[1008,"'CDH10'",281,225,226,244,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099059///integral component of presynaptic active zone membrane+++GO:0016342///catenin complex+++GO:0098982///GABA-ergic synapse+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0099060///integral component of postsynaptic specialization membrane","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 10","[CAD10_HUMAN|Reviewed]RecName: Full=Cadherin-10; AltName: Full=T2-cadherin; Flags: Precursor;+++[D6RJG0_HUMAN|Unreviewed]SubName: Full=Cadherin-10 {ECO:0000313|Ensembl:ENSP00000425653};+++[L8ECD4_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH10 {ECO:0000313|EMBL:CCQ43372.1};+++[X5D8X5_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform A {ECO:0000313|EMBL:AHW56448.1}; SubName: Full=Cadherin 10, type 2 (T2-cadherin) {ECO:0000313|EMBL:EAX10742.1}; Flags: Fragment;+++[X5DNG6_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform B {ECO:0000313|EMBL:AHW56446.1}; Flags: Fragment;+++[X5DQT8_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform C {ECO:0000313|EMBL:AHW56447.1}; Flags: Fragment;"]
[10081,"'PDCD7'",222,275,228,241.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005689///U12-type spliceosomal complex",null,"GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0051384///response to glucocorticoid+++GO:0000398///mRNA splicing, via spliceosome","programmed cell death 7","[PDCD7_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 7; AltName: Full=ES18; Short=hES18;+++[A3KMF9_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAI31705.1}; Flags: Fragment;+++[H3BT73_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 7 {ECO:0000313|Ensembl:ENSP00000457053}; Flags: Fragment;+++[Q569I4_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAH92464.1}; Flags: Fragment;+++[Q6IEG3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 7, isoform CRA_a {ECO:0000313|EMBL:EAW77713.1}; SubName: Full=U11/U12 snRNP 59K {ECO:0000313|EMBL:DAA05494.1};"]
[10082,"'GPC6'",2186,1521,1471,1726,null,"H02154///Omodysplasia+++H00493///Heparan sulfate proteoglycan gene defects",null,null,"GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0005634///nucleus+++GO:0062023///collagen-containing extracellular matrix+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0046658///anchored component of plasma membrane+++GO:0043202///lysosomal lumen+++GO:0005796///Golgi lumen+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding+++GO:1904929///coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway","GO:0006027///glycosaminoglycan catabolic process+++GO:0001523///retinoid metabolic process+++GO:0016477///cell migration+++GO:0009966///regulation of signal transduction+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane","glypican 6","[GPC6_HUMAN|Reviewed]RecName: Full=Glypican-6; Contains: RecName: Full=Secreted glypican-6; Flags: Precursor;+++[A0A087WT82_HUMAN|Unreviewed]SubName: Full=Glypican-6 {ECO:0000313|Ensembl:ENSP00000477667};"]
[100820829,"'MYZAP'",5.27,12.91,8,8.72666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0030018///Z disc","GO:0005515///protein binding","GO:0035556///intracellular signal transduction","myocardial zonula adherens protein","[MYZAP_HUMAN|Reviewed]RecName: Full=Myocardial zonula adherens protein; AltName: Full=GRINL1A upstream protein; Short=Gup; Flags: Precursor;+++[A0A024R5W4_HUMAN|Unreviewed]SubName: Full=HCG40688, isoform CRA_a {ECO:0000313|EMBL:EAW77523.1};+++[H0YCD3_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000431396}; Flags: Fragment;+++[H3BTD5_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000457126}; Flags: Fragment;"]
[10083,"'USH1C'",2,1,0,1,null,"H00605///Deafness, autosomal recessive+++H00779///Usher syndrome (US)",null,null,"GO:0002142///stereocilia ankle link complex+++GO:0045202///synapse+++GO:0005903///brush border+++GO:0005902///microvillus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0032420///stereocilium+++GO:0005886///plasma membrane+++GO:0001917///photoreceptor inner segment+++GO:0032391///photoreceptor connecting cilium+++GO:0005737///cytoplasm+++GO:0001750///photoreceptor outer segment+++GO:0002141///stereocilia ankle link+++GO:0032426///stereocilium tip","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0030507///spectrin binding","GO:0034622///cellular protein-containing complex assembly+++GO:0050953///sensory perception of light stimulus+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0042472///inner ear morphogenesis+++GO:1904106///protein localization to microvillus+++GO:0045494///photoreceptor cell maintenance+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0030046///parallel actin filament bundle assembly+++GO:0007605///sensory perception of sound+++GO:1904970///brush border assembly+++GO:0032532///regulation of microvillus length+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0050957///equilibrioception+++GO:0051017///actin filament bundle assembly+++GO:0030154///cell differentiation","USH1 protein network component harmonin","[USH1C_HUMAN|Reviewed]RecName: Full=Harmonin; AltName: Full=Antigen NY-CO-38/NY-CO-37; AltName: Full=Autoimmune enteropathy-related antigen AIE-75; AltName: Full=Protein PDZ-73; AltName: Full=Renal carcinoma antigen NY-REN-3; AltName: Full=Usher syndrome type-1C protein;+++[A0A0S2Z4U9_HUMAN|Unreviewed]SubName: Full=Usher syndrome 1C (Autosomal recessive, severe), isoform CRA_d {ECO:0000313|EMBL:EAW68434.1}; SubName: Full=Usher syndrome 1C isoform 2 {ECO:0000313|EMBL:ALQ33957.1}; Flags: Fragment;+++[A0A0S2Z4V1_HUMAN|Unreviewed]SubName: Full=Usher syndrome 1C (Autosomal recessive, severe), isoform CRA_a {ECO:0000313|EMBL:EAW68431.1}; SubName: Full=Usher syndrome 1C isoform 1 {ECO:0000313|EMBL:ALQ33956.1}; Flags: Fragment;+++[E9PNW1_HUMAN|Unreviewed]SubName: Full=Harmonin {ECO:0000313|Ensembl:ENSP00000437128}; Flags: Fragment;"]
[10084,"'PQBP1'",471,528,484,494.333333333333,"03040///Spliceosome","H01913///Renpenning syndrome+++H00480///Non-syndromic X-linked mental retardation","M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0010494///cytoplasmic stress granule+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071598///neuronal ribonucleoprotein granule","GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043021///ribonucleoprotein complex binding","GO:0006355///regulation of transcription, DNA-templated+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0032481///positive regulation of type I interferon production+++GO:0031175///neuron projection development+++GO:0002218///activation of innate immune response+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071360///cellular response to exogenous dsRNA+++GO:0002230///positive regulation of defense response to virus by host+++GO:0008380///RNA splicing+++GO:0051607///defense response to virus+++GO:0043484///regulation of RNA splicing+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0048814///regulation of dendrite morphogenesis","polyglutamine binding protein 1","[PQBP1_HUMAN|Reviewed]RecName: Full=Polyglutamine-binding protein 1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; Short=PQBP-1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; AltName: Full=38 kDa nuclear protein containing a WW domain {ECO:0000303|PubMed:10198427}; Short=Npw38 {ECO:0000303|PubMed:10198427}; AltName: Full=Polyglutamine tract-binding protein 1 {ECO:0000303|PubMed:10332029};+++[A0A0S2Z4V5_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33958.1}; SubName: Full=Polyglutamine binding protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW50737.1}; Flags: Fragment;+++[A0A0S2Z556_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33959.1}; Flags: Fragment;+++[H7C053_HUMAN|Unreviewed]SubName: Full=Polyglutamine-binding protein 1 {ECO:0000313|Ensembl:ENSP00000393013}; Flags: Fragment;+++[Q4VY28_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein variant 12 {ECO:0000313|EMBL:CAJ00551.1}; Flags: Fragment;"]
[10085,"'EDIL3'",5176,3816,3724,4238.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:1903561///extracellular vesicle","GO:0005201///extracellular matrix structural constituent+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0010811///positive regulation of cell-substrate adhesion","EGF like repeats and discoidin domains 3","[EDIL3_HUMAN|Reviewed]RecName: Full=EGF-like repeat and discoidin I-like domain-containing protein 3; AltName: Full=Developmentally-regulated endothelial cell locus 1 protein; AltName: Full=Integrin-binding protein DEL1; Flags: Precursor;"]
[10086,"'HHLA1'",1,0,0,0.333333333333333,"04725///Cholinergic synapse","H00806///Benign familial neonatal and infantile epilepsies",null,null,"GO:0005576///extracellular region","GO:0005516///calmodulin binding+++GO:0005249///voltage-gated potassium channel activity","GO:0034765///regulation of ion transmembrane transport+++GO:0007268///chemical synaptic transmission+++GO:0060081///membrane hyperpolarization+++GO:0071805///potassium ion transmembrane transport","HERV-H LTR-associating 1","[HHLA1_HUMAN|Reviewed]RecName: Full=HERV-H LTR-associating protein 1; Flags: Precursor;+++[C9JY47_HUMAN|Unreviewed]SubName: Full=HERV-H LTR-associating protein 1 {ECO:0000313|Ensembl:ENSP00000407107};"]
[100861412,"'FSBP'",43.31,28.51,29.97,33.93,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","fibrinogen silencer binding protein","[FSBP_HUMAN|Reviewed]RecName: Full=Fibrinogen silencer-binding protein;+++[J3KSW4_HUMAN|Unreviewed]SubName: Full=Fibrinogen silencer-binding protein {ECO:0000313|Ensembl:ENSP00000462684};"]
[100862671,"'TMEM265'",92,95,120,102.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009607///response to biotic stimulus","transmembrane protein 265","[TM265_HUMAN|Reviewed]RecName: Full=Transmembrane protein 265 {ECO:0000312|HGNC:HGNC:51241};"]
[10087,"'COL4A3BP'",656.3,376,488,506.766666666667,"05202///Transcriptional misregulation in cancer+++05213///Endometrial cancer+++05224///Breast cancer+++04140///Autophagy - animal+++05210///Colorectal cancer+++05220///Chronic myeloid leukemia+++05212///Pancreatic cancer+++05214///Glioma+++05216///Thyroid cancer+++04137///Mitophagy - animal+++05218///Melanoma+++05217///Basal cell carcinoma+++03460///Fanconi anemia pathway+++05226///Gastric cancer+++05225///Hepatocellular carcinoma+++05222///Small cell lung cancer+++05200///Pathways in cancer+++05223///Non-small cell lung cancer","H00773///Autosomal dominant mental retardation",null,null,"GO:0005581///collagen trimer+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005623///cell+++GO:0048471///perinuclear region of cytoplasm","GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0120017///intermembrane ceramide transfer activity+++GO:0008289///lipid binding+++GO:1902388///ceramide 1-phosphate transporter activity+++GO:0016301///kinase activity+++GO:1902387///ceramide 1-phosphate binding+++GO:0097001///ceramide binding+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0006869///lipid transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0003007///heart morphogenesis+++GO:0055088///lipid homeostasis+++GO:0001701///in utero embryonic development+++GO:0008283///cell proliferation+++GO:0006672///ceramide metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0120009///intermembrane lipid transfer+++GO:0007029///endoplasmic reticulum organization+++GO:0120012///intermembrane sphingolipid transfer+++GO:0035621///ER to Golgi ceramide transport+++GO:0035627///ceramide transport+++GO:0000902///cell morphogenesis+++GO:1902389///ceramide 1-phosphate transport+++GO:0070584///mitochondrion morphogenesis+++GO:0006936///muscle contraction+++GO:0007165///signal transduction+++GO:0006955///immune response","collagen type IV alpha 3 binding protein","[C43BP_HUMAN|Reviewed]RecName: Full=Collagen type IV alpha-3-binding protein; AltName: Full=Ceramide transfer protein {ECO:0000303|PubMed:14685229}; Short=hCERT; AltName: Full=Goodpasture antigen-binding protein; Short=GPBP; AltName: Full=START domain-containing protein 11; Short=StARD11; AltName: Full=StAR-related lipid transfer protein 11;+++[A0A024RAJ5_HUMAN|Unreviewed]SubName: Full=Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW95758.1};+++[A0A0A0MRE4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000350046}; Flags: Fragment;+++[A0A2R8Y3S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493565}; Flags: Fragment;+++[A0A2R8Y5G0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494760}; Flags: Fragment;+++[A0A2R8Y5H3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494810}; Flags: Fragment;+++[A0A2R8Y5S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494804};+++[A0A2R8Y773_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495798}; Flags: Fragment;+++[A0A2R8Y7C5_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496016};+++[A0A2R8Y7Q9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496462};+++[A0A2R8YCI0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493604};+++[A0A2R8YDX6_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495038}; Flags: Fragment;+++[A0A2R8YE18_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495172};+++[A0A2R8YE59_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494073}; Flags: Fragment;+++[A0A2R8YEA4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495430};+++[A0A2R8YEK8_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494424};+++[A0A2R8YFA1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494969}; Flags: Fragment;+++[A0A2R8YFI2_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496472};+++[A0A2U3TZL3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000369862}; Flags: Fragment;+++[H0Y9J1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000424244}; Flags: Fragment;"]
[100873985,"'MED14OS'",0,1,0,0.333333333333333,{"$nulls":7},"MED14 opposite strand","[M14OS_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein MED14OS {ECO:0000305}; AltName: Full=MED14 antisense gene protein 1 {ECO:0000305}; AltName: Full=MED14 opposite strand protein {ECO:0000312|HGNC:HGNC:40162};"]
[100885848,"'PTGES3L'",3.98,13.95,11.35,9.76,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0051879///Hsp90 protein binding+++GO:0051087///chaperone binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","prostaglandin E synthase 3 like","[PTG3L_HUMAN|Reviewed]RecName: Full=Putative protein PTGES3L; AltName: Full=Prostaglandin E synthase 3-like;+++[B9A003_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000386902};+++[C9JG77_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000404440}; Flags: Fragment;+++[H7C1Q7_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000467778}; Flags: Fragment;+++[K7N7A2_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000401675}; Flags: Fragment;"]
[100885850,"'PTGES3L-AARSD1'",4.46,6.71,5.13,5.43333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004813///alanine-tRNA ligase activity","GO:0006419///alanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation","PTGES3L-AARSD1 readthrough","[AASD1_HUMAN|Reviewed]RecName: Full=Alanyl-tRNA editing protein Aarsd1; AltName: Full=Alanyl-tRNA synthetase domain-containing protein 1;+++[C9J5N1_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000386254};+++[C9JUA3_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393780}; Flags: Fragment;+++[H7C054_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393019}; Flags: Fragment;+++[L7N2F6_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000407951}; Flags: Fragment;"]
[10089,"'KCNK7'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0022841///potassium ion leak channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity","GO:0006813///potassium ion transport+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport","potassium two pore domain channel subfamily K member 7","[KCNK7_HUMAN|Reviewed]RecName: Full=Potassium channel subfamily K member 7;+++[A0A024R5B0_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_c {ECO:0000313|EMBL:EAW74415.1};+++[A0A024R5F5_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_b {ECO:0000313|EMBL:EAW74414.1};+++[H0YCM4_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000431950}; Flags: Fragment;+++[H0YEB9_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000435449}; Flags: Fragment;+++[Q3MI97_HUMAN|Unreviewed]SubName: Full=KCNK7 protein {ECO:0000313|EMBL:AAI03812.2}; Flags: Fragment;+++[Q3SYI1_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7 {ECO:0000313|EMBL:AAI03811.1};"]
[1009,"'CDH11'",1416,1278,1025,1239.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01513///Retinoblastoma",null,null,"GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0070062///extracellular exosome+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse+++GO:0005737///cytoplasm","GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding","GO:0021957///corticospinal tract morphogenesis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0001503///ossification+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050804///modulation of chemical synaptic transmission+++GO:0001501///skeletal system development","cadherin 11","[CAD11_HUMAN|Reviewed]RecName: Full=Cadherin-11; AltName: Full=OSF-4; AltName: Full=Osteoblast cadherin; Short=OB-cadherin; Flags: Precursor;+++[A0A087X227_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000484650}; Flags: Fragment;+++[H3BP26_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455120}; Flags: Fragment;+++[H3BPQ2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455420}; Flags: Fragment;+++[H3BQB5_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455697}; Flags: Fragment;+++[H3BQH2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455779}; Flags: Fragment;+++[H3BR78_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456110}; Flags: Fragment;+++[H3BSM4_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456772}; Flags: Fragment;+++[H3BUU9_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000457812};+++[Q96CZ9_HUMAN|Unreviewed]SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast) {ECO:0000313|EMBL:AAH13609.1}; SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast), isoform CRA_c {ECO:0000313|EMBL:EAW83002.1};"]
[10090,"'UST'",49,50,71,56.6666666666667,"00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0050770///regulation of axonogenesis+++GO:0006477///protein sulfation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030010///establishment of cell polarity","uronyl 2-sulfotransferase","[UST_HUMAN|Reviewed]RecName: Full=Uronyl 2-sulfotransferase; EC=2.8.2.-;"]
[10092,"'ARPC5'",2467,2103,1982,2184,"05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++04144///Endocytosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0034774///secretory granule lumen+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005885///Arp2/3 protein complex","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0030036///actin cytoskeleton organization+++GO:0030011///maintenance of cell polarity+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0051639///actin filament network formation+++GO:0016477///cell migration+++GO:0061024///membrane organization+++GO:0097581///lamellipodium organization+++GO:0061842///microtubule organizing center localization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0014909///smooth muscle cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0021769///orbitofrontal cortex development","actin related protein 2/3 complex subunit 5","[ARPC5_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5; AltName: Full=Arp2/3 complex 16 kDa subunit; Short=p16-ARC;+++[B1ALC0_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};+++[Q6IPM3_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};"]
[10093,"'ARPC4'",1632.32,1778.47,1540.69,1650.49333333333,"04144///Endocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton","GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0051015///actin filament binding+++GO:0030674///protein binding, bridging+++GO:0003779///actin binding","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0045010///actin nucleation+++GO:0030041///actin filament polymerization+++GO:0048013///ephrin receptor signaling pathway+++GO:0061024///membrane organization+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis","actin related protein 2/3 complex subunit 4","[ARPC4_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4; AltName: Full=Arp2/3 complex 20 kDa subunit; Short=p20-ARC;+++[F8WDD7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000395085};+++[F8WDW3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000414751};+++[R4GN08_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000473435}; Flags: Fragment;"]
[10094,"'ARPC3'",1451,1507,1326,1428,"05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++04144///Endocytosis+++05131///Shigellosis+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0031941///filamentous actin+++GO:0061850///growth cone leading edge+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0031252///cell leading edge+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0070358///actin polymerization-dependent cell motility","actin related protein 2/3 complex subunit 3","[ARPC3_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3; AltName: Full=Arp2/3 complex 21 kDa subunit; Short=p21-ARC;+++[C9JZD1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000413221}; Flags: Fragment;+++[F8VR50_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000446598}; Flags: Fragment;+++[Q2LE71_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000256|PIRNR:PIRNR016315}; AltName: Full=Arp2/3 complex 21 kDa subunit {ECO:0000256|PIRNR:PIRNR016315};"]
[10095,"'ARPC1B'",1535,1701,1456,1564,"05131///Shigellosis+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0036284///tubulobulbar complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0032355///response to estradiol+++GO:0043627///response to estrogen+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization","actin related protein 2/3 complex subunit 1B","[ARC1B_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1B; AltName: Full=Arp2/3 complex 41 kDa subunit; AltName: Full=p41-ARC;+++[A4D275_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};+++[C9J4Z7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000410238}; Flags: Fragment;+++[C9J6C8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398110}; Flags: Fragment;+++[C9JBJ7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398620}; Flags: Fragment;+++[C9JEY1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403324}; Flags: Fragment;+++[C9JFG9_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403211}; Flags: Fragment;+++[C9JM51_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408758}; Flags: Fragment;+++[C9JQM8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000388802}; Flags: Fragment;+++[C9JTT6_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413067}; Flags: Fragment;+++[C9K057_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413173};+++[F8VXW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000399955};+++[F8WEB3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408508};+++[L8EAG6_HUMAN|Unreviewed]SubName: Full=Alternative protein ARPC1B {ECO:0000313|EMBL:CCQ43333.1};"]
[10096,"'ACTR3'",2823,2622,2481,2642,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0035861///site of double-strand break+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0030027///lamellipodium+++GO:0005911///cell-cell junction","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005524///ATP binding+++GO:0003779///actin binding","GO:0007163///establishment or maintenance of cell polarity+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0071346///cellular response to interferon-gamma+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070358///actin polymerization-dependent cell motility+++GO:0008356///asymmetric cell division+++GO:0060271///cilium assembly+++GO:0033206///meiotic cytokinesis+++GO:0007015///actin filament organization+++GO:0061024///membrane organization+++GO:0051321///meiotic cell cycle+++GO:0051653///spindle localization+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0048013///ephrin receptor signaling pathway+++GO:0030030///cell projection organization","ARP3 actin related protein 3 homolog","[ARP3_HUMAN|Reviewed]RecName: Full=Actin-related protein 3; AltName: Full=Actin-like protein 3;+++[A0A024RAI1_HUMAN|Unreviewed]SubName: Full=ARP3 actin-related protein 3 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW95180.1};+++[B4DXW1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000444987}; SubName: Full=cDNA FLJ51148, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63684.1}; SubName: Full=cDNA FLJ52434, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63523.1}; SubName: Full=cDNA, FLJ79112, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14584.1}; SubName: Full=cDNA, FLJ79295, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14767.1};+++[F8WDR7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000403125}; Flags: Fragment;+++[F8WE84_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000394213};+++[F8WEW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000407912};"]
[10097,"'ACTR2'",2704,2027,2056,2262.33333333333,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0014069///postsynaptic density+++GO:0035861///site of double-strand break+++GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071437///invadopodium+++GO:0030027///lamellipodium+++GO:0005856///cytoskeleton+++GO:0035578///azurophil granule lumen+++GO:0098794///postsynapse+++GO:0061825///podosome core+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0042995///cell projection+++GO:0030478///actin cap","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0051015///actin filament binding+++GO:0008092///cytoskeletal protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0061024///membrane organization+++GO:0033206///meiotic cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:0007015///actin filament organization+++GO:0043312///neutrophil degranulation+++GO:0008306///associative learning+++GO:0035902///response to immobilization stress+++GO:0045471///response to ethanol+++GO:0016482///cytosolic transport+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0008356///asymmetric cell division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining+++GO:0007163///establishment or maintenance of cell polarity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0060271///cilium assembly+++GO:0051321///meiotic cell cycle+++GO:0035984///cellular response to trichostatin A+++GO:0071346///cellular response to interferon-gamma+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0051653///spindle localization","ARP2 actin related protein 2 homolog","[ARP2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2; AltName: Full=Actin-like protein 2;+++[A0A1B0GWD0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490877};+++[A0A1B0GWH0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490923};+++[F5H6T1_HUMAN|Unreviewed]SubName: Full=ARP2 actin-related protein 2 homolog (Yeast), isoform CRA_d {ECO:0000313|EMBL:EAW99914.1}; SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000437383};+++[Q8IY98_HUMAN|Unreviewed]SubName: Full=ACTR2 protein {ECO:0000313|EMBL:AAH36253.1};"]
[10098,"'TSPAN5'",728,706,804,746,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0019899///enzyme binding","GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane+++GO:0007166///cell surface receptor signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0045747///positive regulation of Notch signaling pathway","tetraspanin 5","[TSN5_HUMAN|Reviewed]RecName: Full=Tetraspanin-5; Short=Tspan-5; AltName: Full=Tetraspan NET-4; AltName: Full=Transmembrane 4 superfamily member 9;+++[B7Z317_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[D6R9N6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000423504}; Flags: Fragment;+++[D6RAR1_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000421808};+++[D6RBT5_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422548};+++[D6RGZ7_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000426248}; Flags: Fragment;+++[H0Y8W4_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422351}; Flags: Fragment;+++[Q6FHC5_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[10099,"'TSPAN3'",6192,5860,6276,6109.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway","H00287///Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0007166///cell surface receptor signaling pathway+++GO:0008150///biological_process","tetraspanin 3","[TSN3_HUMAN|Reviewed]RecName: Full=Tetraspanin-3; Short=Tspan-3; AltName: Full=Tetraspanin TM4-A; AltName: Full=Transmembrane 4 superfamily member 8;+++[H0YKJ9_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000452835};+++[H0YMH8_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000453613};+++[L8E893_HUMAN|Unreviewed]SubName: Full=Alternative protein TSPAN3 {ECO:0000313|EMBL:CCQ43334.1};"]
[100996259,"'FAM106B'",1.31,5.32,5.08,3.90333333333333,{"$nulls":7},"family with sequence similarity 106 member B","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[F106A_HUMAN|diamond]RecName: Full=Protein FAM106A;+++[F106C_HUMAN|diamond]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[100996318,"'LOC100996318'",3.01,0,1,1.33666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006334///nucleosome assembly","uncharacterized LOC100996318","[H2B1_BOVIN|diamond]RecName: Full=Histone H2B type 1;+++[H2B1H_HUMAN|diamond]RecName: Full=Histone H2B type 1-H; AltName: Full=Histone H2B.j; Short=H2B/j;+++[H2B1O_HUMAN|diamond]RecName: Full=Histone H2B type 1-O; AltName: Full=Histone H2B.2; AltName: Full=Histone H2B.n; Short=H2B/n;+++[H2B2B_MOUSE|diamond]RecName: Full=Histone H2B type 2-B; AltName: Full=H2b 616;+++[H2B2F_HUMAN|diamond]RecName: Full=Histone H2B type 2-F;"]
[100996379,"'LOC100996379'",2,2,1,1.66666666666667,"04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal+++04137///Mitophagy - animal","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0032183///SUMO binding+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0007283///spermatogenesis+++GO:0006886///intracellular protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0016567///protein ubiquitination+++GO:0006974///cellular response to DNA damage stimulus","E3 ubiquitin-protein ligase HERC2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996414,"'100996414'",26.18,35.27,54.51,38.6533333333333,{"$nulls":8},"[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[100996485,"'C5orf66'",0,1,0,0.333333333333333,"05034///Alcoholism+++04140///Autophagy - animal+++04217///Necroptosis+++04137///Mitophagy - animal+++05322///Systemic lupus erythematosus","H00903///Congenital clubfoot",null,null,"GO:0070062///extracellular exosome+++GO:0000793///condensed chromosome+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0001739///sex chromatin+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005721///pericentric heterochromatin+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0000786///nucleosome+++GO:0000790///nuclear chromatin+++GO:0000228///nuclear chromosome","GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0031490///chromatin DNA binding+++GO:0019901///protein kinase binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0019899///enzyme binding+++GO:1990841///promoter-specific chromatin binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0000182///rDNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0035116///embryonic hindlimb morphogenesis+++GO:1902883///negative regulation of response to oxidative stress+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007549///dosage compensation+++GO:1902884///positive regulation of response to oxidative stress+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0006342///chromatin silencing+++GO:0001501///skeletal system development+++GO:0051216///cartilage development+++GO:1904815///negative regulation of protein localization to chromosome, telomeric region+++GO:0006355///regulation of transcription, DNA-templated+++GO:1902750///negative regulation of cell cycle G2/M phase transition+++GO:0071169///establishment of protein localization to chromatin+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0006351///transcription, DNA-templated+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:0019216///regulation of lipid metabolic process+++GO:0014707///branchiomeric skeletal muscle development+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0040029///regulation of gene expression, epigenetic+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0033128///negative regulation of histone phosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0006334///nucleosome assembly+++GO:0048625///myoblast fate commitment+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902882///regulation of response to oxidative stress+++GO:0021983///pituitary gland development+++GO:0045618///positive regulation of keratinocyte differentiation","chromosome 5 open reading frame 66","[CE066_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C5orf66;"]
[100996492,"'CTXND1'",4,5,7,5.33333333333333,null,"H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane+++GO:0016020///membrane",null,null,"cortexin domain containing 1","[CTXD1_HUMAN|Reviewed]RecName: Full=Cortexin domain-containing 1 {ECO:0000305};"]
[100996517,"'SEC22B3'",258.83,167.77,146.99,191.196666666667,"04145///Phagosome+++04130///SNARE interactions in vesicular transport+++05134///Legionellosis",{"$nulls":3},"GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000139///Golgi membrane+++GO:0042470///melanosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0008021///synaptic vesicle+++GO:0030133///transport vesicle","GO:0000149///SNARE binding+++GO:0019905///syntaxin binding+++GO:0005484///SNAP receptor activity","GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:1902902///negative regulation of autophagosome assembly+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0045732///positive regulation of protein catabolic process+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent","SEC22 homolog B3","[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996643,"'LOC100996643'",5,1,0,2,"00670///One carbon pool by folate+++04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005739///mitochondrion","GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0005524///ATP binding+++GO:0015267///channel activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008236///serine-type peptidase activity+++GO:0042803///protein homodimerization activity+++GO:0004180///carboxypeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity+++GO:0004329///formate-tetrahydrofolate ligase activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity","GO:0042135///neurotransmitter catabolic process+++GO:0006508///proteolysis+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0001843///neural tube closure+++GO:0006760///folic acid-containing compound metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0009113///purine nucleobase biosynthetic process+++GO:0046655///folic acid metabolic process+++GO:0015942///formate metabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0009257///10-formyltetrahydrofolate biosynthetic process","monofunctional C1-tetrahydrofolate synthase, mitochondrial-like","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[TR43B_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43B;+++[TRI43_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996693,"'LOC100996693'",10,7,1,6,{"$nulls":7},"CAVP-target protein-like","[A0A087WV53_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000479190};"]
[100996709,"'LOC100996709'",127.54,160.67,125.59,137.933333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore","GO:0005525///GTP binding+++GO:0008270///zinc ion binding+++GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0004181///metallocarboxypeptidase activity+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)","GO:0043984///histone H4-K16 acetylation+++GO:0015031///protein transport+++GO:0035610///protein side chain deglutamylation+++GO:0043981///histone H4-K5 acetylation+++GO:0016192///vesicle-mediated transport+++GO:0043982///histone H4-K8 acetylation","ADP-ribosylation factor-like protein 17","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};"]
[100996716,"'SEC22B2'",107.8,152.95,172.63,144.46,"04145///Phagosome+++05134///Legionellosis+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030133///transport vesicle+++GO:0042470///melanosome+++GO:0030670///phagocytic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0031201///SNARE complex+++GO:0000139///Golgi membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005789///endoplasmic reticulum membrane+++GO:0005622///intracellular+++GO:0016021///integral component of membrane","GO:0005484///SNAP receptor activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0045732///positive regulation of protein catabolic process+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0015031///protein transport+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane","SEC22 homolog B2","[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996717,"'NOTCH2NLC'",230.17,169.26,170.25,189.893333333333,"01522///Endocrine resistance+++05224///Breast cancer+++04320///Dorso-ventral axis formation+++05200///Pathways in cancer+++04919///Thyroid hormone signaling pathway+++04658///Th1 and Th2 cell differentiation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection","H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development+++GO:0045747///positive regulation of Notch signaling pathway","notch 2 N-terminal like C","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NC_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[100996720,"'LOC100996720'",150,162,151,154.333333333333,{"$nulls":4},"GO:0005622///intracellular","GO:0003950///NAD+ ADP-ribosyltransferase activity",null,"uncharacterized LOC100996720","[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;"]
[100996741,"'100996741'",1.74,16,9,8.91333333333333,{"$nulls":8},"[F231A_HUMAN|diamond]RecName: Full=Putative protein FAM231AP {ECO:0000305};+++[F231B_HUMAN|diamond]RecName: Full=Putative protein FAM231BP;+++[F231C_HUMAN|diamond]RecName: Full=Protein FAM231C;+++[F231D_HUMAN|diamond]RecName: Full=Protein FAM231D;+++[F231L_HUMAN|diamond]RecName: Full=FAM231A/C-like protein LOC102723383;"]
[100996747,"'LOC100996747'",84.16,61.97,101.59,82.5733333333333,{"$nulls":4},"GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane+++GO:0022627///cytosolic small ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0003729///mRNA binding","GO:0002181///cytoplasmic translation+++GO:0033119///negative regulation of RNA splicing","40S ribosomal protein S26","[RS26_BOVIN|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_HUMAN|diamond]RecName: Full=40S ribosomal protein S26; AltName: Full=Small ribosomal subunit protein eS26 {ECO:0000303|PubMed:24524803};+++[RS26_MACFA|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_MOUSE|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_PIG|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_RAT|diamond]RecName: Full=40S ribosomal protein S26;"]
[100996758,"'NPY4R2'",3.85,3,0,2.28333333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0001602///pancreatic polypeptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017046///peptide hormone binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007218///neuropeptide signaling pathway","neuropeptide Y receptor Y4-2","[NPY4R_HUMAN|Reviewed]RecName: Full=Neuropeptide Y receptor type 4; Short=NPY4-R; AltName: Full=Pancreatic polypeptide receptor 1; Short=PP1;"]
[100996763,"'NOTCH2NLB'",239.96,182.3,254.74,225.666666666667,"05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005112///Notch binding+++GO:0005515///protein binding","GO:0045747///positive regulation of Notch signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development","notch 2 N-terminal like B","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[A0A0B4J2B3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 14 {ECO:0000313|Ensembl:ENSP00000472124};"]
[100996792,"'LOC100996792'",1,1,1.01,1.00333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0004708///MAP kinase kinase activity+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity","GO:0031098///stress-activated protein kinase signaling cascade+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006954///inflammatory response+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0000187///activation of MAPK activity+++GO:0042981///regulation of apoptotic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060048///cardiac muscle contraction+++GO:0023014///signal transduction by protein phosphorylation+++GO:0007165///signal transduction+++GO:0038066///p38MAPK cascade+++GO:0032147///activation of protein kinase activity+++GO:0007346///regulation of mitotic cell cycle+++GO:0043536///positive regulation of blood vessel endothelial cell migration","dual specificity mitogen-activated protein kinase kinase 3 pseudogene","[MP2K3_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000269|PubMed:8622669}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3; AltName: Full=Stress-activated protein kinase kinase 2; Short=SAPK kinase 2; Short=SAPKK-2; Short=SAPKK2;+++[MP2K3_MOUSE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000250|UniProtKB:P46734}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3;+++[MP2K6_BOVIN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6;+++[MP2K6_DANRE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAP kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAPKK 6 {ECO:0000250|UniProtKB:P52564}; EC=2.7.12.2; AltName: Full=Mitogen-activated protein kinase kinase 3 {ECO:0000303|PubMed:10995439}; Short=zMKK3 {ECO:0000312|EMBL:BAB11809.1};+++[MP2K6_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6; AltName: Full=Stress-activated protein kinase kinase 3; Short=SAPK kinase 3; Short=SAPKK-3; Short=SAPKK3;"]
[100996842,"'LOC100996842'",20,15,12,15.6666666666667,"04142///Lysosome",{"$nulls":3},"GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane",null,"GO:0043312///neutrophil degranulation+++GO:0071310///cellular response to organic substance","uncharacterized LOC100996842","[CD68_HUMAN|diamond]RecName: Full=Macrosialin; AltName: Full=Gp110; AltName: CD_antigen=CD68; Flags: Precursor;+++[CD68_MOUSE|diamond]RecName: Full=Macrosialin; AltName: CD_antigen=CD68; Flags: Precursor;+++[MPU1_CRIGR|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation; Short=SL15;+++[MPU1_HUMAN|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;+++[MPU1_MOUSE|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;"]
[100996911,"'LOC100996911'",7,0,0.5,2.5,{"$nulls":4},"GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0031258///lamellipodium membrane+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0043202///lysosomal lumen+++GO:0005576///extracellular region+++GO:0016324///apical plasma membrane+++GO:0005796///Golgi lumen+++GO:0062023///collagen-containing extracellular matrix","GO:0019901///protein kinase binding","GO:0035556///intracellular signal transduction+++GO:0000187///activation of MAPK activity+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0008283///cell proliferation+++GO:0048771///tissue remodeling+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030207///chondroitin sulfate catabolic process+++GO:0008347///glial cell migration+++GO:0001525///angiogenesis+++GO:0030208///dermatan sulfate biosynthetic process","putative ubiquitin-conjugating enzyme E2Q2-like protein","[A0A024R018_HUMAN|Unreviewed]SubName: Full=HCG1818167, isoform CRA_a {ECO:0000313|EMBL:EAW55850.1};"]
[100996928,"'C7orf55-LUC7L2'",32.07,30.36,0,20.81,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0071004///U2-type prespliceosome+++GO:0005685///U1 snRNP+++GO:0016607///nuclear speck+++GO:0005739///mitochondrion","GO:0003729///mRNA binding+++GO:0019899///enzyme binding+++GO:0003723///RNA binding","GO:0050995///negative regulation of lipid catabolic process+++GO:0006376///mRNA splice site selection+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly","C7orf55-LUC7L2 readthrough","[FMC1_HUMAN|Reviewed]RecName: Full=Protein FMC1 homolog; AltName: Full=ATP synthase assembly factor FMC1, mitochondrial {ECO:0000312|HGNC:HGNC:26946}; AltName: Full=Formation of mitochondrial complex V assembly factor 1 homolog {ECO:0000312|HGNC:HGNC:26946};+++[A0A0A6YYJ8_HUMAN|Unreviewed]SubName: Full=Putative RNA-binding protein Luc7-like 2 {ECO:0000313|Ensembl:ENSP00000440222};"]
[100996939,"'PYURF'",404.5,373,358,378.5,"00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis+++01100///Metabolic pathways","H01488///Hyperphosphatasia with mental retardation syndrome (HPMPS)+++H01489///Inherited glycosylphosphatidylinositol (GPI) deficiencies",null,"R05916///UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143","GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0009893///positive regulation of metabolic process+++GO:0006506///GPI anchor biosynthetic process","PIGY upstream reading frame","[PREY_HUMAN|Reviewed]RecName: Full=Protein preY, mitochondrial; AltName: Full=PIGY upstream reading frame protein; Flags: Precursor;"]
[101,"'ADAM8'",87,64,113,88,{"$nulls":4},"GO:0070821///tertiary granule membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0042581///specific granule+++GO:0032127///dense core granule membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0032010///phagolysosome+++GO:0016020///membrane+++GO:0070820///tertiary granule+++GO:0071065///alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex+++GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0002102///podosome+++GO:0035579///specific granule membrane+++GO:0071133///alpha9-beta1 integrin-ADAM8 complex","GO:0008237///metallopeptidase activity+++GO:0050839///cell adhesion molecule binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0043621///protein self-association","GO:0071456///cellular response to hypoxia+++GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:2000418///positive regulation of eosinophil migration+++GO:0043406///positive regulation of MAP kinase activity+++GO:0050714///positive regulation of protein secretion+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0045780///positive regulation of bone resorption+++GO:2000415///positive regulation of fibronectin-dependent thymocyte migration+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0001525///angiogenesis+++GO:0045089///positive regulation of innate immune response+++GO:0022617///extracellular matrix disassembly+++GO:0002693///positive regulation of cellular extravasation+++GO:2000406///positive regulation of T cell migration+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:2000309///positive regulation of tumor necrosis factor (ligand) superfamily member 11 production+++GO:0010954///positive regulation of protein processing+++GO:0043312///neutrophil degranulation+++GO:0050729///positive regulation of inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0098609///cell-cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0048247///lymphocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0022407///regulation of cell-cell adhesion","ADAM metallopeptidase domain 8","[ADAM8_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 8; Short=ADAM 8; EC=3.4.24.-; AltName: Full=Cell surface antigen MS2; AltName: CD_antigen=CD156a; Flags: Precursor;+++[H0YKZ1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000452994};+++[H0YMT6_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000453735}; Flags: Fragment;+++[Q14C66_HUMAN|Unreviewed]SubName: Full=ADAM8 protein {ECO:0000313|EMBL:AAI15405.1}; SubName: Full=cDNA, FLJ93272, highly similar to Homo sapiens a disintegrin and metalloproteinase domain 8 (ADAM8),mRNA {ECO:0000313|EMBL:BAG35688.1};"]
[1010,"'CDH12'",4,3,7,4.66666666666667,{"$nulls":4},"GO:0016342///catenin complex+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding","GO:0034332///adherens junction organization+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","cadherin 12","[CAD12_HUMAN|Reviewed]RecName: Full=Cadherin-12; AltName: Full=Brain cadherin; Short=BR-cadherin; AltName: Full=Neural type cadherin 2; Short=N-cadherin 2; Flags: Precursor;"]
[10100,"'TSPAN2'",191,166,148,168.333333333333,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0007166///cell surface receptor signaling pathway+++GO:0048709///oligodendrocyte differentiation+++GO:0014005///microglia development+++GO:0014002///astrocyte development+++GO:0006954///inflammatory response+++GO:0042552///myelination+++GO:0061564///axon development+++GO:0007420///brain development","tetraspanin 2","[TSN2_HUMAN|Reviewed]RecName: Full=Tetraspanin-2; Short=Tspan-2; AltName: Full=Tetraspan NET-3;+++[B1AKP1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[B1AKP2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[B2RD31_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};"]
[10101,"'NUBP2'",778,844,836.31,819.436666666667,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0005929///cilium+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0000166///nucleotide binding+++GO:0051536///iron-sulfur cluster binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0051642///centrosome localization+++GO:0001558///regulation of cell growth+++GO:0030030///cell projection organization+++GO:0006879///cellular iron ion homeostasis+++GO:0010826///negative regulation of centrosome duplication+++GO:0016226///iron-sulfur cluster assembly+++GO:0072697///protein localization to cell cortex","nucleotide binding protein 2","[NUBP2_HUMAN|Reviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000255|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000255|HAMAP-Rule:MF_03039};+++[B2RDN3_HUMAN|Unreviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000256|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000256|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000256|HAMAP-Rule:MF_03039};+++[B7Z6P0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000460079}; SubName: Full=Nucleotide binding protein 2 (MinD homolog, E. coli), isoform CRA_d {ECO:0000313|EMBL:EAW85616.1}; SubName: Full=cDNA FLJ57200, highly similar to Nucleotide-binding protein 2 {ECO:0000313|EMBL:BAH13326.1};+++[H3BMW1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454576}; Flags: Fragment;+++[H3BNF0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454815};+++[H3BNS4_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454982}; Flags: Fragment;+++[H3BQE5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455739}; Flags: Fragment;+++[H3BQR2_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455896};+++[H3BRE1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456199}; Flags: Fragment;+++[H3BRK5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456284};+++[I3L3A0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000460288}; Flags: Fragment;+++[I3L518_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461723}; Flags: Fragment;+++[I3L531_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461746}; Flags: Fragment;+++[Q2YS46_HUMAN|Unreviewed]SubName: Full=C447E6.1 (Nucleotide binding protein 1 (E.coli MinD like) ) {ECO:0000313|EMBL:CAC36077.1}; Flags: Fragment;"]
[10102,"'TSFM'",195,186,191,190.666666666667,null,"H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0003746///translation elongation factor activity+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0006414///translational elongation+++GO:0070129///regulation of mitochondrial translation+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","Ts translation elongation factor, mitochondrial","[EFTS_HUMAN|Reviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135}; Flags: Precursor;+++[B4DHY8_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[C9JG32_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000390679}; Flags: Fragment;+++[C9JT21_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000389162}; Flags: Fragment;+++[E5KS95_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VPA7_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VS27_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8WCK2_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000406339};"]
[10103,"'TSPAN1'",42,27,26,31.6666666666667,"04213///Longevity regulating pathway - multiple species+++04071///Sphingolipid signaling pathway+++04218///Cellular senescence+++05166///HTLV-I infection+++04360///Axon guidance+++05161///Hepatitis B+++05212///Pancreatic cancer+++05164///Influenza A+++04666///Fc gamma R-mediated phagocytosis+++05162///Measles+++01521///EGFR tyrosine kinase inhibitor resistance+++04211///Longevity regulating pathway+++05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++04931///Insulin resistance+++05225///Hepatocellular carcinoma+++05146///Amoebiasis+++05165///Human papillomavirus infection+++04910///Insulin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04150///mTOR signaling pathway+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++05226///Gastric cancer+++05221///Acute myeloid leukemia+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++04722///Neurotrophin signaling pathway+++05210///Colorectal cancer+++04750///Inflammatory mediator regulation of TRP channels+++04072///Phospholipase D signaling pathway+++04917///Prolactin signaling pathway+++05213///Endometrial cancer+++05220///Chronic myeloid leukemia+++04152///AMPK signaling pathway+++04926///Relaxin signaling pathway+++05223///Non-small cell lung cancer+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04210///Apoptosis+++04630///Jak-STAT signaling pathway+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++05163///Human cytomegalovirus infection+++04810///Regulation of actin cytoskeleton+++04380///Osteoclast differentiation+++04012///ErbB signaling pathway+++04611///Platelet activation+++01524///Platinum drug resistance+++05160///Hepatitis C+++04014///Ras signaling pathway+++04625///C-type lectin receptor signaling pathway+++05215///Prostate cancer+++05222///Small cell lung cancer+++04070///Phosphatidylinositol signaling system+++05224///Breast cancer+++04510///Focal adhesion+++05231///Choline metabolism in cancer+++05203///Viral carcinogenesis+++04140///Autophagy - animal+++05230///Central carbon metabolism in cancer+++04930///Type II diabetes mellitus+++01522///Endocrine resistance+++04670///Leukocyte transendothelial migration+++04919///Thyroid hormone signaling pathway+++05218///Melanoma+++05142///Chagas disease (American trypanosomiasis)+++05214///Glioma+++04550///Signaling pathways regulating pluripotency of stem cells+++04370///VEGF signaling pathway+++04973///Carbohydrate digestion and absorption+++04062///Chemokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04650///Natural killer cell mediated cytotoxicity+++04620///Toll-like receptor signaling pathway+++04068///FoxO signaling pathway+++04915///Estrogen signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04024///cAMP signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++05169///Epstein-Barr virus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04725///Cholinergic synapse+++04960///Aldosterone-regulated sodium reabsorption","H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01370///SHORT syndrome","M00676///PI3K-Akt signaling","R03362///ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate+++R04545///ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate+++R05795///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate","GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane+++GO:0031982///vesicle+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0045807///positive regulation of endocytosis+++GO:0007166///cell surface receptor signaling pathway+++GO:0050821///protein stabilization+++GO:0008283///cell proliferation+++GO:0016477///cell migration","tetraspanin 1","[TSN1_HUMAN|Reviewed]RecName: Full=Tetraspanin-1; Short=Tspan-1; AltName: Full=Tetraspan NET-1; AltName: Full=Tetraspanin TM4-C;"]
[10105,"'PPIF'",382,413,581,458.666666666667,"04020///Calcium signaling pathway+++05016///Huntington's disease+++05145///Toxoplasmosis+++05012///Parkinson's disease+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005753///mitochondrial proton-transporting ATP synthase complex","GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0042277///peptide binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding","GO:0012501///programmed cell death+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0010939///regulation of necrotic cell death+++GO:0002931///response to ischemia+++GO:0043066///negative regulation of apoptotic process+++GO:0010849///regulation of proton-transporting ATPase activity, rotational mechanism+++GO:0006457///protein folding+++GO:0008637///apoptotic mitochondrial changes+++GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0032780///negative regulation of ATPase activity+++GO:2000276///negative regulation of oxidative phosphorylation uncoupler activity+++GO:0071243///cellular response to arsenic-containing substance+++GO:0006979///response to oxidative stress+++GO:1902686///mitochondrial outer membrane permeabilization involved in programmed cell death+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0071277///cellular response to calcium ion+++GO:0070301///cellular response to hydrogen peroxide+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0070266///necroptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria","peptidylprolyl isomerase F","[PPIF_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase F, mitochondrial; Short=PPIase F; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Cyclophilin D; Short=CyP-D; Short=CypD; AltName: Full=Cyclophilin F; AltName: Full=Mitochondrial cyclophilin; Short=CyP-M; AltName: Full=Rotamase F; Flags: Precursor;+++[A0A024QZS4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[H0Y548_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[R4GN99_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[101059906,"'LOC101059906'",15,8,9,10.6666666666667,"01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,null,"R07376///L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0098978///glutamatergic synapse+++GO:0000139///Golgi membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol","GO:0019003///GDP binding+++GO:0016740///transferase activity+++GO:0003924///GTPase activity+++GO:0003882///CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0005525///GTP binding+++GO:0008022///protein C-terminus binding","GO:0071480///cellular response to gamma radiation+++GO:0090303///positive regulation of wound healing+++GO:0048013///ephrin receptor signaling pathway+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007265///Ras protein signal transduction+++GO:0051291///protein heterooligomerization+++GO:0034260///negative regulation of GTPase activity+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0042088///T-helper 1 type immune response+++GO:0043406///positive regulation of MAP kinase activity+++GO:0006897///endocytosis+++GO:0043547///positive regulation of GTPase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0010629///negative regulation of gene expression+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:2000630///positive regulation of miRNA metabolic process+++GO:0046330///positive regulation of JNK cascade+++GO:0008283///cell proliferation+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0006935///chemotaxis+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1900029///positive regulation of ruffle assembly+++GO:0007165///signal transduction+++GO:0000165///MAPK cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0090398///cellular senescence+++GO:0035900///response to isolation stress+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0010863///positive regulation of phospholipase C activity+++GO:0050852///T cell receptor signaling pathway+++GO:0042832///defense response to protozoan+++GO:0045740///positive regulation of DNA replication+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0007050///cell cycle arrest+++GO:0001934///positive regulation of protein phosphorylation+++GO:0043524///negative regulation of neuron apoptotic process","collagen alpha-2(IV) chain-like","[CO3A1_CHICK|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor; Fragments;+++[CO3A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(IV) chain; Contains: RecName: Full=Arresten; Flags: Precursor;+++[CO7A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(VII) chain; AltName: Full=Long-chain collagen; Short=LC collagen; Flags: Precursor;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[LRC56_HUMAN|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_MOUSE|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_RAT|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[PTSS2_CHICK|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_CRIGR|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_HUMAN|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_MOUSE|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_RAT|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[RASH_CHICK|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_HUMAN|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Ha-Ras; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_MOUSE|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_RAT|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASK_KRYMA|diamond]RecName: Full=GTPase KRas; AltName: Full=Ki-Ras; Short=K-ras; Flags: Precursor;+++[RASK_MONDO|diamond]RecName: Full=GTPase KRas; AltName: Full=K-Ras 2; AltName: Full=Ki-Ras; AltName: Full=c-K-ras; AltName: Full=c-Ki-ras; Contains: RecName: Full=GTPase KRas, N-terminally processed; Flags: Precursor;+++[RINI_HUMAN|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Placental ribonuclease inhibitor; Short=Placental RNase inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1; Short=RAI;+++[RINI_PANTR|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_PIG|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_RAT|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[101059918,"'GOLGA8R'",26.73,11.82,18.46,19.0033333333333,"04530///Tight junction",{"$nulls":3},"GO:0005794///Golgi apparatus",null,null,"golgin A8 family member R","[GOG8R_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 8R;"]
[101059938,"'NPIPA7'",796.7,995.15,894.11,895.32,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"nuclear pore complex interacting protein family member A7","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0Y2X3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A7 {ECO:0000313|Ensembl:ENSP00000343256}; Flags: Fragment;"]
[101059949,"'LOC101059949'",3.25,1.51,1.47,2.07666666666667,{"$nulls":7},"putative ankyrin repeat domain-containing protein 20A12 pseudogene","[A2012_HUMAN|diamond]RecName: Full=Putative ankyrin repeat domain-containing protein 20A12 pseudogene {ECO:0000305};+++[AN18A_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18A;+++[AN18B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18B;+++[ANR26_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000305};+++[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;"]
[101059953,"'NPIPA8'",154.37,212.13,252.16,206.22,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"nuclear pore complex interacting protein family member A8","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0YFN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A8 {ECO:0000313|Ensembl:ENSP00000439498}; Flags: Fragment;"]
[10106,"'CTDSP2'",1123,1074,1340,1179,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0016791///phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0016311///dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle","CTD small phosphatase 2","[CTDS2_HUMAN|Reviewed]RecName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; EC=3.1.3.16; AltName: Full=Nuclear LIM interactor-interacting factor 2; Short=NLI-interacting factor 2; AltName: Full=Protein OS-4; AltName: Full=Small C-terminal domain phosphatase 2; AltName: Full=Small CTD phosphatase 2; Short=SCP2;+++[A0A024RB65_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_b {ECO:0000313|EMBL:EAW97086.1};+++[A0A024RBA6_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_c {ECO:0000313|EMBL:EAW97089.1};+++[F8VYL0_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448951};+++[F8W184_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000446705};+++[F8W1I1_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000447046};+++[H0YI12_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448299}; Flags: Fragment;+++[H0YI29_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448386}; Flags: Fragment;"]
[101060017,"'LOC101060017'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0032587///ruffle membrane+++GO:0005829///cytosol","GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0004672///protein kinase activity+++GO:0071889///14-3-3 protein binding+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0000165///MAPK cascade+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0043405///regulation of MAP kinase activity","translation initiation factor IF-2-like","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[KSR2_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 2; Short=hKSR2; EC=2.7.11.1;+++[KSR2_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 2; EC=2.7.11.1;"]
[101060022,"'LOC101060022'",312.66,371.2,392.67,358.843333333333,{"$nulls":7},"nascent polypeptide-associated complex subunit alpha, muscle-specific form-like","[PRR36_HUMAN|diamond]RecName: Full=Proline-rich protein 36 {ECO:0000312|HGNC:HGNC:26172};+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[101060024,"'LOC101060024'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane",null,null,"short transmembrane mitochondrial protein 1-like","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[STMP1_HUMAN|diamond]RecName: Full=Short transmembrane mitochondrial protein 1 {ECO:0000303|PubMed:23073385};+++[STMP1_MOUSE|diamond]RecName: Full=Short transmembrane mitochondrial protein 1 {ECO:0000250|UniProtKB:E0CX11};"]
[101060179,"'LOC101060179'",52,53,49,51.3333333333333,{"$nulls":7},"uncharacterized LOC101060179","[A0A2J8LHJ5_PANTR|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNI46744.1}; Flags: Fragment;+++[A0A2J8WFF8_PONAB|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNJ68516.1}; Flags: Fragment;+++[A0A2R8MD89_CALJA|diamond]SubName: Full=PR/SET domain 11 {ECO:0000313|Ensembl:ENSCJAP00000057788};+++[H3BSZ2_HUMAN|diamond]SubName: Full=PR domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000456942}; Flags: Fragment;+++[Q8N1K6_HUMAN|diamond]SubName: Full=cDNA FLJ40559 fis, clone THYMU2002910 {ECO:0000313|EMBL:BAC05192.1};"]
[101060200,"'ZNF891'",9,2,6,5.66666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 891","[ZN891_HUMAN|Reviewed]RecName: Full=Zinc finger protein 891;"]
[101060226,"'NBPF19'",797.77,606.29,870.38,758.146666666667,"05224///Breast cancer+++01522///Endocrine resistance+++04137///Mitophagy - animal+++04330///Notch signaling pathway+++05200///Pathways in cancer+++04140///Autophagy - animal+++04320///Dorso-ventral axis formation+++04658///Th1 and Th2 cell differentiation+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection+++04919///Thyroid hormone signaling pathway","H00551///Alagille syndrome+++H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","NBPF member 19","[NBPFJ_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};+++[A0A075B6G5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000358229};+++[A0A087X230_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484655};+++[A0A087X288_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484787};"]
[101060254,"'LOC101060254'",65,43.61,53,53.87,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0030016///myofibril","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization+++GO:1903358///regulation of Golgi organization+++GO:0034622///cellular protein-containing complex assembly","myomegalin-like","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_MOUSE|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[CK5P2_RAT|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFK_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 20;+++[NBPFP_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 26;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101060321,"'TBC1D3G'",42.92,15.96,64.65,41.1766666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","TBC1 domain family member 3G","[TBC3C_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3C;+++[TBC3G_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3G;"]
[101060341,"'LOC101060341'",309.33,314.27,355.01,326.203333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC101060341","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101060351,"'TBC1D3K'",19.1,6.01,19.38,14.83,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","TBC1 domain family member 3K","[TBC3K_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3K {ECO:0000312|HGNC:HGNC:51245};+++[A0A0G2JPY0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3K {ECO:0000313|Ensembl:ENSP00000484542};"]
[101060376,"'TBC1D3L'",376.53,494.56,439.08,436.723333333333,{"$nulls":4},"GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0005622///intracellular","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0031338///regulation of vesicle fusion+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3L","[TBC3L_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3L {ECO:0000312|HGNC:HGNC:51246};+++[A0A0G2JP35_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3L {ECO:0000313|Ensembl:ENSP00000482811};+++[B3KTC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38066 fis, clone CTONG2015330, highly similar to TBC1 domain family member 3 {ECO:0000313|EMBL:BAG53037.1};"]
[101060389,"'TBC1D3D'",56.94,31.85,61.84,50.21,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:1902017///regulation of cilium assembly+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3D","[TBC3D_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3D {ECO:0000312|HGNC:HGNC:28944};"]
[101060684,"'NBPF26'",382.63,331.19,387.69,367.17,"04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++04140///Autophagy - animal+++05200///Pathways in cancer+++04137///Mitophagy - animal+++05165///Human papillomavirus infection+++04320///Dorso-ventral axis formation+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++01522///Endocrine resistance+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","NBPF member 26","[NBPFP_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 26;+++[A0A075B7F9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000476257};+++[A0A087WTG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000477847};+++[A0A087WU30_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000478334};+++[A0A087WVV8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000479721};+++[A0A087WWQ1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000480416};+++[A0A087WY62_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000481542};+++[A0A087WZB6_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482516};+++[A0A087WZS8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482859};+++[A0A096LNW5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000485259};"]
[10109,"'ARPC2'",6445,7220,5570,6411.66666666667,"05132///Salmonella infection+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0005925///focal adhesion+++GO:0036195///muscle cell projection membrane+++GO:0035861///site of double-strand break+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031252///cell leading edge+++GO:0030027///lamellipodium+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0045202///synapse","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0070358///actin polymerization-dependent cell motility+++GO:0048013///ephrin receptor signaling pathway+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030041///actin filament polymerization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:0010592///positive regulation of lamellipodium assembly","actin related protein 2/3 complex subunit 2","[ARPC2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 2; AltName: Full=Arp2/3 complex 34 kDa subunit; Short=p34-ARC;+++[A0A024R408_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[C9JTV5_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[G5E9J0_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[G5E9S7_HUMAN|Unreviewed]SubName: Full=Actin related protein 2/3 complex, subunit 2, 34kDa, isoform CRA_e {ECO:0000313|EMBL:EAW70596.1}; SubName: Full=Actin-related protein 2/3 complex subunit 2 {ECO:0000313|Ensembl:ENSP00000412632};+++[H7C3F9_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[Q53R19_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};"]
[10110,"'SGK2'",7,4,2,4.33333333333333,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular","GO:0005524///ATP binding+++GO:0017081///chloride channel regulator activity+++GO:0005246///calcium channel regulator activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0015459///potassium channel regulator activity+++GO:0017080///sodium channel regulator activity","GO:0018105///peptidyl-serine phosphorylation+++GO:0034220///ion transmembrane transport+++GO:0001558///regulation of cell growth+++GO:0032411///positive regulation of transporter activity+++GO:0006468///protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0006979///response to oxidative stress+++GO:0042127///regulation of cell proliferation","SGK2, serine/threonine kinase 2","[SGK2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk2; EC=2.7.11.1; AltName: Full=Serum/glucocorticoid-regulated kinase 2;"]
[10111,"'RAD50'",932,625,782,779.666666666667,"03450///Non-homologous end-joining+++04218///Cellular senescence+++03440///Homologous recombination","H01344///Nijmegen syndrome","M00292///MRX complex+++M00291///MRN complex+++M00295///BRCA1-associated genome surveillance complex (BASC)",null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000790///nuclear chromatin+++GO:0030870///Mre11 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0008408///3'-5' exonuclease activity+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003691///double-stranded telomeric DNA binding+++GO:0004017///adenylate kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding+++GO:0043047///single-stranded telomeric DNA binding","GO:0016032///viral process+++GO:0033674///positive regulation of kinase activity+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0032206///positive regulation of telomere maintenance+++GO:0000019///regulation of mitotic recombination+++GO:0016233///telomere capping+++GO:0000723///telomere maintenance+++GO:0000722///telomere maintenance via recombination+++GO:0000729///DNA double-strand break processing+++GO:0007004///telomere maintenance via telomerase+++GO:0031860///telomeric 3' overhang formation+++GO:0032508///DNA duplex unwinding+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0000724///double-strand break repair via homologous recombination+++GO:1904354///negative regulation of telomere capping+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0006260///DNA replication+++GO:0070192///chromosome organization involved in meiotic cell cycle","RAD50 double strand break repair protein","[RAD50_HUMAN|Reviewed]RecName: Full=DNA repair protein RAD50; Short=hRAD50; EC=3.6.-.-;+++[A5D6Y3_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI40006.1}; Flags: Fragment;+++[C9JNH8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000389515}; Flags: Fragment;+++[E7EN38_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000400049}; Flags: Fragment;+++[E7ESD9_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000390971};+++[E9PM98_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000431225};+++[H7C0P8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396100}; Flags: Fragment;+++[H7C0V2_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396860}; Flags: Fragment;+++[Q32P42_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI08283.1}; Flags: Fragment;"]
[10112,"'KIF20A'",2,0,1,1,{"$nulls":4},"GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005819///spindle+++GO:0045171///intercellular bridge+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005871///kinesin complex","GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0003777///microtubule motor activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0007018///microtubule-based movement+++GO:0032465///regulation of cytokinesis+++GO:0061952///midbody abscission+++GO:0000281///mitotic cytokinesis+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0001578///microtubule bundle formation","kinesin family member 20A","[KI20A_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF20A; AltName: Full=GG10_2; AltName: Full=Mitotic kinesin-like protein 2; Short=MKlp2; AltName: Full=Rab6-interacting kinesin-like protein; AltName: Full=Rabkinesin-6;+++[D6R9E4_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000422928}; Flags: Fragment;+++[D6RBN1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000424056}; Flags: Fragment;+++[H0YAC9_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000426704}; Flags: Fragment;"]
[10113,"'PREB'",1181,1278,1192,1217,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005090///Sar guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0051020///GTPase binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0048208///COPII vesicle coating+++GO:0003400///regulation of COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0050790///regulation of catalytic activity+++GO:0009306///protein secretion+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0016192///vesicle-mediated transport","prolactin regulatory element binding","[PREB_HUMAN|Reviewed]RecName: Full=Prolactin regulatory element-binding protein; AltName: Full=Mammalian guanine nucleotide exchange factor mSec12;+++[A0A0F7RPZ8_HUMAN|Unreviewed]SubName: Full=Prometheus B {ECO:0000313|EMBL:CCP37866.1};+++[B5MC98_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000384032};+++[F8WCS5_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000416103};+++[H7BZX0_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000391894}; Flags: Fragment;+++[H7C0W3_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000397036}; Flags: Fragment;+++[H7C2N7_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000407036}; Flags: Fragment;+++[Q05DB2_HUMAN|Unreviewed]SubName: Full=PREB protein {ECO:0000313|EMBL:AAH16906.1}; SubName: Full=Prolactin regulatory element binding, isoform CRA_d {ECO:0000313|EMBL:EAX00629.1};"]
[10114,"'HIPK3'",996,619,872,829,"04218///Cellular senescence",{"$nulls":3},"GO:0005829///cytosol+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0018107///peptidyl-threonine phosphorylation+++GO:0009299///mRNA transcription+++GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation","homeodomain interacting protein kinase 3","[HIPK3_HUMAN|Reviewed]RecName: Full=Homeodomain-interacting protein kinase 3; EC=2.7.11.1; AltName: Full=Androgen receptor-interacting nuclear protein kinase; Short=ANPK; AltName: Full=Fas-interacting serine/threonine-protein kinase; Short=FIST; AltName: Full=Homolog of protein kinase YAK1;+++[A8KAE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75520 {ECO:0000313|EMBL:BAF85698.1};+++[E9PKD7_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 3 {ECO:0000313|Ensembl:ENSP00000433594}; Flags: Fragment;"]
[10116,"'FEM1B'",352,270,302,308,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005123///death receptor binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:2000001///regulation of DNA damage checkpoint+++GO:0016567///protein ubiquitination+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0002070///epithelial cell maturation+++GO:0043687///post-translational protein modification+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0006915///apoptotic process","fem-1 homolog B","[FEM1B_HUMAN|Reviewed]RecName: Full=Protein fem-1 homolog B; Short=FEM1b; AltName: Full=FEM1-beta; AltName: Full=Fem-1-like death receptor-binding protein alpha; AltName: Full=Fem-1-like in apoptotic pathway protein alpha; Short=F1A-alpha;+++[H3BT12_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000456968}; Flags: Fragment;+++[H3BTV3_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000457342}; Flags: Fragment;"]
[10117,"'ENAM'",0,2,1,1,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005788///endoplasmic reticulum lumen+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region","GO:0030345///structural constituent of tooth enamel+++GO:0005515///protein binding","GO:0042475///odontogenesis of dentin-containing tooth+++GO:0097186///amelogenesis+++GO:0031214///biomineral tissue development+++GO:0044267///cellular protein metabolic process+++GO:0022604///regulation of cell morphogenesis+++GO:0070175///positive regulation of enamel mineralization+++GO:0043687///post-translational protein modification+++GO:0036305///ameloblast differentiation","enamelin","[ENAM_HUMAN|Reviewed]RecName: Full=Enamelin; Flags: Precursor;+++[L8E8W5_HUMAN|Unreviewed]SubName: Full=Alternative protein ENAM {ECO:0000313|EMBL:CCQ43750.1};+++[Q8IWP4_HUMAN|Unreviewed]SubName: Full=Enamelin {ECO:0000313|EMBL:AAN87336.1};"]
[1012,"'CDH13'",344,355,272,323.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016342///catenin complex+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0009986///cell surface+++GO:0048471///perinuclear region of cytoplasm+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0098982///GABA-ergic synapse+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0055100///adiponectin binding+++GO:0071813///lipoprotein particle binding+++GO:0008092///cytoskeletal protein binding+++GO:0045296///cadherin binding+++GO:0030169///low-density lipoprotein particle binding","GO:0010033///response to organic substance+++GO:0007266///Rho protein signal transduction+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0034332///adherens junction organization+++GO:0030335///positive regulation of cell migration+++GO:0043542///endothelial cell migration+++GO:0043616///keratinocyte proliferation+++GO:0016601///Rac protein signal transduction+++GO:0050927///positive regulation of positive chemotaxis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0007043///cell-cell junction assembly+++GO:0030032///lamellipodium assembly+++GO:0030100///regulation of endocytosis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0002040///sprouting angiogenesis+++GO:0007155///cell adhesion+++GO:0000278///mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051668///localization within membrane","cadherin 13","[CAD13_HUMAN|Reviewed]RecName: Full=Cadherin-13; AltName: Full=Heart cadherin; Short=H-cadherin; AltName: Full=P105; AltName: Full=Truncated cadherin; Short=T-cad; Short=T-cadherin; Flags: Precursor;+++[B7Z3H7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50547, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH12213.1};+++[B7Z9B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52398, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH14247.1};+++[F5H7W7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000442225};+++[H3BQH4_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000455781};+++[H3BRL7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000456297};+++[H3BTF2_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457149};+++[H3BV21_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457914};"]
[10120,"'ACTR1B'",716,793,750,753,{"$nulls":4},"GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0034774///secretory granule lumen+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0005869///dynactin complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0015630///microtubule cytoskeleton+++GO:0005856///cytoskeleton","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","ARP1 actin related protein 1 homolog B","[ACTY_HUMAN|Reviewed]RecName: Full=Beta-centractin; AltName: Full=Actin-related protein 1B; Short=ARP1B;"]
[10121,"'ACTR1A'",3026,3131,2969,3042,{"$nulls":4},"GO:0005869///dynactin complex+++GO:0043209///myelin sheath+++GO:0005829///cytosol+++GO:0099738///cell cortex region+++GO:0030137///COPI-coated vesicle+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0002177///manchette+++GO:0015630///microtubule cytoskeleton+++GO:0005814///centriole+++GO:0070062///extracellular exosome+++GO:0005875///microtubule associated complex+++GO:0005815///microtubule organizing center+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0016192///vesicle-mediated transport+++GO:0007283///spermatogenesis+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport","ARP1 actin related protein 1 homolog A","[ACTZ_HUMAN|Reviewed]RecName: Full=Alpha-centractin; Short=Centractin; AltName: Full=ARP1; AltName: Full=Actin-RPV; AltName: Full=Centrosome-associated actin homolog;+++[A0A1B0GVS3_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000490634};+++[R4GMT0_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000473334};"]
[10123,"'ARL4C'",1454,1257,1072,1261,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding+++GO:0005525///GTP binding","GO:0032456///endocytic recycling+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","ADP ribosylation factor like GTPase 4C","[ARL4C_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4C; AltName: Full=ADP-ribosylation factor-like protein 7; AltName: Full=ADP-ribosylation factor-like protein LAK;+++[A0A024R4C5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4C, isoform CRA_a {ECO:0000313|EMBL:EAW71074.1};"]
[10124,"'ARL4A'",263,243.89,241.97,249.62,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","ADP ribosylation factor like GTPase 4A","[ARL4A_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4A;+++[A0A024R9Z2_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4A, isoform CRA_a {ECO:0000313|EMBL:EAW93652.1};+++[C9J7Q9_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 4A {ECO:0000313|Ensembl:ENSP00000397651}; Flags: Fragment;"]
[10125,"'RASGRP1'",192,183,152,175.666666666667,"05200///Pathways in cancer+++04660///T cell receptor signaling pathway+++04611///Platelet activation+++04014///Ras signaling pathway+++04010///MAPK signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0042629///mast cell granule+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0019992///diacylglycerol binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005096///GTPase activator activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031210///phosphatidylcholine binding+++GO:0042803///protein homodimerization activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1900744///regulation of p38MAPK cascade+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007264///small GTPase mediated signal transduction+++GO:1902715///positive regulation of interferon-gamma secretion+++GO:0090630///activation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0007165///signal transduction+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001816///cytokine production+++GO:0043303///mast cell degranulation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0047496///vesicle transport along microtubule+++GO:0043087///regulation of GTPase activity+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0007265///Ras protein signal transduction+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0000165///MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0032252///secretory granule localization+++GO:1900274///regulation of phospholipase C activity+++GO:0030154///cell differentiation+++GO:0032816///positive regulation of natural killer cell activation","RAS guanyl releasing protein 1","[GRP1_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 1; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor II; Short=CalDAG-GEFII; AltName: Full=Ras guanyl-releasing protein;+++[B2RA89_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94771, highly similar to Homo sapiens RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), mRNA {ECO:0000313|EMBL:BAG36786.1};+++[F5H514_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000444762};+++[H0YKM0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452859};+++[H0YKP8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452892}; Flags: Fragment;+++[H0YMF3_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453583}; Flags: Fragment;+++[H0YMT0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453729}; Flags: Fragment;+++[H0YN83_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453905}; Flags: Fragment;+++[H0YNG8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454005}; Flags: Fragment;+++[H0YNK9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454053}; Flags: Fragment;"]
[10126,"'DNAL4'",236,245,249,243.333333333333,"05016///Huntington's disease",{"$nulls":3},"GO:0005874///microtubule+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0030286///dynein complex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005929///cilium","GO:0051959///dynein light intermediate chain binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0005515///protein binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0045505///dynein intermediate chain binding","GO:0007018///microtubule-based movement+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed+++GO:0007017///microtubule-based process","dynein axonemal light chain 4","[DNAL4_HUMAN|Reviewed]RecName: Full=Dynein light chain 4, axonemal;+++[B0QXZ5_HUMAN|Unreviewed]RecName: Full=Dynein light chain {ECO:0000256|RuleBase:RU365010};"]
[10127,"'ZNF263'",392,343,356,363.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger protein 263","[ZN263_HUMAN|Reviewed]RecName: Full=Zinc finger protein 263; AltName: Full=Zinc finger protein FPM315; AltName: Full=Zinc finger protein with KRAB and SCAN domains 12;+++[B4DI05_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57935, highly similar to Zinc finger protein 263 {ECO:0000313|EMBL:BAG58317.1};+++[D3DUC1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263, isoform CRA_a {ECO:0000313|EMBL:EAW85380.1};+++[I3L0N0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000458214}; Flags: Fragment;+++[I3L2X3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000459998};+++[I3L393_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000460278};+++[I3L4C4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461146}; Flags: Fragment;+++[I3L538_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461755}; Flags: Fragment;+++[I3NI39_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461861}; Flags: Fragment;"]
[10128,"'LRPPRC'",1225,861,1085,1057,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01354///Leigh syndrome+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0000794///condensed nuclear chromosome+++GO:1990904///ribonucleoprotein complex+++GO:0005874///microtubule+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005640///nuclear outer membrane+++GO:0005634///nucleus+++GO:0042645///mitochondrial nucleoid+++GO:0005637///nuclear inner membrane+++GO:0005856///cytoskeleton","GO:0008017///microtubule binding+++GO:0048487///beta-tubulin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0051015///actin filament binding+++GO:0003697///single-stranded DNA binding","GO:0070129///regulation of mitochondrial translation+++GO:0051028///mRNA transport+++GO:0000961///negative regulation of mitochondrial RNA catabolic process+++GO:0047497///mitochondrion transport along microtubule","leucine rich pentatricopeptide repeat containing","[LPPRC_HUMAN|Reviewed]RecName: Full=Leucine-rich PPR motif-containing protein, mitochondrial; AltName: Full=130 kDa leucine-rich protein; Short=LRP 130; AltName: Full=GP130; Flags: Precursor;+++[A0A0C4DG06_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386234};+++[B8ZZ38_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386562};+++[C9JCA9_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000403637}; Flags: Fragment;+++[E5KNY5_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR-motif containing {ECO:0000313|EMBL:EAX00284.1}; SubName: Full=Mitochondrial leucine-rich PPR motif-containing protein {ECO:0000313|EMBL:ADP90894.1};+++[H7C3W8_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000414207}; Flags: Fragment;"]
[10129,"'FRY'",234,155,143,177.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0004857///enzyme inhibitor activity","GO:0000902///cell morphogenesis+++GO:0043086///negative regulation of catalytic activity+++GO:0031175///neuron projection development+++GO:1904428///negative regulation of tubulin deacetylation","FRY microtubule binding protein","[FRY_HUMAN|Reviewed]RecName: Full=Protein furry homolog;+++[A0A024RDQ1_HUMAN|Unreviewed]SubName: Full=Furry homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAX08493.1};+++[A0A0C4DFX2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000369600};+++[A0A286YFA9_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000493189};+++[A0A2R8Y5V8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494761};+++[A0A2R8Y7Y8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000496501}; Flags: Fragment;+++[A0A2R8YCY2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494080};+++[B1ALA1_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000398010}; Flags: Fragment;+++[H0YE00_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000434694}; Flags: Fragment;+++[L8EB55_HUMAN|Unreviewed]SubName: Full=Alternative protein FRY {ECO:0000313|EMBL:CCQ43703.1};+++[Q96KW3_HUMAN|Unreviewed]SubName: Full=214K23.2.1 (Novel protein, isoform 1) {ECO:0000313|EMBL:CAC94765.1}; Flags: Fragment;+++[Q96KW4_HUMAN|Unreviewed]SubName: Full=214K23.2.2 (Novel protein, isoform 2) {ECO:0000313|EMBL:CAC94764.1}; Flags: Fragment;"]
[1013,"'CDH15'",7,12,6,8.33333333333333,"04514///Cell adhesion molecules (CAMs)","H00773///Autosomal dominant mental retardation",null,null,"GO:0005901///caveola+++GO:0031594///neuromuscular junction+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0016342///catenin complex","GO:0008092///cytoskeletal protein binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0003674///molecular_function+++GO:0042803///protein homodimerization activity","GO:0042060///wound healing+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:1902910///positive regulation of melanosome transport+++GO:0050896///response to stimulus+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0022405///hair cycle process+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0042493///response to drug+++GO:0007155///cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0007601///visual perception+++GO:0031424///keratinization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051796///negative regulation of timing of catagen+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0007043///cell-cell junction assembly+++GO:0001895///retina homeostasis+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation","cadherin 15","[CAD15_HUMAN|Reviewed]RecName: Full=Cadherin-15; AltName: Full=Cadherin-14; AltName: Full=Muscle cadherin; Short=M-cadherin; Flags: Precursor;+++[J3KRQ1_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000462111}; Flags: Fragment;+++[J3QKW6_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463267}; Flags: Fragment;+++[J3QL41_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463364}; Flags: Fragment;+++[J3QL75_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463415}; Flags: Fragment;+++[J3QR34_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464021};+++[J3QR60_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464058}; Flags: Fragment;"]
[10130,"'PDIA6'",7848,8078,6873,7599.66666666667,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0042470///melanosome+++GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0003756///protein disulfide isomerase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0006457///protein folding+++GO:0044267///cellular protein metabolic process+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process","protein disulfide isomerase family A member 6","[PDIA6_HUMAN|Reviewed]RecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1 {ECO:0000269|PubMed:12204115, ECO:0000269|PubMed:15466936}; AltName: Full=Endoplasmic reticulum protein 5; Short=ER protein 5; Short=ERp5; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor;+++[C9JNG5_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A6 {ECO:0000313|Ensembl:ENSP00000389558}; Flags: Fragment;"]
[10131,"'TRAP1'",1371,1325,1419,1371.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005759///mitochondrial matrix","GO:0051082///unfolded protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003723///RNA binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0061077///chaperone-mediated protein folding+++GO:0009386///translational attenuation+++GO:1901856///negative regulation of cellular respiration+++GO:0006950///response to stress+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process","TNF receptor associated protein 1","[TRAP1_HUMAN|Reviewed]RecName: Full=Heat shock protein 75 kDa, mitochondrial; Short=HSP 75; AltName: Full=TNFR-associated protein 1; AltName: Full=Tumor necrosis factor type 1 receptor-associated protein; Short=TRAP-1; Flags: Precursor;+++[A0A140VJY2_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 209 {ECO:0000313|EMBL:AEE61119.1};+++[I3L0K7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458166}; SubName: Full=TNF receptor-associated protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW85339.1};+++[I3L0P6_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458244}; Flags: Fragment;+++[I3L239_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459354}; Flags: Fragment;+++[I3L253_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459385}; Flags: Fragment;+++[I3L2D5_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459585}; Flags: Fragment;+++[I3L3L4_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000460545};+++[I3L4L7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000461354};+++[K0A7K7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:AFS69159.1}; Flags: Fragment;+++[Q53FS6_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 variant {ECO:0000313|EMBL:BAD96925.1}; Flags: Fragment;+++[Q5CAQ4_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:CAI64498.1}; SubName: Full=cDNA FLJ33058 fis, clone TRACH1000181, highly similar to Heat shock protein 75 kDa, mitochondrial {ECO:0000313|EMBL:BAG51942.1};+++[Q9BV61_HUMAN|Unreviewed]SubName: Full=TRAP1 protein {ECO:0000313|EMBL:AAH01455.2}; Flags: Fragment;"]
[10133,"'OPTN'",1617,1536,1344,1499,"04137///Mitophagy - animal","H00612///Primary open angle glaucoma+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0055037///recycling endosome+++GO:0005802///trans-Golgi network+++GO:0005776///autophagosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005634///nucleus","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0030674///protein binding, bridging+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding","GO:0045087///innate immune response+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016192///vesicle-mediated transport+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007030///Golgi organization+++GO:0090161///Golgi ribbon formation+++GO:1904417///positive regulation of xenophagy+++GO:0006914///autophagy+++GO:0001920///negative regulation of receptor recycling+++GO:0008219///cell death+++GO:0034067///protein localization to Golgi apparatus+++GO:0034620///cellular response to unfolded protein+++GO:0002376///immune system process+++GO:0050829///defense response to Gram-negative bacterium+++GO:0034613///cellular protein localization+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0010508///positive regulation of autophagy+++GO:0007165///signal transduction","optineurin","[OPTN_HUMAN|Reviewed]RecName: Full=Optineurin; AltName: Full=E3-14.7K-interacting protein; AltName: Full=FIP-2; AltName: Full=Huntingtin yeast partner L; AltName: Full=Huntingtin-interacting protein 7; Short=HIP-7; AltName: Full=Huntingtin-interacting protein L; AltName: Full=NEMO-related protein; AltName: Full=Optic neuropathy-inducing protein; AltName: Full=Transcription factor IIIA-interacting protein; Short=TFIIIA-IntP;+++[A0A087WY28_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000481473}; Flags: Fragment;+++[A0A087X2G2_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000484961};+++[A0A0S2Z500_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 1 {ECO:0000313|EMBL:ALQ33960.1}; Flags: Fragment;+++[A0A0S2Z5I6_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 3 {ECO:0000313|EMBL:ALQ33961.1};+++[H7C1H4_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000400356}; Flags: Fragment;+++[X6RKL2_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 4 {ECO:0000313|EMBL:ALQ33962.1};"]
[10134,"'BCAP31'",2879,3173,2837,2963,"05165///Human papillomavirus infection+++04141///Protein processing in endoplasmic reticulum","H00849///Creatine deficiency syndrome+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0030136///clathrin-coated vesicle+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0032580///Golgi cisterna membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0005784///Sec61 translocon complex+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005811///lipid droplet+++GO:0005887///integral component of plasma membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0042288///MHC class I protein binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0015031///protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007283///spermatogenesis+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0006886///intracellular protein transport+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:0016192///vesicle-mediated transport+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0006915///apoptotic process","B cell receptor associated protein 31","[BAP31_HUMAN|Reviewed]RecName: Full=B-cell receptor-associated protein 31; Short=BCR-associated protein 31; Short=Bap31; AltName: Full=6C6-AG tumor-associated antigen; AltName: Full=Protein CDM; AltName: Full=p28;+++[A0A2R8Y5M6_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000494936};+++[C9J0M4_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000400345}; Flags: Fragment;+++[C9JM14_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000402342}; Flags: Fragment;+++[C9JMD7_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000389740}; Flags: Fragment;+++[C9JQ75_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000409888}; Flags: Fragment;+++[C9JSP1_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000394270}; Flags: Fragment;"]
[10135,"'NAMPT'",388,245,296,309.666666666667,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways+++04621///NOD-like receptor signaling pathway",null,null,"R01271///nicotinamide-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase   Nicotinamide D-ribonucleotide + Diphosphate <=> Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate","GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0005615///extracellular space","GO:0042803///protein homodimerization activity+++GO:0008144///drug binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047280///nicotinamide phosphoribosyltransferase activity+++GO:0042802///identical protein binding+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0005125///cytokine activity","GO:0014070///response to organic cyclic compound+++GO:0009435///NAD biosynthetic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0060612///adipose tissue development+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0001774///microglial cell activation+++GO:0008284///positive regulation of cell proliferation+++GO:1905377///response to D-galactose+++GO:0070997///neuron death+++GO:0032922///circadian regulation of gene expression+++GO:0007568///aging+++GO:0010469///regulation of signaling receptor activity+++GO:1904646///cellular response to amyloid-beta+++GO:0007565///female pregnancy+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0010507///negative regulation of autophagy+++GO:0007267///cell-cell signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0007623///circadian rhythm+++GO:0048511///rhythmic process+++GO:0034356///NAD biosynthesis via nicotinamide riboside salvage pathway+++GO:0014916///regulation of lung blood pressure","nicotinamide phosphoribosyltransferase","[NAMPT_HUMAN|Reviewed]RecName: Full=Nicotinamide phosphoribosyltransferase; Short=NAmPRTase; Short=Nampt; EC=2.4.2.12; AltName: Full=Pre-B-cell colony-enhancing factor 1; Short=Pre-B cell-enhancing factor; AltName: Full=Visfatin;+++[A0A024R718_HUMAN|Unreviewed]SubName: Full=Pre-B-cell colony enhancing factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW83384.1};+++[A0A0C4DFS8_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000346242};+++[C9JF35_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390896}; Flags: Fragment;+++[C9JG65_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390591}; Flags: Fragment;"]
[10136,"'CELA3A'",0,0,1,0.333333333333333,"04974///Protein digestion and absorption+++04972///Pancreatic secretion",{"$nulls":3},"GO:0005615///extracellular space","GO:0016787///hydrolase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis","chymotrypsin like elastase family member 3A","[CEL3A_HUMAN|Reviewed]RecName: Full=Chymotrypsin-like elastase family member 3A; EC=3.4.21.70; AltName: Full=Elastase IIIA; AltName: Full=Elastase-3A; AltName: Full=Protease E; Flags: Precursor;+++[B1AQ52_HUMAN|Unreviewed]SubName: Full=Chymotrypsin-like elastase family member 3A {ECO:0000313|Ensembl:ENSP00000363795};+++[B1AQ55_HUMAN|Unreviewed]SubName: Full=Chymotrypsin-like elastase family member 3A {ECO:0000313|Ensembl:ENSP00000383130}; Flags: Fragment;+++[Q96QL8_HUMAN|Unreviewed]SubName: Full=Elastase 3A, pancreatic {ECO:0000313|EMBL:AAH08383.1};"]
[10137,"'RBM12'",1269.35,897.87,1082,1083.07333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding",null,"RNA binding motif protein 12","[RBM12_HUMAN|Reviewed]RecName: Full=RNA-binding protein 12; AltName: Full=RNA-binding motif protein 12; AltName: Full=SH3/WW domain anchor protein in the nucleus; Short=SWAN;+++[A6PVI0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000392642}; Flags: Fragment;+++[A6PVI1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411692}; Flags: Fragment;+++[Q5JX62_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411036}; Flags: Fragment;"]
[10138,"'YAF2'",152,165,166,161,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity","GO:0070317///negative regulation of G0 to G1 transition+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","YY1 associated factor 2","[YAF2_HUMAN|Reviewed]RecName: Full=YY1-associated factor 2;+++[A0A0B4J255_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447863};+++[B4DJQ9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57510, highly similar to YY1-associated factor 2 {ECO:0000313|EMBL:BAG58921.1};+++[F8VRE5_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448533};+++[F8VZR2_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447686}; Flags: Fragment;+++[F8W0B9_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447217};+++[G3V1X5_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_g {ECO:0000313|EMBL:EAW57840.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448291};+++[G3V212_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_b {ECO:0000313|EMBL:EAW57835.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450097};+++[G3V219_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_d {ECO:0000313|EMBL:EAW57837.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450394};"]
[10139,"'ARFRP1'",310,355,319,328,"04060///Cytokine-cytokine receptor interaction","H00108///Autoimmune lymphoproliferative syndromes (ALPS)",null,null,"GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032588///trans-Golgi network membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:0007369///gastrulation+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007165///signal transduction+++GO:0033365///protein localization to organelle+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0034067///protein localization to Golgi apparatus+++GO:0006886///intracellular protein transport","ADP ribosylation factor related protein 1","[ARFRP_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-related protein 1; Short=ARF-related protein 1; Short=ARP;+++[B7ZKY8_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1 {ECO:0000313|EMBL:AAI43468.1};+++[H0UI96_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW75236.1};"]
[10140,"'TOB1'",1040,910,1067,1005.66666666667,"03018///RNA degradation",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex","GO:0005515///protein binding+++GO:0046332///SMAD binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0003714///transcription corepressor activity+++GO:0030971///receptor tyrosine kinase binding","GO:0060212///negative regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0009967///positive regulation of signal transduction+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0017148///negative regulation of translation+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0008285///negative regulation of cell proliferation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0010468///regulation of gene expression+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening","transducer of ERBB2, 1","[TOB1_HUMAN|Reviewed]RecName: Full=Protein Tob1; AltName: Full=Transducer of erbB-2 1;"]
[101410538,"'MMP24OS'",5346,6100,5885,5777,{"$nulls":7},"MMP24 opposite strand","[MMPOS_HUMAN|Reviewed]RecName: Full=Protein MMP24OS {ECO:0000305}; AltName: Full=MMP24 opposite strand {ECO:0000312|HGNC:HGNC:44421};"]
[10142,"'AKAP9'",1187.98,974,972,1044.66,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00720///Long QT syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0099147///extrinsic component of postsynaptic density membrane+++GO:0043025///neuronal cell body+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0044307///dendritic branch+++GO:0005795///Golgi stack+++GO:0097060///synaptic membrane+++GO:0005815///microtubule organizing center+++GO:0005801///cis-Golgi network+++GO:0008076///voltage-gated potassium channel complex+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0005813///centrosome","GO:0015459///potassium channel regulator activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0016301///kinase activity+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0034237///protein kinase A regulatory subunit binding","GO:0051602///response to electrical stimulus+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0007165///signal transduction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0016310///phosphorylation+++GO:1903358///regulation of Golgi organization+++GO:0071320///cellular response to cAMP+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0060306///regulation of membrane repolarization+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:0007268///chemical synaptic transmission+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0051661///maintenance of centrosome location+++GO:0031116///positive regulation of microtubule polymerization+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007020///microtubule nucleation+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0000086///G2/M transition of mitotic cell cycle","A-kinase anchoring protein 9","[AKAP9_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 9; Short=AKAP-9; AltName: Full=A-kinase anchor protein 350 kDa; Short=AKAP 350; Short=hgAKAP 350; AltName: Full=A-kinase anchor protein 450 kDa; Short=AKAP 450; AltName: Full=AKAP 120-like protein; AltName: Full=Centrosome- and Golgi-localized PKN-associated protein {ECO:0000303|PubMed:10358086}; Short=CG-NAP {ECO:0000303|PubMed:10358086}; AltName: Full=Protein hyperion {ECO:0000303|Ref.4}; AltName: Full=Protein kinase A-anchoring protein 9; Short=PRKA9; AltName: Full=Protein yotiao {ECO:0000303|PubMed:9482789};+++[A0A087WX84_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000480807};+++[A0A0A0MRE9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000350813};+++[A0A0A0MRF6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000351922};+++[A0A2R8Y590_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000494626}; Flags: Fragment;+++[A4D1E4_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9 {ECO:0000313|EMBL:EAL24158.1};+++[H0Y6Q0_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000406937}; Flags: Fragment;+++[H7BYL6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378042}; Flags: Fragment;+++[H7BZV6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000391704}; Flags: Fragment;+++[Q5GIA7_HUMAN|Unreviewed]SubName: Full=Antigen MU-RMS-40.16A {ECO:0000313|EMBL:AAT44400.1}; Flags: Fragment;+++[Q6PJH3_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9, isoform CRA_c {ECO:0000313|EMBL:EAW76862.1}; SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378065}; SubName: Full=AKAP9 protein {ECO:0000313|EMBL:AAH15533.1};"]
[10144,"'FAM13A'",1138,785,1515,1146,"04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","family with sequence similarity 13 member A","[FA13A_HUMAN|Reviewed]RecName: Full=Protein FAM13A;+++[A0A2X0SFT1_HUMAN|Unreviewed]SubName: Full=FAM13A {ECO:0000313|EMBL:SPT35754.1}; Flags: Fragment;+++[D6RCC1_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000423800};+++[D6RD35_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000427077};+++[D6RFM4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000426517};+++[D6RGE4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421269}; Flags: Fragment;+++[D6RIY4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000425784};+++[E9PGM7_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421914};+++[L0R4X6_HUMAN|Unreviewed]SubName: Full=Alternative protein FAM13A {ECO:0000313|EMBL:CCO13728.1};+++[Q6P521_HUMAN|Unreviewed]SubName: Full=FAM13A protein {ECO:0000313|EMBL:AAH63126.1}; SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000422345};"]
[10146,"'G3BP1'",913,705,787,801.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0043204///perikaryon+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0010494///cytoplasmic stress granule","GO:0004518///nuclease activity+++GO:0003676///nucleic acid binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0004519///endonuclease activity+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0003729///mRNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding","GO:0034063///stress granule assembly+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0032508///DNA duplex unwinding+++GO:0007265///Ras protein signal transduction","G3BP stress granule assembly factor 1","[G3BP1_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12 {ECO:0000269|PubMed:9889278}; EC=3.6.4.13 {ECO:0000269|PubMed:9889278}; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1;+++[E5RH00_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430045};+++[E5RH42_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429920}; Flags: Fragment;+++[E5RI46_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000428469}; Flags: Fragment;+++[E5RIF8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430738}; Flags: Fragment;+++[E5RIZ6_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429250}; Flags: Fragment;+++[E5RJU8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430480};+++[Q32P45_HUMAN|Unreviewed]SubName: Full=GTPase activating protein (SH3 domain) binding protein 1 {ECO:0000313|EMBL:AAI08279.1};+++[Q5U0Q1_HUMAN|Unreviewed]SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein {ECO:0000313|EMBL:AAV38191.1}; SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW61659.1}; SubName: Full=cDNA, FLJ92947, Homo sapiens Ras-GTPase-activating protein SH3-domain-bindingprotein (G3BP), mRNA {ECO:0000313|EMBL:BAG35467.1};+++[Q6FI03_HUMAN|Unreviewed]SubName: Full=G3BP protein {ECO:0000313|EMBL:CAG38772.1};+++[Q6ZP53_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1 {ECO:0000313|EMBL:BAC85272.1};"]
[10147,"'SUGP2'",1653.99,1427.01,1737.77,1606.25666666667,{"$nulls":4},"GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0006396///RNA processing+++GO:0008380///RNA splicing","SURP and G-patch domain containing 2","[SUGP2_HUMAN|Reviewed]RecName: Full=SURP and G-patch domain-containing protein 2; AltName: Full=Arginine/serine-rich-splicing factor 14; AltName: Full=Splicing factor, arginine/serine-rich 14;+++[A0A024R7K0_HUMAN|Unreviewed]SubName: Full=Splicing factor, arginine/serine-rich 14, isoform CRA_a {ECO:0000313|EMBL:EAW84768.1};+++[A8K5G0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76836, highly similar to Homo sapiens splicing factor, arginine/serine-rich 14 (SFRS14), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83964.1};+++[M0R065_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000471042}; Flags: Fragment;+++[M0R1Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472183}; Flags: Fragment;+++[M0R216_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472244}; Flags: Fragment;+++[M0R2Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472878}; Flags: Fragment;+++[M0R2Z9_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472914};+++[M0R3F6_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000473187};"]
[10148,"'EBI3'",16,16,23,18.3333333333333,{"$nulls":4},"GO:0070110///ciliary neurotrophic factor receptor complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043235///receptor complex+++GO:0097059///CNTFR-CLCF1 complex","GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0045523///interleukin-27 receptor binding+++GO:0019955///cytokine binding","GO:0006959///humoral immune response+++GO:0042088///T-helper 1 type immune response+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0070757///interleukin-35-mediated signaling pathway+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0042098///T cell proliferation","Epstein-Barr virus induced 3","[IL27B_HUMAN|Reviewed]RecName: Full=Interleukin-27 subunit beta; Short=IL-27 subunit beta; Short=IL-27B; AltName: Full=Epstein-Barr virus-induced gene 3 protein; Short=EBV-induced gene 3 protein; Flags: Precursor;"]
[10149,"'ADGRG2'",8,7,9,8,null,"H01033///Congenital bilateral absence of vas deferens",null,null,"GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome","GO:0004930///G protein-coupled receptor activity+++GO:0004888///transmembrane signaling receptor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007166///cell surface receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor G2","[AGRG2_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor G2 {ECO:0000303|PubMed:25713288}; AltName: Full=G-protein coupled receptor 64; AltName: Full=Human epididymis-specific protein 6; Short=He6; Flags: Precursor;+++[A0A024RC03_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64, isoform CRA_a {ECO:0000313|EMBL:EAW98954.1};+++[A8K4P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77493, highly similar to Homo sapiens G protein-coupled receptor 64 (GPR64), mRNA {ECO:0000313|EMBL:BAF83701.1};+++[Q14CE1_HUMAN|Unreviewed]SubName: Full=GPR64 protein {ECO:0000313|EMBL:AAI13979.1};+++[Q499H0_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64 {ECO:0000313|EMBL:AAH99901.1};"]
[10150,"'MBNL2'",2650,1783,2053,2162,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","muscleblind like splicing regulator 2","[MBNL2_HUMAN|Reviewed]RecName: Full=Muscleblind-like protein 2; AltName: Full=Muscleblind-like protein 1; AltName: Full=Muscleblind-like protein-like; AltName: Full=Muscleblind-like protein-like 39;+++[A0PJJ3_HUMAN|Unreviewed]SubName: Full=MBNL2 protein {ECO:0000313|EMBL:AAH32426.1}; Flags: Fragment;+++[A2A3S3_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAX08968.1}; SubName: Full=cDNA FLJ76890, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF84416.1}; SubName: Full=cDNA, FLJ79493, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF98735.1};+++[O95205_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAX08969.1}; SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000432422}; SubName: Full=Zinc finger protein {ECO:0000313|EMBL:AAC67242.1};+++[Q5JSC0_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000404202}; Flags: Fragment;"]
[10152,"'ABI2'",1069.98,856.99,1028.25,985.073333333333,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0032433///filopodium tip+++GO:0030054///cell junction+++GO:0031209///SCAR complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030175///filopodium+++GO:0005634///nucleus+++GO:0005912///adherens junction","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0017124///SH3 domain binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0048365///Rac GTPase binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0003674///molecular_function+++GO:0070064///proline-rich region binding","GO:0016032///viral process+++GO:0007399///nervous system development+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation+++GO:0008150///biological_process+++GO:0008154///actin polymerization or depolymerization+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0016601///Rac protein signal transduction+++GO:0007010///cytoskeleton organization","abl interactor 2","[ABI2_HUMAN|Reviewed]RecName: Full=Abl interactor 2 {ECO:0000303|Ref.16}; AltName: Full=Abelson interactor 2 {ECO:0000303|Ref.16}; Short=Abi-2 {ECO:0000303|PubMed:7590236}; AltName: Full=Abl-binding protein 3; Short=AblBP3; AltName: Full=Arg-binding protein 1 {ECO:0000303|PubMed:8649853}; Short=ArgBP1 {ECO:0000303|PubMed:8649853};+++[A0A0C4DG21_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000391433};+++[B7Z836_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51162, highly similar to Abl interactor 2 {ECO:0000313|EMBL:BAH13822.1};+++[E7EP65_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000414703}; Flags: Fragment;+++[E7EUA1_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000398487};+++[E7EW77_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000396249};+++[E9PEZ7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408898};+++[F8WAL6_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000261018};+++[F8WAQ3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000410509}; Flags: Fragment;+++[F8WAU3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405255};+++[F8WAZ8_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000397850};+++[F8WBL5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405801};+++[F8WCD7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000399040};+++[F8WEB9_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408334};+++[H0Y6B5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000404352}; Flags: Fragment;+++[H7C3Q7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000413375}; Flags: Fragment;+++[Q13802_HUMAN|Unreviewed]SubName: Full=ArgBPIB protein {ECO:0000313|EMBL:CAA64980.1};+++[Q53RS4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14935.1}; Flags: Fragment;+++[Q53SH3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14675.1}; Flags: Fragment;"]
[10153,"'CEBPZ'",367,291,246,301.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","CCAAT enhancer binding protein zeta","[CEBPZ_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein zeta; AltName: Full=CCAAT-box-binding transcription factor; Short=CBF; Short=CCAAT-binding factor;+++[C9J9W7_HUMAN|Unreviewed]SubName: Full=CCAAT/enhancer-binding protein zeta {ECO:0000313|Ensembl:ENSP00000391881}; Flags: Fragment;"]
[10154,"'PLXNC1'",6,4,13,7.66666666666667,"04360///Axon guidance","H00537///Nephronophthisis",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0002116///semaphorin receptor complex","GO:0017154///semaphorin receptor activity+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0007162///negative regulation of cell adhesion+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:0008360///regulation of cell shape+++GO:0030334///regulation of cell migration+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007165///signal transduction+++GO:0050772///positive regulation of axonogenesis+++GO:0043087///regulation of GTPase activity+++GO:0007155///cell adhesion","plexin C1","[PLXC1_HUMAN|Reviewed]RecName: Full=Plexin-C1; AltName: Full=Virus-encoded semaphorin protein receptor; AltName: CD_antigen=CD232; Flags: Precursor;+++[B4DHQ7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60256, highly similar to Plexin-C1 {ECO:0000313|EMBL:BAG58219.1};+++[F5H3A2_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000439225};+++[F8VUW4_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447843}; Flags: Fragment;+++[F8W095_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447625}; Flags: Fragment;+++[F8W1K6_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000446781};"]
[10155,"'TRIM28'",4363,5095,4612,4690,{"$nulls":4},"GO:0005720///nuclear heterochromatin+++GO:0000785///chromatin+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005719///nuclear euchromatin","GO:0043565///sequence-specific DNA binding+++GO:0035851///Krueppel-associated box domain binding+++GO:1990841///promoter-specific chromatin binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0070087///chromo shadow domain binding+++GO:0003714///transcription corepressor activity+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0007566///embryo implantation+++GO:0016567///protein ubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0060669///embryonic placenta morphogenesis+++GO:1901536///negative regulation of DNA demethylation+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0060028///convergent extension involved in axis elongation+++GO:0006281///DNA repair+++GO:0007265///Ras protein signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0051259///protein complex oligomerization+++GO:1902187///negative regulation of viral release from host cell+++GO:0045087///innate immune response+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:2000653///regulation of genetic imprinting+++GO:0042307///positive regulation of protein import into nucleus+++GO:0006325///chromatin organization+++GO:0016925///protein sumoylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045739///positive regulation of DNA repair+++GO:0006468///protein phosphorylation+++GO:0043045///DNA methylation involved in embryo development+++GO:0016032///viral process+++GO:0043388///positive regulation of DNA binding","tripartite motif containing 28","[TIF1B_HUMAN|Reviewed]RecName: Full=Transcription intermediary factor 1-beta; Short=TIF1-beta; AltName: Full=E3 SUMO-protein ligase TRIM28; EC=2.3.2.27; AltName: Full=KRAB-associated protein 1; Short=KAP-1; AltName: Full=KRAB-interacting protein 1; Short=KRIP-1; AltName: Full=Nuclear corepressor KAP-1; AltName: Full=RING finger protein 96; AltName: Full=RING-type E3 ubiquitin transferase TIF1-beta {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 28;+++[M0QZE6_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000470503}; Flags: Fragment;+++[M0R0K9_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000471303}; Flags: Fragment;+++[M0R2I3_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000472586}; Flags: Fragment;+++[M0R3C0_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000473126}; Flags: Fragment;"]
[10156,"'RASA4'",330.93,373.3,300.95,335.06,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding+++GO:0005543///phospholipid binding","GO:0071277///cellular response to calcium ion+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0034260///negative regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0007165///signal transduction","RAS p21 protein activator 4","[RASL2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4; AltName: Full=Calcium-promoted Ras inactivator; AltName: Full=Ras p21 protein activator 4; AltName: Full=RasGAP-activating-like protein 2;+++[A0A087WUJ9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000478719};+++[B7ZL55_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI43585.1};+++[E5RGQ8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428732}; Flags: Fragment;+++[E5RID2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428448}; Flags: Fragment;+++[E5RK78_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430418}; Flags: Fragment;+++[E7ERK1_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000417395};+++[H0YB35_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428605}; Flags: Fragment;+++[H0YBU2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430337}; Flags: Fragment;+++[Q2NL74_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI10874.1};"]
[10157,"'AASS'",372,271,416.62,353.206666666667,"01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00310///Lysine degradation+++01100///Metabolic pathways","H01242///Saccharopinuria+++H00188///Hyperlysinemia","M00032///Lysine degradation, lysine => saccharopine => acetoacetyl-CoA","R02313///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase; N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADH + H++++R00716///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADPH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0047130///saccharopine dehydrogenase (NADP+, L-lysine-forming) activity+++GO:0047131///saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity+++GO:0004753///saccharopine dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0003824///catalytic activity","GO:0019878///lysine biosynthetic process via aminoadipic acid+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine+++GO:0051262///protein tetramerization+++GO:0006554///lysine catabolic process+++GO:0019477///L-lysine catabolic process+++GO:0055114///oxidation-reduction process+++GO:0008152///metabolic process","aminoadipate-semialdehyde synthase","[AASS_HUMAN|Reviewed]RecName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial; AltName: Full=LKR/SDH; Includes: RecName: Full=Lysine ketoglutarate reductase; Short=LKR; Short=LOR; EC=1.5.1.8; Includes: RecName: Full=Saccharopine dehydrogenase; Short=SDH; EC=1.5.1.9; Flags: Precursor;+++[A4D0W4_HUMAN|Unreviewed]SubName: Full=Aminoadipate-semialdehyde synthase, isoform CRA_a {ECO:0000313|EMBL:EAW83564.1};+++[F8WAH1_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000351834};+++[F8WE53_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000414001};+++[H7C0C6_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000394180}; Flags: Fragment;"]
[10158,"'PDZK1IP1'",13,10,25,16,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane",null,null,"PDZK1 interacting protein 1","[PDZ1I_HUMAN|Reviewed]RecName: Full=PDZK1-interacting protein 1; AltName: Full=17 kDa membrane-associated protein; AltName: Full=Protein DD96;"]
[10159,"'ATP6AP2'",2063,1862,1740,1888.33333333333,"04614///Renin-angiotensin system","H00658///Syndromic X-linked mental retardation",null,null,"GO:0044297///cell body+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0009897///external side of plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection","GO:0038023///signaling receptor activity+++GO:0019899///enzyme binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0060323///head morphogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021903///rostrocaudal neural tube patterning+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0048069///eye pigmentation+++GO:0002003///angiotensin maturation+++GO:0043408///regulation of MAPK cascade","ATPase H+ transporting accessory protein 2","[RENR_HUMAN|Reviewed]RecName: Full=Renin receptor; AltName: Full=ATPase H(+)-transporting lysosomal accessory protein 2; AltName: Full=ATPase H(+)-transporting lysosomal-interacting protein 2; AltName: Full=ER-localized type I transmembrane adaptor; AltName: Full=Embryonic liver differentiation factor 10; AltName: Full=N14F; AltName: Full=Renin/prorenin receptor; AltName: Full=Vacuolar ATP synthase membrane sector-associated protein M8-9; Short=ATP6M8-9; Short=V-ATPase M8.9 subunit; Flags: Precursor;+++[A0A1B0GTB0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489622}; Flags: Fragment;+++[A0A1B0GTD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489653};+++[A0A1B0GTU8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489845};+++[A0A1B0GU12_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489920};+++[A0A1B0GUT7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490239};+++[A0A1B0GUV3_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490257}; Flags: Fragment;+++[A0A1B0GV24_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490345};+++[A0A1B0GV60_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490382};+++[A0A1B0GVB9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490452};+++[A0A1B0GVC7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490462};+++[A0A1B0GVI9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490532};+++[A0A1B0GVW0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490675};+++[A0A1B0GVZ1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490706};+++[A0A1B0GW13_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490733};+++[A0A1B0GWD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490884}; Flags: Fragment;+++[A0A1B0GWJ8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490954};+++[A0A1C7CYW4_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000367697};+++[B7Z1I9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59846, highly similar to Renin receptor {ECO:0000313|EMBL:BAH11525.1};+++[B7Z413_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52527, highly similar to Renin receptor {ECO:0000313|EMBL:BAH12399.1};+++[H7C240_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000403969}; Flags: Fragment;+++[H7C3E1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000411317};"]
[1016,"'CDH18'",2,1,2,1.66666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0005913///cell-cell adherens junction+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex","GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0045294///alpha-catenin binding+++GO:0070097///delta-catenin binding+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0008013///beta-catenin binding","GO:0007155///cell adhesion+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0098609///cell-cell adhesion+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0044331///cell-cell adhesion mediated by cadherin","cadherin 18","[CAD18_HUMAN|Reviewed]RecName: Full=Cadherin-18; AltName: Full=Cadherin-14; Flags: Precursor;+++[D6RER2_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000424931};+++[D6RIH8_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000425854};+++[H0YAK3_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000427383}; Flags: Fragment;"]
[10160,"'FARP1'",1455,1388,1196,1346.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0048365///Rac GTPase binding","GO:0007275///multicellular organism development+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:0010923///negative regulation of phosphatase activity+++GO:1905606///regulation of presynapse assembly+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048813///dendrite morphogenesis+++GO:0007416///synapse assembly+++GO:0098974///postsynaptic actin cytoskeleton organization","FERM, ARH/RhoGEF and pleckstrin domain protein 1","[FARP1_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1; AltName: Full=Chondrocyte-derived ezrin-like protein; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 1; AltName: Full=Pleckstrin homology domain-containing family C member 2; Short=PH domain-containing family C member 2;+++[A0A1B0GV68_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000490391};+++[A0A2X0TVY0_HUMAN|Unreviewed]SubName: Full=FARP1 {ECO:0000313|EMBL:SPT35756.1}; SubName: Full=FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived) {ECO:0000313|EMBL:EAX08982.1}; Flags: Fragment;+++[C9JME2_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000471242};+++[H0Y783_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410930}; Flags: Fragment;+++[M0QXT1_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469365}; Flags: Fragment;+++[M0QYB0_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469712}; Flags: Fragment;+++[M0R262_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472346}; Flags: Fragment;"]
[10161,"'LPAR6'",1,1,0,0.666666666666667,"04151///PI3K-Akt signaling pathway+++04072///Phospholipase D signaling pathway+++05200///Pathways in cancer+++04080///Neuroactive ligand-receptor interaction","H00667///Woolly hair+++H00784///Localized autosomal recessive hypotrichosis",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0001835///blastocyst hatching+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction","lysophosphatidic acid receptor 6","[LPAR6_HUMAN|Reviewed]RecName: Full=Lysophosphatidic acid receptor 6; Short=LPA receptor 6; Short=LPA-6; AltName: Full=Oleoyl-L-alpha-lysophosphatidic acid receptor; AltName: Full=P2Y purinoceptor 5; Short=P2Y5; AltName: Full=Purinergic receptor 5; AltName: Full=RB intron encoded G-protein coupled receptor;+++[A0A024RDT2_HUMAN|Unreviewed]SubName: Full=HCG30749, isoform CRA_a {ECO:0000313|EMBL:EAX08797.1};+++[B3KVQ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41064 fis, clone TRACH2001021, highly similar to P2Y PURINOCEPTOR 5 {ECO:0000313|EMBL:BAG53867.1};"]
[10162,"'LPCAT3'",707,775,881,787.666666666667,"00564///Glycerophospholipid metabolism+++04216///Ferroptosis",null,null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase   Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:0006629///lipid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling","lysophosphatidylcholine acyltransferase 3","[MBOA5_HUMAN|Reviewed]RecName: Full=Lysophospholipid acyltransferase 5; Short=LPLAT 5; EC=2.3.1.-; AltName: Full=1-acylglycerophosphocholine O-acyltransferase; EC=2.3.1.23; AltName: Full=1-acylglycerophosphoserine O-acyltransferase; EC=2.3.1.n6; AltName: Full=Lysophosphatidylcholine acyltransferase; Short=LPCAT; Short=Lyso-PC acyltransferase; AltName: Full=Lysophosphatidylcholine acyltransferase 3; Short=Lyso-PC acyltransferase 3; AltName: Full=Lysophosphatidylserine acyltransferase; Short=LPSAT; Short=Lyso-PS acyltransferase; AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 5; Short=O-acyltransferase domain-containing protein 5;+++[B7Z3N5_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000443166}; SubName: Full=cDNA FLJ59910, highly similar to Membrane bound O-acyltransferase domain-containing protein 5 {ECO:0000313|EMBL:BAH12271.1};+++[F5GYT3_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000440550};+++[F5H0M4_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000438765};+++[F5H680_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000437827};+++[F5H7K7_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000442454};"]
[10163,"'WASF2'",2468,2187,2387,2347.33333333333,"05132///Salmonella infection+++05231///Choline metabolism in cancer+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005911///cell-cell junction+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0031209///SCAR complex+++GO:0001726///ruffle+++GO:0005769///early endosome","GO:0045296///cadherin binding+++GO:0003779///actin binding+++GO:0017124///SH3 domain binding+++GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0035855///megakaryocyte development+++GO:0030032///lamellipodium assembly+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0001667///ameboidal-type cell migration+++GO:0030048///actin filament-based movement+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0001525///angiogenesis+++GO:0051497///negative regulation of stress fiber assembly+++GO:0006897///endocytosis+++GO:0016601///Rac protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0072673///lamellipodium morphogenesis+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0016032///viral process","WAS protein family member 2","[WASF2_HUMAN|Reviewed]RecName: Full=Wiskott-Aldrich syndrome protein family member 2; Short=WASP family protein member 2; AltName: Full=Protein WAVE-2; AltName: Full=Verprolin homology domain-containing protein 2;+++[Q05BU7_HUMAN|Unreviewed]SubName: Full=WASF2 protein {ECO:0000313|EMBL:AAH32724.1}; Flags: Fragment;"]
[10164,"'CHST4'",1,0,3,1.33333333333333,"00533///Glycosaminoglycan biosynthesis - keratan sulfate",{"$nulls":3},"GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0031228///intrinsic component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0016740///transferase activity","GO:0006955///immune response+++GO:0006790///sulfur compound metabolic process+++GO:0007267///cell-cell signaling+++GO:0006954///inflammatory response+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006477///protein sulfation+++GO:0016266///O-glycan processing+++GO:0007155///cell adhesion+++GO:0005975///carbohydrate metabolic process","carbohydrate sulfotransferase 4","[CHST4_HUMAN|Reviewed]RecName: Full=Carbohydrate sulfotransferase 4; EC=2.8.2.-; AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; Short=GST-3; AltName: Full=High endothelial cells N-acetylglucosamine 6-O-sulfotransferase; Short=HEC-GlcNAc6ST; AltName: Full=L-selectin ligand sulfotransferase; Short=LSST; AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 2; Short=GlcNAc6ST-2; Short=Gn6st-2;"]
[10165,"'SLC25A13'",578,459,688,575,null,"H01305///Global cerebral hypomyelination+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00185///Citrullinemia (CTLN)",null,null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion","GO:0015183///L-aspartate transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0005313///L-glutamate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015172///acidic amino acid transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0005215///transporter activity+++GO:0046872///metal ion binding","GO:0006839///mitochondrial transport+++GO:0015810///aspartate transmembrane transport+++GO:0055085///transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0015813///L-glutamate transmembrane transport+++GO:0045333///cellular respiration+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0043490///malate-aspartate shuttle+++GO:0051592///response to calcium ion+++GO:0070778///L-aspartate transmembrane transport+++GO:0006094///gluconeogenesis","solute carrier family 25 member 13","[CMC2_HUMAN|Reviewed]RecName: Full=Calcium-binding mitochondrial carrier protein Aralar2; AltName: Full=Citrin; AltName: Full=Mitochondrial aspartate glutamate carrier 2; AltName: Full=Solute carrier family 25 member 13;+++[Q75KX8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07527.1}; Flags: Fragment;+++[Q75M55_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07513.1}; Flags: Fragment;+++[R4GN64_HUMAN|Unreviewed]SubName: Full=Calcium-binding mitochondrial carrier protein Aralar2 {ECO:0000313|Ensembl:ENSP00000473505};"]
[10166,"'SLC25A15'",87.02,74.02,61.88,74.3066666666667,null,"H01268///Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005664///nuclear origin of replication recognition complex+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0022857///transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0000064///L-ornithine transmembrane transporter activity","GO:0033314///mitotic DNA replication checkpoint+++GO:1990575///mitochondrial L-ornithine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0000050///urea cycle+++GO:0006270///DNA replication initiation+++GO:0000278///mitotic cell cycle+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006260///DNA replication","solute carrier family 25 member 15","[ORNT1_HUMAN|Reviewed]RecName: Full=Mitochondrial ornithine transporter 1; AltName: Full=Solute carrier family 25 member 15;+++[F2Z354_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000431429};+++[Q5VZD9_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000415826}; Flags: Fragment;"]
[10168,"'ZNF197'",189.69,96.59,139.05,141.776666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 197","[ZN197_HUMAN|Reviewed]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[C9JIP4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000390115}; Flags: Fragment;+++[C9JQH5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000394713}; Flags: Fragment;+++[F8WDZ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000402483};+++[F8WEU5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000334616};+++[M0QYR3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000470025};+++[Q4G1C8_HUMAN|Unreviewed]SubName: Full=ZNF197 protein {ECO:0000313|EMBL:AAH17584.1}; Flags: Fragment;+++[Q7Z6G1_HUMAN|Unreviewed]SubName: Full=Znf197 truncated protein {ECO:0000313|EMBL:AAP57399.1}; Flags: Fragment;+++[Q86XA2_HUMAN|Unreviewed]SubName: Full=ZNF20 protein {ECO:0000313|EMBL:AAH45814.1};"]
[10169,"'SERF2'",7640,8582,7244,7822,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008150///biological_process","small EDRK-rich factor 2","[SERF2_HUMAN|Reviewed]RecName: Full=Small EDRK-rich factor 2; AltName: Full=Gastric cancer-related protein VRG107; AltName: Full=Protein 4F5-related; Short=4F5rel; Short=h4F5rel;+++[B8ZZY7_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386316};+++[B9A031_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000387041};+++[C9JQZ0_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000394660}; Flags: Fragment;+++[F8WBN3_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386290};+++[F8WBV6_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000391027};"]
[1017,"'CDK2'",190,191,186,189,"04934///Cushing's syndrome+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++04914///Progesterone-mediated oocyte maturation+++05226///Gastric cancer+++05215///Prostate cancer+++04151///PI3K-Akt signaling pathway+++04114///Oocyte meiosis+++05200///Pathways in cancer+++05162///Measles+++04218///Cellular senescence+++05203///Viral carcinogenesis+++04110///Cell cycle+++05168///Herpes simplex infection+++04068///FoxO signaling pathway+++05161///Hepatitis B+++05222///Small cell lung cancer+++05169///Epstein-Barr virus infection",null,"M00692///Cell cycle - G1/S transition+++M00693///Cell cycle - G2/M transition",null,"GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0097123///cyclin A1-CDK2 complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0000805///X chromosome+++GO:0097134///cyclin E1-CDK2 complex+++GO:0000781///chromosome, telomeric region+++GO:0097124///cyclin A2-CDK2 complex+++GO:0097135///cyclin E2-CDK2 complex+++GO:0000806///Y chromosome+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000793///condensed chromosome+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0015030///Cajal body+++GO:0005856///cytoskeleton","GO:0097472///cyclin-dependent protein kinase activity+++GO:0035173///histone kinase activity+++GO:0000287///magnesium ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0000166///nucleotide binding+++GO:0019904///protein domain specific binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0046872///metal ion binding","GO:0051301///cell division+++GO:0016310///phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006260///DNA replication+++GO:0006468///protein phosphorylation+++GO:0006813///potassium ion transport+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0018105///peptidyl-serine phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006281///DNA repair+++GO:0008284///positive regulation of cell proliferation+++GO:0032298///positive regulation of DNA-dependent DNA replication initiation+++GO:0051726///regulation of cell cycle+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0007099///centriole replication+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051298///centrosome duplication+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060968///regulation of gene silencing+++GO:0007049///cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016572///histone phosphorylation","cyclin dependent kinase 2","[CDK2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2; EC=2.7.11.22 {ECO:0000269|PubMed:1396589, ECO:0000269|PubMed:28666995, ECO:0000269|PubMed:9030781}; AltName: Full=Cell division protein kinase 2; AltName: Full=p33 protein kinase;+++[A0A024RB10_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW96857.1};+++[A0A024RB77_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_b {ECO:0000313|EMBL:EAW96860.1};+++[B4DDL9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54979, highly similar to Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG56780.1};+++[E7ESI2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000393605};+++[G3V317_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000450983};+++[G3V5T9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000452514}; SubName: Full=Cyclin-dependent kinase 2, isoform CRA_c {ECO:0000313|EMBL:EAW96859.1};"]
[10170,"'DHRS9'",1,1,3,1.66666666666667,"01100///Metabolic pathways+++00830///Retinol metabolism",null,null,"R02124///retinol:NAD+ oxidoreductase   Retinol + NAD+ <=> Retinal + NADH + H+","GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0016854///racemase and epimerase activity+++GO:0016491///oxidoreductase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0004022///alcohol dehydrogenase (NAD) activity","GO:0042572///retinol metabolic process+++GO:0030855///epithelial cell differentiation+++GO:0055114///oxidation-reduction process+++GO:0002138///retinoic acid biosynthetic process+++GO:0008209///androgen metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0042448///progesterone metabolic process","dehydrogenase/reductase 9","[DHRS9_HUMAN|Reviewed]RecName: Full=Dehydrogenase/reductase SDR family member 9; EC=1.1.-.-; AltName: Full=3-alpha hydroxysteroid dehydrogenase; Short=3-alpha-HSD; AltName: Full=NADP-dependent retinol dehydrogenase/reductase; AltName: Full=RDH-E2; AltName: Full=RDHL; AltName: Full=Retinol dehydrogenase 15; AltName: Full=Short chain dehydrogenase/reductase family 9C member 4; AltName: Full=Short-chain dehydrogenase/reductase retSDR8; AltName: Full=Tracheobronchial epithelial cell-specific retinol dehydrogenase; Short=RDH-TBE; Flags: Precursor;+++[C9J430_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 9 {ECO:0000313|Ensembl:ENSP00000391214}; Flags: Fragment;+++[Q4ZG83_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RDHL {ECO:0000313|EMBL:AAX88964.1}; Flags: Fragment;+++[Q53TL1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RDHL {ECO:0000313|EMBL:AAY24306.1}; Flags: Fragment;"]
[10171,"'RCL1'",153,120,114,129,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003824///catalytic activity+++GO:0004521///endoribonuclease activity","GO:0042254///ribosome biogenesis+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006396///RNA processing+++GO:0006364///rRNA processing+++GO:0008150///biological_process+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","RNA terminal phosphate cyclase like 1","[RCL1_HUMAN|Reviewed]RecName: Full=RNA 3'-terminal phosphate cyclase-like protein;+++[Q5VYW8_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000371151};+++[Q5VZU2_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000413381}; Flags: Fragment;+++[Q5VZU3_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000412000};"]
[10172,"'ZNF256'",50,32,36,39.3333333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 256","[ZN256_HUMAN|Reviewed]RecName: Full=Zinc finger protein 256; AltName: Full=Bone marrow zinc finger 3; Short=BMZF-3;+++[L8E7T8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF256 {ECO:0000313|EMBL:CCQ43335.1};+++[M0R2X0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 256 {ECO:0000313|Ensembl:ENSP00000472858};"]
[10174,"'SORBS3'",2784,3217,3149,3050,"04022///cGMP-PKG signaling pathway+++04662///B cell receptor signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04728///Dopaminergic synapse+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++04720///Long-term potentiation+++05014///Amyotrophic lateral sclerosis (ALS)+++04724///Glutamatergic synapse+++04380///Osteoclast differentiation+++04218///Cellular senescence+++05010///Alzheimer's disease+++04137///Mitophagy - animal+++04658///Th1 and Th2 cell differentiation+++04660///T cell receptor signaling pathway+++04659///Th17 cell differentiation+++04360///Axon guidance+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04370///VEGF signaling pathway+++04010///MAPK signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05031///Amphetamine addiction+++04310///Wnt signaling pathway+++04020///Calcium signaling pathway+++04625///C-type lectin receptor signaling pathway+++05166///HTLV-I infection+++04921///Oxytocin signaling pathway","H02150///Infantile or early childhood epileptic encephalopathy",null,null,"GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005856///cytoskeleton","GO:0017166///vinculin binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0008134///transcription factor binding","GO:0051495///positive regulation of cytoskeleton organization+++GO:0006936///muscle contraction+++GO:0043410///positive regulation of MAPK cascade+++GO:0051496///positive regulation of stress fiber assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0031589///cell-substrate adhesion+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion","sorbin and SH3 domain containing 3","[VINEX_HUMAN|Reviewed]RecName: Full=Vinexin; AltName: Full=SH3-containing adapter molecule 1; Short=SCAM-1; AltName: Full=Sorbin and SH3 domain-containing protein 3;+++[E5RIA0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429479}; Flags: Fragment;+++[E5RJP2_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000431128}; Flags: Fragment;+++[E7EQH0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429723};+++[H0YAU6_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428102}; Flags: Fragment;+++[H0YAZ3_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428327}; Flags: Fragment;+++[H0YB51_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428678}; Flags: Fragment;+++[Q9BT70_HUMAN|Unreviewed]SubName: Full=SORBS3 protein {ECO:0000313|EMBL:AAH04314.1}; Flags: Fragment;"]
[10175,"'CNIH1'",533,453,539,508.333333333333,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0012507///ER to Golgi transport vesicle membrane",null,"GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","cornichon family AMPA receptor auxiliary protein 1","[CNIH1_HUMAN|Reviewed]RecName: Full=Protein cornichon homolog 1; Short=CNIH-1; AltName: Full=Cornichon family AMPA receptor auxiliary protein 1; AltName: Full=Protein cornichon homolog; AltName: Full=T-cell growth-associated molecule 77; Short=TGAM77;+++[A8MVW4_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW80636.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000378940};+++[B2R4P1_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW80635.1}; SubName: Full=cDNA FLJ90300 fis, clone NT2RP2000533, highly similar to Cornichon homolog {ECO:0000313|EMBL:BAG52000.1}; SubName: Full=cDNA, FLJ92163, Homo sapiens cornichon homolog (Drosophila) (CNIH), mRNA {ECO:0000313|EMBL:BAG34838.1};+++[G3V3B2_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451142};+++[G3V474_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451640};+++[G3V4K0_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAW80637.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451852};+++[G3V5P8_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452457};+++[G3V5Q6_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452466};"]
[10178,"'TENM1'",8,5,2,5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0043005///neuron projection+++GO:0016363///nuclear matrix+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0008201///heparin binding+++GO:0042803///protein homodimerization activity+++GO:0050839///cell adhesion molecule binding","GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0006955///immune response+++GO:0007218///neuropeptide signaling pathway+++GO:0090316///positive regulation of intracellular protein transport+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007165///signal transduction+++GO:0043406///positive regulation of MAP kinase activity+++GO:0008285///negative regulation of cell proliferation+++GO:0051491///positive regulation of filopodium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0048666///neuron development+++GO:0007399///nervous system development","teneurin transmembrane protein 1","[TEN1_HUMAN|Reviewed]RecName: Full=Teneurin-1; Short=Ten-1; AltName: Full=Protein Odd Oz/ten-m homolog 1; AltName: Full=Tenascin-M1; Short=Ten-m1; AltName: Full=Teneurin transmembrane protein 1; Contains: RecName: Full=Ten-1 intracellular domain; Short=IDten-1; Short=Ten-1 ICD; Contains: RecName: Full=Teneurin C-terminal-associated peptide; Short=TCPA-1; AltName: Full=Ten-1 extracellular domain; Short=Ten-1 ECD;+++[B7ZMH4_HUMAN|Unreviewed]SubName: Full=ODZ1 protein {ECO:0000313|EMBL:AAI44544.1};+++[G3CAS6_HUMAN|Unreviewed]SubName: Full=Odz, odd Oz/ten-m homolog 1 (Drosophila) {ECO:0000313|EMBL:CCD17865.1}; Flags: Fragment;+++[L8EAN5_HUMAN|Unreviewed]SubName: Full=Alternative protein ODZ1 {ECO:0000313|EMBL:CCQ43428.1};"]
[10179,"'RBM7'",311,236.01,203,250.003333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding","GO:0051321///meiotic cell cycle+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 7","[RBM7_HUMAN|Reviewed]RecName: Full=RNA-binding protein 7; AltName: Full=RNA-binding motif protein 7;+++[F5GXV8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440949};+++[F5GY08_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440923};+++[F5H606_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437998};+++[F5H674_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437847};+++[G3V1T9_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_a {ECO:0000313|EMBL:EAW67246.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000445848};+++[J3KPD3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_c {ECO:0000313|EMBL:EAW67248.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000364639};+++[Q6IRX3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7 {ECO:0000313|EMBL:AAH70262.1};"]
[1018,"'CDK3'",44,44,48,45.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0045023///G0 to G1 transition+++GO:0007049///cell cycle+++GO:0006468///protein phosphorylation+++GO:0008283///cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051301///cell division+++GO:0016310///phosphorylation","cyclin dependent kinase 3","[CDK3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 3; EC=2.7.11.22; AltName: Full=Cell division protein kinase 3;+++[A0A024R8R3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3, isoform CRA_a {ECO:0000313|EMBL:EAW89354.1};+++[K7EJ83_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000465062}; Flags: Fragment;+++[K7ELV5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000466237}; Flags: Fragment;"]
[10180,"'RBM6'",854,733,777,788,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006396///RNA processing","RNA binding motif protein 6","[RBM6_HUMAN|Reviewed]RecName: Full=RNA-binding protein 6; AltName: Full=Lung cancer antigen NY-LU-12; AltName: Full=Protein G16; AltName: Full=RNA-binding motif protein 6; AltName: Full=RNA-binding protein DEF-3;+++[A8K6Q4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76888, highly similar to Homo sapiens RNA binding motif protein 6 (RBM6), mRNA {ECO:0000313|EMBL:BAF84408.1};+++[C9J250_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000392475};+++[C9JII0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000403865}; Flags: Fragment;+++[C9JMC8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000389763}; Flags: Fragment;+++[C9JSL1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000394336}; Flags: Fragment;+++[E9PGM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396466};+++[F8WCA5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000406548};+++[F8WCT0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396410};+++[F8WF63_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000399942};"]
[10181,"'RBM5'",1514,1323,1449,1428.66666666667,null,"H00943///TARP syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0008380///RNA splicing+++GO:0008285///negative regulation of cell proliferation+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006915///apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000245///spliceosomal complex assembly+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process","RNA binding motif protein 5","[RBM5_HUMAN|Reviewed]RecName: Full=RNA-binding protein 5; AltName: Full=Protein G15; AltName: Full=Putative tumor suppressor LUCA15; AltName: Full=RNA-binding motif protein 5; AltName: Full=Renal carcinoma antigen NY-REN-9;+++[A0A024R2U6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW65042.1};+++[A0A0S2Z549_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 1 {ECO:0000313|EMBL:ALQ33963.1}; Flags: Fragment;+++[A0A0S2Z5U0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 2 {ECO:0000313|EMBL:ALQ33964.1};+++[C9J9P7_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000406119}; Flags: Fragment;+++[C9JFQ5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000390711}; Flags: Fragment;+++[C9JR02_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000394622}; Flags: Fragment;+++[E1CJT4_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 variant {ECO:0000313|EMBL:BAJ19019.1};+++[F8W910_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000384872}; Flags: Fragment;+++[F8WE23_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000414218};+++[H7BYM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000378603}; Flags: Fragment;"]
[10184,"'LHFPL2'",1087,871,989,982.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0031092///platelet alpha granule membrane+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0007338///single fertilization+++GO:1905516///positive regulation of fertilization+++GO:0002576///platelet degranulation+++GO:0046545///development of primary female sexual characteristics+++GO:0008150///biological_process+++GO:0046546///development of primary male sexual characteristics","LHFPL tetraspan subfamily member 2","[LHPL2_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 2 protein {ECO:0000312|HGNC:HGNC:6588}; AltName: Full=Lipoma HMGIC fusion partner-like 2 protein {ECO:0000312|HGNC:HGNC:6588};+++[A0A024RAM8_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW95819.1};"]
[10186,"'LHFPL6'",2791,2611,3527,2976.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","LHFPL tetraspan subfamily member 6","[LHPL6_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 6 protein {ECO:0000312|HGNC:HGNC:6586}; AltName: Full=Lipoma HMGIC fusion partner {ECO:0000312|HGNC:HGNC:6586}; Flags: Precursor;+++[A0A024RDR1_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner, isoform CRA_a {ECO:0000313|EMBL:EAX08617.1};"]
[10188,"'TNK2'",778,816,689,761,{"$nulls":4},"GO:0005912///adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0097268///cytoophidium+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0070436///Grb2-EGFR complex+++GO:0005634///nucleus+++GO:0030136///clathrin-coated vesicle+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005905///clathrin-coated pit","GO:0016740///transferase activity+++GO:0005095///GTPase inhibitor activity+++GO:0042802///identical protein binding+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0050699///WW domain binding+++GO:0046872///metal ion binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0007264///small GTPase mediated signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0034260///negative regulation of GTPase activity+++GO:0030154///cell differentiation+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation","tyrosine kinase non receptor 2","[ACK1_HUMAN|Reviewed]RecName: Full=Activated CDC42 kinase 1; Short=ACK-1; EC=2.7.10.2 {ECO:0000269|PubMed:10652228, ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:16472662, ECO:0000269|PubMed:18993068, ECO:0000269|PubMed:20333297}; EC=2.7.11.1 {ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:18993068}; AltName: Full=Tyrosine kinase non-receptor protein 2;+++[B3KXJ4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45547 fis, clone BRTHA2035743, highly similar to Activated CDC42 kinase 1 {ECO:0000313|EMBL:BAG54506.1};+++[C9J1X3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392546};+++[C9JDG3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000395154}; Flags: Fragment;+++[C9JIR5_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390088}; Flags: Fragment;+++[F8WER3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000393707};+++[H0Y5H7_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000398614}; Flags: Fragment;+++[H7BZM8_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390435}; Flags: Fragment;+++[H7BZZ3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392253}; Flags: Fragment;+++[H7C343_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000409462}; Flags: Fragment;+++[H7C412_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000415126}; Flags: Fragment;"]
[10189,"'ALYREF'",800,795,729,774.666666666667,"03013///RNA transport+++03040///Spliceosome+++05168///Herpes simplex infection+++03015///mRNA surveillance pathway",null,"M00406///TREX complex+++M00430///Exon junction complex (EJC)",null,"GO:0005681///spliceosomal complex+++GO:0070062///extracellular exosome+++GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0000784///nuclear chromosome, telomeric region+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0031124///mRNA 3'-end processing+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0001649///osteoblast differentiation+++GO:0051028///mRNA transport+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0016032///viral process+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000018///regulation of DNA recombination+++GO:0031297///replication fork processing","Aly/REF export factor","[THOC4_HUMAN|Reviewed]RecName: Full=THO complex subunit 4; Short=Tho4; AltName: Full=Ally of AML-1 and LEF-1; AltName: Full=Aly/REF export factor; AltName: Full=Transcriptional coactivator Aly/REF; AltName: Full=bZIP-enhancing factor BEF;+++[E9PB61_HUMAN|Unreviewed]SubName: Full=THO complex subunit 4 {ECO:0000313|Ensembl:ENSP00000421592};"]
[1019,"'CDK4'",1412,1438,1488,1446,"05200///Pathways in cancer+++05162///Measles+++05223///Non-small cell lung cancer+++04115///p53 signaling pathway+++05166///HTLV-I infection+++05224///Breast cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05222///Small cell lung cancer+++05165///Human papillomavirus infection+++04110///Cell cycle+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++05219///Bladder cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05161///Hepatitis B+++04218///Cellular senescence+++05212///Pancreatic cancer+++05218///Melanoma+++05225///Hepatocellular carcinoma+++01522///Endocrine resistance+++05163///Human cytomegalovirus infection+++05220///Chronic myeloid leukemia+++05214///Glioma+++04660///T cell receptor signaling pathway+++04530///Tight junction+++04934///Cushing's syndrome","H00042///Glioma+++H00030///Cervical cancer+++H00038///Melanoma","M00692///Cell cycle - G1/S transition",null,"GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005730///nucleolus+++GO:0097129///cyclin D2-CDK4 complex+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000785///chromatin+++GO:0005923///bicellular tight junction+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005667///transcription factor complex","GO:0030332///cyclin binding+++GO:0016740///transferase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0044877///protein-containing complex binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0071157///negative regulation of cell cycle arrest+++GO:0046890///regulation of lipid biosynthetic process+++GO:0033574///response to testosterone+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0032869///cellular response to insulin stimulus+++GO:0071353///cellular response to interleukin-4+++GO:0050994///regulation of lipid catabolic process+++GO:0060612///adipose tissue development+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:0010033///response to organic substance+++GO:0043065///positive regulation of apoptotic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0002088///lens development in camera-type eye+++GO:0016310///phosphorylation+++GO:0010468///regulation of gene expression+++GO:0006468///protein phosphorylation+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007623///circadian rhythm+++GO:0055093///response to hyperoxia+++GO:0045727///positive regulation of translation+++GO:0045793///positive regulation of cell size+++GO:0051301///cell division+++GO:0007165///signal transduction+++GO:0040014///regulation of multicellular organism growth+++GO:0031100///animal organ regeneration+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:1904637///cellular response to ionomycin+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010288///response to lead ion+++GO:0009636///response to toxic substance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity","cyclin dependent kinase 4","[CDK4_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4; EC=2.7.11.22; AltName: Full=Cell division protein kinase 4; AltName: Full=PSK-J3;+++[A0A024RBB6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4, isoform CRA_a {ECO:0000313|EMBL:EAW97060.1};+++[F8VTV8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448098};+++[F8VWX7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449179}; Flags: Fragment;+++[F8VXD2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449391}; Flags: Fragment;+++[F8VYH9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448963}; Flags: Fragment;+++[F8VYY1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448885};+++[F8VZ13_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447005};+++[F8VZ51_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447779}; Flags: Fragment;+++[F8VZZ0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447274}; Flags: Fragment;+++[F8W1L8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000446763}; Flags: Fragment;+++[Q6LC83_HUMAN|Unreviewed]SubName: Full=Cyclin dependent protein kinase {ECO:0000313|EMBL:AAB50213.1}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_b {ECO:0000313|EMBL:EAW97059.1};+++[Q96BE9_HUMAN|Unreviewed]SubName: Full=CDK4 protein {ECO:0000313|EMBL:AAH15669.1}; SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000316889}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_c {ECO:0000313|EMBL:EAW97061.1};"]
[10190,"'TXNDC9'",276,227,192,231.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0008150///biological_process+++GO:0045454///cell redox homeostasis","thioredoxin domain containing 9","[TXND9_HUMAN|Reviewed]RecName: Full=Thioredoxin domain-containing protein 9; AltName: Full=ATP-binding protein associated with cell differentiation; AltName: Full=Protein 1-4;+++[B8ZZX4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000386889}; Flags: Fragment;+++[F8WBV5_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000391046};+++[F8WCJ3_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000406388};+++[G3XAJ4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain containing 9, isoform CRA_a {ECO:0000313|EMBL:EAX01868.1}; SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000402827};"]
[101927245,"'LOC101927245'",8,6,9,7.66666666666667,{"$nulls":7},"vegetative cell wall protein gp1-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927262,"'LOC101927262'",0,0,3,1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0030971///receptor tyrosine kinase binding+++GO:0030298///receptor signaling protein tyrosine kinase activator activity","GO:0070378///positive regulation of ERK5 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0010976///positive regulation of neuron projection development","melanoma-associated antigen C1-like","[ALKL1_HUMAN|diamond]RecName: Full=ALK and LTK ligand 1 {ECO:0000312|HGNC:HGNC:33775}; AltName: Full=Augmentor beta {ECO:0000303|PubMed:26630010}; Short=AUG-beta {ECO:0000303|PubMed:26630010}; AltName: Full=Protein FAM150A; Flags: Precursor;+++[ALKL1_MOUSE|diamond]RecName: Full=ALK and LTK ligand 1; AltName: Full=Augmentor beta; AltName: Full=Protein FAM150A; Flags: Precursor;+++[ALKL2_HUMAN|diamond]RecName: Full=ALK and LTK ligand 2 {ECO:0000312|HGNC:HGNC:27683}; AltName: Full=Augmentor alpha {ECO:0000303|PubMed:26630010}; Short=AUG-alpha {ECO:0000303|PubMed:26630010}; AltName: Full=Protein FAM150B; Flags: Precursor;+++[ALKL2_MOUSE|diamond]RecName: Full=ALK and LTK ligand 2; AltName: Full=Protein FAM150B; Flags: Precursor;+++[ALKL2_RAT|diamond]RecName: Full=ALK and LTK ligand 2; AltName: Full=Protein FAM150B; Flags: Precursor;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[MST2_DROHY|diamond]RecName: Full=Axoneme-associated protein mst101(2);+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927322,"'LOC101927322'",2,3,4,3,"04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++05152///Tuberculosis+++04064///NF-kappa B signaling pathway+++04662///B cell receptor signaling pathway",{"$nulls":3},"GO:0005730///nucleolus+++GO:0001650///fibrillar center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0032449///CBM complex+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0002020///protease binding+++GO:0043621///protein self-association+++GO:0042802///identical protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008233///peptidase activity","GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002726///positive regulation of T cell cytokine production+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006508///proteolysis+++GO:0050852///T cell receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:2000321///positive regulation of T-helper 17 cell differentiation+++GO:0051259///protein complex oligomerization+++GO:0001923///B-1 B cell differentiation+++GO:0009620///response to fungus+++GO:0002237///response to molecule of bacterial origin+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051168///nuclear export+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0042098///T cell proliferation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0006952///defense response+++GO:0032743///positive regulation of interleukin-2 production","uncharacterized LOC101927322","[MALT1_HUMAN|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1; EC=3.4.22.-; AltName: Full=MALT lymphoma-associated translocation; AltName: Full=Paracaspase;+++[MALT1_MOUSE|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; EC=3.4.22.-; AltName: Full=Paracaspase;"]
[101927345,"'LOC101927345'",57.75,45.49,33.53,45.59,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"putative ankyrin repeat domain-containing protein 20A12 pseudogene","[A2012_HUMAN|diamond]RecName: Full=Putative ankyrin repeat domain-containing protein 20A12 pseudogene {ECO:0000305};+++[AN18A_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18A;+++[AN18B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18B;+++[ANR26_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000305};+++[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[SNX18_MOUSE|diamond]RecName: Full=Sorting nexin-18; AltName: Full=Sorting nexin-associated Golgi protein 1;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927401,"'LOC101927401'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016604///nuclear body+++GO:0005886///plasma membrane+++GO:0030018///Z disc+++GO:0005829///cytosol+++GO:0031430///M band+++GO:0030016///myofibril+++GO:0042383///sarcolemma","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0008307///structural constituent of muscle+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005524///ATP binding+++GO:0031432///titin binding+++GO:0005516///calmodulin binding+++GO:0030506///ankyrin binding+++GO:0004674///protein serine/threonine kinase activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0036309///protein localization to M-band+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0045214///sarcomere organization+++GO:0035023///regulation of Rho protein signal transduction","MAGE-like protein 2","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[OBSCN_HUMAN|diamond]RecName: Full=Obscurin; EC=2.7.11.1 {ECO:0000250|UniProtKB:A2AAJ9}; AltName: Full=Obscurin-RhoGEF; AltName: Full=Obscurin-myosin light chain kinase; Short=Obscurin-MLCK;+++[OBSCN_MOUSE|diamond]RecName: Full=Obscurin; EC=2.7.11.1 {ECO:0000269|PubMed:23392350}; AltName: Full=Obscurin-RhoGEF; AltName: Full=Obscurin-myosin light chain kinase; Short=Obscurin-MLCK;+++[SPEG_DANRE|diamond]RecName: Full=Striated muscle preferentially expressed protein kinase; EC=2.7.11.1;+++[SPEG_MOUSE|diamond]RecName: Full=Striated muscle-specific serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[SPEG_RAT|diamond]RecName: Full=Striated muscle-specific serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927423,"'PANO1'",30,32,21,27.6666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus",null,"GO:0031647///regulation of protein stability+++GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process","proapoptotic nucleolar protein 1","[PANO1_HUMAN|Reviewed]RecName: Full=Proapoptotic nucleolar protein 1 {ECO:0000303|PubMed:22094112, ECO:0000312|HGNC:HGNC:51237};"]
[101927506,"'LOC101927506'",110.68,81.68,115.56,102.64,"01100///Metabolic pathways+++04137///Mitophagy - animal+++00380///Tryptophan metabolism+++04140///Autophagy - animal",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin+++R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0005525///GTP binding","GO:0006310///DNA recombination+++GO:0007049///cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division+++GO:0032199///reverse transcription involved in RNA-mediated transposition","uncharacterized LOC101927506","[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NP10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Np9 protein; AltName: Full=HERV-K10 Np9 protein; AltName: Full=HERV-K107 Np9 protein; AltName: Full=HERV-K_5q33.3 provirus Np9 protein;+++[NP24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Np9 protein; AltName: Full=HERV-K101 Np9 protein; AltName: Full=HERV-K_22q11.21 provirus Np9 protein;+++[NP5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Np9 protein; AltName: Full=Endogenous retrovirus K protein 5; AltName: Full=HERV-K(II) Np9 protein; AltName: Full=HERV-K_3q12.3 provirus Np9 protein;+++[NP7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Np9 protein; AltName: Full=HERV-K(III) Np9 protein; AltName: Full=HERV-K102 Np9 protein; AltName: Full=HERV-K_1q22 provirus Np9 protein;+++[PRORY_HUMAN|diamond]RecName: Full=Proline-rich protein, Y-linked;+++[RL23A_BOVIN|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_HUMAN|diamond]RecName: Full=60S ribosomal protein L23a; AltName: Full=Large ribosomal subunit protein uL23 {ECO:0000303|PubMed:24524803};+++[RL23A_MOUSE|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_RAT|diamond]RecName: Full=60S ribosomal protein L23a;+++[SEP14_BOVIN|diamond]RecName: Full=Septin-14;+++[SEP14_HUMAN|diamond]RecName: Full=Septin-14;+++[SEP14_MOUSE|diamond]RecName: Full=Septin-14;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927509,"'LOC101927509'",23,32,21,25.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","basic proline-rich protein-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927601,"'GOLGA6L19'",0,0,8.52,2.84,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"golgin A6 family-like 19","[GG6LS_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 19;"]
[101927655,"'ZASP'",1.56,0,0,0.52,{"$nulls":7},"ZO-2 associated speckle protein","[E3Q1N2_HUMAN|Unreviewed]SubName: Full=ZO-2 associated speckle protein {ECO:0000313|EMBL:CBX53310.1};"]
[101927789,"'LOC101927789'",21,22,20,21,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated","putative ubiquitin-like protein FUBI-like protein ENSP00000310146","[GT2D2_BOVIN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GT2D2_MOUSE|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GTD2A_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2A; Short=GTF2I repeat domain-containing protein 2A; AltName: Full=Transcription factor GTF2IRD2-alpha;+++[GTD2B_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2B; Short=GTF2I repeat domain-containing protein 2B; AltName: Full=Transcription factor GTF2IRD2-beta;+++[NANGN_HUMAN|diamond]RecName: Full=NANOG neighbor homeobox; AltName: Full=Homeobox protein C14;+++[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[UBIML_HUMAN|diamond]RecName: Full=Putative ubiquitin-like protein FUBI-like protein ENSP00000310146;+++[UBIM_MOUSE|diamond]RecName: Full=Ubiquitin-like protein FUBI; AltName: Full=Monoclonal non-specific suppressor factor beta; Short=MNSF-beta;+++[UBIM_MUSSI|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_PIG|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_RAT|diamond]RecName: Full=Ubiquitin-like protein FUBI;"]
[101927824,"'LOC101927824'",4,2,3,3,{"$nulls":7},"translation initiation factor IF-2-like","[A0A1D5R5M3_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000055611};+++[A0A2K5TP44_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000001824};+++[A0A2K5UCW2_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000010203};+++[I7G9B2_MACFA|diamond]SubName: Full=Macaca fascicularis brain cDNA clone: QtrA-16029, similar to human glycoprotein VI (platelet) (GP6), mRNA, RefSeq: NM_016363.3 {ECO:0000313|EMBL:BAE91381.1};+++[Q95K85_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAB60791.1};"]
[101928095,"'LOC101928095'",4.28,7,8.02,6.43333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0003677///DNA binding+++GO:0004984///olfactory receptor activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0008270///zinc ion binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0015074///DNA integration+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0006310///DNA recombination","serine/arginine-rich splicing factor RSZ22-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[O7E24_HUMAN|diamond]RecName: Full=Olfactory receptor 7E24; AltName: Full=Olfactory receptor OR19-14;+++[OLF18_MOUSE|diamond]RecName: Full=Olfactory receptor 18; AltName: Full=Olfactory receptor 145-1; AltName: Full=Olfactory receptor TPCR34;+++[OR7AA_HUMAN|diamond]RecName: Full=Olfactory receptor 7A10; AltName: Full=OST027; AltName: Full=Olfactory receptor OR19-18;+++[OR7C2_HUMAN|diamond]RecName: Full=Olfactory receptor 7C2; AltName: Full=Olfactory receptor 19-18; Short=OR19-18; AltName: Full=Olfactory receptor 7C3; AltName: Full=Olfactory receptor OR19-22;+++[OR7D4_HUMAN|diamond]RecName: Full=Olfactory receptor 7D4; AltName: Full=OR19-B; AltName: Full=Odorant receptor family subfamily D member 4RT; AltName: Full=Olfactory receptor OR19-7;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101928120,"'LOC101928120'",28,17,26,23.6666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:1990907///beta-catenin-TCF complex","GO:0035034///histone acetyltransferase regulator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0030879///mammary gland development+++GO:0048589///developmental growth+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0001701///in utero embryonic development+++GO:0035563///positive regulation of chromatin binding+++GO:0002088///lens development in camera-type eye+++GO:0001822///kidney development+++GO:0009791///post-embryonic development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060021///roof of mouth development+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0007420///brain development+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0007289///spermatid nucleus differentiation","uncharacterized LOC101928120","[PYGO2_HUMAN|diamond]RecName: Full=Pygopus homolog 2;"]
[101928212,"'LOC101928212'",1,4,3,2.66666666666667,{"$nulls":4},"GO:0030176///integral component of endoplasmic reticulum membrane","GO:0061513///glucose 6-phosphate:inorganic phosphate antiporter activity","GO:0015760///glucose-6-phosphate transport","uncharacterized LOC101928212","[A0A2K6U6V0_SAIBB|diamond]SubName: Full=Solute carrier family 37 member 1 {ECO:0000313|Ensembl:ENSSBOP00000027629};"]
[101928422,"'LOC101928422'",35.78,64.96,38,46.2466666666667,{"$nulls":4},"GO:0030054///cell junction+++GO:0005886///plasma membrane","GO:0044325///ion channel binding","GO:0090314///positive regulation of protein targeting to membrane+++GO:0030335///positive regulation of cell migration+++GO:0010360///negative regulation of anion channel activity","TRPM8 channel-associated factor 2-like","[TCAF1_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF1_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[TCAF1_PONAB|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF2_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF2_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 2 {ECO:0000303|PubMed:25559186};+++[TCAF2_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF3_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000312|MGI:MGI:3042585}; AltName: Full=Experimental autoimmune prostatitis antigen 2;+++[TCAF3_RAT|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000305}; AltName: Full=Experimental autoimmune prostatitis antigen 2 homolog;"]
[101928436,"'LOC101928436'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","uncharacterized LOC101928436","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[101928448,"'C5orf67'",0,3,0,1,{"$nulls":4},"GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome","GO:0048027///mRNA 5'-UTR binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:1902167///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006412///translation+++GO:1904803///regulation of translation involved in cellular response to UV+++GO:0006413///translational initiation+++GO:0042273///ribosomal large subunit biogenesis+++GO:0034644///cellular response to UV+++GO:0002181///cytoplasmic translation+++GO:0071480///cellular response to gamma radiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006364///rRNA processing+++GO:0045727///positive regulation of translation+++GO:1902164///positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","chromosome 5 open reading frame 67","[CE067_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf67;+++[A0A087WXD6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C5orf67 {ECO:0000313|Ensembl:ENSP00000480926};"]
[101928527,"'PIGBOS1'",75,81,91,82.3333333333333,{"$nulls":4},"GO:0005576///extracellular region",null,null,"PIGB opposite strand 1","[PIOS1_HUMAN|Reviewed]RecName: Full=Protein PIGBOS1 {ECO:0000305}; AltName: Full=PIGB opposite strand protein {ECO:0000312|HGNC:HGNC:50696}; Flags: Precursor;+++[A0A087WXK0_HUMAN|Unreviewed]SubName: Full=Protein PIGBOS1 {ECO:0000313|Ensembl:ENSP00000481097}; Flags: Fragment;"]
[101928589,"'LOC101928589'",58.63,209.89,176.84,148.453333333333,{"$nulls":7},"uncharacterized LOC101928589","[A0A2Y9R3X6_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC111821147 {ECO:0000313|RefSeq:XP_023590205.1};+++[D3DUY5_HUMAN|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX02668.1}; Flags: Fragment;+++[G7NT51_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH30994.1}; Flags: Fragment;+++[G7Q3G6_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH61145.1}; Flags: Fragment;+++[Q9NXL7_HUMAN|diamond]SubName: Full=cDNA FLJ20173 fis, clone COL09814 {ECO:0000313|EMBL:BAA90993.1};"]
[101928601,"'MEI4'",2,1,1,1.33333333333333,{"$nulls":4},"GO:0005694///chromosome+++GO:0000800///lateral element","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0051321///meiotic cell cycle+++GO:0042138///meiotic DNA double-strand break formation+++GO:0048477///oogenesis+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0006310///DNA recombination","meiotic double-stranded break formation protein 4","[MEI4_HUMAN|Reviewed]RecName: Full=Meiosis-specific protein MEI4;"]
[101928635,"'LOC101928635'",13,21,12,15.3333333333333,"01100///Metabolic pathways+++04979///Cholesterol metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++00561///Glycerolipid metabolism+++04976///Bile secretion",null,"M00098///Acylglycerol degradation","R02250///triacylglycerol acylhydrolase Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase 1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid","GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016323///basolateral plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0034364///high-density lipoprotein particle+++GO:0016021///integral component of membrane","GO:0004806///triglyceride lipase activity+++GO:0004620///phospholipase activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0005345///purine nucleobase transmembrane transporter activity+++GO:0015288///porin activity+++GO:0046872///metal ion binding+++GO:0005372///water transmembrane transporter activity+++GO:0004170///dUTP diphosphatase activity+++GO:0046943///carboxylic acid transmembrane transporter activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0000287///magnesium ion binding+++GO:0015265///urea channel activity+++GO:0003677///DNA binding+++GO:0034185///apolipoprotein binding+++GO:0005350///pyrimidine nucleobase transmembrane transporter activity+++GO:0015166///polyol transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0008201///heparin binding+++GO:0051213///dioxygenase activity+++GO:0005275///amine transmembrane transporter activity+++GO:0015254///glycerol channel activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0015837///amine transport+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0006633///fatty acid biosynthetic process+++GO:0007588///excretion+++GO:0046942///carboxylic acid transport+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0034382///chylomicron remnant clearance+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006226///dUMP biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0015791///polyol transport+++GO:0006863///purine nucleobase transport+++GO:0034373///intermediate-density lipoprotein particle remodeling+++GO:0070328///triglyceride homeostasis+++GO:0010468///regulation of gene expression+++GO:0006955///immune response+++GO:0032197///transposition, RNA-mediated+++GO:0010033///response to organic substance+++GO:0006970///response to osmotic stress+++GO:0015855///pyrimidine nucleobase transport+++GO:0030104///water homeostasis+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0046689///response to mercury ion+++GO:0034638///phosphatidylcholine catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0019433///triglyceride catabolic process+++GO:0071320///cellular response to cAMP+++GO:0015793///glycerol transport+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0015722///canalicular bile acid transport+++GO:0046081///dUTP catabolic process+++GO:0006833///water transport+++GO:0043691///reverse cholesterol transport+++GO:0006310///DNA recombination","uncharacterized LOC101928635","[AQP10_MILTA|diamond]RecName: Full=Aquaporin-10 {ECO:0000303|PubMed:23761966}; Short=AQP-10 {ECO:0000303|PubMed:23761966};+++[AQP3_MOUSE|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=Aquaglyceroporin-3;+++[AQP3_RAT|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=31.4 kDa water channel protein; AltName: Full=Aquaglyceroporin-3;+++[AQP9_HUMAN|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9; AltName: Full=Small solute channel 1;+++[AQP9_MOUSE|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[AQP9_RAT|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DUT_HUMAN|diamond]RecName: Full=Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; Short=dUTPase; EC=3.6.1.23; AltName: Full=dUTP pyrophosphatase; Flags: Precursor;+++[DUTL_HUMAN|diamond]RecName: Full=Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323; Short=dUTPase-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LIPC_BOVIN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_HUMAN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_MOUSE|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RABIT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RAT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYL10_HUMAN|diamond]RecName: Full=Myosin regulatory light chain 10; AltName: Full=Myosin light chain 2, lymphocyte-specific; AltName: Full=Precursor lymphocyte-specific regulatory light chain;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928722,"'LOC101928722'",0,0,4,1.33333333333333,{"$nulls":4},"GO:0005813///centrosome","GO:0008017///microtubule binding","GO:0034453///microtubule anchoring","nascent polypeptide-associated complex subunit alpha, muscle-specific form-like","[A0A0D9RT94_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000011833};+++[A0A1W2PQX5_HUMAN|diamond]SubName: Full=Coiled-coil domain-containing protein 187 {ECO:0000313|Ensembl:ENSP00000492326};+++[A0A2I2Z933_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000043611};+++[A0A2R8ZH59_PANPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000003079};+++[H2RG04_PANTR|diamond]SubName: Full=CCDC187 isoform 3 {ECO:0000313|EMBL:PNI68580.1}; SubName: Full=Coiled-coil domain containing 187 {ECO:0000313|Ensembl:ENSPTRP00000060450};"]
[101928764,"'LOC101928764'",7,6,4,5.66666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005604///basement membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:0007154///cell communication+++GO:0048839///inner ear development+++GO:0001654///eye development+++GO:0042733///embryonic digit morphogenesis+++GO:0007507///heart development+++GO:0002009///morphogenesis of an epithelium","coiled-coil domain-containing protein 144B","[FREM2_HUMAN|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; Flags: Precursor;+++[FREM2_MOUSE|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; AltName: Full=NV domain-containing protein 1; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[POTB2_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B2;+++[POTB3_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B3 {ECO:0000312|HGNC:HGNC:51240};+++[POTEA_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member A; AltName: Full=ANKRD26-like family A member 1; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 8; Short=POTE-8;+++[POTEB_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B {ECO:0000305}; AltName: Full=ANKRD26-like family B member 1 {ECO:0000305}; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 15 {ECO:0000303|PubMed:15276201}; Short=POTE-15 {ECO:0000303|PubMed:15276201};+++[POTEC_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member C; AltName: Full=ANKRD26-like family B member 2; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 18; Short=POTE-18;"]
[101928841,"'LOC101928841'",25.63,17,18,20.21,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","collagen alpha-1(II) chain-like","[FIBH_BOMMO|diamond]RecName: Full=Fibroin heavy chain; Short=Fib-H; AltName: Full=H-fibroin; Flags: Precursor;+++[PHXR5_MOUSE|diamond]RecName: Full=Putative per-hexamer repeat protein 5;+++[TPRX1_HUMAN|diamond]RecName: Full=Tetra-peptide repeat homeobox protein 1;+++[TSEP_GLOPP|diamond]RecName: Full=Protein TsetseEP; AltName: Full=EP-repeat protein; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928991,"'CCDC92B'",9.32,8.24,14.02,10.5266666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity",null,"coiled-coil domain containing 92B","[CCD92_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 92; AltName: Full=Limkain beta-2;+++[CCD92_MOUSE|diamond]RecName: Full=Coiled-coil domain-containing protein 92;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929097,"'101929097'",113.6,185.97,165.08,154.883333333333,{"$nulls":8},"[H2NWX9_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000010497};+++[Q9H7L4_HUMAN|diamond]SubName: Full=FLJ00058 protein {ECO:0000313|EMBL:BAB15755.1}; Flags: Fragment;"]
[101929141,"'LOC101929141'",1.08,1.99,0,1.02333333333333,{"$nulls":7},"coiled-coil domain-containing protein 144B-like","[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;+++[C144B_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144B;+++[C144C_HUMAN|diamond]RecName: Full=Putative coiled-coil domain-containing protein 144C; AltName: Full=Coiled-coil domain-containing protein 144C pseudogene;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[POTEE_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member E; AltName: Full=ANKRD26-like family C member 1A; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 2; Short=POTE-2;+++[POTEF_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member F; AltName: Full=ANKRD26-like family C member 1B; AltName: Full=Chimeric POTE-actin protein;"]
[101929235,"'LOC101929235'",0,0,0.5,0.166666666666667,{"$nulls":7},"putative ubiquitin-conjugating enzyme E2Q2-like protein","[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;+++[UB2Q2_BOVIN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_HUMAN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_MOUSE|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_RABIT|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-conjugating enzyme UBCi; AltName: Full=Ubiquitin-protein ligase Q2;"]
[101929322,"'LOC101929322'",300,165.31,287,250.77,{"$nulls":4},"GO:0005829///cytosol+++GO:0032587///ruffle membrane+++GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0016020///membrane","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding","GO:0043410///positive regulation of MAPK cascade+++GO:0000165///MAPK cascade+++GO:0016180///snRNA processing+++GO:0019933///cAMP-mediated signaling+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0006468///protein phosphorylation","integrator complex subunit 4 pseudogene","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[INT4_DICDI|diamond]RecName: Full=Integrator complex subunit 4 homolog;+++[INT4_DROME|diamond]RecName: Full=Integrator complex subunit 4 {ECO:0000303|PubMed:21078872};+++[INT4_HUMAN|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_MOUSE|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_XENLA|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929400,"'LOC101929400'",5.11,3,0,2.70333333333333,{"$nulls":5},"GO:0003723///RNA binding",null,"uncharacterized LOC101929400","[A0A2I2ZER1_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000045561};+++[A0A2I3HCP8_NOMLE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000041428};+++[A0A2I3T7A9_PANTR|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNI44179.1}; SubName: Full=RNA binding fox-1 homolog 1 {ECO:0000313|Ensembl:ENSPTRP00000085111};+++[A0A2J8SEY9_PONAB|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNJ19325.1};+++[A0A2J8SEZ1_PONAB|diamond]SubName: Full=RBFOX1 isoform 24 {ECO:0000313|EMBL:PNJ19336.1};"]
[101929479,"'LOC101929479'",466.37,380.56,414.76,420.563333333333,{"$nulls":4},"GO:0043202///lysosomal lumen+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0032580///Golgi cisterna membrane+++GO:0005796///Golgi lumen+++GO:0031258///lamellipodium membrane+++GO:0000922///spindle pole+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0016324///apical plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0072686///mitotic spindle","GO:0045296///cadherin binding+++GO:0061676///importin-alpha family protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0019905///syntaxin binding+++GO:0019901///protein kinase binding","GO:0007020///microtubule nucleation+++GO:0060050///positive regulation of protein glycosylation+++GO:0001525///angiogenesis+++GO:0006486///protein glycosylation+++GO:0051289///protein homotetramerization+++GO:0051225///spindle assembly+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0010507///negative regulation of autophagy+++GO:0090307///mitotic spindle assembly+++GO:0000187///activation of MAPK activity+++GO:0030207///chondroitin sulfate catabolic process+++GO:0048771///tissue remodeling+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0090161///Golgi ribbon formation+++GO:0090166///Golgi disassembly+++GO:0090306///spindle assembly involved in meiosis+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0032091///negative regulation of protein binding+++GO:0008356///asymmetric cell division+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0008283///cell proliferation+++GO:0007098///centrosome cycle+++GO:0035556///intracellular signal transduction+++GO:0008347///glial cell migration","golgin subfamily A member 2","[CSPG4_HUMAN|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Melanoma chondroitin sulfate proteoglycan; AltName: Full=Melanoma-associated chondroitin sulfate proteoglycan; Flags: Precursor;+++[CSPG4_MOUSE|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Proteoglycan AN2; Flags: Precursor;+++[CSPG4_RAT|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=HSN tumor-specific antigen; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DYN1_BOVIN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_HUMAN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_MOUSE|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_RAT|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5; AltName: Full=B-dynamin; AltName: Full=D100; AltName: Full=Dynamin, brain;+++[GGA2B_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 2B; AltName: Full=Golgin subfamily A member 2-like protein 1;+++[GOG6A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6A; AltName: Full=Golgin linked to PML; AltName: Full=Golgin-like protein;+++[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8A; AltName: Full=88 kDa Golgi matrix protein; Short=GM88; AltName: Full=GM88 autoantigen;+++[GOG8B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8B; AltName: Full=Golgin-67;+++[GOG8C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8C;+++[GOG8D_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POLY_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon gypsy; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;"]
[101929692,"'LOC101929692'",0,0.98,0,0.326666666666667,{"$nulls":7},"uncharacterized LOC101929692"]
[101929747,"'101929747'",7.5,17,5,9.83333333333333,{"$nulls":8},"[A0A2Y9JJD1_ENHLU|diamond]SubName: Full=uncharacterized protein LOC111148452 {ECO:0000313|RefSeq:XP_022360711.1};"]
[101929796,"'NOTCH2NLR'",48.59,59.79,59.91,56.0966666666667,"04330///Notch signaling pathway+++01522///Endocrine resistance+++04658///Th1 and Th2 cell differentiation+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++04320///Dorso-ventral axis formation","H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0005654///nucleoplasm+++GO:0043235///receptor complex+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005576///extracellular region","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007399///nervous system development+++GO:0007219///Notch signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006915///apoptotic process+++GO:0002315///marginal zone B cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007050///cell cycle arrest+++GO:0003184///pulmonary valve morphogenesis+++GO:0046849///bone remodeling+++GO:2001204///regulation of osteoclast development+++GO:0030097///hemopoiesis+++GO:0060413///atrial septum morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0001709///cell fate determination+++GO:0045967///negative regulation of growth rate+++GO:0009887///animal organ morphogenesis+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0061314///Notch signaling involved in heart development+++GO:0019827///stem cell population maintenance+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","notch 2 N-terminal like R","[NOTC2_HUMAN|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Short=hN2; Contains: RecName: Full=Notch 2 extracellular truncation; Short=N2ECD {ECO:0000303|PubMed:25985737}; Contains: RecName: Full=Notch 2 intracellular domain; Short=N2ICD {ECO:0000303|PubMed:25985737}; Flags: Precursor;+++[NOTC2_RAT|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Contains: RecName: Full=Notch 2 extracellular truncation; Contains: RecName: Full=Notch 2 intracellular domain; Flags: Precursor;+++[NT2NA_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[NT2NC_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[101929895,"'LOC101929895'",14,8,9,10.3333333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0043209///myelin sheath+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0008017///microtubule binding+++GO:0015631///tubulin binding","GO:0031334///positive regulation of protein complex assembly+++GO:0001578///microtubule bundle formation+++GO:0046785///microtubule polymerization+++GO:0032273///positive regulation of protein polymerization","uncharacterized LOC101929895","[TPPP_BOVIN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=p25-alpha;+++[TPPP_HUMAN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=TPPP/p25; AltName: Full=p24; AltName: Full=p25-alpha;+++[TPPP_MOUSE|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP;"]
[101929937,"'LOC101929937'",0,0,3,1,null,"H00773///Autosomal dominant mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0032993///protein-DNA complex+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0030133///transport vesicle","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0021510///spinal cord development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045165///cell fate commitment+++GO:0065004///protein-DNA complex assembly","uncharacterized LOC101929937","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[NRSN2_HUMAN|diamond]RecName: Full=Neurensin-2;+++[NRSN2_MOUSE|diamond]RecName: Full=Neurensin-2;+++[SOX11_CHICK|diamond]RecName: Full=Transcription factor SOX-11; Short=cSox11;+++[SOX11_XENTR|diamond]RecName: Full=Transcription factor Sox-11;+++[SOX12_HUMAN|diamond]RecName: Full=Transcription factor SOX-12; AltName: Full=Protein SOX-22;+++[SOX12_MOUSE|diamond]RecName: Full=Transcription factor SOX-12;+++[SX11B_XENLA|diamond]RecName: Full=Transcription factor Sox-11-B; AltName: Full=Transcription factor Sox-13; Short=xSox-13; AltName: Full=XLS13B;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929950,"'LOC101929950'",6.68,12.07,11.77,10.1733333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0042277///peptide binding","GO:0006508///proteolysis+++GO:0043171///peptide catabolic process","puromycin-sensitive aminopeptidase-like protein","[ERAP1_MOUSE|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 1; EC=3.4.11.-; AltName: Full=ARTS-1; AltName: Full=Adipocyte-derived leucine aminopeptidase; Short=A-LAP; AltName: Full=Aminopeptidase PILS; AltName: Full=Puromycin-insensitive leucyl-specific aminopeptidase; Short=PILS-AP; AltName: Full=VEGF-induced aminopeptidase;+++[ERAP2_BOVIN|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 2; EC=3.4.11.-;+++[PSA_CAEEL|diamond]RecName: Full=Puromycin-sensitive aminopeptidase {ECO:0000303|PubMed:12930831}; Short=PSA {ECO:0000305}; EC=3.4.11.14 {ECO:0000305|PubMed:12930831}; AltName: Full=Cytosol alanyl aminopeptidase {ECO:0000305}; Short=AAP-S {ECO:0000305};+++[PSA_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;+++[PSAL_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase-like protein; EC=3.4.11.-;+++[PSA_MOUSE|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;"]
[101929959,"'LOC101929959'",163.35,128.52,130.46,140.776666666667,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++03320///PPAR signaling pathway+++04140///Autophagy - animal+++04923///Regulation of lipolysis in adipocytes","H02106///Genetic obesity+++H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0030686///90S preribosome+++GO:0005730///nucleolus","GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0003723///RNA binding+++GO:0035252///UDP-xylosyltransferase activity+++GO:0034511///U3 snoRNA binding+++GO:0015267///channel activity+++GO:0003924///GTPase activity","GO:0006364///rRNA processing+++GO:0000479///endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0016266///O-glycan processing","ribosome biogenesis protein BMS1 homolog","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[AQP7_HUMAN|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7; AltName: Full=Aquaporin adipose; Short=AQPap; AltName: Full=Aquaporin-7-like;+++[AQP7_MACFA|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[AQP7_MOUSE|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[BMS1_HUMAN|diamond]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GXLT1_HUMAN|diamond]RecName: Full=Glucoside xylosyltransferase 1; EC=2.4.2.n2; AltName: Full=Glycosyltransferase 8 domain-containing protein 3;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[TSR1_DICDI|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_HUMAN|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_MOUSE|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_PONAB|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_XENLA|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10193,"'RNF41'",1230.91,1114.05,1073.52,1139.49333333333,"04144///Endocytosis",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0071782///endoplasmic reticulum tubular network","GO:0004842///ubiquitin-protein transferase activity+++GO:0019904///protein domain specific binding+++GO:0017160///Ral GTPase binding+++GO:0005128///erythropoietin receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0005135///interleukin-3 receptor binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity","GO:0010498///proteasomal protein catabolic process+++GO:0051896///regulation of protein kinase B signaling+++GO:0051865///protein autoubiquitination+++GO:0006915///apoptotic process+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000114///regulation of establishment of cell polarity+++GO:0006914///autophagy+++GO:0045637///regulation of myeloid cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0010468///regulation of gene expression+++GO:1901525///negative regulation of mitophagy+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045619///regulation of lymphocyte differentiation+++GO:0000209///protein polyubiquitination+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0008285///negative regulation of cell proliferation+++GO:0043408///regulation of MAPK cascade+++GO:0016567///protein ubiquitination","ring finger protein 41","[RNF41_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase NRDP1; EC=2.3.2.27; AltName: Full=RING finger protein 41; AltName: Full=RING-type E3 ubiquitin transferase NRDP1 {ECO:0000305};+++[A0A024RB33_HUMAN|Unreviewed]SubName: Full=Ring finger protein 41, isoform CRA_b {ECO:0000313|EMBL:EAW96911.1};+++[F8VNZ6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000450164}; Flags: Fragment;+++[F8VSB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448187};+++[F8VSE5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448330};+++[F8VSP7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000446595}; Flags: Fragment;+++[F8VVY2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000449575};"]
[101930047,"'LOC101930047'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0032587///ruffle membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0008022///protein C-terminus binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0005524///ATP binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0071889///14-3-3 protein binding","GO:0043405///regulation of MAP kinase activity+++GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0019933///cAMP-mediated signaling","uncharacterized protein FLJ46347-like","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[KSR2_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 2; Short=hKSR2; EC=2.7.11.1;+++[KSR2_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 2; EC=2.7.11.1;"]
[101930307,"'LOC101930307'",28,14,20,20.6666666666667,{"$nulls":4},"GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity","GO:0008152///metabolic process","uncharacterized LOC101930307","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10194,"'TSHZ1'",161,129,158,149.333333333333,"04391///Hippo signaling pathway - fly","H02115///Congenital aural atresia",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0009952///anterior/posterior pattern specification+++GO:0007275///multicellular organism development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060023///soft palate development+++GO:0042474///middle ear morphogenesis","teashirt zinc finger homeobox 1","[TSH1_HUMAN|Reviewed]RecName: Full=Teashirt homolog 1; AltName: Full=Antigen NY-CO-33; AltName: Full=Serologically defined colon cancer antigen 33;+++[A7YF73_HUMAN|Unreviewed]SubName: Full=TSHZ1 protein {ECO:0000313|EMBL:AAH24152.2}; Flags: Fragment;+++[H0YKA1_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000452718}; Flags: Fragment;+++[H0YN23_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000453834}; Flags: Fragment;"]
[10195,"'ALG3'",1822,2112,2027,1987,"00513///Various types of N-glycan biosynthesis+++00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R06258///Dolichyl phosphate D-mannose + G00006 <=> Dolichyl phosphate + G10595","GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0005515///protein binding+++GO:0052925///dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0000030///mannosyltransferase activity+++GO:0000033///alpha-1,3-mannosyltransferase activity","GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006486///protein glycosylation+++GO:0097502///mannosylation","ALG3, alpha-1,3- mannosyltransferase","[ALG3_HUMAN|Reviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; EC=2.4.1.258; AltName: Full=Asparagine-linked glycosylation protein 3 homolog; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase; AltName: Full=Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase; AltName: Full=Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase; AltName: Full=Not56-like protein;+++[C9J7S5_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047};+++[F8WE30_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000394917};+++[F8WF93_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000407011};+++[H7BZZ2_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000392209}; Flags: Fragment;+++[H7C0X4_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; Flags: Fragment;"]
[10196,"'PRMT3'",90,55,98,81,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,null,"R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol","GO:0008168///methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0043022///ribosome binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0034969///histone arginine methylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032259///methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006479///protein methylation","protein arginine methyltransferase 3","[ANM3_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 3; EC=2.1.1.-; AltName: Full=Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3;+++[E9PLF6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000435151};+++[E9PRB4_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000434260};+++[Q8WUV3_HUMAN|Unreviewed]SubName: Full=PRMT3 protein {ECO:0000313|EMBL:AAH19339.1}; Flags: Fragment;"]
[10197,"'PSME3'",1999,1875,1924,1932.66666666667,"03050///Proteasome+++05160///Hepatitis C+++04612///Antigen processing and presentation",null,null,"R03139///primary-amine oxidase 1,3-Diaminopropane + Oxygen + H2O <=> 3-Aminopropanal + Ammonia + Hydrogen peroxide+++R06740///primary-amine oxidase Cadaverine + H2O + Oxygen <=> 5-Aminopentanal + Ammonia + Hydrogen peroxide+++R02613///Phenethylamine:oxygen oxidoreductase (deaminating) Phenethylamine + Oxygen + H2O <=> Phenylacetaldehyde + Ammonia + Hydrogen peroxide+++R06154///methylamine:oxygen oxidoreductase (deaminating) (copper-containing) Methylamine + Oxygen + H2O <=> Formaldehyde + Ammonia + Hydrogen peroxide+++R02529///aminoacetone:oxygen oxidoreductase(deaminating) Aminoacetone + H2O + Oxygen <=> Methylglyoxal + Ammonia + Hydrogen peroxide+++R02382///Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) Tyramine + H2O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04300///4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing) Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04027///primary-amine oxidase N-Methylputrescine + Oxygen + H+ <=> 1-Methylpyrrolinium + Hydrogen peroxide + Ammonia","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0008537///proteasome activator complex+++GO:0000502///proteasome complex","GO:0061133///endopeptidase activator activity+++GO:0002039///p53 binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007049///cell cycle+++GO:0043687///post-translational protein modification+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0006915///apoptotic process","proteasome activator subunit 3","[PSME3_HUMAN|Reviewed]RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma;+++[A0A024R203_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) activator subunit 3 (PA28 gamma Ki), isoform CRA_a {ECO:0000313|EMBL:EAW60894.1};+++[A0A087WTV2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000478159};+++[B3KQ25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32659 fis, clone TESTI1000045, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAG51887.1};+++[B7Z8D3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57249, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAH13919.1};+++[K7EJF8_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465155};+++[K7EKR3_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465743}; Flags: Fragment;+++[K7EMD0_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466451}; Flags: Fragment;+++[K7ENH2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466945}; Flags: Fragment;+++[K7EPX6_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000467580}; Flags: Fragment;+++[K7ESG5_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000468702};+++[K9J957_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000438237}; SubName: Full=REG gamma-3 variant {ECO:0000313|EMBL:ACO54885.1};+++[Q6FHK7_HUMAN|Unreviewed]SubName: Full=PSME3 protein {ECO:0000313|EMBL:CAG46545.1};+++[Q6MZZ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686J2076 {ECO:0000313|EMBL:CAE45884.1};+++[V9HWJ8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 283 {ECO:0000313|EMBL:ACJ13707.1};"]
[10198,"'MPHOSPH9'",188,151,149,162.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus",null,null,"M-phase phosphoprotein 9","[MPP9_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 9;+++[A0A0A0MTP3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000445859};+++[F5GYG6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440664}; Flags: Fragment;+++[F5GYP5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441298}; Flags: Fragment;+++[F5H1U6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446362}; Flags: Fragment;+++[F5H1W2_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446334}; Flags: Fragment;+++[F5H2I5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446249};+++[F5H798_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000442663};+++[H0YFS3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440007}; Flags: Fragment;+++[H0YG46_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441764}; Flags: Fragment;+++[J3KNE4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000304096}; Flags: Fragment;+++[U3KQ61_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475578}; Flags: Fragment;+++[U3KQD6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475785}; Flags: Fragment;+++[U3KQJ0_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475923}; Flags: Fragment;"]
[10199,"'MPHOSPH10'",314,307,328,316.333333333333,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034457///Mpp10 complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006396///RNA processing+++GO:0042254///ribosome biogenesis+++GO:0010923///negative regulation of phosphatase activity+++GO:0006364///rRNA processing+++GO:0008380///RNA splicing","M-phase phosphoprotein 10","[MPP10_HUMAN|Reviewed]RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10; AltName: Full=M phase phosphoprotein 10;+++[U3KQ48_HUMAN|Unreviewed]SubName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000313|Ensembl:ENSP00000475545};"]
[102,"'ADAM10'",2172,1622,1670,1821.33333333333,"05010///Alzheimer's disease+++05120///Epithelial cell signaling in Helicobacter pylori infection",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0030425///dendrite+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0043025///neuronal cell body+++GO:0070062///extracellular exosome+++GO:0070821///tertiary granule membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0098794///postsynapse+++GO:0005798///Golgi-associated vesicle+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion","GO:0004222///metalloendopeptidase activity+++GO:0019901///protein kinase binding+++GO:0008233///peptidase activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0017124///SH3 domain binding+++GO:0008237///metallopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0008284///positive regulation of cell proliferation+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0034205///amyloid-beta formation+++GO:0030307///positive regulation of cell growth+++GO:0001701///in utero embryonic development+++GO:0007162///negative regulation of cell adhesion+++GO:0043687///post-translational protein modification+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0007219///Notch signaling pathway+++GO:0016485///protein processing+++GO:0051089///constitutive protein ectodomain proteolysis+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0034612///response to tumor necrosis factor+++GO:0007283///spermatogenesis+++GO:0022617///extracellular matrix disassembly+++GO:0051088///PMA-inducible membrane protein ectodomain proteolysis+++GO:0006508///proteolysis+++GO:0007267///cell-cell signaling+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0007229///integrin-mediated signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0097327///response to antineoplastic agent+++GO:0006468///protein phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0043312///neutrophil degranulation+++GO:0099173///postsynapse organization+++GO:0042117///monocyte activation+++GO:0035333///Notch receptor processing, ligand-dependent+++GO:0043065///positive regulation of apoptotic process","ADAM metallopeptidase domain 10","[ADA10_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; EC=3.4.24.81 {ECO:0000269|PubMed:11477090, ECO:0000269|PubMed:12475894, ECO:0000269|PubMed:16239146, ECO:0000269|PubMed:17557115, ECO:0000269|PubMed:19114711, ECO:0000269|PubMed:20592283, ECO:0000269|PubMed:29224781}; AltName: Full=CDw156; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: CD_antigen=CD156c; Flags: Precursor;+++[A0A024R5U5_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase domain 10, isoform CRA_b {ECO:0000313|EMBL:EAW77541.1};+++[A0A087WYG1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000481779};+++[A0AV88_HUMAN|Unreviewed]SubName: Full=ADAM10 protein {ECO:0000313|EMBL:AAI26254.1};+++[B5MC71_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000386056};+++[C9J9B4_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000391930}; Flags: Fragment;+++[H0YK32_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452639};+++[H0YK87_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452704}; Flags: Fragment;+++[H0YNC5_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000453952}; Flags: Fragment;+++[H3BS53_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000456542}; Flags: Fragment;+++[L8E9R5_HUMAN|Unreviewed]SubName: Full=Alternative protein ADAM10 {ECO:0000313|EMBL:CCQ43088.1};"]
[1020,"'CDK5'",369,444,456,423,"05010///Alzheimer's disease+++05030///Cocaine addiction+++04360///Axon guidance","H00268///Lissencephaly (LIS)",null,null,"GO:0005874///microtubule+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0043204///perikaryon+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0098794///postsynapse+++GO:0030424///axon+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane+++GO:0016533///protein kinase 5 complex+++GO:0030425///dendrite+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse","GO:0016301///kinase activity+++GO:0043125///ErbB-3 class receptor binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0002039///p53 binding+++GO:0050321///tau-protein kinase activity+++GO:0000166///nucleotide binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels+++GO:0051879///Hsp90 protein binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0048156///tau protein binding+++GO:0046875///ephrin receptor binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0030549///acetylcholine receptor activator activity+++GO:0005176///ErbB-2 class receptor binding+++GO:0008017///microtubule binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016740///transferase activity","GO:0007399///nervous system development+++GO:0051402///neuron apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008542///visual learning+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0032801///receptor catabolic process+++GO:0000226///microtubule cytoskeleton organization+++GO:0045861///negative regulation of proteolysis+++GO:0098883///synapse pruning+++GO:0032092///positive regulation of protein binding+++GO:0008306///associative learning+++GO:2000273///positive regulation of signaling receptor activity+++GO:0048813///dendrite morphogenesis+++GO:0071156///regulation of cell cycle arrest+++GO:0022038///corpus callosum development+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0008045///motor neuron axon guidance+++GO:0016079///synaptic vesicle exocytosis+++GO:0042220///response to cocaine+++GO:0008283///cell proliferation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0009611///response to wounding+++GO:0048489///synaptic vesicle transport+++GO:0070509///calcium ion import+++GO:0048812///neuron projection morphogenesis+++GO:0021695///cerebellar cortex development+++GO:0016241///regulation of macroautophagy+++GO:1904646///cellular response to amyloid-beta+++GO:0006886///intracellular protein transport+++GO:0035418///protein localization to synapse+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0021766///hippocampus development+++GO:0045860///positive regulation of protein kinase activity+++GO:0034352///positive regulation of glial cell apoptotic process+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:0031397///negative regulation of protein ubiquitination+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0007049///cell cycle+++GO:0030182///neuron differentiation+++GO:0046826///negative regulation of protein export from nucleus+++GO:0016572///histone phosphorylation+++GO:0030900///forebrain development+++GO:0048167///regulation of synaptic plasticity+++GO:0031175///neuron projection development+++GO:0048148///behavioral response to cocaine+++GO:0035249///synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0045055///regulated exocytosis+++GO:0007409///axonogenesis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0042501///serine phosphorylation of STAT protein+++GO:0006915///apoptotic process+++GO:0051301///cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0019233///sensory perception of pain+++GO:0014044///Schwann cell development+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0021697///cerebellar cortex formation+++GO:0006913///nucleocytoplasmic transport+++GO:0007519///skeletal muscle tissue development+++GO:0007005///mitochondrion organization+++GO:0021537///telencephalon development+++GO:0045786///negative regulation of cell cycle+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0048709///oligodendrocyte differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007160///cell-matrix adhesion+++GO:0021987///cerebral cortex development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0021954///central nervous system neuron development+++GO:0021819///layer formation in cerebral cortex+++GO:0048675///axon extension+++GO:0043113///receptor clustering+++GO:0006468///protein phosphorylation+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0001764///neuron migration+++GO:0021549///cerebellum development+++GO:1903421///regulation of synaptic vesicle recycling+++GO:0001963///synaptic transmission, dopaminergic+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0016477///cell migration+++GO:0030517///negative regulation of axon extension+++GO:0048511///rhythmic process+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0007416///synapse assembly+++GO:0016310///phosphorylation","cyclin dependent kinase 5","[CDK5_HUMAN|Reviewed]RecName: Full=Cyclin-dependent-like kinase 5; EC=2.7.11.1; AltName: Full=Cell division protein kinase 5; AltName: Full=Serine/threonine-protein kinase PSSALRE; AltName: Full=Tau protein kinase II catalytic subunit; Short=TPKII catalytic subunit;+++[A0A090N7W4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 {ECO:0000313|EMBL:EAL24498.1}; SubName: Full=Cyclin-dependent kinase 5 isoform 1 {ECO:0000313|EMBL:ALQ33426.1}; SubName: Full=Cyclin-dependent kinase 5, isoform CRA_a {ECO:0000313|EMBL:EAW54049.1};+++[A0A0S2Z355_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 isoform 2 {ECO:0000313|EMBL:ALQ33427.1}; Flags: Fragment;+++[Q6IAW3_HUMAN|Unreviewed]SubName: Full=CDK5 protein {ECO:0000313|EMBL:CAG33322.1};"]
[10200,"'MPHOSPH6'",86,108,98,97.3333333333333,"03018///RNA degradation",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0000178///exosome (RNase complex)+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0030165///PDZ domain binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0000460///maturation of 5.8S rRNA+++GO:0065003///protein-containing complex assembly","M-phase phosphoprotein 6","[MPH6_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 6 {ECO:0000305};+++[H3BNK8_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6, isoform CRA_b {ECO:0000313|EMBL:EAW95517.1};+++[H3BNT4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000454996};+++[H3BSB3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000456626};+++[H3BU96_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000457537};"]
[10201,"'NME6'",256,244,266,255.333333333333,"04016///MAPK signaling pathway - plant+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00230///Purine metabolism",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase   ATP + dCDP <=> ADP + dCTP+++R00124///ATP:ADP phosphatransferase   ATP + ADP <=> ADP + ATP+++R00156///ATP:UDP phosphotransferase   ATP + UDP <=> ADP + UTP+++R00330///ATP:GDP phosphotransferase   ATP + GDP <=> ADP + GTP+++R01857///ATP:dGDP phosphotransferase   ATP + dGDP <=> ADP + dGTP+++R00570///ATP:CDP phosphotransferase   ATP + CDP <=> ADP + CTP+++R11895///ATP:5-fluorodeoxyuridine-diphosphate phosphotransferase   ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate+++R01137///ATP:dADP phosphotransferase   ATP + dADP <=> ADP + dATP+++R02331///ATP:dUDP phosphotransferase   ATP + dUDP <=> ADP + dUTP+++R02093///ATP:dTDP phosphotransferase   ATP + dTDP <=> ADP + dTTP+++R00139///ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase   2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP+++R00722///ATP:IDP phosphotransferase   ATP + IDP <=> ADP + ITP+++R11894///ATP:5-fluorouridine-diphosphate phosphotransferase   ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate+++R03530///ATP:dIDP phosphotransferase   ATP + dIDP <=> ADP + dITP","GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0045839///negative regulation of mitotic nuclear division+++GO:0016310///phosphorylation+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0030308///negative regulation of cell growth+++GO:0006228///UTP biosynthetic process+++GO:0006915///apoptotic process","NME/NM23 nucleoside diphosphate kinase 6","[NDK6_HUMAN|Reviewed]RecName: Full=Nucleoside diphosphate kinase 6; Short=NDK 6; Short=NDP kinase 6; EC=2.7.4.6; AltName: Full=Inhibitor of p53-induced apoptosis-alpha; Short=IPIA-alpha; AltName: Full=nm23-H6;+++[A0A0C4DG91_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y547_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y7V2_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[C9J1J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000392715}; Flags: Fragment;+++[C9J867_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000405755}; Flags: Fragment;+++[C9J9V6_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013}; Flags: Fragment;+++[C9JQB1_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[F2Z2J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000410435};"]
[10202,"'DHRS2'",15,21,9,15,{"$nulls":4},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix","GO:0016491///oxidoreductase activity+++GO:0004090///carbonyl reductase (NADPH) activity+++GO:0005515///protein binding","GO:0008285///negative regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0009636///response to toxic substance+++GO:0055114///oxidation-reduction process+++GO:0043011///myeloid dendritic cell differentiation+++GO:0034599///cellular response to oxidative stress","dehydrogenase/reductase 2","[DHRS2_HUMAN|Reviewed]RecName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial; EC=1.1.1.-; AltName: Full=Dicarbonyl reductase HEP27; AltName: Full=Protein D; AltName: Full=Short chain dehydrogenase/reductase family 25C member 1; Flags: Precursor;+++[C9JZP6_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000401213}; Flags: Fragment;+++[H0YJG9_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451485}; Flags: Fragment;+++[H0YJP4_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451895}; Flags: Fragment;"]
[10203,"'CALCRL'",1,0,0,0.333333333333333,"04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:1990406///CGRP receptor complex+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:1903143///adrenomedullin receptor complex","GO:1990409///adrenomedullin binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0004930///G protein-coupled receptor activity+++GO:0001605///adrenomedullin receptor activity+++GO:0004948///calcitonin receptor activity","GO:0045986///negative regulation of smooth muscle contraction+++GO:0007507///heart development+++GO:0001525///angiogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0031623///receptor internalization+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0006816///calcium ion transport+++GO:0015031///protein transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway+++GO:0071329///cellular response to sucrose stimulus+++GO:0050728///negative regulation of inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","calcitonin receptor like receptor","[CALRL_HUMAN|Reviewed]RecName: Full=Calcitonin gene-related peptide type 1 receptor; Short=CGRP type 1 receptor; AltName: Full=Calcitonin receptor-like receptor; Flags: Precursor;+++[B8ZZJ4_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000386599}; Flags: Fragment;+++[D3DPG9_HUMAN|Unreviewed]SubName: Full=Calcitonin receptor-like, isoform CRA_a {ECO:0000313|EMBL:EAX10926.1};+++[E7EN01_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000415626}; Flags: Fragment;"]
[10204,"'NUTF2'",3231,3351,3084,3222,{"$nulls":4},"GO:0044613///nuclear pore central transport channel+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0005637///nuclear inner membrane+++GO:0005643///nuclear pore+++GO:0005640///nuclear outer membrane","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0017056///structural constituent of nuclear pore","GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0042307///positive regulation of protein import into nucleus+++GO:0090204///protein localization to nuclear pore+++GO:1904046///negative regulation of vascular endothelial growth factor production+++GO:0015031///protein transport+++GO:0000060///protein import into nucleus, translocation+++GO:0006913///nucleocytoplasmic transport","nuclear transport factor 2","[NTF2_HUMAN|Reviewed]RecName: Full=Nuclear transport factor 2 {ECO:0000303|PubMed:7744965}; Short=NTF-2; AltName: Full=Placental protein 15 {ECO:0000303|PubMed:3380696}; Short=PP15 {ECO:0000303|PubMed:3380696};+++[A0A024R6Y2_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2, isoform CRA_a {ECO:0000313|EMBL:EAW83182.1};+++[H3BRV9_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2 {ECO:0000313|Ensembl:ENSP00000456428}; Flags: Fragment;"]
[10205,"'MPZL2'",6,4,16,8.66666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0009653///anatomical structure morphogenesis+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","myelin protein zero like 2","[MPZL2_HUMAN|Reviewed]RecName: Full=Myelin protein zero-like protein 2; AltName: Full=Epithelial V-like antigen 1; Flags: Precursor;+++[A0A024R3K1_HUMAN|Unreviewed]SubName: Full=Epithelial V-like antigen 1, isoform CRA_a {ECO:0000313|EMBL:EAW67359.1};"]
[10206,"'TRIM13'",242.45,194.03,232.94,223.14,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0005737///cytoplasm+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:1902187///negative regulation of viral release from host cell+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0010332///response to gamma radiation+++GO:0016239///positive regulation of macroautophagy+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0002376///immune system process+++GO:0051865///protein autoubiquitination+++GO:0009653///anatomical structure morphogenesis+++GO:0010942///positive regulation of cell death+++GO:0016567///protein ubiquitination+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0045087///innate immune response+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:0032897///negative regulation of viral transcription","tripartite motif containing 13","[TRI13_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM13; EC=2.3.2.27; AltName: Full=B-cell chronic lymphocytic leukemia tumor suppressor Leu5; AltName: Full=Leukemia-associated protein 5; AltName: Full=Putative tumor suppressor RFP2; AltName: Full=RING finger protein 77; AltName: Full=RING-type E3 ubiquitin transferase TRIM13 {ECO:0000305}; AltName: Full=Ret finger protein 2; AltName: Full=Tripartite motif-containing protein 13;+++[A0A024RDU3_HUMAN|Unreviewed]SubName: Full=Ret finger protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX08848.1};+++[A0A184AP76_HUMAN|Unreviewed]SubName: Full=Putative tumor suppressor RFP2 {ECO:0000313|EMBL:ABE41638.1};+++[L7MTJ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAD38633.1}; Flags: Fragment;+++[L8E9D0_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM13 {ECO:0000313|EMBL:CCQ43336.1};+++[X6R9U5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000367425}; Flags: Fragment;+++[X6RH27_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000404586}; Flags: Fragment;"]
[10207,"'PATJ'",261,182,225,222.666666666667,"04390///Hippo signaling pathway+++05165///Human papillomavirus infection+++04530///Tight junction",{"$nulls":3},"GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0045177///apical part of cell+++GO:0032991///protein-containing complex+++GO:0005923///bicellular tight junction+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0035556///intracellular signal transduction+++GO:0070830///bicellular tight junction assembly","PATJ, crumbs cell polarity complex component","[INADL_HUMAN|Reviewed]RecName: Full=InaD-like protein; Short=Inadl protein; Short=hINADL; AltName: Full=Pals1-associated tight junction protein; AltName: Full=Protein associated to tight junctions;+++[A0A087WUZ6_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000479041};+++[A0A0U1RQR3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489130}; Flags: Fragment;+++[A0A0U1RQT2_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489159};+++[A0A0U1RQW4_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489200}; Flags: Fragment;+++[A0A0U1RR46_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489335};+++[A0A0U1RRD7_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489475}; Flags: Fragment;+++[A0A0X1KG69_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000326199};+++[A0A2R8Y549_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494277};+++[A0A2R8Y5I3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494824};+++[A5PKX9_HUMAN|Unreviewed]SubName: Full=INADL protein {ECO:0000313|EMBL:AAI42662.1};+++[B4DE90_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59473, highly similar to InaD-like protein {ECO:0000313|EMBL:BAG57001.1};"]
[10208,"'USPL1'",184,132,168,161.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0070140///SUMO-specific isopeptidase activity+++GO:0043130///ubiquitin binding","GO:0030576///Cajal body organization+++GO:0009301///snRNA transcription+++GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0008283///cell proliferation","ubiquitin specific peptidase like 1","[USPL1_HUMAN|Reviewed]RecName: Full=SUMO-specific isopeptidase USPL1; EC=3.4.22.-; AltName: Full=Ubiquitin-specific peptidase-like protein 1; Short=USP-like 1;+++[A8K1B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75211, highly similar to Homo sapiens ubiquitin specific peptidase like 1, mRNA {ECO:0000313|EMBL:BAF82515.1};+++[B3KQ64_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32952 fis, clone TESTI2008081, highly similar to Homo sapiens D13S106 a highly charged amino acid sequence {ECO:0000313|EMBL:BAG51926.1}; Flags: Fragment;+++[L8ECC7_HUMAN|Unreviewed]SubName: Full=Alternative protein USPL1 {ECO:0000313|EMBL:CCQ43337.1};"]
[10209,"'EIF1'",2678,3031,2531,2746.66666666667,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding","GO:0006412///translation+++GO:0006446///regulation of translational initiation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0006413///translational initiation","eukaryotic translation initiation factor 1","[EIF1_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1; Short=eIF1; AltName: Full=A121; AltName: Full=Protein translation factor SUI1 homolog; AltName: Full=Sui1iso1;+++[K7EM18_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000466321};+++[K7EQP2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000467918}; Flags: Fragment;+++[Q6IAV3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW60754.1}; SubName: Full=Putative translation initiation factor {ECO:0000313|EMBL:AAP35291.1}; SubName: Full=SUI1 protein {ECO:0000313|EMBL:CAG33332.1}; SubName: Full=cDNA, FLJ92128, Homo sapiens putative translation initiation factor (SUI1), mRNA {ECO:0000313|EMBL:BAG34803.1};"]
[1021,"'CDK6'",1991,1384,1320,1565,"05218///Melanoma+++05224///Breast cancer+++04110///Cell cycle+++05200///Pathways in cancer+++05214///Glioma+++04218///Cellular senescence+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05162///Measles+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04151///PI3K-Akt signaling pathway+++05223///Non-small cell lung cancer+++05163///Human cytomegalovirus infection+++04934///Cushing's syndrome+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++05161///Hepatitis B+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++05212///Pancreatic cancer","H00269///Primary microcephaly (MCPH)","M00692///Cell cycle - G1/S transition",null,"GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0001726///ruffle+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0098770///FBXO family protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0030332///cyclin binding+++GO:0016740///transferase activity","GO:0050680///negative regulation of epithelial cell proliferation+++GO:0043697///cell dedifferentiation+++GO:0007049///cell cycle+++GO:0048699///generation of neurons+++GO:0045668///negative regulation of osteoblast differentiation+++GO:2000145///regulation of cell motility+++GO:0045656///negative regulation of monocyte differentiation+++GO:0014002///astrocyte development+++GO:0003323///type B pancreatic cell development+++GO:0009615///response to virus+++GO:0051301///cell division+++GO:0042063///gliogenesis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0021670///lateral ventricle development+++GO:0045596///negative regulation of cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0006468///protein phosphorylation+++GO:0045646///regulation of erythrocyte differentiation+++GO:0030154///cell differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0021542///dentate gyrus development+++GO:0010468///regulation of gene expression+++GO:0045786///negative regulation of cell cycle+++GO:0007050///cell cycle arrest","cyclin dependent kinase 6","[CDK6_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 6; EC=2.7.11.22; AltName: Full=Cell division protein kinase 6; AltName: Full=Serine/threonine-protein kinase PLSTIRE;"]
[10210,"'TOPORS'",458,395,397,416.666666666667,null,"H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005814///centriole+++GO:0000151///ubiquitin ligase complex+++GO:0000930///gamma-tubulin complex+++GO:0030496///midbody+++GO:0032391///photoreceptor connecting cilium+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005868///cytoplasmic dynein complex+++GO:0036064///ciliary basal body+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0019789///SUMO transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0044547///DNA topoisomerase binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003823///antigen binding","GO:0000209///protein polyubiquitination+++GO:0034504///protein localization to nucleus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006351///transcription, DNA-templated+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0042127///regulation of cell proliferation+++GO:0016925///protein sumoylation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0010842///retina layer formation+++GO:0046548///retinal rod cell development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0035845///photoreceptor cell outer segment organization+++GO:0051457///maintenance of protein location in nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0046549///retinal cone cell development+++GO:0006513///protein monoubiquitination","TOP1 binding arginine/serine rich protein","[TOPRS_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Topors; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase Topors {ECO:0000305}; AltName: Full=SUMO1-protein E3 ligase Topors; AltName: Full=Topoisomerase I-binding RING finger protein; AltName: Full=Topoisomerase I-binding arginine/serine-rich protein; AltName: Full=Tumor suppressor p53-binding protein 3; Short=p53-binding protein 3; Short=p53BP3;"]
[10211,"'FLOT1'",1221,1289,1203,1237.66666666667,"04910///Insulin signaling pathway",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0044853///plasma membrane raft+++GO:0042383///sarcolemma+++GO:0016600///flotillin complex+++GO:0005815///microtubule organizing center+++GO:0048786///presynaptic active zone+++GO:0005765///lysosomal membrane+++GO:0098793///presynapse+++GO:0042470///melanosome+++GO:0030027///lamellipodium+++GO:0005768///endosome+++GO:0045121///membrane raft+++GO:0005913///cell-cell adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0044291///cell-cell contact zone+++GO:0098978///glutamatergic synapse+++GO:0005901///caveola+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0001931///uropod+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0098982///GABA-ergic synapse+++GO:0016324///apical plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0008180///COP9 signalosome+++GO:0098691///dopaminergic synapse+++GO:0034451///centriolar satellite+++GO:0030864///cortical actin cytoskeleton+++GO:0005769///early endosome","GO:0046982///protein heterodimerization activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0002020///protease binding+++GO:0005515///protein binding","GO:1903044///protein localization to membrane raft+++GO:0032728///positive regulation of interferon-beta production+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0001765///membrane raft assembly+++GO:1901890///positive regulation of cell junction assembly+++GO:0022617///extracellular matrix disassembly+++GO:0051580///regulation of neurotransmitter uptake+++GO:0070528///protein kinase C signaling+++GO:0007409///axonogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0050821///protein stabilization+++GO:1901741///positive regulation of myoblast fusion+++GO:0051260///protein homooligomerization+++GO:0044854///plasma membrane raft assembly+++GO:0034976///response to endoplasmic reticulum stress+++GO:0033227///dsRNA transport+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0002090///regulation of receptor internalization+++GO:0045807///positive regulation of endocytosis+++GO:0035023///regulation of Rho protein signal transduction+++GO:0001819///positive regulation of cytokine production+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034143///regulation of toll-like receptor 4 signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071360///cellular response to exogenous dsRNA+++GO:0032226///positive regulation of synaptic transmission, dopaminergic","flotillin 1","[FLOT1_HUMAN|Reviewed]RecName: Full=Flotillin-1;+++[A0A0G2JJQ6_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000409995}; Flags: Fragment;+++[A0A140T905_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388153}; Flags: Fragment;+++[A0A140T907_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388104}; Flags: Fragment;+++[A0A140T910_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388517}; Flags: Fragment;+++[A0A140T957_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393145}; Flags: Fragment;+++[A0A140T959_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000392736}; Flags: Fragment;+++[A0A140T974_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393767}; Flags: Fragment;+++[A0A140T9B1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000397108}; Flags: Fragment;+++[A0A140T9C3_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398866}; Flags: Fragment;+++[A0A140T9H7_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000403574}; Flags: Fragment;+++[A0A140T9L9_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000407101}; Flags: Fragment;+++[A0A140T9R1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000410658}; Flags: Fragment;+++[A0A140T9W4_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415215}; Flags: Fragment;+++[A0A140T9X0_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415104}; Flags: Fragment;+++[A2AB09_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000395333}; Flags: Fragment;+++[A2AB10_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000400615}; Flags: Fragment;+++[A2AB11_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000412058}; Flags: Fragment;+++[A2AB12_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398834}; Flags: Fragment;+++[A2AB13_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000391341}; Flags: Fragment;+++[A2ABJ5_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000404300}; Flags: Fragment;+++[A2VCL5_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:AAI28155.1}; Flags: Fragment;+++[Q5ST80_HUMAN|Unreviewed]SubName: Full=FLOT1 {ECO:0000313|EMBL:AQY76816.1}; SubName: Full=FLOT1 protein {ECO:0000313|EMBL:BAF31269.1}; SubName: Full=Flotillin 1 {ECO:0000313|EMBL:AAP35740.1}; SubName: Full=Flotillin 1, isoform CRA_b {ECO:0000313|EMBL:EAX03326.1};+++[Q6IB58_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:CAG33227.1};"]
[10212,"'DDX39A'",277,285,292,284.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing","DExD-box helicase 39A","[DX39A_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX39A; EC=3.6.4.13; AltName: Full=DEAD box protein 39; AltName: Full=Nuclear RNA helicase URH49;+++[A0A024R7H0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, isoform CRA_b {ECO:0000313|EMBL:EAW84416.1};+++[A0A0D9SEM9_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000485838}; Flags: Fragment;+++[K7EIL8_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000464801}; Flags: Fragment;+++[K7EL56_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000465926}; Flags: Fragment;+++[K7EN69_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000466810}; Flags: Fragment;+++[K7ENP6_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467040}; Flags: Fragment;+++[K7EPJ3_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467411}; Flags: Fragment;+++[K7EQN7_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467911}; Flags: Fragment;"]
[10213,"'PSMD14'",463,410,424,432.333333333333,"05169///Epstein-Barr virus infection+++03050///Proteasome",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0031597///cytosolic proteasome complex+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0000502///proteasome complex+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0034774///secretory granule lumen+++GO:0005634///nucleus+++GO:0022624///proteasome accessory complex+++GO:1904813///ficolin-1-rich granule lumen","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0061133///endopeptidase activator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070628///proteasome binding+++GO:0016787///hydrolase activity","GO:0006281///DNA repair+++GO:0043312///neutrophil degranulation+++GO:0070536///protein K63-linked deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010950///positive regulation of endopeptidase activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006508///proteolysis+++GO:0000724///double-strand break repair via homologous recombination+++GO:0043687///post-translational protein modification+++GO:0045471///response to ethanol+++GO:0016579///protein deubiquitination+++GO:0061136///regulation of proteasomal protein catabolic process","proteasome 26S subunit, non-ATPase 14","[PSDE_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 14; EC=3.4.19.-; AltName: Full=26S proteasome regulatory subunit RPN11; AltName: Full=26S proteasome-associated PAD1 homolog 1;+++[A0A140VKF2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 69n {ECO:0000313|EMBL:AEE61289.1};+++[C9JW37_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 14 {ECO:0000313|Ensembl:ENSP00000399311}; Flags: Fragment;+++[Q4ZG77_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAX88940.1}; Flags: Fragment;+++[Q53TH1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAY15016.1}; Flags: Fragment;"]
[102157402,"'AK6'",58.57,58.74,64.23,60.5133333333333,"00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03008///Ribosome biogenesis in eukaryotes",null,"M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R00127///ATP:AMP phosphotransferase   ATP + AMP <=> 2 ADP+++R01547///ATP:dAMP phosphotransferase   ATP + dAMP <=> ADP + dADP","GO:0000790///nuclear chromatin+++GO:0005669///transcription factor TFIID complex+++GO:0031389///Rad17 RFC-like complex+++GO:0005737///cytoplasm+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000125///PCAF complex+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003713///transcription coactivator activity+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005524///ATP binding+++GO:0033613///activating transcription factor binding+++GO:0051117///ATPase binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0003689///DNA clamp loader activity+++GO:0003682///chromatin binding+++GO:0050145///nucleoside monophosphate kinase activity+++GO:0004017///adenylate kinase activity+++GO:0016887///ATPase activity","GO:0030307///positive regulation of cell growth+++GO:0043966///histone H3 acetylation+++GO:0033314///mitotic DNA replication checkpoint+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008156///negative regulation of DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000492///box C/D snoRNP assembly+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0000077///DNA damage checkpoint+++GO:0006366///transcription by RNA polymerase II+++GO:0042325///regulation of phosphorylation+++GO:0050821///protein stabilization+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0070555///response to interleukin-1+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0043066///negative regulation of apoptotic process+++GO:0006260///DNA replication+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0000076///DNA replication checkpoint+++GO:0007093///mitotic cell cycle checkpoint","adenylate kinase 6","[KAD6_HUMAN|Reviewed]RecName: Full=Adenylate kinase isoenzyme 6 {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK6 {ECO:0000255|HAMAP-Rule:MF_03173}; EC=2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03173}; AltName: Full=Adrenal gland protein AD-004; AltName: Full=Coilin-interacting nuclear ATPase protein {ECO:0000255|HAMAP-Rule:MF_03173}; Short=hCINAP; AltName: Full=Dual activity adenylate kinase/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK/ATPase {ECO:0000255|HAMAP-Rule:MF_03173};+++[A0A087WVD7_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000479366};+++[A0A087WY94_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000481620};+++[D6RDH4_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000420947};"]
[10216,"'PRG4'",3,1,3,2.33333333333333,{"$nulls":4},"GO:0062023///collagen-containing extracellular matrix","GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0030247///polysaccharide binding+++GO:0005044///scavenger receptor activity","GO:0008283///cell proliferation+++GO:0006955///immune response","proteoglycan 4","[PRG4_HUMAN|Reviewed]RecName: Full=Proteoglycan 4; AltName: Full=Lubricin; AltName: Full=Megakaryocyte-stimulating factor; AltName: Full=Superficial zone proteoglycan; Contains: RecName: Full=Proteoglycan 4 C-terminal part; Flags: Precursor;+++[A0A0U1RR20_HUMAN|Unreviewed]SubName: Full=Proteoglycan 4 {ECO:0000313|Ensembl:ENSP00000489292};"]
[10217,"'CTDSPL'",415,325,410,383.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0016787///hydrolase activity","GO:0016311///dephosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0008150///biological_process","CTD small phosphatase like","[CTDSL_HUMAN|Reviewed]RecName: Full=CTD small phosphatase-like protein; Short=CTDSP-like; EC=3.1.3.16; AltName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; AltName: Full=NIF-like protein; AltName: Full=Nuclear LIM interactor-interacting factor 1; Short=NLI-interacting factor 1; AltName: Full=Protein YA22; Short=hYA22; AltName: Full=RBSP3; AltName: Full=Small C-terminal domain phosphatase 3; Short=SCP3; Short=Small CTD phosphatase 3;+++[A0A024R2L8_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, isoform CRA_c {ECO:0000313|EMBL:EAW64505.1};+++[F8WED2_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000408183};+++[H7C2B9_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000404977}; Flags: Fragment;+++[H7C2S4_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000407443}; Flags: Fragment;+++[H7C353_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000409600}; Flags: Fragment;"]
[10218,"'ANGPTL7'",1442,1321,1147,1303.33333333333,{"$nulls":4},"GO:0005576///extracellular region","GO:0005515///protein binding","GO:0006979///response to oxidative stress","angiopoietin like 7","[ANGL7_HUMAN|Reviewed]RecName: Full=Angiopoietin-related protein 7; AltName: Full=Angiopoietin-like factor; AltName: Full=Angiopoietin-like protein 7; AltName: Full=Cornea-derived transcript 6 protein; Flags: Precursor;"]
[10219,"'KLRG1'",0,6,2,2.66666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0030246///carbohydrate binding+++GO:0042803///protein homodimerization activity+++GO:0038023///signaling receptor activity","GO:0007263///nitric oxide mediated signal transduction+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045087///innate immune response+++GO:0002376///immune system process+++GO:0009749///response to glucose+++GO:0007166///cell surface receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006968///cellular defense response+++GO:0006954///inflammatory response+++GO:0030073///insulin secretion","killer cell lectin like receptor G1","[KLRG1_HUMAN|Reviewed]RecName: Full=Killer cell lectin-like receptor subfamily G member 1; AltName: Full=C-type lectin domain family 15 member A; AltName: Full=ITIM-containing receptor MAFA-L; AltName: Full=MAFA-like receptor; AltName: Full=Mast cell function-associated antigen;+++[F5H207_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily G member 1 {ECO:0000313|Ensembl:ENSP00000445627}; Flags: Fragment;+++[F5H8E3_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily G member 1 {ECO:0000313|Ensembl:ENSP00000443658}; Flags: Fragment;"]
[1022,"'CDK7'",270,295,278,281,"04110///Cell cycle+++03022///Basal transcription factors+++03420///Nucleotide excision repair",null,"M00290///Holo-TFIIH complex",null,"GO:0070985///transcription factor TFIIK complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0003713///transcription coactivator activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0050681///androgen receptor binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008022///protein C-terminus binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0007050///cell cycle arrest+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007049///cell cycle+++GO:0030521///androgen receptor signaling pathway+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0008283///cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0050821///protein stabilization+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006370///7-methylguanosine mRNA capping+++GO:0006468///protein phosphorylation+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016310///phosphorylation+++GO:0006363///termination of RNA polymerase I transcription","cyclin dependent kinase 7","[CDK7_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 7; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=39 kDa protein kinase; Short=p39 Mo15; AltName: Full=CDK-activating kinase 1; AltName: Full=Cell division protein kinase 7; AltName: Full=Serine/threonine-protein kinase 1; AltName: Full=TFIIH basal transcription factor complex kinase subunit;+++[A0A0S2Z3F9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), isoform CRA_a {ECO:0000313|EMBL:EAW51300.1}; SubName: Full=Cyclin-dependent kinase 7 isoform 1 {ECO:0000313|EMBL:ALQ33428.1}; Flags: Fragment;+++[D6R9G1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422121};+++[D6R9Z2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422027};+++[D6RAD4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422737};+++[D6REC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425043}; Flags: Fragment;+++[D6RF14_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000421559};+++[D6RFL0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 isoform 3 {ECO:0000313|EMBL:ALQ33429.1};+++[D6RGG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000426372};+++[D6RI01_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425983};+++[D6RIG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425893};+++[Q14495_HUMAN|Unreviewed]SubName: Full=Protein kinase {ECO:0000313|EMBL:CAA53766.1}; Flags: Fragment;"]
[10220,"'GDF11'",1684,1436,1969,1696.33333333333,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005575///cellular_component+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity","GO:0060021///roof of mouth development+++GO:0007399///nervous system development+++GO:0048593///camera-type eye morphogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0048468///cell development+++GO:0008285///negative regulation of cell proliferation+++GO:0060395///SMAD protein signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010469///regulation of signaling receptor activity+++GO:0043408///regulation of MAPK cascade+++GO:0001501///skeletal system development+++GO:0031016///pancreas development+++GO:0007498///mesoderm development+++GO:0001656///metanephros development+++GO:0021512///spinal cord anterior/posterior patterning+++GO:0048469///cell maturation+++GO:0042981///regulation of apoptotic process+++GO:0009887///animal organ morphogenesis+++GO:0001657///ureteric bud development+++GO:0009952///anterior/posterior pattern specification+++GO:0045596///negative regulation of cell differentiation","growth differentiation factor 11","[GDF11_HUMAN|Reviewed]RecName: Full=Growth/differentiation factor 11 {ECO:0000303|PubMed:10391213}; Short=GDF-11; AltName: Full=Bone morphogenetic protein 11 {ECO:0000303|PubMed:10075854}; Short=BMP-11; Flags: Precursor;+++[A0A024RB20_HUMAN|Unreviewed]SubName: Full=Growth differentiation factor 11, isoform CRA_a {ECO:0000313|EMBL:EAW96831.1};+++[H0YI30_HUMAN|Unreviewed]SubName: Full=Growth/differentiation factor 11 {ECO:0000313|Ensembl:ENSP00000448390}; Flags: Fragment;"]
[10221,"'TRIB1'",440,354,364,386,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004860///protein kinase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0055106///ubiquitin-protein transferase regulator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0005524///ATP binding","GO:0006469///negative regulation of protein kinase activity+++GO:0006468///protein phosphorylation+++GO:0045659///negative regulation of neutrophil differentiation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043405///regulation of MAP kinase activity+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0007254///JNK cascade+++GO:0032496///response to lipopolysaccharide+++GO:0045645///positive regulation of eosinophil differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0045651///positive regulation of macrophage differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation","tribbles pseudokinase 1","[TRIB1_HUMAN|Reviewed]RecName: Full=Tribbles homolog 1; Short=TRB-1; AltName: Full=G-protein-coupled receptor-induced gene 2 protein; Short=GIG-2; AltName: Full=SKIP1;+++[E5RFH4_HUMAN|Unreviewed]SubName: Full=Tribbles homolog 1 {ECO:0000313|Ensembl:ENSP00000428879};"]
[10223,"'GPA33'",9,3,1,4.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0038023///signaling receptor activity",null,"glycoprotein A33","[GPA33_HUMAN|Reviewed]RecName: Full=Cell surface A33 antigen; AltName: Full=Glycoprotein A33; Flags: Precursor;+++[A0A0J9YXH7_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000488407}; Flags: Fragment;+++[E9PMB2_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000431195};"]
[10224,"'ZNF443'",6.32,11,10.18,9.16666666666667,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 443","[ZN443_HUMAN|Reviewed]RecName: Full=Zinc finger protein 443; AltName: Full=Krueppel-type zinc finger protein ZK1;+++[F8WDY2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 443 {ECO:0000313|Ensembl:ENSP00000389105};"]
[10225,"'CD96'",5,9.49,8.69,7.72666666666667,null,"H01008///C syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm+++GO:0005912///adherens junction+++GO:0005886///plasma membrane",null,"GO:0007160///cell-matrix adhesion+++GO:0002728///negative regulation of natural killer cell cytokine production+++GO:0006955///immune response+++GO:0032496///response to lipopolysaccharide+++GO:0002534///cytokine production involved in inflammatory response+++GO:0007155///cell adhesion+++GO:0032689///negative regulation of interferon-gamma production+++GO:0050776///regulation of immune response","CD96 molecule","[TACT_HUMAN|Reviewed]RecName: Full=T-cell surface protein tactile; AltName: Full=Cell surface antigen CD96; AltName: Full=T cell-activated increased late expression protein; AltName: CD_antigen=CD96; Flags: Precursor;+++[E9PEJ1_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417152};+++[F8WDV3_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417680};+++[H7C4F0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417150}; Flags: Fragment;+++[L8EAH0_HUMAN|Unreviewed]SubName: Full=Alternative protein CD96 {ECO:0000313|EMBL:CCQ43338.1};+++[Q8WUE2_HUMAN|Unreviewed]SubName: Full=CD96 antigen, isoform CRA_b {ECO:0000313|EMBL:EAW79697.1}; SubName: Full=CD96 protein {ECO:0000313|EMBL:AAH20749.1}; SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000389801};+++[U3KPT0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000475194}; Flags: Fragment;"]
[10226,"'PLIN3'",1431,1443,1149,1341,{"$nulls":4},"GO:0010008///endosome membrane+++GO:0030133///transport vesicle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005768///endosome","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0016192///vesicle-mediated transport","perilipin 3","[PLIN3_HUMAN|Reviewed]RecName: Full=Perilipin-3; AltName: Full=47 kDa mannose 6-phosphate receptor-binding protein; Short=47 kDa MPR-binding protein; AltName: Full=Cargo selection protein TIP47; AltName: Full=Mannose-6-phosphate receptor-binding protein 1; AltName: Full=Placental protein 17; Short=PP17;+++[A0A140VJN8_HUMAN|Unreviewed]RecName: Full=Perilipin {ECO:0000256|PIRNR:PIRNR036881};+++[K7EJD0_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465117}; Flags: Fragment;+++[K7EL96_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465975}; Flags: Fragment;+++[K7ER39_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468096}; Flags: Fragment;+++[K7ERZ3_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468476}; Flags: Fragment;"]
[10227,"'MFSD10'",1867,2206,1894,1989,{"$nulls":4},"GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016021///integral component of membrane","GO:0008514///organic anion transmembrane transporter activity+++GO:0008493///tetracycline transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006915///apoptotic process+++GO:0043252///sodium-independent organic anion transport+++GO:0015904///tetracycline transport","major facilitator superfamily domain containing 10","[MFS10_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 10; AltName: Full=Tetracycline transporter-like protein;+++[D6R9N3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423509};+++[D6RA47_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423402};+++[D6RE79_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000426907};+++[D6RHV1_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000427637};+++[D6RIZ4_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000425757};"]
[10228,"'STX6'",493,422,430,448.333333333333,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0000139///Golgi membrane+++GO:0005769///early endosome+++GO:0030136///clathrin-coated vesicle+++GO:0005654///nucleoplasm+++GO:0032588///trans-Golgi network membrane+++GO:0045335///phagocytic vesicle+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0008021///synaptic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0031201///SNARE complex","GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0016192///vesicle-mediated transport+++GO:0032880///regulation of protein localization+++GO:0048278///vesicle docking+++GO:0032456///endocytic recycling+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0006906///vesicle fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048193///Golgi vesicle transport+++GO:0090161///Golgi ribbon formation+++GO:0007032///endosome organization+++GO:1903827///regulation of cellular protein localization+++GO:0016189///synaptic vesicle to endosome fusion","syntaxin 6","[STX6_HUMAN|Reviewed]RecName: Full=Syntaxin-6;"]
[102288414,"'C11orf98'",498.67,623.01,437.08,519.586666666667,{"$nulls":7},"chromosome 11 open reading frame 98","[CK098_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf98 {ECO:0000305};+++[A0A0B4J220_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 48, isoform CRA_c {ECO:0000313|EMBL:EAW74054.1};+++[L0R588_HUMAN|Unreviewed]SubName: Full=Alternative protein C11orf48 {ECO:0000313|EMBL:CCO13689.1};"]
[10229,"'COQ7'",182,165,195,180.666666666667,"01100///Metabolic pathways+++00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01110///Biosynthesis of secondary metabolites","H00999///Coenzyme Q10 deficiency","M00128///Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone","R08775///2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O+++R04984///2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O","GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008682///2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity+++GO:0004497///monooxygenase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008340///determination of adult lifespan+++GO:0006744///ubiquinone biosynthetic process+++GO:0042493///response to drug+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0055114///oxidation-reduction process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000377///regulation of reactive oxygen species metabolic process","coenzyme Q7, hydroxylase","[COQ7_HUMAN|Reviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000255|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000255|HAMAP-Rule:MF_03194}; Flags: Precursor;+++[H3BP28_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[H3BS11_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456490};+++[H3BSZ3_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456943}; Flags: Fragment;+++[H3BTN8_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457256}; Flags: Fragment;+++[I3L1T0_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000459076}; SubName: Full=Coenzyme Q7 homolog, ubiquinone (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW50269.1};+++[Q49A71_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[Q8NI45_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};"]
[10231,"'RCAN2'",632,500,503,545,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity+++GO:0005515///protein binding","GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0019722///calcium-mediated signaling","regulator of calcineurin 2","[RCAN2_HUMAN|Reviewed]RecName: Full=Calcipressin-2; AltName: Full=Down syndrome candidate region 1-like 1; AltName: Full=Myocyte-enriched calcineurin-interacting protein 2; Short=MCIP2; AltName: Full=Regulator of calcineurin 2; AltName: Full=Thyroid hormone-responsive protein ZAKI-4;+++[A0A0A0MSB6_HUMAN|Unreviewed]SubName: Full=Calcipressin-2 {ECO:0000313|Ensembl:ENSP00000384317};+++[A8MXP8_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000378347};+++[B2R612_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92723, highly similar to Homo sapiens Down syndrome critical region gene 1-like 1 (DSCR1L1), mRNA {ECO:0000313|EMBL:BAG35309.1};+++[H0YL43_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000453052}; Flags: Fragment;+++[L0R6N1_HUMAN|Unreviewed]SubName: Full=Alternative protein RCAN2 {ECO:0000313|EMBL:CCO13800.1};+++[L8E7F0_HUMAN|Unreviewed]SubName: Full=Alternative protein RCN2 {ECO:0000313|EMBL:CCQ43195.1};+++[Q86YJ0_HUMAN|Unreviewed]SubName: Full=RCAN2 protein {ECO:0000313|EMBL:AAH38509.1};"]
[10232,"'MSLN'",63,58,57,59.3333333333333,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0044267///cellular protein metabolic process+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0031016///pancreas development+++GO:0043687///post-translational protein modification","mesothelin","[MSLN_HUMAN|Reviewed]RecName: Full=Mesothelin; AltName: Full=CAK1 antigen; AltName: Full=Pre-pro-megakaryocyte-potentiating factor; Contains: RecName: Full=Megakaryocyte-potentiating factor; Short=MPF; Contains: RecName: Full=Mesothelin, cleaved form; Flags: Precursor;+++[H3BMA1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000454295}; Flags: Fragment;+++[H3BR90_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000456132}; Flags: Fragment;+++[H3BUX1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000457847}; Flags: Fragment;+++[H3BV92_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000458003}; Flags: Fragment;"]
[10233,"'LRRC23'",105,121,126,117.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","leucine rich repeat containing 23","[LRC23_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 23; AltName: Full=Leucine-rich protein B7;+++[A8K8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77436, highly similar to Homo sapiens B7 gene (B7), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF85056.1};+++[C9JEW3_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000396049};+++[C9JKE8_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000402554};+++[C9JQN5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000408066}; Flags: Fragment;+++[E9PDZ4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000397192};+++[F2Z299_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000392623};"]
[10234,"'LRRC17'",1202,1143,643,996,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space",null,"GO:0033687///osteoblast proliferation+++GO:0048539///bone marrow development+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0001649///osteoblast differentiation+++GO:0001503///ossification","leucine rich repeat containing 17","[LRC17_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 17; AltName: Full=p37NB; Flags: Precursor;+++[C9JT74_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 17 {ECO:0000313|Ensembl:ENSP00000394194}; Flags: Fragment;"]
[10235,"'RASGRP2'",20,20,19,19.6666666666667,"04062///Chemokine signaling pathway+++04015///Rap1 signaling pathway+++04010///MAPK signaling pathway+++05200///Pathways in cancer+++04014///Ras signaling pathway+++04611///Platelet activation","H01235///Bleeding disorder platelet-type",null,null,"GO:0043005///neuron projection+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0008289///lipid binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0001558///regulation of cell growth+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0071277///cellular response to calcium ion","RAS guanyl releasing protein 2","[GRP2_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 2; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor I; Short=CalDAG-GEFI; AltName: Full=Cdc25-like protein; Short=hCDC25L; AltName: Full=F25B3.3 kinase-like protein;+++[A6NHE2_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366705}; Flags: Fragment;+++[A6NJ28_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366706};+++[A8MTF9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377950};+++[A8MVK8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377949};+++[B3KV60_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16161 fis, clone BRCAN2012110, highly similar to Homo sapiens RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53672.1};+++[C9JKH6_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000389068}; Flags: Fragment;+++[C9JZ82_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000401314}; Flags: Fragment;+++[E7EM78_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399114}; Flags: Fragment;+++[E7EMB4_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399028};+++[E7EWQ7_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000396029};+++[Q2YDB1_HUMAN|Unreviewed]SubName: Full=RASGRP2 protein {ECO:0000313|EMBL:AAI10307.1}; Flags: Fragment;"]
[10236,"'HNRNPR'",1398,1180,1187,1255,{"$nulls":4},"GO:0071013///catalytic step 2 spliceosome+++GO:0005737///cytoplasm+++GO:0043679///axon terminus+++GO:0030426///growth cone+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005681///spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0030425///dendrite","GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0061157///mRNA destabilization+++GO:0043086///negative regulation of catalytic activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process+++GO:0061014///positive regulation of mRNA catabolic process","heterogeneous nuclear ribonucleoprotein R","[HNRPR_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein R; Short=hnRNP R;+++[A0A286YEZ8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|Ensembl:ENSP00000493186}; Flags: Fragment;+++[B4DMB1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53358, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59823.1};+++[B4DMD1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53360, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59843.1};+++[B4DT28_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R, isoform CRA_a {ECO:0000313|EMBL:EAW95040.1}; SubName: Full=cDNA FLJ54544, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG61840.1};+++[Q0VGD6_HUMAN|Unreviewed]SubName: Full=HNRPR protein {ECO:0000313|EMBL:AAI10390.1}; Flags: Fragment;+++[Q6MZS5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686A13234 {ECO:0000313|EMBL:CAE45953.1}; Flags: Fragment;"]
[10237,"'SLC35B1'",468,467,475,470,{"$nulls":4},"GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005459///UDP-galactose transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:0008643///carbohydrate transport","solute carrier family 35 member B1","[S35B1_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member B1; AltName: Full=UDP-galactose transporter-related protein 1; Short=UGTrel1; Short=hUGTrel1;+++[D3DTX1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35, member B1, isoform CRA_a {ECO:0000313|EMBL:EAW94669.1};+++[D6R981_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000423323}; Flags: Fragment;+++[D6R9G9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000422104}; Flags: Fragment;+++[D6RB73_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424367}; Flags: Fragment;+++[D6RDY9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000425179};+++[D6RE58_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426961}; Flags: Fragment;+++[D6RF81_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424857}; Flags: Fragment;+++[D6RG34_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426402}; Flags: Fragment;+++[D6RHG0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000427689}; Flags: Fragment;"]
[10238,"'DCAF7'",1535.88,1220.1,1549.62,1435.2,{"$nulls":4},"GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0043687///post-translational protein modification","DDB1 and CUL4 associated factor 7","[DCAF7_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 7; AltName: Full=WD repeat-containing protein 68; AltName: Full=WD repeat-containing protein An11 homolog;+++[A0A087WWI6_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 7 {ECO:0000313|Ensembl:ENSP00000480250}; Flags: Fragment;"]
[10239,"'AP3S2'",229.75,395.06,296.23,307.013333333333,"04142///Lysosome",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0030123///AP-3 adaptor complex+++GO:1904115///axon cytoplasm+++GO:0030117///membrane coat+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus",null,"GO:0048490///anterograde synaptic vesicle transport+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport","adaptor related protein complex 3 subunit sigma 2","[AP3S2_HUMAN|Reviewed]RecName: Full=AP-3 complex subunit sigma-2; AltName: Full=AP-3 complex subunit sigma-3B; AltName: Full=Adaptor-related protein complex 3 subunit sigma-2; AltName: Full=Sigma-3B-adaptin; Short=Sigma3B-adaptin; AltName: Full=Sigma-adaptin 3b;+++[A0A024RC62_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_a {ECO:0000313|EMBL:EAX02073.1};+++[A0A087WY05_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000481434};+++[H0YKM3_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000452862};+++[H0YLI7_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453223}; SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_d {ECO:0000313|EMBL:EAX02075.1};+++[H0YLX6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453380};+++[H0YN38_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[H0YNI6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000454027};+++[Q6PK37_HUMAN|Unreviewed]SubName: Full=AP3S2 protein {ECO:0000313|EMBL:AAH07773.1}; Flags: Fragment;"]
[1024,"'CDK8'",363,245,275,294.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016592///mediator complex+++GO:0032991///protein-containing complex","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0006468///protein phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016310///phosphorylation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051726///regulation of cell cycle","cyclin dependent kinase 8","[CDK8_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 8; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cell division protein kinase 8; AltName: Full=Mediator complex subunit CDK8; AltName: Full=Mediator of RNA polymerase II transcription subunit CDK8; AltName: Full=Protein kinase K35;+++[A0A0D9SEP3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000485883}; Flags: Fragment;+++[A0A0D9SFZ2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000487013}; Flags: Fragment;+++[F5H6D4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000437696};+++[Q64FY6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:AAU29339.1};+++[U4PPA3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:CDI06887.1}; Flags: Fragment;"]
[10240,"'MRPS31'",131,115,127,124.333333333333,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05202///Transcriptional misregulation in cancer+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04910///Insulin signaling pathway+++05200///Pathways in cancer+++05215///Prostate cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++04922///Glucagon signaling pathway+++04919///Thyroid hormone signaling pathway+++04068///FoxO signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++05165///Human papillomavirus infection+++04218///Cellular senescence","H00037///Alveolar rhabdomyosarcoma","M00676///PI3K-Akt signaling",null,"GO:0005763///mitochondrial small ribosomal subunit+++GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0005730///nucleolus","GO:0003735///structural constituent of ribosome+++GO:0019904///protein domain specific binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation","mitochondrial ribosomal protein S31","[RT31_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S31, mitochondrial; Short=MRP-S31; Short=S31mt; AltName: Full=Imogen 38; AltName: Full=Mitochondrial small ribosomal subunit protein mS31 {ECO:0000303|PubMed:25838379}; Flags: Precursor;"]
[10241,"'CALCOCO2'",1443,1375,1882,1566.66666666667,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0000421///autophagosome membrane+++GO:0005776///autophagosome+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0016032///viral process+++GO:0034341///response to interferon-gamma+++GO:1901098///positive regulation of autophagosome maturation+++GO:0006914///autophagy+++GO:0098792///xenophagy","calcium binding and coiled-coil domain 2","[CACO2_HUMAN|Reviewed]RecName: Full=Calcium-binding and coiled-coil domain-containing protein 2; AltName: Full=Antigen nuclear dot 52 kDa protein; AltName: Full=Nuclear domain 10 protein NDP52 {ECO:0000305}; Short=Nuclear domain 10 protein 52 {ECO:0000303|PubMed:7540613}; AltName: Full=Nuclear dot protein 52 {ECO:0000303|PubMed:9230084};+++[D6RBF9_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424169}; Flags: Fragment;+++[D6RBI4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422697}; Flags: Fragment;+++[D6REB0_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425090}; Flags: Fragment;+++[D6RF70_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424889}; Flags: Fragment;+++[D6RJE7_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425692}; Flags: Fragment;+++[H0Y9G3_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424083}; Flags: Fragment;+++[H0YBP4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429963}; Flags: Fragment;+++[I3L493_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461083}; Flags: Fragment;+++[I3L4E1_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461184};"]
[10243,"'GPHN'",108,96,114,106,"00790///Folate biosynthesis+++01100///Metabolic pathways+++04727///GABAergic synapse","H00192///Xanthinuria+++H00769///Hyperekplexia",null,"R09735///adenylyl-molybdopterin:molybdate molybdate transferase (AMP-forming)   Adenylated molybdopterin + Molybdate <=> Molybdoenzyme molybdenum cofactor + AMP + H2O+++R09726///ATP:molybdopterin adenylyltransferase   ATP + Molybdopterin <=> Diphosphate + Adenylated molybdopterin","GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0099634///postsynaptic specialization membrane+++GO:0005856///cytoskeleton+++GO:0099572///postsynaptic specialization+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0005829///cytosol","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0061598///molybdopterin adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0008940///nitrate reductase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0061599///molybdopterin molybdotransferase activity+++GO:0043546///molybdopterin cofactor binding","GO:0018315///molybdenum incorporation into molybdenum-molybdopterin complex+++GO:0055114///oxidation-reduction process+++GO:0032324///molybdopterin cofactor biosynthetic process+++GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0007529///establishment of synaptic specificity at neuromuscular junction+++GO:0008152///metabolic process+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0010038///response to metal ion+++GO:0072579///glycine receptor clustering+++GO:0097112///gamma-aminobutyric acid receptor clustering","gephyrin","[GEPH_HUMAN|Reviewed]RecName: Full=Gephyrin {ECO:0000303|PubMed:10839351}; Includes: RecName: Full=Molybdopterin adenylyltransferase; Short=MPT adenylyltransferase; EC=2.7.7.75 {ECO:0000305|PubMed:26613940}; AltName: Full=Domain G; Includes: RecName: Full=Molybdopterin molybdenumtransferase; Short=MPT Mo-transferase; EC=2.10.1.1 {ECO:0000305|PubMed:22040219, ECO:0000305|PubMed:26613940}; AltName: Full=Domain E;+++[F5H039_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000438404};+++[G3V355_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451056};+++[G3V4D2_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451725};+++[G3V4R0_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451935};+++[G3V582_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452220};+++[H0YIY4_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450442}; Flags: Fragment;+++[H0YJ30_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450706}; Flags: Fragment;+++[H0YJR5_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452009}; Flags: Fragment;"]
[10244,"'RABEPK'",220,259,231,236.666666666667,"04141///Protein processing in endoplasmic reticulum+++03060///Protein export+++04918///Thyroid hormone synthesis+++05020///Prion diseases",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0005737///cytoplasm","GO:0051082///unfolded protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0051787///misfolded protein binding+++GO:0019904///protein domain specific binding+++GO:0043022///ribosome binding+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0016887///ATPase activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051087///chaperone binding","GO:0006904///vesicle docking involved in exocytosis+++GO:0006898///receptor-mediated endocytosis","Rab9 effector protein with kelch motifs","[RABEK_HUMAN|Reviewed]RecName: Full=Rab9 effector protein with kelch motifs; AltName: Full=40 kDa Rab9 effector protein; AltName: Full=p40;+++[A0A024R8A0_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 1 {ECO:0000313|EMBL:ALQ33965.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_c {ECO:0000313|EMBL:EAW87619.1};+++[A0A0S2Z4Z1_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 5 {ECO:0000313|EMBL:ALQ33969.1}; Flags: Fragment;+++[A0A0S2Z4Z5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 4 {ECO:0000313|EMBL:ALQ33968.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_d {ECO:0000313|EMBL:EAW87617.1}; Flags: Fragment;+++[A0A0S2Z506_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 3 {ECO:0000313|EMBL:ALQ33967.1};+++[A0A0S2Z553_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 2 {ECO:0000313|EMBL:ALQ33966.1};+++[Q5T1S4_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000362645};+++[Q5T1S5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000402234}; Flags: Fragment;"]
[10245,"'TIMM17B'",408,486,493,462.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane","GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport","translocase of inner mitochondrial membrane 17B","[TI17B_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B;+++[Q8NCS3_HUMAN|Unreviewed]SubName: Full=TIMM17B protein {ECO:0000313|EMBL:AAH29446.1}; Flags: Fragment;+++[V9GYK7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000476861};+++[V9GYS0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477027};+++[V9GYU0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477085}; Flags: Fragment;"]
[10247,"'RIDA'",87,90,76,84.3333333333333,{"$nulls":3},"R11099///2-iminopropanoate aminohydrolase   2-Iminopropanoate + H2O <=> Pyruvate + Ammonia+++R11098///2-iminobutanoate aminohydrolase   2-Iminobutanoate + H2O <=> 2-Oxobutanoate + Ammonia","GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0042803///protein homodimerization activity+++GO:0036041///long-chain fatty acid binding+++GO:1904013///xenon atom binding+++GO:0016787///hydrolase activity+++GO:0046914///transition metal ion binding+++GO:0003723///RNA binding+++GO:0016892///endoribonuclease activity, producing 3'-phosphomonoesters+++GO:0043167///ion binding+++GO:0019239///deaminase activity+++GO:1904012///platinum binding","GO:1901565///organonitrogen compound catabolic process+++GO:0001822///kidney development+++GO:0019518///L-threonine catabolic process to glycine+++GO:1902074///response to salt+++GO:0070314///G1 to G0 transition+++GO:0017148///negative regulation of translation+++GO:0030324///lung development+++GO:0007420///brain development+++GO:0033993///response to lipid+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","reactive intermediate imine deaminase A homolog","[RIDA_HUMAN|Reviewed]RecName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000305|PubMed:22094463}; EC=3.5.99.10 {ECO:0000269|PubMed:22094463}; AltName: Full=14.5 kDa translational inhibitor protein {ECO:0000303|PubMed:8973653}; Short=hp14.5 {ECO:0000303|PubMed:14997576}; Short=p14.5 {ECO:0000303|PubMed:8973653}; AltName: Full=Heat-responsive protein 12 {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Reactive intermediate imine deaminase A homolog {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Translation inhibitor L-PSP ribonuclease {ECO:0000250|UniProtKB:P52759}; EC=3.1.-.- {ECO:0000250|UniProtKB:P52759}; AltName: Full=UK114 antigen homolog {ECO:0000305|PubMed:20817725};+++[A0A024R9H2_HUMAN|Unreviewed]SubName: Full=Heat-responsive protein 12, isoform CRA_a {ECO:0000313|EMBL:EAW91775.1};+++[E5RIP8_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000429321};+++[H0YB34_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000428596}; Flags: Fragment;+++[H0YBX3_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000430482}; Flags: Fragment;"]
[10248,"'POP7'",346,503,408,419,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005634///nucleus+++GO:0000172///ribonuclease MRP complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005654///nucleoplasm","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0001682///tRNA 5'-leader removal+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0008033///tRNA processing","POP7 homolog, ribonuclease P/MRP subunit","[POP7_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p20; Short=RNaseP protein p20; EC=3.1.26.5; AltName: Full=Ribonucleases P/MRP protein subunit POP7 homolog; Short=hPOP7;+++[C9JYM0_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p20 {ECO:0000313|Ensembl:ENSP00000387814}; Flags: Fragment;"]
[1025,"'CDK9'",802,702,770,758,"05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005694///chromosome+++GO:0016020///membrane+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0008023///transcription elongation factor complex+++GO:0000790///nuclear chromatin+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0001223///transcription coactivator binding+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0017069///snRNA binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0004672///protein kinase activity+++GO:0030332///cyclin binding+++GO:0097322///7SK snRNA binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0031297///replication fork processing+++GO:0031056///regulation of histone modification+++GO:0006468///protein phosphorylation+++GO:0007346///regulation of mitotic cell cycle+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0071157///negative regulation of cell cycle arrest+++GO:1903839///positive regulation of mRNA 3'-UTR binding+++GO:0016310///phosphorylation+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0006282///regulation of DNA repair+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0042493///response to drug+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0051147///regulation of muscle cell differentiation+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0033129///positive regulation of histone phosphorylation+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0050434///positive regulation of viral transcription","cyclin dependent kinase 9","[CDK9_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 9; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=C-2K; AltName: Full=Cell division cycle 2-like protein kinase 4; AltName: Full=Cell division protein kinase 9; AltName: Full=Serine/threonine-protein kinase PITALRE; AltName: Full=Tat-associated kinase complex catalytic subunit;+++[A0A024R880_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 (CDC2-related kinase), isoform CRA_a {ECO:0000313|EMBL:EAW87697.1};+++[B5BU53_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|EMBL:BAG70103.1};+++[X6RE90_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|Ensembl:ENSP00000395872}; Flags: Fragment;"]
[10250,"'SRRM1'",2377,2184,2222,2261,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006405///RNA export from nucleus+++GO:0031124///mRNA 3'-end processing+++GO:0006406///mRNA export from nucleus","serine and arginine repetitive matrix 1","[SRRM1_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 1; AltName: Full=SR-related nuclear matrix protein of 160 kDa; Short=SRm160; AltName: Full=Ser/Arg-related nuclear matrix protein;+++[A0A0S2Z4W1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 1 {ECO:0000313|EMBL:ALQ33970.1}; SubName: Full=Serine/arginine repetitive matrix 1, isoform CRA_a {ECO:0000313|EMBL:EAW95138.1}; Flags: Fragment;+++[A0A0S2Z4Z6_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 2 {ECO:0000313|EMBL:ALQ33971.1}; Flags: Fragment;+++[A9Z1X7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000363510};+++[B7Z7U0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61739, highly similar to Serine/arginine repetitive matrix protein 1 {ECO:0000313|EMBL:BAH13726.1};+++[E9PCT1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000391430};+++[M0QXG5_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000469151}; Flags: Fragment;+++[M0R088_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471084}; Flags: Fragment;+++[M0R1E7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471819};"]
[10251,"'SPRY3'",59,30,41,43.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function","GO:0061564///axon development+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046580///negative regulation of Ras protein signal transduction","sprouty RTK signaling antagonist 3","[SPY3_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 3; Short=Spry-3;+++[Q6ZUP3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43494 fis, clone PEBLM2000170, moderately similar to Sprouty homolog 3 {ECO:0000313|EMBL:BAC86177.1};"]
[10252,"'SPRY1'",71,45,89,68.3333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0009966///regulation of signal transduction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0001656///metanephros development+++GO:0007275///multicellular organism development+++GO:0001759///organ induction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0001657///ureteric bud development+++GO:0008285///negative regulation of cell proliferation+++GO:0060940///epithelial to mesenchymal transition involved in cardiac fibroblast development+++GO:0060449///bud elongation involved in lung branching","sprouty RTK signaling antagonist 1","[SPY1_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 1; Short=Spry-1;+++[D6REX7_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421622}; Flags: Fragment;+++[D6RHD2_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421036}; Flags: Fragment;+++[D6RIE6_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000425946}; Flags: Fragment;+++[L8E896_HUMAN|Unreviewed]SubName: Full=Alternative protein SPRY1 {ECO:0000313|EMBL:CCQ43339.1};"]
[10253,"'SPRY2'",544,521,576,547,"04013///MAPK signaling pathway - fly+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015630///microtubule cytoskeleton+++GO:0042995///cell projection+++GO:0032587///ruffle membrane+++GO:0005634///nucleus","GO:0043539///protein serine/threonine kinase activator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity","GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0034260///negative regulation of GTPase activity+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0060541///respiratory system development+++GO:0030324///lung development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0016525///negative regulation of angiogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0031345///negative regulation of cell projection organization+++GO:0030335///positive regulation of cell migration+++GO:0060437///lung growth+++GO:0043407///negative regulation of MAP kinase activity+++GO:0007275///multicellular organism development+++GO:0045595///regulation of cell differentiation+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0060425///lung morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0045165///cell fate commitment+++GO:0060449///bud elongation involved in lung branching+++GO:0010628///positive regulation of gene expression+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0042127///regulation of cell proliferation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway","sprouty RTK signaling antagonist 2","[SPY2_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 2; Short=Spry-2;"]
[10254,"'STAM2'",437,363,386,395.333333333333,"04630///Jak-STAT signaling pathway+++04144///Endocytosis",null,"M00408///ESCRT-0 complex",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0033565///ESCRT-0 complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome","GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0036258///multivesicular body assembly+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0061024///membrane organization+++GO:0016236///macroautophagy+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport","signal transducing adaptor molecule 2","[STAM2_HUMAN|Reviewed]RecName: Full=Signal transducing adapter molecule 2; Short=STAM-2; AltName: Full=Hrs-binding protein;"]
[10256,"'CNKSR1'",29,28,41,32.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0007266///Rho protein signal transduction","connector enhancer of kinase suppressor of Ras 1","[CNKR1_HUMAN|Reviewed]RecName: Full=Connector enhancer of kinase suppressor of ras 1; Short=Connector enhancer of KSR 1; AltName: Full=CNK homolog protein 1; Short=CNK1; Short=hCNK1; AltName: Full=Connector enhancer of KSR-like;+++[B4DL25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60656, highly similar to Connector enhancer of kinase suppressor ofras 1 {ECO:0000313|EMBL:BAG59387.1};+++[B4DXN4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59272, highly similar to Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|EMBL:BAG63446.1};+++[E9PIE0_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000432057};+++[E9PS82_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000435880};+++[G3V160_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_a {ECO:0000313|EMBL:EAX07840.1}; SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000431817};+++[H0YDP5_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000434047}; Flags: Fragment;+++[Q53GM7_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1 variant {ECO:0000313|EMBL:BAD96624.1}; SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_b {ECO:0000313|EMBL:EAX07841.1}; Flags: Fragment;"]
[10257,"'ABCC4'",146,140,107,131,"02010///ABC transporters+++04976///Bile secretion+++04024///cAMP signaling pathway+++01523///Antifolate resistance",{"$nulls":3},"GO:0031088///platelet dense granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0016404///15-hydroxyprostaglandin dehydrogenase (NAD+) activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances","GO:0055085///transmembrane transport+++GO:0010243///response to organonitrogen compound+++GO:0060271///cilium assembly+++GO:0008150///biological_process+++GO:0002576///platelet degranulation+++GO:0010033///response to organic substance+++GO:0099131///ATP hydrolysis coupled ion transmembrane transport+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0042493///response to drug+++GO:0014070///response to organic cyclic compound+++GO:0032310///prostaglandin secretion+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0055114///oxidation-reduction process","ATP binding cassette subfamily C member 4","[MRP4_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 4; AltName: Full=ATP-binding cassette sub-family C member 4; AltName: Full=MRP/cMOAT-related ABC transporter; AltName: Full=Multi-specific organic anion transporter B; Short=MOAT-B;+++[A0A2R8Y5Z3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494938}; Flags: Fragment;+++[A0A2R8Y6V8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000495513};+++[A0A2R8YDC1_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494431}; Flags: Fragment;+++[A0A2R8YDG7_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493766};+++[A8K2Q2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77042, highly similar to Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4, mRNA {ECO:0000313|EMBL:BAF83006.1};+++[O75555_HUMAN|Unreviewed]SubName: Full=ABC transporter MOAT-B isoform {ECO:0000313|EMBL:AAC27077.1}; Flags: Fragment;+++[Q8IUA3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 1 {ECO:0000313|EMBL:AAN08629.1}; SubName: Full=ATP-binding cassette subfamily C member 4 variant 3 {ECO:0000313|EMBL:AAN08630.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_a {ECO:0000313|EMBL:EAX08949.1};+++[Q8IWU1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 2 {ECO:0000313|EMBL:AAN08628.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_d {ECO:0000313|EMBL:EAX08952.1}; SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493861};"]
[1026,"'CDKN1A'",13962,16758,12171,14297,"04928///Parathyroid hormone synthesis, secretion and action+++01522///Endocrine resistance+++05219///Bladder cancer+++04921///Oxytocin signaling pathway+++05203///Viral carcinogenesis+++05226///Gastric cancer+++05165///Human papillomavirus infection+++04066///HIF-1 signaling pathway+++05217///Basal cell carcinoma+++04068///FoxO signaling pathway+++04012///ErbB signaling pathway+++05215///Prostate cancer+++05225///Hepatocellular carcinoma+++04934///Cushing's syndrome+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++01524///Platinum drug resistance+++05218///Melanoma+++05166///HTLV-I infection+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++05160///Hepatitis C+++04115///p53 signaling pathway+++05220///Chronic myeloid leukemia+++04110///Cell cycle+++05212///Pancreatic cancer+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05161///Hepatitis B+++05223///Non-small cell lung cancer+++05214///Glioma+++04630///Jak-STAT signaling pathway+++05222///Small cell lung cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05211///Renal cell carcinoma+++04218///Cellular senescence+++05224///Breast cancer+++05163///Human cytomegalovirus infection+++05213///Endometrial cancer+++05216///Thyroid cancer","H00030///Cervical cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0070557///PCNA-p21 complex+++GO:0032991///protein-containing complex+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex","GO:0044877///protein-containing complex binding+++GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019912///cyclin-dependent protein kinase activating kinase activity+++GO:0016301///kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0030332///cyclin binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:0009636///response to toxic substance+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:0090398///cellular senescence+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010243///response to organonitrogen compound+++GO:0072331///signal transduction by p53 class mediator+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0071850///mitotic cell cycle arrest+++GO:0006974///cellular response to DNA damage stimulus+++GO:0055093///response to hyperoxia+++GO:0034198///cellular response to amino acid starvation+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0042326///negative regulation of phosphorylation+++GO:0010165///response to X-ray+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0051412///response to corticosterone+++GO:0014070///response to organic cyclic compound+++GO:0010033///response to organic substance+++GO:0043066///negative regulation of apoptotic process+++GO:0042493///response to drug+++GO:0046685///response to arsenic-containing substance+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0090399///replicative senescence+++GO:0007265///Ras protein signal transduction+++GO:0090400///stress-induced premature senescence+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034605///cellular response to heat+++GO:0045860///positive regulation of protein kinase activity+++GO:0071493///cellular response to UV-B+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0060574///intestinal epithelial cell maturation+++GO:0007050///cell cycle arrest+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0031668///cellular response to extracellular stimulus+++GO:0007346///regulation of mitotic cell cycle+++GO:0051384///response to glucocorticoid+++GO:0031100///animal organ regeneration+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050821///protein stabilization+++GO:0007507///heart development+++GO:0030308///negative regulation of cell growth+++GO:0071479///cellular response to ionizing radiation+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle","cyclin dependent kinase inhibitor 1A","[CDN1A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1; AltName: Full=CDK-interacting protein 1; AltName: Full=Melanoma differentiation-associated protein 6; Short=MDA-6; AltName: Full=p21;+++[A0A024RCX5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_a {ECO:0000313|EMBL:EAX03907.1};"]
[10260,"'DENND4A'",361,221,317.01,299.67,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0006355///regulation of transcription, DNA-templated","DENN domain containing 4A","[MYCPP_HUMAN|Reviewed]RecName: Full=C-myc promoter-binding protein; AltName: Full=DENN domain-containing protein 4A;+++[A0A0U1RR27_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000489304};+++[H3BSA0_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000456605}; Flags: Fragment;+++[H3BTW5_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000457358}; Flags: Fragment;+++[Q05C90_HUMAN|Unreviewed]SubName: Full=DENND4A protein {ECO:0000313|EMBL:AAH28057.1}; Flags: Fragment;"]
[10262,"'SF3B4'",1369,1792,1666,1609,"03040///Spliceosome","H01376///Acrofacial dysostosis","M00352///Spliceosome, U2-snRNP",null,"GO:0005912///adherens junction+++GO:0005913///cell-cell adherens junction+++GO:0045177///apical part of cell+++GO:0016607///nuclear speck+++GO:0005730///nucleolus+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0070160///tight junction+++GO:0030054///cell junction+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0051015///actin filament binding+++GO:0050839///cell adhesion molecule binding+++GO:0003676///nucleic acid binding+++GO:0045296///cadherin binding+++GO:0017016///Ras GTPase binding+++GO:0003723///RNA binding","GO:0061951///establishment of protein localization to plasma membrane+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0034332///adherens junction organization+++GO:0060019///radial glial cell differentiation+++GO:0007267///cell-cell signaling+++GO:0060563///neuroepithelial cell differentiation+++GO:0043547///positive regulation of GTPase activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0007165///signal transduction+++GO:0007155///cell adhesion+++GO:0048872///homeostasis of number of cells+++GO:0034334///adherens junction maintenance+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0032880///regulation of protein localization+++GO:0030336///negative regulation of cell migration+++GO:0048854///brain morphogenesis+++GO:0021987///cerebral cortex development+++GO:1902414///protein localization to cell junction+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0008380///RNA splicing+++GO:0070830///bicellular tight junction assembly+++GO:0021537///telencephalon development","splicing factor 3b subunit 4","[SF3B4_HUMAN|Reviewed]RecName: Full=Splicing factor 3B subunit 4; AltName: Full=Pre-mRNA-splicing factor SF3b 49 kDa subunit; AltName: Full=Spliceosome-associated protein 49; Short=SAP 49;+++[B3KUJ0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39996 fis, clone STOMA2002166, highly similar to Splicing factor 3B subunit 4 {ECO:0000313|EMBL:BAG53452.1};+++[Q5SZ64_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 4 {ECO:0000313|Ensembl:ENSP00000391114}; SubName: Full=Splicing factor 3b, subunit 4, 49kDa {ECO:0000313|EMBL:CAI12647.1}; Flags: Fragment;"]
[10263,"'CDK2AP2'",1098,1331,1174,1201,{"$nulls":4},"GO:0005874///microtubule+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:2000035///regulation of stem cell division","cyclin dependent kinase 2 associated protein 2","[CDKA2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein 2; Short=CDK2-associated protein 2; AltName: Full=DOC-1-related protein; Short=DOC-1R;+++[E9PKR4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000431503};+++[E9PQJ3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000436213};+++[Q6IAV4_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein {ECO:0000256|PIRNR:PIRNR037709};"]
[10265,"'IRX5'",4,0,2,2,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005499///vitamin D binding+++GO:0003677///DNA binding","GO:0048468///cell development+++GO:0060040///retinal bipolar neuron differentiation+++GO:0010468///regulation of gene expression+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0042551///neuron maturation+++GO:0050896///response to stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007601///visual perception+++GO:0008406///gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0002027///regulation of heart rate","iroquois homeobox 5","[IRX5_HUMAN|Reviewed]RecName: Full=Iroquois-class homeodomain protein IRX-5; AltName: Full=Homeodomain protein IRX-2A; AltName: Full=Homeodomain protein IRXB2; AltName: Full=Iroquois homeobox protein 5;+++[A2RRB5_HUMAN|Unreviewed]SubName: Full=IRX5 protein {ECO:0000313|EMBL:AAI31511.1}; SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000483446};+++[H0YML8_HUMAN|Unreviewed]SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000453660};"]
[10266,"'RAMP2'",15,26,21,20.6666666666667,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0150057///amylin receptor complex 2+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005887///integral component of plasma membrane+++GO:0005623///cell+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:1903143///adrenomedullin receptor complex+++GO:0043235///receptor complex","GO:0005515///protein binding+++GO:0001605///adrenomedullin receptor activity+++GO:0008565///protein transporter activity+++GO:0097643///amylin receptor activity+++GO:0015026///coreceptor activity+++GO:1990409///adrenomedullin binding","GO:0043116///negative regulation of vascular permeability+++GO:2001214///positive regulation of vasculogenesis+++GO:0002040///sprouting angiogenesis+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032570///response to progesterone+++GO:0031623///receptor internalization+++GO:0001666///response to hypoxia+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0001570///vasculogenesis+++GO:0006816///calcium ion transport+++GO:0070830///bicellular tight junction assembly+++GO:0008217///regulation of blood pressure+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006886///intracellular protein transport+++GO:0032355///response to estradiol+++GO:0015031///protein transport+++GO:0097084///vascular smooth muscle cell development+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0070831///basement membrane assembly+++GO:0097647///amylin receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0001525///angiogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0034333///adherens junction assembly+++GO:0045766///positive regulation of angiogenesis+++GO:0007565///female pregnancy+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010628///positive regulation of gene expression","receptor activity modifying protein 2","[RAMP2_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 2; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 2; Short=CRLR activity-modifying protein 2; Flags: Precursor;+++[A0A024R1Z2_HUMAN|Unreviewed]SubName: Full=Receptor (Calcitonin) activity modifying protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW60878.1};+++[K7EKQ3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000465725};+++[K7ENJ8_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000466980}; Flags: Fragment;+++[K7EPN3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000467463};"]
[10267,"'RAMP1'",402,396,422,406.666666666667,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:1990406///CGRP receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0150056///amylin receptor complex 1+++GO:0009986///cell surface+++GO:0005623///cell+++GO:0043235///receptor complex+++GO:0005886///plasma membrane","GO:0097643///amylin receptor activity+++GO:1990407///calcitonin gene-related peptide binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0008565///protein transporter activity+++GO:0015026///coreceptor activity+++GO:0005515///protein binding","GO:0060050///positive regulation of protein glycosylation+++GO:0006886///intracellular protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0001525///angiogenesis+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0015031///protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0097647///amylin receptor signaling pathway+++GO:0031623///receptor internalization+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0006816///calcium ion transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway","receptor activity modifying protein 1","[RAMP1_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 1; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 1; Short=CRLR activity-modifying protein 1; Flags: Precursor;+++[E9PC20_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 1 {ECO:0000313|Ensembl:ENSP00000386720};+++[Q53SN3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY24219.1}; Flags: Fragment;+++[Q53T50_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY14674.1}; Flags: Fragment;"]
[10268,"'RAMP3'",0,3,5,2.66666666666667,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005623///cell+++GO:0005764///lysosome+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0016021///integral component of membrane+++GO:1903143///adrenomedullin receptor complex+++GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0150058///amylin receptor complex 3","GO:0008565///protein transporter activity+++GO:0001605///adrenomedullin receptor activity+++GO:0001540///amyloid-beta binding+++GO:0015026///coreceptor activity+++GO:0097643///amylin receptor activity+++GO:0005515///protein binding","GO:0001921///positive regulation of receptor recycling+++GO:0006886///intracellular protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:0086103///G protein-coupled receptor signaling pathway involved in heart process+++GO:0010739///positive regulation of protein kinase A signaling+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0006816///calcium ion transport+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0031623///receptor internalization+++GO:0038041///cross-receptor inhibition within G protein-coupled receptor heterodimer+++GO:0010628///positive regulation of gene expression+++GO:0001525///angiogenesis+++GO:0097647///amylin receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1904645///response to amyloid-beta+++GO:0072659///protein localization to plasma membrane+++GO:0010942///positive regulation of cell death+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:0015031///protein transport","receptor activity modifying protein 3","[RAMP3_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 3; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 3; Short=CRLR activity-modifying protein 3; Flags: Precursor;+++[A4D2L1_HUMAN|Unreviewed]SubName: Full=Receptor (Calcitonin) activity modifying protein 3 {ECO:0000313|EMBL:EAL23743.1}; SubName: Full=Receptor (Calcitonin) activity modifying protein 3, isoform CRA_a {ECO:0000313|EMBL:EAW61048.1}; SubName: Full=cDNA, FLJ92137, Homo sapiens receptor (calcitonin) activity modifying protein 3(RAMP3), mRNA {ECO:0000313|EMBL:BAG34812.1};+++[J3KR56_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 3 {ECO:0000313|Ensembl:ENSP00000418460};+++[L8E7U1_HUMAN|Unreviewed]SubName: Full=Alternative protein RAMP3 {ECO:0000313|EMBL:CCQ43340.1};+++[M5AMS3_HUMAN|Unreviewed]SubName: Full=Receptor (G protein-coupled) activity modifying protein 3 {ECO:0000313|EMBL:BAN10198.1}; Flags: Fragment;+++[M5AP16_HUMAN|Unreviewed]SubName: Full=Receptor (G protein-coupled) activity modifying protein 3 {ECO:0000313|EMBL:BAN10197.1}; Flags: Fragment;"]
[10269,"'ZMPSTE24'",737,558,683,659.333333333333,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis","H00665///Mandibuloacral dysplasia+++H00663///Restrictive dermopathy",null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005635///nuclear envelope+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0004175///endopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0008235///metalloexopeptidase activity+++GO:0016787///hydrolase activity+++GO:0003690///double-stranded DNA binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0046872///metal ion binding","GO:0061337///cardiac conduction+++GO:0051276///chromosome organization+++GO:0060993///kidney morphogenesis+++GO:0003231///cardiac ventricle development+++GO:0003007///heart morphogenesis+++GO:0032006///regulation of TOR signaling+++GO:0032350///regulation of hormone metabolic process+++GO:0006998///nuclear envelope organization+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0040014///regulation of multicellular organism growth+++GO:0003417///growth plate cartilage development+++GO:0010629///negative regulation of gene expression+++GO:1990164///histone H2A phosphorylation+++GO:0090239///regulation of histone H4 acetylation+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:1903522///regulation of blood circulation+++GO:0007628///adult walking behavior+++GO:1903463///regulation of mitotic cell cycle DNA replication+++GO:0050905///neuromuscular process+++GO:0008016///regulation of heart contraction+++GO:0044030///regulation of DNA methylation+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:0006508///proteolysis+++GO:0070302///regulation of stress-activated protein kinase signaling cascade+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0030327///prenylated protein catabolic process+++GO:0071586///CAAX-box protein processing+++GO:0010506///regulation of autophagy+++GO:0001889///liver development+++GO:0010628///positive regulation of gene expression+++GO:0072423///response to DNA damage checkpoint signaling+++GO:0030500///regulation of bone mineralization+++GO:0044029///hypomethylation of CpG island+++GO:0048538///thymus development+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0043969///histone H2B acetylation+++GO:0035264///multicellular organism growth+++GO:0006281///DNA repair+++GO:0048145///regulation of fibroblast proliferation+++GO:0019216///regulation of lipid metabolic process+++GO:0006997///nucleus organization+++GO:0006325///chromatin organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0050688///regulation of defense response to virus+++GO:0008544///epidermis development+++GO:0030282///bone mineralization+++GO:0043007///maintenance of rDNA+++GO:1990036///calcium ion import into sarcoplasmic reticulum+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001942///hair follicle development+++GO:0006925///inflammatory cell apoptotic process+++GO:0008340///determination of adult lifespan+++GO:0016485///protein processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0010906///regulation of glucose metabolic process+++GO:0048739///cardiac muscle fiber development+++GO:2000772///regulation of cellular senescence+++GO:0044255///cellular lipid metabolic process+++GO:0008360///regulation of cell shape+++GO:2000618///regulation of histone H4-K16 acetylation+++GO:0071480///cellular response to gamma radiation+++GO:0043979///histone H2B-K5 acetylation+++GO:2000730///regulation of termination of RNA polymerase I transcription","zinc metallopeptidase STE24","[FACE1_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 1 homolog; EC=3.4.24.84; AltName: Full=Farnesylated proteins-converting enzyme 1; Short=FACE-1; AltName: Full=Prenyl protein-specific endoprotease 1; AltName: Full=Zinc metalloproteinase Ste24 homolog;"]
[1027,"'CDKN1B'",343,319,396,352.666666666667,"05226///Gastric cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing's syndrome+++05206///MicroRNAs in cancer+++04066///HIF-1 signaling pathway+++05222///Small cell lung cancer+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++04012///ErbB signaling pathway+++05220///Chronic myeloid leukemia+++05169///Epstein-Barr virus infection+++05215///Prostate cancer+++05161///Hepatitis B+++04110///Cell cycle+++05162///Measles+++05203///Viral carcinogenesis","H00024///Prostate cancer+++H00018///Gastric cancer+++H01431///Cushing's syndrome+++H01102///Pituitary adenomas+++H00247///Multiple endocrine neoplasia syndrome (MEN)",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032991///protein-containing complex+++GO:0005768///endosome","GO:0051087///chaperone binding+++GO:0019903///protein phosphatase binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005072///transforming growth factor beta receptor, cytoplasmic mediator activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0044877///protein-containing complex binding","GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0051271///negative regulation of cellular component movement+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0043434///response to peptide hormone+++GO:0046686///response to cadmium ion+++GO:0009749///response to glucose+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0048839///inner ear development+++GO:0033673///negative regulation of kinase activity+++GO:0071285///cellular response to lithium ion+++GO:0045930///negative regulation of mitotic cell cycle+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042326///negative regulation of phosphorylation+++GO:0071236///cellular response to antibiotic+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007049///cell cycle+++GO:0014070///response to organic cyclic compound+++GO:0008219///cell death+++GO:0010942///positive regulation of cell death+++GO:0001666///response to hypoxia+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0008284///positive regulation of cell proliferation+++GO:0001890///placenta development+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0006813///potassium ion transport+++GO:0042493///response to drug+++GO:0045786///negative regulation of cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0031116///positive regulation of microtubule polymerization+++GO:0043200///response to amino acid+++GO:0071407///cellular response to organic cyclic compound+++GO:0007096///regulation of exit from mitosis+++GO:0042127///regulation of cell proliferation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest+++GO:0007507///heart development+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0007219///Notch signaling pathway+++GO:0007605///sensory perception of sound+++GO:0071850///mitotic cell cycle arrest+++GO:0045732///positive regulation of protein catabolic process+++GO:0032355///response to estradiol","cyclin dependent kinase inhibitor 1B","[CDN1B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1B; AltName: Full=Cyclin-dependent kinase inhibitor p27 {ECO:0000303|PubMed:28666995}; AltName: Full=p27Kip1 {ECO:0000303|PubMed:8033212};+++[A7KMP4_HUMAN|Unreviewed]SubName: Full=Truncated cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:ABS17636.1};+++[E7ES52_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000379629};+++[H7C2T1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000407597}; Flags: Fragment;+++[Q6I9V6_HUMAN|Unreviewed]SubName: Full=CDKN1B protein {ECO:0000313|EMBL:CAG33680.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:BAG70105.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B (P27, Kip1), isoform CRA_a {ECO:0000313|EMBL:EAW96275.1}; SubName: Full=cDNA, FLJ92816, Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1)(CDKN1B), mRNA {ECO:0000313|EMBL:BAG35368.1};+++[Q708J1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:CAE82383.1}; Flags: Fragment;"]
[10270,"'AKAP8'",416,276,312,334.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001939///female pronucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000793///condensed chromosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0046872///metal ion binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051059///NF-kappaB binding+++GO:0003723///RNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0042826///histone deacetylase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0002376///immune system process+++GO:0000278///mitotic cell cycle+++GO:0031065///positive regulation of histone deacetylation+++GO:0044839///cell cycle G2/M phase transition+++GO:0033127///regulation of histone phosphorylation+++GO:0007165///signal transduction+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0007076///mitotic chromosome condensation+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0015031///protein transport+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response","A-kinase anchoring protein 8","[AKAP8_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 8; Short=AKAP-8; AltName: Full=A-kinase anchor protein 95 kDa; Short=AKAP 95;+++[M0QX51_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000468902};+++[M0QYL4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000469908}; Flags: Fragment;+++[Q8NE02_HUMAN|Unreviewed]SubName: Full=AKAP8 protein {ECO:0000313|EMBL:AAH37270.1};"]
[10272,"'FSTL3'",14011,15507,13752,14423.3333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0030141///secretory granule+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0044306///neuron projection terminus+++GO:0005576///extracellular region","GO:0001968///fibronectin binding+++GO:0048185///activin binding+++GO:0005515///protein binding","GO:0030325///adrenal gland development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0044267///cellular protein metabolic process+++GO:0030324///lung development+++GO:0007283///spermatogenesis+++GO:0001822///kidney development+++GO:0043687///post-translational protein modification+++GO:0001503///ossification+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0008584///male gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0071248///cellular response to metal ion+++GO:0090101///negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045671///negative regulation of osteoclast differentiation","follistatin like 3","[FSTL3_HUMAN|Reviewed]RecName: Full=Follistatin-related protein 3; AltName: Full=Follistatin-like protein 3; AltName: Full=Follistatin-related gene protein; Flags: Precursor;+++[A0A024R1Y8_HUMAN|Unreviewed]SubName: Full=Follistatin-like 3 (Secreted glycoprotein), isoform CRA_a {ECO:0000313|EMBL:EAW61166.1};+++[A0A087WTD3_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000477770}; Flags: Fragment;+++[A0A087X1Q2_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000484376}; Flags: Fragment;+++[K7EM71_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000466383};"]
[102723360,"'LOC102723360'",25.18,37.51,22.74,28.4766666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding","GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression","uncharacterized LOC102723360","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102723475,"'KCNE1B'",29.5,0,26.68,18.7266666666667,{"$nulls":4},"GO:0008076///voltage-gated potassium channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005251///delayed rectifier potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding","GO:0006811///ion transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0097623///potassium ion export across plasma membrane+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086011///membrane repolarization during action potential+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport","potassium voltage-gated channel subfamily E regulatory subunit 1B","[KCE1B_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000305};+++[A0A087WU88_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000478461};+++[A0A087WWU3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000480511}; Flags: Fragment;"]
[102723502,"'LOC102723502'",6,7,5,6,{"$nulls":7},"POTE ankyrin domain family member B-like","[A0A0G2JMU2_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000479963};+++[A0A0G2JQB7_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000485729};"]
[102723534,"'LOC102723534'",8,9,10,9,"04120///Ubiquitin mediated proteolysis","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0032183///SUMO binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0007283///spermatogenesis+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006886///intracellular protein transport","E3 ubiquitin-protein ligase HERC2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[102723553,"'SMIM11B'",41.26,198.08,183.37,140.903333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"small integral membrane protein 11B","[SI11A_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11A {ECO:0000312|HGNC:HGNC:1293};+++[SI11B_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11B {ECO:0000312|HGNC:HGNC:51846};"]
[102723555,"'SPDYE16'",0,1,0.4,0.466666666666667,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E16","[SPD16_HUMAN|Reviewed]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[A0A0J9YVZ0_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487736};+++[A0A0J9YW45_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487806};+++[A0A0J9YWM7_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488034};+++[A0A0J9YYB4_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488772};+++[A0A0J9YYF2_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488825};"]
[102723623,"'LOC102723623'",0,0.61,0,0.203333333333333,{"$nulls":7},"golgin subfamily A member 6-like protein 6","[GG6L1_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 1;+++[GG6L2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 2;+++[GG6L6_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 6;+++[GG6L7_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 7 {ECO:0000305};+++[GG6LV_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};"]
[102723722,"'LOC102723722'",5.35,0,3.56,2.97,"01522///Endocrine resistance+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse","H01171///Poor drug metabolism (PM)",null,"R09421///4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP++++R08343///Citalopram <=> Demethylcitalopram+++R08345///Demethylcitalopram <=> Didemethylcitalopram+++R08344///Citalopram <=> Citalopram N-oxide+++R03697///Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen+++R08270///N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O+++R08267///Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O","GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005783///endoplasmic reticulum","GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0005506///iron ion binding+++GO:0004497///monooxygenase activity+++GO:0046872///metal ion binding+++GO:0008144///drug binding+++GO:0043023///ribosomal large subunit binding+++GO:0016491///oxidoreductase activity+++GO:0016887///ATPase activity+++GO:0008395///steroid hydroxylase activity+++GO:0005524///ATP binding+++GO:0043022///ribosome binding+++GO:0070330///aromatase activity+++GO:0005525///GTP binding+++GO:0020037///heme binding","GO:0090350///negative regulation of cellular organofluorine metabolic process+++GO:0017144///drug metabolic process+++GO:0016098///monoterpenoid metabolic process+++GO:0042737///drug catabolic process+++GO:0046034///ATP metabolic process+++GO:0051100///negative regulation of binding+++GO:0009820///alkaloid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0009804///coumarin metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0046483///heterocycle metabolic process+++GO:0033076///isoquinoline alkaloid metabolic process+++GO:0070989///oxidative demethylation+++GO:0009822///alkaloid catabolic process+++GO:0008202///steroid metabolic process+++GO:0042759///long-chain fatty acid biosynthetic process","uncharacterized LOC102723722","[CP2D6_HUMAN|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000269|PubMed:21576599}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000305|PubMed:21576599}; AltName: Full=Cytochrome P450-DB1; AltName: Full=Debrisoquine 4-hydroxylase;+++[CP2D6_PANPA|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D6_PANTR|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D7_HUMAN|diamond]RecName: Full=Putative cytochrome P450 2D7 {ECO:0000305}; EC=1.14.14.1 {ECO:0000269|PubMed:15051713};+++[CP2DH_MACFA|diamond]RecName: Full=Cytochrome P450 2D17; EC=1.14.14.1; AltName: Full=CYPIID17;+++[OLA1_BOVIN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_HUMAN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=DNA damage-regulated overexpressed in cancer 45; Short=DOC45; AltName: Full=GTP-binding protein 9;+++[OLA1_MOUSE|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=GTP-binding protein 9;+++[OLA1_PONAB|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_RAT|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};"]
[102723728,"'LOC102723728'",1628.31,3028.92,2055.69,2237.64,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding",null,"nodal modulator 3-like","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;"]
[102723750,"'LOC102723750'",0,2,4,2,{"$nulls":7},"uncharacterized LOC102723750","[K7DZX1_MONDO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000039072};+++[K7FQE9_PELSI|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000010259};"]
[102723849,"'SPDYE17'",0,0,2,0.666666666666667,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E17","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE2_HUMAN|diamond]RecName: Full=Speedy protein E2;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPE2B_HUMAN|diamond]RecName: Full=Speedy protein E2B;"]
[102723859,"'TBC1D3E'",88.54,81.74,66.53,78.9366666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3E","[TBC3E_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3E {ECO:0000312|HGNC:HGNC:27071};"]
[102723996,"'LOC102723996'",52.44,36.34,33.84,40.8733333333333,"04672///Intestinal immune network for IgA production+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0009986///cell surface+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding+++GO:0005102///signaling receptor binding","GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0042102///positive regulation of T cell proliferation+++GO:0031295///T cell costimulation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0042130///negative regulation of T cell proliferation+++GO:0006955///immune response","ICOS ligand","[ICOSL_HUMAN|Reviewed]RecName: Full=ICOS ligand; AltName: Full=B7 homolog 2; Short=B7-H2; AltName: Full=B7-like protein Gl50; AltName: Full=B7-related protein 1; Short=B7RP-1; AltName: CD_antigen=CD275; Flags: Precursor;+++[A0A087X1L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000484302};+++[A0A096LPE5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485557};+++[A0N0L8_HUMAN|Unreviewed]SubName: Full=Inducible T-cell co-stimulator ligand {ECO:0000313|EMBL:ABK41909.1}; SubName: Full=Inducible T-cell co-stimulator ligand, isoform CRA_c {ECO:0000313|EMBL:EAX09448.1}; SubName: Full=cDNA FLJ77643, highly similar to Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAF82881.1}; SubName: Full=cDNA, FLJ95137, Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAG36999.1};"]
[102724023,"'GATD3B'",288.96,217.08,287.57,264.536666666667,{"$nulls":4},"GO:0005739///mitochondrion",null,null,"glutamine amidotransferase like class 1 domain containing 3B","[GAL3B_HUMAN|Reviewed]RecName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial; AltName: Full=Keio novel protein-I {ECO:0000303|PubMed:8753807}; Short=KNP-I {ECO:0000303|PubMed:8753807}; AltName: Full=Protein GT335 {ECO:0000303|PubMed:8975701}; AltName: Full=Protein HES1 {ECO:0000303|PubMed:9150728}; Flags: Precursor;+++[A0A096LNH5_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000483086};+++[A0A096LNJ1_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485058}; Flags: Fragment;+++[A0A096LP12_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000374340}; SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485335}; Flags: Fragment;+++[A0A096LP57_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485404};+++[A0A096LP73_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485439}; Flags: Fragment;+++[A0A0B4J2H4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485300};"]
[102724135,"'LOC102724135'",28.63,16.44,30.24,25.1033333333333,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0004691///cAMP-dependent protein kinase activity","GO:0035023///regulation of Rho protein signal transduction","uncharacterized LOC102724135","[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOG8S_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8S {ECO:0000305};"]
[102724151,"'LOC102724151'",0,1,0,0.333333333333333,{"$nulls":7},"putative POM121-like protein 1","[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[102724159,"'LOC102724159'",136.76,124.32,81.04,114.04,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0032040///small-subunit processome","GO:0030515///snoRNA binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","periodic tryptophan protein 2 homolog","[PWP2_HUMAN|Reviewed]RecName: Full=Periodic tryptophan protein 2 homolog;+++[A0A0B4J2E5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000482107};+++[A0A0J9YX21_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000488213}; Flags: Fragment;"]
[102724197,"'LOC102724197'",1,4.03,3.01,2.68,"01100///Metabolic pathways+++00460///Cyanoamino acid metabolism+++00430///Taurine and hypotaurine metabolism+++00590///Arachidonic acid metabolism+++00480///Glutathione metabolism",null,null,"R09875///leukotriene-C4 hydrolase Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate+++R01687///(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase (5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine+++R00494///glutathione gamma-glutamylaminopeptidase Glutathione + H2O <=> Cys-Gly + L-Glutamate+++R03970///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase 3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O+++R03971///gamma-glutamyl-beta-aminopropiononitrile amidohydrolase 3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O+++R01262///glutathione:L-amino-acid 5-glutamyltransferase Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid+++R03916///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate","GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0036374///glutathione hydrolase activity+++GO:0000048///peptidyltransferase activity","GO:0006749///glutathione metabolic process+++GO:0019344///cysteine biosynthetic process+++GO:0031638///zymogen activation+++GO:0006751///glutathione catabolic process+++GO:0002682///regulation of immune system process+++GO:0006520///cellular amino acid metabolic process+++GO:0006412///translation+++GO:0031179///peptide modification+++GO:1901750///leukotriene D4 biosynthetic process+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0050727///regulation of inflammatory response+++GO:0032355///response to estradiol+++GO:0034612///response to tumor necrosis factor+++GO:0032496///response to lipopolysaccharide+++GO:0006536///glutamate metabolic process","inactive glutathione hydrolase 2","[GGT2_HUMAN|Reviewed]RecName: Full=Inactive glutathione hydrolase 2; AltName: Full=Gamma-glutamyltransferase 2; AltName: Full=Inactive gamma-glutamyltranspeptidase 2; Short=GGT 2; Flags: Precursor;+++[B5MCK8_HUMAN|Unreviewed]SubName: Full=Inactive glutathione hydrolase 2 {ECO:0000313|Ensembl:ENSP00000385601};"]
[102724200,"'LOC102724200'",23.17,9.72,16.47,16.4533333333333,{"$nulls":4},"GO:1990071///TRAPPII protein complex+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0034498///early endosome to Golgi transport","trafficking protein particle complex subunit 10-like","[A0A096LPH7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485615}; Flags: Fragment;"]
[102724219,"'LOC102724219'",66.74,117.58,85.04,89.7866666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation","uncharacterized LOC102724219","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724250,"'LOC102724250'",315.18,286.51,344.57,315.42,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"neuroblastoma breakpoint family member 1","[NBPF1_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 1;+++[NBPF8_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 8;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFA_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 10;+++[NBPFB_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000305}; AltName: Full=Neuroblastoma breakpoint family member 24 {ECO:0000312|HGNC:HGNC:31993};+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFJ_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};"]
[102724279,"'LINC01835'",2,2,1,1.66666666666667,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"long intergenic non-protein coding RNA 1835","[CLC4G_HUMAN|diamond]RecName: Full=C-type lectin domain family 4 member G; AltName: Full=Liver and lymph node sinusoidal endothelial cell C-type lectin {ECO:0000303|PubMed:14711836}; Short=LSECtin {ECO:0000303|PubMed:14711836};+++[COL12_CHICK|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin-3; Short=CL-3; Short=cCL-3;+++[COL12_HUMAN|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; Short=hCL-P1; AltName: Full=Nurse cell scavenger receptor 2; AltName: Full=Scavenger receptor class A member 4; AltName: Full=Scavenger receptor with C-type lectin;+++[COL12_MOUSE|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; AltName: Full=Scavenger receptor with C-type lectin;+++[COL12_RAT|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; AltName: Full=Nurse cell scavenger receptor 2;"]
[102724378,"'LOC102724378'",6,5,5,5.33333333333333,{"$nulls":7},"uncharacterized LOC102724378"]
[102724398,"'CH507-42P11.6'",1,0,0,0.333333333333333,{"$nulls":7},"uncharacterized CH507-42P11.6","[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[102724428,"'SIK1B'",6432,5952,5163.95,5849.31666666667,"04922///Glucagon signaling pathway","H00606///Early infantile epileptic encephalopathy+++H01819///Early myoclonic encephalopathy",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0032870///cellular response to hormone stimulus","salt inducible kinase 1B (putative)","[SIK1B_HUMAN|Reviewed]RecName: Full=Probable serine/threonine-protein kinase SIK1B {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:P57059, ECO:0000255|PROSITE-ProRule:PRU00159}; AltName: Full=Salt-inducible kinase 1B {ECO:0000305};+++[SIK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase SIK1; EC=2.7.11.1 {ECO:0000269|PubMed:14976552, ECO:0000269|PubMed:18348280}; AltName: Full=Salt-inducible kinase 1; Short=SIK-1; AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 1; Short=Serine/threonine-protein kinase SNF1LK;"]
[102724474,"'LOC102724474'",14,10,15,13,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0031233///intrinsic component of external side of plasma membrane","GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0051897///positive regulation of protein kinase B signaling+++GO:0030335///positive regulation of cell migration+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007596///blood coagulation+++GO:0007598///blood coagulation, extrinsic pathway","WAS/WASL-interacting protein family member 2-like","[FA10_BOVIN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_HUMAN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; AltName: Full=Stuart-Prower factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_MOUSE|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RABIT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RAT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;"]
[102724488,"'LOC102724488'",59.81,24.87,29.01,37.8966666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0019905///syntaxin binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding+++GO:0030276///clathrin binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0006906///vesicle fusion+++GO:0017158///regulation of calcium ion-dependent exocytosis","synaptotagmin-15","[SYT15_HUMAN|Reviewed]RecName: Full=Synaptotagmin-15; AltName: Full=Chr10Syt; AltName: Full=Synaptotagmin XV; Short=SytXV;+++[A0A096LNH4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000478933}; Flags: Fragment;+++[X6R8R1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-15 {ECO:0000313|Ensembl:ENSP00000363443};"]
[102724560,"'CBSL'",209.59,282.14,218.86,236.863333333333,"01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00270///Cysteine and methionine metabolism+++00260///Glycine, serine and threonine metabolism+++01230///Biosynthesis of amino acids","H00183///Homocystinuria","M00035///Methionine degradation+++M00338///Cysteine biosynthesis, homocysteine + serine => cysteine","R01290///L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)   L-Serine + L-Homocysteine <=> L-Cystathionine + H2O+++R04942///L-Serine hydro-lyase (adding homocysteine)   L-Serine + Selenohomocysteine <=> L-Selenocystathionine + H2O+++R00891///L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)   L-Serine + Hydrogen sulfide <=> L-Cysteine + H2O","GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016829///lyase activity+++GO:0004122///cystathionine beta-synthase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0004124///cysteine synthase activity+++GO:0020037///heme binding","GO:0008652///cellular amino acid biosynthetic process+++GO:0019344///cysteine biosynthetic process+++GO:0006535///cysteine biosynthetic process from serine+++GO:0019346///transsulfuration+++GO:0019343///cysteine biosynthetic process via cystathionine+++GO:0070814///hydrogen sulfide biosynthetic process+++GO:0050667///homocysteine metabolic process","cystathionine-beta-synthase like","[CBS_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase {ECO:0000305}; EC=4.2.1.22 {ECO:0000269|PubMed:20506325, ECO:0000269|PubMed:23974653, ECO:0000269|PubMed:23981774, ECO:0000269|PubMed:25044645}; AltName: Full=Beta-thionase; AltName: Full=Serine sulfhydrase;+++[CBSL_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase-like protein {ECO:0000305}; EC=4.2.1.22 {ECO:0000250|UniProtKB:P35520}; AltName: Full=Beta-thionase {ECO:0000250|UniProtKB:P35520}; AltName: Full=Serine sulfhydrase {ECO:0000250|UniProtKB:P35520};"]
[102724594,"'U2AF1L5'",32.8,0,97.41,43.4033333333333,"05131///Shigellosis+++03040///Spliceosome","H01481///Myelodysplastic syndrome (MDS)",null,null,"GO:0089701///U2AF+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0046872///metal ion binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0003723///RNA binding+++GO:0050733///RS domain binding+++GO:0003676///nucleic acid binding","GO:0000398///mRNA splicing, via spliceosome","U2 small nuclear RNA auxiliary factor 1 like 5","[U2AF1_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit; AltName: Full=U2 auxiliary factor 35 kDa subunit; AltName: Full=U2 small nuclear RNA auxiliary factor 1; AltName: Full=U2 snRNP auxiliary factor small subunit;+++[U2AF5_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000305}; AltName: Full=U2 small nuclear RNA auxiliary factor 1-like protein 5 {ECO:0000312|HGNC:HGNC:51830};+++[A0A1B0GW87_HUMAN|Unreviewed]SubName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000313|Ensembl:ENSP00000490825};"]
[102724642,"'LOC102724642'",0,3.5,0,1.16666666666667,"04111///Cell cycle - yeast+++04120///Ubiquitin mediated proteolysis+++04110///Cell cycle+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex+++GO:0005634///nucleus",null,"GO:0007049///cell cycle+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0051301///cell division","anaphase-promoting complex subunit 1-like","[APC1_CAEEL|diamond]RecName: Full=Anaphase-promoting complex subunit 1 {ECO:0000250|UniProtKB:Q9H1A4}; Short=APC1 {ECO:0000250|UniProtKB:Q9H1A4}; AltName: Full=Metaphase-to-anaphase transition protein 2 {ECO:0000312|WormBase:W10C6.1};+++[APC1_DICDI|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1;+++[APC1_HUMAN|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1; AltName: Full=Cyclosome subunit 1; AltName: Full=Mitotic checkpoint regulator; AltName: Full=Testis-specific gene 24 protein;+++[APC1_MOUSE|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1; AltName: Full=Cyclosome subunit 1; AltName: Full=Mitotic checkpoint regulator; AltName: Full=Testis-specific gene 24 protein;"]
[102724652,"'CRYAA2'",1,1,6,2.66666666666667,"04141///Protein processing in endoplasmic reticulum","H01202///Cataract",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050896///response to stimulus+++GO:0051260///protein homooligomerization+++GO:0032387///negative regulation of intracellular transport+++GO:0042026///protein refolding+++GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0007601///visual perception","crystallin alpha A2","[CRYA2_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A2 chain {ECO:0000305}; Contains: RecName: Full=Alpha-crystallin A2(1-172); Contains: RecName: Full=Alpha-crystallin A2(1-168); Contains: RecName: Full=Alpha-crystallin A2(1-162);+++[CRYAA_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A chain; AltName: Full=Heat shock protein beta-4; Short=HspB4; Contains: RecName: Full=Alpha-crystallin A(1-172); Contains: RecName: Full=Alpha-crystallin A(1-168); Contains: RecName: Full=Alpha-crystallin A(1-162);+++[A0A096LPJ9_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A2 chain {ECO:0000313|Ensembl:ENSP00000485653};+++[A0A140G952_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63592.1}; Flags: Fragment;+++[A0A140G954_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63594.1}; Flags: Fragment;+++[A0A140G955_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63595.1}; Flags: Fragment;+++[E7EWH7_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A chain {ECO:0000313|Ensembl:ENSP00000381201};+++[Q71V83_HUMAN|Unreviewed]SubName: Full=Alpha-A-crystallin {ECO:0000313|EMBL:AAB99912.1}; Flags: Fragment;"]
[102724751,"'LOC102724751'",62.17,74.35,72.34,69.62,"05200///Pathways in cancer+++05220///Chronic myeloid leukemia",{"$nulls":3},"GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0099092///postsynaptic density, intracellular component+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane","GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0050885///neuromuscular process controlling balance+++GO:0035023///regulation of Rho protein signal transduction+++GO:0071222///cellular response to lipopolysaccharide+++GO:0043314///negative regulation of neutrophil degranulation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050804///modulation of chemical synaptic transmission+++GO:0046777///protein autophosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0060268///negative regulation of respiratory burst+++GO:0002692///negative regulation of cellular extravasation+++GO:0065002///intracellular protein transmembrane transport+++GO:0050728///negative regulation of inflammatory response+++GO:0060313///negative regulation of blood vessel remodeling+++GO:0043547///positive regulation of GTPase activity+++GO:0050766///positive regulation of phagocytosis+++GO:0006468///protein phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0060216///definitive hemopoiesis+++GO:0051726///regulation of cell cycle+++GO:0043114///regulation of vascular permeability+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:0035556///intracellular signal transduction+++GO:0003014///renal system process+++GO:0048872///homeostasis of number of cells+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007420///brain development+++GO:0051171///regulation of nitrogen compound metabolic process","breakpoint cluster region protein-like","[ABR_BOVIN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_HUMAN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_MOUSE|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_XENTR|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[BCR_HUMAN|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1; AltName: Full=Renal carcinoma antigen NY-REN-26;+++[BCR_MOUSE|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1;"]
[102724770,"'LOC102724770'",158.01,177.35,242.08,192.48,"00330///Arginine and proline metabolism+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0031012///extracellular matrix+++GO:0005634///nucleus","GO:0004657///proline dehydrogenase activity","GO:0007155///cell adhesion+++GO:0009887///animal organ morphogenesis","protein DGCR6","[DGCR6_HUMAN|Reviewed]RecName: Full=Protein DGCR6; AltName: Full=DiGeorge syndrome critical region 6;+++[X5D7D2_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region 6 isoform D {ECO:0000313|EMBL:AHW56460.1}; Flags: Fragment;"]
[102724788,"'LOC102724788'",1045,1027,2067,1379.66666666667,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00330///Arginine and proline metabolism","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase   L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix","GO:0004657///proline dehydrogenase activity+++GO:0071949///FAD binding","GO:0019470///4-hydroxyproline catabolic process+++GO:0010133///proline catabolic process to glutamate+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0006562///proline catabolic process+++GO:0010942///positive regulation of cell death+++GO:0006560///proline metabolic process","proline dehydrogenase 1, mitochondrial","[PROD_BOVIN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000250|UniProtKB:O43272}; EC=1.5.5.2; AltName: Full=Proline oxidase {ECO:0000250|UniProtKB:O43272}; Flags: Precursor;+++[PROD_CAEEL|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;+++[PROD_DROME|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; AltName: Full=Protein sluggish-A; Flags: Precursor;+++[PROD_HUMAN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000305}; EC=1.5.5.2 {ECO:0000269|PubMed:15662599}; AltName: Full=Proline oxidase; AltName: Full=Proline oxidase 2; AltName: Full=p53-induced gene 6 protein; Flags: Precursor;+++[PROD_MOUSE|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;"]
[102724813,"'LOC102724813'",15,16,10,13.6666666666667,null,"H00591///Facioscapulohumeral muscular dystrophy (FSHD)",null,null,"GO:0015030///Cajal body+++GO:0005730///nucleolus+++GO:0030018///Z disc+++GO:0071013///catalytic step 2 spliceosome+++GO:0055120///striated muscle dense body","GO:0051015///actin filament binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006364///rRNA processing+++GO:0007517///muscle organ development","protein FRG1B","[FRG1_DROME|diamond]RecName: Full=Protein FRG1 homolog;+++[FRG1_HUMAN|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_MOUSE|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_TAKRU|diamond]RecName: Full=Protein FRG1;+++[FRG1_XENLA|diamond]RecName: Full=Protein FRG1 {ECO:0000250|UniProtKB:Q14331};"]
[102724843,"'LOC102724843'",314.93,166.69,373.52,285.046666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003677///DNA binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0006351///transcription, DNA-templated+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0043066///negative regulation of apoptotic process+++GO:0001933///negative regulation of protein phosphorylation","uncharacterized LOC102724843","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724951,"'LOC102724951'",80.4,99.09,72.72,84.07,{"$nulls":4},"GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005737///cytoplasm","GO:0004721///phosphoprotein phosphatase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0008284///positive regulation of cell proliferation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043066///negative regulation of apoptotic process","uncharacterized LOC102724951","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724957,"'LOC102724957'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC102724957","[M3YPU3_MUSPF|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMPUP00000013351};"]
[102724965,"'LOC102724965'",1,1,0,0.666666666666667,{"$nulls":7},"uncharacterized LOC102724965","[A0A2Y9SDV6_PHYCD|diamond]SubName: Full=uncharacterized protein LOC102995166 {ECO:0000313|RefSeq:XP_023974475.1};"]
[102724984,"'LOC102724984'",7.82,5.34,4.12,5.76,{"$nulls":3},"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0030170///pyridoxal phosphate binding+++GO:0045296///cadherin binding+++GO:0016831///carboxy-lyase activity","GO:0019752///carboxylic acid metabolic process","KIAA2013 pseudogene","[K2013_BOVIN|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_HUMAN|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_MOUSE|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_XENLA|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_XENTR|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[PDXD1_BOVIN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_HUMAN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_MOUSE|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_XENLA|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD2_HUMAN|diamond]RecName: Full=Putative pyridoxal-dependent decarboxylase domain-containing protein 2; EC=4.1.1.-; AltName: Full=pyridoxal-dependent decarboxylase domain-containing 2 pseudogene;"]
[102724985,"'LOC102724985'",923.65,852.22,716.53,830.8,null,"H00542///Polycystic kidney disease+++H01728///Potter syndrome",null,"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0016328///lateral plasma membrane+++GO:0005654///nucleoplasm+++GO:0005929///cilium+++GO:0002133///polycystin complex+++GO:0016323///basolateral plasma membrane+++GO:0031514///motile cilium+++GO:0005887///integral component of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0060170///ciliary membrane+++GO:0030660///Golgi-associated vesicle membrane","GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0005262///calcium channel activity+++GO:0001042///RNA polymerase I core binding+++GO:0045296///cadherin binding+++GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0016831///carboxy-lyase activity+++GO:0044325///ion channel binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding","GO:0042254///ribosome biogenesis+++GO:0008344///adult locomotory behavior+++GO:0030010///establishment of cell polarity+++GO:0008283///cell proliferation+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0072177///mesonephric duct development+++GO:0007507///heart development+++GO:0021510///spinal cord development+++GO:0030155///regulation of cell adhesion+++GO:0006611///protein export from nucleus+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0021915///neural tube development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0072205///metanephric collecting duct development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043588///skin development+++GO:0048565///digestive tract development+++GO:0072164///mesonephric tubule development+++GO:0060236///regulation of mitotic spindle organization+++GO:0036303///lymph vessel morphogenesis+++GO:0001889///liver development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001502///cartilage condensation+++GO:0010976///positive regulation of neuron projection development+++GO:0051216///cartilage development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009653///anatomical structure morphogenesis+++GO:0034405///response to fluid shear stress+++GO:0007613///memory+++GO:0072237///metanephric proximal tubule development+++GO:0007160///cell-matrix adhesion+++GO:0019752///carboxylic acid metabolic process+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0007050///cell cycle arrest+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0001701///in utero embryonic development+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0070588///calcium ion transmembrane transport+++GO:0007259///JAK-STAT cascade+++GO:0048872///homeostasis of number of cells+++GO:0060674///placenta blood vessel development+++GO:0001822///kidney development+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007028///cytoplasm organization+++GO:0072218///metanephric ascending thin limb development+++GO:0001892///embryonic placenta development+++GO:0007000///nucleolus organization+++GO:0048806///genitalia development+++GO:0050982///detection of mechanical stimulus+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0060428///lung epithelium development+++GO:2000142///regulation of DNA-templated transcription, initiation+++GO:0032092///positive regulation of protein binding+++GO:0007204///positive regulation of cytosolic calcium ion concentration","pyridoxal-dependent decarboxylase domain-containing protein 1","[PDXD1_HUMAN|Reviewed]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[H3BND4_HUMAN|Unreviewed]SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000454791};+++[Q86XE2_HUMAN|Unreviewed]SubName: Full=PDXDC1 protein {ECO:0000313|EMBL:AAH45554.2}; SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000437835};"]
[102724993,"'LOC102724993'",478.65,502.34,610.75,530.58,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0002133///polycystin complex+++GO:0060170///ciliary membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016323///basolateral plasma membrane+++GO:0009986///cell surface+++GO:0000139///Golgi membrane+++GO:0031514///motile cilium+++GO:0030660///Golgi-associated vesicle membrane+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm","GO:0019901///protein kinase binding+++GO:0030246///carbohydrate binding+++GO:0005262///calcium channel activity+++GO:0019904///protein domain specific binding+++GO:0044325///ion channel binding","GO:0036303///lymph vessel morphogenesis+++GO:0048565///digestive tract development+++GO:0043588///skin development+++GO:0001502///cartilage condensation+++GO:0032092///positive regulation of protein binding+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0072177///mesonephric duct development+++GO:0060674///placenta blood vessel development+++GO:0051216///cartilage development+++GO:0072218///metanephric ascending thin limb development+++GO:0060428///lung epithelium development+++GO:0072237///metanephric proximal tubule development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0007259///JAK-STAT cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0001701///in utero embryonic development+++GO:0072164///mesonephric tubule development+++GO:0030010///establishment of cell polarity+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0021915///neural tube development+++GO:0001892///embryonic placenta development+++GO:0048806///genitalia development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0015031///protein transport+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0021510///spinal cord development+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072205///metanephric collecting duct development+++GO:0060236///regulation of mitotic spindle organization+++GO:0034405///response to fluid shear stress+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0001822///kidney development+++GO:0007160///cell-matrix adhesion+++GO:0007507///heart development+++GO:0030155///regulation of cell adhesion+++GO:0050982///detection of mechanical stimulus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0001889///liver development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0007050///cell cycle arrest","nuclear pore complex-interacting protein family member A7-like","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;+++[NPIA1_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A1; AltName: Full=Nuclear pore complex-interacting protein; Short=NPIP;+++[NPIA2_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A2;+++[NPIA3_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A3;+++[NPIA5_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[NPIA7_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[PKD1_HUMAN|diamond]RecName: Full=Polycystin-1; Short=PC1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein; Flags: Precursor;+++[PKD1_MOUSE|diamond]RecName: Full=Polycystin-1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein homolog; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[102724994,"'LOC102724994'",0.5,0,0,0.166666666666667,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"POM121 membrane glycoprotein pseudogene","[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;"]
[102724995,"'LOC102724995'",0.5,0,0,0.166666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005764///lysosome","GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004566///beta-glucuronidase activity","GO:0007399///nervous system development+++GO:0001501///skeletal system development+++GO:0005975///carbohydrate metabolic process","POM121 membrane glycoprotein pseudogene","[BGLR_CANLF|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_CHLAE|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor; Fragment;+++[BGLR_FELCA|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_HUMAN|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; AltName: Full=Beta-G1; Flags: Precursor;+++[BGLR_PONAB|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[GUSP1_HUMAN|diamond]RecName: Full=Putative inactive beta-glucuronidase-like protein SMA3;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;"]
[102725009,"'LOC102725009'",51.04,37.97,38.96,42.6566666666667,{"$nulls":4},"GO:0005764///lysosome","GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0007399///nervous system development+++GO:0001501///skeletal system development","putative inactive beta-glucuronidase-like protein SMA3","[BGLR_CHLAE|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor; Fragment;+++[BGLR_FELCA|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_HUMAN|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; AltName: Full=Beta-G1; Flags: Precursor;+++[BGLR_PONAB|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[GUSP1_HUMAN|diamond]RecName: Full=Putative inactive beta-glucuronidase-like protein SMA3;"]
[10273,"'STUB1'",1681,1941,1720,1780.66666666667,"04141///Protein processing in endoplasmic reticulum+++04120///Ubiquitin mediated proteolysis","H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0000151///ubiquitin ligase complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0030018///Z disc+++GO:0101031///chaperone complex+++GO:0005829///cytosol+++GO:0042405///nuclear inclusion body+++GO:0031371///ubiquitin conjugating enzyme complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0031072///heat shock protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0048156///tau protein binding+++GO:0030674///protein binding, bridging+++GO:0004842///ubiquitin-protein transferase activity+++GO:0051087///chaperone binding+++GO:0042803///protein homodimerization activity+++GO:0051879///Hsp90 protein binding+++GO:0019899///enzyme binding+++GO:0046332///SMAD binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0051787///misfolded protein binding+++GO:0030911///TPR domain binding+++GO:0001664///G protein-coupled receptor binding+++GO:0030544///Hsp70 protein binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0019900///kinase binding","GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0061684///chaperone-mediated autophagy+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0051604///protein maturation+++GO:0032091///negative regulation of protein binding+++GO:0071456///cellular response to hypoxia+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0034605///cellular response to heat+++GO:0031398///positive regulation of protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031943///regulation of glucocorticoid metabolic process+++GO:0002931///response to ischemia+++GO:0006281///DNA repair+++GO:0038128///ERBB2 signaling pathway+++GO:0031647///regulation of protein stability+++GO:0030968///endoplasmic reticulum unfolded protein response","STIP1 homology and U-box containing protein 1","[CHIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:11557750, ECO:0000269|PubMed:15466472}; AltName: Full=Antigen NY-CO-7 {ECO:0000303|PubMed:9610721}; AltName: Full=CLL-associated antigen KW-8 {ECO:0000303|PubMed:12200376}; AltName: Full=Carboxy terminus of Hsp70-interacting protein {ECO:0000303|PubMed:10330192}; AltName: Full=RING-type E3 ubiquitin transferase CHIP {ECO:0000305}; AltName: Full=STIP1 homology and U box-containing protein 1 {ECO:0000312|HGNC:HGNC:11427};+++[H3BS86_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000456591}; Flags: Fragment;+++[H3BTA3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457090}; Flags: Fragment;+++[H3BUD0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457583}; Flags: Fragment;+++[V9GYH3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000476751}; Flags: Fragment;"]
[10274,"'STAG1'",317,205,220,247.333333333333,"04113///Meiosis - yeast+++04110///Cell cycle+++04111///Cell cycle - yeast","H00773///Autosomal dominant mental retardation",null,null,"GO:0016363///nuclear matrix+++GO:0097431///mitotic spindle pole+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000775///chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006351///transcription, DNA-templated+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1901673///regulation of mitotic spindle assembly+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division","stromal antigen 1","[STAG1_HUMAN|Reviewed]RecName: Full=Cohesin subunit SA-1; AltName: Full=SCC3 homolog 1; AltName: Full=Stromal antigen 1;+++[Q4LE48_HUMAN|Unreviewed]SubName: Full=STAG1 variant protein {ECO:0000313|EMBL:BAE06105.1}; Flags: Fragment;"]
[10276,"'NET1'",120,94,114,109.333333333333,"04540///Gap junction+++04210///Apoptosis+++04530///Tight junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H00268///Lissencephaly (LIS)+++H00058///Amyotrophic lateral sclerosis (ALS)+++H00271///Polymicrogyria",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0005200///structural constituent of cytoskeleton+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0017049///GTP-Rho binding+++GO:0003924///GTPase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005525///GTP binding","GO:0035023///regulation of Rho protein signal transduction+++GO:0051451///myoblast migration+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0070301///cellular response to hydrogen peroxide+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0007017///microtubule-based process+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0001558///regulation of cell growth","neuroepithelial cell transforming 1","[ARHG8_HUMAN|Reviewed]RecName: Full=Neuroepithelial cell-transforming gene 1 protein; AltName: Full=Proto-oncogene p65 Net1; AltName: Full=Rho guanine nucleotide exchange factor 8;+++[Q5SQI5_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW86446.1}; SubName: Full=cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 protein {ECO:0000313|EMBL:BAG61338.1};+++[Q5SQI7_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_a {ECO:0000313|EMBL:EAW86445.1}; SubName: Full=cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA {ECO:0000313|EMBL:BAG37941.1};"]
[10277,"'UBE4B'",2051,1677,1839,1855.66666666667,"04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0051117///ATPase binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0044257///cellular protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0051865///protein autoubiquitination+++GO:0034976///response to endoplasmic reticulum stress+++GO:0009411///response to UV+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0008626///granzyme-mediated apoptotic signaling pathway+++GO:0016567///protein ubiquitination+++GO:0006513///protein monoubiquitination+++GO:0031175///neuron projection development+++GO:0000209///protein polyubiquitination","ubiquitination factor E4B","[UBE4B_HUMAN|Reviewed]RecName: Full=Ubiquitin conjugation factor E4 B {ECO:0000305}; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q9ES00}; AltName: Full=Homozygously deleted in neuroblastoma 1 {ECO:0000312|EMBL:BAB40446.1}; AltName: Full=RING-type E3 ubiquitin transferase E4 B; AltName: Full=Ubiquitin fusion degradation protein 2 {ECO:0000312|EMBL:AAD02233.1};+++[B1AQ61_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000366358};+++[K7EP75_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000467258}; Flags: Fragment;+++[K7ERA7_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000468178}; Flags: Fragment;"]
[10278,"'EFS'",69,68,86,74.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0017124///SH3 domain binding","GO:0016477///cell migration+++GO:0035556///intracellular signal transduction+++GO:0090527///actin filament reorganization+++GO:0007155///cell adhesion","embryonal Fyn-associated substrate","[EFS_HUMAN|Reviewed]RecName: Full=Embryonal Fyn-associated substrate; Short=hEFS; AltName: Full=Cas scaffolding protein family member 3;"]
[10279,"'PRSS16'",31,27,32,30,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:0016020///membrane","GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis+++GO:0030163///protein catabolic process","serine protease 16","[TSSP_HUMAN|Reviewed]RecName: Full=Thymus-specific serine protease; EC=3.4.-.-; AltName: Full=Serine protease 16; Flags: Precursor;+++[B4DZV2_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000396589}; SubName: Full=cDNA FLJ52815, highly similar to Thymus-specific serine protease {ECO:0000313|EMBL:BAG64214.1};+++[C9JDN6_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419492};+++[F2Z2N5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000404349};+++[F8WBG5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418036};+++[F8WF25_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419437};+++[H0Y893_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418710}; Flags: Fragment;+++[H0Y8B9_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419538}; Flags: Fragment;"]
[1028,"'CDKN1C'",1750,1630,2674,2018,"04110///Cell cycle","H01772///Adrenal hypoplasia congenita+++H00713///Beckwith-Wiedemann syndrome+++H00033///Adrenal carcinoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity","GO:0071514///genetic imprinting+++GO:0001501///skeletal system development+++GO:0035264///multicellular organism growth+++GO:0001822///kidney development+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0007049///cell cycle+++GO:0060065///uterus development+++GO:0007096///regulation of exit from mitosis+++GO:0033673///negative regulation of kinase activity+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0007050///cell cycle arrest+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042326///negative regulation of phosphorylation+++GO:0030099///myeloid cell differentiation+++GO:0055123///digestive system development+++GO:0043010///camera-type eye development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007568///aging+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0016310///phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001890///placenta development+++GO:0030325///adrenal gland development+++GO:0060669///embryonic placenta morphogenesis+++GO:0042551///neuron maturation+++GO:0007346///regulation of mitotic cell cycle","cyclin dependent kinase inhibitor 1C","[CDN1C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1C; AltName: Full=Cyclin-dependent kinase inhibitor p57; AltName: Full=p57Kip2;+++[A0A0G2JH30_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000321019};+++[A0A0G2JPX0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000484462};+++[A0A2R8YFP9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000496631};+++[A6NK88_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000370101};+++[B2D1N3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C transcript variant 3 {ECO:0000313|EMBL:ACB69757.1};"]
[10280,"'SIGMAR1'",3780,4191,3831,3934,null,"H00856///Distal hereditary motor neuropathies (dHMN)+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0016021///integral component of membrane+++GO:0005640///nuclear outer membrane+++GO:0030426///growth cone+++GO:0014069///postsynaptic density+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005811///lipid droplet+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0004985///opioid receptor activity+++GO:0008144///drug binding","GO:0006869///lipid transport+++GO:0036474///cell death in response to hydrogen peroxide+++GO:0038003///opioid receptor signaling pathway+++GO:0070207///protein homotrimerization+++GO:0007399///nervous system development+++GO:0043523///regulation of neuron apoptotic process","sigma non-opioid intracellular receptor 1","[SGMR1_HUMAN|Reviewed]RecName: Full=Sigma non-opioid intracellular receptor 1; AltName: Full=Aging-associated gene 8 protein; AltName: Full=SR31747-binding protein; Short=SR-BP; AltName: Full=Sigma 1-type opioid receptor; Short=SIG-1R; Short=Sigma1-receptor; Short=Sigma1R; Short=hSigmaR1;+++[A2A3U5_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_d {ECO:0000313|EMBL:EAW58436.1}; SubName: Full=cDNA FLJ76396, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83781.1};+++[B4DR71_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57078, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61183.1};+++[Q5T1J1_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_c {ECO:0000313|EMBL:EAW58433.1}; SubName: Full=Sigma non-opioid intracellular receptor 1 {ECO:0000313|Ensembl:ENSP00000368170};"]
[102800317,"'TPTEP2-CSNK1E'",160.9,74.85,140.83,125.526666666667,"04068///FoxO signaling pathway+++04711///Circadian rhythm - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species+++04710///Circadian rhythm+++04310///Wnt signaling pathway+++04391///Hippo signaling pathway - fly+++04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042752///regulation of circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0008360///regulation of cell shape+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway+++GO:0006281///DNA repair+++GO:0007165///signal transduction+++GO:0032197///transposition, RNA-mediated+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0006468///protein phosphorylation+++GO:1903827///regulation of cellular protein localization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1905426///positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation+++GO:0006897///endocytosis+++GO:0060070///canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006310///DNA recombination+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle","TPTEP2-CSNK1E readthrough","[KC1E_HUMAN|Reviewed]RecName: Full=Casein kinase I isoform epsilon; Short=CKI-epsilon; Short=CKIe; EC=2.7.11.1;+++[B3KRV2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34950 fis, clone NT2RP7017284, highly similar to Casein kinase I isoform epsilon {ECO:0000313|EMBL:BAG52514.1};+++[Q5U045_HUMAN|Unreviewed]SubName: Full=Casein kinase 1 epsilon {ECO:0000313|EMBL:ABM64212.1}; SubName: Full=Casein kinase 1, epsilon {ECO:0000313|EMBL:AAV38634.1}; SubName: Full=HCG2014051, isoform CRA_a {ECO:0000313|EMBL:EAW60228.1};"]
[10282,"'BET1'",116,121,115,117.333333333333,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0030173///integral component of Golgi membrane","GO:0005515///protein binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","Bet1 golgi vesicular membrane trafficking protein","[BET1_HUMAN|Reviewed]RecName: Full=BET1 homolog; Short=hBET1; AltName: Full=Golgi vesicular membrane-trafficking protein p18;+++[C9JTT8_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000413063};+++[H7C1N3_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000401260}; Flags: Fragment;+++[Q53XK0_HUMAN|Unreviewed]SubName: Full=BET1 homolog (S. cerevisiae) {ECO:0000313|EMBL:AAP88855.1}; SubName: Full=BET1 homolog (S. cerevisiae), isoform CRA_d {ECO:0000313|EMBL:EAW76803.1}; SubName: Full=cDNA, FLJ94635, Homo sapiens BET1 homolog (S. cerevisiae) (BET1), mRNA {ECO:0000313|EMBL:BAG36696.1};+++[Q68DU7_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000350125};"]
[10283,"'CWC27'",317,274,264,285,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0071012///catalytic step 1 spliceosome","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding","GO:0000413///protein peptidyl-prolyl isomerization+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006457///protein folding","CWC27 spliceosome associated protein homolog","[CWC27_HUMAN|Reviewed]RecName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000305}; AltName: Full=Antigen NY-CO-10 {ECO:0000303|PubMed:9610721}; AltName: Full=Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog {ECO:0000305|PubMed:20676357}; Short=PPIase CWC27 {ECO:0000305|PubMed:20676357}; AltName: Full=Serologically defined colon cancer antigen 10;+++[D6REK3_HUMAN|Unreviewed]SubName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000313|Ensembl:ENSP00000426802};"]
[10284,"'SAP18'",1041,1081,1109,1077,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0000118///histone deacetylase complex+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0061574///ASAP complex","GO:0004407///histone deacetylase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity","GO:0008380///RNA splicing+++GO:0043065///positive regulation of apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0048025///negative regulation of mRNA splicing, via spliceosome","Sin3A associated protein 18","[SAP18_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP18; AltName: Full=18 kDa Sin3-associated polypeptide; AltName: Full=2HOR0202; AltName: Full=Cell growth-inhibiting gene 38 protein; AltName: Full=Sin3-associated polypeptide p18;+++[H7BZW6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000391846}; Flags: Fragment;+++[U3KPY7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475358}; Flags: Fragment;+++[U3KQ12_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475435}; Flags: Fragment;+++[X6RAL5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000371973};"]
[10285,"'SMNDC1'",248,164,208,206.666666666667,"03040///Spliceosome",{"$nulls":3},"GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0008380///RNA splicing+++GO:0006915///apoptotic process","survival motor neuron domain containing 1","[SPF30_HUMAN|Reviewed]RecName: Full=Survival of motor neuron-related-splicing factor 30; AltName: Full=30 kDa splicing factor SMNrp; AltName: Full=SMN-related protein; AltName: Full=Survival motor neuron domain-containing protein 1;"]
[10286,"'BCAS2'",394,392,341,375.666666666667,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005634///nucleus+++GO:0000974///Prp19 complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005813///centrosome+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005730///nucleolus","GO:0005515///protein binding","GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000375///RNA splicing, via transesterification reactions","BCAS2, pre-mRNA processing factor","[SPF27_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SPF27; AltName: Full=Breast carcinoma-amplified sequence 2; AltName: Full=DNA amplified in mammary carcinoma 1 protein; AltName: Full=Spliceosome-associated protein SPF 27;+++[B2R7W3_HUMAN|Unreviewed]SubName: Full=Breast carcinoma amplified sequence 2 {ECO:0000313|EMBL:BAG70059.1}; SubName: Full=Breast carcinoma amplified sequence 2, isoform CRA_a {ECO:0000313|EMBL:EAW56602.1}; SubName: Full=cDNA, FLJ93631, Homo sapiens breast carcinoma amplified sequence 2 (BCAS2), mRNA {ECO:0000313|EMBL:BAG35960.1};"]
[10287,"'RGS19'",199,195,129,174.333333333333,{"$nulls":4},"GO:0005903///brush border+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030136///clathrin-coated vesicle","GO:0001965///G-protein alpha-subunit binding+++GO:0005515///protein binding","GO:0007264///small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0045471///response to ethanol+++GO:0006914///autophagy","regulator of G protein signaling 19","[RGS19_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 19; Short=RGS19; AltName: Full=G-alpha-interacting protein; Short=GAIP;+++[B4DP94_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59828, highly similar to Regulator of G-protein signaling 19 {ECO:0000313|EMBL:BAG60506.1};+++[Q6I9S5_HUMAN|Unreviewed]SubName: Full=RGS19 protein {ECO:0000313|EMBL:CAG33711.1};+++[Q9H2T9_HUMAN|Unreviewed]SubName: Full=G alpha interacting protein {ECO:0000313|EMBL:AAG42352.1}; Flags: Fragment;"]
[10289,"'EIF1B'",414,481,473,456,"03013///RNA transport",{"$nulls":3},"GO:0005575///cellular_component+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0043024///ribosomal small subunit binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006446///regulation of translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation","eukaryotic translation initiation factor 1B","[EIF1B_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1b; Short=eIF1b; AltName: Full=Protein translation factor SUI1 homolog GC20;+++[Q6FG85_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1B, isoform CRA_a {ECO:0000313|EMBL:EAW64598.1}; SubName: Full=GC20 protein {ECO:0000313|EMBL:CAG47019.1}; SubName: Full=cDNA, FLJ92189, Homo sapiens translation factor sui1 homolog (GC20), mRNA {ECO:0000313|EMBL:BAG34863.1}; Flags: Fragment;"]
[1029,"'CDKN2A'",12607,13687,10812,12368.6666666667,"04934///Cushing's syndrome+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++01524///Platinum drug resistance+++05214///Glioma+++05223///Non-small cell lung cancer+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05163///Human cytomegalovirus infection+++05212///Pancreatic cancer+++04218///Cellular senescence+++05219///Bladder cancer+++04110///Cell cycle+++05166///HTLV-I infection+++01522///Endocrine resistance+++05218///Melanoma+++05200///Pathways in cancer","H01513///Retinoblastoma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00054///Nasopharyngeal cancer+++H01556///Meningioma+++H00015///Malignant pleural mesothelioma+++H00042///Glioma+++H00008///Burkitt lymphoma+++H00040///Squamous cell carcinoma+++H00009///Adult T-cell leukemia+++H00017///Esophageal cancer+++H00014///Non-small cell lung cancer+++H00025///Penile cancer+++H00004///Chronic myeloid leukemia (CML)+++H00016///Oral cancer+++H01509///Tonsillar cancer+++H01464///Mantle cell lymphoma+++H00055///Laryngeal cancer+++H00047///Gallbladder cancer+++H00048///Hepatocellular carcinoma+++H01508///Salivary gland cancer+++H00046///Cholangiocarcinoma+++H00409///Type II diabetes mellitus+++H00038///Melanoma+++H00022///Bladder cancer+++H00019///Pancreatic cancer",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035985///senescence-associated heterochromatin focus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0003723///RNA binding+++GO:0055105///ubiquitin-protein transferase inhibitor activity+++GO:0097718///disordered domain specific binding+++GO:0019901///protein kinase binding+++GO:0051059///NF-kappaB binding+++GO:1990948///ubiquitin ligase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0003677///DNA binding+++GO:0002039///p53 binding+++GO:0019789///SUMO transferase activity+++GO:0016301///kinase activity","GO:0050821///protein stabilization+++GO:0090399///replicative senescence+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0033235///positive regulation of protein sumoylation+++GO:0042326///negative regulation of phosphorylation+++GO:0000422///autophagy of mitochondrion+++GO:0046825///regulation of protein export from nucleus+++GO:0030889///negative regulation of B cell proliferation+++GO:0000209///protein polyubiquitination+++GO:2000435///negative regulation of protein neddylation+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0016925///protein sumoylation+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007265///Ras protein signal transduction+++GO:0007050///cell cycle arrest+++GO:0051882///mitochondrial depolarization+++GO:0071158///positive regulation of cell cycle arrest+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0031648///protein destabilization+++GO:0016310///phosphorylation+++GO:0008637///apoptotic mitochondrial changes+++GO:0048103///somatic stem cell division+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0090398///cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0030308///negative regulation of cell growth+++GO:1902510///regulation of apoptotic DNA fragmentation+++GO:0006469///negative regulation of protein kinase activity+++GO:0070534///protein K63-linked ubiquitination+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:1903051///negative regulation of proteolysis involved in cellular protein catabolic process+++GO:2000774///positive regulation of cellular senescence+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006915///apoptotic process+++GO:1990000///amyloid fibril formation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0031647///regulation of protein stability+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:2000111///positive regulation of macrophage apoptotic process+++GO:0006364///rRNA processing+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","cyclin dependent kinase inhibitor 2A","[ARF_HUMAN|Reviewed]RecName: Full=Tumor suppressor ARF {ECO:0000305}; AltName: Full=Alternative reading frame {ECO:0000303|PubMed:9724636}; Short=ARF {ECO:0000303|PubMed:9724636}; AltName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=p14ARF {ECO:0000303|PubMed:9724636};+++[CDN2A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=Cyclin-dependent kinase 4 inhibitor A; Short=CDK4I; AltName: Full=Multiple tumor suppressor 1; Short=MTS-1; AltName: Full=p16-INK4a; Short=p16-INK4; Short=p16INK4A;+++[A7LNE7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:ABS32187.1}; Flags: Fragment;+++[D1LYX3_HUMAN|Unreviewed]SubName: Full=Truncated tumor suppressor protein P16 {ECO:0000313|EMBL:ACY78326.1};+++[J3QRG6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000464202};+++[K7ENC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000466887};+++[K7ES20_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000468510};+++[K7PML8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AFN61600.1};+++[L8E941_HUMAN|Unreviewed]SubName: Full=Alternative protein CDKN2A {ECO:0000313|EMBL:CCQ43815.1};+++[Q208B5_HUMAN|Unreviewed]SubName: Full=p16 {ECO:0000313|EMBL:ABD72255.1}; Flags: Fragment;+++[Q2MJK0_HUMAN|Unreviewed]SubName: Full=p16 protein {ECO:0000313|EMBL:ABC50001.1}; Flags: Fragment;+++[Q5ZEY9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:CAH59950.1}; Flags: Fragment;+++[Q9UPB7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AAD02319.1}; Flags: Fragment;"]
[10290,"'SPEG'",2996,2995,2403,2798,null,"H00700///Centronuclear myopathy",null,null,"GO:0005634///nucleus","GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0072358///cardiovascular system development+++GO:0030154///cell differentiation+++GO:0016310///phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0042692///muscle cell differentiation+++GO:0007517///muscle organ development","SPEG complex locus","[SPEG_HUMAN|Reviewed]RecName: Full=Striated muscle preferentially expressed protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[B9ZVR7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000379926};+++[C9J8D8_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000410986}; Flags: Fragment;+++[C9JWU5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000393134}; Flags: Fragment;+++[F8WCA7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000406530};+++[G5E9J7_HUMAN|Unreviewed]SubName: Full=Aortic preferentially expressed gene 1, isoform CRA_i {ECO:0000313|EMBL:EAW70750.1}; SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000397514};+++[H0Y3W0_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000387344}; Flags: Fragment;+++[H7BZM6_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000390353}; Flags: Fragment;+++[H7C3Y5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000414549}; Flags: Fragment;"]
[10291,"'SF3A1'",3314,3101,3263,3226,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0005684///U2-type spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005686///U2 snRNP+++GO:0071004///U2-type prespliceosome+++GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000389///mRNA 3'-splice site recognition","splicing factor 3a subunit 1","[SF3A1_HUMAN|Reviewed]RecName: Full=Splicing factor 3A subunit 1; AltName: Full=SF3a120; AltName: Full=Spliceosome-associated protein 114; Short=SAP 114;+++[A0A024R1K8_HUMAN|Unreviewed]SubName: Full=Splicing factor 3a, subunit 1, 120kDa, isoform CRA_a {ECO:0000313|EMBL:EAW59879.1};+++[F8WB66_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000397267};+++[F8WC79_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000412715};+++[H7C1L2_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000400862}; Flags: Fragment;"]
[10293,"'TRAIP'",22,19,37,26,null,"H00992///Seckel syndrome",null,null,"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0016567///protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0008283///cell proliferation+++GO:0032688///negative regulation of interferon-beta production+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway","TRAF interacting protein","[TRAIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRAIP; EC=2.3.2.27; AltName: Full=RING finger protein 206; AltName: Full=RING-type E3 ubiquitin transferase TRAIP {ECO:0000305}; AltName: Full=TRAF-interacting protein;+++[E7EN91_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000418544}; Flags: Fragment;+++[E7ETV1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000420085};+++[E7EVC4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419556};+++[E7EW89_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419350}; Flags: Fragment;"]
[10294,"'DNAJA2'",694,649,610,651,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0001671///ATPase activator activity+++GO:0031072///heat shock protein binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006457///protein folding+++GO:0042026///protein refolding+++GO:0008284///positive regulation of cell proliferation+++GO:0009408///response to heat+++GO:0032781///positive regulation of ATPase activity","DnaJ heat shock protein family (Hsp40) member A2","[DNJA2_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily A member 2; AltName: Full=Cell cycle progression restoration gene 3 protein; AltName: Full=Dnj3; Short=Dj3; AltName: Full=HIRA-interacting protein 4; AltName: Full=Renal carcinoma antigen NY-REN-14; Flags: Precursor;+++[A0A024R6S1_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily A, member 2, isoform CRA_a {ECO:0000313|EMBL:EAW82694.1};+++[A0A087WT48_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000477579}; Flags: Fragment;+++[I3L320_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000460104};"]
[10295,"'BCKDK'",1826,2079,2005,1970,null,"H02136///Branched-chain ketoacid dehydrogenase kinase deficiency",null,null,"GO:0005947///mitochondrial alpha-ketoglutarate dehydrogenase complex+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0047323///[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0009083///branched-chain amino acid catabolic process+++GO:0009063///cellular amino acid catabolic process","branched chain ketoacid dehydrogenase kinase","[BCKD_HUMAN|Reviewed]RecName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; EC=2.7.11.4; AltName: Full=Branched-chain alpha-ketoacid dehydrogenase kinase; Short=BCKD-kinase; Short=BCKDHKIN; Flags: Precursor;+++[A0A024QZA9_HUMAN|Unreviewed]SubName: Full=Branched chain ketoacid dehydrogenase kinase, isoform CRA_b {ECO:0000313|EMBL:EAW52162.1};+++[H3BNP3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000454947}; Flags: Fragment;+++[H3BQP2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000455866}; Flags: Fragment;+++[H3BS02_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456479};+++[H3BTL2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457226}; Flags: Fragment;+++[H3BUV3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457821}; Flags: Fragment;"]
[10296,"'MAEA'",1286,1290,1216,1264,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0034657///GID complex+++GO:0005826///actomyosin contractile ring+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix","GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0003779///actin binding","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045721///negative regulation of gluconeogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048821///erythrocyte development+++GO:0043249///erythrocyte maturation+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0048822///enucleate erythrocyte development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007155///cell adhesion","macrophage erythroblast attacher","[MAEA_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein transferase MAEA; EC=2.3.2.27 {ECO:0000269|PubMed:29911972}; AltName: Full=Cell proliferation-inducing gene 5 protein {ECO:0000303|Ref.1}; AltName: Full=Erythroblast macrophage protein {ECO:0000303|PubMed:9763581}; AltName: Full=Human lung cancer oncogene 10 protein; Short=HLC-10; AltName: Full=Macrophage erythroblast attacher; AltName: Full=P44EMLP {ECO:0000303|PubMed:17467196};+++[B3KRN7_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_c {ECO:0000313|EMBL:EAW82589.1}; SubName: Full=cDNA FLJ34632 fis, clone KIDNE2015660, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG52449.1};+++[B4DJP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54833, moderately similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG58910.1};+++[B4DQT1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000424436}; SubName: Full=cDNA FLJ53639, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61043.1};+++[B4DVN3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000426807}; SubName: Full=cDNA FLJ54556, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62745.1};+++[D3DVP1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_b {ECO:0000313|EMBL:EAW82591.1};+++[D3DVP3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_a {ECO:0000313|EMBL:EAW82588.1};+++[D3DVP6_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_d {ECO:0000313|EMBL:EAW82592.1};+++[D6R8Z3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422235};+++[D6RA86_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000423056};+++[D6RDW4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426966};+++[D6RE80_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426903}; Flags: Fragment;+++[D6REW7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000421644}; Flags: Fragment;+++[D6RIB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427512};+++[D6RID6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427460}; Flags: Fragment;+++[E7ESC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422215};"]
[10297,"'APC2'",618,558,1160,778.666666666667,"05224///Breast cancer+++04390///Hippo signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05213///Endometrial cancer+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04810///Regulation of actin cytoskeleton+++05206///MicroRNAs in cancer+++04310///Wnt signaling pathway+++05165///Human papillomavirus infection+++05166///HTLV-I infection+++04550///Signaling pathways regulating pluripotency of stem cells+++05210///Colorectal cancer+++05225///Hepatocellular carcinoma","H02049///Bilateral macronodular adrenal hyperplasia (BMAH)+++H00017///Esophageal cancer+++H00020///Colorectal cancer+++H00044///Cancer of the anal canal+++H01431///Cushing's syndrome+++H01667///Medulloblastoma+++H01025///Familial adenomatous polyposis+++H00018///Gastric cancer+++H00047///Gallbladder cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030496///midbody+++GO:0015630///microtubule cytoskeleton+++GO:0031258///lamellipodium membrane+++GO:0005884///actin filament+++GO:0045171///intercellular bridge+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0016342///catenin complex+++GO:0016020///membrane","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0008017///microtubule binding+++GO:0008013///beta-catenin binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0090630///activation of GTPase activity+++GO:0006413///translational initiation+++GO:0000226///microtubule cytoskeleton organization+++GO:0006364///rRNA processing+++GO:0001649///osteoblast differentiation+++GO:0016055///Wnt signaling pathway+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0042274///ribosomal small subunit biogenesis","APC2, WNT signaling pathway regulator","[APCL_HUMAN|Reviewed]RecName: Full=Adenomatous polyposis coli protein 2; AltName: Full=Adenomatous polyposis coli protein-like; Short=APC-like;"]
[10298,"'PAK4'",2403,2478,2742,2541,"04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++04012///ErbB signaling pathway+++04360///Axon guidance+++04660///T cell receptor signaling pathway+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005925///focal adhesion+++GO:0005913///cell-cell adherens junction+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0048365///Rac GTPase binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045766///positive regulation of angiogenesis+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0001558///regulation of cell growth+++GO:0006915///apoptotic process+++GO:0006468///protein phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0071407///cellular response to organic cyclic compound+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0060996///dendritic spine development+++GO:0023014///signal transduction by protein phosphorylation+++GO:0098609///cell-cell adhesion+++GO:0016477///cell migration+++GO:0043408///regulation of MAPK cascade+++GO:0016310///phosphorylation","p21 (RAC1) activated kinase 4","[PAK4_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 4; EC=2.7.11.1; AltName: Full=p21-activated kinase 4; Short=PAK-4;+++[A0A024R0J1_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[A0A024R0L8_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[B4DUG0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61413, highly similar to Serine/threonine-protein kinase PAK 4 {ECO:0000313|EMBL:BAG62322.1}; SubName: Full=p21(CDKN1A)-activated kinase 4, isoform CRA_e {ECO:0000313|EMBL:EAW56865.1};+++[M0R0L9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000471318}; Flags: Fragment;+++[M0R1R1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472061}; Flags: Fragment;+++[M0R2X4_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472862}; Flags: Fragment;+++[M0R3G6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000473215}; Flags: Fragment;"]
[10299,"'MARCH6'",1172,1045,1133,1116.66666666667,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0000835///ER ubiquitin ligase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0008270///zinc ion binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0061630///ubiquitin protein ligase activity","GO:0016567///protein ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0010498///proteasomal protein catabolic process+++GO:0036503///ERAD pathway+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:1904380///endoplasmic reticulum mannose trimming","membrane associated ring-CH-type finger 6","[MARH6_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MARCH6; EC=2.3.2.27; AltName: Full=Doa10 homolog; AltName: Full=Membrane-associated RING finger protein 6; AltName: Full=Membrane-associated RING-CH protein VI; Short=MARCH-VI; AltName: Full=Protein TEB-4; AltName: Full=RING finger protein 176; AltName: Full=RING-type E3 ubiquitin transferase MARCH6 {ECO:0000305};+++[A0A0B4J206_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000424512};+++[D6RHY7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000426000};"]
[103,"'ADAR'",3582.9,2189,2753.56,2841.82,"05162///Measles+++05164///Influenza A+++04623///Cytosolic DNA-sensing pathway","H00880///Dyschromatosis symmetrica hereditaria",null,null,"GO:0005634///nucleus+++GO:0044530///supraspliceosomal complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0003677///DNA binding+++GO:0003725///double-stranded RNA binding","GO:0006397///mRNA processing+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0016553///base conversion or substitution editing+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0006611///protein export from nucleus+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006396///RNA processing+++GO:0006606///protein import into nucleus+++GO:0006382///adenosine to inosine editing+++GO:0009615///response to virus+++GO:0035455///response to interferon-alpha+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060337///type I interferon signaling pathway+++GO:0031054///pre-miRNA processing+++GO:0031047///gene silencing by RNA","adenosine deaminase, RNA specific","[DSRAD_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific adenosine deaminase; Short=DRADA {ECO:0000303|PubMed:7972084}; EC=3.5.4.37 {ECO:0000269|PubMed:7565688, ECO:0000269|PubMed:7972084}; AltName: Full=136 kDa double-stranded RNA-binding protein; Short=p136; AltName: Full=Interferon-inducible protein 4; Short=IFI-4; AltName: Full=K88DSRBP;+++[A2IBT1_HUMAN|Unreviewed]SubName: Full=Truncated adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73519.1};+++[A2IBT2_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73520.1}; Flags: Fragment;+++[D3DV75_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase, RNA-specific, isoform CRA_b {ECO:0000313|EMBL:EAW53189.1};+++[H0YCK3_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific adenosine deaminase {ECO:0000313|Ensembl:ENSP00000431794}; Flags: Fragment;"]
[1030,"'CDKN2B'",9806,8763,7517,8695.33333333333,"04934///Cushing's syndrome+++04110///Cell cycle+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05166///HTLV-I infection+++04068///FoxO signaling pathway+++05226///Gastric cancer+++05222///Small cell lung cancer+++04350///TGF-beta signaling pathway+++04218///Cellular senescence","H00015///Malignant pleural mesothelioma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00409///Type II diabetes mellitus+++H01556///Meningioma",null,null,"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0016301///kinase activity","GO:0030219///megakaryocyte differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0031668///cellular response to extracellular stimulus+++GO:0016310///phosphorylation+++GO:0090398///cellular senescence+++GO:0007093///mitotic cell cycle checkpoint+++GO:0008285///negative regulation of cell proliferation+++GO:0048536///spleen development+++GO:0031670///cellular response to nutrient+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0042326///negative regulation of phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway","cyclin dependent kinase inhibitor 2B","[CDN2B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor B; AltName: Full=Multiple tumor suppressor 2; Short=MTS-2; AltName: Full=p14-INK4b; AltName: Full=p15-INK4b; Short=p15INK4B;+++[K7PPU3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AFN61601.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4), isoform CRA_b {ECO:0000313|EMBL:EAW58597.1}; SubName: Full=p15 {ECO:0000313|EMBL:AGC10270.1};+++[Q5ZEY8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:CAH59951.1};+++[Q8NIA6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AAF28397.1}; Flags: Fragment;"]
[10300,"'KATNB1'",636,663,705,668,null,"H00268///Lissencephaly (LIS)",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0030426///growth cone+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0030496///midbody+++GO:0005819///spindle+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0008352///katanin complex+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0030424///axon","GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0070840///dynein complex binding","GO:0051301///cell division+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0010942///positive regulation of cell death+++GO:0007019///microtubule depolymerization+++GO:0007049///cell cycle+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0051013///microtubule severing+++GO:0006605///protein targeting+++GO:0010976///positive regulation of neuron projection development","katanin regulatory subunit B1","[KTNB1_HUMAN|Reviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000255|HAMAP-Rule:MF_03022};+++[A0A024R6U1_HUMAN|Unreviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000256|HAMAP-Rule:MF_03022};+++[H3BPD8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455270}; Flags: Fragment;+++[H3BPK1_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455350}; Flags: Fragment;+++[H3BT67_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457046}; Flags: Fragment;+++[H3BTU7_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457334}; Flags: Fragment;+++[H3BTV8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457347}; Flags: Fragment;"]
[10302,"'SNAPC5'",132,124,141,132.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0006355///regulation of transcription, DNA-templated","small nuclear RNA activating complex polypeptide 5","[SNPC5_HUMAN|Reviewed]RecName: Full=snRNA-activating protein complex subunit 5; Short=SNAPc subunit 5; AltName: Full=Small nuclear RNA-activating complex polypeptide 5; AltName: Full=snRNA-activating protein complex 19 kDa subunit; Short=SNAPc 19 kDa subunit;+++[A0A024R5X1_HUMAN|Unreviewed]SubName: Full=Small nuclear RNA activating complex, polypeptide 5, 19kDa, isoform CRA_a {ECO:0000313|EMBL:EAW77772.1};+++[H3BQA0_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000455680};+++[H3BSI3_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000456716};"]
[10307,"'APBB3'",174,181,177,177.333333333333,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated","amyloid beta precursor protein binding family B member 3","[APBB3_HUMAN|Reviewed]RecName: Full=Amyloid-beta A4 precursor protein-binding family B member 3; AltName: Full=Protein Fe65-like 2; Short=Fe65L2;+++[B3KQG2_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3, isoform CRA_b {ECO:0000313|EMBL:EAW62042.1}; SubName: Full=cDNA FLJ43254 fis, clone HEART2008108, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG54172.1}; SubName: Full=cDNA FLJ90404 fis, clone NT2RP2006092, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG52024.1};+++[D6RBA1_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000424317};+++[D6RJB2_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000427272};+++[E7EX91_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000351389};+++[Q59EH2_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein-binding, family B, member 3 isoform b variant {ECO:0000313|EMBL:BAD93076.1}; Flags: Fragment;+++[Q86Z13_HUMAN|Unreviewed]SubName: Full=Fe65L2 isoform 339 {ECO:0000313|EMBL:BAC56948.1};+++[Q96DX9_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3 {ECO:0000313|EMBL:AAH13158.1};"]
[10308,"'ZNF267'",75,45,52,57.3333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 267","[ZN267_HUMAN|Reviewed]RecName: Full=Zinc finger protein 267; AltName: Full=Zinc finger protein HZF2;+++[H3BMG2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454369}; Flags: Fragment;+++[H3BNA3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454753}; Flags: Fragment;+++[H3BPW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000455493}; Flags: Fragment;+++[I3L4I6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000461286};"]
[10309,"'CCNO'",511,607,765,627.666666666667,null,"H00564///Primary ciliary dyskinesia",null,null,"GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity","GO:0045787///positive regulation of cell cycle+++GO:0060271///cilium assembly+++GO:0000278///mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042493///response to drug+++GO:1903251///multi-ciliated epithelial cell differentiation+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0006468///protein phosphorylation+++GO:0030030///cell projection organization+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division","cyclin O","[CCNO_HUMAN|Reviewed]RecName: Full=Cyclin-O;"]
[1031,"'CDKN2C'",5,7,3,5,"01522///Endocrine resistance+++04934///Cushing's syndrome+++04110///Cell cycle+++05202///Transcriptional misregulation in cancer+++05166///HTLV-I infection",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0019901///protein kinase binding","GO:0016310///phosphorylation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0042326///negative regulation of phosphorylation+++GO:0007049///cell cycle+++GO:0048709///oligodendrocyte differentiation+++GO:0007050///cell cycle arrest+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0008285///negative regulation of cell proliferation","cyclin dependent kinase inhibitor 2C","[CDN2C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor C; AltName: Full=Cyclin-dependent kinase 6 inhibitor; AltName: Full=p18-INK4c; AltName: Full=p18-INK6;+++[Q6ICV4_HUMAN|Unreviewed]SubName: Full=CDKN2C protein {ECO:0000313|EMBL:CAG29285.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2C (P18, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAX06833.1}; SubName: Full=cDNA FLJ33851 fis, clone CTONG2005635, highly similar to CYCLIN-DEPENDENT KINASE 6 INHIBITOR {ECO:0000313|EMBL:BAG52297.1}; Flags: Fragment;+++[Q9P1T2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2C {ECO:0000313|EMBL:AAF28398.1}; Flags: Fragment;"]
[10311,"'VPS26C'",460,434,461,451.666666666667,{"$nulls":4},"GO:0005768///endosome+++GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0008565///protein transporter activity","GO:0008150///biological_process+++GO:0006886///intracellular protein transport","VPS26 endosomal protein sorting factor C","[DSCR3_HUMAN|Reviewed]RecName: Full=Down syndrome critical region protein 3; AltName: Full=Down syndrome critical region protein A;+++[A8MTY9_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381964};+++[A8MY26_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381967}; SubName: Full=cDNA FLJ53689, highly similar to Down syndrome critical region protein 3 {ECO:0000313|EMBL:BAH14000.1};"]
[10312,"'TCIRG1'",648,674,538,620,"04721///Synaptic vesicle cycle+++05323///Rheumatoid arthritis+++05152///Tuberculosis+++04145///Phagosome+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04142///Lysosome+++00190///Oxidative phosphorylation+++04966///Collecting duct acid secretion+++01100///Metabolic pathways+++05110///Vibrio cholerae infection+++05165///Human papillomavirus infection","H00557///Cutis laxa+++H00428///Distal renal tubular acidosis (RTA type 1)+++H00436///Osteopetrosis","M00160///V-type ATPase, eukaryotes",null,"GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0005886///plasma membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030670///phagocytic vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0010008///endosome membrane+++GO:0005765///lysosomal membrane","GO:0051117///ATPase binding+++GO:0005215///transporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism","GO:0007035///vacuolar acidification+++GO:0006811///ion transport+++GO:0016236///macroautophagy+++GO:1902600///proton transmembrane transport+++GO:0006968///cellular defense response+++GO:0033572///transferrin transport+++GO:0034220///ion transmembrane transport+++GO:0007039///protein catabolic process in the vacuole+++GO:0043312///neutrophil degranulation+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0015991///ATP hydrolysis coupled proton transport","T cell immune regulator 1, ATPase H+ transporting V0 subunit a3","[VPP3_HUMAN|Reviewed]RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 3; Short=V-ATPase 116 kDa isoform a3; AltName: Full=Osteoclastic proton pump 116 kDa subunit; Short=OC-116 kDa; Short=OC116; AltName: Full=T-cell immune regulator 1; AltName: Full=T-cell immune response cDNA7 protein; Short=TIRC7; AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3;+++[A0A024R5E5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PM12_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[E9PMC5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PNA6_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YCE3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YEL3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q64F87_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN4_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 8 {ECO:0000313|EMBL:AAS59838.1}; Flags: Fragment;+++[Q6QBN5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN6_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 6 {ECO:0000313|EMBL:AAS59836.1}; Flags: Fragment;+++[Q6QBN7_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN8_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q8TCH1_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;"]
[10313,"'RTN3'",1642,1533,1744,1639.66666666667,"05010///Alzheimer's disease",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0071786///endoplasmic reticulum tubular network organization+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:0016032///viral process+++GO:0016192///vesicle-mediated transport+++GO:0006915///apoptotic process","reticulon 3","[RTN3_HUMAN|Reviewed]RecName: Full=Reticulon-3; AltName: Full=Homolog of ASY protein; Short=HAP; AltName: Full=Neuroendocrine-specific protein-like 2; Short=NSP-like protein 2; AltName: Full=Neuroendocrine-specific protein-like II; Short=NSP-like protein II; Short=NSPLII;+++[A0A024R5C4_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[B7Z4M1_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[F5GWG7_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000441614}; Flags: Fragment;+++[F5H617_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[F5H891_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000442080}; Flags: Fragment;+++[Q7RTN4_HUMAN|Unreviewed]SubName: Full=Truncated RTN3-A3 {ECO:0000313|EMBL:DAA01930.1};"]
[10314,"'LANCL1'",448,340,379,389,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0017124///SH3 domain binding+++GO:0008270///zinc ion binding+++GO:0043295///glutathione binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway","LanC like 1","[LANC1_HUMAN|Reviewed]RecName: Full=LanC-like protein 1; AltName: Full=40 kDa erythrocyte membrane protein; Short=p40;+++[A0A024R3Z5_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_b {ECO:0000313|EMBL:EAW70491.1};+++[B2R602_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92709, highly similar to Homo sapiens LanC lantibiotic synthetase component C-like 1 (bacterial) (LANCL1), mRNA {ECO:0000313|EMBL:BAG35299.1};+++[E9PHS0_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000396518}; Flags: Fragment;+++[F8WDS9_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000395442};+++[H7C2E3_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000405364}; Flags: Fragment;+++[Q53TN2_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_a {ECO:0000313|EMBL:EAW70487.1};+++[Q6FHH6_HUMAN|Unreviewed]SubName: Full=LANCL1 protein {ECO:0000313|EMBL:CAG46576.1}; Flags: Fragment;"]
[10316,"'NMUR1'",4,5,3,4,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0001607///neuromedin U receptor activity+++GO:0042924///neuromedin U binding","GO:0007202///activation of phospholipase C activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006816///calcium ion transport+++GO:0007165///signal transduction+++GO:0048016///inositol phosphate-mediated signaling+++GO:0006939///smooth muscle contraction+++GO:0019722///calcium-mediated signaling+++GO:0007218///neuropeptide signaling pathway+++GO:0006821///chloride transport","neuromedin U receptor 1","[NMUR1_HUMAN|Reviewed]RecName: Full=Neuromedin-U receptor 1; Short=NMU-R1; AltName: Full=G-protein coupled receptor 66; AltName: Full=G-protein coupled receptor FM-3;+++[L8E9D8_HUMAN|Unreviewed]SubName: Full=Alternative protein NMUR1 {ECO:0000313|EMBL:CCQ43346.1};"]
[10317,"'B3GALT5'",21,1,4,8.66666666666667,"01100///Metabolic pathways+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,"M00070///Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer","R05964///UDP-D-galactose + Globoside <=> UDP + Galactosylgloboside+++R06006///UDP-D-galactose + Lc3Cer <=> UDP + Lc4Cer","GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity","GO:0009312///oligosaccharide biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006486///protein glycosylation+++GO:0009617///response to bacterium","beta-1,3-galactosyltransferase 5","[B3GT5_HUMAN|Reviewed]RecName: Full=Beta-1,3-galactosyltransferase 5; Short=Beta-1,3-GalTase 5; Short=Beta3Gal-T5; Short=Beta3GalT5; Short=b3Gal-T5; EC=2.4.1.-; AltName: Full=Beta-3-Gx-T5; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5;+++[A0A0A0MS93_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};"]
[10318,"'TNIP1'",2478.07,2667,2474.99,2540.02,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0070034///telomerase RNA binding+++GO:0005515///protein binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0003723///RNA binding","GO:0043489///RNA stabilization+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0051973///positive regulation of telomerase activity+++GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0050727///regulation of inflammatory response+++GO:0006364///rRNA processing+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:0042254///ribosome biogenesis+++GO:0045071///negative regulation of viral genome replication+++GO:0006954///inflammatory response+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000493///box H/ACA snoRNP assembly+++GO:0001522///pseudouridine synthesis+++GO:0009101///glycoprotein biosynthetic process+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007159///leukocyte cell-cell adhesion+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0085032///modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade+++GO:0006952///defense response+++GO:1905323///telomerase holoenzyme complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090669///telomerase RNA stabilization+++GO:0050729///positive regulation of inflammatory response+++GO:0006412///translation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016579///protein deubiquitination","TNFAIP3 interacting protein 1","[TNIP1_HUMAN|Reviewed]RecName: Full=TNFAIP3-interacting protein 1; AltName: Full=A20-binding inhibitor of NF-kappa-B activation 1; Short=ABIN-1; AltName: Full=HIV-1 Nef-interacting protein; AltName: Full=Nef-associated factor 1; Short=Naf1; AltName: Full=Nip40-1; AltName: Full=Virion-associated nuclear shuttling protein; Short=VAN; Short=hVAN;+++[A0A0A0MRZ4_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000374029};+++[A8K4N4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77844, highly similar to Homo sapiens TNFAIP3 interacting protein 1, mRNA {ECO:0000313|EMBL:BAF83688.1};+++[B7Z8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61022, highly similar to Nef-associated factor 1 {ECO:0000313|EMBL:BAH13988.1};+++[E7EMV7_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427854};+++[E7EW15_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428487}; Flags: Fragment;+++[E7EW68_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430279}; Flags: Fragment;+++[E7EWG2_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428404}; Flags: Fragment;+++[H0YC17_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430739}; Flags: Fragment;"]
[10319,"'LAMC3'",2,9,5,5.33333333333333,"05146///Amoebiasis+++04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05145///Toxoplasmosis+++05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04510///Focal adhesion",{"$nulls":3},"GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005604///basement membrane","GO:0005198///structural molecule activity","GO:0030198///extracellular matrix organization+++GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0060041///retina development in camera-type eye+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0014002///astrocyte development","laminin subunit gamma 3","[LAMC3_HUMAN|Reviewed]RecName: Full=Laminin subunit gamma-3; AltName: Full=Laminin-12 subunit gamma; AltName: Full=Laminin-14 subunit gamma; AltName: Full=Laminin-15 subunit gamma; Flags: Precursor;+++[H7BY04_HUMAN|Unreviewed]SubName: Full=Laminin subunit gamma-3 {ECO:0000313|Ensembl:ENSP00000347627}; Flags: Fragment;+++[Q8N2D6_HUMAN|Unreviewed]SubName: Full=cDNA PSEC0236 fis, clone HEMBA1007104, highly similar to Laminin gamma-3 chain {ECO:0000313|EMBL:BAC11679.1};"]
[1032,"'CDKN2D'",50,51,32,44.3333333333333,"04068///FoxO signaling pathway+++04110///Cell cycle",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0097129///cyclin D2-CDK4 complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding","GO:0009411///response to UV+++GO:0033280///response to vitamin D+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0007605///sensory perception of sound+++GO:0042326///negative regulation of phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0007050///cell cycle arrest+++GO:0032526///response to retinoic acid+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:0007049///cell cycle+++GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","cyclin dependent kinase inhibitor 2D","[CDN2D_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor D; AltName: Full=p19-INK4d;+++[A0A024R796_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2D (P19, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAW84123.1};"]
[10320,"'IKZF1'",12,12,5,9.66666666666667,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0031618///nuclear pericentric heterochromatin+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding","GO:0030098///lymphocyte differentiation+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0051291///protein heterooligomerization+++GO:0006325///chromatin organization+++GO:0030218///erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007498///mesoderm development","IKAROS family zinc finger 1","[IKZF1_HUMAN|Reviewed]RecName: Full=DNA-binding protein Ikaros; AltName: Full=Ikaros family zinc finger protein 1; AltName: Full=Lymphoid transcription factor LyF-1;+++[A0A087WU46_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000478368};+++[A0A0A0MRA0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000340080};+++[A0A0A0MST1_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000401507};+++[A0A2R8Y4D3_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000493696};+++[A0A2R8Y4T7_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000494055}; Flags: Fragment;+++[A0A2R8YFR0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000496655}; Flags: Fragment;+++[C9JTB0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000388478};+++[Q3T907_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000409588}; SubName: Full=Zinc finger protein, subfamily 1A, 1 (Ikaros) {ECO:0000313|EMBL:CAJ29975.1}; Flags: Fragment;+++[Q9P1M1_HUMAN|Unreviewed]SubName: Full=PRO0758 {ECO:0000313|EMBL:AAF71030.1}; SubName: Full=Zinc finger protein, subfamily 1A, 1 (Ikaros), isoform CRA_c {ECO:0000313|EMBL:EAW60980.1};+++[R9R4D9_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000483016}; SubName: Full=IKAROS family zinc finger 1 isoform 14 {ECO:0000313|EMBL:AGI59420.1};"]
[10322,"'SMYD5'",405,421,470,432,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0032259///methylation+++GO:0008150///biological_process","SMYD family member 5","[SMYD5_HUMAN|Reviewed]RecName: Full=SET and MYND domain-containing protein 5; EC=2.1.1.-; AltName: Full=Protein NN8-4AG; AltName: Full=Retinoic acid-induced protein 15;+++[C9IYN9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000412587}; Flags: Fragment;+++[E2QRN5_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000258100};+++[F8WEJ9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000388195};"]
[10324,"'KLHL41'",6,4,6,5.33333333333333,null,"H00698///Nemaline myopathy",null,null,"GO:0016529///sarcoplasmic reticulum+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031143///pseudopodium+++GO:0001726///ruffle+++GO:0031430///M band+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0035914///skeletal muscle cell differentiation+++GO:2000291///regulation of myoblast proliferation+++GO:0048741///skeletal muscle fiber development+++GO:0006941///striated muscle contraction+++GO:0030239///myofibril assembly+++GO:0045214///sarcomere organization+++GO:0043687///post-translational protein modification+++GO:0031275///regulation of lateral pseudopodium assembly+++GO:0045661///regulation of myoblast differentiation+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0016567///protein ubiquitination","kelch like family member 41","[KLH41_HUMAN|Reviewed]RecName: Full=Kelch-like protein 41; AltName: Full=Kel-like protein 23; AltName: Full=Kelch repeat and BTB domain-containing protein 10; AltName: Full=Kelch-related protein 1; AltName: Full=Sarcosin;+++[Q3ZTS6_HUMAN|Unreviewed]SubName: Full=Sarcomeric muscle protein {ECO:0000313|EMBL:AAQ76811.1}; Flags: Fragment;"]
[10325,"'RRAGB'",344,305,255,301.333333333333,"04140///Autophagy - animal+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0034448///EGO complex+++GO:1990131///Gtr1-Gtr2 GTPase complex+++GO:0005765///lysosomal membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0051020///GTPase binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0032561///guanyl ribonucleotide binding","GO:1904263///positive regulation of TORC1 signaling+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0007050///cell cycle arrest+++GO:0034198///cellular response to amino acid starvation+++GO:0009267///cellular response to starvation+++GO:0034613///cellular protein localization+++GO:0010506///regulation of autophagy+++GO:0032006///regulation of TOR signaling+++GO:1990253///cellular response to leucine starvation","Ras related GTP binding B","[RRAGB_HUMAN|Reviewed]RecName: Full=Ras-related GTP-binding protein B {ECO:0000305}; Short=Rag B {ECO:0000303|PubMed:11073942}; Short=RagB {ECO:0000303|PubMed:7499430};+++[Q5VZM0_HUMAN|Unreviewed]SubName: Full=Ras-related GTP-binding protein B {ECO:0000313|Ensembl:ENSP00000410630}; Flags: Fragment;"]
[10327,"'AKR1A1'",952,1148,1009,1036.33333333333,"01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++00040///Pentose and glucuronate interconversions+++00561///Glycerolipid metabolism+++00930///Caprolactam degradation+++01130///Biosynthesis of antibiotics+++01220///Degradation of aromatic compounds+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis",null,"M00014///Glucuronate pathway (uronate pathway)","R01041///glycerol:NADP+ oxidoreductase   Glycerol + NADP+ <=> D-Glyceraldehyde + NADPH + H++++R05231///6-Hydroxyhexanoate:NADP+ oxidoreductase   6-Hydroxyhexanoic acid + NADP+ <=> Adipate semialdehyde + NADPH + H++++R00746///Ethanol:NADP+ oxidoreductase   Ethanol + NADP+ <=> Acetaldehyde + NADPH + H++++R01481///L-gulonate:NADP+ 6-oxidoreductase   L-Gulonate + NADP+ <=> D-Glucuronate + NADPH + H+","GO:0045202///synapse+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0009055///electron transfer activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0047939///L-glucuronate reductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0005515///protein binding+++GO:0016972///thiol oxidase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0016491///oxidoreductase activity","GO:0042840///D-glucuronate catabolic process+++GO:0022900///electron transport chain+++GO:0006081///cellular aldehyde metabolic process+++GO:0019853///L-ascorbic acid biosynthetic process+++GO:1901687///glutathione derivative biosynthetic process+++GO:0006006///glucose metabolic process+++GO:0055114///oxidation-reduction process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0046185///aldehyde catabolic process","aldo-keto reductase family 1 member A1","[AK1A1_HUMAN|Reviewed]RecName: Full=Alcohol dehydrogenase [NADP(+)]; EC=1.1.1.2; AltName: Full=Aldehyde reductase; AltName: Full=Aldo-keto reductase family 1 member A1;+++[Q5T621_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000398414}; Flags: Fragment;+++[Q9H2X5_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[Q9NY86_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[V9GYG2_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476713};+++[V9GYP9_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476978}; Flags: Fragment;+++[V9HWI0_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 6 {ECO:0000313|EMBL:ACF94472.1}; SubName: Full=Epididymis secretory sperm binding protein Li 165mP {ECO:0000313|EMBL:ACJ13642.1};"]
[10328,"'EMC8'",308,333,293,311.333333333333,"00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01100///Metabolic pathways+++05016///Huntington's disease+++04714///Thermogenesis+++04260///Cardiac muscle contraction+++05012///Parkinson's disease","H00920///Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis","M00154///Cytochrome c oxidase",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0072546///ER membrane protein complex","GO:0005515///protein binding",null,"ER membrane protein complex subunit 8","[EMC8_HUMAN|Reviewed]RecName: Full=ER membrane protein complex subunit 8; AltName: Full=Neighbor of COX4; AltName: Full=Protein FAM158B;+++[M0R1B0_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 8 {ECO:0000313|Ensembl:ENSP00000471751}; Flags: Fragment;+++[Q53Y03_HUMAN|Unreviewed]SubName: Full=COX4 neighbor, isoform CRA_a {ECO:0000313|EMBL:EAW95439.1}; SubName: Full=Neighbor of COX4 {ECO:0000313|EMBL:AAP35796.1}; SubName: Full=cDNA, FLJ94626, Homo sapiens neighbor of COX4 (NOC4), mRNA {ECO:0000313|EMBL:BAG36691.1};"]
[10329,"'RXYLT1'",168,171,215,184.666666666667,"00515///Mannose type O-glycan biosynthesis+++01100///Metabolic pathways","H00120///Muscular dystrophy-dystroglycanopathy type A",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane","GO:0016740///transferase activity+++GO:0120053///ribitol beta-1,4-xylosyltransferase activity","GO:0035269///protein O-linked mannosylation+++GO:0006486///protein glycosylation","ribitol xylosyltransferase 1","[RXLT1_HUMAN|Reviewed]RecName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000305}; EC=2.4.2.- {ECO:0000269|PubMed:27733679}; AltName: Full=Transmembrane protein 5 {ECO:0000305}; AltName: Full=UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase {ECO:0000303|PubMed:27733679};+++[F5GXF8_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440845};+++[G3V1K2_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440280}; SubName: Full=Transmembrane protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW97120.1};"]
[1033,"'CDKN3'",68,46,85,66.3333333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity","GO:0006470///protein dephosphorylation+++GO:0007050///cell cycle arrest+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0007049///cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle","cyclin dependent kinase inhibitor 3","[CDKN3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=CDK2-associated dual-specificity phosphatase; AltName: Full=Cyclin-dependent kinase interactor 1; AltName: Full=Cyclin-dependent kinase-interacting protein 2; AltName: Full=Kinase-associated phosphatase;+++[A0A087WW25_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000479875};+++[A0A087WWK3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[A0A0S2KP18_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 splice variant {ECO:0000313|EMBL:ALO50058.1};+++[F5H232_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000445572};+++[F8WD24_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000378944};+++[G3V1K6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000440404};+++[G3V2J7_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[H7C0S3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};"]
[10330,"'CNPY2'",2974,3283,2706,2987.66666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:0010629///negative regulation of gene expression+++GO:0045716///positive regulation of low-density lipoprotein particle receptor biosynthetic process","canopy FGF signaling regulator 2","[CNPY2_HUMAN|Reviewed]RecName: Full=Protein canopy homolog 2; AltName: Full=MIR-interacting saposin-like protein; AltName: Full=Putative secreted protein Zsig9; AltName: Full=Transmembrane protein 4; Flags: Precursor;+++[F8VXJ7_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448809}; Flags: Fragment;+++[F8W1K5_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000446784}; Flags: Fragment;+++[H0YI18_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448333}; Flags: Fragment;+++[H0YIH9_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000449444}; Flags: Fragment;"]
[10331,"'B3GNT3'",1,0,0,0.333333333333333,"01100///Metabolic pathways+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,null,"R04659///UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase   UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide+++R05974///UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + nLc7Cer+++R04636///UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->3)-[N-acetyl-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R 3-beta-N-acetyl-D-glucosaminyltransferase   UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R+++R05975///UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + nLc5Cer+++R05901///UDP-N-acetyl-D-glucosamine + G00025 <=> UDP + G00209","GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0000139///Golgi membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0047223///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity","GO:0018146///keratan sulfate biosynthetic process+++GO:0016266///O-glycan processing+++GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3","[B3GN3_HUMAN|Reviewed]RecName: Full=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; EC=2.4.1.149 {ECO:0000269|PubMed:11042166}; AltName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; EC=2.4.1.146 {ECO:0000269|PubMed:11439191}; AltName: Full=Beta-1,3-galactosyltransferase 8; Short=Beta-1,3-GalTase 8; Short=Beta3Gal-T8; Short=Beta3GalT8; Short=b3Gal-T8; AltName: Full=Beta-3-Gx-T8; AltName: Full=Core 1 extending beta-1,3-N-acetylglucosaminyltransferase {ECO:0000303|PubMed:11439191}; AltName: Full=Core1-beta3GlcNAcT {ECO:0000303|PubMed:11439191}; AltName: Full=Transmembrane protein 3; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; AltName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3; Short=BGnT-3; Short=Beta-1,3-Gn-T3; Short=Beta-1,3-N-acetylglucosaminyltransferase 3; Short=Beta3Gn-T3; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8;+++[M0QX58_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[M0R199_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;"]
[10333,"'TLR6'",13.48,7,16.21,12.23,"04620///Toll-like receptor signaling pathway+++05152///Tuberculosis+++05142///Chagas disease (American trypanosomiasis)+++04145///Phagosome",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0035355///Toll-like receptor 2-Toll-like receptor 6 protein complex+++GO:0045121///membrane raft+++GO:0030670///phagocytic vesicle membrane+++GO:0005794///Golgi apparatus","GO:0035663///Toll-like receptor 2 binding+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0071723///lipopeptide binding+++GO:0038023///signaling receptor activity+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0038124///toll-like receptor TLR6:TLR2 signaling pathway+++GO:0002376///immune system process+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0032493///response to bacterial lipoprotein+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:0046209///nitric oxide metabolic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043032///positive regulation of macrophage activation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045410///positive regulation of interleukin-6 biosynthetic process+++GO:2000483///negative regulation of interleukin-8 secretion+++GO:0045087///innate immune response+++GO:0002224///toll-like receptor signaling pathway+++GO:0001775///cell activation+++GO:0042742///defense response to bacterium+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:1904646///cellular response to amyloid-beta+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0034150///toll-like receptor 6 signaling pathway+++GO:0006954///inflammatory response+++GO:0042496///detection of diacyl bacterial lipopeptide+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0010628///positive regulation of gene expression+++GO:0001774///microglial cell activation+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0050707///regulation of cytokine secretion+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:0050702///interleukin-1 beta secretion+++GO:0071726///cellular response to diacyl bacterial lipopeptide","toll like receptor 6","[TLR6_HUMAN|Reviewed]RecName: Full=Toll-like receptor 6; AltName: CD_antigen=CD286; Flags: Precursor;+++[B2R933_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH37_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH42_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH44_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH45_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6RFS7_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS91_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS92_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS93_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS96_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS97_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS98_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS99_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CSA0_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D6R979_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000423326}; Flags: Fragment;+++[D6RAV7_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000424718}; Flags: Fragment;"]
[10335,"'MRVI1'",113,113,87,104.333333333333,"04270///Vascular smooth muscle contraction+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031095///platelet dense tubular network membrane","GO:0005515///protein binding",null,"murine retrovirus integration site 1 homolog","[MRVI1_HUMAN|Reviewed]RecName: Full=Protein MRVI1; AltName: Full=Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; AltName: Full=JAW1-related protein MRVI1;+++[E9PJ61_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000435658};+++[E9PNK7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000434741};+++[E9PRG4_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432325}; Flags: Fragment;+++[E9PRH0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432312};+++[H0YCL0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000431845}; Flags: Fragment;+++[H0YDM7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000433970}; Flags: Fragment;+++[H0YI08_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432067};"]
[10336,"'PCGF3'",696,666,628,663.333333333333,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0035102///PRC1 complex+++GO:0005634///nucleus+++GO:0031519///PcG protein complex+++GO:0000805///X chromosome+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding","GO:0060819///inactivation of X chromosome by genetic imprinting+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036353///histone H2A-K119 monoubiquitination","polycomb group ring finger 3","[PCGF3_HUMAN|Reviewed]RecName: Full=Polycomb group RING finger protein 3; AltName: Full=RING finger protein 3A;+++[A0A087WVH5_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000479441};+++[B3KQ06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32562 fis, clone SPLEN1000165, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG51868.1};+++[B3KWT8_HUMAN|Unreviewed]SubName: Full=Polycomb group ring finger 3, isoform CRA_b {ECO:0000313|EMBL:EAW82654.1}; SubName: Full=cDNA FLJ43813 fis, clone TESTI4001467, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG54250.1};+++[B4DTN5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54810, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG62047.1};+++[B5MEC4_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000383015};+++[C9J3G7_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000398493}; Flags: Fragment;+++[C9JGV3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000416279}; Flags: Fragment;+++[C9JYD0_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000401431}; Flags: Fragment;+++[F2Z3P3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000405840};"]
[10342,"'TFG'",3124,3284,3173,3193.66666666667,"05200///Pathways in cancer+++05216///Thyroid cancer","H00266///Hereditary spastic paraplegia (SPG)+++H00032///Thyroid cancer",null,null,"GO:0070971///endoplasmic reticulum exit site+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport","TRK-fused gene","[TFG_HUMAN|Reviewed]RecName: Full=Protein TFG; AltName: Full=TRK-fused gene protein;+++[C9JJP5_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000420797}; Flags: Fragment;+++[C9JTY3_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419559}; Flags: Fragment;+++[C9JUE0_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419504}; Flags: Fragment;+++[Q05BK6_HUMAN|Unreviewed]SubName: Full=TFG protein {ECO:0000313|EMBL:AAH41600.1};"]
[10343,"'PKDREJ'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding","GO:0006811///ion transport+++GO:0050982///detection of mechanical stimulus+++GO:0007340///acrosome reaction+++GO:0070588///calcium ion transmembrane transport","polycystin family receptor for egg jelly","[PKDRE_HUMAN|Reviewed]RecName: Full=Polycystic kidney disease and receptor for egg jelly-related protein; AltName: Full=PKD and REJ homolog; Flags: Precursor;"]
[10344,"'CCL26'",16,10,15,13.6666666666667,"04062///Chemokine signaling pathway+++04060///Cytokine-cytokine receptor interaction","H01361///Eosinophilic esophagitis+++H01360///Allergic rhinitis",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008009///chemokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity+++GO:0048020///CCR chemokine receptor binding+++GO:0005125///cytokine activity+++GO:0031728///CCR3 chemokine receptor binding","GO:0043547///positive regulation of GTPase activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0048245///eosinophil chemotaxis+++GO:0006955///immune response+++GO:0071347///cellular response to interleukin-1+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0006954///inflammatory response+++GO:0048247///lymphocyte chemotaxis+++GO:0007267///cell-cell signaling+++GO:0070098///chemokine-mediated signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0050921///positive regulation of chemotaxis+++GO:0006935///chemotaxis+++GO:0071346///cellular response to interferon-gamma+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0010818///T cell chemotaxis+++GO:0002548///monocyte chemotaxis","C-C motif chemokine ligand 26","[CCL26_HUMAN|Reviewed]RecName: Full=C-C motif chemokine 26; AltName: Full=CC chemokine IMAC; AltName: Full=Eotaxin-3; AltName: Full=Macrophage inflammatory protein 4-alpha; Short=MIP-4-alpha; AltName: Full=Small-inducible cytokine A26; AltName: Full=Thymic stroma chemokine-1; Short=TSC-1; Flags: Precursor;"]
[10345,"'TRDN'",6,9,9,8,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0030314///junctional membrane complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0030674///protein binding, bridging","GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0090158///endoplasmic reticulum membrane organization+++GO:0006936///muscle contraction+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0010649///regulation of cell communication by electrical coupling+++GO:1903779///regulation of cardiac conduction+++GO:0060047///heart contraction+++GO:0009617///response to bacterium+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0031122///cytoplasmic microtubule organization+++GO:1901846///positive regulation of cell communication by electrical coupling involved in cardiac conduction","triadin","[TRDN_HUMAN|Reviewed]RecName: Full=Triadin;+++[H0Y6P0_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000406768}; Flags: Fragment;+++[H7BY47_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000354307}; Flags: Fragment;+++[H9ME53_HUMAN|Unreviewed]SubName: Full=Cardiac triadin Trisk 32 isoform {ECO:0000313|EMBL:AEW10557.1}; SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000439281};+++[Q05C44_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH29393.1}; Flags: Fragment;+++[Q6PG49_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH57222.1}; Flags: Fragment;+++[Q8IVK2_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|EMBL:CAD33526.2};"]
[10346,"'TRIM22'",1377,1110,1169,1218.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0016740///transferase activity+++GO:0003714///transcription corepressor activity+++GO:0030674///protein binding, bridging+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0016032///viral process+++GO:0010508///positive regulation of autophagy+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0016567///protein ubiquitination+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0009615///response to virus+++GO:0032880///regulation of protein localization+++GO:0051607///defense response to virus+++GO:0070206///protein trimerization+++GO:0006955///immune response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity","tripartite motif containing 22","[TRI22_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM22; EC=2.3.2.27; AltName: Full=50 kDa-stimulated trans-acting factor; AltName: Full=RING finger protein 94; AltName: Full=RING-type E3 ubiquitin transferase TRIM22 {ECO:0000305}; AltName: Full=Staf-50; AltName: Full=Tripartite motif-containing protein 22;+++[B4DQS5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51049, highly similar to Tripartite motif-containing protein 22 {ECO:0000313|EMBL:BAG61037.1};+++[C9J060_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000400417}; Flags: Fragment;+++[C9JIU5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000396849}; Flags: Fragment;+++[C9JWC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000393250}; Flags: Fragment;+++[D3DQT0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_b {ECO:0000313|EMBL:EAW68770.1};+++[D3DQT1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_a {ECO:0000313|EMBL:EAW68768.1};+++[H7BZD3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000388994}; Flags: Fragment;+++[H7C262_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000404204}; Flags: Fragment;+++[H7C2K0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000406412}; Flags: Fragment;+++[H7C376_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000409991}; Flags: Fragment;+++[Q4A1P5_HUMAN|Unreviewed]SubName: Full=Tripartite binding motif 22 {ECO:0000313|EMBL:CAJ13842.1}; Flags: Fragment;"]
[10347,"'ABCA7'",1057,889,1261,1069,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0001891///phagocytic cup+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0090556///phosphatidylserine-translocating ATPase activity+++GO:0034188///apolipoprotein A-I receptor activity+++GO:0005515///protein binding+++GO:0005319///lipid transporter activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:1902430///negative regulation of amyloid-beta formation+++GO:0033700///phospholipid efflux+++GO:0033344///cholesterol efflux+++GO:0050766///positive regulation of phagocytosis+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0018149///peptide cross-linking+++GO:0055085///transmembrane transport+++GO:0010875///positive regulation of cholesterol efflux+++GO:1902995///positive regulation of phospholipid efflux+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034504///protein localization to nucleus+++GO:0006909///phagocytosis+++GO:0007613///memory+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901076///positive regulation of engulfment of apoptotic cell+++GO:0045332///phospholipid translocation+++GO:0006869///lipid transport","ATP binding cassette subfamily A member 7","[ABCA7_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 7; AltName: Full=ABCA-SSN; AltName: Full=Autoantigen SS-N; AltName: Full=Macrophage ABC transporter;+++[A0A087WUR5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000478857}; Flags: Fragment;+++[A0A087WX86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000480811}; Flags: Fragment;+++[A0A087WZX6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000482948}; Flags: Fragment;+++[B3KUJ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40025 fis, clone STOMA2008050, highly similar to Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 7 (ABCA7), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53455.1};+++[D6W5Y0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family A (ABC1), member 7, isoform CRA_e {ECO:0000313|EMBL:EAW69563.1};+++[E9PKG5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000433545}; Flags: Fragment;+++[E9PL63_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000431473}; Flags: Fragment;+++[H0YCN5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000432031}; Flags: Fragment;+++[H0YF58_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000437311}; Flags: Fragment;+++[L8EB07_HUMAN|Unreviewed]SubName: Full=Alternative protein ABCA7 {ECO:0000313|EMBL:CCQ43618.1};"]
[10349,"'ABCA10'",17,13,20,16.6666666666667,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005319///lipid transporter activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0006869///lipid transport+++GO:0055085///transmembrane transport","ATP binding cassette subfamily A member 10","[ABCAA_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 10;+++[E5RFN6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000428032};+++[E5RFP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000430341};+++[H0YBL8_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000429795}; Flags: Fragment;+++[K7EMH5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000466506}; Flags: Fragment;+++[K7ERP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000468351}; Flags: Fragment;"]
[10350,"'ABCA9'",7.42,3,8.94,6.45333333333333,"02010///ABC transporters",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005319///lipid transporter activity","GO:0055085///transmembrane transport+++GO:0006869///lipid transport","ATP binding cassette subfamily A member 9","[ABCA9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 9;+++[H0Y4U7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000394264};+++[K7EJJ0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000465191}; Flags: Fragment;"]
[10352,"'WARS2'",138,103,124,121.666666666667,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03664///L-Tryptophan -tRNA(Trp) ligase (AMP-forming)   ATP + L-Tryptophan + tRNA(Trp) <=> AMP + Diphosphate + L-Tryptophanyl-tRNA(Trp)","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000166///nucleotide binding+++GO:0004830///tryptophan-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding","GO:0006436///tryptophanyl-tRNA aminoacylation+++GO:0001570///vasculogenesis+++GO:0006412///translation+++GO:0070183///mitochondrial tryptophanyl-tRNA aminoacylation+++GO:0006418///tRNA aminoacylation for protein translation","tryptophanyl tRNA synthetase 2, mitochondrial","[SYWM_HUMAN|Reviewed]RecName: Full=Tryptophan--tRNA ligase, mitochondrial; EC=6.1.1.2; AltName: Full=(Mt)TrpRS; AltName: Full=Tryptophanyl-tRNA synthetase; Short=TrpRS; Flags: Precursor;+++[B7Z448_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51886, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH12434.1};+++[B7Z6G7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53098, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH13253.1};"]
[1036,"'CDO1'",471,382,607,486.666666666667,"00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00430///Taurine and hypotaurine metabolism",null,null,"R00893///L-Cysteine:oxygen oxidoreductase   L-Cysteine + Oxygen <=> 3-Sulfino-L-alanine","GO:0005829///cytosol","GO:0005506///iron ion binding+++GO:0017172///cysteine dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0008198///ferrous iron binding+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","GO:0010243///response to organonitrogen compound+++GO:0045471///response to ethanol+++GO:0051384///response to glucocorticoid+++GO:0019448///L-cysteine catabolic process+++GO:0043200///response to amino acid+++GO:0007595///lactation+++GO:0055114///oxidation-reduction process+++GO:0051591///response to cAMP+++GO:0000097///sulfur amino acid biosynthetic process+++GO:0006954///inflammatory response+++GO:0006534///cysteine metabolic process+++GO:0042412///taurine biosynthetic process+++GO:0033762///response to glucagon","cysteine dioxygenase type 1","[CDO1_HUMAN|Reviewed]RecName: Full=Cysteine dioxygenase type 1; EC=1.13.11.20; AltName: Full=Cysteine dioxygenase type I; Short=CDO; Short=CDO-I;"]
[10360,"'NPM3'",188,252,202,214,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0038023///signaling receptor activity","GO:0009303///rRNA transcription+++GO:0070267///oncosis+++GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing","nucleophosmin/nucleoplasmin 3","[NPM3_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-3;"]
[10361,"'NPM2'",5,2,2,3,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0000789///cytoplasmic chromatin+++GO:0000790///nuclear chromatin+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0042393///histone binding","GO:0007338///single fertilization+++GO:0009994///oocyte differentiation+++GO:0006325///chromatin organization+++GO:0051260///protein homooligomerization+++GO:0045740///positive regulation of DNA replication+++GO:0043085///positive regulation of catalytic activity+++GO:0001824///blastocyst development+++GO:0006338///chromatin remodeling+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0051054///positive regulation of DNA metabolic process+++GO:0007275///multicellular organism development+++GO:0007096///regulation of exit from mitosis","nucleophosmin/nucleoplasmin 2","[NPM2_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-2;+++[E5RFQ8_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000428016}; Flags: Fragment;+++[E5RGN1_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000429984}; Flags: Fragment;"]
[10362,"'HMG20B'",1554,1903,1574,1677,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016604///nuclear body+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004407///histone deacetylase activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0035914///skeletal muscle cell differentiation+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007596///blood coagulation+++GO:0033234///negative regulation of protein sumoylation+++GO:0045666///positive regulation of neuron differentiation","high mobility group 20B","[HM20B_HUMAN|Reviewed]RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; Short=SMARCE1-related protein; AltName: Full=BRCA2-associated factor 35; AltName: Full=HMG box-containing protein 20B; AltName: Full=HMG domain-containing protein 2; AltName: Full=HMG domain-containing protein HMGX2; AltName: Full=Sox-like transcriptional factor; AltName: Full=Structural DNA-binding protein BRAF35;+++[A4IF61_HUMAN|Unreviewed]SubName: Full=HMG20B protein {ECO:0000313|EMBL:AAI34414.1}; Flags: Fragment;+++[B5MDG7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000262949}; Flags: Fragment;+++[C9J8X5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000410924}; Flags: Fragment;+++[C9JQA7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000402877}; Flags: Fragment;+++[C9K049_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393904}; Flags: Fragment;+++[F8WES5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393481};+++[K7EJR8_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000465293}; Flags: Fragment;+++[Q8WYT5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein pp8857 {ECO:0000313|EMBL:AAL55873.1};"]
[10363,"'HMG20A'",658,544,598,600,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:0033234///negative regulation of protein sumoylation+++GO:0045665///negative regulation of neuron differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006325///chromatin organization","high mobility group 20A","[HM20A_HUMAN|Reviewed]RecName: Full=High mobility group protein 20A; AltName: Full=HMG box-containing protein 20A; AltName: Full=HMG domain-containing protein 1; AltName: Full=HMG domain-containing protein HMGX1;+++[B4DMG1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57155, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAG59873.1}; SubName: Full=cDNA, FLJ79180, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAH14652.1};+++[H0YK55_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452665}; Flags: Fragment;+++[H0YKL0_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452847}; Flags: Fragment;+++[H0YKM5_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452864}; Flags: Fragment;+++[H0YM80_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453498}; Flags: Fragment;+++[H0YMG2_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453592};+++[H0YMS9_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453727}; Flags: Fragment;+++[H0YNS8_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000454136}; Flags: Fragment;"]
[10365,"'KLF2'",38,51,26,38.3333333333333,"05418///Fluid shear stress and atherosclerosis+++04371///Apelin signaling pathway+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0001701///in utero embryonic development+++GO:0070301///cellular response to hydrogen peroxide+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:0043249///erythrocyte maturation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060509///type I pneumocyte differentiation+++GO:0071498///cellular response to fluid shear stress+++GO:0035264///multicellular organism growth+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071409///cellular response to cycloheximide+++GO:0032715///negative regulation of interleukin-6 production+++GO:0000902///cell morphogenesis+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0034616///response to laminar fluid shear stress+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0040029///regulation of gene expression, epigenetic+++GO:1901653///cellular response to peptide+++GO:0071347///cellular response to interleukin-1+++GO:0051247///positive regulation of protein metabolic process+++GO:0034101///erythrocyte homeostasis+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0097533///cellular stress response to acid chemical+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0000122///negative regulation of transcription by RNA polymerase II","Kruppel like factor 2","[KLF2_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 2; AltName: Full=Lung krueppel-like factor;+++[K7EJ60_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 2 {ECO:0000313|Ensembl:ENSP00000465035};"]
[10367,"'MICU1'",1010,1059,1073,1047.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0032592///integral component of mitochondrial membrane+++GO:0034704///calcium channel complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005622///intracellular+++GO:1990246///uniplex complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0042802///identical protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0070509///calcium ion import+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051260///protein homooligomerization+++GO:0006952///defense response+++GO:0036444///calcium import into the mitochondrion+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0006851///mitochondrial calcium ion transmembrane transport","mitochondrial calcium uptake 1","[MICU1_HUMAN|Reviewed]RecName: Full=Calcium uptake protein 1, mitochondrial; AltName: Full=Atopy-related autoantigen CALC {ECO:0000303|PubMed:16002733}; Short=ara CALC {ECO:0000303|PubMed:16002733}; AltName: Full=Calcium-binding atopy-related autoantigen 1 {ECO:0000303|PubMed:16002733}; AltName: Allergen=Hom s 4 {ECO:0000303|PubMed:16002733}; Flags: Precursor;+++[A0A0U1RRK1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000489563};+++[A0A286YF11_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000493232};+++[E9PQV6_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000432492}; Flags: Fragment;+++[F6XEV2_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000381745};+++[S4R3D7_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474192}; Flags: Fragment;+++[S4R3V1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474775}; Flags: Fragment;+++[S4R3W3_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474809}; Flags: Fragment;"]
[10369,"'CACNG2'",0,1,0,0.333333333333333,"04260///Cardiac muscle contraction+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04921///Oxytocin signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04010///MAPK signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++05410///Hypertrophic cardiomyopathy (HCM)","H00773///Autosomal dominant mental retardation",null,null,"GO:0045202///synapse+++GO:0044300///cerebellar mossy fiber+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0032281///AMPA glutamate receptor complex+++GO:0016020///membrane+++GO:0030666///endocytic vesicle membrane+++GO:0098978///glutamatergic synapse+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0036477///somatodendritic compartment+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:0043005///neuron projection+++GO:0005891///voltage-gated calcium channel complex+++GO:0014069///postsynaptic density+++GO:0016021///integral component of membrane+++GO:0098839///postsynaptic density membrane","GO:0005244///voltage-gated ion channel activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0016247///channel regulator activity+++GO:0005515///protein binding+++GO:0005262///calcium channel activity+++GO:0005245///voltage-gated calcium channel activity","GO:2000969///positive regulation of AMPA receptor activity+++GO:0099590///neurotransmitter receptor internalization+++GO:0006816///calcium ion transport+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0034765///regulation of ion transmembrane transport+++GO:0051592///response to calcium ion+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:1904510///positive regulation of protein localization to basolateral plasma membrane+++GO:0007528///neuromuscular junction development+++GO:2000311///regulation of AMPA receptor activity+++GO:0050877///nervous system process+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0019226///transmission of nerve impulse+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0060081///membrane hyperpolarization+++GO:0006612///protein targeting to membrane+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0060082///eye blink reflex+++GO:0042391///regulation of membrane potential+++GO:0006811///ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0051899///membrane depolarization","calcium voltage-gated channel auxiliary subunit gamma 2","[CCG2_HUMAN|Reviewed]RecName: Full=Voltage-dependent calcium channel gamma-2 subunit; AltName: Full=Neuronal voltage-gated calcium channel gamma-2 subunit; AltName: Full=Transmembrane AMPAR regulatory protein gamma-2; Short=TARP gamma-2;"]
[10370,"'CITED2'",3388,3041,3350,3259.66666666667,"04137///Mitophagy - animal","H01926///Ventricular septal defect (VSD)+++H00546///Atrial septal defect",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin","GO:0046332///SMAD binding+++GO:0050693///LBD domain binding+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding+++GO:0035035///histone acetyltransferase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding","GO:0007417///central nervous system development+++GO:0070986///left/right axis specification+++GO:0060411///cardiac septum morphogenesis+++GO:0009612///response to mechanical stimulus+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0034405///response to fluid shear stress+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030851///granulocyte differentiation+++GO:0003197///endocardial cushion development+++GO:0007507///heart development+++GO:0008584///male gonad development+++GO:0061308///cardiac neural crest cell development involved in heart development+++GO:0043066///negative regulation of apoptotic process+++GO:2000020///positive regulation of male gonad development+++GO:0060349///bone morphogenesis+++GO:0021602///cranial nerve morphogenesis+++GO:0048821///erythrocyte development+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0048538///thymus development+++GO:0007530///sex determination+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0001947///heart looping+++GO:0045787///positive regulation of cell cycle+++GO:0035914///skeletal muscle cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0061371///determination of heart left/right asymmetry+++GO:0001944///vasculature development+++GO:0001889///liver development+++GO:0001701///in utero embryonic development+++GO:0007422///peripheral nervous system development+++GO:0001829///trophectodermal cell differentiation+++GO:0008283///cell proliferation+++GO:0001570///vasculogenesis+++GO:0001568///blood vessel development+++GO:0001841///neural tube formation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0030325///adrenal gland development+++GO:0003156///regulation of animal organ formation+++GO:0035802///adrenal cortex formation+++GO:0003151///outflow tract morphogenesis+++GO:0043627///response to estrogen+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:1900164///nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0071363///cellular response to growth factor stimulus+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0007275///multicellular organism development+++GO:0030336///negative regulation of cell migration+++GO:0007368///determination of left/right symmetry+++GO:0060412///ventricular septum morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001666///response to hypoxia+++GO:0048536///spleen development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002521///leukocyte differentiation+++GO:0001843///neural tube closure+++GO:0007569///cell aging+++GO:0001892///embryonic placenta development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0003281///ventricular septum development+++GO:0061156///pulmonary artery morphogenesis+++GO:0046697///decidualization+++GO:0060136///embryonic process involved in female pregnancy","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2","[CITE2_HUMAN|Reviewed]RecName: Full=Cbp/p300-interacting transactivator 2; AltName: Full=MSG-related protein 1; Short=MRG-1; AltName: Full=P35srj;+++[A0A0A0MTM3_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator 2 {ECO:0000313|Ensembl:ENSP00000444198};+++[D9ZGF1_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 {ECO:0000313|EMBL:ADL14510.1}; SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, isoform CRA_d {ECO:0000313|EMBL:EAW47894.1};"]
[10371,"'SEMA3A'",334,203,297,278,"04360///Axon guidance","H00556///CHARGE syndrome+++H00255///Hypogonadotropic hypogonadism","M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin","GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030424///axon+++GO:0005887///integral component of plasma membrane+++GO:0030425///dendrite","GO:0045499///chemorepellent activity+++GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding","GO:0002027///regulation of heart rate+++GO:0001764///neuron migration+++GO:0021637///trigeminal nerve structural organization+++GO:0050919///negative chemotaxis+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:0021675///nerve development+++GO:0006915///apoptotic process+++GO:0048846///axon extension involved in axon guidance+++GO:0007411///axon guidance+++GO:0048813///dendrite morphogenesis+++GO:0030517///negative regulation of axon extension+++GO:0021785///branchiomotor neuron axon guidance+++GO:0060385///axonogenesis involved in innervation+++GO:0007413///axonal fasciculation+++GO:0048841///regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:1903045///neural crest cell migration involved in sympathetic nervous system development+++GO:0061549///sympathetic ganglion development+++GO:0001755///neural crest cell migration+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:0061551///trigeminal ganglion development+++GO:0046330///positive regulation of JNK cascade+++GO:0021612///facial nerve structural organization+++GO:2001224///positive regulation of neuron migration+++GO:0021772///olfactory bulb development+++GO:0030335///positive regulation of cell migration+++GO:0097490///sympathetic neuron projection extension+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0150020///basal dendrite arborization+++GO:0010633///negative regulation of epithelial cell migration+++GO:0048880///sensory system development+++GO:0010977///negative regulation of neuron projection development+++GO:0008045///motor neuron axon guidance+++GO:0007275///multicellular organism development+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:2000020///positive regulation of male gonad development+++GO:0097491///sympathetic neuron projection guidance+++GO:1903375///facioacoustic ganglion development+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030154///cell differentiation+++GO:0036486///ventral trunk neural crest cell migration+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048485///sympathetic nervous system development","semaphorin 3A","[SEM3A_HUMAN|Reviewed]RecName: Full=Semaphorin-3A; AltName: Full=Semaphorin III; Short=Sema III; Flags: Precursor;+++[A0A0C4DG50_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000402093}; Flags: Fragment;+++[C9J9C4_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000391900}; Flags: Fragment;+++[C9JD25_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000404800}; Flags: Fragment;+++[Q75MQ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAS02028.1}; Flags: Fragment;+++[Q86UJ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAP22350.1}; Flags: Fragment;"]
[10376,"'TUBA1B'",8520.15,9453.06,9563.63,9178.94666666666,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection+++04530///Tight junction+++04210///Apoptosis","H00058///Amyotrophic lateral sclerosis (ALS)+++H00268///Lissencephaly (LIS)+++H00271///Polymicrogyria",null,null,"GO:0005874///microtubule+++GO:0045121///membrane raft+++GO:0015630///microtubule cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath","GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007017///microtubule-based process+++GO:0000278///mitotic cell cycle+++GO:0071353///cellular response to interleukin-4+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0000226///microtubule cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0051301///cell division","tubulin alpha 1b","[TBA1B_HUMAN|Reviewed]RecName: Full=Tubulin alpha-1B chain; AltName: Full=Alpha-tubulin ubiquitous; AltName: Full=Tubulin K-alpha-1; AltName: Full=Tubulin alpha-ubiquitous chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1B chain;+++[F8VRK0_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448648}; Flags: Fragment;+++[F8VU66_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448045};+++[F8VVB9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449325}; Flags: Fragment;+++[F8VWV9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449460}; Flags: Fragment;+++[F8VX09_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449748}; Flags: Fragment;"]
[10379,"'IRF9'",787,796,681,754.666666666667,"05164///Influenza A+++04630///Jak-STAT signaling pathway+++05160///Hepatitis C+++05162///Measles+++05165///Human papillomavirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05168///Herpes simplex infection+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++05203///Viral carcinogenesis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity","GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0007166///cell surface receptor signaling pathway+++GO:0060337///type I interferon signaling pathway","interferon regulatory factor 9","[IRF9_HUMAN|Reviewed]RecName: Full=Interferon regulatory factor 9; Short=IRF-9; AltName: Full=IFN-alpha-responsive transcription factor subunit; AltName: Full=ISGF3 p48 subunit; AltName: Full=Interferon-stimulated gene factor 3 gamma; Short=ISGF-3 gamma; AltName: Full=Transcriptional regulator ISGF3 subunit gamma;+++[H0YMB0_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453534};+++[H0YMB6_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453540}; Flags: Fragment;+++[H0YNM9_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454078};+++[H0YNP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454095}; Flags: Fragment;+++[H7BXP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000313529}; Flags: Fragment;"]
[10380,"'BPNT1'",241,243,291,258.333333333333,"01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++00920///Sulfur metabolism+++01130///Biosynthesis of antibiotics",null,null,"R00508///3'-phospho-5'-adenylyl sulfate 3'-phosphohydrolase   3'-Phosphoadenylyl sulfate + H2O <=> Adenylyl sulfate + Orthophosphate+++R00188///adenosine-3',5'-bisphosphate 3'-phosphohydrolase   Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate","GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005615///extracellular space","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008441///3'(2'),5'-bisphosphate nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0019864///IgG binding+++GO:0004190///aspartic-type endopeptidase activity+++GO:0046983///protein dimerization activity+++GO:0003779///actin binding","GO:0070233///negative regulation of T cell apoptotic process+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0010628///positive regulation of gene expression+++GO:0055085///transmembrane transport+++GO:0001895///retina homeostasis+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0007399///nervous system development+++GO:0016311///dephosphorylation+++GO:0006508///proteolysis+++GO:0046854///phosphatidylinositol phosphorylation","3'(2'), 5'-bisphosphate nucleotidase 1","[BPNT1_HUMAN|Reviewed]RecName: Full=3'(2'),5'-bisphosphate nucleotidase 1; EC=3.1.3.7; AltName: Full=Bisphosphate 3'-nucleotidase 1; AltName: Full=PAP-inositol 1,4-phosphatase; Short=PIP;+++[A6NF51_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000346862};+++[B7Z9J7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78861, highly similar to 3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|EMBL:BAH14333.1};+++[F8VRY7_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000448740}; Flags: Fragment;+++[F8VVW8_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000449883}; Flags: Fragment;+++[F8VZG4_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446850}; Flags: Fragment;+++[F8W1J0_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446953}; Flags: Fragment;+++[V9HWF9_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 20 {ECO:0000313|EMBL:ACJ13648.1}; SubName: Full=Testicular tissue protein Li 29 {ECO:0000313|EMBL:AEE60942.1};"]
[10381,"'TUBB3'",6563.67,7082.87,6285.68,6644.07333333333,"04540///Gap junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H01579///Congenital symmetric circumferential skin creases+++H01740///Macrothrombocytopenia+++H00679///Hypomyelinating leukodystrophy+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect+++H00271///Polymicrogyria+++H01881///Complex cortical dysplasia with other brain malformations",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030424///axon","GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007017///microtubule-based process+++GO:0007411///axon guidance+++GO:0000278///mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0030182///neuron differentiation+++GO:0007010///cytoskeleton organization","tubulin beta 3 class III","[TBB3_HUMAN|Reviewed]RecName: Full=Tubulin beta-3 chain; AltName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin beta-III;+++[G3V2A3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[G3V2N6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_d {ECO:0000313|EMBL:EAW66672.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450765};+++[G3V2R8_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_e {ECO:0000313|EMBL:EAW66673.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450822};+++[G3V3J6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_b {ECO:0000313|EMBL:EAW66670.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451276};+++[G3V3R4_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_c {ECO:0000313|EMBL:EAW66671.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451378};+++[G3V3W7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451465};+++[G3V4U2_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451985};+++[G3V542_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452166}; Flags: Fragment;+++[G3V5W4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452554};+++[Q3ZCR3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q53G92_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q9BV28_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;"]
[10382,"'TUBB4A'",4287,4810,6672,5256.33333333333,"05130///Pathogenic Escherichia coli infection+++04540///Gap junction+++04145///Phagosome","H00679///Hypomyelinating leukodystrophy+++H01740///Macrothrombocytopenia+++H01881///Complex cortical dysplasia with other brain malformations+++H01897///Oocyte maturation defect+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01579///Congenital symmetric circumferential skin creases+++H00271///Polymicrogyria",null,null,"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005929///cilium+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0033269///internode region of axon+++GO:0042995///cell projection+++GO:0005930///axoneme+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005509///calcium ion binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007010///cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0031115///negative regulation of microtubule polymerization","tubulin beta 4A class IVa","[TBB4A_HUMAN|Reviewed]RecName: Full=Tubulin beta-4A chain; AltName: Full=Tubulin 5 beta; AltName: Full=Tubulin beta-4 chain;+++[M0QX14_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000468843};+++[M0QY37_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469560};+++[M0QY85_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469660}; Flags: Fragment;+++[M0QYM7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469936}; Flags: Fragment;+++[M0QZL7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000470627}; Flags: Fragment;+++[M0R042_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R0M1_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471320};+++[M0R0X0_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471503};+++[M0R1I1_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R278_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472375}; Flags: Fragment;+++[M0R2D3_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472481}; Flags: Fragment;+++[M0R2T4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472795};"]
[10383,"'TUBB4B'",4384.47,4715.96,5285.86,4795.43,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection","H01579///Congenital symmetric circumferential skin creases+++H00679///Hypomyelinating leukodystrophy+++H01881///Complex cortical dysplasia with other brain malformations+++H01740///Macrothrombocytopenia+++H00271///Polymicrogyria+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect",null,null,"GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:1903561///extracellular vesicle+++GO:0035578///azurophil granule lumen+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005576///extracellular region","GO:0005200///structural constituent of cytoskeleton+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0042288///MHC class I protein binding+++GO:0005525///GTP binding+++GO:0051082///unfolded protein binding+++GO:0000166///nucleotide binding","GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0043312///neutrophil degranulation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0000226///microtubule cytoskeleton organization","tubulin beta 4B class IVb","[TBB4B_HUMAN|Reviewed]RecName: Full=Tubulin beta-4B chain; AltName: Full=Tubulin beta-2 chain; AltName: Full=Tubulin beta-2C chain;+++[Q8IZ29_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q8N6N5_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q96HX0_HUMAN|Unreviewed]SubName: Full=TUBB2C protein {ECO:0000313|EMBL:AAH08006.1}; Flags: Fragment;"]
[10384,"'BTN3A3'",62.99,41.29,49,51.0933333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding","GO:0050852///T cell receptor signaling pathway+++GO:0050776///regulation of immune response+++GO:0002376///immune system process+++GO:0006366///transcription by RNA polymerase II+++GO:0002250///adaptive immune response+++GO:0015031///protein transport+++GO:0002456///T cell mediated immunity+++GO:0001701///in utero embryonic development","butyrophilin subfamily 3 member A3","[BT3A3_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 3 member A3; Flags: Precursor;+++[A0A024R042_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 3, member A3, isoform CRA_b {ECO:0000313|EMBL:EAW55574.1};+++[A0A089GIA6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 secreted isoform {ECO:0000313|EMBL:AIP98384.1};+++[C9J3Q8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417234}; Flags: Fragment;+++[C9J877_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417717}; Flags: Fragment;+++[C9JNZ3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420339}; Flags: Fragment;+++[C9JQT8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420147}; Flags: Fragment;+++[C9JUV8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419445}; Flags: Fragment;+++[C9JVU4_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419312}; Flags: Fragment;+++[C9JZT5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419736}; Flags: Fragment;+++[D6RDG3_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;+++[H0Y9Y1_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;"]
[10385,"'BTN2A2'",203,214,255,224,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0050776///regulation of immune response+++GO:0031324///negative regulation of cellular metabolic process+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0050710///negative regulation of cytokine secretion","butyrophilin subfamily 2 member A2","[BT2A2_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 2 member A2; Flags: Precursor;+++[A0A024R038_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 2, member A2, isoform CRA_a {ECO:0000313|EMBL:EAW55564.1};+++[C9IY66_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418857}; Flags: Fragment;+++[C9IZY2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418965}; Flags: Fragment;+++[C9J8J5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418176}; Flags: Fragment;+++[C9J8R3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417676}; Flags: Fragment;+++[C9JAJ6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417511}; Flags: Fragment;+++[C9JWH2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000419226}; Flags: Fragment;+++[F8WC65_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418657};+++[H7C4E8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417129}; Flags: Fragment;"]
[10388,"'SYCP2'",6,2,6,4.66666666666667,{"$nulls":4},"GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000800///lateral element+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0000795///synaptonemal complex+++GO:0005694///chromosome+++GO:0032991///protein-containing complex","GO:0033814///propanoyl-CoA C-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0005102///signaling receptor binding+++GO:0050632///propionyl-CoA C2-trimethyltridecanoyltransferase activity+++GO:0000062///fatty-acyl-CoA binding+++GO:0003824///catalytic activity+++GO:0008289///lipid binding+++GO:0046982///protein heterodimerization activity+++GO:0070538///oleic acid binding","GO:0006701///progesterone biosynthetic process+++GO:1901373///lipid hydroperoxide transport+++GO:0072659///protein localization to plasma membrane+++GO:0007049///cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0007140///male meiotic nuclear division+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0045940///positive regulation of steroid metabolic process+++GO:0007143///female meiotic nuclear division+++GO:0036109///alpha-linolenic acid metabolic process+++GO:0009566///fertilization+++GO:0006699///bile acid biosynthetic process+++GO:0032385///positive regulation of intracellular cholesterol transport+++GO:0006869///lipid transport+++GO:0007031///peroxisome organization+++GO:0015914///phospholipid transport+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0051301///cell division+++GO:0006694///steroid biosynthetic process+++GO:0009887///animal organ morphogenesis+++GO:0048808///male genitalia morphogenesis+++GO:0051321///meiotic cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0006625///protein targeting to peroxisome","synaptonemal complex protein 2","[SYCP2_HUMAN|Reviewed]RecName: Full=Synaptonemal complex protein 2; Short=SCP-2; AltName: Full=Synaptonemal complex lateral element protein; Short=hsSCP2;+++[A2A2M9_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000399300}; Flags: Fragment;+++[A2A340_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000404358}; Flags: Fragment;+++[A2A341_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000402456}; Flags: Fragment;+++[A6QL60_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAI46799.1}; Flags: Fragment;+++[H0YCB0_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000431279}; Flags: Fragment;+++[H0YD06_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000432645}; Flags: Fragment;+++[H0YEU8_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000436581}; Flags: Fragment;+++[H0YF61_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000437317}; Flags: Fragment;+++[L0R5C7_HUMAN|Unreviewed]SubName: Full=Alternative protein SCP2 {ECO:0000313|EMBL:CCO13809.1};+++[Q8IWA1_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAH40566.1}; Flags: Fragment;"]
[10389,"'SCML2'",4,1,18,7.66666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0031519///PcG protein complex","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0009653///anatomical structure morphogenesis","Scm polycomb group protein like 2","[SCML2_HUMAN|Reviewed]RecName: Full=Sex comb on midleg-like protein 2;+++[H0Y6S1_HUMAN|Unreviewed]SubName: Full=Sex comb on midleg-like protein 2 {ECO:0000313|Ensembl:ENSP00000407315}; Flags: Fragment;"]
[1039,"'CDR2'",1039,859,1043,980.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","cerebellar degeneration related protein 2","[CDR2_HUMAN|Reviewed]RecName: Full=Cerebellar degeneration-related protein 2; AltName: Full=Major Yo paraneoplastic antigen; AltName: Full=Paraneoplastic cerebellar degeneration-associated antigen;+++[H3BN65_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000454706}; Flags: Fragment;+++[H3BQS4_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000455915};+++[H3BTR1_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457289}; Flags: Fragment;+++[H3BU23_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457432}; Flags: Fragment;+++[H3BUE0_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457596}; Flags: Fragment;"]
[10390,"'CEPT1'",138,110,96,114.666666666667,"01100///Metabolic pathways+++00564///Glycerophospholipid metabolism+++00440///Phosphonate and phosphinate metabolism+++00565///Ether lipid metabolism+++01110///Biosynthesis of secondary metabolites","H00481///Cone-rod dystrophy and cone dystrophy","M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE+++M00090///Phosphatidylcholine (PC) biosynthesis, choline => PC","R04321///CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase   CDP-choline + 1-Alkyl-2-acetyl-sn-glycerol <=> CMP + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine+++R04922///CMP-N-trimethyl-2-aminoethylphosphonate:1,2-diacylglycerol (N-trimethyl-2-aminoethylphosphonyl)transferase   CMP-N-trimethyl-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate+++R02057///CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine+++R07389///1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP+++R04920///CMP-2-aminoethylphosphonate:1,2-diacylglycerol (2-aminoethylphosphonyl)transferase   CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate+++R07384///O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine+++R01321///CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase   CDP-choline + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylcholine+++R06364///CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine","GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane","GO:0004142///diacylglycerol cholinephosphotransferase activity+++GO:0046872///metal ion binding+++GO:0004307///ethanolaminephosphotransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups","GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006657///CDP-choline pathway+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process","choline/ethanolamine phosphotransferase 1","[CEPT1_HUMAN|Reviewed]RecName: Full=Choline/ethanolaminephosphotransferase 1; Short=hCEPT1; EC=2.7.8.1; EC=2.7.8.2;+++[A0A024R0C0_HUMAN|Unreviewed]SubName: Full=Choline/ethanolamine phosphotransferase 1, isoform CRA_b {ECO:0000313|EMBL:EAW56472.1};+++[A0A0C4DGS9_HUMAN|Unreviewed]SubName: Full=Choline/ethanolaminephosphotransferase 1 {ECO:0000313|Ensembl:ENSP00000477632};"]
[10391,"'CORO2B'",424,435,650,503,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding","GO:0030036///actin cytoskeleton organization","coronin 2B","[COR2B_HUMAN|Reviewed]RecName: Full=Coronin-2B; AltName: Full=Coronin-like protein C; Short=Clipin-C; AltName: Full=Protein FC96;"]
[103910,"'MYL12B'",4399,4642,4271,4437.33333333333,"04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++04611///Platelet activation",{"$nulls":3},"GO:0099738///cell cortex region+++GO:0045177///apical part of cell+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005903///brush border+++GO:0001725///stress fiber+++GO:0070062///extracellular exosome","GO:0032036///myosin heavy chain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0008360///regulation of cell shape","myosin light chain 12B","[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;"]
[10392,"'NOD1'",76,86,71,77.6666666666667,"04621///NOD-like receptor signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05133///Pertussis+++05131///Shigellosis","H01358///Atopic dermatitis",null,"R03749///(5-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxoproline-forming) (5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid+++R02743///gamma-L-glutamyl-L-cysteine gamma-glutamyl cyclotransferase (5-oxoproline-forming) gamma-L-Glutamyl-L-cysteine <=> 5-Oxoproline + L-Cysteine","GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0042834///peptidoglycan binding+++GO:0050700///CARD domain binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0042802///identical protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0000187///activation of MAPK activity+++GO:0002376///immune system process+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0009595///detection of biotic stimulus+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0016045///detection of bacterium+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0042981///regulation of apoptotic process+++GO:0007165///signal transduction+++GO:0042742///defense response to bacterium+++GO:1904417///positive regulation of xenophagy+++GO:0006915///apoptotic process+++GO:0071225///cellular response to muramyl dipeptide+++GO:0050830///defense response to Gram-positive bacterium+++GO:0007254///JNK cascade+++GO:0042228///interleukin-8 biosynthetic process+++GO:0006954///inflammatory response+++GO:0035556///intracellular signal transduction+++GO:0006952///defense response+++GO:0010942///positive regulation of cell death+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","nucleotide binding oligomerization domain containing 1","[NOD1_HUMAN|Reviewed]RecName: Full=Nucleotide-binding oligomerization domain-containing protein 1; AltName: Full=Caspase recruitment domain-containing protein 4;+++[A0A024RA73_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4 {ECO:0000313|EMBL:EAL24453.1}; SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW93949.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 1 {ECO:0000313|EMBL:ALQ33972.1};+++[A0A0S2Z4W5_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 2 {ECO:0000313|EMBL:ALQ33973.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 3 {ECO:0000313|EMBL:ALQ33974.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 4 {ECO:0000313|EMBL:ALQ33975.1};+++[A0A1B0GX71_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000399505}; Flags: Fragment;+++[C9J8X8_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410917}; Flags: Fragment;+++[G3XAL1_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_c {ECO:0000313|EMBL:EAW93948.1}; SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000416946};"]
[10393,"'ANAPC10'",56,56,47,53,"04114///Oocyte meiosis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04111///Cell cycle - yeast+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex","GO:0016887///ATPase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0005506///iron ion binding+++GO:0060698///endoribonuclease inhibitor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding","GO:0007049///cell cycle+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0051301///cell division+++GO:0016567///protein ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition","anaphase promoting complex subunit 10","[APC10_HUMAN|Reviewed]RecName: Full=Anaphase-promoting complex subunit 10; Short=APC10; AltName: Full=Cyclosome subunit 10;+++[A0A286YEY6_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000493135};+++[D6R9Q5_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423223}; Flags: Fragment;+++[D6RA92_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423043}; Flags: Fragment;+++[D6RB36_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000424463}; Flags: Fragment;+++[D6RD74_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000425459};+++[Q4W5I2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein APC10 {ECO:0000313|EMBL:AAY40941.1}; Flags: Fragment;"]
[10395,"'DLC1'",745,564,543,617.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0071682///endocytic vesicle lumen+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0070062///extracellular exosome+++GO:1904724///tertiary granule lumen+++GO:0005615///extracellular space+++GO:0072562///blood microparticle+++GO:0035580///specific granule lumen+++GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0030492///hemoglobin binding+++GO:0016209///antioxidant activity+++GO:0005515///protein binding","GO:0042742///defense response to bacterium+++GO:0002376///immune system process+++GO:0042542///response to hydrogen peroxide+++GO:0006952///defense response+++GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis+++GO:0006953///acute-phase response+++GO:0098869///cellular oxidant detoxification+++GO:0043312///neutrophil degranulation+++GO:2000296///negative regulation of hydrogen peroxide catabolic process+++GO:0002526///acute inflammatory response+++GO:0010033///response to organic substance+++GO:0010942///positive regulation of cell death+++GO:0051354///negative regulation of oxidoreductase activity","DLC1 Rho GTPase activating protein","[RHG07_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 7; AltName: Full=Deleted in liver cancer 1 protein; Short=DLC-1; AltName: Full=HP protein; AltName: Full=Rho-type GTPase-activating protein 7; AltName: Full=START domain-containing protein 12; Short=StARD12; AltName: Full=StAR-related lipid transfer protein 12;+++[A0A087WU08_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000478279};+++[A0A0J9YWS8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000488100}; Flags: Fragment;+++[A0A0U4DJF7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40940.1}; Flags: Fragment;+++[A0A0U4DKQ8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40945.1}; Flags: Fragment;+++[A0A0U4ERW6_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40957.1}; Flags: Fragment;+++[A0A0U4EXB4_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40958.1}; Flags: Fragment;+++[A0A2X0SYX6_HUMAN|Unreviewed]SubName: Full=DLC1 {ECO:0000313|EMBL:SPT35739.1}; Flags: Fragment;+++[A8K119_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76742, highly similar to Homo sapiens deleted in liver cancer 1 (DLC1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF82423.1};+++[E5RI70_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000429537}; Flags: Fragment;+++[H0Y300_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000350406};+++[H3BMJ7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000454413};+++[H3BS21_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000456503}; Flags: Fragment;+++[J3KRH2_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000461999}; Flags: Fragment;+++[J3KSV1_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000462662}; Flags: Fragment;+++[J3QLC9_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463491}; Flags: Fragment;+++[J3QQI8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463755};+++[J3QR68_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000464070}; Flags: Fragment;+++[Q14552_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:AAA52686.1}; Flags: Fragment;+++[Q45XF9_HUMAN|Unreviewed]SubName: Full=Deleted in liver cancer 1 variant 2 {ECO:0000313|EMBL:AAZ32941.1}; Flags: Fragment;+++[Q6NSB4_HUMAN|Unreviewed]SubName: Full=HP protein {ECO:0000313|EMBL:AAH70299.1};+++[R4GMP5_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000473289}; Flags: Fragment;"]
[10396,"'ATP8A1'",83,38,145,88.6666666666667,null,"H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0035579///specific granule membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005802///trans-Golgi network+++GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0042584///chromaffin granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0005524///ATP binding+++GO:0019829///cation-transporting ATPase activity","GO:0030335///positive regulation of cell migration+++GO:0061092///positive regulation of phospholipid translocation+++GO:0034220///ion transmembrane transport+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport+++GO:0007612///learning+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0043312///neutrophil degranulation+++GO:0006869///lipid transport","ATPase phospholipid transporting 8A1","[AT8A1_HUMAN|Reviewed]RecName: Full=Phospholipid-transporting ATPase IA; EC=3.6.3.1; AltName: Full=ATPase class I type 8A member 1; AltName: Full=Chromaffin granule ATPase II; AltName: Full=P4-ATPase flippase complex alpha subunit ATP8A1;+++[H0Y8I6_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000421164}; Flags: Fragment;+++[H0YAA1_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426495}; Flags: Fragment;+++[H0YAF4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426935}; Flags: Fragment;+++[H0YAJ4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000427295}; Flags: Fragment;+++[Q4G1C1_HUMAN|Unreviewed]SubName: Full=ATP8A1 protein {ECO:0000313|EMBL:AAH20943.1}; SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426636};"]
[10397,"'NDRG1'",492,400,672,521.333333333333,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0005815///microtubule organizing center+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton","GO:0017137///Rab GTPase binding+++GO:0043015///gamma-tubulin binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0045576///mast cell activation+++GO:0007165///signal transduction+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0099173///postsynapse organization+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0071456///cellular response to hypoxia+++GO:0042981///regulation of apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010038///response to metal ion+++GO:0042127///regulation of cell proliferation","N-myc downstream regulated 1","[NDRG1_HUMAN|Reviewed]RecName: Full=Protein NDRG1; AltName: Full=Differentiation-related gene 1 protein; Short=DRG-1; AltName: Full=N-myc downstream-regulated gene 1 protein; AltName: Full=Nickel-specific induction protein Cap43; AltName: Full=Reducing agents and tunicamycin-responsive protein; Short=RTP; AltName: Full=Rit42;+++[A0A024R9I3_HUMAN|Unreviewed]SubName: Full=N-myc downstream regulated gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW92166.1};+++[B3KWB2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ42719 fis, clone BRAMY3010492, highly similar to Protein NDRG1 {ECO:0000313|EMBL:BAG54074.1};+++[E5RG99_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428802}; Flags: Fragment;+++[E5RGG6_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000430171}; Flags: Fragment;+++[E5RGM5_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429994}; Flags: Fragment;+++[E5RH82_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429840}; Flags: Fragment;+++[E5RI76_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429524}; Flags: Fragment;+++[E5RIM2_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429380};+++[E5RIR1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428384}; Flags: Fragment;+++[E5RIV1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428345}; Flags: Fragment;+++[E5RJ98_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429172};+++[E5RJY1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000431057};+++[E5RK17_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428991}; Flags: Fragment;+++[E7ESM1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429007};+++[Q8N959_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38330 fis, clone FCBBF3025280, highly similar to NDRG1 PROTEIN {ECO:0000313|EMBL:BAC04597.1};"]
[10398,"'MYL9'",43460,54042,40961,46154.3333333333,"04670///Leukocyte transendothelial migration+++04270///Vascular smooth muscle contraction+++04530///Tight junction+++04921///Oxytocin signaling pathway+++04024///cAMP signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005829///cytosol+++GO:0001725///stress fiber+++GO:0030018///Z disc+++GO:0005859///muscle myosin complex","GO:0046872///metal ion binding+++GO:0008307///structural constituent of muscle+++GO:0032036///myosin heavy chain binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0070527///platelet aggregation","myosin light chain 9","[MYL9_HUMAN|Reviewed]RecName: Full=Myosin regulatory light polypeptide 9; AltName: Full=20 kDa myosin light chain; Short=LC20; AltName: Full=MLC-2C; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 9; AltName: Full=Myosin regulatory light chain MRLC1;+++[Q6IBG1_HUMAN|Unreviewed]SubName: Full=MYL9 protein {ECO:0000313|EMBL:CAG33124.1};"]
[10399,"'RACK1'",18691,19667,19350,19236,"05162///Measles",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005840///ribosome+++GO:1990630///IRE1-RACK1-PP2A complex+++GO:0001891///phagocytic cup+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0015935///small ribosomal subunit+++GO:0042995///cell projection+++GO:0005654///nucleoplasm+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0044297///cell body+++GO:0030496///midbody+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043204///perikaryon+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0045296///cadherin binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0003723///RNA binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0008200///ion channel inhibitor activity+++GO:0030292///protein tyrosine kinase inhibitor activity+++GO:0043022///ribosome binding+++GO:0042169///SH2 domain binding+++GO:0005080///protein kinase C binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0019899///enzyme binding+++GO:0030332///cyclin binding+++GO:0019903///protein phosphatase binding+++GO:0035591///signaling adaptor activity+++GO:0042803///protein homodimerization activity","GO:0072344///rescue of stalled ribosome+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0032464///positive regulation of protein homooligomerization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006412///translation+++GO:0071363///cellular response to growth factor stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:1900102///negative regulation of endoplasmic reticulum unfolded protein response+++GO:0017148///negative regulation of translation+++GO:0032880///regulation of protein localization+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0043065///positive regulation of apoptotic process+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0007369///gastrulation+++GO:0040008///regulation of growth+++GO:0016567///protein ubiquitination+++GO:0030308///negative regulation of cell growth+++GO:0050765///negative regulation of phagocytosis+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0048511///rhythmic process+++GO:0043547///positive regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0006915///apoptotic process+++GO:2000304///positive regulation of ceramide biosynthetic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010629///negative regulation of gene expression+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:0006417///regulation of translation+++GO:2000543///positive regulation of gastrulation+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051726///regulation of cell cycle+++GO:0051302///regulation of cell division+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0043473///pigmentation+++GO:0071333///cellular response to glucose stimulus","receptor for activated C kinase 1","[RACK1_HUMAN|Reviewed]RecName: Full=Receptor of activated protein C kinase 1; AltName: Full=Cell proliferation-inducing gene 21 protein; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1; AltName: Full=Guanine nucleotide-binding protein subunit beta-like protein 12.3; AltName: Full=Human lung cancer oncogene 7 protein; Short=HLC-7; AltName: Full=Receptor for activated C kinase; AltName: Full=Small ribosomal subunit protein RACK1 {ECO:0000303|PubMed:24524803}; Contains: RecName: Full=Receptor of activated protein C kinase 1, N-terminally processed; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed;+++[D6R909_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422198};+++[D6R9L0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000423569}; Flags: Fragment;+++[D6R9Z1_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422029}; Flags: Fragment;+++[D6RAC2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422768};+++[D6RAU2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424760};+++[D6RBD0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424237}; Flags: Fragment;+++[D6RDI0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000420936};+++[D6REE5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000425008}; Flags: Fragment;+++[D6RF23_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426708};+++[D6RFX4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421416}; Flags: Fragment;+++[D6RFZ9_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421356}; Flags: Fragment;+++[D6RGK8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426270};+++[D6RHH4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426101};+++[D6RHJ5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426046};+++[E9KL35_HUMAN|Unreviewed]SubName: Full=Epididymis tissue sperm binding protein Li 3a {ECO:0000313|EMBL:ADU87634.1};+++[E9PD14_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426111};+++[H0Y8R5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421838}; Flags: Fragment;+++[H0Y8W2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422316}; Flags: Fragment;+++[H0Y9P0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424654}; Flags: Fragment;+++[H0YAF8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426960}; Flags: Fragment;+++[H0YAM7_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000427677}; Flags: Fragment;+++[I3QNU9_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein beta polypeptide 2-like 1 {ECO:0000313|EMBL:AFK13122.1}; Flags: Fragment;+++[J3KPE3_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000366013};"]
[104,"'ADARB1'",286,263,287,278.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm","GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003729///mRNA binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0004000///adenosine deaminase activity","GO:0006382///adenosine to inosine editing+++GO:0051726///regulation of cell cycle+++GO:0051607///defense response to virus+++GO:0021610///facial nerve morphogenesis+++GO:0061744///motor behavior+++GO:0050884///neuromuscular process controlling posture+++GO:0030336///negative regulation of cell migration+++GO:0007274///neuromuscular synaptic transmission+++GO:0008285///negative regulation of cell proliferation+++GO:0006396///RNA processing+++GO:0035264///multicellular organism growth+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0097049///motor neuron apoptotic process+++GO:0060384///innervation+++GO:0006397///mRNA processing+++GO:0021618///hypoglossal nerve morphogenesis+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060415///muscle tissue morphogenesis+++GO:0021965///spinal cord ventral commissure morphogenesis+++GO:0045087///innate immune response+++GO:0016553///base conversion or substitution editing","adenosine deaminase, RNA specific B1","[RED1_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific editase 1; EC=3.5.4.37; AltName: Full=RNA-editing deaminase 1; AltName: Full=RNA-editing enzyme 1; AltName: Full=dsRNA adenosine deaminase;+++[A0A0A0MSG8_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000387480}; Flags: Fragment;+++[Q86XN4_HUMAN|Unreviewed]SubName: Full=RNA adenosine deaminase {ECO:0000313|EMBL:AAB18134.1};+++[Q8TCX7_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000478160}; SubName: Full=HCG2008433 {ECO:0000313|EMBL:EAX09362.1};"]
[1040,"'CDS1'",86,79,82,82.3333333333333,"04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,"M00093///Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE","R01799///CTP:phosphatidate cytidyltransferase   CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol","GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0004142///diacylglycerol cholinephosphotransferase activity","GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0007602///phototransduction+++GO:0007165///signal transduction+++GO:0006661///phosphatidylinositol biosynthetic process","CDP-diacylglycerol synthase 1","[CDS1_HUMAN|Reviewed]RecName: Full=Phosphatidate cytidylyltransferase 1; EC=2.7.7.41; AltName: Full=CDP-DAG synthase 1; AltName: Full=CDP-DG synthase 1; AltName: Full=CDP-diacylglycerol synthase 1; Short=CDS 1; AltName: Full=CDP-diglyceride pyrophosphorylase 1; AltName: Full=CDP-diglyceride synthase 1; AltName: Full=CTP:phosphatidate cytidylyltransferase 1;+++[A0A024RDG8_HUMAN|Unreviewed]RecName: Full=Phosphatidate cytidylyltransferase {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938}; EC=2.7.7.41 {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938};"]
[10400,"'PEMT'",527,684,610,607,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites",null,"M00091///Phosphatidylcholine (PC) biosynthesis, PE => PC","R03424///S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine+++R02056///S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine+++R01320///S-adenosyl-L-methionine:phosphatidyl-N-dimethylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidylcholine","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0004603///phenylethanolamine N-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0042423///catecholamine biosynthetic process+++GO:0032259///methylation+++GO:0042418///epinephrine biosynthetic process","phosphatidylethanolamine N-methyltransferase","[PEMT_HUMAN|Reviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000255|HAMAP-Rule:MF_03216}; AltName: Full=PEMT2; AltName: Full=Phospholipid methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000255|HAMAP-Rule:MF_03216};+++[D3YTC7_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};+++[J3KTR2_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463112};+++[J3QLU8_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463713};+++[J3QRI3_HUMAN|Unreviewed]SubName: Full=Phenylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000464234};+++[Q6FHD9_HUMAN|Unreviewed]SubName: Full=PNMT protein {ECO:0000313|EMBL:CAG46614.1};+++[Q71UY0_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};"]
[10401,"'PIAS3'",1019,1077,1252,1116,"04120///Ubiquitin mediated proteolysis+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0030425///dendrite+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0045202///synapse+++GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0015459///potassium channel regulator activity+++GO:0051059///NF-kappaB binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0019789///SUMO transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0047485///protein N-terminus binding","GO:0009725///response to hormone+++GO:0071847///TNFSF11-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010629///negative regulation of gene expression+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0033234///negative regulation of protein sumoylation+++GO:0033235///positive regulation of protein sumoylation+++GO:0045838///positive regulation of membrane potential+++GO:0016925///protein sumoylation","protein inhibitor of activated STAT 3","[PIAS3_HUMAN|Reviewed]RecName: Full=E3 SUMO-protein ligase PIAS3; EC=2.3.2.-; AltName: Full=E3 SUMO-protein transferase PIAS3 {ECO:0000305}; AltName: Full=Protein inhibitor of activated STAT protein 3;+++[B3KNI3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14651 fis, clone NT2RP2002193, highly similar to Protein inhibitor of activated STAT protein 3 {ECO:0000313|EMBL:BAG51345.1};+++[E7ESB4_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000376766}; Flags: Fragment;+++[E9PHH8_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000358304};+++[Q6IAR4_HUMAN|Unreviewed]SubName: Full=PIAS3 protein {ECO:0000313|EMBL:CAG33371.1}; SubName: Full=Protein inhibitor of activated STAT3 {ECO:0000313|EMBL:AAP35684.1};+++[U3KQV1_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000476245}; Flags: Fragment;"]
[10402,"'ST3GAL6'",35,23,33,30.3333333333333,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++01100///Metabolic pathways",null,null,"R06026///CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-3-paragloboside+++R06037///CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI3NeuAc-nLc6Cer","GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0052798///beta-galactoside alpha-2,3-sialyltransferase activity","GO:0006464///cellular protein modification process+++GO:0006486///protein glycosylation+++GO:0071354///cellular response to interleukin-6+++GO:0009311///oligosaccharide metabolic process+++GO:0006664///glycolipid metabolic process+++GO:0009247///glycolipid biosynthetic process+++GO:0097503///sialylation+++GO:0018146///keratan sulfate biosynthetic process","ST3 beta-galactoside alpha-2,3-sialyltransferase 6","[SIA10_HUMAN|Reviewed]RecName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase; EC=2.4.99.-; AltName: Full=CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; AltName: Full=ST3Gal VI; Short=ST3GalVI; AltName: Full=Sialyltransferase 10;+++[A0A087WXB8_HUMAN|Unreviewed]SubName: Full=ST3 beta-galactoside alpha-2,3-sialyltransferase 6, isoform CRA_b {ECO:0000313|EMBL:EAW79851.1}; SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000480884};+++[C9IZL6_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418650}; Flags: Fragment;+++[C9J0E2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418896}; Flags: Fragment;+++[C9J480_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417201}; Flags: Fragment;+++[C9J9Y4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417584}; Flags: Fragment;+++[C9JMW7_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000420474};+++[C9JWI9_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419209}; Flags: Fragment;+++[C9JWJ3_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419202}; Flags: Fragment;+++[C9JXM2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419987}; Flags: Fragment;+++[F2Z2F4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417109};+++[F8WC98_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418581};"]
[10403,"'NDC80'",3,4,4,3.66666666666667,{"$nulls":4},"GO:0005694///chromosome+++GO:0031262///Ndc80 complex+++GO:0005829///cytosol+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005813///centrosome+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000777///condensed chromosome kinetochore","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0051383///kinetochore organization+++GO:1905342///positive regulation of protein localization to kinetochore+++GO:0000070///mitotic sister chromatid segregation+++GO:0000278///mitotic cell cycle+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0007059///chromosome segregation+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0051301///cell division+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0000132///establishment of mitotic spindle orientation","NDC80, kinetochore complex component","[NDC80_HUMAN|Reviewed]RecName: Full=Kinetochore protein NDC80 homolog; AltName: Full=Highly expressed in cancer protein; AltName: Full=Kinetochore protein Hec1; Short=HsHec1; AltName: Full=Kinetochore-associated protein 2; AltName: Full=Retinoblastoma-associated protein HEC;+++[A8K031_HUMAN|Unreviewed]SubName: Full=Kinetochore associated 2, isoform CRA_a {ECO:0000313|EMBL:EAX01696.1}; SubName: Full=NDC80 homolog, kinetochore complex component (S. cerevisiae) {ECO:0000313|EMBL:AAH35617.1}; SubName: Full=cDNA FLJ77925, highly similar to Homo sapiens kinetochore associated 2, mRNA {ECO:0000313|EMBL:BAF82085.1}; SubName: Full=cDNA, FLJ93683, Homo sapiens kinetochore associated 2 (KNTC2), mRNA {ECO:0000313|EMBL:BAG36001.1};+++[I3L0P0_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000458236}; Flags: Fragment;+++[I3L4G3_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000461227}; Flags: Fragment;+++[Q05DQ6_HUMAN|Unreviewed]SubName: Full=NDC80 protein {ECO:0000313|EMBL:AAH05239.1}; Flags: Fragment;+++[V9GYM9_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000476919}; Flags: Fragment;"]
[10404,"'CPQ'",422,425,485,444,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0042803///protein homodimerization activity+++GO:0008233///peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0070573///metallodipeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding","GO:0042246///tissue regeneration+++GO:0043171///peptide catabolic process+++GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation","carboxypeptidase Q","[CBPQ_HUMAN|Reviewed]RecName: Full=Carboxypeptidase Q; EC=3.4.17.-; AltName: Full=Lysosomal dipeptidase; AltName: Full=Plasma glutamate carboxypeptidase; Flags: Precursor;+++[A0A024R9B8_HUMAN|Unreviewed]SubName: Full=Plasma glutamate carboxypeptidase, isoform CRA_a {ECO:0000313|EMBL:EAW91758.1};+++[E5RH35_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429934}; Flags: Fragment;+++[E5RJA8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429146}; Flags: Fragment;+++[E5RJP8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431114}; Flags: Fragment;+++[E5RJZ7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431024}; Flags: Fragment;+++[H0YBB7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429134}; Flags: Fragment;"]
[10406,"'WFDC2'",19,32,74,41.6666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0010466///negative regulation of peptidase activity","WAP four-disulfide core domain 2","[WFDC2_HUMAN|Reviewed]RecName: Full=WAP four-disulfide core domain protein 2; AltName: Full=Epididymal secretory protein E4; AltName: Full=Major epididymis-specific protein E4; AltName: Full=Putative protease inhibitor WAP5; Flags: Precursor;+++[A8K2M3_HUMAN|Unreviewed]SubName: Full=WAP four-disulfide core domain 2, isoform CRA_c {ECO:0000313|EMBL:EAW75838.1}; SubName: Full=WAP four-disulfide core domain protein 2 {ECO:0000313|Ensembl:ENSP00000404760}; SubName: Full=cDNA FLJ76533, highly similar to Homo sapiens WAP four-disulfide core domain 2 (WFDC2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF82977.1};"]
[10408,"'MYCNOS'",0,1,1,0.666666666666667,"05202///Transcriptional misregulation in cancer","H00510///Feingold syndrome+++H00043///Neuroblastoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0031647///regulation of protein stability+++GO:0033673///negative regulation of kinase activity+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation","MYCN opposite strand","[NCYM_HUMAN|Reviewed]RecName: Full=N-cym protein; AltName: Full=N-myc opposite strand;"]
[10409,"'BASP1'",3452,3724,3163,3446.33333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0030426///growth cone+++GO:0031982///vesicle+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome","GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding","GO:0060421///positive regulation of heart growth+++GO:0060539///diaphragm development+++GO:0021762///substantia nigra development+++GO:0072075///metanephric mesenchyme development+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:2001076///positive regulation of metanephric ureteric bud development+++GO:0007356///thorax and anterior abdomen determination+++GO:0060231///mesenchymal to epithelial transition+++GO:0008406///gonad development+++GO:0045892///negative regulation of transcription, DNA-templated","brain abundant membrane attached signal protein 1","[BASP1_HUMAN|Reviewed]RecName: Full=Brain acid soluble protein 1; AltName: Full=22 kDa neuronal tissue-enriched acidic protein; AltName: Full=Neuronal axonal membrane protein NAP-22;+++[U3KQP0_HUMAN|Unreviewed]SubName: Full=Brain acid soluble protein 1 {ECO:0000313|Ensembl:ENSP00000476090}; Flags: Fragment;"]
[1041,"'CDSN'",2,6,3,3.66666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0001533///cornified envelope+++GO:0030057///desmosome+++GO:0005911///cell-cell junction","GO:0042803///protein homodimerization activity","GO:0008544///epidermis development+++GO:0070268///cornification+++GO:0030216///keratinocyte differentiation+++GO:0003336///corneocyte desquamation+++GO:0007155///cell adhesion+++GO:1905716///negative regulation of cornification+++GO:0043589///skin morphogenesis+++GO:0098609///cell-cell adhesion","corneodesmosin","[CDSN_HUMAN|Reviewed]RecName: Full=Corneodesmosin; AltName: Full=S protein; Flags: Precursor;+++[D2IYL2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77254.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:ACZ95707.1};+++[G8JLG2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77255.1}; SubName: Full=Corneodesmosin {ECO:0000313|Ensembl:ENSP00000365465};+++[M1SWB8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77250.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AGG40963.1};+++[Q0EFA5_HUMAN|Unreviewed]SubName: Full=S protein {ECO:0000313|EMBL:BAF31283.1};+++[Q2L6G8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77252.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:BAE78625.1, ECO:0000313|Ensembl:ENSP00000373023};+++[Q7Z559_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94641.1}; Flags: Fragment;+++[Q7Z560_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94640.1}; Flags: Fragment;"]
[10410,"'IFITM3'",3624.98,4697.77,3787.85,4036.86666666667,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0032991///protein-containing complex+++GO:0005768///endosome+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0060337///type I interferon signaling pathway+++GO:0032897///negative regulation of viral transcription+++GO:0002376///immune system process+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0046597///negative regulation of viral entry into host cell+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0006955///immune response+++GO:0009615///response to virus+++GO:0051607///defense response to virus","interferon induced transmembrane protein 3","[IFM3_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 3; AltName: Full=Dispanin subfamily A member 2b; Short=DSPA2b; AltName: Full=Interferon-inducible protein 1-8U;+++[E9PS44_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000432108};+++[H9NKY4_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60318.1};+++[H9NL12_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60346.1};+++[H9NL19_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60353.1};+++[R4GNG9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000473645}; Flags: Fragment;"]
[10411,"'RAPGEF3'",55,43,30,42.6666666666667,"04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04720///Long-term potentiation+++04726///Serotonergic synapse+++04670///Leukocyte transendothelial migration+++04261///Adrenergic signaling in cardiomyocytes+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005902///microvillus+++GO:0030864///cortical actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0030175///filopodium","GO:0005515///protein binding+++GO:0030552///cAMP binding+++GO:0000166///nucleotide binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019904///protein domain specific binding+++GO:0017034///Rap guanyl-nucleotide exchange factor activity","GO:0019933///cAMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0051496///positive regulation of stress fiber assembly+++GO:0007264///small GTPase mediated signal transduction+++GO:0034242///negative regulation of syncytium formation by plasma membrane fusion+++GO:1901985///positive regulation of protein acetylation+++GO:0071320///cellular response to cAMP+++GO:0050796///regulation of insulin secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:0032486///Rap protein signal transduction+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:0061028///establishment of endothelial barrier+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0046827///positive regulation of protein export from nucleus+++GO:0043547///positive regulation of GTPase activity+++GO:0060143///positive regulation of syncytium formation by plasma membrane fusion","Rap guanine nucleotide exchange factor 3","[RPGF3_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 3; AltName: Full=Exchange factor directly activated by cAMP 1; AltName: Full=Exchange protein directly activated by cAMP 1; Short=EPAC 1; AltName: Full=Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; AltName: Full=cAMP-regulated guanine nucleotide exchange factor I; Short=cAMP-GEFI;+++[F8VRX1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448480};+++[F8VVJ6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449905};+++[F8VXK1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448804}; Flags: Fragment;+++[F8W0N0_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000446731}; Flags: Fragment;+++[H0YHS2_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000447691}; Flags: Fragment;+++[H0YIP6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449818}; Flags: Fragment;+++[Q569L6_HUMAN|Unreviewed]SubName: Full=RAPGEF3 protein {ECO:0000313|EMBL:AAH92404.2};+++[Q99777_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAB50216.1}; Flags: Fragment;"]
[10412,"'NSA2'",1248,1260,1108,1205.33333333333,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing","NSA2, ribosome biogenesis homolog","[NSA2_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein NSA2 homolog; AltName: Full=Hairy cell leukemia protein 1; AltName: Full=TGF-beta-inducible nuclear protein 1;+++[A0A0A0MQZ6_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000296802};+++[H0YAI9_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000427266}; Flags: Fragment;+++[Q5J7U2_HUMAN|Unreviewed]SubName: Full=TGF beta-inducible nuclear protein 1 {ECO:0000313|EMBL:EAW95749.1}; SubName: Full=TGF-beta inducible nuclear protein {ECO:0000313|EMBL:AAS00024.1}; SubName: Full=cDNA, FLJ94393, Homo sapiens TGF beta-inducible nuclear protein 1 (TINP1), mRNA {ECO:0000313|EMBL:BAG36522.1};"]
[10413,"'YAP1'",1841,1215,1563,1539.66666666667,"04391///Hippo signaling pathway - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species",null,"M00683///Hippo signaling",null,"GO:0005737///cytoplasm+++GO:0071148///TEAD-1-YAP complex+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071149///TEAD-2-YAP complex","GO:0046982///protein heterodimerization activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0070064///proline-rich region binding+++GO:0033613///activating transcription factor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0008022///protein C-terminus binding+++GO:0003714///transcription corepressor activity","GO:0010468///regulation of gene expression+++GO:0035019///somatic stem cell population maintenance+++GO:0048368///lateral mesoderm development+++GO:0030903///notochord development+++GO:0042127///regulation of cell proliferation+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0001570///vasculogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0048339///paraxial mesoderm development+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0035329///hippo signaling+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000737///negative regulation of stem cell differentiation+++GO:0060242///contact inhibition+++GO:0010837///regulation of keratinocyte proliferation+++GO:0060449///bud elongation involved in lung branching+++GO:0072091///regulation of stem cell proliferation+++GO:0032570///response to progesterone+++GO:0060487///lung epithelial cell differentiation+++GO:0008283///cell proliferation+++GO:0061026///cardiac muscle tissue regeneration+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:1902459///positive regulation of stem cell population maintenance+++GO:0046622///positive regulation of organ growth+++GO:0050767///regulation of neurogenesis+++GO:0003015///heart process+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0003143///embryonic heart tube morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001894///tissue homeostasis+++GO:0008284///positive regulation of cell proliferation+++GO:0071300///cellular response to retinoic acid+++GO:0030216///keratinocyte differentiation+++GO:0050847///progesterone receptor signaling pathway+++GO:0071480///cellular response to gamma radiation+++GO:0065003///protein-containing complex assembly","Yes associated protein 1","[YAP1_HUMAN|Reviewed]RecName: Full=Transcriptional coactivator YAP1; Short=Yes-associated protein 1; AltName: Full=Protein yorkie homolog; AltName: Full=Yes-associated protein YAP65 homolog;+++[A0A024R3E4_HUMAN|Unreviewed]SubName: Full=Yes-associated protein 1, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW67014.1};+++[H0YCI3_HUMAN|Unreviewed]SubName: Full=Transcriptional coactivator YAP1 {ECO:0000313|Ensembl:ENSP00000431626}; Flags: Fragment;+++[K0KVU2_HUMAN|Unreviewed]SubName: Full=Yes-associated protein isoform 9 {ECO:0000313|EMBL:CCI79622.1}; Flags: Fragment;+++[Q86T74_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451O0517 {ECO:0000313|EMBL:CAD89963.1}; Flags: Fragment;"]
[10417,"'SPON2'",841,937,1056,944.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0001530///lipopolysaccharide binding+++GO:0003823///antigen binding","GO:0007411///axon guidance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0002448///mast cell mediated immunity+++GO:0008228///opsonization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0051607///defense response to virus+++GO:0032496///response to lipopolysaccharide+++GO:0007155///cell adhesion+++GO:0043152///induction of bacterial agglutination+++GO:0042742///defense response to bacterium+++GO:0050832///defense response to fungus+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0002376///immune system process","spondin 2","[SPON2_HUMAN|Reviewed]RecName: Full=Spondin-2; AltName: Full=Differentially expressed in cancerous and non-cancerous lung cells 1; Short=DIL-1; AltName: Full=Mindin; Flags: Precursor;+++[A0A1Y8ELY7_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421858}; Flags: Fragment;+++[D6RA41_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000423414}; Flags: Fragment;+++[D6RB12_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000424542}; Flags: Fragment;+++[D6RBY3_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000422516}; Flags: Fragment;+++[D6REX2_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421634}; Flags: Fragment;+++[D6RFY9_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421379}; Flags: Fragment;+++[D6RIH5_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000425871}; Flags: Fragment;"]
[10418,"'SPON1'",3,4,1,2.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region","GO:0005201///extracellular matrix structural constituent+++GO:0050693///LBD domain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:1902993///positive regulation of amyloid precursor protein catabolic process+++GO:0010954///positive regulation of protein processing+++GO:1902430///negative regulation of amyloid-beta formation+++GO:0032092///positive regulation of protein binding","spondin 1","[SPON1_HUMAN|Reviewed]RecName: Full=Spondin-1; AltName: Full=F-spondin; AltName: Full=Vascular smooth muscle cell growth-promoting factor; Flags: Precursor;+++[Q3ZCT3_HUMAN|Unreviewed]SubName: Full=SPON1 protein {ECO:0000313|EMBL:AAH41974.1}; Flags: Fragment;"]
[10419,"'PRMT5'",1064,1197,1114,1125,"04111///Cell cycle - yeast+++04011///MAPK signaling pathway - yeast+++03013///RNA transport",null,null,"R11220///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11218///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0035097///histone methyltransferase complex+++GO:0005737///cytoplasm+++GO:0034709///methylosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0008327///methyl-CpG binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0003714///transcription corepressor activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0044020///histone methyltransferase activity (H4-R3 specific)+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0070888///E-box binding+++GO:0005515///protein binding","GO:0006325///chromatin organization+++GO:1904992///positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0044030///regulation of DNA methylation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0042118///endothelial cell activation+++GO:0000387///spliceosomal snRNP assembly+++GO:0097421///liver regeneration+++GO:0043985///histone H4-R3 methylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0018216///peptidyl-arginine methylation+++GO:0008283///cell proliferation+++GO:0006479///protein methylation+++GO:0045596///negative regulation of cell differentiation+++GO:0048511///rhythmic process+++GO:0006353///DNA-templated transcription, termination+++GO:0032922///circadian regulation of gene expression+++GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0035246///peptidyl-arginine N-methylation+++GO:0032259///methylation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0034969///histone arginine methylation+++GO:0007088///regulation of mitotic nuclear division+++GO:0090161///Golgi ribbon formation","protein arginine methyltransferase 5","[ANM5_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 5; EC=2.1.1.320 {ECO:0000269|PubMed:21081503, ECO:0000269|PubMed:23071334}; AltName: Full=72 kDa ICln-binding protein; AltName: Full=Histone-arginine N-methyltransferase PRMT5; AltName: Full=Jak-binding protein 1; AltName: Full=Shk1 kinase-binding protein 1 homolog; Short=SKB1 homolog; Short=SKB1Hs; Contains: RecName: Full=Protein arginine N-methyltransferase 5, N-terminally processed;+++[B4DV00_HUMAN|Unreviewed]RecName: Full=Protein arginine N-methyltransferase 5 {ECO:0000256|PIRNR:PIRNR015894}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR015894};+++[C9JSX3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000409482}; Flags: Fragment;+++[G3V2F5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450633};+++[G3V2L6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450737}; Flags: Fragment;+++[G3V2X6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450919}; Flags: Fragment;+++[G3V3A3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451127};+++[G3V507_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452102};+++[G3V580_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452218}; Flags: Fragment;+++[G3V5L5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452411}; Flags: Fragment;+++[G3V5T6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452509}; Flags: Fragment;+++[H0YJ77_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450956}; Flags: Fragment;+++[H0YJD3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451245}; Flags: Fragment;+++[H0YJX6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452409}; Flags: Fragment;+++[H0YJY6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452501}; Flags: Fragment;+++[H7BZ44_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000387663}; Flags: Fragment;"]
[10420,"'TESK2'",26,32,25,27.6666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding","GO:0030036///actin cytoskeleton organization+++GO:0048041///focal adhesion assembly+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis","testis associated actin remodelling kinase 2","[TESK2_HUMAN|Reviewed]RecName: Full=Dual specificity testis-specific protein kinase 2; EC=2.7.12.1; AltName: Full=Testicular protein kinase 2;+++[B4DFN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58133, highly similar to Dual specificity testis-specific protein kinase 2 {ECO:0000313|EMBL:BAG57493.1};+++[D3DPZ7_HUMAN|Unreviewed]SubName: Full=Testis-specific kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAX06988.1};"]
[10421,"'CD2BP2'",727,796,627,716.666666666667,"03015///mRNA surveillance pathway",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005682///U5 snRNP+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0010923///negative regulation of phosphatase activity+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0006397///mRNA processing","CD2 cytoplasmic tail binding protein 2","[CD2B2_HUMAN|Reviewed]RecName: Full=CD2 antigen cytoplasmic tail-binding protein 2; Short=CD2 cytoplasmic domain-binding protein 2; Short=CD2 tail-binding protein 2; AltName: Full=U5 snRNP 52K protein; Short=U5-52K;+++[A0A024QZC1_HUMAN|Unreviewed]SubName: Full=CD2 antigen (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW52261.1}; SubName: Full=CD2 binding protein 2 isoform 1 {ECO:0000313|EMBL:ALQ33976.1};+++[A0A0S2Z5J7_HUMAN|Unreviewed]SubName: Full=CD2 binding protein 2 isoform 2 {ECO:0000313|EMBL:ALQ33977.1}; Flags: Fragment;"]
[10422,"'UBAC1'",529,503,405,479,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0016567///protein ubiquitination","UBA domain containing 1","[UBAC1_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated domain-containing protein 1; Short=UBA domain-containing protein 1; AltName: Full=E3 ubiquitin-protein ligase subunit KPC2; AltName: Full=Glialblastoma cell differentiation-related protein 1; AltName: Full=Kip1 ubiquitination-promoting complex protein 2;+++[A0A024R8I2_HUMAN|Unreviewed]SubName: Full=Ubiquitin associated domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW88190.1};+++[A0A140VK64_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 64 {ECO:0000313|EMBL:AEE61201.1};"]
[10423,"'CDIPT'",1738,1975,1861,1858,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00564///Glycerophospholipid metabolism+++00562///Inositol phosphate metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase   CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0019992///diacylglycerol binding+++GO:0043178///alcohol binding+++GO:0030246///carbohydrate binding+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046341///CDP-diacylglycerol metabolic process","CDP-diacylglycerol--inositol 3-phosphatidyltransferase","[CDIPT_HUMAN|Reviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase; EC=2.7.8.11; AltName: Full=Phosphatidylinositol synthase; Short=PI synthase; Short=PtdIns synthase;+++[A8K3L7_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KSW0_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KY94_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000455042}; SubName: Full=cDNA FLJ16129 fis, clone BRACE2039823, highly similar to CDP-diacylglycerol--inositol3-phosphatidyltransferase {ECO:0000313|EMBL:BAG54756.1};+++[H3BTJ7_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457207};+++[H3BUR9_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457766};"]
[10424,"'PGRMC2'",1885,1879,1745,1836.33333333333,{"$nulls":4},"GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0005496///steroid binding+++GO:0003707///steroid hormone receptor activity","GO:0043401///steroid hormone mediated signaling pathway","progesterone receptor membrane component 2","[PGRC2_HUMAN|Reviewed]RecName: Full=Membrane-associated progesterone receptor component 2; AltName: Full=Progesterone membrane-binding protein; AltName: Full=Steroid receptor protein DG6;+++[D3DNX8_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475242}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_a {ECO:0000313|EMBL:EAX05179.1};+++[U3KQ70_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475603}; Flags: Fragment;+++[U3KQM0_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000476010}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_c {ECO:0000313|EMBL:EAX05182.1};"]
[10425,"'ARIH2'",812.06,710.76,739.15,753.99,{"$nulls":4},"GO:0005634///nucleus+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0016740///transferase activity","GO:0016567///protein ubiquitination+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0007275///multicellular organism development+++GO:0070936///protein K48-linked ubiquitination+++GO:0048588///developmental cell growth+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination","ariadne RBR E3 ubiquitin protein ligase 2","[ARI2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase ARIH2; Short=ARI-2; Short=Protein ariadne-2 homolog; EC=2.3.2.31 {ECO:0000269|PubMed:16118314, ECO:0000269|PubMed:17646546, ECO:0000269|PubMed:19340006}; AltName: Full=RING-type E3 ubiquitin transferase ARIH2 {ECO:0000305}; AltName: Full=Triad1 protein {ECO:0000303|PubMed:10422847};+++[C9JAU2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000406063}; Flags: Fragment;+++[C9JBC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000397225}; Flags: Fragment;+++[C9JCL4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000404838}; Flags: Fragment;+++[C9JZ71_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000399788}; Flags: Fragment;+++[F8WCS4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000403845};+++[Q53ET9_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;+++[Q6IBL8_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};"]
[10426,"'TUBGCP3'",211,170,150,177,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005816///spindle pole body+++GO:0000923///equatorial microtubule organizing center+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000930///gamma-tubulin complex+++GO:0008275///gamma-tubulin small complex+++GO:0005827///polar microtubule+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005874///microtubule+++GO:0016020///membrane","GO:0005198///structural molecule activity+++GO:0051011///microtubule minus-end binding+++GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007020///microtubule nucleation+++GO:0051321///meiotic cell cycle+++GO:0090307///mitotic spindle assembly+++GO:0000226///microtubule cytoskeleton organization+++GO:0007338///single fertilization+++GO:0051415///microtubule nucleation by interphase microtubule organizing center+++GO:0031122///cytoplasmic microtubule organization","tubulin gamma complex associated protein 3","[GCP3_HUMAN|Reviewed]RecName: Full=Gamma-tubulin complex component 3; Short=GCP-3; Short=hGCP3; AltName: Full=Gamma-ring complex protein 104 kDa; Short=h104p; Short=hGrip104; AltName: Full=Spindle pole body protein Spc98 homolog; Short=hSpc98;+++[A0A087WU06_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};+++[A0A087WZV5_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX56_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX63_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[B4DYP7_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};"]
[10427,"'SEC24B'",705,573,614,630.666666666667,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0000139///Golgi membrane+++GO:0030127///COPII vesicle coat+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1901301///regulation of cargo loading into COPII-coated vesicle+++GO:0001843///neural tube closure+++GO:0015031///protein transport+++GO:0072358///cardiovascular system development+++GO:0002093///auditory receptor cell morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060425///lung morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006886///intracellular protein transport+++GO:0061156///pulmonary artery morphogenesis+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0021747///cochlear nucleus development+++GO:0035909///aorta morphogenesis+++GO:0016192///vesicle-mediated transport+++GO:0090178///regulation of establishment of planar polarity involved in neural tube closure+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060463///lung lobe morphogenesis","SEC24 homolog B, COPII coat complex component","[SC24B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24B {ECO:0000305}; AltName: Full=SEC24-related protein B;+++[B4DTM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61391, highly similar to Protein transport protein Sec24B {ECO:0000313|EMBL:BAG62038.1};"]
[10428,"'CFDP1'",487,520,501,502.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0005575///cellular_component+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore","GO:0003674///molecular_function","GO:0007275///multicellular organism development+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:0008150///biological_process+++GO:0008360///regulation of cell shape+++GO:0007155///cell adhesion+++GO:0042127///regulation of cell proliferation","craniofacial development protein 1","[CFDP1_HUMAN|Reviewed]RecName: Full=Craniofacial development protein 1; AltName: Full=Bucentaur;+++[A0A087WXQ2_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000481200}; Flags: Fragment;+++[A0A0H5APX3_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91204.1};+++[A0A0H5AUJ9_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91203.1};+++[A0A0H5B9V7_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91205.1};+++[H3BQ17_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000455564}; Flags: Fragment;+++[J3KT89_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000462862}; Flags: Fragment;"]
[1043,"'CD52'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0031225///anchored component of membrane+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0016020///membrane+++GO:0097225///sperm midpiece+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane",null,"GO:0045730///respiratory burst+++GO:0007204///positive regulation of cytosolic calcium ion concentration","CD52 molecule","[CD52_HUMAN|Reviewed]RecName: Full=CAMPATH-1 antigen; AltName: Full=CDw52; AltName: Full=Cambridge pathology 1 antigen; AltName: Full=Epididymal secretory protein E5; AltName: Full=Human epididymis-specific protein 5; Short=He5; AltName: CD_antigen=CD52; Flags: Precursor;+++[Q6IBD0_HUMAN|Unreviewed]SubName: Full=CD52 antigen (CAMPATH-1 antigen) {ECO:0000313|EMBL:EAX07822.1}; SubName: Full=CDW52 antigen (CAMPATH-1 antigen) {ECO:0000313|EMBL:AAP35780.1}; SubName: Full=CDW52 protein {ECO:0000313|EMBL:CAG33155.1};+++[Q9UJ81_HUMAN|Unreviewed]SubName: Full=CD52 protein {ECO:0000313|EMBL:CAB51285.1}; Flags: Fragment;+++[V9HWN9_HUMAN|Unreviewed]SubName: Full=CD52 antigen {ECO:0000313|EMBL:AJC19276.1}; SubName: Full=Epididymis secretory sperm binding protein Li 171mP {ECO:0000313|EMBL:ACS44650.1};"]
[10430,"'TMEM147'",1932,2321,1970,2074.33333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0032991///protein-containing complex","GO:0005515///protein binding",null,"transmembrane protein 147","[TM147_HUMAN|Reviewed]RecName: Full=Transmembrane protein 147; AltName: Full=Protein NIFIE 14;+++[A8MU21_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000376041};+++[K7ELX3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000466262};"]
[10432,"'RBM14'",809.64,870.25,954,877.963333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0003676///nucleic acid binding+++GO:0030674///protein binding, bridging+++GO:0003723///RNA binding+++GO:0003712///transcription coregulator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0002218///activation of innate immune response+++GO:0006281///DNA repair+++GO:0045087///innate immune response+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0006310///DNA recombination+++GO:0016575///histone deacetylation+++GO:0098534///centriole assembly+++GO:0046600///negative regulation of centriole replication+++GO:0002376///immune system process+++GO:0009725///response to hormone+++GO:0042921///glucocorticoid receptor signaling pathway","RNA binding motif protein 14","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0S2Z4Z0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 1 {ECO:0000313|EMBL:ALQ33978.1}; Flags: Fragment;+++[A0A0S2Z567_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 2 {ECO:0000313|EMBL:ALQ33979.1};+++[A0A0S2Z5V2_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 3 {ECO:0000313|EMBL:ALQ33980.1};+++[B8ZZ74_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000386518};+++[F8WDX3_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000414650};"]
[10434,"'LYPLA1'",435,277,335,349,"05231///Choline metabolism in cancer+++00564///Glycerophospholipid metabolism",null,null,"R02746///1-Acyl-sn-glycero-3-phosphocholine acylhydrolase   1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid+++R03416///1-Acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase   1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine","GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0016298///lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0008474///palmitoyl-(protein) hydrolase activity","GO:0042997///negative regulation of Golgi to plasma membrane protein transport+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0006631///fatty acid metabolic process+++GO:0002084///protein depalmitoylation+++GO:0006629///lipid metabolic process","lysophospholipase I","[LYPA1_HUMAN|Reviewed]RecName: Full=Acyl-protein thioesterase 1; Short=APT-1; Short=hAPT1; EC=3.1.2.-; AltName: Full=Lysophospholipase 1; AltName: Full=Lysophospholipase I; Short=LPL-I; Short=LysoPLA I;+++[A0A087X1K9_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000484280};+++[B4DP64_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000482430}; SubName: Full=cDNA FLJ52008, highly similar to Acyl-protein thioesterase 1 {ECO:0000313|EMBL:BAG60476.1};+++[E5RFT6_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000427967};+++[E5RGR0_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428729}; Flags: Fragment;+++[E5RI35_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000430791}; Flags: Fragment;+++[E5RJ48_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428306}; Flags: Fragment;+++[Q6IAQ1_HUMAN|Unreviewed]SubName: Full=LYPLA1 protein {ECO:0000313|EMBL:CAG33384.1}; SubName: Full=Lysophospholipase I, isoform CRA_a {ECO:0000313|EMBL:EAW86742.1}; SubName: Full=cDNA FLJ78542, highly similar to Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAF82089.1}; SubName: Full=cDNA, FLJ94339, Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAG36480.1};"]
[10435,"'CDC42EP2'",339,385,431,385,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0045335///phagocytic vesicle+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017049///GTP-Rho binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0001515///opioid peptide activity","GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity+++GO:0007266///Rho protein signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0008360///regulation of cell shape+++GO:0010469///regulation of signaling receptor activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007015///actin filament organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031274///positive regulation of pseudopodium assembly","CDC42 effector protein 2","[BORG1_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 2; AltName: Full=Binder of Rho GTPases 1;"]
[10436,"'EMG1'",208,222,199,209.666666666667,"03008///Ribosome biogenesis in eukaryotes","H00616///Bowen-Conradi syndrome (BCS)",null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0070037///rRNA (pseudouridine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0019843///rRNA binding+++GO:0016740///transferase activity","GO:0042274///ribosomal small subunit biogenesis+++GO:0042254///ribosome biogenesis+++GO:0001824///blastocyst development+++GO:0017126///nucleologenesis+++GO:0032259///methylation+++GO:0070475///rRNA base methylation+++GO:0006364///rRNA processing","EMG1, N1-specific pseudouridine methyltransferase","[NEP1_HUMAN|Reviewed]RecName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000305|PubMed:20047967}; EC=2.1.1.- {ECO:0000269|PubMed:20047967}; AltName: Full=18S rRNA (pseudouridine(1248)-N1)-methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=18S rRNA Psi1248 methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=Nucleolar protein EMG1 homolog {ECO:0000250|UniProtKB:Q06287}; AltName: Full=Protein C2f {ECO:0000303|PubMed:9074930}; AltName: Full=Ribosome biogenesis protein NEP1 {ECO:0000303|PubMed:20047967};+++[A0A087WVM7_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000479546}; Flags: Fragment;+++[A0A087WWQ2_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000480420}; Flags: Fragment;+++[A0A0U3B3H7_HUMAN|Unreviewed]SubName: Full=EMG1 N1-specific pseudouridine methyl transferase {ECO:0000313|EMBL:ALT07792.1}; Flags: Fragment;+++[B4DP65_HUMAN|Unreviewed]SubName: Full=EMG1 nucleolar protein homolog (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW88694.1}; SubName: Full=cDNA FLJ56921, highly similar to Probable ribosome biogenesis protein NEP1 {ECO:0000313|EMBL:BAG60477.1};+++[V9GYP5_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000476966}; Flags: Fragment;"]
[10437,"'IFI30'",798,1018,841,885.666666666667,"04612///Antigen processing and presentation",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030054///cell junction+++GO:0043202///lysosomal lumen+++GO:0005764///lysosome+++GO:0005576///extracellular region+++GO:0005829///cytosol","GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0016667///oxidoreductase activity, acting on a sulfur group of donors","GO:0055114///oxidation-reduction process+++GO:0002376///immune system process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I","IFI30, lysosomal thiol reductase","[GILT_HUMAN|Reviewed]RecName: Full=Gamma-interferon-inducible lysosomal thiol reductase; EC=1.8.-.- {ECO:0000269|PubMed:10639150, ECO:0000269|PubMed:10852914}; AltName: Full=Gamma-interferon-inducible protein IP-30; AltName: Full=Legumaturain; Flags: Precursor;+++[A0A024R7N7_HUMAN|Unreviewed]SubName: Full=Interferon, gamma-inducible protein 30, isoform CRA_b {ECO:0000313|EMBL:EAW84665.1};+++[M0QZG3_HUMAN|Unreviewed]SubName: Full=Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000313|Ensembl:ENSP00000470527}; Flags: Fragment;+++[Q96P99_HUMAN|Unreviewed]SubName: Full=Interferon gamma-inducible protein 30 {ECO:0000313|EMBL:AAL02170.1}; Flags: Fragment;"]
[10438,"'C1D'",128,110,119,119,"03018///RNA degradation",{"$nulls":3},"GO:0017053///transcriptional repressor complex+++GO:0005769///early endosome+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0098797///plasma membrane protein complex+++GO:0005886///plasma membrane+++GO:0030666///endocytic vesicle membrane+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005905///clathrin-coated pit+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0030136///clathrin-coated vesicle+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex","GO:0044877///protein-containing complex binding+++GO:0003677///DNA binding+++GO:0016964///alpha-2 macroglobulin receptor activity+++GO:0002020///protease binding+++GO:0042954///lipoprotein transporter activity+++GO:0032050///clathrin heavy chain binding+++GO:0038023///signaling receptor activity+++GO:0003714///transcription corepressor activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0030226///apolipoprotein receptor activity+++GO:0005509///calcium ion binding+++GO:0070325///lipoprotein particle receptor binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0034185///apolipoprotein binding","GO:0042157///lipoprotein metabolic process+++GO:0006915///apoptotic process+++GO:0006364///rRNA processing+++GO:0032092///positive regulation of protein binding+++GO:0051222///positive regulation of protein transport+++GO:0008283///cell proliferation+++GO:0032374///regulation of cholesterol transport+++GO:0010942///positive regulation of cell death+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0042953///lipoprotein transport+++GO:0006897///endocytosis+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0010875///positive regulation of cholesterol efflux+++GO:0002265///astrocyte activation involved in immune response+++GO:0006629///lipid metabolic process+++GO:0000460///maturation of 5.8S rRNA+++GO:0035909///aorta morphogenesis+++GO:0043277///apoptotic cell clearance+++GO:0045732///positive regulation of protein catabolic process+++GO:0051246///regulation of protein metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010977///negative regulation of neuron projection development+++GO:0031623///receptor internalization+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905167///positive regulation of lysosomal protein catabolic process+++GO:0032429///regulation of phospholipase A2 activity+++GO:1904646///cellular response to amyloid-beta+++GO:0006898///receptor-mediated endocytosis+++GO:0001523///retinoid metabolic process+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0021987///cerebral cortex development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0045056///transcytosis+++GO:0097242///amyloid-beta clearance+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0006909///phagocytosis+++GO:0032370///positive regulation of lipid transport+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0045807///positive regulation of endocytosis","C1D nuclear receptor corepressor","[C1D_HUMAN|Reviewed]RecName: Full=Nuclear nucleic acid-binding protein C1D; Short=hC1D;+++[H0YJ88_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451012}; Flags: Fragment;+++[H0YJI8_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451622}; Flags: Fragment;+++[J3KPZ4_HUMAN|Unreviewed]SubName: Full=Nuclear nucleic acid-binding protein C1D {ECO:0000313|Ensembl:ENSP00000384304};+++[L0R6J6_HUMAN|Unreviewed]SubName: Full=Alternative protein LRP1 {ECO:0000313|EMBL:CCO13765.1};+++[Q6PJ72_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH21204.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451737};+++[Q7Z7K9_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH52593.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451449};"]
[10439,"'OLFM1'",27,18,24,23,{"$nulls":4},"GO:0045202///synapse+++GO:0043204///perikaryon+++GO:0005615///extracellular space+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0044295///axonal growth cone+++GO:0005623///cell+++GO:0005576///extracellular region","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0030516///regulation of axon extension+++GO:0023041///neuronal signal transduction+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0003190///atrioventricular valve formation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression","olfactomedin 1","[NOE1_HUMAN|Reviewed]RecName: Full=Noelin; AltName: Full=Neuronal olfactomedin-related ER localized protein; AltName: Full=Olfactomedin-1; Flags: Precursor;+++[F5GZQ2_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000444296}; Flags: Fragment;+++[F5H810_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000443806}; Flags: Fragment;+++[F8W870_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000340318}; Flags: Fragment;+++[H0YFB9_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000437906}; Flags: Fragment;+++[Q5VZL8_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360866};+++[Q6IMJ6_HUMAN|Unreviewed]SubName: Full=NOELIN1_V5 {ECO:0000313|EMBL:DAA01549.1}; SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360864};+++[Q6IMJ7_HUMAN|Unreviewed]SubName: Full=NOELIN1_V4 {ECO:0000313|EMBL:DAA01548.1}; SubName: Full=Olfactomedin 1, isoform CRA_d {ECO:0000313|EMBL:EAW88145.1};+++[Q6IMJ8_HUMAN|Unreviewed]SubName: Full=NOELIN1_V1 {ECO:0000313|EMBL:DAA01545.1}; SubName: Full=Olfactomedin 1, isoform CRA_c {ECO:0000313|EMBL:EAW88144.1};+++[Q96BL8_HUMAN|Unreviewed]SubName: Full=OLFM1 protein {ECO:0000313|EMBL:AAH15437.2}; Flags: Fragment;+++[Q9BWJ9_HUMAN|Unreviewed]SubName: Full=Olfactomedin 1 {ECO:0000313|EMBL:AAH00189.1}; SubName: Full=Olfactomedin 1, isoform CRA_b {ECO:0000313|EMBL:EAW88143.1};"]
[1044,"'CDX1'",5,6,16,9,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008327///methyl-CpG binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding","GO:0009887///animal organ morphogenesis+++GO:0014807///regulation of somitogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060349///bone morphogenesis+++GO:0030154///cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009952///anterior/posterior pattern specification+++GO:0007389///pattern specification process+++GO:0007275///multicellular organism development+++GO:0045944///positive regulation of transcription by RNA polymerase II","caudal type homeobox 1","[CDX1_HUMAN|Reviewed]RecName: Full=Homeobox protein CDX-1; AltName: Full=Caudal-type homeobox protein 1;+++[A0A087WTJ6_HUMAN|Unreviewed]SubName: Full=Homeobox protein CDX-1 {ECO:0000313|Ensembl:ENSP00000477928};+++[Q14DX0_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96249.1};+++[Q4VAU3_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96252.2};+++[Q4VAU5_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96250.1};"]
[10440,"'TIMM17A'",352,337,311,333.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex","GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0010954///positive regulation of protein processing+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0071806///protein transmembrane transport+++GO:0006886///intracellular protein transport+++GO:0006626///protein targeting to mitochondrion","translocase of inner mitochondrial membrane 17A","[TI17A_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-A; AltName: Full=Inner membrane preprotein translocase Tim17a;+++[A0A024R9A5_HUMAN|Unreviewed]SubName: Full=Translocase of inner mitochondrial membrane 17 homolog A (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW91385.1};+++[A0PJ74_HUMAN|Unreviewed]SubName: Full=TIMM17A protein {ECO:0000313|EMBL:AAH16817.1}; Flags: Fragment;+++[Q7RU05_HUMAN|Unreviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM17 {ECO:0000256|RuleBase:RU364008};"]
[10443,"'N4BP2L2'",367,288,259,304.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex","GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1902037///negative regulation of hematopoietic stem cell differentiation+++GO:1902035///positive regulation of hematopoietic stem cell proliferation","NEDD4 binding protein 2 like 2","[N42L2_HUMAN|Reviewed]RecName: Full=NEDD4-binding protein 2-like 2; AltName: Full=Phosphonoformate immuno-associated protein 5;+++[A0A024RDV2_HUMAN|Unreviewed]SubName: Full=HCG32190, isoform CRA_b {ECO:0000313|EMBL:EAX08515.1};+++[B4DPY1_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000350104}; SubName: Full=cDNA FLJ55497 {ECO:0000313|EMBL:BAG60743.1};+++[D6R968_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000423362}; Flags: Fragment;+++[Q96KV2_HUMAN|Unreviewed]SubName: Full=92M18.3 (Novel protein) {ECO:0000313|EMBL:CAC94790.1};+++[Q9Y3H6_HUMAN|Unreviewed]SubName: Full=HCG33128, isoform CRA_a {ECO:0000313|EMBL:EAX08509.1};"]
[10444,"'ZER1'",2538,2656,2677,2623.66666666667,{"$nulls":4},"GO:0031462///Cul2-RING ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:0016567///protein ubiquitination","zyg-11 related cell cycle regulator","[ZER1_HUMAN|Reviewed]RecName: Full=Protein zer-1 homolog; AltName: Full=Hzyg; AltName: Full=Zyg-11 homolog B-like protein; AltName: Full=Zyg11b-like protein;+++[A0A024R8B0_HUMAN|Unreviewed]SubName: Full=Zyg-11 homolog B (C. elegans)-like, isoform CRA_b {ECO:0000313|EMBL:EAW87831.1};+++[Q05BR7_HUMAN|Unreviewed]SubName: Full=ZER1 protein {ECO:0000313|EMBL:AAH33884.1}; Flags: Fragment;+++[X6RC68_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000389271}; Flags: Fragment;+++[X6RD87_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000393051}; Flags: Fragment;"]
[10445,"'MCRS1'",782,927,841,850,"05168///Herpes simplex infection",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0044545///NSL complex+++GO:0043204///perikaryon+++GO:0030425///dendrite+++GO:0000123///histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0031011///Ino80 complex+++GO:0005634///nucleus+++GO:0071339///MLL1 complex+++GO:0005730///nucleolus+++GO:0005844///polysome","GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0034046///poly(G) binding+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)+++GO:0010521///telomerase inhibitor activity+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0008266///poly(U) RNA binding+++GO:0005515///protein binding+++GO:0002151///G-quadruplex RNA binding","GO:0006310///DNA recombination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006464///cellular protein modification process+++GO:0043982///histone H4-K8 acetylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043981///histone H4-K5 acetylation+++GO:0051974///negative regulation of telomerase activity+++GO:0016579///protein deubiquitination+++GO:0043984///histone H4-K16 acetylation+++GO:0006281///DNA repair+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:0006325///chromatin organization+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening","microspherule protein 1","[MCRS1_HUMAN|Reviewed]RecName: Full=Microspherule protein 1; AltName: Full=58 kDa microspherule protein; AltName: Full=Cell cycle-regulated factor p78; AltName: Full=INO80 complex subunit J; AltName: Full=MCRS2;+++[A0A024R134_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1, isoform CRA_d {ECO:0000313|EMBL:EAW58079.1};+++[F8VP44_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000450352}; Flags: Fragment;+++[F8VVA6_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000449343}; Flags: Fragment;+++[F8VZC2_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447739};+++[F8W0I9_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447592}; Flags: Fragment;+++[F8W126_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447514}; Flags: Fragment;+++[H0YI67_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448700}; Flags: Fragment;+++[H0YIA0_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448947}; Flags: Fragment;+++[L8E8H6_HUMAN|Unreviewed]SubName: Full=Alternative protein MCRS1 {ECO:0000313|EMBL:CCQ43031.1};"]
[10446,"'LRRN2'",2207,2231,2959,2465.66666666667,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005615///extracellular space","GO:0038023///signaling receptor activity","GO:0007165///signal transduction+++GO:0007155///cell adhesion","leucine rich repeat neuronal 2","[LRRN2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat neuronal protein 2; AltName: Full=Glioma amplified on chromosome 1 protein; AltName: Full=Leucine-rich repeat neuronal protein 5; Flags: Precursor;+++[A0A024R993_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat neuronal 5, isoform CRA_a {ECO:0000313|EMBL:EAW91521.1};"]
[10447,"'FAM3C'",518,453,387,452.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031089///platelet dense granule lumen+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle","GO:0005125///cytokine activity+++GO:0005515///protein binding","GO:0010469///regulation of signaling receptor activity+++GO:0008150///biological_process+++GO:0045721///negative regulation of gluconeogenesis+++GO:0007275///multicellular organism development+++GO:0002576///platelet degranulation","family with sequence similarity 3 member C","[FAM3C_HUMAN|Reviewed]RecName: Full=Protein FAM3C; AltName: Full=Interleukin-like EMT inducer; Flags: Precursor;+++[C9JMN4_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000408636}; Flags: Fragment;+++[C9JP35_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000414940}; Flags: Fragment;"]
[10449,"'ACAA2'",676,666,664,668.666666666667,"01212///Fatty acid metabolism+++01100///Metabolic pathways+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++00280///Valine, leucine and isoleucine degradation+++01130///Biosynthesis of antibiotics+++00062///Fatty acid elongation",null,"M00087///beta-Oxidation+++M00085///Fatty acid biosynthesis, elongation, mitochondria","R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase   Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase   Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase   Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00391///Acyl-CoA:acetyl-CoA C-acyltransferase   Acyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoacyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase   Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase   Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase   Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA   Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA","GO:0005759///mitochondrial matrix+++GO:0016459///myosin complex+++GO:0005739///mitochondrion","GO:0003824///catalytic activity+++GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0003774///motor activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding","GO:0006629///lipid metabolic process+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0071456///cellular response to hypoxia+++GO:0006635///fatty acid beta-oxidation+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","acetyl-CoA acyltransferase 2","[THIM_HUMAN|Reviewed]RecName: Full=3-ketoacyl-CoA thiolase, mitochondrial; EC=2.3.1.16; AltName: Full=Acetyl-CoA acyltransferase; AltName: Full=Beta-ketothiolase; AltName: Full=Mitochondrial 3-oxoacyl-CoA thiolase; AltName: Full=T1;+++[A0A024R269_HUMAN|Unreviewed]SubName: Full=Acetyl-Coenzyme A acyltransferase 2 (Mitochondrial 3-oxoacyl-Coenzyme A thiolase), isoform CRA_d {ECO:0000313|EMBL:EAW62956.1};+++[A0A0B4J2A4_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466015};+++[B3KNP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30111 fis, clone BNGH42000360, highly similar to 3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|EMBL:BAG51410.1};+++[K7EJ68_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465045}; Flags: Fragment;+++[K7EJB1_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465095}; Flags: Fragment;+++[K7EME0_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466466};+++[K7ER88_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000468157}; Flags: Fragment;"]
[10450,"'PPIE'",382,381,362,375,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000974///Prp19 complex+++GO:0034774///secretory granule lumen+++GO:0071013///catalytic step 2 spliceosome+++GO:0005576///extracellular region+++GO:0005681///spliceosomal complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0051082///unfolded protein binding+++GO:0016853///isomerase activity+++GO:0003676///nucleic acid binding+++GO:0016018///cyclosporin A binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008143///poly(A) binding","GO:0006457///protein folding+++GO:0043312///neutrophil degranulation+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0045070///positive regulation of viral genome replication+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0006355///regulation of transcription, DNA-templated","peptidylprolyl isomerase E","[PPIE_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase E; Short=PPIase E; EC=5.2.1.8 {ECO:0000269|PubMed:18258190, ECO:0000269|PubMed:20541251, ECO:0000269|PubMed:20677832, ECO:0000269|PubMed:8977107}; AltName: Full=Cyclophilin E; AltName: Full=Cyclophilin-33 {ECO:0000303|PubMed:8977107}; AltName: Full=Rotamase E;+++[B3KSZ1_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PEQ6_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PIB0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000436689}; Flags: Fragment;+++[E9PK21_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000431714};+++[E9PKY5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[E9PMH0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434989};+++[H0YCV4_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000432396}; Flags: Fragment;+++[H0YE31_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434888}; Flags: Fragment;"]
[10451,"'VAV3'",115,54,67,78.6666666666667,"04670///Leukocyte transendothelial migration+++04664///Fc epsilon RI signaling pathway+++04662///B cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04666///Fc gamma R-mediated phagocytosis+++04062///Chemokine signaling pathway+++04660///T cell receptor signaling pathway+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005096///GTPase activator activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0001525///angiogenesis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0050853///B cell receptor signaling pathway+++GO:0030032///lamellipodium assembly+++GO:0030031///cell projection assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0016477///cell migration+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0043087///regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008361///regulation of cell size+++GO:0009967///positive regulation of signal transduction+++GO:0048013///ephrin receptor signaling pathway+++GO:0006906///vesicle fusion+++GO:0042493///response to drug+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030593///neutrophil chemotaxis+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0030168///platelet activation+++GO:0030890///positive regulation of B cell proliferation+++GO:0007229///integrin-mediated signaling pathway+++GO:0045785///positive regulation of cell adhesion","vav guanine nucleotide exchange factor 3","[VAV3_HUMAN|Reviewed]RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3;+++[A0A2X0U2Q1_HUMAN|Unreviewed]SubName: Full=VAV3 {ECO:0000313|EMBL:SPT35811.1}; Flags: Fragment;+++[E9PMJ5_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000434944};+++[H0YCG7_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000431544}; Flags: Fragment;+++[H0YDG2_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000433559}; Flags: Fragment;"]
[10452,"'TOMM40'",1069,1257,1183,1169.66666666667,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0046930///pore complex+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0005829///cytosol","GO:0008320///protein transmembrane transporter activity+++GO:0015288///porin activity+++GO:0005515///protein binding","GO:0006626///protein targeting to mitochondrion+++GO:0055085///transmembrane transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0006811///ion transport","translocase of outer mitochondrial membrane 40","[TOM40_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM40 homolog; AltName: Full=Protein Haymaker; AltName: Full=Translocase of outer membrane 40 kDa subunit homolog; AltName: Full=p38.5;+++[K7EJ57_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465032}; Flags: Fragment;+++[K7EKG4_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465608}; Flags: Fragment;+++[K7EKG6_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465611}; Flags: Fragment;"]
[10454,"'TAB1'",744,710,791,748.333333333333,"05145///Toxoplasmosis+++05169///Epstein-Barr virus infection+++05168///Herpes simplex infection+++05140///Leishmaniasis+++04620///Toll-like receptor signaling pathway+++04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway+++04380///Osteoclast differentiation",null,"M00686///Toll-like receptor signaling",null,"GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016607///nuclear speck","GO:0003824///catalytic activity+++GO:0008047///enzyme activator activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0019209///kinase activator activity+++GO:0016301///kinase activity+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:0005515///protein binding","GO:0030324///lung development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0001701///in utero embryonic development+++GO:0000185///activation of MAPKKK activity+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0035904///aorta development+++GO:0003279///cardiac septum development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006470///protein dephosphorylation+++GO:0000187///activation of MAPK activity+++GO:0060976///coronary vasculature development+++GO:0016579///protein deubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0003007///heart morphogenesis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0007254///JNK cascade","TGF-beta activated kinase 1 (MAP3K7) binding protein 1","[TAB1_HUMAN|Reviewed]RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; AltName: Full=TGF-beta-activated kinase 1-binding protein 1; Short=TAK1-binding protein 1;+++[A8K6K3_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 7 interacting protein 1, isoform CRA_f {ECO:0000313|EMBL:EAW60330.1}; SubName: Full=cDNA FLJ78598, highly similar to Homo sapiens mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (MAP3K7IP1), transcript variant alpha, mRNA {ECO:0000313|EMBL:BAF84357.1}; SubName: Full=cDNA, FLJ92811, Homo sapiens mitogen-activated protein kinase kinase kinase 7interacting protein 1 (MAP3K7IP1), mRNA {ECO:0000313|EMBL:BAG35363.1};"]
[10455,"'ECI2'",265,245,264,258,"04146///Peroxisome+++00071///Fatty acid degradation",null,null,"R04756///cis,cis-3,6-Dodecadienoyl-CoA delta3-cis-delta2-trans-isomerase   cis,cis-3,6-Dodecadienoyl-CoA <=> trans,cis-Lauro-2,6-dienoyl-CoA","GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005782///peroxisomal matrix","GO:0000062///fatty-acyl-CoA binding+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds+++GO:0003824///catalytic activity+++GO:0005102///signaling receptor binding+++GO:0016853///isomerase activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity","GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0006635///fatty acid beta-oxidation","enoyl-CoA delta isomerase 2","[ECI2_HUMAN|Reviewed]RecName: Full=Enoyl-CoA delta isomerase 2, mitochondrial; EC=5.3.3.8; AltName: Full=DRS-1; AltName: Full=Delta(3),delta(2)-enoyl-CoA isomerase; Short=D3,D2-enoyl-CoA isomerase; AltName: Full=Diazepam-binding inhibitor-related protein 1; Short=DBI-related protein 1; AltName: Full=Dodecenoyl-CoA isomerase; AltName: Full=Hepatocellular carcinoma-associated antigen 88; AltName: Full=Peroxisomal 3,2-trans-enoyl-CoA isomerase; Short=pECI; AltName: Full=Renal carcinoma antigen NY-REN-1; Flags: Precursor;+++[A0A024QZU5_HUMAN|Unreviewed]SubName: Full=Peroxisomal D3,D2-enoyl-CoA isomerase, isoform CRA_a {ECO:0000313|EMBL:EAW55162.1};+++[A0A0C4DGA2_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000420309}; SubName: Full=Testicular secretory protein Li 33 {ECO:0000313|EMBL:AEE61170.1};+++[C9JB63_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417459}; Flags: Fragment;+++[F1LLU7_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417803};+++[F8W6J1_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000369463};+++[F8WAW4_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417170};+++[Q6IBN4_HUMAN|Unreviewed]SubName: Full=PECI protein {ECO:0000313|EMBL:CAG33049.1};"]
[10456,"'HAX1'",655,716,798,723,null,"H00100///Neutropenic disorders",null,null,"GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0000932///P-body+++GO:0016529///sarcoplasmic reticulum+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030027///lamellipodium","GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0019966///interleukin-1 binding","GO:0030854///positive regulation of granulocyte differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0042981///regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling","HCLS1 associated protein X-1","[HAX1_HUMAN|Reviewed]RecName: Full=HCLS1-associated protein X-1; AltName: Full=HS1-associating protein X-1; Short=HAX-1; AltName: Full=HS1-binding protein 1; Short=HSP1BP-1;+++[A0A0S2Z519_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 5 {ECO:0000313|EMBL:ALQ33983.1};+++[A0A0S2Z565_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 3 {ECO:0000313|EMBL:ALQ33982.1}; Flags: Fragment;+++[A0A0S2Z591_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 1 {ECO:0000313|EMBL:ALQ33981.1}; Flags: Fragment;+++[E9PIQ7_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000433951};+++[Q5VYD6_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000394920}; Flags: Fragment;"]
[10457,"'GPNMB'",42940,42661,41065,42222,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0005887///integral component of plasma membrane","GO:0005178///integrin binding+++GO:0045545///syndecan binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042056///chemoattractant activity+++GO:0048018///receptor ligand activity+++GO:0008201///heparin binding+++GO:0031710///neuromedin B receptor binding","GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0030282///bone mineralization+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0050918///positive chemotaxis+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0050482///arachidonic acid secretion+++GO:0001818///negative regulation of cytokine production+++GO:0045765///regulation of angiogenesis+++GO:0050868///negative regulation of T cell activation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0046888///negative regulation of hormone secretion+++GO:0034103///regulation of tissue remodeling+++GO:0008284///positive regulation of cell proliferation+++GO:0010469///regulation of signaling receptor activity+++GO:0042130///negative regulation of T cell proliferation+++GO:0042593///glucose homeostasis+++GO:0046887///positive regulation of hormone secretion+++GO:0008285///negative regulation of cell proliferation+++GO:0001649///osteoblast differentiation+++GO:0030335///positive regulation of cell migration+++GO:1901215///negative regulation of neuron death+++GO:0007267///cell-cell signaling+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007165///signal transduction","glycoprotein nmb","[GPNMB_HUMAN|Reviewed]RecName: Full=Transmembrane glycoprotein NMB; AltName: Full=Hematopoietic growth factor inducible neurokinin-1 type {ECO:0000303|PubMed:12609765}; Flags: Precursor;+++[A0A024RA55_HUMAN|Unreviewed]SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_b {ECO:0000313|EMBL:EAW93784.1};+++[Q8IXJ5_HUMAN|Unreviewed]SubName: Full=Glycoprotein nmb-like protein {ECO:0000313|EMBL:CAD43718.1};+++[Q96F58_HUMAN|Unreviewed]SubName: Full=GPNMB protein {ECO:0000313|EMBL:AAH11595.1}; SubName: Full=Glycoprotein (Transmembrane) nmb {ECO:0000313|EMBL:AAP35737.1}; SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_a {ECO:0000313|EMBL:EAW93781.1}; SubName: Full=Transmembrane glycoprotein NMB {ECO:0000313|Ensembl:ENSP00000386476};"]
[10458,"'BAIAP2'",2354,2423,2783,2520,"04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0099524///postsynaptic cytosol+++GO:0061846///dendritic spine cytoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043197///dendritic spine+++GO:0043025///neuronal cell body+++GO:0097060///synaptic membrane+++GO:0015629///actin cytoskeleton+++GO:0044306///neuron projection terminus+++GO:0042995///cell projection+++GO:0043198///dendritic shaft+++GO:0030175///filopodium+++GO:0001726///ruffle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0098793///presynapse+++GO:0099092///postsynaptic density, intracellular component+++GO:0099523///presynaptic cytosol+++GO:0061845///neuron projection branch point+++GO:0005791///rough endoplasmic reticulum+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0060076///excitatory synapse+++GO:0098794///postsynapse+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0014069///postsynaptic density","GO:0001221///transcription cofactor binding+++GO:0030165///PDZ domain binding+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0070064///proline-rich region binding+++GO:0042802///identical protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0097110///scaffold protein binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding","GO:0010976///positive regulation of neuron projection development+++GO:1905232///cellular response to L-glutamate+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0099564///modification of synaptic structure, modulating synaptic transmission+++GO:0008286///insulin receptor signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0050804///modulation of chemical synaptic transmission+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:0007009///plasma membrane organization+++GO:0007420///brain development+++GO:0030182///neuron differentiation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0016358///dendrite development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0048167///regulation of synaptic plasticity+++GO:0008360///regulation of cell shape+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0051764///actin crosslink formation+++GO:0035418///protein localization to synapse+++GO:0007409///axonogenesis+++GO:0051017///actin filament bundle assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0009617///response to bacterium","BAI1 associated protein 2","[BAIP2_HUMAN|Reviewed]RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2; Short=BAI-associated protein 2; Short=BAI1-associated protein 2; Short=Protein BAP2; AltName: Full=Fas ligand-associated factor 3; Short=FLAF3; AltName: Full=Insulin receptor substrate p53/p58; Short=IRS-58; Short=IRSp53/58; AltName: Full=Insulin receptor substrate protein of 53 kDa; Short=IRSp53; Short=Insulin receptor substrate p53;+++[B4DWA1_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000391837}; SubName: Full=cDNA FLJ55181, highly similar to Brain-specific angiogenesis inhibitor1-associated protein 2 {ECO:0000313|EMBL:BAG62963.1};+++[I3L0M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458202}; Flags: Fragment;+++[I3L0Y9_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458440}; Flags: Fragment;+++[I3L113_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458494}; Flags: Fragment;+++[I3L125_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458522}; Flags: Fragment;+++[I3L1C8_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458735}; Flags: Fragment;+++[I3L2J6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459730};+++[I3L2M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459787}; Flags: Fragment;+++[I3L327_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460131}; Flags: Fragment;+++[I3L3C5_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460344};+++[I3L3C6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460350}; Flags: Fragment;+++[I3L3J7_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460492};+++[I3L4A3_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461101}; Flags: Fragment;+++[I3L4C2_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461144};+++[I3L526_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461736}; Flags: Fragment;"]
[10459,"'MAD2L2'",281,292,297,290,"04110///Cell cycle+++05100///Bacterial invasion of epithelial cells+++04114///Oocyte meiosis+++05131///Shigellosis+++04914///Progesterone-mediated oocyte maturation","H00238///Fanconi anemia","M00293///DNA polymerase zeta complex",null,"GO:0005730///nucleolus+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0016035///zeta DNA polymerase complex+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex","GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0008432///JUN kinase binding+++GO:0005515///protein binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0006281///DNA repair+++GO:0042772///DNA damage response, signal transduction resulting in transcription+++GO:0045830///positive regulation of isotype switching+++GO:0006302///double-strand break repair+++GO:0042177///negative regulation of protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0042276///error-prone translesion synthesis+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007015///actin filament organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:0051301///cell division+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining","mitotic arrest deficient 2 like 2","[MD2L2_HUMAN|Reviewed]RecName: Full=Mitotic spindle assembly checkpoint protein MAD2B; AltName: Full=Mitotic arrest deficient 2-like protein 2; Short=MAD2-like protein 2; AltName: Full=REV7 homolog; Short=hREV7;+++[A0A024R4I4_HUMAN|Unreviewed]SubName: Full=MAD2 mitotic arrest deficient-like 2 (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71698.1};+++[B1AK43_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000411807}; Flags: Fragment;+++[B1AK44_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000365857};+++[B1AK45_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000400982}; Flags: Fragment;"]
[10460,"'TACC3'",72,69,60,67,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0072686///mitotic spindle+++GO:0005819///spindle+++GO:0005815///microtubule organizing center+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005515///protein binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization+++GO:1902850///microtubule cytoskeleton organization involved in mitosis+++GO:0060236///regulation of mitotic spindle organization","transforming acidic coiled-coil containing protein 3","[TACC3_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 3; AltName: Full=ERIC-1;+++[C9JA91_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418095}; Flags: Fragment;+++[C9JWI7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000419210}; Flags: Fragment;+++[E7EMT0_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000415914}; Flags: Fragment;+++[F8WC55_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418727};+++[H0Y8F2_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000420838}; Flags: Fragment;+++[Q8IX09_HUMAN|Unreviewed]SubName: Full=Erythropoietin induced cDNA-1 transcript variant 2 {ECO:0000313|EMBL:AAN76993.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000478580};"]
[10461,"'MERTK'",153,111,130,131.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016028///rhabdomere+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0001750///photoreceptor outer segment","GO:0000166///nucleotide binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0017147///Wnt-protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity","GO:0030154///cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0060068///vagina development+++GO:0032940///secretion by cell+++GO:0030168///platelet activation+++GO:0097350///neutrophil clearance+++GO:0001779///natural killer cell differentiation+++GO:2000107///negative regulation of leukocyte apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0050766///positive regulation of phagocytosis+++GO:0050900///leukocyte migration+++GO:0006909///phagocytosis+++GO:0043277///apoptotic cell clearance+++GO:0009968///negative regulation of signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0007267///cell-cell signaling+++GO:0001818///negative regulation of cytokine production+++GO:0007166///cell surface receptor signaling pathway+++GO:0060041///retina development in camera-type eye+++GO:0016055///Wnt signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0016310///phosphorylation+++GO:0051250///negative regulation of lymphocyte activation+++GO:0018108///peptidyl-tyrosine phosphorylation","MER proto-oncogene, tyrosine kinase","[MERTK_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase Mer; EC=2.7.10.1; AltName: Full=Proto-oncogene c-Mer; AltName: Full=Receptor tyrosine kinase MerTK; Flags: Precursor;+++[A0A087WZQ5_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000482824};+++[E9PD22_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000402129};+++[E9PHX8_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000387277};+++[H7C3L9_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000412660}; Flags: Fragment;+++[Q1RMG3_HUMAN|Unreviewed]SubName: Full=MERTK protein {ECO:0000313|EMBL:AAI14919.1};+++[Q53QW0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAX93144.1}; Flags: Fragment;+++[Q53R53_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAY24213.1}; Flags: Fragment;"]
[10463,"'SLC30A9'",761,620,607,662.666666666667,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008324///cation transmembrane transporter activity+++GO:0016922///nuclear receptor binding","GO:0006289///nucleotide-excision repair+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006812///cation transport+++GO:0006811///ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0006829///zinc ion transport","solute carrier family 30 member 9","[ZNT9_HUMAN|Reviewed]RecName: Full=Zinc transporter 9; Short=ZnT-9; AltName: Full=Human embryonic lung protein {ECO:0000303|PubMed:10409434}; Short=HuEL {ECO:0000303|PubMed:10409434}; AltName: Full=Solute carrier family 30 member 9;+++[A0A024R9W8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 (Zinc transporter), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW92999.1};+++[A0A0S2Z512_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 2 {ECO:0000313|EMBL:ALQ33985.1};+++[A0A0S2Z514_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 1 {ECO:0000313|EMBL:ALQ33984.1}; Flags: Fragment;+++[D6R9M6_HUMAN|Unreviewed]SubName: Full=Zinc transporter 9 {ECO:0000313|Ensembl:ENSP00000423529};"]
[10464,"'PIBF1'",165,140,145,150,"03018///RNA degradation+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00530///Joubert syndrome","M00391///Exosome, eukaryotes",null,"GO:0005815///microtubule organizing center+++GO:0034451///centriolar satellite+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005813///centrosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0005136///interleukin-4 receptor binding","GO:0032733///positive regulation of interleukin-10 production+++GO:1905515///non-motile cilium assembly+++GO:0042976///activation of Janus kinase activity+++GO:0071539///protein localization to centrosome+++GO:0090307///mitotic spindle assembly+++GO:0060271///cilium assembly+++GO:0002376///immune system process+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032815///negative regulation of natural killer cell activation+++GO:0031393///negative regulation of prostaglandin biosynthetic process+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0007080///mitotic metaphase plate congression","progesterone immunomodulatory binding factor 1","[PIBF1_HUMAN|Reviewed]RecName: Full=Progesterone-induced-blocking factor 1; Short=PIBF; AltName: Full=Centrosomal protein of 90 kDa; Short=CEP90 {ECO:0000303|PubMed:21224392};+++[A0A087WUI6_HUMAN|Unreviewed]SubName: Full=Progesterone-induced-blocking factor 1 {ECO:0000313|Ensembl:ENSP00000478697};+++[Q05DN0_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH06009.1}; Flags: Fragment;+++[Q4G0R1_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH41806.1};"]
[10465,"'PPIH'",142,116,114,124,"03040///Spliceosome",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0071001///U4/U6 snRNP+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0051082///unfolded protein binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0065003///protein-containing complex assembly","peptidylprolyl isomerase H","[PPIH_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase H; Short=PPIase H; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Rotamase H; AltName: Full=Small nuclear ribonucleoprotein particle-specific cyclophilin H; Short=CypH; AltName: Full=U-snRNP-associated cyclophilin SnuCyp-20; Short=USA-CYP;+++[A6NM32_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000361629};+++[C9JAN8_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000405493}; Flags: Fragment;+++[C9JQD4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[H0YEL5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH36_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH57_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[10466,"'COG5'",455,371,406,410.666666666667,"04140///Autophagy - animal+++04910///Insulin signaling pathway+++04137///Mitophagy - animal","H00119///Congenital disorders of glycosylation (CDG) type II",null,null,"GO:0017119///Golgi transport complex+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0032588///trans-Golgi network membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport","component of oligomeric golgi complex 5","[COG5_HUMAN|Reviewed]RecName: Full=Conserved oligomeric Golgi complex subunit 5; Short=COG complex subunit 5; AltName: Full=13S Golgi transport complex 90 kDa subunit; Short=GTC-90; AltName: Full=Component of oligomeric Golgi complex 5; AltName: Full=Golgi transport complex 1;+++[U3KQU7_HUMAN|Unreviewed]SubName: Full=Conserved oligomeric Golgi complex subunit 5 {ECO:0000313|Ensembl:ENSP00000476238}; Flags: Fragment;"]
[10467,"'ZNHIT1'",1526,1701,1525,1584,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000812///Swr1 complex","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding","GO:0006338///chromatin remodeling+++GO:0031063///regulation of histone deacetylation+++GO:0043486///histone exchange","zinc finger HIT-type containing 1","[ZNHI1_HUMAN|Reviewed]RecName: Full=Zinc finger HIT domain-containing protein 1; AltName: Full=Cyclin-G1-binding protein 1; AltName: Full=Zinc finger protein subfamily 4A member 1; AltName: Full=p18 Hamlet;"]
[10468,"'FST'",183,165,130,159.333333333333,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048185///activin binding+++GO:0038102///activin receptor antagonist activity","GO:0051798///positive regulation of hair follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032926///negative regulation of activin receptor signaling pathway","follistatin","[FST_HUMAN|Reviewed]RecName: Full=Follistatin; Short=FS; AltName: Full=Activin-binding protein; Flags: Precursor;+++[A0A024QZU6_HUMAN|Unreviewed]SubName: Full=Follistatin, isoform CRA_c {ECO:0000313|EMBL:EAW54883.1};+++[H0YA75_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426315}; Flags: Fragment;+++[H0YAF9_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426971}; Flags: Fragment;+++[Q6FHE1_HUMAN|Unreviewed]SubName: Full=FST protein {ECO:0000313|EMBL:CAG46612.1};"]
[10469,"'TIMM44'",464,494,463,473.666666666667,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0051087///chaperone binding","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix","translocase of inner mitochondrial membrane 44","[TIM44_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM44; Flags: Precursor;+++[M0QXM9_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469273}; Flags: Fragment;+++[M0QXU7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469389}; Flags: Fragment;+++[M0R124_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000471596};+++[M0R301_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000472916}; Flags: Fragment;"]
[1047,"'CLGN'",3974,3253,3837,3688,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005509///calcium ion binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0007338///single fertilization+++GO:0065003///protein-containing complex assembly+++GO:0007339///binding of sperm to zona pellucida","calmegin","[CLGN_HUMAN|Reviewed]RecName: Full=Calmegin; Flags: Precursor;+++[A0A140VKG2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 79P {ECO:0000313|EMBL:AEE61299.1};"]
[10471,"'PFDN6'",200,256,220,225.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016272///prefoldin complex","GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","prefoldin subunit 6","[PFD6_HUMAN|Reviewed]RecName: Full=Prefoldin subunit 6; AltName: Full=Protein Ke2;+++[A2AB88_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6 {ECO:0000313|Ensembl:ENSP00000420135};+++[I7HJT1_HUMAN|Unreviewed]SubName: Full=HLA class II region expressed gene KE2 {ECO:0000313|EMBL:CAC88187.1}; SubName: Full=Prefoldin subunit 6, isoform CRA_a {ECO:0000313|EMBL:EAX03705.1};+++[Q5STK2_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6, isoform CRA_b {ECO:0000313|EMBL:EAX03706.1}; SubName: Full=cDNA, FLJ92435, Homo sapiens HLA class II region expressed gene KE2 (HKE2), mRNA {ECO:0000313|EMBL:BAG35084.1};"]
[10472,"'ZBTB18'",610,454,558,540.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0000228///nuclear chromosome","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0007275///multicellular organism development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 18","[ZBT18_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 18; AltName: Full=58 kDa repressor protein; AltName: Full=Transcriptional repressor RP58; AltName: Full=Translin-associated zinc finger protein 1; Short=TAZ-1; AltName: Full=Zinc finger protein 238; AltName: Full=Zinc finger protein C2H2-171;+++[A0A024R5T6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 238, isoform CRA_a {ECO:0000313|EMBL:EAW77099.1};"]
[10473,"'HMGN4'",231,253,300,261.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0000785///chromatin","GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding",null,"high mobility group nucleosomal binding domain 4","[HMGN4_HUMAN|Reviewed]RecName: Full=High mobility group nucleosome-binding domain-containing protein 4; AltName: Full=Non-histone chromosomal protein HMG-17-like 3; Short=Non-histone chromosomal protein;+++[A0A024R046_HUMAN|Unreviewed]SubName: Full=High mobility group nucleosomal binding domain 4, isoform CRA_a {ECO:0000313|EMBL:EAW55589.1};"]
[10474,"'TADA3'",3124.98,3293.39,2924.31,3114.22666666667,"05165///Human papillomavirus infection",{"$nulls":3},"GO:0000124///SAGA complex+++GO:0005622///intracellular+++GO:0030914///STAGA complex+++GO:0072686///mitotic spindle+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0033276///transcription factor TFTC complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0016922///nuclear receptor binding+++GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0019904///protein domain specific binding","GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090043///regulation of tubulin deacetylation+++GO:0000278///mitotic cell cycle+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043967///histone H4 acetylation+++GO:0010628///positive regulation of gene expression+++GO:0016579///protein deubiquitination+++GO:0031063///regulation of histone deacetylation+++GO:0001932///regulation of protein phosphorylation+++GO:0031647///regulation of protein stability+++GO:0030520///intracellular estrogen receptor signaling pathway","transcriptional adaptor 3","[TADA3_HUMAN|Reviewed]RecName: Full=Transcriptional adapter 3; AltName: Full=ADA3 homolog; Short=hADA3; AltName: Full=STAF54; AltName: Full=Transcriptional adapter 3-like; Short=ADA3-like protein;+++[A0A024R2D7_HUMAN|Unreviewed]SubName: Full=Transcriptional adaptor 3 (NGG1 homolog, yeast)-like, isoform CRA_a {ECO:0000313|EMBL:EAW63997.1};+++[A8K899_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77724, highly similar to Homo sapiens transcriptional adaptor 3 (NGG1 homolog, yeast)-like (TADA3L), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84953.1};+++[C9JMS0_HUMAN|Unreviewed]SubName: Full=Transcriptional adapter 3 {ECO:0000313|Ensembl:ENSP00000395073}; Flags: Fragment;"]
[10475,"'TRIM38'",332,283,311,308.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050687///negative regulation of defense response to virus+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0046598///positive regulation of viral entry into host cell+++GO:0032648///regulation of interferon-beta production+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0070936///protein K48-linked ubiquitination+++GO:0045087///innate immune response+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","tripartite motif containing 38","[TRI38_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM38; EC=2.3.2.27; AltName: Full=RING finger protein 15; AltName: Full=RING-type E3 ubiquitin transferase TRIM38 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 38; AltName: Full=Zinc finger protein RoRet;+++[A0A024QZY4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 38, isoform CRA_a {ECO:0000313|EMBL:EAW55505.1};"]
[10476,"'ATP5PD'",924,1077,956,985.666666666667,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++05016///Huntington's disease+++05010///Alzheimer's disease+++05012///Parkinson's disease+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0000274///mitochondrial proton-transporting ATP synthase, stator stalk+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005654///nucleoplasm+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005743///mitochondrial inner membrane","GO:0022857///transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0015078///proton transmembrane transporter activity","GO:0015986///ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0006811///ion transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0006754///ATP biosynthetic process+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport","ATP synthase peripheral stalk subunit d","[ATP5H_HUMAN|Reviewed]RecName: Full=ATP synthase subunit d, mitochondrial {ECO:0000305}; Short=ATPase subunit d; AltName: Full=ATP synthase peripheral stalk subunit d {ECO:0000305};+++[A0PJH2_HUMAN|Unreviewed]SubName: Full=ATP5H protein {ECO:0000313|EMBL:AAH29392.1}; Flags: Fragment;+++[F5H608_HUMAN|Unreviewed]SubName: Full=ATP synthase peripheral stalk subunit d {ECO:0000313|Ensembl:ENSP00000437996};+++[L8E9E1_HUMAN|Unreviewed]SubName: Full=Alternative protein ATP5H {ECO:0000313|EMBL:CCQ43351.1};"]
[10477,"'UBE2E3'",678,544,709,643.666666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0070979///protein K11-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0040008///regulation of growth+++GO:0070936///protein K48-linked ubiquitination","ubiquitin conjugating enzyme E2 E3","[UB2E3_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 E3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme E3; AltName: Full=UbcH9; AltName: Full=Ubiquitin carrier protein E3; AltName: Full=Ubiquitin-conjugating enzyme E2-23 kDa; AltName: Full=Ubiquitin-protein ligase E3;+++[A0A1B0GX65_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473525}; Flags: Fragment;+++[R4GMM6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473264};+++[R4GN77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473521}; Flags: Fragment;+++[R4GND1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473591};+++[R4GNG6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473642};"]
[10478,"'SLC25A17'",196,172,219,195.666666666667,"04146///Peroxisome",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005779///integral component of peroxisomal membrane+++GO:0005778///peroxisomal membrane+++GO:0016021///integral component of membrane+++GO:0005777///peroxisome+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane","GO:0015228///coenzyme A transmembrane transporter activity+++GO:0000295///adenine nucleotide transmembrane transporter activity+++GO:0015230///FAD transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0080122///AMP transmembrane transporter activity+++GO:0005347///ATP transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051087///chaperone binding+++GO:0044610///FMN transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity+++GO:0051724///NAD transmembrane transporter activity","GO:0080121///AMP transport+++GO:0035349///coenzyme A transmembrane transport+++GO:0006635///fatty acid beta-oxidation+++GO:0001561///fatty acid alpha-oxidation+++GO:0015908///fatty acid transport+++GO:0015867///ATP transport+++GO:0015866///ADP transport+++GO:0051182///coenzyme transport+++GO:0035352///NAD transmembrane transport+++GO:0035350///FAD transmembrane transport+++GO:0055085///transmembrane transport+++GO:1901679///nucleotide transmembrane transport","solute carrier family 25 member 17","[PM34_HUMAN|Reviewed]RecName: Full=Peroxisomal membrane protein PMP34; AltName: Full=34 kDa peroxisomal membrane protein; AltName: Full=Solute carrier family 25 member 17;+++[B0QYW5_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000385303};+++[B1AHN4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000404200}; Flags: Fragment;+++[B4DP73_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57410, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG60485.1};+++[B4DU97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57596, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG62259.1};+++[F2Z2I9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000410565};+++[F6RTR7_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000438355};+++[F8WA85_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000263255};+++[F8WBA4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000390502};+++[F8WCH6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000400053};+++[F8WCN9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000416618};+++[F8WE74_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000394539};+++[F8WEC6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000388966};+++[F8WF87_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000407096};"]
[10479,"'SLC9A6'",307,209,259,258.333333333333,null,"H01914///Christianson syndrome",null,null,"GO:0043679///axon terminus+++GO:0030425///dendrite+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0031901///early endosome membrane+++GO:0044308///axonal spine+++GO:0005770///late endosome+++GO:0005789///endoplasmic reticulum membrane","GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity","GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0050808///synapse organization+++GO:0098719///sodium ion import across plasma membrane+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway+++GO:0060996///dendritic spine development+++GO:0048675///axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0051453///regulation of intracellular pH+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0097484///dendrite extension","solute carrier family 9 member A6","[SL9A6_HUMAN|Reviewed]RecName: Full=Sodium/hydrogen exchanger 6; AltName: Full=Na(+)/H(+) exchanger 6; Short=NHE-6; AltName: Full=Solute carrier family 9 member 6;+++[A0A1B0GV11_HUMAN|Unreviewed]RecName: Full=Sodium/hydrogen exchanger {ECO:0000256|RuleBase:RU003722};"]
[1048,"'CEACAM5'",1,2,2,1.66666666666667,{"$nulls":4},"GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0071575///integral component of external side of plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0031225///anchored component of membrane+++GO:0016324///apical plasma membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity+++GO:0034235///GPI anchor binding+++GO:0042802///identical protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034109///homotypic cell-cell adhesion+++GO:0010832///negative regulation of myotube differentiation+++GO:2000811///negative regulation of anoikis+++GO:0050900///leukocyte migration","carcinoembryonic antigen related cell adhesion molecule 5","[CEAM5_HUMAN|Reviewed]RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5; AltName: Full=Carcinoembryonic antigen; Short=CEA; AltName: Full=Meconium antigen 100; AltName: CD_antigen=CD66e; Flags: Precursor;+++[A0A024R0K5_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5, isoform CRA_a {ECO:0000313|EMBL:EAW57060.1};+++[A0A087WYX0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000482157};+++[M0QX98_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000468997}; Flags: Fragment;+++[M0R3J1_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000473252}; Flags: Fragment;+++[Q53G30_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 variant {ECO:0000313|EMBL:BAD96821.1}; Flags: Fragment;+++[Q8N4D0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|EMBL:AAH34671.1};+++[T2HUW8_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 3D {ECO:0000313|EMBL:BAN83790.1};+++[T2HVB7_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 5D {ECO:0000313|EMBL:BAN83789.1};"]
[10480,"'EIF3M'",1174,1131,1099,1134.66666666667,{"$nulls":4},"GO:0033290///eukaryotic 48S preinitiation complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0031369///translation initiation factor binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006412///translation+++GO:0006413///translational initiation+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation","eukaryotic translation initiation factor 3 subunit M","[EIF3M_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000255|HAMAP-Rule:MF_03012}; Short=eIF3m {ECO:0000255|HAMAP-Rule:MF_03012}; AltName: Full=Fetal lung protein B5; Short=hFL-B5; AltName: Full=PCI domain-containing protein 1;+++[E7ESM3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435501};+++[E9PN86_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432891}; Flags: Fragment;+++[E9PRI2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432286};+++[E9PRY0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000434080};+++[E9PSB3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435834};+++[H0YCQ8_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432139}; Flags: Fragment;+++[J3KNJ2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000319910}; Flags: Fragment;"]
[10482,"'NXF1'",1143,1073,1107,1107.66666666667,"05168///Herpes simplex infection+++03013///RNA transport+++03015///mRNA surveillance pathway+++05164///Influenza A+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0000346///transcription export complex+++GO:0042405///nuclear inclusion body+++GO:0005737///cytoplasm+++GO:0005643///nuclear pore+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding","GO:0051028///mRNA transport+++GO:0016032///viral process+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus","nuclear RNA export factor 1","[NXF1_HUMAN|Reviewed]RecName: Full=Nuclear RNA export factor 1; AltName: Full=Tip-associated protein; AltName: Full=Tip-associating protein; AltName: Full=mRNA export factor TAP;+++[A0A024R5A9_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW74104.1};+++[B4E227_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61053, highly similar to Nuclear RNA export factor 1 {ECO:0000313|EMBL:BAG64989.1};+++[E9PIN3_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000435742}; Flags: Fragment;+++[E9PLA7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000431381}; Flags: Fragment;+++[E9PMV7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000437296}; Flags: Fragment;+++[E9PQA4_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000432530};+++[H0YDU0_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000434301}; Flags: Fragment;+++[Q59E96_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 variant {ECO:0000313|EMBL:BAD93152.1}; Flags: Fragment;"]
[10483,"'SEC23B'",902,809,930,880.333333333333,"04141///Protein processing in endoplasmic reticulum","H01105///Cranio-lenticulo-sutural dysplasia (CLSD)+++H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)","M00404///COPII complex",null,"GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0012505///endomembrane system+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0008360///regulation of cell shape+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090114///COPII-coated vesicle budding+++GO:0003400///regulation of COPII vesicle coating","Sec23 homolog B, coat complex II component","[SC23B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23B {ECO:0000305}; Short=hSec23B {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein B;+++[A0A2R8Y633_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8Y7S7_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YF30_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YFH5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[Q5QPE1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[Q5QPE2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;"]
[10484,"'SEC23A'",2039,1517,1640,1732,"04141///Protein processing in endoplasmic reticulum","H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)+++H01105///Cranio-lenticulo-sutural dysplasia (CLSD)","M00404///COPII complex",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030127///COPII vesicle coat+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0019898///extrinsic component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0070971///endoplasmic reticulum exit site","GO:0005096///GTPase activator activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0090114///COPII-coated vesicle budding+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0015031///protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0003400///regulation of COPII vesicle coating+++GO:0008360///regulation of cell shape+++GO:0007030///Golgi organization+++GO:0006886///intracellular protein transport+++GO:0048208///COPII vesicle coating+++GO:0043547///positive regulation of GTPase activity","Sec23 homolog A, coat complex II component","[SC23A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23A {ECO:0000305}; Short=hSec23A {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein A;+++[F5H365_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V1W4_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V2R6_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V3G5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V4Q2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V4V1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5K1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5X8_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[L8ECD0_HUMAN|Unreviewed]SubName: Full=Alternative protein SEC23A {ECO:0000313|EMBL:CCQ43352.1};"]
[10485,"'C1orf61'",13,3,7,7.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003674///molecular_function","GO:0045944///positive regulation of transcription by RNA polymerase II","chromosome 1 open reading frame 61","[CROC4_HUMAN|Reviewed]RecName: Full=Protein CROC-4; AltName: Full=Contingent replication of cDNA 4;+++[H0Y3T1_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000383776}; Flags: Fragment;+++[H3BLW3_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000357225}; Flags: Fragment;+++[Q6PB34_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH59943.1}; Flags: Fragment;+++[Q86W69_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH50448.1}; SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000310651}; Flags: Fragment;+++[X6R5L4_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000350661}; Flags: Fragment;"]
[10486,"'CAP2'",2377,2108,2230,2238.33333333333,"04137///Mitophagy - animal+++03010///Ribosome+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly","M00177///Ribosome, eukaryotes",null,"GO:0005886///plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:1990904///ribonucleoprotein complex","GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008179///adenylate cyclase binding+++GO:0042803///protein homodimerization activity+++GO:0003779///actin binding+++GO:0042802///identical protein binding","GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0007190///activation of adenylate cyclase activity+++GO:0002181///cytoplasmic translation+++GO:0007163///establishment or maintenance of cell polarity+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0006364///rRNA processing+++GO:0008154///actin polymerization or depolymerization+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0007165///signal transduction+++GO:0000902///cell morphogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","cyclase associated actin cytoskeleton regulatory protein 2","[CAP2_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 2; Short=CAP 2;+++[A0A087WZ15_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[A0A087X0J3_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[B7Z385_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[E9PDI2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[F8WDB9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000420615};+++[F8WEW0_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000419906};+++[Q5JPJ8_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};"]
[10487,"'CAP1'",7672,7497,6408,7192.33333333333,"01100///Metabolic pathways+++04142///Lysosome+++01212///Fatty acid metabolism+++00062///Fatty acid elongation","H00149///Neuronal ceroid lipofuscinosis (NCL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,"R01274///palmitoyl-CoA hydrolase Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid","GO:0035578///azurophil granule lumen+++GO:0030424///axon+++GO:0005764///lysosome+++GO:0030425///dendrite+++GO:0045121///membrane raft+++GO:0005794///Golgi apparatus+++GO:0030864///cortical actin cytoskeleton+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0043025///neuronal cell body+++GO:0043202///lysosomal lumen+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0008179///adenylate cyclase binding+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0003779///actin binding","GO:0030163///protein catabolic process+++GO:0007269///neurotransmitter secretion+++GO:0006898///receptor-mediated endocytosis+++GO:0007042///lysosomal lumen acidification+++GO:0001667///ameboidal-type cell migration+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0008154///actin polymerization or depolymerization+++GO:0007420///brain development+++GO:0030149///sphingolipid catabolic process+++GO:0007601///visual perception+++GO:0007190///activation of adenylate cyclase activity+++GO:0051186///cofactor metabolic process+++GO:0016042///lipid catabolic process+++GO:0046949///fatty-acyl-CoA biosynthetic process+++GO:0043312///neutrophil degranulation+++GO:0051181///cofactor transport+++GO:0050803///regulation of synapse structure or activity+++GO:0002084///protein depalmitoylation+++GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0007268///chemical synaptic transmission+++GO:0006907///pinocytosis+++GO:0050896///response to stimulus+++GO:0048666///neuron development+++GO:0000902///cell morphogenesis+++GO:0007165///signal transduction+++GO:0032429///regulation of phospholipase A2 activity+++GO:0007625///grooming behavior+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048549///positive regulation of pinocytosis+++GO:0044257///cellular protein catabolic process+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0031579///membrane raft organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0030308///negative regulation of cell growth+++GO:0043066///negative regulation of apoptotic process","cyclase associated actin cytoskeleton regulatory protein 1","[CAP1_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 1; Short=CAP 1;+++[D3DPU2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[L8EAI0_HUMAN|Unreviewed]SubName: Full=Alternative protein CAP1 {ECO:0000313|EMBL:CCQ43353.1};+++[Q5T0R1_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413656}; Flags: Fragment;+++[Q5T0R2_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408561}; Flags: Fragment;+++[Q5T0R3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000403198}; Flags: Fragment;+++[Q5T0R4_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413383}; Flags: Fragment;+++[Q5T0R5_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000410586}; Flags: Fragment;+++[Q5T0R6_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000400943}; Flags: Fragment;+++[Q5T0R7_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398475}; Flags: Fragment;+++[Q5T0R8_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000389974}; Flags: Fragment;+++[Q5T0R9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000412859}; Flags: Fragment;+++[Q5T0S3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398877}; Flags: Fragment;"]
[10488,"'CREB3'",1864,1909,1730,1834.33333333333,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05163///Human cytomegalovirus infection+++04668///TNF signaling pathway+++04714///Thermogenesis+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++04922///Glucagon signaling pathway+++04911///Insulin secretion+++04962///Vasopressin-regulated water reabsorption+++05215///Prostate cancer+++05034///Alcoholism+++05030///Cocaine addiction+++04928///Parathyroid hormone synthesis, secretion and action+++05031///Amphetamine addiction+++04024///cAMP signaling pathway+++04926///Relaxin signaling pathway+++04725///Cholinergic synapse+++04927///Cortisol synthesis and secretion+++05016///Huntington's disease+++05203///Viral carcinogenesis+++04925///Aldosterone synthesis and secretion+++04022///cGMP-PKG signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04211///Longevity regulating pathway+++05165///Human papillomavirus infection+++04934///Cushing's syndrome+++05161///Hepatitis B+++04916///Melanogenesis+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0008140///cAMP response element binding protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:0003682///chromatin binding+++GO:0031726///CCR1 chemokine receptor binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000982///transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0019043///establishment of viral latency+++GO:0001558///regulation of cell growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0051928///positive regulation of calcium ion transport+++GO:0042981///regulation of apoptotic process+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090045///positive regulation of deacetylase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000326///negative regulation of nuclear receptor transcription coactivator activity+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0006990///positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0006351///transcription, DNA-templated+++GO:0019046///release from viral latency+++GO:0016032///viral process+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006935///chemotaxis+++GO:0050930///induction of positive chemotaxis","cAMP responsive element binding protein 3","[CREB3_HUMAN|Reviewed]RecName: Full=Cyclic AMP-responsive element-binding protein 3; Short=CREB-3; Short=cAMP-responsive element-binding protein 3; AltName: Full=Leucine zipper protein; AltName: Full=Luman; AltName: Full=Transcription factor LZIP-alpha; Contains: RecName: Full=Processed cyclic AMP-responsive element-binding protein 3; Short=N-terminal Luman; Short=Transcriptionally active form;"]
[10489,"'LRRC41'",1275,1444,1433,1384,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity","GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination","leucine rich repeat containing 41","[LRC41_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 41; AltName: Full=Protein Muf1;+++[A0A087WTI9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000477909}; Flags: Fragment;+++[A0A087WTU1_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000478135};+++[A0A087X0S7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000483633};+++[A0A0B4J2G4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484752};+++[A0A0C4DH00_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484558};+++[Q562F1_HUMAN|Unreviewed]SubName: Full=LRRC41 protein {ECO:0000313|EMBL:AAH92479.1}; Flags: Fragment;"]
[10490,"'VTI1B'",971,970,932,957.666666666667,"04138///Autophagy - yeast+++04130///SNARE interactions in vesicular transport","H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00186///Hyperargininemia","M00029///Urea cycle+++M00134///Polyamine biosynthesis, arginine => ornithine => putrescine","R00551///L-Arginine amidinohydrolase L-Arginine + H2O <=> L-Ornithine + Urea","GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031093///platelet alpha granule lumen+++GO:0005829///cytosol+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043025///neuronal cell body+++GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0055037///recycling endosome+++GO:0005764///lysosome+++GO:0031901///early endosome membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0031201///SNARE complex+++GO:0005576///extracellular region+++GO:0008021///synaptic vesicle","GO:0005484///SNAP receptor activity+++GO:0019869///chloride channel inhibitor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0002576///platelet degranulation+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006623///protein targeting to vacuole+++GO:0006896///Golgi to vacuole transport+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0008283///cell proliferation+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0097352///autophagosome maturation","vesicle transport through interaction with t-SNAREs 1B","[VTI1B_HUMAN|Reviewed]RecName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B; AltName: Full=Vesicle transport v-SNARE protein Vti1-like 1; AltName: Full=Vti1-rp1;+++[G3V5I2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000452366};+++[H0YJJ5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451661}; Flags: Fragment;+++[H0YJL5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451759}; Flags: Fragment;+++[J3KMW2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000216456};"]
[104909134,"'LINC02210-CRHR1'",57,34,53,48,{"$nulls":4},"GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0015056///corticotrophin-releasing factor receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0051458///corticotropin secretion+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:2000852///regulation of corticosterone secretion","LINC02210-CRHR1 readthrough","[CRFR1_HUMAN|Reviewed]RecName: Full=Corticotropin-releasing factor receptor 1; Short=CRF-R-1; Short=CRF-R1; Short=CRFR-1; AltName: Full=Corticotropin-releasing hormone receptor 1; Short=CRH-R-1; Short=CRH-R1; Flags: Precursor;+++[A0A024R9X9_HUMAN|Unreviewed]SubName: Full=Corticotropin releasing hormone receptor 1, isoform CRA_b {ECO:0000313|EMBL:EAW93558.1};+++[B4DMR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60308, highly similar to Corticotropin-releasing factor receptor 1 {ECO:0000313|EMBL:BAG59977.1};"]
[10491,"'CRTAP'",10285.03,10619,8960,9954.67666666667,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0050821///protein stabilization+++GO:0007283///spermatogenesis+++GO:0018400///peptidyl-proline hydroxylation to 3-hydroxy-L-proline+++GO:0061077///chaperone-mediated protein folding+++GO:1901874///negative regulation of post-translational protein modification","cartilage associated protein","[CRTAP_HUMAN|Reviewed]RecName: Full=Cartilage-associated protein; Flags: Precursor;+++[B4DPA3_HUMAN|Unreviewed]SubName: Full=Cartilage associated protein, isoform CRA_a {ECO:0000313|EMBL:EAW64448.1}; SubName: Full=cDNA FLJ55123, highly similar to Cartilage-associated protein {ECO:0000313|EMBL:BAG60515.1};+++[C9JP16_HUMAN|Unreviewed]SubName: Full=Cartilage-associated protein {ECO:0000313|Ensembl:ENSP00000409997};"]
[10492,"'SYNCRIP'",1613,1168,1320,1367,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0097452///GAIT complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0070937///CRD-mediated mRNA stability complex+++GO:1990904///ribonucleoprotein complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm","GO:0008143///poly(A) binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0001649///osteoblast differentiation+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0006397///mRNA processing+++GO:0016032///viral process+++GO:0071346///cellular response to interferon-gamma+++GO:0006396///RNA processing+++GO:0000398///mRNA splicing, via spliceosome","synaptotagmin binding cytoplasmic RNA interacting protein","[HNRPQ_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein Q; Short=hnRNP Q; AltName: Full=Glycine- and tyrosine-rich RNA-binding protein; Short=GRY-RBP; AltName: Full=NS1-associated protein 1; AltName: Full=Synaptotagmin-binding, cytoplasmic RNA-interacting protein;+++[B7Z645_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein, isoform CRA_b {ECO:0000313|EMBL:EAW48623.1}; SubName: Full=cDNA FLJ50849, highly similar to Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|EMBL:BAH13131.1};+++[F6UXX1_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|Ensembl:ENSP00000397782}; Flags: Fragment;+++[Q05CK9_HUMAN|Unreviewed]SubName: Full=SYNCRIP protein {ECO:0000313|EMBL:AAH24283.1}; Flags: Fragment;+++[Q59GL1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein variant {ECO:0000313|EMBL:BAD92335.1}; Flags: Fragment;"]
[10493,"'VAT1'",6521,7155,6430,6702,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0035578///azurophil granule lumen+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity","GO:0010637///negative regulation of mitochondrial fusion+++GO:0060337///type I interferon signaling pathway+++GO:0043312///neutrophil degranulation","vesicle amine transport 1","[VAT1_HUMAN|Reviewed]RecName: Full=Synaptic vesicle membrane protein VAT-1 homolog; EC=1.-.-.-;+++[A0A024R1Z6_HUMAN|Unreviewed]SubName: Full=Vesicle amine transport protein 1 homolog (T californica), isoform CRA_a {ECO:0000313|EMBL:EAW60918.1};+++[K7EJM4_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000465239}; Flags: Fragment;+++[K7EM19_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000466322}; Flags: Fragment;+++[K7ENX2_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000467131}; Flags: Fragment;+++[K7ER81_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468146}; Flags: Fragment;+++[K7ERT7_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468401}; Flags: Fragment;+++[K7ESA3_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468621}; Flags: Fragment;"]
[10494,"'STK25'",2209,2158,2157,2174.66666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding","GO:0023014///signal transduction by protein phosphorylation+++GO:0051683///establishment of Golgi localization+++GO:0006979///response to oxidative stress+++GO:0090168///Golgi reassembly+++GO:0036481///intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0006468///protein phosphorylation+++GO:0050772///positive regulation of axonogenesis+++GO:0046777///protein autophosphorylation+++GO:0016310///phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0007163///establishment or maintenance of cell polarity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051645///Golgi localization","serine/threonine kinase 25","[STK25_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 25; EC=2.7.11.1; AltName: Full=Ste20-like kinase; AltName: Full=Sterile 20/oxidant stress-response kinase 1; Short=SOK-1; Short=Ste20/oxidant stress response kinase 1;+++[A0A024R4B2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71266.1}; SubName: Full=Serine/threonine kinase 25 isoform 1 {ECO:0000313|EMBL:ALQ33986.1};+++[A0A0S2Z4Y2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 3 {ECO:0000313|EMBL:ALQ33988.1}; Flags: Fragment;+++[A0A0S2Z503_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 2 {ECO:0000313|EMBL:ALQ33987.1};+++[B3KRS6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34842 fis, clone NT2NE2011033, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG52488.1};+++[B4DMA5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59346, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG59817.1};+++[B4DVS7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52778, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG62789.1};+++[B4E185_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61527, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG64697.1};+++[C9J232_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000399212}; Flags: Fragment;+++[C9J6L2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000417020}; Flags: Fragment;+++[C9J8E8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000406208}; Flags: Fragment;+++[C9JCC0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403607}; Flags: Fragment;+++[C9JDH9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000395104}; Flags: Fragment;+++[C9JFA1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404552}; Flags: Fragment;+++[C9JIH8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403866}; Flags: Fragment;+++[C9JJV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404960}; Flags: Fragment;+++[C9JN58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000414191}; Flags: Fragment;+++[C9K0M6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000401114}; Flags: Fragment;+++[E7EM58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000412617}; Flags: Fragment;+++[H7C279_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404469}; Flags: Fragment;+++[Q96BA2_HUMAN|Unreviewed]SubName: Full=STK25 protein {ECO:0000313|EMBL:AAH15793.1};"]
[10495,"'ENOX2'",190,150,156,165.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0009897///external side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0016491///oxidoreductase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0005515///protein binding","GO:0048511///rhythmic process+++GO:0007624///ultradian rhythm+++GO:0055114///oxidation-reduction process+++GO:0040008///regulation of growth","ecto-NOX disulfide-thiol exchanger 2","[ENOX2_HUMAN|Reviewed]RecName: Full=Ecto-NOX disulfide-thiol exchanger 2; AltName: Full=APK1 antigen; AltName: Full=Cytosolic ovarian carcinoma antigen 1; AltName: Full=Tumor-associated hydroquinone oxidase; Short=tNOX; Includes: RecName: Full=Hydroquinone [NADH] oxidase; EC=1.-.-.-; Includes: RecName: Full=Protein disulfide-thiol oxidoreductase; EC=1.-.-.-;+++[A0A0C4DGT9_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000478608};+++[A4QPE1_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI39782.2}; Flags: Fragment;+++[B1AKF7_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000400304}; Flags: Fragment;+++[Q32ND0_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI08714.1}; Flags: Fragment;"]
[10497,"'UNC13B'",1092,878,985,985,"04721///Synaptic vesicle cycle",{"$nulls":3},"GO:0097470///ribbon synapse+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0045202///synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0030672///synaptic vesicle membrane+++GO:0032009///early phagosome+++GO:0048786///presynaptic active zone+++GO:0031594///neuromuscular junction+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098793///presynapse+++GO:0043195///terminal bouton+++GO:0005794///Golgi apparatus+++GO:0044305///calyx of Held+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0017137///Rab GTPase binding+++GO:0030742///GTP-dependent protein binding+++GO:0005516///calmodulin binding+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0006887///exocytosis+++GO:0010808///positive regulation of synaptic vesicle priming+++GO:1900426///positive regulation of defense response to bacterium+++GO:0007268///chemical synaptic transmission+++GO:0050714///positive regulation of protein secretion+++GO:0035556///intracellular signal transduction+++GO:0016081///synaptic vesicle docking+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0061789///dense core granule priming+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0043065///positive regulation of apoptotic process+++GO:0060384///innervation+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:0007528///neuromuscular junction development+++GO:0035249///synaptic transmission, glutamatergic+++GO:0090382///phagosome maturation+++GO:0071333///cellular response to glucose stimulus+++GO:0016079///synaptic vesicle exocytosis+++GO:0031914///negative regulation of synaptic plasticity","unc-13 homolog B","[UN13B_HUMAN|Reviewed]RecName: Full=Protein unc-13 homolog B; AltName: Full=Munc13-2; Short=munc13;+++[A0A0U1RRB5_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489441}; Flags: Fragment;+++[A0A0U1RRL2_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489581};+++[A0A1B0GUS7_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490228};+++[A0A1B0GVW8_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490683};+++[B1AM27_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000380006};+++[F8W8M9_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000367757};+++[I6L9J0_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000484432}; SubName: Full=UNC13B protein {ECO:0000313|EMBL:AAI11801.1};+++[Q4LE73_HUMAN|Unreviewed]SubName: Full=UNC13B variant protein {ECO:0000313|EMBL:BAE06080.1}; Flags: Fragment;"]
[10498,"'CARM1'",1920,2131,2001,2017.33333333333,"01522///Endocrine resistance",null,null,"R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0042054///histone methyltransferase activity+++GO:0035642///histone methyltransferase activity (H3-R17 specific)+++GO:0042803///protein homodimerization activity+++GO:0070577///lysine-acetylated histone binding+++GO:0008013///beta-catenin binding+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0016274///protein-arginine N-methyltransferase activity","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0016571///histone methylation+++GO:0071168///protein localization to chromatin+++GO:0019216///regulation of lipid metabolic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006479///protein methylation+++GO:0032259///methylation+++GO:0034971///histone H3-R17 methylation+++GO:0060350///endochondral bone morphogenesis+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0016032///viral process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0051591///response to cAMP+++GO:1902415///regulation of mRNA binding+++GO:0034970///histone H3-R2 methylation+++GO:0003420///regulation of growth plate cartilage chondrocyte proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0006325///chromatin organization+++GO:0007568///aging+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:2000171///negative regulation of dendrite development+++GO:0032091///negative regulation of protein binding+++GO:0034969///histone arginine methylation","coactivator associated arginine methyltransferase 1","[CARM1_HUMAN|Reviewed]RecName: Full=Histone-arginine methyltransferase CARM1; EC=2.1.1.319 {ECO:0000269|PubMed:19405910}; AltName: Full=Coactivator-associated arginine methyltransferase 1; AltName: Full=Protein arginine N-methyltransferase 4;+++[K7EIQ8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000464852}; Flags: Fragment;+++[K7EK20_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000465417}; Flags: Fragment;+++[K7EPK1_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467420};+++[K7EQA8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467746}; Flags: Fragment;+++[K7EQB9_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467761}; Flags: Fragment;+++[K7ERM3_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000468319}; Flags: Fragment;"]
[10499,"'NCOA2'",446,266,366,359.333333333333,"04915///Estrogen signaling pathway+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0005102///signaling receptor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0019904///protein domain specific binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0035257///nuclear hormone receptor binding+++GO:0016922///nuclear receptor binding+++GO:0003713///transcription coactivator activity","GO:0048511///rhythmic process+++GO:0032570///response to progesterone+++GO:0015721///bile acid and bile salt transport+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010906///regulation of glucose metabolic process+++GO:0007623///circadian rhythm+++GO:0032870///cellular response to hormone stimulus+++GO:0045475///locomotor rhythm+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0032922///circadian regulation of gene expression+++GO:1904017///cellular response to Thyroglobulin triiodothyronine+++GO:0019216///regulation of lipid metabolic process+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II","nuclear receptor coactivator 2","[NCOA2_HUMAN|Reviewed]RecName: Full=Nuclear receptor coactivator 2; Short=NCoA-2; AltName: Full=Class E basic helix-loop-helix protein 75; Short=bHLHe75; AltName: Full=Transcriptional intermediary factor 2; Short=hTIF2;+++[A0A0B6XJZ8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|EMBL:CEF49517.1}; Flags: Fragment;+++[A0A1D5RMT0_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430850}; Flags: Fragment;+++[B4DPW8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51272, highly similar to Nuclear receptor coactivator 2 {ECO:0000313|EMBL:BAG60730.1};+++[E5RFN9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430348}; Flags: Fragment;+++[E7EWM1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430148};+++[H0YBB6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000429132}; Flags: Fragment;+++[Q569J4_HUMAN|Unreviewed]SubName: Full=NCOA2 protein {ECO:0000313|EMBL:AAH92442.1};"]
[1050,"'CEBPA'",16,17,16,16.3333333333333,"05221///Acute myeloid leukemia+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05202///Transcriptional misregulation in cancer+++05200///Pathways in cancer","H00003///Acute myeloid leukemia (AML)",null,null,"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001013///RNA polymerase I regulatory region DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0001892///embryonic placenta development+++GO:0008285///negative regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0030225///macrophage differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006351///transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0030851///granulocyte differentiation+++GO:0050873///brown fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071285///cellular response to lithium ion+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0043032///positive regulation of macrophage activation+++GO:0055088///lipid homeostasis+++GO:0030324///lung development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0045444///fat cell differentiation+++GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000050///urea cycle+++GO:0030099///myeloid cell differentiation+++GO:0008203///cholesterol metabolic process+++GO:0007005///mitochondrion organization+++GO:0048839///inner ear development+++GO:0050872///white fat cell differentiation+++GO:0071407///cellular response to organic cyclic compound+++GO:0048469///cell maturation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006091///generation of precursor metabolites and energy+++GO:0007219///Notch signaling pathway+++GO:0042593///glucose homeostasis+++GO:0006360///transcription by RNA polymerase I","CCAAT enhancer binding protein alpha","[CEBPA_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein alpha {ECO:0000312|HGNC:HGNC:1833}; Short=C/EBP alpha {ECO:0000312|HGNC:HGNC:1833};"]
[10500,"'SEMA6C'",117,95,104,105.333333333333,"04360///Axon guidance",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface","GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0001755///neural crest cell migration+++GO:0030335///positive regulation of cell migration+++GO:0050919///negative chemotaxis+++GO:0007399///nervous system development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0030517///negative regulation of axon extension+++GO:0030154///cell differentiation+++GO:0048843///negative regulation of axon extension involved in axon guidance","semaphorin 6C","[SEM6C_HUMAN|Reviewed]RecName: Full=Semaphorin-6C; AltName: Full=Semaphorin-Y; Short=Sema Y; Flags: Precursor;+++[A0A087WYX3_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000482163};+++[A0A087X0A5_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000483227};+++[Q1RMY5_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14624.1};+++[Q24JR3_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14522.1};"]
[10501,"'SEMA6B'",828,917,715,820,"04360///Axon guidance",{"$nulls":3},"GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0030335///positive regulation of cell migration+++GO:0030154///cell differentiation+++GO:0007399///nervous system development","semaphorin 6B","[SEM6B_HUMAN|Reviewed]RecName: Full=Semaphorin-6B; AltName: Full=Semaphorin-Z; Short=Sema Z; Flags: Precursor;+++[Q9BXR8_HUMAN|Unreviewed]SubName: Full=Semaphorin 6B isoform 2 {ECO:0000313|EMBL:AAK16831.1};"]
[10505,"'SEMA4F'",386.09,325.2,342.68,351.323333333333,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0031290///retinal ganglion cell axon guidance+++GO:0030154///cell differentiation+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0001755///neural crest cell migration+++GO:0007411///axon guidance+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis","ssemaphorin 4F","[SEM4F_HUMAN|Reviewed]RecName: Full=Semaphorin-4F; AltName: Full=Semaphorin-M; Short=Sema M; AltName: Full=Semaphorin-W; Short=Sema W; Flags: Precursor;+++[A0A087WYZ7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000482238};+++[B7Z931_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52836, highly similar to Semaphorin-4F {ECO:0000313|EMBL:BAH14167.1};+++[C9JKW7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000409141}; Flags: Fragment;+++[C9K0A1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000407698}; Flags: Fragment;+++[F8WCP8_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000416490};+++[F8WD61_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000396703};+++[F8WEH3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000413882};"]
[10507,"'SEMA4D'",273.4,237.07,243.5,251.323333333333,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0004888///transmembrane signaling receptor activity","GO:0008360///regulation of cell shape+++GO:0030335///positive regulation of cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0050919///negative chemotaxis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0050772///positive regulation of axonogenesis+++GO:0007275///multicellular organism development+++GO:0006955///immune response+++GO:0048814///regulation of dendrite morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:1900220///semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis+++GO:0048672///positive regulation of collateral sprouting+++GO:0070486///leukocyte aggregation+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0043931///ossification involved in bone maturation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0007155///cell adhesion+++GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0030154///cell differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007399///nervous system development+++GO:0043547///positive regulation of GTPase activity+++GO:0031344///regulation of cell projection organization+++GO:0045668///negative regulation of osteoblast differentiation","semaphorin 4D","[SEM4D_HUMAN|Reviewed]RecName: Full=Semaphorin-4D; AltName: Full=A8; AltName: Full=BB18; AltName: Full=GR3; AltName: CD_antigen=CD100; Flags: Precursor;+++[A0A0C4DG45_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000399948};+++[C9JD54_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000416747}; Flags: Fragment;+++[C9JFP1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000390754}; Flags: Fragment;+++[C9JYS7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000413352}; Flags: Fragment;+++[E9PFD9_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000395222};+++[F5H044_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000438389}; Flags: Fragment;+++[Q4LE41_HUMAN|Unreviewed]SubName: Full=SEMA4D variant protein {ECO:0000313|EMBL:BAE06112.1}; Flags: Fragment;"]
[10509,"'SEMA4B'",435,480,474,463,"04360///Axon guidance","H00527///Retinitis pigmentosa (RP)+++H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0030335///positive regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis+++GO:0030154///cell differentiation+++GO:0071526///semaphorin-plexin signaling pathway","semaphorin 4B","[SEM4B_HUMAN|Reviewed]RecName: Full=Semaphorin-4B; Flags: Precursor;+++[H0YKV7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000452957};+++[H0YLN3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453272}; Flags: Fragment;+++[H0YM68_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453484};+++[H0YMD6_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453563}; Flags: Fragment;+++[H0YMR1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453705}; Flags: Fragment;+++[H0YMZ3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453804}; Flags: Fragment;+++[H0YN49_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453866}; Flags: Fragment;+++[H0YNC4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453951}; Flags: Fragment;+++[H0YNM2_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000454068}; Flags: Fragment;+++[J3KNP4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000332204};+++[Q4VBY2_HUMAN|Unreviewed]SubName: Full=SEMA4B protein {ECO:0000313|EMBL:AAH94849.1}; Flags: Fragment;"]
[1051,"'CEBPB'",1360,1644,1544,1516,"05152///Tuberculosis+++04668///TNF signaling pathway+++05202///Transcriptional misregulation in cancer+++04657///IL-17 signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0036488///CHOP-C/EBP complex+++GO:0000779///condensed chromosome, centromeric region+++GO:0000790///nuclear chromatin+++GO:0016363///nuclear matrix+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0035259///glucocorticoid receptor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0042826///histone deacetylase binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0045444///fat cell differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901329///regulation of odontoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0042742///defense response to bacterium+++GO:0045408///regulation of interleukin-6 biosynthetic process+++GO:0035711///T-helper 1 cell activation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0070169///positive regulation of biomineral tissue development+++GO:0032753///positive regulation of interleukin-4 production+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001541///ovarian follicle development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0071347///cellular response to interleukin-1+++GO:0001889///liver development+++GO:0042130///negative regulation of T cell proliferation+++GO:0034976///response to endoplasmic reticulum stress+++GO:2000120///positive regulation of sodium-dependent phosphate transport+++GO:0007613///memory+++GO:0071407///cellular response to organic cyclic compound+++GO:0071230///cellular response to amino acid stimulus+++GO:0001892///embryonic placenta development+++GO:0006366///transcription by RNA polymerase II+++GO:0002432///granuloma formation+++GO:0050873///brown fat cell differentiation+++GO:0097421///liver regeneration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:0045600///positive regulation of fat cell differentiation+++GO:0030182///neuron differentiation+++GO:0072574///hepatocyte proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045670///regulation of osteoclast differentiation+++GO:0030154///cell differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0060850///regulation of transcription involved in cell fate commitment+++GO:2001198///regulation of dendritic cell differentiation","CCAAT enhancer binding protein beta","[CEBPB_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein beta {ECO:0000312|HGNC:HGNC:1834}; Short=C/EBP beta {ECO:0000312|HGNC:HGNC:1834}; AltName: Full=Liver activator protein; Short=LAP; AltName: Full=Liver-enriched inhibitory protein; Short=LIP; AltName: Full=Nuclear factor NF-IL6 {ECO:0000303|PubMed:1741402}; AltName: Full=Transcription factor 5; Short=TCF-5;+++[Q9BSC0_HUMAN|Unreviewed]SubName: Full=CEBPB protein {ECO:0000313|EMBL:AAH05132.2}; Flags: Fragment;+++[W8SNU6_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26745.1}; Flags: Fragment;+++[W8SNV5_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26755.1}; Flags: Fragment;"]
[10512,"'SEMA3C'",4788,2765,3545,3699.33333333333,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0050919///negative chemotaxis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0003350///pulmonary myocardium development+++GO:0006955///immune response+++GO:0060174///limb bud formation+++GO:0140074///cardiac endothelial to mesenchymal transition+++GO:0001755///neural crest cell migration+++GO:0007507///heart development+++GO:0042493///response to drug+++GO:0030154///cell differentiation+++GO:0009791///post-embryonic development+++GO:0001756///somitogenesis+++GO:0007275///multicellular organism development+++GO:0021915///neural tube development+++GO:0003148///outflow tract septum morphogenesis+++GO:0007399///nervous system development+++GO:0001974///blood vessel remodeling+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0003151///outflow tract morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0007411///axon guidance+++GO:1905312///positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching","semaphorin 3C","[SEM3C_HUMAN|Reviewed]RecName: Full=Semaphorin-3C; AltName: Full=Semaphorin-E; Short=Sema E; Flags: Precursor;+++[F2Z2Y0_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000395398};+++[F8WEP9_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000393825};+++[Q75L25_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS07489.1}; Flags: Fragment;+++[Q75MX0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS00351.1}; Flags: Fragment;"]
[10513,"'APPBP2'",538,386.97,469,464.656666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005875///microtubule associated complex+++GO:0005874///microtubule+++GO:0005634///nucleus","GO:0003777///microtubule motor activity+++GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0046907///intracellular transport","amyloid beta precursor protein binding protein 2","[APBP2_HUMAN|Reviewed]RecName: Full=Amyloid protein-binding protein 2; AltName: Full=Amyloid beta precursor protein-binding protein 2; Short=APP-BP2; AltName: Full=Protein interacting with APP tail 1;+++[A0A024QZ47_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW51407.1};+++[K7EIZ9_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000464962}; Flags: Fragment;+++[K7EN61_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000466802};+++[K7ENN3_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000467025};"]
[10514,"'MYBBP1A'",1502,1381,1313,1398.66666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0042564///NLS-dependent protein nuclear import complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0043565///sequence-specific DNA binding+++GO:0070888///E-box binding+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:2000210///positive regulation of anoikis+++GO:0042254///ribosome biogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0001649///osteoblast differentiation+++GO:0071158///positive regulation of cell cycle arrest+++GO:0032922///circadian regulation of gene expression+++GO:0022904///respiratory electron transport chain+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0048511///rhythmic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042149///cellular response to glucose starvation+++GO:0045815///positive regulation of gene expression, epigenetic","MYB binding protein 1a","[MBB1A_HUMAN|Reviewed]RecName: Full=Myb-binding protein 1A;+++[I3L1L3_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000458919}; Flags: Fragment;+++[I3L2H8_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000459692}; Flags: Fragment;+++[I3L311_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000460087}; Flags: Fragment;"]
[10516,"'FBLN5'",8299,8287,9111,8565.66666666667,null,"H00821///Age-related macular degeneration+++H00557///Cutis laxa",null,null,"GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:0031012///extracellular matrix+++GO:0071953///elastic fiber+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0008022///protein C-terminus binding+++GO:0042803///protein homodimerization activity+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0005509///calcium ion binding","GO:2000121///regulation of removal of superoxide radicals+++GO:0048251///elastic fiber assembly+++GO:0030198///extracellular matrix organization+++GO:0034394///protein localization to cell surface+++GO:0007160///cell-matrix adhesion+++GO:0007155///cell adhesion+++GO:0001558///regulation of cell growth+++GO:0046903///secretion","fibulin 5","[FBLN5_HUMAN|Reviewed]RecName: Full=Fibulin-5; Short=FIBL-5; AltName: Full=Developmental arteries and neural crest EGF-like protein; Short=Dance; AltName: Full=Urine p50 protein; Short=UP50; Flags: Precursor;+++[A0A024R6G3_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_b {ECO:0000313|EMBL:EAW81467.1}; SubName: Full=Testis tissue sperm-binding protein Li 75n {ECO:0000313|EMBL:AEE61295.1};+++[G3V2P8_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000450787};+++[G3V329_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451002};+++[G3V3Y2_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451486}; Flags: Fragment;+++[G3V4U0_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451982};+++[G3XA98_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_a {ECO:0000313|EMBL:EAW81465.1}; SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000267620};"]
[10517,"'FBXW10'",1,1,2.45,1.48333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0000209///protein polyubiquitination","F-box and WD repeat domain containing 10","[FBW10_HUMAN|Reviewed]RecName: Full=F-box/WD repeat-containing protein 10; AltName: Full=F-box and WD-40 domain-containing protein 10; AltName: Full=Ubiquitin ligase-specificity factor;+++[J3QLH9_HUMAN|Unreviewed]SubName: Full=F-box/WD repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000463552};"]
[10518,"'CIB2'",100,112,96,102.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0042383///sarcolemma+++GO:0005737///cytoplasm+++GO:0032437///cuticular plate+++GO:0005929///cilium+++GO:0005886///plasma membrane+++GO:0005927///muscle tendon junction+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0001750///photoreceptor outer segment+++GO:0016020///membrane+++GO:0072562///blood microparticle+++GO:0032420///stereocilium+++GO:0001917///photoreceptor inner segment","GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0071318///cellular response to ATP+++GO:0055074///calcium ion homeostasis+++GO:0045494///photoreceptor cell maintenance+++GO:0007204///positive regulation of cytosolic calcium ion concentration","calcium and integrin binding family member 2","[CIB2_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding family member 2; AltName: Full=Kinase-interacting protein 2; Short=KIP 2;+++[A0A2R8Y4Y2_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000494155}; Flags: Fragment;+++[H0YKC8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452752};+++[H0YKX8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452980}; Flags: Fragment;+++[H0YLL7_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453256}; Flags: Fragment;+++[H0YLX3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453377}; Flags: Fragment;+++[H0YML3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453654}; Flags: Fragment;+++[H0YND4_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453963};"]
[10519,"'CIB1'",945,1109,1019,1024.33333333333,"04137///Mitophagy - animal+++04360///Axon guidance+++04140///Autophagy - animal","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016324///apical plasma membrane+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0032433///filopodium tip+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0031982///vesicle+++GO:0030424///axon+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030426///growth cone+++GO:0005815///microtubule organizing center+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0032587///ruffle membrane+++GO:0043025///neuronal cell body+++GO:0071944///cell periphery","GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017016///Ras GTPase binding+++GO:0005509///calcium ion binding+++GO:0044325///ion channel binding+++GO:0043495///protein membrane anchor+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding","GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0071363///cellular response to growth factor stimulus+++GO:0010977///negative regulation of neuron projection development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0007155///cell adhesion+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0042127///regulation of cell proliferation+++GO:0001525///angiogenesis+++GO:0007286///spermatid development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:2000256///positive regulation of male germ cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0001934///positive regulation of protein phosphorylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0051301///cell division+++GO:0030307///positive regulation of cell growth+++GO:0030220///platelet formation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0002931///response to ischemia+++GO:0031122///cytoplasmic microtubule organization+++GO:0008285///negative regulation of cell proliferation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007113///endomitotic cell cycle+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0006302///double-strand break repair+++GO:0007049///cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043085///positive regulation of catalytic activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0051302///regulation of cell division+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0008284///positive regulation of cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006915///apoptotic process+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007283///spermatogenesis","calcium and integrin binding 1","[CIB1_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding protein 1; Short=CIB; AltName: Full=Calcium- and integrin-binding protein; Short=CIBP; AltName: Full=Calmyrin; AltName: Full=DNA-PKcs-interacting protein; AltName: Full=Kinase-interacting protein; Short=KIP; AltName: Full=SNK-interacting protein 2-28; Short=SIP2-28;+++[A0A140VK09_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 9 {ECO:0000313|EMBL:AEE61146.1};"]
[1052,"'CEBPD'",350,290,412,350.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II","CCAAT enhancer binding protein delta","[CEBPD_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein delta; Short=C/EBP delta; AltName: Full=Nuclear factor NF-IL6-beta {ECO:0000303|PubMed:1741402}; Short=NF-IL6-beta {ECO:0000303|PubMed:1741402};+++[Q504X4_HUMAN|Unreviewed]SubName: Full=CEBPD protein {ECO:0000313|EMBL:AAH94715.1};"]
[10520,"'ZNF211'",103,106,138,115.666666666667,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 211","[ZN211_HUMAN|Reviewed]RecName: Full=Zinc finger protein 211; AltName: Full=Zinc finger protein C2H2-25;+++[A0A0A0MTK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442601};+++[F5GY70_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000440793};+++[F5H771_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442740};+++[H0Y3T8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000384436}; Flags: Fragment;"]
[10521,"'DDX17'",3266,2426,2996,2896,{"$nulls":4},"GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005730///nucleolus","GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008186///RNA-dependent ATPase activity+++GO:0003724///RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding","GO:0045445///myoblast differentiation+++GO:0006396///RNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0010586///miRNA metabolic process+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031047///gene silencing by RNA+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0002376///immune system process+++GO:0030521///androgen receptor signaling pathway+++GO:0001837///epithelial to mesenchymal transition+++GO:0051607///defense response to virus+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006364///rRNA processing+++GO:0006357///regulation of transcription by RNA polymerase II","DEAD-box helicase 17","[DDX17_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX17; EC=3.6.4.13; AltName: Full=DEAD box protein 17; AltName: Full=DEAD box protein p72; AltName: Full=DEAD box protein p82 {ECO:0000303|PubMed:19995069}; AltName: Full=RNA-dependent helicase p72;+++[A0A0U1RQJ0_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000489029}; Flags: Fragment;+++[A0A1W2PQ51_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000491776};+++[A0A1X7SBZ2_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000385536};+++[Q59F66_HUMAN|Unreviewed]SubName: Full=DEAD box polypeptide 17 isoform p82 variant {ECO:0000313|EMBL:BAD92832.1}; Flags: Fragment;"]
[10522,"'DEAF1'",1300,1571,1303,1391.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center+++GO:0005667///transcription factor complex+++GO:0005902///microvillus+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0016605///PML body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0001931///uropod","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding+++GO:0030544///Hsp70 protein binding","GO:0007275///multicellular organism development+++GO:0050900///leukocyte migration+++GO:0009653///anatomical structure morphogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0006935///chemotaxis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050863///regulation of T cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0050901///leukocyte tethering or rolling+++GO:0006955///immune response+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007281///germ cell development+++GO:0001843///neural tube closure+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0006366///transcription by RNA polymerase II+++GO:2000406///positive regulation of T cell migration+++GO:0006968///cellular defense response+++GO:0008542///visual learning+++GO:0042742///defense response to bacterium+++GO:0048706///embryonic skeletal system development+++GO:0007163///establishment or maintenance of cell polarity+++GO:2000404///regulation of T cell migration+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0032609///interferon-gamma production+++GO:0042535///positive regulation of tumor necrosis factor biosynthetic process+++GO:0001662///behavioral fear response","DEAF1 transcription factor","[DEAF1_HUMAN|Reviewed]RecName: Full=Deformed epidermal autoregulatory factor 1 homolog; AltName: Full=Nuclear DEAF-1-related transcriptional regulator; Short=NUDR; AltName: Full=Suppressin; AltName: Full=Zinc finger MYND domain-containing protein 5;+++[A0A0J9YWD6_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000487909}; Flags: Fragment;+++[A0A0J9YX80_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488285}; Flags: Fragment;+++[A0A0J9YXA4_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488313}; Flags: Fragment;+++[C9JUK7_HUMAN|Unreviewed]SubName: Full=Leukosialin {ECO:0000313|Ensembl:ENSP00000412907}; Flags: Fragment;+++[H0YCH1_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000431563}; Flags: Fragment;+++[H0YCY2_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000432518}; Flags: Fragment;"]
[10523,"'CHERP'",1746,1513,1699,1652.66666666667,"03040///Spliceosome",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005623///cell+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0044325///ion channel binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0006874///cellular calcium ion homeostasis+++GO:0007399///nervous system development+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0008285///negative regulation of cell proliferation+++GO:0051209///release of sequestered calcium ion into cytosol","calcium homeostasis endoplasmic reticulum protein","[CHERP_HUMAN|Reviewed]RecName: Full=Calcium homeostasis endoplasmic reticulum protein; AltName: Full=ERPROT 213-21; AltName: Full=SR-related CTD-associated factor 6;+++[J3QK89_HUMAN|Unreviewed]SubName: Full=Calcium homeostasis endoplasmic reticulum protein {ECO:0000313|Ensembl:ENSP00000198939};"]
[10524,"'KAT5'",494.99,602.96,623,573.65,"05166///HTLV-I infection","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0000123///histone acetyltransferase complex+++GO:0005730///nucleolus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000790///nuclear chromatin+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0000812///Swr1 complex","GO:0070491///repressing transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0016740///transferase activity+++GO:0042393///histone binding+++GO:0005515///protein binding+++GO:0010485///H4 histone acetyltransferase activity+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0016407///acetyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004402///histone acetyltransferase activity","GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1901985///positive regulation of protein acetylation+++GO:0016032///viral process+++GO:0006302///double-strand break repair+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0000729///DNA double-strand break processing+++GO:0016573///histone acetylation+++GO:0040008///regulation of growth+++GO:0032703///negative regulation of interleukin-2 production+++GO:0010212///response to ionizing radiation+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0071392///cellular response to estradiol stimulus+++GO:0006260///DNA replication+++GO:0030521///androgen receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","lysine acetyltransferase 5","[KAT5_HUMAN|Reviewed]RecName: Full=Histone acetyltransferase KAT5; EC=2.3.1.48 {ECO:0000269|PubMed:10096020, ECO:0000269|PubMed:12468530, ECO:0000269|PubMed:29040603}; AltName: Full=60 kDa Tat-interactive protein; Short=Tip60 {ECO:0000303|PubMed:10096020, ECO:0000303|PubMed:11416127, ECO:0000303|PubMed:12801643, ECO:0000303|PubMed:29040603}; AltName: Full=Histone acetyltransferase HTATIP; Short=HIV-1 Tat interactive protein; AltName: Full=Lysine acetyltransferase 5; AltName: Full=cPLA(2)-interacting protein;+++[A0A024R597_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[A0A024R5E8_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PJI1_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PMG8_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000434993}; Flags: Fragment;+++[E9PRL6_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436012}; Flags: Fragment;+++[E9PRM3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436000}; Flags: Fragment;+++[E9PRS1_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435939}; Flags: Fragment;+++[H0YEG3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435766}; Flags: Fragment;+++[H0YEP0_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436247}; Flags: Fragment;"]
[10525,"'HYOU1'",7975,7789,7427,7730.33333333333,"04141///Protein processing in endoplasmic reticulum","H00118///Congenital disorders of glycosylation (CDG) type I+++H00770///Congenital myasthenic syndrome","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0016020///membrane+++GO:0071682///endocytic vesicle lumen+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005925///focal adhesion","GO:0051087///chaperone binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0036498///IRE1-mediated unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006898///receptor-mediated endocytosis+++GO:0043066///negative regulation of apoptotic process+++GO:1903382///negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway+++GO:0071456///cellular response to hypoxia+++GO:0002931///response to ischemia+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway","hypoxia up-regulated 1","[HYOU1_HUMAN|Reviewed]RecName: Full=Hypoxia up-regulated protein 1; AltName: Full=150 kDa oxygen-regulated protein; Short=ORP-150; AltName: Full=170 kDa glucose-regulated protein; Short=GRP-170; Flags: Precursor;+++[A0A024R3G0_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated 1, isoform CRA_a {ECO:0000313|EMBL:EAW67441.1};+++[A0A087WW13_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000479845}; Flags: Fragment;+++[A0A087WWI4_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000480248};+++[A0A087X054_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000483106};+++[A0A087X214_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000484622}; Flags: Fragment;+++[B3KXH0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45395 fis, clone BRHIP3027191, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAG54482.1};+++[B7Z602_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59408, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13088.1};+++[B7Z766_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54564, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13502.1};+++[E9PJ21_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000431874}; Flags: Fragment;+++[J3KSR2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000464026};+++[J3KTF1_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000462951}; Flags: Fragment;+++[J3QL06_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463318}; Flags: Fragment;+++[J3QLE9_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463515}; Flags: Fragment;+++[J3QQH7_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463742}; Flags: Fragment;+++[K7EQK2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000467866};+++[Q05D91_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH17726.1}; Flags: Fragment;+++[Q6IN67_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH72436.1};+++[Q9BST8_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH04560.1}; SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000482199};"]
[10526,"'IPO8'",489,379,407,425,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005623///cell+++GO:0005635///nuclear envelope","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0060964///regulation of gene silencing by miRNA+++GO:0006886///intracellular protein transport+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction","importin 8","[IPO8_HUMAN|Reviewed]RecName: Full=Importin-8; Short=Imp8; AltName: Full=Ran-binding protein 8; Short=RanBP8;+++[A0A087WXH2_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000481026}; Flags: Fragment;+++[F5GXT5_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000440979}; Flags: Fragment;+++[F5H009_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000444050}; Flags: Fragment;+++[F5H244_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439556}; Flags: Fragment;+++[F5H292_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439413}; Flags: Fragment;+++[F5H2I3_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446254}; Flags: Fragment;+++[F5H815_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000443789};+++[H0YH64_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446232}; Flags: Fragment;"]
[10527,"'IPO7'",1467,1096,1203,1255.33333333333,"04013///MAPK signaling pathway - fly",{"$nulls":3},"GO:0016020///membrane+++GO:0005623///cell+++GO:0005654///nucleoplasm+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005643///nuclear pore","GO:0008536///Ran GTPase binding+++GO:0008565///protein transporter activity+++GO:0042393///histone binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0030695///GTPase regulator activity","GO:0045087///innate immune response+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process","importin 7","[IPO7_HUMAN|Reviewed]RecName: Full=Importin-7; Short=Imp7; AltName: Full=Ran-binding protein 7; Short=RanBP7;+++[B3KNG9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14581 fis, clone NT2RM4001382, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51331.1}; SubName: Full=cDNA FLJ14986 fis, clone Y79AA1000784, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51391.1};+++[E9PLB2_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000435235}; Flags: Fragment;+++[E9PLJ0_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000433313};+++[L8E8A9_HUMAN|Unreviewed]SubName: Full=Alternative protein IPO7 {ECO:0000313|EMBL:CCQ43354.1};"]
[10528,"'NOP56'",880,868,913,887,"03008///Ribosome biogenesis in eukaryotes","H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0031428///box C/D snoRNP complex+++GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:1990226///histone methyltransferase binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis","NOP56 ribonucleoprotein","[NOP56_HUMAN|Reviewed]RecName: Full=Nucleolar protein 56; AltName: Full=Nucleolar protein 5A;+++[A0PJ92_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH18421.1}; Flags: Fragment;+++[H0Y653_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000403199}; Flags: Fragment;+++[H0YDU4_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000434317}; Flags: Fragment;+++[Q5JXT2_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000388497}; Flags: Fragment;+++[Q9BSN3_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH04937.1};"]
[10529,"'NEBL'",54,33,57,48,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0031005///filamin binding+++GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding+++GO:0008307///structural constituent of muscle+++GO:0005523///tropomyosin binding","GO:0071691///cardiac muscle thin filament assembly","nebulette","[NEBL_HUMAN|Reviewed]RecName: Full=Nebulette; AltName: Full=Actin-binding Z-disk protein;+++[A0A0U1RQY0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489224}; Flags: Fragment;+++[A0A0U1RRI4_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489545}; Flags: Fragment;+++[A0A0U1RRK0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489562}; Flags: Fragment;+++[B0YJ47_HUMAN|Unreviewed]SubName: Full=Nebulette variant 4 {ECO:0000313|EMBL:ACA06025.1};+++[Q2TBD1_HUMAN|Unreviewed]SubName: Full=NEBL protein {ECO:0000313|EMBL:AAI10453.1};+++[Q59FZ8_HUMAN|Unreviewed]SubName: Full=Nebulette non-muscle isoform variant {ECO:0000313|EMBL:BAD92548.1}; Flags: Fragment;+++[Q5JUU7_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000396512}; Flags: Fragment;+++[Q5JUU8_HUMAN|Unreviewed]SubName: Full=Nebulette variant 6 {ECO:0000313|EMBL:ACA06021.1};"]
[10531,"'PITRM1'",1947,1811,1911,1889.66666666667,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008047///enzyme activator activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity","GO:0043085///positive regulation of catalytic activity+++GO:0006508///proteolysis+++GO:0006626///protein targeting to mitochondrion","pitrilysin metallopeptidase 1","[PREP_HUMAN|Reviewed]RecName: Full=Presequence protease, mitochondrial {ECO:0000305|PubMed:16849325}; Short=hPreP {ECO:0000303|PubMed:16849325}; EC=3.4.24.- {ECO:0000269|PubMed:10360838, ECO:0000269|PubMed:16849325, ECO:0000269|PubMed:19196155, ECO:0000269|PubMed:24931469}; AltName: Full=Pitrilysin metalloproteinase 1 {ECO:0000303|PubMed:10360838}; Short=Metalloprotease 1 {ECO:0000303|PubMed:10360838}; Short=hMP1 {ECO:0000303|PubMed:10360838}; Flags: Precursor;+++[A0A0A0MRX9_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000370382};+++[B1APQ0_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000399307}; Flags: Fragment;+++[B1APQ1_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000402072}; Flags: Fragment;+++[H0Y4F7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000391526}; Flags: Fragment;+++[H0Y7L7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000413687}; Flags: Fragment;"]
[10533,"'ATG7'",227,235,273,245,"04136///Autophagy - other+++04140///Autophagy - animal+++04138///Autophagy - yeast+++04216///Ferroptosis",{"$nulls":3},"GO:0005930///axoneme+++GO:0034774///secretory granule lumen+++GO:0000407///phagophore assembly site+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0030424///axon+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity+++GO:0019778///Atg12 activating enzyme activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019779///Atg8 activating enzyme activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0004839///ubiquitin activating enzyme activity","GO:0071315///cellular response to morphine+++GO:0006464///cellular protein modification process+++GO:0042752///regulation of circadian rhythm+++GO:0061025///membrane fusion+++GO:0006501///C-terminal protein lipidation+++GO:0016567///protein ubiquitination+++GO:0039521///suppression by virus of host autophagy+++GO:0000422///autophagy of mitochondrion+++GO:0051607///defense response to virus+++GO:0007568///aging+++GO:0031401///positive regulation of protein modification process+++GO:0045732///positive regulation of protein catabolic process+++GO:0060548///negative regulation of cell death+++GO:0043312///neutrophil degranulation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:1902617///response to fluoride+++GO:0090298///negative regulation of mitochondrial DNA replication+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0006995///cellular response to nitrogen starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0010508///positive regulation of autophagy+++GO:0031667///response to nutrient levels+++GO:1901214///regulation of neuron death+++GO:0016236///macroautophagy+++GO:0009749///response to glucose+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0044805///late nucleophagy+++GO:0071455///cellular response to hyperoxia+++GO:0000045///autophagosome assembly+++GO:0009267///cellular response to starvation+++GO:0061684///chaperone-mediated autophagy","autophagy related 7","[ATG7_HUMAN|Reviewed]RecName: Full=Ubiquitin-like modifier-activating enzyme ATG7; AltName: Full=ATG12-activating enzyme E1 ATG7; AltName: Full=Autophagy-related protein 7; Short=APG7-like; Short=hAGP7; AltName: Full=Ubiquitin-activating enzyme E1-like protein;+++[A0A024R2E9_HUMAN|Unreviewed]SubName: Full=ATG7 autophagy related 7 homolog (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW64097.1};+++[B3KQM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90740 fis, clone PLACE1011045, highly similar to Autophagy-related protein 7 {ECO:0000313|EMBL:BAG52088.1};+++[C9J415_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000411880}; Flags: Fragment;+++[C9JE55_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000416644}; Flags: Fragment;+++[C9JFF4_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000415223}; Flags: Fragment;+++[C9JGL2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000390547}; Flags: Fragment;+++[C9JKA3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389996}; Flags: Fragment;+++[C9JNU2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000408303}; Flags: Fragment;+++[F8WDY9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389012};+++[H7BZ92_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000388295}; Flags: Fragment;+++[H7C059_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000393075}; Flags: Fragment;+++[H7C2J8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000406398}; Flags: Fragment;+++[H7C2R3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000407340}; Flags: Fragment;+++[H7C369_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000409844}; Flags: Fragment;"]
[10534,"'SSSCA1'",344,425,331,366.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0030027///lamellipodium","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","Sjogren syndrome/scleroderma autoantigen 1","[SSA27_HUMAN|Reviewed]RecName: Full=Sjoegren syndrome/scleroderma autoantigen 1; AltName: Full=Autoantigen p27;+++[E9PK41_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000431666};+++[E9PN57_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000432938};+++[G3V1B8_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000434381}; SubName: Full=Sjogren's syndrome/scleroderma autoantigen 1, isoform CRA_b {ECO:0000313|EMBL:EAW74407.1};+++[H0YEB6_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435432}; Flags: Fragment;+++[H0YEK1_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435982}; Flags: Fragment;"]
[10535,"'RNASEH2A'",78,92,88,86,"03030///DNA replication","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0032299///ribonuclease H2 complex+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin+++GO:0005667///transcription factor complex+++GO:0035976///transcription factor AP-1 complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0004518///nuclease activity+++GO:0004540///ribonuclease activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004519///endonuclease activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042493///response to drug+++GO:0001649///osteoblast differentiation+++GO:0034097///response to cytokine+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006401///RNA catabolic process+++GO:0001570///vasculogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0009987///cellular process+++GO:0010033///response to organic substance+++GO:0016070///RNA metabolic process+++GO:0001701///in utero embryonic development+++GO:0051591///response to cAMP+++GO:0009314///response to radiation+++GO:0043137///DNA replication, removal of RNA primer+++GO:0060136///embryonic process involved in female pregnancy+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032496///response to lipopolysaccharide+++GO:0046697///decidualization+++GO:0060716///labyrinthine layer blood vessel development+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0009612///response to mechanical stimulus+++GO:0006260///DNA replication+++GO:0071277///cellular response to calcium ion+++GO:0006298///mismatch repair+++GO:0001829///trophectodermal cell differentiation+++GO:0033687///osteoblast proliferation+++GO:0045597///positive regulation of cell differentiation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0051726///regulation of cell cycle+++GO:0032870///cellular response to hormone stimulus","ribonuclease H2 subunit A","[RNH2A_HUMAN|Reviewed]RecName: Full=Ribonuclease H2 subunit A; Short=RNase H2 subunit A; EC=3.1.26.4; AltName: Full=Aicardi-Goutieres syndrome 4 protein; Short=AGS4; AltName: Full=RNase H(35); AltName: Full=Ribonuclease HI large subunit; Short=RNase HI large subunit; AltName: Full=Ribonuclease HI subunit A;+++[A0A2R8Y606_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[A0A2R8Y658_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515}; Flags: Fragment;+++[Q6IBG3_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[Q6UQL6_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};"]
[10536,"'P3H3'",3703,4000,3502,3735,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:1902494///catalytic complex","GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0051213///dioxygenase activity+++GO:0019797///procollagen-proline 3-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0031418///L-ascorbic acid binding","GO:0032964///collagen biosynthetic process+++GO:0032963///collagen metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0055114///oxidation-reduction process","prolyl 3-hydroxylase 3","[P3H3_HUMAN|Reviewed]RecName: Full=Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318}; EC=1.14.11.7; AltName: Full=Leprecan-like protein 2 {ECO:0000303|PubMed:15063763}; AltName: Full=Protein B {ECO:0000303|PubMed:8723724}; Flags: Precursor;"]
[105369140,"'LOC105369140'",1,1.73,3,1.91,"00380///Tryptophan metabolism+++01100///Metabolic pathways",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin",null,"GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","neuroblastoma breakpoint family member 6-like protein","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369155,"'105369155'",2,3,2,2.33333333333333,{"$nulls":8},"[FBXL2_BOVIN|diamond]RecName: Full=F-box/LRR-repeat protein 2 {ECO:0000305}; AltName: Full=F-box and leucine-rich repeat protein 2 {ECO:0000305};"]
[105369199,"'LOC105369199'",5,3.27,5,4.42333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0030016///myofibril+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0034622///cellular protein-containing complex assembly+++GO:1903358///regulation of Golgi organization+++GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization","neuroblastoma breakpoint family member 6-like protein","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;"]
[105369201,"'LOC105369201'",21,23,34,26,{"$nulls":4},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0042803///protein homodimerization activity",null,"uncharacterized LOC105369201","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369205,"'LOC105369205'",65,76,55,65.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"uncharacterized LOC105369205","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369214,"'LOC105369214'",1,2,0,1,{"$nulls":7},"uncharacterized LOC105369214","[Q9H5V2_HUMAN|Unreviewed]SubName: Full=cDNA: FLJ23003 fis, clone LNG00331 {ECO:0000313|EMBL:BAB15517.1};"]
[105369246,"'LOC105369246'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC105369246","[Q6ZT72_HUMAN|diamond]SubName: Full=cDNA FLJ44904 fis, clone BRAMY3005656 {ECO:0000313|EMBL:BAC86722.1};"]
[105369669,"'LOC105369669'",0,0,1,0.333333333333333,"04217///Necroptosis+++05034///Alcoholism+++04137///Mitophagy - animal+++05322///Systemic lupus erythematosus+++04140///Autophagy - animal",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006352///DNA-templated transcription, initiation+++GO:0006342///chromatin silencing+++GO:0006334///nucleosome assembly","uncharacterized LOC105369669","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[H2AJ_BOVIN|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_HUMAN|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_MACFA|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_MOUSE|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_RAT|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H4_HUMAN|diamond]RecName: Full=Histone H4;+++[H4_MACFA|diamond]RecName: Full=Histone H4;+++[H4_PONAB|diamond]RecName: Full=Histone H4;+++[H4_URECA|diamond]RecName: Full=Histone H4;+++[H4_XENTR|diamond]RecName: Full=Histone H4;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369869,"'LOC105369869'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0043005///neuron projection+++GO:0098793///presynapse+++GO:0070062///extracellular exosome+++GO:0045211///postsynaptic membrane+++GO:0045202///synapse+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0005923///bicellular tight junction+++GO:0005622///intracellular","GO:0097016///L27 domain binding","GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0048489///synaptic vesicle transport+++GO:0048839///inner ear development+++GO:0007269///neurotransmitter secretion+++GO:1903361///protein localization to basolateral plasma membrane+++GO:0065003///protein-containing complex assembly+++GO:0006887///exocytosis+++GO:0015031///protein transport","uncharacterized LOC105369869","[LIN7A_BOVIN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A;+++[LIN7A_HUMAN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=hLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Tax interaction protein 33; Short=TIP-33; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_MOUSE|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=mLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_RAT|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;"]
[105369914,"'LOC105369914'",1,2,2,1.66666666666667,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","translation initiation factor IF-2-like","[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[PKP2_HUMAN|diamond]RecName: Full=Plakophilin-2;+++[TMCC1_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 1;+++[TMCC2_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 2; AltName: Full=Cerebral protein 11;+++[TMCC2_MOUSE|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 2;+++[TMCC3_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domain protein 3;+++[TMCC3_MOUSE|diamond]RecName: Full=Transmembrane and coiled-coil domain protein 3;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[10537,"'UBD'",0,1,4,1.66666666666667,{"$nulls":4},"GO:0016235///aggresome+++GO:0045211///postsynaptic membrane+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0030054///cell junction+++GO:0098793///presynapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0038037///G protein-coupled receptor dimeric complex+++GO:0038039///G protein-coupled receptor heterodimeric complex+++GO:0042734///presynaptic membrane+++GO:0016020///membrane+++GO:0098982///GABA-ergic synapse+++GO:0005737///cytoplasm","GO:0099579///G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential+++GO:0005515///protein binding+++GO:0070628///proteasome binding+++GO:0004965///G protein-coupled GABA receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0006508///proteolysis+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0032446///protein modification by small protein conjugation+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016567///protein ubiquitination+++GO:0034341///response to interferon-gamma+++GO:0043687///post-translational protein modification+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070842///aggresome assembly+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0034612///response to tumor necrosis factor+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","ubiquitin D","[UBD_HUMAN|Reviewed]RecName: Full=Ubiquitin D; AltName: Full=Diubiquitin; AltName: Full=Ubiquitin-like protein FAT10;+++[A0A0G2JH67_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77196.1}; SubName: Full=Ubiquitin D {ECO:0000313|Ensembl:ENSP00000373137};+++[A0A0G2JKF9_HUMAN|Unreviewed]SubName: Full=GABBR1 {ECO:0000313|EMBL:AQY76823.1}; SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000416731};+++[A0A140T9S4_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000412044};+++[A0A140TA42_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000448763};+++[A0A1U9X8S6_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77194.1};+++[C9J342_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417332}; Flags: Fragment;+++[C9JZG6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419755}; Flags: Fragment;+++[F8WAS6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417663};+++[F8WAV2_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417478};+++[F8WDC0_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000420602};+++[F8WF38_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419356};"]
[105370045,"'105370045'",80,61,48,63,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding","GO:0061572///actin filament bundle organization+++GO:0061181///regulation of chondrocyte development",null,"[RFLA_HUMAN|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;+++[RFLA_MOUSE|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A {ECO:0000303|PubMed:21709252}; Short=RefilinA;"]
[105370092,"'LOC105370092'",5,3,15,7.66666666666667,{"$nulls":7},"uncharacterized LOC105370092","[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;"]
[105370378,"'LOC105370378'",0,0,1,0.333333333333333,{"$nulls":7},"MAGE-like protein 2","[A0A093GJ03_DRYPU|diamond]SubName: Full=Collagen alpha-1(IV) chain {ECO:0000313|EMBL:KFV69218.1}; Flags: Fragment;+++[A0A1S3QEZ2_SALSA|diamond]SubName: Full=adhesive plaque matrix protein-like {ECO:0000313|RefSeq:XP_014038407.1};+++[A0A210PMZ5_MIZYE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OWF37869.1};+++[A0A2G8JIE8_STIJA|diamond]SubName: Full=Repetitive proline-rich cell wall protein 2 {ECO:0000313|EMBL:PIK35488.1};+++[H0XUN6_OTOGA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSOGAP00000019828};+++[U3KDA5_FICAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000013009};"]
[105370399,"'LOC105370399'",0,3,3,2,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"uncharacterized LOC105370399","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370579,"'LOC105370579'",5,1,0,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC105370579","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370641,"'LOC105370641'",0,1,3,1.33333333333333,{"$nulls":7},"uncharacterized LOC105370641","[A0A146R4I4_FUNHE|diamond]SubName: Full=HCG1778991 {ECO:0000313|EMBL:JAQ63352.1}; Flags: Fragment;+++[A0A287ANQ5_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000045530};+++[A0A287BB99_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000053389};+++[A0A2G8KAB5_STIJA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PIK44956.1};+++[L8IFV1_9CETA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELR54012.1}; Flags: Fragment;"]
[105370687,"'LOC105370687'",20,23,21.9,21.6333333333333,"03013///RNA transport+++04214///Apoptosis - fly",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0008135///translation factor activity, RNA binding+++GO:0045296///cadherin binding+++GO:0003924///GTPase activity+++GO:0071074///eukaryotic initiation factor eIF2 binding+++GO:0003723///RNA binding+++GO:0005525///GTP binding+++GO:0003743///translation initiation factor activity","GO:0006446///regulation of translational initiation+++GO:0001731///formation of translation preinitiation complex+++GO:0006413///translational initiation+++GO:0090630///activation of GTPase activity","uncharacterized LOC105370687","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[IF5_DROME|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_HUMAN|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_MOUSE|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_PONAB|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_RAT|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370705,"'LOC105370705'",3,1,0,1.33333333333333,"03015///mRNA surveillance pathway+++03013///RNA transport+++03040///Spliceosome",null,"M00430///Exon junction complex (EJC)",null,"GO:0061574///ASAP complex+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0019899///enzyme binding+++GO:0003676///nucleic acid binding+++GO:0016887///ATPase activity+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0030218///erythrocyte differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0030263///apoptotic chromosome condensation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0045657///positive regulation of monocyte differentiation+++GO:0006397///mRNA processing","collagen alpha-2(I) chain-like","[ACINU_HUMAN|diamond]RecName: Full=Apoptotic chromatin condensation inducer in the nucleus; Short=Acinus;+++[ACINU_MOUSE|diamond]RecName: Full=Apoptotic chromatin condensation inducer in the nucleus; Short=Acinus;+++[CN119_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf119;+++[CN119_MOUSE|diamond]RecName: Full=Uncharacterized protein C14orf119 homolog;+++[LMLN2_HUMAN|diamond]RecName: Full=Leishmanolysin-like peptidase 2 {ECO:0000305}; EC=3.4.24.- {ECO:0000250|UniProtKB:Q9VH19}; Flags: Precursor;"]
[105370708,"'LOC105370708'",3,1,0,1.33333333333333,{"$nulls":7},"uncharacterized LOC105370708"]
[105370748,"'105370748'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0072686///mitotic spindle+++GO:0032580///Golgi cisterna membrane+++GO:0000922///spindle pole+++GO:0000139///Golgi membrane+++GO:0000137///Golgi cis cisterna+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0005794///Golgi apparatus","GO:0045296///cadherin binding+++GO:0019905///syntaxin binding+++GO:0042802///identical protein binding+++GO:0061676///importin-alpha family protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding","GO:0051289///protein homotetramerization+++GO:0090307///mitotic spindle assembly+++GO:0007098///centrosome cycle+++GO:0006486///protein glycosylation+++GO:0010507///negative regulation of autophagy+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0008356///asymmetric cell division+++GO:0060050///positive regulation of protein glycosylation+++GO:0032091///negative regulation of protein binding+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0051225///spindle assembly+++GO:0007020///microtubule nucleation+++GO:0048208///COPII vesicle coating+++GO:0090161///Golgi ribbon formation+++GO:0090306///spindle assembly involved in meiosis+++GO:0090166///Golgi disassembly",null,"[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[GOGA2_MOUSE|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein; Short=GM130 {ECO:0000303|PubMed:21552007, ECO:0000303|PubMed:26165940};+++[GOGA2_RAT|diamond]RecName: Full=Golgin subfamily A member 2 {ECO:0000305}; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8557739}; Short=GM130 {ECO:0000303|PubMed:8557739};"]
[105370849,"'LOC105370849'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0000137///Golgi cis cisterna+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0000139///Golgi membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0000922///spindle pole+++GO:0072686///mitotic spindle+++GO:0032580///Golgi cisterna membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane","GO:0019905///syntaxin binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0019901///protein kinase binding+++GO:0045296///cadherin binding+++GO:0061676///importin-alpha family protein binding","GO:0090166///Golgi disassembly+++GO:0010507///negative regulation of autophagy+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0051289///protein homotetramerization+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048208///COPII vesicle coating+++GO:0060050///positive regulation of protein glycosylation+++GO:0006486///protein glycosylation+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0007020///microtubule nucleation+++GO:0090306///spindle assembly involved in meiosis+++GO:0032091///negative regulation of protein binding+++GO:0008356///asymmetric cell division+++GO:0090161///Golgi ribbon formation+++GO:0090307///mitotic spindle assembly","golgin subfamily A member 2-like","[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8A; AltName: Full=88 kDa Golgi matrix protein; Short=GM88; AltName: Full=GM88 autoantigen;+++[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[GOGA2_MOUSE|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein; Short=GM130 {ECO:0000303|PubMed:21552007, ECO:0000303|PubMed:26165940};+++[GOGA2_RAT|diamond]RecName: Full=Golgin subfamily A member 2 {ECO:0000305}; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8557739}; Short=GM130 {ECO:0000303|PubMed:8557739};+++[YO027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ45275, mitochondrial; Flags: Precursor;"]
[105371095,"'LOC105371095'",0,1,0,0.333333333333333,{"$nulls":7},"collagen alpha-3(IX) chain-like","[PAWR_HUMAN|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_MOUSE|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_RAT|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4; AltName: Full=Transcriptional repressor Par-4-like protein PAWR;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;"]
[105371215,"'LOC105371215'",1,0,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC105371215"]
[105371448,"'LOC105371448'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070876///SOSS complex+++GO:0005887///integral component of plasma membrane",null,"GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0050885///neuromuscular process controlling balance+++GO:0007093///mitotic cell cycle checkpoint+++GO:0006281///DNA repair","uncharacterized LOC105371448","[IGDC3_HUMAN|diamond]RecName: Full=Immunoglobulin superfamily DCC subclass member 3; AltName: Full=Putative neuronal cell adhesion molecule; Flags: Precursor;+++[IGDC3_MOUSE|diamond]RecName: Full=Immunoglobulin superfamily DCC subclass member 3; AltName: Full=Putative neuronal cell adhesion molecule; Flags: Precursor;+++[INT3_DANRE|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[INT3_DROGR|diamond]RecName: Full=Integrator complex subunit 3 homolog; AltName: Full=SOSS complex subunit A homolog;+++[INT3_HUMAN|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[INT3_MOUSE|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[INT3_PONAB|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[PRTGA_DANRE|diamond]RecName: Full=Protogenin A; Flags: Precursor;+++[PRTGB_DANRE|diamond]RecName: Full=Protogenin B; Flags: Precursor; Fragment;+++[PRTG_CHICK|diamond]RecName: Full=Protogenin; Flags: Precursor;"]
[105371566,"'LOC105371566'",1,0,4,1.66666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0016459///myosin complex+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0032420///stereocilium","GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0046872///metal ion binding+++GO:0003774///motor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0005524///ATP binding+++GO:0005516///calmodulin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0042472///inner ear morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007626///locomotory behavior+++GO:0006351///transcription, DNA-templated+++GO:0007605///sensory perception of sound","uncharacterized LOC105371566","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[MYO15_HUMAN|diamond]RecName: Full=Unconventional myosin-XV; AltName: Full=Unconventional myosin-15;+++[PKP2_HUMAN|diamond]RecName: Full=Plakophilin-2;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN429_HUMAN|diamond]RecName: Full=Zinc finger protein 429;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105371763,"'LOC105371763'",18,22,20,20,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0035812///renal sodium excretion+++GO:2001161///negative regulation of histone H3-K79 methylation+++GO:0035811///negative regulation of urine volume+++GO:0010765///positive regulation of sodium ion transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036359///renal potassium excretion","uncharacterized LOC105371763","[AF10_HUMAN|diamond]RecName: Full=Protein AF-10 {ECO:0000305}; AltName: Full=ALL1-fused gene from chromosome 10 protein;+++[AF10_MOUSE|diamond]RecName: Full=Protein AF-10 {ECO:0000305};+++[AF17_HUMAN|diamond]RecName: Full=Protein AF-17; AltName: Full=ALL1-fused gene from chromosome 17 protein;+++[CISD3_HUMAN|diamond]RecName: Full=CDGSH iron-sulfur domain-containing protein 3, mitochondrial; AltName: Full=MitoNEET-related protein 2; Short=Miner2; AltName: Full=Mitochondrial inner NEET protein {ECO:0000303|PubMed:29259115}; Short=MiNT {ECO:0000303|PubMed:29259115}; Flags: Precursor;+++[YM2A_CAEEL|diamond]RecName: Full=Uncharacterized protein F54F2.2, isoform a;"]
[105371910,"'LOC105371910'",7,3,30,13.3333333333333,{"$nulls":4},"GO:0005829///cytosol","GO:0008732///L-allo-threonine aldolase activity","GO:0006545///glycine biosynthetic process+++GO:0006567///threonine catabolic process","uncharacterized LOC105371910","[A0A2U3XS95_LEPWE|diamond]SubName: Full=uncharacterized protein R102.4-like {ECO:0000313|RefSeq:XP_006734331.1};+++[A0A2Y9GBZ0_NEOSC|diamond]SubName: Full=probable low-specificity L-threonine aldolase 2 {ECO:0000313|RefSeq:XP_021536492.1};+++[F7D9Y6_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000005176};+++[G1M5J9_AILME|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000014617};+++[S9XGI9_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY86794.1};"]
[105371921,"'LOC105371921'",2,1,1,1.33333333333333,{"$nulls":7},"uncharacterized LOC105371921"]
[105371932,"'LOC105371932'",4,9,8,7,{"$nulls":4},"GO:0005634///nucleus","GO:0005524///ATP binding",null,"uncharacterized LOC105371932","[A0A2K5WEY0_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000035670};+++[A0A2K6C0W4_MACNE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000017314};"]
[105372269,"'LOC105372269'",2,1,1,1.33333333333333,{"$nulls":4},"GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004856///xylulokinase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004190///aspartic-type endopeptidase activity","GO:0042732///D-xylose metabolic process+++GO:0016032///viral process+++GO:0005997///xylulose metabolic process","endogenous retrovirus group K member 8 Gag polyprotein-like","[EN113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Env polyprotein; AltName: Full=EnvK5 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Env polyprotein; AltName: Full=EnvK3 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C19) envelope protein; AltName: Full=HERV-K_19q11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K_11q22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Env polyprotein; AltName: Full=EnvK2 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C7) envelope protein; AltName: Full=HERV-K(HML-2.HOM) envelope protein; AltName: Full=HERV-K108 envelope protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Env polyprotein; AltName: Full=EnvK6 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K115 envelope protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[GAK21_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 21 Gag polyprotein; AltName: Full=HERV-K_12q14.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[VP113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pro protein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[VPK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pro protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[XYLB_PONAB|diamond]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;"]
[105372315,"'LOC105372315'",5,6,4,5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane",null,null,"endogenous retrovirus group S71 member 1 Env polyprotein","[ENVT1_HUMAN|Reviewed]RecName: Full=Endogenous retrovirus group S71 member 1 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-T Env protein; AltName: Full=HERV-T_19q13.11 provirus ancestral Env polyprotein; Includes: RecName: Full=Surface protein; Short=SU; Includes: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[105372412,"'LOC105372412'",1,0,5,2,{"$nulls":7},"phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein-like","[A0A091DT05_FUKDA|diamond]SubName: Full=Interferon-inducible GTPase 5 {ECO:0000313|EMBL:KFO33613.1};+++[A0A2Y9P5V2_DELLE|diamond]SubName: Full=uncharacterized protein LOC111180525 {ECO:0000313|RefSeq:XP_022440616.1};+++[L9L7Y3_TUPCH|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELW71071.1};+++[M3Y5G8_MUSPF|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMPUP00000006569};+++[Q8WYX9_HUMAN|diamond]SubName: Full=Uncharacterized protein pp10122 {ECO:0000313|EMBL:AAL55824.1};+++[S9YW18_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY88250.1};"]
[105372704,"'LOC105372704'",2,0,2,1.33333333333333,{"$nulls":7},"uncharacterized LOC105372704"]
[105372798,"'LOC105372798'",2,0,0,0.666666666666667,null,"H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0097014///ciliary plasm+++GO:0036064///ciliary basal body+++GO:0035253///ciliary rootlet+++GO:0035869///ciliary transition zone","GO:0030145///manganese ion binding+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0000278///mitotic cell cycle+++GO:1900062///regulation of replicative cell aging+++GO:0006468///protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0007346///regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:2000772///regulation of cellular senescence+++GO:0032147///activation of protein kinase activity+++GO:0023014///signal transduction by protein phosphorylation","uncharacterized LOC105372798","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[FTM_HUMAN|diamond]RecName: Full=Protein fantom; AltName: Full=Nephrocystin-8; AltName: Full=RPGR-interacting protein 1-like protein; Short=RPGRIP1-like protein;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[NEK4_HUMAN|diamond]RecName: Full=Serine/threonine-protein kinase Nek4; EC=2.7.11.1 {ECO:0000250|UniProtKB:Q9Z1J2}; AltName: Full=Never in mitosis A-related kinase 4; Short=NimA-related protein kinase 4; AltName: Full=Serine/threonine-protein kinase 2; AltName: Full=Serine/threonine-protein kinase NRK2;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;"]
[105372824,"'LOC105372824'",2,11,16,9.66666666666667,{"$nulls":7},"uncharacterized LOC105372824","[A0A0B4J2C9_HUMAN|Unreviewed]SubName: Full=Pyridoxal kinase {ECO:0000313|Ensembl:ENSP00000479315};"]
[105372836,"'LOC105372836'",0,4,0,1.33333333333333,{"$nulls":7},"uncharacterized LOC105372836"]
[105372883,"'LOC105372883'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC105372883"]
[105372978,"'LINC01638'",7.01,4,2,4.33666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","long intergenic non-protein coding RNA 1638","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105373057,"'LOC105373057'",1,0,0,0.333333333333333,{"$nulls":7},"DNA-directed RNA polymerase II subunit RPB1-like","[A0A1S3PD37_SALSA|diamond]SubName: Full=uncharacterized protein LOC106584621 isoform X2 {ECO:0000313|RefSeq:XP_014025583.1};+++[A0A1S3PD96_SALSA|diamond]SubName: Full=uncharacterized protein LOC106584621 isoform X1 {ECO:0000313|RefSeq:XP_014025582.1};+++[A0A1U7SCQ5_ALLSI|diamond]SubName: Full=immediate early response 3-interacting protein 1 {ECO:0000313|RefSeq:XP_006038989.1};+++[A0A2A6CG39_PRIPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PDM77048.1}; Flags: Fragment;+++[U3JE66_FICAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000001070};"]
[105373091,"'LOC105373091'",1,3,0,1.33333333333333,{"$nulls":7},"atherin-like"]
[105373102,"'LOC105373102'",22,20,29,23.6666666666667,"05166///HTLV-I infection+++04022///cGMP-PKG signaling pathway+++04020///Calcium signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04218///Cellular senescence+++04217///Necroptosis+++05016///Huntington's disease+++05012///Parkinson's disease","H01118///Progressive external ophthalmoplegia (PEO)+++H00469///Mitochondrial DNA depletion syndrome (MDS)",null,null,"GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane","GO:0008171///O-methyltransferase activity+++GO:0015207///adenine transmembrane transporter activity+++GO:0051213///dioxygenase activity+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0005471///ATP:ADP antiporter activity+++GO:0046872///metal ion binding","GO:0006626///protein targeting to mitochondrion+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0050796///regulation of insulin secretion+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0046732///active induction of host immune response by virus","uncharacterized LOC105373102","[ADT2_BOVIN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_HUMAN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=ADP,ATP carrier protein, fibroblast isoform; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_PONAB|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT3_BOVIN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_HUMAN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_PIG|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ASML_HUMAN|diamond]RecName: Full=N-acetylserotonin O-methyltransferase-like protein; Short=ASMTL; EC=2.1.1.-;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105373154,"'LOC105373154'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005912///adherens junction+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane","GO:0003824///catalytic activity","GO:0007165///signal transduction","myosin heavy chain IB-like","[LANC3_HUMAN|diamond]RecName: Full=LanC-like protein 3;+++[LANC3_MOUSE|diamond]RecName: Full=LanC-like protein 3;+++[TMM47_BOVIN|diamond]RecName: Full=Transmembrane protein 47; AltName: Full=Transmembrane 4 superfamily member 10;+++[TMM47_CANLF|diamond]RecName: Full=Transmembrane protein 47; AltName: Full=Brain cell membrane protein 1; AltName: Full=Transmembrane 4 superfamily member 10;+++[TMM47_DANRE|diamond]RecName: Full=Transmembrane protein 47; AltName: Full=Transmembrane 4 superfamily member 10;+++[TMM47_HUMAN|diamond]RecName: Full=Transmembrane protein 47; AltName: Full=Brain cell membrane protein 1; AltName: Full=Transmembrane 4 superfamily member 10;+++[TMM47_MOUSE|diamond]RecName: Full=Transmembrane protein 47; AltName: Full=Transmembrane 4 superfamily member 10;+++[TMM47_XENTR|diamond]RecName: Full=Transmembrane protein 47; AltName: Full=Transmembrane 4 superfamily member 10;"]
[105373244,"'LOC105373244'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0030027///lamellipodium","GO:0047394///glycerophosphoinositol inositolphosphodiesterase activity+++GO:0046872///metal ion binding+++GO:0008889///glycerophosphodiester phosphodiesterase activity","GO:0006629///lipid metabolic process+++GO:0090527///actin filament reorganization+++GO:0045669///positive regulation of osteoblast differentiation","uncharacterized LOC105373244","[GDPD2_HUMAN|diamond]RecName: Full=Glycerophosphoinositol inositolphosphodiesterase GDPD2; EC=3.1.4.43; AltName: Full=Glycerophosphodiester phosphodiesterase 3; AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 2; AltName: Full=Osteoblast differentiation promoting factor;+++[GDPD2_MOUSE|diamond]RecName: Full=Glycerophosphoinositol inositolphosphodiesterase GDPD2; EC=3.1.4.43; AltName: Full=Glycerophosphodiester phosphodiesterase 3; AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 2; AltName: Full=Osteoblast differentiation promoting factor;+++[GDPD5_CHICK|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;+++[GDPD5_HUMAN|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;+++[GDPD5_MOUSE|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;"]
[105373289,"'LOC105373289'",4,0,2,2,{"$nulls":7},"collagen alpha-1(III) chain-like"]
[105373311,"'LOC105373311'",131,115,106,117.333333333333,{"$nulls":7},"translation initiation factor IF-2","[A0A1S3WQD2_ERIEU|diamond]SubName: Full=uncharacterized protein LOC107523152 {ECO:0000313|RefSeq:XP_016048578.1};+++[A0A2Y9FXY4_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC101348364 {ECO:0000313|RefSeq:XP_012411968.1};+++[A0A2Y9LSY7_DELLE|diamond]SubName: Full=LOW QUALITY PROTEIN: transcription factor Maf {ECO:0000313|RefSeq:XP_022412460.1};+++[B7Z208_HUMAN|diamond]SubName: Full=cDNA FLJ52622 {ECO:0000313|EMBL:BAH11694.1};"]
[105373314,"'LOC105373314'",3,1,0,1.33333333333333,{"$nulls":4},"GO:0005881///cytoplasmic microtubule+++GO:0043209///myelin sheath+++GO:0055037///recycling endosome+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0031594///neuromuscular junction","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton","GO:0007017///microtubule-based process+++GO:0050807///regulation of synapse organization","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1","[B3GNL_HUMAN|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-; AltName: Full=Beta-1,3-N-acetylglucosaminyltransferase 8; Short=BGnT-8; Short=Beta-1,3-Gn-T8; Short=Beta3Gn-T8;+++[B3GNL_MOUSE|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-;+++[B3GNL_RAT|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-;+++[TBA1A_CRIGR|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 2; AltName: Full=Alpha-tubulin II; AltName: Full=Tubulin alpha-2 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_MOUSE|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_PANTR|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 3; AltName: Full=Tubulin B-alpha-1; AltName: Full=Tubulin alpha-3 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_RAT|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Tubulin alpha-1 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA_BOMMO|diamond]RecName: Full=Tubulin alpha chain;"]
[105373381,"'LOC105373381'",0,1,0,0.333333333333333,{"$nulls":7},"extracellular matrix protein 2","[ECM2_BOVIN|diamond]RecName: Full=Extracellular matrix protein 2; Flags: Precursor;+++[ECM2_HUMAN|diamond]RecName: Full=Extracellular matrix protein 2; AltName: Full=Matrix glycoprotein SC1/ECM2; Flags: Precursor;+++[ECM2_MOUSE|diamond]RecName: Full=Extracellular matrix protein 2; AltName: Full=Tenonectin; Flags: Precursor;+++[PGS2_MOUSE|diamond]RecName: Full=Decorin; AltName: Full=Bone proteoglycan II; AltName: Full=PG-S2; AltName: Full=PG40; Flags: Precursor;+++[PGS2_RAT|diamond]RecName: Full=Decorin; AltName: Full=Bone proteoglycan II; AltName: Full=Dermatan sulfate proteoglycan-II; Short=DSPG; AltName: Full=PG-S2; AltName: Full=PG40; Flags: Precursor;"]
[105373759,"'LOC105373759'",1,2.97,4,2.65666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","uncharacterized LOC105373759","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105373780,"'LOC105373780'",3,2,3,2.66666666666667,{"$nulls":7},"proline-rich protein 18-like"]
[105373944,"'LOC105373944'",0,1,1,0.666666666666667,{"$nulls":7},"translation initiation factor IF-2-like","[A0A2U3ZY91_ODORO|diamond]SubName: Full=collagen alpha-1(I) chain-like {ECO:0000313|RefSeq:XP_012423953.1};"]
[105373989,"'LOC105373989'",23,32,25,26.6666666666667,"04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery","GO:0005125///cytokine activity+++GO:0046789///host cell surface receptor binding+++GO:0005179///hormone activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0042803///protein homodimerization activity+++GO:0008083///growth factor activity","GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0042981///regulation of apoptotic process+++GO:0009267///cellular response to starvation+++GO:0030154///cell differentiation+++GO:0006952///defense response+++GO:0046676///negative regulation of insulin secretion+++GO:0048178///negative regulation of hepatocyte growth factor biosynthetic process+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0032924///activin receptor signaling pathway+++GO:0001541///ovarian follicle development+++GO:0045444///fat cell differentiation+++GO:0009611///response to wounding+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0048468///cell development+++GO:0043408///regulation of MAPK cascade+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0060279///positive regulation of ovulation+++GO:0044320///cellular response to leptin stimulus+++GO:0032869///cellular response to insulin stimulus+++GO:0048599///oocyte development","putative cuticle collagen 91","[INHBB_BOVIN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_HUMAN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_MOUSE|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_PIG|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_RAT|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;"]
[105374013,"'LOC105374013'",17,13,13,14.3333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0042788///polysomal ribosome","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044183///protein binding involved in protein folding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0042803///protein homodimerization activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0005198///structural molecule activity+++GO:0003676///nucleic acid binding","GO:0006915///apoptotic process+++GO:0002181///cytoplasmic translation+++GO:0010458///exit from mitosis+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0006310///DNA recombination+++GO:0016032///viral process+++GO:0021554///optic nerve development+++GO:0007093///mitotic cell cycle checkpoint+++GO:0015074///DNA integration+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0000027///ribosomal large subunit assembly+++GO:0006351///transcription, DNA-templated+++GO:0008616///queuosine biosynthetic process+++GO:0060041///retina development in camera-type eye","endogenous retrovirus group K member 5 Gag polyprotein","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GA113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Gag polyprotein; AltName: Full=HERV-K113 Gag protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Gag polyprotein; AltName: Full=HERV-K101 Gag protein; AltName: Full=HERV-K_22q11.21 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Gag polyprotein; AltName: Full=HERV-K(C7) Gag protein; AltName: Full=HERV-K(HML-2.HOM) Gag protein; AltName: Full=HERV-K108 Gag protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[PDCL3_BOVIN|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_HUMAN|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=HTPHLP; AltName: Full=PhPL3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_MOUSE|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_PONAB|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_RAT|diamond]RecName: Full=Phosducin-like protein 3;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Pol protein; AltName: Full=HERV-K(III) Pol protein; AltName: Full=HERV-K102 Pol protein; AltName: Full=HERV-K_1q22 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[RL24_BOVIN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_FELCA|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_HUMAN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=60S ribosomal protein L30; AltName: Full=Large ribosomal subunit protein eL24 {ECO:0000303|PubMed:24524803};+++[RL24_MACFA|diamond]RecName: Full=60S ribosomal protein L24;+++[RL24_MOUSE|diamond]RecName: Full=60S ribosomal protein L24;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[ZBT11_HUMAN|diamond]RecName: Full=Zinc finger and BTB domain-containing protein 11;"]
[105374089,"'LOC105374089'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0031514///motile cilium+++GO:0097545///axonemal outer doublet","GO:0070840///dynein complex binding","GO:2000574///regulation of microtubule motor activity+++GO:0003341///cilium movement+++GO:0036159///inner dynein arm assembly","uncharacterized LOC105374089","[Q9NXP9_HUMAN|Unreviewed]SubName: Full=HCG1780190 {ECO:0000313|EMBL:EAW79365.1}; SubName: Full=cDNA FLJ20123 fis, clone COL06041 {ECO:0000313|EMBL:BAA90961.1};"]
[105374103,"'LOC105374103'",2.95,0.87,2.96,2.26,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity","GO:0015074///DNA integration","uncharacterized LOC105374103","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105374299,"'LOC105374299'",0,2,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"uncharacterized LOC105374299","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105374301,"'LOC105374301'",74,62,93,76.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005813///centrosome+++GO:0030289///protein phosphatase 4 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0019888///protein phosphatase regulator activity+++GO:0030674///protein binding, bridging","GO:0008380///RNA splicing+++GO:0006464///cellular protein modification process+++GO:0006397///mRNA processing+++GO:0010569///regulation of double-strand break repair via homologous recombination","mucin-1-like","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP4R2_CHICK|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_HUMAN|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_MOUSE|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_PONAB|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105374378,"'LOC105374378'",9,6,7,7.33333333333333,"00030///Pentose phosphate pathway+++03010///Ribosome",null,"M00178///Ribosome, bacteria","R02750///2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP+++R01051///ATP:D-ribose 5-phosphotransferase ATP + D-Ribose <=> ADP + D-Ribose 5-phosphate","GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit","GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0003735///structural constituent of ribosome+++GO:0019200///carbohydrate kinase activity+++GO:0004747///ribokinase activity","GO:0019303///D-ribose catabolic process+++GO:0070125///mitochondrial translational elongation+++GO:0046835///carbohydrate phosphorylation+++GO:0070126///mitochondrial translational termination+++GO:0006098///pentose-phosphate shunt","uncharacterized LOC105374378","[RBSK_HUMAN|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000269|PubMed:17585908};+++[RBSK_MOUSE|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000312|EMBL:AAH23339.1}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215};+++[RM33_ANOGA|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_BOVIN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_HUMAN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; AltName: Full=Mitochondrial large ribosomal subunit protein bL33m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[RM33_MOUSE|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_TETNG|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;"]
[105374811,"'LOC105374811'",3,0,2,1.66666666666667,"00230///Purine metabolism+++05166///HTLV-I infection+++00240///Pyrimidine metabolism+++03030///DNA replication+++03420///Nucleotide excision repair+++01100///Metabolic pathways+++03410///Base excision repair",null,"M00263///DNA polymerase epsilon complex","R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dTTP + DNA <=> Diphosphate + DNA+++R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dGTP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dCTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dATP + DNA <=> Diphosphate + DNA","GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0036126///sperm flagellum+++GO:0030425///dendrite+++GO:0061827///sperm head+++GO:0008622///epsilon DNA polymerase complex+++GO:0005886///plasma membrane+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0097225///sperm midpiece+++GO:0005654///nucleoplasm+++GO:0009986///cell surface+++GO:0044297///cell body","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0016496///substance P receptor activity+++GO:0046872///metal ion binding+++GO:0004995///tachykinin receptor activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046982///protein heterodimerization activity","GO:0002687///positive regulation of leukocyte migration+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0045777///positive regulation of blood pressure+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042713///sperm ejaculation+++GO:0007268///chemical synaptic transmission+++GO:0010193///response to ozone+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032197///transposition, RNA-mediated+++GO:0003051///angiotensin-mediated drinking behavior+++GO:0043117///positive regulation of vascular permeability+++GO:0045987///positive regulation of smooth muscle contraction+++GO:1902093///positive regulation of flagellated sperm motility+++GO:0007217///tachykinin receptor signaling pathway+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0045907///positive regulation of vasoconstriction+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0035094///response to nicotine+++GO:0035106///operant conditioning+++GO:0043966///histone H3 acetylation+++GO:0048266///behavioral response to pain+++GO:0045778///positive regulation of ossification+++GO:0009582///detection of abiotic stimulus+++GO:0032570///response to progesterone+++GO:0045471///response to ethanol+++GO:0002118///aggressive behavior+++GO:0046878///positive regulation of saliva secretion+++GO:0046887///positive regulation of hormone secretion+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006954///inflammatory response+++GO:0010996///response to auditory stimulus+++GO:0043278///response to morphine+++GO:0045760///positive regulation of action potential+++GO:0007616///long-term memory+++GO:0051496///positive regulation of stress fiber assembly+++GO:0010634///positive regulation of epithelial cell migration+++GO:0009408///response to heat+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0051602///response to electrical stimulus+++GO:0019233///sensory perception of pain+++GO:0008306///associative learning+++GO:0002526///acute inflammatory response+++GO:0006310///DNA recombination+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042755///eating behavior+++GO:0032355///response to estradiol+++GO:0014910///regulation of smooth muscle cell migration","uncharacterized LOC105374811","[DPOE4_BOVIN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4;+++[DPOE4_HUMAN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[DPOE4_MOUSE|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NFYC_BOVIN|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NFYC_RAT|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=CCAAT-binding transcription factor subunit C; Short=CBF-C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NK1R_CANLF|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_CAVPO|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_HUMAN|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_MOUSE|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_RAT|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;"]
[105375106,"'LOC105375106'",1,0,0,0.333333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030027///lamellipodium",null,"GO:0030335///positive regulation of cell migration+++GO:2000813///negative regulation of barbed-end actin filament capping+++GO:0051638///barbed-end actin filament uncapping+++GO:1902745///positive regulation of lamellipodium organization","uncharacterized LOC105375106","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[105375355,"'UPK3B'",19282,20773,28678,22911,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++04330///Notch signaling pathway","H01439///Williams-Beuren syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0010629///negative regulation of gene expression","uroplakin 3B","[UPK3B_HUMAN|Reviewed]RecName: Full=Uroplakin-3b; Short=UP3b; AltName: Full=Uroplakin IIIb; Short=UPIIIb; AltName: Full=p35; Flags: Precursor;+++[A0A0J9YVS6_HUMAN|Unreviewed]SubName: Full=Uroplakin-3b {ECO:0000313|Ensembl:ENSP00000487650};"]
[105376204,"'LOC105376204'",5,4,6,5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC105376204","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376335,"'LOC105376335'",0,0,1,0.333333333333333,{"$nulls":7},"serine/arginine repetitive matrix protein 1-like"]
[105376353,"'LOC105376353'",16,12,26,18,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity",null,"mucin-5AC-like","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FTM_HUMAN|diamond]RecName: Full=Protein fantom; AltName: Full=Nephrocystin-8; AltName: Full=RPGR-interacting protein 1-like protein; Short=RPGRIP1-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105376525,"'LOC105376525'",1,0,2,1,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003824///catalytic activity","GO:0008152///metabolic process","ectonucleotide pyrophosphatase/phosphodiesterase family member 7-like","[ENPP7_HUMAN|diamond]RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; Short=E-NPP 7; Short=NPP-7; EC=3.1.4.12 {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774, ECO:0000269|PubMed:15205117, ECO:0000269|PubMed:28292932}; AltName: Full=Alkaline sphingomyelin phosphodiesterase; AltName: Full=Intestinal alkaline sphingomyelinase {ECO:0000303|PubMed:12671034, ECO:0000303|PubMed:12885774}; Short=Alk-SMase {ECO:0000303|PubMed:12885774, ECO:0000303|PubMed:28292932}; Flags: Precursor;+++[ENPP7_RAT|diamond]RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; Short=E-NPP 7; Short=NPP-7; EC=3.1.4.12 {ECO:0000269|PubMed:15708357}; AltName: Full=Alkaline sphingomyelin phosphodiesterase; AltName: Full=Intestinal alkaline sphingomyelinase; Short=Alk-SMase; Flags: Precursor;"]
[105376526,"'LOC105376526'",2,2,0,1.33333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0016021///integral component of membrane","GO:0003723///RNA binding","GO:0051028///mRNA transport","uncharacterized LOC105376526","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[ENR1_HUMAN|diamond]RecName: Full=Endogenous retrovirus group 3 member 1 Env polyprotein; AltName: Full=ERV-3 envelope protein; Short=ERV3 envelope protein; AltName: Full=ERV3-1 envelope protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-R envelope protein; Short=ERV-R envelope protein; AltName: Full=HERV-R_7q21.2 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ERK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Rec protein; AltName: Full=Endogenous retrovirus group K member 25; AltName: Full=HERV-K_11q22.1 provirus Rec protein;+++[POL1_MOUSE|diamond]RecName: Full=Retrovirus-related Pol polyprotein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; Flags: Fragment;+++[REC19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Rec protein; AltName: Full=HERV-K(C19) Rec protein; AltName: Full=HERV-K_19q11 provirus Rec protein;+++[REC6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Rec protein; AltName: Full=Central open reading frame; Short=c-orf; Short=cORF; AltName: Full=Endogenous retrovirus K protein 6; AltName: Full=HERV-K(C7) Rec protein; AltName: Full=HERV-K(HML-2.HOM) Rec protein; AltName: Full=HERV-K108 Rec protein; AltName: Full=HERV-K_7p22.1 provirus Rec protein; AltName: Full=K-Rev; AltName: Full=Rev-like protein; AltName: Full=Rev/Rex homolog;+++[REC9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Rec protein; AltName: Full=HERV-K(C6) Rec protein; AltName: Full=HERV-K109 Rec protein; AltName: Full=HERV-K_6q14.1 provirus Rec protein;+++[RECK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Rec protein; AltName: Full=HERV-K115 Rec protein; AltName: Full=HERV-K_8p23.1 provirus Rec protein;+++[SYCY2_CALJA|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PANTR|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PONPY|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ZMAT1_HUMAN|diamond]RecName: Full=Zinc finger matrin-type protein 1;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105376684,"'LOC105376684'",11.94,7,5,7.98,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"translation initiation factor IF-2-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376791,"'LOC105376791'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC105376791"]
[105376875,"'LOC105376875'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC105376875"]
[105376906,"'LOC105376906'",22.14,10.99,22.5,18.5433333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0015074///DNA integration","endogenous retrovirus group K member 19 Pol protein","[PO113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pol protein; AltName: Full=HERV-K113 Pol protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Pol protein; AltName: Full=HERV-K(C19) Pol protein; AltName: Full=HERV-K_19q11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;"]
[105376917,"'LOC105376917'",1,1,0,0.666666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0031093///platelet alpha granule lumen+++GO:0005576///extracellular region","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0008134///transcription factor binding","GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated+++GO:0002576///platelet degranulation+++GO:0048599///oocyte development","uncharacterized LOC105376917","[CE017_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C5orf17;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FIGLA_HUMAN|diamond]RecName: Full=Factor in the germline alpha; Short=FIGalpha; AltName: Full=Class C basic helix-loop-helix protein 8; Short=bHLHc8; AltName: Full=Folliculogenesis-specific basic helix-loop-helix protein; AltName: Full=Transcription factor FIGa;+++[FIGLA_MOUSE|diamond]RecName: Full=Factor in the germline alpha; Short=FIGalpha; AltName: Full=Transcription factor FIGa;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NR3L1_HUMAN|diamond]RecName: Full=Natural cytotoxicity triggering receptor 3 ligand 1; AltName: Full=B7 homolog 6; Short=B7-H6; Flags: Precursor;+++[NR3L1_PONAB|diamond]RecName: Full=Natural cytotoxicity triggering receptor 3 ligand 1; AltName: Full=B7 homolog 6; Short=B7-H6; Flags: Precursor;+++[TX264_HUMAN|diamond]RecName: Full=Testis-expressed protein 264; AltName: Full=Putative secreted protein Zsig11; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN431_HUMAN|diamond]RecName: Full=Zinc finger protein 431;+++[ZN492_HUMAN|diamond]RecName: Full=Zinc finger protein 492; AltName: Full=Zinc finger protein 115;+++[ZN730_HUMAN|diamond]RecName: Full=Putative zinc finger protein 730;+++[ZNF85_HUMAN|diamond]RecName: Full=Zinc finger protein 85; AltName: Full=Zinc finger protein HPF4; AltName: Full=Zinc finger protein HTF1;+++[ZNF98_HUMAN|diamond]RecName: Full=Zinc finger protein 98; AltName: Full=Zinc finger protein 739; AltName: Full=Zinc finger protein F7175;"]
[105377022,"'LOC105377022'",8,4,7,6.33333333333333,{"$nulls":7},"uncharacterized LOC105377022"]
[105377622,"'LOC105377622'",2,2,7,3.66666666666667,{"$nulls":7},"uncharacterized LOC105377622","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105377650,"'LOC105377650'",14,7,0,7,{"$nulls":7},"uncharacterized LOC105377650","[A0A1B0GRK0_MOUSE|diamond]SubName: Full=Predicted gene 45521 {ECO:0000313|Ensembl:ENSMUSP00000147554};+++[A0A2I2UDG9_FELCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000030524};+++[G3HFM3_CRIGR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGV92989.1};+++[L5K8U9_PTEAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELK07797.1};+++[S9WRC2_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY81017.1};"]
[105377777,"'LOC105377777'",2,0,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"uncharacterized LOC105377777","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105377792,"'LOC105377792'",0,1,0,0.333333333333333,{"$nulls":7},"protein app1-like","[A0A1L8GW49_XENLA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OCT88050.1}; Flags: Fragment;+++[A0A1S3RID8_SALSA|diamond]SubName: Full=extensin-like {ECO:0000313|RefSeq:XP_014051617.1};+++[S7PPG6_MYOBR|diamond]SubName: Full=Putative proline-rich protein 21 {ECO:0000313|EMBL:EPQ12738.1};+++[T1FL16_HELRO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESO00526.1, ECO:0000313|EnsemblMetazoa:HelroP184351};+++[W4ZHS9_STRPU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_027741-tr};"]
[105377805,"'LOC105377805'",6,4,7,5.66666666666667,{"$nulls":7},"basic salivary proline-rich protein 4-like","[A0A026VVN5_OOCBI|diamond]SubName: Full=F-box only protein {ECO:0000313|EMBL:EZA47853.1};+++[A0A060YYP9_ONCMY|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDQ96866.1}; Flags: Fragment;+++[A0A093I0R1_STRCA|diamond]SubName: Full=Putative proline-rich protein 21 {ECO:0000313|EMBL:KFV87521.1}; Flags: Fragment;+++[A0A099ZME2_TINGU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGL82088.1}; Flags: Fragment;+++[A0A2T7NET3_POMCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PVD19655.1};"]
[105378592,"'105378592'",1,2,8.8,3.93333333333333]
[105378803,"'LRRC53'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"leucine rich repeat containing 53","[LRC53_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 53;"]
[105378862,"'LOC105378862'",72,80,66,72.6666666666667,{"$nulls":7},"translation initiation factor IF-2-like","[F6VET6_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000009862};+++[F7DFZ3_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000012093};+++[F7DXK1_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000017383};"]
[105378947,"'LOC105378947'",0,0,1,0.333333333333333,{"$nulls":7},"proline-rich extensin-like protein EPR1","[E2BKF3_HARSA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFN83838.1};"]
[105378949,"'LOC105378949'",12,20,6,12.6666666666667,{"$nulls":7},"collagen alpha-2(VIII) chain"]
[105379045,"'105379045'",3,3,1,2.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":7},"[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379177,"'LOC105379177'",0,1.91,1.06,0.99,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"uncharacterized LOC105379177","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379198,"'LOC105379198'",0,0,3,1,{"$nulls":5},"GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination","uncharacterized LOC105379198","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[105379282,"'LOC105379282'",0,0,1,0.333333333333333,{"$nulls":7},"glucose-dependent insulinotropic receptor-like","[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;"]
[105379417,"'LOC105379417'",1,0,0,0.333333333333333,{"$nulls":7},"ankyrin repeat domain-containing protein 20A2-like","[A20A1_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 20A1;+++[A20A2_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 20A2;+++[A20A3_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 20A3;+++[A20A4_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 20A4;+++[AN20B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 20B; AltName: Full=Ankyrin repeat domain-containing protein 20A pseudogene;"]
[105379443,"'LOC105379443'",40.23,19.57,44.22,34.6733333333333,"04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal+++00670///One carbon pool by folate",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0016805///dipeptidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005524///ATP binding+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0008236///serine-type peptidase activity+++GO:0043565///sequence-specific DNA binding+++GO:0050129///N-formylglutamate deformylase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0004329///formate-tetrahydrofolate ligase activity","GO:0015942///formate metabolic process+++GO:0042135///neurotransmitter catabolic process+++GO:0046655///folic acid metabolic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0035999///tetrahydrofolate interconversion+++GO:0006760///folic acid-containing compound metabolic process+++GO:0001843///neural tube closure+++GO:0006351///transcription, DNA-templated+++GO:0009257///10-formyltetrahydrofolate biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0006310///DNA recombination+++GO:0006508///proteolysis+++GO:0048703///embryonic viscerocranium morphogenesis","monofunctional C1-tetrahydrofolate synthase, mitochondrial-like","[BEND2_HUMAN|diamond]RecName: Full=BEN domain-containing protein 2;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOXD4_HUMAN|diamond]RecName: Full=Forkhead box protein D4; AltName: Full=Forkhead-related protein FKHL9; AltName: Full=Forkhead-related transcription factor 5; Short=FREAC-5; AltName: Full=Myeloid factor-alpha;+++[FX4L3_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 3; Short=FOXD4-like 3;+++[FX4L4_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 4 {ECO:0000305}; Short=FOXD4-like 4 {ECO:0000305}; AltName: Full=Forkhead box protein D4-like 2 {ECO:0000312|HGNC:HGNC:23762}; AltName: Full=Forkhead box protein D4B {ECO:0000305|PubMed:12234674}; AltName: Full=Myeloid factor-gamma {ECO:0000312|EMBL:AAL73342.1};+++[FX4L5_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 5; Short=FOXD4-like 5;+++[FX4L6_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 6; Short=FOXD4-like 6;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379547,"'LOC105379547'",1,8,5,4.66666666666667,{"$nulls":7},"paraneoplastic antigen Ma6E-like","[A0A2I2YCC5_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000032450};+++[A0A2I2YHS6_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000034480};+++[A0A2I2Z815_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000043246};+++[A0A2I3ST96_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000080167};+++[A0A2I3TT44_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000092156};"]
[105379554,"'LOC105379554'",55.1,63,58.01,58.7033333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0036126///sperm flagellum+++GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0030317///flagellated sperm motility","maFF-interacting protein","[MAFIP_HUMAN|diamond]RecName: Full=MaFF-interacting protein; AltName: Full=Tektin-4 like protein PP5644;+++[TEKT4_BOVIN|diamond]RecName: Full=Tektin-4;+++[TEKT4_HUMAN|diamond]RecName: Full=Tektin-4;+++[TEKT4_MOUSE|diamond]RecName: Full=Tektin-4; AltName: Full=Testicular microtubules-related protein 4;+++[TEKT4_RAT|diamond]RecName: Full=Tektin-4;"]
[105379561,"'LOC105379561'",7,8.01,2,5.67,{"$nulls":7},"uncharacterized LOC105379561","[A0A0D9SCH2_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000018561};+++[A0A1A9ADJ3_9APIC|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:SBT54262.1};"]
[105379575,"'105379575'",3,1,2,2,{"$nulls":8},"[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A2_ASCSU|diamond]RecName: Full=Collagen alpha-2(IV) chain; Flags: Precursor;+++[CO4A2_CAEEL|diamond]RecName: Full=Collagen alpha-2(IV) chain; AltName: Full=Lethal protein 2; Flags: Precursor;+++[LWA_ANTEL|diamond]RecName: Full=LWamide neuropeptides; Contains: RecName: Full=LWamide I; Contains: RecName: Full=Metamorphosin A; Short=MMA; AltName: Full=LWamide II; Contains: RecName: Full=LWamide III; Contains: RecName: Full=LWamide IV; Contains: RecName: Full=LWamide V; Contains: RecName: Full=LWamide VI; Contains: RecName: Full=LWamide VII; Contains: RecName: Full=LWamide VIII; Contains: RecName: Full=LWamide IX; Flags: Precursor;+++[MUC2_HUMAN|diamond]RecName: Full=Mucin-2; Short=MUC-2; AltName: Full=Intestinal mucin-2; Flags: Precursor;"]
[105379752,"'LOC105379752'",0,1,4,1.66666666666667,{"$nulls":7},"uncharacterized LOC105379752","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[10539,"'GLRX3'",698,638,593,643,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005938///cell cortex+++GO:0030018///Z disc","GO:0009055///electron transfer activity+++GO:0003723///RNA binding+++GO:0015038///glutathione disulfide oxidoreductase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0051536///iron-sulfur cluster binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding","GO:0002026///regulation of the force of heart contraction+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0006879///cellular iron ion homeostasis+++GO:0022900///electron transport chain","glutaredoxin 3","[GLRX3_HUMAN|Reviewed]RecName: Full=Glutaredoxin-3; AltName: Full=PKC-interacting cousin of thioredoxin {ECO:0000303|PubMed:10636891}; Short=PICOT {ECO:0000303|PubMed:10636891}; AltName: Full=PKC-theta-interacting protein; Short=PKCq-interacting protein; AltName: Full=Thioredoxin-like protein 2;+++[A0A140VJK1_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 75 {ECO:0000313|EMBL:AEE60988.1};"]
[1054,"'CEBPG'",221,172,132,175,"05152///Tuberculosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity","GO:0042267///natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0001889///liver development+++GO:0016071///mRNA metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043353///enucleate erythrocyte differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0043388///positive regulation of DNA binding+++GO:0030183///B cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity","CCAAT enhancer binding protein gamma","[CEBPG_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein gamma; Short=C/EBP gamma;"]
[10540,"'DCTN2'",2440,2455,2330,2408.33333333333,"04962///Vasopressin-regulated water reabsorption+++05016///Huntington's disease",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0031982///vesicle+++GO:0005829///cytosol+++GO:0000776///kinetochore+++GO:0030426///growth cone+++GO:0005869///dynactin complex+++GO:0005813///centrosome+++GO:0030286///dynein complex+++GO:0016020///membrane","GO:0019901///protein kinase binding+++GO:0003774///motor activity+++GO:0030507///spectrin binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007017///microtubule-based process+++GO:0008283///cell proliferation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0071539///protein localization to centrosome+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007052///mitotic spindle organization+++GO:0032402///melanosome transport+++GO:0000086///G2/M transition of mitotic cell cycle","dynactin subunit 2","[DCTN2_HUMAN|Reviewed]RecName: Full=Dynactin subunit 2; AltName: Full=50 kDa dynein-associated polypeptide; AltName: Full=Dynactin complex 50 kDa subunit; Short=DCTN-50; AltName: Full=p50 dynamitin;+++[A8K8J9_HUMAN|Unreviewed]SubName: Full=Dynactin 2 (P50), isoform CRA_b {ECO:0000313|EMBL:EAW97028.1}; SubName: Full=cDNA FLJ31120 fis, clone IMR322000730, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG51555.1}; SubName: Full=cDNA FLJ77785 {ECO:0000313|EMBL:BAF85053.1};+++[B3KTX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38923 fis, clone NT2NE2011823, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG53236.1};+++[F8VRV7_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448606}; Flags: Fragment;+++[F8VW18_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449855}; Flags: Fragment;+++[F8VX93_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449710}; Flags: Fragment;+++[F8W0U6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447553};+++[F8W1I6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000446964};+++[H0YHL1_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447308}; Flags: Fragment;+++[H0YI98_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448937}; Flags: Fragment;+++[V9HW58_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 77 {ECO:0000313|EMBL:ACI46007.1};"]
[10541,"'ANP32B'",885,882,797,854.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0070063///RNA polymerase binding+++GO:0042393///histone binding+++GO:0005515///protein binding","GO:0046827///positive regulation of protein export from nucleus+++GO:0021591///ventricular system development+++GO:0001944///vasculature development+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0048839///inner ear development+++GO:0045596///negative regulation of cell differentiation+++GO:0006334///nucleosome assembly+++GO:0060021///roof of mouth development","acidic nuclear phosphoprotein 32 family member B","[AN32B_HUMAN|Reviewed]RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member B; AltName: Full=Acidic protein rich in leucines; AltName: Full=Putative HLA-DR-associated protein I-2; Short=PHAPI2; AltName: Full=Silver-stainable protein SSP29;"]
[10542,"'LAMTOR5'",382,435,388,401.666666666667,"05161///Hepatitis B+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0071986///Ragulator complex+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071230///cellular response to amino acid stimulus+++GO:0009615///response to virus+++GO:0043066///negative regulation of apoptotic process+++GO:0008361///regulation of cell size+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0061462///protein localization to lysosome+++GO:0007050///cell cycle arrest+++GO:0019079///viral genome replication","late endosomal/lysosomal adaptor, MAPK and MTOR activator 5","[LTOR5_HUMAN|Reviewed]RecName: Full=Ragulator complex protein LAMTOR5; AltName: Full=Hepatitis B virus X-interacting protein; Short=HBV X-interacting protein; Short=HBX-interacting protein; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5;+++[A0A0C4DGV4_HUMAN|Unreviewed]SubName: Full=Hepatitis B virus x interacting protein {ECO:0000313|EMBL:EAW56447.1}; SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000480529};+++[E9PLX3_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000435085};+++[R4GMU8_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000473357};"]
[10544,"'PROCR'",601,736,591,642.666666666667,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0038023///signaling receptor activity+++GO:0005515///protein binding","GO:0050819///negative regulation of coagulation+++GO:0007599///hemostasis+++GO:0007596///blood coagulation","protein C receptor","[EPCR_HUMAN|Reviewed]RecName: Full=Endothelial protein C receptor; AltName: Full=Activated protein C receptor; Short=APC receptor; AltName: Full=Endothelial cell protein C receptor; AltName: CD_antigen=CD201; Flags: Precursor;+++[A0A0U1RQQ4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489117}; Flags: Fragment;+++[A0A0U1RRC4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489456}; Flags: Fragment;"]
[10548,"'TM9SF1'",1855,1949,1834,1879.33333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0000421///autophagosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005764///lysosome+++GO:0016021///integral component of membrane",null,"GO:0072657///protein localization to membrane+++GO:0006914///autophagy","transmembrane 9 superfamily member 1","[TM9S1_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 1; AltName: Full=MP70 protein family member; Short=hMP70; Flags: Precursor;+++[B4E3A9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PJC4_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PJM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PL78_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PMQ9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PNW2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PP24_HUMAN|Unreviewed]SubName: Full=Transmembrane 9 superfamily member 1 {ECO:0000313|Ensembl:ENSP00000436486}; Flags: Fragment;+++[E9PQY7_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PS99_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[G3V1B9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[10549,"'PRDX4'",1556,1626,1420,1534,"04214///Apoptosis - fly",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0005623///cell+++GO:0005790///smooth endoplasmic reticulum+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0004601///peroxidase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0051920///peroxiredoxin activity+++GO:0016209///antioxidant activity+++GO:0008379///thioredoxin peroxidase activity","GO:0007252///I-kappaB phosphorylation+++GO:0045454///cell redox homeostasis+++GO:0072593///reactive oxygen species metabolic process+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification+++GO:0019471///4-hydroxyproline metabolic process+++GO:0006979///response to oxidative stress+++GO:2000255///negative regulation of male germ cell proliferation+++GO:0022417///protein maturation by protein folding+++GO:0008584///male gonad development+++GO:0043312///neutrophil degranulation+++GO:0007283///spermatogenesis+++GO:0055114///oxidation-reduction process+++GO:0030198///extracellular matrix organization","peroxiredoxin 4","[PRDX4_HUMAN|Reviewed]RecName: Full=Peroxiredoxin-4; EC=1.11.1.15 {ECO:0000269|PubMed:21916849, ECO:0000269|PubMed:9388242}; AltName: Full=Antioxidant enzyme AOE372; Short=AOE37-2; AltName: Full=Peroxiredoxin IV; Short=Prx-IV; AltName: Full=Thioredoxin peroxidase AO372; AltName: Full=Thioredoxin-dependent peroxide reductase A0372; Flags: Precursor;+++[A6NG45_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368635};+++[A6NJJ0_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368654}; Flags: Fragment;+++[H7C3T4_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000413736}; Flags: Fragment;+++[V9HW63_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 97n {ECO:0000313|EMBL:ACI45989.1}; SubName: Full=Peroxiredoxin 4 {ECO:0000313|EMBL:EAW98996.1};"]
[10550,"'ARL6IP5'",1949,1900,1722,1857,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0002037///negative regulation of L-glutamate import across plasma membrane+++GO:0015813///L-glutamate transmembrane transport+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential","ADP ribosylation factor like GTPase 6 interacting protein 5","[PRAF3_HUMAN|Reviewed]RecName: Full=PRA1 family protein 3; AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 5; Short=ARL-6-interacting protein 5; Short=Aip-5; AltName: Full=Cytoskeleton-related vitamin A-responsive protein; AltName: Full=Dermal papilla-derived protein 11; AltName: Full=GTRAP3-18; AltName: Full=Glutamate transporter EAAC1-interacting protein; AltName: Full=JM5; AltName: Full=Prenylated Rab acceptor protein 2; AltName: Full=Protein JWa; AltName: Full=Putative MAPK-activating protein PM27;+++[A0A024R371_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[C9JQU6_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF33_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF90_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10551,"'AGR2'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0042803///protein homodimerization activity+++GO:0002162///dystroglycan binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding","GO:0010628///positive regulation of gene expression+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:1903899///positive regulation of PERK-mediated unfolded protein response+++GO:0070254///mucus secretion+++GO:0034976///response to endoplasmic reticulum stress+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:0060480///lung goblet cell differentiation+++GO:0048639///positive regulation of developmental growth+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0060548///negative regulation of cell death+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0048546///digestive tract morphogenesis","anterior gradient 2, protein disulphide isomerase family member","[AGR2_HUMAN|Reviewed]RecName: Full=Anterior gradient protein 2 homolog; Short=AG-2; Short=hAG-2; AltName: Full=HPC8; AltName: Full=Secreted cement gland protein XAG-2 homolog; Flags: Precursor;+++[B5MC07_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000386025};+++[C9J3E2_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000411969}; Flags: Fragment;+++[H7C3Z9_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000414806}; Flags: Fragment;+++[Q4JM46_HUMAN|Unreviewed]SubName: Full=AGR2 {ECO:0000313|EMBL:AAY84774.1}; SubName: Full=Anterior gradient 2 homolog (Xenopus laevis) {ECO:0000313|EMBL:EAL24283.1}; SubName: Full=Anterior gradient 2 homolog (Xenopus laevis), isoform CRA_a {ECO:0000313|EMBL:EAW93682.1}; SubName: Full=Anterior gradient 2 splice variant C {ECO:0000313|EMBL:AJO53280.1}; SubName: Full=Epididymis secretory protein Li 116 {ECO:0000313|EMBL:ACI45999.1};+++[Q4JM47_HUMAN|Unreviewed]SubName: Full=AGR2 {ECO:0000313|EMBL:AAY84773.1};"]
[10552,"'ARPC1A'",1305,1361,1575,1413.66666666667,"05130///Pathogenic Escherichia coli infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++05131///Shigellosis",{"$nulls":3},"GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030833///regulation of actin filament polymerization+++GO:0061024///membrane organization","actin related protein 2/3 complex subunit 1A","[ARC1A_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1A; AltName: Full=SOP2-like protein;+++[A0A0K0K1L3_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 307 {ECO:0000313|EMBL:ACV87209.1}; Flags: Fragment;+++[E9PF58_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1A {ECO:0000313|Ensembl:ENSP00000408711};+++[Q75MY0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ARPC1A {ECO:0000313|EMBL:AAS00381.1}; Flags: Fragment;+++[V9HVZ6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};"]
[10553,"'HTATIP2'",128,148,133,136.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0045765///regulation of angiogenesis+++GO:0051170///import into nucleus+++GO:0030154///cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0016032///viral process+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development","HIV-1 Tat interactive protein 2","[HTAI2_HUMAN|Reviewed]RecName: Full=Oxidoreductase HTATIP2; EC=1.1.1.-; AltName: Full=30 kDa HIV-1 TAT-interacting protein; AltName: Full=HIV-1 TAT-interactive protein 2;+++[E9PI87_HUMAN|Unreviewed]SubName: Full=Oxidoreductase HTATIP2 {ECO:0000313|Ensembl:ENSP00000436729};"]
[10554,"'AGPAT1'",3778,4305,4197,4093.33333333333,"00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate+++R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0006629///lipid metabolic process+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0001819///positive regulation of cytokine production+++GO:0031325///positive regulation of cellular metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process","1-acylglycerol-3-phosphate O-acyltransferase 1","[PLCA_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 1; Short=1-AGP acyltransferase 1; Short=1-AGPAT 1; AltName: Full=Lysophosphatidic acid acyltransferase alpha; Short=LPAAT-alpha; AltName: Full=Protein G15; Flags: Precursor;+++[A0A024RCV5_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};"]
[10555,"'AGPAT2'",823,971,937,910.333333333333,"00564///Glycerophospholipid metabolism+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA+++R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0035579///specific granule membrane","GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity","GO:0042493///response to drug+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008544///epidermis development+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0001819///positive regulation of cytokine production+++GO:0043312///neutrophil degranulation+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","1-acylglycerol-3-phosphate O-acyltransferase 2","[PLCB_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase beta; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2; Short=1-AGP acyltransferase 2; Short=1-AGPAT 2; AltName: Full=Lysophosphatidic acid acyltransferase beta; Short=LPAAT-beta; Flags: Precursor;+++[A0A024R8F9_HUMAN|Unreviewed]SubName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2 (Lysophosphatidic acid acyltransferase, beta), isoform CRA_b {ECO:0000313|EMBL:EAW88252.1}; SubName: Full=Testicular tissue protein Li 143 {ECO:0000313|EMBL:AEE61054.1};+++[A0A024R8I7_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q8WUW2_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q96IS9_HUMAN|Unreviewed]SubName: Full=AGPAT2 protein {ECO:0000313|EMBL:AAH07269.1}; Flags: Fragment;"]
[10556,"'RPP30'",169,154,146,156.333333333333,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex+++GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004540///ribonuclease activity+++GO:0004526///ribonuclease P activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity","GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","ribonuclease P/MRP subunit p30","[RPP30_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p30; Short=RNaseP protein p30; EC=3.1.26.5; AltName: Full=RNase P subunit 2;+++[Q5VU10_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000407972}; Flags: Fragment;+++[Q5VU11_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000277882}; Flags: Fragment;"]
[10557,"'RPP38'",202,209,185,198.666666666667,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090501///RNA phosphodiester bond hydrolysis","ribonuclease P/MRP subunit p38","[RPP38_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p38; Short=RNaseP protein p38; EC=3.1.26.5;+++[Q5VUC3_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000402635}; Flags: Fragment;+++[Q5VUC9_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000367443};"]
[10558,"'SPTLC1'",710,584,681,658.333333333333,"00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway+++01100///Metabolic pathways+++04138///Autophagy - yeast","H00265///Hereditary sensory and autonomic neuropathy (HSAN)","M00099///Sphingosine biosynthesis+++M00094///Ceramide biosynthesis","R01281///Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)   Palmitoyl-CoA + L-Serine <=> 3-Dehydrosphinganine + CoA + CO2","GO:0017059///serine C-palmitoyltransferase complex+++GO:0016020///membrane+++GO:0035339///SPOTS complex+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0030170///pyridoxal phosphate binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0004758///serine C-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0030148///sphingolipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0046511///sphinganine biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0046513///ceramide biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046512///sphingosine biosynthetic process+++GO:1904504///positive regulation of lipophagy","serine palmitoyltransferase long chain base subunit 1","[SPTC1_HUMAN|Reviewed]RecName: Full=Serine palmitoyltransferase 1; EC=2.3.1.50; AltName: Full=Long chain base biosynthesis protein 1; Short=LCB 1; AltName: Full=Serine-palmitoyl-CoA transferase 1; Short=SPT 1; Short=SPT1;+++[A0A024R277_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase, long chain base subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW62805.1};+++[A0A2R8Y4S0_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000493933};+++[A0A2R8Y6A2_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495388};+++[A0A2R8Y763_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495764}; Flags: Fragment;+++[L8E7V1_HUMAN|Unreviewed]SubName: Full=Alternative protein SPTLC1 {ECO:0000313|EMBL:CCQ43355.1};+++[Q6NUL7_HUMAN|Unreviewed]SubName: Full=SPTLC1 protein {ECO:0000313|EMBL:AAH68537.1};"]
[10559,"'SLC35A1'",72,65,70,69,"04137///Mitophagy - animal+++00970///Aminoacyl-tRNA biosynthesis+++04140///Autophagy - animal","H01392///Arthrogryposis, mental retardation, and seizures (AMRS)+++H00606///Early infantile epileptic encephalopathy+++H00119///Congenital disorders of glycosylation (CDG) type II","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03646///L-Arginine:tRNA(Arg) ligase (AMP-forming) ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)","GO:0005794///Golgi apparatus+++GO:0030173///integral component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0015136///sialic acid transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity+++GO:0005456///CMP-N-acetylneuraminate transmembrane transporter activity","GO:0015782///CMP-N-acetylneuraminate transmembrane transport+++GO:0008643///carbohydrate transport+++GO:0015739///sialic acid transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport+++GO:0006464///cellular protein modification process+++GO:0005975///carbohydrate metabolic process","solute carrier family 35 member A1","[S35A1_HUMAN|Reviewed]RecName: Full=CMP-sialic acid transporter; Short=CMP-SA-Tr; Short=CMP-Sia-Tr; AltName: Full=Solute carrier family 35 member A1;+++[A0A087WVM1_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|Ensembl:ENSP00000479535};+++[Q5W1L6_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65470.1};+++[Q5W1L7_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65469.1, ECO:0000313|Ensembl:ENSP00000358570};+++[Q6A0F2_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17781.1};+++[Q6A0F3_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17780.1};"]
[1056,"'CEL'",146,173,134,151,"04975///Fat digestion and absorption+++01100///Metabolic pathways+++00561///Glycerolipid metabolism+++00100///Steroid biosynthesis+++04972///Pancreatic secretion","H00410///Maturity onset diabetes of the young (MODY)","M00098///Acylglycerol degradation","R01462///cholesterol ester acylhydrolase   Cholesterol ester + H2O <=> Cholesterol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase   1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid+++R02250///triacylglycerol acylhydrolase   Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid","GO:0009986///cell surface+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0098793///presynapse+++GO:0005737///cytoplasm","GO:0004806///triglyceride lipase activity+++GO:0042043///neurexin family protein binding+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003824///catalytic activity+++GO:0038023///signaling receptor activity+++GO:0004771///sterol esterase activity+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016787///hydrolase activity","GO:0006629///lipid metabolic process+++GO:0044258///intestinal lipid catabolic process+++GO:0007158///neuron cell-cell adhesion+++GO:0016042///lipid catabolic process+++GO:0044241///lipid digestion+++GO:0006707///cholesterol catabolic process+++GO:0097104///postsynaptic membrane assembly+++GO:0050804///modulation of chemical synaptic transmission+++GO:0018350///protein esterification+++GO:0030299///intestinal cholesterol absorption+++GO:0097105///presynaptic membrane assembly+++GO:0009062///fatty acid catabolic process+++GO:0046514///ceramide catabolic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0030157///pancreatic juice secretion","carboxyl ester lipase","[CEL_HUMAN|Reviewed]RecName: Full=Bile salt-activated lipase; Short=BAL; EC=3.1.1.13; EC=3.1.1.3; AltName: Full=Bile salt-stimulated lipase; Short=BSSL; AltName: Full=Bucelipase; AltName: Full=Carboxyl ester lipase; AltName: Full=Cholesterol esterase; AltName: Full=Pancreatic lysophospholipase; AltName: Full=Sterol esterase; Flags: Precursor;+++[B4DSX9_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};+++[O75612_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[Q86SR3_HUMAN|Unreviewed]SubName: Full=CEL protein {ECO:0000313|EMBL:AAH42510.1};+++[X6R868_HUMAN|Unreviewed]SubName: Full=Bile salt-activated lipase {ECO:0000313|Ensembl:ENSP00000361151};"]
[10560,"'SLC19A2'",145,130,154,143,"04977///Vitamin digestion and absorption","H01231///Biotin-responsive basal ganglia disease (BBGD)+++H01183///Thiamine-responsive megaloblastic anemia (TRMA)+++H01565///Wernicke encephalopathy",null,null,"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0015234///thiamine transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity","GO:0042723///thiamine-containing compound metabolic process+++GO:0071934///thiamine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0015888///thiamine transport+++GO:0035461///vitamin transmembrane transport+++GO:0015884///folic acid transport+++GO:0051180///vitamin transport","solute carrier family 19 member 2","[S19A2_HUMAN|Reviewed]RecName: Full=Thiamine transporter 1; Short=ThTr-1; Short=ThTr1; AltName: Full=Solute carrier family 19 member 2; AltName: Full=Thiamine carrier 1; Short=TC1;+++[A0A024R8Y5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_c {ECO:0000313|EMBL:EAW90847.1}; SubName: Full=Solute carrier family 19 member 2 isoform 1 {ECO:0000313|EMBL:ALQ33992.1};+++[A0A024R928_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_a {ECO:0000313|EMBL:EAW90845.1}; SubName: Full=Solute carrier family 19 member 2 isoform 2 {ECO:0000313|EMBL:ALQ33993.1};+++[A0A2R8Y5B5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_b {ECO:0000313|EMBL:EAW90844.1}; SubName: Full=Thiamine transporter 1 {ECO:0000313|Ensembl:ENSP00000494404};+++[B0FBR7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 thiamine transporter member 2 {ECO:0000313|EMBL:ABY51619.1}; Flags: Fragment;+++[E3UTN9_HUMAN|Unreviewed]SubName: Full=SLC19A2 solute carrier family 19 member 2 {ECO:0000313|EMBL:ADP24156.1}; Flags: Fragment;+++[I7BB09_HUMAN|Unreviewed]SubName: Full=Thiamnine trasporter protein {ECO:0000313|EMBL:AFO38177.2}; Flags: Fragment;+++[Q7Z7J1_HUMAN|Unreviewed]SubName: Full=Thiamine transporter THTR-1 {ECO:0000313|EMBL:AAP37965.1}; Flags: Fragment;"]
[10561,"'IFI44'",54,12,12,26,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005525///GTP binding","GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0009615///response to virus","interferon induced protein 44","[IFI44_HUMAN|Reviewed]RecName: Full=Interferon-induced protein 44; Short=p44; AltName: Full=Microtubule-associated protein 44;+++[C9JUM8_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000399477}; Flags: Fragment;+++[H7C1F3_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000400001}; Flags: Fragment;"]
[10564,"'ARFGEF2'",668,391,565,541.333333333333,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0005829///cytosol+++GO:0005879///axonemal microtubule+++GO:0032279///asymmetric synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0043197///dendritic spine+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0030054///cell junction+++GO:0032280///symmetric synapse+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0005856///cytoskeleton+++GO:0055037///recycling endosome+++GO:0030425///dendrite+++GO:0005815///microtubule organizing center+++GO:0005768///endosome+++GO:0042995///cell projection","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0050811///GABA receptor binding","GO:0032012///regulation of ARF protein signal transduction+++GO:0006887///exocytosis+++GO:0001881///receptor recycling+++GO:0006893///Golgi to plasma membrane transport+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0007032///endosome organization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction","ADP ribosylation factor guanine nucleotide exchange factor 2","[BIG2_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Short=Brefeldin A-inhibited GEP 2; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2;+++[L8E9E5_HUMAN|Unreviewed]SubName: Full=Alternative protein ARFGEF2 {ECO:0000313|EMBL:CCQ43356.1};+++[Q59FR3_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2 variant {ECO:0000313|EMBL:BAD92634.1}; Flags: Fragment;+++[Q86TH5_HUMAN|Unreviewed]SubName: Full=ARFGEF2 protein {ECO:0000313|EMBL:AAH50449.1}; Flags: Fragment;"]
[10565,"'ARFGEF1'",1077,622,754,817.666666666667,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0000139///Golgi membrane+++GO:0016363///nuclear matrix+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005096///GTPase activator activity+++GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0051897///positive regulation of protein kinase B signaling+++GO:0090284///positive regulation of protein glycosylation in Golgi+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0034260///negative regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0090303///positive regulation of wound healing+++GO:0030837///negative regulation of actin filament polymerization+++GO:0006887///exocytosis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0031175///neuron projection development","ADP ribosylation factor guanine nucleotide exchange factor 1","[BIG1_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Short=Brefeldin A-inhibited GEP 1; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1; AltName: Full=p200 ARF guanine nucleotide exchange factor; AltName: Full=p200 ARF-GEP1;+++[A0A024R7X0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1(Brefeldin A-inhibited), isoform CRA_a {ECO:0000313|EMBL:EAW86936.1};+++[E5RHL7_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000430891}; Flags: Fragment;+++[E5RHZ1_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429560}; Flags: Fragment;+++[E5RIF2_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000428429}; Flags: Fragment;+++[E5RJN9_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429002}; Flags: Fragment;"]
[10566,"'AKAP3'",17,9,18,14.6666666666667,{"$nulls":4},"GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0097228///sperm principal piece","GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0007340///acrosome reaction+++GO:0008104///protein localization+++GO:0007338///single fertilization+++GO:0001835///blastocyst hatching+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway","A-kinase anchoring protein 3","[AKAP3_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 3; Short=AKAP-3; AltName: Full=A-kinase anchor protein 110 kDa; Short=AKAP 110; AltName: Full=Cancer/testis antigen 82; Short=CT82; AltName: Full=Fibrous sheath protein of 95 kDa; Short=FSP95; AltName: Full=Fibrousheathin I; AltName: Full=Fibrousheathin-1; AltName: Full=Protein kinase A-anchoring protein 3; Short=PRKA3; AltName: Full=Sperm oocyte-binding protein;+++[F5H2S4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000439382}; Flags: Fragment;+++[F5H7P4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000442376}; Flags: Fragment;+++[V9HWD4_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 159 {ECO:0000313|EMBL:ACJ13735.1};"]
[10567,"'RABAC1'",2167,2697,2103,2322.33333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0005794///Golgi apparatus+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0070064///proline-rich region binding",null,"Rab acceptor 1","[PRAF1_HUMAN|Reviewed]RecName: Full=Prenylated Rab acceptor protein 1; AltName: Full=PRA1 family protein 1;+++[M0QXH1_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0QXU8_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[M0R1H9_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0R3D4_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10568,"'SLC34A2'",3,1,2,2,"04928///Parathyroid hormone synthesis, secretion and action","H00888///Nephrolithiasis/osteoporosis, hypophosphatemic+++H02138///Hereditary hypophophatemic rickets with hypercalciuria+++H01198///Fanconi renotubular syndrome (FTS)+++H00214///Hypophosphatemic rickets+++H01298///Pulmonary alveolar microlithiasis (PALM)",null,null,"GO:0031982///vesicle+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0016020///membrane+++GO:0005903///brush border","GO:0042301///phosphate ion binding+++GO:0015321///sodium-dependent phosphate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0005436///sodium:phosphate symporter activity+++GO:0031402///sodium ion binding","GO:0006817///phosphate ion transport+++GO:0001701///in utero embryonic development+++GO:0055085///transmembrane transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0006811///ion transport+++GO:0044267///cellular protein metabolic process+++GO:0043627///response to estrogen+++GO:0044341///sodium-dependent phosphate transport+++GO:0035725///sodium ion transmembrane transport+++GO:0006814///sodium ion transport","solute carrier family 34 member 2","[NPT2B_HUMAN|Reviewed]RecName: Full=Sodium-dependent phosphate transport protein 2B; Short=Sodium-phosphate transport protein 2B; AltName: Full=Na(+)-dependent phosphate cotransporter 2B; AltName: Full=NaPi3b; AltName: Full=Sodium/phosphate cotransporter 2B; Short=Na(+)/Pi cotransporter 2B; Short=NaPi-2b; AltName: Full=Solute carrier family 34 member 2;+++[A0A0B5E3E9_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|EMBL:AJE59606.1}; Flags: Fragment;+++[D6RA94_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|Ensembl:ENSP00000423038}; Flags: Fragment;+++[D6RBC0_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|Ensembl:ENSP00000424266}; Flags: Fragment;"]
[10569,"'SLU7'",576,586,540,567.333333333333,"03040///Spliceosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0030628///pre-mRNA 3'-splice site binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0000386///second spliceosomal transesterification activity","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006406///mRNA export from nucleus+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000389///mRNA 3'-splice site recognition+++GO:0034605///cellular response to heat+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0006886///intracellular protein transport","SLU7 homolog, splicing factor","[SLU7_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SLU7; Short=hSlu7;+++[A0A0C4DGD2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428362}; Flags: Fragment;+++[E5RGM7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000429990}; Flags: Fragment;+++[E5RK41_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428943}; Flags: Fragment;"]
[10570,"'DPYSL4'",1191,1255,1087,1177.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0031005///filamin binding","GO:0097485///neuron projection guidance+++GO:0070997///neuron death+++GO:0007399///nervous system development","dihydropyrimidinase like 4","[DPYL4_HUMAN|Reviewed]RecName: Full=Dihydropyrimidinase-related protein 4; Short=DRP-4; AltName: Full=Collapsin response mediator protein 3; Short=CRMP-3; AltName: Full=UNC33-like phosphoprotein 4; Short=ULIP-4;+++[D3DRG7_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-like 4, isoform CRA_a {ECO:0000313|EMBL:EAW49133.1};+++[Q5T0Q6_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-related protein 4 {ECO:0000313|Ensembl:ENSP00000357616};"]
[10572,"'SIVA1'",173,212,228,204.333333333333,"04115///p53 signaling pathway",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0001618///virus receptor activity+++GO:0046872///metal ion binding+++GO:0005175///CD27 receptor binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0008270///zinc ion binding","GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006915///apoptotic process+++GO:0046718///viral entry into host cell+++GO:0006924///activation-induced cell death of T cells+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0016032///viral process+++GO:0097191///extrinsic apoptotic signaling pathway","SIVA1 apoptosis inducing factor","[SIVA_HUMAN|Reviewed]RecName: Full=Apoptosis regulatory protein Siva; AltName: Full=CD27-binding protein; Short=CD27BP;+++[B4DTY2_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79449, highly similar to Apoptosis regulatory protein Siva {ECO:0000313|EMBL:BAG65628.1};+++[G3V3U1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451427};+++[G3V439_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451570}; Flags: Fragment;+++[H0YJN1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451823};"]
[10573,"'MRPL28'",1073,1152,1010,1078.33333333333,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005761///mitochondrial ribosome+++GO:0005739///mitochondrion","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","mitochondrial ribosomal protein L28","[RM28_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L28, mitochondrial; Short=L28mt; Short=MRP-L28; AltName: Full=Melanoma antigen p15; AltName: Full=Melanoma-associated antigen recognized by T-lymphocytes; AltName: Full=Mitochondrial large ribosomal subunit protein bL28m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[P13986_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:CAA34647.1};+++[Q9NRK2_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAF76751.1};+++[Q9UM95_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAD14186.1}; Flags: Fragment;"]
[10574,"'CCT7'",2470,2337,2203,2336.66666666667,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0005874///microtubule+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0050821///protein stabilization+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0006457///protein folding","chaperonin containing TCP1 subunit 7","[TCPH_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit eta; Short=TCP-1-eta; AltName: Full=CCT-eta; AltName: Full=HIV-1 Nef-interacting protein; Contains: RecName: Full=T-complex protein 1 subunit eta, N-terminally processed;+++[A0A0D9SG95_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[B7Z1C9_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[F8WAM2_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042}; Flags: Fragment;+++[F8WBP8_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[Q6IBT3_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};"]
[10575,"'CCT4'",1719,1410,1442,1523.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005832///chaperonin-containing T-complex+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0002199///zona pellucida receptor complex+++GO:0042470///melanosome+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0005874///microtubule","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0051082///unfolded protein binding","GO:1904871///positive regulation of protein localization to Cajal body+++GO:0090666///scaRNA localization to Cajal body+++GO:0006457///protein folding+++GO:0050821///protein stabilization+++GO:0051973///positive regulation of telomerase activity+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida","chaperonin containing TCP1 subunit 4","[TCPD_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit delta; Short=TCP-1-delta; AltName: Full=CCT-delta; AltName: Full=Stimulator of TAR RNA-binding;"]
[10576,"'CCT2'",1210,1297,1166,1224.33333333333,{"$nulls":4},"GO:0044297///cell body+++GO:0043209///myelin sheath+++GO:0005874///microtubule+++GO:0002199///zona pellucida receptor complex+++GO:0005829///cytosol+++GO:0035578///azurophil granule lumen+++GO:0005832///chaperonin-containing T-complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005524///ATP binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0050821///protein stabilization+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:0051086///chaperone mediated protein folding independent of cofactor+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0090666///scaRNA localization to Cajal body+++GO:0007339///binding of sperm to zona pellucida+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0043312///neutrophil degranulation+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0006457///protein folding","chaperonin containing TCP1 subunit 2","[TCPB_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;+++[F5GWF6_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000441847};+++[F8VQ14_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000450153};+++[V9HW96_HUMAN|Unreviewed]SubName: Full=Chaperonin containing TCP1, subunit 2 (Beta), isoform CRA_b {ECO:0000313|EMBL:EAW97229.1}; SubName: Full=Epididymis secretory sperm binding protein Li 100n {ECO:0000313|EMBL:ACI46043.1};"]
[10577,"'NPC2'",10073,11189,11091,10784.3333333333,"04142///Lysosome+++04979///Cholesterol metabolism","H00136///Niemann-Pick disease type C (NPC)",null,null,"GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035578///azurophil granule lumen+++GO:0043202///lysosomal lumen+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005623///cell","GO:0019899///enzyme binding+++GO:0017127///cholesterol transporter activity+++GO:0015485///cholesterol binding+++GO:0005515///protein binding","GO:0030301///cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0046836///glycolipid transport+++GO:0015914///phospholipid transport+++GO:0032366///intracellular sterol transport+++GO:0008202///steroid metabolic process+++GO:0043312///neutrophil degranulation+++GO:0042632///cholesterol homeostasis+++GO:0006869///lipid transport+++GO:0034383///low-density lipoprotein particle clearance+++GO:0019747///regulation of isoprenoid metabolic process+++GO:0006629///lipid metabolic process+++GO:0009615///response to virus+++GO:0032367///intracellular cholesterol transport+++GO:0008203///cholesterol metabolic process","NPC intracellular cholesterol transporter 2","[NPC2_HUMAN|Reviewed]RecName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000312|HGNC:HGNC:14537}; AltName: Full=Epididymal secretory protein E1; AltName: Full=Human epididymis-specific protein 1; Short=He1 {ECO:0000303|PubMed:11125141, ECO:0000303|PubMed:8418812}; AltName: Full=Niemann-Pick disease type C2 protein {ECO:0000303|PubMed:17018531}; Flags: Precursor;+++[A0A024R6C0_HUMAN|Unreviewed]SubName: Full=Niemann-Pick disease, type C2, isoform CRA_a {ECO:0000313|EMBL:EAW81177.1};+++[E7EMS2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000412103};+++[G3V2V8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450887}; Flags: Fragment;+++[G3V3D1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451180}; Flags: Fragment;+++[G3V3E8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451206};+++[H0YIZ1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450502}; Flags: Fragment;+++[H0YJE2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451314}; Flags: Fragment;+++[J3KMY5_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000238633};"]
[10579,"'TACC2'",454,415,396,421.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0035257///nuclear hormone receptor binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization","transforming acidic coiled-coil containing protein 2","[TACC2_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 2; AltName: Full=Anti-Zuai-1; Short=AZU-1;+++[A0A0U1RRM9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489610}; Flags: Fragment;+++[B2RWP4_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI50628.1};+++[B7ZMJ9_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI44600.1};+++[D6RAA5_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422815};+++[E7EMZ9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000427618};+++[E9PBC6_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424467};+++[E9PGB3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000420967}; Flags: Fragment;+++[H0Y8P9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000421702}; Flags: Fragment;+++[H0Y911_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422725}; Flags: Fragment;+++[H0Y954_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423069}; Flags: Fragment;+++[H0Y9C3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423764}; Flags: Fragment;+++[H0Y9Y7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425525}; Flags: Fragment;+++[H0YA73_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000426303}; Flags: Fragment;+++[Q4VXL4_HUMAN|Unreviewed]SubName: Full=HCG41426, isoform CRA_c {ECO:0000313|EMBL:EAW49324.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357997};+++[Q4VXL8_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357995};"]
[1058,"'CENPA'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000786///nucleosome+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0000775///chromosome, centromeric region+++GO:0000939///condensed chromosome inner kinetochore+++GO:0000788///nuclear nucleosome+++GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0031618///nuclear pericentric heterochromatin","GO:0003682///chromatin binding+++GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0016032///viral process+++GO:0000132///establishment of mitotic spindle orientation+++GO:0006334///nucleosome assembly+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0051382///kinetochore assembly+++GO:0000281///mitotic cytokinesis","centromere protein A","[CENPA_HUMAN|Reviewed]RecName: Full=Histone H3-like centromeric protein A; AltName: Full=Centromere autoantigen A; AltName: Full=Centromere protein A; Short=CENP-A;+++[F8WD88_HUMAN|Unreviewed]SubName: Full=Histone H3-like centromeric protein A {ECO:0000313|Ensembl:ENSP00000404963};"]
[10580,"'SORBS1'",216,160,206,194,"03320///PPAR signaling pathway+++04910///Insulin signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005899///insulin receptor complex+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0045121///membrane raft+++GO:0005924///cell-substrate adherens junction+++GO:0005813///centrosome+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0005915///zonula adherens+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix+++GO:0005913///cell-cell adherens junction","GO:0005515///protein binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005158///insulin receptor binding+++GO:0008092///cytoskeletal protein binding+++GO:0003779///actin binding","GO:0048041///focal adhesion assembly+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046326///positive regulation of glucose import+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0043149///stress fiber assembly+++GO:0032869///cellular response to insulin stimulus+++GO:0006936///muscle contraction+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007160///cell-matrix adhesion+++GO:0007015///actin filament organization","sorbin and SH3 domain containing 1","[SRBS1_HUMAN|Reviewed]RecName: Full=Sorbin and SH3 domain-containing protein 1; AltName: Full=Ponsin; AltName: Full=SH3 domain protein 5; AltName: Full=SH3P12; AltName: Full=c-Cbl-associated protein; Short=CAP;+++[A0A0U1RQI5_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000489022}; Flags: Fragment;+++[B4DTX5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60072, highly similar to Homo sapiens sorbin and SH3 domain containing 1 (SORBS1), transcript variant 6, mRNA {ECO:0000313|EMBL:BAG62137.1};+++[D3DR43_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain containing 1, isoform CRA_e {ECO:0000313|EMBL:EAW50004.1};+++[Q5T925_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000360272}; Flags: Fragment;+++[S4R303_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000473813}; Flags: Fragment;+++[S4R406_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000474932}; Flags: Fragment;"]
[10581,"'IFITM2'",727,889,790,802,"04662///B cell receptor signaling pathway","H00506///Osteogenesis imperfecta",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0005886///plasma membrane",null,"GO:0035456///response to interferon-beta+++GO:0035455///response to interferon-alpha+++GO:0051607///defense response to virus+++GO:0009615///response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0006955///immune response+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0034341///response to interferon-gamma+++GO:0046597///negative regulation of viral entry into host cell+++GO:0002376///immune system process","interferon induced transmembrane protein 2","[IFM2_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 2; AltName: Full=Dispanin subfamily A member 2c; Short=DSPA2c; AltName: Full=Interferon-inducible protein 1-8D;+++[E9PQN9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000434443};+++[H0YCL2_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000431850}; Flags: Fragment;+++[H7BYV1_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000382712}; Flags: Fragment;+++[Q6IBB0_HUMAN|Unreviewed]SubName: Full=IFITM2 protein {ECO:0000313|EMBL:CAG33175.1}; SubName: Full=Interferon induced transmembrane protein 2 (1-8D) {ECO:0000313|EMBL:AAP88861.1};"]
[10584,"'COLEC10'",0,2,1,1,"04380///Osteoclast differentiation+++04060///Cytokine-cytokine receptor interaction","H01887///3MC syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0048029///monosaccharide binding+++GO:0004252///serine-type endopeptidase activity+++GO:0005537///mannose binding+++GO:0042056///chemoattractant activity+++GO:0030246///carbohydrate binding","GO:0006956///complement activation+++GO:0050918///positive chemotaxis+++GO:1904888///cranial skeletal system development+++GO:0001867///complement activation, lectin pathway+++GO:0006508///proteolysis","collectin subfamily member 10","[COL10_HUMAN|Reviewed]RecName: Full=Collectin-10; AltName: Full=Collectin liver protein 1; Short=CL-L1; AltName: Full=Collectin-34; Short=CL-34; Flags: Precursor;+++[A0A024R9J3_HUMAN|Unreviewed]SubName: Full=Collectin sub-family member 10 (C-type lectin), isoform CRA_a {ECO:0000313|EMBL:EAW91980.1};"]
[10585,"'POMT1'",985,980,1000,988.333333333333,"00515///Mannose type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++01100///Metabolic pathways","H01960///Muscular dystrophy-dystroglycanopathy type B+++H00593///Limb-girdle muscular dystrophy (LGMD)+++H00120///Muscular dystrophy-dystroglycanopathy type A+++H01959///Muscular dystrophy-dystroglycanopathy type C+++H00590///Congenital muscular dystrophies (CMD/MDC)",null,"R07620///Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027+++R04072///dolichyl-beta-D-mannosyl-phosphate:protein-serine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]+++R11399///dolichyl-beta-D-mannosyl-phosphate:protein-threonine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein]","GO:0016021///integral component of membrane+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0097502///mannosylation+++GO:0030198///extracellular matrix organization+++GO:0035269///protein O-linked mannosylation+++GO:0007275///multicellular organism development+++GO:0006486///protein glycosylation+++GO:1904100///positive regulation of protein O-linked glycosylation+++GO:0005975///carbohydrate metabolic process+++GO:0006493///protein O-linked glycosylation","protein O-mannosyltransferase 1","[POMT1_HUMAN|Reviewed]RecName: Full=Protein O-mannosyl-transferase 1; EC=2.4.1.109; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 1;+++[A0A140VKE0_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 57p {ECO:0000313|EMBL:AEE61277.1};+++[A0A1L6C7Q4_HUMAN|Unreviewed]SubName: Full=Truncated O-mannosyl-transferase 1 variant SV3DEL {ECO:0000313|EMBL:APQ46216.1}; EC=2.4.1.109 {ECO:0000313|EMBL:APQ46216.1};+++[A0A1V1FTP4_HUMAN|Unreviewed]SubName: Full=POMT1 protein {ECO:0000313|EMBL:BAX07485.1};+++[Q5JSZ6_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000390737}; Flags: Fragment;+++[Q5JT02_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000361294}; Flags: Fragment;+++[Q5JT03_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000395060}; Flags: Fragment;+++[Q5JT04_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000405149}; Flags: Fragment;+++[Q5JT05_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000402083}; Flags: Fragment;+++[Q5JT07_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000403736}; Flags: Fragment;"]
[10586,"'MAB21L2'",1063,1091,1153,1102.33333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0043010///camera-type eye development+++GO:0010172///embryonic body morphogenesis+++GO:0007399///nervous system development+++GO:0001654///eye development+++GO:0008284///positive regulation of cell proliferation","mab-21 like 2","[MB212_HUMAN|Reviewed]RecName: Full=Protein mab-21-like 2;"]
[10587,"'TXNRD2'",347,392,352,363.666666666667,"05225///Hepatocellular carcinoma+++05200///Pathways in cancer+++00450///Selenocompound metabolism","H00256///Familial glucocorticoid deficiency (FGD)",null,"R09372///methaneselenol:NADP+ oxidoreductase   2 NADPH + 2 H+ + Methylselenic acid <=> 2 NADP+ + 2 H2O + Methaneselenol+++R03596///hydrogen selenide:NADP+ oxidoreductase   Hydrogen selenide + 3 NADP+ + 3 H2O <=> Selenite + 3 NADPH + 5 H+","GO:0005623///cell+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0050660///flavin adenine dinucleotide binding+++GO:0004791///thioredoxin-disulfide reductase activity+++GO:0009055///electron transfer activity","GO:0034599///cellular response to oxidative stress+++GO:0022900///electron transport chain+++GO:0055114///oxidation-reduction process+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification+++GO:0000305///response to oxygen radical","thioredoxin reductase 2","[TRXR2_HUMAN|Reviewed]RecName: Full=Thioredoxin reductase 2, mitochondrial; EC=1.8.1.9; AltName: Full=Selenoprotein Z; Short=SelZ; AltName: Full=TR-beta; AltName: Full=Thioredoxin reductase TR3; Flags: Precursor;+++[A0A096LNY7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485290}; Flags: Fragment;+++[A0A096LP96_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485466};+++[A0A096LPB7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485499};+++[A0A096LPD9_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485543};+++[A0A096LPH4_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485603};+++[A0A096LPK7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485665};+++[A0A0U1RQX0_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000489208}; Flags: Fragment;+++[A0A182DWF2_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383362};+++[A0A182DWF3_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383363};+++[A4FTY4_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAH99923.1};+++[D3YTF8_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383369};+++[E7EWK1_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000334451};+++[Q17RE6_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAI17355.1};"]
[10588,"'MTHFS'",79,99,85,87.6666666666667,"00670///One carbon pool by folate+++01100///Metabolic pathways",null,null,"R02301///5-Formyltetrahydrofolate cyclo-ligase (ADP-forming)   ATP + Folinic acid + H+ <=> ADP + Orthophosphate + 5,10-Methenyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix","GO:0005542///folic acid binding+++GO:0005524///ATP binding+++GO:0030272///5-formyltetrahydrofolate cyclo-ligase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016874///ligase activity","GO:0006536///glutamate metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0015942///formate metabolic process+++GO:0046655///folic acid metabolic process+++GO:0046657///folic acid catabolic process+++GO:0009396///folic acid-containing compound biosynthetic process+++GO:0035999///tetrahydrofolate interconversion","methenyltetrahydrofolate synthetase","[MTHFS_HUMAN|Reviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase; EC=6.3.3.2; AltName: Full=5,10-methenyl-tetrahydrofolate synthetase; Short=MTHFS; Short=Methenyl-THF synthetase;+++[A0A0U1RQM3_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279};+++[H3BMB9_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454318}; Flags: Fragment;+++[H3BN04_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454626};+++[Q96EE9_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279}; Flags: Fragment;"]
[10589,"'DRAP1'",634,710,592,645.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","DR1 associated protein 1","[NC2A_HUMAN|Reviewed]RecName: Full=Dr1-associated corepressor; AltName: Full=Dr1-associated protein 1; AltName: Full=Negative cofactor 2-alpha; Short=NC2-alpha;+++[C9JCC6_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000366190};+++[E9PMW2_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437287};+++[E9PNC7_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437225}; Flags: Fragment;+++[E9PQX9_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000432445};"]
[1059,"'CENPB'",1851,2069,1894,1938,{"$nulls":4},"GO:0016604///nuclear body+++GO:0031618///nuclear pericentric heterochromatin+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0005634///nucleus","GO:0003696///satellite DNA binding+++GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0019237///centromeric DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding",null,"centromere protein B","[CENPB_HUMAN|Reviewed]RecName: Full=Major centromere autoantigen B; AltName: Full=Centromere protein B; Short=CENP-B;"]
[10590,"'SCGN'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0030658///transport vesicle membrane+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0098793///presynapse","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0008150///biological_process+++GO:1900271///regulation of long-term synaptic potentiation+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0051480///regulation of cytosolic calcium ion concentration","secretagogin, EF-hand calcium binding protein","[SEGN_HUMAN|Reviewed]RecName: Full=Secretagogin;+++[Q96P10_HUMAN|Unreviewed]SubName: Full=Secretagogin, EF-hand calcium binding protein, isoform CRA_b {ECO:0000313|EMBL:EAW55488.1}; SubName: Full=Setagin {ECO:0000313|EMBL:AAL16052.1};"]
[10591,"'DNPH1'",342,431,380,384.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0070694///deoxyribonucleoside 5'-monophosphate N-glycosidase activity+++GO:0042803///protein homodimerization activity+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0016798///hydrolase activity, acting on glycosyl bonds","GO:0008152///metabolic process+++GO:0009159///deoxyribonucleoside monophosphate catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0009116///nucleoside metabolic process+++GO:0006195///purine nucleotide catabolic process+++GO:0008283///cell proliferation+++GO:0009117///nucleotide metabolic process+++GO:0030307///positive regulation of cell growth","2'-deoxynucleoside 5'-phosphate N-hydrolase 1","[DNPH1_HUMAN|Reviewed]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036, ECO:0000269|PubMed:24260472, ECO:0000269|PubMed:25108359}; AltName: Full=c-Myc-responsive protein RCL {ECO:0000255|HAMAP-Rule:MF_03036};+++[H0Y8X4_HUMAN|Unreviewed]SubName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000313|Ensembl:ENSP00000422440}; Flags: Fragment;"]
[10592,"'SMC2'",264,189,181,211.333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0070062///extracellular exosome+++GO:0005730///nucleolus+++GO:0000228///nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0046982///protein heterodimerization activity","GO:0051301///cell division+++GO:0045132///meiotic chromosome segregation+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0051383///kinetochore organization","structural maintenance of chromosomes 2","[SMC2_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 2; Short=SMC protein 2; Short=SMC-2; AltName: Full=Chromosome-associated protein E; Short=hCAP-E; AltName: Full=XCAP-E homolog;+++[A0A024R158_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[A8K984_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B3KMB1_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B7ZLZ7_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[Q05BV1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH32705.1}; Flags: Fragment;+++[Q05D74_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH17845.1}; Flags: Fragment;+++[Q6IPS5_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH71750.1}; Flags: Fragment;+++[Q7Z2X1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH55081.1}; Flags: Fragment;"]
[10594,"'PRPF8'",6891,6282,6703,6625.33333333333,"03040///Spliceosome","H00527///Retinitis pigmentosa (RP)","M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005682///U5 snRNP+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0016020///membrane","GO:0000386///second spliceosomal transesterification activity+++GO:0097157///pre-mRNA intronic binding+++GO:0030623///U5 snRNA binding+++GO:0003723///RNA binding+++GO:0030620///U2 snRNA binding+++GO:0017070///U6 snRNA binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0030619///U1 snRNA binding+++GO:0005515///protein binding","GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0006397///mRNA processing+++GO:0071356///cellular response to tumor necrosis factor+++GO:0008380///RNA splicing","pre-mRNA processing factor 8","[PRP8_HUMAN|Reviewed]RecName: Full=Pre-mRNA-processing-splicing factor 8; AltName: Full=220 kDa U5 snRNP-specific protein; AltName: Full=PRP8 homolog; AltName: Full=Splicing factor Prp8; AltName: Full=p220;+++[I3L0J9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000458151}; Flags: Fragment;+++[I3L1T8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000459095}; Flags: Fragment;+++[I3L3Z8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000460849}; Flags: Fragment;"]
[10595,"'ERN2'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990604///IRE1-TRAF2-ASK1 complex","GO:0000166///nucleotide binding+++GO:0004540///ribonuclease activity+++GO:0004519///endonuclease activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0000287///magnesium ion binding","GO:0006397///mRNA processing+++GO:0007050///cell cycle arrest+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008152///metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0030263///apoptotic chromosome condensation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0007257///activation of JUN kinase activity+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0016075///rRNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis","endoplasmic reticulum to nucleus signaling 2","[ERN2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2; AltName: Full=Endoplasmic reticulum-to-nucleus signaling 2; AltName: Full=Inositol-requiring protein 2; Short=hIRE2p; AltName: Full=Ire1-beta; Short=IRE1b; Includes: RecName: Full=Serine/threonine-protein kinase; EC=2.7.11.1; Includes: RecName: Full=Endoribonuclease; EC=3.1.26.-; Flags: Precursor;+++[A5YM46_HUMAN|Unreviewed]SubName: Full=ERN2 protein {ECO:0000313|EMBL:ABQ59030.1};+++[A5YM65_HUMAN|Unreviewed]SubName: Full=ERN2 protein {ECO:0000313|EMBL:ABQ59049.1};+++[E7ETG2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000413812};+++[H3BSU1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000456866}; Flags: Fragment;+++[H3BTW8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000457361};+++[H3BUU2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000457796};"]
[10597,"'TRAPPC2B'",21.74,21,34.68,25.8066666666667,null,"H00760///Spondyloepiphyseal dysplasia tarda",null,null,"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0008134///transcription factor binding+++GO:0044325///ion channel binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport","trafficking protein particle complex 2B","[TPC2A_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2; AltName: Full=Sedlin;+++[TPC2B_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2B; AltName: Full=MBP-1-interacting protein 2A; Short=MIP-2A;+++[TPPC2_BOVIN|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_CANLF|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_PONAB|diamond]RecName: Full=Trafficking protein particle complex subunit 2;"]
[10598,"'AHSA1'",930,960,855,915,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0001671///ATPase activator activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0032781///positive regulation of ATPase activity","activator of HSP90 ATPase activity 1","[AHSA1_HUMAN|Reviewed]RecName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1; Short=AHA1; AltName: Full=p38;+++[G3V3W9_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451467};+++[G3V438_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451569}; Flags: Fragment;+++[H0YJ63_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000450890}; Flags: Fragment;+++[H0YJG7_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451475}; Flags: Fragment;+++[H0YJU2_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000452127}; Flags: Fragment;"]
[1060,"'CENPC'",93,68,66,75.6666666666667,{"$nulls":4},"GO:0031618///nuclear pericentric heterochromatin+++GO:0000776///kinetochore+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0090543///Flemming body+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0030496///midbody+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0032154///cleavage furrow","GO:0003677///DNA binding+++GO:0019237///centromeric DNA binding","GO:0007059///chromosome segregation+++GO:0000278///mitotic cell cycle+++GO:0051455///attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation+++GO:0051382///kinetochore assembly+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division","centromere protein C","[CENPC_HUMAN|Reviewed]RecName: Full=Centromere protein C; Short=CENP-C; AltName: Full=Centromere autoantigen C; AltName: Full=Centromere protein C 1; Short=CENP-C 1; AltName: Full=Interphase centromere complex protein 7;"]
[10600,"'USP16'",348,313,278,313,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0035578///azurophil granule lumen+++GO:0070062///extracellular exosome+++GO:0044297///cell body+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0002199///zona pellucida receptor complex+++GO:0045111///intermediate filament cytoskeleton+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005874///microtubule+++GO:0034774///secretory granule lumen","GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0042393///histone binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0044183///protein binding involved in protein folding+++GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0043130///ubiquitin binding+++GO:0045296///cadherin binding+++GO:0005524///ATP binding+++GO:0042623///ATPase activity, coupled+++GO:0004197///cysteine-type endopeptidase activity+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0016578///histone deubiquitination+++GO:0045901///positive regulation of translational elongation+++GO:0000278///mitotic cell cycle+++GO:0046931///pore complex assembly+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061077///chaperone-mediated protein folding+++GO:0051726///regulation of cell cycle+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0051289///protein homotetramerization+++GO:0006351///transcription, DNA-templated+++GO:0043312///neutrophil degranulation+++GO:0051301///cell division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006458///'de novo' protein folding+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0140014///mitotic nuclear division+++GO:0016579///protein deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0007339///binding of sperm to zona pellucida","ubiquitin specific peptidase 16","[UBP16_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; EC=3.4.19.12 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Deubiquitinating enzyme 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin thioesterase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin-processing protease UBP-M; AltName: Full=Ubiquitin-specific-processing protease 16 {ECO:0000255|HAMAP-Rule:MF_03062};"]
[10602,"'CDC42EP3'",1914,1645,1287,1615.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system","GO:0005515///protein binding+++GO:0005519///cytoskeletal regulatory protein binding+++GO:0017049///GTP-Rho binding","GO:0008360///regulation of cell shape+++GO:0007165///signal transduction+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization","CDC42 effector protein 3","[BORG2_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 3; AltName: Full=Binder of Rho GTPases 2; AltName: Full=MSE55-related Cdc42-binding protein;+++[C9J7F7_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000398062}; Flags: Fragment;+++[C9JEZ4_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000403298}; Flags: Fragment;+++[C9JKW5_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000409147}; Flags: Fragment;"]
[10603,"'SH2B2'",80,88,82,83.3333333333333,"04910///Insulin signaling pathway+++04722///Neurotrophin signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0035591///signaling adaptor activity+++GO:0008236///serine-type peptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008269///JAK pathway signal transduction adaptor activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0016787///hydrolase activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0004252///serine-type endopeptidase activity","GO:0009967///positive regulation of signal transduction+++GO:0007165///signal transduction+++GO:0001922///B-1 B cell homeostasis+++GO:0006508///proteolysis+++GO:0007399///nervous system development+++GO:0046578///regulation of Ras protein signal transduction+++GO:0007596///blood coagulation+++GO:0050776///regulation of immune response+++GO:0008286///insulin receptor signaling pathway+++GO:0046425///regulation of JAK-STAT cascade+++GO:0050873///brown fat cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0019222///regulation of metabolic process","SH2B adaptor protein 2","[SH2B2_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 2; AltName: Full=Adapter protein with pleckstrin homology and Src homology 2 domains; AltName: Full=SH2 and PH domain-containing adapter protein APS;+++[A0A087X016_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000483034};+++[C9JK89_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000401883}; Flags: Fragment;+++[Q15098_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59997.1}; Flags: Fragment;+++[Q6LDS3_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59995.1}; Flags: Fragment;"]
[10605,"'PAIP1'",924,809,850,861,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0008494///translation activator activity+++GO:0003723///RNA binding","GO:0048255///mRNA stabilization+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0045727///positive regulation of translation+++GO:0006417///regulation of translation","poly(A) binding protein interacting protein 1","[PAIP1_HUMAN|Reviewed]RecName: Full=Polyadenylate-binding protein-interacting protein 1; Short=PABP-interacting protein 1; Short=PAIP-1; Short=Poly(A)-binding protein-interacting protein 1;+++[A0A024R094_HUMAN|Unreviewed]SubName: Full=Poly(A) binding protein interacting protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW56068.1};+++[A0A1D5RMS4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427410}; Flags: Fragment;+++[D6R9H8_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000422084};+++[D6RD97_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425406}; Flags: Fragment;+++[D6REB4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425084};+++[D6RJ02_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425736}; Flags: Fragment;+++[D6RJF2_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425675}; Flags: Fragment;+++[H0YA44_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000426089}; Flags: Fragment;"]
[10606,"'PAICS'",934,889,1117,980,"01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites",null,"M00048///Inosine monophosphate biosynthesis, PRPP + glutamine => IMP","R04209///1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase   1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2+++R04591///1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)   ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0045296///cadherin binding+++GO:0043727///5-amino-4-imidazole carboxylate lyase activity+++GO:0003824///catalytic activity+++GO:0004638///phosphoribosylaminoimidazole carboxylase activity+++GO:0016831///carboxy-lyase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity+++GO:0000166///nucleotide binding+++GO:0016829///lyase activity+++GO:0016874///ligase activity+++GO:0005515///protein binding","GO:0009113///purine nucleobase biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0008152///metabolic process+++GO:0006189///'de novo' IMP biosynthetic process","phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase","[PUR6_HUMAN|Reviewed]RecName: Full=Multifunctional protein ADE2; Includes: RecName: Full=Phosphoribosylaminoimidazole-succinocarboxamide synthase; EC=6.3.2.6; AltName: Full=SAICAR synthetase; Includes: RecName: Full=Phosphoribosylaminoimidazole carboxylase; EC=4.1.1.21; AltName: Full=AIR carboxylase; Short=AIRC;+++[A0A024RD93_HUMAN|Unreviewed]SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_c {ECO:0000313|EMBL:EAX05492.1};+++[D6RF62_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424907}; SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_b {ECO:0000313|EMBL:EAX05490.1};+++[E9PBS1_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424053}; Flags: Fragment;"]
[10607,"'TBL3'",647,766,677,696.666666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0005634///nucleus","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","transducin beta like 3","[TBL3_HUMAN|Reviewed]RecName: Full=Transducin beta-like protein 3; AltName: Full=WD repeat-containing protein SAZD;+++[A0A087WYP7_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000481995};+++[A0JLS5_HUMAN|Unreviewed]SubName: Full=TBL3 protein {ECO:0000313|EMBL:AAH07620.1}; Flags: Fragment;+++[H3BN88_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000454735};+++[J3KNP2_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000331815}; Flags: Fragment;"]
[10608,"'MXD4'",4227,4092,3697,4005.33333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008285///negative regulation of cell proliferation+++GO:0000122///negative regulation of transcription by RNA polymerase II","MAX dimerization protein 4","[MAD4_HUMAN|Reviewed]RecName: Full=Max dimerization protein 4; Short=Max dimerizer 4; AltName: Full=Class C basic helix-loop-helix protein 12; Short=bHLHc12; AltName: Full=Max-associated protein 4; AltName: Full=Max-interacting transcriptional repressor MAD4;+++[D3DVQ5_HUMAN|Unreviewed]SubName: Full=MAX dimerization protein 4, isoform CRA_e {ECO:0000313|EMBL:EAW82535.1};+++[D6RGV1_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000421209};+++[H0Y8Z5_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000422660}; Flags: Fragment;+++[Q7Z2R2_HUMAN|Unreviewed]SubName: Full=MSTP149 {ECO:0000313|EMBL:AAQ13695.1};"]
[10609,"'P3H4'",3799.98,4164.98,2988,3650.98666666667,{"$nulls":4},"GO:1902494///catalytic complex+++GO:0000794///condensed nuclear chromosome+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0000795///synaptonemal complex",null,"GO:0032964///collagen biosynthetic process+++GO:0030199///collagen fibril organization+++GO:0046849///bone remodeling+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0007130///synaptonemal complex assembly","prolyl 3-hydroxylase family member 4 (non-enzymatic)","[SC65_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653}; AltName: Full=Leprecan-like protein 4; AltName: Full=Nucleolar autoantigen No55 {ECO:0000303|PubMed:10952778, ECO:0000303|PubMed:8862517}; AltName: Full=Prolyl 3-hydroxylase family member 4 {ECO:0000312|HGNC:HGNC:16946}; AltName: Full=Synaptonemal complex protein SC65 {ECO:0000250|UniProtKB:Q64375}; Flags: Precursor;+++[H0YED7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000435615}; Flags: Fragment;+++[K7EJ03_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000464968}; Flags: Fragment;+++[K7ERA3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000468174}; Flags: Fragment;"]
[10610,"'ST6GALNAC2'",434,329,997,586.666666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008373///sialyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0016740///transferase activity","GO:0006486///protein glycosylation+++GO:0016266///O-glycan processing+++GO:0006493///protein O-linked glycosylation+++GO:0097503///sialylation+++GO:1990743///protein sialylation","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2","[SIA7B_HUMAN|Reviewed]RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; EC=2.4.99.3 {ECO:0000269|PubMed:10742600, ECO:0000269|PubMed:29251719}; AltName: Full=GalNAc alpha-2,6-sialyltransferase II; AltName: Full=ST6GalNAc II {ECO:0000303|PubMed:10742600}; Short=ST6GalNAcII {ECO:0000303|PubMed:29251719}; AltName: Full=SThM; AltName: Full=Sialyltransferase 7B; Short=SIAT7-B;+++[A0A024R8M1_HUMAN|Unreviewed]SubName: Full=ST6 (Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, isoform CRA_b {ECO:0000313|EMBL:EAW89418.1};+++[K7EIW2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000464915}; Flags: Fragment;+++[K7EKT8_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000465778};+++[K7EMI2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466513};+++[K7EMM1_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466560}; Flags: Fragment;"]
[10611,"'PDLIM5'",8065.01,5783.97,6759.01,6869.33,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005913///cell-cell adherens junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0098641///cadherin binding involved in cell-cell adhesion","GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0098609///cell-cell adhesion+++GO:0051963///regulation of synapse assembly+++GO:0061001///regulation of dendritic spine morphogenesis","PDZ and LIM domain 5","[PDLI5_HUMAN|Reviewed]RecName: Full=PDZ and LIM domain protein 5; AltName: Full=Enigma homolog; AltName: Full=Enigma-like PDZ and LIM domains protein;+++[A0A024RDE8_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain 5, isoform CRA_c {ECO:0000313|EMBL:EAX06057.1};+++[A0A0A0MSP3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000398469};+++[A0A0D9SFR4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486834}; Flags: Fragment;+++[A0A0D9SFW3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486938};+++[B7Z481_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54018, highly similar to PDZ and LIM domain protein 5 {ECO:0000313|EMBL:BAH12467.1};+++[B7Z8X5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61541, highly similar to Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 2, mRNA {ECO:0000313|EMBL:BAH14111.1};+++[D6RAA1_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000423009};+++[D6RGG6_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000426379};+++[H0Y8Y3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422528}; Flags: Fragment;+++[H0Y929_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422833}; Flags: Fragment;+++[H0YBI4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000429577}; Flags: Fragment;+++[Q4W5K9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LIM {ECO:0000313|EMBL:AAY40898.1}; Flags: Fragment;"]
[10612,"'TRIM3'",215,193,211,206.333333333333,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005769///early endosome+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0030425///dendrite","GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination","tripartite motif containing 3","[TRIM3_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 3; AltName: Full=Brain-expressed RING finger protein; AltName: Full=RING finger protein 22; AltName: Full=RING finger protein 97;+++[A0A1W2PPI7_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000491359};+++[B7Z5Y8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56028, highly similar to Tripartite motif-containing protein 3 {ECO:0000313|EMBL:BAH13074.1};+++[D3DQT3_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_d {ECO:0000313|EMBL:EAW68713.1}; Flags: Fragment;+++[D3DQT4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_f {ECO:0000313|EMBL:EAW68716.1}; Flags: Fragment;+++[E9PMK8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000433070}; Flags: Fragment;+++[E9PMW5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000437283}; Flags: Fragment;+++[L8EAL7_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM3 {ECO:0000313|EMBL:CCQ43796.1};"]
[10613,"'ERLIN1'",431,386,387,401.333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0015485///cholesterol binding","GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0008202///steroid metabolic process+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0032933///SREBP signaling pathway+++GO:0055085///transmembrane transport","ER lipid raft associated 1","[ERLN1_HUMAN|Reviewed]RecName: Full=Erlin-1; AltName: Full=Endoplasmic reticulum lipid raft-associated protein 1; AltName: Full=Protein KE04; AltName: Full=Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; Short=SPFH domain-containing protein 1;+++[B0QZ43_HUMAN|Unreviewed]SubName: Full=Erlin-1 {ECO:0000313|Ensembl:ENSP00000359436}; Flags: Fragment;+++[D3DR65_HUMAN|Unreviewed]SubName: Full=SPFH domain family, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW49847.1};"]
[10614,"'HEXIM1'",629,662,610,633.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0097322///7SK snRNA binding+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0017069///snRNA binding","GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045087///innate immune response+++GO:0007507///heart development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0002376///immune system process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002218///activation of innate immune response","hexamethylene bisacetamide inducible 1","[HEXI1_HUMAN|Reviewed]RecName: Full=Protein HEXIM1; AltName: Full=Cardiac lineage protein 1; AltName: Full=Estrogen down-regulated gene 1 protein; AltName: Full=Hexamethylene bis-acetamide-inducible protein 1; AltName: Full=Menage a quatre protein 1;+++[Q7L853_HUMAN|Unreviewed]SubName: Full=EDG1 {ECO:0000313|EMBL:AAK01993.1}; Flags: Fragment;"]
[10615,"'SPAG5'",26,27,17,23.3333333333333,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0034451///centriolar satellite+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton+++GO:0005694///chromosome+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0000777///condensed chromosome kinetochore+++GO:0005819///spindle+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0007059///chromosome segregation+++GO:0032388///positive regulation of intracellular transport+++GO:0007049///cell cycle+++GO:0000070///mitotic sister chromatid segregation+++GO:0090235///regulation of metaphase plate congression+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0007051///spindle organization+++GO:1905832///positive regulation of spindle assembly+++GO:0071539///protein localization to centrosome","sperm associated antigen 5","[SPAG5_HUMAN|Reviewed]RecName: Full=Sperm-associated antigen 5; AltName: Full=Astrin; AltName: Full=Deepest; AltName: Full=Mitotic spindle-associated protein p126; Short=MAP126;+++[A4FUA2_HUMAN|Unreviewed]SubName: Full=SPAG5 protein {ECO:0000313|EMBL:AAI13056.1}; Flags: Fragment;+++[F5GZT2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000444223}; Flags: Fragment;+++[J3KSV2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000462663};+++[J3KTQ0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000463095}; Flags: Fragment;+++[J3QRL6_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464280}; Flags: Fragment;+++[J3QRV8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464400};+++[J3QS12_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464474}; Flags: Fragment;+++[K7ELC8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466021}; Flags: Fragment;+++[K7ELG0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466061}; Flags: Fragment;"]
[10616,"'RBCK1'",1661,1755,1594,1670,"04217///Necroptosis+++04621///NOD-like receptor signaling pathway","H01744///Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis",null,null,"GO:0005829///cytosol+++GO:0071797///LUBAC complex","GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0060546///negative regulation of necroptotic process+++GO:0000209///protein polyubiquitination+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0097039///protein linear polyubiquitination+++GO:0050852///T cell receptor signaling pathway+++GO:0016032///viral process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling","RANBP2-type and C3HC4-type zinc finger containing 1","[HOIL1_HUMAN|Reviewed]RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1; EC=2.3.2.31 {ECO:0000269|PubMed:12629548}; AltName: Full=HBV-associated factor 4; AltName: Full=Heme-oxidized IRP2 ubiquitin ligase 1; Short=HOIL-1; AltName: Full=Hepatitis B virus X-associated protein 4; AltName: Full=RING finger protein 54; AltName: Full=RING-type E3 ubiquitin transferase HOIL-1 {ECO:0000305}; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 3;+++[A6PVJ5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000383106};+++[A6PVJ6_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000417173};+++[A6PVJ7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387799}; Flags: Fragment;+++[A6PVK0_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_b {ECO:0000313|EMBL:EAX10674.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371616};+++[B4DML5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405288}; SubName: Full=cDNA FLJ60704, highly similar to RanBP-type and C3HC4-type zincfinger-containing protein 1 {ECO:0000313|EMBL:BAG59927.1};+++[G3XAG9_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_d {ECO:0000313|EMBL:EAX10676.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371649};+++[H0Y4S7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000393841}; Flags: Fragment;+++[Q5JWR1_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000415080}; Flags: Fragment;"]
[10617,"'STAMBP'",968,836,959,921,"04144///Endocytosis","H01872///Microcephaly-capillary malformation syndrome",null,null,"GO:0005634///nucleus+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0070062///extracellular exosome+++GO:0032154///cleavage furrow+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008237///metallopeptidase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0019904///protein domain specific binding","GO:0046580///negative regulation of Ras protein signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0000281///mitotic cytokinesis+++GO:0007259///JAK-STAT cascade+++GO:0070536///protein K63-linked deubiquitination+++GO:0016579///protein deubiquitination+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0006508///proteolysis","STAM binding protein","[STABP_HUMAN|Reviewed]RecName: Full=STAM-binding protein; EC=3.4.19.-; AltName: Full=Associated molecule with the SH3 domain of STAM; AltName: Full=Endosome-associated ubiquitin isopeptidase;+++[A0A140VK54_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 54 {ECO:0000313|EMBL:AEE61191.1};+++[C9JEK5_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000390921}; Flags: Fragment;+++[C9JK83_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413874}; Flags: Fragment;+++[C9JZ93_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413291}; Flags: Fragment;+++[F5H5B9_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000443502};+++[L8ECD1_HUMAN|Unreviewed]SubName: Full=Alternative protein STAMBP {ECO:0000313|EMBL:CCQ43357.1};"]
[10618,"'TGOLN2'",4989,3911,3886,4262,"04137///Mitophagy - animal+++00830///Retinol metabolism+++04140///Autophagy - animal",null,null,"R07163///all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductas all-trans-13,14-Dihydroretinol + Acceptor <=> Retinol + Reduced acceptor","GO:0030140///trans-Golgi network transport vesicle+++GO:0005788///endoplasmic reticulum lumen+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0030133///transport vesicle+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0061024///membrane organization+++GO:0044267///cellular protein metabolic process","trans-golgi network protein 2","[TGON2_HUMAN|Reviewed]RecName: Full=Trans-Golgi network integral membrane protein 2; AltName: Full=TGN38 homolog; AltName: Full=TGN46; AltName: Full=TGN48; AltName: Full=Trans-Golgi network protein TGN51; Flags: Precursor;"]
[1062,"'CENPE'",13,2,4,6.33333333333333,null,"H00269///Primary microcephaly (MCPH)",null,null,"GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:0005828///kinetochore microtubule+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0000775///chromosome, centromeric region+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:1990023///mitotic spindle midzone+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0000779///condensed chromosome, centromeric region+++GO:0005874///microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005694///chromosome","GO:0005515///protein binding+++GO:0043515///kinetochore binding+++GO:0016887///ATPase activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0003777///microtubule motor activity","GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0045860///positive regulation of protein kinase activity+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0007275///multicellular organism development+++GO:0099606///microtubule plus-end directed mitotic chromosome migration+++GO:0099607///lateral attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division+++GO:0007059///chromosome segregation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0007049///cell cycle+++GO:0051382///kinetochore assembly+++GO:0007018///microtubule-based movement+++GO:0000278///mitotic cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore","centromere protein E","[CENPE_HUMAN|Reviewed]RecName: Full=Centromere-associated protein E; AltName: Full=Centromere protein E; Short=CENP-E; AltName: Full=Kinesin-7 {ECO:0000303|PubMed:25908662}; AltName: Full=Kinesin-related protein CENPE; Flags: Precursor;+++[A0A087X0P0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000483542};+++[D6RBW0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000423981}; Flags: Fragment;+++[D6RHK2_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000426023}; Flags: Fragment;"]
[10620,"'ARID3B'",113,97,95,101.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II","AT-rich interaction domain 3B","[ARI3B_HUMAN|Reviewed]RecName: Full=AT-rich interactive domain-containing protein 3B; Short=ARID domain-containing protein 3B; AltName: Full=Bright and dead ringer protein; AltName: Full=Bright-like protein;+++[H3BQ92_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 3B {ECO:0000313|Ensembl:ENSP00000455668}; Flags: Fragment;"]
[10621,"'POLR3F'",110,95,89,98,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding","GO:0002376///immune system process+++GO:0045089///positive regulation of innate immune response+++GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III","RNA polymerase III subunit F","[RPC6_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6; Short=RNA polymerase III subunit C6; AltName: Full=DNA-directed RNA polymerase III subunit F; AltName: Full=RNA polymerase III 39 kDa subunit; Short=RPC39;+++[L8EAI3_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3F {ECO:0000313|EMBL:CCQ43358.1};+++[Q05DB8_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763}; Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};"]
[10622,"'POLR3G'",12,9,10,10.3333333333333,"01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++05169///Epstein-Barr virus infection+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA","GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0002376///immune system process+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0045089///positive regulation of innate immune response+++GO:0008283///cell proliferation","RNA polymerase III subunit G","[RPC7_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC7; Short=RNA polymerase III subunit C7; AltName: Full=DNA-directed RNA polymerase III subunit G; AltName: Full=RNA polymerase III 32 kDa apha subunit; Short=RPC32-alpha {ECO:0000303|PubMed:20154270}; AltName: Full=RNA polymerase III 32 kDa subunit; Short=RPC32;+++[A0A024RAM1_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit {ECO:0000256|PIRNR:PIRNR000777};+++[D6R921_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422164}; Flags: Fragment;+++[D6R9U7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422892}; Flags: Fragment;+++[D6REQ0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000424970}; Flags: Fragment;+++[D6RIT0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000427412}; Flags: Fragment;+++[D6RJH6_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000425617};+++[L8E8B4_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3G {ECO:0000313|EMBL:CCQ43359.1};"]
[10623,"'POLR3C'",395,323,367,361.666666666667,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++00240///Pyrimidine metabolism+++03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex","GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003697///single-stranded DNA binding","GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0006351///transcription, DNA-templated+++GO:0051607///defense response to virus+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0002376///immune system process+++GO:0006383///transcription by RNA polymerase III","RNA polymerase III subunit C","[RPC3_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC3; Short=RNA polymerase III subunit C3; AltName: Full=DNA-directed RNA polymerase III subunit C; AltName: Full=RNA polymerase III 62 kDa subunit; Short=RPC62;+++[A0A024R4C1_HUMAN|Unreviewed]SubName: Full=Polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b {ECO:0000313|EMBL:EAW71436.1};+++[E9PHH9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000313|Ensembl:ENSP00000358300};+++[Q9BT08_HUMAN|Unreviewed]SubName: Full=POLR3C protein {ECO:0000313|EMBL:AAH04424.1};"]
[10625,"'IVNS1ABP'",7777,6493,5715,6661.66666666667,"05164///Influenza A",{"$nulls":3},"GO:0043025///neuronal cell body+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005743///mitochondrial inner membrane+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity","GO:0042493///response to drug+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0009615///response to virus+++GO:0006383///transcription by RNA polymerase III+++GO:0008380///RNA splicing+++GO:0055114///oxidation-reduction process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033194///response to hydroperoxide+++GO:0014070///response to organic cyclic compound+++GO:0016032///viral process","influenza virus NS1A binding protein",{"$cut":{"chars":32759,"head":"[NS1BP_HUMAN|Reviewed]RecName: Full=Influenza virus NS1A-binding protein; Short=NS1-BP; Short=NS1-binding protein {ECO:0000303|PubMed:9696811}; AltName: Full=Aryl hydrocarbon receptor-associated protein 3 {ECO:0000303|PubMed:16582008}; AltName: Full=Kelch-like protein 39 {ECO:0000303|PubMed:25619834};+++[A0A023I7N5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q5S8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q700_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q7R1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q875_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QC18_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QFT1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QG73_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QHN5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKB4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKQ2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QL98_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QMR7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QR60_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QRY9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QST8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QUI7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QW57_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QWQ3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXG8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXJ5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXT5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QYN1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QZ36_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0"}}]
[{"$cut":{"chars":32759,"head":"eductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B0W0B7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B0W1D4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B0W2W2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B0W6A1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B0WA42_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B1IIN8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B1PEM7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B1PEP1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1B1PEQ1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1J0PQP2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1J0PVD8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1J0PZI6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1J0Q567_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1J0QK96_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1L1ZDE4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1L1ZEQ7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1L1ZI05_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1L7NZB1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1L7NZD2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1L7NZE6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1S6LYZ9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1S6M5H7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1S6MN81_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1S6MXN3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A1S6NJA4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:00002"}}]
[{"$cut":{"chars":32759,"head":"}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[F5CUN0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[F5CV50_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[F6LHV0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[F6N708_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[F6N878_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G1K3W3_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase subunit 1 {ECO:0000313|EMBL:AEK94070.1}; Flags: Fragment;+++[G3C9Y1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G3CA07_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G3CA46_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G3EBI1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473}; Flags: Fragment;+++[G3M8J7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G3M8N6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G4W0U1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G4W2J6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G4W393_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G4W6N9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G5D7T0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G5D7U3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G5D821_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G5D886_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G5D8J0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G5D8K3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G5D8P2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G8JKS0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G9IFN4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[G9LB43_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:"}}]
["quinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q7YCD4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q7YCF4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q7YCG9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q7YED6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q7YEF7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q7YEG1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85BK7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85KT8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85KU3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85KU5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85KV8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85KW9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85KZ5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85L02_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q85L07_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q8HHH3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473}; Flags: Fragment;+++[Q8WCX2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q8WCX9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q94P91_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q9B1L5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q9B1M4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q9B2U3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q9B2V7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[Q9B2X4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473}; Flags: Fragment;+++[Q9B2X5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R4I9W6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y292_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y2E6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y3Q9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y4G3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y540_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y5D2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y5X1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y839_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9Y8K0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[R9YB54_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[S4SPU5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[S5RP67_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[T1Q620_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[T1SW94_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[T1WTX0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3KW55_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3L4L8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3L5A5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LB65_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LBX2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LBY6_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LD19_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LDT5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LDZ9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LS16_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U3LSH7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U5KQC8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U5YST9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U5YUT8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U5Z5R7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[U5ZBM2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V5JI67_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V5JIV5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V5JK95_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V5JS37_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V5JTW9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9H037_HUMAN|Unreviewed]SubName: Full=ND1 protein ( ND5protein ) {ECO:0000313|EMBL:AAB38368.1};+++[V9IVJ9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9J3V1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9JD42_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9JMR0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9JTA8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9JTR8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9JYE8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9K3G9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9K5S5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9M6T7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[V9N787_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[W8D6M0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[W8D794_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[X2C0V4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473}; Flags: Fragment;+++[X5BHN0_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[X5BIK3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[X5BKU3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[X6R674_HUMAN|Unreviewed]SubName: Full=Influenza virus NS1A-binding protein {ECO:0000313|Ensembl:ENSP00000356467};"]
[10626,"'TRIM16'",281.14,303.34,258.77,281.083333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016605///PML body","GO:0003676///nucleic acid binding+++GO:0032089///NACHT domain binding+++GO:0016740///transferase activity+++GO:0019966///interleukin-1 binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032526///response to retinoic acid+++GO:0060416///response to growth hormone+++GO:0043966///histone H3 acetylation+++GO:0046683///response to organophosphorus+++GO:0045618///positive regulation of keratinocyte differentiation","tripartite motif containing 16","[TRI16_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 16; AltName: Full=Estrogen-responsive B box protein;+++[B3KP96_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31464 fis, clone NT2NE2001337, highly similar to Tripartite motif-containing protein 16 {ECO:0000313|EMBL:BAG51608.1};+++[J3QKY5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463293}; Flags: Fragment;+++[J3QL38_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463360}; Flags: Fragment;+++[J3QLP0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463639};+++[J3QR69_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000464072}; Flags: Fragment;+++[K7EJH2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465169}; Flags: Fragment;+++[K7EL43_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465907}; Flags: Fragment;+++[K7ENN8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000467031}; Flags: Fragment;"]
[10627,"'MYL12A'",5122,5259,4684,5021.66666666667,"04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0016459///myosin complex","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0070527///platelet aggregation","myosin light chain 12A","[ML12A_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12A; AltName: Full=Epididymis secretory protein Li 24; Short=HEL-S-24; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3;+++[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;+++[J3KT92_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000462865}; Flags: Fragment;+++[J3KTJ1_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000463009}; Flags: Fragment;+++[J3QRS3_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000464359}; SubName: Full=Myosin regulatory light chain MRCL3, isoform CRA_b {ECO:0000313|EMBL:EAX01679.1};"]
[10628,"'TXNIP'",483,485,359,442.333333333333,"04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005758///mitochondrial intermembrane space+++GO:0005737///cytoplasm","GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0051782///negative regulation of cell division+++GO:0042127///regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0030216///keratinocyte differentiation+++GO:0006979///response to oxidative stress+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0043086///negative regulation of catalytic activity+++GO:0006606///protein import into nucleus+++GO:0051592///response to calcium ion+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0009612///response to mechanical stimulus+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0042542///response to hydrogen peroxide+++GO:0071228///cellular response to tumor cell","thioredoxin interacting protein","[TXNIP_HUMAN|Reviewed]RecName: Full=Thioredoxin-interacting protein; AltName: Full=Thioredoxin-binding protein 2; AltName: Full=Vitamin D3 up-regulated protein 1;+++[A0A024R4B7_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAW71411.1};+++[B1ALI9_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein {ECO:0000313|EMBL:CAI22352.1}; Flags: Fragment;+++[L8E7V6_HUMAN|Unreviewed]SubName: Full=Alternative protein TXNIP {ECO:0000313|EMBL:CCQ43360.1};"]
[10629,"'TAF6L'",201,188,159,182.666666666667,"05168///Herpes simplex infection+++03022///Basal transcription factors","H01879///Wiedemann-Steiner syndrome",null,null,"GO:0005669///transcription factor TFIID complex+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0046695///SLIK (SAGA-like) complex+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0000118///histone deacetylase complex","GO:0003713///transcription coactivator activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0004402///histone acetyltransferase activity","GO:0043966///histone H3 acetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006338///chromatin remodeling+++GO:0006366///transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006352///DNA-templated transcription, initiation+++GO:0006325///chromatin organization","TATA-box binding protein associated factor 6 like","[TAF6L_HUMAN|Reviewed]RecName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; AltName: Full=PCAF-associated factor 65-alpha; Short=PAF65-alpha;+++[A0A024R5A7_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_a {ECO:0000313|EMBL:EAW74094.1};+++[A8K0D4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78693, highly similar to Homo sapiens TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa (TAF6L), mRNA {ECO:0000313|EMBL:BAF82188.1};+++[B4DVM4_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW74095.1}; SubName: Full=cDNA FLJ57614, highly similar to TAF6-like RNA polymerase IIp300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|EMBL:BAG62736.1};+++[E9PK90_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435443};+++[E9PLV8_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435116}; Flags: Fragment;+++[E9PP94_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000434662}; Flags: Fragment;"]
[1063,"'CENPF'",54,42,35,43.6666666666667,null,"H01814///Stromme syndrome",null,null,"GO:0005930///axoneme+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0045120///pronucleus+++GO:0016363///nuclear matrix+++GO:0000776///kinetochore+++GO:0005635///nuclear envelope+++GO:0097539///ciliary transition fiber+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0030496///midbody+++GO:0005694///chromosome+++GO:0000940///condensed chromosome outer kinetochore+++GO:0000922///spindle pole+++GO:0000777///condensed chromosome kinetochore+++GO:0000775///chromosome, centromeric region","GO:0042803///protein homodimerization activity+++GO:0070840///dynein complex binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding","GO:0021591///ventricular system development+++GO:0001822///kidney development+++GO:0030154///cell differentiation+++GO:0007059///chromosome segregation+++GO:0007517///muscle organ development+++GO:0016202///regulation of striated muscle tissue development+++GO:0051310///metaphase plate congression+++GO:0042493///response to drug+++GO:0000278///mitotic cell cycle+++GO:0051301///cell division+++GO:0015031///protein transport+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0051382///kinetochore assembly+++GO:0071897///DNA biosynthetic process","centromere protein F","[CENPF_HUMAN|Reviewed]RecName: Full=Centromere protein F; Short=CENP-F; AltName: Full=AH antigen; AltName: Full=Kinetochore protein CENPF; AltName: Full=Mitosin; Flags: Precursor;+++[A0A087WTY4_HUMAN|Unreviewed]SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSP00000478221};"]
[10630,"'PDPN'",5107,5144,6103,5451.33333333333,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016323///basolateral plasma membrane+++GO:0071437///invadopodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0031528///microvillus membrane+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0061851///leading edge of lamellipodium+++GO:0001726///ruffle+++GO:0016324///apical plasma membrane+++GO:0031527///filopodium membrane+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0097197///tetraspanin-enriched microdomain+++GO:0045121///membrane raft+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0019956///chemokine binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005372///water transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0051087///chaperone binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity","GO:0044319///wound healing, spreading of cells+++GO:1901731///positive regulation of platelet aggregation+++GO:0001946///lymphangiogenesis+++GO:0060838///lymphatic endothelial cell fate commitment+++GO:0000902///cell morphogenesis+++GO:0003333///amino acid transmembrane transport+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0006833///water transport+++GO:0008360///regulation of cell shape+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:1904328///regulation of myofibroblast contraction+++GO:0008285///negative regulation of cell proliferation+++GO:0051272///positive regulation of cellular component movement+++GO:0015884///folic acid transport+++GO:0030335///positive regulation of cell migration+++GO:0070252///actin-mediated cell contraction+++GO:0030324///lung development+++GO:2000392///regulation of lamellipodium morphogenesis+++GO:0048535///lymph node development+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:1905863///invadopodium organization+++GO:0006865///amino acid transport+++GO:0043066///negative regulation of apoptotic process+++GO:0030168///platelet activation","podoplanin","[PDPN_HUMAN|Reviewed]RecName: Full=Podoplanin {ECO:0000303|Ref.9}; AltName: Full=Aggrus {ECO:0000303|Ref.3}; AltName: Full=Glycoprotein 36; Short=Gp36 {ECO:0000303|PubMed:10393083}; AltName: Full=PA2.26 antigen {ECO:0000303|PubMed:15515019}; AltName: Full=T1-alpha {ECO:0000250|UniProtKB:Q64294}; Short=T1A {ECO:0000250|UniProtKB:Q64294}; Contains: RecName: Full=29kDa cytosolic podoplanin intracellular domain {ECO:0000303|PubMed:24275092}; Short=PICD {ECO:0000303|PubMed:24275092}; Flags: Precursor;+++[D6RH07_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426210};+++[E7ETC6_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000422977};+++[H0Y8Q3_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000421742}; Flags: Fragment;+++[H0YA72_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426302};"]
[10631,"'POSTN'",11190,8571,5814,8525,{"$nulls":4},"GO:0005802///trans-Golgi network+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005615///extracellular space+++GO:0031594///neuromuscular junction+++GO:0062023///collagen-containing extracellular matrix","GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0046872///metal ion binding","GO:0071307///cellular response to vitamin K+++GO:0001666///response to hypoxia+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0009888///tissue development+++GO:0001501///skeletal system development+++GO:1904209///positive regulation of chemokine (C-C motif) ligand 2 secretion+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:0014850///response to muscle activity+++GO:1990138///neuron projection extension+++GO:0032355///response to estradiol+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030198///extracellular matrix organization+++GO:0008593///regulation of Notch signaling pathway+++GO:0042060///wound healing+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0007155///cell adhesion+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1990523///bone regeneration+++GO:0009612///response to mechanical stimulus+++GO:0003073///regulation of systemic arterial blood pressure","periostin","[POSTN_HUMAN|Reviewed]RecName: Full=Periostin; Short=PN; AltName: Full=Osteoblast-specific factor 2; Short=OSF-2; Flags: Precursor;+++[A0A024RDS2_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_c {ECO:0000313|EMBL:EAX08594.1};+++[A0A024RDT5_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_a {ECO:0000313|EMBL:EAX08591.1};+++[B1ALD9_HUMAN|Unreviewed]SubName: Full=Periostin {ECO:0000313|Ensembl:ENSP00000369073};"]
[10632,"'ATP5MG'",1121,1296,1258,1225,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane","GO:0015078///proton transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism","GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0015986///ATP synthesis coupled proton transport+++GO:0006811///ion transport","ATP synthase membrane subunit g","[ATP5L_HUMAN|Reviewed]RecName: Full=ATP synthase subunit g, mitochondrial {ECO:0000305}; Short=ATPase subunit g; AltName: Full=ATP synthase membrane subunit g {ECO:0000305};+++[E9PN17_HUMAN|Unreviewed]SubName: Full=ATP synthase membrane subunit g {ECO:0000313|Ensembl:ENSP00000434865};"]
[10633,"'RASL10A'",0,3,0,1,{"$nulls":4},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction","RAS like family 10 member A","[RSLAA_HUMAN|Reviewed]RecName: Full=Ras-like protein family member 10A; AltName: Full=Ras-like protein RRP22; AltName: Full=Ras-related protein on chromosome 22; Flags: Precursor;+++[A0A024R1C8_HUMAN|Unreviewed]SubName: Full=RAS-related on chromosome 22, isoform CRA_a {ECO:0000313|EMBL:EAW59797.1};+++[L8E9A0_HUMAN|Unreviewed]SubName: Full=Alternative protein RASL10A {ECO:0000313|EMBL:CCQ42928.1};"]
[10634,"'GAS2L1'",628,691,672,663.666666666667,{"$nulls":4},"GO:0005874///microtubule+++GO:0001725///stress fiber+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0046966///thyroid hormone receptor binding","GO:0001578///microtubule bundle formation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0009267///cellular response to starvation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0010629///negative regulation of gene expression+++GO:0051726///regulation of cell cycle+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest","growth arrest specific 2 like 1","[GA2L1_HUMAN|Reviewed]RecName: Full=GAS2-like protein 1; AltName: Full=GAS2-related protein on chromosome 22; AltName: Full=Growth arrest-specific protein 2-like 1;+++[A0A024R1J4_HUMAN|Unreviewed]SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_b {ECO:0000313|EMBL:EAW59794.1};+++[A0A5E8_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000478343}; SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_a {ECO:0000313|EMBL:EAW59788.1}; SubName: Full=cDNA FLJ16435 fis, clone BRACE3020671, highly similar to GAS2-like protein 1 {ECO:0000313|EMBL:BAG53749.1}; SubName: Full=cDNA FLJ36067 fis, clone TESTI2019308, highly similar to GAR22 PROTEIN {ECO:0000313|EMBL:BAC04150.1};+++[C9JFI0_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000395988}; Flags: Fragment;+++[C9JRR6_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000388645}; Flags: Fragment;"]
[10635,"'RAD51AP1'",10,14,6,10,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin","GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0006310///DNA recombination+++GO:0036297///interstrand cross-link repair+++GO:0071479///cellular response to ionizing radiation+++GO:0000724///double-strand break repair via homologous recombination+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006281///DNA repair","RAD51 associated protein 1","[R51A1_HUMAN|Reviewed]RecName: Full=RAD51-associated protein 1; AltName: Full=RAD51-interacting protein;+++[F5H031_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000438422};+++[F5H1Y0_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000446296};+++[F5H4V6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439925};+++[F5H710_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000442890};+++[H0YFK6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439019}; Flags: Fragment;+++[H0YGT5_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000444769}; Flags: Fragment;"]
[10636,"'RGS14'",241,332,348,307,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016604///nuclear body+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0043197///dendritic spine+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0000922///spindle pole+++GO:0030425///dendrite+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0032794///GTPase activating protein binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030695///GTPase regulator activity+++GO:0005515///protein binding","GO:0060291///long-term synaptic potentiation+++GO:0051301///cell division+++GO:0006913///nucleocytoplasmic transport+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007616///long-term memory+++GO:0008542///visual learning+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0007612///learning+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0000278///mitotic cell cycle+++GO:0007059///chromosome segregation+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0006979///response to oxidative stress+++GO:0050790///regulation of catalytic activity+++GO:0007165///signal transduction+++GO:0010070///zygote asymmetric cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0009968///negative regulation of signal transduction+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0050769///positive regulation of neurogenesis+++GO:0035556///intracellular signal transduction+++GO:0043407///negative regulation of MAP kinase activity","regulator of G protein signaling 14","[RGS14_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 14; Short=RGS14;+++[A0A024R7N4_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein signalling 14, isoform CRA_a {ECO:0000313|EMBL:EAW85013.1};+++[H0Y8W3_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein-signaling 14 {ECO:0000313|Ensembl:ENSP00000422329}; Flags: Fragment;"]
[10637,"'LEFTY1'",1.03,0,1.07,0.7,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005160///transforming growth factor beta receptor binding+++GO:0008083///growth factor activity+++GO:0005125///cytokine activity","GO:0060395///SMAD protein signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042981///regulation of apoptotic process+++GO:0003007///heart morphogenesis+++GO:0010469///regulation of signaling receptor activity+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0048468///cell development+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0007368///determination of left/right symmetry+++GO:0007275///multicellular organism development","left-right determination factor 1","[LFTY1_HUMAN|Reviewed]RecName: Full=Left-right determination factor 1; AltName: Full=Left-right determination factor B; AltName: Full=Protein lefty-1; AltName: Full=Protein lefty-B; Flags: Precursor;+++[A0A087WW09_HUMAN|Unreviewed]SubName: Full=Left-right determination factor 1 {ECO:0000313|Ensembl:ENSP00000479837}; Flags: Fragment;"]
[10638,"'SPHAR'",1.55,0,1.69,1.08,{"$nulls":6},"GO:0006260///DNA replication","S-phase response (cyclin related)","[SPHAR_HUMAN|Reviewed]RecName: Full=Protein SPHAR; AltName: Full=S-phase response protein;"]
[10640,"'EXOC5'",588,357,430,458.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0000145///exocyst+++GO:0030496///midbody+++GO:0005737///cytoplasm","GO:0047485///protein N-terminus binding+++GO:0005515///protein binding+++GO:0017160///Ral GTPase binding","GO:0048873///homeostasis of number of cells within a tissue+++GO:1905515///non-motile cilium assembly+++GO:1904019///epithelial cell apoptotic process+++GO:0001736///establishment of planar polarity+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0048278///vesicle docking+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport","exocyst complex component 5","[EXOC5_HUMAN|Reviewed]RecName: Full=Exocyst complex component 5; AltName: Full=Exocyst complex component Sec10; Short=hSec10;+++[A0A0A0MSI8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000389934};+++[F8W9B8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000342100};+++[G3V377_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000451082};+++[G3V4Z7_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000452084}; Flags: Fragment;"]
[10641,"'NPRL2'",374,385,330,363,"04150///mTOR signaling pathway",{"$nulls":3},"GO:1990130///GATOR1 complex+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0042802///identical protein binding+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042562///hormone binding+++GO:0005525///GTP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0017046///peptide hormone binding+++GO:0005096///GTPase activator activity+++GO:0000166///nucleotide binding+++GO:0004383///guanylate cyclase activity+++GO:0001653///peptide receptor activity+++GO:0004672///protein kinase activity+++GO:0016829///lyase activity+++GO:0016941///natriuretic peptide receptor activity","GO:2000785///regulation of autophagosome assembly+++GO:0060348///bone development+++GO:0033673///negative regulation of kinase activity+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:1900194///negative regulation of oocyte maturation+++GO:0022414///reproductive process+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0032007///negative regulation of TOR signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0006995///cellular response to nitrogen starvation+++GO:0034198///cellular response to amino acid starvation+++GO:0051447///negative regulation of meiotic cell cycle+++GO:1903779///regulation of cardiac conduction+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0001503///ossification+++GO:0019934///cGMP-mediated signaling+++GO:0010508///positive regulation of autophagy","NPR2 like, GATOR1 complex subunit","[NPRL2_HUMAN|Reviewed]RecName: Full=GATOR complex protein NPRL2 {ECO:0000305}; AltName: Full=Gene 21 protein {ECO:0000303|Ref.1}; Short=G21 protein {ECO:0000303|Ref.1}; AltName: Full=Nitrogen permease regulator 2-like protein {ECO:0000303|PubMed:11085536}; Short=NPR2-like protein {ECO:0000303|PubMed:11085536}; AltName: Full=Tumor suppressor candidate 4 {ECO:0000303|PubMed:18616680};+++[A6NJF2_HUMAN|Unreviewed]SubName: Full=Natriuretic peptide receptor B/guanylate cyclase B (Atrionatriuretic peptide receptor B) variant 3 {ECO:0000313|EMBL:ACA05922.1};+++[F2Z2R8_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000396172};+++[F2Z3D4_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000412779};+++[H7C056_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000393029}; Flags: Fragment;+++[H7C1A1_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000399204}; Flags: Fragment;+++[H7C1X0_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000402902}; Flags: Fragment;"]
[10642,"'IGF2BP1'",1146,927,959,1010.66666666667,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0010494///cytoplasmic stress granule+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003723///RNA binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0003692///left-handed Z-DNA binding+++GO:0042802///identical protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0003729///mRNA binding","GO:0010610///regulation of mRNA stability involved in response to stress+++GO:0097150///neuronal stem cell population maintenance+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0006403///RNA localization+++GO:0002376///immune system process+++GO:0006417///regulation of translation+++GO:0022013///pallium cell proliferation in forebrain+++GO:0017148///negative regulation of translation+++GO:0045087///innate immune response+++GO:0008150///biological_process+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0032479///regulation of type I interferon production+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0043488///regulation of mRNA stability+++GO:0032481///positive regulation of type I interferon production","insulin like growth factor 2 mRNA binding protein 1","[IF2B1_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 1; Short=IGF2 mRNA-binding protein 1; Short=IMP-1; Short=IMP1; AltName: Full=Coding region determinant-binding protein; Short=CRD-BP; AltName: Full=IGF-II mRNA-binding protein 1; AltName: Full=VICKZ family member 1; AltName: Full=Zipcode-binding protein 1; Short=ZBP-1;+++[D3DTW3_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP {ECO:0000313|EMBL:AKM97296.1}; SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94694.1};+++[L8ECD2_HUMAN|Unreviewed]SubName: Full=Alternative protein IGF2BP1 {ECO:0000313|EMBL:CCQ43362.1};"]
[10643,"'IGF2BP3'",620,494,476,530,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0048027///mRNA 5'-UTR binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability+++GO:0051028///mRNA transport+++GO:0017148///negative regulation of translation+++GO:0006412///translation+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0006417///regulation of translation","insulin like growth factor 2 mRNA binding protein 3","[IF2B3_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 3; Short=IGF2 mRNA-binding protein 3; Short=IMP-3; AltName: Full=IGF-II mRNA-binding protein 3; AltName: Full=KH domain-containing protein overexpressed in cancer; Short=hKOC; AltName: Full=VICKZ family member 3;+++[F8WD15_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000395936};"]
[10644,"'IGF2BP2'",1531,1138,1314,1327.66666666667,null,"H00409///Type II diabetes mellitus",null,null,"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability","insulin like growth factor 2 mRNA binding protein 2","[IF2B2_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 2; Short=IGF2 mRNA-binding protein 2; Short=IMP-2; AltName: Full=Hepatocellular carcinoma autoantigen p62; AltName: Full=IGF-II mRNA-binding protein 2; AltName: Full=VICKZ family member 2;+++[B3FTN5_HUMAN|Unreviewed]SubName: Full=Truncated insulin-like 2 growth factor 2-binding protein 2 {ECO:0000313|EMBL:ACB86628.1};+++[B4DKT5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53054, highly similar to Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|EMBL:BAG59297.1};+++[F8W930_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|Ensembl:ENSP00000410242};"]
[10645,"'CAMKK2'",624,550,603,592.333333333333,"04140///Autophagy - animal+++04152///AMPK signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04211///Longevity regulating pathway+++05034///Alcoholism",{"$nulls":3},"GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042995///cell projection","GO:0004683///calmodulin-dependent protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005516///calmodulin binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding","GO:0016310///phosphorylation+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0000165///MAPK cascade+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0006468///protein phosphorylation+++GO:0034614///cellular response to reactive oxygen species+++GO:0045859///regulation of protein kinase activity+++GO:0018108///peptidyl-tyrosine phosphorylation","calcium/calmodulin dependent protein kinase kinase 2","[KKCC2_HUMAN|Reviewed]RecName: Full=Calcium/calmodulin-dependent protein kinase kinase 2; Short=CaM-KK 2; Short=CaM-kinase kinase 2; Short=CaMKK 2; EC=2.7.11.17; AltName: Full=Calcium/calmodulin-dependent protein kinase kinase beta; Short=CaM-KK beta; Short=CaM-kinase kinase beta; Short=CaMKK beta;+++[A0A024RBP6_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_b {ECO:0000313|EMBL:EAW98251.1};+++[A0A024RBP8_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_d {ECO:0000313|EMBL:EAW98256.1};+++[A0A024RBQ0_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_f {ECO:0000313|EMBL:EAW98258.1};+++[A0A024RBQ3_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_e {ECO:0000313|EMBL:EAW98257.1};+++[F5GZ00_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000441352};+++[F5H360_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000445400}; Flags: Fragment;+++[F5H4I7_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000444894}; Flags: Fragment;+++[Q8IZW1_HUMAN|Unreviewed]SubName: Full=CAMKK beta protein {ECO:0000313|EMBL:AAN37388.1}; Flags: Fragment;"]
[10647,"'SCGB1D2'",4,8,11,7.66666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space",null,null,"secretoglobin family 1D member 2","[SG1D2_HUMAN|Reviewed]RecName: Full=Secretoglobin family 1D member 2; AltName: Full=Lipophilin-B; Flags: Precursor;"]
[10650,"'PRELID3A'",53,73,48,58,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0005515///protein binding+++GO:1990050///phosphatidic acid transporter activity","GO:0015914///phospholipid transport+++GO:0006869///lipid transport","PRELI domain containing 3A","[PLD3A_HUMAN|Reviewed]RecName: Full=PRELI domain containing protein 3A; AltName: Full=Protein slowmo homolog 1;+++[K7ELB4_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000465996}; Flags: Fragment;+++[K7ENN4_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467026};+++[K7EP78_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467261};+++[K7EPM9_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467457}; Flags: Fragment;+++[K7EQM5_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467896}; Flags: Fragment;"]
[10651,"'MTX2'",136,154,163,151,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006839///mitochondrial transport+++GO:0015031///protein transport","metaxin 2","[MTX2_HUMAN|Reviewed]RecName: Full=Metaxin-2; AltName: Full=Mitochondrial outer membrane import complex protein 2;+++[C9JAZ1_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000398757}; Flags: Fragment;+++[C9JNK6_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000414176};+++[F8WCW1_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000403545};+++[F8WE26_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000402204};"]
[10652,"'YKT6'",2212,2373,2038,2207.66666666667,"04138///Autophagy - yeast+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0097440///apical dendrite+++GO:0005783///endoplasmic reticulum+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0031201///SNARE complex+++GO:0005829///cytosol+++GO:0030133///transport vesicle+++GO:0005739///mitochondrion+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0097441///basal dendrite+++GO:0000139///Golgi membrane+++GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane","GO:0005484///SNAP receptor activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0061025///membrane fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0015031///protein transport+++GO:0006903///vesicle targeting+++GO:0016192///vesicle-mediated transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006888///ER to Golgi vesicle-mediated transport","YKT6 v-SNARE homolog","[YKT6_HUMAN|Reviewed]RecName: Full=Synaptobrevin homolog YKT6; EC=2.3.1.- {ECO:0000269|PubMed:15479160}; Flags: Precursor;+++[A4D2J0_HUMAN|Unreviewed]SubName: Full=SNARE protein Ykt6 {ECO:0000313|EMBL:EAL23763.1}; SubName: Full=SNARE protein Ykt6, isoform CRA_a {ECO:0000313|EMBL:EAW61111.1}; SubName: Full=cDNA, FLJ93006, Homo sapiens SNARE protein Ykt6 (YKT6), mRNA {ECO:0000313|EMBL:BAG35508.1};+++[B5BU81_HUMAN|Unreviewed]SubName: Full=YKT6 v-SNARE protein {ECO:0000313|EMBL:BAG70131.1};+++[H7C3K7_HUMAN|Unreviewed]SubName: Full=Synaptobrevin homolog YKT6 {ECO:0000313|Ensembl:ENSP00000412414}; Flags: Fragment;"]
[10653,"'SPINT2'",4080,4239,3123,3814,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane","GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:2000146///negative regulation of cell motility+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010466///negative regulation of peptidase activity+++GO:0060672///epithelial cell morphogenesis involved in placental branching+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0071711///basement membrane organization+++GO:0071773///cellular response to BMP stimulus+++GO:0007163///establishment or maintenance of cell polarity+++GO:0001843///neural tube closure","serine peptidase inhibitor, Kunitz type 2","[SPIT2_HUMAN|Reviewed]RecName: Full=Kunitz-type protease inhibitor 2; AltName: Full=Hepatocyte growth factor activator inhibitor type 2; Short=HAI-2; AltName: Full=Placental bikunin; Flags: Precursor;+++[A0A140VJV6_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 183 {ECO:0000313|EMBL:AEE61093.1};+++[K7EJS4_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465301}; Flags: Fragment;+++[K7EKC8_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465561}; Flags: Fragment;+++[K7EKQ0_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465721}; Flags: Fragment;+++[K7EM91_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000466407};+++[K7ES27_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000468519}; Flags: Fragment;+++[K7ESI5_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000468728}; Flags: Fragment;+++[Q6LEU8_HUMAN|Unreviewed]SubName: Full=SPINT2 protein {ECO:0000313|EMBL:CAG28532.1}; Flags: Fragment;"]
[10654,"'PMVK'",222,250,227,233,"00900///Terpenoid backbone biosynthesis+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++04146///Peroxisome","H01933///Porokeratosis","M00095///C5 isoprenoid biosynthesis, mevalonate pathway","R03245///ATP:(R)-5-phosphomevalonate phosphotransferase   ATP + (R)-5-Phosphomevalonate <=> ADP + (R)-5-Diphosphomevalonate","GO:0070062///extracellular exosome+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0004631///phosphomevalonate kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006629///lipid metabolic process+++GO:0070723///response to cholesterol+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0019287///isopentenyl diphosphate biosynthetic process, mevalonate pathway+++GO:0006694///steroid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0016310///phosphorylation+++GO:0008203///cholesterol metabolic process+++GO:0008202///steroid metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0006695///cholesterol biosynthetic process","phosphomevalonate kinase","[PMVK_HUMAN|Reviewed]RecName: Full=Phosphomevalonate kinase; Short=PMKase; Short=hPMK; EC=2.7.4.2;+++[Q6FGV9_HUMAN|Unreviewed]SubName: Full=PMVK protein {ECO:0000313|EMBL:CAG46795.1}; SubName: Full=Phosphomevalonate kinase, isoform CRA_a {ECO:0000313|EMBL:EAW53177.1}; SubName: Full=Testis tissue sperm-binding protein Li 95mP {ECO:0000313|EMBL:AEE61315.1}; SubName: Full=cDNA, FLJ93228, Homo sapiens phosphomevalonate kinase (PMVK), mRNA {ECO:0000313|EMBL:BAG35661.1}; Flags: Fragment;"]
[10656,"'KHDRBS3'",220,253,197,223.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0019904///protein domain specific binding+++GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0051259///protein complex oligomerization+++GO:0006397///mRNA processing+++GO:0048024///regulation of mRNA splicing, via spliceosome","KH RNA binding domain containing, signal transduction associated 3","[KHDR3_HUMAN|Reviewed]RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3; AltName: Full=RNA-binding protein T-Star; AltName: Full=Sam68-like mammalian protein 2; Short=SLM-2; AltName: Full=Sam68-like phosphotyrosine protein;+++[E5RG12_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000430284}; Flags: Fragment;+++[E5RHD3_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000428607};+++[E5RJZ9_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000431022}; Flags: Fragment;+++[H0YAQ1_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000427841}; Flags: Fragment;+++[H0YAQ3_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000427851}; Flags: Fragment;+++[H0YB45_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000428643}; Flags: Fragment;+++[L8EAJ0_HUMAN|Unreviewed]SubName: Full=Alternative protein KHDRBS3 {ECO:0000313|EMBL:CCQ43363.1};+++[L8EC47_HUMAN|Unreviewed]SubName: Full=Alternative protein KHDRBS3 {ECO:0000313|EMBL:CCQ42937.1};"]
[10657,"'KHDRBS1'",1515,1279,1279,1357.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070618///Grb2-Sos complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0008266///poly(U) RNA binding+++GO:0003676///nucleic acid binding+++GO:0042802///identical protein binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0003677///DNA binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019904///protein domain specific binding+++GO:0008143///poly(A) binding+++GO:0003723///RNA binding","GO:0007049///cell cycle+++GO:0031647///regulation of protein stability+++GO:0045948///positive regulation of translational initiation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006397///mRNA processing+++GO:0007165///signal transduction+++GO:0046831///regulation of RNA export from nucleus+++GO:0007166///cell surface receptor signaling pathway+++GO:0007050///cell cycle arrest+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0008283///cell proliferation+++GO:0007283///spermatogenesis+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0051259///protein complex oligomerization+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0009967///positive regulation of signal transduction+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","KH RNA binding domain containing, signal transduction associated 1","[KHDR1_HUMAN|Reviewed]RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 1; AltName: Full=GAP-associated tyrosine phosphoprotein p62; AltName: Full=Src-associated in mitosis 68 kDa protein; Short=Sam68; AltName: Full=p21 Ras GTPase-activating protein-associated p62; AltName: Full=p68;+++[B4E043_HUMAN|Unreviewed]SubName: Full=KH domain containing, RNA binding, signal transduction associated 1, isoform CRA_b {ECO:0000313|EMBL:EAX07575.1}; SubName: Full=cDNA FLJ52899, highly similar to KH domain-containing, RNA-binding, signaltransduction-associated protein 1 {ECO:0000313|EMBL:BAG64305.1};"]
[10658,"'CELF1'",608,379,536,507.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0042835///BRE binding+++GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0005515///protein binding+++GO:0036002///pre-mRNA binding+++GO:0003676///nucleic acid binding+++GO:0031369///translation initiation factor binding","GO:0007281///germ cell development+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0017148///negative regulation of translation+++GO:0006376///mRNA splice site selection+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0040018///positive regulation of multicellular organism growth+++GO:0016246///RNA interference+++GO:0008380///RNA splicing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0007286///spermatid development","CUGBP Elav-like family member 1","[CELF1_HUMAN|Reviewed]RecName: Full=CUGBP Elav-like family member 1; Short=CELF-1; AltName: Full=50 kDa nuclear polyadenylated RNA-binding protein; AltName: Full=Bruno-like protein 2; AltName: Full=CUG triplet repeat RNA-binding protein 1; Short=CUG-BP1; AltName: Full=CUG-BP- and ETR-3-like factor 1; AltName: Full=Deadenylation factor CUG-BP; AltName: Full=Embryo deadenylation element-binding protein homolog; Short=EDEN-BP homolog; AltName: Full=RNA-binding protein BRUNOL-2;+++[E9PKA1_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000435423}; Flags: Fragment;+++[E9PKU1_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000435320}; Flags: Fragment;+++[E9PQK4_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000436191}; Flags: Fragment;+++[E9PSH0_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000433986}; Flags: Fragment;+++[F5H0D8_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000438044}; Flags: Fragment;+++[F5H3J7_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000438862}; Flags: Fragment;+++[F5H4Y5_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000444825}; Flags: Fragment;+++[F5H7M7_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000442415}; Flags: Fragment;+++[G5EA30_HUMAN|Unreviewed]SubName: Full=CUG triplet repeat, RNA binding protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW67908.1}; SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000436864};"]
[10659,"'CELF2'",1650,1299,1477,1475.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus","GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0036002///pre-mRNA binding","GO:0006397///mRNA processing+++GO:0008016///regulation of heart contraction+++GO:0006376///mRNA splice site selection+++GO:0006396///RNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","CUGBP Elav-like family member 2","[CELF2_HUMAN|Reviewed]RecName: Full=CUGBP Elav-like family member 2; Short=CELF-2; AltName: Full=Bruno-like protein 3; AltName: Full=CUG triplet repeat RNA-binding protein 2; Short=CUG-BP2; AltName: Full=CUG-BP- and ETR-3-like factor 2; AltName: Full=ELAV-type RNA-binding protein 3; Short=ETR-3; AltName: Full=Neuroblastoma apoptosis-related RNA-binding protein; Short=hNAPOR; AltName: Full=RNA-binding protein BRUNOL-3;+++[A0A0J9YX66_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000488268};+++[A0A0J9YXJ0_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000488422};+++[A0A0J9YXK1_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000488438};+++[A0A1B0GU44_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000489955};+++[A0A1B0GUN8_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000490185};+++[B4DDE7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54335, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG56708.1};+++[B4DIB6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51739, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG58428.1};+++[B4DT00_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50655, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG61812.1};+++[B4DZ01_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52370, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG63913.1};+++[E9PC62_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000443926};+++[Q5VZZ6_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000346971};+++[V9GY47_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000476392};+++[V9GYD9_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000476656};"]
[1066,"'CES1'",17,19,21,19,"01100///Metabolic pathways+++00983///Drug metabolism - other enzymes",null,null,"R08251///isoniazid amidohydrolase   Isoniazid + H2O <=> Isonicotinic acid + Hydrazine+++R06728///cocaine benzoylhydrolase   Cocaine + H2O <=> Ecgonine methyl ester + Benzoate+++R08258///NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid+++R08249///N-acetylisoniazid amidohydrolase   N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid+++R08255///Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid+++R08220///capecitabine hydrolase   Capecitabine + H2O <=> 5'-Deoxy-5-fluorocytidine + 1-Pentanol + CO2","GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen","GO:0016787///hydrolase activity+++GO:0004806///triglyceride lipase activity+++GO:0004771///sterol esterase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0047374///methylumbelliferyl-acetate deacetylase activity","GO:0006805///xenobiotic metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0051791///medium-chain fatty acid metabolic process+++GO:0009056///catabolic process+++GO:0090122///cholesterol ester hydrolysis involved in cholesterol transport+++GO:0009636///response to toxic substance+++GO:0030855///epithelial cell differentiation+++GO:0016042///lipid catabolic process","carboxylesterase 1","[EST1_HUMAN|Reviewed]RecName: Full=Liver carboxylesterase 1; AltName: Full=Acyl-coenzyme A:cholesterol acyltransferase; Short=ACAT; AltName: Full=Brain carboxylesterase hBr1; AltName: Full=Carboxylesterase 1; Short=CE-1; Short=hCE-1; EC=3.1.1.1 {ECO:0000269|PubMed:7980644, ECO:0000269|PubMed:9169443, ECO:0000269|PubMed:9490062}; AltName: Full=Cocaine carboxylesterase; AltName: Full=Egasyn; AltName: Full=HMSE; AltName: Full=Methylumbelliferyl-acetate deacetylase 1; EC=3.1.1.56 {ECO:0000269|PubMed:9169443}; AltName: Full=Monocyte/macrophage serine esterase; AltName: Full=Retinyl ester hydrolase; Short=REH; AltName: Full=Serine esterase 1; AltName: Full=Triacylglycerol hydrolase; Short=TGH; Flags: Precursor;+++[A0A140TA63_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000458773}; Flags: Fragment;+++[H3BQR4_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000455902}; Flags: Fragment;+++[H3BQV8_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000455959}; Flags: Fragment;+++[H3BSU0_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000456865}; Flags: Fragment;"]
[10664,"'CTCF'",531,469,440,480,{"$nulls":4},"GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0000775///chromosome, centromeric region","GO:0044212///transcription regulatory region DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003714///transcription corepressor activity+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0043035///chromatin insulator sequence binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0008285///negative regulation of cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006325///chromatin organization+++GO:0035065///regulation of histone acetylation+++GO:0040030///regulation of molecular function, epigenetic+++GO:0010216///maintenance of DNA methylation+++GO:0070602///regulation of centromeric sister chromatid cohesion+++GO:0006306///DNA methylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0040029///regulation of gene expression, epigenetic+++GO:0031060///regulation of histone methylation+++GO:0010629///negative regulation of gene expression+++GO:0016584///nucleosome positioning+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0007059///chromosome segregation","CCCTC-binding factor","[CTCF_HUMAN|Reviewed]RecName: Full=Transcriptional repressor CTCF; AltName: Full=11-zinc finger protein; AltName: Full=CCCTC-binding factor; AltName: Full=CTCFL paralog;+++[A0A2R8Y595_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000494358};+++[A0A2R8Y6C1_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000495115}; Flags: Fragment;+++[A0A2R8Y6Z6_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000495923}; Flags: Fragment;+++[A0A2R8YFL0_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000495218};"]
[10666,"'CD226'",1,1,0,0.666666666666667,"04514///Cell adhesion molecules (CAMs)","H00408///Type I diabetes mellitus",null,null,"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0009897///external side of plasma membrane+++GO:0045121///membrane raft+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005178///integrin binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding","GO:0032729///positive regulation of interferon-gamma production+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0007165///signal transduction+++GO:0060369///positive regulation of Fc receptor mediated stimulatory signaling pathway+++GO:0001816///cytokine production+++GO:0007155///cell adhesion+++GO:0002891///positive regulation of immunoglobulin mediated immune response+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0050776///regulation of immune response+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0033005///positive regulation of mast cell activation+++GO:0008037///cell recognition+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity","CD226 molecule","[CD226_HUMAN|Reviewed]RecName: Full=CD226 antigen; AltName: Full=DNAX accessory molecule 1; Short=DNAM-1; AltName: CD_antigen=CD226; Flags: Precursor;+++[J3QKM7_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000463152}; Flags: Fragment;+++[J3QL19_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000463335}; Flags: Fragment;+++[J3QQW1_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000463927}; Flags: Fragment;+++[J3QR77_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000464084};+++[J3QRQ4_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000464334}; Flags: Fragment;"]
[10667,"'FARS2'",173,187,195,185,"00970///Aminoacyl-tRNA biosynthesis","H00266///Hereditary spastic paraplegia (SPG)+++H00891///Combined oxidative phosphorylation deficiency (COXPD)","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm","GO:0016874///ligase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000049///tRNA binding+++GO:0004826///phenylalanine-tRNA ligase activity","GO:0006418///tRNA aminoacylation for protein translation+++GO:0006412///translation+++GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0008033///tRNA processing","phenylalanyl-tRNA synthetase 2, mitochondrial","[SYFM_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase, mitochondrial; EC=6.1.1.20 {ECO:0000269|PubMed:19549855, ECO:0000269|PubMed:22833457}; AltName: Full=Phenylalanyl-tRNA synthetase; Short=PheRS; Flags: Precursor;+++[Q5JRF7_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000392525}; Flags: Fragment;+++[R4GMX6_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000473394}; Flags: Fragment;"]
[106865373,"'WRB-SH3BGR'",15.61,22.38,3.79,13.9266666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane","GO:0017124///SH3 domain binding+++GO:0005070///SH3/SH2 adaptor activity","GO:0065003///protein-containing complex assembly+++GO:0071816///tail-anchored membrane protein insertion into ER membrane","WRB-SH3BGR readthrough","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[MOST1_HUMAN|diamond]RecName: Full=Protein MOST-1;+++[SH3BG_HUMAN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich protein; Short=SH3BGR protein; AltName: Full=21-glutamic acid-rich protein; Short=21-GARP;+++[SH3BG_MOUSE|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich protein; Short=SH3BGR protein;+++[SH3L1_BOVIN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_HUMAN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_MACFA|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_PONAB|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[WRB_BOVIN|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[WRB_HUMAN|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Congenital heart disease 5 protein; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[WRB_PONAB|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN701_HUMAN|diamond]RecName: Full=Zinc finger protein 701;"]
[10728,"'PTGES3'",1532,1405,1445,1460.66666666667,"01100///Metabolic pathways+++00590///Arachidonic acid metabolism",null,null,"R02265///(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase   Prostaglandin H2 <=> Prostaglandin E2","GO:0005697///telomerase holoenzyme complex+++GO:0101031///chaperone complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm","GO:0051879///Hsp90 protein binding+++GO:0016853///isomerase activity+++GO:0050220///prostaglandin-E synthase activity+++GO:0005515///protein binding+++GO:0003720///telomerase activity+++GO:0051082///unfolded protein binding+++GO:0070182///DNA polymerase binding+++GO:0051087///chaperone binding","GO:0019371///cyclooxygenase pathway+++GO:0006629///lipid metabolic process+++GO:0001516///prostaglandin biosynthetic process+++GO:0006805///xenobiotic metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0050821///protein stabilization+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0007004///telomere maintenance via telomerase+++GO:0000723///telomere maintenance+++GO:1905323///telomerase holoenzyme complex assembly+++GO:0006631///fatty acid metabolic process+++GO:0006457///protein folding+++GO:0006693///prostaglandin metabolic process+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:1900034///regulation of cellular response to heat+++GO:0007165///signal transduction+++GO:0042327///positive regulation of phosphorylation+++GO:0051973///positive regulation of telomerase activity","prostaglandin E synthase 3","[TEBP_HUMAN|Reviewed]RecName: Full=Prostaglandin E synthase 3; EC=5.3.99.3 {ECO:0000269|PubMed:10922363}; AltName: Full=Cytosolic prostaglandin E2 synthase; Short=cPGES; AltName: Full=Hsp90 co-chaperone; AltName: Full=Progesterone receptor complex p23; AltName: Full=Telomerase-binding protein p23;+++[A0A024RB32_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 (Cytosolic), isoform CRA_a {ECO:0000313|EMBL:EAW96957.1};+++[A0A087WYT3_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 {ECO:0000313|Ensembl:ENSP00000482075};+++[B3KUY2_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 (Cytosolic), isoform CRA_c {ECO:0000313|EMBL:EAW96955.1}; SubName: Full=cDNA FLJ40895 fis, clone UTERU2002294, highly similar to Prostaglandin E synthase 3 {ECO:0000313|EMBL:BAG53594.1};+++[B4DDC6_HUMAN|Unreviewed]SubName: Full=Prostaglandin E synthase 3 {ECO:0000313|Ensembl:ENSP00000389090}; SubName: Full=cDNA FLJ59832, moderately similar to Prostaglandin E synthase 3 {ECO:0000313|EMBL:BAG56687.1};"]
[10734,"'STAG3'",23,16.03,17.02,18.6833333333333,"04114///Oocyte meiosis",{"$nulls":3},"GO:0000800///lateral element+++GO:0000795///synaptonemal complex+++GO:0030893///meiotic cohesin complex+++GO:0000794///condensed nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0001673///male germ cell nucleus+++GO:0000802///transverse filament+++GO:0005615///extracellular space+++GO:0005694///chromosome+++GO:0034991///nuclear meiotic cohesin complex","GO:0003682///chromatin binding+++GO:0005515///protein binding","GO:0051321///meiotic cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0007059///chromosome segregation+++GO:0007049///cell cycle+++GO:0007129///synapsis+++GO:0034502///protein localization to chromosome","stromal antigen 3","[STAG3_HUMAN|Reviewed]RecName: Full=Cohesin subunit SA-3; AltName: Full=SCC3 homolog 3; AltName: Full=Stromal antigen 3; AltName: Full=Stromalin-3;+++[B2RU25_HUMAN|Unreviewed]SubName: Full=Stromal antigen 3 {ECO:0000313|EMBL:AAI40933.1};+++[C9J3T3_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000397067}; Flags: Fragment;+++[C9JTG4_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000409283}; Flags: Fragment;+++[C9JYW5_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000407884}; Flags: Fragment;+++[D6W5U7_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000477973}; SubName: Full=HCG2024106, isoform CRA_c {ECO:0000313|EMBL:EAW76572.1};+++[H0Y4S6_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000393790}; Flags: Fragment;+++[H7C0H6_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000395039}; Flags: Fragment;"]
[10775,"'POP4'",353,352,334,346.333333333333,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0000172///ribonuclease MRP complex+++GO:0030677///ribonuclease P complex+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0030681///multimeric ribonuclease P complex","GO:0033204///ribonuclease P RNA binding+++GO:0003723///RNA binding+++GO:0004526///ribonuclease P activity","GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0006364///rRNA processing","POP4 homolog, ribonuclease P/MRP subunit","[RPP29_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p29; Short=hPOP4; EC=3.1.26.5;"]
[10782,"'ZNF274'",392,341,375,369.333333333333,"04722///Neurotrophin signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0003714///transcription corepressor activity","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:1900112///regulation of histone H3-K9 trimethylation+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 274","[ZN274_HUMAN|Reviewed]RecName: Full=Neurotrophin receptor-interacting factor homolog; AltName: Full=Zinc finger protein 274; AltName: Full=Zinc finger protein HFB101; AltName: Full=Zinc finger protein with KRAB and SCAN domains 19; AltName: Full=Zinc finger protein zfp2; Short=Zf2;+++[A0A0A0MR47_HUMAN|Unreviewed]SubName: Full=Neurotrophin receptor-interacting factor homolog {ECO:0000313|Ensembl:ENSP00000321209};+++[M0QXW4_HUMAN|Unreviewed]SubName: Full=Neurotrophin receptor-interacting factor homolog {ECO:0000313|Ensembl:ENSP00000469427}; Flags: Fragment;+++[M0QY30_HUMAN|Unreviewed]SubName: Full=Neurotrophin receptor-interacting factor homolog {ECO:0000313|Ensembl:ENSP00000469546}; Flags: Fragment;"]
[107984203,"'LOC107984203'",41.86,47.01,57.5,48.79,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0008270///zinc ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003677///DNA binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity","GO:0006310///DNA recombination+++GO:0015074///DNA integration","endogenous retrovirus group K member 6 Env polyprotein","[PO113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pol protein; AltName: Full=HERV-K113 Pol protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Pol protein; AltName: Full=HERV-K(C19) Pol protein; AltName: Full=HERV-K_19q11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;"]
[107984314,"'LOC107984314'",8.48,4.44,4.52,5.81333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"uncharacterized LOC107984314","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[107984820,"'107984820'",0,1,0,0.333333333333333,{"$nulls":8},"[Q6ZNS3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ27243 fis, clone SYN08134 {ECO:0000313|EMBL:BAC85422.1};"]
[107985657,"'LOC107985657'",1,0,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC107985657","[H2PUX8_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000022518};"]
[107986163,"'LOC107986163'",141.01,125,148,138.003333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0016567///protein ubiquitination+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070895///negative regulation of transposon integration+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0006351///transcription, DNA-templated","uncharacterized LOC107986163","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[MAGF1_HUMAN|diamond]RecName: Full=Melanoma-associated antigen F1 {ECO:0000305}; Short=MAGE-F1 {ECO:0000303|PubMed:11313144, ECO:0000303|PubMed:29225034}; AltName: Full=MAGE-F1 antigen;+++[NANGN_HUMAN|diamond]RecName: Full=NANOG neighbor homeobox; AltName: Full=Homeobox protein C14;+++[NSE3_HUMAN|diamond]RecName: Full=Non-structural maintenance of chromosomes element 3 homolog; Short=Non-SMC element 3 homolog; AltName: Full=Hepatocellular carcinoma-associated protein 4; AltName: Full=MAGE-G1 antigen; AltName: Full=Melanoma-associated antigen G1; AltName: Full=Necdin-like protein 2;+++[NSE3_MOUSE|diamond]RecName: Full=Non-structural maintenance of chromosomes element 3 homolog; Short=Non-SMC element 3 homolog; AltName: Full=MAGE-G1 antigen; AltName: Full=Necdin-like protein 2;+++[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[PKP2_HUMAN|diamond]RecName: Full=Plakophilin-2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;+++[ZNF91_HUMAN|diamond]RecName: Full=Zinc finger protein 91; AltName: Full=Zinc finger protein HPF7; AltName: Full=Zinc finger protein HTF10;"]
[107986801,"'107986801'",7.82,5.65,11.23,8.23333333333333,{"$nulls":8},"[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[107987254,"'LOC107987254'",4,5,4,4.33333333333333,{"$nulls":7},"uncharacterized protein FAM215A-like","[F215A_HUMAN|diamond]RecName: Full=Uncharacterized protein FAM215A; AltName: Full=Apoptosis-related protein 2; Short=APR-2;+++[MKNK1_HUMAN|diamond]RecName: Full=MAP kinase-interacting serine/threonine-protein kinase 1; EC=2.7.11.1 {ECO:0000269|PubMed:11463832, ECO:0000269|PubMed:9155018}; AltName: Full=MAP kinase signal-integrating kinase 1; Short=MAPK signal-integrating kinase 1; Short=Mnk1;"]
[107987464,"'LOC107987464'",71.19,71.74,58.27,67.0666666666667,"00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse+++00980///Metabolism of xenobiotics by cytochrome P450+++01522///Endocrine resistance","H01171///Poor drug metabolism (PM)",null,"R08270///N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O+++R09421///4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP++++R08345///Demethylcitalopram <=> Didemethylcitalopram+++R08343///Citalopram <=> Demethylcitalopram+++R08344///Citalopram <=> Citalopram N-oxide+++R03697///Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen+++R08267///Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O","GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0031090///organelle membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0042802///identical protein binding+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0070330///aromatase activity+++GO:0004497///monooxygenase activity+++GO:0020037///heme binding+++GO:0016491///oxidoreductase activity+++GO:0005506///iron ion binding+++GO:0008395///steroid hydroxylase activity+++GO:0042803///protein homodimerization activity+++GO:0008144///drug binding+++GO:0070694///deoxyribonucleoside 5'-monophosphate N-glycosidase activity","GO:0030307///positive regulation of cell growth+++GO:0090350///negative regulation of cellular organofluorine metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0017144///drug metabolic process+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0009159///deoxyribonucleoside monophosphate catabolic process+++GO:0009822///alkaloid catabolic process+++GO:0009820///alkaloid metabolic process+++GO:0051100///negative regulation of binding+++GO:0006195///purine nucleotide catabolic process+++GO:0055114///oxidation-reduction process+++GO:0046483///heterocycle metabolic process+++GO:0070989///oxidative demethylation+++GO:0042738///exogenous drug catabolic process+++GO:0033076///isoquinoline alkaloid metabolic process+++GO:0009804///coumarin metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0008283///cell proliferation+++GO:0009116///nucleoside metabolic process+++GO:0042737///drug catabolic process+++GO:0008202///steroid metabolic process+++GO:0016098///monoterpenoid metabolic process+++GO:0030855///epithelial cell differentiation","uncharacterized LOC107987464","[CE017_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C5orf17;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CP2D6_HUMAN|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000269|PubMed:21576599}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000305|PubMed:21576599}; AltName: Full=Cytochrome P450-DB1; AltName: Full=Debrisoquine 4-hydroxylase;+++[CP2D6_PANPA|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D6_PANTR|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D7_HUMAN|diamond]RecName: Full=Putative cytochrome P450 2D7 {ECO:0000305}; EC=1.14.14.1 {ECO:0000269|PubMed:15051713};+++[CP2DH_MACFA|diamond]RecName: Full=Cytochrome P450 2D17; EC=1.14.14.1; AltName: Full=CYPIID17;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DNPH1_DANRE|diamond]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036};+++[DNPH1_ESOLU|diamond]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036};+++[DNPH1_HUMAN|diamond]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036, ECO:0000269|PubMed:24260472, ECO:0000269|PubMed:25108359}; AltName: Full=c-Myc-responsive protein RCL {ECO:0000255|HAMAP-Rule:MF_03036};+++[DNPH1_MOUSE|diamond]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036}; AltName: Full=c-Myc-responsive protein Rcl {ECO:0000255|HAMAP-Rule:MF_03036};+++[DNPH1_RAT|diamond]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036, ECO:0000269|PubMed:17234634, ECO:0000269|PubMed:19822152, ECO:0000269|PubMed:24260472, ECO:0000269|PubMed:25108359}; AltName: Full=Deoxyribonucleoside 5'-monophosphate N-glycosidase; AltName: Full=c-Myc-responsive protein Rcl {ECO:0000255|HAMAP-Rule:MF_03036};+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[NC336_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00336;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10802,"'SEC24A'",1107,642,827,858.666666666667,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat+++GO:0031410///cytoplasmic vesicle+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0048208///COPII vesicle coating+++GO:0016192///vesicle-mediated transport+++GO:0050714///positive regulation of protein secretion+++GO:0045714///regulation of low-density lipoprotein particle receptor biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0042632///cholesterol homeostasis+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006886///intracellular protein transport","SEC24 homolog A, COPII coat complex component","[SC24A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24A {ECO:0000305}; AltName: Full=SEC24-related protein A;+++[B4E205_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61651, highly similar to Protein transport protein Sec24A {ECO:0000313|EMBL:BAG64967.1};+++[H0Y9J6_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24A {ECO:0000313|Ensembl:ENSP00000424273}; Flags: Fragment;"]
[10826,"'FAXDC2'",260.73,257.01,315,277.58,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0016491///oxidoreductase activity+++GO:0000254///C-4 methylsterol oxidase activity+++GO:0005506///iron ion binding","GO:0008610///lipid biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0016126///sterol biosynthetic process","fatty acid hydroxylase domain containing 2","[FXDC2_HUMAN|Reviewed]RecName: Full=Fatty acid hydroxylase domain-containing protein 2;+++[E5RFJ7_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000428834};+++[E5RH66_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429876};+++[E5RH84_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429837}; Flags: Fragment;+++[E5RIK6_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429406};+++[E5RJN8_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429004};+++[E5RJQ9_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000431084};+++[E5RK01_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000431015}; Flags: Fragment;+++[E5RK16_HUMAN|Unreviewed]SubName: Full=Fatty acid hydroxylase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000428992};+++[L8E882_HUMAN|Unreviewed]SubName: Full=Alternative protein C5orf4 {ECO:0000313|EMBL:CCQ42941.1};+++[Q9UHK3_HUMAN|Unreviewed]SubName: Full=Chromosome 5 open reading frame 4, isoform CRA_a {ECO:0000313|EMBL:EAW61629.1}; SubName: Full=Putative tumor suppressor {ECO:0000313|EMBL:AAF22611.1};"]
[10865,"'ARID5A'",474,584,486,514.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0030331///estrogen receptor binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0046966///thyroid hormone receptor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046965///retinoid X receptor binding+++GO:0003714///transcription corepressor activity+++GO:0003677///DNA binding+++GO:0050681///androgen receptor binding+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045087///innate immune response+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002376///immune system process+++GO:0071391///cellular response to estrogen stimulus","AT-rich interaction domain 5A","[ARI5A_HUMAN|Reviewed]RecName: Full=AT-rich interactive domain-containing protein 5A; Short=ARID domain-containing protein 5A; AltName: Full=Modulator recognition factor 1; Short=MRF-1;+++[F6Q9D3_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000397286};"]
[10886,"'NPFFR2'",0,3,0,1,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0015629///actin cytoskeleton+++GO:0005886///plasma membrane","GO:0008188///neuropeptide receptor activity+++GO:0031628///opioid receptor binding+++GO:0004930///G protein-coupled receptor activity","GO:0045761///regulation of adenylate cyclase activity+++GO:0009582///detection of abiotic stimulus+++GO:0043408///regulation of MAPK cascade+++GO:0007218///neuropeptide signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0032870///cellular response to hormone stimulus+++GO:2000479///regulation of cAMP-dependent protein kinase activity","neuropeptide FF receptor 2","[NPFF2_HUMAN|Reviewed]RecName: Full=Neuropeptide FF receptor 2; AltName: Full=G-protein coupled receptor 74; AltName: Full=G-protein coupled receptor HLWAR77; AltName: Full=Neuropeptide G-protein coupled receptor;+++[A0PJM9_HUMAN|Unreviewed]SubName: Full=Neuropeptide FF receptor 2 {ECO:0000313|EMBL:AAI13714.2}; SubName: Full=Neuropeptide FF receptor 2, isoform CRA_b {ECO:0000313|EMBL:EAX05648.1}; SubName: Full=cDNA FLJ75415, highly similar to Homo sapiens G protein-coupled receptor 74 (GPR74), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83626.1};"]
[10908,"'PNPLA6'",2069,2100,1946,2038.33333333333,"00564///Glycerophospholipid metabolism","H01898///PNPLA6-related disorders+++H00266///Hereditary spastic paraplegia (SPG)",null,"R02747///2-Acyl-sn-glycero-3-phosphocholine acylhydrolase   2-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid+++R03416///1-Acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase   1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine+++R03417///L-2-Lysophosphatidylethanolamine aldehydohydrolase   2-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine+++R02746///1-Acyl-sn-glycero-3-phosphocholine acylhydrolase   1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0016787///hydrolase activity+++GO:0004622///lysophospholipase activity","GO:0046475///glycerophospholipid catabolic process+++GO:0006629///lipid metabolic process+++GO:0046470///phosphatidylcholine metabolic process+++GO:0016042///lipid catabolic process","patatin like phospholipase domain containing 6","[PLPL6_HUMAN|Reviewed]RecName: Full=Neuropathy target esterase {ECO:0000303|PubMed:9576844}; EC=3.1.1.5; AltName: Full=Patatin-like phospholipase domain-containing protein 6 {ECO:0000305};+++[A0A0B4NEY1_HUMAN|Unreviewed]SubName: Full=Mutant PNPLA6 protein {ECO:0000313|EMBL:AIL88794.1}; Flags: Fragment;+++[A0A0B4NF33_HUMAN|Unreviewed]SubName: Full=Mutant PNPLA6 protein {ECO:0000313|EMBL:AIL88795.1}; Flags: Fragment;+++[A0A0B4NFD1_HUMAN|Unreviewed]SubName: Full=PNPLA6 protein {ECO:0000313|EMBL:AIL88797.1}; Flags: Fragment;+++[A0A0B4NFS2_HUMAN|Unreviewed]SubName: Full=Mutant PNPLA6 protein {ECO:0000313|EMBL:AIL88798.1}; Flags: Fragment;+++[A0A2R8Y7E1_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000496219}; Flags: Fragment;+++[M0QXH7_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000469171}; Flags: Fragment;+++[M0QYF5_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000469794}; Flags: Fragment;+++[M0QYT1_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000470060}; Flags: Fragment;+++[M0QZD1_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000470461}; Flags: Fragment;+++[M0QZK5_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000470608}; Flags: Fragment;+++[M0R2C2_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000472456}; Flags: Fragment;+++[M0R2H4_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000472572}; Flags: Fragment;+++[M0R2K2_HUMAN|Unreviewed]SubName: Full=Neuropathy target esterase {ECO:0000313|Ensembl:ENSP00000472631}; Flags: Fragment;"]
[10926,"'DBF4'",32,33,28,31,"04110///Cell cycle",{"$nulls":3},"GO:0031431///Dbf4-dependent protein kinase complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0046872///metal ion binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0003676///nucleic acid binding","GO:0000082///G1/S transition of mitotic cell cycle+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0043085///positive regulation of catalytic activity+++GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0045740///positive regulation of DNA replication","DBF4 zinc finger","[DBF4A_HUMAN|Reviewed]RecName: Full=Protein DBF4 homolog A; AltName: Full=Activator of S phase kinase; AltName: Full=Chiffon homolog A; AltName: Full=DBF4-type zinc finger-containing protein 1;+++[B4DXK0_HUMAN|Unreviewed]SubName: Full=Protein DBF4 homolog A {ECO:0000313|Ensembl:ENSP00000389397}; SubName: Full=cDNA FLJ59266, highly similar to Protein DBF4 homolog {ECO:0000313|EMBL:BAG63412.1};+++[B7Z8C6_HUMAN|Unreviewed]SubName: Full=DBF4 homolog (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW76931.1}; SubName: Full=cDNA FLJ61644, highly similar to Protein DBF4 homolog {ECO:0000313|EMBL:BAH13912.1};+++[F8WF77_HUMAN|Unreviewed]SubName: Full=Protein DBF4 homolog A {ECO:0000313|Ensembl:ENSP00000407116};"]
[10946,"'SF3A3'",931,976,824,910.333333333333,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding","GO:0000389///mRNA 3'-splice site recognition+++GO:0008380///RNA splicing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","splicing factor 3a subunit 3","[SF3A3_HUMAN|Reviewed]RecName: Full=Splicing factor 3A subunit 3; AltName: Full=SF3a60; AltName: Full=Spliceosome-associated protein 61; Short=SAP 61;+++[B4DW90_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58737, highly similar to Splicing factor 3A subunit 3 {ECO:0000313|EMBL:BAG62952.1};"]
[10969,"'EBNA1BP2'",795,869,818,827.333333333333,{"$nulls":4},"GO:0034399///nuclear periphery+++GO:0030687///preribosome, large subunit precursor+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0006364///rRNA processing+++GO:0042273///ribosomal large subunit biogenesis+++GO:0042254///ribosome biogenesis","EBNA1 binding protein 2","[EBP2_HUMAN|Reviewed]RecName: Full=Probable rRNA-processing protein EBP2; AltName: Full=EBNA1-binding protein 2; AltName: Full=Nucleolar protein p40;+++[H7C2Q8_HUMAN|Unreviewed]SubName: Full=EBNA1 binding protein 2, isoform CRA_d {ECO:0000313|EMBL:EAX07115.1}; SubName: Full=Probable rRNA-processing protein EBP2 {ECO:0000313|Ensembl:ENSP00000407323};+++[Q6IB29_HUMAN|Unreviewed]SubName: Full=EBNA1 binding protein 2 {ECO:0000313|EMBL:AAP35566.1}; SubName: Full=EBNA1 binding protein 2 variant {ECO:0000313|EMBL:BAD97175.1}; SubName: Full=EBNA1 binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAX07112.1}; SubName: Full=EBNA1BP2 protein {ECO:0000313|EMBL:CAG33256.1};"]
[10982,"'MAPRE2'",533,520,524,525.666666666667,null,"H01579///Congenital symmetric circumferential skin creases",null,null,"GO:0035371///microtubule plus-end+++GO:0005881///cytoplasmic microtubule+++GO:0042995///cell projection+++GO:0005875///microtubule associated complex+++GO:0032391///photoreceptor connecting cilium+++GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment+++GO:0005925///focal adhesion+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0051233///spindle midzone+++GO:0097542///ciliary tip+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005930///axoneme+++GO:0005856///cytoskeleton","GO:0020037///heme binding+++GO:0019901///protein kinase binding+++GO:0008017///microtubule binding+++GO:0051010///microtubule plus-end binding+++GO:0042802///identical protein binding+++GO:0004096///catalase activity+++GO:0005515///protein binding","GO:0043547///positive regulation of GTPase activity+++GO:0051301///cell division+++GO:0042461///photoreceptor cell development+++GO:0071482///cellular response to light stimulus+++GO:0035845///photoreceptor cell outer segment organization+++GO:1904825///protein localization to microtubule plus-end+++GO:0098869///cellular oxidant detoxification+++GO:0035372///protein localization to microtubule+++GO:0032014///positive regulation of ARF protein signal transduction+++GO:1903393///positive regulation of adherens junction organization+++GO:0007603///phototransduction, visible light+++GO:0046549///retinal cone cell development+++GO:0055114///oxidation-reduction process+++GO:0060041///retina development in camera-type eye+++GO:0045494///photoreceptor cell maintenance+++GO:0051225///spindle assembly+++GO:0007049///cell cycle+++GO:0050896///response to stimulus+++GO:0046548///retinal rod cell development+++GO:0035082///axoneme assembly+++GO:0007165///signal transduction+++GO:0008283///cell proliferation+++GO:0035556///intracellular signal transduction+++GO:0051549///positive regulation of keratinocyte migration+++GO:0031110///regulation of microtubule polymerization or depolymerization+++GO:0030030///cell projection organization+++GO:0060042///retina morphogenesis in camera-type eye+++GO:0007601///visual perception+++GO:1902857///positive regulation of non-motile cilium assembly","microtubule associated protein RP/EB family member 2","[MARE2_HUMAN|Reviewed]RecName: Full=Microtubule-associated protein RP/EB family member 2; AltName: Full=APC-binding protein EB2; AltName: Full=End-binding protein 2; Short=EB2;+++[A0A024RC33_HUMAN|Unreviewed]SubName: Full=Microtubule-associated protein, RP/EB family, member 2, isoform CRA_a {ECO:0000313|EMBL:EAX01339.1};+++[A0A1B0GTV9_HUMAN|Unreviewed]SubName: Full=Oxygen-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000489857};+++[A0A1B0GUH0_HUMAN|Unreviewed]SubName: Full=Oxygen-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000490104};+++[A0FDN2_HUMAN|Unreviewed]SubName: Full=Retinitis pigmentosa 1 {ECO:0000313|EMBL:ABJ97137.1}; Flags: Fragment;+++[K7EL66_HUMAN|Unreviewed]SubName: Full=Microtubule-associated protein RP/EB family member 2 {ECO:0000313|Ensembl:ENSP00000465939}; Flags: Fragment;+++[K7ENB3_HUMAN|Unreviewed]SubName: Full=Microtubule-associated protein RP/EB family member 2 {ECO:0000313|Ensembl:ENSP00000466871}; Flags: Fragment;+++[K7ERD8_HUMAN|Unreviewed]SubName: Full=Microtubule-associated protein RP/EB family member 2 {ECO:0000313|Ensembl:ENSP00000468216}; Flags: Fragment;+++[M0QX52_HUMAN|Unreviewed]SubName: Full=Microtubule-associated protein RP/EB family member 2 {ECO:0000313|Ensembl:ENSP00000468904}; Flags: Fragment;+++[Q6DKV0_HUMAN|Unreviewed]SubName: Full=Retinitis pigmentosa 1 {ECO:0000313|EMBL:AAT75005.1}; Flags: Fragment;"]
[10991,"'SLC38A3'",1733,1910,3121,2254.66666666667,"04727///GABAergic synapse+++04724///Glutamatergic synapse+++04964///Proximal tubule bicarbonate reclamation",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0004060///arylamine N-acetyltransferase activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0005290///L-histidine transmembrane transporter activity+++GO:0008080///N-acetyltransferase activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0016407///acetyltransferase activity+++GO:0015297///antiporter activity+++GO:0015182///L-asparagine transmembrane transporter activity","GO:0015808///L-alanine transport+++GO:0006867///asparagine transport+++GO:0006814///sodium ion transport+++GO:2000487///positive regulation of glutamine transport+++GO:0006865///amino acid transport+++GO:0006811///ion transport+++GO:0006805///xenobiotic metabolic process+++GO:0007420///brain development+++GO:0051365///cellular response to potassium ion starvation+++GO:0007565///female pregnancy+++GO:0015817///histidine transport+++GO:0089709///L-histidine transmembrane transport+++GO:0006868///glutamine transport+++GO:0061402///positive regulation of transcription from RNA polymerase II promoter in response to acidic pH+++GO:0003333///amino acid transmembrane transport","solute carrier family 38 member 3","[S38A3_HUMAN|Reviewed]RecName: Full=Sodium-coupled neutral amino acid transporter 3; AltName: Full=N-system amino acid transporter 1; AltName: Full=Na(+)-coupled neutral amino acid transporter 3; AltName: Full=Solute carrier family 38 member 3; AltName: Full=System N amino acid transporter 1;+++[A0A087WVW8_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 3 {ECO:0000313|Ensembl:ENSP00000479737}; Flags: Fragment;+++[A0A087WWS5_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 3 {ECO:0000313|Ensembl:ENSP00000480466}; Flags: Fragment;+++[A0A087X175_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 3 {ECO:0000313|Ensembl:ENSP00000483959};+++[A0A087X1Q4_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 3 {ECO:0000313|Ensembl:ENSP00000484379}; Flags: Fragment;+++[Q400I9_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltranserase 1 {ECO:0000313|EMBL:CAE46170.1}; EC=2.3.1.5 {ECO:0000313|EMBL:CAE46169.1, ECO:0000313|EMBL:CAE46170.1}; SubName: Full=Arylamine N-acetyltransferase {ECO:0000313|EMBL:CAE46169.1}; Flags: Fragment;+++[Q5C8V2_HUMAN|Unreviewed]SubName: Full=N-acetyltransferase-1 {ECO:0000313|EMBL:AAX22230.1}; Flags: Fragment;+++[Q6U7I7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 1 variant {ECO:0000313|EMBL:AAQ74989.1}; Flags: Fragment;+++[Q9HAQ5_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 1 {ECO:0000313|EMBL:AAG23842.1}; EC=2.3.1.5 {ECO:0000313|EMBL:AAG23842.1};"]
[11023,"'VAX1'",15,37,26,26,null,"H01027///Anophthalmia and microphthalmia (A/M)",null,null,"GO:0005634///nucleus","GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0031490///chromatin DNA binding","GO:0060021///roof of mouth development+++GO:0001764///neuron migration+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0043010///camera-type eye development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0007406///negative regulation of neuroblast proliferation+++GO:0030154///cell differentiation+++GO:0007417///central nervous system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0035914///skeletal muscle cell differentiation+++GO:0007275///multicellular organism development","ventral anterior homeobox 1","[VAX1_HUMAN|Reviewed]RecName: Full=Ventral anterior homeobox 1;"]
[11035,"'RIPK3'",1,0,1,0.666666666666667,"04668///TNF signaling pathway+++04217///Necroptosis+++04621///NOD-like receptor signaling pathway+++04623///Cytosolic DNA-sensing pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0004704///NF-kappaB-inducing kinase activity+++GO:0016301///kinase activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0003713///transcription coactivator activity","GO:2000377///regulation of reactive oxygen species metabolic process+++GO:0051291///protein heterooligomerization+++GO:0046006///regulation of activated T cell proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0032649///regulation of interferon-gamma production+++GO:1990000///amyloid fibril formation+++GO:0097190///apoptotic signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0006464///cellular protein modification process+++GO:0001914///regulation of T cell mediated cytotoxicity+++GO:0070266///necroptotic process+++GO:0032147///activation of protein kinase activity+++GO:2000452///regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation+++GO:0051260///protein homooligomerization+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0048538///thymus development+++GO:0012501///programmed cell death+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0060545///positive regulation of necroptotic process+++GO:0043029///T cell homeostasis+++GO:0048535///lymph node development+++GO:0010940///positive regulation of necrotic cell death+++GO:0016310///phosphorylation+++GO:0048536///spleen development+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0010922///positive regulation of phosphatase activity+++GO:0033077///T cell differentiation in thymus+++GO:0070235///regulation of activation-induced cell death of T cells+++GO:0051351///positive regulation of ligase activity+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0038061///NIK/NF-kappaB signaling+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0002819///regulation of adaptive immune response","receptor interacting serine/threonine kinase 3","[RIPK3_HUMAN|Reviewed]RecName: Full=Receptor-interacting serine/threonine-protein kinase 3; EC=2.7.11.1; AltName: Full=RIP-like protein kinase 3; AltName: Full=Receptor-interacting protein 3; Short=RIP-3;+++[H0YJN5_HUMAN|Unreviewed]SubName: Full=Receptor-interacting serine/threonine-protein kinase 3 {ECO:0000313|Ensembl:ENSP00000451840}; Flags: Fragment;"]
[11061,"'CNMD'",29,13,42,28,{"$nulls":4},"GO:0005576///extracellular region+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:0001501///skeletal system development+++GO:0006029///proteoglycan metabolic process+++GO:0007275///multicellular organism development+++GO:0051216///cartilage development+++GO:0030154///cell differentiation+++GO:0016525///negative regulation of angiogenesis","chondromodulin","[CNMD_HUMAN|Reviewed]RecName: Full=Leukocyte cell-derived chemotaxin 1 {ECO:0000305}; AltName: Full=Chondromodulin {ECO:0000312|HGNC:HGNC:17005}; Contains: RecName: Full=Chondrosurfactant protein; Short=CH-SP; Contains: RecName: Full=Chondromodulin-1; AltName: Full=Chondromodulin-I; Short=ChM-I; Flags: Precursor;+++[E9PKI9_HUMAN|Unreviewed]SubName: Full=Leukocyte cell-derived chemotaxin 1 {ECO:0000313|Ensembl:ENSP00000396035}; Flags: Fragment;"]
[1107,"'CHD3'",3380,3135,3118,3211,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0016581///NuRD complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0004407///histone deacetylase activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding","GO:0007051///spindle organization+++GO:0006333///chromatin assembly or disassembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007098///centrosome cycle+++GO:0006325///chromatin organization+++GO:0032508///DNA duplex unwinding+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016575///histone deacetylation","chromodomain helicase DNA binding protein 3","[CHD3_HUMAN|Reviewed]RecName: Full=Chromodomain-helicase-DNA-binding protein 3; Short=CHD-3; EC=3.6.4.12; AltName: Full=ATP-dependent helicase CHD3; AltName: Full=Mi-2 autoantigen 240 kDa protein; AltName: Full=Mi2-alpha; AltName: Full=Zinc finger helicase; Short=hZFH;+++[B3KWV4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43940 fis, clone TESTI4014175, highly similar to Chromodomain helicase-DNA-binding protein 3 {ECO:0000313|EMBL:BAG54266.1};+++[H7C0J3_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000395252}; Flags: Fragment;+++[H7C2H0_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000405861}; Flags: Fragment;+++[H7C3H7_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000411959}; Flags: Fragment;+++[I3L1I4_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000458861}; Flags: Fragment;+++[I3L229_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000459321}; Flags: Fragment;+++[K7EPV1_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000467547}; Flags: Fragment;+++[Q2TAZ1_HUMAN|Unreviewed]SubName: Full=CHD3 protein {ECO:0000313|EMBL:AAI10649.1}; Flags: Fragment;"]
[11100,"'HNRNPUL1'",5935.37,6170.85,6009,6038.40666666667,"05164///Influenza A",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0009615///response to virus+++GO:0006396///RNA processing","heterogeneous nuclear ribonucleoprotein U like 1","[HNRL1_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1; AltName: Full=Adenovirus early region 1B-associated protein 5; AltName: Full=E1B-55 kDa-associated protein 5; Short=E1B-AP5;+++[A0A024R0J9_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW57027.1};+++[A0A087X1I2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000484226};+++[A0A0A0MRA5_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000340857};+++[A8K3W4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75163, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein U-like 1 (HNRPUL1), transcript variant 4, mRNA {ECO:0000313|EMBL:BAF83418.1};+++[B7Z4B8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56481, highly similar to Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|EMBL:BAH12504.1};+++[L0R5B4_HUMAN|Unreviewed]SubName: Full=Alternative protein HNRNPUL1 {ECO:0000313|EMBL:CCO13744.1};+++[M0QYG9_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000469816}; Flags: Fragment;+++[M0QYI8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000469858}; Flags: Fragment;+++[M0QYM5_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000469934}; Flags: Fragment;+++[M0QYZ0_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000470172}; Flags: Fragment;+++[M0QZV6_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000470793}; Flags: Fragment;+++[M0R0K8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000471302}; Flags: Fragment;+++[M0R203_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000472221}; Flags: Fragment;+++[M0R247_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000472315};+++[M0R3F1_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like protein 1 {ECO:0000313|Ensembl:ENSP00000473178}; Flags: Fragment;+++[Q9BTB7_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein U-like 1 {ECO:0000313|EMBL:AAH04242.1};"]
[11112,"'HIBADH'",659,604,800,687.666666666667,"01100///Metabolic pathways+++00280///Valine, leucine and isoleucine degradation",null,null,"R05066///3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase   (S)-3-Hydroxyisobutyrate + NAD+ <=> (S)-Methylmalonate semialdehyde + NADH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016491///oxidoreductase activity+++GO:0051287///NAD binding+++GO:0008442///3-hydroxyisobutyrate dehydrogenase activity+++GO:0050661///NADP binding","GO:0006574///valine catabolic process+++GO:0009083///branched-chain amino acid catabolic process+++GO:0055114///oxidation-reduction process","3-hydroxyisobutyrate dehydrogenase","[3HIDH_HUMAN|Reviewed]RecName: Full=3-hydroxyisobutyrate dehydrogenase, mitochondrial; Short=HIBADH; EC=1.1.1.31; Flags: Precursor;+++[A0A024RA75_HUMAN|Unreviewed]RecName: Full=3-hydroxyisobutyrate dehydrogenase {ECO:0000256|RuleBase:RU910714}; Short=HIBADH {ECO:0000256|RuleBase:RU910714}; EC=1.1.1.31 {ECO:0000256|RuleBase:RU910714};+++[F8WET2_HUMAN|Unreviewed]SubName: Full=3-hydroxyisobutyrate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000393365};+++[H7BZL2_HUMAN|Unreviewed]SubName: Full=3-hydroxyisobutyrate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000390205}; Flags: Fragment;"]
[11138,"'TBC1D8'",58,56,86,66.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005623///cell","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0008015///blood circulation+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity+++GO:1902017///regulation of cilium assembly+++GO:0008284///positive regulation of cell proliferation","TBC1 domain family member 8","[TBCD8_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 8; AltName: Full=AD 3; AltName: Full=Vascular Rab-GAP/TBC-containing protein;+++[J3KQ40_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 8 {ECO:0000313|Ensembl:ENSP00000386856};"]
[11149,"'BVES'",188,122,245.99,185.33,"04530///Tight junction","H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005923///bicellular tight junction+++GO:0030054///cell junction+++GO:0031253///cell projection membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0016328///lateral plasma membrane+++GO:0005886///plasma membrane","GO:0005198///structural molecule activity+++GO:0030552///cAMP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0042391///regulation of membrane potential+++GO:0007519///skeletal muscle tissue development+++GO:0048278///vesicle docking+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0060931///sinoatrial node cell development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:2001135///regulation of endocytic recycling+++GO:0040017///positive regulation of locomotion+++GO:0001921///positive regulation of receptor recycling+++GO:0043087///regulation of GTPase activity+++GO:0002027///regulation of heart rate+++GO:0008360///regulation of cell shape+++GO:0060973///cell migration involved in heart development+++GO:0007507///heart development+++GO:0090136///epithelial cell-cell adhesion+++GO:0016192///vesicle-mediated transport+++GO:0002931///response to ischemia+++GO:0007517///muscle organ development","blood vessel epicardial substance","[POPD1_HUMAN|Reviewed]RecName: Full=Blood vessel epicardial substance {ECO:0000312|HGNC:HGNC:1152}; Short=hBVES; AltName: Full=Popeye domain-containing protein 1; Short=Popeye protein 1;"]
[1117,"'CHI3L2'",0,0,4,1.33333333333333,null,"H01649///Schizophrenia",null,null,"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0008061///chitin binding+++GO:0030246///carbohydrate binding+++GO:0004568///chitinase activity+++GO:0016787///hydrolase activity","GO:0005975///carbohydrate metabolic process","chitinase 3 like 2","[CH3L2_HUMAN|Reviewed]RecName: Full=Chitinase-3-like protein 2; AltName: Full=Chondrocyte protein 39; AltName: Full=YKL-39; Flags: Precursor;+++[E9PII8_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000431978}; Flags: Fragment;+++[E9PIX1_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000431968}; Flags: Fragment;+++[E9PP75_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000436380}; Flags: Fragment;+++[E9PPX4_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000436272}; Flags: Fragment;+++[E9PR52_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000436077}; Flags: Fragment;+++[E9PRL9_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000436006}; Flags: Fragment;+++[H0YD88_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000433176}; Flags: Fragment;+++[H0YE91_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000435250}; Flags: Fragment;+++[H0YEJ1_HUMAN|Unreviewed]SubName: Full=Chitinase-3-like protein 2 {ECO:0000313|Ensembl:ENSP00000435935}; Flags: Fragment;"]
[11184,"'MAP4K1'",31,45,52,42.6666666666667,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005622///intracellular","GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0008349///MAP kinase kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0008283///cell proliferation+++GO:0046777///protein autophosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade+++GO:0023014///signal transduction by protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:0000185///activation of MAPKKK activity+++GO:0016310///phosphorylation+++GO:0007257///activation of JUN kinase activity","mitogen-activated protein kinase kinase kinase kinase 1","[M4K1_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase kinase 1; EC=2.7.11.1; AltName: Full=Hematopoietic progenitor kinase; AltName: Full=MAPK/ERK kinase kinase kinase 1; Short=MEK kinase kinase 1; Short=MEKKK 1;+++[K7EJS6_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase kinase 1 {ECO:0000313|Ensembl:ENSP00000465303}; Flags: Fragment;+++[K7EKT6_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase kinase 1 {ECO:0000313|Ensembl:ENSP00000465774};+++[K7ER95_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase kinase {ECO:0000256|PIRNR:PIRNR038172}; EC=2.7.11.1 {ECO:0000256|PIRNR:PIRNR038172};+++[K7ERT2_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase kinase 1 {ECO:0000313|Ensembl:ENSP00000468396}; Flags: Fragment;"]
[11213,"'IRAK3'",0,1,3,1.33333333333333,"04722///Neurotrophin signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0046982///protein heterodimerization activity","GO:0032494///response to peptidoglycan+++GO:0019221///cytokine-mediated signaling pathway+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0045824///negative regulation of innate immune response+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0010933///positive regulation of macrophage tolerance induction+++GO:0032496///response to lipopolysaccharide+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0043244///regulation of protein complex disassembly+++GO:0035556///intracellular signal transduction+++GO:0043330///response to exogenous dsRNA+++GO:0009615///response to virus+++GO:0032695///negative regulation of interleukin-12 production+++GO:0043242///negative regulation of protein complex disassembly+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0042177///negative regulation of protein catabolic process+++GO:0006468///protein phosphorylation+++GO:0010936///negative regulation of macrophage cytokine production+++GO:0070555///response to interleukin-1+++GO:0032715///negative regulation of interleukin-6 production","interleukin 1 receptor associated kinase 3","[IRAK3_HUMAN|Reviewed]RecName: Full=Interleukin-1 receptor-associated kinase 3; Short=IRAK-3; EC=2.7.11.1; AltName: Full=IL-1 receptor-associated kinase M; Short=IRAK-M;+++[F5GYN6_HUMAN|Unreviewed]SubName: Full=Interleukin-1 receptor-associated kinase 3 {ECO:0000313|Ensembl:ENSP00000441321};"]
[112267857,"'LOC112267857'",2,7,5,4.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","uncharacterized LOC112267857","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF1_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein {ECO:0000305}; Short=L1-ORF1p {ECO:0000303|PubMed:28806172}; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1; AltName: Full=Transposase element L1Md-A101/L1Md-A102/L1Md-A2;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[112268068,"'LOC112268068'",2,1,3,2,{"$nulls":7},"uncharacterized LOC112268068","[BAG1_HUMAN|diamond]RecName: Full=BAG family molecular chaperone regulator 1; Short=BAG-1; AltName: Full=Bcl-2-associated athanogene 1;"]
[112268271,"'LOC112268271'",4,1,1,2,{"$nulls":4},"GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0035686///sperm fibrous sheath+++GO:0005737///cytoplasm","GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding+++GO:0004364///glutathione transferase activity","GO:0070458///cellular detoxification of nitrogen compound+++GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0043627///response to estrogen+++GO:0006749///glutathione metabolic process","translation initiation factor IF-2-like","[GSTM3_HUMAN|diamond]RecName: Full=Glutathione S-transferase Mu 3; EC=2.5.1.18; AltName: Full=GST class-mu 3; AltName: Full=GSTM3-3; Short=hGSTM3-3;+++[GSTM3_MACFU|diamond]RecName: Full=Glutathione S-transferase Mu 3; EC=2.5.1.18; AltName: Full=GST class-mu 3; AltName: Full=GSTM3-3;+++[GSTM5_MOUSE|diamond]RecName: Full=Glutathione S-transferase Mu 5; EC=2.5.1.18; AltName: Full=Fibrous sheath component 2; Short=Fsc2; AltName: Full=GST class-mu 5;+++[GSTM5_RAT|diamond]RecName: Full=Glutathione S-transferase Mu 5; EC=2.5.1.18; AltName: Full=GST class-mu 5;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;"]
[112268321,"'LOC112268321'",86,97,80,87.6666666666667,"01100///Metabolic pathways+++00270///Cysteine and methionine metabolism",null,"M00034///Methionine salvage pathway","R07363///1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming) 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 3-(Methylthio)propanoate + Formate + CO+++R07364///1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming) 1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one + Oxygen <=> 4-Methylthio-2-oxobutanoic acid + Formate","GO:0030008///TRAPP complex+++GO:0005886///plasma membrane+++GO:0000776///kinetochore+++GO:0005829///cytosol+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0010309///acireductone dioxygenase [iron(II)-requiring] activity+++GO:0016491///oxidoreductase activity+++GO:0004175///endopeptidase activity+++GO:0005506///iron ion binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:1905342///positive regulation of protein localization to kinetochore+++GO:0090234///regulation of kinetochore assembly+++GO:0051259///protein complex oligomerization+++GO:0051310///metaphase plate congression+++GO:0019509///L-methionine salvage from methylthioadenosine","uncharacterized LOC112268321","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[MTND_BOVIN|diamond]RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154};+++[MTND_HUMAN|diamond]RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Submergence-induced protein-like factor; Short=Sip-L;+++[MTND_MACMU|diamond]RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154};+++[MTND_MONDO|diamond]RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154};+++[MTND_RAT|diamond]RecName: Full=1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; EC=1.13.11.54 {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Short=ARD {ECO:0000255|HAMAP-Rule:MF_03154}; Short=Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; AltName: Full=Androgen-responsive ARD-like protein 1; AltName: Full=Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; Short=MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154};+++[TPC12_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 12 {ECO:0000305}; AltName: Full=Tetratricopeptide repeat protein 15 {ECO:0000303|PubMed:21525244}; Short=TPR repeat protein 15 {ECO:0000303|PubMed:21525244}; Short=TTC-15 {ECO:0000303|PubMed:21525244}; AltName: Full=Trafficking of membranes and mitosis {ECO:0000303|PubMed:25918224};+++[TPC12_MOUSE|diamond]RecName: Full=Trafficking protein particle complex subunit 12 {ECO:0000305}; AltName: Full=Tetratricopeptide repeat protein 15 {ECO:0000250|UniProtKB:Q8WVT3}; Short=TPR repeat protein 15 {ECO:0000250|UniProtKB:Q8WVT3};+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[112268453,"'112268453'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0000794///condensed nuclear chromosome+++GO:0016605///PML body+++GO:0015629///actin cytoskeleton+++GO:0001673///male germ cell nucleus","GO:0042802///identical protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation",null,"[A0A2K5TTP1_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000003425};+++[A0A2K6B637_MACNE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000006873};"]
[11243,"'PMF1'",517.18,578.09,532.86,542.71,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000777///condensed chromosome kinetochore+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000818///nuclear MIS12/MIND complex+++GO:0005829///cytosol+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0000444///MIS12/MIND type complex+++GO:0005794///Golgi apparatus","GO:0043522///leucine zipper domain binding+++GO:0003713///transcription coactivator activity","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0006366///transcription by RNA polymerase II+++GO:0007059///chromosome segregation+++GO:0006355///regulation of transcription, DNA-templated","polyamine modulated factor 1","[PMF1_HUMAN|Reviewed]RecName: Full=Polyamine-modulated factor 1; Short=PMF-1;"]
[11255,"'HRH3'",1,0,0,0.333333333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0098793///presynapse+++GO:0016021///integral component of membrane","GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0004969///histamine receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0014050///negative regulation of glutamate secretion+++GO:0001505///regulation of neurotransmitter levels+++GO:0014063///negative regulation of serotonin secretion+++GO:0007269///neurotransmitter secretion+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0014061///regulation of norepinephrine secretion+++GO:0050890///cognition","histamine receptor H3","[HRH3_HUMAN|Reviewed]RecName: Full=Histamine H3 receptor; Short=H3R; Short=HH3R; AltName: Full=G-protein coupled receptor 97;+++[A0A087WZD3_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor {ECO:0000313|Ensembl:ENSP00000482567};+++[A0A0A0MR48_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor {ECO:0000313|Ensembl:ENSP00000321482}; SubName: Full=Histamine receptor H3, isoform CRA_b {ECO:0000313|EMBL:EAW75382.1};+++[Q548M6_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 1 {ECO:0000313|EMBL:AAL71911.1};+++[Q8NI49_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 6 {ECO:0000313|EMBL:AAM43829.1};+++[Q8NI50_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 5 {ECO:0000313|EMBL:AAM43828.1};+++[Q8WXZ9_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 4 {ECO:0000313|EMBL:AAL71914.1};+++[Q8WY00_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 3 {ECO:0000313|EMBL:AAL71913.1};+++[Q8WY01_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 2 {ECO:0000313|EMBL:AAL71912.1};"]
[112724,"'RDH13'",475,410,467,450.666666666667,{"$nulls":4},"GO:0005743///mitochondrial inner membrane","GO:0016491///oxidoreductase activity+++GO:0052650///NADP-retinol dehydrogenase activity","GO:0009644///response to high light intensity+++GO:0055114///oxidation-reduction process+++GO:0010842///retina layer formation+++GO:0042572///retinol metabolic process+++GO:0042462///eye photoreceptor cell development","retinol dehydrogenase 13","[RDH13_HUMAN|Reviewed]RecName: Full=Retinol dehydrogenase 13; EC=1.1.1.-; AltName: Full=Short chain dehydrogenase/reductase family 7C member 3;+++[A0A024R4M8_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 (All-trans and 9-cis), isoform CRA_a {ECO:0000313|EMBL:EAW72322.1};+++[B3KVA3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16300 fis, clone PLACE7000167, highly similar to Retinol dehydrogenase 13 {ECO:0000313|EMBL:BAG53715.1};+++[G8JLA1_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000291892};+++[K7EMY5_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000466708}; Flags: Fragment;+++[K7EQB5_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000467754}; Flags: Fragment;+++[K7ERV1_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000468422};"]
[112817,"'HOGA1'",90,94.98,144.27,109.75,"01100///Metabolic pathways+++00330///Arginine and proline metabolism+++00630///Glyoxylate and dicarboxylate metabolism",null,null,"R00471///4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)   (4R)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate+++R00470///4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)   4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate","GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0005759///mitochondrial matrix","GO:0003824///catalytic activity+++GO:0016829///lyase activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0008700///4-hydroxy-2-oxoglutarate aldolase activity","GO:0019470///4-hydroxyproline catabolic process+++GO:0042866///pyruvate biosynthetic process+++GO:0033609///oxalate metabolic process+++GO:0009436///glyoxylate catabolic process+++GO:0046487///glyoxylate metabolic process","4-hydroxy-2-oxoglutarate aldolase 1","[HOGA1_HUMAN|Reviewed]RecName: Full=4-hydroxy-2-oxoglutarate aldolase, mitochondrial; EC=4.1.3.16; AltName: Full=Dihydrodipicolinate synthase-like; Short=DHDPS-like protein; AltName: Full=Probable 2-keto-4-hydroxyglutarate aldolase; Short=Probable KHG-aldolase; AltName: Full=Protein 569272; Flags: Precursor;+++[H7BY76_HUMAN|Unreviewed]SubName: Full=4-hydroxy-2-oxoglutarate aldolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000359676}; Flags: Fragment;"]
[113000,"'RPUSD1'",494,548,528,523.333333333333,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0003723///RNA binding+++GO:0009982///pseudouridine synthase activity","GO:0001522///pseudouridine synthesis+++GO:0008150///biological_process+++GO:0009451///RNA modification","RNA pseudouridylate synthase domain containing 1","[RUSD1_HUMAN|Reviewed]RecName: Full=RNA pseudouridylate synthase domain-containing protein 1; AltName: Full=Ribosomal large subunit pseudouridine synthase C-like protein;+++[H3BMZ6_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000454616}; Flags: Fragment;+++[H3BQN8_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW85714.1}; SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000455862};+++[H3BRG3_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000456231}; Flags: Fragment;+++[H3BS55_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000456545};+++[H3BSG4_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000456692}; Flags: Fragment;+++[H3BU91_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000457527};+++[H3BUN6_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000457722};+++[H3BVD0_HUMAN|Unreviewed]SubName: Full=RNA pseudouridylate synthase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000458059}; Flags: Fragment;+++[Q96E34_HUMAN|Unreviewed]SubName: Full=RPUSD1 protein {ECO:0000313|EMBL:AAH12951.2}; Flags: Fragment;"]
[113179,"'ADAT3'",54,62,74,63.3333333333333,null,"H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0003824///catalytic activity","GO:0008033///tRNA processing","adenosine deaminase, tRNA specific 3","[ADAT3_HUMAN|Reviewed]RecName: Full=Probable inactive tRNA-specific adenosine deaminase-like protein 3; AltName: Full=tRNA-specific adenosine-34 deaminase subunit ADAT3;+++[C9JFC1_HUMAN|Unreviewed]SubName: Full=Probable inactive tRNA-specific adenosine deaminase-like protein 3 {ECO:0000313|Ensembl:ENSP00000404502}; Flags: Fragment;+++[D6W601_HUMAN|Unreviewed]SubName: Full=HCG22695, isoform CRA_a {ECO:0000313|EMBL:EAW69436.1}; SubName: Full=Probable inactive tRNA-specific adenosine deaminase-like protein 3 {ECO:0000313|Ensembl:ENSP00000332448};+++[Q7Z2S3_HUMAN|Unreviewed]SubName: Full=FWP005 {ECO:0000313|EMBL:AAQ13496.1}; SubName: Full=MSTP121 {ECO:0000313|EMBL:AAQ13643.1};"]
[11329,"'STK38'",1784,1315,1280,1459.66666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0045296///cadherin binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0006464///cellular protein modification process+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043407///negative regulation of MAP kinase activity","serine/threonine kinase 38","[STK38_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 38; EC=2.7.11.1; AltName: Full=NDR1 protein kinase; AltName: Full=Nuclear Dbf2-related kinase 1;+++[A0A024RD18_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};"]
[1134,"'CHRNA1'",19,13,19,17,"04080///Neuroactive ligand-receptor interaction","H00986///Multiple pterygium syndrome+++H00770///Congenital myasthenic syndrome",null,null,"GO:0005887///integral component of plasma membrane+++GO:0043005///neuron projection+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0031594///neuromuscular junction+++GO:0045211///postsynaptic membrane+++GO:0030054///cell junction+++GO:0005892///acetylcholine-gated channel complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0045202///synapse","GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential+++GO:0015464///acetylcholine receptor activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0042166///acetylcholine binding+++GO:0005216///ion channel activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity","GO:0050905///neuromuscular process+++GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0048630///skeletal muscle tissue growth+++GO:0003009///skeletal muscle contraction+++GO:0006812///cation transport+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0070050///neuron cellular homeostasis+++GO:0042391///regulation of membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0007528///neuromuscular junction development+++GO:0007274///neuromuscular synaptic transmission+++GO:0050881///musculoskeletal movement+++GO:0007268///chemical synaptic transmission+++GO:0050877///nervous system process+++GO:0007271///synaptic transmission, cholinergic+++GO:0019228///neuronal action potential+++GO:0046716///muscle cell cellular homeostasis+++GO:0007165///signal transduction+++GO:0035094///response to nicotine","cholinergic receptor nicotinic alpha 1 subunit","[ACHA_HUMAN|Reviewed]RecName: Full=Acetylcholine receptor subunit alpha; Flags: Precursor;+++[A0A1B0GV17_HUMAN|Unreviewed]SubName: Full=Acetylcholine receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000490338};+++[B8ZZD3_HUMAN|Unreviewed]SubName: Full=Acetylcholine receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000387026};+++[E7ENE5_HUMAN|Unreviewed]SubName: Full=Acetylcholine receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000386611};+++[F8WDS3_HUMAN|Unreviewed]SubName: Full=Acetylcholine receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000395805};+++[G5E9G9_HUMAN|Unreviewed]SubName: Full=Acetylcholine receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000386684}; SubName: Full=Cholinergic receptor, nicotinic, alpha 1 (Muscle), isoform CRA_c {ECO:0000313|EMBL:EAX11126.1};+++[Q53SH4_HUMAN|Unreviewed]SubName: Full=Cholinergic receptor, nicotinic, alpha 1 (Muscle), isoform CRA_a {ECO:0000313|EMBL:EAX11124.1}; SubName: Full=cDNA FLJ77888, highly similar to Human muscle acetylcholine receptor alpha-subunit {ECO:0000313|EMBL:BAF84027.1}; SubName: Full=cDNA, FLJ96344, Homo sapiens cholinergic receptor, nicotinic, alpha polypeptide 1(muscle) (CHRNA1), mRNA {ECO:0000313|EMBL:BAG37716.1};"]
[113675,"'SDSL'",121,157,121,133,"01200///Carbon metabolism+++01130///Biosynthesis of antibiotics+++00260///Glycine, serine and threonine metabolism+++00270///Cysteine and methionine metabolism+++01110///Biosynthesis of secondary metabolites+++00290///Valine, leucine and isoleucine biosynthesis+++01100///Metabolic pathways+++01230///Biosynthesis of amino acids",null,"M00570///Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine","R00996///L-threonine ammonia-lyase (2-oxobutanoate-forming)   L-Threonine <=> 2-Oxobutanoate + Ammonia+++R00590///L-serine hydro-lyase   L-Serine <=> Dehydroalanine + H2O+++R00220///L-serine ammonia-lyase   L-Serine <=> Pyruvate + Ammonia","GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005829///cytosol","GO:0003674///molecular_function+++GO:0016829///lyase activity+++GO:0003941///L-serine ammonia-lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0042802///identical protein binding+++GO:0004794///L-threonine ammonia-lyase activity+++GO:0003824///catalytic activity+++GO:0016836///hydro-lyase activity+++GO:0050662///coenzyme binding","GO:0006565///L-serine catabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0019518///L-threonine catabolic process to glycine+++GO:0006567///threonine catabolic process+++GO:0008150///biological_process","serine dehydratase like","[SDSL_HUMAN|Reviewed]RecName: Full=Serine dehydratase-like; AltName: Full=L-serine deaminase; AltName: Full=L-serine dehydratase/L-threonine deaminase; AltName: Full=L-threonine dehydratase; Short=TDH; EC=4.3.1.19; AltName: Full=Serine dehydratase 2; Short=SDH 2; EC=4.3.1.17;+++[A0A024RBL2_HUMAN|Unreviewed]SubName: Full=Serine dehydratase-like, isoform CRA_a {ECO:0000313|EMBL:EAW98058.1};+++[F8VYZ3_HUMAN|Unreviewed]SubName: Full=Serine dehydratase-like {ECO:0000313|Ensembl:ENSP00000448868}; Flags: Fragment;+++[F8VZ97_HUMAN|Unreviewed]SubName: Full=Serine dehydratase-like {ECO:0000313|Ensembl:ENSP00000446867}; Flags: Fragment;+++[H0YIA2_HUMAN|Unreviewed]SubName: Full=Serine dehydratase-like {ECO:0000313|Ensembl:ENSP00000448950}; Flags: Fragment;+++[H0YID3_HUMAN|Unreviewed]SubName: Full=Serine dehydratase-like {ECO:0000313|Ensembl:ENSP00000449136}; Flags: Fragment;"]
[114,"'ADCY8'",8,14,7,9.66666666666667,"04926///Relaxin signaling pathway+++04918///Thyroid hormone synthesis+++04725///Cholinergic synapse+++04923///Regulation of lipolysis in adipocytes+++04971///Gastric acid secretion+++04540///Gap junction+++04928///Parathyroid hormone synthesis, secretion and action+++04915///Estrogen signaling pathway+++04970///Salivary secretion+++04213///Longevity regulating pathway - multiple species+++04022///cGMP-PKG signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04934///Cushing's syndrome+++05414///Dilated cardiomyopathy (DCM)+++04912///GnRH signaling pathway+++04727///GABAergic synapse+++04072///Phospholipase D signaling pathway+++04925///Aldosterone synthesis and secretion+++04024///cAMP signaling pathway+++04270///Vascular smooth muscle contraction+++04913///Ovarian steroidogenesis+++05200///Pathways in cancer+++04261///Adrenergic signaling in cardiomyocytes+++04742///Taste transduction+++05163///Human cytomegalovirus infection+++04927///Cortisol synthesis and secretion+++04020///Calcium signaling pathway+++04723///Retrograde endocannabinoid signaling+++04921///Oxytocin signaling pathway+++04916///Melanogenesis+++04976///Bile secretion+++04611///Platelet activation+++04211///Longevity regulating pathway+++04371///Apelin signaling pathway+++04015///Rap1 signaling pathway+++05032///Morphine addiction+++00230///Purine metabolism+++04720///Long-term potentiation+++04114///Oocyte meiosis+++04062///Chemokine signaling pathway+++04724///Glutamatergic synapse+++04911///Insulin secretion+++01522///Endocrine resistance+++05166///HTLV-I infection+++04713///Circadian entrainment+++04972///Pancreatic secretion+++04714///Thermogenesis+++04914///Progesterone-mediated oocyte maturation",null,"M00695///cAMP signaling","R00089///ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming)   ATP <=> 3',5'-Cyclic AMP + Diphosphate+++R00434///GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)   GTP <=> 3',5'-Cyclic GMP + Diphosphate","GO:0005929///cilium+++GO:0005887///integral component of plasma membrane+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005901///caveola+++GO:0005905///clathrin-coated pit+++GO:0032809///neuronal cell body membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0060076///excitatory synapse+++GO:0016323///basolateral plasma membrane+++GO:0014069///postsynaptic density+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0030424///axon+++GO:0015629///actin cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0045121///membrane raft+++GO:0048786///presynaptic active zone+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0030425///dendrite+++GO:0016020///membrane+++GO:0044853///plasma membrane raft","GO:0046983///protein dimerization activity+++GO:0004016///adenylate cyclase activity+++GO:0051721///protein phosphatase 2A binding+++GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0000166///nucleotide binding+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0005516///calmodulin binding+++GO:0003779///actin binding","GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007613///memory+++GO:0035556///intracellular signal transduction+++GO:1904322///cellular response to forskolin+++GO:0150076///neuroinflammatory response+++GO:0008355///olfactory learning+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0003091///renal water homeostasis+++GO:0051260///protein homooligomerization+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0010255///glucose mediated signaling pathway+++GO:0034199///activation of protein kinase A activity+++GO:0080135///regulation of cellular response to stress+++GO:0042593///glucose homeostasis+++GO:0071315///cellular response to morphine+++GO:0030317///flagellated sperm motility+++GO:0051259///protein complex oligomerization+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0007611///learning or memory+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:0007626///locomotory behavior+++GO:0007616///long-term memory+++GO:0007340///acrosome reaction+++GO:0007338///single fertilization+++GO:0050896///response to stimulus+++GO:0071277///cellular response to calcium ion+++GO:0007165///signal transduction+++GO:0071377///cellular response to glucagon stimulus+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0031915///positive regulation of synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0006171///cAMP biosynthetic process+++GO:0038003///opioid receptor signaling pathway+++GO:0071333///cellular response to glucose stimulus+++GO:0007608///sensory perception of smell","adenylate cyclase 8","[ADCY8_HUMAN|Reviewed]RecName: Full=Adenylate cyclase type 8; EC=4.6.1.1; AltName: Full=ATP pyrophosphate-lyase 8; AltName: Full=Adenylate cyclase type VIII {ECO:0000303|PubMed:8076676}; AltName: Full=Adenylyl cyclase 8; Short=AC8; AltName: Full=Ca(2+)/calmodulin-activated adenylyl cyclase;+++[A0A0K0K1K3_HUMAN|Unreviewed]RecName: Full=Adenylate cyclase {ECO:0000256|PIRNR:PIRNR039050}; EC=4.6.1.1 {ECO:0000256|PIRNR:PIRNR039050};+++[C9J969_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000406153}; Flags: Fragment;+++[C9JLX3_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000389799}; Flags: Fragment;+++[C9JYB5_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000401455}; Flags: Fragment;+++[E5RFR2_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 8 {ECO:0000313|Ensembl:ENSP00000428010}; Flags: Fragment;+++[E7EVL1_HUMAN|Unreviewed]RecName: Full=Adenylate cyclase {ECO:0000256|PIRNR:PIRNR039050}; EC=4.6.1.1 {ECO:0000256|PIRNR:PIRNR039050};+++[H7C1A6_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000399275}; Flags: Fragment;+++[H7C1S5_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000402008}; Flags: Fragment;+++[L8E7I7_HUMAN|Unreviewed]SubName: Full=Alternative protein ADCY8 {ECO:0000313|EMBL:CCQ43094.1};+++[Q4F7X0_HUMAN|Unreviewed]RecName: Full=Adenylate cyclase {ECO:0000256|PIRNR:PIRNR039050}; EC=4.6.1.1 {ECO:0000256|PIRNR:PIRNR039050};+++[U3KQ91_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000475652}; Flags: Fragment;+++[U3KQR1_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000476143}; Flags: Fragment;"]
[1147,"'CHUK'",212,180,248,213.333333333333,"04658///Th1 and Th2 cell differentiation+++04064///NF-kappa B signaling pathway+++05168///Herpes simplex infection+++05200///Pathways in cancer+++05418///Fluid shear stress and atherosclerosis+++04151///PI3K-Akt signaling pathway+++04662///B cell receptor signaling pathway+++01523///Antifolate resistance+++04668///TNF signaling pathway+++05215///Prostate cancer+++04621///NOD-like receptor signaling pathway+++05145///Toxoplasmosis+++04657///IL-17 signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05222///Small cell lung cancer+++04920///Adipocytokine signaling pathway+++04659///Th17 cell differentiation+++05220///Chronic myeloid leukemia+++04625///C-type lectin receptor signaling pathway+++05169///Epstein-Barr virus infection+++05166///HTLV-I infection+++04150///mTOR signaling pathway+++05163///Human cytomegalovirus infection+++05160///Hepatitis C+++04010///MAPK signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++04068///FoxO signaling pathway+++05161///Hepatitis B+++04014///Ras signaling pathway+++04623///Cytosolic DNA-sensing pathway+++05162///Measles+++05142///Chagas disease (American trypanosomiasis)+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04660///T cell receptor signaling pathway+++05131///Shigellosis+++05221///Acute myeloid leukemia+++04062///Chemokine signaling pathway+++05165///Human papillomavirus infection+++04210///Apoptosis+++05212///Pancreatic cancer","H00882///Cocoon syndrome","M00686///Toll-like receptor signaling",null,"GO:0008385///IkappaB kinase complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0035631///CD40 receptor complex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0046982///protein heterodimerization activity+++GO:0016301///kinase activity+++GO:0097110///scaffold protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0008384///IkappaB kinase activity+++GO:0000166///nucleotide binding+++GO:0042803///protein homodimerization activity","GO:0003009///skeletal muscle contraction+++GO:1902741///positive regulation of interferon-alpha secretion+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0009615///response to virus+++GO:0002756///MyD88-independent toll-like receptor signaling pathway+++GO:0098586///cellular response to virus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0006468///protein phosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0033194///response to hydroperoxide+++GO:0009636///response to toxic substance+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0009653///anatomical structure morphogenesis+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0071356///cellular response to tumor necrosis factor+++GO:0010034///response to acetate+++GO:0051146///striated muscle cell differentiation+++GO:0045087///innate immune response+++GO:0050852///T cell receptor signaling pathway+++GO:0007252///I-kappaB phosphorylation+++GO:0006954///inflammatory response+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0051403///stress-activated MAPK cascade+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043200///response to amino acid+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0006955///immune response+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0042493///response to drug+++GO:0010033///response to organic substance+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0038061///NIK/NF-kappaB signaling+++GO:0034614///cellular response to reactive oxygen species+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032496///response to lipopolysaccharide+++GO:0016310///phosphorylation+++GO:0071276///cellular response to cadmium ion","conserved helix-loop-helix ubiquitous kinase","[IKKA_HUMAN|Reviewed]RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; EC=2.7.11.10; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA; AltName: Full=Transcription factor 16; Short=TCF-16;+++[Q562E6_HUMAN|Unreviewed]SubName: Full=Conserved helix-loop-helix ubiquitous kinase {ECO:0000313|EMBL:AAH92514.1};"]
[114789,"'SLC25A25'",148,150,149,149,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0022857///transmembrane transporter activity+++GO:0005347///ATP transmembrane transporter activity+++GO:0046872///metal ion binding","GO:0046034///ATP metabolic process+++GO:0060612///adipose tissue development+++GO:0070588///calcium ion transmembrane transport+++GO:0002021///response to dietary excess+++GO:0055085///transmembrane transport+++GO:0035264///multicellular organism growth+++GO:0032094///response to food+++GO:0045333///cellular respiration+++GO:0043010///camera-type eye development+++GO:0015867///ATP transport+++GO:0014823///response to activity","solute carrier family 25 member 25","[SCMC2_HUMAN|Reviewed]RecName: Full=Calcium-binding mitochondrial carrier protein SCaMC-2; AltName: Full=Mitochondrial ATP-Mg/Pi carrier protein 3; AltName: Full=Mitochondrial Ca(2+)-dependent solute carrier protein 3; AltName: Full=Small calcium-binding mitochondrial carrier protein 2; AltName: Full=Solute carrier family 25 member 25;+++[F8WEY9_HUMAN|Unreviewed]SubName: Full=Calcium-binding mitochondrial carrier protein SCaMC-2 {ECO:0000313|Ensembl:ENSP00000419685};+++[H7C4Z4_HUMAN|Unreviewed]SubName: Full=Calcium-binding mitochondrial carrier protein SCaMC-2 {ECO:0000313|Ensembl:ENSP00000418600}; Flags: Fragment;+++[L0R8F1_HUMAN|Unreviewed]SubName: Full=Alternative protein SLC25A25 {ECO:0000313|EMBL:CCO13816.1};"]
[114879,"'OSBPL5'",264,259,221,248,"04979///Cholesterol metabolism",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0032934///sterol binding+++GO:0008289///lipid binding+++GO:0001786///phosphatidylserine binding+++GO:0015485///cholesterol binding+++GO:0005548///phospholipid transporter activity+++GO:0015248///sterol transporter activity+++GO:0008142///oxysterol binding","GO:0030301///cholesterol transport+++GO:0006869///lipid transport+++GO:0006893///Golgi to plasma membrane transport+++GO:0015914///phospholipid transport+++GO:0008203///cholesterol metabolic process+++GO:0036150///phosphatidylserine acyl-chain remodeling","oxysterol binding protein like 5","[OSBL5_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 5; Short=ORP-5; Short=OSBP-related protein 5; AltName: Full=Oxysterol-binding protein homolog 1 {ECO:0000303|PubMed:12504849};+++[A8KAD5_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[E9PIJ6_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000435812}; Flags: Fragment;+++[E9PJE6_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000433754}; Flags: Fragment;+++[E9PLN3_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000433222}; Flags: Fragment;+++[E9PNH0_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000437141};+++[E9PPQ2_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000436950}; Flags: Fragment;+++[E9PQB4_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000432507}; Flags: Fragment;+++[E9PRA9_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000434265};+++[H0YCD7_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;"]
[114899,"'C1QTNF3'",4,8,5,5.66666666666667,"00040///Pentose and glucuronate interconversions+++04146///Peroxisome+++01110///Biosynthesis of secondary metabolites+++00860///Porphyrin and chlorophyll metabolism+++04142///Lysosome+++04137///Mitophagy - animal+++00531///Glycosaminoglycan degradation+++00944///Flavone and flavonol biosynthesis+++04140///Autophagy - animal+++00983///Drug metabolism - other enzymes+++00120///Primary bile acid biosynthesis+++01100///Metabolic pathways","H02099///Alpha-methylacyl-CoA racemase deficiency+++H00132///Mucopolysaccharidosis type VII (MPS7)+++H00421///Mucopolysaccharidosis (MPS)+++H00407///Peroxisomal beta-oxidation enzyme deficiency+++H00628///Congenital bile acid synthesis defect (CBAS)","M00014///Glucuronate pathway (uronate pathway)+++M00077///Chondroitin sulfate degradation+++M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate+++M00076///Dermatan sulfate degradation+++M00129///Ascorbate biosynthesis, animals, glucose-1P => ascorbate+++M00078///Heparan sulfate degradation","R07818///G13040 + H2O <=> G09660 + D-Glucuronate+++R08739///3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA 25-epimerase (25R)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA <=> (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R08127///beta-D-glucuronoside glucuronosohydrolase Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + H2O <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + D-Glucuronate+++R10830///beta-D-glucuronoside glucuronosohydrolase G00526 + H2O <=> G00711 + D-Glucuronate+++R08260///SN38 glucuronide glucuronosohydrolase SN38 glucuronide + H2O <=> SN-38 + D-Glucuronate+++R08734///3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA 25-epimerase (25R)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA <=> (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA+++R04979///Bilirubin beta-diglucuronide glucuronosohydrolase Bilirubin beta-diglucuronide + 2 H2O + 3 Reduced acceptor <=> D-Urobilinogen + 2 D-Glucuronate + 3 Acceptor+++R01478///beta-D-glucuronoside glucuronosohydrolase H2O + beta-D-Glucuronoside <=> D-Glucuronate + Alcohol","GO:0070062///extracellular exosome+++GO:0005581///collagen trimer+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005623///cell","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0070206///protein trimerization+++GO:1900165///negative regulation of interleukin-6 secretion+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0050728///negative regulation of inflammatory response+++GO:0010629///negative regulation of gene expression+++GO:0050715///positive regulation of cytokine secretion+++GO:0035356///cellular triglyceride homeostasis+++GO:0045721///negative regulation of gluconeogenesis+++GO:0070165///positive regulation of adiponectin secretion+++GO:0045444///fat cell differentiation+++GO:0071638///negative regulation of monocyte chemotactic protein-1 production","C1q and TNF related 3","[C1QT3_HUMAN|Reviewed]RecName: Full=Complement C1q tumor necrosis factor-related protein 3; AltName: Full=Collagenous repeat-containing sequence 26 kDa protein; Short=CORS26; AltName: Full=Secretory protein CORS26; Flags: Precursor;"]
[115123,"'MARCH3'",19,13,18,16.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030659///cytoplasmic vesicle membrane+++GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0005768///endosome","GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0016567///protein ubiquitination+++GO:0006897///endocytosis","membrane associated ring-CH-type finger 3","[MARH3_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MARCH3; EC=2.3.2.27; AltName: Full=Membrane-associated RING finger protein 3; AltName: Full=Membrane-associated RING-CH protein III; Short=MARCH-III; AltName: Full=RING finger protein 173; AltName: Full=RING-type E3 ubiquitin transferase MARCH3 {ECO:0000305};"]
[115286,"'SLC25A26'",163,168,165,165.333333333333,null,"H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion","GO:0000095///S-adenosyl-L-methionine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006811///ion transport+++GO:0015805///S-adenosyl-L-methionine transport+++GO:1901962///S-adenosyl-L-methionine transmembrane transport","solute carrier family 25 member 26","[SAMC_HUMAN|Reviewed]RecName: Full=S-adenosylmethionine mitochondrial carrier protein; AltName: Full=Mitochondrial S-adenosylmethionine transporter; AltName: Full=Solute carrier family 25 member 26;+++[H0YCZ5_HUMAN|Unreviewed]SubName: Full=S-adenosylmethionine mitochondrial carrier protein {ECO:0000313|Ensembl:ENSP00000432574};+++[H0YF50_HUMAN|Unreviewed]SubName: Full=S-adenosylmethionine mitochondrial carrier protein {ECO:0000313|Ensembl:ENSP00000437217}; Flags: Fragment;+++[H7C430_HUMAN|Unreviewed]SubName: Full=S-adenosylmethionine mitochondrial carrier protein {ECO:0000313|Ensembl:ENSP00000415304};"]
[1154,"'CISH'",9,8,6,7.66666666666667,"04630///Jak-STAT signaling pathway+++04917///Prolactin signaling pathway",null,"M00684///JAK-STAT signaling+++M00388///ECS complex",null,"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005575///cellular_component+++GO:0005942///phosphatidylinositol 3-kinase complex","GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity","GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0001558///regulation of cell growth+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0016567///protein ubiquitination+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0040008///regulation of growth+++GO:0009968///negative regulation of signal transduction+++GO:0035556///intracellular signal transduction+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0043687///post-translational protein modification+++GO:0038111///interleukin-7-mediated signaling pathway","cytokine inducible SH2 containing protein","[CISH_HUMAN|Reviewed]RecName: Full=Cytokine-inducible SH2-containing protein; Short=CIS; AltName: Full=CIS-1; AltName: Full=Protein G18; AltName: Full=Suppressor of cytokine signaling; Short=SOCS;"]
[115825,"'WDFY2'",68,63,95,75.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0031982///vesicle+++GO:0005768///endosome","GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0001934///positive regulation of protein phosphorylation+++GO:0045600///positive regulation of fat cell differentiation","WD repeat and FYVE domain containing 2","[WDFY2_HUMAN|Reviewed]RecName: Full=WD repeat and FYVE domain-containing protein 2; AltName: Full=Propeller-FYVE protein {ECO:0000303|PubMed:16792529}; Short=Prof; AltName: Full=WD40- and FYVE domain-containing protein 2; AltName: Full=Zinc finger FYVE domain-containing protein 22;+++[A0A087WZX3_HUMAN|Unreviewed]SubName: Full=WD repeat and FYVE domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000482942};"]
[116039,"'OSR2'",3,2,1,2,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030501///positive regulation of bone mineralization+++GO:0060021///roof of mouth development+++GO:0001823///mesonephros development+++GO:0061029///eyelid development in camera-type eye+++GO:0033687///osteoblast proliferation+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0042733///embryonic digit morphogenesis+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0001656///metanephros development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0042474///middle ear morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0035115///embryonic forelimb morphogenesis+++GO:0060322///head development+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0002062///chondrocyte differentiation+++GO:0072498///embryonic skeletal joint development+++GO:0042476///odontogenesis+++GO:0060349///bone morphogenesis+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0001655///urogenital system development","odd-skipped related transciption factor 2","[OSR2_HUMAN|Reviewed]RecName: Full=Protein odd-skipped-related 2;+++[E5RGY8_HUMAN|Unreviewed]SubName: Full=Protein odd-skipped-related 2 {ECO:0000313|Ensembl:ENSP00000430074}; Flags: Fragment;+++[E5RH04_HUMAN|Unreviewed]SubName: Full=Protein odd-skipped-related 2 {ECO:0000313|Ensembl:ENSP00000430041};+++[E5RH47_HUMAN|Unreviewed]SubName: Full=Protein odd-skipped-related 2 {ECO:0000313|Ensembl:ENSP00000429910}; Flags: Fragment;"]
[116328,"'C8orf34'",6,4,3,4.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0010494///cytoplasmic stress granule","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003727///single-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding","GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition","chromosome 8 open reading frame 34","[CH034_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C8orf34; AltName: Full=Protein VEST-1;+++[A0A2P0CTR9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C8orf34 {ECO:0000313|Ensembl:ENSP00000429102};+++[E5RJD9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C8orf34 {ECO:0000313|Ensembl:ENSP00000429081};"]
[116461,"'TSEN15'",122,123,154,133,null,"H00897///Pontocerebellar hypoplasia",null,null,"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0004519///endonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0000213///tRNA-intron endonuclease activity","GO:0006397///mRNA processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0008033///tRNA processing+++GO:0090501///RNA phosphodiester bond hydrolysis","tRNA splicing endonuclease subunit 15","[SEN15_HUMAN|Reviewed]RecName: Full=tRNA-splicing endonuclease subunit Sen15; AltName: Full=SEN15 homolog; Short=HsSEN15; AltName: Full=tRNA-intron endonuclease Sen15;+++[A0A2R8Y5L0_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000494533};+++[A0A2R8Y5Q6_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000494978}; Flags: Fragment;+++[A0A2R8Y5W5_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000495107}; Flags: Fragment;+++[A0A2R8Y6A4_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000495178};+++[A0A2R8Y6B3_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000495409}; Flags: Fragment;+++[A0A2R8Y6M5_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000495344};+++[A0A2R8Y7T8_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000496242};+++[A0A2R8YDU8_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000494932};+++[A0A2R8YEM0_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000494455};+++[A0A2R8YG40_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000495621};+++[A0A2R8YHG0_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000496688}; Flags: Fragment;+++[A0A2U3TZM3_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 19, isoform CRA_a {ECO:0000313|EMBL:EAW91173.1}; SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000355299};+++[B1ALV0_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 19, isoform CRA_c {ECO:0000313|EMBL:EAW91175.1}; SubName: Full=cDNA FLJ40877 fis, clone UMVEN2000354, highly similar to tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|EMBL:BAG53590.1};+++[E9PPN1_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000436996};+++[F2Z3M0_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000435144};+++[H0YCV5_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen15 {ECO:0000313|Ensembl:ENSP00000432397}; Flags: Fragment;"]
[116986,"'AGAP2'",6,11,14,10.3333333333333,"04144///Endocytosis+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane","GO:0019901///protein kinase binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0046872///metal ion binding+++GO:0005096///GTPase activator activity+++GO:0030295///protein kinase activator activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0061903///positive regulation of 1-phosphatidylinositol-3-kinase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0015031///protein transport+++GO:0042177///negative regulation of protein catabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0032147///activation of protein kinase activity+++GO:0060749///mammary gland alveolus development+++GO:0045944///positive regulation of transcription by RNA polymerase II","ArfGAP with GTPase domain, ankyrin repeat and PH domain 2","[AGAP2_HUMAN|Reviewed]RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; Short=AGAP-2; AltName: Full=Centaurin-gamma-1; Short=Cnt-g1; AltName: Full=GTP-binding and GTPase-activating protein 2; Short=GGAP2; AltName: Full=Phosphatidylinositol 3-kinase enhancer; Short=PIKE;+++[A0A024RB55_HUMAN|Unreviewed]SubName: Full=Centaurin, gamma 1, isoform CRA_b {ECO:0000313|EMBL:EAW97051.1};+++[F8VVT9_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000449241};+++[H0YHB1_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000446683}; Flags: Fragment;+++[J3KNM6_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000328160}; Flags: Fragment;"]
[117248,"'GALNT15'",16.1,20,26,20.7,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0030133///transport vesicle+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0030246///carbohydrate binding+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity","GO:0016266///O-glycan processing","polypeptide N-acetylgalactosaminyltransferase 15","[GLT15_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 15; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase-like protein 2; Short=GalNAc-T-like protein 2; Short=pp-GaNTase-like protein 2; AltName: Full=Polypeptide N-acetylgalactosaminyltransferase-like protein 2; AltName: Full=Protein-UDP acetylgalactosaminyltransferase-like protein 2; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 2;+++[A0A1L4BJ91_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx2-7 {ECO:0000313|EMBL:API81387.1};+++[A0A1L4BJA6_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[A0A1L4BJA8_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[A0A1L4BJA9_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[A0A1L4BJB0_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx8 {ECO:0000313|EMBL:API81391.1};+++[A0A1L4BJB1_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 variant deltaEx6 delta39bpEx9 {ECO:0000313|EMBL:API81393.1};+++[A0A1L4BJC0_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[B3KT16_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[C9JGI4_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[C9JLI4_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 {ECO:0000313|Ensembl:ENSP00000414403}; Flags: Fragment;+++[E9PBY3_HUMAN|Unreviewed]SubName: Full=N-acetylgalactosaminyltransferase 7 {ECO:0000313|Ensembl:ENSP00000427050};+++[H0YAH3_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; Flags: Fragment;+++[H0YAK0_HUMAN|Unreviewed]SubName: Full=N-acetylgalactosaminyltransferase 7 {ECO:0000313|Ensembl:ENSP00000427341}; Flags: Fragment;+++[H7BZG2_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 {ECO:0000313|Ensembl:ENSP00000389447}; Flags: Fragment;+++[H7BZU4_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 {ECO:0000313|Ensembl:ENSP00000391469}; Flags: Fragment;+++[H7C0T6_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 {ECO:0000313|Ensembl:ENSP00000396612}; Flags: Fragment;+++[H7C2I5_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 {ECO:0000313|Ensembl:ENSP00000406237}; Flags: Fragment;+++[L8ECM1_HUMAN|Unreviewed]SubName: Full=Alternative protein GALNT13 {ECO:0000313|EMBL:CCQ43807.1};+++[Q4G146_HUMAN|Unreviewed]SubName: Full=GALNTL2 protein {ECO:0000313|EMBL:AAH30625.1}; SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 15 {ECO:0000313|Ensembl:ENSP00000480229};+++[Q4W5F7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein GALNT7 {ECO:0000313|EMBL:AAY41020.1}; Flags: Fragment;+++[Q68VJ0_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 13 {ECO:0000313|EMBL:CAD44542.1}; Flags: Fragment;+++[Q68VJ4_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 7 {ECO:0000313|EMBL:CAD44538.1}; Flags: Fragment;+++[Q96KE1_HUMAN|Unreviewed]SubName: Full=Pregnancy-induced hypertension syndrome-related protein 5 {ECO:0000313|EMBL:AAK48940.1}; Flags: Fragment;+++[X5DRI3_HUMAN|Unreviewed]SubName: Full=UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 isoform B {ECO:0000313|EMBL:AHW56697.1};"]
[1182,"'CLCN3'",1341,1025,1164,1176.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02147///X-linked recessive nephrolithiasis with renal failure+++H00694///Dent disease+++H00480///Non-syndromic X-linked mental retardation+++H00214///Hypophosphatemic rickets+++H02148///Low molecular weight proteinuria with hypercalciuria and nephrocalcinosis+++H02149///X-linked hypercalciuric nephrolithiasis+++H02142///X-linked recessive hypophosphatemic rickets",null,null,"GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0030141///secretory granule+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0045335///phagocytic vesicle+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0031901///early endosome membrane+++GO:0009897///external side of plasma membrane+++GO:0012506///vesicle membrane+++GO:0031902///late endosome membrane+++GO:0005770///late endosome+++GO:0030658///transport vesicle membrane+++GO:0005769///early endosome+++GO:0098982///GABA-ergic synapse+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0042581///specific granule+++GO:0016020///membrane+++GO:0008021///synaptic vesicle","GO:0005254///chloride channel activity+++GO:0042803///protein homodimerization activity+++GO:0031404///chloride ion binding+++GO:0030165///PDZ domain binding+++GO:0015297///antiporter activity+++GO:0015299///solute:proton antiporter activity+++GO:0005247///voltage-gated chloride channel activity+++GO:0005515///protein binding+++GO:0072320///volume-sensitive chloride channel activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0046982///protein heterodimerization activity","GO:0048388///endosomal lumen acidification+++GO:0097401///synaptic vesicle lumen acidification+++GO:1902476///chloride transmembrane transport+++GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:0006885///regulation of pH+++GO:0045794///negative regulation of cell volume+++GO:0006821///chloride transport","chloride voltage-gated channel 3","[CLCN3_HUMAN|Reviewed]RecName: Full=H(+)/Cl(-) exchange transporter 3; AltName: Full=Chloride channel protein 3; Short=ClC-3; AltName: Full=Chloride transporter ClC-3;+++[A0A087WU31_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};+++[A0A0A0MTB7_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};+++[B3KXK0_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221}; Flags: Fragment;+++[D6RDZ6_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 3 {ECO:0000313|Ensembl:ENSP00000425160}; Flags: Fragment;+++[D6RIX3_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 3 {ECO:0000313|Ensembl:ENSP00000425823}; Flags: Fragment;+++[E9PE15_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221}; Flags: Fragment;+++[H0Y8Z8_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 3 {ECO:0000313|Ensembl:ENSP00000422678}; Flags: Fragment;+++[Q7Z4M4_HUMAN|Unreviewed]SubName: Full=CLCN3 protein {ECO:0000313|EMBL:AAH54877.1}; Flags: Fragment;"]
[118663,"'BTBD16'",1,2,1,1.33333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0000151///ubiquitin ligase complex",null,null,"BTB domain containing 16","[BTBDG_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein 16;"]
[119032,"'BORCS7'",127.01,101,129.01,119.006666666667,{"$nulls":4},"GO:0005764///lysosome+++GO:0016020///membrane+++GO:0099078///BORC complex+++GO:0005765///lysosomal membrane","GO:0005515///protein binding",null,"BLOC-1 related complex subunit 7","[BORC7_HUMAN|Reviewed]RecName: Full=BLOC-1-related complex subunit 7 {ECO:0000305}; AltName: Full=Diaskedin {ECO:0000303|PubMed:25898167};+++[A0A0B4J1R7_HUMAN|Unreviewed]SubName: Full=BORCS7-ASMT readthrough (NMD candidate) {ECO:0000313|Ensembl:ENSP00000299353};"]
[12,"'SERPINA3'",4050,3625,5270,4315,null,"H01163///Corticosteroid-binding globulin (CBG) deficiency",null,null,"GO:0035578///azurophil granule lumen+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005622///intracellular+++GO:0034774///secretory granule lumen+++GO:0072562///blood microparticle+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0031093///platelet alpha granule lumen+++GO:0005634///nucleus","GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006954///inflammatory response+++GO:0006953///acute-phase response+++GO:0043312///neutrophil degranulation+++GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0019216///regulation of lipid metabolic process+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0002576///platelet degranulation","serpin family A member 3","[AACT_HUMAN|Reviewed]RecName: Full=Alpha-1-antichymotrypsin; Short=ACT; AltName: Full=Cell growth-inhibiting gene 24/25 protein; AltName: Full=Serpin A3; Contains: RecName: Full=Alpha-1-antichymotrypsin His-Pro-less; Flags: Precursor;+++[A0A024R6P0_HUMAN|Unreviewed]SubName: Full=Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 3, isoform CRA_c {ECO:0000313|EMBL:EAW81590.1};+++[A0A087WY93_HUMAN|Unreviewed]SubName: Full=Alpha-1-antichymotrypsin {ECO:0000313|Ensembl:ENSP00000481617}; Flags: Fragment;+++[G3V3A0_HUMAN|Unreviewed]SubName: Full=Alpha-1-antichymotrypsin {ECO:0000313|Ensembl:ENSP00000451119}; SubName: Full=Serpin peptidase inhibitor, clade A (Alpha-1 antiproteinase, antitrypsin), member 3, isoform CRA_a {ECO:0000313|EMBL:EAW81587.1};+++[G3V595_HUMAN|Unreviewed]SubName: Full=Alpha-1-antichymotrypsin {ECO:0000313|Ensembl:ENSP00000452246}; Flags: Fragment;"]
[1207,"'CLNS1A'",764,685,691,713.333333333333,"03013///RNA transport",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0034709///methylosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0034715///pICln-Sm protein complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0000387///spliceosomal snRNP assembly+++GO:0006884///cell volume homeostasis+++GO:0006821///chloride transport","chloride nucleotide-sensitive channel 1A","[ICLN_HUMAN|Reviewed]RecName: Full=Methylosome subunit pICln; AltName: Full=Chloride channel, nucleotide sensitive 1A; AltName: Full=Chloride conductance regulatory protein ICln; Short=I(Cln); AltName: Full=Chloride ion current inducer protein; Short=ClCI; AltName: Full=Reticulocyte pICln;+++[E9PJF4_HUMAN|Unreviewed]SubName: Full=Methylosome subunit pICln {ECO:0000313|Ensembl:ENSP00000433741};+++[E9PMI6_HUMAN|Unreviewed]SubName: Full=Methylosome subunit pICln {ECO:0000313|Ensembl:ENSP00000434963};+++[E9PQ83_HUMAN|Unreviewed]SubName: Full=Methylosome subunit pICln {ECO:0000313|Ensembl:ENSP00000432570};+++[H0YEN9_HUMAN|Unreviewed]SubName: Full=Methylosome subunit pICln {ECO:0000313|Ensembl:ENSP00000436245}; Flags: Fragment;+++[J3KN38_HUMAN|Unreviewed]SubName: Full=Methylosome subunit pICln {ECO:0000313|Ensembl:ENSP00000263309};+++[U3KPU0_HUMAN|Unreviewed]SubName: Full=Methylosome subunit pICln {ECO:0000313|Ensembl:ENSP00000475218}; Flags: Fragment;"]
[121340,"'SP7'",0,0,1,0.333333333333333,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding","GO:0001649///osteoblast differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060218///hematopoietic stem cell differentiation+++GO:2000738///positive regulation of stem cell differentiation","Sp7 transcription factor","[SP7_HUMAN|Reviewed]RecName: Full=Transcription factor Sp7; AltName: Full=Zinc finger protein osterix;+++[A0A024RAY8_HUMAN|Unreviewed]SubName: Full=Sp7 transcription factor, isoform CRA_a {ECO:0000313|EMBL:EAW96696.1};+++[F8VV67_HUMAN|Unreviewed]SubName: Full=Transcription factor Sp7 {ECO:0000313|Ensembl:ENSP00000449355}; Flags: Fragment;"]
[122525,"'C14orf28'",40,44,27,37,{"$nulls":7},"chromosome 14 open reading frame 28","[CN028_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C14orf28; AltName: Full=Dopamine receptor-interacting protein 1;+++[G3V4G8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C14orf28 {ECO:0000313|Ensembl:ENSP00000451791};"]
[122970,"'ACOT4'",32,25,38,31.6666666666667,"01110///Biosynthesis of secondary metabolites+++01040///Biosynthesis of unsaturated fatty acids+++01100///Metabolic pathways+++00062///Fatty acid elongation",null,null,"R08177///Linoleoyl-CoA hydrolase   Linoleoyl-CoA + H2O <=> CoA + Linoleate+++R08174///stearoyl-CoA hydrolase   Stearoyl-CoA + H2O <=> CoA + Octadecanoic acid+++R08182///8,11,14-Eicosatrienoyl-CoA + H2O <=> CoA + (8Z,11Z,14Z)-Icosatrienoic acid+++R08178///(9Z,12Z,15Z)-Octadecatrienoyl-CoA + H2O <=> CoA + (9Z,12Z,15Z)-Octadecatrienoic acid+++R01274///palmitoyl-CoA hydrolase   Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid+++R08183///Arachidonyl-CoA + H2O <=> CoA + Arachidonate+++R08179///(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA + H2O <=> CoA + (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid+++R09450///long-chain fatty-acyl-CoA hydrolase   Long-chain acyl-CoA + H2O <=> Long-chain fatty acid + CoA+++R08175///Icosanoyl-CoA hydrolase   Eicosanoyl-CoA + H2O <=> CoA + Icosanoic acid+++R08181///gamma-Linolenoyl-CoA + H2O <=> CoA + (6Z,9Z,12Z)-Octadecatrienoic acid+++R08176///oleoyl-CoA hydrolase   Oleoyl-CoA + H2O <=> CoA + (9Z)-Octadecenoic acid+++R08180///(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + H2O <=> CoA + (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid","GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix","GO:0047617///acyl-CoA hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0005102///signaling receptor binding+++GO:0004778///succinyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0016787///hydrolase activity","GO:0006631///fatty acid metabolic process+++GO:0032788///saturated monocarboxylic acid metabolic process+++GO:0043648///dicarboxylic acid metabolic process+++GO:0006625///protein targeting to peroxisome+++GO:0046459///short-chain fatty acid metabolic process+++GO:0019605///butyrate metabolic process+++GO:0000038///very long-chain fatty acid metabolic process+++GO:0043649///dicarboxylic acid catabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0006104///succinyl-CoA metabolic process+++GO:0032789///unsaturated monocarboxylic acid metabolic process","acyl-CoA thioesterase 4","[ACOT4_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A thioesterase 4; Short=Acyl-CoA thioesterase 4; EC=3.1.2.2 {ECO:0000269|PubMed:16940157}; AltName: Full=PTE-2b; AltName: Full=Peroxisomal acyl coenzyme A thioester hydrolase Ib; AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase Ib; Short=PTE-Ib;"]
[123036,"'TC2N'",93,70,118,93.6666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005575///cellular_component","GO:0003674///molecular_function",null,"tandem C2 domains, nuclear","[TAC2N_HUMAN|Reviewed]RecName: Full=Tandem C2 domains nuclear protein; AltName: Full=Membrane targeting tandem C2 domain-containing protein 1; AltName: Full=Tandem C2 protein in nucleus; Short=Tac2-N;+++[H0YJ73_HUMAN|Unreviewed]SubName: Full=Tandem C2 domains nuclear protein {ECO:0000313|Ensembl:ENSP00000450922}; Flags: Fragment;"]
[124045,"'SPATA33'",116,126,112,118,"04217///Necroptosis+++04144///Endocytosis","H00897///Pontocerebellar hypoplasia","M00412///ESCRT-III complex",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity","GO:1901673///regulation of mitotic spindle assembly+++GO:0016458///gene silencing+++GO:0006351///transcription, DNA-templated+++GO:0007076///mitotic chromosome condensation+++GO:0007034///vacuolar transport+++GO:0016192///vesicle-mediated transport+++GO:0010824///regulation of centrosome duplication+++GO:0007080///mitotic metaphase plate congression+++GO:0015031///protein transport+++GO:0006997///nucleus organization+++GO:0000920///septum digestion after cytokinesis+++GO:0045786///negative regulation of cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated","spermatogenesis associated 33","[SPT33_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 33;+++[A0A087WYH0_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 33 {ECO:0000313|Ensembl:ENSP00000481797};+++[H3BQG0_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 33 {ECO:0000313|Ensembl:ENSP00000455761}; Flags: Fragment;+++[H3BSG8_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 33 {ECO:0000313|Ensembl:ENSP00000456696}; Flags: Fragment;+++[J3KRC8_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 33 {ECO:0000313|Ensembl:ENSP00000461933}; Flags: Fragment;+++[J3KS00_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 33 {ECO:0000313|Ensembl:ENSP00000462233}; Flags: Fragment;+++[J3KS58_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 33 {ECO:0000313|Ensembl:ENSP00000462319};+++[J3KSB2_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 33 {ECO:0000313|Ensembl:ENSP00000462403}; Flags: Fragment;+++[Q86XC3_HUMAN|Unreviewed]SubName: Full=C16orf55 protein {ECO:0000313|EMBL:AAH45670.1}; Flags: Fragment;"]
[124152,"'IQCK'",260,325,326,303.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005829///cytosol+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005615///extracellular space","GO:0019901///protein kinase binding+++GO:0001664///G protein-coupled receptor binding+++GO:0004930///G protein-coupled receptor activity+++GO:0030295///protein kinase activator activity+++GO:0042803///protein homodimerization activity","GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0050729///positive regulation of inflammatory response+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0045666///positive regulation of neuron differentiation","IQ motif containing K","[IQCK_HUMAN|Reviewed]RecName: Full=IQ domain-containing protein K;+++[B4DXE1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50424 {ECO:0000313|EMBL:BAG63353.1};+++[B4E1V3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52048 {ECO:0000313|EMBL:BAG64915.1};+++[H3BPX0_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein K {ECO:0000313|Ensembl:ENSP00000455504}; Flags: Fragment;+++[H3BRX5_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein K {ECO:0000313|Ensembl:ENSP00000456448};+++[H3BU74_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein K {ECO:0000313|Ensembl:ENSP00000457506}; Flags: Fragment;+++[H3BV97_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein K {ECO:0000313|Ensembl:ENSP00000458010}; Flags: Fragment;+++[I3L193_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein K {ECO:0000313|Ensembl:ENSP00000458669};+++[Q96FR4_HUMAN|Unreviewed]SubName: Full=IQCK protein {ECO:0000313|EMBL:AAH10515.1}; Flags: Fragment;"]
[124923,"'SGK494'",27,17,15,19.6666666666667,{"$nulls":5},"GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation","uncharacterized serine/threonine-protein kinase SgK494","[SG494_HUMAN|Reviewed]RecName: Full=Uncharacterized serine/threonine-protein kinase SgK494; EC=2.7.11.1; AltName: Full=Sugen kinase 494;+++[E9PPC7_HUMAN|Unreviewed]SubName: Full=Uncharacterized serine/threonine-protein kinase SgK494 {ECO:0000313|Ensembl:ENSP00000434603}; Flags: Fragment;+++[J3QQT5_HUMAN|Unreviewed]SubName: Full=Uncharacterized serine/threonine-protein kinase SgK494 {ECO:0000313|Ensembl:ENSP00000463890}; Flags: Fragment;+++[J3QR23_HUMAN|Unreviewed]SubName: Full=Uncharacterized serine/threonine-protein kinase SgK494 {ECO:0000313|Ensembl:ENSP00000464010}; Flags: Fragment;+++[K7ERW7_HUMAN|Unreviewed]SubName: Full=Uncharacterized serine/threonine-protein kinase SgK494 {ECO:0000313|Ensembl:ENSP00000468448}; Flags: Fragment;"]
[124944,"'C17orf49'",479,656,537,557.333333333333,{"$nulls":4},"GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016589///NURF complex+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006325///chromatin organization","chromosome 17 open reading frame 49","[BAP18_HUMAN|Reviewed]RecName: Full=Chromatin complexes subunit BAP18; AltName: Full=BPTF-associated protein of 18 kDa;+++[F8W038_HUMAN|Unreviewed]SubName: Full=Chromosome 17 open reading frame 49 {ECO:0000313|Ensembl:ENSP00000447646};+++[F8W1H0_HUMAN|Unreviewed]SubName: Full=Chromosome 17 open reading frame 49 {ECO:0000313|Ensembl:ENSP00000447063};+++[K7ES76_HUMAN|Unreviewed]SubName: Full=Chromosome 17 open reading frame 49 {ECO:0000313|Ensembl:ENSP00000468587}; Flags: Fragment;"]
[125206,"'SLC5A10'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0022857///transmembrane transporter activity+++GO:0015370///solute:sodium symporter activity","GO:0055085///transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0008645///hexose transmembrane transport+++GO:0035725///sodium ion transmembrane transport","solute carrier family 5 member 10","[SC5AA_HUMAN|Reviewed]RecName: Full=Sodium/glucose cotransporter 5; Short=Na(+)/glucose cotransporter 5; AltName: Full=Solute carrier family 5 member 10;"]
[126070,"'ZNF440'",77,74.88,67,72.96,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 440","[ZN440_HUMAN|Reviewed]RecName: Full=Zinc finger protein 440;+++[C9J3D9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 440 {ECO:0000313|Ensembl:ENSP00000411974}; Flags: Fragment;+++[C9JG89_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 440 {ECO:0000313|Ensembl:ENSP00000404425}; Flags: Fragment;+++[C9JV94_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 440 {ECO:0000313|Ensembl:ENSP00000393489}; Flags: Fragment;+++[K7EJ55_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 440 {ECO:0000313|Ensembl:ENSP00000465030}; Flags: Fragment;+++[Q05DD3_HUMAN|Unreviewed]SubName: Full=ZNF440 protein {ECO:0000313|EMBL:AAH16371.1};"]
[126208,"'ZNF787'",396,381,404,393.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 787","[ZN787_HUMAN|Reviewed]RecName: Full=Zinc finger protein 787; AltName: Full=TTF-I-interacting peptide 20;+++[K7EKJ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 787 {ECO:0000313|Ensembl:ENSP00000465647};+++[M0R0X7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 787 {ECO:0000313|Ensembl:ENSP00000471514}; Flags: Fragment;"]
[126520,"'PLK5'",68,45,90,67.6666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0030154///cell differentiation+++GO:0051301///cell division+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0010976///positive regulation of neuron projection development+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0002357///defense response to tumor cell+++GO:0042981///regulation of apoptotic process+++GO:0071363///cellular response to growth factor stimulus","polo like kinase 5","[PLK5_HUMAN|Reviewed]RecName: Full=Inactive serine/threonine-protein kinase PLK5; AltName: Full=Polo-like kinase 5; Short=PLK-5;+++[A0A286YFL1_HUMAN|Unreviewed]SubName: Full=Inactive serine/threonine-protein kinase PLK5 {ECO:0000313|Ensembl:ENSP00000493341};"]
[1267,"'CNP'",1633,1665,1609,1635.66666666667,{"$nulls":4},"GO:0042470///melanosome+++GO:0031143///pseudopodium+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005615///extracellular space+++GO:0005856///cytoskeleton+++GO:0005902///microvillus+++GO:0005874///microtubule+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0005743///mitochondrial inner membrane+++GO:0035748///myelin sheath abaxonal region+++GO:0035749///myelin sheath adaxonal region","GO:0030551///cyclic nucleotide binding+++GO:0031072///heat shock protein binding+++GO:0003723///RNA binding+++GO:0001671///ATPase activator activity+++GO:0004113///2',3'-cyclic-nucleotide 3'-phosphodiesterase activity","GO:0007268///chemical synaptic transmission+++GO:0008344///adult locomotory behavior+++GO:0021762///substantia nigra development+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0006457///protein folding+++GO:0032496///response to lipopolysaccharide+++GO:0000226///microtubule cytoskeleton organization+++GO:0048709///oligodendrocyte differentiation+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0009636///response to toxic substance+++GO:0007409///axonogenesis+++GO:0007568///aging+++GO:0030900///forebrain development+++GO:1900034///regulation of cellular response to heat+++GO:0009214///cyclic nucleotide catabolic process","2',3'-cyclic nucleotide 3' phosphodiesterase","[CN37_HUMAN|Reviewed]RecName: Full=2',3'-cyclic-nucleotide 3'-phosphodiesterase; Short=CNP; Short=CNPase; EC=3.1.4.37; Flags: Precursor;+++[A0A024R1T5_HUMAN|Unreviewed]RecName: Full=2',3'-cyclic-nucleotide 3'-phosphodiesterase {ECO:0000256|PIRNR:PIRNR000970}; Short=CNP {ECO:0000256|PIRNR:PIRNR000970}; Short=CNPase {ECO:0000256|PIRNR:PIRNR000970}; EC=3.1.4.37 {ECO:0000256|PIRNR:PIRNR000970};"]
[127294,"'MYOM3'",8,9,9,8.66666666666667,{"$nulls":4},"GO:0005865///striated muscle thin filament+++GO:0005737///cytoplasm+++GO:0030017///sarcomere+++GO:0031430///M band+++GO:0030018///Z disc","GO:0008307///structural constituent of muscle+++GO:0051371///muscle alpha-actinin binding+++GO:0042803///protein homodimerization activity+++GO:0051015///actin filament binding","GO:0045214///sarcomere organization+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0055003///cardiac myofibril assembly+++GO:0048739///cardiac muscle fiber development+++GO:0030240///skeletal muscle thin filament assembly+++GO:0006936///muscle contraction+++GO:0055008///cardiac muscle tissue morphogenesis","myomesin 3","[MYOM3_HUMAN|Reviewed]RecName: Full=Myomesin-3; AltName: Full=Myomesin family member 3;"]
[127550,"'A3GALT2'",0,1,0,0.333333333333333,"01100///Metabolic pathways+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series",null,null,"R11320///UDP-D-galactose + Lactosylceramide <=> UDP + iGb3-Cer","GO:0031982///vesicle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032580///Golgi cisterna membrane","GO:0016758///transferase activity, transferring hexosyl groups+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047276///N-acetyllactosaminide 3-alpha-galactosyltransferase activity+++GO:0046872///metal ion binding+++GO:0001962///alpha-1,3-galactosyltransferase activity","GO:0006688///glycosphingolipid biosynthetic process+++GO:0005975///carbohydrate metabolic process+++GO:0030259///lipid glycosylation","alpha 1,3-galactosyltransferase 2","[A3LT2_HUMAN|Reviewed]RecName: Full=Alpha-1,3-galactosyltransferase 2 {ECO:0000312|HGNC:HGNC:30005}; EC=2.4.1.87 {ECO:0000305|PubMed:23378701}; AltName: Full=Isoglobotriaosylceramide synthase; Short=iGb3 synthase {ECO:0000303|PubMed:18630988}; Short=iGb3S {ECO:0000303|PubMed:18630988};"]
[127933,"'UHMK1'",815,451,582,616,{"$nulls":4},"GO:0071598///neuronal ribonucleoprotein granule+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0032839///dendrite cytoplasm+++GO:0030424///axon","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0004672///protein kinase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding","GO:0016310///phosphorylation+++GO:0031175///neuron projection development+++GO:0006468///protein phosphorylation+++GO:0045948///positive regulation of translational initiation+++GO:0046777///protein autophosphorylation+++GO:0046825///regulation of protein export from nucleus+++GO:0007050///cell cycle arrest+++GO:0018105///peptidyl-serine phosphorylation","U2AF homology motif kinase 1","[UHMK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Kist; EC=2.7.11.1; AltName: Full=Kinase interacting with stathmin; AltName: Full=PAM COOH-terminal interactor protein 2; Short=P-CIP2; AltName: Full=U2AF homology motif kinase 1;"]
[128486,"'FITM2'",201.65,189.4,241.12,210.723333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0035356///cellular triglyceride homeostasis+++GO:0022604///regulation of cell morphogenesis+++GO:0007010///cytoskeleton organization+++GO:0008654///phospholipid biosynthetic process+++GO:0034389///lipid droplet organization+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0019915///lipid storage+++GO:0010866///regulation of triglyceride biosynthetic process+++GO:0030730///sequestering of triglyceride","fat storage inducing transmembrane protein 2","[FITM2_HUMAN|Reviewed]RecName: Full=Fat storage-inducing transmembrane protein 2; AltName: Full=Fat-inducing protein 2;"]
[1287,"'COL4A5'",1090,994,966,1016.66666666667,"05165///Human papillomavirus infection+++04151///PI3K-Akt signaling pathway+++04512///ECM-receptor interaction+++04510///Focal adhesion+++04974///Protein digestion and absorption+++05222///Small cell lung cancer+++05200///Pathways in cancer+++04926///Relaxin signaling pathway+++05146///Amoebiasis+++04933///AGE-RAGE signaling pathway in diabetic complications","H00839///Porencephaly+++H01640///Uterine leiomyoma+++H00582///Benign familial hematuria+++H00877///Brain small vessel disease with hemorrhage+++H00579///Hereditary angiopathy with nephropathy, aneurysms, and muscle cramps (HANAC)+++H00581///Alport syndrome",null,null,"GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0031594///neuromuscular junction+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix","GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength","GO:0030198///extracellular matrix organization+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0007528///neuromuscular junction development","collagen type IV alpha 5 chain","[CO4A5_HUMAN|Reviewed]RecName: Full=Collagen alpha-5(IV) chain; Flags: Precursor;+++[A0A0A0U994_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha 5 transcript variant 2 {ECO:0000313|EMBL:AIW39922.1};+++[A0A2R8Y5W0_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000495101};+++[A7MBN3_HUMAN|Unreviewed]SubName: Full=Collagen, type IV, alpha 5 {ECO:0000313|EMBL:AAI51847.1};+++[H0Y998_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000423520}; Flags: Fragment;+++[H0Y9H0_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000424137}; Flags: Fragment;+++[H0Y9R8_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000424845}; Flags: Fragment;+++[Q49AM6_HUMAN|Unreviewed]SubName: Full=COL4A5 protein {ECO:0000313|EMBL:AAH35387.1}; SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000495685};+++[V9H0C7_HUMAN|Unreviewed]SubName: Full=COL4A5 protein {ECO:0000313|EMBL:AAC60613.1}; Flags: Fragment;"]
[129563,"'DIS3L2'",287,274,316,292.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01412///Perlman syndrome",null,null,"GO:0000178///exosome (RNase complex)+++GO:0005844///polysome+++GO:0005737///cytoplasm+++GO:0000932///P-body","GO:0008266///poly(U) RNA binding+++GO:0004540///ribonuclease activity+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding+++GO:0004527///exonuclease activity+++GO:0003723///RNA binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0000287///magnesium ion binding","GO:1990074///polyuridylation-dependent mRNA catabolic process+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0000291///nuclear-transcribed mRNA catabolic process, exonucleolytic+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0051306///mitotic sister chromatid separation+++GO:0007049///cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0010587///miRNA catabolic process+++GO:0006401///RNA catabolic process+++GO:0019827///stem cell population maintenance+++GO:0000278///mitotic cell cycle+++GO:0006364///rRNA processing+++GO:0051301///cell division","DIS3 like 3'-5' exoribonuclease 2","[DI3L2_HUMAN|Reviewed]RecName: Full=DIS3-like exonuclease 2 {ECO:0000255|HAMAP-Rule:MF_03045}; Short=hDIS3L2; EC=3.1.13.- {ECO:0000255|HAMAP-Rule:MF_03045};+++[C9JGP4_HUMAN|Unreviewed]SubName: Full=DIS3-like exonuclease 2 {ECO:0000313|Ensembl:ENSP00000390467}; Flags: Fragment;+++[H7C036_HUMAN|Unreviewed]SubName: Full=DIS3-like exonuclease 2 {ECO:0000313|Ensembl:ENSP00000392754}; Flags: Fragment;+++[H7C1Q8_HUMAN|Unreviewed]SubName: Full=DIS3-like exonuclease 2 {ECO:0000313|Ensembl:ENSP00000401700}; Flags: Fragment;+++[H7C302_HUMAN|Unreviewed]SubName: Full=DIS3-like exonuclease 2 {ECO:0000313|Ensembl:ENSP00000408764}; Flags: Fragment;+++[H7C440_HUMAN|Unreviewed]SubName: Full=DIS3-like exonuclease 2 {ECO:0000313|Ensembl:ENSP00000415419}; Flags: Fragment;"]
[129685,"'TAF8'",202.44,186,226.98,205.14,"03022///Basal transcription factors",{"$nulls":3},"GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0045598///regulation of fat cell differentiation+++GO:0030154///cell differentiation+++GO:0051457///maintenance of protein location in nucleus+++GO:0001833///inner cell mass cell proliferation+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045893///positive regulation of transcription, DNA-templated","TATA-box binding protein associated factor 8","[TAF8_HUMAN|Reviewed]RecName: Full=Transcription initiation factor TFIID subunit 8; AltName: Full=Protein taube nuss; AltName: Full=TBP-associated factor 43 kDa; AltName: Full=TBP-associated factor 8; AltName: Full=Transcription initiation factor TFIID 43 kDa subunit; Short=TAFII-43; Short=TAFII43; Short=hTAFII43;+++[A0A024RD01_HUMAN|Unreviewed]SubName: Full=Taube nuss homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAX04079.1};+++[A0A0A0MRR3_HUMAN|Unreviewed]SubName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000313|Ensembl:ENSP00000362069};+++[B4DZU5_HUMAN|Unreviewed]SubName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000313|Ensembl:ENSP00000418029}; SubName: Full=cDNA FLJ57866, highly similar to Homo sapiens TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, mRNA {ECO:0000313|EMBL:BAG64207.1};+++[C9J7M8_HUMAN|Unreviewed]SubName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000313|Ensembl:ENSP00000417760};+++[C9J856_HUMAN|Unreviewed]SubName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000313|Ensembl:ENSP00000417738};"]
[130026,"'ICA1L'",57.14,50.14,70.82,59.3666666666667,{"$nulls":4},"GO:0001669///acrosomal vesicle","GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0007286///spermatid development","islet cell autoantigen 1 like","[ICA1L_HUMAN|Reviewed]RecName: Full=Islet cell autoantigen 1-like protein; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 14 protein; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 15 protein;+++[A0A024R3W3_HUMAN|Unreviewed]SubName: Full=HCG2043051, isoform CRA_a {ECO:0000313|EMBL:EAW70316.1};+++[C9J0T2_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000400249}; Flags: Fragment;+++[C9J101_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000412158};+++[C9J1M7_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000392609}; Flags: Fragment;+++[C9J5Z0_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000397827}; Flags: Fragment;+++[C9J9Z8_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000405592}; Flags: Fragment;+++[C9JAQ4_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000410747}; Flags: Fragment;+++[C9JDK6_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000416726}; Flags: Fragment;+++[C9JDM8_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000404707}; Flags: Fragment;+++[C9JEN4_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000410135}; Flags: Fragment;+++[C9JEP0_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000404618}; Flags: Fragment;+++[C9JP49_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000414916}; Flags: Fragment;+++[C9JRB6_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000409741}; Flags: Fragment;+++[F8WBK1_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000398420};+++[F8WBQ1_HUMAN|Unreviewed]SubName: Full=Islet cell autoantigen 1-like protein {ECO:0000313|Ensembl:ENSP00000398916};+++[Q96Q33_HUMAN|Unreviewed]SubName: Full=ALS2CR14 protein {ECO:0000313|EMBL:BAB69024.1}; SubName: Full=Islet cell autoantigen 1,69kDa-like {ECO:0000313|EMBL:AAH93902.1};"]
[130540,"'ALS2CR12'",4,1,0,1.66666666666667,"04932///Non-alcoholic fatty liver disease (NAFLD)+++05163///Human cytomegalovirus infection+++04668///TNF signaling pathway+++05134///Legionellosis+++05016///Huntington's disease+++01524///Platinum drug resistance+++04621///NOD-like receptor signaling pathway+++05145///Toxoplasmosis+++04620///Toll-like receptor signaling pathway+++05161///Hepatitis B+++04622///RIG-I-like receptor signaling pathway+++04657///IL-17 signaling pathway+++05168///Herpes simplex infection+++04215///Apoptosis - multiple species+++04140///Autophagy - animal+++04137///Mitophagy - animal+++05203///Viral carcinogenesis+++04624///Toll and Imd signaling pathway+++05010///Alzheimer's disease+++05200///Pathways in cancer+++04217///Necroptosis+++04115///p53 signaling pathway+++04214///Apoptosis - fly+++04210///Apoptosis+++05152///Tuberculosis+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05165///Human papillomavirus infection+++05416///Viral myocarditis+++05142///Chagas disease (American trypanosomiasis)+++04625///C-type lectin receptor signaling pathway","H00108///Autoimmune lymphoproliferative syndromes (ALPS)",null,null,"GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0005929///cilium","GO:0005515///protein binding+++GO:0003674///molecular_function",null,"amyotrophic lateral sclerosis 2 chromosome region 12","[AL2SB_HUMAN|Reviewed]RecName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein;+++[A8K8B8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77510, highly similar to Homo sapiens amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12, mRNA {ECO:0000313|EMBL:BAF84972.1};+++[C9JTY0_HUMAN|Unreviewed]SubName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein {ECO:0000313|Ensembl:ENSP00000407585}; Flags: Fragment;+++[C9JZS0_HUMAN|Unreviewed]SubName: Full=Amyotrophic lateral sclerosis 2 (Juvenile) chromosome region, candidate 12, isoform CRA_b {ECO:0000313|EMBL:EAW70268.1}; SubName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein {ECO:0000313|Ensembl:ENSP00000393945}; Flags: Fragment;+++[H7C1T5_HUMAN|Unreviewed]SubName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein {ECO:0000313|Ensembl:ENSP00000402327}; Flags: Fragment;"]
[130814,"'PQLC3'",93,68,80,80.3333333333333,"04140///Autophagy - animal+++04270///Vascular smooth muscle contraction+++04062///Chemokine signaling pathway+++05163///Human cytomegalovirus infection+++05132///Salmonella infection+++04137///Mitophagy - animal+++04310///Wnt signaling pathway+++04530///Tight junction+++04360///Axon guidance+++04071///Sphingolipid signaling pathway+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++05200///Pathways in cancer+++04921///Oxytocin signaling pathway+++04611///Platelet activation+++04670///Leukocyte transendothelial migration+++04024///cAMP signaling pathway+++04022///cGMP-PKG signaling pathway+++04510///Focal adhesion+++05205///Proteoglycans in cancer",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005198///structural molecule activity+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0017048///Rho GTPase binding+++GO:0005524///ATP binding+++GO:0072518///Rho-dependent protein serine/threonine kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:1990776///response to angiotensin+++GO:0150033///negative regulation of protein localization to lysosome+++GO:0001934///positive regulation of protein phosphorylation+++GO:1903140///regulation of establishment of endothelial barrier+++GO:0030335///positive regulation of cell migration+++GO:0007266///Rho protein signal transduction+++GO:0071394///cellular response to testosterone stimulus+++GO:1903347///negative regulation of bicellular tight junction assembly+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0090271///positive regulation of fibroblast growth factor production+++GO:0043410///positive regulation of MAPK cascade+++GO:0070168///negative regulation of biomineral tissue development+++GO:0072659///protein localization to plasma membrane+++GO:0048013///ephrin receptor signaling pathway+++GO:1902004///positive regulation of amyloid-beta formation+++GO:0051893///regulation of focal adhesion assembly+++GO:0110061///regulation of angiotensin-activated signaling pathway+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0030155///regulation of cell adhesion+++GO:0071559///response to transforming growth factor beta+++GO:0006468///protein phosphorylation+++GO:0051492///regulation of stress fiber assembly+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0032723///positive regulation of connective tissue growth factor production+++GO:0051246///regulation of protein metabolic process+++GO:1902993///positive regulation of amyloid precursor protein catabolic process+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0042752///regulation of circadian rhythm+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0018105///peptidyl-serine phosphorylation+++GO:2000114///regulation of establishment of cell polarity+++GO:0035509///negative regulation of myosin-light-chain-phosphatase activity+++GO:0010595///positive regulation of endothelial cell migration+++GO:0039694///viral RNA genome replication+++GO:0010825///positive regulation of centrosome duplication+++GO:1902966///positive regulation of protein localization to early endosome+++GO:0016525///negative regulation of angiogenesis+++GO:0051496///positive regulation of stress fiber assembly+++GO:2000145///regulation of cell motility+++GO:0048511///rhythmic process+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030866///cortical actin cytoskeleton organization+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:1902961///positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process+++GO:0045616///regulation of keratinocyte differentiation+++GO:0051298///centrosome duplication+++GO:0006939///smooth muscle contraction+++GO:1905205///positive regulation of connective tissue replacement+++GO:0010628///positive regulation of gene expression","PQ loop repeat containing 3","[PQLC3_HUMAN|Reviewed]RecName: Full=PQ-loop repeat-containing protein 3; Flags: Precursor;+++[B5MC27_HUMAN|Unreviewed]SubName: Full=PQ-loop repeat-containing protein 3 {ECO:0000313|Ensembl:ENSP00000384129};+++[C9J4B6_HUMAN|Unreviewed]SubName: Full=PQ-loop repeat-containing protein 3 {ECO:0000313|Ensembl:ENSP00000410430}; Flags: Fragment;+++[G5E9P4_HUMAN|Unreviewed]SubName: Full=PQ loop repeat containing 3, isoform CRA_b {ECO:0000313|EMBL:EAX00940.1}; SubName: Full=PQ-loop repeat-containing protein 3 {ECO:0000313|Ensembl:ENSP00000406587};+++[H7C493_HUMAN|Unreviewed]SubName: Full=PQ-loop repeat-containing protein 3 {ECO:0000313|Ensembl:ENSP00000416170}; Flags: Fragment;"]
[131408,"'FAM131A'",169,181,166,172,{"$nulls":4},"GO:0005576///extracellular region",null,null,"family with sequence similarity 131 member A","[F131A_HUMAN|Reviewed]RecName: Full=Protein FAM131A; Flags: Precursor;+++[A0A1W2PQP7_HUMAN|Unreviewed]SubName: Full=Protein FAM131A {ECO:0000313|Ensembl:ENSP00000491845};+++[C9JP51_HUMAN|Unreviewed]SubName: Full=Protein FAM131A {ECO:0000313|Ensembl:ENSP00000414913}; Flags: Fragment;+++[C9JPT9_HUMAN|Unreviewed]SubName: Full=Protein FAM131A {ECO:0000313|Ensembl:ENSP00000414050};+++[C9JY59_HUMAN|Unreviewed]SubName: Full=Protein FAM131A {ECO:0000313|Ensembl:ENSP00000399875}; Flags: Fragment;"]
[131870,"'NUDT16'",547,391,476,471.333333333333,"00230///Purine metabolism+++03018///RNA degradation",null,null,"R10235///deoxyinosine diphosphate phosphatase   dIDP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Orthophosphate+++R10815///5'-(N7-methylguanosine 5'-triphospho)-[mRNA] N7-methylguanosine-5'-diphosphate phosphohydrolase   m7G(5')pppR-mRNA + H2O <=> N7-Methylguanosine 5'-diphosphate + 5'-Phospho-[mRNA]+++R00961///IDP phosphohydrolase; inosine   IDP + H2O <=> IMP + Orthophosphate","GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:1901640///XTP binding+++GO:1990174///phosphodiesterase decapping endonuclease activity+++GO:0030145///manganese ion binding+++GO:0050897///cobalt ion binding+++GO:0000287///magnesium ion binding+++GO:0005525///GTP binding+++GO:0031404///chloride ion binding+++GO:0035870///dITP diphosphatase activity+++GO:1990003///IDP phosphatase activity+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0098519///nucleotide phosphatase activity, acting on free nucleotides+++GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0097383///dIDP diphosphatase activity+++GO:0008235///metalloexopeptidase activity+++GO:1901641///ITP binding+++GO:0003729///mRNA binding+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding","GO:2000781///positive regulation of double-strand break repair+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0006382///adenosine to inosine editing+++GO:0016077///snoRNA catabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:1901639///XDP catabolic process+++GO:0090068///positive regulation of cell cycle process+++GO:0016311///dephosphorylation+++GO:2000233///negative regulation of rRNA processing+++GO:0035863///dITP catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0006508///proteolysis+++GO:0034656///nucleobase-containing small molecule catabolic process+++GO:0006402///mRNA catabolic process+++GO:0046709///IDP catabolic process","nudix hydrolase 16","[NUD16_HUMAN|Reviewed]RecName: Full=U8 snoRNA-decapping enzyme; EC=3.6.1.62 {ECO:0000269|PubMed:15053875, ECO:0000269|PubMed:17567574, ECO:0000269|PubMed:18820299, ECO:0000269|PubMed:21070968, ECO:0000269|PubMed:21337011}; AltName: Full=IDP phosphatase; Short=IDPase; EC=3.6.1.64 {ECO:0000269|PubMed:20385596, ECO:0000269|PubMed:26121039}; AltName: Full=Inosine diphosphate phosphatase; AltName: Full=Nucleoside diphosphate-linked moiety X motif 16; Short=Nudix motif 16; AltName: Full=Nudix hydrolase 16; AltName: Full=U8 snoRNA-binding protein H29K {ECO:0000303|PubMed:17567574}; AltName: Full=m7GpppN-mRNA hydrolase;"]
[132332,"'TMEM155'",941,855,927,907.666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005576///extracellular region",null,null,"transmembrane protein 155","[TM155_HUMAN|Reviewed]RecName: Full=Protein TMEM155; Flags: Precursor;+++[A0A2R8YEN4_HUMAN|Unreviewed]SubName: Full=Protein TMEM155 {ECO:0000313|Ensembl:ENSP00000495721};+++[D6R9V5_HUMAN|Unreviewed]SubName: Full=Protein TMEM155 {ECO:0000313|Ensembl:ENSP00000422869}; Flags: Fragment;"]
[132989,"'C4orf36'",0,0,1,0.333333333333333,"05202///Transcriptional misregulation in cancer","H00001///B lymphoblastic leukemia/lymphoma",null,null,"GO:0008023///transcription elongation factor complex","GO:0003700///DNA-binding transcription factor activity",null,"chromosome 4 open reading frame 36","[CD036_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C4orf36;+++[D6RAE1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C4orf36 {ECO:0000313|Ensembl:ENSP00000422720}; Flags: Fragment;+++[D6RCP1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C4orf36 {ECO:0000313|Ensembl:ENSP00000427122};+++[D6RF10_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C4orf36 {ECO:0000313|Ensembl:ENSP00000421568};+++[D6RGW9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C4orf36 {ECO:0000313|Ensembl:ENSP00000421141}; Flags: Fragment;"]
[133957,"'CCDC127'",236,239,247,240.666666666667,"04714///Thermogenesis+++01130///Biosynthesis of antibiotics+++05016///Huntington's disease+++00020///Citrate cycle (TCA cycle)+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease+++01100///Metabolic pathways+++04140///Autophagy - animal+++01200///Carbon metabolism+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++01120///Microbial metabolism in diverse environments+++04137///Mitophagy - animal+++01110///Biosynthesis of secondary metabolites","H00294///Dilated cardiomyopathy (DCM)+++H01354///Leigh syndrome+++H01022///Diseases of the tricarboxylic acid cycle+++H02005///Mitochondrial complex II deficiency","M00011///Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate+++M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00148///Succinate dehydrogenase (ubiquinone)","R02164///succinate:quinone oxidoreductase Quinone + Succinate <=> Hydroquinone + Fumarate","GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008177///succinate dehydrogenase (ubiquinone) activity+++GO:0009055///electron transfer activity+++GO:0050660///flavin adenine dinucleotide binding","GO:0006105///succinate metabolic process+++GO:0006121///mitochondrial electron transport, succinate to ubiquinone+++GO:0006099///tricarboxylic acid cycle+++GO:0007399///nervous system development+++GO:0022904///respiratory electron transport chain+++GO:0055114///oxidation-reduction process+++GO:0009061///anaerobic respiration","coiled-coil domain containing 127","[CC127_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 127;+++[D6R9R2_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 127 {ECO:0000313|Ensembl:ENSP00000411206}; Flags: Fragment;"]
[134510,"'UBLCP1'",476,415,439,443.333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0006470///protein dephosphorylation","ubiquitin like domain containing CTD phosphatase 1","[UBCP1_HUMAN|Reviewed]RecName: Full=Ubiquitin-like domain-containing CTD phosphatase 1; EC=3.1.3.16; AltName: Full=Nuclear proteasome inhibitor UBLCP1;"]
[135112,"'NCOA7'",957,672,549,726,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005622///intracellular","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0035257///nuclear hormone receptor binding+++GO:0005515///protein binding","GO:1900408///negative regulation of cellular response to oxidative stress+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation","nuclear receptor coactivator 7","[NCOA7_HUMAN|Reviewed]RecName: Full=Nuclear receptor coactivator 7; AltName: Full=140 kDa estrogen receptor-associated protein; AltName: Full=Estrogen nuclear receptor coactivator 1;+++[B3KXK4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45605 fis, clone BRTHA3021971, highly similar to Nuclear receptor coactivator 7 {ECO:0000313|EMBL:BAG54516.1};+++[H0UI55_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 7, isoform CRA_c {ECO:0000313|EMBL:EAW48134.1};+++[H0Y5F6_HUMAN|Unreviewed]SubName: Full=NCOA7-AS {ECO:0000313|EMBL:AGW32499.1};+++[H0Y6T0_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 7 {ECO:0000313|Ensembl:ENSP00000407684};+++[Q3LID7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla00052 {ECO:0000313|EMBL:BAE45731.1}; Flags: Fragment;+++[Q5TF96_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 7 {ECO:0000313|Ensembl:ENSP00000406363}; Flags: Fragment;+++[Q5TF97_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 7 {ECO:0000313|Ensembl:ENSP00000408211}; Flags: Fragment;+++[Q5TF98_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 7 {ECO:0000313|Ensembl:ENSP00000407426}; Flags: Fragment;+++[Q6PK00_HUMAN|Unreviewed]SubName: Full=NCOA7 protein {ECO:0000313|EMBL:AAH09399.1}; Flags: Fragment;+++[Q8N3C8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp761B2210 {ECO:0000313|EMBL:CAD39102.1}; Flags: Fragment;+++[Q8N4U9_HUMAN|Unreviewed]SubName: Full=NCOA7 protein {ECO:0000313|EMBL:AAH33612.1}; Flags: Fragment;"]
[135941,"'OR2A14'",3.05,0,2.97,2.00666666666667,"04740///Olfactory transduction",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004984///olfactory receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0050896///response to stimulus+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007608///sensory perception of smell+++GO:0007165///signal transduction","olfactory receptor family 2 subfamily A member 14","[O2A14_HUMAN|Reviewed]RecName: Full=Olfactory receptor 2A14; AltName: Full=OST182; AltName: Full=Olfactory receptor 2A6; AltName: Full=Olfactory receptor OR7-12;+++[A0A126GVB0_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};"]
[1365,"'CLDN3'",443,521,599,521,"05160///Hepatitis C+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++04514///Cell adhesion molecules (CAMs)","H00742///Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome+++H00605///Deafness, autosomal recessive+++H01439///Williams-Beuren syndrome+++H01210///Hypomagnesemia",null,null,"GO:0005923///bicellular tight junction+++GO:0016328///lateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0016020///membrane","GO:0042802///identical protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005198///structural molecule activity","GO:0051291///protein heterooligomerization+++GO:0001666///response to hypoxia+++GO:0051260///protein homooligomerization+++GO:0070830///bicellular tight junction assembly+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:0003382///epithelial cell morphogenesis+++GO:0045471///response to ethanol","claudin 3","[CLD3_HUMAN|Reviewed]RecName: Full=Claudin-3; AltName: Full=Clostridium perfringens enterotoxin receptor 2; Short=CPE-R 2; Short=CPE-receptor 2; AltName: Full=Rat ventral prostate.1 protein homolog; Short=hRVP1;+++[Q75L79_HUMAN|Unreviewed]RecName: Full=Claudin {ECO:0000256|RuleBase:RU060637};"]
[1378,"'CR1'",1,0,3,1.33333333333333,"05134///Legionellosis+++04640///Hematopoietic cell lineage+++04610///Complement and coagulation cascades+++05140///Leishmaniasis+++05144///Malaria+++05152///Tuberculosis",{"$nulls":3},"GO:0030667///secretory granule membrane+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0001855///complement component C4b binding+++GO:0004877///complement component C3b receptor activity+++GO:0001861///complement component C4b receptor activity+++GO:0001618///virus receptor activity+++GO:0001851///complement component C3b binding","GO:0002376///immune system process+++GO:1900005///positive regulation of serine-type endopeptidase activity+++GO:0002430///complement receptor mediated signaling pathway+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:0043312///neutrophil degranulation+++GO:0045087///innate immune response+++GO:0046718///viral entry into host cell+++GO:0030449///regulation of complement activation+++GO:0045957///negative regulation of complement activation, alternative pathway+++GO:0006958///complement activation, classical pathway+++GO:0016032///viral process+++GO:0045589///regulation of regulatory T cell differentiation+++GO:1900004///negative regulation of serine-type endopeptidase activity","complement C3b/C4b receptor 1 (Knops blood group)","[CR1_HUMAN|Reviewed]RecName: Full=Complement receptor type 1; AltName: Full=C3b/C4b receptor; AltName: CD_antigen=CD35; Flags: Precursor;+++[A0A2S1GUW1_HUMAN|Unreviewed]SubName: Full=Complement receptor 1 {ECO:0000313|EMBL:AWD93587.1}; Flags: Fragment;+++[A0A2S1GUW8_HUMAN|Unreviewed]SubName: Full=Complement receptor 1 {ECO:0000313|EMBL:AWD93586.1}; Flags: Fragment;+++[E9PDY4_HUMAN|Unreviewed]SubName: Full=Complement receptor type 1 {ECO:0000313|Ensembl:ENSP00000356016};+++[E9PQN4_HUMAN|Unreviewed]SubName: Full=Complement receptor type 1 {ECO:0000313|Ensembl:ENSP00000436139};+++[H0YE06_HUMAN|Unreviewed]SubName: Full=Complement receptor type 1 {ECO:0000313|Ensembl:ENSP00000434718}; Flags: Fragment;+++[Q5SBJ5_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65577.1}; Flags: Fragment;+++[Q5SBJ6_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65576.1}; Flags: Fragment;+++[Q5SBJ7_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65575.1}; Flags: Fragment;+++[Q5SBJ8_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65574.1}; Flags: Fragment;+++[Q5SBJ9_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65573.1}; Flags: Fragment;+++[Q5SBK0_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65572.1}; Flags: Fragment;+++[Q5SBK1_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65571.1}; Flags: Fragment;+++[Q5SBK2_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65570.1}; Flags: Fragment;+++[Q5SBK3_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65569.1}; Flags: Fragment;+++[Q5SBK4_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65568.1}; Flags: Fragment;+++[Q5SBK5_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65567.1}; Flags: Fragment;+++[Q5SBK6_HUMAN|Unreviewed]SubName: Full=CR1 protein domain SCR25 {ECO:0000313|EMBL:AAV65566.1}; Flags: Fragment;+++[Q5SR44_HUMAN|Unreviewed]SubName: Full=Complement receptor type 1 {ECO:0000313|Ensembl:ENSP00000356019};+++[Q9HB98_HUMAN|Unreviewed]SubName: Full=Complement receptor type 1 {ECO:0000313|EMBL:AAG14443.1}; Flags: Fragment;+++[Q9HB99_HUMAN|Unreviewed]SubName: Full=Complement receptor type 1 {ECO:0000313|EMBL:AAG14442.1}; Flags: Fragment;+++[Q9HC54_HUMAN|Unreviewed]SubName: Full=Complement receptor 1 {ECO:0000313|EMBL:AAG09140.1}; Flags: Fragment;+++[Q9HC55_HUMAN|Unreviewed]SubName: Full=Complement receptor 1 {ECO:0000313|EMBL:AAG09139.1}; Flags: Fragment;+++[V6EYC3_HUMAN|Unreviewed]SubName: Full=Complement component (3b/4b) receptor 1 (Knops blood group) {ECO:0000313|EMBL:CDK60404.1}; Flags: Fragment;"]
[1381,"'CRABP1'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0001972///retinoic acid binding+++GO:0016918///retinal binding+++GO:0019841///retinol binding+++GO:0005501///retinoid binding","GO:0007275///multicellular organism development+++GO:0034653///retinoic acid catabolic process+++GO:0007165///signal transduction","cellular retinoic acid binding protein 1","[RABP1_HUMAN|Reviewed]RecName: Full=Cellular retinoic acid-binding protein 1; AltName: Full=Cellular retinoic acid-binding protein I; Short=CRABP-I;+++[B5MCB5_HUMAN|Unreviewed]SubName: Full=Cellular retinoic acid-binding protein 1 {ECO:0000313|Ensembl:ENSP00000385978}; Flags: Fragment;+++[F1T0F7_HUMAN|Unreviewed]SubName: Full=Cellular retinoic acid-binding protein 1 {ECO:0000313|EMBL:BAJ84031.1, ECO:0000313|EMBL:EAW99172.1};"]
[1389,"'CREBL2'",676,608,689,657.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0050821///protein stabilization+++GO:0045600///positive regulation of fat cell differentiation+++GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0046326///positive regulation of glucose import+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0007049///cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0006351///transcription, DNA-templated","cAMP responsive element binding protein like 2","[CRBL2_HUMAN|Reviewed]RecName: Full=cAMP-responsive element-binding protein-like 2;+++[A0A024RAX5_HUMAN|Unreviewed]SubName: Full=cAMP responsive element binding protein-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW96270.1}; Flags: Fragment;"]
[139378,"'ADGRG4'",1,0,2,1,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway","adhesion G protein-coupled receptor G4","[AGRG4_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor G4 {ECO:0000303|PubMed:25713288}; AltName: Full=G-protein coupled receptor 112; Flags: Precursor;"]
[139886,"'SPIN4'",24,15,19,19.3333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0035064///methylated histone binding+++GO:0005515///protein binding","GO:0007276///gamete generation","spindlin family member 4","[SPIN4_HUMAN|Reviewed]RecName: Full=Spindlin-4;+++[X6R8Y7_HUMAN|Unreviewed]SubName: Full=Spindlin-4 {ECO:0000313|Ensembl:ENSP00000364018};"]
[140458,"'ASB5'",6,3,5,4.66666666666667,{"$nulls":4},"GO:0005829///cytosol",null,"GO:0045732///positive regulation of protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction","ankyrin repeat and SOCS box containing 5","[ASB5_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 5; Short=ASB-5;+++[D6R9Q2_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 5 {ECO:0000313|Ensembl:ENSP00000423232}; Flags: Fragment;+++[Q5HYF3_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box-containing 5 {ECO:0000313|EMBL:EAX04720.1}; SubName: Full=cDNA FLJ39122 fis, clone NTONG2006783, weakly similar to ANKYRIN 1 {ECO:0000313|EMBL:BAC04791.1};"]
[140700,"'SAMD10'",338,383,360,360.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"sterile alpha motif domain containing 10","[SAM10_HUMAN|Reviewed]RecName: Full=Sterile alpha motif domain-containing protein 10; Short=SAM domain-containing protein 10;+++[Q5JWV3_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000404839}; Flags: Fragment;"]
[140733,"'MACROD2'",39,38,27,34.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005813///centrosome","GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016787///hydrolase activity+++GO:0019213///deacetylase activity","GO:0042278///purine nucleoside metabolic process+++GO:0009617///response to bacterium+++GO:0051725///protein de-ADP-ribosylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007420///brain development","MACRO domain containing 2","[MACD2_HUMAN|Reviewed]RecName: Full=O-acetyl-ADP-ribose deacetylase MACROD2; EC=3.2.2.-; EC=3.5.1.-; AltName: Full=MACRO domain-containing protein 2; AltName: Full=[Protein ADP-ribosylglutamate] hydrolase;+++[A0A2R8YFN3_HUMAN|Unreviewed]SubName: Full=O-acetyl-ADP-ribose deacetylase MACROD2 {ECO:0000313|Ensembl:ENSP00000496601};"]
[141,"'ADPRH'",200,179,191,190,{"$nulls":4},"GO:0005623///cell","GO:0030955///potassium ion binding+++GO:0005096///GTPase activator activity+++GO:0000287///magnesium ion binding+++GO:0005515///protein binding+++GO:0017137///Rab GTPase binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0003875///ADP-ribosylarginine hydrolase activity","GO:0051725///protein de-ADP-ribosylation+++GO:0006464///cellular protein modification process+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","ADP-ribosylarginine hydrolase","[ADPRH_HUMAN|Reviewed]RecName: Full=[Protein ADP-ribosylarginine] hydrolase; Short=ADP-ribosylarginine hydrolase; EC=3.2.2.19; AltName: Full=ADP-ribose-L-arginine cleaving enzyme;+++[A8K6X2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77992, highly similar to Homo sapiens ADP-ribosylarginine hydrolase, mRNA {ECO:0000313|EMBL:BAF84476.1};+++[B4E341_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50373, highly similar to Protein ADP-ribosylarginine hydrolase {ECO:0000313|EMBL:BAG65353.1};+++[C9JZW7_HUMAN|Unreviewed]SubName: Full=[Protein ADP-ribosylarginine] hydrolase {ECO:0000313|Ensembl:ENSP00000419703}; Flags: Fragment;"]
[142683,"'ITLN2'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0005576///extracellular region","GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding",null,"intelectin 2","[ITLN2_HUMAN|Reviewed]RecName: Full=Intelectin-2; AltName: Full=Endothelial lectin HL-2; Flags: Precursor;+++[L8E943_HUMAN|Unreviewed]SubName: Full=Alternative protein ITLN2 {ECO:0000313|EMBL:CCQ43820.1};"]
[1435,"'CSF1'",247,246,264,252.333333333333,"04010///MAPK signaling pathway+++04640///Hematopoietic cell lineage+++05323///Rheumatoid arthritis+++04668///TNF signaling pathway+++04015///Rap1 signaling pathway+++04380///Osteoclast differentiation+++04014///Ras signaling pathway+++04151///PI3K-Akt signaling pathway+++04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:1990682///CSF1-CSF1R complex+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane","GO:0042802///identical protein binding+++GO:0005125///cytokine activity+++GO:0005157///macrophage colony-stimulating factor receptor binding+++GO:0042803///protein homodimerization activity+++GO:0008083///growth factor activity+++GO:0005515///protein binding","GO:0038145///macrophage colony-stimulating factor signaling pathway+++GO:0060611///mammary gland fat development+++GO:0008284///positive regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0045087///innate immune response+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0045860///positive regulation of protein kinase activity+++GO:0044267///cellular protein metabolic process+++GO:1902228///positive regulation of macrophage colony-stimulating factor signaling pathway+++GO:0002376///immune system process+++GO:0040018///positive regulation of multicellular organism growth+++GO:0030316///osteoclast differentiation+++GO:0010628///positive regulation of gene expression+++GO:0030097///hemopoiesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0045657///positive regulation of monocyte differentiation+++GO:0008283///cell proliferation+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0010469///regulation of signaling receptor activity+++GO:0060763///mammary duct terminal end bud growth+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0006954///inflammatory response+++GO:0042488///positive regulation of odontogenesis of dentin-containing tooth+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0042117///monocyte activation+++GO:0002158///osteoclast proliferation+++GO:0030278///regulation of ossification+++GO:0003006///developmental process involved in reproduction+++GO:1904141///positive regulation of microglial cell migration+++GO:0010743///regulation of macrophage derived foam cell differentiation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0030154///cell differentiation+++GO:0045651///positive regulation of macrophage differentiation+++GO:0043687///post-translational protein modification+++GO:0030225///macrophage differentiation+++GO:0032946///positive regulation of mononuclear cell proliferation","colony stimulating factor 1","[CSF1_HUMAN|Reviewed]RecName: Full=Macrophage colony-stimulating factor 1; Short=CSF-1; Short=M-CSF; Short=MCSF; AltName: Full=Lanimostim; Contains: RecName: Full=Processed macrophage colony-stimulating factor 1; Flags: Precursor;+++[A0A024R0A1_HUMAN|Unreviewed]RecName: Full=Macrophage colony-stimulating factor 1 {ECO:0000256|PIRNR:PIRNR001948}; Short=CSF-1 {ECO:0000256|PIRNR:PIRNR001948}; Short=MCSF {ECO:0000256|PIRNR:PIRNR001948};+++[E9PJA2_HUMAN|Unreviewed]SubName: Full=Macrophage colony-stimulating factor 1 {ECO:0000313|Ensembl:ENSP00000433837}; Flags: Fragment;+++[E9PKP4_HUMAN|Unreviewed]SubName: Full=Macrophage colony-stimulating factor 1 {ECO:0000313|Ensembl:ENSP00000431547}; Flags: Fragment;+++[E9PQ08_HUMAN|Unreviewed]SubName: Full=Macrophage colony-stimulating factor 1 {ECO:0000313|Ensembl:ENSP00000434527}; Flags: Fragment;+++[H7BY18_HUMAN|Unreviewed]SubName: Full=Macrophage colony-stimulating factor 1 {ECO:0000313|Ensembl:ENSP00000349854}; Flags: Fragment;"]
[143872,"'ARHGAP42'",473,308,380,387,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0003085///negative regulation of systemic arterial blood pressure+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity+++GO:1904694///negative regulation of vascular smooth muscle contraction","Rho GTPase activating protein 42","[RHG42_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 42; AltName: Full=Rho GTPase-activating protein 10-like; AltName: Full=Rho-type GTPase-activating protein 42;+++[TM133_HUMAN|Reviewed]RecName: Full=Transmembrane protein 133;+++[A0A2X0SYU7_HUMAN|Unreviewed]SubName: Full=ARHGAP42 {ECO:0000313|EMBL:SPT35709.1}; Flags: Fragment;+++[E9PJK4_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 42 {ECO:0000313|Ensembl:ENSP00000431776};+++[H0YDU1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 42 {ECO:0000313|Ensembl:ENSP00000434304}; Flags: Fragment;+++[H0YEJ7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 42 {ECO:0000313|Ensembl:ENSP00000435961}; Flags: Fragment;+++[L8E964_HUMAN|Unreviewed]SubName: Full=Alternative protein ARHGAP42 {ECO:0000313|EMBL:CCQ43850.1};"]
[144402,"'CPNE8'",176,99,164,146.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005886///plasma membrane","GO:0005544///calcium-dependent phospholipid binding+++GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0071277///cellular response to calcium ion","copine 8","[CPNE8_HUMAN|Reviewed]RecName: Full=Copine-8 {ECO:0000305}; AltName: Full=Copine VIII {ECO:0000312|HGNC:HGNC:23498};+++[E7ENV7_HUMAN|Unreviewed]SubName: Full=Copine-8 {ECO:0000313|Ensembl:ENSP00000353633};+++[F8VZB5_HUMAN|Unreviewed]SubName: Full=Copine-8 {ECO:0000313|Ensembl:ENSP00000447761}; Flags: Fragment;"]
[144608,"'C12orf60'",22,20,16,19.3333333333333,"05034///Alcoholism+++04140///Autophagy - animal+++04217///Necroptosis+++05322///Systemic lupus erythematosus+++03040///Spliceosome+++04137///Mitophagy - animal+++00230///Purine metabolism","H01615///Irritable bowel syndrome+++H00500///Keutel syndrome+++H01174///Congenital diarrhea","M00353///Spliceosome, Prp19/CDC5L complex","R00434///GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming) GTP <=> 3',5'-Cyclic GMP + Diphosphate","GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0008074///guanylate cyclase complex, soluble+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0000786///nucleosome+++GO:0031012///extracellular matrix","GO:0005525///GTP binding+++GO:0004623///phospholipase A2 activity+++GO:0005509///calcium ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0050699///WW domain binding+++GO:0005524///ATP binding+++GO:0019888///protein phosphatase regulator activity+++GO:0008147///structural constituent of bone+++GO:0046982///protein heterodimerization activity+++GO:0005201///extracellular matrix structural constituent+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0003697///single-stranded DNA binding+++GO:0004622///lysophospholipase activity+++GO:0004383///guanylate cyclase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0015643///toxic substance binding+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity","GO:0001502///cartilage condensation+++GO:0030154///cell differentiation+++GO:0000398///mRNA splicing, via spliceosome+++GO:0032197///transposition, RNA-mediated+++GO:0016042///lipid catabolic process+++GO:0006310///DNA recombination+++GO:0007586///digestion+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0036149///phosphatidylinositol acyl-chain remodeling+++GO:0006364///rRNA processing+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0006182///cGMP biosynthetic process+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0001503///ossification+++GO:0006334///nucleosome assembly+++GO:0030500///regulation of bone mineralization+++GO:0006352///DNA-templated transcription, initiation+++GO:0007165///signal transduction+++GO:0045292///mRNA cis splicing, via spliceosome+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0009636///response to toxic substance+++GO:0042127///regulation of cell proliferation+++GO:0035556///intracellular signal transduction+++GO:0006644///phospholipid metabolic process","chromosome 12 open reading frame 60","[CL060_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C12orf60;"]
[1455,"'CSNK1G2'",2134,2369,2123,2208.66666666667,"04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0051219///phosphoprotein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0042277///peptide binding+++GO:0005524///ATP binding","GO:0016055///Wnt signaling pathway+++GO:0006897///endocytosis+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0030148///sphingolipid biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0018105///peptidyl-serine phosphorylation+++GO:0016310///phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway","casein kinase 1 gamma 2","[KC1G2_HUMAN|Reviewed]RecName: Full=Casein kinase I isoform gamma-2; Short=CKI-gamma 2; EC=2.7.11.1;+++[A0A087WW97_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-2 {ECO:0000313|Ensembl:ENSP00000480052}; Flags: Fragment;+++[A0A087WWF5_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-2 {ECO:0000313|Ensembl:ENSP00000480185}; Flags: Fragment;+++[A0A087WXD7_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-2 {ECO:0000313|Ensembl:ENSP00000480929}; Flags: Fragment;+++[A0A087WZK4_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-2 {ECO:0000313|Ensembl:ENSP00000482716}; Flags: Fragment;+++[K7EJC0_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-2 {ECO:0000313|Ensembl:ENSP00000465106}; Flags: Fragment;+++[K7EP38_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-2 {ECO:0000313|Ensembl:ENSP00000467214}; Flags: Fragment;+++[K7ESB6_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-2 {ECO:0000313|Ensembl:ENSP00000468637}; Flags: Fragment;"]
[145814,"'PGPEP1L'",3,5,5,4.33333333333333,{"$nulls":4},"GO:0005829///cytosol","GO:0016920///pyroglutamyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity","GO:0006508///proteolysis","pyroglutamyl-peptidase I like","[PGPIL_HUMAN|Reviewed]RecName: Full=Pyroglutamyl-peptidase 1-like protein; EC=3.4.19.-;+++[A0A1B0GWH3_HUMAN|Unreviewed]SubName: Full=Pyroglutamyl-peptidase 1-like protein {ECO:0000313|Ensembl:ENSP00000490927}; Flags: Fragment;"]
[145873,"'MESP2'",2,2,5,3,null,"H00517///Spondylocostal dysostosis (SCD)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0003007///heart morphogenesis+++GO:0001756///somitogenesis+++GO:0006357///regulation of transcription by RNA polymerase II","mesoderm posterior bHLH transcription factor 2","[MESP2_HUMAN|Reviewed]RecName: Full=Mesoderm posterior protein 2; AltName: Full=Class C basic helix-loop-helix protein 6; Short=bHLHc6;+++[H0YKZ5_HUMAN|Unreviewed]SubName: Full=Mesoderm posterior protein 2 {ECO:0000313|Ensembl:ENSP00000452998};"]
[146542,"'ZNF688'",156,160,132,149.333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0005575///cellular_component","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process","zinc finger protein 688","[ZN688_HUMAN|Reviewed]RecName: Full=Zinc finger protein 688;+++[A0A024QZB6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 688, isoform CRA_b {ECO:0000313|EMBL:EAW52236.1};+++[A0A0S2Z5X4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 688 isoform 4 {ECO:0000313|EMBL:ALQ34330.1}; Flags: Fragment;+++[A0A0S2Z633_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 688 isoform 1 {ECO:0000313|EMBL:ALQ34328.1}; Flags: Fragment;+++[A0A0S2Z6P0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 688 isoform 2 {ECO:0000313|EMBL:ALQ34329.1};+++[H3BR26_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 688 {ECO:0000313|Ensembl:ENSP00000456047}; Flags: Fragment;+++[H3BR45_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 688 {ECO:0000313|Ensembl:ENSP00000456070};+++[H3BTK8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 688 {ECO:0000313|Ensembl:ENSP00000457222};+++[L0R5I2_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF688 {ECO:0000313|EMBL:CCO13859.1};"]
[146562,"'C16orf71'",46,35,39,40,{"$nulls":7},"chromosome 16 open reading frame 71","[CP071_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C16orf71;+++[A0A087WT50_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf71 {ECO:0000313|Ensembl:ENSP00000477582}; Flags: Fragment;+++[K7ENX3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf71 {ECO:0000313|Ensembl:ENSP00000467133}; Flags: Fragment;+++[K7EPW6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf71 {ECO:0000313|Ensembl:ENSP00000467565};"]
[146853,"'C17orf50'",1,0,1,0.666666666666667,{"$nulls":7},"chromosome 17 open reading frame 50","[CQ050_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf50;+++[A0A075B7C2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf50 {ECO:0000313|Ensembl:ENSP00000474048};+++[A0A075B7E2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf50 {ECO:0000313|Ensembl:ENSP00000474618};"]
[147179,"'WIPF2'",1367,1229,1231,1275.66666666667,"04144///Endocytosis","H01523///Wiskott-Aldrich syndrome",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005884///actin filament+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030479///actin cortical patch","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0000147///actin cortical patch assembly+++GO:0051127///positive regulation of actin nucleation+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030048///actin filament-based movement+++GO:0006897///endocytosis+++GO:0051666///actin cortical patch localization","WAS/WASL interacting protein family member 2","[WIPF2_HUMAN|Reviewed]RecName: Full=WAS/WASL-interacting protein family member 2; AltName: Full=WASP-interacting protein-related protein; AltName: Full=WIP- and CR16-homologous protein; AltName: Full=WIP-related protein;+++[A0A024R1X2_HUMAN|Unreviewed]SubName: Full=WIRE protein, isoform CRA_a {ECO:0000313|EMBL:EAW60649.1};+++[A8MWR2_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000377663}; SubName: Full=cDNA FLJ30495 fis, clone BRAWH2000323, moderately similar to WIP-related protein {ECO:0000313|EMBL:BAG51456.1};+++[J3KSA3_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000462386}; Flags: Fragment;+++[J3QKM5_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000463149}; Flags: Fragment;+++[J3QQS0_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000463869};"]
[147660,"'ZNF578'",98,80.15,93.7,90.6166666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 578","[ZN578_HUMAN|Reviewed]RecName: Full=Zinc finger protein 578;+++[M0QZV4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 578 {ECO:0000313|Ensembl:ENSP00000470790}; Flags: Fragment;+++[Q3MI94_HUMAN|Unreviewed]SubName: Full=ZNF578 protein {ECO:0000313|EMBL:AAI03905.3}; Flags: Fragment;"]
[147808,"'ZNF784'",159,211,193,187.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0002244///hematopoietic progenitor cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger protein 784","[ZN784_HUMAN|Reviewed]RecName: Full=Zinc finger protein 784;+++[K7EQ92_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 784 {ECO:0000313|Ensembl:ENSP00000467725};"]
[148113,"'CILP2'",137,150,200,162.333333333333,"05010///Alzheimer's disease+++04723///Retrograde endocannabinoid signaling+++05016///Huntington's disease+++04714///Thermogenesis+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00146///NADH dehydrogenase (ubiquinone) 1 alpha subcomplex",null,"GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0004035///alkaline phosphatase activity+++GO:0004551///nucleotide diphosphatase activity","GO:0016311///dephosphorylation","cartilage intermediate layer protein 2","[CILP2_HUMAN|Reviewed]RecName: Full=Cartilage intermediate layer protein 2; Short=CILP-2; Contains: RecName: Full=Cartilage intermediate layer protein 2 C1; Contains: RecName: Full=Cartilage intermediate layer protein 2 C2; Flags: Precursor;+++[K7EPJ4_HUMAN|Unreviewed]SubName: Full=Cartilage intermediate layer protein 2, isoform CRA_b {ECO:0000313|EMBL:EAW84833.1};"]
[148304,"'C1orf74'",39,41,48,42.6666666666667,{"$nulls":7},"chromosome 1 open reading frame 74","[CA074_HUMAN|Reviewed]RecName: Full=UPF0739 protein C1orf74;+++[A0A0A8K8E6_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 74 {ECO:0000313|EMBL:EAW93440.1}; SubName: Full=Up-regulated in lung cancer 4 {ECO:0000313|EMBL:BAQ19750.1};"]
[148753,"'FAM163A'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"family with sequence similarity 163 member A","[F163A_HUMAN|Reviewed]RecName: Full=Protein FAM163A; AltName: Full=Cebelin; AltName: Full=Neuroblastoma-derived secretory protein;"]
[149297,"'FAM78B'",333,271,653,419,{"$nulls":7},"family with sequence similarity 78 member B","[FA78B_HUMAN|Reviewed]RecName: Full=Protein FAM78B;+++[F1T0K0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAJ84074.1};+++[H7C075_HUMAN|Unreviewed]SubName: Full=Protein FAM78B {ECO:0000313|Ensembl:ENSP00000393329}; Flags: Fragment;+++[H7C3M6_HUMAN|Unreviewed]SubName: Full=Protein FAM78B {ECO:0000313|Ensembl:ENSP00000412766}; Flags: Fragment;"]
[1496,"'CTNNA2'",19,7,14,13.3333333333333,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04670///Leukocyte transendothelial migration+++05213///Endometrial cancer+++04520///Adherens junction+++05200///Pathways in cancer+++05100///Bacterial invasion of epithelial cells+++05226///Gastric cancer+++04390///Hippo signaling pathway","H01890///Pattern dystrophies of the retinal pigment epithelium",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0099092///postsynaptic density, intracellular component+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0015629///actin cytoskeleton+++GO:0014069///postsynaptic density+++GO:0005912///adherens junction+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005913///cell-cell adherens junction+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0042995///cell projection+++GO:0098888///extrinsic component of presynaptic membrane+++GO:0030424///axon+++GO:0030027///lamellipodium","GO:0045296///cadherin binding+++GO:0005198///structural molecule activity+++GO:0051015///actin filament binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007409///axonogenesis+++GO:0048854///brain morphogenesis+++GO:0030154///cell differentiation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051823///regulation of synapse structural plasticity+++GO:0007275///multicellular organism development+++GO:0048813///dendrite morphogenesis+++GO:0098609///cell-cell adhesion+++GO:0098885///modification of postsynaptic actin cytoskeleton+++GO:0007010///cytoskeleton organization+++GO:0090136///epithelial cell-cell adhesion+++GO:0060134///prepulse inhibition+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion","catenin alpha 2","[CTNA2_HUMAN|Reviewed]RecName: Full=Catenin alpha-2; AltName: Full=Alpha N-catenin; AltName: Full=Alpha-catenin-related protein;+++[A0A0A0MRI5_HUMAN|Unreviewed]SubName: Full=Catenin alpha-2 {ECO:0000313|Ensembl:ENSP00000355398};+++[A0A0A0MTJ6_HUMAN|Unreviewed]SubName: Full=Catenin alpha-2 {ECO:0000313|Ensembl:ENSP00000441705};+++[B8ZZE7_HUMAN|Unreviewed]SubName: Full=Catenin alpha-2 {ECO:0000313|Ensembl:ENSP00000387232};+++[B9A010_HUMAN|Unreviewed]SubName: Full=Catenin alpha-2 {ECO:0000313|Ensembl:ENSP00000386587}; Flags: Fragment;+++[C9IZ88_HUMAN|Unreviewed]SubName: Full=Catenin alpha-2 {ECO:0000313|Ensembl:ENSP00000387073}; Flags: Fragment;+++[C9J144_HUMAN|Unreviewed]SubName: Full=Catenin alpha-2 {ECO:0000313|Ensembl:ENSP00000400105}; Flags: Fragment;+++[F6KRI5_HUMAN|Unreviewed]SubName: Full=Catenin alpha 2 isoform CTNNA2b {ECO:0000313|EMBL:AEF32484.1};+++[Q49AD3_HUMAN|Unreviewed]SubName: Full=CTNNA2 protein {ECO:0000313|EMBL:AAH40458.1};"]
[150248,"'C22orf15'",0,1,3,1.33333333333333,{"$nulls":7},"chromosome 22 open reading frame 15","[CV015_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C22orf15; AltName: Full=Protein N27C7-3;+++[A0A0G2JR07_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C22orf15 {ECO:0000313|Ensembl:ENSP00000486337}; Flags: Fragment;+++[A0A0G2JR10_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C22orf15 {ECO:0000313|Ensembl:ENSP00000486344}; Flags: Fragment;+++[A0A0G2JR24_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C22orf15 {ECO:0000313|Ensembl:ENSP00000486389}; Flags: Fragment;+++[F8W7S3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C22orf15 {ECO:0000313|Ensembl:ENSP00000305096};+++[Q14D93_HUMAN|Unreviewed]SubName: Full=Chromosome 22 open reading frame 15 {ECO:0000313|EMBL:AAI13453.2}; SubName: Full=Chromosome 22 open reading frame 15, isoform CRA_c {ECO:0000313|EMBL:EAW59601.1};"]
[150465,"'TTL'",459,334,354,382.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005623///cell","GO:0005524///ATP binding+++GO:0016874///ligase activity+++GO:0004835///tubulin-tyrosine ligase activity+++GO:0000166///nucleotide binding","GO:0000226///microtubule cytoskeleton organization+++GO:0018166///C-terminal protein-tyrosinylation+++GO:0030516///regulation of axon extension+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0006464///cellular protein modification process+++GO:0090235///regulation of metaphase plate congression","tubulin tyrosine ligase","[TTL_HUMAN|Reviewed]RecName: Full=Tubulin--tyrosine ligase; Short=TTL; EC=6.3.2.25 {ECO:0000250|UniProtKB:Q9QXJ0};"]
[151,"'ADRA2B'",111,97,207,138.333333333333,"04080///Neuroactive ligand-receptor interaction+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0016021///integral component of membrane","GO:0004938///alpha2-adrenergic receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0005515///protein binding+++GO:0004930///G protein-coupled receptor activity+++GO:0051379///epinephrine binding","GO:0007565///female pregnancy+++GO:0000187///activation of MAPK activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0019229///regulation of vasoconstriction+++GO:0032811///negative regulation of epinephrine secretion+++GO:0003056///regulation of vascular smooth muscle contraction+++GO:0030168///platelet activation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071875///adrenergic receptor signaling pathway+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0006940///regulation of smooth muscle contraction+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0045666///positive regulation of neuron differentiation+++GO:0032148///activation of protein kinase B activity+++GO:0045777///positive regulation of blood pressure+++GO:0035624///receptor transactivation+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway","adrenoceptor alpha 2B","[ADA2B_HUMAN|Reviewed]RecName: Full=Alpha-2B adrenergic receptor; AltName: Full=Alpha-2 adrenergic receptor subtype C2; AltName: Full=Alpha-2B adrenoreceptor; Short=Alpha-2B adrenoceptor; Short=Alpha-2BAR;+++[L8E8D5_HUMAN|Unreviewed]SubName: Full=Alternative protein ADRA2B {ECO:0000313|EMBL:CCQ42991.1};"]
[151230,"'KLHL23'",31,32,23,28.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0016567///protein ubiquitination","kelch like family member 23","[KLH23_HUMAN|Reviewed]RecName: Full=Kelch-like protein 23;+++[H7C0F4_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 23 {ECO:0000313|Ensembl:ENSP00000394732}; Flags: Fragment;+++[H7C1K9_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 23 {ECO:0000313|Ensembl:ENSP00000400833}; Flags: Fragment;+++[Q96AM2_HUMAN|Unreviewed]SubName: Full=KLHL23 protein {ECO:0000313|EMBL:AAH16950.1};+++[S4R3P4_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 23 {ECO:0000313|Ensembl:ENSP00000474581}; Flags: Fragment;+++[S4R452_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 23 {ECO:0000313|Ensembl:ENSP00000475081};"]
[151651,"'EFHB'",3,3,3,3,"05146///Amoebiasis+++04962///Vasopressin-regulated water reabsorption+++04014///Ras signaling pathway+++04145///Phagosome+++05152///Tuberculosis+++04144///Endocytosis+++05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0005829///cytosol+++GO:0005768///endosome+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0031901///early endosome membrane+++GO:0005769///early endosome+++GO:0010008///endosome membrane+++GO:0070062///extracellular exosome+++GO:0008021///synaptic vesicle+++GO:0036477///somatodendritic compartment+++GO:0005886///plasma membrane+++GO:0045121///membrane raft+++GO:0043679///axon terminus+++GO:0030424///axon+++GO:0030665///clathrin-coated vesicle membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0015629///actin cytoskeleton+++GO:0098559///cytoplasmic side of early endosome membrane+++GO:0030139///endocytic vesicle+++GO:0042470///melanosome+++GO:0030425///dendrite+++GO:0030670///phagocytic vesicle membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006909///phagocytosis+++GO:0045921///positive regulation of exocytosis+++GO:2000286///receptor internalization involved in canonical Wnt signaling pathway+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0030100///regulation of endocytosis+++GO:0045056///transcytosis+++GO:0036465///synaptic vesicle recycling+++GO:0061024///membrane organization+++GO:0039694///viral RNA genome replication+++GO:0051036///regulation of endosome size+++GO:0007596///blood coagulation+++GO:0045022///early endosome to late endosome transport+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0015031///protein transport+++GO:2000785///regulation of autophagosome assembly+++GO:0043687///post-translational protein modification+++GO:0006897///endocytosis+++GO:0051489///regulation of filopodium assembly","EF-hand domain family member B","[EFHB_HUMAN|Reviewed]RecName: Full=EF-hand domain-containing family member B;+++[H7C0U4_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing family member B {ECO:0000313|Ensembl:ENSP00000396778}; Flags: Fragment;+++[H9KV82_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing family member B {ECO:0000313|Ensembl:ENSP00000373908};"]
[152,"'ADRA2C'",146,101,199,148.666666666667,"04080///Neuroactive ligand-receptor interaction+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0030424///axon+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0043679///axon terminus+++GO:0099055///integral component of postsynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane","GO:0046982///protein heterodimerization activity+++GO:0004930///G protein-coupled receptor activity+++GO:0042803///protein homodimerization activity+++GO:0031694///alpha-2A adrenergic receptor binding+++GO:0051379///epinephrine binding+++GO:0004938///alpha2-adrenergic receptor activity+++GO:0004935///adrenergic receptor activity+++GO:0005515///protein binding","GO:0032811///negative regulation of epinephrine secretion+++GO:0045666///positive regulation of neuron differentiation+++GO:0010700///negative regulation of norepinephrine secretion+++GO:0043410///positive regulation of MAPK cascade+++GO:0032148///activation of protein kinase B activity+++GO:0051930///regulation of sensory perception of pain+++GO:0050796///regulation of insulin secretion+++GO:0019229///regulation of vasoconstriction+++GO:0071875///adrenergic receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007565///female pregnancy+++GO:0030168///platelet activation+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0070473///negative regulation of uterine smooth muscle contraction+++GO:0007267///cell-cell signaling+++GO:0006940///regulation of smooth muscle contraction+++GO:0007165///signal transduction+++GO:0035624///receptor transactivation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0045907///positive regulation of vasoconstriction","adrenoceptor alpha 2C","[ADA2C_HUMAN|Reviewed]RecName: Full=Alpha-2C adrenergic receptor; AltName: Full=Alpha-2 adrenergic receptor subtype C4; AltName: Full=Alpha-2C adrenoreceptor; Short=Alpha-2C adrenoceptor; Short=Alpha-2CAR;+++[D6RGL0_HUMAN|Unreviewed]SubName: Full=Alpha-2C adrenergic receptor {ECO:0000313|Ensembl:ENSP00000426268};+++[Q4W594_HUMAN|Unreviewed]SubName: Full=Adrenergic, alpha-2C-, receptor {ECO:0000313|EMBL:AAI42626.1};"]
[152518,"'NFXL1'",67,50,64,60.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II","nuclear transcription factor, X-box binding like 1","[NFXL1_HUMAN|Reviewed]RecName: Full=NF-X1-type zinc finger protein NFXL1; AltName: Full=Ovarian zinc finger protein; Short=hOZFP;+++[B1Q2B0_HUMAN|Unreviewed]SubName: Full=URCC5 {ECO:0000313|EMBL:BAG16182.1};+++[L8EBF0_HUMAN|Unreviewed]SubName: Full=Alternative protein NFXL1 {ECO:0000313|EMBL:CCQ43873.1};+++[Q8J028_HUMAN|Unreviewed]SubName: Full=Ovarian zinc finger protein {ECO:0000313|EMBL:AAN08626.1};"]
[152815,"'THAP6'",153,129,156,146,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015630///microtubule cytoskeleton","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","THAP domain containing 6","[THAP6_HUMAN|Reviewed]RecName: Full=THAP domain-containing protein 6;+++[A0A024RDF9_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_b {ECO:0000313|EMBL:EAX05735.1};+++[D6RBC3_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_e {ECO:0000313|EMBL:EAX05734.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000424255};+++[D6RC19_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000422402}; Flags: Fragment;+++[D6REL7_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426760};+++[D6REQ5_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_d {ECO:0000313|EMBL:EAX05733.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000424949};+++[D6RF27_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426698};+++[D6RFK7_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_a {ECO:0000313|EMBL:EAX05730.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426581};+++[D6RJG2_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000425646}; Flags: Fragment;"]
[153129,"'SLC38A9'",135,104,113,117.333333333333,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0071986///Ragulator complex+++GO:0005654///nucleoplasm+++GO:0031902///late endosome membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005770///late endosome+++GO:0005765///lysosomal membrane","GO:0005515///protein binding+++GO:0015171///amino acid transmembrane transporter activity","GO:0071230///cellular response to amino acid stimulus+++GO:0003333///amino acid transmembrane transport+++GO:0016241///regulation of macroautophagy+++GO:0006865///amino acid transport+++GO:0032008///positive regulation of TOR signaling+++GO:0007050///cell cycle arrest","solute carrier family 38 member 9","[S38A9_HUMAN|Reviewed]RecName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000305}; AltName: Full=Solute carrier family 38 member 9 {ECO:0000312|HGNC:HGNC:26907}; AltName: Full=Up-regulated in lung cancer 11 {ECO:0000303|Ref.2};+++[A0A024QZR9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW54927.1};+++[B3KVK8_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000397429}; SubName: Full=cDNA FLJ16675 fis, clone TKIDN2005956, weakly similar to Putative amino-acid permease F13H10.3 {ECO:0000313|EMBL:BAG53820.1};+++[D6R9Q7_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000423219}; Flags: Fragment;+++[D6R9X0_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000422843}; Flags: Fragment;+++[D6RBB9_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000424271};+++[D6RDH2_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000420950}; Flags: Fragment;+++[D6RE72_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000426925};+++[D6RER8_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000424918}; Flags: Fragment;+++[D6RG31_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000426413}; Flags: Fragment;+++[D6RHF5_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000427707};+++[D6RHW0_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000427624}; Flags: Fragment;+++[D6RIW7_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000425842}; Flags: Fragment;+++[E7ESU6_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 9 {ECO:0000313|Ensembl:ENSP00000425055}; Flags: Fragment;"]
[153733,"'CCDC112'",155,156,129,146.666666666667,{"$nulls":5},"GO:0005515///protein binding",null,"coiled-coil domain containing 112","[CC112_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 112; AltName: Full=Mutated in bladder cancer protein 1;+++[D6RF76_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 112 {ECO:0000313|Ensembl:ENSP00000424876};"]
[154075,"'SAMD3'",4,1,3,2.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0006325///chromatin organization+++GO:0030225///macrophage differentiation+++GO:0030851///granulocyte differentiation+++GO:0043249///erythrocyte maturation+++GO:0006351///transcription, DNA-templated","sterile alpha motif domain containing 3","[SAMD3_HUMAN|Reviewed]RecName: Full=Sterile alpha motif domain-containing protein 3; Short=SAM domain-containing protein 3;+++[E9PPN0_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000436997};+++[E9PR28_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000436115}; Flags: Fragment;+++[E9PR45_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000436088};+++[E9PRU9_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000434139}; Flags: Fragment;+++[E9PS85_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000435875}; Flags: Fragment;+++[H0YEH9_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000435879}; Flags: Fragment;"]
[155006,"'TMEM213'",3,3.95,2.15,3.03333333333333,"04137///Mitophagy - animal+++01100///Metabolic pathways+++05110///Vibrio cholerae infection+++00190///Oxidative phosphorylation+++04140///Autophagy - animal+++05165///Human papillomavirus infection+++05152///Tuberculosis+++05323///Rheumatoid arthritis+++04966///Collecting duct acid secretion+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04721///Synaptic vesicle cycle+++04145///Phagosome+++04142///Lysosome","H00428///Distal renal tubular acidosis (RTA type 1)+++H00436///Osteopetrosis+++H00557///Cutis laxa","M00160///V-type ATPase, eukaryotes",null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0051117///ATPase binding+++GO:0046961///proton-transporting ATPase activity, rotational mechanism","GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0006885///regulation of pH+++GO:0033572///transferrin transport+++GO:0007588///excretion+++GO:0034220///ion transmembrane transport+++GO:0015991///ATP hydrolysis coupled proton transport+++GO:1902600///proton transmembrane transport+++GO:0007035///vacuolar acidification+++GO:0007605///sensory perception of sound+++GO:0015986///ATP synthesis coupled proton transport+++GO:0001503///ossification+++GO:0008286///insulin receptor signaling pathway","transmembrane protein 213","[TM213_HUMAN|Reviewed]RecName: Full=Transmembrane protein 213; Flags: Precursor;"]
[1557,"'CYP2C19'",1,4,0,1.66666666666667,"00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse+++05204///Chemical carcinogenesis+++00590///Arachidonic acid metabolism+++00591///Linoleic acid metabolism+++01100///Metabolic pathways","H01171///Poor drug metabolism (PM)",null,"R07055///Linoleate + Oxygen + NADPH + H+ <=> 9(10)-EpOME + NADP+ + H2O+++R07046///Arachidonate + Oxygen + NADPH + H+ <=> 19(S)-HETE + NADP+ + H2O+++R07056///Linoleate + Oxygen + NADPH + H+ <=> 12(13)-EpOME + NADP+ + H2O+++R08275///Cyclophosphamide + NADPH + H+ + Oxygen <=> 4-Hydroxycyclophosphamide + NADP+ + H2O+++R08285///Ifosfamide + NADPH + H+ + Oxygen <=> 4-Hydroxyifosfamide + NADP+ + H2O+++R08343///Citalopram <=> Demethylcitalopram","GO:0043231///intracellular membrane-bounded organelle+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0008392///arachidonic acid epoxygenase activity+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0019825///oxygen binding+++GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0004497///monooxygenase activity+++GO:0019899///enzyme binding+++GO:0008395///steroid hydroxylase activity+++GO:0005506///iron ion binding","GO:0019373///epoxygenase P450 pathway+++GO:0017144///drug metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0097267///omega-hydroxylase P450 pathway+++GO:0006082///organic acid metabolic process+++GO:0008202///steroid metabolic process+++GO:0016098///monoterpenoid metabolic process+++GO:0046483///heterocycle metabolic process+++GO:0055114///oxidation-reduction process+++GO:0042738///exogenous drug catabolic process","cytochrome P450 family 2 subfamily C member 19","[CP2CJ_HUMAN|Reviewed]RecName: Full=Cytochrome P450 2C19; EC=1.14.13.-; AltName: Full=(R)-limonene 6-monooxygenase; EC=1.14.14.53 {ECO:0000269|PubMed:11950794}; AltName: Full=(S)-limonene 6-monooxygenase; EC=1.14.14.51 {ECO:0000269|PubMed:11950794}; AltName: Full=(S)-limonene 7-monooxygenase; EC=1.14.14.52 {ECO:0000269|PubMed:11950794}; AltName: Full=CYPIIC17; AltName: Full=CYPIIC19; AltName: Full=Cytochrome P450-11A; AltName: Full=Cytochrome P450-254C; AltName: Full=Mephenytoin 4-hydroxylase;+++[A0A087X125_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 2C19 {ECO:0000313|Ensembl:ENSP00000483847};+++[A0A2D1BII0_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:ATN24106.1}; Flags: Fragment;+++[A0A2D1BPP2_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:ATN24105.1}; Flags: Fragment;+++[B0ZDM8_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 family 2 subfamily C polypeptide 19 {ECO:0000313|EMBL:ABZ69068.1}; Flags: Fragment;+++[Q767A3_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 {ECO:0000313|EMBL:BAD02827.1}; Flags: Fragment;"]
[157680,"'VPS13B'",453,325,490,422.666666666667,"05016///Huntington's disease+++04714///Thermogenesis+++00190///Oxidative phosphorylation+++04137///Mitophagy - animal+++04932///Non-alcoholic fatty liver disease (NAFLD)+++00380///Tryptophan metabolism+++05012///Parkinson's disease+++01100///Metabolic pathways+++04260///Cardiac muscle contraction+++05010///Alzheimer's disease+++04140///Autophagy - animal","H00940///Cohen syndrome","M00154///Cytochrome c oxidase+++M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin","GO:0005730///nucleolus+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0010494///cytoplasmic stress granule+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005739///mitochondrion","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0004129///cytochrome-c oxidase activity+++GO:0003697///single-stranded DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding","GO:0015031///protein transport","vacuolar protein sorting 13 homolog B","[VP13B_HUMAN|Reviewed]RecName: Full=Vacuolar protein sorting-associated protein 13B; AltName: Full=Cohen syndrome protein 1;+++[H0YB72_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 13B {ECO:0000313|Ensembl:ENSP00000428809}; Flags: Fragment;+++[L8EAQ4_HUMAN|Unreviewed]SubName: Full=Alternative protein VPS13B {ECO:0000313|EMBL:CCQ43856.1};+++[Q8N509_HUMAN|Unreviewed]SubName: Full=VPS13B protein {ECO:0000313|EMBL:AAH33121.2}; Flags: Fragment;+++[Q8WW67_HUMAN|Unreviewed]SubName: Full=VPS13B protein {ECO:0000313|EMBL:AAH20813.1}; Flags: Fragment;"]
[158046,"'NXNL2'",4,7,5,5.33333333333333,{"$nulls":4},"GO:0005737///cytoplasm","GO:0004791///thioredoxin-disulfide reductase activity","GO:0045494///photoreceptor cell maintenance+++GO:0007600///sensory perception+++GO:0007608///sensory perception of smell+++GO:0007601///visual perception","nucleoredoxin like 2","[NXNL2_HUMAN|Reviewed]RecName: Full=Nucleoredoxin-like protein 2; AltName: Full=Rod-derived cone viability factor 2; Short=RdCVF2;+++[A0A087WXA5_HUMAN|Unreviewed]SubName: Full=Nucleoredoxin-like protein 2 {ECO:0000313|Ensembl:ENSP00000480855};"]
[158471,"'PRUNE2'",772,694,546,670.666666666667,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis",null,"M00056///O-glycan biosynthesis, mucin type core","R05910///UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00031+++R05912///UDP-N-acetyl-D-glucosamine + T antigen <=> UDP + G00025","GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016462///pyrophosphatase activity+++GO:0004309///exopolyphosphatase activity+++GO:0046872///metal ion binding","GO:0006915///apoptotic process+++GO:0006798///polyphosphate catabolic process","prune homolog 2","[PRUN2_HUMAN|Reviewed]RecName: Full=Protein prune homolog 2; AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1;+++[A0A024R220_HUMAN|Unreviewed]SubName: Full=KIAA0367, isoform CRA_b {ECO:0000313|EMBL:EAW62587.1};+++[A0A088AWP5_HUMAN|Unreviewed]SubName: Full=Protein prune homolog 2 {ECO:0000313|Ensembl:ENSP00000393843};+++[A0A0C4DFM3_HUMAN|Unreviewed]SubName: Full=Protein prune homolog 2 {ECO:0000313|Ensembl:ENSP00000223609};+++[B4DJW7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59118 {ECO:0000313|EMBL:BAG58979.1};+++[B4DSQ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54876 {ECO:0000313|EMBL:BAG61715.1};+++[B9EK61_HUMAN|Unreviewed]SubName: Full=PRUNE2 protein {ECO:0000313|EMBL:AAI50642.1};+++[D6RTK6_HUMAN|Unreviewed]SubName: Full=Prune homolog 2 {ECO:0000313|EMBL:BAJ08045.1};+++[E9PDC2_HUMAN|Unreviewed]SubName: Full=Protein prune homolog 2 {ECO:0000313|Ensembl:ENSP00000397425};+++[G8XWS8_HUMAN|Unreviewed]SubName: Full=PRUNE2 {ECO:0000313|EMBL:ACY78253.1};+++[G8XWS9_HUMAN|Unreviewed]SubName: Full=Truncated PRUNE2 {ECO:0000313|EMBL:ACY78254.1};+++[H7BZH9_HUMAN|Unreviewed]SubName: Full=Protein prune homolog 2 {ECO:0000313|Ensembl:ENSP00000389706}; Flags: Fragment;+++[L8E865_HUMAN|Unreviewed]SubName: Full=Alternative protein PRUNE2 {ECO:0000313|EMBL:CCQ43495.1};+++[Q5JUB8_HUMAN|Unreviewed]SubName: Full=Protein prune homolog 2 {ECO:0000313|Ensembl:ENSP00000365907};+++[Q5JUB9_HUMAN|Unreviewed]SubName: Full=Protein prune homolog 2 {ECO:0000313|Ensembl:ENSP00000393657}; Flags: Fragment;+++[X6R9J3_HUMAN|Unreviewed]SubName: Full=Protein prune homolog 2 {ECO:0000313|Ensembl:ENSP00000365903};"]
[1591,"'CYP24A1'",540,466,416,474,"00100///Steroid biosynthesis+++04928///Parathyroid hormone synthesis, secretion and action+++01100///Metabolic pathways+++05206///MicroRNAs in cancer","H01371///Hypercalcemia infantile",null,"R09516///calcidiol,adrenodoxin:oxygen oxidoreductase (24-hydroxylating)   Calcidiol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Secalciferol + 2 Oxidized adrenal ferredoxin + H2O+++R09515///calcitriol,adrenodoxin:oxygen oxidoreductase (24-hydroxylating)   Calcitriol + 2 Reduced adrenal ferredoxin + 2 H+ + Oxygen <=> Calcitetrol + 2 Oxidized adrenal ferredoxin + H2O","GO:0005634///nucleus+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion","GO:0016491///oxidoreductase activity+++GO:0005506///iron ion binding+++GO:0030342///1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity+++GO:0020037///heme binding+++GO:0004497///monooxygenase activity+++GO:0008403///25-hydroxycholecalciferol-24-hydroxylase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0046872///metal ion binding","GO:0001649///osteoblast differentiation+++GO:0042369///vitamin D catabolic process+++GO:0070561///vitamin D receptor signaling pathway+++GO:0006766///vitamin metabolic process+++GO:0055114///oxidation-reduction process+++GO:0042359///vitamin D metabolic process+++GO:0033280///response to vitamin D","cytochrome P450 family 24 subfamily A member 1","[CP24A_HUMAN|Reviewed]RecName: Full=1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Short=24-OHase; Short=Vitamin D(3) 24-hydroxylase; EC=1.14.15.16 {ECO:0000269|PubMed:15574355}; AltName: Full=Cytochrome P450 24A1; AltName: Full=Cytochrome P450-CC24; Flags: Precursor;"]
[160335,"'TMTC2'",97,76,82,85,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0055074///calcium ion homeostasis","transmembrane and tetratricopeptide repeat containing 2","[TMTC2_HUMAN|Reviewed]RecName: Full=Transmembrane and TPR repeat-containing protein 2;+++[A0A0B4J253_HUMAN|Unreviewed]SubName: Full=Transmembrane and TPR repeat-containing protein 2 {ECO:0000313|Ensembl:ENSP00000447609}; SubName: Full=Transmembrane and tetratricopeptide repeat containing 2, isoform CRA_b {ECO:0000313|EMBL:EAW97385.1};+++[B7Z639_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54938, weakly similar to Mus musculus transmembrane and tetratricopeptide repeat containing 1 (Tmtc1), mRNA {ECO:0000313|EMBL:BAH13125.1};+++[F8VRQ2_HUMAN|Unreviewed]SubName: Full=Transmembrane and TPR repeat-containing protein 2 {ECO:0000313|Ensembl:ENSP00000448630};+++[F8VSH2_HUMAN|Unreviewed]SubName: Full=Transmembrane and TPR repeat-containing protein 2 {ECO:0000313|Ensembl:ENSP00000448292};"]
[160857,"'CCDC122'",14.71,28.9,24.36,22.6566666666667,{"$nulls":4},"GO:0098978///glutamatergic synapse+++GO:1990904///ribonucleoprotein complex+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0010494///cytoplasmic stress granule+++GO:0005634///nucleus+++GO:0005777///peroxisome+++GO:0016607///nuclear speck+++GO:0005730///nucleolus","GO:0000166///nucleotide binding+++GO:0005507///copper ion binding+++GO:0016301///kinase activity+++GO:0003727///single-stranded RNA binding+++GO:0004143///diacylglycerol kinase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0001727///lipid kinase activity+++GO:0046872///metal ion binding+++GO:0003951///NAD+ kinase activity+++GO:0003697///single-stranded DNA binding+++GO:0008022///protein C-terminus binding","GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0030168///platelet activation+++GO:0016477///cell migration+++GO:0032197///transposition, RNA-mediated+++GO:0046486///glycerolipid metabolic process+++GO:0046339///diacylglycerol metabolic process+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0035556///intracellular signal transduction+++GO:0046834///lipid phosphorylation","coiled-coil domain containing 122","[CC122_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 122;+++[A0A087WWN1_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 122 {ECO:0000313|Ensembl:ENSP00000480362}; Flags: Fragment;+++[B7ZMJ0_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 122 {ECO:0000313|EMBL:AAI44572.1};"]
[161424,"'NOP9'",943,852,923,906,"04080///Neuroactive ligand-receptor interaction+++04020///Calcium signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm","GO:0008528///G protein-coupled peptide receptor activity+++GO:0003723///RNA binding+++GO:0004974///leukotriene receptor activity+++GO:0001632///leukotriene B4 receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006935///chemotaxis+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0051546///keratinocyte migration","NOP9 nucleolar protein","[NOP9_HUMAN|Reviewed]RecName: Full=Nucleolar protein 9;+++[H0YJP7_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 9 {ECO:0000313|Ensembl:ENSP00000451905}; Flags: Fragment;"]
[162,"'AP1B1'",3817,3707,3736,3753.33333333333,"04142///Lysosome",{"$nulls":3},"GO:0032588///trans-Golgi network membrane+++GO:0005829///cytosol+++GO:0005765///lysosomal membrane+++GO:0031410///cytoplasmic vesicle+++GO:0030117///membrane coat+++GO:0043231///intracellular membrane-bounded organelle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0030131///clathrin adaptor complex+++GO:0000139///Golgi membrane","GO:0005215///transporter activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030276///clathrin binding","GO:0007507///heart development+++GO:0015031///protein transport+++GO:0050690///regulation of defense response to virus by virus+++GO:0016192///vesicle-mediated transport+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0007368///determination of left/right symmetry+++GO:0006886///intracellular protein transport","adaptor related protein complex 1 subunit beta 1","[AP1B1_HUMAN|Reviewed]RecName: Full=AP-1 complex subunit beta-1; AltName: Full=Adaptor protein complex AP-1 subunit beta-1; AltName: Full=Adaptor-related protein complex 1 subunit beta-1; AltName: Full=Beta-1-adaptin; AltName: Full=Beta-adaptin 1; AltName: Full=Clathrin assembly protein complex 1 beta large chain; AltName: Full=Golgi adaptor HA1/AP1 adaptin beta subunit;+++[C9J1E7_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit beta-1 {ECO:0000313|Ensembl:ENSP00000400022}; Flags: Fragment;+++[H7C034_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit beta-1 {ECO:0000313|Ensembl:ENSP00000392735}; Flags: Fragment;"]
[1627,"'DBN1'",12270,12751,10858,11959.6666666667,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0099524///postsynaptic cytosol+++GO:0016020///membrane+++GO:0014069///postsynaptic density+++GO:0005921///gap junction+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005856///cytoskeleton+++GO:0005911///cell-cell junction+++GO:0042995///cell projection+++GO:0030425///dendrite+++GO:0030426///growth cone+++GO:0005938///cell cortex+++GO:0042641///actomyosin+++GO:0045211///postsynaptic membrane+++GO:0030863///cortical cytoskeleton+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0045296///cadherin binding+++GO:0005522///profilin binding+++GO:0003779///actin binding+++GO:0005515///protein binding","GO:0007399///nervous system development+++GO:0010643///cell communication by chemical coupling+++GO:0010644///cell communication by electrical coupling+++GO:1902685///positive regulation of receptor localization to synapse+++GO:0051220///cytoplasmic sequestering of protein+++GO:0030154///cell differentiation+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:0048699///generation of neurons+++GO:0031915///positive regulation of synaptic plasticity+++GO:0050773///regulation of dendrite development+++GO:0032507///maintenance of protein location in cell+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0007015///actin filament organization+++GO:0007275///multicellular organism development+++GO:0061351///neural precursor cell proliferation","drebrin 1","[DREB_HUMAN|Reviewed]RecName: Full=Drebrin; AltName: Full=Developmentally-regulated brain protein;+++[A0A2Z6ATB6_HUMAN|Unreviewed]SubName: Full=Drebrin A {ECO:0000313|EMBL:BBD06306.1};+++[B3KSQ7_HUMAN|Unreviewed]SubName: Full=Drebrin 1, isoform CRA_d {ECO:0000313|EMBL:EAW84992.1}; SubName: Full=cDNA FLJ36806 fis, clone ASTRO1000165, highly similar to Drebrin {ECO:0000313|EMBL:BAG52819.1};+++[D6R9Q9_HUMAN|Unreviewed]SubName: Full=Drebrin {ECO:0000313|Ensembl:ENSP00000423208};+++[D6R9W4_HUMAN|Unreviewed]SubName: Full=Drebrin {ECO:0000313|Ensembl:ENSP00000422854}; Flags: Fragment;+++[D6RCR4_HUMAN|Unreviewed]SubName: Full=Drebrin {ECO:0000313|Ensembl:ENSP00000425546}; Flags: Fragment;+++[D6RFI1_HUMAN|Unreviewed]SubName: Full=Drebrin {ECO:0000313|Ensembl:ENSP00000421465}; Flags: Fragment;"]
[163049,"'ZNF791'",322,311.91,313.01,315.64,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 791","[ZN791_HUMAN|Reviewed]RecName: Full=Zinc finger protein 791;+++[C9JU55_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 791 {ECO:0000313|Ensembl:ENSP00000412981};+++[M0QYQ0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 791 {ECO:0000313|Ensembl:ENSP00000469996};+++[M0R0E8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 791 {ECO:0000313|Ensembl:ENSP00000471179}; Flags: Fragment;+++[M0R2N1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 791 {ECO:0000313|Ensembl:ENSP00000472685};"]
[163051,"'ZNF709'",23.01,19,17,19.67,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 709","[ZN709_HUMAN|Reviewed]RecName: Full=Zinc finger protein 709;+++[H7C129_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 709 {ECO:0000313|Ensembl:ENSP00000398085}; Flags: Fragment;"]
[163859,"'SDE2'",89.08,90,84,87.6933333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003684///damaged DNA binding","GO:0016485///protein processing+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0034644///cellular response to UV+++GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0071156///regulation of cell cycle arrest","SDE2 telomere maintenance homolog","[SDE2_HUMAN|Reviewed]RecName: Full=Replication stress response regulator SDE2 {ECO:0000305}; Flags: Precursor;"]
[163933,"'FAM43B'",3,12,12,9,{"$nulls":7},"family with sequence similarity 43 member B","[FA43B_HUMAN|Reviewed]RecName: Full=Protein FAM43B;"]
[165186,"'TOGARAM2'",25,45,100,56.6666666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0001650///fibrillar center","GO:0003723///RNA binding","GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0006364///rRNA processing+++GO:0006351///transcription, DNA-templated+++GO:2000234///positive regulation of rRNA processing","TOG array regulator of axonemal microtubules 2","[TGRM2_HUMAN|Reviewed]RecName: Full=TOG array regulator of axonemal microtubules protein 2 {ECO:0000312|HGNC:HGNC:33715}; AltName: Full=Crescerin-2 {ECO:0000305};+++[B4DLF7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60294 {ECO:0000313|EMBL:BAG59519.1};+++[B5MCN5_HUMAN|Unreviewed]SubName: Full=TOG array regulator of axonemal microtubules protein 2 {ECO:0000313|Ensembl:ENSP00000384897}; Flags: Fragment;+++[C9JJW1_HUMAN|Unreviewed]SubName: Full=TOG array regulator of axonemal microtubules protein 2 {ECO:0000313|Ensembl:ENSP00000396739}; Flags: Fragment;+++[C9JLI7_HUMAN|Unreviewed]SubName: Full=TOG array regulator of axonemal microtubules protein 2 {ECO:0000313|Ensembl:ENSP00000402415}; Flags: Fragment;"]
[165324,"'UBXN2A'",142,151,135,142.666666666667,{"$nulls":4},"GO:0005801///cis-Golgi network+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0043130///ubiquitin binding+++GO:0033130///acetylcholine receptor binding","GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0010468///regulation of gene expression+++GO:0031468///nuclear envelope reassembly+++GO:0007030///Golgi organization+++GO:0042176///regulation of protein catabolic process+++GO:0031396///regulation of protein ubiquitination+++GO:0000045///autophagosome assembly+++GO:0061025///membrane fusion+++GO:1990830///cellular response to leukemia inhibitory factor","UBX domain protein 2A","[UBX2A_HUMAN|Reviewed]RecName: Full=UBX domain-containing protein 2A; AltName: Full=UBX domain-containing protein 4;"]
[1660,"'DHX9'",1655,1408,1444,1502.33333333333,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:1990904///ribonucleoprotein complex+++GO:0070578///RISC-loading complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0035068///micro-ribonucleoprotein complex+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0015629///actin cytoskeleton+++GO:0005844///polysome+++GO:0005654///nucleoplasm+++GO:0042788///polysomal ribosome+++GO:0005726///perichromatin fibrils+++GO:0005730///nucleolus+++GO:0097165///nuclear stress granule","GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0000166///nucleotide binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0035613///RNA stem-loop binding+++GO:0000993///RNA polymerase II complex binding+++GO:0003676///nucleic acid binding+++GO:0003727///single-stranded RNA binding+++GO:0070063///RNA polymerase binding+++GO:0061676///importin-alpha family protein binding+++GO:0003713///transcription coactivator activity+++GO:0003697///single-stranded DNA binding+++GO:0003729///mRNA binding+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0003725///double-stranded RNA binding+++GO:0003724///RNA helicase activity+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0031490///chromatin DNA binding+++GO:0035197///siRNA binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0003688///DNA replication origin binding+++GO:0045142///triplex DNA binding+++GO:0005515///protein binding+++GO:0001069///regulatory region RNA binding+++GO:1990825///sequence-specific mRNA binding+++GO:1905538///polysome binding+++GO:0016887///ATPase activity+++GO:0017111///nucleoside-triphosphatase activity+++GO:1990841///promoter-specific chromatin binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0043140///ATP-dependent 3'-5' DNA helicase activity+++GO:1905172///RISC complex binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0003723///RNA binding+++GO:1990518///single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity+++GO:0003690///double-stranded DNA binding+++GO:0033681///ATP-dependent 3'-5' DNA/RNA helicase activity+++GO:0003712///transcription coregulator activity+++GO:0003677///DNA binding","GO:0045739///positive regulation of DNA repair+++GO:2000767///positive regulation of cytoplasmic translation+++GO:0006954///inflammatory response+++GO:0071360///cellular response to exogenous dsRNA+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0010501///RNA secondary structure unwinding+++GO:0044806///G-quadruplex DNA unwinding+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071356///cellular response to tumor necrosis factor+++GO:2000637///positive regulation of gene silencing by miRNA+++GO:1903608///protein localization to cytoplasmic stress granule+++GO:1902741///positive regulation of interferon-alpha secretion+++GO:0031047///gene silencing by RNA+++GO:2000765///regulation of cytoplasmic translation+++GO:1904973///positive regulation of viral translation+++GO:2000373///positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity+++GO:0032481///positive regulation of type I interferon production+++GO:0035549///positive regulation of interferon-beta secretion+++GO:0030423///targeting of mRNA for destruction involved in RNA interference+++GO:0002376///immune system process+++GO:0070922///small RNA loading onto RISC+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0050434///positive regulation of viral transcription+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0032741///positive regulation of interleukin-18 production+++GO:0051028///mRNA transport+++GO:0001649///osteoblast differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0045089///positive regulation of innate immune response+++GO:0006260///DNA replication+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0045740///positive regulation of DNA replication+++GO:0006417///regulation of translation+++GO:0050684///regulation of mRNA processing+++GO:0008380///RNA splicing+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0050691///regulation of defense response to virus by host+++GO:0048511///rhythmic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:1904469///positive regulation of tumor necrosis factor secretion+++GO:1905698///positive regulation of polysome binding+++GO:0045087///innate immune response+++GO:0070269///pyroptosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032508///DNA duplex unwinding+++GO:0006353///DNA-templated transcription, termination+++GO:2000778///positive regulation of interleukin-6 secretion+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0039695///DNA-templated viral transcription","DExH-box helicase 9","[DHX9_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase A {ECO:0000305}; EC=3.6.4.13 {ECO:0000269|PubMed:11416126, ECO:0000269|PubMed:1537828, ECO:0000269|PubMed:20510246, ECO:0000269|PubMed:20669935, ECO:0000269|PubMed:24049074, ECO:0000269|PubMed:25062910, ECO:0000269|PubMed:8690889}; AltName: Full=DEAH box protein 9; AltName: Full=DExH-box helicase 9 {ECO:0000312|HGNC:HGNC:2750}; AltName: Full=Leukophysin {ECO:0000303|PubMed:8690889}; Short=LKP {ECO:0000303|PubMed:8690889}; AltName: Full=Nuclear DNA helicase II {ECO:0000303|PubMed:1537828, ECO:0000303|PubMed:8344961, ECO:0000303|PubMed:9111062}; Short=NDH II {ECO:0000303|PubMed:8344961, ECO:0000303|PubMed:9111062}; AltName: Full=RNA helicase A {ECO:0000303|PubMed:9111062};+++[B3KU66_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39263 fis, clone OCBBF2009571, highly similar to ATP-dependent RNA helicase A {ECO:0000313|EMBL:BAG53328.1};+++[Q58F26_HUMAN|Unreviewed]SubName: Full=DHX9 protein {ECO:0000313|EMBL:AAH08773.1}; Flags: Fragment;+++[Q6PJK6_HUMAN|Unreviewed]SubName: Full=DHX9 protein {ECO:0000313|EMBL:AAH14246.1}; Flags: Fragment;"]
[167153,"'TENT2'",341,298,290,309.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0031380///nuclear RNA-directed RNA polymerase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0034062///5'-3' RNA polymerase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0070566///adenylyltransferase activity+++GO:0016740///transferase activity+++GO:0004652///polynucleotide adenylyltransferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0030182///neuron differentiation+++GO:0071044///histone mRNA catabolic process+++GO:0021766///hippocampus development+++GO:1990603///dark adaptation+++GO:0006397///mRNA processing+++GO:0060041///retina development in camera-type eye+++GO:2000626///negative regulation of miRNA catabolic process+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0043631///RNA polyadenylation+++GO:0043489///RNA stabilization","terminal nucleotidyltransferase 2","[GLD2_HUMAN|Reviewed]RecName: Full=Poly(A) RNA polymerase GLD2 {ECO:0000305}; Short=hGLD-2 {ECO:0000305}; EC=2.7.7.19 {ECO:0000269|PubMed:15070731, ECO:0000269|PubMed:23200856}; AltName: Full=PAP-associated domain-containing protein 4; AltName: Full=Terminal nucleotidyltransferase 2 {ECO:0000312|HGNC:HGNC:26776}; AltName: Full=Terminal uridylyltransferase 2; Short=TUTase 2;+++[D6RAF2_HUMAN|Unreviewed]SubName: Full=Poly(A) RNA polymerase GLD2 {ECO:0000313|Ensembl:ENSP00000421966};"]
[1677,"'DFFB'",36.88,38.99,43,39.6233333333333,"04210///Apoptosis",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0004536///deoxyribonuclease activity+++GO:0042802///identical protein binding+++GO:0019904///protein domain specific binding+++GO:0019899///enzyme binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004518///nuclease activity+++GO:0097718///disordered domain specific binding","GO:0006915///apoptotic process+++GO:0051260///protein homooligomerization+++GO:0030263///apoptotic chromosome condensation+++GO:0006309///apoptotic DNA fragmentation+++GO:0006308///DNA catabolic process","DNA fragmentation factor subunit beta","[DFFB_HUMAN|Reviewed]RecName: Full=DNA fragmentation factor subunit beta; EC=3.-.-.-; AltName: Full=Caspase-activated deoxyribonuclease; Short=CAD; Short=Caspase-activated DNase; AltName: Full=Caspase-activated nuclease; Short=CPAN; AltName: Full=DNA fragmentation factor 40 kDa subunit; Short=DFF-40;+++[A0A024R4C8_HUMAN|Unreviewed]SubName: Full=DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase), isoform CRA_b {ECO:0000313|EMBL:EAW71487.1};+++[A0A0B4J1S5_HUMAN|Unreviewed]SubName: Full=DNA fragmentation factor subunit beta {ECO:0000313|Ensembl:ENSP00000345906};+++[B4DZS0_HUMAN|Unreviewed]SubName: Full=DNA fragmentation factor subunit beta {ECO:0000313|Ensembl:ENSP00000339524}; SubName: Full=cDNA FLJ50316, highly similar to DNAation factor subunit beta {ECO:0000313|EMBL:BAG64182.1};+++[G3XAD0_HUMAN|Unreviewed]SubName: Full=DNA fragmentation factor subunit beta {ECO:0000313|Ensembl:ENSP00000462175}; SubName: Full=DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase), isoform CRA_a {ECO:0000313|EMBL:EAW71485.1};+++[J3KT26_HUMAN|Unreviewed]SubName: Full=DNA fragmentation factor subunit beta {ECO:0000313|Ensembl:ENSP00000462770}; Flags: Fragment;+++[Q96P72_HUMAN|Unreviewed]SubName: Full=DNA fragmentation factor subunit beta {ECO:0000313|Ensembl:ENSP00000367448}; SubName: Full=DNAation factor B truncated form III {ECO:0000313|EMBL:AAL02007.1};+++[Q96P73_HUMAN|Unreviewed]SubName: Full=DFFB protein {ECO:0000313|EMBL:AAH32827.1}; SubName: Full=DNA fragmentation factor subunit beta {ECO:0000313|Ensembl:ENSP00000463688}; SubName: Full=DNAation factor B truncated form II {ECO:0000313|EMBL:AAL02006.1}; SubName: Full=DNAation factor, 40kDa, beta polypeptide (Caspase-activated DNase), isoform CRA_d {ECO:0000313|EMBL:EAW71489.1};+++[Q96P74_HUMAN|Unreviewed]SubName: Full=DNAation factor B truncated form I {ECO:0000313|EMBL:AAL02005.1};"]
[169522,"'KCNV2'",0,1,2,1,null,"H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0008076///voltage-gated potassium channel complex","GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity","GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0006813///potassium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0051260///protein homooligomerization+++GO:0055085///transmembrane transport","potassium voltage-gated channel modifier subfamily V member 2","[KCNV2_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily V member 2; AltName: Full=Voltage-gated potassium channel subunit Kv8.2;"]
[170302,"'ARX'",0,1,0,0.333333333333333,null,"H00606///Early infantile epileptic encephalopathy+++H01920///Partington syndrome+++H00658///Syndromic X-linked mental retardation+++H01460///West syndrome+++H00268///Lissencephaly (LIS)+++H00480///Non-syndromic X-linked mental retardation+++H01919///Proud syndrome",null,null,"GO:0005634///nucleus","GO:0001206///distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0007411///axon guidance+++GO:0044241///lipid digestion+++GO:0010628///positive regulation of gene expression+++GO:0021831///embryonic olfactory bulb interneuron precursor migration+++GO:0021759///globus pallidus development+++GO:0006351///transcription, DNA-templated+++GO:0046622///positive regulation of organ growth+++GO:0042127///regulation of cell proliferation+++GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0072148///epithelial cell fate commitment+++GO:0021846///cell proliferation in forebrain+++GO:0021800///cerebral cortex tangential migration","aristaless related homeobox","[ARX_HUMAN|Reviewed]RecName: Full=Homeobox protein ARX; AltName: Full=Aristaless-related homeobox;+++[A0A1B0GUI3_HUMAN|Unreviewed]SubName: Full=Homeobox protein ARX {ECO:0000313|Ensembl:ENSP00000490122}; Flags: Fragment;"]
[171017,"'ZNF384'",1296,1239,1122,1219,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development","zinc finger protein 384","[ZN384_HUMAN|Reviewed]RecName: Full=Zinc finger protein 384; AltName: Full=CAG repeat protein 1; AltName: Full=CAS-interacting zinc finger protein; AltName: Full=Nuclear matrix transcription factor 4; Short=Nuclear matrix protein 4; AltName: Full=Trinucleotide repeat-containing gene 1 protein;+++[D3DUR9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384, isoform CRA_a {ECO:0000313|EMBL:EAW88757.1};+++[E9PHB3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000399572}; Flags: Fragment;+++[F5GYZ1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000441408}; Flags: Fragment;+++[F5H0D6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000438047}; Flags: Fragment;+++[F5H105_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000439736}; Flags: Fragment;+++[F5H3Z9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000438555}; Flags: Fragment;+++[F5H6N8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000437488}; Flags: Fragment;+++[F5H8L7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000412911}; Flags: Fragment;+++[O15420_HUMAN|Unreviewed]SubName: Full=CAGH1 alternate open reading frame {ECO:0000313|EMBL:AAB91451.1}; SubName: Full=HCG21634 {ECO:0000313|EMBL:EAW88761.1}; SubName: Full=cDNA FLJ59043 {ECO:0000313|EMBL:BAG60923.1};+++[R4GMR4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 384 {ECO:0000313|Ensembl:ENSP00000473311}; Flags: Fragment;"]
[171483,"'FAM9B'",1,0,0,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0000795///synaptonemal complex+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0051321///meiotic cell cycle+++GO:0007286///spermatid development+++GO:0007283///spermatogenesis","family with sequence similarity 9 member B","[FAM9B_HUMAN|Reviewed]RecName: Full=Protein FAM9B;+++[A0A024RBV3_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 9, member B, isoform CRA_c {ECO:0000313|EMBL:EAW98766.1};+++[E9PL73_HUMAN|Unreviewed]SubName: Full=Protein FAM9B {ECO:0000313|Ensembl:ENSP00000431456};"]
[1743,"'DLST'",1354,1269,1353,1325.33333333333,"01120///Microbial metabolism in diverse environments+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++00020///Citrate cycle (TCA cycle)+++01110///Biosynthesis of secondary metabolites+++01200///Carbon metabolism+++00310///Lysine degradation",null,"M00032///Lysine degradation, lysine => saccharopine => acetoacetyl-CoA+++M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00011///Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate","R08549///2-Oxoglutarate dehydrogenase complex   2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H++++R02570///succinyl-CoA:enzyme N6-(dihydrolipoyl)lysine S-succinyltransferase   Succinyl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine+++R02571///Glutaryl-CoA:dihydrolipoamide S-succinyltransferase   Glutaryl-CoA + Enzyme N6-(dihydrolipoyl)lysine <=> CoA + [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine","GO:0045252///oxoglutarate dehydrogenase complex+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0043209///myelin sheath+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0004149///dihydrolipoyllysine-residue succinyltransferase activity+++GO:0005515///protein binding","GO:0006103///2-oxoglutarate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine+++GO:0006091///generation of precursor metabolites and energy+++GO:0106077///histone succinylation+++GO:0006104///succinyl-CoA metabolic process","dihydrolipoamide S-succinyltransferase","[ODO2_HUMAN|Reviewed]RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; EC=2.3.1.61 {ECO:0000250|UniProtKB:Q9N0F1}; AltName: Full=2-oxoglutarate dehydrogenase complex component E2; Short=OGDC-E2; AltName: Full=Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; AltName: Full=E2K; Flags: Precursor;+++[A0A024R6C9_HUMAN|Unreviewed]SubName: Full=Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex), isoform CRA_a {ECO:0000313|EMBL:EAW81202.1};+++[B7Z6J1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55035, highly similar to Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|EMBL:BAH13277.1};+++[B7ZAZ8_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|Ensembl:ENSP00000238671}; SubName: Full=cDNA, FLJ79362, moderately similar to Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|EMBL:BAH14834.1};+++[G3V3F0_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|Ensembl:ENSP00000451210};+++[G3V498_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|Ensembl:ENSP00000451670};+++[G3V5L9_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|Ensembl:ENSP00000452417};+++[G3V5M3_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|Ensembl:ENSP00000452422};+++[H0YJF9_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000313|Ensembl:ENSP00000451425}; Flags: Fragment;+++[Q6IBS5_HUMAN|Unreviewed]SubName: Full=DLST protein {ECO:0000313|EMBL:CAG33008.1};+++[Q86SW4_HUMAN|Unreviewed]RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423}; EC=2.3.1.- {ECO:0000256|RuleBase:RU003423}; Flags: Fragment;+++[Q86TQ8_HUMAN|Unreviewed]RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423}; EC=2.3.1.- {ECO:0000256|RuleBase:RU003423}; Flags: Fragment;+++[Q86TW7_HUMAN|Unreviewed]RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423}; EC=2.3.1.- {ECO:0000256|RuleBase:RU003423}; Flags: Fragment;"]
[1756,"'DMD'",873,634,837,781.333333333333,"05410///Hypertrophic cardiomyopathy (HCM)+++05416///Viral myocarditis+++05414///Dilated cardiomyopathy (DCM)+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)","H01964///Becker muscular dystrophy+++H00294///Dilated cardiomyopathy (DCM)+++H00562///Dystrophinopathies+++H00552///Chromosome Xp21 deletion syndrome+++H01963///Duchenne muscular dystrophy (DMD)",null,null,"GO:0005794///Golgi apparatus+++GO:0030424///axon+++GO:0043025///neuronal cell body+++GO:0043034///costamere+++GO:0030018///Z disc+++GO:0005886///plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0030141///secretory granule+++GO:0031527///filopodium membrane+++GO:0099617///matrix side of mitochondrial inner membrane+++GO:0030175///filopodium+++GO:0015629///actin cytoskeleton+++GO:0044306///neuron projection terminus+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0030055///cell-substrate junction+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0016013///syntrophin complex+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0097449///astrocyte projection+++GO:0005856///cytoskeleton+++GO:0045211///postsynaptic membrane+++GO:0042383///sarcolemma+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0045121///membrane raft+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0005840///ribosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005883///neurofilament+++GO:0032991///protein-containing complex+++GO:0014069///postsynaptic density+++GO:0042995///cell projection+++GO:0030016///myofibril+++GO:0045202///synapse+++GO:0009986///cell surface+++GO:0005634///nucleus","GO:0017022///myosin binding+++GO:0005521///lamin binding+++GO:0044877///protein-containing complex binding+++GO:0002162///dystroglycan binding+++GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0017166///vinculin binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005178///integrin binding+++GO:0030165///PDZ domain binding+++GO:0050998///nitric-oxide synthase binding+++GO:0008307///structural constituent of muscle","GO:0086001///cardiac muscle cell action potential+++GO:0060857///establishment of glial blood-brain barrier+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0051726///regulation of cell cycle+++GO:0090287///regulation of cellular response to growth factor stimulus+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:0034622///cellular protein-containing complex assembly+++GO:0043403///skeletal muscle tissue regeneration+++GO:0060048///cardiac muscle contraction+++GO:0045665///negative regulation of neuron differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0051647///nucleus localization+++GO:0021629///olfactory nerve structural organization+++GO:0048747///muscle fiber development+++GO:0007519///skeletal muscle tissue development+++GO:0042391///regulation of membrane potential+++GO:0014904///myotube cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:2000651///positive regulation of sodium ion transmembrane transporter activity+++GO:0014819///regulation of skeletal muscle contraction+++GO:0021987///cerebral cortex development+++GO:0043043///peptide biosynthetic process+++GO:0045666///positive regulation of neuron differentiation+++GO:0035994///response to muscle stretch+++GO:0046716///muscle cell cellular homeostasis+++GO:0030154///cell differentiation+++GO:0010976///positive regulation of neuron projection development+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression+++GO:0007568///aging+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0009414///response to water deprivation+++GO:0044458///motile cilium assembly+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0030182///neuron differentiation+++GO:0007517///muscle organ development+++GO:0045213///neurotransmitter receptor metabolic process+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0008065///establishment of blood-nerve barrier+++GO:0014809///regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0034613///cellular protein localization+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0042692///muscle cell differentiation+++GO:0007010///cytoskeleton organization+++GO:0030049///muscle filament sliding+++GO:0002027///regulation of heart rate","dystrophin","[DMD_HUMAN|Reviewed]RecName: Full=Dystrophin;+++[A0A075B6G3_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000354923};+++[A0A087WTU7_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000478150};+++[A0A087WV90_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000479270};+++[A0A0B4J1W6_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000388559}; Flags: Fragment;+++[A0A0C4DH61_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000417075}; Flags: Fragment;+++[A0A0S2Z3B2_HUMAN|Unreviewed]SubName: Full=Dystrophin isoform 5 {ECO:0000313|EMBL:ALQ33491.1};+++[A0A0S2Z3B5_HUMAN|Unreviewed]SubName: Full=Dystrophin isoform 2 {ECO:0000313|EMBL:ALQ33489.1};+++[A0A0S2Z3J7_HUMAN|Unreviewed]SubName: Full=Dystrophin isoform 1 {ECO:0000313|EMBL:ALQ33488.1}; Flags: Fragment;+++[A0A0S2Z3M6_HUMAN|Unreviewed]SubName: Full=Dystrophin isoform 6 {ECO:0000313|EMBL:ALQ33492.1}; Flags: Fragment;+++[A1L0U9_HUMAN|Unreviewed]SubName: Full=DMD protein {ECO:0000313|EMBL:AAI27104.2};+++[A7E212_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAI50142.1};+++[B4DSV7_HUMAN|Unreviewed]SubName: Full=Dystrophin isoform 4 {ECO:0000313|EMBL:ALQ33490.1}; SubName: Full=cDNA FLJ60143, highly similar to Homo sapiens dystrophin, transcript variant Dp140bc, mRNA {ECO:0000313|EMBL:BAG61769.1};+++[E7EQR9_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000340057};+++[E7EQS5_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000367979};+++[E7ESB2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000417123};+++[E9PDN5_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000367948};+++[F1CFE6_HUMAN|Unreviewed]SubName: Full=Truncated dystrophin protein {ECO:0000313|EMBL:ADZ31225.1}; Flags: Fragment;+++[F2WSI7_HUMAN|Unreviewed]SubName: Full=Truncated dystrophin protein {ECO:0000313|EMBL:ADZ31226.1}; Flags: Fragment;+++[F5GZY3_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000444119};+++[F8VX32_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000352894};+++[H0Y304_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000350765}; Flags: Fragment;+++[H0Y3E8_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000367977}; Flags: Fragment;+++[H0Y864_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000417725}; Flags: Fragment;+++[L8E939_HUMAN|Unreviewed]SubName: Full=Alternative protein DMD {ECO:0000313|EMBL:CCQ43246.1};+++[L8ECA9_HUMAN|Unreviewed]SubName: Full=Alternative protein DMD {ECO:0000313|EMBL:CCQ43247.1};+++[Q14172_HUMAN|Unreviewed]SubName: Full=Duchenne muscular dystrophy protein {ECO:0000313|EMBL:AAA52313.1}; SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000399897}; Flags: Fragment;+++[Q14174_HUMAN|Unreviewed]SubName: Full=Duchenne muscular dystrophy protein {ECO:0000313|EMBL:AAA52315.1}; SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000395904}; Flags: Fragment;+++[Q15945_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAB22395.2}; Flags: Fragment;+++[Q16484_HUMAN|Unreviewed]SubName: Full=DMD protein {ECO:0000313|EMBL:AAD13820.1}; Flags: Fragment;+++[Q4G0X0_HUMAN|Unreviewed]SubName: Full=DMD protein {ECO:0000313|EMBL:AAH36103.1}; SubName: Full=Dystrophin {ECO:0000313|Ensembl:ENSP00000288447};+++[Q548X2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61563.1}; Flags: Fragment;+++[Q6PK12_HUMAN|Unreviewed]SubName: Full=DMD protein {ECO:0000313|EMBL:AAH09242.1}; Flags: Fragment;+++[Q7KZ40_HUMAN|Unreviewed]SubName: Full=DMD protein {ECO:0000313|EMBL:AAA52309.1}; Flags: Fragment;+++[Q8TCV2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:CAD30261.1}; Flags: Fragment;+++[Q8WTQ2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61586.1}; Flags: Fragment;+++[Q8WYB7_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61589.1}; Flags: Fragment;+++[Q8WYB8_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61588.1}; Flags: Fragment;+++[Q8WYB9_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61585.1}; Flags: Fragment;+++[Q8WYC0_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61584.1}; Flags: Fragment;+++[Q8WYC1_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61583.1}; Flags: Fragment;+++[Q8WYC2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61582.1}; Flags: Fragment;+++[Q8WYC3_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61581.1}; Flags: Fragment;+++[Q8WYC4_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL65100.1}; Flags: Fragment;+++[Q8WYC5_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL65099.1}; Flags: Fragment;+++[Q8WYC6_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61580.1}; Flags: Fragment;+++[Q8WYC7_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61579.1}; Flags: Fragment;+++[Q8WYC8_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61578.1}; Flags: Fragment;+++[Q8WYC9_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61577.1}; Flags: Fragment;+++[Q8WYD0_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61576.1}; Flags: Fragment;+++[Q8WYD1_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61575.1}; Flags: Fragment;+++[Q8WYD2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61574.1}; Flags: Fragment;+++[Q8WYD3_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61573.1}; Flags: Fragment;+++[Q8WYD4_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61572.1}; Flags: Fragment;+++[Q8WYD5_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61571.1}; Flags: Fragment;+++[Q8WYD6_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61570.1}; Flags: Fragment;+++[Q8WYD7_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61569.1}; Flags: Fragment;+++[Q8WYD8_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61568.1}; Flags: Fragment;+++[Q8WYD9_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61567.1}; Flags: Fragment;+++[Q8WYE0_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61566.1}; Flags: Fragment;+++[Q8WYE1_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61565.1}; Flags: Fragment;+++[Q8WYE2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61564.1}; Flags: Fragment;+++[Q8WYE3_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61562.1}; Flags: Fragment;+++[Q8WYE4_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61561.1}; Flags: Fragment;+++[Q8WYE5_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61560.1}; Flags: Fragment;+++[Q8WYE6_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL65098.1}; Flags: Fragment;+++[Q8WYE7_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61559.1}; Flags: Fragment;+++[Q8WYE8_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61558.1}; Flags: Fragment;+++[Q8WYE9_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61557.1}; Flags: Fragment;+++[Q8WYF0_HUMAN|Unreviewed]SubName: Full=Duchenne muscular dystrophy gene {ECO:0000313|EMBL:CAE82077.1}; SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61556.1}; Flags: Fragment;+++[Q8WYF1_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61555.1}; Flags: Fragment;+++[Q8WYF2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61554.1}; Flags: Fragment;+++[Q8WYF3_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61553.1}; Flags: Fragment;+++[Q8WYF4_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61552.1}; Flags: Fragment;+++[Q8WYF5_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61551.1}; Flags: Fragment;+++[Q8WYF6_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAL61550.1}; Flags: Fragment;+++[Q9UEH4_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAA74506.1}; Flags: Fragment;+++[Q9UME2_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAB53001.1}; Flags: Fragment;+++[Q9UMG1_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAC51631.1}; Flags: Fragment;+++[Q9UMK6_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAA74508.1}; Flags: Fragment;+++[Q9UMK7_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAA74507.1}; Flags: Fragment;+++[Q9UMK8_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAA52330.1}; Flags: Fragment;+++[Q9UPB4_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAD03809.1}; Flags: Fragment;+++[Q9UPB5_HUMAN|Unreviewed]SubName: Full=Dystrophin {ECO:0000313|EMBL:AAD03808.1}; Flags: Fragment;"]
[1794,"'DOCK2'",133,102,101,112,"04062///Chemokine signaling pathway+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005856///cytoskeleton+++GO:0035580///specific granule lumen+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0042608///T cell receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0050690///regulation of defense response to virus by virus+++GO:0042098///T cell proliferation+++GO:0043312///neutrophil degranulation+++GO:0006935///chemotaxis+++GO:0050766///positive regulation of phagocytosis+++GO:0001768///establishment of T cell polarity+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0030036///actin cytoskeleton organization+++GO:0045060///negative thymic T cell selection+++GO:0001771///immunological synapse formation+++GO:0007264///small GTPase mediated signal transduction+++GO:0007010///cytoskeleton organization+++GO:0044351///macropinocytosis+++GO:0042110///T cell activation+++GO:0001766///membrane raft polarization+++GO:0043547///positive regulation of GTPase activity+++GO:0046631///alpha-beta T cell activation+++GO:0046633///alpha-beta T cell proliferation+++GO:0045059///positive thymic T cell selection","dedicator of cytokinesis 2","[DOCK2_HUMAN|Reviewed]RecName: Full=Dedicator of cytokinesis protein 2;+++[A0A2X0SFD3_HUMAN|Unreviewed]SubName: Full=DOCK2 {ECO:0000313|EMBL:SPT35742.1}; Flags: Fragment;+++[E5RFJ0_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 2 {ECO:0000313|Ensembl:ENSP00000428850};+++[E7ERW7_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 2 {ECO:0000313|Ensembl:ENSP00000429283};+++[F6S220_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 2 {ECO:0000313|Ensembl:ENSP00000438827};+++[H0YB76_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 2 {ECO:0000313|Ensembl:ENSP00000428841}; Flags: Fragment;+++[H7C082_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 2 {ECO:0000313|Ensembl:ENSP00000393451}; Flags: Fragment;+++[Q5XG91_HUMAN|Unreviewed]SubName: Full=DOCK2 protein {ECO:0000313|EMBL:AAH84556.1}; Flags: Fragment;"]
[1801,"'DPH1'",669.55,625.24,653.56,649.45,{"$nulls":3},"R10455///S-adenosyl-L-methionine:L-histidine-[translation elongation factor 2] 2-[(3S)-3-amino-3-carboxypropyl]transferase   S-Adenosyl-L-methionine + L-Histidine-[translation elongation factor 2] <=> 5'-Methylthioadenosine + Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine","GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0005515///protein binding","GO:0008283///cell proliferation+++GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine","diphthamide biosynthesis 1","[DPH1_HUMAN|Reviewed]RecName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000305}; EC=2.5.1.108 {ECO:0000250|UniProtKB:Q5NCQ5}; AltName: Full=Diphthamide biosynthesis protein 1; AltName: Full=Diphtheria toxin resistance protein 1 {ECO:0000305}; AltName: Full=Ovarian cancer-associated gene 1 protein; AltName: Full=S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1 {ECO:0000305};+++[A0A0A0MTR4_HUMAN|Unreviewed]SubName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000313|Ensembl:ENSP00000460431}; Flags: Fragment;+++[I3L1H5_HUMAN|Unreviewed]SubName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000313|Ensembl:ENSP00000458838}; Flags: Fragment;+++[I3L3X9_HUMAN|Unreviewed]SubName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000313|Ensembl:ENSP00000460813}; Flags: Fragment;+++[K7EQQ6_HUMAN|Unreviewed]SubName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000313|Ensembl:ENSP00000467936}; Flags: Fragment;+++[U3KQN3_HUMAN|Unreviewed]SubName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000313|Ensembl:ENSP00000476070}; Flags: Fragment;+++[V9GYC0_HUMAN|Unreviewed]SubName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000313|Ensembl:ENSP00000476598}; Flags: Fragment;+++[V9GYS2_HUMAN|Unreviewed]SubName: Full=2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 {ECO:0000313|Ensembl:ENSP00000477033}; Flags: Fragment;"]
[1820,"'ARID3A'",229,206,207,214,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0045121///membrane raft+++GO:0005737///cytoplasm","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","AT-rich interaction domain 3A","[ARI3A_HUMAN|Reviewed]RecName: Full=AT-rich interactive domain-containing protein 3A; Short=ARID domain-containing protein 3A; AltName: Full=B-cell regulator of IgH transcription; Short=Bright; AltName: Full=Dead ringer-like protein 1; AltName: Full=E2F-binding protein 1;+++[H0YFY1_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000440911}; Flags: Fragment;+++[K7EJ04_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000464969}; Flags: Fragment;"]
[1831,"'TSC22D3'",619,600,605,608,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding","GO:0034220///ion transmembrane transport+++GO:0070236///negative regulation of activation-induced cell death of T cells+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006970///response to osmotic stress","TSC22 domain family member 3","[T22D3_HUMAN|Reviewed]RecName: Full=TSC22 domain family protein 3; AltName: Full=DSIP-immunoreactive peptide; Short=Protein DIP; Short=hDIP; AltName: Full=Delta sleep-inducing peptide immunoreactor; AltName: Full=Glucocorticoid-induced leucine zipper protein; Short=GILZ; AltName: Full=TSC-22-like protein; AltName: Full=TSC-22-related protein; Short=TSC-22R;+++[D6R8Z7_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000422228}; Flags: Fragment;+++[D6R9J1_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000422060}; Flags: Fragment;+++[D6RAX8_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000424653}; Flags: Fragment;+++[D6RBL1_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000422636}; Flags: Fragment;+++[D6RCK9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000427199}; Flags: Fragment;+++[D6RD37_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000427075}; Flags: Fragment;+++[D6RD92_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000425414}; Flags: Fragment;+++[D6RDZ7_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000425158}; Flags: Fragment;+++[D6RDZ9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000425155}; Flags: Fragment;+++[E7EWD5_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000421016};+++[Q5JRJ0_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000361457};+++[Q5JRJ2_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 3 {ECO:0000313|Ensembl:ENSP00000361466};"]
[1855,"'DVL1'",1263,1394,1268,1308.33333333333,"05224///Breast cancer+++04390///Hippo signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05225///Hepatocellular carcinoma+++05166///HTLV-I infection+++04310///Wnt signaling pathway+++04916///Melanogenesis+++04150///mTOR signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04934///Cushing's syndrome+++04330///Notch signaling pathway","H00485///Robinow syndrome","M00677///Wnt signaling",null,"GO:0043005///neuron projection+++GO:0030426///growth cone+++GO:0045202///synapse+++GO:0098793///presynapse+++GO:0030136///clathrin-coated vesicle+++GO:0043197///dendritic spine+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0031410///cytoplasmic vesicle+++GO:0016328///lateral plasma membrane+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0098978///glutamatergic synapse+++GO:0014069///postsynaptic density+++GO:1990909///Wnt signalosome","GO:0019901///protein kinase binding+++GO:0005109///frizzled binding+++GO:0008013///beta-catenin binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0048365///Rac GTPase binding","GO:0021915///neural tube development+++GO:0048668///collateral sprouting+++GO:0007269///neurotransmitter secretion+++GO:0048813///dendrite morphogenesis+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0050821///protein stabilization+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0060070///canonical Wnt signaling pathway+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0022007///convergent extension involved in neural plate elongation+++GO:0006366///transcription by RNA polymerase II+++GO:0150012///positive regulation of neuron projection arborization+++GO:0060134///prepulse inhibition+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0031122///cytoplasmic microtubule organization+++GO:0099054///presynapse assembly+++GO:0007528///neuromuscular junction development+++GO:0034504///protein localization to nucleus+++GO:0032091///negative regulation of protein binding+++GO:0035556///intracellular signal transduction+++GO:0060997///dendritic spine morphogenesis+++GO:0001505///regulation of neurotransmitter levels+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0035567///non-canonical Wnt signaling pathway+++GO:1903827///regulation of cellular protein localization+++GO:0050808///synapse organization+++GO:0006469///negative regulation of protein kinase activity+++GO:1905386///positive regulation of protein localization to presynapse+++GO:0043113///receptor clustering+++GO:0090103///cochlea morphogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007411///axon guidance+++GO:0048675///axon extension+++GO:0035372///protein localization to microtubule+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:1904886///beta-catenin destruction complex disassembly+++GO:0035176///social behavior","dishevelled segment polarity protein 1","[DVL1_HUMAN|Reviewed]RecName: Full=Segment polarity protein dishevelled homolog DVL-1; Short=Dishevelled-1; AltName: Full=DSH homolog 1;"]
[1880,"'GPR183'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity+++GO:0008142///oxysterol binding","GO:0036145///dendritic cell homeostasis+++GO:0002313///mature B cell differentiation involved in immune response+++GO:0030890///positive regulation of B cell proliferation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010818///T cell chemotaxis+++GO:0002407///dendritic cell chemotaxis+++GO:0002250///adaptive immune response+++GO:0002376///immune system process+++GO:2000458///regulation of astrocyte chemotaxis+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0030595///leukocyte chemotaxis+++GO:0006959///humoral immune response+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0060326///cell chemotaxis+++GO:0061470///T follicular helper cell differentiation+++GO:0030316///osteoclast differentiation","G protein-coupled receptor 183","[GP183_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor 183 {ECO:0000305}; AltName: Full=Epstein-Barr virus-induced G-protein coupled receptor 2 {ECO:0000303|PubMed:8383238}; Short=EBI2 {ECO:0000303|PubMed:8383238}; Short=EBV-induced G-protein coupled receptor 2 {ECO:0000303|PubMed:8383238}; Short=hEBI2 {ECO:0000303|PubMed:22875855};+++[A0A024RDX2_HUMAN|Unreviewed]SubName: Full=Epstein-Barr virus induced gene 2 (Lymphocyte-specific G protein-coupled receptor), isoform CRA_a {ECO:0000313|EMBL:EAX09019.1};"]
[1912,"'PHC2'",2512,2606,2401,2506.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031519///PcG protein complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000792///heterochromatin+++GO:0035102///PRC1 complex","GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis","polyhomeotic homolog 2","[PHC2_HUMAN|Reviewed]RecName: Full=Polyhomeotic-like protein 2; Short=hPH2; AltName: Full=Early development regulatory protein 2;+++[A0A0A0MSI2_HUMAN|Unreviewed]SubName: Full=Polyhomeotic-like protein 2 {ECO:0000313|Ensembl:ENSP00000389436};+++[B3KPJ4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31867 fis, clone NT2RP7001856, highly similar to Polyhomeotic-like protein 2 {ECO:0000313|EMBL:BAG51706.1};+++[B7ZLY0_HUMAN|Unreviewed]SubName: Full=PHC2 protein {ECO:0000313|EMBL:AAI44122.1};"]
[1939,"'EIF2D'",958,870,913,913.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0022627///cytosolic small ribosomal subunit","GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0038023///signaling receptor activity","GO:0006886///intracellular protein transport+++GO:0075522///IRES-dependent viral translational initiation+++GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0032790///ribosome disassembly","eukaryotic translation initiation factor 2D","[EIF2D_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 2D; Short=eIF2d; AltName: Full=Hepatocellular carcinoma-associated antigen 56; AltName: Full=Ligatin;+++[A0A087WVB6_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000479327}; Flags: Fragment;+++[A0A087X1L6_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000484299}; Flags: Fragment;+++[A0A087X202_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000484590}; Flags: Fragment;+++[Q5SY38_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2D {ECO:0000313|Ensembl:ENSP00000394685}; Flags: Fragment;"]
[195827,"'PRXL2C'",39,43,58,46.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0016209///antioxidant activity","GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0055114///oxidation-reduction process+++GO:0098869///cellular oxidant detoxification+++GO:0045821///positive regulation of glycolytic process","peroxiredoxin like 2C","[AAED1_HUMAN|Reviewed]RecName: Full=Thioredoxin-like protein AAED1; AltName: Full=AhpC/TSA antioxidant enzyme domain-containing protein 1;+++[B7ZKK1_HUMAN|Unreviewed]SubName: Full=C9orf21 protein {ECO:0000313|EMBL:AAI36502.1};+++[H0Y5J5_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-like 2C {ECO:0000313|Ensembl:ENSP00000398933}; Flags: Fragment;+++[H0Y7F1_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-like 2C {ECO:0000313|Ensembl:ENSP00000412378}; Flags: Fragment;"]
[196403,"'DTX3'",852,1044,985,960.333333333333,"04330///Notch signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm","GO:0016874///ligase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination","deltex E3 ubiquitin ligase 3","[DTX3_HUMAN|Reviewed]RecName: Full=Probable E3 ubiquitin-protein ligase DTX3; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q61010}; AltName: Full=Protein deltex-3; Short=Deltex3; AltName: Full=RING finger protein 154; AltName: Full=RING-type E3 ubiquitin transferase DTX3 {ECO:0000305};+++[A0A024RB96_HUMAN|Unreviewed]SubName: Full=Deltex 3 homolog (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW97034.1};+++[A0A0C4DGI8_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase DTX3 {ECO:0000313|Ensembl:ENSP00000448224}; Flags: Fragment;+++[A0A1Y8EH36_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase DTX3 {ECO:0000313|Ensembl:ENSP00000449118}; Flags: Fragment;+++[F8VUZ4_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase DTX3 {ECO:0000313|Ensembl:ENSP00000449688}; Flags: Fragment;+++[F8VV96_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase DTX3 {ECO:0000313|Ensembl:ENSP00000449950}; Flags: Fragment;+++[H0YHF9_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase DTX3 {ECO:0000313|Ensembl:ENSP00000446996}; Flags: Fragment;"]
[1968,"'EIF2S3'",1326.97,1143,1201,1223.65666666667,"03013///RNA transport","H00658///Syndromic X-linked mental retardation",null,null,"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005850///eukaryotic translation initiation factor 2 complex+++GO:0005634///nucleus","GO:0008135///translation factor activity, RNA binding+++GO:0045296///cadherin binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0003924///GTPase activity","GO:0055085///transmembrane transport+++GO:0001731///formation of translation preinitiation complex+++GO:0006412///translation+++GO:0006413///translational initiation","eukaryotic translation initiation factor 2 subunit gamma","[IF2G_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 2 subunit 3; AltName: Full=Eukaryotic translation initiation factor 2 subunit gamma X; Short=eIF-2-gamma X; Short=eIF-2gX;+++[H7BZU1_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2 subunit 3 {ECO:0000313|Ensembl:ENSP00000391383}; Flags: Fragment;"]
[197370,"'NSMCE1'",662,735,655,684,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0030915///Smc5-Smc6 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000781///chromosome, telomeric region","GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006974///cellular response to DNA damage stimulus+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:0006301///postreplication repair+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0000724///double-strand break repair via homologous recombination","NSE1 homolog, SMC5-SMC6 complex component","[NSE1_HUMAN|Reviewed]RecName: Full=Non-structural maintenance of chromosomes element 1 homolog; Short=Non-SMC element 1 homolog; EC=2.3.2.27 {ECO:0000269|PubMed:20864041, ECO:0000269|PubMed:29225034};+++[H3BN81_HUMAN|Unreviewed]SubName: Full=Non-structural maintenance of chromosomes element 1 homolog {ECO:0000313|Ensembl:ENSP00000454726}; Flags: Fragment;+++[H3BR31_HUMAN|Unreviewed]SubName: Full=Non-structural maintenance of chromosomes element 1 homolog {ECO:0000313|Ensembl:ENSP00000456053};+++[H3BR73_HUMAN|Unreviewed]SubName: Full=Non-structural maintenance of chromosomes element 1 homolog {ECO:0000313|Ensembl:ENSP00000456103}; Flags: Fragment;+++[H3BSL0_HUMAN|Unreviewed]SubName: Full=Non-structural maintenance of chromosomes element 1 homolog {ECO:0000313|Ensembl:ENSP00000456754}; Flags: Fragment;+++[H3BV05_HUMAN|Unreviewed]SubName: Full=Non-structural maintenance of chromosomes element 1 homolog {ECO:0000313|Ensembl:ENSP00000457893}; Flags: Fragment;+++[I3L1I3_HUMAN|Unreviewed]SubName: Full=Non-structural maintenance of chromosomes element 1 homolog {ECO:0000313|Ensembl:ENSP00000458859}; Flags: Fragment;"]
[1993,"'ELAVL2'",259,164,233,218.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0000398///mRNA splicing, via spliceosome","ELAV like RNA binding protein 2","[ELAV2_HUMAN|Reviewed]RecName: Full=ELAV-like protein 2; AltName: Full=ELAV-like neuronal protein 1; AltName: Full=Hu-antigen B; Short=HuB; AltName: Full=Nervous system-specific RNA-binding protein Hel-N1;+++[A0A0A0MRX1_HUMAN|Unreviewed]RecName: Full=ELAV-like protein {ECO:0000256|RuleBase:RU361281};+++[B1AM48_HUMAN|Unreviewed]RecName: Full=ELAV-like protein {ECO:0000256|RuleBase:RU361281}; Flags: Fragment;+++[C9JB16_HUMAN|Unreviewed]SubName: Full=ELAV-like protein 2 {ECO:0000313|Ensembl:ENSP00000391757}; Flags: Fragment;"]
[1999,"'ELF3'",7,12,24,14.3333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0008233///peptidase activity+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0038023///signaling receptor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0001824///blastocyst development+++GO:0030855///epithelial cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0009653///anatomical structure morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007166///cell surface receptor signaling pathway+++GO:0008544///epidermis development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0006508///proteolysis+++GO:0060056///mammary gland involution","E74 like ETS transcription factor 3","[ELF3_HUMAN|Reviewed]RecName: Full=ETS-related transcription factor Elf-3; AltName: Full=E74-like factor 3; AltName: Full=Epithelial-restricted with serine box; AltName: Full=Epithelium-restricted Ets protein ESX; AltName: Full=Epithelium-specific Ets transcription factor 1; Short=ESE-1;+++[A0A024R974_HUMAN|Unreviewed]SubName: Full=E74-like factor 3 (Ets domain transcription factor, epithelial-specific ), isoform CRA_b {ECO:0000313|EMBL:EAW91391.1};+++[Q14253_HUMAN|Unreviewed]SubName: Full=Effector cell protease receptor-1 {ECO:0000313|EMBL:AAA57127.1}; Flags: Fragment;+++[Q14868_HUMAN|Unreviewed]SubName: Full=Effector cell protease receptor 1 {ECO:0000313|EMBL:AAA19687.1}; Flags: Fragment;+++[Q5SR36_HUMAN|Unreviewed]SubName: Full=ETS-related transcription factor Elf-3 {ECO:0000313|Ensembl:ENSP00000405162}; Flags: Fragment;"]
[200132,"'TCTEX1D1'",1,0,0,0.333333333333333,{"$nulls":5},"GO:0005515///protein binding",null,"Tctex1 domain containing 1","[TC1D1_HUMAN|Reviewed]RecName: Full=Tctex1 domain-containing protein 1;+++[D3DQ68_HUMAN|Unreviewed]SubName: Full=Tctex1 domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAX06520.1};+++[E9PI84_HUMAN|Unreviewed]SubName: Full=Tctex1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000436731};"]
[200558,"'APLF'",13,14,10,12.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm","GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0016829///lyase activity+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0008408///3'-5' exonuclease activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0000012///single strand break repair+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006302///double-strand break repair+++GO:0051106///positive regulation of DNA ligation+++GO:0045191///regulation of isotype switching","aprataxin and PNKP like factor","[APLF_HUMAN|Reviewed]RecName: Full=Aprataxin and PNK-like factor; EC=4.2.99.18; AltName: Full=Apurinic-apyrimidinic endonuclease APLF; AltName: Full=PNK and APTX-like FHA domain-containing protein; AltName: Full=XRCC1-interacting protein 1;+++[E9PRH6_HUMAN|Unreviewed]SubName: Full=Aprataxin and PNK-like factor {ECO:0000313|Ensembl:ENSP00000432297};+++[F8WET0_HUMAN|Unreviewed]SubName: Full=Aprataxin and PNK-like factor {ECO:0000313|Ensembl:ENSP00000393403};"]
[2009,"'EML1'",543,501,524,522.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005874///microtubule","GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0005509///calcium ion binding+++GO:0008017///microtubule binding","GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007420///brain development+++GO:0007052///mitotic spindle organization+++GO:0007405///neuroblast proliferation+++GO:0000226///microtubule cytoskeleton organization","echinoderm microtubule associated protein like 1","[EMAL1_HUMAN|Reviewed]RecName: Full=Echinoderm microtubule-associated protein-like 1; Short=EMAP-1; Short=HuEMAP-1;+++[F8W717_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000327384};+++[G3V3J1_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451269};+++[G3V3N9_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451346}; Flags: Fragment;+++[G3V497_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451669}; Flags: Fragment;+++[G3V4H6_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451805}; Flags: Fragment;+++[G3V4U5_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451991}; Flags: Fragment;+++[G3V500_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452089}; Flags: Fragment;+++[G3V538_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452160}; Flags: Fragment;+++[G3V5C8_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452292}; Flags: Fragment;+++[H0YJD8_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451288}; Flags: Fragment;+++[H0YJK4_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451706}; Flags: Fragment;+++[H0YJS9_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452063}; Flags: Fragment;+++[H0YJY3_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452474}; Flags: Fragment;"]
[201255,"'LRRC45'",212,210,209,210.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding",null,"leucine rich repeat containing 45","[LRC45_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 45;+++[J3KTD4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 45 {ECO:0000313|Ensembl:ENSP00000462928}; Flags: Fragment;"]
[201514,"'ZNF584'",157,145,183.99,161.996666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 584","[ZN584_HUMAN|Reviewed]RecName: Full=Zinc finger protein 584;+++[B4DQS1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57563, moderately similar to Zinc finger protein 584 {ECO:0000313|EMBL:BAG61033.1};+++[F6W0P0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000320731};+++[M0QZA3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000470404};+++[M0R0A3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000471105};+++[M0R2W6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000472853};+++[M0R3F5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000473184}; Flags: Fragment;+++[Q8WVQ2_HUMAN|Unreviewed]SubName: Full=ZNF584 protein {ECO:0000313|EMBL:AAH17651.1}; Flags: Fragment;"]
[201626,"'PDE12'",351,280.09,327.01,319.366666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0016787///hydrolase activity+++GO:0004527///exonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0034611///oligoribonucleotidase activity+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0046872///metal ion binding+++GO:0004518///nuclease activity","GO:0071346///cellular response to interferon-gamma+++GO:0035457///cellular response to interferon-alpha+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0045070///positive regulation of viral genome replication+++GO:0000958///mitochondrial mRNA catabolic process+++GO:0060548///negative regulation of cell death+++GO:0071359///cellular response to dsRNA+++GO:0051607///defense response to virus+++GO:0006397///mRNA processing+++GO:0044528///regulation of mitochondrial mRNA stability+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0090324///negative regulation of oxidative phosphorylation","phosphodiesterase 12","[PDE12_HUMAN|Reviewed]RecName: Full=2',5'-phosphodiesterase 12; Short=2'-PDE; Short=2-PDE; EC=3.1.4.-; AltName: Full=Mitochondrial deadenylase; EC=3.1.13.4; Flags: Precursor;+++[F6T1Q0_HUMAN|Unreviewed]SubName: Full=2',5'-phosphodiesterase 12 {ECO:0000313|Ensembl:ENSP00000420626};"]
[202500,"'TCTE1'",5,2,7,4.66666666666667,{"$nulls":4},"GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0005856///cytoskeleton+++GO:0031514///motile cilium+++GO:0005737///cytoplasm",null,"GO:0030317///flagellated sperm motility","t-complex-associated-testis-expressed 1","[DRC5_HUMAN|Reviewed]RecName: Full=Dynein regulatory complex subunit 5 {ECO:0000250|UniProtKB:A6H639}; AltName: Full=T-complex-associated testis-expressed protein 1; Short=Tcte-1;+++[Q5JU01_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex subunit 5 {ECO:0000313|Ensembl:ENSP00000360559};"]
[203,"'AK1'",842.11,969.01,854.1,888.406666666667,"01130///Biosynthesis of antibiotics+++00730///Thiamine metabolism+++00230///Purine metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00092///T-B-Severe combined immunodeficiencies (SCIDs)+++H01128///Reticular dysgenesis+++H00674///Anemia due to disorders of nucleotide metabolism","M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R01547///ATP:dAMP phosphotransferase   ATP + dAMP <=> ADP + dADP+++R00127///ATP:AMP phosphotransferase   ATP + AMP <=> 2 ADP+++R11319///ADP:thiamin-diphosphate phosphotransferase   Thiamin diphosphate + ADP <=> Thiamin triphosphate + AMP","GO:0005829///cytosol+++GO:0036126///sperm flagellum+++GO:0005886///plasma membrane+++GO:0001520///outer dense fiber+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0016740///transferase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0004017///adenylate kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0019205///nucleobase-containing compound kinase activity","GO:0046940///nucleoside monophosphate phosphorylation+++GO:0046033///AMP metabolic process+++GO:0016310///phosphorylation+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0046034///ATP metabolic process+++GO:0006172///ADP biosynthetic process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0007050///cell cycle arrest+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0006165///nucleoside diphosphate phosphorylation","adenylate kinase 1","[KAD1_HUMAN|Reviewed]RecName: Full=Adenylate kinase isoenzyme 1 {ECO:0000255|HAMAP-Rule:MF_03171}; Short=AK 1 {ECO:0000255|HAMAP-Rule:MF_03171}; EC=2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03171}; EC=2.7.4.6 {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=ATP-AMP transphosphorylase 1 {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03171}; AltName: Full=Myokinase {ECO:0000255|HAMAP-Rule:MF_03171};+++[F8VRY5_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 1 {ECO:0000313|Ensembl:ENSP00000448741};+++[H0YID2_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 1 {ECO:0000313|Ensembl:ENSP00000449130}; Flags: Fragment;+++[Q5T9B7_HUMAN|Unreviewed]RecName: Full=Adenylate kinase isoenzyme 1 {ECO:0000256|HAMAP-Rule:MF_03171}; Short=AK 1 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.3 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.6 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP-AMP transphosphorylase 1 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Adenylate monophosphate kinase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Myokinase {ECO:0000256|HAMAP-Rule:MF_03171};+++[Q6FGX9_HUMAN|Unreviewed]RecName: Full=Adenylate kinase isoenzyme 1 {ECO:0000256|HAMAP-Rule:MF_03171}; Short=AK 1 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.3 {ECO:0000256|HAMAP-Rule:MF_03171}; EC=2.7.4.6 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP-AMP transphosphorylase 1 {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=ATP:AMP phosphotransferase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Adenylate monophosphate kinase {ECO:0000256|HAMAP-Rule:MF_03171}; AltName: Full=Myokinase {ECO:0000256|HAMAP-Rule:MF_03171};"]
[203547,"'VMA21'",286.57,245.02,263,264.863333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005764///lysosome+++GO:0031410///cytoplasmic vesicle+++GO:0005789///endoplasmic reticulum membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005783///endoplasmic reticulum",null,"GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0043462///regulation of ATPase activity","VMA21, vacuolar ATPase assembly factor","[VMA21_HUMAN|Reviewed]RecName: Full=Vacuolar ATPase assembly integral membrane protein VMA21 {ECO:0000255|HAMAP-Rule:MF_03058}; AltName: Full=Myopathy with excessive autophagy protein;"]
[2047,"'EPHB1'",105,84,144,111,"04360///Axon guidance","H00992///Seckel syndrome",null,null,"GO:0098978///glutamatergic synapse+++GO:0043005///neuron projection+++GO:0005576///extracellular region+++GO:0030425///dendrite+++GO:0032433///filopodium tip+++GO:0045121///membrane raft+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0031901///early endosome membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0005003///ephrin receptor activity+++GO:0016740///transferase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005524///ATP binding+++GO:0008046///axon guidance receptor activity+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0044877///protein-containing complex binding+++GO:0004672///protein kinase activity","GO:0022008///neurogenesis+++GO:0030154///cell differentiation+++GO:0031589///cell-substrate adhesion+++GO:1901214///regulation of neuron death+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1902725///negative regulation of satellite cell differentiation+++GO:0060996///dendritic spine development+++GO:0051965///positive regulation of synapse assembly+++GO:0021545///cranial nerve development+++GO:0016310///phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0060326///cell chemotaxis+++GO:1902723///negative regulation of skeletal muscle satellite cell proliferation+++GO:0046777///protein autophosphorylation+++GO:0007155///cell adhesion+++GO:0048013///ephrin receptor signaling pathway+++GO:0021631///optic nerve morphogenesis+++GO:0060997///dendritic spine morphogenesis+++GO:0048593///camera-type eye morphogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0007399///nervous system development+++GO:0001525///angiogenesis+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0007411///axon guidance+++GO:0046328///regulation of JNK cascade+++GO:0061351///neural precursor cell proliferation+++GO:0006468///protein phosphorylation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0001771///immunological synapse formation+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0014719///skeletal muscle satellite cell activation+++GO:0043066///negative regulation of apoptotic process+++GO:0009968///negative regulation of signal transduction+++GO:0031290///retinal ganglion cell axon guidance","EPH receptor B1","[EPHB1_HUMAN|Reviewed]RecName: Full=Ephrin type-B receptor 1; EC=2.7.10.1; AltName: Full=ELK; AltName: Full=EPH tyrosine kinase 2; AltName: Full=EPH-like kinase 6; Short=EK6; Short=hEK6; AltName: Full=Neuronally-expressed EPH-related tyrosine kinase; Short=NET; AltName: Full=Tyrosine-protein kinase receptor EPH-2; Flags: Precursor;+++[C9J466_HUMAN|Unreviewed]SubName: Full=Ephrin type-B receptor 1 {ECO:0000313|Ensembl:ENSP00000417216}; Flags: Fragment;+++[C9J6S4_HUMAN|Unreviewed]SubName: Full=Ephrin type-B receptor 1 {ECO:0000313|Ensembl:ENSP00000418352}; Flags: Fragment;+++[C9JB88_HUMAN|Unreviewed]SubName: Full=Ephrin type-B receptor 1 {ECO:0000313|Ensembl:ENSP00000417435}; Flags: Fragment;+++[C9K090_HUMAN|Unreviewed]SubName: Full=Ephrin type-B receptor 1 {ECO:0000313|Ensembl:ENSP00000419688}; Flags: Fragment;+++[F8WDG5_HUMAN|Unreviewed]SubName: Full=Ephrin type-B receptor 1 {ECO:0000313|Ensembl:ENSP00000420338};"]
[205251,"'MTLN'",108,118,90,105.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031305///integral component of mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane",null,"GO:0031334///positive regulation of protein complex assembly+++GO:0051284///positive regulation of sequestering of calcium ion+++GO:0010918///positive regulation of mitochondrial membrane potential","mitoregulin","[MTLN_HUMAN|Reviewed]RecName: Full=Mitoregulin {ECO:0000303|PubMed:29949756, ECO:0000312|HGNC:HGNC:27339}; AltName: Full=Small integral membrane protein 37 {ECO:0000312|HGNC:HGNC:27339};"]
[2069,"'EREG'",1,0,0,0.333333333333333,"05210///Colorectal cancer+++04012///ErbB signaling pathway+++04151///PI3K-Akt signaling pathway+++04010///MAPK signaling pathway","H00020///Colorectal cancer",null,null,"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005887///integral component of plasma membrane","GO:0005515///protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0008083///growth factor activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity","GO:0008285///negative regulation of cell proliferation+++GO:0000165///MAPK cascade+++GO:0001550///ovarian cumulus expansion+++GO:0008284///positive regulation of cell proliferation+++GO:0038128///ERBB2 signaling pathway+++GO:0045410///positive regulation of interleukin-6 biosynthetic process+++GO:0043434///response to peptide hormone+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0030154///cell differentiation+++GO:0051781///positive regulation of cell division+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001556///oocyte maturation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0042108///positive regulation of cytokine biosynthetic process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0009299///mRNA transcription+++GO:0009887///animal organ morphogenesis+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0001525///angiogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030728///ovulation+++GO:0007143///female meiotic nuclear division+++GO:0045860///positive regulation of protein kinase activity+++GO:0043616///keratinocyte proliferation+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:0030216///keratinocyte differentiation+++GO:0009653///anatomical structure morphogenesis+++GO:0045740///positive regulation of DNA replication+++GO:0042060///wound healing+++GO:0045089///positive regulation of innate immune response+++GO:0007275///multicellular organism development+++GO:0007267///cell-cell signaling+++GO:0048160///primary follicle stage+++GO:0042700///luteinizing hormone signaling pathway+++GO:2000145///regulation of cell motility+++GO:0042327///positive regulation of phosphorylation+++GO:0001819///positive regulation of cytokine production+++GO:0051151///negative regulation of smooth muscle cell differentiation+++GO:0007173///epidermal growth factor receptor signaling pathway","epiregulin","[EREG_HUMAN|Reviewed]RecName: Full=Proepiregulin; Contains: RecName: Full=Epiregulin; Short=EPR; Flags: Precursor;+++[L8E9W3_HUMAN|Unreviewed]SubName: Full=Alternative protein EREG {ECO:0000313|EMBL:CCQ43138.1};"]
[2079,"'ERH'",472,514,432,472.666666666667,{"$nulls":4},"GO:0030496///midbody+++GO:0034709///methylosome","GO:0008327///methyl-CpG binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0006221///pyrimidine nucleotide biosynthetic process+++GO:0006213///pyrimidine nucleoside metabolic process+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0006139///nucleobase-containing compound metabolic process","ERH, mRNA splicing and mitosis factor","[ERH_HUMAN|Reviewed]RecName: Full=Enhancer of rudimentary homolog;+++[A0A024R6D4_HUMAN|Unreviewed]RecName: Full=Enhancer of rudimentary homolog {ECO:0000256|PIRNR:PIRNR016393};+++[G3V279_HUMAN|Unreviewed]SubName: Full=Enhancer of rudimentary homolog {ECO:0000313|Ensembl:ENSP00000450503};"]
[2117,"'ETV3'",248,175,204,209,{"$nulls":4},"GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0090571///RNA polymerase II transcription repressor complex","GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003674///molecular_function+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0008150///biological_process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008285///negative regulation of cell proliferation+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus","ETS variant 3","[ETV3_HUMAN|Reviewed]RecName: Full=ETS translocation variant 3; AltName: Full=ETS domain transcriptional repressor PE1; Short=PE-1; AltName: Full=Mitogenic Ets transcriptional suppressor;"]
[2132,"'EXT2'",2653,2365,2376,2464.66666666667,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin+++01100///Metabolic pathways","H00493///Heparan sulfate proteoglycan gene defects+++H00122///Multiple exostoses","M00059///Glycosaminoglycan biosynthesis, heparan sulfate backbone","R05935///UDP-D-glucuronate + G00162 <=> UDP + G00163+++R10139///G00165 + UDP-N-acetyl-D-glucosamine <=> G13062 + UDP+++R10138///G00164 + UDP-D-glucuronate <=> G00165 + UDP","GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0043541///UDP-N-acetylglucosamine transferase complex+++GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane","GO:0008375///acetylglucosaminyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0050509///N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0042328///heparan sulfate N-acetylglucosaminyltransferase activity+++GO:0015020///glucuronosyltransferase activity+++GO:0050508///glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity","GO:0006024///glycosaminoglycan biosynthetic process+++GO:0033692///cellular polysaccharide biosynthetic process+++GO:0006486///protein glycosylation+++GO:0015014///heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process+++GO:0001503///ossification+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0001707///mesoderm formation","exostosin glycosyltransferase 2","[EXT2_HUMAN|Reviewed]RecName: Full=Exostosin-2; EC=2.4.1.224; EC=2.4.1.225; AltName: Full=Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; AltName: Full=Multiple exostoses protein 2; AltName: Full=Putative tumor suppressor protein EXT2;+++[D3DR24_HUMAN|Unreviewed]SubName: Full=Exostoses (Multiple) 2, isoform CRA_a {ECO:0000313|EMBL:EAW68069.1};"]
[214,"'ALCAM'",4744,3608,3294,3882,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0009897///external side of plasma membrane+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0042101///T cell receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0030425///dendrite+++GO:0031226///intrinsic component of plasma membrane+++GO:0001772///immunological synapse+++GO:0005925///focal adhesion","GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0002250///adaptive immune response+++GO:0008045///motor neuron axon guidance+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0031290///retinal ganglion cell axon guidance+++GO:0007411///axon guidance+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0048846///axon extension involved in axon guidance+++GO:1990138///neuron projection extension","activated leukocyte cell adhesion molecule","[CD166_HUMAN|Reviewed]RecName: Full=CD166 antigen; AltName: Full=Activated leukocyte cell adhesion molecule; AltName: CD_antigen=CD166; Flags: Precursor;+++[B3KNN9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30070 fis, clone ASTRO2000046, highly similar to CD166 ANTIGEN {ECO:0000313|EMBL:BAG51401.1};+++[F5GXJ9_HUMAN|Unreviewed]SubName: Full=CD166 antigen {ECO:0000313|Ensembl:ENSP00000418213};+++[H7C543_HUMAN|Unreviewed]SubName: Full=CD166 antigen {ECO:0000313|Ensembl:ENSP00000418937}; Flags: Fragment;"]
[2177,"'FANCD2'",27,24,30,27,"03460///Fanconi anemia pathway","H00238///Fanconi anemia",null,null,"GO:0005730///nucleolus+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0000793///condensed chromosome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0070182///DNA polymerase binding+++GO:0005515///protein binding","GO:0048854///brain morphogenesis+++GO:0007276///gamete generation+++GO:2000348///regulation of CD40 signaling pathway+++GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0050727///regulation of inflammatory response+++GO:0007129///synapsis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0097150///neuronal stem cell population maintenance+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0010332///response to gamma radiation+++GO:0034599///cellular response to oxidative stress+++GO:0007049///cell cycle","FA complementation group D2","[FACD2_HUMAN|Reviewed]RecName: Full=Fanconi anemia group D2 protein; Short=Protein FACD2;+++[A0A024R2G2_HUMAN|Unreviewed]SubName: Full=Fanconi anemia, complementation group D2, isoform CRA_b {ECO:0000313|EMBL:EAW64058.1};+++[F8WE37_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group D2 protein {ECO:0000313|Ensembl:ENSP00000402166};+++[H7BZJ7_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group D2 protein {ECO:0000313|Ensembl:ENSP00000389936}; Flags: Fragment;"]
[2181,"'ACSL3'",969,802,812,861,"01212///Fatty acid metabolism+++04714///Thermogenesis+++01100///Metabolic pathways+++02024///Quorum sensing+++00061///Fatty acid biosynthesis+++00071///Fatty acid degradation+++04920///Adipocytokine signaling pathway+++04146///Peroxisome+++03320///PPAR signaling pathway+++04216///Ferroptosis","H00480///Non-syndromic X-linked mental retardation","M00086///beta-Oxidation, acyl-CoA synthesis","R01280///Palmitate:CoA ligase (AMP-forming)   ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate","GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0005739///mitochondrion+++GO:0031090///organelle membrane+++GO:0005777///peroxisome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005811///lipid droplet+++GO:0016020///membrane","GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0019904///protein domain specific binding+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding+++GO:0016874///ligase activity+++GO:0102391///decanoate-CoA ligase activity","GO:2001247///positive regulation of phosphatidylcholine biosynthetic process+++GO:0014070///response to organic cyclic compound+++GO:0051047///positive regulation of secretion+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:0007584///response to nutrient+++GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0007420///brain development+++GO:0006631///fatty acid metabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0044539///long-chain fatty acid import","acyl-CoA synthetase long chain family member 3","[ACSL3_HUMAN|Reviewed]RecName: Full=Long-chain-fatty-acid--CoA ligase 3; EC=6.2.1.3; AltName: Full=Long-chain acyl-CoA synthetase 3; Short=LACS 3;+++[A0A024R497_HUMAN|Unreviewed]SubName: Full=Acyl-CoA synthetase long-chain family member 3, isoform CRA_a {ECO:0000313|EMBL:EAW70809.1};+++[C9JC11_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase 3 {ECO:0000313|Ensembl:ENSP00000416913}; Flags: Fragment;+++[F5GWH2_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase 3 {ECO:0000313|Ensembl:ENSP00000441643}; Flags: Fragment;+++[F5H062_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase 3 {ECO:0000313|Ensembl:ENSP00000438342}; Flags: Fragment;+++[H7BYZ7_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase 3 {ECO:0000313|Ensembl:ENSP00000385157}; Flags: Fragment;+++[Q6PIM8_HUMAN|Unreviewed]SubName: Full=ACSL3 protein {ECO:0000313|EMBL:AAH32144.1}; Flags: Fragment;"]
[2197,"'FAU'",1398,1507,1234,1379.66666666667,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes+++M00179///Ribosome, archaea",null,"GO:0005575///cellular_component+++GO:0015935///small ribosomal subunit+++GO:0005840///ribosome+++GO:0005829///cytosol+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0002227///innate immune response in mucosa+++GO:0006412///translation+++GO:0008150///biological_process+++GO:0006413///translational initiation","FAU, ubiquitin like and ribosomal protein S30 fusion","[RS30_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S30; AltName: Full=Small ribosomal subunit protein eS30 {ECO:0000303|PubMed:24524803};+++[UBIM_HUMAN|Reviewed]RecName: Full=Ubiquitin-like protein FUBI;+++[E9PM49_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein S30 {ECO:0000256|RuleBase:RU364011}; Flags: Fragment;+++[E9PMS9_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S30 {ECO:0000313|Ensembl:ENSP00000413848};+++[E9PR30_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein S30 {ECO:0000256|RuleBase:RU364011};+++[J3KN89_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S30 {ECO:0000313|Ensembl:ENSP00000279259};"]
[219743,"'TYSND1'",207,193,243,214.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0004252///serine-type endopeptidase activity+++GO:0002020///protease binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0008236///serine-type peptidase activity+++GO:0008233///peptidase activity","GO:0031998///regulation of fatty acid beta-oxidation+++GO:0006508///proteolysis+++GO:0006625///protein targeting to peroxisome+++GO:0016485///protein processing+++GO:0051260///protein homooligomerization","trypsin domain containing 1","[TYSD1_HUMAN|Reviewed]RecName: Full=Peroxisomal leader peptide-processing protease; EC=3.4.21.-; AltName: Full=Trypsin domain-containing protein 1; Contains: RecName: Full=Peroxisomal leader peptide-processing protease, 15 kDa form; Contains: RecName: Full=Peroxisomal leader peptide-processing protease, 45 kDa form;"]
[219960,"'OR10Q1'",0,1,3,1.33333333333333,"04740///Olfactory transduction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity+++GO:0005549///odorant binding+++GO:0004984///olfactory receptor activity","GO:0050896///response to stimulus+++GO:0007608///sensory perception of smell+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","olfactory receptor family 10 subfamily Q member 1","[O10Q1_HUMAN|Reviewed]RecName: Full=Olfactory receptor 10Q1; AltName: Full=Olfactory receptor OR11-233;+++[A0A126GVI6_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};"]
[220164,"'DOK6'",152,95,124,123.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04514///Cell adhesion molecules (CAMs)","H00408///Type I diabetes mellitus",null,null,"GO:0005829///cytosol","GO:0005515///protein binding","GO:0007411///axon guidance","docking protein 6","[DOK6_HUMAN|Reviewed]RecName: Full=Docking protein 6; AltName: Full=Downstream of tyrosine kinase 6;+++[J3KTH4_HUMAN|Unreviewed]SubName: Full=Docking protein 6 {ECO:0000313|Ensembl:ENSP00000462984}; Flags: Fragment;"]
[220869,"'CBWD5'",175.32,171.48,146.28,164.36,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus","GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","COBW domain containing 5","[CBWD3_HUMAN|Reviewed]RecName: Full=COBW domain-containing protein 3; AltName: Full=Cobalamin synthase W domain-containing protein 3;+++[CBWD5_HUMAN|Reviewed]RecName: Full=COBW domain-containing protein 5; AltName: Full=Cobalamin synthase W domain-containing protein 5;+++[A0A0A6YYH9_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000405076};+++[E7EUZ7_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000420326};+++[H0Y857_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000417466}; Flags: Fragment;+++[O60748_HUMAN|Unreviewed]SubName: Full=COBW-like placental protein {ECO:0000313|EMBL:AAC17121.1}; Flags: Fragment;+++[Q5JTY1_HUMAN|Unreviewed]SubName: Full=CBWD5 protein {ECO:0000313|EMBL:AAH43420.1};+++[Q5RIB0_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000397999};+++[Q5RIB3_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000366609};+++[Q5RIB5_HUMAN|Unreviewed]SubName: Full=COBW domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000475010}; SubName: Full=COBW domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000366601};+++[Q6NVZ8_HUMAN|Unreviewed]SubName: Full=CBWD5 protein {ECO:0000313|EMBL:AAH67803.1}; SubName: Full=COBW domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000419839};+++[Q9H2J8_HUMAN|Unreviewed]SubName: Full=DC36 {ECO:0000313|EMBL:AAG44700.1};"]
[221079,"'ARL5B'",248,155,202,201.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005802///trans-Golgi network+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0016192///vesicle-mediated transport+++GO:1903292///protein localization to Golgi membrane+++GO:0006886///intracellular protein transport","ADP ribosylation factor like GTPase 5B","[ARL5B_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 5B; AltName: Full=ADP-ribosylation factor-like protein 8;+++[B0YIW9_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 5B {ECO:0000313|EMBL:EAW86190.1}; SubName: Full=ADP-ribosylation factor-like protein 5B {ECO:0000313|EMBL:ACA05947.1};"]
[221322,"'TBC1D32'",35,23,30,29.3333333333333,{"$nulls":4},"GO:0042995///cell projection+++GO:0005929///cilium+++GO:0005737///cytoplasm","GO:0004519///endonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0043010///camera-type eye development+++GO:0007275///multicellular organism development+++GO:0021915///neural tube development+++GO:0042733///embryonic digit morphogenesis+++GO:0007224///smoothened signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0060041///retina development in camera-type eye+++GO:0003406///retinal pigment epithelium development+++GO:0002088///lens development in camera-type eye+++GO:1905515///non-motile cilium assembly+++GO:0061512///protein localization to cilium+++GO:0007507///heart development","TBC1 domain family member 32","[BROMI_HUMAN|Reviewed]RecName: Full=Protein broad-minded; AltName: Full=TBC1 domain family member 32;+++[A2A304_HUMAN|Unreviewed]SubName: Full=Protein broad-minded {ECO:0000313|Ensembl:ENSP00000397993}; Flags: Fragment;+++[H0YBP0_HUMAN|Unreviewed]SubName: Full=Protein broad-minded {ECO:0000313|Ensembl:ENSP00000429928}; Flags: Fragment;"]
[221481,"'ARMC12'",16,11,12,13,{"$nulls":4},"GO:0005634///nucleus",null,null,"armadillo repeat containing 12","[ARM12_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing protein 12;+++[F8WC51_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 12 {ECO:0000313|Ensembl:ENSP00000418825};"]
[221830,"'TWISTNB'",206,137,148,163.666666666667,"00230///Purine metabolism+++00240///Pyrimidine metabolism+++03020///RNA polymerase+++01100///Metabolic pathways",null,"M00182///RNA polymerase I, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA","GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005736///RNA polymerase I complex+++GO:0005634///nucleus","GO:0001054///RNA polymerase I activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006363///termination of RNA polymerase I transcription+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0006351///transcription, DNA-templated","TWIST neighbor","[RPA43_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase I subunit RPA43; AltName: Full=Twist neighbor protein;+++[L8E9H7_HUMAN|Unreviewed]SubName: Full=Alternative protein TWISTNB {ECO:0000313|EMBL:CCQ43008.1};"]
[222166,"'MTURN'",719,548,661,642.666666666667,{"$nulls":6},"GO:0007275///multicellular organism development","maturin, neural progenitor differentiation regulator homolog","[MTURN_HUMAN|Reviewed]RecName: Full=Maturin; AltName: Full=Maturin neural progenitor differentiation regulator protein homolog; AltName: Full=Protein Ells1;+++[A0A090N8P1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAL24456.1};+++[C9JBT1_HUMAN|Unreviewed]SubName: Full=Maturin {ECO:0000313|Ensembl:ENSP00000415658}; Flags: Fragment;"]
[222611,"'ADGRF2'",2,1,6,3,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","adhesion G protein-coupled receptor F2","[AGRF2_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor F2; AltName: Full=G-protein coupled receptor 111; AltName: Full=G-protein coupled receptor PGR20;+++[D6R9E2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor F2 {ECO:0000313|Ensembl:ENSP00000422934};"]
[223082,"'ZNRF2'",124,106,99,109.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005764///lysosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0045202///synapse","GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination","zinc and ring finger 2","[ZNRF2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase ZNRF2; EC=2.3.2.27; AltName: Full=Protein Ells2; AltName: Full=RING finger protein 202; AltName: Full=RING-type E3 ubiquitin transferase ZNRF2; AltName: Full=Zinc/RING finger protein 2;+++[A0A090N8Y8_HUMAN|Unreviewed]SubName: Full=Zinc and ring finger 2, isoform CRA_b {ECO:0000313|EMBL:EAW93939.1}; SubName: Full=Zinc finger/RING finger 2 {ECO:0000313|EMBL:EAL24455.1};"]
[2254,"'FGF9'",6,6,1,4.33333333333333,"04015///Rap1 signaling pathway+++05200///Pathways in cancer+++04810///Regulation of actin cytoskeleton+++04014///Ras signaling pathway+++05218///Melanoma+++04151///PI3K-Akt signaling pathway+++04010///MAPK signaling pathway+++05226///Gastric cancer+++05224///Breast cancer","H00642///Lacrimo-auriculo-dento-digital syndrome (LADD)+++H01728///Potter syndrome+++H01854///Metacarpal 4-5 fusion (MF4)+++H00255///Hypogonadotropic hypogonadism+++H01905///Trichomegaly+++H00605///Deafness, autosomal recessive+++H00041///Kaposi's sarcoma+++H00484///Other brachydactylies+++H00677///Aplasia of lacrimal and salivary glands",null,null,"GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005104///fibroblast growth factor receptor binding+++GO:0008201///heparin binding+++GO:0004713///protein tyrosine kinase activity+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0008083///growth factor activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity","GO:0021762///substantia nigra development+++GO:0002062///chondrocyte differentiation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0001654///eye development+++GO:0007275///multicellular organism development+++GO:0048706///embryonic skeletal system development+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:1905931///negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching+++GO:0043410///positive regulation of MAPK cascade+++GO:0060484///lung-associated mesenchyme development+++GO:0046854///phosphatidylinositol phosphorylation+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0001649///osteoblast differentiation+++GO:0042472///inner ear morphogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0008584///male gonad development+++GO:0030238///male sex determination+++GO:0006606///protein import into nucleus+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0048566///embryonic digestive tract development+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0051781///positive regulation of cell division+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030324///lung development+++GO:0007165///signal transduction+++GO:0010628///positive regulation of gene expression+++GO:0030154///cell differentiation+++GO:0010469///regulation of signaling receptor activity+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0030326///embryonic limb morphogenesis+++GO:0032927///positive regulation of activin receptor signaling pathway+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0000165///MAPK cascade+++GO:0008284///positive regulation of cell proliferation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0007267///cell-cell signaling+++GO:0048505///regulation of timing of cell differentiation+++GO:0001525///angiogenesis","fibroblast growth factor 9","[FGF9_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor 9; Short=FGF-9; AltName: Full=Glia-activating factor; Short=GAF; AltName: Full=Heparin-binding growth factor 9; Short=HBGF-9; Flags: Precursor;"]
[22795,"'NID2'",4692,3929,5445,4688.66666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix","GO:0005518///collagen binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0005509///calcium ion binding","GO:0071711///basement membrane organization+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0030198///extracellular matrix organization","nidogen 2","[NID2_HUMAN|Reviewed]RecName: Full=Nidogen-2; Short=NID-2; AltName: Full=Osteonidogen; Flags: Precursor;+++[A0A087WZP6_HUMAN|Unreviewed]SubName: Full=Nidogen-2 {ECO:0000313|Ensembl:ENSP00000482803};+++[H0YJV3_HUMAN|Unreviewed]SubName: Full=Nidogen-2 {ECO:0000313|Ensembl:ENSP00000452190}; Flags: Fragment;+++[L8EAL3_HUMAN|Unreviewed]SubName: Full=Alternative protein NID2 {ECO:0000313|EMBL:CCQ43398.1};+++[Q8IV28_HUMAN|Unreviewed]SubName: Full=NID2 protein {ECO:0000313|EMBL:AAH35608.1};"]
[22808,"'MRAS'",1321,1216,1181,1239.33333333333,"04140///Autophagy - animal+++04010///MAPK signaling pathway+++05205///Proteoglycans in cancer+++04014///Ras signaling pathway+++05166///HTLV-I infection+++04137///Mitophagy - animal+++04218///Cellular senescence+++04810///Regulation of actin cytoskeleton+++04015///Rap1 signaling pathway+++04371///Apelin signaling pathway+++04625///C-type lectin receptor signaling pathway+++04072///Phospholipase D signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0030742///GTP-dependent protein binding+++GO:0005515///protein binding","GO:1990830///cellular response to leukemia inhibitory factor+++GO:0030036///actin cytoskeleton organization+++GO:0007517///muscle organ development+++GO:0007265///Ras protein signal transduction+++GO:0007275///multicellular organism development+++GO:0007165///signal transduction","muscle RAS oncogene homolog","[RASM_HUMAN|Reviewed]RecName: Full=Ras-related protein M-Ras; AltName: Full=Ras-related protein R-Ras3; Flags: Precursor;+++[C9J601_HUMAN|Unreviewed]SubName: Full=Ras-related protein M-Ras {ECO:0000313|Ensembl:ENSP00000417092}; Flags: Fragment;+++[C9J8Q6_HUMAN|Unreviewed]SubName: Full=Ras-related protein M-Ras {ECO:0000313|Ensembl:ENSP00000417685}; Flags: Fragment;+++[Q6FGP0_HUMAN|Unreviewed]SubName: Full=MRAS protein {ECO:0000313|EMBL:CAG46864.1}; SubName: Full=Muscle RAS oncogene homolog, isoform CRA_a {ECO:0000313|EMBL:EAW79068.1}; SubName: Full=cDNA FLJ42964 fis, clone BRSTN2013741, highly similar to Ras-related protein M-Ras {ECO:0000313|EMBL:BAG54117.1}; Flags: Fragment;+++[Q8WVM9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAH17733.1}; Flags: Fragment;"]
[22844,"'FRMPD1'",33,25,39,32.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0005515///protein binding","GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0090150///establishment of protein localization to membrane","FERM and PDZ domain containing 1","[FRPD1_HUMAN|Reviewed]RecName: Full=FERM and PDZ domain-containing protein 1; AltName: Full=FERM domain-containing protein 2;+++[F5H0G3_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000439868}; Flags: Fragment;"]
[22856,"'CHSY1'",531,376,476,461,"01100///Metabolic pathways+++00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate","H01497///Temtamy preaxial brachydactyly syndrome (TPBS)","M00058///Glycosaminoglycan biosynthesis, chondroitin sulfate backbone","R05932///UDP-N-acetyl-D-galactosamine + G00159 <=> UDP + G00160+++R07336///alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase   UDP-glucuronate + N-Acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan+++R05934///UDP-N-acetyl-D-galactosamine + G00180 <=> UDP + G00161+++R04603///UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase   UDP-N-acetyl-D-galactosamine + D-Glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan <=> UDP + N-Acetyl-beta-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan+++R05931///UDP-D-glucuronate + G00158 <=> UDP + G00159+++R05933///UDP-D-glucuronate + G00160 <=> UDP + G00180","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0000139///Golgi membrane+++GO:0032580///Golgi cisterna membrane+++GO:0005794///Golgi apparatus","GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0050510///N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding","GO:0051216///cartilage development+++GO:0009954///proximal/distal pattern formation+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0030279///negative regulation of ossification+++GO:0051923///sulfation+++GO:0060349///bone morphogenesis+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0031667///response to nutrient levels+++GO:0002063///chondrocyte development","chondroitin sulfate synthase 1","[CHSS1_HUMAN|Reviewed]RecName: Full=Chondroitin sulfate synthase 1; EC=2.4.1.175; EC=2.4.1.226; AltName: Full=Chondroitin glucuronyltransferase 1; AltName: Full=Chondroitin synthase 1; Short=ChSy-1; AltName: Full=Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; AltName: Full=N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; AltName: Full=N-acetylgalactosaminyltransferase 1;+++[A0A2R8Y7B7_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU364016}; EC=2.4.1.- {ECO:0000256|RuleBase:RU364016}; Flags: Fragment;+++[L8E844_HUMAN|Unreviewed]SubName: Full=Alternative protein CHSY1 {ECO:0000313|EMBL:CCQ43470.1};"]
[22880,"'MORC2'",1054,1043,991,1029.33333333333,"04140///Autophagy - animal+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04120///Ubiquitin mediated proteolysis+++04668///TNF signaling pathway+++04137///Mitophagy - animal+++04144///Endocytosis","H01901///Barrett's esophagus+++H01232///Syndromic multisystem autoimmune disease",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0006631///fatty acid metabolic process+++GO:0006629///lipid metabolic process","MORC family CW-type zinc finger 2","[MORC2_HUMAN|Reviewed]RecName: Full=MORC family CW-type zinc finger protein 2; AltName: Full=Zinc finger CW-type coiled-coil domain protein 1;+++[H7C1V1_HUMAN|Unreviewed]SubName: Full=MORC family CW-type zinc finger protein 2 {ECO:0000313|Ensembl:ENSP00000402602}; Flags: Fragment;+++[H7C3M1_HUMAN|Unreviewed]SubName: Full=MORC family CW-type zinc finger protein 2 {ECO:0000313|Ensembl:ENSP00000412685}; Flags: Fragment;"]
[2289,"'FKBP5'",180,149,215,181.333333333333,"04915///Estrogen signaling pathway","H01646///Major depressive disorder (MDD)",null,null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding","GO:0006457///protein folding+++GO:0009617///response to bacterium+++GO:0061077///chaperone-mediated protein folding+++GO:0000413///protein peptidyl-prolyl isomerization","FK506 binding protein 5","[FKBP5_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP5; Short=PPIase FKBP5; EC=5.2.1.8; AltName: Full=51 kDa FK506-binding protein; Short=51 kDa FKBP; Short=FKBP-51; AltName: Full=54 kDa progesterone receptor-associated immunophilin; AltName: Full=Androgen-regulated protein 6; AltName: Full=FF1 antigen; AltName: Full=FK506-binding protein 5; Short=FKBP-5; AltName: Full=FKBP54; Short=p54; AltName: Full=HSP90-binding immunophilin; AltName: Full=Rotamase;+++[L0R859_HUMAN|Unreviewed]SubName: Full=Alternative protein FKBP5 {ECO:0000313|EMBL:CCO13731.1};+++[L8EC85_HUMAN|Unreviewed]SubName: Full=Alternative protein FKBP5 {ECO:0000313|EMBL:CCQ43127.1};+++[Q2TA84_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};"]
[22901,"'ARSG'",553,547,595,565,"04142///Lysosome",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0005764///lysosome+++GO:0005788///endoplasmic reticulum lumen","GO:0003824///catalytic activity+++GO:0008484///sulfuric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0004065///arylsulfatase activity+++GO:0046872///metal ion binding","GO:0006790///sulfur compound metabolic process","arylsulfatase G","[ARSG_HUMAN|Reviewed]RecName: Full=Arylsulfatase G; Short=ASG; EC=3.1.6.-; Flags: Precursor;+++[A0A024R8K1_HUMAN|Unreviewed]SubName: Full=Arylsulfatase G, isoform CRA_a {ECO:0000313|EMBL:EAW89056.1};+++[J3KS49_HUMAN|Unreviewed]SubName: Full=Arylsulfatase G {ECO:0000313|Ensembl:ENSP00000462306}; Flags: Fragment;+++[J9JIG6_HUMAN|Unreviewed]SubName: Full=Arylsulfatase G {ECO:0000313|Ensembl:ENSP00000413953};"]
[22931,"'RAB18'",1044,900,865,936.333333333333,null,"H00792///Warburg micro syndrome",null,null,"GO:0045202///synapse+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005789///endoplasmic reticulum membrane+++GO:0030667///secretory granule membrane+++GO:0071782///endoplasmic reticulum tubular network","GO:0005515///protein binding+++GO:0019003///GDP binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity","GO:0051170///import into nucleus+++GO:0006886///intracellular protein transport+++GO:0032482///Rab protein signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0007275///multicellular organism development+++GO:0007420///brain development+++GO:0015031///protein transport+++GO:0001654///eye development+++GO:0043312///neutrophil degranulation+++GO:0034389///lipid droplet organization","RAB18, member RAS oncogene family","[RAB18_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-18; Flags: Precursor;+++[A0A087X163_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-18 {ECO:0000313|Ensembl:ENSP00000483927};+++[B7Z4P9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51678, highly similar to Ras-related protein Rab-18 {ECO:0000313|EMBL:BAH12635.1};+++[B7Z5V3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53088, highly similar to Ras-related protein Rab-18 {ECO:0000313|EMBL:BAH13039.1};+++[H0Y6T8_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-18 {ECO:0000313|Ensembl:ENSP00000407872}; Flags: Fragment;+++[Q5W0J0_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-18 {ECO:0000313|Ensembl:ENSP00000364960};"]
[22944,"'KIN'",166.16,121.3,128.08,138.513333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016363///nuclear matrix+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding","GO:0006310///DNA recombination+++GO:0006281///DNA repair+++GO:0016032///viral process+++GO:0006260///DNA replication+++GO:0006397///mRNA processing+++GO:0006974///cellular response to DNA damage stimulus","Kin17 DNA and RNA binding protein","[KIN17_HUMAN|Reviewed]RecName: Full=DNA/RNA-binding protein KIN17; AltName: Full=Binding to curved DNA; AltName: Full=KIN, antigenic determinant of recA protein homolog;+++[S4R357_HUMAN|Unreviewed]SubName: Full=DNA/RNA-binding protein KIN17 {ECO:0000313|Ensembl:ENSP00000473950}; Flags: Fragment;"]
[22987,"'SV2C'",0,3,5,2.66666666666667,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0008021///synaptic vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0030672///synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030054///cell junction+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity+++GO:0005215///transporter activity","GO:0006836///neurotransmitter transport+++GO:0055085///transmembrane transport+++GO:0007268///chemical synaptic transmission","synaptic vesicle glycoprotein 2C","[SV2C_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2C;+++[B3KT41_HUMAN|Unreviewed]SubName: Full=cDNA FLJ37598 fis, clone BRCOC2008642, highly similar to Synaptic vesicle glycoprotein 2C {ECO:0000313|EMBL:BAG52953.1};"]
[23,"'ABCF1'",1710,1677,1484,1623.66666666667,{"$nulls":4},"GO:0005635///nuclear envelope+++GO:0042788///polysomal ribosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005840///ribosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0016887///ATPase activity+++GO:0043022///ribosome binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding+++GO:0008494///translation activator activity+++GO:0005524///ATP binding+++GO:0003723///RNA binding","GO:0055085///transmembrane transport+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0042254///ribosome biogenesis+++GO:0006954///inflammatory response+++GO:0045727///positive regulation of translation","ATP binding cassette subfamily F member 1","[ABCF1_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family F member 1; AltName: Full=ATP-binding cassette 50; AltName: Full=TNF-alpha-stimulated ABC protein;+++[A0A0G2JIC2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000397199};+++[A0A1U9X609_HUMAN|Unreviewed]SubName: Full=ABCF1 {ECO:0000313|EMBL:AQY76226.1};+++[A0PJ72_HUMAN|Unreviewed]SubName: Full=ABCF1 protein {ECO:0000313|EMBL:AAH16772.1}; Flags: Fragment;+++[F5GYK6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000440893}; Flags: Fragment;+++[H0YGW7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000445100}; Flags: Fragment;+++[L0R6B8_HUMAN|Unreviewed]SubName: Full=Alternative protein ABCF1 {ECO:0000313|EMBL:CCO13667.1};+++[Q2L6I2_HUMAN|Unreviewed]SubName: Full=ABC50 protein {ECO:0000313|EMBL:BAF31263.1}; SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 1 {ECO:0000313|EMBL:BAE78612.1}; SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 1, isoform CRA_a {ECO:0000313|EMBL:EAX03300.1};+++[Q5STZ8_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000405512}; Flags: Fragment;"]
[23024,"'PDZRN3'",1878,1711,1675,1754.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0031594///neuromuscular junction+++GO:0005654///nucleoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0007528///neuromuscular junction development+++GO:0016567///protein ubiquitination","PDZ domain containing ring finger 3","[PZRN3_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase PDZRN3; EC=2.3.2.27; AltName: Full=Ligand of Numb protein X 3; AltName: Full=PDZ domain-containing RING finger protein 3; AltName: Full=RING-type E3 ubiquitin transferase PDZRN3 {ECO:0000305}; AltName: Full=Semaphorin cytoplasmic domain-associated protein 3; Short=Protein SEMACAP3;+++[B2RWP2_HUMAN|Unreviewed]SubName: Full=PDZ domain containing ring finger 3 {ECO:0000313|EMBL:AAI50624.1};+++[B7Z2I8_HUMAN|Unreviewed]SubName: Full=PDZ domain containing RING finger 3, isoform CRA_a {ECO:0000313|EMBL:EAW65531.1}; SubName: Full=cDNA FLJ54738, highly similar to PDZ domain-containing RING finger protein 3 {ECO:0000313|EMBL:BAH11874.1};+++[B7Z5Q3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54746, highly similar to PDZ domain-containing RING finger protein 3 {ECO:0000313|EMBL:BAH12989.1};+++[B7Z5X9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55043, highly similar to PDZ domain-containing RING finger protein 3 {ECO:0000313|EMBL:BAH13065.1};+++[B7ZAG0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase PDZRN3 {ECO:0000313|Ensembl:ENSP00000418624}; SubName: Full=cDNA, FLJ79174, highly similar to PDZ domain-containing RING finger protein 3 {ECO:0000313|EMBL:BAH14646.1};+++[C9JWE6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase PDZRN3 {ECO:0000313|Ensembl:ENSP00000419250}; Flags: Fragment;+++[E7ENB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase PDZRN3 {ECO:0000313|Ensembl:ENSP00000418484};+++[H7C566_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase PDZRN3 {ECO:0000313|Ensembl:ENSP00000419095}; Flags: Fragment;+++[L8E852_HUMAN|Unreviewed]SubName: Full=Alternative protein PDZRN3 {ECO:0000313|EMBL:CCQ43480.1};"]
[23036,"'ZNF292'",391,264,316,323.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0045944///positive regulation of transcription by RNA polymerase II","zinc finger protein 292","[ZN292_HUMAN|Reviewed]RecName: Full=Zinc finger protein 292;+++[E5RFE6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 292 {ECO:0000313|Ensembl:ENSP00000428925}; Flags: Fragment;+++[E5RJG2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 292 {ECO:0000313|Ensembl:ENSP00000430569};+++[H0YAU0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 292 {ECO:0000313|Ensembl:ENSP00000428073}; Flags: Fragment;+++[H0YB79_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 292 {ECO:0000313|Ensembl:ENSP00000428857}; Flags: Fragment;+++[J3KNV1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 292 {ECO:0000313|Ensembl:ENSP00000342847};+++[Q3LIB3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla00365 {ECO:0000313|EMBL:BAE45755.1}; Flags: Fragment;+++[Q6P495_HUMAN|Unreviewed]SubName: Full=ZNF292 protein {ECO:0000313|EMBL:AAH63594.1}; Flags: Fragment;"]
[23060,"'ZNF609'",1315,1027,1177,1173,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00511///Short rib-polydactyly syndrome+++H02157///Short-rib thoracic dysplasia",null,null,"GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:2000291///regulation of myoblast proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:2001224///positive regulation of neuron migration+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 609","[ZN609_HUMAN|Reviewed]RecName: Full=Zinc finger protein 609 {ECO:0000312|HGNC:HGNC:29003};+++[A5PKW6_HUMAN|Unreviewed]SubName: Full=ZNF609 protein {ECO:0000313|EMBL:AAI42648.1};+++[E7ERY8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 609 {ECO:0000313|Ensembl:ENSP00000388846};+++[L8ECF6_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF609 {ECO:0000313|EMBL:CCQ43482.1};"]
[23075,"'SWAP70'",432.94,386,350,389.646666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0045296///cadherin binding+++GO:0003677///DNA binding+++GO:0005509///calcium ion binding","GO:0051017///actin filament bundle assembly+++GO:0032233///positive regulation of actin filament bundle assembly+++GO:0045190///isotype switching+++GO:0016444///somatic cell DNA recombination+++GO:1902309///negative regulation of peptidyl-serine dephosphorylation+++GO:0032880///regulation of protein localization+++GO:0030835///negative regulation of actin filament depolymerization+++GO:0033633///negative regulation of cell-cell adhesion mediated by integrin+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008064///regulation of actin polymerization or depolymerization","switching B cell complex subunit SWAP70","[SWP70_HUMAN|Reviewed]RecName: Full=Switch-associated protein 70; Short=SWAP-70;+++[B3KUB9_HUMAN|Unreviewed]SubName: Full=SWAP-70 protein, isoform CRA_b {ECO:0000313|EMBL:EAW68584.1}; SubName: Full=cDNA FLJ39540 fis, clone PUAEN2008314, highly similar to Switch-associated protein 70 {ECO:0000313|EMBL:BAG53381.1};+++[E7EMB1_HUMAN|Unreviewed]SubName: Full=Switch-associated protein 70 {ECO:0000313|Ensembl:ENSP00000399056};+++[E9PJK8_HUMAN|Unreviewed]SubName: Full=Switch-associated protein 70 {ECO:0000313|Ensembl:ENSP00000431768};+++[E9PJM7_HUMAN|Unreviewed]SubName: Full=Switch-associated protein 70 {ECO:0000313|Ensembl:ENSP00000435587}; Flags: Fragment;+++[H0YDK5_HUMAN|Unreviewed]SubName: Full=Switch-associated protein 70 {ECO:0000313|Ensembl:ENSP00000433824}; Flags: Fragment;"]
[23095,"'KIF1B'",1261.98,899.34,1085,1082.10666666667,null,"H01351///Spastic ataxia (SPAX)+++H00773///Autosomal dominant mental retardation+++H00264///Charcot-Marie-Tooth disease (CMT)+++H00265///Hereditary sensory and autonomic neuropathy (HSAN)",null,null,"GO:0005739///mitochondrion+++GO:0005871///kinesin complex+++GO:0030425///dendrite+++GO:0030424///axon+++GO:1904115///axon cytoplasm+++GO:0005875///microtubule associated complex+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:1990939///ATP-dependent microtubule motor activity+++GO:0019894///kinesin binding+++GO:0005524///ATP binding+++GO:0097110///scaffold protein binding+++GO:0016887///ATPase activity+++GO:0003774///motor activity+++GO:0008017///microtubule binding+++GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity","GO:1904647///response to rotenone+++GO:0007018///microtubule-based movement+++GO:0032418///lysosome localization+++GO:0006915///apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0047497///mitochondrion transport along microtubule+++GO:0008089///anterograde axonal transport+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0016192///vesicle-mediated transport+++GO:1990778///protein localization to cell periphery+++GO:0007270///neuron-neuron synaptic transmission+++GO:0010970///transport along microtubule+++GO:1990048///anterograde neuronal dense core vesicle transport+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0007274///neuromuscular synaptic transmission+++GO:1990049///retrograde neuronal dense core vesicle transport","kinesin family member 1B","[KIF1B_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF1B; Short=Klp;+++[A0A024R4H4_HUMAN|Unreviewed]SubName: Full=Kinesin family member 1B, isoform CRA_b {ECO:0000313|EMBL:EAW71643.1};+++[A0A087WWA3_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF1B {ECO:0000313|Ensembl:ENSP00000480063};+++[A0A0U1RQL3_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF1B {ECO:0000313|Ensembl:ENSP00000489057}; Flags: Fragment;+++[Q4R9M9_HUMAN|Unreviewed]SubName: Full=Kinesin family member 1Bbeta isoform II {ECO:0000313|EMBL:BAE02544.1}; SubName: Full=Kinesin-like protein KIF1B {ECO:0000313|Ensembl:ENSP00000478500};"]
[23114,"'NFASC'",5241,4572,4696,4836.33333333333,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0030424///axon+++GO:0043194///axon initial segment+++GO:0033268///node of Ranvier+++GO:0016020///membrane+++GO:0097454///Schwann cell microvillus+++GO:0033270///paranode region of axon+++GO:0043209///myelin sheath+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0005925///focal adhesion+++GO:0016021///integral component of membrane+++GO:0033010///paranodal junction+++GO:0101003///ficolin-1-rich granule membrane","GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0086080///protein binding involved in heterotypic cell-cell adhesion","GO:0050808///synapse organization+++GO:0071205///protein localization to juxtaparanode region of axon+++GO:0043312///neutrophil degranulation+++GO:0002175///protein localization to paranode region of axon+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0030913///paranodal junction assembly+++GO:0034113///heterotypic cell-cell adhesion+++GO:0019226///transmission of nerve impulse+++GO:0007422///peripheral nervous system development+++GO:0042552///myelination+++GO:0007411///axon guidance+++GO:0072659///protein localization to plasma membrane+++GO:0007155///cell adhesion","neurofascin","[NFASC_HUMAN|Reviewed]RecName: Full=Neurofascin; Flags: Precursor;+++[A0A0C4DG92_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000416891}; Flags: Fragment;+++[B4DRH7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61350, highly similar to Neurofascin {ECO:0000313|EMBL:BAG61289.1};+++[D6RBU5_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000422524};+++[D6RHX4_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000427586}; Flags: Fragment;+++[H7BY57_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000356141}; Flags: Fragment;+++[H7C073_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000393290}; Flags: Fragment;+++[H7C0L6_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000395664}; Flags: Fragment;+++[X6RKN2_HUMAN|Unreviewed]SubName: Full=Neurofascin {ECO:0000313|Ensembl:ENSP00000415031}; Flags: Fragment;"]
[23135,"'KDM6B'",1525,1403,1583,1503.66666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0044666///MLL3/4 complex+++GO:0005634///nucleus","GO:0051213///dioxygenase activity+++GO:0032452///histone demethylase activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0008013///beta-catenin binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding","GO:0021766///hippocampus development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0060992///response to fungicide+++GO:0014823///response to activity+++GO:0071557///histone H3-K27 demethylation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0016577///histone demethylation+++GO:0006338///chromatin remodeling+++GO:0045165///cell fate commitment+++GO:0055007///cardiac muscle cell differentiation+++GO:0006325///chromatin organization+++GO:0045446///endothelial cell differentiation+++GO:0010468///regulation of gene expression+++GO:0055114///oxidation-reduction process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0048333///mesodermal cell differentiation+++GO:0006954///inflammatory response","lysine demethylase 6B","[KDM6B_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 6B; EC=1.14.11.- {ECO:0000269|PubMed:17713478, ECO:0000269|PubMed:17825402, ECO:0000269|PubMed:17851529, ECO:0000269|PubMed:18003914}; AltName: Full=JmjC domain-containing protein 3; AltName: Full=Jumonji domain-containing protein 3; AltName: Full=Lysine demethylase 6B;+++[I3L0Z0_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 6B {ECO:0000313|Ensembl:ENSP00000458445}; Flags: Fragment;"]
[23151,"'GRAMD4'",739,626,819,728,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane","GO:0003674///molecular_function","GO:0006915///apoptotic process+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process","GRAM domain containing 4","[GRAM4_HUMAN|Reviewed]RecName: Full=GRAM domain-containing protein 4; AltName: Full=Death-inducing protein;+++[H0Y5A3_HUMAN|Unreviewed]SubName: Full=GRAM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000397501}; Flags: Fragment;+++[X6RHZ2_HUMAN|Unreviewed]SubName: Full=GRAM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000408042}; Flags: Fragment;+++[X6RIP6_HUMAN|Unreviewed]SubName: Full=GRAM domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000409784}; Flags: Fragment;"]
[23169,"'SLC35D1'",224,163,156,181,null,"H00474///Schneckenbecken dysplasia",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0005461///UDP-glucuronic acid transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity","GO:0015787///UDP-glucuronic acid transmembrane transport+++GO:0006065///UDP-glucuronate biosynthetic process+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport+++GO:0008643///carbohydrate transport+++GO:0048706///embryonic skeletal system development+++GO:0030206///chondroitin sulfate biosynthetic process","solute carrier family 35 member D1","[S35D1_HUMAN|Reviewed]RecName: Full=UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; Short=UDP-GlcA/UDP-GalNAc transporter; AltName: Full=Solute carrier family 35 member D1; AltName: Full=UDP-galactose transporter-related protein 7; Short=UGTrel7;"]
[23184,"'MESD'",1390,1246,1172,1269.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005575///cellular_component","GO:0042802///identical protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0003674///molecular_function","GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:0016055///Wnt signaling pathway+++GO:0006457///protein folding+++GO:0007498///mesoderm development+++GO:0034394///protein localization to cell surface+++GO:0006909///phagocytosis","mesoderm development LRP chaperone","[MESD_HUMAN|Reviewed]RecName: Full=LRP chaperone MESD {ECO:0000305}; AltName: Full=LDLR chaperone MESD; AltName: Full=Mesoderm development LRP chaperone MESD {ECO:0000312|HGNC:HGNC:13520}; AltName: Full=Mesoderm development candidate 2; AltName: Full=Mesoderm development protein; AltName: Full=Renal carcinoma antigen NY-REN-61; Flags: Precursor;+++[H0YLI4_HUMAN|Unreviewed]SubName: Full=LRP chaperone MESD {ECO:0000313|Ensembl:ENSP00000453220};"]
[23186,"'RCOR1'",851,573,579,667.666666666667,"05016///Huntington's disease",{"$nulls":3},"GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:1990391///DNA repair complex+++GO:0005667///transcription factor complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0004407///histone deacetylase activity+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0006325///chromatin organization+++GO:0016032///viral process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0070933///histone H4 deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007596///blood coagulation","REST corepressor 1","[RCOR1_HUMAN|Reviewed]RecName: Full=REST corepressor 1; AltName: Full=Protein CoREST;+++[H0YNY4_HUMAN|Unreviewed]SubName: Full=REST corepressor 1 {ECO:0000313|Ensembl:ENSP00000454204}; Flags: Fragment;+++[L0R8D2_HUMAN|Unreviewed]SubName: Full=Alternative protein RCOR1 {ECO:0000313|EMBL:CCO13801.1};"]
[23219,"'FBXO28'",381,296,386,354.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore","GO:0005515///protein binding",null,"F-box protein 28","[FBX28_HUMAN|Reviewed]RecName: Full=F-box only protein 28;+++[A0A024R3Q6_HUMAN|Unreviewed]SubName: Full=F-box protein 28, isoform CRA_a {ECO:0000313|EMBL:EAW69710.1};+++[B4E0H5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50331, highly similar to F-box only protein 28 {ECO:0000313|EMBL:BAG64437.1};"]
[23221,"'RHOBTB2'",761,737.63,940.9,813.176666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0019901///protein kinase binding","GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007264///small GTPase mediated signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0000902///cell morphogenesis+++GO:0031532///actin cytoskeleton reorganization+++GO:0016477///cell migration+++GO:0043652///engulfment of apoptotic cell","Rho related BTB domain containing 2","[RHBT2_HUMAN|Reviewed]RecName: Full=Rho-related BTB domain-containing protein 2; AltName: Full=Deleted in breast cancer 2 gene protein; AltName: Full=p83;+++[E5RI44_HUMAN|Unreviewed]SubName: Full=Rho-related BTB domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000430785}; Flags: Fragment;"]
[23237,"'ARC'",16,21,26,21,"05031///Amphetamine addiction",{"$nulls":3},"GO:0031901///early endosome membrane+++GO:0098839///postsynaptic density membrane+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:1903561///extracellular vesicle+++GO:0005938///cell cortex+++GO:0098845///postsynaptic endosome+++GO:0045121///membrane raft+++GO:0001669///acrosomal vesicle+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0015629///actin cytoskeleton","GO:0003729///mRNA binding","GO:0060997///dendritic spine morphogenesis+++GO:0007010///cytoskeleton organization+++GO:0007612///learning+++GO:0016477///cell migration+++GO:0007492///endoderm development+++GO:0048168///regulation of neuronal synaptic plasticity+++GO:1900271///regulation of long-term synaptic potentiation+++GO:0060291///long-term synaptic potentiation+++GO:0006897///endocytosis+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0007616///long-term memory+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0051028///mRNA transport+++GO:2000969///positive regulation of AMPA receptor activity+++GO:1900452///regulation of long-term synaptic depression+++GO:0022604///regulation of cell morphogenesis+++GO:0110077///vesicle-mediated intercellular transport+++GO:0009952///anterior/posterior pattern specification+++GO:0051260///protein homooligomerization","activity regulated cytoskeleton associated protein","[ARC_HUMAN|Reviewed]RecName: Full=Activity-regulated cytoskeleton-associated protein {ECO:0000303|PubMed:10970730}; Short=hArc {ECO:0000303|PubMed:25748042}; AltName: Full=Activity-regulated gene 3.1 protein homolog {ECO:0000250|UniProtKB:Q9WV31}; Short=ARC/ARG3.1 {ECO:0000250|UniProtKB:Q9WV31}; Short=Arg3.1 {ECO:0000250|UniProtKB:Q9WV31};"]
[23258,"'DENND5A'",966,872,832,890,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00606///Early infantile epileptic encephalopathy",null,null,"GO:0005829///cytosol+++GO:0005802///trans-Golgi network+++GO:0000139///Golgi membrane+++GO:0030904///retromer complex+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017137///Rab GTPase binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0010977///negative regulation of neuron projection development+++GO:0042147///retrograde transport, endosome to Golgi","DENN domain containing 5A","[DEN5A_HUMAN|Reviewed]RecName: Full=DENN domain-containing protein 5A; AltName: Full=Rab6-interacting protein 1; Short=Rab6IP1;+++[B4DFB6_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000436780}; SubName: Full=cDNA FLJ58453, highly similar to Rab6-interacting protein 1 {ECO:0000313|EMBL:BAG57377.1};+++[E9PIS3_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000433925};+++[H0YCW5_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000432428}; Flags: Fragment;+++[H0YDE6_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000433483}; Flags: Fragment;+++[H0YDS8_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000434237}; Flags: Fragment;+++[H0YDV6_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000434397}; Flags: Fragment;+++[H0YE63_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000435038}; Flags: Fragment;+++[H0YEA8_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 5A {ECO:0000313|Ensembl:ENSP00000435368}; Flags: Fragment;"]
[23271,"'CAMSAP2'",1336,817,1132,1095,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005874///microtubule+++GO:0005829///cytosol+++GO:1990752///microtubule end+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0036449///microtubule minus-end+++GO:0005737///cytoplasm+++GO:0005813///centrosome","GO:0008017///microtubule binding+++GO:0051011///microtubule minus-end binding+++GO:0030507///spectrin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding","GO:0031175///neuron projection development+++GO:0050773///regulation of dendrite development+++GO:0061564///axon development+++GO:0033043///regulation of organelle organization+++GO:0031122///cytoplasmic microtubule organization+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0031113///regulation of microtubule polymerization+++GO:1903358///regulation of Golgi organization+++GO:0000226///microtubule cytoskeleton organization","calmodulin regulated spectrin associated protein family member 2","[CAMP2_HUMAN|Reviewed]RecName: Full=Calmodulin-regulated spectrin-associated protein 2 {ECO:0000305}; AltName: Full=Calmodulin-regulated spectrin-associated protein 1-like protein 1;+++[B3KTI4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38321 fis, clone FCBBF3024225, highly similar to Homo sapiens calmodulin regulated spectrin-associated protein 1-like 1 (CAMSAP1L1), mRNA {ECO:0000313|EMBL:BAG53096.1}; Flags: Fragment;+++[H0Y4Z1_HUMAN|Unreviewed]SubName: Full=Calmodulin-regulated spectrin-associated protein 2 {ECO:0000313|Ensembl:ENSP00000395365}; Flags: Fragment;+++[H0YE13_HUMAN|Unreviewed]SubName: Full=Calmodulin-regulated spectrin-associated protein 2 {ECO:0000313|Ensembl:ENSP00000434766}; Flags: Fragment;"]
[2330,"'FMO5'",7,6,3,5.33333333333333,"01120///Microbial metabolism in diverse environments+++00982///Drug metabolism - cytochrome P450","H01234///Trimethylaminuria (TMAU)",null,"R08266///tamoxifen,NADPH:oxygen oxidoreductase (N-oxide-forming)   Tamoxifen + Oxygen + NADPH + H+ <=> Tamoxifen N-oxide + NADP+ + H2O","GO:0031090///organelle membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004499///N,N-dimethylaniline monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0004497///monooxygenase activity+++GO:0050661///NADP binding+++GO:0050660///flavin adenine dinucleotide binding","GO:0055114///oxidation-reduction process+++GO:0008150///biological_process","flavin containing monooxygenase 5","[FMO5_HUMAN|Reviewed]RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 5; EC=1.14.13.8; AltName: Full=Dimethylaniline oxidase 5; AltName: Full=Hepatic flavin-containing monooxygenase 5; Short=FMO 5;+++[A0A024QYY6_HUMAN|Unreviewed]RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] {ECO:0000256|PIRNR:PIRNR000332}; EC=1.14.13.8 {ECO:0000256|PIRNR:PIRNR000332};+++[E9PJF3_HUMAN|Unreviewed]RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177}; EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};+++[E9PP51_HUMAN|Unreviewed]SubName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 5 {ECO:0000313|Ensembl:ENSP00000436429}; Flags: Fragment;+++[E9PQ84_HUMAN|Unreviewed]SubName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 5 {ECO:0000313|Ensembl:ENSP00000432569}; Flags: Fragment;+++[Q9HA79_HUMAN|Unreviewed]RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177}; EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};"]
[2331,"'FMOD'",171,172,130,157.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0043202///lysosomal lumen+++GO:0031012///extracellular matrix","GO:0030021///extracellular matrix structural constituent conferring compression resistance","GO:0042340///keratan sulfate catabolic process+++GO:0030199///collagen fibril organization+++GO:0007181///transforming growth factor beta receptor complex assembly+++GO:0018146///keratan sulfate biosynthetic process","fibromodulin","[FMOD_HUMAN|Reviewed]RecName: Full=Fibromodulin; Short=FM; AltName: Full=Collagen-binding 59 kDa protein; AltName: Full=Keratan sulfate proteoglycan fibromodulin; Short=KSPG fibromodulin; Flags: Precursor;+++[A0A024R971_HUMAN|Unreviewed]SubName: Full=Fibromodulin, isoform CRA_a {ECO:0000313|EMBL:EAW91478.1};+++[B3KS64_HUMAN|Unreviewed]SubName: Full=cDNA FLJ35580 fis, clone SPLEN2006389, highly similar to FIBROMODULIN {ECO:0000313|EMBL:BAG52626.1};+++[Q12833_HUMAN|Unreviewed]SubName: Full=Fibromodulin {ECO:0000313|EMBL:AAA16153.1}; Flags: Fragment;"]
[23335,"'WDR7'",404,290,372,355.333333333333,"01100///Metabolic pathways+++00380///Tryptophan metabolism",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin+++R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate","GO:0008021///synaptic vesicle","GO:0005515///protein binding","GO:0002244///hematopoietic progenitor cell differentiation","WD repeat domain 7","[WDR7_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 7; AltName: Full=Rabconnectin-3 beta; AltName: Full=TGF-beta resistance-associated protein TRAG;+++[A2RRE0_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 7 {ECO:0000313|Ensembl:ENSP00000481823}; SubName: Full=WDR7 protein {ECO:0000313|EMBL:AAI31559.1};+++[K7EMB8_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 7 {ECO:0000313|Ensembl:ENSP00000466438}; Flags: Fragment;+++[K7EMF3_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 7 {ECO:0000313|Ensembl:ENSP00000466480}; Flags: Fragment;+++[K7EPQ4_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 7 {ECO:0000313|Ensembl:ENSP00000467485};+++[K7EPY9_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 7 {ECO:0000313|Ensembl:ENSP00000467596}; Flags: Fragment;"]
[23349,"'PHF24'",5,6,13,8,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0046872///metal ion binding","GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0050966///detection of mechanical stimulus involved in sensory perception of pain","PHD finger protein 24","[PHF24_HUMAN|Reviewed]RecName: Full=PHD finger protein 24 {ECO:0000312|HGNC:HGNC:29180};"]
[23376,"'UFL1'",172,130,129,143.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0043005///neuron projection+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0071568///UFM1 transferase activity+++GO:0005515///protein binding","GO:0008284///positive regulation of cell proliferation+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0060252///positive regulation of glial cell proliferation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032880///regulation of protein localization+++GO:0001649///osteoblast differentiation+++GO:1990592///protein K69-linked ufmylation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:1902065///response to L-glutamate+++GO:0010468///regulation of gene expression+++GO:0071569///protein ufmylation+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0034976///response to endoplasmic reticulum stress","UFM1 specific ligase 1","[UFL1_HUMAN|Reviewed]RecName: Full=E3 UFM1-protein ligase 1 {ECO:0000305}; EC=2.3.2.- {ECO:0000269|PubMed:20018847}; AltName: Full=E3 UFM1-protein transferase 1 {ECO:0000305}; AltName: Full=Novel LZAP-binding protein {ECO:0000303|PubMed:20164180}; AltName: Full=Regulator of C53/LZAP and DDRGK1;"]
[23386,"'NUDCD3'",1055,1075,1009,1046.33333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005868///cytoplasmic dynein complex","GO:0051082///unfolded protein binding+++GO:0005515///protein binding","GO:0060271///cilium assembly+++GO:0006457///protein folding+++GO:1905793///protein localization to pericentriolar material+++GO:0032502///developmental process","NudC domain containing 3","[NUDC3_HUMAN|Reviewed]RecName: Full=NudC domain-containing protein 3;"]
[23414,"'ZFPM2'",65,54,74,64.3333333333333,"05206///MicroRNAs in cancer","H00607///46,XY disorders of sex development (Disorders of gonadal development)+++H01241///Congenital diaphragmatic hernia (CDH)+++H00549///Tetralogy of Fallot",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0003677///DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding","GO:2000020///positive regulation of male gonad development+++GO:0045599///negative regulation of fat cell differentiation+++GO:0007596///blood coagulation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0001701///in utero embryonic development+++GO:0001570///vasculogenesis+++GO:0048568///embryonic organ development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0060412///ventricular septum morphogenesis+++GO:0003221///right ventricular cardiac muscle tissue morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007506///gonadal mesoderm development+++GO:0007507///heart development+++GO:0060548///negative regulation of cell death+++GO:0030324///lung development+++GO:0048738///cardiac muscle tissue development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0003148///outflow tract septum morphogenesis+++GO:2000195///negative regulation of female gonad development","zinc finger protein, FOG family member 2","[FOG2_HUMAN|Reviewed]RecName: Full=Zinc finger protein ZFPM2; AltName: Full=Friend of GATA protein 2; Short=FOG-2; Short=Friend of GATA 2; Short=hFOG-2; AltName: Full=Zinc finger protein 89B; AltName: Full=Zinc finger protein multitype 2;+++[E5RJX0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFPM2 {ECO:0000313|Ensembl:ENSP00000428149}; Flags: Fragment;+++[E7ET52_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFPM2 {ECO:0000313|Ensembl:ENSP00000428720};+++[Q32MA5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein, multitype 2 {ECO:0000313|EMBL:AAI09224.1};+++[Q9NPQ0_HUMAN|Unreviewed]SubName: Full=FOG2, frind of GATA2 {ECO:0000313|EMBL:CAB97540.1}; Flags: Fragment;"]
[23424,"'TDRD7'",212,177,180,189.666666666667,null,"H01202///Cataract",null,null,"GO:0005737///cytoplasm+++GO:0033391///chromatoid body+++GO:0005759///mitochondrial matrix+++GO:0035770///ribonucleoprotein granule","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0047485///protein N-terminus binding","GO:0070306///lens fiber cell differentiation+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0030154///cell differentiation+++GO:0007283///spermatogenesis","tudor domain containing 7","[TDRD7_HUMAN|Reviewed]RecName: Full=Tudor domain-containing protein 7; AltName: Full=PCTAIRE2-binding protein; AltName: Full=Tudor repeat associator with PCTAIRE-2; Short=Trap;"]
[23468,"'CBX5'",1549.42,1497.83,1853.33,1633.52666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005721///pericentric heterochromatin+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000775///chromosome, centromeric region+++GO:0005635///nuclear envelope+++GO:0032991///protein-containing complex+++GO:0035097///histone methyltransferase complex+++GO:0000118///histone deacetylase complex+++GO:0031618///nuclear pericentric heterochromatin+++GO:0000776///kinetochore+++GO:0017053///transcriptional repressor complex+++GO:0010369///chromocenter+++GO:0016605///PML body+++GO:0000792///heterochromatin+++GO:0090734///site of DNA damage+++GO:0005720///nuclear heterochromatin","GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding+++GO:0044877///protein-containing complex binding+++GO:0035064///methylated histone binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0042826///histone deacetylase binding+++GO:0030674///protein binding, bridging+++GO:0070491///repressing transcription factor binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding","GO:0016032///viral process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007596///blood coagulation+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0006974///cellular response to DNA damage stimulus","chromobox 5","[CBX5_HUMAN|Reviewed]RecName: Full=Chromobox protein homolog 5; AltName: Full=Antigen p25; AltName: Full=Heterochromatin protein 1 homolog alpha; Short=HP1 alpha;+++[F8VNY3_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 5 {ECO:0000313|Ensembl:ENSP00000450190}; Flags: Fragment;+++[Q6I9T7_HUMAN|Unreviewed]SubName: Full=CBX5 protein {ECO:0000313|EMBL:CAG33699.1};+++[V9HWG0_HUMAN|Unreviewed]SubName: Full=Chromobox homolog 5 (HP1 alpha homolog, Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW96760.1}; SubName: Full=Epididymis luminal protein 25 {ECO:0000313|EMBL:ACJ13653.1};"]
[23476,"'BRD4'",2434,2217,2525,2392,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0000794///condensed nuclear chromosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005829///cytosol","GO:0099122///RNA polymerase II C-terminal domain binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0070577///lysine-acetylated histone binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0002039///p53 binding+++GO:0019899///enzyme binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:1901407///regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0006468///protein phosphorylation+++GO:0006325///chromatin organization+++GO:0006338///chromatin remodeling+++GO:2001255///positive regulation of histone H3-K36 trimethylation+++GO:0016032///viral process+++GO:0050727///regulation of inflammatory response","bromodomain containing 4","[BRD4_HUMAN|Reviewed]RecName: Full=Bromodomain-containing protein 4; AltName: Full=Protein HUNK1;+++[A0A024R7H8_HUMAN|Unreviewed]SubName: Full=Bromodomain containing 4, isoform CRA_b {ECO:0000313|EMBL:EAW84471.1};+++[M0QYW0_HUMAN|Unreviewed]SubName: Full=Bromodomain containing 4, isoform CRA_c {ECO:0000313|EMBL:EAW84472.1}; SubName: Full=Bromodomain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000470108};+++[M0QZD9_HUMAN|Unreviewed]SubName: Full=Bromodomain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000470481}; Flags: Fragment;+++[M0R0H4_HUMAN|Unreviewed]SubName: Full=Bromodomain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000471240}; Flags: Fragment;+++[Q05BM2_HUMAN|Unreviewed]SubName: Full=BRD4 protein {ECO:0000313|EMBL:AAH38988.1}; Flags: Fragment;+++[Q5BJ26_HUMAN|Unreviewed]SubName: Full=BRD4 protein {ECO:0000313|EMBL:AAH91649.1}; Flags: Fragment;+++[Q6NXE4_HUMAN|Unreviewed]SubName: Full=BRD4 protein {ECO:0000313|EMBL:AAH67129.1}; Flags: Fragment;+++[Q6PIS5_HUMAN|Unreviewed]SubName: Full=BRD4 protein {ECO:0000313|EMBL:AAH30158.1}; Flags: Fragment;+++[W8JJB1_HUMAN|Unreviewed]SubName: Full=Bromodomain-containing protein 4 variant {ECO:0000313|EMBL:AHK61044.1}; Flags: Fragment;"]
[23498,"'HAAO'",35.96,36,44,38.6533333333333,"00380///Tryptophan metabolism+++01100///Metabolic pathways","H02087///Vertebral, cardiac, renal, and limb defects syndrome","M00038///Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate","R02665///3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)   3-Hydroxyanthranilate + Oxygen <=> 2-Amino-3-carboxymuconate semialdehyde","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008198///ferrous iron binding+++GO:0051213///dioxygenase activity+++GO:0005506///iron ion binding+++GO:0000334///3-hydroxyanthranilate 3,4-dioxygenase activity+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0019363///pyridine nucleotide biosynthetic process+++GO:0006569///tryptophan catabolic process+++GO:0019805///quinolinate biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0022900///electron transport chain+++GO:0070050///neuron cellular homeostasis+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan+++GO:0009435///NAD biosynthetic process+++GO:0010043///response to zinc ion+++GO:0046686///response to cadmium ion+++GO:0043420///anthranilate metabolic process+++GO:0046874///quinolinate metabolic process","3-hydroxyanthranilate 3,4-dioxygenase","[3HAO_HUMAN|Reviewed]RecName: Full=3-hydroxyanthranilate 3,4-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03019}; EC=1.13.11.6 {ECO:0000255|HAMAP-Rule:MF_03019, ECO:0000269|PubMed:7514594}; AltName: Full=3-hydroxyanthranilate oxygenase {ECO:0000255|HAMAP-Rule:MF_03019}; Short=3-HAO {ECO:0000255|HAMAP-Rule:MF_03019}; Short=h3HAO {ECO:0000303|PubMed:28375145}; AltName: Full=3-hydroxyanthranilic acid dioxygenase {ECO:0000255|HAMAP-Rule:MF_03019}; Short=HAD {ECO:0000255|HAMAP-Rule:MF_03019};+++[C9IY88_HUMAN|Unreviewed]SubName: Full=3-hydroxyanthranilate 3,4-dioxygenase {ECO:0000313|Ensembl:ENSP00000412601}; Flags: Fragment;"]
[23522,"'KAT6B'",522,376,421,439.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01795///Blepharophimosis-mental retardation syndrome (BMRS)+++H01793///Young-Simpson syndrome+++H01794///Genitopatellar syndrome (GPS)",null,null,"GO:0000786///nucleosome+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0070776///MOZ/MORF histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0000123///histone acetyltransferase complex","GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0016407///acetyltransferase activity+++GO:0004402///histone acetyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0010485///H4 histone acetyltransferase activity","GO:0006334///nucleosome assembly+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016573///histone acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043967///histone H4 acetylation+++GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated","lysine acetyltransferase 6B","[KAT6B_HUMAN|Reviewed]RecName: Full=Histone acetyltransferase KAT6B; EC=2.3.1.48 {ECO:0000269|PubMed:10497217}; AltName: Full=Histone acetyltransferase MOZ2; AltName: Full=MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4; Short=MYST-4; AltName: Full=Monocytic leukemia zinc finger protein-related factor;+++[A7E2B6_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[B2RWN8_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};"]
[23539,"'SLC16A8'",402,319,864,528.333333333333,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015293///symporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0015727///lactate transport+++GO:0035873///lactate transmembrane transport+++GO:0050900///leukocyte migration+++GO:0015718///monocarboxylic acid transport+++GO:0006090///pyruvate metabolic process","solute carrier family 16 member 8","[MOT3_HUMAN|Reviewed]RecName: Full=Monocarboxylate transporter 3; Short=MCT 3; AltName: Full=Solute carrier family 16 member 8;+++[A0A024R1N8_HUMAN|Unreviewed]SubName: Full=Solute carrier 16 (Monocarboxylic acid transporters), member 8, isoform CRA_a {ECO:0000313|EMBL:EAW60215.1};+++[B0QYL4_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 3 {ECO:0000313|Ensembl:ENSP00000409547}; Flags: Fragment;"]
[23560,"'GTPBP4'",495,445,474,471.333333333333,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0043204///perikaryon+++GO:0005829///cytosol","GO:0003924///GTPase activity+++GO:0005344///oxygen carrier activity+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0005525///GTP binding","GO:0033342///negative regulation of collagen binding+++GO:0008285///negative regulation of cell proliferation+++GO:0050821///protein stabilization+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0015671///oxygen transport+++GO:0031397///negative regulation of protein ubiquitination+++GO:0006915///apoptotic process+++GO:0008156///negative regulation of DNA replication+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030336///negative regulation of cell migration+++GO:0042254///ribosome biogenesis+++GO:0001649///osteoblast differentiation","GTP binding protein 4","[NOG1_HUMAN|Reviewed]RecName: Full=Nucleolar GTP-binding protein 1; AltName: Full=Chronic renal failure gene protein; AltName: Full=GTP-binding protein NGB;+++[D2CFK9_HUMAN|Unreviewed]RecName: Full=Nucleolar GTP-binding protein 1 {ECO:0000256|PIRNR:PIRNR038919};+++[Q5T3R7_HUMAN|Unreviewed]SubName: Full=Nucleolar GTP-binding protein 1 {ECO:0000313|Ensembl:ENSP00000353168}; Flags: Fragment;+++[Q8N4P8_HUMAN|Unreviewed]SubName: Full=GTPBP4 protein {ECO:0000313|EMBL:AAH33784.1}; Flags: Fragment;"]
[23588,"'KLHDC2'",465,473,424,454,{"$nulls":4},"GO:0031965///nuclear membrane+++GO:0016604///nuclear body+++GO:0005634///nucleus",null,null,"kelch domain containing 2","[KLDC2_HUMAN|Reviewed]RecName: Full=Kelch domain-containing protein 2; AltName: Full=Hepatocellular carcinoma-associated antigen 33; AltName: Full=Host cell factor homolog LCP; AltName: Full=Host cell factor-like protein 1; Short=HCLP-1;+++[G3V2H2_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000450658};+++[G3V3U8_HUMAN|Unreviewed]SubName: Full=Kelch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000451439};"]
[23608,"'MKRN1'",876,736,811,807.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H02018///Central precocious puberty",null,null,"GO:0005829///cytosol+++GO:0005575///cellular_component","GO:0061630///ubiquitin protein ligase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination","makorin ring finger protein 1","[MKRN1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase makorin-1; EC=2.3.2.27; AltName: Full=RING finger protein 61; AltName: Full=RING-type E3 ubiquitin transferase makorin-1 {ECO:0000305};+++[A1L0W6_HUMAN|Unreviewed]SubName: Full=MKRN1 protein {ECO:0000313|EMBL:AAI27217.1}; Flags: Fragment;+++[C9IY57_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000418864}; Flags: Fragment;+++[C9IZP5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000418620}; Flags: Fragment;+++[C9J031_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000418588}; Flags: Fragment;+++[C9JYI0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000419894};+++[C9JYX8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000419843}; Flags: Fragment;+++[F8WAS8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000417640};+++[F8WBJ4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000417907};+++[F8WEY8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000419695};+++[H7C4H5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000417346}; Flags: Fragment;+++[H7C588_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase makorin-1 {ECO:0000313|Ensembl:ENSP00000419259}; Flags: Fragment;"]
[23639,"'LRRC6'",55,63,77,65,null,"H00564///Primary ciliary dyskinesia",null,null,"GO:0031514///motile cilium+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0005929///cilium","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0036158///outer dynein arm assembly+++GO:0030317///flagellated sperm motility+++GO:0003341///cilium movement+++GO:0044458///motile cilium assembly+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0007010///cytoskeleton organization+++GO:0008584///male gonad development+++GO:0060271///cilium assembly+++GO:0036159///inner dynein arm assembly+++GO:0061458///reproductive system development","leucine rich repeat containing 6","[TILB_HUMAN|Reviewed]RecName: Full=Protein tilB homolog; AltName: Full=Leucine-rich repeat-containing protein 6; AltName: Full=Leucine-rich testis-specific protein; AltName: Full=Testis-specific leucine-rich repeat protein;+++[A0A087X298_HUMAN|Unreviewed]SubName: Full=Protein tilB homolog {ECO:0000313|Ensembl:ENSP00000484802};+++[E5RHF9_HUMAN|Unreviewed]SubName: Full=Protein tilB homolog {ECO:0000313|Ensembl:ENSP00000429811};+++[G5EA20_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat containing 6, isoform CRA_a {ECO:0000313|EMBL:EAW92143.1}; SubName: Full=Protein tilB homolog {ECO:0000313|Ensembl:ENSP00000428610};+++[H0YAS5_HUMAN|Unreviewed]SubName: Full=Protein tilB homolog {ECO:0000313|Ensembl:ENSP00000428015}; Flags: Fragment;+++[H0YBC4_HUMAN|Unreviewed]SubName: Full=Protein tilB homolog {ECO:0000313|Ensembl:ENSP00000429158}; Flags: Fragment;"]
[23660,"'ZKSCAN5'",346,299,273.56,306.186666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008270///zinc ion binding+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger with KRAB and SCAN domains 5","[ZKSC5_HUMAN|Reviewed]RecName: Full=Zinc finger protein with KRAB and SCAN domains 5; AltName: Full=Zinc finger protein 95 homolog; Short=Zfp-95;+++[B3KNK8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14808 fis, clone NT2RP4001790, highly similar to Zinc finger protein 95 homolog {ECO:0000313|EMBL:BAG51370.1};+++[F8WBD4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein with KRAB and SCAN domains 5 {ECO:0000313|Ensembl:ENSP00000405716};+++[J7M2K9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein with KRAB and SCAN domains 5 {ECO:0000313|EMBL:BAM36935.1}; Flags: Fragment;+++[J7M2L3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein with KRAB and SCAN domains 5 {ECO:0000313|EMBL:BAM36945.1}; Flags: Fragment;+++[J7M940_HUMAN|Unreviewed]SubName: Full=Zinc finger protein with KRAB and SCAN domains 5 {ECO:0000313|EMBL:BAM36947.1}; Flags: Fragment;+++[J7ME35_HUMAN|Unreviewed]SubName: Full=Zinc finger protein with KRAB and SCAN domains 5 {ECO:0000313|EMBL:BAM36946.1}; Flags: Fragment;+++[L8EAP2_HUMAN|Unreviewed]SubName: Full=Alternative protein ZKSCAN5 {ECO:0000313|EMBL:CCQ43443.1};+++[Q75MV2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFP95 {ECO:0000313|EMBL:AAS02018.1}; Flags: Fragment;+++[Q8N718_HUMAN|Unreviewed]SubName: Full=ZKSCAN5 protein {ECO:0000313|EMBL:AAH30790.1};"]
[23743,"'BHMT2'",270.54,250,347.86,289.466666666667,"01110///Biosynthesis of secondary metabolites+++00270///Cysteine and methionine metabolism+++01100///Metabolic pathways",null,null,"R00650///S-Adenosyl-L-methionine:L-homocysteine S-methyltransferase   S-Adenosyl-L-methionine + L-Homocysteine <=> S-Adenosyl-L-homocysteine + L-Methionine","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0016740///transferase activity+++GO:0047150///betaine-homocysteine S-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0008168///methyltransferase activity+++GO:0008270///zinc ion binding+++GO:0061627///S-methylmethionine-homocysteine S-methyltransferase activity","GO:0046500///S-adenosylmethionine metabolic process+++GO:0000096///sulfur amino acid metabolic process+++GO:0006577///amino-acid betaine metabolic process+++GO:0032259///methylation+++GO:0033477///S-methylmethionine metabolic process+++GO:0009086///methionine biosynthetic process+++GO:0071267///L-methionine salvage","betaine--homocysteine S-methyltransferase 2","[BHMT2_HUMAN|Reviewed]RecName: Full=S-methylmethionine--homocysteine S-methyltransferase BHMT2; Short=SMM-hcy methyltransferase; EC=2.1.1.10; AltName: Full=Betaine--homocysteine S-methyltransferase 2;+++[A0A024RAQ0_HUMAN|Unreviewed]SubName: Full=Betaine-homocysteine methyltransferase 2, isoform CRA_c {ECO:0000313|EMBL:EAW95830.1};+++[E5RGH5_HUMAN|Unreviewed]SubName: Full=S-methylmethionine--homocysteine S-methyltransferase BHMT2 {ECO:0000313|Ensembl:ENSP00000430155};+++[E5RH96_HUMAN|Unreviewed]SubName: Full=S-methylmethionine--homocysteine S-methyltransferase BHMT2 {ECO:0000313|Ensembl:ENSP00000428640}; Flags: Fragment;"]
[23786,"'BCL2L13'",2224,1973,1813,2003.33333333333,"05134///Legionellosis+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process","GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process","BCL2 like 13","[B2L13_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 13; Short=Bcl2-L-13; AltName: Full=Bcl-rambo; AltName: Full=Protein Mil1;+++[A0A087WTL4_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000477967};+++[A0A087WW80_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000480014};+++[A0A087WX97_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000480836};+++[A0A0A0MR90_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000338932};+++[A8K5Y4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77667, highly similar to Homo sapiens BCL2-like 13 (apoptosis facilitator), mRNA {ECO:0000313|EMBL:BAF84138.1};+++[B2RB43_HUMAN|Unreviewed]SubName: Full=BCL2-like 13 (Apoptosis facilitator), isoform CRA_c {ECO:0000313|EMBL:EAW57768.1}; SubName: Full=cDNA, FLJ95299, highly similar to Homo sapiens BCL2-like 13 (apoptosis facilitator) (BCL2L13),nuclear gene encoding mitochondrial protein, mRNA {ECO:0000313|EMBL:BAG37090.1};+++[B7Z238_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55839, highly similar to Bcl-2-like 13 protein {ECO:0000313|EMBL:BAH11724.1};+++[B7Z737_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52784, highly similar to Bcl-2-like 13 protein {ECO:0000313|EMBL:BAH13473.1};+++[E9PDD6_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000347133};+++[F2Z2C3_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000436321};+++[F6VJB4_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000441344};+++[H0Y3R5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 13 {ECO:0000313|Ensembl:ENSP00000382677}; Flags: Fragment;+++[Q86T62_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451F173 {ECO:0000313|EMBL:CAD89976.1};"]
[24146,"'CLDN15'",69,82,72,74.3333333333333,"05160///Hepatitis C+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++04514///Cell adhesion molecules (CAMs)","H00742///Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome+++H01210///Hypomagnesemia+++H01439///Williams-Beuren syndrome+++H00605///Deafness, autosomal recessive",null,null,"GO:0016020///membrane+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005923///bicellular tight junction","GO:0042802///identical protein binding+++GO:0005198///structural molecule activity","GO:0006811///ion transport+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","claudin 15","[CLD15_HUMAN|Reviewed]RecName: Full=Claudin-15;+++[C9J3Z2_HUMAN|Unreviewed]RecName: Full=Claudin {ECO:0000256|RuleBase:RU060637}; Flags: Fragment;+++[C9JHQ4_HUMAN|Unreviewed]RecName: Full=Claudin {ECO:0000256|RuleBase:RU060637}; Flags: Fragment;+++[H7C2D7_HUMAN|Unreviewed]RecName: Full=Claudin {ECO:0000256|RuleBase:RU060637}; Flags: Fragment;+++[Q96FX9_HUMAN|Unreviewed]RecName: Full=Claudin {ECO:0000256|RuleBase:RU060637};"]
[246330,"'PELI3'",165,181,166,170.666666666667,{"$nulls":4},"GO:0005829///cytosol","GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity","GO:0070498///interleukin-1-mediated signaling pathway+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0006468///protein phosphorylation+++GO:0008063///Toll signaling pathway+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0000209///protein polyubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0016567///protein ubiquitination","pellino E3 ubiquitin protein ligase family member 3","[PELI3_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase pellino homolog 3; Short=Pellino-3; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase pellino homolog 3 {ECO:0000305};+++[A0A024R5B1_HUMAN|Unreviewed]SubName: Full=Pellino homolog 3 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW74536.1};+++[A0A024R5I2_HUMAN|Unreviewed]SubName: Full=Pellino homolog 3 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW74534.1};+++[A1L176_HUMAN|Unreviewed]SubName: Full=PELI3 protein {ECO:0000313|EMBL:AAI27760.1}; Flags: Fragment;+++[E9PI91_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase pellino homolog 3 {ECO:0000313|Ensembl:ENSP00000436722}; Flags: Fragment;+++[E9PQX6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase pellino homolog 3 {ECO:0000313|Ensembl:ENSP00000432449}; Flags: Fragment;+++[E9PR85_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase pellino homolog 3 {ECO:0000313|Ensembl:ENSP00000434314};+++[H0YEM6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase pellino homolog 3 {ECO:0000313|Ensembl:ENSP00000436161}; Flags: Fragment;"]
[2517,"'FUCA1'",1538,1519,1368,1475,"00511///Other glycan degradation","H00422///Glycoproteinoses+++H00141///Fucosidosis",null,null,"GO:0043202///lysosomal lumen+++GO:0005576///extracellular region+++GO:0035578///azurophil granule lumen+++GO:0005764///lysosome+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0004560///alpha-L-fucosidase activity+++GO:0016787///hydrolase activity","GO:0006004///fucose metabolic process+++GO:0008152///metabolic process+++GO:0016139///glycoside catabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006027///glycosaminoglycan catabolic process+++GO:0019377///glycolipid catabolic process+++GO:0043312///neutrophil degranulation","alpha-L-fucosidase 1","[FUCO_HUMAN|Reviewed]RecName: Full=Tissue alpha-L-fucosidase; EC=3.2.1.51; AltName: Full=Alpha-L-fucosidase I; AltName: Full=Alpha-L-fucoside fucohydrolase 1; Short=Alpha-L-fucosidase 1; Flags: Precursor;+++[B5MDC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52780, highly similar to Tissue alpha-L-fucosidase {ECO:0000313|EMBL:BAH13453.1};"]
[253260,"'RICTOR'",422,189,263,291.333333333333,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0031932///TORC2 complex+++GO:0005829///cytosol","GO:0008047///enzyme activator activity+++GO:0019901///protein kinase binding+++GO:0043022///ribosome binding+++GO:0005515///protein binding","GO:0030010///establishment of cell polarity+++GO:0031929///TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0031532///actin cytoskeleton reorganization+++GO:0042325///regulation of phosphorylation+++GO:0016032///viral process+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0001932///regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007275///multicellular organism development+++GO:0051896///regulation of protein kinase B signaling+++GO:0032148///activation of protein kinase B activity+++GO:0018105///peptidyl-serine phosphorylation+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0032956///regulation of actin cytoskeleton organization+++GO:2000114///regulation of establishment of cell polarity+++GO:0050727///regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0010468///regulation of gene expression+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0043087///regulation of GTPase activity","RPTOR independent companion of MTOR complex 2","[RICTR_HUMAN|Reviewed]RecName: Full=Rapamycin-insensitive companion of mTOR; AltName: Full=AVO3 homolog; Short=hAVO3;+++[D6R9S6_HUMAN|Unreviewed]SubName: Full=Rapamycin-insensitive companion of mTOR {ECO:0000313|Ensembl:ENSP00000423162}; Flags: Fragment;+++[Q8N6M7_HUMAN|Unreviewed]SubName: Full=RICTOR protein {ECO:0000313|EMBL:AAH29608.1};"]
[253714,"'MMS22L'",60,42.85,37.27,46.7066666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0042555///MCM complex+++GO:0043596///nuclear replication fork+++GO:0035101///FACT complex","GO:0005515///protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0000724///double-strand break repair via homologous recombination+++GO:0031297///replication fork processing+++GO:0006281///DNA repair","MMS22 like, DNA repair protein","[MMS22_HUMAN|Reviewed]RecName: Full=Protein MMS22-like; AltName: Full=Methyl methanesulfonate-sensitivity protein 22-like;+++[A0A2Z2E9D2_HUMAN|Unreviewed]SubName: Full=MMS22-like DNA repair protein {ECO:0000313|EMBL:APU88434.1};+++[E2QRD4_HUMAN|Unreviewed]SubName: Full=Protein MMS22-like {ECO:0000313|Ensembl:ENSP00000358254};+++[H0Y8J1_HUMAN|Unreviewed]SubName: Full=Protein MMS22-like {ECO:0000313|Ensembl:ENSP00000421225}; Flags: Fragment;+++[H0YAJ2_HUMAN|Unreviewed]SubName: Full=Protein MMS22-like {ECO:0000313|Ensembl:ENSP00000427288}; Flags: Fragment;+++[H9KVD7_HUMAN|Unreviewed]SubName: Full=Protein MMS22-like {ECO:0000313|Ensembl:ENSP00000422045};+++[H9KVD8_HUMAN|Unreviewed]SubName: Full=Protein MMS22-like {ECO:0000313|Ensembl:ENSP00000422627};"]
[254173,"'TTLL10'",0,1,0,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005813///centrosome","GO:0016874///ligase activity+++GO:0005524///ATP binding+++GO:0070740///tubulin-glutamic acid ligase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0070735///protein-glycine ligase activity","GO:0018095///protein polyglutamylation+++GO:0006464///cellular protein modification process+++GO:0060041///retina development in camera-type eye+++GO:0018094///protein polyglycylation","tubulin tyrosine ligase like 10","[TTL10_HUMAN|Reviewed]RecName: Full=Inactive polyglycylase TTLL10; AltName: Full=Tubulin--tyrosine ligase-like protein 10;+++[A0A087WUG0_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL5 {ECO:0000313|Ensembl:ENSP00000478640}; Flags: Fragment;+++[A0PJ69_HUMAN|Unreviewed]SubName: Full=TTLL5 protein {ECO:0000313|EMBL:AAH16625.1}; Flags: Fragment;+++[G3V2J9_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL5 {ECO:0000313|Ensembl:ENSP00000450713};+++[G3V4R8_HUMAN|Unreviewed]SubName: Full=Tubulin polyglutamylase TTLL5 {ECO:0000313|Ensembl:ENSP00000451946};+++[J3QRK8_HUMAN|Unreviewed]SubName: Full=Inactive polyglycylase TTLL10 {ECO:0000313|Ensembl:ENSP00000464269}; Flags: Fragment;+++[Q2TAY9_HUMAN|Unreviewed]SubName: Full=TTLL5 protein {ECO:0000313|EMBL:AAI10653.1}; SubName: Full=Tubulin polyglutamylase TTLL5 {ECO:0000313|Ensembl:ENSP00000451917};"]
[254528,"'MEIOB'",0,1,0,0.333333333333333,null,"H01282///Spermatogenic failure",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005694///chromosome","GO:0003677///DNA binding+++GO:0004518///nuclease activity+++GO:0003697///single-stranded DNA binding+++GO:0016787///hydrolase activity+++GO:0003682///chromatin binding+++GO:0004527///exonuclease activity+++GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity","GO:0007140///male meiotic nuclear division+++GO:0007144///female meiosis I+++GO:0009566///fertilization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007141///male meiosis I+++GO:0007129///synapsis+++GO:0000724///double-strand break repair via homologous recombination+++GO:0000712///resolution of meiotic recombination intermediates+++GO:0051321///meiotic cell cycle","meiosis specific with OB domains","[MEIOB_HUMAN|Reviewed]RecName: Full=Meiosis-specific with OB domain-containing protein; EC=3.1.-.-;+++[H3BSU6_HUMAN|Unreviewed]SubName: Full=Meiosis-specific with OB domain-containing protein {ECO:0000313|Ensembl:ENSP00000456880}; Flags: Fragment;+++[H3BU10_HUMAN|Unreviewed]SubName: Full=Meiosis-specific with OB domain-containing protein {ECO:0000313|Ensembl:ENSP00000457416};+++[H3BU18_HUMAN|Unreviewed]SubName: Full=Meiosis-specific with OB domain-containing protein {ECO:0000313|Ensembl:ENSP00000457427};"]
[2548,"'GAA'",3980,4157,4014,4050.33333333333,"04142///Lysosome+++00052///Galactose metabolism+++01100///Metabolic pathways+++00500///Starch and sucrose metabolism","H01940///Glycogen storage disease type II+++H00069///Glycogen storage diseases (GSD)+++H01762///Muscle glycogen storage disease",null,"R00802///sucrose alpha-glucohydrolase   Sucrose + H2O <=> beta-D-Fructose + alpha-D-Glucose+++R00801///sucrose glucohydrolase   Sucrose + H2O <=> D-Fructose + D-Glucose+++R00028///maltose glucohydrolase   Maltose + H2O <=> 2 D-Glucose","GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0070821///tertiary granule membrane+++GO:0035577///azurophil granule membrane+++GO:0043202///lysosomal lumen+++GO:0101003///ficolin-1-rich granule membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0003824///catalytic activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004558///alpha-1,4-glucosidase activity+++GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0090599///alpha-glucosidase activity+++GO:0032450///maltose alpha-glucosidase activity","GO:0007626///locomotory behavior+++GO:0005980///glycogen catabolic process+++GO:0009888///tissue development+++GO:0005975///carbohydrate metabolic process+++GO:0002026///regulation of the force of heart contraction+++GO:0060048///cardiac muscle contraction+++GO:0006006///glucose metabolic process+++GO:0005985///sucrose metabolic process+++GO:0050885///neuromuscular process controlling balance+++GO:0007040///lysosome organization+++GO:0043312///neutrophil degranulation+++GO:0005977///glycogen metabolic process+++GO:0008152///metabolic process+++GO:0046716///muscle cell cellular homeostasis+++GO:0043181///vacuolar sequestering+++GO:0050884///neuromuscular process controlling posture+++GO:0002086///diaphragm contraction+++GO:0003007///heart morphogenesis+++GO:0000023///maltose metabolic process+++GO:0006941///striated muscle contraction","glucosidase alpha, acid","[LYAG_HUMAN|Reviewed]RecName: Full=Lysosomal alpha-glucosidase; EC=3.2.1.20 {ECO:0000269|PubMed:18429042, ECO:0000269|PubMed:1856189, ECO:0000269|PubMed:29061980, ECO:0000269|PubMed:7717400}; AltName: Full=Acid maltase; AltName: Full=Aglucosidase alfa; Contains: RecName: Full=76 kDa lysosomal alpha-glucosidase; Contains: RecName: Full=70 kDa lysosomal alpha-glucosidase; Flags: Precursor;+++[A0A024R8Q1_HUMAN|Unreviewed]SubName: Full=Glucosidase, alpha acid (Pompe disease, glycogen storage disease type II), isoform CRA_a {ECO:0000313|EMBL:EAW89582.1};+++[I3L0S5_HUMAN|Unreviewed]SubName: Full=Lysosomal alpha-glucosidase {ECO:0000313|Ensembl:ENSP00000458306}; Flags: Fragment;+++[I3L2V9_HUMAN|Unreviewed]SubName: Full=Lysosomal alpha-glucosidase {ECO:0000313|Ensembl:ENSP00000459972}; Flags: Fragment;+++[I3L3L3_HUMAN|Unreviewed]SubName: Full=Lysosomal alpha-glucosidase {ECO:0000313|Ensembl:ENSP00000460543}; Flags: Fragment;"]
[255488,"'RNF144B'",229,207,165,200.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000151///ubiquitin ligase complex+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity","GO:0043066///negative regulation of apoptotic process+++GO:0000209///protein polyubiquitination+++GO:0006915///apoptotic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination","ring finger protein 144B","[R144B_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF144B; EC=2.3.2.31 {ECO:0000250|UniProtKB:O60260}; AltName: Full=IBR domain-containing protein 2; AltName: Full=RING finger protein 144B; AltName: Full=p53-inducible RING finger protein;"]
[255743,"'NPNT'",200,164,122,162,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0070062///extracellular exosome+++GO:0034678///integrin alpha8-beta1 complex+++GO:0030485///smooth muscle contractile fiber+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005178///integrin binding","GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007275///multicellular organism development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0007160///cell-matrix adhesion+++GO:0097195///pilomotor reflex+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0030198///extracellular matrix organization+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0045184///establishment of protein localization+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0001657///ureteric bud development+++GO:0030154///cell differentiation+++GO:0033631///cell-cell adhesion mediated by integrin+++GO:2000721///positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation+++GO:0010694///positive regulation of alkaline phosphatase activity+++GO:0007155///cell adhesion","nephronectin","[NPNT_HUMAN|Reviewed]RecName: Full=Nephronectin; AltName: Full=Preosteoblast EGF-like repeat protein with MAM domain; AltName: Full=Protein EGFL6-like; Flags: Precursor;+++[D6RE63_HUMAN|Unreviewed]SubName: Full=Nephronectin {ECO:0000313|Ensembl:ENSP00000426951}; Flags: Fragment;+++[D6RH31_HUMAN|Unreviewed]SubName: Full=Nephronectin {ECO:0000313|Ensembl:ENSP00000426146}; Flags: Fragment;+++[H0Y8M1_HUMAN|Unreviewed]SubName: Full=Nephronectin {ECO:0000313|Ensembl:ENSP00000421480}; Flags: Fragment;+++[H0YA60_HUMAN|Unreviewed]SubName: Full=Nephronectin {ECO:0000313|Ensembl:ENSP00000426219}; Flags: Fragment;+++[H0YAK9_HUMAN|Unreviewed]SubName: Full=Nephronectin {ECO:0000313|Ensembl:ENSP00000427507}; Flags: Fragment;"]
[256394,"'SERPINA11'",1,2,1,1.33333333333333,null,"H01163///Corticosteroid-binding globulin (CBG) deficiency",null,null,"GO:0005615///extracellular space","GO:0004867///serine-type endopeptidase inhibitor activity",null,"serpin family A member 11","[SPA11_HUMAN|Reviewed]RecName: Full=Serpin A11; Flags: Precursor;"]
[256691,"'MAMDC2'",1825.55,1512.65,1231.91,1523.37,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated","MAM domain containing 2","[MAMC2_HUMAN|Reviewed]RecName: Full=MAM domain-containing protein 2; AltName: Full=MAM domain-containing proteoglycan; Short=Mamcan; Flags: Precursor;+++[A0A0G2JQ91_HUMAN|Unreviewed]SubName: Full=MAM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000485495}; Flags: Fragment;"]
[257407,"'C2orf72'",35,30,40,35,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"chromosome 2 open reading frame 72","[CB072_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C2orf72;"]
[25782,"'RAB3GAP2'",511,331,394,412,null,"H00792///Warburg micro syndrome+++H00797///Martsolf syndrome",null,null,"GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm","GO:0030234///enzyme regulator activity+++GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0008047///enzyme activator activity+++GO:0017137///Rab GTPase binding+++GO:0046982///protein heterodimerization activity+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0043087///regulation of GTPase activity+++GO:1903373///positive regulation of endoplasmic reticulum tubular network organization+++GO:1903061///positive regulation of protein lipidation+++GO:2000786///positive regulation of autophagosome assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0097051///establishment of protein localization to endoplasmic reticulum membrane+++GO:0043085///positive regulation of catalytic activity+++GO:0006886///intracellular protein transport","RAB3 GTPase activating non-catalytic protein subunit 2","[RBGPR_HUMAN|Reviewed]RecName: Full=Rab3 GTPase-activating protein non-catalytic subunit; AltName: Full=RGAP-iso; AltName: Full=Rab3 GTPase-activating protein 150 kDa subunit; AltName: Full=Rab3-GAP p150; Short=Rab3-GAP150; AltName: Full=Rab3-GAP regulatory subunit;+++[F8WDJ2_HUMAN|Unreviewed]SubName: Full=Rab3 GTPase-activating protein non-catalytic subunit {ECO:0000313|Ensembl:ENSP00000420156};+++[H7C4Y9_HUMAN|Unreviewed]SubName: Full=Rab3 GTPase-activating protein non-catalytic subunit {ECO:0000313|Ensembl:ENSP00000418560}; Flags: Fragment;"]
[25797,"'QPCT'",239,230,217,228.666666666667,{"$nulls":4},"GO:0035580///specific granule lumen+++GO:1904724///tertiary granule lumen+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:1904813///ficolin-1-rich granule lumen","GO:0046872///metal ion binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0016603///glutaminyl-peptide cyclotransferase activity","GO:0006464///cellular protein modification process+++GO:0043312///neutrophil degranulation+++GO:0017186///peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase","glutaminyl-peptide cyclotransferase","[QPCT_HUMAN|Reviewed]RecName: Full=Glutaminyl-peptide cyclotransferase; EC=2.3.2.5; AltName: Full=Glutaminyl cyclase; Short=QC; Short=sQC; AltName: Full=Glutaminyl-tRNA cyclotransferase; AltName: Full=Glutamyl cyclase; Short=EC; Flags: Precursor;+++[B5MCZ9_HUMAN|Unreviewed]SubName: Full=Glutaminyl-peptide cyclotransferase {ECO:0000313|Ensembl:ENSP00000385391}; Flags: Fragment;+++[C9JS14_HUMAN|Unreviewed]SubName: Full=Glutaminyl-peptide cyclotransferase {ECO:0000313|Ensembl:ENSP00000389227}; Flags: Fragment;"]
[2582,"'GALE'",360,442,441,414.333333333333,"00520///Amino sugar and nucleotide sugar metabolism+++00052///Galactose metabolism+++01100///Metabolic pathways","H00070///Galactosemia+++H02010///Galactose epimerase deficiency","M00361///Nucleotide sugar biosynthesis, eukaryotes+++M00362///Nucleotide sugar biosynthesis, prokaryotes+++M00632///Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P","R00291///UDP-glucose 4-epimerase; UDP-alpha-D-glucose   UDP-glucose <=> UDP-alpha-D-galactose+++R02984///dTDPglucose 4-epimerase   dTDP-glucose <=> dTDP-galactose","GO:0005829///cytosol","GO:0003824///catalytic activity+++GO:0003978///UDP-glucose 4-epimerase activity+++GO:0050662///coenzyme binding+++GO:0003974///UDP-N-acetylglucosamine 4-epimerase activity+++GO:0016853///isomerase activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity","GO:0005975///carbohydrate metabolic process+++GO:0019388///galactose catabolic process+++GO:0006012///galactose metabolic process","UDP-galactose-4-epimerase","[GALE_HUMAN|Reviewed]RecName: Full=UDP-glucose 4-epimerase {ECO:0000303|PubMed:22654673}; EC=5.1.3.2 {ECO:0000269|PubMed:22654673}; AltName: Full=Galactowaldenase; AltName: Full=UDP-N-acetylgalactosamine 4-epimerase {ECO:0000303|PubMed:22654673}; Short=UDP-GalNAc 4-epimerase {ECO:0000303|PubMed:22654673}; AltName: Full=UDP-N-acetylglucosamine 4-epimerase {ECO:0000303|PubMed:22654673}; Short=UDP-GlcNAc 4-epimerase {ECO:0000303|PubMed:22654673}; EC=5.1.3.7 {ECO:0000269|PubMed:22654673}; AltName: Full=UDP-galactose 4-epimerase {ECO:0000303|PubMed:22654673};+++[A0A024RAB7_HUMAN|Unreviewed]SubName: Full=UDP-galactose-4-epimerase, isoform CRA_b {ECO:0000313|EMBL:EAW95088.1};+++[Q5QPP1_HUMAN|Unreviewed]SubName: Full=UDP-glucose 4-epimerase {ECO:0000313|Ensembl:ENSP00000398257}; Flags: Fragment;+++[Q5QPP3_HUMAN|Unreviewed]SubName: Full=UDP-glucose 4-epimerase {ECO:0000313|Ensembl:ENSP00000414719}; Flags: Fragment;+++[Q5QPP4_HUMAN|Unreviewed]SubName: Full=UDP-glucose 4-epimerase {ECO:0000313|Ensembl:ENSP00000398585}; Flags: Fragment;+++[Q5QPP9_HUMAN|Unreviewed]SubName: Full=UDP-glucose 4-epimerase {ECO:0000313|Ensembl:ENSP00000397045}; Flags: Fragment;"]
[25831,"'HECTD1'",1628,1124,1348,1366.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity","GO:0070534///protein K63-linked ubiquitination+++GO:0016567///protein ubiquitination","HECT domain E3 ubiquitin protein ligase 1","[HECD1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase HECTD1; EC=2.3.2.26 {ECO:0000250|UniProtKB:Q69ZR2}; AltName: Full=E3 ligase for inhibin receptor; AltName: Full=EULIR; AltName: Full=HECT domain-containing protein 1; AltName: Full=HECT-type E3 ubiquitin transferase HECTD1;+++[A0A087WVU6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HECTD1 {ECO:0000313|Ensembl:ENSP00000479695}; Flags: Fragment;+++[A0A087X2H1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HECTD1 {ECO:0000313|Ensembl:ENSP00000484981};+++[G3V4V5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HECTD1 {ECO:0000313|Ensembl:ENSP00000452015}; Flags: Fragment;+++[H0YJ72_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HECTD1 {ECO:0000313|Ensembl:ENSP00000450920}; Flags: Fragment;+++[H0YJD4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HECTD1 {ECO:0000313|Ensembl:ENSP00000451260}; Flags: Fragment;+++[H0YJP0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HECTD1 {ECO:0000313|Ensembl:ENSP00000451860}; Flags: Fragment;+++[H0YJV8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HECTD1 {ECO:0000313|Ensembl:ENSP00000452233}; Flags: Fragment;+++[Q5XJ19_HUMAN|Unreviewed]SubName: Full=HECTD1 protein {ECO:0000313|EMBL:AAH83494.1}; Flags: Fragment;+++[Q9BRJ0_HUMAN|Unreviewed]SubName: Full=HECTD1 protein {ECO:0000313|EMBL:AAH06237.2}; Flags: Fragment;"]
[2584,"'GALK1'",228,265,268,253.666666666667,"01100///Metabolic pathways+++00520///Amino sugar and nucleotide sugar metabolism+++00052///Galactose metabolism","H00070///Galactosemia+++H02009///Galactokinase deficiency","M00554///Nucleotide sugar biosynthesis, galactose => UDP-galactose+++M00632///Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P","R01092///ATP:alpha-D-galactose 1-phosphotransferase   ATP + alpha-D-Galactose <=> ADP + alpha-D-Galactose 1-phosphate","GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0000166///nucleotide binding+++GO:0004335///galactokinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0005524///ATP binding+++GO:0005534///galactose binding","GO:0046835///carbohydrate phosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0006012///galactose metabolic process+++GO:0019388///galactose catabolic process+++GO:0016310///phosphorylation+++GO:0033499///galactose catabolic process via UDP-galactose+++GO:0061623///glycolytic process from galactose+++GO:0019402///galactitol metabolic process","galactokinase 1","[GALK1_HUMAN|Reviewed]RecName: Full=Galactokinase; EC=2.7.1.6; AltName: Full=Galactose kinase;+++[C8CHJ5_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|EMBL:ACU65385.1}; EC=2.7.1.6 {ECO:0000313|EMBL:ACU65385.1}; Flags: Fragment;+++[C8CHJ6_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|EMBL:ACU65386.1}; EC=2.7.1.6 {ECO:0000313|EMBL:ACU65386.1}; Flags: Fragment;+++[D0EM88_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|EMBL:ACW83020.1}; EC=2.7.1.6 {ECO:0000313|EMBL:ACW83020.1}; Flags: Fragment;+++[D1MI96_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|EMBL:ACZ34182.1}; EC=2.7.1.6 {ECO:0000313|EMBL:ACZ34182.1}; Flags: Fragment;+++[E5LAN0_HUMAN|Unreviewed]SubName: Full=Galactokinase 1 {ECO:0000313|EMBL:ADR32097.1}; EC=2.7.1.6 {ECO:0000313|EMBL:ADR32097.1}; Flags: Fragment;+++[K7EII7_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|Ensembl:ENSP00000464765}; Flags: Fragment;+++[K7ERJ9_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|Ensembl:ENSP00000468288};+++[K7ERN9_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|Ensembl:ENSP00000468341}; Flags: Fragment;+++[Q71UH7_HUMAN|Unreviewed]SubName: Full=Galactokinase {ECO:0000313|EMBL:AAC35849.1}; Flags: Fragment;+++[V9HWE7_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 19 {ECO:0000313|EMBL:ACJ13664.1};"]
[25878,"'MXRA5'",35633,27126,25551,29436.6666666667,{"$nulls":4},"GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome","GO:0005201///extracellular matrix structural constituent","GO:0071559///response to transforming growth factor beta","matrix remodeling associated 5","[MXRA5_HUMAN|Reviewed]RecName: Full=Matrix-remodeling-associated protein 5; AltName: Full=Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan; Short=Adlican; Flags: Precursor;+++[L8ECG1_HUMAN|Unreviewed]SubName: Full=Alternative protein MXRA5 {ECO:0000313|EMBL:CCQ43507.1};"]
[25885,"'POLR1A'",1754.9,1437.99,1836,1676.29666666667,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00230///Purine metabolism+++03020///RNA polymerase","H01376///Acrofacial dysostosis","M00182///RNA polymerase I, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0000784///nuclear chromosome, telomeric region+++GO:0005662///DNA replication factor A complex+++GO:0005736///RNA polymerase I complex+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0005730///nucleolus+++GO:0090734///site of DNA damage+++GO:0005634///nucleus","GO:0016779///nucleotidyltransferase activity+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0001054///RNA polymerase I activity+++GO:0003684///damaged DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0008270///zinc ion binding+++GO:0003682///chromatin binding+++GO:0016740///transferase activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0043047///single-stranded telomeric DNA binding","GO:0045815///positive regulation of gene expression, epigenetic+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0051321///meiotic cell cycle+++GO:0034502///protein localization to chromosome+++GO:0006351///transcription, DNA-templated+++GO:0006260///DNA replication+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1904750///negative regulation of protein localization to nucleolus+++GO:0006289///nucleotide-excision repair+++GO:0006261///DNA-dependent DNA replication+++GO:0019985///translesion synthesis+++GO:0000723///telomere maintenance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0036297///interstrand cross-link repair+++GO:0006268///DNA unwinding involved in DNA replication+++GO:1900034///regulation of cellular response to heat+++GO:0006284///base-excision repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0007004///telomere maintenance via telomerase+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0070987///error-free translesion synthesis+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0006298///mismatch repair+++GO:0042276///error-prone translesion synthesis+++GO:0006281///DNA repair+++GO:0032201///telomere maintenance via semi-conservative replication","RNA polymerase I subunit A","[RPA1_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase I subunit RPA1; Short=RNA polymerase I subunit A1; EC=2.7.7.6; AltName: Full=A190; AltName: Full=DNA-directed RNA polymerase I largest subunit; AltName: Full=DNA-directed RNA polymerase I subunit A; AltName: Full=RNA polymerase I 194 kDa subunit; Short=RPA194;+++[B7ZKR9_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279}; EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};+++[B9ZVN9_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279}; EC=2.7.7.6 {ECO:0000256|RuleBase:RU004279};+++[F2Z3I7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA1 {ECO:0000313|Ensembl:ENSP00000386423};+++[I3L2M5_HUMAN|Unreviewed]SubName: Full=Replication protein A 70 kDa DNA-binding subunit {ECO:0000313|Ensembl:ENSP00000459788}; Flags: Fragment;+++[I3L4R8_HUMAN|Unreviewed]SubName: Full=Replication protein A 70 kDa DNA-binding subunit {ECO:0000313|Ensembl:ENSP00000461466}; Flags: Fragment;+++[I3L524_HUMAN|Unreviewed]SubName: Full=Replication protein A 70 kDa DNA-binding subunit {ECO:0000313|Ensembl:ENSP00000461733}; Flags: Fragment;+++[Q53T12_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein POLR1A {ECO:0000313|EMBL:AAY24277.1}; Flags: Fragment;+++[Q96AG9_HUMAN|Unreviewed]SubName: Full=POLR1A protein {ECO:0000313|EMBL:AAH17115.2}; Flags: Fragment;"]
[259173,"'ALS2CL'",176,143,147,155.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0007032///endosome organization","ALS2 C-terminal like","[AL2CL_HUMAN|Reviewed]RecName: Full=ALS2 C-terminal-like protein;+++[A0A024R2U1_HUMAN|Unreviewed]SubName: Full=ALS2 C-terminal like, isoform CRA_c {ECO:0000313|EMBL:EAW64778.1};+++[G5E9N5_HUMAN|Unreviewed]SubName: Full=ALS2 C-terminal like, isoform CRA_a {ECO:0000313|EMBL:EAW64775.1}; SubName: Full=ALS2 C-terminal-like protein {ECO:0000313|Ensembl:ENSP00000405335};+++[H7C0M4_HUMAN|Unreviewed]SubName: Full=ALS2 C-terminal-like protein {ECO:0000313|Ensembl:ENSP00000395749}; Flags: Fragment;"]
[259217,"'HSPA12A'",212,161,184,185.666666666667,"01230///Biosynthesis of amino acids+++04140///Autophagy - animal+++04066///HIF-1 signaling pathway+++00680///Methane metabolism+++03018///RNA degradation+++01110///Biosynthesis of secondary metabolites+++01200///Carbon metabolism+++01100///Metabolic pathways+++00010///Glycolysis / Gluconeogenesis+++04137///Mitophagy - animal+++01120///Microbial metabolism in diverse environments+++01130///Biosynthesis of antibiotics","H01762///Muscle glycogen storage disease+++H00069///Glycogen storage diseases (GSD)+++H01310///Multi-minicore disease (MmD)+++H00590///Congenital muscular dystrophies (CMD/MDC)+++H00701///Congenital fiber type disproportion (CFTD)+++H01953///Glycogen storage disease type XIII","M00003///Gluconeogenesis, oxaloacetate => fructose-6P+++M00002///Glycolysis, core module involving three-carbon compounds+++M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate+++M00346///Formaldehyde assimilation, serine pathway+++M00394///RNA degradosome","R00658///2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming) 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O","GO:0070062///extracellular exosome","GO:0000166///nucleotide binding+++GO:0003674///molecular_function+++GO:0005524///ATP binding","GO:0008150///biological_process","heat shock protein family A (Hsp70) member 12A","[HS12A_HUMAN|Reviewed]RecName: Full=Heat shock 70 kDa protein 12A;+++[A0A1B0GTF3_HUMAN|Unreviewed]SubName: Full=Heat shock 70 kDa protein 12A {ECO:0000313|Ensembl:ENSP00000489674};+++[B7Z2M8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54654, highly similar to Heat shock 70 kDa protein 12A {ECO:0000313|EMBL:BAH11914.1};+++[K7ELE6_HUMAN|Unreviewed]SubName: Full=Heat shock 70 kDa protein 12A {ECO:0000313|Ensembl:ENSP00000466041}; Flags: Fragment;+++[K7ENF6_HUMAN|Unreviewed]SubName: Full=Heat shock 70 kDa protein 12A {ECO:0000313|Ensembl:ENSP00000466927}; Flags: Fragment;"]
[25929,"'GEMIN5'",358,259,309,308.666666666667,"03013///RNA transport",null,"M00426///Survival motor neuron (SMN) complex",null,"GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0032797///SMN complex+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0097504///Gemini of coiled bodies+++GO:0034718///SMN-Gemin2 complex+++GO:0034719///SMN-Sm protein complex+++GO:0005829///cytosol","GO:0000340///RNA 7-methylguanosine cap binding+++GO:0030619///U1 snRNA binding+++GO:0005515///protein binding+++GO:0030622///U4atac snRNA binding+++GO:0030621///U4 snRNA binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0043022///ribosome binding+++GO:0017069///snRNA binding","GO:0006412///translation+++GO:0000387///spliceosomal snRNP assembly+++GO:0008380///RNA splicing+++GO:0065003///protein-containing complex assembly+++GO:0006397///mRNA processing+++GO:0051170///import into nucleus+++GO:0006417///regulation of translation+++GO:0000398///mRNA splicing, via spliceosome","gem nuclear organelle associated protein 5","[GEMI5_HUMAN|Reviewed]RecName: Full=Gem-associated protein 5; Short=Gemin5;+++[B7ZLC9_HUMAN|Unreviewed]SubName: Full=GEMIN5 protein {ECO:0000313|EMBL:AAI43725.1};+++[L8E9U3_HUMAN|Unreviewed]SubName: Full=Alternative protein GEMIN5 {ECO:0000313|EMBL:CCQ43511.1};+++[L8ECG2_HUMAN|Unreviewed]SubName: Full=Alternative protein GEMIN5 {ECO:0000313|EMBL:CCQ43512.1};+++[Q58EZ8_HUMAN|Unreviewed]SubName: Full=GEMIN5 protein {ECO:0000313|EMBL:AAH36894.1}; Flags: Fragment;"]
[25946,"'ZNF385A'",1115,1253,1817,1395,{"$nulls":4},"GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0030425///dendrite+++GO:0000790///nuclear chromatin","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0002039///p53 binding","GO:0045600///positive regulation of fat cell differentiation+++GO:0007626///locomotory behavior+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0030220///platelet formation+++GO:0035855///megakaryocyte development+++GO:1902164///positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0007599///hemostasis+++GO:0008298///intracellular mRNA localization+++GO:0070889///platelet alpha granule organization+++GO:2000765///regulation of cytoplasmic translation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010609///mRNA localization resulting in posttranscriptional regulation of gene expression+++GO:0006915///apoptotic process+++GO:0006417///regulation of translation+++GO:0007611///learning or memory","zinc finger protein 385A","[Z385A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 385A; AltName: Full=Hematopoietic zinc finger protein; AltName: Full=Retinal zinc finger protein;+++[A0A024RB56_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385, isoform CRA_b {ECO:0000313|EMBL:EAW96779.1};+++[F8VQ24_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385A {ECO:0000313|Ensembl:ENSP00000450149}; Flags: Fragment;+++[F8VRY0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385A {ECO:0000313|Ensembl:ENSP00000448466}; Flags: Fragment;+++[F8VSJ1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385A {ECO:0000313|Ensembl:ENSP00000448264}; Flags: Fragment;+++[F8VWV6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385A {ECO:0000313|Ensembl:ENSP00000449462}; Flags: Fragment;+++[F8VY43_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385A {ECO:0000313|Ensembl:ENSP00000448754}; Flags: Fragment;+++[H0YI55_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385A {ECO:0000313|Ensembl:ENSP00000448567}; Flags: Fragment;+++[H0YIX3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385A {ECO:0000313|Ensembl:ENSP00000450373}; Flags: Fragment;"]
[2597,"'GAPDH'",100696,113448,101848,105330.666666667,"00710///Carbon fixation in photosynthetic organisms+++05010///Alzheimer's disease+++01230///Biosynthesis of amino acids+++00010///Glycolysis / Gluconeogenesis+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++04066///HIF-1 signaling pathway+++01120///Microbial metabolism in diverse environments+++01130///Biosynthesis of antibiotics+++01200///Carbon metabolism",null,"M00552///D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P+++M00003///Gluconeogenesis, oxaloacetate => fructose-6P+++M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate+++M00308///Semi-phosphorylative Entner-Doudoroff pathway, gluconate => glycerate-3P+++M00002///Glycolysis, core module involving three-carbon compounds+++M00165///Reductive pentose phosphate cycle (Calvin cycle)+++M00166///Reductive pentose phosphate cycle, ribulose-5P => glyceraldehyde-3P","R01061///D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)   D-Glyceraldehyde 3-phosphate + Orthophosphate + NAD+ <=> 3-Phospho-D-glyceroyl phosphate + NADH + H+","GO:0005811///lipid droplet+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0015630///microtubule cytoskeleton+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:1990904///ribonucleoprotein complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0097452///GAIT complex+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005886///plasma membrane","GO:0097718///disordered domain specific binding+++GO:0050661///NADP binding+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0051287///NAD binding+++GO:0004365///glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity+++GO:0008017///microtubule binding+++GO:0035605///peptidyl-cysteine S-nitrosylase activity+++GO:0042802///identical protein binding","GO:0006094///gluconeogenesis+++GO:0051402///neuron apoptotic process+++GO:0000226///microtubule cytoskeleton organization+++GO:0050832///defense response to fungus+++GO:0071346///cellular response to interferon-gamma+++GO:0035606///peptidyl-cysteine S-trans-nitrosylation+++GO:0050821///protein stabilization+++GO:0010951///negative regulation of endopeptidase activity+++GO:0031640///killing of cells of other organism+++GO:0061621///canonical glycolysis+++GO:0052501///positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction+++GO:0017148///negative regulation of translation+++GO:0051873///killing by host of symbiont cells+++GO:0050715///positive regulation of cytokine secretion+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0016241///regulation of macroautophagy","glyceraldehyde-3-phosphate dehydrogenase","[G3P_HUMAN|Reviewed]RecName: Full=Glyceraldehyde-3-phosphate dehydrogenase; Short=GAPDH; EC=1.2.1.12; AltName: Full=Peptidyl-cysteine S-nitrosylase GAPDH; EC=2.6.99.-;+++[Q16768_HUMAN|Unreviewed]SubName: Full=Glyceraldehyde 3-phosphate dehydrogenase {ECO:0000313|EMBL:AAA52519.1}; EC=1.2.1.12 {ECO:0000313|EMBL:AAA52519.1}; Flags: Fragment;+++[Q5ZEY3_HUMAN|Unreviewed]SubName: Full=Glyceraldehyde-3-phosphate dehydrogenase {ECO:0000313|EMBL:CAH59756.1}; EC=1.2.1.12 {ECO:0000313|EMBL:CAH59756.1}; Flags: Fragment;+++[Q5ZEY4_HUMAN|Unreviewed]SubName: Full=Glyceraldehyde-3-phosphate dehydrogenase {ECO:0000313|EMBL:CAH59755.1}; EC=1.2.1.12 {ECO:0000313|EMBL:CAH59755.1}; Flags: Fragment;+++[V9HVZ4_HUMAN|Unreviewed]RecName: Full=Glyceraldehyde-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361160}; EC=1.2.1.12 {ECO:0000256|RuleBase:RU361160};"]
[25992,"'SNED1'",323,263,378,321.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0005509///calcium ion binding","GO:0007160///cell-matrix adhesion","sushi, nidogen and EGF like domains 1","[SNED1_HUMAN|Reviewed]RecName: Full=Sushi, nidogen and EGF-like domain-containing protein 1; AltName: Full=Insulin-responsive sequence DNA-binding protein 1; Short=IRE-BP1; Flags: Precursor;+++[B5MEF5_HUMAN|Unreviewed]SubName: Full=Sushi, nidogen and EGF-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000342992};+++[H7BYY9_HUMAN|Unreviewed]SubName: Full=Sushi, nidogen and EGF-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000384789}; Flags: Fragment;+++[H7C0D4_HUMAN|Unreviewed]SubName: Full=Sushi, nidogen and EGF-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000394324}; Flags: Fragment;+++[H7C1R9_HUMAN|Unreviewed]SubName: Full=Sushi, nidogen and EGF-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000401865}; Flags: Fragment;"]
[26015,"'RPAP1'",522,553,601,558.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0016779///nucleotidyltransferase activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006366///transcription by RNA polymerase II","RNA polymerase II associated protein 1","[RPAP1_HUMAN|Reviewed]RecName: Full=RNA polymerase II-associated protein 1;+++[A8K2F9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77037, highly similar to Homo sapiens RNA polymerase II associated protein 1, mRNA {ECO:0000313|EMBL:BAF82913.1}; Flags: Fragment;+++[H3BPM3_HUMAN|Unreviewed]SubName: Full=RNA polymerase II-associated protein 1 {ECO:0000313|Ensembl:ENSP00000455381}; Flags: Fragment;+++[H3BPY8_HUMAN|Unreviewed]SubName: Full=RNA polymerase II-associated protein 1 {ECO:0000313|Ensembl:ENSP00000455527}; Flags: Fragment;+++[H3BRE8_HUMAN|Unreviewed]SubName: Full=RNA polymerase II-associated protein 1 {ECO:0000313|Ensembl:ENSP00000456207};+++[H3BTJ6_HUMAN|Unreviewed]SubName: Full=RNA polymerase II-associated protein 1 {ECO:0000313|Ensembl:ENSP00000457203}; Flags: Fragment;"]
[26035,"'GLCE'",193,103,157,151,"01100///Metabolic pathways+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",null,"M00059///Glycosaminoglycan biosynthesis, heparan sulfate backbone",null,"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane","GO:0047464///heparosan-N-sulfate-glucuronate 5-epimerase activity+++GO:0016853///isomerase activity+++GO:0016857///racemase and epimerase activity, acting on carbohydrates and derivatives","GO:0030210///heparin biosynthetic process+++GO:0015012///heparan sulfate proteoglycan biosynthetic process","glucuronic acid epimerase","[GLCE_HUMAN|Reviewed]RecName: Full=D-glucuronyl C5-epimerase; EC=5.1.3.17 {ECO:0000269|PubMed:20118238, ECO:0000269|PubMed:22528493}; AltName: Full=Heparan sulfate C5-epimerase; Short=Hsepi; AltName: Full=Heparin/heparan sulfate:glucuronic acid C5-epimerase; AltName: Full=Heparosan-N-sulfate-glucuronate 5-epimerase;+++[H0YNP1_HUMAN|Unreviewed]SubName: Full=D-glucuronyl C5-epimerase {ECO:0000313|Ensembl:ENSP00000454092};"]
[26052,"'DNM3'",78,72,62,70.6666666666667,"05100///Bacterial invasion of epithelial cells+++04072///Phospholipase D signaling pathway+++04144///Endocytosis+++04721///Synaptic vesicle cycle+++04961///Endocrine and other factor-regulated calcium reabsorption","H00606///Early infantile epileptic encephalopathy+++H00264///Charcot-Marie-Tooth disease (CMT)+++H00700///Centronuclear myopathy+++H00865///Lethal congenital contractural syndrome (LCCS)",null,null,"GO:0061828///apical tubulobulbar complex+++GO:0005856///cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0098978///glutamatergic synapse+++GO:0045202///synapse+++GO:0061829///basal tubulobulbar complex+++GO:0005886///plasma membrane+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:0005737///cytoplasm+++GO:0044327///dendritic spine head+++GO:0043083///synaptic cleft+++GO:0045211///postsynaptic membrane+++GO:0098793///presynapse+++GO:0070062///extracellular exosome+++GO:0014069///postsynaptic density+++GO:0031410///cytoplasmic vesicle+++GO:0098844///postsynaptic endocytic zone membrane+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0001917///photoreceptor inner segment","GO:0016787///hydrolase activity+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0000166///nucleotide binding+++GO:0031802///type 5 metabotropic glutamate receptor binding+++GO:0031798///type 1 metabotropic glutamate receptor binding+++GO:0099186///structural constituent of postsynapse+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0050998///nitric-oxide synthase binding+++GO:0005515///protein binding","GO:0061001///regulation of dendritic spine morphogenesis+++GO:0051491///positive regulation of filopodium assembly+++GO:0007416///synapse assembly+++GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0048488///synaptic vesicle endocytosis+++GO:0046847///filopodium assembly+++GO:0006897///endocytosis+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:0099173///postsynapse organization+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:1903423///positive regulation of synaptic vesicle recycling+++GO:0031623///receptor internalization+++GO:0050803///regulation of synapse structure or activity","dynamin 3","[DYN3_HUMAN|Reviewed]RecName: Full=Dynamin-3; EC=3.6.5.5; AltName: Full=Dynamin, testicular; AltName: Full=T-dynamin;+++[E5RHK8_HUMAN|Unreviewed]SubName: Full=Dynamin-3 {ECO:0000313|Ensembl:ENSP00000429701};+++[E5RIK2_HUMAN|Unreviewed]SubName: Full=Dynamin-3 {ECO:0000313|Ensembl:ENSP00000429416}; Flags: Fragment;+++[H0YBC6_HUMAN|Unreviewed]SubName: Full=Dynamin-3 {ECO:0000313|Ensembl:ENSP00000429165}; Flags: Fragment;"]
[26084,"'ARHGEF26'",115,89,109,104.333333333333,"05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0005829///cytosol+++GO:0001726///ruffle+++GO:0042995///cell projection","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0097178///ruffle assembly+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0001886///endothelial cell morphogenesis","Rho guanine nucleotide exchange factor 26","[ARHGQ_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 26; AltName: Full=SH3 domain-containing guanine exchange factor;+++[A0A140VJU4_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 171 {ECO:0000313|EMBL:AEE61081.1};+++[A0A2X0U4M4_HUMAN|Unreviewed]SubName: Full=ARHGEF26 {ECO:0000313|EMBL:SPT35730.1}; Flags: Fragment;+++[B3KXG0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45349 fis, clone BRHIP3011460, highly similar to Homo sapiens Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF), mRNA {ECO:0000313|EMBL:BAG54472.1};"]
[26119,"'LDLRAP1'",920,978,840,912.666666666667,"04144///Endocytosis+++04979///Cholesterol metabolism","H01918///Familial autosomal recessive hypercholesterolemia",null,null,"GO:0009925///basal plasma membrane+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005883///neurofilament+++GO:0005737///cytoplasm+++GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0055037///recycling endosome+++GO:0030665///clathrin-coated vesicle membrane","GO:0035615///clathrin adaptor activity+++GO:0035591///signaling adaptor activity+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0035650///AP-1 adaptor complex binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0001540///amyloid-beta binding+++GO:0030276///clathrin binding+++GO:0005515///protein binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0001784///phosphotyrosine residue binding+++GO:0050750///low-density lipoprotein particle receptor binding","GO:0031623///receptor internalization+++GO:0006629///lipid metabolic process+++GO:0090118///receptor-mediated endocytosis involved in cholesterol transport+++GO:0071345///cellular response to cytokine stimulus+++GO:0009967///positive regulation of signal transduction+++GO:0042632///cholesterol homeostasis+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0034383///low-density lipoprotein particle clearance+++GO:0008202///steroid metabolic process+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0043393///regulation of protein binding+++GO:1905602///positive regulation of receptor-mediated endocytosis involved in cholesterol transport+++GO:0008203///cholesterol metabolic process+++GO:1905581///positive regulation of low-density lipoprotein particle clearance+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0042982///amyloid precursor protein metabolic process+++GO:0061024///membrane organization+++GO:0030301///cholesterol transport+++GO:0090205///positive regulation of cholesterol metabolic process","low density lipoprotein receptor adaptor protein 1","[ARH_HUMAN|Reviewed]RecName: Full=Low density lipoprotein receptor adapter protein 1 {ECO:0000305}; AltName: Full=Autosomal recessive hypercholesterolemia protein {ECO:0000303|PubMed:11326085};+++[B3KR97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33900 fis, clone CTONG2008262, highly similar to Low density lipoprotein receptor adapter protein 1 {ECO:0000313|EMBL:BAG52309.1};"]
[26147,"'PHF19'",99,89,77,88.3333333333333,"05169///Epstein-Barr virus infection+++04210///Apoptosis+++04064///NF-kappa B signaling pathway+++05222///Small cell lung cancer+++05203///Viral carcinogenesis+++05200///Pathways in cancer+++04668///TNF signaling pathway+++05168///Herpes simplex infection+++05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0035098///ESC/E(Z) complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding+++GO:0043565///sequence-specific DNA binding","GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0019827///stem cell population maintenance+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0048863///stem cell differentiation+++GO:0061087///positive regulation of histone H3-K27 methylation","PHD finger protein 19","[PHF19_HUMAN|Reviewed]RecName: Full=PHD finger protein 19; AltName: Full=Polycomb-like protein 3; Short=hPCL3;+++[A0A087X169_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000483946};+++[B0QZ50_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000395938}; Flags: Fragment;+++[B0QZ51_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000404655}; Flags: Fragment;+++[B0QZ72_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000408479}; Flags: Fragment;+++[B7Z887_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55009, highly similar to Homo sapiens PHD finger protein 19 (PHF19), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH13873.1};+++[B7Z8H3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53261, highly similar to Homo sapiens PHD finger protein 19 (PHF19), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH13959.1};+++[F5H8K3_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000407433};+++[X6RER8_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000397935}; Flags: Fragment;"]
[261734,"'NPHP4'",177,145,141,154.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00538///Senior-Loken syndrome+++H00537///Nephronophthisis",null,null,"GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0036064///ciliary basal body+++GO:0097546///ciliary base+++GO:0005923///bicellular tight junction+++GO:0005815///microtubule organizing center+++GO:0042995///cell projection+++GO:0005813///centrosome+++GO:0005929///cilium+++GO:0097470///ribbon synapse+++GO:0005829///cytosol+++GO:0035869///ciliary transition zone+++GO:0032391///photoreceptor connecting cilium+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005911///cell-cell junction+++GO:0097730///non-motile cilium","GO:0005198///structural molecule activity+++GO:0005515///protein binding","GO:0030036///actin cytoskeleton organization+++GO:0098609///cell-cell adhesion+++GO:0060041///retina development in camera-type eye+++GO:0035845///photoreceptor cell outer segment organization+++GO:0007165///signal transduction+++GO:1903348///positive regulation of bicellular tight junction assembly+++GO:0035329///hippo signaling+++GO:0045494///photoreceptor cell maintenance+++GO:0007632///visual behavior+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0030317///flagellated sperm motility+++GO:0097711///ciliary basal body-plasma membrane docking","nephrocystin 4","[NPHP4_HUMAN|Reviewed]RecName: Full=Nephrocystin-4; AltName: Full=Nephroretinin;+++[B3KW36_HUMAN|Unreviewed]SubName: Full=cDNA FLJ42080 fis, clone SYNOV4000249, highly similar to Nephrocystin-4 {ECO:0000313|EMBL:BAG53998.1};+++[D6RA06_HUMAN|Unreviewed]SubName: Full=Nephrocystin-4 {ECO:0000313|Ensembl:ENSP00000367411};+++[H0YA08_HUMAN|Unreviewed]SubName: Full=Nephrocystin-4 {ECO:0000313|Ensembl:ENSP00000425745}; Flags: Fragment;"]
[26211,"'OR2F1'",0,1,1,0.666666666666667,"04740///Olfactory transduction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004984///olfactory receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0050896///response to stimulus+++GO:0007608///sensory perception of smell+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","olfactory receptor family 2 subfamily F member 1 (gene/pseudogene)","[OR2F1_HUMAN|Reviewed]RecName: Full=Olfactory receptor 2F1; AltName: Full=Olfactory receptor 2F3; AltName: Full=Olfactory receptor 2F4; AltName: Full=Olfactory receptor 2F5; AltName: Full=Olfactory receptor-like protein OLF3;+++[A0A126GV98_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GWI1_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GWI5_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GWK3_HUMAN|Unreviewed]SubName: Full=OR2F1 {ECO:0000313|EMBL:ALI87788.1};+++[A0A126GWK4_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[L8E9J5_HUMAN|Unreviewed]SubName: Full=Alternative protein OR2F1 {ECO:0000313|EMBL:CCQ43411.1};+++[O43886_HUMAN|Unreviewed]SubName: Full=Olfactory receptor {ECO:0000313|EMBL:AAC39631.1}; Flags: Fragment;+++[O43887_HUMAN|Unreviewed]SubName: Full=Olfactory receptor {ECO:0000313|EMBL:AAC39632.1}; Flags: Fragment;"]
[2625,"'GATA3'",30,20,22,24,"04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04928///Parathyroid hormone synthesis, secretion and action","H01360///Allergic rhinitis+++H01271///Hypoparathyroidism with sensorineural deafness and renal dysplasia",null,null,"GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005134///interleukin-2 receptor binding+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0003712///transcription coregulator activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0071837///HMG box domain binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0070888///E-box binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding","GO:0072107///positive regulation of ureteric bud formation+++GO:0045786///negative regulation of cell cycle+++GO:0042472///inner ear morphogenesis+++GO:0072179///nephric duct formation+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:0048485///sympathetic nervous system development+++GO:0009791///post-embryonic development+++GO:0045061///thymic T cell selection+++GO:0007596///blood coagulation+++GO:0009653///anatomical structure morphogenesis+++GO:0050728///negative regulation of inflammatory response+++GO:0060676///ureteric bud formation+++GO:0001806///type IV hypersensitivity+++GO:0035457///cellular response to interferon-alpha+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045064///T-helper 2 cell differentiation+++GO:0007399///nervous system development+++GO:0001764///neuron migration+++GO:2000683///regulation of cellular response to X-ray+++GO:0061085///regulation of histone H3-K27 methylation+++GO:0060374///mast cell differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060037///pharyngeal system development+++GO:0045087///innate immune response+++GO:0001775///cell activation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0071599///otic vesicle development+++GO:0001701///in utero embryonic development+++GO:0035898///parathyroid hormone secretion+++GO:2000667///positive regulation of interleukin-13 secretion+++GO:2000611///positive regulation of thyroid hormone generation+++GO:2000703///negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation+++GO:0009615///response to virus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001709///cell fate determination+++GO:0032703///negative regulation of interleukin-2 production+++GO:0008584///male gonad development+++GO:0043627///response to estrogen+++GO:0061290///canonical Wnt signaling pathway involved in metanephric kidney development+++GO:0072602///interleukin-4 secretion+++GO:0071773///cellular response to BMP stimulus+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0030217///T cell differentiation+++GO:0060065///uterus development+++GO:0035799///ureter maturation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0043583///ear development+++GO:0050852///T cell receptor signaling pathway+++GO:0032736///positive regulation of interleukin-13 production+++GO:0031929///TOR signaling+++GO:2000734///negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation+++GO:0071345///cellular response to cytokine stimulus+++GO:0000902///cell morphogenesis+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0009967///positive regulation of signal transduction+++GO:0006366///transcription by RNA polymerase II+++GO:0032753///positive regulation of interleukin-4 production+++GO:2000146///negative regulation of cell motility+++GO:0019221///cytokine-mediated signaling pathway+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0048538///thymus development+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0043370///regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0003180///aortic valve morphogenesis+++GO:0060231///mesenchymal to epithelial transition+++GO:0010629///negative regulation of gene expression+++GO:2000114///regulation of establishment of cell polarity+++GO:0090102///cochlea development+++GO:2000607///negative regulation of cell proliferation involved in mesonephros development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0035162///embryonic hemopoiesis+++GO:0030218///erythrocyte differentiation+++GO:0072001///renal system development+++GO:0045582///positive regulation of T cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048568///embryonic organ development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0072182///regulation of nephron tubule epithelial cell differentiation+++GO:0072676///lymphocyte migration+++GO:0048469///cell maturation+++GO:0048589///developmental growth+++GO:0001822///kidney development+++GO:0072178///nephric duct morphogenesis+++GO:0060017///parathyroid gland development+++GO:0042421///norepinephrine biosynthetic process+++GO:0010628///positive regulation of gene expression+++GO:0002088///lens development in camera-type eye+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0008285///negative regulation of cell proliferation+++GO:0010332///response to gamma radiation+++GO:0030182///neuron differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0006338///chromatin remodeling+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0002376///immune system process+++GO:0007411///axon guidance+++GO:0045597///positive regulation of cell differentiation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0006952///defense response+++GO:0007165///signal transduction+++GO:0043523///regulation of neuron apoptotic process+++GO:0010975///regulation of neuron projection development+++GO:0032754///positive regulation of interleukin-5 production+++GO:0045471///response to ethanol+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0048872///homeostasis of number of cells+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032689///negative regulation of interferon-gamma production+++GO:0071442///positive regulation of histone H3-K14 acetylation+++GO:0006959///humoral immune response+++GO:0001823///mesonephros development+++GO:0002572///pro-T cell differentiation+++GO:0071353///cellular response to interleukin-4+++GO:2000664///positive regulation of interleukin-5 secretion+++GO:0016579///protein deubiquitination+++GO:0072643///interferon-gamma secretion+++GO:0003281///ventricular septum development+++GO:0042493///response to drug+++GO:1901536///negative regulation of DNA demethylation+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:0001819///positive regulation of cytokine production","GATA binding protein 3","[GATA3_HUMAN|Reviewed]RecName: Full=Trans-acting T-cell-specific transcription factor GATA-3; AltName: Full=GATA-binding factor 3;+++[A0A2R8Y2A9_HUMAN|Unreviewed]SubName: Full=Trans-acting T-cell-specific transcription factor GATA-3 {ECO:0000313|Ensembl:ENSP00000493486}; Flags: Fragment;+++[A0A2R8Y4T2_HUMAN|Unreviewed]SubName: Full=Trans-acting T-cell-specific transcription factor GATA-3 {ECO:0000313|Ensembl:ENSP00000494284}; Flags: Fragment;"]
[26276,"'VPS33B'",166,174,182,174,{"$nulls":4},"GO:0005768///endosome+++GO:0030123///AP-3 adaptor complex+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0031091///platelet alpha granule+++GO:0030897///HOPS complex+++GO:0005764///lysosome+++GO:0071439///clathrin complex+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0031902///late endosome membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome+++GO:0005769///early endosome+++GO:0005770///late endosome+++GO:0031901///early endosome membrane","GO:0005515///protein binding","GO:0061025///membrane fusion+++GO:0006904///vesicle docking involved in exocytosis+++GO:0016192///vesicle-mediated transport+++GO:0070889///platelet alpha granule organization+++GO:0007032///endosome organization+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0008333///endosome to lysosome transport+++GO:0015031///protein transport+++GO:0032418///lysosome localization+++GO:0032963///collagen metabolic process+++GO:0032400///melanosome localization+++GO:0097352///autophagosome maturation","VPS33B, late endosome and lysosome associated","[VP33B_HUMAN|Reviewed]RecName: Full=Vacuolar protein sorting-associated protein 33B; Short=hVPS33B;+++[A0A0S2Z555_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting 33-like protein B isoform 3 {ECO:0000313|EMBL:ALQ34050.1};+++[A0A0S2Z577_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting 33-like protein B isoform 1 {ECO:0000313|EMBL:ALQ34048.1}; SubName: Full=Vacuolar protein sorting 33B (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAX02139.1}; Flags: Fragment;+++[A0A0S2Z589_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting 33-like protein B isoform 2 {ECO:0000313|EMBL:ALQ34049.1};+++[B7Z1N4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55636, highly similar to Vacuolar protein sorting 33B {ECO:0000313|EMBL:BAH11570.1};+++[F5H008_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 33B {ECO:0000313|Ensembl:ENSP00000444053};+++[G3V3F9_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 33B {ECO:0000313|Ensembl:ENSP00000460413};"]
[2629,"'GBA'",7454,7418,7280,7384,"00600///Sphingolipid metabolism+++04142///Lysosome+++01100///Metabolic pathways+++00511///Other glycan degradation","H00426///Defects in the degradation of ganglioside+++H00126///Gaucher disease+++H00066///Lewy body dementia (LBD)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,"R01498///D-Glucosyl-N-acylsphingosine glucohydrolase   beta-D-Glucosyl-(1<->1)-ceramide + H2O <=> D-Glucose + N-Acylsphingosine","GO:0005764///lysosome+++GO:0043202///lysosomal lumen+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane+++GO:0005765///lysosomal membrane+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome","GO:0005102///signaling receptor binding+++GO:0005124///scavenger receptor binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004348///glucosylceramidase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds","GO:0032269///negative regulation of cellular protein metabolic process+++GO:1903061///positive regulation of protein lipidation+++GO:0009268///response to pH+++GO:1904457///positive regulation of neuronal action potential+++GO:0007005///mitochondrion organization+++GO:0051246///regulation of protein metabolic process+++GO:1905165///regulation of lysosomal protein catabolic process+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043627///response to estrogen+++GO:0006629///lipid metabolic process+++GO:0033574///response to testosterone+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043243///positive regulation of protein complex disassembly+++GO:0050728///negative regulation of inflammatory response+++GO:1905037///autophagosome organization+++GO:0033561///regulation of water loss via skin+++GO:0043407///negative regulation of MAP kinase activity+++GO:0051247///positive regulation of protein metabolic process+++GO:0032268///regulation of cellular protein metabolic process+++GO:1901805///beta-glucoside catabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006680///glucosylceramide catabolic process+++GO:0032715///negative regulation of interleukin-6 production+++GO:0008152///metabolic process+++GO:0031175///neuron projection development+++GO:0043589///skin morphogenesis+++GO:0036473///cell death in response to oxidative stress+++GO:0023021///termination of signal transduction+++GO:0009267///cellular response to starvation+++GO:0032463///negative regulation of protein homooligomerization+++GO:0071548///response to dexamethasone+++GO:0097066///response to thyroid hormone+++GO:0071356///cellular response to tumor necrosis factor+++GO:1901215///negative regulation of neuron death+++GO:0046513///ceramide biosynthetic process+++GO:0016241///regulation of macroautophagy+++GO:0046512///sphingosine biosynthetic process+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization","glucosylceramidase beta","[GLCM_HUMAN|Reviewed]RecName: Full=Glucosylceramidase; EC=3.2.1.45; AltName: Full=Acid beta-glucosidase; AltName: Full=Alglucerase; AltName: Full=Beta-glucocerebrosidase; Short=Beta-GC; AltName: Full=D-glucosyl-N-acylsphingosine glucohydrolase; AltName: Full=Imiglucerase; Flags: Precursor;+++[A0A068F658_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[A0A0G2JLB3_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[A0A0G2JNZ0_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[A0A0G2JNZ5_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[B7Z6S9_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};+++[D3DV87_HUMAN|Unreviewed]RecName: Full=Glucosylceramidase {ECO:0000256|RuleBase:RU361188}; EC=3.2.1.45 {ECO:0000256|RuleBase:RU361188};"]
[26471,"'NUPR1'",2718,3382,2103,2734.33333333333,"05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0032993///protein-DNA complex","GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006473///protein acetylation+++GO:0031401///positive regulation of protein modification process+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0002526///acute inflammatory response+++GO:0008584///male gonad development+++GO:0043065///positive regulation of apoptotic process+++GO:0009636///response to toxic substance+++GO:0035914///skeletal muscle cell differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:2000194///regulation of female gonad development+++GO:0065003///protein-containing complex assembly","nuclear protein 1, transcriptional regulator","[NUPR1_HUMAN|Reviewed]RecName: Full=Nuclear protein 1 {ECO:0000305}; AltName: Full=Candidate of metastasis 1; AltName: Full=Nuclear transcriptional regulator protein 1 {ECO:0000312|HGNC:HGNC:29990}; AltName: Full=Protein p8;+++[A0A024QZC4_HUMAN|Unreviewed]SubName: Full=p8 protein (Candidate of metastasis 1), isoform CRA_a {ECO:0000313|EMBL:EAW52276.1};+++[H3BS92_HUMAN|Unreviewed]SubName: Full=Nuclear protein 1 {ECO:0000313|Ensembl:ENSP00000456597};"]
[26505,"'CNNM3'",479,458.93,469.7,469.21,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00577///Symptomatic generalized epilepsies+++H01015///Jalili syndrome",null,null,"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0006811///ion transport","cyclin and CBS domain divalent metal cation transport mediator 3","[CNNM3_HUMAN|Reviewed]RecName: Full=Metal transporter CNNM3; AltName: Full=Ancient conserved domain-containing protein 3; AltName: Full=Cyclin-M3;"]
[26517,"'TIMM13'",704,725,594,674.333333333333,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0001650///fibrillar center+++GO:0042719///mitochondrial intermembrane space protein transporter complex+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane","GO:0008565///protein transporter activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0015031///protein transport+++GO:0007605///sensory perception of sound+++GO:0045039///protein import into mitochondrial inner membrane+++GO:0006626///protein targeting to mitochondrion+++GO:0072321///chaperone-mediated protein transport","translocase of inner mitochondrial membrane 13","[TIM13_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim13;+++[K7EIT2_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim13 {ECO:0000313|Ensembl:ENSP00000464881}; SubName: Full=Translocase of inner mitochondrial membrane 13 homolog (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW69381.1};"]
[26610,"'ELP4'",335,341.02,290,322.006666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00635///Aniridia+++H01827///Epileptic encephalopathy with continuous spike-waves during slow-wave sleep+++H01514///Landau-Kleffner syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0033588///Elongator holoenzyme complex+++GO:0008023///transcription elongation factor complex","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0008607///phosphorylase kinase regulator activity+++GO:0046872///metal ion binding","GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0002098///tRNA wobble uridine modification+++GO:0006310///DNA recombination+++GO:0006368///transcription elongation from RNA polymerase II promoter","elongator acetyltransferase complex subunit 4","[ELP4_HUMAN|Reviewed]RecName: Full=Elongator complex protein 4; Short=hELP4; AltName: Full=PAX6 neighbor gene protein;+++[G5E9D4_HUMAN|Unreviewed]SubName: Full=Elongation protein 4 homolog (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW68238.1}; SubName: Full=Elongator complex protein 4 {ECO:0000313|Ensembl:ENSP00000379267};+++[Q9H4R8_HUMAN|Unreviewed]SubName: Full=DJ68P15A.1 (Novel protein) {ECO:0000313|EMBL:CAC10331.1}; Flags: Fragment;"]
[266743,"'NPAS4'",16,24,15,18.3333333333333,{"$nulls":4},"GO:0098794///postsynapse+++GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0001012///RNA polymerase II regulatory region DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035176///social behavior+++GO:0048167///regulation of synaptic plasticity+++GO:0007616///long-term memory+++GO:0007612///learning+++GO:0007399///nervous system development+++GO:0071386///cellular response to corticosterone stimulus+++GO:0060079///excitatory postsynaptic potential+++GO:0030154///cell differentiation+++GO:0007614///short-term memory+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060080///inhibitory postsynaptic potential+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1904862///inhibitory synapse assembly","neuronal PAS domain protein 4","[NPAS4_HUMAN|Reviewed]RecName: Full=Neuronal PAS domain-containing protein 4 {ECO:0000305}; Short=Neuronal PAS4 {ECO:0000305}; AltName: Full=Class E basic helix-loop-helix protein 79 {ECO:0000305}; Short=bHLHe79 {ECO:0000305}; AltName: Full=HLH-PAS transcription factor NXF {ECO:0000303|PubMed:14701734}; AltName: Full=PAS domain-containing protein 10 {ECO:0000305};"]
[2683,"'B4GALT1'",5861,5475,5754,5696.66666666667,"00052///Galactose metabolism+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00514///Other types of O-glycan biosynthesis+++00510///N-Glycan biosynthesis+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++00513///Various types of N-glycan biosynthesis+++01100///Metabolic pathways+++00515///Mannose type O-glycan biosynthesis","H00119///Congenital disorders of glycosylation (CDG) type II","M00075///N-glycan biosynthesis, complex type+++M00071///Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer","R00503///UDP-alpha-D-galactose:D-glucose 4-beta-D-galactosyltransferase   UDP-alpha-D-galactose + D-Glucose <=> UDP + Lactose+++R06033///UDP-D-galactose + nLc5Cer <=> UDP + nLc6Cer+++R05977///UDP-D-galactose + Lc3Cer <=> UDP + Paragloboside+++R09299///UDP-D-galactose + G13053 <=> UDP + G13054+++R05989///UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase   2 UDP-D-galactose + G00016 <=> 2 UDP + G00017+++R07617///UDP-D-galactose + G00025 <=> UDP + G11136","GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0000138///Golgi trans cisterna+++GO:0005576///extracellular region+++GO:0016323///basolateral plasma membrane+++GO:0035577///azurophil granule membrane+++GO:0030667///secretory granule membrane+++GO:0016021///integral component of membrane+++GO:0030057///desmosome+++GO:0009897///external side of plasma membrane+++GO:0005615///extracellular space+++GO:0030175///filopodium+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0032580///Golgi cisterna membrane+++GO:0000139///Golgi membrane+++GO:0009986///cell surface+++GO:0031526///brush border membrane","GO:0035250///UDP-galactosyltransferase activity+++GO:0043014///alpha-tubulin binding+++GO:0030145///manganese ion binding+++GO:0048487///beta-tubulin binding+++GO:0016740///transferase activity+++GO:0004461///lactose synthase activity+++GO:0008378///galactosyltransferase activity+++GO:0003831///beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity+++GO:0003945///N-acetyllactosamine synthase activity+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042803///protein homodimerization activity","GO:0005989///lactose biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0045136///development of secondary sexual characteristics+++GO:0043312///neutrophil degranulation+++GO:0009312///oligosaccharide biosynthetic process+++GO:0006012///galactose metabolic process+++GO:0042060///wound healing+++GO:0007341///penetration of zona pellucida+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0060046///regulation of acrosome reaction+++GO:0007155///cell adhesion+++GO:0060055///angiogenesis involved in wound healing+++GO:0043065///positive regulation of apoptotic process+++GO:0009101///glycoprotein biosynthetic process+++GO:0050900///leukocyte migration+++GO:0002526///acute inflammatory response+++GO:0018146///keratan sulfate biosynthetic process+++GO:0051260///protein homooligomerization+++GO:0002064///epithelial cell development+++GO:0007339///binding of sperm to zona pellucida+++GO:0005975///carbohydrate metabolic process+++GO:0030198///extracellular matrix organization","beta-1,4-galactosyltransferase 1","[B4GT1_HUMAN|Reviewed]RecName: Full=Beta-1,4-galactosyltransferase 1; Short=Beta-1,4-GalTase 1; Short=Beta4Gal-T1; Short=b4Gal-T1; EC=2.4.1.-; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1; Includes: RecName: Full=Lactose synthase A protein; EC=2.4.1.22; Includes: RecName: Full=N-acetyllactosamine synthase; EC=2.4.1.90; AltName: Full=Nal synthase; Includes: RecName: Full=Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; EC=2.4.1.38; Includes: RecName: Full=Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; EC=2.4.1.-; Contains: RecName: Full=Processed beta-1,4-galactosyltransferase 1;+++[Q86XA6_HUMAN|Unreviewed]SubName: Full=B4GALT1 protein {ECO:0000313|EMBL:AAH45773.1}; SubName: Full=Beta-1,4-galactosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440341};+++[W6MEN3_HUMAN|Unreviewed]SubName: Full=Beta-1,4-galactosyltransferase 1 {ECO:0000313|EMBL:CDJ98631.1};+++[W6MEN4_HUMAN|Unreviewed]SubName: Full=Beta-1,4-galactosyltransferase 1 {ECO:0000313|EMBL:CDJ98633.1};"]
[26958,"'COPG2'",325,290,268,294.333333333333,{"$nulls":4},"GO:0030133///transport vesicle+++GO:0030117///membrane coat+++GO:0030126///COPI vesicle coat+++GO:0005783///endoplasmic reticulum+++GO:0031410///cytoplasmic vesicle+++GO:0005789///endoplasmic reticulum membrane+++GO:0030663///COPI-coated vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus","GO:0005198///structural molecule activity","GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0072384///organelle transport along microtubule+++GO:0009306///protein secretion+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport","coatomer protein complex subunit gamma 2","[COPG2_HUMAN|Reviewed]RecName: Full=Coatomer subunit gamma-2; AltName: Full=Gamma-2-coat protein; Short=Gamma-2-COP;+++[A0A140VK12_HUMAN|Unreviewed]RecName: Full=Coatomer subunit gamma {ECO:0000256|PIRNR:PIRNR037093};+++[Q96PK0_HUMAN|Unreviewed]SubName: Full=COPG2 {ECO:0000313|EMBL:AAL17778.1}; Flags: Fragment;+++[Q9NSM7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp761N09121 {ECO:0000313|EMBL:CAB82364.1}; Flags: Fragment;"]
[2701,"'GJA4'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005922///connexin complex","GO:0005515///protein binding","GO:0007267///cell-cell signaling+++GO:0001568///blood vessel development+++GO:0048265///response to pain+++GO:0007043///cell-cell junction assembly+++GO:0007154///cell communication+++GO:0006816///calcium ion transport+++GO:0003158///endothelium development","gap junction protein alpha 4","[CXA4_HUMAN|Reviewed]RecName: Full=Gap junction alpha-4 protein; AltName: Full=Connexin-37; Short=Cx37;+++[Q5JW71_HUMAN|Unreviewed]RecName: Full=Gap junction protein {ECO:0000256|RuleBase:RU000630}; Flags: Fragment;"]
[27034,"'ACAD8'",247,233,263,247.666666666667,"00280///Valine, leucine and isoleucine degradation+++01100///Metabolic pathways","H01279///Isobutyryl-CoA dehydrogenase (IBD) deficiency",null,"R02661///2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase   2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0050660///flavin adenine dinucleotide binding+++GO:0016491///oxidoreductase activity+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors","GO:0006629///lipid metabolic process+++GO:0009083///branched-chain amino acid catabolic process+++GO:0006574///valine catabolic process+++GO:0055114///oxidation-reduction process","acyl-CoA dehydrogenase family member 8","[ACAD8_HUMAN|Reviewed]RecName: Full=Isobutyryl-CoA dehydrogenase, mitochondrial; EC=1.3.99.-; AltName: Full=Activator-recruited cofactor 42 kDa component; Short=ARC42; AltName: Full=Acyl-CoA dehydrogenase family member 8; Short=ACAD-8; Flags: Precursor;+++[E9PKP9_HUMAN|Unreviewed]SubName: Full=Isobutyryl-CoA dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000431532};+++[E9PLS3_HUMAN|Unreviewed]SubName: Full=Isobutyryl-CoA dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000431310};+++[Q6ZUS0_HUMAN|Unreviewed]SubName: Full=Acyl-Coenzyme A dehydrogenase family, member 8, isoform CRA_b {ECO:0000313|EMBL:EAW67834.1}; SubName: Full=cDNA FLJ43383 fis, clone OCBBF2006058, highly similar to Homo sapiens acyl-Coenzyme A dehydrogenase-8 mRNA {ECO:0000313|EMBL:BAC86149.1};"]
[27077,"'B9D1'",278,291,335,301.333333333333,"04657///IL-17 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04722///Neurotrophin signaling pathway+++04921///Oxytocin signaling pathway+++04010///MAPK signaling pathway+++04011///MAPK signaling pathway - yeast+++04540///Gap junction+++04144///Endocytosis+++04139///Mitophagy - yeast+++04138///Autophagy - yeast+++05206///MicroRNAs in cancer+++04912///GnRH signaling pathway","H00530///Joubert syndrome+++H00261///Meckel syndrome (MKS)","M00690///MAPK (ERK5) signaling",null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0036038///MKS complex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0036064///ciliary basal body+++GO:0035869///ciliary transition zone+++GO:0042995///cell projection","GO:0008158///hedgehog receptor activity","GO:0001701///in utero embryonic development+++GO:0030030///cell projection organization+++GO:0032880///regulation of protein localization+++GO:0060563///neuroepithelial cell differentiation+++GO:0007224///smoothened signaling pathway+++GO:0001944///vasculature development+++GO:0060271///cilium assembly+++GO:0042733///embryonic digit morphogenesis+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0043010///camera-type eye development","B9 domain containing 1","[B9D1_HUMAN|Reviewed]RecName: Full=B9 domain-containing protein 1; AltName: Full=MKS1-related protein 1;+++[A0A0B4J223_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000433359};+++[A0A2R8Y5M4_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000494660};+++[A0A2R8Y646_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000495045};+++[A0A2R8Y822_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496409};+++[A0A2R8YD57_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000493599}; Flags: Fragment;+++[A0A2R8YFJ1_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496502};+++[A8MTX4_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000378977};+++[A8MYG7_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000378978};+++[B4DEW0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60445, highly similar to Homo sapiens B9 protein (EPPB9), mRNA {ECO:0000313|EMBL:BAG57221.1};+++[B4DN64_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57537 {ECO:0000313|EMBL:BAG60126.1};+++[H7C3B7_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410835}; Flags: Fragment;+++[I3L126_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000458525}; Flags: Fragment;+++[I3L2R1_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459857};+++[I3L435_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000460939};+++[J3KSN2_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000462565}; Flags: Fragment;+++[J3QKN6_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000463165}; Flags: Fragment;+++[J3QKV6_HUMAN|Unreviewed]SubName: Full=B9 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000463255}; Flags: Fragment;"]
[2710,"'GK'",12,8,14,11.3333333333333,"01100///Metabolic pathways+++04626///Plant-pathogen interaction+++03320///PPAR signaling pathway+++00561///Glycerolipid metabolism","H00552///Chromosome Xp21 deletion syndrome+++H02013///Glycerol kinase deficiency",null,"R00847///ATP:glycerol 3-phosphotransferase   ATP + Glycerol <=> ADP + sn-Glycerol 3-phosphate","GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion","GO:0046872///metal ion binding+++GO:0004370///glycerol kinase activity+++GO:0005524///ATP binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006071///glycerol metabolic process+++GO:0046167///glycerol-3-phosphate biosynthetic process+++GO:0006351///transcription, DNA-templated+++GO:0019563///glycerol catabolic process+++GO:0006641///triglyceride metabolic process+++GO:0019432///triglyceride biosynthetic process","glycerol kinase","[GLPK_HUMAN|Reviewed]RecName: Full=Glycerol kinase; Short=GK; Short=Glycerokinase; EC=2.7.1.30; AltName: Full=ATP:glycerol 3-phosphotransferase;+++[A0A024RBY6_HUMAN|Unreviewed]SubName: Full=Glycerol kinase, isoform CRA_c {ECO:0000313|EMBL:EAW99056.1};+++[A6NP46_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000368224};+++[B4DH54_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61248, highly similar to Glycerol kinase, testis specific 1 {ECO:0000313|EMBL:BAG58015.1};+++[F8WBI8_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000417942};+++[F8WC39_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000418873};+++[F8WDA9_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000420676};+++[F8WF44_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000419332};+++[H7BYD2_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000368221}; Flags: Fragment;+++[H7C2A0_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000404682}; Flags: Fragment;+++[H7C5F6_HUMAN|Unreviewed]SubName: Full=Glycerol kinase {ECO:0000313|Ensembl:ENSP00000419771}; Flags: Fragment;"]
[27132,"'CPNE7'",70,79,69,72.6666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0005544///calcium-dependent phospholipid binding+++GO:0005215///transporter activity+++GO:0005515///protein binding","GO:0071277///cellular response to calcium ion+++GO:0006629///lipid metabolic process+++GO:0046474///glycerophospholipid biosynthetic process","copine 7","[CPNE7_HUMAN|Reviewed]RecName: Full=Copine-7 {ECO:0000305}; AltName: Full=Copine VII {ECO:0000303|PubMed:10534407, ECO:0000312|HGNC:HGNC:2320};+++[E9PJ31_HUMAN|Unreviewed]SubName: Full=Copine-7 {ECO:0000313|Ensembl:ENSP00000431863};+++[H0YE30_HUMAN|Unreviewed]SubName: Full=Copine-7 {ECO:0000313|Ensembl:ENSP00000434886}; Flags: Fragment;+++[H0YEH8_HUMAN|Unreviewed]SubName: Full=Copine-7 {ECO:0000313|Ensembl:ENSP00000435876}; Flags: Fragment;+++[H3BP03_HUMAN|Unreviewed]SubName: Full=Copine-7 {ECO:0000313|Ensembl:ENSP00000455086}; Flags: Fragment;"]
[27158,"'NDOR1'",624,570,698,630.666666666667,"04928///Parathyroid hormone synthesis, secretion and action","H01298///Pulmonary alveolar microlithiasis (PALM)+++H00888///Nephrolithiasis/osteoporosis, hypophosphatemic+++H00214///Hypophosphatemic rickets+++H01198///Fanconi renotubular syndrome (FTS)+++H02138///Hereditary hypophophatemic rickets with hypercalciuria",null,null,"GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0045111///intermediate filament cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0010181///FMN binding+++GO:0003958///NADPH-hemoprotein reductase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0050661///NADP binding+++GO:0005515///protein binding","GO:0055114///oxidation-reduction process+++GO:0008219///cell death+++GO:0016226///iron-sulfur cluster assembly+++GO:0036245///cellular response to menadione","NADPH dependent diflavin oxidoreductase 1","[NDOR1_HUMAN|Reviewed]RecName: Full=NADPH-dependent diflavin oxidoreductase 1 {ECO:0000255|HAMAP-Rule:MF_03178}; EC=1.18.1.- {ECO:0000255|HAMAP-Rule:MF_03178}; AltName: Full=NADPH-dependent FMN and FAD-containing oxidoreductase {ECO:0000255|HAMAP-Rule:MF_03178}; AltName: Full=Novel reductase 1;"]
[2720,"'GLB1'",7890,9053,8446,8463,"00531///Glycosaminoglycan degradation+++04142///Lysosome+++00604///Glycosphingolipid biosynthesis - ganglio series+++00511///Other glycan degradation+++00600///Sphingolipid metabolism+++01100///Metabolic pathways+++00052///Galactose metabolism","H00123///Mucopolysaccharidosis type IV (MPS4)+++H00421///Mucopolysaccharidosis (MPS)+++H00281///GM1 gangliosidosis+++H00276///Galactosialidosis+++H00422///Glycoproteinoses+++H00426///Defects in the degradation of ganglioside","M00079///Keratan sulfate degradation","R07807///G01977 + H2O <=> G13073 + D-Galactose+++R03355///beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase   beta-D-Galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> beta-D-Glucosyl-(1<->1)-ceramide + D-Galactose+++R01678///Lactose galactohydrolase   Lactose + H2O <=> alpha-D-Glucose + D-Galactose+++R06010///GM1 + H2O <=> GM2 + D-Galactose+++R04633///D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D- galactosyl-D-glucosylceramide galactohydrolase   D-Galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + H2O <=> N-Acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + D-Galactose","GO:0005764///lysosome+++GO:0005615///extracellular space+++GO:0005773///vacuole+++GO:1904813///ficolin-1-rich granule lumen+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0048471///perinuclear region of cytoplasm+++GO:0043202///lysosomal lumen+++GO:0070062///extracellular exosome+++GO:0035578///azurophil granule lumen+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0016936///galactoside binding+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016787///hydrolase activity+++GO:0004565///beta-galactosidase activity+++GO:0004308///exo-alpha-sialidase activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0042803///protein homodimerization activity","GO:0051413///response to cortisone+++GO:0019388///galactose catabolic process+++GO:0043312///neutrophil degranulation+++GO:0042340///keratan sulfate catabolic process+++GO:0044262///cellular carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0006687///glycosphingolipid metabolic process+++GO:1904016///response to Thyroglobulin triiodothyronine+++GO:0005975///carbohydrate metabolic process+++GO:0006027///glycosaminoglycan catabolic process","galactosidase beta 1","[BGAL_HUMAN|Reviewed]RecName: Full=Beta-galactosidase; EC=3.2.1.23 {ECO:0000269|PubMed:15714521, ECO:0000269|PubMed:19472408, ECO:0000269|PubMed:24737316, ECO:0000269|PubMed:2511208, ECO:0000269|PubMed:25936995, ECO:0000269|PubMed:3143362, ECO:0000269|PubMed:8200356}; AltName: Full=Acid beta-galactosidase; Short=Lactase; AltName: Full=Elastin receptor 1; Flags: Precursor;+++[B7Z6Q5_HUMAN|Unreviewed]RecName: Full=Beta-galactosidase {ECO:0000256|RuleBase:RU000675}; EC=3.2.1.23 {ECO:0000256|RuleBase:RU000675};+++[C9J4G9_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase {ECO:0000313|Ensembl:ENSP00000411813}; Flags: Fragment;+++[C9J539_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase {ECO:0000313|Ensembl:ENSP00000411769}; Flags: Fragment;+++[C9JF15_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase {ECO:0000313|Ensembl:ENSP00000403264}; Flags: Fragment;+++[C9JWX1_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase {ECO:0000313|Ensembl:ENSP00000387989}; Flags: Fragment;+++[E7EQ29_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase {ECO:0000313|Ensembl:ENSP00000305920};+++[F4YK10_HUMAN|Unreviewed]SubName: Full=Galactosidase beta 1 {ECO:0000313|EMBL:ADV75804.1}; EC=3.2.1.23 {ECO:0000313|EMBL:ADV75804.1}; Flags: Fragment;+++[F8WEN1_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase {ECO:0000313|Ensembl:ENSP00000401250};+++[F8WF40_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase {ECO:0000313|Ensembl:ENSP00000407365};"]
[27244,"'SESN1'",319,263,212,264.666666666667,"04115///p53 signaling pathway+++04211///Longevity regulating pathway","H01288///Mosaic variegated aneuploidy (MVA) syndrome",null,null,"GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0061700///GATOR2 complex+++GO:0005829///cytosol+++GO:0031932///TORC2 complex","GO:0070728///leucine binding+++GO:0051920///peroxiredoxin activity+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity","GO:1990253///cellular response to leucine starvation+++GO:0071233///cellular response to leucine+++GO:0016239///positive regulation of macroautophagy+++GO:1904262///negative regulation of TORC1 signaling+++GO:0055114///oxidation-reduction process+++GO:0072593///reactive oxygen species metabolic process+++GO:1901031///regulation of response to reactive oxygen species+++GO:0034198///cellular response to amino acid starvation+++GO:0071230///cellular response to amino acid stimulus+++GO:0098869///cellular oxidant detoxification+++GO:0042149///cellular response to glucose starvation","sestrin 1","[SESN1_HUMAN|Reviewed]RecName: Full=Sestrin-1 {ECO:0000305}; EC=1.11.1.15 {ECO:0000250|UniProtKB:P58004}; AltName: Full=p53-regulated protein PA26 {ECO:0000303|PubMed:9926927};"]
[27289,"'RND1'",3,4,4,3.66666666666667,"04360///Axon guidance",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0032153///cell division site+++GO:0005829///cytosol+++GO:0005938///cell cortex","GO:0005102///signaling receptor binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding","GO:0016322///neuron remodeling+++GO:0007264///small GTPase mediated signal transduction+++GO:0051017///actin filament bundle assembly+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0007266///Rho protein signal transduction+++GO:0008360///regulation of cell shape+++GO:0007015///actin filament organization+++GO:0007162///negative regulation of cell adhesion","Rho family GTPase 1","[RND1_HUMAN|Reviewed]RecName: Full=Rho-related GTP-binding protein Rho6; AltName: Full=Rho family GTPase 1; AltName: Full=Rnd1; Flags: Precursor;+++[F8VXU4_HUMAN|Unreviewed]SubName: Full=Rho-related GTP-binding protein Rho6 {ECO:0000313|Ensembl:ENSP00000449045};+++[H0YHG7_HUMAN|Unreviewed]SubName: Full=Rho-related GTP-binding protein Rho6 {ECO:0000313|Ensembl:ENSP00000447059}; Flags: Fragment;"]
[27314,"'RAB30'",442,289,350,360.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005795///Golgi stack+++GO:0031985///Golgi cisterna+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005801///cis-Golgi network+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005802///trans-Golgi network","GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding","GO:0007030///Golgi organization+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0032482///Rab protein signal transduction","RAB30, member RAS oncogene family","[RAB30_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-30; Flags: Precursor;+++[A8K5R1_HUMAN|Unreviewed]SubName: Full=RAB30, member RAS oncogene family, isoform CRA_a {ECO:0000313|EMBL:EAW75078.1}; SubName: Full=cDNA FLJ78283, highly similar to Homo sapiens RAB30, member RAS oncogene family (RAB30), mRNA {ECO:0000313|EMBL:BAF84065.1}; SubName: Full=cDNA, FLJ92634, Homo sapiens RAB30, member RAS oncogene family (RAB30), mRNA {ECO:0000313|EMBL:BAG35245.1};+++[E9PI18_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000436587}; Flags: Fragment;+++[E9PJQ5_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000435542}; Flags: Fragment;+++[E9PLM3_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000433243};+++[E9PMJ1_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000434953}; Flags: Fragment;+++[E9PNB9_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000437235};+++[E9PPW9_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000436282}; Flags: Fragment;+++[E9PQ07_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000434528}; Flags: Fragment;+++[E9PRF7_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000432336}; Flags: Fragment;+++[E9PRX0_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000434106}; Flags: Fragment;+++[E9PS06_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000432193}; Flags: Fragment;+++[H0YDK7_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-30 {ECO:0000313|Ensembl:ENSP00000433832}; Flags: Fragment;"]
[2734,"'GLG1'",4734,4320,4235,4429.66666666667,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0005794///Golgi apparatus","GO:0005102///signaling receptor binding+++GO:0017134///fibroblast growth factor binding","GO:0060349///bone morphogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0032330///regulation of chondrocyte differentiation+++GO:0050900///leukocyte migration+++GO:0010955///negative regulation of protein processing","golgi glycoprotein 1","[GSLG1_HUMAN|Reviewed]RecName: Full=Golgi apparatus protein 1; AltName: Full=CFR-1; AltName: Full=Cysteine-rich fibroblast growth factor receptor; AltName: Full=E-selectin ligand 1; Short=ESL-1; AltName: Full=Golgi sialoglycoprotein MG-160; Flags: Precursor;+++[H3BM42_HUMAN|Unreviewed]SubName: Full=Golgi apparatus protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW95684.1};+++[H3BQT1_HUMAN|Unreviewed]SubName: Full=Golgi apparatus protein 1 {ECO:0000313|Ensembl:ENSP00000455927}; Flags: Fragment;+++[H3BQU9_HUMAN|Unreviewed]SubName: Full=Golgi apparatus protein 1 {ECO:0000313|Ensembl:ENSP00000455950};+++[H3BRD8_HUMAN|Unreviewed]SubName: Full=Golgi apparatus protein 1 {ECO:0000313|Ensembl:ENSP00000456195}; Flags: Fragment;"]
[27340,"'UTP20'",525,360,445,443.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0032040///small-subunit processome+++GO:0030688///preribosome, small subunit precursor+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0030686///90S preribosome+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000472///endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0008285///negative regulation of cell proliferation+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","UTP20, small subunit processome component","[UTP20_HUMAN|Reviewed]RecName: Full=Small subunit processome component 20 homolog; AltName: Full=Down-regulated in metastasis protein; AltName: Full=Novel nucleolar protein 73; Short=NNP73; AltName: Full=Protein Key-1A6;"]
[2739,"'GLO1'",1002,915,1100,1005.66666666667,"00620///Pyruvate metabolism",null,null,"R02530///(R)-S-Lactoylglutathione methylglyoxal-lyase (isomerizing)   (R)-S-Lactoylglutathione <=> Glutathione + Methylglyoxal","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0004462///lactoylglutathione lyase activity+++GO:0016829///lyase activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0006749///glutathione metabolic process+++GO:0030316///osteoclast differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0009438///methylglyoxal metabolic process+++GO:0006090///pyruvate metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II","glyoxalase I","[LGUL_HUMAN|Reviewed]RecName: Full=Lactoylglutathione lyase; EC=4.4.1.5; AltName: Full=Aldoketomutase; AltName: Full=Glyoxalase I; Short=Glx I; AltName: Full=Ketone-aldehyde mutase; AltName: Full=Methylglyoxalase; AltName: Full=S-D-lactoylglutathione methylglyoxal lyase;+++[V9HW62_HUMAN|Unreviewed]RecName: Full=Lactoylglutathione lyase {ECO:0000256|RuleBase:RU361179}; EC=4.4.1.5 {ECO:0000256|RuleBase:RU361179}; AltName: Full=Glyoxalase I {ECO:0000256|RuleBase:RU361179};+++[X5DNM4_HUMAN|Unreviewed]RecName: Full=Lactoylglutathione lyase {ECO:0000256|RuleBase:RU361179}; EC=4.4.1.5 {ECO:0000256|RuleBase:RU361179}; AltName: Full=Glyoxalase I {ECO:0000256|RuleBase:RU361179}; Flags: Fragment;"]
[2746,"'GLUD1'",786.19,690.59,674.2,716.993333333333,"04217///Necroptosis+++00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++01100///Metabolic pathways+++00471///D-Glutamine and D-glutamate metabolism+++01200///Carbon metabolism+++04964///Proximal tubule bicarbonate reclamation+++00910///Nitrogen metabolism","H01267///Familial hyperinsulinemic hypoglycemia (HHF)+++H01400///Secondary hyperammonemia","M00740///Methylaspartate cycle","R00248///L-Glutamate:NADP+ oxidoreductase (deaminating)   L-Glutamate + NADP+ + H2O <=> 2-Oxoglutarate + Ammonia + NADPH + H++++R00243///L-glutamate:NAD+ oxidoreductase (deaminating)   L-Glutamate + NAD+ + H2O <=> 2-Oxoglutarate + Ammonia + NADH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm","GO:0016639///oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0070403///NAD+ binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0043531///ADP binding+++GO:0004353///glutamate dehydrogenase [NAD(P)+] activity+++GO:0070728///leucine binding+++GO:0016491///oxidoreductase activity+++GO:0005525///GTP binding+++GO:0004352///glutamate dehydrogenase (NAD+) activity","GO:0006538///glutamate catabolic process+++GO:0055114///oxidation-reduction process+++GO:0032024///positive regulation of insulin secretion+++GO:0021762///substantia nigra development+++GO:0006520///cellular amino acid metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0006537///glutamate biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0072350///tricarboxylic acid metabolic process","glutamate dehydrogenase 1","[DHE3_HUMAN|Reviewed]RecName: Full=Glutamate dehydrogenase 1, mitochondrial; Short=GDH 1; EC=1.4.1.3; Flags: Precursor;+++[E9KL48_HUMAN|Unreviewed]SubName: Full=Epididymis tissue sperm binding protein Li 18mP {ECO:0000313|EMBL:ADU87647.1}; SubName: Full=Glutamate dehydrogenase 1, isoform CRA_d {ECO:0000313|EMBL:EAW80304.1};+++[Q14400_HUMAN|Unreviewed]SubName: Full=GLUD1 protein {ECO:0000313|EMBL:AAA52524.1}; Flags: Fragment;+++[Q9UQV0_HUMAN|Unreviewed]SubName: Full=Glutamate dehydrogenase (NAD(P)+) {ECO:0000313|EMBL:CAA46996.1}; EC=1.4.1.3 {ECO:0000313|EMBL:CAA46996.1}; Flags: Fragment;"]
[2781,"'GNAZ'",622,596,663,627,"04730///Long-term depression",{"$nulls":3},"GO:0044297///cell body+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005834///heterotrimeric G-protein complex+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0030425///dendrite","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0031821///G protein-coupled serotonin receptor binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003924///GTPase activity+++GO:0019001///guanyl nucleotide binding","GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0006457///protein folding+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","G protein subunit alpha z","[GNAZ_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein G(z) subunit alpha; AltName: Full=G(x) alpha chain; AltName: Full=Gz-alpha;+++[Q8IY73_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein (G protein), alpha z polypeptide {ECO:0000313|EMBL:AAH37333.1};+++[Q8N652_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein (G protein), alpha z polypeptide {ECO:0000313|EMBL:AAH26342.1};"]
[2797,"'GNRH2'",4,1,4,3,"04912///GnRH signaling pathway","H00255///Hypogonadotropic hypogonadism",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0031530///gonadotropin-releasing hormone receptor binding+++GO:0005183///gonadotropin hormone-releasing hormone activity+++GO:0005179///hormone activity","GO:0007165///signal transduction+++GO:0000003///reproduction+++GO:0007275///multicellular organism development+++GO:0010469///regulation of signaling receptor activity+++GO:0007186///G protein-coupled receptor signaling pathway","gonadotropin releasing hormone 2","[GON2_HUMAN|Reviewed]RecName: Full=Progonadoliberin-2; AltName: Full=Progonadoliberin II; Contains: RecName: Full=Gonadoliberin-2; AltName: Full=Gonadoliberin II; AltName: Full=Gonadotropin-releasing hormone II; Short=GnRH II; AltName: Full=Luliberin II; AltName: Full=Luteinizing hormone-releasing hormone II; Short=LH-RH II; Contains: RecName: Full=GnRH-associated peptide 2; AltName: Full=GnRH-associated peptide II; Flags: Precursor;"]
[2820,"'GPD2'",120,89,121,110,"00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites",null,null,"R00848///sn-Glycerol-3-phosphate:(acceptor) 2-oxidoreductase   sn-Glycerol 3-phosphate + FAD <=> Glycerone phosphate + FADH2","GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0009331///glycerol-3-phosphate dehydrogenase complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0004368///glycerol-3-phosphate dehydrogenase (quinone) activity+++GO:0052591///sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity+++GO:0004367///glycerol-3-phosphate dehydrogenase [NAD+] activity+++GO:0052590///sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity+++GO:0016491///oxidoreductase activity","GO:0019563///glycerol catabolic process+++GO:0035264///multicellular organism growth+++GO:0043010///camera-type eye development+++GO:0006127///glycerophosphate shuttle+++GO:0006072///glycerol-3-phosphate metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006094///gluconeogenesis+++GO:0046168///glycerol-3-phosphate catabolic process","glycerol-3-phosphate dehydrogenase 2","[GPDM_HUMAN|Reviewed]RecName: Full=Glycerol-3-phosphate dehydrogenase, mitochondrial; Short=GPD-M; Short=GPDH-M; EC=1.1.5.3; AltName: Full=mtGPD; Flags: Precursor;+++[A0A0S2Z3S0_HUMAN|Unreviewed]RecName: Full=Glycerol-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361217}; EC=1.1.5.3 {ECO:0000256|RuleBase:RU361217}; Flags: Fragment;+++[E7EM56_HUMAN|Unreviewed]RecName: Full=Glycerol-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361217}; EC=1.1.5.3 {ECO:0000256|RuleBase:RU361217}; Flags: Fragment;+++[E9PDK4_HUMAN|Unreviewed]SubName: Full=Glycerol-3-phosphate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000408522};+++[F5GYK7_HUMAN|Unreviewed]RecName: Full=Glycerol-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361217}; EC=1.1.5.3 {ECO:0000256|RuleBase:RU361217};+++[Q53RD0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein GPD2 {ECO:0000313|EMBL:AAY24073.1}; Flags: Fragment;+++[Q53T76_HUMAN|Unreviewed]RecName: Full=Glycerol-3-phosphate dehydrogenase {ECO:0000256|RuleBase:RU361217}; EC=1.1.5.3 {ECO:0000256|RuleBase:RU361217}; Flags: Fragment;"]
[2827,"'GPR3'",51,50,27,42.6666666666667,"04666///Fc gamma R-mediated phagocytosis+++05231///Choline metabolism in cancer+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++05131///Shigellosis+++04520///Adherens junction+++05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0004930///G protein-coupled receptor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0040020///regulation of meiotic nuclear division+++GO:0120162///positive regulation of cold-induced thermogenesis","G protein-coupled receptor 3","[GPR3_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor 3; AltName: Full=ACCA orphan receptor;+++[F1DAM5_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 3 {ECO:0000313|EMBL:ADZ17396.1};"]
[283208,"'P4HA3'",157,164,141,154,"01100///Metabolic pathways+++00330///Arginine and proline metabolism","H02041///Myopia",null,"R01252///L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating)   L-Proline + 2-Oxoglutarate + Oxygen <=> Hydroxyproline + Succinate + CO2","GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen+++GO:0004656///procollagen-proline 4-dioxygenase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0031418///L-ascorbic acid binding+++GO:0005506///iron ion binding","GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0019511///peptidyl-proline hydroxylation+++GO:0055114///oxidation-reduction process","prolyl 4-hydroxylase subunit alpha 3","[P4HA3_HUMAN|Reviewed]RecName: Full=Prolyl 4-hydroxylase subunit alpha-3; Short=4-PH alpha-3; EC=1.14.11.2; AltName: Full=Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3; Flags: Precursor;+++[E9PM97_HUMAN|Unreviewed]SubName: Full=Prolyl 4-hydroxylase subunit alpha-3 {ECO:0000313|Ensembl:ENSP00000431227};+++[H0YCC3_HUMAN|Unreviewed]SubName: Full=Prolyl 4-hydroxylase subunit alpha-3 {ECO:0000313|Ensembl:ENSP00000431350}; Flags: Fragment;"]
[283298,"'OLFML1'",33,36,62,43.6666666666667,{"$nulls":4},"GO:0005576///extracellular region",null,null,"olfactomedin like 1","[OLFL1_HUMAN|Reviewed]RecName: Full=Olfactomedin-like protein 1; Flags: Precursor;+++[E9PKN7_HUMAN|Unreviewed]SubName: Full=Olfactomedin-like protein 1 {ECO:0000313|Ensembl:ENSP00000431558}; Flags: Fragment;+++[E9PN44_HUMAN|Unreviewed]SubName: Full=Olfactomedin-like protein 1 {ECO:0000313|Ensembl:ENSP00000434813};+++[Q5HYE3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686H1812 {ECO:0000313|EMBL:CAI46097.1};"]
[283514,"'SIAH3'",5,2,1,2.66666666666667,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0061630///ubiquitin protein ligase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding","GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0031647///regulation of protein stability+++GO:0007275///multicellular organism development+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1903215///negative regulation of protein targeting to mitochondrion","siah E3 ubiquitin protein ligase family member 3","[SIAH3_HUMAN|Reviewed]RecName: Full=Seven in absentia homolog 3; Short=Siah-3;"]
[283638,"'CEP170B'",2155,2061,2121,2112.33333333333,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005874///microtubule",null,null,"centrosomal protein 170B","[C170B_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 170 kDa protein B; AltName: Full=Centrosomal protein 170B; Short=Cep170B;+++[J3KQR7_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa protein B {ECO:0000313|Ensembl:ENSP00000407238};"]
[283991,"'UBALD2'",443,501,513,485.666666666667,{"$nulls":7},"UBA like domain containing 2","[UBAD2_HUMAN|Reviewed]RecName: Full=UBA-like domain-containing protein 2;+++[K7EMI7_HUMAN|Unreviewed]SubName: Full=UBA-like domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000466518};+++[K7ERK7_HUMAN|Unreviewed]SubName: Full=UBA-like domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000468297}; Flags: Fragment;"]
[284023,"'RNF227'",20.01,32.46,42.83,31.7666666666667,{"$nulls":5},"GO:0046872///metal ion binding",null,"ring finger protein 227","[RN227_HUMAN|Reviewed]RecName: Full=RING finger protein 227 {ECO:0000305}; AltName: Full=Long intergenic non-protein coding RNA 2581 {ECO:0000312|HGNC:HGNC:27571};+++[A0A1B0GTZ6_HUMAN|Unreviewed]SubName: Full=RING finger protein 227 {ECO:0000313|Ensembl:ENSP00000489902};+++[A0A2Y9D085_HUMAN|Unreviewed]SubName: Full=RING finger protein 227 {ECO:0000313|Ensembl:ENSP00000491639};"]
[284306,"'ZNF547'",27.27,28,23.33,26.2,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006888///ER to Golgi vesicle-mediated transport","zinc finger protein 547","[ZN547_HUMAN|Reviewed]RecName: Full=Zinc finger protein 547;+++[M0QX63_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 547 {ECO:0000313|Ensembl:ENSP00000468929}; Flags: Fragment;+++[M0QYW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 547 {ECO:0000313|Ensembl:ENSP00000470111}; Flags: Fragment;+++[M0QZZ8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 547 {ECO:0000313|Ensembl:ENSP00000470884};"]
[284339,"'TMEM145'",6,12,12,10,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone","transmembrane protein 145","[TM145_HUMAN|Reviewed]RecName: Full=Transmembrane protein 145;+++[M0QZK1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 145 {ECO:0000313|Ensembl:ENSP00000470602}; Flags: Fragment;+++[M0QZX2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 145 {ECO:0000313|Ensembl:ENSP00000470827};"]
[284371,"'ZNF841'",168,120,109,132.333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 841","[ZN841_HUMAN|Reviewed]RecName: Full=Zinc finger protein 841;+++[M0QYV6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 841 {ECO:0000313|Ensembl:ENSP00000470100}; Flags: Fragment;+++[M0R0F3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 841 {ECO:0000313|Ensembl:ENSP00000471190}; Flags: Fragment;"]
[284613,"'CYB561D1'",290,266,278,278,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding","GO:0055114///oxidation-reduction process","cytochrome b561 family member D1","[C56D1_HUMAN|Reviewed]RecName: Full=Cytochrome b561 domain-containing protein 1;+++[B4DR38_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58930, highly similar to Cytochrome b561 domain-containing protein 1 {ECO:0000313|EMBL:BAG61150.1};+++[B4E0W0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58969, highly similar to Cytochrome b561 domain-containing protein 1 {ECO:0000313|EMBL:BAG64572.1};+++[E9PIJ2_HUMAN|Unreviewed]SubName: Full=Cytochrome b561 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000435819};+++[E9PIK3_HUMAN|Unreviewed]SubName: Full=Cytochrome b561 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000435802};+++[E9PM70_HUMAN|Unreviewed]SubName: Full=Cytochrome b561 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000433095};+++[E9PQU0_HUMAN|Unreviewed]SubName: Full=Cytochrome b561 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000434344};+++[Q6ZQS1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ44753 fis, clone BRACE3030538, weakly similar to Homo sapiens tumor suppressor 101F6 (101F6) {ECO:0000313|EMBL:BAC86652.1}; SubName: Full=cDNA FLJ45666 fis, clone CTONG3001605, weakly similar to Homo sapiens tumor suppressor 101F6 (101F6) {ECO:0000313|EMBL:BAC87612.1};"]
[284759,"'SIRPB2'",2,1,1,1.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"signal regulatory protein beta 2","[SIRB2_HUMAN|Reviewed]RecName: Full=Signal-regulatory protein beta-2; Short=SIRP-beta-2; AltName: Full=Protein tyrosine phosphatase non-receptor type substrate 1-like 3; AltName: Full=Protein tyrosine phosphatase non-receptor type substrate protein; Flags: Precursor;+++[B3KTG0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38180 fis, clone FCBBF1000121, weakly similar to Homo sapiens SHPS-1 {ECO:0000313|EMBL:BAG53072.1};+++[F2Z2Y9_HUMAN|Unreviewed]SubName: Full=Signal-regulatory protein beta-2 {ECO:0000313|Ensembl:ENSP00000432656};+++[V9GYW8_HUMAN|Unreviewed]SubName: Full=Signal-regulatory protein beta-2 {ECO:0000313|Ensembl:ENSP00000477149};"]
[285190,"'RGPD4'",3.39,2.67,12.37,6.14333333333333,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005813///centrosome+++GO:0005643///nuclear pore+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005096///GTPase activator activity+++GO:0008536///Ran GTPase binding","GO:0006607///NLS-bearing protein import into nucleus+++GO:0046907///intracellular transport+++GO:0043547///positive regulation of GTPase activity","RANBP2-like and GRIP domain containing 4","[RGPD4_HUMAN|Reviewed]RecName: Full=RanBP2-like and GRIP domain-containing protein 4;"]
[285331,"'CCDC66'",124,129,142,131.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0001917///photoreceptor inner segment+++GO:0005815///microtubule organizing center+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0034451///centriolar satellite+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0036064///ciliary basal body+++GO:0005874///microtubule+++GO:0005813///centrosome+++GO:0035869///ciliary transition zone+++GO:0001750///photoreceptor outer segment","GO:0042803///protein homodimerization activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0001578///microtubule bundle formation+++GO:0060271///cilium assembly+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0046548///retinal rod cell development+++GO:1903564///regulation of protein localization to cilium+++GO:0001895///retina homeostasis+++GO:0030030///cell projection organization","coiled-coil domain containing 66","[CCD66_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 66 {ECO:0000305};+++[C9JYB8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 66 {ECO:0000313|Ensembl:ENSP00000401451}; Flags: Fragment;+++[F2Z2K6_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 66 {ECO:0000313|Ensembl:ENSP00000390652};+++[F8WB87_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 66 {ECO:0000313|Ensembl:ENSP00000410510};+++[F8WCY0_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 66 {ECO:0000313|Ensembl:ENSP00000343840};+++[F8WDJ0_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 66 {ECO:0000313|Ensembl:ENSP00000420192};"]
[285533,"'RNF175'",2,5,5,4,"05146///Amoebiasis+++04151///PI3K-Akt signaling pathway+++05140///Leishmaniasis+++05142///Chagas disease (American trypanosomiasis)+++04145///Phagosome+++05145///Toxoplasmosis+++05162///Measles+++05323///Rheumatoid arthritis+++05161///Hepatitis B+++05134///Legionellosis+++04620///Toll-like receptor signaling pathway+++05144///Malaria+++05168///Herpes simplex infection+++05205///Proteoglycans in cancer+++05321///Inflammatory bowel disease (IBD)+++05152///Tuberculosis","H01358///Atopic dermatitis+++H00344///Leprosy","M00686///Toll-like receptor signaling",null,"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0046872///metal ion binding","GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0016567///protein ubiquitination","ring finger protein 175","[RN175_HUMAN|Reviewed]RecName: Full=RING finger protein 175;+++[D6RAJ1_HUMAN|Unreviewed]SubName: Full=RING finger protein 175 {ECO:0000313|Ensembl:ENSP00000421761};+++[D6RB06_HUMAN|Unreviewed]SubName: Full=RING finger protein 175 {ECO:0000313|Ensembl:ENSP00000424563};+++[D6RB46_HUMAN|Unreviewed]SubName: Full=RING finger protein 175 {ECO:0000313|Ensembl:ENSP00000424430};+++[D6RID2_HUMAN|Unreviewed]SubName: Full=RING finger protein 175 {ECO:0000313|Ensembl:ENSP00000427472}; Flags: Fragment;"]
[285676,"'ZNF454'",67.22,75.08,57.53,66.61,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 454","[ZN454_HUMAN|Reviewed]RecName: Full=Zinc finger protein 454;"]
[285989,"'ZNF789'",160.56,137.08,143,146.88,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 789","[ZN789_HUMAN|Reviewed]RecName: Full=Zinc finger protein 789;+++[C9J3R7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000417227};+++[C9J487_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000405206};+++[C9JUE3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000419500};+++[F8WEN0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000401255};"]
[286257,"'PAXX'",191,230,220,213.666666666667,{"$nulls":4},"GO:0043564///Ku70:Ku80 complex+++GO:0035861///site of double-strand break+++GO:0070419///nonhomologous end joining complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity","GO:0006281///DNA repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051103///DNA ligation involved in DNA repair","PAXX, non-homologous end joining factor","[PAXX_HUMAN|Reviewed]RecName: Full=Protein PAXX {ECO:0000305}; AltName: Full=Paralog of XRCC4 and XLF {ECO:0000303|PubMed:25574025}; AltName: Full=XRCC4-like small protein {ECO:0000303|PubMed:25941166};"]
[286826,"'LIN9'",23,31,30,28,"04218///Cellular senescence",{"$nulls":3},"GO:0015030///Cajal body+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0017053///transcriptional repressor complex+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0071164///RNA trimethylguanosine synthase activity+++GO:0003677///DNA binding+++GO:0008173///RNA methyltransferase activity","GO:0019216///regulation of lipid metabolic process+++GO:0036261///7-methylguanosine cap hypermethylation+++GO:0001510///RNA methylation+++GO:0009452///7-methylguanosine RNA capping+++GO:0071897///DNA biosynthetic process+++GO:0032259///methylation+++GO:0022613///ribonucleoprotein complex biogenesis+++GO:0000387///spliceosomal snRNP assembly+++GO:0000003///reproduction+++GO:0051726///regulation of cell cycle+++GO:0006351///transcription, DNA-templated+++GO:0007049///cell cycle","lin-9 DREAM MuvB core complex component","[LIN9_HUMAN|Reviewed]RecName: Full=Protein lin-9 homolog; Short=HuLin-9; Short=hLin-9; AltName: Full=Beta subunit-associated regulator of apoptosis; AltName: Full=TUDOR gene similar protein; AltName: Full=Type I interferon receptor beta chain-associated protein; AltName: Full=pRB-associated protein;+++[B1B047_HUMAN|Unreviewed]SubName: Full=Protein lin-9 homolog {ECO:0000313|Ensembl:ENSP00000352515}; Flags: Fragment;+++[C9J5J4_HUMAN|Unreviewed]SubName: Full=Protein lin-9 homolog {ECO:0000313|Ensembl:ENSP00000418489};+++[E5RJW7_HUMAN|Unreviewed]SubName: Full=Trimethylguanosine synthase {ECO:0000313|Ensembl:ENSP00000430467};+++[H0Y322_HUMAN|Unreviewed]SubName: Full=Protein lin-9 homolog {ECO:0000313|Ensembl:ENSP00000355773}; Flags: Fragment;+++[H7C4T7_HUMAN|Unreviewed]SubName: Full=Protein lin-9 homolog {ECO:0000313|Ensembl:ENSP00000418121}; Flags: Fragment;+++[L8E9Q2_HUMAN|Unreviewed]SubName: Full=Alternative protein LIN9 {ECO:0000313|EMBL:CCQ43889.1};+++[Q6P142_HUMAN|Unreviewed]SubName: Full=LIN9 protein {ECO:0000313|EMBL:AAH65302.1}; Flags: Fragment;"]
[2887,"'GRB10'",1672,1475,1649,1598.66666666667,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005158///insulin receptor binding+++GO:0005515///protein binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0042802///identical protein binding","GO:0009967///positive regulation of signal transduction+++GO:0008286///insulin receptor signaling pathway+++GO:0032868///response to insulin+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0048009///insulin-like growth factor receptor signaling pathway+++GO:0007165///signal transduction+++GO:0042327///positive regulation of phosphorylation+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0042326///negative regulation of phosphorylation+++GO:0007411///axon guidance+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0046325///negative regulation of glucose import","growth factor receptor bound protein 10","[GRB10_HUMAN|Reviewed]RecName: Full=Growth factor receptor-bound protein 10; AltName: Full=GRB10 adapter protein; AltName: Full=Insulin receptor-binding protein Grb-IR;+++[A0A2R8Y6Q4_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 10 {ECO:0000313|Ensembl:ENSP00000495397};+++[A0A2R8YCL1_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 10 {ECO:0000313|Ensembl:ENSP00000493728};+++[C9JTW6_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 10 {ECO:0000313|Ensembl:ENSP00000413023}; Flags: Fragment;+++[H7C3B9_HUMAN|Unreviewed]SubName: Full=Growth factor receptor-bound protein 10 {ECO:0000313|Ensembl:ENSP00000410920}; Flags: Fragment;+++[Q75M93_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein GRB10 {ECO:0000313|EMBL:AAS07426.1}; Flags: Fragment;+++[Q75MT1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein GRB10 {ECO:0000313|EMBL:AAS00377.1}; Flags: Fragment;"]
[28962,"'OSTM1'",752,585,651,662.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane",null,"GO:0030316///osteoclast differentiation","osteoclastogenesis associated transmembrane protein 1","[OSTM1_HUMAN|Reviewed]RecName: Full=Osteopetrosis-associated transmembrane protein 1; AltName: Full=Chloride channel 7 beta subunit; Flags: Precursor;+++[A0A0A0MSP4_HUMAN|Unreviewed]SubName: Full=Osteopetrosis-associated transmembrane protein 1 {ECO:0000313|Ensembl:ENSP00000398556}; Flags: Fragment;+++[A0A0S2VEL3_HUMAN|Unreviewed]SubName: Full=Osteopetrosis associated transmembrane protein 1 {ECO:0000313|EMBL:ALP82470.1}; Flags: Fragment;"]
[2898,"'GRIK2'",69,38,38,48.3333333333333,"04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse","H00768///Nonsyndromic autosomal recessive mental retardation (NS-ARMR)",null,null,"GO:0005887///integral component of plasma membrane+++GO:0043195///terminal bouton+++GO:0045211///postsynaptic membrane+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0008328///ionotropic glutamate receptor complex+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0032839///dendrite cytoplasm+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0030424///axon","GO:0015276///ligand-gated ion channel activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0004970///ionotropic glutamate receptor activity+++GO:0042802///identical protein binding+++GO:0015277///kainate selective glutamate receptor activity+++GO:0042803///protein homodimerization activity+++GO:0005234///extracellularly glutamate-gated ion channel activity+++GO:0008066///glutamate receptor activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0030165///PDZ domain binding","GO:0043525///positive regulation of neuron apoptotic process+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0046328///regulation of JNK cascade+++GO:0006886///intracellular protein transport+++GO:0043113///receptor clustering+++GO:0007215///glutamate receptor signaling pathway+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0051967///negative regulation of synaptic transmission, glutamatergic+++GO:0019228///neuronal action potential+++GO:0006874///cellular calcium ion homeostasis+++GO:0042391///regulation of membrane potential+++GO:0035249///synaptic transmission, glutamatergic+++GO:0051402///neuron apoptotic process+++GO:0007268///chemical synaptic transmission+++GO:0050806///positive regulation of synaptic transmission+++GO:0060080///inhibitory postsynaptic potential+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0001662///behavioral fear response+++GO:0060079///excitatory postsynaptic potential","glutamate ionotropic receptor kainate type subunit 2","[GRIK2_HUMAN|Reviewed]RecName: Full=Glutamate receptor ionotropic, kainate 2; Short=GluK2; AltName: Full=Excitatory amino acid receptor 4; Short=EAA4; AltName: Full=Glutamate receptor 6; Short=GluR-6; Short=GluR6; Flags: Precursor;+++[A8K0H7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77447, highly similar to Homo sapiens glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF82231.1};+++[Q8IY40_HUMAN|Unreviewed]SubName: Full=GRIK2 protein {ECO:0000313|EMBL:AAH37954.1};"]
[2900,"'GRIK4'",324,330,529,394.333333333333,"04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse",{"$nulls":3},"GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0045211///postsynaptic membrane+++GO:0099055///integral component of postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane","GO:0004970///ionotropic glutamate receptor activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0008066///glutamate receptor activity+++GO:0038023///signaling receptor activity+++GO:0005216///ion channel activity","GO:0006811///ion transport+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007215///glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0034220///ion transmembrane transport+++GO:0007268///chemical synaptic transmission","glutamate ionotropic receptor kainate type subunit 4","[GRIK4_HUMAN|Reviewed]RecName: Full=Glutamate receptor ionotropic, kainate 4; Short=GluK4; AltName: Full=Excitatory amino acid receptor 1; Short=EAA1; AltName: Full=Glutamate receptor KA-1; Short=KA1; Flags: Precursor;+++[A6H8K8_HUMAN|Unreviewed]SubName: Full=GRIK4 protein {ECO:0000313|EMBL:AAI46653.1};+++[B2RAP6_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95040, highly similar to Homo sapiens glutamate receptor, ionotropic, kainate 4 (GRIK4), mRNA {ECO:0000313|EMBL:BAG36943.1};"]
[29068,"'ZBTB44'",291,235,233,253,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 44","[ZBT44_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 44; AltName: Full=BTB/POZ domain-containing protein 15; AltName: Full=Zinc finger protein 851;+++[A0A0A0MTE9_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000435413}; Flags: Fragment;+++[H0YCZ0_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000432558}; Flags: Fragment;+++[H0YEM9_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000436187}; Flags: Fragment;+++[H7BY22_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 44 {ECO:0000313|Ensembl:ENSP00000350574};"]
[29090,"'TIMM21'",238,254,302,264.666666666667,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0032981///mitochondrial respiratory chain complex I assembly","translocase of inner mitochondrial membrane 21","[TIM21_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim21; AltName: Full=TIM21-like protein, mitochondrial; Flags: Precursor;+++[A8K1K8_HUMAN|Unreviewed]SubName: Full=Chromosome 18 open reading frame 55, isoform CRA_b {ECO:0000313|EMBL:EAW66541.1}; SubName: Full=cDNA FLJ78000 {ECO:0000313|EMBL:BAF82612.1}; SubName: Full=cDNA, FLJ94576 {ECO:0000313|EMBL:BAG36655.1};+++[J3KRJ3_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim21 {ECO:0000313|Ensembl:ENSP00000462028};+++[J3QRI1_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim21 {ECO:0000313|Ensembl:ENSP00000464228}; Flags: Fragment;"]
[29104,"'N6AMT1'",160,137,130,142.333333333333,{"$nulls":4},"GO:0035657///eRF1 methyltransferase complex+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0008276///protein methyltransferase activity+++GO:0036009///protein-glutamine N-methyltransferase activity+++GO:0030792///methylarsonite methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0009007///site-specific DNA-methyltransferase (adenine-specific) activity","GO:0018364///peptidyl-glutamine methylation+++GO:0018872///arsonoacetate metabolic process+++GO:0032775///DNA methylation on adenine+++GO:0009404///toxin metabolic process+++GO:0032259///methylation+++GO:0030307///positive regulation of cell growth","N-6 adenine-specific DNA methyltransferase 1","[N6MT1_HUMAN|Reviewed]RecName: Full=Methyltransferase N6AMT1 {ECO:0000305}; AltName: Full=HemK methyltransferase family member 2 {ECO:0000303|PubMed:18539146}; Short=M.HsaHemK2P; AltName: Full=Methylarsonite methyltransferase N6AMT1; EC=2.1.1.- {ECO:0000269|PubMed:21193388, ECO:0000269|PubMed:25997655}; AltName: Full=N(6)-adenine-specific DNA methyltransferase 1 {ECO:0000303|PubMed:30017583}; EC=2.1.1.72 {ECO:0000269|PubMed:30017583}; AltName: Full=Protein N(5)-glutamine methyltransferase {ECO:0000305}; EC=2.1.1.- {ECO:0000269|PubMed:18539146};"]
[29108,"'PYCARD'",72,83,73,76,"04621///NOD-like receptor signaling pathway+++05134///Legionellosis+++04623///Cytosolic DNA-sensing pathway+++04625///C-type lectin receptor signaling pathway+++05164///Influenza A+++04217///Necroptosis+++05132///Salmonella infection+++05133///Pertussis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0008385///IkappaB kinase complex+++GO:0032991///protein-containing complex+++GO:0072558///NLRP1 inflammasome complex+++GO:0005576///extracellular region+++GO:0097169///AIM2 inflammasome complex+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0035578///azurophil granule lumen+++GO:0034774///secretory granule lumen+++GO:0072559///NLRP3 inflammasome complex+++GO:0005783///endoplasmic reticulum","GO:0070700///BMP receptor binding+++GO:0032090///Pyrin domain binding+++GO:0005138///interleukin-6 receptor binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0005515///protein binding+++GO:0017024///myosin I binding+++GO:0005523///tropomyosin binding+++GO:0044325///ion channel binding+++GO:0046983///protein dimerization activity+++GO:0019899///enzyme binding+++GO:0002020///protease binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0042803///protein homodimerization activity+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042802///identical protein binding","GO:0032760///positive regulation of tumor necrosis factor production+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0009617///response to bacterium+++GO:0006508///proteolysis+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0032688///negative regulation of interferon-beta production+++GO:0051260///protein homooligomerization+++GO:0002588///positive regulation of antigen processing and presentation of peptide antigen via MHC class II+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0002376///immune system process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0043087///regulation of GTPase activity+++GO:2000406///positive regulation of T cell migration+++GO:0032755///positive regulation of interleukin-6 production+++GO:2001242///regulation of intrinsic apoptotic signaling pathway+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0031647///regulation of protein stability+++GO:0044351///macropinocytosis+++GO:0032611///interleukin-1 beta production+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0043312///neutrophil degranulation+++GO:0002218///activation of innate immune response+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0090197///positive regulation of chemokine secretion+++GO:2001181///positive regulation of interleukin-10 secretion+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0010506///regulation of autophagy+++GO:0045087///innate immune response+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:2000778///positive regulation of interleukin-6 secretion+++GO:2001056///positive regulation of cysteine-type endopeptidase activity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0050870///positive regulation of T cell activation+++GO:0002821///positive regulation of adaptive immune response+++GO:0051607///defense response to virus+++GO:0071347///cellular response to interleukin-1+++GO:0050829///defense response to Gram-negative bacterium+++GO:0043065///positive regulation of apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:2000484///positive regulation of interleukin-8 secretion+++GO:1900016///negative regulation of cytokine production involved in inflammatory response+++GO:0032729///positive regulation of interferon-gamma production+++GO:0050766///positive regulation of phagocytosis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0030838///positive regulation of actin filament polymerization+++GO:0006954///inflammatory response+++GO:0050727///regulation of inflammatory response+++GO:0001773///myeloid dendritic cell activation+++GO:0007165///signal transduction+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0002230///positive regulation of defense response to virus by host+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage","PYD and CARD domain containing","[ASC_HUMAN|Reviewed]RecName: Full=Apoptosis-associated speck-like protein containing a CARD; Short=hASC; AltName: Full=Caspase recruitment domain-containing protein 5; AltName: Full=PYD and CARD domain-containing protein; AltName: Full=Target of methylation-induced silencing 1;+++[H3BP42_HUMAN|Unreviewed]SubName: Full=Apoptosis-associated speck-like protein-containing a CARD {ECO:0000313|Ensembl:ENSP00000455141}; Flags: Fragment;"]
[2921,"'CXCL3'",0,2,1,1,"04668///TNF signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05132///Salmonella infection+++04657///IL-17 signaling pathway+++04062///Chemokine signaling pathway+++05134///Legionellosis+++04060///Cytokine-cytokine receptor interaction+++04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005125///cytokine activity+++GO:0008009///chemokine activity","GO:0030595///leukocyte chemotaxis+++GO:0006935///chemotaxis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006954///inflammatory response+++GO:0006955///immune response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0030593///neutrophil chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0006952///defense response+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide","C-X-C motif chemokine ligand 3","[CXCL3_HUMAN|Reviewed]RecName: Full=C-X-C motif chemokine 3; AltName: Full=GRO-gamma(1-73); AltName: Full=Growth-regulated protein gamma; Short=GRO-gamma; AltName: Full=Macrophage inflammatory protein 2-beta; Short=MIP2-beta; Contains: RecName: Full=GRO-gamma(5-73); Flags: Precursor;"]
[2932,"'GSK3B'",1181,880,989,1016.66666666667,"05210///Colorectal cancer+++04341///Hedgehog signaling pathway - fly+++04711///Circadian rhythm - fly+++04910///Insulin signaling pathway+++04917///Prolactin signaling pathway+++04150///mTOR signaling pathway+++04360///Axon guidance+++04657///IL-17 signaling pathway+++05215///Prostate cancer+++04310///Wnt signaling pathway+++05166///HTLV-I infection+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05162///Measles+++04662///B cell receptor signaling pathway+++04151///PI3K-Akt signaling pathway+++05213///Endometrial cancer+++04390///Hippo signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04728///Dopaminergic synapse+++04062///Chemokine signaling pathway+++04110///Cell cycle+++05163///Human cytomegalovirus infection+++05225///Hepatocellular carcinoma+++04340///Hedgehog signaling pathway+++05160///Hepatitis C+++04012///ErbB signaling pathway+++05224///Breast cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05010///Alzheimer's disease+++05164///Influenza A+++04934///Cushing's syndrome+++04931///Insulin resistance+++04916///Melanogenesis+++04660///T cell receptor signaling pathway+++04722///Neurotrophin signaling pathway+++05217///Basal cell carcinoma+++04510///Focal adhesion+++05200///Pathways in cancer+++05226///Gastric cancer",null,"M00677///Wnt signaling",null,"GO:0016020///membrane+++GO:0030425///dendrite+++GO:0098794///postsynapse+++GO:0098978///glutamatergic synapse+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0030877///beta-catenin destruction complex+++GO:0030424///axon+++GO:1990909///Wnt signalosome+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0019901///protein kinase binding+++GO:0051059///NF-kappaB binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0050321///tau-protein kinase activity+++GO:0005515///protein binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0002039///p53 binding+++GO:0002020///protease binding+++GO:0048156///tau protein binding+++GO:0008013///beta-catenin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0034452///dynactin binding+++GO:0016740///transferase activity","GO:0046777///protein autophosphorylation+++GO:0030516///regulation of axon extension+++GO:0060079///excitatory postsynaptic potential+++GO:0009968///negative regulation of signal transduction+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:1901216///positive regulation of neuron death+++GO:0005975///carbohydrate metabolic process+++GO:0048814///regulation of dendrite morphogenesis+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0030154///cell differentiation+++GO:0021766///hippocampus development+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0007212///dopamine receptor signaling pathway+++GO:0006983///ER overload response+++GO:0031333///negative regulation of protein complex assembly+++GO:0035556///intracellular signal transduction+++GO:0030010///establishment of cell polarity+++GO:1900181///negative regulation of protein localization to nucleus+++GO:0001837///epithelial to mesenchymal transition+++GO:0007399///nervous system development+++GO:0006468///protein phosphorylation+++GO:1900034///regulation of cellular response to heat+++GO:0048511///rhythmic process+++GO:0005977///glycogen metabolic process+++GO:1901984///negative regulation of protein acetylation+++GO:0032886///regulation of microtubule-based process+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0018105///peptidyl-serine phosphorylation+++GO:0036016///cellular response to interleukin-3+++GO:0010628///positive regulation of gene expression+++GO:0031175///neuron projection development+++GO:0050770///regulation of axonogenesis+++GO:2000466///negative regulation of glycogen (starch) synthase activity+++GO:0010822///positive regulation of mitochondrion organization+++GO:1904781///positive regulation of protein localization to centrosome+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0016310///phosphorylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032091///negative regulation of protein binding+++GO:0043066///negative regulation of apoptotic process+++GO:0046827///positive regulation of protein export from nucleus+++GO:1901215///negative regulation of neuron death+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0032092///positive regulation of protein binding+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0007623///circadian rhythm+++GO:0045732///positive regulation of protein catabolic process+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0071109///superior temporal gyrus development+++GO:0031334///positive regulation of protein complex assembly+++GO:1904886///beta-catenin destruction complex disassembly+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0030011///maintenance of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:1904339///negative regulation of dopaminergic neuron differentiation+++GO:1904885///beta-catenin destruction complex assembly+++GO:0106028///neuron projection retraction+++GO:2000077///negative regulation of type B pancreatic cell development+++GO:1904646///cellular response to amyloid-beta","glycogen synthase kinase 3 beta","[GSK3B_HUMAN|Reviewed]RecName: Full=Glycogen synthase kinase-3 beta; Short=GSK-3 beta; EC=2.7.11.26; AltName: Full=Serine/threonine-protein kinase GSK3B; EC=2.7.11.1;+++[B5BUC0_HUMAN|Unreviewed]SubName: Full=Glycogen synthase kinase-3 beta {ECO:0000313|EMBL:BAG70170.1}; Flags: Fragment;+++[Q6FI27_HUMAN|Unreviewed]SubName: Full=GSK3B protein {ECO:0000313|EMBL:CAG38748.1}; SubName: Full=GSK3beta isoform {ECO:0000313|EMBL:ABX89591.1}; SubName: Full=Glycogen synthase kinase 3 beta, isoform CRA_b {ECO:0000313|EMBL:EAW79534.1}; SubName: Full=cDNA FLJ75266, highly similar to Homo sapiens glycogen synthase kinase 3 beta, mRNA {ECO:0000313|EMBL:BAF83586.1};+++[Q86TM2_HUMAN|Unreviewed]SubName: Full=Glycogen synthase kinase 3 beta {ECO:0000313|EMBL:AAM88578.1}; Flags: Fragment;"]
[2967,"'GTF2H3'",234,163.27,186,194.423333333333,"03420///Nucleotide excision repair+++03022///Basal transcription factors+++05203///Viral carcinogenesis",null,"M00290///Holo-TFIIH complex",null,"GO:0097550///transcriptional preinitiation complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0000439///transcription factor TFIIH core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000438///core TFIIH complex portion of holo TFIIH complex+++GO:0005669///transcription factor TFIID complex","GO:0003684///damaged DNA binding+++GO:0005515///protein binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0047485///protein N-terminus binding+++GO:0008135///translation factor activity, RNA binding+++GO:0004672///protein kinase activity","GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0070911///global genome nucleotide-excision repair+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006412///translation+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006370///7-methylguanosine mRNA capping+++GO:0006281///DNA repair+++GO:0006289///nucleotide-excision repair+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006366///transcription by RNA polymerase II+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006355///regulation of transcription, DNA-templated+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006974///cellular response to DNA damage stimulus","general transcription factor IIH subunit 3","[TF2H3_HUMAN|Reviewed]RecName: Full=General transcription factor IIH subunit 3; AltName: Full=Basic transcription factor 2 34 kDa subunit; Short=BTF2 p34 {ECO:0000303|PubMed:8194529}; AltName: Full=General transcription factor IIH polypeptide 3; AltName: Full=TFIIH basal transcription factor complex p34 subunit {ECO:0000303|PubMed:8194529};+++[A0A087WYD5_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000481711};+++[F5GWD3_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000441894}; Flags: Fragment;+++[F5GX35_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000440482};+++[F5GXG6_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000446429}; Flags: Fragment;+++[F5H3G1_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000439121};+++[F5H4K7_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000446097}; Flags: Fragment;+++[F5H6X0_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000442977}; Flags: Fragment;+++[H0YFF7_HUMAN|Unreviewed]SubName: Full=General transcription factor IIH subunit 3 {ECO:0000313|Ensembl:ENSP00000438435}; Flags: Fragment;"]
[29760,"'BLNK'",26,41.74,41,36.2466666666667,"04064///NF-kappa B signaling pathway+++04662///B cell receptor signaling pathway+++04380///Osteoclast differentiation+++05340///Primary immunodeficiency","H00085///Agammaglobulinemias",null,null,"GO:0005737///cytoplasm+++GO:0005622///intracellular+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding+++GO:0005070///SH3/SH2 adaptor activity","GO:0035556///intracellular signal transduction+++GO:0009967///positive regulation of signal transduction+++GO:0006959///humoral immune response+++GO:0042113///B cell activation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0006954///inflammatory response+++GO:0030183///B cell differentiation","B cell linker","[BLNK_HUMAN|Reviewed]RecName: Full=B-cell linker protein; AltName: Full=B-cell adapter containing a SH2 domain protein; AltName: Full=B-cell adapter containing a Src homology 2 domain protein; AltName: Full=Cytoplasmic adapter protein; AltName: Full=Src homology 2 domain-containing leukocyte protein of 65 kDa; Short=SLP-65;+++[K7EKR2_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|Ensembl:ENSP00000465741};+++[Q2MD39_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55341.1}; Flags: Fragment;+++[Q2MD40_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55340.1}; Flags: Fragment;+++[Q2MD42_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55338.1}; Flags: Fragment;+++[Q2MD44_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55336.1}; Flags: Fragment;+++[Q2MD46_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55334.1}; Flags: Fragment;+++[Q2MD47_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55333.1, ECO:0000313|Ensembl:ENSP00000466331}; Flags: Fragment;+++[Q2MD48_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55332.1}; Flags: Fragment;+++[Q2MD50_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55330.1}; Flags: Fragment;+++[Q2MD51_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55329.1}; Flags: Fragment;+++[Q2MD52_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55328.1}; Flags: Fragment;+++[Q2MD54_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55326.1}; Flags: Fragment;+++[Q2MD55_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55325.1}; Flags: Fragment;+++[Q2MD56_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55324.1}; Flags: Fragment;+++[Q2MD57_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55323.1}; Flags: Fragment;+++[Q2MD58_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55322.1}; Flags: Fragment;+++[Q2MD59_HUMAN|Unreviewed]SubName: Full=B-cell linker protein {ECO:0000313|EMBL:CAJ55321.1, ECO:0000313|Ensembl:ENSP00000391924}; Flags: Fragment;"]
[29841,"'GRHL1'",16,25,18,19.6666666666667,null,"H00604///Deafness, autosomal dominant+++H01927///Van der Woude syndrome",null,null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0031490///chromatin DNA binding+++GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0002934///desmosome organization+++GO:0061436///establishment of skin barrier+++GO:0045616///regulation of keratinocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019216///regulation of lipid metabolic process+++GO:0008544///epidermis development+++GO:0007275///multicellular organism development","grainyhead like transcription factor 1","[GRHL1_HUMAN|Reviewed]RecName: Full=Grainyhead-like protein 1 homolog {ECO:0000312|HGNC:HGNC:17923}; AltName: Full=Mammalian grainyhead; AltName: Full=NH32; AltName: Full=Transcription factor CP2-like 2; AltName: Full=Transcription factor LBP-32;+++[B7Z1S6_HUMAN|Unreviewed]SubName: Full=Grainyhead-like protein 1 homolog {ECO:0000313|Ensembl:ENSP00000420654}; SubName: Full=cDNA FLJ51493, highly similar to Grainyhead-like protein 1 {ECO:0000313|EMBL:BAH11612.1};+++[C9JYY8_HUMAN|Unreviewed]SubName: Full=Grainyhead-like protein 1 homolog {ECO:0000313|Ensembl:ENSP00000419831};+++[F8WFB0_HUMAN|Unreviewed]SubName: Full=Grainyhead-like protein 1 homolog {ECO:0000313|Ensembl:ENSP00000387521};"]
[29882,"'ANAPC2'",738,810,826,791.333333333333,"04110///Cell cycle+++04111///Cell cycle - yeast+++04114///Oocyte meiosis+++04120///Ubiquitin mediated proteolysis+++05166///HTLV-I infection+++04914///Progesterone-mediated oocyte maturation+++04113///Meiosis - yeast",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005680///anaphase-promoting complex+++GO:0005829///cytosol","GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0070979///protein K11-linked ubiquitination+++GO:0090129///positive regulation of synapse maturation+++GO:0045773///positive regulation of axon extension+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0031915///positive regulation of synaptic plasticity+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0051301///cell division+++GO:0030154///cell differentiation+++GO:0007049///cell cycle+++GO:0007399///nervous system development","anaphase promoting complex subunit 2","[ANC2_HUMAN|Reviewed]RecName: Full=Anaphase-promoting complex subunit 2; Short=APC2; AltName: Full=Cyclosome subunit 2;"]
[29895,"'MYLPF'",15,12,12,13,"04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0005765///lysosomal membrane+++GO:0016459///myosin complex+++GO:0005859///muscle myosin complex+++GO:0005829///cytosol","GO:0005509///calcium ion binding+++GO:0008307///structural constituent of muscle+++GO:0046872///metal ion binding","GO:0006955///immune response+++GO:0006936///muscle contraction+++GO:0007519///skeletal muscle tissue development","myosin light chain, phosphorylatable, fast skeletal muscle","[MLRS_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 2, skeletal muscle isoform; AltName: Full=Fast skeletal myosin light chain 2; AltName: Full=MLC2B;+++[A0A024QZG6_HUMAN|Unreviewed]SubName: Full=Fast skeletal myosin light chain 2, isoform CRA_a {ECO:0000313|EMBL:EAW52255.1};+++[H3BML9_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 2, skeletal muscle isoform {ECO:0000313|Ensembl:ENSP00000454444}; Flags: Fragment;+++[H3BN54_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 2, skeletal muscle isoform {ECO:0000313|Ensembl:ENSP00000454694}; Flags: Fragment;+++[H3BPK4_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 2, skeletal muscle isoform {ECO:0000313|Ensembl:ENSP00000455356}; Flags: Fragment;"]
[29929,"'ALG6'",74,43,93,70,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis","H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R06262///dolichyl beta-D-glucosyl phosphate:D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase   Dolichyl D-glucosyl phosphate + G00007 <=> Dolichyl phosphate + G10598","GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0042281///dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0046527///glucosyltransferase activity+++GO:0004583///dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006487///protein N-linked glycosylation","ALG6, alpha-1,3-glucosyltransferase","[ALG6_HUMAN|Reviewed]RecName: Full=Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; EC=2.4.1.267; AltName: Full=Asparagine-linked glycosylation protein 6 homolog; AltName: Full=Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase; AltName: Full=Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase;+++[A2A2G4_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110};+++[R4GMS5_HUMAN|Unreviewed]SubName: Full=Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase {ECO:0000313|Ensembl:ENSP00000473328};+++[S4R350_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110};"]
[29942,"'PURG'",9,7,7,7.66666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0032422///purine-rich negative regulatory element binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II","purine rich element binding protein G","[PURG_HUMAN|Reviewed]RecName: Full=Purine-rich element-binding protein gamma; Short=Purine-rich element-binding protein G;+++[K7ENC1_HUMAN|Unreviewed]SubName: Full=Purine-rich element-binding protein gamma {ECO:0000313|Ensembl:ENSP00000466881}; Flags: Fragment;+++[L8E8I6_HUMAN|Unreviewed]SubName: Full=Alternative protein PURG {ECO:0000313|EMBL:CCQ43041.1};"]
[29959,"'NRBP1'",2287,2542,2282,2370.33333333333,{"$nulls":4},"GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005654///nucleoplasm+++GO:0030027///lamellipodium","GO:0042803///protein homodimerization activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006367///transcription initiation from RNA polymerase II promoter","nuclear receptor binding protein 1","[NRBP_HUMAN|Reviewed]RecName: Full=Nuclear receptor-binding protein;+++[C9JDW7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-binding protein {ECO:0000313|Ensembl:ENSP00000415406}; Flags: Fragment;+++[C9JHZ6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-binding protein {ECO:0000313|Ensembl:ENSP00000403916}; Flags: Fragment;+++[F8W6G1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-binding protein {ECO:0000313|Ensembl:ENSP00000369192};"]
[3000,"'GUCY2D'",4,6,11,7,"04744///Phototransduction+++00230///Purine metabolism+++04740///Olfactory transduction","H00837///Leber congenital amaurosis (LCR)+++H00481///Cone-rod dystrophy and cone dystrophy+++H01768///Central areolar choroidal dystrophy",null,"R00434///GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)   GTP <=> 3',5'-Cyclic GMP + Diphosphate","GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005640///nuclear outer membrane+++GO:0097381///photoreceptor disc membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016829///lyase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004383///guanylate cyclase activity+++GO:0001653///peptide receptor activity+++GO:0005525///GTP binding+++GO:0038023///signaling receptor activity+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity","GO:0006182///cGMP biosynthetic process+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0050896///response to stimulus+++GO:0007165///signal transduction+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0007601///visual perception","guanylate cyclase 2D, retinal","[GUC2D_HUMAN|Reviewed]RecName: Full=Retinal guanylyl cyclase 1; Short=RETGC-1; EC=4.6.1.2; AltName: Full=Guanylate cyclase 2D, retinal; AltName: Full=Rod outer segment membrane guanylate cyclase; Short=ROS-GC; Flags: Precursor;"]
[30011,"'SH3KBP1'",1572,1441,1673,1562,"04144///Endocytosis",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005911///cell-cell junction+++GO:0005856///cytoskeleton+++GO:0045202///synapse+++GO:0005886///plasma membrane+++GO:0043005///neuron projection+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005925///focal adhesion+++GO:0030139///endocytic vesicle+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding+++GO:0017124///SH3 domain binding","GO:0007010///cytoskeleton organization+++GO:0006897///endocytosis+++GO:0007267///cell-cell signaling+++GO:0007411///axon guidance+++GO:0008360///regulation of cell shape+++GO:0006915///apoptotic process+++GO:0061024///membrane organization+++GO:0016477///cell migration+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway","SH3 domain containing kinase binding protein 1","[SH3K1_HUMAN|Reviewed]RecName: Full=SH3 domain-containing kinase-binding protein 1; AltName: Full=CD2-binding protein 3; Short=CD2BP3; AltName: Full=Cbl-interacting protein of 85 kDa; AltName: Full=Human Src family kinase-binding protein 1; Short=HSB-1;+++[B7Z6E8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59425, highly similar to SH3-domain kinase-binding protein 1 {ECO:0000313|EMBL:BAH13234.1};+++[L0R6P6_HUMAN|Unreviewed]SubName: Full=Alternative protein SH3KBP1 {ECO:0000313|EMBL:CCO13812.1};+++[Q5JPT1_HUMAN|Unreviewed]SubName: Full=SH3 domain-containing kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000388766}; Flags: Fragment;+++[Q5JPT2_HUMAN|Unreviewed]SubName: Full=SH3 domain-containing kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000369049}; Flags: Fragment;+++[Q5JPT3_HUMAN|Unreviewed]SubName: Full=SH3 domain-containing kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000409292}; Flags: Fragment;+++[Q5JPT6_HUMAN|Unreviewed]SubName: Full=GIG10 {ECO:0000313|EMBL:AAT08174.1}; SubName: Full=Migration-inducing gene 18 protein {ECO:0000313|EMBL:AAS00497.1}; SubName: Full=cDNA, FLJ93821, Homo sapiens SH3-domain kinase binding protein 1 (SH3KBP1), mRNA {ECO:0000313|EMBL:BAG36113.1};+++[Q5VSN0_HUMAN|Unreviewed]SubName: Full=SH3 domain-containing kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000369019};"]
[3050,"'HBZ'",14,13,17,14.6666666666667,{"$nulls":4},"GO:0005833///hemoglobin complex+++GO:0070062///extracellular exosome+++GO:0031838///haptoglobin-hemoglobin complex","GO:0004601///peroxidase activity+++GO:0005344///oxygen carrier activity+++GO:0019825///oxygen binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0043177///organic acid binding+++GO:0031720///haptoglobin binding+++GO:0020037///heme binding","GO:0043249///erythrocyte maturation+++GO:0042744///hydrogen peroxide catabolic process+++GO:0051291///protein heterooligomerization+++GO:0098869///cellular oxidant detoxification+++GO:0015671///oxygen transport+++GO:0000122///negative regulation of transcription by RNA polymerase II","hemoglobin subunit zeta","[HBAZ_HUMAN|Reviewed]RecName: Full=Hemoglobin subunit zeta; AltName: Full=HBAZ; AltName: Full=Hemoglobin zeta chain; AltName: Full=Zeta-globin;+++[Q1W6G9_HUMAN|Unreviewed]SubName: Full=Hemoglobin zeta subunit {ECO:0000313|EMBL:ABD95908.1};"]
[3059,"'HCLS1'",3,1,2,2,"05205///Proteoglycans in cancer+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++04530///Tight junction+++05131///Shigellosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005667///transcription factor complex+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0019901///protein kinase binding+++GO:0017124///SH3 domain binding+++GO:0044877///protein-containing complex binding+++GO:0001085///RNA polymerase II transcription factor binding","GO:0030218///erythrocyte differentiation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0035556///intracellular signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0071345///cellular response to cytokine stimulus+++GO:2000107///negative regulation of leukocyte apoptotic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0009725///response to hormone+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0030833///regulation of actin filament polymerization+++GO:0045651///positive regulation of macrophage differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0042307///positive regulation of protein import into nucleus+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030041///actin filament polymerization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II","hematopoietic cell-specific Lyn substrate 1","[HCLS1_HUMAN|Reviewed]RecName: Full=Hematopoietic lineage cell-specific protein; AltName: Full=Hematopoietic cell-specific LYN substrate 1; AltName: Full=LckBP1; AltName: Full=p75;+++[E7EVW7_HUMAN|Unreviewed]SubName: Full=Hematopoietic lineage cell-specific protein {ECO:0000313|Ensembl:ENSP00000387645};+++[F8WDD5_HUMAN|Unreviewed]SubName: Full=Hematopoietic lineage cell-specific protein {ECO:0000313|Ensembl:ENSP00000420507};+++[F8WEZ6_HUMAN|Unreviewed]SubName: Full=Hematopoietic lineage cell-specific protein {ECO:0000313|Ensembl:ENSP00000419614};"]
[3074,"'HEXB'",3630,3741,3211,3527.33333333333,"01100///Metabolic pathways+++00513///Various types of N-glycan biosynthesis+++00531///Glycosaminoglycan degradation+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++04142///Lysosome+++00520///Amino sugar and nucleotide sugar metabolism+++00604///Glycosphingolipid biosynthesis - ganglio series+++00511///Other glycan degradation","H00124///GM2 gangliosidoses+++H02016///Tay-Sachs disease+++H00426///Defects in the degradation of ganglioside+++H02017///Sandhoff disease","M00079///Keratan sulfate degradation","R06004///GM2 + H2O <=> GM3 + N-Acetyl-D-galactosamine+++R11316///G13056 + H2O <=> N-Acetyl-D-glucosamine + G10665+++R00022///chitobiose N-acetylglucosaminohydrolase   Chitobiose + H2O <=> 2 N-Acetyl-D-glucosamine","GO:0001669///acrosomal vesicle+++GO:0005764///lysosome+++GO:0043202///lysosomal lumen+++GO:0042582///azurophil granule+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0035578///azurophil granule lumen+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0046982///protein heterodimerization activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0042803///protein homodimerization activity+++GO:0004563///beta-N-acetylhexosaminidase activity+++GO:0016787///hydrolase activity+++GO:0102148///N-acetyl-beta-D-galactosaminidase activity","GO:0042552///myelination+++GO:0007040///lysosome organization+++GO:0005975///carbohydrate metabolic process+++GO:0030207///chondroitin sulfate catabolic process+++GO:0007341///penetration of zona pellucida+++GO:0007338///single fertilization+++GO:0007605///sensory perception of sound+++GO:0050905///neuromuscular process+++GO:0006874///cellular calcium ion homeostasis+++GO:0042340///keratan sulfate catabolic process+++GO:0048477///oogenesis+++GO:0043312///neutrophil degranulation+++GO:0006687///glycosphingolipid metabolic process+++GO:0030214///hyaluronan catabolic process+++GO:0006689///ganglioside catabolic process+++GO:0007626///locomotory behavior+++GO:0008654///phospholipid biosynthetic process+++GO:0050885///neuromuscular process controlling balance+++GO:0008152///metabolic process+++GO:0008360///regulation of cell shape+++GO:0031323///regulation of cellular metabolic process+++GO:0008049///male courtship behavior+++GO:0030203///glycosaminoglycan metabolic process+++GO:0019953///sexual reproduction+++GO:0043615///astrocyte cell migration+++GO:0019915///lipid storage+++GO:0001501///skeletal system development+++GO:0044267///cellular protein metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0009313///oligosaccharide catabolic process","hexosaminidase subunit beta","[HEXB_HUMAN|Reviewed]RecName: Full=Beta-hexosaminidase subunit beta; EC=3.2.1.52; AltName: Full=Beta-N-acetylhexosaminidase subunit beta; Short=Hexosaminidase subunit B; AltName: Full=Cervical cancer proto-oncogene 7 protein; Short=HCC-7; AltName: Full=N-acetyl-beta-glucosaminidase subunit beta; Contains: RecName: Full=Beta-hexosaminidase subunit beta chain B; Contains: RecName: Full=Beta-hexosaminidase subunit beta chain A; Flags: Precursor;+++[A0A024RAJ6_HUMAN|Unreviewed]RecName: Full=Beta-hexosaminidase {ECO:0000256|PIRNR:PIRNR001093}; EC=3.2.1.52 {ECO:0000256|PIRNR:PIRNR001093};+++[D6REQ8_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000424939};+++[H0Y9B6_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000423713}; Flags: Fragment;+++[H0Y9M3_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000424550}; Flags: Fragment;+++[H0YA83_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000426384}; Flags: Fragment;+++[Q5URX0_HUMAN|Unreviewed]SubName: Full=Beta-hexosaminidase subunit beta {ECO:0000313|Ensembl:ENSP00000426285}; SubName: Full=ENC-1AS {ECO:0000313|EMBL:AAV48875.1}; SubName: Full=Epididymis luminal protein 248 {ECO:0000313|EMBL:ACI46028.1}; SubName: Full=Epididymis secretory protein Li 111 {ECO:0000313|EMBL:ACV87197.1};"]
[30835,"'CD209'",0,1,0,0.333333333333333,"04145///Phagosome+++05162///Measles+++05152///Tuberculosis+++04625///C-type lectin receptor signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0009897///external side of plasma membrane+++GO:0005886///plasma membrane+++GO:0043657///host cell+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0042605///peptide antigen binding+++GO:0001618///virus receptor activity+++GO:0005537///mannose binding+++GO:0046872///metal ion binding+++GO:0030246///carbohydrate binding+++GO:0046790///virion binding+++GO:0005515///protein binding","GO:0002250///adaptive immune response+++GO:0035556///intracellular signal transduction+++GO:0007159///leukocyte cell-cell adhesion+++GO:0075733///intracellular transport of virus+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0006897///endocytosis+++GO:0007155///cell adhesion+++GO:0046968///peptide antigen transport+++GO:0019882///antigen processing and presentation+++GO:0042129///regulation of T cell proliferation+++GO:0045087///innate immune response+++GO:0097323///B cell adhesion+++GO:0019062///virion attachment to host cell+++GO:0046718///viral entry into host cell+++GO:0042102///positive regulation of T cell proliferation+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0016032///viral process+++GO:0019079///viral genome replication+++GO:0009988///cell-cell recognition+++GO:0002376///immune system process+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","CD209 molecule","[CD209_HUMAN|Reviewed]RecName: Full=CD209 antigen; AltName: Full=C-type lectin domain family 4 member L; AltName: Full=Dendritic cell-specific ICAM-3-grabbing non-integrin 1; Short=DC-SIGN; Short=DC-SIGN1; AltName: CD_antigen=CD209;+++[B2R907_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94149, highly similar to Homo sapiens CD209 antigen (CD209), mRNA {ECO:0000313|EMBL:BAG36354.1};+++[B4E2A8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61677, highly similar to CD209 antigen {ECO:0000313|EMBL:BAG65070.1};+++[M0QZG5_HUMAN|Unreviewed]SubName: Full=CD209 antigen, isoform CRA_j {ECO:0000313|EMBL:EAW69000.1};+++[M0R0P0_HUMAN|Unreviewed]SubName: Full=CD209 antigen, isoform CRA_b {ECO:0000313|EMBL:EAW68992.1};+++[X6RB12_HUMAN|Unreviewed]SubName: Full=CD209 antigen {ECO:0000313|Ensembl:ENSP00000377728};"]
[3092,"'HIP1'",434,307.99,344,361.996666666667,"05016///Huntington's disease",{"$nulls":3},"GO:0030122///AP-2 adaptor complex+++GO:0016020///membrane+++GO:0030479///actin cortical patch+++GO:0005794///Golgi apparatus+++GO:0030665///clathrin-coated vesicle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0005634///nucleus+++GO:0098888///extrinsic component of presynaptic membrane+++GO:0005737///cytoplasm+++GO:0098793///presynapse+++GO:0098794///postsynapse+++GO:0031410///cytoplasmic vesicle+++GO:0005856///cytoskeleton+++GO:0030136///clathrin-coated vesicle+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0045211///postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane","GO:0003779///actin binding+++GO:0035091///phosphatidylinositol binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0035615///clathrin adaptor activity+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0032051///clathrin light chain binding+++GO:0035254///glutamate receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0005543///phospholipid binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0051015///actin filament binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0030276///clathrin binding","GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0042981///regulation of apoptotic process+++GO:0072583///clathrin-dependent endocytosis+++GO:0006915///apoptotic process+++GO:0097190///apoptotic signaling pathway+++GO:2000588///positive regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0099637///neurotransmitter receptor transport+++GO:0030154///cell differentiation+++GO:0030100///regulation of endocytosis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0050821///protein stabilization+++GO:0048268///clathrin coat assembly+++GO:0061024///membrane organization+++GO:0007015///actin filament organization+++GO:0006897///endocytosis+++GO:0051897///positive regulation of protein kinase B signaling","huntingtin interacting protein 1","[HIP1_HUMAN|Reviewed]RecName: Full=Huntingtin-interacting protein 1; Short=HIP-1; AltName: Full=Huntingtin-interacting protein I; Short=HIP-I;+++[A0A0A6ZH24_HUMAN|Unreviewed]SubName: Full=HCG1795174 {ECO:0000313|EMBL:EAW71769.1}; SubName: Full=SHONbeta {ECO:0000313|EMBL:AGS49178.1};+++[A0A0A6ZH34_HUMAN|Unreviewed]SubName: Full=SHONgamma {ECO:0000313|EMBL:AGS49179.1};+++[A4VCI6_HUMAN|Unreviewed]SubName: Full=HIP1 protein {ECO:0000313|EMBL:AAI39787.1}; Flags: Fragment;+++[B4DK46_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56785, highly similar to Huntingtin-interacting protein 1 {ECO:0000313|EMBL:BAG59058.1};+++[C9JMG5_HUMAN|Unreviewed]SubName: Full=Huntingtin-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000414280}; Flags: Fragment;+++[Q6UY29_HUMAN|Unreviewed]SubName: Full=PIKR2786 {ECO:0000313|EMBL:AAQ88470.1}; SubName: Full=SHONalpha {ECO:0000313|EMBL:AGS49177.1};+++[Q8TDA4_HUMAN|Unreviewed]SubName: Full=Huntingtin-interacting protein 1 {ECO:0000313|EMBL:AAL93198.1}; Flags: Fragment;"]
[{"$cut":{"chars":32759,"head":"bName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT40990.1}; Flags: Fragment;+++[A0A2I4PZL9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41000.1}; Flags: Fragment;+++[A0A2I4PZM6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT40999.1}; Flags: Fragment;+++[A0A2I4PZM7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41010.1}; Flags: Fragment;+++[A0A2I4PZN6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41020.1}; Flags: Fragment;+++[A0A2I4PZN8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41009.1}; Flags: Fragment;+++[A0A2I4PZP4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41030.1}; Flags: Fragment;+++[A0A2I4PZP7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41019.1}; Flags: Fragment;+++[A0A2I4PZQ3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41040.1}; Flags: Fragment;+++[A0A2I4PZR2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41029.1}; Flags: Fragment;+++[A0A2I4PZS0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41050.1}; Flags: Fragment;+++[A0A2I4PZS7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41039.1}; Flags: Fragment;+++[A0A2I4PZT0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41060.1}; Flags: Fragment;+++[A0A2I4PZT9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41049.1}; Flags: Fragment;+++[A0A2I4PZV1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AQT41059.1}; Flags: Fragment;+++[A0A2I6J488_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81567.1};+++[A0A2I6J489_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81568.1};+++[A0A2I6J4A5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81566.1};+++[A0A2I6J4A6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81571.1};+++[A0A2I6J4A7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81577.1};+++[A0A2I6J4B0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81570.1};+++[A0A2I6J4B1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81581.1};+++[A0A2I6J4B5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81569.1};+++[A0A2I6J4B6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81580.1};+++[A0A2I6J4C1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81579.1};+++[A0A2I6J4C3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81596.1};+++[A0A2I6J4C7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81600.1};+++[A0A2I6J4D2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81573.1};+++[A0A2I6J4D3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81574.1};+++[A0A2I6J4D4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81572.1};+++[A0A2I6J4D9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81584.1};+++[A0A2I6J4E1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81595.1};+++[A0A2I6J4E2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81594.1};+++[A0A2I6J4E5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUL81605.1};+++[A0A2I6SQU3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AUO28753.1};+++[A0A2K4N7U6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:SBV08723.1};+++[A0A2K4N814_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:SCL43736.1};+++[A0A2K4N817_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:SCL43737.1};+++[A0A2K4N833_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:SCL43730.1};+++[A0A2K4N851_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:SCL43748.1};+++[A0A2K4N853_HUMAN|Unreviewed]Sub"}}]
[{"$cut":{"chars":32759,"head":"me: Full=MHC class I antigen {ECO:0000313|EMBL:BAE95333.1}; Flags: Fragment;+++[Q1G4P0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF58776.1}; Flags: Fragment;+++[Q1G4P1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF58775.1}; Flags: Fragment;+++[Q1G4P2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF58774.1}; Flags: Fragment;+++[Q1G4P3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF58773.1}; Flags: Fragment;+++[Q1HHB9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF29706.1}; Flags: Fragment;+++[Q1HHC0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF47209.1}; Flags: Fragment;+++[Q1KLJ7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF18978.1}; Flags: Fragment;+++[Q1KLJ8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABF18977.1}; Flags: Fragment;+++[Q1M2R8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:CAK02800.1}; Flags: Fragment;+++[Q1PBJ8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABE27974.1}; Flags: Fragment;+++[Q1PBJ9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABE27973.1}; Flags: Fragment;+++[Q1W4D6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD98442.1}; Flags: Fragment;+++[Q1W5T2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD93917.1}; Flags: Fragment;+++[Q1W5T3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD93916.1}; Flags: Fragment;+++[Q1W5T6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD93913.1}; Flags: Fragment;+++[Q1WAA8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABE00937.1}; Flags: Fragment;+++[Q1WAB1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABE00934.1}; Flags: Fragment;+++[Q1XG28_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:BAE93145.1};+++[Q206J8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD75334.1}; Flags: Fragment;+++[Q206J9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD75333.1}; Flags: Fragment;+++[Q208P6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD64774.1}; Flags: Fragment;+++[Q25B79_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:CAG24006.1}; Flags: Fragment;+++[Q25BN7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:BAE87033.1}; Flags: Fragment;+++[Q27I50_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD62878.1}; Flags: Fragment;+++[Q27I52_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD62876.1}; Flags: Fragment;+++[Q27I55_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD62873.1}; Flags: Fragment;+++[Q27I56_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD62872.1}; Flags: Fragment;+++[Q27I57_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ABD62871.1}; Flags: Fragment;+++[Q29634_HUMAN|Unreviewed]SubName: Full=MHC class I antigen R69772 {ECO:0000313|EMBL:AAB01213.1}; Flags: Fragment;+++[Q29689_HUMAN|Unreviewed]SubName: Full=MHC class I antigen HLA-A2407 {ECO:0000313|EMBL:AAA73518.1};+++[Q29724_HUMAN|Unreviewed]SubName: Full=MHC class I antigen HLA-A {ECO:0000313|EMBL:AAA80238.1}; Flags: Fragment;+++[Q29739_HUMAN|Unreviewed]SubName: Full=MHC class I antigen HLA-A {ECO:0000313|EMBL:AAA87570.1}; Flags: Fragment;+++[Q29740_HUMAN|Unreviewed]SubName: Full=MHC class I antigen HLA-A {ECO:0000313|EMBL:AAA87571.1}; Flags: Fragment;+++[Q29741_HUMAN|Unreviewed]SubName: Full=MHC class I antigen HLA-A {ECO:0000313|EMBL:AAA87572.1}; Flags: Fragment;+++[Q29756_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AAB59614.2}; Flags: Fragment;+++[Q29757_HUMAN|Unreviewed]SubName: Full=HLA-A protein {ECO:0000313|EMBL:BAA07530.1}; SubName: Full=MHC class I antigen {ECO:0000313|EMBL:BAW27645.1};+++[Q29840_HUMAN|Unreviewed]SubName: Full=MHC c"}}]
["++[D3U470_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ACN81226.1}; Flags: Fragment;+++[D3U471_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ACN81227.1}; Flags: Fragment;+++[D3U487_HUMAN|Unreviewed]SubName: F"]
[{"$cut":{"chars":19753,"head":"Name: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90570.1}; Flags: Fragment;+++[V5NPQ5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90575.1}; Flags: Fragment;+++[V5NPR0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90580.1}; Flags: Fragment;+++[V5NQ37_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90536.1}; Flags: Fragment;+++[V5NQ42_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90541.1}; Flags: Fragment;+++[V5NQ48_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90546.1}; Flags: Fragment;+++[V5NQ52_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90551.1}; Flags: Fragment;+++[V5NQ55_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90534.1}; Flags: Fragment;+++[V5NQ58_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90556.1}; Flags: Fragment;+++[V5NQ60_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90539.1}; Flags: Fragment;+++[V5NQ62_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90561.1}; Flags: Fragment;+++[V5NQ66_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90544.1}; Flags: Fragment;+++[V5NQ69_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90566.1}; Flags: Fragment;+++[V5NQ72_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90549.1}; Flags: Fragment;+++[V5NQ74_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90571.1}; Flags: Fragment;+++[V5NQ78_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90554.1}; Flags: Fragment;+++[V5NQ80_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90576.1}; Flags: Fragment;+++[V5NQ84_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90559.1}; Flags: Fragment;+++[V5NQ85_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90581.1}; Flags: Fragment;+++[V5NQ91_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90564.1}; Flags: Fragment;+++[V5NQ95_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90569.1}; Flags: Fragment;+++[V5NQA3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90574.1}; Flags: Fragment;+++[V5NQA8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90579.1}; Flags: Fragment;+++[V5NQB4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90584.1}; Flags: Fragment;+++[V5NQP8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90538.1}; Flags: Fragment;+++[V5NQQ2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90543.1}; Flags: Fragment;+++[V5NQQ7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90548.1}; Flags: Fragment;+++[V5NQR2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90553.1}; Flags: Fragment;+++[V5NQR8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90558.1}; Flags: Fragment;+++[V5NQS4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90563.1}; Flags: Fragment;+++[V5NQS8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90568.1}; Flags: Fragment;+++[V5NQT4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90573.1}; Flags: Fragment;+++[V5NQT9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90578.1}; Flags: Fragment;+++[V5NQU5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90583.1}; Flags: Fragment;+++[V5NS56_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90537.1}; Flags: Fragment;+++[V5NS61_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90542.1}; Flags: Fragment;+++[V5NS67_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90547.1}; Flags: Fragment;+++[V5NS72_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHA90552.1}; F"}}]
[{"$cut":{"chars":32759,"head":"BL:ADZ05540.1}; Flags: Fragment;+++[F1CCI5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05541.1}; Flags: Fragment;+++[F1CCI6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05542.1}; Flags: Fragment;+++[F1CCI7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05543.1}; Flags: Fragment;+++[F1CCI8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05544.1}; Flags: Fragment;+++[F1CCI9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05545.1}; Flags: Fragment;+++[F1CCJ0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05546.1}; Flags: Fragment;+++[F1CCJ1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05547.1}; Flags: Fragment;+++[F1CCJ2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05548.1}; Flags: Fragment;+++[F1CCJ3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05549.1}; Flags: Fragment;+++[F1CCJ4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05550.1}; Flags: Fragment;+++[F1CCJ5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05551.1}; Flags: Fragment;+++[F1CCJ6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05552.1}; Flags: Fragment;+++[F1CCJ7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05553.1}; Flags: Fragment;+++[F1CCJ8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05554.1}; Flags: Fragment;+++[F1CCJ9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05555.1}; Flags: Fragment;+++[F1CCK0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05556.1}; Flags: Fragment;+++[F1CCK1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05557.1}; Flags: Fragment;+++[F1CCK2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05558.1}; Flags: Fragment;+++[F1CCK3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05559.1}; Flags: Fragment;+++[F1CCK4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05560.1}; Flags: Fragment;+++[F1CCK5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05561.1}; Flags: Fragment;+++[F1CCK6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05562.1}; Flags: Fragment;+++[F1CCK7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05563.1}; Flags: Fragment;+++[F1CCK8_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05564.1}; Flags: Fragment;+++[F1CCK9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05565.1}; Flags: Fragment;+++[F1CCL0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05566.1}; Flags: Fragment;+++[F1CCL1_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05567.1}; Flags: Fragment;+++[F1CCL2_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05568.1}; Flags: Fragment;+++[F1CCL3_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05569.1}; Flags: Fragment;+++[F1CCL4_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05570.1}; Flags: Fragment;+++[F1CCL5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05571.1}; Flags: Fragment;+++[F1CCL6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ05572.1}; Flags: Fragment;+++[F1CK28_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADX97429.1}; Flags: Fragment;+++[F1CK31_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADX97432.1}; Flags: Fragment;+++[F1CZ00_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADX31870.1};+++[F2QL94_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:CCA30660.1}; Flags: Fragment;+++[F2VNN9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADE58697.1}; Flags: Fragment;+++[F2VNP0_HUMAN|Unreviewed]SubName: Full=MHC cl"}}]
[3119,"'HLA-DQB1'",37,28,20,28.3333333333333,"05310///Asthma+++04145///Phagosome+++05330///Allograft rejection+++04658///Th1 and Th2 cell differentiation+++05323///Rheumatoid arthritis+++05152///Tuberculosis+++05321///Inflammatory bowel disease (IBD)+++05168///Herpes simplex infection+++04612///Antigen processing and presentation+++05150///Staphylococcus aureus infection+++05140///Leishmaniasis+++05332///Graft-versus-host disease+++05416///Viral myocarditis+++04672///Intestinal immune network for IgA production+++05166///HTLV-I infection+++05320///Autoimmune thyroid disease+++05164///Influenza A+++04640///Hematopoietic cell lineage+++04940///Type I diabetes mellitus+++05145///Toxoplasmosis+++04514///Cell adhesion molecules (CAMs)+++05322///Systemic lupus erythematosus+++04659///Th17 cell differentiation","H00079///Asthma+++H01492///Systemic sclerosis+++H00295///Viral myocarditis+++H00083///Allograft rejection+++H00294///Dilated cardiomyopathy (DCM)+++H01516///Adult onset Still's disease+++H01698///Giant cell arteritis+++H00342///Tuberculosis+++H01504///Vogt-Koyanagi-Harada syndrome+++H00408///Type I diabetes mellitus+++H02123///Celiac disease+++H00081///Hashimoto's thyroiditis+++H00080///Systemic lupus erythematosus+++H01362///Dermatitis herpetiformis+++H01502///Sjogren's syndrome+++H00082///Graves' disease+++H01468///Eosinophilic granulomatosis with polyangiitis+++H01490///Multiple sclerosis",null,null,"GO:0030669///clathrin-coated endocytic vesicle membrane+++GO:0030658///transport vesicle membrane+++GO:0042613///MHC class II protein complex+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0010008///endosome membrane+++GO:0030666///endocytic vesicle membrane+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005765///lysosomal membrane+++GO:0000139///Golgi membrane","GO:0042605///peptide antigen binding+++GO:0032395///MHC class II receptor activity","GO:0006955///immune response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0002455///humoral immune response mediated by circulating immunoglobulin+++GO:0050852///T cell receptor signaling pathway+++GO:0002381///immunoglobulin production involved in immunoglobulin mediated immune response+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","major histocompatibility complex, class II, DQ beta 1","[DQB1_HUMAN|Reviewed]RecName: Full=HLA class II histocompatibility antigen, DQ beta 1 chain; AltName: Full=MHC class II antigen DQB1; Flags: Precursor;+++[F1DKR0_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:ADX99572.1}; Flags: Fragment;+++[F2XI63_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ38973.1}; Flags: Fragment;+++[F2XI64_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ38974.1}; Flags: Fragment;+++[F2XI65_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ38975.1}; Flags: Fragment;+++[F2XI66_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ38976.1}; Flags: Fragment;+++[F2XI67_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ38977.1}; Flags: Fragment;+++[F2XI68_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADZ38978.1}; Flags: Fragment;+++[H9BWE7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AFD97749.1}; Flags: Fragment;+++[O19506_HUMAN|Unreviewed]SubName: Full=MHC class II HLA-DQB1 {ECO:0000313|EMBL:AAB86436.1}; Flags: Fragment;+++[Q5SU54_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DQ beta 1 chain {ECO:0000313|Ensembl:ENSP00000364080}; SubName: Full=MHC class II antigen {ECO:0000313|EMBL:CRL52706.1};+++[Q5Y7A9_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAU88036.1}; SubName: Full=cDNA FLJ52646, highly similar to HLA class II histocompatibility antigen, DQB1*0602 beta chain {ECO:0000313|EMBL:BAG59223.1};+++[Q5Y7D3_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DQ beta 1 chain {ECO:0000313|Ensembl:ENSP00000372602}; SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAU88012.1};+++[Q5Y7D6_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DQ beta 1 chain {ECO:0000313|Ensembl:ENSP00000382034}; SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAU88009.1}; SubName: Full=cDNA, FLJ79232, highly similar to HLA class II histocompatibility antigen, DQB1*0602 beta chain {ECO:0000313|EMBL:BAH14704.1};+++[T2D2V0_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AGV40759.1}; Flags: Fragment;+++[T2D3H4_HUMAN|Unreviewed]SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AGV40760.1}; Flags: Fragment;"]
[3133,"'HLA-E'",2765,2733.28,2617.99,2705.42333333333,"05169///Epstein-Barr virus infection+++04144///Endocytosis+++05330///Allograft rejection+++05203///Viral carcinogenesis+++04940///Type I diabetes mellitus+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05165///Human papillomavirus infection+++04612///Antigen processing and presentation+++05332///Graft-versus-host disease+++05163///Human cytomegalovirus infection+++05320///Autoimmune thyroid disease+++05168///Herpes simplex infection+++04145///Phagosome+++04514///Cell adhesion molecules (CAMs)+++05416///Viral myocarditis+++04218///Cellular senescence+++05166///HTLV-I infection","H01674///Ankylosing spondylitis+++H01476///Behcet disease+++H01507///Seronegative arthritis (SpA)+++H00344///Leprosy+++H01713///Diffuse panbronchiolitis+++H01694///Stevens-Johnson syndrome and toxic epidermal necrolysis",null,null,"GO:0031901///early endosome membrane+++GO:0042612///MHC class I protein complex+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0032398///MHC class Ib protein complex+++GO:0030670///phagocytic vesicle membrane+++GO:0070062///extracellular exosome+++GO:0055038///recycling endosome membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface","GO:0005102///signaling receptor binding+++GO:0030881///beta-2-microglobulin binding+++GO:0042608///T cell receptor binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0042288///MHC class I protein binding+++GO:0005515///protein binding+++GO:0042605///peptide antigen binding","GO:0036037///CD8-positive, alpha-beta T cell activation+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:2000566///positive regulation of CD8-positive, alpha-beta T cell proliferation+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:2001187///positive regulation of CD8-positive, alpha-beta T cell activation+++GO:0002376///immune system process+++GO:0002715///regulation of natural killer cell mediated immunity+++GO:0019882///antigen processing and presentation+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0002717///positive regulation of natural killer cell mediated immunity+++GO:0032759///positive regulation of TRAIL production+++GO:0006955///immune response+++GO:0060337///type I interferon signaling pathway+++GO:0001815///positive regulation of antibody-dependent cellular cytotoxicity+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0045087///innate immune response+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0032736///positive regulation of interleukin-13 production+++GO:0050776///regulation of immune response+++GO:0002250///adaptive immune response+++GO:0032819///positive regulation of natural killer cell proliferation+++GO:0002519///natural killer cell tolerance induction+++GO:0002480///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent+++GO:0032753///positive regulation of interleukin-4 production","major histocompatibility complex, class I, E","[HLAE_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, alpha chain E; AltName: Full=MHC class I antigen E; Flags: Precursor;+++[A0A0A8LFF7_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:CDX10596.1};+++[A0A0F7W1Q1_HUMAN|Unreviewed]SubName: Full=Leucocyte Antigen {ECO:0000313|EMBL:CRI06753.1};+++[A0A0F7WBW2_HUMAN|Unreviewed]SubName: Full=Leucocyte Antigen {ECO:0000313|EMBL:CRI06750.1};+++[A8K8M6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78238, highly similar to Homo sapiens major histocompatibility complex, class I, E, mRNA {ECO:0000313|EMBL:BAF85080.1};+++[E2G051_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ADN38247.1}; Flags: Fragment;+++[I3RW89_HUMAN|Unreviewed]SubName: Full=MHC class Ib antigen {ECO:0000313|EMBL:AFK32127.1}; Flags: Fragment;+++[O19682_HUMAN|Unreviewed]SubName: Full=HLA-E {ECO:0000313|EMBL:CAA40172.1}; Flags: Fragment;+++[Q2L6I5_HUMAN|Unreviewed]SubName: Full=Major histocompatibility complex, class I, E {ECO:0000313|EMBL:BAE78609.1};+++[Q6DU44_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain E {ECO:0000313|Ensembl:ENSP00000365817}; SubName: Full=HLA-E protein {ECO:0000313|EMBL:BAF31260.1}; SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ASU09661.1}; SubName: Full=MHC class Ib antigen {ECO:0000313|EMBL:AAT73214.1}; SubName: Full=Major histocompatibility complex, class I, E {ECO:0000313|EMBL:AAH40479.1};+++[Q6DU50_HUMAN|Unreviewed]SubName: Full=HLA-E {ECO:0000313|EMBL:ARB08448.1}; SubName: Full=Leucocyte Antigen {ECO:0000313|EMBL:CRI06751.1}; SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ASU09660.1}; SubName: Full=MHC class Ib antigen {ECO:0000313|EMBL:AAT73208.1}; SubName: Full=Major histocompatibility complex, class I, E {ECO:0000313|EMBL:BAC54925.1}; SubName: Full=Major histocompatibility complex, class I, E, isoform CRA_b {ECO:0000313|EMBL:EAX03291.1};+++[Q6KBZ5_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:CAG29392.1}; Flags: Fragment;+++[Q9MW44_HUMAN|Unreviewed]SubName: Full=MHC antigen {ECO:0000313|EMBL:AAF25962.1}; Flags: Fragment;+++[Q9TNU7_HUMAN|Unreviewed]SubName: Full=HLA-E protein {ECO:0000313|EMBL:CAA05527.1}; Flags: Fragment;+++[S4W2A6_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AGO87012.1}; Flags: Fragment;+++[S5RFZ0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AGS13698.1};+++[W0NTJ0_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHG55089.1}; Flags: Fragment;+++[W0NXW9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AHG55088.1}; Flags: Fragment;"]
[316,"'AOX1'",42,21,28,30.3333333333333,"00380///Tryptophan metabolism+++00830///Retinol metabolism+++00350///Tyrosine metabolism+++00982///Drug metabolism - cytochrome P450+++04630///Jak-STAT signaling pathway+++00750///Vitamin B6 metabolism+++01100///Metabolic pathways+++00280///Valine, leucine and isoleucine degradation+++00760///Nicotinate and nicotinamide metabolism+++01120///Microbial metabolism in diverse environments","H00192///Xanthinuria",null,"R02125///retinal:oxygen oxidoreductase   Retinal + Oxygen + H2O <=> Retinoate + Hydrogen peroxide+++R02657///2,5-Dihydroxybenzoate + Hydrogen peroxide <=> Gentisate aldehyde + Oxygen + H2O+++R08408///Aldehyde:oxygen oxidoreductase   1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-2-pyridone-5-carboxamide + Hydrogen peroxide + H++++R04085///Aldehyde:oxygen oxidoreductase   1-Methylnicotinamide + Oxygen + H2O <=> N1-Methyl-4-pyridone-5-carboxamide + Hydrogen peroxide + H++++R08349///citalopram aldehyde:oxygen oxidoreductase   Citalopram aldehyde + H2O + Oxygen <=> Citalopram propionic acid + Hydrogen peroxide+++R08384///retinal:oxygen oxidoreductase   9-cis-Retinal + Oxygen + H2O <=> 9-cis-Retinoic acid + Hydrogen peroxide+++R03871///(S)-Methylmalonate semialdehyde:oxygen oxidoreductase   Methylmalonate + Hydrogen peroxide <=> (S)-Methylmalonate semialdehyde + Oxygen + H2O+++R04904///5-hydroxyindoleacetaldehyde:oxygen oxidoreductase   5-Hydroxyindoleacetaldehyde + Oxygen + H2O <=> 5-Hydroxyindoleacetate + Hydrogen peroxide+++R01709///pyridoxal:oxygen 4-oxidoreductase   Pyridoxal + Oxygen + H2O <=> 4-Pyridoxate + Hydrogen peroxide","GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0051287///NAD binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0043546///molybdopterin cofactor binding+++GO:0042803///protein homodimerization activity+++GO:0071949///FAD binding+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0102797///geranial:oxygen oxidoreductase activity+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0042802///identical protein binding+++GO:0005506///iron ion binding+++GO:0009055///electron transfer activity+++GO:0004854///xanthine dehydrogenase activity+++GO:0004031///aldehyde oxidase activity+++GO:0051536///iron-sulfur cluster binding+++GO:0102798///heptaldehyde:oxygen oxidoreductase activity","GO:0009115///xanthine catabolic process+++GO:0055114///oxidation-reduction process+++GO:0017144///drug metabolic process+++GO:0042816///vitamin B6 metabolic process+++GO:0022900///electron transport chain","aldehyde oxidase 1","[AOXA_HUMAN|Reviewed]RecName: Full=Aldehyde oxidase {ECO:0000312|HGNC:HGNC:553}; EC=1.2.3.1 {ECO:0000269|PubMed:22996261, ECO:0000269|PubMed:26322824}; AltName: Full=Aldehyde oxidase 1; AltName: Full=Azaheterocycle hydroxylase {ECO:0000305|PubMed:7786031, ECO:0000305|PubMed:9224775}; EC=1.17.3.- {ECO:0000269|PubMed:7786031, ECO:0000269|PubMed:9224775};+++[A0A286LWX1_HUMAN|Unreviewed]SubName: Full=AOX1 {ECO:0000313|EMBL:ASV51292.1};+++[C9J244_HUMAN|Unreviewed]SubName: Full=Aldehyde oxidase {ECO:0000313|Ensembl:ENSP00000392485}; Flags: Fragment;+++[H7BXF7_HUMAN|Unreviewed]SubName: Full=Aldehyde oxidase {ECO:0000313|Ensembl:ENSP00000260930}; Flags: Fragment;+++[H7C3Q1_HUMAN|Unreviewed]SubName: Full=Aldehyde oxidase {ECO:0000313|Ensembl:ENSP00000413326}; Flags: Fragment;"]
[3176,"'HNMT'",82,74,66,74,"00340///Histidine metabolism","H00768///Nonsyndromic autosomal recessive mental retardation (NS-ARMR)",null,"R02155///S-Adenosyl-L-methionine:histamine N-tele-methyltransferase   S-Adenosyl-L-methionine + Histamine <=> S-Adenosyl-L-homocysteine + N-Methylhistamine","GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome","GO:0016740///transferase activity+++GO:0046539///histamine N-methyltransferase activity+++GO:0008170///N-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0032259///methylation+++GO:0007420///brain development+++GO:0001695///histamine catabolic process+++GO:0006548///histidine catabolic process+++GO:0007585///respiratory gaseous exchange","histamine N-methyltransferase","[HNMT_HUMAN|Reviewed]RecName: Full=Histamine N-methyltransferase; Short=HMT; EC=2.1.1.8 {ECO:0000269|PubMed:26206890};+++[B4DWC1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51345, highly similar to Histamine N-methyltransferase {ECO:0000313|EMBL:BAG62983.1};+++[Q9P1Y0_HUMAN|Unreviewed]SubName: Full=Histamine N-methyltransferase {ECO:0000313|EMBL:BAA94473.1}; Flags: Fragment;"]
[3190,"'HNRNPK'",4526,3665,4127,4106,"05203///Viral carcinogenesis+++05168///Herpes simplex infection+++05206///MicroRNAs in cancer+++03040///Spliceosome","H01930///Au-Kline syndrome","M00414///Bloom's syndrome complex",null,"GO:0010494///cytoplasmic stress granule+++GO:0071013///catalytic step 2 spliceosome+++GO:0070062///extracellular exosome+++GO:0002102///podosome+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005925///focal adhesion+++GO:0000790///nuclear chromatin+++GO:0042995///cell projection+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0019904///protein domain specific binding+++GO:0045296///cadherin binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding+++GO:0003723///RNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0072369///regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter+++GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:1902165///regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0016032///viral process+++GO:0045716///positive regulation of low-density lipoprotein particle receptor biosynthetic process+++GO:0016070///RNA metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0048260///positive regulation of receptor-mediated endocytosis","heterogeneous nuclear ribonucleoprotein K","[HNRPK_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein K; Short=hnRNP K; AltName: Full=Transformation up-regulated nuclear protein; Short=TUNP;+++[A0A024R228_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein K, isoform CRA_d {ECO:0000313|EMBL:EAW62681.1};+++[B4DUQ1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54552, highly similar to Heterogeneous nuclear ribonucleoprotein K {ECO:0000313|EMBL:BAG62413.1};+++[Q5EC54_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein K transcript variant {ECO:0000313|EMBL:AAW84289.1};+++[Q5T6W2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein K {ECO:0000313|Ensembl:ENSP00000409456}; Flags: Fragment;+++[S4R359_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein K {ECO:0000313|Ensembl:ENSP00000473957}; Flags: Fragment;+++[S4R457_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein K {ECO:0000313|Ensembl:ENSP00000475098};"]
[3218,"'HOXB8'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0007275///multicellular organism development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0021516///dorsal spinal cord development+++GO:0048705///skeletal system morphogenesis+++GO:0009952///anterior/posterior pattern specification+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0019233///sensory perception of pain+++GO:0008344///adult locomotory behavior+++GO:0007625///grooming behavior+++GO:0006355///regulation of transcription, DNA-templated","homeobox B8","[HXB8_HUMAN|Reviewed]RecName: Full=Homeobox protein Hox-B8; AltName: Full=Homeobox protein Hox-2.4; AltName: Full=Homeobox protein Hox-2D;+++[I3L383_HUMAN|Unreviewed]SubName: Full=Homeobox protein Hox-B8 {ECO:0000313|Ensembl:ENSP00000460254}; Flags: Fragment;+++[I3L3R1_HUMAN|Unreviewed]SubName: Full=Homeobox B8, isoform CRA_a {ECO:0000313|EMBL:EAW94723.1}; SubName: Full=Homeobox protein Hox-B8 {ECO:0000313|Ensembl:ENSP00000460659};+++[Q8N8T3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38903 fis, clone NT2NE2001252, highly similar to HOMEOBOX PROTEIN HOX-B8 {ECO:0000313|EMBL:BAC04730.1};"]
[3267,"'AGFG1'",911,759,753,807.666666666667,"05164///Influenza A",{"$nulls":3},"GO:0043025///neuronal cell body+++GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0042995///cell projection+++GO:0005643///nuclear pore+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005096///GTPase activator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0061024///membrane organization+++GO:0006406///mRNA export from nucleus+++GO:0001675///acrosome assembly+++GO:0051028///mRNA transport+++GO:0007283///spermatogenesis+++GO:0043547///positive regulation of GTPase activity+++GO:0007289///spermatid nucleus differentiation+++GO:0045109///intermediate filament organization","ArfGAP with FG repeats 1","[AGFG1_HUMAN|Reviewed]RecName: Full=Arf-GAP domain and FG repeat-containing protein 1; AltName: Full=HIV-1 Rev-binding protein; AltName: Full=Nucleoporin-like protein RIP; AltName: Full=Rev-interacting protein; AltName: Full=Rev/Rex activation domain-binding protein;+++[A0A024R458_HUMAN|Unreviewed]SubName: Full=HIV-1 Rev binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW70872.1};+++[A0A0S2Z3Y3_HUMAN|Unreviewed]SubName: Full=ArfGAP with FG repeats 1 isoform 4 {ECO:0000313|EMBL:ALQ33584.1}; Flags: Fragment;+++[A0A0S2Z3Z1_HUMAN|Unreviewed]SubName: Full=ArfGAP with FG repeats 1 isoform 3 {ECO:0000313|EMBL:ALQ33583.1}; Flags: Fragment;+++[A0A0S2Z444_HUMAN|Unreviewed]SubName: Full=ArfGAP with FG repeats 1 isoform 1 {ECO:0000313|EMBL:ALQ33581.1}; Flags: Fragment;+++[A0A0S2Z462_HUMAN|Unreviewed]SubName: Full=ArfGAP with FG repeats 1 isoform 2 {ECO:0000313|EMBL:ALQ33582.1}; Flags: Fragment;+++[B8ZZY2_HUMAN|Unreviewed]SubName: Full=Arf-GAP domain and FG repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387154};+++[C9J2I0_HUMAN|Unreviewed]SubName: Full=Arf-GAP domain and FG repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405429}; Flags: Fragment;+++[H7C0S7_HUMAN|Unreviewed]SubName: Full=Arf-GAP domain and FG repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000396469}; Flags: Fragment;"]
[3280,"'HES1'",578,582,599,586.333333333333,"04950///Maturity onset diabetes of the young+++05224///Breast cancer+++05165///Human papillomavirus infection+++04330///Notch signaling pathway+++03460///Fanconi anemia pathway+++05200///Pathways in cancer",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0001078///proximal promoter DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0071820///N-box binding+++GO:0051087///chaperone binding+++GO:0008134///transcription factor binding+++GO:0042826///histone deacetylase binding+++GO:0043565///sequence-specific DNA binding","GO:0031016///pancreas development+++GO:2000974///negative regulation of pro-B cell differentiation+++GO:0007224///smoothened signaling pathway+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0030901///midbrain development+++GO:0042102///positive regulation of T cell proliferation+++GO:0065003///protein-containing complex assembly+++GO:0061309///cardiac neural crest cell development involved in outflow tract morphogenesis+++GO:2000737///negative regulation of stem cell differentiation+++GO:0048844///artery morphogenesis+++GO:0016477///cell migration+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0060253///negative regulation of glial cell proliferation+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0050678///regulation of epithelial cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0035019///somatic stem cell population maintenance+++GO:0006351///transcription, DNA-templated+++GO:0097150///neuronal stem cell population maintenance+++GO:2000978///negative regulation of forebrain neuron differentiation+++GO:0021537///telencephalon development+++GO:0021575///hindbrain morphogenesis+++GO:0072049///comma-shaped body morphogenesis+++GO:0061106///negative regulation of stomach neuroendocrine cell differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0090102///cochlea development+++GO:0060412///ventricular septum morphogenesis+++GO:0021558///trochlear nerve development+++GO:0003281///ventricular septum development+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0043388///positive regulation of DNA binding+++GO:0021555///midbrain-hindbrain boundary morphogenesis+++GO:0007399///nervous system development+++GO:0097084///vascular smooth muscle cell development+++GO:0048538///thymus development+++GO:0048469///cell maturation+++GO:0060675///ureteric bud morphogenesis+++GO:0090162///establishment of epithelial cell polarity+++GO:0001889///liver development+++GO:0072282///metanephric nephron tubule morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0007219///Notch signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0003266///regulation of secondary heart field cardioblast proliferation+++GO:0045977///positive regulation of mitotic cell cycle, embryonic+++GO:0045608///negative regulation of inner ear auditory receptor cell differentiation+++GO:0045598///regulation of fat cell differentiation+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0003143///embryonic heart tube morphogenesis+++GO:0072141///renal interstitial fibroblast development+++GO:2000227///negative regulation of pancreatic A cell differentiation+++GO:0046425///regulation of JAK-STAT cascade+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0021984///adenohypophysis development+++GO:0060164///regulation of timing of neuron differentiation+++GO:0030324///lung development+++GO:0061009///common bile duct development+++GO:0035910///ascending aorta morphogenesis+++GO:0021861///forebrain radial glial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0060716///labyrinthine layer blood vessel development+++GO:0007155///cell adhesion+++GO:0072012///glomerulus vasculature development+++GO:0072050///S-shaped body morphogenesis+++GO:0046331///lateral inhibition+++GO:0021557///oculomotor nerve development+++GO:0042668///auditory receptor cell fate determination+++GO:0030513///positive regulation of BMP signaling pathway","hes family bHLH transcription factor 1","[HES1_HUMAN|Reviewed]RecName: Full=Transcription factor HES-1; AltName: Full=Class B basic helix-loop-helix protein 39; Short=bHLHb39; AltName: Full=Hairy and enhancer of split 1; AltName: Full=Hairy homolog; AltName: Full=Hairy-like protein; Short=hHL;"]
[3304,"'HSPA1B'",1963.76,1876.74,1764.11,1868.20333333333,"04010///MAPK signaling pathway+++04144///Endocytosis+++05169///Epstein-Barr virus infection+++04915///Estrogen signaling pathway+++05134///Legionellosis+++05164///Influenza A+++05162///Measles+++03040///Spliceosome+++05145///Toxoplasmosis+++04141///Protein processing in endoplasmic reticulum+++04213///Longevity regulating pathway - multiple species+++04612///Antigen processing and presentation",null,"M00353///Spliceosome, Prp19/CDC5L complex+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0016235///aggresome+++GO:0070062///extracellular exosome+++GO:0005856///cytoskeleton+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005634///nucleus+++GO:0072562///blood microparticle+++GO:0005815///microtubule organizing center+++GO:0008180///COP9 signalosome+++GO:1990904///ribonucleoprotein complex+++GO:0000151///ubiquitin ligase complex+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0016234///inclusion body+++GO:0005813///centrosome+++GO:0005783///endoplasmic reticulum+++GO:0031982///vesicle+++GO:0016607///nuclear speck","GO:0044183///protein binding involved in protein folding+++GO:0042826///histone deacetylase binding+++GO:0005102///signaling receptor binding+++GO:0051082///unfolded protein binding+++GO:0047485///protein N-terminus binding+++GO:0016887///ATPase activity+++GO:0001664///G protein-coupled receptor binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0055131///C3HC4-type RING finger domain binding+++GO:0042623///ATPase activity, coupled+++GO:0031625///ubiquitin protein ligase binding+++GO:0051787///misfolded protein binding+++GO:0031072///heat shock protein binding+++GO:0005515///protein binding+++GO:0001618///virus receptor activity+++GO:0005524///ATP binding+++GO:0019899///enzyme binding","GO:0008285///negative regulation of cell proliferation+++GO:0070370///cellular heat acclimation+++GO:0030308///negative regulation of cell growth+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043312///neutrophil degranulation+++GO:0046718///viral entry into host cell+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0034599///cellular response to oxidative stress+++GO:0090063///positive regulation of microtubule nucleation+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:1900034///regulation of cellular response to heat+++GO:0060548///negative regulation of cell death+++GO:0046034///ATP metabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1901673///regulation of mitotic spindle assembly+++GO:0010628///positive regulation of gene expression+++GO:0090084///negative regulation of inclusion body assembly+++GO:0006986///response to unfolded protein+++GO:0050821///protein stabilization+++GO:0010941///regulation of cell death+++GO:0042026///protein refolding+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0006402///mRNA catabolic process+++GO:0031396///regulation of protein ubiquitination+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0032757///positive regulation of interleukin-8 production+++GO:0034620///cellular response to unfolded protein+++GO:0070434///positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0031397///negative regulation of protein ubiquitination+++GO:0034605///cellular response to heat","heat shock protein family A (Hsp70) member 1B","[HS71A_HUMAN|Reviewed]RecName: Full=Heat shock 70 kDa protein 1A {ECO:0000312|HGNC:HGNC:5232}; AltName: Full=Heat shock 70 kDa protein 1; Short=HSP70-1 {ECO:0000303|PubMed:14656967, ECO:0000303|PubMed:2538825}; Short=HSP70.1;+++[HS71B_HUMAN|Reviewed]RecName: Full=Heat shock 70 kDa protein 1B {ECO:0000312|HGNC:HGNC:5233}; AltName: Full=Heat shock 70 kDa protein 2; Short=HSP70-2 {ECO:0000303|PubMed:14656967, ECO:0000303|PubMed:2538825}; Short=HSP70.2;+++[A0A0G2JIW1_HUMAN|Unreviewed]SubName: Full=Heat shock 70 kDa protein 1B {ECO:0000313|Ensembl:ENSP00000402651};+++[A8K5I0_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 103 {ECO:0000313|EMBL:ACI45984.1}; SubName: Full=HSPA1A {ECO:0000313|EMBL:AQY76864.1}; SubName: Full=HSPA1B {ECO:0000313|EMBL:AQY76874.1}; SubName: Full=Heat shock 70kDa protein 1A {ECO:0000313|EMBL:EAX03528.1}; SubName: Full=Heat shock 70kDa protein 1B {ECO:0000313|EMBL:EAX03529.1}; SubName: Full=cDNA FLJ75127, highly similar to Homo sapiens heat shock 70kDa protein 1A, mRNA {ECO:0000313|EMBL:BAF83984.1};"]
[3312,"'HSPA8'",21088,19364,21684,20712,"04010///MAPK signaling pathway+++04915///Estrogen signaling pathway+++04612///Antigen processing and presentation+++04144///Endocytosis+++05164///Influenza A+++04213///Longevity regulating pathway - multiple species+++05169///Epstein-Barr virus infection+++03040///Spliceosome+++05134///Legionellosis+++05162///Measles+++05145///Toxoplasmosis+++04141///Protein processing in endoplasmic reticulum",null,"M00353///Spliceosome, Prp19/CDC5L complex+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005681///spliceosomal complex+++GO:0099523///presynaptic cytosol+++GO:0005634///nucleus+++GO:0042470///melanosome+++GO:0005829///cytosol+++GO:1904813///ficolin-1-rich granule lumen+++GO:0030424///axon+++GO:0099634///postsynaptic specialization membrane+++GO:0098684///photoreceptor ribbon synapse+++GO:0098793///presynapse+++GO:0098978///glutamatergic synapse+++GO:0101031///chaperone complex+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0000974///Prp19 complex+++GO:0005886///plasma membrane+++GO:1990904///ribonucleoprotein complex+++GO:0043209///myelin sheath+++GO:0098575///lumenal side of lysosomal membrane+++GO:0072562///blood microparticle+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0061202///clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane+++GO:0043195///terminal bouton+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0043202///lysosomal lumen+++GO:0070062///extracellular exosome+++GO:0005730///nucleolus+++GO:0099524///postsynaptic cytosol+++GO:0098690///glycinergic synapse+++GO:0034774///secretory granule lumen+++GO:0005776///autophagosome+++GO:0005765///lysosomal membrane+++GO:0005770///late endosome+++GO:0005622///intracellular+++GO:0005576///extracellular region","GO:0044183///protein binding involved in protein folding+++GO:0023026///MHC class II protein complex binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031072///heat shock protein binding+++GO:0016887///ATPase activity+++GO:0051787///misfolded protein binding+++GO:0045296///cadherin binding+++GO:0030674///protein binding, bridging+++GO:0055131///C3HC4-type RING finger domain binding+++GO:0005515///protein binding+++GO:0001786///phosphatidylserine binding+++GO:0000166///nucleotide binding+++GO:0019899///enzyme binding+++GO:0001664///G protein-coupled receptor binding+++GO:0005524///ATP binding+++GO:0051087///chaperone binding+++GO:0003723///RNA binding+++GO:0042623///ATPase activity, coupled+++GO:1990833///clathrin-uncoating ATPase activity+++GO:0051082///unfolded protein binding","GO:0016192///vesicle-mediated transport+++GO:0019221///cytokine-mediated signaling pathway+++GO:0099175///regulation of postsynapse organization+++GO:0008088///axo-dendritic transport+++GO:0042026///protein refolding+++GO:0043312///neutrophil degranulation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0044788///modulation by host of viral process+++GO:0046034///ATP metabolic process+++GO:0061741///chaperone-mediated protein transport involved in chaperone-mediated autophagy+++GO:0000398///mRNA splicing, via spliceosome+++GO:1990832///slow axonal transport+++GO:0043254///regulation of protein complex assembly+++GO:0031647///regulation of protein stability+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:1904764///chaperone-mediated autophagy translocation complex disassembly+++GO:0034605///cellular response to heat+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0061738///late endosomal microautophagy+++GO:0006986///response to unfolded protein+++GO:1902904///negative regulation of supramolecular fiber organization+++GO:0016032///viral process+++GO:1900034///regulation of cellular response to heat+++GO:0061684///chaperone-mediated autophagy+++GO:0006397///mRNA processing+++GO:0061635///regulation of protein complex stability+++GO:0072318///clathrin coat disassembly+++GO:0051726///regulation of cell cycle+++GO:0009267///cellular response to starvation+++GO:0061740///protein targeting to lysosome involved in chaperone-mediated autophagy+++GO:0034620///cellular response to unfolded protein+++GO:0061024///membrane organization+++GO:0006457///protein folding+++GO:0043488///regulation of mRNA stability+++GO:1904589///regulation of protein import+++GO:0061077///chaperone-mediated protein folding+++GO:0008380///RNA splicing+++GO:0044829///positive regulation by host of viral genome replication","heat shock protein family A (Hsp70) member 8","[HSP7C_HUMAN|Reviewed]RecName: Full=Heat shock cognate 71 kDa protein; AltName: Full=Heat shock 70 kDa protein 8; AltName: Full=Lipopolysaccharide-associated protein 1; Short=LAP-1; Short=LPS-associated protein 1;+++[A8K7Q2_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000433316}; SubName: Full=cDNA FLJ77848 {ECO:0000313|EMBL:BAF84756.1};+++[E9PI65_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000436762}; Flags: Fragment;+++[E9PK54_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000431641}; Flags: Fragment;+++[E9PKE3_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000433584};+++[E9PLF4_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000435154}; Flags: Fragment;+++[E9PM13_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000435019}; Flags: Fragment;+++[E9PN25_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000434851}; Flags: Fragment;+++[E9PN89_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000432884}; Flags: Fragment;+++[E9PNE6_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000437189};+++[E9PPY6_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000434565}; Flags: Fragment;+++[E9PQK7_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000436183}; Flags: Fragment;+++[E9PQQ4_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000434415}; Flags: Fragment;+++[E9PS65_HUMAN|Unreviewed]SubName: Full=Heat shock cognate 71 kDa protein {ECO:0000313|Ensembl:ENSP00000435908}; Flags: Fragment;+++[Q53HF2_HUMAN|Unreviewed]SubName: Full=Heat shock 70kDa protein 8 isoform 2 variant {ECO:0000313|EMBL:BAD96348.1}; Flags: Fragment;+++[Q96H53_HUMAN|Unreviewed]SubName: Full=HSPA8 protein {ECO:0000313|EMBL:AAH08907.2}; Flags: Fragment;+++[Q96IS6_HUMAN|Unreviewed]SubName: Full=HSPA8 protein {ECO:0000313|EMBL:AAH07276.2}; Flags: Fragment;+++[V9HW22_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 33 {ECO:0000313|EMBL:ACF94502.1}; SubName: Full=Epididymis secretory sperm binding protein Li 72p {ECO:0000313|EMBL:ACI45986.1}; SubName: Full=Heat shock 70kDa protein 8, isoform CRA_a {ECO:0000313|EMBL:EAW67539.1};"]
[3358,"'HTR2C'",4,5,12,7,"04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04540///Gap junction+++04080///Neuroactive ligand-receptor interaction+++04020///Calcium signaling pathway","H01611///Alcohol dependence+++H01646///Major depressive disorder (MDD)+++H01450///Obsessive-compulsive disorder (OCD)+++H01649///Schizophrenia",null,null,"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite","GO:0051378///serotonin binding+++GO:0030594///neurotransmitter receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0008144///drug binding+++GO:0071886///1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding+++GO:0001587///Gq/11-coupled serotonin receptor activity","GO:0007210///serotonin receptor signaling pathway+++GO:0007208///phospholipase C-activating serotonin receptor signaling pathway+++GO:0006874///cellular calcium ion homeostasis+++GO:0045600///positive regulation of fat cell differentiation+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0007631///feeding behavior+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0031644///regulation of neurological system process+++GO:0007268///chemical synaptic transmission+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007165///signal transduction+++GO:0007610///behavior+++GO:0007626///locomotory behavior+++GO:0001662///behavioral fear response+++GO:0042493///response to drug+++GO:0010513///positive regulation of phosphatidylinositol biosynthetic process+++GO:0019934///cGMP-mediated signaling+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043397///regulation of corticotropin-releasing hormone secretion+++GO:0032098///regulation of appetite+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","5-hydroxytryptamine receptor 2C","[5HT2C_HUMAN|Reviewed]RecName: Full=5-hydroxytryptamine receptor 2C; Short=5-HT-2C; Short=5-HT2C; Short=5-HTR2C; AltName: Full=5-hydroxytryptamine receptor 1C; Short=5-HT-1C; Short=5-HT1C; AltName: Full=Serotonin receptor 2C; Flags: Precursor;+++[B3VRE0_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96328.1}; Flags: Fragment;+++[B3VRE5_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96323.1}; Flags: Fragment;+++[B3VRF0_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96318.1}; Flags: Fragment;+++[B3VRF5_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96313.1}; Flags: Fragment;+++[K9J958_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine receptor-1c variant {ECO:0000313|EMBL:ACO54890.1};+++[Q7Z579_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine receptor 2C variant b {ECO:0000313|EMBL:AAM78371.1}; Flags: Fragment;"]
[337876,"'CHSY3'",89,80,82,83.6666666666667,"00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate+++01100///Metabolic pathways","H01497///Temtamy preaxial brachydactyly syndrome (TPBS)","M00058///Glycosaminoglycan biosynthesis, chondroitin sulfate backbone","R05933///UDP-D-glucuronate + G00160 <=> UDP + G00180+++R05934///UDP-N-acetyl-D-galactosamine + G00180 <=> UDP + G00161+++R04603///UDP-N-acetyl-D-galactosamine:D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan beta-1,4-N-acetylgalactosaminyltransferase   UDP-N-acetyl-D-galactosamine + D-Glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan <=> UDP + N-Acetyl-beta-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan+++R07336///alpha-D-glucuronate:N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan 3-beta-glucuronosyltransferase   UDP-glucuronate + N-Acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan <=> UDP + beta-D-Glucuronosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-glucuronosylproteoglycan+++R05932///UDP-N-acetyl-D-galactosamine + G00159 <=> UDP + G00160+++R05931///UDP-D-glucuronate + G00158 <=> UDP + G00159","GO:0000139///Golgi membrane+++GO:0032580///Golgi cisterna membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0008376///acetylgalactosaminyltransferase activity+++GO:0047238///glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0050510///N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity","GO:0030206///chondroitin sulfate biosynthetic process","chondroitin sulfate synthase 3","[CHSS3_HUMAN|Reviewed]RecName: Full=Chondroitin sulfate synthase 3; EC=2.4.1.175; EC=2.4.1.226; AltName: Full=Carbohydrate synthase 2; AltName: Full=Chondroitin glucuronyltransferase 3; AltName: Full=Chondroitin synthase 2; Short=ChSy-2; AltName: Full=Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; AltName: Full=N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3; AltName: Full=N-acetylgalactosaminyltransferase 3;+++[Q1JTV1_HUMAN|Unreviewed]SubName: Full=Chondroitin synthase {ECO:0000313|EMBL:CAH89316.1};+++[Q3MTV6_HUMAN|Unreviewed]SubName: Full=Chondroitin synthase 2 {ECO:0000313|EMBL:CAG17593.1};"]
[339105,"'PRSS53'",79,81,68,76,"01110///Biosynthesis of secondary metabolites+++00130///Ubiquinone and other terpenoid-quinone biosynthesis","H00995///Combined deficiency of vitamin K-dependent clotting factors (VKCFD)+++H01205///Coumarin resistance",null,"R03645///Vitamin K:oxidized-dithiothreitol oxidoreductase Vitamin K + Oxidized dithiothreitol + H2O <=> Vitamin K epoxide + Dithiothreitol+++R09992///menaquinone:oxidized-dithiothreitol oxidoreductase 2,3-Epoxymenaquinone + Dithiothreitol <=> Menaquinone + Oxidized dithiothreitol + H2O+++R03511///phylloquinone:oxidized-dithiothreitol oxidoreductase Phylloquinone + Oxidized dithiothreitol + H2O <=> Vitamin K1 epoxide + Dithiothreitol","GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0016787///hydrolase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis","serine protease 53","[PRS53_HUMAN|Reviewed]RecName: Full=Serine protease 53; EC=3.4.21.-; AltName: Full=Polyserine protease 3; Short=Polyserase-3; Flags: Precursor;"]
[339263,"'C17orf51'",276,231,236,247.666666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","chromosome 17 open reading frame 51","[CQ051_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf51;+++[H0YGX3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf51 {ECO:0000313|Ensembl:ENSP00000445158};"]
[339745,"'SPOPL'",130,106,110,115.333333333333,"04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway",null,"M00384///Cul3-SPOP complex",null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031463///Cul3-RING ubiquitin ligase complex","GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030162///regulation of proteolysis+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0016567///protein ubiquitination","speckle type BTB/POZ protein like","[SPOPL_HUMAN|Reviewed]RecName: Full=Speckle-type POZ protein-like; AltName: Full=HIB homolog 2; AltName: Full=Roadkill homolog 2;+++[F8WBB7_HUMAN|Unreviewed]SubName: Full=Speckle-type POZ protein-like {ECO:0000313|Ensembl:ENSP00000410201};+++[F8WD02_HUMAN|Unreviewed]SubName: Full=Speckle-type POZ protein-like {ECO:0000313|Ensembl:ENSP00000396006};"]
[3399,"'ID3'",1562,1981,1448,1663.66666666667,"04350///TGF-beta signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0046983///protein dimerization activity+++GO:0003714///transcription corepressor activity+++GO:1901707///leptomycin B binding","GO:0045668///negative regulation of osteoblast differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0001656///metanephros development+++GO:0009611///response to wounding+++GO:0072750///cellular response to leptomycin B+++GO:0010629///negative regulation of gene expression+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045662///negative regulation of myoblast differentiation+++GO:0045665///negative regulation of neuron differentiation+++GO:0030903///notochord development+++GO:0006351///transcription, DNA-templated+++GO:0043392///negative regulation of DNA binding+++GO:0007517///muscle organ development+++GO:0048511///rhythmic process+++GO:0051726///regulation of cell cycle+++GO:0030855///epithelial cell differentiation+++GO:0007623///circadian rhythm+++GO:0006275///regulation of DNA replication+++GO:0042476///odontogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007417///central nervous system development+++GO:0007507///heart development+++GO:0007275///multicellular organism development+++GO:0030182///neuron differentiation","inhibitor of DNA binding 3, HLH protein","[ID3_HUMAN|Reviewed]RecName: Full=DNA-binding protein inhibitor ID-3; AltName: Full=Class B basic helix-loop-helix protein 25; Short=bHLHb25; AltName: Full=Helix-loop-helix protein HEIR-1; AltName: Full=ID-like protein inhibitor HLH 1R21; AltName: Full=Inhibitor of DNA binding 3; AltName: Full=Inhibitor of differentiation 3;+++[A0A024RAC4_HUMAN|Unreviewed]SubName: Full=Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein, isoform CRA_a {ECO:0000313|EMBL:EAW95061.1};"]
[340390,"'WDR97'",21,20,20,20.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"WD repeat domain 97","[WDR97_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 97 {ECO:0000312|HGNC:HGNC:26959};+++[E9PKB8_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 97 {ECO:0000313|Ensembl:ENSP00000435391};"]
[340562,"'SATL1'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0019809///spermidine binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004145///diamine N-acetyltransferase activity","GO:0032918///spermidine acetylation","spermidine/spermine N1-acetyl transferase like 1","[SATL1_HUMAN|Reviewed]RecName: Full=Spermidine/spermine N(1)-acetyltransferase-like protein 1; EC=2.3.1.-;+++[A0A2R8Y5C1_HUMAN|Unreviewed]SubName: Full=Spermidine/spermine N(1)-acetyltransferase-like protein 1 {ECO:0000313|Ensembl:ENSP00000494345};+++[A0A2R8YFQ0_HUMAN|Unreviewed]SubName: Full=Spermidine/spermine N(1)-acetyltransferase-like protein 1 {ECO:0000313|Ensembl:ENSP00000495329};"]
[341676,"'NEK5'",11.75,10.35,11,11.0333333333333,null,"H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",{"$nulls":3},"GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity","GO:2001056///positive regulation of cysteine-type endopeptidase activity+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0051155///positive regulation of striated muscle cell differentiation","NIMA related kinase 5","[NEK5_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Nek5; EC=2.7.11.1; AltName: Full=Never in mitosis A-related kinase 5; Short=NimA-related protein kinase 5;+++[E9PIX7_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek5 {ECO:0000313|Ensembl:ENSP00000431956};"]
[342346,"'C16orf96'",22,17,15,18,{"$nulls":7},"chromosome 16 open reading frame 96","[CP096_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C16orf96 {ECO:0000305};"]
[342945,"'ZSCAN22'",95.48,84.07,117.14,98.8966666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and SCAN domain containing 22","[ZSC22_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 22; AltName: Full=Krueppel-related zinc finger protein 2; AltName: Full=Protein HKR2; AltName: Full=Zinc finger protein 50;"]
[343521,"'TCTEX1D4'",4,3,6,4.33333333333333,"04068///FoxO signaling pathway+++05152///Tuberculosis+++04625///C-type lectin receptor signaling pathway",{"$nulls":3},"GO:0001669///acrosomal vesicle+++GO:0005930///axoneme+++GO:0036126///sperm flagellum+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0090316///positive regulation of intracellular protein transport+++GO:2000777///positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia+++GO:0043491///protein kinase B signaling+++GO:1904716///positive regulation of chaperone-mediated autophagy+++GO:0007093///mitotic cell cycle checkpoint+++GO:0009314///response to radiation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0007113///endomitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0031122///cytoplasmic microtubule organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0000302///response to reactive oxygen species+++GO:0090166///Golgi disassembly+++GO:0043066///negative regulation of apoptotic process+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006915///apoptotic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032465///regulation of cytokinesis+++GO:0044819///mitotic G1/S transition checkpoint+++GO:0006970///response to osmotic stress+++GO:0051302///regulation of cell division","Tctex1 domain containing 4","[TC1D4_HUMAN|Reviewed]RecName: Full=Tctex1 domain-containing protein 4; AltName: Full=Protein N22.1; AltName: Full=Tctex-2-beta;"]
[344905,"'ATP13A5'",2,2,1,1.66666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0019829///cation-transporting ATPase activity+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0005524///ATP binding+++GO:0046872///metal ion binding","GO:0006812///cation transport+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport","ATPase 13A5","[AT135_HUMAN|Reviewed]RecName: Full=Probable cation-transporting ATPase 13A5; EC=3.6.3.-; AltName: Full=P5-ATPase isoform 5;+++[A0A087X108_HUMAN|Unreviewed]SubName: Full=Probable cation-transporting ATPase 13A5 {ECO:0000313|Ensembl:ENSP00000483801};+++[C9JPQ4_HUMAN|Unreviewed]SubName: Full=Probable cation-transporting ATPase 13A5 {ECO:0000313|Ensembl:ENSP00000389416}; Flags: Fragment;"]
[345930,"'ECT2L'",1,0,0,0.333333333333333,"04060///Cytokine-cytokine receptor interaction+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0055037///recycling endosome+++GO:0005769///early endosome+++GO:0005886///plasma membrane","GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0035023///regulation of Rho protein signal transduction","epithelial cell transforming 2 like","[ECT2L_HUMAN|Reviewed]RecName: Full=Epithelial cell-transforming sequence 2 oncogene-like; AltName: Full=Lung-specific F-box and DH domain-containing protein; AltName: Full=Putative guanine nucleotide exchange factor LFDH;+++[A0A2X0SFI5_HUMAN|Unreviewed]SubName: Full=ECT2L {ECO:0000313|EMBL:SPT35753.1}; Flags: Fragment;+++[B7ZBI6_HUMAN|Unreviewed]SubName: Full=Epithelial cell-transforming sequence 2 oncogene-like {ECO:0000313|Ensembl:ENSP00000385187}; Flags: Fragment;"]
[3460,"'IFNGR2'",782,868,682,777.333333333333,"04630///Jak-STAT signaling pathway+++05162///Measles+++04217///Necroptosis+++05200///Pathways in cancer+++05321///Inflammatory bowel disease (IBD)+++04659///Th17 cell differentiation+++05145///Toxoplasmosis+++04658///Th1 and Th2 cell differentiation+++05164///Influenza A+++05142///Chagas disease (American trypanosomiasis)+++04066///HIF-1 signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04650///Natural killer cell mediated cytotoxicity+++05152///Tuberculosis+++04380///Osteoclast differentiation+++05140///Leishmaniasis+++05132///Salmonella infection+++05168///Herpes simplex infection","H00342///Tuberculosis+++H00089///IFN-gamma/IL-12 axis",null,null,"GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm","GO:0004906///interferon-gamma receptor activity","GO:0009615///response to virus+++GO:0019221///cytokine-mediated signaling pathway+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0051607///defense response to virus+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway","interferon gamma receptor 2","[INGR2_HUMAN|Reviewed]RecName: Full=Interferon gamma receptor 2 {ECO:0000312|HGNC:HGNC:5440}; Short=IFN-gamma receptor 2; Short=IFN-gamma-R2; AltName: Full=Interferon gamma receptor accessory factor 1 {ECO:0000303|PubMed:8124716}; Short=AF-1 {ECO:0000303|PubMed:8124716}; AltName: Full=Interferon gamma receptor beta-chain {ECO:0000303|PubMed:7615558}; Short=IFN-gamma-R-beta {ECO:0000303|PubMed:7615558}; AltName: Full=Interferon gamma transducer 1 {ECO:0000312|HGNC:HGNC:5440}; Flags: Precursor;+++[A0A0G2JLC6_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000459355}; Flags: Fragment;+++[A0A0G2JLD7_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000459965}; Flags: Fragment;+++[A0A0G2JLE2_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000460732}; Flags: Fragment;+++[A0A0G2JLE8_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000461231}; Flags: Fragment;+++[A8K881_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 (Interferon gamma transducer 1), isoform CRA_a {ECO:0000313|EMBL:EAX09834.1}; SubName: Full=cDNA FLJ78008, highly similar to Human clone pSK1 interferon gamma receptor accessory factor-1 (AF-1) mRNA {ECO:0000313|EMBL:BAF84935.1}; SubName: Full=cDNA, FLJ94659, highly similar to Homo sapiens interferon gamma receptor 2 (interferon gammatransducer 1) (IFNGR2), mRNA {ECO:0000313|EMBL:BAG36717.1};+++[B5MCZ0_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 (Interferon gamma transducer 1), isoform CRA_b {ECO:0000313|EMBL:EAX09835.1};+++[E7EUY1_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000371425};+++[F8WE34_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000442735};+++[F8WF11_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000407541};+++[H7C1V5_HUMAN|Unreviewed]SubName: Full=Interferon gamma receptor 2 {ECO:0000313|Ensembl:ENSP00000402629}; Flags: Fragment;"]
[347273,"'CAVIN4'",31,27,22,26.6666666666667,{"$nulls":4},"GO:0042383///sarcolemma+++GO:0005886///plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0030017///sarcomere+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation","caveolae associated protein 4","[CAVN4_HUMAN|Reviewed]RecName: Full=Caveolae-associated protein 4 {ECO:0000312|HGNC:HGNC:33742}; AltName: Full=Muscle-related coiled-coil protein; AltName: Full=Muscle-restricted coiled-coil protein;"]
[347735,"'SERINC2'",2798,3229,2842,2956.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0015194///L-serine transmembrane transporter activity","GO:1904222///positive regulation of serine C-palmitoyltransferase activity+++GO:1904219///positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0006658///phosphatidylserine metabolic process+++GO:0006665///sphingolipid metabolic process","serine incorporator 2","[SERC2_HUMAN|Reviewed]RecName: Full=Serine incorporator 2; AltName: Full=Tumor differentially expressed protein 2-like;+++[D3DPN6_HUMAN|Unreviewed]SubName: Full=Serine incorporator 2, isoform CRA_b {ECO:0000313|EMBL:EAX07613.1};+++[Q96AI1_HUMAN|Unreviewed]SubName: Full=SERINC2 protein {ECO:0000313|EMBL:AAH17085.2}; Flags: Fragment;+++[Q96IM8_HUMAN|Unreviewed]SubName: Full=SERINC2 protein {ECO:0000313|EMBL:AAH07375.2}; Flags: Fragment;"]
[348262,"'MCRIP1'",1305,1608,1362,1425,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0010717///regulation of epithelial to mesenchymal transition","MAPK regulated corepressor interacting protein 1","[MCRI1_HUMAN|Reviewed]RecName: Full=Mapk-regulated corepressor-interacting protein 1 {ECO:0000303|PubMed:25728771}; AltName: Full=Granulin-2 {ECO:0000303|PubMed:26184334}; AltName: Full=Protein FAM195B;+++[A0A024R8R5_HUMAN|Unreviewed]SubName: Full=HCG1818442, isoform CRA_c {ECO:0000313|EMBL:EAW89688.1};+++[I3L2L5_HUMAN|Unreviewed]SubName: Full=Mapk-regulated corepressor-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000459769};+++[I3L317_HUMAN|Unreviewed]SubName: Full=Mapk-regulated corepressor-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000460100};+++[I3L3A7_HUMAN|Unreviewed]SubName: Full=Mapk-regulated corepressor-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000460299};+++[I3L3C1_HUMAN|Unreviewed]SubName: Full=Mapk-regulated corepressor-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000460329};+++[I3L4Q0_HUMAN|Unreviewed]SubName: Full=HCG1818442, isoform CRA_a {ECO:0000313|EMBL:EAW89685.1}; SubName: Full=Mapk-regulated corepressor-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000461433};"]
[3489,"'IGFBP6'",377,477,307,387,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0042568///insulin-like growth factor binary complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus","GO:0031994///insulin-like growth factor I binding+++GO:0031995///insulin-like growth factor II binding+++GO:0005102///signaling receptor binding+++GO:0005520///insulin-like growth factor binding+++GO:0001968///fibronectin binding+++GO:0019838///growth factor binding","GO:0044267///cellular protein metabolic process+++GO:0007165///signal transduction+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0001558///regulation of cell growth","insulin like growth factor binding protein 6","[IBP6_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor-binding protein 6; Short=IBP-6; Short=IGF-binding protein 6; Short=IGFBP-6; Flags: Precursor;+++[F8VVA5_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor-binding protein 6 {ECO:0000313|Ensembl:ENSP00000449344};+++[F8VYK9_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor-binding protein 6 {ECO:0000313|Ensembl:ENSP00000448953};+++[Q9H2B5_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor binding protein 6 {ECO:0000313|EMBL:AAG37059.1}; Flags: Fragment;"]
[3516,"'RBPJ'",896,727,748,790.333333333333,"04330///Notch signaling pathway+++05169///Epstein-Barr virus infection+++05165///Human papillomavirus infection+++04658///Th1 and Th2 cell differentiation+++05203///Viral carcinogenesis","H01413///Adams-Oliver syndrome (AOS)","M00682///Notch signaling",null,"GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex","GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0047485///protein N-terminus binding+++GO:0000150///recombinase activity+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0070491///repressing transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0003160///endocardium morphogenesis+++GO:0048820///hair follicle maturation+++GO:0003151///outflow tract morphogenesis+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0048844///artery morphogenesis+++GO:0030097///hemopoiesis+++GO:0006959///humoral immune response+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0061419///positive regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0097101///blood vessel endothelial cell fate specification+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0003139///secondary heart field specification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0003256///regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000138///positive regulation of cell proliferation involved in heart morphogenesis+++GO:0007507///heart development+++GO:0060486///Clara cell differentiation+++GO:0003177///pulmonary valve development+++GO:0042127///regulation of cell proliferation+++GO:0009957///epidermal cell fate specification+++GO:0001974///blood vessel remodeling+++GO:0036302///atrioventricular canal development+++GO:1901297///positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment+++GO:0009912///auditory receptor cell fate commitment+++GO:0007219///Notch signaling pathway+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0061314///Notch signaling involved in heart development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0030183///B cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0072602///interleukin-4 secretion+++GO:0003176///aortic valve development+++GO:0045596///negative regulation of cell differentiation+++GO:0035912///dorsal aorta morphogenesis+++GO:0060844///arterial endothelial cell fate commitment+++GO:0043011///myeloid dendritic cell differentiation+++GO:0030279///negative regulation of ossification+++GO:0008285///negative regulation of cell proliferation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0003157///endocardium development+++GO:0048505///regulation of timing of cell differentiation+++GO:0060412///ventricular septum morphogenesis+++GO:0006310///DNA recombination+++GO:0045165///cell fate commitment+++GO:1901189///positive regulation of ephrin receptor signaling pathway+++GO:0060716///labyrinthine layer blood vessel development+++GO:0001837///epithelial to mesenchymal transition+++GO:1901186///positive regulation of ERBB signaling pathway+++GO:0030182///neuron differentiation+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0030216///keratinocyte differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0048733///sebaceous gland development+++GO:0021983///pituitary gland development+++GO:0072554///blood vessel lumenization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0001756///somitogenesis+++GO:0042742///defense response to bacterium+++GO:0001525///angiogenesis+++GO:0010628///positive regulation of gene expression+++GO:0035019///somatic stem cell population maintenance","recombination signal binding protein for immunoglobulin kappa J region","[SUH_HUMAN|Reviewed]RecName: Full=Recombining binding protein suppressor of hairless; AltName: Full=CBF-1; AltName: Full=J kappa-recombination signal-binding protein; AltName: Full=RBP-J kappa; Short=RBP-J; Short=RBP-JK; AltName: Full=Renal carcinoma antigen NY-REN-30;+++[A0A024R9Q8_HUMAN|Unreviewed]SubName: Full=Recombining binding protein suppressor of hairless (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW92848.1};+++[D6R927_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000423703};+++[D6R946_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000423644}; Flags: Fragment;+++[D6R9K5_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000423575}; Flags: Fragment;+++[D6R9X3_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000422838}; Flags: Fragment;+++[D6RA45_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000423406}; Flags: Fragment;+++[D6RAT2_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000424789}; Flags: Fragment;+++[D6RB37_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000424459}; Flags: Fragment;+++[D6RBQ8_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000422617}; Flags: Fragment;+++[D6RCM1_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000427170}; Flags: Fragment;+++[D6RE93_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000426872}; Flags: Fragment;+++[D6REC2_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000425061}; Flags: Fragment;+++[D6REP3_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000424989}; Flags: Fragment;+++[D6RF98_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000424804}; Flags: Fragment;+++[D6RIV8_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000427344};+++[D6RIZ8_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000425750}; Flags: Fragment;+++[H0Y8R3_HUMAN|Unreviewed]SubName: Full=Recombining-binding protein suppressor of hairless {ECO:0000313|Ensembl:ENSP00000421804}; Flags: Fragment;+++[L8E7S3_HUMAN|Unreviewed]SubName: Full=Alternative protein RBPJ {ECO:0000313|EMBL:CCQ43315.1};+++[Q14663_HUMAN|Unreviewed]SubName: Full=H-2K binding factor-2 {ECO:0000313|EMBL:AAA91836.1};"]
[3547,"'IGSF1'",1,3,3,2.33333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region","GO:0034711///inhibin binding+++GO:0015026///coreceptor activity+++GO:0038102///activin receptor antagonist activity+++GO:0005515///protein binding","GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0006355///regulation of transcription, DNA-templated","immunoglobulin superfamily member 1","[IGSF1_HUMAN|Reviewed]RecName: Full=Immunoglobulin superfamily member 1; Short=IgSF1; AltName: Full=Immunoglobulin-like domain-containing protein 1; AltName: Full=Inhibin-binding protein; Short=InhBP; AltName: Full=Pituitary gland-specific factor 2; AltName: Full=p120; Flags: Precursor;"]
[3569,"'IL6'",9,22,17,16,"01523///Antifolate resistance+++04620///Toll-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++05162///Measles+++04668///TNF signaling pathway+++05132///Salmonella infection+++05020///Prion diseases+++05168///Herpes simplex infection+++04659///Th17 cell differentiation+++04630///Jak-STAT signaling pathway+++05146///Amoebiasis+++05134///Legionellosis+++05164///Influenza A+++04151///PI3K-Akt signaling pathway+++04623///Cytosolic DNA-sensing pathway+++04931///Insulin resistance+++05202///Transcriptional misregulation in cancer+++04640///Hematopoietic cell lineage+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04657///IL-17 signaling pathway+++05143///African trypanosomiasis+++05410///Hypertrophic cardiomyopathy (HCM)+++04933///AGE-RAGE signaling pathway in diabetic complications+++04060///Cytokine-cytokine receptor interaction+++05200///Pathways in cancer+++04066///HIF-1 signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++05161///Hepatitis B+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05323///Rheumatoid arthritis+++05163///Human cytomegalovirus infection+++05166///HTLV-I infection+++05332///Graft-versus-host disease+++05152///Tuberculosis+++04218///Cellular senescence+++05133///Pertussis+++04068///FoxO signaling pathway+++05144///Malaria+++05321///Inflammatory bowel disease (IBD)+++04625///C-type lectin receptor signaling pathway+++04672///Intestinal immune network for IgA production+++01521///EGFR tyrosine kinase inhibitor resistance","H00084///Graft-versus-host disease+++H01672///Juvenile idiopathic arthritis (JIA)+++H01479///Castleman disease",null,null,"GO:0005896///interleukin-6 receptor complex+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0005615///extracellular space","GO:0005138///interleukin-6 receptor binding+++GO:0008083///growth factor activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding","GO:0006954///inflammatory response+++GO:0045779///negative regulation of bone resorption+++GO:0070050///neuron cellular homeostasis+++GO:0051384///response to glucocorticoid+++GO:1905603///regulation of maintenance of permeability of blood-brain barrier+++GO:0002675///positive regulation of acute inflammatory response+++GO:0061888///regulation of astrocyte activation+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0150078///positive regulation of neuroinflammatory response+++GO:0050871///positive regulation of B cell activation+++GO:0050830///defense response to Gram-positive bacterium+++GO:0070091///glucagon secretion+++GO:0042102///positive regulation of T cell proliferation+++GO:0150077///regulation of neuroinflammatory response+++GO:0010574///regulation of vascular endothelial growth factor production+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043065///positive regulation of apoptotic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:1903978///regulation of microglial cell activation+++GO:0002384///hepatic immune response+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0044267///cellular protein metabolic process+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0002446///neutrophil mediated immunity+++GO:0070301///cellular response to hydrogen peroxide+++GO:0045079///negative regulation of chemokine biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0010469///regulation of signaling receptor activity+++GO:0006953///acute-phase response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0060252///positive regulation of glial cell proliferation+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0043066///negative regulation of apoptotic process+++GO:0050768///negative regulation of neurogenesis+++GO:0006955///immune response+++GO:0045765///regulation of angiogenesis+++GO:0002548///monocyte chemotaxis+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0001781///neutrophil apoptotic process+++GO:0031175///neuron projection development+++GO:0072540///T-helper 17 cell lineage commitment+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0006959///humoral immune response+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045727///positive regulation of translation+++GO:0032722///positive regulation of chemokine production+++GO:0043410///positive regulation of MAPK cascade+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:0032494///response to peptidoglycan+++GO:0032755///positive regulation of interleukin-6 production+++GO:0030168///platelet activation+++GO:2000660///negative regulation of interleukin-1-mediated signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0051607///defense response to virus+++GO:0031018///endocrine pancreas development+++GO:0050829///defense response to Gram-negative bacterium+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0043687///post-translational protein modification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0010888///negative regulation of lipid storage","interleukin 6","[IL6_HUMAN|Reviewed]RecName: Full=Interleukin-6; Short=IL-6; AltName: Full=B-cell stimulatory factor 2; Short=BSF-2; AltName: Full=CTL differentiation factor; Short=CDF; AltName: Full=Hybridoma growth factor; AltName: Full=Interferon beta-2; Short=IFN-beta-2; Flags: Precursor;+++[A0A1C9J7T5_HUMAN|Unreviewed]SubName: Full=Interleukin 6 {ECO:0000313|EMBL:AOP17755.1}; Flags: Fragment;+++[A0A1C9J7T7_HUMAN|Unreviewed]SubName: Full=Interleukin 6 {ECO:0000313|EMBL:AOP17753.1}; Flags: Fragment;+++[A0A1C9J7T8_HUMAN|Unreviewed]SubName: Full=Interleukin 6 {ECO:0000313|EMBL:AOP17754.1}; Flags: Fragment;+++[A0A1C9J7U0_HUMAN|Unreviewed]SubName: Full=Interleukin 6 {ECO:0000313|EMBL:AOP17758.1}; Flags: Fragment;+++[A0A1C9J7V0_HUMAN|Unreviewed]SubName: Full=Interleukin 6 {ECO:0000313|EMBL:AOP17756.1}; Flags: Fragment;+++[A0A1C9J7V2_HUMAN|Unreviewed]SubName: Full=Truncated interleukin 6 {ECO:0000313|EMBL:AOP17757.1}; Flags: Fragment;+++[B4DNQ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55231, highly similar to Interleukin-6 {ECO:0000313|EMBL:BAG60317.1};+++[B4DNV3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52006, moderately similar to Interleukin-6 {ECO:0000313|EMBL:BAG60365.1};+++[B4DVM1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61423, highly similar to Interleukin-6 {ECO:0000313|EMBL:BAG62733.1};+++[B5MC14_HUMAN|Unreviewed]SubName: Full=Interleukin-6 {ECO:0000313|Ensembl:ENSP00000385227};+++[B5MC21_HUMAN|Unreviewed]SubName: Full=Interleukin-6 {ECO:0000313|Ensembl:ENSP00000385043};+++[B5MCZ3_HUMAN|Unreviewed]SubName: Full=Interleukin-6 {ECO:0000313|Ensembl:ENSP00000384928};+++[C9J5B0_HUMAN|Unreviewed]SubName: Full=Interleukin-6 {ECO:0000313|Ensembl:ENSP00000405150}; Flags: Fragment;+++[Q75MH2_HUMAN|Unreviewed]SubName: Full=IL6 protein {ECO:0000313|EMBL:CAG29292.1}; SubName: Full=Interleukin 6 (Interferon, beta 2) {ECO:0000313|EMBL:AAV38553.1}; SubName: Full=Interleukin 6 (Interferon, beta 2), isoform CRA_a {ECO:0000313|EMBL:EAW93756.1};"]
[360,"'AQP3'",14,14,13,13.6666666666667,"04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane+++GO:0016021///integral component of membrane+++GO:0005911///cell-cell junction","GO:0005215///transporter activity+++GO:0015254///glycerol channel activity+++GO:0015267///channel activity+++GO:0015250///water channel activity","GO:0070295///renal water absorption+++GO:0051592///response to calcium ion+++GO:0055085///transmembrane transport+++GO:0045616///regulation of keratinocyte differentiation+++GO:0033280///response to vitamin D+++GO:0042476///odontogenesis+++GO:0071456///cellular response to hypoxia+++GO:0032526///response to retinoic acid+++GO:0015840///urea transport+++GO:0015793///glycerol transport+++GO:0007588///excretion+++GO:0006833///water transport+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0003091///renal water homeostasis+++GO:0002684///positive regulation of immune system process","aquaporin 3 (Gill blood group)","[AQP3_HUMAN|Reviewed]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=Aquaglyceroporin-3;+++[A0A2R8Y2R4_HUMAN|Unreviewed]SubName: Full=Aquaporin 3 (Gill blood group), isoform CRA_d {ECO:0000313|EMBL:EAW58503.1}; SubName: Full=Aquaporin-3 {ECO:0000313|Ensembl:ENSP00000493516};+++[A0A2R8YD22_HUMAN|Unreviewed]SubName: Full=Aquaporin-3 {ECO:0000313|Ensembl:ENSP00000493567};+++[A0A2R8YDV4_HUMAN|Unreviewed]SubName: Full=Aquaporin-3 {ECO:0000313|Ensembl:ENSP00000494946}; Flags: Fragment;+++[B4E034_HUMAN|Unreviewed]SubName: Full=Aquaporin 3 (Gill blood group), isoform CRA_c {ECO:0000313|EMBL:EAW58502.1}; SubName: Full=cDNA FLJ57062, highly similar to Aquaporin-3 {ECO:0000313|EMBL:BAG64296.1};"]
[3611,"'ILK'",2167,2448,2017,2210.66666666667,"05213///Endometrial cancer+++03320///PPAR signaling pathway+++04510///Focal adhesion+++04360///Axon guidance+++05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0030424///axon+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0005911///cell-cell junction+++GO:0001725///stress fiber+++GO:0043034///costamere+++GO:0043198///dendritic shaft+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0043195///terminal bouton+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0005654///nucleoplasm+++GO:0030017///sarcomere+++GO:0043025///neuronal cell body+++GO:0032991///protein-containing complex","GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0019904///protein domain specific binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0017124///SH3 domain binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding+++GO:0005178///integrin binding","GO:0045669///positive regulation of osteoblast differentiation+++GO:0048812///neuron projection morphogenesis+++GO:0030030///cell projection organization+++GO:0050772///positive regulation of axonogenesis+++GO:0034329///cell junction assembly+++GO:0043410///positive regulation of MAPK cascade+++GO:0009967///positive regulation of signal transduction+++GO:0030335///positive regulation of cell migration+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0097435///supramolecular fiber organization+++GO:0016310///phosphorylation+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0022011///myelination in peripheral nervous system+++GO:0051291///protein heterooligomerization+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0006468///protein phosphorylation+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006469///negative regulation of protein kinase activity+++GO:0045773///positive regulation of axon extension+++GO:0007160///cell-matrix adhesion+++GO:0000165///MAPK cascade+++GO:0001558///regulation of cell growth+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0007050///cell cycle arrest+++GO:0045663///positive regulation of myoblast differentiation+++GO:0042327///positive regulation of phosphorylation+++GO:0010761///fibroblast migration+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0014044///Schwann cell development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0032288///myelin assembly+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0008283///cell proliferation+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043066///negative regulation of apoptotic process+++GO:0021675///nerve development+++GO:0008284///positive regulation of cell proliferation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0043491///protein kinase B signaling+++GO:0003151///outflow tract morphogenesis+++GO:0007229///integrin-mediated signaling pathway+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0070527///platelet aggregation+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:0043406///positive regulation of MAP kinase activity+++GO:0007569///cell aging","integrin linked kinase","[ILK_HUMAN|Reviewed]RecName: Full=Integrin-linked protein kinase; EC=2.7.11.1; AltName: Full=59 kDa serine/threonine-protein kinase; AltName: Full=ILK-1; AltName: Full=ILK-2; AltName: Full=p59ILK;+++[A0A087WW45_HUMAN|Unreviewed]SubName: Full=Integrin-linked protein kinase {ECO:0000313|Ensembl:ENSP00000479932};+++[A0A087WWY6_HUMAN|Unreviewed]SubName: Full=Integrin-linked protein kinase {ECO:0000313|Ensembl:ENSP00000480597}; Flags: Fragment;+++[A0A0A0MTH3_HUMAN|Unreviewed]SubName: Full=Integrin-linked protein kinase {ECO:0000313|Ensembl:ENSP00000439606};+++[E9PQ52_HUMAN|Unreviewed]SubName: Full=Integrin-linked protein kinase {ECO:0000313|Ensembl:ENSP00000432617};+++[V9HWF0_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 28 {ECO:0000313|EMBL:ACJ13679.1};"]
[3636,"'INPPL1'",4465,4144,4189,4266,"04662///B cell receptor signaling pathway+++04910///Insulin signaling pathway+++04070///Phosphatidylinositol signaling system+++04666///Fc gamma R-mediated phagocytosis+++00562///Inositol phosphate metabolism","H01828///Opsismodysplasia",null,"R09827///1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase   Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate","GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0030175///filopodium+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0017124///SH3 domain binding+++GO:0016787///hydrolase activity+++GO:0052659///inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0042169///SH2 domain binding+++GO:0005515///protein binding+++GO:0003779///actin binding","GO:0008285///negative regulation of cell proliferation+++GO:0006897///endocytosis+++GO:0007155///cell adhesion+++GO:0006006///glucose metabolic process+++GO:0007015///actin filament organization+++GO:0044255///cellular lipid metabolic process+++GO:0002376///immune system process+++GO:0032868///response to insulin+++GO:0043647///inositol phosphate metabolic process+++GO:0010629///negative regulation of gene expression+++GO:0009791///post-embryonic development+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0097178///ruffle assembly+++GO:0001958///endochondral ossification+++GO:0046856///phosphatidylinositol dephosphorylation","inositol polyphosphate phosphatase like 1","[SHIP2_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; EC=3.1.3.86; AltName: Full=Inositol polyphosphate phosphatase-like protein 1; Short=INPPL-1; AltName: Full=Protein 51C; AltName: Full=SH2 domain-containing inositol 5'-phosphatase 2; Short=SH2 domain-containing inositol phosphatase 2; Short=SHIP-2;+++[A0A0A0MTP6_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000446360};+++[F5GWY9_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000440512}; Flags: Fragment;+++[F5GY16_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000440018}; Flags: Fragment;+++[F5GYK9_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000440904}; Flags: Fragment;+++[F5H588_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000444630}; Flags: Fragment;+++[H0YFB4_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000437852}; Flags: Fragment;+++[H0YFZ4_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000441094}; Flags: Fragment;+++[H7BXR2_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 {ECO:0000313|Ensembl:ENSP00000321775}; Flags: Fragment;"]
[3658,"'IREB2'",488,334,442,421.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0030424///axon","GO:0005515///protein binding+++GO:0030350///iron-responsive element binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0046872///metal ion binding+++GO:0001069///regulatory region RNA binding+++GO:0003994///aconitate hydratase activity+++GO:0003723///RNA binding+++GO:0030371///translation repressor activity+++GO:0051536///iron-sulfur cluster binding","GO:0006782///protoporphyrinogen IX biosynthetic process+++GO:0009791///post-embryonic development+++GO:0071287///cellular response to manganese ion+++GO:0046688///response to copper ion+++GO:0032526///response to retinoic acid+++GO:0006826///iron ion transport+++GO:0007420///brain development+++GO:0017148///negative regulation of translation+++GO:0010041///response to iron(III) ion+++GO:0010040///response to iron(II) ion+++GO:0034101///erythrocyte homeostasis+++GO:1904373///response to kainic acid+++GO:0030316///osteoclast differentiation+++GO:0071300///cellular response to retinoic acid+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0006879///cellular iron ion homeostasis+++GO:0072705///cellular response to mercaptoethanol+++GO:0007568///aging+++GO:1990910///response to hypobaric hypoxia+++GO:0014823///response to activity+++GO:0006099///tricarboxylic acid cycle+++GO:0010043///response to zinc ion+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0006417///regulation of translation+++GO:0006101///citrate metabolic process+++GO:0071456///cellular response to hypoxia+++GO:0014732///skeletal muscle atrophy+++GO:0071283///cellular response to iron(III) ion","iron responsive element binding protein 2","[IREB2_HUMAN|Reviewed]RecName: Full=Iron-responsive element-binding protein 2; Short=IRE-BP 2; AltName: Full=Iron regulatory protein 2; Short=IRP2;+++[D3DW85_HUMAN|Unreviewed]SubName: Full=Iron-responsive element binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW99170.1};+++[H0YL48_HUMAN|Unreviewed]SubName: Full=Iron-responsive element-binding protein 2 {ECO:0000313|Ensembl:ENSP00000453058};+++[H0YLE0_HUMAN|Unreviewed]SubName: Full=Iron-responsive element-binding protein 2 {ECO:0000313|Ensembl:ENSP00000453172}; Flags: Fragment;+++[H0YMA8_HUMAN|Unreviewed]SubName: Full=Iron-responsive element-binding protein 2 {ECO:0000313|Ensembl:ENSP00000453532};+++[H0YN46_HUMAN|Unreviewed]SubName: Full=Iron-responsive element-binding protein 2 {ECO:0000313|Ensembl:ENSP00000453863}; Flags: Fragment;+++[H0YNL8_HUMAN|Unreviewed]SubName: Full=Iron-responsive element-binding protein 2 {ECO:0000313|Ensembl:ENSP00000454063};"]
[3682,"'ITGAE'",73,65,77,71.6666666666667,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0008305///integrin complex+++GO:0016021///integral component of membrane+++GO:0009897///external side of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0007229///integrin-mediated signaling pathway","integrin subunit alpha E","[ITAE_HUMAN|Reviewed]RecName: Full=Integrin alpha-E; AltName: Full=HML-1 antigen; AltName: Full=Integrin alpha-IEL; AltName: Full=Mucosal lymphocyte 1 antigen; AltName: CD_antigen=CD103; Contains: RecName: Full=Integrin alpha-E light chain; Contains: RecName: Full=Integrin alpha-E heavy chain; Flags: Precursor;+++[K7EQU0_HUMAN|Unreviewed]SubName: Full=Integrin alpha-E {ECO:0000313|Ensembl:ENSP00000467977}; Flags: Fragment;"]
[3692,"'EIF6'",1344,1495,1322,1387,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005874///microtubule+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0071540///eukaryotic translation initiation factor 3 complex, eIF3e+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0043614///multi-eIF complex+++GO:0005634///nucleus+++GO:0014069///postsynaptic density+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0005829///cytosol+++GO:0030687///preribosome, large subunit precursor+++GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0005198///structural molecule activity+++GO:0043022///ribosome binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0043023///ribosomal large subunit binding+++GO:0003743///translation initiation factor activity","GO:0042304///regulation of fatty acid biosynthetic process+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0035278///miRNA mediated inhibition of translation+++GO:0042273///ribosomal large subunit biogenesis+++GO:0042254///ribosome biogenesis+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0042256///mature ribosome assembly+++GO:1902626///assembly of large subunit precursor of preribosome+++GO:0000054///ribosomal subunit export from nucleus+++GO:0035195///gene silencing by miRNA+++GO:0002183///cytoplasmic translational initiation+++GO:0032868///response to insulin+++GO:0045727///positive regulation of translation+++GO:0075522///IRES-dependent viral translational initiation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0075525///viral translational termination-reinitiation+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:0006110///regulation of glycolytic process+++GO:0002188///translation reinitiation","eukaryotic translation initiation factor 6","[IF6_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_03132}; Short=eIF-6 {ECO:0000255|HAMAP-Rule:MF_03132}; AltName: Full=B(2)GCN homolog; AltName: Full=B4 integrin interactor; AltName: Full=CAB; AltName: Full=p27(BBP);+++[A0A0B4J1Y7_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 6 {ECO:0000313|Ensembl:ENSP00000411450};+++[B7ZBH1_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 6 {ECO:0000313|Ensembl:ENSP00000390897}; Flags: Fragment;+++[F8WD20_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 6 {ECO:0000313|Ensembl:ENSP00000395907};+++[F8WDS6_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 6 {ECO:0000313|Ensembl:ENSP00000415044};"]
[372,"'ARCN1'",3690,3181,3292,3387.66666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0030137///COPI-coated vesicle+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0030133///transport vesicle+++GO:0030126///COPI vesicle coat+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0030663///COPI-coated vesicle membrane","GO:0003723///RNA binding","GO:0008344///adult locomotory behavior+++GO:0043473///pigmentation+++GO:0048193///Golgi vesicle transport+++GO:0015031///protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006886///intracellular protein transport+++GO:0021691///cerebellar Purkinje cell layer maturation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0051645///Golgi localization","archain 1","[COPD_HUMAN|Reviewed]RecName: Full=Coatomer subunit delta; AltName: Full=Archain; AltName: Full=Delta-coat protein; Short=Delta-COP;+++[B0YIW5_HUMAN|Unreviewed]RecName: Full=Coatomer subunit delta {ECO:0000256|RuleBase:RU364018};+++[B0YIW6_HUMAN|Unreviewed]SubName: Full=Archain 1, isoform CRA_a {ECO:0000313|EMBL:EAW67397.1}; SubName: Full=Coatomer subunit delta variant 2 {ECO:0000313|EMBL:ACA05944.1};+++[E9PK34_HUMAN|Unreviewed]RecName: Full=Coatomer subunit delta {ECO:0000256|RuleBase:RU364018};+++[Q6P1Q5_HUMAN|Unreviewed]RecName: Full=Coatomer subunit delta {ECO:0000256|RuleBase:RU364018};"]
[373156,"'GSTK1'",1343,1401,1504,1416,"00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++00480///Glutathione metabolism+++04146///Peroxisome+++05204///Chemical carcinogenesis",null,null,"R09409///glutathione-S-transferase   Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH+++R07091///S-(2,2-dichloro-1-hydroxy)ethyl-glutathione 2,2-dichloroacetaldehyde-lyase (glutathione-forming)   2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione+++R07092///1,1-dichloroethylene-epoxide:glutathione S-(chloroepoxyethyl)transferase [2-(S-glutathionyl)acetyl-chloride-forming]   1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid+++R07069///3,4-dihydro-3-hydroxy-4-S-glutathionyl bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene+++R07113///1,2-dibromoethane:glutathione ethylenetransferase (episulfonium-forming)   1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid+++R03522///RX:glutathione R-transferase   RX + Glutathione <=> Halide + R-S-Glutathione+++R07070///2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene+++R07093///chloroacetyl-chloride:glutathione S-chloroacetyltransferase   Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid+++R08280///4-glutathionyl cyclophosphamide hydrolase   Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O+++R07094///2-(S-glutathionyl)acetyl-chloride:glutathione 2-(S-glutathionyl)acetyltransferase   2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid+++R07026///1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene+++R07002///(1R)-hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene+++R07084///7,8-dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene hydrolase   Benzo[a]pyrene-7,8-diol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O+++R07025///1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene+++R07083///4,5-dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene glutathione-lyase (epoxide-forming)   Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene+++R07100///trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase   Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid+++R07004///(1S)-hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene+++R07116///2-bromoacetaldehyde:glutathione S-(formylmethyl)transferase   2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid+++R07024///1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene+++R07023///1-nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene+++R07003///(1R)-glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene","GO:0005739///mitochondrion+++GO:0005782///peroxisomal matrix+++GO:0005759///mitochondrial matrix+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005777///peroxisome+++GO:0005622///intracellular+++GO:0005829///cytosol","GO:0005102///signaling receptor binding+++GO:0004602///glutathione peroxidase activity+++GO:0004364///glutathione transferase activity+++GO:0005515///protein binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0016740///transferase activity","GO:0055114///oxidation-reduction process+++GO:0006749///glutathione metabolic process+++GO:0006625///protein targeting to peroxisome+++GO:0098869///cellular oxidant detoxification+++GO:1901687///glutathione derivative biosynthetic process+++GO:0030855///epithelial cell differentiation","glutathione S-transferase kappa 1","[GSTK1_HUMAN|Reviewed]RecName: Full=Glutathione S-transferase kappa 1; EC=2.5.1.18; AltName: Full=GST 13-13; AltName: Full=GST class-kappa; AltName: Full=GSTK1-1; Short=hGSTK1; AltName: Full=Glutathione S-transferase subunit 13;+++[C9JNT3_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase kappa 1 {ECO:0000313|Ensembl:ENSP00000408341}; Flags: Fragment;+++[E9PFN5_HUMAN|Unreviewed]RecName: Full=Glutathione S-transferase kappa {ECO:0000256|PIRNR:PIRNR006386}; EC=2.5.1.18 {ECO:0000256|PIRNR:PIRNR006386};+++[Q2NLC8_HUMAN|Unreviewed]SubName: Full=GSTK1 protein {ECO:0000313|EMBL:AAI10601.1}; Flags: Fragment;+++[Q6FII1_HUMAN|Unreviewed]RecName: Full=Glutathione S-transferase kappa {ECO:0000256|PIRNR:PIRNR006386}; EC=2.5.1.18 {ECO:0000256|PIRNR:PIRNR006386};"]
[3741,"'KCNA5'",2,3,5,3.33333333333333,null,"H00731///Atrial fibrillation",null,null,"GO:0045121///membrane raft+++GO:0005901///caveola+++GO:0016021///integral component of membrane+++GO:0014704///intercalated disc+++GO:0046691///intracellular canaliculus+++GO:0016020///membrane+++GO:0034705///potassium channel complex+++GO:0005783///endoplasmic reticulum+++GO:0009986///cell surface+++GO:0030018///Z disc+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane","GO:0086089///voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization+++GO:0005515///protein binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0005267///potassium channel activity+++GO:0015271///outward rectifier potassium channel activity+++GO:0051393///alpha-actinin binding+++GO:0086087///voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization+++GO:0086090///voltage-gated potassium channel activity involved in SA node cell action potential repolarization+++GO:0097110///scaffold protein binding+++GO:0019901///protein kinase binding+++GO:0005102///signaling receptor binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005216///ion channel activity","GO:0098914///membrane repolarization during atrial cardiac muscle cell action potential+++GO:0060372///regulation of atrial cardiac muscle cell membrane repolarization+++GO:0042391///regulation of membrane potential+++GO:0010033///response to organic substance+++GO:0019229///regulation of vasoconstriction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0071805///potassium ion transmembrane transport+++GO:0060081///membrane hyperpolarization+++GO:0006811///ion transport+++GO:0055093///response to hyperoxia+++GO:0051259///protein complex oligomerization+++GO:0042542///response to hydrogen peroxide+++GO:0001666///response to hypoxia+++GO:0051481///negative regulation of cytosolic calcium ion concentration+++GO:0050796///regulation of insulin secretion+++GO:0086052///membrane repolarization during SA node cell action potential+++GO:0051260///protein homooligomerization+++GO:0009612///response to mechanical stimulus+++GO:0086050///membrane repolarization during bundle of His cell action potential+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0043266///regulation of potassium ion transport+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:0097623///potassium ion export across plasma membrane+++GO:0007219///Notch signaling pathway+++GO:0034765///regulation of ion transmembrane transport+++GO:0055075///potassium ion homeostasis+++GO:2000288///positive regulation of myoblast proliferation+++GO:0006813///potassium ion transport+++GO:0055085///transmembrane transport","potassium voltage-gated channel subfamily A member 5","[KCNA5_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily A member 5; AltName: Full=HPCN1; AltName: Full=Voltage-gated potassium channel HK2; AltName: Full=Voltage-gated potassium channel subunit Kv1.5;"]
[374819,"'LRRC37A3'",259.22,194.68,218.52,224.14,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"leucine rich repeat containing 37 member A3","[L37A3_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 37A3; Flags: Precursor;+++[A0JLV1_HUMAN|Unreviewed]SubName: Full=LRRC37A3 protein {ECO:0000313|EMBL:AAI13644.1}; Flags: Fragment;+++[B4DSF2_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A3 {ECO:0000313|Ensembl:ENSP00000383674}; SubName: Full=cDNA FLJ56239, highly similar to Leucine-rich repeat-containing protein 37A {ECO:0000313|EMBL:BAG61614.1};+++[F8W7X0_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A3 {ECO:0000313|Ensembl:ENSP00000335617};+++[J3KT91_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A3 {ECO:0000313|Ensembl:ENSP00000462864}; Flags: Fragment;+++[J3KT96_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A3 {ECO:0000313|Ensembl:ENSP00000462872}; Flags: Fragment;+++[J3QKQ2_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A3 {ECO:0000313|Ensembl:ENSP00000463186}; Flags: Fragment;+++[J3QL27_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A3 {ECO:0000313|Ensembl:ENSP00000463346}; Flags: Fragment;+++[J3QTJ5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A3 {ECO:0000313|Ensembl:ENSP00000344298};"]
[374899,"'ZNF829'",56,58.03,52.85,55.6266666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 829","[ZN829_HUMAN|Reviewed]RecName: Full=Zinc finger protein 829;"]
[375189,"'PFN4'",4,3,5,4,"05132///Salmonella infection+++04015///Rap1 signaling pathway+++04810///Regulation of actin cytoskeleton+++04013///MAPK signaling pathway - fly+++05131///Shigellosis","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005938///cell cortex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0003785///actin monomer binding+++GO:0008289///lipid binding","GO:0042989///sequestering of actin monomers","profilin family member 4","[PROF4_HUMAN|Reviewed]RecName: Full=Profilin-4; AltName: Full=Profilin IV;+++[A0A1D5RMN8_HUMAN|Unreviewed]SubName: Full=Profilin-4 {ECO:0000313|Ensembl:ENSP00000393504}; Flags: Fragment;"]
[375444,"'C5orf34'",15,8,4,9,"03013///RNA transport+++04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"chromosome 5 open reading frame 34","[CE034_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf34;+++[E9PBC3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C5orf34 {ECO:0000313|Ensembl:ENSP00000424486}; Flags: Fragment;+++[H0YAD0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C5orf34 {ECO:0000313|Ensembl:ENSP00000426724}; Flags: Fragment;"]
[3759,"'KCNJ2'",125,103,91,106.333333333333,"04924///Renin secretion+++04921///Oxytocin signaling pathway+++04725///Cholinergic synapse+++04971///Gastric acid secretion","H00720///Long QT syndrome+++H00215///Periodic paralysis+++H00731///Atrial fibrillation+++H00725///Short QT syndrome+++H00748///Andersen-Tawil syndrome (ATS)",null,null,"GO:0014704///intercalated disc+++GO:0043025///neuronal cell body+++GO:0016021///integral component of membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0005794///Golgi apparatus+++GO:0031224///intrinsic component of membrane+++GO:0043197///dendritic spine+++GO:0030425///dendrite+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0030315///T-tubule","GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0042802///identical protein binding+++GO:0015467///G-protein activated inward rectifier potassium channel activity+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity","GO:0071260///cellular response to mechanical stimulus+++GO:0090076///relaxation of skeletal muscle+++GO:0015693///magnesium ion transport+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0030007///cellular potassium ion homeostasis+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0006811///ion transport+++GO:0060306///regulation of membrane repolarization+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086011///membrane repolarization during action potential+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:0055119///relaxation of cardiac muscle+++GO:0006813///potassium ion transport+++GO:0051289///protein homotetramerization+++GO:0034765///regulation of ion transmembrane transport+++GO:0086001///cardiac muscle cell action potential+++GO:0014861///regulation of skeletal muscle contraction via regulation of action potential+++GO:1990573///potassium ion import across plasma membrane+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0060075///regulation of resting membrane potential+++GO:0071805///potassium ion transmembrane transport","potassium voltage-gated channel subfamily J member 2","[KCNJ2_HUMAN|Reviewed]RecName: Full=Inward rectifier potassium channel 2; AltName: Full=Cardiac inward rectifier potassium channel; AltName: Full=Inward rectifier K(+) channel Kir2.1; Short=IRK-1; Short=hIRK1; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 2;"]
[377,"'ARF3'",4157,3876,4050.56,4027.85333333333,"04144///Endocytosis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity","GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","ADP ribosylation factor 3","[ARF3_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor 3;+++[A0A024R0Y6_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 3, isoform CRA_b {ECO:0000313|EMBL:EAW58027.1};+++[F5H0C7_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 3 {ECO:0000313|Ensembl:ENSP00000438063}; Flags: Fragment;+++[F5H1V1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 3 {ECO:0000313|Ensembl:ENSP00000446353}; Flags: Fragment;+++[F5H6T5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 3 {ECO:0000313|Ensembl:ENSP00000437374}; Flags: Fragment;"]
[3785,"'KCNQ2'",0,1,0,0.333333333333333,"04725///Cholinergic synapse","H00806///Benign familial neonatal and infantile epilepsies+++H00606///Early infantile epileptic encephalopathy",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0033268///node of Ranvier+++GO:0016021///integral component of membrane+++GO:0043194///axon initial segment+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex","GO:0005249///voltage-gated potassium channel activity+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0030506///ankyrin binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005516///calmodulin binding+++GO:0005515///protein binding","GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport+++GO:0007399///nervous system development+++GO:0071805///potassium ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0006811///ion transport+++GO:0006813///potassium ion transport","potassium voltage-gated channel subfamily Q member 2","[KCNQ2_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000305}; AltName: Full=KQT-like 2; AltName: Full=Neuroblastoma-specific potassium channel subunit alpha KvLQT2; AltName: Full=Voltage-gated potassium channel subunit Kv7.2;+++[A0A0D9SEV1_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486040};+++[A0A0D9SF10_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486194};+++[A0A0D9SFE0_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486509}; Flags: Fragment;+++[A0A0D9SG49_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487142};+++[A0A0D9SGD4_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487384}; Flags: Fragment;+++[A0A0D9SGG3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487469}; Flags: Fragment;+++[A0A0D9SGJ7_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487563}; Flags: Fragment;+++[A0A0G2JH35_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000349789}; Flags: Fragment;+++[A0A0G2JQC9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000485756}; Flags: Fragment;+++[A0A0G2JQG6_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000485832}; Flags: Fragment;+++[A0A0G2JR54_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486451}; Flags: Fragment;+++[A0A0G2JR60_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486464}; Flags: Fragment;+++[A0A0G2JR98_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486557}; Flags: Fragment;+++[A0A0G2JRN9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486949}; Flags: Fragment;+++[A0A0G2JRU6_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487078}; Flags: Fragment;+++[A0A0G2JS89_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487440}; Flags: Fragment;+++[A0A0G2JSD3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487545}; Flags: Fragment;+++[A0A1B0GUK1_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000490142}; Flags: Fragment;+++[A0A1B0GW14_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000490734};+++[H0UI91_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2, isoform CRA_j {ECO:0000313|EMBL:EAW75281.1};+++[Q4VXP6_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000359244};+++[Q53Y30_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2 {ECO:0000313|EMBL:AAP35692.1}; SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2, isoform CRA_e {ECO:0000313|EMBL:EAW75275.1};"]
[3798,"'KIF5A'",92,76,68,78.6666666666667,"04144///Endocytosis+++04728///Dopaminergic synapse","H01881///Complex cortical dysplasia with other brain malformations+++H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005856///cytoskeleton+++GO:0045202///synapse+++GO:0043025///neuronal cell body+++GO:0035253///ciliary rootlet+++GO:0005737///cytoplasm+++GO:1904115///axon cytoplasm+++GO:0032839///dendrite cytoplasm+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0043005///neuron projection","GO:0003777///microtubule motor activity+++GO:0019894///kinesin binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0008017///microtubule binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003774///motor activity","GO:0007018///microtubule-based movement+++GO:0007411///axon guidance+++GO:0048489///synaptic vesicle transport+++GO:1990049///retrograde neuronal dense core vesicle transport+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0099641///anterograde axonal protein transport+++GO:0007268///chemical synaptic transmission+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0098971///anterograde dendritic transport of neurotransmitter receptor complex+++GO:0016192///vesicle-mediated transport","kinesin family member 5A","[KIF5A_HUMAN|Reviewed]RecName: Full=Kinesin heavy chain isoform 5A; AltName: Full=Kinesin heavy chain neuron-specific 1; AltName: Full=Neuronal kinesin heavy chain; Short=NKHC;+++[A5D6Y6_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394}; Flags: Fragment;+++[J3KNA1_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};"]
[3836,"'KPNA1'",1107,894,902,967.666666666667,"05164///Influenza A",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005643///nuclear pore+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0005654///nucleoplasm+++GO:0014069///postsynaptic density+++GO:0043657///host cell","GO:0061608///nuclear import signal receptor activity+++GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0008565///protein transporter activity","GO:0075733///intracellular transport of virus+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0000018///regulation of DNA recombination+++GO:0006309///apoptotic DNA fragmentation+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0016032///viral process+++GO:0019054///modulation by virus of host process+++GO:0099527///postsynapse to nucleus signaling pathway","karyopherin subunit alpha 1","[IMA5_HUMAN|Reviewed]RecName: Full=Importin subunit alpha-5; AltName: Full=Karyopherin subunit alpha-1; AltName: Full=Nucleoprotein interactor 1; Short=NPI-1; AltName: Full=RAG cohort protein 2; AltName: Full=SRP1-beta; Contains: RecName: Full=Importin subunit alpha-5, N-terminally processed;+++[B3KXZ2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46417 fis, clone THYMU3012402, highly similar to Importin alpha-1 subunit {ECO:0000313|EMBL:BAG54654.1}; SubName: Full=cDNA FLJ55353, highly similar to Importin alpha-1 subunit {ECO:0000313|EMBL:BAG61106.1};+++[C9J352_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-5 {ECO:0000313|Ensembl:ENSP00000417319}; Flags: Fragment;+++[C9J4U1_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-5 {ECO:0000313|Ensembl:ENSP00000417166}; Flags: Fragment;+++[C9JWD9_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-5 {ECO:0000313|Ensembl:ENSP00000419257}; Flags: Fragment;+++[C9JYI4_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-5 {ECO:0000313|Ensembl:ENSP00000419890}; Flags: Fragment;+++[F2Z3G4_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-5 {ECO:0000313|Ensembl:ENSP00000418394};+++[L8EC94_HUMAN|Unreviewed]SubName: Full=Alternative protein KPNA1 {ECO:0000313|EMBL:CCQ43172.1};+++[Q5BKZ2_HUMAN|Unreviewed]RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};"]
[3857,"'KRT9'",5,5,1,3.66666666666667,"04915///Estrogen signaling pathway","H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H00667///Woolly hair+++H00738///Ichthyosis with confetti+++H00796///Dermatopathia pigmentosa reticularis+++H00726///Meesmann corneal dystrophy+++H01673///Palmoplantar keratoderma+++H00584///Epidermolysis bullosa simplex+++H00724///White sponge nevus+++H00723///Non-epidermolytic palmoplantar keratoderma (NEPPK)+++H00708///Naegeli-Franceschetti-Jadassohn syndrome+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00684///Pachyonychia congenita",null,null,"GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005882///intermediate filament","GO:0005198///structural molecule activity+++GO:0005200///structural constituent of cytoskeleton","GO:0031424///keratinization+++GO:0008544///epidermis development+++GO:0007283///spermatogenesis+++GO:0070268///cornification+++GO:0045109///intermediate filament organization+++GO:0043588///skin development","keratin 9","[K1C9_HUMAN|Reviewed]RecName: Full=Keratin, type I cytoskeletal 9; AltName: Full=Cytokeratin-9; Short=CK-9; AltName: Full=Keratin-9; Short=K9;+++[K7EQQ3_HUMAN|Unreviewed]SubName: Full=Keratin, type I cytoskeletal 9 {ECO:0000313|Ensembl:ENSP00000467932};"]
[387263,"'C6orf120'",567,431,529,509,"05225///Hepatocellular carcinoma",{"$nulls":3},"GO:0035578///azurophil granule lumen+++GO:0005576///extracellular region","GO:0046872///metal ion binding","GO:0006915///apoptotic process+++GO:0043312///neutrophil degranulation","chromosome 6 open reading frame 120","[CF120_HUMAN|Reviewed]RecName: Full=UPF0669 protein C6orf120; Flags: Precursor;+++[B4DJ79_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55847 {ECO:0000313|EMBL:BAG58741.1};"]
[387763,"'C11orf96'",9,11,13,11,{"$nulls":7},"chromosome 11 open reading frame 96","[CK096_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf96; AltName: Full=Protein Ag2 homolog;+++[A0A087WW59_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf96 {ECO:0000313|Ensembl:ENSP00000479976};+++[E9PKL4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf96 {ECO:0000313|Ensembl:ENSP00000431597};"]
[388112,"'NANOGP8'",3.33,0,1.08,1.47,"04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer",{"$nulls":3},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003674///molecular_function+++GO:0043565///sequence-specific DNA binding","GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:0008284///positive regulation of cell proliferation+++GO:0006355///regulation of transcription, DNA-templated","Nanog homeobox retrogene P8","[NANP8_HUMAN|Reviewed]RecName: Full=Homeobox protein NANOGP8;+++[A0A0D9SG05_HUMAN|Unreviewed]SubName: Full=Homeobox protein NANOGP8 {ECO:0000313|Ensembl:ENSP00000487045};+++[J7H427_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90912.1}; Flags: Fragment;+++[J7H466_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90934.1}; Flags: Fragment;+++[J7H7A5_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90941.1}; Flags: Fragment;+++[J7H7C4_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90961.1}; Flags: Fragment;+++[J7H9Z3_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90938.1}; Flags: Fragment;+++[J7HA13_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90958.1}; Flags: Fragment;+++[J7HAY6_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90885.1}; Flags: Fragment;+++[J7HAZ5_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90900.1}; Flags: Fragment;+++[J7HB24_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90940.1}; Flags: Fragment;"]
[388389,"'CCDC103'",65,63,41,56.3333333333333,"03040///Spliceosome","H01838///Mandibulofacial dysostosis with microcephaly","M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005930///axoneme","GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0001947///heart looping+++GO:0071907///determination of digestive tract left/right asymmetry+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry+++GO:0070286///axonemal dynein complex assembly+++GO:0036158///outer dynein arm assembly+++GO:0030030///cell projection organization+++GO:0036159///inner dynein arm assembly+++GO:0003341///cilium movement","coiled-coil domain containing 103","[CC103_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 103;+++[F8W6J8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 103 {ECO:0000313|Ensembl:ENSP00000350420}; Flags: Fragment;+++[J3KSE5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 103 {ECO:0000313|Ensembl:ENSP00000462450}; Flags: Fragment;"]
[388561,"'ZNF761'",90.7,88.24,102.88,93.94,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 761","[ZN761_HUMAN|Reviewed]RecName: Full=Zinc finger protein 761;+++[A0A087WXU7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 761 {ECO:0000313|Ensembl:ENSP00000481316};+++[A0A087WYY7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 761 {ECO:0000313|Ensembl:ENSP00000482214}; Flags: Fragment;+++[A0A0A0MS71_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 468 {ECO:0000313|Ensembl:ENSP00000379690};+++[M0QYC0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 468 {ECO:0000313|Ensembl:ENSP00000469733};+++[M0QYE7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 468 {ECO:0000313|Ensembl:ENSP00000469779}; Flags: Fragment;+++[M0QZR5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 468 {ECO:0000313|Ensembl:ENSP00000470717}; Flags: Fragment;+++[M0R171_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 468 {ECO:0000313|Ensembl:ENSP00000471675};+++[Q6IQ01_HUMAN|Unreviewed]SubName: Full=ZNF761 protein {ECO:0000313|EMBL:AAH71639.1}; SubName: Full=Zinc finger protein 761 {ECO:0000313|Ensembl:ENSP00000481271};+++[Q6P514_HUMAN|Unreviewed]SubName: Full=ZNF468 protein {ECO:0000313|EMBL:AAH63143.1};"]
[388662,"'SLC6A17'",1712,1605,1402,1573,null,"H01304///Hyperglycinuria+++H01911///Syndromic autosomal recessive mental retardation+++H00905///Iminoglycinuria",null,null,"GO:0030054///cell junction+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005887///integral component of plasma membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030672///synaptic vesicle membrane+++GO:0098978///glutamatergic synapse+++GO:0098982///GABA-ergic synapse+++GO:0016020///membrane","GO:0005328///neurotransmitter:sodium symporter activity+++GO:0015293///symporter activity","GO:0015804///neutral amino acid transport+++GO:0015824///proline transport+++GO:0032328///alanine transport+++GO:0015820///leucine transport+++GO:0006836///neurotransmitter transport+++GO:0055085///transmembrane transport+++GO:0007420///brain development+++GO:0015816///glycine transport","solute carrier family 6 member 17","[S6A17_HUMAN|Reviewed]RecName: Full=Sodium-dependent neutral amino acid transporter SLC6A17; AltName: Full=Sodium-dependent neurotransmitter transporter NTT4; AltName: Full=Solute carrier family 6 member 17;+++[L8E704_HUMAN|Unreviewed]SubName: Full=Alternative protein SLC6A17 {ECO:0000313|EMBL:CCQ43025.1};"]
[388698,"'FLG2'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0001533///cornified envelope+++GO:0005634///nucleus+++GO:0036457///keratohyalin granule+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:1904724///tertiary granule lumen","GO:0030280///structural constituent of epidermis+++GO:0046914///transition metal ion binding+++GO:0005198///structural molecule activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0061436///establishment of skin barrier+++GO:0043312///neutrophil degranulation","filaggrin family member 2","[FILA2_HUMAN|Reviewed]RecName: Full=Filaggrin-2; Short=FLG-2; AltName: Full=Intermediate filament-associated and psoriasis-susceptibility protein; Short=Ifapsoriasin;+++[L8E7D3_HUMAN|Unreviewed]SubName: Full=Alternative protein FLG2 {ECO:0000313|EMBL:CCQ43039.1};"]
[389125,"'MUSTN1'",2.15,7.11,0,3.08666666666667,{"$nulls":4},"GO:0005634///nucleus",null,"GO:0042246///tissue regeneration+++GO:0002062///chondrocyte differentiation+++GO:0035988///chondrocyte proliferation","musculoskeletal, embryonic nuclear protein 1","[MSTN1_HUMAN|Reviewed]RecName: Full=Musculoskeletal embryonic nuclear protein 1;+++[C9JYJ2_HUMAN|Unreviewed]SubName: Full=Musculoskeletal embryonic nuclear protein 1 {ECO:0000313|Ensembl:ENSP00000419877};"]
[389197,"'C4orf50'",136,87,94,105.666666666667,{"$nulls":7},"chromosome 4 open reading frame 50","[CD050_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C4orf50;+++[A0A1W2PRI9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C4orf50 {ECO:0000313|Ensembl:ENSP00000492340}; Flags: Fragment;+++[E9PNW5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C4orf50 {ECO:0000313|Ensembl:ENSP00000437121};"]
[389692,"'MAFA'",21,14,22,19,"04950///Maturity onset diabetes of the young+++04930///Type II diabetes mellitus",{"$nulls":3},"GO:0005634///nucleus","GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0007263///nitric oxide mediated signal transduction+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030073///insulin secretion+++GO:0009749///response to glucose","MAF bZIP transcription factor A","[MAFA_HUMAN|Reviewed]RecName: Full=Transcription factor MafA; AltName: Full=Pancreatic beta-cell-specific transcriptional activator; AltName: Full=RIPE3b1 factor {ECO:0000303|PubMed:12011435}; AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog A;+++[D4Q8H3_HUMAN|Unreviewed]SubName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog A {ECO:0000313|EMBL:BAJ04327.1};"]
[3898,"'LAD1'",20,13,23,18.6666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005604///basement membrane+++GO:0005576///extracellular region+++GO:0015629///actin cytoskeleton","GO:0005198///structural molecule activity+++GO:0045296///cadherin binding",null,"ladinin 1","[LAD1_HUMAN|Reviewed]RecName: Full=Ladinin-1; Short=Lad-1; AltName: Full=Linear IgA disease antigen; Short=LADA;+++[A0A0J9YVY2_HUMAN|Unreviewed]SubName: Full=Ladinin-1 {ECO:0000313|Ensembl:ENSP00000487726}; Flags: Fragment;+++[A0A0J9YW63_HUMAN|Unreviewed]SubName: Full=Ladinin-1 {ECO:0000313|Ensembl:ENSP00000487828}; Flags: Fragment;+++[A0A0J9YYF6_HUMAN|Unreviewed]SubName: Full=Ladinin-1 {ECO:0000313|Ensembl:ENSP00000488829}; Flags: Fragment;+++[E9PDI4_HUMAN|Unreviewed]RecName: Full=Ladinin-1 {ECO:0000256|PIRNR:PIRNR038144}; Short=Lad-1 {ECO:0000256|PIRNR:PIRNR038144};+++[H0Y901_HUMAN|Unreviewed]SubName: Full=Ladinin-1 {ECO:0000313|Ensembl:ENSP00000422687}; Flags: Fragment;+++[Q6IPJ9_HUMAN|Unreviewed]RecName: Full=Ladinin-1 {ECO:0000256|PIRNR:PIRNR038144}; Short=Lad-1 {ECO:0000256|PIRNR:PIRNR038144};"]
[3908,"'LAMA2'",253,209,246,236,"05165///Human papillomavirus infection+++05146///Amoebiasis+++04510///Focal adhesion+++05222///Small cell lung cancer+++05200///Pathways in cancer+++05145///Toxoplasmosis+++04512///ECM-receptor interaction+++04151///PI3K-Akt signaling pathway","H01958///Merosin-deficient congenital muscular dystrophy+++H00590///Congenital muscular dystrophies (CMD/MDC)","M00679///BMP signaling",null,"GO:0005604///basement membrane+++GO:0042383///sarcolemma+++GO:0043083///synaptic cleft+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:0043197///dendritic spine+++GO:0031594///neuromuscular junction","GO:0005201///extracellular matrix structural constituent+++GO:0005198///structural molecule activity+++GO:0005102///signaling receptor binding","GO:0045995///regulation of embryonic development+++GO:0007411///axon guidance+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0007517///muscle organ development+++GO:0014037///Schwann cell differentiation+++GO:0030198///extracellular matrix organization+++GO:0030334///regulation of cell migration+++GO:0030155///regulation of cell adhesion+++GO:0007155///cell adhesion","laminin subunit alpha 2","[LAMA2_HUMAN|Reviewed]RecName: Full=Laminin subunit alpha-2; AltName: Full=Laminin M chain; AltName: Full=Laminin-12 subunit alpha; AltName: Full=Laminin-2 subunit alpha; AltName: Full=Laminin-4 subunit alpha; AltName: Full=Merosin heavy chain; Flags: Precursor;+++[A0A087WX80_HUMAN|Unreviewed]SubName: Full=Laminin subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000480802};+++[A0A087WYF1_HUMAN|Unreviewed]SubName: Full=Laminin subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000481744};+++[A0A1P8NQA0_HUMAN|Unreviewed]SubName: Full=Mutant laminin subunit alpha 2 {ECO:0000313|EMBL:APX42425.1}; Flags: Fragment;+++[A0A1P8NQC0_HUMAN|Unreviewed]SubName: Full=Laminin subunit alpha-2 splice variant {ECO:0000313|EMBL:APX42440.1}; Flags: Fragment;+++[A0A1P8NQC4_HUMAN|Unreviewed]SubName: Full=Laminin subunit alpha-2 splice variant {ECO:0000313|EMBL:APX42441.1}; Flags: Fragment;+++[A0A2R8YDM5_HUMAN|Unreviewed]SubName: Full=Laminin subunit alpha-2 {ECO:0000313|Ensembl:ENSP00000493888}; Flags: Fragment;+++[Q59H37_HUMAN|Unreviewed]SubName: Full=Laminin alpha 2 subunit variant {ECO:0000313|EMBL:BAD92159.1}; Flags: Fragment;"]
[391,"'RHOG'",570,610,531,570.333333333333,"05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++05131///Shigellosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030667///secretory granule membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005938///cell cortex","GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding","GO:0043312///neutrophil degranulation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1900027///regulation of ruffle assembly+++GO:0016601///Rac protein signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0060326///cell chemotaxis+++GO:0008284///positive regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0046854///phosphatidylinositol phosphorylation+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0007266///Rho protein signal transduction+++GO:0090630///activation of GTPase activity","ras homolog family member G","[RHOG_HUMAN|Reviewed]RecName: Full=Rho-related GTP-binding protein RhoG; Flags: Precursor;+++[Q6ICQ8_HUMAN|Unreviewed]SubName: Full=ARHG protein {ECO:0000313|EMBL:CAG29331.1}; SubName: Full=Ras homolog gene family, member G (Rho G) {ECO:0000313|EMBL:AAI04178.1}; SubName: Full=Ras homolog gene family, member G (Rho G), isoform CRA_a {ECO:0000313|EMBL:EAX02575.1}; Flags: Fragment;"]
[391322,"'LOC391322'",10,15,11,12,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0016829///lyase activity",null,"D-dopachrome tautomerase-like","[A0A0F7RQT4_HUMAN|Unreviewed]SubName: Full=D-dopachrome tautomerase 3 {ECO:0000313|EMBL:CCP37993.1};"]
[3939,"'LDHA'",9931,10206,9610,9915.66666666667,"00620///Pyruvate metabolism+++00270///Cysteine and methionine metabolism+++01130///Biosynthesis of antibiotics+++04922///Glucagon signaling pathway+++00640///Propanoate metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++01120///Microbial metabolism in diverse environments+++00010///Glycolysis / Gluconeogenesis","H01946///Glycogen storage disease type XI+++H01762///Muscle glycogen storage disease+++H00069///Glycogen storage diseases (GSD)",null,"R01000///2-hydroxybutyrate:NAD+ oxidoreductase   2-Hydroxybutanoic acid + NAD+ <=> 2-Oxobutanoate + NADH + H++++R03104///3-Mercaptolactate:NAD+ oxidoreductase   3-Mercaptolactate + NAD+ <=> Mercaptopyruvate + NADH + H++++R00703///(S)-Lactate:NAD+ oxidoreductase   (S)-Lactate + NAD+ <=> Pyruvate + NADH + H+","GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0019900///kinase binding+++GO:0003824///catalytic activity+++GO:0004459///L-lactate dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0004457///lactate dehydrogenase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016491///oxidoreductase activity+++GO:0051287///NAD binding+++GO:0045296///cadherin binding","GO:0006090///pyruvate metabolic process+++GO:0001666///response to hypoxia+++GO:0019674///NAD metabolic process+++GO:0007584///response to nutrient+++GO:0055114///oxidation-reduction process+++GO:0051591///response to cAMP+++GO:0042493///response to drug+++GO:0019752///carboxylic acid metabolic process+++GO:0006089///lactate metabolic process+++GO:0043627///response to estrogen+++GO:0048569///post-embryonic animal organ development+++GO:0021762///substantia nigra development+++GO:0043065///positive regulation of apoptotic process+++GO:0005975///carbohydrate metabolic process+++GO:0006096///glycolytic process+++GO:0042542///response to hydrogen peroxide+++GO:0014070///response to organic cyclic compound+++GO:0009749///response to glucose","lactate dehydrogenase A","[LDHA_HUMAN|Reviewed]RecName: Full=L-lactate dehydrogenase A chain; Short=LDH-A; EC=1.1.1.27; AltName: Full=Cell proliferation-inducing gene 19 protein; AltName: Full=LDH muscle subunit; Short=LDH-M; AltName: Full=Renal carcinoma antigen NY-REN-59;+++[F5GWW2_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000441699};+++[F5GXC7_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000441058};+++[F5GXH2_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000446415}; Flags: Fragment;+++[F5GXU1_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000440368};+++[F5GXY2_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000440161}; Flags: Fragment;+++[F5GYU2_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000441241}; Flags: Fragment;+++[F5GZQ4_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000444292}; Flags: Fragment;+++[F5H5J4_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000443362};+++[F5H6W8_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000442979};+++[F5H8H6_HUMAN|Unreviewed]SubName: Full=L-lactate dehydrogenase A chain {ECO:0000313|Ensembl:ENSP00000443545};+++[V9HWB9_HUMAN|Unreviewed]RecName: Full=L-lactate dehydrogenase {ECO:0000256|RuleBase:RU000496}; EC=1.1.1.27 {ECO:0000256|RuleBase:RU000496};"]
[3956,"'LGALS1'",6184,7188,4946,6106,"00750///Vitamin B6 metabolism+++01100///Metabolic pathways",null,null,"R02494///pyridoxamine-5'-phosphate phosphohydrolase Pyridoxamine + Orthophosphate <=> Pyridoxamine phosphate + H2O+++R00173///pyridoxal-5'-phosphate phosphohydrolase Pyridoxal phosphate + H2O <=> Pyridoxal + Orthophosphate+++R01911///pyridoxine-5'-phosphate phosphohydrolase Pyridoxine + Orthophosphate <=> Pyridoxine phosphate + H2O","GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0062023///collagen-containing extracellular matrix+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005622///intracellular","GO:0043236///laminin binding+++GO:0003723///RNA binding+++GO:0030246///carbohydrate binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0030395///lactose binding","GO:0010977///negative regulation of neuron projection development+++GO:0045445///myoblast differentiation+++GO:2001200///positive regulation of dendritic cell differentiation+++GO:0044267///cellular protein metabolic process+++GO:0071333///cellular response to glucose stimulus+++GO:0043687///post-translational protein modification+++GO:0006915///apoptotic process+++GO:0031295///T cell costimulation+++GO:0035900///response to isolation stress+++GO:0034120///positive regulation of erythrocyte aggregation+++GO:0048678///response to axon injury+++GO:0042493///response to drug+++GO:0071407///cellular response to organic cyclic compound+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0046598///positive regulation of viral entry into host cell+++GO:0002317///plasma cell differentiation","galectin 1","[LEG1_HUMAN|Reviewed]RecName: Full=Galectin-1; Short=Gal-1; AltName: Full=14 kDa laminin-binding protein; Short=HLBP14; AltName: Full=14 kDa lectin; AltName: Full=Beta-galactoside-binding lectin L-14-I; AltName: Full=Galaptin; AltName: Full=HBL; AltName: Full=HPL; AltName: Full=Lactose-binding lectin 1; AltName: Full=Lectin galactoside-binding soluble 1; AltName: Full=Putative MAPK-activating protein PM12; AltName: Full=S-Lac lectin 1;+++[A0A0B6XK00_HUMAN|Unreviewed]SubName: Full=Lectin, galactoside-binding, soluble, 1 {ECO:0000313|EMBL:CEF49527.1}; Flags: Fragment;+++[F8WCQ5_HUMAN|Unreviewed]SubName: Full=Galectin-1 {ECO:0000313|Ensembl:ENSP00000404414};+++[F8WEI7_HUMAN|Unreviewed]SubName: Full=Galectin-1 {ECO:0000313|Ensembl:ENSP00000388296};"]
[399473,"'SPRED3'",990,844,800,878,null,"H00523///Noonan syndrome and related disorders+++H01986///Legius syndrome",null,null,"GO:0016020///membrane",null,"GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction","sprouty related EVH1 domain containing 3","[SPRE3_HUMAN|Reviewed]RecName: Full=Sprouty-related, EVH1 domain-containing protein 3; Short=Spred-3;+++[B9EKV1_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain containing 3 {ECO:0000313|EMBL:AAI51137.1};+++[K7EKP4_HUMAN|Unreviewed]SubName: Full=HCG1647763 {ECO:0000313|EMBL:EAW56789.1}; SubName: Full=Sprouty-related, EVH1 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000465713};+++[K7EPT9_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000467532}; Flags: Fragment;+++[K7EPU5_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000467540};"]
[399668,"'SMIM10L2A'",112,94,152,119.333333333333,{"$nulls":7},"small integral membrane protein 10 like 2A","[SIL2A_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 2A {ECO:0000305};+++[SIL2B_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 2B {ECO:0000305};"]
[400499,"'LOC400499'",3,4,7,4.66666666666667,"04137///Mitophagy - animal+++04142///Lysosome+++04140///Autophagy - animal","H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0016021///integral component of membrane","GO:0005319///lipid transporter activity","GO:0006869///lipid transport","vitellogenin","[M0QZD8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000470478};+++[M0R1J3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000471908}; Flags: Fragment;+++[M0R2I5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000472593}; Flags: Fragment;+++[M0R2X1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000472859}; Flags: Fragment;"]
[400591,"'C17orf102'",0,1,0,0.333333333333333,{"$nulls":7},"chromosome 17 open reading frame 102","[CQ102_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf102;"]
[400950,"'C2orf91'",4,1.57,1,2.19,{"$nulls":7},"chromosome 2 open reading frame 91","[CB091_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C2orf91;+++[A0A087WVU8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf91 {ECO:0000313|Ensembl:ENSP00000479699};"]
[401137,"'PRR27'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region",null,null,"proline rich 27","[PRR27_HUMAN|Reviewed]RecName: Full=Proline-rich protein 27; Flags: Precursor;+++[D6RGD6_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 27 {ECO:0000313|Ensembl:ENSP00000421286};+++[H0Y8Q8_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 27 {ECO:0000313|Ensembl:ENSP00000421773}; Flags: Fragment;"]
[401474,"'SAMD12'",253,235,227,238.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination","sterile alpha motif domain containing 12","[SAM12_HUMAN|Reviewed]RecName: Full=Sterile alpha motif domain-containing protein 12; Short=SAM domain-containing protein 12;+++[B8ZZB7_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000387133};+++[E9PLP5_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000431360}; Flags: Fragment;+++[F8VYB8_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000387605};+++[H0Y632_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000402786}; Flags: Fragment;+++[H0YDQ2_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000434079}; Flags: Fragment;+++[H0YEJ0_HUMAN|Unreviewed]SubName: Full=Sterile alpha motif domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000435927}; Flags: Fragment;"]
[401612,"'SLC25A53'",26,17,18,20.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport","solute carrier family 25 member 53","[S2553_HUMAN|Reviewed]RecName: Full=Solute carrier family 25 member 53; AltName: Full=Mitochondrial carrier triple repeat protein 6;"]
[402682,"'UFSP1'",16,23,25,21.3333333333333,{"$nulls":5},"GO:0071567///UFM1 hydrolase activity+++GO:0003674///molecular_function+++GO:0008234///cysteine-type peptidase activity","GO:0006508///proteolysis+++GO:0008150///biological_process","UFM1 specific peptidase 1 (inactive)","[UFSP1_HUMAN|Reviewed]RecName: Full=Inactive Ufm1-specific protease 1; Short=UfSP1;"]
[404217,"'CTXN1'",3622,4499,3730,3950.33333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane","GO:0003700///DNA-binding transcription factor activity","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006383///transcription by RNA polymerase III+++GO:0009301///snRNA transcription","cortexin 1","[CTXN1_HUMAN|Reviewed]RecName: Full=Cortexin-1;"]
[4054,"'LTBP3'",30145,31981,28371,30165.6666666667,null,"H00625///Tooth agenesis+++H00904///Cutis laxa with severe pulmonary, gastrointestinal, and urinary abnormalities+++H01203///Primary congenital glaucoma (PCG)+++H00557///Cutis laxa",null,null,"GO:0031012///extracellular matrix+++GO:0062023///collagen-containing extracellular matrix+++GO:0005623///cell+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0008201///heparin binding+++GO:0005509///calcium ion binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0050431///transforming growth factor beta binding+++GO:0019838///growth factor binding","GO:0009306///protein secretion+++GO:0006605///protein targeting+++GO:2000741///positive regulation of mesenchymal stem cell differentiation+++GO:0097435///supramolecular fiber organization+++GO:0036363///transforming growth factor beta activation+++GO:1902462///positive regulation of mesenchymal stem cell proliferation+++GO:0007179///transforming growth factor beta receptor signaling pathway","latent transforming growth factor beta binding protein 3","[LTBP3_HUMAN|Reviewed]RecName: Full=Latent-transforming growth factor beta-binding protein 3; Short=LTBP-3; Flags: Precursor;+++[B9EG76_HUMAN|Unreviewed]SubName: Full=LTBP3 protein {ECO:0000313|EMBL:AAI36278.1}; SubName: Full=Latent transforming growth factor beta binding protein 3, isoform CRA_c {ECO:0000313|EMBL:EAW74403.1};+++[E9PJR2_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000435530};+++[E9PKW1_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000435276}; Flags: Fragment;+++[E9PPT7_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000436341}; Flags: Fragment;+++[E9PQR0_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000434406};+++[E9PR75_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000436032}; Flags: Fragment;+++[E9PR84_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000434315};+++[E9PRF2_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000432350};+++[G3V3X5_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 2 {ECO:0000313|Ensembl:ENSP00000451477};+++[G3V511_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 2 {ECO:0000313|Ensembl:ENSP00000452110};+++[H0YC99_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000431219}; Flags: Fragment;+++[H0YCQ2_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000432121}; Flags: Fragment;+++[H0YCX6_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000432476}; Flags: Fragment;+++[H0YE75_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 3 {ECO:0000313|Ensembl:ENSP00000435146}; Flags: Fragment;+++[H0YJ20_HUMAN|Unreviewed]SubName: Full=Latent-transforming growth factor beta-binding protein 2 {ECO:0000313|Ensembl:ENSP00000450668}; Flags: Fragment;+++[Q6AZ94_HUMAN|Unreviewed]SubName: Full=Latent transforming growth factor beta binding protein 2 {ECO:0000313|EMBL:AAH78659.1};+++[Q8WYU6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein pp6425 {ECO:0000313|EMBL:AAL55861.1};"]
[4072,"'EPCAM'",11,15,20,15.3333333333333,null,"H01174///Congenital diarrhea+++H00876///Mismatch repair deficiency",null,null,"GO:0016324///apical plasma membrane+++GO:0005923///bicellular tight junction+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0016323///basolateral plasma membrane","GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0098641///cadherin binding involved in cell-cell adhesion","GO:2000648///positive regulation of stem cell proliferation+++GO:0098609///cell-cell adhesion+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0050900///leukocyte migration+++GO:0001657///ureteric bud development+++GO:0008284///positive regulation of cell proliferation+++GO:0048863///stem cell differentiation+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin","epithelial cell adhesion molecule","[EPCAM_HUMAN|Reviewed]RecName: Full=Epithelial cell adhesion molecule; Short=Ep-CAM; AltName: Full=Adenocarcinoma-associated antigen; AltName: Full=Cell surface glycoprotein Trop-1; AltName: Full=Epithelial cell surface antigen; AltName: Full=Epithelial glycoprotein; Short=EGP; AltName: Full=Epithelial glycoprotein 314; Short=EGP314; Short=hEGP314; AltName: Full=KS 1/4 antigen; AltName: Full=KSA; AltName: Full=Major gastrointestinal tumor-associated protein GA733-2; AltName: Full=Tumor-associated calcium signal transducer 1; AltName: CD_antigen=CD326; Flags: Precursor;+++[B5MCA4_HUMAN|Unreviewed]SubName: Full=Epithelial cell adhesion molecule {ECO:0000313|Ensembl:ENSP00000385476};+++[C9JKY3_HUMAN|Unreviewed]SubName: Full=Epithelial cell adhesion molecule {ECO:0000313|Ensembl:ENSP00000389028}; Flags: Fragment;"]
[4090,"'SMAD5'",540,302,367,403,"04550///Signaling pathways regulating pluripotency of stem cells+++04350///TGF-beta signaling pathway",null,"M00679///BMP signaling",null,"GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005622///intracellular+++GO:0005667///transcription factor complex+++GO:0071141///SMAD protein complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0030618///transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0002051///osteoblast fate commitment+++GO:0007165///signal transduction+++GO:0030218///erythrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001503///ossification+++GO:0071407///cellular response to organic cyclic compound+++GO:0006468///protein phosphorylation+++GO:0001880///Mullerian duct regression+++GO:0045669///positive regulation of osteoblast differentiation+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030509///BMP signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0071773///cellular response to BMP stimulus+++GO:0060348///bone development+++GO:0051216///cartilage development+++GO:0060395///SMAD protein signal transduction+++GO:0007281///germ cell development+++GO:0001657///ureteric bud development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0009880///embryonic pattern specification+++GO:0060048///cardiac muscle contraction","SMAD family member 5","[SMAD5_HUMAN|Reviewed]RecName: Full=Mothers against decapentaplegic homolog 5; Short=MAD homolog 5; Short=Mothers against DPP homolog 5; AltName: Full=JV5-1; AltName: Full=SMAD family member 5; Short=SMAD 5; Short=Smad5; Short=hSmad5;+++[D6R9D4_HUMAN|Unreviewed]SubName: Full=Mothers against decapentaplegic homolog 5 {ECO:0000313|Ensembl:ENSP00000422954}; Flags: Fragment;+++[D6RBB4_HUMAN|Unreviewed]SubName: Full=Mothers against decapentaplegic homolog 5 {ECO:0000313|Ensembl:ENSP00000424279}; Flags: Fragment;+++[D6RIZ9_HUMAN|Unreviewed]SubName: Full=Mothers against decapentaplegic homolog 5 {ECO:0000313|Ensembl:ENSP00000425749}; Flags: Fragment;+++[H0YAK7_HUMAN|Unreviewed]SubName: Full=Mothers against decapentaplegic homolog 5 {ECO:0000313|Ensembl:ENSP00000427474}; Flags: Fragment;+++[H0YAM3_HUMAN|Unreviewed]SubName: Full=Mothers against decapentaplegic homolog 5 {ECO:0000313|Ensembl:ENSP00000427650}; Flags: Fragment;+++[Q68DB7_HUMAN|Unreviewed]RecName: Full=Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}; Short=MAD homolog {ECO:0000256|RuleBase:RU361195}; Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}; AltName: Full=SMAD family member {ECO:0000256|RuleBase:RU361195};+++[Q6I9T1_HUMAN|Unreviewed]RecName: Full=Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}; Short=MAD homolog {ECO:0000256|RuleBase:RU361195}; Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}; AltName: Full=SMAD family member {ECO:0000256|RuleBase:RU361195};"]
[4122,"'MAN2A2'",2518,2124,2745,2462.33333333333,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis",null,"M00075///N-glycan biosynthesis, complex type","R05984///G00013 + 2 H2O <=> G00014 + 2 alpha-D-Mannose","GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus","GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0030246///carbohydrate binding+++GO:0015923///mannosidase activity+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0004572///mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0004559///alpha-mannosidase activity+++GO:0046872///metal ion binding","GO:0006486///protein glycosylation+++GO:0006013///mannose metabolic process+++GO:0006517///protein deglycosylation+++GO:0005975///carbohydrate metabolic process+++GO:0008152///metabolic process+++GO:0006491///N-glycan processing","mannosidase alpha class 2A member 2","[MA2A2_HUMAN|Reviewed]RecName: Full=Alpha-mannosidase 2x; EC=3.2.1.114 {ECO:0000250|UniProtKB:P28494}; AltName: Full=Alpha-mannosidase IIx; Short=Man IIx; AltName: Full=Mannosidase alpha class 2A member 2; AltName: Full=Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase;+++[A0A0C4DGL1_HUMAN|Unreviewed]RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199}; EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};+++[H0YK77_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000452691}; Flags: Fragment;+++[H0YKH9_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000452813}; Flags: Fragment;+++[H0YKM7_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000452866}; Flags: Fragment;+++[H0YKQ2_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000452897}; Flags: Fragment;+++[H0YKT0_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000452928}; Flags: Fragment;+++[H0YL67_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000453078}; Flags: Fragment;+++[H0YLB9_HUMAN|Unreviewed]RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199}; EC=3.2.1.- {ECO:0000256|RuleBase:RU361199}; Flags: Fragment;+++[H0YLL4_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000453253}; Flags: Fragment;+++[H0YLU3_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000453341}; Flags: Fragment;+++[H0YML7_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000453659}; Flags: Fragment;+++[H0YMU0_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000453740}; Flags: Fragment;+++[H0YNC8_HUMAN|Unreviewed]SubName: Full=Alpha-mannosidase 2x {ECO:0000313|Ensembl:ENSP00000453956}; Flags: Fragment;+++[H0YNG5_HUMAN|Unreviewed]RecName: Full=Alpha-mannosidase {ECO:0000256|RuleBase:RU361199}; EC=3.2.1.- {ECO:0000256|RuleBase:RU361199};"]
[4140,"'MARK3'",856,803,817,825.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0050321///tau-protein kinase activity+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0048156///tau protein binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0035556///intracellular signal transduction+++GO:0032092///positive regulation of protein binding+++GO:0035331///negative regulation of hippo signaling+++GO:0000226///microtubule cytoskeleton organization+++GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade+++GO:0016310///phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0018105///peptidyl-serine phosphorylation+++GO:0036289///peptidyl-serine autophosphorylation","microtubule affinity regulating kinase 3","[MARK3_HUMAN|Reviewed]RecName: Full=MAP/microtubule affinity-regulating kinase 3; EC=2.7.11.1; AltName: Full=C-TAK1; Short=cTAK1; AltName: Full=Cdc25C-associated protein kinase 1; AltName: Full=ELKL motif kinase 2; Short=EMK-2; AltName: Full=Protein kinase STK10; AltName: Full=Ser/Thr protein kinase PAR-1; Short=Par-1a; AltName: Full=Serine/threonine-protein kinase p78;+++[A0A0A0MSZ1_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00804148}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00804148};+++[A2SY06_HUMAN|Unreviewed]SubName: Full=MAP/microtubule affinity-regulating kinase 3 {ECO:0000313|EMBL:ABD15137.1, ECO:0000313|Ensembl:ENSP00000451623}; Flags: Fragment;+++[H0YIY6_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00804148}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00804148}; Flags: Fragment;+++[H0YKJ3_HUMAN|Unreviewed]SubName: Full=MAP/microtubule affinity-regulating kinase 3 {ECO:0000313|Ensembl:ENSP00000452829}; Flags: Fragment;+++[H0YKP9_HUMAN|Unreviewed]SubName: Full=MAP/microtubule affinity-regulating kinase 3 {ECO:0000313|Ensembl:ENSP00000452893}; Flags: Fragment;+++[H0YNV4_HUMAN|Unreviewed]SubName: Full=MAP/microtubule affinity-regulating kinase 3 {ECO:0000313|Ensembl:ENSP00000454169}; Flags: Fragment;+++[J3KNR0_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00804148}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00804148};+++[Q86U11_HUMAN|Unreviewed]SubName: Full=Full-length cDNA clone CS0DE006YM09 of Placenta of Homo sapiens (human) {ECO:0000313|EMBL:CAD62578.1}; Flags: Fragment;"]
[414919,"'C8orf82'",433,519,449,467,{"$nulls":7},"chromosome 8 open reading frame 82","[CH082_HUMAN|Reviewed]RecName: Full=UPF0598 protein C8orf82;+++[H0YEK9_HUMAN|Unreviewed]SubName: Full=UPF0598 protein C8orf82 {ECO:0000313|Ensembl:ENSP00000436060}; Flags: Fragment;+++[H0YF29_HUMAN|Unreviewed]SubName: Full=UPF0598 protein C8orf82 {ECO:0000313|Ensembl:ENSP00000437092}; Flags: Fragment;+++[J3KNI2_HUMAN|Unreviewed]SubName: Full=UPF0598 protein C8orf82 {ECO:0000313|Ensembl:ENSP00000316262};"]
[4166,"'CHST6'",86.81,75.39,80,80.7333333333333,"00533///Glycosaminoglycan biosynthesis - keratan sulfate","H00954///Macular corneal dystrophy (MCD)",null,null,"GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008146///sulfotransferase activity+++GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0016740///transferase activity","GO:0006790///sulfur compound metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0018146///keratan sulfate biosynthetic process","carbohydrate sulfotransferase 6","[CHST6_HUMAN|Reviewed]RecName: Full=Carbohydrate sulfotransferase 6; EC=2.8.2.-; AltName: Full=Corneal N-acetylglucosamine-6-O-sulfotransferase; Short=C-GlcNAc6ST; Short=hCGn6ST; AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta; Short=GST4-beta; AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 5; Short=GlcNAc6ST-5; Short=Gn6st-5;+++[A0A1I9LHJ0_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[A0A1I9LHJ1_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[A0A1I9LHJ2_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[D6QZA0_HUMAN|Unreviewed]SubName: Full=Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 {ECO:0000313|EMBL:ADG26740.1}; Flags: Fragment;+++[D6QZA1_HUMAN|Unreviewed]SubName: Full=Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 {ECO:0000313|EMBL:ADG26741.1}; Flags: Fragment;+++[D6QZA2_HUMAN|Unreviewed]SubName: Full=Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 {ECO:0000313|EMBL:ADG26742.1}; Flags: Fragment;+++[L8E925_HUMAN|Unreviewed]SubName: Full=Alternative protein CHST6 {ECO:0000313|EMBL:CCQ43669.1};"]
[4200,"'ME2'",566.41,527,607,566.803333333333,"02020///Two-component system+++00620///Pyruvate metabolism+++01200///Carbon metabolism",null,null,"R00214///(S)-malate:NAD+ oxidoreductase (decarboxylating)   (S)-Malate + NAD+ <=> Pyruvate + CO2 + NADH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0009055///electron transfer activity+++GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0046872///metal ion binding+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0051287///NAD binding+++GO:0004470///malic enzyme activity","GO:1902031///regulation of NADP metabolic process+++GO:0006108///malate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006090///pyruvate metabolic process","malic enzyme 2","[MAOM_HUMAN|Reviewed]RecName: Full=NAD-dependent malic enzyme, mitochondrial; Short=NAD-ME; EC=1.1.1.38; AltName: Full=Malic enzyme 2; Flags: Precursor;"]
[4215,"'MAP3K3'",405,401,381,395.666666666667,"04010///MAPK signaling pathway+++04722///Neurotrophin signaling pathway+++04912///GnRH signaling pathway+++05166///HTLV-I infection",null,"M00690///MAPK (ERK5) signaling+++M00689///MAPK (p38) signaling+++M00688///MAPK (JNK) signaling",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004709///MAP kinase kinase kinase activity","GO:0001568///blood vessel development+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0000186///activation of MAPKK activity+++GO:0035556///intracellular signal transduction+++GO:0032147///activation of protein kinase activity+++GO:0023014///signal transduction by protein phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:2000773///negative regulation of cellular senescence+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0000165///MAPK cascade+++GO:0071864///positive regulation of cell proliferation in bone marrow+++GO:0006468///protein phosphorylation+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0016310///phosphorylation+++GO:1900745///positive regulation of p38MAPK cascade","mitogen-activated protein kinase kinase kinase 3","[M3K3_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase 3; EC=2.7.11.25; AltName: Full=MAPK/ERK kinase kinase 3; Short=MEK kinase 3; Short=MEKK 3;+++[J3KRN4_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 3 {ECO:0000313|Ensembl:ENSP00000462086};+++[J3KTC4_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 3 {ECO:0000313|Ensembl:ENSP00000462917};+++[J3QRB6_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 3 {ECO:0000313|Ensembl:ENSP00000464130};+++[J3QS19_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 3 {ECO:0000313|Ensembl:ENSP00000464482}; Flags: Fragment;+++[J3QS54_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 3 {ECO:0000313|Ensembl:ENSP00000464532}; Flags: Fragment;+++[Q1PBM3_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 3 variant 2 {ECO:0000313|EMBL:ABE11554.1};+++[Q96HN9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAH08336.1}; Flags: Fragment;"]
[4253,"'MIA2'",483,493,592,522.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070971///endoplasmic reticulum exit site+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0008047///enzyme activator activity+++GO:0003727///single-stranded RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0042954///lipoprotein transporter activity+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0042953///lipoprotein transport+++GO:0035459///cargo loading into vesicle+++GO:0032197///transposition, RNA-mediated+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0006310///DNA recombination+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032527///protein exit from endoplasmic reticulum","MIA SH3 domain ER export factor 2","[CTGE5_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum export factor CTAGE5 {ECO:0000305}; AltName: Full=CTAGE family member 5 ER export factor {ECO:0000312|HGNC:HGNC:7057}; Short=Protein cTAGE-5 {ECO:0000305}; AltName: Full=Meningioma-expressed antigen 6/11 {ECO:0000303|PubMed:9356211};+++[MIA2_HUMAN|Reviewed]RecName: Full=Melanoma inhibitory activity protein 2 {ECO:0000305}; Flags: Precursor;+++[A0A193H6U5_HUMAN|Unreviewed]SubName: Full=TALI {ECO:0000313|EMBL:ANN89694.1};+++[Q05BM1_HUMAN|Unreviewed]SubName: Full=CTAGE5 protein {ECO:0000313|EMBL:AAH39017.1};+++[Q4G155_HUMAN|Unreviewed]SubName: Full=CTAGE5 protein {ECO:0000313|EMBL:AAH29513.1}; Flags: Fragment;+++[Q59FD2_HUMAN|Unreviewed]SubName: Full=CTAGE family, member 5 isoform 1 variant {ECO:0000313|EMBL:BAD92765.1}; Flags: Fragment;"]
[4281,"'MID1'",808,597,679,694.666666666667,"04120///Ubiquitin mediated proteolysis","H00583///Opitz-GBBB syndrome",null,"R02480///Cytochrome c apocytochrome-c-lyase Cytochrome c <=> Apocytochrome c + Heme","GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0005874///microtubule+++GO:0016021///integral component of membrane+++GO:0015630///microtubule cytoskeleton+++GO:0005875///microtubule associated complex+++GO:0005737///cytoplasm+++GO:0005881///cytoplasmic microtubule","GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008017///microtubule binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051219///phosphoprotein binding","GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0000226///microtubule cytoskeleton organization+++GO:0035372///protein localization to microtubule+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007389///pattern specification process","midline 1","[TRI18_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Midline-1; EC=2.3.2.27; AltName: Full=Midin; AltName: Full=Putative transcription factor XPRF; AltName: Full=RING finger protein 59; AltName: Full=RING finger protein Midline-1; AltName: Full=RING-type E3 ubiquitin transferase Midline-1 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 18;+++[A0A024RBV4_HUMAN|Unreviewed]SubName: Full=Midline 1 (Opitz/BBB syndrome), isoform CRA_a {ECO:0000313|EMBL:EAW98781.1};+++[A0A087X0X0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000483707};+++[A0A087X255_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000484712};+++[C9J453_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000391154}; Flags: Fragment;+++[C9JZJ7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Midline-1 {ECO:0000313|Ensembl:ENSP00000387771}; Flags: Fragment;"]
[4288,"'MKI67'",2,0,1,1,{"$nulls":4},"GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0016604///nuclear body+++GO:0016020///membrane+++GO:0000793///condensed chromosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding+++GO:0003723///RNA binding","GO:0007088///regulation of mitotic nuclear division+++GO:0008283///cell proliferation+++GO:0007049///cell cycle+++GO:1902275///regulation of chromatin organization+++GO:0051983///regulation of chromosome segregation","marker of proliferation Ki-67","[KI67_HUMAN|Reviewed]RecName: Full=Proliferation marker protein Ki-67 {ECO:0000305}; AltName: Full=Antigen identified by monoclonal antibody Ki-67 {ECO:0000303|PubMed:8227122}; Short=Antigen KI-67 {ECO:0000305}; Short=Antigen Ki67 {ECO:0000305};+++[Q70L72_HUMAN|Unreviewed]SubName: Full=KI67 Antigen {ECO:0000313|EMBL:CAD99007.1}; Flags: Fragment;+++[Q70L73_HUMAN|Unreviewed]SubName: Full=KI67 Antigen {ECO:0000313|EMBL:CAD99006.1}; Flags: Fragment;+++[Q70L74_HUMAN|Unreviewed]SubName: Full=KI67 Antigen {ECO:0000313|EMBL:CAD99005.1}; Flags: Fragment;"]
[4323,"'MMP14'",26226,27028,22391,25215,"04668///TNF signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++04912///GnRH signaling pathway","H02089///Winchester syndrome",null,null,"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0045111///intermediate filament cytoskeleton+++GO:0005737///cytoplasm+++GO:0042470///melanosome+++GO:0005886///plasma membrane+++GO:0005796///Golgi lumen+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005925///focal adhesion+++GO:0031410///cytoplasmic vesicle+++GO:0031012///extracellular matrix+++GO:0044354///macropinosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0008270///zinc ion binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0070006///metalloaminopeptidase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0008237///metallopeptidase activity+++GO:0005178///integrin binding+++GO:0004252///serine-type endopeptidase activity+++GO:0046872///metal ion binding+++GO:0004175///endopeptidase activity","GO:0030307///positive regulation of cell growth+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0043627///response to estrogen+++GO:0030335///positive regulation of cell migration+++GO:0060322///head development+++GO:0001541///ovarian follicle development+++GO:0014070///response to organic cyclic compound+++GO:1905523///positive regulation of macrophage migration+++GO:0006508///proteolysis+++GO:0001666///response to hypoxia+++GO:0001935///endothelial cell proliferation+++GO:0030324///lung development+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0001503///ossification+++GO:0009725///response to hormone+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0043615///astrocyte cell migration+++GO:0009612///response to mechanical stimulus+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0010954///positive regulation of protein processing+++GO:0030574///collagen catabolic process+++GO:1990834///response to odorant+++GO:0048870///cell motility+++GO:0060348///bone development+++GO:0031638///zymogen activation+++GO:0001958///endochondral ossification+++GO:0001525///angiogenesis+++GO:0016485///protein processing+++GO:0097094///craniofacial suture morphogenesis+++GO:0006979///response to oxidative stress+++GO:0022617///extracellular matrix disassembly+++GO:0035987///endodermal cell differentiation+++GO:0035988///chondrocyte proliferation+++GO:0045579///positive regulation of B cell differentiation+++GO:0008584///male gonad development+++GO:0048771///tissue remodeling+++GO:0016477///cell migration+++GO:0010831///positive regulation of myotube differentiation+++GO:0048701///embryonic cranial skeleton morphogenesis","matrix metallopeptidase 14","[MMP14_HUMAN|Reviewed]RecName: Full=Matrix metalloproteinase-14; Short=MMP-14; EC=3.4.24.80; AltName: Full=MMP-X1; AltName: Full=Membrane-type matrix metalloproteinase 1; Short=MT-MMP 1; Short=MTMMP1; AltName: Full=Membrane-type-1 matrix metalloproteinase; Short=MT1-MMP; Short=MT1MMP; Flags: Precursor;+++[F8VP90_HUMAN|Unreviewed]RecName: Full=Matrix metalloproteinase {ECO:0000256|RuleBase:RU364080}; EC=3.4.24.- {ECO:0000256|RuleBase:RU364080};+++[F8W1B7_HUMAN|Unreviewed]RecName: Full=Matrix metalloproteinase {ECO:0000256|RuleBase:RU364080}; EC=3.4.24.- {ECO:0000256|RuleBase:RU364080}; Flags: Fragment;+++[K4RH61_HUMAN|Unreviewed]SubName: Full=Matrix metalloproteinase 14 (Membrane-inserted) {ECO:0000313|EMBL:CCK73138.1};"]
[4330,"'MN1'",938,781,867,862,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process+++GO:0001957///intramembranous ossification","MN1 proto-oncogene, transcriptional regulator","[MN1_HUMAN|Reviewed]RecName: Full=Transcriptional activator MN1 {ECO:0000305}; AltName: Full=Probable tumor suppressor protein MN1 {ECO:0000305};+++[A0A024R1C3_HUMAN|Unreviewed]SubName: Full=Meningioma (Disrupted in balanced translocation) 1, isoform CRA_a {ECO:0000313|EMBL:EAW59742.1};+++[A5HML1_HUMAN|Unreviewed]SubName: Full=Meningioma (Disrupted in balanced translocation) 1 {ECO:0000313|EMBL:ABQ01232.1};+++[H7C105_HUMAN|Unreviewed]SubName: Full=Transcriptional activator MN1 {ECO:0000313|Ensembl:ENSP00000397805}; Flags: Fragment;"]
[43847,"'KLK14'",2,1,0,1,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0030141///secretory granule","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0008236///serine-type peptidase activity+++GO:0004252///serine-type endopeptidase activity","GO:0048730///epidermis morphogenesis+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0009566///fertilization+++GO:0006508///proteolysis+++GO:0070684///seminal clot liquefaction+++GO:0070268///cornification+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway","kallikrein related peptidase 14","[KLK14_HUMAN|Reviewed]RecName: Full=Kallikrein-14; Short=hK14; EC=3.4.21.-; AltName: Full=Kallikrein-like protein 6; Short=KLK-L6; Flags: Precursor;+++[A0A024R4M6_HUMAN|Unreviewed]SubName: Full=Kallikrein 14, isoform CRA_a {ECO:0000313|EMBL:EAW71983.1};"]
[440275,"'EIF2AK4'",1081,776,737,864.666666666667,"04141///Protein processing in endoplasmic reticulum+++05160///Hepatitis C+++05162///Measles+++04140///Autophagy - animal+++05164///Influenza A+++04138///Autophagy - yeast+++05168///Herpes simplex infection+++05169///Epstein-Barr virus infection","H01866///Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis+++H01621///Pulmonary arterial hypertension (PAH)",null,null,"GO:0005844///polysome+++GO:0005737///cytoplasm+++GO:0022626///cytosolic ribosome","GO:0004694///eukaryotic translation initiation factor 2alpha kinase activity+++GO:0000049///tRNA binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0061630///ubiquitin protein ligase activity","GO:0045947///negative regulation of translational initiation+++GO:0010998///regulation of translational initiation by eIF2 alpha phosphorylation+++GO:0016032///viral process+++GO:0032792///negative regulation of CREB transcription factor activity+++GO:0007050///cell cycle arrest+++GO:0032057///negative regulation of translational initiation in response to stress+++GO:0046777///protein autophosphorylation+++GO:0002230///positive regulation of defense response to virus by host+++GO:0034198///cellular response to amino acid starvation+++GO:0002250///adaptive immune response+++GO:0034644///cellular response to UV+++GO:0007399///nervous system development+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:0000077///DNA damage checkpoint+++GO:0045665///negative regulation of neuron differentiation+++GO:0007616///long-term memory+++GO:0070417///cellular response to cold+++GO:0006417///regulation of translation+++GO:0071264///positive regulation of translational initiation in response to starvation+++GO:0006468///protein phosphorylation+++GO:0007049///cell cycle+++GO:0002376///immune system process+++GO:0060733///regulation of eIF2 alpha phosphorylation by amino acid starvation+++GO:0006446///regulation of translational initiation+++GO:0019081///viral translation+++GO:0036492///eiF2alpha phosphorylation in response to endoplasmic reticulum stress+++GO:1990138///neuron projection extension+++GO:0002286///T cell activation involved in immune response+++GO:0051607///defense response to virus+++GO:0039520///induction by virus of host autophagy+++GO:0060259///regulation of feeding behavior+++GO:1990253///cellular response to leucine starvation+++GO:0007612///learning+++GO:0002821///positive regulation of adaptive immune response+++GO:0016310///phosphorylation+++GO:0044828///negative regulation by host of viral genome replication+++GO:0016567///protein ubiquitination","eukaryotic translation initiation factor 2 alpha kinase 4","[E2AK4_HUMAN|Reviewed]RecName: Full=eIF-2-alpha kinase GCN2 {ECO:0000250|UniProtKB:Q9QZ05}; EC=2.7.11.1 {ECO:0000250|UniProtKB:Q9QZ05}; AltName: Full=Eukaryotic translation initiation factor 2-alpha kinase 4 {ECO:0000312|HGNC:HGNC:19687}; AltName: Full=GCN2-like protein;+++[H0YME5_HUMAN|Unreviewed]SubName: Full=eIF-2-alpha kinase GCN2 {ECO:0000313|Ensembl:ENSP00000453575}; Flags: Fragment;+++[H0YND8_HUMAN|Unreviewed]SubName: Full=eIF-2-alpha kinase GCN2 {ECO:0000313|Ensembl:ENSP00000453968};+++[H0YNY9_HUMAN|Unreviewed]SubName: Full=eIF-2-alpha kinase GCN2 {ECO:0000313|Ensembl:ENSP00000454210}; Flags: Fragment;"]
[440498,"'HSBP1L1'",75,91,93,86.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003714///transcription corepressor activity","GO:0070370///cellular heat acclimation+++GO:1903507///negative regulation of nucleic acid-templated transcription","heat shock factor binding protein 1 like 1","[HSBPL_HUMAN|Reviewed]RecName: Full=Heat shock factor-binding protein 1-like protein 1;+++[K7ENV5_HUMAN|Unreviewed]SubName: Full=Heat shock factor-binding protein 1-like protein 1 {ECO:0000313|Ensembl:ENSP00000467108};"]
[441027,"'TMEM150C'",30,16,37,27.6666666666667,{"$nulls":4},"GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0005764///lysosome+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0008381///mechanosensitive ion channel activity","GO:0019230///proprioception+++GO:0055085///transmembrane transport+++GO:0010506///regulation of autophagy+++GO:0071260///cellular response to mechanical stimulus","transmembrane protein 150C","[T150C_HUMAN|Reviewed]RecName: Full=Transmembrane protein 150C;+++[D6RAQ9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 150C {ECO:0000313|Ensembl:ENSP00000421812};+++[D6RDW6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 150C {ECO:0000313|Ensembl:ENSP00000414988}; Flags: Fragment;"]
[441239,"'LOC441239'",5,13,18,12,{"$nulls":7},"uncharacterized LOC441239","[Q6P462_HUMAN|Unreviewed]SubName: Full=LOC441239 protein {ECO:0000313|EMBL:AAH63653.1};"]
[442319,"'ZNF727'",2,3,1,2,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 727","[ZN727_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 727; AltName: Full=Zinc finger protein 727 pseudogene;"]
[445,"'ASS1'",1118,1183,1075,1125.33333333333,"05418///Fluid shear stress and atherosclerosis+++01130///Biosynthesis of antibiotics+++00250///Alanine, aspartate and glutamate metabolism+++01110///Biosynthesis of secondary metabolites+++00220///Arginine biosynthesis+++01100///Metabolic pathways+++01230///Biosynthesis of amino acids","H00185///Citrullinemia (CTLN)+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)","M00029///Urea cycle+++M00844///Arginine biosynthesis, ornithine => arginine+++M00845///Arginine biosynthesis, glutamate => acetylcitrulline => arginine","R01954///L-Citrulline:L-aspartate ligase (AMP-forming)   ATP + L-Citrulline + L-Aspartate <=> AMP + Diphosphate + N-(L-Arginino)succinate","GO:0043005///neuron projection+++GO:0005783///endoplasmic reticulum+++GO:0005764///lysosome+++GO:0043204///perikaryon+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0070852///cell body fiber+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0043209///myelin sheath","GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004055///argininosuccinate synthase activity+++GO:0000166///nucleotide binding+++GO:0016874///ligase activity+++GO:0016597///amino acid binding+++GO:0015643///toxic substance binding","GO:1903038///negative regulation of leukocyte cell-cell adhesion+++GO:0007494///midgut development+++GO:0009636///response to toxic substance+++GO:0071356///cellular response to tumor necrosis factor+++GO:0070542///response to fatty acid+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0043434///response to peptide hormone+++GO:0001822///kidney development+++GO:0010043///response to zinc ion+++GO:0007623///circadian rhythm+++GO:0001889///liver development+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0071400///cellular response to oleic acid+++GO:0010046///response to mycotoxin+++GO:0042493///response to drug+++GO:0071377///cellular response to glucagon stimulus+++GO:0032496///response to lipopolysaccharide+++GO:0006953///acute-phase response+++GO:0071242///cellular response to ammonium ion+++GO:0060539///diaphragm development+++GO:0007584///response to nutrient+++GO:0048545///response to steroid hormone+++GO:0043200///response to amino acid+++GO:0006531///aspartate metabolic process+++GO:0014075///response to amine+++GO:0000052///citrulline metabolic process+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0007568///aging+++GO:0006526///arginine biosynthetic process+++GO:0071346///cellular response to interferon-gamma+++GO:0071418///cellular response to amine stimulus+++GO:0051384///response to glucocorticoid+++GO:0008652///cellular amino acid biosynthetic process+++GO:0071230///cellular response to amino acid stimulus+++GO:0071222///cellular response to lipopolysaccharide+++GO:0060416///response to growth hormone+++GO:0071320///cellular response to cAMP+++GO:0000053///argininosuccinate metabolic process+++GO:0000050///urea cycle+++GO:0032355///response to estradiol","argininosuccinate synthase 1","[ASSY_HUMAN|Reviewed]RecName: Full=Argininosuccinate synthase {ECO:0000305}; EC=6.3.4.5 {ECO:0000269|PubMed:18473344, ECO:0000269|PubMed:27287393, ECO:0000269|PubMed:8792870}; AltName: Full=Citrulline--aspartate ligase;+++[A0A0S2Z3B6_HUMAN|Unreviewed]SubName: Full=Argininosuccinate synthase 1 isoform 2 {ECO:0000313|EMBL:ALQ33382.1}; Flags: Fragment;+++[A0A0S2Z3D8_HUMAN|Unreviewed]SubName: Full=Argininosuccinate synthase 1 isoform 3 {ECO:0000313|EMBL:ALQ33383.1};+++[A0A0S2Z3F1_HUMAN|Unreviewed]SubName: Full=Argininosuccinate synthase 1 isoform 4 {ECO:0000313|EMBL:ALQ33384.1}; Flags: Fragment;+++[Q5T6L4_HUMAN|Unreviewed]SubName: Full=Argininosuccinate synthase 1 isoform 1 {ECO:0000313|EMBL:ALQ33381.1}; SubName: Full=Argininosuccinate synthetase, isoform CRA_a {ECO:0000313|EMBL:EAW87932.1}; SubName: Full=cDNA, FLJ96050, highly similar to Homo sapiens argininosuccinate synthetase (ASS), transcript variant1, mRNA {ECO:0000313|EMBL:BAG37558.1};+++[Q5T6L5_HUMAN|Unreviewed]SubName: Full=Argininosuccinate synthase {ECO:0000313|Ensembl:ENSP00000397785}; Flags: Fragment;+++[Q5T6L6_HUMAN|Unreviewed]SubName: Full=Argininosuccinate synthase {ECO:0000313|Ensembl:ENSP00000394212}; Flags: Fragment;+++[Q8NFZ7_HUMAN|Unreviewed]SubName: Full=Argininosuccinate synthetase {ECO:0000313|EMBL:AAM60751.1}; Flags: Fragment;"]
[4515,"'MTCP1'",8.48,8.58,0,5.68666666666667,"04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0000151///ubiquitin ligase complex+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0070531///BRCA1-A complex+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex+++GO:0000152///nuclear ubiquitin ligase complex+++GO:0070552///BRISC complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0008237///metallopeptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0046872///metal ion binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0030234///enzyme regulator activity+++GO:0019901///protein kinase binding+++GO:0031593///polyubiquitin modification-dependent protein binding","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0070536///protein K63-linked deubiquitination+++GO:0010212///response to ionizing radiation+++GO:0007049///cell cycle+++GO:0006302///double-strand break repair+++GO:0051301///cell division+++GO:0045739///positive regulation of DNA repair+++GO:0008283///cell proliferation+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0010165///response to X-ray+++GO:0000422///autophagy of mitochondrion+++GO:0016579///protein deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination","mature T cell proliferation 1","[MTCP1_HUMAN|Reviewed]RecName: Full=Protein p13 MTCP-1; Short=p13MTCP1; AltName: Full=Mature T-cell proliferation-1 type B1; Short=MTCP-1 type B1;"]
[4582,"'MUC1'",863,1092,922,959,null,"H00541///Autosomal dominant tubulointerstitial kidney disease (ADTKD)+++H02012///Medullary cystic kidney disease (MCKD)",null,null,"GO:0005739///mitochondrion+++GO:0070062///extracellular exosome+++GO:0031966///mitochondrial membrane+++GO:0000790///nuclear chromatin+++GO:0005887///integral component of plasma membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0031526///brush border membrane+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031982///vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0042383///sarcolemma","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0080101///phosphatidyl-N-dimethylethanolamine N-methyltransferase activity+++GO:0004608///phosphatidylethanolamine N-methyltransferase activity+++GO:0008757///S-adenosylmethionine-dependent methyltransferase activity+++GO:0005515///protein binding+++GO:0000773///phosphatidyl-N-methylethanolamine N-methyltransferase activity+++GO:0003712///transcription coregulator activity+++GO:0008429///phosphatidylethanolamine binding+++GO:0002039///p53 binding+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006629///lipid metabolic process+++GO:0043618///regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0006650///glycerophospholipid metabolic process+++GO:0001835///blastocyst hatching+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0007584///response to nutrient+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0050747///positive regulation of lipoprotein metabolic process+++GO:0045471///response to ethanol+++GO:0006686///sphingomyelin biosynthetic process+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0033273///response to vitamin+++GO:0008283///cell proliferation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0008285///negative regulation of cell proliferation+++GO:0046500///S-adenosylmethionine metabolic process+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0042493///response to drug+++GO:0046498///S-adenosylhomocysteine metabolic process+++GO:0016266///O-glycan processing+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0043200///response to amino acid+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0032259///methylation+++GO:0090240///positive regulation of histone H4 acetylation","mucin 1, cell surface associated","[MUC1_HUMAN|Reviewed]RecName: Full=Mucin-1; Short=MUC-1; AltName: Full=Breast carcinoma-associated antigen DF3; AltName: Full=Cancer antigen 15-3; Short=CA 15-3; AltName: Full=Carcinoma-associated mucin; AltName: Full=Episialin; AltName: Full=H23AG; AltName: Full=Krebs von den Lungen-6; Short=KL-6; AltName: Full=PEMT; AltName: Full=Peanut-reactive urinary mucin; Short=PUM; AltName: Full=Polymorphic epithelial mucin; Short=PEM; AltName: Full=Tumor-associated epithelial membrane antigen; Short=EMA; AltName: Full=Tumor-associated mucin; AltName: CD_antigen=CD227; Contains: RecName: Full=Mucin-1 subunit alpha; Short=MUC1-NT; Short=MUC1-alpha; Contains: RecName: Full=Mucin-1 subunit beta; Short=MUC1-beta; AltName: Full=MUC1-CT; Flags: Precursor;+++[A0A087WTR1_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000478068}; Flags: Fragment;+++[A0A087WVJ0_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000479471}; Flags: Fragment;+++[A0A087WWM1_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000480333};+++[A0A087WWM2_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000480335};+++[A0A087WZI8_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000482688};+++[A0A087WZZ6_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000482988};+++[A0A087X061_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000483128};+++[A0A087X0L2_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000483482};+++[A0A087X2A4_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000484824};+++[A0A0A0MRB3_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000343482};+++[A0A0A0MSH4_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000388172};+++[A0A0C4DGW3_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000481231};+++[A5YRU0_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T1 {ECO:0000313|EMBL:ABQ59617.1};+++[A5YRU1_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T2 {ECO:0000313|EMBL:ABQ59618.1};+++[A5YRU2_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T3 {ECO:0000313|EMBL:ABQ59619.1};+++[A5YRU3_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T4 {ECO:0000313|EMBL:ABQ59620.1};+++[A5YRU4_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T5 {ECO:0000313|EMBL:ABQ59621.1};+++[A5YRU5_HUMAN|Unreviewed]SubName: Full=MUC1 isoform Z-LSP {ECO:0000313|EMBL:ABQ59622.1};+++[A5YRU6_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T6 {ECO:0000313|EMBL:ABQ59623.1};+++[A5YRU7_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T7 {ECO:0000313|EMBL:ABQ59624.1};+++[A5YRU8_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T8 {ECO:0000313|EMBL:ABQ59625.1};+++[A5YRU9_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T9 {ECO:0000313|EMBL:ABQ59626.1};+++[A5YRV0_HUMAN|Unreviewed]SubName: Full=MUC1 isoform G-LSP {ECO:0000313|EMBL:ABQ59627.1};+++[A5YRV2_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T11 {ECO:0000313|EMBL:ABQ59629.1};+++[A5YRV3_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T12 {ECO:0000313|EMBL:ABQ59630.1};+++[A5YRV4_HUMAN|Unreviewed]SubName: Full=MUC1 isoform T13 {ECO:0000313|EMBL:ABQ59631.1};+++[A6ZID4_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M1 {ECO:0000313|EMBL:ABS01293.1};+++[A6ZID5_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M2 {ECO:0000313|EMBL:ABS01294.1};+++[A6ZID6_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M3 {ECO:0000313|EMBL:ABS01295.1};+++[A6ZID7_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M4 {ECO:0000313|EMBL:ABS01296.1};+++[A6ZID8_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M5 {ECO:0000313|EMBL:ABS01297.1};+++[A6ZIE1_HUMAN|Unreviewed]SubName: Full=MUC1 isoform SV4-LSP {ECO:0000313|EMBL:ABS01300.1};+++[A6ZIE2_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M8 {ECO:0000313|EMBL:ABS01301.1};+++[A6ZIE3_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M9 {ECO:0000313|EMBL:ABS01302.1}; SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000483581};+++[A6ZIE4_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M10 {ECO:0000313|EMBL:ABS01303.1}; SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000483473};+++[A6ZIE5_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M11 {ECO:0000313|EMBL:ABS01304.1};+++[A6ZIE6_HUMAN|Unreviewed]SubName: Full=MUC1 isoform S-LSP {ECO:0000313|EMBL:ABS01305.1};+++[A6ZIE7_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M12 {ECO:0000313|EMBL:ABS01306.1};+++[A6ZIE8_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M13 {ECO:0000313|EMBL:ABS01307.1};+++[A6ZIE9_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M14 {ECO:0000313|EMBL:ABS01308.1};+++[A6ZIF0_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M15 {ECO:0000313|EMBL:ABS01309.1};+++[A6ZIF1_HUMAN|Unreviewed]SubName: Full=MUC1 isoform M16 {ECO:0000313|EMBL:ABS01310.1};+++[B1AVQ7_HUMAN|Unreviewed]SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000389098};+++[B6EC89_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J18 {ECO:0000313|EMBL:ACI25178.1}; SubName: Full=MUC1 isoform J2 {ECO:0000313|EMBL:ACI25161.1}; SubName: Full=MUC1 isoform J4 {ECO:0000313|EMBL:ACI25163.1}; SubName: Full=MUC1 isoform J5 {ECO:0000313|EMBL:ACI25164.1}; SubName: Full=MUC1 isoform J6 {ECO:0000313|EMBL:ACI25165.1}; SubName: Full=MUC1 isoform J7 {ECO:0000313|EMBL:ACI25166.1}; SubName: Full=MUC1 isoform J9 {ECO:0000313|EMBL:ACI25168.1};+++[B6EC96_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J8 {ECO:0000313|EMBL:ACI25167.1};+++[B6ECA2_HUMAN|Unreviewed]SubName: Full=MUC1 isoform SV7-LSP {ECO:0000313|EMBL:ACI25173.1};+++[B6ECA3_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J14 {ECO:0000313|EMBL:ACI25174.1};+++[B6ECA4_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J15 {ECO:0000313|EMBL:ACI25175.1};+++[B6ECA9_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J20 {ECO:0000313|EMBL:ACI25180.1};+++[B6ECB0_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J21 {ECO:0000313|EMBL:ACI25181.1};+++[B6ECB1_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J22 {ECO:0000313|EMBL:ACI25182.1};+++[B6ECB2_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J23 {ECO:0000313|EMBL:ACI25183.1};+++[B6ECB3_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J24 {ECO:0000313|EMBL:ACI25184.1};+++[B6ECB5_HUMAN|Unreviewed]SubName: Full=MUC1 isoform J26 {ECO:0000313|EMBL:ACI25186.1}; SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000484006};+++[Q14877_HUMAN|Unreviewed]SubName: Full=Mucin {ECO:0000313|EMBL:AAA57348.1}; Flags: Fragment;+++[Q7Z536_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV10 {ECO:0000313|EMBL:AAP97029.1}; SubName: Full=Mucin-1 {ECO:0000313|Ensembl:ENSP00000484730};+++[Q7Z537_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV9 {ECO:0000313|EMBL:AAP97028.1};+++[Q7Z538_HUMAN|Unreviewed]SubName: Full=Mucin short variant PC2 {ECO:0000313|EMBL:AAP97027.1};+++[Q7Z539_HUMAN|Unreviewed]SubName: Full=Mucin short variant PC1 {ECO:0000313|EMBL:AAP97026.1};+++[Q7Z540_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV7 {ECO:0000313|EMBL:AAP97025.1};+++[Q7Z541_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV8 {ECO:0000313|EMBL:AAP97024.1};+++[Q7Z542_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV4 {ECO:0000313|EMBL:AAP97023.1};+++[Q7Z543_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV3 {ECO:0000313|EMBL:AAP97022.1};+++[Q7Z544_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV2 {ECO:0000313|EMBL:AAP97021.1};+++[Q7Z545_HUMAN|Unreviewed]SubName: Full=Mucin short variant SV1 {ECO:0000313|EMBL:AAP97020.1};+++[Q7Z546_HUMAN|Unreviewed]SubName: Full=Mucin short variant G {ECO:0000313|EMBL:AAP97019.1};+++[Q7Z549_HUMAN|Unreviewed]SubName: Full=Mucin short variant E1 {ECO:0000313|EMBL:AAP97016.1};+++[Q7Z551_HUMAN|Unreviewed]SubName: Full=Mucin short variant S1 {ECO:0000313|EMBL:AAP97014.1};"]
[4608,"'MYBPH'",43,40,68,50.3333333333333,null,"H01649///Schizophrenia",null,null,"GO:0032982///myosin filament","GO:0005515///protein binding+++GO:0008307///structural constituent of muscle","GO:0006942///regulation of striated muscle contraction+++GO:0007155///cell adhesion","myosin binding protein H","[MYBPH_HUMAN|Reviewed]RecName: Full=Myosin-binding protein H; Short=MyBP-H; AltName: Full=H-protein;+++[A0A087X023_HUMAN|Unreviewed]SubName: Full=Myosin-binding protein H {ECO:0000313|Ensembl:ENSP00000483045};"]
[4629,"'MYH11'",150,290,152,197.333333333333,"04530///Tight junction","H00604///Deafness, autosomal dominant+++H02052///Sebastian syndrome+++H01740///Macrothrombocytopenia+++H01630///Patent ductus arteriosus+++H00233///MYH9-related disease+++H00872///Trismus-pseudocamptodactyly syndrome+++H01229///Inclusion body myopathy 3 (IBM3)+++H00801///Familial thoracic aortic aneurysm and dissection (TAAD)+++H00811///Distal arthrogryposis (DA)+++H02051///May-Hegglin anomaly+++H02053///Fechtner syndrome+++H00578///Epstein syndrome",null,null,"GO:0005859///muscle myosin complex+++GO:0042470///melanosome+++GO:0016459///myosin complex+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0032982///myosin filament","GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0005524///ATP binding+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0051015///actin filament binding+++GO:0003779///actin binding+++GO:0005516///calmodulin binding","GO:0006939///smooth muscle contraction+++GO:0006936///muscle contraction+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0048251///elastic fiber assembly+++GO:0048739///cardiac muscle fiber development","myosin heavy chain 11","[MYH11_HUMAN|Reviewed]RecName: Full=Myosin-11; AltName: Full=Myosin heavy chain 11; AltName: Full=Myosin heavy chain, smooth muscle isoform; AltName: Full=SMMHC;+++[A0A024QZJ4_HUMAN|Unreviewed]SubName: Full=Myosin, heavy polypeptide 11, smooth muscle, isoform CRA_a {ECO:0000313|EMBL:EAW53925.1};+++[A0A024QZJ6_HUMAN|Unreviewed]SubName: Full=Myosin, heavy polypeptide 11, smooth muscle, isoform CRA_b {ECO:0000313|EMBL:EAW53930.1};+++[B1PS43_HUMAN|Unreviewed]SubName: Full=Myosin heavy chain 11 smooth muscle isoform {ECO:0000313|EMBL:ACB05996.1};+++[Q4G140_HUMAN|Unreviewed]SubName: Full=MYH11 protein {ECO:0000313|EMBL:AAH31040.1};+++[Q66K75_HUMAN|Unreviewed]SubName: Full=MYH11 protein {ECO:0000313|EMBL:AAH80545.1}; Flags: Fragment;"]
[4633,"'MYL2'",4,4,4,4,"04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04371///Apelin signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04810///Regulation of actin cytoskeleton+++04260///Cardiac muscle contraction+++05410///Hypertrophic cardiomyopathy (HCM)+++04261///Adrenergic signaling in cardiomyocytes+++04530///Tight junction","H00292///Hypertrophic cardiomyopathy (HCM)",null,null,"GO:0005737///cytoplasm+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0097512///cardiac myofibril+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016459///myosin complex+++GO:0031672///A band","GO:0032036///myosin heavy chain binding+++GO:0003785///actin monomer binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle","GO:0002026///regulation of the force of heart contraction+++GO:0030049///muscle filament sliding+++GO:0030308///negative regulation of cell growth+++GO:0048747///muscle fiber development+++GO:0009791///post-embryonic development+++GO:0042694///muscle cell fate specification+++GO:0003007///heart morphogenesis+++GO:0055003///cardiac myofibril assembly+++GO:0060047///heart contraction+++GO:0007507///heart development+++GO:0060048///cardiac muscle contraction+++GO:0098735///positive regulation of the force of heart contraction+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0006942///regulation of striated muscle contraction","myosin light chain 2","[MLRV_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 2, ventricular/cardiac muscle isoform {ECO:0000305}; Short=MLC-2 {ECO:0000250|UniProtKB:P08733}; Short=MLC-2v; AltName: Full=Cardiac myosin light chain 2 {ECO:0000303|Ref.3}; AltName: Full=Myosin light chain 2, slow skeletal/ventricular muscle isoform {ECO:0000250|UniProtKB:Q7M2V4}; Short=MLC-2s/v {ECO:0000250|UniProtKB:Q7M2V4}; AltName: Full=Ventricular myosin light chain 2 {ECO:0000303|PubMed:2704627};+++[A0A191TDH3_HUMAN|Unreviewed]SubName: Full=Myosin light chain-2 {ECO:0000313|EMBL:ANI86418.1}; Flags: Fragment;+++[G3V1V8_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 2, ventricular/cardiac muscle isoform {ECO:0000313|Ensembl:ENSP00000447154}; SubName: Full=Myosin, light polypeptide 2, regulatory, cardiac, slow, isoform CRA_b {ECO:0000313|EMBL:EAW97944.1};+++[Q6IB42_HUMAN|Unreviewed]SubName: Full=MYL2 protein {ECO:0000313|EMBL:CAG33243.1}; SubName: Full=Myosin, light polypeptide 2, regulatory, cardiac, slow, isoform CRA_a {ECO:0000313|EMBL:EAW97943.1}; SubName: Full=cDNA, FLJ92288, highly similar to Homo sapiens myosin, light polypeptide 2, regulatory, cardiac, slow (MYL2), mRNA {ECO:0000313|EMBL:BAG34951.1};"]
[4670,"'HNRNPM'",1210,1187,1104,1167,"03040///Spliceosome",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0016363///nuclear matrix+++GO:0005681///spliceosomal complex+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0071014///post-mRNA release spliceosomal complex+++GO:0016020///membrane+++GO:0071013///catalytic step 2 spliceosome+++GO:0042382///paraspeckles+++GO:1990904///ribonucleoprotein complex","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:2000815///regulation of mRNA stability involved in response to oxidative stress+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process","heterogeneous nuclear ribonucleoprotein M","[HNRPM_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein M; Short=hnRNP M;+++[A0A087X0X3_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000483715};+++[M0QY96_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000469681}; Flags: Fragment;+++[M0QYL3_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000469906}; Flags: Fragment;+++[M0QYQ7_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000470017}; Flags: Fragment;+++[M0QZM1_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000470635}; Flags: Fragment;+++[M0R019_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000470932}; Flags: Fragment;+++[M0R0N3_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000471339}; Flags: Fragment;+++[M0R0Y6_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000471530};+++[M0R2I7_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000472599}; Flags: Fragment;+++[M0R2T0_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M {ECO:0000313|Ensembl:ENSP00000472789}; Flags: Fragment;+++[Q59ES8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein M isoform a variant {ECO:0000313|EMBL:BAD92970.1}; Flags: Fragment;+++[Q6P2D7_HUMAN|Unreviewed]SubName: Full=HNRPM protein {ECO:0000313|EMBL:AAH64588.1}; Flags: Fragment;"]
[4671,"'NAIP'",133.2,101,155.54,129.913333333333,"05134///Legionellosis+++04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0016323///basolateral plasma membrane+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0030414///peptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity","GO:0006954///inflammatory response+++GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0010466///negative regulation of peptidase activity+++GO:0007399///nervous system development+++GO:0002376///immune system process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0043524///negative regulation of neuron apoptotic process","NLR family apoptosis inhibitory protein","[BIRC1_HUMAN|Reviewed]RecName: Full=Baculoviral IAP repeat-containing protein 1; AltName: Full=Neuronal apoptosis inhibitory protein;+++[A0A0G2JNC7_HUMAN|Unreviewed]SubName: Full=Baculoviral IAP repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000481094};+++[A0A0G2JQE0_HUMAN|Unreviewed]SubName: Full=Baculoviral IAP repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000485780}; Flags: Fragment;+++[A0A0G2JS53_HUMAN|Unreviewed]SubName: Full=Baculoviral IAP repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000487347};+++[B7ZLE8_HUMAN|Unreviewed]SubName: Full=Baculoviral IAP repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000479075}; SubName: Full=NAIP protein {ECO:0000313|EMBL:AAI43762.1};+++[E5RJA3_HUMAN|Unreviewed]SubName: Full=Baculoviral IAP repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429154};+++[E7EQW0_HUMAN|Unreviewed]SubName: Full=Baculoviral IAP repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429545};+++[H0YAX2_HUMAN|Unreviewed]SubName: Full=Baculoviral IAP repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000428226}; Flags: Fragment;"]
[4691,"'NCL'",5532,4736,4670,4979.33333333333,"05130///Pathogenic Escherichia coli infection",{"$nulls":3},"GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005938///cell cortex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042802///identical protein binding+++GO:0003723///RNA binding+++GO:0008022///protein C-terminus binding+++GO:0044547///DNA topoisomerase binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0042162///telomeric DNA binding","GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0017148///negative regulation of translation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I","nucleolin","[NUCL_HUMAN|Reviewed]RecName: Full=Nucleolin; AltName: Full=Protein C23;+++[A0A024R4A0_HUMAN|Unreviewed]SubName: Full=Nucleolin, isoform CRA_b {ECO:0000313|EMBL:EAW70963.1};+++[B3KM80_HUMAN|Unreviewed]SubName: Full=Nucleolin, isoform CRA_c {ECO:0000313|EMBL:EAW70962.1}; SubName: Full=cDNA FLJ10452 fis, clone NT2RP1000966, highly similar to NUCLEOLIN {ECO:0000313|EMBL:BAG50892.1};"]
[4707,"'NDUFB1'",236,219,207,220.666666666667,"00190///Oxidative phosphorylation+++05016///Huntington's disease+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01100///Metabolic pathways+++04714///Thermogenesis+++05010///Alzheimer's disease+++04723///Retrograde endocannabinoid signaling",null,"M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0005743///mitochondrial inner membrane+++GO:0070469///respiratory chain+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005747///mitochondrial respiratory chain complex I","GO:0003954///NADH dehydrogenase activity+++GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0055114///oxidation-reduction process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone","NADH:ubiquinone oxidoreductase subunit B1","[NDUB1_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; AltName: Full=Complex I-MNLL; Short=CI-MNLL; AltName: Full=NADH-ubiquinone oxidoreductase MNLL subunit;+++[A0A024R6G6_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase (Ubiquinone) 1 beta subcomplex, 1, 7kDa, isoform CRA_a {ECO:0000313|EMBL:EAW81477.1};+++[Q3MHU6_HUMAN|Unreviewed]SubName: Full=NDUFB1 protein {ECO:0000313|EMBL:AAI04673.1}; Flags: Fragment;"]
[4723,"'NDUFV1'",1256,1353,1347,1318.66666666667,"01100///Metabolic pathways+++00190///Oxidative phosphorylation+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04723///Retrograde endocannabinoid signaling+++04714///Thermogenesis+++05016///Huntington's disease+++05010///Alzheimer's disease","H00473///Mitochondrial complex I deficiency","M00143///NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria","R11945///NADH:ubiquinone oxidoreductase   Ubiquinone + NADH + 6 H+ <=> Ubiquinol + NAD+ + 5 H+","GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane+++GO:0070469///respiratory chain+++GO:0005739///mitochondrion+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0016020///membrane","GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0051287///NAD binding+++GO:0046872///metal ion binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0010181///FMN binding+++GO:0051536///iron-sulfur cluster binding+++GO:0003954///NADH dehydrogenase activity+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity","GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0055114///oxidation-reduction process","NADH:ubiquinone oxidoreductase core subunit V1","[NDUV1_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; EC=1.6.5.3; EC=1.6.99.3; AltName: Full=Complex I-51kD; Short=CI-51kD; AltName: Full=NADH dehydrogenase flavoprotein 1; AltName: Full=NADH-ubiquinone oxidoreductase 51 kDa subunit; Flags: Precursor;+++[B4DE93_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000432015}; SubName: Full=cDNA FLJ57949, highly similar to NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial {ECO:0000313|EMBL:BAG57004.1}; SubName: Full=cDNA, FLJ79021, highly similar to NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial {ECO:0000313|EMBL:BAH14493.1};+++[E5KNH5_HUMAN|Unreviewed]RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000256|RuleBase:RU364066}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU364066}; EC=1.6.99.3 {ECO:0000256|RuleBase:RU364066};+++[E9PJL9_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000431751}; Flags: Fragment;+++[E9PLC6_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000435202}; Flags: Fragment;+++[E9PMX3_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000437267}; Flags: Fragment;+++[E9PPD6_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000434581}; Flags: Fragment;+++[E9PPE0_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000434575};+++[E9PPR0_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000436936}; Flags: Fragment;+++[E9PPS5_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000436906}; Flags: Fragment;+++[E9PQP1_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000434438}; Flags: Fragment;+++[G3V0I5_HUMAN|Unreviewed]RecName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000256|RuleBase:RU364066}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU364066}; EC=1.6.99.3 {ECO:0000256|RuleBase:RU364066};+++[H0YD04_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000432637}; Flags: Fragment;+++[H0YE81_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000435199}; Flags: Fragment;"]
[474170,"'LRRC37A2'",370.09,295.14,332.08,332.436666666667,"04138///Autophagy - yeast+++04140///Autophagy - animal+++04727///GABAergic synapse+++03010///Ribosome+++04962///Vasopressin-regulated water reabsorption+++04721///Synaptic vesicle cycle+++04137///Mitophagy - animal","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003735///structural constituent of ribosome","GO:0030154///cell differentiation+++GO:0002181///cytoplasmic translation+++GO:0001843///neural tube closure+++GO:0006364///rRNA processing+++GO:0042274///ribosomal small subunit biogenesis","leucine rich repeat containing 37 member A2","[L37A2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 37A2; Flags: Precursor;+++[A0A0G2JNP1_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A2 {ECO:0000313|Ensembl:ENSP00000481827};+++[A0A0G2JP19_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A2 {ECO:0000313|Ensembl:ENSP00000482650};+++[A0A0G2JRA3_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A2 {ECO:0000313|Ensembl:ENSP00000486567};+++[A0A0G2JS48_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A2 {ECO:0000313|Ensembl:ENSP00000487340};+++[A0A0J9YVP4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A2 {ECO:0000313|Ensembl:ENSP00000487612};+++[A0A0J9YVT7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A2 {ECO:0000313|Ensembl:ENSP00000487663};+++[A0A0J9YWT4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 37A2 {ECO:0000313|Ensembl:ENSP00000488106};+++[B7ZMC4_HUMAN|Unreviewed]SubName: Full=LRRC37A2 protein {ECO:0000313|EMBL:AAI44429.1}; Flags: Fragment;+++[Q5YKG5_HUMAN|Unreviewed]SubName: Full=C114 SLIT-like testicular protein {ECO:0000313|EMBL:AAR28083.1};"]
[4771,"'NF2'",1475.03,1535,1379,1463.01,"04390///Hippo signaling pathway+++04530///Tight junction+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species","H01438///Neurofibromatosis type 2+++H01667///Medulloblastoma+++H01556///Meningioma+++H00015///Malignant pleural mesothelioma","M00683///Hippo signaling",null,"GO:0016020///membrane+++GO:0030175///filopodium+++GO:0005856///cytoskeleton+++GO:0045177///apical part of cell+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0032154///cleavage furrow+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005912///adherens junction+++GO:0044297///cell body+++GO:0001726///ruffle+++GO:0005769///early endosome+++GO:0032587///ruffle membrane+++GO:0005575///cellular_component+++GO:0031527///filopodium membrane+++GO:0043005///neuron projection+++GO:0030027///lamellipodium+++GO:0030864///cortical actin cytoskeleton+++GO:0048471///perinuclear region of cytoplasm","GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding","GO:0001707///mesoderm formation+++GO:0045597///positive regulation of cell differentiation+++GO:0021766///hippocampus development+++GO:0008150///biological_process+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0070306///lens fiber cell differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:0051496///positive regulation of stress fiber assembly+++GO:0042127///regulation of cell proliferation+++GO:0043409///negative regulation of MAPK cascade+++GO:0045216///cell-cell junction organization+++GO:0051726///regulation of cell cycle+++GO:0042981///regulation of apoptotic process+++GO:1900180///regulation of protein localization to nucleus+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0031647///regulation of protein stability+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0014013///regulation of gliogenesis+++GO:0072091///regulation of stem cell proliferation+++GO:0014010///Schwann cell proliferation+++GO:0030336///negative regulation of cell migration+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:2000177///regulation of neural precursor cell proliferation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0050767///regulation of neurogenesis+++GO:0035330///regulation of hippo signaling+++GO:0030036///actin cytoskeleton organization+++GO:0007398///ectoderm development+++GO:0006469///negative regulation of protein kinase activity+++GO:0007420///brain development","neurofibromin 2","[MERL_HUMAN|Reviewed]RecName: Full=Merlin; AltName: Full=Moesin-ezrin-radixin-like protein; AltName: Full=Neurofibromin-2; AltName: Full=Schwannomerlin; AltName: Full=Schwannomin;+++[A0A024R1D9_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 (Bilateral acoustic neuroma), isoform CRA_d {ECO:0000313|EMBL:EAW59831.1};+++[A0A024R1F6_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 (Bilateral acoustic neuroma), isoform CRA_i {ECO:0000313|EMBL:EAW59830.1};+++[A0A024R1I0_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 (Bilateral acoustic neuroma), isoform CRA_g {ECO:0000313|EMBL:EAW59828.1};+++[A0A024R1J8_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 (Bilateral acoustic neuroma), isoform CRA_a {ECO:0000313|EMBL:EAW59824.1};+++[A0A024R1J9_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 (Bilateral acoustic neuroma), isoform CRA_e {ECO:0000313|EMBL:EAW59829.1};+++[A0A286SD19_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 {ECO:0000313|EMBL:ASZ70033.1}; Flags: Fragment;+++[A0A286SD20_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 {ECO:0000313|EMBL:ASZ70034.1}; Flags: Fragment;+++[A0A286SD34_HUMAN|Unreviewed]SubName: Full=Neurofibromin 2 {ECO:0000313|EMBL:ASZ70035.1}; Flags: Fragment;+++[A5A158_HUMAN|Unreviewed]SubName: Full=Merlin variant 14 {ECO:0000313|EMBL:ABP73252.1};+++[Q16230_HUMAN|Unreviewed]SubName: Full=NF2 protein {ECO:0000313|EMBL:AAB31736.1}; Flags: Fragment;+++[Q16231_HUMAN|Unreviewed]SubName: Full=NF2 protein {ECO:0000313|EMBL:AAB31737.1}; Flags: Fragment;+++[Q16232_HUMAN|Unreviewed]SubName: Full=NF2 protein {ECO:0000313|EMBL:AAD14139.1}; Flags: Fragment;+++[Q16233_HUMAN|Unreviewed]SubName: Full=NF2 protein {ECO:0000313|EMBL:AAB31738.1}; Flags: Fragment;+++[Q16276_HUMAN|Unreviewed]SubName: Full=Neurofibromatosis type 2 {ECO:0000313|EMBL:AAD14190.2}; Flags: Fragment;+++[Q7KZ66_HUMAN|Unreviewed]SubName: Full=NF2 protein {ECO:0000313|EMBL:AAA62422.1}; Flags: Fragment;+++[Q9NRW8_HUMAN|Unreviewed]SubName: Full=Neurofibromatosis type 2 {ECO:0000313|EMBL:AAF80764.1}; Flags: Fragment;"]
[4790,"'NFKB1'",191,221,166,192.666666666667,"05169///Epstein-Barr virus infection+++05418///Fluid shear stress and atherosclerosis+++05221///Acute myeloid leukemia+++05220///Chronic myeloid leukemia+++04662///B cell receptor signaling pathway+++04024///cAMP signaling pathway+++04722///Neurotrophin signaling pathway+++05162///Measles+++05140///Leishmaniasis+++04210///Apoptosis+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04625///C-type lectin receptor signaling pathway+++05215///Prostate cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++04014///Ras signaling pathway+++05166///HTLV-I infection+++05030///Cocaine addiction+++04623///Cytosolic DNA-sensing pathway+++05200///Pathways in cancer+++05222///Small cell lung cancer+++04622///RIG-I-like receptor signaling pathway+++04917///Prolactin signaling pathway+++04071///Sphingolipid signaling pathway+++04660///T cell receptor signaling pathway+++05203///Viral carcinogenesis+++04064///NF-kappa B signaling pathway+++04920///Adipocytokine signaling pathway+++04668///TNF signaling pathway+++05132///Salmonella infection+++05134///Legionellosis+++05321///Inflammatory bowel disease (IBD)+++04010///MAPK signaling pathway+++05164///Influenza A+++04066///HIF-1 signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++05212///Pancreatic cancer+++04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++05131///Shigellosis+++05160///Hepatitis C+++04620///Toll-like receptor signaling pathway+++05165///Human papillomavirus infection+++05163///Human cytomegalovirus infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05145///Toxoplasmosis+++05206///MicroRNAs in cancer+++04218///Cellular senescence+++04657///IL-17 signaling pathway+++04621///NOD-like receptor signaling pathway+++04926///Relaxin signaling pathway+++04380///Osteoclast differentiation+++05146///Amoebiasis+++05133///Pertussis+++05202///Transcriptional misregulation in cancer+++04624///Toll and Imd signaling pathway+++04211///Longevity regulating pathway+++05161///Hepatitis B+++05152///Tuberculosis+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01523///Antifolate resistance+++04931///Insulin resistance+++05168///Herpes simplex infection",null,"M00686///Toll-like receptor signaling",null,"GO:0005634///nucleus+++GO:0035580///specific granule lumen+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0034774///secretory granule lumen+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0033256///I-kappaB/NF-kappaB complex","GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0042802///identical protein binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0042805///actinin binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0008134///transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0071359///cellular response to dsRNA+++GO:0035994///response to muscle stretch+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071347///cellular response to interleukin-1+++GO:0071316///cellular response to nicotine+++GO:0006915///apoptotic process+++GO:0051403///stress-activated MAPK cascade+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032375///negative regulation of cholesterol transport+++GO:0010956///negative regulation of calcidiol 1-monooxygenase activity+++GO:0007165///signal transduction+++GO:0071260///cellular response to mechanical stimulus+++GO:0006366///transcription by RNA polymerase II+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0010957///negative regulation of vitamin D biosynthetic process+++GO:0010629///negative regulation of gene expression+++GO:0071354///cellular response to interleukin-6+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0032481///positive regulation of type I interferon production+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0043066///negative regulation of apoptotic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0050728///negative regulation of inflammatory response+++GO:2000630///positive regulation of miRNA metabolic process+++GO:0045083///negative regulation of interleukin-12 biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010884///positive regulation of lipid storage+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1900127///positive regulation of hyaluronan biosynthetic process+++GO:0050852///T cell receptor signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:1904385///cellular response to angiotensin+++GO:0032269///negative regulation of cellular protein metabolic process+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0001818///negative regulation of cytokine production+++GO:0006954///inflammatory response+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","nuclear factor kappa B subunit 1","[NFKB1_HUMAN|Reviewed]RecName: Full=Nuclear factor NF-kappa-B p105 subunit; AltName: Full=DNA-binding factor KBF1; AltName: Full=EBP-1; AltName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; Contains: RecName: Full=Nuclear factor NF-kappa-B p50 subunit;+++[A0A024RDJ4_HUMAN|Unreviewed]SubName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (P105), isoform CRA_b {ECO:0000313|EMBL:EAX06136.1};+++[D6RC45_HUMAN|Unreviewed]SubName: Full=Nuclear factor NF-kappa-B p105 subunit {ECO:0000313|Ensembl:ENSP00000423877}; Flags: Fragment;+++[D6RDI9_HUMAN|Unreviewed]SubName: Full=Nuclear factor NF-kappa-B p105 subunit {ECO:0000313|Ensembl:ENSP00000420904}; Flags: Fragment;+++[D6RF93_HUMAN|Unreviewed]SubName: Full=Nuclear factor NF-kappa-B p105 subunit {ECO:0000313|Ensembl:ENSP00000424815}; Flags: Fragment;+++[D6RH30_HUMAN|Unreviewed]SubName: Full=Nuclear factor NF-kappa-B p105 subunit {ECO:0000313|Ensembl:ENSP00000426147}; Flags: Fragment;"]
[4810,"'NHS'",74,34,42,50,{"$nulls":4},"GO:0005923///bicellular tight junction+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005925///focal adhesion+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0016604///nuclear body+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0030027///lamellipodium","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0009653///anatomical structure morphogenesis+++GO:0002088///lens development in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation","NHS actin remodeling regulator","[NHS_HUMAN|Reviewed]RecName: Full=Nance-Horan syndrome protein; AltName: Full=Congenital cataracts and dental anomalies protein;+++[A0A087WU78_HUMAN|Unreviewed]SubName: Full=Nance-Horan syndrome protein {ECO:0000313|Ensembl:ENSP00000478433};+++[A0A087WWC4_HUMAN|Unreviewed]SubName: Full=Nance-Horan syndrome protein {ECO:0000313|Ensembl:ENSP00000480113};"]
[483,"'ATP1B3'",1713,1825,1310,1616,"04961///Endocrine and other factor-regulated calcium reabsorption+++04911///Insulin secretion+++04919///Thyroid hormone signaling pathway+++04971///Gastric acid secretion+++04261///Adrenergic signaling in cardiomyocytes+++04964///Proximal tubule bicarbonate reclamation+++04960///Aldosterone-regulated sodium reabsorption+++04918///Thyroid hormone synthesis+++04970///Salivary secretion+++04974///Protein digestion and absorption+++04978///Mineral absorption+++04024///cAMP signaling pathway+++04973///Carbohydrate digestion and absorption+++04976///Bile secretion+++04925///Aldosterone synthesis and secretion+++04972///Pancreatic secretion+++04022///cGMP-PKG signaling pathway+++04260///Cardiac muscle contraction",{"$nulls":3},"GO:0016020///membrane+++GO:0042470///melanosome+++GO:0016021///integral component of membrane+++GO:0005901///caveola+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0005886///plasma membrane","GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0051117///ATPase binding+++GO:0001671///ATPase activator activity","GO:0050821///protein stabilization+++GO:0030007///cellular potassium ion homeostasis+++GO:1903288///positive regulation of potassium ion import+++GO:0006883///cellular sodium ion homeostasis+++GO:0006811///ion transport+++GO:1903278///positive regulation of sodium ion export across plasma membrane+++GO:0050900///leukocyte migration+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:0036376///sodium ion export across plasma membrane+++GO:1990573///potassium ion import across plasma membrane+++GO:0006813///potassium ion transport+++GO:0006814///sodium ion transport+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0030001///metal ion transport+++GO:0072659///protein localization to plasma membrane+++GO:0086009///membrane repolarization+++GO:0032781///positive regulation of ATPase activity","ATPase Na+/K+ transporting subunit beta 3","[AT1B3_HUMAN|Reviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta-3; AltName: Full=Sodium/potassium-dependent ATPase subunit beta-3; Short=ATPB-3; AltName: CD_antigen=CD298;+++[C9J6S2_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-3 {ECO:0000313|Ensembl:ENSP00000418353};+++[C9JA36_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-3 {ECO:0000313|Ensembl:ENSP00000417522}; Flags: Fragment;+++[C9JXZ1_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-3 {ECO:0000313|Ensembl:ENSP00000419962}; Flags: Fragment;+++[D3DNF9_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};+++[F8WBY4_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-3 {ECO:0000313|Ensembl:ENSP00000418280};+++[H7C4L9_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-3 {ECO:0000313|Ensembl:ENSP00000417608}; Flags: Fragment;+++[H7C547_HUMAN|Unreviewed]SubName: Full=Sodium/potassium-transporting ATPase subunit beta-3 {ECO:0000313|Ensembl:ENSP00000418952}; Flags: Fragment;+++[Q58I18_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099}; Flags: Fragment;"]
[4852,"'NPY'",2,0,5,2.33333333333333,"04024///cAMP signaling pathway+++04923///Regulation of lipolysis in adipocytes+++05034///Alcoholism+++04920///Adipocytokine signaling pathway",{"$nulls":3},"GO:0005623///cell+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0005102///signaling receptor binding+++GO:0001664///G protein-coupled receptor binding+++GO:0005246///calcium channel regulator activity+++GO:0031841///neuropeptide Y receptor binding+++GO:0005179///hormone activity+++GO:0005184///neuropeptide hormone activity+++GO:0004930///G protein-coupled receptor activity","GO:0021987///cerebral cortex development+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0010469///regulation of signaling receptor activity+++GO:0008217///regulation of blood pressure+++GO:0031175///neuron projection development+++GO:0021954///central nervous system neuron development+++GO:0007631///feeding behavior+++GO:0032100///positive regulation of appetite+++GO:0008283///cell proliferation+++GO:0007268///chemical synaptic transmission+++GO:0045087///innate immune response+++GO:0008343///adult feeding behavior+++GO:0007218///neuropeptide signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006816///calcium ion transport+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide","neuropeptide Y","[NPY_HUMAN|Reviewed]RecName: Full=Pro-neuropeptide Y; Contains: RecName: Full=Neuropeptide Y; AltName: Full=Neuropeptide tyrosine; Short=NPY; Contains: RecName: Full=C-flanking peptide of NPY; Short=CPON; Flags: Precursor;+++[A4D158_HUMAN|Unreviewed]SubName: Full=Neuropeptide Y {ECO:0000313|EMBL:EAL24248.1}; SubName: Full=cDNA, FLJ92442, Homo sapiens neuropeptide Y (NPY), mRNA {ECO:0000313|EMBL:BAG35090.1};"]
[4882,"'NPR2'",409,443,453,435,"04270///Vascular smooth muscle contraction+++00230///Purine metabolism+++04022///cGMP-PKG signaling pathway+++04921///Oxytocin signaling pathway","H00470///Acromesomelic dysplasia, Maroteaux type","M00694///cGMP signaling","R00434///GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)   GTP <=> 3',5'-Cyclic GMP + Diphosphate","GO:0032991///protein-containing complex+++GO:0001726///ruffle+++GO:0008074///guanylate cyclase complex, soluble+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0032587///ruffle membrane+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0032588///trans-Golgi network membrane+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0034066///RIC1-RGP1 guanyl-nucleotide exchange factor complex","GO:0017166///vinculin binding+++GO:0042562///hormone binding+++GO:0004672///protein kinase activity+++GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0045296///cadherin binding+++GO:0030274///LIM domain binding+++GO:0035091///phosphatidylinositol binding+++GO:0042802///identical protein binding+++GO:0005178///integrin binding+++GO:0005524///ATP binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0017046///peptide hormone binding+++GO:0004383///guanylate cyclase activity+++GO:0005525///GTP binding+++GO:0017137///Rab GTPase binding+++GO:0051015///actin filament binding+++GO:0001786///phosphatidylserine binding+++GO:0016941///natriuretic peptide receptor activity","GO:0022414///reproductive process+++GO:1903779///regulation of cardiac conduction+++GO:0070527///platelet aggregation+++GO:0007043///cell-cell junction assembly+++GO:0007229///integrin-mediated signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0008217///regulation of blood pressure+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0007016///cytoskeletal anchoring at plasma membrane+++GO:0007044///cell-substrate junction assembly+++GO:0002576///platelet degranulation+++GO:0019934///cGMP-mediated signaling+++GO:0051447///negative regulation of meiotic cell cycle+++GO:0001503///ossification+++GO:0030866///cortical actin cytoskeleton organization+++GO:0006936///muscle contraction+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0060348///bone development+++GO:0033622///integrin activation+++GO:1900194///negative regulation of oocyte maturation+++GO:0016032///viral process+++GO:1903363///negative regulation of cellular protein catabolic process+++GO:0006182///cGMP biosynthetic process+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus","natriuretic peptide receptor 2","[ANPRB_HUMAN|Reviewed]RecName: Full=Atrial natriuretic peptide receptor 2; EC=4.6.1.2 {ECO:0000269|PubMed:26980729}; AltName: Full=Atrial natriuretic peptide receptor type B; Short=ANP-B; Short=ANPR-B; Short=NPR-B; AltName: Full=Guanylate cyclase B; Short=GC-B; Flags: Precursor;"]
[4898,"'NRDC'",1805,1638,1512,1651.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0005739///mitochondrion","GO:0048408///epidermal growth factor binding+++GO:0046872///metal ion binding+++GO:0008237///metallopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0003824///catalytic activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0007528///neuromuscular junction development+++GO:0006508///proteolysis+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0016477///cell migration+++GO:0008283///cell proliferation+++GO:0052548///regulation of endopeptidase activity","nardilysin convertase","[NRDC_HUMAN|Reviewed]RecName: Full=Nardilysin; EC=3.4.24.61; AltName: Full=N-arginine dibasic convertase; Short=NRD convertase; Short=NRD-C; AltName: Full=Nardilysin convertase {ECO:0000312|HGNC:HGNC:7995}; Flags: Precursor;+++[B1AKJ5_HUMAN|Unreviewed]SubName: Full=Nardilysin (N-arginine dibasic convertase), isoform CRA_d {ECO:0000313|EMBL:EAX06807.1};+++[F5H7V1_HUMAN|Unreviewed]SubName: Full=Nardilysin {ECO:0000313|Ensembl:ENSP00000442262};+++[G3V1R5_HUMAN|Unreviewed]SubName: Full=Nardilysin {ECO:0000313|Ensembl:ENSP00000444416}; SubName: Full=Nardilysin (N-arginine dibasic convertase), isoform CRA_e {ECO:0000313|EMBL:EAX06808.1};+++[H0Y5G9_HUMAN|Unreviewed]SubName: Full=Nardilysin {ECO:0000313|Ensembl:ENSP00000398464}; Flags: Fragment;+++[Q6UUU9_HUMAN|Unreviewed]SubName: Full=Nardilysin isoform {ECO:0000313|EMBL:AAQ63406.1};+++[Q96L67_HUMAN|Unreviewed]SubName: Full=Nardilysin {ECO:0000313|EMBL:AAL15441.1};"]
[4922,"'NTS'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0005576///extracellular region+++GO:0030133///transport vesicle+++GO:0043679///axon terminus","GO:0005515///protein binding+++GO:0005184///neuropeptide hormone activity","GO:0007165///signal transduction+++GO:0050880///regulation of blood vessel size+++GO:0010469///regulation of signaling receptor activity+++GO:0007186///G protein-coupled receptor signaling pathway","neurotensin","[NEUT_HUMAN|Reviewed]RecName: Full=Neurotensin/neuromedin N; Contains: RecName: Full=Large neuromedin N; AltName: Full=NmN-125; Contains: RecName: Full=Neuromedin N; Short=NN; Short=NmN; Contains: RecName: Full=Neurotensin; Short=NT; Contains: RecName: Full=Tail peptide; Flags: Precursor;+++[G3V1X6_HUMAN|Unreviewed]SubName: Full=Neurotensin, isoform CRA_a {ECO:0000313|EMBL:EAW97400.1}; SubName: Full=Neurotensin/neuromedin N {ECO:0000313|Ensembl:ENSP00000448328};+++[Q6FH20_HUMAN|Unreviewed]SubName: Full=NTS protein {ECO:0000313|EMBL:CAG46734.1}; SubName: Full=Neurotensin, isoform CRA_b {ECO:0000313|EMBL:EAW97401.1}; SubName: Full=Preproneurotensin/neuromedin N {ECO:0000313|EMBL:AAP37614.1}; SubName: Full=cDNA, FLJ92347, Homo sapiens neurotensin (NTS), mRNA {ECO:0000313|EMBL:BAG35002.1};"]
[4929,"'NR4A2'",5,4,1,3.33333333333333,"04928///Parathyroid hormone synthesis, secretion and action+++04925///Aldosterone synthesis and secretion","H00057///Parkinson's disease (PD)",null,null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0003707///steroid hormone receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0008013///beta-catenin binding+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0035259///glucocorticoid receptor binding","GO:0021952///central nervous system projection neuron axonogenesis+++GO:0008344///adult locomotory behavior+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0001666///response to hypoxia+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0010467///gene expression+++GO:0043085///positive regulation of catalytic activity+++GO:0006351///transcription, DNA-templated+++GO:0042416///dopamine biosynthetic process+++GO:0071542///dopaminergic neuron differentiation+++GO:0042551///neuron maturation+++GO:0001975///response to amphetamine+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045444///fat cell differentiation+++GO:0009791///post-embryonic development+++GO:0034599///cellular response to oxidative stress+++GO:0001764///neuron migration+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:0042417///dopamine metabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0060070///canonical Wnt signaling pathway+++GO:0021953///central nervous system neuron differentiation+++GO:0007165///signal transduction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:0042053///regulation of dopamine metabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0021986///habenula development+++GO:0010468///regulation of gene expression+++GO:0031668///cellular response to extracellular stimulus+++GO:0007399///nervous system development+++GO:0030182///neuron differentiation+++GO:0051866///general adaptation syndrome+++GO:0006355///regulation of transcription, DNA-templated","nuclear receptor subfamily 4 group A member 2","[NR4A2_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 4 group A member 2; AltName: Full=Immediate-early response protein NOT; AltName: Full=Orphan nuclear receptor NURR1; AltName: Full=Transcriptionally-inducible nuclear receptor;+++[A0A0S2Z418_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 isoform 2 {ECO:0000313|EMBL:ALQ33697.1}; Flags: Fragment;+++[C0KWD1_HUMAN|Unreviewed]SubName: Full=Orphan nuclear receptor NR4A2 isoform 1 {ECO:0000313|EMBL:ACN32470.1}; Flags: Fragment;+++[C0KWD2_HUMAN|Unreviewed]SubName: Full=Orphan nuclear receptor NR4A2 isoform 2 {ECO:0000313|EMBL:ACN32471.1}; Flags: Fragment;+++[C9IYM5_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000406808}; Flags: Fragment;+++[C9J8W4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000410952};+++[C9JWQ1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000388120}; Flags: Fragment;+++[E9PBQ4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000415632};+++[F1D8N6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor related 1 {ECO:0000313|EMBL:ADZ17335.1}; SubName: Full=Nuclear receptor subfamily 4 group A member 2 isoform 1 {ECO:0000313|EMBL:ALQ33696.1};+++[F1DAL2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor related 1 {ECO:0000313|EMBL:ADZ17383.1};+++[F8W6I3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000386993};+++[H7BZ00_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000385379}; Flags: Fragment;+++[Q53EL4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4, group A, member 2 isoform a variant {ECO:0000313|EMBL:BAD97345.1}; Flags: Fragment;"]
[495,"'ATP4A'",0,1,0,0.333333333333333,"00190///Oxidative phosphorylation+++04966///Collecting duct acid secretion+++04971///Gastric acid secretion",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008900///potassium:proton exchanging ATPase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding","GO:0030007///cellular potassium ion homeostasis+++GO:0006813///potassium ion transport+++GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0006814///sodium ion transport+++GO:0036376///sodium ion export across plasma membrane+++GO:0006811///ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0015991///ATP hydrolysis coupled proton transport+++GO:0006883///cellular sodium ion homeostasis","ATPase H+/K+ transporting subunit alpha","[ATP4A_HUMAN|Reviewed]RecName: Full=Potassium-transporting ATPase alpha chain 1; EC=3.6.3.10; AltName: Full=Gastric H(+)/K(+) ATPase subunit alpha; AltName: Full=Proton pump;+++[M0R249_HUMAN|Unreviewed]SubName: Full=Potassium-transporting ATPase alpha chain 1 {ECO:0000313|Ensembl:ENSP00000472323}; Flags: Fragment;+++[Q658V6_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit alpha {ECO:0000256|RuleBase:RU362084}; EC=3.6.3.- {ECO:0000256|RuleBase:RU362084}; Flags: Fragment;"]
[497190,"'CLEC18B'",182.91,179.55,137.73,166.73,{"$nulls":4},"GO:0016529///sarcoplasmic reticulum+++GO:0005783///endoplasmic reticulum+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005794///Golgi apparatus","GO:0030247///polysaccharide binding+++GO:0030246///carbohydrate binding",null,"C-type lectin domain family 18 member B","[CL18B_HUMAN|Reviewed]RecName: Full=C-type lectin domain family 18 member B; AltName: Full=Mannose receptor-like protein 1; Flags: Precursor;+++[A0A087WT46_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 18 member B {ECO:0000313|Ensembl:ENSP00000477577};+++[A0A087X0Q5_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 18 member B {ECO:0000313|Ensembl:ENSP00000483587};"]
[4985,"'OPRD1'",2,0,1,1,"04022///cGMP-PKG signaling pathway+++04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction","H01703///Eating Disorders",null,null,"GO:0098992///neuronal dense core vesicle+++GO:0016021///integral component of membrane+++GO:0043679///axon terminus+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0032590///dendrite membrane+++GO:0045121///membrane raft+++GO:0031226///intrinsic component of plasma membrane+++GO:0031982///vesicle+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0005737///cytoplasm+++GO:0099056///integral component of presynaptic membrane+++GO:0097444///spine apparatus","GO:0038046///enkephalin receptor activity+++GO:0005515///protein binding+++GO:0004930///G protein-coupled receptor activity+++GO:0033612///receptor serine/threonine kinase binding+++GO:0042923///neuropeptide binding+++GO:0004985///opioid receptor activity","GO:0019221///cytokine-mediated signaling pathway+++GO:0051924///regulation of calcium ion transport+++GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0032460///negative regulation of protein oligomerization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0097237///cellular response to toxic substance+++GO:0007218///neuropeptide signaling pathway+++GO:0038003///opioid receptor signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0008344///adult locomotory behavior+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0071456///cellular response to hypoxia+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0000060///protein import into nucleus, translocation+++GO:0071363///cellular response to growth factor stimulus+++GO:0051930///regulation of sensory perception of pain+++GO:0042755///eating behavior","opioid receptor delta 1","[OPRD_HUMAN|Reviewed]RecName: Full=Delta-type opioid receptor; Short=D-OR-1; Short=DOR-1;+++[D2CGC9_HUMAN|Unreviewed]SubName: Full=Delta opioid receptor 1 variant {ECO:0000313|EMBL:ABO25742.1}; SubName: Full=Delta-type opioid receptor {ECO:0000313|Ensembl:ENSP00000477970};"]
[5013,"'OTX1'",205,246,226,225.666666666667,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0042472///inner ear morphogenesis+++GO:0030900///forebrain development+++GO:0030901///midbrain development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0009952///anterior/posterior pattern specification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0048852///diencephalon morphogenesis+++GO:0022037///metencephalon development","orthodenticle homeobox 1","[OTX1_HUMAN|Reviewed]RecName: Full=Homeobox protein OTX1; AltName: Full=Orthodenticle homolog 1;+++[B5MC54_HUMAN|Unreviewed]SubName: Full=Homeobox protein OTX1 {ECO:0000313|Ensembl:ENSP00000385782};+++[D6W5E5_HUMAN|Unreviewed]SubName: Full=Orthodenticle homolog 1 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW99968.1};+++[Q9P2R2_HUMAN|Unreviewed]SubName: Full=Homeobox protein OTX1 {ECO:0000313|EMBL:BAA90421.1}; Flags: Fragment;"]
[5028,"'P2RY1'",5,5,14,8,"04742///Taste transduction+++04611///Platelet activation+++04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0045211///postsynaptic membrane+++GO:0016324///apical plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0014069///postsynaptic density+++GO:0044297///cell body+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0030425///dendrite","GO:0004930///G protein-coupled receptor activity+++GO:0000166///nucleotide binding+++GO:0043531///ADP binding+++GO:0046982///protein heterodimerization activity+++GO:0097110///scaffold protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0031686///A1 adenosine receptor binding+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0045032///ADP-activated adenosine receptor activity+++GO:0038023///signaling receptor activity+++GO:0045031///ATP-activated adenosine receptor activity","GO:0010700///negative regulation of norepinephrine secretion+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0097746///regulation of blood vessel diameter+++GO:0042755///eating behavior+++GO:0071318///cellular response to ATP+++GO:0072659///protein localization to plasma membrane+++GO:0071415///cellular response to purine-containing compound+++GO:0019233///sensory perception of pain+++GO:0008360///regulation of cell shape+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0042060///wound healing+++GO:0060406///positive regulation of penile erection+++GO:0001973///adenosine receptor signaling pathway+++GO:0046887///positive regulation of hormone secretion+++GO:0043270///positive regulation of ion transport+++GO:0007596///blood coagulation+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0008347///glial cell migration+++GO:0007599///hemostasis+++GO:0051100///negative regulation of binding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010469///regulation of signaling receptor activity+++GO:0030168///platelet activation+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0090075///relaxation of muscle+++GO:0007568///aging+++GO:0007165///signal transduction+++GO:0071407///cellular response to organic cyclic compound+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0009612///response to mechanical stimulus+++GO:0070848///response to growth factor","purinergic receptor P2Y1","[P2RY1_HUMAN|Reviewed]RecName: Full=P2Y purinoceptor 1; Short=P2Y1; AltName: Full=ADP receptor {ECO:0000303|PubMed:9038354}; AltName: Full=Purinergic receptor;"]
[5050,"'PAFAH1B3'",416,400,386,400.666666666667,"00565///Ether lipid metabolism+++01100///Metabolic pathways",null,null,"R04452///1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine acetohydrolase   2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Acetate","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0016787///hydrolase activity+++GO:0003847///1-alkyl-2-acetylglycerophosphocholine esterase activity+++GO:0004623///phospholipase A2 activity+++GO:0005515///protein binding+++GO:0047179///platelet-activating factor acetyltransferase activity+++GO:0042802///identical protein binding","GO:0007283///spermatogenesis+++GO:0016042///lipid catabolic process+++GO:0007399///nervous system development+++GO:0006629///lipid metabolic process+++GO:0007420///brain development","platelet activating factor acetylhydrolase 1b catalytic subunit 3","[PA1B3_HUMAN|Reviewed]RecName: Full=Platelet-activating factor acetylhydrolase IB subunit gamma; EC=3.1.1.47; AltName: Full=PAF acetylhydrolase 29 kDa subunit; Short=PAF-AH 29 kDa subunit; AltName: Full=PAF-AH subunit gamma; Short=PAFAH subunit gamma;+++[A0A024R0L6_HUMAN|Unreviewed]SubName: Full=Platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa, isoform CRA_a {ECO:0000313|EMBL:EAW57125.1};+++[M0QXS6_HUMAN|Unreviewed]SubName: Full=Platelet-activating factor acetylhydrolase IB subunit gamma {ECO:0000313|Ensembl:ENSP00000469352}; Flags: Fragment;+++[M0QZT2_HUMAN|Unreviewed]SubName: Full=Platelet-activating factor acetylhydrolase IB subunit gamma {ECO:0000313|Ensembl:ENSP00000470753}; Flags: Fragment;+++[M0R1K3_HUMAN|Unreviewed]SubName: Full=Platelet-activating factor acetylhydrolase IB subunit gamma {ECO:0000313|Ensembl:ENSP00000471933}; Flags: Fragment;+++[M0R323_HUMAN|Unreviewed]SubName: Full=Platelet-activating factor acetylhydrolase IB subunit gamma {ECO:0000313|Ensembl:ENSP00000472950}; Flags: Fragment;+++[M0R389_HUMAN|Unreviewed]SubName: Full=Platelet-activating factor acetylhydrolase IB subunit gamma {ECO:0000313|Ensembl:ENSP00000473065}; Flags: Fragment;"]
[506,"'ATP5F1B'",4872,5018,5263,5051,"00190///Oxidative phosphorylation+++05016///Huntington's disease+++05012///Parkinson's disease+++05010///Alzheimer's disease+++04714///Thermogenesis+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0070062///extracellular exosome+++GO:0005759///mitochondrial matrix+++GO:0005743///mitochondrial inner membrane+++GO:0005886///plasma membrane+++GO:0045259///proton-transporting ATP synthase complex+++GO:0042645///mitochondrial nucleoid+++GO:0005739///mitochondrion+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0043209///myelin sheath+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0005754///mitochondrial proton-transporting ATP synthase, catalytic core+++GO:0031966///mitochondrial membrane","GO:0005524///ATP binding+++GO:0043532///angiostatin binding+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0042288///MHC class I protein binding+++GO:0022857///transmembrane transporter activity+++GO:0005215///transporter activity+++GO:0005515///protein binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism","GO:0098761///cellular response to interleukin-7+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0001649///osteoblast differentiation+++GO:0006091///generation of precursor metabolites and energy+++GO:0006629///lipid metabolic process+++GO:0006754///ATP biosynthetic process+++GO:1902600///proton transmembrane transport+++GO:0006811///ion transport+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0006933///negative regulation of cell adhesion involved in substrate-bound cell migration+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0046034///ATP metabolic process+++GO:0051453///regulation of intracellular pH+++GO:0042407///cristae formation+++GO:0001525///angiogenesis+++GO:0007005///mitochondrion organization","ATP synthase F1 subunit beta","[ATPB_HUMAN|Reviewed]RecName: Full=ATP synthase subunit beta, mitochondrial {ECO:0000305}; EC=3.6.3.14; AltName: Full=ATP synthase F1 subunit beta {ECO:0000312|HGNC:HGNC:830}; Flags: Precursor;+++[F8W079_HUMAN|Unreviewed]SubName: Full=ATP synthase subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000446677}; Flags: Fragment;+++[F8W0P7_HUMAN|Unreviewed]SubName: Full=ATP synthase subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000447571}; Flags: Fragment;+++[H0YH81_HUMAN|Unreviewed]RecName: Full=ATP synthase subunit beta {ECO:0000256|RuleBase:RU003553}; EC=3.6.3.14 {ECO:0000256|RuleBase:RU003553}; Flags: Fragment;+++[H0YI37_HUMAN|Unreviewed]SubName: Full=ATP synthase subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000448428}; Flags: Fragment;+++[Q0QEN7_HUMAN|Unreviewed]RecName: Full=ATP synthase subunit beta {ECO:0000256|RuleBase:RU003553}; EC=3.6.3.14 {ECO:0000256|RuleBase:RU003553}; Flags: Fragment;+++[V9HW31_HUMAN|Unreviewed]RecName: Full=ATP synthase subunit beta {ECO:0000256|RuleBase:RU003553}; EC=3.6.3.14 {ECO:0000256|RuleBase:RU003553};"]
[5069,"'PAPPA'",1693,1193,972,1286,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0008270///zinc ion binding+++GO:0004222///metalloendopeptidase activity+++GO:0046872///metal ion binding+++GO:0004175///endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity","GO:0044267///cellular protein metabolic process+++GO:0006508///proteolysis+++GO:0007565///female pregnancy+++GO:0051384///response to glucocorticoid+++GO:0032354///response to follicle-stimulating hormone","pappalysin 1","[PAPP1_HUMAN|Reviewed]RecName: Full=Pappalysin-1; EC=3.4.24.79; AltName: Full=Insulin-like growth factor-dependent IGF-binding protein 4 protease; Short=IGF-dependent IGFBP-4 protease; Short=IGFBP-4ase; AltName: Full=Pregnancy-associated plasma protein A; Short=PAPP-A; Flags: Precursor;+++[A0A024R842_HUMAN|Unreviewed]SubName: Full=Pregnancy-associated plasma protein A, pappalysin 1, isoform CRA_b {ECO:0000313|EMBL:EAW87442.1};+++[B4DTA8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50208, highly similar to Pappalysin-1 {ECO:0000313|EMBL:BAG61920.1};+++[Q5QFB7_HUMAN|Unreviewed]SubName: Full=Pregnacy-associated plasma protein A {ECO:0000313|EMBL:AAV41521.1}; Flags: Fragment;+++[Q7Z613_HUMAN|Unreviewed]SubName: Full=Differentially placenta 1 expressed protein {ECO:0000313|EMBL:AAV41518.1}; SubName: Full=Replicative senescence upregulated protein {ECO:0000313|EMBL:AAP68818.1};+++[Q8IWT8_HUMAN|Unreviewed]SubName: Full=Aspecific BCL2 ARE-binding protein 2 {ECO:0000313|EMBL:AAN25598.1}; Flags: Fragment;"]
[50809,"'HP1BP3'",1523.63,1225.96,1297.22,1348.93666666667,{"$nulls":4},"GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0000786///nucleosome","GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding","GO:0071456///cellular response to hypoxia+++GO:0070828///heterochromatin organization+++GO:0042127///regulation of cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0097298///regulation of nucleus size+++GO:0006334///nucleosome assembly","heterochromatin protein 1 binding protein 3","[HP1B3_HUMAN|Reviewed]RecName: Full=Heterochromatin protein 1-binding protein 3; AltName: Full=Protein HP1-BP74 {ECO:0000303|PubMed:20042602};+++[B0QZK4_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000391721}; Flags: Fragment;+++[B0QZK5_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000397656}; Flags: Fragment;+++[B0QZK6_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000402096}; Flags: Fragment;+++[B0QZK7_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000401874}; Flags: Fragment;+++[B0QZK8_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000391281}; Flags: Fragment;+++[B0QZK9_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000405362}; Flags: Fragment;+++[B4E0N8_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1, binding protein 3, isoform CRA_b {ECO:0000313|EMBL:EAW94951.1}; SubName: Full=cDNA FLJ61197, highly similar to Homo sapiens heterochromatin protein 1, binding protein 3 (HP1BP3), mRNA {ECO:0000313|EMBL:BAG64500.1};+++[L8E9W8_HUMAN|Unreviewed]SubName: Full=Alternative protein HP1BP3 {ECO:0000313|EMBL:CCQ43536.1};+++[Q5SWC8_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000402754}; Flags: Fragment;+++[X6RGJ2_HUMAN|Unreviewed]SubName: Full=Heterochromatin protein 1-binding protein 3 {ECO:0000313|Ensembl:ENSP00000403039}; Flags: Fragment;"]
[5087,"'PBX1'",364,277,348,329.666666666667,"05202///Transcriptional misregulation in cancer+++04927///Cortisol synthesis and secretion+++04934///Cushing's syndrome","H00001///B lymphoblastic leukemia/lymphoma",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005667///transcription factor complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0048538///thymus development+++GO:0030154///cell differentiation+++GO:0006694///steroid biosynthetic process+++GO:0008284///positive regulation of cell proliferation+++GO:0030325///adrenal gland development+++GO:0035019///somatic stem cell population maintenance+++GO:0048706///embryonic skeletal system development+++GO:0042127///regulation of cell proliferation+++GO:0035162///embryonic hemopoiesis+++GO:0009952///anterior/posterior pattern specification+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0048536///spleen development+++GO:0007275///multicellular organism development+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0009887///animal organ morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048568///embryonic organ development+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0007548///sex differentiation+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0030326///embryonic limb morphogenesis+++GO:0030278///regulation of ossification+++GO:0045665///negative regulation of neuron differentiation+++GO:0001655///urogenital system development+++GO:0009954///proximal/distal pattern formation+++GO:0045944///positive regulation of transcription by RNA polymerase II","PBX homeobox 1","[PBX1_HUMAN|Reviewed]RecName: Full=Pre-B-cell leukemia transcription factor 1; AltName: Full=Homeobox protein PBX1; AltName: Full=Homeobox protein PRL;+++[A0A024R919_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1, isoform CRA_b {ECO:0000313|EMBL:EAW90740.1};+++[A0A087X0P4_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000483563};+++[A0A0A0MTI0_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000439943};+++[A8K5V0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76851, highly similar to Homo sapiens pre-B-cell leukemia transcription factor 1 (PBX1), mRNA {ECO:0000313|EMBL:BAF84104.1};+++[F8WA05_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000341455}; Flags: Fragment;+++[H0YKH1_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000452804}; Flags: Fragment;+++[H0YLB0_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW90738.1};+++[H0YLD4_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000453163}; Flags: Fragment;+++[H0YLF5_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000453188};+++[H0YLM3_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000453262}; Flags: Fragment;+++[H0YLT4_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000453331}; Flags: Fragment;+++[Q53YC7_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|EMBL:AAP35351.1}; SubName: Full=Pre-B-cell leukemia transcription factor 1, isoform CRA_c {ECO:0000313|EMBL:EAW90741.1};+++[S4R377_HUMAN|Unreviewed]SubName: Full=Pre-B-cell leukemia transcription factor 1 {ECO:0000313|Ensembl:ENSP00000473998};"]
[5095,"'PCCA'",93,96,77,88.6666666666667,"01120///Microbial metabolism in diverse environments+++00640///Propanoate metabolism+++00280///Valine, leucine and isoleucine degradation+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++01200///Carbon metabolism+++00630///Glyoxylate and dicarboxylate metabolism","H00175///Propionic acidemia+++H01400///Secondary hyperammonemia","M00741///Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA+++M00373///Ethylmalonyl pathway","R01859///propanoyl-CoA:carbon-dioxide ligase (ADP-forming)   ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005829///cytosol","GO:0004658///propionyl-CoA carboxylase activity+++GO:0005524///ATP binding+++GO:0019899///enzyme binding+++GO:0016874///ligase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0009374///biotin binding","GO:0006768///biotin metabolic process","propionyl-CoA carboxylase subunit alpha","[PCCA_HUMAN|Reviewed]RecName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial; Short=PCCase subunit alpha; EC=6.4.1.3; AltName: Full=Propanoyl-CoA:carbon dioxide ligase subunit alpha; Flags: Precursor;+++[A0A1B0GTR1_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000489804}; Flags: Fragment;+++[A0A1B0GU58_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000489974}; Flags: Fragment;+++[A0A1B0GUX9_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000490290}; Flags: Fragment;+++[A0A1B0GWA1_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000490843}; Flags: Fragment;+++[A0A1B0GWI4_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000490939}; Flags: Fragment;+++[A0A2R8Y725_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000495663};+++[H0Y4B9_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000390850}; Flags: Fragment;+++[H0Y5U0_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000400740}; Flags: Fragment;+++[H0Y798_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000411194}; Flags: Fragment;+++[Q5JTW6_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000396050}; Flags: Fragment;+++[Q5JVH2_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase alpha chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000399413}; Flags: Fragment;"]
[51010,"'EXOSC3'",93,98,87,92.6666666666667,"03018///RNA degradation","H00897///Pontocerebellar hypoplasia","M00391///Exosome, eukaryotes",null,"GO:0005829///cytosol+++GO:0035327///transcriptionally active chromatin+++GO:0000178///exosome (RNase complex)+++GO:0005737///cytoplasm+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0005654///nucleoplasm+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0004532///exoribonuclease activity","GO:0045830///positive regulation of isotype switching+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0045006///DNA deamination+++GO:0071034///CUT catabolic process+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0071049///nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription+++GO:0043488///regulation of mRNA stability+++GO:0006364///rRNA processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0045190///isotype switching+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0034475///U4 snRNA 3'-end processing+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing","exosome component 3","[EXOS3_HUMAN|Reviewed]RecName: Full=Exosome complex component RRP40; AltName: Full=Exosome component 3; AltName: Full=Ribosomal RNA-processing protein 40; AltName: Full=p10;+++[Q9NYS3_HUMAN|Unreviewed]SubName: Full=Apoptosis-related protein PNAS-3 {ECO:0000313|EMBL:AAF42918.1}; Flags: Fragment;"]
[51026,"'GOLT1B'",294,227,253,258,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport","golgi transport 1B","[GOT1B_HUMAN|Reviewed]RecName: Full=Vesicle transport protein GOT1B; AltName: Full=Germ cell tumor 2; AltName: Full=Golgi transport 1 homolog B; AltName: Full=Putative NF-kappa-B-activating protein 470; AltName: Full=hGOT1a;+++[F5GWD8_HUMAN|Unreviewed]SubName: Full=Vesicle transport protein GOT1B {ECO:0000313|Ensembl:ENSP00000441878};+++[F5GXH6_HUMAN|Unreviewed]SubName: Full=Vesicle transport protein GOT1B {ECO:0000313|Ensembl:ENSP00000446405};+++[F5H6U7_HUMAN|Unreviewed]SubName: Full=Vesicle transport protein GOT1B {ECO:0000313|Ensembl:ENSP00000437351};+++[G3V1U5_HUMAN|Unreviewed]SubName: Full=Golgi transport 1 homolog B (S. cerevisiae), isoform CRA_c {ECO:0000313|EMBL:EAW96441.1}; SubName: Full=Vesicle transport protein GOT1B {ECO:0000313|Ensembl:ENSP00000446231};"]
[51060,"'TXNDC12'",1091,942,1126,1053,"00480///Glutathione metabolism","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,"R02824///glutathione:insulin oxidoreductase   Insulin + 2 Glutathione <=> Reduced insulin + Glutathione disulfide+++R03915///glutathione:protein-disulfide oxidoreductase   Protein dithiol + Glutathione disulfide <=> Protein disulfide + 2 Glutathione","GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0019153///protein-disulfide reductase (glutathione) activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016491///oxidoreductase activity+++GO:0005515///protein binding","GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process+++GO:0060548///negative regulation of cell death","thioredoxin domain containing 12","[TXD12_HUMAN|Reviewed]RecName: Full=Thioredoxin domain-containing protein 12; EC=1.8.4.2; AltName: Full=Endoplasmic reticulum resident protein 18; Short=ER protein 18; Short=ERp18; AltName: Full=Endoplasmic reticulum resident protein 19; Short=ER protein 19; Short=ERp19; AltName: Full=Thioredoxin-like protein p19; AltName: Full=hTLP19; Flags: Precursor;+++[V9GY50_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000476401};+++[V9GYV4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000477120};"]
[51077,"'FCF1'",432,374,376,394,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome","GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis","FCF1, rRNA-processing protein","[FCF1_HUMAN|Reviewed]RecName: Full=rRNA-processing protein FCF1 homolog;+++[G3V1S4_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 111, isoform CRA_a {ECO:0000313|EMBL:EAW81187.1}; SubName: Full=rRNA-processing protein FCF1 homolog {ECO:0000313|Ensembl:ENSP00000444939};+++[G3V2M5_HUMAN|Unreviewed]SubName: Full=rRNA-processing protein FCF1 homolog {ECO:0000313|Ensembl:ENSP00000450750}; Flags: Fragment;+++[G3V3N8_HUMAN|Unreviewed]SubName: Full=rRNA-processing protein FCF1 homolog {ECO:0000313|Ensembl:ENSP00000451345};+++[G3V5D2_HUMAN|Unreviewed]SubName: Full=rRNA-processing protein FCF1 homolog {ECO:0000313|Ensembl:ENSP00000452297};+++[G3V5L8_HUMAN|Unreviewed]SubName: Full=rRNA-processing protein FCF1 homolog {ECO:0000313|Ensembl:ENSP00000452415};+++[G3V5S9_HUMAN|Unreviewed]SubName: Full=rRNA-processing protein FCF1 homolog {ECO:0000313|Ensembl:ENSP00000452497};+++[Q4FZ45_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 111, isoform CRA_c {ECO:0000313|EMBL:EAW81190.1}; SubName: Full=cDNA FLJ75920 {ECO:0000313|EMBL:BAF83355.1};+++[Q66K47_HUMAN|Unreviewed]SubName: Full=FCF1 protein {ECO:0000313|EMBL:AAH80600.1};"]
[51094,"'ADIPOR1'",2232,2237,2324,2264.33333333333,"04920///Adipocytokine signaling pathway+++04152///AMPK signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0046982///protein heterodimerization activity+++GO:0038023///signaling receptor activity+++GO:0019901///protein kinase binding+++GO:0097003///adipokinetic hormone receptor activity+++GO:0055100///adiponectin binding","GO:0006629///lipid metabolic process+++GO:0019216///regulation of lipid metabolic process+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0033210///leptin-mediated signaling pathway+++GO:0009755///hormone-mediated signaling pathway+++GO:0010633///negative regulation of epithelial cell migration+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0030308///negative regulation of cell growth+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0042304///regulation of fatty acid biosynthetic process+++GO:0042593///glucose homeostasis+++GO:0010906///regulation of glucose metabolic process+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0019395///fatty acid oxidation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0033211///adiponectin-activated signaling pathway+++GO:0006631///fatty acid metabolic process","adiponectin receptor 1","[PAQR1_HUMAN|Reviewed]RecName: Full=Adiponectin receptor protein 1 {ECO:0000303|PubMed:12802337}; AltName: Full=Progestin and adipoQ receptor family member 1 {ECO:0000303|PubMed:16044242}; AltName: Full=Progestin and adipoQ receptor family member I;+++[C9J0W7_HUMAN|Unreviewed]SubName: Full=Adiponectin receptor protein 1 {ECO:0000313|Ensembl:ENSP00000392946}; Flags: Fragment;+++[C9JNM5_HUMAN|Unreviewed]SubName: Full=Adiponectin receptor protein 1 {ECO:0000313|Ensembl:ENSP00000402178}; Flags: Fragment;+++[F8W782_HUMAN|Unreviewed]SubName: Full=Adiponectin receptor protein 1 {ECO:0000313|Ensembl:ENSP00000356223};"]
[51109,"'RDH11'",1905,1664,2387,1985.33333333333,"00830///Retinol metabolism+++01100///Metabolic pathways",null,null,"R08380///11-cis-retinol: NADP+ oxidoreductase   11-cis-Retinol + NADP+ <=> 11-cis-Retinal + NADPH + H++++R08379///retinol: NADP+ oxidoreductase   Retinol + NADP+ <=> Retinal + NADPH + H++++R08383///9-cis-Retinol + NADP+ <=> 9-cis-Retinal + NADPH + H+","GO:0001917///photoreceptor inner segment+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005622///intracellular+++GO:0016020///membrane","GO:0016491///oxidoreductase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0052650///NADP-retinol dehydrogenase activity+++GO:0005515///protein binding+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0042574///retinal metabolic process+++GO:0055114///oxidation-reduction process+++GO:0042572///retinol metabolic process+++GO:0016062///adaptation of rhodopsin mediated signaling+++GO:0001523///retinoid metabolic process","retinol dehydrogenase 11","[RDH11_HUMAN|Reviewed]RecName: Full=Retinol dehydrogenase 11; EC=1.1.1.300; AltName: Full=Androgen-regulated short-chain dehydrogenase/reductase 1; AltName: Full=HCV core-binding protein HCBP12; AltName: Full=Prostate short-chain dehydrogenase/reductase 1; AltName: Full=Retinal reductase 1; Short=RalR1; AltName: Full=Short chain dehydrogenase/reductase family 7C member 1;+++[A0A0S2Z575_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 isoform 2 {ECO:0000313|EMBL:ALQ34086.1};+++[A0A0S2Z583_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 isoform 1 {ECO:0000313|EMBL:ALQ34085.1}; Flags: Fragment;+++[B3KQ19_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 (All-trans and 9-cis), isoform CRA_a {ECO:0000313|EMBL:EAW80948.1}; SubName: Full=cDNA FLJ32633 fis, clone SYNOV2000171, highly similar to Retinol dehydrogenase 11 {ECO:0000313|EMBL:BAG51881.1};+++[G3V234_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000450435}; Flags: Fragment;+++[G3V2G6_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000450651}; Flags: Fragment;+++[G3V3K0_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000451280};+++[G3V510_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000452108};+++[H0YJ46_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 11 {ECO:0000313|Ensembl:ENSP00000450802}; Flags: Fragment;"]
[51128,"'SAR1B'",543.91,467.95,585.05,532.303333333333,"04141///Protein processing in endoplasmic reticulum+++05134///Legionellosis","H00927///Chylomicron retention disease (CRD)","M00404///COPII complex",null,"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005623///cell+++GO:0005783///endoplasmic reticulum+++GO:0070971///endoplasmic reticulum exit site+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0032580///Golgi cisterna membrane+++GO:0030127///COPII vesicle coat+++GO:0005794///Golgi apparatus","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0046872///metal ion binding","GO:0048208///COPII vesicle coating+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0015031///protein transport+++GO:0003400///regulation of COPII vesicle coating+++GO:0006886///intracellular protein transport+++GO:0061024///membrane organization+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016050///vesicle organization+++GO:0016192///vesicle-mediated transport","secretion associated Ras related GTPase 1B","[SAR1B_HUMAN|Reviewed]RecName: Full=GTP-binding protein SAR1b; AltName: Full=GTP-binding protein B; Short=GTBPB;+++[D6R9R5_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1b {ECO:0000313|Ensembl:ENSP00000423197}; Flags: Fragment;+++[D6RAA2_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1b {ECO:0000313|Ensembl:ENSP00000423005}; Flags: Fragment;+++[D6RD69_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1b {ECO:0000313|Ensembl:ENSP00000425466}; Flags: Fragment;+++[D6RDB2_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1b {ECO:0000313|Ensembl:ENSP00000425367};+++[Q9H029_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32259 fis, clone PROST1000298, highly similar to GTP-binding protein SAR1b {ECO:0000313|EMBL:BAG51815.1};"]
[51147,"'ING4'",502,562,525,529.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000123///histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0045111///intermediate filament cytoskeleton+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0035064///methylated histone binding+++GO:0003713///transcription coactivator activity","GO:0006473///protein acetylation+++GO:0008285///negative regulation of cell proliferation+++GO:0045926///negative regulation of growth+++GO:0043966///histone H3 acetylation+++GO:0007050///cell cycle arrest+++GO:0043065///positive regulation of apoptotic process+++GO:0007049///cell cycle+++GO:0043981///histone H4-K5 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0016573///histone acetylation+++GO:0006325///chromatin organization+++GO:0006915///apoptotic process+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043983///histone H4-K12 acetylation+++GO:0006260///DNA replication+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0043982///histone H4-K8 acetylation","inhibitor of growth family member 4","[ING4_HUMAN|Reviewed]RecName: Full=Inhibitor of growth protein 4; AltName: Full=p29ING4;+++[A4KYM5_HUMAN|Unreviewed]SubName: Full=Inhibitor of growth family member 4 variant deltaEx3 {ECO:0000313|EMBL:ABO61140.1}; SubName: Full=Inhibitor of growth protein 4 {ECO:0000313|Ensembl:ENSP00000433081};+++[A4KYM7_HUMAN|Unreviewed]SubName: Full=Inhibitor of growth family member 4 variant deltaEx6B {ECO:0000313|EMBL:ABO61142.1}; SubName: Full=cDNA FLJ53613, highly similar to Inhibitor of growth protein 4 {ECO:0000313|EMBL:BAG64415.1};+++[E9PJ14_HUMAN|Unreviewed]SubName: Full=Inhibitor of growth protein 4 {ECO:0000313|Ensembl:ENSP00000431892};+++[E9PNE3_HUMAN|Unreviewed]SubName: Full=Inhibitor of growth protein 4 {ECO:0000313|Ensembl:ENSP00000437198}; Flags: Fragment;+++[H0YEH7_HUMAN|Unreviewed]SubName: Full=Inhibitor of growth protein 4 {ECO:0000313|Ensembl:ENSP00000435867}; Flags: Fragment;+++[R4GNG1_HUMAN|Unreviewed]SubName: Full=Inhibitor of growth protein 4 {ECO:0000313|Ensembl:ENSP00000473635}; Flags: Fragment;"]
[51150,"'SDF4'",11496,13030,10944,11823.3333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0032059///bleb+++GO:0005770///late endosome+++GO:0005796///Golgi lumen+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0021549///cerebellum development+++GO:0070625///zymogen granule exocytosis+++GO:0045444///fat cell differentiation+++GO:0017156///calcium ion regulated exocytosis+++GO:0009650///UV protection+++GO:0045471///response to ethanol+++GO:0006887///exocytosis","stromal cell derived factor 4","[CAB45_HUMAN|Reviewed]RecName: Full=45 kDa calcium-binding protein; Short=Cab45; AltName: Full=Stromal cell-derived factor 4; Short=SDF-4; Flags: Precursor;+++[A0A024R084_HUMAN|Unreviewed]SubName: Full=Stromal cell derived factor 4, isoform CRA_c {ECO:0000313|EMBL:EAW56277.1};+++[A0A024R0A9_HUMAN|Unreviewed]SubName: Full=Stromal cell derived factor 4, isoform CRA_b {ECO:0000313|EMBL:EAW56276.1};+++[G3V1E2_HUMAN|Unreviewed]SubName: Full=45 kDa calcium-binding protein {ECO:0000313|Ensembl:ENSP00000435962}; SubName: Full=Stromal cell derived factor 4, isoform CRA_a {ECO:0000313|EMBL:EAW56271.1};+++[H0Y3T6_HUMAN|Unreviewed]SubName: Full=45 kDa calcium-binding protein {ECO:0000313|Ensembl:ENSP00000384207}; Flags: Fragment;"]
[51187,"'RSL24D1'",285,287,242,271.333333333333,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes+++M00179///Ribosome, archaea",null,"GO:0005783///endoplasmic reticulum+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0042788///polysomal ribosome+++GO:0045202///synapse+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding+++GO:0045296///cadherin binding","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0060041///retina development in camera-type eye+++GO:0042254///ribosome biogenesis+++GO:0007093///mitotic cell cycle checkpoint+++GO:0021554///optic nerve development+++GO:0000027///ribosomal large subunit assembly+++GO:0031290///retinal ganglion cell axon guidance+++GO:0010458///exit from mitosis+++GO:0006413///translational initiation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006412///translation+++GO:1902626///assembly of large subunit precursor of preribosome+++GO:0002181///cytoplasmic translation","ribosomal L24 domain containing 1","[RLP24_HUMAN|Reviewed]RecName: Full=Probable ribosome biogenesis protein RLP24; AltName: Full=Ribosomal L24 domain-containing protein 1; AltName: Full=Ribosomal protein L24-like;+++[A0A024R5U8_HUMAN|Unreviewed]SubName: Full=Chromosome 15 open reading frame 15, isoform CRA_a {ECO:0000313|EMBL:EAW77475.1};+++[C9JNW5_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L24 {ECO:0000313|Ensembl:ENSP00000420380}; SubName: Full=Ribosomal protein L24, isoform CRA_e {ECO:0000313|EMBL:EAW79784.1};+++[C9JXB8_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L24 {ECO:0000313|Ensembl:ENSP00000419179};+++[H3BMQ2_HUMAN|Unreviewed]SubName: Full=Probable ribosome biogenesis protein RLP24 {ECO:0000313|Ensembl:ENSP00000454492}; Flags: Fragment;+++[H3BPF2_HUMAN|Unreviewed]SubName: Full=Probable ribosome biogenesis protein RLP24 {ECO:0000313|Ensembl:ENSP00000455291};"]
[51193,"'ZNF639'",213,145,159,172.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0043621///protein self-association+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0030307///positive regulation of cell growth+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II","zinc finger protein 639","[ZN639_HUMAN|Reviewed]RecName: Full=Zinc finger protein 639; AltName: Full=Zinc finger protein ANC_2H01; AltName: Full=Zinc finger protein ZASC1;+++[C9IZP0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 639 {ECO:0000313|Ensembl:ENSP00000418628}; Flags: Fragment;+++[C9J3R1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 639 {ECO:0000313|Ensembl:ENSP00000417232}; Flags: Fragment;+++[J3KR59_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 639 {ECO:0000313|Ensembl:ENSP00000418870}; Flags: Fragment;+++[J3KR68_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 639 {ECO:0000313|Ensembl:ENSP00000419650}; Flags: Fragment;"]
[51234,"'EMC4'",744,766,697,735.666666666667,null,"H00606///Early infantile epileptic encephalopathy+++H00816///Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)+++H01815///Malignant migrating partial seizures in infancy",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0072546///ER membrane protein complex","GO:0015079///potassium ion transmembrane transporter activity+++GO:0019901///protein kinase binding+++GO:0015379///potassium:chloride symporter activity","GO:0034975///protein folding in endoplasmic reticulum+++GO:0006915///apoptotic process","ER membrane protein complex subunit 4","[EMC4_HUMAN|Reviewed]RecName: Full=ER membrane protein complex subunit 4; AltName: Full=Cell proliferation-inducing gene 17 protein; AltName: Full=Transmembrane protein 85;+++[A0A024R9N3_HUMAN|Unreviewed]RecName: Full=ER membrane protein complex subunit 4 {ECO:0000256|PIRNR:PIRNR017207};+++[A0A0S2Z598_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 85 isoform 1 {ECO:0000313|EMBL:ALQ34098.1}; Flags: Fragment;+++[H0YK61_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452672};+++[H0YKL2_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452849}; Flags: Fragment;+++[H0YLP8_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000453287}; Flags: Fragment;+++[H0YMH5_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000453610};+++[H0YN63_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000453880};+++[H0YNK0_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000454042};+++[H0YNK8_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000454052};+++[S4R329_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 4 {ECO:0000313|Ensembl:ENSP00000473881};"]
[51247,"'PAIP2'",774,876,768,806,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0030371///translation repressor activity+++GO:0005515///protein binding+++GO:0003729///mRNA binding","GO:0006417///regulation of translation+++GO:0007613///memory+++GO:1900271///regulation of long-term synaptic potentiation+++GO:0045947///negative regulation of translational initiation+++GO:0017148///negative regulation of translation+++GO:0007283///spermatogenesis","poly(A) binding protein interacting protein 2","[PAIP2_HUMAN|Reviewed]RecName: Full=Polyadenylate-binding protein-interacting protein 2; Short=PABP-interacting protein 2; Short=PAIP-2; Short=Poly(A)-binding protein-interacting protein 2;+++[D6R9Y1_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000422821};+++[D6RA77_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000423084}; Flags: Fragment;+++[Q49AE6_HUMAN|Unreviewed]SubName: Full=PAIP2 protein {ECO:0000313|EMBL:AAH39337.1};+++[Q6FID7_HUMAN|Unreviewed]SubName: Full=PAIP2 protein {ECO:0000313|EMBL:CAG38520.1};"]
[51258,"'MRPL51'",439,497,363,433,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0005840///ribosome+++GO:0005761///mitochondrial ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination","mitochondrial ribosomal protein L51","[RM51_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L51, mitochondrial; Short=L51mt; Short=MRP-L51; AltName: Full=Mitochondrial large ribosomal subunit protein mL51 {ECO:0000303|PubMed:25278503}; AltName: Full=bMRP-64; Short=bMRP64; Flags: Precursor;+++[A0A087WU28_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L51, mitochondrial {ECO:0000313|Ensembl:ENSP00000478326}; Flags: Fragment;+++[A0A0B4J2C1_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L51, mitochondrial {ECO:0000313|Ensembl:ENSP00000477598};+++[M0R176_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L51, mitochondrial {ECO:0000313|Ensembl:ENSP00000471687};"]
[51285,"'RASL12'",55,58,152,88.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding","GO:0007165///signal transduction","RAS like family 12","[RASLC_HUMAN|Reviewed]RecName: Full=Ras-like protein family member 12; AltName: Full=Ras-like protein Ris;+++[A0A024R5Y3_HUMAN|Unreviewed]SubName: Full=RAS-like, family 12, isoform CRA_a {ECO:0000313|EMBL:EAW77710.1};"]
[51295,"'ECSIT'",346,413,439,399.333333333333,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016651///oxidoreductase activity, acting on NAD(P)H+++GO:0005515///protein binding","GO:0051341///regulation of oxidoreductase activity+++GO:0055114///oxidation-reduction process+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0045087///innate immune response+++GO:0002376///immune system process","ECSIT signalling integrator","[ECSIT_HUMAN|Reviewed]RecName: Full=Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; AltName: Full=Protein SITPEC; Flags: Precursor;+++[J3KTF5_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000462957}; Flags: Fragment;+++[K7EIK2_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000464783}; Flags: Fragment;+++[K7EJG5_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000465162}; Flags: Fragment;+++[K7EJI1_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000465181}; Flags: Fragment;+++[K7EM98_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000466415}; Flags: Fragment;+++[K7EN32_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000466762};+++[K7EPL5_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000467436}; Flags: Fragment;+++[K7ESM8_HUMAN|Unreviewed]SubName: Full=Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial {ECO:0000313|Ensembl:ENSP00000468783};"]
[51320,"'MEX3C'",820,622,660,700.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0045598///regulation of fat cell differentiation+++GO:0003415///chondrocyte hypertrophy+++GO:0097009///energy homeostasis","mex-3 RNA binding family member C","[MEX3C_HUMAN|Reviewed]RecName: Full=RNA-binding E3 ubiquitin-protein ligase MEX3C; EC=2.3.2.27; AltName: Full=RING finger and KH domain-containing protein 2; AltName: Full=RING finger protein 194; AltName: Full=RING-type E3 ubiquitin transferase MEX3C {ECO:0000305};+++[K7ER23_HUMAN|Unreviewed]SubName: Full=RNA-binding E3 ubiquitin-protein ligase MEX3C {ECO:0000313|Ensembl:ENSP00000468078}; Flags: Fragment;+++[M9T4I7_HUMAN|Unreviewed]SubName: Full=MEX3C variant 2 {ECO:0000313|EMBL:AGI99529.1}; SubName: Full=RNA-binding E3 ubiquitin-protein ligase MEX3C {ECO:0000313|Ensembl:ENSP00000482566};"]
[51332,"'SPTBN5'",46,43,56,48.3333333333333,null,"H00230///Hereditary spherocytosis (SPH)+++H01891///Autosomal recessive spinocerebellar ataxias+++H00231///Hereditary elliptocytosis (HE)+++H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0016020///membrane+++GO:0097381///photoreceptor disc membrane+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0008091///spectrin+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0032391///photoreceptor connecting cilium+++GO:0031941///filamentous actin","GO:0045505///dynein intermediate chain binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0034452///dynactin binding+++GO:0043621///protein self-association+++GO:0032029///myosin tail binding+++GO:0019894///kinesin binding+++GO:0030507///spectrin binding+++GO:0003779///actin binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007041///lysosomal transport+++GO:0030036///actin cytoskeleton organization+++GO:0000165///MAPK cascade+++GO:0007411///axon guidance+++GO:0007030///Golgi organization+++GO:0051260///protein homooligomerization+++GO:0051693///actin filament capping","spectrin beta, non-erythrocytic 5","[SPTN5_HUMAN|Reviewed]RecName: Full=Spectrin beta chain, non-erythrocytic 5; AltName: Full=Beta-V spectrin;"]
[51372,"'TMA7'",1029,1176,1033,1079.33333333333,{"$nulls":6},"GO:0002181///cytoplasmic translation","translation machinery associated 7 homolog","[TMA7_HUMAN|Reviewed]RecName: Full=Translation machinery-associated protein 7; AltName: Full=Coiled-coil domain-containing protein 72;+++[A0A024R306_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 72, isoform CRA_a {ECO:0000313|EMBL:EAW64874.1};"]
[5138,"'PDE2A'",43,58,153,84.6666666666667,"05032///Morphine addiction+++00230///Purine metabolism+++04740///Olfactory transduction+++04925///Aldosterone synthesis and secretion+++04022///cGMP-PKG signaling pathway",null,"M00694///cGMP signaling","R01234///Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase   3',5'-Cyclic GMP + H2O <=> GMP+++R00191///adenosine 3',5'-phosphate 5'-nucleotidohydrolase   3',5'-Cyclic AMP + H2O <=> AMP","GO:0042734///presynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0042301///phosphate ion binding+++GO:0042802///identical protein binding+++GO:0000166///nucleotide binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0030552///cAMP binding+++GO:0005262///calcium channel activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0004118///cGMP-stimulated cyclic-nucleotide phosphodiesterase activity+++GO:0030553///cGMP binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity+++GO:0000287///magnesium ion binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0008144///drug binding+++GO:0005515///protein binding+++GO:0030911///TPR domain binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043117///positive regulation of vascular permeability+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1904613///cellular response to 2,3,7,8-tetrachlorodibenzodioxine+++GO:0033159///negative regulation of protein import into nucleus, translocation+++GO:0019933///cAMP-mediated signaling+++GO:0071260///cellular response to mechanical stimulus+++GO:0007165///signal transduction+++GO:0043116///negative regulation of vascular permeability+++GO:0019934///cGMP-mediated signaling+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0010821///regulation of mitochondrion organization+++GO:0046069///cGMP catabolic process+++GO:0071321///cellular response to cGMP+++GO:0070588///calcium ion transmembrane transport+++GO:0061028///establishment of endothelial barrier+++GO:0010754///negative regulation of cGMP-mediated signaling+++GO:0030224///monocyte differentiation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0050729///positive regulation of inflammatory response+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0010628///positive regulation of gene expression+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0035690///cellular response to drug+++GO:0071320///cellular response to cAMP","phosphodiesterase 2A","[PDE2A_HUMAN|Reviewed]RecName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase; EC=3.1.4.17; AltName: Full=Cyclic GMP-stimulated phosphodiesterase; Short=CGS-PDE; Short=cGSPDE;+++[C9JPD5_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000388997}; Flags: Fragment;+++[E9PEF1_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[F5GXX2_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000440834}; Flags: Fragment;+++[F5H130_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000439683}; Flags: Fragment;+++[F5H143_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000438008};+++[F5H1D7_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000445750}; Flags: Fragment;+++[F5H2R8_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000445443};+++[F5H2V7_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000439302};+++[F5H2Z0_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000438295};+++[F5H3Z7_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000438559};+++[F5H5P8_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000443232}; Flags: Fragment;+++[H0YFL1_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000439077}; Flags: Fragment;+++[H0YG13_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000441322}; Flags: Fragment;+++[H0YGL2_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000443737}; Flags: Fragment;+++[H7C009_HUMAN|Unreviewed]SubName: Full=cGMP-dependent 3',5'-cyclic phosphodiesterase {ECO:0000313|Ensembl:ENSP00000392457}; Flags: Fragment;+++[L8E8Y0_HUMAN|Unreviewed]SubName: Full=Alternative protein PDE2A {ECO:0000313|EMBL:CCQ43186.1};+++[Q8IW54_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};"]
[5143,"'PDE4C'",13.26,6.91,13.01,11.06,"00230///Purine metabolism+++04024///cAMP signaling pathway+++05032///Morphine addiction+++04928///Parathyroid hormone synthesis, secretion and action",null,null,"R00191///adenosine 3',5'-phosphate 5'-nucleotidohydrolase   3',5'-Cyclic AMP + H2O <=> AMP","GO:0042995///cell projection+++GO:0005575///cellular_component+++GO:0005829///cytosol+++GO:0005929///cilium+++GO:0005615///extracellular space","GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004112///cyclic-nucleotide phosphodiesterase activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006198///cAMP catabolic process+++GO:0007165///signal transduction+++GO:0008150///biological_process","phosphodiesterase 4C","[PDE4C_HUMAN|Reviewed]RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C; EC=3.1.4.53; AltName: Full=DPDE1; AltName: Full=PDE21;+++[A0A2R9YJK9_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C {ECO:0000313|Ensembl:ENSP00000474591}; Flags: Fragment;+++[B7Z6T1_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C {ECO:0000313|Ensembl:ENSP00000473713}; SubName: Full=cDNA FLJ50236, highly similar to cAMP-specific 3',5'-cyclic phosphodiesterase 4C {ECO:0000313|EMBL:BAH13367.1};+++[M0R1P5_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C {ECO:0000313|Ensembl:ENSP00000472034}; Flags: Fragment;+++[O43849_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[O43850_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[O43851_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[O76104_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[O76105_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[P78505_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[Q2VPB9_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[Q32MM7_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[Q7KYS4_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[Q9P1U3_HUMAN|Unreviewed]SubName: Full=PDE4C [amino acids 597-712] {ECO:0000313|EMBL:AAF67386.1}; Flags: Fragment;+++[Q9UPJ5_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[U3KPR3_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C {ECO:0000313|Ensembl:ENSP00000473937}; Flags: Fragment;+++[U3KPR4_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C {ECO:0000313|Ensembl:ENSP00000474849}; Flags: Fragment;+++[V9GYP2_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4C {ECO:0000313|Ensembl:ENSP00000476961}; Flags: Fragment;"]
[5144,"'PDE4D'",86,72,71,76.3333333333333,"04928///Parathyroid hormone synthesis, secretion and action+++05032///Morphine addiction+++00230///Purine metabolism+++04024///cAMP signaling pathway",null,null,"R00191///adenosine 3',5'-phosphate 5'-nucleotidohydrolase   3',5'-Cyclic AMP + H2O <=> AMP","GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0034704///calcium channel complex+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0016324///apical plasma membrane+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005891///voltage-gated calcium channel complex","GO:0097110///scaffold protein binding+++GO:0030552///cAMP binding+++GO:0044325///ion channel binding+++GO:0008144///drug binding+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0019899///enzyme binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0051117///ATPase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0031698///beta-2 adrenergic receptor binding+++GO:0016787///hydrolase activity","GO:0032729///positive regulation of interferon-gamma production+++GO:0002027///regulation of heart rate+++GO:0086024///adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate+++GO:0032754///positive regulation of interleukin-5 production+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006939///smooth muscle contraction+++GO:0007568///aging+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:0007165///signal transduction+++GO:0050852///T cell receptor signaling pathway+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0010469///regulation of signaling receptor activity+++GO:0071320///cellular response to cAMP+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0045822///negative regulation of heart contraction+++GO:0019933///cAMP-mediated signaling+++GO:0032743///positive regulation of interleukin-2 production+++GO:0006198///cAMP catabolic process+++GO:0061028///establishment of endothelial barrier+++GO:0071875///adrenergic receptor signaling pathway+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:1901898///negative regulation of relaxation of cardiac muscle+++GO:0030593///neutrophil chemotaxis+++GO:0071872///cellular response to epinephrine stimulus+++GO:0035264///multicellular organism growth+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0050900///leukocyte migration","phosphodiesterase 4D","[PDE4D_HUMAN|Reviewed]RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D; EC=3.1.4.53; AltName: Full=DPDE3; AltName: Full=PDE43;+++[A0A087WSZ7_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[A0A140VJR0_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[A0A1B0GW84_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[A0A1W2PQN6_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D {ECO:0000313|Ensembl:ENSP00000492052};+++[D6R9L4_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D {ECO:0000313|Ensembl:ENSP00000423555};+++[D6RAQ0_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D {ECO:0000313|Ensembl:ENSP00000421829}; Flags: Fragment;+++[D6RBB2_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D {ECO:0000313|Ensembl:ENSP00000424281};+++[D6RHE0_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[D6RIG1_HUMAN|Unreviewed]SubName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D {ECO:0000313|Ensembl:ENSP00000425910}; Flags: Fragment;+++[O43862_HUMAN|Unreviewed]SubName: Full=3'5' cyclic nucleotide phosphodiesterase 4D splice variant 1 {ECO:0000313|EMBL:AAC51928.1}; Flags: Fragment;+++[Q9HCX6_HUMAN|Unreviewed]SubName: Full=cAMP-specific phosphodiesterase 4D {ECO:0000313|EMBL:CAC03758.1};"]
[51496,"'CTDSPL2'",232,159,176,189,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0016791///phosphatase activity+++GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity","GO:0030514///negative regulation of BMP signaling pathway+++GO:0006470///protein dephosphorylation+++GO:0046827///positive regulation of protein export from nucleus","CTD small phosphatase like 2","[CTSL2_HUMAN|Reviewed]RecName: Full=CTD small phosphatase-like protein 2; Short=CTDSP-like 2; EC=3.1.3.-;+++[A0A024R5Q8_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2, isoform CRA_a {ECO:0000313|EMBL:EAW77266.1};+++[H0YMB4_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein 2 {ECO:0000313|Ensembl:ENSP00000453538}; Flags: Fragment;+++[H0YMH7_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein 2 {ECO:0000313|Ensembl:ENSP00000453612}; Flags: Fragment;+++[H0YNU2_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein 2 {ECO:0000313|Ensembl:ENSP00000454154}; Flags: Fragment;+++[H0YNW9_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein 2 {ECO:0000313|Ensembl:ENSP00000454187}; Flags: Fragment;+++[L8E9X2_HUMAN|Unreviewed]SubName: Full=Alternative protein CTDSPL2 {ECO:0000313|EMBL:CCQ43541.1};"]
[51501,"'HIKESHI'",187,199,164,183.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0008565///protein transporter activity+++GO:0030544///Hsp70 protein binding","GO:0015031///protein transport+++GO:0006606///protein import into nucleus+++GO:0030324///lung development+++GO:0007030///Golgi organization+++GO:0034605///cellular response to heat+++GO:1900034///regulation of cellular response to heat","Hikeshi, heat shock protein nuclear import factor","[HIKES_HUMAN|Reviewed]RecName: Full=Protein Hikeshi {ECO:0000305};+++[A0A087WYW7_HUMAN|Unreviewed]SubName: Full=Protein Hikeshi {ECO:0000313|Ensembl:ENSP00000482151};+++[E9PJB2_HUMAN|Unreviewed]SubName: Full=Protein Hikeshi {ECO:0000313|Ensembl:ENSP00000433815};+++[E9PPG8_HUMAN|Unreviewed]SubName: Full=Protein Hikeshi {ECO:0000313|Ensembl:ENSP00000432699};"]
[51524,"'TMEM138'",330,400,414,381.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0005773///vacuole+++GO:0005774///vacuolar membrane+++GO:0016020///membrane+++GO:0005929///cilium+++GO:0016021///integral component of membrane","GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding","GO:0060271///cilium assembly+++GO:0030030///cell projection organization","transmembrane protein 138","[TM138_HUMAN|Reviewed]RecName: Full=Transmembrane protein 138;+++[J3QSZ6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 138 {ECO:0000313|Ensembl:ENSP00000371206};"]
[5154,"'PDGFA'",315,293,345,317.666666666667,"05418///Fluid shear stress and atherosclerosis+++01521///EGFR tyrosine kinase inhibitor resistance+++04014///Ras signaling pathway+++04630///Jak-STAT signaling pathway+++05215///Prostate cancer+++04540///Gap junction+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++05166///HTLV-I infection+++05218///Melanoma+++04072///Phospholipase D signaling pathway+++05206///MicroRNAs in cancer+++04015///Rap1 signaling pathway+++05231///Choline metabolism in cancer+++05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++05202///Transcriptional misregulation in cancer+++04010///MAPK signaling pathway+++05214///Glioma","H00015///Malignant pleural mesothelioma+++H00042///Glioma",null,null,"GO:0009986///cell surface+++GO:0005615///extracellular space+++GO:0031093///platelet alpha granule lumen+++GO:0005576///extracellular region+++GO:0005902///microvillus+++GO:0005796///Golgi lumen+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005788///endoplasmic reticulum lumen","GO:0005161///platelet-derived growth factor receptor binding+++GO:0005515///protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0008083///growth factor activity+++GO:0005518///collagen binding+++GO:0042802///identical protein binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0048407///platelet-derived growth factor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity","GO:0051897///positive regulation of protein kinase B signaling+++GO:2000278///regulation of DNA biosynthetic process+++GO:0030031///cell projection assembly+++GO:0002576///platelet degranulation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0010512///negative regulation of phosphatidylinositol biosynthetic process+++GO:0030335///positive regulation of cell migration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0060683///regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling+++GO:0042060///wound healing+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0072124///regulation of glomerular mesangial cell proliferation+++GO:0030198///extracellular matrix organization+++GO:0001942///hair follicle development+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048286///lung alveolus development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0051781///positive regulation of cell division+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0043588///skin development+++GO:0010469///regulation of signaling receptor activity+++GO:0014910///regulation of smooth muscle cell migration+++GO:0009887///animal organ morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0007275///multicellular organism development+++GO:0035793///positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway+++GO:1990401///embryonic lung development+++GO:0008284///positive regulation of cell proliferation+++GO:0001525///angiogenesis+++GO:0050919///negative chemotaxis+++GO:0009611///response to wounding+++GO:0007267///cell-cell signaling+++GO:0001775///cell activation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0010544///negative regulation of platelet activation+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0000165///MAPK cascade","platelet derived growth factor subunit A","[PDGFA_HUMAN|Reviewed]RecName: Full=Platelet-derived growth factor subunit A; Short=PDGF subunit A; AltName: Full=PDGF-1; AltName: Full=Platelet-derived growth factor A chain; AltName: Full=Platelet-derived growth factor alpha polypeptide; Flags: Precursor;+++[A0A024R7Z9_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor alpha polypeptide, isoform CRA_a {ECO:0000313|EMBL:EAW87162.1};+++[A0A0A0MSC4_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor subunit A {ECO:0000313|Ensembl:ENSP00000384673}; Flags: Fragment;+++[H7BYW6_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor subunit A {ECO:0000313|Ensembl:ENSP00000383572}; Flags: Fragment;+++[Q32M96_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor alpha polypeptide {ECO:0000313|EMBL:AAI09247.1};+++[Q9UGN0_HUMAN|Unreviewed]SubName: Full=Platelet-derived growth factor A chain {ECO:0000313|EMBL:CAB59509.1}; Flags: Fragment;"]
[51567,"'TDP2'",271,204,196,223.666666666667,null,"H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0016235///aggresome+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0004518///nuclease activity+++GO:0036317///tyrosyl-RNA phosphodiesterase activity+++GO:0003697///single-stranded DNA binding+++GO:0070260///5'-tyrosyl-DNA phosphodiesterase activity+++GO:0030145///manganese ion binding+++GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0003714///transcription corepressor activity","GO:0006281///DNA repair+++GO:0048666///neuron development+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007166///cell surface receptor signaling pathway+++GO:0006302///double-strand break repair+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0006974///cellular response to DNA damage stimulus","tyrosyl-DNA phosphodiesterase 2","[TYDP2_HUMAN|Reviewed]RecName: Full=Tyrosyl-DNA phosphodiesterase 2; Short=Tyr-DNA phosphodiesterase 2; Short=hTDP2; EC=3.1.4.-; AltName: Full=5'-tyrosyl-DNA phosphodiesterase; Short=5'-Tyr-DNA phosphodiesterase; AltName: Full=ETS1-associated protein 2; AltName: Full=ETS1-associated protein II; Short=EAPII; AltName: Full=TRAF and TNF receptor-associated protein; AltName: Full=Tyrosyl-RNA phosphodiesterase; AltName: Full=VPg unlinkase;+++[I3QNV0_HUMAN|Unreviewed]SubName: Full=Tyrosyl-DNA phosphodiesterase 2 {ECO:0000313|EMBL:AFK13123.1}; Flags: Fragment;+++[X6R5A3_HUMAN|Unreviewed]SubName: Full=TRAF and TNF receptor associated protein, isoform CRA_b {ECO:0000313|EMBL:EAW55459.1}; SubName: Full=Tyrosyl-DNA phosphodiesterase 2 {ECO:0000313|Ensembl:ENSP00000345345};"]
[51593,"'SRRT'",1686,1773,1551,1670,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:0031053///primary miRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0097150///neuronal stem cell population maintenance+++GO:0031047///gene silencing by RNA+++GO:0050769///positive regulation of neurogenesis+++GO:0046685///response to arsenic-containing substance+++GO:0006397///mRNA processing+++GO:0006355///regulation of transcription, DNA-templated","serrate, RNA effector molecule","[SRRT_HUMAN|Reviewed]RecName: Full=Serrate RNA effector molecule homolog; AltName: Full=Arsenite-resistance protein 2;+++[A0A087X0F4_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000483348};+++[A0A0A0MSP6_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000398618}; Flags: Fragment;+++[A0A286YEP7_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000492916}; Flags: Fragment;+++[C9JUL9_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000400912}; Flags: Fragment;+++[H7C0U8_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000396807}; Flags: Fragment;+++[H7C1K0_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000400703}; Flags: Fragment;+++[H7C3A1_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000410588}; Flags: Fragment;"]
[5162,"'PDHB'",895,904,785,861.333333333333,"01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01200///Carbon metabolism+++04066///HIF-1 signaling pathway+++00020///Citrate cycle (TCA cycle)+++01120///Microbial metabolism in diverse environments+++00620///Pyruvate metabolism+++04922///Glucagon signaling pathway+++00010///Glycolysis / Gluconeogenesis+++01110///Biosynthesis of secondary metabolites+++05230///Central carbon metabolism in cancer","H00072///Pyruvate dehydrogenase complex deficiency+++H01998///Pyruvate dehydrogenase E1-beta deficiency","M00307///Pyruvate oxidation, pyruvate => acetyl-CoA","R00209///pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate   Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H++++R00014///pyruvate:thiamin diphosphate acetaldehydetransferase (decarboxylating)   Pyruvate + Thiamin diphosphate <=> 2-(alpha-Hydroxyethyl)thiamine diphosphate + CO2+++R03270///2-(alpha-Hydroxyethyl)thiamine diphosphate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + Thiamin diphosphate+++R01699///pyruvate:[dihydrolipoyllysine-residue acetyltransferase]-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-acetylating)   Pyruvate + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2","GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0045254///pyruvate dehydrogenase complex+++GO:0005654///nucleoplasm+++GO:0005759///mitochondrial matrix","GO:0005515///protein binding+++GO:0034604///pyruvate dehydrogenase (NAD+) activity+++GO:0003824///catalytic activity+++GO:0004739///pyruvate dehydrogenase (acetyl-transferring) activity+++GO:0004738///pyruvate dehydrogenase activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0006086///acetyl-CoA biosynthetic process from pyruvate+++GO:0006099///tricarboxylic acid cycle+++GO:0006006///glucose metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate","pyruvate dehydrogenase E1 beta subunit","[ODPB_HUMAN|Reviewed]RecName: Full=Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; Short=PDHE1-B; EC=1.2.4.1; Flags: Precursor;+++[C9J634_HUMAN|Unreviewed]SubName: Full=Pyruvate dehydrogenase E1 component subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000418448};+++[F8WF02_HUMAN|Unreviewed]SubName: Full=Pyruvate dehydrogenase E1 component subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000419580};"]
[51645,"'PPIL1'",448,353,385,395.333333333333,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071007///U2-type catalytic step 2 spliceosome","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding+++GO:0016853///isomerase activity+++GO:0016018///cyclosporin A binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006457///protein folding+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0000413///protein peptidyl-prolyl isomerization","peptidylprolyl isomerase like 1","[PPIL1_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 1; Short=PPIase; EC=5.2.1.8 {ECO:0000269|PubMed:16595688}; AltName: Full=Rotamase PPIL1;+++[A0A024RCX8_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[51665,"'ASB1'",482,341,399,407.333333333333,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0005829///cytosol","GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding","GO:0035556///intracellular signal transduction+++GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination+++GO:0030539///male genitalia development+++GO:0042036///negative regulation of cytokine biosynthetic process+++GO:0007275///multicellular organism development","ankyrin repeat and SOCS box containing 1","[ASB1_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 1; Short=ASB-1;+++[B9A047_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 1 {ECO:0000313|Ensembl:ENSP00000387025};+++[F8WBM8_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 1 {ECO:0000313|Ensembl:ENSP00000411773};"]
[51699,"'VPS29'",338,328,320,328.666666666667,"04144///Endocytosis",{"$nulls":3},"GO:0010008///endosome membrane+++GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030906///retromer, cargo-selective complex+++GO:0005770///late endosome+++GO:0030904///retromer complex+++GO:0016020///membrane+++GO:0005768///endosome","GO:0008565///protein transporter activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0015031///protein transport+++GO:0010506///regulation of autophagy+++GO:0016032///viral process+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0016055///Wnt signaling pathway+++GO:0006886///intracellular protein transport+++GO:0042147///retrograde transport, endosome to Golgi","VPS29, retromer complex component","[VPS29_HUMAN|Reviewed]RecName: Full=Vacuolar protein sorting-associated protein 29; Short=hVPS29; AltName: Full=PEP11 homolog; AltName: Full=Vesicle protein sorting 29;+++[F8VXU5_HUMAN|Unreviewed]RecName: Full=Vacuolar protein sorting-associated protein 29 {ECO:0000256|RuleBase:RU362040}; AltName: Full=Vesicle protein sorting 29 {ECO:0000256|RuleBase:RU362040};+++[Q05DG7_HUMAN|Unreviewed]SubName: Full=VPS29 protein {ECO:0000313|EMBL:AAH15095.1}; SubName: Full=Vacuolar protein sorting-associated protein 29 {ECO:0000313|Ensembl:ENSP00000400048};+++[Q8N0S8_HUMAN|Unreviewed]SubName: Full=VPS29 protein {ECO:0000313|EMBL:AAH32462.1};"]
[51725,"'FBXO40'",1,2,2,1.66666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0000209///protein polyubiquitination+++GO:0043687///post-translational protein modification+++GO:0042692///muscle cell differentiation","F-box protein 40","[FBX40_HUMAN|Reviewed]RecName: Full=F-box only protein 40; AltName: Full=Muscle disease-related protein;+++[L8ECG7_HUMAN|Unreviewed]SubName: Full=Alternative protein FBXO40 {ECO:0000313|EMBL:CCQ43537.1};"]
[51755,"'CDK12'",986,634,746,788.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005694///chromosome+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000790///nuclear chromatin+++GO:0001650///fibrillar center+++GO:0019908///nuclear cyclin-dependent protein kinase holoenzyme complex+++GO:0002944///cyclin K-CDK12 complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008024///cyclin/CDK positive transcription elongation factor complex","GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0008134///transcription factor binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0004672///protein kinase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0019901///protein kinase binding","GO:0008380///RNA splicing+++GO:0006468///protein phosphorylation+++GO:0051726///regulation of cell cycle+++GO:0043405///regulation of MAP kinase activity+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:2000737///negative regulation of stem cell differentiation+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0016310///phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II","cyclin dependent kinase 12","[CDK12_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 12; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cdc2-related kinase, arginine/serine-rich; Short=CrkRS; AltName: Full=Cell division cycle 2-related protein kinase 7; Short=CDC2-related protein kinase 7; AltName: Full=Cell division protein kinase 12; Short=hCDK12;+++[A0A2I6PNI6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 12 {ECO:0000313|EMBL:AUM62215.1}; Flags: Fragment;+++[H0YLT2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 12 {ECO:0000313|Ensembl:ENSP00000453329}; Flags: Fragment;+++[J3QSD7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 12 {ECO:0000313|Ensembl:ENSP00000464641}; Flags: Fragment;"]
[51780,"'KDM3B'",1155,867,971,997.666666666667,"04714///Thermogenesis",{"$nulls":3},"GO:0005634///nucleus+++GO:0000785///chromatin+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0016209///antioxidant activity+++GO:0051213///dioxygenase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0031490///chromatin DNA binding","GO:0055114///oxidation-reduction process+++GO:0098869///cellular oxidant detoxification+++GO:0033169///histone H3-K9 demethylation+++GO:0006325///chromatin organization+++GO:0072718///response to cisplatin","lysine demethylase 3B","[KDM3B_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 3B; EC=1.14.11.-; AltName: Full=JmjC domain-containing histone demethylation protein 2B; AltName: Full=Jumonji domain-containing protein 1B; AltName: Full=Nuclear protein 5qNCA;+++[A4FUT8_HUMAN|Unreviewed]SubName: Full=JMJD1B protein {ECO:0000313|EMBL:AAI17694.1}; Flags: Fragment;+++[H0Y946_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 3B {ECO:0000313|Ensembl:ENSP00000423012}; Flags: Fragment;+++[H0Y9V5_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 3B {ECO:0000313|Ensembl:ENSP00000425186}; Flags: Fragment;"]
[5196,"'PF4'",0.83,0,1,0.61,"04060///Cytokine-cytokine receptor interaction+++04062///Chemokine signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031093///platelet alpha granule lumen+++GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0008009///chemokine activity+++GO:0048248///CXCR3 chemokine receptor binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0008201///heparin binding","GO:0045653///negative regulation of megakaryocyte differentiation+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0016525///negative regulation of angiogenesis+++GO:0030595///leukocyte chemotaxis+++GO:0071222///cellular response to lipopolysaccharide+++GO:0019221///cytokine-mediated signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:0045651///positive regulation of macrophage differentiation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0045347///negative regulation of MHC class II biosynthetic process+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0010469///regulation of signaling receptor activity+++GO:0070098///chemokine-mediated signaling pathway+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0030168///platelet activation+++GO:0002576///platelet degranulation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006935///chemotaxis+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0045918///negative regulation of cytolysis+++GO:0030593///neutrophil chemotaxis+++GO:0006955///immune response+++GO:0006954///inflammatory response+++GO:0010628///positive regulation of gene expression+++GO:0006952///defense response","platelet factor 4","[PLF4_HUMAN|Reviewed]RecName: Full=Platelet factor 4; Short=PF-4; AltName: Full=C-X-C motif chemokine 4; AltName: Full=Iroplact; AltName: Full=Oncostatin-A; Contains: RecName: Full=Platelet factor 4, short form; AltName: Full=Endothelial cell growth inhibitor {ECO:0000303|PubMed:7644496}; Flags: Precursor;"]
[521,"'ATP5ME'",472,499,396,455.666666666667,"01100///Metabolic pathways+++00190///Oxidative phosphorylation+++04714///Thermogenesis",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005739///mitochondrion+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane","GO:0015078///proton transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity","GO:0042407///cristae formation+++GO:0046034///ATP metabolic process+++GO:0006754///ATP biosynthetic process+++GO:0006811///ion transport+++GO:0015986///ATP synthesis coupled proton transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport","ATP synthase membrane subunit e","[ATP5I_HUMAN|Reviewed]RecName: Full=ATP synthase subunit e, mitochondrial {ECO:0000305}; Short=ATPase subunit e; AltName: Full=ATP synthase membrane subunit e {ECO:0000305}; Contains: RecName: Full=ATP synthase subunit e, mitochondrial, N-terminally processed;"]
[5241,"'PGR'",5,3,15,7.66666666666667,"04114///Oocyte meiosis+++05224///Breast cancer+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0051117///ATPase binding+++GO:0046872///metal ion binding+++GO:0005496///steroid binding+++GO:0043565///sequence-specific DNA binding+++GO:0042802///identical protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005102///signaling receptor binding+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0019899///enzyme binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0001542///ovulation from ovarian follicle+++GO:0007165///signal transduction+++GO:0050678///regulation of epithelial cell proliferation+++GO:0038001///paracrine signaling+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:0007267///cell-cell signaling+++GO:0002070///epithelial cell maturation+++GO:0030879///mammary gland development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010629///negative regulation of gene expression+++GO:0050847///progesterone receptor signaling pathway","progesterone receptor","[PRGR_HUMAN|Reviewed]RecName: Full=Progesterone receptor; Short=PR; AltName: Full=Nuclear receptor subfamily 3 group C member 3;+++[A0A087WXR4_HUMAN|Unreviewed]SubName: Full=Progesterone receptor {ECO:0000313|Ensembl:ENSP00000481227};+++[A0A0J9YVP1_HUMAN|Unreviewed]SubName: Full=Progesterone receptor {ECO:0000313|Ensembl:ENSP00000487607}; Flags: Fragment;+++[Q8NG42_HUMAN|Unreviewed]SubName: Full=Delta 6/2 progesterone receptor {ECO:0000313|EMBL:BAC11013.1}; SubName: Full=Progesterone receptor, isoform CRA_a {ECO:0000313|EMBL:EAW66997.1};+++[Q8NG44_HUMAN|Unreviewed]SubName: Full=Delta 3+6/2 progesterone receptor {ECO:0000313|EMBL:BAC11011.1}; SubName: Full=Progesterone receptor, isoform CRA_e {ECO:0000313|EMBL:EAW67001.1};+++[Q8NG45_HUMAN|Unreviewed]SubName: Full=Progesterone receptor, isoform CRA_f {ECO:0000313|EMBL:EAW67002.1};"]
[5257,"'PHKB'",1338,984,1040,1120.66666666667,"04020///Calcium signaling pathway+++04922///Glucagon signaling pathway+++04910///Insulin signaling pathway","H01760///Hepatic glycogen storage disease+++H01762///Muscle glycogen storage disease+++H01948///Glycogen storage disease type IX+++H00069///Glycogen storage diseases (GSD)","M00146///NADH dehydrogenase (ubiquinone) 1 alpha subcomplex",null,"GO:0005964///phosphorylase kinase complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0004689///phosphorylase kinase activity+++GO:0005516///calmodulin binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0016301///kinase activity","GO:0005977///glycogen metabolic process+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0006091///generation of precursor metabolites and energy","phosphorylase kinase regulatory subunit beta","[KPBB_HUMAN|Reviewed]RecName: Full=Phosphorylase b kinase regulatory subunit beta; Short=Phosphorylase kinase subunit beta;+++[A0A0G2JLB9_HUMAN|Unreviewed]SubName: Full=Phosphorylase b kinase regulatory subunit beta {ECO:0000313|Ensembl:ENSP00000458581}; Flags: Fragment;+++[H3BQ89_HUMAN|Unreviewed]RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123}; Flags: Fragment;+++[H3BV13_HUMAN|Unreviewed]RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123}; Flags: Fragment;+++[I3L0Z1_HUMAN|Unreviewed]RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123}; Flags: Fragment;+++[I3L1N3_HUMAN|Unreviewed]RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123}; Flags: Fragment;+++[I3L213_HUMAN|Unreviewed]RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123}; Flags: Fragment;+++[I3L3F2_HUMAN|Unreviewed]SubName: Full=Phosphorylase b kinase regulatory subunit beta {ECO:0000313|Ensembl:ENSP00000460408}; Flags: Fragment;+++[I3NHZ9_HUMAN|Unreviewed]RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123}; Flags: Fragment;+++[Q6LAJ4_HUMAN|Unreviewed]RecName: Full=Phosphorylase b kinase regulatory subunit {ECO:0000256|RuleBase:RU364123}; Flags: Fragment;"]
[5266,"'PI3'",2,1,5,2.66666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0001533///cornified envelope+++GO:0005829///cytosol","GO:0030280///structural constituent of epidermis+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity+++GO:0007620///copulation+++GO:0019730///antimicrobial humoral response+++GO:0018149///peptide cross-linking+++GO:0070268///cornification+++GO:0010466///negative regulation of peptidase activity","peptidase inhibitor 3","[ELAF_HUMAN|Reviewed]RecName: Full=Elafin; AltName: Full=Elastase-specific inhibitor; Short=ESI; AltName: Full=Peptidase inhibitor 3; Short=PI-3; AltName: Full=Protease inhibitor WAP3; AltName: Full=Skin-derived antileukoproteinase; Short=SKALP; AltName: Full=WAP four-disulfide core domain protein 14; Flags: Precursor;"]
[53,"'ACP2'",2547,2833,2737,2705.66666666667,"04142///Lysosome+++00740///Riboflavin metabolism+++01100///Metabolic pathways","H01113///Acid phosphatase deficiency","M00385///Cul4-DDB1-DDB2 complex","R00548///riboflavin-5-phosphate phosphohydrolase   FMN + H2O <=> Riboflavin + Orthophosphate","GO:0005765///lysosomal membrane+++GO:0016021///integral component of membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0043202///lysosomal lumen+++GO:0070062///extracellular exosome","GO:0016787///hydrolase activity+++GO:0003993///acid phosphatase activity","GO:0007040///lysosome organization+++GO:0016311///dephosphorylation+++GO:0001501///skeletal system development","acid phosphatase 2, lysosomal","[PPAL_HUMAN|Reviewed]RecName: Full=Lysosomal acid phosphatase; Short=LAP; EC=3.1.3.2; Flags: Precursor;+++[B7Z4Z2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52440, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH12728.1};+++[B7Z552_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51033, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH12788.1};+++[B7Z6L8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53923, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH13304.1};+++[B7Z6T8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51106, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH13374.1};+++[B7Z6U3_HUMAN|Unreviewed]SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000434205}; SubName: Full=cDNA FLJ51107, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH13379.1};+++[B7Z7D2_HUMAN|Unreviewed]SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000432205}; SubName: Full=cDNA FLJ51131, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH13568.1};+++[B7Z8T9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52526, highly similar to Lysosomal acid phosphatase {ECO:0000313|EMBL:BAH14075.1};+++[E9PHY0_HUMAN|Unreviewed]SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000436658};+++[E9PKW9_HUMAN|Unreviewed]SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000435261};+++[E9PP23_HUMAN|Unreviewed]SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000436487}; Flags: Fragment;+++[E9PQW9_HUMAN|Unreviewed]SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000432466};+++[E9PQY3_HUMAN|Unreviewed]SubName: Full=Lysosomal acid phosphatase {ECO:0000313|Ensembl:ENSP00000432439};"]
[5310,"'PKD1'",3938,3663,3908,3836.33333333333,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0070062///extracellular exosome+++GO:0016328///lateral plasma membrane+++GO:0005634///nucleus+++GO:0005575///cellular_component+++GO:0000139///Golgi membrane+++GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0031514///motile cilium+++GO:0016021///integral component of membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0034704///calcium channel complex+++GO:0016323///basolateral plasma membrane+++GO:0002133///polycystin complex+++GO:0060170///ciliary membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0034703///cation channel complex+++GO:0005794///Golgi apparatus","GO:0019901///protein kinase binding+++GO:0030246///carbohydrate binding+++GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0005262///calcium channel activity+++GO:0042813///Wnt-activated receptor activity+++GO:0044325///ion channel binding+++GO:0019904///protein domain specific binding","GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0060674///placenta blood vessel development+++GO:0001701///in utero embryonic development+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0001892///embryonic placenta development+++GO:0030155///regulation of cell adhesion+++GO:0072237///metanephric proximal tubule development+++GO:0001889///liver development+++GO:0001822///kidney development+++GO:0060236///regulation of mitotic spindle organization+++GO:0048806///genitalia development+++GO:0006816///calcium ion transport+++GO:0021510///spinal cord development+++GO:0072001///renal system development+++GO:0007259///JAK-STAT cascade+++GO:0006807///nitrogen compound metabolic process+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0072164///mesonephric tubule development+++GO:0001568///blood vessel development+++GO:0098609///cell-cell adhesion+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0030010///establishment of cell polarity+++GO:0007160///cell-matrix adhesion+++GO:0034405///response to fluid shear stress+++GO:0072177///mesonephric duct development+++GO:0001502///cartilage condensation+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0072205///metanephric collecting duct development+++GO:0036303///lymph vessel morphogenesis+++GO:0006611///protein export from nucleus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0018105///peptidyl-serine phosphorylation+++GO:0051290///protein heterotetramerization+++GO:0032092///positive regulation of protein binding+++GO:0198738///cell-cell signaling by wnt+++GO:0060428///lung epithelium development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0048565///digestive tract development+++GO:0016055///Wnt signaling pathway+++GO:0072218///metanephric ascending thin limb development+++GO:0070588///calcium ion transmembrane transport+++GO:0051216///cartilage development+++GO:0021915///neural tube development+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0007507///heart development+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0043588///skin development+++GO:0007050///cell cycle arrest+++GO:0009653///anatomical structure morphogenesis+++GO:0008150///biological_process+++GO:0050982///detection of mechanical stimulus","polycystin 1, transient receptor potential channel interacting","[PKD1_HUMAN|Reviewed]RecName: Full=Polycystin-1; Short=PC1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein; Flags: Precursor;+++[C1JFL5_HUMAN|Unreviewed]SubName: Full=Polysystin 1 {ECO:0000313|EMBL:ACN97591.1}; Flags: Fragment;+++[C1JFL6_HUMAN|Unreviewed]SubName: Full=Polysystin 1 {ECO:0000313|EMBL:ACN97592.1}; Flags: Fragment;+++[C1JFL7_HUMAN|Unreviewed]SubName: Full=Polysystin 1 {ECO:0000313|EMBL:ACN97593.1}; Flags: Fragment;+++[H3BQF4_HUMAN|Unreviewed]SubName: Full=Polycystin-1 {ECO:0000313|Ensembl:ENSP00000455753}; Flags: Fragment;+++[H3BSE8_HUMAN|Unreviewed]SubName: Full=Polycystin-1 {ECO:0000313|Ensembl:ENSP00000456670}; Flags: Fragment;+++[H3BSE9_HUMAN|Unreviewed]SubName: Full=Polycystin-1 {ECO:0000313|Ensembl:ENSP00000456672}; Flags: Fragment;+++[H3BTE0_HUMAN|Unreviewed]SubName: Full=Polycystin-1 {ECO:0000313|Ensembl:ENSP00000457132}; Flags: Fragment;+++[H3BTG3_HUMAN|Unreviewed]SubName: Full=Polycystin-1 {ECO:0000313|Ensembl:ENSP00000457162}; Flags: Fragment;+++[H3BV77_HUMAN|Unreviewed]SubName: Full=Polycystin-1 {ECO:0000313|Ensembl:ENSP00000457984}; Flags: Fragment;+++[I3L4N0_HUMAN|Unreviewed]SubName: Full=Polycystin-1 {ECO:0000313|Ensembl:ENSP00000461391}; Flags: Fragment;+++[O75276_HUMAN|Unreviewed]SubName: Full=PKD1 {ECO:0000313|EMBL:AAC34211.1}; Flags: Fragment;+++[Q15142_HUMAN|Unreviewed]SubName: Full=Polycystic kidney disease-associated protein {ECO:0000313|EMBL:AAB59488.1};"]
[5334,"'PLCL1'",15,4,10,9.66666666666667,"04727///GABAergic synapse",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0050811///GABA receptor binding+++GO:0070679///inositol 1,4,5 trisphosphate binding+++GO:0004629///phospholipase C activity+++GO:0016787///hydrolase activity+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0008081///phosphoric diester hydrolase activity","GO:0016042///lipid catabolic process+++GO:0035556///intracellular signal transduction+++GO:1900122///positive regulation of receptor binding+++GO:0007165///signal transduction+++GO:0006629///lipid metabolic process+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0120163///negative regulation of cold-induced thermogenesis","phospholipase C like 1 (inactive)","[PLCL1_HUMAN|Reviewed]RecName: Full=Inactive phospholipase C-like protein 1; Short=PLC-L1; AltName: Full=Phospholipase C-deleted in lung carcinoma; AltName: Full=Phospholipase C-related but catalytically inactive protein; Short=PRIP;+++[A0A0A0MT40_HUMAN|Unreviewed]RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133}; EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133};+++[F8WAR2_HUMAN|Unreviewed]SubName: Full=Inactive phospholipase C-like protein 1 {ECO:0000313|Ensembl:ENSP00000410488};+++[H3BUD4_HUMAN|Unreviewed]RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133}; EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133}; Flags: Fragment;"]
[5335,"'PLCG1'",1829,1533,1691,1684.33333333333,"05200///Pathways in cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++04360///Axon guidance+++04370///VEGF signaling pathway+++04660///T cell receptor signaling pathway+++04919///Thyroid hormone signaling pathway+++04072///Phospholipase D signaling pathway+++05231///Choline metabolism in cancer+++04070///Phosphatidylinositol signaling system+++04666///Fc gamma R-mediated phagocytosis+++04659///Th17 cell differentiation+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04020///Calcium signaling pathway+++04064///NF-kappa B signaling pathway+++04014///Ras signaling pathway+++04658///Th1 and Th2 cell differentiation+++04650///Natural killer cell mediated cytotoxicity+++05206///MicroRNAs in cancer+++05223///Non-small cell lung cancer+++04664///Fc epsilon RI signaling pathway+++05110///Vibrio cholerae infection+++04012///ErbB signaling pathway+++04015///Rap1 signaling pathway+++04670///Leukocyte transendothelial migration+++04066///HIF-1 signaling pathway+++04722///Neurotrophin signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04933///AGE-RAGE signaling pathway in diabetic complications+++05225///Hepatocellular carcinoma+++05205///Proteoglycans in cancer+++04750///Inflammatory mediator regulation of TRP channels+++05214///Glioma+++05169///Epstein-Barr virus infection+++00562///Inositol phosphate metabolism+++01100///Metabolic pathways",null,"M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R10952///1-phosphatidyl-1D-myo-inositol-4-phosphate inositolbisphosphohydrolase   1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + 1,2-Diacyl-sn-glycerol+++R03332///1-Phosphatidyl-D-myo-inositol inositolphosphohydrolase   1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol+++R03435///1-Phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase   1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol","GO:0008180///COP9 signalosome+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0001726///ruffle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005911///cell-cell junction+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030027///lamellipodium","GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0005168///neurotrophin TRKA receptor binding+++GO:0035254///glutamate receptor binding+++GO:0016787///hydrolase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0005515///protein binding+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004629///phospholipase C activity+++GO:0005509///calcium ion binding+++GO:0030971///receptor tyrosine kinase binding","GO:0043647///inositol phosphate metabolic process+++GO:0016477///cell migration+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0035556///intracellular signal transduction+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:0050852///T cell receptor signaling pathway+++GO:0006816///calcium ion transport+++GO:0006629///lipid metabolic process+++GO:0007165///signal transduction+++GO:0007411///axon guidance+++GO:0045766///positive regulation of angiogenesis+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0016042///lipid catabolic process+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0009395///phospholipid catabolic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0016032///viral process+++GO:0050900///leukocyte migration+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0010863///positive regulation of phospholipase C activity+++GO:0019722///calcium-mediated signaling+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0001701///in utero embryonic development+++GO:0007202///activation of phospholipase C activity+++GO:0010634///positive regulation of epithelial cell migration","phospholipase C gamma 1","[PLCG1_HUMAN|Reviewed]RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; EC=3.1.4.11; AltName: Full=PLC-148; AltName: Full=Phosphoinositide phospholipase C-gamma-1; AltName: Full=Phospholipase C-II; Short=PLC-II; AltName: Full=Phospholipase C-gamma-1; Short=PLC-gamma-1;+++[A0A0D9SEK2_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 {ECO:0000313|Ensembl:ENSP00000485760}; Flags: Fragment;+++[M0QX77_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 {ECO:0000313|Ensembl:ENSP00000468958}; Flags: Fragment;+++[Q4LE43_HUMAN|Unreviewed]RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133}; EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133}; Flags: Fragment;+++[Q9UFY1_HUMAN|Unreviewed]RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133}; EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133}; Flags: Fragment;+++[V9GY63_HUMAN|Unreviewed]RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133}; EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133}; Flags: Fragment;+++[V9GY71_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 {ECO:0000313|Ensembl:ENSP00000476454}; Flags: Fragment;+++[V9GYH5_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 {ECO:0000313|Ensembl:ENSP00000476757}; Flags: Fragment;"]
[5354,"'PLP1'",0,1,1,0.666666666666667,null,"H00266///Hereditary spastic paraplegia (SPG)+++H00679///Hypomyelinating leukodystrophy",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0005198///structural molecule activity+++GO:0019911///structural constituent of myelin sheath","GO:0010628///positive regulation of gene expression+++GO:0022010///central nervous system myelination+++GO:0010001///glial cell differentiation+++GO:0007229///integrin-mediated signaling pathway+++GO:0042759///long-chain fatty acid biosynthetic process+++GO:0014002///astrocyte development+++GO:0021762///substantia nigra development+++GO:0008366///axon ensheathment+++GO:0006954///inflammatory response+++GO:0042552///myelination+++GO:0061564///axon development+++GO:0007268///chemical synaptic transmission","proteolipid protein 1","[MYPR_HUMAN|Reviewed]RecName: Full=Myelin proteolipid protein; Short=PLP; AltName: Full=Lipophilin;+++[A0A0S2Z4D4_HUMAN|Unreviewed]SubName: Full=Proteolipid protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33719.1}; Flags: Fragment;+++[A8K9L3_HUMAN|Unreviewed]SubName: Full=Proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated), isoform CRA_b {ECO:0000313|EMBL:EAW54691.1}; SubName: Full=Proteolipid protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33720.1}; SubName: Full=cDNA FLJ77822, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA {ECO:0000313|EMBL:BAF85417.1}; SubName: Full=cDNA, FLJ92659, highly similar to Homo sapiens proteolipid protein 1 (Pelizaeus-Merzbacher disease,spastic paraplegia 2, uncomplicated) (PLP1), mRNA {ECO:0000313|EMBL:BAG35261.1};+++[B1B1G1_HUMAN|Unreviewed]SubName: Full=Myelin proteolipid protein {ECO:0000313|Ensembl:ENSP00000393391}; Flags: Fragment;+++[B1B1G2_HUMAN|Unreviewed]SubName: Full=Myelin proteolipid protein {ECO:0000313|Ensembl:ENSP00000391853}; Flags: Fragment;+++[B1B1G3_HUMAN|Unreviewed]SubName: Full=Myelin proteolipid protein {ECO:0000313|Ensembl:ENSP00000403335}; Flags: Fragment;+++[B1B1G4_HUMAN|Unreviewed]SubName: Full=Myelin proteolipid protein {ECO:0000313|Ensembl:ENSP00000413931}; Flags: Fragment;+++[B1B1G6_HUMAN|Unreviewed]SubName: Full=Myelin proteolipid protein {ECO:0000313|Ensembl:ENSP00000409802}; Flags: Fragment;+++[B4DI30_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54051, highly similar to Myelin proteolipid protein {ECO:0000313|EMBL:BAG58342.1};"]
[5364,"'PLXNB1'",10647,10159,9949,10251.6666666667,"04360///Axon guidance",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0002116///semaphorin receptor complex","GO:0005096///GTPase activator activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0038023///signaling receptor activity+++GO:0017154///semaphorin receptor activity+++GO:0032794///GTPase activating protein binding+++GO:0030215///semaphorin receptor binding+++GO:0005515///protein binding","GO:1900220///semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis+++GO:0048812///neuron projection morphogenesis+++GO:0043087///regulation of GTPase activity+++GO:0050772///positive regulation of axonogenesis+++GO:0043547///positive regulation of GTPase activity+++GO:0016477///cell migration+++GO:0008360///regulation of cell shape+++GO:0033689///negative regulation of osteoblast proliferation+++GO:0007162///negative regulation of cell adhesion+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043931///ossification involved in bone maturation+++GO:0051493///regulation of cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0071526///semaphorin-plexin signaling pathway+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction","plexin B1","[PLXB1_HUMAN|Reviewed]RecName: Full=Plexin-B1; AltName: Full=Semaphorin receptor SEP; Flags: Precursor;+++[A0A0B6XK48_HUMAN|Unreviewed]SubName: Full=Plexin B1 {ECO:0000313|EMBL:CEH24705.1}; Flags: Fragment;+++[A1A4U0_HUMAN|Unreviewed]SubName: Full=PLXNB1 protein {ECO:0000313|EMBL:AAI28095.1};"]
[538,"'ATP7A'",189,136,145,156.666666666667,"01524///Platinum drug resistance+++04016///MAPK signaling pathway - plant","H00210///Wilson disease+++H00856///Distal hereditary motor neuropathies (dHMN)+++H01859///Occipital horn syndrome+++H00209///Menkes syndrome+++H00455///Spinal muscular atrophy (SMA)",null,"R00086///ATP phosphohydrolase   ATP + H2O <=> ADP + Orthophosphate","GO:0005770///late endosome+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0043204///perikaryon+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0031526///brush border membrane+++GO:0045121///membrane raft+++GO:0030141///secretory granule+++GO:0005783///endoplasmic reticulum+++GO:0030670///phagocytic vesicle membrane+++GO:0016324///apical plasma membrane+++GO:0005902///microvillus+++GO:0031252///cell leading edge+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0030140///trans-Golgi network transport vesicle+++GO:0005802///trans-Golgi network+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0043025///neuronal cell body","GO:0004008///copper-exporting ATPase activity+++GO:0005515///protein binding+++GO:0048365///Rac GTPase binding+++GO:0016532///superoxide dismutase copper chaperone activity+++GO:0043682///copper-transporting ATPase activity+++GO:0005375///copper ion transmembrane transporter activity+++GO:0046872///metal ion binding+++GO:0005507///copper ion binding+++GO:0000166///nucleotide binding+++GO:0019829///cation-transporting ATPase activity+++GO:0016787///hydrolase activity+++GO:0005524///ATP binding+++GO:0051087///chaperone binding+++GO:1903136///cuprous ion binding+++GO:0032767///copper-dependent protein binding","GO:0007626///locomotory behavior+++GO:0042417///dopamine metabolic process+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0060003///copper ion export+++GO:0045793///positive regulation of cell size+++GO:0042093///T-helper cell differentiation+++GO:0043588///skin development+++GO:0010041///response to iron(III) ion+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0001568///blood vessel development+++GO:0007595///lactation+++GO:0042415///norepinephrine metabolic process+++GO:0071456///cellular response to hypoxia+++GO:0071236///cellular response to antibiotic+++GO:0034760///negative regulation of iron ion transmembrane transport+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0006568///tryptophan metabolic process+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006811///ion transport+++GO:0030199///collagen fibril organization+++GO:0071281///cellular response to iron ion+++GO:0010273///detoxification of copper ion+++GO:0006878///cellular copper ion homeostasis+++GO:0015677///copper ion import+++GO:0006812///cation transport+++GO:0051542///elastin biosynthetic process+++GO:0043473///pigmentation+++GO:0042428///serotonin metabolic process+++GO:0010288///response to lead ion+++GO:0021954///central nervous system neuron development+++GO:0046688///response to copper ion+++GO:0010468///regulation of gene expression+++GO:0051216///cartilage development+++GO:0002082///regulation of oxidative phosphorylation+++GO:0042414///epinephrine metabolic process+++GO:0048286///lung alveolus development+++GO:0071280///cellular response to copper ion+++GO:0048812///neuron projection morphogenesis+++GO:0006584///catecholamine metabolic process+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0071230///cellular response to amino acid stimulus+++GO:0030001///metal ion transport+++GO:0071284///cellular response to lead ion+++GO:1903036///positive regulation of response to wounding+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0030198///extracellular matrix organization+++GO:0031069///hair follicle morphogenesis+++GO:0018205///peptidyl-lysine modification+++GO:1904959///regulation of cytochrome-c oxidase activity+++GO:0071276///cellular response to cadmium ion+++GO:0010043///response to zinc ion+++GO:0007005///mitochondrion organization+++GO:0043085///positive regulation of catalytic activity+++GO:0071279///cellular response to cobalt ion+++GO:0048251///elastic fiber assembly+++GO:0043086///negative regulation of catalytic activity+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0006825///copper ion transport+++GO:0001974///blood vessel remodeling+++GO:0001701///in utero embryonic development+++GO:0021860///pyramidal neuron development+++GO:0010042///response to manganese ion+++GO:0001889///liver development+++GO:0019430///removal of superoxide radicals","ATPase copper transporting alpha","[ATP7A_HUMAN|Reviewed]RecName: Full=Copper-transporting ATPase 1; EC=3.6.3.54; AltName: Full=Copper pump 1; AltName: Full=Menkes disease-associated protein;+++[A0A2R8YD60_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 1 {ECO:0000313|Ensembl:ENSP00000493605};+++[B4DRW0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58125, highly similar to Copper-transporting ATPase 1 {ECO:0000313|EMBL:BAG61422.1};+++[Q762B6_HUMAN|Unreviewed]SubName: Full=ATP7A protein {ECO:0000313|EMBL:BAC82353.1};"]
[5394,"'EXOSC10'",1074,1004,1044,1040.66666666667,"03018///RNA degradation",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0035327///transcriptionally active chromatin+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005654///nucleoplasm","GO:0004532///exoribonuclease activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0004518///nuclease activity+++GO:0005515///protein binding+++GO:0004527///exonuclease activity+++GO:0070034///telomerase RNA binding+++GO:0003676///nucleic acid binding+++GO:0008408///3'-5' exonuclease activity+++GO:0000166///nucleotide binding","GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0044237///cellular metabolic process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0006364///rRNA processing+++GO:1904872///regulation of telomerase RNA localization to Cajal body+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0006396///RNA processing+++GO:0071028///nuclear mRNA surveillance+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0071044///histone mRNA catabolic process+++GO:0000460///maturation of 5.8S rRNA+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0071048///nuclear retention of unspliced pre-mRNA at the site of transcription+++GO:0071034///CUT catabolic process","exosome component 10","[EXOSX_HUMAN|Reviewed]RecName: Full=Exosome component 10 {ECO:0000305}; EC=3.1.13.-; AltName: Full=Autoantigen PM/Scl 2; AltName: Full=P100 polymyositis-scleroderma overlap syndrome-associated autoantigen; AltName: Full=Polymyositis/scleroderma autoantigen 100 kDa; Short=PM/Scl-100; AltName: Full=Polymyositis/scleroderma autoantigen 2;+++[K7EJ37_HUMAN|Unreviewed]SubName: Full=Exosome component 10 {ECO:0000313|Ensembl:ENSP00000465008};+++[L8E6Y6_HUMAN|Unreviewed]SubName: Full=Alternative protein EXOSC10 {ECO:0000313|EMBL:CCQ43005.1};+++[Q96G78_HUMAN|Unreviewed]SubName: Full=EXOSC10 protein {ECO:0000313|EMBL:AAH09908.2}; Flags: Fragment;"]
[54033,"'RBM11'",3,6,11,6.66666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0008266///poly(U) RNA binding+++GO:0003723///RNA binding+++GO:0042803///protein homodimerization activity+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding","GO:0030154///cell differentiation+++GO:0034599///cellular response to oxidative stress+++GO:0007275///multicellular organism development+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 11","[RBM11_HUMAN|Reviewed]RecName: Full=Splicing regulator RBM11; AltName: Full=RNA-binding motif protein 11;+++[D3DSC2_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 11, isoform CRA_b {ECO:0000313|EMBL:EAX10063.1};"]
[54148,"'MRPL39'",89,90,77,85.3333333333333,{"$nulls":4},"GO:0005761///mitochondrial ribosome+++GO:0005840///ribosome+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005743///mitochondrial inner membrane","GO:0000166///nucleotide binding+++GO:0003723///RNA binding","GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination","mitochondrial ribosomal protein L39","[RM39_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L39, mitochondrial; Short=L39mt; Short=MRP-L39; AltName: Full=39S ribosomal protein L5, mitochondrial; Short=L5mt; Short=MRP-L5; AltName: Full=Mitochondrial large ribosomal subunit protein mL39 {ECO:0000303|PubMed:25278503};+++[C9JG87_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L39, mitochondrial {ECO:0000313|Ensembl:ENSP00000404426}; Flags: Fragment;"]
[54212,"'SNTG1'",1,0,0,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0032587///ruffle membrane+++GO:0005737///cytoplasm+++GO:0016013///syntrophin complex+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0005198///structural molecule activity+++GO:0003779///actin binding+++GO:0008022///protein C-terminus binding","GO:0007154///cell communication","syntrophin gamma 1","[SNTG1_HUMAN|Reviewed]RecName: Full=Gamma-1-syntrophin; Short=G1SYN; AltName: Full=Syntrophin-4; Short=SYN4;+++[A0A024R7Y0_HUMAN|Unreviewed]SubName: Full=Syntrophin, gamma 1, isoform CRA_a {ECO:0000313|EMBL:EAW86705.1};+++[A0A2R8Y457_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000493658};+++[A0A2R8Y5G8_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000494442};+++[A0A2R8Y5T2_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000494713};+++[A0A2R8Y631_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000494929};+++[A0A2R8Y668_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000494985};+++[A0A2R8Y6P6_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000495470};+++[A0A2R8Y7J9_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000496330};+++[A0A2R8Y7L6_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000496116};+++[A0A2R8Y7Z5_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000496525};+++[A0A2R8YDV6_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000494958};+++[A0A2R8YEF7_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000495550};+++[A0A2R8YF28_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000494759};+++[A0A2R8YFF5_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000495100};+++[A0A2R8YGL5_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000496147};+++[B2RA84_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94759, highly similar to Homo sapiens syntrophin, gamma 1 (SNTG1), mRNA {ECO:0000313|EMBL:BAG36781.1};+++[E5RHN6_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000428558};+++[E5RIN0_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000429363}; Flags: Fragment;+++[H0YC21_HUMAN|Unreviewed]SubName: Full=Gamma-1-syntrophin {ECO:0000313|Ensembl:ENSP00000430748}; Flags: Fragment;"]
[5434,"'POLR2E'",2098,2420,2338,2285.33333333333,"03020///RNA polymerase+++00230///Purine metabolism+++01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++05169///Epstein-Barr virus infection+++05016///Huntington's disease+++00240///Pyrimidine metabolism",null,"M00180///RNA polymerase II, eukaryotes+++M00182///RNA polymerase I, eukaryotes+++M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA","GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005736///RNA polymerase I complex+++GO:0005665///RNA polymerase II, core complex+++GO:0005654///nucleoplasm+++GO:0005666///RNA polymerase III complex","GO:0003677///DNA binding+++GO:0001055///RNA polymerase II activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0001054///RNA polymerase I activity+++GO:0005515///protein binding+++GO:0001056///RNA polymerase III activity","GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006351///transcription, DNA-templated+++GO:0006370///7-methylguanosine mRNA capping+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0060964///regulation of gene silencing by miRNA+++GO:0016070///RNA metabolic process+++GO:0006363///termination of RNA polymerase I transcription+++GO:0016032///viral process+++GO:0006383///transcription by RNA polymerase III+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0045815///positive regulation of gene expression, epigenetic","RNA polymerase II subunit E","[RPAB1_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1; Short=RNA polymerases I, II, and III subunit ABC1; AltName: Full=DNA-directed RNA polymerase II 23 kDa polypeptide; AltName: Full=DNA-directed RNA polymerase II subunit E; AltName: Full=RPB5 homolog; AltName: Full=XAP4;+++[A0A087WVN5_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1 {ECO:0000313|Ensembl:ENSP00000479560}; Flags: Fragment;+++[A0A087WVZ9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1 {ECO:0000313|Ensembl:ENSP00000479813};+++[A0A087WWX0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1 {ECO:0000313|Ensembl:ENSP00000480562}; Flags: Fragment;+++[A0A0A0MQR7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1 {ECO:0000313|Ensembl:ENSP00000215587};+++[B4DJ89_HUMAN|Unreviewed]SubName: Full=Polymerase (RNA) II (DNA directed) polypeptide E, 25kDa, isoform CRA_c {ECO:0000313|EMBL:EAW69550.1}; SubName: Full=cDNA FLJ55074, highly similar to DNA-directed RNA polymerase II 23 kDa polypeptide {ECO:0000313|EMBL:BAG58751.1};+++[K7EJ87_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1 {ECO:0000313|Ensembl:ENSP00000465066};+++[K7EQN2_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC1 {ECO:0000313|Ensembl:ENSP00000467905};"]
[54414,"'SIAE'",665,568.17,801,678.056666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005764///lysosome+++GO:0005576///extracellular region","GO:0016787///hydrolase activity+++GO:0001681///sialate O-acetylesterase activity+++GO:0052689///carboxylic ester hydrolase activity","GO:0002682///regulation of immune system process+++GO:0005975///carbohydrate metabolic process","sialic acid acetylesterase","[SIAE_HUMAN|Reviewed]RecName: Full=Sialate O-acetylesterase; EC=3.1.1.53; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor;"]
[5443,"'POMC'",21,13,19,17.6666666666667,"04925///Aldosterone synthesis and secretion+++04916///Melanogenesis+++04920///Adipocytokine signaling pathway+++04934///Cushing's syndrome+++04927///Cortisol synthesis and secretion","H02106///Genetic obesity",null,null,"GO:0034774///secretory granule lumen+++GO:0030141///secretory granule+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0005782///peroxisomal matrix+++GO:0005576///extracellular region+++GO:0005777///peroxisome","GO:0031781///type 3 melanocortin receptor binding+++GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity+++GO:0005102///signaling receptor binding+++GO:0031782///type 4 melanocortin receptor binding+++GO:0070996///type 1 melanocortin receptor binding","GO:0008217///regulation of blood pressure+++GO:0070965///positive regulation of neutrophil mediated killing of fungus+++GO:0042593///glucose homeostasis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006091///generation of precursor metabolites and energy+++GO:0010469///regulation of signaling receptor activity+++GO:0070873///regulation of glycogen metabolic process+++GO:0032098///regulation of appetite+++GO:0007218///neuropeptide signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0033059///cellular pigmentation+++GO:0007165///signal transduction+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:2000852///regulation of corticosterone secretion+++GO:0007267///cell-cell signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II","proopiomelanocortin","[COLI_HUMAN|Reviewed]RecName: Full=Pro-opiomelanocortin; Short=POMC; AltName: Full=Corticotropin-lipotropin; Contains: RecName: Full=NPP; Contains: RecName: Full=Melanotropin gamma; AltName: Full=Gamma-MSH; Contains: RecName: Full=Potential peptide; Contains: RecName: Full=Corticotropin; AltName: Full=Adrenocorticotropic hormone; Short=ACTH; Contains: RecName: Full=Melanocyte-stimulating hormone alpha; Short=Alpha-MSH; AltName: Full=Melanotropin alpha; Contains: RecName: Full=Corticotropin-like intermediary peptide; Short=CLIP; Contains: RecName: Full=Lipotropin beta; AltName: Full=Beta-LPH; Contains: RecName: Full=Lipotropin gamma; AltName: Full=Gamma-LPH; Contains: RecName: Full=Melanocyte-stimulating hormone beta; Short=Beta-MSH; AltName: Full=Melanotropin beta; Contains: RecName: Full=Beta-endorphin; Contains: RecName: Full=Met-enkephalin; Flags: Precursor;+++[E9PHK5_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|Ensembl:ENSP00000387993}; Flags: Fragment;+++[K7QX41_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77536.1}; Flags: Fragment;+++[K7QX44_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77541.1}; Flags: Fragment;+++[K7QX47_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77546.1}; Flags: Fragment;+++[K7QX51_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77551.1}; Flags: Fragment;+++[K7QZC2_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77533.1}; Flags: Fragment;+++[K7QZC9_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77543.1}; Flags: Fragment;+++[K7QZD2_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77548.1}; Flags: Fragment;+++[K7R2I7_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77540.1}; Flags: Fragment;+++[K7R2J5_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77550.1}; Flags: Fragment;+++[K7R8V2_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77539.1}; Flags: Fragment;+++[K7R8V7_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77544.1}; Flags: Fragment;+++[K7R8W0_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77549.1}; Flags: Fragment;+++[K7RMD8_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77537.1}; Flags: Fragment;+++[K7RME8_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77547.1}; Flags: Fragment;+++[K7RMF2_HUMAN|Unreviewed]SubName: Full=Pro-opiomelanocortin {ECO:0000313|EMBL:AFV77552.1}; Flags: Fragment;+++[Q6FHC8_HUMAN|Unreviewed]SubName: Full=POMC protein {ECO:0000313|EMBL:CAG46625.1}; Flags: Fragment;+++[Q6LDP0_HUMAN|Unreviewed]SubName: Full=Proopiomelanocortin {ECO:0000313|EMBL:AAA60139.1}; Flags: Fragment;"]
[54470,"'ARMCX6'",469,431,374,424.666666666667,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion",null,null,"armadillo repeat containing X-linked 6","[ARMX6_HUMAN|Reviewed]RecName: Full=Protein ARMCX6;+++[A0A024RCG5_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 6, isoform CRA_b {ECO:0000313|EMBL:EAX02879.1};"]
[54472,"'TOLLIP'",1188,1210,1189,1195.66666666667,"04620///Toll-like receptor signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0035580///specific granule lumen+++GO:0045323///interleukin-1 receptor complex+++GO:0016604///nuclear body+++GO:0035578///azurophil granule lumen+++GO:0005737///cytoplasm+++GO:0045092///interleukin-18 receptor complex","GO:0005150///interleukin-1, type I receptor binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035325///Toll-like receptor binding+++GO:0043130///ubiquitin binding+++GO:0032183///SUMO binding+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0030855///epithelial cell differentiation+++GO:0045087///innate immune response+++GO:0035556///intracellular signal transduction+++GO:0006954///inflammatory response+++GO:0045321///leukocyte activation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0036010///protein localization to endosome+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0033235///positive regulation of protein sumoylation+++GO:0043312///neutrophil degranulation+++GO:0007267///cell-cell signaling","toll interacting protein","[TOLIP_HUMAN|Reviewed]RecName: Full=Toll-interacting protein;+++[B3KR28_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33531 fis, clone BRAMY2007255, highly similar to Toll-interacting protein {ECO:0000313|EMBL:BAG52240.1};+++[E7EN89_HUMAN|Unreviewed]SubName: Full=Toll interacting protein, isoform CRA_b {ECO:0000313|EMBL:EAX02435.1}; SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000263646};+++[E9PNS3_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000432778};+++[E9PP67_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000436393};+++[E9PQ25_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000434494}; Flags: Fragment;+++[F2Z2Y8_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000432668};+++[Q6FIE9_HUMAN|Unreviewed]SubName: Full=TOLLIP protein {ECO:0000313|EMBL:CAG38508.1}; SubName: Full=Toll interacting protein {ECO:0000313|EMBL:AAX22229.1}; SubName: Full=Toll interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAX02433.1}; SubName: Full=cDNA, FLJ96670, Homo sapiens toll interacting protein (TOLLIP), mRNA {ECO:0000313|EMBL:BAG37964.1};+++[Q8N8J5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39374 fis, clone PEBLM2008576, highly similar to Homo sapiens TOLLIP protein {ECO:0000313|EMBL:BAC04844.1};"]
[54499,"'TMCO1'",1157,1079,1157,1131,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0005262///calcium channel activity","GO:0070588///calcium ion transmembrane transport+++GO:0006811///ion transport+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0006983///ER overload response+++GO:0006816///calcium ion transport","transmembrane and coiled-coil domains 1","[TMCO1_HUMAN|Reviewed]RecName: Full=Calcium load-activated calcium channel {ECO:0000305|PubMed:27212239}; Short=CLAC channel {ECO:0000305|PubMed:27212239}; AltName: Full=Transmembrane and coiled-coil domain-containing protein 1 {ECO:0000305}; AltName: Full=Transmembrane and coiled-coil domains protein 4 {ECO:0000305}; AltName: Full=Xenogeneic cross-immune protein PCIA3 {ECO:0000303|Ref.2};+++[B7Z591_HUMAN|Unreviewed]RecName: Full=Calcium load-activated calcium channel {ECO:0000256|PIRNR:PIRNR023322}; Short=CLAC channel {ECO:0000256|PIRNR:PIRNR023322};+++[J3KS45_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000462300}; Flags: Fragment;+++[J3KTQ7_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000463105}; SubName: Full=Transmembrane and coiled-coil domains 1, isoform CRA_d {ECO:0000313|EMBL:EAW90765.1};+++[J3QQY2_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000463951}; SubName: Full=Transmembrane and coiled-coil domains 1, isoform CRA_c {ECO:0000313|EMBL:EAW90764.1};+++[J3QRB3_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000464127}; Flags: Fragment;+++[J9JIE6_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000356856}; SubName: Full=Transmembrane and coiled-coil domains 1, isoform CRA_b {ECO:0000313|EMBL:EAW90763.1};+++[L8EA41_HUMAN|Unreviewed]SubName: Full=Alternative protein TMCO1 {ECO:0000313|EMBL:CCQ43611.1};"]
[54520,"'CCDC93'",1053,680,725,819.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005768///endosome+++GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding","GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport","coiled-coil domain containing 93","[CCD93_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 93;+++[F8W9X7_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 93 {ECO:0000313|Ensembl:ENSP00000324135};+++[H7C050_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 93 {ECO:0000313|Ensembl:ENSP00000392989}; Flags: Fragment;"]
[54542,"'RC3H2'",635,380,494,503,{"$nulls":4},"GO:0016020///membrane+++GO:0009986///cell surface+++GO:0000932///P-body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm","GO:0003729///mRNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0035613///RNA stem-loop binding+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding","GO:0000209///protein polyubiquitination+++GO:0050852///T cell receptor signaling pathway+++GO:0009791///post-embryonic development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010608///posttranscriptional regulation of gene expression+++GO:2000628///regulation of miRNA metabolic process+++GO:0016567///protein ubiquitination+++GO:0061470///T follicular helper cell differentiation+++GO:0042098///T cell proliferation+++GO:0048286///lung alveolus development+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0060173///limb development+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:0010468///regulation of gene expression+++GO:0035264///multicellular organism growth+++GO:0043029///T cell homeostasis+++GO:0001782///B cell homeostasis","ring finger and CCCH-type domains 2","[RC3H2_HUMAN|Reviewed]RecName: Full=Roquin-2; EC=2.3.2.27 {ECO:0000269|PubMed:26249698}; AltName: Full=Membrane-associated nucleic acid-binding protein; AltName: Full=RING finger and CCCH-type zinc finger domain-containing protein 2; AltName: Full=RING finger protein 164; AltName: Full=RING-type E3 ubiquitin transferase Roquin-2 {ECO:0000305};+++[A0A024R899_HUMAN|Unreviewed]SubName: Full=Membrane associated DNA binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW87550.1};+++[A6NHN2_HUMAN|Unreviewed]SubName: Full=Roquin-2 {ECO:0000313|Ensembl:ENSP00000335150};+++[H0Y5D9_HUMAN|Unreviewed]SubName: Full=Roquin-2 {ECO:0000313|Ensembl:ENSP00000398081}; Flags: Fragment;+++[Q4VXB2_HUMAN|Unreviewed]SubName: Full=Roquin-2 {ECO:0000313|Ensembl:ENSP00000381663}; Flags: Fragment;"]
[54578,"'UGT1A6'",1,2,0,1,"01100///Metabolic pathways+++00982///Drug metabolism - cytochrome P450+++05204///Chemical carcinogenesis+++00140///Steroid hormone biosynthesis+++00983///Drug metabolism - other enzymes+++00040///Pentose and glucuronate interconversions+++00053///Ascorbate and aldarate metabolism+++01110///Biosynthesis of secondary metabolites+++00980///Metabolism of xenobiotics by cytochrome P450+++00860///Porphyrin and chlorophyll metabolism+++00830///Retinol metabolism","H01593///Osteoporosis+++H00208///Hyperbilirubinemia+++H02152///Transient familial neonatal hyperbilirubinemia+++H02054///Crigler-Najjar syndrome+++H02055///Gilbert syndrome","M00129///Ascorbate biosynthesis, animals, glucose-1P => ascorbate+++M00014///Glucuronate pathway (uronate pathway)","R08262///Morphine + UDP-glucuronate <=> Morphine-3-glucuronide + UDP+++R08263///Morphine + UDP-glucuronate <=> Morphine-6-glucuronide + UDP+++R04352///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Etiocholanolone + UDP-glucuronate <=> Etiocholan-3alpha-ol-17-one 3-glucuronide + UDP+++R08259///SN-38 + UDP-glucuronate <=> SN38 glucuronide + UDP+++R02389///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   2 UDP-glucuronate + Bilirubin <=> 2 UDP + Bilirubin beta-diglucuronide+++R08615///UDP-glucuronate glucuronohydrolase   UDP-glucuronate + H2O <=> UDP + D-Glucuronate+++R04683///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   UDP-glucuronate + Estriol <=> UDP + 16-Glucuronide-estriol+++R02502///17beta-hydroxysteroid UDP-glucuronosyltransferase   Testosterone + UDP-glucuronate <=> Testosterone glucuronide + UDP+++R09428///UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)   UDP-glucuronate + Acceptor <=> UDP + Acceptor beta-D-glucuronoside+++R07106///UDP-glucuronate beta-D-glucuronosyltransferase   Trichloroethanol + UDP-glucuronate <=> Trichloroethanol glucuronide + UDP+++R09426///4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide + UDP+++R04353///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   2-Methoxyestrone + UDP-glucuronate <=> 2-Methoxyestrone 3-glucuronide + UDP+++R04354///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   2-Methoxy-17beta-estradiol + UDP-glucuronate <=> 2-Methoxy-estradiol-17beta 3-glucuronide + UDP+++R03091///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Estradiol-17beta + UDP-glucuronate <=> Estradiol-17beta 3-glucuronide + UDP+++R02478///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Androsterone + UDP-glucuronate <=> Androsterone glucuronide + UDP+++R08261///UDP-glucuronate + Codeine <=> UDP + Codeine-6-glucuronide+++R01383///UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific)   UDP-glucuronate + ROH <=> UDP + beta-D-Glucuronoside+++R02902///Retinoate + UDP-glucuronate <=> all-trans-Retinoyl-beta-glucuronide + UDP+++R02358///UDPglucuronate beta-D-glucuronosyltransferase(acceptor-unspecific)   Estrone + UDP-glucuronate <=> Estrone glucuronide + UDP+++R09427///4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol + UDP-glucuronate <=> NNAL-N-glucuronide + UDP","GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016758///transferase activity, transferring hexosyl groups+++GO:0008194///UDP-glycosyltransferase activity+++GO:0046982///protein heterodimerization activity+++GO:0015020///glucuronosyltransferase activity+++GO:0019899///enzyme binding+++GO:0001972///retinoic acid binding+++GO:0042803///protein homodimerization activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0052696///flavonoid glucuronidation+++GO:0045922///negative regulation of fatty acid metabolic process+++GO:1904224///negative regulation of glucuronosyltransferase activity+++GO:2001030///negative regulation of cellular glucuronidation+++GO:0052697///xenobiotic glucuronidation+++GO:0017144///drug metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0052695///cellular glucuronidation","UDP glucuronosyltransferase family 1 member A6","[UD16_HUMAN|Reviewed]RecName: Full=UDP-glucuronosyltransferase 1-6; Short=UDPGT 1-6; Short=UGT1*6; Short=UGT1-06; Short=UGT1.6; EC=2.4.1.17; AltName: Full=Phenol-metabolizing UDP-glucuronosyltransferase; AltName: Full=UDP-glucuronosyltransferase 1-F; Short=UGT-1F; Short=UGT1F; AltName: Full=UDP-glucuronosyltransferase 1A6; Flags: Precursor;+++[B5MCT4_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[C9JMY5_HUMAN|Unreviewed]SubName: Full=UDP-glucuronosyltransferase 1-6 {ECO:0000313|Ensembl:ENSP00000389637}; Flags: Fragment;+++[H7C5F8_HUMAN|Unreviewed]SubName: Full=UDP-glucuronosyltransferase 1-6 {ECO:0000313|Ensembl:ENSP00000419780}; Flags: Fragment;+++[Q5DSZ8_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[Q5DT01_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};+++[Q8WUQ4_HUMAN|Unreviewed]RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059}; EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};"]
[54625,"'PARP14'",322,159.14,172,217.713333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0070403///NAD+ binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0070212///protein poly-ADP-ribosylation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0006471///protein ADP-ribosylation+++GO:1902216///positive regulation of interleukin-4-mediated signaling pathway+++GO:0002376///immune system process+++GO:0010629///negative regulation of gene expression+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0045087///innate immune response+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein","poly(ADP-ribose) polymerase family member 14","[PAR14_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 14; Short=PARP-14; EC=2.4.2.30 {ECO:0000255|PROSITE-ProRule:PRU00397, ECO:0000269|PubMed:16061477, ECO:0000269|PubMed:27796300}; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 8; Short=ARTD8; AltName: Full=B aggressive lymphoma protein 2;+++[D3DN94_HUMAN|Unreviewed]SubName: Full=Poly (ADP-ribose) polymerase family, member 14, isoform CRA_a {ECO:0000313|EMBL:EAW79469.1};+++[H7C4Y3_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 14 {ECO:0000313|Ensembl:ENSP00000418535}; Flags: Fragment;+++[H7C5R8_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 14 {ECO:0000313|Ensembl:ENSP00000420649}; Flags: Fragment;+++[Q8N546_HUMAN|Unreviewed]SubName: Full=PARP14 protein {ECO:0000313|EMBL:AAH32804.1}; Flags: Fragment;"]
[54675,"'CRLS1'",303,319,270,297.333333333333,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways",null,null,"R02030///CDP-diacylglycerol:phosphatidylglycerol 3-phosphatidyltransferase   Phosphatidylglycerol + CDP-diacylglycerol <=> Cardiolipin + CMP","GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0016740///transferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0008444///CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity+++GO:0008808///cardiolipin synthase activity+++GO:0043337///CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity+++GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0032049///cardiolipin biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0046474///glycerophospholipid biosynthetic process+++GO:0097068///response to thyroxine+++GO:1905711///response to phosphatidylethanolamine","cardiolipin synthase 1","[CRLS1_HUMAN|Reviewed]RecName: Full=Cardiolipin synthase (CMP-forming); Short=CLS; EC=2.7.8.41 {ECO:0000269|PubMed:16678169}; AltName: Full=Protein GCD10 homolog;+++[Q6NTG3_HUMAN|Unreviewed]SubName: Full=CRLS1 protein {ECO:0000313|EMBL:AAH69010.1}; SubName: Full=Cardiolipin synthase (CMP-forming) {ECO:0000313|Ensembl:ENSP00000416770}; SubName: Full=Chromosome 20 open reading frame 155, isoform CRA_b {ECO:0000313|EMBL:EAX10400.1};"]
[54732,"'TMED9'",7005,7554,6839,7132.66666666667,{"$nulls":4},"GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0030140///trans-Golgi network transport vesicle+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005794///Golgi apparatus+++GO:0030133///transport vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle","GO:0019905///syntaxin binding+++GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0034498///early endosome to Golgi transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048205///COPI coating of Golgi vesicle+++GO:0015031///protein transport+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007030///Golgi organization+++GO:0010638///positive regulation of organelle organization","transmembrane p24 trafficking protein 9","[TMED9_HUMAN|Reviewed]RecName: Full=Transmembrane emp24 domain-containing protein 9; AltName: Full=GMP25; AltName: Full=Glycoprotein 25L2; AltName: Full=p24 family protein alpha-2; Short=p24alpha2; AltName: Full=p25; Flags: Precursor;+++[A0A024R7M0_HUMAN|Unreviewed]SubName: Full=Transmembrane emp24 protein transport domain containing 9, isoform CRA_a {ECO:0000313|EMBL:EAW84968.1};"]
[54757,"'FAM20A'",115,173,95,127.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00615///Amelogenesis imperfecta",null,null,"GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005623///cell+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0043539///protein serine/threonine kinase activator activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0070166///enamel mineralization+++GO:0006468///protein phosphorylation+++GO:0055074///calcium ion homeostasis+++GO:0044691///tooth eruption+++GO:0001934///positive regulation of protein phosphorylation+++GO:0009617///response to bacterium+++GO:0031214///biomineral tissue development","FAM20A, golgi associated secretory pathway pseudokinase","[FA20A_HUMAN|Reviewed]RecName: Full=Pseudokinase FAM20A {ECO:0000305}; Flags: Precursor;+++[B7Z4Y3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57131, highly similar to Protein FAM20A {ECO:0000313|EMBL:BAH12719.1};+++[K7EIV7_HUMAN|Unreviewed]SubName: Full=Pseudokinase FAM20A {ECO:0000313|Ensembl:ENSP00000464910}; Flags: Fragment;+++[K7EQL5_HUMAN|Unreviewed]SubName: Full=Pseudokinase FAM20A {ECO:0000313|Ensembl:ENSP00000467884}; Flags: Fragment;+++[L8B8N7_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 20, member A {ECO:0000313|EMBL:BAM78535.1};+++[Q71MG5_HUMAN|Unreviewed]SubName: Full=Pseudokinase FAM20A {ECO:0000313|Ensembl:ENSP00000481085};+++[Q8IYA5_HUMAN|Unreviewed]SubName: Full=FAM20A protein {ECO:0000313|EMBL:AAH36222.1};"]
[54790,"'TET2'",430,241,302,324.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0051213///dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0008198///ferrous iron binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0005506///iron ion binding+++GO:0070579///methylcytosine dioxygenase activity+++GO:0046872///metal ion binding","GO:0055114///oxidation-reduction process+++GO:0006493///protein O-linked glycosylation+++GO:0030099///myeloid cell differentiation+++GO:0014070///response to organic cyclic compound+++GO:0080111///DNA demethylation+++GO:0080182///histone H3-K4 trimethylation+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006211///5-methylcytosine catabolic process","tet methylcytosine dioxygenase 2","[TET2_HUMAN|Reviewed]RecName: Full=Methylcytosine dioxygenase TET2; EC=1.14.11.n2 {ECO:0000269|PubMed:24315485};+++[A0A024RDF7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX06178.1};+++[A0A158SIU0_HUMAN|Unreviewed]SubName: Full=Tet oncogene family member 2 {ECO:0000313|EMBL:CAX30492.1};+++[A7E237_HUMAN|Unreviewed]SubName: Full=TET2 protein {ECO:0000313|EMBL:AAI50181.1};+++[D6RE87_HUMAN|Unreviewed]SubName: Full=Methylcytosine dioxygenase TET2 {ECO:0000313|Ensembl:ENSP00000426885}; Flags: Fragment;+++[E7EPB1_HUMAN|Unreviewed]SubName: Full=Methylcytosine dioxygenase TET2 {ECO:0000313|Ensembl:ENSP00000391448};+++[E7EQS8_HUMAN|Unreviewed]SubName: Full=Methylcytosine dioxygenase TET2 {ECO:0000313|Ensembl:ENSP00000425443};+++[L8E8T1_HUMAN|Unreviewed]SubName: Full=Alternative protein TET2 {ECO:0000313|EMBL:CCQ43559.1};"]
[54806,"'AHI1'",192,118,167,159,null,"H00530///Joubert syndrome",null,null,"GO:0005814///centriole+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0005912///adherens junction+++GO:0005911///cell-cell junction+++GO:0005929///cilium+++GO:0097730///non-motile cilium+++GO:0005737///cytoplasm+++GO:0036064///ciliary basal body+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0036038///MKS complex","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0065001///specification of axis polarity+++GO:0030902///hindbrain development+++GO:0071599///otic vesicle development+++GO:0007275///multicellular organism development+++GO:0035844///cloaca development+++GO:0030862///positive regulation of polarized epithelial cell differentiation+++GO:0030030///cell projection organization+++GO:0010842///retina layer formation+++GO:0050795///regulation of behavior+++GO:0043066///negative regulation of apoptotic process+++GO:0002092///positive regulation of receptor internalization+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0060271///cilium assembly+++GO:0070986///left/right axis specification+++GO:0001947///heart looping+++GO:0039023///pronephric duct morphogenesis+++GO:0039008///pronephric nephron tubule morphogenesis+++GO:0030154///cell differentiation+++GO:0070121///Kupffer's vesicle development+++GO:0007417///central nervous system development+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0001738///morphogenesis of a polarized epithelium+++GO:0034613///cellular protein localization+++GO:0016192///vesicle-mediated transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035845///photoreceptor cell outer segment organization","Abelson helper integration site 1","[AHI1_HUMAN|Reviewed]RecName: Full=Jouberin; AltName: Full=Abelson helper integration site 1 protein homolog; Short=AHI-1;+++[A2NYE6_HUMAN|Unreviewed]SubName: Full=ORF1 protein {ECO:0000313|EMBL:CAA63697.1};+++[E9PI51_HUMAN|Unreviewed]SubName: Full=Jouberin {ECO:0000313|Ensembl:ENSP00000436516};+++[E9PML3_HUMAN|Unreviewed]SubName: Full=Jouberin {ECO:0000313|Ensembl:ENSP00000433063}; Flags: Fragment;+++[H0Y343_HUMAN|Unreviewed]SubName: Full=Jouberin {ECO:0000313|Ensembl:ENSP00000356773}; Flags: Fragment;+++[H0YDL1_HUMAN|Unreviewed]SubName: Full=Jouberin {ECO:0000313|Ensembl:ENSP00000433864}; Flags: Fragment;+++[H0YE01_HUMAN|Unreviewed]SubName: Full=Jouberin {ECO:0000313|Ensembl:ENSP00000434697}; Flags: Fragment;+++[H0YEF1_HUMAN|Unreviewed]SubName: Full=Jouberin {ECO:0000313|Ensembl:ENSP00000435710}; Flags: Fragment;+++[Q8NER0_HUMAN|Unreviewed]SubName: Full=Ahi-1 isoform I {ECO:0000313|EMBL:AAM94177.1}; Flags: Fragment;+++[Q9NQN3_HUMAN|Unreviewed]SubName: Full=Jouberin {ECO:0000313|Ensembl:ENSP00000433017};"]
[54823,"'SWT1'",63,31,31,41.6666666666667,"05164///Influenza A+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus",null,"GO:0006351///transcription, DNA-templated","SWT1, RNA endoribonuclease homolog","[SWT1_HUMAN|Reviewed]RecName: Full=Transcriptional protein SWT1;+++[B3KXU9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46095 fis, clone TESTI2018867 {ECO:0000313|EMBL:BAG54611.1};+++[Q5TC96_HUMAN|Unreviewed]SubName: Full=Transcriptional protein SWT1 {ECO:0000313|Ensembl:ENSP00000401413}; Flags: Fragment;"]
[54852,"'PAQR5'",32,20,32,28,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0038023///signaling receptor activity+++GO:0005515///protein binding+++GO:0005496///steroid binding+++GO:0008289///lipid binding","GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0048477///oogenesis","progestin and adipoQ receptor family member 5","[PAQR5_HUMAN|Reviewed]RecName: Full=Membrane progestin receptor gamma {ECO:0000303|PubMed:23763432}; Short=mPR gamma {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone P4 receptor gamma {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone receptor gamma {ECO:0000303|PubMed:23763432}; AltName: Full=Progesterone and adipoQ receptor family member 5; AltName: Full=Progestin and adipoQ receptor family member 5 {ECO:0000303|PubMed:16044242}; AltName: Full=Progestin and adipoQ receptor family member V;+++[A0A024R607_HUMAN|Unreviewed]SubName: Full=Progestin and adipoQ receptor family member V, isoform CRA_a {ECO:0000313|EMBL:EAW77839.1};+++[H0YL06_HUMAN|Unreviewed]SubName: Full=Membrane progestin receptor gamma {ECO:0000313|Ensembl:ENSP00000453009}; Flags: Fragment;+++[L8E9R0_HUMAN|Unreviewed]SubName: Full=Alternative protein PAQR5 {ECO:0000313|EMBL:CCQ43083.1};"]
[54861,"'SNRK'",287,221,234,247.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0030099///myeloid cell differentiation","SNF related kinase","[SNRK_HUMAN|Reviewed]RecName: Full=SNF-related serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=SNF1-related kinase;+++[A0A024R2Y6_HUMAN|Unreviewed]SubName: Full=SNF related kinase, isoform CRA_a {ECO:0000313|EMBL:EAW64694.1};+++[A8K5P5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77864, highly similar to Homo sapiens HSNFRK (HSNFRK) mRNA {ECO:0000313|EMBL:BAF84049.1};+++[B4DHM9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59517, highly similar to SNF-related serine/threonine-protein kinase {ECO:0000313|EMBL:BAG58191.1};+++[E7EUC4_HUMAN|Unreviewed]SubName: Full=SNF-related serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000409516};"]
[54884,"'RETSAT'",1345,1301,1229,1291.66666666667,"00830///Retinol metabolism",null,null,"R07163///all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductas   all-trans-13,14-Dihydroretinol + Acceptor <=> Retinol + Reduced acceptor","GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005640///nuclear outer membrane+++GO:0031965///nuclear membrane","GO:0051786///all-trans-retinol 13,14-reductase activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0042572///retinol metabolic process","retinol saturase","[RETST_HUMAN|Reviewed]RecName: Full=All-trans-retinol 13,14-reductase; EC=1.3.99.23; AltName: Full=All-trans-13,14-dihydroretinol saturase; Short=RetSat; AltName: Full=PPAR-alpha-regulated and starvation-induced gene protein; Flags: Precursor;+++[H0YGU3_HUMAN|Unreviewed]SubName: Full=All-trans-retinol 13,14-reductase {ECO:0000313|Ensembl:ENSP00000444814}; Flags: Fragment;+++[H7BZ16_HUMAN|Unreviewed]SubName: Full=All-trans-retinol 13,14-reductase {ECO:0000313|Ensembl:ENSP00000387196}; Flags: Fragment;+++[H7BZ81_HUMAN|Unreviewed]SubName: Full=All-trans-retinol 13,14-reductase {ECO:0000313|Ensembl:ENSP00000388202}; Flags: Fragment;+++[H7C3J0_HUMAN|Unreviewed]SubName: Full=All-trans-retinol 13,14-reductase {ECO:0000313|Ensembl:ENSP00000412166}; Flags: Fragment;+++[I0EZ74_HUMAN|Unreviewed]SubName: Full=Retinol saturase {ECO:0000313|EMBL:AFI24910.1}; Flags: Fragment;"]
[54894,"'RNF43'",6,5,6,5.66666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005635///nuclear envelope","GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0005109///frizzled binding+++GO:0061630///ubiquitin protein ligase activity","GO:0016055///Wnt signaling pathway+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0038018///Wnt receptor catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0072089///stem cell proliferation+++GO:0030178///negative regulation of Wnt signaling pathway","ring finger protein 43","[RNF43_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF43; EC=2.3.2.27; AltName: Full=RING finger protein 43; AltName: Full=RING-type E3 ubiquitin transferase RNF43 {ECO:0000305}; Flags: Precursor;+++[J3KSE3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF43 {ECO:0000313|Ensembl:ENSP00000462447};"]
[54902,"'TTC19'",367,305,408,360,"05202///Transcriptional misregulation in cancer+++01522///Endocrine resistance+++04919///Thyroid hormone signaling pathway","H02086///Mitochondrial complex III deficiency",null,null,"GO:0016020///membrane+++GO:0070469///respiratory chain+++GO:0005813///centrosome+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0030496///midbody","GO:0005515///protein binding","GO:0034551///mitochondrial respiratory chain complex III assembly+++GO:0007049///cell cycle+++GO:0000281///mitotic cytokinesis+++GO:0051301///cell division+++GO:0055114///oxidation-reduction process","tetratricopeptide repeat domain 19","[TTC19_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 19, mitochondrial; Short=TPR repeat protein 19; Flags: Precursor;+++[A0A024RD83_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat domain 19, isoform CRA_a {ECO:0000313|EMBL:EAX04491.1};+++[K7EJA1_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 19, mitochondrial {ECO:0000313|Ensembl:ENSP00000465082}; Flags: Fragment;+++[K7EKH7_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 19, mitochondrial {ECO:0000313|Ensembl:ENSP00000465627}; Flags: Fragment;+++[K7EKS0_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 19, mitochondrial {ECO:0000313|Ensembl:ENSP00000465754}; Flags: Fragment;+++[K7ELX2_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 19, mitochondrial {ECO:0000313|Ensembl:ENSP00000466261}; Flags: Fragment;+++[K7ERR1_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 19, mitochondrial {ECO:0000313|Ensembl:ENSP00000468372}; Flags: Fragment;"]
[54930,"'HAUS4'",111,139,128,126,{"$nulls":4},"GO:0005819///spindle+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0070652///HAUS complex+++GO:0005813///centrosome+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0000086///G2/M transition of mitotic cell cycle","HAUS augmin like complex subunit 4","[HAUS4_HUMAN|Reviewed]RecName: Full=HAUS augmin-like complex subunit 4;+++[G3V2I5_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450680}; Flags: Fragment;+++[G3V4X7_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452058}; Flags: Fragment;+++[G3V541_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452165}; Flags: Fragment;+++[G3V5A5_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452261}; Flags: Fragment;+++[G3V5Z2_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452595}; Flags: Fragment;+++[H0YIZ6_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450542}; Flags: Fragment;+++[H0YJ09_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450612}; Flags: Fragment;"]
[5494,"'PPM1A'",423,329,357,369.666666666667,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0030145///manganese ion binding+++GO:0000287///magnesium ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0003824///catalytic activity+++GO:0033192///calmodulin-dependent protein phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0046872///metal ion binding+++GO:0070412///R-SMAD binding+++GO:0043169///cation binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0016311///dephosphorylation+++GO:0006470///protein dephosphorylation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0007050///cell cycle arrest+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0010991///negative regulation of SMAD protein complex assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0046827///positive regulation of protein export from nucleus+++GO:0006499///N-terminal protein myristoylation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling","protein phosphatase, Mg2+/Mn2+ dependent 1A","[PPM1A_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1A; EC=3.1.3.16; AltName: Full=Protein phosphatase 2C isoform alpha; Short=PP2C-alpha; AltName: Full=Protein phosphatase IA;+++[A0A024R6A5_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1A (Formerly 2C), magnesium-dependent, alpha isoform, isoform CRA_a {ECO:0000313|EMBL:EAW80775.1};+++[B2R8E4_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93859, highly similar to Homo sapiens protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform (PPM1A), mRNA {ECO:0000313|EMBL:BAG36141.1};+++[B5BUD5_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1A isoform 1 {ECO:0000313|EMBL:BAG70185.1}; Flags: Fragment;+++[E9PJN3_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1A {ECO:0000313|Ensembl:ENSP00000435575}; Flags: Fragment;+++[E9PKB5_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1A {ECO:0000313|Ensembl:ENSP00000435398}; Flags: Fragment;+++[E9PL75_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1A {ECO:0000313|Ensembl:ENSP00000431453}; Flags: Fragment;+++[E9PNE1_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1A {ECO:0000313|Ensembl:ENSP00000437200};+++[E9PP44_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1A {ECO:0000313|Ensembl:ENSP00000436445};+++[L8EAT3_HUMAN|Unreviewed]SubName: Full=Alternative protein PPM1A {ECO:0000313|EMBL:CCQ43911.1};"]
[54962,"'TIPIN'",46.16,38.56,44,42.9066666666667,"03018///RNA degradation",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0031298///replication fork protection complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0044770///cell cycle phase transition+++GO:0043111///replication fork arrest+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0033262///regulation of nuclear cell cycle DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008284///positive regulation of cell proliferation+++GO:0031573///intra-S DNA damage checkpoint+++GO:0000077///DNA damage checkpoint+++GO:0048478///replication fork protection+++GO:0000076///DNA replication checkpoint+++GO:0009411///response to UV","TIMELESS interacting protein","[TIPIN_HUMAN|Reviewed]RecName: Full=TIMELESS-interacting protein;+++[B4DRF3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53020, highly similar to Homo sapiens timeless-interacting protein, mRNA {ECO:0000313|EMBL:BAG61265.1};+++[H3BQ83_HUMAN|Unreviewed]SubName: Full=TIMELESS-interacting protein {ECO:0000313|Ensembl:ENSP00000455656};+++[H3BTH1_HUMAN|Unreviewed]SubName: Full=TIMELESS-interacting protein {ECO:0000313|Ensembl:ENSP00000457172}; Flags: Fragment;+++[H3BU04_HUMAN|Unreviewed]SubName: Full=TIMELESS-interacting protein {ECO:0000313|Ensembl:ENSP00000457406}; Flags: Fragment;+++[H3BVG9_HUMAN|Unreviewed]SubName: Full=TIMELESS-interacting protein {ECO:0000313|Ensembl:ENSP00000458117}; Flags: Fragment;"]
[54974,"'THG1L'",97,98,88,94.3333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0000049///tRNA binding+++GO:0016779///nucleotidyltransferase activity+++GO:0000166///nucleotide binding+++GO:0008193///tRNA guanylyltransferase activity+++GO:0046872///metal ion binding+++GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0000287///magnesium ion binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0008033///tRNA processing+++GO:0006400///tRNA modification+++GO:0051289///protein homotetramerization+++GO:0099116///tRNA 5'-end processing","tRNA-histidine guanylyltransferase 1 like","[THG1_HUMAN|Reviewed]RecName: Full=Probable tRNA(His) guanylyltransferase; EC=2.7.7.79 {ECO:0000269|PubMed:21059936}; AltName: Full=Interphase cytoplasmic foci protein 45; AltName: Full=tRNA-histidine guanylyltransferase;+++[B4E366_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57781, highly similar to Homo sapiens tRNA-histidine guanylyltransferase 1-like (THG1L), mRNA {ECO:0000313|EMBL:BAG65378.1};+++[E5RIQ8_HUMAN|Unreviewed]SubName: Full=Probable tRNA(His) guanylyltransferase {ECO:0000313|Ensembl:ENSP00000428387};+++[H0YC78_HUMAN|Unreviewed]SubName: Full=Probable tRNA(His) guanylyltransferase {ECO:0000313|Ensembl:ENSP00000431090}; Flags: Fragment;+++[Q9H8R6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ13293 fis, clone OVARC1001188 {ECO:0000313|EMBL:BAB14540.1};"]
[54997,"'TESC'",18,15,8,13.6666666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0042995///cell projection+++GO:0030027///lamellipodium+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity+++GO:0004860///protein kinase inhibitor activity+++GO:0000287///magnesium ion binding+++GO:0019212///phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0030854///positive regulation of granulocyte differentiation+++GO:0032417///positive regulation of sodium:proton antiporter activity+++GO:0008285///negative regulation of cell proliferation+++GO:0051604///protein maturation+++GO:0030154///cell differentiation+++GO:0006469///negative regulation of protein kinase activity+++GO:0072659///protein localization to plasma membrane+++GO:0010628///positive regulation of gene expression+++GO:0015031///protein transport+++GO:0050821///protein stabilization+++GO:0043086///negative regulation of catalytic activity+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0071300///cellular response to retinoic acid","tescalcin","[CHP3_HUMAN|Reviewed]RecName: Full=Calcineurin B homologous protein 3; AltName: Full=Tescalcin; Short=TSC;+++[E9PQ58_HUMAN|Unreviewed]SubName: Full=Calcineurin B homologous protein 3 {ECO:0000313|Ensembl:ENSP00000432608};+++[H0YIX4_HUMAN|Unreviewed]SubName: Full=Calcineurin B homologous protein 3 {ECO:0000313|Ensembl:ENSP00000450386}; Flags: Fragment;"]
[55008,"'HERC6'",74,40,34,49.3333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0000209///protein polyubiquitination+++GO:0009617///response to bacterium+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0016567///protein ubiquitination","HECT and RLD domain containing E3 ubiquitin protein ligase family member 6","[HERC6_HUMAN|Reviewed]RecName: Full=Probable E3 ubiquitin-protein ligase HERC6; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 6; AltName: Full=HECT-type E3 ubiquitin transferase HERC6;+++[A0A0B4J1R3_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase HERC6 {ECO:0000313|Ensembl:ENSP00000273960};+++[D6RCT4_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase HERC6 {ECO:0000313|Ensembl:ENSP00000425504};+++[H0Y9U0_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase HERC6 {ECO:0000313|Ensembl:ENSP00000425060}; Flags: Fragment;"]
[55031,"'USP47'",576,494,499,523,{"$nulls":4},"GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0019005///SCF ubiquitin ligase complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0003712///transcription coregulator activity+++GO:0016787///hydrolase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0071987///WD40-repeat domain binding+++GO:0101005///ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0008234///cysteine-type peptidase activity","GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0031647///regulation of protein stability+++GO:0006508///proteolysis+++GO:0034644///cellular response to UV+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006284///base-excision repair+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0016579///protein deubiquitination+++GO:0006281///DNA repair+++GO:0030307///positive regulation of cell growth+++GO:0042493///response to drug","ubiquitin specific peptidase 47","[UBP47_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 47; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 47; AltName: Full=Ubiquitin thioesterase 47; AltName: Full=Ubiquitin-specific-processing protease 47;+++[A0PJ80_HUMAN|Unreviewed]SubName: Full=USP47 protein {ECO:0000313|EMBL:AAH17795.1}; Flags: Fragment;+++[Q68D97_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686C13257 {ECO:0000313|EMBL:CAH18323.1};"]
[55051,"'NRDE2'",150,145,131,142,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0031048///chromatin silencing by small RNA+++GO:0016246///RNA interference+++GO:0008150///biological_process","NRDE-2, necessary for RNA interference, domain containing","[NRDE2_HUMAN|Reviewed]RecName: Full=Protein NRDE2 homolog;+++[A0A024R6L8_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 102, isoform CRA_c {ECO:0000313|EMBL:EAW81425.1};+++[G3V338_HUMAN|Unreviewed]SubName: Full=Protein NRDE2 homolog {ECO:0000313|Ensembl:ENSP00000451025};+++[H0YJT0_HUMAN|Unreviewed]SubName: Full=Protein NRDE2 homolog {ECO:0000313|Ensembl:ENSP00000452071}; Flags: Fragment;+++[H0YJT6_HUMAN|Unreviewed]SubName: Full=Protein NRDE2 homolog {ECO:0000313|Ensembl:ENSP00000452107}; Flags: Fragment;+++[Q0VFW7_HUMAN|Unreviewed]SubName: Full=C14orf102 protein {ECO:0000313|EMBL:AAI18674.1}; SubName: Full=Chromosome 14 open reading frame 102, isoform CRA_b {ECO:0000313|EMBL:EAW81423.1};"]
[55074,"'OXR1'",185,123,118,142,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0016491///oxidoreductase activity","GO:0043524///negative regulation of neuron apoptotic process+++GO:1900408///negative regulation of cellular response to oxidative stress+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0051402///neuron apoptotic process+++GO:0071447///cellular response to hydroperoxide+++GO:0055114///oxidation-reduction process+++GO:1902083///negative regulation of peptidyl-cysteine S-nitrosylation+++GO:0006979///response to oxidative stress+++GO:0007628///adult walking behavior","oxidation resistance 1","[OXR1_HUMAN|Reviewed]RecName: Full=Oxidation resistance protein 1;+++[C9JY63_HUMAN|Unreviewed]SubName: Full=Oxidation resistance protein 1 {ECO:0000313|Ensembl:ENSP00000387886};+++[E5RFD1_HUMAN|Unreviewed]SubName: Full=Oxidation resistance protein 1 {ECO:0000313|Ensembl:ENSP00000414992};+++[E5RII8_HUMAN|Unreviewed]SubName: Full=Oxidation resistance protein 1 {ECO:0000313|Ensembl:ENSP00000429438}; Flags: Fragment;+++[E9PLW2_HUMAN|Unreviewed]SubName: Full=Oxidation resistance protein 1 {ECO:0000313|Ensembl:ENSP00000435104};+++[H0YC07_HUMAN|Unreviewed]SubName: Full=Oxidation resistance protein 1 {ECO:0000313|Ensembl:ENSP00000430701}; Flags: Fragment;+++[Q05CY8_HUMAN|Unreviewed]SubName: Full=OXR1 protein {ECO:0000313|EMBL:AAH19691.1}; Flags: Fragment;"]
[55093,"'WDYHV1'",28,27,59.22,38.0733333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,null,"R11560///protein N-terminal glutamine amidohydrolase   L-Glutaminyl-peptide + H2O <=> L-Glutamyl-protein + Ammonia","GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0070773///protein-N-terminal glutamine amidohydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","GO:0006464///cellular protein modification process","WDYHV motif containing 1","[NTAQ1_HUMAN|Reviewed]RecName: Full=Protein N-terminal glutamine amidohydrolase; EC=3.5.1.122 {ECO:0000250|UniProtKB:Q80WB5}; AltName: Full=Protein NH2-terminal glutamine deamidase; Short=N-terminal Gln amidase; Short=Nt(Q)-amidase; AltName: Full=WDYHV motif-containing protein 1;+++[A0A024R9I8_HUMAN|Unreviewed]SubName: Full=Chromosome 8 open reading frame 32, isoform CRA_a {ECO:0000313|EMBL:EAW92039.1};+++[E5RHC2_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000428615};+++[E5RIY9_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000429258};+++[E9PRB7_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000434252}; Flags: Fragment;+++[H0YBV4_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000430390}; Flags: Fragment;"]
[55112,"'WDR60'",528,496,538,520.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis+++04668///TNF signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04144///Endocytosis","H01901///Barrett's esophagus+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H01232///Syndromic multisystem autoimmune disease",null,null,"GO:0042995///cell projection+++GO:0005868///cytoplasmic dynein complex+++GO:0097542///ciliary tip+++GO:0000242///pericentriolar material+++GO:0030286///dynein complex+++GO:0005615///extracellular space+++GO:0097546///ciliary base+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0031021///interphase microtubule organizing center+++GO:0005929///cilium","GO:0045504///dynein heavy chain binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0045503///dynein light chain binding+++GO:0005515///protein binding","GO:0048704///embryonic skeletal system morphogenesis+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0060271///cilium assembly+++GO:0007018///microtubule-based movement+++GO:0030030///cell projection organization","WD repeat domain 60","[WDR60_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 60;+++[A0A140VK66_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 66 {ECO:0000313|EMBL:AEE61203.1};+++[H7BYQ2_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 60 {ECO:0000313|Ensembl:ENSP00000380330}; Flags: Fragment;+++[H7C022_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 60 {ECO:0000313|Ensembl:ENSP00000392608}; Flags: Fragment;+++[H7C1E8_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 60 {ECO:0000313|Ensembl:ENSP00000399971}; Flags: Fragment;"]
[55132,"'LARP1B'",270,195,197,220.666666666667,"04310///Wnt signaling pathway+++04380///Osteoclast differentiation+++04137///Mitophagy - animal+++05166///HTLV-I infection+++04657///IL-17 signaling pathway+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0008284///positive regulation of cell proliferation+++GO:0006935///chemotaxis+++GO:0051591///response to cAMP+++GO:0043065///positive regulation of apoptotic process+++GO:0045787///positive regulation of cell cycle+++GO:0007296///vitellogenesis+++GO:0007565///female pregnancy+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051412///response to corticosterone+++GO:0060674///placenta blood vessel development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0042542///response to hydrogen peroxide+++GO:0007612///learning+++GO:0006968///cellular defense response+++GO:0009615///response to virus+++GO:0001701///in utero embryonic development+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0009629///response to gravity+++GO:0006366///transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0032570///response to progesterone+++GO:0009612///response to mechanical stimulus+++GO:0034097///response to cytokine+++GO:0031668///cellular response to extracellular stimulus","La ribonucleoprotein domain family member 1B","[LAR1B_HUMAN|Reviewed]RecName: Full=La-related protein 1B; AltName: Full=La ribonucleoprotein domain family member 1B; AltName: Full=La ribonucleoprotein domain family member 2; AltName: Full=La-related protein 2;+++[D6R9W6_HUMAN|Unreviewed]SubName: Full=La-related protein 1B {ECO:0000313|Ensembl:ENSP00000422850};+++[D6RJB0_HUMAN|Unreviewed]SubName: Full=La-related protein 1B {ECO:0000313|Ensembl:ENSP00000427281}; Flags: Fragment;+++[G3V0E9_HUMAN|Unreviewed]SubName: Full=La ribonucleoprotein domain family, member 2, isoform CRA_d {ECO:0000313|EMBL:EAX05187.1}; SubName: Full=La-related protein 1B {ECO:0000313|Ensembl:ENSP00000390395};+++[H0Y9B4_HUMAN|Unreviewed]SubName: Full=La-related protein 1B {ECO:0000313|Ensembl:ENSP00000423686}; Flags: Fragment;+++[H0Y9K3_HUMAN|Unreviewed]SubName: Full=La-related protein 1B {ECO:0000313|Ensembl:ENSP00000424383}; Flags: Fragment;"]
[5515,"'PPP2CA'",1461,1307,1387,1385,"05142///Chagas disease (American trypanosomiasis)+++04138///Autophagy - yeast+++04152///AMPK signaling pathway+++04730///Long-term depression+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04013///MAPK signaling pathway - fly+++05165///Human papillomavirus infection+++04113///Meiosis - yeast+++04140///Autophagy - animal+++04728///Dopaminergic synapse+++04151///PI3K-Akt signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04111///Cell cycle - yeast+++04136///Autophagy - other+++03015///mRNA surveillance pathway+++04350///TGF-beta signaling pathway+++05160///Hepatitis C+++04530///Tight junction+++04114///Oocyte meiosis+++04071///Sphingolipid signaling pathway",{"$nulls":3},"GO:0000922///spindle pole+++GO:0070062///extracellular exosome+++GO:0015630///microtubule cytoskeleton+++GO:0045202///synapse+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0000159///protein phosphatase type 2A complex+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0000775///chromosome, centromeric region","GO:0016787///hydrolase activity+++GO:0048156///tau protein binding+++GO:0050811///GABA receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0008022///protein C-terminus binding","GO:0040008///regulation of growth+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010288///response to lead ion+++GO:0019932///second-messenger-mediated signaling+++GO:0045595///regulation of cell differentiation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0070262///peptidyl-serine dephosphorylation+++GO:0006275///regulation of DNA replication+++GO:0006915///apoptotic process+++GO:0006672///ceramide metabolic process+++GO:0010033///response to organic substance+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0001932///regulation of protein phosphorylation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0030155///regulation of cell adhesion+++GO:0030308///negative regulation of cell growth+++GO:1904528///positive regulation of microtubule binding+++GO:0051321///meiotic cell cycle+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:1904526///regulation of microtubule binding+++GO:0008380///RNA splicing+++GO:0007498///mesoderm development+++GO:0006470///protein dephosphorylation+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0030111///regulation of Wnt signaling pathway+++GO:0000188///inactivation of MAPK activity","protein phosphatase 2 catalytic subunit alpha","[PP2AA_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; Short=PP2A-alpha; EC=3.1.3.16; AltName: Full=Replication protein C; Short=RP-C;+++[B3KUN1_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[E5RHP4_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[E7ESG8_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[Q6I9T8_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};"]
[55168,"'MRPS18A'",557,685,732,658,"03010///Ribosome","H00564///Primary ciliary dyskinesia","M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005762///mitochondrial large ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0070181///small ribosomal subunit rRNA binding","GO:0070126///mitochondrial translational termination+++GO:0006412///translation+++GO:0070125///mitochondrial translational elongation+++GO:0032543///mitochondrial translation","mitochondrial ribosomal protein S18A","[RT18A_HUMAN|Reviewed]RecName: Full=39S ribosomal protein S18a, mitochondrial; Short=MRP-S18-a; Short=Mrps18a; Short=S18mt-a; AltName: Full=39S ribosomal protein S18-3, mitochondrial; Short=MRP-S18-3; AltName: Full=Mitochondrial large ribosomal subunit protein bS18a {ECO:0000303|PubMed:25278503}; AltName: Full=Mitochondrial large ribosomal subunit protein mL66 {ECO:0000303|PubMed:27023846}; Flags: Precursor;+++[Q5QPA5_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein S18a, mitochondrial {ECO:0000313|Ensembl:ENSP00000398679}; Flags: Fragment;"]
[55183,"'RIF1'",309,193,205,235.666666666667,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0001939///female pronucleus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0051233///spindle midzone+++GO:0035861///site of double-strand break+++GO:0016604///nuclear body+++GO:0005886///plasma membrane+++GO:0000781///chromosome, telomeric region+++GO:0005654///nucleoplasm+++GO:0001940///male pronucleus+++GO:0000793///condensed chromosome+++GO:0000790///nuclear chromatin+++GO:0031965///nuclear membrane",null,"GO:0007049///cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:0006348///chromatin silencing at telomere+++GO:0019827///stem cell population maintenance+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining+++GO:0045830///positive regulation of isotype switching+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0000723///telomere maintenance+++GO:0043247///telomere maintenance in response to DNA damage+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:0006974///cellular response to DNA damage stimulus","replication timing regulatory factor 1","[RIF1_HUMAN|Reviewed]RecName: Full=Telomere-associated protein RIF1 {ECO:0000305}; AltName: Full=Rap1-interacting factor 1 homolog {ECO:0000305|PubMed:15342490};"]
[55199,"'FAM86C1'",353.63,445.38,442.51,413.84,{"$nulls":4},"GO:0032991///protein-containing complex","GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0005515///protein binding","GO:0032259///methylation","family with sequence similarity 86 member C1","[FA86C_HUMAN|Reviewed]RecName: Full=Protein FAM86C1; EC=2.1.1.- {ECO:0000250|UniProtKB:P47163}; AltName: Full=Protein FAM86C;+++[B4DDJ9_HUMAN|Unreviewed]SubName: Full=Protein FAM86C1 {ECO:0000313|Ensembl:ENSP00000436598}; SubName: Full=cDNA FLJ57700, weakly similar to Protein FAM86A {ECO:0000313|EMBL:BAG56760.1};+++[D6R9N2_HUMAN|Unreviewed]SubName: Full=Protein FAM86C1 {ECO:0000313|Ensembl:ENSP00000423511};"]
[55200,"'PLEKHG6'",69,60,112,80.3333333333333,"04060///Cytokine-cytokine receptor interaction+++05168///Herpes simplex infection+++05010///Alzheimer's disease+++05165///Human papillomavirus infection+++04010///MAPK signaling pathway+++04215///Apoptosis - multiple species+++05145///Toxoplasmosis+++05166///HTLV-I infection+++05014///Amyotrophic lateral sclerosis (ALS)+++05418///Fluid shear stress and atherosclerosis+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04380///Osteoclast differentiation+++05152///Tuberculosis+++04150///mTOR signaling pathway+++05164///Influenza A+++05163///Human cytomegalovirus infection+++04931///Insulin resistance+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05160///Hepatitis C+++04064///NF-kappa B signaling pathway+++04217///Necroptosis+++04210///Apoptosis+++05142///Chagas disease (American trypanosomiasis)+++04920///Adipocytokine signaling pathway+++04071///Sphingolipid signaling pathway+++04668///TNF signaling pathway","H01490///Multiple sclerosis+++H00912///Tumor necrosis factor receptor-associated periodic syndrome (TRAPS)",null,null,"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0032154///cleavage furrow+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0000922///spindle pole+++GO:0030054///cell junction+++GO:0005819///spindle+++GO:0005902///microvillus","GO:0005515///protein binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0035023///regulation of Rho protein signal transduction","pleckstrin homology and RhoGEF domain containing G6","[PKHG6_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family G member 6; Short=PH domain-containing family G member 6; AltName: Full=Myosin-interacting guanine nucleotide exchange factor; Short=MyoGEF;+++[A0A2X0TW08_HUMAN|Unreviewed]SubName: Full=PLEKHG6 {ECO:0000313|EMBL:SPT35786.1}; Flags: Fragment;+++[D3DUR0_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain containing, family G (With RhoGef domain) member 6, isoform CRA_a {ECO:0000313|EMBL:EAW88810.1};+++[F5H731_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family G member 6 {ECO:0000313|Ensembl:ENSP00000442836};"]
[5523,"'PPP2R3A'",506,353,425,428,"04152///AMPK signaling pathway+++04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++04071///Sphingolipid signaling pathway+++04728///Dopaminergic synapse+++04261///Adrenergic signaling in cardiomyocytes+++03015///mRNA surveillance pathway",{"$nulls":3},"GO:0000159///protein phosphatase type 2A complex","GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0030674///protein binding, bridging","GO:0006470///protein dephosphorylation+++GO:0090249///regulation of cell motility involved in somitogenic axis elongation+++GO:0061053///somite development+++GO:0007525///somatic muscle development+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0045732///positive regulation of protein catabolic process+++GO:0090244///Wnt signaling pathway involved in somitogenesis+++GO:0001754///eye photoreceptor cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway","protein phosphatase 2 regulatory subunit B''alpha","[P2R3A_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha; AltName: Full=PP2A subunit B isoform PR72/PR130; AltName: Full=PP2A subunit B isoform R3 isoform; AltName: Full=PP2A subunit B isoforms B''-PR72/PR130; AltName: Full=PP2A subunit B isoforms B72/B130; AltName: Full=Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B;+++[A0JLT3_HUMAN|Unreviewed]SubName: Full=PPP2R3A protein {ECO:0000313|EMBL:AAH15034.1}; Flags: Fragment;+++[A0PJH4_HUMAN|Unreviewed]SubName: Full=PPP2R3A protein {ECO:0000313|EMBL:AAH29409.1}; Flags: Fragment;+++[H7C1M1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha {ECO:0000313|Ensembl:ENSP00000400980}; Flags: Fragment;+++[Q6P0N9_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 2 (Formerly 2A), regulatory subunit B'', alpha {ECO:0000313|EMBL:AAH65531.1};"]
[55234,"'SMU1'",391,370,349,370,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0071005///U2-type precatalytic spliceosome+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0005515///protein binding","GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing","SMU1, DNA replication regulator and spliceosomal factor","[SMU1_HUMAN|Reviewed]RecName: Full=WD40 repeat-containing protein SMU1; AltName: Full=Smu-1 suppressor of mec-8 and unc-52 protein homolog; Contains: RecName: Full=WD40 repeat-containing protein SMU1, N-terminally processed;+++[A0MNN4_HUMAN|Unreviewed]SubName: Full=CDW3/SMU1 {ECO:0000313|EMBL:ABK41103.1}; SubName: Full=Smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans), isoform CRA_a {ECO:0000313|EMBL:EAW58522.1};"]
[55249,"'YY1AP1'",1214.54,1155.64,1213.1,1194.42666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0031011///Ino80 complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0001650///fibrillar center","GO:0005515///protein binding+++GO:0003714///transcription corepressor activity","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0030183///B cell differentiation+++GO:0051726///regulation of cell cycle","YY1 associated protein 1","[YYAP1_HUMAN|Reviewed]RecName: Full=YY1-associated protein 1 {ECO:0000303|PubMed:14744866}; AltName: Full=Hepatocellular carcinoma susceptibility protein {ECO:0000303|PubMed:11710830}; AltName: Full=Hepatocellular carcinoma-associated protein 2 {ECO:0000303|PubMed:11710830};+++[A3KFK1_HUMAN|Unreviewed]SubName: Full=YY1-associated protein 1 {ECO:0000313|Ensembl:ENSP00000409203}; Flags: Fragment;+++[A3KFK2_HUMAN|Unreviewed]SubName: Full=YY1-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413240}; Flags: Fragment;+++[B0QZ55_HUMAN|Unreviewed]SubName: Full=YY1-associated protein 1 {ECO:0000313|Ensembl:ENSP00000384583};+++[B4DQQ0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59281, highly similar to YY1-associated protein 1 {ECO:0000313|EMBL:BAG61012.1};+++[B4DZQ4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59159, highly similar to YY1-associated protein 1 {ECO:0000313|EMBL:BAG64166.1};+++[F8WD62_HUMAN|Unreviewed]SubName: Full=YY1-associated protein 1 {ECO:0000313|Ensembl:ENSP00000390116};+++[I6L9C2_HUMAN|Unreviewed]SubName: Full=YY1AP1 protein {ECO:0000313|EMBL:AAH44887.1};+++[Q68CT8_HUMAN|Unreviewed]SubName: Full=YY1-associated protein 1 {ECO:0000313|Ensembl:ENSP00000354716};"]
[55270,"'NUDT15'",129,102,110,113.666666666667,{"$nulls":4},"GO:0005829///cytosol","GO:0017110///nucleoside-diphosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004551///nucleotide diphosphatase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0008413///8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity+++GO:0046872///metal ion binding+++GO:0035539///8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity","GO:0006203///dGTP catabolic process+++GO:0042262///DNA protection+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0034656///nucleobase-containing small molecule catabolic process+++GO:0006195///purine nucleotide catabolic process+++GO:0000278///mitotic cell cycle+++GO:1901292///nucleoside phosphate catabolic process+++GO:0042738///exogenous drug catabolic process","nudix hydrolase 15","[NUD15_HUMAN|Reviewed]RecName: Full=Nucleotide triphosphate diphosphatase NUDT15 {ECO:0000305}; EC=3.6.1.9 {ECO:0000269|PubMed:22556419, ECO:0000269|PubMed:26238318, ECO:0000269|PubMed:26878724}; AltName: Full=MutT homolog 2 {ECO:0000303|PubMed:19419956}; Short=MTH2 {ECO:0000303|PubMed:19419956}; AltName: Full=Nucleoside diphosphate-linked moiety X motif 15 {ECO:0000305}; Short=Nudix motif 15 {ECO:0000305}; AltName: Full=Nucleoside diphosphate-linked to another moiety X hydrolase 15 {ECO:0000303|PubMed:8810257}; Short=Nudix hydrolase 15 {ECO:0000312|HGNC:HGNC:23063};"]
[55282,"'LRRC36'",1,1,0,0.666666666666667,{"$nulls":7},"leucine rich repeat containing 36","[LRC36_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 36; AltName: Full=ROR gamma-binding protein 70;+++[B7Z4G3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50807, highly similar to Homo sapiens leucine rich repeat containing 36 (LRRC36), mRNA {ECO:0000313|EMBL:BAH12549.1};+++[H3BND7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000454794};+++[H3BNV0_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000455018};+++[H3BQI9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000455799};+++[H3BRB2_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000456164};+++[H3BRP7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000456347}; Flags: Fragment;+++[H3BS33_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000456517};+++[H3BSQ6_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000456814}; Flags: Fragment;+++[J3QRT0_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000464367}; Flags: Fragment;+++[J3QSG3_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 36 {ECO:0000313|Ensembl:ENSP00000464675}; Flags: Fragment;"]
[55304,"'SPTLC3'",2,1,3,2,"01100///Metabolic pathways+++00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway+++04138///Autophagy - yeast","H00265///Hereditary sensory and autonomic neuropathy (HSAN)","M00099///Sphingosine biosynthesis+++M00094///Ceramide biosynthesis","R01281///Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)   Palmitoyl-CoA + L-Serine <=> 3-Dehydrosphinganine + CoA + CO2","GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0017059///serine C-palmitoyltransferase complex","GO:0004758///serine C-palmitoyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0030170///pyridoxal phosphate binding+++GO:0003824///catalytic activity+++GO:0016740///transferase activity+++GO:0008483///transaminase activity","GO:0006665///sphingolipid metabolic process+++GO:0009058///biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0046520///sphingoid biosynthetic process","serine palmitoyltransferase long chain base subunit 3","[SPTC3_HUMAN|Reviewed]RecName: Full=Serine palmitoyltransferase 3; EC=2.3.1.50; AltName: Full=Long chain base biosynthesis protein 2b; Short=LCB2b; AltName: Full=Long chain base biosynthesis protein 3; Short=LCB 3; AltName: Full=Serine-palmitoyl-CoA transferase 3; Short=SPT 3;+++[B1AKS2_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 3 {ECO:0000313|Ensembl:ENSP00000389749}; SubName: Full=Serine palmitoyltransferase, long chain base subunit 2-like (Aminotransferase 2) {ECO:0000313|EMBL:CAI13234.1}; Flags: Fragment;+++[B1AKS3_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 3 {ECO:0000313|Ensembl:ENSP00000409125}; SubName: Full=Serine palmitoyltransferase, long chain base subunit 2-like (Aminotransferase 2) {ECO:0000313|EMBL:CAI13236.1}; Flags: Fragment;+++[H0Y733_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 3 {ECO:0000313|Ensembl:ENSP00000409760}; Flags: Fragment;"]
[55317,"'AP5S1'",212,272,264,249.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0031902///late endosome membrane+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0005829///cytosol+++GO:0005764///lysosome+++GO:0005770///late endosome+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:0015031///protein transport+++GO:0016197///endosomal transport+++GO:0000724///double-strand break repair via homologous recombination","adaptor related protein complex 5 subunit sigma 1","[AP5S1_HUMAN|Reviewed]RecName: Full=AP-5 complex subunit sigma-1; AltName: Full=Adaptor-related protein complex 5 sigma subunit; Short=Sigma5;+++[A2A2L4_HUMAN|Unreviewed]SubName: Full=AP-5 complex subunit sigma-1 {ECO:0000313|Ensembl:ENSP00000405487}; Flags: Fragment;+++[Q5JX74_HUMAN|Unreviewed]SubName: Full=AP-5 complex subunit sigma-1 {ECO:0000313|Ensembl:ENSP00000368892};"]
[5534,"'PPP3R1'",431,328,368,375.666666666667,"04022///cGMP-PKG signaling pathway+++04922///Glucagon signaling pathway+++04020///Calcium signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04921///Oxytocin signaling pathway+++04380///Osteoclast differentiation+++04010///MAPK signaling pathway+++04659///Th17 cell differentiation+++04310///Wnt signaling pathway+++05010///Alzheimer's disease+++04370///VEGF signaling pathway+++05031///Amphetamine addiction+++05152///Tuberculosis+++05166///HTLV-I infection+++04625///C-type lectin receptor signaling pathway+++04724///Glutamatergic synapse+++04218///Cellular senescence+++04720///Long-term potentiation+++04114///Oocyte meiosis+++04658///Th1 and Th2 cell differentiation+++05163///Human cytomegalovirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04924///Renin secretion+++04660///T cell receptor signaling pathway+++05014///Amyotrophic lateral sclerosis (ALS)+++04360///Axon guidance",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0042383///sarcolemma+++GO:0005886///plasma membrane+++GO:0005955///calcineurin complex+++GO:0005654///nucleoplasm","GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0004723///calcium-dependent protein serine/threonine phosphatase activity+++GO:0016018///cyclosporin A binding+++GO:0019902///phosphatase binding+++GO:0005516///calmodulin binding","GO:0006470///protein dephosphorylation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0033173///calcineurin-NFAT signaling cascade","protein phosphatase 3 regulatory subunit B, alpha","[CANB1_HUMAN|Reviewed]RecName: Full=Calcineurin subunit B type 1; AltName: Full=Protein phosphatase 2B regulatory subunit 1; AltName: Full=Protein phosphatase 3 regulatory subunit B alpha isoform 1;+++[D3YTA9_HUMAN|Unreviewed]SubName: Full=Calcineurin subunit B type 1 {ECO:0000313|Ensembl:ENSP00000387216};+++[F6U1T9_HUMAN|Unreviewed]SubName: Full=Calcineurin subunit B type 1 {ECO:0000313|Ensembl:ENSP00000387148};"]
[55349,"'CHDH'",124,103,158,128.333333333333,"00260///Glycine, serine and threonine metabolism+++01100///Metabolic pathways",null,"M00555///Betaine biosynthesis, choline => betaine","R01025///choline:acceptor 1-oxidoreductase   Choline + Acceptor <=> Betaine aldehyde + Reduced acceptor","GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane","GO:0050660///flavin adenine dinucleotide binding+++GO:0016491///oxidoreductase activity+++GO:0008812///choline dehydrogenase activity+++GO:0016614///oxidoreductase activity, acting on CH-OH group of donors+++GO:0005515///protein binding","GO:0042426///choline catabolic process+++GO:0055114///oxidation-reduction process+++GO:0019285///glycine betaine biosynthetic process from choline","choline dehydrogenase","[CHDH_HUMAN|Reviewed]RecName: Full=Choline dehydrogenase, mitochondrial; Short=CDH; Short=CHD; EC=1.1.99.1; Flags: Precursor;+++[A0A024R301_HUMAN|Unreviewed]SubName: Full=Choline dehydrogenase, isoform CRA_a {ECO:0000313|EMBL:EAW65297.1};+++[C9J7D8_HUMAN|Unreviewed]SubName: Full=Choline dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000418273}; Flags: Fragment;+++[C9JYW4_HUMAN|Unreviewed]SubName: Full=Choline dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000419863}; Flags: Fragment;"]
[55425,"'GPALPP1'",216,172,212,200,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0048786///presynaptic active zone+++GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0032991///protein-containing complex+++GO:0070761///pre-snoRNP complex+++GO:0008023///transcription elongation factor complex+++GO:0005726///perichromatin fibrils+++GO:0016363///nuclear matrix","GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0051117///ATPase binding+++GO:0030674///protein binding, bridging","GO:0051259///protein complex oligomerization+++GO:0000492///box C/D snoRNP assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006396///RNA processing","GPALPP motifs containing 1","[GPAM1_HUMAN|Reviewed]RecName: Full=GPALPP motifs-containing protein 1; AltName: Full=Lipopolysaccharide-specific response protein 7;+++[A0A024RDS7_HUMAN|Unreviewed]SubName: Full=KIAA1704, isoform CRA_a {ECO:0000313|EMBL:EAX08723.1};+++[A0A087WW86_HUMAN|Unreviewed]SubName: Full=GPALPP motifs-containing protein 1 {ECO:0000313|Ensembl:ENSP00000480028};+++[A0A0A0MRI1_HUMAN|Unreviewed]SubName: Full=GPALPP motifs-containing protein 1 {ECO:0000313|Ensembl:ENSP00000355211}; SubName: Full=KIAA1704, isoform CRA_c {ECO:0000313|EMBL:EAX08722.1};+++[L8EB00_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA1704 {ECO:0000313|EMBL:CCQ43603.1};"]
[5546,"'PRCC'",1519,1551,1492,1520.66666666667,"05202///Transcriptional misregulation in cancer+++05211///Renal cell carcinoma",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0005515///protein binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007049///cell cycle","proline rich mitotic checkpoint control factor","[PRCC_HUMAN|Reviewed]RecName: Full=Proline-rich protein PRCC; AltName: Full=Papillary renal cell carcinoma translocation-associated gene protein;+++[A0A0S2Z456_HUMAN|Unreviewed]SubName: Full=Papillary renal cell carcinoma isoform 1 {ECO:0000313|EMBL:ALQ33731.1}; Flags: Fragment;+++[A0A0S2Z470_HUMAN|Unreviewed]SubName: Full=Papillary renal cell carcinoma isoform 3 {ECO:0000313|EMBL:ALQ33733.1}; Flags: Fragment;+++[A0A0S2Z483_HUMAN|Unreviewed]SubName: Full=Papillary renal cell carcinoma isoform 2 {ECO:0000313|EMBL:ALQ33732.1};+++[H0Y679_HUMAN|Unreviewed]SubName: Full=Proline-rich protein PRCC {ECO:0000313|Ensembl:ENSP00000403560}; Flags: Fragment;+++[H0YE12_HUMAN|Unreviewed]SubName: Full=Proline-rich protein PRCC {ECO:0000313|Ensembl:ENSP00000434762}; Flags: Fragment;+++[Q96FT4_HUMAN|Unreviewed]SubName: Full=Papillary renal cell carcinoma (Translocation-associated) {ECO:0000313|EMBL:AAH10450.1};"]
[5553,"'PRG2'",1,0,0,0.333333333333333,"05310///Asthma",{"$nulls":3},"GO:0030133///transport vesicle+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome","GO:0008201///heparin binding+++GO:0030246///carbohydrate binding","GO:0002215///defense response to nematode+++GO:0043312///neutrophil degranulation+++GO:0042742///defense response to bacterium+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032753///positive regulation of interleukin-4 production+++GO:0042035///regulation of cytokine biosynthetic process","proteoglycan 2, pro eosinophil major basic protein","[PRG2_HUMAN|Reviewed]RecName: Full=Bone marrow proteoglycan; Short=BMPG; AltName: Full=Proteoglycan 2; Contains: RecName: Full=Eosinophil granule major basic protein; Short=EMBP; Short=MBP; AltName: Full=Pregnancy-associated major basic protein; Flags: Precursor;+++[A8MZH3_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000380973};+++[C9J6H1_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000405882}; Flags: Fragment;+++[E9PJ72_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000435641};+++[E9PKX9_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000435243};+++[E9PLQ9_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000431335};+++[E9PLU9_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000431267};+++[E9PMR5_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000432988};+++[E9PNZ1_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000437063}; Flags: Fragment;+++[E9PQE7_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000436830};+++[E9PSE2_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000434011};+++[F5H7N4_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000442393};+++[F8WEU6_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000346545};+++[H0YEA2_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000435322};+++[H0YF02_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000436951};+++[H7BYR8_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000380967};+++[J3KS94_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000462374}; Flags: Fragment;+++[J3KT01_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000462734}; Flags: Fragment;+++[J3KT34_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000462780}; Flags: Fragment;+++[J3QKL5_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000463137}; Flags: Fragment;+++[J3QKN5_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000463164}; Flags: Fragment;+++[J3QL64_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000463403};+++[J3QQK6_HUMAN|Unreviewed]SubName: Full=Myelin basic protein {ECO:0000313|Ensembl:ENSP00000463780};"]
[55540,"'IL17RB'",12,20,14,15.3333333333333,"04657///IL-17 signaling pathway+++04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region","GO:0004896///cytokine receptor activity+++GO:0030368///interleukin-17 receptor activity","GO:0019221///cytokine-mediated signaling pathway+++GO:2000664///positive regulation of interleukin-5 secretion+++GO:2000667///positive regulation of interleukin-13 secretion+++GO:0097400///interleukin-17-mediated signaling pathway+++GO:0006952///defense response+++GO:0050729///positive regulation of inflammatory response+++GO:0001558///regulation of cell growth","interleukin 17 receptor B","[I17RB_HUMAN|Reviewed]RecName: Full=Interleukin-17 receptor B; Short=IL-17 receptor B; Short=IL-17RB; AltName: Full=Cytokine receptor-like 4; AltName: Full=IL-17 receptor homolog 1; Short=IL-17Rh1; Short=IL17Rh1; AltName: Full=Interleukin-17B receptor; Short=IL-17B receptor; Flags: Precursor;+++[C9IZN0_HUMAN|Unreviewed]SubName: Full=Interleukin-17 receptor B {ECO:0000313|Ensembl:ENSP00000418638}; Flags: Fragment;"]
[55596,"'ZCCHC8'",163,156,148,155.666666666667,{"$nulls":4},"GO:0031499///TRAMP complex+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex","GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome","zinc finger CCHC-type containing 8","[ZCHC8_HUMAN|Reviewed]RecName: Full=Zinc finger CCHC domain-containing protein 8; AltName: Full=TRAMP-like complex RNA-binding factor ZCCHC8;+++[F5GX80_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000441112}; Flags: Fragment;+++[F5GYI9_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000440234}; Flags: Fragment;+++[F5H6J5_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000437578}; Flags: Fragment;"]
[55603,"'TENT5A'",3499,2879,2689,3022.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0003723///RNA binding+++GO:1990817///RNA adenylyltransferase activity+++GO:0005515///protein binding","GO:0009617///response to bacterium","terminal nucleotidyltransferase 5A","[TET5A_HUMAN|Reviewed]RecName: Full=Terminal nucleotidyltransferase 5A {ECO:0000305}; EC=2.7.7.- {ECO:0000305|PubMed:27060136}; AltName: Full=HBV X-transactivated gene 11 protein {ECO:0000303|Ref.2}; AltName: Full=HBV XAg-transactivated protein 11 {ECO:0000303|Ref.2};+++[B6E614_HUMAN|Unreviewed]SubName: Full=HBV XAg-transactivated protein 11 splice variant 1 {ECO:0000313|EMBL:ACI29324.1};+++[H0Y5Y3_HUMAN|Unreviewed]SubName: Full=Terminal nucleotidyltransferase 5A {ECO:0000313|Ensembl:ENSP00000401884}; Flags: Fragment;+++[H0Y6D7_HUMAN|Unreviewed]SubName: Full=Terminal nucleotidyltransferase 5A {ECO:0000313|Ensembl:ENSP00000404872}; Flags: Fragment;+++[L8E8C7_HUMAN|Unreviewed]SubName: Full=Alternative protein FAM46A {ECO:0000313|EMBL:CCQ43560.1};+++[Q5TF85_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 46, member A, isoform CRA_a {ECO:0000313|EMBL:EAW48691.1}; SubName: Full=Terminal nucleotidyltransferase 5A {ECO:0000313|Ensembl:ENSP00000358771};+++[W5ZL11_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 46 member A {ECO:0000313|EMBL:AHI42044.1}; Flags: Fragment;+++[W5ZLG2_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 46 member A {ECO:0000313|EMBL:AHI42043.1}; Flags: Fragment;"]
[55616,"'ASAP3'",1034,905,981,973.333333333333,"04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0001726///ruffle","GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0043547///positive regulation of GTPase activity+++GO:0016477///cell migration+++GO:0051492///regulation of stress fiber assembly","ArfGAP with SH3 domain, ankyrin repeat and PH domain 3","[ASAP3_HUMAN|Reviewed]RecName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3; AltName: Full=Development and differentiation-enhancing factor-like 1; AltName: Full=Protein up-regulated in liver cancer 1;+++[A0A024RAB1_HUMAN|Unreviewed]SubName: Full=Development and differentiation enhancing factor-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW95053.1};+++[A0A087X0Y5_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000483740};+++[B4DRP2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53171, highly similar to Development and differentiation-enhancing factor-like 1 {ECO:0000313|EMBL:BAG61354.1};+++[E9PS98_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000435858};+++[H0YE36_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000434897}; Flags: Fragment;+++[H0YEB0_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000435394}; Flags: Fragment;+++[H0YER8_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000436439}; Flags: Fragment;+++[Q6PJ46_HUMAN|Unreviewed]SubName: Full=ASAP3 protein {ECO:0000313|EMBL:AAH23519.1};+++[V9GY49_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000476400}; Flags: Fragment;"]
[55635,"'DEPDC1'",2,1,4,2.33333333333333,{"$nulls":4},"GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus","GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity","DEP domain containing 1","[DEP1A_HUMAN|Reviewed]RecName: Full=DEP domain-containing protein 1A;+++[E9PL61_HUMAN|Unreviewed]SubName: Full=DEP domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000431477}; Flags: Fragment;+++[H0YES2_HUMAN|Unreviewed]SubName: Full=DEP domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000436464}; Flags: Fragment;"]
[55653,"'BCAS4'",147,160,160,155.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031083///BLOC-1 complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0003785///actin monomer binding+++GO:0048487///beta-tubulin binding+++GO:0003677///DNA binding+++GO:0042277///peptide binding+++GO:0005507///copper ion binding","GO:0050805///negative regulation of synaptic transmission+++GO:0007015///actin filament organization+++GO:0010629///negative regulation of gene expression+++GO:0010035///response to inorganic substance+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0009743///response to carbohydrate+++GO:0045773///positive regulation of axon extension+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0033484///nitric oxide homeostasis+++GO:0019934///cGMP-mediated signaling+++GO:0030334///regulation of cell migration+++GO:0007614///short-term memory+++GO:0006351///transcription, DNA-templated+++GO:0044849///estrous cycle+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0031668///cellular response to extracellular stimulus+++GO:0051965///positive regulation of synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032091///negative regulation of protein binding+++GO:0046907///intracellular transport+++GO:0010835///regulation of protein ADP-ribosylation","breast carcinoma amplified sequence 4","[BCAS4_HUMAN|Reviewed]RecName: Full=Breast carcinoma-amplified sequence 4;+++[A0A0C4DGS6_HUMAN|Unreviewed]SubName: Full=Breast carcinoma-amplified sequence 4 {ECO:0000313|Ensembl:ENSP00000477167};+++[A0A0C4DH49_HUMAN|Unreviewed]SubName: Full=Breast carcinoma-amplified sequence 4 {ECO:0000313|Ensembl:ENSP00000392594}; Flags: Fragment;+++[H7C4Y8_HUMAN|Unreviewed]SubName: Full=Breast carcinoma-amplified sequence 4 {ECO:0000313|Ensembl:ENSP00000418559};"]
[55670,"'PEX26'",798.02,644,736.99,726.336666666667,"04146///Peroxisome","H01342///Zellweger syndrome (ZS)+++H00177///Adrenoleukodystrophy, neonatal (NALD)+++H00205///Peroxisome biogenesis disorder+++H00204///Infantile Refsum disease (IRD)",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0051117///ATPase binding+++GO:0044877///protein-containing complex binding","GO:0045046///protein import into peroxisome membrane+++GO:0016558///protein import into peroxisome matrix+++GO:0015031///protein transport+++GO:0006625///protein targeting to peroxisome","peroxisomal biogenesis factor 26","[PEX26_HUMAN|Reviewed]RecName: Full=Peroxisome assembly protein 26; AltName: Full=Peroxin-26;+++[A0A024R100_HUMAN|Unreviewed]SubName: Full=Peroxisomal biogenesis factor 26 isoform 1 {ECO:0000313|EMBL:ALQ34167.1}; SubName: Full=Peroxisome biogenesis factor 26, isoform CRA_a {ECO:0000313|EMBL:EAW57783.1};+++[A0A0S2Z5M7_HUMAN|Unreviewed]SubName: Full=Peroxisomal biogenesis factor 26 isoform 2 {ECO:0000313|EMBL:ALQ34168.1}; Flags: Fragment;+++[E9PRC5_HUMAN|Unreviewed]SubName: Full=Peroxisome assembly protein 26 {ECO:0000313|Ensembl:ENSP00000434235};+++[Q7Z2D7_HUMAN|Unreviewed]SubName: Full=Pex26pT35insC/del223-271 {ECO:0000313|EMBL:BAC78803.1};"]
[55691,"'FRMD4A'",1112,894,1114,1040,"04140///Autophagy - animal+++03040///Spliceosome+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005923///bicellular tight junction+++GO:0005912///adherens junction+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030054///cell junction","GO:0030674///protein binding, bridging","GO:0090162///establishment of epithelial cell polarity","FERM domain containing 4A","[FRM4A_HUMAN|Reviewed]RecName: Full=FERM domain-containing protein 4A;+++[A0A0J9YWI3_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000487974}; Flags: Fragment;+++[A0A0J9YXB2_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000488325}; Flags: Fragment;+++[A0A0J9YYA7_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000488764}; Flags: Fragment;+++[A0A1W2PQE7_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000492091}; Flags: Fragment;+++[Q5T376_HUMAN|Unreviewed]SubName: Full=FERM domain containing 4A, isoform CRA_c {ECO:0000313|EMBL:EAW86277.1}; SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000264546}; Flags: Fragment;+++[Q9NW91_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10210 fis, clone HEMBA1006344, weakly similar to RADIXIN {ECO:0000313|EMBL:BAA91492.1};+++[S4R324_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000473870};+++[S4R3Y6_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000474863};"]
[55706,"'NDC1'",241,189,205,211.666666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0031965///nuclear membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016021///integral component of membrane+++GO:0015629///actin cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0070762///nuclear pore transmembrane ring+++GO:0005643///nuclear pore","GO:0017056///structural constituent of nuclear pore","GO:0006406///mRNA export from nucleus+++GO:0051028///mRNA transport+++GO:0007283///spermatogenesis+++GO:0016032///viral process+++GO:0007129///synapsis+++GO:0031081///nuclear pore distribution+++GO:0051292///nuclear pore complex assembly+++GO:0015031///protein transport+++GO:0006999///nuclear pore organization","NDC1 transmembrane nucleoporin","[NDC1_HUMAN|Reviewed]RecName: Full=Nucleoporin NDC1; Short=hNDC1; AltName: Full=Transmembrane protein 48;"]
[55727,"'BTBD7'",678,448,526,550.666666666667,{"$nulls":4},"GO:0005634///nucleus",null,"GO:0060693///regulation of branching involved in salivary gland morphogenesis+++GO:0007275///multicellular organism development","BTB domain containing 7","[BTBD7_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein 7;+++[A5D8X4_HUMAN|Unreviewed]SubName: Full=BTB (POZ) domain containing 7 {ECO:0000313|EMBL:AAI41851.1};+++[G3V2J4_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000450704}; Flags: Fragment;+++[G3V3T2_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000451408};+++[H0YJ41_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000450778}; Flags: Fragment;+++[H3BLV3_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000347246}; Flags: Fragment;"]
[55744,"'COA1'",383,375.93,383.64,380.856666666667,"04714///Thermogenesis",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0003735///structural constituent of ribosome+++GO:0005524///ATP binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0033617///mitochondrial respiratory chain complex IV assembly","cytochrome c oxidase assembly factor 1 homolog","[COA1_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase assembly factor 1 homolog; AltName: Full=Mitochondrial translation regulation assembly intermediate of cytochrome c oxidase protein of 15 kDa;+++[A0A024RA60_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW94167.1};+++[C9J6J1_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase assembly factor 1 homolog {ECO:0000313|Ensembl:ENSP00000417046}; Flags: Fragment;+++[C9JA07_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase assembly factor 1 homolog {ECO:0000313|Ensembl:ENSP00000405582}; Flags: Fragment;+++[F2Z2D1_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase assembly factor 1 homolog {ECO:0000313|Ensembl:ENSP00000400271};+++[F2Z2J3_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase assembly factor 1 homolog {ECO:0000313|Ensembl:ENSP00000410365};+++[F8WBS2_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase assembly factor 1 homolog {ECO:0000313|Ensembl:ENSP00000411540};"]
[5576,"'PRKAR2A'",1120.6,911.01,1018.99,1016.86666666667,"04910///Insulin signaling pathway","H01431///Cushing's syndrome+++H01820///Carney complex+++H01102///Pituitary adenomas+++H00260///Pigmented micronodular adrenocortical disease (PPNAD)",null,null,"GO:0044853///plasma membrane raft+++GO:0005952///cAMP-dependent protein kinase complex+++GO:0097546///ciliary base+++GO:0005829///cytosol+++GO:0005930///axoneme+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome","GO:0000166///nucleotide binding+++GO:0008603///cAMP-dependent protein kinase regulator activity+++GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0016301///kinase activity+++GO:0030552///cAMP binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity","GO:0019934///cGMP-mediated signaling+++GO:0016310///phosphorylation+++GO:2000480///negative regulation of cAMP-dependent protein kinase activity+++GO:0001932///regulation of protein phosphorylation+++GO:0007596///blood coagulation+++GO:0071377///cellular response to glucagon stimulus+++GO:0034199///activation of protein kinase A activity+++GO:0007339///binding of sperm to zona pellucida+++GO:0045859///regulation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0003091///renal water homeostasis","protein kinase cAMP-dependent type II regulatory subunit alpha","[KAP2_HUMAN|Reviewed]RecName: Full=cAMP-dependent protein kinase type II-alpha regulatory subunit;+++[A0A024R2W3_HUMAN|Unreviewed]SubName: Full=Protein kinase cAMP-dependent regulatory type II alpha isoform 2 {ECO:0000313|EMBL:ALQ33735.1}; SubName: Full=Protein kinase, cAMP-dependent, regulatory, type II, alpha, isoform CRA_a {ECO:0000313|EMBL:EAW64928.1};+++[A0A0S2Z472_HUMAN|Unreviewed]SubName: Full=Protein kinase cAMP-dependent regulatory type II alpha isoform 1 {ECO:0000313|EMBL:ALQ33734.1}; Flags: Fragment;+++[A8KAH7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75444, highly similar to Homo sapiens protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A), mRNA {ECO:0000313|EMBL:BAF85731.1};+++[C9J830_HUMAN|Unreviewed]SubName: Full=cAMP-dependent protein kinase type II-alpha regulatory subunit {ECO:0000313|Ensembl:ENSP00000411432}; Flags: Fragment;+++[H7C1L0_HUMAN|Unreviewed]SubName: Full=cAMP-dependent protein kinase type II-alpha regulatory subunit {ECO:0000313|Ensembl:ENSP00000400840}; Flags: Fragment;+++[H7C330_HUMAN|Unreviewed]SubName: Full=cAMP-dependent protein kinase type II-alpha regulatory subunit {ECO:0000313|Ensembl:ENSP00000409239}; Flags: Fragment;+++[H7C4A9_HUMAN|Unreviewed]SubName: Full=cAMP-dependent protein kinase type II-alpha regulatory subunit {ECO:0000313|Ensembl:ENSP00000416438}; Flags: Fragment;"]
[55778,"'ZNF839'",92,75,102,89.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding",null,"zinc finger protein 839","[ZN839_HUMAN|Reviewed]RecName: Full=Zinc finger protein 839; AltName: Full=Renal carcinoma antigen NY-REN-50;+++[H0YKI3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 839 {ECO:0000313|Ensembl:ENSP00000452819}; Flags: Fragment;+++[H0YKY1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 839 {ECO:0000313|Ensembl:ENSP00000452983}; Flags: Fragment;+++[H0YLB6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 839 {ECO:0000313|Ensembl:ENSP00000453137}; Flags: Fragment;+++[H0YM06_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 839 {ECO:0000313|Ensembl:ENSP00000453415}; Flags: Fragment;+++[H0YM94_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 839 {ECO:0000313|Ensembl:ENSP00000453515}; Flags: Fragment;+++[H0YMU1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 839 {ECO:0000313|Ensembl:ENSP00000453744}; Flags: Fragment;+++[H0YNU6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 839 {ECO:0000313|Ensembl:ENSP00000454159}; Flags: Fragment;"]
[55791,"'LRIF1'",195,162,133,163.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005815///microtubule organizing center+++GO:0031965///nuclear membrane+++GO:0001740///Barr body+++GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0016604///nuclear body+++GO:0005886///plasma membrane+++GO:0001939///female pronucleus+++GO:0000793///condensed chromosome+++GO:0000790///nuclear chromatin+++GO:0005694///chromosome+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0001940///male pronucleus+++GO:0016363///nuclear matrix+++GO:0051233///spindle midzone+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0042974///retinoic acid receptor binding","GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0045830///positive regulation of isotype switching+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining+++GO:0000723///telomere maintenance+++GO:0051574///positive regulation of histone H3-K9 methylation+++GO:0006281///DNA repair+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043247///telomere maintenance in response to DNA damage+++GO:0019827///stem cell population maintenance+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006348///chromatin silencing at telomere+++GO:0006303///double-strand break repair via nonhomologous end joining","ligand dependent nuclear receptor interacting factor 1","[LRIF1_HUMAN|Reviewed]RecName: Full=Ligand-dependent nuclear receptor-interacting factor 1 {ECO:0000305}; AltName: Full=HP1-binding protein enriched in inactive X chromosome protein 1 {ECO:0000303|PubMed:23542155}; Short=HBiX1 {ECO:0000303|PubMed:23542155}; AltName: Full=Receptor-interacting factor 1 {ECO:0000303|PubMed:17455211};+++[H7BZN3_HUMAN|Unreviewed]SubName: Full=Telomere-associated protein RIF1 {ECO:0000313|Ensembl:ENSP00000390486}; Flags: Fragment;+++[H7C2B5_HUMAN|Unreviewed]SubName: Full=Telomere-associated protein RIF1 {ECO:0000313|Ensembl:ENSP00000404882}; Flags: Fragment;"]
[55812,"'SPATA7'",118,121,110,116.333333333333,null,"H00837///Leber congenital amaurosis (LCR)+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0036064///ciliary basal body+++GO:0032391///photoreceptor connecting cilium+++GO:0005654///nucleoplasm+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005739///mitochondrion+++GO:0005930///axoneme","GO:0005515///protein binding","GO:0050896///response to stimulus+++GO:0045494///photoreceptor cell maintenance+++GO:1903546///protein localization to photoreceptor outer segment+++GO:0007601///visual perception+++GO:1903621///protein localization to photoreceptor connecting cilium","spermatogenesis associated 7","[SPAT7_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 7; AltName: Full=HSD-3.1; AltName: Full=Spermatogenesis-associated protein HSD3;+++[G3V287_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450515};+++[G3V2E1_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450606}; Flags: Fragment;+++[G3V2V4_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450882};+++[G3V3D2_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451181};+++[G3V491_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451663};+++[G3V4A9_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451690};+++[G3V5H6_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000452359};+++[G3V5N2_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000452435}; Flags: Fragment;+++[G3V5V8_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000452546};+++[H0YJ48_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450809}; Flags: Fragment;+++[H0YJ93_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451019}; Flags: Fragment;+++[Q6FI63_HUMAN|Unreviewed]SubName: Full=SPATA7 protein {ECO:0000313|EMBL:CAG38594.1};+++[V9HVY9_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 296 {ECO:0000313|EMBL:ACF94506.1}; SubName: Full=Spermatogenesis associated 7, isoform CRA_f {ECO:0000313|EMBL:EAW81381.1};"]
[55829,"'SELENOS'",363,397,367,375.666666666667,"04141///Protein processing in endoplasmic reticulum",null,"M00403///HRD1/SEL1 ERAD complex",null,"GO:0005886///plasma membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0034361///very-low-density lipoprotein particle+++GO:0005737///cytoplasm+++GO:0036502///Derlin-1-VIMP complex+++GO:0036513///Derlin-1 retrotranslocation complex+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0034362///low-density lipoprotein particle+++GO:0016020///membrane+++GO:0005881///cytoplasmic microtubule","GO:0038023///signaling receptor activity+++GO:0005515///protein binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0019899///enzyme binding+++GO:0016209///antioxidant activity+++GO:0051117///ATPase binding","GO:0016567///protein ubiquitination+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0032869///cellular response to insulin stimulus+++GO:0006886///intracellular protein transport+++GO:0046325///negative regulation of glucose import+++GO:0080164///regulation of nitric oxide metabolic process+++GO:0006111///regulation of gluconeogenesis+++GO:0050728///negative regulation of inflammatory response+++GO:0098869///cellular oxidant detoxification+++GO:0032715///negative regulation of interleukin-6 production+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0002865///negative regulation of acute inflammatory response to antigenic stimulus+++GO:0006983///ER overload response+++GO:2000110///negative regulation of macrophage apoptotic process+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0051775///response to redox state+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0034599///cellular response to oxidative stress+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045454///cell redox homeostasis+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0045184///establishment of protein localization+++GO:0051771///negative regulation of nitric-oxide synthase biosynthetic process+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0009749///response to glucose","selenoprotein S","[SELS_HUMAN|Reviewed]RecName: Full=Selenoprotein S {ECO:0000303|PubMed:27645994}; Short=SelS {ECO:0000303|PubMed:12775843}; AltName: Full=VCP-interacting membrane protein {ECO:0000303|PubMed:15215856};+++[A0A182DWI4_HUMAN|Unreviewed]SubName: Full=Selenoprotein S {ECO:0000313|Ensembl:ENSP00000433803};+++[E9PN30_HUMAN|Unreviewed]SubName: Full=Selenoprotein S {ECO:0000313|Ensembl:ENSP00000434842}; Flags: Fragment;+++[Q6GYA4_HUMAN|Unreviewed]SubName: Full=Selenoprotein S {ECO:0000313|EMBL:EAX02295.1}; SubName: Full=VIMP {ECO:0000313|EMBL:AAT46592.1};"]
[55852,"'TEX2'",6632.93,5135.29,6798,6188.74,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008289///lipid binding+++GO:0003674///molecular_function","GO:0007165///signal transduction+++GO:0006869///lipid transport+++GO:0006665///sphingolipid metabolic process","testis expressed 2","[TEX2_HUMAN|Reviewed]RecName: Full=Testis-expressed protein 2; AltName: Full=Transmembrane protein 96;+++[A0A087WVA8_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000479308};+++[J3KRY2_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000462210}; Flags: Fragment;+++[J3KRZ8_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000462230}; Flags: Fragment;+++[J3QKY0_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 2 {ECO:0000313|Ensembl:ENSP00000463286}; Flags: Fragment;+++[Q2YDX6_HUMAN|Unreviewed]SubName: Full=TEX2 protein {ECO:0000313|EMBL:AAI08280.1}; Flags: Fragment;+++[Q7L166_HUMAN|Unreviewed]SubName: Full=TEX2 protein {ECO:0000313|EMBL:AAH33661.2}; Flags: Fragment;"]
[5587,"'PRKD1'",135,118,97,116.666666666667,"04015///Rap1 signaling pathway+++04925///Aldosterone synthesis and secretion",{"$nulls":3},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005802///trans-Golgi network+++GO:0005938///cell cortex+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0000421///autophagosome membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004697///protein kinase C activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:0031647///regulation of protein stability+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0006915///apoptotic process+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0007030///Golgi organization+++GO:0008283///cell proliferation+++GO:0030148///sphingolipid biosynthetic process+++GO:0045806///negative regulation of endocytosis+++GO:0038033///positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway+++GO:0048193///Golgi vesicle transport+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0045087///innate immune response+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0060548///negative regulation of cell death+++GO:0030154///cell differentiation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0035556///intracellular signal transduction+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0007399///nervous system development+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0089700///protein kinase D signaling+++GO:0007229///integrin-mediated signaling pathway+++GO:1901727///positive regulation of histone deacetylase activity+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0002376///immune system process+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0007165///signal transduction+++GO:0001525///angiogenesis+++GO:0016310///phosphorylation+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:2001028///positive regulation of endothelial cell chemotaxis+++GO:0050829///defense response to Gram-negative bacterium+++GO:0010508///positive regulation of autophagy+++GO:0071447///cellular response to hydroperoxide+++GO:0034198///cellular response to amino acid starvation+++GO:2001044///regulation of integrin-mediated signaling pathway+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0010837///regulation of keratinocyte proliferation+++GO:0010976///positive regulation of neuron projection development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0042307///positive regulation of protein import into nucleus+++GO:0010595///positive regulation of endothelial cell migration+++GO:0006954///inflammatory response+++GO:0034599///cellular response to oxidative stress","protein kinase D1","[KPCD1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase D1; EC=2.7.11.13; AltName: Full=Protein kinase C mu type; AltName: Full=Protein kinase D; AltName: Full=nPKC-D1; AltName: Full=nPKC-mu;+++[F8VZ98_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase D1 {ECO:0000313|Ensembl:ENSP00000446866}; Flags: Fragment;+++[F8WBA3_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein kinase {ECO:0000256|PIRNR:PIRNR000552}; EC=2.7.11.13 {ECO:0000256|PIRNR:PIRNR000552};+++[H0YHL5_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase D1 {ECO:0000313|Ensembl:ENSP00000447333}; Flags: Fragment;+++[H0YHS9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase D1 {ECO:0000313|Ensembl:ENSP00000447723}; Flags: Fragment;+++[Q1KKQ2_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein kinase {ECO:0000256|PIRNR:PIRNR000552}; EC=2.7.11.13 {ECO:0000256|PIRNR:PIRNR000552};"]
[55879,"'GABRQ'",2,1,4,2.33333333333333,"04080///Neuroactive ligand-receptor interaction+++04727///GABAergic synapse+++05033///Nicotine addiction+++04723///Retrograde endocannabinoid signaling+++05032///Morphine addiction",{"$nulls":3},"GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0045211///postsynaptic membrane+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0045202///synapse+++GO:1902711///GABA-A receptor complex+++GO:0043235///receptor complex+++GO:0034707///chloride channel complex","GO:0005326///neurotransmitter transporter activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005216///ion channel activity+++GO:0004890///GABA-A receptor activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005254///chloride channel activity","GO:0006836///neurotransmitter transport+++GO:0034220///ion transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:0006821///chloride transport+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007165///signal transduction+++GO:0042391///regulation of membrane potential+++GO:0050877///nervous system process","gamma-aminobutyric acid type A receptor theta subunit","[GBRT_HUMAN|Reviewed]RecName: Full=Gamma-aminobutyric acid receptor subunit theta; AltName: Full=GABA(A) receptor subunit theta; Flags: Precursor;"]
[55917,"'CTTNBP2NL'",937,641,729,769,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton","GO:0051721///protein phosphatase 2A binding+++GO:0005515///protein binding","GO:0032410///negative regulation of transporter activity+++GO:0006470///protein dephosphorylation+++GO:0034763///negative regulation of transmembrane transport","CTTNBP2 N-terminal like","[CT2NL_HUMAN|Reviewed]RecName: Full=CTTNBP2 N-terminal-like protein;+++[A0A024R0C7_HUMAN|Unreviewed]SubName: Full=CTTNBP2 N-terminal like, isoform CRA_b {ECO:0000313|EMBL:EAW56517.1};+++[B1AMN7_HUMAN|Unreviewed]SubName: Full=CTTNBP2 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000390976}; Flags: Fragment;"]
[5593,"'PRKG2'",40.05,40,19,33.0166666666667,"04540///Gap junction+++04923///Regulation of lipolysis in adipocytes+++04970///Salivary secretion+++04740///Olfactory transduction+++04730///Long-term depression+++04714///Thermogenesis+++04611///Platelet activation+++04924///Renin secretion+++04713///Circadian entrainment+++04022///cGMP-PKG signaling pathway",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin+++R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate","GO:0031965///nuclear membrane+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0030553///cGMP binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004692///cGMP-dependent protein kinase activity","GO:0072659///protein localization to plasma membrane+++GO:2001226///negative regulation of chloride transport+++GO:0051186///cofactor metabolic process+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","protein kinase cGMP-dependent 2","[KGP2_HUMAN|Reviewed]RecName: Full=cGMP-dependent protein kinase 2; Short=cGK 2; Short=cGK2; EC=2.7.11.12; AltName: Full=cGMP-dependent protein kinase II; Short=cGKII;+++[A0A140VJM3_HUMAN|Unreviewed]RecName: Full=cGMP-dependent protein kinase {ECO:0000256|PIRNR:PIRNR000559}; EC=2.7.11.12 {ECO:0000256|PIRNR:PIRNR000559};+++[B4DLF9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56988, highly similar to cGMP-dependent protein kinase 2 {ECO:0000313|EMBL:BAG59521.1};+++[B7ZA25_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79039, highly similar to cGMP-dependent protein kinase 2 {ECO:0000313|EMBL:BAH14511.1}; SubName: Full=cGMP-dependent protein kinase 2 {ECO:0000313|Ensembl:ENSP00000439967};"]
[56006,"'SMG9'",806,893,902,867,{"$nulls":4},"GO:0005622///intracellular+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0007420///brain development+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0001654///eye development+++GO:0007507///heart development","SMG9, nonsense mediated mRNA decay factor","[SMG9_HUMAN|Reviewed]RecName: Full=Protein SMG9 {ECO:0000305}; AltName: Full=Protein SMG-9 {ECO:0000303|PubMed:19417104};+++[A0A024R0Q0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW57226.1};+++[M0QX70_HUMAN|Unreviewed]SubName: Full=Protein SMG9 {ECO:0000313|Ensembl:ENSP00000468941}; Flags: Fragment;+++[M0QYR7_HUMAN|Unreviewed]SubName: Full=Protein SMG9 {ECO:0000313|Ensembl:ENSP00000470031}; Flags: Fragment;+++[M0QZC7_HUMAN|Unreviewed]SubName: Full=Protein SMG9 {ECO:0000313|Ensembl:ENSP00000470451}; Flags: Fragment;+++[M0QZH1_HUMAN|Unreviewed]SubName: Full=Protein SMG9 {ECO:0000313|Ensembl:ENSP00000470541}; Flags: Fragment;+++[M0R0U0_HUMAN|Unreviewed]SubName: Full=Protein SMG9 {ECO:0000313|Ensembl:ENSP00000471442}; Flags: Fragment;+++[M0R2N0_HUMAN|Unreviewed]SubName: Full=Protein SMG9 {ECO:0000313|Ensembl:ENSP00000472684}; Flags: Fragment;"]
[5605,"'MAP2K2'",3900,4648,3999,4182.33333333333,"01522///Endocrine resistance+++04620///Toll-like receptor signaling pathway+++04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway+++04916///Melanogenesis+++04730///Long-term depression+++04370///VEGF signaling pathway+++04068///FoxO signaling pathway+++05220///Chronic myeloid leukemia+++05223///Non-small cell lung cancer+++05020///Prion diseases+++05213///Endometrial cancer+++05200///Pathways in cancer+++05161///Hepatitis B+++04140///Autophagy - animal+++04910///Insulin signaling pathway+++04012///ErbB signaling pathway+++04150///mTOR signaling pathway+++04540///Gap junction+++05206///MicroRNAs in cancer+++05231///Choline metabolism in cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05221///Acute myeloid leukemia+++05225///Hepatocellular carcinoma+++04015///Rap1 signaling pathway+++05210///Colorectal cancer+++04010///MAPK signaling pathway+++04919///Thyroid hormone signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++04921///Oxytocin signaling pathway+++04810///Regulation of actin cytoskeleton+++05211///Renal cell carcinoma+++04917///Prolactin signaling pathway+++04071///Sphingolipid signaling pathway+++04934///Cushing's syndrome+++04151///PI3K-Akt signaling pathway+++04722///Neurotrophin signaling pathway+++05165///Human papillomavirus infection+++04014///Ras signaling pathway+++04660///T cell receptor signaling pathway+++04662///B cell receptor signaling pathway+++05205///Proteoglycans in cancer+++05215///Prostate cancer+++05163///Human cytomegalovirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05214///Glioma+++05224///Breast cancer+++05164///Influenza A+++04210///Apoptosis+++04664///Fc epsilon RI signaling pathway+++04024///cAMP signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04072///Phospholipase D signaling pathway+++04066///HIF-1 signaling pathway+++04218///Cellular senescence+++05230///Central carbon metabolism in cancer+++05216///Thyroid cancer+++04720///Long-term potentiation+++04926///Relaxin signaling pathway+++05219///Bladder cancer+++04915///Estrogen signaling pathway+++04270///Vascular smooth muscle contraction+++05218///Melanoma+++04912///GnRH signaling pathway+++05226///Gastric cancer","H00523///Noonan syndrome and related disorders","M00687///MAPK (ERK1/2) signaling",null,"GO:0005769///early endosome+++GO:0005874///microtubule+++GO:0005576///extracellular region+++GO:0005770///late endosome+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005778///peroxisomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005911///cell-cell junction+++GO:0005739///mitochondrion","GO:0030165///PDZ domain binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0046872///metal ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0097110///scaffold protein binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0004708///MAP kinase kinase activity+++GO:0016740///transferase activity","GO:0031098///stress-activated protein kinase signaling cascade+++GO:0036289///peptidyl-serine autophosphorylation+++GO:0000187///activation of MAPK activity+++GO:0023014///signal transduction by protein phosphorylation+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0032147///activation of protein kinase activity+++GO:0006468///protein phosphorylation+++GO:0032872///regulation of stress-activated MAPK cascade+++GO:1903800///positive regulation of production of miRNAs involved in gene silencing by miRNA+++GO:0070371///ERK1 and ERK2 cascade+++GO:2000641///regulation of early endosome to late endosome transport+++GO:0000165///MAPK cascade+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0016310///phosphorylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090170///regulation of Golgi inheritance+++GO:0010629///negative regulation of gene expression","mitogen-activated protein kinase kinase 2","[MP2K2_HUMAN|Reviewed]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 2; Short=MAP kinase kinase 2; Short=MAPKK 2; EC=2.7.12.2 {ECO:0000269|PubMed:10409742}; AltName: Full=ERK activator kinase 2; AltName: Full=MAPK/ERK kinase 2; Short=MEK 2;+++[B3KS97_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase 2, isoform CRA_d {ECO:0000313|EMBL:EAW69265.1}; SubName: Full=cDNA FLJ35806 fis, clone TESTI2005987, highly similar to Dual specificity mitogen-activated protein kinase kinase 2 {ECO:0000313|EMBL:BAG52659.1};+++[G5E9C7_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000378336}; SubName: Full=Mitogen-activated protein kinase kinase 2, isoform CRA_b {ECO:0000313|EMBL:EAW69263.1};+++[M0R1B6_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000471763}; Flags: Fragment;"]
[56110,"'PCDHGA5'",89.82,81.61,144.72,105.383333333333,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005759///mitochondrial matrix","GO:0016491///oxidoreductase activity+++GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0048037///cofactor binding+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0051287///NAD binding+++GO:0004470///malic enzyme activity+++GO:0005509///calcium ion binding+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0046872///metal ion binding","GO:0072592///oxygen metabolic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0006090///pyruvate metabolic process+++GO:0009060///aerobic respiration+++GO:0006099///tricarboxylic acid cycle+++GO:0006108///malate metabolic process+++GO:0055114///oxidation-reduction process","protocadherin gamma subfamily A, 5","[PCDG5_HUMAN|Reviewed]RecName: Full=Protocadherin gamma-A5; Short=PCDH-gamma-A5; Flags: Precursor;+++[E9PKA0_HUMAN|Unreviewed]SubName: Full=NADP-dependent malic enzyme, mitochondrial {ECO:0000313|Ensembl:ENSP00000435427}; Flags: Fragment;+++[E9PMB9_HUMAN|Unreviewed]RecName: Full=Malic enzyme {ECO:0000256|RuleBase:RU003426}; Flags: Fragment;+++[E9PND9_HUMAN|Unreviewed]SubName: Full=NADP-dependent malic enzyme, mitochondrial {ECO:0000313|Ensembl:ENSP00000437204}; Flags: Fragment;+++[E9PNN2_HUMAN|Unreviewed]SubName: Full=NADP-dependent malic enzyme, mitochondrial {ECO:0000313|Ensembl:ENSP00000434690}; Flags: Fragment;+++[L8ECD3_HUMAN|Unreviewed]SubName: Full=Alternative protein ME3 {ECO:0000313|EMBL:CCQ43367.1};+++[O15201_HUMAN|Unreviewed]SubName: Full=Cadherin {ECO:0000313|EMBL:BAA21566.1}; Flags: Fragment;"]
[56124,"'PCDHB12'",46.8,53.52,37.87,46.0633333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0007399///nervous system development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","protocadherin beta 12","[PCDBC_HUMAN|Reviewed]RecName: Full=Protocadherin beta-12; Short=PCDH-beta-12; Flags: Precursor;+++[A0A096LP27_HUMAN|Unreviewed]SubName: Full=Protocadherin beta-12 {ECO:0000313|Ensembl:ENSP00000485352};"]
[56147,"'PCDHA1'",0,4.28,2.96,2.41333333333333,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum","GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0007399///nervous system development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","protocadherin alpha 1","[PCDA1_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-1; Short=PCDH-alpha-1; Flags: Precursor;"]
[56181,"'MTFR1L'",798,744,732,758,{"$nulls":4},"GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0009060///aerobic respiration+++GO:0000266///mitochondrial fission","mitochondrial fission regulator 1 like","[MFR1L_HUMAN|Reviewed]RecName: Full=Mitochondrial fission regulator 1-like;+++[A0A0S2Z5H4_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 54 member B isoform 2 {ECO:0000313|EMBL:ALQ34182.1};+++[A0A0S2Z5H6_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 54 member B isoform 1 {ECO:0000313|EMBL:ALQ34181.1}; Flags: Fragment;+++[C9JF50_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000390841}; Flags: Fragment;+++[E9PIF9_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000432014};+++[E9PJP7_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000435553};+++[E9PLD2_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000435193};+++[E9PLU1_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000431278}; Flags: Fragment;+++[E9PNJ0_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000434773}; Flags: Fragment;+++[E9PPF9_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000432719}; Flags: Fragment;+++[E9PPQ0_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000436954}; Flags: Fragment;+++[E9PRK5_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000432227};+++[E9PRW1_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000434120}; Flags: Fragment;+++[E9PSD6_HUMAN|Unreviewed]SubName: Full=Mitochondrial fission regulator 1-like {ECO:0000313|Ensembl:ENSP00000434038}; Flags: Fragment;"]
[56267,"'KYAT3'",121.59,109.21,107.51,112.77,"00450///Selenocompound metabolism+++05204///Chemical carcinogenesis+++00380///Tryptophan metabolism+++01100///Metabolic pathways",null,null,"R09366///Se-methyl-L-selenocysteine methaneselenol-lyase (deaminating; pyruvate-forming)   Se-Methyl-L-selenocysteine + H2O <=> Pyruvate + Ammonia + Methaneselenol+++R04171///3-Hydroxy-L-kynurenine:2-oxoglutarate aminotransferase   3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate+++R09373///L-methionine:methylselenopyruvate aminotransferase   Se-Methyl-L-selenocysteine + 4-Methylthio-2-oxobutanoic acid <=> Methylselenopyruvate + L-Methionine+++R01956///L-Kynurenine:2-oxoglutarate aminotransferase   L-Kynurenine + 2-Oxoglutarate <=> 4-(2-Aminophenyl)-2,4-dioxobutanoate + L-Glutamate","GO:0000139///Golgi membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0036137///kynurenine aminotransferase activity+++GO:0047804///cysteine-S-conjugate beta-lyase activity+++GO:0016829///lyase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0016212///kynurenine-oxoglutarate transaminase activity+++GO:0042803///protein homodimerization activity+++GO:0016740///transferase activity+++GO:0047315///kynurenine-glyoxylate transaminase activity+++GO:0008483///transaminase activity","GO:0009058///biosynthetic process+++GO:0070189///kynurenine metabolic process+++GO:0097052///L-kynurenine metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006520///cellular amino acid metabolic process","kynurenine aminotransferase 3","[KAT3_HUMAN|Reviewed]RecName: Full=Kynurenine--oxoglutarate transaminase 3; EC=2.6.1.7; AltName: Full=Cysteine-S-conjugate beta-lyase 2; EC=4.4.1.13; AltName: Full=Kynurenine aminotransferase 3 {ECO:0000312|HGNC:HGNC:33238}; AltName: Full=Kynurenine aminotransferase III; Short=KATIII; AltName: Full=Kynurenine--glyoxylate transaminase; EC=2.6.1.63; AltName: Full=Kynurenine--oxoglutarate transaminase III;+++[A0A0A0MRN7_HUMAN|Unreviewed]SubName: Full=Kynurenine--oxoglutarate transaminase 3 {ECO:0000313|Ensembl:ENSP00000359517}; Flags: Fragment;+++[B4DW13_HUMAN|Unreviewed]SubName: Full=HCG23341, isoform CRA_d {ECO:0000313|EMBL:EAW73158.1}; SubName: Full=cDNA FLJ56161, highly similar to Homo sapiens kynurenine aminotransferase III (KAT3), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62875.1}; SubName: Full=cDNA, FLJ78816, highly similar to Homo sapiens kynurenine aminotransferase III (KAT3), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH14288.1};+++[L0R594_HUMAN|Unreviewed]SubName: Full=Alternative protein CCBL2 {ECO:0000313|EMBL:CCO13699.1};"]
[5635,"'PRPSAP1'",285,259,234,259.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0002189///ribose phosphate diphosphokinase complex","GO:0000287///magnesium ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0004749///ribose phosphate diphosphokinase activity+++GO:0004857///enzyme inhibitor activity","GO:0006164///purine nucleotide biosynthetic process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0009165///nucleotide biosynthetic process+++GO:0009116///nucleoside metabolic process+++GO:0043086///negative regulation of catalytic activity+++GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process","phosphoribosyl pyrophosphate synthetase associated protein 1","[KPRA_HUMAN|Reviewed]RecName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 1; Short=PRPP synthase-associated protein 1; AltName: Full=39 kDa phosphoribosypyrophosphate synthase-associated protein; Short=PAP39;+++[A0A024R8M4_HUMAN|Unreviewed]SubName: Full=Phosphoribosyl pyrophosphate synthetase-associated protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW89387.1};+++[B4DP31_HUMAN|Unreviewed]SubName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000314973}; SubName: Full=cDNA FLJ57408, highly similar to Phosphoribosyl pyrophosphatesynthetase-associated protein 1 {ECO:0000313|EMBL:BAG60443.1};+++[C9J168_HUMAN|Unreviewed]SubName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000392838}; Flags: Fragment;+++[C9JKT9_HUMAN|Unreviewed]SubName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000409190}; Flags: Fragment;+++[C9JNQ3_HUMAN|Unreviewed]SubName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000402126}; Flags: Fragment;+++[C9JUN4_HUMAN|Unreviewed]SubName: Full=Phosphoribosyl pyrophosphate synthase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000387494}; Flags: Fragment;"]
[5648,"'MASP1'",13,14,22,16.3333333333333,"04610///Complement and coagulation cascades+++05150///Staphylococcus aureus infection","H01887///3MC syndrome",null,null,"GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm","GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0048306///calcium-dependent protein binding","GO:0045916///negative regulation of complement activation+++GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis+++GO:0002376///immune system process+++GO:0006956///complement activation+++GO:0001867///complement activation, lectin pathway+++GO:0045087///innate immune response","mannan binding lectin serine peptidase 1","[MASP1_HUMAN|Reviewed]RecName: Full=Mannan-binding lectin serine protease 1; EC=3.4.21.-; AltName: Full=Complement factor MASP-3; AltName: Full=Complement-activating component of Ra-reactive factor; AltName: Full=Mannose-binding lectin-associated serine protease 1; Short=MASP-1; AltName: Full=Mannose-binding protein-associated serine protease; AltName: Full=Ra-reactive factor serine protease p100; Short=RaRF; AltName: Full=Serine protease 5; Contains: RecName: Full=Mannan-binding lectin serine protease 1 heavy chain; Contains: RecName: Full=Mannan-binding lectin serine protease 1 light chain; Flags: Precursor;+++[C9J1C7_HUMAN|Unreviewed]SubName: Full=Mannan-binding lectin serine protease 1 {ECO:0000313|Ensembl:ENSP00000412021}; Flags: Fragment;+++[C9JLU5_HUMAN|Unreviewed]SubName: Full=Mannan-binding lectin serine protease 1 {ECO:0000313|Ensembl:ENSP00000409047}; Flags: Fragment;+++[C9JMA2_HUMAN|Unreviewed]SubName: Full=Mannan-binding lectin serine protease 1 {ECO:0000313|Ensembl:ENSP00000376267}; Flags: Fragment;+++[F8W876_HUMAN|Unreviewed]SubName: Full=Mannan-binding lectin serine protease 1 {ECO:0000313|Ensembl:ENSP00000376262};"]
[56521,"'DNAJC12'",10,3,6,6.33333333333333,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005515///protein binding",null,"DnaJ heat shock protein family (Hsp40) member C12","[DJC12_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily C member 12; AltName: Full=J domain-containing protein 1;+++[Q6IAH1_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily C, member 12, isoform CRA_a {ECO:0000313|EMBL:EAW54255.1}; SubName: Full=JDP1 protein {ECO:0000313|EMBL:CAG33465.1}; SubName: Full=cDNA FLJ75242, highly similar to Homo sapiens DnaJ (Hsp40) homolog, subfamily C, member 12 (DNAJC12), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF82226.1};+++[S4R368_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 12 {ECO:0000313|Ensembl:ENSP00000473979};+++[S4R3E2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 12 {ECO:0000313|Ensembl:ENSP00000474215};+++[S4R3W0_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 12 {ECO:0000313|Ensembl:ENSP00000474804};"]
[56667,"'MUC13'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005796///Golgi lumen+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity","GO:0016266///O-glycan processing+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","mucin 13, cell surface associated","[MUC13_HUMAN|Reviewed]RecName: Full=Mucin-13; Short=MUC-13; AltName: Full=Down-regulated in colon cancer 1; Flags: Precursor;+++[C9IZG1_HUMAN|Unreviewed]SubName: Full=Mucin-13 {ECO:0000313|Ensembl:ENSP00000418660}; Flags: Fragment;"]
[56675,"'NRIP3'",51,42.14,61,51.38,{"$nulls":5},"GO:0005515///protein binding+++GO:0004190///aspartic-type endopeptidase activity","GO:0006508///proteolysis","nuclear receptor interacting protein 3","[NRIP3_HUMAN|Reviewed]RecName: Full=Nuclear receptor-interacting protein 3; AltName: Full=Sarcoma antigen NY-SAR-105;+++[B7Z3Y4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51629, highly similar to Nuclear receptor-interacting protein 3 {ECO:0000313|EMBL:BAH12370.1};+++[E9PIW3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000433845}; Flags: Fragment;+++[H0YCM9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000432002}; Flags: Fragment;+++[H0YEG7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000435785}; Flags: Fragment;"]
[5687,"'PSMA6'",514,535,552,533.666666666667,"03050///Proteasome",null,"M00337///Immunoproteasome+++M00340///Proteasome, 20S core particle",null,"GO:0005829///cytosol+++GO:0000932///P-body+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0030016///myofibril+++GO:0005654///nucleoplasm+++GO:0005839///proteasome core complex+++GO:0005844///polysome+++GO:0070062///extracellular exosome+++GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0030017///sarcomere","GO:0051059///NF-kappaB binding+++GO:0003723///RNA binding+++GO:0035639///purine ribonucleoside triphosphate binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0006508///proteolysis+++GO:0050727///regulation of inflammatory response+++GO:0010498///proteasomal protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0016579///protein deubiquitination+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process","proteasome subunit alpha 6","[PSA6_HUMAN|Reviewed]RecName: Full=Proteasome subunit alpha type-6; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=27 kDa prosomal protein; Short=PROS-27; Short=p27K; AltName: Full=Macropain iota chain; AltName: Full=Multicatalytic endopeptidase complex iota chain; AltName: Full=Proteasome iota chain;+++[A0A140VK44_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V295_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V2S7_HUMAN|Unreviewed]SubName: Full=Proteasome subunit alpha type-6 {ECO:0000313|Ensembl:ENSP00000450844};+++[G3V3I1_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V3U4_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V4S5_HUMAN|Unreviewed]SubName: Full=Proteasome subunit alpha type-6 {ECO:0000313|Ensembl:ENSP00000451958};+++[G3V5Z7_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[H0YJC4_HUMAN|Unreviewed]SubName: Full=Proteasome subunit alpha type-6 {ECO:0000313|Ensembl:ENSP00000451171}; Flags: Fragment;+++[Q9BZ93_HUMAN|Unreviewed]SubName: Full=Prosomal P27K protein {ECO:0000313|EMBL:AAG61139.1}; Flags: Fragment;"]
[56884,"'FSTL5'",0,1,1,0.666666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0032197///transposition, RNA-mediated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination","follistatin like 5","[FSTL5_HUMAN|Reviewed]RecName: Full=Follistatin-related protein 5; AltName: Full=Follistatin-like protein 5; Flags: Precursor;"]
[5690,"'PSMB2'",1433,1543,1430,1468.66666666667,"03050///Proteasome",null,"M00337///Immunoproteasome+++M00340///Proteasome, 20S core particle",null,"GO:0005839///proteasome core complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0019774///proteasome core complex, beta-subunit complex+++GO:0000502///proteasome complex+++GO:0005654///nucleoplasm","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0005515///protein binding","GO:0014070///response to organic cyclic compound+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0010243///response to organonitrogen compound+++GO:0006508///proteolysis+++GO:0010498///proteasomal protein catabolic process+++GO:0016032///viral process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination","proteasome subunit beta 2","[PSB2_HUMAN|Reviewed]RecName: Full=Proteasome subunit beta type-2; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=Macropain subunit C7-I; AltName: Full=Multicatalytic endopeptidase complex subunit C7-I; AltName: Full=Proteasome component C7-I;+++[A0A087WVV1_HUMAN|Unreviewed]SubName: Full=Proteasome subunit beta type-2 {ECO:0000313|Ensembl:ENSP00000479706};+++[A0A140VJS6_HUMAN|Unreviewed]RecName: Full=Proteasome subunit beta type {ECO:0000256|RuleBase:RU004203}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU004203};+++[B7Z478_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) subunit, beta type, 2, isoform CRA_b {ECO:0000313|EMBL:EAX07408.1}; SubName: Full=cDNA FLJ51890, highly similar to Proteasome subunit beta type 2 {ECO:0000313|EMBL:BAH12464.1};"]
[56919,"'DHX33'",353,254,291,299.333333333333,"04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0061702///inflammasome complex+++GO:0072559///NLRP3 inflammasome complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003729///mRNA binding+++GO:0005524///ATP binding+++GO:0033613///activating transcription factor binding+++GO:0005515///protein binding+++GO:0000182///rDNA binding+++GO:0003725///double-stranded RNA binding+++GO:0043023///ribosomal large subunit binding+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0003723///RNA binding","GO:0032481///positive regulation of type I interferon production+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:0043410///positive regulation of MAPK cascade+++GO:0006413///translational initiation+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","DEAH-box helicase 33","[DHX33_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DHX33 {ECO:0000305}; EC=3.6.4.13; AltName: Full=DEAH box protein 33;+++[B4DIS6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56443, highly similar to Putative ATP-dependent RNA helicase DHX33 {ECO:0000313|EMBL:BAG58588.1};+++[I3L0M5_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DHX33 {ECO:0000313|Ensembl:ENSP00000458203}; Flags: Fragment;+++[I3L1L6_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DHX33 {ECO:0000313|Ensembl:ENSP00000458925}; Flags: Fragment;+++[Q05BE5_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DHX33 {ECO:0000313|Ensembl:ENSP00000413779}; SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 33, isoform CRA_c {ECO:0000313|EMBL:EAW90333.1}; SubName: Full=DHX33 protein {ECO:0000313|EMBL:AAH50409.1};"]
[5694,"'PSMB6'",804,891,824,839.666666666667,"03050///Proteasome",null,"M00340///Proteasome, 20S core particle",null,"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0019774///proteasome core complex, beta-subunit complex+++GO:0000502///proteasome complex+++GO:0005839///proteasome core complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0004298///threonine-type endopeptidase activity+++GO:0045296///cadherin binding+++GO:0008233///peptidase activity+++GO:0004175///endopeptidase activity+++GO:0016787///hydrolase activity","GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016032///viral process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0010498///proteasomal protein catabolic process+++GO:0006508///proteolysis+++GO:0043687///post-translational protein modification","proteasome subunit beta 6","[PSB6_HUMAN|Reviewed]RecName: Full=Proteasome subunit beta type-6; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=Macropain delta chain; AltName: Full=Multicatalytic endopeptidase complex delta chain; AltName: Full=Proteasome delta chain; AltName: Full=Proteasome subunit Y; Flags: Precursor;+++[A0A087X2I4_HUMAN|Unreviewed]RecName: Full=Proteasome subunit beta type {ECO:0000256|RuleBase:RU004203}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU004203};+++[I3L3X7_HUMAN|Unreviewed]SubName: Full=Proteasome subunit beta type-6 {ECO:0000313|Ensembl:ENSP00000460811}; Flags: Fragment;+++[Q6IAT9_HUMAN|Unreviewed]RecName: Full=Proteasome subunit beta type {ECO:0000256|RuleBase:RU004203}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU004203};"]
[56954,"'NIT2'",156,179,149,161.333333333333,"00250///Alanine, aspartate and glutamate metabolism",null,null,"R00269///2-oxoglutaramate amidohydrolase   2-Oxoglutaramate + H2O <=> 2-Oxoglutarate + Ammonia+++R00348///2-oxosuccinamate amidohydrolase   2-Oxosuccinamate + H2O <=> Oxaloacetate + Ammonia","GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:1904724///tertiary granule lumen+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0035580///specific granule lumen","GO:0016787///hydrolase activity+++GO:0050152///omega-amidase activity","GO:0006541///glutamine metabolic process+++GO:0006107///oxaloacetate metabolic process+++GO:0006528///asparagine metabolic process+++GO:0043312///neutrophil degranulation+++GO:0006807///nitrogen compound metabolic process","nitrilase family member 2","[NIT2_HUMAN|Reviewed]RecName: Full=Omega-amidase NIT2; EC=3.5.1.3; AltName: Full=Nitrilase homolog 2;+++[F8WF58_HUMAN|Unreviewed]SubName: Full=Omega-amidase NIT2 {ECO:0000313|Ensembl:ENSP00000419239};+++[F8WF70_HUMAN|Unreviewed]SubName: Full=Omega-amidase NIT2 {ECO:0000313|Ensembl:ENSP00000419157};+++[H7C579_HUMAN|Unreviewed]SubName: Full=Omega-amidase NIT2 {ECO:0000313|Ensembl:ENSP00000419189}; Flags: Fragment;+++[V9HW91_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 8a {ECO:0000313|EMBL:ACI46018.1};"]
[56983,"'POGLUT1'",423,362,398,394.333333333333,"00514///Other types of O-glycan biosynthesis","H00593///Limb-girdle muscular dystrophy (LGMD)",null,"R09315///UDP-D-glucose + [Protein]-L-serine <=> UDP + G13051","GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0030158///protein xylosyltransferase activity+++GO:0046527///glucosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0035251///UDP-glucosyltransferase activity+++GO:0035252///UDP-xylosyltransferase activity","GO:0007369///gastrulation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0006493///protein O-linked glycosylation+++GO:0010470///regulation of gastrulation+++GO:0007275///multicellular organism development+++GO:0048318///axial mesoderm development+++GO:0006486///protein glycosylation+++GO:0008593///regulation of Notch signaling pathway+++GO:0001756///somitogenesis+++GO:0060537///muscle tissue development+++GO:0048339///paraxial mesoderm development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0072358///cardiovascular system development","protein O-glucosyltransferase 1","[PGLT1_HUMAN|Reviewed]RecName: Full=Protein O-glucosyltransferase 1 {ECO:0000305}; EC=2.4.1.- {ECO:0000269|PubMed:21490058, ECO:0000269|PubMed:21949356}; AltName: Full=CAP10-like 46 kDa protein {ECO:0000303|PubMed:16524674}; Short=hCLP46 {ECO:0000303|PubMed:16524674}; AltName: Full=KTEL motif-containing protein 1; AltName: Full=Myelodysplastic syndromes relative protein; AltName: Full=O-glucosyltransferase Rumi homolog {ECO:0000303|PubMed:21490058}; Short=hRumi {ECO:0000303|PubMed:21490058}; AltName: Full=Protein O-xylosyltransferase POGLUT1 {ECO:0000305}; EC=2.4.2.26 {ECO:0000269|PubMed:21081508, ECO:0000269|PubMed:28775322}; Flags: Precursor;+++[B4DJ97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53005, highly similar to CAP10-like 46 kDa protein {ECO:0000313|EMBL:BAG58759.1};+++[B4DVA9_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419288}; SubName: Full=cDNA FLJ53000, highly similar to CAP10-like 46 kDa protein {ECO:0000313|EMBL:BAG62621.1};+++[F8WDC4_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000420594};+++[F8WEW4_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419876};+++[H7C5H0_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419865}; Flags: Fragment;"]
[570,"'BAAT'",0,1,0,0.333333333333333,"00120///Primary bile acid biosynthesis+++04976///Bile secretion+++00430///Taurine and hypotaurine metabolism+++01040///Biosynthesis of unsaturated fatty acids+++04146///Peroxisome+++01100///Metabolic pathways","H01935///Familial hypercholanemia","M00106///Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate","R08745///3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase; chenodeoxycholoyl-CoA:taurine   Chenodeoxycholoyl-CoA + Taurine <=> Taurochenodeoxycholate + CoA+++R03720///Choloyl-CoA:glycine N-choloyltransferase   Choloyl-CoA + Taurine <=> CoA + Taurocholate+++R08744///3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:glycine N-choloyltransferase; chenodeoxycholoyl-CoA:glycine   Chenodeoxycholoyl-CoA + Glycine <=> Glycochenodeoxycholate + CoA+++R03718///Choloyl-CoA:glycine N-choloyltransferase   Choloyl-CoA + Glycine <=> CoA + Glycocholate","GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix+++GO:0005829///cytosol","GO:0052689///carboxylic ester hydrolase activity+++GO:0052816///long-chain acyl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0052815///medium-chain acyl-CoA hydrolase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0052817///very long chain acyl-CoA hydrolase activity+++GO:0016410///N-acyltransferase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0005102///signaling receptor binding+++GO:0047963///glycine N-choloyltransferase activity+++GO:0016790///thiolester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity","GO:0001889///liver development+++GO:0006631///fatty acid metabolic process+++GO:0019530///taurine metabolic process+++GO:0006625///protein targeting to peroxisome+++GO:0006629///lipid metabolic process+++GO:0006544///glycine metabolic process+++GO:0031100///animal organ regeneration+++GO:0002152///bile acid conjugation+++GO:0008206///bile acid metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0006637///acyl-CoA metabolic process","bile acid-CoA:amino acid N-acyltransferase","[BAAT_HUMAN|Reviewed]RecName: Full=Bile acid-CoA:amino acid N-acyltransferase {ECO:0000303|PubMed:8034703}; Short=BACAT {ECO:0000303|PubMed:12810727}; Short=BAT {ECO:0000303|PubMed:8034703}; EC=2.3.1.65 {ECO:0000269|PubMed:12810727, ECO:0000269|PubMed:8034703}; AltName: Full=Glycine N-choloyltransferase; AltName: Full=Long-chain fatty-acyl-CoA hydrolase {ECO:0000303|PubMed:12810727}; EC=3.1.2.2 {ECO:0000269|PubMed:12810727};+++[A0A024R149_HUMAN|Unreviewed]SubName: Full=Bile acid Coenzyme A: amino acid N-acyltransferase (Glycine N-choloyltransferase), isoform CRA_b {ECO:0000313|EMBL:EAW58946.1};+++[A0A024R155_HUMAN|Unreviewed]SubName: Full=Bile acid Coenzyme A: amino acid N-acyltransferase (Glycine N-choloyltransferase), isoform CRA_a {ECO:0000313|EMBL:EAW58945.1};"]
[57038,"'RARS2'",619.97,535,591,581.99,"00970///Aminoacyl-tRNA biosynthesis","H00679///Hypomyelinating leukodystrophy+++H00897///Pontocerebellar hypoplasia","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03646///L-Arginine:tRNA(Arg) ligase (AMP-forming)   ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)","GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004814///arginine-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000166///nucleotide binding","GO:0006420///arginyl-tRNA aminoacylation+++GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0006418///tRNA aminoacylation for protein translation","arginyl-tRNA synthetase 2, mitochondrial","[SYRM_HUMAN|Reviewed]RecName: Full=Probable arginine--tRNA ligase, mitochondrial; EC=6.1.1.19; AltName: Full=Arginyl-tRNA synthetase; Short=ArgRS; Flags: Precursor;+++[H0UI22_HUMAN|Unreviewed]SubName: Full=Arginyl-tRNA synthetase-like, isoform CRA_e {ECO:0000313|EMBL:EAW48590.1};+++[H0Y450_HUMAN|Unreviewed]SubName: Full=Probable arginine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000389656}; Flags: Fragment;"]
[57085,"'AGTRAP'",1040,1168,1232,1146.66666666667,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005938///cell cortex","GO:0004945///angiotensin type II receptor activity+++GO:0005515///protein binding","GO:0038166///angiotensin-activated signaling pathway+++GO:0001666///response to hypoxia+++GO:0008217///regulation of blood pressure","angiotensin II receptor associated protein","[ATRAP_HUMAN|Reviewed]RecName: Full=Type-1 angiotensin II receptor-associated protein; AltName: Full=AT1 receptor-associated protein;+++[D6RB40_HUMAN|Unreviewed]SubName: Full=Type-1 angiotensin II receptor-associated protein {ECO:0000313|Ensembl:ENSP00000424455};+++[D6RBK6_HUMAN|Unreviewed]SubName: Full=Type-1 angiotensin II receptor-associated protein {ECO:0000313|Ensembl:ENSP00000422647};+++[X6R9H3_HUMAN|Unreviewed]SubName: Full=Type-1 angiotensin II receptor-associated protein {ECO:0000313|Ensembl:ENSP00000365814};"]
[57109,"'REXO4'",478,530,469,492.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016607///nuclear speck","GO:0003676///nucleic acid binding+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0008408///3'-5' exonuclease activity+++GO:0003723///RNA binding+++GO:0004518///nuclease activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0006364///rRNA processing+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","REX4 homolog, 3'-5' exonuclease","[REXO4_HUMAN|Reviewed]RecName: Full=RNA exonuclease 4; EC=3.1.-.-; AltName: Full=Exonuclease XPMC2; AltName: Full=Prevents mitotic catastrophe 2 protein homolog; Short=hPMC2;+++[A0A0C4DG22_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 4 {ECO:0000313|Ensembl:ENSP00000391534}; Flags: Fragment;+++[A0A0C4DG31_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 4 {ECO:0000313|Ensembl:ENSP00000394229}; Flags: Fragment;+++[B4DJ95_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55848, highly similar to RNA exonuclease 4 {ECO:0000313|EMBL:BAG58757.1};+++[B4E331_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50372, highly similar to RNA exonuclease 4 {ECO:0000313|EMBL:BAG65343.1}; SubName: Full=cDNA, FLJ78803, highly similar to RNA exonuclease 4 {ECO:0000313|EMBL:BAH14275.1};"]
[57125,"'PLXDC1'",10,8,12,10,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005923///bicellular tight junction+++GO:0030425///dendrite+++GO:0043235///receptor complex+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body","GO:0005515///protein binding","GO:0001525///angiogenesis+++GO:0021510///spinal cord development","plexin domain containing 1","[PLDX1_HUMAN|Reviewed]RecName: Full=Plexin domain-containing protein 1; AltName: Full=Tumor endothelial marker 3; AltName: Full=Tumor endothelial marker 7; Flags: Precursor;+++[A0A172Q3A1_HUMAN|Unreviewed]SubName: Full=Tumor endothelial marker 7 {ECO:0000313|EMBL:AND76659.1}; Flags: Fragment;+++[B4E173_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58221, highly similar to Plexin domain-containing protein 1 {ECO:0000313|EMBL:BAG64685.1};+++[C9JCL2_HUMAN|Unreviewed]SubName: Full=Plexin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000416819}; Flags: Fragment;+++[C9JWQ3_HUMAN|Unreviewed]SubName: Full=Plexin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000393227}; Flags: Fragment;+++[J3KS04_HUMAN|Unreviewed]SubName: Full=Plexin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000462241};+++[J3QR40_HUMAN|Unreviewed]SubName: Full=Plexin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000464029}; Flags: Fragment;+++[J3QRR7_HUMAN|Unreviewed]SubName: Full=Plexin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000464353}; Flags: Fragment;+++[L8EA73_HUMAN|Unreviewed]SubName: Full=Alternative protein PLXDC1 {ECO:0000313|EMBL:CCQ43636.1};"]
[57150,"'SMIM8'",26,22,31,26.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"small integral membrane protein 8","[SMIM8_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 8;+++[V9GYF9_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 8 {ECO:0000313|Ensembl:ENSP00000476709};+++[V9GYL2_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 8 {ECO:0000313|Ensembl:ENSP00000476881};"]
[57167,"'SALL4'",3,6,1,3.33333333333333,null,"H00573///Townes-Brocks syndrome+++H01114///Ocular coloboma+++H00634///Duane-radial ray syndrome and IVIC syndrome",null,null,"GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding","GO:0007507///heart development+++GO:0003281///ventricular septum development+++GO:0001701///in utero embryonic development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035019///somatic stem cell population maintenance+++GO:0021915///neural tube development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001843///neural tube closure+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0001833///inner cell mass cell proliferation+++GO:0019827///stem cell population maintenance+++GO:0009888///tissue development+++GO:0030326///embryonic limb morphogenesis","spalt like transcription factor 4","[SALL4_HUMAN|Reviewed]RecName: Full=Sal-like protein 4; AltName: Full=Zinc finger protein 797; AltName: Full=Zinc finger protein SALL4;+++[Q6Y8G5_HUMAN|Unreviewed]SubName: Full=SALL4C {ECO:0000313|EMBL:AAO16567.1}; SubName: Full=Sal-like protein 4 {ECO:0000313|Ensembl:ENSP00000360594};"]
[57192,"'MCOLN1'",753,803,809,788.333333333333,"04142///Lysosome","H00144///Mucolipidosis IV",null,null,"GO:0043235///receptor complex+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005765///lysosomal membrane+++GO:0005887///integral component of plasma membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0031902///late endosome membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005770///late endosome+++GO:0042995///cell projection+++GO:0010008///endosome membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0001891///phagocytic cup+++GO:0031410///cytoplasmic vesicle","GO:0005261///cation channel activity+++GO:0008289///lipid binding+++GO:0097682///intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity+++GO:0005381///iron ion transmembrane transporter activity+++GO:0005262///calcium channel activity+++GO:0099604///ligand-gated calcium channel activity+++GO:0072345///NAADP-sensitive calcium-release channel activity+++GO:0005515///protein binding","GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0071467///cellular response to pH+++GO:0051289///protein homotetramerization+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0033572///transferrin transport+++GO:0034220///ion transmembrane transport+++GO:0006816///calcium ion transport+++GO:0071277///cellular response to calcium ion+++GO:0034755///iron ion transmembrane transport+++GO:0070588///calcium ion transmembrane transport+++GO:0002376///immune system process+++GO:0097352///autophagosome maturation+++GO:0019722///calcium-mediated signaling+++GO:0002250///adaptive immune response+++GO:0098655///cation transmembrane transport","mucolipin 1","[MCLN1_HUMAN|Reviewed]RecName: Full=Mucolipin-1 {ECO:0000303|PubMed:12459486}; Short=ML1; AltName: Full=MG-2; AltName: Full=Mucolipidin {ECO:0000303|PubMed:11013137}; AltName: Full=Transient receptor potential channel mucolipin 1; Short=TRPML1 {ECO:0000303|PubMed:28112729};+++[M0QXD0_HUMAN|Unreviewed]SubName: Full=Mucolipin-1 {ECO:0000313|Ensembl:ENSP00000469074}; Flags: Fragment;+++[M0R1X7_HUMAN|Unreviewed]SubName: Full=Mucolipin-1 {ECO:0000313|Ensembl:ENSP00000472176}; Flags: Fragment;"]
[57213,"'SPRYD7'",178.62,167.28,148,164.633333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0005515///protein binding",null,"SPRY domain containing 7","[SPRY7_HUMAN|Reviewed]RecName: Full=SPRY domain-containing protein 7; AltName: Full=Chronic lymphocytic leukemia deletion region gene 6 protein; Short=CLL deletion region gene 6 protein;+++[A0A024RDT6_HUMAN|Unreviewed]SubName: Full=Chromosome 13 open reading frame 1, isoform CRA_a {ECO:0000313|EMBL:EAX08842.1};"]
[5725,"'PTBP1'",6130,5937,5837,5968,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0036002///pre-mRNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008187///poly-pyrimidine tract binding+++GO:0003723///RNA binding","GO:0035307///positive regulation of protein dephosphorylation+++GO:0033119///negative regulation of RNA splicing+++GO:0051148///negative regulation of muscle cell differentiation+++GO:0016070///RNA metabolic process+++GO:0008380///RNA splicing+++GO:0075522///IRES-dependent viral translational initiation+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0048025///negative regulation of mRNA splicing, via spliceosome","polypyrimidine tract binding protein 1","[PTBP1_HUMAN|Reviewed]RecName: Full=Polypyrimidine tract-binding protein 1; Short=PTB; AltName: Full=57 kDa RNA-binding protein PPTB-1; AltName: Full=Heterogeneous nuclear ribonucleoprotein I; Short=hnRNP I;+++[A0A087WTS6_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000478097}; Flags: Fragment;+++[A0A087WU68_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000478414}; Flags: Fragment;+++[A0A087WUW5_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000478974}; Flags: Fragment;+++[A0A0D9SF20_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract binding protein 1, isoform CRA_e {ECO:0000313|EMBL:EAW61156.1}; SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000486218};+++[A0A0U1RRM4_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000489604};+++[A6NLN1_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract binding protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW61153.1}; SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000342332};+++[K7EK45_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000465451}; Flags: Fragment;+++[K7EKJ7_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000465652}; Flags: Fragment;+++[K7EKX4_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000465825}; Flags: Fragment;+++[K7ELW5_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000466250}; Flags: Fragment;+++[K7ES59_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 1 {ECO:0000313|Ensembl:ENSP00000468565}; Flags: Fragment;"]
[57325,"'KAT14'",419.34,378.99,403.61,400.646666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0030274///LIM domain binding+++GO:0004402///histone acetyltransferase activity","GO:0043966///histone H3 acetylation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016573///histone acetylation","lysine acetyltransferase 14","[CSR2B_HUMAN|Reviewed]RecName: Full=Cysteine-rich protein 2-binding protein; Short=CSRP2-binding protein; AltName: Full=ADA2A-containing complex subunit 2; Short=ATAC2; AltName: Full=CRP2-binding partner; Short=CRP2BP; AltName: Full=Lysine acetyltransferase 14 {ECO:0000312|HGNC:HGNC:15904};+++[A0A075B6H4_HUMAN|Unreviewed]SubName: Full=Cysteine-rich protein 2-binding protein {ECO:0000313|Ensembl:ENSP00000366909};+++[D6RAU4_HUMAN|Unreviewed]SubName: Full=Cysteine-rich protein 2-binding protein {ECO:0000313|Ensembl:ENSP00000424752}; Flags: Fragment;"]
[57404,"'CYP20A1'",275.14,308.85,320,301.33,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005506///iron ion binding+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0004497///monooxygenase activity","GO:0055114///oxidation-reduction process","cytochrome P450 family 20 subfamily A member 1","[CP20A_HUMAN|Reviewed]RecName: Full=Cytochrome P450 20A1; EC=1.14.-.-;+++[C9J8K7_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 20A1 {ECO:0000313|Ensembl:ENSP00000411341}; Flags: Fragment;+++[E9PHG5_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 20A1 {ECO:0000313|Ensembl:ENSP00000407860};+++[F2Z3K6_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 20A1 {ECO:0000313|Ensembl:ENSP00000398046};+++[F8WBE2_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 20A1 {ECO:0000313|Ensembl:ENSP00000414831};+++[Q53RS5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CYP20A1 {ECO:0000313|EMBL:AAY14934.1}; Flags: Fragment;+++[Q567U3_HUMAN|Unreviewed]SubName: Full=CYP20A1 protein {ECO:0000313|EMBL:AAH93022.1}; Flags: Fragment;+++[Q8WZ13_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 20A1 {ECO:0000313|Ensembl:ENSP00000482757};"]
[57415,"'C3orf14'",77,29,38,48,{"$nulls":7},"chromosome 3 open reading frame 14","[CC014_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C3orf14;+++[A0A024R330_HUMAN|Unreviewed]SubName: Full=Chromosome 3 open reading frame 14, isoform CRA_a {ECO:0000313|EMBL:EAW65401.1};+++[C9JY17_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C3orf14 {ECO:0000313|Ensembl:ENSP00000419937}; Flags: Fragment;"]
[5746,"'PTH2R'",0,0,2,0.666666666666667,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0008528///G protein-coupled peptide receptor activity+++GO:0017046///peptide hormone binding+++GO:0004991///parathyroid hormone receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0007165///signal transduction","parathyroid hormone 2 receptor","[PTH2R_HUMAN|Reviewed]RecName: Full=Parathyroid hormone 2 receptor; Short=PTH2 receptor; Flags: Precursor;+++[B4DFN8_HUMAN|Unreviewed]SubName: Full=Parathyroid hormone 2 receptor {ECO:0000313|Ensembl:ENSP00000482485}; SubName: Full=cDNA FLJ60238, highly similar to Parathyroid hormone receptor {ECO:0000313|EMBL:BAG57499.1};+++[H7C0B0_HUMAN|Unreviewed]SubName: Full=Parathyroid hormone 2 receptor {ECO:0000313|Ensembl:ENSP00000393930}; Flags: Fragment;+++[Q53SF6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PTHR2 {ECO:0000313|EMBL:AAY15091.1}; Flags: Fragment;+++[Q53T35_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PTHR2 {ECO:0000313|EMBL:AAY14871.1}; Flags: Fragment;"]
[57469,"'PNMA8B'",129,129,127,128.333333333333,{"$nulls":7},"PNMA family member 8B","[PNM8B_HUMAN|Reviewed]RecName: Full=Paraneoplastic antigen-like protein 8B; AltName: Full=PNMA-like protein 2;"]
[57496,"'MRTFB'",611,327,479,472.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0045296///cadherin binding+++GO:0003779///actin binding+++GO:0003713///transcription coactivator activity","GO:0051145///smooth muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0045844///positive regulation of striated muscle tissue development","myocardin related transcription factor B","[MRTFB_HUMAN|Reviewed]RecName: Full=Myocardin-related transcription factor B {ECO:0000305}; Short=MRTF-B {ECO:0000305}; AltName: Full=MKL/myocardin-like protein 2; AltName: Full=Megakaryoblastic leukemia 2 {ECO:0000303|PubMed:14565952};+++[A1L1A9_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[I3L0U1_HUMAN|Unreviewed]SubName: Full=Myocardin-related transcription factor B {ECO:0000313|Ensembl:ENSP00000458340}; Flags: Fragment;+++[I3L2A0_HUMAN|Unreviewed]SubName: Full=Myocardin-related transcription factor B {ECO:0000313|Ensembl:ENSP00000459518}; Flags: Fragment;+++[I3L2S3_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};+++[I3L3Z7_HUMAN|Unreviewed]SubName: Full=Myocardin-related transcription factor B {ECO:0000313|Ensembl:ENSP00000460848}; Flags: Fragment;+++[Q05BP1_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;"]
[57509,"'MTUS1'",215,150,230,198.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005819///spindle+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005815///microtubule organizing center+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005874///microtubule+++GO:0016020///membrane","GO:0008017///microtubule binding","GO:0010758///regulation of macrophage chemotaxis","microtubule associated scaffold protein 1","[MTUS1_HUMAN|Reviewed]RecName: Full=Microtubule-associated tumor suppressor 1; AltName: Full=AT2 receptor-binding protein; AltName: Full=Angiotensin-II type 2 receptor-interacting protein; AltName: Full=Mitochondrial tumor suppressor 1;+++[A0A0U1RQI2_HUMAN|Unreviewed]SubName: Full=Microtubule-associated tumor suppressor 1 {ECO:0000313|Ensembl:ENSP00000489015};+++[H0YC63_HUMAN|Unreviewed]SubName: Full=Microtubule-associated tumor suppressor 1 {ECO:0000313|Ensembl:ENSP00000431016}; Flags: Fragment;"]
[57533,"'TBC1D14'",1219,877,1294,1130,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005776///autophagosome+++GO:0055037///recycling endosome+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0019901///protein kinase binding+++GO:0017137///Rab GTPase binding","GO:0010507///negative regulation of autophagy+++GO:0071955///recycling endosome to Golgi transport+++GO:2000785///regulation of autophagosome assembly+++GO:0090630///activation of GTPase activity+++GO:1902017///regulation of cilium assembly+++GO:0006886///intracellular protein transport","TBC1 domain family member 14","[TBC14_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 14;+++[B9A071_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 14 {ECO:0000313|Ensembl:ENSP00000386343};+++[C9J541_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 14 {ECO:0000313|Ensembl:ENSP00000411760}; Flags: Fragment;+++[C9JP26_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 14 {ECO:0000313|Ensembl:ENSP00000414951}; Flags: Fragment;+++[F5GXK4_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 14 {ECO:0000313|Ensembl:ENSP00000405875};+++[H7BZD7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 14 {ECO:0000313|Ensembl:ENSP00000389082}; Flags: Fragment;"]
[57546,"'PDP2'",310.54,285.09,330.03,308.553333333333,null,"H00072///Pyruvate dehydrogenase complex deficiency+++H01996///Pyruvate dehydrogenase phosphatase deficiency",null,null,"GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity+++GO:0004741///[pyruvate dehydrogenase (lipoamide)] phosphatase activity+++GO:0003824///catalytic activity+++GO:0046872///metal ion binding+++GO:0043169///cation binding","GO:0006470///protein dephosphorylation+++GO:0010510///regulation of acetyl-CoA biosynthetic process from pyruvate","pyruvate dehyrogenase phosphatase catalytic subunit 2","[PDP2_HUMAN|Reviewed]RecName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial; Short=PDP 2; EC=3.1.3.43; AltName: Full=Pyruvate dehydrogenase phosphatase catalytic subunit 2; Short=PDPC 2; Flags: Precursor;+++[H3BQX2_HUMAN|Unreviewed]SubName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000455975}; Flags: Fragment;+++[H3BRB7_HUMAN|Unreviewed]SubName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000456171}; Flags: Fragment;+++[H3BSA5_HUMAN|Unreviewed]SubName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000456611}; Flags: Fragment;+++[H3BTU5_HUMAN|Unreviewed]SubName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000457331}; Flags: Fragment;+++[H3BV50_HUMAN|Unreviewed]SubName: Full=[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000457951}; Flags: Fragment;"]
[5757,"'PTMA'",13398.98,13812.11,12214.55,13141.88,"05169///Epstein-Barr virus infection",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0033613///activating transcription factor binding+++GO:0042393///histone binding","GO:0006351///transcription, DNA-templated+++GO:0043486///histone exchange","prothymosin alpha","[PTMA_HUMAN|Reviewed]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[Q53S24_HUMAN|Unreviewed]SubName: Full=Prothymosin, alpha {ECO:0000313|EMBL:AAH03510.1}; SubName: Full=Prothymosin, alpha (Gene sequence 28) variant {ECO:0000313|EMBL:BAD97325.1}; SubName: Full=cDNA, FLJ94794, highly similar to Homo sapiens prothymosin, alpha (gene sequence 28) (PTMA), mRNA {ECO:0000313|EMBL:BAG36799.1};"]
[57584,"'ARHGAP21'",3211,2578,2852,2880.33333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0051684///maintenance of Golgi location+++GO:0007030///Golgi organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0051683///establishment of Golgi localization+++GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0072384///organelle transport along microtubule+++GO:0007010///cytoskeleton organization","Rho GTPase activating protein 21","[RHG21_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 21; AltName: Full=Rho GTPase-activating protein 10; AltName: Full=Rho-type GTPase-activating protein 21;+++[A0A087WW76_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000480005};+++[A0A1B0GTZ9_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000489905}; Flags: Fragment;+++[A0A1B0GV73_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000490396};+++[A0A1B0GW11_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000490730}; Flags: Fragment;+++[A0A2X0SF83_HUMAN|Unreviewed]SubName: Full=ARHGAP21 {ECO:0000313|EMBL:SPT35692.1}; Flags: Fragment;+++[E7ESW5_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000405018}; Flags: Fragment;+++[F8W9U9_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000365592};+++[H0Y468_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000389940}; Flags: Fragment;+++[H0Y5T2_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000400566}; Flags: Fragment;+++[J3JSM9_HUMAN|Unreviewed]SubName: Full=ARHGAP21 protein {ECO:0000313|EMBL:AAI18916.1};+++[L8EB25_HUMAN|Unreviewed]SubName: Full=Alternative protein ARHGAP21 {ECO:0000313|EMBL:CCQ43648.1};+++[Q5JSD8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 21 {ECO:0000313|Ensembl:ENSP00000402761}; Flags: Fragment;"]
[57605,"'PITPNM2'",187,185,206,192.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0005829///cytosol+++GO:0044297///cell body+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005509///calcium ion binding+++GO:0035091///phosphatidylinositol binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0008525///phosphatidylcholine transporter activity+++GO:0046872///metal ion binding+++GO:0031210///phosphatidylcholine binding+++GO:0008289///lipid binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0005548///phospholipid transporter activity","GO:0048015///phosphatidylinositol-mediated signaling+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0015914///phospholipid transport","phosphatidylinositol transfer protein membrane associated 2","[PITM2_HUMAN|Reviewed]RecName: Full=Membrane-associated phosphatidylinositol transfer protein 2; AltName: Full=Phosphatidylinositol transfer protein, membrane-associated 2; Short=PITPnm 2; AltName: Full=Pyk2 N-terminal domain-interacting receptor 3; Short=NIR-3;+++[A5D8U3_HUMAN|Unreviewed]SubName: Full=PITPNM2 protein {ECO:0000313|EMBL:AAI41814.1};+++[F5H361_HUMAN|Unreviewed]SubName: Full=Membrane-associated phosphatidylinositol transfer protein 2 {ECO:0000313|Ensembl:ENSP00000445399}; Flags: Fragment;+++[F5H664_HUMAN|Unreviewed]SubName: Full=Membrane-associated phosphatidylinositol transfer protein 2 {ECO:0000313|Ensembl:ENSP00000437869}; Flags: Fragment;+++[L8EB28_HUMAN|Unreviewed]SubName: Full=Alternative protein PITPNM2 {ECO:0000313|EMBL:CCQ43653.1};+++[Q9UF51_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434P0917 {ECO:0000313|EMBL:CAB63741.1}; Flags: Fragment;+++[S4R414_HUMAN|Unreviewed]SubName: Full=Membrane-associated phosphatidylinositol transfer protein 2 {ECO:0000313|Ensembl:ENSP00000474962};"]
[57623,"'ZFAT'",409,430,422,420.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0002244///hematopoietic progenitor cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060712///spongiotrophoblast layer development+++GO:0030097///hemopoiesis","zinc finger and AT-hook domain containing","[ZFAT_HUMAN|Reviewed]RecName: Full=Zinc finger protein ZFAT; AltName: Full=Zinc finger gene in AITD susceptibility region; AltName: Full=Zinc finger protein 406;+++[B7Z6H1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53576, highly similar to Zinc finger protein 406 {ECO:0000313|EMBL:BAH13257.1};+++[E5RGN2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000429983}; Flags: Fragment;+++[E5RH37_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000429930};+++[E5RJL9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000429050};+++[E5RJT2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000428192}; Flags: Fragment;+++[E9PBN4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000427879};+++[F8W7M8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000394501};+++[H0YBJ1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000429600}; Flags: Fragment;+++[H0YC51_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFAT {ECO:0000313|Ensembl:ENSP00000430924}; Flags: Fragment;+++[Q4KMQ4_HUMAN|Unreviewed]SubName: Full=ZFAT protein {ECO:0000313|EMBL:AAH98405.1}; Flags: Fragment;+++[Q6PJQ2_HUMAN|Unreviewed]SubName: Full=ZFAT protein {ECO:0000313|EMBL:AAH12989.1}; Flags: Fragment;"]
[57648,"'KIAA1522'",2904,2720,2933,2852.33333333333,{"$nulls":6},"GO:0030154///cell differentiation","KIAA1522","[K1522_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA1522;"]
[57674,"'RNF213'",1668,1251,1660,1526.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01396///Moyamoya disease",null,null,"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0016887///ATPase activity+++GO:0016787///hydrolase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0002040///sprouting angiogenesis+++GO:0001525///angiogenesis+++GO:0051260///protein homooligomerization+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination+++GO:2000051///negative regulation of non-canonical Wnt signaling pathway+++GO:0051865///protein autoubiquitination+++GO:0016567///protein ubiquitination","ring finger protein 213","[RN213_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF213 {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:21799892}; EC=3.6.4.- {ECO:0000269|PubMed:21799892}; AltName: Full=ALK lymphoma oligomerization partner on chromosome 17 {ECO:0000303|PubMed:12112524}; AltName: Full=Mysterin {ECO:0000303|PubMed:26126547}; AltName: Full=RING finger protein 213 {ECO:0000305}; AltName: Full=RING-type E3 ubiquitin transferase RNF213 {ECO:0000305};+++[A0A024R8W2_HUMAN|Unreviewed]SubName: Full=Chromosome 17 open reading frame 27, isoform CRA_a {ECO:0000313|EMBL:EAW89600.1};+++[A0A0A0MTC1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF213 {ECO:0000313|Ensembl:ENSP00000425956};+++[A0A0A0MTR7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF213 {ECO:0000313|Ensembl:ENSP00000464087};+++[I3L3H9_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF213 {ECO:0000313|Ensembl:ENSP00000460462}; Flags: Fragment;"]
[57693,"'ZNF317'",540,294,408,414,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 317","[ZN317_HUMAN|Reviewed]RecName: Full=Zinc finger protein 317;+++[A0A024R775_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 317, isoform CRA_a {ECO:0000313|EMBL:EAW84013.1};+++[A0A024R7B1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 317, isoform CRA_b {ECO:0000313|EMBL:EAW84014.1};+++[K7EKT9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 317 {ECO:0000313|Ensembl:ENSP00000465780};+++[K7ERD6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 317 {ECO:0000313|Ensembl:ENSP00000468213}; Flags: Fragment;"]
[57696,"'DDX55'",269,197,190,218.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity","GO:0010501///RNA secondary structure unwinding","DEAD-box helicase 55","[DDX55_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX55; EC=3.6.4.13; AltName: Full=DEAD box protein 55;+++[A0A024RBS0_HUMAN|Unreviewed]RecName: Full=RNA helicase {ECO:0000256|SAAS:SAAS00892872}; EC=3.6.4.13 {ECO:0000256|SAAS:SAAS00892872};+++[E7EX41_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX55 {ECO:0000313|Ensembl:ENSP00000346244};+++[F5H2I2_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX55 {ECO:0000313|Ensembl:ENSP00000446255};+++[F5H5U2_HUMAN|Unreviewed]RecName: Full=RNA helicase {ECO:0000256|SAAS:SAAS00892872}; EC=3.6.4.13 {ECO:0000256|SAAS:SAAS00892872};+++[F5H735_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX55 {ECO:0000313|Ensembl:ENSP00000442823};"]
[57731,"'SPTBN4'",104,78,107,96.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00063///Spinocerebellar ataxia (SCA)+++H00230///Hereditary spherocytosis (SPH)+++H00231///Hereditary elliptocytosis (HE)+++H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0005938///cell cortex+++GO:0070852///cell body fiber+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0043203///axon hillock+++GO:0033270///paranode region of axon+++GO:0016605///PML body+++GO:0043194///axon initial segment+++GO:0005912///adherens junction+++GO:0070062///extracellular exosome+++GO:0008091///spectrin+++GO:0030424///axon+++GO:0033268///node of Ranvier+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0014704///intercalated disc+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005543///phospholipid binding+++GO:0030506///ankyrin binding+++GO:0030507///spectrin binding","GO:0021952///central nervous system projection neuron axonogenesis+++GO:0007605///sensory perception of sound+++GO:0045162///clustering of voltage-gated sodium channels+++GO:0072659///protein localization to plasma membrane+++GO:0007010///cytoskeleton organization+++GO:0002028///regulation of sodium ion transport+++GO:0007409///axonogenesis+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009566///fertilization+++GO:0034613///cellular protein localization+++GO:0010459///negative regulation of heart rate+++GO:0007628///adult walking behavior+++GO:0007411///axon guidance+++GO:0022414///reproductive process+++GO:0061337///cardiac conduction+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0016192///vesicle-mediated transport+++GO:0007016///cytoskeletal anchoring at plasma membrane+++GO:0051693///actin filament capping+++GO:0030534///adult behavior+++GO:0040018///positive regulation of multicellular organism growth+++GO:0019226///transmission of nerve impulse+++GO:0000165///MAPK cascade","spectrin beta, non-erythrocytic 4","[SPTN4_HUMAN|Reviewed]RecName: Full=Spectrin beta chain, non-erythrocytic 4; AltName: Full=Beta-IV spectrin; AltName: Full=Spectrin, non-erythroid beta chain 3;+++[A0A024R0N6_HUMAN|Unreviewed]RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};+++[C9JY79_HUMAN|Unreviewed]RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};+++[M0QZQ3_HUMAN|Unreviewed]RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};+++[M0R1V6_HUMAN|Unreviewed]SubName: Full=Spectrin beta chain, non-erythrocytic 4 {ECO:0000313|Ensembl:ENSP00000472136}; Flags: Fragment;"]
[5775,"'PTPN4'",421,288,330,346.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0009898///cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0008092///cytoskeletal protein binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity","GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0071345///cellular response to cytokine stimulus","protein tyrosine phosphatase, non-receptor type 4","[PTN4_HUMAN|Reviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type 4; EC=3.1.3.48; AltName: Full=Protein-tyrosine phosphatase MEG1; Short=MEG; Short=PTPase-MEG1;+++[A0A024RAE8_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type {ECO:0000256|PIRNR:PIRNR000927}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR000927};+++[F5H020_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 4 {ECO:0000313|Ensembl:ENSP00000438445}; Flags: Fragment;+++[J3KQD3_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 4 {ECO:0000313|Ensembl:ENSP00000394706}; Flags: Fragment;+++[J3KQP5_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 4 {ECO:0000313|Ensembl:ENSP00000405763}; Flags: Fragment;+++[J3QT41_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 4 {ECO:0000313|Ensembl:ENSP00000387457}; Flags: Fragment;+++[J3QT59_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 4 {ECO:0000313|Ensembl:ENSP00000395603}; Flags: Fragment;+++[J3QT89_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 4 {ECO:0000313|Ensembl:ENSP00000411364}; Flags: Fragment;+++[Q4ZG31_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PTPN4 {ECO:0000313|EMBL:AAX88858.1}; Flags: Fragment;+++[Q53Q76_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PTPN4 {ECO:0000313|EMBL:AAY14805.1}; Flags: Fragment;+++[Q53QV5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PTPN4 {ECO:0000313|EMBL:AAY24016.1}; Flags: Fragment;+++[Q580X3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PTPN4 {ECO:0000313|EMBL:AAX82012.1}; Flags: Fragment;"]
[57801,"'HES4'",214,245,183,214,"05165///Human papillomavirus infection",{"$nulls":3},"GO:0005634///nucleus","GO:0003714///transcription corepressor activity+++GO:0043565///sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050767///regulation of neurogenesis+++GO:0001756///somitogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0007275///multicellular organism development","hes family bHLH transcription factor 4","[HES4_HUMAN|Reviewed]RecName: Full=Transcription factor HES-4; Short=hHES4; AltName: Full=Class B basic helix-loop-helix protein 42; Short=bHLHb42; AltName: Full=Hairy and enhancer of split 4; AltName: Full=bHLH factor Hes4;+++[D6REB3_HUMAN|Unreviewed]SubName: Full=Transcription factor HES-4 {ECO:0000313|Ensembl:ENSP00000425085};+++[E9PB28_HUMAN|Unreviewed]SubName: Full=Transcription factor HES-4 {ECO:0000313|Ensembl:ENSP00000393198};"]
[57834,"'CYP4F11'",7,5,6,6,{"$nulls":4},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0004497///monooxygenase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0005506///iron ion binding+++GO:0005504///fatty acid binding","GO:0042361///menaquinone catabolic process+++GO:0055114///oxidation-reduction process+++GO:0006954///inflammatory response+++GO:0042377///vitamin K catabolic process+++GO:0042376///phylloquinone catabolic process+++GO:0006631///fatty acid metabolic process+++GO:0007596///blood coagulation","cytochrome P450 family 4 subfamily F member 11","[CP4FB_HUMAN|Reviewed]RecName: Full=Phylloquinone omega-hydroxylase CYP4F11 {ECO:0000305}; EC=1.14.14.78 {ECO:0000269|PubMed:24138531}; AltName: Full=3-hydroxy fatty acids omega-hydroxylase CYP4F11 {ECO:0000305}; EC=1.14.14.- {ECO:0000305}; AltName: Full=Cytochrome P450 4F11; Short=CYPIVF11;+++[F8W978_HUMAN|Unreviewed]SubName: Full=Phylloquinone omega-hydroxylase CYP4F11 {ECO:0000313|Ensembl:ENSP00000319859};+++[V9GYP6_HUMAN|Unreviewed]SubName: Full=Phylloquinone omega-hydroxylase CYP4F11 {ECO:0000313|Ensembl:ENSP00000476972};"]
[580,"'BARD1'",29,17,29,25,"03440///Homologous recombination",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0070531///BRCA1-A complex+++GO:0031436///BRCA1-BARD1 complex+++GO:0000151///ubiquitin ligase complex+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0019900///kinase binding+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0003723///RNA binding","GO:0001894///tissue homeostasis+++GO:0007050///cell cycle arrest+++GO:0085020///protein K6-linked ubiquitination+++GO:0046826///negative regulation of protein export from nucleus+++GO:0006260///DNA replication+++GO:0016567///protein ubiquitination+++GO:0006281///DNA repair+++GO:0000729///DNA double-strand break processing+++GO:0043065///positive regulation of apoptotic process+++GO:0031441///negative regulation of mRNA 3'-end processing+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0042325///regulation of phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045732///positive regulation of protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0043066///negative regulation of apoptotic process","BRCA1 associated RING domain 1","[BARD1_HUMAN|Reviewed]RecName: Full=BRCA1-associated RING domain protein 1; Short=BARD-1; EC=2.3.2.27 {ECO:0000269|PubMed:12890688, ECO:0000269|PubMed:20351172}; AltName: Full=RING-type E3 ubiquitin transferase BARD1 {ECO:0000305};+++[A0A087WZ19_HUMAN|Unreviewed]SubName: Full=BRCA1-associated RING domain protein 1 {ECO:0000313|Ensembl:ENSP00000482293};+++[A0A087X0C6_HUMAN|Unreviewed]SubName: Full=BRCA1-associated RING domain protein 1 {ECO:0000313|Ensembl:ENSP00000483275};+++[A0A087X2H0_HUMAN|Unreviewed]SubName: Full=BRCA1-associated RING domain protein 1 {ECO:0000313|Ensembl:ENSP00000484976};+++[A0AVN2_HUMAN|Unreviewed]SubName: Full=BRCA1 associated RING domain 1 {ECO:0000313|EMBL:AAI26429.1};+++[C9IYG1_HUMAN|Unreviewed]SubName: Full=BRCA1-associated RING domain protein 1 {ECO:0000313|Ensembl:ENSP00000392245}; Flags: Fragment;+++[C9J6M1_HUMAN|Unreviewed]SubName: Full=BRCA1-associated RING domain protein 1 {ECO:0000313|Ensembl:ENSP00000405020}; Flags: Fragment;+++[F6MDI0_HUMAN|Unreviewed]SubName: Full=BRCA1 associated RING domain 1 isoform phi {ECO:0000313|EMBL:AEF57474.1};+++[F6MDI1_HUMAN|Unreviewed]SubName: Full=BRCA1 associated RING domain 1 isoform delta {ECO:0000313|EMBL:AEF57475.1}; SubName: Full=BRCA1-associated RING domain protein 1 {ECO:0000313|Ensembl:ENSP00000484464};+++[F6MDI2_HUMAN|Unreviewed]SubName: Full=BRCA1 associated RING domain 1 isoform epsilon {ECO:0000313|EMBL:AEF57476.1}; Flags: Fragment;+++[F6MDI3_HUMAN|Unreviewed]SubName: Full=BRCA1 associated RING domain 1 isoform eta {ECO:0000313|EMBL:AEF57477.1};+++[F6MDI4_HUMAN|Unreviewed]SubName: Full=BRCA1 associated RING domain 1 isoform pi {ECO:0000313|EMBL:AEF57478.1}; Flags: Fragment;+++[F8WCG2_HUMAN|Unreviewed]SubName: Full=BRCA1-associated RING domain protein 1 {ECO:0000313|Ensembl:ENSP00000412186};"]
[5816,"'PVALB'",0,2,1,1,{"$nulls":4},"GO:0005634///nucleus+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity+++GO:0005509///calcium ion binding","GO:0051480///regulation of cytosolic calcium ion concentration","parvalbumin","[PRVA_HUMAN|Reviewed]RecName: Full=Parvalbumin alpha;+++[A0A024R1K9_HUMAN|Unreviewed]SubName: Full=Parvalbumin, isoform CRA_a {ECO:0000313|EMBL:EAW60120.1};+++[B1AH72_HUMAN|Unreviewed]SubName: Full=Parvalbumin alpha {ECO:0000313|Ensembl:ENSP00000386089};+++[B8ZZ19_HUMAN|Unreviewed]SubName: Full=Parvalbumin alpha {ECO:0000313|Ensembl:ENSP00000406977}; Flags: Fragment;+++[H0Y3U0_HUMAN|Unreviewed]SubName: Full=Parvalbumin alpha {ECO:0000313|Ensembl:ENSP00000384735}; Flags: Fragment;"]
[5836,"'PYGL'",1284,1203,1355,1280.66666666667,"01100///Metabolic pathways+++00500///Starch and sucrose metabolism+++01110///Biosynthesis of secondary metabolites+++04931///Insulin resistance+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++02026///Biofilm formation - Escherichia coli+++04217///Necroptosis","H01760///Hepatic glycogen storage disease+++H01943///Glycogen storage disease type V+++H01762///Muscle glycogen storage disease+++H01944///Glycogen storage disease type VI+++H00069///Glycogen storage diseases (GSD)",null,"R02111///1,4-alpha-D-Glucan:orthophosphate alpha-D-glucosyltransferase   Starch + Orthophosphate <=> Amylose + D-Glucose 1-phosphate","GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0034774///secretory granule lumen+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005737///cytoplasm","GO:0030246///carbohydrate binding+++GO:0102250///linear malto-oligosaccharide phosphorylase activity+++GO:0019842///vitamin binding+++GO:0000166///nucleotide binding+++GO:0032052///bile acid binding+++GO:0005536///glucose binding+++GO:0002060///purine nucleobase binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008184///glycogen phosphorylase activity+++GO:0016208///AMP binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0042803///protein homodimerization activity+++GO:0030170///pyridoxal phosphate binding+++GO:0004645///phosphorylase activity+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0008144///drug binding+++GO:0102499///SHG alpha-glucan phosphorylase activity","GO:0070266///necroptotic process+++GO:0043312///neutrophil degranulation+++GO:0009617///response to bacterium+++GO:0005980///glycogen catabolic process+++GO:0008152///metabolic process+++GO:0005977///glycogen metabolic process+++GO:0006015///5-phosphoribose 1-diphosphate biosynthetic process+++GO:0042593///glucose homeostasis+++GO:0005975///carbohydrate metabolic process","glycogen phosphorylase L","[PYGL_HUMAN|Reviewed]RecName: Full=Glycogen phosphorylase, liver form; EC=2.4.1.1;+++[E9PK47_HUMAN|Unreviewed]RecName: Full=Alpha-1,4 glucan phosphorylase {ECO:0000256|RuleBase:RU000587}; EC=2.4.1.1 {ECO:0000256|RuleBase:RU000587};+++[Q6P1L4_HUMAN|Unreviewed]RecName: Full=Alpha-1,4 glucan phosphorylase {ECO:0000256|RuleBase:RU000587}; EC=2.4.1.1 {ECO:0000256|RuleBase:RU000587}; Flags: Fragment;"]
[58487,"'CREBZF'",302,248,246,265.333333333333,null,"H01020///Optic atrophy (OPA)",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0003700///DNA-binding transcription factor activity+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0045814///negative regulation of gene expression, epigenetic+++GO:0009615///response to virus+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","CREB/ATF bZIP transcription factor","[ZHANG_HUMAN|Reviewed]RecName: Full=CREB/ATF bZIP transcription factor; AltName: Full=Host cell factor-binding transcription factor Zhangfei; Short=HCF-binding transcription factor Zhangfei;+++[E9PIM0_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000435762};+++[E9PRP7_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000435980};+++[H0YDC7_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000433380}; Flags: Fragment;+++[J3KN20_HUMAN|Unreviewed]SubName: Full=CREB/ATF bZIP transcription factor {ECO:0000313|Ensembl:ENSP00000260058}; Flags: Fragment;"]
[58513,"'EPS15L1'",944.02,935.04,973,950.686666666667,"04144///Endocytosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005905///clathrin-coated pit+++GO:0005829///cytosol+++GO:0030132///clathrin coat of coated pit+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0045296///cadherin binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0061024///membrane organization+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0006897///endocytosis","epidermal growth factor receptor pathway substrate 15 like 1","[EP15R_HUMAN|Reviewed]RecName: Full=Epidermal growth factor receptor substrate 15-like 1; AltName: Full=Eps15-related protein; Short=Eps15R;+++[A0A024R7G6_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor pathway substrate 15-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW84543.1};+++[A5PKY0_HUMAN|Unreviewed]SubName: Full=EPS15L1 protein {ECO:0000313|EMBL:AAI42663.1}; Flags: Fragment;+++[K7EJR2_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000465286};+++[M0QX30_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000468866}; Flags: Fragment;+++[M0QY01_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000469495}; Flags: Fragment;+++[M0R165_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000471662};+++[M0R1V5_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000472135};+++[M0R2S2_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000472771};+++[M0R330_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000472958};+++[M0R3I1_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor receptor substrate 15-like 1 {ECO:0000313|Ensembl:ENSP00000473242}; Flags: Fragment;"]
[58538,"'MPP4'",1,2,2,1.66666666666667,"04530///Tight junction",{"$nulls":3},"GO:0005829///cytosol+++GO:0005913///cell-cell adherens junction+++GO:0015629///actin cytoskeleton+++GO:0032991///protein-containing complex",null,"GO:0035418///protein localization to synapse","membrane palmitoylated protein 4","[MPP4_HUMAN|Reviewed]RecName: Full=MAGUK p55 subfamily member 4; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein; AltName: Full=Discs large homolog 6;+++[A0A087WUS1_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000478875};+++[A2RU80_HUMAN|Unreviewed]SubName: Full=MPP4 protein {ECO:0000313|EMBL:AAI32786.1};+++[B7ZM19_HUMAN|Unreviewed]SubName: Full=MPP4 protein {ECO:0000313|EMBL:AAI44207.1};+++[E7ET46_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000416781};+++[E7EUL8_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000406160};+++[E9PG92_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000380095};+++[F6Q0Y6_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000387293};+++[F8WBH8_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000386580};+++[R4GN59_HUMAN|Unreviewed]SubName: Full=MAGUK p55 subfamily member 4 {ECO:0000313|Ensembl:ENSP00000473500}; Flags: Fragment;"]
[5879,"'RAC1'",4138,3972,3883,3997.66666666667,"04650///Natural killer cell mediated cytotoxicity+++04933///AGE-RAGE signaling pathway in diabetic complications+++05163///Human cytomegalovirus infection+++04024///cAMP signaling pathway+++04062///Chemokine signaling pathway+++05131///Shigellosis+++05211///Renal cell carcinoma+++04151///PI3K-Akt signaling pathway+++04010///MAPK signaling pathway+++05212///Pancreatic cancer+++04810///Regulation of actin cytoskeleton+++04722///Neurotrophin signaling pathway+++05231///Choline metabolism in cancer+++05203///Viral carcinogenesis+++04071///Sphingolipid signaling pathway+++04014///Ras signaling pathway+++04015///Rap1 signaling pathway+++04370///VEGF signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04380///Osteoclast differentiation+++05205///Proteoglycans in cancer+++04666///Fc gamma R-mediated phagocytosis+++04520///Adherens junction+++04310///Wnt signaling pathway+++04360///Axon guidance+++05418///Fluid shear stress and atherosclerosis+++05210///Colorectal cancer+++05132///Salmonella infection+++05014///Amyotrophic lateral sclerosis (ALS)+++04620///Toll-like receptor signaling pathway+++04013///MAPK signaling pathway - fly+++04664///Fc epsilon RI signaling pathway+++04145///Phagosome+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05100///Bacterial invasion of epithelial cells+++05416///Viral myocarditis+++05200///Pathways in cancer+++04662///B cell receptor signaling pathway+++04972///Pancreatic secretion+++04530///Tight junction+++04670///Leukocyte transendothelial migration+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04510///Focal adhesion","H00773///Autosomal dominant mental retardation",null,null,"GO:0005886///plasma membrane+++GO:0071944///cell periphery+++GO:0031941///filamentous actin+++GO:0043025///neuronal cell body+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0030027///lamellipodium+++GO:0042470///melanosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0030426///growth cone","GO:0051022///Rho GDP-dissociation inhibitor binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0048306///calcium-dependent protein binding","GO:0014041///regulation of neuron maturation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0001764///neuron migration+++GO:0021894///cerebral cortex GABAergic interneuron development+++GO:0001934///positive regulation of protein phosphorylation+++GO:0030031///cell projection assembly+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0007264///small GTPase mediated signal transduction+++GO:0035556///intracellular signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0051932///synaptic transmission, GABAergic+++GO:0030334///regulation of cell migration+++GO:0050885///neuromuscular process controlling balance+++GO:0048870///cell motility+++GO:0031175///neuron projection development+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0051056///regulation of small GTPase mediated signal transduction","Rac family small GTPase 1","[RAC1_HUMAN|Reviewed]RecName: Full=Ras-related C3 botulinum toxin substrate 1; AltName: Full=Cell migration-inducing gene 5 protein; AltName: Full=Ras-like protein TC25; AltName: Full=p21-Rac1; Flags: Precursor;+++[A4D2P0_HUMAN|Unreviewed]SubName: Full=Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1) {ECO:0000313|EMBL:EAL23718.1}; SubName: Full=Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_e {ECO:0000313|EMBL:EAW55044.1}; SubName: Full=cDNA FLJ77333, highly similar to Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1b, mRNA {ECO:0000313|EMBL:BAF84504.1};+++[A4D2P1_HUMAN|Unreviewed]SubName: Full=Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1) {ECO:0000313|EMBL:EAL23719.1}; SubName: Full=Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1), isoform CRA_a {ECO:0000313|EMBL:EAW55039.1}; SubName: Full=Ras-related C3 botulinum toxin substrate 1 isoform Rac1 {ECO:0000313|EMBL:BAG70052.1}; SubName: Full=cDNA FLJ30431 fis, clone BRACE2008968, highly similar to Ras-related C3 botulinum toxin substrate 1 {ECO:0000313|EMBL:BAG51447.1}; SubName: Full=cDNA FLJ75553, highly similar to Homo sapiens ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) (RAC1), transcript variant Rac1, mRNA {ECO:0000313|EMBL:BAF84495.1};"]
[5888,"'RAD51'",5,9,7,7,"03460///Fanconi anemia pathway+++05212///Pancreatic cancer+++05200///Pathways in cancer+++03440///Homologous recombination","H01287///Congenital mirror movements (CMM)+++H00238///Fanconi anemia",null,null,"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000228///nuclear chromosome+++GO:0000785///chromatin+++GO:0035861///site of double-strand break+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0000800///lateral element+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0000793///condensed chromosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005730///nucleolus+++GO:0016605///PML body+++GO:0000794///condensed nuclear chromosome+++GO:0032991///protein-containing complex","GO:0019899///enzyme binding+++GO:0070182///DNA polymerase binding+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0043142///single-stranded DNA-dependent ATPase activity+++GO:0005524///ATP binding+++GO:0003697///single-stranded DNA binding+++GO:0000150///recombinase activity+++GO:0003682///chromatin binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0003690///double-stranded DNA binding","GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0007131///reciprocal meiotic recombination+++GO:0010833///telomere maintenance via telomere lengthening+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000722///telomere maintenance via recombination+++GO:0000724///double-strand break repair via homologous recombination+++GO:0072757///cellular response to camptothecin+++GO:0000730///DNA recombinase assembly+++GO:0042148///strand invasion+++GO:0051260///protein homooligomerization+++GO:0006312///mitotic recombination+++GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:0006259///DNA metabolic process+++GO:0006268///DNA unwinding involved in DNA replication+++GO:1990426///mitotic recombination-dependent replication fork processing+++GO:0051106///positive regulation of DNA ligation+++GO:0051321///meiotic cell cycle+++GO:0071479///cellular response to ionizing radiation+++GO:0031297///replication fork processing+++GO:0036297///interstrand cross-link repair","RAD51 recombinase","[RAD51_HUMAN|Reviewed]RecName: Full=DNA repair protein RAD51 homolog 1; Short=HsRAD51; Short=hRAD51; AltName: Full=RAD51 homolog A;+++[E9PI54_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD51 homolog 1 {ECO:0000313|Ensembl:ENSP00000436512};+++[E9PJ30_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD51 homolog 1 {ECO:0000313|Ensembl:ENSP00000431864};+++[E9PNT5_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD51 homolog 1 {ECO:0000313|Ensembl:ENSP00000432759}; Flags: Fragment;+++[H0YD61_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD51 homolog 1 {ECO:0000313|Ensembl:ENSP00000433053}; Flags: Fragment;+++[Q9NZG9_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD51 homolog 1 {ECO:0000313|Ensembl:ENSP00000431897}; Flags: Fragment;"]
[5911,"'RAP2A'",512,357,480,449.666666666667,{"$nulls":4},"GO:0055037///recycling endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0055038///recycling endosome membrane+++GO:0030496///midbody+++GO:0005829///cytosol+++GO:0005768///endosome","GO:0003924///GTPase activity+++GO:0000287///magnesium ion binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0005515///protein binding","GO:0031954///positive regulation of protein autophosphorylation+++GO:0031532///actin cytoskeleton reorganization+++GO:0030033///microvillus assembly+++GO:0001934///positive regulation of protein phosphorylation+++GO:0032486///Rap protein signal transduction+++GO:0045184///establishment of protein localization+++GO:0034613///cellular protein localization+++GO:0072659///protein localization to plasma membrane+++GO:0035690///cellular response to drug+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0030336///negative regulation of cell migration+++GO:0046328///regulation of JNK cascade+++GO:0048814///regulation of dendrite morphogenesis+++GO:0007165///signal transduction","RAP2A, member of RAS oncogene family","[RAP2A_HUMAN|Reviewed]RecName: Full=Ras-related protein Rap-2a; AltName: Full=RbBP-30; Flags: Precursor;+++[F6U784_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rap-2a {ECO:0000313|Ensembl:ENSP00000436462};"]
[5918,"'RARRES1'",48,51,50,49.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00891///Combined oxidative phosphorylation deficiency (COXPD)+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0003677///DNA binding+++GO:0005525///GTP binding+++GO:0003746///translation elongation factor activity+++GO:0046872///metal ion binding+++GO:0003924///GTPase activity+++GO:0003723///RNA binding","GO:0008285///negative regulation of cell proliferation","retinoic acid receptor responder 1","[TIG1_HUMAN|Reviewed]RecName: Full=Retinoic acid receptor responder protein 1; AltName: Full=Phorbol ester-induced gene 1 protein; Short=PERG-1; AltName: Full=RAR-responsive protein TIG1; AltName: Full=Tazarotene-induced gene 1 protein;"]
[5933,"'RBL1'",55.58,32,39.16,42.2466666666667,"04110///Cell cycle+++05203///Viral carcinogenesis+++05165///Human papillomavirus infection+++04218///Cellular senescence+++04350///TGF-beta signaling pathway",null,"M00692///Cell cycle - G1/S transition",null,"GO:0005576///extracellular region+++GO:0000785///chromatin+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:1990841///promoter-specific chromatin binding+++GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0001012///RNA polymerase II regulatory region DNA binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0008134///transcription factor binding","GO:0007346///regulation of mitotic cell cycle+++GO:0043550///regulation of lipid kinase activity+++GO:0051726///regulation of cell cycle+++GO:0007049///cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000773///negative regulation of cellular senescence+++GO:0051302///regulation of cell division+++GO:0008150///biological_process+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0016032///viral process+++GO:0006325///chromatin organization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010629///negative regulation of gene expression","RB transcriptional corepressor like 1","[RBL1_HUMAN|Reviewed]RecName: Full=Retinoblastoma-like protein 1; AltName: Full=107 kDa retinoblastoma-associated protein; Short=p107; AltName: Full=pRb1;+++[A0A0D9SET1_HUMAN|Unreviewed]SubName: Full=Basic salivary proline-rich protein 1 {ECO:0000313|Ensembl:ENSP00000485971}; SubName: Full=HCG26567, isoform CRA_a {ECO:0000313|EMBL:EAW96232.1};+++[A0A0G2JM13_HUMAN|Unreviewed]SubName: Full=Basic salivary proline-rich protein 1 {ECO:0000313|Ensembl:ENSP00000478365};+++[A0A0G2JMN8_HUMAN|Unreviewed]SubName: Full=Basic salivary proline-rich protein 1 {ECO:0000313|Ensembl:ENSP00000479646};+++[A0A0G2JQ42_HUMAN|Unreviewed]SubName: Full=Basic salivary proline-rich protein 1 {ECO:0000313|Ensembl:ENSP00000484902};+++[A0A0G2JR74_HUMAN|Unreviewed]SubName: Full=Basic salivary proline-rich protein 1 {ECO:0000313|Ensembl:ENSP00000486506};+++[A0A0G2JRP6_HUMAN|Unreviewed]SubName: Full=Basic salivary proline-rich protein 1 {ECO:0000313|Ensembl:ENSP00000486960};+++[A5D903_HUMAN|Unreviewed]SubName: Full=PRB1 protein {ECO:0000313|EMBL:AAI41918.1};+++[E9PNB6_HUMAN|Unreviewed]SubName: Full=Retinoblastoma-like protein 1 {ECO:0000313|Ensembl:ENSP00000437240};+++[G3V1M9_HUMAN|Unreviewed]SubName: Full=Basic salivary proline-rich protein 1 {ECO:0000313|Ensembl:ENSP00000442127};+++[H0YE05_HUMAN|Unreviewed]SubName: Full=Retinoblastoma-like protein 1 {ECO:0000313|Ensembl:ENSP00000434711}; Flags: Fragment;+++[Q86YA1_HUMAN|Unreviewed]SubName: Full=PRB1 protein {ECO:0000313|EMBL:AAH44827.1}; Flags: Fragment;+++[Q8WVU8_HUMAN|Unreviewed]SubName: Full=RBL1 protein {ECO:0000313|EMBL:AAH17557.1}; Flags: Fragment;"]
[59340,"'HRH4'",1,0,1,0.666666666666667,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0030425///dendrite+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005623///cell","GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0004969///histamine receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007268///chemical synaptic transmission+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007165///signal transduction+++GO:0008150///biological_process+++GO:0043408///regulation of MAPK cascade+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:0006954///inflammatory response","histamine receptor H4","[HRH4_HUMAN|Reviewed]RecName: Full=Histamine H4 receptor; Short=H4R; Short=HH4R; AltName: Full=AXOR35; AltName: Full=G-protein coupled receptor 105; AltName: Full=GPRv53; AltName: Full=Pfi-013; AltName: Full=SP9144;+++[B2KJ49_HUMAN|Unreviewed]SubName: Full=Histamine H4 receptor isoform 67 {ECO:0000313|EMBL:ABI54175.1};+++[Q96LD9_HUMAN|Unreviewed]SubName: Full=Histamine receptor H4 {ECO:0000313|EMBL:AAL09297.1};"]
[59353,"'TMEM35A'",12,9,18,13,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005778///peroxisomal membrane+++GO:0005575///cellular_component+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane+++GO:0005777///peroxisome+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0008150///biological_process","transmembrane protein 35A","[TM35A_HUMAN|Reviewed]RecName: Full=Transmembrane protein 35A;"]
[5971,"'RELB'",79,144,83,102,"04380///Osteoclast differentiation+++04010///MAPK signaling pathway+++05169///Epstein-Barr virus infection+++04625///C-type lectin receptor signaling pathway+++05166///HTLV-I infection+++04064///NF-kappa B signaling pathway",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005815///microtubule organizing center+++GO:0017053///transcriptional repressor complex+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding+++GO:0003682///chromatin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0042088///T-helper 1 type immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045063///T-helper 1 cell differentiation+++GO:0010628///positive regulation of gene expression+++GO:0034097///response to cytokine+++GO:0032688///negative regulation of interferon-beta production+++GO:0006954///inflammatory response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032922///circadian regulation of gene expression+++GO:0048511///rhythmic process+++GO:0043011///myeloid dendritic cell differentiation+++GO:0071470///cellular response to osmotic stress+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0038061///NIK/NF-kappaB signaling+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0019882///antigen processing and presentation+++GO:0030098///lymphocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","RELB proto-oncogene, NF-kB subunit","[RELB_HUMAN|Reviewed]RecName: Full=Transcription factor RelB; AltName: Full=I-Rel;+++[D6R992_HUMAN|Unreviewed]SubName: Full=Transcription factor RelB {ECO:0000313|Ensembl:ENSP00000423287}; SubName: Full=V-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (Avian) {ECO:0000313|EMBL:EAW57316.1};+++[D6RIV7_HUMAN|Unreviewed]SubName: Full=Transcription factor RelB {ECO:0000313|Ensembl:ENSP00000427348};+++[K7ERX9_HUMAN|Unreviewed]SubName: Full=Transcription factor RelB {ECO:0000313|Ensembl:ENSP00000468460}; Flags: Fragment;"]
[5985,"'RFC5'",96,67,60,74.3333333333333,"03030///DNA replication+++03430///Mismatch repair+++03420///Nucleotide excision repair",null,"M00289///RF-C complex+++M00295///BRCA1-associated genome surveillance complex (BASC)",null,"GO:0005663///DNA replication factor C complex+++GO:0031390///Ctf18 RFC-like complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003689///DNA clamp loader activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0043142///single-stranded DNA-dependent ATPase activity+++GO:0003677///DNA binding+++GO:0000166///nucleotide binding+++GO:0019899///enzyme binding","GO:0006261///DNA-dependent DNA replication+++GO:0006260///DNA replication+++GO:1900264///positive regulation of DNA-directed DNA polymerase activity+++GO:0006281///DNA repair+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0042276///error-prone translesion synthesis+++GO:0032201///telomere maintenance via semi-conservative replication+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0019985///translesion synthesis+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0070987///error-free translesion synthesis+++GO:0033683///nucleotide-excision repair, DNA incision","replication factor C subunit 5","[RFC5_HUMAN|Reviewed]RecName: Full=Replication factor C subunit 5; AltName: Full=Activator 1 36 kDa subunit; Short=A1 36 kDa subunit; AltName: Full=Activator 1 subunit 5; AltName: Full=Replication factor C 36 kDa subunit; Short=RF-C 36 kDa subunit; Short=RFC36;+++[C9JH72_HUMAN|Unreviewed]SubName: Full=Replication factor C subunit 5 {ECO:0000313|Ensembl:ENSP00000390340}; Flags: Fragment;+++[E9PEP3_HUMAN|Unreviewed]SubName: Full=Replication factor C subunit 5 {ECO:0000313|Ensembl:ENSP00000393636}; Flags: Fragment;+++[F5H0U6_HUMAN|Unreviewed]SubName: Full=Replication factor C subunit 5 {ECO:0000313|Ensembl:ENSP00000445917}; Flags: Fragment;+++[F5H304_HUMAN|Unreviewed]SubName: Full=Replication factor C subunit 5 {ECO:0000313|Ensembl:ENSP00000438252}; Flags: Fragment;+++[F5H5S0_HUMAN|Unreviewed]SubName: Full=Replication factor C subunit 5 {ECO:0000313|Ensembl:ENSP00000443187}; Flags: Fragment;+++[Q59GW7_HUMAN|Unreviewed]SubName: Full=Replication factor C 5 isoform 1 variant {ECO:0000313|EMBL:BAD92229.1}; Flags: Fragment;+++[Q6LES9_HUMAN|Unreviewed]SubName: Full=RFC5 protein {ECO:0000313|EMBL:CAG28579.1}; Flags: Fragment;"]
[6007,"'RHD'",1,1,0,0.666666666666667,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008519///ammonium transmembrane transporter activity+++GO:0003674///molecular_function","GO:0072488///ammonium transmembrane transport+++GO:0008150///biological_process+++GO:0015696///ammonium transport","Rh blood group D antigen",{"$cut":{"chars":32759,"head":"[RHD_HUMAN|Reviewed]RecName: Full=Blood group Rh(D) polypeptide; AltName: Full=RHXIII; AltName: Full=Rh polypeptide 2; Short=RhPII; AltName: Full=Rhesus D antigen; AltName: CD_antigen=CD240D;+++[A0A023W4F4_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AHY24798.1}; Flags: Fragment;+++[A0A023W596_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AHY24797.1}; Flags: Fragment;+++[A0A059XI04_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AIA22206.1}; Flags: Fragment;+++[A0A059XMR3_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AIA22207.1}; Flags: Fragment;+++[A0A068J745_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AIE13829.1};+++[A0A078BRP7_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CDX09878.1};+++[A0A078N210_HUMAN|Unreviewed]SubName: Full=Rhesus blood group, D antigen {ECO:0000313|EMBL:CED80063.1};+++[A0A096ZG20_HUMAN|Unreviewed]SubName: Full=Rhesus D {ECO:0000313|EMBL:AIR07396.1}; Flags: Fragment;+++[A0A098E5P3_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CEG06588.1};+++[A0A0A1CEV8_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AIX94461.1}; Flags: Fragment;+++[A0A0A1CJK9_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AIX94462.1}; Flags: Fragment;+++[A0A0A1TE45_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CEJ95646.1};+++[A0A0A1TJK6_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CEJ95644.1};+++[A0A0A1TSG7_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CEJ95645.1}; Flags: Fragment;+++[A0A0A1TST1_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CEJ95643.1}; Flags: Fragment;+++[A0A0A1TTP9_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CEJ95647.1}; Flags: Fragment;+++[A0A0A8WEA9_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CEK40166.1};+++[A0A0A8WGH0_HUMAN|Unreviewed]SubName: Full=Blood group antigen D {ECO:0000313|EMBL:CEK43029.1}; SubName: Full=Blood group protein RHD {ECO:0000313|EMBL:AMO00689.1};+++[A0A0A8WIW4_HUMAN|Unreviewed]SubName: Full=Rh blood group antigen D {ECO:0000313|EMBL:CEK43032.1};+++[A0A0D6EFI1_HUMAN|Unreviewed]SubName: Full=Rh blood group, D antigen {ECO:0000313|EMBL:CEP69644.1};+++[A0A0E4AYH7_HUMAN|Unreviewed]SubName: Full=RhD polypeptide {ECO:0000313|EMBL:BAR40328.1};+++[A0A0E4FHS6_HUMAN|Unreviewed]SubName: Full=RhD polypeptide {ECO:0000313|EMBL:BAR40329.1};+++[A0A0K0QNW0_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AKR14238.1}; Flags: Fragment;+++[A0A0K0QP18_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AKR14240.1}; Flags: Fragment;+++[A0A0K0QP22_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AKR14237.1}; Flags: Fragment;+++[A0A0K0QP25_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AKR14242.1}; Flags: Fragment;+++[A0A0K0QPX0_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AKR14241.1}; Flags: Fragment;+++[A0A0P1IVP9_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CUQ99284.2};+++[A0A0P1IVQ0_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CUQ99283.2};+++[A0A0P1IVV5_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CUQ99282.2};+++[A0A0S1Z226_HUMAN|Unreviewed]SubName: Full=RhD {ECO:0000313|EMBL:ALM96707.1};+++[A0A0U5KVZ8_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:CUX99967.1};+++[A0A120HTJ0_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AMA97174.1}; Flags: Fragment;+++[A0A140FA43_HUMAN|Unreviewed]SubName: Full=Rhesus blood group D antigen {ECO:0000313|EMBL:AML80885.1}; Flags: Fragment;+++[A0A140FA44_HUMAN|Unreviewed]SubName: Full=Rhesus blood gr"}}]
[60314,"'C12orf10'",480,602,550,544,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0035641///locomotory exploration behavior","chromosome 12 open reading frame 10","[MYG1_HUMAN|Reviewed]RecName: Full=UPF0160 protein MYG1, mitochondrial; Flags: Precursor;+++[F8VQQ3_HUMAN|Unreviewed]SubName: Full=UPF0160 protein MYG1, mitochondrial {ECO:0000313|Ensembl:ENSP00000450270};+++[F8VR84_HUMAN|Unreviewed]SubName: Full=UPF0160 protein MYG1, mitochondrial {ECO:0000313|Ensembl:ENSP00000448433};+++[H3BPH3_HUMAN|Unreviewed]SubName: Full=UPF0160 protein MYG1, mitochondrial {ECO:0000313|Ensembl:ENSP00000455319}; Flags: Fragment;+++[Q86UA3_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 10 {ECO:0000313|EMBL:AAH51871.1}; SubName: Full=Chromosome 12 open reading frame 10, isoform CRA_b {ECO:0000313|EMBL:EAW96688.1};+++[Q8WYI2_HUMAN|Unreviewed]SubName: Full=C12orf10 protein {ECO:0000313|EMBL:AAH28904.1}; SubName: Full=MSTP024 {ECO:0000313|EMBL:AAL39007.1};+++[Q96CT6_HUMAN|Unreviewed]SubName: Full=C12orf10 protein {ECO:0000313|EMBL:AAH13956.2}; Flags: Fragment;"]
[60484,"'HAPLN2'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region","GO:0005540///hyaluronic acid binding","GO:0008065///establishment of blood-nerve barrier+++GO:0007417///central nervous system development+++GO:0085029///extracellular matrix assembly+++GO:0007155///cell adhesion","hyaluronan and proteoglycan link protein 2","[HPLN2_HUMAN|Reviewed]RecName: Full=Hyaluronan and proteoglycan link protein 2; AltName: Full=Brain link protein 1; Flags: Precursor;+++[Q5T3J1_HUMAN|Unreviewed]SubName: Full=Hyaluronan and proteoglycan link protein 2 {ECO:0000313|Ensembl:ENSP00000388835}; Flags: Fragment;"]
[60509,"'AGBL5'",1372,1422,1342,1378.66666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0005819///spindle+++GO:0072686///mitotic spindle+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge","GO:0015631///tubulin binding+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008233///peptidase activity+++GO:0046872///metal ion binding+++GO:0004181///metallocarboxypeptidase activity","GO:0035608///protein deglutamylation+++GO:0051607///defense response to virus+++GO:0035611///protein branching point deglutamylation+++GO:0006508///proteolysis","ATP/GTP binding protein like 5","[CBPC5_HUMAN|Reviewed]RecName: Full=Cytosolic carboxypeptidase-like protein 5; EC=3.4.17.-; AltName: Full=ATP/GTP-binding protein-like 5;+++[C9JCE1_HUMAN|Unreviewed]SubName: Full=Cytosolic carboxypeptidase-like protein 5 {ECO:0000313|Ensembl:ENSP00000395266}; Flags: Fragment;+++[C9JHM6_HUMAN|Unreviewed]SubName: Full=Cytosolic carboxypeptidase-like protein 5 {ECO:0000313|Ensembl:ENSP00000395721}; Flags: Fragment;+++[C9JQG9_HUMAN|Unreviewed]SubName: Full=Cytosolic carboxypeptidase-like protein 5 {ECO:0000313|Ensembl:ENSP00000394730}; Flags: Fragment;+++[C9JTY1_HUMAN|Unreviewed]SubName: Full=Cytosolic carboxypeptidase-like protein 5 {ECO:0000313|Ensembl:ENSP00000407584}; Flags: Fragment;+++[H7C1L5_HUMAN|Unreviewed]SubName: Full=Cytosolic carboxypeptidase-like protein 5 {ECO:0000313|Ensembl:ENSP00000400905}; Flags: Fragment;"]
[60676,"'PAPPA2'",61,54,24,46.3333333333333,{"$nulls":4},"GO:0005622///intracellular+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0008270///zinc ion binding+++GO:0004222///metalloendopeptidase activity","GO:0044267///cellular protein metabolic process+++GO:0006508///proteolysis+++GO:0060349///bone morphogenesis+++GO:0009651///response to salt stress+++GO:0001558///regulation of cell growth","pappalysin 2","[PAPP2_HUMAN|Reviewed]RecName: Full=Pappalysin-2; EC=3.4.24.-; AltName: Full=Pregnancy-associated plasma protein A2; Short=PAPP-A2; AltName: Full=Pregnancy-associated plasma protein E1; Short=PAPP-E; Flags: Precursor;"]
[6096,"'RORB'",29,23,58,36.6666666666667,"04710///Circadian rhythm",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0004879///nuclear receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008502///melatonin receptor activity+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003707///steroid hormone receptor activity","GO:0048511///rhythmic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060041///retina development in camera-type eye+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0035881///amacrine cell differentiation+++GO:0071300///cellular response to retinoic acid+++GO:0046549///retinal cone cell development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0050896///response to stimulus+++GO:0007601///visual perception+++GO:0030522///intracellular receptor signaling pathway+++GO:0046548///retinal rod cell development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0042462///eye photoreceptor cell development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0042752///regulation of circadian rhythm","RAR related orphan receptor B","[RORB_HUMAN|Reviewed]RecName: Full=Nuclear receptor ROR-beta; AltName: Full=Nuclear receptor RZR-beta; AltName: Full=Nuclear receptor subfamily 1 group F member 2; AltName: Full=Retinoid-related orphan receptor-beta;+++[A0A1L4FMK7_HUMAN|Unreviewed]SubName: Full=RAR related orphan receptor B isoform 2 {ECO:0000313|EMBL:APJ36118.1};+++[B6ZGS5_HUMAN|Unreviewed]SubName: Full=Retinoid-related orphan receptor beta {ECO:0000313|EMBL:BAH02286.1};+++[Q58EY0_HUMAN|Unreviewed]SubName: Full=RAR related orphan receptor B isoform 1 {ECO:0000313|EMBL:APJ36117.1}; SubName: Full=RAR-related orphan receptor B {ECO:0000313|EMBL:AAH51830.1}; SubName: Full=RAR-related orphan receptor beta {ECO:0000313|EMBL:ADZ17393.1}; SubName: Full=cDNA, FLJ93970, Homo sapiens RAR-related orphan receptor B (RORB), mRNA {ECO:0000313|EMBL:BAG36222.1};"]
[6125,"'RPL5'",6765,6577,6656,6666,"03010///Ribosome","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0005737///cytoplasm+++GO:0005840///ribosome+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:1990904///ribonucleoprotein complex+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0005925///focal adhesion+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm","GO:0008097///5S rRNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003735///structural constituent of ribosome+++GO:0031625///ubiquitin protein ligase binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0019843///rRNA binding+++GO:1990948///ubiquitin ligase inhibitor activity","GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0042273///ribosomal large subunit biogenesis+++GO:0006364///rRNA processing+++GO:0006413///translational initiation+++GO:2000435///negative regulation of protein neddylation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0000027///ribosomal large subunit assembly+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0050821///protein stabilization+++GO:0010628///positive regulation of gene expression+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0045727///positive regulation of translation+++GO:0006412///translation","ribosomal protein L5","[RL5_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L5; AltName: Full=Large ribosomal subunit protein uL18 {ECO:0000303|PubMed:24524803};+++[A0A2R8Y4A2_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L5 {ECO:0000313|Ensembl:ENSP00000493811};+++[A0A2R8Y6J3_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L5 {ECO:0000313|Ensembl:ENSP00000495589}; Flags: Fragment;+++[A2RUM7_HUMAN|Unreviewed]SubName: Full=Ribosomal protein L5 {ECO:0000313|EMBL:AAI32971.1}; SubName: Full=Ribosomal protein L5, isoform CRA_c {ECO:0000313|EMBL:EAW73089.1}; SubName: Full=cDNA, FLJ95579, Homo sapiens ribosomal protein L5 (RPL5), mRNA {ECO:0000313|EMBL:BAG37264.1};+++[B3KTM6_HUMAN|Unreviewed]SubName: Full=Ribosomal protein L5, isoform CRA_b {ECO:0000313|EMBL:EAW73088.1}; SubName: Full=cDNA FLJ38496 fis, clone FELIV1000137, highly similar to 60S RIBOSOMAL PROTEIN L5 {ECO:0000313|EMBL:BAG53138.1};+++[Q5T7N0_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L5 {ECO:0000313|Ensembl:ENSP00000359338}; Flags: Fragment;+++[Q8WYP1_HUMAN|Unreviewed]SubName: Full=Ribosomal protein L5 {ECO:0000313|EMBL:BAB79486.1}; Flags: Fragment;+++[Q9BUV4_HUMAN|Unreviewed]SubName: Full=RPL5 protein {ECO:0000313|EMBL:AAH01882.1}; SubName: Full=Ribosomal protein L5, isoform CRA_a {ECO:0000313|EMBL:EAW73087.1};+++[R4GNJ2_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L5 {ECO:0000313|Ensembl:ENSP00000473675};"]
[6142,"'RPL18A'",13806,15384,14723,14637.6666666667,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0005840///ribosome+++GO:0045202///synapse+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0042788///polysomal ribosome","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003735///structural constituent of ribosome","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0002181///cytoplasmic translation+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0097327///response to antineoplastic agent","ribosomal protein L18a","[RL18A_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L18a; AltName: Full=Large ribosomal subunit protein eL20 {ECO:0000303|PubMed:24524803};+++[M0R0P7_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L18a {ECO:0000313|Ensembl:ENSP00000471360};+++[M0R117_HUMAN|Unreviewed]RecName: Full=60S ribosomal protein L18a {ECO:0000256|PIRNR:PIRNR002190};+++[M0R1A7_HUMAN|Unreviewed]RecName: Full=60S ribosomal protein L18a {ECO:0000256|PIRNR:PIRNR002190};+++[M0R3D6_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L18a {ECO:0000313|Ensembl:ENSP00000473155}; Flags: Fragment;"]
[6167,"'RPL37'",7138,7481,6162,6927,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes+++M00179///Ribosome, archaea",null,"GO:0022625///cytosolic large ribosomal subunit+++GO:0005840///ribosome+++GO:0005829///cytosol+++GO:0045202///synapse","GO:0019843///rRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0046872///metal ion binding+++GO:0003723///RNA binding","GO:0006412///translation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006413///translational initiation","ribosomal protein L37","[RL37_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L37; AltName: Full=G1.16; AltName: Full=Large ribosomal subunit protein eL37 {ECO:0000303|PubMed:24524803};+++[A0A024R0A2_HUMAN|Unreviewed]RecName: Full=Ribosomal protein L37 {ECO:0000256|RuleBase:RU000576};+++[D6R9X9_HUMAN|Unreviewed]RecName: Full=Ribosomal protein L37 {ECO:0000256|RuleBase:RU000576};+++[D6RG19_HUMAN|Unreviewed]RecName: Full=Ribosomal protein L37 {ECO:0000256|RuleBase:RU000576};"]
[6187,"'RPS2'",31308,35179,33674,33387,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005730///nucleolus+++GO:1990904///ribonucleoprotein complex+++GO:0022627///cytosolic small ribosomal subunit+++GO:0070062///extracellular exosome+++GO:0015935///small ribosomal subunit+++GO:0005654///nucleoplasm+++GO:0005840///ribosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0017134///fibroblast growth factor binding+++GO:0019899///enzyme binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0045296///cadherin binding","GO:0006364///rRNA processing+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0006412///translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006413///translational initiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","ribosomal protein S2","[RS2_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S2; AltName: Full=40S ribosomal protein S4; AltName: Full=Protein LLRep3; AltName: Full=Small ribosomal subunit protein uS5 {ECO:0000303|PubMed:24524803};+++[D3DU83_HUMAN|Unreviewed]SubName: Full=Ribosomal protein S2, isoform CRA_c {ECO:0000313|EMBL:EAW85596.1};+++[E9PM36_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000433170};+++[E9PMM9_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000433034}; Flags: Fragment;+++[E9PPT0_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000436356};+++[E9PQD7_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000436865};+++[H0YE27_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000434846}; Flags: Fragment;+++[H0YEN5_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000436227}; Flags: Fragment;+++[H3BNG3_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000454837}; Flags: Fragment;+++[I3L404_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S2 {ECO:0000313|Ensembl:ENSP00000460860}; Flags: Fragment;+++[Q3KQT6_HUMAN|Unreviewed]SubName: Full=Ribosomal protein S2 {ECO:0000313|EMBL:AAI06061.1};+++[Q6IPX5_HUMAN|Unreviewed]SubName: Full=Ribosomal protein S2 {ECO:0000313|EMBL:AAH71673.1};+++[Q8N5L9_HUMAN|Unreviewed]SubName: Full=Ribosomal protein S2 {ECO:0000313|EMBL:AAH32129.1};+++[Q9BSW5_HUMAN|Unreviewed]SubName: Full=RPS2 protein {ECO:0000313|EMBL:AAH04520.2}; Flags: Fragment;"]
[6204,"'RPS10'",5577,5917,5396,5630,"03010///Ribosome","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005829///cytosol+++GO:0005840///ribosome+++GO:0005730///nucleolus+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000028///ribosomal small subunit assembly+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006413///translational initiation+++GO:0006412///translation","ribosomal protein S10","[RS10_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S10; AltName: Full=Small ribosomal subunit protein eS10 {ECO:0000303|PubMed:24524803};+++[A0A2R8Y7H1_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S10 {ECO:0000313|Ensembl:ENSP00000496022};+++[A0A2R8YFH6_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S10 {ECO:0000313|Ensembl:ENSP00000495142};+++[F6U211_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S10 {ECO:0000313|Ensembl:ENSP00000363169};"]
[6227,"'RPS21'",960,1030,886,958.666666666667,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0005791///rough endoplasmic reticulum+++GO:0005783///endoplasmic reticulum+++GO:0042788///polysomal ribosome+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0005840///ribosome+++GO:0005737///cytoplasm+++GO:0015935///small ribosomal subunit+++GO:0005654///nucleoplasm+++GO:0022627///cytosolic small ribosomal subunit","GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006413///translational initiation+++GO:0000461///endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0002181///cytoplasmic translation+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006412///translation","ribosomal protein S21","[RS21_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S21; AltName: Full=Small ribosomal subunit protein eS21 {ECO:0000303|PubMed:24524803};+++[Q6FGH5_HUMAN|Unreviewed]SubName: Full=RPS21 protein {ECO:0000313|EMBL:CAG46929.1}; SubName: Full=Ribosomal protein S21 {ECO:0000313|EMBL:AAH21990.1}; SubName: Full=Ribosomal protein S21, isoform CRA_d {ECO:0000313|EMBL:EAW75370.1}; Flags: Fragment;+++[Q8WVC2_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein S21 {ECO:0000256|PIRNR:PIRNR002148};+++[Q9BYK1_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S21 {ECO:0000313|Ensembl:ENSP00000359624}; SubName: Full=Ribosomal protein S21, isoform CRA_e {ECO:0000313|EMBL:EAW75371.1};+++[Q9BYK2_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S21 {ECO:0000313|Ensembl:ENSP00000359593}; SubName: Full=Ribosomal protein S21, isoform CRA_c {ECO:0000313|EMBL:EAW75369.1};"]
[6230,"'RPS25'",5790,6855,5748,6131,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0005840///ribosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0070062///extracellular exosome+++GO:0015935///small ribosomal subunit+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005730///nucleolus","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0006412///translation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006413///translational initiation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane","ribosomal protein S25","[RS25_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S25; AltName: Full=Small ribosomal subunit protein eS25 {ECO:0000303|PubMed:24524803};+++[E9PK60_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S25 {ECO:0000313|Ensembl:ENSP00000431634};+++[E9PQK3_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S25 {ECO:0000313|Ensembl:ENSP00000436193};"]
[6271,"'S100A1'",171,199,215,195,{"$nulls":4},"GO:0031430///M band+++GO:0031674///I band+++GO:0031672///A band+++GO:0016529///sarcoplasmic reticulum+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0030018///Z disc+++GO:0032991///protein-containing complex","GO:0044548///S100 protein binding+++GO:0042802///identical protein binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0048306///calcium-dependent protein binding+++GO:0051117///ATPase binding+++GO:0042803///protein homodimerization activity","GO:0021762///substantia nigra development+++GO:0008016///regulation of heart contraction+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0035556///intracellular signal transduction+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002224///toll-like receptor signaling pathway+++GO:1903672///positive regulation of sprouting angiogenesis","S100 calcium binding protein A1","[S10A1_HUMAN|Reviewed]RecName: Full=Protein S100-A1; AltName: Full=S-100 protein alpha chain; AltName: Full=S-100 protein subunit alpha; AltName: Full=S100 calcium-binding protein A1;+++[A0A0S2Z4H2_HUMAN|Unreviewed]RecName: Full=Protein S100 {ECO:0000256|RuleBase:RU361184}; AltName: Full=S100 calcium-binding protein {ECO:0000256|RuleBase:RU361184}; Flags: Fragment;+++[Q5T7Y4_HUMAN|Unreviewed]SubName: Full=Protein S100-A1 {ECO:0000313|Ensembl:ENSP00000357685}; SubName: Full=S100 calcium binding protein A1 isoform 2 {ECO:0000313|EMBL:ALQ33776.1};+++[Q5T7Y5_HUMAN|Unreviewed]SubName: Full=Protein S100-A1 {ECO:0000313|Ensembl:ENSP00000389708}; Flags: Fragment;+++[Q5T7Y6_HUMAN|Unreviewed]RecName: Full=Protein S100 {ECO:0000256|RuleBase:RU361184}; AltName: Full=S100 calcium-binding protein {ECO:0000256|RuleBase:RU361184};"]
[6277,"'S100A6'",3846,5160,4096,4367.33333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0001726///ruffle+++GO:0062023///collagen-containing extracellular matrix+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005635///nuclear envelope+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005576///extracellular region","GO:0042803///protein homodimerization activity+++GO:0044548///S100 protein binding+++GO:0005515///protein binding+++GO:0005523///tropomyosin binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005509///calcium ion binding+++GO:0015075///ion transmembrane transporter activity+++GO:0048306///calcium-dependent protein binding","GO:0007165///signal transduction+++GO:0007409///axonogenesis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0034220///ion transmembrane transport","S100 calcium binding protein A6","[S10A6_HUMAN|Reviewed]RecName: Full=Protein S100-A6; AltName: Full=Calcyclin; AltName: Full=Growth factor-inducible protein 2A9; AltName: Full=MLN 4; AltName: Full=Prolactin receptor-associated protein; Short=PRA; AltName: Full=S100 calcium-binding protein A6;+++[R4GN98_HUMAN|Unreviewed]RecName: Full=Protein S100 {ECO:0000256|RuleBase:RU361184}; AltName: Full=S100 calcium-binding protein {ECO:0000256|RuleBase:RU361184}; Flags: Fragment;"]
[6311,"'ATXN2'",1995,2134,1989,2039.33333333333,"04137///Mitophagy - animal+++04014///Ras signaling pathway+++04140///Autophagy - animal+++04722///Neurotrophin signaling pathway","H00408///Type I diabetes mellitus",null,null,"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005802///trans-Golgi network+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:0010494///cytoplasmic stress granule+++GO:0048471///perinuclear region of cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0005154///epidermal growth factor receptor binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0002091///negative regulation of receptor internalization+++GO:0006417///regulation of translation+++GO:0034063///stress granule assembly+++GO:0016070///RNA metabolic process+++GO:0010603///regulation of cytoplasmic mRNA processing body assembly+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0050658///RNA transport","ataxin 2","[ATX2_HUMAN|Reviewed]RecName: Full=Ataxin-2; AltName: Full=Spinocerebellar ataxia type 2 protein; AltName: Full=Trinucleotide repeat-containing gene 13 protein;+++[A0A2R8Y5A6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000494663};+++[A0A2R8Y6W7_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000495833}; Flags: Fragment;+++[A0A2R8Y7E6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000496055}; Flags: Fragment;+++[A0A2R8Y7P6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000496279};+++[A0A2R8YCG6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000493566}; Flags: Fragment;+++[A0A2R8YDM9_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000493897};+++[A0A2R8YGV1_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000496329}; Flags: Fragment;+++[F8VQP2_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000445583};+++[F8VRK6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000448640}; Flags: Fragment;+++[F8VVY6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000449566}; Flags: Fragment;+++[F8VZC1_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000447741}; Flags: Fragment;+++[F8W0B5_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000447225}; Flags: Fragment;+++[F8WB05_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000373806}; Flags: Fragment;+++[F8WB06_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000373805}; Flags: Fragment;+++[H0YH87_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000446512};+++[Q2M2R5_HUMAN|Unreviewed]SubName: Full=ATXN2 protein {ECO:0000313|EMBL:AAI11758.1}; Flags: Fragment;+++[S4R3J6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000474442}; Flags: Fragment;+++[S4R3R6_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000474645}; Flags: Fragment;+++[V9GY86_HUMAN|Unreviewed]SubName: Full=Ataxin-2 {ECO:0000313|Ensembl:ENSP00000476504};"]
[6326,"'SCN2A'",61,28,27,38.6666666666667,"04742///Taste transduction","H00606///Early infantile epileptic encephalopathy+++H00806///Benign familial neonatal and infantile epilepsies",null,null,"GO:0033270///paranode region of axon+++GO:0005887///integral component of plasma membrane+++GO:0034706///sodium channel complex+++GO:0099056///integral component of presynaptic membrane+++GO:0030315///T-tubule+++GO:0016020///membrane+++GO:0033268///node of Ranvier+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0014704///intercalated disc+++GO:0031226///intrinsic component of plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0001518///voltage-gated sodium channel complex+++GO:0005886///plasma membrane","GO:0005248///voltage-gated sodium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005216///ion channel activity+++GO:0005272///sodium channel activity","GO:0019228///neuronal action potential+++GO:0008627///intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:0035725///sodium ion transmembrane transport+++GO:0051402///neuron apoptotic process+++GO:0006814///sodium ion transport+++GO:0055085///transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0007399///nervous system development+++GO:0086010///membrane depolarization during action potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0042552///myelination+++GO:0006811///ion transport","sodium voltage-gated channel alpha subunit 2","[SCN2A_HUMAN|Reviewed]RecName: Full=Sodium channel protein type 2 subunit alpha; AltName: Full=HBSC II; AltName: Full=Sodium channel protein brain II subunit alpha; AltName: Full=Sodium channel protein type II subunit alpha; AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.2;+++[A0A0D9SGG2_HUMAN|Unreviewed]SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|Ensembl:ENSP00000487466}; Flags: Fragment;+++[A0A1B0GTS6_HUMAN|Unreviewed]SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|Ensembl:ENSP00000489821};+++[A0A1B0GTX0_HUMAN|Unreviewed]SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|Ensembl:ENSP00000489873};+++[A0A1B0GW40_HUMAN|Unreviewed]SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|Ensembl:ENSP00000490765};+++[A0A1B0GW67_HUMAN|Unreviewed]SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|Ensembl:ENSP00000490800};+++[A0A1B0GWA6_HUMAN|Unreviewed]RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};+++[D3DPB6_HUMAN|Unreviewed]SubName: Full=Sodium channel, voltage-gated, type II, alpha 2, isoform CRA_a {ECO:0000313|EMBL:EAX11329.1};+++[F6U291_HUMAN|Unreviewed]SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|Ensembl:ENSP00000406454}; Flags: Fragment;"]
[637,"'BID'",292,287,273,284,"04650///Natural killer cell mediated cytotoxicity+++04215///Apoptosis - multiple species+++05416///Viral myocarditis+++05163///Human cytomegalovirus infection+++04210///Apoptosis+++05152///Tuberculosis+++04217///Necroptosis+++04071///Sphingolipid signaling pathway+++01524///Platinum drug resistance+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04115///p53 signaling pathway+++05200///Pathways in cancer+++05010///Alzheimer's disease+++05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0031966///mitochondrial membrane+++GO:0005737///cytoplasm","GO:0005123///death receptor binding+++GO:0046982///protein heterodimerization activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0051402///neuron apoptotic process+++GO:0097284///hepatocyte apoptotic process+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0042127///regulation of cell proliferation+++GO:1902108///regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0090150///establishment of protein localization to membrane+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0001836///release of cytochrome c from mitochondria+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0032461///positive regulation of protein oligomerization+++GO:0006626///protein targeting to mitochondrion+++GO:0008637///apoptotic mitochondrial changes+++GO:0042770///signal transduction in response to DNA damage+++GO:0032459///regulation of protein oligomerization+++GO:0043065///positive regulation of apoptotic process+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0043066///negative regulation of apoptotic process+++GO:0051260///protein homooligomerization+++GO:0042981///regulation of apoptotic process+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0032464///positive regulation of protein homooligomerization+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway","BH3 interacting domain death agonist","[BID_HUMAN|Reviewed]RecName: Full=BH3-interacting domain death agonist; AltName: Full=p22 BID; Short=BID; Contains: RecName: Full=BH3-interacting domain death agonist p15; AltName: Full=p15 BID; Contains: RecName: Full=BH3-interacting domain death agonist p13; AltName: Full=p13 BID; Contains: RecName: Full=BH3-interacting domain death agonist p11; AltName: Full=p11 BID;+++[A0A2P1N6T5_HUMAN|Unreviewed]SubName: Full=BH3 interacting domain death agonist Si6 isoform {ECO:0000313|EMBL:AVP50014.1}; Flags: Fragment;+++[A0A2P1N6U0_HUMAN|Unreviewed]SubName: Full=BH3 interacting domain death agonist Si6 isoform {ECO:0000313|EMBL:AVP50013.1}; Flags: Fragment;+++[A0A2U9F3W7_HUMAN|Unreviewed]SubName: Full=BID isoform Si6 {ECO:0000313|EMBL:AWQ38328.1}; Flags: Fragment;+++[A8ASI8_HUMAN|Unreviewed]SubName: Full=BH3 interacting domain death agonist, isoform CRA_d {ECO:0000313|EMBL:EAW57773.1}; SubName: Full=BID isoform L(2) {ECO:0000313|EMBL:ACD47108.1}; SubName: Full=Desmocollin type 4 {ECO:0000313|EMBL:BAF79673.1}; SubName: Full=cDNA, FLJ94329, Homo sapiens BH3 interacting domain death agonist (BID), mRNA {ECO:0000313|EMBL:BAG36471.1};+++[B2ZP78_HUMAN|Unreviewed]SubName: Full=BH3-interacting domain death agonist {ECO:0000313|Ensembl:ENSP00000481991}; SubName: Full=BID isoform Si6 {ECO:0000313|EMBL:ACD47106.1};+++[B2ZP79_HUMAN|Unreviewed]SubName: Full=BH3 interacting domain death agonist, isoform CRA_b {ECO:0000313|EMBL:EAW57771.1}; SubName: Full=BID isoform ES(1b) {ECO:0000313|EMBL:ACD47107.1};+++[B3KT21_HUMAN|Unreviewed]SubName: Full=cDNA FLJ37476 fis, clone BRAWH2012827, highly similar to Homo sapiens BH3 interacting domain death agonist (BID), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG52933.1};"]
[63826,"'SRR'",198.07,162.65,227.84,196.186666666667,"01100///Metabolic pathways+++00260///Glycine, serine and threonine metabolism",null,null,"R00589///serine racemase; L-2-Amino-3-hydroxypropionic   L-Serine <=> D-Serine","GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0045177///apical part of cell+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0018114///threonine racemase activity+++GO:0046872///metal ion binding+++GO:0008721///D-serine ammonia-lyase activity+++GO:0000287///magnesium ion binding+++GO:0016829///lyase activity+++GO:0000166///nucleotide binding+++GO:0042803///protein homodimerization activity+++GO:0003824///catalytic activity+++GO:0005509///calcium ion binding+++GO:0030165///PDZ domain binding+++GO:0016594///glycine binding+++GO:0030378///serine racemase activity+++GO:0005524///ATP binding+++GO:0030170///pyridoxal phosphate binding+++GO:0003941///L-serine ammonia-lyase activity+++GO:0016853///isomerase activity","GO:0051289///protein homotetramerization+++GO:0042493///response to drug+++GO:0006564///L-serine biosynthetic process+++GO:0043278///response to morphine+++GO:0014070///response to organic cyclic compound+++GO:0006563///L-serine metabolic process+++GO:0007568///aging+++GO:0008152///metabolic process+++GO:0070179///D-serine biosynthetic process+++GO:0070178///D-serine metabolic process+++GO:0032496///response to lipopolysaccharide+++GO:0042866///pyruvate biosynthetic process+++GO:0007420///brain development+++GO:0006520///cellular amino acid metabolic process+++GO:0009069///serine family amino acid metabolic process","serine racemase","[SRR_HUMAN|Reviewed]RecName: Full=Serine racemase {ECO:0000303|PubMed:11054547}; EC=5.1.1.18 {ECO:0000269|PubMed:20106978}; AltName: Full=D-serine ammonia-lyase; AltName: Full=D-serine dehydratase; EC=4.3.1.18 {ECO:0000250|UniProtKB:Q9QZX7}; AltName: Full=L-serine ammonia-lyase; AltName: Full=L-serine dehydratase; EC=4.3.1.17 {ECO:0000250|UniProtKB:Q9QZX7};+++[I3L3N0_HUMAN|Unreviewed]SubName: Full=Serine racemase {ECO:0000313|Ensembl:ENSP00000460581}; Flags: Fragment;+++[I3L4B4_HUMAN|Unreviewed]SubName: Full=Serine racemase {ECO:0000313|Ensembl:ENSP00000461125}; Flags: Fragment;+++[I3L4L3_HUMAN|Unreviewed]SubName: Full=Serine racemase {ECO:0000313|Ensembl:ENSP00000461343}; Flags: Fragment;+++[I3L4W4_HUMAN|Unreviewed]SubName: Full=Serine racemase {ECO:0000313|Ensembl:ENSP00000461589}; Flags: Fragment;+++[Q3ZK31_HUMAN|Unreviewed]SubName: Full=Serine racemase {ECO:0000313|EMBL:AAW66461.1, ECO:0000313|Ensembl:ENSP00000458814}; Flags: Fragment;+++[Q8N3F4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp762A2415 {ECO:0000313|EMBL:CAD39041.1}; Flags: Fragment;+++[V9GYE8_HUMAN|Unreviewed]SubName: Full=Serine racemase {ECO:0000313|Ensembl:ENSP00000476682};"]
[63906,"'GPATCH3'",183,219,149,183.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0032480///negative regulation of type I interferon production+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0039536///negative regulation of RIG-I signaling pathway","G-patch domain containing 3","[GPTC3_HUMAN|Reviewed]RecName: Full=G patch domain-containing protein 3;+++[H0Y5H5_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000398563}; Flags: Fragment;+++[Q5JYG5_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000399036}; Flags: Fragment;"]
[63922,"'CHTF18'",163,137,134,144.666666666667,{"$nulls":4},"GO:0031390///Ctf18 RFC-like complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0003689///DNA clamp loader activity+++GO:0043142///single-stranded DNA-dependent ATPase activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0004386///helicase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:1900264///positive regulation of DNA-directed DNA polymerase activity+++GO:0006260///DNA replication+++GO:0007049///cell cycle","chromosome transmission fidelity factor 18","[CTF18_HUMAN|Reviewed]RecName: Full=Chromosome transmission fidelity protein 18 homolog; Short=hCTF18; AltName: Full=CHL12;+++[A0A0D9SF58_HUMAN|Unreviewed]SubName: Full=Chromosome transmission fidelity protein 18 homolog {ECO:0000313|Ensembl:ENSP00000486314};+++[E7EXA6_HUMAN|Unreviewed]SubName: Full=Chromosome transmission fidelity protein 18 homolog {ECO:0000313|Ensembl:ENSP00000313029};+++[F8WCC1_HUMAN|Unreviewed]SubName: Full=Chromosome transmission fidelity protein 18 homolog {ECO:0000313|Ensembl:ENSP00000399111};+++[H0Y7D3_HUMAN|Unreviewed]SubName: Full=Chromosome transmission fidelity protein 18 homolog {ECO:0000313|Ensembl:ENSP00000412015}; Flags: Fragment;+++[H3BN43_HUMAN|Unreviewed]SubName: Full=Chromosome transmission fidelity protein 18 homolog {ECO:0000313|Ensembl:ENSP00000454679}; Flags: Fragment;+++[H3BT35_HUMAN|Unreviewed]SubName: Full=Chromosome transmission fidelity protein 18 homolog {ECO:0000313|Ensembl:ENSP00000456998};+++[Q96S08_HUMAN|Unreviewed]SubName: Full=Some homology with holliday junction DNA helicase RUVB like {ECO:0000313|EMBL:AAK61256.1};"]
[63971,"'KIF13A'",2497,1807,2031,2111.66666666667,{"$nulls":4},"GO:0005813///centrosome+++GO:0010008///endosome membrane+++GO:0005871///kinesin complex+++GO:0005623///cell+++GO:0016020///membrane+++GO:0005874///microtubule+++GO:0032588///trans-Golgi network membrane+++GO:0005815///microtubule organizing center+++GO:0030496///midbody+++GO:0005794///Golgi apparatus+++GO:0005768///endosome+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0003774///motor activity+++GO:0016887///ATPase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0003777///microtubule motor activity+++GO:0000166///nucleotide binding","GO:0032438///melanosome organization+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0072383///plus-end-directed vesicle transport along microtubule+++GO:0051301///cell division+++GO:0035459///cargo loading into vesicle+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0032465///regulation of cytokinesis+++GO:0007049///cell cycle+++GO:0008333///endosome to lysosome transport+++GO:0007018///microtubule-based movement","kinesin family member 13A","[KI13A_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF13A; AltName: Full=Kinesin-like protein RBKIN;+++[A0A1B0GUA8_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF13A {ECO:0000313|Ensembl:ENSP00000490031};+++[H0Y307_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF13A {ECO:0000313|Ensembl:ENSP00000351150}; Flags: Fragment;+++[H0Y925_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF13A {ECO:0000313|Ensembl:ENSP00000422808}; Flags: Fragment;+++[H0Y9Z7_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF13A {ECO:0000313|Ensembl:ENSP00000425616}; Flags: Fragment;"]
[6404,"'SELPLG'",117,115,92,108,"05150///Staphylococcus aureus infection+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0001931///uropod+++GO:0016021///integral component of membrane+++GO:0044853///plasma membrane raft+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0001618///virus receptor activity+++GO:0005102///signaling receptor binding","GO:0046718///viral entry into host cell+++GO:0016032///viral process+++GO:0050901///leukocyte tethering or rolling+++GO:0050900///leukocyte migration+++GO:0050902///leukocyte adhesive activation+++GO:0071354///cellular response to interleukin-6+++GO:0007155///cell adhesion","selectin P ligand","[SELPL_HUMAN|Reviewed]RecName: Full=P-selectin glycoprotein ligand 1; Short=PSGL-1; AltName: Full=Selectin P ligand; AltName: CD_antigen=CD162; Flags: Precursor;+++[A0A0C4DFY0_HUMAN|Unreviewed]SubName: Full=P-selectin glycoprotein ligand 1 {ECO:0000313|Ensembl:ENSP00000373614};"]
[64065,"'PERP'",1085,1130,1015,1076.66666666667,"04115///p53 signaling pathway",{"$nulls":3},"GO:0030057///desmosome+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005739///mitochondrion",null,"GO:0007155///cell adhesion+++GO:0070268///cornification+++GO:0097186///amelogenesis+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0002934///desmosome organization+++GO:0045862///positive regulation of proteolysis+++GO:0007219///Notch signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0034113///heterotypic cell-cell adhesion+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0006915///apoptotic process","PERP, TP53 apoptosis effector","[PERP_HUMAN|Reviewed]RecName: Full=p53 apoptosis effector related to PMP-22; AltName: Full=Keratinocyte-associated protein 1; Short=KCP-1; AltName: Full=P53-induced protein PIGPC1; AltName: Full=Transmembrane protein THW;"]
[64115,"'VSIR'",2123,2539,2161,2274.33333333333,null,"H01705///Bilateral sudden sensorineural hearing loss+++H00779///Usher syndrome (US)+++H00605///Deafness, autosomal recessive",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding+++GO:0061133///endopeptidase activator activity+++GO:0019899///enzyme binding","GO:0032689///negative regulation of interferon-gamma production+++GO:0120158///positive regulation of collagen catabolic process+++GO:0030335///positive regulation of cell migration+++GO:2000562///negative regulation of CD4-positive, alpha-beta T cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0031638///zymogen activation+++GO:2000565///negative regulation of CD8-positive, alpha-beta T cell proliferation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0032693///negative regulation of interleukin-10 production+++GO:0032700///negative regulation of interleukin-17 production+++GO:0010950///positive regulation of endopeptidase activity+++GO:0045591///positive regulation of regulatory T cell differentiation","V-set immunoregulatory receptor","[VISTA_HUMAN|Reviewed]RecName: Full=V-type immunoglobulin domain-containing suppressor of T-cell activation {ECO:0000303|PubMed:24691993}; AltName: Full=Platelet receptor Gi24 {ECO:0000303|Ref.1}; AltName: Full=Stress-induced secreted protein-1 {ECO:0000303|Ref.2}; Short=Sisp-1 {ECO:0000303|Ref.2}; AltName: Full=V-set domain-containing immunoregulatory receptor {ECO:0000250|UniProtKB:Q9D659}; AltName: Full=V-set immunoregulatory receptor {ECO:0000312|HGNC:HGNC:30085}; Flags: Precursor;+++[Q2TA85_HUMAN|Unreviewed]SubName: Full=C10orf54 protein {ECO:0000313|EMBL:AAI11049.1}; Flags: Fragment;+++[Q8WYG9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PP2135 {ECO:0000313|EMBL:AAG22476.1};"]
[64123,"'ADGRL4'",6,6,3,5,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane","GO:0005509///calcium ion binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0046983///protein dimerization activity+++GO:0004930///G protein-coupled receptor activity","GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007166///cell surface receptor signaling pathway","adhesion G protein-coupled receptor L4","[AGRL4_HUMAN|Reviewed]RecName: Full=Adhesion G protein-coupled receptor L4 {ECO:0000303|PubMed:25713288}; AltName: Full=EGF, latrophilin and seven transmembrane domain-containing protein 1; AltName: Full=EGF-TM7-latrophilin-related protein; Short=ETL protein; Flags: Precursor;+++[A0A1W2PP07_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor L4 {ECO:0000313|Ensembl:ENSP00000491199};+++[B1AR72_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor L4 {ECO:0000313|Ensembl:ENSP00000383813}; Flags: Fragment;+++[L8EB43_HUMAN|Unreviewed]SubName: Full=Alternative protein ELTD1 {ECO:0000313|EMBL:CCQ43683.1};"]
[6415,"'SELENOW'",2517,3086,3220,2941,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016209///antioxidant activity","GO:0010269///response to selenium ion+++GO:0098869///cellular oxidant detoxification","selenoprotein W","[SELW_HUMAN|Reviewed]RecName: Full=Selenoprotein W {ECO:0000303|PubMed:27645994, ECO:0000303|PubMed:9256076}; Short=SelW {ECO:0000303|PubMed:27645994};+++[A0A024R0V8_HUMAN|Unreviewed]SubName: Full=Selenoprotein W, 1 {ECO:0000313|EMBL:EAW57513.1}; Flags: Fragment;+++[A0A087WX02_HUMAN|Unreviewed]SubName: Full=Selenoprotein W {ECO:0000313|Ensembl:ENSP00000480640};+++[F8WB74_HUMAN|Unreviewed]SubName: Full=Selenoprotein W {ECO:0000313|Ensembl:ENSP00000422644};+++[M0QYX1_HUMAN|Unreviewed]SubName: Full=Selenoprotein W {ECO:0000313|Ensembl:ENSP00000470135};"]
[6423,"'SFRP2'",705,675,410,596.666666666667,"04310///Wnt signaling pathway",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0001968///fibronectin binding+++GO:0008047///enzyme activator activity+++GO:0017147///Wnt-protein binding+++GO:0005178///integrin binding+++GO:0061133///endopeptidase activator activity+++GO:0048018///receptor ligand activity","GO:0030154///cell differentiation+++GO:0003214///cardiac left ventricle morphogenesis+++GO:0071481///cellular response to X-ray+++GO:0043508///negative regulation of JUN kinase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031668///cellular response to extracellular stimulus+++GO:0009952///anterior/posterior pattern specification+++GO:0061056///sclerotome development+++GO:0090175///regulation of establishment of planar polarity+++GO:0010975///regulation of neuron projection development+++GO:0043065///positive regulation of apoptotic process+++GO:0046546///development of primary male sexual characteristics+++GO:0010950///positive regulation of endopeptidase activity+++GO:0071425///hematopoietic stem cell proliferation+++GO:0007584///response to nutrient+++GO:0030307///positive regulation of cell growth+++GO:0016055///Wnt signaling pathway+++GO:0036342///post-anal tail morphogenesis+++GO:0060028///convergent extension involved in axis elongation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0010469///regulation of signaling receptor activity+++GO:2000041///negative regulation of planar cell polarity pathway involved in axis elongation+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042733///embryonic digit morphogenesis+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0042981///regulation of apoptotic process+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0003151///outflow tract morphogenesis+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0007275///multicellular organism development+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0060070///canonical Wnt signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:2000035///regulation of stem cell division+++GO:1904956///regulation of midbrain dopaminergic neuron differentiation+++GO:0008584///male gonad development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030336///negative regulation of cell migration+++GO:0002063///chondrocyte development+++GO:0030199///collagen fibril organization+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0042662///negative regulation of mesodermal cell fate specification+++GO:0030111///regulation of Wnt signaling pathway+++GO:0007267///cell-cell signaling+++GO:0021915///neural tube development+++GO:0001756///somitogenesis+++GO:0061185///negative regulation of dermatome development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0042493///response to drug+++GO:0010629///negative regulation of gene expression+++GO:0090179///planar cell polarity pathway involved in neural tube closure+++GO:0001843///neural tube closure+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0090244///Wnt signaling pathway involved in somitogenesis+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0051216///cartilage development+++GO:0060349///bone morphogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0006915///apoptotic process+++GO:0048546///digestive tract morphogenesis","secreted frizzled related protein 2","[SFRP2_HUMAN|Reviewed]RecName: Full=Secreted frizzled-related protein 2; Short=FRP-2; Short=sFRP-2; AltName: Full=Secreted apoptosis-related protein 1; Short=SARP-1; Flags: Precursor;+++[A0A140VJU3_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 170 {ECO:0000313|EMBL:AEE61080.1};+++[B3KSM5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36603 fis, clone TRACH2015180, highly similar to Secreted frizzled-related protein 2 {ECO:0000313|EMBL:BAG52787.1};"]
[64241,"'ABCG8'",0,0,1,0.333333333333333,"04979///Cholesterol metabolism+++04975///Fat digestion and absorption+++04976///Bile secretion+++02010///ABC transporters","H00152///Sitosterolemia+++H01740///Macrothrombocytopenia+++H01213///Gallbladder disease",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0043235///receptor complex","GO:0046982///protein heterodimerization activity+++GO:0017127///cholesterol transporter activity+++GO:0005515///protein binding+++GO:0015248///sterol transporter activity+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity+++GO:0005524///ATP binding+++GO:0015238///drug transmembrane transporter activity+++GO:0046872///metal ion binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances","GO:0006869///lipid transport+++GO:0042632///cholesterol homeostasis+++GO:0042493///response to drug+++GO:0007584///response to nutrient+++GO:0015918///sterol transport+++GO:0030299///intestinal cholesterol absorption+++GO:0055092///sterol homeostasis+++GO:0007588///excretion+++GO:0055085///transmembrane transport+++GO:0033344///cholesterol efflux+++GO:0006855///drug transmembrane transport+++GO:0045796///negative regulation of intestinal cholesterol absorption+++GO:0010949///negative regulation of intestinal phytosterol absorption+++GO:0015914///phospholipid transport","ATP binding cassette subfamily G member 8","[ABCG8_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family G member 8; AltName: Full=Sterolin-2 {ECO:0000303|PubMed:11452359};+++[A0A2R8Y6M1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family G member 8 {ECO:0000313|Ensembl:ENSP00000495423}; Flags: Fragment;+++[B7ZL41_HUMAN|Unreviewed]SubName: Full=ABCG8 protein {ECO:0000313|EMBL:AAI43565.1};+++[Q14CR0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family G (WHITE), member 8 {ECO:0000313|EMBL:AAI13658.1};+++[Q96A01_HUMAN|Unreviewed]SubName: Full=Sterolin 2 {ECO:0000313|EMBL:AAK85386.1}; Flags: Fragment;"]
[64283,"'ARHGEF28'",583,516,552,550.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0048013///ephrin receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0035023///regulation of Rho protein signal transduction+++GO:0030154///cell differentiation","Rho guanine nucleotide exchange factor 28","[ARG28_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 28; AltName: Full=190 kDa guanine nucleotide exchange factor; Short=p190-RhoGEF; Short=p190RhoGEF; AltName: Full=Rho guanine nucleotide exchange factor;+++[A0A2X0U2G7_HUMAN|Unreviewed]SubName: Full=ARHGEF28 {ECO:0000313|EMBL:SPT35731.1}; Flags: Fragment;+++[D6RAP0_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 28 {ECO:0000313|Ensembl:ENSP00000421859}; Flags: Fragment;+++[D6RGZ3_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 28 {ECO:0000313|Ensembl:ENSP00000421081};"]
[64326,"'COP1'",347,333,330,336.666666666667,"04115///p53 signaling pathway+++04712///Circadian rhythm - plant+++04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0000139///Golgi membrane+++GO:0010494///cytoplasmic stress granule+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0008270///zinc ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0070628///proteasome binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding","GO:0010212///response to ionizing radiation+++GO:0035617///stress granule disassembly+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090316///positive regulation of intracellular protein transport+++GO:1903843///cellular response to arsenite ion+++GO:0043687///post-translational protein modification+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0032197///transposition, RNA-mediated+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition","COP1, E3 ubiquitin ligase","[COP1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase COP1 {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:12615916}; AltName: Full=Constitutive photomorphogenesis protein 1 homolog {ECO:0000303|PubMed:12466024}; Short=hCOP1 {ECO:0000303|PubMed:12466024}; AltName: Full=RING finger and WD repeat domain protein 2 {ECO:0000305}; AltName: Full=RING finger protein 200; AltName: Full=RING-type E3 ubiquitin transferase RFWD2 {ECO:0000305};+++[Q05CT6_HUMAN|Unreviewed]SubName: Full=RFWD2 protein {ECO:0000313|EMBL:AAH20845.1}; Flags: Fragment;+++[X5D2S9_HUMAN|Unreviewed]SubName: Full=Ring finger and WD repeat domain 2 isoform F {ECO:0000313|EMBL:AHW56569.1}; Flags: Fragment;+++[X5D7N8_HUMAN|Unreviewed]SubName: Full=Ring finger and WD repeat domain 2 isoform C {ECO:0000313|EMBL:AHW56570.1}; Flags: Fragment;+++[X5D7W8_HUMAN|Unreviewed]SubName: Full=Ring finger and WD repeat domain 2 isoform G {ECO:0000313|EMBL:AHW56700.1};+++[X5D9B8_HUMAN|Unreviewed]SubName: Full=Ring finger and WD repeat domain 2 isoform H {ECO:0000313|EMBL:AHW56573.1}; Flags: Fragment;+++[X5DNY7_HUMAN|Unreviewed]SubName: Full=Ring finger and WD repeat domain 2 isoform D {ECO:0000313|EMBL:AHW56571.1}; Flags: Fragment;+++[X5DR91_HUMAN|Unreviewed]SubName: Full=Ring finger and WD repeat domain 2 isoform B {ECO:0000313|EMBL:AHW56572.1}; Flags: Fragment;+++[X5DRD4_HUMAN|Unreviewed]SubName: Full=Ring finger and WD repeat domain 2 isoform I {ECO:0000313|EMBL:AHW56632.1};"]
[643596,"'RNF224'",6,10,8,8,"04928///Parathyroid hormone synthesis, secretion and action","H01298///Pulmonary alveolar microlithiasis (PALM)+++H02138///Hereditary hypophophatemic rickets with hypercalciuria+++H01198///Fanconi renotubular syndrome (FTS)+++H00214///Hypophosphatemic rickets+++H00888///Nephrolithiasis/osteoporosis, hypophosphatemic",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding","GO:0051865///protein autoubiquitination","ring finger protein 224","[RN224_HUMAN|Reviewed]RecName: Full=RING finger protein 224;"]
[6439,"'SFTPB'",3,1,2,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0097486///multivesicular body lumen+++GO:0005615///extracellular space+++GO:0005789///endoplasmic reticulum membrane+++GO:0005771///multivesicular body+++GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0097208///alveolar lamellar body+++GO:0042599///lamellar body+++GO:0005764///lysosome","GO:0008047///enzyme activator activity+++GO:0001664///G protein-coupled receptor binding","GO:0009887///animal organ morphogenesis+++GO:0044267///cellular protein metabolic process+++GO:0007585///respiratory gaseous exchange+++GO:0006629///lipid metabolic process+++GO:0006665///sphingolipid metabolic process","surfactant protein B","[PSPB_HUMAN|Reviewed]RecName: Full=Pulmonary surfactant-associated protein B; Short=SP-B; AltName: Full=18 kDa pulmonary-surfactant protein; AltName: Full=6 kDa protein; AltName: Full=Pulmonary surfactant-associated proteolipid SPL(Phe); Flags: Precursor;+++[D6W5L6_HUMAN|Unreviewed]SubName: Full=Pulmonary surfactant-associated protein B {ECO:0000313|Ensembl:ENSP00000386346}; SubName: Full=Surfactant, pulmonary-associated protein B, isoform CRA_a {ECO:0000313|EMBL:EAW99488.1};+++[H0Y7V6_HUMAN|Unreviewed]SubName: Full=Pulmonary surfactant-associated protein B {ECO:0000313|Ensembl:ENSP00000415347}; Flags: Fragment;+++[U3KQT2_HUMAN|Unreviewed]SubName: Full=Pulmonary surfactant-associated protein B {ECO:0000313|Ensembl:ENSP00000476194}; Flags: Fragment;"]
[644096,"'SDHAF1'",145,145,142,144,null,"H02005///Mitochondrial complex II deficiency",null,null,"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0034553///mitochondrial respiratory chain complex II assembly","succinate dehydrogenase complex assembly factor 1","[SDHF1_HUMAN|Reviewed]RecName: Full=Succinate dehydrogenase assembly factor 1, mitochondrial {ECO:0000303|PubMed:19465911}; Short=SDH assembly factor 1 {ECO:0000303|PubMed:19465911}; Short=SDHAF1 {ECO:0000303|PubMed:19465911}; AltName: Full=LYR motif-containing protein 8;"]
[64423,"'INF2'",4074,3869,3956,3966.33333333333,"00250///Alanine, aspartate and glutamate metabolism+++01100///Metabolic pathways+++00230///Purine metabolism","H00594///Distal myopathy","M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R01135///IMP:L-aspartate ligase (GDP-forming) GTP + IMP + L-Aspartate <=> GDP + Orthophosphate + N6-(1,2-Dicarboxyethyl)-AMP","GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0003779///actin binding+++GO:0017048///Rho GTPase binding","GO:0090140///regulation of mitochondrial fission+++GO:0016043///cellular component organization+++GO:0030036///actin cytoskeleton organization","inverted formin, FH2 and WH2 domain containing","[INF2_HUMAN|Reviewed]RecName: Full=Inverted formin-2; AltName: Full=HBEBP2-binding protein C;+++[A0A0A0MQU1_HUMAN|Unreviewed]SubName: Full=Inverted formin-2 {ECO:0000313|Ensembl:ENSP00000252527}; Flags: Fragment;+++[Q8WYS3_HUMAN|Unreviewed]SubName: Full=Inverted formin-2 {ECO:0000313|Ensembl:ENSP00000483829};"]
[644596,"'SMIM10L2B'",164,198,186,182.666666666667,{"$nulls":7},"small integral membrane protein 10 like 2B","[SIL2A_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 2A {ECO:0000305};+++[SIL2B_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 2B {ECO:0000305};"]
[64506,"'CPEB1'",117,143,128,129.333333333333,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis+++04320///Dorso-ventral axis formation",{"$nulls":3},"GO:1990124///messenger ribonucleoprotein complex+++GO:0014069///postsynaptic density+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0005654///nucleoplasm+++GO:0045211///postsynaptic membrane+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0000932///P-body+++GO:0043005///neuron projection+++GO:0005634///nucleus","GO:0043022///ribosome binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0045182///translation regulator activity+++GO:0005515///protein binding+++GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0046872///metal ion binding+++GO:0008135///translation factor activity, RNA binding","GO:0006397///mRNA processing+++GO:0071456///cellular response to hypoxia+++GO:1900365///positive regulation of mRNA polyadenylation+++GO:0032869///cellular response to insulin stimulus+++GO:0006412///translation+++GO:2000766///negative regulation of cytoplasmic translation+++GO:0071230///cellular response to amino acid stimulus+++GO:0006417///regulation of translation","cytoplasmic polyadenylation element binding protein 1","[CPEB1_HUMAN|Reviewed]RecName: Full=Cytoplasmic polyadenylation element-binding protein 1; Short=CPE-BP1; Short=CPE-binding protein 1; Short=h-CPEB; Short=hCPEB-1;+++[A0A024R214_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element binding protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW62452.1}; SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000478598};+++[A0A087WUQ9_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000478841};+++[A0A087WVR7_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000479625};+++[A0A087WXG7_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000481010};+++[A0A087X171_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000483951};+++[A0A0J9YX15_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000488206};+++[A0A0J9YXP0_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000488484}; Flags: Fragment;+++[B4DWY2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50904, highly similar to Homo sapiens cytoplasmic polyadenylation element binding protein 1 (CPEB1), mRNA {ECO:0000313|EMBL:BAG63194.1};+++[E1CJT3_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element binding protein 4 variant {ECO:0000313|EMBL:BAJ19018.1};+++[H3BNX1_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000455044}; Flags: Fragment;+++[H3BPD6_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000455268}; Flags: Fragment;+++[H3BTE4_HUMAN|Unreviewed]SubName: Full=Cytoplasmic polyadenylation element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000457137}; Flags: Fragment;"]
[64598,"'MOSPD3'",528,697,584,603,{"$nulls":4},"GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane",null,"GO:0007507///heart development","motile sperm domain containing 3","[MSPD3_HUMAN|Reviewed]RecName: Full=Motile sperm domain-containing protein 3;+++[C9J3M4_HUMAN|Unreviewed]SubName: Full=Motile sperm domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000417276}; Flags: Fragment;+++[F8WF07_HUMAN|Unreviewed]SubName: Full=Motile sperm domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000419535};"]
[646588,"'LOC646588'",22,32,39,31,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus+++GO:0010494///cytoplasmic stress granule","GO:0003964///RNA-directed DNA polymerase activity+++GO:0051213///dioxygenase activity+++GO:0000166///nucleotide binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003727///single-stranded RNA binding+++GO:0003697///single-stranded DNA binding+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0042802///identical protein binding","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0010468///regulation of gene expression","uncharacterized LOC646588","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF1_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein {ECO:0000305}; Short=L1-ORF1p {ECO:0000303|PubMed:28806172}; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1; AltName: Full=Transposase element L1Md-A101/L1Md-A102/L1Md-A2;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PO22_POPJA|diamond]RecName: Full=Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2; AltName: Full=Retrovirus-related Pol polyprotein from type I retrotransposable element R2; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; Flags: Fragment;+++[POLR_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM; AltName: Full=Retrovirus-related Pol polyprotein from type II retrotransposable element R2DM; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[64714,"'PDIA2'",42,37,24,34.3333333333333,{"$nulls":4},"GO:0005623///cell+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0008289///lipid binding+++GO:0003756///protein disulfide isomerase activity+++GO:0015036///disulfide oxidoreductase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0031545///peptidyl-proline 4-dioxygenase activity+++GO:0005496///steroid binding+++GO:0005515///protein binding","GO:0006457///protein folding+++GO:0019511///peptidyl-proline hydroxylation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0045454///cell redox homeostasis+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0055114///oxidation-reduction process+++GO:0006621///protein retention in ER lumen+++GO:1902175///regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","protein disulfide isomerase family A member 2","[PDIA2_HUMAN|Reviewed]RecName: Full=Protein disulfide-isomerase A2; EC=5.3.4.1; AltName: Full=Pancreas-specific protein disulfide isomerase; Short=PDIp; Flags: Precursor;+++[A4L733_HUMAN|Unreviewed]SubName: Full=Protein disulfide isomerase family A, member 2 variant {ECO:0000313|EMBL:ABO43034.1};+++[H0Y4J5_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A2 {ECO:0000313|Ensembl:ENSP00000392277}; Flags: Fragment;+++[Q4TT65_HUMAN|Unreviewed]SubName: Full=Protein disulfide isomerase family A, member 2 {ECO:0000313|EMBL:CAI95588.1}; SubName: Full=Protein disulfide-isomerase A2 {ECO:0000313|Ensembl:ENSP00000405081}; Flags: Fragment;+++[Q4TT66_HUMAN|Unreviewed]SubName: Full=Protein disulfide isomerase family A, member 2 {ECO:0000313|EMBL:CAI95587.1}; Flags: Fragment;"]
[64747,"'MFSD1'",392,350,365,369,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0055085///transmembrane transport","major facilitator superfamily domain containing 1","[MFSD1_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 1; AltName: Full=Smooth muscle cell-associated protein 4; Short=SMAP-4;+++[C9J5G6_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000418503}; Flags: Fragment;+++[C9JAC3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000418055}; Flags: Fragment;+++[C9JBA3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000417414}; Flags: Fragment;+++[C9JCH3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000420699}; Flags: Fragment;+++[C9JZW5_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000419708}; Flags: Fragment;+++[H7C4F4_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000417163}; Flags: Fragment;+++[H7C593_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000419281};+++[H7C5U3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000420816}; Flags: Fragment;"]
[64773,"'PCED1A'",426,431,611,489.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04138///Autophagy - yeast",{"$nulls":3},"GO:0005764///lysosome+++GO:0005776///autophagosome+++GO:0043025///neuronal cell body+++GO:0055037///recycling endosome+++GO:0031902///late endosome membrane+++GO:0030136///clathrin-coated vesicle+++GO:0005769///early endosome+++GO:0030897///HOPS complex+++GO:0005770///late endosome+++GO:0005765///lysosomal membrane+++GO:0030424///axon","GO:0005515///protein binding","GO:0035542///regulation of SNARE complex assembly+++GO:0032889///regulation of vacuole fusion, non-autophagic+++GO:0008333///endosome to lysosome transport+++GO:0006886///intracellular protein transport+++GO:0007033///vacuole organization+++GO:0097352///autophagosome maturation","PC-esterase domain containing 1A","[PED1A_HUMAN|Reviewed]RecName: Full=PC-esterase domain-containing protein 1A; AltName: Full=Protein FAM113A; AltName: Full=Sarcoma antigen NY-SAR-23;+++[D3DVX4_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 113, member A, isoform CRA_a {ECO:0000313|EMBL:EAX10571.1};+++[S4R3X0_HUMAN|Unreviewed]SubName: Full=PC-esterase domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000474824}; Flags: Fragment;+++[X6RC47_HUMAN|Unreviewed]SubName: Full=PC-esterase domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000388935}; Flags: Fragment;+++[X6RFT7_HUMAN|Unreviewed]SubName: Full=PC-esterase domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000401711}; Flags: Fragment;"]
[64784,"'CRTC3'",435,427,406,422.666666666667,"05166///HTLV-I infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0008140///cAMP response element binding protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050995///negative regulation of lipid catabolic process+++GO:0051289///protein homotetramerization+++GO:0042116///macrophage activation+++GO:0016032///viral process+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0097009///energy homeostasis+++GO:0032793///positive regulation of CREB transcription factor activity","CREB regulated transcription coactivator 3","[CRTC3_HUMAN|Reviewed]RecName: Full=CREB-regulated transcription coactivator 3; AltName: Full=Transducer of regulated cAMP response element-binding protein 3; Short=TORC-3; Short=Transducer of CREB protein 3;+++[H0YK33_HUMAN|Unreviewed]SubName: Full=CREB-regulated transcription coactivator 3 {ECO:0000313|Ensembl:ENSP00000452640};+++[H0YK64_HUMAN|Unreviewed]SubName: Full=CREB-regulated transcription coactivator 3 {ECO:0000313|Ensembl:ENSP00000452676}; Flags: Fragment;+++[Q8TEF4_HUMAN|Unreviewed]SubName: Full=FLJ00243 protein {ECO:0000313|EMBL:BAB84996.1}; Flags: Fragment;"]
[6484,"'ST3GAL4'",1828,1829,2555,2070.66666666667,"01100///Metabolic pathways+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,null,"R06153///CMP-N-acetylneuraminate + Lc4Cer <=> CMP + 3'-isoLM1","GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0032580///Golgi cisterna membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0047288///monosialoganglioside sialyltransferase activity+++GO:0008373///sialyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0006486///protein glycosylation+++GO:0050890///cognition+++GO:0009101///glycoprotein biosynthetic process+++GO:0030259///lipid glycosylation+++GO:1990743///protein sialylation+++GO:0097503///sialylation+++GO:0009312///oligosaccharide biosynthetic process+++GO:0009247///glycolipid biosynthetic process+++GO:0016266///O-glycan processing+++GO:0018146///keratan sulfate biosynthetic process","ST3 beta-galactoside alpha-2,3-sialyltransferase 4","[SIA4C_HUMAN|Reviewed]RecName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; Short=Alpha 2,3-ST 4; Short=Beta-galactoside alpha-2,3-sialyltransferase 4; EC=2.4.99.2 {ECO:0000250|UniProtKB:Q91Y74}; EC=2.4.99.4 {ECO:0000250|UniProtKB:Q91Y74}; AltName: Full=Alpha 2,3-sialyltransferase IV; AltName: Full=Gal-NAc6S; AltName: Full=Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; AltName: Full=SAT-3; AltName: Full=ST-4; AltName: Full=ST3Gal IV; Short=ST3GalIV; AltName: Full=ST3GalA.2; AltName: Full=STZ; AltName: Full=Sialyltransferase 4C; Short=SIAT4-C;+++[E9PKJ2_HUMAN|Unreviewed]SubName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 {ECO:0000313|Ensembl:ENSP00000433495};+++[E9PMC7_HUMAN|Unreviewed]SubName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 {ECO:0000313|Ensembl:ENSP00000431170}; Flags: Fragment;+++[E9PN64_HUMAN|Unreviewed]SubName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 {ECO:0000313|Ensembl:ENSP00000432929};+++[E9PNJ9_HUMAN|Unreviewed]SubName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 {ECO:0000313|Ensembl:ENSP00000434756}; Flags: Fragment;+++[E9PPJ6_HUMAN|Unreviewed]SubName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 {ECO:0000313|Ensembl:ENSP00000432647}; Flags: Fragment;+++[E9PQZ2_HUMAN|Unreviewed]SubName: Full=CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 {ECO:0000313|Ensembl:ENSP00000432424}; Flags: Fragment;+++[Q6IBE6_HUMAN|Unreviewed]SubName: Full=SIAT4C protein {ECO:0000313|EMBL:CAG33139.1}; SubName: Full=ST3 beta-galactoside alpha-2,3-sialyltransferase 4, isoform CRA_c {ECO:0000313|EMBL:EAW67695.1}; SubName: Full=cDNA, FLJ95600, Homo sapiens sialyltransferase 4C (beta-galactosidealpha-2,3-sialyltransferase) (SIAT4C), mRNA {ECO:0000313|EMBL:BAG37279.1};"]
[64853,"'AIDA'",624,532,579,578.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005788///endoplasmic reticulum lumen","GO:0042954///lipoprotein transporter activity+++GO:0019904///protein domain specific binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0044267///cellular protein metabolic process+++GO:0043496///regulation of protein homodimerization activity+++GO:0015031///protein transport+++GO:0046329///negative regulation of JNK cascade+++GO:0007162///negative regulation of cell adhesion+++GO:1903038///negative regulation of leukocyte cell-cell adhesion+++GO:0043508///negative regulation of JUN kinase activity+++GO:2000402///negative regulation of lymphocyte migration+++GO:0042060///wound healing+++GO:0043687///post-translational protein modification+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0009953///dorsal/ventral pattern formation+++GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006887///exocytosis+++GO:0030336///negative regulation of cell migration+++GO:0002687///positive regulation of leukocyte migration+++GO:0042953///lipoprotein transport","axin interactor, dorsalization associated","[AIDA_HUMAN|Reviewed]RecName: Full=Axin interactor, dorsalization-associated protein; AltName: Full=Axin interaction partner and dorsalization antagonist;+++[B7ZW30_HUMAN|Unreviewed]SubName: Full=AIDA protein {ECO:0000313|EMBL:AAI71848.1}; Flags: Fragment;"]
[64863,"'METTL4'",61,40,39,46.6666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0009007///site-specific DNA-methyltransferase (adenine-specific) activity+++GO:0008168///methyltransferase activity","GO:0032775///DNA methylation on adenine+++GO:0032259///methylation","methyltransferase like 4","[METL4_HUMAN|Reviewed]RecName: Full=Methyltransferase-like protein 4; EC=2.1.1.-;+++[I3L0Y1_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000458415}; Flags: Fragment;+++[I3L3W2_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000460774}; Flags: Fragment;+++[I3L4A0_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000461097}; Flags: Fragment;+++[I6L9E3_HUMAN|Unreviewed]SubName: Full=METTL4 protein {ECO:0000313|EMBL:AAH56270.2}; Flags: Fragment;+++[J3KNJ7_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000320349};+++[L8EB52_HUMAN|Unreviewed]SubName: Full=Alternative protein METTL4 {ECO:0000313|EMBL:CCQ43698.1};+++[V9GYU3_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000477089}; Flags: Fragment;"]
[6494,"'SIPA1'",309,351,298,319.333333333333,"04670///Leukocyte transendothelial migration+++04015///Rap1 signaling pathway",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0030133///transport vesicle+++GO:0005634///nucleus+++GO:0012505///endomembrane system","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding","GO:0007162///negative regulation of cell adhesion+++GO:0043547///positive regulation of GTPase activity+++GO:0042631///cellular response to water deprivation+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0045786///negative regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0030308///negative regulation of cell growth+++GO:0007165///signal transduction+++GO:0007010///cytoskeleton organization+++GO:0035556///intracellular signal transduction","signal-induced proliferation-associated 1","[SIPA1_HUMAN|Reviewed]RecName: Full=Signal-induced proliferation-associated protein 1; Short=Sipa-1; AltName: Full=GTPase-activating protein Spa-1; AltName: Full=p130 SPA-1;+++[A0A024R595_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated gene 1, isoform CRA_a {ECO:0000313|EMBL:EAW74422.1};+++[E9PIB3_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated protein 1 {ECO:0000313|Ensembl:ENSP00000436683}; Flags: Fragment;+++[F6RY50_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated protein 1 {ECO:0000313|Ensembl:ENSP00000433686};"]
[64978,"'MRPL38'",819,947,916,894,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome","GO:0005515///protein binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation","mitochondrial ribosomal protein L38","[RM38_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L38, mitochondrial; Short=L38mt; Short=MRP-L38; AltName: Full=Mitochondrial large ribosomal subunit protein mL38 {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[B2R894_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein L38, isoform CRA_b {ECO:0000313|EMBL:EAW89339.1}; SubName: Full=cDNA, FLJ93795, Homo sapiens mitochondrial ribosomal protein L38 (MRPL38), nucleargene encoding mitochondrial protein, mRNA {ECO:0000313|EMBL:BAG36091.1};"]
[65008,"'MRPL1'",96,102,98,98.6666666666667,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00178///Ribosome, bacteria",null,"GO:0005840///ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005739///mitochondrion","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003735///structural constituent of ribosome","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:0000470///maturation of LSU-rRNA+++GO:0006412///translation","mitochondrial ribosomal protein L1","[RM01_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L1, mitochondrial; Short=L1mt; Short=MRP-L1; AltName: Full=Mitochondrial large ribosomal subunit protein uL1m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[A0PJ79_HUMAN|Unreviewed]SubName: Full=MRPL1 protein {ECO:0000313|EMBL:AAH17765.1}; Flags: Fragment;+++[H0Y8N7_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L1, mitochondrial {ECO:0000313|Ensembl:ENSP00000421616}; Flags: Fragment;"]
[6509,"'SLC1A4'",301,247,211,253,{"$nulls":4},"GO:0042470///melanosome+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0005813///centrosome+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0030425///dendrite+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0016021///integral component of membrane","GO:0005254///chloride channel activity+++GO:0034590///L-hydroxyproline transmembrane transporter activity+++GO:0015193///L-proline transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015194///L-serine transmembrane transporter activity+++GO:0015184///L-cystine transmembrane transporter activity+++GO:0015195///L-threonine transmembrane transporter activity+++GO:0015180///L-alanine transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015293///symporter activity","GO:0006865///amino acid transport+++GO:0015824///proline transport+++GO:0035249///synaptic transmission, glutamatergic+++GO:1902476///chloride transmembrane transport+++GO:0015808///L-alanine transport+++GO:0034589///hydroxyproline transport+++GO:0015826///threonine transport+++GO:0003333///amino acid transmembrane transport+++GO:0035524///proline transmembrane transport+++GO:0006868///glutamine transport+++GO:0015811///L-cystine transport+++GO:0050890///cognition+++GO:0055085///transmembrane transport+++GO:0015825///L-serine transport","solute carrier family 1 member 4","[SATT_HUMAN|Reviewed]RecName: Full=Neutral amino acid transporter A; AltName: Full=Alanine/serine/cysteine/threonine transporter 1; Short=ASCT-1; AltName: Full=SATT; AltName: Full=Solute carrier family 1 member 4;"]
[65123,"'INTS3'",1492.7,1468.72,1576.82,1512.74666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005730///nucleolus+++GO:0070876///SOSS complex","GO:0005515///protein binding","GO:0016180///snRNA processing+++GO:0010212///response to ionizing radiation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:0007093///mitotic cell cycle checkpoint+++GO:0042795///snRNA transcription by RNA polymerase II","integrator complex subunit 3","[INT3_HUMAN|Reviewed]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[A0A096LNW8_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000485263}; Flags: Fragment;+++[A0A096LPB9_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000485502}; Flags: Fragment;+++[H0Y8Z1_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000422616}; Flags: Fragment;"]
[65250,"'CPLANE1'",696,458,649,601,"04111///Cell cycle - yeast+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00631///Cornelia de Lange syndrome (CdLS)",null,null,"GO:0016020///membrane+++GO:0042995///cell projection+++GO:0035869///ciliary transition zone+++GO:0016021///integral component of membrane+++GO:0005929///cilium","GO:0008022///protein C-terminus binding+++GO:0047485///protein N-terminus binding+++GO:0070087///chromo shadow domain binding+++GO:0036033///mediator complex binding+++GO:0042826///histone deacetylase binding+++GO:0003682///chromatin binding","GO:0021549///cerebellum development+++GO:0001736///establishment of planar polarity+++GO:1904491///protein localization to ciliary transition zone+++GO:0007507///heart development+++GO:0003281///ventricular septum development+++GO:0030030///cell projection organization+++GO:0060021///roof of mouth development+++GO:0060271///cilium assembly+++GO:0001822///kidney development+++GO:0060976///coronary vasculature development+++GO:0003279///cardiac septum development+++GO:0042733///embryonic digit morphogenesis","ciliogenesis and planar polarity effector 1","[CPLN1_HUMAN|Reviewed]RecName: Full=Ciliogenesis and planar polarity effector 1 {ECO:0000305}; AltName: Full=Protein JBTS17;+++[H0Y9I8_HUMAN|Unreviewed]SubName: Full=Ciliogenesis and planar polarity effector 1 {ECO:0000313|Ensembl:ENSP00000424223}; Flags: Fragment;+++[H0YA77_HUMAN|Unreviewed]SubName: Full=Ciliogenesis and planar polarity effector 1 {ECO:0000313|Ensembl:ENSP00000426337}; Flags: Fragment;+++[R4GNH6_HUMAN|Unreviewed]SubName: Full=Ciliogenesis and planar polarity effector 1 {ECO:0000313|Ensembl:ENSP00000473657}; Flags: Fragment;"]
[652968,"'CASTOR1'",295,309,346,316.666666666667,"04060///Cytokine-cytokine receptor interaction+++04137///Mitophagy - animal+++04630///Jak-STAT signaling pathway+++04151///PI3K-Akt signaling pathway+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0061700///GATOR2 complex+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0034618///arginine binding","GO:1903432///regulation of TORC1 signaling+++GO:1904262///negative regulation of TORC1 signaling+++GO:1903577///cellular response to L-arginine+++GO:1902531///regulation of intracellular signal transduction","cytosolic arginine sensor for mTORC1 subunit 1","[CAST1_HUMAN|Reviewed]RecName: Full=Cytosolic arginine sensor for mTORC1 subunit 1 {ECO:0000312|HGNC:HGNC:34423}; AltName: Full=Cellular arginine sensor for mTORC1 protein 1 {ECO:0000305|PubMed:26972053}; AltName: Full=GATS-like protein 3 {ECO:0000305};+++[B7WPJ3_HUMAN|Unreviewed]SubName: Full=Cytosolic arginine sensor for mTORC1 subunit 1 {ECO:0000313|Ensembl:ENSP00000385868};+++[F2Z2C1_HUMAN|Unreviewed]SubName: Full=Cytosolic arginine sensor for mTORC1 subunit 1 {ECO:0000313|Ensembl:ENSP00000408419};+++[F2Z3I9_HUMAN|Unreviewed]SubName: Full=Cytosolic arginine sensor for mTORC1 subunit 1 {ECO:0000313|Ensembl:ENSP00000411842};+++[F8WD52_HUMAN|Unreviewed]SubName: Full=Cytosolic arginine sensor for mTORC1 subunit 1 {ECO:0000313|Ensembl:ENSP00000416041};+++[H7C2U7_HUMAN|Unreviewed]SubName: Full=Cytosolic arginine sensor for mTORC1 subunit 1 {ECO:0000313|Ensembl:ENSP00000407871}; Flags: Fragment;"]
[653464,"'SRGAP2C'",399.12,335.05,299.68,344.616666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04360///Axon guidance",{"$nulls":3},"GO:0005737///cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0048365///Rac GTPase binding+++GO:0042803///protein homodimerization activity","GO:0061000///negative regulation of dendritic spine development+++GO:2001224///positive regulation of neuron migration+++GO:0021816///extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration+++GO:0007399///nervous system development+++GO:0051490///negative regulation of filopodium assembly+++GO:0030336///negative regulation of cell migration","SLIT-ROBO Rho GTPase activating protein 2C","[SRG2C_HUMAN|Reviewed]RecName: Full=SLIT-ROBO Rho GTPase-activating protein 2C; AltName: Full=SLIT-ROBO Rho GTPase activating protein 2 pseudogene 1;+++[A0A087X0L1_HUMAN|Unreviewed]SubName: Full=SLIT-ROBO Rho GTPase-activating protein 2C {ECO:0000313|Ensembl:ENSP00000483477};"]
[653784,"'MZT2A'",522.69,589.86,504.7,539.083333333333,"01100///Metabolic pathways+++00600///Sphingolipid metabolism",null,null,"R02541///Sphingomyelin cholinephosphohydrolase Sphingomyelin + H2O <=> N-Acylsphingosine + Choline phosphate","GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0008274///gamma-tubulin ring complex+++GO:0005829///cytosol+++GO:0005819///spindle","GO:0046872///metal ion binding+++GO:0050290///sphingomyelin phosphodiesterase D activity+++GO:0004767///sphingomyelin phosphodiesterase activity","GO:0071356///cellular response to tumor necrosis factor+++GO:0046475///glycerophospholipid catabolic process+++GO:0006685///sphingomyelin catabolic process+++GO:0046513///ceramide biosynthetic process+++GO:0006687///glycosphingolipid metabolic process","mitotic spindle organizing protein 2A","[MZT2A_HUMAN|Reviewed]RecName: Full=Mitotic-spindle organizing protein 2A; AltName: Full=Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 2A;+++[H7C202_HUMAN|Unreviewed]SubName: Full=Mitotic-spindle organizing protein 2A {ECO:0000313|Ensembl:ENSP00000403353}; Flags: Fragment;"]
[654790,"'PCP4L1'",2,4,4,3.33333333333333,{"$nulls":7},"Purkinje cell protein 4 like 1","[PC4L1_HUMAN|Reviewed]RecName: Full=Purkinje cell protein 4-like protein 1; Short=PCP4-like protein 1;"]
[6566,"'SLC16A1'",2362,1822,2799,2327.66666666667,null,"H01267///Familial hyperinsulinemic hypoglycemia (HHF)+++H01248///Erythrocyte lactate transporter defect",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0005813///centrosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane","GO:0015130///mevalonate transmembrane transporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0042803///protein homodimerization activity+++GO:0097159///organic cyclic compound binding+++GO:0015129///lactate transmembrane transporter activity","GO:0032094///response to food+++GO:0006629///lipid metabolic process+++GO:0051780///behavioral response to nutrient+++GO:0035879///plasma membrane lactate transport+++GO:0050900///leukocyte migration+++GO:0055085///transmembrane transport+++GO:0015718///monocarboxylic acid transport+++GO:0007098///centrosome cycle+++GO:0035873///lactate transmembrane transport+++GO:0015728///mevalonate transport+++GO:0042593///glucose homeostasis+++GO:0006090///pyruvate metabolic process+++GO:0071407///cellular response to organic cyclic compound+++GO:0050796///regulation of insulin secretion","solute carrier family 16 member 1","[MOT1_HUMAN|Reviewed]RecName: Full=Monocarboxylate transporter 1; Short=MCT 1; AltName: Full=Solute carrier family 16 member 1;+++[A0A024R0H1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 16 (Monocarboxylic acid transporters), member 1, isoform CRA_b {ECO:0000313|EMBL:EAW56553.1};+++[B4DKS0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53381, highly similar to Monocarboxylate transporter 1 {ECO:0000313|EMBL:BAG59282.1};+++[Q5T8R3_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 1 {ECO:0000313|Ensembl:ENSP00000399104}; Flags: Fragment;+++[Q5T8R4_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 1 {ECO:0000313|Ensembl:ENSP00000397106}; Flags: Fragment;+++[Q5T8R5_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 1 {ECO:0000313|Ensembl:ENSP00000416167}; SubName: Full=Solute carrier family 16 (Monocarboxylic acid transporters), member 1, isoform CRA_a {ECO:0000313|EMBL:EAW56551.1}; Flags: Fragment;"]
[6585,"'SLIT1'",5,7,0,4,"04360///Axon guidance",{"$nulls":3},"GO:0005622///intracellular+++GO:0005615///extracellular space","GO:0005509///calcium ion binding+++GO:0048495///Roundabout binding","GO:0048846///axon extension involved in axon guidance+++GO:0022028///tangential migration from the subventricular zone to the olfactory bulb+++GO:0008045///motor neuron axon guidance+++GO:0033563///dorsal/ventral axon guidance+++GO:0007411///axon guidance+++GO:0048853///forebrain morphogenesis+++GO:0050919///negative chemotaxis+++GO:0051964///negative regulation of synapse assembly+++GO:0007097///nuclear migration+++GO:0031290///retinal ganglion cell axon guidance","slit guidance ligand 1","[SLIT1_HUMAN|Reviewed]RecName: Full=Slit homolog 1 protein; Short=Slit-1; AltName: Full=Multiple epidermal growth factor-like domains protein 4; Short=Multiple EGF-like domains protein 4; Flags: Precursor;+++[A6H8V1_HUMAN|Unreviewed]SubName: Full=Slit homolog 1 (Drosophila) {ECO:0000313|EMBL:AAI46762.1};"]
[65982,"'ZSCAN18'",1192,1231,1292,1238.33333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger and SCAN domain containing 18","[ZSC18_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 18; AltName: Full=Zinc finger protein 447;+++[A0A024R4T0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 447, isoform CRA_a {ECO:0000313|EMBL:EAW72558.1};+++[A0A0C4DG78_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000412253}; Flags: Fragment;+++[M0QXJ0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000469201}; Flags: Fragment;+++[M0QZ65_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000470329}; Flags: Fragment;+++[M0R111_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000471570};+++[M0R1U9_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000472129}; Flags: Fragment;+++[M0R364_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000473019}; Flags: Fragment;+++[M0R3C6_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000473134}; Flags: Fragment;+++[Q8WWG4_HUMAN|Unreviewed]SubName: Full=ZSCAN18 protein {ECO:0000313|EMBL:AAH17411.1}; Flags: Fragment;"]
[66002,"'CYP4F12'",1,0,2,1,{"$nulls":4},"GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016324///apical plasma membrane+++GO:0016020///membrane","GO:0005506///iron ion binding+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0046872///metal ion binding+++GO:0070330///aromatase activity+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0020037///heme binding+++GO:0004497///monooxygenase activity+++GO:0018685///alkane 1-monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0050051///leukotriene-B4 20-monooxygenase activity","GO:0000038///very long-chain fatty acid metabolic process+++GO:0003095///pressure natriuresis+++GO:0001676///long-chain fatty acid metabolic process+++GO:0003091///renal water homeostasis+++GO:0055078///sodium ion homeostasis+++GO:0017144///drug metabolic process+++GO:0036101///leukotriene B4 catabolic process+++GO:0042360///vitamin E metabolic process+++GO:0019373///epoxygenase P450 pathway+++GO:0055114///oxidation-reduction process+++GO:0019369///arachidonic acid metabolic process","cytochrome P450 family 4 subfamily F member 12","[CP4FC_HUMAN|Reviewed]RecName: Full=Cytochrome P450 4F12; EC=1.14.14.1; AltName: Full=CYPIVF12;+++[A0A024R7J9_HUMAN|Unreviewed]SubName: Full=Cytochrome P450, family 4, subfamily F, polypeptide 12, isoform CRA_b {ECO:0000313|EMBL:EAW84500.1};+++[A0A0A0MR49_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 4F12 {ECO:0000313|Ensembl:ENSP00000321821};+++[F8VR75_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 4F12 {ECO:0000313|Ensembl:ENSP00000448560};+++[F8VU50_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 4F12 {ECO:0000313|Ensembl:ENSP00000447922}; Flags: Fragment;+++[F8VZP1_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 4F12 {ECO:0000313|Ensembl:ENSP00000446812};+++[Q8IV39_HUMAN|Unreviewed]SubName: Full=Cytochrome P450, family 4, subfamily F, polypeptide 12 {ECO:0000313|EMBL:AAH35350.1};"]
[66004,"'LYNX1'",2950,3032,2831,2937.66666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0030425///dendrite+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0031225///anchored component of membrane+++GO:0016020///membrane","GO:0033130///acetylcholine receptor binding+++GO:0030550///acetylcholine receptor inhibitor activity+++GO:0008200///ion channel inhibitor activity+++GO:0030548///acetylcholine receptor regulator activity","GO:0007271///synaptic transmission, cholinergic+++GO:0099601///regulation of neurotransmitter receptor activity+++GO:2000272///negative regulation of signaling receptor activity","Ly6/neurotoxin 1","[LYNX1_HUMAN|Reviewed]RecName: Full=Ly-6/neurotoxin-like protein 1 {ECO:0000305}; AltName: Full=Endogenous prototoxin LYNX1 {ECO:0000303|PubMed:21252236}; AltName: Full=Testicular tissue protein Li 112 {ECO:0000312|EMBL:AEE61023.1}; Flags: Precursor;+++[A0A087WYG6_HUMAN|Unreviewed]SubName: Full=Ly-6/neurotoxin-like protein 1 {ECO:0000313|Ensembl:ENSP00000481790}; Flags: Fragment;+++[A0A087WZS0_HUMAN|Unreviewed]SubName: Full=Ly-6/neurotoxin-like protein 1 {ECO:0000313|Ensembl:ENSP00000482846}; Flags: Fragment;+++[L8EB58_HUMAN|Unreviewed]SubName: Full=Alternative protein LYNX1 {ECO:0000313|EMBL:CCQ43708.1};"]
[6611,"'SMS'",1856,1710,1604,1723.33333333333,"01100///Metabolic pathways+++00330///Arginine and proline metabolism+++00410///beta-Alanine metabolism+++00270///Cysteine and methionine metabolism+++00480///Glutathione metabolism","H00597///Snyder-Robinson syndrome",null,"R02869///S-adenosylmethioninamine:spermidine 3-aminopropyltransferase   S-Adenosylmethioninamine + Spermidine <=> 5'-Methylthioadenosine + Spermine","GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0016768///spermine synthase activity","GO:0006555///methionine metabolic process+++GO:0006595///polyamine metabolic process+++GO:0006597///spermine biosynthetic process","spermine synthase","[SPSY_HUMAN|Reviewed]RecName: Full=Spermine synthase; Short=SPMSY; EC=2.5.1.22; AltName: Full=Spermidine aminopropyltransferase;"]
[6627,"'SNRPA1'",154,127,142,141,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0030532///small nuclear ribonucleoprotein complex+++GO:0016604///nuclear body+++GO:0005681///spliceosomal complex+++GO:0005634///nucleus+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071013///catalytic step 2 spliceosome+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0005686///U2 snRNP+++GO:0016607///nuclear speck","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0030620///U2 snRNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0007283///spermatogenesis+++GO:0000398///mRNA splicing, via spliceosome","small nuclear ribonucleoprotein polypeptide A'","[RU2A_HUMAN|Reviewed]RecName: Full=U2 small nuclear ribonucleoprotein A'; Short=U2 snRNP A' {ECO:0000303|PubMed:2928112, ECO:0000303|PubMed:9716128};+++[H0YKK0_HUMAN|Unreviewed]SubName: Full=Small nuclear ribonucleoprotein polypeptide A', isoform CRA_a {ECO:0000313|EMBL:EAX02296.1}; SubName: Full=U2 small nuclear ribonucleoprotein A' {ECO:0000313|Ensembl:ENSP00000452836};+++[H0YLR3_HUMAN|Unreviewed]SubName: Full=U2 small nuclear ribonucleoprotein A' {ECO:0000313|Ensembl:ENSP00000453309}; Flags: Fragment;+++[H0YMA0_HUMAN|Unreviewed]SubName: Full=U2 small nuclear ribonucleoprotein A' {ECO:0000313|Ensembl:ENSP00000453521}; Flags: Fragment;+++[Q6NVW9_HUMAN|Unreviewed]SubName: Full=SNRPA1 protein {ECO:0000313|EMBL:AAH67846.1}; SubName: Full=Small nuclear ribonucleoprotein polypeptide A', isoform CRA_d {ECO:0000313|EMBL:EAX02299.1}; SubName: Full=cDNA FLJ75425, highly similar to Homo sapiens small nuclear ribonucleoprotein polypeptide A', mRNA {ECO:0000313|EMBL:BAF82767.1};"]
[6641,"'SNTB1'",242,187,274,234.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0042383///sarcolemma+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0032991///protein-containing complex+++GO:0005925///focal adhesion+++GO:0045202///synapse","GO:0030165///PDZ domain binding+++GO:0005516///calmodulin binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0003779///actin binding","GO:0006936///muscle contraction","syntrophin beta 1","[SNTB1_HUMAN|Reviewed]RecName: Full=Beta-1-syntrophin; AltName: Full=59 kDa dystrophin-associated protein A1 basic component 1; Short=DAPA1B; AltName: Full=BSYN2; AltName: Full=Syntrophin-2; AltName: Full=Tax interaction protein 43; Short=TIP-43;+++[E5RIX7_HUMAN|Unreviewed]SubName: Full=Beta-1-syntrophin {ECO:0000313|Ensembl:ENSP00000429292}; Flags: Fragment;"]
[6662,"'SOX9'",2533,1934,2674,2380.33333333333,"04024///cAMP signaling pathway","H00607///46,XY disorders of sex development (Disorders of gonadal development)+++H00598///46,XX disorders of sex development (Disorders of gonadal development)+++H00442///Campomelic dysplasia (CD)",null,null,"GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0044798///nuclear transcription factor complex","GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0046982///protein heterodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043425///bHLH transcription factor binding+++GO:0097157///pre-mRNA intronic binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0035326///enhancer binding+++GO:0003677///DNA binding+++GO:0008013///beta-catenin binding","GO:0061145///lung smooth muscle development+++GO:0060512///prostate gland morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060221///retinal rod cell differentiation+++GO:0001502///cartilage condensation+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0071773///cellular response to BMP stimulus+++GO:0072170///metanephric tubule development+++GO:0002009///morphogenesis of an epithelium+++GO:0034504///protein localization to nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0002063///chondrocyte development+++GO:0002062///chondrocyte differentiation+++GO:0043491///protein kinase B signaling+++GO:0042981///regulation of apoptotic process+++GO:0061036///positive regulation of cartilage development+++GO:0001837///epithelial to mesenchymal transition+++GO:0061046///regulation of branching involved in lung morphogenesis+++GO:0030154///cell differentiation+++GO:0032808///lacrimal gland development+++GO:0001501///skeletal system development+++GO:0035622///intrahepatic bile duct development+++GO:0070168///negative regulation of biomineral tissue development+++GO:0030903///notochord development+++GO:0048709///oligodendrocyte differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:2000794///regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0060534///trachea cartilage development+++GO:0072190///ureter urothelium development+++GO:0042127///regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010564///regulation of cell cycle process+++GO:0072189///ureter development+++GO:0006338///chromatin remodeling+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060532///bronchus cartilage development+++GO:0010628///positive regulation of gene expression+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045732///positive regulation of protein catabolic process+++GO:0019933///cAMP-mediated signaling+++GO:0003180///aortic valve morphogenesis+++GO:0030198///extracellular matrix organization+++GO:0019100///male germ-line sex determination+++GO:0014036///neural crest cell fate specification+++GO:0008584///male gonad development+++GO:0060729///intestinal epithelial structure maintenance+++GO:0001503///ossification+++GO:0030279///negative regulation of ossification+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0045595///regulation of cell differentiation+++GO:0060350///endochondral bone morphogenesis+++GO:0070371///ERK1 and ERK2 cascade+++GO:0002683///negative regulation of immune system process+++GO:0051216///cartilage development+++GO:0007010///cytoskeleton organization+++GO:0001894///tissue homeostasis+++GO:0060784///regulation of cell proliferation involved in tissue homeostasis+++GO:0060018///astrocyte fate commitment+++GO:0003188///heart valve formation+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0035019///somatic stem cell population maintenance+++GO:0030879///mammary gland development+++GO:0007219///Notch signaling pathway+++GO:0072034///renal vesicle induction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060008///Sertoli cell differentiation+++GO:0003179///heart valve morphogenesis+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:2000020///positive regulation of male gonad development+++GO:0097065///anterior head development+++GO:0060487///lung epithelial cell differentiation+++GO:0007165///signal transduction+++GO:0060041///retina development in camera-type eye+++GO:0070384///Harderian gland development+++GO:0008284///positive regulation of cell proliferation+++GO:0030916///otic vesicle formation+++GO:0072197///ureter morphogenesis+++GO:0007417///central nervous system development+++GO:0010629///negative regulation of gene expression+++GO:0006334///nucleosome assembly+++GO:2000741///positive regulation of mesenchymal stem cell differentiation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0071300///cellular response to retinoic acid+++GO:0003415///chondrocyte hypertrophy+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001942///hair follicle development+++GO:0098609///cell-cell adhesion+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1901203///positive regulation of extracellular matrix assembly+++GO:0014032///neural crest cell development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030238///male sex determination+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0072193///ureter smooth muscle cell differentiation+++GO:0031018///endocrine pancreas development+++GO:0065003///protein-containing complex assembly+++GO:0060517///epithelial cell proliferation involved in prostatic bud elongation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0007507///heart development+++GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis+++GO:0001708///cell fate specification+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0060009///Sertoli cell development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0001934///positive regulation of protein phosphorylation+++GO:0090103///cochlea morphogenesis+++GO:0045165///cell fate commitment+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0061138///morphogenesis of a branching epithelium+++GO:0090184///positive regulation of kidney development+++GO:0030155///regulation of cell adhesion+++GO:0045662///negative regulation of myoblast differentiation+++GO:2001054///negative regulation of mesenchymal cell apoptotic process+++GO:0060174///limb bud formation+++GO:0071504///cellular response to heparin+++GO:2000138///positive regulation of cell proliferation involved in heart morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030850///prostate gland development+++GO:0072289///metanephric nephron tubule formation+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0071347///cellular response to interleukin-1+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0071260///cellular response to mechanical stimulus+++GO:0030502///negative regulation of bone mineralization+++GO:0071599///otic vesicle development+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0003170///heart valve development","SRY-box 9","[SOX9_HUMAN|Reviewed]RecName: Full=Transcription factor SOX-9 {ECO:0000305};+++[A0A0U4U3E8_HUMAN|Unreviewed]SubName: Full=SRY (Sex determining region Y)-box9 {ECO:0000313|EMBL:BAS29568.1}; Flags: Fragment;+++[A0A0U4YWA5_HUMAN|Unreviewed]SubName: Full=SRY (Sex determining region Y)-box9 {ECO:0000313|EMBL:BAS29567.1}; Flags: Fragment;+++[S6CBB2_HUMAN|Unreviewed]SubName: Full=Transcription factor {ECO:0000313|EMBL:BAN66330.1}; Flags: Fragment;+++[U5XJY7_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62958.1}; Flags: Fragment;+++[U5XJZ1_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62963.1}; Flags: Fragment;+++[U5XJZ4_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62968.1}; Flags: Fragment;+++[U5XK44_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62957.1}; Flags: Fragment;+++[U5XK50_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62962.1}; Flags: Fragment;+++[U5XKW5_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62956.1}; Flags: Fragment;+++[U5XKW9_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62961.1}; Flags: Fragment;+++[U5XMM4_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62959.1}; Flags: Fragment;+++[U5XN63_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62955.1}; Flags: Fragment;+++[U5XN67_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62960.1}; Flags: Fragment;"]
[6676,"'SPAG4'",122,138,127,129,{"$nulls":4},"GO:0005929///cilium+++GO:0005634///nucleus+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005635///nuclear envelope+++GO:0031514///motile cilium+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0034993///meiotic nuclear membrane microtubule tethering complex+++GO:0005637///nuclear inner membrane","GO:0043495///protein membrane anchor+++GO:0005198///structural molecule activity+++GO:0005515///protein binding","GO:0007283///spermatogenesis+++GO:0006998///nuclear envelope organization+++GO:0030154///cell differentiation+++GO:0090286///cytoskeletal anchoring at nuclear membrane","sperm associated antigen 4","[SPAG4_HUMAN|Reviewed]RecName: Full=Sperm-associated antigen 4 protein; AltName: Full=Outer dense fiber-associated protein SPAG4; AltName: Full=SUN domain-containing protein 4;+++[C9JJZ6_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 4 protein {ECO:0000313|Ensembl:ENSP00000396670}; Flags: Fragment;+++[Q5JX49_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 4 protein {ECO:0000313|Ensembl:ENSP00000399231}; Flags: Fragment;"]
[6711,"'SPTBN1'",8106,6405,7197,7236,null,"H00231///Hereditary elliptocytosis (HE)+++H00063///Spinocerebellar ataxia (SCA)+++H01891///Autosomal recessive spinocerebellar ataxias+++H00230///Hereditary spherocytosis (SPH)",null,null,"GO:0005730///nucleolus+++GO:0005856///cytoskeleton+++GO:0030863///cortical cytoskeleton+++GO:0014731///spectrin-associated cytoskeleton+++GO:0005634///nucleus+++GO:0014069///postsynaptic density+++GO:0070062///extracellular exosome+++GO:0030673///axolemma+++GO:0098794///postsynapse+++GO:0016020///membrane+++GO:0008091///spectrin+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0032437///cuticular plate+++GO:0098978///glutamatergic synapse+++GO:0005737///cytoplasm+++GO:0031430///M band+++GO:0005886///plasma membrane","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0051020///GTPase binding+++GO:0045296///cadherin binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005543///phospholipid binding+++GO:0030506///ankyrin binding+++GO:0005516///calmodulin binding+++GO:0003779///actin binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0044877///protein-containing complex binding","GO:0071709///membrane assembly+++GO:0007009///plasma membrane organization+++GO:1900042///positive regulation of interleukin-2 secretion+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0007010///cytoskeleton organization+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043001///Golgi to plasma membrane protein transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0072659///protein localization to plasma membrane+++GO:0007182///common-partner SMAD protein phosphorylation+++GO:0007411///axon guidance+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0051693///actin filament capping+++GO:0000165///MAPK cascade+++GO:0000281///mitotic cytokinesis","spectrin beta, non-erythrocytic 1","[SPTB2_HUMAN|Reviewed]RecName: Full=Spectrin beta chain, non-erythrocytic 1; AltName: Full=Beta-II spectrin; AltName: Full=Fodrin beta chain; AltName: Full=Spectrin, non-erythroid beta chain 1;+++[A0A087WUZ3_HUMAN|Unreviewed]RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};+++[B2ZZ89_HUMAN|Unreviewed]RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};+++[B4DIF8_HUMAN|Unreviewed]SubName: Full=Spectrin, beta, non-erythrocytic 1, isoform CRA_c {ECO:0000313|EMBL:EAX00139.1}; SubName: Full=cDNA FLJ55845, highly similar to Spectrin beta chain, brain 1 {ECO:0000313|EMBL:BAG58470.1};+++[D6W5C0_HUMAN|Unreviewed]RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};+++[F8W6C1_HUMAN|Unreviewed]SubName: Full=Spectrin beta chain, non-erythrocytic 1 {ECO:0000313|Ensembl:ENSP00000374630}; Flags: Fragment;+++[K9MS24_HUMAN|Unreviewed]RecName: Full=Spectrin beta chain {ECO:0000256|PIRNR:PIRNR002297};+++[L8ECA0_HUMAN|Unreviewed]SubName: Full=Alternative protein SPTBN1 {ECO:0000313|EMBL:CCQ43202.1};+++[Q53RC4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SPTBN1 {ECO:0000313|EMBL:AAX93104.1}; Flags: Fragment;"]
[6726,"'SRP9'",1744,1506,1650,1633.33333333333,"03060///Protein export",{"$nulls":3},"GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0005785///signal recognition particle receptor complex+++GO:0005829///cytosol+++GO:0048500///signal recognition particle+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0005047///signal recognition particle binding+++GO:0008312///7S RNA binding","GO:0045900///negative regulation of translational elongation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation","signal recognition particle 9","[SRP09_HUMAN|Reviewed]RecName: Full=Signal recognition particle 9 kDa protein; Short=SRP9;+++[A0A024R3P3_HUMAN|Unreviewed]SubName: Full=Signal recognition particle 9kDa, isoform CRA_b {ECO:0000313|EMBL:EAW69752.1};+++[E9PE20_HUMAN|Unreviewed]SubName: Full=Signal recognition particle 9 kDa protein {ECO:0000313|Ensembl:ENSP00000355803};+++[Q6P2S0_HUMAN|Unreviewed]SubName: Full=SRP9 protein {ECO:0000313|EMBL:AAH64351.1};"]
[6744,"'ITPRID2'",5624,3860,4619,4701,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005102///signaling receptor binding+++GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","ITPR interacting domain containing 2","[ITPI2_HUMAN|Reviewed]RecName: Full=Protein ITPRID2 {ECO:0000305}; AltName: Full=Cleavage signal-1 protein {ECO:0000303|PubMed:1555770}; Short=CS-1 {ECO:0000303|PubMed:1555770}; AltName: Full=ITPR-interacting domain-containing protein 2 {ECO:0000305}; AltName: Full=Ki-ras-induced actin-interacting protein {ECO:0000303|PubMed:14673706}; AltName: Full=Sperm-specific antigen 2;+++[E7EUL7_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000386916};+++[E9PHV5_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000387319};+++[F2Z295_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000392049};+++[H7BZ26_HUMAN|Unreviewed]SubName: Full=ITPR-interacting domain-containing 2 {ECO:0000313|Ensembl:ENSP00000387420}; Flags: Fragment;"]
[6776,"'STAT5A'",176.84,202.97,178.02,185.943333333333,"04012///ErbB signaling pathway+++05200///Pathways in cancer+++05166///HTLV-I infection+++04917///Prolactin signaling pathway+++04659///Th17 cell differentiation+++05221///Acute myeloid leukemia+++04933///AGE-RAGE signaling pathway in diabetic complications+++05162///Measles+++05203///Viral carcinogenesis+++04217///Necroptosis+++05161///Hepatitis B+++05223///Non-small cell lung cancer+++04658///Th1 and Th2 cell differentiation+++04630///Jak-STAT signaling pathway+++05220///Chronic myeloid leukemia","H00931///Growth hormone insensitivity with immunodeficiency","M00684///JAK-STAT signaling",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0004713///protein tyrosine kinase activity+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0007259///JAK-STAT cascade+++GO:0019530///taurine metabolic process+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0040014///regulation of multicellular organism growth+++GO:0038113///interleukin-9-mediated signaling pathway+++GO:0007595///lactation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007165///signal transduction+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0038110///interleukin-2-mediated signaling pathway+++GO:0043536///positive regulation of blood vessel endothelial cell migration","signal transducer and activator of transcription 5A","[STA5A_HUMAN|Reviewed]RecName: Full=Signal transducer and activator of transcription 5A;+++[A8K6I5_HUMAN|Unreviewed]RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};+++[C9JVV6_HUMAN|Unreviewed]SubName: Full=Signal transducer and activator of transcription 5A {ECO:0000313|Ensembl:ENSP00000407327}; Flags: Fragment;+++[K7EIF9_HUMAN|Unreviewed]SubName: Full=Signal transducer and activator of transcription 5A {ECO:0000313|Ensembl:ENSP00000464730}; Flags: Fragment;+++[K7EK35_HUMAN|Unreviewed]RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};+++[K7EM17_HUMAN|Unreviewed]SubName: Full=Signal transducer and activator of transcription 5A {ECO:0000313|Ensembl:ENSP00000466320};+++[Q59GY7_HUMAN|Unreviewed]RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415}; Flags: Fragment;+++[Q8WWS9_HUMAN|Unreviewed]RecName: Full=Signal transducer and activator of transcription {ECO:0000256|RuleBase:RU046415};"]
[6786,"'STIM1'",1498,1469,1897,1621.33333333333,"04611///Platelet activation+++04020///Calcium signaling pathway","H00093///Combined immunodeficiencies (CIDs)",null,null,"GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0005887///integral component of plasma membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0044853///plasma membrane raft+++GO:0032541///cortical endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0030426///growth cone+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005874///microtubule+++GO:0032991///protein-containing complex+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016529///sarcoplasmic reticulum","GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0015279///store-operated calcium channel activity+++GO:0051010///microtubule plus-end binding+++GO:0005509///calcium ion binding+++GO:0005246///calcium channel regulator activity+++GO:0002020///protease binding+++GO:0005515///protein binding","GO:0070588///calcium ion transmembrane transport+++GO:0002115///store-operated calcium entry+++GO:0051924///regulation of calcium ion transport+++GO:0006811///ion transport+++GO:0006874///cellular calcium ion homeostasis+++GO:0045762///positive regulation of adenylate cyclase activity+++GO:2001256///regulation of store-operated calcium entry+++GO:0070166///enamel mineralization+++GO:0045766///positive regulation of angiogenesis+++GO:0005513///detection of calcium ion+++GO:1903779///regulation of cardiac conduction+++GO:0032237///activation of store-operated calcium channel activity+++GO:0006816///calcium ion transport+++GO:0006812///cation transport+++GO:0014902///myotube differentiation","stromal interaction molecule 1","[STIM1_HUMAN|Reviewed]RecName: Full=Stromal interaction molecule 1; Flags: Precursor;+++[E9PIQ8_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000433949}; Flags: Fragment;+++[E9PJ19_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000431878}; Flags: Fragment;+++[E9PMB4_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000431191}; Flags: Fragment;+++[E9PN27_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000434848}; Flags: Fragment;+++[E9PNJ4_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000434767};+++[E9PR07_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000432383}; Flags: Fragment;+++[E9PR09_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000432378}; Flags: Fragment;+++[E9PRE4_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000434200}; Flags: Fragment;+++[E9PRZ7_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000432210}; Flags: Fragment;+++[G0XQ39_HUMAN|Unreviewed]SubName: Full=STIM1L {ECO:0000313|EMBL:ADO20317.1}; SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000478059};+++[H0YDB2_HUMAN|Unreviewed]SubName: Full=Stromal interaction molecule 1 {ECO:0000313|Ensembl:ENSP00000433266}; Flags: Fragment;+++[V5J3L2_HUMAN|Unreviewed]SubName: Full=STIM1 {ECO:0000313|EMBL:AFZ76986.1};"]
[6820,"'SULT2B1'",1,0,1,0.666666666666667,"00140///Steroid hormone biosynthesis","H00734///Autosomal recessive congenital ichthyosis",null,"R03405///3'-phosphoadenylylsulfate:alcohol sulfotransferase   3'-Phosphoadenylyl sulfate + Dehydroepiandrosterone <=> Adenosine 3',5'-bisphosphate + Dehydroepiandrosterone sulfate+++R08977///3'-phosphoadenylyl-sulfate:cholesterol sulfotransferase   Cholesterol + 3'-Phosphoadenylyl sulfate <=> Cholesterol sulfate + Adenosine 3',5'-bisphosphate+++R00629///3'-phosphoadenylyl-sulfate:alcohol sulfotransferase   Alcohol + 3'-Phosphoadenylyl sulfate <=> Alkyl sulfate + Adenosine 3',5'-bisphosphate+++R08978///3'-phosphoadenylyl-sulfate:pregnenolone sulfotransferase   Pregnenolone + 3'-Phosphoadenylyl sulfate <=> 3beta-Hydroxypregn-5-en-20-one sulfate + Adenosine 3',5'-bisphosphate","GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:1990239///steroid hormone binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0015485///cholesterol binding+++GO:0004027///alcohol sulfotransferase activity+++GO:0050294///steroid sulfotransferase activity+++GO:0005515///protein binding+++GO:0008146///sulfotransferase activity","GO:0008203///cholesterol metabolic process+++GO:0006629///lipid metabolic process+++GO:0000103///sulfate assimilation+++GO:0008285///negative regulation of cell proliferation+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0045606///positive regulation of epidermal cell differentiation+++GO:0008202///steroid metabolic process","sulfotransferase family 2B member 1","[ST2B1_HUMAN|Reviewed]RecName: Full=Sulfotransferase family cytosolic 2B member 1; Short=ST2B1; Short=Sulfotransferase 2B1; EC=2.8.2.2; AltName: Full=Alcohol sulfotransferase; AltName: Full=Hydroxysteroid sulfotransferase 2;"]
[6835,"'SURF2'",177,223,172,190.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0005886///plasma membrane","GO:0003674///molecular_function","GO:0008150///biological_process","surfeit 2","[SURF2_HUMAN|Reviewed]RecName: Full=Surfeit locus protein 2; Short=Surf-2;+++[A0A024R8G1_HUMAN|Unreviewed]SubName: Full=Surfeit 2, isoform CRA_a {ECO:0000313|EMBL:EAW88069.1};"]
[6868,"'ADAM17'",555,477,481,504.333333333333,"05010///Alzheimer's disease+++04330///Notch signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection",null,"M00682///Notch signaling",null,"GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016324///apical plasma membrane+++GO:0032587///ruffle membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0015629///actin cytoskeleton+++GO:0045121///membrane raft","GO:0017124///SH3 domain binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0005138///interleukin-6 receptor binding+++GO:0004175///endopeptidase activity+++GO:0046872///metal ion binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0030165///PDZ domain binding+++GO:0005112///Notch binding+++GO:0005178///integrin binding+++GO:0008237///metallopeptidase activity","GO:0002446///neutrophil mediated immunity+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0071403///cellular response to high density lipoprotein particle stimulus+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0007155///cell adhesion+++GO:0032496///response to lipopolysaccharide+++GO:0033025///regulation of mast cell apoptotic process+++GO:0051088///PMA-inducible membrane protein ectodomain proteolysis+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0045741///positive regulation of epidermal growth factor-activated receptor activity+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0006508///proteolysis+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0033627///cell adhesion mediated by integrin+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0030335///positive regulation of cell migration+++GO:0030307///positive regulation of cell growth+++GO:0042493///response to drug+++GO:0030183///B cell differentiation+++GO:0048870///cell motility+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0035624///receptor transactivation+++GO:0030154///cell differentiation+++GO:0032722///positive regulation of chemokine production+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0008284///positive regulation of cell proliferation+++GO:0007283///spermatogenesis+++GO:0007220///Notch receptor processing+++GO:0051272///positive regulation of cellular component movement+++GO:0002467///germinal center formation+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0048536///spleen development+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0033077///T cell differentiation in thymus","ADAM metallopeptidase domain 17","[ADA17_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 17; Short=ADAM 17; EC=3.4.24.86 {ECO:0000269|PubMed:12441351, ECO:0000269|PubMed:20592283, ECO:0000269|PubMed:24227843}; AltName: Full=Snake venom-like protease; AltName: Full=TNF-alpha convertase; AltName: Full=TNF-alpha-converting enzyme; AltName: CD_antigen=CD156b; Flags: Precursor;+++[A6H8L4_HUMAN|Unreviewed]SubName: Full=ADAM17 protein {ECO:0000313|EMBL:AAI46659.1}; SubName: Full=Disintegrin and metalloproteinase domain-containing protein 17 {ECO:0000313|Ensembl:ENSP00000480552};+++[B2RNB2_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase domain 17 {ECO:0000313|EMBL:AAI36784.1}; SubName: Full=ADAM metallopeptidase domain 17 (Tumor necrosis factor, alpha, converting enzyme), isoform CRA_b {ECO:0000313|EMBL:EAX00982.1}; SubName: Full=ADAM metallopeptidase domain 18 {ECO:0000313|EMBL:ACV30013.1};+++[E7EUI5_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 17 {ECO:0000313|Ensembl:ENSP00000418728};+++[Q53RF5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ADAM17 {ECO:0000313|EMBL:AAX93091.1}; Flags: Fragment;+++[Q53RS1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ADAM17 {ECO:0000313|EMBL:AAY14859.1}; Flags: Fragment;+++[Q53S40_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ADAM17 {ECO:0000313|EMBL:AAX93142.1}; Flags: Fragment;+++[Q6P5T8_HUMAN|Unreviewed]SubName: Full=ADAM17 protein {ECO:0000313|EMBL:AAH62687.1};"]
[6877,"'TAF5'",29,13,23,21.6666666666667,"05168///Herpes simplex infection+++03022///Basal transcription factors",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0033276///transcription factor TFTC complex+++GO:0005669///transcription factor TFIID complex+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0015629///actin cytoskeleton+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity+++GO:0004402///histone acetyltransferase activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0044212///transcription regulatory region DNA binding","GO:0016573///histone acetylation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0016032///viral process+++GO:0006325///chromatin organization+++GO:0006352///DNA-templated transcription, initiation","TATA-box binding protein associated factor 5","[TAF5_HUMAN|Reviewed]RecName: Full=Transcription initiation factor TFIID subunit 5; AltName: Full=Transcription initiation factor TFIID 100 kDa subunit; Short=TAF(II)100; Short=TAFII-100; Short=TAFII100;"]
[6905,"'TBCE'",232,252,270,251.333333333333,null,"H00622///Hypoparathyroidism-retardation-dysmorphism syndrome+++H00619///Kenny-Caffey syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005840///ribosome+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0051087///chaperone binding+++GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0007052///mitotic spindle organization+++GO:0006457///protein folding+++GO:0008299///isoprenoid biosynthetic process+++GO:0000226///microtubule cytoskeleton organization+++GO:0007023///post-chaperonin tubulin folding pathway","tubulin folding cofactor E","[TBCE_HUMAN|Reviewed]RecName: Full=Tubulin-specific chaperone E; AltName: Full=Tubulin-folding cofactor E;+++[A0A2R8Y3S1_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000493539}; Flags: Fragment;+++[A0A2R8Y4E7_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000493737}; Flags: Fragment;+++[A0A2R8Y4N4_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494196};+++[A0A2R8Y4P2_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494208};+++[A0A2R8Y4V6_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494102};+++[A0A2R8Y551_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494203}; Flags: Fragment;+++[A0A2R8Y597_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494291};+++[A0A2R8Y5H6_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494541};+++[A0A2R8Y5Q8_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494646};+++[A0A2R8Y6G3_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495295}; Flags: Fragment;+++[A0A2R8Y6L2_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495319}; Flags: Fragment;+++[A0A2R8Y6Q1_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495693}; SubName: Full=Tubulin-specific chaperone e, isoform CRA_b {ECO:0000313|EMBL:EAW70022.1};+++[A0A2R8Y720_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495738}; Flags: Fragment;+++[A0A2R8Y784_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495916};+++[A0A2R8Y787_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495928};+++[A0A2R8Y7E7_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495953};+++[A0A2R8Y7H8_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496033}; Flags: Fragment;+++[A0A2R8Y7P7_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496173};+++[A0A2R8Y809_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496380};+++[A0A2R8Y897_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496612}; Flags: Fragment;+++[A0A2R8YE82_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495370};+++[A0A2R8YER9_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495831};+++[A0A2R8YF12_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496048}; Flags: Fragment;+++[A0A2R8YFG9_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495125}; Flags: Fragment;+++[A0A2R8YFL4_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495225}; Flags: Fragment;+++[A0A2R8YFM3_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495257};+++[A0A2R8YH53_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496495};+++[A0A2R8YHI9_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496773};+++[A0A2U3TZJ6_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000355560}; SubName: Full=Tubulin-specific chaperone e, isoform CRA_c {ECO:0000313|EMBL:EAW70023.1};"]
[6915,"'TBXA2R'",29.17,24,29.19,27.4533333333333,"04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04611///Platelet activation","H01235///Bleeding disorder platelet-type",null,null,"GO:0005887///integral component of plasma membrane+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004961///thromboxane A2 receptor activity+++GO:0004960///thromboxane receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007584///response to nutrient+++GO:0045907///positive regulation of vasoconstriction+++GO:0019229///regulation of vasoconstriction+++GO:0038193///thromboxane A2 signaling pathway+++GO:0045471///response to ethanol+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0019932///second-messenger-mediated signaling+++GO:0030194///positive regulation of blood coagulation+++GO:0007165///signal transduction+++GO:0032496///response to lipopolysaccharide+++GO:0033574///response to testosterone+++GO:0006954///inflammatory response+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0045766///positive regulation of angiogenesis+++GO:0045777///positive regulation of blood pressure+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0042493///response to drug+++GO:0071222///cellular response to lipopolysaccharide","thromboxane A2 receptor","[TA2R_HUMAN|Reviewed]RecName: Full=Thromboxane A2 receptor; Short=TXA2-R; AltName: Full=Prostanoid TP receptor;+++[K7ER80_HUMAN|Unreviewed]SubName: Full=Thromboxane A2 receptor {ECO:0000313|Ensembl:ENSP00000468145};+++[Q05C92_HUMAN|Unreviewed]SubName: Full=TBXA2R protein {ECO:0000313|EMBL:AAH28027.1}; Flags: Fragment;+++[Q0VAA9_HUMAN|Unreviewed]SubName: Full=TBXA2R protein {ECO:0000313|EMBL:AAI21150.1};+++[Q0VAB0_HUMAN|Unreviewed]SubName: Full=TBXA2R protein {ECO:0000313|EMBL:AAI21149.1};"]
[6926,"'TBX3'",42,22,22,28.6666666666667,"04550///Signaling pathways regulating pluripotency of stem cells","H00637///Ulnar-mammary syndrome",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0035136///forelimb morphogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0060923///cardiac muscle cell fate commitment+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0055007///cardiac muscle cell differentiation+++GO:0060931///sinoatrial node cell development+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0030540///female genitalia development+++GO:0035050///embryonic heart tube development+++GO:0032275///luteinizing hormone secretion+++GO:0007569///cell aging+++GO:0060412///ventricular septum morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035108///limb morphogenesis+++GO:0001501///skeletal system development+++GO:0035115///embryonic forelimb morphogenesis+++GO:0001947///heart looping+++GO:0030539///male genitalia development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042127///regulation of cell proliferation+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0003167///atrioventricular bundle cell differentiation+++GO:0003007///heart morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0001701///in utero embryonic development+++GO:0030879///mammary gland development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0046884///follicle-stimulating hormone secretion+++GO:0009887///animal organ morphogenesis+++GO:2000648///positive regulation of stem cell proliferation+++GO:0090398///cellular senescence+++GO:0006355///regulation of transcription, DNA-templated+++GO:0019827///stem cell population maintenance+++GO:0045787///positive regulation of cell cycle+++GO:0060596///mammary placode formation+++GO:0003151///outflow tract morphogenesis+++GO:0060021///roof of mouth development+++GO:0048332///mesoderm morphogenesis+++GO:0045662///negative regulation of myoblast differentiation+++GO:0010159///specification of animal organ position+++GO:0001568///blood vessel development+++GO:0007275///multicellular organism development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021761///limbic system development","T-box 3","[TBX3_HUMAN|Reviewed]RecName: Full=T-box transcription factor TBX3; Short=T-box protein 3;+++[A0A024RBL6_HUMAN|Unreviewed]SubName: Full=T-box 3 (Ulnar mammary syndrome), isoform CRA_c {ECO:0000313|EMBL:EAW98073.1};+++[A0A024RBQ4_HUMAN|Unreviewed]SubName: Full=T-box 3 (Ulnar mammary syndrome), isoform CRA_a {ECO:0000313|EMBL:EAW98074.1};"]
[6988,"'TCTA'",942.02,1105.08,1106,1051.03333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005622///intracellular+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0045671///negative regulation of osteoclast differentiation+++GO:0072675///osteoclast fusion","T cell leukemia translocation altered","[TCTA_HUMAN|Reviewed]RecName: Full=T-cell leukemia translocation-altered gene protein; AltName: Full=T-cell leukemia translocation-associated gene protein;+++[A0A024R2X9_HUMAN|Unreviewed]SubName: Full=T-cell leukemia translocation altered gene, isoform CRA_a {ECO:0000313|EMBL:EAW64983.1};"]
[7005,"'TEAD3'",1091,1300,1078,1156.33333333333,"04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species+++04011///MAPK signaling pathway - yeast+++04391///Hippo signaling pathway - fly","H01180///Sveinsson chorioretinal atrophy (SCRA)","M00683///Hippo signaling",null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007565///female pregnancy+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035329///hippo signaling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0055059///asymmetric neuroblast division","TEA domain transcription factor 3","[TEAD3_HUMAN|Reviewed]RecName: Full=Transcriptional enhancer factor TEF-5; AltName: Full=DTEF-1; AltName: Full=TEA domain family member 3; Short=TEAD-3;+++[A0A1X7SBS4_HUMAN|Unreviewed]RecName: Full=Transcriptional enhancer factor TEF-5 {ECO:0000256|PIRNR:PIRNR002603};+++[B5MCM0_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-5 {ECO:0000313|Ensembl:ENSP00000384577};+++[H7C4A7_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-5 {ECO:0000313|Ensembl:ENSP00000416400}; Flags: Fragment;+++[Q96G15_HUMAN|Unreviewed]SubName: Full=TEAD3 protein {ECO:0000313|EMBL:AAH10053.2}; Flags: Fragment;"]
[7029,"'TFDP2'",1079.87,983.25,1070.55,1044.55666666667,"04110///Cell cycle",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005667///transcription factor complex+++GO:0005739///mitochondrion","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0003712///transcription coregulator activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:1903506///regulation of nucleic acid-templated transcription+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0000278///mitotic cell cycle+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007507///heart development","transcription factor Dp-2","[TFDP2_HUMAN|Reviewed]RecName: Full=Transcription factor Dp-2; AltName: Full=E2F dimerization partner 2;+++[C9J461_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417220}; Flags: Fragment;+++[C9J5D5_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417108}; Flags: Fragment;+++[C9J872_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417726}; Flags: Fragment;+++[C9J977_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000418122}; Flags: Fragment;+++[C9JCY5_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000420657}; Flags: Fragment;+++[C9JNB6_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000420456}; Flags: Fragment;+++[C9JTZ9_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000419540}; Flags: Fragment;+++[F8WAY9_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417384};+++[H7C5C2_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000419507}; Flags: Fragment;+++[R4GN09_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000473436}; Flags: Fragment;"]
[7046,"'TGFBR1'",245,200,212,219,"04144///Endocytosis+++04390///Hippo signaling pathway+++04371///Apelin signaling pathway+++05212///Pancreatic cancer+++05225///Hepatocellular carcinoma+++05210///Colorectal cancer+++04380///Osteoclast differentiation+++04659///Th17 cell differentiation+++05200///Pathways in cancer+++04060///Cytokine-cytokine receptor interaction+++04520///Adherens junction+++04218///Cellular senescence+++05220///Chronic myeloid leukemia+++04350///TGF-beta signaling pathway+++05161///Hepatitis B+++05142///Chagas disease (American trypanosomiasis)+++05166///HTLV-I infection+++04926///Relaxin signaling pathway+++05226///Gastric cancer+++04068///FoxO signaling pathway+++04010///MAPK signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications","H00018///Gastric cancer+++H00800///Loeys-Dietz syndrome (LDS)+++H00801///Familial thoracic aortic aneurysm and dissection (TAAD)","M00680///TGF-beta signaling",null,"GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0030054///cell junction+++GO:0005623///cell+++GO:0016020///membrane+++GO:0005923///bicellular tight junction+++GO:0005768///endosome+++GO:0048179///activin receptor complex","GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005025///transforming growth factor beta receptor activity, type I+++GO:0005102///signaling receptor binding+++GO:0000166///nucleotide binding+++GO:0046332///SMAD binding+++GO:0048185///activin binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0050431///transforming growth factor beta binding+++GO:0046872///metal ion binding+++GO:0070411///I-SMAD binding+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0019838///growth factor binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity","GO:0060317///cardiac epithelial to mesenchymal transition+++GO:1905223///epicardium morphogenesis+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0030154///cell differentiation+++GO:0001525///angiogenesis+++GO:0048538///thymus development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043065///positive regulation of apoptotic process+++GO:0009952///anterior/posterior pattern specification+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0001701///in utero embryonic development+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0060017///parathyroid gland development+++GO:0031396///regulation of protein ubiquitination+++GO:0001822///kidney development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048663///neuron fate commitment+++GO:0030335///positive regulation of cell migration+++GO:0048705///skeletal system morphogenesis+++GO:0007389///pattern specification process+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:1905075///positive regulation of tight junction disassembly+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0009791///post-embryonic development+++GO:0048870///cell motility+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0060982///coronary artery morphogenesis+++GO:0060978///angiogenesis involved in coronary vascular morphogenesis+++GO:0016310///phosphorylation+++GO:0030307///positive regulation of cell growth+++GO:0003342///proepicardium development+++GO:0042118///endothelial cell activation+++GO:0030199///collagen fibril organization+++GO:0002088///lens development in camera-type eye+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0040008///regulation of growth+++GO:0007050///cell cycle arrest+++GO:0008354///germ cell migration+++GO:0007507///heart development+++GO:0043393///regulation of protein binding+++GO:0016579///protein deubiquitination+++GO:1905007///positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0060021///roof of mouth development+++GO:0060412///ventricular septum morphogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0001824///blastocyst development+++GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0060043///regulation of cardiac muscle cell proliferation+++GO:0032924///activin receptor signaling pathway+++GO:0048762///mesenchymal cell differentiation+++GO:0001837///epithelial to mesenchymal transition+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0048844///artery morphogenesis+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0051272///positive regulation of cellular component movement+++GO:0006915///apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0008584///male gonad development+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0000186///activation of MAPKK activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0042060///wound healing+++GO:0010468///regulation of gene expression+++GO:0035556///intracellular signal transduction+++GO:0001501///skeletal system development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0070723///response to cholesterol+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0043062///extracellular structure organization+++GO:0060037///pharyngeal system development+++GO:0051491///positive regulation of filopodium assembly+++GO:0018105///peptidyl-serine phosphorylation+++GO:0010628///positive regulation of gene expression+++GO:0051496///positive regulation of stress fiber assembly+++GO:0043542///endothelial cell migration","transforming growth factor beta receptor 1","[TGFR1_HUMAN|Reviewed]RecName: Full=TGF-beta receptor type-1; Short=TGFR-1; EC=2.7.11.30; AltName: Full=Activin A receptor type II-like protein kinase of 53kD; AltName: Full=Activin receptor-like kinase 5; Short=ALK-5; Short=ALK5; AltName: Full=Serine/threonine-protein kinase receptor R4; Short=SKR4; AltName: Full=TGF-beta type I receptor; AltName: Full=Transforming growth factor-beta receptor type I; Short=TGF-beta receptor type I; Short=TbetaR-I; Flags: Precursor;+++[A6MIV6_HUMAN|Unreviewed]SubName: Full=Mutant transforming growth factor beta receptor I {ECO:0000313|EMBL:ABO93068.1}; Flags: Fragment;+++[A6MIV7_HUMAN|Unreviewed]SubName: Full=Mutant transforming growth factor beta receptor I {ECO:0000313|EMBL:ABO93069.1}; Flags: Fragment;+++[B4DXN7_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109};+++[B4DY26_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109};+++[F8VRH6_HUMAN|Unreviewed]SubName: Full=TGF-beta receptor type-1 {ECO:0000313|Ensembl:ENSP00000448518}; Flags: Fragment;+++[F8VVC4_HUMAN|Unreviewed]SubName: Full=TGF-beta receptor type-1 {ECO:0000313|Ensembl:ENSP00000449934}; Flags: Fragment;+++[F8VXZ5_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109}; Flags: Fragment;+++[F8W0K6_HUMAN|Unreviewed]SubName: Full=TGF-beta receptor type-1 {ECO:0000313|Ensembl:ENSP00000447182}; Flags: Fragment;+++[F8W1R9_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109};+++[H0YHS4_HUMAN|Unreviewed]SubName: Full=TGF-beta receptor type-1 {ECO:0000313|Ensembl:ENSP00000447707}; Flags: Fragment;+++[Q5T7S2_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109};"]
[7067,"'THRA'",664,623,720,669,"04080///Neuroactive ligand-receptor interaction+++04919///Thyroid hormone signaling pathway","H00250///Congenital nongoitrous hypothyroidism (CHNG)",null,null,"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0044877///protein-containing complex binding+++GO:0003707///steroid hormone receptor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0038023///signaling receptor activity+++GO:0070324///thyroid hormone binding+++GO:0004879///nuclear receptor activity+++GO:0031490///chromatin DNA binding+++GO:0017025///TBP-class protein binding+++GO:0004887///thyroid hormone receptor activity+++GO:0008134///transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0019904///protein domain specific binding","GO:0030218///erythrocyte differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2000143///negative regulation of DNA-templated transcription, initiation+++GO:0033993///response to lipid+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0009887///animal organ morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0009409///response to cold+++GO:0030878///thyroid gland development+++GO:0033032///regulation of myeloid cell apoptotic process+++GO:0050994///regulation of lipid catabolic process+++GO:0060509///type I pneumocyte differentiation+++GO:0009755///hormone-mediated signaling pathway+++GO:0030522///intracellular receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0001502///cartilage condensation+++GO:0008016///regulation of heart contraction+++GO:0045925///positive regulation of female receptivity+++GO:0008050///female courtship behavior+++GO:0007611///learning or memory+++GO:0030154///cell differentiation+++GO:0017055///negative regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007420///brain development+++GO:0002155///regulation of thyroid hormone mediated signaling pathway+++GO:0001503///ossification","thyroid hormone receptor alpha","[THA_HUMAN|Reviewed]RecName: Full=Thyroid hormone receptor alpha; AltName: Full=Nuclear receptor subfamily 1 group A member 1; AltName: Full=V-erbA-related protein 7; Short=EAR-7; AltName: Full=c-erbA-1; AltName: Full=c-erbA-alpha;+++[A0A0R5RI31_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha 1 {ECO:0000313|EMBL:AIW04492.1}; Flags: Fragment;+++[A0A0R5RI36_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha 1 {ECO:0000313|EMBL:AIW04479.1}; Flags: Fragment;+++[A0A0R5RI44_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha 1 {ECO:0000313|EMBL:AIW04480.1}; Flags: Fragment;+++[A0A0R5RI47_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha 1 {ECO:0000313|EMBL:AIW04482.1}; Flags: Fragment;+++[A0A0R5RI63_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha 1 {ECO:0000313|EMBL:AIW04481.1}; Flags: Fragment;+++[B6ZGR6_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha {ECO:0000313|EMBL:BAH02277.1};+++[J3KTF3_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha {ECO:0000313|Ensembl:ENSP00000462955}; Flags: Fragment;+++[J3QR26_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha {ECO:0000313|Ensembl:ENSP00000464013}; Flags: Fragment;+++[J3QRA9_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha {ECO:0000313|Ensembl:ENSP00000464123}; Flags: Fragment;+++[J3QRW5_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor alpha {ECO:0000313|Ensembl:ENSP00000464414}; Flags: Fragment;+++[Q6FH41_HUMAN|Unreviewed]SubName: Full=THRA protein {ECO:0000313|EMBL:CAG46713.1}; SubName: Full=Thyroid hormone receptor, alpha (Erythroblastic leukemia viral (V-erb-a) oncogene homolog, avian), isoform CRA_b {ECO:0000313|EMBL:EAW60633.1}; SubName: Full=Thyroid normone nuclear receptor alpha variant 1 {ECO:0000313|EMBL:ADZ17370.1}; Flags: Fragment;"]
[7082,"'TJP1'",2817,1971,2236,2341.33333333333,"05132///Salmonella infection+++04530///Tight junction+++04520///Adherens junction+++04540///Gap junction+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05110///Vibrio cholerae infection",{"$nulls":3},"GO:0043296///apical junction complex+++GO:0016324///apical plasma membrane+++GO:0016327///apicolateral plasma membrane+++GO:0002102///podosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0045177///apical part of cell+++GO:0030054///cell junction+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0046581///intercellular canaliculus+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0005923///bicellular tight junction+++GO:0016323///basolateral plasma membrane+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0070160///tight junction+++GO:0005912///adherens junction+++GO:0014704///intercalated disc+++GO:0005921///gap junction","GO:0045296///cadherin binding+++GO:0008022///protein C-terminus binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0071253///connexin binding","GO:0043116///negative regulation of vascular permeability+++GO:0007043///cell-cell junction assembly+++GO:0071000///response to magnetism+++GO:0042493///response to drug+++GO:0001825///blastocyst formation+++GO:0007605///sensory perception of sound+++GO:0045471///response to ethanol+++GO:0090557///establishment of endothelial intestinal barrier+++GO:2000810///regulation of bicellular tight junction assembly+++GO:0032496///response to lipopolysaccharide+++GO:0035329///hippo signaling+++GO:1901350///cell-cell signaling involved in cell-cell junction organization+++GO:0071333///cellular response to glucose stimulus","tight junction protein 1","[ZO1_HUMAN|Reviewed]RecName: Full=Tight junction protein ZO-1; AltName: Full=Tight junction protein 1; AltName: Full=Zona occludens protein 1; AltName: Full=Zonula occludens protein 1;+++[A0A087X0K9_HUMAN|Unreviewed]SubName: Full=Tight junction protein ZO-1 {ECO:0000313|Ensembl:ENSP00000483470};+++[A9CQZ8_HUMAN|Unreviewed]SubName: Full=Tight junction protein ZO-1 {ECO:0000313|EMBL:BAF95000.1}; Flags: Fragment;+++[B4DZK4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50931, highly similar to Tight junction protein ZO-1 {ECO:0000313|EMBL:BAG64116.1};+++[G3V1L9_HUMAN|Unreviewed]SubName: Full=Tight junction protein 1 (Zona occludens 1), isoform CRA_a {ECO:0000313|EMBL:EAW51506.1}; SubName: Full=Tight junction protein ZO-1 {ECO:0000313|Ensembl:ENSP00000348416};+++[G5E9E7_HUMAN|Unreviewed]SubName: Full=Tight junction protein 1 (Zona occludens 1), isoform CRA_e {ECO:0000313|EMBL:EAW51510.1}; SubName: Full=Tight junction protein ZO-1 {ECO:0000313|Ensembl:ENSP00000382890};+++[H0Y3R8_HUMAN|Unreviewed]SubName: Full=Tight junction protein ZO-1 {ECO:0000313|Ensembl:ENSP00000382887}; Flags: Fragment;+++[H0YKB1_HUMAN|Unreviewed]SubName: Full=Tight junction protein 1 (Zona occludens 1), isoform CRA_d {ECO:0000313|EMBL:EAW51509.1}; SubName: Full=Tight junction protein ZO-1 {ECO:0000313|Ensembl:ENSP00000452729};+++[H0YLT6_HUMAN|Unreviewed]SubName: Full=Tight junction protein ZO-1 {ECO:0000313|Ensembl:ENSP00000453334}; Flags: Fragment;+++[L0R559_HUMAN|Unreviewed]SubName: Full=Alternative protein TJP1 {ECO:0000313|EMBL:CCO13833.1};+++[Q6MZU1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686A1195 {ECO:0000313|EMBL:CAE45936.1};+++[Q9H317_HUMAN|Unreviewed]SubName: Full=Tight junction protein ZO-1 {ECO:0000313|EMBL:AAG43399.1}; Flags: Fragment;"]
[71,"'ACTG1'",105006.01,106436,99093,103511.67,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04919///Thyroid hormone signaling pathway+++04015///Rap1 signaling pathway+++05416///Viral myocarditis+++04670///Leukocyte transendothelial migration+++04145///Phagosome+++04520///Adherens junction+++05131///Shigellosis+++05418///Fluid shear stress and atherosclerosis+++04390///Hippo signaling pathway+++05410///Hypertrophic cardiomyopathy (HCM)+++05225///Hepatocellular carcinoma+++04210///Apoptosis+++04611///Platelet activation+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++04714///Thermogenesis+++05110///Vibrio cholerae infection+++05414///Dilated cardiomyopathy (DCM)+++04921///Oxytocin signaling pathway+++05205///Proteoglycans in cancer+++04510///Focal adhesion+++04530///Tight junction+++04745///Phototransduction - fly+++05130///Pathogenic Escherichia coli infection+++04391///Hippo signaling pathway - fly+++04810///Regulation of actin cytoskeleton+++05164///Influenza A","H02023///Baraitser-Winter syndrome+++H00604///Deafness, autosomal dominant+++H01705///Bilateral sudden sensorineural hearing loss+++H00101///Other phagocyte defects+++H01255///Juvenile-onset dystonia",null,null,"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0031941///filamentous actin+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0030016///myofibril+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0044305///calyx of Held+++GO:0097433///dense body+++GO:0045335///phagocytic vesicle+++GO:0005884///actin filament+++GO:0072562///blood microparticle","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005522///profilin binding+++GO:0042802///identical protein binding","GO:0061024///membrane organization+++GO:0048488///synaptic vesicle endocytosis+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034329///cell junction assembly+++GO:0071346///cellular response to interferon-gamma+++GO:0048013///ephrin receptor signaling pathway+++GO:0070527///platelet aggregation+++GO:0001895///retina homeostasis+++GO:0045214///sarcomere organization","actin gamma 1","[ACTG_HUMAN|Reviewed]RecName: Full=Actin, cytoplasmic 2; AltName: Full=Gamma-actin; Contains: RecName: Full=Actin, cytoplasmic 2, N-terminally processed;+++[I3L1U9_HUMAN|Unreviewed]SubName: Full=Actin, cytoplasmic 2 {ECO:0000313|Ensembl:ENSP00000459119}; Flags: Fragment;+++[I3L3I0_HUMAN|Unreviewed]SubName: Full=Actin, cytoplasmic 2 {ECO:0000313|Ensembl:ENSP00000460464}; Flags: Fragment;+++[I3L3R2_HUMAN|Unreviewed]SubName: Full=Actin, cytoplasmic 2 {ECO:0000313|Ensembl:ENSP00000460660}; Flags: Fragment;+++[I3L4N8_HUMAN|Unreviewed]SubName: Full=Actin, cytoplasmic 2 {ECO:0000313|Ensembl:ENSP00000461407}; Flags: Fragment;+++[J3KT65_HUMAN|Unreviewed]SubName: Full=Actin, cytoplasmic 2 {ECO:0000313|Ensembl:ENSP00000462823};+++[K7EM38_HUMAN|Unreviewed]SubName: Full=Actin, cytoplasmic 2 {ECO:0000313|Ensembl:ENSP00000466346}; Flags: Fragment;+++[Q6PJ43_HUMAN|Unreviewed]SubName: Full=ACTG1 protein {ECO:0000313|EMBL:AAH23548.1}; Flags: Fragment;+++[Q96FU6_HUMAN|Unreviewed]SubName: Full=ACTG1 protein {ECO:0000313|EMBL:AAH10417.2}; Flags: Fragment;+++[V9HVZ7_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 176 {ECO:0000313|EMBL:ACF94484.1};"]
[7114,"'TMSB4X'",9713,10612,8181,9502,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0031093///platelet alpha granule lumen+++GO:0005576///extracellular region+++GO:0005622///intracellular+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0003779///actin binding+++GO:0019899///enzyme binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003785///actin monomer binding","GO:0050727///regulation of inflammatory response+++GO:1905273///positive regulation of proton-transporting ATP synthase activity, rotational mechanism+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0042989///sequestering of actin monomers+++GO:2000483///negative regulation of interleukin-8 secretion+++GO:2001028///positive regulation of endothelial cell chemotaxis+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:1903026///negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:2001171///positive regulation of ATP biosynthetic process+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0002576///platelet degranulation+++GO:0007015///actin filament organization+++GO:0030334///regulation of cell migration+++GO:0007253///cytoplasmic sequestering of NF-kappaB","thymosin beta 4 X-linked","[TYB4_HUMAN|Reviewed]RecName: Full=Thymosin beta-4; Short=T beta-4; AltName: Full=Fx; Contains: RecName: Full=Hematopoietic system regulatory peptide; AltName: Full=Seraspenide;+++[A2VCK8_HUMAN|Unreviewed]SubName: Full=Thymosin beta 4, X-linked {ECO:0000313|EMBL:AAI28103.1}; SubName: Full=Thymosin, beta 4, X-linked, isoform CRA_a {ECO:0000313|EMBL:EAW98810.1}; SubName: Full=cDNA, FLJ92006, Homo sapiens thymosin, beta 4, X chromosome (TMSB4X), mRNA {ECO:0000313|EMBL:BAG34690.1};+++[Q0P5N8_HUMAN|Unreviewed]SubName: Full=TMSB4X protein {ECO:0000313|EMBL:AAI04667.1}; Flags: Fragment;+++[Q0P5P4_HUMAN|Unreviewed]SubName: Full=TMSB4X protein {ECO:0000313|EMBL:AAH92437.1}; Flags: Fragment;+++[Q0P5Q0_HUMAN|Unreviewed]SubName: Full=TMSB4X protein {ECO:0000313|EMBL:AAH83509.1}; Flags: Fragment;+++[Q0P5T0_HUMAN|Unreviewed]SubName: Full=TMSB4X protein {ECO:0000313|EMBL:AAH64954.1}; Flags: Fragment;+++[Q0P5U7_HUMAN|Unreviewed]SubName: Full=TMSB4X protein {ECO:0000313|EMBL:AAH61586.1}; Flags: Fragment;"]
[7142,"'TNP2'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0000788///nuclear nucleosome+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0010954///positive regulation of protein processing+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0007341///penetration of zona pellucida+++GO:0030154///cell differentiation+++GO:0007275///multicellular organism development+++GO:0007340///acrosome reaction+++GO:0007283///spermatogenesis","transition protein 2","[STP2_HUMAN|Reviewed]RecName: Full=Nuclear transition protein 2; Short=TP-2; Short=TP2;+++[A0A2R8Y7P0_HUMAN|Unreviewed]RecName: Full=Nuclear transition protein 2 {ECO:0000256|RuleBase:RU000530};+++[Q4VB54_HUMAN|Unreviewed]RecName: Full=Nuclear transition protein 2 {ECO:0000256|RuleBase:RU000530};+++[Q4VB56_HUMAN|Unreviewed]RecName: Full=Nuclear transition protein 2 {ECO:0000256|RuleBase:RU000530};"]
[7165,"'TPD52L2'",2364,2516,2166,2348.66666666667,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm","GO:0003824///catalytic activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity","GO:0042127///regulation of cell proliferation","TPD52 like 2","[TPD54_HUMAN|Reviewed]RecName: Full=Tumor protein D54; Short=hD54; AltName: Full=Tumor protein D52-like 2;+++[A0A087WYR3_HUMAN|Unreviewed]SubName: Full=Tumor protein D54 {ECO:0000313|Ensembl:ENSP00000482024};+++[A0A087WZ51_HUMAN|Unreviewed]SubName: Full=Tumor protein D54 {ECO:0000313|Ensembl:ENSP00000482370};+++[Q68E05_HUMAN|Unreviewed]SubName: Full=Tumor protein D52-like 2, isoform CRA_f {ECO:0000313|EMBL:EAW75200.1}; SubName: Full=cDNA FLJ54053, highly similar to Homo sapiens tumor protein D52-like 2 (TPD52L2), transcript variant 6, mRNA {ECO:0000313|EMBL:BAG59585.1};+++[Q6FGS1_HUMAN|Unreviewed]SubName: Full=TPD52L2 protein {ECO:0000313|EMBL:CAG46833.1}; SubName: Full=Tumor protein D52-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW75194.1}; SubName: Full=cDNA, FLJ95317, highly similar to Homo sapiens tumor protein D52-like 2 (TPD52L2), mRNA {ECO:0000313|EMBL:BAG37101.1};"]
[7184,"'HSP90B1'",25779,22181,22089,23349.6666666667,"04918///Thyroid hormone synthesis+++05200///Pathways in cancer+++04626///Plant-pathogen interaction+++05215///Prostate cancer+++04141///Protein processing in endoplasmic reticulum+++04657///IL-17 signaling pathway+++04915///Estrogen signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0062023///collagen-containing extracellular matrix+++GO:0032991///protein-containing complex+++GO:0071682///endocytic vesicle lumen+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005576///extracellular region+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0042470///melanosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0030496///midbody","GO:0051082///unfolded protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0019903///protein phosphatase binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding","GO:0015031///protein transport+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0036500///ATF6-mediated unfolded protein response+++GO:0002224///toll-like receptor signaling pathway+++GO:0071318///cellular response to ATP+++GO:0043066///negative regulation of apoptotic process+++GO:0006898///receptor-mediated endocytosis+++GO:0043687///post-translational protein modification+++GO:0031247///actin rod assembly+++GO:0001666///response to hypoxia+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0034976///response to endoplasmic reticulum stress+++GO:0006457///protein folding+++GO:0019221///cytokine-mediated signaling pathway+++GO:0051208///sequestering of calcium ion+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0044267///cellular protein metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway","heat shock protein 90 beta family member 1","[ENPL_HUMAN|Reviewed]RecName: Full=Endoplasmin; AltName: Full=94 kDa glucose-regulated protein; Short=GRP-94; AltName: Full=Heat shock protein 90 kDa beta member 1; AltName: Full=Tumor rejection antigen 1; AltName: Full=gp96 homolog; Flags: Precursor;+++[A0A1W2PRR1_HUMAN|Unreviewed]SubName: Full=Endoplasmin {ECO:0000313|Ensembl:ENSP00000492386};+++[F8VPC7_HUMAN|Unreviewed]SubName: Full=Endoplasmin {ECO:0000313|Ensembl:ENSP00000446266};+++[F8W026_HUMAN|Unreviewed]SubName: Full=Endoplasmin {ECO:0000313|Ensembl:ENSP00000446748}; Flags: Fragment;+++[H0YIV0_HUMAN|Unreviewed]SubName: Full=Endoplasmin {ECO:0000313|Ensembl:ENSP00000450215}; Flags: Fragment;+++[Q96GW1_HUMAN|Unreviewed]SubName: Full=Endoplasmin {ECO:0000313|Ensembl:ENSP00000477660}; SubName: Full=HSP90B1 protein {ECO:0000313|EMBL:AAH09195.1};+++[V9HWP2_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 35 {ECO:0000313|EMBL:ACJ13662.1}; SubName: Full=Epididymis secretory sperm binding protein Li 125m {ECO:0000313|EMBL:ACS44652.1}; SubName: Full=Heat shock protein 90kDa beta (Grp94), member 1, isoform CRA_b {ECO:0000313|EMBL:EAW97724.1};"]
[7216,"'TRO'",949,823,912,894.666666666667,"04722///Neurotrophin signaling pathway",{"$nulls":3},"GO:0031226///intrinsic component of plasma membrane","GO:0005515///protein binding","GO:0007566///embryo implantation+++GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","trophinin","[TROP_HUMAN|Reviewed]RecName: Full=Trophinin; AltName: Full=MAGE-D3 antigen;+++[A0A024R9X0_HUMAN|Unreviewed]SubName: Full=Trophinin, isoform CRA_a {ECO:0000313|EMBL:EAW93201.1};+++[A0A087X070_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000483142};+++[B1AKE6_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000404767}; Flags: Fragment;+++[B1AKE7_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000406574}; Flags: Fragment;+++[B1AKE8_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000407996}; Flags: Fragment;+++[B1AKF2_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000412588}; Flags: Fragment;+++[B1AKF3_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000387676}; Flags: Fragment;+++[B1AKF4_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000392841}; Flags: Fragment;+++[B1AKF5_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000411717}; Flags: Fragment;+++[B1AKF6_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000388947}; Flags: Fragment;+++[B4DK08_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59555, highly similar to Trophinin {ECO:0000313|EMBL:BAG59020.1};+++[E7ERU6_HUMAN|Unreviewed]SubName: Full=Trophinin {ECO:0000313|Ensembl:ENSP00000405311}; Flags: Fragment;+++[G5E9N2_HUMAN|Unreviewed]SubName: Full=Trophinin, isoform CRA_c {ECO:0000313|EMBL:EAW93203.1};+++[Q9BX88_HUMAN|Unreviewed]SubName: Full=Magphinin delta {ECO:0000313|EMBL:AAK30173.1};+++[Q9BX89_HUMAN|Unreviewed]SubName: Full=Magphinin gamma {ECO:0000313|EMBL:AAK30172.1};+++[Q9BX90_HUMAN|Unreviewed]SubName: Full=Magphinin beta {ECO:0000313|EMBL:AAK30171.1};+++[Q9BX91_HUMAN|Unreviewed]SubName: Full=Magphinin alpha {ECO:0000313|EMBL:AAK30170.1};"]
[7265,"'TTC1'",1141,1015,975,1043.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005778///peroxisomal membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0051082///unfolded protein binding","GO:0006457///protein folding","tetratricopeptide repeat domain 1","[TTC1_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 1; Short=TPR repeat protein 1;+++[H0YB37_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 1 {ECO:0000313|Ensembl:ENSP00000428613}; Flags: Fragment;"]
[727800,"'RNF208'",467,511,479,485.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:0051865///protein autoubiquitination","ring finger protein 208","[RN208_HUMAN|Reviewed]RecName: Full=RING finger protein 208;"]
[727866,"'FAM156B'",319.58,255.69,279.59,284.953333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005635///nuclear envelope","GO:0035064///methylated histone binding",null,"family with sequence similarity 156 member B","[FA156_HUMAN|Reviewed]RecName: Full=Protein FAM156A/FAM156B; AltName: Full=Transmembrane protein 29/29B;+++[A0A087WZE8_HUMAN|Unreviewed]SubName: Full=Protein FAM156A/FAM156B {ECO:0000313|Ensembl:ENSP00000482608}; Flags: Fragment;+++[A0A087X2H2_HUMAN|Unreviewed]SubName: Full=Protein FAM156A/FAM156B {ECO:0000313|Ensembl:ENSP00000484983}; Flags: Fragment;"]
[728485,"'LOC728485'",12,21,7,13.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"uncharacterized LOC728485","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[NEK4_HUMAN|diamond]RecName: Full=Serine/threonine-protein kinase Nek4; EC=2.7.11.1 {ECO:0000250|UniProtKB:Q9Z1J2}; AltName: Full=Never in mitosis A-related kinase 4; Short=NimA-related protein kinase 4; AltName: Full=Serine/threonine-protein kinase 2; AltName: Full=Serine/threonine-protein kinase NRK2;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[728577,"'CNTNAP3B'",84.55,78.86,77.27,80.2266666666667,"04514///Cell adhesion molecules (CAMs)","H02111///Autism+++H00756///Pitt-Hopkins syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:0007155///cell adhesion","contactin associated protein like 3B","[CNT3B_HUMAN|Reviewed]RecName: Full=Contactin-associated protein-like 3B; AltName: Full=Cell recognition molecule Caspr3b; Flags: Precursor;+++[A0A087WUG9_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000478659};+++[A0A087WXL9_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000481131};+++[A0A087WZ03_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000482254};+++[A0A087X0T4_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000483642}; Flags: Fragment;+++[A0A087X119_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000483830};+++[A0A087X2E4_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000484919}; Flags: Fragment;+++[A0A2P0CT92_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000276974};+++[F2Z2X5_HUMAN|Unreviewed]SubName: Full=Contactin-associated protein-like 3B {ECO:0000313|Ensembl:ENSP00000432883};"]
[729085,"'FAM198A'",6,5,1,4,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region","GO:0003677///DNA binding",null,"family with sequence similarity 198 member A","[F198A_HUMAN|Reviewed]RecName: Full=Protein FAM198A; Flags: Precursor;+++[F5H4W4_HUMAN|Unreviewed]SubName: Full=Protein FAM198A {ECO:0000313|Ensembl:ENSP00000439905}; Flags: Fragment;"]
[729288,"'ZNF286B'",39.2,57.37,47.91,48.16,"04722///Neurotrophin signaling pathway+++04218///Cellular senescence+++04211///Longevity regulating pathway+++04152///AMPK signaling pathway+++04212///Longevity regulating pathway - worm+++05223///Non-small cell lung cancer+++04917///Prolactin signaling pathway+++04137///Mitophagy - animal+++01521///EGFR tyrosine kinase inhibitor resistance+++04151///PI3K-Akt signaling pathway+++04062///Chemokine signaling pathway+++04213///Longevity regulating pathway - multiple species+++05213///Endometrial cancer+++04068///FoxO signaling pathway","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation","M00676///PI3K-Akt signaling",null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 286B","[Z286B_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 286B;+++[A0A2Z4LIS9_HUMAN|Unreviewed]SubName: Full=Forkhead box O3B {ECO:0000313|EMBL:AWX41297.1};+++[I3L365_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 286B {ECO:0000313|Ensembl:ENSP00000460210};+++[I3L3U3_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 286B {ECO:0000313|Ensembl:ENSP00000460736}; Flags: Fragment;+++[J3KS91_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 286B {ECO:0000313|Ensembl:ENSP00000462368}; Flags: Fragment;+++[J3QKZ1_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 286B {ECO:0000313|Ensembl:ENSP00000463300}; Flags: Fragment;"]
[729978,"'NPIPB2'",20.25,32.66,52.71,35.2066666666667,"04672///Intestinal immune network for IgA production+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005654///nucleoplasm","GO:0035091///phosphatidylinositol binding",null,"nuclear pore complex interacting protein family, member B2","[A0A087WUS9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family, member B2 {ECO:0000313|Ensembl:ENSP00000478897};+++[F5H898_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family, member B2 {ECO:0000313|Ensembl:ENSP00000442069}; Flags: Fragment;+++[F8VY45_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family, member B2 {ECO:0000313|Ensembl:ENSP00000448752}; Flags: Fragment;"]
[730098,"'LOC730098'",25,18,24,22.3333333333333,"04060///Cytokine-cytokine receptor interaction+++04062///Chemokine signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0031728///CCR3 chemokine receptor binding+++GO:0008009///chemokine activity","GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0031640///killing of cells of other organism+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0006955///immune response+++GO:0006935///chemotaxis","uncharacterized LOC730098","[B7Z3J9_HUMAN|Unreviewed]SubName: Full=HCG2040265, isoform CRA_a {ECO:0000313|EMBL:EAW58418.1}; SubName: Full=cDNA FLJ50015 {ECO:0000313|EMBL:BAH12235.1};+++[H3BQ31_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000455581};"]
[7326,"'UBE2G1'",736,676,758,723.333333333333,"05012///Parkinson's disease+++04141///Protein processing in endoplasmic reticulum+++04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0031625///ubiquitin protein ligase binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0000209///protein polyubiquitination+++GO:0044257///cellular protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0070936///protein K48-linked ubiquitination","ubiquitin conjugating enzyme E2 G1","[UB2G1_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 G1; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme G1; AltName: Full=E217K; AltName: Full=UBC7; AltName: Full=Ubiquitin carrier protein G1; AltName: Full=Ubiquitin-protein ligase G1; Contains: RecName: Full=Ubiquitin-conjugating enzyme E2 G1, N-terminally processed;+++[I3L0Q0_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 G1 {ECO:0000313|Ensembl:ENSP00000458253};+++[I3L2H7_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 G1 {ECO:0000313|Ensembl:ENSP00000459691};+++[I3L2Q4_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 G1 {ECO:0000313|Ensembl:ENSP00000459847};+++[K7EPR7_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 G1 {ECO:0000313|Ensembl:ENSP00000467502}; SubName: Full=Ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast), isoform CRA_a {ECO:0000313|EMBL:EAW90441.1}; Flags: Fragment;"]
[7337,"'UBE3A'",1021,870,881,924,"05165///Human papillomavirus infection+++05203///Viral carcinogenesis+++04120///Ubiquitin mediated proteolysis","H01732///Angelman syndrome (AS)",null,null,"GO:0005634///nucleus+++GO:0000502///proteasome complex+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016874///ligase activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity","GO:0042752///regulation of circadian rhythm+++GO:0051865///protein autoubiquitination+++GO:0000209///protein polyubiquitination+++GO:0006508///proteolysis+++GO:0007420///brain development+++GO:0050847///progesterone receptor signaling pathway+++GO:0048511///rhythmic process+++GO:0016032///viral process+++GO:0016567///protein ubiquitination+++GO:0032570///response to progesterone+++GO:0070936///protein K48-linked ubiquitination+++GO:2000058///regulation of ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process","ubiquitin protein ligase E3A","[UBE3A_HUMAN|Reviewed]RecName: Full=Ubiquitin-protein ligase E3A; EC=2.3.2.26 {ECO:0000269|PubMed:24273172}; AltName: Full=E6AP ubiquitin-protein ligase {ECO:0000303|PubMed:17108031}; AltName: Full=HECT-type ubiquitin transferase E3A; AltName: Full=Human papillomavirus E6-associated protein {ECO:0000303|PubMed:8380895}; AltName: Full=Oncogenic protein-associated protein E6-AP {ECO:0000303|PubMed:8380895}; AltName: Full=Renal carcinoma antigen NY-REN-54;+++[A0A0D9SEJ2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000485732}; Flags: Fragment;+++[A0A0D9SES7_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000485958}; Flags: Fragment;+++[A0A0D9SF91_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486388}; Flags: Fragment;+++[A0A0D9SFH3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486601}; Flags: Fragment;+++[A0A0D9SFU3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486900}; Flags: Fragment;+++[A0A0D9SG54_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487148}; Flags: Fragment;+++[A0A0D9SG63_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487178}; Flags: Fragment;+++[A0A0D9SG77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487217};+++[A0A0D9SGI3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487534}; Flags: Fragment;+++[A0A0D9SGJ0_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000487550}; Flags: Fragment;+++[A0A0G2JQQ5_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000486066}; Flags: Fragment;+++[A0A1B0GTB3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000489625};+++[A0A1B0GVL3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000490563};+++[Q5W7F7_HUMAN|Unreviewed]SubName: Full=Ubiquitin ligase E3A isoform 1 {ECO:0000313|EMBL:BAD69554.1};+++[Q96GR7_HUMAN|Unreviewed]SubName: Full=UBE3A protein {ECO:0000313|EMBL:AAH09271.1};+++[Q9BUI6_HUMAN|Unreviewed]SubName: Full=Ubiquitin protein ligase E3A {ECO:0000313|EMBL:AAH02582.2};+++[Q9H2G0_HUMAN|Unreviewed]SubName: Full=CTCL tumor antigen se37-2 {ECO:0000313|EMBL:AAG34910.1}; SubName: Full=Ubiquitin protein ligase E3A (Human papilloma virus E6-associated protein, Angelman syndrome), isoform CRA_b {ECO:0000313|EMBL:EAW57643.1}; SubName: Full=cDNA FLJ77551, highly similar to Homo sapiens ubiquitin protein ligase E3A (human papilloma virus E6-associated protein, Angelman syndrome) (UBE3A), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84094.1};+++[Q9UBN9_HUMAN|Unreviewed]SubName: Full=E6-AP ubiquitin-protein ligase {ECO:0000313|EMBL:AAC39580.1}; Flags: Fragment;+++[S4R306_HUMAN|Unreviewed]SubName: Full=Ubiquitin-protein ligase E3A {ECO:0000313|Ensembl:ENSP00000473822}; Flags: Fragment;"]
[7349,"'UCN'",8,8,9,8.33333333333333,{"$nulls":4},"GO:0043196///varicosity+++GO:0043204///perikaryon+++GO:0030425///dendrite+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0030424///axon+++GO:0043679///axon terminus+++GO:0043025///neuronal cell body","GO:0005179///hormone activity+++GO:0051431///corticotropin-releasing hormone receptor 2 binding+++GO:0051430///corticotropin-releasing hormone receptor 1 binding+++GO:0005184///neuropeptide hormone activity+++GO:0005515///protein binding+++GO:0001664///G protein-coupled receptor binding+++GO:0017045///corticotropin-releasing hormone activity+++GO:0046811///histone deacetylase inhibitor activity","GO:0060455///negative regulation of gastric acid secretion+++GO:2000252///negative regulation of feeding behavior+++GO:0045792///negative regulation of cell size+++GO:0035176///social behavior+++GO:0046888///negative regulation of hormone secretion+++GO:0035483///gastric emptying+++GO:0030307///positive regulation of cell growth+++GO:0048265///response to pain+++GO:0010628///positive regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008306///associative learning+++GO:0001964///startle response+++GO:0032811///negative regulation of epinephrine secretion+++GO:0051384///response to glucocorticoid+++GO:0045727///positive regulation of translation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010469///regulation of signaling receptor activity+++GO:0031175///neuron projection development+++GO:0070093///negative regulation of glucagon secretion+++GO:0032099///negative regulation of appetite+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0030157///pancreatic juice secretion+++GO:0045776///negative regulation of blood pressure+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0051461///positive regulation of corticotropin secretion+++GO:0043066///negative regulation of apoptotic process+++GO:0032355///response to estradiol+++GO:1901215///negative regulation of neuron death+++GO:2000987///positive regulation of behavioral fear response+++GO:0034199///activation of protein kinase A activity+++GO:0043117///positive regulation of vascular permeability+++GO:0032755///positive regulation of interleukin-6 production+++GO:0007218///neuropeptide signaling pathway+++GO:0006979///response to oxidative stress+++GO:0097755///positive regulation of blood vessel diameter+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0010629///negative regulation of gene expression+++GO:0007611///learning or memory+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0006954///inflammatory response+++GO:0060547///negative regulation of necrotic cell death+++GO:0009060///aerobic respiration+++GO:0007631///feeding behavior+++GO:0051464///positive regulation of cortisol secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0010996///response to auditory stimulus+++GO:0031064///negative regulation of histone deacetylation+++GO:0007605///sensory perception of sound+++GO:0060548///negative regulation of cell death+++GO:0045740///positive regulation of DNA replication+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0042756///drinking behavior+++GO:0007565///female pregnancy+++GO:0090280///positive regulation of calcium ion import","urocortin","[UCN1_HUMAN|Reviewed]RecName: Full=Urocortin; Flags: Precursor;"]
[7386,"'UQCRFS1'",890,1030,954,958,"05012///Parkinson's disease+++04714///Thermogenesis+++02020///Two-component system+++00190///Oxidative phosphorylation+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05010///Alzheimer's disease+++01100///Metabolic pathways+++05016///Huntington's disease+++04260///Cardiac muscle contraction",null,"M00152///Cytochrome bc1 complex+++M00151///Cytochrome bc1 complex respiratory unit",null,"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0070469///respiratory chain+++GO:0005751///mitochondrial respiratory chain complex IV+++GO:0031966///mitochondrial membrane","GO:0046872///metal ion binding+++GO:0008121///ubiquinol-cytochrome-c reductase activity+++GO:0044877///protein-containing complex binding+++GO:0016679///oxidoreductase activity, acting on diphenols and related substances as donors+++GO:0051536///iron-sulfur cluster binding+++GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0051537///2 iron, 2 sulfur cluster binding","GO:0009725///response to hormone+++GO:0046677///response to antibiotic+++GO:0055114///oxidation-reduction process+++GO:0042493///response to drug+++GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c","ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1","[UCRI_HUMAN|Reviewed]RecName: Full=Cytochrome b-c1 complex subunit Rieske, mitochondrial; EC=1.10.2.2; AltName: Full=Complex III subunit 5; AltName: Full=Cytochrome b-c1 complex subunit 5; AltName: Full=Rieske iron-sulfur protein; Short=RISP; AltName: Full=Rieske protein UQCRFS1 {ECO:0000305}; AltName: Full=Ubiquinol-cytochrome c reductase iron-sulfur subunit; Contains: RecName: Full=Cytochrome b-c1 complex subunit 9 {ECO:0000250|UniProtKB:P13272}; Short=Su9 {ECO:0000250|UniProtKB:P13272}; Short=Subunit 9 {ECO:0000250|UniProtKB:P13272}; AltName: Full=8 kDa subunit 9 {ECO:0000250|UniProtKB:P13272}; AltName: Full=Complex III subunit IX; AltName: Full=Cytochrome b-c1 complex subunit 11; AltName: Full=Ubiquinol-cytochrome c reductase 8 kDa protein {ECO:0000250|UniProtKB:P13272}; Flags: Precursor;"]
[7399,"'USH2A'",11,6,3,6.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00527///Retinitis pigmentosa (RP)+++H00779///Usher syndrome (US)",null,null,"GO:0032391///photoreceptor connecting cilium+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:1990696///USH2 complex+++GO:0016020///membrane+++GO:1990075///periciliary membrane compartment+++GO:0016021///integral component of membrane+++GO:0002142///stereocilia ankle link complex+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0043195///terminal bouton+++GO:0002141///stereocilia ankle link+++GO:0060171///stereocilium membrane+++GO:0032421///stereocilium bundle+++GO:0005576///extracellular region+++GO:0036064///ciliary basal body+++GO:0001917///photoreceptor inner segment+++GO:0043025///neuronal cell body","GO:0005518///collagen binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0017022///myosin binding","GO:0060113///inner ear receptor cell differentiation+++GO:0050953///sensory perception of light stimulus+++GO:0048496///maintenance of animal organ identity+++GO:0007601///visual perception+++GO:0035315///hair cell differentiation+++GO:0007605///sensory perception of sound+++GO:0045494///photoreceptor cell maintenance+++GO:0050896///response to stimulus+++GO:0045184///establishment of protein localization","usherin","[USH2A_HUMAN|Reviewed]RecName: Full=Usherin; AltName: Full=Usher syndrome type IIa protein; AltName: Full=Usher syndrome type-2A protein; Flags: Precursor;"]
[7431,"'VIM'",162893,165061,144684,157546,"05169///Epstein-Barr virus infection+++05206///MicroRNAs in cancer","H01202///Cataract",null,null,"GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:1990904///ribonucleoprotein complex+++GO:0005777///peroxisome+++GO:0031252///cell leading edge+++GO:0005844///polysome+++GO:0043005///neuron projection+++GO:0005925///focal adhesion+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005882///intermediate filament+++GO:0045335///phagocytic vesicle","GO:0003725///double-stranded RNA binding+++GO:1990254///keratin filament binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0097110///scaffold protein binding+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005198///structural molecule activity+++GO:0019904///protein domain specific binding","GO:0045109///intermediate filament organization+++GO:0060395///SMAD protein signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0071346///cellular response to interferon-gamma+++GO:0045727///positive regulation of translation+++GO:0014002///astrocyte development+++GO:0045103///intermediate filament-based process+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0043488///regulation of mRNA stability+++GO:0071222///cellular response to lipopolysaccharide+++GO:0016032///viral process+++GO:0030049///muscle filament sliding+++GO:0071225///cellular response to muramyl dipeptide+++GO:0070307///lens fiber cell development+++GO:0010628///positive regulation of gene expression+++GO:0010977///negative regulation of neuron projection development+++GO:0060020///Bergmann glial cell differentiation","vimentin","[VIME_HUMAN|Reviewed]RecName: Full=Vimentin;+++[A0A0S2Z4T0_HUMAN|Unreviewed]SubName: Full=Vimentin isoform 2 {ECO:0000313|EMBL:ALQ33847.1};+++[A0A1B0GTT5_HUMAN|Unreviewed]SubName: Full=Vimentin {ECO:0000313|Ensembl:ENSP00000489830}; Flags: Fragment;+++[A0A1B0GVG8_HUMAN|Unreviewed]SubName: Full=Vimentin {ECO:0000313|Ensembl:ENSP00000490509}; Flags: Fragment;+++[B0YJC4_HUMAN|Unreviewed]SubName: Full=Vimentin variant 3 {ECO:0000313|EMBL:ACA06103.1};+++[B0YJC5_HUMAN|Unreviewed]SubName: Full=Vimentin variant 4 {ECO:0000313|EMBL:ACA06100.1};+++[V9HWE1_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 113 {ECO:0000313|EMBL:ACJ13726.1}; SubName: Full=Vimentin isoform 1 {ECO:0000313|EMBL:ALQ33846.1};"]
[7439,"'BEST1'",6730,5563,15740,9344.33333333333,"04978///Mineral absorption+++04216///Ferroptosis+++04217///Necroptosis","H02078///Autosomal dominant vitreoretinochoroidopathy+++H00814///Vitelliform macular dystrophy+++H00805///Vitreoretinal degeneration+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0034707///chloride channel complex+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005254///chloride channel activity+++GO:0005229///intracellular calcium activated chloride channel activity+++GO:0015106///bicarbonate transmembrane transporter activity","GO:0030321///transepithelial chloride transport+++GO:0015701///bicarbonate transport+++GO:0006811///ion transport+++GO:0007601///visual perception+++GO:1902476///chloride transmembrane transport+++GO:0050896///response to stimulus+++GO:0006821///chloride transport+++GO:0051924///regulation of calcium ion transport+++GO:0050908///detection of light stimulus involved in visual perception+++GO:0034220///ion transmembrane transport","bestrophin 1","[BEST1_HUMAN|Reviewed]RecName: Full=Bestrophin-1; AltName: Full=TU15B; AltName: Full=Vitelliform macular dystrophy protein 2;+++[A0A0C4DGE9_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126};+++[A0A0S2Z4J9_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126}; Flags: Fragment;+++[A0A0S2Z4M4_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126}; Flags: Fragment;+++[A0A0S2Z4V3_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126};+++[A0A0S2Z579_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126}; Flags: Fragment;+++[A0A0S2Z5F4_HUMAN|Unreviewed]SubName: Full=Bestrophin 1 isoform 8 {ECO:0000313|EMBL:ALQ33852.1};+++[B7Z1N8_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126};+++[B7Z375_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126};+++[E9PMB5_HUMAN|Unreviewed]RecName: Full=Bestrophin {ECO:0000256|RuleBase:RU363126};"]
[7482,"'WNT2B'",247,206,206,219.666666666667,"04310///Wnt signaling pathway+++05217///Basal cell carcinoma+++04390///Hippo signaling pathway+++05166///HTLV-I infection+++04934///Cushing's syndrome+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05224///Breast cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++04916///Melanogenesis+++05226///Gastric cancer+++05205///Proteoglycans in cancer+++05225///Hepatocellular carcinoma+++04150///mTOR signaling pathway",null,"M00677///Wnt signaling",null,"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle","GO:0005102///signaling receptor binding+++GO:0005109///frizzled binding","GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0045165///cell fate commitment+++GO:0061303///cornea development in camera-type eye+++GO:0071425///hematopoietic stem cell proliferation+++GO:0060638///mesenchymal-epithelial cell signaling+++GO:0021871///forebrain regionalization+++GO:0007275///multicellular organism development+++GO:0061072///iris morphogenesis+++GO:0060492///lung induction+++GO:0009267///cellular response to starvation+++GO:0060070///canonical Wnt signaling pathway+++GO:0002062///chondrocyte differentiation+++GO:0016055///Wnt signaling pathway+++GO:0008584///male gonad development+++GO:0002088///lens development in camera-type eye+++GO:0030182///neuron differentiation","Wnt family member 2B","[WNT2B_HUMAN|Reviewed]RecName: Full=Protein Wnt-2b; AltName: Full=Protein Wnt-13 {ECO:0000303|PubMed:8761309}; Flags: Precursor;+++[Q5TEH8_HUMAN|Unreviewed]RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};"]
[7486,"'WRN'",105.04,81.05,87,91.03,null,"H01733///Werner syndrome+++H00296///Defects in RecQ helicases",null,null,"GO:0000781///chromosome, telomeric region+++GO:0005657///replication fork+++GO:0005662///DNA replication factor A complex+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm+++GO:0032389///MutLalpha complex+++GO:0043005///neuron projection+++GO:0005813///centrosome+++GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0005694///chromosome+++GO:0005654///nucleoplasm","GO:0032405///MutLalpha complex binding+++GO:0043140///ATP-dependent 3'-5' DNA helicase activity+++GO:0000405///bubble DNA binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0003678///DNA helicase activity+++GO:0051880///G-quadruplex DNA binding+++GO:0005524///ATP binding+++GO:0000403///Y-form DNA binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0061749///forked DNA-dependent helicase activity+++GO:0061849///telomeric G-quadruplex DNA binding+++GO:0008026///ATP-dependent helicase activity+++GO:0004386///helicase activity+++GO:0043138///3'-5' DNA helicase activity+++GO:0042803///protein homodimerization activity+++GO:0030145///manganese ion binding+++GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0009378///four-way junction helicase activity+++GO:0004527///exonuclease activity+++GO:0004518///nuclease activity+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000400///four-way junction DNA binding+++GO:0008408///3'-5' exonuclease activity+++GO:1905773///8-hydroxy-2'-deoxyguanosine DNA binding+++GO:0070337///3'-flap-structured DNA binding+++GO:0044877///protein-containing complex binding+++GO:0061821///telomeric D-loop binding","GO:0098530///positive regulation of strand invasion+++GO:0006259///DNA metabolic process+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0006260///DNA replication+++GO:0000723///telomere maintenance+++GO:0006284///base-excision repair+++GO:1902570///protein localization to nucleolus+++GO:0006310///DNA recombination+++GO:0044806///G-quadruplex DNA unwinding+++GO:0006302///double-strand break repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0008152///metabolic process+++GO:0008340///determination of adult lifespan+++GO:0032508///DNA duplex unwinding+++GO:0009267///cellular response to starvation+++GO:0006281///DNA repair+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0071480///cellular response to gamma radiation+++GO:0010259///multicellular organism aging+++GO:0051345///positive regulation of hydrolase activity+++GO:0007420///brain development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0061820///telomeric D-loop disassembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007569///cell aging+++GO:0001302///replicative cell aging+++GO:0090656///t-circle formation+++GO:0010225///response to UV-C+++GO:0044237///cellular metabolic process+++GO:0031297///replication fork processing+++GO:0042981///regulation of apoptotic process+++GO:0040009///regulation of growth rate+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","Werner syndrome RecQ like helicase","[WRN_HUMAN|Reviewed]RecName: Full=Werner syndrome ATP-dependent helicase; EC=3.6.4.12 {ECO:0000269|PubMed:16622405}; AltName: Full=DNA helicase, RecQ-like type 3; Short=RecQ3; AltName: Full=Exonuclease WRN; EC=3.1.-.-; AltName: Full=RecQ protein-like 2;"]
[7525,"'YES1'",344.11,236,273.26,284.456666666667,"04520///Adherens junction",{"$nulls":3},"GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0099091///postsynaptic specialization, intracellular component+++GO:0098978///glutamatergic synapse","GO:0001784///phosphotyrosine residue binding+++GO:0004713///protein tyrosine kinase activity+++GO:0019899///enzyme binding+++GO:0016301///kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005524///ATP binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0044325///ion channel binding+++GO:0005102///signaling receptor binding+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity","GO:0043114///regulation of vascular permeability+++GO:0006468///protein phosphorylation+++GO:0071300///cellular response to retinoic acid+++GO:0046777///protein autophosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0031295///T cell costimulation+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0016310///phosphorylation+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0006464///cellular protein modification process+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0048013///ephrin receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0010827///regulation of glucose transmembrane transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0050900///leukocyte migration+++GO:0030154///cell differentiation","YES proto-oncogene 1, Src family tyrosine kinase","[YES_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase Yes; EC=2.7.10.2; AltName: Full=Proto-oncogene c-Yes; AltName: Full=p61-Yes;+++[J3QRU1_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};+++[L8E9B9_HUMAN|Unreviewed]SubName: Full=Alternative protein YES1 {ECO:0000313|EMBL:CCQ43321.1};"]
[7541,"'ZBTB14'",83,51,86,73.3333333333333,{"$nulls":4},"GO:0016235///aggresome+++GO:0005829///cytosol+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003700///DNA-binding transcription factor activity+++GO:0003676///nucleic acid binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding","GO:0060976///coronary vasculature development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0003170///heart valve development+++GO:0003279///cardiac septum development+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger and BTB domain containing 14","[ZBT14_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 14; AltName: Full=Zinc finger protein 161 homolog; Short=Zfp-161; AltName: Full=Zinc finger protein 478; AltName: Full=Zinc finger protein 5 homolog; Short=ZF5; Short=Zfp-5; Short=hZF5;+++[B2R850_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93740, highly similar to Homo sapiens zinc finger protein 161 homolog (mouse) (ZFP161), mRNA {ECO:0000313|EMBL:BAG36047.1};+++[J3KRQ2_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000462112}; Flags: Fragment;+++[J3QL74_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000463414}; Flags: Fragment;+++[J3QLI2_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000463555}; Flags: Fragment;"]
[7564,"'ZNF16'",71,81,64,72,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0043066///negative regulation of apoptotic process+++GO:0045654///positive regulation of megakaryocyte differentiation+++GO:1901989///positive regulation of cell cycle phase transition+++GO:0008284///positive regulation of cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0072707///cellular response to sodium dodecyl sulfate+++GO:0033674///positive regulation of kinase activity+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0051781///positive regulation of cell division","zinc finger protein 16","[ZNF16_HUMAN|Reviewed]RecName: Full=Zinc finger protein 16; AltName: Full=Zinc finger protein KOX9;+++[E9PNT9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 16 {ECO:0000313|Ensembl:ENSP00000432755}; Flags: Fragment;+++[E9PQV1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 16 {ECO:0000313|Ensembl:ENSP00000434321}; Flags: Fragment;+++[L8EAK2_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF16 {ECO:0000313|EMBL:CCQ43383.1};"]
[7581,"'ZNF33A'",483,375,448.01,435.336666666667,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 33A","[ZN33A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 33A; AltName: Full=Zinc finger and ZAK-associated protein with KRAB domain; Short=ZZaPK; AltName: Full=Zinc finger protein 11A; AltName: Full=Zinc finger protein KOX31;+++[A0A0A0MR11_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 33A {ECO:0000313|Ensembl:ENSP00000304268};+++[A0A0A0MRS1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 33A {ECO:0000313|Ensembl:ENSP00000363747};+++[A0AUX1_HUMAN|Unreviewed]SubName: Full=ZNF33A protein {ECO:0000313|EMBL:AAI26120.1};+++[Q05D89_HUMAN|Unreviewed]SubName: Full=ZNF33A protein {ECO:0000313|EMBL:AAH17760.1}; Flags: Fragment;+++[Q8N6F5_HUMAN|Unreviewed]SubName: Full=ZNF33A protein {ECO:0000313|EMBL:AAH30511.1}; Flags: Fragment;+++[Q9H5I4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 33A, isoform CRA_c {ECO:0000313|EMBL:EAW85890.1}; SubName: Full=cDNA: FLJ23404 fis, clone HEP18862 {ECO:0000313|EMBL:BAB15642.1};"]
[7621,"'ZNF70'",139,126,141,135.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 70","[ZNF70_HUMAN|Reviewed]RecName: Full=Zinc finger protein 70; AltName: Full=Zinc finger protein N27C7-1;+++[B3KV76_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16219 fis, clone CTONG3002433, highly similar to Zinc finger protein 70 {ECO:0000313|EMBL:BAG53688.1};"]
[7675,"'ZNF121'",24,17,9,16.6666666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 121","[ZN121_HUMAN|Reviewed]RecName: Full=Zinc finger protein 121; AltName: Full=Zinc finger protein 20;+++[K7EQI1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 121 {ECO:0000313|Ensembl:ENSP00000467838}; Flags: Fragment;"]
[7700,"'ZNF141'",90.21,66.97,84,80.3933333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity","GO:0006366///transcription by RNA polymerase II+++GO:0035108///limb morphogenesis+++GO:0009653///anatomical structure morphogenesis","zinc finger protein 141","[ZN141_HUMAN|Reviewed]RecName: Full=Zinc finger protein 141;+++[D6RIY0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 141 (Clone pHZ-44), isoform CRA_c {ECO:0000313|EMBL:EAW82671.1};+++[Q4W5N2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZNF141 {ECO:0000313|EMBL:AAY41036.1}; Flags: Fragment;"]
[7728,"'ZNF175'",145,112,121,126,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0045111///intermediate filament cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0051607///defense response to virus+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 175","[ZN175_HUMAN|Reviewed]RecName: Full=Zinc finger protein 175; AltName: Full=Zinc finger protein OTK18;+++[F5GZI7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 175 {ECO:0000313|Ensembl:ENSP00000444424};+++[G3V1K8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 175 {ECO:0000313|Ensembl:ENSP00000440578}; SubName: Full=Zinc finger protein 175, isoform CRA_a {ECO:0000313|EMBL:EAW72029.1};+++[L8E9H5_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF175 {ECO:0000313|EMBL:CCQ43391.1};+++[M0R013_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 175 {ECO:0000313|Ensembl:ENSP00000470922};"]
[7750,"'ZMYM2'",830,528,581,646.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0005829///cytosol","GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding+++GO:0004713///protein tyrosine kinase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0022604///regulation of cell morphogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0008150///biological_process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization","zinc finger MYM-type containing 2","[ZMYM2_HUMAN|Reviewed]RecName: Full=Zinc finger MYM-type protein 2; AltName: Full=Fused in myeloproliferative disorders protein; AltName: Full=Rearranged in atypical myeloproliferative disorder protein; AltName: Full=Zinc finger protein 198;+++[A0A024RDS3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 198, isoform CRA_b {ECO:0000313|EMBL:EAX08245.1};+++[A0A087X151_HUMAN|Unreviewed]SubName: Full=Zinc finger MYM-type protein 2 {ECO:0000313|Ensembl:ENSP00000483904}; Flags: Fragment;+++[A8K126_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76647, highly similar to Homo sapiens zinc finger protein 198 (ZNF198), mRNA {ECO:0000313|EMBL:BAF82430.1}; Flags: Fragment;"]
[7771,"'ZNF112'",65,63,65,64.3333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 112","[ZN112_HUMAN|Reviewed]RecName: Full=Zinc finger protein 112; Short=Zfp-112; AltName: Full=Zinc finger protein 228;+++[K7EIR6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000464862};+++[K7EN57_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000466797}; Flags: Fragment;+++[K7ENS0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000467064}; Flags: Fragment;+++[K7EQV5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000467994}; Flags: Fragment;+++[Q0VG01_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 homolog (Mouse) {ECO:0000313|EMBL:AAI17224.1};"]
[779,"'CACNA1S'",14,13,9,12,"04927///Cortisol synthesis and secretion+++04727///GABAergic synapse+++04925///Aldosterone synthesis and secretion+++04020///Calcium signaling pathway+++05410///Hypertrophic cardiomyopathy (HCM)+++04010///MAPK signaling pathway+++05010///Alzheimer's disease+++04261///Adrenergic signaling in cardiomyocytes+++04723///Retrograde endocannabinoid signaling+++04270///Vascular smooth muscle contraction+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04726///Serotonergic synapse+++04934///Cushing's syndrome+++05414///Dilated cardiomyopathy (DCM)+++04725///Cholinergic synapse+++04022///cGMP-PKG signaling pathway+++04924///Renin secretion+++04024///cAMP signaling pathway+++04911///Insulin secretion+++04912///GnRH signaling pathway+++04260///Cardiac muscle contraction+++04921///Oxytocin signaling pathway","H00746///Hypokalemic periodic paralysis (HypoPP)+++H00215///Periodic paralysis",null,null,"GO:0005891///voltage-gated calcium channel complex+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0042383///sarcolemma+++GO:1990454///L-type voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0031674///I band","GO:0008331///high voltage-gated calcium channel activity+++GO:0005216///ion channel activity+++GO:0046872///metal ion binding+++GO:0005262///calcium channel activity+++GO:0005515///protein binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005516///calmodulin binding","GO:0055085///transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0006936///muscle contraction+++GO:0070588///calcium ion transmembrane transport+++GO:0071313///cellular response to caffeine+++GO:0070509///calcium ion import","calcium voltage-gated channel subunit alpha1 S","[CAC1S_HUMAN|Reviewed]RecName: Full=Voltage-dependent L-type calcium channel subunit alpha-1S; AltName: Full=Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle; AltName: Full=Voltage-gated calcium channel subunit alpha Cav1.1;+++[B1ALM3_HUMAN|Unreviewed]RecName: Full=Voltage-dependent L-type calcium channel subunit alpha {ECO:0000256|RuleBase:RU003808};"]
[7841,"'MOGS'",1659,1735,1853,1749,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis+++04141///Protein processing in endoplasmic reticulum","H00119///Congenital disorders of glycosylation (CDG) type II","M00073///N-glycan precursor trimming","R05979///H2O + G00009 <=> beta-D-Glucose + G00171","GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0015926///glucosidase activity+++GO:0004573///mannosyl-oligosaccharide glucosidase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds","GO:0006457///protein folding+++GO:0008152///metabolic process+++GO:0006487///protein N-linked glycosylation+++GO:0009311///oligosaccharide metabolic process","mannosyl-oligosaccharide glucosidase","[MOGS_HUMAN|Reviewed]RecName: Full=Mannosyl-oligosaccharide glucosidase; EC=3.2.1.106; AltName: Full=Processing A-glucosidase I;+++[B8ZZE2_HUMAN|Unreviewed]SubName: Full=Mannosyl-oligosaccharide glucosidase {ECO:0000313|Ensembl:ENSP00000386493};+++[C9J8D4_HUMAN|Unreviewed]SubName: Full=Mannosyl-oligosaccharide glucosidase {ECO:0000313|Ensembl:ENSP00000410992}; Flags: Fragment;+++[C9JDQ1_HUMAN|Unreviewed]SubName: Full=Mannosyl-oligosaccharide glucosidase {ECO:0000313|Ensembl:ENSP00000396298}; Flags: Fragment;+++[Q58F09_HUMAN|Unreviewed]SubName: Full=Glucosidase I {ECO:0000313|EMBL:AAH28337.1};"]
[7867,"'MAPKAPK3'",1526,1549,1545,1540,"04010///MAPK signaling pathway+++04370///VEGF signaling pathway","H01890///Pattern dystrophies of the retinal pigment epithelium","M00388///ECS complex+++M00684///JAK-STAT signaling",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0051019///mitogen-activated protein kinase binding+++GO:0004708///MAP kinase kinase activity+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0032496///response to lipopolysaccharide+++GO:0007165///signal transduction+++GO:0002224///toll-like receptor signaling pathway+++GO:0034097///response to cytokine+++GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0000187///activation of MAPK activity+++GO:0044351///macropinocytosis+++GO:0000165///MAPK cascade+++GO:0016310///phosphorylation","mitogen-activated protein kinase-activated protein kinase 3","[MAPK3_HUMAN|Reviewed]RecName: Full=MAP kinase-activated protein kinase 3; Short=MAPK-activated protein kinase 3; Short=MAPKAP kinase 3; Short=MAPKAP-K3; Short=MAPKAPK-3; Short=MK-3; EC=2.7.11.1; AltName: Full=Chromosome 3p kinase; Short=3pK;+++[A0A024R2W7_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-activated protein kinase 3, isoform CRA_a {ECO:0000313|EMBL:EAW65132.1};+++[B5BUJ8_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-activated protein kinase 3 {ECO:0000313|EMBL:BAG70248.1}; Flags: Fragment;+++[C9J8E1_HUMAN|Unreviewed]SubName: Full=MAP kinase-activated protein kinase 3 {ECO:0000313|Ensembl:ENSP00000410970}; Flags: Fragment;+++[C9JPW3_HUMAN|Unreviewed]SubName: Full=MAP kinase-activated protein kinase 3 {ECO:0000313|Ensembl:ENSP00000402045}; Flags: Fragment;+++[H7C0G6_HUMAN|Unreviewed]SubName: Full=MAP kinase-activated protein kinase 3 {ECO:0000313|Ensembl:ENSP00000394894}; Flags: Fragment;"]
[790,"'CAD'",1380,1158,1233,1257,"01100///Metabolic pathways+++00240///Pyrimidine metabolism+++00250///Alanine, aspartate and glutamate metabolism","H00118///Congenital disorders of glycosylation (CDG) type I","M00051///Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP","R10949///Ammonia + Carboxyphosphate <=> Carbamate + Orthophosphate+++R10948///ATP:HCO3- phosphotransferase   ATP + HCO3- <=> ADP + Carboxyphosphate+++R01993///(S)-dihydroorotate amidohydrolase   (S)-Dihydroorotate + H2O <=> N-Carbamoyl-L-aspartate+++R01397///carbamoyl-phosphate:L-aspartate carbamoyltransferase   Carbamoyl phosphate + L-Aspartate <=> Orthophosphate + N-Carbamoyl-L-aspartate+++R01395///ATP:carbamate phosphotransferase   ATP + Carbamate <=> ADP + Carbamoyl phosphate+++R00575///HCO3-:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)   2 ATP + L-Glutamine + HCO3- + H2O <=> 2 ADP + Orthophosphate + L-Glutamate + Carbamoyl phosphate+++R00256///L-glutamine amidohydrolase   L-Glutamine + H2O <=> L-Glutamate + Ammonia","GO:0005654///nucleoplasm+++GO:0043195///terminal bouton+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0016363///nuclear matrix+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0004087///carbamoyl-phosphate synthase (ammonia) activity+++GO:0004151///dihydroorotase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0004672///protein kinase activity+++GO:0004070///aspartate carbamoyltransferase activity+++GO:0070335///aspartate binding+++GO:0042802///identical protein binding+++GO:0019899///enzyme binding+++GO:0004088///carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity","GO:0006526///arginine biosynthetic process+++GO:0014075///response to amine+++GO:0044205///'de novo' UMP biosynthetic process+++GO:0007565///female pregnancy+++GO:0017144///drug metabolic process+++GO:0006207///'de novo' pyrimidine nucleobase biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0046777///protein autophosphorylation+++GO:0006228///UTP biosynthetic process+++GO:0007507///heart development+++GO:0032868///response to insulin+++GO:0000050///urea cycle+++GO:0031100///animal organ regeneration+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0051414///response to cortisol+++GO:0019240///citrulline biosynthetic process+++GO:0035690///cellular response to drug+++GO:0007595///lactation+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0046134///pyrimidine nucleoside biosynthetic process+++GO:0042594///response to starvation+++GO:0001889///liver development+++GO:0031000///response to caffeine+++GO:0033574///response to testosterone","carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase","[PYR1_HUMAN|Reviewed]RecName: Full=CAD protein; Includes: RecName: Full=Glutamine-dependent carbamoyl-phosphate synthase; EC=6.3.5.5 {ECO:0000269|PubMed:24332717}; Includes: RecName: Full=Aspartate carbamoyltransferase; EC=2.1.3.2 {ECO:0000269|PubMed:24332717}; Includes: RecName: Full=Dihydroorotase; EC=3.5.2.3 {ECO:0000269|PubMed:24332717};+++[F8VPD4_HUMAN|Unreviewed]SubName: Full=CAD protein {ECO:0000313|Ensembl:ENSP00000384510};"]
[79012,"'CAMKV'",6,9,9,8,{"$nulls":4},"GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle","GO:0005516///calmodulin binding+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0099159///regulation of modification of postsynaptic structure","CaM kinase like vesicle associated","[CAMKV_HUMAN|Reviewed]RecName: Full=CaM kinase-like vesicle-associated protein;+++[A0A024R2U2_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated, isoform CRA_d {ECO:0000313|EMBL:EAW65032.1};+++[A0A024R331_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated, isoform CRA_c {ECO:0000313|EMBL:EAW65034.1};+++[A0A140VKD5_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 52e {ECO:0000313|EMBL:AEE61272.1};+++[B4DM24_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated protein {ECO:0000313|Ensembl:ENSP00000420053}; SubName: Full=cDNA FLJ54113, highly similar to Homo sapiens CaM kinase-like vesicle-associated (CAMKV), mRNA {ECO:0000313|EMBL:BAG59736.1};+++[B4DSW8_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated protein {ECO:0000313|Ensembl:ENSP00000420766}; SubName: Full=cDNA FLJ53649, highly similar to Mus musculus CaM kinase-like vesicle-associated (Camkv), mRNA {ECO:0000313|EMBL:BAG61780.1};+++[C9J9E2_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated protein {ECO:0000313|Ensembl:ENSP00000417614};+++[C9JSB2_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated protein {ECO:0000313|Ensembl:ENSP00000420000}; Flags: Fragment;+++[E7ETR1_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated protein {ECO:0000313|Ensembl:ENSP00000420724};+++[F8WDJ4_HUMAN|Unreviewed]SubName: Full=CaM kinase-like vesicle-associated protein {ECO:0000313|Ensembl:ENSP00000420139};+++[L8E961_HUMAN|Unreviewed]SubName: Full=Alternative protein CAMKV {ECO:0000313|EMBL:CCQ43709.1};"]
[79042,"'TSEN34'",881,1102,1041,1008,null,"H00897///Pontocerebellar hypoplasia",null,null,"GO:0005730///nucleolus+++GO:0000214///tRNA-intron endonuclease complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000213///tRNA-intron endonuclease activity+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity+++GO:0016829///lyase activity+++GO:0004519///endonuclease activity","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0008033///tRNA processing+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0006397///mRNA processing+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000379///tRNA-type intron splice site recognition and cleavage","tRNA splicing endonuclease subunit 34","[SEN34_HUMAN|Reviewed]RecName: Full=tRNA-splicing endonuclease subunit Sen34; EC=4.6.1.16; AltName: Full=Leukocyte receptor cluster member 5; AltName: Full=tRNA-intron endonuclease Sen34; Short=HsSen34;+++[A0A024R4N9_HUMAN|Unreviewed]RecName: Full=tRNA-splicing endonuclease subunit Sen34 {ECO:0000256|PIRNR:PIRNR017250}; EC=4.6.1.16 {ECO:0000256|PIRNR:PIRNR017250};+++[A0A0G2JNK5_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen34 {ECO:0000313|Ensembl:ENSP00000481573}; Flags: Fragment;+++[A9C4B9_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen34 {ECO:0000313|Ensembl:ENSP00000408689}; Flags: Fragment;+++[B0V3J0_HUMAN|Unreviewed]SubName: Full=tRNA-splicing endonuclease subunit Sen34 {ECO:0000313|Ensembl:ENSP00000400743}; Flags: Fragment;+++[B4DT51_HUMAN|Unreviewed]RecName: Full=tRNA-splicing endonuclease subunit Sen34 {ECO:0000256|PIRNR:PIRNR017250}; EC=4.6.1.16 {ECO:0000256|PIRNR:PIRNR017250};+++[E7EQB3_HUMAN|Unreviewed]RecName: Full=tRNA-splicing endonuclease subunit Sen34 {ECO:0000256|PIRNR:PIRNR017250}; EC=4.6.1.16 {ECO:0000256|PIRNR:PIRNR017250};"]
[79065,"'ATG9A'",1788,1848,1702,1779.33333333333,"04136///Autophagy - other+++04137///Mitophagy - animal+++04138///Autophagy - yeast+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000421///autophagosome membrane+++GO:0005783///endoplasmic reticulum+++GO:0031902///late endosome membrane+++GO:0005776///autophagosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005789///endoplasmic reticulum membrane+++GO:0055037///recycling endosome+++GO:0000407///phagophore assembly site+++GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005768///endosome","GO:0005515///protein binding","GO:0015031///protein transport+++GO:0044805///late nucleophagy+++GO:0034497///protein localization to phagophore assembly site+++GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy","autophagy related 9A","[ATG9A_HUMAN|Reviewed]RecName: Full=Autophagy-related protein 9A; AltName: Full=APG9-like 1; AltName: Full=mATG9;+++[A0A024R438_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 9 {ECO:0000256|RuleBase:RU364027};+++[C9IYZ9_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000406785}; Flags: Fragment;+++[C9JD65_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 9 {ECO:0000256|RuleBase:RU364027}; Flags: Fragment;+++[C9JDK4_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000404750}; Flags: Fragment;+++[C9JFV2_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000416435}; Flags: Fragment;+++[C9JKV7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000409164}; Flags: Fragment;+++[C9JS65_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000394345}; Flags: Fragment;+++[C9JX27_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000413569}; Flags: Fragment;+++[C9JXG2_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000401530}; Flags: Fragment;+++[F2Z3I6_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000390704};+++[H7C1G6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 9 {ECO:0000256|RuleBase:RU364027}; Flags: Fragment;"]
[79074,"'C2orf49'",231,197,183,203.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0072669///tRNA-splicing ligase complex","GO:0003674///molecular_function","GO:0048598///embryonic morphogenesis+++GO:0008150///biological_process","chromosome 2 open reading frame 49","[ASHWN_HUMAN|Reviewed]RecName: Full=Ashwin;+++[C9J4K0_HUMAN|Unreviewed]SubName: Full=Ashwin {ECO:0000313|Ensembl:ENSP00000386361};"]
[79133,"'NDUFAF5'",69,41,63,57.6666666666667,"04714///Thermogenesis","H00473///Mitochondrial complex I deficiency",null,null,"GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0008168///methyltransferase activity+++GO:0016740///transferase activity","GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0055114///oxidation-reduction process+++GO:0032259///methylation+++GO:0030961///peptidyl-arginine hydroxylation","NADH:ubiquinone oxidoreductase complex assembly factor 5","[NDUF5_HUMAN|Reviewed]RecName: Full=Arginine-hydroxylase NDUFAF5, mitochondrial {ECO:0000305}; EC=1.-.-.- {ECO:0000305|PubMed:27226634}; AltName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 {ECO:0000312|HGNC:HGNC:15899}; AltName: Full=Putative methyltransferase NDUFAF5; EC=2.1.1.- {ECO:0000305}; Flags: Precursor;+++[B3KR61_HUMAN|Unreviewed]SubName: Full=Arginine-hydroxylase NDUFAF5, mitochondrial {ECO:0000313|Ensembl:ENSP00000437325}; SubName: Full=HCG1811060, isoform CRA_c {ECO:0000313|EMBL:EAX10310.1}; SubName: Full=cDNA FLJ33741 fis, clone BRAWH2018875, weakly similar to Protein At1g22800 {ECO:0000313|EMBL:BAG52273.1};"]
[79144,"'PPDPF'",15553,19561,19304,18139.3333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":5},"GO:0030154///cell differentiation+++GO:0007275///multicellular organism development","pancreatic progenitor cell differentiation and proliferation factor","[PPDPF_HUMAN|Reviewed]RecName: Full=Pancreatic progenitor cell differentiation and proliferation factor; AltName: Full=Exocrine differentiation and proliferation factor;+++[X6R7I6_HUMAN|Unreviewed]SubName: Full=Pancreatic progenitor cell differentiation and proliferation factor {ECO:0000313|Ensembl:ENSP00000359196};"]
[79175,"'ZNF343'",105,101,103,103,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 343","[ZN343_HUMAN|Reviewed]RecName: Full=Zinc finger protein 343;+++[A0A087WZQ2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 343 {ECO:0000313|Ensembl:ENSP00000482819};+++[A0A0A0MSR0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 343 {ECO:0000313|Ensembl:ENSP00000399682}; Flags: Fragment;+++[A0A0A0MT63_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 343 {ECO:0000313|Ensembl:ENSP00000416488}; Flags: Fragment;"]
[79228,"'THOC6'",235,236,232,234.333333333333,"03013///RNA transport",null,"M00406///TREX complex+++M00405///THC complex",null,"GO:0000445///THO complex part of transcription export complex+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0000346///transcription export complex+++GO:0005654///nucleoplasm+++GO:0000347///THO complex+++GO:0016607///nuclear speck","GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0031124///mRNA 3'-end processing+++GO:0006405///RNA export from nucleus+++GO:0007275///multicellular organism development+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0007417///central nervous system development+++GO:0043066///negative regulation of apoptotic process+++GO:0006406///mRNA export from nucleus+++GO:0051028///mRNA transport+++GO:0006915///apoptotic process+++GO:0008380///RNA splicing","THO complex 6","[THOC6_HUMAN|Reviewed]RecName: Full=THO complex subunit 6 homolog; AltName: Full=Functional spliceosome-associated protein 35; Short=fSAP35; AltName: Full=WD repeat-containing protein 58;"]
[79369,"'B3GNT4'",31,27,45,34.3333333333333,"01100///Metabolic pathways+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,null,"R05975///UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + nLc5Cer+++R04659///UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase   UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide","GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity","GO:0030311///poly-N-acetyllactosamine biosynthetic process+++GO:0016266///O-glycan processing+++GO:0018146///keratan sulfate biosynthetic process+++GO:0006486///protein glycosylation","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4","[B3GN4_HUMAN|Reviewed]RecName: Full=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4; EC=2.4.1.149 {ECO:0000269|PubMed:11042166}; AltName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4; Short=BGnT-4; Short=Beta-1,3-Gn-T4; Short=Beta-1,3-N-acetylglucosaminyltransferase 4; Short=Beta3Gn-T4;+++[A0A024RBT1_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[A0A2R8YCM2_HUMAN|Unreviewed]SubName: Full=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 {ECO:0000313|Ensembl:ENSP00000493771};"]
[79568,"'MAIP1'",80,65,75,73.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix","GO:0043022///ribosome binding+++GO:0005515///protein binding","GO:0007007///inner mitochondrial membrane organization+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0036444///calcium import into the mitochondrion+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051204///protein insertion into mitochondrial membrane+++GO:0032979///protein insertion into mitochondrial inner membrane from matrix side","matrix AAA peptidase interacting protein 1","[MAIP1_HUMAN|Reviewed]RecName: Full=m-AAA protease-interacting protein 1, mitochondrial {ECO:0000303|PubMed:27642048}; AltName: Full=Matrix AAA peptidase-interacting protein 1 {ECO:0000312|HGNC:HGNC:26198}; Flags: Precursor;+++[A0A024R3U8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW70196.1};+++[H7C0V0_HUMAN|Unreviewed]SubName: Full=m-AAA protease-interacting protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000396846}; Flags: Fragment;"]
[79585,"'CORO7'",548.99,607,545,566.996666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0000139///Golgi membrane","GO:0003779///actin binding+++GO:0005515///protein binding","GO:0030041///actin filament polymerization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","coronin 7","[CORO7_HUMAN|Reviewed]RecName: Full=Coronin-7; Short=Crn7; AltName: Full=70 kDa WD repeat tumor rejection antigen homolog;+++[E7EP81_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000461187};+++[I3L0X8_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000458411}; Flags: Fragment;+++[I3L0Z7_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000458459};+++[I3L1G9_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};+++[I3L1M1_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818}; Flags: Fragment;+++[I3L1T5_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000459085}; Flags: Fragment;+++[I3L1Z1_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000459228};+++[I3L212_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000459286}; Flags: Fragment;+++[I3L258_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000459401}; Flags: Fragment;+++[I3L2S7_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000459888}; Flags: Fragment;+++[I3L2Y6_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818}; Flags: Fragment;+++[I3L351_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000460177}; Flags: Fragment;+++[I3L359_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000460199};+++[I3L423_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000460901}; Flags: Fragment;+++[I3L426_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818}; Flags: Fragment;+++[I3L442_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000460956}; Flags: Fragment;+++[I3L482_HUMAN|Unreviewed]SubName: Full=Coronin-7 {ECO:0000313|Ensembl:ENSP00000461051};+++[I3NI06_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818}; Flags: Fragment;"]
[79616,"'CCNJL'",181,163,166,170,"04140///Autophagy - animal+++03320///PPAR signaling pathway+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0004672///protein kinase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity","GO:0006468///protein phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division+++GO:0045787///positive regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation","cyclin J like","[CCNJL_HUMAN|Reviewed]RecName: Full=Cyclin-J-like protein;+++[A0A2R8Y754_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000496026};+++[A0A2R8Y7P8_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000496436};+++[A0A2R8YFU1_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000496735};+++[B4DZA8_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000257536}; SubName: Full=cDNA FLJ60987, weakly similar to Mus musculus cyclin J (Ccnj), mRNA {ECO:0000313|EMBL:BAG64020.1};+++[E5RFJ6_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000428836}; Flags: Fragment;+++[E7EN43_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000427960};+++[F6RF56_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000446367};"]
[79633,"'FAT4'",239,177,198,204.666666666667,"04392///Hippo signaling pathway - multiple species+++04391///Hippo signaling pathway - fly","H01393///Van Maldergem syndrome (VMLDS/VMS)",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell","GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:0021987///cerebral cortex development+++GO:0001822///kidney development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0007155///cell adhesion+++GO:0043931///ossification involved in bone maturation+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0035329///hippo signaling+++GO:0007009///plasma membrane organization+++GO:0072006///nephron development+++GO:0022008///neurogenesis+++GO:0003007///heart morphogenesis+++GO:0007219///Notch signaling pathway+++GO:0048565///digestive tract development+++GO:0072137///condensed mesenchymal cell proliferation+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation","FAT atypical cadherin 4","[FAT4_HUMAN|Reviewed]RecName: Full=Protocadherin Fat 4; Short=hFat4; AltName: Full=Cadherin family member 14; AltName: Full=FAT tumor suppressor homolog 4; AltName: Full=Fat-like cadherin protein FAT-J; Flags: Precursor;+++[B3KU84_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39327 fis, clone OCBBF2015506, highly similar to Mus musculus FAT tumor suppressor homolog 4 (Drosophila) (Fat4), mRNA {ECO:0000313|EMBL:BAG53346.1};+++[X2G0E6_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13819.1}; Flags: Fragment;+++[X2G0F0_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13824.1}; Flags: Fragment;+++[X2G248_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13820.1}; Flags: Fragment;+++[X2G254_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13825.1}; Flags: Fragment;+++[X2G5I7_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13823.1}; Flags: Fragment;+++[X2G756_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13822.1}; Flags: Fragment;+++[X2GA64_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13821.1}; Flags: Fragment;+++[X2GA70_HUMAN|Unreviewed]SubName: Full=Protocadherin FAT4 {ECO:0000313|EMBL:AHN13826.1}; Flags: Fragment;"]
[79656,"'BEND5'",55,63,47,55,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0045892///negative regulation of transcription, DNA-templated","BEN domain containing 5","[BEND5_HUMAN|Reviewed]RecName: Full=BEN domain-containing protein 5;+++[A0A0S2Z5N0_HUMAN|Unreviewed]SubName: Full=BEN domain containing 5 isoform 1 {ECO:0000313|EMBL:ALQ34234.1}; SubName: Full=Chromosome 1 open reading frame 165, isoform CRA_d {ECO:0000313|EMBL:EAX06852.1}; Flags: Fragment;+++[A0A0S2Z5T3_HUMAN|Unreviewed]SubName: Full=BEN domain containing 5 isoform 2 {ECO:0000313|EMBL:ALQ34235.1};+++[A0A0S2Z6J9_HUMAN|Unreviewed]SubName: Full=BEN domain containing 5 isoform 4 {ECO:0000313|EMBL:ALQ34236.1};"]
[79672,"'FN3KRP'",180,183,165,176,{"$nulls":4},"GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0043687///post-translational protein modification+++GO:0016310///phosphorylation","fructosamine 3 kinase related protein","[KT3K_HUMAN|Reviewed]RecName: Full=Ketosamine-3-kinase; EC=2.7.1.-; AltName: Full=Fructosamine-3-kinase-related protein; Short=FN3K-RP; Short=FN3K-related protein;+++[A0A140VK84_HUMAN|Unreviewed]SubName: Full=Fructosamine-3-kinase-related protein, isoform CRA_a {ECO:0000313|EMBL:EAW89817.1}; SubName: Full=Testis secretory sperm-binding protein Li 211a {ECO:0000313|EMBL:AEE61221.1};+++[I3L139_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000458550};+++[I3L2G3_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000459653}; Flags: Fragment;+++[I3L2K8_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000459751}; Flags: Fragment;+++[I3L378_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000460243}; Flags: Fragment;+++[I3L3W5_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000460777}; Flags: Fragment;+++[I3L407_HUMAN|Unreviewed]SubName: Full=Ketosamine-3-kinase {ECO:0000313|Ensembl:ENSP00000460869};+++[Q6FIG5_HUMAN|Unreviewed]SubName: Full=FN3KRP protein {ECO:0000313|EMBL:CAG38492.1};"]
[79695,"'GALNT12'",211,202,229,214,"00512///Mucin type O-glycan biosynthesis+++01100///Metabolic pathways","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane","GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity","GO:0016266///O-glycan processing+++GO:0006486///protein glycosylation","polypeptide N-acetylgalactosaminyltransferase 12","[GLT12_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 12; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 12; Short=GalNAc-T12; Short=pp-GaNTase 12; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 12; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12;+++[A0A087WT76_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 12 {ECO:0000313|Ensembl:ENSP00000477657}; Flags: Fragment;+++[L8EB63_HUMAN|Unreviewed]SubName: Full=Alternative protein GALNT12 {ECO:0000313|EMBL:CCQ43718.1};+++[Q68VJ1_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 12 {ECO:0000313|EMBL:CAD44541.1}; Flags: Fragment;"]
[79713,"'IGFLR1'",19,23,31,24.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding",null,"IGF like family receptor 1","[IGFR1_HUMAN|Reviewed]RecName: Full=IGF-like family receptor 1; AltName: Full=Transmembrane protein 149; AltName: Full=U2 small nuclear RNA auxiliary factor 1-like 4; Flags: Precursor;+++[K7EL86_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000465962};+++[K7EQI5_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000467842}; Flags: Fragment;+++[K7ES44_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000468545};+++[K7ESC2_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000468644}; Flags: Fragment;+++[S4R3Z9_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000474913}; Flags: Fragment;+++[U3KQL9_HUMAN|Unreviewed]SubName: Full=IGF-like family receptor 1 {ECO:0000313|Ensembl:ENSP00000476009}; Flags: Fragment;"]
[79735,"'TBC1D17'",1647,1851,1793,1763.66666666667,"04137///Mitophagy - animal",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0055037///recycling endosome+++GO:0005829///cytosol+++GO:0005776///autophagosome","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0006914///autophagy+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0090630///activation of GTPase activity+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:1902017///regulation of cilium assembly","TBC1 domain family member 17","[TBC17_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 17;+++[A0A087WXG5_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 17 {ECO:0000313|Ensembl:ENSP00000481003};+++[M0QXA2_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 17 {ECO:0000313|Ensembl:ENSP00000469010};+++[M0QYC9_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 17 {ECO:0000313|Ensembl:ENSP00000469747}; Flags: Fragment;+++[M0R2L2_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 17 {ECO:0000313|Ensembl:ENSP00000472647}; Flags: Fragment;"]
[79736,"'TEFM'",44,44,64,50.6666666666667,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:1990904///ribonucleoprotein complex+++GO:0042645///mitochondrial nucleoid","GO:0005515///protein binding+++GO:0030337///DNA polymerase processivity factor activity+++GO:0003723///RNA binding+++GO:0008821///crossover junction endodeoxyribonuclease activity","GO:0006259///DNA metabolic process+++GO:0006119///oxidative phosphorylation+++GO:0006264///mitochondrial DNA replication+++GO:0006392///transcription elongation from mitochondrial promoter+++GO:0006390///mitochondrial transcription","transcription elongation factor, mitochondrial","[TEFM_HUMAN|Reviewed]RecName: Full=Transcription elongation factor, mitochondrial; Flags: Precursor;+++[J3KTG7_HUMAN|Unreviewed]SubName: Full=Transcription elongation factor, mitochondrial {ECO:0000313|Ensembl:ENSP00000462973};"]
[79755,"'ZNF750'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008544///epidermis development+++GO:0030154///cell differentiation","zinc finger protein 750","[ZN750_HUMAN|Reviewed]RecName: Full=Zinc finger protein 750;+++[I3L0W7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 750 {ECO:0000313|Ensembl:ENSP00000458389};"]
[79781,"'IQCA1'",737,738,737,737.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0031514///motile cilium+++GO:0005856///cytoskeleton","GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination","IQ motif containing with AAA domain 1","[DRC11_HUMAN|Reviewed]RecName: Full=Dynein regulatory complex protein 11 {ECO:0000250|UniProtKB:A8IHT2}; AltName: Full=IQ and AAA domain-containing protein 1;+++[A0A0A0MSY6_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex protein 11 {ECO:0000313|Ensembl:ENSP00000407213};+++[B4DIF4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58100, highly similar to Homo sapiens IQ motif containing with AAA domain (IQCA), mRNA {ECO:0000313|EMBL:BAG58466.1}; Flags: Fragment;+++[H7BZR5_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex protein 11 {ECO:0000313|Ensembl:ENSP00000390964}; Flags: Fragment;"]
[79801,"'SHCBP1'",2,0,2,1.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005819///spindle","GO:0042169///SH2 domain binding+++GO:0005515///protein binding","GO:2000177///regulation of neural precursor cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway","SHC binding and spindle associated 1","[SHCBP_HUMAN|Reviewed]RecName: Full=SHC SH2 domain-binding protein 1;+++[A0A024R6R1_HUMAN|Unreviewed]SubName: Full=SHC SH2-domain binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW82681.1};+++[I3L3Z1_HUMAN|Unreviewed]SubName: Full=SHC SH2 domain-binding protein 1 {ECO:0000313|Ensembl:ENSP00000460840}; Flags: Fragment;"]
[79823,"'CAMKMT'",125,120,125.97,123.656666666667,"00310///Lysine degradation",null,null,"R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine","GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0032991///protein-containing complex+++GO:0005829///cytosol","GO:0008168///methyltransferase activity+++GO:0031072///heat shock protein binding+++GO:0018025///calmodulin-lysine N-methyltransferase activity+++GO:0016740///transferase activity","GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0006479///protein methylation+++GO:0018022///peptidyl-lysine methylation+++GO:0007005///mitochondrion organization+++GO:0032259///methylation","calmodulin-lysine N-methyltransferase","[CMKMT_HUMAN|Reviewed]RecName: Full=Calmodulin-lysine N-methyltransferase; Short=CLNMT; Short=CaM KMT; EC=2.1.1.60;+++[A0A0C4DGY0_HUMAN|Unreviewed]SubName: Full=Calmodulin-lysine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000482360};+++[B5MC16_HUMAN|Unreviewed]SubName: Full=Calmodulin-lysine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000385587};+++[B5MC79_HUMAN|Unreviewed]SubName: Full=Calmodulin-lysine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000384039};+++[D6W5A4_HUMAN|Unreviewed]SubName: Full=Chromosome 2 open reading frame 34, isoform CRA_a {ECO:0000313|EMBL:EAX00274.1};+++[H7C2N4_HUMAN|Unreviewed]SubName: Full=Calmodulin-lysine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000406936}; Flags: Fragment;+++[H7C2T0_HUMAN|Unreviewed]SubName: Full=Calmodulin-lysine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000407594}; Flags: Fragment;+++[H7C3B0_HUMAN|Unreviewed]SubName: Full=Calmodulin-lysine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000410783}; Flags: Fragment;"]
[79840,"'NHEJ1'",60,64,67,63.6666666666667,"03450///Non-homologous end-joining","H00924///Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation",null,null,"GO:0032807///DNA ligase IV complex+++GO:0070419///nonhomologous end joining complex+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0045027///DNA end binding","GO:0010212///response to ionizing radiation+++GO:0006302///double-strand break repair+++GO:0007417///central nervous system development+++GO:0030183///B cell differentiation+++GO:0051351///positive regulation of ligase activity+++GO:0030217///T cell differentiation+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair","non-homologous end joining factor 1","[NHEJ1_HUMAN|Reviewed]RecName: Full=Non-homologous end-joining factor 1; AltName: Full=Protein cernunnos; AltName: Full=XRCC4-like factor;+++[C9JWV4_HUMAN|Unreviewed]SubName: Full=Non-homologous end-joining factor 1 {ECO:0000313|Ensembl:ENSP00000407201}; Flags: Fragment;+++[F8WEB8_HUMAN|Unreviewed]SubName: Full=Non-homologous end-joining factor 1 {ECO:0000313|Ensembl:ENSP00000408421};+++[G5E9Q8_HUMAN|Unreviewed]SubName: Full=HCG2043685, isoform CRA_b {ECO:0000313|EMBL:EAW70679.1}; SubName: Full=Non-homologous end-joining factor 1 {ECO:0000313|Ensembl:ENSP00000408966};+++[H7C0G7_HUMAN|Unreviewed]SubName: Full=Non-homologous end-joining factor 1 {ECO:0000313|Ensembl:ENSP00000394896}; Flags: Fragment;"]
[79868,"'ALG13'",385,283,403,357,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis","H00118///Congenital disorders of glycosylation (CDG) type I+++H00606///Early infantile epileptic encephalopathy","M00055///N-glycan precursor biosynthesis","R05970///UDP-N-acetyl-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Chitobiosyldiphosphodolichol","GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0003723///RNA binding+++GO:0004577///N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity+++GO:0008233///peptidase activity","GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006508///proteolysis+++GO:0008152///metabolic process","ALG13, UDP-N-acetylglucosaminyltransferase subunit","[ALG13_HUMAN|Reviewed]RecName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; EC=2.4.1.141; EC=3.4.19.12; AltName: Full=Asparagine-linked glycosylation 13 homolog; AltName: Full=Glycosyltransferase 28 domain-containing protein 1; AltName: Full=UDP-N-acetylglucosamine transferase subunit ALG13 homolog;+++[A0A087WT15_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000477513};+++[A0A087WTT9_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000478130};+++[A0A087WVG5_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000479424};+++[A0A087WX01_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000480638};+++[A0A087WX43_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000480711};+++[A0A096LNJ4_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485067};+++[A0A096LNJ5_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485071}; Flags: Fragment;+++[A0A096LNL2_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485093};+++[A0A096LP10_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485333}; Flags: Fragment;+++[A0A096LP54_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485400}; Flags: Fragment;+++[A0A096LPI3_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485624}; Flags: Fragment;+++[A0A096LPK3_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485658}; Flags: Fragment;+++[A0A1B0GVW6_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000490681};+++[D6RE84_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000426892};"]
[79883,"'PODNL1'",2247,2660,2591,2499.33333333333,{"$nulls":4},"GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region","GO:0004860///protein kinase inhibitor activity","GO:0046426///negative regulation of JAK-STAT cascade+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006469///negative regulation of protein kinase activity","podocan like 1","[PONL1_HUMAN|Reviewed]RecName: Full=Podocan-like protein 1; Flags: Precursor;+++[A0A2U3TZJ2_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000345175};+++[B7Z3M0_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000254320}; SubName: Full=cDNA FLJ51218, weakly similar to Mus musculus podocan (Podn), mRNA {ECO:0000313|EMBL:BAH12256.1};+++[K7EJ07_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000464972}; Flags: Fragment;+++[K7EMV0_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000466659}; Flags: Fragment;+++[K7EPI2_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000467395};+++[K7EPR1_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000467495}; Flags: Fragment;+++[K7ER84_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000468151}; Flags: Fragment;+++[K7ERE6_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000468225}; Flags: Fragment;+++[K7ESB1_HUMAN|Unreviewed]SubName: Full=Podocan-like protein 1 {ECO:0000313|Ensembl:ENSP00000468630}; Flags: Fragment;"]
[79906,"'MORN1'",91,97,104,97.3333333333333,"04140///Autophagy - animal+++04146///Peroxisome+++04137///Mitophagy - animal","H00177///Adrenoleukodystrophy, neonatal (NALD)+++H00205///Peroxisome biogenesis disorder+++H01342///Zellweger syndrome (ZS)",{"$nulls":5},"MORN repeat containing 1","[MORN1_HUMAN|Reviewed]RecName: Full=MORN repeat-containing protein 1;+++[B4DRE3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60334, highly similar to MORN repeat-containing protein 1 {ECO:0000313|EMBL:BAG61255.1};+++[Q5T088_HUMAN|Unreviewed]SubName: Full=MORN repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000390261}; Flags: Fragment;+++[U3KQS9_HUMAN|Unreviewed]SubName: Full=MORN repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000476189}; Flags: Fragment;"]
[79924,"'ADM2'",179,227,127,177.666666666667,{"$nulls":4},"GO:0005576///extracellular region","GO:0005179///hormone activity+++GO:0044877///protein-containing complex binding","GO:0001525///angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0010628///positive regulation of gene expression+++GO:0006468///protein phosphorylation+++GO:0007586///digestion+++GO:0010469///regulation of signaling receptor activity+++GO:0045776///negative regulation of blood pressure+++GO:0007631///feeding behavior+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","adrenomedullin 2","[ADM2_HUMAN|Reviewed]RecName: Full=ADM2; AltName: Full=Intermedin; Contains: RecName: Full=Adrenomedullin-2; Short=AM2; AltName: Full=Intermedin-long; Short=IMDL; Contains: RecName: Full=Intermedin-short; Short=IMDS; Flags: Precursor;+++[Q6IC89_HUMAN|Unreviewed]SubName: Full=DJ579N16.4 protein {ECO:0000313|EMBL:CAG30365.1}; SubName: Full=HCG1653624, isoform CRA_a {ECO:0000313|EMBL:EAW73541.1};"]
[79947,"'DHDDS'",974,1035,959,989.333333333333,"01110///Biosynthesis of secondary metabolites+++00900///Terpenoid backbone biosynthesis","H00527///Retinitis pigmentosa (RP)",null,"R05556///(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10-55 isopentenyl units)   trans,trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> Dehydrodolichol diphosphate + n Diphosphate","GO:0043025///neuronal cell body+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:1904423///dehydrodolichyl diphosphate synthase complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0031985///Golgi cisterna+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm+++GO:0030496///midbody","GO:0005515///protein binding+++GO:0097110///scaffold protein binding+++GO:0017048///Rho GTPase binding+++GO:0045547///dehydrodolichyl diphosphate synthase activity+++GO:0000166///nucleotide binding+++GO:0017124///SH3 domain binding+++GO:0016301///kinase activity+++GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0030165///PDZ domain binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0002094///polyprenyltransferase activity","GO:0032467///positive regulation of cytokinesis+++GO:0006468///protein phosphorylation+++GO:0006489///dolichyl diphosphate biosynthetic process+++GO:0000281///mitotic cytokinesis+++GO:0051402///neuron apoptotic process+++GO:0006486///protein glycosylation+++GO:0051301///cell division+++GO:0030154///cell differentiation+++GO:0016310///phosphorylation+++GO:0006629///lipid metabolic process+++GO:0048699///generation of neurons+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0035556///intracellular signal transduction+++GO:0007049///cell cycle+++GO:0007030///Golgi organization+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0016094///polyprenol biosynthetic process","dehydrodolichyl diphosphate synthase subunit","[DHDDS_HUMAN|Reviewed]RecName: Full=Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000305}; EC=2.5.1.87 {ECO:0000269|PubMed:25066056, ECO:0000269|PubMed:28842490}; AltName: Full=Cis-isoprenyltransferase {ECO:0000303|PubMed:14652022}; Short=CIT {ECO:0000303|PubMed:28842490}; Short=Cis-IPTase {ECO:0000303|PubMed:14652022}; AltName: Full=Cis-prenyltransferase subunit hCIT {ECO:0000303|PubMed:28842490}; AltName: Full=Epididymis tissue protein Li 189m;+++[E9PI09_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018};+++[E9PI64_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018}; Flags: Fragment;+++[E9PKJ5_HUMAN|Unreviewed]SubName: Full=Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000313|Ensembl:ENSP00000433491}; Flags: Fragment;+++[E9PL99_HUMAN|Unreviewed]SubName: Full=Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000313|Ensembl:ENSP00000431407}; Flags: Fragment;+++[E9PR24_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018}; Flags: Fragment;+++[E9PRS7_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018}; Flags: Fragment;+++[E9PSH7_HUMAN|Unreviewed]SubName: Full=Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000313|Ensembl:ENSP00000433976}; Flags: Fragment;+++[F5H4K4_HUMAN|Unreviewed]SubName: Full=Citron Rho-interacting kinase {ECO:0000313|Ensembl:ENSP00000446105}; Flags: Fragment;+++[H0Y4T1_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018}; Flags: Fragment;+++[H0YGG8_HUMAN|Unreviewed]SubName: Full=Citron Rho-interacting kinase {ECO:0000313|Ensembl:ENSP00000443199}; Flags: Fragment;+++[H7BYJ3_HUMAN|Unreviewed]SubName: Full=Citron Rho-interacting kinase {ECO:0000313|Ensembl:ENSP00000376305}; Flags: Fragment;+++[Q5T0A0_HUMAN|Unreviewed]SubName: Full=Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000313|Ensembl:ENSP00000403529};+++[Q5T0A1_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018};+++[Q5T0A2_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018}; Flags: Fragment;+++[Q5T0A3_HUMAN|Unreviewed]RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018}; EC=2.5.1.- {ECO:0000256|RuleBase:RU363018}; Flags: Fragment;+++[Q5T0A6_HUMAN|Unreviewed]SubName: Full=Dehydrodolichyl diphosphate synthase complex subunit DHDDS {ECO:0000313|Ensembl:ENSP00000399781}; Flags: Fragment;"]
[79987,"'SVEP1'",99,73,85,85.6666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0003682///chromatin binding","GO:0007155///cell adhesion","sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1","[SVEP1_HUMAN|Reviewed]RecName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; AltName: Full=CCP module-containing protein 22; AltName: Full=Polydom; AltName: Full=Selectin-like osteoblast-derived protein; Short=SEL-OB; AltName: Full=Serologically defined breast cancer antigen NY-BR-38; Flags: Precursor;+++[A0A0A0MSD0_HUMAN|Unreviewed]SubName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000384917};+++[B3KQM1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90719 fis, clone PLACE1008744, highly similar to Mus musculus sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1, mRNA {ECO:0000313|EMBL:BAG52083.1};+++[L8EBF2_HUMAN|Unreviewed]SubName: Full=Alternative protein SVEP1 {ECO:0000313|EMBL:CCQ43878.1};+++[Q5JB40_HUMAN|Unreviewed]SubName: Full=Selectin-like protein {ECO:0000313|EMBL:AAQ89957.1};"]
[80000,"'GREB1L'",74,35,44,51,null,"H00572///ESCO2-related disorders",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0042802///identical protein binding+++GO:0016407///acetyltransferase activity+++GO:0061733///peptide-lysine-N-acetyltransferase activity+++GO:0008080///N-acetyltransferase activity+++GO:0008270///zinc ion binding","GO:0060562///epithelial tube morphogenesis+++GO:0072177///mesonephric duct development+++GO:0001822///kidney development+++GO:0001656///metanephros development+++GO:0061205///paramesonephric duct development+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0007275///multicellular organism development+++GO:0003231///cardiac ventricle development+++GO:0030539///male genitalia development+++GO:0060065///uterus development","GREB1 like retinoic acid receptor coactivator","[GRB1L_HUMAN|Reviewed]RecName: Full=GREB1-like protein; AltName: Full=Growth regulation by estrogen in breast cancer 1-like protein;+++[J3KRT4_HUMAN|Unreviewed]SubName: Full=GREB1-like protein {ECO:0000313|Ensembl:ENSP00000462152}; Flags: Fragment;+++[J3QQW0_HUMAN|Unreviewed]SubName: Full=GREB1-like protein {ECO:0000313|Ensembl:ENSP00000463926}; Flags: Fragment;+++[J3QR03_HUMAN|Unreviewed]SubName: Full=GREB1-like protein {ECO:0000313|Ensembl:ENSP00000463976}; Flags: Fragment;"]
[80034,"'CSRNP3'",119,74,77,90,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0043065///positive regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0010923///negative regulation of phosphatase activity+++GO:0006915///apoptotic process","cysteine and serine rich nuclear protein 3","[CSRN3_HUMAN|Reviewed]RecName: Full=Cysteine/serine-rich nuclear protein 3; Short=CSRNP-3; AltName: Full=Protein FAM130A2; AltName: Full=TGF-beta-induced apoptosis protein 2; Short=TAIP-2;+++[B8ZZD9_HUMAN|Unreviewed]SubName: Full=Cysteine/serine-rich nuclear protein 3 {ECO:0000313|Ensembl:ENSP00000386278}; Flags: Fragment;+++[E7EN18_HUMAN|Unreviewed]SubName: Full=Cysteine/serine-rich nuclear protein 3 {ECO:0000313|Ensembl:ENSP00000412081}; Flags: Fragment;+++[J3KQ49_HUMAN|Unreviewed]SubName: Full=Cysteine/serine-rich nuclear protein 3 {ECO:0000313|Ensembl:ENSP00000387195};"]
[80070,"'ADAMTS20'",54,23,33,36.6666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix","GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0046872///metal ion binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008270///zinc ion binding+++GO:0008237///metallopeptidase activity","GO:0048070///regulation of developmental pigmentation+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0006508///proteolysis+++GO:0043066///negative regulation of apoptotic process+++GO:0009967///positive regulation of signal transduction+++GO:0030198///extracellular matrix organization","ADAM metallopeptidase with thrombospondin type 1 motif 20","[ATS20_HUMAN|Reviewed]RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 20; Short=ADAM-TS 20; Short=ADAM-TS20; Short=ADAMTS-20; EC=3.4.24.-; Flags: Precursor;+++[E9PBD5_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 20 {ECO:0000313|Ensembl:ENSP00000378911};+++[G3V1X8_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 20 {ECO:0000313|Ensembl:ENSP00000448341}; SubName: Full=ADAM metallopeptidase with thrombospondin type 1 motif, 20, isoform CRA_c {ECO:0000313|EMBL:EAW57863.1};+++[H0YHN3_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 20 {ECO:0000313|Ensembl:ENSP00000447427}; Flags: Fragment;+++[L0R6C0_HUMAN|Unreviewed]SubName: Full=Alternative protein ADAMTS20 {ECO:0000313|EMBL:CCO13670.1};"]
[80145,"'THOC7'",339,283,299,307,"03013///RNA transport",null,"M00405///THC complex+++M00406///TREX complex",null,"GO:0000445///THO complex part of transcription export complex+++GO:0005654///nucleoplasm+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0000347///THO complex+++GO:0000346///transcription export complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006406///mRNA export from nucleus+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0051028///mRNA transport+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0006405///RNA export from nucleus","THO complex 7","[THOC7_HUMAN|Reviewed]RecName: Full=THO complex subunit 7 homolog; AltName: Full=Functional spliceosome-associated protein 24; Short=fSAP24; AltName: Full=Ngg1-interacting factor 3-like protein 1-binding protein 1; Short=NIF3L1-binding protein 1; AltName: Full=hTREX30;+++[A0A024R332_HUMAN|Unreviewed]SubName: Full=Ngg1 interacting factor 3 like 1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW65421.1};+++[A0A024R341_HUMAN|Unreviewed]SubName: Full=Ngg1 interacting factor 3 like 1 binding protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW65420.1}; SubName: Full=THO complex subunit 7 homolog {ECO:0000313|Ensembl:ENSP00000418518};+++[F8WF22_HUMAN|Unreviewed]SubName: Full=THO complex subunit 7 homolog {ECO:0000313|Ensembl:ENSP00000419443}; Flags: Fragment;+++[H7C5E3_HUMAN|Unreviewed]SubName: Full=THO complex subunit 7 homolog {ECO:0000313|Ensembl:ENSP00000419682}; Flags: Fragment;"]
[80155,"'NAA15'",552,471,505,509.333333333333,"04137///Mitophagy - animal+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04140///Autophagy - animal+++05012///Parkinson's disease+++05016///Huntington's disease+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++05010///Alzheimer's disease+++01100///Metabolic pathways+++00190///Oxidative phosphorylation","H00773///Autosomal dominant mental retardation","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005667///transcription factor complex+++GO:0031415///NatA complex","GO:0016407///acetyltransferase activity+++GO:0005515///protein binding+++GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0043022///ribosome binding+++GO:0003723///RNA binding","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001525///angiogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0050821///protein stabilization+++GO:0017196///N-terminal peptidyl-methionine acetylation+++GO:0030154///cell differentiation+++GO:0006474///N-terminal protein amino acid acetylation","N(alpha)-acetyltransferase 15, NatA auxiliary subunit","[NAA15_HUMAN|Reviewed]RecName: Full=N-alpha-acetyltransferase 15, NatA auxiliary subunit; AltName: Full=Gastric cancer antigen Ga19; AltName: Full=N-terminal acetyltransferase; AltName: Full=NMDA receptor-regulated protein 1; AltName: Full=Protein tubedown-1; AltName: Full=Tbdn100;+++[A0A0B4J1W3_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 15, NatA auxiliary subunit {ECO:0000313|Ensembl:ENSP00000381920};+++[B2RBE5_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95468, highly similar to Homo sapiens transcriptional coactivator tubedown-100 (TBDN100),transcript variant 1, mRNA {ECO:0000313|EMBL:BAG37192.1};+++[D6RAP7_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 15, NatA auxiliary subunit {ECO:0000313|Ensembl:ENSP00000421839};+++[Q58F05_HUMAN|Unreviewed]SubName: Full=NARG1 protein {ECO:0000313|EMBL:AAH32642.1}; Flags: Fragment;"]
[80183,"'RUBCNL'",21,21,31,24.3333333333333,{"$nulls":7},"RUN and cysteine rich domain containing beclin 1 interacting protein like","[RUBCL_HUMAN|Reviewed]RecName: Full=Protein RUBCNL-like {ECO:0000305};+++[A0A0A0MRV7_HUMAN|Unreviewed]SubName: Full=Protein RUBCNL-like {ECO:0000313|Ensembl:ENSP00000368074};+++[A8XR14_HUMAN|Unreviewed]SubName: Full=Protein RUBCNL-like {ECO:0000313|Ensembl:ENSP00000414579}; Flags: Fragment;+++[B7ZBN5_HUMAN|Unreviewed]SubName: Full=Protein RUBCNL-like {ECO:0000313|Ensembl:ENSP00000386578};+++[E7EMA2_HUMAN|Unreviewed]SubName: Full=Protein RUBCNL-like {ECO:0000313|Ensembl:ENSP00000412507};+++[Q5W050_HUMAN|Unreviewed]SubName: Full=Protein RUBCNL-like {ECO:0000313|Ensembl:ENSP00000402357}; Flags: Fragment;"]
[80218,"'NAA50'",1094,842,865,933.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0031415///NatA complex+++GO:0005829///cytosol","GO:0052858///peptidyl-lysine acetyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008080///N-acetyltransferase activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004596///peptide alpha-N-acetyltransferase activity","GO:0006474///N-terminal protein amino acid acetylation+++GO:0043967///histone H4 acetylation+++GO:0007064///mitotic sister chromatid cohesion+++GO:0071962///mitotic sister chromatid cohesion, centromeric+++GO:0034087///establishment of mitotic sister chromatid cohesion+++GO:0016573///histone acetylation","N(alpha)-acetyltransferase 50, NatE catalytic subunit","[NAA50_HUMAN|Reviewed]RecName: Full=N-alpha-acetyltransferase 50 {ECO:0000305}; Short=hNaa50p {ECO:0000303|PubMed:19744929, ECO:0000303|PubMed:22311970}; EC=2.3.1.258 {ECO:0000269|PubMed:19744929, ECO:0000269|PubMed:21900231, ECO:0000269|PubMed:22311970, ECO:0000269|PubMed:27484799}; AltName: Full=N-acetyltransferase 13; AltName: Full=N-acetyltransferase 5 {ECO:0000303|PubMed:16507339}; Short=hNAT5 {ECO:0000303|PubMed:16507339}; AltName: Full=N-acetyltransferase san homolog {ECO:0000303|PubMed:16507339}; Short=hSAN {ECO:0000303|PubMed:16507339}; AltName: Full=N-epsilon-acetyltransferase 50 {ECO:0000305}; EC=2.3.1.- {ECO:0000269|PubMed:19744929}; AltName: Full=NatE catalytic subunit;+++[A0A087WWJ2_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000480264};+++[A0A0D9SF32_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000486244};+++[B0AZT5_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000417488}; SubName: Full=cDNA FLJ51877, highly similar to Homo sapiens Mak3 homolog (MAK3), mRNA {ECO:0000313|EMBL:BAG59104.1}; SubName: Full=cDNA, FLJ79525, highly similar to Homo sapiens Mak3 homolog (MAK3), mRNA {ECO:0000313|EMBL:BAF98767.1};+++[C9J5D1_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000417110};+++[C9J5J3_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000418490};+++[C9JZU6_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000419729}; Flags: Fragment;+++[E7EQ69_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000417837};+++[F8WCK0_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 50 {ECO:0000313|Ensembl:ENSP00000418323};"]
[80233,"'FAAP100'",1010,1060,1048,1039.33333333333,"03460///Fanconi anemia pathway",null,"M00413///FA core complex",null,"GO:0005654///nucleoplasm+++GO:0045111///intermediate filament cytoskeleton+++GO:0043240///Fanconi anaemia nuclear complex+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0036297///interstrand cross-link repair+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus","FA core complex associated protein 100","[FP100_HUMAN|Reviewed]RecName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000303|PubMed:17396147, ECO:0000312|HGNC:HGNC:26171}; AltName: Full=Fanconi anemia-associated protein of 100 kDa;+++[A0A024R8W1_HUMAN|Unreviewed]SubName: Full=Chromosome 17 open reading frame 70, isoform CRA_a {ECO:0000313|EMBL:EAW89659.1};+++[A4ZI32_HUMAN|Unreviewed]SubName: Full=Fanconi anemia core complex 100 kDa subunit {ECO:0000313|EMBL:ABK88282.1};+++[E7EVV8_HUMAN|Unreviewed]SubName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000313|Ensembl:ENSP00000399674};+++[F5GZS4_HUMAN|Unreviewed]SubName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000313|Ensembl:ENSP00000444241}; Flags: Fragment;+++[F5H095_HUMAN|Unreviewed]SubName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000313|Ensembl:ENSP00000438149}; Flags: Fragment;+++[F5H5G6_HUMAN|Unreviewed]SubName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000313|Ensembl:ENSP00000443415}; Flags: Fragment;+++[I3L2L9_HUMAN|Unreviewed]SubName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000313|Ensembl:ENSP00000459776}; Flags: Fragment;+++[J3KQD8_HUMAN|Unreviewed]SubName: Full=Fanconi anemia core complex-associated protein 100 {ECO:0000313|Ensembl:ENSP00000395348};"]
[80298,"'MTERF2'",42,64,76,60.6666666666667,{"$nulls":4},"GO:0042645///mitochondrial nucleoid+++GO:0005739///mitochondrion","GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding","GO:0006393///termination of mitochondrial transcription+++GO:0006355///regulation of transcription, DNA-templated","mitochondrial transcription termination factor 2","[MTEF2_HUMAN|Reviewed]RecName: Full=Transcription termination factor 2, mitochondrial; AltName: Full=Mitochondrial transcription termination factor 2; Short=mTERF2; AltName: Full=Mitochondrial transcription termination factor-like protein; Short=mTERF-like; Short=mTERFL {ECO:0000303|PubMed:16226716}; AltName: Full=mTERF domain-containing protein 3, mitochondrial; Flags: Precursor;+++[A0A024RBL7_HUMAN|Unreviewed]SubName: Full=mTERF domain containing 3, isoform CRA_a {ECO:0000313|EMBL:EAW97794.1};+++[F8VSD8_HUMAN|Unreviewed]SubName: Full=Transcription termination factor 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000448343}; Flags: Fragment;+++[F8VSL4_HUMAN|Unreviewed]SubName: Full=Transcription termination factor 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000448246}; Flags: Fragment;+++[F8VXH5_HUMAN|Unreviewed]SubName: Full=Transcription termination factor 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000448854}; Flags: Fragment;"]
[80313,"'LRRC27'",265.48,220.12,235.95,240.516666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane",null,"GO:0007165///signal transduction","leucine rich repeat containing 27","[LRC27_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 27;+++[A0A140VJN2_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 108 {ECO:0000313|EMBL:AEE61019.1};+++[B3KUK5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40099 fis, clone TESTI2004431, highly similar to Leucine-rich repeat-containing protein 27 {ECO:0000313|EMBL:BAG53467.1};+++[B4DW88_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58633, highly similar to Leucine-rich repeat-containing protein 27 {ECO:0000313|EMBL:BAG62950.1};"]
[80339,"'PNPLA3'",505.83,416,665,528.943333333333,"01100///Metabolic pathways+++00561///Glycerolipid metabolism","H01333///Nonalcoholic fatty liver disease (NAFLD)","M00098///Acylglycerol degradation","R02250///triacylglycerol acylhydrolase   Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase   1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid","GO:0016020///membrane+++GO:0005811///lipid droplet+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0004465///lipoprotein lipase activity+++GO:0035727///lysophosphatidic acid binding+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004806///triglyceride lipase activity+++GO:0042171///lysophosphatidic acid acyltransferase activity+++GO:0016787///hydrolase activity+++GO:0004623///phospholipase A2 activity+++GO:0051265///diolein transacylation activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0051264///mono-olein transacylation activity+++GO:0016411///acylglycerol O-acyltransferase activity+++GO:0016740///transferase activity","GO:0036155///acylglycerol acyl-chain remodeling+++GO:0016042///lipid catabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0034389///lipid droplet organization+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0036153///triglyceride acyl-chain remodeling+++GO:0055088///lipid homeostasis+++GO:0006629///lipid metabolic process+++GO:0019433///triglyceride catabolic process","patatin like phospholipase domain containing 3","[PLPL3_HUMAN|Reviewed]RecName: Full=1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 {ECO:0000305|PubMed:22560221}; EC=2.3.1.51 {ECO:0000269|PubMed:22560221}; AltName: Full=Acylglycerol transacylase {ECO:0000303|PubMed:15364929}; AltName: Full=Adiponutrin {ECO:0000303|PubMed:22560221}; Short=ADPN {ECO:0000303|PubMed:22560221}; AltName: Full=Calcium-independent phospholipase A2-epsilon {ECO:0000303|PubMed:15364929}; Short=iPLA2-epsilon {ECO:0000303|PubMed:15364929}; AltName: Full=Lysophosphatidic acid acyltransferase {ECO:0000303|PubMed:22560221}; AltName: Full=Patatin-like phospholipase domain-containing protein 3 {ECO:0000303|PubMed:19224197}; EC=3.1.1.3 {ECO:0000269|PubMed:15364929, ECO:0000269|PubMed:20034933, ECO:0000269|PubMed:22560221};+++[F8W8E5_HUMAN|Unreviewed]SubName: Full=1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 {ECO:0000313|Ensembl:ENSP00000384668};+++[U3N4F2_HUMAN|Unreviewed]SubName: Full=Patatin-like phospholipase domain-containing protein 3 {ECO:0000313|EMBL:AGW25376.1}; Flags: Fragment;+++[U3N901_HUMAN|Unreviewed]SubName: Full=Patatin-like phospholipase domain-containing protein 3 {ECO:0000313|EMBL:AGW25377.1}; Flags: Fragment;"]
[8045,"'RASSF7'",833,883,723,813,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:0070507///regulation of microtubule cytoskeleton organization+++GO:0006915///apoptotic process+++GO:0007165///signal transduction","Ras association domain family member 7","[RASF7_HUMAN|Reviewed]RecName: Full=Ras association domain-containing protein 7; AltName: Full=HRAS1-related cluster protein 1;+++[A0A024RCE4_HUMAN|Unreviewed]SubName: Full=Ras association (RalGDS/AF-6) domain family 7, isoform CRA_a {ECO:0000313|EMBL:EAX02350.1};+++[A0A0G2JLR5_HUMAN|Unreviewed]SubName: Full=Ras association domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000477800};+++[A0A0G2JMW4_HUMAN|Unreviewed]SubName: Full=Ras association domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000480155};+++[A0A0J9YYE4_HUMAN|Unreviewed]SubName: Full=Ras association domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000488812};+++[E9PM39_HUMAN|Unreviewed]SubName: Full=Ras association domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000433165}; Flags: Fragment;+++[F8W7Q0_HUMAN|Unreviewed]SubName: Full=Ras association domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000413484};+++[H0YEI0_HUMAN|Unreviewed]SubName: Full=Ras association domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000435885}; Flags: Fragment;"]
[80731,"'THSD7B'",3,3,0,2,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0003697///single-stranded DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003727///single-stranded RNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition","thrombospondin type 1 domain containing 7B","[THS7B_HUMAN|Reviewed]RecName: Full=Thrombospondin type-1 domain-containing protein 7B; Flags: Precursor;+++[C9JKN6_HUMAN|Unreviewed]SubName: Full=Thrombospondin type-1 domain-containing protein 7B {ECO:0000313|Ensembl:ENSP00000413841};+++[E7EM75_HUMAN|Unreviewed]SubName: Full=Thrombospondin type-1 domain-containing protein 7B {ECO:0000313|Ensembl:ENSP00000387145};+++[Q8WUV0_HUMAN|Unreviewed]SubName: Full=THSD7B protein {ECO:0000313|EMBL:AAH19344.1}; Flags: Fragment;+++[R4GMU2_HUMAN|Unreviewed]SubName: Full=Thrombospondin type-1 domain-containing protein 7B {ECO:0000313|Ensembl:ENSP00000473349};"]
[80764,"'THAP7'",440,515,509,488,{"$nulls":4},"GO:0005694///chromosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031965///nuclear membrane+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0047485///protein N-terminus binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","THAP domain containing 7","[THAP7_HUMAN|Reviewed]RecName: Full=THAP domain-containing protein 7;"]
[8082,"'SSPN'",699,600,611,636.666666666667,{"$nulls":4},"GO:0045211///postsynaptic membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0030133///transport vesicle+++GO:0042383///sarcolemma+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0005887///integral component of plasma membrane",null,"GO:0007155///cell adhesion+++GO:0006936///muscle contraction","sarcospan","[SSPN_HUMAN|Reviewed]RecName: Full=Sarcospan; AltName: Full=K-ras oncogene-associated protein; AltName: Full=Kirsten-ras-associated protein;+++[A1YBP2_HUMAN|Unreviewed]SubName: Full=Nanospan {ECO:0000313|EMBL:ABI78937.1};+++[F5H0K2_HUMAN|Unreviewed]SubName: Full=Sarcospan {ECO:0000313|Ensembl:ENSP00000438801};+++[F5H381_HUMAN|Unreviewed]SubName: Full=Sarcospan {ECO:0000313|Ensembl:ENSP00000445360}; Flags: Fragment;"]
[80863,"'PRRT1'",2,8,0,3.33333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0099055///integral component of postsynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0016021///integral component of membrane",null,"GO:0009607///response to biotic stimulus","proline rich transmembrane protein 1","[PRRT1_HUMAN|Reviewed]RecName: Full=Proline-rich transmembrane protein 1; AltName: Full=Dispanin subfamily D member 1; Short=DSPD1;+++[A0A024RCX2_HUMAN|Unreviewed]SubName: Full=Proline-rich transmembrane protein 1, isoform CRA_a {ECO:0000313|EMBL:EAX03590.1}; Flags: Fragment;+++[A0A1U9X8D6_HUMAN|Unreviewed]SubName: Full=PRRT1 {ECO:0000313|EMBL:AQY77057.1};+++[A2ABC7_HUMAN|Unreviewed]SubName: Full=Proline-rich transmembrane protein 1 {ECO:0000313|Ensembl:ENSP00000389727}; Flags: Fragment;"]
[81031,"'SLC2A10'",626,569,642,612.333333333333,null,"H00919///Arterial tortuosity syndrome",null,null,"GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0005215///transporter activity+++GO:0055056///D-glucose transmembrane transporter activity+++GO:0005351///carbohydrate:proton symporter activity+++GO:0022857///transmembrane transporter activity","GO:0008645///hexose transmembrane transport+++GO:0008643///carbohydrate transport+++GO:1904659///glucose transmembrane transport+++GO:0055085///transmembrane transport+++GO:1902600///proton transmembrane transport","solute carrier family 2 member 10","[GTR10_HUMAN|Reviewed]RecName: Full=Solute carrier family 2, facilitated glucose transporter member 10; AltName: Full=Glucose transporter type 10; Short=GLUT-10;+++[A0A087WUH5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 10 {ECO:0000313|Ensembl:ENSP00000478679};+++[Q8TDC7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2 facilitated glucose transporter member 10 {ECO:0000313|EMBL:AAL87106.1}; Flags: Fragment;"]
[814,"'CAMK4'",7,11,6,8,"04925///Aldosterone synthesis and secretion+++04921///Oxytocin signaling pathway+++04211///Longevity regulating pathway+++05034///Alcoholism+++04380///Osteoclast differentiation+++04020///Calcium signaling pathway+++04722///Neurotrophin signaling pathway+++04371///Apelin signaling pathway+++05031///Amphetamine addiction+++04725///Cholinergic synapse+++04024///cAMP signaling pathway+++04720///Long-term potentiation",{"$nulls":3},"GO:0098978///glutamatergic synapse+++GO:0001650///fibrillar center+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0098794///postsynapse+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0005516///calmodulin binding+++GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0000166///nucleotide binding","GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0043011///myeloid dendritic cell differentiation+++GO:0016310///phosphorylation+++GO:0045670///regulation of osteoclast differentiation+++GO:0033081///regulation of T cell differentiation in thymus+++GO:0007616///long-term memory+++GO:0002372///myeloid dendritic cell cytokine production+++GO:0035556///intracellular signal transduction+++GO:0002250///adaptive immune response+++GO:0018105///peptidyl-serine phosphorylation","calcium/calmodulin dependent protein kinase IV","[KCC4_HUMAN|Reviewed]RecName: Full=Calcium/calmodulin-dependent protein kinase type IV; Short=CaMK IV; EC=2.7.11.17; AltName: Full=CaM kinase-GR;+++[D6RCD6_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase type IV {ECO:0000313|Ensembl:ENSP00000423761};+++[D6RE65_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase type IV {ECO:0000313|Ensembl:ENSP00000426940}; Flags: Fragment;+++[D6REY7_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase type IV {ECO:0000313|Ensembl:ENSP00000421606};"]
[81539,"'SLC38A1'",1272,921,778,990.333333333333,"04727///GABAergic synapse+++04724///Glutamatergic synapse",{"$nulls":3},"GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0030424///axon+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0015293///symporter activity+++GO:0016740///transferase activity+++GO:0005283///amino acid:sodium symporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0019809///spermidine binding+++GO:0008080///N-acetyltransferase activity+++GO:0004145///diamine N-acetyltransferase activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity+++GO:0004060///arylamine N-acetyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0016407///acetyltransferase activity","GO:0006865///amino acid transport+++GO:0009447///putrescine catabolic process+++GO:0006598///polyamine catabolic process+++GO:0032918///spermidine acetylation+++GO:0006596///polyamine biosynthetic process+++GO:0007565///female pregnancy+++GO:0001525///angiogenesis+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:0042127///regulation of cell proliferation+++GO:0001504///neurotransmitter uptake+++GO:0006595///polyamine metabolic process+++GO:0015804///neutral amino acid transport+++GO:0006811///ion transport+++GO:0006805///xenobiotic metabolic process+++GO:0006868///glutamine transport+++GO:0003333///amino acid transmembrane transport+++GO:0006814///sodium ion transport","solute carrier family 38 member 1","[S38A1_HUMAN|Reviewed]RecName: Full=Sodium-coupled neutral amino acid transporter 1; AltName: Full=Amino acid transporter A1; AltName: Full=N-system amino acid transporter 2; AltName: Full=Solute carrier family 38 member 1; AltName: Full=System A amino acid transporter 1; AltName: Full=System N amino acid transporter 1;+++[A0A024R124_HUMAN|Unreviewed]SubName: Full=Solute carrier family 38, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW57899.1};+++[A0A0S2A4Q6_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ALN12626.1};+++[A0A0S2A5J2_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ALN12932.1};+++[A0A0S2A5S1_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ALN13001.1};+++[A0A0S2A5X5_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ALN13040.1};+++[A4Z6T8_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01137.1};+++[A4Z6T9_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01138.1}; SubName: Full=N-acetyltransferase 2 (Arylamine N-acetyltransferase), isoform CRA_b {ECO:0000313|EMBL:EAW63786.1};+++[A4Z6U4_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01143.1};+++[A4Z6U6_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01145.1};+++[A4Z6U7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01146.1};+++[A4Z6U9_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01148.1};+++[A4Z6V9_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01158.1};+++[A4Z6Y1_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01180.1};+++[A4Z6Y3_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01182.1};+++[A4Z6Y5_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01184.1};+++[A4Z737_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01236.1};+++[A4Z787_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01286.1};+++[A4Z7F6_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01355.1};+++[A4Z7H3_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01372.1};+++[A4Z7J7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01396.1};+++[A4Z7K4_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01403.1};+++[A4Z7P9_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01448.1};+++[A4Z7V0_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01499.1};+++[A4Z867_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01616.1};+++[A6NJE6_HUMAN|Unreviewed]SubName: Full=Diamine acetyltransferase 1 {ECO:0000313|Ensembl:ENSP00000368553};+++[A6NM56_HUMAN|Unreviewed]SubName: Full=Diamine acetyltransferase 1 {ECO:0000313|Ensembl:ENSP00000368555};+++[A9X7Q9_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABK34571.1};+++[A9X7U6_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABK34608.1};+++[A9X7X6_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABK34638.1};+++[A9X816_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABK34678.1};+++[A9X844_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABK34706.1};+++[A9X854_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABK34716.1};+++[A9X868_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABK34730.1};+++[E7EWF9_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|Ensembl:ENSP00000428416};+++[E9PD37_HUMAN|Unreviewed]SubName: Full=Diamine acetyltransferase 1 {ECO:0000313|Ensembl:ENSP00000368556};+++[F8VX04_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 1 {ECO:0000313|Ensembl:ENSP00000449756};+++[F8VX12_HUMAN|Unreviewed]SubName: Full=Sodium-coupled neutral amino acid transporter 1 {ECO:0000313|Ensembl:ENSP00000449744}; Flags: Fragment;+++[Q400I5_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:CAE46174.1}; EC=2.3.1.5 {ECO:0000313|EMBL:CAE46174.1}; Flags: Fragment;+++[Q400I7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:CAE46172.1}; EC=2.3.1.5 {ECO:0000313|EMBL:CAE46172.1}; Flags: Fragment;"]
[81563,"'C1orf21'",32,28,49,36.3333333333333,{"$nulls":5},"GO:0005515///protein binding","GO:0006396///RNA processing","chromosome 1 open reading frame 21","[CA021_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C1orf21; AltName: Full=Cell proliferation-inducing gene 13 protein;+++[A0A024R926_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 21, isoform CRA_a {ECO:0000313|EMBL:EAW91177.1};"]
[81567,"'TXNDC5'",11736,10741,9218,10565,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005623///cell+++GO:0005576///extracellular region+++GO:0043202///lysosomal lumen+++GO:0005788///endoplasmic reticulum lumen+++GO:0070062///extracellular exosome+++GO:0035578///azurophil granule lumen+++GO:0005783///endoplasmic reticulum","GO:0016853///isomerase activity+++GO:0005515///protein binding","GO:0043277///apoptotic cell clearance+++GO:0045454///cell redox homeostasis+++GO:0043312///neutrophil degranulation+++GO:0043066///negative regulation of apoptotic process","thioredoxin domain containing 5","[TXND5_HUMAN|Reviewed]RecName: Full=Thioredoxin domain-containing protein 5; AltName: Full=Endoplasmic reticulum resident protein 46; Short=ER protein 46; Short=ERp46; AltName: Full=Thioredoxin-like protein p46; Flags: Precursor;+++[A0A024QZV0_HUMAN|Unreviewed]SubName: Full=HCG1811539, isoform CRA_b {ECO:0000313|EMBL:EAW55222.1};+++[Q6EHZ3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAR99514.1};+++[Q86UY0_HUMAN|Unreviewed]SubName: Full=TXNDC5 protein {ECO:0000313|EMBL:AAH52310.1};"]
[81622,"'UNC93B1'",367,461,365,397.666666666667,{"$nulls":4},"GO:0032009///early phagosome+++GO:0031410///cytoplasmic vesicle+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0045335///phagocytic vesicle+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0035325///Toll-like receptor binding+++GO:0008565///protein transporter activity","GO:0051607///defense response to virus+++GO:0034154///toll-like receptor 7 signaling pathway+++GO:0002376///immune system process+++GO:0002224///toll-like receptor signaling pathway+++GO:0002250///adaptive immune response+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0045087///innate immune response+++GO:0006886///intracellular protein transport+++GO:0034162///toll-like receptor 9 signaling pathway","unc-93 homolog B1, TLR signaling regulator","[UN93B_HUMAN|Reviewed]RecName: Full=Protein unc-93 homolog B1; Short=Unc-93B1; Short=hUNC93B1;+++[E9PNE5_HUMAN|Unreviewed]SubName: Full=Protein unc-93 homolog B1 {ECO:0000313|Ensembl:ENSP00000437195}; Flags: Fragment;+++[E9PR93_HUMAN|Unreviewed]SubName: Full=Protein unc-93 homolog B1 {ECO:0000313|Ensembl:ENSP00000434294};+++[Q05BS6_HUMAN|Unreviewed]SubName: Full=UNC93B1 protein {ECO:0000313|EMBL:AAH33623.1}; Flags: Fragment;+++[Q58F16_HUMAN|Unreviewed]SubName: Full=UNC93B1 protein {ECO:0000313|EMBL:AAH25669.1}; Flags: Fragment;"]
[8165,"'AKAP1'",199,199,167,188.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005741///mitochondrial outer membrane","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0034237///protein kinase A regulatory subunit binding","GO:0010738///regulation of protein kinase A signaling+++GO:0007596///blood coagulation","A-kinase anchoring protein 1","[AKAP1_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 1, mitochondrial; AltName: Full=A-kinase anchor protein 149 kDa; Short=AKAP 149 {ECO:0000303|PubMed:8769136}; AltName: Full=Dual specificity A-kinase-anchoring protein 1; Short=D-AKAP-1; AltName: Full=Protein kinase A-anchoring protein 1; Short=PRKA1; AltName: Full=Spermatid A-kinase anchor protein 84; Short=S-AKAP84 {ECO:0000303|PubMed:7499250}; Flags: Precursor;+++[A0A0G2JLF7_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000461418}; Flags: Fragment;+++[A0A140VK05_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 5 {ECO:0000313|EMBL:AEE61142.1};+++[B4DN86_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56047, highly similar to A kinase anchor protein 1, mitochondrial {ECO:0000313|EMBL:BAG60148.1};+++[I3L0K6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458164}; Flags: Fragment;+++[I3L0V5_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458370}; Flags: Fragment;+++[I3L0W0_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000458378}; Flags: Fragment;+++[I3L2A2_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000459521}; Flags: Fragment;+++[I3L2N7_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000459808}; Flags: Fragment;+++[I3L364_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460209}; Flags: Fragment;+++[I3L3K1_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460514}; Flags: Fragment;+++[I3L3L9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460557}; Flags: Fragment;+++[I3L3V6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000460762}; Flags: Fragment;+++[I3NI36_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000461854}; Flags: Fragment;"]
[81846,"'SBF2'",419,298,373,363.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0016020///membrane+++GO:0005774///vacuolar membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019902///phosphatase binding+++GO:0019208///phosphatase regulator activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0035091///phosphatidylinositol binding","GO:0051262///protein tetramerization+++GO:0043087///regulation of GTPase activity+++GO:0042552///myelination","SET binding factor 2","[MTMRD_HUMAN|Reviewed]RecName: Full=Myotubularin-related protein 13; AltName: Full=SET-binding factor 2;+++[H0Y767_HUMAN|Unreviewed]SubName: Full=Myotubularin-related protein 13 {ECO:0000313|Ensembl:ENSP00000410478}; Flags: Fragment;+++[H0YD05_HUMAN|Unreviewed]SubName: Full=Myotubularin-related protein 13 {ECO:0000313|Ensembl:ENSP00000432643}; Flags: Fragment;+++[H0YDZ1_HUMAN|Unreviewed]SubName: Full=Myotubularin-related protein 13 {ECO:0000313|Ensembl:ENSP00000434620}; Flags: Fragment;"]
[81855,"'SFXN3'",1364,1504,1452,1440,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0015075///ion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0055072///iron ion homeostasis+++GO:0006811///ion transport","sideroflexin 3","[SFXN3_HUMAN|Reviewed]RecName: Full=Sideroflexin-3;+++[A0A0A0MS41_HUMAN|Unreviewed]RecName: Full=Sideroflexin {ECO:0000256|RuleBase:RU362000};+++[A0A1P0AYU5_HUMAN|Unreviewed]RecName: Full=Sideroflexin {ECO:0000256|RuleBase:RU362000};+++[S4R3N9_HUMAN|Unreviewed]SubName: Full=Sideroflexin-3 {ECO:0000313|Ensembl:ENSP00000474564};"]
[8200,"'GDF5'",215,192,178,195,"04350///TGF-beta signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04390///Hippo signaling pathway","H00483///Brachydactyly type C+++H00466///Grebe dysplasia+++H00484///Other brachydactylies+++H00467///Fibular hypoplasia and complex brachydactyly","M00679///BMP signaling",null,"GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane","GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0005102///signaling receptor binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0036122///BMP binding","GO:0045666///positive regulation of neuron differentiation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0043408///regulation of MAPK cascade+++GO:0043932///ossification involved in bone remodeling+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0051216///cartilage development+++GO:0030326///embryonic limb morphogenesis+++GO:2001054///negative regulation of mesenchymal cell apoptotic process+++GO:0002062///chondrocyte differentiation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0009612///response to mechanical stimulus+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0035136///forelimb morphogenesis+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0040014///regulation of multicellular organism growth+++GO:0048468///cell development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0030509///BMP signaling pathway+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0007267///cell-cell signaling+++GO:0042981///regulation of apoptotic process+++GO:0035137///hindlimb morphogenesis+++GO:0060395///SMAD protein signal transduction+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0060591///chondroblast differentiation","growth differentiation factor 5","[GDF5_HUMAN|Reviewed]RecName: Full=Growth/differentiation factor 5; Short=GDF-5; AltName: Full=Bone morphogenetic protein 14; Short=BMP-14; AltName: Full=Cartilage-derived morphogenetic protein 1; Short=CDMP-1; AltName: Full=Lipopolysaccharide-associated protein 4; Short=LAP-4; Short=LPS-associated protein 4; AltName: Full=Radotermin; Flags: Precursor;+++[D3YQT0_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39269.1}; Flags: Fragment;+++[D3YQY5_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39324.1}; Flags: Fragment;+++[D3YQZ2_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39331.1}; Flags: Fragment;+++[D3YR12_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39351.1}; Flags: Fragment;+++[D3YR58_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39397.1}; Flags: Fragment;+++[D3YR72_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39411.1}; Flags: Fragment;+++[D3YR76_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39415.1}; Flags: Fragment;+++[D3YR87_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39426.1}; Flags: Fragment;+++[D3YRA6_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39445.1}; Flags: Fragment;+++[D3YRI8_HUMAN|Unreviewed]SubName: Full=GDF5 {ECO:0000313|EMBL:ADD39527.1}; Flags: Fragment;+++[F1T0J1_HUMAN|Unreviewed]SubName: Full=Growth/differentiation factor 5 {ECO:0000313|EMBL:BAJ84065.1};+++[Q2NKW7_HUMAN|Unreviewed]SubName: Full=GDF5 protein {ECO:0000313|EMBL:AAI11567.1}; Flags: Fragment;"]
[8216,"'LZTR1'",1085,1214,1159,1152.66666666667,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0009653///anatomical structure morphogenesis","leucine zipper like transcription regulator 1","[LZTR1_HUMAN|Reviewed]RecName: Full=Leucine-zipper-like transcriptional regulator 1; Short=LZTR-1;+++[A0A2R8Y4K9_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000494153}; Flags: Fragment;+++[A0A2R8Y656_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000495284}; Flags: Fragment;+++[A0A2R8Y7K3_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000496175}; Flags: Fragment;+++[A0A2R8YCD2_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000493479}; Flags: Fragment;+++[F8WB67_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000397247};+++[F8WCB6_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000406466};+++[F8WEQ8_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000393765}; Flags: Fragment;+++[H7BZQ9_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000390836}; Flags: Fragment;+++[H7C0X1_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000397252}; Flags: Fragment;+++[H7C305_HUMAN|Unreviewed]SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|Ensembl:ENSP00000408789}; Flags: Fragment;"]
[8233,"'ZRSR2'",166.87,187.87,152.53,169.09,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0089701///U2AF+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005654///nucleoplasm","GO:0030628///pre-mRNA 3'-splice site binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000245///spliceosomal complex assembly","zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2","[U2AFM_HUMAN|Reviewed]RecName: Full=U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2; AltName: Full=CCCH type zinc finger, RNA-binding motif and serine/arginine rich protein 2; AltName: Full=Renal carcinoma antigen NY-REN-20; AltName: Full=U2(RNU2) small nuclear RNA auxiliary factor 1-like 2; AltName: Full=U2AF35-related protein; Short=URP;+++[A6NDW0_HUMAN|Unreviewed]SubName: Full=U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 {ECO:0000313|Ensembl:ENSP00000369664};+++[Q86VN0_HUMAN|Unreviewed]SubName: Full=Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 {ECO:0000313|EMBL:AAH50451.2};"]
[8292,"'COLQ'",32,50,44,42,"04146///Peroxisome+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0005581///collagen trimer+++GO:0031594///neuromuscular junction+++GO:0031012///extracellular matrix+++GO:0005604///basement membrane+++GO:0043083///synaptic cleft+++GO:0005615///extracellular space","GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0005201///extracellular matrix structural constituent","GO:0042135///neurotransmitter catabolic process+++GO:0090150///establishment of protein localization to membrane+++GO:0001507///acetylcholine catabolic process in synaptic cleft+++GO:0030198///extracellular matrix organization+++GO:0008582///regulation of synaptic growth at neuromuscular junction+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering","collagen like tail subunit of asymmetric acetylcholinesterase","[COLQ_HUMAN|Reviewed]RecName: Full=Acetylcholinesterase collagenic tail peptide; AltName: Full=AChE Q subunit; AltName: Full=Acetylcholinesterase-associated collagen; Flags: Precursor;+++[A0A024R2P2_HUMAN|Unreviewed]SubName: Full=Collagen-like tail subunit (Single strand of homotrimer) of asymmetric acetylcholinesterase, isoform CRA_e {ECO:0000313|EMBL:EAW64249.1};+++[A0A0C4DGS2_HUMAN|Unreviewed]SubName: Full=Acetylcholinesterase collagenic tail peptide {ECO:0000313|Ensembl:ENSP00000474271};+++[S4R408_HUMAN|Unreviewed]SubName: Full=Acetylcholinesterase collagenic tail peptide {ECO:0000313|Ensembl:ENSP00000474936}; Flags: Fragment;"]
[8312,"'AXIN1'",555,685,591,610.333333333333,"05165///Human papillomavirus infection+++05200///Pathways in cancer+++05217///Basal cell carcinoma+++04310///Wnt signaling pathway+++04390///Hippo signaling pathway+++05210///Colorectal cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05224///Breast cancer+++04934///Cushing's syndrome+++05225///Hepatocellular carcinoma+++05213///Endometrial cancer+++05226///Gastric cancer","H00048///Hepatocellular carcinoma+++H00934///Caudal duplication anomaly+++H01667///Medulloblastoma",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0030877///beta-catenin destruction complex+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0071944///cell periphery+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0016328///lateral plasma membrane+++GO:0016020///membrane","GO:0031625///ubiquitin protein ligase binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0042802///identical protein binding+++GO:0070411///I-SMAD binding+++GO:0042803///protein homodimerization activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0035591///signaling adaptor activity+++GO:0046332///SMAD binding+++GO:0019899///enzyme binding+++GO:0070016///armadillo repeat domain binding+++GO:0008013///beta-catenin binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:0016055///Wnt signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:1904885///beta-catenin destruction complex assembly+++GO:0031398///positive regulation of protein ubiquitination+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0045732///positive regulation of protein catabolic process+++GO:0007165///signal transduction+++GO:1904886///beta-catenin destruction complex disassembly+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006915///apoptotic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007275///multicellular organism development+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0046330///positive regulation of JNK cascade+++GO:0032147///activation of protein kinase activity+++GO:0034622///cellular protein-containing complex assembly+++GO:0030111///regulation of Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway","axin 1","[AXIN1_HUMAN|Reviewed]RecName: Full=Axin-1; AltName: Full=Axis inhibition protein 1; Short=hAxin;+++[A0A0S2Z4M1_HUMAN|Unreviewed]SubName: Full=Axin 1 isoform 3 {ECO:0000313|EMBL:ALQ33873.1}; Flags: Fragment;+++[A0A0S2Z4R0_HUMAN|Unreviewed]SubName: Full=Axin 1 isoform 2 {ECO:0000313|EMBL:ALQ33872.1}; SubName: Full=Axin 1, isoform CRA_b {ECO:0000313|EMBL:EAW85836.1}; Flags: Fragment;+++[A0A0S2Z4S3_HUMAN|Unreviewed]SubName: Full=Axin 1 isoform 1 {ECO:0000313|EMBL:ALQ33871.1}; SubName: Full=Axin 1, isoform CRA_a {ECO:0000313|EMBL:EAW85835.1}; Flags: Fragment;+++[B1AH42_HUMAN|Unreviewed]SubName: Full=Axin 1 {ECO:0000313|EMBL:CAQ09649.1}; Flags: Fragment;+++[H0Y830_HUMAN|Unreviewed]SubName: Full=Axin-1 {ECO:0000313|Ensembl:ENSP00000416835}; Flags: Fragment;"]
[8339,"'HIST1H2BG'",7,6,0,4.33333333333333,"05322///Systemic lupus erythematosus+++05203///Viral carcinogenesis+++05034///Alcoholism",{"$nulls":3},"GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000786///nucleosome+++GO:0005615///extracellular space","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0042802///identical protein binding","GO:0016567///protein ubiquitination+++GO:0002227///innate immune response in mucosa+++GO:0050830///defense response to Gram-positive bacterium+++GO:0019731///antibacterial humoral response+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0006334///nucleosome assembly","histone cluster 1 H2B family member g","[H2B1C_HUMAN|Reviewed]RecName: Full=Histone H2B type 1-C/E/F/G/I; AltName: Full=Histone H2B.1 A; AltName: Full=Histone H2B.a; Short=H2B/a; AltName: Full=Histone H2B.g; Short=H2B/g; AltName: Full=Histone H2B.h; Short=H2B/h; AltName: Full=Histone H2B.k; Short=H2B/k; AltName: Full=Histone H2B.l; Short=H2B/l;+++[B2R4S9_HUMAN|Unreviewed]RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};"]
[83440,"'ADPGK'",622,674,757.04,684.346666666667,"01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01100///Metabolic pathways",null,"M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate","R09085///ADP:D-glucose 6-phosphotransferase   alpha-D-Glucose + ADP <=> alpha-D-Glucose 6-phosphate + AMP+++R05804///ADP:D-glucose 6-phosphotransferase   ADP + D-Glucose <=> AMP + D-Glucose 6-phosphate+++R09086///ADP:D-glucose 6-phosphotransferase   beta-D-Glucose + ADP <=> beta-D-Glucose 6-phosphate + AMP","GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0043843///ADP-specific glucokinase activity","GO:0016310///phosphorylation+++GO:0061621///canonical glycolysis+++GO:0006096///glycolytic process+++GO:0006006///glucose metabolic process+++GO:0005975///carbohydrate metabolic process","ADP dependent glucokinase","[ADPGK_HUMAN|Reviewed]RecName: Full=ADP-dependent glucokinase; Short=ADP-GK; Short=ADPGK; EC=2.7.1.147; AltName: Full=RbBP-35; Flags: Precursor;+++[H3BN66_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase, isoform CRA_e {ECO:0000313|EMBL:EAW77918.1};+++[H3BRS6_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000456387}; Flags: Fragment;+++[H3BTH4_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000457175}; Flags: Fragment;+++[H3BU35_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000457447}; Flags: Fragment;+++[H3BUC3_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000457572}; Flags: Fragment;"]
[8351,"'HIST1H3D'",14.23,6.21,0,6.81333333333333,"05322///Systemic lupus erythematosus+++05202///Transcriptional misregulation in cancer+++05034///Alcoholism","H01470///Giant cell tumor of bone",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000228///nuclear chromosome+++GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005840///ribosome+++GO:0000786///nucleosome+++GO:0022627///cytosolic small ribosomal subunit+++GO:0032991///protein-containing complex+++GO:0000788///nuclear nucleosome+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005925///focal adhesion+++GO:0000790///nuclear chromatin+++GO:0005576///extracellular region","GO:0045296///cadherin binding+++GO:0003723///RNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding","GO:0060968///regulation of gene silencing+++GO:0051290///protein heterotetramerization+++GO:0060964///regulation of gene silencing by miRNA+++GO:0006325///chromatin organization+++GO:0007596///blood coagulation+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006334///nucleosome assembly+++GO:0000183///chromatin silencing at rDNA+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0006413///translational initiation+++GO:0032200///telomere organization+++GO:0006342///chromatin silencing+++GO:0006412///translation+++GO:0000028///ribosomal small subunit assembly+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0044267///cellular protein metabolic process","histone cluster 1 H3 family member d","[H31_HUMAN|Reviewed]RecName: Full=Histone H3.1; AltName: Full=Histone H3/a; AltName: Full=Histone H3/b; AltName: Full=Histone H3/c; AltName: Full=Histone H3/d; AltName: Full=Histone H3/f; AltName: Full=Histone H3/h; AltName: Full=Histone H3/i; AltName: Full=Histone H3/j; AltName: Full=Histone H3/k; AltName: Full=Histone H3/l;"]
[83543,"'AIF1L'",35,38,47,40,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005925///focal adhesion+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005884///actin filament+++GO:0032587///ruffle membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0032991///protein-containing complex+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton","GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0097178///ruffle assembly+++GO:0051017///actin filament bundle assembly","allograft inflammatory factor 1 like","[AIF1L_HUMAN|Reviewed]RecName: Full=Allograft inflammatory factor 1-like; AltName: Full=Ionized calcium-binding adapter molecule 2;+++[A6PVM9_HUMAN|Unreviewed]SubName: Full=Allograft inflammatory factor 1-like {ECO:0000313|Ensembl:ENSP00000361375};+++[H7C605_HUMAN|Unreviewed]SubName: Full=Allograft inflammatory factor 1-like {ECO:0000313|Ensembl:ENSP00000361388};+++[Q5JUP1_HUMAN|Unreviewed]SubName: Full=Allograft inflammatory factor 1-like {ECO:0000313|Ensembl:ENSP00000361371};+++[Q5JUP3_HUMAN|Unreviewed]SubName: Full=Allograft inflammatory factor 1-like {ECO:0000313|Ensembl:ENSP00000361372};"]
[83637,"'ZMIZ2'",5094,5091,4845,5010,{"$nulls":4},"GO:0043596///nuclear replication fork+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008270///zinc ion binding","GO:0045944///positive regulation of transcription by RNA polymerase II","zinc finger MIZ-type containing 2","[ZMIZ2_HUMAN|Reviewed]RecName: Full=Zinc finger MIZ domain-containing protein 2; AltName: Full=PIAS-like protein Zimp7;+++[A0A087X127_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000483853};+++[A3KMG8_HUMAN|Unreviewed]SubName: Full=ZMIZ2 protein {ECO:0000313|EMBL:AAI31781.1}; Flags: Fragment;+++[C9JDA5_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415501}; Flags: Fragment;+++[D4YW75_HUMAN|Unreviewed]SubName: Full=TRAFIP20 {ECO:0000313|EMBL:AAQ15172.1};+++[E7EWM3_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000396601};+++[F8WC48_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000406820};"]
[83642,"'SELENOO'",487,512,473,490.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01880///Autosomal recessive microcephaly and chorioretinopathy",null,null,"GO:0005739///mitochondrion",null,null,"selenoprotein O","[SELO_HUMAN|Reviewed]RecName: Full=Selenoprotein O {ECO:0000303|PubMed:27645994}; Short=SelO {ECO:0000303|PubMed:12775843, ECO:0000303|PubMed:24751718, ECO:0000303|PubMed:27645994};+++[A0A087X0Q9_HUMAN|Unreviewed]SubName: Full=Selenoprotein O {ECO:0000313|Ensembl:ENSP00000483593};"]
[83690,"'CRISPLD1'",3332,2152,4616,3366.66666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0003674///molecular_function","GO:0060325///face morphogenesis","cysteine rich secretory protein LCCL domain containing 1","[CRLD1_HUMAN|Reviewed]RecName: Full=Cysteine-rich secretory protein LCCL domain-containing 1; AltName: Full=CocoaCrisp; AltName: Full=Cysteine-rich secretory protein 10; Short=CRISP-10; AltName: Full=LCCL domain-containing cysteine-rich secretory protein 1; AltName: Full=Trypsin inhibitor Hl; Flags: Precursor;+++[B7Z8V9_HUMAN|Unreviewed]SubName: Full=Cysteine-rich secretory protein LCCL domain-containing 1 {ECO:0000313|Ensembl:ENSP00000430105}; SubName: Full=cDNA FLJ57290, highly similar to Homo sapiens cysteine-rich secretory protein LCCL domain containing 1 (CRISPLD1), mRNA {ECO:0000313|EMBL:BAH14095.1};+++[E5RJS4_HUMAN|Unreviewed]SubName: Full=Cysteine-rich secretory protein LCCL domain-containing 1 {ECO:0000313|Ensembl:ENSP00000430504}; Flags: Fragment;"]
[83732,"'RIOK1'",104,139,117,120,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0030688///preribosome, small subunit precursor+++GO:0005654///nucleoplasm+++GO:0034708///methyltransferase complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity","GO:0042274///ribosomal small subunit biogenesis+++GO:0042254///ribosome biogenesis+++GO:0030490///maturation of SSU-rRNA+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:2000234///positive regulation of rRNA processing","RIO kinase 1","[RIOK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase RIO1; EC=2.7.11.1 {ECO:0000269|PubMed:22072790}; EC=3.6.3.-; AltName: Full=RIO kinase 1;+++[E9PFQ8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase RIO1 {ECO:0000313|Ensembl:ENSP00000418263};"]
[83786,"'FRMD8'",329,313,346,329.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton","GO:0005515///protein binding",null,"FERM domain containing 8","[FRMD8_HUMAN|Reviewed]RecName: Full=FERM domain-containing protein 8;+++[A8K6L3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76883, highly similar to Homo sapiens FKSG44 gene (FKSG44), mRNA {ECO:0000313|EMBL:BAF84367.1};+++[E9PRA3_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000434274}; Flags: Fragment;+++[E9PRP1_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000435991}; Flags: Fragment;+++[E9PS62_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000435913}; Flags: Fragment;+++[Q8N4M4_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000433479}; SubName: Full=FRMD8 protein {ECO:0000313|EMBL:AAH33851.1};"]
[83871,"'RAB34'",1309,1458,1295,1354,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045335///phagocytic vesicle+++GO:0005795///Golgi stack+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0031985///Golgi cisterna+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0032587///ruffle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031982///vesicle+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0042995///cell projection","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0030742///GTP-dependent protein binding+++GO:0017160///Ral GTPase binding+++GO:0005515///protein binding","GO:0045880///positive regulation of smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0006886///intracellular protein transport+++GO:0019882///antigen processing and presentation+++GO:0015031///protein transport+++GO:0032418///lysosome localization+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0044351///macropinocytosis+++GO:0090382///phagosome maturation+++GO:0072659///protein localization to plasma membrane+++GO:0032482///Rab protein signal transduction+++GO:0090385///phagosome-lysosome fusion","RAB34, member RAS oncogene family","[NARR_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-34, isoform NARR; AltName: Full=Nine amino-acid residue-repeats;+++[RAB34_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-34; AltName: Full=Ras-related protein Rab-39; AltName: Full=Ras-related protein Rah;+++[A0A024QZ68_HUMAN|Unreviewed]SubName: Full=RAB34, member RAS oncogene family, isoform CRA_b {ECO:0000313|EMBL:EAW51130.1};+++[A0A1B0GTQ2_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000489794};+++[A0A1B0GVI6_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000490529};+++[A0A1B0GWB1_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000490855};+++[A0A1C7CYW6_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000378664};+++[B4DNC0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61141, highly similar to Ras-related protein Rab-34 {ECO:0000313|EMBL:BAG60182.1};+++[C9JBG0_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000398706}; Flags: Fragment;+++[C9JY26_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000407953}; Flags: Fragment;+++[E7ES60_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000413156};+++[H7C0Y7_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000397499};+++[J3QLC6_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000463488}; Flags: Fragment;+++[K7EIF2_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000464723}; Flags: Fragment;+++[K7EJW7_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000465352}; Flags: Fragment;+++[Q6NXT3_HUMAN|Unreviewed]SubName: Full=RAB34 protein {ECO:0000313|EMBL:AAH66904.1};+++[Q96PJ7_HUMAN|Unreviewed]SubName: Full=Ras-related GTP-binding protein RAB39 {ECO:0000313|EMBL:AAL05587.1}; SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000487160};+++[V9GY61_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000476427}; Flags: Fragment;"]
[83903,"'HASPIN'",14,8,5,9,{"$nulls":4},"GO:0005819///spindle+++GO:0005694///chromosome+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0072354///histone kinase activity (H3-T3 specific)+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity","GO:0016310///phosphorylation+++GO:0006325///chromatin organization+++GO:2000751///histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0007064///mitotic sister chromatid cohesion+++GO:0035556///intracellular signal transduction+++GO:0007049///cell cycle+++GO:0006468///protein phosphorylation","histone H3 associated protein kinase","[HASP_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase haspin; EC=2.7.11.1; AltName: Full=Germ cell-specific gene 2 protein; AltName: Full=H-haspin; AltName: Full=Haploid germ cell-specific nuclear protein kinase;+++[A0PJ70_HUMAN|Unreviewed]SubName: Full=GSG2 protein {ECO:0000313|EMBL:AAH16626.1}; Flags: Fragment;"]
[8396,"'PIP4K2B'",1133,1081,1104,1106,"04810///Regulation of actin cytoskeleton+++00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system",null,null,"R05803///ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase   ATP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate","GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0005776///autophagosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum","GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0042803///protein homodimerization activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:0052811///1-phosphatidylinositol-3-phosphate 4-kinase activity+++GO:0016309///1-phosphatidylinositol-5-phosphate 4-kinase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0007166///cell surface receptor signaling pathway+++GO:2000786///positive regulation of autophagosome assembly+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0010506///regulation of autophagy+++GO:0006644///phospholipid metabolic process+++GO:0046488///phosphatidylinositol metabolic process+++GO:0016310///phosphorylation+++GO:0006661///phosphatidylinositol biosynthetic process","phosphatidylinositol-5-phosphate 4-kinase type 2 beta","[PI42B_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 beta; EC=2.7.1.149; AltName: Full=1-phosphatidylinositol 5-phosphate 4-kinase 2-beta; AltName: Full=Diphosphoinositide kinase 2-beta; AltName: Full=Phosphatidylinositol 5-phosphate 4-kinase type II beta; Short=PI(5)P 4-kinase type II beta; Short=PIP4KII-beta; AltName: Full=PtdIns(5)P-4-kinase isoform 2-beta;+++[A0A087WT35_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 beta {ECO:0000313|Ensembl:ENSP00000477549}; Flags: Fragment;"]
[84002,"'B3GNT5'",5,1,3,3,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++01100///Metabolic pathways",null,"M00071///Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer+++M00070///Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer","R05971///UDP-N-acetyl-D-glucosamine + Lactosylceramide <=> UDP + Lc3Cer","GO:0005622///intracellular+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008457///beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity+++GO:0047256///lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity","GO:0006486///protein glycosylation+++GO:0016266///O-glycan processing+++GO:0007420///brain development+++GO:0030311///poly-N-acetyllactosamine biosynthetic process+++GO:0007275///multicellular organism development+++GO:0007417///central nervous system development+++GO:0009247///glycolipid biosynthetic process","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5","[B3GN5_HUMAN|Reviewed]RecName: Full=Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase; EC=2.4.1.206; AltName: Full=Lactotriaosylceramide synthase; Short=Lc(3)Cer synthase; Short=Lc3 synthase; AltName: Full=UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5; Short=BGnT-5; Short=Beta-1,3-Gn-T5; Short=Beta-1,3-N-acetylglucosaminyltransferase 5; Short=Beta3Gn-T5;+++[C9IYY0_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[C9J368_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[C9J5K2_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;"]
[84067,"'FAM160A2'",372,383,435,396.666666666667,"04137///Mitophagy - animal+++04740///Olfactory transduction+++04140///Autophagy - animal",{"$nulls":3},"GO:0070695///FHF complex+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0007040///lysosome organization+++GO:0007032///endosome organization+++GO:0015031///protein transport+++GO:0008333///endosome to lysosome transport+++GO:0045022///early endosome to late endosome transport","family with sequence similarity 160 member A2","[F16A2_HUMAN|Reviewed]RecName: Full=FTS and Hook-interacting protein; Short=FHIP; AltName: Full=Protein FAM160A2;+++[E9PJK5_HUMAN|Unreviewed]SubName: Full=FTS and Hook-interacting protein {ECO:0000313|Ensembl:ENSP00000431773};"]
[84083,"'ZRANB3'",65,52,64,60.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00792///Warburg micro syndrome+++H00271///Polymicrogyria",null,null,"GO:0005634///nucleus+++GO:0043596///nuclear replication fork+++GO:0005694///chromosome","GO:0004518///nuclease activity+++GO:0036310///annealing helicase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0003824///catalytic activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0003678///DNA helicase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0004519///endonuclease activity+++GO:0005524///ATP binding+++GO:0003676///nucleic acid binding","GO:0036292///DNA rewinding+++GO:0008152///metabolic process+++GO:0032508///DNA duplex unwinding+++GO:0000733///DNA strand renaturation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0045910///negative regulation of DNA recombination+++GO:0031297///replication fork processing+++GO:0009411///response to UV+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0048478///replication fork protection","zinc finger RANBP2-type containing 3","[ZRAB3_HUMAN|Reviewed]RecName: Full=DNA annealing helicase and endonuclease ZRANB3 {ECO:0000305}; AltName: Full=Annealing helicase 2 {ECO:0000303|PubMed:21078962}; Short=AH2 {ECO:0000303|PubMed:21078962}; AltName: Full=Zinc finger Ran-binding domain-containing protein 3 {ECO:0000305}; Includes: RecName: Full=DNA annealing helicase ZRANB3 {ECO:0000305}; EC=3.6.4.- {ECO:0000269|PubMed:22704558, ECO:0000269|PubMed:22705370}; Includes: RecName: Full=Endonuclease ZRANB3 {ECO:0000305}; EC=3.1.-.- {ECO:0000269|PubMed:22759634};+++[F5GYN7_HUMAN|Unreviewed]SubName: Full=DNA annealing helicase and endonuclease ZRANB3 {ECO:0000313|Ensembl:ENSP00000441320}; SubName: Full=Zinc finger, RAN-binding domain containing 3, isoform CRA_g {ECO:0000313|EMBL:EAX11636.1};+++[F8WCT9_HUMAN|Unreviewed]SubName: Full=DNA annealing helicase and endonuclease ZRANB3 {ECO:0000313|Ensembl:ENSP00000384245};"]
[84129,"'ACAD11'",231,207,284,240.666666666667,{"$nulls":4},"GO:0031966///mitochondrial membrane+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005743///mitochondrial inner membrane+++GO:0005777///peroxisome","GO:0017099///very-long-chain-acyl-CoA dehydrogenase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0070991///medium-chain-acyl-CoA dehydrogenase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0004466///long-chain-acyl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0003995///acyl-CoA dehydrogenase activity","GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0006635///fatty acid beta-oxidation+++GO:0055114///oxidation-reduction process","acyl-CoA dehydrogenase family member 11","[ACD11_HUMAN|Reviewed]RecName: Full=Acyl-CoA dehydrogenase family member 11; Short=ACAD-11; EC=1.3.99.-;+++[D6RDI8_HUMAN|Unreviewed]SubName: Full=Acyl-CoA dehydrogenase family member 11 {ECO:0000313|Ensembl:ENSP00000420907};+++[F8WEV0_HUMAN|Unreviewed]SubName: Full=Acyl-CoA dehydrogenase family member 11 {ECO:0000313|Ensembl:ENSP00000419973};+++[H0Y9C6_HUMAN|Unreviewed]SubName: Full=Acyl-CoA dehydrogenase family member 11 {ECO:0000313|Ensembl:ENSP00000423796}; Flags: Fragment;+++[Q08AE9_HUMAN|Unreviewed]SubName: Full=ACAD11 protein {ECO:0000313|EMBL:AAI25206.1};"]
[84153,"'RNASEH2C'",470,486,469,475,"03030///DNA replication","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0005634///nucleus+++GO:0032299///ribonuclease H2 complex","GO:0004402///histone acetyltransferase activity+++GO:0016407///acetyltransferase activity+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0070491///repressing transcription factor binding+++GO:0003713///transcription coactivator activity","GO:0006401///RNA catabolic process","ribonuclease H2 subunit C","[RNH2C_HUMAN|Reviewed]RecName: Full=Ribonuclease H2 subunit C; Short=RNase H2 subunit C; AltName: Full=Aicardi-Goutieres syndrome 3 protein; Short=AGS3; AltName: Full=RNase H1 small subunit; AltName: Full=Ribonuclease HI subunit C;+++[A0A024R5B3_HUMAN|Unreviewed]SubName: Full=AYP1 protein, isoform CRA_b {ECO:0000313|EMBL:EAW74435.1};+++[E9PN81_HUMAN|Unreviewed]SubName: Full=Ribonuclease H2 subunit C {ECO:0000313|Ensembl:ENSP00000432897};+++[H0YCP5_HUMAN|Unreviewed]SubName: Full=Ribonuclease H2 subunit C {ECO:0000313|Ensembl:ENSP00000432081}; Flags: Fragment;+++[H0YEF3_HUMAN|Unreviewed]SubName: Full=Ribonuclease H2 subunit C {ECO:0000313|Ensembl:ENSP00000435717}; Flags: Fragment;"]
[84188,"'FAR1'",346,211,237,264.666666666667,"04146///Peroxisome+++04212///Longevity regulating pathway - worm+++00073///Cutin, suberine and wax biosynthesis","H02100///Peroxisomal fatty acyl-CoA reductase 1 disorder+++H00207///Rhizomelic chondrodysplasia punctata",null,"R09470///long-chain-primary-alcohol:NADP+ oxidoreductase (CoA-acylating)   Long-chain acyl-CoA + 2 NADPH + 2 H+ <=> Primary alcohol + 2 NADP+ + CoA","GO:0005782///peroxisomal matrix+++GO:0016020///membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0016021///integral component of membrane","GO:0080019///fatty-acyl-CoA reductase (alcohol-forming) activity+++GO:0016491///oxidoreductase activity+++GO:0102965///alcohol-forming fatty acyl-CoA reductase activity","GO:0010025///wax biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0046474///glycerophospholipid biosynthetic process+++GO:0035336///long-chain fatty-acyl-CoA metabolic process+++GO:0008611///ether lipid biosynthetic process","fatty acyl-CoA reductase 1","[FACR1_HUMAN|Reviewed]RecName: Full=Fatty acyl-CoA reductase 1 {ECO:0000305|PubMed:15220348}; EC=1.2.1.84 {ECO:0000269|PubMed:15220348, ECO:0000269|PubMed:24108123}; AltName: Full=Male sterility domain-containing protein 2 {ECO:0000312|HGNC:HGNC:26222};+++[E9PNW8_HUMAN|Unreviewed]RecName: Full=Fatty acyl-CoA reductase {ECO:0000256|RuleBase:RU363097}; EC=1.2.1.84 {ECO:0000256|RuleBase:RU363097}; Flags: Fragment;+++[E9PPB8_HUMAN|Unreviewed]SubName: Full=Fatty acyl-CoA reductase 1 {ECO:0000313|Ensembl:ENSP00000434624};"]
[84217,"'ZMYND12'",18,10,22,16.6666666666667,"04140///Autophagy - animal+++00770///Pantothenate and CoA biosynthesis+++01100///Metabolic pathways+++04137///Mitophagy - animal",null,"M00120///Coenzyme A biosynthesis, pantothenate => CoA","R04230///(R)-4'-phosphopantothenate:L-cysteine ligase (ATP-utilizing) ATP + D-4'-Phosphopantothenate + L-Cysteine <=> AMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine","GO:0005622///intracellular","GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger MYND-type containing 12","[ZMY12_HUMAN|Reviewed]RecName: Full=Zinc finger MYND domain-containing protein 12;+++[A0A087WUN3_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000478789};+++[A0A087WZE7_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000482602};+++[B4DX70_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58334, highly similar to Zinc finger MYND domain-containing protein 12 {ECO:0000313|EMBL:BAG63282.1};"]
[84248,"'FYTTD1'",672,540,516,576,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005623///cell+++GO:0005654///nucleoplasm","GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0051028///mRNA transport+++GO:0006406///mRNA export from nucleus","forty-two-three domain containing 1","[UIF_HUMAN|Reviewed]RecName: Full=UAP56-interacting factor; AltName: Full=Forty-two-three domain-containing protein 1; Short=Protein 40-2-3;+++[A0A024R9K4_HUMAN|Unreviewed]SubName: Full=Forty-two-three domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW92241.1};+++[H9KVC1_HUMAN|Unreviewed]SubName: Full=UAP56-interacting factor {ECO:0000313|Ensembl:ENSP00000389557}; Flags: Fragment;+++[H9KVC6_HUMAN|Unreviewed]SubName: Full=UAP56-interacting factor {ECO:0000313|Ensembl:ENSP00000399896}; Flags: Fragment;+++[H9KVD1_HUMAN|Unreviewed]SubName: Full=UAP56-interacting factor {ECO:0000313|Ensembl:ENSP00000409257};+++[H9KVD5_HUMAN|Unreviewed]SubName: Full=UAP56-interacting factor {ECO:0000313|Ensembl:ENSP00000417742}; Flags: Fragment;"]
[84261,"'FBXW9'",298,371,306,325,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0070545///PeBoW complex+++GO:0005829///cytosol","GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0000209///protein polyubiquitination+++GO:0043687///post-translational protein modification","F-box and WD repeat domain containing 9","[FBXW9_HUMAN|Reviewed]RecName: Full=F-box/WD repeat-containing protein 9; AltName: Full=F-box and WD-40 domain-containing protein 9;+++[A0A024R7F0_HUMAN|Unreviewed]SubName: Full=F-box and WD-40 domain protein 9, isoform CRA_a {ECO:0000313|EMBL:EAW84297.1};+++[K7EL01_HUMAN|Unreviewed]SubName: Full=F-box/WD repeat-containing protein 9 {ECO:0000313|Ensembl:ENSP00000465854};"]
[84280,"'BTBD10'",514,491,409,471.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0044342///type B pancreatic cell proliferation+++GO:0042327///positive regulation of phosphorylation+++GO:1901215///negative regulation of neuron death","BTB domain containing 10","[BTBDA_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein 10; AltName: Full=Glucose metabolism-related protein 1 {ECO:0000303|PubMed:21267538};+++[B7Z503_HUMAN|Unreviewed]SubName: Full=BTB (POZ) domain containing 10, isoform CRA_c {ECO:0000313|EMBL:EAW68500.1}; SubName: Full=cDNA FLJ58599, highly similar to BTB/POZ domain-containing protein 10 {ECO:0000313|EMBL:BAH12739.1};+++[D3DQW7_HUMAN|Unreviewed]SubName: Full=BTB (POZ) domain containing 10, isoform CRA_a {ECO:0000313|EMBL:EAW68499.1}; SubName: Full=GMRP1 {ECO:0000313|EMBL:AAL69061.2};+++[E9PKM7_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000431572}; Flags: Fragment;+++[E9PKU9_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000435303};+++[E9PN21_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000434857};+++[E9PPD8_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000434579}; Flags: Fragment;+++[Q6P5W1_HUMAN|Unreviewed]SubName: Full=BTBD10 protein {ECO:0000313|EMBL:AAH62633.1}; Flags: Fragment;+++[Q7L2U6_HUMAN|Unreviewed]SubName: Full=BTBD10 protein {ECO:0000313|EMBL:AAH17072.2}; Flags: Fragment;"]
[84292,"'WDR83'",111,102,109,107.333333333333,"00511///Other glycan degradation+++04142///Lysosome","H00422///Glycoproteinoses+++H00139///alpha-Mannosidosis",null,"R08718///G00595 + H2O <=> G00971 + D-Mannose+++R08717///G00309 + H2O <=> G00319 + D-Mannose","GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0071013///catalytic step 2 spliceosome","GO:0005515///protein binding+++GO:0016301///kinase activity","GO:0016310///phosphorylation+++GO:0006397///mRNA processing+++GO:0000165///MAPK cascade+++GO:0008380///RNA splicing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome","WD repeat domain 83","[WDR83_HUMAN|Reviewed]RecName: Full=WD repeat domain-containing protein 83; AltName: Full=Mitogen-activated protein kinase organizer 1; Short=MAPK organizer 1;+++[F8VSE4_HUMAN|Unreviewed]SubName: Full=WD repeat domain-containing protein 83 {ECO:0000313|Ensembl:ENSP00000448331};+++[G3V221_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase organizer 1, isoform CRA_c {ECO:0000313|EMBL:EAW84284.1}; SubName: Full=WD repeat domain-containing protein 83 {ECO:0000313|Ensembl:ENSP00000450416};+++[H0YIE8_HUMAN|Unreviewed]SubName: Full=WD repeat domain-containing protein 83 {ECO:0000313|Ensembl:ENSP00000449257}; Flags: Fragment;+++[H7C0S9_HUMAN|Unreviewed]SubName: Full=WD repeat domain-containing protein 83 {ECO:0000313|Ensembl:ENSP00000396530}; Flags: Fragment;"]
[843,"'CASP10'",15.98,7.29,18.9,14.0566666666667,"04668///TNF signaling pathway+++05152///Tuberculosis+++04622///RIG-I-like receptor signaling pathway+++05161///Hepatitis B+++04210///Apoptosis","H00108///Autoimmune lymphoproliferative syndromes (ALPS)",null,null,"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031265///CD95 death-inducing signaling complex+++GO:0097342///ripoptosome","GO:0008234///cysteine-type peptidase activity+++GO:0005515///protein binding+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0004197///cysteine-type endopeptidase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0016787///hydrolase activity+++GO:0035877///death effector domain binding+++GO:0008233///peptidase activity+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006915///apoptotic process+++GO:0097190///apoptotic signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097194///execution phase of apoptosis+++GO:0007166///cell surface receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0006508///proteolysis","caspase 10","[CASPA_HUMAN|Reviewed]RecName: Full=Caspase-10; Short=CASP-10; EC=3.4.22.63; AltName: Full=Apoptotic protease Mch-4; AltName: Full=FAS-associated death domain protein interleukin-1B-converting enzyme 2; Short=FLICE2; AltName: Full=ICE-like apoptotic protease 4; Contains: RecName: Full=Caspase-10 subunit p23/17; Contains: RecName: Full=Caspase-10 subunit p12; Flags: Precursor;+++[A0A0S2Z3G5_HUMAN|Unreviewed]SubName: Full=Caspase 10 apoptosis-related cysteine peptidase isoform 3 {ECO:0000313|EMBL:ALQ33418.1}; SubName: Full=Caspase 10, apoptosis-related cysteine peptidase, isoform CRA_d {ECO:0000313|EMBL:EAW70250.1}; Flags: Fragment;+++[A0A0S2Z3Z5_HUMAN|Unreviewed]SubName: Full=Caspase 10 apoptosis-related cysteine peptidase isoform 1 {ECO:0000313|EMBL:ALQ33417.1}; Flags: Fragment;+++[B4E3T5_HUMAN|Unreviewed]SubName: Full=Caspase-10 {ECO:0000313|Ensembl:ENSP00000401914}; SubName: Full=cDNA FLJ61090, highly similar to Caspase-10 {ECO:0000313|EMBL:BAG65597.1};"]
[84327,"'ZBED3'",93,90,118,100.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0016055///Wnt signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0001933///negative regulation of protein phosphorylation+++GO:0050821///protein stabilization","zinc finger BED-type containing 3","[ZBED3_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 3; AltName: Full=Axin-interacting protein;+++[D6RIC4_HUMAN|Unreviewed]SubName: Full=Zinc finger BED domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000427487}; Flags: Fragment;+++[Q53EL5_HUMAN|Unreviewed]SubName: Full=Zinc finger, BED domain containing 3 variant {ECO:0000313|EMBL:BAD97344.1}; SubName: Full=Zinc finger, BED-type containing 3, isoform CRA_a {ECO:0000313|EMBL:EAW95790.1}; Flags: Fragment;"]
[84335,"'AKT1S1'",3709,4330,3866,3968.33333333333,"04714///Thermogenesis+++04140///Autophagy - animal+++04211///Longevity regulating pathway+++04152///AMPK signaling pathway+++04213///Longevity regulating pathway - multiple species+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0031931///TORC1 complex+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0038202///TORC1 signaling+++GO:0043523///regulation of neuron apoptotic process+++GO:0032007///negative regulation of TOR signaling+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0006469///negative regulation of protein kinase activity+++GO:0042981///regulation of apoptotic process+++GO:1900034///regulation of cellular response to heat+++GO:0045792///negative regulation of cell size","AKT1 substrate 1","[AKTS1_HUMAN|Reviewed]RecName: Full=Proline-rich AKT1 substrate 1; AltName: Full=40 kDa proline-rich AKT substrate;+++[A0A024QZF6_HUMAN|Unreviewed]SubName: Full=AKT1 substrate 1 (Proline-rich), isoform CRA_a {ECO:0000313|EMBL:EAW52571.1};+++[H9KV91_HUMAN|Unreviewed]SubName: Full=Proline-rich AKT1 substrate 1 {ECO:0000313|Ensembl:ENSP00000375706}; Flags: Fragment;+++[M0R2V8_HUMAN|Unreviewed]SubName: Full=Proline-rich AKT1 substrate 1 {ECO:0000313|Ensembl:ENSP00000472839}; Flags: Fragment;"]
[84439,"'HHIPL1'",619,560,775,651.333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0003824///catalytic activity+++GO:0005044///scavenger receptor activity+++GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0006898///receptor-mediated endocytosis","HHIP like 1","[HIPL1_HUMAN|Reviewed]RecName: Full=HHIP-like protein 1; Flags: Precursor;+++[F1T0G2_HUMAN|Unreviewed]SubName: Full=HHIP-like protein 1 {ECO:0000313|EMBL:BAJ84036.1};+++[F1T0G3_HUMAN|Unreviewed]SubName: Full=HHIP-like protein 1 {ECO:0000313|EMBL:BAJ84037.1};"]
[84448,"'ABLIM2'",27,26,29,27.3333333333333,"04360///Axon guidance",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0030036///actin cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0006351///transcription, DNA-templated+++GO:0030032///lamellipodium assembly","actin binding LIM protein family member 2","[ABLM2_HUMAN|Reviewed]RecName: Full=Actin-binding LIM protein 2; Short=abLIM-2; AltName: Full=Actin-binding LIM protein family member 2;+++[A0A140VK02_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 35a {ECO:0000313|EMBL:AEE61139.1};+++[D6RAL0_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 2 {ECO:0000313|Ensembl:ENSP00000421718}; Flags: Fragment;+++[F5GYR0_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 2 {ECO:0000313|Ensembl:ENSP00000441255};+++[Q19VH1_HUMAN|Unreviewed]SubName: Full=Actin-binding LIM protein 2 splice variant 1 {ECO:0000313|EMBL:ABD83329.1};+++[Q4W5G4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABLIM2 {ECO:0000313|EMBL:AAY40931.1}; Flags: Fragment;"]
[84502,"'JPH4'",0,1,0,0.333333333333333,null,"H01243///Huntington's disease-like syndrome+++H00832///Core neuroacanthocytosis syndromes+++H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0043198///dendritic shaft+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0030314///junctional membrane complex+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005790///smooth endoplasmic reticulum","GO:0015278///calcium-release channel activity","GO:0060402///calcium ion transport into cytosol+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0001817///regulation of cytokine production+++GO:0007612///learning+++GO:0050885///neuromuscular process controlling balance+++GO:0048167///regulation of synaptic plasticity+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:2001256///regulation of store-operated calcium entry","junctophilin 4","[JPH4_HUMAN|Reviewed]RecName: Full=Junctophilin-4; Short=JP-4; AltName: Full=Junctophilin-like 1 protein;+++[A0A087WWT0_HUMAN|Unreviewed]SubName: Full=Junctophilin-4 {ECO:0000313|Ensembl:ENSP00000480477};+++[F5H1L9_HUMAN|Unreviewed]SubName: Full=Junctophilin-4 {ECO:0000313|Ensembl:ENSP00000439562};"]
[8452,"'CUL3'",890,692,798,793.333333333333,"04340///Hedgehog signaling pathway+++04120///Ubiquitin mediated proteolysis+++04341///Hedgehog signaling pathway - fly",null,"M00384///Cul3-SPOP complex",null,"GO:0005634///nucleus+++GO:0036126///sperm flagellum+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031514///motile cilium+++GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005654///nucleoplasm+++GO:0042995///cell projection+++GO:0000139///Golgi membrane+++GO:0005929///cilium+++GO:0005794///Golgi apparatus+++GO:0005827///polar microtubule","GO:0005112///Notch binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0030332///cyclin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031208///POZ domain binding","GO:0016192///vesicle-mediated transport+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0001701///in utero embryonic development+++GO:0040016///embryonic cleavage+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0007369///gastrulation+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0044346///fibroblast apoptotic process+++GO:0000902///cell morphogenesis+++GO:0001831///trophectodermal cellular morphogenesis+++GO:0031648///protein destabilization+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0071630///nuclear protein quality control by the ubiquitin-proteasome system+++GO:0072576///liver morphogenesis+++GO:0007080///mitotic metaphase plate congression+++GO:0017145///stem cell division+++GO:0006513///protein monoubiquitination+++GO:0007050///cell cycle arrest+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016477///cell migration+++GO:0043687///post-translational protein modification+++GO:0031398///positive regulation of protein ubiquitination+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination+++GO:0016055///Wnt signaling pathway+++GO:0000278///mitotic cell cycle+++GO:0030030///cell projection organization+++GO:0000165///MAPK cascade+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0032467///positive regulation of cytokinesis+++GO:0043149///stress fiber assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048208///COPII vesicle coating+++GO:0008284///positive regulation of cell proliferation+++GO:0007229///integrin-mediated signaling pathway","cullin 3","[CUL3_HUMAN|Reviewed]RecName: Full=Cullin-3; Short=CUL-3;+++[A0A024R475_HUMAN|Unreviewed]SubName: Full=Cullin 3, isoform CRA_a {ECO:0000313|EMBL:EAW70830.1};+++[A0A087WTG3_HUMAN|Unreviewed]SubName: Full=Cullin-3 {ECO:0000313|Ensembl:ENSP00000477851};+++[A0A087X1R9_HUMAN|Unreviewed]SubName: Full=Cullin-3 {ECO:0000313|Ensembl:ENSP00000484410}; Flags: Fragment;+++[B7Z600_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53180, highly similar to Cullin-3 {ECO:0000313|EMBL:BAH13086.1};+++[H7C1J0_HUMAN|Unreviewed]SubName: Full=Cullin-3 {ECO:0000313|Ensembl:ENSP00000400558}; Flags: Fragment;+++[H7C1L6_HUMAN|Unreviewed]SubName: Full=Cullin-3 {ECO:0000313|Ensembl:ENSP00000400935}; Flags: Fragment;+++[H7C399_HUMAN|Unreviewed]SubName: Full=Cullin-3 {ECO:0000313|Ensembl:ENSP00000410575}; Flags: Fragment;+++[Q53RD1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CUL3 {ECO:0000313|EMBL:AAY24157.1}; Flags: Fragment;+++[Q53S54_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CUL3 {ECO:0000313|EMBL:AAX93287.1}; Flags: Fragment;"]
[84561,"'SLC12A8'",310.02,385,319,338.006666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005623///cell","GO:0015379///potassium:chloride symporter activity+++GO:0015293///symporter activity","GO:0006813///potassium ion transport+++GO:0006884///cell volume homeostasis+++GO:1990573///potassium ion import across plasma membrane+++GO:0055085///transmembrane transport+++GO:0055064///chloride ion homeostasis+++GO:1902476///chloride transmembrane transport+++GO:0055075///potassium ion homeostasis+++GO:0006811///ion transport","solute carrier family 12 member 8","[S12A8_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 8; AltName: Full=Cation-chloride cotransporter 9;+++[C9IZN2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 8 {ECO:0000313|Ensembl:ENSP00000418636}; Flags: Fragment;+++[H7C5B1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 8 {ECO:0000313|Ensembl:ENSP00000419424}; Flags: Fragment;+++[H7C5L2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 8 {ECO:0000313|Ensembl:ENSP00000420197}; Flags: Fragment;+++[L8ECK3_HUMAN|Unreviewed]SubName: Full=Alternative protein SLC12A8 {ECO:0000313|EMBL:CCQ43717.1};"]
[84626,"'KRBA1'",263,239,286,262.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0008150///biological_process","KRAB-A domain containing 1","[KRBA1_HUMAN|Reviewed]RecName: Full=Protein KRBA1;+++[A0A087WVC5_HUMAN|Unreviewed]SubName: Full=Protein KRBA1 {ECO:0000313|Ensembl:ENSP00000479341}; Flags: Fragment;+++[A0A0C4DH65_HUMAN|Unreviewed]SubName: Full=Protein KRBA1 {ECO:0000313|Ensembl:ENSP00000418647};+++[C9J5U6_HUMAN|Unreviewed]SubName: Full=Protein KRBA1 {ECO:0000313|Ensembl:ENSP00000417921}; Flags: Fragment;+++[C9JYG0_HUMAN|Unreviewed]SubName: Full=Protein KRBA1 {ECO:0000313|Ensembl:ENSP00000419900}; Flags: Fragment;+++[H7C530_HUMAN|Unreviewed]SubName: Full=Protein KRBA1 {ECO:0000313|Ensembl:ENSP00000418841}; Flags: Fragment;"]
[84645,"'C22orf23'",8,12,11,10.3333333333333,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","chromosome 22 open reading frame 23","[EVG1_HUMAN|Reviewed]RecName: Full=UPF0193 protein EVG1;+++[A0A024R1K6_HUMAN|Unreviewed]SubName: Full=Chromosome 22 open reading frame 23, isoform CRA_a {ECO:0000313|EMBL:EAW60201.1};+++[A0A087X0J6_HUMAN|Unreviewed]SubName: Full=UPF0193 protein EVG1 {ECO:0000313|Ensembl:ENSP00000483445};+++[B0QYM1_HUMAN|Unreviewed]SubName: Full=UPF0193 protein EVG1 {ECO:0000313|Ensembl:ENSP00000395077}; Flags: Fragment;+++[B0QYM2_HUMAN|Unreviewed]SubName: Full=UPF0193 protein EVG1 {ECO:0000313|Ensembl:ENSP00000407707}; Flags: Fragment;"]
[84687,"'PPP1R9B'",2574,2499,2278,2450.33333333333,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0045202///synapse+++GO:0044327///dendritic spine head+++GO:0030175///filopodium+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0043197///dendritic spine+++GO:1990780///cytoplasmic side of dendritic spine plasma membrane+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0030054///cell junction+++GO:0000164///protein phosphatase type 1 complex+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0044326///dendritic spine neck+++GO:0015629///actin cytoskeleton+++GO:0005912///adherens junction+++GO:0030864///cortical actin cytoskeleton+++GO:0032591///dendritic spine membrane+++GO:0005654///nucleoplasm+++GO:0043005///neuron projection+++GO:0014069///postsynaptic density+++GO:0032587///ruffle membrane","GO:0003779///actin binding+++GO:0008157///protein phosphatase 1 binding+++GO:0019900///kinase binding+++GO:0044325///ion channel binding+++GO:0051015///actin filament binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0008022///protein C-terminus binding+++GO:0031749///D2 dopamine receptor binding+++GO:0004672///protein kinase activity","GO:0021987///cerebral cortex development+++GO:0046847///filopodium assembly+++GO:0006468///protein phosphorylation+++GO:0007015///actin filament organization+++GO:1990778///protein localization to cell periphery+++GO:1904372///positive regulation of protein localization to actin cortical patch+++GO:1904373///response to kainic acid+++GO:0021766///hippocampus development+++GO:0035902///response to immobilization stress+++GO:1903119///protein localization to actin cytoskeleton+++GO:0042493///response to drug+++GO:0007612///learning+++GO:0014070///response to organic cyclic compound+++GO:0001975///response to amphetamine+++GO:0071392///cellular response to estradiol stimulus+++GO:0007399///nervous system development+++GO:0060179///male mating behavior+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:2000474///regulation of opioid receptor signaling pathway+++GO:0010243///response to organonitrogen compound+++GO:1903829///positive regulation of cellular protein localization+++GO:0048545///response to steroid hormone+++GO:0034695///response to prostaglandin E+++GO:0042127///regulation of cell proliferation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0001932///regulation of protein phosphorylation+++GO:0071315///cellular response to morphine+++GO:0008380///RNA splicing+++GO:0007275///multicellular organism development+++GO:1901653///cellular response to peptide+++GO:0003006///developmental process involved in reproduction+++GO:0030154///cell differentiation+++GO:1904386///response to L-phenylalanine derivative+++GO:0061458///reproductive system development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0007050///cell cycle arrest+++GO:0007568///aging+++GO:0043200///response to amino acid+++GO:0035094///response to nicotine+++GO:0019722///calcium-mediated signaling+++GO:0031175///neuron projection development+++GO:0001560///regulation of cell growth by extracellular stimulus+++GO:0030042///actin filament depolymerization+++GO:0097338///response to clozapine+++GO:0007096///regulation of exit from mitosis+++GO:0035690///cellular response to drug+++GO:0030308///negative regulation of cell growth+++GO:0032355///response to estradiol+++GO:0016358///dendrite development+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0071407///cellular response to organic cyclic compound+++GO:0016477///cell migration","protein phosphatase 1 regulatory subunit 9B","[NEB2_HUMAN|Reviewed]RecName: Full=Neurabin-2; AltName: Full=Neurabin-II; AltName: Full=Protein phosphatase 1 regulatory subunit 9B; AltName: Full=Spinophilin;+++[D3DTX6_HUMAN|Unreviewed]SubName: Full=Neurabin-2 {ECO:0000313|Ensembl:ENSP00000478767}; SubName: Full=Protein phosphatase 1, regulatory subunit 9B, spinophilin, isoform CRA_b {ECO:0000313|EMBL:EAW94638.1};+++[Q96B17_HUMAN|Unreviewed]SubName: Full=PPP1R9B protein {ECO:0000313|EMBL:AAH16162.1}; Flags: Fragment;+++[Q96HI8_HUMAN|Unreviewed]SubName: Full=PPP1R9B protein {ECO:0000313|EMBL:AAH08564.1}; Flags: Fragment;"]
[84707,"'BEX2'",254,324,306,294.666666666667,{"$nulls":4},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0001102///RNA polymerase II activating transcription factor binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042981///regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006915///apoptotic process+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0051726///regulation of cell cycle","brain expressed X-linked 2","[BEX2_HUMAN|Reviewed]RecName: Full=Protein BEX2; AltName: Full=Brain-expressed X-linked protein 2; Short=hBex2;+++[X6RDN0_HUMAN|Unreviewed]SubName: Full=Protein BEX2 {ECO:0000313|Ensembl:ENSP00000394915}; Flags: Fragment;"]
[84759,"'PCGF1'",128,155,165,149.333333333333,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:1990841///promoter-specific chromatin binding+++GO:0008022///protein C-terminus binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0035518///histone H2A monoubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0006342///chromatin silencing","polycomb group ring finger 1","[PCGF1_HUMAN|Reviewed]RecName: Full=Polycomb group RING finger protein 1; AltName: Full=Nervous system Polycomb-1; Short=NSPc1; AltName: Full=RING finger protein 68;"]
[84804,"'MFSD9'",135,121,112,122.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005215///transporter activity","GO:0055085///transmembrane transport","major facilitator superfamily domain containing 9","[MFSD9_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 9;+++[B4DKY6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57151 {ECO:0000313|EMBL:BAG59348.1};+++[F2Z2A2_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000392605};+++[F8WDV5_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000414870};+++[F8WE00_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000402411};+++[H7C3S7_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000413641}; Flags: Fragment;"]
[84808,"'PERM1'",2,2,1,1.66666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm",null,"GO:0014850///response to muscle activity+++GO:0006355///regulation of transcription, DNA-templated","PPARGC1 and ESRR induced regulator, muscle 1","[PERM1_HUMAN|Reviewed]RecName: Full=PGC-1 and ERR-induced regulator in muscle protein 1; AltName: Full=PPARGC1 and ESRR-induced regulator in muscle 1; AltName: Full=Peroxisome proliferator-activated receptor gamma coactivator 1 and estrogen-related receptor-induced regulator in muscle 1;"]
[84838,"'ZNF496'",572,521,534,542.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 496","[ZN496_HUMAN|Reviewed]RecName: Full=Zinc finger protein 496; AltName: Full=Zinc finger protein with KRAB and SCAN domains 17;+++[A0A024R5Q5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 496, isoform CRA_b {ECO:0000313|EMBL:EAW77180.1};+++[A0A0C4DGR5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 496 {ECO:0000313|Ensembl:ENSP00000473324}; Flags: Fragment;"]
[84872,"'ZC3H10'",160,197,177,178,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0035198///miRNA binding+++GO:0046872///metal ion binding","GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0010608///posttranscriptional regulation of gene expression+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA","zinc finger CCCH-type containing 10","[ZC3HA_HUMAN|Reviewed]RecName: Full=Zinc finger CCCH domain-containing protein 10;+++[F8VQT2_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000450122}; Flags: Fragment;+++[F8VSG0_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000448309}; Flags: Fragment;+++[F8VYY3_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000448881}; Flags: Fragment;"]
[84895,"'MIGA2'",411,390,385,395.333333333333,"04146///Peroxisome",null,null,"R02396///Acetyl-CoA:carnitine O-acetyltransferase Acetyl-CoA + Carnitine <=> CoA + O-Acetylcarnitine","GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0060348///bone development+++GO:0008053///mitochondrial fusion","mitoguardin 2","[MIGA2_HUMAN|Reviewed]RecName: Full=Mitoguardin 2 {ECO:0000303|PubMed:26711011}; AltName: Full=Protein FAM73B {ECO:0000305};+++[A0A024R8B3_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 73, member B, isoform CRA_e {ECO:0000313|EMBL:EAW87866.1};+++[B0QZG3_HUMAN|Unreviewed]SubName: Full=Mitoguardin 2 {ECO:0000313|Ensembl:ENSP00000409348}; Flags: Fragment;+++[B4DZP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61502 {ECO:0000313|EMBL:BAG64160.1};+++[H7C474_HUMAN|Unreviewed]SubName: Full=Mitoguardin 2 {ECO:0000313|Ensembl:ENSP00000415906}; Flags: Fragment;"]
[84912,"'SLC35B4'",309,283,328,306.666666666667,{"$nulls":4},"GO:0030173///integral component of Golgi membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus","GO:0005464///UDP-xylose transmembrane transporter activity+++GO:0005462///UDP-N-acetylglucosamine transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046964///3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity+++GO:0005457///GDP-fucose transmembrane transporter activity","GO:1990569///UDP-N-acetylglucosamine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0015790///UDP-xylose transmembrane transport+++GO:0015783///GDP-fucose transmembrane transport+++GO:1902559///3'-phospho-5'-adenylyl sulfate transmembrane transport+++GO:0006111///regulation of gluconeogenesis+++GO:0008643///carbohydrate transport","solute carrier family 35 member B4","[S35B4_HUMAN|Reviewed]RecName: Full=UDP-xylose and UDP-N-acetylglucosamine transporter; AltName: Full=Solute carrier family 35 member B4; AltName: Full=YEA4 homolog;+++[A0A024R779_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35, member B4, isoform CRA_a {ECO:0000313|EMBL:EAW83811.1};+++[F8WAW0_HUMAN|Unreviewed]SubName: Full=UDP-xylose and UDP-N-acetylglucosamine transporter {ECO:0000313|Ensembl:ENSP00000405445};"]
[84930,"'MASTL'",102,95,84,93.6666666666667,null,"H00978///Thrombocytopenia (THC)",null,null,"GO:0032154///cleavage furrow+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton","GO:0051721///protein phosphatase 2A binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007147///female meiosis II+++GO:0051301///cell division+++GO:0018105///peptidyl-serine phosphorylation+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0016310///phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","microtubule associated serine/threonine kinase like","[GWL_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase greatwall; Short=GW; Short=GWL; Short=hGWL; EC=2.7.11.1; AltName: Full=Microtubule-associated serine/threonine-protein kinase-like; Short=MAST-L;+++[A0A087WUU7_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase greatwall {ECO:0000313|Ensembl:ENSP00000478938}; Flags: Fragment;"]
[84946,"'LTV1'",186,189,143,172.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0031902///late endosome membrane+++GO:0030688///preribosome, small subunit precursor+++GO:0005829///cytosol+++GO:0034448///EGO complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0000056///ribosomal small subunit export from nucleus+++GO:0042274///ribosomal small subunit biogenesis","LTV1 ribosome biogenesis factor","[LTV1_HUMAN|Reviewed]RecName: Full=Protein LTV1 homolog;"]
[84968,"'PNMA6A'",145,162,159,155.333333333333,{"$nulls":5},"GO:0005515///protein binding",null,"PNMA family member 6A","[PNM6A_HUMAN|Reviewed]RecName: Full=Paraneoplastic antigen-like protein 6A {ECO:0000305};"]
[8499,"'PPFIA2'",9,1,4,4.66666666666667,"00640///Propanoate metabolism+++04140///Autophagy - animal+++04137///Mitophagy - animal+++01100///Metabolic pathways",null,null,"R00926///Propionyladenylate:CoA propionyltransferase Propionyladenylate + CoA <=> AMP + Propanoyl-CoA+++R01354///ATP:propanoate adenylyltransferase ATP + Propanoate <=> Diphosphate + Propionyladenylate+++R00925///Propanoate:CoA ligase (AMP-forming) ATP + Propanoate + CoA <=> AMP + Diphosphate + Propanoyl-CoA","GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0048786///presynaptic active zone+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding+++GO:0099181///structural constituent of presynapse","GO:0007160///cell-matrix adhesion+++GO:0099172///presynapse organization+++GO:2000300///regulation of synaptic vesicle exocytosis","PTPRF interacting protein alpha 2","[LIPA2_HUMAN|Reviewed]RecName: Full=Liprin-alpha-2; AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2; Short=PTPRF-interacting protein alpha-2;+++[B7Z7Y5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59641, highly similar to Liprin-alpha-2 {ECO:0000313|EMBL:BAH13771.1};+++[F8VU88_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447918}; Flags: Fragment;+++[F8VWG6_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449821};+++[F8VWR9_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449469}; Flags: Fragment;+++[F8VYK7_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000448941}; Flags: Fragment;+++[F8W1Y8_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447792}; Flags: Fragment;+++[G3V200_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449558};+++[H0YH95_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000446555}; Flags: Fragment;+++[H0YHJ4_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447189}; Flags: Fragment;+++[H0YHK3_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447273};+++[H0YIJ4_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449524}; Flags: Fragment;+++[Q4LE62_HUMAN|Unreviewed]SubName: Full=PPFIA2 variant protein {ECO:0000313|EMBL:BAE06091.1}; Flags: Fragment;"]
[8504,"'PEX3'",183,143,165,163.666666666667,"04146///Peroxisome","H01342///Zellweger syndrome (ZS)+++H00205///Peroxisome biogenesis disorder",null,null,"GO:0032994///protein-lipid complex+++GO:0005778///peroxisomal membrane+++GO:0016021///integral component of membrane+++GO:0005777///peroxisome+++GO:0005779///integral component of peroxisomal membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0016020///membrane","GO:0046983///protein dimerization activity+++GO:0008289///lipid binding+++GO:0005515///protein binding","GO:0007031///peroxisome organization+++GO:0045046///protein import into peroxisome membrane+++GO:0055085///transmembrane transport+++GO:0016557///peroxisome membrane biogenesis","peroxisomal biogenesis factor 3","[PEX3_HUMAN|Reviewed]RecName: Full=Peroxisomal biogenesis factor 3; AltName: Full=Peroxin-3; AltName: Full=Peroxisomal assembly protein PEX3;+++[Q7Z6V3_HUMAN|Unreviewed]SubName: Full=Peroxisomal biogenesis factor 3 {ECO:0000313|Ensembl:ENSP00000356564}; Flags: Fragment;"]
[8519,"'IFITM1'",90.02,150.23,86.15,108.8,"04662///B cell receptor signaling pathway","H00506///Osteogenesis imperfecta",null,null,"GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0045669///positive regulation of osteoblast differentiation+++GO:0002376///immune system process+++GO:0008285///negative regulation of cell proliferation+++GO:0001503///ossification+++GO:0051607///defense response to virus+++GO:0050776///regulation of immune response+++GO:0045071///negative regulation of viral genome replication+++GO:0035456///response to interferon-beta+++GO:0035455///response to interferon-alpha+++GO:0009615///response to virus+++GO:0007166///cell surface receptor signaling pathway+++GO:0046597///negative regulation of viral entry into host cell+++GO:0034341///response to interferon-gamma+++GO:0030336///negative regulation of cell migration+++GO:0060337///type I interferon signaling pathway+++GO:0045087///innate immune response","interferon induced transmembrane protein 1","[IFM1_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 1; AltName: Full=Dispanin subfamily A member 2a; Short=DSPA2a; AltName: Full=Interferon-induced protein 17; AltName: Full=Interferon-inducible protein 9-27; AltName: Full=Leu-13 antigen; AltName: CD_antigen=CD225;+++[A0A024R210_HUMAN|Unreviewed]SubName: Full=Interferon induced transmembrane protein 1 (9-27), isoform CRA_a {ECO:0000313|EMBL:EAW61219.1};"]
[85352,"'SHISAL1'",291,231,303,275,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"shisa like 1","[SHSL1_HUMAN|Reviewed]RecName: Full=Protein shisa-like-1 {ECO:0000312|HGNC:HGNC:29335}; Flags: Precursor;"]
[85376,"'RIMBP3'",1.68,4,10,5.22666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0002177///manchette+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0030156///benzodiazepine receptor binding","GO:0007286///spermatid development+++GO:0009566///fertilization+++GO:0030154///cell differentiation+++GO:0007283///spermatogenesis+++GO:0007274///neuromuscular synaptic transmission","RIMS binding protein 3","[RIM3A_HUMAN|Reviewed]RecName: Full=RIMS-binding protein 3A; Short=RIM-BP3.A; AltName: Full=RIMS-binding protein 3.1; Short=RIM-BP3.1;"]
[8544,"'PIR'",72,47,100,73,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0051213///dioxygenase activity+++GO:0005515///protein binding+++GO:0003712///transcription coregulator activity+++GO:0008127///quercetin 2,3-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity","GO:0030224///monocyte differentiation+++GO:0055114///oxidation-reduction process+++GO:0006366///transcription by RNA polymerase II+++GO:1903506///regulation of nucleic acid-templated transcription+++GO:0030099///myeloid cell differentiation+++GO:0007586///digestion","pirin","[PIR_HUMAN|Reviewed]RecName: Full=Pirin; EC=1.13.11.24; AltName: Full=Probable quercetin 2,3-dioxygenase PIR; Short=Probable quercetinase;+++[A0A024RBX6_HUMAN|Unreviewed]SubName: Full=Pirin (Iron-binding nuclear protein), isoform CRA_a {ECO:0000313|EMBL:EAW98887.1};"]
[85450,"'ITPRIP'",753,693,829,758.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"inositol 1,4,5-trisphosphate receptor interacting protein","[IPRI_HUMAN|Reviewed]RecName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein; AltName: Full=Protein DANGER; Flags: Precursor;+++[X6RK76_HUMAN|Unreviewed]SubName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein {ECO:0000313|Ensembl:ENSP00000414141}; Flags: Fragment;"]
[85474,"'LBX2'",17,9,13,13,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","ladybird homeobox 2","[LBX2_HUMAN|Reviewed]RecName: Full=Transcription factor LBX2; AltName: Full=Ladybird homeobox protein homolog 2;+++[G3V218_HUMAN|Unreviewed]SubName: Full=HCG1641699, isoform CRA_b {ECO:0000313|EMBL:EAW99637.1}; SubName: Full=Transcription factor LBX2 {ECO:0000313|Ensembl:ENSP00000450229};"]
[8569,"'MKNK1'",650.76,611.01,648,636.59,"04910///Insulin signaling pathway+++04010///MAPK signaling pathway+++04066///HIF-1 signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0009931///calcium-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity","GO:0006417///regulation of translation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006468///protein phosphorylation","MAP kinase interacting serine/threonine kinase 1","[MKNK1_HUMAN|Reviewed]RecName: Full=MAP kinase-interacting serine/threonine-protein kinase 1; EC=2.7.11.1 {ECO:0000269|PubMed:11463832, ECO:0000269|PubMed:9155018}; AltName: Full=MAP kinase signal-integrating kinase 1; Short=MAPK signal-integrating kinase 1; Short=Mnk1;+++[A8K341_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77058, highly similar to Homo sapiens MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83145.1};+++[B5BU64_HUMAN|Unreviewed]SubName: Full=MAP kinase interacting serine/threonine kinase 1 {ECO:0000313|EMBL:BAG70114.1};+++[B5BUJ6_HUMAN|Unreviewed]SubName: Full=MAP kinase interacting serine/threonine kinase 1 {ECO:0000313|EMBL:BAG70246.1}; Flags: Fragment;+++[E9PIA0_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000436709}; Flags: Fragment;+++[E9PII5_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000431985}; Flags: Fragment;+++[E9PLE7_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000435163}; Flags: Fragment;+++[E9PMM8_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000433038};+++[E9PN34_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000434834};+++[E9PQ23_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000432369};+++[E9PQ26_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000434493};+++[E9PSC9_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000434051};+++[E9PSE0_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000434021}; Flags: Fragment;+++[H0YE67_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000435069}; Flags: Fragment;+++[Q7Z319_HUMAN|Unreviewed]SubName: Full=MAP kinase-interacting serine/threonine-protein kinase 1 {ECO:0000313|Ensembl:ENSP00000339573};"]
[8577,"'TMEFF1'",136.87,163.47,127.13,142.49,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0007275///multicellular organism development","transmembrane protein with EGF like and two follistatin like domains 1","[TEFF1_HUMAN|Reviewed]RecName: Full=Tomoregulin-1; Short=TR-1; AltName: Full=H7365; AltName: Full=Transmembrane protein with EGF-like and one follistatin-like domain; Flags: Precursor;"]
[8602,"'NOP14'",761.01,781,730,757.336666666667,{"$nulls":4},"GO:0030692///Noc4p-Nop14p complex+++GO:0005730///nucleolus+++GO:0030686///90S preribosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0032040///small-subunit processome","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:0019899///enzyme binding","GO:0042274///ribosomal small subunit biogenesis+++GO:0000472///endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","NOP14 nucleolar protein","[NOP14_HUMAN|Reviewed]RecName: Full=Nucleolar protein 14; AltName: Full=Nucleolar complex protein 14;+++[A8KA74_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76065 {ECO:0000313|EMBL:BAF85628.1};+++[E9PFK5_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 14 {ECO:0000313|Ensembl:ENSP00000427415};+++[Q96GC8_HUMAN|Unreviewed]SubName: Full=NOP14 protein {ECO:0000313|EMBL:AAH09760.2}; Flags: Fragment;"]
[8629,"'JRK'",273,241,323,279,{"$nulls":4},"GO:1990904///ribonucleoprotein complex+++GO:0005575///cellular_component+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003729///mRNA binding","GO:0090263///positive regulation of canonical Wnt signaling pathway","Jrk helix-turn-helix protein","[JERKY_HUMAN|Reviewed]RecName: Full=Jerky protein homolog {ECO:0000305};+++[A0A087WZD9_HUMAN|Unreviewed]SubName: Full=Jerky protein homolog {ECO:0000313|Ensembl:ENSP00000482585}; Flags: Fragment;+++[L0R881_HUMAN|Unreviewed]SubName: Full=Alternative protein JRK {ECO:0000313|EMBL:CCO13751.1};+++[O75566_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein JH8 {ECO:0000313|EMBL:AAC32354.1}; Flags: Fragment;"]
[864,"'RUNX3'",0,1,2,1,"04658///Th1 and Th2 cell differentiation",{"$nulls":3},"GO:0005634///nucleus+++GO:0016513///core-binding factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0000790///nuclear chromatin+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005730///nucleolus+++GO:0005829///cytosol","GO:0003677///DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0045786///negative regulation of cell cycle+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0071559///response to transforming growth factor beta+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0048935///peripheral nervous system neuron development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0030182///neuron differentiation+++GO:0006468///protein phosphorylation+++GO:0030097///hemopoiesis+++GO:0006366///transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","runt related transcription factor 3","[RUNX3_HUMAN|Reviewed]RecName: Full=Runt-related transcription factor 3; AltName: Full=Acute myeloid leukemia 2 protein; AltName: Full=Core-binding factor subunit alpha-3; Short=CBF-alpha-3; AltName: Full=Oncogene AML-2; AltName: Full=Polyomavirus enhancer-binding protein 2 alpha C subunit; Short=PEA2-alpha C; Short=PEBP2-alpha C; AltName: Full=SL3-3 enhancer factor 1 alpha C subunit; AltName: Full=SL3/AKV core-binding factor alpha C subunit;+++[A0A024RAH4_HUMAN|Unreviewed]RecName: Full=Runt-related transcription factor {ECO:0000256|PIRNR:PIRNR009374};+++[O14814_HUMAN|Unreviewed]SubName: Full=Transcription factor AML2 {ECO:0000313|EMBL:AAB80759.2}; Flags: Fragment;+++[Q9Y3R8_HUMAN|Unreviewed]SubName: Full=Core binding factor alpha 3 subunit {ECO:0000313|EMBL:CAB42882.1}; Flags: Fragment;"]
[8664,"'EIF3D'",3135,3311,3082,3176,"03013///RNA transport",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m+++GO:0005829///cytosol","GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0098808///mRNA cap binding","GO:0002191///cap-dependent translational initiation+++GO:0006413///translational initiation+++GO:0045727///positive regulation of translation+++GO:0006412///translation+++GO:0075525///viral translational termination-reinitiation+++GO:0002183///cytoplasmic translational initiation+++GO:1902416///positive regulation of mRNA binding+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0075522///IRES-dependent viral translational initiation","eukaryotic translation initiation factor 3 subunit D","[EIF3D_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit D {ECO:0000255|HAMAP-Rule:MF_03003}; Short=eIF3d {ECO:0000255|HAMAP-Rule:MF_03003}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 7 {ECO:0000255|HAMAP-Rule:MF_03003}; AltName: Full=eIF-3-zeta {ECO:0000255|HAMAP-Rule:MF_03003}; AltName: Full=eIF3 p66;+++[A0A0D9SGB5_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit D {ECO:0000313|Ensembl:ENSP00000487325}; Flags: Fragment;+++[B0QYA4_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit D {ECO:0000313|Ensembl:ENSP00000391061}; Flags: Fragment;+++[B0QYA5_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit D {ECO:0000313|Ensembl:ENSP00000390438}; Flags: Fragment;+++[B0QYA6_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit D {ECO:0000313|Ensembl:ENSP00000403584}; Flags: Fragment;+++[B0QYA8_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit D {ECO:0000313|Ensembl:ENSP00000385212}; Flags: Fragment;+++[B4E1K8_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit D {ECO:0000256|HAMAP-Rule:MF_03003}; Short=eIF3d {ECO:0000256|HAMAP-Rule:MF_03003}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 7 {ECO:0000256|HAMAP-Rule:MF_03003}; AltName: Full=eIF-3-zeta {ECO:0000256|HAMAP-Rule:MF_03003};"]
[8676,"'STX11'",31,42,24,32.3333333333333,"04130///SNARE interactions in vesicular transport","H00109///Familial hemophagocytic lymphohistiocytosis (FHPL)",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0005794///Golgi apparatus+++GO:0048787///presynaptic active zone membrane+++GO:0042734///presynaptic membrane+++GO:0005886///plasma membrane+++GO:0031201///SNARE complex","GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0005484///SNAP receptor activity","GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0006906///vesicle fusion+++GO:0016192///vesicle-mediated transport+++GO:0061025///membrane fusion+++GO:0048278///vesicle docking+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane","syntaxin 11","[STX11_HUMAN|Reviewed]RecName: Full=Syntaxin-11;"]
[8706,"'B3GALNT1'",209,182,160,183.666666666667,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++01100///Metabolic pathways",null,"M00068///Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer","R05962///UDP-N-acetyl-D-galactosamine + Globotriaosylceramide <=> UDP + Globoside+++R11321///UDP-N-acetyl-D-galactosamine + iGb3-Cer <=> UDP + iGb4-Cer+++R11378///UDP-N-acetyl-D-galactosamine + Paragloboside <=> UDP + PX2+++R11379///UDP-N-acetyl-D-galactosamine + IV4-alpha-Gal-Gb4Cer <=> UDP + NORint","GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0047273///galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity","GO:0006687///glycosphingolipid metabolic process+++GO:0009312///oligosaccharide biosynthetic process+++GO:0006486///protein glycosylation+++GO:0006487///protein N-linked glycosylation","beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)","[B3GL1_HUMAN|Reviewed]RecName: Full=UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; Short=Beta-1,3-GalNAc-T1; EC=2.4.1.79 {ECO:0000269|PubMed:10993897}; AltName: Full=Beta-1,3-galactosyltransferase 3; Short=Beta-1,3-GalTase 3; Short=Beta3Gal-T3; Short=Beta3GalT3; Short=b3Gal-T3; AltName: Full=Beta-3-Gx-T3; AltName: Full=Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; AltName: Full=Globoside synthase; AltName: Full=UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase;+++[B3KTQ4_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[C9J0F8_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[C9J6I7_HUMAN|Unreviewed]SubName: Full=UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 {ECO:0000313|Ensembl:ENSP00000417053}; Flags: Fragment;+++[C9J8U7_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[C9JD16_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[C9JRV6_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[C9JXR0_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[E7EVF0_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[E7EVS2_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[Q49AT3_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[Q7L9G8_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[Q8TDY1_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[R4X5Z0_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[R4X5Z4_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[R4X601_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};+++[R4X604_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};"]
[8722,"'CTSF'",2914,3397,2731,3014,"04142///Lysosome+++04210///Apoptosis","H00149///Neuronal ceroid lipofuscinosis (NCL)",null,null,"GO:0043202///lysosomal lumen+++GO:0005764///lysosome+++GO:1903561///extracellular vesicle+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome","GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008234///cysteine-type peptidase activity","GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0006508///proteolysis","cathepsin F","[CATF_HUMAN|Reviewed]RecName: Full=Cathepsin F; Short=CATSF; EC=3.4.22.41; Flags: Precursor;+++[A0A024R5G9_HUMAN|Unreviewed]SubName: Full=Cathepsin F, isoform CRA_a {ECO:0000313|EMBL:EAW74548.1};+++[E9PSC2_HUMAN|Unreviewed]SubName: Full=Cathepsin F {ECO:0000313|Ensembl:ENSP00000435822}; Flags: Fragment;+++[H0YD65_HUMAN|Unreviewed]SubName: Full=Cathepsin F {ECO:0000313|Ensembl:ENSP00000433082}; Flags: Fragment;+++[H0YE42_HUMAN|Unreviewed]SubName: Full=Cathepsin F {ECO:0000313|Ensembl:ENSP00000434936}; Flags: Fragment;+++[Q6FHS1_HUMAN|Unreviewed]SubName: Full=CTSF protein {ECO:0000313|EMBL:CAG46481.1}; Flags: Fragment;"]
[8741,"'TNFSF13'",185,214.44,276,225.146666666667,"04672///Intestinal immune network for IgA production+++04060///Cytokine-cytokine receptor interaction+++05323///Rheumatoid arthritis",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0006955///immune response+++GO:0002376///immune system process+++GO:0010469///regulation of signaling receptor activity+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0008284///positive regulation of cell proliferation+++GO:0007165///signal transduction+++GO:0043488///regulation of mRNA stability+++GO:0033209///tumor necrosis factor-mediated signaling pathway","TNF superfamily member 13","[TNF13_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 13; AltName: Full=A proliferation-inducing ligand; Short=APRIL; AltName: Full=TNF- and APOL-related leukocyte expressed ligand 2; Short=TALL-2; AltName: Full=TNF-related death ligand 1; Short=TRDL-1; AltName: CD_antigen=CD256; Flags: Precursor;+++[A0A0U5EM56_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 7B {ECO:0000313|EMBL:CTQ86091.1};+++[A5Y848_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 13 epsilon {ECO:0000313|EMBL:ABQ88322.1};+++[B3KR02_HUMAN|Unreviewed]SubName: Full=HCG2045906, isoform CRA_c {ECO:0000313|EMBL:EAW90175.1}; SubName: Full=cDNA FLJ33379 fis, clone BRACE2006397, highly similar to Tumor necrosis factor ligand superfamily member 13 {ECO:0000313|EMBL:BAG52214.1};+++[C9JF68_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 13 {ECO:0000313|Ensembl:ENSP00000410094}; Flags: Fragment;+++[C9JFN2_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 13 {ECO:0000313|Ensembl:ENSP00000390771}; Flags: Fragment;+++[K7EJ28_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 13 {ECO:0000313|Ensembl:ENSP00000464998};+++[Q2QBA2_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor (Ligand) superfamily member 13 transcript variant delta {ECO:0000313|EMBL:ABA39072.1}; SubName: Full=Tumor necrosis factor ligand superfamily member 13 {ECO:0000313|Ensembl:ENSP00000369908};+++[Q6FGN4_HUMAN|Unreviewed]SubName: Full=HCG2045906, isoform CRA_d {ECO:0000313|EMBL:EAW90176.1}; SubName: Full=TNFSF13 protein {ECO:0000313|EMBL:CAG46870.1}; SubName: Full=Tumor necrosis factor (Ligand) superfamily, member 13 {ECO:0000313|EMBL:ABK41890.1}; Flags: Fragment;+++[Q6FGR7_HUMAN|Unreviewed]SubName: Full=TNFSF13 protein {ECO:0000313|EMBL:CAG46837.1};"]
[8766,"'RAB11A'",1433,1431,1183,1349,"04144///Endocytosis+++04972///Pancreatic secretion+++04961///Endocrine and other factor-regulated calcium reabsorption+++04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0005768///endosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0098837///postsynaptic recycling endosome+++GO:0000922///spindle pole+++GO:0005802///trans-Golgi network+++GO:0030424///axon+++GO:0043231///intracellular membrane-bounded organelle+++GO:0030133///transport vesicle+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005828///kinetochore microtubule+++GO:0045335///phagocytic vesicle+++GO:0032154///cleavage furrow+++GO:0098978///glutamatergic synapse+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0005771///multivesicular body+++GO:0031982///vesicle+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0032991///protein-containing complex+++GO:0055037///recycling endosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0031489///myosin V binding+++GO:0019905///syntaxin binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0008017///microtubule binding+++GO:0000166///nucleotide binding","GO:0032465///regulation of cytokinesis+++GO:0003091///renal water homeostasis+++GO:0006886///intracellular protein transport+++GO:0031175///neuron projection development+++GO:0043687///post-translational protein modification+++GO:0045773///positive regulation of axon extension+++GO:0051650///establishment of vesicle localization+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0090307///mitotic spindle assembly+++GO:0060627///regulation of vesicle-mediated transport+++GO:0010634///positive regulation of epithelial cell migration+++GO:0007080///mitotic metaphase plate congression+++GO:0007049///cell cycle+++GO:0032482///Rab protein signal transduction+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0051223///regulation of protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0099003///vesicle-mediated transport in synapse+++GO:0015031///protein transport+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0010796///regulation of multivesicular body size+++GO:0072594///establishment of protein localization to organelle+++GO:1990182///exosomal secretion+++GO:0090150///establishment of protein localization to membrane+++GO:0016192///vesicle-mediated transport+++GO:0036258///multivesicular body assembly+++GO:0032402///melanosome transport+++GO:0006887///exocytosis+++GO:0030953///astral microtubule organization+++GO:0048227///plasma membrane to endosome transport","RAB11A, member RAS oncogene family","[RB11A_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-11A; Short=Rab-11; AltName: Full=YL8; Flags: Precursor;+++[A0A024R5Z8_HUMAN|Unreviewed]SubName: Full=RAB11A, member RAS oncogene family, isoform CRA_a {ECO:0000313|EMBL:EAW77753.1};+++[B4DQU5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57160, highly similar to Ras-related protein Rab-11A {ECO:0000313|EMBL:BAG61057.1};+++[H3BMH2_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-11A {ECO:0000313|Ensembl:ENSP00000454381}; Flags: Fragment;+++[H3BN38_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-11A {ECO:0000313|Ensembl:ENSP00000454673}; Flags: Fragment;+++[H3BSC1_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-11A {ECO:0000313|Ensembl:ENSP00000456638};"]
[8789,"'FBP2'",6,22,38,22,"01110///Biosynthesis of secondary metabolites+++00680///Methane metabolism+++00030///Pentose phosphate pathway+++01100///Metabolic pathways+++04152///AMPK signaling pathway+++01130///Biosynthesis of antibiotics+++04910///Insulin signaling pathway+++00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01120///Microbial metabolism in diverse environments+++00710///Carbon fixation in photosynthetic organisms+++00051///Fructose and mannose metabolism","H00114///Fructose-1,6-bisphosphatase deficiency","M00167///Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P+++M00003///Gluconeogenesis, oxaloacetate => fructose-6P+++M00165///Reductive pentose phosphate cycle (Calvin cycle)+++M00344///Formaldehyde assimilation, xylulose monophosphate pathway","R00762///D-Fructose-1,6-bisphosphate 1-phosphohydrolase   D-Fructose 1,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate+++R04780///beta-D-Fructose 1,6-bisphosphate 1-phosphohydrolase   beta-D-Fructose 1,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate","GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0030018///Z disc+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0005654///nucleoplasm","GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0042132///fructose 1,6-bisphosphate 1-phosphatase activity","GO:0006000///fructose metabolic process+++GO:0006094///gluconeogenesis+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0005986///sucrose biosynthetic process","fructose-bisphosphatase 2","[F16P2_HUMAN|Reviewed]RecName: Full=Fructose-1,6-bisphosphatase isozyme 2; Short=FBPase 2; EC=3.1.3.11; AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; AltName: Full=Muscle FBPase;"]
[8808,"'IL1RL2'",0,1,0,0.333333333333333,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0004908///interleukin-1 receptor activity+++GO:0004909///interleukin-1, type I, activating receptor activity","GO:0045087///innate immune response+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0050727///regulation of inflammatory response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006968///cellular defense response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0006954///inflammatory response+++GO:0071345///cellular response to cytokine stimulus+++GO:0045582///positive regulation of T cell differentiation","interleukin 1 receptor like 2","[ILRL2_HUMAN|Reviewed]RecName: Full=Interleukin-1 receptor-like 2; AltName: Full=IL-36 receptor; Short=IL-36R; AltName: Full=Interleukin-1 receptor-related protein 2; Short=IL-1Rrp2; Short=IL1R-rp2; Flags: Precursor;+++[C9K0I8_HUMAN|Unreviewed]SubName: Full=Interleukin-1 receptor-like 2 {ECO:0000313|Ensembl:ENSP00000387611}; Flags: Fragment;"]
[8825,"'LIN7A'",71,72,99,80.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005923///bicellular tight junction+++GO:0005886///plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0043005///neuron projection+++GO:0005911///cell-cell junction+++GO:0016323///basolateral plasma membrane+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0098793///presynapse","GO:0097016///L27 domain binding+++GO:0005515///protein binding","GO:0006887///exocytosis+++GO:0048489///synaptic vesicle transport+++GO:0015031///protein transport+++GO:0007269///neurotransmitter secretion+++GO:1903361///protein localization to basolateral plasma membrane+++GO:0065003///protein-containing complex assembly+++GO:0048839///inner ear development","lin-7 homolog A, crumbs cell polarity complex component","[LIN7A_HUMAN|Reviewed]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=hLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Tax interaction protein 33; Short=TIP-33; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[H0YI92_HUMAN|Unreviewed]SubName: Full=Protein lin-7 homolog A {ECO:0000313|Ensembl:ENSP00000448891}; Flags: Fragment;+++[H0YIA8_HUMAN|Unreviewed]SubName: Full=Protein lin-7 homolog A {ECO:0000313|Ensembl:ENSP00000448975}; Flags: Fragment;+++[J3KN23_HUMAN|Unreviewed]SubName: Full=Protein lin-7 homolog A {ECO:0000313|Ensembl:ENSP00000261203};"]
[88455,"'ANKRD13A'",1716,1448,1374,1512.66666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0005770///late endosome",null,null,"ankyrin repeat domain 13A","[AN13A_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 13A; AltName: Full=Protein KE03;+++[F8W150_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 13A {ECO:0000313|Ensembl:ENSP00000447110}; Flags: Fragment;+++[H0YIN8_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 13A {ECO:0000313|Ensembl:ENSP00000449781}; Flags: Fragment;+++[Q3ZTS7_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain 13, isoform CRA_b {ECO:0000313|EMBL:EAW97892.1}; SubName: Full=NY-REN-25 antigen {ECO:0000313|EMBL:AAQ76810.1};+++[Q9Y5A3_HUMAN|Unreviewed]SubName: Full=NY-REN-25 antigen {ECO:0000313|EMBL:AAD42869.1}; Flags: Fragment;+++[S4R3D2_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 13A {ECO:0000313|Ensembl:ENSP00000474172};+++[S4R3U2_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 13A {ECO:0000313|Ensembl:ENSP00000474745}; Flags: Fragment;"]
[8864,"'PER2'",31,37,20,29.3333333333333,"04713///Circadian entrainment+++04710///Circadian rhythm+++05221///Acute myeloid leukemia+++04711///Circadian rhythm - fly+++05202///Transcriptional misregulation in cancer+++05168///Herpes simplex infection","H00688///Familial advanced sleep phase syndrome",null,null,"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0001222///transcription corepressor binding+++GO:0003713///transcription coactivator activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding","GO:0050872///white fat cell differentiation+++GO:0019229///regulation of vasoconstriction+++GO:0070345///negative regulation of fat cell proliferation+++GO:0009416///response to light stimulus+++GO:0005978///glycogen biosynthetic process+++GO:0097167///circadian regulation of translation+++GO:0042752///regulation of circadian rhythm+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0006631///fatty acid metabolic process+++GO:0007623///circadian rhythm+++GO:0019249///lactate biosynthetic process+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0031397///negative regulation of protein ubiquitination+++GO:0051946///regulation of glutamate uptake involved in transmission of nerve impulse+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048511///rhythmic process+++GO:0032922///circadian regulation of gene expression+++GO:0002931///response to ischemia+++GO:0070932///histone H3 deacetylation+++GO:0050796///regulation of insulin secretion+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0042754///negative regulation of circadian rhythm+++GO:0050767///regulation of neurogenesis+++GO:0006094///gluconeogenesis+++GO:0051726///regulation of cell cycle+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription","period circadian regulator 2","[PER2_HUMAN|Reviewed]RecName: Full=Period circadian protein homolog 2; Short=hPER2; AltName: Full=Circadian clock protein PERIOD 2;+++[E9PD89_HUMAN|Unreviewed]SubName: Full=Period circadian protein homolog 2 {ECO:0000313|Ensembl:ENSP00000405891}; Flags: Fragment;+++[L8E8R3_HUMAN|Unreviewed]SubName: Full=Alternative protein PER2 {ECO:0000313|EMBL:CCQ43695.1};"]
[8887,"'TAX1BP1'",2774,2251,2614,2546.33333333333,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0019900///kinase binding","GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0032480///negative regulation of type I interferon production+++GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","Tax1 binding protein 1","[TAXB1_HUMAN|Reviewed]RecName: Full=Tax1-binding protein 1; AltName: Full=TRAF6-binding protein;+++[B4DSG5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56149, highly similar to Tax1-binding protein 1 {ECO:0000313|EMBL:BAG61627.1};+++[B8ZZD4_HUMAN|Unreviewed]SubName: Full=Tax1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000386515};+++[C9J7J4_HUMAN|Unreviewed]SubName: Full=Tax1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000411490}; Flags: Fragment;+++[C9JBZ7_HUMAN|Unreviewed]SubName: Full=Tax1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000395290}; Flags: Fragment;+++[F8WBU9_HUMAN|Unreviewed]SubName: Full=Tax1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000391215};+++[H7C3L5_HUMAN|Unreviewed]SubName: Full=Tax1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000412575}; Flags: Fragment;+++[L8E7U3_HUMAN|Unreviewed]SubName: Full=Alternative protein TAX1BP1 {ECO:0000313|EMBL:CCQ43345.1};+++[V9GZ06_HUMAN|Unreviewed]SubName: Full=Tax1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000477282}; Flags: Fragment;"]
[890,"'CCNA2'",252,209,205,222,"05169///Epstein-Barr virus infection+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation+++04152///AMPK signaling pathway+++05203///Viral carcinogenesis+++05165///Human papillomavirus infection+++05161///Hepatitis B+++04218///Cellular senescence",null,"M00693///Cell cycle - G2/M transition",null,"GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0097124///cyclin A2-CDK2 complex+++GO:0001940///male pronucleus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0001939///female pronucleus+++GO:0005829///cytosol","GO:0004672///protein kinase activity+++GO:0019904///protein domain specific binding+++GO:0097472///cyclin-dependent protein kinase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity","GO:0071732///cellular response to nitric oxide+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0090102///cochlea development+++GO:0008284///positive regulation of cell proliferation+++GO:0016572///histone phosphorylation+++GO:0033762///response to glucagon+++GO:0007265///Ras protein signal transduction+++GO:0071407///cellular response to organic cyclic compound+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032355///response to estradiol+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0006275///regulation of DNA replication+++GO:0071373///cellular response to luteinizing hormone stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071314///cellular response to cocaine+++GO:0016032///viral process+++GO:0044320///cellular response to leptin stimulus+++GO:0031100///animal organ regeneration+++GO:0007049///cell cycle+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:0051301///cell division+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division+++GO:0000278///mitotic cell cycle+++GO:0044843///cell cycle G1/S phase transition+++GO:0045787///positive regulation of cell cycle+++GO:0016579///protein deubiquitination+++GO:0071392///cellular response to estradiol stimulus","cyclin A2","[CCNA2_HUMAN|Reviewed]RecName: Full=Cyclin-A2 {ECO:0000312|HGNC:HGNC:1578}; Short=Cyclin-A {ECO:0000303|PubMed:1967822}; AltName: Full=Cyclin A {ECO:0000303|PubMed:1967822};"]
[8905,"'AP1S2'",1632,1372,1381,1461.66666666667,"04142///Lysosome",{"$nulls":3},"GO:0030117///membrane coat+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0000139///Golgi membrane+++GO:0005905///clathrin-coated pit+++GO:0031410///cytoplasmic vesicle+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0050690///regulation of defense response to virus by virus+++GO:0015031///protein transport+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","adaptor related protein complex 1 subunit sigma 2","[AP1S2_HUMAN|Reviewed]RecName: Full=AP-1 complex subunit sigma-2; AltName: Full=Adaptor protein complex AP-1 subunit sigma-1B; AltName: Full=Adaptor-related protein complex 1 subunit sigma-1B; AltName: Full=Clathrin assembly protein complex 1 sigma-1B small chain; AltName: Full=Golgi adaptor HA1/AP1 adaptin sigma-1B subunit; AltName: Full=Sigma 1B subunit of AP-1 clathrin; AltName: Full=Sigma-adaptin 1B; AltName: Full=Sigma1B-adaptin;+++[A0A024RBX8_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[A6NH01_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[B7Z3M9_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[F6SFB5_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[H0Y673_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588}; Flags: Fragment;+++[H7BZG6_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588}; Flags: Fragment;+++[Q549M9_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};"]
[8940,"'TOP3B'",538,570,580,562.666666666667,"03440///Homologous recombination+++03460///Fanconi anemia pathway",null,"M00414///Bloom's syndrome complex",null,"GO:0005634///nucleus+++GO:0000793///condensed chromosome","GO:0003917///DNA topoisomerase type I activity+++GO:0005515///protein binding+++GO:0003916///DNA topoisomerase activity+++GO:0016853///isomerase activity+++GO:0003677///DNA binding+++GO:0003723///RNA binding","GO:0006265///DNA topological change+++GO:0007059///chromosome segregation","DNA topoisomerase III beta","[TOP3B_HUMAN|Reviewed]RecName: Full=DNA topoisomerase 3-beta-1; EC=5.99.1.2; AltName: Full=DNA topoisomerase III beta-1;+++[A0A024R1C2_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092};+++[A8K4N2_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092};+++[C9J9X4_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[C9JEI7_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[C9JEQ1_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[C9JF56_HUMAN|Unreviewed]SubName: Full=DNA topoisomerase 3-beta-1 {ECO:0000313|Ensembl:ENSP00000390824}; Flags: Fragment;+++[C9JHR0_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[C9JKE2_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[C9JT00_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[C9JTQ7_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[F2Z2A5_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092};+++[H0Y6W0_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;+++[H7C4B0_HUMAN|Unreviewed]RecName: Full=DNA topoisomerase {ECO:0000256|RuleBase:RU362092}; EC=5.99.1.2 {ECO:0000256|RuleBase:RU362092}; Flags: Fragment;"]
[89781,"'HPS4'",1083,1026,1095,1068,null,"H00166///Hermansky-Pudlak syndrome (HPS)",null,null,"GO:0016020///membrane+++GO:0042470///melanosome+++GO:0005737///cytoplasm+++GO:0031085///BLOC-3 complex+++GO:0005829///cytosol+++GO:0005764///lysosome+++GO:0031410///cytoplasmic vesicle+++GO:0042827///platelet dense granule","GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0046983///protein dimerization activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017137///Rab GTPase binding","GO:0007599///hemostasis+++GO:0050821///protein stabilization+++GO:0030318///melanocyte differentiation+++GO:1903232///melanosome assembly+++GO:0006605///protein targeting+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0007596///blood coagulation+++GO:0006996///organelle organization+++GO:0007040///lysosome organization+++GO:0048075///positive regulation of eye pigmentation","HPS4, biogenesis of lysosomal organelles complex 3 subunit 2","[HPS4_HUMAN|Reviewed]RecName: Full=Hermansky-Pudlak syndrome 4 protein; AltName: Full=Light-ear protein homolog;+++[A0A024R1I6_HUMAN|Unreviewed]SubName: Full=Hermansky-Pudlak syndrome 4, isoform CRA_a {ECO:0000313|EMBL:EAW59719.1};+++[A8K2E6_HUMAN|Unreviewed]SubName: Full=Hermansky-Pudlak syndrome 4, isoform CRA_b {ECO:0000313|EMBL:EAW59718.1}; SubName: Full=cDNA FLJ77277, highly similar to Homo sapiens Hermansky-Pudlak syndrome 4 (HPS4), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF82900.1};+++[E5RG08_HUMAN|Unreviewed]SubName: Full=Hermansky-Pudlak syndrome 4 protein {ECO:0000313|Ensembl:ENSP00000430291};+++[F1LLU8_HUMAN|Unreviewed]SubName: Full=Hermansky-Pudlak syndrome 4 protein {ECO:0000313|Ensembl:ENSP00000415081}; Flags: Fragment;+++[F8VYA9_HUMAN|Unreviewed]SubName: Full=Hermansky-Pudlak syndrome 4 protein {ECO:0000313|Ensembl:ENSP00000399705};+++[F8WC53_HUMAN|Unreviewed]SubName: Full=Hermansky-Pudlak syndrome 4 protein {ECO:0000313|Ensembl:ENSP00000406764};+++[Q6P1K3_HUMAN|Unreviewed]SubName: Full=Hermansky-Pudlak syndrome 4 {ECO:0000313|EMBL:AAH65030.1};"]
[89796,"'NAV1'",2734,2135,2422,2430.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015630///microtubule cytoskeleton+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0043194///axon initial segment","GO:0005515///protein binding","GO:0001764///neuron migration+++GO:0030154///cell differentiation+++GO:0007399///nervous system development+++GO:0022008///neurogenesis+++GO:0001578///microtubule bundle formation+++GO:0007275///multicellular organism development","neuron navigator 1","[NAV1_HUMAN|Reviewed]RecName: Full=Neuron navigator 1; AltName: Full=Pore membrane and/or filament-interacting-like protein 3; AltName: Full=Steerin-1; AltName: Full=Unc-53 homolog 1; Short=unc53H1;+++[A0A0A0MRJ3_HUMAN|Unreviewed]SubName: Full=Neuron navigator 1 {ECO:0000313|Ensembl:ENSP00000356271};+++[A4FUT7_HUMAN|Unreviewed]SubName: Full=NAV1 protein {ECO:0000313|EMBL:AAI17684.1}; Flags: Fragment;+++[H0Y6F6_HUMAN|Unreviewed]SubName: Full=Neuron navigator 1 {ECO:0000313|Ensembl:ENSP00000405437}; Flags: Fragment;+++[H0YA94_HUMAN|Unreviewed]SubName: Full=Neuron navigator 1 {ECO:0000313|Ensembl:ENSP00000426436}; Flags: Fragment;+++[H7BZD9_HUMAN|Unreviewed]SubName: Full=Neuron navigator 1 {ECO:0000313|Ensembl:ENSP00000389123}; Flags: Fragment;"]
[89858,"'SIGLEC12'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0030246///carbohydrate binding","GO:0007155///cell adhesion","sialic acid binding Ig like lectin 12 (gene/pseudogene)","[SIG12_HUMAN|Reviewed]RecName: Full=Sialic acid-binding Ig-like lectin 12; Short=Siglec-12; AltName: Full=Sialic acid-binding Ig-like lectin-like 1; Short=Siglec-L1; Flags: Precursor;+++[M0QYF3_HUMAN|Unreviewed]SubName: Full=Sialic acid-binding Ig-like lectin 12 {ECO:0000313|Ensembl:ENSP00000469791};"]
[89941,"'RHOT2'",1373,1493,1365,1410.33333333333,"04137///Mitophagy - animal",{"$nulls":3},"GO:0031307///integral component of mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0003924///GTPase activity+++GO:0046872///metal ion binding+++GO:0005525///GTP binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0019725///cellular homeostasis+++GO:0097345///mitochondrial outer membrane permeabilization+++GO:0047497///mitochondrion transport along microtubule+++GO:0010821///regulation of mitochondrion organization+++GO:0007266///Rho protein signal transduction+++GO:0007005///mitochondrion organization+++GO:0051056///regulation of small GTPase mediated signal transduction","ras homolog family member T2","[MIRO2_HUMAN|Reviewed]RecName: Full=Mitochondrial Rho GTPase 2; Short=MIRO-2; Short=hMiro-2; EC=3.6.5.-; AltName: Full=Ras homolog gene family member T2;+++[H3BMP9_HUMAN|Unreviewed]SubName: Full=Mitochondrial Rho GTPase 2 {ECO:0000313|Ensembl:ENSP00000454486};+++[H3BP40_HUMAN|Unreviewed]SubName: Full=Mitochondrial Rho GTPase 2 {ECO:0000313|Ensembl:ENSP00000455138};+++[H3BST5_HUMAN|Unreviewed]SubName: Full=Mitochondrial Rho GTPase 2 {ECO:0000313|Ensembl:ENSP00000456855}; Flags: Fragment;+++[H3BU27_HUMAN|Unreviewed]SubName: Full=Mitochondrial Rho GTPase 2 {ECO:0000313|Ensembl:ENSP00000457437}; Flags: Fragment;+++[H3BUX4_HUMAN|Unreviewed]SubName: Full=Mitochondrial Rho GTPase 2 {ECO:0000313|Ensembl:ENSP00000457852};+++[H3BVI5_HUMAN|Unreviewed]SubName: Full=Mitochondrial Rho GTPase 2 {ECO:0000313|Ensembl:ENSP00000458136};+++[I3L2C6_HUMAN|Unreviewed]SubName: Full=Mitochondrial Rho GTPase 2 {ECO:0000313|Ensembl:ENSP00000459564}; Flags: Fragment;"]
[90,"'ACVR1'",493,427,406,442,"04350///TGF-beta signaling pathway+++04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++05418///Fluid shear stress and atherosclerosis","H00430///Fibrodysplasia ossificans progressiva (FOP)","M00679///BMP signaling",null,"GO:0045177///apical part of cell+++GO:0016020///membrane+++GO:0048179///activin receptor complex+++GO:0043235///receptor complex+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0048185///activin binding+++GO:0005524///ATP binding+++GO:0098821///BMP receptor activity+++GO:0042803///protein homodimerization activity+++GO:0004672///protein kinase activity+++GO:0050431///transforming growth factor beta binding+++GO:0046332///SMAD binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004675///transmembrane receptor protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0019838///growth factor binding+++GO:0017046///peptide hormone binding+++GO:0005025///transforming growth factor beta receptor activity, type I+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0016361///activin receptor activity, type I","GO:0007369///gastrulation+++GO:0002526///acute inflammatory response+++GO:0001707///mesoderm formation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0001701///in utero embryonic development+++GO:0060923///cardiac muscle cell fate commitment+++GO:1905007///positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0032924///activin receptor signaling pathway+++GO:0051145///smooth muscle cell differentiation+++GO:0003183///mitral valve morphogenesis+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0030278///regulation of ossification+++GO:0003143///embryonic heart tube morphogenesis+++GO:0009968///negative regulation of signal transduction+++GO:0061312///BMP signaling pathway involved in heart development+++GO:0001755///neural crest cell migration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0003203///endocardial cushion morphogenesis+++GO:0030509///BMP signaling pathway+++GO:0030501///positive regulation of bone mineralization+++GO:0003289///atrial septum primum morphogenesis+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0007281///germ cell development+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0016310///phosphorylation+++GO:0007498///mesoderm development+++GO:0007507///heart development+++GO:0003274///endocardial cushion fusion+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0060037///pharyngeal system development+++GO:2000017///positive regulation of determination of dorsal identity+++GO:0061445///endocardial cushion cell fate commitment+++GO:0071773///cellular response to BMP stimulus+++GO:0007368///determination of left/right symmetry+++GO:0030335///positive regulation of cell migration+++GO:0003181///atrioventricular valve morphogenesis+++GO:0003148///outflow tract septum morphogenesis+++GO:0001702///gastrulation with mouth forming second+++GO:0060412///ventricular septum morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006468///protein phosphorylation+++GO:0007389///pattern specification process+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0001569///branching involved in blood vessel morphogenesis","activin A receptor type 1","[ACVR1_HUMAN|Reviewed]RecName: Full=Activin receptor type-1; EC=2.7.11.30; AltName: Full=Activin receptor type I; Short=ACTR-I; AltName: Full=Activin receptor-like kinase 2; Short=ALK-2; AltName: Full=Serine/threonine-protein kinase receptor R1; Short=SKR1; AltName: Full=TGF-B superfamily receptor type I; Short=TSR-I; Flags: Precursor;+++[A0A0S2Z2Y3_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109}; Flags: Fragment;+++[A0A0S2Z345_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109}; Flags: Fragment;+++[A0A1B0GXA9_HUMAN|Unreviewed]SubName: Full=Activin receptor type-1 {ECO:0000313|Ensembl:ENSP00000401189}; Flags: Fragment;+++[C9J1R3_HUMAN|Unreviewed]SubName: Full=Activin receptor type-1 {ECO:0000313|Ensembl:ENSP00000400767}; Flags: Fragment;+++[C9JHJ7_HUMAN|Unreviewed]SubName: Full=Activin receptor type-1 {ECO:0000313|Ensembl:ENSP00000403006}; Flags: Fragment;+++[C9JW28_HUMAN|Unreviewed]SubName: Full=Activin receptor type-1 {ECO:0000313|Ensembl:ENSP00000399322}; Flags: Fragment;+++[D3DPA4_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein kinase receptor {ECO:0000256|RuleBase:RU361271}; EC=2.7.11.30 {ECO:0000256|RuleBase:RU361271};+++[F5GY91_HUMAN|Unreviewed]SubName: Full=Activin receptor type-1 {ECO:0000313|Ensembl:ENSP00000440091}; Flags: Fragment;+++[L8E7H6_HUMAN|Unreviewed]SubName: Full=Alternative protein ACVR1 {ECO:0000313|EMBL:CCQ43084.1};+++[Q53SF4_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109}; Flags: Fragment;+++[Q53SV1_HUMAN|Unreviewed]RecName: Full=Receptor protein serine/threonine kinase {ECO:0000256|SAAS:SAAS00410109}; EC=2.7.11.30 {ECO:0000256|SAAS:SAAS00410109}; Flags: Fragment;"]
[90187,"'EMILIN3'",136,151,218,168.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0031012///extracellular matrix","GO:0005201///extracellular matrix structural constituent",null,"elastin microfibril interfacer 3","[EMIL3_HUMAN|Reviewed]RecName: Full=EMILIN-3; AltName: Full=EMILIN-5; AltName: Full=Elastin microfibril interface-located protein 3; Short=Elastin microfibril interfacer 3; AltName: Full=Elastin microfibril interface-located protein 5; Short=Elastin microfibril interfacer 5; Flags: Precursor;"]
[90226,"'UCN2'",9.44,14,6.95,10.13,{"$nulls":4},"GO:0005622///intracellular+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0001664///G protein-coupled receptor binding+++GO:0005179///hormone activity+++GO:0051431///corticotropin-releasing hormone receptor 2 binding+++GO:0042562///hormone binding+++GO:0051429///corticotropin-releasing hormone receptor binding","GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0006950///response to stress+++GO:0009755///hormone-mediated signaling pathway+++GO:0031669///cellular response to nutrient levels+++GO:0007586///digestion","urocortin 2","[UCN2_HUMAN|Reviewed]RecName: Full=Urocortin-2; AltName: Full=Stresscopin-related peptide; AltName: Full=Urocortin II; Short=Ucn II; AltName: Full=Urocortin-related peptide; Flags: Precursor;"]
[90362,"'FAM110B'",240,186,236,220.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005739///mitochondrion",null,null,"family with sequence similarity 110 member B","[F110B_HUMAN|Reviewed]RecName: Full=Protein FAM110B;+++[A0A024R7V5_HUMAN|Unreviewed]SubName: Full=Chromosome 8 open reading frame 72, isoform CRA_a {ECO:0000313|EMBL:EAW86802.1};+++[B3KRT5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34902 fis, clone NT2RI2000588 {ECO:0000313|EMBL:BAG52497.1};"]
[9040,"'UBE2M'",1386,1584,1346,1438.66666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0019788///NEDD8 transferase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding","GO:0043525///positive regulation of neuron apoptotic process+++GO:0006464///cellular protein modification process+++GO:0043687///post-translational protein modification+++GO:0045116///protein neddylation+++GO:0016567///protein ubiquitination","ubiquitin conjugating enzyme E2 M","[UBC12_HUMAN|Reviewed]RecName: Full=NEDD8-conjugating enzyme Ubc12; EC=2.3.2.-; AltName: Full=NEDD8 carrier protein; AltName: Full=Ubiquitin-conjugating enzyme E2 M;+++[A0A024R4T4_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast), isoform CRA_a {ECO:0000313|EMBL:EAW72613.1};+++[M0QX69_HUMAN|Unreviewed]SubName: Full=NEDD8-conjugating enzyme Ubc12 {ECO:0000313|Ensembl:ENSP00000468940}; Flags: Fragment;+++[M0QYI6_HUMAN|Unreviewed]SubName: Full=NEDD8-conjugating enzyme Ubc12 {ECO:0000313|Ensembl:ENSP00000469855}; Flags: Fragment;"]
[90522,"'YIF1B'",1324,1468,1368,1386.66666666667,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0016021///integral component of membrane",null,"GO:0006888///ER to Golgi vesicle-mediated transport","Yip1 interacting factor homolog B, membrane trafficking protein","[YIF1B_HUMAN|Reviewed]RecName: Full=Protein YIF1B; AltName: Full=YIP1-interacting factor homolog B;+++[K7EJQ6_HUMAN|Unreviewed]SubName: Full=Protein YIF1B {ECO:0000313|Ensembl:ENSP00000465277}; Flags: Fragment;+++[K7EPQ7_HUMAN|Unreviewed]SubName: Full=Protein YIF1B {ECO:0000313|Ensembl:ENSP00000467489};+++[K7ERQ0_HUMAN|Unreviewed]SubName: Full=Protein YIF1B {ECO:0000313|Ensembl:ENSP00000468358}; Flags: Fragment;+++[K7ERY2_HUMAN|Unreviewed]SubName: Full=Protein YIF1B {ECO:0000313|Ensembl:ENSP00000468463}; Flags: Fragment;+++[Q9H5F7_HUMAN|Unreviewed]SubName: Full=Hypothetical LOC541469 protein {ECO:0000313|EMBL:EAW56768.1}; SubName: Full=Yip1 interacting factor homolog B (S. cerevisiae) {ECO:0000313|EMBL:AAH25257.1}; SubName: Full=cDNA: FLJ23477 fis, clone HSI15732 {ECO:0000313|EMBL:BAB15669.1};"]
[9055,"'PRC1'",43,41,29,37.6666666666667,{"$nulls":4},"GO:0005876///spindle microtubule+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0070938///contractile ring+++GO:0030496///midbody+++GO:0005874///microtubule+++GO:0000922///spindle pole+++GO:0005819///spindle","GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0008017///microtubule binding","GO:0008284///positive regulation of cell proliferation+++GO:0000022///mitotic spindle elongation+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0000226///microtubule cytoskeleton organization+++GO:0032465///regulation of cytokinesis+++GO:0001578///microtubule bundle formation","protein regulator of cytokinesis 1","[PRC1_HUMAN|Reviewed]RecName: Full=Protein regulator of cytokinesis 1 {ECO:0000312|HGNC:HGNC:9341};+++[A0A024RC67_HUMAN|Unreviewed]SubName: Full=Protein regulator of cytokinesis 1, isoform CRA_e {ECO:0000313|EMBL:EAX02138.1};+++[G3V3N7_HUMAN|Unreviewed]SubName: Full=Protein regulator of cytokinesis 1 {ECO:0000313|Ensembl:ENSP00000451344}; Flags: Fragment;+++[H0YL53_HUMAN|Unreviewed]SubName: Full=Protein regulator of cytokinesis 1 {ECO:0000313|Ensembl:ENSP00000453063}; Flags: Fragment;+++[H0YLA0_HUMAN|Unreviewed]SubName: Full=Protein regulator of cytokinesis 1 {ECO:0000313|Ensembl:ENSP00000453117}; Flags: Fragment;+++[H0YM42_HUMAN|Unreviewed]SubName: Full=Protein regulator of cytokinesis 1 {ECO:0000313|Ensembl:ENSP00000453455}; Flags: Fragment;+++[H0YNE4_HUMAN|Unreviewed]SubName: Full=Protein regulator of cytokinesis 1 {ECO:0000313|Ensembl:ENSP00000453977}; Flags: Fragment;+++[H3BSJ8_HUMAN|Unreviewed]SubName: Full=Protein regulator of cytokinesis 1 {ECO:0000313|Ensembl:ENSP00000456737}; Flags: Fragment;"]
[9069,"'CLDN12'",316,232,277,275,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0071944///cell periphery+++GO:0005923///bicellular tight junction+++GO:0016328///lateral plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005198///structural molecule activity","GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","claudin 12","[CLD12_HUMAN|Reviewed]RecName: Full=Claudin-12;+++[A8MX62_HUMAN|Unreviewed]SubName: Full=Claudin-12 {ECO:0000313|Ensembl:ENSP00000378102}; Flags: Fragment;+++[B2R687_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92839, highly similar to Homo sapiens claudin 12 (CLDN12), mRNA {ECO:0000313|EMBL:BAG35384.1};+++[C9J4P0_HUMAN|Unreviewed]SubName: Full=Claudin-12 {ECO:0000313|Ensembl:ENSP00000391062}; Flags: Fragment;+++[C9J841_HUMAN|Unreviewed]SubName: Full=Claudin-12 {ECO:0000313|Ensembl:ENSP00000411399}; Flags: Fragment;+++[Q6FIF6_HUMAN|Unreviewed]SubName: Full=CLDN12 protein {ECO:0000313|EMBL:CAG38501.1};"]
[90736,"'FAM104B'",161,178,195,178,{"$nulls":7},"family with sequence similarity 104 member B","[F104B_HUMAN|Reviewed]RecName: Full=Protein FAM104B;"]
[90835,"'CCDC189'",109,123,135,122.333333333333,"04020///Calcium signaling pathway+++04922///Glucagon signaling pathway+++04910///Insulin signaling pathway","H01948///Glycogen storage disease type IX+++H01760///Hepatic glycogen storage disease+++H00069///Glycogen storage diseases (GSD)",null,null,"GO:0005964///phosphorylase kinase complex+++GO:0005829///cytosol","GO:0004674///protein serine/threonine kinase activity+++GO:0005516///calmodulin binding+++GO:0019899///enzyme binding+++GO:0004689///phosphorylase kinase activity+++GO:0050321///tau-protein kinase activity+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0006091///generation of precursor metabolites and energy+++GO:0005978///glycogen biosynthetic process+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0005977///glycogen metabolic process+++GO:0018105///peptidyl-serine phosphorylation+++GO:0045819///positive regulation of glycogen catabolic process","coiled-coil domain containing 189","[CC189_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 189;+++[F5H7A8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 189 {ECO:0000313|Ensembl:ENSP00000442648};+++[H0YGC5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 189 {ECO:0000313|Ensembl:ENSP00000442644}; Flags: Fragment;+++[H3BNW1_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 189 {ECO:0000313|Ensembl:ENSP00000455034}; Flags: Fragment;+++[H3BTQ9_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 189 {ECO:0000313|Ensembl:ENSP00000457287};"]
[90957,"'DHX57'",400,328,375,367.666666666667,{"$nulls":4},"GO:0005739///mitochondrion","GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003676///nucleic acid binding","GO:0006396///RNA processing","DExH-box helicase 57","[DHX57_HUMAN|Reviewed]RecName: Full=Putative ATP-dependent RNA helicase DHX57; EC=3.6.4.13; AltName: Full=DEAH box protein 57;+++[A0A087WW12_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase DHX57 {ECO:0000313|Ensembl:ENSP00000479840}; Flags: Fragment;+++[A0A087WZ11_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase DHX57 {ECO:0000313|Ensembl:ENSP00000482275};+++[H7BZ23_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase DHX57 {ECO:0000313|Ensembl:ENSP00000387404}; Flags: Fragment;+++[H7C109_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase DHX57 {ECO:0000313|Ensembl:ENSP00000397841}; Flags: Fragment;+++[L8ECP8_HUMAN|Unreviewed]SubName: Full=Alternative protein DHX57 {ECO:0000313|EMBL:CCQ43942.1};+++[Q8N4U2_HUMAN|Unreviewed]SubName: Full=DHX57 protein {ECO:0000313|EMBL:AAH33636.1}; Flags: Fragment;"]
[91039,"'DPP9'",3264.69,2963.08,3236.74,3154.83666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0004177///aminopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis","dipeptidyl peptidase 9","[DPP9_HUMAN|Reviewed]RecName: Full=Dipeptidyl peptidase 9; Short=DP9; EC=3.4.14.5; AltName: Full=Dipeptidyl peptidase IV-related protein 2; Short=DPRP-2; AltName: Full=Dipeptidyl peptidase IX; Short=DPP IX; AltName: Full=Dipeptidyl peptidase-like protein 9; Short=DPLP9;+++[A0A2R8YF65_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000496196}; Flags: Fragment;+++[M0QXA6_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000469020}; Flags: Fragment;+++[M0QXG6_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000469152}; Flags: Fragment;+++[M0QXI5_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000469187}; Flags: Fragment;+++[M0QXN4_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000469282}; Flags: Fragment;+++[M0QZ97_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000470393};+++[M0R0I1_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000471250}; Flags: Fragment;+++[M0R145_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000471629}; Flags: Fragment;+++[M0R162_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000471659}; Flags: Fragment;+++[M0R1L4_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000471954}; Flags: Fragment;+++[M0R2A8_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000472430};+++[M0R2G6_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000472549}; Flags: Fragment;+++[M0R334_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000472968}; Flags: Fragment;+++[M0R3C4_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000473130}; Flags: Fragment;+++[M0R3E8_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 9 {ECO:0000313|Ensembl:ENSP00000473175}; Flags: Fragment;"]
[91156,"'IGFN1'",1,3,1,1.66666666666667,{"$nulls":4},"GO:0030018///Z disc+++GO:0005737///cytoplasm+++GO:0030017///sarcomere+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0008150///biological_process","immunoglobulin-like and fibronectin type III domain containing 1","[IGFN1_HUMAN|Reviewed]RecName: Full=Immunoglobulin-like and fibronectin type III domain-containing protein 1; AltName: Full=EEF1A2-binding protein 1; AltName: Full=KY-interacting protein 1;+++[H7BZ61_HUMAN|Unreviewed]SubName: Full=Immunoglobulin-like and fibronectin type III domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387975}; Flags: Fragment;"]
[9127,"'P2RX6'",23,37,19,26.3333333333333,"04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0098794///postsynapse+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0005639///integral component of nuclear inner membrane+++GO:0043197///dendritic spine+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0098688///parallel fiber to Purkinje cell synapse+++GO:0005887///integral component of plasma membrane+++GO:0043025///neuronal cell body+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0005886///plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0015267///channel activity+++GO:0005524///ATP binding+++GO:0001614///purinergic nucleotide receptor activity+++GO:0042802///identical protein binding+++GO:0035381///ATP-gated ion channel activity+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity","GO:0007596///blood coagulation+++GO:0006936///muscle contraction+++GO:0051260///protein homooligomerization+++GO:0034220///ion transmembrane transport+++GO:0006812///cation transport+++GO:0098655///cation transmembrane transport+++GO:0006811///ion transport+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0007165///signal transduction+++GO:0033198///response to ATP+++GO:0060079///excitatory postsynaptic potential+++GO:0051291///protein heterooligomerization","purinergic receptor P2X 6","[P2RX6_HUMAN|Reviewed]RecName: Full=P2X purinoceptor 6; Short=P2X6; AltName: Full=ATP receptor; AltName: Full=P2XM; AltName: Full=Purinergic receptor; AltName: Full=Purinergic receptor P2X-like 1;+++[D3DX42_HUMAN|Unreviewed]SubName: Full=Purinergic receptor P2X-like 1, orphan receptor, isoform CRA_b {ECO:0000313|EMBL:EAX02912.1};+++[E7ES48_HUMAN|Unreviewed]SubName: Full=p2X purinoceptor 6 {ECO:0000313|Ensembl:ENSP00000401192};+++[H7C140_HUMAN|Unreviewed]SubName: Full=p2X purinoceptor 6 {ECO:0000313|Ensembl:ENSP00000398347}; Flags: Fragment;+++[H7C266_HUMAN|Unreviewed]SubName: Full=p2X purinoceptor 6 {ECO:0000313|Ensembl:ENSP00000404223}; Flags: Fragment;+++[H7C2V4_HUMAN|Unreviewed]SubName: Full=p2X purinoceptor 6 {ECO:0000313|Ensembl:ENSP00000407920}; Flags: Fragment;+++[Q05BG9_HUMAN|Unreviewed]RecName: Full=P2X purinoceptor {ECO:0000256|RuleBase:RU000681};+++[Q6P1Z3_HUMAN|Unreviewed]SubName: Full=p2RX6 protein {ECO:0000313|EMBL:AAH64805.1};"]
[9136,"'RRP9'",118,151,138,135.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0032040///small-subunit processome+++GO:0005634///nucleus+++GO:0031428///box C/D snoRNP complex+++GO:0005730///nucleolus","GO:0030515///snoRNA binding+++GO:0034511///U3 snoRNA binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing","ribosomal RNA processing 9, U3 small nucleolar RNA binding protein","[U3IP2_HUMAN|Reviewed]RecName: Full=U3 small nucleolar RNA-interacting protein 2; AltName: Full=RRP9 homolog; AltName: Full=U3 small nucleolar ribonucleoprotein-associated 55 kDa protein; Short=U3 snoRNP-associated 55 kDa protein; Short=U3-55K;"]
[9144,"'SYNGR2'",3607,4003,3950,3853.33333333333,"00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01100///Metabolic pathways","H00469///Mitochondrial DNA depletion syndrome (MDS)+++H01118///Progressive external ophthalmoplegia (PEO)",null,"R08233///ATP:5-fluorodeoxyuridine 5'-phosphotransferase 5-Fluorodeoxyuridine + ATP <=> 5-Fluorodeoxyuridine monophosphate + ADP+++R01567///ATP:thymidine 5'-phosphotransferase ATP + Thymidine <=> ADP + dTMP+++R02099///ATP:deoxyuridine 5'-phosphotransferase ATP + Deoxyuridine <=> ADP + dUMP","GO:0030672///synaptic vesicle membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0008021///synaptic vesicle+++GO:0045202///synapse+++GO:0005811///lipid droplet+++GO:0031594///neuromuscular junction+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding","GO:0045055///regulated exocytosis+++GO:0048499///synaptic vesicle membrane organization","synaptogyrin 2","[SNG2_HUMAN|Reviewed]RecName: Full=Synaptogyrin-2 {ECO:0000305}; AltName: Full=Cellugyrin {ECO:0000250|UniProtKB:O54980};+++[A0A024R8T9_HUMAN|Unreviewed]RecName: Full=Synaptogyrin {ECO:0000256|PIRNR:PIRNR011282};+++[K7EJ35_HUMAN|Unreviewed]SubName: Full=Synaptogyrin 2, isoform CRA_a {ECO:0000313|EMBL:EAW89499.1}; SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000465005};+++[K7ELD9_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000466032};+++[K7ELS8_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000466204}; Flags: Fragment;+++[K7ENG9_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000466942};"]
[91543,"'RSAD2'",185,21,27,77.6666666666667,"05164///Influenza A",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP","R00512///ATP:CMP phosphotransferase ATP + CMP <=> ADP + CDP+++R01665///ATP:dCMP phosphotransferase ATP + dCMP <=> ADP + dCDP+++R00158///ATP:UMP phosphotransferase ATP + UMP <=> ADP + UDP","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005741///mitochondrial outer membrane+++GO:0005811///lipid droplet+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0001650///fibrillar center","GO:0051536///iron-sulfur cluster binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0043621///protein self-association+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0003824///catalytic activity","GO:0002376///immune system process+++GO:0035710///CD4-positive, alpha-beta T cell activation+++GO:0016032///viral process+++GO:0050709///negative regulation of protein secretion+++GO:0060337///type I interferon signaling pathway+++GO:0043367///CD4-positive, alpha-beta T cell differentiation+++GO:0045087///innate immune response+++GO:0034157///positive regulation of toll-like receptor 7 signaling pathway+++GO:0009615///response to virus+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:0045071///negative regulation of viral genome replication+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:0051607///defense response to virus","radical S-adenosyl methionine domain containing 2","[RSAD2_HUMAN|Reviewed]RecName: Full=Radical S-adenosyl methionine domain-containing protein 2; AltName: Full=Cytomegalovirus-induced gene 5 protein; AltName: Full=Viperin; AltName: Full=Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible;+++[C9J674_HUMAN|Unreviewed]SubName: Full=Radical S-adenosyl methionine domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000406427}; Flags: Fragment;"]
[91647,"'ATPAF2'",368,377,436,393.666666666667,null,"H01369///ATP synthase deficiency",null,null,"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0016607///nuclear speck","GO:0005515///protein binding","GO:0043461///proton-transporting ATP synthase complex assembly","ATP synthase mitochondrial F1 complex assembly factor 2","[ATPF2_HUMAN|Reviewed]RecName: Full=ATP synthase mitochondrial F1 complex assembly factor 2; AltName: Full=ATP12 homolog; Flags: Precursor;+++[B4DG98_HUMAN|Unreviewed]SubName: Full=ATP synthase mitochondrial F1 complex assembly factor 2, isoform CRA_d {ECO:0000313|EMBL:EAW55679.1}; SubName: Full=cDNA FLJ60490, highly similar to ATP synthase mitochondrial F1 complexassembly factor 2, mitochondrial {ECO:0000313|EMBL:BAG57709.1};+++[C9J2Q2_HUMAN|Unreviewed]SubName: Full=ATP synthase mitochondrial F1 complex assembly factor 2 {ECO:0000313|Ensembl:ENSP00000397198}; Flags: Fragment;+++[J3KTB2_HUMAN|Unreviewed]SubName: Full=ATP synthase mitochondrial F1 complex assembly factor 2, isoform CRA_a {ECO:0000313|EMBL:EAW55676.1};+++[K7ELC1_HUMAN|Unreviewed]SubName: Full=ATP synthase mitochondrial F1 complex assembly factor 2 {ECO:0000313|Ensembl:ENSP00000466008}; Flags: Fragment;"]
[9172,"'MYOM2'",32,54,27,37.6666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0032982///myosin filament+++GO:0030017///sarcomere+++GO:0005865///striated muscle thin filament+++GO:0031430///M band+++GO:0005739///mitochondrion+++GO:0030018///Z disc","GO:0008307///structural constituent of muscle+++GO:0051015///actin filament binding+++GO:0051371///muscle alpha-actinin binding+++GO:0019900///kinase binding+++GO:0005515///protein binding","GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0045214///sarcomere organization+++GO:0048739///cardiac muscle fiber development+++GO:0055003///cardiac myofibril assembly+++GO:0030240///skeletal muscle thin filament assembly+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0006936///muscle contraction+++GO:0002074///extraocular skeletal muscle development","myomesin 2","[MYOM2_HUMAN|Reviewed]RecName: Full=Myomesin-2; AltName: Full=165 kDa connectin-associated protein; AltName: Full=165 kDa titin-associated protein; AltName: Full=M-protein; AltName: Full=Myomesin family member 2;+++[A0A024QZ61_HUMAN|Unreviewed]SubName: Full=Myomesin (M-protein) 2, 165kDa, isoform CRA_c {ECO:0000313|EMBL:EAW51491.1};+++[A0A0J9YVV7_HUMAN|Unreviewed]SubName: Full=Myomesin-2 {ECO:0000313|Ensembl:ENSP00000487697};+++[E7EWH9_HUMAN|Unreviewed]SubName: Full=Myomesin-2 {ECO:0000313|Ensembl:ENSP00000428396};"]
[91807,"'MYLK3'",3,6.86,5.99,5.28333333333333,"04611///Platelet activation+++04971///Gastric acid secretion+++04810///Regulation of actin cytoskeleton+++04921///Oxytocin signaling pathway+++04510///Focal adhesion+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04270///Vascular smooth muscle contraction+++04371///Apelin signaling pathway","H00801///Familial thoracic aortic aneurysm and dissection (TAAD)",null,null,"GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0004687///myosin light chain kinase activity","GO:0002528///regulation of vascular permeability involved in acute inflammatory response+++GO:0048769///sarcomerogenesis+++GO:0055003///cardiac myofibril assembly+++GO:0016310///phosphorylation+++GO:0071347///cellular response to interleukin-1+++GO:0006468///protein phosphorylation+++GO:0060298///positive regulation of sarcomere organization+++GO:0045214///sarcomere organization","myosin light chain kinase 3","[MYLK3_HUMAN|Reviewed]RecName: Full=Myosin light chain kinase 3; EC=2.7.11.18; AltName: Full=Cardiac-MyBP-C-associated Ca/CaM kinase; Short=Cardiac-MLCK;+++[L8E9T3_HUMAN|Unreviewed]SubName: Full=Alternative protein MYLK3 {ECO:0000313|EMBL:CCQ43924.1};"]
[9194,"'SLC16A7'",83.23,44.03,59.97,62.41,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015293///symporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0050833///pyruvate transmembrane transporter activity+++GO:0005477///pyruvate secondary active transmembrane transporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity","GO:0015718///monocarboxylic acid transport+++GO:1901475///pyruvate transmembrane transport+++GO:0035873///lactate transmembrane transport+++GO:0055085///transmembrane transport","solute carrier family 16 member 7","[MOT2_HUMAN|Reviewed]RecName: Full=Monocarboxylate transporter 2; Short=MCT 2; AltName: Full=Solute carrier family 16 member 7;+++[A0A024RBB2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 16 (Monocarboxylic acid transporters), member 7, isoform CRA_a {ECO:0000313|EMBL:EAW97099.1};+++[F8VQS4_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000450133};+++[F8VS95_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000447814}; Flags: Fragment;+++[F8VVU7_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000449229};+++[F8VXG4_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000449972};+++[F8VYZ2_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000448870};+++[F8W0N3_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000446722}; Flags: Fragment;+++[F8W0U4_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000447555};+++[F8W1M4_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 2 {ECO:0000313|Ensembl:ENSP00000447459};"]
[92002,"'CCNQ'",153,223,187,187.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0005515///protein binding","GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006357///regulation of transcription by RNA polymerase II","cyclin Q","[CCNQ_HUMAN|Reviewed]RecName: Full=Cyclin-Q; AltName: Full=CDK10-activating cyclin; AltName: Full=Cyclin-M; AltName: Full=Cyclin-related protein FAM58A;+++[A0A087WUL6_HUMAN|Unreviewed]SubName: Full=Cyclin-Q {ECO:0000313|Ensembl:ENSP00000478747};+++[A0A087WY98_HUMAN|Unreviewed]SubName: Full=Cyclin-Q {ECO:0000313|Ensembl:ENSP00000481634};+++[A0A087X0G9_HUMAN|Unreviewed]SubName: Full=Cyclin-Q {ECO:0000313|Ensembl:ENSP00000483391}; Flags: Fragment;+++[A0A087X1W3_HUMAN|Unreviewed]SubName: Full=Cyclin-Q {ECO:0000313|Ensembl:ENSP00000484506}; Flags: Fragment;+++[D3DWU4_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 58, member A, isoform CRA_a {ECO:0000313|EMBL:EAW72856.1};+++[H7C3N1_HUMAN|Unreviewed]SubName: Full=Cyclin-Q {ECO:0000313|Ensembl:ENSP00000412865}; Flags: Fragment;+++[K7EM37_HUMAN|Unreviewed]SubName: Full=Cyclin-Q {ECO:0000313|Ensembl:ENSP00000466345}; Flags: Fragment;"]
[9215,"'LARGE1'",1416,1391,1377.69,1394.89666666667,"01100///Metabolic pathways+++00515///Mannose type O-glycan biosynthesis","H01960///Muscular dystrophy-dystroglycanopathy type B+++H00590///Congenital muscular dystrophies (CMD/MDC)+++H00120///Muscular dystrophy-dystroglycanopathy type A+++H01962///Congenital muscular dystrophy type 1D (MDC1D)",null,null,"GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane","GO:0015020///glucuronosyltransferase activity+++GO:0042285///xylosyltransferase activity+++GO:0030145///manganese ion binding+++GO:0016740///transferase activity+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0005515///protein binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding+++GO:0035252///UDP-xylosyltransferase activity+++GO:0003824///catalytic activity","GO:0060538///skeletal muscle organ development+++GO:0046716///muscle cell cellular homeostasis+++GO:0006486///protein glycosylation+++GO:0008152///metabolic process+++GO:0035269///protein O-linked mannosylation+++GO:0006688///glycosphingolipid biosynthetic process+++GO:0043403///skeletal muscle tissue regeneration+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006493///protein O-linked glycosylation+++GO:0009101///glycoprotein biosynthetic process","LARGE xylosyl- and glucuronyltransferase 1","[LARG1_HUMAN|Reviewed]RecName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000312|HGNC:HGNC:6511}; EC=2.4.-.-; AltName: Full=Acetylglucosaminyltransferase-like 1A; AltName: Full=Glycosyltransferase-like protein; Includes: RecName: Full=Xylosyltransferase LARGE {ECO:0000305}; EC=2.4.2.- {ECO:0000269|PubMed:22223806}; Includes: RecName: Full=Beta-1,3-glucuronyltransferase LARGE {ECO:0000305}; EC=2.4.1.- {ECO:0000269|PubMed:22223806, ECO:0000269|PubMed:25279697, ECO:0000269|PubMed:25279699};+++[B0QY08_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000403841}; SubName: Full=Like-glycosyltransferase {ECO:0000313|EMBL:CAQ09433.1}; Flags: Fragment;+++[B0QY11_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000476415}; SubName: Full=Like-glycosyltransferase {ECO:0000313|EMBL:CAQ09435.1}; Flags: Fragment;+++[B0QYZ8_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000415546}; Flags: Fragment;+++[B0QYZ9_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000389605}; Flags: Fragment;+++[B0QZ00_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000406000}; Flags: Fragment;+++[B0QZ01_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000411065}; Flags: Fragment;+++[B0QZ02_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000396277}; Flags: Fragment;+++[B7ZB84_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000476866}; SubName: Full=Like-glycosyltransferase {ECO:0000313|EMBL:CAX15214.1}; Flags: Fragment;+++[B7ZB85_HUMAN|Unreviewed]SubName: Full=LARGE xylosyl- and glucuronyltransferase 1 {ECO:0000313|Ensembl:ENSP00000476364}; SubName: Full=Like-glycosyltransferase {ECO:0000313|EMBL:CAX15215.1}; Flags: Fragment;+++[L8ECB5_HUMAN|Unreviewed]SubName: Full=Alternative protein LARGE {ECO:0000313|EMBL:CCQ43277.1};+++[X5D9N1_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like protein isoform D {ECO:0000313|EMBL:AHW56713.1};+++[X5DR28_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like protein isoform A {ECO:0000313|EMBL:AHW56517.1}; SubName: Full=Like-glycosyltransferase, isoform CRA_a {ECO:0000313|EMBL:EAW60041.1}; Flags: Fragment;+++[X5DRG1_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like protein isoform C {ECO:0000313|EMBL:AHW56672.1};+++[X5DRJ7_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like protein isoform B {ECO:0000313|EMBL:AHW56712.1};"]
[9223,"'MAGI1'",1001,696,649,782,"04015///Rap1 signaling pathway+++05165///Human papillomavirus infection+++04530///Tight junction+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005923///bicellular tight junction+++GO:0010494///cytoplasmic stress granule+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0005912///adherens junction+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus+++GO:0005911///cell-cell junction+++GO:0005654///nucleoplasm+++GO:0030054///cell junction+++GO:0005634///nucleus","GO:0003727///single-stranded RNA binding+++GO:0003697///single-stranded DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0042802///identical protein binding+++GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0005524///ATP binding+++GO:0051393///alpha-actinin binding","GO:0007166///cell surface receptor signaling pathway+++GO:0065003///protein-containing complex assembly+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0070997///neuron death+++GO:0007155///cell adhesion+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","membrane associated guanylate kinase, WW and PDZ domain containing 1","[MAGI1_HUMAN|Reviewed]RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1; AltName: Full=Atrophin-1-interacting protein 3; Short=AIP-3; AltName: Full=BAI1-associated protein 1; Short=BAP-1; AltName: Full=Membrane-associated guanylate kinase inverted 1; Short=MAGI-1; AltName: Full=Trinucleotide repeat-containing gene 19 protein; AltName: Full=WW domain-containing protein 3; Short=WWP3;+++[C9J7L9_HUMAN|Unreviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase {ECO:0000256|RuleBase:RU361215}; EC=3.4.19.12 {ECO:0000256|RuleBase:RU361215}; Flags: Fragment;+++[F8WEY5_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase BAP1 {ECO:0000313|Ensembl:ENSP00000419709};+++[H0Y8E8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase BAP1 {ECO:0000313|Ensembl:ENSP00000420647}; Flags: Fragment;+++[H7C4V7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase BAP1 {ECO:0000313|Ensembl:ENSP00000418320}; Flags: Fragment;+++[Q96TC6_HUMAN|Unreviewed]SubName: Full=Cerebral protein-13 {ECO:0000313|EMBL:BAB46926.1}; SubName: Full=Ubiquitin carboxyl-terminal hydrolase BAP1 {ECO:0000313|Ensembl:ENSP00000482839};"]
[92342,"'METTL18'",28,24,23,25,{"$nulls":4},"GO:0032991///protein-containing complex","GO:0031072///heat shock protein binding+++GO:0008168///methyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity","GO:0008150///biological_process+++GO:0032259///methylation","methyltransferase like 18","[MET18_HUMAN|Reviewed]RecName: Full=Histidine protein methyltransferase 1 homolog; EC=2.1.1.-; AltName: Full=Arsenic-transactivated protein 2; Short=AsTP2; AltName: Full=Methyltransferase-like protein 18;+++[A0A024R8Y7_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 156, isoform CRA_a {ECO:0000313|EMBL:EAW90862.1};+++[Q5TI78_HUMAN|Unreviewed]SubName: Full=Histidine protein methyltransferase 1 homolog {ECO:0000313|Ensembl:ENSP00000402305}; Flags: Fragment;"]
[924,"'CD7'",0,1,0,0.333333333333333,"04640///Hematopoietic cell lineage",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0038023///signaling receptor activity","GO:0002376///immune system process+++GO:0006955///immune response+++GO:0002250///adaptive immune response+++GO:0042110///T cell activation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway","CD7 molecule","[CD7_HUMAN|Reviewed]RecName: Full=T-cell antigen CD7; AltName: Full=GP40; AltName: Full=T-cell leukemia antigen; AltName: Full=T-cell surface antigen Leu-9; AltName: Full=TP41; AltName: CD_antigen=CD7; Flags: Precursor;+++[J3QLC7_HUMAN|Unreviewed]SubName: Full=T-cell antigen CD7 {ECO:0000313|Ensembl:ENSP00000463489};+++[J3QLM0_HUMAN|Unreviewed]SubName: Full=T-cell antigen CD7 {ECO:0000313|Ensembl:ENSP00000463612};+++[J3QRF1_HUMAN|Unreviewed]SubName: Full=T-cell antigen CD7 {ECO:0000313|Ensembl:ENSP00000464182}; Flags: Fragment;+++[J3QS65_HUMAN|Unreviewed]SubName: Full=T-cell antigen CD7 {ECO:0000313|Ensembl:ENSP00000464546};+++[J3QS78_HUMAN|Unreviewed]SubName: Full=T-cell antigen CD7 {ECO:0000313|Ensembl:ENSP00000464565};+++[Q29VG3_HUMAN|Unreviewed]SubName: Full=CD7 antigen {ECO:0000313|EMBL:AAY15456.1}; SubName: Full=CD7 antigen (P41), isoform CRA_c {ECO:0000313|EMBL:EAW89765.1};"]
[9244,"'CRLF1'",2038,2477,1590,2035,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0009897///external side of plasma membrane+++GO:0097058///CRLF-CLCF1 complex+++GO:0005615///extracellular space+++GO:0043235///receptor complex","GO:0046982///protein heterodimerization activity+++GO:0005127///ciliary neurotrophic factor receptor binding+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0019955///cytokine binding+++GO:0005125///cytokine activity","GO:0070106///interleukin-27-mediated signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0001657///ureteric bud development+++GO:0010469///regulation of signaling receptor activity+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043524///negative regulation of neuron apoptotic process+++GO:2000672///negative regulation of motor neuron apoptotic process+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein","cytokine receptor like factor 1","[CRLF1_HUMAN|Reviewed]RecName: Full=Cytokine receptor-like factor 1; AltName: Full=Cytokine-like factor 1; Short=CLF-1; AltName: Full=ZcytoR5; Flags: Precursor;+++[M0QZL6_HUMAN|Unreviewed]SubName: Full=Cytokine receptor-like factor 1 {ECO:0000313|Ensembl:ENSP00000470625}; Flags: Fragment;"]
[9265,"'CYTH3'",1336,1224,1236,1265.33333333333,"04144///Endocytosis+++04072///Phospholipase D signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0001726///ruffle+++GO:0030054///cell junction+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005912///adherens junction+++GO:0000139///Golgi membrane+++GO:0005923///bicellular tight junction+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding","GO:0032012///regulation of ARF protein signal transduction+++GO:0090162///establishment of epithelial cell polarity+++GO:0045785///positive regulation of cell adhesion+++GO:0048193///Golgi vesicle transport","cytohesin 3","[CYH3_HUMAN|Reviewed]RecName: Full=Cytohesin-3; AltName: Full=ARF nucleotide-binding site opener 3; Short=Protein ARNO3; AltName: Full=General receptor of phosphoinositides 1; Short=Grp1; AltName: Full=PH, SEC7 and coiled-coil domain-containing protein 3;+++[Q75ML1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSCD3 {ECO:0000313|EMBL:AAS07510.1}; Flags: Fragment;+++[Q96HS5_HUMAN|Unreviewed]SubName: Full=CYTH3 protein {ECO:0000313|EMBL:AAH08191.1};"]
[9270,"'ITGB1BP1'",1100,1111,1104,1105,"04666///Fc gamma R-mediated phagocytosis+++04144///Endocytosis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030027///lamellipodium+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005856///cytoskeleton+++GO:0071944///cell periphery+++GO:0001726///ruffle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005815///microtubule organizing center+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0005178///integrin binding+++GO:0008565///protein transporter activity+++GO:0019900///kinase binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0044877///protein-containing complex binding","GO:0043087///regulation of GTPase activity+++GO:0007219///Notch signaling pathway+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0006933///negative regulation of cell adhesion involved in substrate-bound cell migration+++GO:0051781///positive regulation of cell division+++GO:0007229///integrin-mediated signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006469///negative regulation of protein kinase activity+++GO:0007160///cell-matrix adhesion+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0035148///tube formation+++GO:0001525///angiogenesis+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0032148///activation of protein kinase B activity+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0051451///myoblast migration+++GO:0008284///positive regulation of cell proliferation+++GO:0031214///biomineral tissue development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090315///negative regulation of protein targeting to membrane+++GO:0032091///negative regulation of protein binding+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0007155///cell adhesion+++GO:0033622///integrin activation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0008285///negative regulation of cell proliferation+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0002043///blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0015031///protein transport+++GO:2001044///regulation of integrin-mediated signaling pathway+++GO:0051496///positive regulation of stress fiber assembly+++GO:0010764///negative regulation of fibroblast migration+++GO:0050880///regulation of blood vessel size+++GO:0035556///intracellular signal transduction+++GO:0043113///receptor clustering+++GO:0030154///cell differentiation+++GO:0016477///cell migration+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading","integrin subunit beta 1 binding protein 1","[ITBP1_HUMAN|Reviewed]RecName: Full=Integrin beta-1-binding protein 1; AltName: Full=Integrin cytoplasmic domain-associated protein 1; Short=ICAP-1;+++[A8MPU2_HUMAN|Unreviewed]SubName: Full=Integrin beta 1 binding protein 1, isoform CRA_g {ECO:0000313|EMBL:EAX00999.1}; SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000352743};+++[B4DQY5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58928, highly similar to Integrin beta-1-binding protein 1 {ECO:0000313|EMBL:BAG61097.1};+++[C9IZZ8_HUMAN|Unreviewed]SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000418947}; Flags: Fragment;+++[C9J0J6_HUMAN|Unreviewed]SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000418526}; Flags: Fragment;+++[C9J5T5_HUMAN|Unreviewed]SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000417940}; Flags: Fragment;+++[C9J6Y2_HUMAN|Unreviewed]SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000417850}; Flags: Fragment;+++[C9JBU8_HUMAN|Unreviewed]SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000420770}; Flags: Fragment;+++[C9JZ07_HUMAN|Unreviewed]SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000419814}; Flags: Fragment;+++[F8WF20_HUMAN|Unreviewed]SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000419452};+++[G3V1A3_HUMAN|Unreviewed]SubName: Full=Integrin beta 1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAX00991.1}; SubName: Full=Integrin beta-1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000433814};+++[Q6IAZ8_HUMAN|Unreviewed]SubName: Full=ITGB1BP1 protein {ECO:0000313|EMBL:CAG33287.1};"]
[9289,"'ADGRG1'",88,83,87,86,null,"H00271///Polymicrogyria",null,null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0045121///membrane raft+++GO:0097451///glial limiting end-foot+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0004930///G protein-coupled receptor activity+++GO:0050840///extracellular matrix binding+++GO:0005518///collagen binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0008201///heparin binding","GO:0007267///cell-cell signaling+++GO:0007165///signal transduction+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:0045785///positive regulation of cell adhesion+++GO:0021819///layer formation in cerebral cortex+++GO:0007420///brain development+++GO:0008285///negative regulation of cell proliferation+++GO:0016477///cell migration+++GO:2001223///negative regulation of neuron migration+++GO:0070528///protein kinase C signaling+++GO:0021801///cerebral cortex radial glia guided migration+++GO:0007266///Rho protein signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0021796///cerebral cortex regionalization+++GO:0001525///angiogenesis+++GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0010573///vascular endothelial growth factor production+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0072520///seminiferous tubule development+++GO:0007186///G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor G1","[AGRG1_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor G1; AltName: Full=G-protein coupled receptor 56; AltName: Full=Protein TM7XN1; Contains: RecName: Full=ADGRG1 N-terminal fragment; Short=ADGRG1 NT; AltName: Full=GPR56 N-terminal fragment; Short=GPR56 NT; Short=GPR56(N); AltName: Full=GPR56 extracellular subunit; AltName: Full=GPR56 subunit alpha; Contains: RecName: Full=ADGRG1 C-terminal fragment; Short=ADGRG1 CT; AltName: Full=GPR56 C-terminal fragment; Short=GPR56 CT; Short=GPR56(C); AltName: Full=GPR56 seven-transmembrane subunit; Short=GPR56 7TM; AltName: Full=GPR56 subunit beta; Flags: Precursor;+++[A0A024R6U7_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 56 isoform 1 {ECO:0000313|EMBL:ALQ33930.1}; SubName: Full=G protein-coupled receptor 56, isoform CRA_b {ECO:0000313|EMBL:EAW82941.1};+++[A0A0S2Z517_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 56 isoform 2 {ECO:0000313|EMBL:ALQ33931.1}; SubName: Full=Testicular tissue protein Li 77 {ECO:0000313|EMBL:AEE60990.1}; Flags: Fragment;+++[A0A1B0GX62_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457307}; Flags: Fragment;+++[B3KQN7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90789 fis, clone THYRO1001523, highly similar to G-protein coupled receptor 56 {ECO:0000313|EMBL:BAG52099.1};+++[B3KQV4_HUMAN|Unreviewed]SubName: Full=cDNA PSEC0255 fis, clone NT2RP3003536, highly similar to G-protein coupled receptor 56 {ECO:0000313|EMBL:BAG52166.1};+++[B4DM06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54072, highly similar to G-protein coupled receptor 56 {ECO:0000313|EMBL:BAG59718.1};+++[H3BM73_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454263}; Flags: Fragment;+++[H3BMC2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454321}; Flags: Fragment;+++[H3BMF8_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454364}; Flags: Fragment;+++[H3BMY9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454607}; Flags: Fragment;+++[H3BNH4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454855}; Flags: Fragment;+++[H3BNN3_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000454933}; Flags: Fragment;+++[H3BP67_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455176}; Flags: Fragment;+++[H3BP94_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455209}; Flags: Fragment;+++[H3BPA6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455226}; Flags: Fragment;+++[H3BPC0_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455245};+++[H3BQ11_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455553}; Flags: Fragment;+++[H3BQ46_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455600}; Flags: Fragment;+++[H3BQJ9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455812}; Flags: Fragment;+++[H3BQW4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000455965}; Flags: Fragment;+++[H3BQZ1_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456002}; Flags: Fragment;+++[H3BRA1_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456147}; Flags: Fragment;+++[H3BRB4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456166}; Flags: Fragment;+++[H3BRH0_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456238}; Flags: Fragment;+++[H3BRI2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456256}; Flags: Fragment;+++[H3BRI7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456263}; Flags: Fragment;+++[H3BRZ4_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456469}; Flags: Fragment;+++[H3BS14_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456494}; Flags: Fragment;+++[H3BS54_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456544}; Flags: Fragment;+++[H3BS94_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456599}; Flags: Fragment;+++[H3BS98_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456603}; Flags: Fragment;+++[H3BSB8_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456632}; Flags: Fragment;+++[H3BSF7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456682}; Flags: Fragment;+++[H3BSJ6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456731}; Flags: Fragment;+++[H3BSN3_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456781}; Flags: Fragment;+++[H3BSN7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456787}; Flags: Fragment;+++[H3BSP5_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456796}; Flags: Fragment;+++[H3BSR1_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000456819}; Flags: Fragment;+++[H3BT88_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457073}; Flags: Fragment;+++[H3BTD2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457122}; Flags: Fragment;+++[H3BTH7_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457178}; Flags: Fragment;+++[H3BTK9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457223}; Flags: Fragment;+++[H3BUF5_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457612};+++[H3BUH2_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457635}; Flags: Fragment;+++[H3BUI6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457657}; Flags: Fragment;+++[H3BUU6_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457806}; Flags: Fragment;+++[H3BV52_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457953}; Flags: Fragment;+++[H3BV72_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457979}; Flags: Fragment;+++[H3BV84_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000457994}; Flags: Fragment;+++[H3BVA0_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000458014}; Flags: Fragment;+++[H3BVD3_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000458063}; Flags: Fragment;+++[H3BVE9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor G1 {ECO:0000313|Ensembl:ENSP00000458087}; Flags: Fragment;"]
[9295,"'SRSF11'",1975,1581,1486,1680.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031124///mRNA 3'-end processing","serine and arginine rich splicing factor 11","[SRS11_HUMAN|Reviewed]RecName: Full=Serine/arginine-rich splicing factor 11; AltName: Full=Arginine-rich 54 kDa nuclear protein; Short=p54; AltName: Full=Splicing factor, arginine/serine-rich 11;+++[B4DWT1_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000474372}; SubName: Full=cDNA FLJ52287, highly similar to Splicing factor arginine/serine-rich 11 {ECO:0000313|EMBL:BAG63143.1};+++[Q05BU6_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH32727.1}; Flags: Fragment;+++[Q5T757_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000359987};+++[Q5T760_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000378568}; Flags: Fragment;+++[Q6PJB9_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH17359.1}; Flags: Fragment;+++[Q6PJY9_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH09840.1}; Flags: Fragment;+++[Q6PKC9_HUMAN|Unreviewed]SubName: Full=SFRS11 protein {ECO:0000313|EMBL:AAH02784.1}; Flags: Fragment;+++[S4R3C4_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 11 {ECO:0000313|Ensembl:ENSP00000474149};"]
[9314,"'KLF4'",62,49,20,43.6666666666667,"04550///Signaling pathways regulating pluripotency of stem cells","H01556///Meningioma",null,null,"GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0005667///transcription factor complex+++GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005719///nuclear euchromatin+++GO:0005737///cytoplasm+++GO:0044798///nuclear transcription factor complex","GO:0003690///double-stranded DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:1990841///promoter-specific chromatin binding+++GO:0046872///metal ion binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0001010///RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0008013///beta-catenin binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042826///histone deacetylase binding+++GO:0008270///zinc ion binding","GO:0019827///stem cell population maintenance+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0030154///cell differentiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0030336///negative regulation of cell migration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0048679///regulation of axon regeneration+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0045595///regulation of cell differentiation+++GO:0045415///negative regulation of interleukin-8 biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0007500///mesodermal cell fate determination+++GO:0071409///cellular response to cycloheximide+++GO:0010629///negative regulation of gene expression+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048730///epidermis morphogenesis+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:1904998///negative regulation of leukocyte adhesion to arterial endothelial cell+++GO:0071300///cellular response to retinoic acid+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0032526///response to retinoic acid+++GO:0016525///negative regulation of angiogenesis+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production+++GO:0014740///negative regulation of muscle hyperplasia+++GO:0045444///fat cell differentiation+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0010033///response to organic substance+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0071363///cellular response to growth factor stimulus+++GO:1901653///cellular response to peptide+++GO:0031077///post-embryonic camera-type eye development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0009913///epidermal cell differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0035166///post-embryonic hemopoiesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:1904798///positive regulation of core promoter binding+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071407///cellular response to organic cyclic compound+++GO:0035019///somatic stem cell population maintenance+++GO:0042127///regulation of cell proliferation+++GO:0051973///positive regulation of telomerase activity+++GO:0010628///positive regulation of gene expression+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:0051247///positive regulation of protein metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060070///canonical Wnt signaling pathway","Kruppel like factor 4","[KLF4_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 4; AltName: Full=Epithelial zinc finger protein EZF; AltName: Full=Gut-enriched krueppel-like factor;+++[A0A087X0S4_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 4 {ECO:0000313|Ensembl:ENSP00000483629};+++[B7ZBT2_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 4 {ECO:0000313|Ensembl:ENSP00000404922}; Flags: Fragment;+++[F2VTX5_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 4 short isoform {ECO:0000313|EMBL:ADL14248.1};+++[L0R3V2_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 4 (Gut) {ECO:0000313|EMBL:CCO02799.1};+++[Q5T3J6_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 4 {ECO:0000313|Ensembl:ENSP00000399921}; Flags: Fragment;"]
[9320,"'TRIP12'",2224,1435,1640,1766.33333333333,"04120///Ubiquitin mediated proteolysis","H00773///Autosomal dominant mental retardation",null,null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046966///thyroid hormone receptor binding+++GO:0004842///ubiquitin-protein transferase activity","GO:2000780///negative regulation of double-strand break repair+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0045995///regulation of embryonic development+++GO:1901315///negative regulation of histone H2A K63-linked ubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination+++GO:0006281///DNA repair","thyroid hormone receptor interactor 12","[TRIPC_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIP12; EC=2.3.2.26; AltName: Full=E3 ubiquitin-protein ligase for Arf; Short=ULF; AltName: Full=HECT-type E3 ubiquitin transferase TRIP12; AltName: Full=Thyroid receptor-interacting protein 12; Short=TR-interacting protein 12; Short=TRIP-12;+++[C9JLD7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIP12 {ECO:0000313|Ensembl:ENSP00000389827}; Flags: Fragment;+++[C9JLJ5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIP12 {ECO:0000313|Ensembl:ENSP00000414385}; Flags: Fragment;+++[C9JSX9_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIP12 {ECO:0000313|Ensembl:ENSP00000409460}; Flags: Fragment;+++[F8W9P3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIP12 {ECO:0000313|Ensembl:ENSP00000342442}; Flags: Fragment;+++[G5E9G6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIP12 {ECO:0000313|Ensembl:ENSP00000386388}; SubName: Full=Thyroid hormone receptor interactor 12, isoform CRA_c {ECO:0000313|EMBL:EAW70898.1};+++[H7C1L9_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIP12 {ECO:0000313|Ensembl:ENSP00000400967}; Flags: Fragment;+++[H7C2Y1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIP12 {ECO:0000313|Ensembl:ENSP00000408330}; Flags: Fragment;+++[L0R5E3_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIP12 {ECO:0000313|EMBL:CCO13843.1};+++[Q57Z94_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TRIP12 {ECO:0000313|EMBL:AAX82004.1}; Flags: Fragment;"]
[9341,"'VAMP3'",1706,1791,1702,1733,"04130///SNARE interactions in vesicular transport+++04145///Phagosome",{"$nulls":3},"GO:0005829///cytosol+++GO:0030670///phagocytic vesicle membrane+++GO:0030133///transport vesicle+++GO:0055038///recycling endosome membrane+++GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0031201///SNARE complex+++GO:0005622///intracellular+++GO:0045202///synapse+++GO:0031410///cytoplasmic vesicle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0055037///recycling endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0043005///neuron projection+++GO:0009986///cell surface+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0030136///clathrin-coated vesicle+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0043229///intracellular organelle+++GO:0016020///membrane+++GO:0045335///phagocytic vesicle+++GO:0032588///trans-Golgi network membrane","GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding","GO:0035493///SNARE complex assembly+++GO:0001921///positive regulation of receptor recycling+++GO:0061024///membrane organization+++GO:1903531///negative regulation of secretion by cell+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0065003///protein-containing complex assembly+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0016192///vesicle-mediated transport+++GO:1903593///regulation of histamine secretion by mast cell+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0006904///vesicle docking involved in exocytosis+++GO:0071346///cellular response to interferon-gamma+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0017156///calcium ion regulated exocytosis+++GO:0070254///mucus secretion+++GO:0006887///exocytosis+++GO:0015031///protein transport","vesicle associated membrane protein 3","[VAMP3_HUMAN|Reviewed]RecName: Full=Vesicle-associated membrane protein 3; Short=VAMP-3; AltName: Full=Cellubrevin; Short=CEB; AltName: Full=Synaptobrevin-3;+++[K7EKX0_HUMAN|Unreviewed]SubName: Full=Vesicle-associated membrane protein 3 {ECO:0000313|Ensembl:ENSP00000465820};+++[Q6FGG2_HUMAN|Unreviewed]SubName: Full=VAMP3 protein {ECO:0000313|EMBL:CAG46942.1}; SubName: Full=Vesicle-associated membrane protein 3 (Cellubrevin) {ECO:0000313|EMBL:EAW71582.1}; SubName: Full=cDNA, FLJ92013, Homo sapiens vesicle-associated membrane protein 3 (cellubrevin)(VAMP3), mRNA {ECO:0000313|EMBL:BAG38147.1};"]
[9351,"'SLC9A3R2'",1155,1225,1072,1150.66666666667,"04960///Aldosterone-regulated sodium reabsorption",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005925///focal adhesion+++GO:0016324///apical plasma membrane+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0008013///beta-catenin binding+++GO:0019902///phosphatase binding+++GO:0045296///cadherin binding+++GO:0008022///protein C-terminus binding","GO:0065003///protein-containing complex assembly","SLC9A3 regulator 2","[NHRF2_HUMAN|Reviewed]RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF2; Short=NHERF-2; AltName: Full=NHE3 kinase A regulatory protein E3KARP; AltName: Full=SRY-interacting protein 1; Short=SIP-1; AltName: Full=Sodium-hydrogen exchanger regulatory factor 2; AltName: Full=Solute carrier family 9 isoform A3 regulatory factor 2; AltName: Full=Tyrosine kinase activator protein 1; Short=TKA-1;+++[H3BMF5_HUMAN|Unreviewed]SubName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF2 {ECO:0000313|Ensembl:ENSP00000454361}; Flags: Fragment;+++[H3BN50_HUMAN|Unreviewed]SubName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF2 {ECO:0000313|Ensembl:ENSP00000454690}; Flags: Fragment;+++[H3BQS0_HUMAN|Unreviewed]SubName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF2 {ECO:0000313|Ensembl:ENSP00000455909};+++[H3BUQ9_HUMAN|Unreviewed]SubName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF2 {ECO:0000313|Ensembl:ENSP00000457755}; Flags: Fragment;+++[Q6NTG0_HUMAN|Unreviewed]SubName: Full=SLC9A3R2 protein {ECO:0000313|EMBL:AAH69014.1}; Flags: Fragment;"]
[93649,"'MYOCD'",25,10,24,19.6666666666667,{"$nulls":4},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0061629///RNA polymerase II sequence-specific DNA-binding transcription factor binding+++GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0042826///histone deacetylase binding+++GO:0070412///R-SMAD binding+++GO:0035035///histone acetyltransferase binding+++GO:0008134///transcription factor binding+++GO:0000987///proximal promoter sequence-specific DNA binding","GO:0060065///uterus development+++GO:0001666///response to hypoxia+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045661///regulation of myoblast differentiation+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0035065///regulation of histone acetylation+++GO:0001560///regulation of cell growth by extracellular stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0003257///positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0007507///heart development+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0048565///digestive tract development+++GO:0001570///vasculogenesis+++GO:1901228///positive regulation of transcription from RNA polymerase II promoter involved in heart development+++GO:1904753///negative regulation of vascular associated smooth muscle cell migration+++GO:0043954///cellular component maintenance+++GO:0042692///muscle cell differentiation+++GO:0051150///regulation of smooth muscle cell differentiation+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0043388///positive regulation of DNA binding+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0097070///ductus arteriosus closure+++GO:2000724///positive regulation of cardiac vascular smooth muscle cell differentiation+++GO:0055012///ventricular cardiac muscle cell differentiation+++GO:2000721///positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation+++GO:1900222///negative regulation of amyloid-beta clearance+++GO:0035051///cardiocyte differentiation+++GO:0055007///cardiac muscle cell differentiation+++GO:1900239///regulation of phenotypic switching+++GO:0035886///vascular smooth muscle cell differentiation+++GO:0060157///urinary bladder development+++GO:0008285///negative regulation of cell proliferation+++GO:0008284///positive regulation of cell proliferation+++GO:0051145///smooth muscle cell differentiation+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:2001015///negative regulation of skeletal muscle cell differentiation+++GO:0048286///lung alveolus development+++GO:0003231///cardiac ventricle development+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0010832///negative regulation of myotube differentiation","myocardin","[MYCD_HUMAN|Reviewed]RecName: Full=Myocardin;+++[J3KSX3_HUMAN|Unreviewed]SubName: Full=Myocardin {ECO:0000313|Ensembl:ENSP00000462694};+++[Q6N065_HUMAN|Unreviewed]SubName: Full=Myocardin {ECO:0000313|Ensembl:ENSP00000400148}; Flags: Fragment;"]
[9374,"'PPT2'",239,251,258,249.333333333333,"01100///Metabolic pathways+++04142///Lysosome+++00062///Fatty acid elongation+++01212///Fatty acid metabolism","H00149///Neuronal ceroid lipofuscinosis (NCL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,"R01274///palmitoyl-CoA hydrolase   Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid","GO:0043202///lysosomal lumen+++GO:0005764///lysosome+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0098599///palmitoyl hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0016787///hydrolase activity","GO:0098734///macromolecule depalmitoylation+++GO:0046949///fatty-acyl-CoA biosynthetic process","palmitoyl-protein thioesterase 2","[PPT2_HUMAN|Reviewed]RecName: Full=Lysosomal thioesterase PPT2; Short=PPT-2; EC=3.1.2.-; AltName: Full=S-thioesterase G14; Flags: Precursor;+++[A0A024RCQ8_HUMAN|Unreviewed]SubName: Full=HCG1999928, isoform CRA_a {ECO:0000313|EMBL:EAX03592.1}; SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000382748}; SubName: Full=PPT2 {ECO:0000313|EMBL:AQY77052.1};+++[A0A0G2JH76_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000382570};+++[A0A0G2JHB6_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000387444}; Flags: Fragment;+++[A0A0G2JHI0_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000389505}; Flags: Fragment;+++[A0A0G2JI52_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000395212}; Flags: Fragment;+++[A0A0G2JID8_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000397767}; Flags: Fragment;+++[A0A0G2JIU6_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000402159}; Flags: Fragment;+++[A0A0G2JK02_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000412655}; Flags: Fragment;+++[A0A0G2JK07_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000412844}; Flags: Fragment;+++[A0A0G2JKR3_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000435258}; Flags: Fragment;+++[A0A0G2JLK3_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000475276}; Flags: Fragment;+++[A0A0G2JLK6_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000475728};+++[A0A0G2JLK8_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000475954};+++[A0A0G2JLK9_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000431652}; Flags: Fragment;+++[A0A140T8X7_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000372637};+++[A0A140T9Y1_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000416062}; Flags: Fragment;+++[A0A140TA16_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000435187}; Flags: Fragment;+++[A0A1U9X8D2_HUMAN|Unreviewed]SubName: Full=PPT2 {ECO:0000313|EMBL:AQY77051.1};+++[A2ABN6_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000395456}; SubName: Full=PPT2-EGFL8 readthrough (NMD candidate) {ECO:0000313|Ensembl:ENSP00000461909};+++[A2ABN7_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000409877}; Flags: Fragment;+++[G8JLL2_HUMAN|Unreviewed]SubName: Full=Lysosomal thioesterase PPT2 {ECO:0000313|Ensembl:ENSP00000398847}; Flags: Fragment;"]
[93974,"'ATP5IF1'",2034,2254,1709,1999,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0009986///cell surface","GO:0042803///protein homodimerization activity+++GO:0043532///angiostatin binding+++GO:0042030///ATPase inhibitor activity+++GO:0051117///ATPase binding+++GO:0019899///enzyme binding+++GO:0005516///calmodulin binding+++GO:0004857///enzyme inhibitor activity+++GO:0140260///mitochondrial proton-transporting ATP synthase complex binding","GO:0006091///generation of precursor metabolites and energy+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process+++GO:0051882///mitochondrial depolarization+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0006783///heme biosynthetic process+++GO:0030218///erythrocyte differentiation+++GO:0001525///angiogenesis+++GO:0032780///negative regulation of ATPase activity+++GO:0051346///negative regulation of hydrolase activity+++GO:0051289///protein homotetramerization+++GO:0072593///reactive oxygen species metabolic process+++GO:0051260///protein homooligomerization+++GO:1903578///regulation of ATP metabolic process+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:1904925///positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization+++GO:0001937///negative regulation of endothelial cell proliferation","ATP synthase inhibitory factor subunit 1","[ATIF1_HUMAN|Reviewed]RecName: Full=ATPase inhibitor, mitochondrial {ECO:0000305}; AltName: Full=ATP synthase F1 subunit epsilon {ECO:0000305}; AltName: Full=Inhibitor of F(1)F(o)-ATPase; Short=IF(1); Short=IF1; Flags: Precursor;+++[A0A0B4J230_HUMAN|Unreviewed]SubName: Full=ATPase inhibitor, mitochondrial {ECO:0000313|Ensembl:ENSP00000435341};"]
[93979,"'CPA5'",1,1,3,1.66666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008237///metallopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008233///peptidase activity","GO:0006508///proteolysis","carboxypeptidase A5","[CBPA5_HUMAN|Reviewed]RecName: Full=Carboxypeptidase A5; EC=3.4.17.-; Flags: Precursor;+++[A0A1D5RMQ7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000419013}; Flags: Fragment;+++[A4D1M2_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|EMBL:EAL24090.1}; SubName: Full=Carboxypeptidase A5, isoform CRA_a {ECO:0000313|EMBL:EAW83754.1}; SubName: Full=Testicular tissue protein Li 32 {ECO:0000313|EMBL:AEE60945.1};+++[B2RCS8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ96260, highly similar to Homo sapiens carboxypeptidase A5 (CPA5), mRNA {ECO:0000313|EMBL:BAG37675.1};+++[C9JRV5_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000420060}; Flags: Fragment;+++[C9JZE9_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000419778}; Flags: Fragment;+++[H7C4Q6_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000417886}; Flags: Fragment;"]
[94107,"'TMEM203'",338,333,370,347,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0007283///spermatogenesis+++GO:0006874///cellular calcium ion homeostasis","transmembrane protein 203","[TM203_HUMAN|Reviewed]RecName: Full=Transmembrane protein 203;+++[Q7Z4H1_HUMAN|Unreviewed]SubName: Full=HBeAg-binding protein 1 {ECO:0000313|EMBL:AAQ09606.1};"]
[9412,"'MED21'",205,155,154,171.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0016592///mediator complex+++GO:0000151///ubiquitin ligase complex","GO:0061630///ubiquitin protein ligase activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity","GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0001824///blastocyst development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032774///RNA biosynthetic process","mediator complex subunit 21","[MED21_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 21; AltName: Full=Mediator complex subunit 21; AltName: Full=RNA polymerase II holoenzyme component SRB7; Short=RNAPII complex component SRB7; Short=hSrb7;+++[A0A024RAW0_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit 21 isoform 1 {ECO:0000313|EMBL:ALQ33932.1}; SubName: Full=SRB7 suppressor of RNA polymerase B homolog (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW96547.1};+++[A0A0S2Z545_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit 21 isoform 2 {ECO:0000313|EMBL:ALQ33933.1};+++[F5GZQ1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 21 {ECO:0000313|Ensembl:ENSP00000444297};+++[F5H872_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 21 {ECO:0000313|Ensembl:ENSP00000442126};"]
[94234,"'FOXQ1'",36,49,36,40.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0009653///anatomical structure morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031069///hair follicle morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II","forkhead box Q1","[FOXQ1_HUMAN|Reviewed]RecName: Full=Forkhead box protein Q1; AltName: Full=HNF-3/forkhead-like protein 1; Short=HFH-1; AltName: Full=Hepatocyte nuclear factor 3 forkhead homolog 1;"]
[9444,"'QKI'",1530,1205,1287,1340.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0017124///SH3 domain binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0006397///mRNA processing+++GO:0030154///cell differentiation+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0006417///regulation of translation+++GO:0051028///mRNA transport","QKI, KH domain containing RNA binding","[QKI_HUMAN|Reviewed]RecName: Full=Protein quaking; Short=Hqk; Short=HqkI;+++[F5GXS8_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000440991}; Flags: Fragment;+++[F5GYM3_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000440599}; Flags: Fragment;+++[F5GYT7_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000441252};+++[F5H5U6_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000443106}; Flags: Fragment;+++[F5H8C8_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000443690}; Flags: Fragment;+++[H0YFB7_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000437867}; Flags: Fragment;+++[H0YG47_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000441773}; Flags: Fragment;+++[H0YGD6_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000442848}; Flags: Fragment;+++[Q8WY44_HUMAN|Unreviewed]SubName: Full=Quaking protein 3 {ECO:0000313|EMBL:AAL36980.1}; Flags: Fragment;"]
[9465,"'AKAP7'",63,57,69,63,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0098686///hippocampal mossy fiber to CA3 synapse","GO:0000166///nucleotide binding+++GO:0019901///protein kinase binding+++GO:0051018///protein kinase A binding+++GO:0005515///protein binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0016301///kinase activity","GO:0010738///regulation of protein kinase A signaling+++GO:1902261///positive regulation of delayed rectifier potassium channel activity+++GO:0071320///cellular response to cAMP+++GO:0008104///protein localization+++GO:0008150///biological_process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060306///regulation of membrane repolarization+++GO:0001508///action potential+++GO:0006811///ion transport+++GO:0035556///intracellular signal transduction+++GO:0016310///phosphorylation+++GO:1901381///positive regulation of potassium ion transmembrane transport","A-kinase anchoring protein 7","[AKA7A_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 7 isoforms alpha and beta; Short=AKAP-7 isoforms alpha and beta; AltName: Full=A-kinase anchor protein 18 kDa; Short=AKAP 18; AltName: Full=Protein kinase A-anchoring protein 7 isoforms alpha/beta; Short=PRKA7 isoforms alpha/beta;+++[AKA7G_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 7 isoform gamma; Short=AKAP-7 isoform gamma; AltName: Full=A-kinase anchor protein 18 kDa; Short=AKAP 18; AltName: Full=Protein kinase A-anchoring protein 7 isoform gamma; Short=PRKA7 isoform gamma;+++[F5GXD1_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000441048};+++[F5H4P9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000446022};+++[H0YH01_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000445486}; Flags: Fragment;+++[J3KN37_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000263050};+++[Q2TAJ5_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein 7 {ECO:0000313|EMBL:AAI10898.1}; SubName: Full=A kinase (PRKA) anchor protein 7, isoform CRA_c {ECO:0000313|EMBL:EAW48059.1}; SubName: Full=A-kinase anchor protein 7 isoform alpha {ECO:0000313|EMBL:BAG70087.1}; SubName: Full=cDNA, FLJ92081, Homo sapiens A kinase (PRKA) anchor protein 7 (AKAP7), transcriptvariant alpha, mRNA {ECO:0000313|EMBL:BAG34762.1};+++[Q6P4D3_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein 7 {ECO:0000313|EMBL:AAH63499.1};"]
[9480,"'ONECUT2'",19,18,18,18.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0015629///actin cytoskeleton","GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0030335///positive regulation of cell migration+++GO:0009653///anatomical structure morphogenesis+++GO:0031018///endocrine pancreas development+++GO:0009887///animal organ morphogenesis+++GO:0045165///cell fate commitment+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0060271///cilium assembly+++GO:0048935///peripheral nervous system neuron development+++GO:0001889///liver development+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031016///pancreas development+++GO:0001952///regulation of cell-matrix adhesion+++GO:0002064///epithelial cell development","one cut homeobox 2","[ONEC2_HUMAN|Reviewed]RecName: Full=One cut domain family member 2; AltName: Full=Hepatocyte nuclear factor 6-beta; Short=HNF-6-beta; AltName: Full=One cut homeobox 2; AltName: Full=Transcription factor ONECUT-2; Short=OC-2;"]
[9501,"'RPH3AL'",18,17,24,19.6666666666667,{"$nulls":4},"GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005623///cell","GO:0030274///LIM domain binding+++GO:0017137///Rab GTPase binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding","GO:0017157///regulation of exocytosis+++GO:0042593///glucose homeostasis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0042493///response to drug+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis","rabphilin 3A like (without C2 domains)","[RPH3L_HUMAN|Reviewed]RecName: Full=Rab effector Noc2; AltName: Full=No C2 domains protein; AltName: Full=Rabphilin-3A-like protein;+++[A0A0J9YWA6_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000487877}; Flags: Fragment;+++[A0A0J9YX72_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000488277}; Flags: Fragment;+++[A8K7D5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77349, highly similar to Homo sapiens rabphilin 3A-like (without C2 domains), mRNA {ECO:0000313|EMBL:BAF84639.1};+++[I3L181_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000458643}; Flags: Fragment;+++[I3L1Q0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459001}; Flags: Fragment;+++[I3L2G8_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459666}; Flags: Fragment;+++[I3L2I9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459716}; Flags: Fragment;+++[I3L2N0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459795}; Flags: Fragment;+++[I3L2W0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459975}; Flags: Fragment;+++[I3L2X0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459992}; Flags: Fragment;+++[I3L308_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460080}; Flags: Fragment;+++[I3L349_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460171}; Flags: Fragment;+++[I3L3M9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460580}; Flags: Fragment;+++[I3NI49_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000461885}; Flags: Fragment;"]
[9520,"'NPEPPS'",1629.08,1398.86,1426.21,1484.71666666667,"03013///RNA transport",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0042277///peptide binding+++GO:0016787///hydrolase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0004177///aminopeptidase activity+++GO:0046872///metal ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0008233///peptidase activity","GO:0043171///peptide catabolic process+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0071456///cellular response to hypoxia+++GO:0000209///protein polyubiquitination+++GO:0006508///proteolysis","aminopeptidase puromycin sensitive","[PSA_HUMAN|Reviewed]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;+++[B7Z899_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040};+++[E9PI82_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000436733};+++[E9PJ74_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000435639}; Flags: Fragment;+++[E9PJF9_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000433735};+++[E9PJY4_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000433649}; Flags: Fragment;+++[E9PLK3_HUMAN|Unreviewed]RecName: Full=Aminopeptidase {ECO:0000256|RuleBase:RU364040}; EC=3.4.11.- {ECO:0000256|RuleBase:RU364040};+++[E9PP11_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000437019}; Flags: Fragment;+++[E9PPD4_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000434585};+++[E9PPZ2_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000434554};+++[E9PRQ5_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000435966}; Flags: Fragment;+++[H0YCQ5_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000432127}; Flags: Fragment;+++[H0YDG0_HUMAN|Unreviewed]SubName: Full=Puromycin-sensitive aminopeptidase {ECO:0000313|Ensembl:ENSP00000433549}; Flags: Fragment;"]
[9538,"'EI24'",1419,1422,1446,1429,"04115///p53 signaling pathway",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane",null,"GO:0016236///macroautophagy+++GO:0006914///autophagy+++GO:0030308///negative regulation of cell growth+++GO:0006915///apoptotic process","EI24, autophagy associated transmembrane protein","[EI24_HUMAN|Reviewed]RecName: Full=Etoposide-induced protein 2.4 homolog; AltName: Full=p53-induced gene 8 protein;+++[A0A024R3I8_HUMAN|Unreviewed]SubName: Full=Etoposide induced 2.4 mRNA, isoform CRA_a {ECO:0000313|EMBL:EAW67642.1};+++[A0A087WV44_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000479171};+++[B7ZB74_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000477849}; SubName: Full=cDNA, FLJ79438, highly similar to Etoposide-induced protein 2.4 {ECO:0000313|EMBL:BAH14910.1};+++[E9PK61_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000431633};+++[E9PL33_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000433376}; Flags: Fragment;+++[E9PLB8_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000435225}; Flags: Fragment;+++[E9PM05_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000435034}; Flags: Fragment;+++[E9PQN7_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000436130}; Flags: Fragment;+++[E9PS58_HUMAN|Unreviewed]SubName: Full=Etoposide-induced protein 2.4 homolog {ECO:0000313|Ensembl:ENSP00000435923}; Flags: Fragment;"]
[9554,"'SEC22B'",1564.57,1300.28,1316.38,1393.74333333333,"04145///Phagosome+++05134///Legionellosis+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0030670///phagocytic vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0042470///melanosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0008021///synaptic vesicle+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0030133///transport vesicle+++GO:0031201///SNARE complex","GO:0005515///protein binding+++GO:0019905///syntaxin binding+++GO:0005484///SNAP receptor activity","GO:0045732///positive regulation of protein catabolic process+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:1902902///negative regulation of autophagosome assembly+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER","SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)","[SC22B_HUMAN|Reviewed]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[A0A087X1A9_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22b {ECO:0000313|Ensembl:ENSP00000484017}; Flags: Fragment;+++[I1VE16_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41826.1}; Flags: Fragment;+++[I1VE17_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41827.1}; Flags: Fragment;+++[I1VE18_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41828.1}; Flags: Fragment;+++[I1VE19_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41829.1}; Flags: Fragment;+++[I1VE20_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41830.1}; Flags: Fragment;"]
[9578,"'CDC42BPB'",4569,4450,4267,4428.66666666667,{"$nulls":4},"GO:0042995///cell projection+++GO:0042641///actomyosin+++GO:0005737///cytoplasm+++GO:0031252///cell leading edge+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0005911///cell-cell junction+++GO:0030027///lamellipodium+++GO:0005856///cytoskeleton","GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0017048///Rho GTPase binding+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity","GO:0031532///actin cytoskeleton reorganization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0035556///intracellular signal transduction+++GO:0016477///cell migration+++GO:0031032///actomyosin structure organization+++GO:0006468///protein phosphorylation+++GO:0007165///signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0016310///phosphorylation+++GO:0007010///cytoskeleton organization","CDC42 binding protein kinase beta","[MRCKB_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase MRCK beta; EC=2.7.11.1; AltName: Full=CDC42-binding protein kinase beta; Short=CDC42BP-beta; AltName: Full=DMPK-like beta; AltName: Full=Myotonic dystrophy kinase-related CDC42-binding kinase beta; Short=MRCK beta; Short=Myotonic dystrophy protein kinase-like beta;+++[A0A024R6N2_HUMAN|Unreviewed]SubName: Full=CDC42 binding protein kinase beta (DMPK-like), isoform CRA_a {ECO:0000313|EMBL:EAW81801.1};+++[A0A0U1RRC3_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase MRCK beta {ECO:0000313|Ensembl:ENSP00000489452}; Flags: Fragment;+++[H0YLY0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase MRCK beta {ECO:0000313|Ensembl:ENSP00000453384}; Flags: Fragment;+++[Q86XZ8_HUMAN|Unreviewed]SubName: Full=CDC42BPB protein {ECO:0000313|EMBL:AAH48261.1}; Flags: Fragment;"]
[9590,"'AKAP12'",633,343,432,469.333333333333,{"$nulls":4},"GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005938///cell cortex","GO:0008179///adenylate cyclase binding+++GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0090036///regulation of protein kinase C signaling+++GO:0010738///regulation of protein kinase A signaling+++GO:0006605///protein targeting+++GO:0050804///modulation of chemical synaptic transmission+++GO:0010739///positive regulation of protein kinase A signaling+++GO:0007165///signal transduction+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway","A-kinase anchoring protein 12","[AKA12_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 12; Short=AKAP-12; AltName: Full=A-kinase anchor protein 250 kDa; Short=AKAP 250; AltName: Full=Gravin; AltName: Full=Myasthenia gravis autoantigen;+++[Q6NSG9_HUMAN|Unreviewed]SubName: Full=AKAP12 protein {ECO:0000313|EMBL:AAH70151.1}; Flags: Fragment;+++[Q86TJ9_HUMAN|Unreviewed]SubName: Full=AKAP12 protein {ECO:0000313|EMBL:AAH47728.1}; Flags: Fragment;"]
[9625,"'AATK'",139,153,192,161.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding","GO:0016310///phosphorylation+++GO:0008150///biological_process+++GO:0006468///protein phosphorylation","apoptosis associated tyrosine kinase","[LMTK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase LMTK1; EC=2.7.11.1; AltName: Full=Apoptosis-associated tyrosine kinase; Short=AATYK; AltName: Full=Brain apoptosis-associated tyrosine kinase; AltName: Full=CDK5-binding protein; AltName: Full=Lemur tyrosine kinase 1; AltName: Full=p35-binding protein; Short=p35BP;+++[H7C175_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase LMTK1 {ECO:0000313|Ensembl:ENSP00000398796};+++[I3L360_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase LMTK1 {ECO:0000313|Ensembl:ENSP00000460202}; Flags: Fragment;+++[I3L461_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase LMTK1 {ECO:0000313|Ensembl:ENSP00000460986}; Flags: Fragment;"]
[9639,"'ARHGEF10'",1389,1197,1186,1257.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005813///centrosome","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0019894///kinesin binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0090307///mitotic spindle assembly+++GO:0035023///regulation of Rho protein signal transduction+++GO:0051298///centrosome duplication+++GO:0022011///myelination in peripheral nervous system+++GO:0090630///activation of GTPase activity+++GO:0051496///positive regulation of stress fiber assembly","Rho guanine nucleotide exchange factor 10","[ARHGA_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 10;+++[A0A2X0U4L4_HUMAN|Unreviewed]SubName: Full=ARHGEF10 {ECO:0000313|EMBL:SPT35720.1}; Flags: Fragment;+++[E9PB39_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 10 {ECO:0000313|Ensembl:ENSP00000381568};+++[H0YAN8_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 10 {ECO:0000313|Ensembl:ENSP00000427768}; Flags: Fragment;"]
[966,"'CD59'",6356,6385,5701,6147.33333333333,"04640///Hematopoietic cell lineage+++04610///Complement and coagulation cascades","H00106///Complement regulatory protein defects",null,null,"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0070062///extracellular exosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0035579///specific granule membrane+++GO:0009986///cell surface+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0031982///vesicle+++GO:0031362///anchored component of external side of plasma membrane+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0030133///transport vesicle+++GO:0070821///tertiary granule membrane","GO:0001848///complement binding+++GO:0005515///protein binding","GO:0001971///negative regulation of activation of membrane attack complex+++GO:0048208///COPII vesicle coating+++GO:0030449///regulation of complement activation+++GO:0007596///blood coagulation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043312///neutrophil degranulation+++GO:0007166///cell surface receptor signaling pathway","CD59 molecule (CD59 blood group)","[CD59_HUMAN|Reviewed]RecName: Full=CD59 glycoprotein; AltName: Full=1F5 antigen; AltName: Full=20 kDa homologous restriction factor; Short=HRF-20; Short=HRF20; AltName: Full=MAC-inhibitory protein; Short=MAC-IP; AltName: Full=MEM43 antigen; AltName: Full=Membrane attack complex inhibition factor; Short=MACIF; AltName: Full=Membrane inhibitor of reactive lysis; Short=MIRL; AltName: Full=Protectin; AltName: CD_antigen=CD59; Flags: Precursor;+++[A0A2U3TZL5_HUMAN|Unreviewed]SubName: Full=CD59 glycoprotein {ECO:0000313|Ensembl:ENSP00000434617}; Flags: Fragment;+++[E9PI80_HUMAN|Unreviewed]SubName: Full=CD59 glycoprotein {ECO:0000313|Ensembl:ENSP00000436737};+++[Q6FHM9_HUMAN|Unreviewed]SubName: Full=CD59 antigen, complement regulatory protein, isoform CRA_b {ECO:0000313|EMBL:EAW68193.1}; SubName: Full=CD59 protein {ECO:0000313|EMBL:CAG46523.1}; SubName: Full=cDNA, FLJ92039, Homo sapiens CD59 antigen p18-20 (antigen identified by monoclonalantibodies 16.3A5, EJ16, EJ30, EL32 and G344) (CD59), mRNA {ECO:0000313|EMBL:BAG34721.1};"]
[9671,"'WSCD2'",1,3,0,1.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"WSC domain containing 2","[WSCD2_HUMAN|Reviewed]RecName: Full=WSC domain-containing protein 2;+++[F8W030_HUMAN|Unreviewed]SubName: Full=WSC domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000446744}; Flags: Fragment;"]
[9695,"'EDEM1'",298,208,256,254,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016235///aggresome+++GO:0005783///endoplasmic reticulum","GO:0005509///calcium ion binding+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0005515///protein binding+++GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity+++GO:0016787///hydrolase activity+++GO:0051787///misfolded protein binding+++GO:0003824///catalytic activity","GO:1904382///mannose trimming involved in glycoprotein ERAD pathway+++GO:0006986///response to unfolded protein+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:0036510///trimming of terminal mannose on C branch+++GO:0008152///metabolic process+++GO:0097466///ubiquitin-dependent glycoprotein ERAD pathway+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0036498///IRE1-mediated unfolded protein response","ER degradation enhancing alpha-mannosidase like protein 1","[EDEM1_HUMAN|Reviewed]RecName: Full=ER degradation-enhancing alpha-mannosidase-like protein 1;+++[A0A024R2D5_HUMAN|Unreviewed]RecName: Full=alpha-1,2-Mannosidase {ECO:0000256|RuleBase:RU361193}; EC=3.2.1.- {ECO:0000256|RuleBase:RU361193};+++[F8WE67_HUMAN|Unreviewed]SubName: Full=ER degradation-enhancing alpha-mannosidase-like protein 1 {ECO:0000313|Ensembl:ENSP00000394615};+++[F8WER9_HUMAN|Unreviewed]RecName: Full=alpha-1,2-Mannosidase {ECO:0000256|RuleBase:RU361193}; EC=3.2.1.- {ECO:0000256|RuleBase:RU361193};"]
[9702,"'CEP57'",227,206,179,204,"01100///Metabolic pathways+++00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system","H01288///Mosaic variegated aneuploidy (MVA) syndrome",null,null,"GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center","GO:0042803///protein homodimerization activity+++GO:0043015///gamma-tubulin binding+++GO:0017134///fibroblast growth factor binding+++GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0097711///ciliary basal body-plasma membrane docking+++GO:0051260///protein homooligomerization+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000060///protein import into nucleus, translocation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0034453///microtubule anchoring+++GO:0007286///spermatid development","centrosomal protein 57","[CEP57_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 57 kDa; Short=Cep57; AltName: Full=FGF2-interacting protein; AltName: Full=Testis-specific protein 57; AltName: Full=Translokin;+++[A0A024R3A1_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 57kDa, isoform CRA_a {ECO:0000313|EMBL:EAW66966.1};+++[A0A024R3B1_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 57kDa, isoform CRA_b {ECO:0000313|EMBL:EAW66970.1};+++[A0A024R3D1_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 57kDa, isoform CRA_c {ECO:0000313|EMBL:EAW66969.1};+++[F5GXS6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000440996};+++[F5GYW0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000441392};+++[F5GZ93_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000443866};+++[F5H0C6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000438065}; Flags: Fragment;+++[F5H1B0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000445821}; Flags: Fragment;+++[F5H6R3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000437422};+++[F5H7J4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000442481};+++[H0YFT8_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000440256}; Flags: Fragment;+++[H0YGT4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 57 kDa {ECO:0000313|Ensembl:ENSP00000444749}; Flags: Fragment;"]
[9711,"'RUBCN'",675.52,606.06,622.28,634.62,"04140///Autophagy - animal","H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0005770///late endosome+++GO:0005769///early endosome","GO:0005515///protein binding","GO:0071985///multivesicular body sorting pathway+++GO:0006897///endocytosis+++GO:1901097///negative regulation of autophagosome maturation+++GO:0002376///immune system process+++GO:0006914///autophagy+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0045806///negative regulation of endocytosis+++GO:0010507///negative regulation of autophagy+++GO:0006909///phagocytosis","RUN and cysteine rich domain containing beclin 1 interacting protein","[RUBIC_HUMAN|Reviewed]RecName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000312|HGNC:HGNC:28991}; Short=Rubicon; AltName: Full=Beclin-1 associated RUN domain containing protein; Short=Baron;+++[A0A096LNI3_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000485041}; Flags: Fragment;+++[E9PEM3_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000390962};+++[H0Y6E6_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000405115}; Flags: Fragment;+++[H7C357_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000409618}; Flags: Fragment;+++[H7C3H3_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000411894}; Flags: Fragment;+++[Q8N4U6_HUMAN|Unreviewed]SubName: Full=KIAA0226 protein {ECO:0000313|EMBL:AAH33615.1};"]
[9728,"'SECISBP2L'",621,290,417,442.666666666667,{"$nulls":4},"GO:1990904///ribonucleoprotein complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0003730///mRNA 3'-UTR binding","GO:0001514///selenocysteine incorporation","SECIS binding protein 2 like","[SBP2L_HUMAN|Reviewed]RecName: Full=Selenocysteine insertion sequence-binding protein 2-like; Short=SECIS-binding protein 2-like;+++[A0A024R5R0_HUMAN|Unreviewed]SubName: Full=KIAA0256 gene product, isoform CRA_a {ECO:0000313|EMBL:EAW77362.1};+++[H0YKY4_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000452987}; Flags: Fragment;+++[H0YNT4_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000454144}; Flags: Fragment;+++[J3KPI1_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000370314}; Flags: Fragment;"]
[9729,"'KIAA0408'",0,0,3.29,1.09666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"KIAA0408","[K0408_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0408;+++[E9PQS0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000434384}; Flags: Fragment;+++[H0YEM8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000436178}; Flags: Fragment;"]
[973,"'CD79A'",80,100,89,89.6666666666667,"04662///B cell receptor signaling pathway+++05340///Primary immunodeficiency","H00085///Agammaglobulinemias",null,null,"GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0019815///B cell receptor complex+++GO:0009897///external side of plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0051289///protein homotetramerization+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0050853///B cell receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0007166///cell surface receptor signaling pathway+++GO:0042100///B cell proliferation+++GO:0042113///B cell activation","CD79a molecule","[CD79A_HUMAN|Reviewed]RecName: Full=B-cell antigen receptor complex-associated protein alpha chain; AltName: Full=Ig-alpha; AltName: Full=MB-1 membrane glycoprotein; AltName: Full=Membrane-bound immunoglobulin-associated protein; AltName: Full=Surface IgM-associated protein; AltName: CD_antigen=CD79a; Flags: Precursor;+++[M0QX61_HUMAN|Unreviewed]SubName: Full=B-cell antigen receptor complex-associated protein alpha chain {ECO:0000313|Ensembl:ENSP00000468922}; Flags: Fragment;"]
[9730,"'DCAF1'",416,318,405,379.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome+++GO:0001650///fibrillar center+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex","GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990244///histone kinase activity (H2A-T120 specific)+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0030331///estrogen receptor binding","GO:0030183///B cell differentiation+++GO:0016032///viral process+++GO:0033151///V(D)J recombination+++GO:0016310///phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1990245///histone H2A-T120 phosphorylation+++GO:0006325///chromatin organization+++GO:0016567///protein ubiquitination+++GO:0035212///cell competition in a multicellular organism","DDB1 and CUL4 associated factor 1","[DCAF1_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911}; AltName: Full=HIV-1 Vpr-binding protein; Short=VprBP; AltName: Full=Serine/threonine-protein kinase VPRBP; EC=2.7.11.1; AltName: Full=Vpr-interacting protein;"]
[9731,"'CEP104'",637,589.19,586.72,604.303333333333,null,"H00530///Joubert syndrome",null,null,"GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0005814///centriole+++GO:0000922///spindle pole","GO:0016594///glycine binding+++GO:0016595///glutamate binding+++GO:0016596///thienylcyclohexylpiperidine binding+++GO:0005515///protein binding",null,"centrosomal protein 104","[CE104_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 104 kDa; Short=Cep104;+++[H7C0J5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000395283}; Flags: Fragment;+++[J3QLL3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000463605}; Flags: Fragment;+++[Q5SR26_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000411927}; Flags: Fragment;+++[Q5SR27_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000394989}; Flags: Fragment;"]
[9732,"'DOCK4'",64,49,54,55.6666666666667,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0005096///GTPase activator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0048365///Rac GTPase binding+++GO:0017124///SH3 domain binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030165///PDZ domain binding+++GO:0005515///protein binding","GO:1904694///negative regulation of vascular smooth muscle contraction+++GO:0007264///small GTPase mediated signal transduction+++GO:0060326///cell chemotaxis+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0043547///positive regulation of GTPase activity","dedicator of cytokinesis 4","[DOCK4_HUMAN|Reviewed]RecName: Full=Dedicator of cytokinesis protein 4;+++[A0A024R749_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4, isoform CRA_a {ECO:0000313|EMBL:EAW83455.1};+++[A0A2X0SFR8_HUMAN|Unreviewed]SubName: Full=DOCK4 {ECO:0000313|EMBL:SPT35744.1}; Flags: Fragment;+++[A4D0S8_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:EAL24377.1};+++[C9J637_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406468}; Flags: Fragment;+++[C9J7D9_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406298}; Flags: Fragment;+++[C9JDB3_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000403504}; Flags: Fragment;+++[F5GXW1_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000440944};+++[F8WES4_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000393486};+++[H0Y599_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000397412}; Flags: Fragment;+++[H0Y7H7_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000412834}; Flags: Fragment;+++[Q149N2_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17695.1};+++[Q149N5_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17690.1};+++[Q149N6_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:AAI17689.1};+++[Q75MU6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DOCK4 {ECO:0000313|EMBL:AAS07431.1}; Flags: Fragment;"]
[9733,"'SART3'",579,519,513,537,null,"H00791///Disseminated superficial actinic porokeratosis (DSAP)",null,null,"GO:0071002///U4atac/U6atac snRNP+++GO:0061574///ASAP complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005691///U6atac snRNP+++GO:0015030///Cajal body+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0071001///U4/U6 snRNP","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0030624///U6atac snRNA binding+++GO:0003676///nucleic acid binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0030621///U4 snRNA binding+++GO:0017070///U6 snRNA binding","GO:0010468///regulation of gene expression+++GO:0000902///cell morphogenesis+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0048872///homeostasis of number of cells+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006334///nucleosome assembly+++GO:0000387///spliceosomal snRNP assembly+++GO:1903586///positive regulation of histone deubiquitination+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing","spliceosome associated factor 3, U4/U6 recycling protein","[SART3_HUMAN|Reviewed]RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000305}; Short=SART-3 {ECO:0000312|EMBL:BAA78384.1}; AltName: Full=Tat-interacting protein of 110 kDa {ECO:0000303|PubMed:11959860}; Short=Tip110 {ECO:0000303|PubMed:11959860}; AltName: Full=p110 nuclear RNA-binding protein {ECO:0000303|PubMed:12032085};+++[F8VV04_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449386}; Flags: Fragment;+++[F8VVK9_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449602}; Flags: Fragment;+++[F8VZM2_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447324}; Flags: Fragment;+++[F8W667_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000446577};+++[H0YHU8_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447875}; Flags: Fragment;"]
[9734,"'HDAC9'",1186,762.88,858,935.626666666667,"05034///Alcoholism+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0000118///histone deacetylase complex+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0035097///histone methyltransferase complex","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0071889///14-3-3 protein binding+++GO:0070491///repressing transcription factor binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0008134///transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0033558///protein deacetylase activity+++GO:0003682///chromatin binding+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding+++GO:0033613///activating transcription factor binding+++GO:0005080///protein kinase C binding+++GO:0003714///transcription corepressor activity+++GO:0016787///hydrolase activity","GO:0006954///inflammatory response+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0006325///chromatin organization+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0032703///negative regulation of interleukin-2 production+++GO:0042113///B cell activation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0007507///heart development+++GO:0032869///cellular response to insulin stimulus+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0030182///neuron differentiation+++GO:0007043///cell-cell junction assembly+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0001570///vasculogenesis+++GO:0030183///B cell differentiation+++GO:0001975///response to amphetamine+++GO:0034983///peptidyl-lysine deacetylation","histone deacetylase 9","[HDAC9_HUMAN|Reviewed]RecName: Full=Histone deacetylase 9; Short=HD9; EC=3.5.1.98; AltName: Full=Histone deacetylase 7B; Short=HD7; Short=HD7b; AltName: Full=Histone deacetylase-related protein; AltName: Full=MEF2-interacting transcription repressor MITR;+++[B5MCF1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000384017};+++[B7Z3P7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79008, highly similar to Histone deacetylase 9 {ECO:0000313|EMBL:BAH14480.1};+++[C9IZS0_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000412497}; Flags: Fragment;+++[C9J1W4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000392564}; Flags: Fragment;+++[C9J835_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000411422}; Flags: Fragment;+++[C9JD56_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000404763}; Flags: Fragment;+++[C9JLX1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000409003}; Flags: Fragment;+++[F8WDS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000415095};+++[Q75N08_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07409.1}; Flags: Fragment;+++[Q75N09_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07402.1}; Flags: Fragment;+++[Q75N10_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07401.1}; Flags: Fragment;+++[Q75N14_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07423.1}; Flags: Fragment;+++[Q75N15_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07424.1}; Flags: Fragment;+++[Q75N16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07422.1}; Flags: Fragment;+++[Q9Y6V1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAD15364.2};"]
[9735,"'KNTC1'",77,57,64,66,{"$nulls":4},"GO:0005829///cytosol+++GO:0005828///kinetochore microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:1990423///RZZ complex+++GO:0005856///cytoskeleton+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007096///regulation of exit from mitosis+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0051301///cell division","kinetochore associated 1","[KNTC1_HUMAN|Reviewed]RecName: Full=Kinetochore-associated protein 1; AltName: Full=Rough deal homolog; Short=HsROD; Short=Rod; Short=hRod;+++[E7ES84_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397992};+++[F5H5V0_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408760};+++[H0YFL5_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439119}; Flags: Fragment;+++[J3KQF2_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397140}; Flags: Fragment;"]
[9736,"'USP34'",1919,1416,1901,1745.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0004197///cysteine-type endopeptidase activity","GO:0071108///protein K48-linked deubiquitination+++GO:0006508///proteolysis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031647///regulation of protein stability+++GO:0016579///protein deubiquitination","ubiquitin specific peptidase 34","[UBP34_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 34; EC=3.4.19.12 {ECO:0000269|PubMed:14715245, ECO:0000269|PubMed:21383061}; AltName: Full=Deubiquitinating enzyme 34; AltName: Full=Ubiquitin thioesterase 34; AltName: Full=Ubiquitin-specific-processing protease 34;+++[A0A0C4DG73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000410559}; Flags: Fragment;+++[H7BZ73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000388129}; Flags: Fragment;+++[H7C150_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398489}; Flags: Fragment;+++[H7C183_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398960}; Flags: Fragment;"]
[9737,"'GPRASP1'",80,57,89,75.3333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0008333///endosome to lysosome transport+++GO:1990172///G protein-coupled receptor catabolic process","G protein-coupled receptor associated sorting protein 1","[GASP1_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 1; Short=GASP-1;"]
[9738,"'CCP110'",147,117,109,124.333333333333,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0030030///cell projection organization+++GO:0032465///regulation of cytokinesis+++GO:0007099///centriole replication+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0045724///positive regulation of cilium assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1902018///negative regulation of cilium assembly+++GO:0016579///protein deubiquitination+++GO:0051298///centrosome duplication+++GO:0032053///ciliary basal body organization","centriolar coiled-coil protein 110","[CP110_HUMAN|Reviewed]RecName: Full=Centriolar coiled-coil protein of 110 kDa; AltName: Full=Centrosomal protein of 110 kDa; Short=CP110; Short=Cep110;+++[A0A024QYV8_HUMAN|Unreviewed]SubName: Full=CP110 protein, isoform CRA_a {ECO:0000313|EMBL:EAW50288.1};+++[H3BMS1_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000454514}; Flags: Fragment;+++[H3BVH3_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000458123};+++[I3L262_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000459410}; Flags: Fragment;"]
[9739,"'SETD1A'",1124,1119,1098,1113.66666666667,"00310///Lysine degradation",null,null,"R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine","GO:0048188///Set1C/COMPASS complex+++GO:0016607///nuclear speck+++GO:0000790///nuclear chromatin+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0016740///transferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008013///beta-catenin binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008134///transcription factor binding","GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0032259///methylation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:1902275///regulation of chromatin organization+++GO:0051568///histone H3-K4 methylation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization","SET domain containing 1A","[SET1A_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETD1A; EC=2.1.1.43; AltName: Full=Lysine N-methyltransferase 2F; AltName: Full=SET domain-containing protein 1A; Short=hSET1A; AltName: Full=Set1/Ash2 histone methyltransferase complex subunit SET1;+++[C9J2Z9_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETD1A {ECO:0000313|Ensembl:ENSP00000391408}; Flags: Fragment;+++[L0R6N9_HUMAN|Unreviewed]SubName: Full=Alternative protein SETD1A {ECO:0000313|EMBL:CCO13810.1};"]
[974,"'CD79B'",6,2,7,5,"04662///B cell receptor signaling pathway","H00085///Agammaglobulinemias",null,null,"GO:0009897///external side of plasma membrane+++GO:0019815///B cell receptor complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0004888///transmembrane signaling receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0002376///immune system process+++GO:0051260///protein homooligomerization+++GO:0050853///B cell receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0002250///adaptive immune response","CD79b molecule","[CD79B_HUMAN|Reviewed]RecName: Full=B-cell antigen receptor complex-associated protein beta chain; AltName: Full=B-cell-specific glycoprotein B29; AltName: Full=Ig-beta; AltName: Full=Immunoglobulin-associated B29 protein; AltName: CD_antigen=CD79b; Flags: Precursor;+++[A0A192GQF2_HUMAN|Unreviewed]SubName: Full=B-cell antigen receptor complex-associated protein beta chain isoform 3 {ECO:0000313|EMBL:ANK58153.1}; Flags: Fragment;+++[Q6PIS4_HUMAN|Unreviewed]SubName: Full=CD79B protein {ECO:0000313|EMBL:AAH30210.1};"]
[9741,"'LAPTM4A'",4319,4370,4309,4332.66666666667,"04142///Lysosome",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding",null,"lysosomal protein transmembrane 4 alpha","[LAP4A_HUMAN|Reviewed]RecName: Full=Lysosomal-associated transmembrane protein 4A; AltName: Full=Golgi 4-transmembrane-spanning transporter MTP;+++[Q4ZG00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAX88938.1}; Flags: Fragment;+++[Q53QZ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAY24172.1}; Flags: Fragment;+++[Q6IBP4_HUMAN|Unreviewed]SubName: Full=LAPTM4A protein {ECO:0000313|EMBL:CAG33039.1}; SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH93075.1}; SubName: Full=Lysosomal-associated protein transmembrane 4 alpha, isoform CRA_b {ECO:0000313|EMBL:EAX00834.1};+++[Q9BTU8_HUMAN|Unreviewed]SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH03158.1};"]
[9742,"'IFT140'",622,584,614,606.666666666667,null,"H02157///Short-rib thoracic dysplasia",null,null,"GO:0005737///cytoplasm+++GO:0097730///non-motile cilium+++GO:0005929///cilium+++GO:0097542///ciliary tip+++GO:0036064///ciliary basal body+++GO:0030991///intraciliary transport particle A+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0032391///photoreceptor connecting cilium+++GO:0005930///axoneme+++GO:0001750///photoreceptor outer segment+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0003674///molecular_function","GO:0035721///intraciliary retrograde transport+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1990403///embryonic brain development+++GO:0035108///limb morphogenesis+++GO:0008589///regulation of smoothened signaling pathway+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0021532///neural tube patterning+++GO:0007368///determination of left/right symmetry+++GO:1905515///non-motile cilium assembly+++GO:0048705///skeletal system morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0035845///photoreceptor cell outer segment organization+++GO:1902017///regulation of cilium assembly+++GO:0030030///cell projection organization+++GO:0042733///embryonic digit morphogenesis+++GO:0060041///retina development in camera-type eye+++GO:0007507///heart development+++GO:0031076///embryonic camera-type eye development+++GO:0072001///renal system development","intraflagellar transport 140","[IF140_HUMAN|Reviewed]RecName: Full=Intraflagellar transport protein 140 homolog; AltName: Full=WD and tetratricopeptide repeats protein 2;+++[H3BNC5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000454781}; Flags: Fragment;+++[H3BTA5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000457092}; Flags: Fragment;+++[I3L0Y8_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000458439}; Flags: Fragment;+++[J3KPW0_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000380562};+++[Q96RY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein gs114 {ECO:0000313|EMBL:AAK61287.1};"]
[9743,"'ARHGAP32'",301,247,312,286.666666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0015629///actin cytoskeleton+++GO:0005783///endoplasmic reticulum+++GO:0014069///postsynaptic density+++GO:0005789///endoplasmic reticulum membrane+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0001650///fibrillar center","GO:0035091///phosphatidylinositol binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 32","[RHG32_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 32; AltName: Full=Brain-specific Rho GTPase-activating protein; AltName: Full=GAB-associated Cdc42/Rac GTPase-activating protein; AltName: Full=GC-GAP; AltName: Full=GTPase regulator interacting with TrkA; AltName: Full=Rho-type GTPase-activating protein 32; AltName: Full=Rho/Cdc42/Rac GTPase-activating protein RICS; AltName: Full=RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; AltName: Full=p200RhoGAP; AltName: Full=p250GAP;+++[A0A024R3K8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_c {ECO:0000313|EMBL:EAW67737.1};+++[A0A024R3N1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_a {ECO:0000313|EMBL:EAW67733.1};+++[A0A2X0SFD0_HUMAN|Unreviewed]SubName: Full=ARHGAP32 {ECO:0000313|EMBL:SPT35703.1}; Flags: Fragment;+++[E9PRH3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432303}; Flags: Fragment;+++[G3V174_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432468}; SubName: Full=Rho GTPase-activating protein, isoform CRA_b {ECO:0000313|EMBL:EAW67734.1};+++[Q86T64_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451F1115 {ECO:0000313|EMBL:CAD89974.1}; Flags: Fragment;+++[Q86UT2_HUMAN|Unreviewed]SubName: Full=RICS protein {ECO:0000313|EMBL:AAH51236.1}; Flags: Fragment;"]
[9744,"'ACAP1'",41.57,47.52,39.89,42.9933333333333,"04144///Endocytosis",{"$nulls":3},"GO:0055038///recycling endosome membrane+++GO:0005768///endosome+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity+++GO:0015031///protein transport","ArfGAP with coiled-coil, ankyrin repeat and PH domains 1","[ACAP1_HUMAN|Reviewed]RecName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; AltName: Full=Centaurin-beta-1; Short=Cnt-b1;+++[I3L0K9_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000458173}; Flags: Fragment;+++[I3L268_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459422}; Flags: Fragment;"]
[9745,"'ZNF536'",298,218,294,270,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0045665///negative regulation of neuron differentiation+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger protein 536","[ZN536_HUMAN|Reviewed]RecName: Full=Zinc finger protein 536;+++[A7E228_HUMAN|Unreviewed]SubName: Full=ZNF536 protein {ECO:0000313|EMBL:AAI50172.1};+++[K7EJP8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465268}; Flags: Fragment;+++[K7EKT4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465771}; Flags: Fragment;+++[K7EQN6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000467909}; Flags: Fragment;"]
[9746,"'CLSTN3'",4311,4252,4006,4189.66666666667,{"$nulls":4},"GO:0099061///integral component of postsynaptic density membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0098982///GABA-ergic synapse+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0098978///glutamatergic synapse+++GO:0014069///postsynaptic density","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051965///positive regulation of synapse assembly+++GO:0051932///synaptic transmission, GABAergic+++GO:1905606///regulation of presynapse assembly+++GO:0001558///regulation of cell growth+++GO:0050806///positive regulation of synaptic transmission+++GO:1902474///positive regulation of protein localization to synapse+++GO:0007155///cell adhesion+++GO:0007416///synapse assembly+++GO:0035249///synaptic transmission, glutamatergic","calsyntenin 3","[CSTN3_HUMAN|Reviewed]RecName: Full=Calsyntenin-3; AltName: Full=Alcadein-beta; Short=Alc-beta; Flags: Precursor;+++[F5H172_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443959}; Flags: Fragment;+++[F5H5C6_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443490}; Flags: Fragment;+++[F5H5D7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443468}; Flags: Fragment;+++[F5H746_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442801}; Flags: Fragment;+++[F5H7C7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442612}; Flags: Fragment;+++[Q8IUW6_HUMAN|Unreviewed]SubName: Full=CLSTN3 protein {ECO:0000313|EMBL:AAH39075.1};"]
[9747,"'TCAF1'",2875,2398,2279,2517.33333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0044325///ion channel binding","GO:1901529///positive regulation of anion channel activity+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0030336///negative regulation of cell migration","TRPM8 channel associated factor 1","[TCAF1_HUMAN|Reviewed]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[B4DST7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58406, weakly similar to Mus musculus experimental autoimmune prostatitis antigen 2 (Eapa2), mRNA {ECO:0000313|EMBL:BAG61749.1};+++[C9J648_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000418432}; Flags: Fragment;+++[C9J9F4_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000417600}; Flags: Fragment;+++[C9JD13_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000420607}; Flags: Fragment;+++[C9K0E7_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000419622}; Flags: Fragment;"]
[9748,"'SLK'",1172,726,962,953.333333333333,"04114///Oocyte meiosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0031252///cell leading edge","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0042802///identical protein binding","GO:0030334///regulation of cell migration+++GO:0023014///signal transduction by protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031122///cytoplasmic microtubule organization+++GO:0006915///apoptotic process+++GO:0051893///regulation of focal adhesion assembly+++GO:0007346///regulation of mitotic cell cycle+++GO:0032147///activation of protein kinase activity","STE20 like kinase","[SLK_HUMAN|Reviewed]RecName: Full=STE20-like serine/threonine-protein kinase; Short=STE20-like kinase; Short=hSLK; EC=2.7.11.1; AltName: Full=CTCL tumor antigen se20-9; AltName: Full=STE20-related serine/threonine-protein kinase; Short=STE20-related kinase; AltName: Full=Serine/threonine-protein kinase 2;+++[L8ECF1_HUMAN|Unreviewed]SubName: Full=Alternative protein SLK {ECO:0000313|EMBL:CCQ43457.1};"]
[9749,"'PHACTR2'",1112.04,617.01,758,829.016666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031092///platelet alpha granule membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0004864///protein phosphatase inhibitor activity","GO:0002576///platelet degranulation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","phosphatase and actin regulator 2","[PHAR2_HUMAN|Reviewed]RecName: Full=Phosphatase and actin regulator 2;+++[F5H858_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[F6TH74_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[H9KVA6_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};+++[J3KP75_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};"]
[975,"'CD81'",11529,13615,11111,12085,"05144///Malaria+++04662///B cell receptor signaling pathway+++05160///Hepatitis C","H00088///Common variable immunodeficiency (CVID)",null,null,"GO:0001772///immunological synapse+++GO:0031982///vesicle+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005925///focal adhesion","GO:0001618///virus receptor activity+++GO:0023026///MHC class II protein complex binding+++GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:1990459///transferrin receptor binding","GO:0008284///positive regulation of cell proliferation+++GO:0046718///viral entry into host cell+++GO:0061462///protein localization to lysosome+++GO:0031647///regulation of protein stability+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000145///regulation of cell motility+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:0008104///protein localization+++GO:0050776///regulation of immune response+++GO:0030449///regulation of complement activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000187///activation of MAPK activity+++GO:0031623///receptor internalization+++GO:0008283///cell proliferation+++GO:0016032///viral process+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0043128///positive regulation of 1-phosphatidylinositol 4-kinase activity+++GO:0030890///positive regulation of B cell proliferation+++GO:1904352///positive regulation of protein catabolic process in the vacuole+++GO:0007166///cell surface receptor signaling pathway","CD81 molecule","[CD81_HUMAN|Reviewed]RecName: Full=CD81 antigen; AltName: Full=26 kDa cell surface protein TAPA-1; AltName: Full=Target of the antiproliferative antibody 1; AltName: Full=Tetraspanin-28; Short=Tspan-28; AltName: CD_antigen=CD81;+++[A0A024RCB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[A6NMH8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PIF1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJK1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PM31_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000433178}; Flags: Fragment;+++[E9PPF5_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432723}; Flags: Fragment;+++[E9PQV4_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432497}; Flags: Fragment;+++[E9PRJ8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDJ9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDL9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YEE2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[9750,"'RIPOR2'",6,1,2,3,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0060171///stereocilium membrane+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0032420///stereocilium","GO:0071889///14-3-3 protein binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0071158///positive regulation of cell cycle arrest+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0007605///sensory perception of sound+++GO:1903904///negative regulation of establishment of T cell polarity+++GO:0071260///cellular response to mechanical stimulus+++GO:2000405///negative regulation of T cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0051491///positive regulation of filopodium assembly+++GO:0045663///positive regulation of myoblast differentiation+++GO:0006935///chemotaxis+++GO:1905872///negative regulation of protein localization to cell leading edge+++GO:0042130///negative regulation of T cell proliferation+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:2001107///negative regulation of Rho guanyl-nucleotide exchange factor activity+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0009968///negative regulation of signal transduction+++GO:0048741///skeletal muscle fiber development+++GO:1901741///positive regulation of myoblast fusion+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0030154///cell differentiation+++GO:0045184///establishment of protein localization+++GO:2000114///regulation of establishment of cell polarity+++GO:1990869///cellular response to chemokine+++GO:0051260///protein homooligomerization+++GO:1901673///regulation of mitotic spindle assembly+++GO:0090023///positive regulation of neutrophil chemotaxis","RHO family interacting cell polarization regulator 2","[RIPR2_HUMAN|Reviewed]RecName: Full=Rho family-interacting cell polarization regulator 2;+++[A0A024QZY9_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_c {ECO:0000313|EMBL:EAW55471.1};+++[A0A024R028_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_a {ECO:0000313|EMBL:EAW55469.1};+++[A0A2R8Y4B9_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493881}; Flags: Fragment;+++[A0A2R8Y4N2_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493948}; Flags: Fragment;+++[A0A2R8Y7B3_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000495879};+++[A0A2R8YEE0_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494268};+++[A0A2R8YF77_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494904};+++[B7Z5J9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56137 {ECO:0000313|EMBL:BAH12935.1};+++[B7Z6D6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60883 {ECO:0000313|EMBL:BAH13222.1};+++[B7Z6U4_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441305}; SubName: Full=cDNA FLJ56038 {ECO:0000313|EMBL:BAH13380.1};+++[F5GX51_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441138};+++[F5H029_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000438425};"]
[9751,"'SNPH'",275,308,249,277.333333333333,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0005881///cytoplasmic microtubule+++GO:0042734///presynaptic membrane+++GO:0016021///integral component of membrane","GO:0017075///syntaxin-1 binding","GO:0016081///synaptic vesicle docking+++GO:0007269///neurotransmitter secretion+++GO:0030182///neuron differentiation+++GO:0007420///brain development","syntaphilin","[SNPH_HUMAN|Reviewed]RecName: Full=Syntaphilin;"]
[9752,"'PCDHA9'",13.82,7.41,6.3,9.17666666666667,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","protocadherin alpha 9","[PCDA9_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-9; Short=PCDH-alpha-9; Flags: Precursor;"]
[9753,"'ZSCAN12'",138,69.99,113.05,107.013333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and SCAN domain containing 12","[ZSC12_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 12; AltName: Full=Zinc finger protein 305; AltName: Full=Zinc finger protein 96;+++[A0A024RCI2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 96, isoform CRA_a {ECO:0000313|EMBL:EAX03162.1};"]
[9754,"'STARD8'",38,33,37,36,{"$nulls":4},"GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0008289///lipid binding","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity","StAR related lipid transfer domain containing 8","[STAR8_HUMAN|Reviewed]RecName: Full=StAR-related lipid transfer protein 8; AltName: Full=Deleted in liver cancer 3 protein; Short=DLC-3; AltName: Full=START domain-containing protein 8; Short=StARD8; AltName: Full=START-GAP3;+++[A0A2X0U2P1_HUMAN|Unreviewed]SubName: Full=STARD8 {ECO:0000313|EMBL:SPT35801.1}; Flags: Fragment;+++[E5RFN7_HUMAN|Unreviewed]SubName: Full=StAR-related lipid transfer protein 8 {ECO:0000313|Ensembl:ENSP00000428031};"]
[9755,"'TBKBP1'",513,505,545,521,"04622///RIG-I-like receptor signaling pathway",{"$nulls":4},"GO:0005515///protein binding","GO:0002376///immune system process+++GO:0016032///viral process+++GO:0045087///innate immune response","TBK1 binding protein 1","[TBKB1_HUMAN|Reviewed]RecName: Full=TANK-binding kinase 1-binding protein 1; Short=TBK1-binding protein 1;+++[D3DTT5_HUMAN|Unreviewed]SubName: Full=TBK1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94806.1};+++[F5H1U4_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000446365}; Flags: Fragment;+++[J3KS71_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000462339}; Flags: Fragment;"]
[9757,"'KMT2B'",1095,1073,1166,1111.33333333333,"00310///Lysine degradation","H01613///Follicular lymphoma+++H00831///Primary dystonia",null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008168///methyltransferase activity","GO:0051568///histone H3-K4 methylation+++GO:0032259///methylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0009994///oocyte differentiation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization+++GO:0016458///gene silencing+++GO:0007613///memory+++GO:0080182///histone H3-K4 trimethylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0030728///ovulation","lysine methyltransferase 2B","[KMT2B_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase 2B; Short=Lysine N-methyltransferase 2B; EC=2.1.1.43; AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 4; AltName: Full=Trithorax homolog 2; AltName: Full=WW domain-binding protein 7; Short=WBP-7;"]
[9758,"'FRMPD4'",5,0,1,2,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine","GO:0008289///lipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005515///protein binding","GO:0051835///positive regulation of synapse structural plasticity+++GO:0098974///postsynaptic actin cytoskeleton organization","FERM and PDZ domain containing 4","[FRPD4_HUMAN|Reviewed]RecName: Full=FERM and PDZ domain-containing protein 4; AltName: Full=PDZ domain-containing protein 10; AltName: Full=PSD-95-interacting regulator of spine morphogenesis; Short=Preso;+++[A0A087WYX8_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000482182};+++[A0A1W2PQW0_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000492353}; Flags: Fragment;+++[B7ZLE1_HUMAN|Unreviewed]SubName: Full=FRMPD4 protein {ECO:0000313|EMBL:AAI43747.1};"]
[9759,"'HDAC4'",167,124,131.94,140.98,"05203///Viral carcinogenesis+++05034///Alcoholism+++05169///Epstein-Barr virus infection+++05165///Human papillomavirus infection+++04371///Apelin signaling pathway","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0017053///transcriptional repressor complex+++GO:0005654///nucleoplasm+++GO:0042641///actomyosin+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0031672///A band+++GO:0030018///Z disc+++GO:0031594///neuromuscular junction+++GO:0030017///sarcomere+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:1990841///promoter-specific chromatin binding+++GO:0004407///histone deacetylase activity+++GO:0042826///histone deacetylase binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033613///activating transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0008270///zinc ion binding+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0030955///potassium ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003714///transcription corepressor activity+++GO:0070491///repressing transcription factor binding+++GO:0033558///protein deacetylase activity+++GO:0005515///protein binding+++GO:0001085///RNA polymerase II transcription factor binding","GO:0006954///inflammatory response+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0040029///regulation of gene expression, epigenetic+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0033235///positive regulation of protein sumoylation+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0030183///B cell differentiation+++GO:0006338///chromatin remodeling+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070555///response to interleukin-1+++GO:0008284///positive regulation of cell proliferation+++GO:0001501///skeletal system development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0002076///osteoblast development+++GO:0006476///protein deacetylation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0042113///B cell activation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0007399///nervous system development+++GO:0045820///negative regulation of glycolytic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0043393///regulation of protein binding+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0016575///histone deacetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0006325///chromatin organization+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010832///negative regulation of myotube differentiation","histone deacetylase 4","[HDAC4_HUMAN|Reviewed]RecName: Full=Histone deacetylase 4; Short=HD4; EC=3.5.1.98;+++[C9J0X4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000392912}; Flags: Fragment;+++[C9J481_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000405226}; Flags: Fragment;+++[F5H0B1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000438111}; Flags: Fragment;+++[H7BZT3_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000391226}; Flags: Fragment;+++[H7C397_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000410551}; Flags: Fragment;"]
[976,"'ADGRE5'",61,77,61.99,66.6633333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0030667///secretory granule membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007267///cell-cell signaling+++GO:0007155///cell adhesion+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0043312///neutrophil degranulation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor E5","[CD97_HUMAN|Reviewed]RecName: Full=CD97 antigen; AltName: Full=Leukocyte antigen CD97; AltName: CD_antigen=CD97; Contains: RecName: Full=CD97 antigen subunit alpha; Contains: RecName: Full=CD97 antigen subunit beta; Flags: Precursor;+++[K7EKV5_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000465800}; Flags: Fragment;+++[K7EPE8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467351}; Flags: Fragment;+++[K7EPP8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467478}; Flags: Fragment;"]
[9760,"'TOX'",815,733,699,749,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0048535///lymph node development+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030098///lymphocyte differentiation+++GO:0048541///Peyer's patch development","thymocyte selection associated high mobility group box","[TOX_HUMAN|Reviewed]RecName: Full=Thymocyte selection-associated high mobility group box protein TOX; AltName: Full=Thymus high mobility group box protein TOX;"]
[9761,"'MLEC'",4512,3786,3927.18,4075.06,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0035579///specific granule membrane+++GO:0005886///plasma membrane","GO:0019899///enzyme binding+++GO:0030246///carbohydrate binding","GO:0005975///carbohydrate metabolic process+++GO:0043312///neutrophil degranulation+++GO:0006457///protein folding","malectin","[MLEC_HUMAN|Reviewed]RecName: Full=Malectin; Flags: Precursor;+++[F5GX14_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000440746};+++[F5H1S8_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000438950}; Flags: Fragment;+++[H0YG07_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000441247}; Flags: Fragment;"]
[9762,"'LZTS3'",264,283,257,268,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density",null,"GO:0061001///regulation of dendritic spine morphogenesis","leucine zipper tumor suppressor family member 3","[LZTS3_HUMAN|Reviewed]RecName: Full=Leucine zipper putative tumor suppressor 3 {ECO:0000305}; AltName: Full=ProSAP-interacting protein 1 {ECO:0000250|UniProtKB:Q8K1Q4}; Short=ProSAPiP1 {ECO:0000250|UniProtKB:Q8K1Q4};"]
[9764,"'KIAA0513'",392,270,344.8,335.6,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm",null,null,"KIAA0513","[K0513_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0513;+++[H3BMU3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454547}; Flags: Fragment;+++[H3BNA7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454758}; Flags: Fragment;"]
[9765,"'ZFYVE16'",186,148,181,171.666666666667,"04350///TGF-beta signaling pathway+++04144///Endocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm","GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0046872///metal ion binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding","GO:0016050///vesicle organization+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0030509///BMP signaling pathway+++GO:0016197///endosomal transport+++GO:0006622///protein targeting to lysosome","zinc finger FYVE-type containing 16","[ZFY16_HUMAN|Reviewed]RecName: Full=Zinc finger FYVE domain-containing protein 16; AltName: Full=Endofin; AltName: Full=Endosome-associated FYVE domain protein;+++[A0A024RAL3_HUMAN|Unreviewed]RecName: Full=Zinc finger FYVE domain-containing protein {ECO:0000256|PIRNR:PIRNR037289};+++[D6RC80_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000422356}; Flags: Fragment;+++[H0Y8R0_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000421785}; Flags: Fragment;+++[H0YAA4_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426500}; Flags: Fragment;+++[H0YAB1_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426536}; Flags: Fragment;"]
[9766,"'SUSD6'",518,523,501,514,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0008219///cell death","sushi domain containing 6","[SUSD6_HUMAN|Reviewed]RecName: Full=Sushi domain-containing protein 6 {ECO:0000312|HGNC:HGNC:19956}; AltName: Full=Drug-activated gene overexpressed protein {ECO:0000303|PubMed:24652652}; Flags: Precursor;"]
[9767,"'JADE3'",82,65,78,75,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000123///histone acetyltransferase complex","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0043981///histone H4-K5 acetylation+++GO:0043966///histone H3 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0043982///histone H4-K8 acetylation","jade family PHD finger 3","[JADE3_HUMAN|Reviewed]RecName: Full=Protein Jade-3; AltName: Full=Jade family PHD finger protein 3; AltName: Full=PHD finger protein 16;+++[A0A024R1A2_HUMAN|Unreviewed]SubName: Full=PHD finger protein 16, isoform CRA_a {ECO:0000313|EMBL:EAW59278.1};+++[F2Z2B6_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000400584}; Flags: Fragment;+++[F2Z3N8_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000391009}; Flags: Fragment;"]
[9768,"'PCLAF'",6.93,1.03,1.09,3.01666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0003682///chromatin binding","GO:0006260///DNA replication+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0007098///centrosome cycle+++GO:0006281///DNA repair+++GO:0019985///translesion synthesis","PCNA clamp associated factor","[PAF15_HUMAN|Reviewed]RecName: Full=PCNA-associated factor {ECO:0000305}; AltName: Full=Hepatitis C virus NS5A-transactivated protein 9; Short=HCV NS5A-transactivated protein 9; AltName: Full=Overexpressed in anaplastic thyroid carcinoma 1; Short=OEATC-1; AltName: Full=PCNA-associated factor of 15 kDa; Short=PAF15; Short=p15PAF; AltName: Full=PCNA-clamp-associated factor {ECO:0000312|HGNC:HGNC:28961};+++[G9G6C4_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89543.1}; Flags: Fragment;+++[G9G6D7_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89556.1}; Flags: Fragment;+++[G9G6H1_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89590.1}; Flags: Fragment;+++[H0YKX3_HUMAN|Unreviewed]SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000452975};+++[H0YMA4_HUMAN|Unreviewed]SubName: Full=HCG2039386, isoform CRA_b {ECO:0000313|EMBL:EAW77680.1}; SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000453527};"]
[977,"'CD151'",17409,19971,15797,17725.6666666667,null,"H00928///Nephropathy with pretibial epidermolysis bullosa and deafness",null,null,"GO:0009986///cell surface+++GO:0005925///focal adhesion+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005604///basement membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005178///integrin binding","GO:0044319///wound healing, spreading of cells+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0031581///hemidesmosome assembly+++GO:0016477///cell migration+++GO:0045807///positive regulation of endocytosis+++GO:0030335///positive regulation of cell migration+++GO:0042098///T cell proliferation","CD151 molecule (Raph blood group)","[CD151_HUMAN|Reviewed]RecName: Full=CD151 antigen; AltName: Full=GP27; AltName: Full=Membrane glycoprotein SFA-1; AltName: Full=Platelet-endothelial tetraspan antigen 3; Short=PETA-3; AltName: Full=Tetraspanin-24; Short=Tspan-24; AltName: CD_antigen=CD151;+++[A0A024RCB3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJC8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PJE8_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000433752}; Flags: Fragment;+++[E9PK37_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000431671}; Flags: Fragment;+++[E9PLZ6_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PMR4_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PP93_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000434663}; Flags: Fragment;+++[E9PRJ3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PSA1_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000435854}; Flags: Fragment;+++[K4DIA7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[K4DIB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[Q6ZNZ0_HUMAN|Unreviewed]SubName: Full=CD151 antigen (Raph blood group), isoform CRA_b {ECO:0000313|EMBL:EAX02401.1}; SubName: Full=cDNA FLJ26859 fis, clone PRS08290 {ECO:0000313|EMBL:BAC85335.1};"]
[9770,"'RASSF2'",1042,739,830,870.333333333333,"04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species",{"$nulls":3},"GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0000777///condensed chromosome kinetochore","GO:0004672///protein kinase activity+++GO:0005515///protein binding","GO:0038168///epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade+++GO:0001501///skeletal system development+++GO:0042981///regulation of apoptotic process+++GO:0046849///bone remodeling+++GO:0045670///regulation of osteoclast differentiation+++GO:0001503///ossification+++GO:0050821///protein stabilization+++GO:0046330///positive regulation of JNK cascade+++GO:0007049///cell cycle+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:0048872///homeostasis of number of cells+++GO:0006468///protein phosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0045667///regulation of osteoblast differentiation+++GO:0007165///signal transduction+++GO:0043065///positive regulation of apoptotic process","Ras association domain family member 2","[RASF2_HUMAN|Reviewed]RecName: Full=Ras association domain-containing protein 2;"]
[9771,"'RAPGEF5'",63,55,68,62,"04015///Rap1 signaling pathway+++04014///Ras signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0030742///GTP-dependent protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0017034///Rap guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0035556///intracellular signal transduction+++GO:0007399///nervous system development+++GO:0007264///small GTPase mediated signal transduction","Rap guanine nucleotide exchange factor 5","[RPGF5_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 5; AltName: Full=Guanine nucleotide exchange factor for Rap1; AltName: Full=M-Ras-regulated Rap GEF; Short=MR-GEF; AltName: Full=Related to Epac; Short=Repac;+++[A0A0S2Z561_HUMAN|Unreviewed]SubName: Full=HCG38228, isoform CRA_b {ECO:0000313|EMBL:EAW93746.1}; SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 2 {ECO:0000313|EMBL:ALQ33949.1}; Flags: Fragment;+++[A0A0S2Z5S1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 1 {ECO:0000313|EMBL:ALQ33948.1}; Flags: Fragment;+++[A8MQ07_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000343656};+++[C9JBS6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000415664}; Flags: Fragment;+++[C9JHM4_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000395729}; Flags: Fragment;+++[E9PGY3_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000384870};+++[F8WD32_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000403956};+++[Q5JPD2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667A016 {ECO:0000313|EMBL:CAI46177.1};"]
[9772,"'TMEM94'",2002,1969,2372,2114.33333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 94","[TMM94_HUMAN|Reviewed]RecName: Full=Transmembrane protein 94 {ECO:0000312|HGNC:HGNC:28983};+++[A0A024R8S6_HUMAN|Unreviewed]SubName: Full=KIAA0195, isoform CRA_a {ECO:0000313|EMBL:EAW89275.1};+++[B7Z9U5_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78959, highly similar to Transmembrane protein 94 {ECO:0000313|EMBL:BAH14431.1};+++[C9JL75_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000364397};+++[J3KRN3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462084}; Flags: Fragment;+++[J3KRU7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462170}; Flags: Fragment;+++[J3KS76_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462344};+++[J3KT63_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462821}; Flags: Fragment;+++[J3KTL5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463046}; Flags: Fragment;+++[J3QLC5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463487}; Flags: Fragment;+++[J3QLM7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463620}; Flags: Fragment;+++[J3QQW3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463929};+++[J3QRT3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464370}; Flags: Fragment;+++[J3QRT7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464375}; Flags: Fragment;+++[J3QRY7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464437}; Flags: Fragment;+++[J3QS17_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464479}; Flags: Fragment;+++[J3QS24_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464491}; Flags: Fragment;+++[J3QSG7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464679}; Flags: Fragment;"]
[9774,"'BCLAF1'",1762,1126,1226,1371.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:1990830///cellular response to leukemia inhibitory factor+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0043065///positive regulation of apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006915///apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2001022///positive regulation of response to DNA damage stimulus","BCL2 associated transcription factor 1","[BCLF1_HUMAN|Reviewed]RecName: Full=Bcl-2-associated transcription factor 1; Short=Btf; AltName: Full=BCLAF1 and THRAP3 family member 1;+++[A0A1W2PQ43_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000491530};+++[E9PJA7_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433822};+++[E9PK09_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000431734}; Flags: Fragment;+++[E9PK91_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000435441};+++[E9PKI6_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433505};+++[E9PQN2_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436142};+++[H0YF00_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436913}; Flags: Fragment;+++[H0YF14_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437018}; Flags: Fragment;+++[H0YF63_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437333}; Flags: Fragment;+++[Q6DCA8_HUMAN|Unreviewed]SubName: Full=BCLAF1 protein {ECO:0000313|EMBL:AAH78160.1}; Flags: Fragment;"]
[9775,"'EIF4A3'",391,471,417,426.333333333333,"03013///RNA transport+++03015///mRNA surveillance pathway+++03040///Spliceosome",null,"M00430///Exon junction complex (EJC)",null,"GO:0016607///nuclear speck+++GO:1990904///ribonucleoprotein complex+++GO:0043025///neuronal cell body+++GO:0071013///catalytic step 2 spliceosome+++GO:0099524///postsynaptic cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex+++GO:0005681///spliceosomal complex+++GO:0030425///dendrite+++GO:0005634///nucleus","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0008143///poly(A) binding+++GO:0003729///mRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0000166///nucleotide binding","GO:0006364///rRNA processing+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0072715///cellular response to selenite ion+++GO:0035640///exploration behavior+++GO:1902415///regulation of mRNA binding+++GO:0045727///positive regulation of translation+++GO:1904570///negative regulation of selenocysteine incorporation+++GO:0008306///associative learning+++GO:0006406///mRNA export from nucleus+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:1904574///negative regulation of selenocysteine insertion sequence binding+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0008380///RNA splicing+++GO:0031124///mRNA 3'-end processing+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0014070///response to organic cyclic compound+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0010629///negative regulation of gene expression+++GO:0051028///mRNA transport","eukaryotic translation initiation factor 4A3","[IF4A3_HUMAN|Reviewed]RecName: Full=Eukaryotic initiation factor 4A-III; Short=eIF-4A-III; Short=eIF4A-III; EC=3.6.4.13 {ECO:0000269|PubMed:16170325, ECO:0000269|PubMed:17375189, ECO:0000269|PubMed:22961380}; AltName: Full=ATP-dependent RNA helicase DDX48; AltName: Full=ATP-dependent RNA helicase eIF4A-3; AltName: Full=DEAD box protein 48; AltName: Full=Eukaryotic initiation factor 4A-like NUK-34; AltName: Full=Eukaryotic translation initiation factor 4A isoform 3; AltName: Full=Nuclear matrix protein 265; Short=NMP 265; Short=hNMP 265; Contains: RecName: Full=Eukaryotic initiation factor 4A-III, N-terminally processed;+++[A0A024R8W0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 48, isoform CRA_a {ECO:0000313|EMBL:EAW89585.1};+++[I3L3H2_HUMAN|Unreviewed]SubName: Full=Eukaryotic initiation factor 4A-III {ECO:0000313|Ensembl:ENSP00000460439}; Flags: Fragment;"]
[9776,"'ATG13'",2692,2576,2618,2628.66666666667,"04138///Autophagy - yeast+++04136///Autophagy - other+++04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0019898///extrinsic component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane","GO:0019887///protein kinase regulator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0098780///response to mitochondrial depolarisation+++GO:0000422///autophagy of mitochondrion+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0000045///autophagosome assembly+++GO:0016241///regulation of macroautophagy+++GO:0006914///autophagy+++GO:0000423///mitophagy+++GO:0034497///protein localization to phagophore assembly site+++GO:0032147///activation of protein kinase activity+++GO:0016236///macroautophagy","autophagy related 13","[ATG13_HUMAN|Reviewed]RecName: Full=Autophagy-related protein 13;+++[A0A1B0GXJ3_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463808}; Flags: Fragment;+++[A8K0S6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214};+++[E9PPR2_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;+++[H0YCL5_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000431877}; Flags: Fragment;+++[H0YDR0_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000434125}; Flags: Fragment;+++[H0YEM7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000436174}; Flags: Fragment;+++[H0YF43_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000437191}; Flags: Fragment;+++[J3KRU6_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462167}; Flags: Fragment;+++[J3KST9_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462644}; Flags: Fragment;+++[J3QLH7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463550}; Flags: Fragment;+++[J3QR16_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463998}; Flags: Fragment;+++[J3QR83_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464091}; Flags: Fragment;+++[J3QRL1_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464274}; Flags: Fragment;+++[J9JIF6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;"]
[9777,"'TM9SF4'",1948,1912,1938,1932.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04062///Chemokine signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005768///endosome+++GO:0005769///early endosome","GO:0005515///protein binding","GO:0006909///phagocytosis+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0072657///protein localization to membrane+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0051453///regulation of intracellular pH+++GO:0007155///cell adhesion+++GO:0001666///response to hypoxia","transmembrane 9 superfamily member 4","[TM9S4_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 4; AltName: Full=Tumor cannibalism associated protein 1 {ECO:0000303|PubMed:19893578}; Flags: Precursor;+++[A0A024QYR3_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[A0A0C4DFM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[B4DH88_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F2Z2L1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F8WCN2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[9778,"'KIAA0232'",790,434,503,575.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0000166///nucleotide binding+++GO:0005524///ATP binding",null,"KIAA0232","[K0232_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0232;+++[A5YKK5_HUMAN|Unreviewed]SubName: Full=KIAA0232 {ECO:0000313|EMBL:ABQ66267.1};+++[D6REK0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0232 {ECO:0000313|Ensembl:ENSP00000426815};+++[Q9Y349_HUMAN|Unreviewed]SubName: Full=KIAA0232 protein {ECO:0000313|EMBL:CAG33441.1};"]
[9779,"'TBC1D5'",462,336,465,421,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0030904///retromer complex+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:1905394///retromer complex binding","GO:0006886///intracellular protein transport+++GO:0016236///macroautophagy+++GO:1902017///regulation of cilium assembly+++GO:0002092///positive regulation of receptor internalization+++GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0006914///autophagy+++GO:0090630///activation of GTPase activity+++GO:0042594///response to starvation","TBC1 domain family member 5","[TBCD5_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 5;+++[A0A024R2H0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_a {ECO:0000313|EMBL:EAW64287.1};+++[A0A024R2J9_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_b {ECO:0000313|EMBL:EAW64288.1};+++[B9A6K1_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5 {ECO:0000313|EMBL:BAH16629.1};+++[C9J397_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000410596}; Flags: Fragment;+++[C9J3F6_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411925};+++[C9JDR8_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396239}; Flags: Fragment;+++[C9JED7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000415379}; Flags: Fragment;+++[C9JIU4_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396850}; Flags: Fragment;+++[C9JMP7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000408603}; Flags: Fragment;+++[C9JNM0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000414159}; Flags: Fragment;+++[C9JW04_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000387395}; Flags: Fragment;+++[C9JWX0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000399967}; Flags: Fragment;+++[C9K0P2_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000393882}; Flags: Fragment;+++[F2Z3C3_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000424998}; Flags: Fragment;+++[F2Z3I5_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411780};"]
[978,"'CDA'",4,3,4,3.66666666666667,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00983///Drug metabolism - other enzymes",null,null,"R08221///5'-deoxy-5-fluorocytidine aminohydrolase   5'-Deoxy-5-fluorocytidine + H2O <=> 5'-Deoxy-5-fluorouridine + Ammonia+++R02485///deoxycytidine aminohydrolase   Deoxycytidine + H2O <=> Deoxyuridine + Ammonia+++R01878///Cytidine aminohydrolase   Cytidine + H2O <=> Uridine + Ammonia","GO:1904813///ficolin-1-rich granule lumen+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:1904724///tertiary granule lumen","GO:0008270///zinc ion binding+++GO:0004126///cytidine deaminase activity+++GO:0042803///protein homodimerization activity+++GO:0003824///catalytic activity+++GO:0001882///nucleoside binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity","GO:0043097///pyrimidine nucleoside salvage+++GO:0030308///negative regulation of cell growth+++GO:0045980///negative regulation of nucleotide metabolic process+++GO:0008655///pyrimidine-containing compound salvage+++GO:0043312///neutrophil degranulation+++GO:0019858///cytosine metabolic process+++GO:0009972///cytidine deamination+++GO:0051289///protein homotetramerization+++GO:0007166///cell surface receptor signaling pathway","cytidine deaminase","[CDD_HUMAN|Reviewed]RecName: Full=Cytidine deaminase; EC=3.5.4.5; AltName: Full=Cytidine aminohydrolase;+++[Q71UE9_HUMAN|Unreviewed]SubName: Full=Cytidine deaminase {ECO:0000313|EMBL:AAC69599.1}; EC=3.5.4.5 {ECO:0000313|EMBL:AAC69599.1}; Flags: Fragment;"]
[9780,"'PIEZO1'",7742,7230,7805,7592.33333333333,null,"H01978///Dehydrated hereditary stomatocytosis+++H02001///Familial pseudohyperkalemia+++H00811///Distal arthrogryposis (DA)+++H00232///Hereditary stomatocytosis (HSt)",null,null,"GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0031258///lamellipodium membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane","GO:0008381///mechanosensitive ion channel activity+++GO:0005261///cation channel activity","GO:0033625///positive regulation of integrin activation+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0042391///regulation of membrane potential+++GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0050982///detection of mechanical stimulus+++GO:0006812///cation transport+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071260///cellular response to mechanical stimulus","piezo type mechanosensitive ion channel component 1","[PIEZ1_HUMAN|Reviewed]RecName: Full=Piezo-type mechanosensitive ion channel component 1; AltName: Full=Membrane protein induced by beta-amyloid treatment; Short=Mib; AltName: Full=Protein FAM38A;+++[E7EUT2_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000333704};+++[H0YB49_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000428673}; Flags: Fragment;+++[H3BRR7_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456373}; Flags: Fragment;+++[H3BSF6_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456680}; Flags: Fragment;+++[H7C2J5_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000406358}; Flags: Fragment;+++[M4QHP2_HUMAN|Unreviewed]RecName: Full=Piezo-type mechanosensitive ion channel component {ECO:0000256|RuleBase:RU362023};+++[Q96HU3_HUMAN|Unreviewed]SubName: Full=FAM38A protein {ECO:0000313|EMBL:AAH08073.2};"]
[9781,"'RNF144A'",72,76.98,89,79.3266666666667,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0010008///endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding","GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination","ring finger protein 144A","[R144A_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF144A; EC=2.3.2.31 {ECO:0000250|UniProtKB:O60260}; AltName: Full=RING finger protein 144A; AltName: Full=UbcM4-interacting protein 4; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 4;+++[C9JLH4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF144A {ECO:0000313|Ensembl:ENSP00000414420}; Flags: Fragment;+++[H7C3G0_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;"]
[9782,"'MATR3'",3129,2207,2546,2627.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0003676///nucleic acid binding+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0035198///miRNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0002218///activation of innate immune response+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0045087///innate immune response+++GO:0002376///immune system process","matrin 3","[MATR3_HUMAN|Reviewed]RecName: Full=Matrin-3;+++[A0A0R4J2E8_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000354346};+++[A0A1B0GX04_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421145}; Flags: Fragment;+++[A8MXP9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000378279};+++[B3KM87_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10526 fis, clone NT2RP2000931, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG50899.1};+++[B4DF66_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55637, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG57327.1};+++[D6R8Z5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422233}; Flags: Fragment;+++[D6R991_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423290}; Flags: Fragment;+++[D6R9F3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422137}; Flags: Fragment;+++[D6R9N0_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423521}; Flags: Fragment;+++[D6RAM9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421666}; Flags: Fragment;+++[D6RAY2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424646}; Flags: Fragment;+++[D6RB45_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424431}; Flags: Fragment;+++[D6RBI2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422700}; Flags: Fragment;+++[D6RBK5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422649}; Flags: Fragment;+++[D6RBS2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422590}; Flags: Fragment;+++[D6RCM3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427168};+++[D6RE02_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000425150}; Flags: Fragment;+++[D6REK4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426801}; Flags: Fragment;+++[D6REM6_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426743};+++[D6RIA2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427557}; Flags: Fragment;+++[H0Y8T4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422054}; Flags: Fragment;+++[Q68E03_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000480093};+++[Q9H4N1_HUMAN|Unreviewed]SubName: Full=Clone CDABP0107 mRNA sequence {ECO:0000313|EMBL:AAG02007.1};"]
[9783,"'RIMS3'",103,83,93,93,{"$nulls":4},"GO:0030054///cell junction+++GO:0016020///membrane+++GO:0042734///presynaptic membrane+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0045202///synapse+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0048786///presynaptic active zone","GO:0017137///Rab GTPase binding+++GO:0044325///ion channel binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0017156///calcium ion regulated exocytosis+++GO:0042391///regulation of membrane potential+++GO:0050806///positive regulation of synaptic transmission+++GO:0048167///regulation of synaptic plasticity+++GO:0006887///exocytosis+++GO:0006836///neurotransmitter transport+++GO:2000300///regulation of synaptic vesicle exocytosis","regulating synaptic membrane exocytosis 3","[RIMS3_HUMAN|Reviewed]RecName: Full=Regulating synaptic membrane exocytosis protein 3; Short=Nim3; AltName: Full=RIM3 gamma; AltName: Full=Rab-3-interacting molecule 3; Short=RIM 3;+++[L8EAQ2_HUMAN|Unreviewed]SubName: Full=Alternative protein RIMS3 {ECO:0000313|EMBL:CCQ43458.1};+++[X5D2V8_HUMAN|Unreviewed]SubName: Full=Regulating synaptic membrane exocytosis 3 isoform C {ECO:0000313|EMBL:AHW56609.1}; Flags: Fragment;"]
[9784,"'SNX17'",1281,1430,1403,1371.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005769///early endosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005768///endosome+++GO:0005623///cell+++GO:0010008///endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0050750///low-density lipoprotein particle receptor binding+++GO:0008289///lipid binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0035091///phosphatidylinositol binding","GO:0006898///receptor-mediated endocytosis+++GO:0016197///endosomal transport+++GO:0003279///cardiac septum development+++GO:0006707///cholesterol catabolic process+++GO:0035904///aorta development+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0015031///protein transport+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0060976///coronary vasculature development+++GO:0006886///intracellular protein transport","sorting nexin 17","[SNX17_HUMAN|Reviewed]RecName: Full=Sorting nexin-17;+++[B4DDM3_HUMAN|Unreviewed]SubName: Full=Sorting nexin 17, isoform CRA_a {ECO:0000313|EMBL:EAX00584.1}; SubName: Full=cDNA FLJ51047, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60979.1}; SubName: Full=cDNA FLJ53821, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG56784.1}; SubName: Full=cDNA FLJ61770, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG58262.1};+++[B4DQ37_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56223, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60799.1};+++[B4DTB8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51699, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG61930.1};+++[F8WAZ0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000405399};+++[F8WEG6_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000401922};+++[F8WFA0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000399727};"]
[9785,"'DHX38'",600,588,505,564.333333333333,"03040///Spliceosome",{"$nulls":3},"GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005681///spliceosomal complex","GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0006405///RNA export from nucleus","DEAH-box helicase 38","[PRP16_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase DHX38; AltName: Full=DEAH box protein 38;+++[B4DM30_HUMAN|Unreviewed]SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 38, isoform CRA_d {ECO:0000313|EMBL:EAW59183.1}; SubName: Full=cDNA FLJ50987, highly similar to Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|EMBL:BAG59742.1};+++[H3BMS7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000454521}; Flags: Fragment;+++[H3BQT9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000455939}; Flags: Fragment;+++[H3BV01_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000457887}; Flags: Fragment;+++[J3KRT1_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462149};+++[J3KSA8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462397}; Flags: Fragment;+++[J3KTG2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462965}; Flags: Fragment;"]
[9786,"'KIAA0586'",243,166,200,203,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04140///Autophagy - animal+++04137///Mitophagy - animal","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0036064///ciliary basal body+++GO:0001917///photoreceptor inner segment+++GO:0042995///cell projection+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0019904///protein domain specific binding+++GO:0043021///ribonucleoprotein complex binding+++GO:1990247///N6-methyladenosine-containing RNA binding+++GO:0004857///enzyme inhibitor activity+++GO:1990827///deaminase binding+++GO:0003729///mRNA binding","GO:0070201///regulation of establishment of protein localization+++GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly","KIAA0586","[TALD3_HUMAN|Reviewed]RecName: Full=Protein TALPID3;+++[A0A087WYM5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000481936};+++[B4DYW5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61484 {ECO:0000313|EMBL:BAG63877.1};+++[B7Z7W7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52366 {ECO:0000313|EMBL:BAH13753.1};+++[G3V2T5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000450855}; Flags: Fragment;+++[G3V4J0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451831}; Flags: Fragment;+++[G3V5U9_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000452536};+++[H0YJF0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451356}; Flags: Fragment;+++[L0R885_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0586 {ECO:0000313|EMBL:CCO13756.1};"]
[9787,"'DLGAP5'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005819///spindle+++GO:0031616///spindle pole centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0023052///signaling+++GO:0006470///protein dephosphorylation+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0008283///cell proliferation+++GO:0007221///positive regulation of transcription of Notch receptor target","DLG associated protein 5","[DLGP5_HUMAN|Reviewed]RecName: Full=Disks large-associated protein 5; Short=DAP-5; AltName: Full=Discs large homolog 7; AltName: Full=Disks large-associated protein DLG7; AltName: Full=Hepatoma up-regulated protein; Short=HURP;+++[G3V4E5_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000451747}; Flags: Fragment;+++[G3V543_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000452168};"]
[9788,"'MTSS1'",377.94,271,594,414.313333333333,"00190///Oxidative phosphorylation+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease+++01100///Metabolic pathways+++05016///Huntington's disease+++05010///Alzheimer's disease+++04714///Thermogenesis+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04723///Retrograde endocannabinoid signaling","H00473///Mitochondrial complex I deficiency","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0030139///endocytic vesicle","GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding","GO:0072160///nephron tubule epithelial cell differentiation+++GO:0072102///glomerulus morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007009///plasma membrane organization+++GO:0071498///cellular response to fluid shear stress+++GO:0030035///microspike assembly+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis+++GO:0061333///renal tubule morphogenesis","MTSS1, I-BAR domain containing","[MTSS1_HUMAN|Reviewed]RecName: Full=Metastasis suppressor protein 1; AltName: Full=Metastasis suppressor YGL-1; AltName: Full=Missing in metastasis protein;+++[A5YM41_HUMAN|Unreviewed]SubName: Full=MTSS1 protein {ECO:0000313|EMBL:ABQ59025.1};+++[E5RJX3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428145}; Flags: Fragment;+++[E7EWW5_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428319};+++[H0YAZ8_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428348}; Flags: Fragment;+++[H0YB53_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428685}; Flags: Fragment;+++[H0YBL3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000429752}; Flags: Fragment;"]
[9789,"'SPCS2'",602,612,610,608,"03060///Protein export",null,null,"R04018///Acylneuraminyl hydrolase Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O","GO:0005787///signal peptidase complex+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0031090///organelle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005783///endoplasmic reticulum","GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0045047///protein targeting to ER","signal peptidase complex subunit 2","[SPCS2_HUMAN|Reviewed]RecName: Full=Signal peptidase complex subunit 2; EC=3.4.-.-; AltName: Full=Microsomal signal peptidase 25 kDa subunit; Short=SPase 25 kDa subunit;+++[A0A087WUC6_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000478550};+++[E9PI68_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000436759};+++[E9PL01_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000433439};+++[E9PRB9_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434248};+++[H0YE04_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434706}; Flags: Fragment;"]
[9790,"'BMS1'",726.65,662.48,690.55,693.226666666667,"03008///Ribosome biogenesis in eukaryotes","H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0030686///90S preribosome+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0034511///U3 snoRNA binding+++GO:0000166///nucleotide binding","GO:0042254///ribosome biogenesis+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","BMS1, ribosome biogenesis factor","[BMS1_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;"]
[9791,"'PTDSS1'",991,863,902,918.666666666667,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways","H01832///Lenz-Majewski syndrome",null,"R07377///Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006659///phosphatidylserine biosynthetic process","phosphatidylserine synthase 1","[PTSS1_HUMAN|Reviewed]RecName: Full=Phosphatidylserine synthase 1; Short=PSS-1; Short=PtdSer synthase 1; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme I;+++[J3KNR6_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 1, isoform CRA_a {ECO:0000313|EMBL:EAW91753.1};+++[Q9BSY0_HUMAN|Unreviewed]SubName: Full=PTDSS1 protein {ECO:0000313|EMBL:AAH04502.2}; Flags: Fragment;"]
[9792,"'SERTAD2'",632,453,547,544,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003713///transcription coactivator activity","GO:0030308///negative regulation of cell growth+++GO:0045893///positive regulation of transcription, DNA-templated","SERTA domain containing 2","[SRTD2_HUMAN|Reviewed]RecName: Full=SERTA domain-containing protein 2; AltName: Full=Transcriptional regulator interacting with the PHD-bromodomain 2; Short=TRIP-Br2;"]
[9793,"'CKAP5'",1423,1181,1304,1302.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000776///kinetochore+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0000930///gamma-tubulin complex+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore+++GO:0005813///centrosome+++GO:0000922///spindle pole+++GO:0005886///plasma membrane+++GO:0005694///chromosome+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0032991///protein-containing complex+++GO:0005730///nucleolus+++GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end","GO:0051010///microtubule plus-end binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007098///centrosome cycle+++GO:0007019///microtubule depolymerization+++GO:0051301///cell division+++GO:0051298///centrosome duplication+++GO:0050658///RNA transport+++GO:0007051///spindle organization+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0046785///microtubule polymerization+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007049///cell cycle","cytoskeleton associated protein 5","[CKAP5_HUMAN|Reviewed]RecName: Full=Cytoskeleton-associated protein 5; AltName: Full=Colonic and hepatic tumor overexpressed gene protein; Short=Ch-TOG;+++[E9PQH5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436769}; Flags: Fragment;+++[H0YCF6_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000431509}; Flags: Fragment;+++[H0YDX5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000434523}; Flags: Fragment;+++[H0YEK7_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436052}; Flags: Fragment;+++[Q8IYN5_HUMAN|Unreviewed]SubName: Full=CKAP5 protein {ECO:0000313|EMBL:AAH35554.1};"]
[9794,"'MAML1'",1014,776,853,881,"04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05165///Human papillomavirus infection","H01508///Salivary gland cancer",null,null,"GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042605///peptide antigen binding+++GO:0019901///protein kinase binding","GO:0045445///myoblast differentiation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0010831///positive regulation of myotube differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0003162///atrioventricular node development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0060928///atrioventricular node cell development","mastermind like transcriptional coactivator 1","[MAML1_HUMAN|Reviewed]RecName: Full=Mastermind-like protein 1; Short=Mam-1;"]
[9796,"'PHYHIP'",237,274,188,233,"04623///Cytosolic DNA-sensing pathway+++01100///Metabolic pathways+++04137///Mitophagy - animal+++05169///Epstein-Barr virus infection+++00230///Purine metabolism+++00240///Pyrimidine metabolism+++04140///Autophagy - animal+++03020///RNA polymerase",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA ATP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA CTP + RNA <=> Diphosphate + RNA","GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0016607///nuclear speck","GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0045089///positive regulation of innate immune response","phytanoyl-CoA 2-hydroxylase interacting protein","[PHYIP_HUMAN|Reviewed]RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein; AltName: Full=Phytanoyl-CoA hydroxylase-associated protein 1; Short=PAHX-AP1; Short=PAHXAP1;+++[E5RHN5_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA hydroxylase-interacting protein {ECO:0000313|Ensembl:ENSP00000430870}; Flags: Fragment;"]
[9797,"'TATDN2'",601,500,652,584.333333333333,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0004518///nuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters","GO:0006259///DNA metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0036498///IRE1-mediated unfolded protein response","TatD DNase domain containing 2","[TATD2_HUMAN|Reviewed]RecName: Full=Putative deoxyribonuclease TATDN2; EC=3.1.21.-;+++[A0A024R2F3_HUMAN|Unreviewed]SubName: Full=TatD DNase domain containing 2, isoform CRA_a {ECO:0000313|EMBL:EAW64071.1};+++[H7BZJ2_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN2 {ECO:0000313|Ensembl:ENSP00000389896}; Flags: Fragment;"]
[9798,"'IST1'",969,970,900,946.333333333333,"04144///Endocytosis",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005737///cytoplasm+++GO:0005635///nuclear envelope+++GO:0005856///cytoskeleton+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0035578///azurophil granule lumen","GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding+++GO:0090541///MIT domain binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061640///cytoskeleton-dependent cytokinesis+++GO:0043312///neutrophil degranulation+++GO:0036258///multivesicular body assembly+++GO:1904903///ESCRT III complex disassembly+++GO:0048672///positive regulation of collateral sprouting+++GO:0051301///cell division+++GO:0019076///viral release from host cell+++GO:0045184///establishment of protein localization+++GO:0009838///abscission+++GO:0008104///protein localization+++GO:0046745///viral capsid secondary envelopment+++GO:0045862///positive regulation of proteolysis+++GO:0015031///protein transport+++GO:0007049///cell cycle","IST1, ESCRT-III associated factor","[IST1_HUMAN|Reviewed]RecName: Full=IST1 homolog; Short=hIST1; AltName: Full=Putative MAPK-activating protein PM28;+++[B4DXC9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59095 {ECO:0000313|EMBL:BAG63341.1};+++[E9PF00_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000410081};+++[F5GXM3_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000398505}; Flags: Fragment;+++[H3BMU1_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000454541}; Flags: Fragment;+++[H3BPP6_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455409}; Flags: Fragment;+++[H3BQ38_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455590}; Flags: Fragment;+++[H3BQF7_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455757}; Flags: Fragment;+++[H3BRE2_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000456200}; Flags: Fragment;+++[H3BUI0_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000457646}; Flags: Fragment;+++[J3KR23_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000414942}; Flags: Fragment;+++[J3QQP8_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000463833};"]
[98,"'ACYP2'",140,172,177,163,"00627///Aminobenzoate degradation+++01120///Microbial metabolism in diverse environments+++00620///Pyruvate metabolism",null,null,"R00317///Acetyl phosphate phosphohydrolase   Acetyl phosphate + H2O <=> Acetate + Orthophosphate+++R01515///3-Phospho-D-glyceroyl phosphate phosphohydrolase   3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate+++R01421///Benzoyl phosphate phosphohydrolase   Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate","GO:0005623///cell+++GO:1990111///spermatoproteasome complex+++GO:0017053///transcriptional repressor complex+++GO:0035868///alphav-beta3 integrin-HMGB1 complex+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005839///proteasome core complex+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000793///condensed chromosome+++GO:0070062///extracellular exosome","GO:0042802///identical protein binding+++GO:0003998///acylphosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0006796///phosphate-containing compound metabolic process","acylphosphatase 2","[ACYP2_HUMAN|Reviewed]RecName: Full=Acylphosphatase-2; EC=3.6.1.7; AltName: Full=Acylphosphatase, muscle type isozyme; AltName: Full=Acylphosphate phosphohydrolase 2;+++[A0A140VJD7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[D6W5B6_HUMAN|Unreviewed]SubName: Full=Acylphosphatase 2, muscle type, isoform CRA_a {ECO:0000313|EMBL:EAX00155.1};+++[E9PF46_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[F8WA34_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[Q4ZFV7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ACYP2 {ECO:0000313|EMBL:AAX88874.1}; Flags: Fragment;+++[Q53TK7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX1_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX8_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475333};+++[U3KQ09_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475424};+++[U3KQ94_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475658}; SubName: Full=HCG2040114, isoform CRA_a {ECO:0000313|EMBL:EAX00159.1};+++[U3KQL2_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520};"]
[9801,"'MRPL19'",306,244,256,268.666666666667,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0015934///large ribosomal subunit+++GO:0005840///ribosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0031965///nuclear membrane","GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006412///translation+++GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:1990830///cellular response to leukemia inhibitory factor","mitochondrial ribosomal protein L19","[RM19_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L19, mitochondrial; Short=L19mt; Short=MRP-L19; AltName: Full=39S ribosomal protein L15, mitochondrial; Short=L15mt; Short=MRP-L15; AltName: Full=Mitochondrial large ribosomal subunit protein bL19m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[A0A0A0MRF4_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000351639};+++[H7C2J0_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000406267}; Flags: Fragment;+++[S4R3W9_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000474821}; Flags: Fragment;+++[S4R455_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000475090}; Flags: Fragment;"]
[9802,"'DAZAP2'",2505,2458,2690,2551,{"$nulls":4},"GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0030971///receptor tyrosine kinase binding+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding","GO:0071902///positive regulation of protein serine/threonine kinase activity","DAZ associated protein 2","[DAZP2_HUMAN|Reviewed]RecName: Full=DAZ-associated protein 2; AltName: Full=Deleted in azoospermia-associated protein 2;+++[A0A024R110_HUMAN|Unreviewed]SubName: Full=DAZ associated protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW58182.1};+++[E9PE89_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000404968};+++[F8VUW5_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000447842};+++[S4R3Q0_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000474597};"]
[9804,"'TOMM20'",1761,1483,1713,1652.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005740///mitochondrial envelope+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0005741///mitochondrial outer membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0030943///mitochondrion targeting sequence binding+++GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051082///unfolded protein binding","GO:0016031///tRNA import into mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006626///protein targeting to mitochondrion+++GO:0006886///intracellular protein transport+++GO:0014850///response to muscle activity+++GO:0016579///protein deubiquitination+++GO:1905242///response to 3,3',5-triiodo-L-thyronine+++GO:0006605///protein targeting+++GO:0015031///protein transport+++GO:0070096///mitochondrial outer membrane translocase complex assembly","translocase of outer mitochondrial membrane 20","[TOM20_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM20 homolog; AltName: Full=Mitochondrial 20 kDa outer membrane protein; AltName: Full=Outer mitochondrial membrane receptor Tom20;+++[A0A024R3W2_HUMAN|Unreviewed]SubName: Full=Translocase of outer mitochondrial membrane 20 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW70004.1};"]
[9805,"'SCRN1'",2574,2071,2197,2280.66666666667,{"$nulls":4},"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016805///dipeptidase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0006887///exocytosis+++GO:0006508///proteolysis","secernin 1","[SCRN1_HUMAN|Reviewed]RecName: Full=Secernin-1;+++[A0A024RA21_HUMAN|Unreviewed]SubName: Full=Secernin 1, isoform CRA_a {ECO:0000313|EMBL:EAW93927.1};+++[A0A090N7T9_HUMAN|Unreviewed]SubName: Full=Secernin 1 {ECO:0000313|EMBL:EAL24458.1};+++[B8ZZP4_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000387052};+++[C9J7U9_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000406289}; Flags: Fragment;+++[C9K052_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000413184}; Flags: Fragment;"]
[9806,"'SPOCK2'",39,49,49,45.6666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix","GO:0005509///calcium ion binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0050840///extracellular matrix binding+++GO:0005539///glycosaminoglycan binding+++GO:0005518///collagen binding","GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0010951///negative regulation of endopeptidase activity+++GO:2000147///positive regulation of cell motility+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0007416///synapse assembly+++GO:0045595///regulation of cell differentiation+++GO:0030198///extracellular matrix organization","SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2","[TICN2_HUMAN|Reviewed]RecName: Full=Testican-2; AltName: Full=SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2; Flags: Precursor;+++[A0A024QZQ5_HUMAN|Unreviewed]SubName: Full=Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (Testican) 2, isoform CRA_b {ECO:0000313|EMBL:EAW54443.1};+++[F5H283_HUMAN|Unreviewed]SubName: Full=Testican-2 {ECO:0000313|Ensembl:ENSP00000439445};+++[L8E8K3_HUMAN|Unreviewed]SubName: Full=Alternative protein SPOCK2 {ECO:0000313|EMBL:CCQ43459.1};"]
[9807,"'IP6K1'",987,832,879,899.333333333333,"04138///Autophagy - yeast+++04070///Phosphatidylinositol signaling system",null,null,"R10548///ATP:1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 5-phosphotransferase   ATP + 1-Diphosinositol pentakisphosphate <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate+++R09087///ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase   ATP + Phytic acid <=> ADP + 5-PP-InsP5","GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0052839///inositol diphosphate tetrakisphosphate kinase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0000829///inositol heptakisphosphate kinase activity+++GO:0016301///kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity+++GO:0005524///ATP binding+++GO:0052836///inositol 5-diphosphate pentakisphosphate 5-kinase activity","GO:0043647///inositol phosphate metabolic process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0016310///phosphorylation","inositol hexakisphosphate kinase 1","[IP6K1_HUMAN|Reviewed]RecName: Full=Inositol hexakisphosphate kinase 1; Short=InsP6 kinase 1; EC=2.7.4.21; AltName: Full=Inositol hexaphosphate kinase 1;+++[A0A024R2X2_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[C9JNA8_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[L8EAR7_HUMAN|Unreviewed]SubName: Full=Alternative protein IP6K1 {ECO:0000313|EMBL:CCQ43876.1};"]
[9810,"'RNF40'",2460,2386,2465,2437,{"$nulls":4},"GO:0033503///HULC complex+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0005634///nucleus+++GO:0000151///ubiquitin ligase complex+++GO:0043679///axon terminus+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0017075///syntaxin-1 binding+++GO:0042803///protein homodimerization activity","GO:0043434///response to peptide hormone+++GO:0016567///protein ubiquitination+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0007346///regulation of mitotic cell cycle+++GO:0006325///chromatin organization+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0033523///histone H2B ubiquitination+++GO:0010390///histone monoubiquitination","ring finger protein 40","[BRE1B_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase BRE1B; Short=BRE1-B; EC=2.3.2.27 {ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:19410543}; AltName: Full=95 kDa retinoblastoma-associated protein; Short=RBP95; AltName: Full=RING finger protein 40; AltName: Full=RING-type E3 ubiquitin transferase BRE1B {ECO:0000305};+++[A0A087WTK2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A0A0S2Z4Z2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[A0A0S2Z537_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A8K6K1_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BP71_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BQ99_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BS50_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BUL6_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[I3L332_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[R4GN66_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase BRE1B {ECO:0000313|Ensembl:ENSP00000473507}; Flags: Fragment;"]
[9811,"'CTIF'",1418,1329,1373,1373.33333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0008494///translation activator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045727///positive regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006417///regulation of translation","cap binding complex dependent translation initiation factor","[CTIF_HUMAN|Reviewed]RecName: Full=CBP80/20-dependent translation initiation factor;+++[A0A024R259_HUMAN|Unreviewed]SubName: Full=KIAA0427, isoform CRA_a {ECO:0000313|EMBL:EAW62927.1};+++[K7EK08_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000465405}; Flags: Fragment;+++[K7EPK6_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467425}; Flags: Fragment;+++[K7EQS5_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467957}; Flags: Fragment;+++[K7EQS9_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467965}; Flags: Fragment;"]
[9812,"'DELE1'",1067,961,1143,1057,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00606///Early infantile epileptic encephalopathy+++H01775///PCDH19-related epilepsy syndrome",null,null,"GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process","DAP3 binding cell death enhancer 1","[DELE1_HUMAN|Reviewed]RecName: Full=DAP3-binding cell death enhancer 1 {ECO:0000312|HGNC:HGNC:28969}; AltName: Full=Death ligand signal enhancer {ECO:0000303|PubMed:20563667}; Flags: Precursor;+++[D6RBI8_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000422686}; Flags: Fragment;+++[H0YA48_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000426138}; Flags: Fragment;"]
[9813,"'EFCAB14'",1806,1251,1570,1542.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding",null,"EF-hand calcium binding domain 14","[EFC14_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 14;+++[S4R3Q1_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000474599}; Flags: Fragment;"]
[9814,"'SFI1'",146.94,137.87,129.14,137.983333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005814///centriole","GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0005515///protein binding+++GO:0004609///phosphatidylserine decarboxylase activity+++GO:0019902///phosphatase binding","GO:0006629///lipid metabolic process+++GO:0010923///negative regulation of phosphatase activity+++GO:0016540///protein autoprocessing+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0008654///phospholipid biosynthetic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0000086///G2/M transition of mitotic cell cycle","SFI1 centrin binding protein","[SFI1_HUMAN|Reviewed]RecName: Full=Protein SFI1 homolog; Short=hSFI1;+++[A0A024R1K2_HUMAN|Unreviewed]SubName: Full=Sfi1 homolog, spindle assembly associated (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW59983.1};+++[D3YTJ2_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000401199};+++[E5RJU6_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000430488};+++[H0Y5I7_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000398871}; Flags: Fragment;+++[H0Y836_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000416931}; Flags: Fragment;+++[H7BZF3_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000389364}; Flags: Fragment;+++[H7C2F1_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000405541}; Flags: Fragment;+++[X6RJF9_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000411793}; Flags: Fragment;"]
[9815,"'GIT2'",1138,1005,1047,1063.33333333333,"04144///Endocytosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation","GIT ArfGAP 2","[GIT2_HUMAN|Reviewed]RecName: Full=ARF GTPase-activating protein GIT2; Short=ARF GAP GIT2; AltName: Full=Cool-interacting tyrosine-phosphorylated protein 2; Short=CAT-2; Short=CAT2; AltName: Full=G protein-coupled receptor kinase-interactor 2; AltName: Full=GRK-interacting protein 2;+++[A0A024RBI8_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase interactor 2, isoform CRA_a {ECO:0000313|EMBL:EAW97886.1};+++[B5BU58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70108.1};+++[F8VXI9_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000448832};+++[F8W822_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000323833};+++[F8WAK2_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000346585};+++[Q68DM7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G01261 {ECO:0000313|EMBL:CAH18193.1}; Flags: Fragment;+++[Q6FI58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70242.1}; SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 variant {ECO:0000313|EMBL:BAD96456.1}; SubName: Full=GIT2 protein {ECO:0000313|EMBL:CAG38599.1};+++[R4GNG3_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000473637}; Flags: Fragment;"]
[9816,"'URB2'",142,121,128,130.333333333333,{"$nulls":4},"GO:0030496///midbody+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016235///aggresome",null,"GO:0042254///ribosome biogenesis","URB2 ribosome biogenesis homolog","[URB2_HUMAN|Reviewed]RecName: Full=Unhealthy ribosome biogenesis protein 2 homolog;+++[Q5VYD0_HUMAN|Unreviewed]SubName: Full=Unhealthy ribosome biogenesis protein 2 homolog {ECO:0000313|Ensembl:ENSP00000395107}; Flags: Fragment;+++[Q6PCC8_HUMAN|Unreviewed]SubName: Full=URB2 protein {ECO:0000313|EMBL:AAH59381.1}; Flags: Fragment;"]
[9817,"'KEAP1'",1079,1057,1068,1068,"05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04120///Ubiquitin mediated proteolysis+++05225///Hepatocellular carcinoma","H00048///Hepatocellular carcinoma",null,null,"GO:0005884///actin filament+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0030496///midbody+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0042802///identical protein binding+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043687///post-translational protein modification+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0071353///cellular response to interleukin-4+++GO:0016032///viral process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0016567///protein ubiquitination+++GO:0045604///regulation of epidermal cell differentiation","kelch like ECH associated protein 1","[KEAP1_HUMAN|Reviewed]RecName: Full=Kelch-like ECH-associated protein 1; AltName: Full=Cytosolic inhibitor of Nrf2; Short=INrf2; AltName: Full=Kelch-like protein 19;+++[A0A024R7C0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW84112.1};+++[K7EJ49_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465024}; Flags: Fragment;+++[K7EJD8_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465126}; Flags: Fragment;+++[K7EMY1_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000466704}; Flags: Fragment;+++[K7EPZ3_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000467601}; Flags: Fragment;+++[K7EQX2_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468014}; Flags: Fragment;+++[K7ESE0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468671}; Flags: Fragment;"]
[9818,"'NUP58'",460,319,325,368,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005643///nuclear pore+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0015031///protein transport+++GO:0006913///nucleocytoplasmic transport+++GO:0006406///mRNA export from nucleus+++GO:0016032///viral process+++GO:0051260///protein homooligomerization+++GO:0051028///mRNA transport+++GO:0042306///regulation of protein import into nucleus+++GO:0051290///protein heterotetramerization+++GO:0051291///protein heterooligomerization+++GO:0070208///protein heterotrimerization","nucleoporin 58","[NUP58_HUMAN|Reviewed]RecName: Full=Nucleoporin p58/p45 {ECO:0000305}; AltName: Full=58 kDa nucleoporin {ECO:0000312|HGNC:HGNC:20261}; AltName: Full=Nucleoporin-like protein 1;+++[F8WBZ1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418244};+++[F8WC35_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418904};+++[F8WCJ8_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418341};+++[H7BYF2_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000371166}; Flags: Fragment;+++[Q5JRG1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000408147}; Flags: Fragment;"]
[9819,"'TSC22D2'",661,557,458,558.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006970///response to osmotic stress","TSC22 domain family member 2","[T22D2_HUMAN|Reviewed]RecName: Full=TSC22 domain family protein 2; AltName: Full=TSC22-related-inducible leucine zipper protein 4;+++[B4DN36_HUMAN|Unreviewed]SubName: Full=TSC22 domain family, member 2, isoform CRA_d {ECO:0000313|EMBL:EAW78841.1}; SubName: Full=cDNA FLJ51900, highly similar to TSC22 domain family protein 2 {ECO:0000313|EMBL:BAG60098.1};+++[H0Y865_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000417747}; Flags: Fragment;+++[H0Y8E9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000420689}; Flags: Fragment;+++[H7C4U3_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000418149}; Flags: Fragment;"]
[9820,"'CUL7'",1350,1235,1398,1327.66666666667,"04120///Ubiquitin mediated proteolysis","H00509///3M syndrome",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005680///anaphase-promoting complex+++GO:1990393///3M complex+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0007030///Golgi organization+++GO:0006508///proteolysis+++GO:0001890///placenta development+++GO:0000226///microtubule cytoskeleton organization+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001570///vasculogenesis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0007088///regulation of mitotic nuclear division+++GO:0001837///epithelial to mesenchymal transition+++GO:0000281///mitotic cytokinesis+++GO:0016567///protein ubiquitination+++GO:0016032///viral process","cullin 7","[CUL7_HUMAN|Reviewed]RecName: Full=Cullin-7; Short=CUL-7;+++[L8E835_HUMAN|Unreviewed]SubName: Full=Alternative protein CUL7 {ECO:0000313|EMBL:CCQ43460.1};"]
[9821,"'RB1CC1'",979,648,737,788,"04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0034045///phagophore assembly site membrane+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000407///phagophore assembly site+++GO:0005789///endoplasmic reticulum membrane+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0019898///extrinsic component of membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0007507///heart development+++GO:0043066///negative regulation of apoptotic process+++GO:0000045///autophagosome assembly+++GO:0030242///autophagy of peroxisome+++GO:0001934///positive regulation of protein phosphorylation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0001889///liver development+++GO:0000422///autophagy of mitochondrion+++GO:0016241///regulation of macroautophagy+++GO:0061709///reticulophagy+++GO:0006914///autophagy+++GO:0007049///cell cycle+++GO:0061723///glycophagy+++GO:0016236///macroautophagy+++GO:0045793///positive regulation of cell size+++GO:0046330///positive regulation of JNK cascade","RB1 inducible coiled-coil 1","[RBCC1_HUMAN|Reviewed]RecName: Full=RB1-inducible coiled-coil protein 1; AltName: Full=FAK family kinase-interacting protein of 200 kDa; Short=FIP200;+++[E5RH44_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429918}; Flags: Fragment;+++[E5RH63_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429879}; Flags: Fragment;+++[E5RHX0_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429611}; Flags: Fragment;+++[E5RJC1_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429115};+++[H0YC28_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430792}; Flags: Fragment;+++[H0YC30_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430809}; Flags: Fragment;"]
[9823,"'ARMCX2'",726,750,719,731.666666666667,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane",null,"GO:0034613///cellular protein localization+++GO:0045944///positive regulation of transcription by RNA polymerase II","armadillo repeat containing X-linked 2","[ARMX2_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 2; AltName: Full=ARM protein lost in epithelial cancers on chromosome X 2; Short=Protein ALEX2;+++[A0A024RCG7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2, isoform CRA_a {ECO:0000313|EMBL:EAX02889.1};+++[A0A0B4J1X4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000393778}; Flags: Fragment;+++[A0A1B0GXK8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000415490}; Flags: Fragment;+++[A8K5M7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76303, highly similar to Homo sapiens armadillo repeat containing, X-linked 2 (ARMCX2), mRNA {ECO:0000313|EMBL:BAF84031.1};+++[Q5H9D7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42024.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000405376}; Flags: Fragment;+++[Q5H9D8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42023.1}; Flags: Fragment;+++[Q5H9E0_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42021.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000410151}; Flags: Fragment;+++[Q5H9E1_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42020.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000412481}; Flags: Fragment;"]
[9824,"'ARHGAP11A'",40,39,45,41.3333333333333,{"$nulls":4},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction","Rho GTPase activating protein 11A","[RHGBA_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 11A; AltName: Full=Rho-type GTPase-activating protein 11A;+++[A0A2X0SFK9_HUMAN|Unreviewed]SubName: Full=ARHGAP11A {ECO:0000313|EMBL:SPT35684.1}; Flags: Fragment;+++[H3BQ41_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000455593}; Flags: Fragment;+++[H3BR51_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000456078};"]
[9825,"'SPATA2'",392,383,355,376.666666666667,"04217///Necroptosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007283///spermatogenesis+++GO:0012501///programmed cell death+++GO:0007275///multicellular organism development+++GO:0050727///regulation of inflammatory response+++GO:0060544///regulation of necroptotic process+++GO:1990108///protein linear deubiquitination+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0070536///protein K63-linked deubiquitination","spermatogenesis associated 2","[SPAT2_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 2 {ECO:0000303|PubMed:27307491, ECO:0000303|PubMed:27458237};+++[A8K0S9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78311, highly similar to Homo sapiens spermatogenesis associated 2 (SPATA2), mRNA {ECO:0000313|EMBL:BAF82333.1};+++[B4DID4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50158, highly similar to Spermatogenesis-associated protein 2 {ECO:0000313|EMBL:BAG58446.1};+++[L8E7J6_HUMAN|Unreviewed]SubName: Full=Alternative protein SPATA2 {ECO:0000313|EMBL:CCQ43104.1};"]
[9826,"'ARHGEF11'",1004,1004,978,995.333333333333,"05200///Pathways in cancer+++04928///Parathyroid hormone synthesis, secretion and action+++04270///Vascular smooth muscle contraction+++05163///Human cytomegalovirus infection",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0030010///establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0006941///striated muscle contraction+++GO:0001558///regulation of cell growth+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","Rho guanine nucleotide exchange factor 11","[ARHGB_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 11; AltName: Full=PDZ-RhoGEF;+++[A0A2X0SFB0_HUMAN|Unreviewed]SubName: Full=ARHGEF11 {ECO:0000313|EMBL:SPT35722.1}; Flags: Fragment;"]
[9827,"'RGP1'",272,230,229,243.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0034066///RIC1-RGP1 guanyl-nucleotide exchange factor complex+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0032588///trans-Golgi network membrane+++GO:0000139///Golgi membrane+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0017137///Rab GTPase binding","GO:1903363///negative regulation of cellular protein catabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0042147///retrograde transport, endosome to Golgi","RGP1 homolog, RAB6A GEF complex partner 1","[RGP1_HUMAN|Reviewed]RecName: Full=RAB6A-GEF complex partner protein 2 {ECO:0000305}; AltName: Full=Retrograde Golgi transport protein RGP1 homolog {ECO:0000250|UniProtKB:P16664};+++[A8K0K1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76996 {ECO:0000313|EMBL:BAF82255.1};"]
[9828,"'ARHGEF17'",2415,2168,2379,2320.66666666667,{"$nulls":4},"GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","Rho guanine nucleotide exchange factor 17","[ARHGH_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 17; AltName: Full=164 kDa Rho-specific guanine-nucleotide exchange factor; Short=p164-RhoGEF; Short=p164RhoGEF; AltName: Full=Tumor endothelial marker 4;+++[A0A2R8Y4D7_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000493940};+++[A0A2X0TVV1_HUMAN|Unreviewed]SubName: Full=ARHGEF17 {ECO:0000313|EMBL:SPT35726.1}; Flags: Fragment;+++[H0YFZ8_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000441135}; Flags: Fragment;"]
[9829,"'DNAJC6'",177,107,117,133.666666666667,"04144///Endocytosis",{"$nulls":3},"GO:0045202///synapse+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0030276///clathrin binding+++GO:0017124///SH3 domain binding+++GO:0004725///protein tyrosine phosphatase activity","GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0061024///membrane organization+++GO:0006470///protein dephosphorylation+++GO:0072583///clathrin-dependent endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:0072318///clathrin coat disassembly+++GO:0035335///peptidyl-tyrosine dephosphorylation","DnaJ heat shock protein family (Hsp40) member C6","[AUXI_HUMAN|Reviewed]RecName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000305}; EC=3.1.3.48; AltName: Full=DnaJ homolog subfamily C member 6 {ECO:0000312|HGNC:HGNC:15469};+++[L0N9S0_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily C, member 6 {ECO:0000313|EMBL:CCE46052.1}; Flags: Fragment;+++[S4R305_HUMAN|Unreviewed]SubName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000313|Ensembl:ENSP00000473821}; Flags: Fragment;"]
[983,"'CDK1'",7,7,12,8.66666666666667,"05168///Herpes simplex infection+++05203///Viral carcinogenesis+++04114///Oocyte meiosis+++04540///Gap junction+++04110///Cell cycle+++05169///Epstein-Barr virus infection+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++04115///p53 signaling pathway",null,"M00693///Cell cycle - G2/M transition",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005813///centrosome+++GO:0070062///extracellular exosome+++GO:0005876///spindle microtubule+++GO:0030496///midbody+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005654///nucleoplasm+++GO:0097125///cyclin B1-CDK1 complex+++GO:0072686///mitotic spindle+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0035173///histone kinase activity+++GO:0005524///ATP binding+++GO:0030544///Hsp70 protein binding+++GO:0016740///transferase activity+++GO:0003682///chromatin binding+++GO:0001618///virus receptor activity+++GO:0000166///nucleotide binding+++GO:0097472///cyclin-dependent protein kinase activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0000187///activation of MAPK activity+++GO:0007344///pronuclear fusion+++GO:0014070///response to organic cyclic compound+++GO:0006468///protein phosphorylation+++GO:0030855///epithelial cell differentiation+++GO:0030261///chromosome condensation+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0014038///regulation of Schwann cell differentiation+++GO:0016572///histone phosphorylation+++GO:0046688///response to copper ion+++GO:0018105///peptidyl-serine phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0010628///positive regulation of gene expression+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0016477///cell migration+++GO:0006915///apoptotic process+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0065003///protein-containing complex assembly+++GO:0008283///cell proliferation+++GO:0045995///regulation of embryonic development+++GO:0044772///mitotic cell cycle phase transition+++GO:0016579///protein deubiquitination+++GO:0045471///response to ethanol+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0048678///response to axon injury+++GO:0031100///animal organ regeneration+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0014075///response to amine+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0045740///positive regulation of DNA replication+++GO:0007077///mitotic nuclear envelope disassembly+++GO:0007569///cell aging+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0006260///DNA replication+++GO:0007098///centrosome cycle+++GO:0051301///cell division+++GO:0090166///Golgi disassembly+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0010243///response to organonitrogen compound+++GO:0070301///cellular response to hydrogen peroxide+++GO:0034501///protein localization to kinetochore+++GO:0042493///response to drug+++GO:0006281///DNA repair+++GO:0043066///negative regulation of apoptotic process+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0046718///viral entry into host cell+++GO:0000278///mitotic cell cycle+++GO:1905448///positive regulation of mitochondrial ATP synthesis coupled electron transport+++GO:0033160///positive regulation of protein import into nucleus, translocation+++GO:0046686///response to cadmium ion+++GO:0055015///ventricular cardiac muscle cell development+++GO:0009636///response to toxic substance+++GO:0016310///phosphorylation+++GO:0014823///response to activity","cyclin dependent kinase 1","[CDK1_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 1; Short=CDK1; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cell division control protein 2 homolog; AltName: Full=Cell division protein kinase 1; AltName: Full=p34 protein kinase;+++[A0A024QZJ8_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2, G1 to S and G2 to M, isoform CRA_c {ECO:0000313|EMBL:EAW54207.1};+++[A0A024QZP7_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2, G1 to S and G2 to M, isoform CRA_a {ECO:0000313|EMBL:EAW54209.1}; SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000397973};+++[A0A087WZZ9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000482996};+++[B7Z3D6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50170, highly similar to Cell division control protein 2 homolog {ECO:0000313|EMBL:BAH12172.1};+++[E5RIU6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000430665}; Flags: Fragment;+++[I6L9I5_HUMAN|Unreviewed]SubName: Full=CDC2 protein {ECO:0000313|EMBL:AAI07751.1};"]
[9830,"'TRIM14'",244,115,149,169.333333333333,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0002376///immune system process+++GO:0032897///negative regulation of viral transcription+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0045087///innate immune response","tripartite motif containing 14","[TRI14_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 14;+++[A0A024R143_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_c {ECO:0000313|EMBL:EAW58876.1};+++[A0A024R165_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_a {ECO:0000313|EMBL:EAW58878.1};+++[F2Z2M2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 14 {ECO:0000313|Ensembl:ENSP00000428805};"]
[9831,"'ZNF623'",205,139,193,179,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,"R01724///5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming) Nicotinate D-ribonucleotide + Diphosphate + ADP + Orthophosphate <=> Nicotinate + 5-Phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + H+","GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 623","[ZN623_HUMAN|Reviewed]RecName: Full=Zinc finger protein 623;+++[A0A0A0MT18_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000411139};+++[A0A0J9YW98_HUMAN|Unreviewed]SubName: Full=HCG31704 {ECO:0000313|EMBL:EAW82216.1}; SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000487869};"]
[9832,"'JAKMIP2'",14.08,18,16,16.0266666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019900///kinase binding",null,"janus kinase and microtubule interacting protein 2","[JKIP2_HUMAN|Reviewed]RecName: Full=Janus kinase and microtubule-interacting protein 2; AltName: Full=CTCL tumor antigen HD-CL-04; AltName: Full=Neuroendocrine long coiled-coil protein 1;+++[Q05DV4_HUMAN|Unreviewed]SubName: Full=JAKMIP2 protein {ECO:0000313|EMBL:AAH03189.1}; Flags: Fragment;"]
[9833,"'MELK'",18,13,7,12.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005938///cell cortex+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005509///calcium ion binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0008289///lipid binding+++GO:0005524///ATP binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0030097///hemopoiesis+++GO:0016310///phosphorylation+++GO:0006915///apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0008283///cell proliferation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0007049///cell cycle+++GO:0061351///neural precursor cell proliferation","maternal embryonic leucine zipper kinase","[MELK_HUMAN|Reviewed]RecName: Full=Maternal embryonic leucine zipper kinase; Short=hMELK; EC=2.7.11.1; AltName: Full=Protein kinase Eg3; Short=pEg3 kinase; AltName: Full=Protein kinase PK38; Short=hPK38; AltName: Full=Tyrosine-protein kinase MELK; EC=2.7.10.2;+++[A0A0D9SFB9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486459};+++[A0A0D9SFF9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486558};+++[A0A0D9SFL8_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486717};+++[A0A0D9SGI4_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000487536}; Flags: Fragment;+++[B7Z1G6_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00804148}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00804148};"]
[9836,"'LCMT2'",153,153,144,150,{"$nulls":3},"R10586///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-carboxypropyl]wyosine37-O}-methyltransferase   7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine <=> 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-homocysteine+++R10587///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methyltransferase (carbon dioxide-adding)   7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine + CO2 <=> Wybutosine in tRNA(Phe) + S-Adenosyl-L-homocysteine","GO:0005737///cytoplasm","GO:0008168///methyltransferase activity+++GO:0018423///protein C-terminal leucine carboxyl O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008175///tRNA methyltransferase activity","GO:0008033///tRNA processing+++GO:0006400///tRNA modification+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0031591///wybutosine biosynthetic process+++GO:0006481///C-terminal protein methylation","leucine carboxyl methyltransferase 2","[TYW4_HUMAN|Reviewed]RecName: Full=tRNA wybutosine-synthesizing protein 4; Short=tRNA yW-synthesizing protein 4; EC=2.1.1.290; EC=2.3.1.231; AltName: Full=Leucine carboxyl methyltransferase 2; AltName: Full=tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; AltName: Full=tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase;+++[H3BU01_HUMAN|Unreviewed]SubName: Full=tRNA wybutosine-synthesizing protein 4 {ECO:0000313|Ensembl:ENSP00000457403};"]
[9837,"'GINS1'",6,15,12,11,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00286///GINS complex",null,"GO:0005634///nucleus+++GO:0000811///GINS complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0043138///3'-5' DNA helicase activity","GO:0006271///DNA strand elongation involved in DNA replication+++GO:0001833///inner cell mass cell proliferation+++GO:1902983///DNA strand elongation involved in mitotic DNA replication+++GO:0032508///DNA duplex unwinding+++GO:0006260///DNA replication","GINS complex subunit 1","[PSF1_HUMAN|Reviewed]RecName: Full=DNA replication complex GINS protein PSF1; AltName: Full=GINS complex subunit 1;+++[L8ECJ2_HUMAN|Unreviewed]SubName: Full=Alternative protein GINS1 {ECO:0000313|EMBL:CCQ43662.1};"]
[9839,"'ZEB2'",559,355,465,459.666666666667,"05206///MicroRNAs in cancer","H00961///Posterior polymorphous corneal dystrophy (PPCD)+++H00908///Mowat-Wilson syndrome+++H00960///Fuchs corneal dystrophy (FECD)",null,null,"GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0019208///phosphatase regulator activity+++GO:0070412///R-SMAD binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0021957///corticospinal tract morphogenesis+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021766///hippocampus development+++GO:0097324///melanocyte migration+++GO:0001755///neural crest cell migration+++GO:0050772///positive regulation of axonogenesis+++GO:0021540///corpus callosum morphogenesis+++GO:0048066///developmental pigmentation+++GO:0043507///positive regulation of JUN kinase activity+++GO:1902748///positive regulation of lens fiber cell differentiation+++GO:0048668///collateral sprouting+++GO:0048598///embryonic morphogenesis+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0061373///mammillary axonal complex development+++GO:1903056///regulation of melanosome organization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021846///cell proliferation in forebrain+++GO:0007399///nervous system development+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development","zinc finger E-box binding homeobox 2","[ZEB2_HUMAN|Reviewed]RecName: Full=Zinc finger E-box-binding homeobox 2; AltName: Full=Smad-interacting protein 1; Short=SMADIP1; AltName: Full=Zinc finger homeobox protein 1b;+++[A0A0D9SF71_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486341};+++[A0A0D9SF74_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486346}; Flags: Fragment;+++[A0A0D9SG93_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487261};+++[A0A0D9SGG5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487476}; Flags: Fragment;+++[A0A1B0GTH3_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000489701}; Flags: Fragment;+++[A0A1B0GUM8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490175};+++[A0A1B0GV02_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490317};+++[A0A1B0GVV8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490673};+++[A0A1B0GW50_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490776};+++[A0A1B0GWA7_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490851};+++[A0A1B0GWI0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490934};+++[A0A1W2PS25_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000492572}; Flags: Fragment;+++[A0A1X7SC99_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490293}; Flags: Fragment;+++[A0A2R8YDQ8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000494820}; Flags: Fragment;+++[A0JP08_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|EMBL:AAI27102.1, ECO:0000313|Ensembl:ENSP00000302501};+++[C9JU62_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000400993}; Flags: Fragment;+++[C9JUQ1_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000399451}; Flags: Fragment;+++[E7ESP8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000376601}; Flags: Fragment;+++[E7EUW9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000395496}; Flags: Fragment;+++[E7EVG9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000387256}; Flags: Fragment;+++[H7C0G0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000394777};+++[Q53TD9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93276.1}; Flags: Fragment;+++[Q53TG0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93269.1}; Flags: Fragment;+++[Q60F94_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60928.1};+++[Q60F95_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60927.1};+++[Q9H4F4_HUMAN|Unreviewed]SubName: Full=Survival interacting protein 1 {ECO:0000313|EMBL:CAC16171.1}; Flags: Fragment;+++[U3KPV5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475267}; Flags: Fragment;+++[U3KPX6_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475329};+++[U3KQ33_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475502};+++[U3KQ51_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475553};"]
[984,"'CDK11B'",1027.89,1188.57,1031.9,1082.78666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016310///phosphorylation+++GO:0050684///regulation of mRNA processing+++GO:0001558///regulation of cell growth+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process","cyclin dependent kinase 11B","[CD11B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 11B; EC=2.7.11.22; AltName: Full=Cell division cycle 2-like protein kinase 1; Short=CLK-1; AltName: Full=Cell division protein kinase 11B; AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA; AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L1; AltName: Full=p58 CLK-1;+++[A0A087WYI9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000481846};+++[A0A087X1I0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000484222};+++[A0A0D9SEI3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485705};+++[A0A0D9SEN2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485849};+++[A0A0D9SER5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485937};+++[A4VCI5_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAI39778.1}; Flags: Fragment;+++[B4DII1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59025, moderately similar to PITSLRE serine/threonine-protein kinaseCDC2L1 {ECO:0000313|EMBL:BAG58493.1};+++[Q6PK02_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAH09375.1}; Flags: Fragment;"]
[9840,"'TESPA1'",0,0,1.07,0.356666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0008180///COP9 signalosome","GO:0005102///signaling receptor binding","GO:0010387///COP9 signalosome assembly+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0050862///positive regulation of T cell receptor signaling pathway","thymocyte expressed, positive selection associated 1","[TESP1_HUMAN|Reviewed]RecName: Full=Protein TESPA1; AltName: Full=Thymocyte-expressed positive selection-associated protein 1;+++[A0A024RB00_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_a {ECO:0000313|EMBL:EAW96798.1};+++[A0A024RB73_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_c {ECO:0000313|EMBL:EAW96800.1};+++[E9PHY9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436635}; Flags: Fragment;+++[E9PIN8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000435734}; Flags: Fragment;+++[E9PIT9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433895}; Flags: Fragment;+++[E9PM24_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433187}; Flags: Fragment;+++[E9PN46_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434811};+++[E9PPW8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436286}; Flags: Fragment;+++[H0YDP3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434039}; Flags: Fragment;+++[H0YEX3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436753}; Flags: Fragment;"]
[9841,"'ZBTB24'",164.95,140.17,133,146.04,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 24","[ZBT24_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 24; AltName: Full=Zinc finger protein 450;"]
[9842,"'PLEKHM1'",2224,2170,2087,2160.33333333333,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0010008///endosome membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane","GO:0046872///metal ion binding","GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0035556///intracellular signal transduction+++GO:0032418///lysosome localization+++GO:0045780///positive regulation of bone resorption+++GO:1900029///positive regulation of ruffle assembly","pleckstrin homology and RUN domain containing M1","[PKHM1_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family M member 1; Short=PH domain-containing family M member 1; AltName: Full=162 kDa adapter protein; Short=AP162;+++[J3KRL8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462065}; Flags: Fragment;+++[J3KRU0_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462160};+++[J3KS30_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462282};+++[K7EII8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000464766};+++[K7EMP2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000466589}; Flags: Fragment;+++[K7EPF2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467356}; Flags: Fragment;+++[K7EQ68_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467695}; Flags: Fragment;"]
[9843,"'HEPH'",153,170,120,147.666666666667,"00860///Porphyrin and chlorophyll metabolism+++04978///Mineral absorption",null,null,"R00078///Fe(II):oxygen oxidoreductase; Fe2+:oxygen   Oxygen + 4 Fe2+ + 4 H+ <=> 4 Fe3+ + 2 H2O","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005615///extracellular space","GO:0016491///oxidoreductase activity+++GO:0016722///oxidoreductase activity, oxidizing metal ions+++GO:0046872///metal ion binding+++GO:0008198///ferrous iron binding+++GO:0005507///copper ion binding+++GO:0004322///ferroxidase activity","GO:0006879///cellular iron ion homeostasis+++GO:0055114///oxidation-reduction process+++GO:0006825///copper ion transport+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0055072///iron ion homeostasis","hephaestin","[HEPH_HUMAN|Reviewed]RecName: Full=Hephaestin; EC=1.-.-.-; Flags: Precursor;+++[A0A0C4DG76_HUMAN|Unreviewed]SubName: Full=Hephaestin, isoform CRA_c {ECO:0000313|EMBL:EAX05387.1};+++[E7ES21_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000413211};+++[F8WBZ8_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000392319};+++[Q1HE23_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|EMBL:ABF47089.1};+++[Q5JZ07_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000396907}; Flags: Fragment;+++[Q5JZ08_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000398078}; Flags: Fragment;"]
[9844,"'ELMO1'",30,16,26,24,"05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++04062///Chemokine signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017124///SH3 domain binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0050690///regulation of defense response to virus by virus+++GO:0006909///phagocytosis+++GO:0030036///actin cytoskeleton organization+++GO:0016477///cell migration+++GO:0030029///actin filament-based process+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048870///cell motility+++GO:0006915///apoptotic process+++GO:0016601///Rac protein signal transduction+++GO:0006911///phagocytosis, engulfment","engulfment and cell motility 1","[ELMO1_HUMAN|Reviewed]RecName: Full=Engulfment and cell motility protein 1; AltName: Full=Protein ced-12 homolog;+++[A4D1X5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility 1 (Ced-12 homolog, C. elegans) {ECO:0000313|EMBL:EAL23978.1}; SubName: Full=Engulfment and cell motility 1, isoform CRA_c {ECO:0000313|EMBL:EAW94077.1}; SubName: Full=cDNA FLJ77700, highly similar to Homo sapiens engulfment and cell motility 1 (ELMO1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84473.1};+++[C9IZR8_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000406610}; Flags: Fragment;+++[C9J5X3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000397857}; Flags: Fragment;+++[C9JB20_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000391734}; Flags: Fragment;+++[C9JIW2_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000416090}; Flags: Fragment;+++[H7C0N5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000395933}; Flags: Fragment;+++[H7C0S6_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000396465}; Flags: Fragment;+++[H7C3P3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000413108}; Flags: Fragment;"]
[9846,"'GAB2'",1749,1456,1512,1572.33333333333,"05220///Chronic myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++04664///Fc epsilon RI signaling pathway+++04072///Phospholipase D signaling pathway+++04071///Sphingolipid signaling pathway+++04380///Osteoclast differentiation+++04014///Ras signaling pathway","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0005515///protein binding+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity","GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043306///positive regulation of mast cell degranulation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0007411///axon guidance","GRB2 associated binding protein 2","[GAB2_HUMAN|Reviewed]RecName: Full=GRB2-associated-binding protein 2; AltName: Full=GRB2-associated binder 2; AltName: Full=Growth factor receptor bound protein 2-associated protein 2; AltName: Full=pp100;+++[E9PJ26_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000431868}; Flags: Fragment;+++[E9PJE2_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000433762}; Flags: Fragment;"]
[9847,"'C2CD5'",203,188,185,192,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0001726///ruffle+++GO:0032587///ruffle membrane+++GO:0005815///microtubule organizing center","GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005544///calcium-dependent phospholipid binding","GO:0006906///vesicle fusion+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0046326///positive regulation of glucose import+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0065002///intracellular protein transmembrane transport+++GO:0031340///positive regulation of vesicle fusion+++GO:0032869///cellular response to insulin stimulus","C2 calcium dependent domain containing 5","[C2CD5_HUMAN|Reviewed]RecName: Full=C2 domain-containing protein 5; AltName: Full=C2 domain-containing phosphoprotein of 138 kDa;+++[A0A024RB03_HUMAN|Unreviewed]SubName: Full=KIAA0528, isoform CRA_b {ECO:0000313|EMBL:EAW96475.1};+++[B7ZLK1_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43860.1};+++[B7ZLK2_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43861.1};+++[H0YFC4_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000437935}; Flags: Fragment;+++[H0YFE9_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000438256}; Flags: Fragment;+++[H0YGU7_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000444857}; Flags: Fragment;"]
[9848,"'MFAP3L'",1711,1153,1477,1447,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"microfibril associated protein 3 like","[MFA3L_HUMAN|Reviewed]RecName: Full=Microfibrillar-associated protein 3-like; AltName: Full=Testis development protein NYD-SP9 {ECO:0000303|Ref.1}; Flags: Precursor;+++[D6R9L7_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423549}; Flags: Fragment;+++[D6RAB5_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000422791}; Flags: Fragment;+++[D6RCC0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423802}; Flags: Fragment;+++[D6RCF0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423722}; Flags: Fragment;+++[D6RDM6_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000425303}; Flags: Fragment;+++[D6RGZ8_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000426247}; Flags: Fragment;"]
[9849,"'ZNF518A'",97,75,76,82.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04064///NF-kappa B signaling pathway+++05340///Primary immunodeficiency+++04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway","H00085///Agammaglobulinemias",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 518A","[Z518A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 518A;+++[A0A087WWK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 518A {ECO:0000313|Ensembl:ENSP00000480280}; Flags: Fragment;"]
[9851,"'KIAA0753'",233,146,239,206,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0034451///centriolar satellite+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:0007099///centriole replication+++GO:0071539///protein localization to centrosome","KIAA0753","[MOONR_HUMAN|Reviewed]RecName: Full=Protein moonraker {ECO:0000303|PubMed:26297806}; Short=MNR {ECO:0000303|PubMed:26297806}; AltName: Full=OFD1- and FOPNL-interacting protein {ECO:0000303|PubMed:26643951};+++[F6SFD5_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000444946}; Flags: Fragment;+++[I3L0P7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458247}; Flags: Fragment;+++[I3L1P2_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458983}; Flags: Fragment;+++[I3L2A7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000459530}; Flags: Fragment;+++[I3L341_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460156}; Flags: Fragment;+++[I3L3Y0_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460816};"]
[9852,"'EPM2AIP1'",534,454,538,508.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0032868///response to insulin+++GO:2000467///positive regulation of glycogen (starch) synthase activity+++GO:0045725///positive regulation of glycogen biosynthetic process","EPM2A interacting protein 1","[EPMIP_HUMAN|Reviewed]RecName: Full=EPM2A-interacting protein 1; AltName: Full=Laforin-interacting protein;+++[A0A096LNL1_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485091}; Flags: Fragment;+++[A0A096LPB0_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485489}; Flags: Fragment;"]
[9853,"'RUSC2'",2951,2990,2802,2914.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0017137///Rab GTPase binding","GO:0008150///biological_process","RUN and SH3 domain containing 2","[RUSC2_HUMAN|Reviewed]RecName: Full=Iporin; AltName: Full=Interacting protein of Rab1; AltName: Full=RUN and SH3 domain-containing protein 2;"]
[9854,"'C2CD2L'",658,611,599,622.666666666667,"00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome+++H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0098592///cytoplasmic side of apical plasma membrane+++GO:0016020///membrane+++GO:0032541///cortical endoplasmic reticulum","GO:0008526///phosphatidylinositol transporter activity+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0043559///insulin binding+++GO:0005548///phospholipid transporter activity","GO:0015914///phospholipid transport+++GO:0006869///lipid transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus","C2CD2 like","[C2C2L_HUMAN|Reviewed]RecName: Full=Phospholipid transfer protein C2CD2L {ECO:0000305}; AltName: Full=C2 domain-containing protein 2-like {ECO:0000312|HGNC:HGNC:29000}; Short=C2CD2-like; AltName: Full=Transmembrane protein 24 {ECO:0000303|PubMed:28209843};+++[E9PK05_HUMAN|Unreviewed]SubName: Full=Phospholipid transfer protein C2CD2L {ECO:0000313|Ensembl:ENSP00000433600};+++[Q6DHX1_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH75832.1}; Flags: Fragment;+++[Q9BTM2_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH03598.2};"]
[9855,"'FARP2'",195,170,166,177,"04015///Rap1 signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030316///osteoclast differentiation+++GO:0033623///regulation of integrin activation+++GO:0031532///actin cytoskeleton reorganization+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0022405///hair cycle process+++GO:0016601///Rac protein signal transduction+++GO:0071800///podosome assembly+++GO:0007155///cell adhesion+++GO:0035023///regulation of Rho protein signal transduction+++GO:0016322///neuron remodeling","FERM, ARH/RhoGEF and pleckstrin domain protein 2","[FARP2_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2; AltName: Full=FERM domain-including RhoGEF; Short=FIR; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2; AltName: Full=Pleckstrin homology domain-containing family C member 3; Short=PH domain-containing family C member 3;+++[A0A2X0SSL3_HUMAN|Unreviewed]SubName: Full=FARP2 {ECO:0000313|EMBL:SPT35757.1}; Flags: Fragment;+++[C9JVQ5_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393376}; Flags: Fragment;+++[C9JWM9_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000388167}; Flags: Fragment;+++[H7C210_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000403437}; Flags: Fragment;+++[H7C3E4_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000411353}; Flags: Fragment;+++[H7C3M7_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000412772}; Flags: Fragment;+++[H7C447_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415474}; Flags: Fragment;"]
[9856,"'KIAA0319'",21,15,15,17,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0031901///early endosome membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0007399///nervous system development+++GO:2000171///negative regulation of dendrite development+++GO:0001764///neuron migration+++GO:0007275///multicellular organism development+++GO:0061024///membrane organization","KIAA0319","[K0319_HUMAN|Reviewed]RecName: Full=Dyslexia-associated protein KIAA0319; Flags: Precursor;+++[A0A087X0U9_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319 {ECO:0000313|Ensembl:ENSP00000483665};+++[L8E9P4_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0319 {ECO:0000313|EMBL:CCQ43461.1};"]
[9857,"'CEP350'",421,213,328,320.666666666667,{"$nulls":4},"GO:0005819///spindle+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0034453///microtubule anchoring","centrosomal protein 350","[CE350_HUMAN|Reviewed]RecName: Full=Centrosome-associated protein 350 {ECO:0000305}; Short=Cep350; AltName: Full=Centrosome-associated protein of 350 kDa {ECO:0000303|Ref.1};+++[A0A024R914_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 350kDa, isoform CRA_a {ECO:0000313|EMBL:EAW91073.1};+++[A2A4F6_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000350016}; Flags: Fragment;+++[E9PIK0_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000435808}; Flags: Fragment;+++[H0Y6Q4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000407044}; Flags: Fragment;+++[H0Y7F7_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000412460}; Flags: Fragment;+++[H0YD38_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000432910}; Flags: Fragment;+++[L8ECF2_HUMAN|Unreviewed]SubName: Full=Alternative protein CEP350 {ECO:0000313|EMBL:CCQ43462.1};+++[Q05D72_HUMAN|Unreviewed]SubName: Full=CEP350 protein {ECO:0000313|EMBL:AAH17847.1}; Flags: Fragment;+++[Q5T2X4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000401608}; Flags: Fragment;+++[Q5T2X5_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000409395}; Flags: Fragment;"]
[9858,"'PPP1R26'",304,250,318,290.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding","GO:0010923///negative regulation of phosphatase activity+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","protein phosphatase 1 regulatory subunit 26","[PPR26_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1 regulatory subunit 26;+++[A0A024R8E9_HUMAN|Unreviewed]SubName: Full=KIAA0649, isoform CRA_a {ECO:0000313|EMBL:EAW88151.1};"]
[9859,"'CEP170'",1448,877,919,1081.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0120103///centriolar subdistal appendage+++GO:0005819///spindle+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule","GO:0005515///protein binding",null,"centrosomal protein 170","[CE170_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 170 kDa; Short=Cep170; AltName: Full=KARP-1-binding protein; Short=KARP1-binding protein;+++[A6H8X9_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI46791.1};+++[B2RTS4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI40795.1};+++[E5RFU8_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427944}; Flags: Fragment;+++[E5RG47_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427843}; Flags: Fragment;+++[E5RGW7_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430112}; Flags: Fragment;+++[E5RIH6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428400}; Flags: Fragment;+++[E5RJT5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428183}; Flags: Fragment;+++[E7EMW0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427842};+++[E7EWM2_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430142};+++[H0Y2V6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000338161}; Flags: Fragment;+++[H0Y4T4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000394002}; Flags: Fragment;+++[H0YB66_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428777}; Flags: Fragment;+++[H0YB92_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428996}; Flags: Fragment;+++[Q6AZE1_HUMAN|Unreviewed]SubName: Full=CEP170 protein {ECO:0000313|EMBL:AAH78155.1}; Flags: Fragment;"]
[9860,"'LRIG2'",179.02,176.98,182.75,179.583333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030426///growth cone+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0097708///intracellular vesicle","GO:0005102///signaling receptor binding","GO:0048681///negative regulation of axon regeneration+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0010640///regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:2001222///regulation of neuron migration+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0048679///regulation of axon regeneration+++GO:0060384///innervation+++GO:0007605///sensory perception of sound","leucine rich repeats and immunoglobulin like domains 2","[LRIG2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 2; Short=LIG-2; Flags: Precursor;"]
[9861,"'PSMD6'",607,564,583,584.666666666667,"03050///Proteasome+++05169///Epstein-Barr virus infection","H00063///Spinocerebellar ataxia (SCA)","M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0005576///extracellular region+++GO:0000502///proteasome complex+++GO:1904813///ficolin-1-rich granule lumen+++GO:0022624///proteasome accessory complex+++GO:0005829///cytosol+++GO:0005838///proteasome regulatory particle+++GO:0034774///secretory granule lumen+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0016887///ATPase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0043687///post-translational protein modification+++GO:0050790///regulation of catalytic activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043312///neutrophil degranulation","proteasome 26S subunit, non-ATPase 6","[PSMD6_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 6; AltName: Full=26S proteasome regulatory subunit RPN7; AltName: Full=26S proteasome regulatory subunit S10; AltName: Full=Breast cancer-associated protein SGA-113M; AltName: Full=Phosphonoformate immuno-associated protein 4; AltName: Full=Proteasome regulatory particle subunit p44S10; AltName: Full=p42A;+++[B3KT66_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, isoform CRA_c {ECO:0000313|EMBL:EAW65426.1}; SubName: Full=cDNA FLJ37740 fis, clone BRHIP2021870, highly similar to 26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|EMBL:BAG52978.1};+++[C9J0E9_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418887}; Flags: Fragment;+++[C9J7B7_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418303}; Flags: Fragment;+++[H7C531_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418843}; Flags: Fragment;"]
[9862,"'MED24'",1680,1778,1776,1744.66666666667,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0042809///vitamin D receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0003712///transcription coregulator activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0038023///signaling receptor activity","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0030521///androgen receptor signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated","mediator complex subunit 24","[MED24_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 24; AltName: Full=Activator-recruited cofactor 100 kDa component; Short=ARC100; AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 4; Short=CRSP complex subunit 4; AltName: Full=Mediator complex subunit 24; AltName: Full=Thyroid hormone receptor-associated protein 4; AltName: Full=Thyroid hormone receptor-associated protein complex 100 kDa component; Short=Trap100; Short=hTRAP100; AltName: Full=Vitamin D3 receptor-interacting protein complex 100 kDa component; Short=DRIP100;+++[A0A0B4J1W0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000377684}; SubName: Full=Thyroid hormone receptor associated protein 4, isoform CRA_a {ECO:0000313|EMBL:EAW60629.1};+++[B4DDR8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463751}; SubName: Full=cDNA FLJ59464, highly similar to Thyroid hormone receptor-associated proteincomplex 100 kDa component {ECO:0000313|EMBL:BAG56829.1};+++[B9TX62_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i2 {ECO:0000313|EMBL:ACB88915.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000393464}; Flags: Fragment;+++[B9TX63_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i3 {ECO:0000313|EMBL:ACB88916.1}; Flags: Fragment;+++[B9TX64_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i4 {ECO:0000313|EMBL:ACB88917.1}; Flags: Fragment;+++[B9TX65_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i5 {ECO:0000313|EMBL:ACB88918.1}; Flags: Fragment;+++[B9TX66_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i6 {ECO:0000313|EMBL:ACB88919.1}; Flags: Fragment;+++[B9TX67_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i7 {ECO:0000313|EMBL:ACB88920.1}; Flags: Fragment;+++[B9TX68_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i8 {ECO:0000313|EMBL:ACB88921.1}; Flags: Fragment;+++[B9TX69_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i9 {ECO:0000313|EMBL:ACB88922.1}; Flags: Fragment;+++[B9TX70_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i10 {ECO:0000313|EMBL:ACB88923.1}; Flags: Fragment;+++[B9TX71_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i11 {ECO:0000313|EMBL:ACB88924.1}; Flags: Fragment;+++[B9TX72_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i12 {ECO:0000313|EMBL:ACB88925.1}; Flags: Fragment;+++[B9TX73_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i13 {ECO:0000313|EMBL:ACB88926.1}; Flags: Fragment;+++[B9TX74_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i14 {ECO:0000313|EMBL:ACB88927.1}; Flags: Fragment;+++[B9TX75_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i15 {ECO:0000313|EMBL:ACB88928.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000482676};+++[B9TX76_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i16 {ECO:0000313|EMBL:ACB88929.1};+++[E9PFL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000392276}; Flags: Fragment;+++[F5GY88_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000440100};+++[F5H0M2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438767}; Flags: Fragment;+++[F5H2D6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438630}; Flags: Fragment;+++[F5H3E6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000439148};+++[F5H5K2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000443344}; Flags: Fragment;+++[H0YEG1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000435760}; Flags: Fragment;+++[J3KSL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462539}; Flags: Fragment;+++[J3KSU0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462646}; Flags: Fragment;+++[J3KTL3_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463043}; Flags: Fragment;+++[J3QLC0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463480}; Flags: Fragment;+++[J3QLC2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463484}; Flags: Fragment;+++[J3QLF8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463528}; Flags: Fragment;+++[J3QLV7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463724}; Flags: Fragment;+++[J3QRH9_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000464225}; Flags: Fragment;"]
[9863,"'MAGI2'",221.85,179,236,212.283333333333,"04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway","H01657///Nephrotic syndrome",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005923///bicellular tight junction+++GO:0045202///synapse+++GO:0005768///endosome+++GO:0043005///neuron projection+++GO:0014069///postsynaptic density+++GO:0005770///late endosome+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030425///dendrite","GO:0030159///receptor signaling complex scaffold activity+++GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0070699///type II activin receptor binding+++GO:0070697///activin receptor binding+++GO:0016301///kinase activity+++GO:0046332///SMAD binding","GO:0007399///nervous system development+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0072015///glomerular visceral epithelial cell development+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0030336///negative regulation of cell migration+++GO:0002092///positive regulation of receptor internalization+++GO:0008285///negative regulation of cell proliferation+++GO:0043113///receptor clustering+++GO:0038180///nerve growth factor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0060395///SMAD protein signal transduction+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0071850///mitotic cell cycle arrest+++GO:0007165///signal transduction+++GO:0051291///protein heterooligomerization+++GO:0016310///phosphorylation+++GO:0003402///planar cell polarity pathway involved in axis elongation","membrane associated guanylate kinase, WW and PDZ domain containing 2","[MAGI2_HUMAN|Reviewed]RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; AltName: Full=Atrophin-1-interacting protein 1; Short=AIP-1; AltName: Full=Atrophin-1-interacting protein A; AltName: Full=Membrane-associated guanylate kinase inverted 2; Short=MAGI-2;+++[A0A0D9SET0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000485970};+++[A0A0D9SEY4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486131};+++[A0A0D9SEZ7_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486154}; Flags: Fragment;+++[A0A0D9SF86_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486379}; Flags: Fragment;+++[A0A0D9SFP3_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486774};+++[A0A0D9SFY9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487001}; Flags: Fragment;+++[A0A0D9SGF2_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487435};+++[A0A0D9SGF8_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_c {ECO:0000313|EMBL:EAW77024.1}; SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487448};+++[A0A0D9SGI1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487526};+++[A0A0E3D6M1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000441603};+++[A0A0U1RRH4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489533}; Flags: Fragment;+++[A0A1B0GTC0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489633};+++[A0A1B0GTH8_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489709}; Flags: Fragment;+++[A0A1B0GUF0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490080};+++[A0A1B0GUI9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490128}; Flags: Fragment;+++[A0A1B0GUV4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490259};+++[A0A1B0GVS0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490629}; Flags: Fragment;+++[A0A1B0GVS6_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490637};+++[B7Z4H4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61315, highly similar to Membrane-associated guanylate kinase, WW andPDZ domain-containing protein 2 {ECO:0000313|EMBL:BAH12560.1};+++[D6W5N0_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_b {ECO:0000313|EMBL:EAW77023.1};+++[E7EWI0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000428389};"]
[9865,"'TRIL'",49,33,99,60.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0046696///lipopolysaccharide receptor complex","GO:0001530///lipopolysaccharide binding","GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response+++GO:0002718///regulation of cytokine production involved in immune response","TLR4 interactor with leucine rich repeats","[TRIL_HUMAN|Reviewed]RecName: Full=TLR4 interactor with leucine rich repeats; AltName: Full=Leucine-rich repeat-containing protein KIAA0644; Flags: Precursor;"]
[9866,"'TRIM66'",207,190.22,209.99,202.403333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016235///aggresome","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0045892///negative regulation of transcription, DNA-templated","tripartite motif containing 66","[TRI66_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 66;+++[A0A2R8YE93_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000494157}; Flags: Fragment;+++[A0A2R8YEA1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000495413};+++[B5MCJ9_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000384876};+++[H0YF52_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000437234}; Flags: Fragment;"]
[9867,"'PJA2'",1423,947,1118,1162.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045202///synapse+++GO:0005783///endoplasmic reticulum+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0045111///intermediate filament cytoskeleton+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm","GO:0034236///protein kinase A catalytic subunit binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity","GO:0006954///inflammatory response+++GO:0035329///hippo signaling+++GO:0016567///protein ubiquitination+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0045087///innate immune response+++GO:0043030///regulation of macrophage activation+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0010738///regulation of protein kinase A signaling+++GO:0007616///long-term memory","praja ring finger ubiquitin ligase 2","[PJA2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Praja-2; Short=Praja2; EC=2.3.2.27; AltName: Full=RING finger protein 131; AltName: Full=RING-type E3 ubiquitin transferase Praja-2 {ECO:0000305};"]
[9868,"'TOMM70'",674,638,579,630.333333333333,{"$nulls":4},"GO:0005742///mitochondrial outer membrane translocase complex+++GO:0070062///extracellular exosome+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding","GO:0071806///protein transmembrane transport+++GO:0006626///protein targeting to mitochondrion","translocase of outer mitochondrial membrane 70","[TOM70_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM70; AltName: Full=Mitochondrial precursor proteins import receptor; AltName: Full=Translocase of outer membrane 70 kDa subunit; AltName: Full=Translocase of outer mitochondrial membrane protein 70 {ECO:0000312|HGNC:HGNC:11985};"]
[9869,"'SETDB1'",466,423,501,463.333333333333,"04550///Signaling pathways regulating pluripotency of stem cells+++00310///Lysine degradation",null,null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm","GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:1990841///promoter-specific chromatin binding+++GO:0016740///transferase activity","GO:0045471///response to ethanol+++GO:0032259///methylation+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0006325///chromatin organization+++GO:0033273///response to vitamin+++GO:0007265///Ras protein signal transduction+++GO:0034968///histone lysine methylation","SET domain bifurcated 1","[SETB1_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETDB1; EC=2.1.1.43; AltName: Full=ERG-associated protein with SET domain; Short=ESET; AltName: Full=Histone H3-K9 methyltransferase 4; Short=H3-K9-HMTase 4; AltName: Full=Lysine N-methyltransferase 1E; AltName: Full=SET domain bifurcated 1;+++[B0QZE6_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000409379}; Flags: Fragment;+++[E9PAP1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357960};+++[E9PQM8_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000436148}; Flags: Fragment;+++[E9PRF4_HUMAN|Unreviewed]RecName: Full=Histone-lysine N-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00906}; EC=2.1.1.43 {ECO:0000256|PROSITE-ProRule:PRU00906}; Flags: Fragment;+++[E9PS59_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000435922}; Flags: Fragment;+++[X6R732_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357959};+++[X6RHV1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000407831}; Flags: Fragment;"]
[987,"'LRBA'",1047,760,828,878.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0008150///biological_process","LPS responsive beige-like anchor protein","[LRBA_HUMAN|Reviewed]RecName: Full=Lipopolysaccharide-responsive and beige-like anchor protein; AltName: Full=Beige-like protein; AltName: Full=CDC4-like protein;+++[E9PEM5_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000422180};+++[H0Y9N9_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000424640}; Flags: Fragment;+++[H0YA17_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000425852}; Flags: Fragment;+++[H0YAC6_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000426669}; Flags: Fragment;+++[Q6P1X2_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH64834.1};+++[Q969R7_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH12535.2}; Flags: Fragment;"]
[9870,"'AREL1'",1163,872,987,1007.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0006915///apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process","apoptosis resistant E3 ubiquitin protein ligase 1","[AREL1_HUMAN|Reviewed]RecName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1; EC=2.3.2.26; AltName: Full=Apoptosis-resistant HECT-type E3 ubiquitin transferase 1;+++[G3V245_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450458}; Flags: Fragment;+++[G3V2B5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450557};+++[G3V506_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452101}; Flags: Fragment;+++[G3V5P7_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452456};+++[H0YJ67_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450901}; Flags: Fragment;+++[H0YJ69_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450912}; Flags: Fragment;+++[H0YJF1_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451375}; Flags: Fragment;+++[H0YJK5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451710}; Flags: Fragment;+++[L8E7E7_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0317 {ECO:0000313|EMBL:CCQ43054.1};"]
[9871,"'SEC24D'",1440,1212,992,1214.66666666667,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0030127///COPII vesicle coat+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum","GO:0000149///SNARE binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0090110///cargo loading into COPII-coated vesicle+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0016192///vesicle-mediated transport+++GO:0001701///in utero embryonic development+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I","SEC24 homolog D, COPII coat complex component","[SC24D_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24D {ECO:0000305}; AltName: Full=SEC24-related protein D;+++[A8K6V0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78676, highly similar to Homo sapiens SEC24 related gene family, member D (SEC24D), mRNA {ECO:0000313|EMBL:BAF84454.1};+++[D6RAE2_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000422717};+++[D6RBM1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000424085};+++[D6RGJ5_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000426309}; Flags: Fragment;+++[E9PC44_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43974 fis, clone TESTI4018101, highly similar to Protein transport protein Sec24D {ECO:0000313|EMBL:BAG54271.1};+++[E9PDM8_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000425491};+++[E9PG84_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000427249};+++[Q49AI3_HUMAN|Unreviewed]SubName: Full=SEC24D protein {ECO:0000313|EMBL:AAH37736.1};+++[Q4W5D3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEC24D {ECO:0000313|EMBL:AAY40935.1}; Flags: Fragment;"]
[9873,"'FCHSD2'",258,242,256,252,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0055037///recycling endosome","GO:0005515///protein binding","GO:0007274///neuromuscular synaptic transmission+++GO:0030833///regulation of actin filament polymerization","FCH and double SH3 domains 2","[FCSD2_HUMAN|Reviewed]RecName: Full=F-BAR and double SH3 domains protein 2; AltName: Full=Carom; AltName: Full=SH3 multiple domains protein 3;+++[A0A024R5H2_HUMAN|Unreviewed]SubName: Full=FCH and double SH3 domains 2, isoform CRA_a {ECO:0000313|EMBL:EAW74881.1};+++[B8ZZW8_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386903};+++[C9JM66_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000408706}; Flags: Fragment;+++[E7ENZ2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000402972};+++[E9PG19_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386987};+++[H0Y6M2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000406420}; Flags: Fragment;+++[H0YG35_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000441616}; Flags: Fragment;"]
[9874,"'TLK1'",648,509,550,569,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006325///chromatin organization+++GO:0001672///regulation of chromatin assembly or disassembly+++GO:0007049///cell cycle+++GO:0006886///intracellular protein transport","tousled like kinase 1","[TLK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase tousled-like 1; EC=2.7.11.1; AltName: Full=PKU-beta; AltName: Full=Tousled-like kinase 1;+++[B3KRP1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000387313}; SubName: Full=Tousled-like kinase 1, isoform CRA_b {ECO:0000313|EMBL:EAX11221.1}; SubName: Full=cDNA FLJ34656 fis, clone KIDNE2018352, highly similar to Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|EMBL:BAG52453.1};+++[C9JWT6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000393165}; Flags: Fragment;+++[F8W7X8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000352810};+++[Q53TE4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAY15077.1}; Flags: Fragment;+++[Q53TF9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAX93162.1}; Flags: Fragment;"]
[9875,"'URB1'",947,715,808,823.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0008150///biological_process+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","URB1 ribosome biogenesis homolog","[NPA1P_HUMAN|Reviewed]RecName: Full=Nucleolar pre-ribosomal-associated protein 1; AltName: Full=Nucleolar protein 254 kDa; AltName: Full=URB1 ribosome biogenesis 1 homolog;"]
[9877,"'ZC3H11A'",1776.73,1556.02,1616.07,1649.60666666667,{"$nulls":4},"GO:0000346///transcription export complex+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003729///mRNA binding","GO:0006405///RNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031124///mRNA 3'-end processing+++GO:0051028///mRNA transport","zinc finger CCCH-type containing 11A","[ZC11A_HUMAN|Reviewed]RecName: Full=Zinc finger CCCH domain-containing protein 11A;+++[A0A1W2PPR9_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000491483};+++[C9J0L0_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000406531}; Flags: Fragment;+++[E9PBY7_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000415072}; Flags: Fragment;+++[E9PQ61_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000432602};+++[Q0D2N5_HUMAN|Unreviewed]SubName: Full=ZC3H11A protein {ECO:0000313|EMBL:AAH46137.1};"]
[9878,"'TOX4'",1356,1467,1522,1448.33333333333,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0030175///filopodium+++GO:0031225///anchored component of membrane+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0005576///extracellular region+++GO:0042995///cell projection+++GO:0032432///actin filament bundle+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0042627///chylomicron+++GO:0001891///phagocytic cup+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0032587///ruffle membrane+++GO:0002102///podosome+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0015629///actin cytoskeleton+++GO:0000785///chromatin+++GO:0034361///very-low-density lipoprotein particle+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0001726///ruffle","GO:0008201///heparin binding+++GO:0004806///triglyceride lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003779///actin binding+++GO:0051020///GTPase binding+++GO:0004465///lipoprotein lipase activity+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0034185///apolipoprotein binding+++GO:0051015///actin filament binding+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0004620///phospholipase activity+++GO:0017129///triglyceride binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding","GO:0051639///actin filament network formation+++GO:0050729///positive regulation of inflammatory response+++GO:0022617///extracellular matrix disassembly+++GO:0019433///triglyceride catabolic process+++GO:0031100///animal organ regeneration+++GO:0006641///triglyceride metabolic process+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0044319///wound healing, spreading of cells+++GO:0006644///phospholipid metabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0070328///triglyceride homeostasis+++GO:0016477///cell migration+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0002286///T cell activation involved in immune response+++GO:0009409///response to cold+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0010737///protein kinase A signaling+++GO:0071803///positive regulation of podosome assembly+++GO:0034371///chylomicron remodeling+++GO:0006633///fatty acid biosynthetic process+++GO:0033157///regulation of intracellular protein transport+++GO:0016042///lipid catabolic process+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0090197///positive regulation of chemokine secretion+++GO:0042632///cholesterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0009617///response to bacterium+++GO:0042493///response to drug+++GO:0009749///response to glucose+++GO:0010886///positive regulation of cholesterol storage+++GO:0051017///actin filament bundle assembly+++GO:0006357///regulation of transcription by RNA polymerase II","TOX high mobility group box family member 4","[TOX4_HUMAN|Reviewed]RecName: Full=TOX high mobility group box family member 4; AltName: Full=Epidermal Langerhans cell protein LCP1;+++[C9J919_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000406196}; Flags: Fragment;+++[C9JNL1_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000402195}; Flags: Fragment;+++[F8WBE8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000389333};+++[F8WC04_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392234};+++[F8WCL8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392482};+++[Q5TBN3_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000408052}; Flags: Fragment;+++[Q5TBN5_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000402157}; Flags: Fragment;"]
[9879,"'DDX46'",714,630,607,650.333333333333,"03040///Spliceosome",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","DEAD-box helicase 46","[DDX46_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX46; EC=3.6.4.13; AltName: Full=DEAD box protein 46; AltName: Full=PRP5 homolog;+++[A0A0C4DG89_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000416534};+++[D3DQA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_a {ECO:0000313|EMBL:EAW62242.1};+++[D6RJA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_b {ECO:0000313|EMBL:EAW62239.1}; SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000427290};+++[H0Y9U3_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000425073}; Flags: Fragment;+++[H0YAD5_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000426767}; Flags: Fragment;+++[Q0VGL8_HUMAN|Unreviewed]SubName: Full=DDX46 protein {ECO:0000313|EMBL:AAI05599.1}; Flags: Fragment;"]
[988,"'CDC5L'",619,561,564,581.333333333333,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0016020///membrane+++GO:0000974///Prp19 complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005662///DNA replication factor A complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0016607///nuclear speck+++GO:0032993///protein-DNA complex+++GO:0071013///catalytic step 2 spliceosome","GO:0001222///transcription corepressor binding+++GO:0008157///protein phosphatase 1 binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0043522///leucine zipper domain binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0071987///WD40-repeat domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0000278///mitotic cell cycle+++GO:0000398///mRNA splicing, via spliceosome+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0008380///RNA splicing+++GO:0006974///cellular response to DNA damage stimulus+++GO:1904568///cellular response to wortmannin+++GO:0072422///signal transduction involved in DNA damage checkpoint+++GO:0007049///cell cycle+++GO:0071352///cellular response to interleukin-2+++GO:1990646///cellular response to prolactin+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006397///mRNA processing","cell division cycle 5 like","[CDC5L_HUMAN|Reviewed]RecName: Full=Cell division cycle 5-like protein; Short=Cdc5-like protein; AltName: Full=Pombe cdc5-related protein;"]
[9880,"'ZBTB39'",120,98,128,115.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 39","[ZBT39_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 39;"]
[9881,"'TRANK1'",230,233,229,230.666666666667,{"$nulls":5},"GO:0005524///ATP binding",null,"tetratricopeptide repeat and ankyrin repeat containing 1","[TRNK1_HUMAN|Reviewed]RecName: Full=TPR and ankyrin repeat-containing protein 1; AltName: Full=Lupus brain antigen 1 homolog;+++[A0A096LPF5_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000485569}; Flags: Fragment;+++[A0A2R8Y7N6_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496256}; Flags: Fragment;+++[A0A2R8Y890_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496740}; Flags: Fragment;+++[A0A2R8Y8A3_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496771};+++[A0A2R8YEM9_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000494480};+++[L8EAQ6_HUMAN|Unreviewed]SubName: Full=Alternative protein TRANK1 {ECO:0000313|EMBL:CCQ43463.1};"]
[9882,"'TBC1D4'",67,47,47,53.6666666666667,"04931///Insulin resistance+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031982///vesicle+++GO:0005829///cytosol","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0016192///vesicle-mediated transport+++GO:0032869///cellular response to insulin stimulus+++GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport+++GO:0031339///negative regulation of vesicle fusion+++GO:0043547///positive regulation of GTPase activity","TBC1 domain family member 4","[TBCD4_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 4; AltName: Full=Akt substrate of 160 kDa; Short=AS160;+++[A0A024R637_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW80538.1};+++[Q5JU47_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 4 {ECO:0000313|Ensembl:ENSP00000396932}; Flags: Fragment;"]
[9883,"'POM121'",3327.98,2957.48,3255.94,3180.46666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0032389///MutLalpha complex","GO:0008139///nuclear localization sequence binding+++GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0017056///structural constituent of nuclear pore+++GO:0046872///metal ion binding","GO:0006606///protein import into nucleus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0016032///viral process+++GO:0006310///DNA recombination+++GO:0006298///mismatch repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus","POM121 transmembrane nucleoporin","[P121A_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;"]
[9884,"'LRRC37A'",103.67,69.17,81.4,84.7466666666667,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0030496///midbody","GO:0044877///protein-containing complex binding+++GO:0016887///ATPase activity+++GO:0017075///syntaxin-1 binding+++GO:0042623///ATPase activity, coupled+++GO:0000149///SNARE binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding","GO:0006813///potassium ion transport+++GO:0035494///SNARE complex disassembly+++GO:0015031///protein transport","leucine rich repeat containing 37A","[L37A1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 37A; Flags: Precursor;"]
[9885,"'OSBPL2'",618.24,572.46,567,585.9,"05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04151///PI3K-Akt signaling pathway+++01100///Metabolic pathways+++05200///Pathways in cancer+++05146///Amoebiasis+++05145///Toxoplasmosis+++05165///Human papillomavirus infection+++04510///Focal adhesion","H00586///Epidermolysis bullosa, junctional+++H00813///Laryngo onycho cutaneous syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0015248///sterol transporter activity+++GO:0005515///protein binding+++GO:0032934///sterol binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding","GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0006699///bile acid biosynthetic process","oxysterol binding protein like 2","[OSBL2_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 2; Short=ORP-2; Short=OSBP-related protein 2;+++[A0A087WTV1_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000478158}; Flags: Fragment;+++[A0A087WVV0_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000479702}; Flags: Fragment;+++[A0A2R8Y362_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;+++[A0A2R8Y429_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000493721};+++[A0A2R8Y5B9_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000494692};+++[A0A2R8Y5R1_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y690_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y703_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495611};+++[A0A2R8YD49_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YDU7_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YEX0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YFT0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG53_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495661}; Flags: Fragment;+++[A0A2R8YG59_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG95_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[B4DKJ8_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[E7ET92_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[H0Y7X4_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;"]
[9886,"'RHOBTB1'",477,405,426,436,"04120///Ubiquitin mediated proteolysis","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding","GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0043652///engulfment of apoptotic cell+++GO:0016477///cell migration+++GO:0007264///small GTPase mediated signal transduction+++GO:0000902///cell morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho related BTB domain containing 1","[RHBT1_HUMAN|Reviewed]RecName: Full=Rho-related BTB domain-containing protein 1;+++[A0A024QZL4_HUMAN|Unreviewed]SubName: Full=Rho-related BTB domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW54216.1};+++[Q567T3_HUMAN|Unreviewed]SubName: Full=RHOBTB1 protein {ECO:0000313|EMBL:AAH93035.1};"]
[9887,"'SMG7'",1457,1047,1153,1219,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton","GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0004540///ribonuclease activity+++GO:0070034///telomerase RNA binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0051721///protein phosphatase 2A binding","GO:0007004///telomere maintenance via telomerase+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0035303///regulation of dephosphorylation+++GO:0043487///regulation of RNA stability+++GO:0006406///mRNA export from nucleus","SMG7, nonsense mediated mRNA decay factor","[SMG7_HUMAN|Reviewed]RecName: Full=Protein SMG7; AltName: Full=EST1-like protein C; AltName: Full=SMG-7 homolog; Short=hSMG-7;+++[B1ALB4_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000388390}; Flags: Fragment;+++[D6R9J3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422056}; Flags: Fragment;+++[D6RAD0_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422742}; Flags: Fragment;+++[E9PBK2_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000400220};+++[E9PD50_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000356507};+++[E9PEK3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000410254};+++[Q6TV06_HUMAN|Unreviewed]SubName: Full=Breast cancer-associated antigen SGA-56M {ECO:0000313|EMBL:AAR25620.1}; SubName: Full=Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), isoform CRA_a {ECO:0000313|EMBL:EAW91154.1};"]
[9889,"'ZBED4'",555,422,450,475.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger BED-type containing 4","[ZBED4_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 4;"]
[989,"'SEPT7'",1173,986,980,1046.33333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016324///apical plasma membrane+++GO:0000775///chromosome, centromeric region+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0031105///septin complex+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0097730///non-motile cilium+++GO:0005634///nucleus+++GO:0031514///motile cilium+++GO:0005930///axoneme+++GO:0032160///septin filament array+++GO:0097227///sperm annulus+++GO:0032154///cleavage furrow+++GO:0001725///stress fiber+++GO:0005929///cilium+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0005198///structural molecule activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding","GO:0051301///cell division+++GO:0016476///regulation of embryonic cell shape+++GO:0000281///mitotic cytokinesis+++GO:0051291///protein heterooligomerization+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0060271///cilium assembly+++GO:0030154///cell differentiation+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:0000921///septin ring assembly","septin 7","[SEPT7_HUMAN|Reviewed]RecName: Full=Septin-7; AltName: Full=CDC10 protein homolog;+++[A0A023T695_HUMAN|Unreviewed]SubName: Full=Septin 7 variant 4 {ECO:0000313|EMBL:AHX84171.1};+++[A0A024RA87_HUMAN|Unreviewed]SubName: Full=Septin 7, isoform CRA_a {ECO:0000313|EMBL:EAW94060.1};+++[A0A0U1RQW0_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489192}; Flags: Fragment;+++[A0A0U1RRD1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489466}; Flags: Fragment;+++[A0A0U1RRE1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489480}; Flags: Fragment;+++[A0A0U1RRH9_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489538}; Flags: Fragment;+++[A0A0U1RRM2_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489596}; Flags: Fragment;+++[A8K3D0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75185 {ECO:0000313|EMBL:BAF83234.1};+++[B4DNE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52574, highly similar to Septin-7 {ECO:0000313|EMBL:BAG60206.1};+++[E7EPK1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000344868};+++[E7ES33_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000381993};+++[G3V1Q4_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000413507};+++[Q3B7A3_HUMAN|Unreviewed]SubName: Full=SEPT7 protein {ECO:0000313|EMBL:AAI07719.1}; Flags: Fragment;+++[Q5JXL7_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000444240};+++[Q8TC62_HUMAN|Unreviewed]SubName: Full=Septin 7 {ECO:0000313|EMBL:AAH25987.3};"]
[9890,"'PLPPR4'",3,0,5,2.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099061///integral component of postsynaptic density membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0016791///phosphatase activity+++GO:0016787///hydrolase activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0042577///lipid phosphatase activity","GO:0007409///axonogenesis+++GO:0046839///phospholipid dephosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0048839///inner ear development+++GO:0006644///phospholipid metabolic process","phospholipid phosphatase related 4","[PLPR4_HUMAN|Reviewed]RecName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000305}; EC=3.1.3.4; AltName: Full=Brain-specific phosphatidic acid phosphatase-like protein 1 {ECO:0000303|Ref.7}; AltName: Full=Lipid phosphate phosphatase-related protein type 4 {ECO:0000303|Ref.2}; AltName: Full=Plasticity-related gene 1 protein {ECO:0000305|PubMed:12730698}; Short=PRG-1 {ECO:0000303|PubMed:12730698};+++[Q3ZCT6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH41386.1}; Flags: Fragment;+++[Q86XM6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH42963.1}; Flags: Fragment;+++[W4VSQ3_HUMAN|Unreviewed]SubName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000313|Ensembl:ENSP00000359203};"]
[9891,"'NUAK1'",935,680,554,723,{"$nulls":4},"GO:0001650///fibrillar center+++GO:0015630///microtubule cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0002039///p53 binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0042127///regulation of cell proliferation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0007155///cell adhesion+++GO:0030155///regulation of cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035507///regulation of myosin-light-chain-phosphatase activity+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000772///regulation of cellular senescence","NUAK family kinase 1","[NUAK1_HUMAN|Reviewed]RecName: Full=NUAK family SNF1-like kinase 1; EC=2.7.11.1; AltName: Full=AMPK-related protein kinase 5; Short=ARK5; AltName: Full=Omphalocele kinase 1;+++[A0A024RBL3_HUMAN|Unreviewed]SubName: Full=NUAK family, SNF1-like kinase, 1, isoform CRA_a {ECO:0000313|EMBL:EAW97769.1};+++[F8VSH4_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000448288}; Flags: Fragment;+++[F8VXF0_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000449990}; Flags: Fragment;+++[F8VZ96_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000446873}; Flags: Fragment;"]
[9892,"'SNAP91'",88,72,81,80.3333333333333,{"$nulls":4},"GO:0030136///clathrin-coated vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005905///clathrin-coated pit","GO:0030276///clathrin binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0019901///protein kinase binding","GO:0048268///clathrin coat assembly+++GO:0015031///protein transport+++GO:2000369///regulation of clathrin-dependent endocytosis","synaptosome associated protein 91","[AP180_HUMAN|Reviewed]RecName: Full=Clathrin coat assembly protein AP180; AltName: Full=91 kDa synaptosomal-associated protein; AltName: Full=Clathrin coat-associated protein AP180; AltName: Full=Phosphoprotein F1-20;+++[A0A0A0MRM7_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358705}; Flags: Fragment;+++[B7Z2N2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57108, highly similar to Clathrin coat assembly protein AP180 {ECO:0000313|EMBL:BAH11918.1};+++[E5RFC6_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358704}; Flags: Fragment;+++[E5RFU0_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000427959}; Flags: Fragment;+++[E5RGP8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429950};+++[E5RGY9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430071}; Flags: Fragment;+++[E5RHK9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429700};+++[E5RIJ5_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429429}; Flags: Fragment;+++[E5RJY3_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000431055}; Flags: Fragment;+++[E5RK51_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430441}; Flags: Fragment;+++[E5RK53_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000428127};+++[E9PDG8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429776};+++[H0UI15_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein, 91kDa homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW48659.1};+++[H0YBT2_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430255}; Flags: Fragment;"]
[9894,"'TELO2'",493,446,491,476.666666666667,"04150///mTOR signaling pathway+++03460///Fanconi anemia pathway","H01789///You-Hoover-Fong syndrome",null,null,"GO:0000784///nuclear chromosome, telomeric region+++GO:0034399///nuclear periphery+++GO:0005622///intracellular+++GO:0031932///TORC2 complex+++GO:0016607///nuclear speck+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0031931///TORC1 complex+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0070209///ASTRA complex","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004713///protein tyrosine kinase activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0042162///telomeric DNA binding+++GO:0051879///Hsp90 protein binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:1904263///positive regulation of TORC1 signaling+++GO:0000723///telomere maintenance+++GO:0032526///response to retinoic acid+++GO:1904515///positive regulation of TORC2 signaling+++GO:0006468///protein phosphorylation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0032006///regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation+++GO:0010033///response to organic substance+++GO:0010212///response to ionizing radiation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0071902///positive regulation of protein serine/threonine kinase activity","telomere maintenance 2","[TELO2_HUMAN|Reviewed]RecName: Full=Telomere length regulation protein TEL2 homolog; AltName: Full=Protein clk-2 homolog; Short=hCLK2;+++[B4DXS2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58340 {ECO:0000313|EMBL:BAG63484.1};+++[H3BRS3_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000456383};+++[H3BU45_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000457461}; Flags: Fragment;+++[Q9BRG8_HUMAN|Unreviewed]SubName: Full=CLK2 protein {ECO:0000313|EMBL:AAH06274.2}; Flags: Fragment;"]
[9895,"'TECPR2'",1504,1398,1493,1465,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005515///protein binding","GO:0006914///autophagy","tectonin beta-propeller repeat containing 2","[TCPR2_HUMAN|Reviewed]RecName: Full=Tectonin beta-propeller repeat-containing protein 2; AltName: Full=WD repeat-containing protein KIAA0329/KIAA0297;+++[L8E8K7_HUMAN|Unreviewed]SubName: Full=Alternative protein TECPR2 {ECO:0000313|EMBL:CCQ43464.1};"]
[9896,"'FIG4'",385,357,381,374.333333333333,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase ATP + dCDP <=> ADP + dCTP+++R00156///ATP:UDP phosphotransferase ATP + UDP <=> ADP + UTP+++R00722///ATP:IDP phosphotransferase ATP + IDP <=> ADP + ITP+++R02093///ATP:dTDP phosphotransferase ATP + dTDP <=> ADP + dTTP+++R01547///ATP:dAMP phosphotransferase ATP + dAMP <=> ADP + dADP+++R00330///ATP:GDP phosphotransferase ATP + GDP <=> ADP + GTP+++R00570///ATP:CDP phosphotransferase ATP + CDP <=> ADP + CTP+++R00124///ATP:ADP phosphatransferase ATP + ADP <=> ADP + ATP+++R03530///ATP:dIDP phosphotransferase ATP + dIDP <=> ADP + dITP+++R00127///ATP:AMP phosphotransferase ATP + AMP <=> 2 ADP+++R01857///ATP:dGDP phosphotransferase ATP + dGDP <=> ADP + dGTP+++R02331///ATP:dUDP phosphotransferase ATP + dUDP <=> ADP + dUTP+++R01137///ATP:dADP phosphotransferase ATP + dADP <=> ADP + dATP","GO:0043231///intracellular membrane-bounded organelle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0010008///endosome membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005811///lipid droplet+++GO:0055037///recycling endosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0042578///phosphoric ester hydrolase activity+++GO:0034593///phosphatidylinositol bisphosphate phosphatase activity+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0043813///phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity","GO:0046488///phosphatidylinositol metabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0007626///locomotory behavior+++GO:0032288///myelin assembly+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0048666///neuron development+++GO:0016311///dephosphorylation+++GO:0031642///negative regulation of myelination+++GO:0007033///vacuole organization+++GO:0043473///pigmentation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process","FIG4 phosphoinositide 5-phosphatase","[FIG4_HUMAN|Reviewed]RecName: Full=Polyphosphoinositide phosphatase; EC=3.1.3.-; AltName: Full=Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; AltName: Full=SAC domain-containing protein 3;+++[H0Y6G7_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000405660}; Flags: Fragment;+++[Q5JRV4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000396566}; Flags: Fragment;+++[Q5TCS4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000357937};+++[Q5TCS5_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000412156}; Flags: Fragment;"]
[9897,"'WASHC5'",940,862,928,910,"04144///Endocytosis","H00266///Hereditary spastic paraplegia (SPG)+++H01568///3C syndrome",null,null,"GO:0005768///endosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005769///early endosome+++GO:0071203///WASH complex+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0001556///oocyte maturation+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0010976///positive regulation of neuron projection development+++GO:0090306///spindle assembly involved in meiosis+++GO:0015031///protein transport+++GO:0016197///endosomal transport","WASH complex subunit 5","[WASC5_HUMAN|Reviewed]RecName: Full=WASH complex subunit 5 {ECO:0000312|HGNC:HGNC:28984}; AltName: Full=Strumpellin; AltName: Full=WASH complex subunit strumpellin {ECO:0000305};+++[E5RFU6_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000427946}; Flags: Fragment;+++[E7EQI7_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000429676};"]
[9898,"'UBAP2L'",5447,5806,6048,5767,null,"H00100///Neutropenic disorders",null,null,"GO:0031519///PcG protein complex+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0007339///binding of sperm to zona pellucida+++GO:0061484///hematopoietic stem cell homeostasis","ubiquitin associated protein 2 like","[UBP2L_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated protein 2-like; AltName: Full=Protein NICE-4;+++[B4DYY5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55671, highly similar to Ubiquitin-associated protein 2-like {ECO:0000313|EMBL:BAG63897.1};+++[F8W726_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000271877};+++[H0Y5H6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000398609}; Flags: Fragment;+++[H7C2T8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000407672}; Flags: Fragment;+++[Q5VU77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000357490}; Flags: Fragment;+++[Q5VU78_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389052}; Flags: Fragment;+++[Q5VU79_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389717}; Flags: Fragment;+++[Q5VU80_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000415310}; Flags: Fragment;+++[Q5VU81_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000399920}; Flags: Fragment;"]
[9899,"'SV2B'",12,8,21.99,13.9966666666667,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0030672///synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction","GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0022857///transmembrane transporter activity","GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport+++GO:0006836///neurotransmitter transport","synaptic vesicle glycoprotein 2B","[SV2B_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2B;"]
[990,"'CDC6'",47,38,44,43,"04110///Cell cycle+++04111///Cell cycle - yeast+++04113///Meiosis - yeast","H01889///Meier-Gorlin syndrome",null,null,"GO:0005634///nucleus+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0051233///spindle midzone+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006270///DNA replication initiation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0051984///positive regulation of chromosome segregation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1904385///cellular response to angiotensin+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0032467///positive regulation of cytokinesis+++GO:0033314///mitotic DNA replication checkpoint+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0007089///traversing start control point of mitotic cell cycle+++GO:0000076///DNA replication checkpoint+++GO:1904117///cellular response to vasopressin+++GO:0006260///DNA replication+++GO:0051301///cell division+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000278///mitotic cell cycle","cell division cycle 6","[CDC6_HUMAN|Reviewed]RecName: Full=Cell division control protein 6 homolog; AltName: Full=CDC6-related protein; AltName: Full=Cdc18-related protein; Short=HsCdc18; AltName: Full=p62(cdc6); Short=HsCDC6;+++[A0A024R1S2_HUMAN|Unreviewed]RecName: Full=Cell division control protein {ECO:0000256|PIRNR:PIRNR001767};+++[J3KTI7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463004}; Flags: Fragment;+++[J3QLN7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463635}; Flags: Fragment;+++[J3QR52_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000464047}; Flags: Fragment;"]
[9900,"'SV2A'",404,441,389,411.333333333333,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0048786///presynaptic active zone+++GO:0045202///synapse+++GO:0098982///GABA-ergic synapse+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0098978///glutamatergic synapse+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030672///synaptic vesicle membrane+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0043005///neuron projection+++GO:0030425///dendrite","GO:0005215///transporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0014052///regulation of gamma-aminobutyric acid secretion+++GO:0006874///cellular calcium ion homeostasis+++GO:0006836///neurotransmitter transport+++GO:0007268///chemical synaptic transmission+++GO:0016082///synaptic vesicle priming","synaptic vesicle glycoprotein 2A","[SV2A_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2A;+++[B4E000_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57689, highly similar to Synaptic vesicle glycoprotein 2A {ECO:0000313|EMBL:BAG64262.1};+++[L8E840_HUMAN|Unreviewed]SubName: Full=Alternative protein SV2A {ECO:0000313|EMBL:CCQ43465.1};"]
[9901,"'SRGAP3'",205,156,257,206,"04360///Axon guidance",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005730///nucleolus","GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0016423///tRNA (guanine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0032197///transposition, RNA-mediated+++GO:0030488///tRNA methylation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","SLIT-ROBO Rho GTPase activating protein 3","[SRGP3_HUMAN|Reviewed]RecName: Full=SLIT-ROBO Rho GTPase-activating protein 3; Short=srGAP3; AltName: Full=Mental disorder-associated GAP; AltName: Full=Rho GTPase-activating protein 14; AltName: Full=WAVE-associated Rac GTPase-activating protein; Short=WRP;"]
[9902,"'MRC2'",3814,3997,2919,3576.66666666667,"04145///Phagosome+++05152///Tuberculosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005518///collagen binding","GO:0030574///collagen catabolic process+++GO:0001649///osteoblast differentiation+++GO:0006897///endocytosis","mannose receptor C type 2","[MRC2_HUMAN|Reviewed]RecName: Full=C-type mannose receptor 2; AltName: Full=C-type lectin domain family 13 member E; AltName: Full=Endocytic receptor 180; AltName: Full=Macrophage mannose receptor 2; AltName: Full=Urokinase-type plasminogen activator receptor-associated protein; Short=UPAR-associated protein; Short=Urokinase receptor-associated protein; AltName: CD_antigen=CD280; Flags: Precursor;+++[E7EME3_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000400445};+++[J3KRF1_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000461968}; Flags: Fragment;+++[J3QQZ6_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000463968}; Flags: Fragment;"]
[9903,"'KLHL21'",1547,1581,1791,1639.66666666667,{"$nulls":4},"GO:0005819///spindle+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005827///polar microtubule","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0035853///chromosome passenger complex localization to spindle midzone+++GO:0032465///regulation of cytokinesis+++GO:0016567///protein ubiquitination","kelch like family member 21","[KLH21_HUMAN|Reviewed]RecName: Full=Kelch-like protein 21;+++[K7ELI0_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466089};+++[K7EMF2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466479};+++[K7ESH2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000468710}; Flags: Fragment;+++[L8E9P8_HUMAN|Unreviewed]SubName: Full=Alternative protein KLHL21 {ECO:0000313|EMBL:CCQ43466.1};+++[Q2NKK7_HUMAN|Unreviewed]SubName: Full=KLHL21 protein {ECO:0000313|EMBL:AAI11767.1}; SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000480631};"]
[9904,"'RBM19'",558,450,510,506,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0045292///mRNA cis splicing, via spliceosome+++GO:0040019///positive regulation of embryonic development+++GO:0007275///multicellular organism development+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 19","[RBM19_HUMAN|Reviewed]RecName: Full=Probable RNA-binding protein 19; AltName: Full=RNA-binding motif protein 19;+++[A0A024RBL4_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 19, isoform CRA_a {ECO:0000313|EMBL:EAW98063.1};+++[H0YIL2_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein 19 {ECO:0000313|Ensembl:ENSP00000449604}; Flags: Fragment;"]
[9905,"'SGSM2'",2421,2483,2416,2440,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0042470///melanosome","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:0034499///late endosome to Golgi transport+++GO:0090630///activation of GTPase activity+++GO:0043547///positive regulation of GTPase activity","small G protein signaling modulator 2","[SGSM2_HUMAN|Reviewed]RecName: Full=Small G protein signaling modulator 2; AltName: Full=RUN and TBC1 domain-containing protein 1;+++[B9A6J3_HUMAN|Unreviewed]SubName: Full=RUN and TBC1 domain-containing protein 1 {ECO:0000313|EMBL:BAH16621.1};+++[I3L1Y7_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000459218};+++[I3L361_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000460205}; Flags: Fragment;+++[I3NI18_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000461820}; Flags: Fragment;+++[J3QSA2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000464593}; Flags: Fragment;+++[V9GYD2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476637}; Flags: Fragment;+++[V9GYJ0_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476800};"]
[9906,"'SLC35E2A'",677.66,557.57,663.4,632.876666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0006468///protein phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0006915///apoptotic process+++GO:0050684///regulation of mRNA processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0001558///regulation of cell growth","solute carrier family 35 member E2A","[S35E2_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member E2;"]
[9907,"'AP5Z1'",875.01,855,927.02,885.676666666667,null,"H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005634///nucleus+++GO:0044599///AP-5 adaptor complex+++GO:0005737///cytoplasm+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006974///cellular response to DNA damage stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0015031///protein transport+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0016197///endosomal transport","adaptor related protein complex 5 subunit zeta 1","[AP5Z1_HUMAN|Reviewed]RecName: Full=AP-5 complex subunit zeta-1; AltName: Full=Adaptor-related protein complex 5 zeta subunit; Short=Zeta5;+++[A0A024R817_HUMAN|Unreviewed]SubName: Full=KIAA0415 protein, isoform CRA_d {ECO:0000313|EMBL:EAW87298.1};+++[A4D1Z4_HUMAN|Unreviewed]SubName: Full=KIAA0415 gene product {ECO:0000313|EMBL:EAL23965.1};"]
[9908,"'G3BP2'",2149,1567,1727,1814.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003676///nucleic acid binding+++GO:0030159///receptor signaling complex scaffold activity","GO:0034063///stress granule assembly+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0051028///mRNA transport+++GO:0007265///Ras protein signal transduction","G3BP stress granule assembly factor 2","[G3BP2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 2; Short=G3BP-2; AltName: Full=GAP SH3 domain-binding protein 2;+++[A0A024RDB2_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX05747.1};+++[A0A024RDE5_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAX05746.1};+++[D6R9A4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423245}; Flags: Fragment;+++[D6R9X5_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422830}; Flags: Fragment;+++[D6RAC7_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422748}; Flags: Fragment;+++[D6RB17_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424522}; Flags: Fragment;+++[D6RBM9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424060}; Flags: Fragment;+++[D6RBR0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422614}; Flags: Fragment;+++[D6RBW8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423960}; Flags: Fragment;+++[D6RE13_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000425122}; Flags: Fragment;+++[D6REX8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000421621}; Flags: Fragment;+++[D6RGJ4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426311}; Flags: Fragment;+++[H0YAE3_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426843}; Flags: Fragment;"]
[9909,"'DENND4B'",647,628,585,620,{"$nulls":4},"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032483///regulation of Rab protein signal transduction","DENN domain containing 4B","[DEN4B_HUMAN|Reviewed]RecName: Full=DENN domain-containing protein 4B;+++[E9PAK5_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000357635}; Flags: Fragment;+++[H0YEF0_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000435709}; Flags: Fragment;"]
[991,"'CDC20'",20,13,23,18.6666666666667,"04110///Cell cycle+++04111///Cell cycle - yeast+++05203///Viral carcinogenesis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis+++04114///Oocyte meiosis",null,"M00389///APC/C complex",null,"GO:0005680///anaphase-promoting complex+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005819///spindle+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0010997///anaphase-promoting complex binding+++GO:0005515///protein binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:0042826///histone deacetylase binding+++GO:0019899///enzyme binding+++GO:0008022///protein C-terminus binding","GO:0016579///protein deubiquitination+++GO:0050773///regulation of dendrite development+++GO:0051301///cell division+++GO:0090307///mitotic spindle assembly+++GO:0090129///positive regulation of synapse maturation+++GO:0040020///regulation of meiotic nuclear division+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0007399///nervous system development+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0007049///cell cycle+++GO:0031915///positive regulation of synaptic plasticity+++GO:0007094///mitotic spindle assembly checkpoint+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0030154///cell differentiation+++GO:0016567///protein ubiquitination+++GO:0007064///mitotic sister chromatid cohesion+++GO:0008284///positive regulation of cell proliferation","cell division cycle 20","[CDC20_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 20 homolog; AltName: Full=p55CDC;"]
[9910,"'RABGAP1L'",819.46,607,776,734.153333333333,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005929///cilium+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:1902017///regulation of cilium assembly+++GO:0090630///activation of GTPase activity+++GO:0032880///regulation of protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0006897///endocytosis+++GO:0015031///protein transport","RAB GTPase activating protein 1 like","[RBG10_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like, isoform 10;+++[RBG1L_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like;+++[A0A0C4DG54_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000403136}; Flags: Fragment;+++[A0A0U1RQT5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489163}; Flags: Fragment;+++[A0A0U1RQV7_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489188}; Flags: Fragment;+++[A0A0U1RQX4_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489213}; Flags: Fragment;+++[A0A0U1RQY6_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489232};+++[A0A0U1RRM5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489605};+++[E9PNV2_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000432734};+++[E9PS63_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000435911}; Flags: Fragment;+++[F1LJ00_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 18 {ECO:0000313|EMBL:BAH16647.1};+++[F5H8L0_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000375916};+++[Q9Y3L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAB41265.1}; Flags: Fragment;"]
[9911,"'TMCC2'",565,563,723,617,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0042982///amyloid precursor protein metabolic process","transmembrane and coiled-coil domain family 2","[TMCC2_HUMAN|Reviewed]RecName: Full=Transmembrane and coiled-coil domains protein 2; AltName: Full=Cerebral protein 11;+++[A0A0C4DFR1_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000331842};+++[A0A1B0GUZ3_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_a {ECO:0000313|EMBL:EAW91545.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000490308};+++[G5E963_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_b {ECO:0000313|EMBL:EAW91546.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000329436};+++[Q8IW47_HUMAN|Unreviewed]SubName: Full=TMCC2 protein {ECO:0000313|EMBL:AAH41019.1}; Flags: Fragment;"]
[9912,"'ARHGAP44'",150,136,160,148.666666666667,"03013///RNA transport+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0042995///cell projection+++GO:0055037///recycling endosome+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine+++GO:0005829///cytosol+++GO:0031256///leading edge membrane+++GO:0030054///cell junction+++GO:0048786///presynaptic active zone+++GO:0005768///endosome","GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding","GO:0043547///positive regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0007165///signal transduction+++GO:0098886///modification of dendritic spine+++GO:0099010///modification of postsynaptic structure+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0006887///exocytosis+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099152///regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 44","[RHG44_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 44; AltName: Full=NPC-A-10; AltName: Full=Rho-type GTPase-activating protein RICH2; AltName: Full=RhoGAP interacting with CIP4 homologs protein 2; Short=RICH-2;+++[A0A087WZS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000482851};+++[A0A2X0U4K4_HUMAN|Unreviewed]SubName: Full=ARHGAP44 {ECO:0000313|EMBL:SPT35710.1}; Flags: Fragment;+++[E7ERK8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000262444};+++[F5H6L3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000437542};+++[J3KRS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000462141};+++[J3QQU7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000463905}; Flags: Fragment;+++[K7EK86_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000465509}; Flags: Fragment;+++[Q69Z00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp564G2272 {ECO:0000313|EMBL:CAH10728.1}; Flags: Fragment;+++[Q8TBK1_HUMAN|Unreviewed]SubName: Full=RICH2 protein {ECO:0000313|EMBL:AAH22452.3}; Flags: Fragment;"]
[9913,"'SUPT7L'",754.9,653,725,710.966666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex","GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0046982///protein heterodimerization activity","GO:0043966///histone H3 acetylation+++GO:0051457///maintenance of protein location in nucleus+++GO:1903508///positive regulation of nucleic acid-templated transcription","SPT7 like, STAGA complex gamma subunit","[ST65G_HUMAN|Reviewed]RecName: Full=STAGA complex 65 subunit gamma; AltName: Full=Adenocarcinoma antigen ART1; AltName: Full=SPTF-associated factor 65 gamma; Short=STAF65gamma; AltName: Full=Suppressor of Ty 7-like;"]
[9914,"'ATP2C2'",5,3,8,5.33333333333333,null,"H00844///Familial benign chronic pemphigus",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005388///calcium-transporting ATPase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0015410///manganese-transporting ATPase activity+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0090280///positive regulation of calcium ion import+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0006874///cellular calcium ion homeostasis+++GO:0070588///calcium ion transmembrane transport+++GO:0006816///calcium ion transport+++GO:0006811///ion transport+++GO:1902600///proton transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0061180///mammary gland epithelium development","ATPase secretory pathway Ca2+ transporting 2","[AT2C2_HUMAN|Reviewed]RecName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000305}; Short=ATPase 2C2; EC=3.6.3.8; AltName: Full=Secretory pathway Ca(2+)-ATPase 2;+++[A0A0A0MSP0_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[B3KR57_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[H3BS90_HUMAN|Unreviewed]SubName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000313|Ensembl:ENSP00000456595}; Flags: Fragment;"]
[9915,"'ARNT2'",1523,1129,1850,1500.66666666667,"05200///Pathways in cancer+++05211///Renal cell carcinoma+++05202///Transcriptional misregulation in cancer","H01797///Webb-Dattani syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0032355///response to estradiol+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006805///xenobiotic metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II","aryl hydrocarbon receptor nuclear translocator 2","[ARNT2_HUMAN|Reviewed]RecName: Full=Aryl hydrocarbon receptor nuclear translocator 2; Short=ARNT protein 2; AltName: Full=Class E basic helix-loop-helix protein 1; Short=bHLHe1;+++[A0A087WVE9_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000479393};+++[H0YKW1_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000452961}; Flags: Fragment;+++[Q7Z3A3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686M216 {ECO:0000313|EMBL:CAD97972.1};+++[Q86TN1_HUMAN|Unreviewed]SubName: Full=ARNT2 protein {ECO:0000313|EMBL:AAH51335.1};+++[X5D7T2_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56635.1};+++[X5D8U0_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform G {ECO:0000313|EMBL:AHW56413.1}; Flags: Fragment;+++[X5D9H9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform B {ECO:0000313|EMBL:AHW56648.1};+++[X5DP31_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform E {ECO:0000313|EMBL:AHW56626.1};+++[X5DP40_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56636.1};+++[X5DP87_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform F {ECO:0000313|EMBL:AHW56696.1};+++[X5DQN9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform D {ECO:0000313|EMBL:AHW56412.1}; Flags: Fragment;+++[X5DRE4_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform H {ECO:0000313|EMBL:AHW56647.1};"]
[9917,"'FAM20B'",554,500,482,512,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","FAM20B, glycosaminoglycan xylosylkinase","[XYLK_HUMAN|Reviewed]RecName: Full=Glycosaminoglycan xylosylkinase; EC=2.7.1.- {ECO:0000269|PubMed:19473117}; AltName: Full=Xylose kinase;+++[A0A024R918_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 20, member B, isoform CRA_a {ECO:0000313|EMBL:EAW91036.1};+++[X6RH03_HUMAN|Unreviewed]SubName: Full=Glycosaminoglycan xylosylkinase {ECO:0000313|Ensembl:ENSP00000404005}; Flags: Fragment;"]
[9918,"'NCAPD2'",759,707,665,710.333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0000799///nuclear condensin complex+++GO:0000228///nuclear chromosome+++GO:0000793///condensed chromosome+++GO:0016020///membrane+++GO:0000797///condensin core heterodimer+++GO:0005829///cytosol+++GO:0000779///condensed chromosome, centromeric region+++GO:0005737///cytoplasm","GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding","GO:0051304///chromosome separation+++GO:0010032///meiotic chromosome condensation+++GO:0007049///cell cycle+++GO:0030261///chromosome condensation+++GO:0007076///mitotic chromosome condensation+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","non-SMC condensin I complex subunit D2","[CND1_HUMAN|Reviewed]RecName: Full=Condensin complex subunit 1; AltName: Full=Chromosome condensation-related SMC-associated protein 1; AltName: Full=Chromosome-associated protein D2; Short=hCAP-D2; AltName: Full=Non-SMC condensin I complex subunit D2; AltName: Full=XCAP-D2 homolog;+++[A0PJ76_HUMAN|Unreviewed]SubName: Full=NCAPD2 protein {ECO:0000313|EMBL:AAH16913.1}; Flags: Fragment;+++[B3KMS0_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[B3KY03_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[E7EN77_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000371895}; Flags: Fragment;+++[F5GZK7_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000444377}; Flags: Fragment;+++[F5H431_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000438495};"]
[9919,"'SEC16A'",4611,3841,4108,4186.66666666667,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0031090///organelle membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding","GO:0007030///Golgi organization+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0043000///Golgi to plasma membrane CFTR protein transport+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0007029///endoplasmic reticulum organization+++GO:0050821///protein stabilization+++GO:0034976///response to endoplasmic reticulum stress+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0021762///substantia nigra development+++GO:0072659///protein localization to plasma membrane+++GO:0016192///vesicle-mediated transport+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0006888///ER to Golgi vesicle-mediated transport","SEC16 homolog A, endoplasmic reticulum export factor","[SC16A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec16A; AltName: Full=SEC16 homolog A;+++[A0A0C4DH09_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000277537}; Flags: Fragment;+++[A0PJ75_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH16873.1}; Flags: Fragment;+++[A4QN18_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[A4QN19_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[F1T0I1_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[G1UI25_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|EMBL:BAK64148.1}; Flags: Fragment;+++[J3KNL6_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[Q8N9G1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000317437}; SubName: Full=cDNA FLJ37437 fis, clone BRAWH2003025 {ECO:0000313|EMBL:BAC04415.1};+++[Q9BV84_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH01404.2}; Flags: Fragment;+++[X6RGP5_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;"]
[9920,"'KBTBD11'",844,592,690,708.666666666667,{"$nulls":4},"GO:0031463///Cul3-RING ubiquitin ligase complex",null,"GO:0016567///protein ubiquitination","kelch repeat and BTB domain containing 11","[KBTBB_HUMAN|Reviewed]RecName: Full=Kelch repeat and BTB domain-containing protein 11; AltName: Full=Chronic myelogenous leukemia-associated protein; AltName: Full=Kelch domain-containing protein 7B;"]
[9921,"'RNF10'",2669,2435,2521,2541.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding","GO:0051865///protein autoubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031643///positive regulation of myelination+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated","ring finger protein 10","[RNF10_HUMAN|Reviewed]RecName: Full=RING finger protein 10;+++[A0A024RBP0_HUMAN|Unreviewed]SubName: Full=Ring finger protein 10, isoform CRA_a {ECO:0000313|EMBL:EAW98203.1};+++[A0A0G2JKT9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000438638}; Flags: Fragment;+++[F5H3A4_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439221}; Flags: Fragment;+++[F5H510_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000444770}; Flags: Fragment;+++[F5H5P6_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443235}; Flags: Fragment;+++[F5H5Z1_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443000};+++[H0YF69_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000437392}; Flags: Fragment;+++[H0YFN9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439510}; Flags: Fragment;+++[H0YFQ9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439859}; Flags: Fragment;+++[H0YG28_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000441487}; Flags: Fragment;+++[H0YGL7_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443790}; Flags: Fragment;+++[H0YGX5_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000445160}; Flags: Fragment;"]
[9922,"'IQSEC1'",2798,2392,3008,2732.66666666667,"04144///Endocytosis","H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032012///regulation of ARF protein signal transduction+++GO:0051549///positive regulation of keratinocyte migration+++GO:0043547///positive regulation of GTPase activity+++GO:1903393///positive regulation of adherens junction organization+++GO:0030036///actin cytoskeleton organization","IQ motif and Sec7 domain 1","[IQEC1_HUMAN|Reviewed]RecName: Full=IQ motif and SEC7 domain-containing protein 1; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 100; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 2; AltName: Full=Brefeldin-resistant Arf-GEF 2 protein {ECO:0000303|PubMed:16461286}; Short=BRAG2 {ECO:0000303|PubMed:24058294};+++[A0A087WWK8_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000480301};+++[A0A0C4DGT3_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000478001};+++[A0A2R8Y695_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000495163}; Flags: Fragment;+++[A0A2R8Y7T6_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496366};+++[B4DGC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60491, highly similar to IQ motif and Sec7 domain-containing protein 1 {ECO:0000313|EMBL:BAG57736.1};+++[L0R4Y9_HUMAN|Unreviewed]SubName: Full=Alternative protein IQSEC1 {ECO:0000313|EMBL:CCO13748.1};"]
[9923,"'ZBTB40'",558,363,439,453.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0030282///bone mineralization+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 40","[ZBT40_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 40;+++[B1AKC8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000383098}; Flags: Fragment;+++[B2RBP0_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 40, isoform CRA_a {ECO:0000313|EMBL:EAW95011.1}; SubName: Full=cDNA, FLJ95610, Homo sapiens KIAA0478 gene product (KIAA0478), mRNA {ECO:0000313|EMBL:BAG37287.1};+++[B3KR52_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33700 fis, clone BRAWH2005074, highly similar to Zinc finger and BTB domain-containing protein 40 {ECO:0000313|EMBL:BAG52264.1}; Flags: Fragment;+++[F8WAI8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000363782};+++[Q1RMZ5_HUMAN|Unreviewed]SubName: Full=ZBTB40 protein {ECO:0000313|EMBL:AAI14608.1};"]
[9924,"'PAN2'",271,195,343,269.666666666667,"03018///RNA degradation",null,"M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00010///Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate+++M00740///Methylaspartate cycle+++M00012///Glyoxylate cycle","R00351///acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing) Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate","GO:0000932///P-body+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0031251///PAN complex+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0004108///citrate (Si)-synthase activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0000175///3'-5'-exoribonuclease activity","GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0006397///mRNA processing+++GO:0005975///carbohydrate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening","poly(A) specific ribonuclease subunit PAN2","[PAN2_HUMAN|Reviewed]RecName: Full=PAN2-PAN3 deadenylation complex catalytic subunit PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}; EC=3.1.13.4 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 52 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=PAB1P-dependent poly(A)-specific ribonuclease {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Poly(A)-nuclease deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182}; Short=PAN deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182};"]
[9925,"'ZBTB5'",370,348,316,344.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus","zinc finger and BTB domain containing 5","[ZBTB5_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 5;+++[Q5T942_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 5 {ECO:0000313|EMBL:EAW58282.1}; SubName: Full=cDNA FLJ77230, highly similar to Homo sapiens zinc finger and BTB domain containing 5 (ZBTB5), mRNA {ECO:0000313|EMBL:BAF85093.1};"]
[9926,"'LPGAT1'",362.05,246,396,334.683333333333,"00564///Glycerophospholipid metabolism",null,null,"R09036///acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0003674///molecular_function","GO:0006629///lipid metabolic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","lysophosphatidylglycerol acyltransferase 1","[LGAT1_HUMAN|Reviewed]RecName: Full=Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; EC=2.3.1.-;"]
[9927,"'MFN2'",1631,1619,1688,1646,"04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway+++04214///Apoptosis - fly","H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0031306///intrinsic component of mitochondrial outer membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton","GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0001825///blastocyst formation+++GO:0007050///cell cycle arrest+++GO:0006986///response to unfolded protein+++GO:0007596///blood coagulation+++GO:0051646///mitochondrion localization+++GO:0006914///autophagy+++GO:0048593///camera-type eye morphogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:0016236///macroautophagy+++GO:0006626///protein targeting to mitochondrion+++GO:0008053///mitochondrial fusion+++GO:0006915///apoptotic process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0034497///protein localization to phagophore assembly site+++GO:0007006///mitochondrial membrane organization","mitofusin 2","[MFN2_HUMAN|Reviewed]RecName: Full=Mitofusin-2; EC=3.6.5.-; AltName: Full=Transmembrane GTPase MFN2;+++[Q5JXC5_HUMAN|Unreviewed]SubName: Full=Mitofusin-2 {ECO:0000313|Ensembl:ENSP00000412023}; Flags: Fragment;"]
[9928,"'KIF14'",5.96,1,3,3.32,null,"H01513///Retinoblastoma+++H00261///Meckel syndrome (MKS)",null,null,"GO:0005874///microtubule+++GO:0005819///spindle+++GO:0030496///midbody+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0051233///spindle midzone+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0015631///tubulin binding+++GO:0030165///PDZ domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed","GO:0021695///cerebellar cortex development+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0032467///positive regulation of cytokinesis+++GO:0051301///cell division+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0032147///activation of protein kinase activity+++GO:0021846///cell proliferation in forebrain+++GO:0033624///negative regulation of integrin activation+++GO:0021693///cerebellar Purkinje cell layer structural organization+++GO:0021772///olfactory bulb development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0030155///regulation of cell adhesion+++GO:0007080///mitotic metaphase plate congression+++GO:0021766///hippocampus development+++GO:0032487///regulation of Rap protein signal transduction+++GO:0043523///regulation of neuron apoptotic process+++GO:0007019///microtubule depolymerization+++GO:0045184///establishment of protein localization+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0021685///cerebellar granular layer structural organization+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0008284///positive regulation of cell proliferation+++GO:0031641///regulation of myelination+++GO:0007018///microtubule-based movement+++GO:0030334///regulation of cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0021987///cerebral cortex development+++GO:1903429///regulation of cell maturation+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process","kinesin family member 14","[KIF14_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF14 {ECO:0000305};"]
[9929,"'JOSD1'",774,687.94,715,725.646666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","Josephin domain containing 1","[JOS1_HUMAN|Reviewed]RecName: Full=Josephin-1; EC=3.4.19.12; AltName: Full=Josephin domain-containing protein 1;+++[A0A024R1P5_HUMAN|Unreviewed]SubName: Full=Josephin domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW60260.1};+++[B0QY55_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000393131}; Flags: Fragment;+++[B0QY56_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000410010}; Flags: Fragment;+++[B0QY57_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000415189}; Flags: Fragment;+++[B0QY58_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000405182}; Flags: Fragment;+++[H0YGT9_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000444798}; Flags: Fragment;"]
[993,"'CDC25A'",25,22,15,20.6666666666667,"05206///MicroRNAs in cancer+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04218///Cellular senescence",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0051087///chaperone binding","GO:0007049///cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016579///protein deubiquitination+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0009314///response to radiation+++GO:0034644///cellular response to UV","cell division cycle 25A","[MPIP1_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 1; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25A;+++[A0A024R2R6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_b {ECO:0000313|EMBL:EAW64852.1};+++[A0A024R2S4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_a {ECO:0000313|EMBL:EAW64851.1};+++[C9JFR5_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000416483}; Flags: Fragment;+++[C9JH94_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000404285}; Flags: Fragment;+++[D8KXX0_HUMAN|Unreviewed]SubName: Full=CDC25A2-CAG isoform {ECO:0000313|EMBL:ACI43572.1};+++[K7N7S0_HUMAN|Unreviewed]SubName: Full=CDC25 isoform A1-CAG {ECO:0000313|EMBL:ACZ05628.1};"]
[9931,"'HELZ'",787,574,626,662.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043186///P granule+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding","GO:0035194///posttranscriptional gene silencing by RNA","helicase with zinc finger","[HELZ_HUMAN|Reviewed]RecName: Full=Probable helicase with zinc finger domain; EC=3.6.4.-; AltName: Full=Down-regulated in human cancers protein;+++[A0A024R8K8_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger, isoform CRA_a {ECO:0000313|EMBL:EAW89024.1};+++[A0A075B6R3_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000411144};+++[A0A2P0H7U5_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger {ECO:0000313|EMBL:AAI30583.1};+++[B7ZLW2_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAI44084.1};+++[C1KEM4_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49579.1}; Flags: Fragment;+++[C1KEM5_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49580.1}; Flags: Fragment;+++[J3KS59_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462320}; Flags: Fragment;+++[J3KT20_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462763}; Flags: Fragment;+++[J3QRR8_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464354}; Flags: Fragment;+++[J3QS41_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464512};+++[Q6PGP6_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAH56895.1}; Flags: Fragment;"]
[9933,"'PUM3'",412,324,334,356.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0010835///regulation of protein ADP-ribosylation","pumilio RNA binding family member 3","[PUM3_HUMAN|Reviewed]RecName: Full=Pumilio homolog 3 {ECO:0000305}; AltName: Full=HBV X-transactivated gene 5 protein; AltName: Full=HBV XAg-transactivated protein 5; AltName: Full=Minor histocompatibility antigen HA-8; Short=HLA-HA8;+++[Q9NYH5_HUMAN|Unreviewed]SubName: Full=KIAA0020 protein {ECO:0000313|EMBL:AAF69838.1}; Flags: Fragment;+++[S4R3K8_HUMAN|Unreviewed]SubName: Full=Pumilio homolog 3 {ECO:0000313|Ensembl:ENSP00000474467}; Flags: Fragment;"]
[9935,"'MAFB'",70,41,47,52.6666666666667,"04928///Parathyroid hormone synthesis, secretion and action","H01865///Multicentric carpotarsal osteolysis syndrome",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0007379///segment specification+++GO:0007585///respiratory gaseous exchange+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042472///inner ear morphogenesis+++GO:0021571///rhombomere 5 development+++GO:0021572///rhombomere 6 development+++GO:0007423///sensory organ development+++GO:0033077///T cell differentiation in thymus+++GO:0035284///brain segmentation+++GO:0021599///abducens nerve formation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0048538///thymus development","MAF bZIP transcription factor B","[MAFB_HUMAN|Reviewed]RecName: Full=Transcription factor MafB; Short=Maf-B; AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog B;+++[L8ECC4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAFB {ECO:0000313|EMBL:CCQ43322.1};"]
[9936,"'CD302'",155.52,108,132.62,132.046666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005902///microvillus+++GO:0030175///filopodium+++GO:0005938///cell cortex+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0006909///phagocytosis","CD302 molecule","[CD302_HUMAN|Reviewed]RecName: Full=CD302 antigen; AltName: Full=C-type lectin BIMLEC; AltName: Full=C-type lectin domain family 13 member A; AltName: Full=DEC205-associated C-type lectin 1; AltName: Full=Type I transmembrane C-type lectin receptor DCL-1; AltName: CD_antigen=CD302; Flags: Precursor;+++[A0A087WT00_HUMAN|Unreviewed]SubName: Full=CD302 antigen {ECO:0000313|Ensembl:ENSP00000451446};"]
[9937,"'DCLRE1A'",107,65,98,90,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0003684///damaged DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0051301///cell division+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0007049///cell cycle","DNA cross-link repair 1A","[DCR1A_HUMAN|Reviewed]RecName: Full=DNA cross-link repair 1A protein; AltName: Full=SNM1 homolog A; Short=hSNM1; Short=hSNM1A;"]
[9938,"'ARHGAP25'",5,6,5,5.33333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0001891///phagocytic cup","GO:0005096///GTPase activator activity","GO:0006911///phagocytosis, engulfment+++GO:0007165///signal transduction+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007015///actin filament organization+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 25","[RHG25_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 25; AltName: Full=Rho-type GTPase-activating protein 25;+++[A0A2X0TVS2_HUMAN|Unreviewed]SubName: Full=ARHGAP25 {ECO:0000313|EMBL:SPT35696.1}; Flags: Fragment;+++[B7Z8K7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417283}; SubName: Full=cDNA FLJ59112, highly similar to Rho-GTPase-activating protein 25 {ECO:0000313|EMBL:BAH13993.1};+++[C9JB56_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417467};+++[F8WAV9_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417425};+++[F8WDF6_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000420427};+++[H7C4P1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417818}; Flags: Fragment;+++[V9HWC8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 308 {ECO:0000313|EMBL:ACJ13710.1}; SubName: Full=Rho GTPase activating protein 25, isoform CRA_b {ECO:0000313|EMBL:EAW99867.1};"]
[9939,"'RBM8A'",1260,1195,1150,1201.66666666667,"03015///mRNA surveillance pathway+++03040///Spliceosome+++03013///RNA transport","H01847///Thrombocytopenia-absent radius syndrome","M00430///Exon junction complex (EJC)",null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0071013///catalytic step 2 spliceosome+++GO:0035145///exon-exon junction complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding","GO:0031124///mRNA 3'-end processing+++GO:0006417///regulation of translation+++GO:0006396///RNA processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0051028///mRNA transport+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006406///mRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 8A","[RBM8A_HUMAN|Reviewed]RecName: Full=RNA-binding protein 8A; AltName: Full=Binder of OVCA1-1; Short=BOV-1; AltName: Full=RNA-binding motif protein 8A; AltName: Full=RNA-binding protein Y14; AltName: Full=Ribonucleoprotein RBM8A;+++[A0A023T787_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239};+++[A0A060D9J6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 8A {ECO:0000313|EMBL:AIB06359.1}; Flags: Fragment;+++[A0A0J9YW13_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239}; Flags: Fragment;+++[L8E9A7_HUMAN|Unreviewed]SubName: Full=Alternative protein RBM8A {ECO:0000313|EMBL:CCQ43301.1};"]
[994,"'CDC25B'",241,280,262,261,"04110///Cell cycle+++05206///MicroRNAs in cancer+++04010///MAPK signaling pathway+++04914///Progesterone-mediated oocyte maturation",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0001556///oocyte maturation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0007144///female meiosis I+++GO:0007049///cell cycle+++GO:0000278///mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0006468///protein phosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0051301///cell division+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0032467///positive regulation of cytokinesis","cell division cycle 25B","[MPIP2_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 2; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25B;+++[B3KS38_HUMAN|Unreviewed]SubName: Full=HCG39252, isoform CRA_g {ECO:0000313|EMBL:EAX10500.1}; SubName: Full=Isoform CDC25B6 {ECO:0000313|EMBL:CBX26628.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26628.1}; SubName: Full=cDNA FLJ35394 fis, clone SKNSH2002768, highly similar to M-PHASE INDUCER PHOSPHATASE 2 {ECO:0000313|EMBL:BAG52600.1};+++[B4DIG0_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000339125}; SubName: Full=cDNA FLJ53333, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG58472.1};+++[B4DQZ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55479, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61105.1};+++[B4DRC3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56140, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61235.1};+++[E1YMX4_HUMAN|Unreviewed]SubName: Full=Isoform CDC25B7 {ECO:0000313|EMBL:CBX26629.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26629.1};+++[G8JLH2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000368918};+++[L8E819_HUMAN|Unreviewed]SubName: Full=Alternative protein CDC25B {ECO:0000313|EMBL:CCQ43259.1};+++[O43550_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94625.1}; Flags: Fragment;+++[Q6MZW8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G14213 {ECO:0000313|EMBL:CAE45909.2}; Flags: Fragment;+++[Q7LDQ7_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94623.1}; Flags: Fragment;"]
[9940,"'DLEC1'",6,1,12,6.33333333333333,"00592///alpha-Linolenic acid metabolism+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++04146///Peroxisome+++00280///Valine, leucine and isoleucine degradation+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03320///PPAR signaling pathway+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism",null,"M00087///beta-Oxidation+++M00113///Jasmonic acid biosynthesis","R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R07953///(4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapenta-6,9,12,15,18-enoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R07891///OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R07937///(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexa-6,9,12,15,18,21-enoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA+++R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R07899///(+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA+++R07895///OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA","GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0005925///focal adhesion+++GO:0005901///caveola","GO:0003674///molecular_function+++GO:0005096///GTPase activator activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding","GO:0030900///forebrain development+++GO:0008285///negative regulation of cell proliferation+++GO:0021575///hindbrain morphogenesis+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:0008360///regulation of cell shape+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007165///signal transduction+++GO:0003007///heart morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0006915///apoptotic process+++GO:0051497///negative regulation of stress fiber assembly+++GO:0048041///focal adhesion assembly+++GO:0001843///neural tube closure+++GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity","DLEC1, cilia and flagella associated protein","[DLEC1_HUMAN|Reviewed]RecName: Full=Deleted in lung and esophageal cancer protein 1; AltName: Full=Deleted in lung cancer protein 1; Short=DLC-1;+++[A1L305_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29825.1};+++[A2VDF1_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29826.1}; Flags: Fragment;+++[B1B5Y4_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|EMBL:BAG11659.1}; Flags: Fragment;+++[B7ZW06_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 {ECO:0000313|EMBL:AAI71799.1};+++[Q32W76_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 3 {ECO:0000313|EMBL:AAX18635.1}; SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|Ensembl:ENSP00000404261}; Flags: Fragment;+++[Q32W77_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript varient 2 {ECO:0000313|EMBL:AAX18634.1}; Flags: Fragment;+++[Q32W78_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 1 {ECO:0000313|EMBL:AAX18633.1}; Flags: Fragment;"]
[9941,"'EXOG'",112,74,100,95.3333333333333,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004529///exodeoxyribonuclease activity+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0008409///5'-3' exonuclease activity","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006309///apoptotic DNA fragmentation+++GO:0008150///biological_process","exo/endonuclease G","[EXOG_HUMAN|Reviewed]RecName: Full=Nuclease EXOG, mitochondrial; EC=3.1.30.-; AltName: Full=Endonuclease G-like 1; Short=Endo G-like 1; Flags: Precursor;+++[A0A024R2T8_HUMAN|Unreviewed]SubName: Full=Endonuclease G-like 1, isoform CRA_b {ECO:0000313|EMBL:EAW64539.1};+++[F2Z2D3_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000400239};+++[F8WC11_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000412756};+++[F8WE28_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000394977};+++[F8WE38_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000402164};+++[F8WEP0_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000413176};+++[H0Y8P1_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000421649}; Flags: Fragment;+++[H7C0W6_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000397124}; Flags: Fragment;+++[H7C451_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000415568}; Flags: Fragment;"]
[9942,"'XYLB'",148,120.11,261.08,176.396666666667,"00040///Pentose and glucuronate interconversions+++01100///Metabolic pathways","H00632///Heterotaxy","M00014///Glucuronate pathway (uronate pathway)","R01639///ATP:D-xylulose 5-phosphotransferase   ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0004856///xylulokinase activity","GO:0005975///carbohydrate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0005997///xylulose metabolic process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0016310///phosphorylation+++GO:0005998///xylulose catabolic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0042732///D-xylose metabolic process","xylulokinase","[XYLB_HUMAN|Reviewed]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;+++[C9J0N9_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000412282};+++[F8WBF6_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000398845};+++[Q6PIS3_HUMAN|Unreviewed]SubName: Full=XYLB protein {ECO:0000313|EMBL:AAH30231.1}; Flags: Fragment;"]
[9943,"'OXSR1'",830,682,658,723.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0042802///identical protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity","GO:0072143///mesangial cell development+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0002062///chondrocyte differentiation+++GO:1990869///cellular response to chemokine+++GO:0072207///metanephric epithelium development+++GO:0023014///signal transduction by protein phosphorylation+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:0001657///ureteric bud development+++GO:0072169///specification of posterior mesonephric tubule identity+++GO:0072168///specification of anterior mesonephric tubule identity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0072111///cell proliferation involved in kidney development+++GO:0072166///posterior mesonephric tubule development+++GO:0006979///response to oxidative stress+++GO:0001655///urogenital system development+++GO:0032147///activation of protein kinase activity+++GO:0048863///stem cell differentiation+++GO:0048793///pronephros development+++GO:0072234///metanephric nephron tubule development+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0042733///embryonic digit morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0023016///signal transduction by trans-phosphorylation+++GO:0001823///mesonephros development+++GO:0071476///cellular hypotonic response+++GO:2000543///positive regulation of gastrulation+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0038146///chemokine (C-X-C motif) ligand 12 signaling pathway+++GO:0071300///cellular response to retinoic acid+++GO:0060021///roof of mouth development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0072180///mesonephric duct morphogenesis+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:0072190///ureter urothelium development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0042474///middle ear morphogenesis+++GO:0072184///renal vesicle progenitor cell differentiation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0016310///phosphorylation+++GO:0072259///metanephric interstitial fibroblast development+++GO:0007231///osmosensory signaling pathway+++GO:0030154///cell differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072268///pattern specification involved in metanephros development+++GO:0042476///odontogenesis+++GO:0072183///negative regulation of nephron tubule epithelial cell differentiation+++GO:0008406///gonad development+++GO:0072075///metanephric mesenchyme development+++GO:0072498///embryonic skeletal joint development+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0072208///metanephric smooth muscle tissue development+++GO:0043066///negative regulation of apoptotic process+++GO:0030501///positive regulation of bone mineralization+++GO:0001656///metanephros development+++GO:0035556///intracellular signal transduction+++GO:0090094///metanephric cap mesenchymal cell proliferation involved in metanephros development+++GO:0046777///protein autophosphorylation+++GO:0048389///intermediate mesoderm development","oxidative stress responsive 1","[OXSR1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase OSR1; EC=2.7.11.1; AltName: Full=Oxidative stress-responsive 1 protein;+++[A0A024R2M7_HUMAN|Unreviewed]SubName: Full=Oxidative-stress responsive 1, isoform CRA_a {ECO:0000313|EMBL:EAW64523.1};+++[C9JIG9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000415851};+++[F8WBK9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000398356};+++[L8ECC0_HUMAN|Unreviewed]SubName: Full=Alternative protein OXSR1 {ECO:0000313|EMBL:CCQ43302.1};"]
[9945,"'GFPT2'",61,65,94,73.3333333333333,"01130///Biosynthesis of antibiotics+++00250///Alanine, aspartate and glutamate metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++04931///Insulin resistance+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome",null,"R00768///L-glutamine:D-fructose-6-phosphate isomerase (deaminating); L-glutamine:D-fructose-6-phosphate   L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate","GO:0005829///cytosol","GO:0008483///transaminase activity+++GO:0005515///protein binding+++GO:0097367///carbohydrate derivative binding+++GO:0016740///transferase activity+++GO:0004360///glutamine-fructose-6-phosphate transaminase (isomerizing) activity","GO:0006541///glutamine metabolic process+++GO:0006112///energy reserve metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:1901135///carbohydrate derivative metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:1901137///carbohydrate derivative biosynthetic process+++GO:0006487///protein N-linked glycosylation","glutamine-fructose-6-phosphate transaminase 2","[GFPT2_HUMAN|Reviewed]RecName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2; EC=2.6.1.16 {ECO:0000250|UniProtKB:P82808}; AltName: Full=D-fructose-6-phosphate amidotransferase 2; AltName: Full=Glutamine:fructose-6-phosphate amidotransferase 2; Short=GFAT 2; Short=GFAT2; AltName: Full=Hexosephosphate aminotransferase 2;+++[A0A0S2Z4W6_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 2 {ECO:0000313|EMBL:ALQ33953.1}; Flags: Fragment;+++[A0A0S2Z4X9_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 1 {ECO:0000313|EMBL:ALQ33952.1}; SubName: Full=Glutamine-fructose-6-phosphate transaminase 2, isoform CRA_b {ECO:0000313|EMBL:EAW53756.1}; Flags: Fragment;+++[B3KMR8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12445 fis, clone NT2RM1000256, highly similar to Glucosamine--fructose-6-phosphateaminotransferase (isomerizing) 2 {ECO:0000313|EMBL:BAG51080.1};+++[D6RAC1_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000422771}; Flags: Fragment;+++[E5RJP4_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000431125}; Flags: Fragment;"]
[9946,"'CRYZL1'",119,117,100,112,"04137///Mitophagy - animal+++04140///Autophagy - animal","H02132///Microcephaly syndrome",null,null,"GO:0005829///cytosol","GO:0050661///NADP binding+++GO:0016491///oxidoreductase activity+++GO:0003960///NADPH:quinone reductase activity","GO:1901661///quinone metabolic process+++GO:0055114///oxidation-reduction process","crystallin zeta like 1","[QORL1_HUMAN|Reviewed]RecName: Full=Quinone oxidoreductase-like protein 1; EC=1.-.-.-; AltName: Full=Protein 4P11; AltName: Full=Quinone oxidoreductase homolog 1; Short=QOH-1; AltName: Full=Zeta-crystallin homolog;+++[A0A0C4DG14_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000389209};+++[A6NHJ8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000355075};+++[A6NMA8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000290244};+++[A6NND8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000370951};+++[A8MZ10_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000382371};+++[C9JAL0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000405510}; Flags: Fragment;+++[C9JNR9_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000408385}; Flags: Fragment;+++[C9JQD0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000402844}; Flags: Fragment;+++[C9JZK8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399730};+++[C9K0F7_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000387660}; Flags: Fragment;+++[F8WF64_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399937};+++[H7C0X3_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000397318}; Flags: Fragment;+++[H7C2K1_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000406423}; Flags: Fragment;+++[H7C338_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000409387}; Flags: Fragment;+++[H7C3I5_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000412087}; Flags: Fragment;+++[H7C3S0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000413513}; Flags: Fragment;+++[Q8TBV9_HUMAN|Unreviewed]SubName: Full=CRYZL1 protein {ECO:0000313|EMBL:AAH22827.1}; Flags: Fragment;"]
[9948,"'WDR1'",10379,10265,9535,10059.6666666667,null,"H00948///Renal hypouricemia (RHUC)",null,null,"GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection+++GO:0042643///actomyosin, actin portion+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0002102///podosome+++GO:0043209///myelin sheath+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction","GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0007605///sensory perception of sound+++GO:0045214///sarcomere organization+++GO:0030042///actin filament depolymerization+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0040011///locomotion+++GO:0002576///platelet degranulation+++GO:0030834///regulation of actin filament depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0030220///platelet formation+++GO:0002446///neutrophil mediated immunity+++GO:0008360///regulation of cell shape+++GO:0043297///apical junction assembly+++GO:0042247///establishment of planar polarity of follicular epithelium+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0030043///actin filament fragmentation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:1990266///neutrophil migration+++GO:0030865///cortical cytoskeleton organization","WD repeat domain 1","[WDR1_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 1; AltName: Full=Actin-interacting protein 1; Short=AIP1; AltName: Full=NORI-1;+++[D6RD66_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000425481}; Flags: Fragment;+++[L8E9Y5_HUMAN|Unreviewed]SubName: Full=Alternative protein WDR1 {ECO:0000313|EMBL:CCQ43551.1};+++[Q53GN4_HUMAN|Unreviewed]SubName: Full=WD repeat domain 1, isoform CRA_a {ECO:0000313|EMBL:EAW92686.1}; SubName: Full=WD repeat-containing protein 1 isoform 1 variant {ECO:0000313|EMBL:BAD96617.1}; Flags: Fragment;+++[V9HWG7_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 52 {ECO:0000313|EMBL:ACJ13729.1};"]
[9949,"'AMMECR1'",217,133,219,189.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus","GO:0005515///protein binding","GO:0008150///biological_process","Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1","[AMMR1_HUMAN|Reviewed]RecName: Full=AMME syndrome candidate gene 1 protein;+++[A0A0S2Z4V0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33954.1}; Flags: Fragment;+++[A0A0S2Z4X0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33955.1}; SubName: Full=Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region, gene 1 {ECO:0000313|EMBL:EAX02663.1}; Flags: Fragment;"]
[995,"'CDC25C'",2,1,1,1.33333333333333,"05206///MicroRNAs in cancer+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation",null,"M00693///Cell cycle - G2/M transition+++M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0016787///hydrolase activity+++GO:0004725///protein tyrosine phosphatase activity","GO:0000086///G2/M transition of mitotic cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007283///spermatogenesis+++GO:0051301///cell division+++GO:0006470///protein dephosphorylation+++GO:0008283///cell proliferation+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division","cell division cycle 25C","[MPIP3_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 3; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25C;+++[B4DX61_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56262, highly similar to M-phase inducer phosphatase 3 {ECO:0000313|EMBL:BAG63273.1};+++[D6RD20_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427105}; Flags: Fragment;+++[D6RJC2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427251}; Flags: Fragment;+++[H0Y999_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000423525}; Flags: Fragment;+++[Q9H2F0_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25C splice variant 3 {ECO:0000313|EMBL:AAG41886.1}; Flags: Fragment;"]
[9950,"'GOLGA5'",942,841,777,853.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031985///Golgi cisterna+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005801///cis-Golgi network+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0017137///Rab GTPase binding","GO:0007030///Golgi organization+++GO:0048193///Golgi vesicle transport+++GO:0000301///retrograde transport, vesicle recycling within Golgi","golgin A5","[GOGA5_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 5; AltName: Full=Cell proliferation-inducing gene 31 protein; AltName: Full=Golgin-84; AltName: Full=Protein Ret-II; AltName: Full=RET-fused gene 5 protein;"]
[9951,"'HS3ST4'",106,102,63,90.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity","GO:0030201///heparan sulfate proteoglycan metabolic process","heparan sulfate-glucosamine 3-sulfotransferase 4","[HS3S4_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 4; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4; Short=3-OST-4; Short=Heparan sulfate 3-O-sulfotransferase 4; Short=h3-OST-4;+++[A5H458_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155}; Flags: Fragment;"]
[9953,"'HS3ST3B1'",429.51,387.02,239.75,352.093333333333,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0016740///transferase activity","GO:0006477///protein sulfation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification","heparan sulfate-glucosamine 3-sulfotransferase 3B1","[HS3SB_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; Short=3-OST-3B; Short=Heparan sulfate 3-O-sulfotransferase 3B1; Short=h3-OST-3B;"]
[9955,"'HS3ST3A1'",735.49,712.98,444.25,630.906666666667,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 3A1","[HS3SA_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Short=3-OST-3A; Short=Heparan sulfate 3-O-sulfotransferase 3A1; Short=h3-OST-3A;+++[J3KSX5_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9956,"'HS3ST2'",2,2,1,1.66666666666667,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0033871///[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity","GO:0007623///circadian rhythm+++GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 2","[HS3S2_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 2; EC=2.8.2.29; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2; Short=3-OST-2; Short=Heparan sulfate 3-O-sulfotransferase 2; Short=h3-OST-2;+++[H3BMR2_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9957,"'HS3ST1'",31,27,34,30.6666666666667,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0005796///Golgi lumen+++GO:0005794///Golgi apparatus","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity+++GO:0008146///sulfotransferase activity","GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 1","[HS3S1_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Short=3-OST-1; Short=Heparan sulfate 3-O-sulfotransferase 1; Short=h3-OST-1; Flags: Precursor;+++[A0A024R9R4_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[E9PDE3_HUMAN|Unreviewed]SubName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1 {ECO:0000313|Ensembl:ENSP00000425673}; Flags: Fragment;+++[Q05CH3_HUMAN|Unreviewed]SubName: Full=HS3ST1 protein {ECO:0000313|EMBL:AAH25735.1}; Flags: Fragment;"]
[9958,"'USP15'",391,269,320,326.666666666667,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity+++GO:0061649///ubiquitin modification-dependent histone binding+++GO:0008234///cysteine-type peptidase activity","GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0006508///proteolysis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030509///BMP signaling pathway+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0016579///protein deubiquitination","ubiquitin specific peptidase 15","[UBP15_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 15; EC=3.4.19.12 {ECO:0000269|PubMed:10444327, ECO:0000269|PubMed:16005295, ECO:0000269|PubMed:21947082, ECO:0000269|PubMed:22344298, ECO:0000269|PubMed:24852371, ECO:0000269|PubMed:27368102}; AltName: Full=Deubiquitinating enzyme 15; AltName: Full=Ubiquitin thioesterase 15; AltName: Full=Ubiquitin-specific-processing protease 15; AltName: Full=Unph-2; AltName: Full=Unph4;+++[F8VVY7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000449563}; Flags: Fragment;+++[F8VZG8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446843}; Flags: Fragment;+++[F8W0H4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447603}; Flags: Fragment;+++[H0YH96_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446559}; Flags: Fragment;+++[H0YHM4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447367}; Flags: Fragment;+++[H0YI26_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448372}; Flags: Fragment;+++[H0YI31_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448393}; Flags: Fragment;+++[Q2NL66_HUMAN|Unreviewed]SubName: Full=USP15 protein {ECO:0000313|EMBL:AAI10909.1};"]
[996,"'CDC27'",991,654,804,816.333333333333,"04111///Cell cycle - yeast+++04113///Meiosis - yeast+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0005680///anaphase-promoting complex+++GO:0005876///spindle microtubule+++GO:0016021///integral component of membrane+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019903///protein phosphatase binding+++GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0008283///cell proliferation+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle","cell division cycle 27","[CDC27_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 27 homolog; AltName: Full=Anaphase-promoting complex subunit 3; Short=APC3; AltName: Full=CDC27 homolog; Short=CDC27Hs; AltName: Full=H-NUC;+++[B4DL80_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57525, highly similar to Cell division cycle protein 27 homolog {ECO:0000313|EMBL:BAG59442.1};+++[E9PRZ6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432211};+++[F6QPS0_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432105};+++[G5EA36_HUMAN|Unreviewed]SubName: Full=Cell division cycle 27, isoform CRA_c {ECO:0000313|EMBL:EAW57688.1}; SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000437339};+++[I0EZ68_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24904.1}; Flags: Fragment;+++[I0EZ72_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24908.1}; Flags: Fragment;+++[I3L1K3_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000458904}; Flags: Fragment;+++[I3L225_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000459307}; Flags: Fragment;+++[I3L2Z8_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460061}; Flags: Fragment;+++[I3L328_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460132}; Flags: Fragment;+++[I3L394_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460279}; Flags: Fragment;+++[I3L3G1_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460424}; Flags: Fragment;+++[I3L3H6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460454}; Flags: Fragment;+++[I3L3Y5_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460830}; Flags: Fragment;+++[K7EMA6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000466424};"]
[9960,"'USP3'",195,172,204,190.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005654///nucleoplasm+++GO:0090543///Flemming body+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0016787///hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:1990841///promoter-specific chromatin binding+++GO:0008234///cysteine-type peptidase activity","GO:0006281///DNA repair+++GO:0031647///regulation of protein stability+++GO:0016578///histone deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0006508///proteolysis+++GO:0000122///negative regulation of transcription by RNA polymerase II","ubiquitin specific peptidase 3","[UBP3_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 3; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 3; AltName: Full=Ubiquitin thioesterase 3; AltName: Full=Ubiquitin-specific-processing protease 3;+++[H0YKU8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000452947}; Flags: Fragment;+++[H0YL81_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453093}; Flags: Fragment;+++[H0YLB7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453138};+++[H0YLG0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453194}; Flags: Fragment;+++[H0YLJ0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453228};+++[H0YM72_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453489}; Flags: Fragment;+++[H0YMI4_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};+++[H0YMP6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453688}; Flags: Fragment;+++[H0YMW1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453767};+++[H0YNK1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454043};+++[H0YNX9_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454197}; Flags: Fragment;+++[Q498Y2_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305}; Flags: Fragment;+++[Q6JHV3_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};"]
[9961,"'MVP'",3066,3112,2800,2992.66666666667,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00562///Inositol phosphate metabolism+++00564///Glycerophospholipid metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0034774///secretory granule lumen","GO:0042802///identical protein binding+++GO:0030246///carbohydrate binding+++GO:0030145///manganese ion binding+++GO:0019901///protein kinase binding+++GO:0019992///diacylglycerol binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity+++GO:0019903///protein phosphatase binding+++GO:0043178///alcohol binding","GO:0031953///negative regulation of protein autophosphorylation+++GO:0046341///CDP-diacylglycerol metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0023057///negative regulation of signaling+++GO:0015031///protein transport+++GO:0038127///ERBB signaling pathway+++GO:0051028///mRNA transport+++GO:0043312///neutrophil degranulation+++GO:0061099///negative regulation of protein tyrosine kinase activity","major vault protein","[MVP_HUMAN|Reviewed]RecName: Full=Major vault protein; Short=MVP; AltName: Full=Lung resistance-related protein;+++[Q6LAF4_HUMAN|Unreviewed]SubName: Full=LRP protein {ECO:0000313|EMBL:CAA77211.1}; Flags: Fragment;+++[X5D2M8_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform A {ECO:0000313|EMBL:AHW56524.1}; SubName: Full=Major vault protein, isoform CRA_c {ECO:0000313|EMBL:EAW79981.1}; SubName: Full=Testicular secretory protein Li 30 {ECO:0000313|EMBL:AEE61167.1}; Flags: Fragment;+++[X5D7K9_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform C {ECO:0000313|EMBL:AHW56525.1}; Flags: Fragment;+++[X5DNU0_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform B {ECO:0000313|EMBL:AHW56526.1}; Flags: Fragment;"]
[9962,"'SLC23A2'",2167,1473,3365,2335,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0009925///basal plasma membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0070890///sodium-dependent L-ascorbate transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015205///nucleobase transmembrane transporter activity","GO:0006979///response to oxidative stress+++GO:0019852///L-ascorbic acid metabolic process+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0015851///nucleobase transport","solute carrier family 23 member 2","[S23A2_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 2; AltName: Full=Na(+)/L-ascorbic acid transporter 2; AltName: Full=Nucleobase transporter-like 1 protein; AltName: Full=Sodium-dependent vitamin C transporter 2; Short=hSVCT2; AltName: Full=Yolk sac permease-like molecule 2;+++[A0A140VK48_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_b {ECO:0000313|EMBL:EAX10439.1}; SubName: Full=Testicular secretory protein Li 48 {ECO:0000313|EMBL:AEE61185.1};"]
[9963,"'SLC23A1'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043229///intracellular organelle+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005737///cytoplasm+++GO:0043292///contractile fiber+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008520///L-ascorbate:sodium symporter activity+++GO:0005215///transporter activity+++GO:0015293///symporter activity+++GO:0005515///protein binding+++GO:0070890///sodium-dependent L-ascorbate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity+++GO:0015205///nucleobase transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015081///sodium ion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0035725///sodium ion transmembrane transport+++GO:0009636///response to toxic substance+++GO:0070837///dehydroascorbic acid transport+++GO:0006811///ion transport+++GO:0019852///L-ascorbic acid metabolic process+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0015851///nucleobase transport+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0006814///sodium ion transport+++GO:0030324///lung development","solute carrier family 23 member 1","[S23A1_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 1; AltName: Full=Na(+)/L-ascorbic acid transporter 1; AltName: Full=Sodium-dependent vitamin C transporter 1; Short=hSVCT1; AltName: Full=Yolk sac permease-like molecule 3;+++[D3DVZ8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_a {ECO:0000313|EMBL:EAX10440.1};+++[H0Y544_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 2 {ECO:0000313|Ensembl:ENSP00000396364}; Flags: Fragment;+++[H0Y902_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|Ensembl:ENSP00000422688}; Flags: Fragment;+++[H0YAJ1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|Ensembl:ENSP00000427271}; Flags: Fragment;+++[Q4ZGM1_HUMAN|Unreviewed]SubName: Full=Sodium-dependent vitamin C transporter 2 variant II {ECO:0000313|EMBL:AAY26157.1}; Flags: Fragment;"]
[9966,"'TNFSF15'",0,1,2.23,1.07666666666667,"04060///Cytokine-cytokine receptor interaction","H00286///Crohn's disease",null,null,"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0010469///regulation of signaling receptor activity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006915///apoptotic process+++GO:0042107///cytokine metabolic process+++GO:0006955///immune response+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007165///signal transduction","TNF superfamily member 15","[TNF15_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 15; AltName: Full=TNF ligand-related molecule 1; AltName: Full=Vascular endothelial cell growth inhibitor; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, membrane form; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, secreted form;+++[A0A0U5JA19_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 1B {ECO:0000313|EMBL:CTQ86078.1};+++[D9N2U0_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor (Ligand) superfamily, member 15 {ECO:0000313|EMBL:BAJ13472.1}; Flags: Fragment;+++[X6R8I9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 15 {ECO:0000313|Ensembl:ENSP00000363156};"]
[9967,"'THRAP3'",1895,1493,1621,1669.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0003723///RNA binding+++GO:0042809///vitamin D receptor binding+++GO:0005515///protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0051219///phosphoprotein binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0038023///signaling receptor activity+++GO:0005524///ATP binding+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042753///positive regulation of circadian rhythm+++GO:0048255///mRNA stabilization+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0048511///rhythmic process+++GO:0008380///RNA splicing+++GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","thyroid hormone receptor associated protein 3","[TR150_HUMAN|Reviewed]RecName: Full=Thyroid hormone receptor-associated protein 3; AltName: Full=BCLAF1 and THRAP3 family member 2 {ECO:0000312|HGNC:HGNC:22964}; AltName: Full=Thyroid hormone receptor-associated protein complex 150 kDa component; Short=Trap150;+++[E9PML1_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor-associated protein 3 {ECO:0000313|Ensembl:ENSP00000433066}; Flags: Fragment;+++[Q05D20_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH19076.1}; Flags: Fragment;+++[Q6P0P7_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH65519.1}; Flags: Fragment;+++[Q6PJV4_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH10997.1}; Flags: Fragment;+++[Q7Z5U1_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH54046.1}; Flags: Fragment;"]
[9968,"'MED12'",1130,946,1071,1049,"04919///Thyroid hormone signaling pathway","H01640///Uterine leiomyoma+++H00894///FG syndrome (FGS)+++H00889///MED12-related disorders+++H01795///Blepharophimosis-mental retardation syndrome (BMRS)",null,null,"GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:1904115///axon cytoplasm+++GO:0005829///cytosol+++GO:0016592///mediator complex+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion","GO:0003682///chromatin binding+++GO:1901612///cardiolipin binding+++GO:0016787///hydrolase activity+++GO:0008017///microtubule binding+++GO:0042809///vitamin D receptor binding+++GO:0008289///lipid binding+++GO:0019904///protein domain specific binding+++GO:0070300///phosphatidic acid binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008134///transcription factor binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000287///magnesium ion binding+++GO:0003712///transcription coregulator activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003924///GTPase activity+++GO:0038023///signaling receptor activity+++GO:0019900///kinase binding+++GO:0005525///GTP binding+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0046966///thyroid hormone receptor binding","GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051602///response to electrical stimulus+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0050896///response to stimulus+++GO:0006915///apoptotic process+++GO:0014003///oligodendrocyte development+++GO:0007601///visual perception+++GO:0090398///cellular senescence+++GO:0008053///mitochondrial fusion+++GO:0048312///intracellular distribution of mitochondria+++GO:0007568///aging+++GO:0019896///axonal transport of mitochondrion+++GO:0090102///cochlea development+++GO:0060070///canonical Wnt signaling pathway+++GO:0021510///spinal cord development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0070584///mitochondrion morphogenesis+++GO:0048568///embryonic organ development+++GO:0036342///post-anal tail morphogenesis+++GO:0019827///stem cell population maintenance+++GO:0030521///androgen receptor signaling pathway+++GO:0097749///membrane tubulation+++GO:0036444///calcium import into the mitochondrion+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000002///mitochondrial genome maintenance+++GO:0016567///protein ubiquitination+++GO:0021915///neural tube development+++GO:0071333///cellular response to glucose stimulus+++GO:0007492///endoderm development+++GO:0061025///membrane fusion+++GO:0051259///protein complex oligomerization+++GO:0001843///neural tube closure+++GO:0071456///cellular response to hypoxia+++GO:0060041///retina development in camera-type eye+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0046039///GTP metabolic process+++GO:1900006///positive regulation of dendrite development+++GO:0090245///axis elongation involved in somitogenesis+++GO:0007507///heart development+++GO:0000266///mitochondrial fission+++GO:1990403///embryonic brain development+++GO:1900078///positive regulation of cellular response to insulin stimulus+++GO:0007007///inner mitochondrial membrane organization+++GO:0014044///Schwann cell development+++GO:0014850///response to muscle activity+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:1905232///cellular response to L-glutamate+++GO:0031667///response to nutrient levels+++GO:0001756///somitogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1904643///response to curcumin+++GO:0043066///negative regulation of apoptotic process+++GO:0014042///positive regulation of neuron maturation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0007005///mitochondrion organization+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0010636///positive regulation of mitochondrial fusion","mediator complex subunit 12","[MED12_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 12; AltName: Full=Activator-recruited cofactor 240 kDa component; Short=ARC240; AltName: Full=CAG repeat protein 45; AltName: Full=Mediator complex subunit 12; AltName: Full=OPA-containing protein; AltName: Full=Thyroid hormone receptor-associated protein complex 230 kDa component; Short=Trap230; AltName: Full=Trinucleotide repeat-containing gene 11 protein;+++[A0A2R8Y3X5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493673};+++[A0A2R8Y4G4_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494015}; Flags: Fragment;+++[A0A2R8Y4Q3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493988};+++[A0A2R8Y514_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494210};+++[A0A2R8Y5E2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494736}; Flags: Fragment;+++[A0A2R8Y5G3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494509};+++[A0A2R8YD53_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494273};+++[A0A2R8YDM2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494725};+++[A0A2R8YE54_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495289};+++[A0A2R8YE78_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494121};+++[A0A2R8YFD1_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495028}; Flags: Fragment;+++[A0A2R8YGE5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495943}; Flags: Fragment;+++[A8MXB6_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376232}; Flags: Fragment;+++[C9JMB8_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376231};+++[C9JY58_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000399877}; Flags: Fragment;+++[G0KYB4_HUMAN|Unreviewed]SubName: Full=Putative mediator subunit 12 short {ECO:0000313|EMBL:CAZ90628.1}; Flags: Fragment;+++[H7C141_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000398358}; Flags: Fragment;+++[H7C191_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000399084}; Flags: Fragment;+++[H7C274_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000404373}; Flags: Fragment;+++[H7C321_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000409084}; Flags: Fragment;+++[H7C3G2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000411699}; Flags: Fragment;+++[Q7Z2E0_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81050.1}; Flags: Fragment;+++[Q7Z2F1_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81080.1}; Flags: Fragment;+++[Q7Z2F4_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81020.1}; Flags: Fragment;+++[Q7Z2K3_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81092.1}; Flags: Fragment;+++[Q7Z3Z5_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000333125}; SubName: Full=Mediator of RNA polymerase II transcription, subunit 12 homolog (Yeast), isoform CRA_e {ECO:0000313|EMBL:EAX05318.1}; SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81137.1};+++[Q8WWP6_HUMAN|Unreviewed]SubName: Full=OPA-containing protein {ECO:0000313|EMBL:CAC84084.1}; Flags: Fragment;"]
[9969,"'MED13'",689,392,456,512.333333333333,"04919///Thyroid hormone signaling pathway","H00550///Complete transposition of the great arteries",null,null,"GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003713///transcription coactivator activity+++GO:0042809///vitamin D receptor binding+++GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:1904168///negative regulation of thyroid hormone receptor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030521///androgen receptor signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0070328///triglyceride homeostasis+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006357///regulation of transcription by RNA polymerase II","mediator complex subunit 13","[MED13_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13; AltName: Full=Activator-recruited cofactor 250 kDa component; Short=ARC250; AltName: Full=Mediator complex subunit 13; AltName: Full=Thyroid hormone receptor-associated protein 1; AltName: Full=Thyroid hormone receptor-associated protein complex 240 kDa component; Short=Trap240; AltName: Full=Vitamin D3 receptor-interacting protein complex component DRIP250; Short=DRIP250;+++[A0A024QZ75_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000256|RuleBase:RU364134};+++[J3QRB7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000313|Ensembl:ENSP00000464131}; Flags: Fragment;"]
[997,"'CDC34'",1189,1269,1175,1211,"04120///Ubiquitin mediated proteolysis+++05168///Herpes simplex infection",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0005515///protein binding","GO:0035458///cellular response to interferon-beta+++GO:0006270///DNA replication initiation+++GO:0090261///positive regulation of inclusion body assembly+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0070848///response to growth factor+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0000209///protein polyubiquitination+++GO:0006464///cellular protein modification process+++GO:0007049///cell cycle","cell division cycle 34","[UB2R1_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 R1; EC=2.3.2.23 {ECO:0000269|PubMed:12037680, ECO:0000269|PubMed:17698585, ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:20347421}; AltName: Full=(E3-independent) E2 ubiquitin-conjugating enzyme R1; EC=2.3.2.24 {ECO:0000269|PubMed:17588522}; AltName: Full=E2 ubiquitin-conjugating enzyme R1; AltName: Full=Ubiquitin-conjugating enzyme E2-32 kDa complementing; AltName: Full=Ubiquitin-conjugating enzyme E2-CDC34; AltName: Full=Ubiquitin-protein ligase R1;+++[A0A024R1Z1_HUMAN|Unreviewed]SubName: Full=Cell division cycle 34, isoform CRA_a {ECO:0000313|EMBL:EAW61191.1};+++[U3KPV8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475282}; Flags: Fragment;+++[U3KQ77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475610}; Flags: Fragment;+++[U3KQP9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000476107}; Flags: Fragment;"]
[9970,"'NR1I3'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0004882///androgen receptor activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding+++GO:0008134///transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004887///thyroid hormone receptor activity+++GO:0003707///steroid hormone receptor activity","GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030521///androgen receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","nuclear receptor subfamily 1 group I member 3","[NR1I3_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group I member 3; AltName: Full=Constitutive activator of retinoid response; Short=Constitutive active response; AltName: Full=Constitutive androstane receptor; Short=CAR; AltName: Full=Orphan nuclear receptor MB67;+++[B6ZGT2_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor {ECO:0000313|EMBL:BAH02293.1};+++[B7Z8R7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000427034}; SubName: Full=cDNA FLJ56764, highly similar to Orphan nuclear receptor NR1I3 {ECO:0000313|EMBL:BAH14053.1}; SubName: Full=cDNA, FLJ79107, highly similar to Orphan nuclear receptor NR1I3 {ECO:0000313|EMBL:BAH14579.1};+++[C0H5Y2_HUMAN|Unreviewed]SubName: Full=NR1I3 protein {ECO:0000313|EMBL:AAH69651.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000424834}; SubName: Full=Nuclear receptor subfamily 1, group I, member 3, isoform CRA_c {ECO:0000313|EMBL:EAW52610.1};+++[D6REZ7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000421588};+++[E9PCF2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000423089};+++[F1DAL4_HUMAN|Unreviewed]SubName: Full=Constitutive androstane nuclear receptor {ECO:0000313|EMBL:ADZ17385.1};+++[Q6GZ69_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV21 {ECO:0000313|EMBL:AAT47179.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000426016};+++[Q6GZ70_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV19 {ECO:0000313|EMBL:AAT47177.1}; SubName: Full=Constitutive androstane receptor SV20 {ECO:0000313|EMBL:AAT47178.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000422982};+++[Q6GZ72_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV17 {ECO:0000313|EMBL:AAT47175.1}; SubName: Full=Constitutive androstane receptor SV18 {ECO:0000313|EMBL:AAT47176.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000421374};+++[Q6GZ74_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV16 {ECO:0000313|EMBL:AAT47174.1}; Flags: Fragment;+++[Q6GZ75_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV15 {ECO:0000313|EMBL:AAT47173.1}; Flags: Fragment;+++[Q6GZ81_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV10 {ECO:0000313|EMBL:AAT47168.1}; SubName: Full=Constitutive androstane receptor SV4 {ECO:0000313|EMBL:AAT47162.1}; SubName: Full=Constitutive androstane receptor SV9 {ECO:0000313|EMBL:AAT47167.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000423007};+++[Q6GZ88_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV2 {ECO:0000313|EMBL:AAT47160.1};"]
[9972,"'NUP153'",647,504,609,586.666666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005634///nucleus+++GO:0005623///cell+++GO:0005730///nucleolus+++GO:0005643///nuclear pore+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0043657///host cell+++GO:0044613///nuclear pore central transport channel+++GO:0034399///nuclear periphery+++GO:0044615///nuclear pore nuclear basket+++GO:0016020///membrane+++GO:0042405///nuclear inclusion body","GO:0017056///structural constituent of nuclear pore+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0008139///nuclear localization sequence binding","GO:0075732///viral penetration into host nucleus+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0046718///viral entry into host cell+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0046832///negative regulation of RNA export from nucleus+++GO:0016032///viral process+++GO:0006913///nucleocytoplasmic transport","nucleoporin 153","[NU153_HUMAN|Reviewed]RecName: Full=Nuclear pore complex protein Nup153; AltName: Full=153 kDa nucleoporin; AltName: Full=Nucleoporin Nup153;+++[A0A024QZW7_HUMAN|Unreviewed]SubName: Full=Nucleoporin 153kDa, isoform CRA_a {ECO:0000313|EMBL:EAW55385.1};"]
[9973,"'CCS'",205,255,194,218,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004784///superoxide dismutase activity+++GO:0016532///superoxide dismutase copper chaperone activity","GO:0015680///protein maturation by copper ion transfer+++GO:0034599///cellular response to oxidative stress+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0055114///oxidation-reduction process+++GO:0006801///superoxide metabolic process+++GO:0019430///removal of superoxide radicals+++GO:0030001///metal ion transport","copper chaperone for superoxide dismutase","[CCS_HUMAN|Reviewed]RecName: Full=Copper chaperone for superoxide dismutase; AltName: Full=Superoxide dismutase copper chaperone;+++[A0A024R5B4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase, isoform CRA_a {ECO:0000313|EMBL:EAW74551.1};+++[E9PK03_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000433609};+++[E9PP76_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000436379}; Flags: Fragment;+++[J3KNF4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000307870};"]
[9975,"'NR1D2'",319,196,221,245.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex","GO:0038023///signaling receptor activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003707///steroid hormone receptor activity","GO:0042752///regulation of circadian rhythm+++GO:0050727///regulation of inflammatory response+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0033993///response to lipid+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0048511///rhythmic process+++GO:0097009///energy homeostasis+++GO:0030154///cell differentiation+++GO:0019216///regulation of lipid metabolic process+++GO:0009755///hormone-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0055088///lipid homeostasis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030522///intracellular receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0043401///steroid hormone mediated signaling pathway","nuclear receptor subfamily 1 group D member 2","[NR1D2_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group D member 2; AltName: Full=Orphan nuclear hormone receptor BD73; AltName: Full=Rev-erb alpha-related receptor; Short=RVR; AltName: Full=Rev-erb-beta; AltName: Full=V-erbA-related protein 1-related; Short=EAR-1R;+++[B4DXD3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 2 {ECO:0000313|EMBL:ADZ17342.1}; SubName: Full=Nuclear receptor subfamily 1, group D, member 2, isoform CRA_b {ECO:0000313|EMBL:EAW64341.1}; SubName: Full=cDNA FLJ51368, highly similar to Orphan nuclear receptor NR1D2 {ECO:0000313|EMBL:BAG63345.1};+++[B6ZGS3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1, group D, member 2 {ECO:0000313|EMBL:BAH02284.1};+++[F1D8P2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 1 {ECO:0000313|EMBL:ADZ17341.1};+++[Q6I9S1_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:CAG33715.1};+++[Q6NSM0_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH70035.1}; SubName: Full=Nuclear receptor subfamily 1 group D member 2 {ECO:0000313|Ensembl:ENSP00000373283};+++[Q96B66_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH15929.1}; Flags: Fragment;"]
[9976,"'CLEC2B'",0,0,4,1.33333333333333,"05167///Kaposi's sarcoma-associated herpesvirus infection",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0050776///regulation of immune response+++GO:0032199///reverse transcription involved in RNA-mediated transposition","C-type lectin domain family 2 member B","[CLC2B_HUMAN|Reviewed]RecName: Full=C-type lectin domain family 2 member B; AltName: Full=Activation-induced C-type lectin; AltName: Full=C-type lectin superfamily member 2; AltName: Full=IFN-alpha-2b-inducing-related protein 1;"]
[9978,"'RBX1'",343,381,310,344.666666666667,"04110///Cell cycle+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++04114///Oocyte meiosis+++03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04310///Wnt signaling pathway+++04341///Hedgehog signaling pathway - fly+++05200///Pathways in cancer+++04710///Circadian rhythm+++04350///TGF-beta signaling pathway+++04111///Cell cycle - yeast",null,"M00385///Cul4-DDB1-DDB2 complex+++M00407///SCF-CDC4 complex+++M00381///SCF-SKP2 complex+++M00411///SCF-GRR1 complex+++M00383///ECV complex+++M00382///SCF-FBS complex+++M00386///Cul4-DDB1-CSA complex+++M00380///SCF-BTRC complex+++M00387///SCF-FBW7 complex+++M00384///Cul3-SPOP complex+++M00379///SCF-MET30 complex",null,"GO:0005654///nucleoplasm+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0030891///VCB complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043224///nuclear SCF ubiquitin ligase complex","GO:0044877///protein-containing complex binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008134///transcription factor binding+++GO:0019788///NEDD8 transferase activity+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0046872///metal ion binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0097602///cullin family protein binding+++GO:0061630///ubiquitin protein ligase activity","GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0070911///global genome nucleotide-excision repair+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016032///viral process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006281///DNA repair+++GO:0010265///SCF complex assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006513///protein monoubiquitination+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0043687///post-translational protein modification+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0045116///protein neddylation+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000209///protein polyubiquitination+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000165///MAPK cascade+++GO:0030163///protein catabolic process","ring-box 1","[RBX1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RBX1; EC=2.3.2.27 {ECO:0000269|PubMed:11027288}; EC=2.3.2.32 {ECO:0000269|PubMed:11027288}; AltName: Full=E3 ubiquitin-protein transferase RBX1 {ECO:0000305}; AltName: Full=Protein ZYP; AltName: Full=RING finger protein 75; AltName: Full=RING-box protein 1; Short=Rbx1; AltName: Full=Regulator of cullins 1; Short=ROC1 {ECO:0000303|PubMed:10230407}; Contains: RecName: Full=E3 ubiquitin-protein ligase RBX1, N-terminally processed; AltName: Full=E3 ubiquitin-protein transferase RBX1, N-terminally processed {ECO:0000305};"]
[998,"'CDC42'",3148,2854,2858,2953.33333333333,"05131///Shigellosis+++05211///Renal cell carcinoma+++04062///Chemokine signaling pathway+++04530///Tight junction+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04810///Regulation of actin cytoskeleton+++05132///Salmonella infection+++05130///Pathogenic Escherichia coli infection+++05205///Proteoglycans in cancer+++04360///Axon guidance+++05165///Human papillomavirus infection+++05212///Pancreatic cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer+++04520///Adherens junction+++04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04011///MAPK signaling pathway - yeast+++04722///Neurotrophin signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++04912///GnRH signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04014///Ras signaling pathway+++05203///Viral carcinogenesis+++04144///Endocytosis+++04010///MAPK signaling pathway+++04370///VEGF signaling pathway+++04660///T cell receptor signaling pathway",{"$nulls":3},"GO:0045335///phagocytic vesicle+++GO:0043005///neuron projection+++GO:0005813///centrosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0030496///midbody+++GO:0000139///Golgi membrane+++GO:0045177///apical part of cell+++GO:0031256///leading edge membrane+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0070062///extracellular exosome+++GO:0005819///spindle+++GO:0051233///spindle midzone+++GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0000322///storage vacuole+++GO:0030175///filopodium+++GO:0017119///Golgi transport complex+++GO:0072686///mitotic spindle+++GO:0032991///protein-containing complex+++GO:0071944///cell periphery","GO:0004674///protein serine/threonine kinase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0005525///GTP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0031996///thioesterase binding+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0030742///GTP-dependent protein binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0032427///GBD domain binding+++GO:0019901///protein kinase binding","GO:0048013///ephrin receptor signaling pathway+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007097///nuclear migration+++GO:0060047///heart contraction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0072384///organelle transport along microtubule+++GO:0007163///establishment or maintenance of cell polarity+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0030154///cell differentiation+++GO:0031295///T cell costimulation+++GO:0090316///positive regulation of intracellular protein transport+++GO:0030031///cell projection assembly+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0030307///positive regulation of cell growth+++GO:0051489///regulation of filopodium assembly+++GO:0060997///dendritic spine morphogenesis+++GO:0031333///negative regulation of protein complex assembly+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090135///actin filament branching+++GO:0036336///dendritic cell migration+++GO:0007266///Rho protein signal transduction+++GO:0043497///regulation of protein heterodimerization activity+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0006897///endocytosis+++GO:0007088///regulation of mitotic nuclear division+++GO:0016567///protein ubiquitination+++GO:0006468///protein phosphorylation+++GO:0051491///positive regulation of filopodium assembly+++GO:0051492///regulation of stress fiber assembly+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0032467///positive regulation of cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0099563///modification of synaptic structure+++GO:0046330///positive regulation of JNK cascade+++GO:0034332///adherens junction organization+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0034613///cellular protein localization+++GO:0034329///cell junction assembly+++GO:0007399///nervous system development+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0045740///positive regulation of DNA replication+++GO:0007596///blood coagulation+++GO:0032488///Cdc42 protein signal transduction+++GO:0048664///neuron fate determination+++GO:0007229///integrin-mediated signaling pathway+++GO:0021762///substantia nigra development+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0051647///nucleus localization+++GO:0051835///positive regulation of synapse structural plasticity+++GO:0007030///Golgi organization+++GO:0010591///regulation of lamellipodium assembly+++GO:0030225///macrophage differentiation+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0046847///filopodium assembly+++GO:0051683///establishment of Golgi localization+++GO:0008360///regulation of cell shape+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0003161///cardiac conduction system development+++GO:0007264///small GTPase mediated signal transduction+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0051301///cell division+++GO:0038189///neuropilin signaling pathway+++GO:0002040///sprouting angiogenesis+++GO:0060661///submandibular salivary gland formation+++GO:0043085///positive regulation of catalytic activity","cell division cycle 42","[CDC42_HUMAN|Reviewed]RecName: Full=Cell division control protein 42 homolog; AltName: Full=G25K GTP-binding protein; Flags: Precursor;+++[A0A024RAE4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a {ECO:0000313|EMBL:EAW95004.1};+++[A0A024RAE6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_c {ECO:0000313|EMBL:EAW95009.1};+++[Q5JYX0_HUMAN|Unreviewed]SubName: Full=Cell division control protein 42 homolog {ECO:0000313|Ensembl:ENSP00000398327}; Flags: Fragment;"]
[9980,"'DOP1B'",399,352,330,360.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0005802///trans-Golgi network+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0050890///cognition+++GO:0007275///multicellular organism development+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","DOP1 leucine zipper like protein B","[DOP2_HUMAN|Reviewed]RecName: Full=Protein dopey-2;+++[F8W8U9_HUMAN|Unreviewed]SubName: Full=DOP1 leucine zipper-like protein B {ECO:0000313|Ensembl:ENSP00000270190}; Flags: Fragment;"]
[9982,"'FGFBP1'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0005576///extracellular region","GO:0017134///fibroblast growth factor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0019838///growth factor binding","GO:0008285///negative regulation of cell proliferation+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007267///cell-cell signaling+++GO:0007165///signal transduction","fibroblast growth factor binding protein 1","[FGFP1_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor-binding protein 1; Short=FGF-BP; Short=FGF-BP1; Short=FGF-binding protein 1; Short=FGFBP-1; AltName: Full=17 kDa heparin-binding growth factor-binding protein; Short=17 kDa HBGF-binding protein; Short=HBp17; Flags: Precursor;"]
[9984,"'THOC1'",106,106,115,109,"03040///Spliceosome+++03013///RNA transport",null,"M00405///THC complex+++M00406///TREX complex",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0000347///THO complex+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000445///THO complex part of transcription export complex+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0000346///transcription export complex+++GO:0016607///nuclear speck","GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0051028///mRNA transport+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0006406///mRNA export from nucleus+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0007165///signal transduction+++GO:0008380///RNA splicing+++GO:0031297///replication fork processing+++GO:0006396///RNA processing+++GO:0000018///regulation of DNA recombination+++GO:0048297///negative regulation of isotype switching to IgA isotypes+++GO:0031124///mRNA 3'-end processing","THO complex 1","[THOC1_HUMAN|Reviewed]RecName: Full=THO complex subunit 1; Short=Tho1; AltName: Full=Nuclear matrix protein p84; Short=p84N5; AltName: Full=hTREX84;+++[A0A087WWS1_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000480460};+++[A0A087WY84_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000481599};+++[J3KRD7_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000461943};+++[J3KT14_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000462757};+++[J3QQZ3_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000463965};+++[R4GMN4_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473276}; Flags: Fragment;+++[R4GN58_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473499}; Flags: Fragment;"]
[9985,"'REC8'",5130,5263,5076,5156.33333333333,"04114///Oocyte meiosis",{"$nulls":3},"GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0030893///meiotic cohesin complex+++GO:0000800///lateral element+++GO:0005694///chromosome+++GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000795///synaptonemal complex+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0008278///cohesin complex+++GO:0001673///male germ cell nucleus+++GO:0034991///nuclear meiotic cohesin complex","GO:0003682///chromatin binding","GO:0007130///synaptonemal complex assembly+++GO:0009566///fertilization+++GO:0000724///double-strand break repair via homologous recombination+++GO:0007059///chromosome segregation+++GO:0007141///male meiosis I+++GO:0007062///sister chromatid cohesion+++GO:0072520///seminiferous tubule development+++GO:0007283///spermatogenesis+++GO:0001556///oocyte maturation+++GO:0051321///meiotic cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0007286///spermatid development+++GO:0006302///double-strand break repair+++GO:0007129///synapsis","REC8 meiotic recombination protein","[REC8_HUMAN|Reviewed]RecName: Full=Meiotic recombination protein REC8 homolog; AltName: Full=Cohesin Rec8p;+++[A0A075B715_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000452701}; Flags: Fragment;+++[H0YM87_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453506}; Flags: Fragment;+++[H0YMV7_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453763}; Flags: Fragment;"]
[9986,"'RCE1'",139,176,151,155.333333333333,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis",null,null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0016787///hydrolase activity","GO:0071586///CAAX-box protein processing+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","Ras converting CAAX endopeptidase 1","[FACE2_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 2; EC=3.4.22.-; AltName: Full=Farnesylated proteins-converting enzyme 2; Short=FACE-2; AltName: Full=Prenyl protein-specific endoprotease 2; AltName: Full=RCE1 homolog; Short=hRCE1;+++[A0A024R5B6_HUMAN|Unreviewed]SubName: Full=RCE1 homolog, prenyl protein peptidase (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW74566.1};+++[E9PI08_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436600};+++[E9PKA7_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000435409};+++[E9PPV9_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436300};+++[Q0P5W4_HUMAN|Unreviewed]SubName: Full=RCE1 protein {ECO:0000313|EMBL:AAH52622.1}; Flags: Fragment;"]
[9987,"'HNRNPDL'",1011,1032,942,995,null,"H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005681///spliceosomal complex+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0043565///sequence-specific DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0034046///poly(G) binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0008143///poly(A) binding","GO:0010468///regulation of gene expression+++GO:0006396///RNA processing+++GO:0035722///interleukin-12-mediated signaling pathway","heterogeneous nuclear ribonucleoprotein D like","[HNRDL_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like; Short=hnRNP D-like; Short=hnRNP DL; AltName: Full=AU-rich element RNA-binding factor; AltName: Full=JKT41-binding protein; AltName: Full=Protein laAUF1;+++[A0A024RDF6_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_a {ECO:0000313|EMBL:EAX05891.1};+++[A0A087WU03_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like {ECO:0000313|Ensembl:ENSP00000478269};+++[A0A087WUK2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_b {ECO:0000313|EMBL:EAX05890.1};"]
[9988,"'DMTF1'",350,326,320,332,{"$nulls":4},"GO:0005829///cytosol+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0005654///nucleoplasm+++GO:0005576///extracellular region","GO:0003700///DNA-binding transcription factor activity+++GO:0005178///integrin binding+++GO:0003677///DNA binding+++GO:0005509///calcium ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0050840///extracellular matrix binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0070173///regulation of enamel mineralization+++GO:0031214///biomineral tissue development+++GO:0043687///post-translational protein modification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030198///extracellular matrix organization+++GO:0007049///cell cycle+++GO:0044267///cellular protein metabolic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0001503///ossification+++GO:0006355///regulation of transcription, DNA-templated","cyclin D binding myb like transcription factor 1","[DMTF1_HUMAN|Reviewed]RecName: Full=Cyclin-D-binding Myb-like transcription factor 1; Short=hDMTF1; AltName: Full=Cyclin-D-interacting Myb-like protein 1; Short=hDMP1;+++[A0A1D5RMP8_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000406384}; Flags: Fragment;+++[B3KMJ8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ11211 fis, clone PLACE1007955, highly similar to Homo sapiens cyclin D binding myb-like transcription factor 1 (DMTF1), mRNA {ECO:0000313|EMBL:BAG51010.1};+++[C9J4F7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000411858}; Flags: Fragment;+++[C9J8Y5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000397490}; Flags: Fragment;+++[C9JED5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000415382}; Flags: Fragment;+++[C9JFR2_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416499}; Flags: Fragment;+++[C9JGT5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416307}; Flags: Fragment;+++[C9JLR5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413722}; Flags: Fragment;+++[C9JVQ7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000393370}; Flags: Fragment;+++[C9JZZ6_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000387712}; Flags: Fragment;+++[C9K0K9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413118}; Flags: Fragment;+++[C9K0L9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000401129}; Flags: Fragment;+++[D6W5P0_HUMAN|Unreviewed]SubName: Full=Cyclin D binding myb-like transcription factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW76964.1};+++[E7EPA0_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000402627};+++[F8VXY9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000448775};+++[H7C388_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000410288}; Flags: Fragment;+++[J3KRC1_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000461920}; Flags: Fragment;+++[J3QKU5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463239}; Flags: Fragment;+++[J3QLN9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463638};+++[J3QLW3_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463735}; Flags: Fragment;"]
[9989,"'PPP4R1'",664,579,632,625,"05200///Pathways in cancer+++05212///Pancreatic cancer+++04014///Ras signaling pathway",{"$nulls":3},"GO:0030289///protein phosphatase 4 complex","GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0050790///regulation of catalytic activity","protein phosphatase 4 regulatory subunit 1","[PP4R1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1;+++[F8WAJ9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000285124};+++[J3KRU1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462161}; Flags: Fragment;+++[J3KSB0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462399}; Flags: Fragment;+++[J3KSH2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462485};+++[J3KSS1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462621};+++[J3QL26_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463345}; Flags: Fragment;+++[J3QLA6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463459}; Flags: Fragment;+++[J3QQV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463909}; Flags: Fragment;+++[J3QRV2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000464394};+++[Q6RXQ6_HUMAN|Unreviewed]SubName: Full=Protein serine/threonine phosphatase 4 subunit {ECO:0000313|EMBL:AAS59409.1}; Flags: Fragment;"]
[999,"'CDH1'",6123,4126,5793,5347.33333333333,"05218///Melanoma+++05219///Bladder cancer+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04390///Hippo signaling pathway+++04371///Apelin signaling pathway+++04015///Rap1 signaling pathway+++05216///Thyroid cancer+++05226///Gastric cancer+++04520///Adherens junction","H00032///Thyroid cancer+++H00025///Penile cancer+++H00054///Nasopharyngeal cancer+++H00018///Gastric cancer",null,null,"GO:0015629///actin cytoskeleton+++GO:0043296///apical junction complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0005913///cell-cell adherens junction+++GO:0005576///extracellular region+++GO:0016600///flotillin complex+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0098794///postsynapse+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016342///catenin complex+++GO:0005802///trans-Golgi network+++GO:0005768///endosome+++GO:0016328///lateral plasma membrane","GO:0050839///cell adhesion molecule binding+++GO:0032794///GTPase activating protein binding+++GO:0005509///calcium ion binding+++GO:0030506///ankyrin binding+++GO:0045296///cadherin binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0071681///cellular response to indole-3-methanol+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0009636///response to toxic substance+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0042307///positive regulation of protein import into nucleus+++GO:0071285///cellular response to lithium ion+++GO:0035635///entry of bacterium into host cell+++GO:0030198///extracellular matrix organization+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0072659///protein localization to plasma membrane+++GO:0031175///neuron projection development","cadherin 1","[CADH1_HUMAN|Reviewed]RecName: Full=Cadherin-1; AltName: Full=CAM 120/80; AltName: Full=Epithelial cadherin; Short=E-cadherin; AltName: Full=Uvomorulin; AltName: CD_antigen=CD324; Contains: RecName: Full=E-Cad/CTF1; Contains: RecName: Full=E-Cad/CTF2; Contains: RecName: Full=E-Cad/CTF3; Flags: Precursor;+++[A0A0U2ZQU7_HUMAN|Unreviewed]SubName: Full=E-cadherin 1 {ECO:0000313|EMBL:ALS87660.1};+++[B3GN61_HUMAN|Unreviewed]SubName: Full=Truncated E-cadherin {ECO:0000313|EMBL:ACD87624.1};+++[Q9UII7_HUMAN|Unreviewed]SubName: Full=E-cadherin {ECO:0000313|EMBL:BAA88957.1};"]
[9990,"'SLC12A6'",382.7,262.12,355,333.273333333333,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00816///Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)+++H01815///Malignant migrating partial seizures in infancy+++H00606///Early infantile epileptic encephalopathy","M00425///H/ACA ribonucleoprotein complex",null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane","GO:0019901///protein kinase binding+++GO:0015377///cation:chloride symporter activity+++GO:0015293///symporter activity+++GO:0015079///potassium ion transmembrane transporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0005215///transporter activity","GO:1902476///chloride transmembrane transport+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0006884///cell volume homeostasis+++GO:0071476///cellular hypotonic response+++GO:0071477///cellular hypotonic salinity response+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0001525///angiogenesis+++GO:0055064///chloride ion homeostasis+++GO:0007268///chemical synaptic transmission+++GO:1990573///potassium ion import across plasma membrane+++GO:0006813///potassium ion transport","solute carrier family 12 member 6","[S12A6_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 6; AltName: Full=Electroneutral potassium-chloride cotransporter 3; AltName: Full=K-Cl cotransporter 3;+++[A0A024R9I5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_d {ECO:0000313|EMBL:EAW92302.1};+++[A0A024R9K8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_a {ECO:0000313|EMBL:EAW92296.1};+++[A7E2U9_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAI50585.1}; Flags: Fragment;+++[B3KXX3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46254 fis, clone TESTI4023096, highly similar to Solute carrier family 12 member 6 {ECO:0000313|EMBL:BAG54635.1};+++[H0YKE6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452771}; Flags: Fragment;+++[H0YKJ2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452828}; Flags: Fragment;+++[H0YKL8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452857}; Flags: Fragment;+++[H0YKQ8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452904};+++[H0YMQ9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_c {ECO:0000313|EMBL:EAW92298.1}; SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000453702};+++[H0YNJ5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000454037}; Flags: Fragment;+++[Q3ZCQ6_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAH51744.1};+++[Q6NSI7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6 {ECO:0000313|EMBL:AAH70107.2};"]
[9991,"'PTBP3'",474,324,336,378,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0030154///cell differentiation+++GO:0043249///erythrocyte maturation+++GO:0006397///mRNA processing+++GO:0033119///negative regulation of RNA splicing+++GO:0008380///RNA splicing+++GO:0045595///regulation of cell differentiation+++GO:0009653///anatomical structure morphogenesis","polypyrimidine tract binding protein 3","[PTBP3_HUMAN|Reviewed]RecName: Full=Polypyrimidine tract-binding protein 3; AltName: Full=Regulator of differentiation 1; Short=Rod1;+++[A0A024R163_HUMAN|Unreviewed]SubName: Full=ROD1 regulator of differentiation 1 (S. pombe), isoform CRA_b {ECO:0000313|EMBL:EAW59101.1};+++[B1ALY4_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000388024}; Flags: Fragment;+++[X6R242_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000210227}; Flags: Fragment;"]
[9992,"'KCNE2'",0,1,0,0.333333333333333,"04971///Gastric acid secretion","H00720///Long QT syndrome+++H00731///Atrial fibrillation",null,null,"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005764///lysosome","GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0015459///potassium channel regulator activity+++GO:0005242///inward rectifier potassium channel activity","GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1902159///regulation of cyclic nucleotide-gated ion channel activity+++GO:0035690///cellular response to drug+++GO:0006813///potassium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086009///membrane repolarization+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0060306///regulation of membrane repolarization+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901979///regulation of inward rectifier potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0034765///regulation of ion transmembrane transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0086011///membrane repolarization during action potential+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:0043586///tongue development+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:0007568///aging+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086091///regulation of heart rate by cardiac conduction","potassium voltage-gated channel subfamily E regulatory subunit 2","[KCNE2_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 2; AltName: Full=MinK-related peptide 1; AltName: Full=Minimum potassium ion channel-related peptide 1; AltName: Full=Potassium channel subunit beta MiRP1;+++[Q2N1I3_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit 2 {ECO:0000313|EMBL:ABB00303.1}; Flags: Fragment;"]
[9993,"'DGCR2'",4996,4804,4862,4887.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0009887///animal organ morphogenesis+++GO:0050890///cognition+++GO:0007155///cell adhesion","DiGeorge syndrome critical region gene 2","[IDD_HUMAN|Reviewed]RecName: Full=Integral membrane protein DGCR2/IDD; Flags: Precursor;+++[B7Z3C4_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2, isoform CRA_c {ECO:0000313|EMBL:EAX03063.1}; SubName: Full=cDNA FLJ50536, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12160.1};+++[B7Z3T5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50553, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12321.1};+++[F6SYP7_HUMAN|Unreviewed]SubName: Full=Integral membrane protein DGCR2/IDD {ECO:0000313|Ensembl:ENSP00000445069};+++[Q5CZ70_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686I1730 {ECO:0000313|EMBL:CAI59783.1};+++[Q8IWC8_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2 {ECO:0000313|EMBL:AAH40500.1};"]
[9994,"'CASP8AP2'",114,69,72,85,"04140///Autophagy - animal+++04137///Mitophagy - animal+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0016605///PML body+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0003714///transcription corepressor activity+++GO:0032184///SUMO polymer binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0002020///protease binding+++GO:0016505///peptidase activator activity involved in apoptotic process+++GO:0005123///death receptor binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0097190///apoptotic signaling pathway+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0036337///Fas signaling pathway+++GO:0006915///apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007049///cell cycle","caspase 8 associated protein 2","[C8AP2_HUMAN|Reviewed]RecName: Full=CASP8-associated protein 2; AltName: Full=FLICE-associated huge protein;+++[A0A087WTW5_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000478179};+++[A0A096LP21_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000485346}; Flags: Fragment;+++[A7E2C0_HUMAN|Unreviewed]SubName: Full=CASP8AP2 protein {ECO:0000313|EMBL:AAI50275.1};+++[L8EC81_HUMAN|Unreviewed]SubName: Full=Alternative protein CASP8AP2 {ECO:0000313|EMBL:CCQ43107.1};"]
[9997,"'SCO2'",138.2,169.54,173,160.246666666667,null,"H01200///Fatal infantile cardioencephalomyopathy+++H02041///Myopia+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005759///mitochondrial matrix+++GO:0030016///myofibril+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane","GO:0005507///copper ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0004645///phosphorylase activity+++GO:0015035///protein disulfide oxidoreductase activity","GO:0045454///cell redox homeostasis+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0006206///pyrimidine nucleobase metabolic process+++GO:0006878///cellular copper ion homeostasis+++GO:0001654///eye development+++GO:0006825///copper ion transport+++GO:0055114///oxidation-reduction process+++GO:0006213///pyrimidine nucleoside metabolic process+++GO:0008535///respiratory chain complex IV assembly","SCO2, cytochrome c oxidase assembly protein","[SCO2_HUMAN|Reviewed]RecName: Full=Protein SCO2 homolog, mitochondrial; Flags: Precursor;+++[A0A1W2PP80_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491034}; Flags: Fragment;+++[A0A1W2PQK0_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491753}; Flags: Fragment;"]

{"sheet":"17 week samples","index":2,"n_rows":16773,"n_cols":15,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["Gene ID","Gene Symbol","17_weeks_1a Read Count","17_weeks_2a Read Count","17_weeks_3a Read Count","17_weeks_a Average Read Count","KEGG Pathway Desc","KEGG Disease Desc","KEGG Module Desc","KEGG Reaction Desc","GO_C Desc","GO_F Desc","GO_P Desc","GeneBank Desc","UniProt Desc"]
[1,"'A1BG'",55,95,144,98,"04380///Osteoclast differentiation",{"$nulls":3},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0031093///platelet alpha granule lumen+++GO:1904813///ficolin-1-rich granule lumen+++GO:0034774///secretory granule lumen+++GO:0062023///collagen-containing extracellular matrix+++GO:0072562///blood microparticle","GO:0003674///molecular_function","GO:0002576///platelet degranulation+++GO:0043312///neutrophil degranulation+++GO:0008150///biological_process","alpha-1-B glycoprotein","[A1BG_HUMAN|Reviewed]RecName: Full=Alpha-1B-glycoprotein; AltName: Full=Alpha-1-B glycoprotein; Flags: Precursor;+++[M0R009_HUMAN|Unreviewed]SubName: Full=Alpha-1B-glycoprotein {ECO:0000313|Ensembl:ENSP00000470909}; Flags: Fragment;+++[V9HWD8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 163pA {ECO:0000313|EMBL:ACJ13639.1};"]
[10,"'NAT2'",1,0,0,0.333333333333333,"00983///Drug metabolism - other enzymes+++05204///Chemical carcinogenesis+++01100///Metabolic pathways+++00633///Nitrotoluene degradation+++00232///Caffeine metabolism+++01110///Biosynthesis of secondary metabolites+++01120///Microbial metabolism in diverse environments",null,null,"R11902///acetyl-CoA:hydrazine N-acetyltransferase   Acetyl-CoA + Hydrazine <=> CoA + Acetylhydrazine+++R07940///1,7-Dimethylxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil+++R08036///acetyl-CoA:2,4-diamino-6-nitrotoluene N-acetyltransferase   2,4-Diamino-6-nitrotoluene + Acetyl-CoA <=> 4-Acetamido-2-amino-6-nitrotoluene + CoA+++R08248///acetyl-CoA: isoniazid N-acetyltransferase   Acetyl-CoA + Isoniazid <=> CoA + N-Acetylisoniazid+++R08250///acetyl-CoA:acetylhydrazine N-acetyltransferase   Acetyl-CoA + Acetylhydrazine <=> CoA + N,N'-Diacetylhydrazine","GO:0005829///cytosol","GO:0004060///arylamine N-acetyltransferase activity","GO:0006805///xenobiotic metabolic process","N-acetyltransferase 2","[ARY2_HUMAN|Reviewed]RecName: Full=Arylamine N-acetyltransferase 2; EC=2.3.1.5; AltName: Full=Arylamide acetylase 2; AltName: Full=N-acetyltransferase type 2; Short=NAT-2; AltName: Full=Polymorphic arylamine N-acetyltransferase; Short=PNAT;+++[A4Z6T7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01136.1};"]
[100,"'ADA'",110,135,141,128.666666666667,"05340///Primary immunodeficiency+++01100///Metabolic pathways+++00230///Purine metabolism","H00092///T-B-Severe combined immunodeficiencies (SCIDs)",null,"R01560///Adenosine aminohydrolase   Adenosine + H2O <=> Inosine + Ammonia+++R02556///Deoxyadenosine aminohydrolase   Deoxyadenosine + H2O <=> Deoxyinosine + Ammonia","GO:0032839///dendrite cytoplasm+++GO:0030054///cell junction+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0060205///cytoplasmic vesicle lumen+++GO:0005764///lysosome+++GO:0005615///extracellular space+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004000///adenosine deaminase activity+++GO:0001883///purine nucleoside binding+++GO:0019239///deaminase activity","GO:0046061///dATP catabolic process+++GO:0042493///response to drug+++GO:0046111///xanthine biosynthetic process+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0043103///hypoxanthine salvage+++GO:0043066///negative regulation of apoptotic process+++GO:0001889///liver development+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0001701///in utero embryonic development+++GO:0032261///purine nucleotide salvage+++GO:0043101///purine-containing compound salvage+++GO:0030324///lung development+++GO:0002314///germinal center B cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0010460///positive regulation of heart rate+++GO:0050870///positive regulation of T cell activation+++GO:0033197///response to vitamin E+++GO:0001821///histamine secretion+++GO:0045580///regulation of T cell differentiation+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0042542///response to hydrogen peroxide+++GO:0060169///negative regulation of adenosine receptor signaling pathway+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007155///cell adhesion+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046101///hypoxanthine biosynthetic process+++GO:0048541///Peyer's patch development+++GO:0001890///placenta development+++GO:0048566///embryonic digestive tract development+++GO:0009117///nucleotide metabolic process+++GO:0060407///negative regulation of penile erection+++GO:0042110///T cell activation+++GO:0070256///negative regulation of mucus secretion+++GO:0042323///negative regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046103///inosine biosynthetic process+++GO:0002636///positive regulation of germinal center formation+++GO:0050728///negative regulation of inflammatory response+++GO:0048286///lung alveolus development+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0046085///adenosine metabolic process+++GO:0002686///negative regulation of leukocyte migration+++GO:0007568///aging+++GO:0043278///response to morphine+++GO:0045582///positive regulation of T cell differentiation+++GO:0001666///response to hypoxia+++GO:0001829///trophectodermal cell differentiation+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process","adenosine deaminase","[ADA_HUMAN|Reviewed]RecName: Full=Adenosine deaminase; EC=3.5.4.4 {ECO:0000269|PubMed:16670267, ECO:0000269|PubMed:23193172, ECO:0000269|PubMed:8452534}; AltName: Full=Adenosine aminohydrolase;+++[A0A0S2Z381_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 1 {ECO:0000313|EMBL:ALQ33350.1}; SubName: Full=Adenosine deaminase, isoform CRA_c {ECO:0000313|EMBL:EAW75906.1}; Flags: Fragment;+++[A0A0S2Z3B9_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 3 {ECO:0000313|EMBL:ALQ33352.1}; Flags: Fragment;+++[A0A0S2Z3T6_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 4 {ECO:0000313|EMBL:ALQ33353.1}; Flags: Fragment;+++[F5GWI4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 2 {ECO:0000313|EMBL:ALQ33351.1};+++[F5GXW0_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000440946};+++[F5GYD4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000446464};+++[Q16073_HUMAN|Unreviewed]SubName: Full=Mutant adenosine deaminase {ECO:0000313|EMBL:AAB28742.2}; Flags: Fragment;+++[X5D767_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform A {ECO:0000313|EMBL:AHW56400.1}; Flags: Fragment;"]
[1000,"'CDH2'",5638,7014,5998,6216.66666666667,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0005788///endoplasmic reticulum lumen+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005911///cell-cell junction+++GO:0016324///apical plasma membrane+++GO:0016342///catenin complex+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0045177///apical part of cell+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0005916///fascia adherens+++GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0042383///sarcolemma+++GO:0030864///cortical actin cytoskeleton+++GO:0044853///plasma membrane raft","GO:0008092///cytoskeletal protein binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding+++GO:0045294///alpha-catenin binding+++GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0060019///radial glial cell differentiation+++GO:0051146///striated muscle cell differentiation+++GO:0007416///synapse assembly+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0072659///protein localization to plasma membrane+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0034332///adherens junction organization+++GO:0048514///blood vessel morphogenesis+++GO:0043410///positive regulation of MAPK cascade+++GO:0060563///neuroepithelial cell differentiation+++GO:0021987///cerebral cortex development+++GO:0010001///glial cell differentiation+++GO:0048854///brain morphogenesis+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050770///regulation of axonogenesis+++GO:1902897///regulation of postsynaptic density protein 95 clustering+++GO:0043687///post-translational protein modification+++GO:0016477///cell migration+++GO:0097150///neuronal stem cell population maintenance+++GO:0048872///homeostasis of number of cells+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0009966///regulation of signal transduction+++GO:0098609///cell-cell adhesion+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0021537///telencephalon development+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0044267///cellular protein metabolic process","cadherin 2","[CADH2_HUMAN|Reviewed]RecName: Full=Cadherin-2; AltName: Full=CDw325; AltName: Full=Neural cadherin; Short=N-cadherin; AltName: CD_antigen=CD325; Flags: Precursor;+++[A0A024RC42_HUMAN|Unreviewed]SubName: Full=Cadherin 2, type 1, N-cadherin (Neuronal), isoform CRA_b {ECO:0000313|EMBL:EAX01241.1};+++[C9J126_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000412120}; Flags: Fragment;+++[C9J8J8_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000411360}; Flags: Fragment;+++[C9JMH2_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000414269}; Flags: Fragment;"]
[10000,"'AKT3'",928,828,714,823.333333333333,"04973///Carbohydrate digestion and absorption+++04150///mTOR signaling pathway+++05211///Renal cell carcinoma+++05230///Central carbon metabolism in cancer+++05221///Acute myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++05145///Toxoplasmosis+++04910///Insulin signaling pathway+++05218///Melanoma+++05166///HTLV-I infection+++04261///Adrenergic signaling in cardiomyocytes+++05164///Influenza A+++04668///TNF signaling pathway+++05210///Colorectal cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05165///Human papillomavirus infection+++04611///Platelet activation+++04722///Neurotrophin signaling pathway+++04071///Sphingolipid signaling pathway+++04212///Longevity regulating pathway - worm+++04371///Apelin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04664///Fc epsilon RI signaling pathway+++05163///Human cytomegalovirus infection+++04024///cAMP signaling pathway+++05226///Gastric cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04550///Signaling pathways regulating pluripotency of stem cells+++04068///FoxO signaling pathway+++04062///Chemokine signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04660///T cell receptor signaling pathway+++04728///Dopaminergic synapse+++04213///Longevity regulating pathway - multiple species+++05160///Hepatitis C+++01524///Platinum drug resistance+++05222///Small cell lung cancer+++04630///Jak-STAT signaling pathway+++04510///Focal adhesion+++05200///Pathways in cancer+++04218///Cellular senescence+++04662///B cell receptor signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04917///Prolactin signaling pathway+++05225///Hepatocellular carcinoma+++05214///Glioma+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++05169///Epstein-Barr virus infection+++05213///Endometrial cancer+++04931///Insulin resistance+++04920///Adipocytokine signaling pathway+++04915///Estrogen signaling pathway+++05161///Hepatitis B+++04066///HIF-1 signaling pathway+++04625///C-type lectin receptor signaling pathway+++05231///Choline metabolism in cancer+++04014///Ras signaling pathway+++05162///Measles+++04151///PI3K-Akt signaling pathway+++04926///Relaxin signaling pathway+++04012///ErbB signaling pathway+++04922///Glucagon signaling pathway+++05224///Breast cancer+++04211///Longevity regulating pathway+++05215///Prostate cancer+++04152///AMPK signaling pathway+++04914///Progesterone-mediated oocyte maturation+++05212///Pancreatic cancer+++04022///cGMP-PKG signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05220///Chronic myeloid leukemia+++04620///Toll-like receptor signaling pathway+++04725///Cholinergic synapse+++04072///Phospholipase D signaling pathway+++04210///Apoptosis+++05152///Tuberculosis+++04140///Autophagy - animal+++05205///Proteoglycans in cancer+++05223///Non-small cell lung cancer+++04370///VEGF signaling pathway+++04919///Thyroid hormone signaling pathway+++04380///Osteoclast differentiation","H01556///Meningioma+++H01222///Cowden syndrome+++H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01909///Hypoinsulinemic hypoglycemia with hemihypertrophy (HIHGHH)+++H00420///Familial partial lipodystrophy (FPL)+++H01649///Schizophrenia+++H00027///Ovarian cancer","M00676///PI3K-Akt signaling",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0035556///intracellular signal transduction+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032008///positive regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0045766///positive regulation of angiogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0045793///positive regulation of cell size+++GO:0000002///mitochondrial genome maintenance+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0048854///brain morphogenesis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0006468///protein phosphorylation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007165///signal transduction+++GO:1905653///positive regulation of artery morphogenesis","AKT serine/threonine kinase 3","[AKT3_HUMAN|Reviewed]RecName: Full=RAC-gamma serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Protein kinase Akt-3; AltName: Full=Protein kinase B gamma; Short=PKB gamma; AltName: Full=RAC-PK-gamma; AltName: Full=STK-2;+++[F8VS91_HUMAN|Unreviewed]SubName: Full=RAC-gamma serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000447820}; Flags: Fragment;+++[Q56A86_HUMAN|Unreviewed]SubName: Full=AKT3 protein {ECO:0000313|EMBL:AAH20479.1}; Flags: Fragment;"]
[10001,"'MED6'",172,184,219.04,191.68,{"$nulls":4},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0000151///ubiquitin ligase complex+++GO:0070847///core mediator complex+++GO:0005654///nucleoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0003712///transcription coregulator activity+++GO:0008134///transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001128///RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance+++GO:0016567///protein ubiquitination","mediator complex subunit 6","[MED6_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6; AltName: Full=Activator-recruited cofactor 33 kDa component; Short=ARC33; AltName: Full=Mediator complex subunit 6; Short=hMed6; AltName: Full=Renal carcinoma antigen NY-REN-28;+++[A0A087WYL7_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};+++[B4DTY4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|RuleBase:RU364143}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|RuleBase:RU364143};+++[G3V4A5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};"]
[10002,"'NR2E3'",1,0,1,0.666666666666667,null,"H00805///Vitreoretinal degeneration+++H02075///Enhanced S-cone syndrome+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0003707///steroid hormone receptor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0008285///negative regulation of cell proliferation+++GO:0007165///signal transduction+++GO:0060041///retina development in camera-type eye+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0050896///response to stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0007601///visual perception+++GO:0042462///eye photoreceptor cell development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045872///positive regulation of rhodopsin gene expression+++GO:0007602///phototransduction+++GO:0006367///transcription initiation from RNA polymerase II promoter","nuclear receptor subfamily 2 group E member 3","[NR2E3_HUMAN|Reviewed]RecName: Full=Photoreceptor-specific nuclear receptor; AltName: Full=Nuclear receptor subfamily 2 group E member 3; AltName: Full=Retina-specific nuclear receptor;+++[F1D8Q9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2, group E, member 3, isoform CRA_b {ECO:0000313|EMBL:EAW77877.1}; SubName: Full=Photoreceptor cell-specific nuclear receptor variant 1 {ECO:0000313|EMBL:ADZ17358.1};+++[Q8IVZ9_HUMAN|Unreviewed]SubName: Full=NR2E3 protein {ECO:0000313|EMBL:AAH41421.1}; SubName: Full=Photoreceptor-specific nuclear receptor {ECO:0000313|Ensembl:ENSP00000479254};+++[Q9UNH8_HUMAN|Unreviewed]SubName: Full=Photoreceptor-specific nuclear receptor {ECO:0000313|EMBL:AAD28302.1}; Flags: Fragment;"]
[10003,"'NAALAD2'",120,71,70,87,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0008236///serine-type peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0016805///dipeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity","GO:0006508///proteolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0042135///neurotransmitter catabolic process+++GO:0008152///metabolic process","N-acetylated alpha-linked acidic dipeptidase 2","[NALD2_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[E9PII2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000431989}; Flags: Fragment;+++[E9PJ53_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435670}; Flags: Fragment;+++[E9PJV2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000433710};+++[E9PKX5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435249};+++[J3KNJ3_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000320083};+++[L8EAF7_HUMAN|Unreviewed]SubName: Full=Alternative protein NAALAD2 {ECO:0000313|EMBL:CCQ43323.1};+++[Q4G181_HUMAN|Unreviewed]SubName: Full=NAALAD2 protein {ECO:0000313|EMBL:AAH27594.1};"]
[100037417,"'DDTL'",11.3,24.07,39.56,24.9766666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0016829///lyase activity",null,"D-dopachrome tautomerase like","[DDTL_HUMAN|Reviewed]RecName: Full=D-dopachrome decarboxylase-like protein; EC=4.1.1.-; AltName: Full=D-dopachrome tautomerase-like protein;+++[A0A0F7RPW6_HUMAN|Unreviewed]SubName: Full=D-dopachrome tautomerase 2 {ECO:0000313|EMBL:CCP37992.1};+++[B5MC82_HUMAN|Unreviewed]SubName: Full=D-dopachrome decarboxylase {ECO:0000313|Ensembl:ENSP00000384866};"]
[10004,"'NAALADL1'",23,18,31,24,{"$nulls":4},"GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004180///carboxypeptidase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity","GO:0008152///metabolic process+++GO:0006508///proteolysis","N-acetylated alpha-linked acidic dipeptidase like 1","[NALDL_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein; Short=NAALADase L; EC=3.4.17.21; AltName: Full=100 kDa ileum brush border membrane protein; Short=I100; AltName: Full=Ileal dipeptidylpeptidase;+++[C9JFW8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000349045};+++[E9PII9_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431977};+++[E9PIU1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433892}; Flags: Fragment;+++[E9PJQ1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435549}; Flags: Fragment;+++[E9PKG8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433538}; Flags: Fragment;+++[E9PKR0_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431513};+++[E9PKW7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435267}; Flags: Fragment;+++[E9PLR8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431322}; Flags: Fragment;+++[E9PRC7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434233}; Flags: Fragment;+++[H0YDS5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434225}; Flags: Fragment;+++[H0YEI8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435917}; Flags: Fragment;"]
[100049587,"'SIGLEC14'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0101003///ficolin-1-rich granule membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane","GO:0030246///carbohydrate binding","GO:0043312///neutrophil degranulation+++GO:0007155///cell adhesion+++GO:0045087///innate immune response","sialic acid binding Ig like lectin 14","[SIG14_HUMAN|Reviewed]RecName: Full=Sialic acid-binding Ig-like lectin 14; Short=Siglec-14; Flags: Precursor;"]
[10005,"'ACOT8'",353,320,407,360,"00120///Primary bile acid biosynthesis+++01100///Metabolic pathways+++04146///Peroxisome",null,"M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R03974///chenodeoxycholoyl-CoA hydrolase   Chenodeoxycholate + CoA <=> Chenodeoxycholoyl-CoA + H2O+++R07296///choloyl-CoA hydrolase   Choloyl-CoA + H2O <=> Cholic acid + CoA","GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol","GO:0052815///medium-chain acyl-CoA hydrolase activity+++GO:0005102///signaling receptor binding+++GO:0052816///long-chain acyl-CoA hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0033882///choloyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0003986///acetyl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016289///CoA hydrolase activity","GO:0043649///dicarboxylic acid catabolic process+++GO:0007031///peroxisome organization+++GO:0045225///negative regulation of CD4 biosynthetic process+++GO:0016032///viral process+++GO:0006637///acyl-CoA metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0016559///peroxisome fission+++GO:0036109///alpha-linolenic acid metabolic process","acyl-CoA thioesterase 8","[ACOT8_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A thioesterase 8; Short=Acyl-CoA thioesterase 8; EC=3.1.2.27 {ECO:0000269|PubMed:15194431, ECO:0000269|PubMed:9299485}; AltName: Full=Choloyl-coenzyme A thioesterase; AltName: Full=HIV-Nef-associated acyl-CoA thioesterase; AltName: Full=PTE-2; AltName: Full=Peroxisomal acyl-coenzyme A thioester hydrolase 1; Short=PTE-1; AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase 1; AltName: Full=Thioesterase II; Short=hACTE-III; Short=hACTEIII; Short=hTE;+++[E9PIS4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000433923};+++[E9PJN0_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435581};+++[E9PMC4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000431175};+++[E9PRD4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000434216};+++[F6VBM3_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435115};+++[H0Y698_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000403862}; Flags: Fragment;+++[H7C5A7_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000419403}; Flags: Fragment;+++[Q6FHI2_HUMAN|Unreviewed]SubName: Full=PTE1 protein {ECO:0000313|EMBL:CAG46570.1};+++[Q9BR14_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000416217}; Flags: Fragment;"]
[10006,"'ABI1'",1935,2023,1663,1873.66666666667,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0005783///endoplasmic reticulum+++GO:0031252///cell leading edge+++GO:0005634///nucleus+++GO:0031209///SCAR complex+++GO:0014069///postsynaptic density+++GO:0030426///growth cone+++GO:0032433///filopodium tip+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0030175///filopodium+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005856///cytoskeleton","GO:0030296///protein tyrosine kinase activator activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0017124///SH3 domain binding+++GO:0045296///cadherin binding","GO:0048813///dendrite morphogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0072673///lamellipodium morphogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0016032///viral process+++GO:0035855///megakaryocyte development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001756///somitogenesis+++GO:0008154///actin polymerization or depolymerization","abl interactor 1","[ABI1_HUMAN|Reviewed]RecName: Full=Abl interactor 1; AltName: Full=Abelson interactor 1; Short=Abi-1; AltName: Full=Abl-binding protein 4; Short=AblBP4; AltName: Full=Eps8 SH3 domain-binding protein; Short=Eps8-binding protein; AltName: Full=Nap1-binding protein; Short=Nap1BP; AltName: Full=Spectrin SH3 domain-binding protein 1; AltName: Full=e3B1;+++[A0A0A0MRT6_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000365330};+++[B6VEX3_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 41 {ECO:0000313|EMBL:ACJ12783.1};+++[B6VEX4_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000439646}; SubName: Full=Abl-interactor 1 variant 21 {ECO:0000313|EMBL:ACJ12784.1};+++[B6VEX5_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 72 {ECO:0000313|EMBL:ACJ12785.1};+++[L8EC66_HUMAN|Unreviewed]SubName: Full=Alternative protein ABI1 {ECO:0000313|EMBL:CCQ43032.1};"]
[10007,"'GNPDA1'",888,956,881,908.333333333333,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways",null,null,"R00765///D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); D-glucosamine-6-phosphate   D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia","GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0043209///myelin sheath+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0060170///ciliary membrane+++GO:0034774///secretory granule lumen","GO:0016853///isomerase activity+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0004347///glucose-6-phosphate isomerase activity+++GO:0016787///hydrolase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0048029///monosaccharide binding+++GO:0042802///identical protein binding+++GO:0004342///glucosamine-6-phosphate deaminase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0016866///intramolecular transferase activity+++GO:0008134///transcription factor binding+++GO:0004672///protein kinase activity+++GO:0004707///MAP kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding","GO:0051156///glucose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0006094///gluconeogenesis+++GO:0016310///phosphorylation+++GO:0033574///response to testosterone+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0006043///glucosamine catabolic process+++GO:0032570///response to progesterone+++GO:0035556///intracellular signal transduction+++GO:0001707///mesoderm formation+++GO:0007338///single fertilization+++GO:0016055///Wnt signaling pathway+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0035902///response to immobilization stress+++GO:0042501///serine phosphorylation of STAT protein+++GO:0010595///positive regulation of endothelial cell migration+++GO:0035994///response to muscle stretch+++GO:0061621///canonical glycolysis+++GO:0043312///neutrophil degranulation+++GO:0005975///carbohydrate metabolic process+++GO:0046777///protein autophosphorylation+++GO:0007599///hemostasis+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0010469///regulation of signaling receptor activity+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0000165///MAPK cascade+++GO:0050821///protein stabilization+++GO:0001701///in utero embryonic development+++GO:0046185///aldehyde catabolic process+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0046686///response to cadmium ion+++GO:0042593///glucose homeostasis+++GO:0019242///methylglyoxal biosynthetic process+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0043278///response to morphine+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006959///humoral immune response+++GO:0032355///response to estradiol+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010468///regulation of gene expression+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0007611///learning or memory+++GO:0006468///protein phosphorylation+++GO:0034101///erythrocyte homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006046///N-acetylglucosamine catabolic process","glucosamine-6-phosphate deaminase 1","[GNPI1_HUMAN|Reviewed]RecName: Full=Glucosamine-6-phosphate isomerase 1; EC=3.5.99.6; AltName: Full=Glucosamine-6-phosphate deaminase 1; Short=GNPDA 1; Short=GlcN6P deaminase 1; AltName: Full=Oscillin;+++[A0A0A0MTS2_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0G2JLI6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464798}; Flags: Fragment;+++[A0A0J9YX90_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488295}; Flags: Fragment;+++[A0A0J9YXH9_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488409}; Flags: Fragment;+++[A0A0J9YXM3_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488465}; Flags: Fragment;+++[A0A0J9YXP8_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYH3_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYI8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488871}; Flags: Fragment;+++[A0A2R8Y6C7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000495129};+++[A0A2R8YF08_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000496041}; Flags: Fragment;+++[D6R917_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000422173}; Flags: Fragment;+++[D6R9P4_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197};+++[D6RAY7_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RB13_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFF8_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFK5_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000426583}; Flags: Fragment;+++[K7EIL4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464797}; Flags: Fragment;+++[K7ELR7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466191}; Flags: Fragment;+++[K7ENA0_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466851}; Flags: Fragment;+++[K7EP41_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467221}; Flags: Fragment;+++[K7EPY4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467590}; Flags: Fragment;+++[K7EQ48_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[K7ERC6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468201}; Flags: Fragment;+++[K7ERK8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468298}; Flags: Fragment;"]
[10008,"'KCNE3'",71,57,74,67.3333333333333,"04974///Protein digestion and absorption","H00728///Brugada syndrome (BRS)+++H00215///Periodic paralysis",null,null,"GO:0031982///vesicle+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0008076///voltage-gated potassium channel complex+++GO:0005886///plasma membrane+++GO:0043204///perikaryon+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0032809///neuronal cell body membrane","GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005515///protein binding+++GO:0005244///voltage-gated ion channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity","GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:0006813///potassium ion transport+++GO:1905025///negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0006811///ion transport+++GO:0043266///regulation of potassium ion transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:1902260///negative regulation of delayed rectifier potassium channel activity","potassium voltage-gated channel subfamily E regulatory subunit 3","[KCNE3_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 3; AltName: Full=MinK-related peptide 2; AltName: Full=Minimum potassium ion channel-related peptide 2; AltName: Full=Potassium channel subunit beta MiRP2;+++[E9PJQ7_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000435539}; Flags: Fragment;+++[E9PJV9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000433697}; Flags: Fragment;+++[E9PN03_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000434890}; Flags: Fragment;+++[Q2N1I1_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3a {ECO:0000313|EMBL:ABB00304.1}; SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3b {ECO:0000313|EMBL:ABB00305.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000431739}; Flags: Fragment;+++[Q6IAE6_HUMAN|Unreviewed]SubName: Full=KCNE3 protein {ECO:0000313|EMBL:CAG33490.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|EMBL:ABQ01240.1}; SubName: Full=Potassium voltage-gated channel, Isk-related family, member 3 {ECO:0000313|EMBL:AAI10613.1}; SubName: Full=cDNA, FLJ92142, Homo sapiens potassium voltage-gated channel, Isk-related family,member 3 (KCNE3), mRNA {ECO:0000313|EMBL:BAG34817.1};"]
[10009,"'ZBTB33'",411,403,381,398.333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0003677///DNA binding+++GO:0008327///methyl-CpG binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035556///intracellular signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway","zinc finger and BTB domain containing 33","[KAISO_HUMAN|Reviewed]RecName: Full=Transcriptional regulator Kaiso; AltName: Full=Zinc finger and BTB domain-containing protein 33;+++[L8E7W8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZBTB33 {ECO:0000313|EMBL:CCQ43375.1};"]
[1001,"'CDH3'",10514,10712,10416,10547.3333333333,"04514///Cell adhesion molecules (CAMs)","H00785///Congenital hypotrichosis with juvenile macular dystrophy+++H00639///Ectodermal dysplasia, ectrodactyly, and macular dystrophy (EEM syndrome)",null,null,"GO:0005913///cell-cell adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0098794///postsynapse+++GO:0005802///trans-Golgi network+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0030027///lamellipodium+++GO:0016328///lateral plasma membrane+++GO:0016600///flotillin complex+++GO:0005768///endosome+++GO:0043296///apical junction complex+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane","GO:0030506///ankyrin binding+++GO:0042802///identical protein binding+++GO:0032794///GTPase activating protein binding+++GO:0045295///gamma-catenin binding+++GO:0005509///calcium ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0045296///cadherin binding+++GO:0008013///beta-catenin binding","GO:0035635///entry of bacterium into host cell+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0072659///protein localization to plasma membrane+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0009636///response to toxic substance+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0022405///hair cycle process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0051796///negative regulation of timing of catagen+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0098609///cell-cell adhesion+++GO:0071681///cellular response to indole-3-methanol+++GO:0031424///keratinization+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0010628///positive regulation of gene expression+++GO:0001895///retina homeostasis+++GO:0042060///wound healing+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0071285///cellular response to lithium ion+++GO:1902910///positive regulation of melanosome transport+++GO:0031175///neuron projection development+++GO:0007601///visual perception+++GO:0007155///cell adhesion","cadherin 3","[CADH3_HUMAN|Reviewed]RecName: Full=Cadherin-3; AltName: Full=Placental cadherin; Short=P-cadherin; Flags: Precursor;+++[B4DLF0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50795, highly similar to Cadherin-3 {ECO:0000313|EMBL:BAG59512.1};"]
[10010,"'TANK'",318,278,270,288.666666666667,"04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway",{"$nulls":3},"GO:0035631///CD40 receptor complex+++GO:0097057///TRAF2-GSTP1 complex+++GO:0005654///nucleoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0045121///membrane raft+++GO:1990604///IRE1-TRAF2-ASK1 complex+++GO:0012506///vesicle membrane+++GO:0000151///ubiquitin ligase complex+++GO:0005938///cell cortex+++GO:1990597///AIP1-IRE1 complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex","GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0019899///enzyme binding+++GO:0046625///sphingolipid binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005174///CD40 receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035800///deubiquitinase activator activity+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0031996///thioesterase binding+++GO:0008289///lipid binding","GO:0070207///protein homotrimerization+++GO:0051291///protein heterooligomerization+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:0016579///protein deubiquitination+++GO:0007165///signal transduction+++GO:0006915///apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:2000158///positive regulation of ubiquitin-specific protease activity+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016032///viral process+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0032743///positive regulation of interleukin-2 production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0065003///protein-containing complex assembly+++GO:0070534///protein K63-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0071479///cellular response to ionizing radiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0090073///positive regulation of protein homodimerization activity+++GO:0071550///death-inducing signaling complex assembly+++GO:0043507///positive regulation of JUN kinase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1901215///negative regulation of neuron death+++GO:0051865///protein autoubiquitination+++GO:0097300///programmed necrotic cell death+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0034976///response to endoplasmic reticulum stress+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0051023///regulation of immunoglobulin secretion+++GO:0071347///cellular response to interleukin-1+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0046328///regulation of JNK cascade+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0006508///proteolysis+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030163///protein catabolic process+++GO:0034622///cellular protein-containing complex assembly+++GO:0071356///cellular response to tumor necrosis factor+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0034351///negative regulation of glial cell apoptotic process","TRAF family member associated NFKB activator","[TANK_HUMAN|Reviewed]RecName: Full=TRAF family member-associated NF-kappa-B activator; AltName: Full=TRAF-interacting protein; Short=I-TRAF;+++[B1AMX7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000405860}; Flags: Fragment;+++[B1AMX8_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000406524}; Flags: Fragment;+++[B1AMY1_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000397653}; Flags: Fragment;+++[B2R7S3_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93580, highly similar to Homo sapiens TRAF family member-associated NFKB activator (TANK), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG35920.1};+++[E5KBQ3_HUMAN|Unreviewed]SubName: Full=TRAF2 {ECO:0000313|EMBL:ADQ89802.1};+++[E7EM55_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412622};+++[E7EMT6_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000392776}; Flags: Fragment;+++[E7ENY2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000411041}; Flags: Fragment;+++[E7EQA9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000385487};+++[E7ERM9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000388930};+++[E7EV32_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000398157}; Flags: Fragment;+++[E7EVA2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384492};+++[E7EW82_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384235};+++[E7EWR8_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000399934}; Flags: Fragment;+++[E9PEK1_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000410259};+++[H7BZ28_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000387439}; Flags: Fragment;+++[H7C3L4_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412556}; Flags: Fragment;+++[Q4ZG76_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAX88939.1}; Flags: Fragment;+++[Q53TI5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAY14785.1}; Flags: Fragment;+++[Q6NW12_HUMAN|Unreviewed]SubName: Full=TANK protein {ECO:0000313|EMBL:AAH67779.1};"]
[100101267,"'POM121C'",3514.51,3306.01,2565.29,3128.60333333333,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005515///protein binding+++GO:0035804///structural constituent of egg coat+++GO:0017056///structural constituent of nuclear pore+++GO:0003676///nucleic acid binding+++GO:0008139///nuclear localization sequence binding","GO:0007339///binding of sperm to zona pellucida+++GO:0035803///egg coat formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016032///viral process+++GO:0051028///mRNA transport+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus","POM121 transmembrane nucleoporin C","[P121C_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[A1L4L9_HUMAN|Unreviewed]SubName: Full=POM121C protein {ECO:0000313|EMBL:AAI30588.1};+++[A8MY32_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000381415}; Flags: Fragment;+++[B4DDR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56876, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG56826.1};+++[B4DET5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG57196.1};+++[C9JFL1_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000410033}; Flags: Fragment;"]
[100101467,"'ZSCAN30'",225,238,188,217,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated","zinc finger and SCAN domain containing 30","[ZSC30_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 30; AltName: Full=ZNF-WYM; AltName: Full=Zinc finger protein 397 opposite strand; AltName: Full=Zinc finger protein 397OS;+++[A0A0C4DGV0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000480152};+++[A0A1W2PP20_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000491237};+++[C9JCM2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000465046};+++[K7EPB0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000467308}; Flags: Fragment;+++[K7ERA9_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000468180}; Flags: Fragment;+++[M0QZC3_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470443};+++[M0QZP2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470677}; Flags: Fragment;+++[M0R1Y0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000472179};"]
[10011,"'SRA1'",518,591,697,602,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge","GO:0003713///transcription coactivator activity+++GO:0002153///steroid receptor RNA activator RNA binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:2000273///positive regulation of signaling receptor activity+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0006351///transcription, DNA-templated+++GO:0071391///cellular response to estrogen stimulus","steroid receptor RNA activator 1","[SRA1_HUMAN|Reviewed]RecName: Full=Steroid receptor RNA activator 1; AltName: Full=Steroid receptor RNA activator protein; Short=SRAP;"]
[100113407,"'TMEM170B'",141,108,81,110,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway","transmembrane protein 170B","[T170B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 170B;"]
[100125288,"'ZGLP1'",33,23,44,33.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0048599///oocyte development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis","zinc finger, GATA-like protein 1","[ZGLP1_HUMAN|Reviewed]RecName: Full=GATA-type zinc finger protein 1; AltName: Full=GATA-like protein 1; Short=GLP-1;+++[B5MCP8_HUMAN|Unreviewed]SubName: Full=GATA-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000385403};"]
[100127983,"'C8orf88'",307,253,242,267.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0008190///eukaryotic initiation factor 4E binding","GO:0045947///negative regulation of translational initiation","chromosome 8 open reading frame 88","[CH088_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C8orf88;"]
[100128071,"'FAM229A'",35,39,55,43,{"$nulls":7},"family with sequence similarity 229 member A","[F229A_HUMAN|Reviewed]RecName: Full=Protein FAM229A;+++[H3BMD6_HUMAN|Unreviewed]SubName: Full=Protein FAM229A {ECO:0000313|Ensembl:ENSP00000454338}; Flags: Fragment;"]
[100128108,"'LOC100128108'",7,3,8,6,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"putative ubiquitin-conjugating enzyme E2Q2-like protein","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;+++[UB2Q2_BOVIN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_HUMAN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_MOUSE|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_RABIT|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-conjugating enzyme UBCi; AltName: Full=Ubiquitin-protein ligase Q2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100128242,"'LOC100128242'",25,9.23,13,15.7433333333333,{"$nulls":7},"uncharacterized LOC100128242","[A0A1B0GVV0_HUMAN|diamond]SubName: Full=GRAM domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000490665};+++[A0A2I3SSV7_PANTR|diamond]SubName: Full=GRAM domain containing 1B {ECO:0000313|Ensembl:ENSPTRP00000080022};+++[A0A2J8N1X4_PANTR|diamond]SubName: Full=GRAMD1B isoform 18 {ECO:0000313|EMBL:PNI65769.1};+++[A0A2J8X087_PONAB|diamond]SubName: Full=GRAMD1B isoform 17 {ECO:0000313|EMBL:PNJ75447.1};+++[A0A2R9B6E3_PANPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000024636};"]
[100128327,"'TRAPPC3L'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0030008///TRAPP complex+++GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0033106///cis-Golgi network membrane","GO:0005515///protein binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0048193///Golgi vesicle transport+++GO:0008150///biological_process+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport","trafficking protein particle complex 3 like","[TPC3L_HUMAN|Reviewed]RecName: Full=Trafficking protein particle complex subunit 3-like protein; Short=TRAPPC3-like protein; AltName: Full=BET3-like protein;+++[A0A0A0MSL6_HUMAN|Unreviewed]SubName: Full=Trafficking protein particle complex subunit 3-like protein {ECO:0000313|Ensembl:ENSP00000395769}; Flags: Fragment;"]
[100128553,"'CTAGE4'",47.44,59.42,51.38,52.7466666666667,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0042954///lipoprotein transporter activity","GO:0042953///lipoprotein transport+++GO:0008150///biological_process+++GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion","CTAGE family member 4","[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[A0A2R8Y569_HUMAN|Unreviewed]SubName: Full=cTAGE family member 4 {ECO:0000313|Ensembl:ENSP00000494570};"]
[100128569,"'C19orf71'",0,3,0,1,{"$nulls":7},"chromosome 19 open reading frame 71","[CS071_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf71;"]
[100128731,"'OST4'",1099,1235,1594,1309.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0015631///tubulin binding+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding","GO:0018279///protein N-linked glycosylation via asparagine+++GO:0006486///protein glycosylation","oligosaccharyltransferase complex subunit 4, non-catalytic","[OST4_HUMAN|Reviewed]RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4;"]
[100128927,"'ZBTB42'",74,97,111,94,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0007517///muscle organ development+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 42","[ZBT42_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 42;"]
[100129083,"'LOC100129083'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane","GO:0030246///carbohydrate binding+++GO:0042169///SH2 domain binding+++GO:0019902///phosphatase binding","GO:0007155///cell adhesion+++GO:0002250///adaptive immune response+++GO:0106015///negative regulation of inflammatory response to wounding+++GO:0045087///innate immune response","uncharacterized LOC100129083","[CD33_HUMAN|diamond]RecName: Full=Myeloid cell surface antigen CD33; AltName: Full=Sialic acid-binding Ig-like lectin 3; Short=Siglec-3; AltName: Full=gp67; AltName: CD_antigen=CD33; Flags: Precursor;+++[SIG10_HUMAN|diamond]RecName: Full=Sialic acid-binding Ig-like lectin 10; Short=Siglec-10; AltName: Full=Siglec-like protein 2; Flags: Precursor;+++[SIG11_HUMAN|diamond]RecName: Full=Sialic acid-binding Ig-like lectin 11; Short=Sialic acid-binding lectin 11; Short=Siglec-11; Flags: Precursor;+++[SIG16_HUMAN|diamond]RecName: Full=Sialic acid-binding Ig-like lectin 16; Short=Siglec-16; AltName: Full=Siglec-P16; Flags: Precursor;+++[SIGL8_HUMAN|diamond]RecName: Full=Sialic acid-binding Ig-like lectin 8; Short=Siglec-8; AltName: Full=Sialoadhesin family member 2; Short=SAF-2; Flags: Precursor;"]
[100129098,"'LOC100129098'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0044798///nuclear transcription factor complex","GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003705///transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding+++GO:0008013///beta-catenin binding+++GO:0043565///sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0072001///renal system development+++GO:0042789///mRNA transcription by RNA polymerase II+++GO:0060913///cardiac cell fate determination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060807///regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification+++GO:0045597///positive regulation of cell differentiation+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0048866///stem cell fate specification+++GO:0035050///embryonic heart tube development+++GO:0031648///protein destabilization+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0061009///common bile duct development+++GO:0050821///protein stabilization+++GO:0001706///endoderm formation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0001570///vasculogenesis+++GO:2000035///regulation of stem cell division+++GO:0030308///negative regulation of cell growth+++GO:0003142///cardiogenic plate morphogenesis+++GO:0003143///embryonic heart tube morphogenesis+++GO:0060214///endocardium formation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0003151///outflow tract morphogenesis+++GO:0060956///endocardial cell differentiation+++GO:0072091///regulation of stem cell proliferation+++GO:0007493///endodermal cell fate determination+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060914///heart formation+++GO:0048617///embryonic foregut morphogenesis+++GO:0045995///regulation of embryonic development+++GO:0001828///inner cell mass cellular morphogenesis+++GO:0061010///gall bladder development+++GO:0001947///heart looping+++GO:0003308///negative regulation of Wnt signaling pathway involved in heart development+++GO:0060070///canonical Wnt signaling pathway+++GO:0042662///negative regulation of mesodermal cell fate specification+++GO:0042074///cell migration involved in gastrulation+++GO:0061031///endodermal digestive tract morphogenesis+++GO:2000043///regulation of cardiac cell fate specification+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0045732///positive regulation of protein catabolic process+++GO:0001525///angiogenesis+++GO:0021903///rostrocaudal neural tube patterning","translation initiation factor IF-2","[S17AA_XENLA|diamond]RecName: Full=Transcription factor Sox-17-alpha-A; Short=Xsox17alpha {ECO:0000312|EMBL:AAI06404.1}; Short=xSox17alpha1 {ECO:0000312|EMBL:BAB60827.1};+++[S17AB_XENLA|diamond]RecName: Full=Transcription factor Sox-17-alpha-B; Short=xSox17alpha2 {ECO:0000312|EMBL:BAB60828.1};+++[SOX17_HUMAN|diamond]RecName: Full=Transcription factor SOX-17;+++[SOX17_MOUSE|diamond]RecName: Full=Transcription factor SOX-17;+++[SX17A_XENTR|diamond]RecName: Full=Transcription factor Sox-17-alpha {ECO:0000250|UniProtKB:Q3KQ35}; Short=Sox17alpha {ECO:0000312|EMBL:AAT71996.1}; Short=tSox17alpha {ECO:0000303|PubMed:12508233};"]
[100129128,"'KHDC1L'",1,0,0,0.333333333333333,{"$nulls":5},"GO:0003723///RNA binding",null,"KH domain containing 1 like","[KHDCL_HUMAN|Reviewed]RecName: Full=Putative KHDC1-like protein;"]
[100129250,"'SMIM27'",40,32,50,40.6666666666667,"05016///Huntington's disease+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++05012///Parkinson's disease+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)",null,"M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly","small integral membrane protein 27","[SIM27_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 27 {ECO:0000305}; AltName: Full=TOPORS antisense RNA 1 {ECO:0000305};+++[A0A1B0GV65_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490387};+++[A0A1B0GW09_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490727}; Flags: Fragment;+++[A0A1W2PRY6_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000492552}; Flags: Fragment;+++[A0A286YEC1_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000414891};+++[A0A2R8Y3B0_HUMAN|Unreviewed]SubName: Full=HCG1811779, isoform CRA_a {ECO:0000313|EMBL:EAW58544.1}; SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000493510};"]
[100129361,"'SMIM10L1'",581,601,584,588.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"small integral membrane protein 10 like 1","[SIML1_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 1 {ECO:0000305};"]
[100129396,"'FAM106CP'",5.7,2,2.25,3.31666666666667,{"$nulls":7},"family with sequence similarity 106 member C, pseudogene","[F106C_HUMAN|Reviewed]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;"]
[100129480,"'MKRN2OS'",3.08,7.04,5,5.04,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"MKRN2 opposite strand","[MKROS_HUMAN|Reviewed]RecName: Full=MKRN2 opposite strand protein; AltName: Full=MKRN2 antisense RNA 1; AltName: Full=MKRN2 antisense gene protein 1;+++[H3BSJ0_HUMAN|Unreviewed]SubName: Full=MKRN2 opposite strand protein {ECO:0000313|Ensembl:ENSP00000456723};"]
[100129484,"'LOC100129484'",18,14,18,16.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100129484","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100129528,"'MUC8'",0,0,2,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component",null,"GO:0008150///biological_process","mucin 8","[Q12964_HUMAN|Unreviewed]SubName: Full=Mucin {ECO:0000313|EMBL:AAA58346.1}; Flags: Fragment;"]
[100129543,"'ZNF730'",34,23,12,23,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 730","[ZN730_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 730;+++[M0QYG2_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469805}; Flags: Fragment;+++[M0QYI4_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469853};"]
[100129583,"'FAM47E'",14.32,8.49,8.35,10.3866666666667,{"$nulls":4},"GO:0005737///cytoplasm","GO:0003674///molecular_function","GO:0008150///biological_process","family with sequence similarity 47 member E","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[A0A1B0GTQ8_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000489801};+++[A0A1B0GUL4_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000490159};+++[D6RBT2_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000422559}; Flags: Fragment;+++[U3KQR7_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000476166}; Flags: Fragment;"]
[100129654,"'TCF24'",0,0,2,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046983///protein dimerization activity+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","transcription factor 24","[TCF24_HUMAN|Reviewed]RecName: Full=Transcription factor 24; Short=TCF-24;"]
[100129792,"'CCDC152'",49,33,36,39.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031089///platelet dense granule lumen+++GO:0005576///extracellular region","GO:0008430///selenium binding","GO:0019953///sexual reproduction+++GO:0001887///selenium compound metabolic process+++GO:0007626///locomotory behavior+++GO:0002576///platelet degranulation+++GO:0009791///post-embryonic development+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0040008///regulation of growth","coiled-coil domain containing 152","[CC152_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 152;+++[A0A024R043_HUMAN|Unreviewed]SubName: Full=HCG2006161, isoform CRA_a {ECO:0000313|EMBL:EAW56025.1};+++[L0R835_HUMAN|Unreviewed]SubName: Full=Alternative protein CCDC152 {ECO:0000313|EMBL:CCO13701.1};"]
[100129842,"'ZNF737'",200,178,206,194.666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 737","[ZN737_HUMAN|Reviewed]RecName: Full=Zinc finger protein 737; AltName: Full=Zinc finger protein 102;+++[M0QZS4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000470737};+++[M0R1D1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471784}; Flags: Fragment;+++[M0R1M3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471973};+++[M0R1M8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471995}; Flags: Fragment;"]
[100129924,"'TMEM269'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 269","[TM269_HUMAN|Reviewed]RecName: Full=Transmembrane protein 269 {ECO:0000312|HGNC:HGNC:52381};+++[A0A1B0GUR4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 269 {ECO:0000313|Ensembl:ENSP00000490213};"]
[100129940,"'LOC100129940'",5,4,0,3,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030686///90S preribosome","GO:0043236///laminin binding+++GO:0043022///ribosome binding+++GO:0003723///RNA binding+++GO:0005055///laminin receptor activity+++GO:0001618///virus receptor activity+++GO:0003735///structural constituent of ribosome","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000028///ribosomal small subunit assembly+++GO:0007155///cell adhesion+++GO:0006412///translation+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006413///translational initiation+++GO:0000461///endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006407///rRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","uncharacterized LOC100129940","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RSSA_BOVIN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Protein C10;+++[RSSA_CHLAE|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_HUMAN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Colon carcinoma laminin-binding protein; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Multidrug resistance-associated protein MGr1-Ag; AltName: Full=NEM/1CHD4; AltName: Full=Small ribosomal subunit protein uS2 {ECO:0000303|PubMed:24524803};+++[RSSA_PIG|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_SHEEP|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10013,"'HDAC6'",883,943,945,923.666666666667,"05034///Alcoholism+++05203///Viral carcinogenesis+++05165///Human papillomavirus infection",{"$nulls":3},"GO:0016235///aggresome+++GO:0005874///microtubule+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm+++GO:0016234///inclusion body+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0030286///dynein complex+++GO:0005654///nucleoplasm+++GO:0005771///multivesicular body+++GO:0031252///cell leading edge+++GO:0005875///microtubule associated complex+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005881///cytoplasmic microtubule+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005901///caveola+++GO:0044297///cell body+++GO:0043204///perikaryon+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0008013///beta-catenin binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0048156///tau protein binding+++GO:0043130///ubiquitin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004407///histone deacetylase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0070840///dynein complex binding+++GO:0003779///actin binding+++GO:0042903///tubulin deacetylase activity+++GO:0051787///misfolded protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0051879///Hsp90 protein binding+++GO:0042826///histone deacetylase binding+++GO:0048487///beta-tubulin binding+++GO:0008017///microtubule binding+++GO:0043014///alpha-tubulin binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)","GO:0006886///intracellular protein transport+++GO:0031647///regulation of protein stability+++GO:0060997///dendritic spine morphogenesis+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0048668///collateral sprouting+++GO:0051788///response to misfolded protein+++GO:0070848///response to growth factor+++GO:0032984///protein-containing complex disassembly+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0009967///positive regulation of signal transduction+++GO:0000209///protein polyubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0035967///cellular response to topologically incorrect protein+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0051646///mitochondrion localization+++GO:0060271///cilium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0032461///positive regulation of protein oligomerization+++GO:0045861///negative regulation of proteolysis+++GO:0045598///regulation of fat cell differentiation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0070846///Hsp90 deacetylation+++GO:0009636///response to toxic substance+++GO:0006325///chromatin organization+++GO:0032418///lysosome localization+++GO:0010033///response to organic substance+++GO:0010727///negative regulation of hydrogen peroxide metabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016241///regulation of macroautophagy+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006914///autophagy+++GO:0043242///negative regulation of protein complex disassembly+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:0090042///tubulin deacetylation+++GO:0010506///regulation of autophagy+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0060632///regulation of microtubule-based movement+++GO:0006476///protein deacetylation+++GO:0070201///regulation of establishment of protein localization+++GO:0070842///aggresome assembly+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070845///polyubiquitinated misfolded protein transport+++GO:0010469///regulation of signaling receptor activity+++GO:0070932///histone H3 deacetylation+++GO:0016575///histone deacetylation+++GO:0010634///positive regulation of epithelial cell migration+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0060765///regulation of androgen receptor signaling pathway","histone deacetylase 6","[HDAC6_HUMAN|Reviewed]RecName: Full=Histone deacetylase 6; Short=HD6; EC=3.5.1.98;+++[A0A024QZ26_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8Y4G2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494007}; Flags: Fragment;+++[A0A2R8Y559_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494293}; Flags: Fragment;+++[A0A2R8Y5Z4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495151};+++[A0A2R8Y6Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495932}; Flags: Fragment;+++[A0A2R8Y758_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000496032}; Flags: Fragment;+++[A0A2R8YCS4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000493921}; Flags: Fragment;+++[A0A2R8YD35_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494230}; Flags: Fragment;+++[A0A2R8YDE6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8YGC5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495872}; Flags: Fragment;+++[A6NDI8_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000365831}; Flags: Fragment;+++[B4DZH6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[C9J172_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000392815}; Flags: Fragment;+++[C9JEF4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000403370}; Flags: Fragment;+++[E7EP63_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402751}; Flags: Fragment;+++[E7EPS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402189}; Flags: Fragment;+++[E7ER52_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000394377}; Flags: Fragment;+++[H7C0Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000397697}; Flags: Fragment;+++[Q9BRX7_HUMAN|Unreviewed]SubName: Full=HDAC6 protein {ECO:0000313|EMBL:AAH05872.1}; SubName: Full=Histone deacetylase 6 {ECO:0000313|EMBL:AAP35295.1, ECO:0000313|Ensembl:ENSP00000393916};+++[Q9NSW6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};"]
[100130301,"'C8orf89'",0,0,1,0.333333333333333,{"$nulls":7},"chromosome 8 open reading frame 89","[CH089_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C8orf89 {ECO:0000305};+++[A0A087WUN2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C8orf89 {ECO:0000313|Ensembl:ENSP00000478788};+++[A0A096LNS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C8orf89 {ECO:0000313|Ensembl:ENSP00000485199};"]
[100130311,"'C17orf107'",319,232,211,254,"04080///Neuroactive ligand-receptor interaction","H00770///Congenital myasthenic syndrome",{"$nulls":5},"chromosome 17 open reading frame 107","[CQ107_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf107;+++[E5RJ01_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf107 {ECO:0000313|Ensembl:ENSP00000429241};"]
[100130357,"'LOC100130357'",5,4,11,6.66666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","uncharacterized LOC100130357","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RABX5_HUMAN|diamond]RecName: Full=Rab5 GDP/GTP exchange factor; AltName: Full=RAP1; AltName: Full=Rabaptin-5-associated exchange factor for Rab5; AltName: Full=Rabex-5;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[100130361,"'CXorf49'",0,0,1,0.333333333333333,{"$nulls":7},"chromosome X open reading frame 49","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100130370,"'LOC100130370'",111,67,84,87.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC100130370","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100130451,"'LOC100130451'",3,2,2,2.33333333333333,{"$nulls":7},"uncharacterized LOC100130451","[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[100130519,"'TMEM221'",25,41,66,44,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 221","[TM221_HUMAN|Reviewed]RecName: Full=Transmembrane protein 221;"]
[100130705,"'ATP6V1FNB'",34,19,33,28.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"ATP6V1F neighbor","[VAFNB_HUMAN|Reviewed]RecName: Full=Protein ATP6V1FNB {ECO:0000305}; AltName: Full=ATP6V1F neighbor gene protein {ECO:0000305};"]
[100130771,"'EFCAB10'",1,2,9,4,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0010494///cytoplasmic stress granule+++GO:0005576///extracellular region+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0070939///Dsl1/NZR complex+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0005509///calcium ion binding","GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0006397///mRNA processing+++GO:0015031///protein transport+++GO:0006351///transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0051781///positive regulation of cell division+++GO:1902504///regulation of signal transduction involved in mitotic G2 DNA damage checkpoint+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007049///cell cycle+++GO:0006355///regulation of transcription, DNA-templated","EF-hand calcium binding domain 10","[EFC10_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 10;+++[A0A2R8Y6P2_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000495682};+++[A0A2R8YDC4_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000494437};+++[C9J654_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000418425};+++[J3KR48_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417484}; SubName: Full=HCG1779729, isoform CRA_a {ECO:0000313|EMBL:EAW83368.1};+++[J3KR52_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417841};"]
[100130890,"'TSTD3'",73,95,87,85,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016592///mediator complex+++GO:0005829///cytosol+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0070911///global genome nucleotide-excision repair+++GO:0016579///protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1901409///positive regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:0006281///DNA repair+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II","thiosulfate sulfurtransferase like domain containing 3","[TSTD3_HUMAN|Reviewed]RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3; AltName: Full=Rhodanese domain-containing protein 3;+++[A0A1B0GUB9_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000490043};"]
[100130933,"'SMIM6'",1,3,0,1.33333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0016020///membrane+++GO:0071953///elastic fiber+++GO:0062023///collagen-containing extracellular matrix+++GO:0016021///integral component of membrane","GO:0050840///extracellular matrix binding+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0005515///protein binding+++GO:0005201///extracellular matrix structural constituent","GO:0007519///skeletal muscle tissue development+++GO:0043149///stress fiber assembly+++GO:0008283///cell proliferation+++GO:0003180///aortic valve morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0008015///blood circulation+++GO:0009887///animal organ morphogenesis+++GO:0030833///regulation of actin filament polymerization+++GO:0007585///respiratory gaseous exchange+++GO:0030198///extracellular matrix organization","small integral membrane protein 6","[SMIM6_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 6;+++[A7L3I8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:ABS29265.1};+++[D3DXF3_HUMAN|Unreviewed]SubName: Full=Elastin (Supravalvular aortic stenosis, Williams-Beuren syndrome), isoform CRA_b {ECO:0000313|EMBL:EAW69630.1};+++[E7EN51_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000403961}; Flags: Fragment;+++[E7ENW7_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000411092}; Flags: Fragment;+++[E7EP82_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000389206}; Flags: Fragment;+++[E7EQH8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000394549}; Flags: Fragment;+++[E7ETP7_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000406949}; Flags: Fragment;+++[E7EWS8_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000399499}; Flags: Fragment;+++[E9PGX4_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000404138};+++[H7C3K0_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|Ensembl:ENSP00000412262}; Flags: Fragment;+++[Q9UME9_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:AAC99789.1}; Flags: Fragment;+++[Q9UMK5_HUMAN|Unreviewed]SubName: Full=Elastin {ECO:0000313|EMBL:AAA52379.1}; Flags: Fragment;"]
[100130958,"'SYCE1L'",21,21,26,22.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04138///Autophagy - yeast",{"$nulls":3},"GO:0000795///synaptonemal complex+++GO:0045111///intermediate filament cytoskeleton",null,"GO:0051321///meiotic cell cycle+++GO:0070193///synaptonemal complex organization+++GO:0007130///synaptonemal complex assembly","synaptonemal complex central element protein 1 like","[SYC1L_HUMAN|Reviewed]RecName: Full=Synaptonemal complex central element protein 1-like; AltName: Full=Meiosis-related protein;+++[H3BME6_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex central element protein 1-like {ECO:0000313|Ensembl:ENSP00000454349}; Flags: Fragment;"]
[100130967,"'C6orf99'",11,21,19,17,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"chromosome 6 open reading frame 99","[CF099_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C6orf99;"]
[100131017,"'ZNF316'",711,663,590,654.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 316","[ZN316_HUMAN|Reviewed]RecName: Full=Zinc finger protein 316;+++[A0A087WZ61_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 316 {ECO:0000313|Ensembl:ENSP00000482395}; Flags: Fragment;"]
[100131187,"'TSTD1'",130,133,135,132.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005615///extracellular space+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005739///mitochondrion","GO:0008097///5S rRNA binding+++GO:0004792///thiosulfate sulfurtransferase activity+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0050337///thiosulfate-thiol sulfurtransferase activity","GO:0051029///rRNA transport+++GO:0030855///epithelial cell differentiation+++GO:0070221///sulfide oxidation, using sulfide:quinone oxidoreductase+++GO:0035928///rRNA import into mitochondrion+++GO:0000098///sulfur amino acid catabolic process+++GO:0009440///cyanate catabolic process","thiosulfate sulfurtransferase like domain containing 1","[TSTD1_HUMAN|Reviewed]RecName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000303|PubMed:24981631}; Short=TST {ECO:0000303|PubMed:24981631}; EC=2.8.1.- {ECO:0000269|PubMed:24981631};+++[B1AH48_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase {ECO:0000313|Ensembl:ENSP00000400764}; Flags: Fragment;+++[R4GNF9_HUMAN|Unreviewed]SubName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000313|Ensembl:ENSP00000473633};"]
[100131211,"'NEMP2'",13,16,16,15,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005635///nuclear envelope","GO:0003964///RNA-directed DNA polymerase activity",null,"nuclear envelope integral membrane protein 2","[NEMP2_HUMAN|Reviewed]RecName: Full=Nuclear envelope integral membrane protein 2; Flags: Precursor;+++[C9J4F2_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000410306}; Flags: Fragment;+++[F8VWJ7_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000340087};+++[H7C232_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000403867}; Flags: Fragment;"]
[100131244,"'ANKRD63'",4,6,13,7.66666666666667,{"$nulls":7},"ankyrin repeat domain 63","[ANR63_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 63 {ECO:0000312|HGNC:HGNC:40027};"]
[100131378,"'C11orf91'",1,3,3,2.33333333333333,{"$nulls":7},"chromosome 11 open reading frame 91","[CK091_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf91;+++[H0YDE1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf91 {ECO:0000313|Ensembl:ENSP00000433460}; Flags: Fragment;"]
[100131608,"'PRR23D1'",0,0.08,0.02,0.0333333333333333,{"$nulls":7},"proline rich 23 domain containing 1","[P23D1_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D1;+++[P23D2_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D2;"]
[100131755,"'ARMCX4'",105,69,70,81.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0016018///cyclosporin A binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0046790///virion binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0051082///unfolded protein binding","GO:0048469///cell maturation+++GO:0071226///cellular response to molecule of fungal origin+++GO:0035556///intracellular signal transduction+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0019061///uncoating of virus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0098761///cellular response to interleukin-7+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0034389///lipid droplet organization+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0002721///regulation of B cell cytokine production+++GO:0019076///viral release from host cell+++GO:0006351///transcription, DNA-templated+++GO:0045579///positive regulation of B cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0002553///histamine secretion by mast cell+++GO:0097190///apoptotic signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0006310///DNA recombination+++GO:0075713///establishment of integrated proviral latency+++GO:0045087///innate immune response+++GO:0002344///B cell affinity maturation+++GO:0050853///B cell receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0030260///entry into host cell+++GO:0019722///calcium-mediated signaling+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0002250///adaptive immune response+++GO:0034614///cellular response to reactive oxygen species+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0030889///negative regulation of B cell proliferation+++GO:0050900///leukocyte migration+++GO:0019058///viral life cycle+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0007498///mesoderm development+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0019068///virion assembly+++GO:0042113///B cell activation+++GO:0045069///regulation of viral genome replication+++GO:0002902///regulation of B cell apoptotic process+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0001818///negative regulation of cytokine production+++GO:0006468///protein phosphorylation+++GO:0032197///transposition, RNA-mediated","armadillo repeat containing X-linked 4","[ARMX4_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 4;+++[A0A024RCH4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 4, isoform CRA_b {ECO:0000313|EMBL:EAX02871.1};+++[D6RBS8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000422573};+++[F8W8Y7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000404304};+++[L8EAW9_HUMAN|Unreviewed]SubName: Full=Alternative protein ARMCX4 {ECO:0000313|EMBL:CCQ43981.1};"]
[100131801,"'PET100'",148,174,269,197,"03040///Spliceosome","H01368///Cytochrome c oxidase (COX) deficiency","M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0051082///unfolded protein binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","PET100 homolog","[PT100_HUMAN|Reviewed]RecName: Full=Protein PET100 homolog, mitochondrial; Flags: Precursor;+++[A0A0A0MSK2_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000392303};+++[M0QZ55_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470314}; Flags: Fragment;+++[M0R022_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470935};"]
[100131827,"'ZNF717'",46,47,50,47.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 717","[ZN717_HUMAN|Reviewed]RecName: Full=Zinc finger protein 717; AltName: Full=Krueppel-like factor X17;+++[C9J5W8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000417902};+++[C9J8I7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000418187}; Flags: Fragment;+++[C9JVC3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000419377};+++[E5RKB3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000420241}; Flags: Fragment;"]
[100131897,"'INSYN2B'",62,52,55,56.3333333333333,"04062///Chemokine signaling pathway+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0035580///specific granule lumen+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0042608///T cell receptor binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0050766///positive regulation of phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0001766///membrane raft polarization+++GO:0045059///positive thymic T cell selection+++GO:0044351///macropinocytosis+++GO:0045060///negative thymic T cell selection+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0006935///chemotaxis+++GO:0050690///regulation of defense response to virus by virus+++GO:0001771///immunological synapse formation+++GO:0007264///small GTPase mediated signal transduction+++GO:0001768///establishment of T cell polarity+++GO:0046633///alpha-beta T cell proliferation","inhibitory synaptic factor family member 2B","[INY2B_HUMAN|Reviewed]RecName: Full=Protein INSYN2B {ECO:0000305}; AltName: Full=Inhibitory synaptic factor family member 2B {ECO:0000312|HGNC:HGNC:37271};"]
[100131980,"'ZNF705G'",0,0,1,0.333333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 705G","[Z705G_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 705G;+++[A0A0G2JMF9_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 705G {ECO:0000313|Ensembl:ENSP00000479140};"]
[100132074,"'FOXO6'",201,275,269,248.333333333333,"04068///FoxO signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0042593///glucose homeostasis+++GO:0008286///insulin receptor signaling pathway+++GO:0007613///memory+++GO:0060999///positive regulation of dendritic spine development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","forkhead box O6","[FOXO6_HUMAN|Reviewed]RecName: Full=Forkhead box protein O6;+++[A0A1X9RU27_HUMAN|Unreviewed]SubName: Full=Forkhead box protein O6 {ECO:0000313|EMBL:ARQ84049.1};"]
[100132247,"'NPIPB5'",3200.13,2558.17,2480.3,2746.2,"00650///Butanoate metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++01100///Metabolic pathways",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane",null,null,"nuclear pore complex interacting protein family member B5","[NPIB5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B5;+++[B4E0Y1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61599 {ECO:0000313|EMBL:BAG64593.1};+++[E5RHP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000456511}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000429523}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000428548}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449726};+++[E7EUG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000392155};+++[E9PKP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000431553}; Flags: Fragment;+++[F5GWQ4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000457242}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000442776}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441759}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449771};+++[F5GXZ6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000440137}; Flags: Fragment;+++[F5GYP3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441303}; Flags: Fragment;+++[F5GZP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000444299}; Flags: Fragment;+++[F5H6Y6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442935}; Flags: Fragment;+++[F6SDX0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000445388}; Flags: Fragment;+++[H0YIL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000449628}; Flags: Fragment;+++[U3KRG3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442912}; Flags: Fragment;"]
[100132406,"'NBPF10'",1013.75,853.84,458.29,775.293333333333,"01522///Endocrine resistance+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++04140///Autophagy - animal+++05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation+++04137///Mitophagy - animal+++05224///Breast cancer","H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0003723///RNA binding","GO:0007275///multicellular organism development+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway","NBPF member 10","[NBPFA_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 10;+++[A0A075B762_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000463957};+++[A0A087WVC7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000479344};+++[A0A087WVG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000479415};+++[A0A087WYQ9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482016};+++[A0A087WZE1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482587};+++[A0A087X0Y3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000483736};+++[A2BH96_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 10 {ECO:0000313|EMBL:CAM23768.1};+++[I0CMK7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFH78588.1}; Flags: Fragment;+++[I1VE12_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41822.1}; Flags: Fragment;+++[I1VE13_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41823.1}; Flags: Fragment;+++[I1VE14_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41824.1}; Flags: Fragment;+++[L8E7E2_HUMAN|Unreviewed]SubName: Full=Alternative protein NBPF9 {ECO:0000313|EMBL:CCQ43049.1};+++[Q5TB04_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 9 {ECO:0000313|EMBL:CAI22821.1}; Flags: Fragment;"]
[100132874,"'LOC100132874'",1,2,1,1.33333333333333,{"$nulls":7},"uncharacterized LOC100132874","[RRBP1_MOUSE|diamond]RecName: Full=Ribosome-binding protein 1; AltName: Full=Ribosome receptor protein; Short=RRp; Short=mRRp;+++[SRFB1_XENTR|diamond]RecName: Full=Serum response factor-binding protein 1; AltName: Full=SRF-dependent transcription regulation-associated protein;"]
[100132911,"'DPH3P1'",0,2.71,0,0.903333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046872///metal ion binding","GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0002098///tRNA wobble uridine modification","diphthamide biosynthesis 3 pseudogene 1","[DPH3B_HUMAN|Reviewed]RecName: Full=Putative DPH3 homolog B; AltName: Full=CSL-type zinc finger-containing protein 1;"]
[100132994,"'CXorf49B'",0,0,1,0.333333333333333,{"$nulls":7},"chromosome X open reading frame 49B","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100133093,"'FAM25G'",0,2,0,0.666666666666667,{"$nulls":7},"family with sequence similarity 25 member G","[FM25A_HUMAN|Reviewed]RecName: Full=Protein FAM25A {ECO:0000305};+++[FM25C_HUMAN|Reviewed]RecName: Full=Protein FAM25C {ECO:0000305};+++[FM25G_HUMAN|Reviewed]RecName: Full=Protein FAM25G {ECO:0000305};+++[B7ZW47_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 25, member C {ECO:0000313|EMBL:AAI71871.1};"]
[100133204,"'C9orf147'",3,0,7,3.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0016020///membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0051213///dioxygenase activity","GO:0010468///regulation of gene expression","chromosome 9 open reading frame 147","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[HSDL2_BOVIN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_HUMAN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-; AltName: Full=Short chain dehydrogenase/reductase family 13C member 1;+++[HSDL2_PONAB|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENLA|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENTR|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100133220,"'GOLGA6L3'",2.02,3.59,1.56,2.39,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"golgin A6 family-like 3","[GG6L3_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 3;"]
[100133251,"'PRR23D2'",0,3.92,0.98,1.63333333333333,{"$nulls":7},"proline rich 23 domain containing 2","[P23D1_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D1;+++[P23D2_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D2;"]
[100133301,"'100133301'",3,10,3,5.33333333333333,{"$nulls":8},"[F231A_HUMAN|diamond]RecName: Full=Putative protein FAM231AP {ECO:0000305};+++[F231B_HUMAN|diamond]RecName: Full=Putative protein FAM231BP;+++[F231C_HUMAN|diamond]RecName: Full=Protein FAM231C;+++[F231D_HUMAN|diamond]RecName: Full=Protein FAM231D;+++[F231L_HUMAN|diamond]RecName: Full=FAM231A/C-like protein LOC102723383;"]
[100133941,"'CD24'",2891,3594,3283,3256,"04640///Hematopoietic cell lineage",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0045121///membrane raft+++GO:0009986///cell surface+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030296///protein tyrosine kinase activator activity","GO:0032597///B cell receptor transport into membrane raft+++GO:0032913///negative regulation of transforming growth factor beta3 production+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0030856///regulation of epithelial cell differentiation+++GO:0045730///respiratory burst+++GO:0043406///positive regulation of MAP kinase activity+++GO:0016055///Wnt signaling pathway+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:2000768///positive regulation of nephron tubule epithelial cell differentiation+++GO:0001775///cell activation+++GO:0042632///cholesterol homeostasis+++GO:0002237///response to molecule of bacterial origin+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072139///glomerular parietal epithelial cell differentiation+++GO:0001666///response to hypoxia+++GO:0042325///regulation of phosphorylation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0032600///chemokine receptor transport out of membrane raft+++GO:0043408///regulation of MAPK cascade+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0031295///T cell costimulation+++GO:0043627///response to estrogen+++GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0098609///cell-cell adhesion","CD24 molecule","[CD24_HUMAN|Reviewed]RecName: Full=Signal transducer CD24; AltName: Full=Small cell lung carcinoma cluster 4 antigen; AltName: CD_antigen=CD24; Flags: Precursor;+++[A0A087WU21_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478302};+++[A0A087WU87_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478460}; Flags: Fragment;+++[A0A087WW33_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000479895}; Flags: Fragment;"]
[100134444,"'KCNJ18'",0,3.8,0,1.26666666666667,"04725///Cholinergic synapse+++04921///Oxytocin signaling pathway","H00747///Thyrotoxic hypokalemic periodic paralysis (TPP)",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005244///voltage-gated ion channel activity+++GO:0005242///inward rectifier potassium channel activity","GO:0006811///ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0006813///potassium ion transport+++GO:1990573///potassium ion import across plasma membrane","potassium voltage-gated channel subfamily J member 18","[KCJ18_HUMAN|Reviewed]RecName: Full=Inward rectifier potassium channel 18; AltName: Full=Inward rectifier K(+) channel Kir2.6; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 18;"]
[100134934,"'TEN1'",160,171,179,170,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0005634///nucleus+++GO:0000781///chromosome, telomeric region+++GO:1990879///CST complex+++GO:0005694///chromosome","GO:0042162///telomeric DNA binding+++GO:0005515///protein binding+++GO:0010521///telomerase inhibitor activity+++GO:0003697///single-stranded DNA binding+++GO:0003677///DNA binding","GO:0016233///telomere capping+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0051974///negative regulation of telomerase activity","TEN1, CST complex subunit","[TEN1L_HUMAN|Reviewed]RecName: Full=CST complex subunit TEN1; AltName: Full=Protein telomeric pathways with STN1 homolog; AltName: Full=Telomere length regulation protein TEN1 homolog;+++[D3U720_HUMAN|Unreviewed]SubName: Full=Telomeric pathways in association with Stn1 number 1 {ECO:0000313|EMBL:ACY71128.1};+++[K7EIL0_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000464792}; Flags: Fragment;+++[K7EJS2_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465299}; Flags: Fragment;+++[K7EL09_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465866};"]
[100134938,"'UPK3BL1'",316.22,297.63,289.52,301.123333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"uroplakin 3B like 1","[UPK3L_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 1 {ECO:0000312|HGNC:HGNC:37278}; Flags: Precursor;+++[UPKL2_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 2 {ECO:0000305}; Flags: Precursor;"]
[100137047,"'JMJD7'",82.37,94.45,84.02,86.9466666666667,{"$nulls":5},"GO:0005515///protein binding",null,"jumonji domain containing 7","[JMJD7_HUMAN|Reviewed]RecName: Full=JmjC domain-containing protein 7; AltName: Full=Jumonji domain-containing protein 7;+++[B5MC20_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000384174};+++[C9K0I3_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000399600}; Flags: Fragment;"]
[100137049,"'PLA2G4B'",0,0,32.43,10.81,"04726///Serotonergic synapse+++04611///Platelet activation+++04913///Ovarian steroidogenesis+++04730///Long-term depression+++04921///Oxytocin signaling pathway+++04072///Phospholipase D signaling pathway+++00564///Glycerophospholipid metabolism+++04750///Inflammatory mediator regulation of TRP channels+++00591///Linoleic acid metabolism+++00590///Arachidonic acid metabolism+++04014///Ras signaling pathway+++04217///Necroptosis+++01110///Biosynthesis of secondary metabolites+++00592///alpha-Linolenic acid metabolism+++01100///Metabolic pathways+++04724///Glutamatergic synapse+++00565///Ether lipid metabolism+++04010///MAPK signaling pathway+++04370///VEGF signaling pathway+++04270///Vascular smooth muscle contraction+++04912///GnRH signaling pathway+++05231///Choline metabolism in cancer+++04664///Fc epsilon RI signaling pathway",null,null,"R01315///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid+++R01317///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate+++R07379///plasmenylethanolamine 2-acylhydrolase   O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate+++R07064///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate+++R07387///plasmanylcholine 2-acylhydrolase   1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate+++R02053///phosphatidylethanolamine 2-acylhydrolase   Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid+++R07859///Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid","GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031966///mitochondrial membrane+++GO:0031901///early endosome membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm","GO:0008970///phospholipase A1 activity+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0004623///phospholipase A2 activity+++GO:0004622///lysophospholipase activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding+++GO:0004620///phospholipase activity","GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0007567///parturition+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0046475///glycerophospholipid catabolic process+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0019369///arachidonic acid metabolic process+++GO:0006644///phospholipid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0009395///phospholipid catabolic process+++GO:0019722///calcium-mediated signaling+++GO:0006629///lipid metabolic process+++GO:0006954///inflammatory response+++GO:0016042///lipid catabolic process+++GO:0006654///phosphatidic acid biosynthetic process","phospholipase A2 group IVB","[PA24B_HUMAN|Reviewed]RecName: Full=Cytosolic phospholipase A2 beta; Short=cPLA2-beta; EC=3.1.1.4; AltName: Full=Phospholipase A2 group IVB;+++[H3BSX5_HUMAN|Unreviewed]SubName: Full=Cytosolic phospholipase A2 beta {ECO:0000313|Ensembl:ENSP00000456919}; Flags: Fragment;"]
[10014,"'HDAC5'",1379,1317,1346,1347.33333333333,"04371///Apelin signaling pathway+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05034///Alcoholism+++05203///Viral carcinogenesis","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0005829///cytosol+++GO:0000118///histone deacetylase complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0008134///transcription factor binding+++GO:0003682///chromatin binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0070491///repressing transcription factor binding+++GO:0005515///protein binding+++GO:0005080///protein kinase C binding+++GO:0033558///protein deacetylase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0030183///B cell differentiation+++GO:0010830///regulation of myotube differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006954///inflammatory response+++GO:0042113///B cell activation+++GO:0014823///response to activity+++GO:0010832///negative regulation of myotube differentiation+++GO:0042493///response to drug+++GO:0043393///regulation of protein binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042220///response to cocaine+++GO:0040029///regulation of gene expression, epigenetic+++GO:0030182///neuron differentiation+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0006338///chromatin remodeling+++GO:0070932///histone H3 deacetylation+++GO:0006476///protein deacetylation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006325///chromatin organization+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0006342///chromatin silencing+++GO:0016575///histone deacetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032869///cellular response to insulin stimulus","histone deacetylase 5","[HDAC5_HUMAN|Reviewed]RecName: Full=Histone deacetylase 5; Short=HD5; EC=3.5.1.98; AltName: Full=Antigen NY-CO-9;+++[K7EJL4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465227}; Flags: Fragment;+++[K7EJL6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465229}; Flags: Fragment;+++[K7EJZ7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465393}; Flags: Fragment;+++[K7ES01_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000468485}; Flags: Fragment;"]
[100141515,"'C17orf99'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005125///cytokine activity","GO:0010469///regulation of signaling receptor activity+++GO:0002376///immune system process+++GO:2000558///positive regulation of immunoglobulin production in mucosal tissue+++GO:0002250///adaptive immune response+++GO:0002313///mature B cell differentiation involved in immune response","chromosome 17 open reading frame 99","[IL40_HUMAN|Reviewed]RecName: Full=Protein IL-40 {ECO:0000305}; AltName: Full=Interleukin-40 {ECO:0000303|PubMed:28978694}; Short=IL-40 {ECO:0000303|PubMed:28978694}; Flags: Precursor;+++[A0A0D9SGD8_HUMAN|Unreviewed]SubName: Full=Protein IL-40 {ECO:0000313|Ensembl:ENSP00000487393}; Flags: Fragment;+++[K7ELL6_HUMAN|Unreviewed]SubName: Full=Protein IL-40 {ECO:0000313|Ensembl:ENSP00000466133}; Flags: Fragment;"]
[100142659,"'CTAGE8'",34.18,24.94,51.23,36.7833333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0042954///lipoprotein transporter activity","GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0042953///lipoprotein transport","CTAGE family member 8","[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[CTGE8_HUMAN|Reviewed]RecName: Full=cTAGE family member 8; Short=Protein cTAGE-8;"]
[100144748,"'KLLN'",50,41,39,43.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003677///DNA binding","GO:0006915///apoptotic process+++GO:0007050///cell cycle arrest+++GO:0007049///cell cycle","killin, p53 regulated DNA replication inhibitor","[KILIN_HUMAN|Reviewed]RecName: Full=Killin;"]
[10015,"'PDCD6IP'",2209,2249,2127,2195,"04144///Endocytosis",{"$nulls":3},"GO:0001772///immunological synapse+++GO:0005923///bicellular tight junction+++GO:0042470///melanosome+++GO:0070971///endoplasmic reticulum exit site+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:1903561///extracellular vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0042641///actomyosin+++GO:0005815///microtubule organizing center+++GO:0005925///focal adhesion+++GO:0090543///Flemming body","GO:0048306///calcium-dependent protein binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0031871///proteinase activated receptor binding","GO:1903543///positive regulation of exosomal secretion+++GO:0070830///bicellular tight junction assembly+++GO:0007080///mitotic metaphase plate congression+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:0019058///viral life cycle+++GO:0016032///viral process+++GO:0046755///viral budding+++GO:1903551///regulation of extracellular exosome assembly+++GO:0015031///protein transport+++GO:0006997///nucleus organization+++GO:0000281///mitotic cytokinesis+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0007049///cell cycle+++GO:1901673///regulation of mitotic spindle assembly+++GO:0000915///actomyosin contractile ring assembly+++GO:0039702///viral budding via host ESCRT complex+++GO:0051260///protein homooligomerization+++GO:0010824///regulation of centrosome duplication+++GO:0036258///multivesicular body assembly+++GO:1903553///positive regulation of extracellular exosome assembly+++GO:0006915///apoptotic process+++GO:0090559///regulation of membrane permeability+++GO:0061952///midbody abscission+++GO:0051301///cell division","programmed cell death 6 interacting protein","[PDC6I_HUMAN|Reviewed]RecName: Full=Programmed cell death 6-interacting protein; Short=PDCD6-interacting protein; AltName: Full=ALG-2-interacting protein 1; AltName: Full=ALG-2-interacting protein X; AltName: Full=Hp95;+++[C9IZF9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000406693}; Flags: Fragment;+++[F8WBR8_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000398895};+++[F8WDK9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000415150};+++[F8WEQ7_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000393777};+++[Q4W4Y1_HUMAN|Unreviewed]SubName: Full=Dopamine receptor interacting protein 4 {ECO:0000313|EMBL:AAQ14260.1};"]
[10016,"'PDCD6'",456,465,561,494,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030127///COPII vesicle coat+++GO:0070062///extracellular exosome+++GO:0005768///endosome+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0015629///actin cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0060090///molecular adaptor activity+++GO:0005509///calcium ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0000287///magnesium ion binding+++GO:0004378///GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0102704///GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity","GO:1902527///positive regulation of protein monoubiquitination+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0014029///neural crest formation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097502///mannosylation+++GO:0006486///protein glycosylation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0001525///angiogenesis+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0034605///cellular response to heat+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006886///intracellular protein transport+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006915///apoptotic process+++GO:0051592///response to calcium ion+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0014032///neural crest cell development+++GO:0045766///positive regulation of angiogenesis+++GO:0010595///positive regulation of endothelial cell migration","programmed cell death 6","[PDCD6_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 6; AltName: Full=Apoptosis-linked gene 2 protein homolog {ECO:0000250|UniProtKB:P12815}; Short=ALG-2 {ECO:0000250|UniProtKB:P12815};+++[A0A024QZ42_HUMAN|Unreviewed]SubName: Full=HCG1985580, isoform CRA_c {ECO:0000313|EMBL:EAW50990.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000485024};+++[A0A087WZ38_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000482332};+++[D6RA21_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000424201};+++[E7EPW6_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000426003};+++[H0Y9X3_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000425370}; Flags: Fragment;+++[Q53FC3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6 variant {ECO:0000313|EMBL:BAD97086.1}; Flags: Fragment;+++[Q86W51_HUMAN|Unreviewed]SubName: Full=PDCD6 protein {ECO:0000313|EMBL:AAH50597.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000422691};"]
[10017,"'BCL2L10'",5,0,2,2.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0089720///caspase binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0007283///spermatogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007292///female gamete generation","BCL2 like 10","[B2L10_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 10; Short=Bcl2-L-10; AltName: Full=Anti-apoptotic protein NrH; AltName: Full=Apoptosis regulator Bcl-B;+++[H0YMD5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 10 {ECO:0000313|Ensembl:ENSP00000453562};"]
[100170229,"'SRRM5'",7,6,6,6.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","serine/arginine repetitive matrix 5","[SRRM5_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 5;+++[Q4G0Z0_HUMAN|Unreviewed]SubName: Full=LOC100170229 protein {ECO:0000313|EMBL:AAH34980.1}; Flags: Fragment;"]
[100170841,"'EPOP'",54,74,75,67.6666666666667,{"$nulls":4},"GO:0070449///elongin complex+++GO:0035098///ESC/E(Z) complex+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0003682///chromatin binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0048863///stem cell differentiation+++GO:0048663///neuron fate commitment","elongin BC and polycomb repressive complex 2 associated protein","[EPOP_HUMAN|Reviewed]RecName: Full=Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8}; AltName: Full=Proline-rich protein 28 {ECO:0000312|HGNC:HGNC:34493};"]
[10018,"'BCL2L11'",114,121,90,108.333333333333,"04210///Apoptosis+++05206///MicroRNAs in cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++04215///Apoptosis - multiple species+++01521///EGFR tyrosine kinase inhibitor resistance+++05210///Colorectal cancer+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0005829///cytosol+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex+++GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097140///BIM-BCL-xl complex+++GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0097141///BIM-BCL-2 complex","GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0019901///protein kinase binding","GO:0008584///male gonad development+++GO:0048536///spleen development+++GO:0035148///tube formation+++GO:0001822///kidney development+++GO:0048538///thymus development+++GO:0009791///post-embryonic development+++GO:0001783///B cell apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0007420///brain development+++GO:0045787///positive regulation of cell cycle+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0048066///developmental pigmentation+++GO:0002262///myeloid cell homeostasis+++GO:0001701///in utero embryonic development+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0032464///positive regulation of protein homooligomerization+++GO:0010942///positive regulation of cell death+++GO:0070242///thymocyte apoptotic process+++GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0007160///cell-matrix adhesion+++GO:0002260///lymphocyte homeostasis+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0001782///B cell homeostasis+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:0046620///regulation of organ growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0030879///mammary gland development+++GO:0043583///ear development+++GO:0006915///apoptotic process+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0043029///T cell homeostasis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0001776///leukocyte homeostasis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043065///positive regulation of apoptotic process+++GO:0034263///positive regulation of autophagy in response to ER overload+++GO:0048070///regulation of developmental pigmentation+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0007283///spermatogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0060154///cellular process regulating host cell cycle in response to virus+++GO:0060139///positive regulation of apoptotic process by virus","BCL2 like 11","[B2L11_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 11; Short=Bcl2-L-11; AltName: Full=Bcl2-interacting mediator of cell death;+++[A0A0A0MRE7_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000350398};+++[A0A0C4DH20_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000354879};+++[C9J417_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000411870}; Flags: Fragment;+++[E9PAM9_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000376941}; Flags: Fragment;+++[H7BZE5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000389225}; Flags: Fragment;"]
[100188893,"'TOMM6'",586,578,687,617,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005742///mitochondrial outer membrane translocase complex",null,"GO:0015031///protein transport","translocase of outer mitochondrial membrane 6","[TOM6_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM6 homolog; AltName: Full=Overexpressed breast tumor protein; AltName: Full=Translocase of outer membrane 6 kDa subunit homolog;"]
[10019,"'SH2B3'",227,232,192,217,"04722///Neurotrophin signaling pathway","H00408///Type I diabetes mellitus",null,null,"GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0035591///signaling adaptor activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding","GO:0007596///blood coagulation+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0009967///positive regulation of signal transduction+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0035162///embryonic hemopoiesis","SH2B adaptor protein 3","[SH2B3_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 3; AltName: Full=Lymphocyte adapter protein; AltName: Full=Lymphocyte-specific adapter protein Lnk; AltName: Full=Signal transduction protein Lnk;+++[B7Z7K6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54917, highly similar to Lymphocyte-specific adapter protein Lnk {ECO:0000313|EMBL:BAH13642.1};+++[F5GYM4_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000440597};+++[Q59H48_HUMAN|Unreviewed]SubName: Full=Lymphocyte adaptor protein variant {ECO:0000313|EMBL:BAD92148.1}; Flags: Fragment;+++[Q96BA5_HUMAN|Unreviewed]SubName: Full=SH2B3 protein {ECO:0000313|EMBL:AAH15786.1};+++[R4GN84_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000473529}; Flags: Fragment;"]
[100190949,"'C5orf52'",0,1,0,0.333333333333333,{"$nulls":7},"chromosome 5 open reading frame 52","[CE052_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf52;"]
[100191040,"'C2CD4D'",13,9,17,13,{"$nulls":4},"GO:0098793///presynapse+++GO:0005886///plasma membrane","GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding",null,"C2 calcium dependent domain containing 4D","[C2D4D_HUMAN|Reviewed]RecName: Full=C2 calcium-dependent domain-containing protein 4D;"]
[1002,"'CDH4'",108,128,102,112.666666666667,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0016342///catenin complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007411///axon guidance+++GO:0045773///positive regulation of axon extension+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization","cadherin 4","[CADH4_HUMAN|Reviewed]RecName: Full=Cadherin-4; AltName: Full=Retinal cadherin; Short=R-CAD; Short=R-cadherin; Flags: Precursor;+++[A0A087WX99_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000480844};+++[A0A0G2JRA4_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000486568}; Flags: Fragment;"]
[10020,"'GNE'",306.16,235,253.91,265.023333333333,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H00596///Nonaka distal myopathy (NM)+++H00594///Distal myopathy+++H00147///Sialuria",null,"R02705///ATP:N-acyl-D-mannosamine 6-phosphotransferase   ATP + N-Acetyl-D-mannosamine <=> ADP + N-Acetyl-D-mannosamine 6-phosphate+++R00414///UDP-N-acetyl-D-glucosamine 2-epimerase   UDP-N-acetyl-alpha-D-glucosamine + H2O <=> N-Acetyl-D-mannosamine + UDP","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008761///UDP-N-acetylglucosamine 2-epimerase activity+++GO:0009384///N-acylmannosamine kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity+++GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0008152///metabolic process+++GO:0006054///N-acetylneuraminate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006045///N-acetylglucosamine biosynthetic process+++GO:0007155///cell adhesion+++GO:0016310///phosphorylation","glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase","[GLCNE_HUMAN|Reviewed]RecName: Full=Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; AltName: Full=UDP-GlcNAc-2-epimerase/ManAc kinase; Includes: RecName: Full=UDP-N-acetylglucosamine 2-epimerase (hydrolyzing); EC=3.2.1.183; AltName: Full=UDP-GlcNAc-2-epimerase; AltName: Full=Uridine diphosphate-N-acetylglucosamine-2-epimerase; Includes: RecName: Full=N-acetylmannosamine kinase; EC=2.7.1.60; AltName: Full=ManAc kinase;+++[Q6QNY5_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59259.1};+++[Q6QNY6_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59258.1};+++[Q6QNY7_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59257.1};"]
[10021,"'HCN4'",16,47,33,32,"04024///cAMP signaling pathway+++04742///Taste transduction","H00729///Sick sinus syndrome (SSS)+++H00728///Brugada syndrome (BRS)",null,null,"GO:0098855///HCN channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0005267///potassium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0042802///identical protein binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0030552///cAMP binding+++GO:0005249///voltage-gated potassium channel activity+++GO:0086041///voltage-gated potassium channel activity involved in SA node cell action potential depolarization+++GO:0000166///nucleotide binding+++GO:0005272///sodium channel activity","GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0071321///cellular response to cGMP+++GO:0006813///potassium ion transport+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0008015///blood circulation+++GO:0071805///potassium ion transmembrane transport+++GO:0086015///SA node cell action potential+++GO:0098719///sodium ion import across plasma membrane+++GO:0003254///regulation of membrane depolarization+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0006936///muscle contraction+++GO:0034765///regulation of ion transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0002027///regulation of heart rate+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential","hyperpolarization activated cyclic nucleotide gated potassium channel 4","[HCN4_HUMAN|Reviewed]RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4;"]
[10023,"'FRAT1'",9,35,18,20.6666666666667,"05200///Pathways in cancer+++05225///Hepatocellular carcinoma+++04310///Wnt signaling pathway+++05224///Breast cancer+++05226///Gastric cancer",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding","GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0060070///canonical Wnt signaling pathway+++GO:1904886///beta-catenin destruction complex disassembly","FRAT1, WNT signaling pathway regulator","[FRAT1_HUMAN|Reviewed]RecName: Full=Proto-oncogene FRAT1; AltName: Full=Frequently rearranged in advanced T-cell lymphomas 1; Short=FRAT-1;+++[D3DR49_HUMAN|Unreviewed]SubName: Full=Frequently rearranged in advanced T-cell lymphomas, isoform CRA_a {ECO:0000313|EMBL:EAW49951.1};"]
[10024,"'TROAP'",5,1,0,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0007155///cell adhesion","trophinin associated protein","[TROAP_HUMAN|Reviewed]RecName: Full=Tastin; AltName: Full=Trophinin-assisting protein; AltName: Full=Trophinin-associated protein;+++[B7Z5Q9_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000450306}; SubName: Full=cDNA FLJ50628, highly similar to Trophinin-associated protein {ECO:0000313|EMBL:BAH12995.1};+++[F8VR46_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446564};+++[F8VVS4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449588}; Flags: Fragment;+++[F8VVT5_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449245};+++[F8VVX4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449866};+++[F8VXF3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449984};+++[F8VXV6_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449032};+++[F8W052_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447244}; Flags: Fragment;+++[F8W130_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447509};+++[F8W1E3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446646}; Flags: Fragment;+++[F8W1U0_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447421};"]
[10025,"'MED16'",1209,1169,1205,1194.33333333333,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005634///nucleus","GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0003824///catalytic activity+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042809///vitamin D receptor binding","GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030518///intracellular steroid hormone receptor signaling pathway","mediator complex subunit 16","[MED16_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16; AltName: Full=Mediator complex subunit 16; AltName: Full=Thyroid hormone receptor-associated protein 5; AltName: Full=Thyroid hormone receptor-associated protein complex 95 kDa component; Short=Trap95; AltName: Full=Vitamin D3 receptor-interacting protein complex 92 kDa component; Short=DRIP92;+++[A0A087WU12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YW49_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXA0_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000488370}; Flags: Fragment;+++[A0A0J9YXK9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXL6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YY02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YYC6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ7_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i4 {ECO:0000313|EMBL:ACB88883.1}; Flags: Fragment;+++[B9TWZ8_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX00_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX01_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX03_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i10 {ECO:0000313|EMBL:ACB88889.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000480766}; Flags: Fragment;+++[B9TX04_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX05_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX06_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX07_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i14 {ECO:0000313|EMBL:ACB88893.1}; Flags: Fragment;+++[B9TX08_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i15 {ECO:0000313|EMBL:ACB88894.1}; Flags: Fragment;+++[B9TX09_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX10_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i17 {ECO:0000313|EMBL:ACB88896.1}; Flags: Fragment;+++[B9TX11_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX13_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i20 {ECO:0000313|EMBL:ACB88899.1}; Flags: Fragment;+++[B9TX14_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i21 {ECO:0000313|EMBL:ACB88900.1};+++[B9TX15_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i22 {ECO:0000313|EMBL:ACB88901.1}; Flags: Fragment;+++[B9TX16_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i23 {ECO:0000313|EMBL:ACB88902.1};+++[B9TX17_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i24 {ECO:0000313|EMBL:ACB88903.1};+++[B9TX18_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i25 {ECO:0000313|EMBL:ACB88904.1};+++[B9TX19_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i26 {ECO:0000313|EMBL:ACB88905.1};+++[B9TX20_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i27 {ECO:0000313|EMBL:ACB88906.1};+++[B9TX21_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i28 {ECO:0000313|EMBL:ACB88907.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000483533};+++[B9TX22_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i29 {ECO:0000313|EMBL:ACB88908.1};+++[B9TX23_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i30 {ECO:0000313|EMBL:ACB88909.1};+++[B9TX24_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i31 {ECO:0000313|EMBL:ACB88910.1};+++[B9TX25_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i32 {ECO:0000313|EMBL:ACB88911.1};+++[B9TX26_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX27_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i34 {ECO:0000313|EMBL:ACB88913.1};+++[B9TX28_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i35 {ECO:0000313|EMBL:ACB88914.1};+++[K7EKS6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[K7EKX2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465823};+++[K7EKX6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465827}; Flags: Fragment;+++[U3KQ43_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[U3KQB4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;"]
[10026,"'PIGK'",675,645,621,647,"01100///Metabolic pathways+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis",{"$nulls":3},"GO:0042765///GPI-anchor transamidase complex+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0003923///GPI-anchor transamidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0003756///protein disulfide isomerase activity+++GO:0016787///hydrolase activity+++GO:0034235///GPI anchor binding+++GO:0005515///protein binding","GO:0006508///proteolysis+++GO:0016255///attachment of GPI anchor to protein+++GO:0006506///GPI anchor biosynthetic process","phosphatidylinositol glycan anchor biosynthesis class K","[GPI8_HUMAN|Reviewed]RecName: Full=GPI-anchor transamidase; Short=GPI transamidase; EC=3.-.-.-; AltName: Full=GPI8 homolog; Short=hGPI8; AltName: Full=Phosphatidylinositol-glycan biosynthesis class K protein; Short=PIG-K; Flags: Precursor;+++[A6NEM5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000352041};+++[B1AK81_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000388854}; SubName: Full=Phosphatidylinositol glycan, class K, isoform CRA_c {ECO:0000313|EMBL:EAX06382.1};+++[S4R3M5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000474518}; Flags: Fragment;"]
[100271715,"'ARHGEF33'",0,6,4,3.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0035023///regulation of Rho protein signal transduction","Rho guanine nucleotide exchange factor 33","[ARG33_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 33;+++[H7C1C9_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 33 {ECO:0000313|Ensembl:ENSP00000399688};"]
[100271849,"'MEF2B'",41.14,40.56,67.36,49.6866666666667,"04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway","H01613///Follicular lymphoma",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0042826///histone deacetylase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007517///muscle organ development","myocyte enhancer factor 2B","[MEF2B_HUMAN|Reviewed]RecName: Full=Myocyte-specific enhancer factor 2B; AltName: Full=RSRFR2; AltName: Full=Serum response factor-like protein 2;+++[A0A024R7K5_HUMAN|Unreviewed]SubName: Full=MADS box transcription enhancer factor 2, polypeptide B (Myocyte enhancer factor 2B), isoform CRA_a {ECO:0000313|EMBL:EAW84793.1};+++[B3KQ23_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386480}; SubName: Full=cDNA FLJ32648 fis, clone SYNOV2001451, highly similar to MYOCYTE-SPECIFIC ENHANCER FACTOR 2B {ECO:0000313|EMBL:BAG51885.1};+++[B8ZZJ5_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386784};+++[C9J4J4_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386374};"]
[100271927,"'RASA4B'",167.67,138.3,128.63,144.866666666667,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0005543///phospholipid binding+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0071277///cellular response to calcium ion+++GO:0043087///regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction","RAS p21 protein activator 4B","[RAS4B_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4B;+++[F5GXT2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000440982};+++[F8W6L0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000303968};"]
[100272147,"'CMC4'",139.54,163.35,104.87,135.92,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0032991///protein-containing complex","GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0008283///cell proliferation","C-X9-C motif containing 4","[CMC4_HUMAN|Reviewed]RecName: Full=Cx9C motif-containing protein 4; AltName: Full=Mature T-cell proliferation 1 neighbor protein; AltName: Full=Mature T-cell proliferation-1 type A; Short=MTCP-1 type A; AltName: Full=Protein p8 MTCP-1; Short=p8MTCP1;+++[A0A0G2JKI4_HUMAN|Unreviewed]SubName: Full=Protein p13 MTCP-1 {ECO:0000313|Ensembl:ENSP00000427132}; Flags: Fragment;+++[Q9NRK3_HUMAN|Unreviewed]SubName: Full=p8 protein {ECO:0000313|EMBL:AAF76750.1};"]
[100287045,"'FAM90A26'",0,0,1,0.333333333333333,{"$nulls":7},"family with sequence similarity 90 member A26","[F90AP_HUMAN|Reviewed]RecName: Full=Putative protein FAM90A26 {ECO:0000305};"]
[100287171,"'WASHC1'",3744,3969,3853,3855.33333333333,"04212///Longevity regulating pathway - worm+++04144///Endocytosis",{"$nulls":3},"GO:0071203///WASH complex+++GO:0005814///centriole+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005829///cytosol+++GO:0071437///invadopodium+++GO:0055038///recycling endosome membrane+++GO:0000145///exocyst+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005856///cytoskeleton+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005776///autophagosome+++GO:0031410///cytoplasmic vesicle","GO:0043014///alpha-tubulin binding+++GO:0003779///actin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0015031///protein transport+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0010507///negative regulation of autophagy+++GO:0030335///positive regulation of cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0006887///exocytosis+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031396///regulation of protein ubiquitination+++GO:0022617///extracellular matrix disassembly+++GO:0042147///retrograde transport, endosome to Golgi+++GO:1990126///retrograde transport, endosome to plasma membrane","WASH complex subunit 1","[WASH1_HUMAN|Reviewed]RecName: Full=WASH complex subunit 1 {ECO:0000312|HGNC:HGNC:24361}; AltName: Full=CXYorf1-like protein on chromosome 9; AltName: Full=Protein FAM39E; AltName: Full=WAS protein family homolog 1;+++[A0A2R8YDD3_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 1 {ECO:0000313|Ensembl:ENSP00000494459}; Flags: Fragment;+++[A9QQ12_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71499.1}; Flags: Fragment;+++[A9QQ13_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71500.1}; Flags: Fragment;+++[A9QQ14_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71501.1}; Flags: Fragment;+++[A9QQ15_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71502.1}; Flags: Fragment;+++[A9QQ16_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71503.1}; Flags: Fragment;+++[A9QQ17_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71504.1}; Flags: Fragment;+++[A9QQ18_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71505.1}; Flags: Fragment;+++[A9QQ19_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71506.1}; Flags: Fragment;+++[A9QQ20_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71507.1}; Flags: Fragment;+++[A9QQ21_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71508.1}; Flags: Fragment;+++[A9QQ22_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71509.1}; Flags: Fragment;+++[A9QQ23_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71510.1}; Flags: Fragment;"]
[100287178,"'USP17L11'",0,0.12,0,0.04,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0004197///cysteine-type endopeptidase activity","GO:0042981///regulation of apoptotic process+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process","ubiquitin specific peptidase 17-like family member 11","[U17LB_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 11; EC=3.4.19.12;+++[A0A087WTA0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 11 {ECO:0000313|Ensembl:ENSP00000477697};"]
[100287205,"'USP17L12'",0,0.12,0,0.04,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008234///cysteine-type peptidase activity","GO:0006508///proteolysis+++GO:0016579///protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0042981///regulation of apoptotic process","ubiquitin specific peptidase 17-like family member 12","[UL17C_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 12; EC=3.4.19.12;"]
[100287327,"'USP17L17'",0,0.12,0,0.04,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0016787///hydrolase activity+++GO:0004197///cysteine-type endopeptidase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0042981///regulation of apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process","ubiquitin specific peptidase 17-like family member 17","[U17LH_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 17; EC=3.4.19.12;+++[A0A087WVW9_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 17 {ECO:0000313|Ensembl:ENSP00000479739};"]
[100287364,"'USP17L18'",0,0.12,0,0.04,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008234///cysteine-type peptidase activity","GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0042981///regulation of apoptotic process","ubiquitin specific peptidase 17-like family member 18","[U17LI_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 18; EC=3.4.19.12;+++[A0A087WTC1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 18 {ECO:0000313|Ensembl:ENSP00000477751};"]
[100287404,"'USP17L19'",0,0.12,0,0.04,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0006508///proteolysis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0042981///regulation of apoptotic process","ubiquitin specific peptidase 17-like family member 19","[U17LJ_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 19; EC=3.4.19.12;+++[A0A087WYD9_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 19 {ECO:0000313|Ensembl:ENSP00000481718};"]
[100287441,"'USP17L20'",0,0.12,0,0.04,{"$nulls":4},"GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum","GO:0004197///cysteine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008234///cysteine-type peptidase activity","GO:0016579///protein deubiquitination+++GO:0042981///regulation of apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006508///proteolysis","ubiquitin specific peptidase 17-like family member 20","[U17LK_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 20; EC=3.4.19.12;+++[A0A087WTF5_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 20 {ECO:0000313|Ensembl:ENSP00000477832};"]
[100287478,"'USP17L21'",0,0.12,0,0.04,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity","GO:0042981///regulation of apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006508///proteolysis+++GO:0016579///protein deubiquitination","ubiquitin specific peptidase 17-like family member 21","[U17LL_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 21; EC=3.4.19.12;+++[A0A087WUD4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 21 {ECO:0000313|Ensembl:ENSP00000478565};"]
[100287482,"'SMKR1'",6,9,12,9,{"$nulls":7},"small lysine rich protein 1","[SMKR1_HUMAN|Reviewed]RecName: Full=Small lysine-rich protein 1;"]
[100287513,"'USP17L22'",0,0.12,0,0.04,{"$nulls":4},"GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum","GO:0004197///cysteine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008234///cysteine-type peptidase activity","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0042981///regulation of apoptotic process+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","ubiquitin specific peptidase 17-like family member 22","[U17LM_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 22; EC=3.4.19.12;+++[A0A087WWE9_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 22 {ECO:0000313|Ensembl:ENSP00000480174};"]
[100287896,"'LOC100287896'",73,62,48,61,"04140///Autophagy - animal+++00785///Lipoic acid metabolism+++04137///Mitophagy - animal+++01100///Metabolic pathways",null,null,"R07769///lipoyl-[acp]:protein N6-lipoyltransferase Lipoyl-[acp] + Apoprotein <=> Protein N6-(lipoyl)lysine + Acyl-carrier protein+++R07766///octanoyl-[acp]:protein N6-octanoyltransferase Octanoyl-[acp] + Apoprotein <=> Protein N6-(octanoyl)lysine + Acyl-carrier protein","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0033819///lipoyl(octanoyl) transferase activity+++GO:0016874///ligase activity+++GO:0102555///octanoyl transferase activity (acting on glycine-cleavage complex H protein)","GO:0009249///protein lipoylation+++GO:0034641///cellular nitrogen compound metabolic process+++GO:2000376///positive regulation of oxygen metabolic process","uncharacterized LOC100287896","[Q8TB74_HUMAN|Unreviewed]SubName: Full=Similar to Cytochrome c, somatic {ECO:0000313|EMBL:AAH19340.1};"]
[100287898,"'TTC34'",8,15,15,12.6666666666667,{"$nulls":7},"tetratricopeptide repeat domain 34","[TTC34_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 34; Short=TPR repeat protein 34;+++[A0A1C7CYW7_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 34 {ECO:0000313|Ensembl:ENSP00000383873};"]
[100287932,"'TIMM23'",718.61,843.92,901.83,821.453333333333,"04212///Longevity regulating pathway - worm","H00032///Thyroid cancer",null,null,"GO:0016021///integral component of membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031305///integral component of mitochondrial inner membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport","translocase of inner mitochondrial membrane 23","[TIM23_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim23;+++[Q6X2S9_HUMAN|Unreviewed]SubName: Full=Translocase of the inner mitochondrial membrane {ECO:0000313|EMBL:AAP83315.1}; Flags: Fragment;"]
[100288142,"'NBPF20'",647.39,617.1,475.58,580.023333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0003723///RNA binding",null,"NBPF member 20","[NBPFK_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 20;+++[A0A075B7A3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000471335};+++[A0A087WU97_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000478481};+++[H7BY70_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000358380};"]
[100288332,"'NPIPA5'",265.05,286.88,317.35,289.76,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"nuclear pore complex interacting protein family member A5","[NPIA5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[A0A067ZUK6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28873.1}; Flags: Fragment;+++[A0A067ZUK7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28878.1}; Flags: Fragment;+++[A0A067ZUK9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28883.1}; Flags: Fragment;+++[A0A067ZUL0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28888.1}; Flags: Fragment;+++[A0A067ZUL2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28893.1}; Flags: Fragment;+++[A0A067ZUL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28898.1}; Flags: Fragment;+++[A0A067ZUL5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28903.1}; Flags: Fragment;+++[A0A067ZUL6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28908.1}; Flags: Fragment;+++[A0A067ZUL8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28913.1}; Flags: Fragment;+++[A0A067ZVG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28875.1}; Flags: Fragment;+++[A0A067ZVG5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28880.1}; Flags: Fragment;+++[A0A067ZVG8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28885.1}; Flags: Fragment;+++[A0A067ZVH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28890.1}; Flags: Fragment;+++[A0A067ZVH5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28895.1}; Flags: Fragment;+++[A0A067ZVH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28900.1}; Flags: Fragment;+++[A0A067ZVI1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28905.1}; Flags: Fragment;+++[A0A067ZVI6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28910.1}; Flags: Fragment;+++[A0A067ZWN6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28874.1}; Flags: Fragment;+++[A0A067ZWN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28879.1}; Flags: Fragment;+++[A0A067ZWP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28884.1}; Flags: Fragment;+++[A0A067ZWP4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28889.1}; Flags: Fragment;+++[A0A067ZWP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28894.1}; Flags: Fragment;+++[A0A067ZWQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28899.1}; Flags: Fragment;+++[A0A067ZWQ3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28904.1}; Flags: Fragment;+++[A0A067ZWQ8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28909.1}; Flags: Fragment;+++[A0A067ZWR0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28914.1}; Flags: Fragment;+++[A0A067ZXG0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28872.1}; Flags: Fragment;+++[A0A067ZXG1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28877.1}; Flags: Fragment;+++[A0A067ZXG4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28882.1}; Flags: Fragment;+++[A0A067ZXG6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28887.1}; Flags: Fragment;+++[A0A067ZXG7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28892.1}; Flags: Fragment;+++[A0A067ZXH0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28897.1}; Flags: Fragment;+++[A0A067ZXH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28902.1}; Flags: Fragment;+++[A0A067ZXH4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28907.1}; Flags: Fragment;+++[A0A067ZXH7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28912.1}; Flags: Fragment;+++[A0A067ZXH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28917.1}; Flags: Fragment;+++[A0A067ZXM6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28876.1}; Flags: Fragment;+++[A0A067ZXN0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28881.1}; Flags: Fragment;+++[A0A067ZXN4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28886.1}; Flags: Fragment;+++[A0A067ZXN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28891.1}; Flags: Fragment;+++[A0A067ZXP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28896.1}; Flags: Fragment;+++[A0A067ZXP5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28901.1}; Flags: Fragment;+++[A0A067ZXP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28906.1}; Flags: Fragment;+++[A0A067ZXQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28911.1}; Flags: Fragment;+++[A0A0B4J1W7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000389275};+++[A0A0J9YW65_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000487831}; Flags: Fragment;+++[A0A0J9YWV6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000488135};+++[E9PJ88_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435611};+++[H0YED6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435610}; Flags: Fragment;+++[H0YEP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000436257}; Flags: Fragment;+++[H0YF59_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000437314}; Flags: Fragment;+++[Q9NRE7_HUMAN|Unreviewed]SubName: Full=KIAA0220-like protein {ECO:0000313|EMBL:AAF82267.1}; SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000330634};"]
[100288413,"'ERVMER34-1'",104,110,105,106.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region",null,null,"endogenous retrovirus group MER34 member 1, envelope","[MER34_HUMAN|Reviewed]RecName: Full=Endogenous retroviral envelope protein HEMO {ECO:0000305}; AltName: Full=Endogenous retrovirus group MER34 member 1 Env polyprotein {ECO:0000305}; AltName: Full=HERV-MER_4q12 provirus ancestral Env polyprotein; AltName: Full=Human endogenous MER34 (medium-reiteration-frequency-family-34) open reading frame {ECO:0000303|PubMed:28739914}; AltName: Full=Human endogenous MER34 ORF {ECO:0000303|PubMed:28739914}; Short=HEMO {ECO:0000303|PubMed:28739914}; Contains: RecName: Full=Endogenous retroviral envelope protein HEMO, secreted form {ECO:0000305}; AltName: Full=Endogenous retroviral envelope protein HEMO, 48 kDa form; Flags: Precursor;"]
[100288687,"'DUX4'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005829///cytosol","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0008285///negative regulation of cell proliferation+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0006351///transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II","double homeobox 4","[DUX4_HUMAN|Reviewed]RecName: Full=Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}; AltName: Full=Double homeobox protein 10 {ECO:0000312|EMBL:AAK91509.1};+++[A0A2H4V0R9_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:AUA60622.1};+++[C3U395_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACN62209.1};+++[C3U396_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30487.1};+++[C3U397_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30488.1};+++[C3U398_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACN62210.1};+++[C3U399_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30489.1};+++[C3U3A0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ACP30490.1}; SubName: Full=Double homeodomain protein DUX4-fl {ECO:0000313|EMBL:ADN68615.1};+++[E0YLM6_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK45392.1}; Flags: Fragment;+++[E0Z3E7_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24689.1};+++[E0Z3E8_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24690.1};+++[E0Z3E9_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24691.1};+++[E0Z3F0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24692.1};+++[E0Z3F1_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24693.1};+++[E0Z3F3_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24695.1}; SubName: Full=DUX4L {ECO:0000313|EMBL:AUA60219.1}; Flags: Fragment;+++[E0Z3F7_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24699.1}; Flags: Fragment;+++[E0Z3G4_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24706.1};+++[E0Z3H0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24712.1};+++[E0Z3H2_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24714.1};+++[E0Z3H5_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24717.1};+++[E2JJS1_HUMAN|Unreviewed]SubName: Full=Double homeobox protein 4 {ECO:0000313|Ensembl:ENSP00000455112}; SubName: Full=Double homeodomain protein DUX4-s {ECO:0000313|EMBL:ADN68617.1};+++[F8QWT8_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24684.1};+++[F8QWU0_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24685.1};+++[F8QWU1_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24683.1};+++[F8QWU2_HUMAN|Unreviewed]SubName: Full=DUX4 {ECO:0000313|EMBL:ADK24688.1};"]
[100288695,"'LIMS4'",26.6,37.35,17.95,27.3,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0045216///cell-cell junction organization","LIM zinc finger domain containing 4","[LIMS3_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 3; AltName: Full=Particularly interesting new Cys-His protein 3; Short=PINCH-3;+++[LIMS4_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 4; AltName: Full=LIM and senescent cell antigen-like-containing domain protein 3-like;+++[A0A0J9YXC7_HUMAN|Unreviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein {ECO:0000256|PIRNR:PIRNR038003};"]
[100288801,"'FRG2C'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0019843///rRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0045296///cadherin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006413///translational initiation+++GO:0008283///cell proliferation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000027///ribosomal large subunit assembly+++GO:0045766///positive regulation of angiogenesis+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001570///vasculogenesis+++GO:0006412///translation+++GO:0007155///cell adhesion","FSHD region gene 2 family member C","[FRG2C_HUMAN|Reviewed]RecName: Full=Protein FRG2-like-2; AltName: Full=FSHD region gene 2 protein family member C; AltName: Full=HSA3-FRG2;+++[C9JUX3_HUMAN|Unreviewed]SubName: Full=Protein FRG2-like-2 {ECO:0000313|Ensembl:ENSP00000419432};"]
[100288960,"'PRSS43'",3,2,3,2.66666666666667,"04137///Mitophagy - animal+++05410///Hypertrophic cardiomyopathy (HCM)+++04261///Adrenergic signaling in cardiomyocytes+++04371///Apelin signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04140///Autophagy - animal+++04260///Cardiac muscle contraction","H00292///Hypertrophic cardiomyopathy (HCM)",null,null,"GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006508///proteolysis","serine protease 43","[PRS43_HUMAN|Reviewed]RecName: Full=Putative inactive serine protease 43 {ECO:0000305}; Flags: Precursor;"]
[100289187,"'TMEM225B'",2,1,3.8,2.26666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0010923///negative regulation of phosphatase activity","transmembrane protein 225B","[T225B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 225B {ECO:0000312|HGNC:HGNC:53075};"]
[100289279,"'CNTNAP3C'",72.73,67.24,54.39,64.7866666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region",null,"GO:0008037///cell recognition+++GO:0007155///cell adhesion","contactin associated protein like 3C","[CNT3B_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3B; AltName: Full=Cell recognition molecule Caspr3b; Flags: Precursor;+++[CNTP3_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3; AltName: Full=Cell recognition molecule Caspr3; Flags: Precursor;+++[CNTP4_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP4_MOUSE|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP5_CHICK|diamond]RecName: Full=Contactin-associated protein-like 5; AltName: Full=Cell recognition molecule Caspr5; Flags: Precursor;"]
[100289561,"'LOC100289561'",91.59,119.35,97.09,102.676666666667,{"$nulls":4},"GO:0032389///MutLalpha complex","GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding","GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0006298///mismatch repair+++GO:0006355///regulation of transcription, DNA-templated","uncharacterized LOC100289561","[PM2P3_HUMAN|diamond]RecName: Full=Putative postmeiotic segregation increased 2-like protein 3; AltName: Full=PMS2-related protein 3; AltName: Full=Postmeiotic segregation increased 2-like protein 9; AltName: Full=Postmeiotic segregation increased protein 5; AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 3;+++[RBAK_HUMAN|diamond]RecName: Full=RB-associated KRAB zinc finger protein; AltName: Full=RB-associated KRAB repressor; Short=hRBaK; AltName: Full=Zinc finger protein 769;+++[ZN510_HUMAN|diamond]RecName: Full=Zinc finger protein 510;+++[ZNF12_HUMAN|diamond]RecName: Full=Zinc finger protein 12; AltName: Full=Gonadotropin-inducible ovary transcription repressor 3; Short=GIOT-3; AltName: Full=Zinc finger protein 325; AltName: Full=Zinc finger protein KOX3;+++[ZNF12_MOUSE|diamond]RecName: Full=Zinc finger protein 12;"]
[100289635,"'ZNF605'",335,334,278,315.666666666667,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 605","[ZN605_HUMAN|Reviewed]RecName: Full=Zinc finger protein 605;+++[Q8WW51_HUMAN|Unreviewed]SubName: Full=ZNF605 protein {ECO:0000313|EMBL:AAH20877.1}; Flags: Fragment;"]
[100289678,"'ZNF783'",164,153.33,150,155.776666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger family member 783","[ZN783_HUMAN|Reviewed]RecName: Full=Protein ZNF783;"]
[100293516,"'ZNF587B'",33.39,30.95,30.3,31.5466666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 587B","[Z587B_HUMAN|Reviewed]RecName: Full=Zinc finger protein 587B;+++[M0QY62_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000469623};+++[M0R1N2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000472004}; Flags: Fragment;"]
[100293534,"'C4B_2'",498.08,148.07,442.57,362.906666666667,"05150///Staphylococcus aureus infection+++05322///Systemic lupus erythematosus+++05133///Pertussis+++04610///Complement and coagulation cascades","H00102///Classic complement pathway component defects+++H00080///Systemic lupus erythematosus+++H01649///Schizophrenia",null,null,"GO:0030054///cell junction+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0030424///axon+++GO:0030425///dendrite+++GO:0072562///blood microparticle+++GO:0043025///neuronal cell body+++GO:0005886///plasma membrane+++GO:0044216///other organism cell","GO:0001848///complement binding+++GO:0030246///carbohydrate binding+++GO:0004252///serine-type endopeptidase activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0001849///complement component C1q binding","GO:2000427///positive regulation of apoptotic cell clearance+++GO:0043687///post-translational protein modification+++GO:0008228///opsonization+++GO:0030449///regulation of complement activation+++GO:0032490///detection of molecule of bacterial origin+++GO:0044267///cellular protein metabolic process+++GO:0006954///inflammatory response+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response+++GO:0006956///complement activation","complement component 4B (Chido blood group), copy 2","[CO4B_HUMAN|Reviewed]RecName: Full=Complement C4-B; AltName: Full=Basic complement C4; AltName: Full=C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; Contains: RecName: Full=Complement C4 beta chain; Contains: RecName: Full=Complement C4-B alpha chain; Contains: RecName: Full=C4a anaphylatoxin; Contains: RecName: Full=C4b-B; Contains: RecName: Full=C4d-B; Contains: RecName: Full=Complement C4 gamma chain; Flags: Precursor;+++[A0A0G2JL54_HUMAN|Unreviewed]SubName: Full=Complement C4-B {ECO:0000313|Ensembl:ENSP00000449433};"]
[100302652,"'GPR75-ASB3'",68.82,61.12,44.95,58.2966666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0035556///intracellular signal transduction+++GO:0016567///protein ubiquitination","GPR75-ASB3 readthrough","[ASB3_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 3; Short=ASB-3;+++[A0A0A6YYF3_HUMAN|Unreviewed]SubName: Full=Protein GPR75-ASB3 {ECO:0000313|Ensembl:ENSP00000385085};"]
[100302736,"'TMED7-TICAM2'",85.99,84.42,88.17,86.1933333333333,"05161///Hepatitis B+++04620///Toll-like receptor signaling pathway+++05133///Pertussis+++04064///NF-kappa B signaling pathway+++04217///Necroptosis",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030134///COPII-coated ER to Golgi transport vesicle","GO:0005543///phospholipid binding","GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization","TMED7-TICAM2 readthrough","[TCAM2_HUMAN|Reviewed]RecName: Full=TIR domain-containing adapter molecule 2; Short=TICAM-2; AltName: Full=Putative NF-kappa-B-activating protein 502; AltName: Full=TRIF-related adapter molecule; AltName: Full=Toll-like receptor adaptor protein 3; AltName: Full=Toll/interleukin-1 receptor domain-containing protein; Short=MyD88-4;+++[TMED7_HUMAN|Reviewed]RecName: Full=Transmembrane emp24 domain-containing protein 7; AltName: Full=p24 family protein gamma-3; Short=p24gamma3; AltName: Full=p27; Flags: Precursor;+++[A0A0A6YYA0_HUMAN|Unreviewed]SubName: Full=Protein TMED7-TICAM2 {ECO:0000313|Ensembl:ENSP00000333650};"]
[100303755,"'PET117'",56.32,53.89,83.51,64.5733333333333,{"$nulls":4},"GO:0005739///mitochondrion","GO:0004402///histone acetyltransferase activity+++GO:0030274///LIM domain binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","PET117 homolog","[PT117_HUMAN|Reviewed]RecName: Full=Protein PET117 homolog, mitochondrial; Flags: Precursor;+++[L0R6F6_HUMAN|Unreviewed]SubName: Full=Alternative protein CSRP2BP {ECO:0000313|EMBL:CCO13715.1};"]
[100310812,"'SPDYE2B'",0,3,1.86,1.62,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",null,null,"GO:0005737///cytoplasm+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane+++GO:0005829///cytosol","GO:0019901///protein kinase binding","GO:0046580///negative regulation of Ras protein signal transduction+++GO:0034260///negative regulation of GTPase activity+++GO:0045859///regulation of protein kinase activity+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0071277///cellular response to calcium ion","speedy/RINGO cell cycle regulator family member E2B","[SPE2B_HUMAN|Reviewed]RecName: Full=Speedy protein E2B;"]
[100316904,"'SAP25'",11,12,7,10,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0006355///regulation of transcription, DNA-templated","Sin3A associated protein 25","[SAP25_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP25; AltName: Full=25 kDa Sin3-associated polypeptide; AltName: Full=Sin3 corepressor complex subunit SAP25;+++[A0A087WYF9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP25 {ECO:0000313|Ensembl:ENSP00000481773};"]
[10036,"'CHAF1A'",149,146,161,152,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0033186///CAF-1 complex","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0070087///chromo shadow domain binding+++GO:0051082///unfolded protein binding+++GO:0003682///chromatin binding","GO:0031497///chromatin assembly+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006334///nucleosome assembly+++GO:0007049///cell cycle","chromatin assembly factor 1 subunit A","[CAF1A_HUMAN|Reviewed]RecName: Full=Chromatin assembly factor 1 subunit A; Short=CAF-1 subunit A; AltName: Full=Chromatin assembly factor I p150 subunit; Short=CAF-I 150 kDa subunit; Short=CAF-I p150; Short=hp150;+++[D6W625_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1, subunit A (P150), isoform CRA_a {ECO:0000313|EMBL:EAW69225.1};+++[K7EJF1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000465142}; Flags: Fragment;+++[K7EME9_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466475}; Flags: Fragment;+++[K7ENC7_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466888}; Flags: Fragment;+++[K7EPA1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000467296}; Flags: Fragment;"]
[10038,"'PARP2'",290,274,256,273.333333333333,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04210///Apoptosis+++04212///Longevity regulating pathway - worm",null,"M00296///BER complex",null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990404///protein ADP-ribosylase activity","GO:0006471///protein ADP-ribosylation+++GO:0006281///DNA repair+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0018312///peptidyl-serine ADP-ribosylation+++GO:1901215///negative regulation of neuron death","poly(ADP-ribose) polymerase 2","[PARP2_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 2; Short=PARP-2; Short=hPARP-2; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 2; Short=ARTD2; AltName: Full=NAD(+) ADP-ribosyltransferase 2; Short=ADPRT-2; AltName: Full=Poly[ADP-ribose] synthase 2; Short=pADPRT-2;+++[E9PJ27_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 2 {ECO:0000313|Ensembl:ENSP00000431867};+++[G3V167_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[H0YH02_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114}; Flags: Fragment;"]
[100381270,"'ZBED6'",174,169,57,133.333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger BED-type containing 6","[ZBED6_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 6 {ECO:0000303|PubMed:20016685};"]
[10039,"'PARP3'",360,394,417,390.333333333333,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04212///Longevity regulating pathway - worm+++04210///Apoptosis",null,"M00296///BER complex",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0005815///microtubule organizing center+++GO:0005730///nucleolus+++GO:0005814///centriole+++GO:0005856///cytoskeleton","GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003824///catalytic activity+++GO:0016740///transferase activity","GO:0051106///positive regulation of DNA ligation+++GO:0060236///regulation of mitotic spindle organization+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0006281///DNA repair+++GO:1905662///negative regulation of telomerase RNA reverse transcriptase activity+++GO:0000723///telomere maintenance+++GO:0006471///protein ADP-ribosylation+++GO:1990166///protein localization to site of double-strand break","poly(ADP-ribose) polymerase family member 3","[PARP3_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 3; Short=PARP-3; Short=hPARP-3; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 3; Short=ARTD3; AltName: Full=IRT1; AltName: Full=NAD(+) ADP-ribosyltransferase 3; Short=ADPRT-3; AltName: Full=Poly[ADP-ribose] synthase 3; Short=pADPRT-3;+++[A0A024R2X5_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[C9J9C7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417625}; Flags: Fragment;+++[F8WAY7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417396};"]
[1004,"'CDH6'",115,192,143,150,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0009986///cell surface+++GO:0016342///catenin complex+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0034332///adherens junction organization","cadherin 6","[CADH6_HUMAN|Reviewed]RecName: Full=Cadherin-6; AltName: Full=Kidney cadherin; Short=K-cadherin; Flags: Precursor;+++[D6RF86_HUMAN|Unreviewed]SubName: Full=Cadherin-6 {ECO:0000313|Ensembl:ENSP00000424843};+++[L8EAC6_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH6 {ECO:0000313|EMBL:CCQ43288.1};"]
[10040,"'TOM1L1'",558,503,473,511.333333333333,"04714///Thermogenesis+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++04137///Mitophagy - animal+++04140///Autophagy - animal",null,"M00154///Cytochrome c oxidase",null,"GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005623///cell+++GO:0005795///Golgi stack+++GO:0005768///endosome+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0043130///ubiquitin binding+++GO:0005515///protein binding+++GO:0030295///protein kinase activator activity+++GO:0017124///SH3 domain binding","GO:0006886///intracellular protein transport+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:2000278///regulation of DNA biosynthetic process+++GO:0015031///protein transport+++GO:0031954///positive regulation of protein autophosphorylation","target of myb1 like 1 membrane trafficking protein","[TM1L1_HUMAN|Reviewed]RecName: Full=TOM1-like protein 1; AltName: Full=Src-activating and signaling molecule protein; AltName: Full=Target of Myb-like protein 1;+++[I3L0N2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458219};+++[I3L1G1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458809}; Flags: Fragment;+++[I3L1Q1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459003}; Flags: Fragment;+++[I3L1T2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459079};+++[I3L367_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460213}; Flags: Fragment;+++[I3L3M3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460565};+++[I3L3T4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460721};+++[I3L4G0_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461215}; Flags: Fragment;+++[I3L4I4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461284};+++[I3L4N3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461396}; Flags: Fragment;+++[I3NI44_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461876};+++[J3KQU4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000408958}; SubName: Full=Target of myb1-like 1 (Chicken), isoform CRA_b {ECO:0000313|EMBL:EAW94552.1};+++[K7EP47_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000467227}; Flags: Fragment;+++[Q8NI65_HUMAN|Unreviewed]SubName: Full=OK/KNS-CL.3 {ECO:0000313|EMBL:BAB93522.1};"]
[10042,"'HMGXB4'",313,290,208,270.333333333333,{"$nulls":4},"GO:0016589///NURF complex+++GO:0005634///nucleus","GO:0003677///DNA binding","GO:0016055///Wnt signaling pathway+++GO:0008333///endosome to lysosome transport+++GO:0030178///negative regulation of Wnt signaling pathway","HMG-box containing 4","[HMGX4_HUMAN|Reviewed]RecName: Full=HMG domain-containing protein 4; AltName: Full=HMG box-containing protein 4; AltName: Full=High mobility group protein 2-like 1; AltName: Full=Protein HMGBCG;+++[B0QXZ8_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000415500}; Flags: Fragment;+++[B0QXZ9_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000401658}; Flags: Fragment;+++[F8WDU7_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000395532};+++[Q2M3X1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI04757.1}; SubName: Full=High-mobility group protein 2-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW60048.1};+++[Q2T9L2_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI11374.1}; Flags: Fragment;+++[Q6P681_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH62413.1}; Flags: Fragment;+++[Q6PJ09_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH25303.1}; Flags: Fragment;+++[Q6PJC1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH17326.1}; Flags: Fragment;+++[Q7Z641_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH52624.1}; Flags: Fragment;"]
[10043,"'TOM1'",1630,1601,1727,1652.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0005769///early endosome+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005623///cell+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0035577///azurophil granule membrane","GO:0030276///clathrin binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0043312///neutrophil degranulation+++GO:0016197///endosomal transport+++GO:0006897///endocytosis","target of myb1 membrane trafficking protein","[TOM1_HUMAN|Reviewed]RecName: Full=Target of Myb protein 1;+++[B0QY01_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000393714}; Flags: Fragment;+++[B0QY02_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000389789}; Flags: Fragment;+++[B3KUF5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39747 fis, clone SMINT2017432, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53417.1};+++[B3KUU1_HUMAN|Unreviewed]SubName: Full=Target of myb1 (Chicken), isoform CRA_a {ECO:0000313|EMBL:EAW60053.1}; SubName: Full=cDNA FLJ40607 fis, clone THYMU2012273, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53553.1};+++[F8WAW7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000385906};+++[F8WB30_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000397492};+++[F8WBB0_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000390429};+++[F8WE29_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000394944};+++[H7BYN7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000379085};+++[Q6UW50_HUMAN|Unreviewed]SubName: Full=TOM1 {ECO:0000313|EMBL:AAQ89339.1}; SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000371465};+++[V9GYF4_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000476698}; Flags: Fragment;+++[V9GZ68_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000477471}; Flags: Fragment;"]
[10044,"'SH2D3C'",7,21,10,12.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0098793///presynapse+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004102///choline O-acetyltransferase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005070///SH3/SH2 adaptor activity","GO:0007254///JNK cascade+++GO:0007269///neurotransmitter secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0008292///acetylcholine biosynthetic process+++GO:0009967///positive regulation of signal transduction+++GO:0007274///neuromuscular synaptic transmission+++GO:0007264///small GTPase mediated signal transduction+++GO:0042136///neurotransmitter biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process","SH2 domain containing 3C","[SH2D3_HUMAN|Reviewed]RecName: Full=SH2 domain-containing protein 3C; AltName: Full=Novel SH2-containing protein 3; AltName: Full=SH2 domain-containing Eph receptor-binding protein 1; Short=SHEP1;+++[A0A1W2PP46_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000491328};+++[A0A1W2PRG4_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000492646};+++[B4DG32_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59318, highly similar to SH2 domain-containing protein 3C {ECO:0000313|EMBL:BAG57643.1};+++[H0Y5X5_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3C {ECO:0000313|Ensembl:ENSP00000401641}; Flags: Fragment;+++[Q5JU32_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3C {ECO:0000313|Ensembl:ENSP00000413760}; Flags: Fragment;+++[R4GN13_HUMAN|Unreviewed]SubName: Full=Choline O-acetyltransferase {ECO:0000313|Ensembl:ENSP00000473443};"]
[10045,"'SH2D3A'",23,28,18,23,"04910///Insulin signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0005622///intracellular+++GO:0005764///lysosome+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0005794///Golgi apparatus+++GO:0001891///phagocytic cup","GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005070///SH3/SH2 adaptor activity","GO:0007254///JNK cascade+++GO:0007264///small GTPase mediated signal transduction+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0009967///positive regulation of signal transduction","SH2 domain containing 3A","[SH23A_HUMAN|Reviewed]RecName: Full=SH2 domain-containing protein 3A; AltName: Full=Novel SH2-containing protein 1;+++[A8K2M8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78700, highly similar to Homo sapiens SH2 domain containing 3A, mRNA {ECO:0000313|EMBL:BAF82982.1};+++[M0QZQ6_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000470700}; Flags: Fragment;"]
[10046,"'MAMLD1'",953,667,633,751,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00609///46,XY disorders of sex development (Other)",null,null,"GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008584///male gonad development","mastermind like domain containing 1","[MAMD1_HUMAN|Reviewed]RecName: Full=Mastermind-like domain-containing protein 1; AltName: Full=F18; AltName: Full=Protein CG1;+++[F8WAK3_HUMAN|Unreviewed]SubName: Full=Mastermind-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000351765}; Flags: Fragment;+++[L0R6K4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAMLD1 {ECO:0000313|EMBL:CCO13767.1};"]
[100462977,"'MTRNR2L1'",1716.02,1792,2472.93,1993.65,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 1","[HMN1_HUMAN|Reviewed]RecName: Full=Humanin-like 1 {ECO:0000305}; Short=HN1 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 1 {ECO:0000312|HGNC:HGNC:37155};"]
[100462981,"'MTRNR2L2'",108479.54,109048.74,126269.59,114599.29,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 2","[HMN2_HUMAN|Reviewed]RecName: Full=Humanin-like 2 {ECO:0000305}; Short=HN2 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 2 {ECO:0000312|HGNC:HGNC:37156};"]
[100462983,"'MTRNR2L3'",524.76,527.46,530.8,527.673333333333,"03013///RNA transport+++05164///Influenza A",null,"M00427///Nuclear pore complex",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 3","[HMN3_HUMAN|Reviewed]RecName: Full=Humanin-like 3 {ECO:0000305}; Short=HN3 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 3 {ECO:0000312|HGNC:HGNC:37157};"]
[100463482,"'MTRNR2L6'",420.07,384.85,632.79,479.236666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 6","[HMN6_HUMAN|Reviewed]RecName: Full=Humanin-like 6 {ECO:0000305}; Short=HN6 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 6 {ECO:0000312|HGNC:HGNC:37163};"]
[100463486,"'MTRNR2L8'",63278.43,63781.43,64561.28,63873.7133333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","MT-RNR2 like 8","[HMN8_HUMAN|Reviewed]RecName: Full=Humanin-like 8 {ECO:0000305}; Short=HN8 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 8 {ECO:0000312|HGNC:HGNC:37165};"]
[100463487,"'MTRNR2L9'",830.18,808.97,1104.4,914.516666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","MT-RNR2 like 9","[HMN9_HUMAN|Reviewed]RecName: Full=Humanin-like 9 {ECO:0000305}; Short=HN9 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 9 {ECO:0000312|HGNC:HGNC:37166};"]
[100463488,"'MTRNR2L10'",292.99,311.55,380.21,328.25,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","MT-RNR2 like 10","[HMN10_HUMAN|Reviewed]RecName: Full=Humanin-like 10 {ECO:0000305}; Short=HN10 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 10 {ECO:0000312|HGNC:HGNC:37167};"]
[10047,"'CST8'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0005576///extracellular region","GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity","cystatin 8","[CST8_HUMAN|Reviewed]RecName: Full=Cystatin-8; AltName: Full=Cystatin-related epididymal spermatogenic protein; Flags: Precursor;+++[A2A2N0_HUMAN|Unreviewed]RecName: Full=Cystatin {ECO:0000256|RuleBase:RU362130}; Flags: Fragment;"]
[10048,"'RANBP9'",983,1039,840,954,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex","GO:0019899///enzyme binding+++GO:0008536///Ran GTPase binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007020///microtubule nucleation+++GO:0007411///axon guidance+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000165///MAPK cascade","RAN binding protein 9","[RANB9_HUMAN|Reviewed]RecName: Full=Ran-binding protein 9; Short=RanBP9; AltName: Full=BPM-L; AltName: Full=BPM90; AltName: Full=Ran-binding protein M; Short=RanBPM {ECO:0000303|PubMed:11470507, ECO:0000303|PubMed:17467196}; AltName: Full=RanBP7;+++[A0A024QZW3_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_a {ECO:0000313|EMBL:EAW55345.1};+++[A0A024R014_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_b {ECO:0000313|EMBL:EAW55344.1};"]
[10049,"'DNAJB6'",1463,1721,1693,1625.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0031072///heat shock protein binding+++GO:0001671///ATPase activator activity+++GO:0042802///identical protein binding+++GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0060710///chorio-allantoic fusion+++GO:0032781///positive regulation of ATPase activity+++GO:1900034///regulation of cellular response to heat+++GO:0060715///syncytiotrophoblast cell differentiation involved in labyrinthine layer development+++GO:0090084///negative regulation of inclusion body assembly+++GO:0030198///extracellular matrix organization+++GO:0030036///actin cytoskeleton organization+++GO:0006457///protein folding+++GO:0045109///intermediate filament organization+++GO:0060717///chorion development+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated","DnaJ heat shock protein family (Hsp40) member B6","[DNJB6_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily B member 6; AltName: Full=HHDJ1; AltName: Full=Heat shock protein J2; Short=HSJ-2; AltName: Full=MRJ; AltName: Full=MSJ-1;+++[A0A0J9YX62_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000488263};+++[C9J2C4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000400665}; Flags: Fragment;+++[C9J2P2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000410643}; Flags: Fragment;+++[C9JB42_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000391690}; Flags: Fragment;+++[C9JDR7_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396240}; Flags: Fragment;+++[C9JDX6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000403407}; Flags: Fragment;+++[C9JN01_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000389599}; Flags: Fragment;+++[E9PH18_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396267};+++[F8WCZ4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000415201};+++[Q49A72_HUMAN|Unreviewed]SubName: Full=DNAJB6 protein {ECO:0000313|EMBL:AAH43270.1};+++[Q75MP3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DNAJB6 {ECO:0000313|EMBL:AAS07521.1}; Flags: Fragment;"]
[100499483,"'CCDC180'",104,82,102,96,{"$nulls":4},"GO:0070062///extracellular exosome",null,null,"coiled-coil domain containing 180","[CC180_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 180;+++[B4DZK1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50036, weakly similar to Myosin-11 {ECO:0000313|EMBL:BAG64113.1};"]
[100500938,"'CCDC179'",0,2,0,0.666666666666667,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005911///cell-cell junction+++GO:0005654///nucleoplasm+++GO:0005912///adherens junction+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0001533///cornified envelope+++GO:0030054///cell junction+++GO:0005882///intermediate filament+++GO:0005634///nucleus+++GO:0030057///desmosome","GO:0086083///cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication+++GO:0044325///ion channel binding+++GO:0045296///cadherin binding+++GO:0019215///intermediate filament binding+++GO:0045294///alpha-catenin binding+++GO:0017080///sodium channel regulator activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0005080///protein kinase C binding","GO:0031424///keratinization+++GO:0048496///maintenance of animal organ identity+++GO:0045110///intermediate filament bundle assembly+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0002159///desmosome assembly+++GO:0098609///cell-cell adhesion+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0007507///heart development+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086019///cell-cell signaling involved in cardiac conduction+++GO:0072659///protein localization to plasma membrane+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0010765///positive regulation of sodium ion transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:0070268///cornification","coiled-coil domain containing 179","[CC179_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 179;"]
[100505385,"'IQCJ-SCHIP1'",939.13,884.26,876.3,899.896666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0043194///axon initial segment+++GO:0030424///axon","GO:0005515///protein binding","GO:0051494///negative regulation of cytoskeleton organization","IQCJ-SCHIP1 readthrough","[IQIP1_HUMAN|Reviewed]RecName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000312|HGNC:HGNC:38842};+++[A0A1W2PP08_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491220}; Flags: Fragment;+++[A0A1W2PPY3_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491419}; Flags: Fragment;+++[A0A1W2PQT1_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492132}; Flags: Fragment;+++[A0A1W2PR78_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492358}; Flags: Fragment;+++[A0A1W2PR91_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492497}; Flags: Fragment;+++[A0A1W2PRV6_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492461}; Flags: Fragment;+++[A0A1W2PRY4_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492853}; Flags: Fragment;+++[C9J366_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000417305};"]
[100505549,"'LOC100505549'",9,8,8,8.33333333333333,{"$nulls":7},"uncharacterized LOC100505549","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100505573,"'INAFM2'",523,391,502,472,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005246///calcium channel regulator activity",null,"InaF motif containing 2","[INAM2_HUMAN|Reviewed]RecName: Full=Putative transmembrane protein INAFM2 {ECO:0000305}; AltName: Full=InaF-motif-containing protein 2 {ECO:0000312|HGNC:HGNC:35165}; AltName: Full=Osteogenesis up-regulated transcript 1 {ECO:0000303|PubMed:19531736};"]
[100505591,"'LRRC3C'",1,3,4,2.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space","GO:0043565///sequence-specific DNA binding+++GO:0004860///protein kinase inhibitor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0043312///neutrophil degranulation+++GO:0090156///cellular sphingolipid homeostasis+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0006672///ceramide metabolic process+++GO:1900060///negative regulation of ceramide biosynthetic process+++GO:0006351///transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0019221///cytokine-mediated signaling pathway","leucine rich repeat containing 3C","[LRR3C_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 3C; Flags: Precursor;"]
[100505679,"'UBE2Q2L'",5,0,0,1.66666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031258///lamellipodium membrane+++GO:0070062///extracellular exosome+++GO:0005925///focal adhesion+++GO:0005796///Golgi lumen+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0043202///lysosomal lumen","GO:0019901///protein kinase binding","GO:0030206///chondroitin sulfate biosynthetic process+++GO:0048771///tissue remodeling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030207///chondroitin sulfate catabolic process+++GO:0035556///intracellular signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001525///angiogenesis+++GO:0000187///activation of MAPK activity+++GO:0008283///cell proliferation+++GO:0008347///glial cell migration","ubiquitin conjugating enzyme E2 Q2 like","[U2Q2L_HUMAN|Reviewed]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;"]
[100505741,"'SPATA1'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005764///lysosome","GO:0008061///chitin binding+++GO:0004568///chitinase activity","GO:0009313///oligosaccharide catabolic process+++GO:0006032///chitin catabolic process","spermatogenesis associated 1","[SPAT1_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 1; AltName: Full=Sperm-specific protein SP-2;"]
[100505767,"'SPDYE18'",3,1,4,2.66666666666667,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E18","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPDE7_HUMAN|diamond]RecName: Full=Putative speedy protein E7; AltName: Full=Speedy protein E7 pseudogene;+++[SPDL3_HUMAN|diamond]RecName: Full=Putative speedy protein-like protein 3;"]
[100505841,"'LOC100505841'",6,0,0,2,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding",null,"zinc finger protein 474-like","[A0A1B0GTH9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000489710};+++[A0A1B0GW86_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490823}; Flags: Fragment;+++[A0A1B0GWJ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490947};"]
[100505876,"'CEBPZOS'",565,496.47,533.54,531.67,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","CEBPZ opposite strand","[CEBOS_HUMAN|Reviewed]RecName: Full=Protein CEBPZOS {ECO:0000305}; AltName: Full=CEBPZ antisense RNA 1 {ECO:0000312|HGNC:HGNC:49288}; AltName: Full=CEBPZ opposite strand {ECO:0000312|HGNC:HGNC:49288};"]
[100505989,"'SMIM31'",2.62,4,0.44,2.35333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"small integral membrane protein 31","[SIM31_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 31 {ECO:0000305};"]
[100505993,"'TMEM210'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 210","[TM210_HUMAN|Reviewed]RecName: Full=Transmembrane protein 210; Flags: Precursor;+++[H3BNS5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 210 {ECO:0000313|Ensembl:ENSP00000454984};"]
[100506012,"'PPP5D1'",13,14,25,17.3333333333333,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005622///intracellular","GO:0005509///calcium ion binding","GO:0019722///calcium-mediated signaling","PPP5 tetratricopeptide repeat domain containing 1","[PP5D1_HUMAN|Reviewed]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[A0A087WY80_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000481586}; Flags: Fragment;+++[M0R196_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000471730}; Flags: Fragment;"]
[100506084,"'ARL17B'",73.51,75.85,67.91,72.4233333333333,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport","ADP ribosylation factor like GTPase 17B","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[A8K0M5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76374 {ECO:0000313|EMBL:BAF82279.1};+++[I3L1A0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000458681}; Flags: Fragment;+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L2E4_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459606};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};+++[Q9BVU5_HUMAN|Unreviewed]SubName: Full=ARL17 protein {ECO:0000313|EMBL:AAH00924.2}; Flags: Fragment;"]
[100506115,"'SMIM25'",52,37,42,43.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"small integral membrane protein 25","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100506127,"'GVQW3'",71.52,92.8,75.83,80.05,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding","GO:0008285///negative regulation of cell proliferation+++GO:0007165///signal transduction","GVQW motif containing 3","[GVQW3_HUMAN|Reviewed]RecName: Full=Protein GVQW3 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 3 {ECO:0000305};+++[A0A0U1RQW1_HUMAN|Unreviewed]SubName: Full=Protein GVQW3 {ECO:0000313|Ensembl:ENSP00000489195};"]
[100506144,"'TMEM35B'",215,189,206,203.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 35B","[TM35B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 35B; AltName: Full=ZMYM6 neighbor protein; Flags: Precursor;"]
[100506164,"'HSFX1'",18,9,14,13.6666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0061408///positive regulation of transcription from RNA polymerase II promoter in response to heat stress+++GO:0006355///regulation of transcription, DNA-templated+++GO:0034605///cellular response to heat","heat shock transcription factor family, X-linked 1","[HSFX1_HUMAN|Reviewed]RecName: Full=Heat shock transcription factor, X-linked;+++[A0A140VK21_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 21 {ECO:0000313|EMBL:AEE61158.1};"]
[100506243,"'KRBOX1'",22,34,37,31,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","KRAB box domain containing 1","[KRBX1_HUMAN|Reviewed]RecName: Full=KRAB domain-containing protein 1;+++[A0A024R2N1_HUMAN|Unreviewed]SubName: Full=HCG2039480, isoform CRA_a {ECO:0000313|EMBL:EAW64687.1};"]
[100506248,"'PTMAP9'",550.42,622.07,585.77,586.086666666667,"05169///Epstein-Barr virus infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0042393///histone binding+++GO:0033613///activating transcription factor binding","GO:0043486///histone exchange+++GO:0006351///transcription, DNA-templated","prothymosin alpha pseudogene 9","[PTMA_BOVIN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_HUMAN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_MOUSE|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_PONAB|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_RAT|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;"]
[100506514,"'LOC100506514'",0,1,7,2.66666666666667,{"$nulls":4},"GO:0005622///intracellular","GO:0005525///GTP binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity","GO:0006164///purine nucleotide biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process","uncharacterized LOC100506514","[ZKSC2_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 2; AltName: Full=Zinc finger protein 694;+++[ZSC20_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31; AltName: Full=Zinc finger protein 360; AltName: Full=Zinc finger protein KOX29;+++[ZSC20_MOUSE|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31;+++[ZSC29_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 29; AltName: Full=Zinc finger protein 690;"]
[100506564,"'THEGL'",15,12,11,12.6666666666667,{"$nulls":7},"theg spermatid protein like","[THEGL_HUMAN|Reviewed]RecName: Full=Testicular haploid expressed gene protein-like; AltName: Full=Theg spermatid-like protein;"]
[100506581,"'C16orf95'",27,27,43,32.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"chromosome 16 open reading frame 95","[CP095_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C16orf95;+++[A0A087X224_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000484646};+++[H3BNZ7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000455079};"]
[100506658,"'OCLN'",109,106,125,113.333333333333,"04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++05160///Hepatitis C","H00840///Band-like calcification with simplified gyration and polymicrogyria (BLC-PMG)",null,null,"GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005911///cell-cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0005923///bicellular tight junction+++GO:0016327///apicolateral plasma membrane+++GO:0030139///endocytic vesicle+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0070673///response to interleukin-18+++GO:0045216///cell-cell junction organization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0065003///protein-containing complex assembly+++GO:2000810///regulation of bicellular tight junction assembly+++GO:0070830///bicellular tight junction assembly","occludin","[OCLN_HUMAN|Reviewed]RecName: Full=Occludin;+++[A0A0G2JMZ8_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};+++[A0A0G2JPF2_HUMAN|Unreviewed]SubName: Full=Occludin {ECO:0000313|Ensembl:ENSP00000483480};+++[A8K3T2_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};"]
[100507050,"'TPBGL'",2,3,1,2,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"trophoblast glycoprotein like","[TPBGL_HUMAN|Reviewed]RecName: Full=Trophoblast glycoprotein-like; Flags: Precursor;"]
[100507055,"'LRCOL1'",3,8,9,6.66666666666667,{"$nulls":4},"GO:0005576///extracellular region","GO:0008047///enzyme activator activity","GO:0043085///positive regulation of catalytic activity+++GO:0007586///digestion+++GO:0032094///response to food+++GO:0016042///lipid catabolic process","leucine rich colipase like 1","[LRCL1_HUMAN|Reviewed]RecName: Full=Leucine-rich colipase-like protein 1; Flags: Precursor;+++[A0A087WT69_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000477635};+++[A0A087WYD7_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000481713};+++[A0A087WZ94_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000482471};"]
[100507290,"'ZNF865'",1066,1153,1178,1132.33333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","zinc finger protein 865","[ZN865_HUMAN|Reviewed]RecName: Full=Zinc finger protein 865;+++[A0A0D9SG26_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 865 {ECO:0000313|Ensembl:ENSP00000487098};"]
[100507421,"'TMEM178B'",358,489,349,398.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","transmembrane protein 178B","[T178B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 178B; Flags: Precursor;+++[A0A087X1B3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 178B {ECO:0000313|Ensembl:ENSP00000484025};"]
[100507436,"'MICA'",1974,2717,2472,2387.66666666667,"05167///Kaposi's sarcoma-associated herpesvirus infection","H00288///Familial Mediterranean fever (FMF)",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0030881///beta-2-microglobulin binding","GO:0050776///regulation of immune response+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0051607///defense response to virus+++GO:0009408///response to heat+++GO:0046629///gamma-delta T cell activation+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0030101///natural killer cell activation+++GO:0019835///cytolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0032815///negative regulation of natural killer cell activation+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042742///defense response to bacterium+++GO:0016032///viral process+++GO:0002418///immune response to tumor cell+++GO:0001913///T cell mediated cytotoxicity","MHC class I polypeptide-related sequence A",{"$cut":{"chars":22248,"head":"[MICA_HUMAN|Reviewed]RecName: Full=MHC class I polypeptide-related sequence A; Short=MIC-A; Flags: Precursor;+++[A0A023SER7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74089.1}; Flags: Fragment;+++[A0A023SGA8_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74088.1}; Flags: Fragment;+++[A0A024RCL3_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A, isoform CRA_a {ECO:0000313|EMBL:EAX03394.1};+++[A0A0F6UUZ2_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I chain-related protein A {ECO:0000313|EMBL:AKE78870.1}; Flags: Fragment;+++[A0A0G2JJ55_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000405177};+++[A0A0G2JK11_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000412992};+++[A0A0K1NWU9_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75046.1}; Flags: Fragment;+++[A0A0K1NXC7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75047.1}; Flags: Fragment;+++[A0A0K1NXW1_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75045.1}; Flags: Fragment;+++[A0A0M3LAT3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11906.1}; Flags: Fragment;+++[A0A0M3LAU3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11916.1}; Flags: Fragment;+++[A0A0M3LAV0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11908.1}; Flags: Fragment;+++[A0A0M3LAV5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11926.1}; Flags: Fragment;+++[A0A0M3LAW0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11918.1}; Flags: Fragment;+++[A0A0M3LAW3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11936.1}; Flags: Fragment;+++[A0A0M3LAW8_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11928.1}; Flags: Fragment;+++[A0A0M3LAX6_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11938.1}; Flags: Fragment;+++[A0A0M3LAX7_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11946.1}; Flags: Fragment;+++[A0A0M3LAY5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11948.1}; Flags: Fragment;+++[A0A0M3LB05_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11905.1}; Flags: Fragment;+++[A0A0M3LB16_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11903.1}; Flags: Fragment;+++[A0A0M3LB17_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11915.1}; Flags: Fragment;+++[A0A0M3LB24_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11913.1}; Flags: Fragment;+++[A0A0M3LB25_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11925.1}; Flags: Fragment;+++[A0A0M3LB32_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11923.1}; Flags: Fragment;+++[A0A0M3LB33_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11935.1}; Flags: Fragment;+++[A0A0M3LB39_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11945.1}; Flags: Fragment;+++[A0A0M3LB40_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11933.1}; Flags: Fragment;+++[A0A0M3LB48_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11955.1}; Flags: Fragment;+++[A0A0M3LB49_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11943.1}; Flags: Fragment;+++[A0A0M3LB59_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11953.1}; Flags: Fragment;+++[A0A0M3LB64_HUMAN|Unreviewed]SubName: Ful"}}]
[100507462,"'GVQW2'",3,1,0,1.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","GVQW motif containing 2","[GVQW2_HUMAN|Reviewed]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};"]
[100507507,"'LOC100507507'",111,153,173,145.666666666667,{"$nulls":7},"uncharacterized LOC100507507","[A0A2J8V2S2_PONAB|diamond]SubName: Full=T0078241 isoform 1 {ECO:0000313|EMBL:PNJ51828.1};"]
[100507537,"'DWORF'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008047///enzyme activator activity","GO:1902082///positive regulation of calcium ion import into sarcoplasmic reticulum+++GO:0031449///regulation of slow-twitch skeletal muscle fiber contraction+++GO:1901894///regulation of calcium-transporting ATPase activity","DWARF open reading frame","[A0A1B0GTW0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000489859};"]
[100507588,"'TGFBR3L'",47,58,70,58.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transforming growth factor beta receptor 3 like","[TGR3L_HUMAN|Reviewed]RecName: Full=Transforming growth factor-beta receptor type 3-like protein; AltName: Full=TGF-beta receptor type-3-like protein; Short=TGFR-3L; AltName: Full=Transforming growth factor-beta receptor type III-like protein; Short=TGF-beta receptor type III-like protein;"]
[100507607,"'NPIPB9'",16.43,29.46,7.93,17.94,"01100///Metabolic pathways+++00650///Butanoate metabolism",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm",null,null,"nuclear pore complex interacting protein family member B9","[NPIB9_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B9;+++[F8VUA1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B9 {ECO:0000313|Ensembl:ENSP00000350444};"]
[100507747,"'C13orf46'",81,66,57,68,{"$nulls":7},"chromosome 13 open reading frame 46","[CM046_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C13orf46 {ECO:0000305};"]
[100509620,"'LOC100509620'",1,0,0,0.333333333333333,"04923///Regulation of lipolysis in adipocytes+++03320///PPAR signaling pathway","H02106///Genetic obesity",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015267///channel activity","GO:0055085///transmembrane transport","putative aquaporin-7-like protein 3","[A0A075B734_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000456868};"]
[10051,"'SMC4'",165,146,146,152.333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005694///chromosome","GO:0003697///single-stranded DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0030261///chromosome condensation+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0051383///kinetochore organization+++GO:0045132///meiotic chromosome segregation+++GO:0000070///mitotic sister chromatid segregation+++GO:0010032///meiotic chromosome condensation+++GO:0051276///chromosome organization+++GO:0051301///cell division","structural maintenance of chromosomes 4","[SMC4_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 4; Short=SMC protein 4; Short=SMC-4; AltName: Full=Chromosome-associated polypeptide C; Short=hCAP-C; AltName: Full=XCAP-C homolog;+++[B3KXX5_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[C9IYK2_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418820}; Flags: Fragment;+++[C9J578_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417999}; Flags: Fragment;+++[C9J9E4_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417612}; Flags: Fragment;+++[C9JJ64_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420817}; Flags: Fragment;+++[C9JR83_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420121}; Flags: Fragment;+++[C9JVD8_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419360}; Flags: Fragment;+++[C9JWF0_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419247}; Flags: Fragment;+++[E9PD53_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[F8WCB7_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418434};+++[Q58F29_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH01557.1}; Flags: Fragment;+++[Q6NSG3_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH70161.1}; Flags: Fragment;+++[Q6P169_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH65259.1}; Flags: Fragment;"]
[10052,"'GJC1'",255,196.01,173.23,208.08,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0014704///intercalated disc+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016021///integral component of membrane+++GO:0005922///connexin complex","GO:0086077///gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling+++GO:0005216///ion channel activity+++GO:0086020///gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling","GO:0086014///atrial cardiac muscle cell action potential+++GO:0086021///SA node cell to atrial cardiac muscle cell communication by electrical coupling+++GO:0048738///cardiac muscle tissue development+++GO:0048468///cell development+++GO:0007043///cell-cell junction assembly+++GO:0086053///AV node cell to bundle of His cell communication by electrical coupling+++GO:0006936///muscle contraction+++GO:0007268///chemical synaptic transmission+++GO:0016264///gap junction assembly+++GO:0007601///visual perception+++GO:0001570///vasculogenesis","gap junction protein gamma 1","[CXG1_HUMAN|Reviewed]RecName: Full=Gap junction gamma-1 protein; AltName: Full=Connexin-45; Short=Cx45; AltName: Full=Gap junction alpha-7 protein;"]
[100526664,"'LY75-CD302'",3.36,0,0,1.12,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0043130///ubiquitin binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0038023///signaling receptor activity+++GO:0008270///zinc ion binding","GO:0006955///immune response+++GO:0008284///positive regulation of cell proliferation+++GO:0042130///negative regulation of T cell proliferation+++GO:1901799///negative regulation of proteasomal protein catabolic process+++GO:0006954///inflammatory response+++GO:0051865///protein autoubiquitination+++GO:0006897///endocytosis+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0050821///protein stabilization+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0002643///regulation of tolerance induction+++GO:1905524///negative regulation of protein autoubiquitination","LY75-CD302 readthrough","[LY75_HUMAN|Reviewed]RecName: Full=Lymphocyte antigen 75; Short=Ly-75; AltName: Full=C-type lectin domain family 13 member B; AltName: Full=DEC-205; AltName: Full=gp200-MR6; AltName: CD_antigen=CD205; Flags: Precursor;"]
[100526693,"'ARPC4-TTLL3'",229.57,239.58,259.69,242.946666666667,{"$nulls":4},"GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton","GO:0003779///actin binding+++GO:0070735///protein-glycine ligase activity","GO:0018094///protein polyglycylation+++GO:0006464///cellular protein modification process+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030041///actin filament polymerization+++GO:0030833///regulation of actin filament polymerization","ARPC4-TTLL3 readthrough","[A0A0A6YYG9_HUMAN|Unreviewed]SubName: Full=Protein ARPC4-TTLL3 {ECO:0000313|Ensembl:ENSP00000380427};+++[F8WCF6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000256|PIRNR:PIRNR039100};+++[F8WE39_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000402163};+++[H7C0A3_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000393764}; Flags: Fragment;"]
[100526694,"'MSANTD3-TMEFF1'",72.45,91.91,115.85,93.4033333333334,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding","GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007517///muscle organ development","MSANTD3-TMEFF1 readthrough","[TEFF1_HUMAN|Reviewed]RecName: Full=Tomoregulin-1; Short=TR-1; AltName: Full=H7365; AltName: Full=Transmembrane protein with EGF-like and one follistatin-like domain; Flags: Precursor;+++[A0A0A6YYJ0_HUMAN|Unreviewed]SubName: Full=Protein MSANTD3-TMEFF1 {ECO:0000313|Ensembl:ENSP00000424768};"]
[100526737,"'RBM14-RBM4'",14.44,9.39,25.65,16.4933333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0098534///centriole assembly+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0002190///cap-independent translational initiation+++GO:0008380///RNA splicing+++GO:0045087///innate immune response+++GO:0030154///cell differentiation+++GO:0032055///negative regulation of translation in response to stress+++GO:0017148///negative regulation of translation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002192///IRES-dependent translational initiation of linear mRNA+++GO:0045947///negative regulation of translational initiation+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0046685///response to arsenic-containing substance+++GO:0097167///circadian regulation of translation+++GO:0006397///mRNA processing+++GO:0035278///miRNA mediated inhibition of translation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0046822///regulation of nucleocytoplasmic transport","RBM14-RBM4 readthrough","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0A0MSL8_HUMAN|Unreviewed]SubName: Full=RBM14-RBM4 readthrough {ECO:0000313|Ensembl:ENSP00000395880};+++[A0A0A6YYI9_HUMAN|Unreviewed]SubName: Full=Protein RBM14-RBM4 {ECO:0000313|Ensembl:ENSP00000421279};"]
[100526739,"'CENPS-CORT'",72.55,56.79,67.34,65.56,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0071821///FANCM-MHF complex+++GO:0005576///extracellular region","GO:0046982///protein heterodimerization activity+++GO:0005179///hormone activity","GO:0010469///regulation of signaling receptor activity","CENPS-CORT readthrough","[CENPS_HUMAN|Reviewed]RecName: Full=Centromere protein S; Short=CENP-S; AltName: Full=Apoptosis-inducing TAF9-like domain-containing protein 1; AltName: Full=FANCM-associated histone fold protein 1 {ECO:0000303|PubMed:20347428}; AltName: Full=FANCM-interacting histone fold protein 1 {ECO:0000303|PubMed:20347429}; AltName: Full=Fanconi anemia-associated polypeptide of 16 kDa;+++[A0A087WT10_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000473401};+++[A0A0U1RQL5_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000489060}; SubName: Full=Centromere protein S {ECO:0000313|Ensembl:ENSP00000489524};"]
[100526740,"'ATP5MF-PTCD1'",31.86,21.87,28.37,27.3666666666667,{"$nulls":4},"GO:0005759///mitochondrial matrix","GO:0000049///tRNA binding","GO:0042780///tRNA 3'-end processing","ATP5MF-PTCD1 readthrough","[B4DJ38_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56092, highly similar to Pentatricopeptide repeat protein 1 {ECO:0000313|EMBL:BAG58700.1};+++[C9JJT5_HUMAN|Unreviewed]SubName: Full=ATP5MF-PTCD1 readthrough {ECO:0000313|Ensembl:ENSP00000416954};+++[G3V325_HUMAN|Unreviewed]SubName: Full=ATP5MF-PTCD1 readthrough {ECO:0000313|Ensembl:ENSP00000400168};"]
[100526760,"'ABHD14A-ACY1'",0,23.16,51.39,24.85,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01230///Biosynthesis of amino acids+++00220///Arginine biosynthesis+++01210///2-Oxocarboxylic acid metabolism+++01130///Biosynthesis of antibiotics","H01146///Aminoacylase 1 deficiency","M00028///Ornithine biosynthesis, glutamate => ornithine","R00669///N2-Acetyl-L-ornithine amidohydrolase   N-Acetylornithine + H2O <=> Acetate + L-Ornithine+++R10553///N-acetyl-L-cysteine-S-conjugate amidohydrolase (carboxylate-forming)   S-Substituted N-acetyl-L-cysteine + H2O <=> S-Substituted L-cysteine + Acetate","GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0004046///aminoacylase activity+++GO:0008237///metallopeptidase activity","GO:0006520///cellular amino acid metabolic process+++GO:0006508///proteolysis","ABHD14A-ACY1 readthrough","[A0A1B0GU64_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000489981};+++[A0A1B0GUT4_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490236};+++[A0A1B0GV31_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490353}; Flags: Fragment;+++[A0A1B0GVA5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490434}; Flags: Fragment;+++[A0A1B0GVC5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490460}; Flags: Fragment;+++[A0A1B0GVN8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490593}; Flags: Fragment;+++[A0A1B0GVQ8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490616}; Flags: Fragment;+++[A0A1B0GVW5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490680}; Flags: Fragment;+++[A0A1B0GW23_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490744}; Flags: Fragment;+++[A0A1B0GW28_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490750}; Flags: Fragment;+++[A0A1B0GWD9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490887};+++[B4DNW0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60317, highly similar to Aminoacylase-1 {ECO:0000313|EMBL:BAG60372.1};+++[C9JMV9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420487};+++[F2Z3Q0_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420395};"]
[100526761,"'CCDC169-SOHLH2'",0,9,0,3,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity","GO:0007283///spermatogenesis+++GO:0006366///transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0009994///oocyte differentiation","CCDC169-SOHLH2 readthrough","[SOLH2_HUMAN|Reviewed]RecName: Full=Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2;"]
[100526767,"'RNF103-CHMP3'",0,7.83,10.14,5.99,"04217///Necroptosis+++04144///Endocytosis",null,"M00412///ESCRT-III complex",null,"GO:0031410///cytoplasmic vesicle+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0000815///ESCRT III complex+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016021///integral component of membrane+++GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005770///late endosome+++GO:0010494///cytoplasmic stress granule+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0031902///late endosome membrane","GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0031210///phosphatidylcholine binding+++GO:0050681///androgen receptor binding+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0003727///single-stranded RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:1990381///ubiquitin-specific protease binding+++GO:0003697///single-stranded DNA binding+++GO:0051213///dioxygenase activity+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0031490///chromatin DNA binding+++GO:0032452///histone demethylase activity","GO:0007034///vacuolar transport","RNF103-CHMP3 readthrough","[CHMP3_HUMAN|Reviewed]RecName: Full=Charged multivesicular body protein 3; AltName: Full=Chromatin-modifying protein 3; AltName: Full=Neuroendocrine differentiation factor; AltName: Full=Vacuolar protein sorting-associated protein 24; Short=hVps24;+++[A0A140T963_HUMAN|Unreviewed]SubName: Full=RNF103-CHMP3 readthrough {ECO:0000313|Ensembl:ENSP00000392995}; Flags: Fragment;"]
[100526772,"'TMEM110-MUSTN1'",0,13.86,7.26,7.04,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005246///calcium channel regulator activity","GO:0042246///tissue regeneration+++GO:0035988///chondrocyte proliferation+++GO:0002062///chondrocyte differentiation","TMEM110-MUSTN1 readthrough","[A8MSY1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422941};+++[H0Y8V1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422189}; Flags: Fragment;"]
[100526783,"'C15orf38-AP3S2'",620.39,735.63,516.98,624.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030117///membrane coat+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051126///negative regulation of actin nucleation","C15orf38-AP3S2 readthrough","[A0A0A6YYH1_HUMAN|Unreviewed]SubName: Full=Protein C15orf38-AP3S2 {ECO:0000313|Ensembl:ENSP00000381377};+++[H0YL85_HUMAN|Unreviewed]SubName: Full=C15orf38-AP3S2 readthrough {ECO:0000313|Ensembl:ENSP00000453100}; Flags: Fragment;+++[H0YMK0_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588}; Flags: Fragment;"]
[100526794,"'NT5C1B-RDH14'",1.68,0,0,0.56,"00240///Pyrimidine metabolism+++00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites","H00674///Anemia due to disorders of nucleotide metabolism",null,"R02102///2'-deoxyuridine 5'-monophosphate phosphohydrolase   dUMP + H2O <=> Deoxyuridine + Orthophosphate+++R00963///uridine 5'-monophosphate phosphohydrolase   UMP + H2O <=> Uridine + Orthophosphate+++R00183///adenosine 5'-monophosphate phosphohydrolase   AMP + H2O <=> Adenosine + Orthophosphate+++R02088///2'-deoxyadenosine 5'-monophosphate phosphohydrolase   dAMP + H2O <=> Deoxyadenosine + Orthophosphate+++R01664///2'-deoxycytidine 5'-monophosphate phosphohydrolase   dCMP + H2O <=> Deoxycytidine + Orthophosphate+++R01126///inosine 5'-monophosphate phosphohydrolase   IMP + H2O <=> Inosine + Orthophosphate+++R02323///nicotinamide ribonucleotide phosphohydrolase   Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate+++R01227///guanosine 5'-monophosphate phosphohydrolase   GMP + H2O <=> Guanosine + Orthophosphate+++R02719///xanthosine 5'-phosphate phosphohydrolase   Xanthosine 5'-phosphate + H2O <=> Xanthosine + Orthophosphate+++R00511///cytidine-5'-monophosphate phosphohydrolase   CMP + H2O <=> Cytidine + Orthophosphate+++R01968///2'-deoxyguanosine 5'-monophosphate phosphohydrolase   dGMP + H2O <=> Deoxyguanosine + Orthophosphate+++R01569///thymidylate 5'-phosphohydrolase   dTMP + H2O <=> Thymidine + Orthophosphate+++R03346///nicotinate D-ribonucleotide phosphohydrolase   Nicotinate D-ribonucleotide + H2O <=> Nicotinate D-ribonucleoside + Orthophosphate","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0008253///5'-nucleotidase activity+++GO:0000287///magnesium ion binding","GO:0009117///nucleotide metabolic process+++GO:0016311///dephosphorylation","NT5C1B-RDH14 readthrough","[5NT1B_HUMAN|Reviewed]RecName: Full=Cytosolic 5'-nucleotidase 1B; Short=cN1B; EC=3.1.3.5; AltName: Full=Autoimmune infertility-related protein; AltName: Full=Cytosolic 5'-nucleotidase IB; Short=cN-IB;+++[C9J2C7_HUMAN|Unreviewed]SubName: Full=NT5C1B-RDH14 readthrough {ECO:0000313|Ensembl:ENSP00000412639}; Flags: Fragment;"]
[100526835,"'FPGT-TNNI3K'",8.63,11.63,12.46,10.9066666666667,"00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H02125///Cardiac conduction disease with dilated cardiomyopathy",null,"R01951///GTP:beta-L-fucose-1-phosphate guanylyltransferase GTP + L-Fucose 1-phosphate <=> Diphosphate + GDP-L-fucose","GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade","FPGT-TNNI3K readthrough","[TNI3K_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase TNNI3K; EC=2.7.11.1; AltName: Full=Cardiac ankyrin repeat kinase; AltName: Full=Cardiac troponin I-interacting kinase; AltName: Full=TNNI3-interacting kinase;+++[A6NHC7_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000359930};+++[E9PKE1_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000433587}; Flags: Fragment;+++[V9GXZ4_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000450895};"]
[100526842,"'RPL17-C18orf32'",53.58,28.08,57.17,46.2766666666667,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0002181///cytoplasmic translation","RPL17-C18orf32 readthrough","[A0A0A0MRF8_HUMAN|Unreviewed]SubName: Full=RPL17-C18orf32 readthrough {ECO:0000313|Ensembl:ENSP00000352143};+++[A0A0A6YYL6_HUMAN|Unreviewed]SubName: Full=Protein RPL17-C18orf32 {ECO:0000313|Ensembl:ENSP00000463379};"]
[100527943,"'TGIF2-RAB5IF'",12.97,0,16.9,9.95666666666667,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","TGIF2-RAB5IF readthrough","[A0A0A6YYL0_HUMAN|Unreviewed]SubName: Full=Protein TGIF2-C20orf24 {ECO:0000313|Ensembl:ENSP00000454021};"]
[100527963,"'PMF1-BGLAP'",76.56,94.78,82.29,84.5433333333333,"04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0000818///nuclear MIS12/MIND complex+++GO:0005829///cytosol+++GO:0005667///transcription factor complex+++GO:0000444///MIS12/MIND type complex+++GO:0005794///Golgi apparatus+++GO:0005694///chromosome+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region","GO:0043522///leucine zipper domain binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding","GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006366///transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation","PMF1-BGLAP readthrough","[PMF1_HUMAN|Reviewed]RecName: Full=Polyamine-modulated factor 1; Short=PMF-1;+++[A0A087WT04_HUMAN|Unreviewed]SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000458021};+++[U3KQ54_HUMAN|Unreviewed]SubName: Full=HCG2044777 {ECO:0000313|EMBL:EAW52985.1}; SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000475561};+++[V9GYH6_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476760}; Flags: Fragment;+++[V9GYI0_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476770};"]
[100527978,"'TMEM56-RWDD3'",12.78,2.08,2.33,5.73,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0033235///positive regulation of protein sumoylation+++GO:1902073///positive regulation of hypoxia-inducible factor-1alpha signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","TMEM56-RWDD3 readthrough","[S4R3V7_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000474793}; Flags: Fragment;+++[S4R434_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000475025};"]
[100528020,"'FAM187A'",31,15,31,25.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"family with sequence similarity 187 member A","[F187A_HUMAN|Reviewed]RecName: Full=Ig-like V-type domain-containing protein FAM187A; Flags: Precursor;"]
[100528030,"'POC1B-GALNT4'",0,7.51,2.5,3.33666666666667,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0006486///protein glycosylation","POC1B-GALNT4 readthrough","[GALT4_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 4; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 4; Short=GalNAc-T4; Short=pp-GaNTase 4; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 4; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4;+++[F8VUJ3_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[F8VZB3_HUMAN|Unreviewed]SubName: Full=POC1B-GALNT4 readthrough {ECO:0000313|Ensembl:ENSP00000447754};"]
[100528062,"'ARMCX5-GPRASP2'",60.23,31.2,130.17,73.8666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0003697///single-stranded DNA binding+++GO:0001540///amyloid-beta binding+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity","GO:0050769///positive regulation of neurogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:1990172///G protein-coupled receptor catabolic process+++GO:0007611///learning or memory+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0006351///transcription, DNA-templated+++GO:0032197///transposition, RNA-mediated+++GO:0008333///endosome to lysosome transport+++GO:0051965///positive regulation of synapse assembly","ARMCX5-GPRASP2 readthrough","[GASP2_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 2; Short=GASP-2;"]
[100528064,"'NEDD8-MDP1'",7.01,0,14.31,7.10666666666667,"04144///Endocytosis+++04217///Necroptosis","H01202///Cataract","M00412///ESCRT-III complex",null,"GO:0030659///cytoplasmic vesicle membrane+++GO:0031902///late endosome membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0000815///ESCRT III complex+++GO:0030496///midbody+++GO:0030117///membrane coat+++GO:0005737///cytoplasm","GO:0016791///phosphatase activity","GO:0016311///dephosphorylation","NEDD8-MDP1 readthrough","[E9PL57_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000431482}; Flags: Fragment;+++[E9PS38_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000432117};+++[S4R3E9_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000474249};"]
[100529063,"'BCL2L2-PABPN1'",70.54,34.3,80.19,61.6766666666667,"03015///mRNA surveillance pathway+++05164///Influenza A","H00704///Oculopharyngeal muscular dystrophy (OPMD)",null,null,"GO:0005774///vacuolar membrane+++GO:0042405///nuclear inclusion body+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0031301///integral component of organelle membrane+++GO:0016607///nuclear speck+++GO:0005887///integral component of plasma membrane+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex","GO:0097718///disordered domain specific binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0070063///RNA polymerase binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043621///protein self-association+++GO:0051400///BH domain binding+++GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity","GO:0031124///mRNA 3'-end processing+++GO:0015891///siderophore transport+++GO:0060011///Sertoli cell proliferation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0006396///RNA processing+++GO:1904247///positive regulation of polynucleotide adenylyltransferase activity+++GO:0007283///spermatogenesis+++GO:0055072///iron ion homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006936///muscle contraction+++GO:0006397///mRNA processing+++GO:0006369///termination of RNA polymerase II transcription+++GO:0000165///MAPK cascade+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0046778///modification by virus of host mRNA processing+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage","BCL2L2-PABPN1 readthrough","[AR1_XENLA|diamond]RecName: Full=Apoptosis regulator R1; AltName: Full=XR1; Flags: Fragment;+++[B2CL2_BOVIN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_CANLF|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_HUMAN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_MOUSE|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W; AltName: Full=c98;+++[PAB2A_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-A; Short=PABP-2-A; Short=Poly(A)-binding protein 2-A; AltName: Full=Nuclear poly(A)-binding protein 1-A; AltName: Full=Poly(A)-binding protein II-A; Short=PABII-A; AltName: Full=Polyadenylate-binding nuclear protein 1-A; AltName: Full=XLnPABP2-A; AltName: Full=nPABP2-A; AltName: Full=xPABPII-A;+++[PAB2B_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-B; Short=PABP-2-B; Short=Poly(A)-binding protein 2-B; AltName: Full=Nuclear poly(A)-binding protein 1-B; AltName: Full=Poly(A)-binding protein II-B; Short=PABII-B; AltName: Full=Polyadenylate-binding nuclear protein 1-B; AltName: Full=XLnPABP2-B; AltName: Full=nPABP2-B; AltName: Full=xPABPII-B;+++[PABP2_BOVIN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_HUMAN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_MOUSE|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_XENTR|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[S22AH_BOVIN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Lipocalin-2 receptor;+++[S22AH_HUMAN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor; AltName: Full=Neutrophil gelatinase-associated lipocalin receptor; Short=NgalR;+++[S22AH_MOUSE|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AH_RAT|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AV_HUMAN|diamond]RecName: Full=Putative solute carrier family 22 member 31 {ECO:0000305};"]
[100529097,"'RPL36A-HNRNPH2'",740.47,845.23,793.55,793.083333333333,"03010///Ribosome","H00658///Syndromic X-linked mental retardation+++H00125///Fabry disease","M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes","R01329///Epimelibiose galactohydrolase Epimelibiose + H2O <=> D-Mannose + D-Galactose+++R03634///Stachyose + H2O <=> Raffinose + D-Galactose+++R05961///H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide+++R01194///3-O-alpha-D-Galactosyl-1D-myo-inositol galactohydrolase; 1-alpha-D-Galactosyl-myo-inositol alpha-D-Galactosyl-(1->3)-1D-myo-inositol + H2O <=> myo-Inositol + D-Galactose+++R04019///Digalactosylceramide galactohydrolase Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose+++R04470///Digalactosyl-diacylglycerol galactohydrolase Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose+++R05549///D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose+++R06091///Melibiose + H2O <=> D-Galactose + D-Glucose+++R01104///Galactosylglycerol galactohydrolase 3-beta-D-Galactosyl-sn-glycerol + H2O <=> D-Galactose + Glycerol+++R01101///melibiose galactohydrolase Melibiose + H2O <=> D-Galactose + D-Glucose+++R02926///Melibiitol galactohydrolase Melibiitol + H2O <=> D-Sorbitol + D-Galactose+++R01103///Raffinose galactohydrolase Raffinose + H2O <=> D-Galactose + Sucrose","GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005783///endoplasmic reticulum","GO:0003735///structural constituent of ribosome","GO:0006412///translation","RPL36A-HNRNPH2 readthrough","[H0Y3V9_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386974};+++[H7BZ11_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386655};"]
[100529144,"'CORO7-PAM16'",59.13,199.35,22.28,93.5866666666667,null,"H01830///Spondylometaphyseal dysplasia, Megarbane-Dagher-Melki type (SMDMDM)",null,null,"GO:0005794///Golgi apparatus","GO:0003779///actin binding","GO:0001503///ossification+++GO:0030150///protein import into mitochondrial matrix+++GO:0032780///negative regulation of ATPase activity+++GO:0030041///actin filament polymerization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","CORO7-PAM16 readthrough","[A0A0A6YYL4_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};+++[I3L167_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};"]
[100529215,"'ZNF559-ZNF177'",3.23,0,6.92,3.38333333333333,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","ZNF559-ZNF177 readthrough","[ZN177_HUMAN|Reviewed]RecName: Full=Zinc finger protein 177;+++[S4R342_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473911};+++[S4R365_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473968};+++[S4R367_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473974}; Flags: Fragment;+++[S4R3A1_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474076};+++[S4R3B1_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474108}; Flags: Fragment;+++[S4R3H7_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474354};+++[S4R3Q2_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474602}; Flags: Fragment;+++[S4R3T9_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474716}; Flags: Fragment;+++[S4R401_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474918}; Flags: Fragment;+++[S4R422_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474980};"]
[100529240,"'ZNF816-ZNF321P'",10.21,10.72,9.17,10.0333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","ZNF816-ZNF321P readthrough","[ZN321_HUMAN|Reviewed]RecName: Full=Putative protein ZNF321; AltName: Full=Zinc finger protein 321 pseudogene;+++[A0A0X1KG74_HUMAN|Unreviewed]SubName: Full=ZNF816-ZNF321P readthrough {ECO:0000313|Ensembl:ENSP00000375656};"]
[100529251,"'CKLF-CMTM1'",4.3,1.21,0,1.83666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005125///cytokine activity","GO:0006935///chemotaxis","CKLF-CMTM1 readthrough","[A0A087WVB3_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000479319};+++[A0A087X286_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000484781};+++[E9PIV8_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433857};+++[E9PLU7_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000435007}; SubName: Full=Chemokine-like factor {ECO:0000313|Ensembl:ENSP00000431270};+++[E9PSG2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433998};+++[H0YDF2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433503}; Flags: Fragment;"]
[100529257,"'SYNJ2BP-COX16'",0,4.18,0,1.39333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016323///basolateral plasma membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0031966///mitochondrial membrane+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0098839///postsynaptic density membrane+++GO:0031594///neuromuscular junction","GO:0035255///ionotropic glutamate receptor binding","GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0043113///receptor clustering+++GO:0098609///cell-cell adhesion+++GO:0097120///receptor localization to synapse+++GO:0007268///chemical synaptic transmission","SYNJ2BP-COX16 readthrough","[A0A087WTA2_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000477705};+++[A0A087WUM0_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000478757}; Flags: Fragment;+++[A0A087WX56_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000480746}; Flags: Fragment;+++[A0A087WYV9_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000482133};+++[A0A087X1F5_HUMAN|Unreviewed]SubName: Full=SYNJ2BP-COX16 readthrough {ECO:0000313|Ensembl:ENSP00000484161}; Flags: Fragment;"]
[100529261,"'CHURC1-FNTB'",0,88.76,8.78,32.5133333333333,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis",null,null,"R09844///farnesyl-diphosphate:protein-cysteine farnesyltransferase trans,trans-Farnesyl diphosphate + Protein-cysteine <=> S-Farnesyl protein + Diphosphate","GO:0005965///protein farnesyltransferase complex","GO:0004659///prenyltransferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004660///protein farnesyltransferase activity+++GO:0003824///catalytic activity+++GO:0008270///zinc ion binding","GO:0007275///multicellular organism development+++GO:0018343///protein farnesylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0018342///protein prenylation","CHURC1-FNTB readthrough","[FNTB_HUMAN|Reviewed]RecName: Full=Protein farnesyltransferase subunit beta; Short=FTase-beta; EC=2.5.1.58; AltName: Full=CAAX farnesyltransferase subunit beta; AltName: Full=Ras proteins prenyltransferase subunit beta;+++[B4DL54_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000447121}; SubName: Full=cDNA FLJ59570, highly similar to Protein farnesyltransferase subunit beta {ECO:0000313|EMBL:BAG59416.1};+++[H0YIM3_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000449668}; Flags: Fragment;+++[H0YIM9_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000449709}; Flags: Fragment;+++[H0YJ25_HUMAN|Unreviewed]SubName: Full=CHURC1-FNTB readthrough {ECO:0000313|Ensembl:ENSP00000450692}; Flags: Fragment;"]
[10053,"'AP1M2'",23,27,30,26.6666666666667,"04142///Lysosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000139///Golgi membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0030131///clathrin adaptor complex+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006605///protein targeting+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0050690///regulation of defense response to virus by virus+++GO:0006886///intracellular protein transport+++GO:0006903///vesicle targeting+++GO:0015031///protein transport","adaptor related protein complex 1 subunit mu 2","[AP1M2_HUMAN|Reviewed]RecName: Full=AP-1 complex subunit mu-2; AltName: Full=AP-mu chain family member mu1B; AltName: Full=Adaptor protein complex AP-1 subunit mu-2; AltName: Full=Adaptor-related protein complex 1 subunit mu-2; AltName: Full=Clathrin assembly protein complex 1 mu-2 medium chain 2; AltName: Full=Golgi adaptor HA1/AP1 adaptin mu-2 subunit; AltName: Full=Mu-adaptin 2; AltName: Full=Mu1B-adaptin;+++[K7EJJ1_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465193}; Flags: Fragment;+++[K7EK69_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465488}; Flags: Fragment;+++[K7EL08_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465865}; Flags: Fragment;+++[K7EMG5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000466494}; Flags: Fragment;+++[K7EPI9_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467406};+++[K7EPR4_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467498}; Flags: Fragment;+++[K7ERH5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000468260}; Flags: Fragment;+++[Q53GI5_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 1, mu 2 subunit variant {ECO:0000313|EMBL:BAD96666.1}; Flags: Fragment;"]
[100532726,"'NDUFC2-KCTD14'",200.57,100.28,152.87,151.24,"00190///Oxidative phosphorylation+++01100///Metabolic pathways+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04714///Thermogenesis+++05010///Alzheimer's disease+++05016///Huntington's disease+++04723///Retrograde endocannabinoid signaling","H00810///Progressive myoclonic epilepsy (PME/ EPM)","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0070469///respiratory chain+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0055114///oxidation-reduction process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone","NDUFC2-KCTD14 readthrough","[NDUCR_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2; AltName: Full=NDUFC2-KCTD14 readthrough transcript protein;+++[A0A087WUM3_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000478766};+++[A0A087WY27_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000481472};+++[E9PRQ4_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000435967};"]
[100532731,"'COMMD3-BMI1'",111.85,95.36,296.89,168.033333333333,"05206///MicroRNAs in cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer","H00025///Penile cancer",null,null,"GO:0016604///nuclear body+++GO:0035102///PRC1 complex+++GO:0005829///cytosol","GO:1990841///promoter-specific chromatin binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0006342///chromatin silencing+++GO:0006814///sodium ion transport","COMMD3-BMI1 readthrough","[BMI1_HUMAN|Reviewed]RecName: Full=Polycomb complex protein BMI-1; AltName: Full=Polycomb group RING finger protein 4; AltName: Full=RING finger protein 51;+++[Q5T8Z1_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000398759}; Flags: Fragment;+++[R4GMW6_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473382}; Flags: Fragment;+++[R4GMX3_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473391};+++[R4GN54_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473495}; Flags: Fragment;"]
[100533105,"'C8orf44-SGK3'",0,136.67,76.31,70.9933333333333,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0055037///recycling endosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0005737///cytoplasm+++GO:0005795///Golgi stack+++GO:0005654///nucleoplasm+++GO:0005769///early endosome","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0035091///phosphatidylinositol binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0016567///protein ubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0016320///endoplasmic reticulum membrane fusion+++GO:0090168///Golgi reassembly","C8orf44-SGK3 readthrough","[SGK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk3; EC=2.7.11.1; AltName: Full=Cytokine-independent survival kinase; AltName: Full=Serum/glucocorticoid-regulated kinase 3; AltName: Full=Serum/glucocorticoid-regulated kinase-like;+++[A0A024R807_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};"]
[100533106,"'ZHX1-C8orf76'",6.8,20.37,4.39,10.52,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","ZHX1-C8orf76 readthrough","[ZHX1R_HUMAN|Reviewed]RecName: Full=Zinc fingers and homeoboxes protein 1, isoform 2; AltName: Full=ZHX1-C8orf76 readthrough transcript protein;+++[A0A0X1KG80_HUMAN|Unreviewed]SubName: Full=Zinc fingers and homeoboxes protein 1, isoform 2 {ECO:0000313|Ensembl:ENSP00000481928}; Flags: Fragment;"]
[100533178,"'PRORY'",2,5,2,3,{"$nulls":7},"proline rich Y-linked","[PRORY_HUMAN|Reviewed]RecName: Full=Proline-rich protein, Y-linked;"]
[100533183,"'ZNF664-RFLNA'",80.5,83.34,82.27,82.0366666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061181///regulation of chondrocyte development+++GO:0061572///actin filament bundle organization","ZNF664-RFLNA readthrough","[RFLA_HUMAN|Reviewed]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;"]
[100533467,"'BIVM-ERCC5'",582.33,575.9,576.75,578.326666666667,"03420///Nucleotide excision repair","H00403///Disorders of nucleotide excision repair+++H01428///Xeroderma pigmentosum (XP)",null,null,"GO:0005634///nucleus","GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds","GO:0006281///DNA repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006295///nucleotide-excision repair, DNA incision, 3'-to lesion+++GO:0006289///nucleotide-excision repair","BIVM-ERCC5 readthrough","[A0A1W2PRR4_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492455}; Flags: Fragment;+++[A0A1W2PRU8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492444}; Flags: Fragment;+++[A0A1W2PS85_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492684};+++[Q59FZ7_HUMAN|Unreviewed]SubName: Full=DNA-repair protein complementing XP-G cells variant {ECO:0000313|EMBL:BAD92549.1}; Flags: Fragment;+++[R4GMW8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000491742}; SubName: Full=DNA repair protein-complementing XP-G cells {ECO:0000313|Ensembl:ENSP00000473384}; SubName: Full=ERCC5-202 protein {ECO:0000313|EMBL:CDY80175.1};"]
[100533496,"'TVP23C-CDRT4'",62.28,72.23,102.2,78.9033333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009306///protein secretion+++GO:0016192///vesicle-mediated transport","TVP23C-CDRT4 readthrough","[TV23C_HUMAN|Reviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog C;+++[A0A0A6YYB9_HUMAN|Unreviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};+++[E5RGC5_HUMAN|Unreviewed]SubName: Full=Golgi apparatus membrane protein TVP23 homolog C {ECO:0000313|Ensembl:ENSP00000428748}; SubName: Full=TVP23C-CDRT4 readthrough {ECO:0000313|Ensembl:ENSP00000430143};"]
[100533952,"'RBAK-RBAKDN'",1.2,2,3.52,2.24,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","RBAK-RBAKDN readthrough","[A0A0A6YYG8_HUMAN|Unreviewed]SubName: Full=Protein RBAK-RBAKDN {ECO:0000313|Ensembl:ENSP00000380112};+++[I3L0D1_HUMAN|Unreviewed]SubName: Full=HCG1647537, isoform CRA_b {ECO:0000313|EMBL:EAW87320.1}; SubName: Full=RBAK-RBAKDN readthrough {ECO:0000313|Ensembl:ENSP00000385560};"]
[100534012,"'TNFAIP8L2-SCNM1'",8.64,0,22.16,10.2666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0019899///enzyme binding+++GO:0046872///metal ion binding","GO:0042981///regulation of apoptotic process+++GO:0050868///negative regulation of T cell activation+++GO:0050728///negative regulation of inflammatory response+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045087///innate immune response","TNFAIP8L2-SCNM1 readthrough","[SCNM1_HUMAN|Reviewed]RecName: Full=Sodium channel modifier 1;"]
[100534592,"'URGCP-MRPS24'",0,0,2.35,0.783333333333333,{"$nulls":4},"GO:0005761///mitochondrial ribosome+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005743///mitochondrial inner membrane","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070125///mitochondrial translational elongation+++GO:0032543///mitochondrial translation+++GO:0070126///mitochondrial translational termination+++GO:0006412///translation","URGCP-MRPS24 readthrough","[S4R325_HUMAN|Unreviewed]SubName: Full=URGCP-MRPS24 readthrough {ECO:0000313|Ensembl:ENSP00000473871};"]
[100534599,"'ISY1-RAB43'",373.64,357.32,418.79,383.25,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000974///Prp19 complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex+++GO:0032588///trans-Golgi network membrane+++GO:0071012///catalytic step 1 spliceosome+++GO:0071020///post-spliceosomal complex+++GO:0030670///phagocytic vesicle membrane+++GO:0045335///phagocytic vesicle+++GO:0070062///extracellular exosome","GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005525///GTP binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003924///GTPase activity+++GO:0046872///metal ion binding","GO:0000350///generation of catalytic spliceosome for second transesterification step","ISY1-RAB43 readthrough","[ISY1_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ISY1 homolog;+++[H9XFA1_HUMAN|Unreviewed]SubName: Full=ISY1-RAB43 {ECO:0000313|EMBL:AFG72967.1}; Flags: Fragment;"]
[10054,"'UBA2'",604,672,532,602.666666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0031510///SUMO activating enzyme complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0005524///ATP binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0016881///acid-amino acid ligase activity+++GO:0000166///nucleotide binding+++GO:0008047///enzyme activator activity+++GO:0019948///SUMO activating enzyme activity+++GO:0000287///magnesium ion binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0044388///small protein activating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0044241///lipid digestion+++GO:0072148///epithelial cell fate commitment+++GO:0007411///axon guidance+++GO:0021800///cerebral cortex tangential migration+++GO:0030154///cell differentiation+++GO:0001764///neuron migration+++GO:0021846///cell proliferation in forebrain+++GO:0007275///multicellular organism development+++GO:0046622///positive regulation of organ growth+++GO:0043085///positive regulation of catalytic activity+++GO:0021772///olfactory bulb development+++GO:0030900///forebrain development+++GO:0010628///positive regulation of gene expression+++GO:0021759///globus pallidus development+++GO:0016925///protein sumoylation+++GO:0007399///nervous system development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0021831///embryonic olfactory bulb interneuron precursor migration+++GO:0006355///regulation of transcription, DNA-templated","ubiquitin like modifier activating enzyme 2","[SAE2_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 2; EC=2.3.2.-; AltName: Full=Anthracycline-associated resistance ARX; AltName: Full=Ubiquitin-like 1-activating enzyme E1B; AltName: Full=Ubiquitin-like modifier-activating enzyme 2;+++[K7EPL2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000467433}; Flags: Fragment;+++[K7ES38_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468538};+++[K7ESK7_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468756}; Flags: Fragment;+++[U3KQ55_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475565};+++[U3KQ93_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475656};"]
[10055,"'SAE1'",1021,1268,1328,1205.66666666667,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0031510///SUMO activating enzyme complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019948///SUMO activating enzyme activity+++GO:0043008///ATP-dependent protein binding+++GO:0044388///small protein activating enzyme binding+++GO:0008047///enzyme activator activity+++GO:0016874///ligase activity+++GO:0046982///protein heterodimerization activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0008022///protein C-terminus binding+++GO:0004839///ubiquitin activating enzyme activity","GO:0006464///cellular protein modification process+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0043085///positive regulation of catalytic activity","SUMO1 activating enzyme subunit 1","[SAE1_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 1; AltName: Full=Ubiquitin-like 1-activating enzyme E1A; Contains: RecName: Full=SUMO-activating enzyme subunit 1, N-terminally processed;+++[A0A024R0R4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_b {ECO:0000313|EMBL:EAW57462.1};+++[B3KNJ4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW57460.1}; SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000398818}; SubName: Full=cDNA FLJ14689 fis, clone NT2RP2005204, highly similar to Ubiquitin-like 1-activating enzyme E1A {ECO:0000313|EMBL:BAG51356.1};+++[M0QX65_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000468931}; Flags: Fragment;+++[M0QYM8_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469938}; Flags: Fragment;+++[M0QYP2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469978}; Flags: Fragment;+++[M0QZS6_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000470741};+++[M0R054_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000471010}; Flags: Fragment;+++[M0R286_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000472389}; Flags: Fragment;+++[M0R375_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000473037};"]
[10056,"'FARSB'",457,442.38,458,452.46,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0016020///membrane+++GO:0009328///phenylalanine-tRNA ligase complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding+++GO:0004826///phenylalanine-tRNA ligase activity","GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0006412///translation+++GO:0051290///protein heterotetramerization","phenylalanyl-tRNA synthetase subunit beta","[SYFB_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase beta subunit; EC=6.1.1.20 {ECO:0000269|PubMed:20223217}; AltName: Full=Phenylalanyl-tRNA synthetase beta subunit; Short=PheRS;+++[Q9BR63_HUMAN|Unreviewed]SubName: Full=FARSB protein {ECO:0000313|EMBL:AAH06502.2}; Flags: Fragment;"]
[10057,"'ABCC5'",5085,3801,3349,4078.33333333333,"01523///Antifolate resistance+++02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity","GO:0015711///organic anion transport+++GO:0055085///transmembrane transport+++GO:0030213///hyaluronan biosynthetic process+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport","ATP binding cassette subfamily C member 5","[MRP5_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 5; AltName: Full=ATP-binding cassette sub-family C member 5; AltName: Full=Multi-specific organic anion transporter C; Short=MOAT-C; AltName: Full=SMRP; AltName: Full=pABC11;+++[A5PKY6_HUMAN|Unreviewed]SubName: Full=ABCC5 protein {ECO:0000313|EMBL:AAI42671.1}; SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404809};+++[C9JZL5_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000399726}; Flags: Fragment;+++[E9PET4_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000390911};+++[F8WCY8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000403510};+++[F8WDH3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000409913};+++[H7C271_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404302}; Flags: Fragment;"]
[10058,"'ABCB6'",155,155,166,158.666666666667,"02010///ABC transporters","H00232///Hereditary stomatocytosis (HSt)+++H01027///Anophthalmia and microphthalmia (A/M)+++H02001///Familial pseudohyperkalemia",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005740///mitochondrial envelope+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005739///mitochondrion+++GO:0031307///integral component of mitochondrial outer membrane","GO:0015232///heme transporter activity+++GO:0020037///heme binding+++GO:0000166///nucleotide binding+++GO:0015562///efflux transmembrane transporter activity+++GO:0015439///heme-transporting ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0016887///ATPase activity","GO:0015886///heme transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007420///brain development+++GO:0055085///transmembrane transport+++GO:0043588///skin development+++GO:0006779///porphyrin-containing compound biosynthetic process","ATP binding cassette subfamily B member 6 (Langereis blood group)","[ABCB6_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family B member 6, mitochondrial; AltName: Full=Mitochondrial ABC transporter 3; Short=Mt-ABC transporter 3; AltName: Full=P-glycoprotein-related protein; AltName: Full=Ubiquitously-expressed mammalian ABC half transporter;+++[A0A024R436_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6, isoform CRA_f {ECO:0000313|EMBL:EAW70701.1};+++[A0A1D9ITY9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6 {ECO:0000313|EMBL:AOZ15555.1}; Flags: Fragment;+++[H7BXK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000295750}; Flags: Fragment;+++[H7C049_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000392988}; Flags: Fragment;+++[H7C1R6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000401811}; Flags: Fragment;+++[H7C245_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000404006}; Flags: Fragment;+++[H7C3Z0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000414646}; Flags: Fragment;+++[U3TD89_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91502.1}; Flags: Fragment;+++[U3TGG4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91501.2}; Flags: Fragment;+++[U3THN0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91500.2};+++[U3THP2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91503.1}; Flags: Fragment;+++[U3TJJ6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91499.1}; Flags: Fragment;+++[U3TJK0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91504.1}; Flags: Fragment;"]
[10059,"'DNM1L'",903,891.01,827.99,874,"04214///Apoptosis - fly+++04217///Necroptosis+++04668///TNF signaling pathway+++04621///NOD-like receptor signaling pathway+++04139///Mitophagy - yeast","H01900///Encephalopathy due to defective mitochondrial and peroxisomal fission","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R02918///L-Tyrosine:tRNA(Tyr) ligase (AMP-forming) ATP + L-Tyrosine + tRNA(Tyr) <=> AMP + Diphosphate + L-Tyrosyl-tRNA(Tyr)","GO:0045202///synapse+++GO:0099073///mitochondrion-derived vesicle+++GO:0098835///presynaptic endocytic zone membrane+++GO:0032991///protein-containing complex+++GO:0030672///synaptic vesicle membrane+++GO:0005874///microtubule+++GO:0031966///mitochondrial membrane+++GO:0030054///cell junction+++GO:0005777///peroxisome+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005905///clathrin-coated pit+++GO:0012505///endomembrane system+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0099503///secretory vesicle+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005903///brush border+++GO:0098794///postsynapse","GO:0003924///GTPase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0008289///lipid binding+++GO:0005525///GTP binding+++GO:0042803///protein homodimerization activity+++GO:0051433///BH2 domain binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0030276///clathrin binding+++GO:0008017///microtubule binding+++GO:0030742///GTP-dependent protein binding","GO:0012501///programmed cell death+++GO:0090141///positive regulation of mitochondrial fission+++GO:0043547///positive regulation of GTPase activity+++GO:0048488///synaptic vesicle endocytosis+++GO:0032459///regulation of protein oligomerization+++GO:0097194///execution phase of apoptosis+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:1904579///cellular response to thapsigargin+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0007005///mitochondrion organization+++GO:0090149///mitochondrial membrane fission+++GO:0070584///mitochondrion morphogenesis+++GO:0070585///protein localization to mitochondrion+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0036466///synaptic vesicle recycling via endosome+++GO:1990910///response to hypobaric hypoxia+++GO:0008637///apoptotic mitochondrial changes+++GO:1900063///regulation of peroxisome organization+++GO:0000266///mitochondrial fission+++GO:0048312///intracellular distribution of mitochondria+++GO:0061025///membrane fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0050714///positive regulation of protein secretion+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0016559///peroxisome fission+++GO:0060047///heart contraction+++GO:2000302///positive regulation of synaptic vesicle exocytosis+++GO:0007029///endoplasmic reticulum organization+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:0071396///cellular response to lipid+++GO:1905395///response to flavonoid+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0006897///endocytosis+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0051260///protein homooligomerization+++GO:0001836///release of cytochrome c from mitochondria+++GO:1903578///regulation of ATP metabolic process+++GO:0051259///protein complex oligomerization+++GO:0051289///protein homotetramerization+++GO:0070266///necroptotic process+++GO:0043065///positive regulation of apoptotic process","dynamin 1 like","[DNM1L_HUMAN|Reviewed]RecName: Full=Dynamin-1-like protein; EC=3.6.5.5; AltName: Full=Dnm1p/Vps1p-like protein; Short=DVLP; AltName: Full=Dynamin family member proline-rich carboxyl-terminal domain less; Short=Dymple; AltName: Full=Dynamin-like protein; AltName: Full=Dynamin-like protein 4; AltName: Full=Dynamin-like protein IV; Short=HdynIV; AltName: Full=Dynamin-related protein 1;+++[B4DDQ3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000396030}; SubName: Full=cDNA FLJ59840, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG56814.1};+++[B4DPZ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000390090}; SubName: Full=cDNA FLJ59948, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG60761.1};+++[B4DYR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56381, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG63828.1};+++[D3DUW5_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_c {ECO:0000313|EMBL:EAW88523.1};+++[D3DUW6_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_f {ECO:0000313|EMBL:EAW88527.1};+++[D3DUW7_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_a {ECO:0000313|EMBL:EAW88525.1};+++[F8VR28_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000450401};+++[F8VUJ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447845}; Flags: Fragment;+++[F8VYL3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448936};+++[F8VZ52_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447788}; Flags: Fragment;+++[F8W1W3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447013}; Flags: Fragment;+++[G8JLD5_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000350948};+++[H0YHY4_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448105}; Flags: Fragment;+++[H0YI79_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448802}; Flags: Fragment;+++[Q32Q67_HUMAN|Unreviewed]SubName: Full=DNM1L protein {ECO:0000313|EMBL:AAI07764.1}; Flags: Fragment;"]
[1006,"'CDH8'",185,248,133,188.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0043083///synaptic cleft+++GO:0097060///synaptic membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043679///axon terminus+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0016342///catenin complex","GO:0042802///identical protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding","GO:0007268///chemical synaptic transmission+++GO:0007043///cell-cell junction assembly+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0009409///response to cold+++GO:0050807///regulation of synapse organization+++GO:0035249///synaptic transmission, glutamatergic+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 8","[CADH8_HUMAN|Reviewed]RecName: Full=Cadherin-8; Flags: Precursor;+++[J3KRI5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462018};+++[J3KT81_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462847}; Flags: Fragment;+++[J3KTG8_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462976}; Flags: Fragment;+++[J3QKW5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463266};+++[J3QLE6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463511};+++[L8E7B0_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43150.1};+++[L8E8U5_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43151.1};+++[Q3LID3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla04261 {ECO:0000313|EMBL:BAE45735.1}; Flags: Fragment;+++[X6R3Y6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000299345};"]
[10060,"'ABCC9'",421.86,359.41,387.28,389.516666666667,"02010///ABC transporters","H00294///Dilated cardiomyopathy (DCM)+++H00731///Atrial fibrillation",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0042383///sarcolemma+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0008282///inward rectifying potassium channel","GO:0044325///ion channel binding+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0015459///potassium channel regulator activity+++GO:0008281///sulfonylurea receptor activity+++GO:0005524///ATP binding+++GO:0005267///potassium channel activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005215///transporter activity","GO:1990573///potassium ion import across plasma membrane+++GO:0055085///transmembrane transport+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0006813///potassium ion transport+++GO:0051607///defense response to virus+++GO:0042493///response to drug","ATP binding cassette subfamily C member 9","[ABCC9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family C member 9; AltName: Full=Sulfonylurea receptor 2;+++[A0A024RAV7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW96456.1};+++[G3V1N6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000442604}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_a {ECO:0000313|EMBL:EAW96452.1};+++[H0YFV4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000440521}; Flags: Fragment;+++[K4DI86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_e {ECO:0000313|EMBL:EAW96458.1};+++[Q8N4N7_HUMAN|Unreviewed]SubName: Full=ABCC9 protein {ECO:0000313|EMBL:AAH33804.1}; SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000317518};"]
[10061,"'ABCF2'",1249,1363,1392,1334.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005740///mitochondrial envelope+++GO:0000786///nucleosome+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0005215///transporter activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity",null,"ATP binding cassette subfamily F member 2","[ABCF2_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family F member 2; AltName: Full=Iron-inhibited ABC transporter 2;+++[A0A090N7X1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24508.1};+++[A0A090N7Y2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24507.1};+++[C9JHK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000395785}; Flags: Fragment;+++[C9JZV3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000419720}; Flags: Fragment;+++[L0R4T3_HUMAN|Unreviewed]RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};"]
[10062,"'NR1H3'",74,82,81,79,"03320///PPAR signaling pathway+++05160///Hepatitis C+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease (NAFLD)",{"$nulls":3},"GO:0005634///nucleus+++GO:0043235///receptor complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0004879///nuclear receptor activity+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0038023///signaling receptor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003713///transcription coactivator activity+++GO:0015485///cholesterol binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0032810///sterol response element binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity","GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010887///negative regulation of cholesterol storage+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0090341///negative regulation of secretion of lysosomal enzymes+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0050728///negative regulation of inflammatory response+++GO:0042632///cholesterol homeostasis+++GO:2000325///regulation of nuclear receptor transcription coactivator activity+++GO:0055092///sterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0055088///lipid homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0048550///negative regulation of pinocytosis+++GO:0043031///negative regulation of macrophage activation+++GO:0045861///negative regulation of proteolysis+++GO:0010875///positive regulation of cholesterol efflux+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032570///response to progesterone+++GO:0043277///apoptotic cell clearance+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032369///negative regulation of lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0070328///triglyceride homeostasis+++GO:0044255///cellular lipid metabolic process","nuclear receptor subfamily 1 group H member 3","[NR1H3_HUMAN|Reviewed]RecName: Full=Oxysterols receptor LXR-alpha; AltName: Full=Liver X receptor alpha; AltName: Full=Nuclear receptor subfamily 1 group H member 3;+++[B4DXU5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56172, highly similar to Oxysterols receptor LXR-alpha {ECO:0000313|EMBL:BAG63507.1};+++[B5MBY7_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000385073};+++[B6ZGS8_HUMAN|Unreviewed]SubName: Full=Liver X receptor alpha {ECO:0000313|EMBL:BAH02289.1};+++[C9J2C8_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000412636}; Flags: Fragment;+++[C9J4R0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000391005}; Flags: Fragment;+++[C9JBS2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403696}; Flags: Fragment;+++[C9JCS0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000415591}; Flags: Fragment;+++[C9JEC2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000396132}; Flags: Fragment;+++[C9JJ16_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403798}; Flags: Fragment;+++[C9JTS4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000413095}; Flags: Fragment;+++[E9PID2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000432073};+++[E9PLL4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000433271};+++[E9PPA1_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000434650}; Flags: Fragment;+++[F1D8N1_HUMAN|Unreviewed]SubName: Full=Liver X nuclear receptor alpha variant 1 {ECO:0000313|EMBL:ADZ17330.1};+++[F8WC63_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000406692};+++[F8WEY6_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000407716};"]
[10063,"'COX17'",149,153,186,162.666666666667,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00154///Cytochrome c oxidase",null,"GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0016531///copper chaperone activity+++GO:0046872///metal ion binding+++GO:0005507///copper ion binding+++GO:1903136///cuprous ion binding+++GO:0005515///protein binding","GO:1904960///positive regulation of cytochrome-c oxidase activity+++GO:0006825///copper ion transport+++GO:0006091///generation of precursor metabolites and energy+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation","cytochrome c oxidase copper chaperone COX17","[COX17_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase copper chaperone;+++[C9J8T6_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417651}; SubName: Full=HCG2022684, isoform CRA_b {ECO:0000313|EMBL:EAW79546.1};+++[H7C4E5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417120}; Flags: Fragment;+++[H7C5P5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000420406}; Flags: Fragment;"]
[100631383,"'FAM47E-STBD1'",35.97,69,22.24,42.4033333333333,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"FAM47E-STBD1 readthrough","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[D6RA91_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000423044}; Flags: Fragment;+++[F6W5V1_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000425528};"]
[100652748,"'TIMM23B'",191.62,181.35,198.14,190.37,"04212///Longevity regulating pathway - worm",{"$nulls":3},"GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005575///cellular_component+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0008320///protein transmembrane transporter activity","GO:0006886///intracellular protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0008150///biological_process+++GO:0015031///protein transport","translocase of inner mitochondrial membrane 23 homolog B","[TI23B_HUMAN|Reviewed]RecName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B;+++[B4DDK6_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000389331}; SubName: Full=cDNA FLJ60010, moderately similar to Mitochondrial import inner membrane translocase subunit Tim23 {ECO:0000313|EMBL:BAG56767.1};+++[M0QZG8_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000470535};+++[S4R2X5_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000473724};"]
[100652777,"'LOC100652777'",0,2.47,1.15,1.20666666666667,"04014///Ras signaling pathway+++00592///alpha-Linolenic acid metabolism+++04972///Pancreatic secretion+++04975///Fat digestion and absorption+++00590///Arachidonic acid metabolism+++00565///Ether lipid metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++04270///Vascular smooth muscle contraction+++00591///Linoleic acid metabolism+++00564///Glycerophospholipid metabolism",null,null,"R07387///plasmanylcholine 2-acylhydrolase 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate+++R01317///phosphatidylcholine 2-acylhydrolase Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate+++R07064///phosphatidylcholine 2-acylhydrolase Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate+++R02053///phosphatidylethanolamine 2-acylhydrolase Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid+++R07859///Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid+++R01315///phosphatidylcholine 2-acylhydrolase Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid+++R07379///plasmenylethanolamine 2-acylhydrolase O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate","GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0005509///calcium ion binding+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0004620///phospholipase activity+++GO:0004623///phospholipase A2 activity","GO:0016042///lipid catabolic process+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0036149///phosphatidylinositol acyl-chain remodeling+++GO:0090238///positive regulation of arachidonic acid secretion+++GO:0032308///positive regulation of prostaglandin secretion+++GO:0051977///lysophospholipid transport+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0019369///arachidonic acid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0010884///positive regulation of lipid storage+++GO:0042632///cholesterol homeostasis+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0090370///negative regulation of cholesterol efflux+++GO:0050482///arachidonic acid secretion+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0043030///regulation of macrophage activation+++GO:0007411///axon guidance","group 10 secretory phospholipase A2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PA2GF_HUMAN|diamond]RecName: Full=Group IIF secretory phospholipase A2; Short=GIIF sPLA2; Short=sPLA2-IIF; EC=3.1.1.4; AltName: Full=Phosphatidylcholine 2-acylhydrolase 2F; Flags: Precursor;+++[PA2GX_HUMAN|diamond]RecName: Full=Group 10 secretory phospholipase A2; EC=3.1.1.4; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor;+++[PA2GX_MOUSE|diamond]RecName: Full=Group 10 secretory phospholipase A2; EC=3.1.1.4; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor;+++[PA2GX_RAT|diamond]RecName: Full=Group 10 secretory phospholipase A2; EC=3.1.1.4; AltName: Full=Group X secretory phospholipase A2; Short=GX sPLA2; Short=sPLA2-X; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10; Flags: Precursor;+++[PA2V_MEIAT|diamond]RecName: Full=Phospholipase A2 {ECO:0000303|PubMed:28366739}; Short=PLA2 {ECO:0000303|PubMed:28366739}; EC=3.1.1.4; AltName: Full=Phosphatidylcholine 2-acylhydrolase 10 {ECO:0000250|UniProtKB:O15496}; Flags: Precursor;"]
[100652824,"'KIAA2012'",2,0,1,1,"05225///Hepatocellular carcinoma+++04390///Hippo signaling pathway+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04150///mTOR signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05166///HTLV-I infection+++05165///Human papillomavirus infection+++04916///Melanogenesis+++04310///Wnt signaling pathway+++05224///Breast cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer","H00048///Hepatocellular carcinoma+++H00031///Breast cancer","M00677///Wnt signaling",null,"GO:0055038///recycling endosome membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0030165///PDZ domain binding+++GO:0042813///Wnt-activated receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017147///Wnt-protein binding+++GO:0005109///frizzled binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding","GO:0033077///T cell differentiation in thymus+++GO:0019827///stem cell population maintenance+++GO:0048103///somatic stem cell division+++GO:0030182///neuron differentiation+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0042327///positive regulation of phosphorylation+++GO:0060231///mesenchymal to epithelial transition+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0046330///positive regulation of JNK cascade+++GO:2000726///negative regulation of cardiac muscle cell differentiation+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0071300///cellular response to retinoic acid+++GO:0060070///canonical Wnt signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0042666///negative regulation of ectodermal cell fate specification","KIAA2012","[K2012_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA2012 {ECO:0000305};+++[A0A1B0GV91_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000490419}; Flags: Fragment;+++[H7C5G6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000419834};"]
[100652901,"'LOC100652901'",41.8,31,10,27.6,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0010494///cytoplasmic stress granule","GO:0003727///single-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding","GO:0032197///transposition, RNA-mediated","uncharacterized LOC100652901","[Q6ZNX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26942 fis, clone RCT07464 {ECO:0000313|EMBL:BAC85354.1};"]
[100653133,"'LOC100653133'",1,0,4,1.66666666666667,{"$nulls":7},"golgin subfamily A member 6-like protein 1","[GG6L1_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 1;+++[GG6L2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 2;+++[GG6L6_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 6;+++[GG6L7_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 7 {ECO:0000305};+++[GG6LV_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};"]
[100653515,"'CEP295NL'",12,5,3,6.66666666666667,{"$nulls":4},"GO:0005929///cilium+++GO:0042995///cell projection","GO:0008191///metalloendopeptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity","CEP295 N-terminal like","[C295L_HUMAN|Reviewed]RecName: Full=CEP295 N-terminal-like protein {ECO:0000305}; AltName: Full=KIAA1731 N-terminal like protein {ECO:0000312|HGNC:HGNC:44659};+++[K7EL90_HUMAN|Unreviewed]SubName: Full=CEP295 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000465968}; Flags: Fragment;"]
[10066,"'SCAMP2'",2250,2788,2982,2673.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0055038///recycling endosome membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0032588///trans-Golgi network membrane+++GO:0030133///transport vesicle","GO:0005515///protein binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","secretory carrier membrane protein 2","[SCAM2_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 2; Short=Secretory carrier membrane protein 2;+++[A0A140VK92_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[A8K769_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BMN2_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BN93_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BPL9_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BQW2_HUMAN|Unreviewed]SubName: Full=Secretory carrier-associated membrane protein 2 {ECO:0000313|Ensembl:ENSP00000455963};+++[H3BUB6_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BV04_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[Q6IBK3_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};"]
[10067,"'SCAMP3'",2393,2430,2552,2458.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032588///trans-Golgi network membrane","GO:0031625///ubiquitin protein ligase binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","secretory carrier membrane protein 3","[SCAM3_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 3; Short=Secretory carrier membrane protein 3;+++[Q6FHJ5_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;"]
[10068,"'IL18BP'",88,107,98,97.6666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0042007///interleukin-18 binding+++GO:0048019///receptor antagonist activity","GO:0070301///cellular response to hydrogen peroxide+++GO:0032496///response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor+++GO:0042088///T-helper 1 type immune response+++GO:0071345///cellular response to cytokine stimulus+++GO:1900116///extracellular negative regulation of signal transduction+++GO:0035655///interleukin-18-mediated signaling pathway","interleukin 18 binding protein","[I18BP_HUMAN|Reviewed]RecName: Full=Interleukin-18-binding protein; Short=IL-18BP; AltName: Full=Tadekinig-alfa; Flags: Precursor;+++[A0A024R5G2_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_d {ECO:0000313|EMBL:EAW74817.1};+++[A0A024R5I1_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_c {ECO:0000313|EMBL:EAW74820.1};+++[A0A024R5M7_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_b {ECO:0000313|EMBL:EAW74819.1};+++[G3V1C5_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW74812.1}; SubName: Full=Interleukin-18-binding protein {ECO:0000313|Ensembl:ENSP00000434717};"]
[10069,"'RWDD2B'",165,167,233,188.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","RWD domain containing 2B","[RWD2B_HUMAN|Reviewed]RecName: Full=RWD domain-containing protein 2B;"]
[10071,"'MUC12'",5,12,2,6.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0001558///regulation of cell growth+++GO:0016266///O-glycan processing+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","mucin 12, cell surface associated","[MUC12_HUMAN|Reviewed]RecName: Full=Mucin-12; Short=MUC-12; AltName: Full=Mucin-11; Short=MUC-11; Flags: Precursor;+++[A1L198_HUMAN|Unreviewed]SubName: Full=MUC12 protein {ECO:0000313|EMBL:AAI27878.1}; Flags: Fragment;+++[H7BXN1_HUMAN|Unreviewed]SubName: Full=Mucin-12 {ECO:0000313|Ensembl:ENSP00000306919}; Flags: Fragment;+++[L8E898_HUMAN|Unreviewed]SubName: Full=Alternative protein MUC12 {ECO:0000313|EMBL:CCQ42956.1};"]
[10072,"'DPP3'",922,1059,1193,1058,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016607///nuclear speck","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004177///aminopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008237///metallopeptidase activity+++GO:0008239///dipeptidyl-peptidase activity","GO:0006508///proteolysis","dipeptidyl peptidase 3","[DPP3_HUMAN|Reviewed]RecName: Full=Dipeptidyl peptidase 3; EC=3.4.14.4 {ECO:0000269|PubMed:11209758, ECO:0000269|PubMed:1515063, ECO:0000269|PubMed:3233187, ECO:0000269|PubMed:9425109}; AltName: Full=Dipeptidyl aminopeptidase III; AltName: Full=Dipeptidyl arylamidase III; AltName: Full=Dipeptidyl peptidase III; Short=DPP III; AltName: Full=Enkephalinase B;+++[E9PKK8_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000431606}; Flags: Fragment;+++[E9PNX5_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000437101}; Flags: Fragment;+++[E9PPK9_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000432618}; Flags: Fragment;+++[E9PQ14_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000434518}; Flags: Fragment;+++[E9PQF2_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000436820}; Flags: Fragment;+++[G3V180_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[G3V1D3_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[Q5JPB8_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};"]
[10073,"'SNUPN'",154,158,153,155,"03013///RNA transport",{"$nulls":3},"GO:0005829///cytosol+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0061608///nuclear import signal receptor activity+++GO:0005515///protein binding","GO:0006606///protein import into nucleus+++GO:0061015///snRNA import into nucleus+++GO:0000387///spliceosomal snRNP assembly+++GO:0051170///import into nucleus","snurportin 1","[SPN1_HUMAN|Reviewed]RecName: Full=Snurportin-1; AltName: Full=RNA U transporter 1;+++[H3BQR0_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000455894}; Flags: Fragment;+++[H3BRI5_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456260}; Flags: Fragment;+++[H3BSK1_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456742}; Flags: Fragment;+++[H3BTA6_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457093}; Flags: Fragment;+++[H3BUB4_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457562}; Flags: Fragment;"]
[10075,"'HUWE1'",9380,9317,7057,8584.66666666667,"04120///Ubiquitin mediated proteolysis","H00658///Syndromic X-linked mental retardation",null,null,"GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0003723///RNA binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006281///DNA repair+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0043312///neutrophil degranulation+++GO:0006284///base-excision repair+++GO:0000209///protein polyubiquitination+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016574///histone ubiquitination","HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase","[HUWE1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase HUWE1; EC=2.3.2.26; AltName: Full=ARF-binding protein 1; Short=ARF-BP1; AltName: Full=HECT, UBA and WWE domain-containing protein 1; AltName: Full=HECT-type E3 ubiquitin transferase HUWE1; AltName: Full=Homologous to E6AP carboxyl terminus homologous protein 9; Short=HectH9; AltName: Full=Large structure of UREB1; Short=LASU1; AltName: Full=Mcl-1 ubiquitin ligase E3; Short=Mule; AltName: Full=Upstream regulatory element-binding protein 1; Short=URE-B1; Short=URE-binding protein 1;+++[A0A024R9U8_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW93163.1};+++[A0A024R9W5_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW93166.1};+++[A0A024R9Y3_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW93165.1};+++[A0A087X146_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000483891}; Flags: Fragment;+++[A0A087X1S3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000484417}; Flags: Fragment;+++[A0A1B0GXC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000413651}; Flags: Fragment;+++[H0Y659_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000403236}; Flags: Fragment;+++[L8E996_HUMAN|Unreviewed]SubName: Full=Alternative protein HUWE1 {ECO:0000313|EMBL:CCQ43744.1};+++[Q3B7K0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAI07577.1}; Flags: Fragment;+++[Q5H924_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42656.1}; Flags: Fragment;+++[Q5H935_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42644.1}; Flags: Fragment;+++[Q5H962_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42353.1};+++[Q5H963_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42352.1}; Flags: Fragment;+++[Q5H964_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42351.1}; Flags: Fragment;+++[Q8IWJ0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAH38184.1}; Flags: Fragment;"]
[10076,"'PTPRU'",2428,3008,2637,2691,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:0030027///lamellipodium+++GO:0098978///glutamatergic synapse+++GO:0005911///cell-cell junction+++GO:0099061///integral component of postsynaptic density membrane+++GO:0016324///apical plasma membrane+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0098982///GABA-ergic synapse+++GO:0030426///growth cone+++GO:0005887///integral component of plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0008013///beta-catenin binding+++GO:0017147///Wnt-protein binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0016787///hydrolase activity","GO:0034109///homotypic cell-cell adhesion+++GO:0016311///dephosphorylation+++GO:0031100///animal organ regeneration+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0007185///transmembrane receptor protein tyrosine phosphatase signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0032835///glomerulus development+++GO:0002548///monocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0034394///protein localization to cell surface+++GO:0007155///cell adhesion+++GO:0050807///regulation of synapse organization+++GO:0006470///protein dephosphorylation+++GO:0030154///cell differentiation+++GO:0010977///negative regulation of neuron projection development+++GO:0030032///lamellipodium assembly+++GO:0007411///axon guidance+++GO:0030336///negative regulation of cell migration+++GO:0090260///negative regulation of retinal ganglion cell axon guidance+++GO:0003105///negative regulation of glomerular filtration+++GO:0003093///regulation of glomerular filtration+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0008285///negative regulation of cell proliferation+++GO:0036060///slit diaphragm assembly","protein tyrosine phosphatase, receptor type U","[PTPRU_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase U; Short=R-PTP-U; EC=3.1.3.48; AltName: Full=Pancreatic carcinoma phosphatase 2; Short=PCP-2; AltName: Full=Protein-tyrosine phosphatase J; Short=PTP-J; Short=hPTP-J; AltName: Full=Protein-tyrosine phosphatase pi; Short=PTP pi; AltName: Full=Protein-tyrosine phosphatase receptor omicron; Short=PTP-RO; AltName: Full=Receptor-type protein-tyrosine phosphatase psi; Short=R-PTP-psi; Flags: Precursor;+++[H0YH11_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[H0YH60_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[L8ECC6_HUMAN|Unreviewed]SubName: Full=Alternative protein PTPRU {ECO:0000313|EMBL:CCQ43332.1};+++[Q9P0U2_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase {ECO:0000313|EMBL:AAF67472.1};"]
[10077,"'TSPAN32'",1,6,1,2.66666666666667,{"$nulls":4},"GO:0070442///integrin alphaIIb-beta3 complex+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0009986///cell surface+++GO:0031225///anchored component of membrane+++GO:0016020///membrane+++GO:0033017///sarcoplasmic reticulum membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003956///NAD(P)+-protein-arginine ADP-ribosyltransferase activity+++GO:0016740///transferase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003674///molecular_function","GO:0007010///cytoskeleton organization+++GO:0030886///negative regulation of myeloid dendritic cell activation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0007599///hemostasis+++GO:0006471///protein ADP-ribosylation+++GO:0007596///blood coagulation+++GO:0070527///platelet aggregation+++GO:0007267///cell-cell signaling+++GO:0042832///defense response to protozoan+++GO:0008285///negative regulation of cell proliferation+++GO:0018120///peptidyl-arginine ADP-ribosylation+++GO:0050688///regulation of defense response to virus","tetraspanin 32","[TSN32_HUMAN|Reviewed]RecName: Full=Tetraspanin-32; Short=Tspan-32; AltName: Full=Protein Phemx;+++[D3YTD1_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000405205};+++[F8WB10_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000405001};+++[F8WCN6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000343285};+++[G3XAG6_HUMAN|Unreviewed]SubName: Full=Tetraspanin 32, isoform CRA_e {ECO:0000313|EMBL:EAX02502.1}; SubName: Full=Tetraspanin-32 {ECO:0000313|Ensembl:ENSP00000370509}; Flags: Fragment;+++[Q7Z5M9_HUMAN|Unreviewed]SubName: Full=Pan-hematopoietic expression protein {ECO:0000313|EMBL:AAP76185.1};"]
[10078,"'TSSC4'",350,414,440,401.333333333333,{"$nulls":5},"GO:0005515///protein binding",null,"tumor suppressing subtransferable candidate 4","[TSSC4_HUMAN|Reviewed]RecName: Full=Protein TSSC4; AltName: Full=Tumor-suppressing STF cDNA 4 protein; AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein;+++[A0A024RCB9_HUMAN|Unreviewed]SubName: Full=Tumor suppressing subtransferable candidate 4, isoform CRA_a {ECO:0000313|EMBL:EAX02513.1};+++[A6NCC9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000370380};+++[C9JDU0_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000403475}; Flags: Fragment;+++[C9JHT9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000396925}; Flags: Fragment;+++[C9JJV1_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000416937}; Flags: Fragment;+++[E9PL88_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000431430}; Flags: Fragment;+++[E9PME3_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000435013}; Flags: Fragment;"]
[10079,"'ATP9A'",895,900,667,820.666666666667,null,"H00624///Familial cholestasis",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005769///early endosome+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding","GO:0006897///endocytosis+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport","ATPase phospholipid transporting 9A (putative)","[ATP9A_HUMAN|Reviewed]RecName: Full=Probable phospholipid-transporting ATPase IIA; EC=3.6.3.1; AltName: Full=ATPase class II type 9A;+++[A0A0A0MR22_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[B4DR18_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[Q2NLD0_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033}; Flags: Fragment;+++[Q96B35_HUMAN|Unreviewed]SubName: Full=ATP9A protein {ECO:0000313|EMBL:AAH16044.1}; Flags: Fragment;"]
[1008,"'CDH10'",185,260,199,214.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099059///integral component of presynaptic active zone membrane+++GO:0016342///catenin complex+++GO:0098982///GABA-ergic synapse+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0099060///integral component of postsynaptic specialization membrane","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","cadherin 10","[CAD10_HUMAN|Reviewed]RecName: Full=Cadherin-10; AltName: Full=T2-cadherin; Flags: Precursor;+++[D6RJG0_HUMAN|Unreviewed]SubName: Full=Cadherin-10 {ECO:0000313|Ensembl:ENSP00000425653};+++[L8ECD4_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH10 {ECO:0000313|EMBL:CCQ43372.1};+++[X5D8X5_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform A {ECO:0000313|EMBL:AHW56448.1}; SubName: Full=Cadherin 10, type 2 (T2-cadherin) {ECO:0000313|EMBL:EAX10742.1}; Flags: Fragment;+++[X5DNG6_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform B {ECO:0000313|EMBL:AHW56446.1}; Flags: Fragment;+++[X5DQT8_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform C {ECO:0000313|EMBL:AHW56447.1}; Flags: Fragment;"]
[10081,"'PDCD7'",281,253,200,244.666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005689///U12-type spliceosomal complex",null,"GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0051384///response to glucocorticoid+++GO:0000398///mRNA splicing, via spliceosome","programmed cell death 7","[PDCD7_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 7; AltName: Full=ES18; Short=hES18;+++[A3KMF9_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAI31705.1}; Flags: Fragment;+++[H3BT73_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 7 {ECO:0000313|Ensembl:ENSP00000457053}; Flags: Fragment;+++[Q569I4_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAH92464.1}; Flags: Fragment;+++[Q6IEG3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 7, isoform CRA_a {ECO:0000313|EMBL:EAW77713.1}; SubName: Full=U11/U12 snRNP 59K {ECO:0000313|EMBL:DAA05494.1};"]
[10082,"'GPC6'",1512,1875,1249,1545.33333333333,null,"H02154///Omodysplasia+++H00493///Heparan sulfate proteoglycan gene defects",null,null,"GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0005634///nucleus+++GO:0062023///collagen-containing extracellular matrix+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0046658///anchored component of plasma membrane+++GO:0043202///lysosomal lumen+++GO:0005796///Golgi lumen+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding+++GO:1904929///coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway","GO:0006027///glycosaminoglycan catabolic process+++GO:0001523///retinoid metabolic process+++GO:0016477///cell migration+++GO:0009966///regulation of signal transduction+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane","glypican 6","[GPC6_HUMAN|Reviewed]RecName: Full=Glypican-6; Contains: RecName: Full=Secreted glypican-6; Flags: Precursor;+++[A0A087WT82_HUMAN|Unreviewed]SubName: Full=Glypican-6 {ECO:0000313|Ensembl:ENSP00000477667};"]
[100820829,"'MYZAP'",3,17,15,11.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0030018///Z disc","GO:0005515///protein binding","GO:0035556///intracellular signal transduction","myocardial zonula adherens protein","[MYZAP_HUMAN|Reviewed]RecName: Full=Myocardial zonula adherens protein; AltName: Full=GRINL1A upstream protein; Short=Gup; Flags: Precursor;+++[A0A024R5W4_HUMAN|Unreviewed]SubName: Full=HCG40688, isoform CRA_a {ECO:0000313|EMBL:EAW77523.1};+++[H0YCD3_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000431396}; Flags: Fragment;+++[H3BTD5_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000457126}; Flags: Fragment;"]
[10083,"'USH1C'",1,0,0,0.333333333333333,null,"H00605///Deafness, autosomal recessive+++H00779///Usher syndrome (US)",null,null,"GO:0002142///stereocilia ankle link complex+++GO:0045202///synapse+++GO:0005903///brush border+++GO:0005902///microvillus+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0045177///apical part of cell+++GO:0032420///stereocilium+++GO:0005886///plasma membrane+++GO:0001917///photoreceptor inner segment+++GO:0032391///photoreceptor connecting cilium+++GO:0005737///cytoplasm+++GO:0001750///photoreceptor outer segment+++GO:0002141///stereocilia ankle link+++GO:0032426///stereocilium tip","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0030507///spectrin binding","GO:0034622///cellular protein-containing complex assembly+++GO:0050953///sensory perception of light stimulus+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:0042472///inner ear morphogenesis+++GO:1904106///protein localization to microvillus+++GO:0045494///photoreceptor cell maintenance+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0030046///parallel actin filament bundle assembly+++GO:0007605///sensory perception of sound+++GO:1904970///brush border assembly+++GO:0032532///regulation of microvillus length+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0050957///equilibrioception+++GO:0051017///actin filament bundle assembly+++GO:0030154///cell differentiation","USH1 protein network component harmonin","[USH1C_HUMAN|Reviewed]RecName: Full=Harmonin; AltName: Full=Antigen NY-CO-38/NY-CO-37; AltName: Full=Autoimmune enteropathy-related antigen AIE-75; AltName: Full=Protein PDZ-73; AltName: Full=Renal carcinoma antigen NY-REN-3; AltName: Full=Usher syndrome type-1C protein;+++[A0A0S2Z4U9_HUMAN|Unreviewed]SubName: Full=Usher syndrome 1C (Autosomal recessive, severe), isoform CRA_d {ECO:0000313|EMBL:EAW68434.1}; SubName: Full=Usher syndrome 1C isoform 2 {ECO:0000313|EMBL:ALQ33957.1}; Flags: Fragment;+++[A0A0S2Z4V1_HUMAN|Unreviewed]SubName: Full=Usher syndrome 1C (Autosomal recessive, severe), isoform CRA_a {ECO:0000313|EMBL:EAW68431.1}; SubName: Full=Usher syndrome 1C isoform 1 {ECO:0000313|EMBL:ALQ33956.1}; Flags: Fragment;+++[E9PNW1_HUMAN|Unreviewed]SubName: Full=Harmonin {ECO:0000313|Ensembl:ENSP00000437128}; Flags: Fragment;"]
[10084,"'PQBP1'",490,484,582,518.666666666667,"03040///Spliceosome","H01913///Renpenning syndrome+++H00480///Non-syndromic X-linked mental retardation","M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0010494///cytoplasmic stress granule+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071598///neuronal ribonucleoprotein granule","GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043021///ribonucleoprotein complex binding","GO:0006355///regulation of transcription, DNA-templated+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0032481///positive regulation of type I interferon production+++GO:0031175///neuron projection development+++GO:0002218///activation of innate immune response+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071360///cellular response to exogenous dsRNA+++GO:0002230///positive regulation of defense response to virus by host+++GO:0008380///RNA splicing+++GO:0051607///defense response to virus+++GO:0043484///regulation of RNA splicing+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0048814///regulation of dendrite morphogenesis","polyglutamine binding protein 1","[PQBP1_HUMAN|Reviewed]RecName: Full=Polyglutamine-binding protein 1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; Short=PQBP-1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; AltName: Full=38 kDa nuclear protein containing a WW domain {ECO:0000303|PubMed:10198427}; Short=Npw38 {ECO:0000303|PubMed:10198427}; AltName: Full=Polyglutamine tract-binding protein 1 {ECO:0000303|PubMed:10332029};+++[A0A0S2Z4V5_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33958.1}; SubName: Full=Polyglutamine binding protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW50737.1}; Flags: Fragment;+++[A0A0S2Z556_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33959.1}; Flags: Fragment;+++[H7C053_HUMAN|Unreviewed]SubName: Full=Polyglutamine-binding protein 1 {ECO:0000313|Ensembl:ENSP00000393013}; Flags: Fragment;+++[Q4VY28_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein variant 12 {ECO:0000313|EMBL:CAJ00551.1}; Flags: Fragment;"]
[10085,"'EDIL3'",5309,4425,3507,4413.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:1903561///extracellular vesicle","GO:0005201///extracellular matrix structural constituent+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0010811///positive regulation of cell-substrate adhesion","EGF like repeats and discoidin domains 3","[EDIL3_HUMAN|Reviewed]RecName: Full=EGF-like repeat and discoidin I-like domain-containing protein 3; AltName: Full=Developmentally-regulated endothelial cell locus 1 protein; AltName: Full=Integrin-binding protein DEL1; Flags: Precursor;"]
[100861412,"'FSBP'",70.43,20.32,35.85,42.2,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","fibrinogen silencer binding protein","[FSBP_HUMAN|Reviewed]RecName: Full=Fibrinogen silencer-binding protein;+++[J3KSW4_HUMAN|Unreviewed]SubName: Full=Fibrinogen silencer-binding protein {ECO:0000313|Ensembl:ENSP00000462684};"]
[100862671,"'TMEM265'",104,100,124,109.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009607///response to biotic stimulus","transmembrane protein 265","[TM265_HUMAN|Reviewed]RecName: Full=Transmembrane protein 265 {ECO:0000312|HGNC:HGNC:51241};"]
[10087,"'COL4A3BP'",733,613,515,620.333333333333,"05202///Transcriptional misregulation in cancer+++05213///Endometrial cancer+++05224///Breast cancer+++04140///Autophagy - animal+++05210///Colorectal cancer+++05220///Chronic myeloid leukemia+++05212///Pancreatic cancer+++05214///Glioma+++05216///Thyroid cancer+++04137///Mitophagy - animal+++05218///Melanoma+++05217///Basal cell carcinoma+++03460///Fanconi anemia pathway+++05226///Gastric cancer+++05225///Hepatocellular carcinoma+++05222///Small cell lung cancer+++05200///Pathways in cancer+++05223///Non-small cell lung cancer","H00773///Autosomal dominant mental retardation",null,null,"GO:0005581///collagen trimer+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005623///cell+++GO:0048471///perinuclear region of cytoplasm","GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0120017///intermembrane ceramide transfer activity+++GO:0008289///lipid binding+++GO:1902388///ceramide 1-phosphate transporter activity+++GO:0016301///kinase activity+++GO:1902387///ceramide 1-phosphate binding+++GO:0097001///ceramide binding+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0006869///lipid transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0003007///heart morphogenesis+++GO:0055088///lipid homeostasis+++GO:0001701///in utero embryonic development+++GO:0008283///cell proliferation+++GO:0006672///ceramide metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0120009///intermembrane lipid transfer+++GO:0007029///endoplasmic reticulum organization+++GO:0120012///intermembrane sphingolipid transfer+++GO:0035621///ER to Golgi ceramide transport+++GO:0035627///ceramide transport+++GO:0000902///cell morphogenesis+++GO:1902389///ceramide 1-phosphate transport+++GO:0070584///mitochondrion morphogenesis+++GO:0006936///muscle contraction+++GO:0007165///signal transduction+++GO:0006955///immune response","collagen type IV alpha 3 binding protein","[C43BP_HUMAN|Reviewed]RecName: Full=Collagen type IV alpha-3-binding protein; AltName: Full=Ceramide transfer protein {ECO:0000303|PubMed:14685229}; Short=hCERT; AltName: Full=Goodpasture antigen-binding protein; Short=GPBP; AltName: Full=START domain-containing protein 11; Short=StARD11; AltName: Full=StAR-related lipid transfer protein 11;+++[A0A024RAJ5_HUMAN|Unreviewed]SubName: Full=Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW95758.1};+++[A0A0A0MRE4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000350046}; Flags: Fragment;+++[A0A2R8Y3S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493565}; Flags: Fragment;+++[A0A2R8Y5G0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494760}; Flags: Fragment;+++[A0A2R8Y5H3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494810}; Flags: Fragment;+++[A0A2R8Y5S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494804};+++[A0A2R8Y773_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495798}; Flags: Fragment;+++[A0A2R8Y7C5_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496016};+++[A0A2R8Y7Q9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496462};+++[A0A2R8YCI0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493604};+++[A0A2R8YDX6_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495038}; Flags: Fragment;+++[A0A2R8YE18_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495172};+++[A0A2R8YE59_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494073}; Flags: Fragment;+++[A0A2R8YEA4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495430};+++[A0A2R8YEK8_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494424};+++[A0A2R8YFA1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494969}; Flags: Fragment;+++[A0A2R8YFI2_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496472};+++[A0A2U3TZL3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000369862}; Flags: Fragment;+++[H0Y9J1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000424244}; Flags: Fragment;"]
[100873985,"'MED14OS'",4,1,5,3.33333333333333,{"$nulls":7},"MED14 opposite strand","[M14OS_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein MED14OS {ECO:0000305}; AltName: Full=MED14 antisense gene protein 1 {ECO:0000305}; AltName: Full=MED14 opposite strand protein {ECO:0000312|HGNC:HGNC:40162};"]
[100885848,"'PTGES3L'",4.94,6,8,6.31333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0051879///Hsp90 protein binding+++GO:0051087///chaperone binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","prostaglandin E synthase 3 like","[PTG3L_HUMAN|Reviewed]RecName: Full=Putative protein PTGES3L; AltName: Full=Prostaglandin E synthase 3-like;+++[B9A003_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000386902};+++[C9JG77_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000404440}; Flags: Fragment;+++[H7C1Q7_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000467778}; Flags: Fragment;+++[K7N7A2_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000401675}; Flags: Fragment;"]
[100885850,"'PTGES3L-AARSD1'",25.11,5.9,0,10.3366666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004813///alanine-tRNA ligase activity","GO:0006419///alanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation","PTGES3L-AARSD1 readthrough","[AASD1_HUMAN|Reviewed]RecName: Full=Alanyl-tRNA editing protein Aarsd1; AltName: Full=Alanyl-tRNA synthetase domain-containing protein 1;+++[C9J5N1_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000386254};+++[C9JUA3_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393780}; Flags: Fragment;+++[H7C054_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393019}; Flags: Fragment;+++[L7N2F6_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000407951}; Flags: Fragment;"]
[10089,"'KCNK7'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0022841///potassium ion leak channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity","GO:0006813///potassium ion transport+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport","potassium two pore domain channel subfamily K member 7","[KCNK7_HUMAN|Reviewed]RecName: Full=Potassium channel subfamily K member 7;+++[A0A024R5B0_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_c {ECO:0000313|EMBL:EAW74415.1};+++[A0A024R5F5_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_b {ECO:0000313|EMBL:EAW74414.1};+++[H0YCM4_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000431950}; Flags: Fragment;+++[H0YEB9_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000435449}; Flags: Fragment;+++[Q3MI97_HUMAN|Unreviewed]SubName: Full=KCNK7 protein {ECO:0000313|EMBL:AAI03812.2}; Flags: Fragment;+++[Q3SYI1_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7 {ECO:0000313|EMBL:AAI03811.1};"]
[1009,"'CDH11'",1059,1488,1253,1266.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01513///Retinoblastoma",null,null,"GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0070062///extracellular exosome+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse+++GO:0005737///cytoplasm","GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding","GO:0021957///corticospinal tract morphogenesis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0001503///ossification+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050804///modulation of chemical synaptic transmission+++GO:0001501///skeletal system development","cadherin 11","[CAD11_HUMAN|Reviewed]RecName: Full=Cadherin-11; AltName: Full=OSF-4; AltName: Full=Osteoblast cadherin; Short=OB-cadherin; Flags: Precursor;+++[A0A087X227_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000484650}; Flags: Fragment;+++[H3BP26_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455120}; Flags: Fragment;+++[H3BPQ2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455420}; Flags: Fragment;+++[H3BQB5_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455697}; Flags: Fragment;+++[H3BQH2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455779}; Flags: Fragment;+++[H3BR78_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456110}; Flags: Fragment;+++[H3BSM4_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456772}; Flags: Fragment;+++[H3BUU9_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000457812};+++[Q96CZ9_HUMAN|Unreviewed]SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast) {ECO:0000313|EMBL:AAH13609.1}; SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast), isoform CRA_c {ECO:0000313|EMBL:EAW83002.1};"]
[10090,"'UST'",57,70,56,61,"00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0050770///regulation of axonogenesis+++GO:0006477///protein sulfation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030010///establishment of cell polarity","uronyl 2-sulfotransferase","[UST_HUMAN|Reviewed]RecName: Full=Uronyl 2-sulfotransferase; EC=2.8.2.-;"]
[10092,"'ARPC5'",1952,2236,2118,2102,"05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++04144///Endocytosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0034774///secretory granule lumen+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005885///Arp2/3 protein complex","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0030036///actin cytoskeleton organization+++GO:0030011///maintenance of cell polarity+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0051639///actin filament network formation+++GO:0016477///cell migration+++GO:0061024///membrane organization+++GO:0097581///lamellipodium organization+++GO:0061842///microtubule organizing center localization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0014909///smooth muscle cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0021769///orbitofrontal cortex development","actin related protein 2/3 complex subunit 5","[ARPC5_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5; AltName: Full=Arp2/3 complex 16 kDa subunit; Short=p16-ARC;+++[B1ALC0_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};+++[Q6IPM3_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};"]
[10093,"'ARPC4'",1383.39,1508.85,1813.34,1568.52666666667,"04144///Endocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton","GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0051015///actin filament binding+++GO:0030674///protein binding, bridging+++GO:0003779///actin binding","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0045010///actin nucleation+++GO:0030041///actin filament polymerization+++GO:0048013///ephrin receptor signaling pathway+++GO:0061024///membrane organization+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis","actin related protein 2/3 complex subunit 4","[ARPC4_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4; AltName: Full=Arp2/3 complex 20 kDa subunit; Short=p20-ARC;+++[F8WDD7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000395085};+++[F8WDW3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000414751};+++[R4GN08_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000473435}; Flags: Fragment;"]
[10094,"'ARPC3'",1342,1428,1651,1473.66666666667,"05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++04144///Endocytosis+++05131///Shigellosis+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0031941///filamentous actin+++GO:0061850///growth cone leading edge+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0031252///cell leading edge+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0070358///actin polymerization-dependent cell motility","actin related protein 2/3 complex subunit 3","[ARPC3_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3; AltName: Full=Arp2/3 complex 21 kDa subunit; Short=p21-ARC;+++[C9JZD1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000413221}; Flags: Fragment;+++[F8VR50_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000446598}; Flags: Fragment;+++[Q2LE71_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000256|PIRNR:PIRNR016315}; AltName: Full=Arp2/3 complex 21 kDa subunit {ECO:0000256|PIRNR:PIRNR016315};"]
[10095,"'ARPC1B'",1417,1647,1831,1631.66666666667,"05131///Shigellosis+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0036284///tubulobulbar complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0032355///response to estradiol+++GO:0043627///response to estrogen+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization","actin related protein 2/3 complex subunit 1B","[ARC1B_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1B; AltName: Full=Arp2/3 complex 41 kDa subunit; AltName: Full=p41-ARC;+++[A4D275_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};+++[C9J4Z7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000410238}; Flags: Fragment;+++[C9J6C8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398110}; Flags: Fragment;+++[C9JBJ7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398620}; Flags: Fragment;+++[C9JEY1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403324}; Flags: Fragment;+++[C9JFG9_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403211}; Flags: Fragment;+++[C9JM51_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408758}; Flags: Fragment;+++[C9JQM8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000388802}; Flags: Fragment;+++[C9JTT6_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413067}; Flags: Fragment;+++[C9K057_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413173};+++[F8VXW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000399955};+++[F8WEB3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408508};+++[L8EAG6_HUMAN|Unreviewed]SubName: Full=Alternative protein ARPC1B {ECO:0000313|EMBL:CCQ43333.1};"]
[10096,"'ACTR3'",2753,2705,2732,2730,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0035861///site of double-strand break+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0030027///lamellipodium+++GO:0005911///cell-cell junction","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005524///ATP binding+++GO:0003779///actin binding","GO:0007163///establishment or maintenance of cell polarity+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0071346///cellular response to interferon-gamma+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070358///actin polymerization-dependent cell motility+++GO:0008356///asymmetric cell division+++GO:0060271///cilium assembly+++GO:0033206///meiotic cytokinesis+++GO:0007015///actin filament organization+++GO:0061024///membrane organization+++GO:0051321///meiotic cell cycle+++GO:0051653///spindle localization+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0048013///ephrin receptor signaling pathway+++GO:0030030///cell projection organization","ARP3 actin related protein 3 homolog","[ARP3_HUMAN|Reviewed]RecName: Full=Actin-related protein 3; AltName: Full=Actin-like protein 3;+++[A0A024RAI1_HUMAN|Unreviewed]SubName: Full=ARP3 actin-related protein 3 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW95180.1};+++[B4DXW1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000444987}; SubName: Full=cDNA FLJ51148, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63684.1}; SubName: Full=cDNA FLJ52434, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63523.1}; SubName: Full=cDNA, FLJ79112, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14584.1}; SubName: Full=cDNA, FLJ79295, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14767.1};+++[F8WDR7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000403125}; Flags: Fragment;+++[F8WE84_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000394213};+++[F8WEW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000407912};"]
[10097,"'ACTR2'",2569,2626,2223,2472.66666666667,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0014069///postsynaptic density+++GO:0035861///site of double-strand break+++GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071437///invadopodium+++GO:0030027///lamellipodium+++GO:0005856///cytoskeleton+++GO:0035578///azurophil granule lumen+++GO:0098794///postsynapse+++GO:0061825///podosome core+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0042995///cell projection+++GO:0030478///actin cap","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0051015///actin filament binding+++GO:0008092///cytoskeletal protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0061024///membrane organization+++GO:0033206///meiotic cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:0007015///actin filament organization+++GO:0043312///neutrophil degranulation+++GO:0008306///associative learning+++GO:0035902///response to immobilization stress+++GO:0045471///response to ethanol+++GO:0016482///cytosolic transport+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0008356///asymmetric cell division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining+++GO:0007163///establishment or maintenance of cell polarity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0060271///cilium assembly+++GO:0051321///meiotic cell cycle+++GO:0035984///cellular response to trichostatin A+++GO:0071346///cellular response to interferon-gamma+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0051653///spindle localization","ARP2 actin related protein 2 homolog","[ARP2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2; AltName: Full=Actin-like protein 2;+++[A0A1B0GWD0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490877};+++[A0A1B0GWH0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490923};+++[F5H6T1_HUMAN|Unreviewed]SubName: Full=ARP2 actin-related protein 2 homolog (Yeast), isoform CRA_d {ECO:0000313|EMBL:EAW99914.1}; SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000437383};+++[Q8IY98_HUMAN|Unreviewed]SubName: Full=ACTR2 protein {ECO:0000313|EMBL:AAH36253.1};"]
[10098,"'TSPAN5'",954,829,795,859.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0019899///enzyme binding","GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane+++GO:0007166///cell surface receptor signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0045747///positive regulation of Notch signaling pathway","tetraspanin 5","[TSN5_HUMAN|Reviewed]RecName: Full=Tetraspanin-5; Short=Tspan-5; AltName: Full=Tetraspan NET-4; AltName: Full=Transmembrane 4 superfamily member 9;+++[B7Z317_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[D6R9N6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000423504}; Flags: Fragment;+++[D6RAR1_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000421808};+++[D6RBT5_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422548};+++[D6RGZ7_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000426248}; Flags: Fragment;+++[H0Y8W4_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422351}; Flags: Fragment;+++[Q6FHC5_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[10099,"'TSPAN3'",5759,6655,6969,6461,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway","H00287///Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0007166///cell surface receptor signaling pathway+++GO:0008150///biological_process","tetraspanin 3","[TSN3_HUMAN|Reviewed]RecName: Full=Tetraspanin-3; Short=Tspan-3; AltName: Full=Tetraspanin TM4-A; AltName: Full=Transmembrane 4 superfamily member 8;+++[H0YKJ9_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000452835};+++[H0YMH8_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000453613};+++[L8E893_HUMAN|Unreviewed]SubName: Full=Alternative protein TSPAN3 {ECO:0000313|EMBL:CCQ43334.1};"]
[100996259,"'FAM106B'",2.28,2,5.1,3.12666666666667,{"$nulls":7},"family with sequence similarity 106 member B","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[F106A_HUMAN|diamond]RecName: Full=Protein FAM106A;+++[F106C_HUMAN|diamond]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[100996318,"'LOC100996318'",4,5,3.34,4.11333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006334///nucleosome assembly","uncharacterized LOC100996318","[H2B1_BOVIN|diamond]RecName: Full=Histone H2B type 1;+++[H2B1H_HUMAN|diamond]RecName: Full=Histone H2B type 1-H; AltName: Full=Histone H2B.j; Short=H2B/j;+++[H2B1O_HUMAN|diamond]RecName: Full=Histone H2B type 1-O; AltName: Full=Histone H2B.2; AltName: Full=Histone H2B.n; Short=H2B/n;+++[H2B2B_MOUSE|diamond]RecName: Full=Histone H2B type 2-B; AltName: Full=H2b 616;+++[H2B2F_HUMAN|diamond]RecName: Full=Histone H2B type 2-F;"]
[100996379,"'LOC100996379'",0,0,2.13,0.71,"04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal+++04137///Mitophagy - animal","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0032183///SUMO binding+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0007283///spermatogenesis+++GO:0006886///intracellular protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0016567///protein ubiquitination+++GO:0006974///cellular response to DNA damage stimulus","E3 ubiquitin-protein ligase HERC2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996414,"'100996414'",43.28,34.62,45.96,41.2866666666667,{"$nulls":8},"[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[100996492,"'CTXND1'",26,12,11,16.3333333333333,null,"H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0016021///integral component of membrane+++GO:0031224///intrinsic component of membrane+++GO:0016020///membrane",null,null,"cortexin domain containing 1","[CTXD1_HUMAN|Reviewed]RecName: Full=Cortexin domain-containing 1 {ECO:0000305};"]
[100996517,"'SEC22B3'",295.5,232.55,203.29,243.78,"04145///Phagosome+++04130///SNARE interactions in vesicular transport+++05134///Legionellosis",{"$nulls":3},"GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000139///Golgi membrane+++GO:0042470///melanosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0008021///synaptic vesicle+++GO:0030133///transport vesicle","GO:0000149///SNARE binding+++GO:0019905///syntaxin binding+++GO:0005484///SNAP receptor activity","GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:1902902///negative regulation of autophagosome assembly+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0045732///positive regulation of protein catabolic process+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent","SEC22 homolog B3","[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996643,"'LOC100996643'",3,3,0,2,"00670///One carbon pool by folate+++04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005739///mitochondrion","GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0005524///ATP binding+++GO:0015267///channel activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008236///serine-type peptidase activity+++GO:0042803///protein homodimerization activity+++GO:0004180///carboxypeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity+++GO:0004329///formate-tetrahydrofolate ligase activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity","GO:0042135///neurotransmitter catabolic process+++GO:0006508///proteolysis+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0001843///neural tube closure+++GO:0006760///folic acid-containing compound metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0009113///purine nucleobase biosynthetic process+++GO:0046655///folic acid metabolic process+++GO:0015942///formate metabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0009257///10-formyltetrahydrofolate biosynthetic process","monofunctional C1-tetrahydrofolate synthase, mitochondrial-like","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[TR43B_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43B;+++[TRI43_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996693,"'LOC100996693'",4,1,5,3.33333333333333,{"$nulls":7},"CAVP-target protein-like","[A0A087WV53_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000479190};"]
[100996709,"'LOC100996709'",124.18,123.73,179.27,142.393333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore","GO:0005525///GTP binding+++GO:0008270///zinc ion binding+++GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0004181///metallocarboxypeptidase activity+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)","GO:0043984///histone H4-K16 acetylation+++GO:0015031///protein transport+++GO:0035610///protein side chain deglutamylation+++GO:0043981///histone H4-K5 acetylation+++GO:0016192///vesicle-mediated transport+++GO:0043982///histone H4-K8 acetylation","ADP-ribosylation factor-like protein 17","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};"]
[100996716,"'SEC22B2'",81.57,154.3,191.15,142.34,"04145///Phagosome+++05134///Legionellosis+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030133///transport vesicle+++GO:0042470///melanosome+++GO:0030670///phagocytic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0031201///SNARE complex+++GO:0000139///Golgi membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005789///endoplasmic reticulum membrane+++GO:0005622///intracellular+++GO:0016021///integral component of membrane","GO:0005484///SNAP receptor activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0045732///positive regulation of protein catabolic process+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0015031///protein transport+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane","SEC22 homolog B2","[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996717,"'NOTCH2NLC'",332.12,269.8,257.6,286.506666666667,"01522///Endocrine resistance+++05224///Breast cancer+++04320///Dorso-ventral axis formation+++05200///Pathways in cancer+++04919///Thyroid hormone signaling pathway+++04658///Th1 and Th2 cell differentiation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection","H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development+++GO:0045747///positive regulation of Notch signaling pathway","notch 2 N-terminal like C","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NC_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[100996720,"'LOC100996720'",126,164,172,154,{"$nulls":4},"GO:0005622///intracellular","GO:0003950///NAD+ ADP-ribosyltransferase activity",null,"uncharacterized LOC100996720","[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;"]
[100996741,"'100996741'",25,31,10,22,{"$nulls":8},"[F231A_HUMAN|diamond]RecName: Full=Putative protein FAM231AP {ECO:0000305};+++[F231B_HUMAN|diamond]RecName: Full=Putative protein FAM231BP;+++[F231C_HUMAN|diamond]RecName: Full=Protein FAM231C;+++[F231D_HUMAN|diamond]RecName: Full=Protein FAM231D;+++[F231L_HUMAN|diamond]RecName: Full=FAM231A/C-like protein LOC102723383;"]
[100996746,"'SPDYE11'",0,0,1,0.333333333333333,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E11","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE2_HUMAN|diamond]RecName: Full=Speedy protein E2;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPDE6_HUMAN|diamond]RecName: Full=Speedy protein E6;+++[SPE2B_HUMAN|diamond]RecName: Full=Speedy protein E2B;"]
[100996747,"'LOC100996747'",133.13,142.22,66.63,113.993333333333,{"$nulls":4},"GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane+++GO:0022627///cytosolic small ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0003729///mRNA binding","GO:0002181///cytoplasmic translation+++GO:0033119///negative regulation of RNA splicing","40S ribosomal protein S26","[RS26_BOVIN|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_HUMAN|diamond]RecName: Full=40S ribosomal protein S26; AltName: Full=Small ribosomal subunit protein eS26 {ECO:0000303|PubMed:24524803};+++[RS26_MACFA|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_MOUSE|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_PIG|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_RAT|diamond]RecName: Full=40S ribosomal protein S26;"]
[100996758,"'NPY4R2'",4,4,4,4,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0001602///pancreatic polypeptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017046///peptide hormone binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007218///neuropeptide signaling pathway","neuropeptide Y receptor Y4-2","[NPY4R_HUMAN|Reviewed]RecName: Full=Neuropeptide Y receptor type 4; Short=NPY4-R; AltName: Full=Pancreatic polypeptide receptor 1; Short=PP1;"]
[100996763,"'NOTCH2NLB'",434.01,291.73,290.75,338.83,"05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005112///Notch binding+++GO:0005515///protein binding","GO:0045747///positive regulation of Notch signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development","notch 2 N-terminal like B","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[A0A0B4J2B3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 14 {ECO:0000313|Ensembl:ENSP00000472124};"]
[100996792,"'LOC100996792'",1.01,1.01,1,1.00666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0004708///MAP kinase kinase activity+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity","GO:0031098///stress-activated protein kinase signaling cascade+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006954///inflammatory response+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0000187///activation of MAPK activity+++GO:0042981///regulation of apoptotic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060048///cardiac muscle contraction+++GO:0023014///signal transduction by protein phosphorylation+++GO:0007165///signal transduction+++GO:0038066///p38MAPK cascade+++GO:0032147///activation of protein kinase activity+++GO:0007346///regulation of mitotic cell cycle+++GO:0043536///positive regulation of blood vessel endothelial cell migration","dual specificity mitogen-activated protein kinase kinase 3 pseudogene","[MP2K3_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000269|PubMed:8622669}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3; AltName: Full=Stress-activated protein kinase kinase 2; Short=SAPK kinase 2; Short=SAPKK-2; Short=SAPKK2;+++[MP2K3_MOUSE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000250|UniProtKB:P46734}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3;+++[MP2K6_BOVIN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6;+++[MP2K6_DANRE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAP kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAPKK 6 {ECO:0000250|UniProtKB:P52564}; EC=2.7.12.2; AltName: Full=Mitogen-activated protein kinase kinase 3 {ECO:0000303|PubMed:10995439}; Short=zMKK3 {ECO:0000312|EMBL:BAB11809.1};+++[MP2K6_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6; AltName: Full=Stress-activated protein kinase kinase 3; Short=SAPK kinase 3; Short=SAPKK-3; Short=SAPKK3;"]
[100996842,"'LOC100996842'",20,14,17,17,"04142///Lysosome",{"$nulls":3},"GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane",null,"GO:0043312///neutrophil degranulation+++GO:0071310///cellular response to organic substance","uncharacterized LOC100996842","[CD68_HUMAN|diamond]RecName: Full=Macrosialin; AltName: Full=Gp110; AltName: CD_antigen=CD68; Flags: Precursor;+++[CD68_MOUSE|diamond]RecName: Full=Macrosialin; AltName: CD_antigen=CD68; Flags: Precursor;+++[MPU1_CRIGR|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation; Short=SL15;+++[MPU1_HUMAN|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;+++[MPU1_MOUSE|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;"]
[100996911,"'LOC100996911'",0.5,0,0,0.166666666666667,{"$nulls":4},"GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0031258///lamellipodium membrane+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0043202///lysosomal lumen+++GO:0005576///extracellular region+++GO:0016324///apical plasma membrane+++GO:0005796///Golgi lumen+++GO:0062023///collagen-containing extracellular matrix","GO:0019901///protein kinase binding","GO:0035556///intracellular signal transduction+++GO:0000187///activation of MAPK activity+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0008283///cell proliferation+++GO:0048771///tissue remodeling+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030207///chondroitin sulfate catabolic process+++GO:0008347///glial cell migration+++GO:0001525///angiogenesis+++GO:0030208///dermatan sulfate biosynthetic process","putative ubiquitin-conjugating enzyme E2Q2-like protein","[A0A024R018_HUMAN|Unreviewed]SubName: Full=HCG1818167, isoform CRA_a {ECO:0000313|EMBL:EAW55850.1};"]
[100996939,"'PYURF'",371,401,407,393,"00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis+++01100///Metabolic pathways","H01488///Hyperphosphatasia with mental retardation syndrome (HPMPS)+++H01489///Inherited glycosylphosphatidylinositol (GPI) deficiencies",null,"R05916///UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143","GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0009893///positive regulation of metabolic process+++GO:0006506///GPI anchor biosynthetic process","PIGY upstream reading frame","[PREY_HUMAN|Reviewed]RecName: Full=Protein preY, mitochondrial; AltName: Full=PIGY upstream reading frame protein; Flags: Precursor;"]
[101,"'ADAM8'",257,114,118,163,{"$nulls":4},"GO:0070821///tertiary granule membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0042581///specific granule+++GO:0032127///dense core granule membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0032010///phagolysosome+++GO:0016020///membrane+++GO:0070820///tertiary granule+++GO:0071065///alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex+++GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0002102///podosome+++GO:0035579///specific granule membrane+++GO:0071133///alpha9-beta1 integrin-ADAM8 complex","GO:0008237///metallopeptidase activity+++GO:0050839///cell adhesion molecule binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0043621///protein self-association","GO:0071456///cellular response to hypoxia+++GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:2000418///positive regulation of eosinophil migration+++GO:0043406///positive regulation of MAP kinase activity+++GO:0050714///positive regulation of protein secretion+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0045780///positive regulation of bone resorption+++GO:2000415///positive regulation of fibronectin-dependent thymocyte migration+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0001525///angiogenesis+++GO:0045089///positive regulation of innate immune response+++GO:0022617///extracellular matrix disassembly+++GO:0002693///positive regulation of cellular extravasation+++GO:2000406///positive regulation of T cell migration+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:2000309///positive regulation of tumor necrosis factor (ligand) superfamily member 11 production+++GO:0010954///positive regulation of protein processing+++GO:0043312///neutrophil degranulation+++GO:0050729///positive regulation of inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0098609///cell-cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0048247///lymphocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0022407///regulation of cell-cell adhesion","ADAM metallopeptidase domain 8","[ADAM8_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 8; Short=ADAM 8; EC=3.4.24.-; AltName: Full=Cell surface antigen MS2; AltName: CD_antigen=CD156a; Flags: Precursor;+++[H0YKZ1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000452994};+++[H0YMT6_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000453735}; Flags: Fragment;+++[Q14C66_HUMAN|Unreviewed]SubName: Full=ADAM8 protein {ECO:0000313|EMBL:AAI15405.1}; SubName: Full=cDNA, FLJ93272, highly similar to Homo sapiens a disintegrin and metalloproteinase domain 8 (ADAM8),mRNA {ECO:0000313|EMBL:BAG35688.1};"]
[1010,"'CDH12'",8,7,4,6.33333333333333,{"$nulls":4},"GO:0016342///catenin complex+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding","GO:0034332///adherens junction organization+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","cadherin 12","[CAD12_HUMAN|Reviewed]RecName: Full=Cadherin-12; AltName: Full=Brain cadherin; Short=BR-cadherin; AltName: Full=Neural type cadherin 2; Short=N-cadherin 2; Flags: Precursor;"]
[10100,"'TSPAN2'",163,135,142,146.666666666667,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0007166///cell surface receptor signaling pathway+++GO:0048709///oligodendrocyte differentiation+++GO:0014005///microglia development+++GO:0014002///astrocyte development+++GO:0006954///inflammatory response+++GO:0042552///myelination+++GO:0061564///axon development+++GO:0007420///brain development","tetraspanin 2","[TSN2_HUMAN|Reviewed]RecName: Full=Tetraspanin-2; Short=Tspan-2; AltName: Full=Tetraspan NET-3;+++[B1AKP1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[B1AKP2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[B2RD31_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};"]
[10101,"'NUBP2'",811,748,993,850.666666666667,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0005929///cilium+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0000166///nucleotide binding+++GO:0051536///iron-sulfur cluster binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0051642///centrosome localization+++GO:0001558///regulation of cell growth+++GO:0030030///cell projection organization+++GO:0006879///cellular iron ion homeostasis+++GO:0010826///negative regulation of centrosome duplication+++GO:0016226///iron-sulfur cluster assembly+++GO:0072697///protein localization to cell cortex","nucleotide binding protein 2","[NUBP2_HUMAN|Reviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000255|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000255|HAMAP-Rule:MF_03039};+++[B2RDN3_HUMAN|Unreviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000256|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000256|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000256|HAMAP-Rule:MF_03039};+++[B7Z6P0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000460079}; SubName: Full=Nucleotide binding protein 2 (MinD homolog, E. coli), isoform CRA_d {ECO:0000313|EMBL:EAW85616.1}; SubName: Full=cDNA FLJ57200, highly similar to Nucleotide-binding protein 2 {ECO:0000313|EMBL:BAH13326.1};+++[H3BMW1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454576}; Flags: Fragment;+++[H3BNF0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454815};+++[H3BNS4_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454982}; Flags: Fragment;+++[H3BQE5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455739}; Flags: Fragment;+++[H3BQR2_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455896};+++[H3BRE1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456199}; Flags: Fragment;+++[H3BRK5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456284};+++[I3L3A0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000460288}; Flags: Fragment;+++[I3L518_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461723}; Flags: Fragment;+++[I3L531_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461746}; Flags: Fragment;+++[Q2YS46_HUMAN|Unreviewed]SubName: Full=C447E6.1 (Nucleotide binding protein 1 (E.coli MinD like) ) {ECO:0000313|EMBL:CAC36077.1}; Flags: Fragment;"]
[10102,"'TSFM'",201,206,271,226,null,"H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0003746///translation elongation factor activity+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0006414///translational elongation+++GO:0070129///regulation of mitochondrial translation+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","Ts translation elongation factor, mitochondrial","[EFTS_HUMAN|Reviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135}; Flags: Precursor;+++[B4DHY8_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[C9JG32_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000390679}; Flags: Fragment;+++[C9JT21_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000389162}; Flags: Fragment;+++[E5KS95_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VPA7_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VS27_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8WCK2_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000406339};"]
[10103,"'TSPAN1'",20,22,31,24.3333333333333,"04213///Longevity regulating pathway - multiple species+++04071///Sphingolipid signaling pathway+++04218///Cellular senescence+++05166///HTLV-I infection+++04360///Axon guidance+++05161///Hepatitis B+++05212///Pancreatic cancer+++05164///Influenza A+++04666///Fc gamma R-mediated phagocytosis+++05162///Measles+++01521///EGFR tyrosine kinase inhibitor resistance+++04211///Longevity regulating pathway+++05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++04931///Insulin resistance+++05225///Hepatocellular carcinoma+++05146///Amoebiasis+++05165///Human papillomavirus infection+++04910///Insulin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04150///mTOR signaling pathway+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++05226///Gastric cancer+++05221///Acute myeloid leukemia+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++04722///Neurotrophin signaling pathway+++05210///Colorectal cancer+++04750///Inflammatory mediator regulation of TRP channels+++04072///Phospholipase D signaling pathway+++04917///Prolactin signaling pathway+++05213///Endometrial cancer+++05220///Chronic myeloid leukemia+++04152///AMPK signaling pathway+++04926///Relaxin signaling pathway+++05223///Non-small cell lung cancer+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04210///Apoptosis+++04630///Jak-STAT signaling pathway+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++05163///Human cytomegalovirus infection+++04810///Regulation of actin cytoskeleton+++04380///Osteoclast differentiation+++04012///ErbB signaling pathway+++04611///Platelet activation+++01524///Platinum drug resistance+++05160///Hepatitis C+++04014///Ras signaling pathway+++04625///C-type lectin receptor signaling pathway+++05215///Prostate cancer+++05222///Small cell lung cancer+++04070///Phosphatidylinositol signaling system+++05224///Breast cancer+++04510///Focal adhesion+++05231///Choline metabolism in cancer+++05203///Viral carcinogenesis+++04140///Autophagy - animal+++05230///Central carbon metabolism in cancer+++04930///Type II diabetes mellitus+++01522///Endocrine resistance+++04670///Leukocyte transendothelial migration+++04919///Thyroid hormone signaling pathway+++05218///Melanoma+++05142///Chagas disease (American trypanosomiasis)+++05214///Glioma+++04550///Signaling pathways regulating pluripotency of stem cells+++04370///VEGF signaling pathway+++04973///Carbohydrate digestion and absorption+++04062///Chemokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04650///Natural killer cell mediated cytotoxicity+++04620///Toll-like receptor signaling pathway+++04068///FoxO signaling pathway+++04915///Estrogen signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04024///cAMP signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++05169///Epstein-Barr virus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04725///Cholinergic synapse+++04960///Aldosterone-regulated sodium reabsorption","H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01370///SHORT syndrome","M00676///PI3K-Akt signaling","R03362///ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate+++R04545///ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate+++R05795///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate","GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane+++GO:0031982///vesicle+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0045807///positive regulation of endocytosis+++GO:0007166///cell surface receptor signaling pathway+++GO:0050821///protein stabilization+++GO:0008283///cell proliferation+++GO:0016477///cell migration","tetraspanin 1","[TSN1_HUMAN|Reviewed]RecName: Full=Tetraspanin-1; Short=Tspan-1; AltName: Full=Tetraspan NET-1; AltName: Full=Tetraspanin TM4-C;"]
[10105,"'PPIF'",863,505,608,658.666666666667,"04020///Calcium signaling pathway+++05016///Huntington's disease+++05145///Toxoplasmosis+++05012///Parkinson's disease+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005753///mitochondrial proton-transporting ATP synthase complex","GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0042277///peptide binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding","GO:0012501///programmed cell death+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0010939///regulation of necrotic cell death+++GO:0002931///response to ischemia+++GO:0043066///negative regulation of apoptotic process+++GO:0010849///regulation of proton-transporting ATPase activity, rotational mechanism+++GO:0006457///protein folding+++GO:0008637///apoptotic mitochondrial changes+++GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0032780///negative regulation of ATPase activity+++GO:2000276///negative regulation of oxidative phosphorylation uncoupler activity+++GO:0071243///cellular response to arsenic-containing substance+++GO:0006979///response to oxidative stress+++GO:1902686///mitochondrial outer membrane permeabilization involved in programmed cell death+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0071277///cellular response to calcium ion+++GO:0070301///cellular response to hydrogen peroxide+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0070266///necroptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria","peptidylprolyl isomerase F","[PPIF_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase F, mitochondrial; Short=PPIase F; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Cyclophilin D; Short=CyP-D; Short=CypD; AltName: Full=Cyclophilin F; AltName: Full=Mitochondrial cyclophilin; Short=CyP-M; AltName: Full=Rotamase F; Flags: Precursor;+++[A0A024QZS4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[H0Y548_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[R4GN99_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[101059906,"'LOC101059906'",22,20,23,21.6666666666667,"01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,null,"R07376///L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0098978///glutamatergic synapse+++GO:0000139///Golgi membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol","GO:0019003///GDP binding+++GO:0016740///transferase activity+++GO:0003924///GTPase activity+++GO:0003882///CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0005525///GTP binding+++GO:0008022///protein C-terminus binding","GO:0071480///cellular response to gamma radiation+++GO:0090303///positive regulation of wound healing+++GO:0048013///ephrin receptor signaling pathway+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007265///Ras protein signal transduction+++GO:0051291///protein heterooligomerization+++GO:0034260///negative regulation of GTPase activity+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0042088///T-helper 1 type immune response+++GO:0043406///positive regulation of MAP kinase activity+++GO:0006897///endocytosis+++GO:0043547///positive regulation of GTPase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0010629///negative regulation of gene expression+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:2000630///positive regulation of miRNA metabolic process+++GO:0046330///positive regulation of JNK cascade+++GO:0008283///cell proliferation+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0006935///chemotaxis+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1900029///positive regulation of ruffle assembly+++GO:0007165///signal transduction+++GO:0000165///MAPK cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0090398///cellular senescence+++GO:0035900///response to isolation stress+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0010863///positive regulation of phospholipase C activity+++GO:0050852///T cell receptor signaling pathway+++GO:0042832///defense response to protozoan+++GO:0045740///positive regulation of DNA replication+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0007050///cell cycle arrest+++GO:0001934///positive regulation of protein phosphorylation+++GO:0043524///negative regulation of neuron apoptotic process","collagen alpha-2(IV) chain-like","[CO3A1_CHICK|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor; Fragments;+++[CO3A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(IV) chain; Contains: RecName: Full=Arresten; Flags: Precursor;+++[CO7A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(VII) chain; AltName: Full=Long-chain collagen; Short=LC collagen; Flags: Precursor;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[LRC56_HUMAN|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_MOUSE|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_RAT|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[PTSS2_CHICK|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_CRIGR|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_HUMAN|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_MOUSE|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_RAT|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[RASH_CHICK|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_HUMAN|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Ha-Ras; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_MOUSE|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_RAT|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASK_KRYMA|diamond]RecName: Full=GTPase KRas; AltName: Full=Ki-Ras; Short=K-ras; Flags: Precursor;+++[RASK_MONDO|diamond]RecName: Full=GTPase KRas; AltName: Full=K-Ras 2; AltName: Full=Ki-Ras; AltName: Full=c-K-ras; AltName: Full=c-Ki-ras; Contains: RecName: Full=GTPase KRas, N-terminally processed; Flags: Precursor;+++[RINI_HUMAN|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Placental ribonuclease inhibitor; Short=Placental RNase inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1; Short=RAI;+++[RINI_PANTR|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_PIG|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_RAT|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[101059915,"'LOC101059915'",0,0,1,0.333333333333333,{"$nulls":7},"chromosome X open reading frame 49-like","[A0A1B0GV59_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490381};+++[A0A1B0GWI6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000490941};"]
[101059918,"'GOLGA8R'",30.2,33.77,10.27,24.7466666666667,"04530///Tight junction",{"$nulls":3},"GO:0005794///Golgi apparatus",null,null,"golgin A8 family member R","[GOG8R_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 8R;"]
[101059938,"'NPIPA7'",979.58,1030.21,1285.34,1098.37666666667,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"nuclear pore complex interacting protein family member A7","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0Y2X3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A7 {ECO:0000313|Ensembl:ENSP00000343256}; Flags: Fragment;"]
[101059949,"'LOC101059949'",11.42,0,3.86,5.09333333333333,{"$nulls":7},"putative ankyrin repeat domain-containing protein 20A12 pseudogene","[A2012_HUMAN|diamond]RecName: Full=Putative ankyrin repeat domain-containing protein 20A12 pseudogene {ECO:0000305};+++[AN18A_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18A;+++[AN18B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18B;+++[ANR26_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000305};+++[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;"]
[101059953,"'NPIPA8'",189.34,156.36,195.24,180.313333333333,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"nuclear pore complex interacting protein family member A8","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0YFN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A8 {ECO:0000313|Ensembl:ENSP00000439498}; Flags: Fragment;"]
[10106,"'CTDSP2'",1542,1367,1267,1392,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0016791///phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0016311///dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle","CTD small phosphatase 2","[CTDS2_HUMAN|Reviewed]RecName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; EC=3.1.3.16; AltName: Full=Nuclear LIM interactor-interacting factor 2; Short=NLI-interacting factor 2; AltName: Full=Protein OS-4; AltName: Full=Small C-terminal domain phosphatase 2; AltName: Full=Small CTD phosphatase 2; Short=SCP2;+++[A0A024RB65_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_b {ECO:0000313|EMBL:EAW97086.1};+++[A0A024RBA6_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_c {ECO:0000313|EMBL:EAW97089.1};+++[F8VYL0_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448951};+++[F8W184_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000446705};+++[F8W1I1_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000447046};+++[H0YI12_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448299}; Flags: Fragment;+++[H0YI29_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448386}; Flags: Fragment;"]
[101060017,"'LOC101060017'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0032587///ruffle membrane+++GO:0005829///cytosol","GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0004672///protein kinase activity+++GO:0071889///14-3-3 protein binding+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0000165///MAPK cascade+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0043405///regulation of MAP kinase activity","translation initiation factor IF-2-like","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[KSR2_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 2; Short=hKSR2; EC=2.7.11.1;+++[KSR2_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 2; EC=2.7.11.1;"]
[101060022,"'LOC101060022'",412.37,469.66,475.46,452.496666666667,{"$nulls":7},"nascent polypeptide-associated complex subunit alpha, muscle-specific form-like","[PRR36_HUMAN|diamond]RecName: Full=Proline-rich protein 36 {ECO:0000312|HGNC:HGNC:26172};+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[101060024,"'LOC101060024'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane",null,null,"short transmembrane mitochondrial protein 1-like","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[STMP1_HUMAN|diamond]RecName: Full=Short transmembrane mitochondrial protein 1 {ECO:0000303|PubMed:23073385};+++[STMP1_MOUSE|diamond]RecName: Full=Short transmembrane mitochondrial protein 1 {ECO:0000250|UniProtKB:E0CX11};"]
[101060179,"'LOC101060179'",77,70,62,69.6666666666667,{"$nulls":7},"uncharacterized LOC101060179","[A0A2J8LHJ5_PANTR|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNI46744.1}; Flags: Fragment;+++[A0A2J8WFF8_PONAB|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNJ68516.1}; Flags: Fragment;+++[A0A2R8MD89_CALJA|diamond]SubName: Full=PR/SET domain 11 {ECO:0000313|Ensembl:ENSCJAP00000057788};+++[H3BSZ2_HUMAN|diamond]SubName: Full=PR domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000456942}; Flags: Fragment;+++[Q8N1K6_HUMAN|diamond]SubName: Full=cDNA FLJ40559 fis, clone THYMU2002910 {ECO:0000313|EMBL:BAC05192.1};"]
[101060200,"'ZNF891'",9,7,8,8,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 891","[ZN891_HUMAN|Reviewed]RecName: Full=Zinc finger protein 891;"]
[101060226,"'NBPF19'",1429.96,1163.61,1049.36,1214.31,"05224///Breast cancer+++01522///Endocrine resistance+++04137///Mitophagy - animal+++04330///Notch signaling pathway+++05200///Pathways in cancer+++04140///Autophagy - animal+++04320///Dorso-ventral axis formation+++04658///Th1 and Th2 cell differentiation+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection+++04919///Thyroid hormone signaling pathway","H00551///Alagille syndrome+++H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","NBPF member 19","[NBPFJ_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};+++[A0A075B6G5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000358229};+++[A0A087X230_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484655};+++[A0A087X288_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484787};"]
[101060254,"'LOC101060254'",70,53.09,35,52.6966666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0030016///myofibril","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization+++GO:1903358///regulation of Golgi organization+++GO:0034622///cellular protein-containing complex assembly","myomegalin-like","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_MOUSE|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[CK5P2_RAT|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFK_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 20;+++[NBPFP_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 26;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101060321,"'TBC1D3G'",47.39,55.28,26.17,42.9466666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","TBC1 domain family member 3G","[TBC3C_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3C;+++[TBC3G_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3G;"]
[101060341,"'LOC101060341'",360.88,393.07,347.48,367.143333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC101060341","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101060351,"'TBC1D3K'",13.84,0,19.6,11.1466666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","TBC1 domain family member 3K","[TBC3K_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3K {ECO:0000312|HGNC:HGNC:51245};+++[A0A0G2JPY0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3K {ECO:0000313|Ensembl:ENSP00000484542};"]
[101060376,"'TBC1D3L'",421.41,449.11,412.11,427.543333333333,{"$nulls":4},"GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0005622///intracellular","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0031338///regulation of vesicle fusion+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3L","[TBC3L_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3L {ECO:0000312|HGNC:HGNC:51246};+++[A0A0G2JP35_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3L {ECO:0000313|Ensembl:ENSP00000482811};+++[B3KTC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38066 fis, clone CTONG2015330, highly similar to TBC1 domain family member 3 {ECO:0000313|EMBL:BAG53037.1};"]
[101060389,"'TBC1D3D'",20.22,30.68,28.56,26.4866666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:1902017///regulation of cilium assembly+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3D","[TBC3D_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3D {ECO:0000312|HGNC:HGNC:28944};"]
[101060684,"'NBPF26'",556.36,513.23,411.49,493.693333333333,"04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++04140///Autophagy - animal+++05200///Pathways in cancer+++04137///Mitophagy - animal+++05165///Human papillomavirus infection+++04320///Dorso-ventral axis formation+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++01522///Endocrine resistance+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","NBPF member 26","[NBPFP_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 26;+++[A0A075B7F9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000476257};+++[A0A087WTG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000477847};+++[A0A087WU30_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000478334};+++[A0A087WVV8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000479721};+++[A0A087WWQ1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000480416};+++[A0A087WY62_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000481542};+++[A0A087WZB6_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482516};+++[A0A087WZS8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482859};+++[A0A096LNW5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000485259};"]
[10109,"'ARPC2'",4569,5649,5145,5121,"05132///Salmonella infection+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0005925///focal adhesion+++GO:0036195///muscle cell projection membrane+++GO:0035861///site of double-strand break+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031252///cell leading edge+++GO:0030027///lamellipodium+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0045202///synapse","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0070358///actin polymerization-dependent cell motility+++GO:0048013///ephrin receptor signaling pathway+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030041///actin filament polymerization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:0010592///positive regulation of lamellipodium assembly","actin related protein 2/3 complex subunit 2","[ARPC2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 2; AltName: Full=Arp2/3 complex 34 kDa subunit; Short=p34-ARC;+++[A0A024R408_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[C9JTV5_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[G5E9J0_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[G5E9S7_HUMAN|Unreviewed]SubName: Full=Actin related protein 2/3 complex, subunit 2, 34kDa, isoform CRA_e {ECO:0000313|EMBL:EAW70596.1}; SubName: Full=Actin-related protein 2/3 complex subunit 2 {ECO:0000313|Ensembl:ENSP00000412632};+++[H7C3F9_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[Q53R19_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};"]
[10110,"'SGK2'",9,1,5,5,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular","GO:0005524///ATP binding+++GO:0017081///chloride channel regulator activity+++GO:0005246///calcium channel regulator activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0015459///potassium channel regulator activity+++GO:0017080///sodium channel regulator activity","GO:0018105///peptidyl-serine phosphorylation+++GO:0034220///ion transmembrane transport+++GO:0001558///regulation of cell growth+++GO:0032411///positive regulation of transporter activity+++GO:0006468///protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0006979///response to oxidative stress+++GO:0042127///regulation of cell proliferation","SGK2, serine/threonine kinase 2","[SGK2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk2; EC=2.7.11.1; AltName: Full=Serum/glucocorticoid-regulated kinase 2;"]
[10111,"'RAD50'",1067,1002,802,957,"03450///Non-homologous end-joining+++04218///Cellular senescence+++03440///Homologous recombination","H01344///Nijmegen syndrome","M00292///MRX complex+++M00291///MRN complex+++M00295///BRCA1-associated genome surveillance complex (BASC)",null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000790///nuclear chromatin+++GO:0030870///Mre11 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0008408///3'-5' exonuclease activity+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003691///double-stranded telomeric DNA binding+++GO:0004017///adenylate kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding+++GO:0043047///single-stranded telomeric DNA binding","GO:0016032///viral process+++GO:0033674///positive regulation of kinase activity+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0032206///positive regulation of telomere maintenance+++GO:0000019///regulation of mitotic recombination+++GO:0016233///telomere capping+++GO:0000723///telomere maintenance+++GO:0000722///telomere maintenance via recombination+++GO:0000729///DNA double-strand break processing+++GO:0007004///telomere maintenance via telomerase+++GO:0031860///telomeric 3' overhang formation+++GO:0032508///DNA duplex unwinding+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0000724///double-strand break repair via homologous recombination+++GO:1904354///negative regulation of telomere capping+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0006260///DNA replication+++GO:0070192///chromosome organization involved in meiotic cell cycle","RAD50 double strand break repair protein","[RAD50_HUMAN|Reviewed]RecName: Full=DNA repair protein RAD50; Short=hRAD50; EC=3.6.-.-;+++[A5D6Y3_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI40006.1}; Flags: Fragment;+++[C9JNH8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000389515}; Flags: Fragment;+++[E7EN38_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000400049}; Flags: Fragment;+++[E7ESD9_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000390971};+++[E9PM98_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000431225};+++[H7C0P8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396100}; Flags: Fragment;+++[H7C0V2_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396860}; Flags: Fragment;+++[Q32P42_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI08283.1}; Flags: Fragment;"]
[10112,"'KIF20A'",0,4,1,1.66666666666667,{"$nulls":4},"GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005819///spindle+++GO:0045171///intercellular bridge+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005871///kinesin complex","GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0003777///microtubule motor activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0007018///microtubule-based movement+++GO:0032465///regulation of cytokinesis+++GO:0061952///midbody abscission+++GO:0000281///mitotic cytokinesis+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0001578///microtubule bundle formation","kinesin family member 20A","[KI20A_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF20A; AltName: Full=GG10_2; AltName: Full=Mitotic kinesin-like protein 2; Short=MKlp2; AltName: Full=Rab6-interacting kinesin-like protein; AltName: Full=Rabkinesin-6;+++[D6R9E4_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000422928}; Flags: Fragment;+++[D6RBN1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000424056}; Flags: Fragment;+++[H0YAC9_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000426704}; Flags: Fragment;"]
[10113,"'PREB'",1202,1327,1326,1285,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005090///Sar guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0051020///GTPase binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0048208///COPII vesicle coating+++GO:0003400///regulation of COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0050790///regulation of catalytic activity+++GO:0009306///protein secretion+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0016192///vesicle-mediated transport","prolactin regulatory element binding","[PREB_HUMAN|Reviewed]RecName: Full=Prolactin regulatory element-binding protein; AltName: Full=Mammalian guanine nucleotide exchange factor mSec12;+++[A0A0F7RPZ8_HUMAN|Unreviewed]SubName: Full=Prometheus B {ECO:0000313|EMBL:CCP37866.1};+++[B5MC98_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000384032};+++[F8WCS5_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000416103};+++[H7BZX0_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000391894}; Flags: Fragment;+++[H7C0W3_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000397036}; Flags: Fragment;+++[H7C2N7_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000407036}; Flags: Fragment;+++[Q05DB2_HUMAN|Unreviewed]SubName: Full=PREB protein {ECO:0000313|EMBL:AAH16906.1}; SubName: Full=Prolactin regulatory element binding, isoform CRA_d {ECO:0000313|EMBL:EAX00629.1};"]
[10114,"'HIPK3'",1323,1256,713,1097.33333333333,"04218///Cellular senescence",{"$nulls":3},"GO:0005829///cytosol+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0018107///peptidyl-threonine phosphorylation+++GO:0009299///mRNA transcription+++GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation","homeodomain interacting protein kinase 3","[HIPK3_HUMAN|Reviewed]RecName: Full=Homeodomain-interacting protein kinase 3; EC=2.7.11.1; AltName: Full=Androgen receptor-interacting nuclear protein kinase; Short=ANPK; AltName: Full=Fas-interacting serine/threonine-protein kinase; Short=FIST; AltName: Full=Homolog of protein kinase YAK1;+++[A8KAE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75520 {ECO:0000313|EMBL:BAF85698.1};+++[E9PKD7_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 3 {ECO:0000313|Ensembl:ENSP00000433594}; Flags: Fragment;"]
[10116,"'FEM1B'",508,471,291,423.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005123///death receptor binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:2000001///regulation of DNA damage checkpoint+++GO:0016567///protein ubiquitination+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0002070///epithelial cell maturation+++GO:0043687///post-translational protein modification+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0006915///apoptotic process","fem-1 homolog B","[FEM1B_HUMAN|Reviewed]RecName: Full=Protein fem-1 homolog B; Short=FEM1b; AltName: Full=FEM1-beta; AltName: Full=Fem-1-like death receptor-binding protein alpha; AltName: Full=Fem-1-like in apoptotic pathway protein alpha; Short=F1A-alpha;+++[H3BT12_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000456968}; Flags: Fragment;+++[H3BTV3_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000457342}; Flags: Fragment;"]
[1012,"'CDH13'",172,164,116,150.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016342///catenin complex+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0009986///cell surface+++GO:0048471///perinuclear region of cytoplasm+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0098982///GABA-ergic synapse+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0055100///adiponectin binding+++GO:0071813///lipoprotein particle binding+++GO:0008092///cytoskeletal protein binding+++GO:0045296///cadherin binding+++GO:0030169///low-density lipoprotein particle binding","GO:0010033///response to organic substance+++GO:0007266///Rho protein signal transduction+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0034332///adherens junction organization+++GO:0030335///positive regulation of cell migration+++GO:0043542///endothelial cell migration+++GO:0043616///keratinocyte proliferation+++GO:0016601///Rac protein signal transduction+++GO:0050927///positive regulation of positive chemotaxis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0007043///cell-cell junction assembly+++GO:0030032///lamellipodium assembly+++GO:0030100///regulation of endocytosis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0002040///sprouting angiogenesis+++GO:0007155///cell adhesion+++GO:0000278///mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051668///localization within membrane","cadherin 13","[CAD13_HUMAN|Reviewed]RecName: Full=Cadherin-13; AltName: Full=Heart cadherin; Short=H-cadherin; AltName: Full=P105; AltName: Full=Truncated cadherin; Short=T-cad; Short=T-cadherin; Flags: Precursor;+++[B7Z3H7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50547, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH12213.1};+++[B7Z9B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52398, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH14247.1};+++[F5H7W7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000442225};+++[H3BQH4_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000455781};+++[H3BRL7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000456297};+++[H3BTF2_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457149};+++[H3BV21_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457914};"]
[10120,"'ACTR1B'",674,597,712,661,{"$nulls":4},"GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0034774///secretory granule lumen+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0005869///dynactin complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0015630///microtubule cytoskeleton+++GO:0005856///cytoskeleton","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","ARP1 actin related protein 1 homolog B","[ACTY_HUMAN|Reviewed]RecName: Full=Beta-centractin; AltName: Full=Actin-related protein 1B; Short=ARP1B;"]
[10121,"'ACTR1A'",2851,3129,3397,3125.66666666667,{"$nulls":4},"GO:0005869///dynactin complex+++GO:0043209///myelin sheath+++GO:0005829///cytosol+++GO:0099738///cell cortex region+++GO:0030137///COPI-coated vesicle+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0002177///manchette+++GO:0015630///microtubule cytoskeleton+++GO:0005814///centriole+++GO:0070062///extracellular exosome+++GO:0005875///microtubule associated complex+++GO:0005815///microtubule organizing center+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0016192///vesicle-mediated transport+++GO:0007283///spermatogenesis+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport","ARP1 actin related protein 1 homolog A","[ACTZ_HUMAN|Reviewed]RecName: Full=Alpha-centractin; Short=Centractin; AltName: Full=ARP1; AltName: Full=Actin-RPV; AltName: Full=Centrosome-associated actin homolog;+++[A0A1B0GVS3_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000490634};+++[R4GMT0_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000473334};"]
[10123,"'ARL4C'",1316,1630,1442,1462.66666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding+++GO:0005525///GTP binding","GO:0032456///endocytic recycling+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","ADP ribosylation factor like GTPase 4C","[ARL4C_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4C; AltName: Full=ADP-ribosylation factor-like protein 7; AltName: Full=ADP-ribosylation factor-like protein LAK;+++[A0A024R4C5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4C, isoform CRA_a {ECO:0000313|EMBL:EAW71074.1};"]
[10124,"'ARL4A'",206,290,263.94,253.313333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","ADP ribosylation factor like GTPase 4A","[ARL4A_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4A;+++[A0A024R9Z2_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4A, isoform CRA_a {ECO:0000313|EMBL:EAW93652.1};+++[C9J7Q9_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 4A {ECO:0000313|Ensembl:ENSP00000397651}; Flags: Fragment;"]
[10125,"'RASGRP1'",118,113,74,101.666666666667,"05200///Pathways in cancer+++04660///T cell receptor signaling pathway+++04611///Platelet activation+++04014///Ras signaling pathway+++04010///MAPK signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0042629///mast cell granule+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0019992///diacylglycerol binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005096///GTPase activator activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031210///phosphatidylcholine binding+++GO:0042803///protein homodimerization activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1900744///regulation of p38MAPK cascade+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007264///small GTPase mediated signal transduction+++GO:1902715///positive regulation of interferon-gamma secretion+++GO:0090630///activation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0007165///signal transduction+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001816///cytokine production+++GO:0043303///mast cell degranulation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0047496///vesicle transport along microtubule+++GO:0043087///regulation of GTPase activity+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0007265///Ras protein signal transduction+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0000165///MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0032252///secretory granule localization+++GO:1900274///regulation of phospholipase C activity+++GO:0030154///cell differentiation+++GO:0032816///positive regulation of natural killer cell activation","RAS guanyl releasing protein 1","[GRP1_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 1; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor II; Short=CalDAG-GEFII; AltName: Full=Ras guanyl-releasing protein;+++[B2RA89_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94771, highly similar to Homo sapiens RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), mRNA {ECO:0000313|EMBL:BAG36786.1};+++[F5H514_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000444762};+++[H0YKM0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452859};+++[H0YKP8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452892}; Flags: Fragment;+++[H0YMF3_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453583}; Flags: Fragment;+++[H0YMT0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453729}; Flags: Fragment;+++[H0YN83_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453905}; Flags: Fragment;+++[H0YNG8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454005}; Flags: Fragment;+++[H0YNK9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454053}; Flags: Fragment;"]
[10126,"'DNAL4'",219,253,275,249,"05016///Huntington's disease",{"$nulls":3},"GO:0005874///microtubule+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0030286///dynein complex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005929///cilium","GO:0051959///dynein light intermediate chain binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0005515///protein binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0045505///dynein intermediate chain binding","GO:0007018///microtubule-based movement+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed+++GO:0007017///microtubule-based process","dynein axonemal light chain 4","[DNAL4_HUMAN|Reviewed]RecName: Full=Dynein light chain 4, axonemal;+++[B0QXZ5_HUMAN|Unreviewed]RecName: Full=Dynein light chain {ECO:0000256|RuleBase:RU365010};"]
[10127,"'ZNF263'",411,402,355,389.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","zinc finger protein 263","[ZN263_HUMAN|Reviewed]RecName: Full=Zinc finger protein 263; AltName: Full=Zinc finger protein FPM315; AltName: Full=Zinc finger protein with KRAB and SCAN domains 12;+++[B4DI05_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57935, highly similar to Zinc finger protein 263 {ECO:0000313|EMBL:BAG58317.1};+++[D3DUC1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263, isoform CRA_a {ECO:0000313|EMBL:EAW85380.1};+++[I3L0N0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000458214}; Flags: Fragment;+++[I3L2X3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000459998};+++[I3L393_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000460278};+++[I3L4C4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461146}; Flags: Fragment;+++[I3L538_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461755}; Flags: Fragment;+++[I3NI39_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461861}; Flags: Fragment;"]
[10128,"'LRPPRC'",1260,1326,1146,1244,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01354///Leigh syndrome+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0000794///condensed nuclear chromosome+++GO:1990904///ribonucleoprotein complex+++GO:0005874///microtubule+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005640///nuclear outer membrane+++GO:0005634///nucleus+++GO:0042645///mitochondrial nucleoid+++GO:0005637///nuclear inner membrane+++GO:0005856///cytoskeleton","GO:0008017///microtubule binding+++GO:0048487///beta-tubulin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0051015///actin filament binding+++GO:0003697///single-stranded DNA binding","GO:0070129///regulation of mitochondrial translation+++GO:0051028///mRNA transport+++GO:0000961///negative regulation of mitochondrial RNA catabolic process+++GO:0047497///mitochondrion transport along microtubule","leucine rich pentatricopeptide repeat containing","[LPPRC_HUMAN|Reviewed]RecName: Full=Leucine-rich PPR motif-containing protein, mitochondrial; AltName: Full=130 kDa leucine-rich protein; Short=LRP 130; AltName: Full=GP130; Flags: Precursor;+++[A0A0C4DG06_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386234};+++[B8ZZ38_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386562};+++[C9JCA9_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000403637}; Flags: Fragment;+++[E5KNY5_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR-motif containing {ECO:0000313|EMBL:EAX00284.1}; SubName: Full=Mitochondrial leucine-rich PPR motif-containing protein {ECO:0000313|EMBL:ADP90894.1};+++[H7C3W8_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000414207}; Flags: Fragment;"]
[10129,"'FRY'",235,194,132,187,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0004857///enzyme inhibitor activity","GO:0000902///cell morphogenesis+++GO:0043086///negative regulation of catalytic activity+++GO:0031175///neuron projection development+++GO:1904428///negative regulation of tubulin deacetylation","FRY microtubule binding protein","[FRY_HUMAN|Reviewed]RecName: Full=Protein furry homolog;+++[A0A024RDQ1_HUMAN|Unreviewed]SubName: Full=Furry homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAX08493.1};+++[A0A0C4DFX2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000369600};+++[A0A286YFA9_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000493189};+++[A0A2R8Y5V8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494761};+++[A0A2R8Y7Y8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000496501}; Flags: Fragment;+++[A0A2R8YCY2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494080};+++[B1ALA1_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000398010}; Flags: Fragment;+++[H0YE00_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000434694}; Flags: Fragment;+++[L8EB55_HUMAN|Unreviewed]SubName: Full=Alternative protein FRY {ECO:0000313|EMBL:CCQ43703.1};+++[Q96KW3_HUMAN|Unreviewed]SubName: Full=214K23.2.1 (Novel protein, isoform 1) {ECO:0000313|EMBL:CAC94765.1}; Flags: Fragment;+++[Q96KW4_HUMAN|Unreviewed]SubName: Full=214K23.2.2 (Novel protein, isoform 2) {ECO:0000313|EMBL:CAC94764.1}; Flags: Fragment;"]
[1013,"'CDH15'",14,13,21,16,"04514///Cell adhesion molecules (CAMs)","H00773///Autosomal dominant mental retardation",null,null,"GO:0005901///caveola+++GO:0031594///neuromuscular junction+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0016342///catenin complex","GO:0008092///cytoskeletal protein binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0003674///molecular_function+++GO:0042803///protein homodimerization activity","GO:0042060///wound healing+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:1902910///positive regulation of melanosome transport+++GO:0050896///response to stimulus+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0022405///hair cycle process+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0042493///response to drug+++GO:0007155///cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0007601///visual perception+++GO:0031424///keratinization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051796///negative regulation of timing of catagen+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0007043///cell-cell junction assembly+++GO:0001895///retina homeostasis+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation","cadherin 15","[CAD15_HUMAN|Reviewed]RecName: Full=Cadherin-15; AltName: Full=Cadherin-14; AltName: Full=Muscle cadherin; Short=M-cadherin; Flags: Precursor;+++[J3KRQ1_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000462111}; Flags: Fragment;+++[J3QKW6_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463267}; Flags: Fragment;+++[J3QL41_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463364}; Flags: Fragment;+++[J3QL75_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463415}; Flags: Fragment;+++[J3QR34_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464021};+++[J3QR60_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464058}; Flags: Fragment;"]
[10130,"'PDIA6'",6441,7138,6794,6791,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0042470///melanosome+++GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0003756///protein disulfide isomerase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0006457///protein folding+++GO:0044267///cellular protein metabolic process+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process","protein disulfide isomerase family A member 6","[PDIA6_HUMAN|Reviewed]RecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1 {ECO:0000269|PubMed:12204115, ECO:0000269|PubMed:15466936}; AltName: Full=Endoplasmic reticulum protein 5; Short=ER protein 5; Short=ERp5; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor;+++[C9JNG5_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A6 {ECO:0000313|Ensembl:ENSP00000389558}; Flags: Fragment;"]
[10131,"'TRAP1'",1381,1420,1562,1454.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005759///mitochondrial matrix","GO:0051082///unfolded protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003723///RNA binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0061077///chaperone-mediated protein folding+++GO:0009386///translational attenuation+++GO:1901856///negative regulation of cellular respiration+++GO:0006950///response to stress+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process","TNF receptor associated protein 1","[TRAP1_HUMAN|Reviewed]RecName: Full=Heat shock protein 75 kDa, mitochondrial; Short=HSP 75; AltName: Full=TNFR-associated protein 1; AltName: Full=Tumor necrosis factor type 1 receptor-associated protein; Short=TRAP-1; Flags: Precursor;+++[A0A140VJY2_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 209 {ECO:0000313|EMBL:AEE61119.1};+++[I3L0K7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458166}; SubName: Full=TNF receptor-associated protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW85339.1};+++[I3L0P6_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458244}; Flags: Fragment;+++[I3L239_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459354}; Flags: Fragment;+++[I3L253_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459385}; Flags: Fragment;+++[I3L2D5_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459585}; Flags: Fragment;+++[I3L3L4_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000460545};+++[I3L4L7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000461354};+++[K0A7K7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:AFS69159.1}; Flags: Fragment;+++[Q53FS6_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 variant {ECO:0000313|EMBL:BAD96925.1}; Flags: Fragment;+++[Q5CAQ4_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:CAI64498.1}; SubName: Full=cDNA FLJ33058 fis, clone TRACH1000181, highly similar to Heat shock protein 75 kDa, mitochondrial {ECO:0000313|EMBL:BAG51942.1};+++[Q9BV61_HUMAN|Unreviewed]SubName: Full=TRAP1 protein {ECO:0000313|EMBL:AAH01455.2}; Flags: Fragment;"]
[10133,"'OPTN'",1711,1944,1693,1782.66666666667,"04137///Mitophagy - animal","H00612///Primary open angle glaucoma+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0055037///recycling endosome+++GO:0005802///trans-Golgi network+++GO:0005776///autophagosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005634///nucleus","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0030674///protein binding, bridging+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding","GO:0045087///innate immune response+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016192///vesicle-mediated transport+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007030///Golgi organization+++GO:0090161///Golgi ribbon formation+++GO:1904417///positive regulation of xenophagy+++GO:0006914///autophagy+++GO:0001920///negative regulation of receptor recycling+++GO:0008219///cell death+++GO:0034067///protein localization to Golgi apparatus+++GO:0034620///cellular response to unfolded protein+++GO:0002376///immune system process+++GO:0050829///defense response to Gram-negative bacterium+++GO:0034613///cellular protein localization+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0010508///positive regulation of autophagy+++GO:0007165///signal transduction","optineurin","[OPTN_HUMAN|Reviewed]RecName: Full=Optineurin; AltName: Full=E3-14.7K-interacting protein; AltName: Full=FIP-2; AltName: Full=Huntingtin yeast partner L; AltName: Full=Huntingtin-interacting protein 7; Short=HIP-7; AltName: Full=Huntingtin-interacting protein L; AltName: Full=NEMO-related protein; AltName: Full=Optic neuropathy-inducing protein; AltName: Full=Transcription factor IIIA-interacting protein; Short=TFIIIA-IntP;+++[A0A087WY28_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000481473}; Flags: Fragment;+++[A0A087X2G2_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000484961};+++[A0A0S2Z500_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 1 {ECO:0000313|EMBL:ALQ33960.1}; Flags: Fragment;+++[A0A0S2Z5I6_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 3 {ECO:0000313|EMBL:ALQ33961.1};+++[H7C1H4_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000400356}; Flags: Fragment;+++[X6RKL2_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 4 {ECO:0000313|EMBL:ALQ33962.1};"]
[10134,"'BCAP31'",2226,2996,3264,2828.66666666667,"05165///Human papillomavirus infection+++04141///Protein processing in endoplasmic reticulum","H00849///Creatine deficiency syndrome+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0030136///clathrin-coated vesicle+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0032580///Golgi cisterna membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0005784///Sec61 translocon complex+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005811///lipid droplet+++GO:0005887///integral component of plasma membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0042288///MHC class I protein binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0015031///protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007283///spermatogenesis+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0006886///intracellular protein transport+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:0016192///vesicle-mediated transport+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0006915///apoptotic process","B cell receptor associated protein 31","[BAP31_HUMAN|Reviewed]RecName: Full=B-cell receptor-associated protein 31; Short=BCR-associated protein 31; Short=Bap31; AltName: Full=6C6-AG tumor-associated antigen; AltName: Full=Protein CDM; AltName: Full=p28;+++[A0A2R8Y5M6_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000494936};+++[C9J0M4_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000400345}; Flags: Fragment;+++[C9JM14_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000402342}; Flags: Fragment;+++[C9JMD7_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000389740}; Flags: Fragment;+++[C9JQ75_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000409888}; Flags: Fragment;+++[C9JSP1_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000394270}; Flags: Fragment;"]
[10135,"'NAMPT'",465,451,601,505.666666666667,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways+++04621///NOD-like receptor signaling pathway",null,null,"R01271///nicotinamide-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase   Nicotinamide D-ribonucleotide + Diphosphate <=> Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate","GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0005615///extracellular space","GO:0042803///protein homodimerization activity+++GO:0008144///drug binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047280///nicotinamide phosphoribosyltransferase activity+++GO:0042802///identical protein binding+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0005125///cytokine activity","GO:0014070///response to organic cyclic compound+++GO:0009435///NAD biosynthetic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0060612///adipose tissue development+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0001774///microglial cell activation+++GO:0008284///positive regulation of cell proliferation+++GO:1905377///response to D-galactose+++GO:0070997///neuron death+++GO:0032922///circadian regulation of gene expression+++GO:0007568///aging+++GO:0010469///regulation of signaling receptor activity+++GO:1904646///cellular response to amyloid-beta+++GO:0007565///female pregnancy+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0010507///negative regulation of autophagy+++GO:0007267///cell-cell signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0007623///circadian rhythm+++GO:0048511///rhythmic process+++GO:0034356///NAD biosynthesis via nicotinamide riboside salvage pathway+++GO:0014916///regulation of lung blood pressure","nicotinamide phosphoribosyltransferase","[NAMPT_HUMAN|Reviewed]RecName: Full=Nicotinamide phosphoribosyltransferase; Short=NAmPRTase; Short=Nampt; EC=2.4.2.12; AltName: Full=Pre-B-cell colony-enhancing factor 1; Short=Pre-B cell-enhancing factor; AltName: Full=Visfatin;+++[A0A024R718_HUMAN|Unreviewed]SubName: Full=Pre-B-cell colony enhancing factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW83384.1};+++[A0A0C4DFS8_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000346242};+++[C9JF35_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390896}; Flags: Fragment;+++[C9JG65_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390591}; Flags: Fragment;"]
[10137,"'RBM12'",1387.86,1242,1072.71,1234.19,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding",null,"RNA binding motif protein 12","[RBM12_HUMAN|Reviewed]RecName: Full=RNA-binding protein 12; AltName: Full=RNA-binding motif protein 12; AltName: Full=SH3/WW domain anchor protein in the nucleus; Short=SWAN;+++[A6PVI0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000392642}; Flags: Fragment;+++[A6PVI1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411692}; Flags: Fragment;+++[Q5JX62_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411036}; Flags: Fragment;"]
[10138,"'YAF2'",167,170,118,151.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity","GO:0070317///negative regulation of G0 to G1 transition+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","YY1 associated factor 2","[YAF2_HUMAN|Reviewed]RecName: Full=YY1-associated factor 2;+++[A0A0B4J255_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447863};+++[B4DJQ9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57510, highly similar to YY1-associated factor 2 {ECO:0000313|EMBL:BAG58921.1};+++[F8VRE5_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448533};+++[F8VZR2_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447686}; Flags: Fragment;+++[F8W0B9_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447217};+++[G3V1X5_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_g {ECO:0000313|EMBL:EAW57840.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448291};+++[G3V212_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_b {ECO:0000313|EMBL:EAW57835.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450097};+++[G3V219_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_d {ECO:0000313|EMBL:EAW57837.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450394};"]
[10139,"'ARFRP1'",286,278,378,314,"04060///Cytokine-cytokine receptor interaction","H00108///Autoimmune lymphoproliferative syndromes (ALPS)",null,null,"GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032588///trans-Golgi network membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:0007369///gastrulation+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007165///signal transduction+++GO:0033365///protein localization to organelle+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0034067///protein localization to Golgi apparatus+++GO:0006886///intracellular protein transport","ADP ribosylation factor related protein 1","[ARFRP_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-related protein 1; Short=ARF-related protein 1; Short=ARP;+++[B7ZKY8_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1 {ECO:0000313|EMBL:AAI43468.1};+++[H0UI96_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW75236.1};"]
[1014,"'CDH16'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0007267///cell-cell signaling+++GO:0007399///nervous system development","cadherin 16","[CAD16_HUMAN|Reviewed]RecName: Full=Cadherin-16; AltName: Full=Kidney-specific cadherin; Short=Ksp-cadherin; Flags: Precursor;"]
[10140,"'TOB1'",1412,1266,864,1180.66666666667,"03018///RNA degradation",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex","GO:0005515///protein binding+++GO:0046332///SMAD binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0003714///transcription corepressor activity+++GO:0030971///receptor tyrosine kinase binding","GO:0060212///negative regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0009967///positive regulation of signal transduction+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0017148///negative regulation of translation+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0008285///negative regulation of cell proliferation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0010468///regulation of gene expression+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening","transducer of ERBB2, 1","[TOB1_HUMAN|Reviewed]RecName: Full=Protein Tob1; AltName: Full=Transducer of erbB-2 1;"]
[101410538,"'MMP24OS'",4644,5585,5633,5287.33333333333,{"$nulls":7},"MMP24 opposite strand","[MMPOS_HUMAN|Reviewed]RecName: Full=Protein MMP24OS {ECO:0000305}; AltName: Full=MMP24 opposite strand {ECO:0000312|HGNC:HGNC:44421};"]
[10142,"'AKAP9'",1363,1450,996,1269.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00720///Long QT syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0099147///extrinsic component of postsynaptic density membrane+++GO:0043025///neuronal cell body+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0044307///dendritic branch+++GO:0005795///Golgi stack+++GO:0097060///synaptic membrane+++GO:0005815///microtubule organizing center+++GO:0005801///cis-Golgi network+++GO:0008076///voltage-gated potassium channel complex+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0005813///centrosome","GO:0015459///potassium channel regulator activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0016301///kinase activity+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0034237///protein kinase A regulatory subunit binding","GO:0051602///response to electrical stimulus+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0007165///signal transduction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0016310///phosphorylation+++GO:1903358///regulation of Golgi organization+++GO:0071320///cellular response to cAMP+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0060306///regulation of membrane repolarization+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:0007268///chemical synaptic transmission+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0051661///maintenance of centrosome location+++GO:0031116///positive regulation of microtubule polymerization+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007020///microtubule nucleation+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0000086///G2/M transition of mitotic cell cycle","A-kinase anchoring protein 9","[AKAP9_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 9; Short=AKAP-9; AltName: Full=A-kinase anchor protein 350 kDa; Short=AKAP 350; Short=hgAKAP 350; AltName: Full=A-kinase anchor protein 450 kDa; Short=AKAP 450; AltName: Full=AKAP 120-like protein; AltName: Full=Centrosome- and Golgi-localized PKN-associated protein {ECO:0000303|PubMed:10358086}; Short=CG-NAP {ECO:0000303|PubMed:10358086}; AltName: Full=Protein hyperion {ECO:0000303|Ref.4}; AltName: Full=Protein kinase A-anchoring protein 9; Short=PRKA9; AltName: Full=Protein yotiao {ECO:0000303|PubMed:9482789};+++[A0A087WX84_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000480807};+++[A0A0A0MRE9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000350813};+++[A0A0A0MRF6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000351922};+++[A0A2R8Y590_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000494626}; Flags: Fragment;+++[A4D1E4_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9 {ECO:0000313|EMBL:EAL24158.1};+++[H0Y6Q0_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000406937}; Flags: Fragment;+++[H7BYL6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378042}; Flags: Fragment;+++[H7BZV6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000391704}; Flags: Fragment;+++[Q5GIA7_HUMAN|Unreviewed]SubName: Full=Antigen MU-RMS-40.16A {ECO:0000313|EMBL:AAT44400.1}; Flags: Fragment;+++[Q6PJH3_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9, isoform CRA_c {ECO:0000313|EMBL:EAW76862.1}; SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378065}; SubName: Full=AKAP9 protein {ECO:0000313|EMBL:AAH15533.1};"]
[10144,"'FAM13A'",2399,1427,1439,1755,"04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","family with sequence similarity 13 member A","[FA13A_HUMAN|Reviewed]RecName: Full=Protein FAM13A;+++[A0A2X0SFT1_HUMAN|Unreviewed]SubName: Full=FAM13A {ECO:0000313|EMBL:SPT35754.1}; Flags: Fragment;+++[D6RCC1_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000423800};+++[D6RD35_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000427077};+++[D6RFM4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000426517};+++[D6RGE4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421269}; Flags: Fragment;+++[D6RIY4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000425784};+++[E9PGM7_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421914};+++[L0R4X6_HUMAN|Unreviewed]SubName: Full=Alternative protein FAM13A {ECO:0000313|EMBL:CCO13728.1};+++[Q6P521_HUMAN|Unreviewed]SubName: Full=FAM13A protein {ECO:0000313|EMBL:AAH63126.1}; SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000422345};"]
[10146,"'G3BP1'",944,1043,807,931.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0043204///perikaryon+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0010494///cytoplasmic stress granule","GO:0004518///nuclease activity+++GO:0003676///nucleic acid binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0004519///endonuclease activity+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0003729///mRNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding","GO:0034063///stress granule assembly+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0032508///DNA duplex unwinding+++GO:0007265///Ras protein signal transduction","G3BP stress granule assembly factor 1","[G3BP1_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12 {ECO:0000269|PubMed:9889278}; EC=3.6.4.13 {ECO:0000269|PubMed:9889278}; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1;+++[E5RH00_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430045};+++[E5RH42_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429920}; Flags: Fragment;+++[E5RI46_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000428469}; Flags: Fragment;+++[E5RIF8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430738}; Flags: Fragment;+++[E5RIZ6_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429250}; Flags: Fragment;+++[E5RJU8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430480};+++[Q32P45_HUMAN|Unreviewed]SubName: Full=GTPase activating protein (SH3 domain) binding protein 1 {ECO:0000313|EMBL:AAI08279.1};+++[Q5U0Q1_HUMAN|Unreviewed]SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein {ECO:0000313|EMBL:AAV38191.1}; SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW61659.1}; SubName: Full=cDNA, FLJ92947, Homo sapiens Ras-GTPase-activating protein SH3-domain-bindingprotein (G3BP), mRNA {ECO:0000313|EMBL:BAG35467.1};+++[Q6FI03_HUMAN|Unreviewed]SubName: Full=G3BP protein {ECO:0000313|EMBL:CAG38772.1};+++[Q6ZP53_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1 {ECO:0000313|EMBL:BAC85272.1};"]
[10147,"'SUGP2'",2171.75,1997.01,1811,1993.25333333333,{"$nulls":4},"GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0006396///RNA processing+++GO:0008380///RNA splicing","SURP and G-patch domain containing 2","[SUGP2_HUMAN|Reviewed]RecName: Full=SURP and G-patch domain-containing protein 2; AltName: Full=Arginine/serine-rich-splicing factor 14; AltName: Full=Splicing factor, arginine/serine-rich 14;+++[A0A024R7K0_HUMAN|Unreviewed]SubName: Full=Splicing factor, arginine/serine-rich 14, isoform CRA_a {ECO:0000313|EMBL:EAW84768.1};+++[A8K5G0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76836, highly similar to Homo sapiens splicing factor, arginine/serine-rich 14 (SFRS14), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83964.1};+++[M0R065_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000471042}; Flags: Fragment;+++[M0R1Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472183}; Flags: Fragment;+++[M0R216_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472244}; Flags: Fragment;+++[M0R2Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472878}; Flags: Fragment;+++[M0R2Z9_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472914};+++[M0R3F6_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000473187};"]
[10148,"'EBI3'",20,32,36,29.3333333333333,{"$nulls":4},"GO:0070110///ciliary neurotrophic factor receptor complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043235///receptor complex+++GO:0097059///CNTFR-CLCF1 complex","GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0045523///interleukin-27 receptor binding+++GO:0019955///cytokine binding","GO:0006959///humoral immune response+++GO:0042088///T-helper 1 type immune response+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0070757///interleukin-35-mediated signaling pathway+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0042098///T cell proliferation","Epstein-Barr virus induced 3","[IL27B_HUMAN|Reviewed]RecName: Full=Interleukin-27 subunit beta; Short=IL-27 subunit beta; Short=IL-27B; AltName: Full=Epstein-Barr virus-induced gene 3 protein; Short=EBV-induced gene 3 protein; Flags: Precursor;"]
[10149,"'ADGRG2'",7,6,15,9.33333333333333,null,"H01033///Congenital bilateral absence of vas deferens",null,null,"GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome","GO:0004930///G protein-coupled receptor activity+++GO:0004888///transmembrane signaling receptor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007166///cell surface receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor G2","[AGRG2_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor G2 {ECO:0000303|PubMed:25713288}; AltName: Full=G-protein coupled receptor 64; AltName: Full=Human epididymis-specific protein 6; Short=He6; Flags: Precursor;+++[A0A024RC03_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64, isoform CRA_a {ECO:0000313|EMBL:EAW98954.1};+++[A8K4P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77493, highly similar to Homo sapiens G protein-coupled receptor 64 (GPR64), mRNA {ECO:0000313|EMBL:BAF83701.1};+++[Q14CE1_HUMAN|Unreviewed]SubName: Full=GPR64 protein {ECO:0000313|EMBL:AAI13979.1};+++[Q499H0_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64 {ECO:0000313|EMBL:AAH99901.1};"]
[1015,"'CDH17'",3,0,0,1,"05226///Gastric cancer",{"$nulls":3},"GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0005913///cell-cell adherens junction+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0005178///integrin binding+++GO:0046872///metal ion binding+++GO:0005215///transporter activity+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0005427///proton-dependent oligopeptide secondary active transmembrane transporter activity+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding","GO:0048536///spleen development+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0035672///oligopeptide transmembrane transport+++GO:0033626///positive regulation of integrin activation by cell surface receptor linked signal transduction+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007229///integrin-mediated signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0007155///cell adhesion+++GO:0030183///B cell differentiation+++GO:0034332///adherens junction organization+++GO:0007043///cell-cell junction assembly+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0002314///germinal center B cell differentiation+++GO:0006857///oligopeptide transport+++GO:0002315///marginal zone B cell differentiation","cadherin 17","[CAD17_HUMAN|Reviewed]RecName: Full=Cadherin-17; AltName: Full=Intestinal peptide-associated transporter HPT-1; AltName: Full=Liver-intestine cadherin; Short=LI-cadherin; Flags: Precursor;+++[A0A0B4J288_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000455523};+++[E5RJT3_HUMAN|Unreviewed]SubName: Full=Cadherin-17 {ECO:0000313|Ensembl:ENSP00000428189}; Flags: Fragment;+++[E7EN24_HUMAN|Unreviewed]SubName: Full=Cadherin-17 {ECO:0000313|Ensembl:ENSP00000392811};+++[H0YBL0_HUMAN|Unreviewed]SubName: Full=Cadherin-17 {ECO:0000313|Ensembl:ENSP00000429730}; Flags: Fragment;+++[H3BSG2_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000456690};+++[H3BSV3_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000456891};+++[I3L418_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000460891}; Flags: Fragment;+++[J3QLA1_HUMAN|Unreviewed]SubName: Full=Cadherin-16 {ECO:0000313|Ensembl:ENSP00000463451}; Flags: Fragment;"]
[10150,"'MBNL2'",2530,3143,2053,2575.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","muscleblind like splicing regulator 2","[MBNL2_HUMAN|Reviewed]RecName: Full=Muscleblind-like protein 2; AltName: Full=Muscleblind-like protein 1; AltName: Full=Muscleblind-like protein-like; AltName: Full=Muscleblind-like protein-like 39;+++[A0PJJ3_HUMAN|Unreviewed]SubName: Full=MBNL2 protein {ECO:0000313|EMBL:AAH32426.1}; Flags: Fragment;+++[A2A3S3_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAX08968.1}; SubName: Full=cDNA FLJ76890, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF84416.1}; SubName: Full=cDNA, FLJ79493, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF98735.1};+++[O95205_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAX08969.1}; SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000432422}; SubName: Full=Zinc finger protein {ECO:0000313|EMBL:AAC67242.1};+++[Q5JSC0_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000404202}; Flags: Fragment;"]
[10152,"'ABI2'",1477.92,1281.02,1066.82,1275.25333333333,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0032433///filopodium tip+++GO:0030054///cell junction+++GO:0031209///SCAR complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030175///filopodium+++GO:0005634///nucleus+++GO:0005912///adherens junction","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0017124///SH3 domain binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0048365///Rac GTPase binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0003674///molecular_function+++GO:0070064///proline-rich region binding","GO:0016032///viral process+++GO:0007399///nervous system development+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation+++GO:0008150///biological_process+++GO:0008154///actin polymerization or depolymerization+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0016601///Rac protein signal transduction+++GO:0007010///cytoskeleton organization","abl interactor 2","[ABI2_HUMAN|Reviewed]RecName: Full=Abl interactor 2 {ECO:0000303|Ref.16}; AltName: Full=Abelson interactor 2 {ECO:0000303|Ref.16}; Short=Abi-2 {ECO:0000303|PubMed:7590236}; AltName: Full=Abl-binding protein 3; Short=AblBP3; AltName: Full=Arg-binding protein 1 {ECO:0000303|PubMed:8649853}; Short=ArgBP1 {ECO:0000303|PubMed:8649853};+++[A0A0C4DG21_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000391433};+++[B7Z836_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51162, highly similar to Abl interactor 2 {ECO:0000313|EMBL:BAH13822.1};+++[E7EP65_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000414703}; Flags: Fragment;+++[E7EUA1_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000398487};+++[E7EW77_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000396249};+++[E9PEZ7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408898};+++[F8WAL6_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000261018};+++[F8WAQ3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000410509}; Flags: Fragment;+++[F8WAU3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405255};+++[F8WAZ8_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000397850};+++[F8WBL5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405801};+++[F8WCD7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000399040};+++[F8WEB9_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408334};+++[H0Y6B5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000404352}; Flags: Fragment;+++[H7C3Q7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000413375}; Flags: Fragment;+++[Q13802_HUMAN|Unreviewed]SubName: Full=ArgBPIB protein {ECO:0000313|EMBL:CAA64980.1};+++[Q53RS4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14935.1}; Flags: Fragment;+++[Q53SH3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14675.1}; Flags: Fragment;"]
[10153,"'CEBPZ'",369,315,291,325,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","CCAAT enhancer binding protein zeta","[CEBPZ_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein zeta; AltName: Full=CCAAT-box-binding transcription factor; Short=CBF; Short=CCAAT-binding factor;+++[C9J9W7_HUMAN|Unreviewed]SubName: Full=CCAAT/enhancer-binding protein zeta {ECO:0000313|Ensembl:ENSP00000391881}; Flags: Fragment;"]
[10154,"'PLXNC1'",12,15,28,18.3333333333333,"04360///Axon guidance","H00537///Nephronophthisis",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0002116///semaphorin receptor complex","GO:0017154///semaphorin receptor activity+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0007162///negative regulation of cell adhesion+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:0008360///regulation of cell shape+++GO:0030334///regulation of cell migration+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007165///signal transduction+++GO:0050772///positive regulation of axonogenesis+++GO:0043087///regulation of GTPase activity+++GO:0007155///cell adhesion","plexin C1","[PLXC1_HUMAN|Reviewed]RecName: Full=Plexin-C1; AltName: Full=Virus-encoded semaphorin protein receptor; AltName: CD_antigen=CD232; Flags: Precursor;+++[B4DHQ7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60256, highly similar to Plexin-C1 {ECO:0000313|EMBL:BAG58219.1};+++[F5H3A2_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000439225};+++[F8VUW4_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447843}; Flags: Fragment;+++[F8W095_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447625}; Flags: Fragment;+++[F8W1K6_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000446781};"]
[10155,"'TRIM28'",4089,4504,5031,4541.33333333333,{"$nulls":4},"GO:0005720///nuclear heterochromatin+++GO:0000785///chromatin+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005719///nuclear euchromatin","GO:0043565///sequence-specific DNA binding+++GO:0035851///Krueppel-associated box domain binding+++GO:1990841///promoter-specific chromatin binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0070087///chromo shadow domain binding+++GO:0003714///transcription corepressor activity+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0007566///embryo implantation+++GO:0016567///protein ubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0060669///embryonic placenta morphogenesis+++GO:1901536///negative regulation of DNA demethylation+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0060028///convergent extension involved in axis elongation+++GO:0006281///DNA repair+++GO:0007265///Ras protein signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0051259///protein complex oligomerization+++GO:1902187///negative regulation of viral release from host cell+++GO:0045087///innate immune response+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:2000653///regulation of genetic imprinting+++GO:0042307///positive regulation of protein import into nucleus+++GO:0006325///chromatin organization+++GO:0016925///protein sumoylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045739///positive regulation of DNA repair+++GO:0006468///protein phosphorylation+++GO:0043045///DNA methylation involved in embryo development+++GO:0016032///viral process+++GO:0043388///positive regulation of DNA binding","tripartite motif containing 28","[TIF1B_HUMAN|Reviewed]RecName: Full=Transcription intermediary factor 1-beta; Short=TIF1-beta; AltName: Full=E3 SUMO-protein ligase TRIM28; EC=2.3.2.27; AltName: Full=KRAB-associated protein 1; Short=KAP-1; AltName: Full=KRAB-interacting protein 1; Short=KRIP-1; AltName: Full=Nuclear corepressor KAP-1; AltName: Full=RING finger protein 96; AltName: Full=RING-type E3 ubiquitin transferase TIF1-beta {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 28;+++[M0QZE6_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000470503}; Flags: Fragment;+++[M0R0K9_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000471303}; Flags: Fragment;+++[M0R2I3_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000472586}; Flags: Fragment;+++[M0R3C0_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000473126}; Flags: Fragment;"]
[10156,"'RASA4'",275.33,310.71,286.37,290.803333333333,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding+++GO:0005543///phospholipid binding","GO:0071277///cellular response to calcium ion+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0034260///negative regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0007165///signal transduction","RAS p21 protein activator 4","[RASL2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4; AltName: Full=Calcium-promoted Ras inactivator; AltName: Full=Ras p21 protein activator 4; AltName: Full=RasGAP-activating-like protein 2;+++[A0A087WUJ9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000478719};+++[B7ZL55_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI43585.1};+++[E5RGQ8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428732}; Flags: Fragment;+++[E5RID2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428448}; Flags: Fragment;+++[E5RK78_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430418}; Flags: Fragment;+++[E7ERK1_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000417395};+++[H0YB35_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428605}; Flags: Fragment;+++[H0YBU2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430337}; Flags: Fragment;+++[Q2NL74_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI10874.1};"]
[10157,"'AASS'",400.27,355,314.47,356.58,"01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00310///Lysine degradation+++01100///Metabolic pathways","H01242///Saccharopinuria+++H00188///Hyperlysinemia","M00032///Lysine degradation, lysine => saccharopine => acetoacetyl-CoA","R02313///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase; N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADH + H++++R00716///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADPH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0047130///saccharopine dehydrogenase (NADP+, L-lysine-forming) activity+++GO:0047131///saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity+++GO:0004753///saccharopine dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0003824///catalytic activity","GO:0019878///lysine biosynthetic process via aminoadipic acid+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine+++GO:0051262///protein tetramerization+++GO:0006554///lysine catabolic process+++GO:0019477///L-lysine catabolic process+++GO:0055114///oxidation-reduction process+++GO:0008152///metabolic process","aminoadipate-semialdehyde synthase","[AASS_HUMAN|Reviewed]RecName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial; AltName: Full=LKR/SDH; Includes: RecName: Full=Lysine ketoglutarate reductase; Short=LKR; Short=LOR; EC=1.5.1.8; Includes: RecName: Full=Saccharopine dehydrogenase; Short=SDH; EC=1.5.1.9; Flags: Precursor;+++[A4D0W4_HUMAN|Unreviewed]SubName: Full=Aminoadipate-semialdehyde synthase, isoform CRA_a {ECO:0000313|EMBL:EAW83564.1};+++[F8WAH1_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000351834};+++[F8WE53_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000414001};+++[H7C0C6_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000394180}; Flags: Fragment;"]
[10158,"'PDZK1IP1'",26,24,27,25.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane",null,null,"PDZK1 interacting protein 1","[PDZ1I_HUMAN|Reviewed]RecName: Full=PDZK1-interacting protein 1; AltName: Full=17 kDa membrane-associated protein; AltName: Full=Protein DD96;"]
[10159,"'ATP6AP2'",1733,2185,1898,1938.66666666667,"04614///Renin-angiotensin system","H00658///Syndromic X-linked mental retardation",null,null,"GO:0044297///cell body+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0009897///external side of plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection","GO:0038023///signaling receptor activity+++GO:0019899///enzyme binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0060323///head morphogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021903///rostrocaudal neural tube patterning+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0048069///eye pigmentation+++GO:0002003///angiotensin maturation+++GO:0043408///regulation of MAPK cascade","ATPase H+ transporting accessory protein 2","[RENR_HUMAN|Reviewed]RecName: Full=Renin receptor; AltName: Full=ATPase H(+)-transporting lysosomal accessory protein 2; AltName: Full=ATPase H(+)-transporting lysosomal-interacting protein 2; AltName: Full=ER-localized type I transmembrane adaptor; AltName: Full=Embryonic liver differentiation factor 10; AltName: Full=N14F; AltName: Full=Renin/prorenin receptor; AltName: Full=Vacuolar ATP synthase membrane sector-associated protein M8-9; Short=ATP6M8-9; Short=V-ATPase M8.9 subunit; Flags: Precursor;+++[A0A1B0GTB0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489622}; Flags: Fragment;+++[A0A1B0GTD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489653};+++[A0A1B0GTU8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489845};+++[A0A1B0GU12_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489920};+++[A0A1B0GUT7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490239};+++[A0A1B0GUV3_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490257}; Flags: Fragment;+++[A0A1B0GV24_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490345};+++[A0A1B0GV60_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490382};+++[A0A1B0GVB9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490452};+++[A0A1B0GVC7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490462};+++[A0A1B0GVI9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490532};+++[A0A1B0GVW0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490675};+++[A0A1B0GVZ1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490706};+++[A0A1B0GW13_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490733};+++[A0A1B0GWD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490884}; Flags: Fragment;+++[A0A1B0GWJ8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490954};+++[A0A1C7CYW4_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000367697};+++[B7Z1I9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59846, highly similar to Renin receptor {ECO:0000313|EMBL:BAH11525.1};+++[B7Z413_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52527, highly similar to Renin receptor {ECO:0000313|EMBL:BAH12399.1};+++[H7C240_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000403969}; Flags: Fragment;+++[H7C3E1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000411317};"]
[1016,"'CDH18'",3,1,0,1.33333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0005913///cell-cell adherens junction+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex","GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0045294///alpha-catenin binding+++GO:0070097///delta-catenin binding+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0008013///beta-catenin binding","GO:0007155///cell adhesion+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0098609///cell-cell adhesion+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0044331///cell-cell adhesion mediated by cadherin","cadherin 18","[CAD18_HUMAN|Reviewed]RecName: Full=Cadherin-18; AltName: Full=Cadherin-14; Flags: Precursor;+++[D6RER2_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000424931};+++[D6RIH8_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000425854};+++[H0YAK3_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000427383}; Flags: Fragment;"]
[10160,"'FARP1'",1329,1379,1137,1281.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0048365///Rac GTPase binding","GO:0007275///multicellular organism development+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:0010923///negative regulation of phosphatase activity+++GO:1905606///regulation of presynapse assembly+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048813///dendrite morphogenesis+++GO:0007416///synapse assembly+++GO:0098974///postsynaptic actin cytoskeleton organization","FERM, ARH/RhoGEF and pleckstrin domain protein 1","[FARP1_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1; AltName: Full=Chondrocyte-derived ezrin-like protein; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 1; AltName: Full=Pleckstrin homology domain-containing family C member 2; Short=PH domain-containing family C member 2;+++[A0A1B0GV68_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000490391};+++[A0A2X0TVY0_HUMAN|Unreviewed]SubName: Full=FARP1 {ECO:0000313|EMBL:SPT35756.1}; SubName: Full=FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived) {ECO:0000313|EMBL:EAX08982.1}; Flags: Fragment;+++[C9JME2_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000471242};+++[H0Y783_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410930}; Flags: Fragment;+++[M0QXT1_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469365}; Flags: Fragment;+++[M0QYB0_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469712}; Flags: Fragment;+++[M0R262_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472346}; Flags: Fragment;"]
[10161,"'LPAR6'",0,4,8,4,"04151///PI3K-Akt signaling pathway+++04072///Phospholipase D signaling pathway+++05200///Pathways in cancer+++04080///Neuroactive ligand-receptor interaction","H00667///Woolly hair+++H00784///Localized autosomal recessive hypotrichosis",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0001835///blastocyst hatching+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction","lysophosphatidic acid receptor 6","[LPAR6_HUMAN|Reviewed]RecName: Full=Lysophosphatidic acid receptor 6; Short=LPA receptor 6; Short=LPA-6; AltName: Full=Oleoyl-L-alpha-lysophosphatidic acid receptor; AltName: Full=P2Y purinoceptor 5; Short=P2Y5; AltName: Full=Purinergic receptor 5; AltName: Full=RB intron encoded G-protein coupled receptor;+++[A0A024RDT2_HUMAN|Unreviewed]SubName: Full=HCG30749, isoform CRA_a {ECO:0000313|EMBL:EAX08797.1};+++[B3KVQ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41064 fis, clone TRACH2001021, highly similar to P2Y PURINOCEPTOR 5 {ECO:0000313|EMBL:BAG53867.1};"]
[10162,"'LPCAT3'",986,809,849,881.333333333333,"00564///Glycerophospholipid metabolism+++04216///Ferroptosis",null,null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase   Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:0006629///lipid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling","lysophosphatidylcholine acyltransferase 3","[MBOA5_HUMAN|Reviewed]RecName: Full=Lysophospholipid acyltransferase 5; Short=LPLAT 5; EC=2.3.1.-; AltName: Full=1-acylglycerophosphocholine O-acyltransferase; EC=2.3.1.23; AltName: Full=1-acylglycerophosphoserine O-acyltransferase; EC=2.3.1.n6; AltName: Full=Lysophosphatidylcholine acyltransferase; Short=LPCAT; Short=Lyso-PC acyltransferase; AltName: Full=Lysophosphatidylcholine acyltransferase 3; Short=Lyso-PC acyltransferase 3; AltName: Full=Lysophosphatidylserine acyltransferase; Short=LPSAT; Short=Lyso-PS acyltransferase; AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 5; Short=O-acyltransferase domain-containing protein 5;+++[B7Z3N5_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000443166}; SubName: Full=cDNA FLJ59910, highly similar to Membrane bound O-acyltransferase domain-containing protein 5 {ECO:0000313|EMBL:BAH12271.1};+++[F5GYT3_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000440550};+++[F5H0M4_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000438765};+++[F5H680_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000437827};+++[F5H7K7_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000442454};"]
[10163,"'WASF2'",2707,2736,2489,2644,"05132///Salmonella infection+++05231///Choline metabolism in cancer+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005911///cell-cell junction+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0031209///SCAR complex+++GO:0001726///ruffle+++GO:0005769///early endosome","GO:0045296///cadherin binding+++GO:0003779///actin binding+++GO:0017124///SH3 domain binding+++GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0035855///megakaryocyte development+++GO:0030032///lamellipodium assembly+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0001667///ameboidal-type cell migration+++GO:0030048///actin filament-based movement+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0001525///angiogenesis+++GO:0051497///negative regulation of stress fiber assembly+++GO:0006897///endocytosis+++GO:0016601///Rac protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0072673///lamellipodium morphogenesis+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0016032///viral process","WAS protein family member 2","[WASF2_HUMAN|Reviewed]RecName: Full=Wiskott-Aldrich syndrome protein family member 2; Short=WASP family protein member 2; AltName: Full=Protein WAVE-2; AltName: Full=Verprolin homology domain-containing protein 2;+++[Q05BU7_HUMAN|Unreviewed]SubName: Full=WASF2 protein {ECO:0000313|EMBL:AAH32724.1}; Flags: Fragment;"]
[10164,"'CHST4'",0,0,1,0.333333333333333,"00533///Glycosaminoglycan biosynthesis - keratan sulfate",{"$nulls":3},"GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0031228///intrinsic component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0016740///transferase activity","GO:0006955///immune response+++GO:0006790///sulfur compound metabolic process+++GO:0007267///cell-cell signaling+++GO:0006954///inflammatory response+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006477///protein sulfation+++GO:0016266///O-glycan processing+++GO:0007155///cell adhesion+++GO:0005975///carbohydrate metabolic process","carbohydrate sulfotransferase 4","[CHST4_HUMAN|Reviewed]RecName: Full=Carbohydrate sulfotransferase 4; EC=2.8.2.-; AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; Short=GST-3; AltName: Full=High endothelial cells N-acetylglucosamine 6-O-sulfotransferase; Short=HEC-GlcNAc6ST; AltName: Full=L-selectin ligand sulfotransferase; Short=LSST; AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 2; Short=GlcNAc6ST-2; Short=Gn6st-2;"]
[10165,"'SLC25A13'",741,571,629,647,null,"H01305///Global cerebral hypomyelination+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00185///Citrullinemia (CTLN)",null,null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion","GO:0015183///L-aspartate transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0005313///L-glutamate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015172///acidic amino acid transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0005215///transporter activity+++GO:0046872///metal ion binding","GO:0006839///mitochondrial transport+++GO:0015810///aspartate transmembrane transport+++GO:0055085///transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0015813///L-glutamate transmembrane transport+++GO:0045333///cellular respiration+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0043490///malate-aspartate shuttle+++GO:0051592///response to calcium ion+++GO:0070778///L-aspartate transmembrane transport+++GO:0006094///gluconeogenesis","solute carrier family 25 member 13","[CMC2_HUMAN|Reviewed]RecName: Full=Calcium-binding mitochondrial carrier protein Aralar2; AltName: Full=Citrin; AltName: Full=Mitochondrial aspartate glutamate carrier 2; AltName: Full=Solute carrier family 25 member 13;+++[Q75KX8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07527.1}; Flags: Fragment;+++[Q75M55_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07513.1}; Flags: Fragment;+++[R4GN64_HUMAN|Unreviewed]SubName: Full=Calcium-binding mitochondrial carrier protein Aralar2 {ECO:0000313|Ensembl:ENSP00000473505};"]
[10166,"'SLC25A15'",107.47,70,105.71,94.3933333333333,null,"H01268///Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005664///nuclear origin of replication recognition complex+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0022857///transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0000064///L-ornithine transmembrane transporter activity","GO:0033314///mitotic DNA replication checkpoint+++GO:1990575///mitochondrial L-ornithine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0000050///urea cycle+++GO:0006270///DNA replication initiation+++GO:0000278///mitotic cell cycle+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006260///DNA replication","solute carrier family 25 member 15","[ORNT1_HUMAN|Reviewed]RecName: Full=Mitochondrial ornithine transporter 1; AltName: Full=Solute carrier family 25 member 15;+++[F2Z354_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000431429};+++[Q5VZD9_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000415826}; Flags: Fragment;"]
[10168,"'ZNF197'",132.62,259,214,201.873333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 197","[ZN197_HUMAN|Reviewed]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[C9JIP4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000390115}; Flags: Fragment;+++[C9JQH5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000394713}; Flags: Fragment;+++[F8WDZ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000402483};+++[F8WEU5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000334616};+++[M0QYR3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000470025};+++[Q4G1C8_HUMAN|Unreviewed]SubName: Full=ZNF197 protein {ECO:0000313|EMBL:AAH17584.1}; Flags: Fragment;+++[Q7Z6G1_HUMAN|Unreviewed]SubName: Full=Znf197 truncated protein {ECO:0000313|EMBL:AAP57399.1}; Flags: Fragment;+++[Q86XA2_HUMAN|Unreviewed]SubName: Full=ZNF20 protein {ECO:0000313|EMBL:AAH45814.1};"]
[10169,"'SERF2'",6336,6954,7782,7024,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008150///biological_process","small EDRK-rich factor 2","[SERF2_HUMAN|Reviewed]RecName: Full=Small EDRK-rich factor 2; AltName: Full=Gastric cancer-related protein VRG107; AltName: Full=Protein 4F5-related; Short=4F5rel; Short=h4F5rel;+++[B8ZZY7_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386316};+++[B9A031_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000387041};+++[C9JQZ0_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000394660}; Flags: Fragment;+++[F8WBN3_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386290};+++[F8WBV6_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000391027};"]
[1017,"'CDK2'",226,186,214,208.666666666667,"04934///Cushing's syndrome+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++04914///Progesterone-mediated oocyte maturation+++05226///Gastric cancer+++05215///Prostate cancer+++04151///PI3K-Akt signaling pathway+++04114///Oocyte meiosis+++05200///Pathways in cancer+++05162///Measles+++04218///Cellular senescence+++05203///Viral carcinogenesis+++04110///Cell cycle+++05168///Herpes simplex infection+++04068///FoxO signaling pathway+++05161///Hepatitis B+++05222///Small cell lung cancer+++05169///Epstein-Barr virus infection",null,"M00692///Cell cycle - G1/S transition+++M00693///Cell cycle - G2/M transition",null,"GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0097123///cyclin A1-CDK2 complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0000805///X chromosome+++GO:0097134///cyclin E1-CDK2 complex+++GO:0000781///chromosome, telomeric region+++GO:0097124///cyclin A2-CDK2 complex+++GO:0097135///cyclin E2-CDK2 complex+++GO:0000806///Y chromosome+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000793///condensed chromosome+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0015030///Cajal body+++GO:0005856///cytoskeleton","GO:0097472///cyclin-dependent protein kinase activity+++GO:0035173///histone kinase activity+++GO:0000287///magnesium ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0000166///nucleotide binding+++GO:0019904///protein domain specific binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0046872///metal ion binding","GO:0051301///cell division+++GO:0016310///phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006260///DNA replication+++GO:0006468///protein phosphorylation+++GO:0006813///potassium ion transport+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0018105///peptidyl-serine phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006281///DNA repair+++GO:0008284///positive regulation of cell proliferation+++GO:0032298///positive regulation of DNA-dependent DNA replication initiation+++GO:0051726///regulation of cell cycle+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0007099///centriole replication+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051298///centrosome duplication+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060968///regulation of gene silencing+++GO:0007049///cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016572///histone phosphorylation","cyclin dependent kinase 2","[CDK2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2; EC=2.7.11.22 {ECO:0000269|PubMed:1396589, ECO:0000269|PubMed:28666995, ECO:0000269|PubMed:9030781}; AltName: Full=Cell division protein kinase 2; AltName: Full=p33 protein kinase;+++[A0A024RB10_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW96857.1};+++[A0A024RB77_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_b {ECO:0000313|EMBL:EAW96860.1};+++[B4DDL9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54979, highly similar to Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG56780.1};+++[E7ESI2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000393605};+++[G3V317_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000450983};+++[G3V5T9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000452514}; SubName: Full=Cyclin-dependent kinase 2, isoform CRA_c {ECO:0000313|EMBL:EAW96859.1};"]
[10170,"'DHRS9'",0,0,3,1,"01100///Metabolic pathways+++00830///Retinol metabolism",null,null,"R02124///retinol:NAD+ oxidoreductase   Retinol + NAD+ <=> Retinal + NADH + H+","GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0016854///racemase and epimerase activity+++GO:0016491///oxidoreductase activity+++GO:0004745///retinol dehydrogenase activity+++GO:0004022///alcohol dehydrogenase (NAD) activity","GO:0042572///retinol metabolic process+++GO:0030855///epithelial cell differentiation+++GO:0055114///oxidation-reduction process+++GO:0002138///retinoic acid biosynthetic process+++GO:0008209///androgen metabolic process+++GO:0042904///9-cis-retinoic acid biosynthetic process+++GO:0042448///progesterone metabolic process","dehydrogenase/reductase 9","[DHRS9_HUMAN|Reviewed]RecName: Full=Dehydrogenase/reductase SDR family member 9; EC=1.1.-.-; AltName: Full=3-alpha hydroxysteroid dehydrogenase; Short=3-alpha-HSD; AltName: Full=NADP-dependent retinol dehydrogenase/reductase; AltName: Full=RDH-E2; AltName: Full=RDHL; AltName: Full=Retinol dehydrogenase 15; AltName: Full=Short chain dehydrogenase/reductase family 9C member 4; AltName: Full=Short-chain dehydrogenase/reductase retSDR8; AltName: Full=Tracheobronchial epithelial cell-specific retinol dehydrogenase; Short=RDH-TBE; Flags: Precursor;+++[C9J430_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 9 {ECO:0000313|Ensembl:ENSP00000391214}; Flags: Fragment;+++[Q4ZG83_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RDHL {ECO:0000313|EMBL:AAX88964.1}; Flags: Fragment;+++[Q53TL1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RDHL {ECO:0000313|EMBL:AAY24306.1}; Flags: Fragment;"]
[10171,"'RCL1'",144,135,137,138.666666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003824///catalytic activity+++GO:0004521///endoribonuclease activity","GO:0042254///ribosome biogenesis+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006396///RNA processing+++GO:0006364///rRNA processing+++GO:0008150///biological_process+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","RNA terminal phosphate cyclase like 1","[RCL1_HUMAN|Reviewed]RecName: Full=RNA 3'-terminal phosphate cyclase-like protein;+++[Q5VYW8_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000371151};+++[Q5VZU2_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000413381}; Flags: Fragment;+++[Q5VZU3_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000412000};"]
[10172,"'ZNF256'",57,36,31,41.3333333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 256","[ZN256_HUMAN|Reviewed]RecName: Full=Zinc finger protein 256; AltName: Full=Bone marrow zinc finger 3; Short=BMZF-3;+++[L8E7T8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF256 {ECO:0000313|EMBL:CCQ43335.1};+++[M0R2X0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 256 {ECO:0000313|Ensembl:ENSP00000472858};"]
[10174,"'SORBS3'",3081,3259,3680,3340,"04022///cGMP-PKG signaling pathway+++04662///B cell receptor signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04728///Dopaminergic synapse+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++04720///Long-term potentiation+++05014///Amyotrophic lateral sclerosis (ALS)+++04724///Glutamatergic synapse+++04380///Osteoclast differentiation+++04218///Cellular senescence+++05010///Alzheimer's disease+++04137///Mitophagy - animal+++04658///Th1 and Th2 cell differentiation+++04660///T cell receptor signaling pathway+++04659///Th17 cell differentiation+++04360///Axon guidance+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04370///VEGF signaling pathway+++04010///MAPK signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05031///Amphetamine addiction+++04310///Wnt signaling pathway+++04020///Calcium signaling pathway+++04625///C-type lectin receptor signaling pathway+++05166///HTLV-I infection+++04921///Oxytocin signaling pathway","H02150///Infantile or early childhood epileptic encephalopathy",null,null,"GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005856///cytoskeleton","GO:0017166///vinculin binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0008134///transcription factor binding","GO:0051495///positive regulation of cytoskeleton organization+++GO:0006936///muscle contraction+++GO:0043410///positive regulation of MAPK cascade+++GO:0051496///positive regulation of stress fiber assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0031589///cell-substrate adhesion+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion","sorbin and SH3 domain containing 3","[VINEX_HUMAN|Reviewed]RecName: Full=Vinexin; AltName: Full=SH3-containing adapter molecule 1; Short=SCAM-1; AltName: Full=Sorbin and SH3 domain-containing protein 3;+++[E5RIA0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429479}; Flags: Fragment;+++[E5RJP2_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000431128}; Flags: Fragment;+++[E7EQH0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429723};+++[H0YAU6_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428102}; Flags: Fragment;+++[H0YAZ3_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428327}; Flags: Fragment;+++[H0YB51_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428678}; Flags: Fragment;+++[Q9BT70_HUMAN|Unreviewed]SubName: Full=SORBS3 protein {ECO:0000313|EMBL:AAH04314.1}; Flags: Fragment;"]
[10175,"'CNIH1'",622,542,546,570,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0012507///ER to Golgi transport vesicle membrane",null,"GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","cornichon family AMPA receptor auxiliary protein 1","[CNIH1_HUMAN|Reviewed]RecName: Full=Protein cornichon homolog 1; Short=CNIH-1; AltName: Full=Cornichon family AMPA receptor auxiliary protein 1; AltName: Full=Protein cornichon homolog; AltName: Full=T-cell growth-associated molecule 77; Short=TGAM77;+++[A8MVW4_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW80636.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000378940};+++[B2R4P1_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW80635.1}; SubName: Full=cDNA FLJ90300 fis, clone NT2RP2000533, highly similar to Cornichon homolog {ECO:0000313|EMBL:BAG52000.1}; SubName: Full=cDNA, FLJ92163, Homo sapiens cornichon homolog (Drosophila) (CNIH), mRNA {ECO:0000313|EMBL:BAG34838.1};+++[G3V3B2_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451142};+++[G3V474_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451640};+++[G3V4K0_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAW80637.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451852};+++[G3V5P8_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452457};+++[G3V5Q6_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452466};"]
[10178,"'TENM1'",4,8,6,6,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0043005///neuron projection+++GO:0016363///nuclear matrix+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0008201///heparin binding+++GO:0042803///protein homodimerization activity+++GO:0050839///cell adhesion molecule binding","GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0006955///immune response+++GO:0007218///neuropeptide signaling pathway+++GO:0090316///positive regulation of intracellular protein transport+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007165///signal transduction+++GO:0043406///positive regulation of MAP kinase activity+++GO:0008285///negative regulation of cell proliferation+++GO:0051491///positive regulation of filopodium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0048666///neuron development+++GO:0007399///nervous system development","teneurin transmembrane protein 1","[TEN1_HUMAN|Reviewed]RecName: Full=Teneurin-1; Short=Ten-1; AltName: Full=Protein Odd Oz/ten-m homolog 1; AltName: Full=Tenascin-M1; Short=Ten-m1; AltName: Full=Teneurin transmembrane protein 1; Contains: RecName: Full=Ten-1 intracellular domain; Short=IDten-1; Short=Ten-1 ICD; Contains: RecName: Full=Teneurin C-terminal-associated peptide; Short=TCPA-1; AltName: Full=Ten-1 extracellular domain; Short=Ten-1 ECD;+++[B7ZMH4_HUMAN|Unreviewed]SubName: Full=ODZ1 protein {ECO:0000313|EMBL:AAI44544.1};+++[G3CAS6_HUMAN|Unreviewed]SubName: Full=Odz, odd Oz/ten-m homolog 1 (Drosophila) {ECO:0000313|EMBL:CCD17865.1}; Flags: Fragment;+++[L8EAN5_HUMAN|Unreviewed]SubName: Full=Alternative protein ODZ1 {ECO:0000313|EMBL:CCQ43428.1};"]
[10179,"'RBM7'",247,247,284,259.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding","GO:0051321///meiotic cell cycle+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 7","[RBM7_HUMAN|Reviewed]RecName: Full=RNA-binding protein 7; AltName: Full=RNA-binding motif protein 7;+++[F5GXV8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440949};+++[F5GY08_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440923};+++[F5H606_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437998};+++[F5H674_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437847};+++[G3V1T9_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_a {ECO:0000313|EMBL:EAW67246.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000445848};+++[J3KPD3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_c {ECO:0000313|EMBL:EAW67248.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000364639};+++[Q6IRX3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7 {ECO:0000313|EMBL:AAH70262.1};"]
[1018,"'CDK3'",41,50,51,47.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0045023///G0 to G1 transition+++GO:0007049///cell cycle+++GO:0006468///protein phosphorylation+++GO:0008283///cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051301///cell division+++GO:0016310///phosphorylation","cyclin dependent kinase 3","[CDK3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 3; EC=2.7.11.22; AltName: Full=Cell division protein kinase 3;+++[A0A024R8R3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3, isoform CRA_a {ECO:0000313|EMBL:EAW89354.1};+++[K7EJ83_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000465062}; Flags: Fragment;+++[K7ELV5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000466237}; Flags: Fragment;"]
[10180,"'RBM6'",919,953,834,902,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006396///RNA processing","RNA binding motif protein 6","[RBM6_HUMAN|Reviewed]RecName: Full=RNA-binding protein 6; AltName: Full=Lung cancer antigen NY-LU-12; AltName: Full=Protein G16; AltName: Full=RNA-binding motif protein 6; AltName: Full=RNA-binding protein DEF-3;+++[A8K6Q4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76888, highly similar to Homo sapiens RNA binding motif protein 6 (RBM6), mRNA {ECO:0000313|EMBL:BAF84408.1};+++[C9J250_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000392475};+++[C9JII0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000403865}; Flags: Fragment;+++[C9JMC8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000389763}; Flags: Fragment;+++[C9JSL1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000394336}; Flags: Fragment;+++[E9PGM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396466};+++[F8WCA5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000406548};+++[F8WCT0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396410};+++[F8WF63_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000399942};"]
[10181,"'RBM5'",1544,1540,1429,1504.33333333333,null,"H00943///TARP syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0008380///RNA splicing+++GO:0008285///negative regulation of cell proliferation+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006915///apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000245///spliceosomal complex assembly+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process","RNA binding motif protein 5","[RBM5_HUMAN|Reviewed]RecName: Full=RNA-binding protein 5; AltName: Full=Protein G15; AltName: Full=Putative tumor suppressor LUCA15; AltName: Full=RNA-binding motif protein 5; AltName: Full=Renal carcinoma antigen NY-REN-9;+++[A0A024R2U6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW65042.1};+++[A0A0S2Z549_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 1 {ECO:0000313|EMBL:ALQ33963.1}; Flags: Fragment;+++[A0A0S2Z5U0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 2 {ECO:0000313|EMBL:ALQ33964.1};+++[C9J9P7_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000406119}; Flags: Fragment;+++[C9JFQ5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000390711}; Flags: Fragment;+++[C9JR02_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000394622}; Flags: Fragment;+++[E1CJT4_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 variant {ECO:0000313|EMBL:BAJ19019.1};+++[F8W910_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000384872}; Flags: Fragment;+++[F8WE23_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000414218};+++[H7BYM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000378603}; Flags: Fragment;"]
[10184,"'LHFPL2'",1242,1308,1148,1232.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0031092///platelet alpha granule membrane+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0007338///single fertilization+++GO:1905516///positive regulation of fertilization+++GO:0002576///platelet degranulation+++GO:0046545///development of primary female sexual characteristics+++GO:0008150///biological_process+++GO:0046546///development of primary male sexual characteristics","LHFPL tetraspan subfamily member 2","[LHPL2_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 2 protein {ECO:0000312|HGNC:HGNC:6588}; AltName: Full=Lipoma HMGIC fusion partner-like 2 protein {ECO:0000312|HGNC:HGNC:6588};+++[A0A024RAM8_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW95819.1};"]
[10186,"'LHFPL6'",4425,3113,3187,3575,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","LHFPL tetraspan subfamily member 6","[LHPL6_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 6 protein {ECO:0000312|HGNC:HGNC:6586}; AltName: Full=Lipoma HMGIC fusion partner {ECO:0000312|HGNC:HGNC:6586}; Flags: Precursor;+++[A0A024RDR1_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner, isoform CRA_a {ECO:0000313|EMBL:EAX08617.1};"]
[10188,"'TNK2'",682,768,829,759.666666666667,{"$nulls":4},"GO:0005912///adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0097268///cytoophidium+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0070436///Grb2-EGFR complex+++GO:0005634///nucleus+++GO:0030136///clathrin-coated vesicle+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005905///clathrin-coated pit","GO:0016740///transferase activity+++GO:0005095///GTPase inhibitor activity+++GO:0042802///identical protein binding+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0050699///WW domain binding+++GO:0046872///metal ion binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0007264///small GTPase mediated signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0034260///negative regulation of GTPase activity+++GO:0030154///cell differentiation+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation","tyrosine kinase non receptor 2","[ACK1_HUMAN|Reviewed]RecName: Full=Activated CDC42 kinase 1; Short=ACK-1; EC=2.7.10.2 {ECO:0000269|PubMed:10652228, ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:16472662, ECO:0000269|PubMed:18993068, ECO:0000269|PubMed:20333297}; EC=2.7.11.1 {ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:18993068}; AltName: Full=Tyrosine kinase non-receptor protein 2;+++[B3KXJ4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45547 fis, clone BRTHA2035743, highly similar to Activated CDC42 kinase 1 {ECO:0000313|EMBL:BAG54506.1};+++[C9J1X3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392546};+++[C9JDG3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000395154}; Flags: Fragment;+++[C9JIR5_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390088}; Flags: Fragment;+++[F8WER3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000393707};+++[H0Y5H7_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000398614}; Flags: Fragment;+++[H7BZM8_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390435}; Flags: Fragment;+++[H7BZZ3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392253}; Flags: Fragment;+++[H7C343_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000409462}; Flags: Fragment;+++[H7C412_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000415126}; Flags: Fragment;"]
[10189,"'ALYREF'",777,876,968,873.666666666667,"03013///RNA transport+++03040///Spliceosome+++05168///Herpes simplex infection+++03015///mRNA surveillance pathway",null,"M00406///TREX complex+++M00430///Exon junction complex (EJC)",null,"GO:0005681///spliceosomal complex+++GO:0070062///extracellular exosome+++GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0000784///nuclear chromosome, telomeric region+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0031124///mRNA 3'-end processing+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0001649///osteoblast differentiation+++GO:0051028///mRNA transport+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0016032///viral process+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000018///regulation of DNA recombination+++GO:0031297///replication fork processing","Aly/REF export factor","[THOC4_HUMAN|Reviewed]RecName: Full=THO complex subunit 4; Short=Tho4; AltName: Full=Ally of AML-1 and LEF-1; AltName: Full=Aly/REF export factor; AltName: Full=Transcriptional coactivator Aly/REF; AltName: Full=bZIP-enhancing factor BEF;+++[E9PB61_HUMAN|Unreviewed]SubName: Full=THO complex subunit 4 {ECO:0000313|Ensembl:ENSP00000421592};"]
[1019,"'CDK4'",1209,1420,1408,1345.66666666667,"05200///Pathways in cancer+++05162///Measles+++05223///Non-small cell lung cancer+++04115///p53 signaling pathway+++05166///HTLV-I infection+++05224///Breast cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05222///Small cell lung cancer+++05165///Human papillomavirus infection+++04110///Cell cycle+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++05219///Bladder cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05161///Hepatitis B+++04218///Cellular senescence+++05212///Pancreatic cancer+++05218///Melanoma+++05225///Hepatocellular carcinoma+++01522///Endocrine resistance+++05163///Human cytomegalovirus infection+++05220///Chronic myeloid leukemia+++05214///Glioma+++04660///T cell receptor signaling pathway+++04530///Tight junction+++04934///Cushing's syndrome","H00042///Glioma+++H00030///Cervical cancer+++H00038///Melanoma","M00692///Cell cycle - G1/S transition",null,"GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005730///nucleolus+++GO:0097129///cyclin D2-CDK4 complex+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000785///chromatin+++GO:0005923///bicellular tight junction+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005667///transcription factor complex","GO:0030332///cyclin binding+++GO:0016740///transferase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0044877///protein-containing complex binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0071157///negative regulation of cell cycle arrest+++GO:0046890///regulation of lipid biosynthetic process+++GO:0033574///response to testosterone+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0032869///cellular response to insulin stimulus+++GO:0071353///cellular response to interleukin-4+++GO:0050994///regulation of lipid catabolic process+++GO:0060612///adipose tissue development+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:0010033///response to organic substance+++GO:0043065///positive regulation of apoptotic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0002088///lens development in camera-type eye+++GO:0016310///phosphorylation+++GO:0010468///regulation of gene expression+++GO:0006468///protein phosphorylation+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007623///circadian rhythm+++GO:0055093///response to hyperoxia+++GO:0045727///positive regulation of translation+++GO:0045793///positive regulation of cell size+++GO:0051301///cell division+++GO:0007165///signal transduction+++GO:0040014///regulation of multicellular organism growth+++GO:0031100///animal organ regeneration+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:1904637///cellular response to ionomycin+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010288///response to lead ion+++GO:0009636///response to toxic substance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity","cyclin dependent kinase 4","[CDK4_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4; EC=2.7.11.22; AltName: Full=Cell division protein kinase 4; AltName: Full=PSK-J3;+++[A0A024RBB6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4, isoform CRA_a {ECO:0000313|EMBL:EAW97060.1};+++[F8VTV8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448098};+++[F8VWX7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449179}; Flags: Fragment;+++[F8VXD2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449391}; Flags: Fragment;+++[F8VYH9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448963}; Flags: Fragment;+++[F8VYY1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448885};+++[F8VZ13_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447005};+++[F8VZ51_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447779}; Flags: Fragment;+++[F8VZZ0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447274}; Flags: Fragment;+++[F8W1L8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000446763}; Flags: Fragment;+++[Q6LC83_HUMAN|Unreviewed]SubName: Full=Cyclin dependent protein kinase {ECO:0000313|EMBL:AAB50213.1}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_b {ECO:0000313|EMBL:EAW97059.1};+++[Q96BE9_HUMAN|Unreviewed]SubName: Full=CDK4 protein {ECO:0000313|EMBL:AAH15669.1}; SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000316889}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_c {ECO:0000313|EMBL:EAW97061.1};"]
[10190,"'TXNDC9'",258,257,274,263,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0008150///biological_process+++GO:0045454///cell redox homeostasis","thioredoxin domain containing 9","[TXND9_HUMAN|Reviewed]RecName: Full=Thioredoxin domain-containing protein 9; AltName: Full=ATP-binding protein associated with cell differentiation; AltName: Full=Protein 1-4;+++[B8ZZX4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000386889}; Flags: Fragment;+++[F8WBV5_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000391046};+++[F8WCJ3_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000406388};+++[G3XAJ4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain containing 9, isoform CRA_a {ECO:0000313|EMBL:EAX01868.1}; SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000402827};"]
[101927245,"'LOC101927245'",7,7,12,8.66666666666667,{"$nulls":7},"vegetative cell wall protein gp1-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927262,"'LOC101927262'",2,4,1,2.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0030971///receptor tyrosine kinase binding+++GO:0030298///receptor signaling protein tyrosine kinase activator activity","GO:0070378///positive regulation of ERK5 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0010976///positive regulation of neuron projection development","melanoma-associated antigen C1-like","[ALKL1_HUMAN|diamond]RecName: Full=ALK and LTK ligand 1 {ECO:0000312|HGNC:HGNC:33775}; AltName: Full=Augmentor beta {ECO:0000303|PubMed:26630010}; Short=AUG-beta {ECO:0000303|PubMed:26630010}; AltName: Full=Protein FAM150A; Flags: Precursor;+++[ALKL1_MOUSE|diamond]RecName: Full=ALK and LTK ligand 1; AltName: Full=Augmentor beta; AltName: Full=Protein FAM150A; Flags: Precursor;+++[ALKL2_HUMAN|diamond]RecName: Full=ALK and LTK ligand 2 {ECO:0000312|HGNC:HGNC:27683}; AltName: Full=Augmentor alpha {ECO:0000303|PubMed:26630010}; Short=AUG-alpha {ECO:0000303|PubMed:26630010}; AltName: Full=Protein FAM150B; Flags: Precursor;+++[ALKL2_MOUSE|diamond]RecName: Full=ALK and LTK ligand 2; AltName: Full=Protein FAM150B; Flags: Precursor;+++[ALKL2_RAT|diamond]RecName: Full=ALK and LTK ligand 2; AltName: Full=Protein FAM150B; Flags: Precursor;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[MST2_DROHY|diamond]RecName: Full=Axoneme-associated protein mst101(2);+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927322,"'LOC101927322'",1,3,6,3.33333333333333,"04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++05152///Tuberculosis+++04064///NF-kappa B signaling pathway+++04662///B cell receptor signaling pathway",{"$nulls":3},"GO:0005730///nucleolus+++GO:0001650///fibrillar center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0032449///CBM complex+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0002020///protease binding+++GO:0043621///protein self-association+++GO:0042802///identical protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008233///peptidase activity","GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002726///positive regulation of T cell cytokine production+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006508///proteolysis+++GO:0050852///T cell receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:2000321///positive regulation of T-helper 17 cell differentiation+++GO:0051259///protein complex oligomerization+++GO:0001923///B-1 B cell differentiation+++GO:0009620///response to fungus+++GO:0002237///response to molecule of bacterial origin+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051168///nuclear export+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0042098///T cell proliferation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0006952///defense response+++GO:0032743///positive regulation of interleukin-2 production","uncharacterized LOC101927322","[MALT1_HUMAN|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1; EC=3.4.22.-; AltName: Full=MALT lymphoma-associated translocation; AltName: Full=Paracaspase;+++[MALT1_MOUSE|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; EC=3.4.22.-; AltName: Full=Paracaspase;"]
[101927345,"'LOC101927345'",27.58,51,38.14,38.9066666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"putative ankyrin repeat domain-containing protein 20A12 pseudogene","[A2012_HUMAN|diamond]RecName: Full=Putative ankyrin repeat domain-containing protein 20A12 pseudogene {ECO:0000305};+++[AN18A_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18A;+++[AN18B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18B;+++[ANR26_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000305};+++[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[SNX18_MOUSE|diamond]RecName: Full=Sorting nexin-18; AltName: Full=Sorting nexin-associated Golgi protein 1;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927401,"'LOC101927401'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0016604///nuclear body+++GO:0005886///plasma membrane+++GO:0030018///Z disc+++GO:0005829///cytosol+++GO:0031430///M band+++GO:0030016///myofibril+++GO:0042383///sarcolemma","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0008307///structural constituent of muscle+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005524///ATP binding+++GO:0031432///titin binding+++GO:0005516///calmodulin binding+++GO:0030506///ankyrin binding+++GO:0004674///protein serine/threonine kinase activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007275///multicellular organism development+++GO:0036309///protein localization to M-band+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0045214///sarcomere organization+++GO:0035023///regulation of Rho protein signal transduction","MAGE-like protein 2","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[OBSCN_HUMAN|diamond]RecName: Full=Obscurin; EC=2.7.11.1 {ECO:0000250|UniProtKB:A2AAJ9}; AltName: Full=Obscurin-RhoGEF; AltName: Full=Obscurin-myosin light chain kinase; Short=Obscurin-MLCK;+++[OBSCN_MOUSE|diamond]RecName: Full=Obscurin; EC=2.7.11.1 {ECO:0000269|PubMed:23392350}; AltName: Full=Obscurin-RhoGEF; AltName: Full=Obscurin-myosin light chain kinase; Short=Obscurin-MLCK;+++[SPEG_DANRE|diamond]RecName: Full=Striated muscle preferentially expressed protein kinase; EC=2.7.11.1;+++[SPEG_MOUSE|diamond]RecName: Full=Striated muscle-specific serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[SPEG_RAT|diamond]RecName: Full=Striated muscle-specific serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927423,"'PANO1'",27,28,36,30.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus",null,"GO:0031647///regulation of protein stability+++GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process","proapoptotic nucleolar protein 1","[PANO1_HUMAN|Reviewed]RecName: Full=Proapoptotic nucleolar protein 1 {ECO:0000303|PubMed:22094112, ECO:0000312|HGNC:HGNC:51237};"]
[101927506,"'LOC101927506'",219.91,167.69,134.96,174.186666666667,"01100///Metabolic pathways+++04137///Mitophagy - animal+++00380///Tryptophan metabolism+++04140///Autophagy - animal",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin+++R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0005525///GTP binding","GO:0006310///DNA recombination+++GO:0007049///cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division+++GO:0032199///reverse transcription involved in RNA-mediated transposition","uncharacterized LOC101927506","[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NP10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Np9 protein; AltName: Full=HERV-K10 Np9 protein; AltName: Full=HERV-K107 Np9 protein; AltName: Full=HERV-K_5q33.3 provirus Np9 protein;+++[NP24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Np9 protein; AltName: Full=HERV-K101 Np9 protein; AltName: Full=HERV-K_22q11.21 provirus Np9 protein;+++[NP5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Np9 protein; AltName: Full=Endogenous retrovirus K protein 5; AltName: Full=HERV-K(II) Np9 protein; AltName: Full=HERV-K_3q12.3 provirus Np9 protein;+++[NP7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Np9 protein; AltName: Full=HERV-K(III) Np9 protein; AltName: Full=HERV-K102 Np9 protein; AltName: Full=HERV-K_1q22 provirus Np9 protein;+++[PRORY_HUMAN|diamond]RecName: Full=Proline-rich protein, Y-linked;+++[RL23A_BOVIN|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_HUMAN|diamond]RecName: Full=60S ribosomal protein L23a; AltName: Full=Large ribosomal subunit protein uL23 {ECO:0000303|PubMed:24524803};+++[RL23A_MOUSE|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_RAT|diamond]RecName: Full=60S ribosomal protein L23a;+++[SEP14_BOVIN|diamond]RecName: Full=Septin-14;+++[SEP14_HUMAN|diamond]RecName: Full=Septin-14;+++[SEP14_MOUSE|diamond]RecName: Full=Septin-14;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927509,"'LOC101927509'",22,30,33,28.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","basic proline-rich protein-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927572,"'LOC101927572'",0,0,2,0.666666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005795///Golgi stack+++GO:0032588///trans-Golgi network membrane+++GO:0005886///plasma membrane+++GO:0031901///early endosome membrane+++GO:0045121///membrane raft+++GO:0055038///recycling endosome membrane+++GO:0005802///trans-Golgi network","GO:0035594///ganglioside binding+++GO:0008017///microtubule binding","GO:0010828///positive regulation of glucose transmembrane transport+++GO:0072321///chaperone-mediated protein transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0001934///positive regulation of protein phosphorylation+++GO:0044091///membrane biogenesis+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0043065///positive regulation of apoptotic process+++GO:0045807///positive regulation of endocytosis+++GO:0045444///fat cell differentiation+++GO:0031115///negative regulation of microtubule polymerization","uncharacterized LOC101927572","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CLIP3_HUMAN|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP3_MOUSE|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP3_PONAB|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP3_XENLA|diamond]RecName: Full=CAP-Gly domain-containing linker protein 3; AltName: Full=Cytoplasmic linker protein 170-related 59 kDa protein; Short=CLIP-170-related 59 kDa protein; Short=CLIPR-59;+++[CLIP4_HUMAN|diamond]RecName: Full=CAP-Gly domain-containing linker protein 4; AltName: Full=Restin-like protein 2;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[KANK3_HUMAN|diamond]RecName: Full=KN motif and ankyrin repeat domain-containing protein 3; AltName: Full=Ankyrin repeat domain-containing protein 47;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927601,"'GOLGA6L19'",0,0.59,16.13,5.57333333333333,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"golgin A6 family-like 19","[GG6LS_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 19;"]
[101927655,"'ZASP'",0,2.84,0,0.946666666666667,{"$nulls":7},"ZO-2 associated speckle protein","[E3Q1N2_HUMAN|Unreviewed]SubName: Full=ZO-2 associated speckle protein {ECO:0000313|EMBL:CBX53310.1};"]
[101927789,"'LOC101927789'",14,23,28,21.6666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated","putative ubiquitin-like protein FUBI-like protein ENSP00000310146","[GT2D2_BOVIN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GT2D2_MOUSE|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GTD2A_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2A; Short=GTF2I repeat domain-containing protein 2A; AltName: Full=Transcription factor GTF2IRD2-alpha;+++[GTD2B_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2B; Short=GTF2I repeat domain-containing protein 2B; AltName: Full=Transcription factor GTF2IRD2-beta;+++[NANGN_HUMAN|diamond]RecName: Full=NANOG neighbor homeobox; AltName: Full=Homeobox protein C14;+++[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[UBIML_HUMAN|diamond]RecName: Full=Putative ubiquitin-like protein FUBI-like protein ENSP00000310146;+++[UBIM_MOUSE|diamond]RecName: Full=Ubiquitin-like protein FUBI; AltName: Full=Monoclonal non-specific suppressor factor beta; Short=MNSF-beta;+++[UBIM_MUSSI|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_PIG|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_RAT|diamond]RecName: Full=Ubiquitin-like protein FUBI;"]
[101927824,"'LOC101927824'",5,1,2,2.66666666666667,{"$nulls":7},"translation initiation factor IF-2-like","[A0A1D5R5M3_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000055611};+++[A0A2K5TP44_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000001824};+++[A0A2K5UCW2_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000010203};+++[I7G9B2_MACFA|diamond]SubName: Full=Macaca fascicularis brain cDNA clone: QtrA-16029, similar to human glycoprotein VI (platelet) (GP6), mRNA, RefSeq: NM_016363.3 {ECO:0000313|EMBL:BAE91381.1};+++[Q95K85_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAB60791.1};"]
[101928095,"'LOC101928095'",4.56,10.74,14.19,9.83,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0003677///DNA binding+++GO:0004984///olfactory receptor activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0008270///zinc ion binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0015074///DNA integration+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0006310///DNA recombination","serine/arginine-rich splicing factor RSZ22-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[O7E24_HUMAN|diamond]RecName: Full=Olfactory receptor 7E24; AltName: Full=Olfactory receptor OR19-14;+++[OLF18_MOUSE|diamond]RecName: Full=Olfactory receptor 18; AltName: Full=Olfactory receptor 145-1; AltName: Full=Olfactory receptor TPCR34;+++[OR7AA_HUMAN|diamond]RecName: Full=Olfactory receptor 7A10; AltName: Full=OST027; AltName: Full=Olfactory receptor OR19-18;+++[OR7C2_HUMAN|diamond]RecName: Full=Olfactory receptor 7C2; AltName: Full=Olfactory receptor 19-18; Short=OR19-18; AltName: Full=Olfactory receptor 7C3; AltName: Full=Olfactory receptor OR19-22;+++[OR7D4_HUMAN|diamond]RecName: Full=Olfactory receptor 7D4; AltName: Full=OR19-B; AltName: Full=Odorant receptor family subfamily D member 4RT; AltName: Full=Olfactory receptor OR19-7;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101928120,"'LOC101928120'",27,37,22,28.6666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:1990907///beta-catenin-TCF complex","GO:0035034///histone acetyltransferase regulator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0030879///mammary gland development+++GO:0048589///developmental growth+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0001701///in utero embryonic development+++GO:0035563///positive regulation of chromatin binding+++GO:0002088///lens development in camera-type eye+++GO:0001822///kidney development+++GO:0009791///post-embryonic development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060021///roof of mouth development+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0007420///brain development+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0007289///spermatid nucleus differentiation","uncharacterized LOC101928120","[PYGO2_HUMAN|diamond]RecName: Full=Pygopus homolog 2;"]
[101928212,"'LOC101928212'",9,4,12,8.33333333333333,{"$nulls":4},"GO:0030176///integral component of endoplasmic reticulum membrane","GO:0061513///glucose 6-phosphate:inorganic phosphate antiporter activity","GO:0015760///glucose-6-phosphate transport","uncharacterized LOC101928212","[A0A2K6U6V0_SAIBB|diamond]SubName: Full=Solute carrier family 37 member 1 {ECO:0000313|Ensembl:ENSSBOP00000027629};"]
[101928422,"'LOC101928422'",34,44.02,41.65,39.89,{"$nulls":4},"GO:0030054///cell junction+++GO:0005886///plasma membrane","GO:0044325///ion channel binding","GO:0090314///positive regulation of protein targeting to membrane+++GO:0030335///positive regulation of cell migration+++GO:0010360///negative regulation of anion channel activity","TRPM8 channel-associated factor 2-like","[TCAF1_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF1_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[TCAF1_PONAB|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF2_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF2_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 2 {ECO:0000303|PubMed:25559186};+++[TCAF2_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF3_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000312|MGI:MGI:3042585}; AltName: Full=Experimental autoimmune prostatitis antigen 2;+++[TCAF3_RAT|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000305}; AltName: Full=Experimental autoimmune prostatitis antigen 2 homolog;"]
[101928448,"'C5orf67'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0022625///cytosolic large ribosomal subunit+++GO:0022626///cytosolic ribosome","GO:0048027///mRNA 5'-UTR binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:1902167///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006412///translation+++GO:1904803///regulation of translation involved in cellular response to UV+++GO:0006413///translational initiation+++GO:0042273///ribosomal large subunit biogenesis+++GO:0034644///cellular response to UV+++GO:0002181///cytoplasmic translation+++GO:0071480///cellular response to gamma radiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006364///rRNA processing+++GO:0045727///positive regulation of translation+++GO:1902164///positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","chromosome 5 open reading frame 67","[CE067_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf67;+++[A0A087WXD6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C5orf67 {ECO:0000313|Ensembl:ENSP00000480926};"]
[101928527,"'PIGBOS1'",91,96,59.01,82.0033333333333,{"$nulls":4},"GO:0005576///extracellular region",null,null,"PIGB opposite strand 1","[PIOS1_HUMAN|Reviewed]RecName: Full=Protein PIGBOS1 {ECO:0000305}; AltName: Full=PIGB opposite strand protein {ECO:0000312|HGNC:HGNC:50696}; Flags: Precursor;+++[A0A087WXK0_HUMAN|Unreviewed]SubName: Full=Protein PIGBOS1 {ECO:0000313|Ensembl:ENSP00000481097}; Flags: Fragment;"]
[101928589,"'LOC101928589'",4.57,113.76,255.21,124.513333333333,{"$nulls":7},"uncharacterized LOC101928589","[A0A2Y9R3X6_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC111821147 {ECO:0000313|RefSeq:XP_023590205.1};+++[D3DUY5_HUMAN|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX02668.1}; Flags: Fragment;+++[G7NT51_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH30994.1}; Flags: Fragment;+++[G7Q3G6_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH61145.1}; Flags: Fragment;+++[Q9NXL7_HUMAN|diamond]SubName: Full=cDNA FLJ20173 fis, clone COL09814 {ECO:0000313|EMBL:BAA90993.1};"]
[101928592,"'LOC101928592'",1,0,3,1.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated","zinc finger protein OZF-like","[ZFP2_HUMAN|diamond]RecName: Full=Zinc finger protein 2 homolog; Short=Zfp-2; AltName: Full=Zinc finger protein 751;+++[ZFP2_MOUSE|diamond]RecName: Full=Zinc finger protein 2; Short=Zfp-2; AltName: Full=Protein mKR2;+++[ZKSC1_MOUSE|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;+++[ZKSC1_PONAB|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;+++[ZKSC7_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 7; AltName: Full=Zinc finger protein 167; AltName: Full=Zinc finger protein 448; AltName: Full=Zinc finger protein 64;+++[ZKSC8_PANTR|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 8; AltName: Full=Zinc finger protein 192;+++[ZN180_HUMAN|diamond]RecName: Full=Zinc finger protein 180; AltName: Full=HHZ168;+++[ZN197_HUMAN|diamond]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[ZN445_HUMAN|diamond]RecName: Full=Zinc finger protein 445; AltName: Full=Zinc finger protein 168; AltName: Full=Zinc finger protein with KRAB and SCAN domains 15;+++[ZNF3_HUMAN|diamond]RecName: Full=Zinc finger protein 3; AltName: Full=Zinc finger protein HF.12; AltName: Full=Zinc finger protein HZF3.1; AltName: Full=Zinc finger protein KOX25;"]
[101928601,"'MEI4'",6,1,0,2.33333333333333,{"$nulls":4},"GO:0005694///chromosome+++GO:0000800///lateral element","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0051321///meiotic cell cycle+++GO:0042138///meiotic DNA double-strand break formation+++GO:0048477///oogenesis+++GO:0007129///synapsis+++GO:0007283///spermatogenesis+++GO:0006310///DNA recombination","meiotic double-stranded break formation protein 4","[MEI4_HUMAN|Reviewed]RecName: Full=Meiosis-specific protein MEI4;"]
[101928635,"'LOC101928635'",10,7,12,9.66666666666667,"01100///Metabolic pathways+++04979///Cholesterol metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++00561///Glycerolipid metabolism+++04976///Bile secretion",null,"M00098///Acylglycerol degradation","R02250///triacylglycerol acylhydrolase Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase 1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid","GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016323///basolateral plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0034364///high-density lipoprotein particle+++GO:0016021///integral component of membrane","GO:0004806///triglyceride lipase activity+++GO:0004620///phospholipase activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0005345///purine nucleobase transmembrane transporter activity+++GO:0015288///porin activity+++GO:0046872///metal ion binding+++GO:0005372///water transmembrane transporter activity+++GO:0004170///dUTP diphosphatase activity+++GO:0046943///carboxylic acid transmembrane transporter activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0000287///magnesium ion binding+++GO:0015265///urea channel activity+++GO:0003677///DNA binding+++GO:0034185///apolipoprotein binding+++GO:0005350///pyrimidine nucleobase transmembrane transporter activity+++GO:0015166///polyol transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0008201///heparin binding+++GO:0051213///dioxygenase activity+++GO:0005275///amine transmembrane transporter activity+++GO:0015254///glycerol channel activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0015837///amine transport+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0006633///fatty acid biosynthetic process+++GO:0007588///excretion+++GO:0046942///carboxylic acid transport+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0034382///chylomicron remnant clearance+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006226///dUMP biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0015791///polyol transport+++GO:0006863///purine nucleobase transport+++GO:0034373///intermediate-density lipoprotein particle remodeling+++GO:0070328///triglyceride homeostasis+++GO:0010468///regulation of gene expression+++GO:0006955///immune response+++GO:0032197///transposition, RNA-mediated+++GO:0010033///response to organic substance+++GO:0006970///response to osmotic stress+++GO:0015855///pyrimidine nucleobase transport+++GO:0030104///water homeostasis+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0046689///response to mercury ion+++GO:0034638///phosphatidylcholine catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0019433///triglyceride catabolic process+++GO:0071320///cellular response to cAMP+++GO:0015793///glycerol transport+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0015722///canalicular bile acid transport+++GO:0046081///dUTP catabolic process+++GO:0006833///water transport+++GO:0043691///reverse cholesterol transport+++GO:0006310///DNA recombination","uncharacterized LOC101928635","[AQP10_MILTA|diamond]RecName: Full=Aquaporin-10 {ECO:0000303|PubMed:23761966}; Short=AQP-10 {ECO:0000303|PubMed:23761966};+++[AQP3_MOUSE|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=Aquaglyceroporin-3;+++[AQP3_RAT|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=31.4 kDa water channel protein; AltName: Full=Aquaglyceroporin-3;+++[AQP9_HUMAN|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9; AltName: Full=Small solute channel 1;+++[AQP9_MOUSE|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[AQP9_RAT|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DUT_HUMAN|diamond]RecName: Full=Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; Short=dUTPase; EC=3.6.1.23; AltName: Full=dUTP pyrophosphatase; Flags: Precursor;+++[DUTL_HUMAN|diamond]RecName: Full=Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323; Short=dUTPase-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LIPC_BOVIN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_HUMAN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_MOUSE|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RABIT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RAT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYL10_HUMAN|diamond]RecName: Full=Myosin regulatory light chain 10; AltName: Full=Myosin light chain 2, lymphocyte-specific; AltName: Full=Precursor lymphocyte-specific regulatory light chain;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928722,"'LOC101928722'",1,1,1,1,{"$nulls":4},"GO:0005813///centrosome","GO:0008017///microtubule binding","GO:0034453///microtubule anchoring","nascent polypeptide-associated complex subunit alpha, muscle-specific form-like","[A0A0D9RT94_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000011833};+++[A0A1W2PQX5_HUMAN|diamond]SubName: Full=Coiled-coil domain-containing protein 187 {ECO:0000313|Ensembl:ENSP00000492326};+++[A0A2I2Z933_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000043611};+++[A0A2R8ZH59_PANPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000003079};+++[H2RG04_PANTR|diamond]SubName: Full=CCDC187 isoform 3 {ECO:0000313|EMBL:PNI68580.1}; SubName: Full=Coiled-coil domain containing 187 {ECO:0000313|Ensembl:ENSPTRP00000060450};"]
[101928764,"'LOC101928764'",6,8,5,6.33333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005604///basement membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:0007154///cell communication+++GO:0048839///inner ear development+++GO:0001654///eye development+++GO:0042733///embryonic digit morphogenesis+++GO:0007507///heart development+++GO:0002009///morphogenesis of an epithelium","coiled-coil domain-containing protein 144B","[FREM2_HUMAN|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; Flags: Precursor;+++[FREM2_MOUSE|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; AltName: Full=NV domain-containing protein 1; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[POTB2_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B2;+++[POTB3_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B3 {ECO:0000312|HGNC:HGNC:51240};+++[POTEA_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member A; AltName: Full=ANKRD26-like family A member 1; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 8; Short=POTE-8;+++[POTEB_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B {ECO:0000305}; AltName: Full=ANKRD26-like family B member 1 {ECO:0000305}; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 15 {ECO:0000303|PubMed:15276201}; Short=POTE-15 {ECO:0000303|PubMed:15276201};+++[POTEC_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member C; AltName: Full=ANKRD26-like family B member 2; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 18; Short=POTE-18;"]
[101928841,"'LOC101928841'",29.56,24.01,19.05,24.2066666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","collagen alpha-1(II) chain-like","[FIBH_BOMMO|diamond]RecName: Full=Fibroin heavy chain; Short=Fib-H; AltName: Full=H-fibroin; Flags: Precursor;+++[PHXR5_MOUSE|diamond]RecName: Full=Putative per-hexamer repeat protein 5;+++[TPRX1_HUMAN|diamond]RecName: Full=Tetra-peptide repeat homeobox protein 1;+++[TSEP_GLOPP|diamond]RecName: Full=Protein TsetseEP; AltName: Full=EP-repeat protein; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928991,"'CCDC92B'",4.23,18.16,19,13.7966666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity",null,"coiled-coil domain containing 92B","[CCD92_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 92; AltName: Full=Limkain beta-2;+++[CCD92_MOUSE|diamond]RecName: Full=Coiled-coil domain-containing protein 92;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929097,"'101929097'",134.08,133,159.2,142.093333333333,{"$nulls":8},"[H2NWX9_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000010497};+++[Q9H7L4_HUMAN|diamond]SubName: Full=FLJ00058 protein {ECO:0000313|EMBL:BAB15755.1}; Flags: Fragment;"]
[101929141,"'LOC101929141'",5.98,6.25,1.17,4.46666666666667,{"$nulls":7},"coiled-coil domain-containing protein 144B-like","[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;+++[C144B_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144B;+++[C144C_HUMAN|diamond]RecName: Full=Putative coiled-coil domain-containing protein 144C; AltName: Full=Coiled-coil domain-containing protein 144C pseudogene;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[POTEE_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member E; AltName: Full=ANKRD26-like family C member 1A; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 2; Short=POTE-2;+++[POTEF_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member F; AltName: Full=ANKRD26-like family C member 1B; AltName: Full=Chimeric POTE-actin protein;"]
[101929235,"'LOC101929235'",0.5,0,0,0.166666666666667,{"$nulls":7},"putative ubiquitin-conjugating enzyme E2Q2-like protein","[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;+++[UB2Q2_BOVIN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_HUMAN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_MOUSE|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_RABIT|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-conjugating enzyme UBCi; AltName: Full=Ubiquitin-protein ligase Q2;"]
[101929322,"'LOC101929322'",343,294,266,301,{"$nulls":4},"GO:0005829///cytosol+++GO:0032587///ruffle membrane+++GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0016020///membrane","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding","GO:0043410///positive regulation of MAPK cascade+++GO:0000165///MAPK cascade+++GO:0016180///snRNA processing+++GO:0019933///cAMP-mediated signaling+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0006468///protein phosphorylation","integrator complex subunit 4 pseudogene","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[INT4_DICDI|diamond]RecName: Full=Integrator complex subunit 4 homolog;+++[INT4_DROME|diamond]RecName: Full=Integrator complex subunit 4 {ECO:0000303|PubMed:21078872};+++[INT4_HUMAN|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_MOUSE|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_XENLA|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929400,"'LOC101929400'",2.18,7.31,7.8,5.76333333333333,{"$nulls":5},"GO:0003723///RNA binding",null,"uncharacterized LOC101929400","[A0A2I2ZER1_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000045561};+++[A0A2I3HCP8_NOMLE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000041428};+++[A0A2I3T7A9_PANTR|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNI44179.1}; SubName: Full=RNA binding fox-1 homolog 1 {ECO:0000313|Ensembl:ENSPTRP00000085111};+++[A0A2J8SEY9_PONAB|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNJ19325.1};+++[A0A2J8SEZ1_PONAB|diamond]SubName: Full=RBFOX1 isoform 24 {ECO:0000313|EMBL:PNJ19336.1};"]
[101929479,"'LOC101929479'",499.64,547.63,448.01,498.426666666667,{"$nulls":4},"GO:0043202///lysosomal lumen+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0032580///Golgi cisterna membrane+++GO:0005796///Golgi lumen+++GO:0031258///lamellipodium membrane+++GO:0000922///spindle pole+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0016324///apical plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0072686///mitotic spindle","GO:0045296///cadherin binding+++GO:0061676///importin-alpha family protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0019905///syntaxin binding+++GO:0019901///protein kinase binding","GO:0007020///microtubule nucleation+++GO:0060050///positive regulation of protein glycosylation+++GO:0001525///angiogenesis+++GO:0006486///protein glycosylation+++GO:0051289///protein homotetramerization+++GO:0051225///spindle assembly+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0010507///negative regulation of autophagy+++GO:0090307///mitotic spindle assembly+++GO:0000187///activation of MAPK activity+++GO:0030207///chondroitin sulfate catabolic process+++GO:0048771///tissue remodeling+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0090161///Golgi ribbon formation+++GO:0090166///Golgi disassembly+++GO:0090306///spindle assembly involved in meiosis+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0032091///negative regulation of protein binding+++GO:0008356///asymmetric cell division+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0008283///cell proliferation+++GO:0007098///centrosome cycle+++GO:0035556///intracellular signal transduction+++GO:0008347///glial cell migration","golgin subfamily A member 2","[CSPG4_HUMAN|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Melanoma chondroitin sulfate proteoglycan; AltName: Full=Melanoma-associated chondroitin sulfate proteoglycan; Flags: Precursor;+++[CSPG4_MOUSE|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Proteoglycan AN2; Flags: Precursor;+++[CSPG4_RAT|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=HSN tumor-specific antigen; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DYN1_BOVIN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_HUMAN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_MOUSE|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_RAT|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5; AltName: Full=B-dynamin; AltName: Full=D100; AltName: Full=Dynamin, brain;+++[GGA2B_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 2B; AltName: Full=Golgin subfamily A member 2-like protein 1;+++[GOG6A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6A; AltName: Full=Golgin linked to PML; AltName: Full=Golgin-like protein;+++[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8A; AltName: Full=88 kDa Golgi matrix protein; Short=GM88; AltName: Full=GM88 autoantigen;+++[GOG8B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8B; AltName: Full=Golgin-67;+++[GOG8C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8C;+++[GOG8D_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POLY_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon gypsy; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;"]
[101929599,"'LOC101929599'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"putative POM121-like protein 1-like pseudogene","[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[101929738,"'LOC101929738'",0,0,2,0.666666666666667,{"$nulls":7},"putative POM121-like protein 1","[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[101929747,"'101929747'",3.89,3.69,12.84,6.80666666666667,{"$nulls":8},"[A0A2Y9JJD1_ENHLU|diamond]SubName: Full=uncharacterized protein LOC111148452 {ECO:0000313|RefSeq:XP_022360711.1};"]
[101929796,"'NOTCH2NLR'",86.02,85.15,69.28,80.15,"04330///Notch signaling pathway+++01522///Endocrine resistance+++04658///Th1 and Th2 cell differentiation+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++04320///Dorso-ventral axis formation","H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0005654///nucleoplasm+++GO:0043235///receptor complex+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005576///extracellular region","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007399///nervous system development+++GO:0007219///Notch signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006915///apoptotic process+++GO:0002315///marginal zone B cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007050///cell cycle arrest+++GO:0003184///pulmonary valve morphogenesis+++GO:0046849///bone remodeling+++GO:2001204///regulation of osteoclast development+++GO:0030097///hemopoiesis+++GO:0060413///atrial septum morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0001709///cell fate determination+++GO:0045967///negative regulation of growth rate+++GO:0009887///animal organ morphogenesis+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0061314///Notch signaling involved in heart development+++GO:0019827///stem cell population maintenance+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","notch 2 N-terminal like R","[NOTC2_HUMAN|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Short=hN2; Contains: RecName: Full=Notch 2 extracellular truncation; Short=N2ECD {ECO:0000303|PubMed:25985737}; Contains: RecName: Full=Notch 2 intracellular domain; Short=N2ICD {ECO:0000303|PubMed:25985737}; Flags: Precursor;+++[NOTC2_RAT|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Contains: RecName: Full=Notch 2 extracellular truncation; Contains: RecName: Full=Notch 2 intracellular domain; Flags: Precursor;+++[NT2NA_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[NT2NC_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[101929895,"'LOC101929895'",5,4,6,5,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0043209///myelin sheath+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0008017///microtubule binding+++GO:0015631///tubulin binding","GO:0031334///positive regulation of protein complex assembly+++GO:0001578///microtubule bundle formation+++GO:0046785///microtubule polymerization+++GO:0032273///positive regulation of protein polymerization","uncharacterized LOC101929895","[TPPP_BOVIN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=p25-alpha;+++[TPPP_HUMAN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=TPPP/p25; AltName: Full=p24; AltName: Full=p25-alpha;+++[TPPP_MOUSE|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP;"]
[101929937,"'LOC101929937'",1,0,2,1,null,"H00773///Autosomal dominant mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0032993///protein-DNA complex+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0030133///transport vesicle","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0021510///spinal cord development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045165///cell fate commitment+++GO:0065004///protein-DNA complex assembly","uncharacterized LOC101929937","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[NRSN2_HUMAN|diamond]RecName: Full=Neurensin-2;+++[NRSN2_MOUSE|diamond]RecName: Full=Neurensin-2;+++[SOX11_CHICK|diamond]RecName: Full=Transcription factor SOX-11; Short=cSox11;+++[SOX11_XENTR|diamond]RecName: Full=Transcription factor Sox-11;+++[SOX12_HUMAN|diamond]RecName: Full=Transcription factor SOX-12; AltName: Full=Protein SOX-22;+++[SOX12_MOUSE|diamond]RecName: Full=Transcription factor SOX-12;+++[SX11B_XENLA|diamond]RecName: Full=Transcription factor Sox-11-B; AltName: Full=Transcription factor Sox-13; Short=xSox-13; AltName: Full=XLS13B;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929950,"'LOC101929950'",17.06,12.38,13.56,14.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0042277///peptide binding","GO:0006508///proteolysis+++GO:0043171///peptide catabolic process","puromycin-sensitive aminopeptidase-like protein","[ERAP1_MOUSE|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 1; EC=3.4.11.-; AltName: Full=ARTS-1; AltName: Full=Adipocyte-derived leucine aminopeptidase; Short=A-LAP; AltName: Full=Aminopeptidase PILS; AltName: Full=Puromycin-insensitive leucyl-specific aminopeptidase; Short=PILS-AP; AltName: Full=VEGF-induced aminopeptidase;+++[ERAP2_BOVIN|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 2; EC=3.4.11.-;+++[PSA_CAEEL|diamond]RecName: Full=Puromycin-sensitive aminopeptidase {ECO:0000303|PubMed:12930831}; Short=PSA {ECO:0000305}; EC=3.4.11.14 {ECO:0000305|PubMed:12930831}; AltName: Full=Cytosol alanyl aminopeptidase {ECO:0000305}; Short=AAP-S {ECO:0000305};+++[PSA_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;+++[PSAL_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase-like protein; EC=3.4.11.-;+++[PSA_MOUSE|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;"]
[101929959,"'LOC101929959'",132.95,122.63,110.67,122.083333333333,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++03320///PPAR signaling pathway+++04140///Autophagy - animal+++04923///Regulation of lipolysis in adipocytes","H02106///Genetic obesity+++H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0030686///90S preribosome+++GO:0005730///nucleolus","GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0003723///RNA binding+++GO:0035252///UDP-xylosyltransferase activity+++GO:0034511///U3 snoRNA binding+++GO:0015267///channel activity+++GO:0003924///GTPase activity","GO:0006364///rRNA processing+++GO:0000479///endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0016266///O-glycan processing","ribosome biogenesis protein BMS1 homolog","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[AQP7_HUMAN|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7; AltName: Full=Aquaporin adipose; Short=AQPap; AltName: Full=Aquaporin-7-like;+++[AQP7_MACFA|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[AQP7_MOUSE|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[BMS1_HUMAN|diamond]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GXLT1_HUMAN|diamond]RecName: Full=Glucoside xylosyltransferase 1; EC=2.4.2.n2; AltName: Full=Glycosyltransferase 8 domain-containing protein 3;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[TSR1_DICDI|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_HUMAN|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_MOUSE|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_PONAB|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_XENLA|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10193,"'RNF41'",1038.24,1186.08,1040.76,1088.36,"04144///Endocytosis",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0071782///endoplasmic reticulum tubular network","GO:0004842///ubiquitin-protein transferase activity+++GO:0019904///protein domain specific binding+++GO:0017160///Ral GTPase binding+++GO:0005128///erythropoietin receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0005135///interleukin-3 receptor binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity","GO:0010498///proteasomal protein catabolic process+++GO:0051896///regulation of protein kinase B signaling+++GO:0051865///protein autoubiquitination+++GO:0006915///apoptotic process+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000114///regulation of establishment of cell polarity+++GO:0006914///autophagy+++GO:0045637///regulation of myeloid cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0010468///regulation of gene expression+++GO:1901525///negative regulation of mitophagy+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045619///regulation of lymphocyte differentiation+++GO:0000209///protein polyubiquitination+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0008285///negative regulation of cell proliferation+++GO:0043408///regulation of MAPK cascade+++GO:0016567///protein ubiquitination","ring finger protein 41","[RNF41_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase NRDP1; EC=2.3.2.27; AltName: Full=RING finger protein 41; AltName: Full=RING-type E3 ubiquitin transferase NRDP1 {ECO:0000305};+++[A0A024RB33_HUMAN|Unreviewed]SubName: Full=Ring finger protein 41, isoform CRA_b {ECO:0000313|EMBL:EAW96911.1};+++[F8VNZ6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000450164}; Flags: Fragment;+++[F8VSB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448187};+++[F8VSE5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448330};+++[F8VSP7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000446595}; Flags: Fragment;+++[F8VVY2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000449575};"]
[101930307,"'LOC101930307'",30,30,24,28,{"$nulls":4},"GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity","GO:0008152///metabolic process","uncharacterized LOC101930307","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10194,"'TSHZ1'",312,212,173,232.333333333333,"04391///Hippo signaling pathway - fly","H02115///Congenital aural atresia",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0009952///anterior/posterior pattern specification+++GO:0007275///multicellular organism development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060023///soft palate development+++GO:0042474///middle ear morphogenesis","teashirt zinc finger homeobox 1","[TSH1_HUMAN|Reviewed]RecName: Full=Teashirt homolog 1; AltName: Full=Antigen NY-CO-33; AltName: Full=Serologically defined colon cancer antigen 33;+++[A7YF73_HUMAN|Unreviewed]SubName: Full=TSHZ1 protein {ECO:0000313|EMBL:AAH24152.2}; Flags: Fragment;+++[H0YKA1_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000452718}; Flags: Fragment;+++[H0YN23_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000453834}; Flags: Fragment;"]
[10195,"'ALG3'",1753,1952,2373,2026,"00513///Various types of N-glycan biosynthesis+++00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R06258///Dolichyl phosphate D-mannose + G00006 <=> Dolichyl phosphate + G10595","GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0005515///protein binding+++GO:0052925///dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0000030///mannosyltransferase activity+++GO:0000033///alpha-1,3-mannosyltransferase activity","GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006486///protein glycosylation+++GO:0097502///mannosylation","ALG3, alpha-1,3- mannosyltransferase","[ALG3_HUMAN|Reviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; EC=2.4.1.258; AltName: Full=Asparagine-linked glycosylation protein 3 homolog; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase; AltName: Full=Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase; AltName: Full=Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase; AltName: Full=Not56-like protein;+++[C9J7S5_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047};+++[F8WE30_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000394917};+++[F8WF93_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000407011};+++[H7BZZ2_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000392209}; Flags: Fragment;+++[H7C0X4_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; Flags: Fragment;"]
[10196,"'PRMT3'",63,72,59,64.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,null,"R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol","GO:0008168///methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0043022///ribosome binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0034969///histone arginine methylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032259///methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006479///protein methylation","protein arginine methyltransferase 3","[ANM3_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 3; EC=2.1.1.-; AltName: Full=Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3;+++[E9PLF6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000435151};+++[E9PRB4_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000434260};+++[Q8WUV3_HUMAN|Unreviewed]SubName: Full=PRMT3 protein {ECO:0000313|EMBL:AAH19339.1}; Flags: Fragment;"]
[10197,"'PSME3'",2273,2316,2359,2316,"03050///Proteasome+++05160///Hepatitis C+++04612///Antigen processing and presentation",null,null,"R03139///primary-amine oxidase 1,3-Diaminopropane + Oxygen + H2O <=> 3-Aminopropanal + Ammonia + Hydrogen peroxide+++R06740///primary-amine oxidase Cadaverine + H2O + Oxygen <=> 5-Aminopentanal + Ammonia + Hydrogen peroxide+++R02613///Phenethylamine:oxygen oxidoreductase (deaminating) Phenethylamine + Oxygen + H2O <=> Phenylacetaldehyde + Ammonia + Hydrogen peroxide+++R06154///methylamine:oxygen oxidoreductase (deaminating) (copper-containing) Methylamine + Oxygen + H2O <=> Formaldehyde + Ammonia + Hydrogen peroxide+++R02529///aminoacetone:oxygen oxidoreductase(deaminating) Aminoacetone + H2O + Oxygen <=> Methylglyoxal + Ammonia + Hydrogen peroxide+++R02382///Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) Tyramine + H2O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04300///4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing) Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04027///primary-amine oxidase N-Methylputrescine + Oxygen + H+ <=> 1-Methylpyrrolinium + Hydrogen peroxide + Ammonia","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0008537///proteasome activator complex+++GO:0000502///proteasome complex","GO:0061133///endopeptidase activator activity+++GO:0002039///p53 binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007049///cell cycle+++GO:0043687///post-translational protein modification+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0006915///apoptotic process","proteasome activator subunit 3","[PSME3_HUMAN|Reviewed]RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma;+++[A0A024R203_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) activator subunit 3 (PA28 gamma Ki), isoform CRA_a {ECO:0000313|EMBL:EAW60894.1};+++[A0A087WTV2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000478159};+++[B3KQ25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32659 fis, clone TESTI1000045, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAG51887.1};+++[B7Z8D3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57249, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAH13919.1};+++[K7EJF8_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465155};+++[K7EKR3_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465743}; Flags: Fragment;+++[K7EMD0_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466451}; Flags: Fragment;+++[K7ENH2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466945}; Flags: Fragment;+++[K7EPX6_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000467580}; Flags: Fragment;+++[K7ESG5_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000468702};+++[K9J957_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000438237}; SubName: Full=REG gamma-3 variant {ECO:0000313|EMBL:ACO54885.1};+++[Q6FHK7_HUMAN|Unreviewed]SubName: Full=PSME3 protein {ECO:0000313|EMBL:CAG46545.1};+++[Q6MZZ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686J2076 {ECO:0000313|EMBL:CAE45884.1};+++[V9HWJ8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 283 {ECO:0000313|EMBL:ACJ13707.1};"]
[10198,"'MPHOSPH9'",189,195,143,175.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus",null,null,"M-phase phosphoprotein 9","[MPP9_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 9;+++[A0A0A0MTP3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000445859};+++[F5GYG6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440664}; Flags: Fragment;+++[F5GYP5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441298}; Flags: Fragment;+++[F5H1U6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446362}; Flags: Fragment;+++[F5H1W2_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446334}; Flags: Fragment;+++[F5H2I5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446249};+++[F5H798_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000442663};+++[H0YFS3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440007}; Flags: Fragment;+++[H0YG46_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441764}; Flags: Fragment;+++[J3KNE4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000304096}; Flags: Fragment;+++[U3KQ61_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475578}; Flags: Fragment;+++[U3KQD6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475785}; Flags: Fragment;+++[U3KQJ0_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475923}; Flags: Fragment;"]
[10199,"'MPHOSPH10'",339,326,351,338.666666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034457///Mpp10 complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006396///RNA processing+++GO:0042254///ribosome biogenesis+++GO:0010923///negative regulation of phosphatase activity+++GO:0006364///rRNA processing+++GO:0008380///RNA splicing","M-phase phosphoprotein 10","[MPP10_HUMAN|Reviewed]RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10; AltName: Full=M phase phosphoprotein 10;+++[U3KQ48_HUMAN|Unreviewed]SubName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000313|Ensembl:ENSP00000475545};"]
[102,"'ADAM10'",1925,2355,1777,2019,"05010///Alzheimer's disease+++05120///Epithelial cell signaling in Helicobacter pylori infection",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0030425///dendrite+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0043025///neuronal cell body+++GO:0070062///extracellular exosome+++GO:0070821///tertiary granule membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0098794///postsynapse+++GO:0005798///Golgi-associated vesicle+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion","GO:0004222///metalloendopeptidase activity+++GO:0019901///protein kinase binding+++GO:0008233///peptidase activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0017124///SH3 domain binding+++GO:0008237///metallopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0008284///positive regulation of cell proliferation+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0034205///amyloid-beta formation+++GO:0030307///positive regulation of cell growth+++GO:0001701///in utero embryonic development+++GO:0007162///negative regulation of cell adhesion+++GO:0043687///post-translational protein modification+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0007219///Notch signaling pathway+++GO:0016485///protein processing+++GO:0051089///constitutive protein ectodomain proteolysis+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0034612///response to tumor necrosis factor+++GO:0007283///spermatogenesis+++GO:0022617///extracellular matrix disassembly+++GO:0051088///PMA-inducible membrane protein ectodomain proteolysis+++GO:0006508///proteolysis+++GO:0007267///cell-cell signaling+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0007229///integrin-mediated signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0097327///response to antineoplastic agent+++GO:0006468///protein phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0043312///neutrophil degranulation+++GO:0099173///postsynapse organization+++GO:0042117///monocyte activation+++GO:0035333///Notch receptor processing, ligand-dependent+++GO:0043065///positive regulation of apoptotic process","ADAM metallopeptidase domain 10","[ADA10_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; EC=3.4.24.81 {ECO:0000269|PubMed:11477090, ECO:0000269|PubMed:12475894, ECO:0000269|PubMed:16239146, ECO:0000269|PubMed:17557115, ECO:0000269|PubMed:19114711, ECO:0000269|PubMed:20592283, ECO:0000269|PubMed:29224781}; AltName: Full=CDw156; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: CD_antigen=CD156c; Flags: Precursor;+++[A0A024R5U5_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase domain 10, isoform CRA_b {ECO:0000313|EMBL:EAW77541.1};+++[A0A087WYG1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000481779};+++[A0AV88_HUMAN|Unreviewed]SubName: Full=ADAM10 protein {ECO:0000313|EMBL:AAI26254.1};+++[B5MC71_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000386056};+++[C9J9B4_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000391930}; Flags: Fragment;+++[H0YK32_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452639};+++[H0YK87_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452704}; Flags: Fragment;+++[H0YNC5_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000453952}; Flags: Fragment;+++[H3BS53_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000456542}; Flags: Fragment;+++[L8E9R5_HUMAN|Unreviewed]SubName: Full=Alternative protein ADAM10 {ECO:0000313|EMBL:CCQ43088.1};"]
[1020,"'CDK5'",379,392,458,409.666666666667,"05010///Alzheimer's disease+++05030///Cocaine addiction+++04360///Axon guidance","H00268///Lissencephaly (LIS)",null,null,"GO:0005874///microtubule+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0043204///perikaryon+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0098794///postsynapse+++GO:0030424///axon+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane+++GO:0016533///protein kinase 5 complex+++GO:0030425///dendrite+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse","GO:0016301///kinase activity+++GO:0043125///ErbB-3 class receptor binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0002039///p53 binding+++GO:0050321///tau-protein kinase activity+++GO:0000166///nucleotide binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels+++GO:0051879///Hsp90 protein binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0048156///tau protein binding+++GO:0046875///ephrin receptor binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0030549///acetylcholine receptor activator activity+++GO:0005176///ErbB-2 class receptor binding+++GO:0008017///microtubule binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016740///transferase activity","GO:0007399///nervous system development+++GO:0051402///neuron apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008542///visual learning+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0032801///receptor catabolic process+++GO:0000226///microtubule cytoskeleton organization+++GO:0045861///negative regulation of proteolysis+++GO:0098883///synapse pruning+++GO:0032092///positive regulation of protein binding+++GO:0008306///associative learning+++GO:2000273///positive regulation of signaling receptor activity+++GO:0048813///dendrite morphogenesis+++GO:0071156///regulation of cell cycle arrest+++GO:0022038///corpus callosum development+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0008045///motor neuron axon guidance+++GO:0016079///synaptic vesicle exocytosis+++GO:0042220///response to cocaine+++GO:0008283///cell proliferation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0009611///response to wounding+++GO:0048489///synaptic vesicle transport+++GO:0070509///calcium ion import+++GO:0048812///neuron projection morphogenesis+++GO:0021695///cerebellar cortex development+++GO:0016241///regulation of macroautophagy+++GO:1904646///cellular response to amyloid-beta+++GO:0006886///intracellular protein transport+++GO:0035418///protein localization to synapse+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0021766///hippocampus development+++GO:0045860///positive regulation of protein kinase activity+++GO:0034352///positive regulation of glial cell apoptotic process+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:0031397///negative regulation of protein ubiquitination+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0007049///cell cycle+++GO:0030182///neuron differentiation+++GO:0046826///negative regulation of protein export from nucleus+++GO:0016572///histone phosphorylation+++GO:0030900///forebrain development+++GO:0048167///regulation of synaptic plasticity+++GO:0031175///neuron projection development+++GO:0048148///behavioral response to cocaine+++GO:0035249///synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0045055///regulated exocytosis+++GO:0007409///axonogenesis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0042501///serine phosphorylation of STAT protein+++GO:0006915///apoptotic process+++GO:0051301///cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0019233///sensory perception of pain+++GO:0014044///Schwann cell development+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0021697///cerebellar cortex formation+++GO:0006913///nucleocytoplasmic transport+++GO:0007519///skeletal muscle tissue development+++GO:0007005///mitochondrion organization+++GO:0021537///telencephalon development+++GO:0045786///negative regulation of cell cycle+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0048709///oligodendrocyte differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007160///cell-matrix adhesion+++GO:0021987///cerebral cortex development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0021954///central nervous system neuron development+++GO:0021819///layer formation in cerebral cortex+++GO:0048675///axon extension+++GO:0043113///receptor clustering+++GO:0006468///protein phosphorylation+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0001764///neuron migration+++GO:0021549///cerebellum development+++GO:1903421///regulation of synaptic vesicle recycling+++GO:0001963///synaptic transmission, dopaminergic+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0016477///cell migration+++GO:0030517///negative regulation of axon extension+++GO:0048511///rhythmic process+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0007416///synapse assembly+++GO:0016310///phosphorylation","cyclin dependent kinase 5","[CDK5_HUMAN|Reviewed]RecName: Full=Cyclin-dependent-like kinase 5; EC=2.7.11.1; AltName: Full=Cell division protein kinase 5; AltName: Full=Serine/threonine-protein kinase PSSALRE; AltName: Full=Tau protein kinase II catalytic subunit; Short=TPKII catalytic subunit;+++[A0A090N7W4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 {ECO:0000313|EMBL:EAL24498.1}; SubName: Full=Cyclin-dependent kinase 5 isoform 1 {ECO:0000313|EMBL:ALQ33426.1}; SubName: Full=Cyclin-dependent kinase 5, isoform CRA_a {ECO:0000313|EMBL:EAW54049.1};+++[A0A0S2Z355_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 isoform 2 {ECO:0000313|EMBL:ALQ33427.1}; Flags: Fragment;+++[Q6IAW3_HUMAN|Unreviewed]SubName: Full=CDK5 protein {ECO:0000313|EMBL:CAG33322.1};"]
[10200,"'MPHOSPH6'",123,87,113,107.666666666667,"03018///RNA degradation",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0000178///exosome (RNase complex)+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0030165///PDZ domain binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0000460///maturation of 5.8S rRNA+++GO:0065003///protein-containing complex assembly","M-phase phosphoprotein 6","[MPH6_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 6 {ECO:0000305};+++[H3BNK8_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6, isoform CRA_b {ECO:0000313|EMBL:EAW95517.1};+++[H3BNT4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000454996};+++[H3BSB3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000456626};+++[H3BU96_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000457537};"]
[10201,"'NME6'",304.16,269.27,272.24,281.89,"04016///MAPK signaling pathway - plant+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00230///Purine metabolism",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase   ATP + dCDP <=> ADP + dCTP+++R00124///ATP:ADP phosphatransferase   ATP + ADP <=> ADP + ATP+++R00156///ATP:UDP phosphotransferase   ATP + UDP <=> ADP + UTP+++R00330///ATP:GDP phosphotransferase   ATP + GDP <=> ADP + GTP+++R01857///ATP:dGDP phosphotransferase   ATP + dGDP <=> ADP + dGTP+++R00570///ATP:CDP phosphotransferase   ATP + CDP <=> ADP + CTP+++R11895///ATP:5-fluorodeoxyuridine-diphosphate phosphotransferase   ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate+++R01137///ATP:dADP phosphotransferase   ATP + dADP <=> ADP + dATP+++R02331///ATP:dUDP phosphotransferase   ATP + dUDP <=> ADP + dUTP+++R02093///ATP:dTDP phosphotransferase   ATP + dTDP <=> ADP + dTTP+++R00139///ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase   2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP+++R00722///ATP:IDP phosphotransferase   ATP + IDP <=> ADP + ITP+++R11894///ATP:5-fluorouridine-diphosphate phosphotransferase   ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate+++R03530///ATP:dIDP phosphotransferase   ATP + dIDP <=> ADP + dITP","GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0045839///negative regulation of mitotic nuclear division+++GO:0016310///phosphorylation+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0030308///negative regulation of cell growth+++GO:0006228///UTP biosynthetic process+++GO:0006915///apoptotic process","NME/NM23 nucleoside diphosphate kinase 6","[NDK6_HUMAN|Reviewed]RecName: Full=Nucleoside diphosphate kinase 6; Short=NDK 6; Short=NDP kinase 6; EC=2.7.4.6; AltName: Full=Inhibitor of p53-induced apoptosis-alpha; Short=IPIA-alpha; AltName: Full=nm23-H6;+++[A0A0C4DG91_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y547_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y7V2_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[C9J1J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000392715}; Flags: Fragment;+++[C9J867_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000405755}; Flags: Fragment;+++[C9J9V6_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013}; Flags: Fragment;+++[C9JQB1_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[F2Z2J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000410435};"]
[10202,"'DHRS2'",14,7,11,10.6666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix","GO:0016491///oxidoreductase activity+++GO:0004090///carbonyl reductase (NADPH) activity+++GO:0005515///protein binding","GO:0008285///negative regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0009636///response to toxic substance+++GO:0055114///oxidation-reduction process+++GO:0043011///myeloid dendritic cell differentiation+++GO:0034599///cellular response to oxidative stress","dehydrogenase/reductase 2","[DHRS2_HUMAN|Reviewed]RecName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial; EC=1.1.1.-; AltName: Full=Dicarbonyl reductase HEP27; AltName: Full=Protein D; AltName: Full=Short chain dehydrogenase/reductase family 25C member 1; Flags: Precursor;+++[C9JZP6_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000401213}; Flags: Fragment;+++[H0YJG9_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451485}; Flags: Fragment;+++[H0YJP4_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451895}; Flags: Fragment;"]
[10203,"'CALCRL'",1,3,1,1.66666666666667,"04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:1990406///CGRP receptor complex+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:1903143///adrenomedullin receptor complex","GO:1990409///adrenomedullin binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0004930///G protein-coupled receptor activity+++GO:0001605///adrenomedullin receptor activity+++GO:0004948///calcitonin receptor activity","GO:0045986///negative regulation of smooth muscle contraction+++GO:0007507///heart development+++GO:0001525///angiogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0031623///receptor internalization+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0006816///calcium ion transport+++GO:0015031///protein transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway+++GO:0071329///cellular response to sucrose stimulus+++GO:0050728///negative regulation of inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","calcitonin receptor like receptor","[CALRL_HUMAN|Reviewed]RecName: Full=Calcitonin gene-related peptide type 1 receptor; Short=CGRP type 1 receptor; AltName: Full=Calcitonin receptor-like receptor; Flags: Precursor;+++[B8ZZJ4_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000386599}; Flags: Fragment;+++[D3DPG9_HUMAN|Unreviewed]SubName: Full=Calcitonin receptor-like, isoform CRA_a {ECO:0000313|EMBL:EAX10926.1};+++[E7EN01_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000415626}; Flags: Fragment;"]
[10204,"'NUTF2'",2383,2909,2908,2733.33333333333,{"$nulls":4},"GO:0044613///nuclear pore central transport channel+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0005637///nuclear inner membrane+++GO:0005643///nuclear pore+++GO:0005640///nuclear outer membrane","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0017056///structural constituent of nuclear pore","GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0042307///positive regulation of protein import into nucleus+++GO:0090204///protein localization to nuclear pore+++GO:1904046///negative regulation of vascular endothelial growth factor production+++GO:0015031///protein transport+++GO:0000060///protein import into nucleus, translocation+++GO:0006913///nucleocytoplasmic transport","nuclear transport factor 2","[NTF2_HUMAN|Reviewed]RecName: Full=Nuclear transport factor 2 {ECO:0000303|PubMed:7744965}; Short=NTF-2; AltName: Full=Placental protein 15 {ECO:0000303|PubMed:3380696}; Short=PP15 {ECO:0000303|PubMed:3380696};+++[A0A024R6Y2_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2, isoform CRA_a {ECO:0000313|EMBL:EAW83182.1};+++[H3BRV9_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2 {ECO:0000313|Ensembl:ENSP00000456428}; Flags: Fragment;"]
[10205,"'MPZL2'",43,15,13,23.6666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0009653///anatomical structure morphogenesis+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","myelin protein zero like 2","[MPZL2_HUMAN|Reviewed]RecName: Full=Myelin protein zero-like protein 2; AltName: Full=Epithelial V-like antigen 1; Flags: Precursor;+++[A0A024R3K1_HUMAN|Unreviewed]SubName: Full=Epithelial V-like antigen 1, isoform CRA_a {ECO:0000313|EMBL:EAW67359.1};"]
[10206,"'TRIM13'",220,196,201.76,205.92,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0005737///cytoplasm+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:1902187///negative regulation of viral release from host cell+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0010332///response to gamma radiation+++GO:0016239///positive regulation of macroautophagy+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0002376///immune system process+++GO:0051865///protein autoubiquitination+++GO:0009653///anatomical structure morphogenesis+++GO:0010942///positive regulation of cell death+++GO:0016567///protein ubiquitination+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0045087///innate immune response+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:0032897///negative regulation of viral transcription","tripartite motif containing 13","[TRI13_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM13; EC=2.3.2.27; AltName: Full=B-cell chronic lymphocytic leukemia tumor suppressor Leu5; AltName: Full=Leukemia-associated protein 5; AltName: Full=Putative tumor suppressor RFP2; AltName: Full=RING finger protein 77; AltName: Full=RING-type E3 ubiquitin transferase TRIM13 {ECO:0000305}; AltName: Full=Ret finger protein 2; AltName: Full=Tripartite motif-containing protein 13;+++[A0A024RDU3_HUMAN|Unreviewed]SubName: Full=Ret finger protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX08848.1};+++[A0A184AP76_HUMAN|Unreviewed]SubName: Full=Putative tumor suppressor RFP2 {ECO:0000313|EMBL:ABE41638.1};+++[L7MTJ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAD38633.1}; Flags: Fragment;+++[L8E9D0_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM13 {ECO:0000313|EMBL:CCQ43336.1};+++[X6R9U5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000367425}; Flags: Fragment;+++[X6RH27_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000404586}; Flags: Fragment;"]
[10207,"'PATJ'",278.85,302.09,244,274.98,"04390///Hippo signaling pathway+++05165///Human papillomavirus infection+++04530///Tight junction",{"$nulls":3},"GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0045177///apical part of cell+++GO:0032991///protein-containing complex+++GO:0005923///bicellular tight junction+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0035556///intracellular signal transduction+++GO:0070830///bicellular tight junction assembly","PATJ, crumbs cell polarity complex component","[INADL_HUMAN|Reviewed]RecName: Full=InaD-like protein; Short=Inadl protein; Short=hINADL; AltName: Full=Pals1-associated tight junction protein; AltName: Full=Protein associated to tight junctions;+++[A0A087WUZ6_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000479041};+++[A0A0U1RQR3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489130}; Flags: Fragment;+++[A0A0U1RQT2_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489159};+++[A0A0U1RQW4_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489200}; Flags: Fragment;+++[A0A0U1RR46_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489335};+++[A0A0U1RRD7_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489475}; Flags: Fragment;+++[A0A0X1KG69_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000326199};+++[A0A2R8Y549_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494277};+++[A0A2R8Y5I3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494824};+++[A5PKX9_HUMAN|Unreviewed]SubName: Full=INADL protein {ECO:0000313|EMBL:AAI42662.1};+++[B4DE90_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59473, highly similar to InaD-like protein {ECO:0000313|EMBL:BAG57001.1};"]
[10208,"'USPL1'",188,177,170,178.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0070140///SUMO-specific isopeptidase activity+++GO:0043130///ubiquitin binding","GO:0030576///Cajal body organization+++GO:0009301///snRNA transcription+++GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0008283///cell proliferation","ubiquitin specific peptidase like 1","[USPL1_HUMAN|Reviewed]RecName: Full=SUMO-specific isopeptidase USPL1; EC=3.4.22.-; AltName: Full=Ubiquitin-specific peptidase-like protein 1; Short=USP-like 1;+++[A8K1B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75211, highly similar to Homo sapiens ubiquitin specific peptidase like 1, mRNA {ECO:0000313|EMBL:BAF82515.1};+++[B3KQ64_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32952 fis, clone TESTI2008081, highly similar to Homo sapiens D13S106 a highly charged amino acid sequence {ECO:0000313|EMBL:BAG51926.1}; Flags: Fragment;+++[L8ECC7_HUMAN|Unreviewed]SubName: Full=Alternative protein USPL1 {ECO:0000313|EMBL:CCQ43337.1};"]
[10209,"'EIF1'",2408,2606,2985,2666.33333333333,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding","GO:0006412///translation+++GO:0006446///regulation of translational initiation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0006413///translational initiation","eukaryotic translation initiation factor 1","[EIF1_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1; Short=eIF1; AltName: Full=A121; AltName: Full=Protein translation factor SUI1 homolog; AltName: Full=Sui1iso1;+++[K7EM18_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000466321};+++[K7EQP2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000467918}; Flags: Fragment;+++[Q6IAV3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW60754.1}; SubName: Full=Putative translation initiation factor {ECO:0000313|EMBL:AAP35291.1}; SubName: Full=SUI1 protein {ECO:0000313|EMBL:CAG33332.1}; SubName: Full=cDNA, FLJ92128, Homo sapiens putative translation initiation factor (SUI1), mRNA {ECO:0000313|EMBL:BAG34803.1};"]
[1021,"'CDK6'",2331,1885,1431,1882.33333333333,"05218///Melanoma+++05224///Breast cancer+++04110///Cell cycle+++05200///Pathways in cancer+++05214///Glioma+++04218///Cellular senescence+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05162///Measles+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04151///PI3K-Akt signaling pathway+++05223///Non-small cell lung cancer+++05163///Human cytomegalovirus infection+++04934///Cushing's syndrome+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++05161///Hepatitis B+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++05212///Pancreatic cancer","H00269///Primary microcephaly (MCPH)","M00692///Cell cycle - G1/S transition",null,"GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0001726///ruffle+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0098770///FBXO family protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0030332///cyclin binding+++GO:0016740///transferase activity","GO:0050680///negative regulation of epithelial cell proliferation+++GO:0043697///cell dedifferentiation+++GO:0007049///cell cycle+++GO:0048699///generation of neurons+++GO:0045668///negative regulation of osteoblast differentiation+++GO:2000145///regulation of cell motility+++GO:0045656///negative regulation of monocyte differentiation+++GO:0014002///astrocyte development+++GO:0003323///type B pancreatic cell development+++GO:0009615///response to virus+++GO:0051301///cell division+++GO:0042063///gliogenesis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0021670///lateral ventricle development+++GO:0045596///negative regulation of cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0006468///protein phosphorylation+++GO:0045646///regulation of erythrocyte differentiation+++GO:0030154///cell differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0021542///dentate gyrus development+++GO:0010468///regulation of gene expression+++GO:0045786///negative regulation of cell cycle+++GO:0007050///cell cycle arrest","cyclin dependent kinase 6","[CDK6_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 6; EC=2.7.11.22; AltName: Full=Cell division protein kinase 6; AltName: Full=Serine/threonine-protein kinase PLSTIRE;"]
[10210,"'TOPORS'",530,503,414,482.333333333333,null,"H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005814///centriole+++GO:0000151///ubiquitin ligase complex+++GO:0000930///gamma-tubulin complex+++GO:0030496///midbody+++GO:0032391///photoreceptor connecting cilium+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005868///cytoplasmic dynein complex+++GO:0036064///ciliary basal body+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0019789///SUMO transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0044547///DNA topoisomerase binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003823///antigen binding","GO:0000209///protein polyubiquitination+++GO:0034504///protein localization to nucleus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006351///transcription, DNA-templated+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0042127///regulation of cell proliferation+++GO:0016925///protein sumoylation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0010842///retina layer formation+++GO:0046548///retinal rod cell development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0035845///photoreceptor cell outer segment organization+++GO:0051457///maintenance of protein location in nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0046549///retinal cone cell development+++GO:0006513///protein monoubiquitination","TOP1 binding arginine/serine rich protein","[TOPRS_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Topors; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase Topors {ECO:0000305}; AltName: Full=SUMO1-protein E3 ligase Topors; AltName: Full=Topoisomerase I-binding RING finger protein; AltName: Full=Topoisomerase I-binding arginine/serine-rich protein; AltName: Full=Tumor suppressor p53-binding protein 3; Short=p53-binding protein 3; Short=p53BP3;"]
[10211,"'FLOT1'",1192,1079,1181,1150.66666666667,"04910///Insulin signaling pathway",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0044853///plasma membrane raft+++GO:0042383///sarcolemma+++GO:0016600///flotillin complex+++GO:0005815///microtubule organizing center+++GO:0048786///presynaptic active zone+++GO:0005765///lysosomal membrane+++GO:0098793///presynapse+++GO:0042470///melanosome+++GO:0030027///lamellipodium+++GO:0005768///endosome+++GO:0045121///membrane raft+++GO:0005913///cell-cell adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0044291///cell-cell contact zone+++GO:0098978///glutamatergic synapse+++GO:0005901///caveola+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0001931///uropod+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0098982///GABA-ergic synapse+++GO:0016324///apical plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0008180///COP9 signalosome+++GO:0098691///dopaminergic synapse+++GO:0034451///centriolar satellite+++GO:0030864///cortical actin cytoskeleton+++GO:0005769///early endosome","GO:0046982///protein heterodimerization activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0002020///protease binding+++GO:0005515///protein binding","GO:1903044///protein localization to membrane raft+++GO:0032728///positive regulation of interferon-beta production+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0001765///membrane raft assembly+++GO:1901890///positive regulation of cell junction assembly+++GO:0022617///extracellular matrix disassembly+++GO:0051580///regulation of neurotransmitter uptake+++GO:0070528///protein kinase C signaling+++GO:0007409///axonogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0050821///protein stabilization+++GO:1901741///positive regulation of myoblast fusion+++GO:0051260///protein homooligomerization+++GO:0044854///plasma membrane raft assembly+++GO:0034976///response to endoplasmic reticulum stress+++GO:0033227///dsRNA transport+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0002090///regulation of receptor internalization+++GO:0045807///positive regulation of endocytosis+++GO:0035023///regulation of Rho protein signal transduction+++GO:0001819///positive regulation of cytokine production+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034143///regulation of toll-like receptor 4 signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071360///cellular response to exogenous dsRNA+++GO:0032226///positive regulation of synaptic transmission, dopaminergic","flotillin 1","[FLOT1_HUMAN|Reviewed]RecName: Full=Flotillin-1;+++[A0A0G2JJQ6_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000409995}; Flags: Fragment;+++[A0A140T905_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388153}; Flags: Fragment;+++[A0A140T907_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388104}; Flags: Fragment;+++[A0A140T910_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388517}; Flags: Fragment;+++[A0A140T957_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393145}; Flags: Fragment;+++[A0A140T959_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000392736}; Flags: Fragment;+++[A0A140T974_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393767}; Flags: Fragment;+++[A0A140T9B1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000397108}; Flags: Fragment;+++[A0A140T9C3_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398866}; Flags: Fragment;+++[A0A140T9H7_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000403574}; Flags: Fragment;+++[A0A140T9L9_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000407101}; Flags: Fragment;+++[A0A140T9R1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000410658}; Flags: Fragment;+++[A0A140T9W4_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415215}; Flags: Fragment;+++[A0A140T9X0_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415104}; Flags: Fragment;+++[A2AB09_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000395333}; Flags: Fragment;+++[A2AB10_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000400615}; Flags: Fragment;+++[A2AB11_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000412058}; Flags: Fragment;+++[A2AB12_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398834}; Flags: Fragment;+++[A2AB13_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000391341}; Flags: Fragment;+++[A2ABJ5_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000404300}; Flags: Fragment;+++[A2VCL5_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:AAI28155.1}; Flags: Fragment;+++[Q5ST80_HUMAN|Unreviewed]SubName: Full=FLOT1 {ECO:0000313|EMBL:AQY76816.1}; SubName: Full=FLOT1 protein {ECO:0000313|EMBL:BAF31269.1}; SubName: Full=Flotillin 1 {ECO:0000313|EMBL:AAP35740.1}; SubName: Full=Flotillin 1, isoform CRA_b {ECO:0000313|EMBL:EAX03326.1};+++[Q6IB58_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:CAG33227.1};"]
[10212,"'DDX39A'",283,272,295,283.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing","DExD-box helicase 39A","[DX39A_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX39A; EC=3.6.4.13; AltName: Full=DEAD box protein 39; AltName: Full=Nuclear RNA helicase URH49;+++[A0A024R7H0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, isoform CRA_b {ECO:0000313|EMBL:EAW84416.1};+++[A0A0D9SEM9_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000485838}; Flags: Fragment;+++[K7EIL8_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000464801}; Flags: Fragment;+++[K7EL56_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000465926}; Flags: Fragment;+++[K7EN69_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000466810}; Flags: Fragment;+++[K7ENP6_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467040}; Flags: Fragment;+++[K7EPJ3_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467411}; Flags: Fragment;+++[K7EQN7_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467911}; Flags: Fragment;"]
[10213,"'PSMD14'",485,470,398,451,"05169///Epstein-Barr virus infection+++03050///Proteasome",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0031597///cytosolic proteasome complex+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0000502///proteasome complex+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0034774///secretory granule lumen+++GO:0005634///nucleus+++GO:0022624///proteasome accessory complex+++GO:1904813///ficolin-1-rich granule lumen","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0061133///endopeptidase activator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070628///proteasome binding+++GO:0016787///hydrolase activity","GO:0006281///DNA repair+++GO:0043312///neutrophil degranulation+++GO:0070536///protein K63-linked deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010950///positive regulation of endopeptidase activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006508///proteolysis+++GO:0000724///double-strand break repair via homologous recombination+++GO:0043687///post-translational protein modification+++GO:0045471///response to ethanol+++GO:0016579///protein deubiquitination+++GO:0061136///regulation of proteasomal protein catabolic process","proteasome 26S subunit, non-ATPase 14","[PSDE_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 14; EC=3.4.19.-; AltName: Full=26S proteasome regulatory subunit RPN11; AltName: Full=26S proteasome-associated PAD1 homolog 1;+++[A0A140VKF2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 69n {ECO:0000313|EMBL:AEE61289.1};+++[C9JW37_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 14 {ECO:0000313|Ensembl:ENSP00000399311}; Flags: Fragment;+++[Q4ZG77_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAX88940.1}; Flags: Fragment;+++[Q53TH1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAY15016.1}; Flags: Fragment;"]
[10215,"'OLIG2'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046983///protein dimerization activity+++GO:0071837///HMG box domain binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity","GO:0021522///spinal cord motor neuron differentiation+++GO:0007399///nervous system development+++GO:0021794///thalamus development+++GO:0045665///negative regulation of neuron differentiation+++GO:0048663///neuron fate commitment+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0021530///spinal cord oligodendrocyte cell fate specification+++GO:0042552///myelination+++GO:0030182///neuron differentiation+++GO:0021529///spinal cord oligodendrocyte cell differentiation+++GO:0048709///oligodendrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0021778///oligodendrocyte cell fate specification+++GO:0007275///multicellular organism development","oligodendrocyte transcription factor 2","[OLIG2_HUMAN|Reviewed]RecName: Full=Oligodendrocyte transcription factor 2; Short=Oligo2; AltName: Full=Class B basic helix-loop-helix protein 1; Short=bHLHb1; AltName: Full=Class E basic helix-loop-helix protein 19; Short=bHLHe19; AltName: Full=Protein kinase C-binding protein 2; AltName: Full=Protein kinase C-binding protein RACK17;+++[C9J444_HUMAN|Unreviewed]SubName: Full=Oligodendrocyte transcription factor 2 {ECO:0000313|Ensembl:ENSP00000391183}; Flags: Fragment;"]
[102157402,"'AK6'",69.69,64.72,77.69,70.7,"00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03008///Ribosome biogenesis in eukaryotes",null,"M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R00127///ATP:AMP phosphotransferase   ATP + AMP <=> 2 ADP+++R01547///ATP:dAMP phosphotransferase   ATP + dAMP <=> ADP + dADP","GO:0000790///nuclear chromatin+++GO:0005669///transcription factor TFIID complex+++GO:0031389///Rad17 RFC-like complex+++GO:0005737///cytoplasm+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000125///PCAF complex+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003713///transcription coactivator activity+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005524///ATP binding+++GO:0033613///activating transcription factor binding+++GO:0051117///ATPase binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0003689///DNA clamp loader activity+++GO:0003682///chromatin binding+++GO:0050145///nucleoside monophosphate kinase activity+++GO:0004017///adenylate kinase activity+++GO:0016887///ATPase activity","GO:0030307///positive regulation of cell growth+++GO:0043966///histone H3 acetylation+++GO:0033314///mitotic DNA replication checkpoint+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008156///negative regulation of DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000492///box C/D snoRNP assembly+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0000077///DNA damage checkpoint+++GO:0006366///transcription by RNA polymerase II+++GO:0042325///regulation of phosphorylation+++GO:0050821///protein stabilization+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0070555///response to interleukin-1+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0043066///negative regulation of apoptotic process+++GO:0006260///DNA replication+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0000076///DNA replication checkpoint+++GO:0007093///mitotic cell cycle checkpoint","adenylate kinase 6","[KAD6_HUMAN|Reviewed]RecName: Full=Adenylate kinase isoenzyme 6 {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK6 {ECO:0000255|HAMAP-Rule:MF_03173}; EC=2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03173}; AltName: Full=Adrenal gland protein AD-004; AltName: Full=Coilin-interacting nuclear ATPase protein {ECO:0000255|HAMAP-Rule:MF_03173}; Short=hCINAP; AltName: Full=Dual activity adenylate kinase/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK/ATPase {ECO:0000255|HAMAP-Rule:MF_03173};+++[A0A087WVD7_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000479366};+++[A0A087WY94_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000481620};+++[D6RDH4_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000420947};"]
[10217,"'CTDSPL'",498,375,400,424.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0016787///hydrolase activity","GO:0016311///dephosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0008150///biological_process","CTD small phosphatase like","[CTDSL_HUMAN|Reviewed]RecName: Full=CTD small phosphatase-like protein; Short=CTDSP-like; EC=3.1.3.16; AltName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; AltName: Full=NIF-like protein; AltName: Full=Nuclear LIM interactor-interacting factor 1; Short=NLI-interacting factor 1; AltName: Full=Protein YA22; Short=hYA22; AltName: Full=RBSP3; AltName: Full=Small C-terminal domain phosphatase 3; Short=SCP3; Short=Small CTD phosphatase 3;+++[A0A024R2L8_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, isoform CRA_c {ECO:0000313|EMBL:EAW64505.1};+++[F8WED2_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000408183};+++[H7C2B9_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000404977}; Flags: Fragment;+++[H7C2S4_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000407443}; Flags: Fragment;+++[H7C353_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000409600}; Flags: Fragment;"]
[10218,"'ANGPTL7'",1082,1314,1119,1171.66666666667,{"$nulls":4},"GO:0005576///extracellular region","GO:0005515///protein binding","GO:0006979///response to oxidative stress","angiopoietin like 7","[ANGL7_HUMAN|Reviewed]RecName: Full=Angiopoietin-related protein 7; AltName: Full=Angiopoietin-like factor; AltName: Full=Angiopoietin-like protein 7; AltName: Full=Cornea-derived transcript 6 protein; Flags: Precursor;"]
[10219,"'KLRG1'",2,1,4,2.33333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0030246///carbohydrate binding+++GO:0042803///protein homodimerization activity+++GO:0038023///signaling receptor activity","GO:0007263///nitric oxide mediated signal transduction+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045087///innate immune response+++GO:0002376///immune system process+++GO:0009749///response to glucose+++GO:0007166///cell surface receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006968///cellular defense response+++GO:0006954///inflammatory response+++GO:0030073///insulin secretion","killer cell lectin like receptor G1","[KLRG1_HUMAN|Reviewed]RecName: Full=Killer cell lectin-like receptor subfamily G member 1; AltName: Full=C-type lectin domain family 15 member A; AltName: Full=ITIM-containing receptor MAFA-L; AltName: Full=MAFA-like receptor; AltName: Full=Mast cell function-associated antigen;+++[F5H207_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily G member 1 {ECO:0000313|Ensembl:ENSP00000445627}; Flags: Fragment;+++[F5H8E3_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily G member 1 {ECO:0000313|Ensembl:ENSP00000443658}; Flags: Fragment;"]
[1022,"'CDK7'",207,236,259,234,"04110///Cell cycle+++03022///Basal transcription factors+++03420///Nucleotide excision repair",null,"M00290///Holo-TFIIH complex",null,"GO:0070985///transcription factor TFIIK complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0003713///transcription coactivator activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0050681///androgen receptor binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008022///protein C-terminus binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0007050///cell cycle arrest+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007049///cell cycle+++GO:0030521///androgen receptor signaling pathway+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0008283///cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0050821///protein stabilization+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006370///7-methylguanosine mRNA capping+++GO:0006468///protein phosphorylation+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016310///phosphorylation+++GO:0006363///termination of RNA polymerase I transcription","cyclin dependent kinase 7","[CDK7_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 7; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=39 kDa protein kinase; Short=p39 Mo15; AltName: Full=CDK-activating kinase 1; AltName: Full=Cell division protein kinase 7; AltName: Full=Serine/threonine-protein kinase 1; AltName: Full=TFIIH basal transcription factor complex kinase subunit;+++[A0A0S2Z3F9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), isoform CRA_a {ECO:0000313|EMBL:EAW51300.1}; SubName: Full=Cyclin-dependent kinase 7 isoform 1 {ECO:0000313|EMBL:ALQ33428.1}; Flags: Fragment;+++[D6R9G1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422121};+++[D6R9Z2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422027};+++[D6RAD4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422737};+++[D6REC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425043}; Flags: Fragment;+++[D6RF14_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000421559};+++[D6RFL0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 isoform 3 {ECO:0000313|EMBL:ALQ33429.1};+++[D6RGG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000426372};+++[D6RI01_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425983};+++[D6RIG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425893};+++[Q14495_HUMAN|Unreviewed]SubName: Full=Protein kinase {ECO:0000313|EMBL:CAA53766.1}; Flags: Fragment;"]
[10220,"'GDF11'",2912,2066,2174,2384,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005575///cellular_component+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity","GO:0060021///roof of mouth development+++GO:0007399///nervous system development+++GO:0048593///camera-type eye morphogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0048468///cell development+++GO:0008285///negative regulation of cell proliferation+++GO:0060395///SMAD protein signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010469///regulation of signaling receptor activity+++GO:0043408///regulation of MAPK cascade+++GO:0001501///skeletal system development+++GO:0031016///pancreas development+++GO:0007498///mesoderm development+++GO:0001656///metanephros development+++GO:0021512///spinal cord anterior/posterior patterning+++GO:0048469///cell maturation+++GO:0042981///regulation of apoptotic process+++GO:0009887///animal organ morphogenesis+++GO:0001657///ureteric bud development+++GO:0009952///anterior/posterior pattern specification+++GO:0045596///negative regulation of cell differentiation","growth differentiation factor 11","[GDF11_HUMAN|Reviewed]RecName: Full=Growth/differentiation factor 11 {ECO:0000303|PubMed:10391213}; Short=GDF-11; AltName: Full=Bone morphogenetic protein 11 {ECO:0000303|PubMed:10075854}; Short=BMP-11; Flags: Precursor;+++[A0A024RB20_HUMAN|Unreviewed]SubName: Full=Growth differentiation factor 11, isoform CRA_a {ECO:0000313|EMBL:EAW96831.1};+++[H0YI30_HUMAN|Unreviewed]SubName: Full=Growth/differentiation factor 11 {ECO:0000313|Ensembl:ENSP00000448390}; Flags: Fragment;"]
[10221,"'TRIB1'",555,410,445,470,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004860///protein kinase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0055106///ubiquitin-protein transferase regulator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0005524///ATP binding","GO:0006469///negative regulation of protein kinase activity+++GO:0006468///protein phosphorylation+++GO:0045659///negative regulation of neutrophil differentiation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043405///regulation of MAP kinase activity+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0007254///JNK cascade+++GO:0032496///response to lipopolysaccharide+++GO:0045645///positive regulation of eosinophil differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0045651///positive regulation of macrophage differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation","tribbles pseudokinase 1","[TRIB1_HUMAN|Reviewed]RecName: Full=Tribbles homolog 1; Short=TRB-1; AltName: Full=G-protein-coupled receptor-induced gene 2 protein; Short=GIG-2; AltName: Full=SKIP1;+++[E5RFH4_HUMAN|Unreviewed]SubName: Full=Tribbles homolog 1 {ECO:0000313|Ensembl:ENSP00000428879};"]
[10223,"'GPA33'",1,5,9,5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0038023///signaling receptor activity",null,"glycoprotein A33","[GPA33_HUMAN|Reviewed]RecName: Full=Cell surface A33 antigen; AltName: Full=Glycoprotein A33; Flags: Precursor;+++[A0A0J9YXH7_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000488407}; Flags: Fragment;+++[E9PMB2_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000431195};"]
[10224,"'ZNF443'",11,20.5,7,12.8333333333333,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 443","[ZN443_HUMAN|Reviewed]RecName: Full=Zinc finger protein 443; AltName: Full=Krueppel-type zinc finger protein ZK1;+++[F8WDY2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 443 {ECO:0000313|Ensembl:ENSP00000389105};"]
[10225,"'CD96'",10.06,6.16,4.55,6.92333333333333,null,"H01008///C syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm+++GO:0005912///adherens junction+++GO:0005886///plasma membrane",null,"GO:0007160///cell-matrix adhesion+++GO:0002728///negative regulation of natural killer cell cytokine production+++GO:0006955///immune response+++GO:0032496///response to lipopolysaccharide+++GO:0002534///cytokine production involved in inflammatory response+++GO:0007155///cell adhesion+++GO:0032689///negative regulation of interferon-gamma production+++GO:0050776///regulation of immune response","CD96 molecule","[TACT_HUMAN|Reviewed]RecName: Full=T-cell surface protein tactile; AltName: Full=Cell surface antigen CD96; AltName: Full=T cell-activated increased late expression protein; AltName: CD_antigen=CD96; Flags: Precursor;+++[E9PEJ1_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417152};+++[F8WDV3_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417680};+++[H7C4F0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417150}; Flags: Fragment;+++[L8EAH0_HUMAN|Unreviewed]SubName: Full=Alternative protein CD96 {ECO:0000313|EMBL:CCQ43338.1};+++[Q8WUE2_HUMAN|Unreviewed]SubName: Full=CD96 antigen, isoform CRA_b {ECO:0000313|EMBL:EAW79697.1}; SubName: Full=CD96 protein {ECO:0000313|EMBL:AAH20749.1}; SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000389801};+++[U3KPT0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000475194}; Flags: Fragment;"]
[10226,"'PLIN3'",1127,1315.02,1344,1262.00666666667,{"$nulls":4},"GO:0010008///endosome membrane+++GO:0030133///transport vesicle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005768///endosome","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0016192///vesicle-mediated transport","perilipin 3","[PLIN3_HUMAN|Reviewed]RecName: Full=Perilipin-3; AltName: Full=47 kDa mannose 6-phosphate receptor-binding protein; Short=47 kDa MPR-binding protein; AltName: Full=Cargo selection protein TIP47; AltName: Full=Mannose-6-phosphate receptor-binding protein 1; AltName: Full=Placental protein 17; Short=PP17;+++[A0A140VJN8_HUMAN|Unreviewed]RecName: Full=Perilipin {ECO:0000256|PIRNR:PIRNR036881};+++[K7EJD0_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465117}; Flags: Fragment;+++[K7EL96_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465975}; Flags: Fragment;+++[K7ER39_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468096}; Flags: Fragment;+++[K7ERZ3_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468476}; Flags: Fragment;"]
[10227,"'MFSD10'",1273,1783,1997,1684.33333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016021///integral component of membrane","GO:0008514///organic anion transmembrane transporter activity+++GO:0008493///tetracycline transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006915///apoptotic process+++GO:0043252///sodium-independent organic anion transport+++GO:0015904///tetracycline transport","major facilitator superfamily domain containing 10","[MFS10_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 10; AltName: Full=Tetracycline transporter-like protein;+++[D6R9N3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423509};+++[D6RA47_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423402};+++[D6RE79_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000426907};+++[D6RHV1_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000427637};+++[D6RIZ4_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000425757};"]
[10228,"'STX6'",505,559,476,513.333333333333,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0000139///Golgi membrane+++GO:0005769///early endosome+++GO:0030136///clathrin-coated vesicle+++GO:0005654///nucleoplasm+++GO:0032588///trans-Golgi network membrane+++GO:0045335///phagocytic vesicle+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0008021///synaptic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0031201///SNARE complex","GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0016192///vesicle-mediated transport+++GO:0032880///regulation of protein localization+++GO:0048278///vesicle docking+++GO:0032456///endocytic recycling+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0006906///vesicle fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048193///Golgi vesicle transport+++GO:0090161///Golgi ribbon formation+++GO:0007032///endosome organization+++GO:1903827///regulation of cellular protein localization+++GO:0016189///synaptic vesicle to endosome fusion","syntaxin 6","[STX6_HUMAN|Reviewed]RecName: Full=Syntaxin-6;"]
[102288414,"'C11orf98'",434.4,522.39,564.93,507.24,{"$nulls":7},"chromosome 11 open reading frame 98","[CK098_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf98 {ECO:0000305};+++[A0A0B4J220_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 48, isoform CRA_c {ECO:0000313|EMBL:EAW74054.1};+++[L0R588_HUMAN|Unreviewed]SubName: Full=Alternative protein C11orf48 {ECO:0000313|EMBL:CCO13689.1};"]
[10229,"'COQ7'",231.01,196,188,205.003333333333,"01100///Metabolic pathways+++00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01110///Biosynthesis of secondary metabolites","H00999///Coenzyme Q10 deficiency","M00128///Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone","R08775///2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O+++R04984///2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O","GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008682///2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity+++GO:0004497///monooxygenase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008340///determination of adult lifespan+++GO:0006744///ubiquinone biosynthetic process+++GO:0042493///response to drug+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0055114///oxidation-reduction process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000377///regulation of reactive oxygen species metabolic process","coenzyme Q7, hydroxylase","[COQ7_HUMAN|Reviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000255|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000255|HAMAP-Rule:MF_03194}; Flags: Precursor;+++[H3BP28_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[H3BS11_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456490};+++[H3BSZ3_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456943}; Flags: Fragment;+++[H3BTN8_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457256}; Flags: Fragment;+++[I3L1T0_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000459076}; SubName: Full=Coenzyme Q7 homolog, ubiquinone (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW50269.1};+++[Q49A71_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[Q8NI45_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};"]
[10231,"'RCAN2'",572,608,588,589.333333333333,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity+++GO:0005515///protein binding","GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0019722///calcium-mediated signaling","regulator of calcineurin 2","[RCAN2_HUMAN|Reviewed]RecName: Full=Calcipressin-2; AltName: Full=Down syndrome candidate region 1-like 1; AltName: Full=Myocyte-enriched calcineurin-interacting protein 2; Short=MCIP2; AltName: Full=Regulator of calcineurin 2; AltName: Full=Thyroid hormone-responsive protein ZAKI-4;+++[A0A0A0MSB6_HUMAN|Unreviewed]SubName: Full=Calcipressin-2 {ECO:0000313|Ensembl:ENSP00000384317};+++[A8MXP8_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000378347};+++[B2R612_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92723, highly similar to Homo sapiens Down syndrome critical region gene 1-like 1 (DSCR1L1), mRNA {ECO:0000313|EMBL:BAG35309.1};+++[H0YL43_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000453052}; Flags: Fragment;+++[L0R6N1_HUMAN|Unreviewed]SubName: Full=Alternative protein RCAN2 {ECO:0000313|EMBL:CCO13800.1};+++[L8E7F0_HUMAN|Unreviewed]SubName: Full=Alternative protein RCN2 {ECO:0000313|EMBL:CCQ43195.1};+++[Q86YJ0_HUMAN|Unreviewed]SubName: Full=RCAN2 protein {ECO:0000313|EMBL:AAH38509.1};"]
[10232,"'MSLN'",31,40,42,37.6666666666667,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0044267///cellular protein metabolic process+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0031016///pancreas development+++GO:0043687///post-translational protein modification","mesothelin","[MSLN_HUMAN|Reviewed]RecName: Full=Mesothelin; AltName: Full=CAK1 antigen; AltName: Full=Pre-pro-megakaryocyte-potentiating factor; Contains: RecName: Full=Megakaryocyte-potentiating factor; Short=MPF; Contains: RecName: Full=Mesothelin, cleaved form; Flags: Precursor;+++[H3BMA1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000454295}; Flags: Fragment;+++[H3BR90_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000456132}; Flags: Fragment;+++[H3BUX1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000457847}; Flags: Fragment;+++[H3BV92_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000458003}; Flags: Fragment;"]
[10233,"'LRRC23'",131,112,125,122.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","leucine rich repeat containing 23","[LRC23_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 23; AltName: Full=Leucine-rich protein B7;+++[A8K8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77436, highly similar to Homo sapiens B7 gene (B7), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF85056.1};+++[C9JEW3_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000396049};+++[C9JKE8_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000402554};+++[C9JQN5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000408066}; Flags: Fragment;+++[E9PDZ4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000397192};+++[F2Z299_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000392623};"]
[10234,"'LRRC17'",644,738,778,720,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space",null,"GO:0033687///osteoblast proliferation+++GO:0048539///bone marrow development+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0001649///osteoblast differentiation+++GO:0001503///ossification","leucine rich repeat containing 17","[LRC17_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 17; AltName: Full=p37NB; Flags: Precursor;+++[C9JT74_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 17 {ECO:0000313|Ensembl:ENSP00000394194}; Flags: Fragment;"]
[10235,"'RASGRP2'",18,25,21,21.3333333333333,"04062///Chemokine signaling pathway+++04015///Rap1 signaling pathway+++04010///MAPK signaling pathway+++05200///Pathways in cancer+++04014///Ras signaling pathway+++04611///Platelet activation","H01235///Bleeding disorder platelet-type",null,null,"GO:0043005///neuron projection+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0008289///lipid binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0001558///regulation of cell growth+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0071277///cellular response to calcium ion","RAS guanyl releasing protein 2","[GRP2_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 2; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor I; Short=CalDAG-GEFI; AltName: Full=Cdc25-like protein; Short=hCDC25L; AltName: Full=F25B3.3 kinase-like protein;+++[A6NHE2_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366705}; Flags: Fragment;+++[A6NJ28_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366706};+++[A8MTF9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377950};+++[A8MVK8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377949};+++[B3KV60_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16161 fis, clone BRCAN2012110, highly similar to Homo sapiens RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53672.1};+++[C9JKH6_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000389068}; Flags: Fragment;+++[C9JZ82_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000401314}; Flags: Fragment;+++[E7EM78_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399114}; Flags: Fragment;+++[E7EMB4_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399028};+++[E7EWQ7_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000396029};+++[Q2YDB1_HUMAN|Unreviewed]SubName: Full=RASGRP2 protein {ECO:0000313|EMBL:AAI10307.1}; Flags: Fragment;"]
[10236,"'HNRNPR'",1531,1359,1380,1423.33333333333,{"$nulls":4},"GO:0071013///catalytic step 2 spliceosome+++GO:0005737///cytoplasm+++GO:0043679///axon terminus+++GO:0030426///growth cone+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005681///spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0030425///dendrite","GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0061157///mRNA destabilization+++GO:0043086///negative regulation of catalytic activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process+++GO:0061014///positive regulation of mRNA catabolic process","heterogeneous nuclear ribonucleoprotein R","[HNRPR_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein R; Short=hnRNP R;+++[A0A286YEZ8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|Ensembl:ENSP00000493186}; Flags: Fragment;+++[B4DMB1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53358, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59823.1};+++[B4DMD1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53360, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59843.1};+++[B4DT28_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R, isoform CRA_a {ECO:0000313|EMBL:EAW95040.1}; SubName: Full=cDNA FLJ54544, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG61840.1};+++[Q0VGD6_HUMAN|Unreviewed]SubName: Full=HNRPR protein {ECO:0000313|EMBL:AAI10390.1}; Flags: Fragment;+++[Q6MZS5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686A13234 {ECO:0000313|EMBL:CAE45953.1}; Flags: Fragment;"]
[10237,"'SLC35B1'",489,486,593,522.666666666667,{"$nulls":4},"GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005459///UDP-galactose transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:0008643///carbohydrate transport","solute carrier family 35 member B1","[S35B1_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member B1; AltName: Full=UDP-galactose transporter-related protein 1; Short=UGTrel1; Short=hUGTrel1;+++[D3DTX1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35, member B1, isoform CRA_a {ECO:0000313|EMBL:EAW94669.1};+++[D6R981_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000423323}; Flags: Fragment;+++[D6R9G9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000422104}; Flags: Fragment;+++[D6RB73_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424367}; Flags: Fragment;+++[D6RDY9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000425179};+++[D6RE58_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426961}; Flags: Fragment;+++[D6RF81_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424857}; Flags: Fragment;+++[D6RG34_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426402}; Flags: Fragment;+++[D6RHG0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000427689}; Flags: Fragment;"]
[10238,"'DCAF7'",1835.04,1753.54,1626.51,1738.36333333333,{"$nulls":4},"GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0043687///post-translational protein modification","DDB1 and CUL4 associated factor 7","[DCAF7_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 7; AltName: Full=WD repeat-containing protein 68; AltName: Full=WD repeat-containing protein An11 homolog;+++[A0A087WWI6_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 7 {ECO:0000313|Ensembl:ENSP00000480250}; Flags: Fragment;"]
[10239,"'AP3S2'",375.92,234.54,444.82,351.76,"04142///Lysosome",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0030123///AP-3 adaptor complex+++GO:1904115///axon cytoplasm+++GO:0030117///membrane coat+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus",null,"GO:0048490///anterograde synaptic vesicle transport+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport","adaptor related protein complex 3 subunit sigma 2","[AP3S2_HUMAN|Reviewed]RecName: Full=AP-3 complex subunit sigma-2; AltName: Full=AP-3 complex subunit sigma-3B; AltName: Full=Adaptor-related protein complex 3 subunit sigma-2; AltName: Full=Sigma-3B-adaptin; Short=Sigma3B-adaptin; AltName: Full=Sigma-adaptin 3b;+++[A0A024RC62_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_a {ECO:0000313|EMBL:EAX02073.1};+++[A0A087WY05_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000481434};+++[H0YKM3_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000452862};+++[H0YLI7_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453223}; SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_d {ECO:0000313|EMBL:EAX02075.1};+++[H0YLX6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453380};+++[H0YN38_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[H0YNI6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000454027};+++[Q6PK37_HUMAN|Unreviewed]SubName: Full=AP3S2 protein {ECO:0000313|EMBL:AAH07773.1}; Flags: Fragment;"]
[1024,"'CDK8'",343,312,273,309.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016592///mediator complex+++GO:0032991///protein-containing complex","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0006468///protein phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016310///phosphorylation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051726///regulation of cell cycle","cyclin dependent kinase 8","[CDK8_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 8; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cell division protein kinase 8; AltName: Full=Mediator complex subunit CDK8; AltName: Full=Mediator of RNA polymerase II transcription subunit CDK8; AltName: Full=Protein kinase K35;+++[A0A0D9SEP3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000485883}; Flags: Fragment;+++[A0A0D9SFZ2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000487013}; Flags: Fragment;+++[F5H6D4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000437696};+++[Q64FY6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:AAU29339.1};+++[U4PPA3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:CDI06887.1}; Flags: Fragment;"]
[10240,"'MRPS31'",120,115,127,120.666666666667,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05202///Transcriptional misregulation in cancer+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04910///Insulin signaling pathway+++05200///Pathways in cancer+++05215///Prostate cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++04922///Glucagon signaling pathway+++04919///Thyroid hormone signaling pathway+++04068///FoxO signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++05165///Human papillomavirus infection+++04218///Cellular senescence","H00037///Alveolar rhabdomyosarcoma","M00676///PI3K-Akt signaling",null,"GO:0005763///mitochondrial small ribosomal subunit+++GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0005730///nucleolus","GO:0003735///structural constituent of ribosome+++GO:0019904///protein domain specific binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation","mitochondrial ribosomal protein S31","[RT31_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S31, mitochondrial; Short=MRP-S31; Short=S31mt; AltName: Full=Imogen 38; AltName: Full=Mitochondrial small ribosomal subunit protein mS31 {ECO:0000303|PubMed:25838379}; Flags: Precursor;"]
[10241,"'CALCOCO2'",2581,1965,2070,2205.33333333333,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0000421///autophagosome membrane+++GO:0005776///autophagosome+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0016032///viral process+++GO:0034341///response to interferon-gamma+++GO:1901098///positive regulation of autophagosome maturation+++GO:0006914///autophagy+++GO:0098792///xenophagy","calcium binding and coiled-coil domain 2","[CACO2_HUMAN|Reviewed]RecName: Full=Calcium-binding and coiled-coil domain-containing protein 2; AltName: Full=Antigen nuclear dot 52 kDa protein; AltName: Full=Nuclear domain 10 protein NDP52 {ECO:0000305}; Short=Nuclear domain 10 protein 52 {ECO:0000303|PubMed:7540613}; AltName: Full=Nuclear dot protein 52 {ECO:0000303|PubMed:9230084};+++[D6RBF9_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424169}; Flags: Fragment;+++[D6RBI4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422697}; Flags: Fragment;+++[D6REB0_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425090}; Flags: Fragment;+++[D6RF70_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424889}; Flags: Fragment;+++[D6RJE7_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425692}; Flags: Fragment;+++[H0Y9G3_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424083}; Flags: Fragment;+++[H0YBP4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429963}; Flags: Fragment;+++[I3L493_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461083}; Flags: Fragment;+++[I3L4E1_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461184};"]
[10243,"'GPHN'",165,101,120,128.666666666667,"00790///Folate biosynthesis+++01100///Metabolic pathways+++04727///GABAergic synapse","H00192///Xanthinuria+++H00769///Hyperekplexia",null,"R09735///adenylyl-molybdopterin:molybdate molybdate transferase (AMP-forming)   Adenylated molybdopterin + Molybdate <=> Molybdoenzyme molybdenum cofactor + AMP + H2O+++R09726///ATP:molybdopterin adenylyltransferase   ATP + Molybdopterin <=> Diphosphate + Adenylated molybdopterin","GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0099634///postsynaptic specialization membrane+++GO:0005856///cytoskeleton+++GO:0099572///postsynaptic specialization+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0005829///cytosol","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0061598///molybdopterin adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0008940///nitrate reductase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0061599///molybdopterin molybdotransferase activity+++GO:0043546///molybdopterin cofactor binding","GO:0018315///molybdenum incorporation into molybdenum-molybdopterin complex+++GO:0055114///oxidation-reduction process+++GO:0032324///molybdopterin cofactor biosynthetic process+++GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0007529///establishment of synaptic specificity at neuromuscular junction+++GO:0008152///metabolic process+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0010038///response to metal ion+++GO:0072579///glycine receptor clustering+++GO:0097112///gamma-aminobutyric acid receptor clustering","gephyrin","[GEPH_HUMAN|Reviewed]RecName: Full=Gephyrin {ECO:0000303|PubMed:10839351}; Includes: RecName: Full=Molybdopterin adenylyltransferase; Short=MPT adenylyltransferase; EC=2.7.7.75 {ECO:0000305|PubMed:26613940}; AltName: Full=Domain G; Includes: RecName: Full=Molybdopterin molybdenumtransferase; Short=MPT Mo-transferase; EC=2.10.1.1 {ECO:0000305|PubMed:22040219, ECO:0000305|PubMed:26613940}; AltName: Full=Domain E;+++[F5H039_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000438404};+++[G3V355_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451056};+++[G3V4D2_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451725};+++[G3V4R0_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451935};+++[G3V582_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452220};+++[H0YIY4_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450442}; Flags: Fragment;+++[H0YJ30_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450706}; Flags: Fragment;+++[H0YJR5_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452009}; Flags: Fragment;"]
[10244,"'RABEPK'",207,241,264,237.333333333333,"04141///Protein processing in endoplasmic reticulum+++03060///Protein export+++04918///Thyroid hormone synthesis+++05020///Prion diseases",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0005737///cytoplasm","GO:0051082///unfolded protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0051787///misfolded protein binding+++GO:0019904///protein domain specific binding+++GO:0043022///ribosome binding+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0016887///ATPase activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051087///chaperone binding","GO:0006904///vesicle docking involved in exocytosis+++GO:0006898///receptor-mediated endocytosis","Rab9 effector protein with kelch motifs","[RABEK_HUMAN|Reviewed]RecName: Full=Rab9 effector protein with kelch motifs; AltName: Full=40 kDa Rab9 effector protein; AltName: Full=p40;+++[A0A024R8A0_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 1 {ECO:0000313|EMBL:ALQ33965.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_c {ECO:0000313|EMBL:EAW87619.1};+++[A0A0S2Z4Z1_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 5 {ECO:0000313|EMBL:ALQ33969.1}; Flags: Fragment;+++[A0A0S2Z4Z5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 4 {ECO:0000313|EMBL:ALQ33968.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_d {ECO:0000313|EMBL:EAW87617.1}; Flags: Fragment;+++[A0A0S2Z506_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 3 {ECO:0000313|EMBL:ALQ33967.1};+++[A0A0S2Z553_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 2 {ECO:0000313|EMBL:ALQ33966.1};+++[Q5T1S4_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000362645};+++[Q5T1S5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000402234}; Flags: Fragment;"]
[10245,"'TIMM17B'",416,396,572,461.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane","GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport","translocase of inner mitochondrial membrane 17B","[TI17B_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B;+++[Q8NCS3_HUMAN|Unreviewed]SubName: Full=TIMM17B protein {ECO:0000313|EMBL:AAH29446.1}; Flags: Fragment;+++[V9GYK7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000476861};+++[V9GYS0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477027};+++[V9GYU0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477085}; Flags: Fragment;"]
[10247,"'RIDA'",83,108,96,95.6666666666667,{"$nulls":3},"R11099///2-iminopropanoate aminohydrolase   2-Iminopropanoate + H2O <=> Pyruvate + Ammonia+++R11098///2-iminobutanoate aminohydrolase   2-Iminobutanoate + H2O <=> 2-Oxobutanoate + Ammonia","GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0042803///protein homodimerization activity+++GO:0036041///long-chain fatty acid binding+++GO:1904013///xenon atom binding+++GO:0016787///hydrolase activity+++GO:0046914///transition metal ion binding+++GO:0003723///RNA binding+++GO:0016892///endoribonuclease activity, producing 3'-phosphomonoesters+++GO:0043167///ion binding+++GO:0019239///deaminase activity+++GO:1904012///platinum binding","GO:1901565///organonitrogen compound catabolic process+++GO:0001822///kidney development+++GO:0019518///L-threonine catabolic process to glycine+++GO:1902074///response to salt+++GO:0070314///G1 to G0 transition+++GO:0017148///negative regulation of translation+++GO:0030324///lung development+++GO:0007420///brain development+++GO:0033993///response to lipid+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","reactive intermediate imine deaminase A homolog","[RIDA_HUMAN|Reviewed]RecName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000305|PubMed:22094463}; EC=3.5.99.10 {ECO:0000269|PubMed:22094463}; AltName: Full=14.5 kDa translational inhibitor protein {ECO:0000303|PubMed:8973653}; Short=hp14.5 {ECO:0000303|PubMed:14997576}; Short=p14.5 {ECO:0000303|PubMed:8973653}; AltName: Full=Heat-responsive protein 12 {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Reactive intermediate imine deaminase A homolog {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Translation inhibitor L-PSP ribonuclease {ECO:0000250|UniProtKB:P52759}; EC=3.1.-.- {ECO:0000250|UniProtKB:P52759}; AltName: Full=UK114 antigen homolog {ECO:0000305|PubMed:20817725};+++[A0A024R9H2_HUMAN|Unreviewed]SubName: Full=Heat-responsive protein 12, isoform CRA_a {ECO:0000313|EMBL:EAW91775.1};+++[E5RIP8_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000429321};+++[H0YB34_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000428596}; Flags: Fragment;+++[H0YBX3_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000430482}; Flags: Fragment;"]
[10248,"'POP7'",370,355,456,393.666666666667,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005634///nucleus+++GO:0000172///ribonuclease MRP complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005654///nucleoplasm","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0001682///tRNA 5'-leader removal+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0008033///tRNA processing","POP7 homolog, ribonuclease P/MRP subunit","[POP7_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p20; Short=RNaseP protein p20; EC=3.1.26.5; AltName: Full=Ribonucleases P/MRP protein subunit POP7 homolog; Short=hPOP7;+++[C9JYM0_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p20 {ECO:0000313|Ensembl:ENSP00000387814}; Flags: Fragment;"]
[10249,"'GLYAT'",0,0,1,0.333333333333333,"00360///Phenylalanine metabolism",null,null,"R02452///benzoyl-CoA:glycine N-benzoyltransferase   Benzoyl-CoA + Glycine <=> CoA + Hippurate","GO:0005794///Golgi apparatus+++GO:0005759///mitochondrial matrix+++GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0016020///membrane+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005758///mitochondrial intermembrane space+++GO:0005777///peroxisome+++GO:0034774///secretory granule lumen+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005925///focal adhesion+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005764///lysosome+++GO:0070062///extracellular exosome","GO:0016209///antioxidant activity+++GO:0004096///catalase activity+++GO:0004601///peroxidase activity+++GO:0004046///aminoacylase activity+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding+++GO:0050661///NADP binding+++GO:0046872///metal ion binding+++GO:0005102///signaling receptor binding+++GO:0016684///oxidoreductase activity, acting on peroxide as acceptor+++GO:0047962///glycine N-benzoyltransferase activity+++GO:0020037///heme binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0016491///oxidoreductase activity+++GO:0047961///glycine N-acyltransferase activity+++GO:0005515///protein binding","GO:0001666///response to hypoxia+++GO:0055093///response to hyperoxia+++GO:1901787///benzoyl-CoA metabolic process+++GO:0014823///response to activity+++GO:0051781///positive regulation of cell division+++GO:0006544///glycine metabolic process+++GO:0033591///response to L-ascorbic acid+++GO:0001649///osteoblast differentiation+++GO:0043312///neutrophil degranulation+++GO:0000302///response to reactive oxygen species+++GO:0045471///response to ethanol+++GO:0034599///cellular response to oxidative stress+++GO:0042744///hydrogen peroxide catabolic process+++GO:0042542///response to hydrogen peroxide+++GO:0042493///response to drug+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0009650///UV protection+++GO:0032787///monocarboxylic acid metabolic process+++GO:0098869///cellular oxidant detoxification+++GO:0009060///aerobic respiration+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051262///protein tetramerization+++GO:0009636///response to toxic substance+++GO:0032868///response to insulin+++GO:0070542///response to fatty acid+++GO:0033189///response to vitamin A+++GO:0009642///response to light intensity+++GO:0043066///negative regulation of apoptotic process+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0033197///response to vitamin E+++GO:0020027///hemoglobin metabolic process+++GO:0010193///response to ozone+++GO:0032355///response to estradiol+++GO:0009411///response to UV+++GO:0001822///kidney development+++GO:0006625///protein targeting to peroxisome+++GO:0014854///response to inactivity+++GO:0080184///response to phenylpropanoid+++GO:0006637///acyl-CoA metabolic process+++GO:0010288///response to lead ion+++GO:0055114///oxidation-reduction process+++GO:0009314///response to radiation+++GO:0006979///response to oxidative stress+++GO:0071363///cellular response to growth factor stimulus+++GO:0006641///triglyceride metabolic process+++GO:0046686///response to cadmium ion+++GO:0001657///ureteric bud development+++GO:0006805///xenobiotic metabolic process+++GO:0007568///aging+++GO:0051289///protein homotetramerization+++GO:0008203///cholesterol metabolic process","glycine-N-acyltransferase","[GLYAT_HUMAN|Reviewed]RecName: Full=Glycine N-acyltransferase {ECO:0000303|PubMed:10630424}; EC=2.3.1.13 {ECO:0000303|PubMed:22475485, ECO:0000303|PubMed:7802672}; AltName: Full=Acyl-CoA:glycine N-acyltransferase; Short=AAc; AltName: Full=Aralkyl acyl-CoA N-acyltransferase; AltName: Full=Aralkyl acyl-CoA:amino acid N-acyltransferase; AltName: Full=Benzoyl-coenzyme A:glycine N-acyltransferase; AltName: Full=Glycine N-benzoyltransferase; EC=2.3.1.71 {ECO:0000303|PubMed:22475485, ECO:0000303|PubMed:7802672}; AltName: Full=HRP-1(CLP);+++[K7ES21_HUMAN|Unreviewed]SubName: Full=Glycine N-acyltransferase {ECO:0000313|Ensembl:ENSP00000468512}; Flags: Fragment;"]
[1025,"'CDK9'",665,765,703,711,"05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005694///chromosome+++GO:0016020///membrane+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0008023///transcription elongation factor complex+++GO:0000790///nuclear chromatin+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0001223///transcription coactivator binding+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0017069///snRNA binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0004672///protein kinase activity+++GO:0030332///cyclin binding+++GO:0097322///7SK snRNA binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0031297///replication fork processing+++GO:0031056///regulation of histone modification+++GO:0006468///protein phosphorylation+++GO:0007346///regulation of mitotic cell cycle+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0071157///negative regulation of cell cycle arrest+++GO:1903839///positive regulation of mRNA 3'-UTR binding+++GO:0016310///phosphorylation+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0006282///regulation of DNA repair+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0042493///response to drug+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0051147///regulation of muscle cell differentiation+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0033129///positive regulation of histone phosphorylation+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0050434///positive regulation of viral transcription","cyclin dependent kinase 9","[CDK9_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 9; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=C-2K; AltName: Full=Cell division cycle 2-like protein kinase 4; AltName: Full=Cell division protein kinase 9; AltName: Full=Serine/threonine-protein kinase PITALRE; AltName: Full=Tat-associated kinase complex catalytic subunit;+++[A0A024R880_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 (CDC2-related kinase), isoform CRA_a {ECO:0000313|EMBL:EAW87697.1};+++[B5BU53_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|EMBL:BAG70103.1};+++[X6RE90_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|Ensembl:ENSP00000395872}; Flags: Fragment;"]
[10250,"'SRRM1'",2704,2728,2436,2622.66666666667,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006405///RNA export from nucleus+++GO:0031124///mRNA 3'-end processing+++GO:0006406///mRNA export from nucleus","serine and arginine repetitive matrix 1","[SRRM1_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 1; AltName: Full=SR-related nuclear matrix protein of 160 kDa; Short=SRm160; AltName: Full=Ser/Arg-related nuclear matrix protein;+++[A0A0S2Z4W1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 1 {ECO:0000313|EMBL:ALQ33970.1}; SubName: Full=Serine/arginine repetitive matrix 1, isoform CRA_a {ECO:0000313|EMBL:EAW95138.1}; Flags: Fragment;+++[A0A0S2Z4Z6_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 2 {ECO:0000313|EMBL:ALQ33971.1}; Flags: Fragment;+++[A9Z1X7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000363510};+++[B7Z7U0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61739, highly similar to Serine/arginine repetitive matrix protein 1 {ECO:0000313|EMBL:BAH13726.1};+++[E9PCT1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000391430};+++[M0QXG5_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000469151}; Flags: Fragment;+++[M0R088_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471084}; Flags: Fragment;+++[M0R1E7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471819};"]
[10251,"'SPRY3'",47,55,39,47,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function","GO:0061564///axon development+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046580///negative regulation of Ras protein signal transduction","sprouty RTK signaling antagonist 3","[SPY3_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 3; Short=Spry-3;+++[Q6ZUP3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43494 fis, clone PEBLM2000170, moderately similar to Sprouty homolog 3 {ECO:0000313|EMBL:BAC86177.1};"]
[10252,"'SPRY1'",156,76,111,114.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0009966///regulation of signal transduction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0001656///metanephros development+++GO:0007275///multicellular organism development+++GO:0001759///organ induction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0001657///ureteric bud development+++GO:0008285///negative regulation of cell proliferation+++GO:0060940///epithelial to mesenchymal transition involved in cardiac fibroblast development+++GO:0060449///bud elongation involved in lung branching","sprouty RTK signaling antagonist 1","[SPY1_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 1; Short=Spry-1;+++[D6REX7_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421622}; Flags: Fragment;+++[D6RHD2_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421036}; Flags: Fragment;+++[D6RIE6_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000425946}; Flags: Fragment;+++[L8E896_HUMAN|Unreviewed]SubName: Full=Alternative protein SPRY1 {ECO:0000313|EMBL:CCQ43339.1};"]
[10253,"'SPRY2'",726,628,696,683.333333333333,"04013///MAPK signaling pathway - fly+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015630///microtubule cytoskeleton+++GO:0042995///cell projection+++GO:0032587///ruffle membrane+++GO:0005634///nucleus","GO:0043539///protein serine/threonine kinase activator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity","GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0034260///negative regulation of GTPase activity+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0060541///respiratory system development+++GO:0030324///lung development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0016525///negative regulation of angiogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0031345///negative regulation of cell projection organization+++GO:0030335///positive regulation of cell migration+++GO:0060437///lung growth+++GO:0043407///negative regulation of MAP kinase activity+++GO:0007275///multicellular organism development+++GO:0045595///regulation of cell differentiation+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0060425///lung morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0045165///cell fate commitment+++GO:0060449///bud elongation involved in lung branching+++GO:0010628///positive regulation of gene expression+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0042127///regulation of cell proliferation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway","sprouty RTK signaling antagonist 2","[SPY2_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 2; Short=Spry-2;"]
[10254,"'STAM2'",435,458,374,422.333333333333,"04630///Jak-STAT signaling pathway+++04144///Endocytosis",null,"M00408///ESCRT-0 complex",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0033565///ESCRT-0 complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome","GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0036258///multivesicular body assembly+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0061024///membrane organization+++GO:0016236///macroautophagy+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport","signal transducing adaptor molecule 2","[STAM2_HUMAN|Reviewed]RecName: Full=Signal transducing adapter molecule 2; Short=STAM-2; AltName: Full=Hrs-binding protein;"]
[10256,"'CNKSR1'",14,17,22,17.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0007266///Rho protein signal transduction","connector enhancer of kinase suppressor of Ras 1","[CNKR1_HUMAN|Reviewed]RecName: Full=Connector enhancer of kinase suppressor of ras 1; Short=Connector enhancer of KSR 1; AltName: Full=CNK homolog protein 1; Short=CNK1; Short=hCNK1; AltName: Full=Connector enhancer of KSR-like;+++[B4DL25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60656, highly similar to Connector enhancer of kinase suppressor ofras 1 {ECO:0000313|EMBL:BAG59387.1};+++[B4DXN4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59272, highly similar to Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|EMBL:BAG63446.1};+++[E9PIE0_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000432057};+++[E9PS82_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000435880};+++[G3V160_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_a {ECO:0000313|EMBL:EAX07840.1}; SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000431817};+++[H0YDP5_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000434047}; Flags: Fragment;+++[Q53GM7_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1 variant {ECO:0000313|EMBL:BAD96624.1}; SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_b {ECO:0000313|EMBL:EAX07841.1}; Flags: Fragment;"]
[10257,"'ABCC4'",139,167,124,143.333333333333,"02010///ABC transporters+++04976///Bile secretion+++04024///cAMP signaling pathway+++01523///Antifolate resistance",{"$nulls":3},"GO:0031088///platelet dense granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0016404///15-hydroxyprostaglandin dehydrogenase (NAD+) activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances","GO:0055085///transmembrane transport+++GO:0010243///response to organonitrogen compound+++GO:0060271///cilium assembly+++GO:0008150///biological_process+++GO:0002576///platelet degranulation+++GO:0010033///response to organic substance+++GO:0099131///ATP hydrolysis coupled ion transmembrane transport+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0042493///response to drug+++GO:0014070///response to organic cyclic compound+++GO:0032310///prostaglandin secretion+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0055114///oxidation-reduction process","ATP binding cassette subfamily C member 4","[MRP4_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 4; AltName: Full=ATP-binding cassette sub-family C member 4; AltName: Full=MRP/cMOAT-related ABC transporter; AltName: Full=Multi-specific organic anion transporter B; Short=MOAT-B;+++[A0A2R8Y5Z3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494938}; Flags: Fragment;+++[A0A2R8Y6V8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000495513};+++[A0A2R8YDC1_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494431}; Flags: Fragment;+++[A0A2R8YDG7_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493766};+++[A8K2Q2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77042, highly similar to Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4, mRNA {ECO:0000313|EMBL:BAF83006.1};+++[O75555_HUMAN|Unreviewed]SubName: Full=ABC transporter MOAT-B isoform {ECO:0000313|EMBL:AAC27077.1}; Flags: Fragment;+++[Q8IUA3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 1 {ECO:0000313|EMBL:AAN08629.1}; SubName: Full=ATP-binding cassette subfamily C member 4 variant 3 {ECO:0000313|EMBL:AAN08630.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_a {ECO:0000313|EMBL:EAX08949.1};+++[Q8IWU1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 2 {ECO:0000313|EMBL:AAN08628.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_d {ECO:0000313|EMBL:EAX08952.1}; SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493861};"]
[1026,"'CDKN1A'",11161,15125,13806,13364,"04928///Parathyroid hormone synthesis, secretion and action+++01522///Endocrine resistance+++05219///Bladder cancer+++04921///Oxytocin signaling pathway+++05203///Viral carcinogenesis+++05226///Gastric cancer+++05165///Human papillomavirus infection+++04066///HIF-1 signaling pathway+++05217///Basal cell carcinoma+++04068///FoxO signaling pathway+++04012///ErbB signaling pathway+++05215///Prostate cancer+++05225///Hepatocellular carcinoma+++04934///Cushing's syndrome+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++01524///Platinum drug resistance+++05218///Melanoma+++05166///HTLV-I infection+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++05160///Hepatitis C+++04115///p53 signaling pathway+++05220///Chronic myeloid leukemia+++04110///Cell cycle+++05212///Pancreatic cancer+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05161///Hepatitis B+++05223///Non-small cell lung cancer+++05214///Glioma+++04630///Jak-STAT signaling pathway+++05222///Small cell lung cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05211///Renal cell carcinoma+++04218///Cellular senescence+++05224///Breast cancer+++05163///Human cytomegalovirus infection+++05213///Endometrial cancer+++05216///Thyroid cancer","H00030///Cervical cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0070557///PCNA-p21 complex+++GO:0032991///protein-containing complex+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex","GO:0044877///protein-containing complex binding+++GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019912///cyclin-dependent protein kinase activating kinase activity+++GO:0016301///kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0030332///cyclin binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:0009636///response to toxic substance+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:0090398///cellular senescence+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010243///response to organonitrogen compound+++GO:0072331///signal transduction by p53 class mediator+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0071850///mitotic cell cycle arrest+++GO:0006974///cellular response to DNA damage stimulus+++GO:0055093///response to hyperoxia+++GO:0034198///cellular response to amino acid starvation+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0042326///negative regulation of phosphorylation+++GO:0010165///response to X-ray+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0051412///response to corticosterone+++GO:0014070///response to organic cyclic compound+++GO:0010033///response to organic substance+++GO:0043066///negative regulation of apoptotic process+++GO:0042493///response to drug+++GO:0046685///response to arsenic-containing substance+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0090399///replicative senescence+++GO:0007265///Ras protein signal transduction+++GO:0090400///stress-induced premature senescence+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034605///cellular response to heat+++GO:0045860///positive regulation of protein kinase activity+++GO:0071493///cellular response to UV-B+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0060574///intestinal epithelial cell maturation+++GO:0007050///cell cycle arrest+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0031668///cellular response to extracellular stimulus+++GO:0007346///regulation of mitotic cell cycle+++GO:0051384///response to glucocorticoid+++GO:0031100///animal organ regeneration+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050821///protein stabilization+++GO:0007507///heart development+++GO:0030308///negative regulation of cell growth+++GO:0071479///cellular response to ionizing radiation+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle","cyclin dependent kinase inhibitor 1A","[CDN1A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1; AltName: Full=CDK-interacting protein 1; AltName: Full=Melanoma differentiation-associated protein 6; Short=MDA-6; AltName: Full=p21;+++[A0A024RCX5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_a {ECO:0000313|EMBL:EAX03907.1};"]
[10260,"'DENND4A'",528,433,294,418.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0006355///regulation of transcription, DNA-templated","DENN domain containing 4A","[MYCPP_HUMAN|Reviewed]RecName: Full=C-myc promoter-binding protein; AltName: Full=DENN domain-containing protein 4A;+++[A0A0U1RR27_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000489304};+++[H3BSA0_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000456605}; Flags: Fragment;+++[H3BTW5_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000457358}; Flags: Fragment;+++[Q05C90_HUMAN|Unreviewed]SubName: Full=DENND4A protein {ECO:0000313|EMBL:AAH28057.1}; Flags: Fragment;"]
[10262,"'SF3B4'",1490,1531,1915,1645.33333333333,"03040///Spliceosome","H01376///Acrofacial dysostosis","M00352///Spliceosome, U2-snRNP",null,"GO:0005912///adherens junction+++GO:0005913///cell-cell adherens junction+++GO:0045177///apical part of cell+++GO:0016607///nuclear speck+++GO:0005730///nucleolus+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0070160///tight junction+++GO:0030054///cell junction+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0051015///actin filament binding+++GO:0050839///cell adhesion molecule binding+++GO:0003676///nucleic acid binding+++GO:0045296///cadherin binding+++GO:0017016///Ras GTPase binding+++GO:0003723///RNA binding","GO:0061951///establishment of protein localization to plasma membrane+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0034332///adherens junction organization+++GO:0060019///radial glial cell differentiation+++GO:0007267///cell-cell signaling+++GO:0060563///neuroepithelial cell differentiation+++GO:0043547///positive regulation of GTPase activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0007165///signal transduction+++GO:0007155///cell adhesion+++GO:0048872///homeostasis of number of cells+++GO:0034334///adherens junction maintenance+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0032880///regulation of protein localization+++GO:0030336///negative regulation of cell migration+++GO:0048854///brain morphogenesis+++GO:0021987///cerebral cortex development+++GO:1902414///protein localization to cell junction+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0008380///RNA splicing+++GO:0070830///bicellular tight junction assembly+++GO:0021537///telencephalon development","splicing factor 3b subunit 4","[SF3B4_HUMAN|Reviewed]RecName: Full=Splicing factor 3B subunit 4; AltName: Full=Pre-mRNA-splicing factor SF3b 49 kDa subunit; AltName: Full=Spliceosome-associated protein 49; Short=SAP 49;+++[B3KUJ0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39996 fis, clone STOMA2002166, highly similar to Splicing factor 3B subunit 4 {ECO:0000313|EMBL:BAG53452.1};+++[Q5SZ64_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 4 {ECO:0000313|Ensembl:ENSP00000391114}; SubName: Full=Splicing factor 3b, subunit 4, 49kDa {ECO:0000313|EMBL:CAI12647.1}; Flags: Fragment;"]
[10263,"'CDK2AP2'",1114,994,1119,1075.66666666667,{"$nulls":4},"GO:0005874///microtubule+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:2000035///regulation of stem cell division","cyclin dependent kinase 2 associated protein 2","[CDKA2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein 2; Short=CDK2-associated protein 2; AltName: Full=DOC-1-related protein; Short=DOC-1R;+++[E9PKR4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000431503};+++[E9PQJ3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000436213};+++[Q6IAV4_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein {ECO:0000256|PIRNR:PIRNR037709};"]
[10265,"'IRX5'",0,4,1,1.66666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005499///vitamin D binding+++GO:0003677///DNA binding","GO:0048468///cell development+++GO:0060040///retinal bipolar neuron differentiation+++GO:0010468///regulation of gene expression+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0042551///neuron maturation+++GO:0050896///response to stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007601///visual perception+++GO:0008406///gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0002027///regulation of heart rate","iroquois homeobox 5","[IRX5_HUMAN|Reviewed]RecName: Full=Iroquois-class homeodomain protein IRX-5; AltName: Full=Homeodomain protein IRX-2A; AltName: Full=Homeodomain protein IRXB2; AltName: Full=Iroquois homeobox protein 5;+++[A2RRB5_HUMAN|Unreviewed]SubName: Full=IRX5 protein {ECO:0000313|EMBL:AAI31511.1}; SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000483446};+++[H0YML8_HUMAN|Unreviewed]SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000453660};"]
[10266,"'RAMP2'",16,22,23,20.3333333333333,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0150057///amylin receptor complex 2+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005887///integral component of plasma membrane+++GO:0005623///cell+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:1903143///adrenomedullin receptor complex+++GO:0043235///receptor complex","GO:0005515///protein binding+++GO:0001605///adrenomedullin receptor activity+++GO:0008565///protein transporter activity+++GO:0097643///amylin receptor activity+++GO:0015026///coreceptor activity+++GO:1990409///adrenomedullin binding","GO:0043116///negative regulation of vascular permeability+++GO:2001214///positive regulation of vasculogenesis+++GO:0002040///sprouting angiogenesis+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032570///response to progesterone+++GO:0031623///receptor internalization+++GO:0001666///response to hypoxia+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0001570///vasculogenesis+++GO:0006816///calcium ion transport+++GO:0070830///bicellular tight junction assembly+++GO:0008217///regulation of blood pressure+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006886///intracellular protein transport+++GO:0032355///response to estradiol+++GO:0015031///protein transport+++GO:0097084///vascular smooth muscle cell development+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0070831///basement membrane assembly+++GO:0097647///amylin receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0001525///angiogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0034333///adherens junction assembly+++GO:0045766///positive regulation of angiogenesis+++GO:0007565///female pregnancy+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010628///positive regulation of gene expression","receptor activity modifying protein 2","[RAMP2_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 2; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 2; Short=CRLR activity-modifying protein 2; Flags: Precursor;+++[A0A024R1Z2_HUMAN|Unreviewed]SubName: Full=Receptor (Calcitonin) activity modifying protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW60878.1};+++[K7EKQ3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000465725};+++[K7ENJ8_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000466980}; Flags: Fragment;+++[K7EPN3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000467463};"]
[10267,"'RAMP1'",549,516,609,558,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:1990406///CGRP receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0150056///amylin receptor complex 1+++GO:0009986///cell surface+++GO:0005623///cell+++GO:0043235///receptor complex+++GO:0005886///plasma membrane","GO:0097643///amylin receptor activity+++GO:1990407///calcitonin gene-related peptide binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0008565///protein transporter activity+++GO:0015026///coreceptor activity+++GO:0005515///protein binding","GO:0060050///positive regulation of protein glycosylation+++GO:0006886///intracellular protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0001525///angiogenesis+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0015031///protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0097647///amylin receptor signaling pathway+++GO:0031623///receptor internalization+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0006816///calcium ion transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway","receptor activity modifying protein 1","[RAMP1_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 1; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 1; Short=CRLR activity-modifying protein 1; Flags: Precursor;+++[E9PC20_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 1 {ECO:0000313|Ensembl:ENSP00000386720};+++[Q53SN3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY24219.1}; Flags: Fragment;+++[Q53T50_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY14674.1}; Flags: Fragment;"]
[10269,"'ZMPSTE24'",767,749,722,746,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis","H00665///Mandibuloacral dysplasia+++H00663///Restrictive dermopathy",null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005635///nuclear envelope+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0004175///endopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0008235///metalloexopeptidase activity+++GO:0016787///hydrolase activity+++GO:0003690///double-stranded DNA binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0046872///metal ion binding","GO:0061337///cardiac conduction+++GO:0051276///chromosome organization+++GO:0060993///kidney morphogenesis+++GO:0003231///cardiac ventricle development+++GO:0003007///heart morphogenesis+++GO:0032006///regulation of TOR signaling+++GO:0032350///regulation of hormone metabolic process+++GO:0006998///nuclear envelope organization+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0040014///regulation of multicellular organism growth+++GO:0003417///growth plate cartilage development+++GO:0010629///negative regulation of gene expression+++GO:1990164///histone H2A phosphorylation+++GO:0090239///regulation of histone H4 acetylation+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:1903522///regulation of blood circulation+++GO:0007628///adult walking behavior+++GO:1903463///regulation of mitotic cell cycle DNA replication+++GO:0050905///neuromuscular process+++GO:0008016///regulation of heart contraction+++GO:0044030///regulation of DNA methylation+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:0006508///proteolysis+++GO:0070302///regulation of stress-activated protein kinase signaling cascade+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0030327///prenylated protein catabolic process+++GO:0071586///CAAX-box protein processing+++GO:0010506///regulation of autophagy+++GO:0001889///liver development+++GO:0010628///positive regulation of gene expression+++GO:0072423///response to DNA damage checkpoint signaling+++GO:0030500///regulation of bone mineralization+++GO:0044029///hypomethylation of CpG island+++GO:0048538///thymus development+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0043969///histone H2B acetylation+++GO:0035264///multicellular organism growth+++GO:0006281///DNA repair+++GO:0048145///regulation of fibroblast proliferation+++GO:0019216///regulation of lipid metabolic process+++GO:0006997///nucleus organization+++GO:0006325///chromatin organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0050688///regulation of defense response to virus+++GO:0008544///epidermis development+++GO:0030282///bone mineralization+++GO:0043007///maintenance of rDNA+++GO:1990036///calcium ion import into sarcoplasmic reticulum+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001942///hair follicle development+++GO:0006925///inflammatory cell apoptotic process+++GO:0008340///determination of adult lifespan+++GO:0016485///protein processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0010906///regulation of glucose metabolic process+++GO:0048739///cardiac muscle fiber development+++GO:2000772///regulation of cellular senescence+++GO:0044255///cellular lipid metabolic process+++GO:0008360///regulation of cell shape+++GO:2000618///regulation of histone H4-K16 acetylation+++GO:0071480///cellular response to gamma radiation+++GO:0043979///histone H2B-K5 acetylation+++GO:2000730///regulation of termination of RNA polymerase I transcription","zinc metallopeptidase STE24","[FACE1_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 1 homolog; EC=3.4.24.84; AltName: Full=Farnesylated proteins-converting enzyme 1; Short=FACE-1; AltName: Full=Prenyl protein-specific endoprotease 1; AltName: Full=Zinc metalloproteinase Ste24 homolog;"]
[1027,"'CDKN1B'",549,384,412,448.333333333333,"05226///Gastric cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing's syndrome+++05206///MicroRNAs in cancer+++04066///HIF-1 signaling pathway+++05222///Small cell lung cancer+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++04012///ErbB signaling pathway+++05220///Chronic myeloid leukemia+++05169///Epstein-Barr virus infection+++05215///Prostate cancer+++05161///Hepatitis B+++04110///Cell cycle+++05162///Measles+++05203///Viral carcinogenesis","H00024///Prostate cancer+++H00018///Gastric cancer+++H01431///Cushing's syndrome+++H01102///Pituitary adenomas+++H00247///Multiple endocrine neoplasia syndrome (MEN)",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032991///protein-containing complex+++GO:0005768///endosome","GO:0051087///chaperone binding+++GO:0019903///protein phosphatase binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005072///transforming growth factor beta receptor, cytoplasmic mediator activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0044877///protein-containing complex binding","GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0051271///negative regulation of cellular component movement+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0043434///response to peptide hormone+++GO:0046686///response to cadmium ion+++GO:0009749///response to glucose+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0048839///inner ear development+++GO:0033673///negative regulation of kinase activity+++GO:0071285///cellular response to lithium ion+++GO:0045930///negative regulation of mitotic cell cycle+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042326///negative regulation of phosphorylation+++GO:0071236///cellular response to antibiotic+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007049///cell cycle+++GO:0014070///response to organic cyclic compound+++GO:0008219///cell death+++GO:0010942///positive regulation of cell death+++GO:0001666///response to hypoxia+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0008284///positive regulation of cell proliferation+++GO:0001890///placenta development+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0006813///potassium ion transport+++GO:0042493///response to drug+++GO:0045786///negative regulation of cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0031116///positive regulation of microtubule polymerization+++GO:0043200///response to amino acid+++GO:0071407///cellular response to organic cyclic compound+++GO:0007096///regulation of exit from mitosis+++GO:0042127///regulation of cell proliferation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest+++GO:0007507///heart development+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0007219///Notch signaling pathway+++GO:0007605///sensory perception of sound+++GO:0071850///mitotic cell cycle arrest+++GO:0045732///positive regulation of protein catabolic process+++GO:0032355///response to estradiol","cyclin dependent kinase inhibitor 1B","[CDN1B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1B; AltName: Full=Cyclin-dependent kinase inhibitor p27 {ECO:0000303|PubMed:28666995}; AltName: Full=p27Kip1 {ECO:0000303|PubMed:8033212};+++[A7KMP4_HUMAN|Unreviewed]SubName: Full=Truncated cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:ABS17636.1};+++[E7ES52_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000379629};+++[H7C2T1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000407597}; Flags: Fragment;+++[Q6I9V6_HUMAN|Unreviewed]SubName: Full=CDKN1B protein {ECO:0000313|EMBL:CAG33680.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:BAG70105.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B (P27, Kip1), isoform CRA_a {ECO:0000313|EMBL:EAW96275.1}; SubName: Full=cDNA, FLJ92816, Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1)(CDKN1B), mRNA {ECO:0000313|EMBL:BAG35368.1};+++[Q708J1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:CAE82383.1}; Flags: Fragment;"]
[10270,"'AKAP8'",347,386,330,354.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001939///female pronucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000793///condensed chromosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0046872///metal ion binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051059///NF-kappaB binding+++GO:0003723///RNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0042826///histone deacetylase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0002376///immune system process+++GO:0000278///mitotic cell cycle+++GO:0031065///positive regulation of histone deacetylation+++GO:0044839///cell cycle G2/M phase transition+++GO:0033127///regulation of histone phosphorylation+++GO:0007165///signal transduction+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0007076///mitotic chromosome condensation+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0015031///protein transport+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response","A-kinase anchoring protein 8","[AKAP8_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 8; Short=AKAP-8; AltName: Full=A-kinase anchor protein 95 kDa; Short=AKAP 95;+++[M0QX51_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000468902};+++[M0QYL4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000469908}; Flags: Fragment;+++[Q8NE02_HUMAN|Unreviewed]SubName: Full=AKAP8 protein {ECO:0000313|EMBL:AAH37270.1};"]
[10272,"'FSTL3'",9830,14073,13785,12562.6666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0030141///secretory granule+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0044306///neuron projection terminus+++GO:0005576///extracellular region","GO:0001968///fibronectin binding+++GO:0048185///activin binding+++GO:0005515///protein binding","GO:0030325///adrenal gland development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0044267///cellular protein metabolic process+++GO:0030324///lung development+++GO:0007283///spermatogenesis+++GO:0001822///kidney development+++GO:0043687///post-translational protein modification+++GO:0001503///ossification+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0008584///male gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0071248///cellular response to metal ion+++GO:0090101///negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045671///negative regulation of osteoclast differentiation","follistatin like 3","[FSTL3_HUMAN|Reviewed]RecName: Full=Follistatin-related protein 3; AltName: Full=Follistatin-like protein 3; AltName: Full=Follistatin-related gene protein; Flags: Precursor;+++[A0A024R1Y8_HUMAN|Unreviewed]SubName: Full=Follistatin-like 3 (Secreted glycoprotein), isoform CRA_a {ECO:0000313|EMBL:EAW61166.1};+++[A0A087WTD3_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000477770}; Flags: Fragment;+++[A0A087X1Q2_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000484376}; Flags: Fragment;+++[K7EM71_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000466383};"]
[102723360,"'LOC102723360'",17.02,46.16,23.6,28.9266666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding","GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression","uncharacterized LOC102723360","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102723475,"'KCNE1B'",21.04,23.04,22.57,22.2166666666667,{"$nulls":4},"GO:0008076///voltage-gated potassium channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005251///delayed rectifier potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding","GO:0006811///ion transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0097623///potassium ion export across plasma membrane+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086011///membrane repolarization during action potential+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport","potassium voltage-gated channel subfamily E regulatory subunit 1B","[KCE1B_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000305};+++[A0A087WU88_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000478461};+++[A0A087WWU3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000480511}; Flags: Fragment;"]
[102723502,"'LOC102723502'",6,4,6,5.33333333333333,{"$nulls":7},"POTE ankyrin domain family member B-like","[A0A0G2JMU2_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000479963};+++[A0A0G2JQB7_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000485729};"]
[102723534,"'LOC102723534'",9,12,11.87,10.9566666666667,"04120///Ubiquitin mediated proteolysis","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0032183///SUMO binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0007283///spermatogenesis+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006886///intracellular protein transport","E3 ubiquitin-protein ligase HERC2-like","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[102723553,"'SMIM11B'",175.04,147.09,186.98,169.703333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"small integral membrane protein 11B","[SI11A_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11A {ECO:0000312|HGNC:HGNC:1293};+++[SI11B_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11B {ECO:0000312|HGNC:HGNC:51846};"]
[102723555,"'SPDYE16'",1,0,3,1.33333333333333,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E16","[SPD16_HUMAN|Reviewed]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[A0A0J9YVZ0_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487736};+++[A0A0J9YW45_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487806};+++[A0A0J9YWM7_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488034};+++[A0A0J9YYB4_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488772};+++[A0A0J9YYF2_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488825};"]
[102723623,"'LOC102723623'",0,0.96,0,0.32,{"$nulls":7},"golgin subfamily A member 6-like protein 6","[GG6L1_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 1;+++[GG6L2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 2;+++[GG6L6_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 6;+++[GG6L7_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 7 {ECO:0000305};+++[GG6LV_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};"]
[102723722,"'LOC102723722'",1.39,2.51,2.35,2.08333333333333,"01522///Endocrine resistance+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse","H01171///Poor drug metabolism (PM)",null,"R09421///4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP++++R08343///Citalopram <=> Demethylcitalopram+++R08345///Demethylcitalopram <=> Didemethylcitalopram+++R08344///Citalopram <=> Citalopram N-oxide+++R03697///Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen+++R08270///N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O+++R08267///Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O","GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005783///endoplasmic reticulum","GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0005506///iron ion binding+++GO:0004497///monooxygenase activity+++GO:0046872///metal ion binding+++GO:0008144///drug binding+++GO:0043023///ribosomal large subunit binding+++GO:0016491///oxidoreductase activity+++GO:0016887///ATPase activity+++GO:0008395///steroid hydroxylase activity+++GO:0005524///ATP binding+++GO:0043022///ribosome binding+++GO:0070330///aromatase activity+++GO:0005525///GTP binding+++GO:0020037///heme binding","GO:0090350///negative regulation of cellular organofluorine metabolic process+++GO:0017144///drug metabolic process+++GO:0016098///monoterpenoid metabolic process+++GO:0042737///drug catabolic process+++GO:0046034///ATP metabolic process+++GO:0051100///negative regulation of binding+++GO:0009820///alkaloid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0009804///coumarin metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0046483///heterocycle metabolic process+++GO:0033076///isoquinoline alkaloid metabolic process+++GO:0070989///oxidative demethylation+++GO:0009822///alkaloid catabolic process+++GO:0008202///steroid metabolic process+++GO:0042759///long-chain fatty acid biosynthetic process","uncharacterized LOC102723722","[CP2D6_HUMAN|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000269|PubMed:21576599}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000305|PubMed:21576599}; AltName: Full=Cytochrome P450-DB1; AltName: Full=Debrisoquine 4-hydroxylase;+++[CP2D6_PANPA|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D6_PANTR|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D7_HUMAN|diamond]RecName: Full=Putative cytochrome P450 2D7 {ECO:0000305}; EC=1.14.14.1 {ECO:0000269|PubMed:15051713};+++[CP2DH_MACFA|diamond]RecName: Full=Cytochrome P450 2D17; EC=1.14.14.1; AltName: Full=CYPIID17;+++[OLA1_BOVIN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_HUMAN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=DNA damage-regulated overexpressed in cancer 45; Short=DOC45; AltName: Full=GTP-binding protein 9;+++[OLA1_MOUSE|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=GTP-binding protein 9;+++[OLA1_PONAB|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_RAT|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};"]
[102723728,"'LOC102723728'",1109.09,1307.69,2161.26,1526.01333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding",null,"nodal modulator 3-like","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;"]
[102723750,"'LOC102723750'",2,1,2,1.66666666666667,{"$nulls":7},"uncharacterized LOC102723750","[K7DZX1_MONDO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000039072};+++[K7FQE9_PELSI|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000010259};"]
[102723849,"'SPDYE17'",1,0,0,0.333333333333333,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","speedy/RINGO cell cycle regulator family member E17","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE2_HUMAN|diamond]RecName: Full=Speedy protein E2;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPE2B_HUMAN|diamond]RecName: Full=Speedy protein E2B;"]
[102723859,"'TBC1D3E'",81.27,110.13,74.63,88.6766666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","TBC1 domain family member 3E","[TBC3E_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3E {ECO:0000312|HGNC:HGNC:27071};"]
[102723996,"'LOC102723996'",34.3,33.29,100.03,55.8733333333333,"04672///Intestinal immune network for IgA production+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0009986///cell surface+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding+++GO:0005102///signaling receptor binding","GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0042102///positive regulation of T cell proliferation+++GO:0031295///T cell costimulation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0042130///negative regulation of T cell proliferation+++GO:0006955///immune response","ICOS ligand","[ICOSL_HUMAN|Reviewed]RecName: Full=ICOS ligand; AltName: Full=B7 homolog 2; Short=B7-H2; AltName: Full=B7-like protein Gl50; AltName: Full=B7-related protein 1; Short=B7RP-1; AltName: CD_antigen=CD275; Flags: Precursor;+++[A0A087X1L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000484302};+++[A0A096LPE5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485557};+++[A0N0L8_HUMAN|Unreviewed]SubName: Full=Inducible T-cell co-stimulator ligand {ECO:0000313|EMBL:ABK41909.1}; SubName: Full=Inducible T-cell co-stimulator ligand, isoform CRA_c {ECO:0000313|EMBL:EAX09448.1}; SubName: Full=cDNA FLJ77643, highly similar to Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAF82881.1}; SubName: Full=cDNA, FLJ95137, Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAG36999.1};"]
[102724023,"'GATD3B'",178.77,271.39,327.2,259.12,{"$nulls":4},"GO:0005739///mitochondrion",null,null,"glutamine amidotransferase like class 1 domain containing 3B","[GAL3B_HUMAN|Reviewed]RecName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial; AltName: Full=Keio novel protein-I {ECO:0000303|PubMed:8753807}; Short=KNP-I {ECO:0000303|PubMed:8753807}; AltName: Full=Protein GT335 {ECO:0000303|PubMed:8975701}; AltName: Full=Protein HES1 {ECO:0000303|PubMed:9150728}; Flags: Precursor;+++[A0A096LNH5_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000483086};+++[A0A096LNJ1_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485058}; Flags: Fragment;+++[A0A096LP12_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000374340}; SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485335}; Flags: Fragment;+++[A0A096LP57_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485404};+++[A0A096LP73_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485439}; Flags: Fragment;+++[A0A0B4J2H4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485300};"]
[102724135,"'LOC102724135'",26.36,17.37,32.99,25.5733333333333,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0004691///cAMP-dependent protein kinase activity","GO:0035023///regulation of Rho protein signal transduction","uncharacterized LOC102724135","[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOG8S_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8S {ECO:0000305};"]
[102724159,"'LOC102724159'",115.52,128.71,126.42,123.55,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0032040///small-subunit processome","GO:0030515///snoRNA binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","periodic tryptophan protein 2 homolog","[PWP2_HUMAN|Reviewed]RecName: Full=Periodic tryptophan protein 2 homolog;+++[A0A0B4J2E5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000482107};+++[A0A0J9YX21_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000488213}; Flags: Fragment;"]
[102724197,"'LOC102724197'",2.08,2.47,1,1.85,"01100///Metabolic pathways+++00460///Cyanoamino acid metabolism+++00430///Taurine and hypotaurine metabolism+++00590///Arachidonic acid metabolism+++00480///Glutathione metabolism",null,null,"R09875///leukotriene-C4 hydrolase Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate+++R01687///(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase (5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine+++R00494///glutathione gamma-glutamylaminopeptidase Glutathione + H2O <=> Cys-Gly + L-Glutamate+++R03970///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase 3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O+++R03971///gamma-glutamyl-beta-aminopropiononitrile amidohydrolase 3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O+++R01262///glutathione:L-amino-acid 5-glutamyltransferase Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid+++R03916///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate","GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0036374///glutathione hydrolase activity+++GO:0000048///peptidyltransferase activity","GO:0006749///glutathione metabolic process+++GO:0019344///cysteine biosynthetic process+++GO:0031638///zymogen activation+++GO:0006751///glutathione catabolic process+++GO:0002682///regulation of immune system process+++GO:0006520///cellular amino acid metabolic process+++GO:0006412///translation+++GO:0031179///peptide modification+++GO:1901750///leukotriene D4 biosynthetic process+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0050727///regulation of inflammatory response+++GO:0032355///response to estradiol+++GO:0034612///response to tumor necrosis factor+++GO:0032496///response to lipopolysaccharide+++GO:0006536///glutamate metabolic process","inactive glutathione hydrolase 2","[GGT2_HUMAN|Reviewed]RecName: Full=Inactive glutathione hydrolase 2; AltName: Full=Gamma-glutamyltransferase 2; AltName: Full=Inactive gamma-glutamyltranspeptidase 2; Short=GGT 2; Flags: Precursor;+++[B5MCK8_HUMAN|Unreviewed]SubName: Full=Inactive glutathione hydrolase 2 {ECO:0000313|Ensembl:ENSP00000385601};"]
[102724200,"'LOC102724200'",6.35,14.47,11.22,10.68,{"$nulls":4},"GO:1990071///TRAPPII protein complex+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0034498///early endosome to Golgi transport","trafficking protein particle complex subunit 10-like","[A0A096LPH7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485615}; Flags: Fragment;"]
[102724219,"'LOC102724219'",178.8,82.05,76.59,112.48,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation","uncharacterized LOC102724219","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724250,"'LOC102724250'",424.71,372.71,320.23,372.55,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"neuroblastoma breakpoint family member 1","[NBPF1_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 1;+++[NBPF8_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 8;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFA_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 10;+++[NBPFB_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000305}; AltName: Full=Neuroblastoma breakpoint family member 24 {ECO:0000312|HGNC:HGNC:31993};+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFJ_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};"]
[102724279,"'LINC01835'",1,0,2,1,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"long intergenic non-protein coding RNA 1835","[CLC4G_HUMAN|diamond]RecName: Full=C-type lectin domain family 4 member G; AltName: Full=Liver and lymph node sinusoidal endothelial cell C-type lectin {ECO:0000303|PubMed:14711836}; Short=LSECtin {ECO:0000303|PubMed:14711836};+++[COL12_CHICK|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin-3; Short=CL-3; Short=cCL-3;+++[COL12_HUMAN|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; Short=hCL-P1; AltName: Full=Nurse cell scavenger receptor 2; AltName: Full=Scavenger receptor class A member 4; AltName: Full=Scavenger receptor with C-type lectin;+++[COL12_MOUSE|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; AltName: Full=Scavenger receptor with C-type lectin;+++[COL12_RAT|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; AltName: Full=Nurse cell scavenger receptor 2;"]
[102724378,"'LOC102724378'",10,8,1,6.33333333333333,{"$nulls":7},"uncharacterized LOC102724378"]
[102724428,"'SIK1B'",5143.44,6706,5718.99,5856.14333333333,"04922///Glucagon signaling pathway","H00606///Early infantile epileptic encephalopathy+++H01819///Early myoclonic encephalopathy",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0032870///cellular response to hormone stimulus","salt inducible kinase 1B (putative)","[SIK1B_HUMAN|Reviewed]RecName: Full=Probable serine/threonine-protein kinase SIK1B {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:P57059, ECO:0000255|PROSITE-ProRule:PRU00159}; AltName: Full=Salt-inducible kinase 1B {ECO:0000305};+++[SIK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase SIK1; EC=2.7.11.1 {ECO:0000269|PubMed:14976552, ECO:0000269|PubMed:18348280}; AltName: Full=Salt-inducible kinase 1; Short=SIK-1; AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 1; Short=Serine/threonine-protein kinase SNF1LK;"]
[102724474,"'LOC102724474'",11,21,10,14,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0031233///intrinsic component of external side of plasma membrane","GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0051897///positive regulation of protein kinase B signaling+++GO:0030335///positive regulation of cell migration+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007596///blood coagulation+++GO:0007598///blood coagulation, extrinsic pathway","WAS/WASL-interacting protein family member 2-like","[FA10_BOVIN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_HUMAN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; AltName: Full=Stuart-Prower factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_MOUSE|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RABIT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RAT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;"]
[102724488,"'LOC102724488'",16.27,24.23,9.15,16.55,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0019905///syntaxin binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding+++GO:0030276///clathrin binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0006906///vesicle fusion+++GO:0017158///regulation of calcium ion-dependent exocytosis","synaptotagmin-15","[SYT15_HUMAN|Reviewed]RecName: Full=Synaptotagmin-15; AltName: Full=Chr10Syt; AltName: Full=Synaptotagmin XV; Short=SytXV;+++[A0A096LNH4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000478933}; Flags: Fragment;+++[X6R8R1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-15 {ECO:0000313|Ensembl:ENSP00000363443};"]
[102724560,"'CBSL'",310.18,297.8,192.76,266.913333333333,"01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00270///Cysteine and methionine metabolism+++00260///Glycine, serine and threonine metabolism+++01230///Biosynthesis of amino acids","H00183///Homocystinuria","M00035///Methionine degradation+++M00338///Cysteine biosynthesis, homocysteine + serine => cysteine","R01290///L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)   L-Serine + L-Homocysteine <=> L-Cystathionine + H2O+++R04942///L-Serine hydro-lyase (adding homocysteine)   L-Serine + Selenohomocysteine <=> L-Selenocystathionine + H2O+++R00891///L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)   L-Serine + Hydrogen sulfide <=> L-Cysteine + H2O","GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016829///lyase activity+++GO:0004122///cystathionine beta-synthase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0004124///cysteine synthase activity+++GO:0020037///heme binding","GO:0008652///cellular amino acid biosynthetic process+++GO:0019344///cysteine biosynthetic process+++GO:0006535///cysteine biosynthetic process from serine+++GO:0019346///transsulfuration+++GO:0019343///cysteine biosynthetic process via cystathionine+++GO:0070814///hydrogen sulfide biosynthetic process+++GO:0050667///homocysteine metabolic process","cystathionine-beta-synthase like","[CBS_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase {ECO:0000305}; EC=4.2.1.22 {ECO:0000269|PubMed:20506325, ECO:0000269|PubMed:23974653, ECO:0000269|PubMed:23981774, ECO:0000269|PubMed:25044645}; AltName: Full=Beta-thionase; AltName: Full=Serine sulfhydrase;+++[CBSL_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase-like protein {ECO:0000305}; EC=4.2.1.22 {ECO:0000250|UniProtKB:P35520}; AltName: Full=Beta-thionase {ECO:0000250|UniProtKB:P35520}; AltName: Full=Serine sulfhydrase {ECO:0000250|UniProtKB:P35520};"]
[102724594,"'U2AF1L5'",2.99,65.68,0.75,23.14,"05131///Shigellosis+++03040///Spliceosome","H01481///Myelodysplastic syndrome (MDS)",null,null,"GO:0089701///U2AF+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0046872///metal ion binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0003723///RNA binding+++GO:0050733///RS domain binding+++GO:0003676///nucleic acid binding","GO:0000398///mRNA splicing, via spliceosome","U2 small nuclear RNA auxiliary factor 1 like 5","[U2AF1_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit; AltName: Full=U2 auxiliary factor 35 kDa subunit; AltName: Full=U2 small nuclear RNA auxiliary factor 1; AltName: Full=U2 snRNP auxiliary factor small subunit;+++[U2AF5_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000305}; AltName: Full=U2 small nuclear RNA auxiliary factor 1-like protein 5 {ECO:0000312|HGNC:HGNC:51830};+++[A0A1B0GW87_HUMAN|Unreviewed]SubName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000313|Ensembl:ENSP00000490825};"]
[102724624,"'LOC102724624'",0,0,2,0.666666666666667,{"$nulls":7},"uncharacterized protein ENSP00000382042-like","[YQ018_HUMAN|diamond]RecName: Full=Uncharacterized protein ENSP00000382033;+++[YQ019_HUMAN|diamond]RecName: Full=Uncharacterized protein ENSP00000382042;"]
[102724652,"'CRYAA2'",3,4,2,3,"04141///Protein processing in endoplasmic reticulum","H01202///Cataract",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050896///response to stimulus+++GO:0051260///protein homooligomerization+++GO:0032387///negative regulation of intracellular transport+++GO:0042026///protein refolding+++GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0007601///visual perception","crystallin alpha A2","[CRYA2_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A2 chain {ECO:0000305}; Contains: RecName: Full=Alpha-crystallin A2(1-172); Contains: RecName: Full=Alpha-crystallin A2(1-168); Contains: RecName: Full=Alpha-crystallin A2(1-162);+++[CRYAA_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A chain; AltName: Full=Heat shock protein beta-4; Short=HspB4; Contains: RecName: Full=Alpha-crystallin A(1-172); Contains: RecName: Full=Alpha-crystallin A(1-168); Contains: RecName: Full=Alpha-crystallin A(1-162);+++[A0A096LPJ9_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A2 chain {ECO:0000313|Ensembl:ENSP00000485653};+++[A0A140G952_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63592.1}; Flags: Fragment;+++[A0A140G954_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63594.1}; Flags: Fragment;+++[A0A140G955_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63595.1}; Flags: Fragment;+++[E7EWH7_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A chain {ECO:0000313|Ensembl:ENSP00000381201};+++[Q71V83_HUMAN|Unreviewed]SubName: Full=Alpha-A-crystallin {ECO:0000313|EMBL:AAB99912.1}; Flags: Fragment;"]
[102724720,"'LOC102724720'",1,0,1,0.666666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003839///gamma-glutamylcyclotransferase activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006750///glutathione biosynthetic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","uncharacterized LOC102724720","[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GGCT_HUMAN|diamond]RecName: Full=Gamma-glutamylcyclotransferase; EC=4.3.2.9; AltName: Full=Cytochrome c-releasing factor 21;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[102724751,"'LOC102724751'",73.49,71.8,86.98,77.4233333333333,"05200///Pathways in cancer+++05220///Chronic myeloid leukemia",{"$nulls":3},"GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0099092///postsynaptic density, intracellular component+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane","GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0050885///neuromuscular process controlling balance+++GO:0035023///regulation of Rho protein signal transduction+++GO:0071222///cellular response to lipopolysaccharide+++GO:0043314///negative regulation of neutrophil degranulation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050804///modulation of chemical synaptic transmission+++GO:0046777///protein autophosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0060268///negative regulation of respiratory burst+++GO:0002692///negative regulation of cellular extravasation+++GO:0065002///intracellular protein transmembrane transport+++GO:0050728///negative regulation of inflammatory response+++GO:0060313///negative regulation of blood vessel remodeling+++GO:0043547///positive regulation of GTPase activity+++GO:0050766///positive regulation of phagocytosis+++GO:0006468///protein phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0060216///definitive hemopoiesis+++GO:0051726///regulation of cell cycle+++GO:0043114///regulation of vascular permeability+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:0035556///intracellular signal transduction+++GO:0003014///renal system process+++GO:0048872///homeostasis of number of cells+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007420///brain development+++GO:0051171///regulation of nitrogen compound metabolic process","breakpoint cluster region protein-like","[ABR_BOVIN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_HUMAN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_MOUSE|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_XENTR|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[BCR_HUMAN|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1; AltName: Full=Renal carcinoma antigen NY-REN-26;+++[BCR_MOUSE|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1;"]
[102724770,"'LOC102724770'",234.36,192.55,233,219.97,"00330///Arginine and proline metabolism+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0031012///extracellular matrix+++GO:0005634///nucleus","GO:0004657///proline dehydrogenase activity","GO:0007155///cell adhesion+++GO:0009887///animal organ morphogenesis","protein DGCR6","[DGCR6_HUMAN|Reviewed]RecName: Full=Protein DGCR6; AltName: Full=DiGeorge syndrome critical region 6;+++[X5D7D2_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region 6 isoform D {ECO:0000313|EMBL:AHW56460.1}; Flags: Fragment;"]
[102724788,"'LOC102724788'",2686,1559,2062,2102.33333333333,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00330///Arginine and proline metabolism","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase   L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix","GO:0004657///proline dehydrogenase activity+++GO:0071949///FAD binding","GO:0019470///4-hydroxyproline catabolic process+++GO:0010133///proline catabolic process to glutamate+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0006562///proline catabolic process+++GO:0010942///positive regulation of cell death+++GO:0006560///proline metabolic process","proline dehydrogenase 1, mitochondrial","[PROD_BOVIN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000250|UniProtKB:O43272}; EC=1.5.5.2; AltName: Full=Proline oxidase {ECO:0000250|UniProtKB:O43272}; Flags: Precursor;+++[PROD_CAEEL|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;+++[PROD_DROME|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; AltName: Full=Protein sluggish-A; Flags: Precursor;+++[PROD_HUMAN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000305}; EC=1.5.5.2 {ECO:0000269|PubMed:15662599}; AltName: Full=Proline oxidase; AltName: Full=Proline oxidase 2; AltName: Full=p53-induced gene 6 protein; Flags: Precursor;+++[PROD_MOUSE|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;"]
[102724813,"'LOC102724813'",22,34,17,24.3333333333333,null,"H00591///Facioscapulohumeral muscular dystrophy (FSHD)",null,null,"GO:0015030///Cajal body+++GO:0005730///nucleolus+++GO:0030018///Z disc+++GO:0071013///catalytic step 2 spliceosome+++GO:0055120///striated muscle dense body","GO:0051015///actin filament binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006364///rRNA processing+++GO:0007517///muscle organ development","protein FRG1B","[FRG1_DROME|diamond]RecName: Full=Protein FRG1 homolog;+++[FRG1_HUMAN|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_MOUSE|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_TAKRU|diamond]RecName: Full=Protein FRG1;+++[FRG1_XENLA|diamond]RecName: Full=Protein FRG1 {ECO:0000250|UniProtKB:Q14331};"]
[102724843,"'LOC102724843'",361.23,235.26,217.85,271.446666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003677///DNA binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0006351///transcription, DNA-templated+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0043066///negative regulation of apoptotic process+++GO:0001933///negative regulation of protein phosphorylation","uncharacterized LOC102724843","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724951,"'LOC102724951'",76.98,108.42,59.02,81.4733333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005737///cytoplasm","GO:0004721///phosphoprotein phosphatase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0008284///positive regulation of cell proliferation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043066///negative regulation of apoptotic process","uncharacterized LOC102724951","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724965,"'LOC102724965'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC102724965","[A0A2Y9SDV6_PHYCD|diamond]SubName: Full=uncharacterized protein LOC102995166 {ECO:0000313|RefSeq:XP_023974475.1};"]
[102724984,"'LOC102724984'",3.91,4.2,4.72,4.27666666666667,{"$nulls":3},"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0030170///pyridoxal phosphate binding+++GO:0045296///cadherin binding+++GO:0016831///carboxy-lyase activity","GO:0019752///carboxylic acid metabolic process","KIAA2013 pseudogene","[K2013_BOVIN|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_HUMAN|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_MOUSE|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_XENLA|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_XENTR|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[PDXD1_BOVIN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_HUMAN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_MOUSE|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_XENLA|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD2_HUMAN|diamond]RecName: Full=Putative pyridoxal-dependent decarboxylase domain-containing protein 2; EC=4.1.1.-; AltName: Full=pyridoxal-dependent decarboxylase domain-containing 2 pseudogene;"]
[102724985,"'LOC102724985'",998.37,897.53,804.61,900.17,null,"H00542///Polycystic kidney disease+++H01728///Potter syndrome",null,"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0016328///lateral plasma membrane+++GO:0005654///nucleoplasm+++GO:0005929///cilium+++GO:0002133///polycystin complex+++GO:0016323///basolateral plasma membrane+++GO:0031514///motile cilium+++GO:0005887///integral component of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0060170///ciliary membrane+++GO:0030660///Golgi-associated vesicle membrane","GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0005262///calcium channel activity+++GO:0001042///RNA polymerase I core binding+++GO:0045296///cadherin binding+++GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0016831///carboxy-lyase activity+++GO:0044325///ion channel binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding","GO:0042254///ribosome biogenesis+++GO:0008344///adult locomotory behavior+++GO:0030010///establishment of cell polarity+++GO:0008283///cell proliferation+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0072177///mesonephric duct development+++GO:0007507///heart development+++GO:0021510///spinal cord development+++GO:0030155///regulation of cell adhesion+++GO:0006611///protein export from nucleus+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0021915///neural tube development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0072205///metanephric collecting duct development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043588///skin development+++GO:0048565///digestive tract development+++GO:0072164///mesonephric tubule development+++GO:0060236///regulation of mitotic spindle organization+++GO:0036303///lymph vessel morphogenesis+++GO:0001889///liver development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001502///cartilage condensation+++GO:0010976///positive regulation of neuron projection development+++GO:0051216///cartilage development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009653///anatomical structure morphogenesis+++GO:0034405///response to fluid shear stress+++GO:0007613///memory+++GO:0072237///metanephric proximal tubule development+++GO:0007160///cell-matrix adhesion+++GO:0019752///carboxylic acid metabolic process+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0007050///cell cycle arrest+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0001701///in utero embryonic development+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0070588///calcium ion transmembrane transport+++GO:0007259///JAK-STAT cascade+++GO:0048872///homeostasis of number of cells+++GO:0060674///placenta blood vessel development+++GO:0001822///kidney development+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007028///cytoplasm organization+++GO:0072218///metanephric ascending thin limb development+++GO:0001892///embryonic placenta development+++GO:0007000///nucleolus organization+++GO:0048806///genitalia development+++GO:0050982///detection of mechanical stimulus+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0060428///lung epithelium development+++GO:2000142///regulation of DNA-templated transcription, initiation+++GO:0032092///positive regulation of protein binding+++GO:0007204///positive regulation of cytosolic calcium ion concentration","pyridoxal-dependent decarboxylase domain-containing protein 1","[PDXD1_HUMAN|Reviewed]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[H3BND4_HUMAN|Unreviewed]SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000454791};+++[Q86XE2_HUMAN|Unreviewed]SubName: Full=PDXDC1 protein {ECO:0000313|EMBL:AAH45554.2}; SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000437835};"]
[102724993,"'LOC102724993'",597.23,517.63,554.6,556.486666666667,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0002133///polycystin complex+++GO:0060170///ciliary membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016323///basolateral plasma membrane+++GO:0009986///cell surface+++GO:0000139///Golgi membrane+++GO:0031514///motile cilium+++GO:0030660///Golgi-associated vesicle membrane+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm","GO:0019901///protein kinase binding+++GO:0030246///carbohydrate binding+++GO:0005262///calcium channel activity+++GO:0019904///protein domain specific binding+++GO:0044325///ion channel binding","GO:0036303///lymph vessel morphogenesis+++GO:0048565///digestive tract development+++GO:0043588///skin development+++GO:0001502///cartilage condensation+++GO:0032092///positive regulation of protein binding+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0072177///mesonephric duct development+++GO:0060674///placenta blood vessel development+++GO:0051216///cartilage development+++GO:0072218///metanephric ascending thin limb development+++GO:0060428///lung epithelium development+++GO:0072237///metanephric proximal tubule development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0007259///JAK-STAT cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0001701///in utero embryonic development+++GO:0072164///mesonephric tubule development+++GO:0030010///establishment of cell polarity+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0021915///neural tube development+++GO:0001892///embryonic placenta development+++GO:0048806///genitalia development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0015031///protein transport+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0021510///spinal cord development+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072205///metanephric collecting duct development+++GO:0060236///regulation of mitotic spindle organization+++GO:0034405///response to fluid shear stress+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0001822///kidney development+++GO:0007160///cell-matrix adhesion+++GO:0007507///heart development+++GO:0030155///regulation of cell adhesion+++GO:0050982///detection of mechanical stimulus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0001889///liver development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0007050///cell cycle arrest","nuclear pore complex-interacting protein family member A7-like","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;+++[NPIA1_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A1; AltName: Full=Nuclear pore complex-interacting protein; Short=NPIP;+++[NPIA2_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A2;+++[NPIA3_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A3;+++[NPIA5_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[NPIA7_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[PKD1_HUMAN|diamond]RecName: Full=Polycystin-1; Short=PC1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein; Flags: Precursor;+++[PKD1_MOUSE|diamond]RecName: Full=Polycystin-1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein homolog; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[102724994,"'LOC102724994'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"POM121 membrane glycoprotein pseudogene","[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;"]
[102724995,"'LOC102724995'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005764///lysosome","GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004566///beta-glucuronidase activity","GO:0007399///nervous system development+++GO:0001501///skeletal system development+++GO:0005975///carbohydrate metabolic process","POM121 membrane glycoprotein pseudogene","[BGLR_CANLF|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_CHLAE|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor; Fragment;+++[BGLR_FELCA|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_HUMAN|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; AltName: Full=Beta-G1; Flags: Precursor;+++[BGLR_PONAB|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[GUSP1_HUMAN|diamond]RecName: Full=Putative inactive beta-glucuronidase-like protein SMA3;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;"]
[102725009,"'LOC102725009'",50.07,38.01,30,39.36,{"$nulls":4},"GO:0005764///lysosome","GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0007399///nervous system development+++GO:0001501///skeletal system development","putative inactive beta-glucuronidase-like protein SMA3","[BGLR_CHLAE|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor; Fragment;+++[BGLR_FELCA|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_HUMAN|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; AltName: Full=Beta-G1; Flags: Precursor;+++[BGLR_PONAB|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[GUSP1_HUMAN|diamond]RecName: Full=Putative inactive beta-glucuronidase-like protein SMA3;"]
[10273,"'STUB1'",1461,1629,1917,1669,"04141///Protein processing in endoplasmic reticulum+++04120///Ubiquitin mediated proteolysis","H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0000151///ubiquitin ligase complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0030018///Z disc+++GO:0101031///chaperone complex+++GO:0005829///cytosol+++GO:0042405///nuclear inclusion body+++GO:0031371///ubiquitin conjugating enzyme complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0031072///heat shock protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0048156///tau protein binding+++GO:0030674///protein binding, bridging+++GO:0004842///ubiquitin-protein transferase activity+++GO:0051087///chaperone binding+++GO:0042803///protein homodimerization activity+++GO:0051879///Hsp90 protein binding+++GO:0019899///enzyme binding+++GO:0046332///SMAD binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0051787///misfolded protein binding+++GO:0030911///TPR domain binding+++GO:0001664///G protein-coupled receptor binding+++GO:0030544///Hsp70 protein binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0019900///kinase binding","GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0061684///chaperone-mediated autophagy+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0051604///protein maturation+++GO:0032091///negative regulation of protein binding+++GO:0071456///cellular response to hypoxia+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0034605///cellular response to heat+++GO:0031398///positive regulation of protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031943///regulation of glucocorticoid metabolic process+++GO:0002931///response to ischemia+++GO:0006281///DNA repair+++GO:0038128///ERBB2 signaling pathway+++GO:0031647///regulation of protein stability+++GO:0030968///endoplasmic reticulum unfolded protein response","STIP1 homology and U-box containing protein 1","[CHIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:11557750, ECO:0000269|PubMed:15466472}; AltName: Full=Antigen NY-CO-7 {ECO:0000303|PubMed:9610721}; AltName: Full=CLL-associated antigen KW-8 {ECO:0000303|PubMed:12200376}; AltName: Full=Carboxy terminus of Hsp70-interacting protein {ECO:0000303|PubMed:10330192}; AltName: Full=RING-type E3 ubiquitin transferase CHIP {ECO:0000305}; AltName: Full=STIP1 homology and U box-containing protein 1 {ECO:0000312|HGNC:HGNC:11427};+++[H3BS86_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000456591}; Flags: Fragment;+++[H3BTA3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457090}; Flags: Fragment;+++[H3BUD0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457583}; Flags: Fragment;+++[V9GYH3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000476751}; Flags: Fragment;"]
[10274,"'STAG1'",344,293,235,290.666666666667,"04113///Meiosis - yeast+++04110///Cell cycle+++04111///Cell cycle - yeast","H00773///Autosomal dominant mental retardation",null,null,"GO:0016363///nuclear matrix+++GO:0097431///mitotic spindle pole+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000775///chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006351///transcription, DNA-templated+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1901673///regulation of mitotic spindle assembly+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division","stromal antigen 1","[STAG1_HUMAN|Reviewed]RecName: Full=Cohesin subunit SA-1; AltName: Full=SCC3 homolog 1; AltName: Full=Stromal antigen 1;+++[Q4LE48_HUMAN|Unreviewed]SubName: Full=STAG1 variant protein {ECO:0000313|EMBL:BAE06105.1}; Flags: Fragment;"]
[10276,"'NET1'",158,156,123,145.666666666667,"04540///Gap junction+++04210///Apoptosis+++04530///Tight junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H00268///Lissencephaly (LIS)+++H00058///Amyotrophic lateral sclerosis (ALS)+++H00271///Polymicrogyria",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0005200///structural constituent of cytoskeleton+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0017049///GTP-Rho binding+++GO:0003924///GTPase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005525///GTP binding","GO:0035023///regulation of Rho protein signal transduction+++GO:0051451///myoblast migration+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0070301///cellular response to hydrogen peroxide+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0007017///microtubule-based process+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0001558///regulation of cell growth","neuroepithelial cell transforming 1","[ARHG8_HUMAN|Reviewed]RecName: Full=Neuroepithelial cell-transforming gene 1 protein; AltName: Full=Proto-oncogene p65 Net1; AltName: Full=Rho guanine nucleotide exchange factor 8;+++[Q5SQI5_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW86446.1}; SubName: Full=cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 protein {ECO:0000313|EMBL:BAG61338.1};+++[Q5SQI7_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_a {ECO:0000313|EMBL:EAW86445.1}; SubName: Full=cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA {ECO:0000313|EMBL:BAG37941.1};"]
[10277,"'UBE4B'",2006,1914,1567,1829,"04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0051117///ATPase binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0044257///cellular protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0051865///protein autoubiquitination+++GO:0034976///response to endoplasmic reticulum stress+++GO:0009411///response to UV+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0008626///granzyme-mediated apoptotic signaling pathway+++GO:0016567///protein ubiquitination+++GO:0006513///protein monoubiquitination+++GO:0031175///neuron projection development+++GO:0000209///protein polyubiquitination","ubiquitination factor E4B","[UBE4B_HUMAN|Reviewed]RecName: Full=Ubiquitin conjugation factor E4 B {ECO:0000305}; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q9ES00}; AltName: Full=Homozygously deleted in neuroblastoma 1 {ECO:0000312|EMBL:BAB40446.1}; AltName: Full=RING-type E3 ubiquitin transferase E4 B; AltName: Full=Ubiquitin fusion degradation protein 2 {ECO:0000312|EMBL:AAD02233.1};+++[B1AQ61_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000366358};+++[K7EP75_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000467258}; Flags: Fragment;+++[K7ERA7_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000468178}; Flags: Fragment;"]
[10278,"'EFS'",128,65,79,90.6666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0017124///SH3 domain binding","GO:0016477///cell migration+++GO:0035556///intracellular signal transduction+++GO:0090527///actin filament reorganization+++GO:0007155///cell adhesion","embryonal Fyn-associated substrate","[EFS_HUMAN|Reviewed]RecName: Full=Embryonal Fyn-associated substrate; Short=hEFS; AltName: Full=Cas scaffolding protein family member 3;"]
[10279,"'PRSS16'",51,37,40,42.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:0016020///membrane","GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis+++GO:0030163///protein catabolic process","serine protease 16","[TSSP_HUMAN|Reviewed]RecName: Full=Thymus-specific serine protease; EC=3.4.-.-; AltName: Full=Serine protease 16; Flags: Precursor;+++[B4DZV2_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000396589}; SubName: Full=cDNA FLJ52815, highly similar to Thymus-specific serine protease {ECO:0000313|EMBL:BAG64214.1};+++[C9JDN6_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419492};+++[F2Z2N5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000404349};+++[F8WBG5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418036};+++[F8WF25_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419437};+++[H0Y893_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418710}; Flags: Fragment;+++[H0Y8B9_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419538}; Flags: Fragment;"]
[1028,"'CDKN1C'",2317,1614,2355,2095.33333333333,"04110///Cell cycle","H01772///Adrenal hypoplasia congenita+++H00713///Beckwith-Wiedemann syndrome+++H00033///Adrenal carcinoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity","GO:0071514///genetic imprinting+++GO:0001501///skeletal system development+++GO:0035264///multicellular organism growth+++GO:0001822///kidney development+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0007049///cell cycle+++GO:0060065///uterus development+++GO:0007096///regulation of exit from mitosis+++GO:0033673///negative regulation of kinase activity+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0007050///cell cycle arrest+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042326///negative regulation of phosphorylation+++GO:0030099///myeloid cell differentiation+++GO:0055123///digestive system development+++GO:0043010///camera-type eye development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007568///aging+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0016310///phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001890///placenta development+++GO:0030325///adrenal gland development+++GO:0060669///embryonic placenta morphogenesis+++GO:0042551///neuron maturation+++GO:0007346///regulation of mitotic cell cycle","cyclin dependent kinase inhibitor 1C","[CDN1C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1C; AltName: Full=Cyclin-dependent kinase inhibitor p57; AltName: Full=p57Kip2;+++[A0A0G2JH30_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000321019};+++[A0A0G2JPX0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000484462};+++[A0A2R8YFP9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000496631};+++[A6NK88_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000370101};+++[B2D1N3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C transcript variant 3 {ECO:0000313|EMBL:ACB69757.1};"]
[10280,"'SIGMAR1'",3202,4180,4233,3871.66666666667,null,"H00856///Distal hereditary motor neuropathies (dHMN)+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0016021///integral component of membrane+++GO:0005640///nuclear outer membrane+++GO:0030426///growth cone+++GO:0014069///postsynaptic density+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005811///lipid droplet+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0004985///opioid receptor activity+++GO:0008144///drug binding","GO:0006869///lipid transport+++GO:0036474///cell death in response to hydrogen peroxide+++GO:0038003///opioid receptor signaling pathway+++GO:0070207///protein homotrimerization+++GO:0007399///nervous system development+++GO:0043523///regulation of neuron apoptotic process","sigma non-opioid intracellular receptor 1","[SGMR1_HUMAN|Reviewed]RecName: Full=Sigma non-opioid intracellular receptor 1; AltName: Full=Aging-associated gene 8 protein; AltName: Full=SR31747-binding protein; Short=SR-BP; AltName: Full=Sigma 1-type opioid receptor; Short=SIG-1R; Short=Sigma1-receptor; Short=Sigma1R; Short=hSigmaR1;+++[A2A3U5_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_d {ECO:0000313|EMBL:EAW58436.1}; SubName: Full=cDNA FLJ76396, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83781.1};+++[B4DR71_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57078, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61183.1};+++[Q5T1J1_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_c {ECO:0000313|EMBL:EAW58433.1}; SubName: Full=Sigma non-opioid intracellular receptor 1 {ECO:0000313|Ensembl:ENSP00000368170};"]
[102800317,"'TPTEP2-CSNK1E'",97.32,57.12,74.16,76.2,"04068///FoxO signaling pathway+++04711///Circadian rhythm - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species+++04710///Circadian rhythm+++04310///Wnt signaling pathway+++04391///Hippo signaling pathway - fly+++04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042752///regulation of circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0008360///regulation of cell shape+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway+++GO:0006281///DNA repair+++GO:0007165///signal transduction+++GO:0032197///transposition, RNA-mediated+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0006468///protein phosphorylation+++GO:1903827///regulation of cellular protein localization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1905426///positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation+++GO:0006897///endocytosis+++GO:0060070///canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006310///DNA recombination+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle","TPTEP2-CSNK1E readthrough","[KC1E_HUMAN|Reviewed]RecName: Full=Casein kinase I isoform epsilon; Short=CKI-epsilon; Short=CKIe; EC=2.7.11.1;+++[B3KRV2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34950 fis, clone NT2RP7017284, highly similar to Casein kinase I isoform epsilon {ECO:0000313|EMBL:BAG52514.1};+++[Q5U045_HUMAN|Unreviewed]SubName: Full=Casein kinase 1 epsilon {ECO:0000313|EMBL:ABM64212.1}; SubName: Full=Casein kinase 1, epsilon {ECO:0000313|EMBL:AAV38634.1}; SubName: Full=HCG2014051, isoform CRA_a {ECO:0000313|EMBL:EAW60228.1};"]
[10282,"'BET1'",152,129,123,134.666666666667,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0030173///integral component of Golgi membrane","GO:0005515///protein binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","Bet1 golgi vesicular membrane trafficking protein","[BET1_HUMAN|Reviewed]RecName: Full=BET1 homolog; Short=hBET1; AltName: Full=Golgi vesicular membrane-trafficking protein p18;+++[C9JTT8_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000413063};+++[H7C1N3_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000401260}; Flags: Fragment;+++[Q53XK0_HUMAN|Unreviewed]SubName: Full=BET1 homolog (S. cerevisiae) {ECO:0000313|EMBL:AAP88855.1}; SubName: Full=BET1 homolog (S. cerevisiae), isoform CRA_d {ECO:0000313|EMBL:EAW76803.1}; SubName: Full=cDNA, FLJ94635, Homo sapiens BET1 homolog (S. cerevisiae) (BET1), mRNA {ECO:0000313|EMBL:BAG36696.1};+++[Q68DU7_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000350125};"]
[10283,"'CWC27'",268,298,299,288.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0071012///catalytic step 1 spliceosome","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding","GO:0000413///protein peptidyl-prolyl isomerization+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006457///protein folding","CWC27 spliceosome associated protein homolog","[CWC27_HUMAN|Reviewed]RecName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000305}; AltName: Full=Antigen NY-CO-10 {ECO:0000303|PubMed:9610721}; AltName: Full=Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog {ECO:0000305|PubMed:20676357}; Short=PPIase CWC27 {ECO:0000305|PubMed:20676357}; AltName: Full=Serologically defined colon cancer antigen 10;+++[D6REK3_HUMAN|Unreviewed]SubName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000313|Ensembl:ENSP00000426802};"]
[10284,"'SAP18'",1080,1090,1192,1120.66666666667,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0000118///histone deacetylase complex+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0061574///ASAP complex","GO:0004407///histone deacetylase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity","GO:0008380///RNA splicing+++GO:0043065///positive regulation of apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0048025///negative regulation of mRNA splicing, via spliceosome","Sin3A associated protein 18","[SAP18_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP18; AltName: Full=18 kDa Sin3-associated polypeptide; AltName: Full=2HOR0202; AltName: Full=Cell growth-inhibiting gene 38 protein; AltName: Full=Sin3-associated polypeptide p18;+++[H7BZW6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000391846}; Flags: Fragment;+++[U3KPY7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475358}; Flags: Fragment;+++[U3KQ12_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475435}; Flags: Fragment;+++[X6RAL5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000371973};"]
[10285,"'SMNDC1'",200,205,220,208.333333333333,"03040///Spliceosome",{"$nulls":3},"GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0008380///RNA splicing+++GO:0006915///apoptotic process","survival motor neuron domain containing 1","[SPF30_HUMAN|Reviewed]RecName: Full=Survival of motor neuron-related-splicing factor 30; AltName: Full=30 kDa splicing factor SMNrp; AltName: Full=SMN-related protein; AltName: Full=Survival motor neuron domain-containing protein 1;"]
[10286,"'BCAS2'",392,447,441,426.666666666667,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005634///nucleus+++GO:0000974///Prp19 complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005813///centrosome+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005730///nucleolus","GO:0005515///protein binding","GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000375///RNA splicing, via transesterification reactions","BCAS2, pre-mRNA processing factor","[SPF27_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SPF27; AltName: Full=Breast carcinoma-amplified sequence 2; AltName: Full=DNA amplified in mammary carcinoma 1 protein; AltName: Full=Spliceosome-associated protein SPF 27;+++[B2R7W3_HUMAN|Unreviewed]SubName: Full=Breast carcinoma amplified sequence 2 {ECO:0000313|EMBL:BAG70059.1}; SubName: Full=Breast carcinoma amplified sequence 2, isoform CRA_a {ECO:0000313|EMBL:EAW56602.1}; SubName: Full=cDNA, FLJ93631, Homo sapiens breast carcinoma amplified sequence 2 (BCAS2), mRNA {ECO:0000313|EMBL:BAG35960.1};"]
[10287,"'RGS19'",138,193,204,178.333333333333,{"$nulls":4},"GO:0005903///brush border+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030136///clathrin-coated vesicle","GO:0001965///G-protein alpha-subunit binding+++GO:0005515///protein binding","GO:0007264///small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0045471///response to ethanol+++GO:0006914///autophagy","regulator of G protein signaling 19","[RGS19_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 19; Short=RGS19; AltName: Full=G-alpha-interacting protein; Short=GAIP;+++[B4DP94_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59828, highly similar to Regulator of G-protein signaling 19 {ECO:0000313|EMBL:BAG60506.1};+++[Q6I9S5_HUMAN|Unreviewed]SubName: Full=RGS19 protein {ECO:0000313|EMBL:CAG33711.1};+++[Q9H2T9_HUMAN|Unreviewed]SubName: Full=G alpha interacting protein {ECO:0000313|EMBL:AAG42352.1}; Flags: Fragment;"]
[10289,"'EIF1B'",441,408,394,414.333333333333,"03013///RNA transport",{"$nulls":3},"GO:0005575///cellular_component+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0043024///ribosomal small subunit binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006446///regulation of translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation","eukaryotic translation initiation factor 1B","[EIF1B_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1b; Short=eIF1b; AltName: Full=Protein translation factor SUI1 homolog GC20;+++[Q6FG85_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1B, isoform CRA_a {ECO:0000313|EMBL:EAW64598.1}; SubName: Full=GC20 protein {ECO:0000313|EMBL:CAG47019.1}; SubName: Full=cDNA, FLJ92189, Homo sapiens translation factor sui1 homolog (GC20), mRNA {ECO:0000313|EMBL:BAG34863.1}; Flags: Fragment;"]
[1029,"'CDKN2A'",8940,11461,12571,10990.6666666667,"04934///Cushing's syndrome+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++01524///Platinum drug resistance+++05214///Glioma+++05223///Non-small cell lung cancer+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05163///Human cytomegalovirus infection+++05212///Pancreatic cancer+++04218///Cellular senescence+++05219///Bladder cancer+++04110///Cell cycle+++05166///HTLV-I infection+++01522///Endocrine resistance+++05218///Melanoma+++05200///Pathways in cancer","H01513///Retinoblastoma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00054///Nasopharyngeal cancer+++H01556///Meningioma+++H00015///Malignant pleural mesothelioma+++H00042///Glioma+++H00008///Burkitt lymphoma+++H00040///Squamous cell carcinoma+++H00009///Adult T-cell leukemia+++H00017///Esophageal cancer+++H00014///Non-small cell lung cancer+++H00025///Penile cancer+++H00004///Chronic myeloid leukemia (CML)+++H00016///Oral cancer+++H01509///Tonsillar cancer+++H01464///Mantle cell lymphoma+++H00055///Laryngeal cancer+++H00047///Gallbladder cancer+++H00048///Hepatocellular carcinoma+++H01508///Salivary gland cancer+++H00046///Cholangiocarcinoma+++H00409///Type II diabetes mellitus+++H00038///Melanoma+++H00022///Bladder cancer+++H00019///Pancreatic cancer",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035985///senescence-associated heterochromatin focus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0003723///RNA binding+++GO:0055105///ubiquitin-protein transferase inhibitor activity+++GO:0097718///disordered domain specific binding+++GO:0019901///protein kinase binding+++GO:0051059///NF-kappaB binding+++GO:1990948///ubiquitin ligase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0003677///DNA binding+++GO:0002039///p53 binding+++GO:0019789///SUMO transferase activity+++GO:0016301///kinase activity","GO:0050821///protein stabilization+++GO:0090399///replicative senescence+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0033235///positive regulation of protein sumoylation+++GO:0042326///negative regulation of phosphorylation+++GO:0000422///autophagy of mitochondrion+++GO:0046825///regulation of protein export from nucleus+++GO:0030889///negative regulation of B cell proliferation+++GO:0000209///protein polyubiquitination+++GO:2000435///negative regulation of protein neddylation+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0016925///protein sumoylation+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007265///Ras protein signal transduction+++GO:0007050///cell cycle arrest+++GO:0051882///mitochondrial depolarization+++GO:0071158///positive regulation of cell cycle arrest+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0031648///protein destabilization+++GO:0016310///phosphorylation+++GO:0008637///apoptotic mitochondrial changes+++GO:0048103///somatic stem cell division+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0090398///cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0030308///negative regulation of cell growth+++GO:1902510///regulation of apoptotic DNA fragmentation+++GO:0006469///negative regulation of protein kinase activity+++GO:0070534///protein K63-linked ubiquitination+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:1903051///negative regulation of proteolysis involved in cellular protein catabolic process+++GO:2000774///positive regulation of cellular senescence+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006915///apoptotic process+++GO:1990000///amyloid fibril formation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0031647///regulation of protein stability+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:2000111///positive regulation of macrophage apoptotic process+++GO:0006364///rRNA processing+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","cyclin dependent kinase inhibitor 2A","[ARF_HUMAN|Reviewed]RecName: Full=Tumor suppressor ARF {ECO:0000305}; AltName: Full=Alternative reading frame {ECO:0000303|PubMed:9724636}; Short=ARF {ECO:0000303|PubMed:9724636}; AltName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=p14ARF {ECO:0000303|PubMed:9724636};+++[CDN2A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=Cyclin-dependent kinase 4 inhibitor A; Short=CDK4I; AltName: Full=Multiple tumor suppressor 1; Short=MTS-1; AltName: Full=p16-INK4a; Short=p16-INK4; Short=p16INK4A;+++[A7LNE7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:ABS32187.1}; Flags: Fragment;+++[D1LYX3_HUMAN|Unreviewed]SubName: Full=Truncated tumor suppressor protein P16 {ECO:0000313|EMBL:ACY78326.1};+++[J3QRG6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000464202};+++[K7ENC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000466887};+++[K7ES20_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000468510};+++[K7PML8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AFN61600.1};+++[L8E941_HUMAN|Unreviewed]SubName: Full=Alternative protein CDKN2A {ECO:0000313|EMBL:CCQ43815.1};+++[Q208B5_HUMAN|Unreviewed]SubName: Full=p16 {ECO:0000313|EMBL:ABD72255.1}; Flags: Fragment;+++[Q2MJK0_HUMAN|Unreviewed]SubName: Full=p16 protein {ECO:0000313|EMBL:ABC50001.1}; Flags: Fragment;+++[Q5ZEY9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:CAH59950.1}; Flags: Fragment;+++[Q9UPB7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AAD02319.1}; Flags: Fragment;"]
[10290,"'SPEG'",1902,2669,2384,2318.33333333333,null,"H00700///Centronuclear myopathy",null,null,"GO:0005634///nucleus","GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0072358///cardiovascular system development+++GO:0030154///cell differentiation+++GO:0016310///phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0042692///muscle cell differentiation+++GO:0007517///muscle organ development","SPEG complex locus","[SPEG_HUMAN|Reviewed]RecName: Full=Striated muscle preferentially expressed protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[B9ZVR7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000379926};+++[C9J8D8_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000410986}; Flags: Fragment;+++[C9JWU5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000393134}; Flags: Fragment;+++[F8WCA7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000406530};+++[G5E9J7_HUMAN|Unreviewed]SubName: Full=Aortic preferentially expressed gene 1, isoform CRA_i {ECO:0000313|EMBL:EAW70750.1}; SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000397514};+++[H0Y3W0_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000387344}; Flags: Fragment;+++[H7BZM6_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000390353}; Flags: Fragment;+++[H7C3Y5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000414549}; Flags: Fragment;"]
[10291,"'SF3A1'",3550,3635,3564,3583,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0005684///U2-type spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005686///U2 snRNP+++GO:0071004///U2-type prespliceosome+++GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000389///mRNA 3'-splice site recognition","splicing factor 3a subunit 1","[SF3A1_HUMAN|Reviewed]RecName: Full=Splicing factor 3A subunit 1; AltName: Full=SF3a120; AltName: Full=Spliceosome-associated protein 114; Short=SAP 114;+++[A0A024R1K8_HUMAN|Unreviewed]SubName: Full=Splicing factor 3a, subunit 1, 120kDa, isoform CRA_a {ECO:0000313|EMBL:EAW59879.1};+++[F8WB66_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000397267};+++[F8WC79_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000412715};+++[H7C1L2_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000400862}; Flags: Fragment;"]
[10293,"'TRAIP'",23,27,33,27.6666666666667,null,"H00992///Seckel syndrome",null,null,"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0016567///protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0008283///cell proliferation+++GO:0032688///negative regulation of interferon-beta production+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway","TRAF interacting protein","[TRAIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRAIP; EC=2.3.2.27; AltName: Full=RING finger protein 206; AltName: Full=RING-type E3 ubiquitin transferase TRAIP {ECO:0000305}; AltName: Full=TRAF-interacting protein;+++[E7EN91_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000418544}; Flags: Fragment;+++[E7ETV1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000420085};+++[E7EVC4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419556};+++[E7EW89_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419350}; Flags: Fragment;"]
[10294,"'DNAJA2'",754,812,713,759.666666666667,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0001671///ATPase activator activity+++GO:0031072///heat shock protein binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006457///protein folding+++GO:0042026///protein refolding+++GO:0008284///positive regulation of cell proliferation+++GO:0009408///response to heat+++GO:0032781///positive regulation of ATPase activity","DnaJ heat shock protein family (Hsp40) member A2","[DNJA2_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily A member 2; AltName: Full=Cell cycle progression restoration gene 3 protein; AltName: Full=Dnj3; Short=Dj3; AltName: Full=HIRA-interacting protein 4; AltName: Full=Renal carcinoma antigen NY-REN-14; Flags: Precursor;+++[A0A024R6S1_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily A, member 2, isoform CRA_a {ECO:0000313|EMBL:EAW82694.1};+++[A0A087WT48_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000477579}; Flags: Fragment;+++[I3L320_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000460104};"]
[10295,"'BCKDK'",1746,1774,1978,1832.66666666667,null,"H02136///Branched-chain ketoacid dehydrogenase kinase deficiency",null,null,"GO:0005947///mitochondrial alpha-ketoglutarate dehydrogenase complex+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0047323///[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0009083///branched-chain amino acid catabolic process+++GO:0009063///cellular amino acid catabolic process","branched chain ketoacid dehydrogenase kinase","[BCKD_HUMAN|Reviewed]RecName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; EC=2.7.11.4; AltName: Full=Branched-chain alpha-ketoacid dehydrogenase kinase; Short=BCKD-kinase; Short=BCKDHKIN; Flags: Precursor;+++[A0A024QZA9_HUMAN|Unreviewed]SubName: Full=Branched chain ketoacid dehydrogenase kinase, isoform CRA_b {ECO:0000313|EMBL:EAW52162.1};+++[H3BNP3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000454947}; Flags: Fragment;+++[H3BQP2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000455866}; Flags: Fragment;+++[H3BS02_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456479};+++[H3BTL2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457226}; Flags: Fragment;+++[H3BUV3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457821}; Flags: Fragment;"]
[10296,"'MAEA'",1231,1362,1417,1336.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0034657///GID complex+++GO:0005826///actomyosin contractile ring+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix","GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0003779///actin binding","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045721///negative regulation of gluconeogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048821///erythrocyte development+++GO:0043249///erythrocyte maturation+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0048822///enucleate erythrocyte development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007155///cell adhesion","macrophage erythroblast attacher","[MAEA_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein transferase MAEA; EC=2.3.2.27 {ECO:0000269|PubMed:29911972}; AltName: Full=Cell proliferation-inducing gene 5 protein {ECO:0000303|Ref.1}; AltName: Full=Erythroblast macrophage protein {ECO:0000303|PubMed:9763581}; AltName: Full=Human lung cancer oncogene 10 protein; Short=HLC-10; AltName: Full=Macrophage erythroblast attacher; AltName: Full=P44EMLP {ECO:0000303|PubMed:17467196};+++[B3KRN7_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_c {ECO:0000313|EMBL:EAW82589.1}; SubName: Full=cDNA FLJ34632 fis, clone KIDNE2015660, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG52449.1};+++[B4DJP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54833, moderately similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG58910.1};+++[B4DQT1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000424436}; SubName: Full=cDNA FLJ53639, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61043.1};+++[B4DVN3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000426807}; SubName: Full=cDNA FLJ54556, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62745.1};+++[D3DVP1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_b {ECO:0000313|EMBL:EAW82591.1};+++[D3DVP3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_a {ECO:0000313|EMBL:EAW82588.1};+++[D3DVP6_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_d {ECO:0000313|EMBL:EAW82592.1};+++[D6R8Z3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422235};+++[D6RA86_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000423056};+++[D6RDW4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426966};+++[D6RE80_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426903}; Flags: Fragment;+++[D6REW7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000421644}; Flags: Fragment;+++[D6RIB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427512};+++[D6RID6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427460}; Flags: Fragment;+++[E7ESC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422215};"]
[10297,"'APC2'",1345,689,849,961,"05224///Breast cancer+++04390///Hippo signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05213///Endometrial cancer+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04810///Regulation of actin cytoskeleton+++05206///MicroRNAs in cancer+++04310///Wnt signaling pathway+++05165///Human papillomavirus infection+++05166///HTLV-I infection+++04550///Signaling pathways regulating pluripotency of stem cells+++05210///Colorectal cancer+++05225///Hepatocellular carcinoma","H02049///Bilateral macronodular adrenal hyperplasia (BMAH)+++H00017///Esophageal cancer+++H00020///Colorectal cancer+++H00044///Cancer of the anal canal+++H01431///Cushing's syndrome+++H01667///Medulloblastoma+++H01025///Familial adenomatous polyposis+++H00018///Gastric cancer+++H00047///Gallbladder cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030496///midbody+++GO:0015630///microtubule cytoskeleton+++GO:0031258///lamellipodium membrane+++GO:0005884///actin filament+++GO:0045171///intercellular bridge+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0016342///catenin complex+++GO:0016020///membrane","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0008017///microtubule binding+++GO:0008013///beta-catenin binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0090630///activation of GTPase activity+++GO:0006413///translational initiation+++GO:0000226///microtubule cytoskeleton organization+++GO:0006364///rRNA processing+++GO:0001649///osteoblast differentiation+++GO:0016055///Wnt signaling pathway+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0042274///ribosomal small subunit biogenesis","APC2, WNT signaling pathway regulator","[APCL_HUMAN|Reviewed]RecName: Full=Adenomatous polyposis coli protein 2; AltName: Full=Adenomatous polyposis coli protein-like; Short=APC-like;"]
[10298,"'PAK4'",2748,2678,2943,2789.66666666667,"04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++04012///ErbB signaling pathway+++04360///Axon guidance+++04660///T cell receptor signaling pathway+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005925///focal adhesion+++GO:0005913///cell-cell adherens junction+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0048365///Rac GTPase binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045766///positive regulation of angiogenesis+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0001558///regulation of cell growth+++GO:0006915///apoptotic process+++GO:0006468///protein phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0071407///cellular response to organic cyclic compound+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0060996///dendritic spine development+++GO:0023014///signal transduction by protein phosphorylation+++GO:0098609///cell-cell adhesion+++GO:0016477///cell migration+++GO:0043408///regulation of MAPK cascade+++GO:0016310///phosphorylation","p21 (RAC1) activated kinase 4","[PAK4_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 4; EC=2.7.11.1; AltName: Full=p21-activated kinase 4; Short=PAK-4;+++[A0A024R0J1_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[A0A024R0L8_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[B4DUG0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61413, highly similar to Serine/threonine-protein kinase PAK 4 {ECO:0000313|EMBL:BAG62322.1}; SubName: Full=p21(CDKN1A)-activated kinase 4, isoform CRA_e {ECO:0000313|EMBL:EAW56865.1};+++[M0R0L9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000471318}; Flags: Fragment;+++[M0R1R1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472061}; Flags: Fragment;+++[M0R2X4_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472862}; Flags: Fragment;+++[M0R3G6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000473215}; Flags: Fragment;"]
[10299,"'MARCH6'",1506,1396,1143,1348.33333333333,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0000835///ER ubiquitin ligase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0008270///zinc ion binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0061630///ubiquitin protein ligase activity","GO:0016567///protein ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0010498///proteasomal protein catabolic process+++GO:0036503///ERAD pathway+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:1904380///endoplasmic reticulum mannose trimming","membrane associated ring-CH-type finger 6","[MARH6_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MARCH6; EC=2.3.2.27; AltName: Full=Doa10 homolog; AltName: Full=Membrane-associated RING finger protein 6; AltName: Full=Membrane-associated RING-CH protein VI; Short=MARCH-VI; AltName: Full=Protein TEB-4; AltName: Full=RING finger protein 176; AltName: Full=RING-type E3 ubiquitin transferase MARCH6 {ECO:0000305};+++[A0A0B4J206_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000424512};+++[D6RHY7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000426000};"]
[103,"'ADAR'",6477,6622,5874,6324.33333333333,"05162///Measles+++05164///Influenza A+++04623///Cytosolic DNA-sensing pathway","H00880///Dyschromatosis symmetrica hereditaria",null,null,"GO:0005634///nucleus+++GO:0044530///supraspliceosomal complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0003677///DNA binding+++GO:0003725///double-stranded RNA binding","GO:0006397///mRNA processing+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0016553///base conversion or substitution editing+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0006611///protein export from nucleus+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006396///RNA processing+++GO:0006606///protein import into nucleus+++GO:0006382///adenosine to inosine editing+++GO:0009615///response to virus+++GO:0035455///response to interferon-alpha+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060337///type I interferon signaling pathway+++GO:0031054///pre-miRNA processing+++GO:0031047///gene silencing by RNA","adenosine deaminase, RNA specific","[DSRAD_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific adenosine deaminase; Short=DRADA {ECO:0000303|PubMed:7972084}; EC=3.5.4.37 {ECO:0000269|PubMed:7565688, ECO:0000269|PubMed:7972084}; AltName: Full=136 kDa double-stranded RNA-binding protein; Short=p136; AltName: Full=Interferon-inducible protein 4; Short=IFI-4; AltName: Full=K88DSRBP;+++[A2IBT1_HUMAN|Unreviewed]SubName: Full=Truncated adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73519.1};+++[A2IBT2_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73520.1}; Flags: Fragment;+++[D3DV75_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase, RNA-specific, isoform CRA_b {ECO:0000313|EMBL:EAW53189.1};+++[H0YCK3_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific adenosine deaminase {ECO:0000313|Ensembl:ENSP00000431794}; Flags: Fragment;"]
[1030,"'CDKN2B'",7107,9682,7812,8200.33333333333,"04934///Cushing's syndrome+++04110///Cell cycle+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05166///HTLV-I infection+++04068///FoxO signaling pathway+++05226///Gastric cancer+++05222///Small cell lung cancer+++04350///TGF-beta signaling pathway+++04218///Cellular senescence","H00015///Malignant pleural mesothelioma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00409///Type II diabetes mellitus+++H01556///Meningioma",null,null,"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0016301///kinase activity","GO:0030219///megakaryocyte differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0031668///cellular response to extracellular stimulus+++GO:0016310///phosphorylation+++GO:0090398///cellular senescence+++GO:0007093///mitotic cell cycle checkpoint+++GO:0008285///negative regulation of cell proliferation+++GO:0048536///spleen development+++GO:0031670///cellular response to nutrient+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0042326///negative regulation of phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway","cyclin dependent kinase inhibitor 2B","[CDN2B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor B; AltName: Full=Multiple tumor suppressor 2; Short=MTS-2; AltName: Full=p14-INK4b; AltName: Full=p15-INK4b; Short=p15INK4B;+++[K7PPU3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AFN61601.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4), isoform CRA_b {ECO:0000313|EMBL:EAW58597.1}; SubName: Full=p15 {ECO:0000313|EMBL:AGC10270.1};+++[Q5ZEY8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:CAH59951.1};+++[Q8NIA6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AAF28397.1}; Flags: Fragment;"]
[10300,"'KATNB1'",728,730,749,735.666666666667,null,"H00268///Lissencephaly (LIS)",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0030426///growth cone+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0030496///midbody+++GO:0005819///spindle+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0008352///katanin complex+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0030424///axon","GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0070840///dynein complex binding","GO:0051301///cell division+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0010942///positive regulation of cell death+++GO:0007019///microtubule depolymerization+++GO:0007049///cell cycle+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0051013///microtubule severing+++GO:0006605///protein targeting+++GO:0010976///positive regulation of neuron projection development","katanin regulatory subunit B1","[KTNB1_HUMAN|Reviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000255|HAMAP-Rule:MF_03022};+++[A0A024R6U1_HUMAN|Unreviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000256|HAMAP-Rule:MF_03022};+++[H3BPD8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455270}; Flags: Fragment;+++[H3BPK1_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455350}; Flags: Fragment;+++[H3BT67_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457046}; Flags: Fragment;+++[H3BTU7_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457334}; Flags: Fragment;+++[H3BTV8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457347}; Flags: Fragment;"]
[10302,"'SNAPC5'",132,143,158,144.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0006355///regulation of transcription, DNA-templated","small nuclear RNA activating complex polypeptide 5","[SNPC5_HUMAN|Reviewed]RecName: Full=snRNA-activating protein complex subunit 5; Short=SNAPc subunit 5; AltName: Full=Small nuclear RNA-activating complex polypeptide 5; AltName: Full=snRNA-activating protein complex 19 kDa subunit; Short=SNAPc 19 kDa subunit;+++[A0A024R5X1_HUMAN|Unreviewed]SubName: Full=Small nuclear RNA activating complex, polypeptide 5, 19kDa, isoform CRA_a {ECO:0000313|EMBL:EAW77772.1};+++[H3BQA0_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000455680};+++[H3BSI3_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000456716};"]
[10307,"'APBB3'",154,165,191,170,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated","amyloid beta precursor protein binding family B member 3","[APBB3_HUMAN|Reviewed]RecName: Full=Amyloid-beta A4 precursor protein-binding family B member 3; AltName: Full=Protein Fe65-like 2; Short=Fe65L2;+++[B3KQG2_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3, isoform CRA_b {ECO:0000313|EMBL:EAW62042.1}; SubName: Full=cDNA FLJ43254 fis, clone HEART2008108, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG54172.1}; SubName: Full=cDNA FLJ90404 fis, clone NT2RP2006092, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG52024.1};+++[D6RBA1_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000424317};+++[D6RJB2_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000427272};+++[E7EX91_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000351389};+++[Q59EH2_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein-binding, family B, member 3 isoform b variant {ECO:0000313|EMBL:BAD93076.1}; Flags: Fragment;+++[Q86Z13_HUMAN|Unreviewed]SubName: Full=Fe65L2 isoform 339 {ECO:0000313|EMBL:BAC56948.1};+++[Q96DX9_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3 {ECO:0000313|EMBL:AAH13158.1};"]
[10308,"'ZNF267'",72,41,71,61.3333333333333,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 267","[ZN267_HUMAN|Reviewed]RecName: Full=Zinc finger protein 267; AltName: Full=Zinc finger protein HZF2;+++[H3BMG2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454369}; Flags: Fragment;+++[H3BNA3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454753}; Flags: Fragment;+++[H3BPW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000455493}; Flags: Fragment;+++[I3L4I6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000461286};"]
[10309,"'CCNO'",1065,697,880,880.666666666667,null,"H00564///Primary ciliary dyskinesia",null,null,"GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity","GO:0045787///positive regulation of cell cycle+++GO:0060271///cilium assembly+++GO:0000278///mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042493///response to drug+++GO:1903251///multi-ciliated epithelial cell differentiation+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0006468///protein phosphorylation+++GO:0030030///cell projection organization+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division","cyclin O","[CCNO_HUMAN|Reviewed]RecName: Full=Cyclin-O;"]
[1031,"'CDKN2C'",6,4,5,5,"01522///Endocrine resistance+++04934///Cushing's syndrome+++04110///Cell cycle+++05202///Transcriptional misregulation in cancer+++05166///HTLV-I infection",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0019901///protein kinase binding","GO:0016310///phosphorylation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0042326///negative regulation of phosphorylation+++GO:0007049///cell cycle+++GO:0048709///oligodendrocyte differentiation+++GO:0007050///cell cycle arrest+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0008285///negative regulation of cell proliferation","cyclin dependent kinase inhibitor 2C","[CDN2C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor C; AltName: Full=Cyclin-dependent kinase 6 inhibitor; AltName: Full=p18-INK4c; AltName: Full=p18-INK6;+++[Q6ICV4_HUMAN|Unreviewed]SubName: Full=CDKN2C protein {ECO:0000313|EMBL:CAG29285.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2C (P18, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAX06833.1}; SubName: Full=cDNA FLJ33851 fis, clone CTONG2005635, highly similar to CYCLIN-DEPENDENT KINASE 6 INHIBITOR {ECO:0000313|EMBL:BAG52297.1}; Flags: Fragment;+++[Q9P1T2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2C {ECO:0000313|EMBL:AAF28398.1}; Flags: Fragment;"]
[10311,"'VPS26C'",633,576,524.5,577.833333333333,{"$nulls":4},"GO:0005768///endosome+++GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0008565///protein transporter activity","GO:0008150///biological_process+++GO:0006886///intracellular protein transport","VPS26 endosomal protein sorting factor C","[DSCR3_HUMAN|Reviewed]RecName: Full=Down syndrome critical region protein 3; AltName: Full=Down syndrome critical region protein A;+++[A8MTY9_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381964};+++[A8MY26_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381967}; SubName: Full=cDNA FLJ53689, highly similar to Down syndrome critical region protein 3 {ECO:0000313|EMBL:BAH14000.1};"]
[10312,"'TCIRG1'",515,670,627,604,"04721///Synaptic vesicle cycle+++05323///Rheumatoid arthritis+++05152///Tuberculosis+++04145///Phagosome+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04142///Lysosome+++00190///Oxidative phosphorylation+++04966///Collecting duct acid secretion+++01100///Metabolic pathways+++05110///Vibrio cholerae infection+++05165///Human papillomavirus infection","H00557///Cutis laxa+++H00428///Distal renal tubular acidosis (RTA type 1)+++H00436///Osteopetrosis","M00160///V-type ATPase, eukaryotes",null,"GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0005886///plasma membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030670///phagocytic vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0010008///endosome membrane+++GO:0005765///lysosomal membrane","GO:0051117///ATPase binding+++GO:0005215///transporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism","GO:0007035///vacuolar acidification+++GO:0006811///ion transport+++GO:0016236///macroautophagy+++GO:1902600///proton transmembrane transport+++GO:0006968///cellular defense response+++GO:0033572///transferrin transport+++GO:0034220///ion transmembrane transport+++GO:0007039///protein catabolic process in the vacuole+++GO:0043312///neutrophil degranulation+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0015991///ATP hydrolysis coupled proton transport","T cell immune regulator 1, ATPase H+ transporting V0 subunit a3","[VPP3_HUMAN|Reviewed]RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 3; Short=V-ATPase 116 kDa isoform a3; AltName: Full=Osteoclastic proton pump 116 kDa subunit; Short=OC-116 kDa; Short=OC116; AltName: Full=T-cell immune regulator 1; AltName: Full=T-cell immune response cDNA7 protein; Short=TIRC7; AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3;+++[A0A024R5E5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PM12_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[E9PMC5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PNA6_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YCE3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YEL3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q64F87_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN4_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 8 {ECO:0000313|EMBL:AAS59838.1}; Flags: Fragment;+++[Q6QBN5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN6_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 6 {ECO:0000313|EMBL:AAS59836.1}; Flags: Fragment;+++[Q6QBN7_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN8_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q8TCH1_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;"]
[10313,"'RTN3'",1908,1847,1704,1819.66666666667,"05010///Alzheimer's disease",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0071786///endoplasmic reticulum tubular network organization+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:0016032///viral process+++GO:0016192///vesicle-mediated transport+++GO:0006915///apoptotic process","reticulon 3","[RTN3_HUMAN|Reviewed]RecName: Full=Reticulon-3; AltName: Full=Homolog of ASY protein; Short=HAP; AltName: Full=Neuroendocrine-specific protein-like 2; Short=NSP-like protein 2; AltName: Full=Neuroendocrine-specific protein-like II; Short=NSP-like protein II; Short=NSPLII;+++[A0A024R5C4_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[B7Z4M1_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[F5GWG7_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000441614}; Flags: Fragment;+++[F5H617_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[F5H891_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000442080}; Flags: Fragment;+++[Q7RTN4_HUMAN|Unreviewed]SubName: Full=Truncated RTN3-A3 {ECO:0000313|EMBL:DAA01930.1};"]
[10314,"'LANCL1'",458,506,368,444,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0017124///SH3 domain binding+++GO:0008270///zinc ion binding+++GO:0043295///glutathione binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway","LanC like 1","[LANC1_HUMAN|Reviewed]RecName: Full=LanC-like protein 1; AltName: Full=40 kDa erythrocyte membrane protein; Short=p40;+++[A0A024R3Z5_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_b {ECO:0000313|EMBL:EAW70491.1};+++[B2R602_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92709, highly similar to Homo sapiens LanC lantibiotic synthetase component C-like 1 (bacterial) (LANCL1), mRNA {ECO:0000313|EMBL:BAG35299.1};+++[E9PHS0_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000396518}; Flags: Fragment;+++[F8WDS9_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000395442};+++[H7C2E3_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000405364}; Flags: Fragment;+++[Q53TN2_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_a {ECO:0000313|EMBL:EAW70487.1};+++[Q6FHH6_HUMAN|Unreviewed]SubName: Full=LANCL1 protein {ECO:0000313|EMBL:CAG46576.1}; Flags: Fragment;"]
[10316,"'NMUR1'",13,6,3,7.33333333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0001607///neuromedin U receptor activity+++GO:0042924///neuromedin U binding","GO:0007202///activation of phospholipase C activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006816///calcium ion transport+++GO:0007165///signal transduction+++GO:0048016///inositol phosphate-mediated signaling+++GO:0006939///smooth muscle contraction+++GO:0019722///calcium-mediated signaling+++GO:0007218///neuropeptide signaling pathway+++GO:0006821///chloride transport","neuromedin U receptor 1","[NMUR1_HUMAN|Reviewed]RecName: Full=Neuromedin-U receptor 1; Short=NMU-R1; AltName: Full=G-protein coupled receptor 66; AltName: Full=G-protein coupled receptor FM-3;+++[L8E9D8_HUMAN|Unreviewed]SubName: Full=Alternative protein NMUR1 {ECO:0000313|EMBL:CCQ43346.1};"]
[10317,"'B3GALT5'",34,35,10,26.3333333333333,"01100///Metabolic pathways+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,"M00070///Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer","R05964///UDP-D-galactose + Globoside <=> UDP + Galactosylgloboside+++R06006///UDP-D-galactose + Lc3Cer <=> UDP + Lc4Cer","GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity","GO:0009312///oligosaccharide biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006486///protein glycosylation+++GO:0009617///response to bacterium","beta-1,3-galactosyltransferase 5","[B3GT5_HUMAN|Reviewed]RecName: Full=Beta-1,3-galactosyltransferase 5; Short=Beta-1,3-GalTase 5; Short=Beta3Gal-T5; Short=Beta3GalT5; Short=b3Gal-T5; EC=2.4.1.-; AltName: Full=Beta-3-Gx-T5; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5;+++[A0A0A0MS93_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};"]
[10318,"'TNIP1'",2160.97,2298,2402.78,2287.25,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0070034///telomerase RNA binding+++GO:0005515///protein binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0003723///RNA binding","GO:0043489///RNA stabilization+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0051973///positive regulation of telomerase activity+++GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0050727///regulation of inflammatory response+++GO:0006364///rRNA processing+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:0042254///ribosome biogenesis+++GO:0045071///negative regulation of viral genome replication+++GO:0006954///inflammatory response+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000493///box H/ACA snoRNP assembly+++GO:0001522///pseudouridine synthesis+++GO:0009101///glycoprotein biosynthetic process+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007159///leukocyte cell-cell adhesion+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0085032///modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade+++GO:0006952///defense response+++GO:1905323///telomerase holoenzyme complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090669///telomerase RNA stabilization+++GO:0050729///positive regulation of inflammatory response+++GO:0006412///translation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016579///protein deubiquitination","TNFAIP3 interacting protein 1","[TNIP1_HUMAN|Reviewed]RecName: Full=TNFAIP3-interacting protein 1; AltName: Full=A20-binding inhibitor of NF-kappa-B activation 1; Short=ABIN-1; AltName: Full=HIV-1 Nef-interacting protein; AltName: Full=Nef-associated factor 1; Short=Naf1; AltName: Full=Nip40-1; AltName: Full=Virion-associated nuclear shuttling protein; Short=VAN; Short=hVAN;+++[A0A0A0MRZ4_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000374029};+++[A8K4N4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77844, highly similar to Homo sapiens TNFAIP3 interacting protein 1, mRNA {ECO:0000313|EMBL:BAF83688.1};+++[B7Z8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61022, highly similar to Nef-associated factor 1 {ECO:0000313|EMBL:BAH13988.1};+++[E7EMV7_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427854};+++[E7EW15_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428487}; Flags: Fragment;+++[E7EW68_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430279}; Flags: Fragment;+++[E7EWG2_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428404}; Flags: Fragment;+++[H0YC17_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430739}; Flags: Fragment;"]
[10319,"'LAMC3'",7,1,2,3.33333333333333,"05146///Amoebiasis+++04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05145///Toxoplasmosis+++05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04510///Focal adhesion",{"$nulls":3},"GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005604///basement membrane","GO:0005198///structural molecule activity","GO:0030198///extracellular matrix organization+++GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0060041///retina development in camera-type eye+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0014002///astrocyte development","laminin subunit gamma 3","[LAMC3_HUMAN|Reviewed]RecName: Full=Laminin subunit gamma-3; AltName: Full=Laminin-12 subunit gamma; AltName: Full=Laminin-14 subunit gamma; AltName: Full=Laminin-15 subunit gamma; Flags: Precursor;+++[H7BY04_HUMAN|Unreviewed]SubName: Full=Laminin subunit gamma-3 {ECO:0000313|Ensembl:ENSP00000347627}; Flags: Fragment;+++[Q8N2D6_HUMAN|Unreviewed]SubName: Full=cDNA PSEC0236 fis, clone HEMBA1007104, highly similar to Laminin gamma-3 chain {ECO:0000313|EMBL:BAC11679.1};"]
[1032,"'CDKN2D'",25,47,27,33,"04068///FoxO signaling pathway+++04110///Cell cycle",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0097129///cyclin D2-CDK4 complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding","GO:0009411///response to UV+++GO:0033280///response to vitamin D+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0007605///sensory perception of sound+++GO:0042326///negative regulation of phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0007050///cell cycle arrest+++GO:0032526///response to retinoic acid+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:0007049///cell cycle+++GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","cyclin dependent kinase inhibitor 2D","[CDN2D_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor D; AltName: Full=p19-INK4d;+++[A0A024R796_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2D (P19, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAW84123.1};"]
[10320,"'IKZF1'",45,18,27,30,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0031618///nuclear pericentric heterochromatin+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding","GO:0030098///lymphocyte differentiation+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0051291///protein heterooligomerization+++GO:0006325///chromatin organization+++GO:0030218///erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007498///mesoderm development","IKAROS family zinc finger 1","[IKZF1_HUMAN|Reviewed]RecName: Full=DNA-binding protein Ikaros; AltName: Full=Ikaros family zinc finger protein 1; AltName: Full=Lymphoid transcription factor LyF-1;+++[A0A087WU46_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000478368};+++[A0A0A0MRA0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000340080};+++[A0A0A0MST1_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000401507};+++[A0A2R8Y4D3_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000493696};+++[A0A2R8Y4T7_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000494055}; Flags: Fragment;+++[A0A2R8YFR0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000496655}; Flags: Fragment;+++[C9JTB0_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000388478};+++[Q3T907_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000409588}; SubName: Full=Zinc finger protein, subfamily 1A, 1 (Ikaros) {ECO:0000313|EMBL:CAJ29975.1}; Flags: Fragment;+++[Q9P1M1_HUMAN|Unreviewed]SubName: Full=PRO0758 {ECO:0000313|EMBL:AAF71030.1}; SubName: Full=Zinc finger protein, subfamily 1A, 1 (Ikaros), isoform CRA_c {ECO:0000313|EMBL:EAW60980.1};+++[R9R4D9_HUMAN|Unreviewed]SubName: Full=DNA-binding protein Ikaros {ECO:0000313|Ensembl:ENSP00000483016}; SubName: Full=IKAROS family zinc finger 1 isoform 14 {ECO:0000313|EMBL:AGI59420.1};"]
[10322,"'SMYD5'",481,497,554,510.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0032259///methylation+++GO:0008150///biological_process","SMYD family member 5","[SMYD5_HUMAN|Reviewed]RecName: Full=SET and MYND domain-containing protein 5; EC=2.1.1.-; AltName: Full=Protein NN8-4AG; AltName: Full=Retinoic acid-induced protein 15;+++[C9IYN9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000412587}; Flags: Fragment;+++[E2QRN5_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000258100};+++[F8WEJ9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000388195};"]
[10324,"'KLHL41'",9,4,11,8,null,"H00698///Nemaline myopathy",null,null,"GO:0016529///sarcoplasmic reticulum+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031143///pseudopodium+++GO:0001726///ruffle+++GO:0031430///M band+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0035914///skeletal muscle cell differentiation+++GO:2000291///regulation of myoblast proliferation+++GO:0048741///skeletal muscle fiber development+++GO:0006941///striated muscle contraction+++GO:0030239///myofibril assembly+++GO:0045214///sarcomere organization+++GO:0043687///post-translational protein modification+++GO:0031275///regulation of lateral pseudopodium assembly+++GO:0045661///regulation of myoblast differentiation+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0016567///protein ubiquitination","kelch like family member 41","[KLH41_HUMAN|Reviewed]RecName: Full=Kelch-like protein 41; AltName: Full=Kel-like protein 23; AltName: Full=Kelch repeat and BTB domain-containing protein 10; AltName: Full=Kelch-related protein 1; AltName: Full=Sarcosin;+++[Q3ZTS6_HUMAN|Unreviewed]SubName: Full=Sarcomeric muscle protein {ECO:0000313|EMBL:AAQ76811.1}; Flags: Fragment;"]
[10325,"'RRAGB'",289,405,305,333,"04140///Autophagy - animal+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0034448///EGO complex+++GO:1990131///Gtr1-Gtr2 GTPase complex+++GO:0005765///lysosomal membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0051020///GTPase binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0032561///guanyl ribonucleotide binding","GO:1904263///positive regulation of TORC1 signaling+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0007050///cell cycle arrest+++GO:0034198///cellular response to amino acid starvation+++GO:0009267///cellular response to starvation+++GO:0034613///cellular protein localization+++GO:0010506///regulation of autophagy+++GO:0032006///regulation of TOR signaling+++GO:1990253///cellular response to leucine starvation","Ras related GTP binding B","[RRAGB_HUMAN|Reviewed]RecName: Full=Ras-related GTP-binding protein B {ECO:0000305}; Short=Rag B {ECO:0000303|PubMed:11073942}; Short=RagB {ECO:0000303|PubMed:7499430};+++[Q5VZM0_HUMAN|Unreviewed]SubName: Full=Ras-related GTP-binding protein B {ECO:0000313|Ensembl:ENSP00000410630}; Flags: Fragment;"]
[10327,"'AKR1A1'",874,899,1011,928,"01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++00040///Pentose and glucuronate interconversions+++00561///Glycerolipid metabolism+++00930///Caprolactam degradation+++01130///Biosynthesis of antibiotics+++01220///Degradation of aromatic compounds+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis",null,"M00014///Glucuronate pathway (uronate pathway)","R01041///glycerol:NADP+ oxidoreductase   Glycerol + NADP+ <=> D-Glyceraldehyde + NADPH + H++++R05231///6-Hydroxyhexanoate:NADP+ oxidoreductase   6-Hydroxyhexanoic acid + NADP+ <=> Adipate semialdehyde + NADPH + H++++R00746///Ethanol:NADP+ oxidoreductase   Ethanol + NADP+ <=> Acetaldehyde + NADPH + H++++R01481///L-gulonate:NADP+ 6-oxidoreductase   L-Gulonate + NADP+ <=> D-Glucuronate + NADPH + H+","GO:0045202///synapse+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0009055///electron transfer activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0047939///L-glucuronate reductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0005515///protein binding+++GO:0016972///thiol oxidase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0016491///oxidoreductase activity","GO:0042840///D-glucuronate catabolic process+++GO:0022900///electron transport chain+++GO:0006081///cellular aldehyde metabolic process+++GO:0019853///L-ascorbic acid biosynthetic process+++GO:1901687///glutathione derivative biosynthetic process+++GO:0006006///glucose metabolic process+++GO:0055114///oxidation-reduction process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0046185///aldehyde catabolic process","aldo-keto reductase family 1 member A1","[AK1A1_HUMAN|Reviewed]RecName: Full=Alcohol dehydrogenase [NADP(+)]; EC=1.1.1.2; AltName: Full=Aldehyde reductase; AltName: Full=Aldo-keto reductase family 1 member A1;+++[Q5T621_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000398414}; Flags: Fragment;+++[Q9H2X5_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[Q9NY86_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[V9GYG2_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476713};+++[V9GYP9_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476978}; Flags: Fragment;+++[V9HWI0_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 6 {ECO:0000313|EMBL:ACF94472.1}; SubName: Full=Epididymis secretory sperm binding protein Li 165mP {ECO:0000313|EMBL:ACJ13642.1};"]
[10328,"'EMC8'",294,316,306,305.333333333333,"00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01100///Metabolic pathways+++05016///Huntington's disease+++04714///Thermogenesis+++04260///Cardiac muscle contraction+++05012///Parkinson's disease","H00920///Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis","M00154///Cytochrome c oxidase",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0072546///ER membrane protein complex","GO:0005515///protein binding",null,"ER membrane protein complex subunit 8","[EMC8_HUMAN|Reviewed]RecName: Full=ER membrane protein complex subunit 8; AltName: Full=Neighbor of COX4; AltName: Full=Protein FAM158B;+++[M0R1B0_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 8 {ECO:0000313|Ensembl:ENSP00000471751}; Flags: Fragment;+++[Q53Y03_HUMAN|Unreviewed]SubName: Full=COX4 neighbor, isoform CRA_a {ECO:0000313|EMBL:EAW95439.1}; SubName: Full=Neighbor of COX4 {ECO:0000313|EMBL:AAP35796.1}; SubName: Full=cDNA, FLJ94626, Homo sapiens neighbor of COX4 (NOC4), mRNA {ECO:0000313|EMBL:BAG36691.1};"]
[10329,"'RXYLT1'",228,183,199,203.333333333333,"00515///Mannose type O-glycan biosynthesis+++01100///Metabolic pathways","H00120///Muscular dystrophy-dystroglycanopathy type A",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane","GO:0016740///transferase activity+++GO:0120053///ribitol beta-1,4-xylosyltransferase activity","GO:0035269///protein O-linked mannosylation+++GO:0006486///protein glycosylation","ribitol xylosyltransferase 1","[RXLT1_HUMAN|Reviewed]RecName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000305}; EC=2.4.2.- {ECO:0000269|PubMed:27733679}; AltName: Full=Transmembrane protein 5 {ECO:0000305}; AltName: Full=UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase {ECO:0000303|PubMed:27733679};+++[F5GXF8_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440845};+++[G3V1K2_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440280}; SubName: Full=Transmembrane protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW97120.1};"]
[1033,"'CDKN3'",109,86,97,97.3333333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity","GO:0006470///protein dephosphorylation+++GO:0007050///cell cycle arrest+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0007049///cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle","cyclin dependent kinase inhibitor 3","[CDKN3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=CDK2-associated dual-specificity phosphatase; AltName: Full=Cyclin-dependent kinase interactor 1; AltName: Full=Cyclin-dependent kinase-interacting protein 2; AltName: Full=Kinase-associated phosphatase;+++[A0A087WW25_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000479875};+++[A0A087WWK3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[A0A0S2KP18_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 splice variant {ECO:0000313|EMBL:ALO50058.1};+++[F5H232_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000445572};+++[F8WD24_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000378944};+++[G3V1K6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000440404};+++[G3V2J7_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[H7C0S3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};"]
[10330,"'CNPY2'",2323,2876,2931,2710,{"$nulls":4},"GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:0010629///negative regulation of gene expression+++GO:0045716///positive regulation of low-density lipoprotein particle receptor biosynthetic process","canopy FGF signaling regulator 2","[CNPY2_HUMAN|Reviewed]RecName: Full=Protein canopy homolog 2; AltName: Full=MIR-interacting saposin-like protein; AltName: Full=Putative secreted protein Zsig9; AltName: Full=Transmembrane protein 4; Flags: Precursor;+++[F8VXJ7_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448809}; Flags: Fragment;+++[F8W1K5_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000446784}; Flags: Fragment;+++[H0YI18_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448333}; Flags: Fragment;+++[H0YIH9_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000449444}; Flags: Fragment;"]
[10331,"'B3GNT3'",0,1,0,0.333333333333333,"01100///Metabolic pathways+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,null,"R04659///UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase   UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide+++R05974///UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + nLc7Cer+++R04636///UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-(1->3)-[N-acetyl-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R 3-beta-N-acetyl-D-glucosaminyltransferase   UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R <=> UDP + N-Acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R+++R05975///UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + nLc5Cer+++R05901///UDP-N-acetyl-D-glucosamine + G00025 <=> UDP + G00209","GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0000139///Golgi membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0047223///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity","GO:0018146///keratan sulfate biosynthetic process+++GO:0016266///O-glycan processing+++GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3","[B3GN3_HUMAN|Reviewed]RecName: Full=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3; EC=2.4.1.149 {ECO:0000269|PubMed:11042166}; AltName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase; EC=2.4.1.146 {ECO:0000269|PubMed:11439191}; AltName: Full=Beta-1,3-galactosyltransferase 8; Short=Beta-1,3-GalTase 8; Short=Beta3Gal-T8; Short=Beta3GalT8; Short=b3Gal-T8; AltName: Full=Beta-3-Gx-T8; AltName: Full=Core 1 extending beta-1,3-N-acetylglucosaminyltransferase {ECO:0000303|PubMed:11439191}; AltName: Full=Core1-beta3GlcNAcT {ECO:0000303|PubMed:11439191}; AltName: Full=Transmembrane protein 3; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; AltName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3; Short=BGnT-3; Short=Beta-1,3-Gn-T3; Short=Beta-1,3-N-acetylglucosaminyltransferase 3; Short=Beta3Gn-T3; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8;+++[M0QX58_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;+++[M0R199_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063}; Flags: Fragment;"]
[10332,"'CLEC4M'",0,0,1,0.333333333333333,"05162///Measles+++05152///Tuberculosis+++04145///Phagosome+++04625///C-type lectin receptor signaling pathway",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0043657///host cell+++GO:0005737///cytoplasm","GO:0046790///virion binding+++GO:0046872///metal ion binding+++GO:0005537///mannose binding+++GO:0030369///ICAM-3 receptor activity+++GO:0048306///calcium-dependent protein binding+++GO:0038023///signaling receptor activity+++GO:0042605///peptide antigen binding+++GO:0030246///carbohydrate binding+++GO:0001618///virus receptor activity","GO:0019062///virion attachment to host cell+++GO:0035556///intracellular signal transduction+++GO:0046718///viral entry into host cell+++GO:0019079///viral genome replication+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0016032///viral process+++GO:0002250///adaptive immune response+++GO:0075733///intracellular transport of virus+++GO:0045087///innate immune response+++GO:0009988///cell-cell recognition+++GO:0002376///immune system process+++GO:0006897///endocytosis+++GO:0019882///antigen processing and presentation+++GO:0046968///peptide antigen transport+++GO:0007159///leukocyte cell-cell adhesion","C-type lectin domain family 4 member M","[CLC4M_HUMAN|Reviewed]RecName: Full=C-type lectin domain family 4 member M; AltName: Full=CD209 antigen-like protein 1; AltName: Full=DC-SIGN-related protein; Short=DC-SIGNR; AltName: Full=Dendritic cell-specific ICAM-3-grabbing non-integrin 2; Short=DC-SIGN2; AltName: Full=Liver/lymph node-specific ICAM-3-grabbing non-integrin; Short=L-SIGN; AltName: CD_antigen=CD299;+++[B4E2Z5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52840, highly similar to C-type lectin domain family 4 member M {ECO:0000313|EMBL:BAG65307.1};+++[D6W656_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 4, member M, isoform CRA_b {ECO:0000313|EMBL:EAW68987.1};+++[E7ENS9_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 4 member M {ECO:0000313|Ensembl:ENSP00000377680};+++[H7BXU4_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 4 member M {ECO:0000313|Ensembl:ENSP00000335228};+++[M0QYX2_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 4 member M {ECO:0000313|Ensembl:ENSP00000470137};+++[M0QZ42_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 4 member M {ECO:0000313|Ensembl:ENSP00000470286}; Flags: Fragment;+++[Q2TB20_HUMAN|Unreviewed]SubName: Full=CLEC4M protein {ECO:0000313|EMBL:AAI10615.1};"]
[10333,"'TLR6'",16.02,13.73,7,12.25,"04620///Toll-like receptor signaling pathway+++05152///Tuberculosis+++05142///Chagas disease (American trypanosomiasis)+++04145///Phagosome",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0035355///Toll-like receptor 2-Toll-like receptor 6 protein complex+++GO:0045121///membrane raft+++GO:0030670///phagocytic vesicle membrane+++GO:0005794///Golgi apparatus","GO:0035663///Toll-like receptor 2 binding+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0071723///lipopeptide binding+++GO:0038023///signaling receptor activity+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0038124///toll-like receptor TLR6:TLR2 signaling pathway+++GO:0002376///immune system process+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0032493///response to bacterial lipoprotein+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:0046209///nitric oxide metabolic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043032///positive regulation of macrophage activation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045410///positive regulation of interleukin-6 biosynthetic process+++GO:2000483///negative regulation of interleukin-8 secretion+++GO:0045087///innate immune response+++GO:0002224///toll-like receptor signaling pathway+++GO:0001775///cell activation+++GO:0042742///defense response to bacterium+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:1904646///cellular response to amyloid-beta+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0034150///toll-like receptor 6 signaling pathway+++GO:0006954///inflammatory response+++GO:0042496///detection of diacyl bacterial lipopeptide+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0010628///positive regulation of gene expression+++GO:0001774///microglial cell activation+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0050707///regulation of cytokine secretion+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:0050702///interleukin-1 beta secretion+++GO:0071726///cellular response to diacyl bacterial lipopeptide","toll like receptor 6","[TLR6_HUMAN|Reviewed]RecName: Full=Toll-like receptor 6; AltName: CD_antigen=CD286; Flags: Precursor;+++[B2R933_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH37_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH42_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH44_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH45_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6RFS7_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS91_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS92_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS93_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS96_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS97_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS98_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS99_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CSA0_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D6R979_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000423326}; Flags: Fragment;+++[D6RAV7_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000424718}; Flags: Fragment;"]
[10335,"'MRVI1'",105,82,50,79,"04270///Vascular smooth muscle contraction+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031095///platelet dense tubular network membrane","GO:0005515///protein binding",null,"murine retrovirus integration site 1 homolog","[MRVI1_HUMAN|Reviewed]RecName: Full=Protein MRVI1; AltName: Full=Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; AltName: Full=JAW1-related protein MRVI1;+++[E9PJ61_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000435658};+++[E9PNK7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000434741};+++[E9PRG4_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432325}; Flags: Fragment;+++[E9PRH0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432312};+++[H0YCL0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000431845}; Flags: Fragment;+++[H0YDM7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000433970}; Flags: Fragment;+++[H0YI08_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432067};"]
[10336,"'PCGF3'",706,772,620,699.333333333333,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0035102///PRC1 complex+++GO:0005634///nucleus+++GO:0031519///PcG protein complex+++GO:0000805///X chromosome+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding","GO:0060819///inactivation of X chromosome by genetic imprinting+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036353///histone H2A-K119 monoubiquitination","polycomb group ring finger 3","[PCGF3_HUMAN|Reviewed]RecName: Full=Polycomb group RING finger protein 3; AltName: Full=RING finger protein 3A;+++[A0A087WVH5_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000479441};+++[B3KQ06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32562 fis, clone SPLEN1000165, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG51868.1};+++[B3KWT8_HUMAN|Unreviewed]SubName: Full=Polycomb group ring finger 3, isoform CRA_b {ECO:0000313|EMBL:EAW82654.1}; SubName: Full=cDNA FLJ43813 fis, clone TESTI4001467, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG54250.1};+++[B4DTN5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54810, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG62047.1};+++[B5MEC4_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000383015};+++[C9J3G7_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000398493}; Flags: Fragment;+++[C9JGV3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000416279}; Flags: Fragment;+++[C9JYD0_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000401431}; Flags: Fragment;+++[F2Z3P3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000405840};"]
[10342,"'TFG'",3326,3288,3305,3306.33333333333,"05200///Pathways in cancer+++05216///Thyroid cancer","H00266///Hereditary spastic paraplegia (SPG)+++H00032///Thyroid cancer",null,null,"GO:0070971///endoplasmic reticulum exit site+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport","TRK-fused gene","[TFG_HUMAN|Reviewed]RecName: Full=Protein TFG; AltName: Full=TRK-fused gene protein;+++[C9JJP5_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000420797}; Flags: Fragment;+++[C9JTY3_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419559}; Flags: Fragment;+++[C9JUE0_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419504}; Flags: Fragment;+++[Q05BK6_HUMAN|Unreviewed]SubName: Full=TFG protein {ECO:0000313|EMBL:AAH41600.1};"]
[10343,"'PKDREJ'",3,3,1,2.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005262///calcium channel activity+++GO:0005509///calcium ion binding","GO:0006811///ion transport+++GO:0050982///detection of mechanical stimulus+++GO:0007340///acrosome reaction+++GO:0070588///calcium ion transmembrane transport","polycystin family receptor for egg jelly","[PKDRE_HUMAN|Reviewed]RecName: Full=Polycystic kidney disease and receptor for egg jelly-related protein; AltName: Full=PKD and REJ homolog; Flags: Precursor;"]
[10344,"'CCL26'",21,38,26,28.3333333333333,"04062///Chemokine signaling pathway+++04060///Cytokine-cytokine receptor interaction","H01361///Eosinophilic esophagitis+++H01360///Allergic rhinitis",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008009///chemokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity+++GO:0048020///CCR chemokine receptor binding+++GO:0005125///cytokine activity+++GO:0031728///CCR3 chemokine receptor binding","GO:0043547///positive regulation of GTPase activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0048245///eosinophil chemotaxis+++GO:0006955///immune response+++GO:0071347///cellular response to interleukin-1+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0006954///inflammatory response+++GO:0048247///lymphocyte chemotaxis+++GO:0007267///cell-cell signaling+++GO:0070098///chemokine-mediated signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0050921///positive regulation of chemotaxis+++GO:0006935///chemotaxis+++GO:0071346///cellular response to interferon-gamma+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0010818///T cell chemotaxis+++GO:0002548///monocyte chemotaxis","C-C motif chemokine ligand 26","[CCL26_HUMAN|Reviewed]RecName: Full=C-C motif chemokine 26; AltName: Full=CC chemokine IMAC; AltName: Full=Eotaxin-3; AltName: Full=Macrophage inflammatory protein 4-alpha; Short=MIP-4-alpha; AltName: Full=Small-inducible cytokine A26; AltName: Full=Thymic stroma chemokine-1; Short=TSC-1; Flags: Precursor;"]
[10345,"'TRDN'",4,5,12,7,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0030314///junctional membrane complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0030674///protein binding, bridging","GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0090158///endoplasmic reticulum membrane organization+++GO:0006936///muscle contraction+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0010649///regulation of cell communication by electrical coupling+++GO:1903779///regulation of cardiac conduction+++GO:0060047///heart contraction+++GO:0009617///response to bacterium+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0031122///cytoplasmic microtubule organization+++GO:1901846///positive regulation of cell communication by electrical coupling involved in cardiac conduction","triadin","[TRDN_HUMAN|Reviewed]RecName: Full=Triadin;+++[H0Y6P0_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000406768}; Flags: Fragment;+++[H7BY47_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000354307}; Flags: Fragment;+++[H9ME53_HUMAN|Unreviewed]SubName: Full=Cardiac triadin Trisk 32 isoform {ECO:0000313|EMBL:AEW10557.1}; SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000439281};+++[Q05C44_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH29393.1}; Flags: Fragment;+++[Q6PG49_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH57222.1}; Flags: Fragment;+++[Q8IVK2_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|EMBL:CAD33526.2};"]
[10346,"'TRIM22'",1514,2116,2385,2005,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0016740///transferase activity+++GO:0003714///transcription corepressor activity+++GO:0030674///protein binding, bridging+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0016032///viral process+++GO:0010508///positive regulation of autophagy+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0016567///protein ubiquitination+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0009615///response to virus+++GO:0032880///regulation of protein localization+++GO:0051607///defense response to virus+++GO:0070206///protein trimerization+++GO:0006955///immune response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity","tripartite motif containing 22","[TRI22_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM22; EC=2.3.2.27; AltName: Full=50 kDa-stimulated trans-acting factor; AltName: Full=RING finger protein 94; AltName: Full=RING-type E3 ubiquitin transferase TRIM22 {ECO:0000305}; AltName: Full=Staf-50; AltName: Full=Tripartite motif-containing protein 22;+++[B4DQS5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51049, highly similar to Tripartite motif-containing protein 22 {ECO:0000313|EMBL:BAG61037.1};+++[C9J060_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000400417}; Flags: Fragment;+++[C9JIU5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000396849}; Flags: Fragment;+++[C9JWC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000393250}; Flags: Fragment;+++[D3DQT0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_b {ECO:0000313|EMBL:EAW68770.1};+++[D3DQT1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_a {ECO:0000313|EMBL:EAW68768.1};+++[H7BZD3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000388994}; Flags: Fragment;+++[H7C262_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000404204}; Flags: Fragment;+++[H7C2K0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000406412}; Flags: Fragment;+++[H7C376_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000409991}; Flags: Fragment;+++[Q4A1P5_HUMAN|Unreviewed]SubName: Full=Tripartite binding motif 22 {ECO:0000313|EMBL:CAJ13842.1}; Flags: Fragment;"]
[10347,"'ABCA7'",1664,1190,1104,1319.33333333333,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0001891///phagocytic cup+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0090556///phosphatidylserine-translocating ATPase activity+++GO:0034188///apolipoprotein A-I receptor activity+++GO:0005515///protein binding+++GO:0005319///lipid transporter activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:1902430///negative regulation of amyloid-beta formation+++GO:0033700///phospholipid efflux+++GO:0033344///cholesterol efflux+++GO:0050766///positive regulation of phagocytosis+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0018149///peptide cross-linking+++GO:0055085///transmembrane transport+++GO:0010875///positive regulation of cholesterol efflux+++GO:1902995///positive regulation of phospholipid efflux+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034504///protein localization to nucleus+++GO:0006909///phagocytosis+++GO:0007613///memory+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901076///positive regulation of engulfment of apoptotic cell+++GO:0045332///phospholipid translocation+++GO:0006869///lipid transport","ATP binding cassette subfamily A member 7","[ABCA7_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 7; AltName: Full=ABCA-SSN; AltName: Full=Autoantigen SS-N; AltName: Full=Macrophage ABC transporter;+++[A0A087WUR5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000478857}; Flags: Fragment;+++[A0A087WX86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000480811}; Flags: Fragment;+++[A0A087WZX6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000482948}; Flags: Fragment;+++[B3KUJ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40025 fis, clone STOMA2008050, highly similar to Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 7 (ABCA7), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53455.1};+++[D6W5Y0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family A (ABC1), member 7, isoform CRA_e {ECO:0000313|EMBL:EAW69563.1};+++[E9PKG5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000433545}; Flags: Fragment;+++[E9PL63_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000431473}; Flags: Fragment;+++[H0YCN5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000432031}; Flags: Fragment;+++[H0YF58_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000437311}; Flags: Fragment;+++[L8EB07_HUMAN|Unreviewed]SubName: Full=Alternative protein ABCA7 {ECO:0000313|EMBL:CCQ43618.1};"]
[10349,"'ABCA10'",18,13,20,17,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005319///lipid transporter activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0006869///lipid transport+++GO:0055085///transmembrane transport","ATP binding cassette subfamily A member 10","[ABCAA_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 10;+++[E5RFN6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000428032};+++[E5RFP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000430341};+++[H0YBL8_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000429795}; Flags: Fragment;+++[K7EMH5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000466506}; Flags: Fragment;+++[K7ERP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000468351}; Flags: Fragment;"]
[10350,"'ABCA9'",8.99,8,9.06,8.68333333333334,"02010///ABC transporters",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005319///lipid transporter activity","GO:0055085///transmembrane transport+++GO:0006869///lipid transport","ATP binding cassette subfamily A member 9","[ABCA9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 9;+++[H0Y4U7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000394264};+++[K7EJJ0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000465191}; Flags: Fragment;"]
[10352,"'WARS2'",135,103,126,121.333333333333,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03664///L-Tryptophan -tRNA(Trp) ligase (AMP-forming)   ATP + L-Tryptophan + tRNA(Trp) <=> AMP + Diphosphate + L-Tryptophanyl-tRNA(Trp)","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000166///nucleotide binding+++GO:0004830///tryptophan-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding","GO:0006436///tryptophanyl-tRNA aminoacylation+++GO:0001570///vasculogenesis+++GO:0006412///translation+++GO:0070183///mitochondrial tryptophanyl-tRNA aminoacylation+++GO:0006418///tRNA aminoacylation for protein translation","tryptophanyl tRNA synthetase 2, mitochondrial","[SYWM_HUMAN|Reviewed]RecName: Full=Tryptophan--tRNA ligase, mitochondrial; EC=6.1.1.2; AltName: Full=(Mt)TrpRS; AltName: Full=Tryptophanyl-tRNA synthetase; Short=TrpRS; Flags: Precursor;+++[B7Z448_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51886, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH12434.1};+++[B7Z6G7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53098, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH13253.1};"]
[1036,"'CDO1'",614,404,606,541.333333333333,"00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00430///Taurine and hypotaurine metabolism",null,null,"R00893///L-Cysteine:oxygen oxidoreductase   L-Cysteine + Oxygen <=> 3-Sulfino-L-alanine","GO:0005829///cytosol","GO:0005506///iron ion binding+++GO:0017172///cysteine dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0008198///ferrous iron binding+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","GO:0010243///response to organonitrogen compound+++GO:0045471///response to ethanol+++GO:0051384///response to glucocorticoid+++GO:0019448///L-cysteine catabolic process+++GO:0043200///response to amino acid+++GO:0007595///lactation+++GO:0055114///oxidation-reduction process+++GO:0051591///response to cAMP+++GO:0000097///sulfur amino acid biosynthetic process+++GO:0006954///inflammatory response+++GO:0006534///cysteine metabolic process+++GO:0042412///taurine biosynthetic process+++GO:0033762///response to glucagon","cysteine dioxygenase type 1","[CDO1_HUMAN|Reviewed]RecName: Full=Cysteine dioxygenase type 1; EC=1.13.11.20; AltName: Full=Cysteine dioxygenase type I; Short=CDO; Short=CDO-I;"]
[10360,"'NPM3'",164,182,183,176.333333333333,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0038023///signaling receptor activity","GO:0009303///rRNA transcription+++GO:0070267///oncosis+++GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing","nucleophosmin/nucleoplasmin 3","[NPM3_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-3;"]
[10361,"'NPM2'",4,3,6,4.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0000789///cytoplasmic chromatin+++GO:0000790///nuclear chromatin+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0042393///histone binding","GO:0007338///single fertilization+++GO:0009994///oocyte differentiation+++GO:0006325///chromatin organization+++GO:0051260///protein homooligomerization+++GO:0045740///positive regulation of DNA replication+++GO:0043085///positive regulation of catalytic activity+++GO:0001824///blastocyst development+++GO:0006338///chromatin remodeling+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0051054///positive regulation of DNA metabolic process+++GO:0007275///multicellular organism development+++GO:0007096///regulation of exit from mitosis","nucleophosmin/nucleoplasmin 2","[NPM2_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-2;+++[E5RFQ8_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000428016}; Flags: Fragment;+++[E5RGN1_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000429984}; Flags: Fragment;"]
[10362,"'HMG20B'",1329,1451,1610,1463.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016604///nuclear body+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004407///histone deacetylase activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0035914///skeletal muscle cell differentiation+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007596///blood coagulation+++GO:0033234///negative regulation of protein sumoylation+++GO:0045666///positive regulation of neuron differentiation","high mobility group 20B","[HM20B_HUMAN|Reviewed]RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; Short=SMARCE1-related protein; AltName: Full=BRCA2-associated factor 35; AltName: Full=HMG box-containing protein 20B; AltName: Full=HMG domain-containing protein 2; AltName: Full=HMG domain-containing protein HMGX2; AltName: Full=Sox-like transcriptional factor; AltName: Full=Structural DNA-binding protein BRAF35;+++[A4IF61_HUMAN|Unreviewed]SubName: Full=HMG20B protein {ECO:0000313|EMBL:AAI34414.1}; Flags: Fragment;+++[B5MDG7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000262949}; Flags: Fragment;+++[C9J8X5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000410924}; Flags: Fragment;+++[C9JQA7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000402877}; Flags: Fragment;+++[C9K049_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393904}; Flags: Fragment;+++[F8WES5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393481};+++[K7EJR8_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000465293}; Flags: Fragment;+++[Q8WYT5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein pp8857 {ECO:0000313|EMBL:AAL55873.1};"]
[10363,"'HMG20A'",633,689,550,624,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:0033234///negative regulation of protein sumoylation+++GO:0045665///negative regulation of neuron differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006325///chromatin organization","high mobility group 20A","[HM20A_HUMAN|Reviewed]RecName: Full=High mobility group protein 20A; AltName: Full=HMG box-containing protein 20A; AltName: Full=HMG domain-containing protein 1; AltName: Full=HMG domain-containing protein HMGX1;+++[B4DMG1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57155, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAG59873.1}; SubName: Full=cDNA, FLJ79180, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAH14652.1};+++[H0YK55_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452665}; Flags: Fragment;+++[H0YKL0_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452847}; Flags: Fragment;+++[H0YKM5_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452864}; Flags: Fragment;+++[H0YM80_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453498}; Flags: Fragment;+++[H0YMG2_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453592};+++[H0YMS9_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453727}; Flags: Fragment;+++[H0YNS8_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000454136}; Flags: Fragment;"]
[10365,"'KLF2'",43,43,58,48,"05418///Fluid shear stress and atherosclerosis+++04371///Apelin signaling pathway+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0001701///in utero embryonic development+++GO:0070301///cellular response to hydrogen peroxide+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:0043249///erythrocyte maturation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060509///type I pneumocyte differentiation+++GO:0071498///cellular response to fluid shear stress+++GO:0035264///multicellular organism growth+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071409///cellular response to cycloheximide+++GO:0032715///negative regulation of interleukin-6 production+++GO:0000902///cell morphogenesis+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0034616///response to laminar fluid shear stress+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0040029///regulation of gene expression, epigenetic+++GO:1901653///cellular response to peptide+++GO:0071347///cellular response to interleukin-1+++GO:0051247///positive regulation of protein metabolic process+++GO:0034101///erythrocyte homeostasis+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0097533///cellular stress response to acid chemical+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0000122///negative regulation of transcription by RNA polymerase II","Kruppel like factor 2","[KLF2_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 2; AltName: Full=Lung krueppel-like factor;+++[K7EJ60_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 2 {ECO:0000313|Ensembl:ENSP00000465035};"]
[10367,"'MICU1'",1058,1099,1226,1127.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0032592///integral component of mitochondrial membrane+++GO:0034704///calcium channel complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005622///intracellular+++GO:1990246///uniplex complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0042802///identical protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0070509///calcium ion import+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051260///protein homooligomerization+++GO:0006952///defense response+++GO:0036444///calcium import into the mitochondrion+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0006851///mitochondrial calcium ion transmembrane transport","mitochondrial calcium uptake 1","[MICU1_HUMAN|Reviewed]RecName: Full=Calcium uptake protein 1, mitochondrial; AltName: Full=Atopy-related autoantigen CALC {ECO:0000303|PubMed:16002733}; Short=ara CALC {ECO:0000303|PubMed:16002733}; AltName: Full=Calcium-binding atopy-related autoantigen 1 {ECO:0000303|PubMed:16002733}; AltName: Allergen=Hom s 4 {ECO:0000303|PubMed:16002733}; Flags: Precursor;+++[A0A0U1RRK1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000489563};+++[A0A286YF11_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000493232};+++[E9PQV6_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000432492}; Flags: Fragment;+++[F6XEV2_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000381745};+++[S4R3D7_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474192}; Flags: Fragment;+++[S4R3V1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474775}; Flags: Fragment;+++[S4R3W3_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474809}; Flags: Fragment;"]
[10369,"'CACNG2'",0,3,0,1,"04260///Cardiac muscle contraction+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04921///Oxytocin signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04010///MAPK signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++05410///Hypertrophic cardiomyopathy (HCM)","H00773///Autosomal dominant mental retardation",null,null,"GO:0045202///synapse+++GO:0044300///cerebellar mossy fiber+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0032281///AMPA glutamate receptor complex+++GO:0016020///membrane+++GO:0030666///endocytic vesicle membrane+++GO:0098978///glutamatergic synapse+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0036477///somatodendritic compartment+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:0043005///neuron projection+++GO:0005891///voltage-gated calcium channel complex+++GO:0014069///postsynaptic density+++GO:0016021///integral component of membrane+++GO:0098839///postsynaptic density membrane","GO:0005244///voltage-gated ion channel activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0016247///channel regulator activity+++GO:0005515///protein binding+++GO:0005262///calcium channel activity+++GO:0005245///voltage-gated calcium channel activity","GO:2000969///positive regulation of AMPA receptor activity+++GO:0099590///neurotransmitter receptor internalization+++GO:0006816///calcium ion transport+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0034765///regulation of ion transmembrane transport+++GO:0051592///response to calcium ion+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:1904510///positive regulation of protein localization to basolateral plasma membrane+++GO:0007528///neuromuscular junction development+++GO:2000311///regulation of AMPA receptor activity+++GO:0050877///nervous system process+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0019226///transmission of nerve impulse+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0060081///membrane hyperpolarization+++GO:0006612///protein targeting to membrane+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0060082///eye blink reflex+++GO:0042391///regulation of membrane potential+++GO:0006811///ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0051899///membrane depolarization","calcium voltage-gated channel auxiliary subunit gamma 2","[CCG2_HUMAN|Reviewed]RecName: Full=Voltage-dependent calcium channel gamma-2 subunit; AltName: Full=Neuronal voltage-gated calcium channel gamma-2 subunit; AltName: Full=Transmembrane AMPAR regulatory protein gamma-2; Short=TARP gamma-2;"]
[10370,"'CITED2'",3624,3560,3564,3582.66666666667,"04137///Mitophagy - animal","H01926///Ventricular septal defect (VSD)+++H00546///Atrial septal defect",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin","GO:0046332///SMAD binding+++GO:0050693///LBD domain binding+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding+++GO:0035035///histone acetyltransferase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding","GO:0007417///central nervous system development+++GO:0070986///left/right axis specification+++GO:0060411///cardiac septum morphogenesis+++GO:0009612///response to mechanical stimulus+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0034405///response to fluid shear stress+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030851///granulocyte differentiation+++GO:0003197///endocardial cushion development+++GO:0007507///heart development+++GO:0008584///male gonad development+++GO:0061308///cardiac neural crest cell development involved in heart development+++GO:0043066///negative regulation of apoptotic process+++GO:2000020///positive regulation of male gonad development+++GO:0060349///bone morphogenesis+++GO:0021602///cranial nerve morphogenesis+++GO:0048821///erythrocyte development+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0048538///thymus development+++GO:0007530///sex determination+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0001947///heart looping+++GO:0045787///positive regulation of cell cycle+++GO:0035914///skeletal muscle cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0061371///determination of heart left/right asymmetry+++GO:0001944///vasculature development+++GO:0001889///liver development+++GO:0001701///in utero embryonic development+++GO:0007422///peripheral nervous system development+++GO:0001829///trophectodermal cell differentiation+++GO:0008283///cell proliferation+++GO:0001570///vasculogenesis+++GO:0001568///blood vessel development+++GO:0001841///neural tube formation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0030325///adrenal gland development+++GO:0003156///regulation of animal organ formation+++GO:0035802///adrenal cortex formation+++GO:0003151///outflow tract morphogenesis+++GO:0043627///response to estrogen+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:1900164///nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0071363///cellular response to growth factor stimulus+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0007275///multicellular organism development+++GO:0030336///negative regulation of cell migration+++GO:0007368///determination of left/right symmetry+++GO:0060412///ventricular septum morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001666///response to hypoxia+++GO:0048536///spleen development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002521///leukocyte differentiation+++GO:0001843///neural tube closure+++GO:0007569///cell aging+++GO:0001892///embryonic placenta development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0003281///ventricular septum development+++GO:0061156///pulmonary artery morphogenesis+++GO:0046697///decidualization+++GO:0060136///embryonic process involved in female pregnancy","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2","[CITE2_HUMAN|Reviewed]RecName: Full=Cbp/p300-interacting transactivator 2; AltName: Full=MSG-related protein 1; Short=MRG-1; AltName: Full=P35srj;+++[A0A0A0MTM3_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator 2 {ECO:0000313|Ensembl:ENSP00000444198};+++[D9ZGF1_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 {ECO:0000313|EMBL:ADL14510.1}; SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, isoform CRA_d {ECO:0000313|EMBL:EAW47894.1};"]
[10371,"'SEMA3A'",415,322,274,337,"04360///Axon guidance","H00556///CHARGE syndrome+++H00255///Hypogonadotropic hypogonadism","M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin","GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030424///axon+++GO:0005887///integral component of plasma membrane+++GO:0030425///dendrite","GO:0045499///chemorepellent activity+++GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding","GO:0002027///regulation of heart rate+++GO:0001764///neuron migration+++GO:0021637///trigeminal nerve structural organization+++GO:0050919///negative chemotaxis+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:0021675///nerve development+++GO:0006915///apoptotic process+++GO:0048846///axon extension involved in axon guidance+++GO:0007411///axon guidance+++GO:0048813///dendrite morphogenesis+++GO:0030517///negative regulation of axon extension+++GO:0021785///branchiomotor neuron axon guidance+++GO:0060385///axonogenesis involved in innervation+++GO:0007413///axonal fasciculation+++GO:0048841///regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:1903045///neural crest cell migration involved in sympathetic nervous system development+++GO:0061549///sympathetic ganglion development+++GO:0001755///neural crest cell migration+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:0061551///trigeminal ganglion development+++GO:0046330///positive regulation of JNK cascade+++GO:0021612///facial nerve structural organization+++GO:2001224///positive regulation of neuron migration+++GO:0021772///olfactory bulb development+++GO:0030335///positive regulation of cell migration+++GO:0097490///sympathetic neuron projection extension+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0150020///basal dendrite arborization+++GO:0010633///negative regulation of epithelial cell migration+++GO:0048880///sensory system development+++GO:0010977///negative regulation of neuron projection development+++GO:0008045///motor neuron axon guidance+++GO:0007275///multicellular organism development+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:2000020///positive regulation of male gonad development+++GO:0097491///sympathetic neuron projection guidance+++GO:1903375///facioacoustic ganglion development+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030154///cell differentiation+++GO:0036486///ventral trunk neural crest cell migration+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048485///sympathetic nervous system development","semaphorin 3A","[SEM3A_HUMAN|Reviewed]RecName: Full=Semaphorin-3A; AltName: Full=Semaphorin III; Short=Sema III; Flags: Precursor;+++[A0A0C4DG50_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000402093}; Flags: Fragment;+++[C9J9C4_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000391900}; Flags: Fragment;+++[C9JD25_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000404800}; Flags: Fragment;+++[Q75MQ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAS02028.1}; Flags: Fragment;+++[Q86UJ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAP22350.1}; Flags: Fragment;"]
[10376,"'TUBA1B'",10378.02,7275.98,8788.16,8814.05333333333,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection+++04530///Tight junction+++04210///Apoptosis","H00058///Amyotrophic lateral sclerosis (ALS)+++H00268///Lissencephaly (LIS)+++H00271///Polymicrogyria",null,null,"GO:0005874///microtubule+++GO:0045121///membrane raft+++GO:0015630///microtubule cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath","GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007017///microtubule-based process+++GO:0000278///mitotic cell cycle+++GO:0071353///cellular response to interleukin-4+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0000226///microtubule cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0051301///cell division","tubulin alpha 1b","[TBA1B_HUMAN|Reviewed]RecName: Full=Tubulin alpha-1B chain; AltName: Full=Alpha-tubulin ubiquitous; AltName: Full=Tubulin K-alpha-1; AltName: Full=Tubulin alpha-ubiquitous chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1B chain;+++[F8VRK0_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448648}; Flags: Fragment;+++[F8VU66_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448045};+++[F8VVB9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449325}; Flags: Fragment;+++[F8VWV9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449460}; Flags: Fragment;+++[F8VX09_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449748}; Flags: Fragment;"]
[10379,"'IRF9'",1511,1887,2120,1839.33333333333,"05164///Influenza A+++04630///Jak-STAT signaling pathway+++05160///Hepatitis C+++05162///Measles+++05165///Human papillomavirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05168///Herpes simplex infection+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++05203///Viral carcinogenesis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity","GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0007166///cell surface receptor signaling pathway+++GO:0060337///type I interferon signaling pathway","interferon regulatory factor 9","[IRF9_HUMAN|Reviewed]RecName: Full=Interferon regulatory factor 9; Short=IRF-9; AltName: Full=IFN-alpha-responsive transcription factor subunit; AltName: Full=ISGF3 p48 subunit; AltName: Full=Interferon-stimulated gene factor 3 gamma; Short=ISGF-3 gamma; AltName: Full=Transcriptional regulator ISGF3 subunit gamma;+++[H0YMB0_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453534};+++[H0YMB6_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453540}; Flags: Fragment;+++[H0YNM9_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454078};+++[H0YNP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454095}; Flags: Fragment;+++[H7BXP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000313529}; Flags: Fragment;"]
[10380,"'BPNT1'",251,251,256,252.666666666667,"01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++00920///Sulfur metabolism+++01130///Biosynthesis of antibiotics",null,null,"R00508///3'-phospho-5'-adenylyl sulfate 3'-phosphohydrolase   3'-Phosphoadenylyl sulfate + H2O <=> Adenylyl sulfate + Orthophosphate+++R00188///adenosine-3',5'-bisphosphate 3'-phosphohydrolase   Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate","GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005615///extracellular space","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008441///3'(2'),5'-bisphosphate nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0019864///IgG binding+++GO:0004190///aspartic-type endopeptidase activity+++GO:0046983///protein dimerization activity+++GO:0003779///actin binding","GO:0070233///negative regulation of T cell apoptotic process+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0010628///positive regulation of gene expression+++GO:0055085///transmembrane transport+++GO:0001895///retina homeostasis+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0007399///nervous system development+++GO:0016311///dephosphorylation+++GO:0006508///proteolysis+++GO:0046854///phosphatidylinositol phosphorylation","3'(2'), 5'-bisphosphate nucleotidase 1","[BPNT1_HUMAN|Reviewed]RecName: Full=3'(2'),5'-bisphosphate nucleotidase 1; EC=3.1.3.7; AltName: Full=Bisphosphate 3'-nucleotidase 1; AltName: Full=PAP-inositol 1,4-phosphatase; Short=PIP;+++[A6NF51_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000346862};+++[B7Z9J7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78861, highly similar to 3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|EMBL:BAH14333.1};+++[F8VRY7_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000448740}; Flags: Fragment;+++[F8VVW8_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000449883}; Flags: Fragment;+++[F8VZG4_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446850}; Flags: Fragment;+++[F8W1J0_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446953}; Flags: Fragment;+++[V9HWF9_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 20 {ECO:0000313|EMBL:ACJ13648.1}; SubName: Full=Testicular tissue protein Li 29 {ECO:0000313|EMBL:AEE60942.1};"]
[10381,"'TUBB3'",4925.55,6159.74,6825.98,5970.42333333333,"04540///Gap junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H01579///Congenital symmetric circumferential skin creases+++H01740///Macrothrombocytopenia+++H00679///Hypomyelinating leukodystrophy+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect+++H00271///Polymicrogyria+++H01881///Complex cortical dysplasia with other brain malformations",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030424///axon","GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007017///microtubule-based process+++GO:0007411///axon guidance+++GO:0000278///mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0030182///neuron differentiation+++GO:0007010///cytoskeleton organization","tubulin beta 3 class III","[TBB3_HUMAN|Reviewed]RecName: Full=Tubulin beta-3 chain; AltName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin beta-III;+++[G3V2A3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[G3V2N6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_d {ECO:0000313|EMBL:EAW66672.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450765};+++[G3V2R8_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_e {ECO:0000313|EMBL:EAW66673.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450822};+++[G3V3J6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_b {ECO:0000313|EMBL:EAW66670.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451276};+++[G3V3R4_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_c {ECO:0000313|EMBL:EAW66671.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451378};+++[G3V3W7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451465};+++[G3V4U2_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451985};+++[G3V542_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452166}; Flags: Fragment;+++[G3V5W4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452554};+++[Q3ZCR3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q53G92_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q9BV28_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;"]
[10382,"'TUBB4A'",9171,5631,7540,7447.33333333333,"05130///Pathogenic Escherichia coli infection+++04540///Gap junction+++04145///Phagosome","H00679///Hypomyelinating leukodystrophy+++H01740///Macrothrombocytopenia+++H01881///Complex cortical dysplasia with other brain malformations+++H01897///Oocyte maturation defect+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01579///Congenital symmetric circumferential skin creases+++H00271///Polymicrogyria",null,null,"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005929///cilium+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0033269///internode region of axon+++GO:0042995///cell projection+++GO:0005930///axoneme+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005509///calcium ion binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007010///cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0031115///negative regulation of microtubule polymerization","tubulin beta 4A class IVa","[TBB4A_HUMAN|Reviewed]RecName: Full=Tubulin beta-4A chain; AltName: Full=Tubulin 5 beta; AltName: Full=Tubulin beta-4 chain;+++[M0QX14_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000468843};+++[M0QY37_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469560};+++[M0QY85_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469660}; Flags: Fragment;+++[M0QYM7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469936}; Flags: Fragment;+++[M0QZL7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000470627}; Flags: Fragment;+++[M0R042_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R0M1_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471320};+++[M0R0X0_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471503};+++[M0R1I1_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R278_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472375}; Flags: Fragment;+++[M0R2D3_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472481}; Flags: Fragment;+++[M0R2T4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472795};"]
[10383,"'TUBB4B'",5994.58,4261.24,5333.1,5196.30666666667,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection","H01579///Congenital symmetric circumferential skin creases+++H00679///Hypomyelinating leukodystrophy+++H01881///Complex cortical dysplasia with other brain malformations+++H01740///Macrothrombocytopenia+++H00271///Polymicrogyria+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect",null,null,"GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:1903561///extracellular vesicle+++GO:0035578///azurophil granule lumen+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005576///extracellular region","GO:0005200///structural constituent of cytoskeleton+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0042288///MHC class I protein binding+++GO:0005525///GTP binding+++GO:0051082///unfolded protein binding+++GO:0000166///nucleotide binding","GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0043312///neutrophil degranulation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0000226///microtubule cytoskeleton organization","tubulin beta 4B class IVb","[TBB4B_HUMAN|Reviewed]RecName: Full=Tubulin beta-4B chain; AltName: Full=Tubulin beta-2 chain; AltName: Full=Tubulin beta-2C chain;+++[Q8IZ29_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q8N6N5_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q96HX0_HUMAN|Unreviewed]SubName: Full=TUBB2C protein {ECO:0000313|EMBL:AAH08006.1}; Flags: Fragment;"]
[10384,"'BTN3A3'",71,133.99,145.01,116.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding","GO:0050852///T cell receptor signaling pathway+++GO:0050776///regulation of immune response+++GO:0002376///immune system process+++GO:0006366///transcription by RNA polymerase II+++GO:0002250///adaptive immune response+++GO:0015031///protein transport+++GO:0002456///T cell mediated immunity+++GO:0001701///in utero embryonic development","butyrophilin subfamily 3 member A3","[BT3A3_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 3 member A3; Flags: Precursor;+++[A0A024R042_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 3, member A3, isoform CRA_b {ECO:0000313|EMBL:EAW55574.1};+++[A0A089GIA6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 secreted isoform {ECO:0000313|EMBL:AIP98384.1};+++[C9J3Q8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417234}; Flags: Fragment;+++[C9J877_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417717}; Flags: Fragment;+++[C9JNZ3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420339}; Flags: Fragment;+++[C9JQT8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420147}; Flags: Fragment;+++[C9JUV8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419445}; Flags: Fragment;+++[C9JVU4_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419312}; Flags: Fragment;+++[C9JZT5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419736}; Flags: Fragment;+++[D6RDG3_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;+++[H0Y9Y1_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;"]
[10385,"'BTN2A2'",301,278,263,280.666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0050776///regulation of immune response+++GO:0031324///negative regulation of cellular metabolic process+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0050710///negative regulation of cytokine secretion","butyrophilin subfamily 2 member A2","[BT2A2_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 2 member A2; Flags: Precursor;+++[A0A024R038_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 2, member A2, isoform CRA_a {ECO:0000313|EMBL:EAW55564.1};+++[C9IY66_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418857}; Flags: Fragment;+++[C9IZY2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418965}; Flags: Fragment;+++[C9J8J5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418176}; Flags: Fragment;+++[C9J8R3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417676}; Flags: Fragment;+++[C9JAJ6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417511}; Flags: Fragment;+++[C9JWH2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000419226}; Flags: Fragment;+++[F8WC65_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418657};+++[H7C4E8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417129}; Flags: Fragment;"]
[10388,"'SYCP2'",13,11,12,12,{"$nulls":4},"GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000800///lateral element+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0000795///synaptonemal complex+++GO:0005694///chromosome+++GO:0032991///protein-containing complex","GO:0033814///propanoyl-CoA C-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0005102///signaling receptor binding+++GO:0050632///propionyl-CoA C2-trimethyltridecanoyltransferase activity+++GO:0000062///fatty-acyl-CoA binding+++GO:0003824///catalytic activity+++GO:0008289///lipid binding+++GO:0046982///protein heterodimerization activity+++GO:0070538///oleic acid binding","GO:0006701///progesterone biosynthetic process+++GO:1901373///lipid hydroperoxide transport+++GO:0072659///protein localization to plasma membrane+++GO:0007049///cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0007140///male meiotic nuclear division+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0045940///positive regulation of steroid metabolic process+++GO:0007143///female meiotic nuclear division+++GO:0036109///alpha-linolenic acid metabolic process+++GO:0009566///fertilization+++GO:0006699///bile acid biosynthetic process+++GO:0032385///positive regulation of intracellular cholesterol transport+++GO:0006869///lipid transport+++GO:0007031///peroxisome organization+++GO:0015914///phospholipid transport+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0051301///cell division+++GO:0006694///steroid biosynthetic process+++GO:0009887///animal organ morphogenesis+++GO:0048808///male genitalia morphogenesis+++GO:0051321///meiotic cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0006625///protein targeting to peroxisome","synaptonemal complex protein 2","[SYCP2_HUMAN|Reviewed]RecName: Full=Synaptonemal complex protein 2; Short=SCP-2; AltName: Full=Synaptonemal complex lateral element protein; Short=hsSCP2;+++[A2A2M9_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000399300}; Flags: Fragment;+++[A2A340_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000404358}; Flags: Fragment;+++[A2A341_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000402456}; Flags: Fragment;+++[A6QL60_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAI46799.1}; Flags: Fragment;+++[H0YCB0_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000431279}; Flags: Fragment;+++[H0YD06_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000432645}; Flags: Fragment;+++[H0YEU8_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000436581}; Flags: Fragment;+++[H0YF61_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000437317}; Flags: Fragment;+++[L0R5C7_HUMAN|Unreviewed]SubName: Full=Alternative protein SCP2 {ECO:0000313|EMBL:CCO13809.1};+++[Q8IWA1_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAH40566.1}; Flags: Fragment;"]
[10389,"'SCML2'",15,8,13,12,{"$nulls":4},"GO:0005634///nucleus+++GO:0031519///PcG protein complex","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0009653///anatomical structure morphogenesis","Scm polycomb group protein like 2","[SCML2_HUMAN|Reviewed]RecName: Full=Sex comb on midleg-like protein 2;+++[H0Y6S1_HUMAN|Unreviewed]SubName: Full=Sex comb on midleg-like protein 2 {ECO:0000313|Ensembl:ENSP00000407315}; Flags: Fragment;"]
[1039,"'CDR2'",1278,981,882,1047,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","cerebellar degeneration related protein 2","[CDR2_HUMAN|Reviewed]RecName: Full=Cerebellar degeneration-related protein 2; AltName: Full=Major Yo paraneoplastic antigen; AltName: Full=Paraneoplastic cerebellar degeneration-associated antigen;+++[H3BN65_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000454706}; Flags: Fragment;+++[H3BQS4_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000455915};+++[H3BTR1_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457289}; Flags: Fragment;+++[H3BU23_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457432}; Flags: Fragment;+++[H3BUE0_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457596}; Flags: Fragment;"]
[10390,"'CEPT1'",143,137,120,133.333333333333,"01100///Metabolic pathways+++00564///Glycerophospholipid metabolism+++00440///Phosphonate and phosphinate metabolism+++00565///Ether lipid metabolism+++01110///Biosynthesis of secondary metabolites","H00481///Cone-rod dystrophy and cone dystrophy","M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE+++M00090///Phosphatidylcholine (PC) biosynthesis, choline => PC","R04321///CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase   CDP-choline + 1-Alkyl-2-acetyl-sn-glycerol <=> CMP + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine+++R04922///CMP-N-trimethyl-2-aminoethylphosphonate:1,2-diacylglycerol (N-trimethyl-2-aminoethylphosphonyl)transferase   CMP-N-trimethyl-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate+++R02057///CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine+++R07389///1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP+++R04920///CMP-2-aminoethylphosphonate:1,2-diacylglycerol (2-aminoethylphosphonyl)transferase   CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate+++R07384///O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine+++R01321///CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase   CDP-choline + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylcholine+++R06364///CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine","GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane","GO:0004142///diacylglycerol cholinephosphotransferase activity+++GO:0046872///metal ion binding+++GO:0004307///ethanolaminephosphotransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups","GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006657///CDP-choline pathway+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process","choline/ethanolamine phosphotransferase 1","[CEPT1_HUMAN|Reviewed]RecName: Full=Choline/ethanolaminephosphotransferase 1; Short=hCEPT1; EC=2.7.8.1; EC=2.7.8.2;+++[A0A024R0C0_HUMAN|Unreviewed]SubName: Full=Choline/ethanolamine phosphotransferase 1, isoform CRA_b {ECO:0000313|EMBL:EAW56472.1};+++[A0A0C4DGS9_HUMAN|Unreviewed]SubName: Full=Choline/ethanolaminephosphotransferase 1 {ECO:0000313|Ensembl:ENSP00000477632};"]
[10391,"'CORO2B'",951,586,691,742.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding","GO:0030036///actin cytoskeleton organization","coronin 2B","[COR2B_HUMAN|Reviewed]RecName: Full=Coronin-2B; AltName: Full=Coronin-like protein C; Short=Clipin-C; AltName: Full=Protein FC96;"]
[103910,"'MYL12B'",3722,4272,4777,4257,"04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++04611///Platelet activation",{"$nulls":3},"GO:0099738///cell cortex region+++GO:0045177///apical part of cell+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005903///brush border+++GO:0001725///stress fiber+++GO:0070062///extracellular exosome","GO:0032036///myosin heavy chain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0008360///regulation of cell shape","myosin light chain 12B","[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;"]
[10392,"'NOD1'",92,106,75,91,"04621///NOD-like receptor signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05133///Pertussis+++05131///Shigellosis","H01358///Atopic dermatitis",null,"R03749///(5-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxoproline-forming) (5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid+++R02743///gamma-L-glutamyl-L-cysteine gamma-glutamyl cyclotransferase (5-oxoproline-forming) gamma-L-Glutamyl-L-cysteine <=> 5-Oxoproline + L-Cysteine","GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0042834///peptidoglycan binding+++GO:0050700///CARD domain binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0042802///identical protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0000187///activation of MAPK activity+++GO:0002376///immune system process+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0009595///detection of biotic stimulus+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0016045///detection of bacterium+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0042981///regulation of apoptotic process+++GO:0007165///signal transduction+++GO:0042742///defense response to bacterium+++GO:1904417///positive regulation of xenophagy+++GO:0006915///apoptotic process+++GO:0071225///cellular response to muramyl dipeptide+++GO:0050830///defense response to Gram-positive bacterium+++GO:0007254///JNK cascade+++GO:0042228///interleukin-8 biosynthetic process+++GO:0006954///inflammatory response+++GO:0035556///intracellular signal transduction+++GO:0006952///defense response+++GO:0010942///positive regulation of cell death+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","nucleotide binding oligomerization domain containing 1","[NOD1_HUMAN|Reviewed]RecName: Full=Nucleotide-binding oligomerization domain-containing protein 1; AltName: Full=Caspase recruitment domain-containing protein 4;+++[A0A024RA73_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4 {ECO:0000313|EMBL:EAL24453.1}; SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW93949.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 1 {ECO:0000313|EMBL:ALQ33972.1};+++[A0A0S2Z4W5_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 2 {ECO:0000313|EMBL:ALQ33973.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 3 {ECO:0000313|EMBL:ALQ33974.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 4 {ECO:0000313|EMBL:ALQ33975.1};+++[A0A1B0GX71_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000399505}; Flags: Fragment;+++[C9J8X8_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410917}; Flags: Fragment;+++[G3XAL1_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_c {ECO:0000313|EMBL:EAW93948.1}; SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000416946};"]
[10393,"'ANAPC10'",60,57,64,60.3333333333333,"04114///Oocyte meiosis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04111///Cell cycle - yeast+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex","GO:0016887///ATPase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0005506///iron ion binding+++GO:0060698///endoribonuclease inhibitor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding","GO:0007049///cell cycle+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0051301///cell division+++GO:0016567///protein ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition","anaphase promoting complex subunit 10","[APC10_HUMAN|Reviewed]RecName: Full=Anaphase-promoting complex subunit 10; Short=APC10; AltName: Full=Cyclosome subunit 10;+++[A0A286YEY6_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000493135};+++[D6R9Q5_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423223}; Flags: Fragment;+++[D6RA92_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423043}; Flags: Fragment;+++[D6RB36_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000424463}; Flags: Fragment;+++[D6RD74_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000425459};+++[Q4W5I2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein APC10 {ECO:0000313|EMBL:AAY40941.1}; Flags: Fragment;"]
[10395,"'DLC1'",824,674,727,741.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0071682///endocytic vesicle lumen+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0070062///extracellular exosome+++GO:1904724///tertiary granule lumen+++GO:0005615///extracellular space+++GO:0072562///blood microparticle+++GO:0035580///specific granule lumen+++GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0030492///hemoglobin binding+++GO:0016209///antioxidant activity+++GO:0005515///protein binding","GO:0042742///defense response to bacterium+++GO:0002376///immune system process+++GO:0042542///response to hydrogen peroxide+++GO:0006952///defense response+++GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis+++GO:0006953///acute-phase response+++GO:0098869///cellular oxidant detoxification+++GO:0043312///neutrophil degranulation+++GO:2000296///negative regulation of hydrogen peroxide catabolic process+++GO:0002526///acute inflammatory response+++GO:0010033///response to organic substance+++GO:0010942///positive regulation of cell death+++GO:0051354///negative regulation of oxidoreductase activity","DLC1 Rho GTPase activating protein","[RHG07_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 7; AltName: Full=Deleted in liver cancer 1 protein; Short=DLC-1; AltName: Full=HP protein; AltName: Full=Rho-type GTPase-activating protein 7; AltName: Full=START domain-containing protein 12; Short=StARD12; AltName: Full=StAR-related lipid transfer protein 12;+++[A0A087WU08_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000478279};+++[A0A0J9YWS8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000488100}; Flags: Fragment;+++[A0A0U4DJF7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40940.1}; Flags: Fragment;+++[A0A0U4DKQ8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40945.1}; Flags: Fragment;+++[A0A0U4ERW6_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40957.1}; Flags: Fragment;+++[A0A0U4EXB4_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40958.1}; Flags: Fragment;+++[A0A2X0SYX6_HUMAN|Unreviewed]SubName: Full=DLC1 {ECO:0000313|EMBL:SPT35739.1}; Flags: Fragment;+++[A8K119_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76742, highly similar to Homo sapiens deleted in liver cancer 1 (DLC1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF82423.1};+++[E5RI70_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000429537}; Flags: Fragment;+++[H0Y300_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000350406};+++[H3BMJ7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000454413};+++[H3BS21_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000456503}; Flags: Fragment;+++[J3KRH2_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000461999}; Flags: Fragment;+++[J3KSV1_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000462662}; Flags: Fragment;+++[J3QLC9_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463491}; Flags: Fragment;+++[J3QQI8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463755};+++[J3QR68_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000464070}; Flags: Fragment;+++[Q14552_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:AAA52686.1}; Flags: Fragment;+++[Q45XF9_HUMAN|Unreviewed]SubName: Full=Deleted in liver cancer 1 variant 2 {ECO:0000313|EMBL:AAZ32941.1}; Flags: Fragment;+++[Q6NSB4_HUMAN|Unreviewed]SubName: Full=HP protein {ECO:0000313|EMBL:AAH70299.1};+++[R4GMP5_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000473289}; Flags: Fragment;"]
[10396,"'ATP8A1'",338,179,139,218.666666666667,null,"H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0035579///specific granule membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005802///trans-Golgi network+++GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0042584///chromaffin granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0005524///ATP binding+++GO:0019829///cation-transporting ATPase activity","GO:0030335///positive regulation of cell migration+++GO:0061092///positive regulation of phospholipid translocation+++GO:0034220///ion transmembrane transport+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport+++GO:0007612///learning+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0043312///neutrophil degranulation+++GO:0006869///lipid transport","ATPase phospholipid transporting 8A1","[AT8A1_HUMAN|Reviewed]RecName: Full=Phospholipid-transporting ATPase IA; EC=3.6.3.1; AltName: Full=ATPase class I type 8A member 1; AltName: Full=Chromaffin granule ATPase II; AltName: Full=P4-ATPase flippase complex alpha subunit ATP8A1;+++[H0Y8I6_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000421164}; Flags: Fragment;+++[H0YAA1_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426495}; Flags: Fragment;+++[H0YAF4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426935}; Flags: Fragment;+++[H0YAJ4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000427295}; Flags: Fragment;+++[Q4G1C1_HUMAN|Unreviewed]SubName: Full=ATP8A1 protein {ECO:0000313|EMBL:AAH20943.1}; SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426636};"]
[10397,"'NDRG1'",629,473,684,595.333333333333,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0005815///microtubule organizing center+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton","GO:0017137///Rab GTPase binding+++GO:0043015///gamma-tubulin binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0045576///mast cell activation+++GO:0007165///signal transduction+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0099173///postsynapse organization+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0071456///cellular response to hypoxia+++GO:0042981///regulation of apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010038///response to metal ion+++GO:0042127///regulation of cell proliferation","N-myc downstream regulated 1","[NDRG1_HUMAN|Reviewed]RecName: Full=Protein NDRG1; AltName: Full=Differentiation-related gene 1 protein; Short=DRG-1; AltName: Full=N-myc downstream-regulated gene 1 protein; AltName: Full=Nickel-specific induction protein Cap43; AltName: Full=Reducing agents and tunicamycin-responsive protein; Short=RTP; AltName: Full=Rit42;+++[A0A024R9I3_HUMAN|Unreviewed]SubName: Full=N-myc downstream regulated gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW92166.1};+++[B3KWB2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ42719 fis, clone BRAMY3010492, highly similar to Protein NDRG1 {ECO:0000313|EMBL:BAG54074.1};+++[E5RG99_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428802}; Flags: Fragment;+++[E5RGG6_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000430171}; Flags: Fragment;+++[E5RGM5_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429994}; Flags: Fragment;+++[E5RH82_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429840}; Flags: Fragment;+++[E5RI76_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429524}; Flags: Fragment;+++[E5RIM2_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429380};+++[E5RIR1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428384}; Flags: Fragment;+++[E5RIV1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428345}; Flags: Fragment;+++[E5RJ98_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429172};+++[E5RJY1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000431057};+++[E5RK17_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428991}; Flags: Fragment;+++[E7ESM1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429007};+++[Q8N959_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38330 fis, clone FCBBF3025280, highly similar to NDRG1 PROTEIN {ECO:0000313|EMBL:BAC04597.1};"]
[10398,"'MYL9'",31201,38447,37563,35737,"04670///Leukocyte transendothelial migration+++04270///Vascular smooth muscle contraction+++04530///Tight junction+++04921///Oxytocin signaling pathway+++04024///cAMP signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005829///cytosol+++GO:0001725///stress fiber+++GO:0030018///Z disc+++GO:0005859///muscle myosin complex","GO:0046872///metal ion binding+++GO:0008307///structural constituent of muscle+++GO:0032036///myosin heavy chain binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0070527///platelet aggregation","myosin light chain 9","[MYL9_HUMAN|Reviewed]RecName: Full=Myosin regulatory light polypeptide 9; AltName: Full=20 kDa myosin light chain; Short=LC20; AltName: Full=MLC-2C; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 9; AltName: Full=Myosin regulatory light chain MRLC1;+++[Q6IBG1_HUMAN|Unreviewed]SubName: Full=MYL9 protein {ECO:0000313|EMBL:CAG33124.1};"]
[10399,"'RACK1'",15290,15582,16627,15833,"05162///Measles",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005840///ribosome+++GO:1990630///IRE1-RACK1-PP2A complex+++GO:0001891///phagocytic cup+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0015935///small ribosomal subunit+++GO:0042995///cell projection+++GO:0005654///nucleoplasm+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0044297///cell body+++GO:0030496///midbody+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043204///perikaryon+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0045296///cadherin binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0003723///RNA binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0008200///ion channel inhibitor activity+++GO:0030292///protein tyrosine kinase inhibitor activity+++GO:0043022///ribosome binding+++GO:0042169///SH2 domain binding+++GO:0005080///protein kinase C binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0019899///enzyme binding+++GO:0030332///cyclin binding+++GO:0019903///protein phosphatase binding+++GO:0035591///signaling adaptor activity+++GO:0042803///protein homodimerization activity","GO:0072344///rescue of stalled ribosome+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0032464///positive regulation of protein homooligomerization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006412///translation+++GO:0071363///cellular response to growth factor stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:1900102///negative regulation of endoplasmic reticulum unfolded protein response+++GO:0017148///negative regulation of translation+++GO:0032880///regulation of protein localization+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0043065///positive regulation of apoptotic process+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0007369///gastrulation+++GO:0040008///regulation of growth+++GO:0016567///protein ubiquitination+++GO:0030308///negative regulation of cell growth+++GO:0050765///negative regulation of phagocytosis+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0048511///rhythmic process+++GO:0043547///positive regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0006915///apoptotic process+++GO:2000304///positive regulation of ceramide biosynthetic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010629///negative regulation of gene expression+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:0006417///regulation of translation+++GO:2000543///positive regulation of gastrulation+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051726///regulation of cell cycle+++GO:0051302///regulation of cell division+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0043473///pigmentation+++GO:0071333///cellular response to glucose stimulus","receptor for activated C kinase 1","[RACK1_HUMAN|Reviewed]RecName: Full=Receptor of activated protein C kinase 1; AltName: Full=Cell proliferation-inducing gene 21 protein; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1; AltName: Full=Guanine nucleotide-binding protein subunit beta-like protein 12.3; AltName: Full=Human lung cancer oncogene 7 protein; Short=HLC-7; AltName: Full=Receptor for activated C kinase; AltName: Full=Small ribosomal subunit protein RACK1 {ECO:0000303|PubMed:24524803}; Contains: RecName: Full=Receptor of activated protein C kinase 1, N-terminally processed; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed;+++[D6R909_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422198};+++[D6R9L0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000423569}; Flags: Fragment;+++[D6R9Z1_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422029}; Flags: Fragment;+++[D6RAC2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422768};+++[D6RAU2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424760};+++[D6RBD0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424237}; Flags: Fragment;+++[D6RDI0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000420936};+++[D6REE5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000425008}; Flags: Fragment;+++[D6RF23_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426708};+++[D6RFX4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421416}; Flags: Fragment;+++[D6RFZ9_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421356}; Flags: Fragment;+++[D6RGK8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426270};+++[D6RHH4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426101};+++[D6RHJ5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426046};+++[E9KL35_HUMAN|Unreviewed]SubName: Full=Epididymis tissue sperm binding protein Li 3a {ECO:0000313|EMBL:ADU87634.1};+++[E9PD14_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426111};+++[H0Y8R5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421838}; Flags: Fragment;+++[H0Y8W2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422316}; Flags: Fragment;+++[H0Y9P0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424654}; Flags: Fragment;+++[H0YAF8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426960}; Flags: Fragment;+++[H0YAM7_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000427677}; Flags: Fragment;+++[I3QNU9_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein beta polypeptide 2-like 1 {ECO:0000313|EMBL:AFK13122.1}; Flags: Fragment;+++[J3KPE3_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000366013};"]
[104,"'ADARB1'",332,308,271,303.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm","GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003729///mRNA binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0004000///adenosine deaminase activity","GO:0006382///adenosine to inosine editing+++GO:0051726///regulation of cell cycle+++GO:0051607///defense response to virus+++GO:0021610///facial nerve morphogenesis+++GO:0061744///motor behavior+++GO:0050884///neuromuscular process controlling posture+++GO:0030336///negative regulation of cell migration+++GO:0007274///neuromuscular synaptic transmission+++GO:0008285///negative regulation of cell proliferation+++GO:0006396///RNA processing+++GO:0035264///multicellular organism growth+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0097049///motor neuron apoptotic process+++GO:0060384///innervation+++GO:0006397///mRNA processing+++GO:0021618///hypoglossal nerve morphogenesis+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060415///muscle tissue morphogenesis+++GO:0021965///spinal cord ventral commissure morphogenesis+++GO:0045087///innate immune response+++GO:0016553///base conversion or substitution editing","adenosine deaminase, RNA specific B1","[RED1_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific editase 1; EC=3.5.4.37; AltName: Full=RNA-editing deaminase 1; AltName: Full=RNA-editing enzyme 1; AltName: Full=dsRNA adenosine deaminase;+++[A0A0A0MSG8_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000387480}; Flags: Fragment;+++[Q86XN4_HUMAN|Unreviewed]SubName: Full=RNA adenosine deaminase {ECO:0000313|EMBL:AAB18134.1};+++[Q8TCX7_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000478160}; SubName: Full=HCG2008433 {ECO:0000313|EMBL:EAX09362.1};"]
[1040,"'CDS1'",136,105,102,114.333333333333,"04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,"M00093///Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE","R01799///CTP:phosphatidate cytidyltransferase   CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol","GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0004142///diacylglycerol cholinephosphotransferase activity","GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0007602///phototransduction+++GO:0007165///signal transduction+++GO:0006661///phosphatidylinositol biosynthetic process","CDP-diacylglycerol synthase 1","[CDS1_HUMAN|Reviewed]RecName: Full=Phosphatidate cytidylyltransferase 1; EC=2.7.7.41; AltName: Full=CDP-DAG synthase 1; AltName: Full=CDP-DG synthase 1; AltName: Full=CDP-diacylglycerol synthase 1; Short=CDS 1; AltName: Full=CDP-diglyceride pyrophosphorylase 1; AltName: Full=CDP-diglyceride synthase 1; AltName: Full=CTP:phosphatidate cytidylyltransferase 1;+++[A0A024RDG8_HUMAN|Unreviewed]RecName: Full=Phosphatidate cytidylyltransferase {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938}; EC=2.7.7.41 {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938};"]
[10400,"'PEMT'",470,554,628,550.666666666667,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites",null,"M00091///Phosphatidylcholine (PC) biosynthesis, PE => PC","R03424///S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine+++R02056///S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine+++R01320///S-adenosyl-L-methionine:phosphatidyl-N-dimethylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidylcholine","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0004603///phenylethanolamine N-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0042423///catecholamine biosynthetic process+++GO:0032259///methylation+++GO:0042418///epinephrine biosynthetic process","phosphatidylethanolamine N-methyltransferase","[PEMT_HUMAN|Reviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000255|HAMAP-Rule:MF_03216}; AltName: Full=PEMT2; AltName: Full=Phospholipid methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000255|HAMAP-Rule:MF_03216};+++[D3YTC7_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};+++[J3KTR2_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463112};+++[J3QLU8_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463713};+++[J3QRI3_HUMAN|Unreviewed]SubName: Full=Phenylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000464234};+++[Q6FHD9_HUMAN|Unreviewed]SubName: Full=PNMT protein {ECO:0000313|EMBL:CAG46614.1};+++[Q71UY0_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};"]
[10401,"'PIAS3'",1755,1376,1274,1468.33333333333,"04120///Ubiquitin mediated proteolysis+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0030425///dendrite+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0045202///synapse+++GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0015459///potassium channel regulator activity+++GO:0051059///NF-kappaB binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0019789///SUMO transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0047485///protein N-terminus binding","GO:0009725///response to hormone+++GO:0071847///TNFSF11-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010629///negative regulation of gene expression+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0033234///negative regulation of protein sumoylation+++GO:0033235///positive regulation of protein sumoylation+++GO:0045838///positive regulation of membrane potential+++GO:0016925///protein sumoylation","protein inhibitor of activated STAT 3","[PIAS3_HUMAN|Reviewed]RecName: Full=E3 SUMO-protein ligase PIAS3; EC=2.3.2.-; AltName: Full=E3 SUMO-protein transferase PIAS3 {ECO:0000305}; AltName: Full=Protein inhibitor of activated STAT protein 3;+++[B3KNI3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14651 fis, clone NT2RP2002193, highly similar to Protein inhibitor of activated STAT protein 3 {ECO:0000313|EMBL:BAG51345.1};+++[E7ESB4_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000376766}; Flags: Fragment;+++[E9PHH8_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000358304};+++[Q6IAR4_HUMAN|Unreviewed]SubName: Full=PIAS3 protein {ECO:0000313|EMBL:CAG33371.1}; SubName: Full=Protein inhibitor of activated STAT3 {ECO:0000313|EMBL:AAP35684.1};+++[U3KQV1_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000476245}; Flags: Fragment;"]
[10402,"'ST3GAL6'",16,13,11,13.3333333333333,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++01100///Metabolic pathways",null,null,"R06026///CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-3-paragloboside+++R06037///CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI3NeuAc-nLc6Cer","GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0052798///beta-galactoside alpha-2,3-sialyltransferase activity","GO:0006464///cellular protein modification process+++GO:0006486///protein glycosylation+++GO:0071354///cellular response to interleukin-6+++GO:0009311///oligosaccharide metabolic process+++GO:0006664///glycolipid metabolic process+++GO:0009247///glycolipid biosynthetic process+++GO:0097503///sialylation+++GO:0018146///keratan sulfate biosynthetic process","ST3 beta-galactoside alpha-2,3-sialyltransferase 6","[SIA10_HUMAN|Reviewed]RecName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase; EC=2.4.99.-; AltName: Full=CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; AltName: Full=ST3Gal VI; Short=ST3GalVI; AltName: Full=Sialyltransferase 10;+++[A0A087WXB8_HUMAN|Unreviewed]SubName: Full=ST3 beta-galactoside alpha-2,3-sialyltransferase 6, isoform CRA_b {ECO:0000313|EMBL:EAW79851.1}; SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000480884};+++[C9IZL6_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418650}; Flags: Fragment;+++[C9J0E2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418896}; Flags: Fragment;+++[C9J480_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417201}; Flags: Fragment;+++[C9J9Y4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417584}; Flags: Fragment;+++[C9JMW7_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000420474};+++[C9JWI9_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419209}; Flags: Fragment;+++[C9JWJ3_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419202}; Flags: Fragment;+++[C9JXM2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419987}; Flags: Fragment;+++[F2Z2F4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417109};+++[F8WC98_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418581};"]
[10403,"'NDC80'",9,12,14,11.6666666666667,{"$nulls":4},"GO:0005694///chromosome+++GO:0031262///Ndc80 complex+++GO:0005829///cytosol+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005813///centrosome+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000777///condensed chromosome kinetochore","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0051383///kinetochore organization+++GO:1905342///positive regulation of protein localization to kinetochore+++GO:0000070///mitotic sister chromatid segregation+++GO:0000278///mitotic cell cycle+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0007059///chromosome segregation+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0051301///cell division+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0000132///establishment of mitotic spindle orientation","NDC80, kinetochore complex component","[NDC80_HUMAN|Reviewed]RecName: Full=Kinetochore protein NDC80 homolog; AltName: Full=Highly expressed in cancer protein; AltName: Full=Kinetochore protein Hec1; Short=HsHec1; AltName: Full=Kinetochore-associated protein 2; AltName: Full=Retinoblastoma-associated protein HEC;+++[A8K031_HUMAN|Unreviewed]SubName: Full=Kinetochore associated 2, isoform CRA_a {ECO:0000313|EMBL:EAX01696.1}; SubName: Full=NDC80 homolog, kinetochore complex component (S. cerevisiae) {ECO:0000313|EMBL:AAH35617.1}; SubName: Full=cDNA FLJ77925, highly similar to Homo sapiens kinetochore associated 2, mRNA {ECO:0000313|EMBL:BAF82085.1}; SubName: Full=cDNA, FLJ93683, Homo sapiens kinetochore associated 2 (KNTC2), mRNA {ECO:0000313|EMBL:BAG36001.1};+++[I3L0P0_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000458236}; Flags: Fragment;+++[I3L4G3_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000461227}; Flags: Fragment;+++[Q05DQ6_HUMAN|Unreviewed]SubName: Full=NDC80 protein {ECO:0000313|EMBL:AAH05239.1}; Flags: Fragment;+++[V9GYM9_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000476919}; Flags: Fragment;"]
[10404,"'CPQ'",512,417,448,459,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0042803///protein homodimerization activity+++GO:0008233///peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0070573///metallodipeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding","GO:0042246///tissue regeneration+++GO:0043171///peptide catabolic process+++GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation","carboxypeptidase Q","[CBPQ_HUMAN|Reviewed]RecName: Full=Carboxypeptidase Q; EC=3.4.17.-; AltName: Full=Lysosomal dipeptidase; AltName: Full=Plasma glutamate carboxypeptidase; Flags: Precursor;+++[A0A024R9B8_HUMAN|Unreviewed]SubName: Full=Plasma glutamate carboxypeptidase, isoform CRA_a {ECO:0000313|EMBL:EAW91758.1};+++[E5RH35_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429934}; Flags: Fragment;+++[E5RJA8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429146}; Flags: Fragment;+++[E5RJP8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431114}; Flags: Fragment;+++[E5RJZ7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431024}; Flags: Fragment;+++[H0YBB7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429134}; Flags: Fragment;"]
[10406,"'WFDC2'",104,54,74,77.3333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0010466///negative regulation of peptidase activity","WAP four-disulfide core domain 2","[WFDC2_HUMAN|Reviewed]RecName: Full=WAP four-disulfide core domain protein 2; AltName: Full=Epididymal secretory protein E4; AltName: Full=Major epididymis-specific protein E4; AltName: Full=Putative protease inhibitor WAP5; Flags: Precursor;+++[A8K2M3_HUMAN|Unreviewed]SubName: Full=WAP four-disulfide core domain 2, isoform CRA_c {ECO:0000313|EMBL:EAW75838.1}; SubName: Full=WAP four-disulfide core domain protein 2 {ECO:0000313|Ensembl:ENSP00000404760}; SubName: Full=cDNA FLJ76533, highly similar to Homo sapiens WAP four-disulfide core domain 2 (WFDC2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF82977.1};"]
[10408,"'MYCNOS'",0,0,1,0.333333333333333,"05202///Transcriptional misregulation in cancer","H00510///Feingold syndrome+++H00043///Neuroblastoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0031647///regulation of protein stability+++GO:0033673///negative regulation of kinase activity+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation","MYCN opposite strand","[NCYM_HUMAN|Reviewed]RecName: Full=N-cym protein; AltName: Full=N-myc opposite strand;"]
[10409,"'BASP1'",3003,3945,3693,3547,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0030426///growth cone+++GO:0031982///vesicle+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome","GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding","GO:0060421///positive regulation of heart growth+++GO:0060539///diaphragm development+++GO:0021762///substantia nigra development+++GO:0072075///metanephric mesenchyme development+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:2001076///positive regulation of metanephric ureteric bud development+++GO:0007356///thorax and anterior abdomen determination+++GO:0060231///mesenchymal to epithelial transition+++GO:0008406///gonad development+++GO:0045892///negative regulation of transcription, DNA-templated","brain abundant membrane attached signal protein 1","[BASP1_HUMAN|Reviewed]RecName: Full=Brain acid soluble protein 1; AltName: Full=22 kDa neuronal tissue-enriched acidic protein; AltName: Full=Neuronal axonal membrane protein NAP-22;+++[U3KQP0_HUMAN|Unreviewed]SubName: Full=Brain acid soluble protein 1 {ECO:0000313|Ensembl:ENSP00000476090}; Flags: Fragment;"]
[1041,"'CDSN'",12,11,12,11.6666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0001533///cornified envelope+++GO:0030057///desmosome+++GO:0005911///cell-cell junction","GO:0042803///protein homodimerization activity","GO:0008544///epidermis development+++GO:0070268///cornification+++GO:0030216///keratinocyte differentiation+++GO:0003336///corneocyte desquamation+++GO:0007155///cell adhesion+++GO:1905716///negative regulation of cornification+++GO:0043589///skin morphogenesis+++GO:0098609///cell-cell adhesion","corneodesmosin","[CDSN_HUMAN|Reviewed]RecName: Full=Corneodesmosin; AltName: Full=S protein; Flags: Precursor;+++[D2IYL2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77254.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:ACZ95707.1};+++[G8JLG2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77255.1}; SubName: Full=Corneodesmosin {ECO:0000313|Ensembl:ENSP00000365465};+++[M1SWB8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77250.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AGG40963.1};+++[Q0EFA5_HUMAN|Unreviewed]SubName: Full=S protein {ECO:0000313|EMBL:BAF31283.1};+++[Q2L6G8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77252.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:BAE78625.1, ECO:0000313|Ensembl:ENSP00000373023};+++[Q7Z559_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94641.1}; Flags: Fragment;+++[Q7Z560_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94640.1}; Flags: Fragment;"]
[10410,"'IFITM3'",22184.05,27298.43,41735.7,30406.06,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0032991///protein-containing complex+++GO:0005768///endosome+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0060337///type I interferon signaling pathway+++GO:0032897///negative regulation of viral transcription+++GO:0002376///immune system process+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0046597///negative regulation of viral entry into host cell+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0006955///immune response+++GO:0009615///response to virus+++GO:0051607///defense response to virus","interferon induced transmembrane protein 3","[IFM3_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 3; AltName: Full=Dispanin subfamily A member 2b; Short=DSPA2b; AltName: Full=Interferon-inducible protein 1-8U;+++[E9PS44_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000432108};+++[H9NKY4_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60318.1};+++[H9NL12_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60346.1};+++[H9NL19_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60353.1};+++[R4GNG9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000473645}; Flags: Fragment;"]
[10411,"'RAPGEF3'",39,49,40,42.6666666666667,"04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04720///Long-term potentiation+++04726///Serotonergic synapse+++04670///Leukocyte transendothelial migration+++04261///Adrenergic signaling in cardiomyocytes+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005902///microvillus+++GO:0030864///cortical actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0030175///filopodium","GO:0005515///protein binding+++GO:0030552///cAMP binding+++GO:0000166///nucleotide binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019904///protein domain specific binding+++GO:0017034///Rap guanyl-nucleotide exchange factor activity","GO:0019933///cAMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0051496///positive regulation of stress fiber assembly+++GO:0007264///small GTPase mediated signal transduction+++GO:0034242///negative regulation of syncytium formation by plasma membrane fusion+++GO:1901985///positive regulation of protein acetylation+++GO:0071320///cellular response to cAMP+++GO:0050796///regulation of insulin secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:0032486///Rap protein signal transduction+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:0061028///establishment of endothelial barrier+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0046827///positive regulation of protein export from nucleus+++GO:0043547///positive regulation of GTPase activity+++GO:0060143///positive regulation of syncytium formation by plasma membrane fusion","Rap guanine nucleotide exchange factor 3","[RPGF3_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 3; AltName: Full=Exchange factor directly activated by cAMP 1; AltName: Full=Exchange protein directly activated by cAMP 1; Short=EPAC 1; AltName: Full=Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; AltName: Full=cAMP-regulated guanine nucleotide exchange factor I; Short=cAMP-GEFI;+++[F8VRX1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448480};+++[F8VVJ6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449905};+++[F8VXK1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448804}; Flags: Fragment;+++[F8W0N0_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000446731}; Flags: Fragment;+++[H0YHS2_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000447691}; Flags: Fragment;+++[H0YIP6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449818}; Flags: Fragment;+++[Q569L6_HUMAN|Unreviewed]SubName: Full=RAPGEF3 protein {ECO:0000313|EMBL:AAH92404.2};+++[Q99777_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAB50216.1}; Flags: Fragment;"]
[10412,"'NSA2'",1038,1025,1060,1041,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing","NSA2, ribosome biogenesis homolog","[NSA2_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein NSA2 homolog; AltName: Full=Hairy cell leukemia protein 1; AltName: Full=TGF-beta-inducible nuclear protein 1;+++[A0A0A0MQZ6_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000296802};+++[H0YAI9_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000427266}; Flags: Fragment;+++[Q5J7U2_HUMAN|Unreviewed]SubName: Full=TGF beta-inducible nuclear protein 1 {ECO:0000313|EMBL:EAW95749.1}; SubName: Full=TGF-beta inducible nuclear protein {ECO:0000313|EMBL:AAS00024.1}; SubName: Full=cDNA, FLJ94393, Homo sapiens TGF beta-inducible nuclear protein 1 (TINP1), mRNA {ECO:0000313|EMBL:BAG36522.1};"]
[10413,"'YAP1'",2184,2163,1623,1990,"04391///Hippo signaling pathway - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species",null,"M00683///Hippo signaling",null,"GO:0005737///cytoplasm+++GO:0071148///TEAD-1-YAP complex+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071149///TEAD-2-YAP complex","GO:0046982///protein heterodimerization activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0070064///proline-rich region binding+++GO:0033613///activating transcription factor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0008022///protein C-terminus binding+++GO:0003714///transcription corepressor activity","GO:0010468///regulation of gene expression+++GO:0035019///somatic stem cell population maintenance+++GO:0048368///lateral mesoderm development+++GO:0030903///notochord development+++GO:0042127///regulation of cell proliferation+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0001570///vasculogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0048339///paraxial mesoderm development+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0035329///hippo signaling+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000737///negative regulation of stem cell differentiation+++GO:0060242///contact inhibition+++GO:0010837///regulation of keratinocyte proliferation+++GO:0060449///bud elongation involved in lung branching+++GO:0072091///regulation of stem cell proliferation+++GO:0032570///response to progesterone+++GO:0060487///lung epithelial cell differentiation+++GO:0008283///cell proliferation+++GO:0061026///cardiac muscle tissue regeneration+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:1902459///positive regulation of stem cell population maintenance+++GO:0046622///positive regulation of organ growth+++GO:0050767///regulation of neurogenesis+++GO:0003015///heart process+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0003143///embryonic heart tube morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001894///tissue homeostasis+++GO:0008284///positive regulation of cell proliferation+++GO:0071300///cellular response to retinoic acid+++GO:0030216///keratinocyte differentiation+++GO:0050847///progesterone receptor signaling pathway+++GO:0071480///cellular response to gamma radiation+++GO:0065003///protein-containing complex assembly","Yes associated protein 1","[YAP1_HUMAN|Reviewed]RecName: Full=Transcriptional coactivator YAP1; Short=Yes-associated protein 1; AltName: Full=Protein yorkie homolog; AltName: Full=Yes-associated protein YAP65 homolog;+++[A0A024R3E4_HUMAN|Unreviewed]SubName: Full=Yes-associated protein 1, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW67014.1};+++[H0YCI3_HUMAN|Unreviewed]SubName: Full=Transcriptional coactivator YAP1 {ECO:0000313|Ensembl:ENSP00000431626}; Flags: Fragment;+++[K0KVU2_HUMAN|Unreviewed]SubName: Full=Yes-associated protein isoform 9 {ECO:0000313|EMBL:CCI79622.1}; Flags: Fragment;+++[Q86T74_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451O0517 {ECO:0000313|EMBL:CAD89963.1}; Flags: Fragment;"]
[10417,"'SPON2'",1189,1350,1412,1317,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0001530///lipopolysaccharide binding+++GO:0003823///antigen binding","GO:0007411///axon guidance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0002448///mast cell mediated immunity+++GO:0008228///opsonization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0051607///defense response to virus+++GO:0032496///response to lipopolysaccharide+++GO:0007155///cell adhesion+++GO:0043152///induction of bacterial agglutination+++GO:0042742///defense response to bacterium+++GO:0050832///defense response to fungus+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0002376///immune system process","spondin 2","[SPON2_HUMAN|Reviewed]RecName: Full=Spondin-2; AltName: Full=Differentially expressed in cancerous and non-cancerous lung cells 1; Short=DIL-1; AltName: Full=Mindin; Flags: Precursor;+++[A0A1Y8ELY7_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421858}; Flags: Fragment;+++[D6RA41_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000423414}; Flags: Fragment;+++[D6RB12_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000424542}; Flags: Fragment;+++[D6RBY3_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000422516}; Flags: Fragment;+++[D6REX2_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421634}; Flags: Fragment;+++[D6RFY9_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421379}; Flags: Fragment;+++[D6RIH5_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000425871}; Flags: Fragment;"]
[10418,"'SPON1'",2,0,1,1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region","GO:0005201///extracellular matrix structural constituent+++GO:0050693///LBD domain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:1902993///positive regulation of amyloid precursor protein catabolic process+++GO:0010954///positive regulation of protein processing+++GO:1902430///negative regulation of amyloid-beta formation+++GO:0032092///positive regulation of protein binding","spondin 1","[SPON1_HUMAN|Reviewed]RecName: Full=Spondin-1; AltName: Full=F-spondin; AltName: Full=Vascular smooth muscle cell growth-promoting factor; Flags: Precursor;+++[Q3ZCT3_HUMAN|Unreviewed]SubName: Full=SPON1 protein {ECO:0000313|EMBL:AAH41974.1}; Flags: Fragment;"]
[10419,"'PRMT5'",1073,1169,1219,1153.66666666667,"04111///Cell cycle - yeast+++04011///MAPK signaling pathway - yeast+++03013///RNA transport",null,null,"R11220///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11218///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0035097///histone methyltransferase complex+++GO:0005737///cytoplasm+++GO:0034709///methylosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0008327///methyl-CpG binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0003714///transcription corepressor activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0044020///histone methyltransferase activity (H4-R3 specific)+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0070888///E-box binding+++GO:0005515///protein binding","GO:0006325///chromatin organization+++GO:1904992///positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0044030///regulation of DNA methylation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0042118///endothelial cell activation+++GO:0000387///spliceosomal snRNP assembly+++GO:0097421///liver regeneration+++GO:0043985///histone H4-R3 methylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0018216///peptidyl-arginine methylation+++GO:0008283///cell proliferation+++GO:0006479///protein methylation+++GO:0045596///negative regulation of cell differentiation+++GO:0048511///rhythmic process+++GO:0006353///DNA-templated transcription, termination+++GO:0032922///circadian regulation of gene expression+++GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0035246///peptidyl-arginine N-methylation+++GO:0032259///methylation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0034969///histone arginine methylation+++GO:0007088///regulation of mitotic nuclear division+++GO:0090161///Golgi ribbon formation","protein arginine methyltransferase 5","[ANM5_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 5; EC=2.1.1.320 {ECO:0000269|PubMed:21081503, ECO:0000269|PubMed:23071334}; AltName: Full=72 kDa ICln-binding protein; AltName: Full=Histone-arginine N-methyltransferase PRMT5; AltName: Full=Jak-binding protein 1; AltName: Full=Shk1 kinase-binding protein 1 homolog; Short=SKB1 homolog; Short=SKB1Hs; Contains: RecName: Full=Protein arginine N-methyltransferase 5, N-terminally processed;+++[B4DV00_HUMAN|Unreviewed]RecName: Full=Protein arginine N-methyltransferase 5 {ECO:0000256|PIRNR:PIRNR015894}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR015894};+++[C9JSX3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000409482}; Flags: Fragment;+++[G3V2F5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450633};+++[G3V2L6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450737}; Flags: Fragment;+++[G3V2X6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450919}; Flags: Fragment;+++[G3V3A3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451127};+++[G3V507_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452102};+++[G3V580_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452218}; Flags: Fragment;+++[G3V5L5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452411}; Flags: Fragment;+++[G3V5T6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452509}; Flags: Fragment;+++[H0YJ77_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450956}; Flags: Fragment;+++[H0YJD3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451245}; Flags: Fragment;+++[H0YJX6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452409}; Flags: Fragment;+++[H0YJY6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452501}; Flags: Fragment;+++[H7BZ44_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000387663}; Flags: Fragment;"]
[10420,"'TESK2'",25,32,25,27.3333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding","GO:0030036///actin cytoskeleton organization+++GO:0048041///focal adhesion assembly+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis","testis associated actin remodelling kinase 2","[TESK2_HUMAN|Reviewed]RecName: Full=Dual specificity testis-specific protein kinase 2; EC=2.7.12.1; AltName: Full=Testicular protein kinase 2;+++[B4DFN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58133, highly similar to Dual specificity testis-specific protein kinase 2 {ECO:0000313|EMBL:BAG57493.1};+++[D3DPZ7_HUMAN|Unreviewed]SubName: Full=Testis-specific kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAX06988.1};"]
[10421,"'CD2BP2'",722,741,872,778.333333333333,"03015///mRNA surveillance pathway",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005682///U5 snRNP+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0010923///negative regulation of phosphatase activity+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0006397///mRNA processing","CD2 cytoplasmic tail binding protein 2","[CD2B2_HUMAN|Reviewed]RecName: Full=CD2 antigen cytoplasmic tail-binding protein 2; Short=CD2 cytoplasmic domain-binding protein 2; Short=CD2 tail-binding protein 2; AltName: Full=U5 snRNP 52K protein; Short=U5-52K;+++[A0A024QZC1_HUMAN|Unreviewed]SubName: Full=CD2 antigen (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW52261.1}; SubName: Full=CD2 binding protein 2 isoform 1 {ECO:0000313|EMBL:ALQ33976.1};+++[A0A0S2Z5J7_HUMAN|Unreviewed]SubName: Full=CD2 binding protein 2 isoform 2 {ECO:0000313|EMBL:ALQ33977.1}; Flags: Fragment;"]
[10422,"'UBAC1'",412,500,449,453.666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0016567///protein ubiquitination","UBA domain containing 1","[UBAC1_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated domain-containing protein 1; Short=UBA domain-containing protein 1; AltName: Full=E3 ubiquitin-protein ligase subunit KPC2; AltName: Full=Glialblastoma cell differentiation-related protein 1; AltName: Full=Kip1 ubiquitination-promoting complex protein 2;+++[A0A024R8I2_HUMAN|Unreviewed]SubName: Full=Ubiquitin associated domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW88190.1};+++[A0A140VK64_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 64 {ECO:0000313|EMBL:AEE61201.1};"]
[10423,"'CDIPT'",1735,1768,1819,1774,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00564///Glycerophospholipid metabolism+++00562///Inositol phosphate metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase   CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0019992///diacylglycerol binding+++GO:0043178///alcohol binding+++GO:0030246///carbohydrate binding+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046341///CDP-diacylglycerol metabolic process","CDP-diacylglycerol--inositol 3-phosphatidyltransferase","[CDIPT_HUMAN|Reviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase; EC=2.7.8.11; AltName: Full=Phosphatidylinositol synthase; Short=PI synthase; Short=PtdIns synthase;+++[A8K3L7_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KSW0_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KY94_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000455042}; SubName: Full=cDNA FLJ16129 fis, clone BRACE2039823, highly similar to CDP-diacylglycerol--inositol3-phosphatidyltransferase {ECO:0000313|EMBL:BAG54756.1};+++[H3BTJ7_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457207};+++[H3BUR9_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457766};"]
[10424,"'PGRMC2'",1861,1698,1883,1814,{"$nulls":4},"GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0005496///steroid binding+++GO:0003707///steroid hormone receptor activity","GO:0043401///steroid hormone mediated signaling pathway","progesterone receptor membrane component 2","[PGRC2_HUMAN|Reviewed]RecName: Full=Membrane-associated progesterone receptor component 2; AltName: Full=Progesterone membrane-binding protein; AltName: Full=Steroid receptor protein DG6;+++[D3DNX8_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475242}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_a {ECO:0000313|EMBL:EAX05179.1};+++[U3KQ70_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475603}; Flags: Fragment;+++[U3KQM0_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000476010}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_c {ECO:0000313|EMBL:EAX05182.1};"]
[10425,"'ARIH2'",838.53,874,839.69,850.74,{"$nulls":4},"GO:0005634///nucleus+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0016740///transferase activity","GO:0016567///protein ubiquitination+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0007275///multicellular organism development+++GO:0070936///protein K48-linked ubiquitination+++GO:0048588///developmental cell growth+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination","ariadne RBR E3 ubiquitin protein ligase 2","[ARI2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase ARIH2; Short=ARI-2; Short=Protein ariadne-2 homolog; EC=2.3.2.31 {ECO:0000269|PubMed:16118314, ECO:0000269|PubMed:17646546, ECO:0000269|PubMed:19340006}; AltName: Full=RING-type E3 ubiquitin transferase ARIH2 {ECO:0000305}; AltName: Full=Triad1 protein {ECO:0000303|PubMed:10422847};+++[C9JAU2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000406063}; Flags: Fragment;+++[C9JBC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000397225}; Flags: Fragment;+++[C9JCL4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000404838}; Flags: Fragment;+++[C9JZ71_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000399788}; Flags: Fragment;+++[F8WCS4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000403845};+++[Q53ET9_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;+++[Q6IBL8_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};"]
[10426,"'TUBGCP3'",287,212,202,233.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005816///spindle pole body+++GO:0000923///equatorial microtubule organizing center+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000930///gamma-tubulin complex+++GO:0008275///gamma-tubulin small complex+++GO:0005827///polar microtubule+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005874///microtubule+++GO:0016020///membrane","GO:0005198///structural molecule activity+++GO:0051011///microtubule minus-end binding+++GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007020///microtubule nucleation+++GO:0051321///meiotic cell cycle+++GO:0090307///mitotic spindle assembly+++GO:0000226///microtubule cytoskeleton organization+++GO:0007338///single fertilization+++GO:0051415///microtubule nucleation by interphase microtubule organizing center+++GO:0031122///cytoplasmic microtubule organization","tubulin gamma complex associated protein 3","[GCP3_HUMAN|Reviewed]RecName: Full=Gamma-tubulin complex component 3; Short=GCP-3; Short=hGCP3; AltName: Full=Gamma-ring complex protein 104 kDa; Short=h104p; Short=hGrip104; AltName: Full=Spindle pole body protein Spc98 homolog; Short=hSpc98;+++[A0A087WU06_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};+++[A0A087WZV5_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX56_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX63_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[B4DYP7_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};"]
[10427,"'SEC24B'",958,843,591,797.333333333333,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0000139///Golgi membrane+++GO:0030127///COPII vesicle coat+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1901301///regulation of cargo loading into COPII-coated vesicle+++GO:0001843///neural tube closure+++GO:0015031///protein transport+++GO:0072358///cardiovascular system development+++GO:0002093///auditory receptor cell morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060425///lung morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006886///intracellular protein transport+++GO:0061156///pulmonary artery morphogenesis+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0021747///cochlear nucleus development+++GO:0035909///aorta morphogenesis+++GO:0016192///vesicle-mediated transport+++GO:0090178///regulation of establishment of planar polarity involved in neural tube closure+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060463///lung lobe morphogenesis","SEC24 homolog B, COPII coat complex component","[SC24B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24B {ECO:0000305}; AltName: Full=SEC24-related protein B;+++[B4DTM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61391, highly similar to Protein transport protein Sec24B {ECO:0000313|EMBL:BAG62038.1};"]
[10428,"'CFDP1'",466,449,501,472,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0005575///cellular_component+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore","GO:0003674///molecular_function","GO:0007275///multicellular organism development+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:0008150///biological_process+++GO:0008360///regulation of cell shape+++GO:0007155///cell adhesion+++GO:0042127///regulation of cell proliferation","craniofacial development protein 1","[CFDP1_HUMAN|Reviewed]RecName: Full=Craniofacial development protein 1; AltName: Full=Bucentaur;+++[A0A087WXQ2_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000481200}; Flags: Fragment;+++[A0A0H5APX3_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91204.1};+++[A0A0H5AUJ9_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91203.1};+++[A0A0H5B9V7_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91205.1};+++[H3BQ17_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000455564}; Flags: Fragment;+++[J3KT89_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000462862}; Flags: Fragment;"]
[1043,"'CD52'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0031225///anchored component of membrane+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0016020///membrane+++GO:0097225///sperm midpiece+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane",null,"GO:0045730///respiratory burst+++GO:0007204///positive regulation of cytosolic calcium ion concentration","CD52 molecule","[CD52_HUMAN|Reviewed]RecName: Full=CAMPATH-1 antigen; AltName: Full=CDw52; AltName: Full=Cambridge pathology 1 antigen; AltName: Full=Epididymal secretory protein E5; AltName: Full=Human epididymis-specific protein 5; Short=He5; AltName: CD_antigen=CD52; Flags: Precursor;+++[Q6IBD0_HUMAN|Unreviewed]SubName: Full=CD52 antigen (CAMPATH-1 antigen) {ECO:0000313|EMBL:EAX07822.1}; SubName: Full=CDW52 antigen (CAMPATH-1 antigen) {ECO:0000313|EMBL:AAP35780.1}; SubName: Full=CDW52 protein {ECO:0000313|EMBL:CAG33155.1};+++[Q9UJ81_HUMAN|Unreviewed]SubName: Full=CD52 protein {ECO:0000313|EMBL:CAB51285.1}; Flags: Fragment;+++[V9HWN9_HUMAN|Unreviewed]SubName: Full=CD52 antigen {ECO:0000313|EMBL:AJC19276.1}; SubName: Full=Epididymis secretory sperm binding protein Li 171mP {ECO:0000313|EMBL:ACS44650.1};"]
[10430,"'TMEM147'",1413,1868,1931,1737.33333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0032991///protein-containing complex","GO:0005515///protein binding",null,"transmembrane protein 147","[TM147_HUMAN|Reviewed]RecName: Full=Transmembrane protein 147; AltName: Full=Protein NIFIE 14;+++[A8MU21_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000376041};+++[K7ELX3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000466262};"]
[10432,"'RBM14'",1036.52,959.86,1015.62,1004,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0003676///nucleic acid binding+++GO:0030674///protein binding, bridging+++GO:0003723///RNA binding+++GO:0003712///transcription coregulator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0002218///activation of innate immune response+++GO:0006281///DNA repair+++GO:0045087///innate immune response+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0006310///DNA recombination+++GO:0016575///histone deacetylation+++GO:0098534///centriole assembly+++GO:0046600///negative regulation of centriole replication+++GO:0002376///immune system process+++GO:0009725///response to hormone+++GO:0042921///glucocorticoid receptor signaling pathway","RNA binding motif protein 14","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0S2Z4Z0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 1 {ECO:0000313|EMBL:ALQ33978.1}; Flags: Fragment;+++[A0A0S2Z567_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 2 {ECO:0000313|EMBL:ALQ33979.1};+++[A0A0S2Z5V2_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 3 {ECO:0000313|EMBL:ALQ33980.1};+++[B8ZZ74_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000386518};+++[F8WDX3_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000414650};"]
[10434,"'LYPLA1'",515,506,425,482,"05231///Choline metabolism in cancer+++00564///Glycerophospholipid metabolism",null,null,"R02746///1-Acyl-sn-glycero-3-phosphocholine acylhydrolase   1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid+++R03416///1-Acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase   1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine","GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0016298///lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0008474///palmitoyl-(protein) hydrolase activity","GO:0042997///negative regulation of Golgi to plasma membrane protein transport+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0006631///fatty acid metabolic process+++GO:0002084///protein depalmitoylation+++GO:0006629///lipid metabolic process","lysophospholipase I","[LYPA1_HUMAN|Reviewed]RecName: Full=Acyl-protein thioesterase 1; Short=APT-1; Short=hAPT1; EC=3.1.2.-; AltName: Full=Lysophospholipase 1; AltName: Full=Lysophospholipase I; Short=LPL-I; Short=LysoPLA I;+++[A0A087X1K9_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000484280};+++[B4DP64_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000482430}; SubName: Full=cDNA FLJ52008, highly similar to Acyl-protein thioesterase 1 {ECO:0000313|EMBL:BAG60476.1};+++[E5RFT6_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000427967};+++[E5RGR0_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428729}; Flags: Fragment;+++[E5RI35_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000430791}; Flags: Fragment;+++[E5RJ48_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428306}; Flags: Fragment;+++[Q6IAQ1_HUMAN|Unreviewed]SubName: Full=LYPLA1 protein {ECO:0000313|EMBL:CAG33384.1}; SubName: Full=Lysophospholipase I, isoform CRA_a {ECO:0000313|EMBL:EAW86742.1}; SubName: Full=cDNA FLJ78542, highly similar to Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAF82089.1}; SubName: Full=cDNA, FLJ94339, Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAG36480.1};"]
[10435,"'CDC42EP2'",360,394,529,427.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0045335///phagocytic vesicle+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017049///GTP-Rho binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0001515///opioid peptide activity","GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity+++GO:0007266///Rho protein signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0008360///regulation of cell shape+++GO:0010469///regulation of signaling receptor activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007015///actin filament organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031274///positive regulation of pseudopodium assembly","CDC42 effector protein 2","[BORG1_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 2; AltName: Full=Binder of Rho GTPases 1;"]
[10436,"'EMG1'",191,168,251,203.333333333333,"03008///Ribosome biogenesis in eukaryotes","H00616///Bowen-Conradi syndrome (BCS)",null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0070037///rRNA (pseudouridine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0019843///rRNA binding+++GO:0016740///transferase activity","GO:0042274///ribosomal small subunit biogenesis+++GO:0042254///ribosome biogenesis+++GO:0001824///blastocyst development+++GO:0017126///nucleologenesis+++GO:0032259///methylation+++GO:0070475///rRNA base methylation+++GO:0006364///rRNA processing","EMG1, N1-specific pseudouridine methyltransferase","[NEP1_HUMAN|Reviewed]RecName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000305|PubMed:20047967}; EC=2.1.1.- {ECO:0000269|PubMed:20047967}; AltName: Full=18S rRNA (pseudouridine(1248)-N1)-methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=18S rRNA Psi1248 methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=Nucleolar protein EMG1 homolog {ECO:0000250|UniProtKB:Q06287}; AltName: Full=Protein C2f {ECO:0000303|PubMed:9074930}; AltName: Full=Ribosome biogenesis protein NEP1 {ECO:0000303|PubMed:20047967};+++[A0A087WVM7_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000479546}; Flags: Fragment;+++[A0A087WWQ2_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000480420}; Flags: Fragment;+++[A0A0U3B3H7_HUMAN|Unreviewed]SubName: Full=EMG1 N1-specific pseudouridine methyl transferase {ECO:0000313|EMBL:ALT07792.1}; Flags: Fragment;+++[B4DP65_HUMAN|Unreviewed]SubName: Full=EMG1 nucleolar protein homolog (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW88694.1}; SubName: Full=cDNA FLJ56921, highly similar to Probable ribosome biogenesis protein NEP1 {ECO:0000313|EMBL:BAG60477.1};+++[V9GYP5_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000476966}; Flags: Fragment;"]
[10437,"'IFI30'",816,838,912,855.333333333333,"04612///Antigen processing and presentation",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030054///cell junction+++GO:0043202///lysosomal lumen+++GO:0005764///lysosome+++GO:0005576///extracellular region+++GO:0005829///cytosol","GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0016667///oxidoreductase activity, acting on a sulfur group of donors","GO:0055114///oxidation-reduction process+++GO:0002376///immune system process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I","IFI30, lysosomal thiol reductase","[GILT_HUMAN|Reviewed]RecName: Full=Gamma-interferon-inducible lysosomal thiol reductase; EC=1.8.-.- {ECO:0000269|PubMed:10639150, ECO:0000269|PubMed:10852914}; AltName: Full=Gamma-interferon-inducible protein IP-30; AltName: Full=Legumaturain; Flags: Precursor;+++[A0A024R7N7_HUMAN|Unreviewed]SubName: Full=Interferon, gamma-inducible protein 30, isoform CRA_b {ECO:0000313|EMBL:EAW84665.1};+++[M0QZG3_HUMAN|Unreviewed]SubName: Full=Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000313|Ensembl:ENSP00000470527}; Flags: Fragment;+++[Q96P99_HUMAN|Unreviewed]SubName: Full=Interferon gamma-inducible protein 30 {ECO:0000313|EMBL:AAL02170.1}; Flags: Fragment;"]
[10438,"'C1D'",144,144,162,150,"03018///RNA degradation",{"$nulls":3},"GO:0017053///transcriptional repressor complex+++GO:0005769///early endosome+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0098797///plasma membrane protein complex+++GO:0005886///plasma membrane+++GO:0030666///endocytic vesicle membrane+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005905///clathrin-coated pit+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0030136///clathrin-coated vesicle+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex","GO:0044877///protein-containing complex binding+++GO:0003677///DNA binding+++GO:0016964///alpha-2 macroglobulin receptor activity+++GO:0002020///protease binding+++GO:0042954///lipoprotein transporter activity+++GO:0032050///clathrin heavy chain binding+++GO:0038023///signaling receptor activity+++GO:0003714///transcription corepressor activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0030226///apolipoprotein receptor activity+++GO:0005509///calcium ion binding+++GO:0070325///lipoprotein particle receptor binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0034185///apolipoprotein binding","GO:0042157///lipoprotein metabolic process+++GO:0006915///apoptotic process+++GO:0006364///rRNA processing+++GO:0032092///positive regulation of protein binding+++GO:0051222///positive regulation of protein transport+++GO:0008283///cell proliferation+++GO:0032374///regulation of cholesterol transport+++GO:0010942///positive regulation of cell death+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0042953///lipoprotein transport+++GO:0006897///endocytosis+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0010875///positive regulation of cholesterol efflux+++GO:0002265///astrocyte activation involved in immune response+++GO:0006629///lipid metabolic process+++GO:0000460///maturation of 5.8S rRNA+++GO:0035909///aorta morphogenesis+++GO:0043277///apoptotic cell clearance+++GO:0045732///positive regulation of protein catabolic process+++GO:0051246///regulation of protein metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010977///negative regulation of neuron projection development+++GO:0031623///receptor internalization+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905167///positive regulation of lysosomal protein catabolic process+++GO:0032429///regulation of phospholipase A2 activity+++GO:1904646///cellular response to amyloid-beta+++GO:0006898///receptor-mediated endocytosis+++GO:0001523///retinoid metabolic process+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0021987///cerebral cortex development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0045056///transcytosis+++GO:0097242///amyloid-beta clearance+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0006909///phagocytosis+++GO:0032370///positive regulation of lipid transport+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0045807///positive regulation of endocytosis","C1D nuclear receptor corepressor","[C1D_HUMAN|Reviewed]RecName: Full=Nuclear nucleic acid-binding protein C1D; Short=hC1D;+++[H0YJ88_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451012}; Flags: Fragment;+++[H0YJI8_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451622}; Flags: Fragment;+++[J3KPZ4_HUMAN|Unreviewed]SubName: Full=Nuclear nucleic acid-binding protein C1D {ECO:0000313|Ensembl:ENSP00000384304};+++[L0R6J6_HUMAN|Unreviewed]SubName: Full=Alternative protein LRP1 {ECO:0000313|EMBL:CCO13765.1};+++[Q6PJ72_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH21204.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451737};+++[Q7Z7K9_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH52593.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451449};"]
[10439,"'OLFM1'",75,53,52,60,{"$nulls":4},"GO:0045202///synapse+++GO:0043204///perikaryon+++GO:0005615///extracellular space+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0044295///axonal growth cone+++GO:0005623///cell+++GO:0005576///extracellular region","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0030516///regulation of axon extension+++GO:0023041///neuronal signal transduction+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0003190///atrioventricular valve formation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression","olfactomedin 1","[NOE1_HUMAN|Reviewed]RecName: Full=Noelin; AltName: Full=Neuronal olfactomedin-related ER localized protein; AltName: Full=Olfactomedin-1; Flags: Precursor;+++[F5GZQ2_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000444296}; Flags: Fragment;+++[F5H810_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000443806}; Flags: Fragment;+++[F8W870_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000340318}; Flags: Fragment;+++[H0YFB9_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000437906}; Flags: Fragment;+++[Q5VZL8_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360866};+++[Q6IMJ6_HUMAN|Unreviewed]SubName: Full=NOELIN1_V5 {ECO:0000313|EMBL:DAA01549.1}; SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360864};+++[Q6IMJ7_HUMAN|Unreviewed]SubName: Full=NOELIN1_V4 {ECO:0000313|EMBL:DAA01548.1}; SubName: Full=Olfactomedin 1, isoform CRA_d {ECO:0000313|EMBL:EAW88145.1};+++[Q6IMJ8_HUMAN|Unreviewed]SubName: Full=NOELIN1_V1 {ECO:0000313|EMBL:DAA01545.1}; SubName: Full=Olfactomedin 1, isoform CRA_c {ECO:0000313|EMBL:EAW88144.1};+++[Q96BL8_HUMAN|Unreviewed]SubName: Full=OLFM1 protein {ECO:0000313|EMBL:AAH15437.2}; Flags: Fragment;+++[Q9BWJ9_HUMAN|Unreviewed]SubName: Full=Olfactomedin 1 {ECO:0000313|EMBL:AAH00189.1}; SubName: Full=Olfactomedin 1, isoform CRA_b {ECO:0000313|EMBL:EAW88143.1};"]
[1044,"'CDX1'",21,14,14,16.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008327///methyl-CpG binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding","GO:0009887///animal organ morphogenesis+++GO:0014807///regulation of somitogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060349///bone morphogenesis+++GO:0030154///cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009952///anterior/posterior pattern specification+++GO:0007389///pattern specification process+++GO:0007275///multicellular organism development+++GO:0045944///positive regulation of transcription by RNA polymerase II","caudal type homeobox 1","[CDX1_HUMAN|Reviewed]RecName: Full=Homeobox protein CDX-1; AltName: Full=Caudal-type homeobox protein 1;+++[A0A087WTJ6_HUMAN|Unreviewed]SubName: Full=Homeobox protein CDX-1 {ECO:0000313|Ensembl:ENSP00000477928};+++[Q14DX0_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96249.1};+++[Q4VAU3_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96252.2};+++[Q4VAU5_HUMAN|Unreviewed]SubName: Full=CDX1 protein {ECO:0000313|EMBL:AAH96250.1};"]
[10440,"'TIMM17A'",355,333,337,341.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex","GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0010954///positive regulation of protein processing+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0071806///protein transmembrane transport+++GO:0006886///intracellular protein transport+++GO:0006626///protein targeting to mitochondrion","translocase of inner mitochondrial membrane 17A","[TI17A_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-A; AltName: Full=Inner membrane preprotein translocase Tim17a;+++[A0A024R9A5_HUMAN|Unreviewed]SubName: Full=Translocase of inner mitochondrial membrane 17 homolog A (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW91385.1};+++[A0PJ74_HUMAN|Unreviewed]SubName: Full=TIMM17A protein {ECO:0000313|EMBL:AAH16817.1}; Flags: Fragment;+++[Q7RU05_HUMAN|Unreviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM17 {ECO:0000256|RuleBase:RU364008};"]
[10443,"'N4BP2L2'",347,353,348,349.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex","GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1902037///negative regulation of hematopoietic stem cell differentiation+++GO:1902035///positive regulation of hematopoietic stem cell proliferation","NEDD4 binding protein 2 like 2","[N42L2_HUMAN|Reviewed]RecName: Full=NEDD4-binding protein 2-like 2; AltName: Full=Phosphonoformate immuno-associated protein 5;+++[A0A024RDV2_HUMAN|Unreviewed]SubName: Full=HCG32190, isoform CRA_b {ECO:0000313|EMBL:EAX08515.1};+++[B4DPY1_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000350104}; SubName: Full=cDNA FLJ55497 {ECO:0000313|EMBL:BAG60743.1};+++[D6R968_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000423362}; Flags: Fragment;+++[Q96KV2_HUMAN|Unreviewed]SubName: Full=92M18.3 (Novel protein) {ECO:0000313|EMBL:CAC94790.1};+++[Q9Y3H6_HUMAN|Unreviewed]SubName: Full=HCG33128, isoform CRA_a {ECO:0000313|EMBL:EAX08509.1};"]
[10444,"'ZER1'",2618,2824,2865,2769,{"$nulls":4},"GO:0031462///Cul2-RING ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:0016567///protein ubiquitination","zyg-11 related cell cycle regulator","[ZER1_HUMAN|Reviewed]RecName: Full=Protein zer-1 homolog; AltName: Full=Hzyg; AltName: Full=Zyg-11 homolog B-like protein; AltName: Full=Zyg11b-like protein;+++[A0A024R8B0_HUMAN|Unreviewed]SubName: Full=Zyg-11 homolog B (C. elegans)-like, isoform CRA_b {ECO:0000313|EMBL:EAW87831.1};+++[Q05BR7_HUMAN|Unreviewed]SubName: Full=ZER1 protein {ECO:0000313|EMBL:AAH33884.1}; Flags: Fragment;+++[X6RC68_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000389271}; Flags: Fragment;+++[X6RD87_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000393051}; Flags: Fragment;"]
[10445,"'MCRS1'",801,819,936,852,"05168///Herpes simplex infection",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0044545///NSL complex+++GO:0043204///perikaryon+++GO:0030425///dendrite+++GO:0000123///histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0031011///Ino80 complex+++GO:0005634///nucleus+++GO:0071339///MLL1 complex+++GO:0005730///nucleolus+++GO:0005844///polysome","GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0034046///poly(G) binding+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)+++GO:0010521///telomerase inhibitor activity+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0008266///poly(U) RNA binding+++GO:0005515///protein binding+++GO:0002151///G-quadruplex RNA binding","GO:0006310///DNA recombination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006464///cellular protein modification process+++GO:0043982///histone H4-K8 acetylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043981///histone H4-K5 acetylation+++GO:0051974///negative regulation of telomerase activity+++GO:0016579///protein deubiquitination+++GO:0043984///histone H4-K16 acetylation+++GO:0006281///DNA repair+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:0006325///chromatin organization+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening","microspherule protein 1","[MCRS1_HUMAN|Reviewed]RecName: Full=Microspherule protein 1; AltName: Full=58 kDa microspherule protein; AltName: Full=Cell cycle-regulated factor p78; AltName: Full=INO80 complex subunit J; AltName: Full=MCRS2;+++[A0A024R134_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1, isoform CRA_d {ECO:0000313|EMBL:EAW58079.1};+++[F8VP44_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000450352}; Flags: Fragment;+++[F8VVA6_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000449343}; Flags: Fragment;+++[F8VZC2_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447739};+++[F8W0I9_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447592}; Flags: Fragment;+++[F8W126_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447514}; Flags: Fragment;+++[H0YI67_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448700}; Flags: Fragment;+++[H0YIA0_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448947}; Flags: Fragment;+++[L8E8H6_HUMAN|Unreviewed]SubName: Full=Alternative protein MCRS1 {ECO:0000313|EMBL:CCQ43031.1};"]
[10446,"'LRRN2'",3255,2337,2672,2754.66666666667,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005615///extracellular space","GO:0038023///signaling receptor activity","GO:0007165///signal transduction+++GO:0007155///cell adhesion","leucine rich repeat neuronal 2","[LRRN2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat neuronal protein 2; AltName: Full=Glioma amplified on chromosome 1 protein; AltName: Full=Leucine-rich repeat neuronal protein 5; Flags: Precursor;+++[A0A024R993_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat neuronal 5, isoform CRA_a {ECO:0000313|EMBL:EAW91521.1};"]
[10447,"'FAM3C'",540,507,499,515.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031089///platelet dense granule lumen+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle","GO:0005125///cytokine activity+++GO:0005515///protein binding","GO:0010469///regulation of signaling receptor activity+++GO:0008150///biological_process+++GO:0045721///negative regulation of gluconeogenesis+++GO:0007275///multicellular organism development+++GO:0002576///platelet degranulation","family with sequence similarity 3 member C","[FAM3C_HUMAN|Reviewed]RecName: Full=Protein FAM3C; AltName: Full=Interleukin-like EMT inducer; Flags: Precursor;+++[C9JMN4_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000408636}; Flags: Fragment;+++[C9JP35_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000414940}; Flags: Fragment;"]
[10449,"'ACAA2'",714,645,732,697,"01212///Fatty acid metabolism+++01100///Metabolic pathways+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++00280///Valine, leucine and isoleucine degradation+++01130///Biosynthesis of antibiotics+++00062///Fatty acid elongation",null,"M00087///beta-Oxidation+++M00085///Fatty acid biosynthesis, elongation, mitochondria","R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase   Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase   Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase   Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00391///Acyl-CoA:acetyl-CoA C-acyltransferase   Acyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoacyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase   Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase   Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase   Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA   Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA","GO:0005759///mitochondrial matrix+++GO:0016459///myosin complex+++GO:0005739///mitochondrion","GO:0003824///catalytic activity+++GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0003774///motor activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding","GO:0006629///lipid metabolic process+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0071456///cellular response to hypoxia+++GO:0006635///fatty acid beta-oxidation+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","acetyl-CoA acyltransferase 2","[THIM_HUMAN|Reviewed]RecName: Full=3-ketoacyl-CoA thiolase, mitochondrial; EC=2.3.1.16; AltName: Full=Acetyl-CoA acyltransferase; AltName: Full=Beta-ketothiolase; AltName: Full=Mitochondrial 3-oxoacyl-CoA thiolase; AltName: Full=T1;+++[A0A024R269_HUMAN|Unreviewed]SubName: Full=Acetyl-Coenzyme A acyltransferase 2 (Mitochondrial 3-oxoacyl-Coenzyme A thiolase), isoform CRA_d {ECO:0000313|EMBL:EAW62956.1};+++[A0A0B4J2A4_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466015};+++[B3KNP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30111 fis, clone BNGH42000360, highly similar to 3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|EMBL:BAG51410.1};+++[K7EJ68_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465045}; Flags: Fragment;+++[K7EJB1_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465095}; Flags: Fragment;+++[K7EME0_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466466};+++[K7ER88_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000468157}; Flags: Fragment;"]
[10450,"'PPIE'",365,370,356,363.666666666667,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000974///Prp19 complex+++GO:0034774///secretory granule lumen+++GO:0071013///catalytic step 2 spliceosome+++GO:0005576///extracellular region+++GO:0005681///spliceosomal complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0051082///unfolded protein binding+++GO:0016853///isomerase activity+++GO:0003676///nucleic acid binding+++GO:0016018///cyclosporin A binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008143///poly(A) binding","GO:0006457///protein folding+++GO:0043312///neutrophil degranulation+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0045070///positive regulation of viral genome replication+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0006355///regulation of transcription, DNA-templated","peptidylprolyl isomerase E","[PPIE_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase E; Short=PPIase E; EC=5.2.1.8 {ECO:0000269|PubMed:18258190, ECO:0000269|PubMed:20541251, ECO:0000269|PubMed:20677832, ECO:0000269|PubMed:8977107}; AltName: Full=Cyclophilin E; AltName: Full=Cyclophilin-33 {ECO:0000303|PubMed:8977107}; AltName: Full=Rotamase E;+++[B3KSZ1_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PEQ6_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PIB0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000436689}; Flags: Fragment;+++[E9PK21_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000431714};+++[E9PKY5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[E9PMH0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434989};+++[H0YCV4_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000432396}; Flags: Fragment;+++[H0YE31_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434888}; Flags: Fragment;"]
[10451,"'VAV3'",111,106,81,99.3333333333333,"04670///Leukocyte transendothelial migration+++04664///Fc epsilon RI signaling pathway+++04662///B cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04666///Fc gamma R-mediated phagocytosis+++04062///Chemokine signaling pathway+++04660///T cell receptor signaling pathway+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005096///GTPase activator activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0001525///angiogenesis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0050853///B cell receptor signaling pathway+++GO:0030032///lamellipodium assembly+++GO:0030031///cell projection assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0016477///cell migration+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0043087///regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008361///regulation of cell size+++GO:0009967///positive regulation of signal transduction+++GO:0048013///ephrin receptor signaling pathway+++GO:0006906///vesicle fusion+++GO:0042493///response to drug+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030593///neutrophil chemotaxis+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0030168///platelet activation+++GO:0030890///positive regulation of B cell proliferation+++GO:0007229///integrin-mediated signaling pathway+++GO:0045785///positive regulation of cell adhesion","vav guanine nucleotide exchange factor 3","[VAV3_HUMAN|Reviewed]RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3;+++[A0A2X0U2Q1_HUMAN|Unreviewed]SubName: Full=VAV3 {ECO:0000313|EMBL:SPT35811.1}; Flags: Fragment;+++[E9PMJ5_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000434944};+++[H0YCG7_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000431544}; Flags: Fragment;+++[H0YDG2_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000433559}; Flags: Fragment;"]
[10452,"'TOMM40'",1243,1239,1358,1280,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0046930///pore complex+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0005829///cytosol","GO:0008320///protein transmembrane transporter activity+++GO:0015288///porin activity+++GO:0005515///protein binding","GO:0006626///protein targeting to mitochondrion+++GO:0055085///transmembrane transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0006811///ion transport","translocase of outer mitochondrial membrane 40","[TOM40_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM40 homolog; AltName: Full=Protein Haymaker; AltName: Full=Translocase of outer membrane 40 kDa subunit homolog; AltName: Full=p38.5;+++[K7EJ57_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465032}; Flags: Fragment;+++[K7EKG4_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465608}; Flags: Fragment;+++[K7EKG6_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465611}; Flags: Fragment;"]
[10454,"'TAB1'",787,840,871,832.666666666667,"05145///Toxoplasmosis+++05169///Epstein-Barr virus infection+++05168///Herpes simplex infection+++05140///Leishmaniasis+++04620///Toll-like receptor signaling pathway+++04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway+++04380///Osteoclast differentiation",null,"M00686///Toll-like receptor signaling",null,"GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016607///nuclear speck","GO:0003824///catalytic activity+++GO:0008047///enzyme activator activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0019209///kinase activator activity+++GO:0016301///kinase activity+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:0005515///protein binding","GO:0030324///lung development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0001701///in utero embryonic development+++GO:0000185///activation of MAPKKK activity+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0035904///aorta development+++GO:0003279///cardiac septum development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006470///protein dephosphorylation+++GO:0000187///activation of MAPK activity+++GO:0060976///coronary vasculature development+++GO:0016579///protein deubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0003007///heart morphogenesis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0007254///JNK cascade","TGF-beta activated kinase 1 (MAP3K7) binding protein 1","[TAB1_HUMAN|Reviewed]RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; AltName: Full=TGF-beta-activated kinase 1-binding protein 1; Short=TAK1-binding protein 1;+++[A8K6K3_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 7 interacting protein 1, isoform CRA_f {ECO:0000313|EMBL:EAW60330.1}; SubName: Full=cDNA FLJ78598, highly similar to Homo sapiens mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (MAP3K7IP1), transcript variant alpha, mRNA {ECO:0000313|EMBL:BAF84357.1}; SubName: Full=cDNA, FLJ92811, Homo sapiens mitogen-activated protein kinase kinase kinase 7interacting protein 1 (MAP3K7IP1), mRNA {ECO:0000313|EMBL:BAG35363.1};"]
[10455,"'ECI2'",299,250,304,284.333333333333,"04146///Peroxisome+++00071///Fatty acid degradation",null,null,"R04756///cis,cis-3,6-Dodecadienoyl-CoA delta3-cis-delta2-trans-isomerase   cis,cis-3,6-Dodecadienoyl-CoA <=> trans,cis-Lauro-2,6-dienoyl-CoA","GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005782///peroxisomal matrix","GO:0000062///fatty-acyl-CoA binding+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds+++GO:0003824///catalytic activity+++GO:0005102///signaling receptor binding+++GO:0016853///isomerase activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity","GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0006635///fatty acid beta-oxidation","enoyl-CoA delta isomerase 2","[ECI2_HUMAN|Reviewed]RecName: Full=Enoyl-CoA delta isomerase 2, mitochondrial; EC=5.3.3.8; AltName: Full=DRS-1; AltName: Full=Delta(3),delta(2)-enoyl-CoA isomerase; Short=D3,D2-enoyl-CoA isomerase; AltName: Full=Diazepam-binding inhibitor-related protein 1; Short=DBI-related protein 1; AltName: Full=Dodecenoyl-CoA isomerase; AltName: Full=Hepatocellular carcinoma-associated antigen 88; AltName: Full=Peroxisomal 3,2-trans-enoyl-CoA isomerase; Short=pECI; AltName: Full=Renal carcinoma antigen NY-REN-1; Flags: Precursor;+++[A0A024QZU5_HUMAN|Unreviewed]SubName: Full=Peroxisomal D3,D2-enoyl-CoA isomerase, isoform CRA_a {ECO:0000313|EMBL:EAW55162.1};+++[A0A0C4DGA2_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000420309}; SubName: Full=Testicular secretory protein Li 33 {ECO:0000313|EMBL:AEE61170.1};+++[C9JB63_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417459}; Flags: Fragment;+++[F1LLU7_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417803};+++[F8W6J1_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000369463};+++[F8WAW4_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417170};+++[Q6IBN4_HUMAN|Unreviewed]SubName: Full=PECI protein {ECO:0000313|EMBL:CAG33049.1};"]
[10456,"'HAX1'",646,630,726,667.333333333333,null,"H00100///Neutropenic disorders",null,null,"GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0000932///P-body+++GO:0016529///sarcoplasmic reticulum+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030027///lamellipodium","GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0019966///interleukin-1 binding","GO:0030854///positive regulation of granulocyte differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0042981///regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling","HCLS1 associated protein X-1","[HAX1_HUMAN|Reviewed]RecName: Full=HCLS1-associated protein X-1; AltName: Full=HS1-associating protein X-1; Short=HAX-1; AltName: Full=HS1-binding protein 1; Short=HSP1BP-1;+++[A0A0S2Z519_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 5 {ECO:0000313|EMBL:ALQ33983.1};+++[A0A0S2Z565_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 3 {ECO:0000313|EMBL:ALQ33982.1}; Flags: Fragment;+++[A0A0S2Z591_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 1 {ECO:0000313|EMBL:ALQ33981.1}; Flags: Fragment;+++[E9PIQ7_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000433951};+++[Q5VYD6_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000394920}; Flags: Fragment;"]
[10457,"'GPNMB'",44438,51656,39525,45206.3333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0005887///integral component of plasma membrane","GO:0005178///integrin binding+++GO:0045545///syndecan binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042056///chemoattractant activity+++GO:0048018///receptor ligand activity+++GO:0008201///heparin binding+++GO:0031710///neuromedin B receptor binding","GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0030282///bone mineralization+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0050918///positive chemotaxis+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0050482///arachidonic acid secretion+++GO:0001818///negative regulation of cytokine production+++GO:0045765///regulation of angiogenesis+++GO:0050868///negative regulation of T cell activation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0046888///negative regulation of hormone secretion+++GO:0034103///regulation of tissue remodeling+++GO:0008284///positive regulation of cell proliferation+++GO:0010469///regulation of signaling receptor activity+++GO:0042130///negative regulation of T cell proliferation+++GO:0042593///glucose homeostasis+++GO:0046887///positive regulation of hormone secretion+++GO:0008285///negative regulation of cell proliferation+++GO:0001649///osteoblast differentiation+++GO:0030335///positive regulation of cell migration+++GO:1901215///negative regulation of neuron death+++GO:0007267///cell-cell signaling+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007165///signal transduction","glycoprotein nmb","[GPNMB_HUMAN|Reviewed]RecName: Full=Transmembrane glycoprotein NMB; AltName: Full=Hematopoietic growth factor inducible neurokinin-1 type {ECO:0000303|PubMed:12609765}; Flags: Precursor;+++[A0A024RA55_HUMAN|Unreviewed]SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_b {ECO:0000313|EMBL:EAW93784.1};+++[Q8IXJ5_HUMAN|Unreviewed]SubName: Full=Glycoprotein nmb-like protein {ECO:0000313|EMBL:CAD43718.1};+++[Q96F58_HUMAN|Unreviewed]SubName: Full=GPNMB protein {ECO:0000313|EMBL:AAH11595.1}; SubName: Full=Glycoprotein (Transmembrane) nmb {ECO:0000313|EMBL:AAP35737.1}; SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_a {ECO:0000313|EMBL:EAW93781.1}; SubName: Full=Transmembrane glycoprotein NMB {ECO:0000313|Ensembl:ENSP00000386476};"]
[10458,"'BAIAP2'",2834,2838,2975,2882.33333333333,"04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0099524///postsynaptic cytosol+++GO:0061846///dendritic spine cytoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043197///dendritic spine+++GO:0043025///neuronal cell body+++GO:0097060///synaptic membrane+++GO:0015629///actin cytoskeleton+++GO:0044306///neuron projection terminus+++GO:0042995///cell projection+++GO:0043198///dendritic shaft+++GO:0030175///filopodium+++GO:0001726///ruffle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0098793///presynapse+++GO:0099092///postsynaptic density, intracellular component+++GO:0099523///presynaptic cytosol+++GO:0061845///neuron projection branch point+++GO:0005791///rough endoplasmic reticulum+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0060076///excitatory synapse+++GO:0098794///postsynapse+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0014069///postsynaptic density","GO:0001221///transcription cofactor binding+++GO:0030165///PDZ domain binding+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0070064///proline-rich region binding+++GO:0042802///identical protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0097110///scaffold protein binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding","GO:0010976///positive regulation of neuron projection development+++GO:1905232///cellular response to L-glutamate+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0099564///modification of synaptic structure, modulating synaptic transmission+++GO:0008286///insulin receptor signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0050804///modulation of chemical synaptic transmission+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:0007009///plasma membrane organization+++GO:0007420///brain development+++GO:0030182///neuron differentiation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0016358///dendrite development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0048167///regulation of synaptic plasticity+++GO:0008360///regulation of cell shape+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0051764///actin crosslink formation+++GO:0035418///protein localization to synapse+++GO:0007409///axonogenesis+++GO:0051017///actin filament bundle assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0009617///response to bacterium","BAI1 associated protein 2","[BAIP2_HUMAN|Reviewed]RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2; Short=BAI-associated protein 2; Short=BAI1-associated protein 2; Short=Protein BAP2; AltName: Full=Fas ligand-associated factor 3; Short=FLAF3; AltName: Full=Insulin receptor substrate p53/p58; Short=IRS-58; Short=IRSp53/58; AltName: Full=Insulin receptor substrate protein of 53 kDa; Short=IRSp53; Short=Insulin receptor substrate p53;+++[B4DWA1_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000391837}; SubName: Full=cDNA FLJ55181, highly similar to Brain-specific angiogenesis inhibitor1-associated protein 2 {ECO:0000313|EMBL:BAG62963.1};+++[I3L0M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458202}; Flags: Fragment;+++[I3L0Y9_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458440}; Flags: Fragment;+++[I3L113_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458494}; Flags: Fragment;+++[I3L125_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458522}; Flags: Fragment;+++[I3L1C8_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458735}; Flags: Fragment;+++[I3L2J6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459730};+++[I3L2M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459787}; Flags: Fragment;+++[I3L327_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460131}; Flags: Fragment;+++[I3L3C5_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460344};+++[I3L3C6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460350}; Flags: Fragment;+++[I3L3J7_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460492};+++[I3L4A3_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461101}; Flags: Fragment;+++[I3L4C2_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461144};+++[I3L526_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461736}; Flags: Fragment;"]
[10459,"'MAD2L2'",297,276,374,315.666666666667,"04110///Cell cycle+++05100///Bacterial invasion of epithelial cells+++04114///Oocyte meiosis+++05131///Shigellosis+++04914///Progesterone-mediated oocyte maturation","H00238///Fanconi anemia","M00293///DNA polymerase zeta complex",null,"GO:0005730///nucleolus+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0016035///zeta DNA polymerase complex+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex","GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0008432///JUN kinase binding+++GO:0005515///protein binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0006281///DNA repair+++GO:0042772///DNA damage response, signal transduction resulting in transcription+++GO:0045830///positive regulation of isotype switching+++GO:0006302///double-strand break repair+++GO:0042177///negative regulation of protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0042276///error-prone translesion synthesis+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007015///actin filament organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:0051301///cell division+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining","mitotic arrest deficient 2 like 2","[MD2L2_HUMAN|Reviewed]RecName: Full=Mitotic spindle assembly checkpoint protein MAD2B; AltName: Full=Mitotic arrest deficient 2-like protein 2; Short=MAD2-like protein 2; AltName: Full=REV7 homolog; Short=hREV7;+++[A0A024R4I4_HUMAN|Unreviewed]SubName: Full=MAD2 mitotic arrest deficient-like 2 (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71698.1};+++[B1AK43_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000411807}; Flags: Fragment;+++[B1AK44_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000365857};+++[B1AK45_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000400982}; Flags: Fragment;"]
[10460,"'TACC3'",75,92,109,92,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0072686///mitotic spindle+++GO:0005819///spindle+++GO:0005815///microtubule organizing center+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005515///protein binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization+++GO:1902850///microtubule cytoskeleton organization involved in mitosis+++GO:0060236///regulation of mitotic spindle organization","transforming acidic coiled-coil containing protein 3","[TACC3_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 3; AltName: Full=ERIC-1;+++[C9JA91_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418095}; Flags: Fragment;+++[C9JWI7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000419210}; Flags: Fragment;+++[E7EMT0_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000415914}; Flags: Fragment;+++[F8WC55_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418727};+++[H0Y8F2_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000420838}; Flags: Fragment;+++[Q8IX09_HUMAN|Unreviewed]SubName: Full=Erythropoietin induced cDNA-1 transcript variant 2 {ECO:0000313|EMBL:AAN76993.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000478580};"]
[10461,"'MERTK'",212,185,106,167.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016028///rhabdomere+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0001750///photoreceptor outer segment","GO:0000166///nucleotide binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0017147///Wnt-protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity","GO:0030154///cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0060068///vagina development+++GO:0032940///secretion by cell+++GO:0030168///platelet activation+++GO:0097350///neutrophil clearance+++GO:0001779///natural killer cell differentiation+++GO:2000107///negative regulation of leukocyte apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0050766///positive regulation of phagocytosis+++GO:0050900///leukocyte migration+++GO:0006909///phagocytosis+++GO:0043277///apoptotic cell clearance+++GO:0009968///negative regulation of signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0007267///cell-cell signaling+++GO:0001818///negative regulation of cytokine production+++GO:0007166///cell surface receptor signaling pathway+++GO:0060041///retina development in camera-type eye+++GO:0016055///Wnt signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0016310///phosphorylation+++GO:0051250///negative regulation of lymphocyte activation+++GO:0018108///peptidyl-tyrosine phosphorylation","MER proto-oncogene, tyrosine kinase","[MERTK_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase Mer; EC=2.7.10.1; AltName: Full=Proto-oncogene c-Mer; AltName: Full=Receptor tyrosine kinase MerTK; Flags: Precursor;+++[A0A087WZQ5_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000482824};+++[E9PD22_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000402129};+++[E9PHX8_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000387277};+++[H7C3L9_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000412660}; Flags: Fragment;+++[Q1RMG3_HUMAN|Unreviewed]SubName: Full=MERTK protein {ECO:0000313|EMBL:AAI14919.1};+++[Q53QW0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAX93144.1}; Flags: Fragment;+++[Q53R53_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAY24213.1}; Flags: Fragment;"]
[10463,"'SLC30A9'",736,706,716,719.333333333333,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008324///cation transmembrane transporter activity+++GO:0016922///nuclear receptor binding","GO:0006289///nucleotide-excision repair+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006812///cation transport+++GO:0006811///ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0006829///zinc ion transport","solute carrier family 30 member 9","[ZNT9_HUMAN|Reviewed]RecName: Full=Zinc transporter 9; Short=ZnT-9; AltName: Full=Human embryonic lung protein {ECO:0000303|PubMed:10409434}; Short=HuEL {ECO:0000303|PubMed:10409434}; AltName: Full=Solute carrier family 30 member 9;+++[A0A024R9W8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 (Zinc transporter), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW92999.1};+++[A0A0S2Z512_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 2 {ECO:0000313|EMBL:ALQ33985.1};+++[A0A0S2Z514_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 1 {ECO:0000313|EMBL:ALQ33984.1}; Flags: Fragment;+++[D6R9M6_HUMAN|Unreviewed]SubName: Full=Zinc transporter 9 {ECO:0000313|Ensembl:ENSP00000423529};"]
[10464,"'PIBF1'",148,204,113,155,"03018///RNA degradation+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00530///Joubert syndrome","M00391///Exosome, eukaryotes",null,"GO:0005815///microtubule organizing center+++GO:0034451///centriolar satellite+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005813///centrosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0005136///interleukin-4 receptor binding","GO:0032733///positive regulation of interleukin-10 production+++GO:1905515///non-motile cilium assembly+++GO:0042976///activation of Janus kinase activity+++GO:0071539///protein localization to centrosome+++GO:0090307///mitotic spindle assembly+++GO:0060271///cilium assembly+++GO:0002376///immune system process+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032815///negative regulation of natural killer cell activation+++GO:0031393///negative regulation of prostaglandin biosynthetic process+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0007080///mitotic metaphase plate congression","progesterone immunomodulatory binding factor 1","[PIBF1_HUMAN|Reviewed]RecName: Full=Progesterone-induced-blocking factor 1; Short=PIBF; AltName: Full=Centrosomal protein of 90 kDa; Short=CEP90 {ECO:0000303|PubMed:21224392};+++[A0A087WUI6_HUMAN|Unreviewed]SubName: Full=Progesterone-induced-blocking factor 1 {ECO:0000313|Ensembl:ENSP00000478697};+++[Q05DN0_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH06009.1}; Flags: Fragment;+++[Q4G0R1_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH41806.1};"]
[10465,"'PPIH'",123,130,129,127.333333333333,"03040///Spliceosome",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0071001///U4/U6 snRNP+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0051082///unfolded protein binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0065003///protein-containing complex assembly","peptidylprolyl isomerase H","[PPIH_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase H; Short=PPIase H; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Rotamase H; AltName: Full=Small nuclear ribonucleoprotein particle-specific cyclophilin H; Short=CypH; AltName: Full=U-snRNP-associated cyclophilin SnuCyp-20; Short=USA-CYP;+++[A6NM32_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000361629};+++[C9JAN8_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000405493}; Flags: Fragment;+++[C9JQD4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[H0YEL5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH36_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH57_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[10466,"'COG5'",460,444,432,445.333333333333,"04140///Autophagy - animal+++04910///Insulin signaling pathway+++04137///Mitophagy - animal","H00119///Congenital disorders of glycosylation (CDG) type II",null,null,"GO:0017119///Golgi transport complex+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0032588///trans-Golgi network membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport","component of oligomeric golgi complex 5","[COG5_HUMAN|Reviewed]RecName: Full=Conserved oligomeric Golgi complex subunit 5; Short=COG complex subunit 5; AltName: Full=13S Golgi transport complex 90 kDa subunit; Short=GTC-90; AltName: Full=Component of oligomeric Golgi complex 5; AltName: Full=Golgi transport complex 1;+++[U3KQU7_HUMAN|Unreviewed]SubName: Full=Conserved oligomeric Golgi complex subunit 5 {ECO:0000313|Ensembl:ENSP00000476238}; Flags: Fragment;"]
[10467,"'ZNHIT1'",1276,1359,1681,1438.66666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000812///Swr1 complex","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding","GO:0006338///chromatin remodeling+++GO:0031063///regulation of histone deacetylation+++GO:0043486///histone exchange","zinc finger HIT-type containing 1","[ZNHI1_HUMAN|Reviewed]RecName: Full=Zinc finger HIT domain-containing protein 1; AltName: Full=Cyclin-G1-binding protein 1; AltName: Full=Zinc finger protein subfamily 4A member 1; AltName: Full=p18 Hamlet;"]
[10468,"'FST'",175,220,187,194,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048185///activin binding+++GO:0038102///activin receptor antagonist activity","GO:0051798///positive regulation of hair follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032926///negative regulation of activin receptor signaling pathway","follistatin","[FST_HUMAN|Reviewed]RecName: Full=Follistatin; Short=FS; AltName: Full=Activin-binding protein; Flags: Precursor;+++[A0A024QZU6_HUMAN|Unreviewed]SubName: Full=Follistatin, isoform CRA_c {ECO:0000313|EMBL:EAW54883.1};+++[H0YA75_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426315}; Flags: Fragment;+++[H0YAF9_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426971}; Flags: Fragment;+++[Q6FHE1_HUMAN|Unreviewed]SubName: Full=FST protein {ECO:0000313|EMBL:CAG46612.1};"]
[10469,"'TIMM44'",483,421,503,469,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0051087///chaperone binding","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix","translocase of inner mitochondrial membrane 44","[TIM44_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM44; Flags: Precursor;+++[M0QXM9_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469273}; Flags: Fragment;+++[M0QXU7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469389}; Flags: Fragment;+++[M0R124_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000471596};+++[M0R301_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000472916}; Flags: Fragment;"]
[1047,"'CLGN'",3653,3507,3222,3460.66666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005509///calcium ion binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0007338///single fertilization+++GO:0065003///protein-containing complex assembly+++GO:0007339///binding of sperm to zona pellucida","calmegin","[CLGN_HUMAN|Reviewed]RecName: Full=Calmegin; Flags: Precursor;+++[A0A140VKG2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 79P {ECO:0000313|EMBL:AEE61299.1};"]
[10471,"'PFDN6'",224,208,273,235,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016272///prefoldin complex","GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","prefoldin subunit 6","[PFD6_HUMAN|Reviewed]RecName: Full=Prefoldin subunit 6; AltName: Full=Protein Ke2;+++[A2AB88_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6 {ECO:0000313|Ensembl:ENSP00000420135};+++[I7HJT1_HUMAN|Unreviewed]SubName: Full=HLA class II region expressed gene KE2 {ECO:0000313|EMBL:CAC88187.1}; SubName: Full=Prefoldin subunit 6, isoform CRA_a {ECO:0000313|EMBL:EAX03705.1};+++[Q5STK2_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6, isoform CRA_b {ECO:0000313|EMBL:EAX03706.1}; SubName: Full=cDNA, FLJ92435, Homo sapiens HLA class II region expressed gene KE2 (HKE2), mRNA {ECO:0000313|EMBL:BAG35084.1};"]
[10472,"'ZBTB18'",689,621,413,574.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0000228///nuclear chromosome","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0007275///multicellular organism development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 18","[ZBT18_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 18; AltName: Full=58 kDa repressor protein; AltName: Full=Transcriptional repressor RP58; AltName: Full=Translin-associated zinc finger protein 1; Short=TAZ-1; AltName: Full=Zinc finger protein 238; AltName: Full=Zinc finger protein C2H2-171;+++[A0A024R5T6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 238, isoform CRA_a {ECO:0000313|EMBL:EAW77099.1};"]
[10473,"'HMGN4'",296,326,270,297.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0000785///chromatin","GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding",null,"high mobility group nucleosomal binding domain 4","[HMGN4_HUMAN|Reviewed]RecName: Full=High mobility group nucleosome-binding domain-containing protein 4; AltName: Full=Non-histone chromosomal protein HMG-17-like 3; Short=Non-histone chromosomal protein;+++[A0A024R046_HUMAN|Unreviewed]SubName: Full=High mobility group nucleosomal binding domain 4, isoform CRA_a {ECO:0000313|EMBL:EAW55589.1};"]
[10474,"'TADA3'",2582.36,2772.28,2950.98,2768.54,"05165///Human papillomavirus infection",{"$nulls":3},"GO:0000124///SAGA complex+++GO:0005622///intracellular+++GO:0030914///STAGA complex+++GO:0072686///mitotic spindle+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0033276///transcription factor TFTC complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0016922///nuclear receptor binding+++GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0019904///protein domain specific binding","GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090043///regulation of tubulin deacetylation+++GO:0000278///mitotic cell cycle+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043967///histone H4 acetylation+++GO:0010628///positive regulation of gene expression+++GO:0016579///protein deubiquitination+++GO:0031063///regulation of histone deacetylation+++GO:0001932///regulation of protein phosphorylation+++GO:0031647///regulation of protein stability+++GO:0030520///intracellular estrogen receptor signaling pathway","transcriptional adaptor 3","[TADA3_HUMAN|Reviewed]RecName: Full=Transcriptional adapter 3; AltName: Full=ADA3 homolog; Short=hADA3; AltName: Full=STAF54; AltName: Full=Transcriptional adapter 3-like; Short=ADA3-like protein;+++[A0A024R2D7_HUMAN|Unreviewed]SubName: Full=Transcriptional adaptor 3 (NGG1 homolog, yeast)-like, isoform CRA_a {ECO:0000313|EMBL:EAW63997.1};+++[A8K899_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77724, highly similar to Homo sapiens transcriptional adaptor 3 (NGG1 homolog, yeast)-like (TADA3L), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84953.1};+++[C9JMS0_HUMAN|Unreviewed]SubName: Full=Transcriptional adapter 3 {ECO:0000313|Ensembl:ENSP00000395073}; Flags: Fragment;"]
[10475,"'TRIM38'",427,514,619,520,{"$nulls":4},"GO:0005829///cytosol+++GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050687///negative regulation of defense response to virus+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0046598///positive regulation of viral entry into host cell+++GO:0032648///regulation of interferon-beta production+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0070936///protein K48-linked ubiquitination+++GO:0045087///innate immune response+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","tripartite motif containing 38","[TRI38_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM38; EC=2.3.2.27; AltName: Full=RING finger protein 15; AltName: Full=RING-type E3 ubiquitin transferase TRIM38 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 38; AltName: Full=Zinc finger protein RoRet;+++[A0A024QZY4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 38, isoform CRA_a {ECO:0000313|EMBL:EAW55505.1};"]
[10476,"'ATP5PD'",951,959,1019,976.333333333333,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++05016///Huntington's disease+++05010///Alzheimer's disease+++05012///Parkinson's disease+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0000274///mitochondrial proton-transporting ATP synthase, stator stalk+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005654///nucleoplasm+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005743///mitochondrial inner membrane","GO:0022857///transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0015078///proton transmembrane transporter activity","GO:0015986///ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0006811///ion transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0006754///ATP biosynthetic process+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport","ATP synthase peripheral stalk subunit d","[ATP5H_HUMAN|Reviewed]RecName: Full=ATP synthase subunit d, mitochondrial {ECO:0000305}; Short=ATPase subunit d; AltName: Full=ATP synthase peripheral stalk subunit d {ECO:0000305};+++[A0PJH2_HUMAN|Unreviewed]SubName: Full=ATP5H protein {ECO:0000313|EMBL:AAH29392.1}; Flags: Fragment;+++[F5H608_HUMAN|Unreviewed]SubName: Full=ATP synthase peripheral stalk subunit d {ECO:0000313|Ensembl:ENSP00000437996};+++[L8E9E1_HUMAN|Unreviewed]SubName: Full=Alternative protein ATP5H {ECO:0000313|EMBL:CCQ43351.1};"]
[10477,"'UBE2E3'",749,606,656,670.333333333333,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0070979///protein K11-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0040008///regulation of growth+++GO:0070936///protein K48-linked ubiquitination","ubiquitin conjugating enzyme E2 E3","[UB2E3_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 E3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme E3; AltName: Full=UbcH9; AltName: Full=Ubiquitin carrier protein E3; AltName: Full=Ubiquitin-conjugating enzyme E2-23 kDa; AltName: Full=Ubiquitin-protein ligase E3;+++[A0A1B0GX65_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473525}; Flags: Fragment;+++[R4GMM6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473264};+++[R4GN77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473521}; Flags: Fragment;+++[R4GND1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473591};+++[R4GNG6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473642};"]
[10478,"'SLC25A17'",208,260,231,233,"04146///Peroxisome",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005779///integral component of peroxisomal membrane+++GO:0005778///peroxisomal membrane+++GO:0016021///integral component of membrane+++GO:0005777///peroxisome+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane","GO:0015228///coenzyme A transmembrane transporter activity+++GO:0000295///adenine nucleotide transmembrane transporter activity+++GO:0015230///FAD transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0080122///AMP transmembrane transporter activity+++GO:0005347///ATP transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051087///chaperone binding+++GO:0044610///FMN transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity+++GO:0051724///NAD transmembrane transporter activity","GO:0080121///AMP transport+++GO:0035349///coenzyme A transmembrane transport+++GO:0006635///fatty acid beta-oxidation+++GO:0001561///fatty acid alpha-oxidation+++GO:0015908///fatty acid transport+++GO:0015867///ATP transport+++GO:0015866///ADP transport+++GO:0051182///coenzyme transport+++GO:0035352///NAD transmembrane transport+++GO:0035350///FAD transmembrane transport+++GO:0055085///transmembrane transport+++GO:1901679///nucleotide transmembrane transport","solute carrier family 25 member 17","[PM34_HUMAN|Reviewed]RecName: Full=Peroxisomal membrane protein PMP34; AltName: Full=34 kDa peroxisomal membrane protein; AltName: Full=Solute carrier family 25 member 17;+++[B0QYW5_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000385303};+++[B1AHN4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000404200}; Flags: Fragment;+++[B4DP73_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57410, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG60485.1};+++[B4DU97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57596, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG62259.1};+++[F2Z2I9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000410565};+++[F6RTR7_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000438355};+++[F8WA85_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000263255};+++[F8WBA4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000390502};+++[F8WCH6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000400053};+++[F8WCN9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000416618};+++[F8WE74_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000394539};+++[F8WEC6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000388966};+++[F8WF87_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000407096};"]
[10479,"'SLC9A6'",284,296,249,276.333333333333,null,"H01914///Christianson syndrome",null,null,"GO:0043679///axon terminus+++GO:0030425///dendrite+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0031901///early endosome membrane+++GO:0044308///axonal spine+++GO:0005770///late endosome+++GO:0005789///endoplasmic reticulum membrane","GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity","GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0050808///synapse organization+++GO:0098719///sodium ion import across plasma membrane+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway+++GO:0060996///dendritic spine development+++GO:0048675///axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0051453///regulation of intracellular pH+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0097484///dendrite extension","solute carrier family 9 member A6","[SL9A6_HUMAN|Reviewed]RecName: Full=Sodium/hydrogen exchanger 6; AltName: Full=Na(+)/H(+) exchanger 6; Short=NHE-6; AltName: Full=Solute carrier family 9 member 6;+++[A0A1B0GV11_HUMAN|Unreviewed]RecName: Full=Sodium/hydrogen exchanger {ECO:0000256|RuleBase:RU003722};"]
[1048,"'CEACAM5'",2,0,1,1,{"$nulls":4},"GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0071575///integral component of external side of plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0031225///anchored component of membrane+++GO:0016324///apical plasma membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity+++GO:0034235///GPI anchor binding+++GO:0042802///identical protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034109///homotypic cell-cell adhesion+++GO:0010832///negative regulation of myotube differentiation+++GO:2000811///negative regulation of anoikis+++GO:0050900///leukocyte migration","carcinoembryonic antigen related cell adhesion molecule 5","[CEAM5_HUMAN|Reviewed]RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5; AltName: Full=Carcinoembryonic antigen; Short=CEA; AltName: Full=Meconium antigen 100; AltName: CD_antigen=CD66e; Flags: Precursor;+++[A0A024R0K5_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5, isoform CRA_a {ECO:0000313|EMBL:EAW57060.1};+++[A0A087WYX0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000482157};+++[M0QX98_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000468997}; Flags: Fragment;+++[M0R3J1_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000473252}; Flags: Fragment;+++[Q53G30_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 variant {ECO:0000313|EMBL:BAD96821.1}; Flags: Fragment;+++[Q8N4D0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|EMBL:AAH34671.1};+++[T2HUW8_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 3D {ECO:0000313|EMBL:BAN83790.1};+++[T2HVB7_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 5D {ECO:0000313|EMBL:BAN83789.1};"]
[10480,"'EIF3M'",931,1099,1086,1038.66666666667,{"$nulls":4},"GO:0033290///eukaryotic 48S preinitiation complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0031369///translation initiation factor binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006412///translation+++GO:0006413///translational initiation+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation","eukaryotic translation initiation factor 3 subunit M","[EIF3M_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000255|HAMAP-Rule:MF_03012}; Short=eIF3m {ECO:0000255|HAMAP-Rule:MF_03012}; AltName: Full=Fetal lung protein B5; Short=hFL-B5; AltName: Full=PCI domain-containing protein 1;+++[E7ESM3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435501};+++[E9PN86_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432891}; Flags: Fragment;+++[E9PRI2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432286};+++[E9PRY0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000434080};+++[E9PSB3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435834};+++[H0YCQ8_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432139}; Flags: Fragment;+++[J3KNJ2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000319910}; Flags: Fragment;"]
[10481,"'HOXB13'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008327///methyl-CpG binding","GO:0007275///multicellular organism development+++GO:0008544///epidermis development+++GO:0040008///regulation of growth+++GO:0001525///angiogenesis+++GO:0030850///prostate gland development+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0033574///response to testosterone+++GO:0002009///morphogenesis of an epithelium+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060527///prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis+++GO:0009611///response to wounding","homeobox B13","[HXB13_HUMAN|Reviewed]RecName: Full=Homeobox protein Hox-B13;+++[Q4KR72_HUMAN|Unreviewed]SubName: Full=PSGD protein {ECO:0000313|EMBL:AAY17396.1};+++[V5QRV9_HUMAN|Unreviewed]SubName: Full=Homeobox protein Hox-B13 variant {ECO:0000313|EMBL:AHB20311.1};"]
[10482,"'NXF1'",1185,1223,1241,1216.33333333333,"05168///Herpes simplex infection+++03013///RNA transport+++03015///mRNA surveillance pathway+++05164///Influenza A+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0000346///transcription export complex+++GO:0042405///nuclear inclusion body+++GO:0005737///cytoplasm+++GO:0005643///nuclear pore+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding","GO:0051028///mRNA transport+++GO:0016032///viral process+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus","nuclear RNA export factor 1","[NXF1_HUMAN|Reviewed]RecName: Full=Nuclear RNA export factor 1; AltName: Full=Tip-associated protein; AltName: Full=Tip-associating protein; AltName: Full=mRNA export factor TAP;+++[A0A024R5A9_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW74104.1};+++[B4E227_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61053, highly similar to Nuclear RNA export factor 1 {ECO:0000313|EMBL:BAG64989.1};+++[E9PIN3_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000435742}; Flags: Fragment;+++[E9PLA7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000431381}; Flags: Fragment;+++[E9PMV7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000437296}; Flags: Fragment;+++[E9PQA4_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000432530};+++[H0YDU0_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000434301}; Flags: Fragment;+++[Q59E96_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 variant {ECO:0000313|EMBL:BAD93152.1}; Flags: Fragment;"]
[10483,"'SEC23B'",1131,976,1075,1060.66666666667,"04141///Protein processing in endoplasmic reticulum","H01105///Cranio-lenticulo-sutural dysplasia (CLSD)+++H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)","M00404///COPII complex",null,"GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0012505///endomembrane system+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0008360///regulation of cell shape+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090114///COPII-coated vesicle budding+++GO:0003400///regulation of COPII vesicle coating","Sec23 homolog B, coat complex II component","[SC23B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23B {ECO:0000305}; Short=hSec23B {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein B;+++[A0A2R8Y633_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8Y7S7_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YF30_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YFH5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[Q5QPE1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[Q5QPE2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;"]
[10484,"'SEC23A'",2120,1935,1632,1895.66666666667,"04141///Protein processing in endoplasmic reticulum","H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)+++H01105///Cranio-lenticulo-sutural dysplasia (CLSD)","M00404///COPII complex",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030127///COPII vesicle coat+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0019898///extrinsic component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0070971///endoplasmic reticulum exit site","GO:0005096///GTPase activator activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0090114///COPII-coated vesicle budding+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0015031///protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0003400///regulation of COPII vesicle coating+++GO:0008360///regulation of cell shape+++GO:0007030///Golgi organization+++GO:0006886///intracellular protein transport+++GO:0048208///COPII vesicle coating+++GO:0043547///positive regulation of GTPase activity","Sec23 homolog A, coat complex II component","[SC23A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23A {ECO:0000305}; Short=hSec23A {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein A;+++[F5H365_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V1W4_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V2R6_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V3G5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V4Q2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V4V1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5K1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5X8_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[L8ECD0_HUMAN|Unreviewed]SubName: Full=Alternative protein SEC23A {ECO:0000313|EMBL:CCQ43352.1};"]
[10485,"'C1orf61'",6.11,12,15,11.0366666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003674///molecular_function","GO:0045944///positive regulation of transcription by RNA polymerase II","chromosome 1 open reading frame 61","[CROC4_HUMAN|Reviewed]RecName: Full=Protein CROC-4; AltName: Full=Contingent replication of cDNA 4;+++[H0Y3T1_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000383776}; Flags: Fragment;+++[H3BLW3_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000357225}; Flags: Fragment;+++[Q6PB34_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH59943.1}; Flags: Fragment;+++[Q86W69_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH50448.1}; SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000310651}; Flags: Fragment;+++[X6R5L4_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000350661}; Flags: Fragment;"]
[10486,"'CAP2'",2502,2830,2295,2542.33333333333,"04137///Mitophagy - animal+++03010///Ribosome+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly","M00177///Ribosome, eukaryotes",null,"GO:0005886///plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:1990904///ribonucleoprotein complex","GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008179///adenylate cyclase binding+++GO:0042803///protein homodimerization activity+++GO:0003779///actin binding+++GO:0042802///identical protein binding","GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0007190///activation of adenylate cyclase activity+++GO:0002181///cytoplasmic translation+++GO:0007163///establishment or maintenance of cell polarity+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0006364///rRNA processing+++GO:0008154///actin polymerization or depolymerization+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0007165///signal transduction+++GO:0000902///cell morphogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","cyclase associated actin cytoskeleton regulatory protein 2","[CAP2_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 2; Short=CAP 2;+++[A0A087WZ15_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[A0A087X0J3_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[B7Z385_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[E9PDI2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[F8WDB9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000420615};+++[F8WEW0_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000419906};+++[Q5JPJ8_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};"]
[10487,"'CAP1'",6138,6887,6940,6655,"01100///Metabolic pathways+++04142///Lysosome+++01212///Fatty acid metabolism+++00062///Fatty acid elongation","H00149///Neuronal ceroid lipofuscinosis (NCL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,"R01274///palmitoyl-CoA hydrolase Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid","GO:0035578///azurophil granule lumen+++GO:0030424///axon+++GO:0005764///lysosome+++GO:0030425///dendrite+++GO:0045121///membrane raft+++GO:0005794///Golgi apparatus+++GO:0030864///cortical actin cytoskeleton+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0043025///neuronal cell body+++GO:0043202///lysosomal lumen+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0008179///adenylate cyclase binding+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0003779///actin binding","GO:0030163///protein catabolic process+++GO:0007269///neurotransmitter secretion+++GO:0006898///receptor-mediated endocytosis+++GO:0007042///lysosomal lumen acidification+++GO:0001667///ameboidal-type cell migration+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0008154///actin polymerization or depolymerization+++GO:0007420///brain development+++GO:0030149///sphingolipid catabolic process+++GO:0007601///visual perception+++GO:0007190///activation of adenylate cyclase activity+++GO:0051186///cofactor metabolic process+++GO:0016042///lipid catabolic process+++GO:0046949///fatty-acyl-CoA biosynthetic process+++GO:0043312///neutrophil degranulation+++GO:0051181///cofactor transport+++GO:0050803///regulation of synapse structure or activity+++GO:0002084///protein depalmitoylation+++GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0007268///chemical synaptic transmission+++GO:0006907///pinocytosis+++GO:0050896///response to stimulus+++GO:0048666///neuron development+++GO:0000902///cell morphogenesis+++GO:0007165///signal transduction+++GO:0032429///regulation of phospholipase A2 activity+++GO:0007625///grooming behavior+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048549///positive regulation of pinocytosis+++GO:0044257///cellular protein catabolic process+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0031579///membrane raft organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0030308///negative regulation of cell growth+++GO:0043066///negative regulation of apoptotic process","cyclase associated actin cytoskeleton regulatory protein 1","[CAP1_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 1; Short=CAP 1;+++[D3DPU2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[L8EAI0_HUMAN|Unreviewed]SubName: Full=Alternative protein CAP1 {ECO:0000313|EMBL:CCQ43353.1};+++[Q5T0R1_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413656}; Flags: Fragment;+++[Q5T0R2_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408561}; Flags: Fragment;+++[Q5T0R3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000403198}; Flags: Fragment;+++[Q5T0R4_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413383}; Flags: Fragment;+++[Q5T0R5_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000410586}; Flags: Fragment;+++[Q5T0R6_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000400943}; Flags: Fragment;+++[Q5T0R7_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398475}; Flags: Fragment;+++[Q5T0R8_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000389974}; Flags: Fragment;+++[Q5T0R9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000412859}; Flags: Fragment;+++[Q5T0S3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398877}; Flags: Fragment;"]
[10488,"'CREB3'",1361,1664,1721,1582,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05163///Human cytomegalovirus infection+++04668///TNF signaling pathway+++04714///Thermogenesis+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++04922///Glucagon signaling pathway+++04911///Insulin secretion+++04962///Vasopressin-regulated water reabsorption+++05215///Prostate cancer+++05034///Alcoholism+++05030///Cocaine addiction+++04928///Parathyroid hormone synthesis, secretion and action+++05031///Amphetamine addiction+++04024///cAMP signaling pathway+++04926///Relaxin signaling pathway+++04725///Cholinergic synapse+++04927///Cortisol synthesis and secretion+++05016///Huntington's disease+++05203///Viral carcinogenesis+++04925///Aldosterone synthesis and secretion+++04022///cGMP-PKG signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04211///Longevity regulating pathway+++05165///Human papillomavirus infection+++04934///Cushing's syndrome+++05161///Hepatitis B+++04916///Melanogenesis+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0008140///cAMP response element binding protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:0003682///chromatin binding+++GO:0031726///CCR1 chemokine receptor binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000982///transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0019043///establishment of viral latency+++GO:0001558///regulation of cell growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0051928///positive regulation of calcium ion transport+++GO:0042981///regulation of apoptotic process+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090045///positive regulation of deacetylase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000326///negative regulation of nuclear receptor transcription coactivator activity+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0006990///positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0006351///transcription, DNA-templated+++GO:0019046///release from viral latency+++GO:0016032///viral process+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006935///chemotaxis+++GO:0050930///induction of positive chemotaxis","cAMP responsive element binding protein 3","[CREB3_HUMAN|Reviewed]RecName: Full=Cyclic AMP-responsive element-binding protein 3; Short=CREB-3; Short=cAMP-responsive element-binding protein 3; AltName: Full=Leucine zipper protein; AltName: Full=Luman; AltName: Full=Transcription factor LZIP-alpha; Contains: RecName: Full=Processed cyclic AMP-responsive element-binding protein 3; Short=N-terminal Luman; Short=Transcriptionally active form;"]
[10489,"'LRRC41'",1527,1350,1439,1438.66666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity","GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination","leucine rich repeat containing 41","[LRC41_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 41; AltName: Full=Protein Muf1;+++[A0A087WTI9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000477909}; Flags: Fragment;+++[A0A087WTU1_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000478135};+++[A0A087X0S7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000483633};+++[A0A0B4J2G4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484752};+++[A0A0C4DH00_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484558};+++[Q562F1_HUMAN|Unreviewed]SubName: Full=LRRC41 protein {ECO:0000313|EMBL:AAH92479.1}; Flags: Fragment;"]
[10490,"'VTI1B'",1024,1024,897,981.666666666667,"04138///Autophagy - yeast+++04130///SNARE interactions in vesicular transport","H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00186///Hyperargininemia","M00029///Urea cycle+++M00134///Polyamine biosynthesis, arginine => ornithine => putrescine","R00551///L-Arginine amidinohydrolase L-Arginine + H2O <=> L-Ornithine + Urea","GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031093///platelet alpha granule lumen+++GO:0005829///cytosol+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043025///neuronal cell body+++GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0055037///recycling endosome+++GO:0005764///lysosome+++GO:0031901///early endosome membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0031201///SNARE complex+++GO:0005576///extracellular region+++GO:0008021///synaptic vesicle","GO:0005484///SNAP receptor activity+++GO:0019869///chloride channel inhibitor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0002576///platelet degranulation+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006623///protein targeting to vacuole+++GO:0006896///Golgi to vacuole transport+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0008283///cell proliferation+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0097352///autophagosome maturation","vesicle transport through interaction with t-SNAREs 1B","[VTI1B_HUMAN|Reviewed]RecName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B; AltName: Full=Vesicle transport v-SNARE protein Vti1-like 1; AltName: Full=Vti1-rp1;+++[G3V5I2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000452366};+++[H0YJJ5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451661}; Flags: Fragment;+++[H0YJL5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451759}; Flags: Fragment;+++[J3KMW2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000216456};"]
[104909134,"'LINC02210-CRHR1'",36.2,40,42,39.4,{"$nulls":4},"GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0015056///corticotrophin-releasing factor receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0051458///corticotropin secretion+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:2000852///regulation of corticosterone secretion","LINC02210-CRHR1 readthrough","[CRFR1_HUMAN|Reviewed]RecName: Full=Corticotropin-releasing factor receptor 1; Short=CRF-R-1; Short=CRF-R1; Short=CRFR-1; AltName: Full=Corticotropin-releasing hormone receptor 1; Short=CRH-R-1; Short=CRH-R1; Flags: Precursor;+++[A0A024R9X9_HUMAN|Unreviewed]SubName: Full=Corticotropin releasing hormone receptor 1, isoform CRA_b {ECO:0000313|EMBL:EAW93558.1};+++[B4DMR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60308, highly similar to Corticotropin-releasing factor receptor 1 {ECO:0000313|EMBL:BAG59977.1};"]
[10491,"'CRTAP'",7915,9944,8334,8731,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0050821///protein stabilization+++GO:0007283///spermatogenesis+++GO:0018400///peptidyl-proline hydroxylation to 3-hydroxy-L-proline+++GO:0061077///chaperone-mediated protein folding+++GO:1901874///negative regulation of post-translational protein modification","cartilage associated protein","[CRTAP_HUMAN|Reviewed]RecName: Full=Cartilage-associated protein; Flags: Precursor;+++[B4DPA3_HUMAN|Unreviewed]SubName: Full=Cartilage associated protein, isoform CRA_a {ECO:0000313|EMBL:EAW64448.1}; SubName: Full=cDNA FLJ55123, highly similar to Cartilage-associated protein {ECO:0000313|EMBL:BAG60515.1};+++[C9JP16_HUMAN|Unreviewed]SubName: Full=Cartilage-associated protein {ECO:0000313|Ensembl:ENSP00000409997};"]
[10492,"'SYNCRIP'",1477,1536,1452,1488.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0097452///GAIT complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0070937///CRD-mediated mRNA stability complex+++GO:1990904///ribonucleoprotein complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm","GO:0008143///poly(A) binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0001649///osteoblast differentiation+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0006397///mRNA processing+++GO:0016032///viral process+++GO:0071346///cellular response to interferon-gamma+++GO:0006396///RNA processing+++GO:0000398///mRNA splicing, via spliceosome","synaptotagmin binding cytoplasmic RNA interacting protein","[HNRPQ_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein Q; Short=hnRNP Q; AltName: Full=Glycine- and tyrosine-rich RNA-binding protein; Short=GRY-RBP; AltName: Full=NS1-associated protein 1; AltName: Full=Synaptotagmin-binding, cytoplasmic RNA-interacting protein;+++[B7Z645_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein, isoform CRA_b {ECO:0000313|EMBL:EAW48623.1}; SubName: Full=cDNA FLJ50849, highly similar to Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|EMBL:BAH13131.1};+++[F6UXX1_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|Ensembl:ENSP00000397782}; Flags: Fragment;+++[Q05CK9_HUMAN|Unreviewed]SubName: Full=SYNCRIP protein {ECO:0000313|EMBL:AAH24283.1}; Flags: Fragment;+++[Q59GL1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein variant {ECO:0000313|EMBL:BAD92335.1}; Flags: Fragment;"]
[10493,"'VAT1'",6010,7612,6957,6859.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0035578///azurophil granule lumen+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity","GO:0010637///negative regulation of mitochondrial fusion+++GO:0060337///type I interferon signaling pathway+++GO:0043312///neutrophil degranulation","vesicle amine transport 1","[VAT1_HUMAN|Reviewed]RecName: Full=Synaptic vesicle membrane protein VAT-1 homolog; EC=1.-.-.-;+++[A0A024R1Z6_HUMAN|Unreviewed]SubName: Full=Vesicle amine transport protein 1 homolog (T californica), isoform CRA_a {ECO:0000313|EMBL:EAW60918.1};+++[K7EJM4_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000465239}; Flags: Fragment;+++[K7EM19_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000466322}; Flags: Fragment;+++[K7ENX2_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000467131}; Flags: Fragment;+++[K7ER81_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468146}; Flags: Fragment;+++[K7ERT7_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468401}; Flags: Fragment;+++[K7ESA3_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468621}; Flags: Fragment;"]
[10494,"'STK25'",1892,1978,1995,1955,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding","GO:0023014///signal transduction by protein phosphorylation+++GO:0051683///establishment of Golgi localization+++GO:0006979///response to oxidative stress+++GO:0090168///Golgi reassembly+++GO:0036481///intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0006468///protein phosphorylation+++GO:0050772///positive regulation of axonogenesis+++GO:0046777///protein autophosphorylation+++GO:0016310///phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0007163///establishment or maintenance of cell polarity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051645///Golgi localization","serine/threonine kinase 25","[STK25_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 25; EC=2.7.11.1; AltName: Full=Ste20-like kinase; AltName: Full=Sterile 20/oxidant stress-response kinase 1; Short=SOK-1; Short=Ste20/oxidant stress response kinase 1;+++[A0A024R4B2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71266.1}; SubName: Full=Serine/threonine kinase 25 isoform 1 {ECO:0000313|EMBL:ALQ33986.1};+++[A0A0S2Z4Y2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 3 {ECO:0000313|EMBL:ALQ33988.1}; Flags: Fragment;+++[A0A0S2Z503_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 2 {ECO:0000313|EMBL:ALQ33987.1};+++[B3KRS6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34842 fis, clone NT2NE2011033, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG52488.1};+++[B4DMA5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59346, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG59817.1};+++[B4DVS7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52778, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG62789.1};+++[B4E185_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61527, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG64697.1};+++[C9J232_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000399212}; Flags: Fragment;+++[C9J6L2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000417020}; Flags: Fragment;+++[C9J8E8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000406208}; Flags: Fragment;+++[C9JCC0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403607}; Flags: Fragment;+++[C9JDH9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000395104}; Flags: Fragment;+++[C9JFA1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404552}; Flags: Fragment;+++[C9JIH8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403866}; Flags: Fragment;+++[C9JJV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404960}; Flags: Fragment;+++[C9JN58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000414191}; Flags: Fragment;+++[C9K0M6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000401114}; Flags: Fragment;+++[E7EM58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000412617}; Flags: Fragment;+++[H7C279_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404469}; Flags: Fragment;+++[Q96BA2_HUMAN|Unreviewed]SubName: Full=STK25 protein {ECO:0000313|EMBL:AAH15793.1};"]
[10495,"'ENOX2'",198,187,154,179.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0009897///external side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0016491///oxidoreductase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0005515///protein binding","GO:0048511///rhythmic process+++GO:0007624///ultradian rhythm+++GO:0055114///oxidation-reduction process+++GO:0040008///regulation of growth","ecto-NOX disulfide-thiol exchanger 2","[ENOX2_HUMAN|Reviewed]RecName: Full=Ecto-NOX disulfide-thiol exchanger 2; AltName: Full=APK1 antigen; AltName: Full=Cytosolic ovarian carcinoma antigen 1; AltName: Full=Tumor-associated hydroquinone oxidase; Short=tNOX; Includes: RecName: Full=Hydroquinone [NADH] oxidase; EC=1.-.-.-; Includes: RecName: Full=Protein disulfide-thiol oxidoreductase; EC=1.-.-.-;+++[A0A0C4DGT9_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000478608};+++[A4QPE1_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI39782.2}; Flags: Fragment;+++[B1AKF7_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000400304}; Flags: Fragment;+++[Q32ND0_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI08714.1}; Flags: Fragment;"]
[10497,"'UNC13B'",1205,1146,935,1095.33333333333,"04721///Synaptic vesicle cycle",{"$nulls":3},"GO:0097470///ribbon synapse+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0045202///synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0030672///synaptic vesicle membrane+++GO:0032009///early phagosome+++GO:0048786///presynaptic active zone+++GO:0031594///neuromuscular junction+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098793///presynapse+++GO:0043195///terminal bouton+++GO:0005794///Golgi apparatus+++GO:0044305///calyx of Held+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0017137///Rab GTPase binding+++GO:0030742///GTP-dependent protein binding+++GO:0005516///calmodulin binding+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0006887///exocytosis+++GO:0010808///positive regulation of synaptic vesicle priming+++GO:1900426///positive regulation of defense response to bacterium+++GO:0007268///chemical synaptic transmission+++GO:0050714///positive regulation of protein secretion+++GO:0035556///intracellular signal transduction+++GO:0016081///synaptic vesicle docking+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0061789///dense core granule priming+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0043065///positive regulation of apoptotic process+++GO:0060384///innervation+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:0007528///neuromuscular junction development+++GO:0035249///synaptic transmission, glutamatergic+++GO:0090382///phagosome maturation+++GO:0071333///cellular response to glucose stimulus+++GO:0016079///synaptic vesicle exocytosis+++GO:0031914///negative regulation of synaptic plasticity","unc-13 homolog B","[UN13B_HUMAN|Reviewed]RecName: Full=Protein unc-13 homolog B; AltName: Full=Munc13-2; Short=munc13;+++[A0A0U1RRB5_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489441}; Flags: Fragment;+++[A0A0U1RRL2_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489581};+++[A0A1B0GUS7_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490228};+++[A0A1B0GVW8_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490683};+++[B1AM27_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000380006};+++[F8W8M9_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000367757};+++[I6L9J0_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000484432}; SubName: Full=UNC13B protein {ECO:0000313|EMBL:AAI11801.1};+++[Q4LE73_HUMAN|Unreviewed]SubName: Full=UNC13B variant protein {ECO:0000313|EMBL:BAE06080.1}; Flags: Fragment;"]
[10498,"'CARM1'",1859,1986,1891,1912,"01522///Endocrine resistance",null,null,"R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0042054///histone methyltransferase activity+++GO:0035642///histone methyltransferase activity (H3-R17 specific)+++GO:0042803///protein homodimerization activity+++GO:0070577///lysine-acetylated histone binding+++GO:0008013///beta-catenin binding+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0016274///protein-arginine N-methyltransferase activity","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0016571///histone methylation+++GO:0071168///protein localization to chromatin+++GO:0019216///regulation of lipid metabolic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006479///protein methylation+++GO:0032259///methylation+++GO:0034971///histone H3-R17 methylation+++GO:0060350///endochondral bone morphogenesis+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0016032///viral process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0051591///response to cAMP+++GO:1902415///regulation of mRNA binding+++GO:0034970///histone H3-R2 methylation+++GO:0003420///regulation of growth plate cartilage chondrocyte proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0006325///chromatin organization+++GO:0007568///aging+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:2000171///negative regulation of dendrite development+++GO:0032091///negative regulation of protein binding+++GO:0034969///histone arginine methylation","coactivator associated arginine methyltransferase 1","[CARM1_HUMAN|Reviewed]RecName: Full=Histone-arginine methyltransferase CARM1; EC=2.1.1.319 {ECO:0000269|PubMed:19405910}; AltName: Full=Coactivator-associated arginine methyltransferase 1; AltName: Full=Protein arginine N-methyltransferase 4;+++[K7EIQ8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000464852}; Flags: Fragment;+++[K7EK20_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000465417}; Flags: Fragment;+++[K7EPK1_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467420};+++[K7EQA8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467746}; Flags: Fragment;+++[K7EQB9_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467761}; Flags: Fragment;+++[K7ERM3_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000468319}; Flags: Fragment;"]
[10499,"'NCOA2'",691,609,334,544.666666666667,"04915///Estrogen signaling pathway+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0005102///signaling receptor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0019904///protein domain specific binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0035257///nuclear hormone receptor binding+++GO:0016922///nuclear receptor binding+++GO:0003713///transcription coactivator activity","GO:0048511///rhythmic process+++GO:0032570///response to progesterone+++GO:0015721///bile acid and bile salt transport+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010906///regulation of glucose metabolic process+++GO:0007623///circadian rhythm+++GO:0032870///cellular response to hormone stimulus+++GO:0045475///locomotor rhythm+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0032922///circadian regulation of gene expression+++GO:1904017///cellular response to Thyroglobulin triiodothyronine+++GO:0019216///regulation of lipid metabolic process+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II","nuclear receptor coactivator 2","[NCOA2_HUMAN|Reviewed]RecName: Full=Nuclear receptor coactivator 2; Short=NCoA-2; AltName: Full=Class E basic helix-loop-helix protein 75; Short=bHLHe75; AltName: Full=Transcriptional intermediary factor 2; Short=hTIF2;+++[A0A0B6XJZ8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|EMBL:CEF49517.1}; Flags: Fragment;+++[A0A1D5RMT0_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430850}; Flags: Fragment;+++[B4DPW8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51272, highly similar to Nuclear receptor coactivator 2 {ECO:0000313|EMBL:BAG60730.1};+++[E5RFN9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430348}; Flags: Fragment;+++[E7EWM1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430148};+++[H0YBB6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000429132}; Flags: Fragment;+++[Q569J4_HUMAN|Unreviewed]SubName: Full=NCOA2 protein {ECO:0000313|EMBL:AAH92442.1};"]
[105,"'ADARB2'",2,0,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0004000///adenosine deaminase activity+++GO:0046872///metal ion binding+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0003727///single-stranded RNA binding+++GO:0003725///double-stranded RNA binding","GO:0006382///adenosine to inosine editing+++GO:0006397///mRNA processing+++GO:0006396///RNA processing","adenosine deaminase, RNA specific B2 (inactive)","[RED2_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific editase B2; EC=3.5.-.-; AltName: Full=RNA-dependent adenosine deaminase 3; AltName: Full=RNA-editing deaminase 2; AltName: Full=RNA-editing enzyme 2; AltName: Full=dsRNA adenosine deaminase B2;+++[A4VCH5_HUMAN|Unreviewed]SubName: Full=ADARB2 protein {ECO:0000313|EMBL:AAI39726.1}; Flags: Fragment;+++[Q5VW43_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase B2 {ECO:0000313|Ensembl:ENSP00000370706};+++[Q86X17_HUMAN|Unreviewed]SubName: Full=ADARB2 protein {ECO:0000313|EMBL:AAH47443.1};"]
[1050,"'CEBPA'",22,25,26,24.3333333333333,"05221///Acute myeloid leukemia+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05202///Transcriptional misregulation in cancer+++05200///Pathways in cancer","H00003///Acute myeloid leukemia (AML)",null,null,"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001013///RNA polymerase I regulatory region DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0001892///embryonic placenta development+++GO:0008285///negative regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0030225///macrophage differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006351///transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0030851///granulocyte differentiation+++GO:0050873///brown fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071285///cellular response to lithium ion+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0043032///positive regulation of macrophage activation+++GO:0055088///lipid homeostasis+++GO:0030324///lung development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0045444///fat cell differentiation+++GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000050///urea cycle+++GO:0030099///myeloid cell differentiation+++GO:0008203///cholesterol metabolic process+++GO:0007005///mitochondrion organization+++GO:0048839///inner ear development+++GO:0050872///white fat cell differentiation+++GO:0071407///cellular response to organic cyclic compound+++GO:0048469///cell maturation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006091///generation of precursor metabolites and energy+++GO:0007219///Notch signaling pathway+++GO:0042593///glucose homeostasis+++GO:0006360///transcription by RNA polymerase I","CCAAT enhancer binding protein alpha","[CEBPA_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein alpha {ECO:0000312|HGNC:HGNC:1833}; Short=C/EBP alpha {ECO:0000312|HGNC:HGNC:1833};"]
[10500,"'SEMA6C'",124,145,141,136.666666666667,"04360///Axon guidance",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface","GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0001755///neural crest cell migration+++GO:0030335///positive regulation of cell migration+++GO:0050919///negative chemotaxis+++GO:0007399///nervous system development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0030517///negative regulation of axon extension+++GO:0030154///cell differentiation+++GO:0048843///negative regulation of axon extension involved in axon guidance","semaphorin 6C","[SEM6C_HUMAN|Reviewed]RecName: Full=Semaphorin-6C; AltName: Full=Semaphorin-Y; Short=Sema Y; Flags: Precursor;+++[A0A087WYX3_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000482163};+++[A0A087X0A5_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000483227};+++[Q1RMY5_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14624.1};+++[Q24JR3_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14522.1};"]
[10501,"'SEMA6B'",507,734,496,579,"04360///Axon guidance",{"$nulls":3},"GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0030335///positive regulation of cell migration+++GO:0030154///cell differentiation+++GO:0007399///nervous system development","semaphorin 6B","[SEM6B_HUMAN|Reviewed]RecName: Full=Semaphorin-6B; AltName: Full=Semaphorin-Z; Short=Sema Z; Flags: Precursor;+++[Q9BXR8_HUMAN|Unreviewed]SubName: Full=Semaphorin 6B isoform 2 {ECO:0000313|EMBL:AAK16831.1};"]
[10505,"'SEMA4F'",354.81,362.26,323.83,346.966666666667,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0031290///retinal ganglion cell axon guidance+++GO:0030154///cell differentiation+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0001755///neural crest cell migration+++GO:0007411///axon guidance+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis","ssemaphorin 4F","[SEM4F_HUMAN|Reviewed]RecName: Full=Semaphorin-4F; AltName: Full=Semaphorin-M; Short=Sema M; AltName: Full=Semaphorin-W; Short=Sema W; Flags: Precursor;+++[A0A087WYZ7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000482238};+++[B7Z931_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52836, highly similar to Semaphorin-4F {ECO:0000313|EMBL:BAH14167.1};+++[C9JKW7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000409141}; Flags: Fragment;+++[C9K0A1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000407698}; Flags: Fragment;+++[F8WCP8_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000416490};+++[F8WD61_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000396703};+++[F8WEH3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000413882};"]
[10507,"'SEMA4D'",292.77,320,226.14,279.636666666667,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0004888///transmembrane signaling receptor activity","GO:0008360///regulation of cell shape+++GO:0030335///positive regulation of cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0050919///negative chemotaxis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0050772///positive regulation of axonogenesis+++GO:0007275///multicellular organism development+++GO:0006955///immune response+++GO:0048814///regulation of dendrite morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:1900220///semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis+++GO:0048672///positive regulation of collateral sprouting+++GO:0070486///leukocyte aggregation+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0043931///ossification involved in bone maturation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0007155///cell adhesion+++GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0030154///cell differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007399///nervous system development+++GO:0043547///positive regulation of GTPase activity+++GO:0031344///regulation of cell projection organization+++GO:0045668///negative regulation of osteoblast differentiation","semaphorin 4D","[SEM4D_HUMAN|Reviewed]RecName: Full=Semaphorin-4D; AltName: Full=A8; AltName: Full=BB18; AltName: Full=GR3; AltName: CD_antigen=CD100; Flags: Precursor;+++[A0A0C4DG45_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000399948};+++[C9JD54_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000416747}; Flags: Fragment;+++[C9JFP1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000390754}; Flags: Fragment;+++[C9JYS7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000413352}; Flags: Fragment;+++[E9PFD9_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000395222};+++[F5H044_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000438389}; Flags: Fragment;+++[Q4LE41_HUMAN|Unreviewed]SubName: Full=SEMA4D variant protein {ECO:0000313|EMBL:BAE06112.1}; Flags: Fragment;"]
[10509,"'SEMA4B'",376,363,397,378.666666666667,"04360///Axon guidance","H00527///Retinitis pigmentosa (RP)+++H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0030335///positive regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis+++GO:0030154///cell differentiation+++GO:0071526///semaphorin-plexin signaling pathway","semaphorin 4B","[SEM4B_HUMAN|Reviewed]RecName: Full=Semaphorin-4B; Flags: Precursor;+++[H0YKV7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000452957};+++[H0YLN3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453272}; Flags: Fragment;+++[H0YM68_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453484};+++[H0YMD6_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453563}; Flags: Fragment;+++[H0YMR1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453705}; Flags: Fragment;+++[H0YMZ3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453804}; Flags: Fragment;+++[H0YN49_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453866}; Flags: Fragment;+++[H0YNC4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453951}; Flags: Fragment;+++[H0YNM2_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000454068}; Flags: Fragment;+++[J3KNP4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000332204};+++[Q4VBY2_HUMAN|Unreviewed]SubName: Full=SEMA4B protein {ECO:0000313|EMBL:AAH94849.1}; Flags: Fragment;"]
[1051,"'CEBPB'",1492,1827,1650,1656.33333333333,"05152///Tuberculosis+++04668///TNF signaling pathway+++05202///Transcriptional misregulation in cancer+++04657///IL-17 signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0036488///CHOP-C/EBP complex+++GO:0000779///condensed chromosome, centromeric region+++GO:0000790///nuclear chromatin+++GO:0016363///nuclear matrix+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0035259///glucocorticoid receptor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0042826///histone deacetylase binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0045444///fat cell differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901329///regulation of odontoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0042742///defense response to bacterium+++GO:0045408///regulation of interleukin-6 biosynthetic process+++GO:0035711///T-helper 1 cell activation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0070169///positive regulation of biomineral tissue development+++GO:0032753///positive regulation of interleukin-4 production+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001541///ovarian follicle development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0071347///cellular response to interleukin-1+++GO:0001889///liver development+++GO:0042130///negative regulation of T cell proliferation+++GO:0034976///response to endoplasmic reticulum stress+++GO:2000120///positive regulation of sodium-dependent phosphate transport+++GO:0007613///memory+++GO:0071407///cellular response to organic cyclic compound+++GO:0071230///cellular response to amino acid stimulus+++GO:0001892///embryonic placenta development+++GO:0006366///transcription by RNA polymerase II+++GO:0002432///granuloma formation+++GO:0050873///brown fat cell differentiation+++GO:0097421///liver regeneration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:0045600///positive regulation of fat cell differentiation+++GO:0030182///neuron differentiation+++GO:0072574///hepatocyte proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045670///regulation of osteoclast differentiation+++GO:0030154///cell differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0060850///regulation of transcription involved in cell fate commitment+++GO:2001198///regulation of dendritic cell differentiation","CCAAT enhancer binding protein beta","[CEBPB_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein beta {ECO:0000312|HGNC:HGNC:1834}; Short=C/EBP beta {ECO:0000312|HGNC:HGNC:1834}; AltName: Full=Liver activator protein; Short=LAP; AltName: Full=Liver-enriched inhibitory protein; Short=LIP; AltName: Full=Nuclear factor NF-IL6 {ECO:0000303|PubMed:1741402}; AltName: Full=Transcription factor 5; Short=TCF-5;+++[Q9BSC0_HUMAN|Unreviewed]SubName: Full=CEBPB protein {ECO:0000313|EMBL:AAH05132.2}; Flags: Fragment;+++[W8SNU6_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26745.1}; Flags: Fragment;+++[W8SNV5_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26755.1}; Flags: Fragment;"]
[10512,"'SEMA3C'",4919,5204,4028,4717,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0050919///negative chemotaxis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0003350///pulmonary myocardium development+++GO:0006955///immune response+++GO:0060174///limb bud formation+++GO:0140074///cardiac endothelial to mesenchymal transition+++GO:0001755///neural crest cell migration+++GO:0007507///heart development+++GO:0042493///response to drug+++GO:0030154///cell differentiation+++GO:0009791///post-embryonic development+++GO:0001756///somitogenesis+++GO:0007275///multicellular organism development+++GO:0021915///neural tube development+++GO:0003148///outflow tract septum morphogenesis+++GO:0007399///nervous system development+++GO:0001974///blood vessel remodeling+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0003151///outflow tract morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0007411///axon guidance+++GO:1905312///positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching","semaphorin 3C","[SEM3C_HUMAN|Reviewed]RecName: Full=Semaphorin-3C; AltName: Full=Semaphorin-E; Short=Sema E; Flags: Precursor;+++[F2Z2Y0_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000395398};+++[F8WEP9_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000393825};+++[Q75L25_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS07489.1}; Flags: Fragment;+++[Q75MX0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS00351.1}; Flags: Fragment;"]
[10513,"'APPBP2'",549,584,496,543,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005875///microtubule associated complex+++GO:0005874///microtubule+++GO:0005634///nucleus","GO:0003777///microtubule motor activity+++GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0046907///intracellular transport","amyloid beta precursor protein binding protein 2","[APBP2_HUMAN|Reviewed]RecName: Full=Amyloid protein-binding protein 2; AltName: Full=Amyloid beta precursor protein-binding protein 2; Short=APP-BP2; AltName: Full=Protein interacting with APP tail 1;+++[A0A024QZ47_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW51407.1};+++[K7EIZ9_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000464962}; Flags: Fragment;+++[K7EN61_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000466802};+++[K7ENN3_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000467025};"]
[10514,"'MYBBP1A'",1376,1568,1524,1489.33333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0042564///NLS-dependent protein nuclear import complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0043565///sequence-specific DNA binding+++GO:0070888///E-box binding+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:2000210///positive regulation of anoikis+++GO:0042254///ribosome biogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0001649///osteoblast differentiation+++GO:0071158///positive regulation of cell cycle arrest+++GO:0032922///circadian regulation of gene expression+++GO:0022904///respiratory electron transport chain+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0048511///rhythmic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042149///cellular response to glucose starvation+++GO:0045815///positive regulation of gene expression, epigenetic","MYB binding protein 1a","[MBB1A_HUMAN|Reviewed]RecName: Full=Myb-binding protein 1A;+++[I3L1L3_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000458919}; Flags: Fragment;+++[I3L2H8_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000459692}; Flags: Fragment;+++[I3L311_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000460087}; Flags: Fragment;"]
[10516,"'FBLN5'",8480,10838,9679,9665.66666666667,null,"H00821///Age-related macular degeneration+++H00557///Cutis laxa",null,null,"GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:0031012///extracellular matrix+++GO:0071953///elastic fiber+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0008022///protein C-terminus binding+++GO:0042803///protein homodimerization activity+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0005509///calcium ion binding","GO:2000121///regulation of removal of superoxide radicals+++GO:0048251///elastic fiber assembly+++GO:0030198///extracellular matrix organization+++GO:0034394///protein localization to cell surface+++GO:0007160///cell-matrix adhesion+++GO:0007155///cell adhesion+++GO:0001558///regulation of cell growth+++GO:0046903///secretion","fibulin 5","[FBLN5_HUMAN|Reviewed]RecName: Full=Fibulin-5; Short=FIBL-5; AltName: Full=Developmental arteries and neural crest EGF-like protein; Short=Dance; AltName: Full=Urine p50 protein; Short=UP50; Flags: Precursor;+++[A0A024R6G3_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_b {ECO:0000313|EMBL:EAW81467.1}; SubName: Full=Testis tissue sperm-binding protein Li 75n {ECO:0000313|EMBL:AEE61295.1};+++[G3V2P8_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000450787};+++[G3V329_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451002};+++[G3V3Y2_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451486}; Flags: Fragment;+++[G3V4U0_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451982};+++[G3XA98_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_a {ECO:0000313|EMBL:EAW81465.1}; SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000267620};"]
[10517,"'FBXW10'",0,3.45,1.98,1.81,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0000209///protein polyubiquitination","F-box and WD repeat domain containing 10","[FBW10_HUMAN|Reviewed]RecName: Full=F-box/WD repeat-containing protein 10; AltName: Full=F-box and WD-40 domain-containing protein 10; AltName: Full=Ubiquitin ligase-specificity factor;+++[J3QLH9_HUMAN|Unreviewed]SubName: Full=F-box/WD repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000463552};"]
[10518,"'CIB2'",78,78,91,82.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0042383///sarcolemma+++GO:0005737///cytoplasm+++GO:0032437///cuticular plate+++GO:0005929///cilium+++GO:0005886///plasma membrane+++GO:0005927///muscle tendon junction+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0001750///photoreceptor outer segment+++GO:0016020///membrane+++GO:0072562///blood microparticle+++GO:0032420///stereocilium+++GO:0001917///photoreceptor inner segment","GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0071318///cellular response to ATP+++GO:0055074///calcium ion homeostasis+++GO:0045494///photoreceptor cell maintenance+++GO:0007204///positive regulation of cytosolic calcium ion concentration","calcium and integrin binding family member 2","[CIB2_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding family member 2; AltName: Full=Kinase-interacting protein 2; Short=KIP 2;+++[A0A2R8Y4Y2_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000494155}; Flags: Fragment;+++[H0YKC8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452752};+++[H0YKX8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452980}; Flags: Fragment;+++[H0YLL7_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453256}; Flags: Fragment;+++[H0YLX3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453377}; Flags: Fragment;+++[H0YML3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453654}; Flags: Fragment;+++[H0YND4_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453963};"]
[10519,"'CIB1'",884,997,1046,975.666666666667,"04137///Mitophagy - animal+++04360///Axon guidance+++04140///Autophagy - animal","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016324///apical plasma membrane+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0032433///filopodium tip+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0031982///vesicle+++GO:0030424///axon+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030426///growth cone+++GO:0005815///microtubule organizing center+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0032587///ruffle membrane+++GO:0043025///neuronal cell body+++GO:0071944///cell periphery","GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017016///Ras GTPase binding+++GO:0005509///calcium ion binding+++GO:0044325///ion channel binding+++GO:0043495///protein membrane anchor+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding","GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0071363///cellular response to growth factor stimulus+++GO:0010977///negative regulation of neuron projection development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0007155///cell adhesion+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0042127///regulation of cell proliferation+++GO:0001525///angiogenesis+++GO:0007286///spermatid development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:2000256///positive regulation of male germ cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0001934///positive regulation of protein phosphorylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0051301///cell division+++GO:0030307///positive regulation of cell growth+++GO:0030220///platelet formation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0002931///response to ischemia+++GO:0031122///cytoplasmic microtubule organization+++GO:0008285///negative regulation of cell proliferation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007113///endomitotic cell cycle+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0006302///double-strand break repair+++GO:0007049///cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043085///positive regulation of catalytic activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0051302///regulation of cell division+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0008284///positive regulation of cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006915///apoptotic process+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007283///spermatogenesis","calcium and integrin binding 1","[CIB1_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding protein 1; Short=CIB; AltName: Full=Calcium- and integrin-binding protein; Short=CIBP; AltName: Full=Calmyrin; AltName: Full=DNA-PKcs-interacting protein; AltName: Full=Kinase-interacting protein; Short=KIP; AltName: Full=SNK-interacting protein 2-28; Short=SIP2-28;+++[A0A140VK09_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 9 {ECO:0000313|EMBL:AEE61146.1};"]
[1052,"'CEBPD'",461,275,479,405,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II","CCAAT enhancer binding protein delta","[CEBPD_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein delta; Short=C/EBP delta; AltName: Full=Nuclear factor NF-IL6-beta {ECO:0000303|PubMed:1741402}; Short=NF-IL6-beta {ECO:0000303|PubMed:1741402};+++[Q504X4_HUMAN|Unreviewed]SubName: Full=CEBPD protein {ECO:0000313|EMBL:AAH94715.1};"]
[10520,"'ZNF211'",116,128,137,127,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 211","[ZN211_HUMAN|Reviewed]RecName: Full=Zinc finger protein 211; AltName: Full=Zinc finger protein C2H2-25;+++[A0A0A0MTK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442601};+++[F5GY70_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000440793};+++[F5H771_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442740};+++[H0Y3T8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000384436}; Flags: Fragment;"]
[10521,"'DDX17'",3113,3189,2610,2970.66666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005730///nucleolus","GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008186///RNA-dependent ATPase activity+++GO:0003724///RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding","GO:0045445///myoblast differentiation+++GO:0006396///RNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0010586///miRNA metabolic process+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031047///gene silencing by RNA+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0002376///immune system process+++GO:0030521///androgen receptor signaling pathway+++GO:0001837///epithelial to mesenchymal transition+++GO:0051607///defense response to virus+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006364///rRNA processing+++GO:0006357///regulation of transcription by RNA polymerase II","DEAD-box helicase 17","[DDX17_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX17; EC=3.6.4.13; AltName: Full=DEAD box protein 17; AltName: Full=DEAD box protein p72; AltName: Full=DEAD box protein p82 {ECO:0000303|PubMed:19995069}; AltName: Full=RNA-dependent helicase p72;+++[A0A0U1RQJ0_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000489029}; Flags: Fragment;+++[A0A1W2PQ51_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000491776};+++[A0A1X7SBZ2_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000385536};+++[Q59F66_HUMAN|Unreviewed]SubName: Full=DEAD box polypeptide 17 isoform p82 variant {ECO:0000313|EMBL:BAD92832.1}; Flags: Fragment;"]
[10522,"'DEAF1'",1290,1372,1439,1367,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center+++GO:0005667///transcription factor complex+++GO:0005902///microvillus+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0016605///PML body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0001931///uropod","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding+++GO:0030544///Hsp70 protein binding","GO:0007275///multicellular organism development+++GO:0050900///leukocyte migration+++GO:0009653///anatomical structure morphogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0006935///chemotaxis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050863///regulation of T cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0050901///leukocyte tethering or rolling+++GO:0006955///immune response+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007281///germ cell development+++GO:0001843///neural tube closure+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0006366///transcription by RNA polymerase II+++GO:2000406///positive regulation of T cell migration+++GO:0006968///cellular defense response+++GO:0008542///visual learning+++GO:0042742///defense response to bacterium+++GO:0048706///embryonic skeletal system development+++GO:0007163///establishment or maintenance of cell polarity+++GO:2000404///regulation of T cell migration+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0032609///interferon-gamma production+++GO:0042535///positive regulation of tumor necrosis factor biosynthetic process+++GO:0001662///behavioral fear response","DEAF1 transcription factor","[DEAF1_HUMAN|Reviewed]RecName: Full=Deformed epidermal autoregulatory factor 1 homolog; AltName: Full=Nuclear DEAF-1-related transcriptional regulator; Short=NUDR; AltName: Full=Suppressin; AltName: Full=Zinc finger MYND domain-containing protein 5;+++[A0A0J9YWD6_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000487909}; Flags: Fragment;+++[A0A0J9YX80_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488285}; Flags: Fragment;+++[A0A0J9YXA4_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488313}; Flags: Fragment;+++[C9JUK7_HUMAN|Unreviewed]SubName: Full=Leukosialin {ECO:0000313|Ensembl:ENSP00000412907}; Flags: Fragment;+++[H0YCH1_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000431563}; Flags: Fragment;+++[H0YCY2_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000432518}; Flags: Fragment;"]
[10523,"'CHERP'",1999,2029,1791,1939.66666666667,"03040///Spliceosome",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005623///cell+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0044325///ion channel binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0006874///cellular calcium ion homeostasis+++GO:0007399///nervous system development+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0008285///negative regulation of cell proliferation+++GO:0051209///release of sequestered calcium ion into cytosol","calcium homeostasis endoplasmic reticulum protein","[CHERP_HUMAN|Reviewed]RecName: Full=Calcium homeostasis endoplasmic reticulum protein; AltName: Full=ERPROT 213-21; AltName: Full=SR-related CTD-associated factor 6;+++[J3QK89_HUMAN|Unreviewed]SubName: Full=Calcium homeostasis endoplasmic reticulum protein {ECO:0000313|Ensembl:ENSP00000198939};"]
[10524,"'KAT5'",624,575,645,614.666666666667,"05166///HTLV-I infection","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0000123///histone acetyltransferase complex+++GO:0005730///nucleolus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000790///nuclear chromatin+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0000812///Swr1 complex","GO:0070491///repressing transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0016740///transferase activity+++GO:0042393///histone binding+++GO:0005515///protein binding+++GO:0010485///H4 histone acetyltransferase activity+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0016407///acetyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004402///histone acetyltransferase activity","GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1901985///positive regulation of protein acetylation+++GO:0016032///viral process+++GO:0006302///double-strand break repair+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0000729///DNA double-strand break processing+++GO:0016573///histone acetylation+++GO:0040008///regulation of growth+++GO:0032703///negative regulation of interleukin-2 production+++GO:0010212///response to ionizing radiation+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0071392///cellular response to estradiol stimulus+++GO:0006260///DNA replication+++GO:0030521///androgen receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","lysine acetyltransferase 5","[KAT5_HUMAN|Reviewed]RecName: Full=Histone acetyltransferase KAT5; EC=2.3.1.48 {ECO:0000269|PubMed:10096020, ECO:0000269|PubMed:12468530, ECO:0000269|PubMed:29040603}; AltName: Full=60 kDa Tat-interactive protein; Short=Tip60 {ECO:0000303|PubMed:10096020, ECO:0000303|PubMed:11416127, ECO:0000303|PubMed:12801643, ECO:0000303|PubMed:29040603}; AltName: Full=Histone acetyltransferase HTATIP; Short=HIV-1 Tat interactive protein; AltName: Full=Lysine acetyltransferase 5; AltName: Full=cPLA(2)-interacting protein;+++[A0A024R597_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[A0A024R5E8_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PJI1_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PMG8_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000434993}; Flags: Fragment;+++[E9PRL6_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436012}; Flags: Fragment;+++[E9PRM3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436000}; Flags: Fragment;+++[E9PRS1_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435939}; Flags: Fragment;+++[H0YEG3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435766}; Flags: Fragment;+++[H0YEP0_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436247}; Flags: Fragment;"]
[10525,"'HYOU1'",7456,6928,7200,7194.66666666667,"04141///Protein processing in endoplasmic reticulum","H00118///Congenital disorders of glycosylation (CDG) type I+++H00770///Congenital myasthenic syndrome","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0016020///membrane+++GO:0071682///endocytic vesicle lumen+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005925///focal adhesion","GO:0051087///chaperone binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0036498///IRE1-mediated unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006898///receptor-mediated endocytosis+++GO:0043066///negative regulation of apoptotic process+++GO:1903382///negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway+++GO:0071456///cellular response to hypoxia+++GO:0002931///response to ischemia+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway","hypoxia up-regulated 1","[HYOU1_HUMAN|Reviewed]RecName: Full=Hypoxia up-regulated protein 1; AltName: Full=150 kDa oxygen-regulated protein; Short=ORP-150; AltName: Full=170 kDa glucose-regulated protein; Short=GRP-170; Flags: Precursor;+++[A0A024R3G0_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated 1, isoform CRA_a {ECO:0000313|EMBL:EAW67441.1};+++[A0A087WW13_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000479845}; Flags: Fragment;+++[A0A087WWI4_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000480248};+++[A0A087X054_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000483106};+++[A0A087X214_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000484622}; Flags: Fragment;+++[B3KXH0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45395 fis, clone BRHIP3027191, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAG54482.1};+++[B7Z602_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59408, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13088.1};+++[B7Z766_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54564, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13502.1};+++[E9PJ21_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000431874}; Flags: Fragment;+++[J3KSR2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000464026};+++[J3KTF1_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000462951}; Flags: Fragment;+++[J3QL06_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463318}; Flags: Fragment;+++[J3QLE9_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463515}; Flags: Fragment;+++[J3QQH7_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463742}; Flags: Fragment;+++[K7EQK2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000467866};+++[Q05D91_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH17726.1}; Flags: Fragment;+++[Q6IN67_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH72436.1};+++[Q9BST8_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH04560.1}; SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000482199};"]
[10526,"'IPO8'",524,484,409,472.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005623///cell+++GO:0005635///nuclear envelope","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0060964///regulation of gene silencing by miRNA+++GO:0006886///intracellular protein transport+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction","importin 8","[IPO8_HUMAN|Reviewed]RecName: Full=Importin-8; Short=Imp8; AltName: Full=Ran-binding protein 8; Short=RanBP8;+++[A0A087WXH2_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000481026}; Flags: Fragment;+++[F5GXT5_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000440979}; Flags: Fragment;+++[F5H009_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000444050}; Flags: Fragment;+++[F5H244_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439556}; Flags: Fragment;+++[F5H292_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439413}; Flags: Fragment;+++[F5H2I3_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446254}; Flags: Fragment;+++[F5H815_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000443789};+++[H0YH64_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446232}; Flags: Fragment;"]
[10527,"'IPO7'",1477,1393,1089,1319.66666666667,"04013///MAPK signaling pathway - fly",{"$nulls":3},"GO:0016020///membrane+++GO:0005623///cell+++GO:0005654///nucleoplasm+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005643///nuclear pore","GO:0008536///Ran GTPase binding+++GO:0008565///protein transporter activity+++GO:0042393///histone binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0030695///GTPase regulator activity","GO:0045087///innate immune response+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process","importin 7","[IPO7_HUMAN|Reviewed]RecName: Full=Importin-7; Short=Imp7; AltName: Full=Ran-binding protein 7; Short=RanBP7;+++[B3KNG9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14581 fis, clone NT2RM4001382, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51331.1}; SubName: Full=cDNA FLJ14986 fis, clone Y79AA1000784, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51391.1};+++[E9PLB2_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000435235}; Flags: Fragment;+++[E9PLJ0_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000433313};+++[L8E8A9_HUMAN|Unreviewed]SubName: Full=Alternative protein IPO7 {ECO:0000313|EMBL:CCQ43354.1};"]
[10528,"'NOP56'",789,933,1020,914,"03008///Ribosome biogenesis in eukaryotes","H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0031428///box C/D snoRNP complex+++GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:1990226///histone methyltransferase binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis","NOP56 ribonucleoprotein","[NOP56_HUMAN|Reviewed]RecName: Full=Nucleolar protein 56; AltName: Full=Nucleolar protein 5A;+++[A0PJ92_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH18421.1}; Flags: Fragment;+++[H0Y653_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000403199}; Flags: Fragment;+++[H0YDU4_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000434317}; Flags: Fragment;+++[Q5JXT2_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000388497}; Flags: Fragment;+++[Q9BSN3_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH04937.1};"]
[10529,"'NEBL'",131,81,75,95.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0031005///filamin binding+++GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding+++GO:0008307///structural constituent of muscle+++GO:0005523///tropomyosin binding","GO:0071691///cardiac muscle thin filament assembly","nebulette","[NEBL_HUMAN|Reviewed]RecName: Full=Nebulette; AltName: Full=Actin-binding Z-disk protein;+++[A0A0U1RQY0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489224}; Flags: Fragment;+++[A0A0U1RRI4_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489545}; Flags: Fragment;+++[A0A0U1RRK0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489562}; Flags: Fragment;+++[B0YJ47_HUMAN|Unreviewed]SubName: Full=Nebulette variant 4 {ECO:0000313|EMBL:ACA06025.1};+++[Q2TBD1_HUMAN|Unreviewed]SubName: Full=NEBL protein {ECO:0000313|EMBL:AAI10453.1};+++[Q59FZ8_HUMAN|Unreviewed]SubName: Full=Nebulette non-muscle isoform variant {ECO:0000313|EMBL:BAD92548.1}; Flags: Fragment;+++[Q5JUU7_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000396512}; Flags: Fragment;+++[Q5JUU8_HUMAN|Unreviewed]SubName: Full=Nebulette variant 6 {ECO:0000313|EMBL:ACA06021.1};"]
[1053,"'CEBPE'",0,0,1,0.333333333333333,"05221///Acute myeloid leukemia+++05202///Transcriptional misregulation in cancer","H00101///Other phagocyte defects+++H02024///Neutrophil specific granule deficiency",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding","GO:0071222///cellular response to lipopolysaccharide+++GO:0030851///granulocyte differentiation+++GO:0006952///defense response+++GO:0030225///macrophage differentiation+++GO:0006909///phagocytosis+++GO:0030099///myeloid cell differentiation+++GO:0042089///cytokine biosynthetic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0042742///defense response to bacterium","CCAAT enhancer binding protein epsilon","[CEBPE_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein epsilon; Short=C/EBP epsilon;"]
[10531,"'PITRM1'",2138,1995,1950,2027.66666666667,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008047///enzyme activator activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity","GO:0043085///positive regulation of catalytic activity+++GO:0006508///proteolysis+++GO:0006626///protein targeting to mitochondrion","pitrilysin metallopeptidase 1","[PREP_HUMAN|Reviewed]RecName: Full=Presequence protease, mitochondrial {ECO:0000305|PubMed:16849325}; Short=hPreP {ECO:0000303|PubMed:16849325}; EC=3.4.24.- {ECO:0000269|PubMed:10360838, ECO:0000269|PubMed:16849325, ECO:0000269|PubMed:19196155, ECO:0000269|PubMed:24931469}; AltName: Full=Pitrilysin metalloproteinase 1 {ECO:0000303|PubMed:10360838}; Short=Metalloprotease 1 {ECO:0000303|PubMed:10360838}; Short=hMP1 {ECO:0000303|PubMed:10360838}; Flags: Precursor;+++[A0A0A0MRX9_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000370382};+++[B1APQ0_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000399307}; Flags: Fragment;+++[B1APQ1_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000402072}; Flags: Fragment;+++[H0Y4F7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000391526}; Flags: Fragment;+++[H0Y7L7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000413687}; Flags: Fragment;"]
[10533,"'ATG7'",255,262,261,259.333333333333,"04136///Autophagy - other+++04140///Autophagy - animal+++04138///Autophagy - yeast+++04216///Ferroptosis",{"$nulls":3},"GO:0005930///axoneme+++GO:0034774///secretory granule lumen+++GO:0000407///phagophore assembly site+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0030424///axon+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity+++GO:0019778///Atg12 activating enzyme activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019779///Atg8 activating enzyme activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0004839///ubiquitin activating enzyme activity","GO:0071315///cellular response to morphine+++GO:0006464///cellular protein modification process+++GO:0042752///regulation of circadian rhythm+++GO:0061025///membrane fusion+++GO:0006501///C-terminal protein lipidation+++GO:0016567///protein ubiquitination+++GO:0039521///suppression by virus of host autophagy+++GO:0000422///autophagy of mitochondrion+++GO:0051607///defense response to virus+++GO:0007568///aging+++GO:0031401///positive regulation of protein modification process+++GO:0045732///positive regulation of protein catabolic process+++GO:0060548///negative regulation of cell death+++GO:0043312///neutrophil degranulation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:1902617///response to fluoride+++GO:0090298///negative regulation of mitochondrial DNA replication+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0006995///cellular response to nitrogen starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0010508///positive regulation of autophagy+++GO:0031667///response to nutrient levels+++GO:1901214///regulation of neuron death+++GO:0016236///macroautophagy+++GO:0009749///response to glucose+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0044805///late nucleophagy+++GO:0071455///cellular response to hyperoxia+++GO:0000045///autophagosome assembly+++GO:0009267///cellular response to starvation+++GO:0061684///chaperone-mediated autophagy","autophagy related 7","[ATG7_HUMAN|Reviewed]RecName: Full=Ubiquitin-like modifier-activating enzyme ATG7; AltName: Full=ATG12-activating enzyme E1 ATG7; AltName: Full=Autophagy-related protein 7; Short=APG7-like; Short=hAGP7; AltName: Full=Ubiquitin-activating enzyme E1-like protein;+++[A0A024R2E9_HUMAN|Unreviewed]SubName: Full=ATG7 autophagy related 7 homolog (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW64097.1};+++[B3KQM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90740 fis, clone PLACE1011045, highly similar to Autophagy-related protein 7 {ECO:0000313|EMBL:BAG52088.1};+++[C9J415_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000411880}; Flags: Fragment;+++[C9JE55_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000416644}; Flags: Fragment;+++[C9JFF4_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000415223}; Flags: Fragment;+++[C9JGL2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000390547}; Flags: Fragment;+++[C9JKA3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389996}; Flags: Fragment;+++[C9JNU2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000408303}; Flags: Fragment;+++[F8WDY9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389012};+++[H7BZ92_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000388295}; Flags: Fragment;+++[H7C059_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000393075}; Flags: Fragment;+++[H7C2J8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000406398}; Flags: Fragment;+++[H7C2R3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000407340}; Flags: Fragment;+++[H7C369_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000409844}; Flags: Fragment;"]
[10534,"'SSSCA1'",337,369,394,366.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0030027///lamellipodium","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","Sjogren syndrome/scleroderma autoantigen 1","[SSA27_HUMAN|Reviewed]RecName: Full=Sjoegren syndrome/scleroderma autoantigen 1; AltName: Full=Autoantigen p27;+++[E9PK41_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000431666};+++[E9PN57_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000432938};+++[G3V1B8_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000434381}; SubName: Full=Sjogren's syndrome/scleroderma autoantigen 1, isoform CRA_b {ECO:0000313|EMBL:EAW74407.1};+++[H0YEB6_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435432}; Flags: Fragment;+++[H0YEK1_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435982}; Flags: Fragment;"]
[10535,"'RNASEH2A'",86,85,148,106.333333333333,"03030///DNA replication","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0032299///ribonuclease H2 complex+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin+++GO:0005667///transcription factor complex+++GO:0035976///transcription factor AP-1 complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0004518///nuclease activity+++GO:0004540///ribonuclease activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004519///endonuclease activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042493///response to drug+++GO:0001649///osteoblast differentiation+++GO:0034097///response to cytokine+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006401///RNA catabolic process+++GO:0001570///vasculogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0009987///cellular process+++GO:0010033///response to organic substance+++GO:0016070///RNA metabolic process+++GO:0001701///in utero embryonic development+++GO:0051591///response to cAMP+++GO:0009314///response to radiation+++GO:0043137///DNA replication, removal of RNA primer+++GO:0060136///embryonic process involved in female pregnancy+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032496///response to lipopolysaccharide+++GO:0046697///decidualization+++GO:0060716///labyrinthine layer blood vessel development+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0009612///response to mechanical stimulus+++GO:0006260///DNA replication+++GO:0071277///cellular response to calcium ion+++GO:0006298///mismatch repair+++GO:0001829///trophectodermal cell differentiation+++GO:0033687///osteoblast proliferation+++GO:0045597///positive regulation of cell differentiation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0051726///regulation of cell cycle+++GO:0032870///cellular response to hormone stimulus","ribonuclease H2 subunit A","[RNH2A_HUMAN|Reviewed]RecName: Full=Ribonuclease H2 subunit A; Short=RNase H2 subunit A; EC=3.1.26.4; AltName: Full=Aicardi-Goutieres syndrome 4 protein; Short=AGS4; AltName: Full=RNase H(35); AltName: Full=Ribonuclease HI large subunit; Short=RNase HI large subunit; AltName: Full=Ribonuclease HI subunit A;+++[A0A2R8Y606_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[A0A2R8Y658_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515}; Flags: Fragment;+++[Q6IBG3_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[Q6UQL6_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};"]
[10536,"'P3H3'",2979,3289,3449,3239,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:1902494///catalytic complex","GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0051213///dioxygenase activity+++GO:0019797///procollagen-proline 3-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0031418///L-ascorbic acid binding","GO:0032964///collagen biosynthetic process+++GO:0032963///collagen metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0055114///oxidation-reduction process","prolyl 3-hydroxylase 3","[P3H3_HUMAN|Reviewed]RecName: Full=Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318}; EC=1.14.11.7; AltName: Full=Leprecan-like protein 2 {ECO:0000303|PubMed:15063763}; AltName: Full=Protein B {ECO:0000303|PubMed:8723724}; Flags: Precursor;"]
[105369140,"'LOC105369140'",0,2,1,1,"00380///Tryptophan metabolism+++01100///Metabolic pathways",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin",null,"GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","neuroblastoma breakpoint family member 6-like protein","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369155,"'105369155'",2,3,0,1.66666666666667,{"$nulls":8},"[FBXL2_BOVIN|diamond]RecName: Full=F-box/LRR-repeat protein 2 {ECO:0000305}; AltName: Full=F-box and leucine-rich repeat protein 2 {ECO:0000305};"]
[105369199,"'LOC105369199'",2,1,1,1.33333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0030016///myofibril+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0034622///cellular protein-containing complex assembly+++GO:1903358///regulation of Golgi organization+++GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization","neuroblastoma breakpoint family member 6-like protein","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;"]
[105369201,"'LOC105369201'",51,35,33,39.6666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0042803///protein homodimerization activity",null,"uncharacterized LOC105369201","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369205,"'LOC105369205'",49,63,39,50.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"uncharacterized LOC105369205","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369214,"'LOC105369214'",1,4,0,1.66666666666667,{"$nulls":7},"uncharacterized LOC105369214","[Q9H5V2_HUMAN|Unreviewed]SubName: Full=cDNA: FLJ23003 fis, clone LNG00331 {ECO:0000313|EMBL:BAB15517.1};"]
[105369266,"'LOC105369266'",0,0.25,0,0.0833333333333333,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity","GO:0006468///protein phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:0043405///regulation of MAP kinase activity+++GO:0019933///cAMP-mediated signaling+++GO:0000165///MAPK cascade","uncharacterized LOC105369266","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105369669,"'LOC105369669'",1,0,0,0.333333333333333,"04217///Necroptosis+++05034///Alcoholism+++04137///Mitophagy - animal+++05322///Systemic lupus erythematosus+++04140///Autophagy - animal",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006352///DNA-templated transcription, initiation+++GO:0006342///chromatin silencing+++GO:0006334///nucleosome assembly","uncharacterized LOC105369669","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[H2AJ_BOVIN|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_HUMAN|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_MACFA|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_MOUSE|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H2AJ_RAT|diamond]RecName: Full=Histone H2A.J; Short=H2a/j;+++[H4_HUMAN|diamond]RecName: Full=Histone H4;+++[H4_MACFA|diamond]RecName: Full=Histone H4;+++[H4_PONAB|diamond]RecName: Full=Histone H4;+++[H4_URECA|diamond]RecName: Full=Histone H4;+++[H4_XENTR|diamond]RecName: Full=Histone H4;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369869,"'LOC105369869'",2,0,1,1,{"$nulls":4},"GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0043005///neuron projection+++GO:0098793///presynapse+++GO:0070062///extracellular exosome+++GO:0045211///postsynaptic membrane+++GO:0045202///synapse+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0005923///bicellular tight junction+++GO:0005622///intracellular","GO:0097016///L27 domain binding","GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0048489///synaptic vesicle transport+++GO:0048839///inner ear development+++GO:0007269///neurotransmitter secretion+++GO:1903361///protein localization to basolateral plasma membrane+++GO:0065003///protein-containing complex assembly+++GO:0006887///exocytosis+++GO:0015031///protein transport","uncharacterized LOC105369869","[LIN7A_BOVIN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A;+++[LIN7A_HUMAN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=hLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Tax interaction protein 33; Short=TIP-33; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_MOUSE|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=mLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_RAT|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;"]
[105369914,"'LOC105369914'",2,1,1,1.33333333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","translation initiation factor IF-2-like","[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[PKP2_HUMAN|diamond]RecName: Full=Plakophilin-2;+++[TMCC1_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 1;+++[TMCC2_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 2; AltName: Full=Cerebral protein 11;+++[TMCC2_MOUSE|diamond]RecName: Full=Transmembrane and coiled-coil domains protein 2;+++[TMCC3_HUMAN|diamond]RecName: Full=Transmembrane and coiled-coil domain protein 3;+++[TMCC3_MOUSE|diamond]RecName: Full=Transmembrane and coiled-coil domain protein 3;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[10537,"'UBD'",4,3,5,4,{"$nulls":4},"GO:0016235///aggresome+++GO:0045211///postsynaptic membrane+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0030054///cell junction+++GO:0098793///presynapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0038037///G protein-coupled receptor dimeric complex+++GO:0038039///G protein-coupled receptor heterodimeric complex+++GO:0042734///presynaptic membrane+++GO:0016020///membrane+++GO:0098982///GABA-ergic synapse+++GO:0005737///cytoplasm","GO:0099579///G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential+++GO:0005515///protein binding+++GO:0070628///proteasome binding+++GO:0004965///G protein-coupled GABA receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0006508///proteolysis+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0032446///protein modification by small protein conjugation+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016567///protein ubiquitination+++GO:0034341///response to interferon-gamma+++GO:0043687///post-translational protein modification+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070842///aggresome assembly+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0034612///response to tumor necrosis factor+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","ubiquitin D","[UBD_HUMAN|Reviewed]RecName: Full=Ubiquitin D; AltName: Full=Diubiquitin; AltName: Full=Ubiquitin-like protein FAT10;+++[A0A0G2JH67_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77196.1}; SubName: Full=Ubiquitin D {ECO:0000313|Ensembl:ENSP00000373137};+++[A0A0G2JKF9_HUMAN|Unreviewed]SubName: Full=GABBR1 {ECO:0000313|EMBL:AQY76823.1}; SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000416731};+++[A0A140T9S4_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000412044};+++[A0A140TA42_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000448763};+++[A0A1U9X8S6_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77194.1};+++[C9J342_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417332}; Flags: Fragment;+++[C9JZG6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419755}; Flags: Fragment;+++[F8WAS6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417663};+++[F8WAV2_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417478};+++[F8WDC0_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000420602};+++[F8WF38_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419356};"]
[105370045,"'105370045'",35,54,36,41.6666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding","GO:0061572///actin filament bundle organization+++GO:0061181///regulation of chondrocyte development",null,"[RFLA_HUMAN|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;+++[RFLA_MOUSE|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A {ECO:0000303|PubMed:21709252}; Short=RefilinA;"]
[105370092,"'LOC105370092'",17,7,10,11.3333333333333,{"$nulls":7},"uncharacterized LOC105370092","[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;"]
[105370399,"'LOC105370399'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"uncharacterized LOC105370399","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370579,"'LOC105370579'",2,2,3,2.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC105370579","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370641,"'LOC105370641'",0,2,1,1,{"$nulls":7},"uncharacterized LOC105370641","[A0A146R4I4_FUNHE|diamond]SubName: Full=HCG1778991 {ECO:0000313|EMBL:JAQ63352.1}; Flags: Fragment;+++[A0A287ANQ5_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000045530};+++[A0A287BB99_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000053389};+++[A0A2G8KAB5_STIJA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PIK44956.1};+++[L8IFV1_9CETA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELR54012.1}; Flags: Fragment;"]
[105370687,"'LOC105370687'",34,34,49,39,"03013///RNA transport+++04214///Apoptosis - fly",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0008135///translation factor activity, RNA binding+++GO:0045296///cadherin binding+++GO:0003924///GTPase activity+++GO:0071074///eukaryotic initiation factor eIF2 binding+++GO:0003723///RNA binding+++GO:0005525///GTP binding+++GO:0003743///translation initiation factor activity","GO:0006446///regulation of translational initiation+++GO:0001731///formation of translation preinitiation complex+++GO:0006413///translational initiation+++GO:0090630///activation of GTPase activity","uncharacterized LOC105370687","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[IF5_DROME|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_HUMAN|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_MOUSE|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_PONAB|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_RAT|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370691,"'LOC105370691'",1,1,0,0.666666666666667,{"$nulls":7},"uncharacterized LOC105370691","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[105370705,"'LOC105370705'",1,3,0,1.33333333333333,"03015///mRNA surveillance pathway+++03013///RNA transport+++03040///Spliceosome",null,"M00430///Exon junction complex (EJC)",null,"GO:0061574///ASAP complex+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0019899///enzyme binding+++GO:0003676///nucleic acid binding+++GO:0016887///ATPase activity+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0030218///erythrocyte differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0030263///apoptotic chromosome condensation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0045657///positive regulation of monocyte differentiation+++GO:0006397///mRNA processing","collagen alpha-2(I) chain-like","[ACINU_HUMAN|diamond]RecName: Full=Apoptotic chromatin condensation inducer in the nucleus; Short=Acinus;+++[ACINU_MOUSE|diamond]RecName: Full=Apoptotic chromatin condensation inducer in the nucleus; Short=Acinus;+++[CN119_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf119;+++[CN119_MOUSE|diamond]RecName: Full=Uncharacterized protein C14orf119 homolog;+++[LMLN2_HUMAN|diamond]RecName: Full=Leishmanolysin-like peptidase 2 {ECO:0000305}; EC=3.4.24.- {ECO:0000250|UniProtKB:Q9VH19}; Flags: Precursor;"]
[105370708,"'LOC105370708'",0,3,4,2.33333333333333,{"$nulls":7},"uncharacterized LOC105370708"]
[105370748,"'105370748'",4,1,1,2,{"$nulls":4},"GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0072686///mitotic spindle+++GO:0032580///Golgi cisterna membrane+++GO:0000922///spindle pole+++GO:0000139///Golgi membrane+++GO:0000137///Golgi cis cisterna+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0005794///Golgi apparatus","GO:0045296///cadherin binding+++GO:0019905///syntaxin binding+++GO:0042802///identical protein binding+++GO:0061676///importin-alpha family protein binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding","GO:0051289///protein homotetramerization+++GO:0090307///mitotic spindle assembly+++GO:0007098///centrosome cycle+++GO:0006486///protein glycosylation+++GO:0010507///negative regulation of autophagy+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0008356///asymmetric cell division+++GO:0060050///positive regulation of protein glycosylation+++GO:0032091///negative regulation of protein binding+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0051225///spindle assembly+++GO:0007020///microtubule nucleation+++GO:0048208///COPII vesicle coating+++GO:0090161///Golgi ribbon formation+++GO:0090306///spindle assembly involved in meiosis+++GO:0090166///Golgi disassembly",null,"[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[GOGA2_MOUSE|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein; Short=GM130 {ECO:0000303|PubMed:21552007, ECO:0000303|PubMed:26165940};+++[GOGA2_RAT|diamond]RecName: Full=Golgin subfamily A member 2 {ECO:0000305}; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8557739}; Short=GM130 {ECO:0000303|PubMed:8557739};"]
[105371063,"'LOC105371063'",0,0,0.95,0.316666666666667,{"$nulls":7},"putative uncharacterized protein encoded by LINC00596","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105371095,"'LOC105371095'",0,1,0,0.333333333333333,{"$nulls":7},"collagen alpha-3(IX) chain-like","[PAWR_HUMAN|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_MOUSE|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_RAT|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4; AltName: Full=Transcriptional repressor Par-4-like protein PAWR;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;"]
[105371215,"'LOC105371215'",0,4,0,1.33333333333333,{"$nulls":7},"uncharacterized LOC105371215"]
[105371419,"'LOC105371419'",2,0,1,1,{"$nulls":4},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity",null,"uncharacterized LOC105371419","[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YN010_HUMAN|diamond]RecName: Full=Putative uncharacterized protein PRO2829; Flags: Precursor;"]
[105371566,"'LOC105371566'",2,2,0,1.33333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0016459///myosin complex+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0032420///stereocilium","GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0046872///metal ion binding+++GO:0003774///motor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0005524///ATP binding+++GO:0005516///calmodulin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0042472///inner ear morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007626///locomotory behavior+++GO:0006351///transcription, DNA-templated+++GO:0007605///sensory perception of sound","uncharacterized LOC105371566","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[MYO15_HUMAN|diamond]RecName: Full=Unconventional myosin-XV; AltName: Full=Unconventional myosin-15;+++[PKP2_HUMAN|diamond]RecName: Full=Plakophilin-2;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN429_HUMAN|diamond]RecName: Full=Zinc finger protein 429;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105371763,"'LOC105371763'",15,15,9,13,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0035812///renal sodium excretion+++GO:2001161///negative regulation of histone H3-K79 methylation+++GO:0035811///negative regulation of urine volume+++GO:0010765///positive regulation of sodium ion transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036359///renal potassium excretion","uncharacterized LOC105371763","[AF10_HUMAN|diamond]RecName: Full=Protein AF-10 {ECO:0000305}; AltName: Full=ALL1-fused gene from chromosome 10 protein;+++[AF10_MOUSE|diamond]RecName: Full=Protein AF-10 {ECO:0000305};+++[AF17_HUMAN|diamond]RecName: Full=Protein AF-17; AltName: Full=ALL1-fused gene from chromosome 17 protein;+++[CISD3_HUMAN|diamond]RecName: Full=CDGSH iron-sulfur domain-containing protein 3, mitochondrial; AltName: Full=MitoNEET-related protein 2; Short=Miner2; AltName: Full=Mitochondrial inner NEET protein {ECO:0000303|PubMed:29259115}; Short=MiNT {ECO:0000303|PubMed:29259115}; Flags: Precursor;+++[YM2A_CAEEL|diamond]RecName: Full=Uncharacterized protein F54F2.2, isoform a;"]
[105371910,"'LOC105371910'",19,7,21,15.6666666666667,{"$nulls":4},"GO:0005829///cytosol","GO:0008732///L-allo-threonine aldolase activity","GO:0006545///glycine biosynthetic process+++GO:0006567///threonine catabolic process","uncharacterized LOC105371910","[A0A2U3XS95_LEPWE|diamond]SubName: Full=uncharacterized protein R102.4-like {ECO:0000313|RefSeq:XP_006734331.1};+++[A0A2Y9GBZ0_NEOSC|diamond]SubName: Full=probable low-specificity L-threonine aldolase 2 {ECO:0000313|RefSeq:XP_021536492.1};+++[F7D9Y6_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000005176};+++[G1M5J9_AILME|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSAMEP00000014617};+++[S9XGI9_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY86794.1};"]
[105371932,"'LOC105371932'",10,10,9,9.66666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0005524///ATP binding",null,"uncharacterized LOC105371932","[A0A2K5WEY0_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000035670};+++[A0A2K6C0W4_MACNE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000017314};"]
[105372109,"'LOC105372109'",0,1,1,0.666666666666667,{"$nulls":7},"uncharacterized LOC105372109","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105372269,"'LOC105372269'",1,8,2,3.66666666666667,{"$nulls":4},"GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004856///xylulokinase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004190///aspartic-type endopeptidase activity","GO:0042732///D-xylose metabolic process+++GO:0016032///viral process+++GO:0005997///xylulose metabolic process","endogenous retrovirus group K member 8 Gag polyprotein-like","[EN113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Env polyprotein; AltName: Full=EnvK5 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Env polyprotein; AltName: Full=EnvK3 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C19) envelope protein; AltName: Full=HERV-K_19q11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K_11q22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Env polyprotein; AltName: Full=EnvK2 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C7) envelope protein; AltName: Full=HERV-K(HML-2.HOM) envelope protein; AltName: Full=HERV-K108 envelope protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Env polyprotein; AltName: Full=EnvK6 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K115 envelope protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[GAK21_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 21 Gag polyprotein; AltName: Full=HERV-K_12q14.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[VP113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pro protein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[VPK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pro protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[XYLB_PONAB|diamond]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;"]
[105372315,"'LOC105372315'",9,5,6,6.66666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane",null,null,"endogenous retrovirus group S71 member 1 Env polyprotein","[ENVT1_HUMAN|Reviewed]RecName: Full=Endogenous retrovirus group S71 member 1 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-T Env protein; AltName: Full=HERV-T_19q13.11 provirus ancestral Env polyprotein; Includes: RecName: Full=Surface protein; Short=SU; Includes: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[105372319,"'LOC105372319'",1,1,1,1,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated","zinc finger protein 430-like","[ZN626_HUMAN|diamond]RecName: Full=Zinc finger protein 626;+++[ZN695_HUMAN|diamond]RecName: Full=Zinc finger protein 695; AltName: Full=Zinc finger protein SBZF3;+++[ZN724_HUMAN|diamond]RecName: Full=Zinc finger protein 724 {ECO:0000305};+++[ZN737_HUMAN|diamond]RecName: Full=Zinc finger protein 737; AltName: Full=Zinc finger protein 102;+++[ZNF66_HUMAN|diamond]RecName: Full=Putative zinc finger protein 66; AltName: Full=Zinc finger protein 66 pseudogene;"]
[105372412,"'LOC105372412'",0,1,0,0.333333333333333,{"$nulls":7},"phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein-like","[A0A091DT05_FUKDA|diamond]SubName: Full=Interferon-inducible GTPase 5 {ECO:0000313|EMBL:KFO33613.1};+++[A0A2Y9P5V2_DELLE|diamond]SubName: Full=uncharacterized protein LOC111180525 {ECO:0000313|RefSeq:XP_022440616.1};+++[L9L7Y3_TUPCH|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELW71071.1};+++[M3Y5G8_MUSPF|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMPUP00000006569};+++[Q8WYX9_HUMAN|diamond]SubName: Full=Uncharacterized protein pp10122 {ECO:0000313|EMBL:AAL55824.1};+++[S9YW18_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY88250.1};"]
[105372478,"'LOC105372478'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004930///G protein-coupled receptor activity",null,"taste receptor type 1 member 2-like","[CASR_BOVIN|diamond]RecName: Full=Extracellular calcium-sensing receptor; Short=CaSR; AltName: Full=Parathyroid cell calcium-sensing receptor {ECO:0000303|PubMed:8255296}; Short=BoPCaR1 {ECO:0000303|PubMed:8255296}; Short=PCaR1 {ECO:0000303|PubMed:8255296}; Flags: Precursor;+++[CASR_HUMAN|diamond]RecName: Full=Extracellular calcium-sensing receptor {ECO:0000305}; Short=CaR {ECO:0000303|PubMed:7759551, ECO:0000303|PubMed:8813042}; Short=CaSR; Short=hCasR {ECO:0000303|PubMed:27386547}; AltName: Full=Parathyroid cell calcium-sensing receptor 1 {ECO:0000303|PubMed:8698326}; Short=PCaR1 {ECO:0000303|PubMed:8698326}; Flags: Precursor;+++[CASR_MOUSE|diamond]RecName: Full=Extracellular calcium-sensing receptor; Short=CaSR; AltName: Full=Parathyroid cell calcium-sensing receptor; Short=PCaR1; Flags: Precursor;+++[CASR_PIG|diamond]RecName: Full=Extracellular calcium-sensing receptor; Short=CaSR; AltName: Full=Parathyroid cell calcium-sensing receptor; Short=PCaR1; Flags: Precursor;+++[CASR_RAT|diamond]RecName: Full=Extracellular calcium-sensing receptor; Short=CaSR; AltName: Full=Parathyroid cell calcium-sensing receptor; Short=PCaR1; Short=RaKCaR {ECO:0000303|PubMed:7816802}; Flags: Precursor;"]
[105372704,"'LOC105372704'",0,1,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC105372704"]
[105372824,"'LOC105372824'",16,10,19,15,{"$nulls":7},"uncharacterized LOC105372824","[A0A0B4J2C9_HUMAN|Unreviewed]SubName: Full=Pyridoxal kinase {ECO:0000313|Ensembl:ENSP00000479315};"]
[105372836,"'LOC105372836'",2,2,0,1.33333333333333,{"$nulls":7},"uncharacterized LOC105372836"]
[105372883,"'LOC105372883'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC105372883"]
[105372978,"'LINC01638'",3,3.96,7,4.65333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","long intergenic non-protein coding RNA 1638","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105373057,"'LOC105373057'",0,0,1,0.333333333333333,{"$nulls":7},"DNA-directed RNA polymerase II subunit RPB1-like","[A0A1S3PD37_SALSA|diamond]SubName: Full=uncharacterized protein LOC106584621 isoform X2 {ECO:0000313|RefSeq:XP_014025583.1};+++[A0A1S3PD96_SALSA|diamond]SubName: Full=uncharacterized protein LOC106584621 isoform X1 {ECO:0000313|RefSeq:XP_014025582.1};+++[A0A1U7SCQ5_ALLSI|diamond]SubName: Full=immediate early response 3-interacting protein 1 {ECO:0000313|RefSeq:XP_006038989.1};+++[A0A2A6CG39_PRIPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PDM77048.1}; Flags: Fragment;+++[U3JE66_FICAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000001070};"]
[105373091,"'LOC105373091'",0,1,1,0.666666666666667,{"$nulls":7},"atherin-like"]
[105373102,"'LOC105373102'",22,19,20,20.3333333333333,"05166///HTLV-I infection+++04022///cGMP-PKG signaling pathway+++04020///Calcium signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04218///Cellular senescence+++04217///Necroptosis+++05016///Huntington's disease+++05012///Parkinson's disease","H01118///Progressive external ophthalmoplegia (PEO)+++H00469///Mitochondrial DNA depletion syndrome (MDS)",null,null,"GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane","GO:0008171///O-methyltransferase activity+++GO:0015207///adenine transmembrane transporter activity+++GO:0051213///dioxygenase activity+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0005471///ATP:ADP antiporter activity+++GO:0046872///metal ion binding","GO:0006626///protein targeting to mitochondrion+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0050796///regulation of insulin secretion+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0046732///active induction of host immune response by virus","uncharacterized LOC105373102","[ADT2_BOVIN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_HUMAN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=ADP,ATP carrier protein, fibroblast isoform; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_PONAB|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT3_BOVIN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_HUMAN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_PIG|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ASML_HUMAN|diamond]RecName: Full=N-acetylserotonin O-methyltransferase-like protein; Short=ASMTL; EC=2.1.1.-;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105373132,"'105373132'",1,1,0,0.666666666666667,{"$nulls":8},"[Q96N51_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31401 fis, clone NT2NE2000038 {ECO:0000313|EMBL:BAB71058.1};"]
[105373244,"'LOC105373244'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0030027///lamellipodium","GO:0047394///glycerophosphoinositol inositolphosphodiesterase activity+++GO:0046872///metal ion binding+++GO:0008889///glycerophosphodiester phosphodiesterase activity","GO:0006629///lipid metabolic process+++GO:0090527///actin filament reorganization+++GO:0045669///positive regulation of osteoblast differentiation","uncharacterized LOC105373244","[GDPD2_HUMAN|diamond]RecName: Full=Glycerophosphoinositol inositolphosphodiesterase GDPD2; EC=3.1.4.43; AltName: Full=Glycerophosphodiester phosphodiesterase 3; AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 2; AltName: Full=Osteoblast differentiation promoting factor;+++[GDPD2_MOUSE|diamond]RecName: Full=Glycerophosphoinositol inositolphosphodiesterase GDPD2; EC=3.1.4.43; AltName: Full=Glycerophosphodiester phosphodiesterase 3; AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 2; AltName: Full=Osteoblast differentiation promoting factor;+++[GDPD5_CHICK|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;+++[GDPD5_HUMAN|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;+++[GDPD5_MOUSE|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;"]
[105373289,"'LOC105373289'",5,4,2,3.66666666666667,{"$nulls":7},"collagen alpha-1(III) chain-like"]
[105373311,"'LOC105373311'",108,156,125,129.666666666667,{"$nulls":7},"translation initiation factor IF-2","[A0A1S3WQD2_ERIEU|diamond]SubName: Full=uncharacterized protein LOC107523152 {ECO:0000313|RefSeq:XP_016048578.1};+++[A0A2Y9FXY4_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC101348364 {ECO:0000313|RefSeq:XP_012411968.1};+++[A0A2Y9LSY7_DELLE|diamond]SubName: Full=LOW QUALITY PROTEIN: transcription factor Maf {ECO:0000313|RefSeq:XP_022412460.1};+++[B7Z208_HUMAN|diamond]SubName: Full=cDNA FLJ52622 {ECO:0000313|EMBL:BAH11694.1};"]
[105373314,"'LOC105373314'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005881///cytoplasmic microtubule+++GO:0043209///myelin sheath+++GO:0055037///recycling endosome+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0031594///neuromuscular junction","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton","GO:0007017///microtubule-based process+++GO:0050807///regulation of synapse organization","UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1","[B3GNL_HUMAN|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-; AltName: Full=Beta-1,3-N-acetylglucosaminyltransferase 8; Short=BGnT-8; Short=Beta-1,3-Gn-T8; Short=Beta3Gn-T8;+++[B3GNL_MOUSE|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-;+++[B3GNL_RAT|diamond]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1; Short=BGnT-like protein 1; Short=Beta1,3-N-acetylglucosaminyltransferase-like protein 1; Short=Beta3Gn-T-like protein 1; Short=Beta3GnTL1; EC=2.4.1.-;+++[TBA1A_CRIGR|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 2; AltName: Full=Alpha-tubulin II; AltName: Full=Tubulin alpha-2 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_MOUSE|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Alpha-tubulin isotype M-alpha-1; AltName: Full=Tubulin alpha-1 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_PANTR|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 3; AltName: Full=Tubulin B-alpha-1; AltName: Full=Tubulin alpha-3 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA1A_RAT|diamond]RecName: Full=Tubulin alpha-1A chain; AltName: Full=Alpha-tubulin 1; AltName: Full=Tubulin alpha-1 chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1A chain;+++[TBA_BOMMO|diamond]RecName: Full=Tubulin alpha chain;"]
[105373759,"'LOC105373759'",1.07,3.28,2.01,2.12,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","uncharacterized LOC105373759","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105373780,"'LOC105373780'",9,3,9,7,{"$nulls":7},"proline-rich protein 18-like"]
[105373926,"'105373926'",1,0,1,0.666666666666667,{"$nulls":5},"GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0003676///nucleic acid binding","GO:0015074///DNA integration",null,"[ENR1_HUMAN|diamond]RecName: Full=Endogenous retrovirus group 3 member 1 Env polyprotein; AltName: Full=ERV-3 envelope protein; Short=ERV3 envelope protein; AltName: Full=ERV3-1 envelope protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-R envelope protein; Short=ERV-R envelope protein; AltName: Full=HERV-R_7q21.2 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[PO113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pol protein; AltName: Full=HERV-K113 Pol protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POLY_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon gypsy; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[SYCY2_CALJA|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_MACFA|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PONPY|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[105373944,"'LOC105373944'",5,2,3,3.33333333333333,{"$nulls":7},"translation initiation factor IF-2-like","[A0A2U3ZY91_ODORO|diamond]SubName: Full=collagen alpha-1(I) chain-like {ECO:0000313|RefSeq:XP_012423953.1};"]
[105373989,"'LOC105373989'",23,2,7,10.6666666666667,"04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery","GO:0005125///cytokine activity+++GO:0046789///host cell surface receptor binding+++GO:0005179///hormone activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0042803///protein homodimerization activity+++GO:0008083///growth factor activity","GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0042981///regulation of apoptotic process+++GO:0009267///cellular response to starvation+++GO:0030154///cell differentiation+++GO:0006952///defense response+++GO:0046676///negative regulation of insulin secretion+++GO:0048178///negative regulation of hepatocyte growth factor biosynthetic process+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0032924///activin receptor signaling pathway+++GO:0001541///ovarian follicle development+++GO:0045444///fat cell differentiation+++GO:0009611///response to wounding+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0048468///cell development+++GO:0043408///regulation of MAPK cascade+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0060279///positive regulation of ovulation+++GO:0044320///cellular response to leptin stimulus+++GO:0032869///cellular response to insulin stimulus+++GO:0048599///oocyte development","putative cuticle collagen 91","[INHBB_BOVIN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_HUMAN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_MOUSE|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_PIG|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_RAT|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;"]
[105374013,"'LOC105374013'",26.48,20,4,16.8266666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0042788///polysomal ribosome","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044183///protein binding involved in protein folding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0042803///protein homodimerization activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0005198///structural molecule activity+++GO:0003676///nucleic acid binding","GO:0006915///apoptotic process+++GO:0002181///cytoplasmic translation+++GO:0010458///exit from mitosis+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0006310///DNA recombination+++GO:0016032///viral process+++GO:0021554///optic nerve development+++GO:0007093///mitotic cell cycle checkpoint+++GO:0015074///DNA integration+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0000027///ribosomal large subunit assembly+++GO:0006351///transcription, DNA-templated+++GO:0008616///queuosine biosynthetic process+++GO:0060041///retina development in camera-type eye","endogenous retrovirus group K member 5 Gag polyprotein","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GA113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Gag polyprotein; AltName: Full=HERV-K113 Gag protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Gag polyprotein; AltName: Full=HERV-K101 Gag protein; AltName: Full=HERV-K_22q11.21 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Gag polyprotein; AltName: Full=HERV-K(C7) Gag protein; AltName: Full=HERV-K(HML-2.HOM) Gag protein; AltName: Full=HERV-K108 Gag protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[PDCL3_BOVIN|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_HUMAN|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=HTPHLP; AltName: Full=PhPL3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_MOUSE|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_PONAB|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_RAT|diamond]RecName: Full=Phosducin-like protein 3;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Pol protein; AltName: Full=HERV-K(III) Pol protein; AltName: Full=HERV-K102 Pol protein; AltName: Full=HERV-K_1q22 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[RL24_BOVIN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_FELCA|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_HUMAN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=60S ribosomal protein L30; AltName: Full=Large ribosomal subunit protein eL24 {ECO:0000303|PubMed:24524803};+++[RL24_MACFA|diamond]RecName: Full=60S ribosomal protein L24;+++[RL24_MOUSE|diamond]RecName: Full=60S ribosomal protein L24;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[ZBT11_HUMAN|diamond]RecName: Full=Zinc finger and BTB domain-containing protein 11;"]
[105374089,"'LOC105374089'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0031514///motile cilium+++GO:0097545///axonemal outer doublet","GO:0070840///dynein complex binding","GO:2000574///regulation of microtubule motor activity+++GO:0003341///cilium movement+++GO:0036159///inner dynein arm assembly","uncharacterized LOC105374089","[Q9NXP9_HUMAN|Unreviewed]SubName: Full=HCG1780190 {ECO:0000313|EMBL:EAW79365.1}; SubName: Full=cDNA FLJ20123 fis, clone COL06041 {ECO:0000313|EMBL:BAA90961.1};"]
[105374103,"'LOC105374103'",3,4.83,0,2.61,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity","GO:0015074///DNA integration","uncharacterized LOC105374103","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105374250,"'LINC02054'",0,0,1,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"long intergenic non-protein coding RNA 2054","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[EFMT2_HUMAN|diamond]RecName: Full=EEF1A lysine methyltransferase 2 {ECO:0000255|HAMAP-Rule:MF_03188, ECO:0000312|HGNC:HGNC:33787}; EC=2.1.1.- {ECO:0000255|HAMAP-Rule:MF_03188}; AltName: Full=Methyltransferase-like protein 10 {ECO:0000255|HAMAP-Rule:MF_03188}; AltName: Full=Protein-lysine N-methyltransferase METTL10 {ECO:0000255|HAMAP-Rule:MF_03188};+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105374301,"'LOC105374301'",117,117.09,123.78,119.29,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005813///centrosome+++GO:0030289///protein phosphatase 4 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0019888///protein phosphatase regulator activity+++GO:0030674///protein binding, bridging","GO:0008380///RNA splicing+++GO:0006464///cellular protein modification process+++GO:0006397///mRNA processing+++GO:0010569///regulation of double-strand break repair via homologous recombination","mucin-1-like","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP4R2_CHICK|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_HUMAN|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_MOUSE|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_PONAB|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105374378,"'LOC105374378'",0,0,5,1.66666666666667,"00030///Pentose phosphate pathway+++03010///Ribosome",null,"M00178///Ribosome, bacteria","R02750///2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP+++R01051///ATP:D-ribose 5-phosphotransferase ATP + D-Ribose <=> ADP + D-Ribose 5-phosphate","GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit","GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0003735///structural constituent of ribosome+++GO:0019200///carbohydrate kinase activity+++GO:0004747///ribokinase activity","GO:0019303///D-ribose catabolic process+++GO:0070125///mitochondrial translational elongation+++GO:0046835///carbohydrate phosphorylation+++GO:0070126///mitochondrial translational termination+++GO:0006098///pentose-phosphate shunt","uncharacterized LOC105374378","[RBSK_HUMAN|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000269|PubMed:17585908};+++[RBSK_MOUSE|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000312|EMBL:AAH23339.1}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215};+++[RM33_ANOGA|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_BOVIN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_HUMAN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; AltName: Full=Mitochondrial large ribosomal subunit protein bL33m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[RM33_MOUSE|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_TETNG|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;"]
[105374811,"'LOC105374811'",2,0,0,0.666666666666667,"00230///Purine metabolism+++05166///HTLV-I infection+++00240///Pyrimidine metabolism+++03030///DNA replication+++03420///Nucleotide excision repair+++01100///Metabolic pathways+++03410///Base excision repair",null,"M00263///DNA polymerase epsilon complex","R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dTTP + DNA <=> Diphosphate + DNA+++R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dGTP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dCTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dATP + DNA <=> Diphosphate + DNA","GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0036126///sperm flagellum+++GO:0030425///dendrite+++GO:0061827///sperm head+++GO:0008622///epsilon DNA polymerase complex+++GO:0005886///plasma membrane+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0097225///sperm midpiece+++GO:0005654///nucleoplasm+++GO:0009986///cell surface+++GO:0044297///cell body","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0016496///substance P receptor activity+++GO:0046872///metal ion binding+++GO:0004995///tachykinin receptor activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046982///protein heterodimerization activity","GO:0002687///positive regulation of leukocyte migration+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0045777///positive regulation of blood pressure+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042713///sperm ejaculation+++GO:0007268///chemical synaptic transmission+++GO:0010193///response to ozone+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032197///transposition, RNA-mediated+++GO:0003051///angiotensin-mediated drinking behavior+++GO:0043117///positive regulation of vascular permeability+++GO:0045987///positive regulation of smooth muscle contraction+++GO:1902093///positive regulation of flagellated sperm motility+++GO:0007217///tachykinin receptor signaling pathway+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0045907///positive regulation of vasoconstriction+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0035094///response to nicotine+++GO:0035106///operant conditioning+++GO:0043966///histone H3 acetylation+++GO:0048266///behavioral response to pain+++GO:0045778///positive regulation of ossification+++GO:0009582///detection of abiotic stimulus+++GO:0032570///response to progesterone+++GO:0045471///response to ethanol+++GO:0002118///aggressive behavior+++GO:0046878///positive regulation of saliva secretion+++GO:0046887///positive regulation of hormone secretion+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006954///inflammatory response+++GO:0010996///response to auditory stimulus+++GO:0043278///response to morphine+++GO:0045760///positive regulation of action potential+++GO:0007616///long-term memory+++GO:0051496///positive regulation of stress fiber assembly+++GO:0010634///positive regulation of epithelial cell migration+++GO:0009408///response to heat+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0051602///response to electrical stimulus+++GO:0019233///sensory perception of pain+++GO:0008306///associative learning+++GO:0002526///acute inflammatory response+++GO:0006310///DNA recombination+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042755///eating behavior+++GO:0032355///response to estradiol+++GO:0014910///regulation of smooth muscle cell migration","uncharacterized LOC105374811","[DPOE4_BOVIN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4;+++[DPOE4_HUMAN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[DPOE4_MOUSE|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NFYC_BOVIN|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NFYC_RAT|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=CCAAT-binding transcription factor subunit C; Short=CBF-C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NK1R_CANLF|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_CAVPO|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_HUMAN|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_MOUSE|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_RAT|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;"]
[105375106,"'LOC105375106'",0,3,1,1.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030027///lamellipodium",null,"GO:0030335///positive regulation of cell migration+++GO:2000813///negative regulation of barbed-end actin filament capping+++GO:0051638///barbed-end actin filament uncapping+++GO:1902745///positive regulation of lamellipodium organization","uncharacterized LOC105375106","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[105375355,"'UPK3B'",27784,32872,39867,33507.6666666667,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++04330///Notch signaling pathway","H01439///Williams-Beuren syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0010629///negative regulation of gene expression","uroplakin 3B","[UPK3B_HUMAN|Reviewed]RecName: Full=Uroplakin-3b; Short=UP3b; AltName: Full=Uroplakin IIIb; Short=UPIIIb; AltName: Full=p35; Flags: Precursor;+++[A0A0J9YVS6_HUMAN|Unreviewed]SubName: Full=Uroplakin-3b {ECO:0000313|Ensembl:ENSP00000487650};"]
[105375975,"'LOC105375975'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005751///mitochondrial respiratory chain complex IV+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0005730///nucleolus+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0044547///DNA topoisomerase binding+++GO:0003697///single-stranded DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0046975///histone methyltransferase activity (H3-K36 specific)+++GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0004129///cytochrome-c oxidase activity+++GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0004519///endonuclease activity","GO:0071157///negative regulation of cell cycle arrest+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0008283///cell proliferation+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0000729///DNA double-strand break processing+++GO:2000373///positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity+++GO:1902600///proton transmembrane transport+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining+++GO:0044774///mitotic DNA integrity checkpoint+++GO:0031297///replication fork processing+++GO:0015074///DNA integration+++GO:0010452///histone H3-K36 methylation+++GO:0051568///histone H3-K4 methylation+++GO:0097676///histone H3-K36 dimethylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:2001251///negative regulation of chromosome organization","histone-lysine N-methyltransferase SETMAR-like","[COX8C_HUMAN|diamond]RecName: Full=Cytochrome c oxidase subunit 8C, mitochondrial; AltName: Full=Cytochrome c oxidase polypeptide 8 isoform 3; AltName: Full=Cytochrome c oxidase polypeptide VIII isoform 3; Short=COX VIII-3; AltName: Full=Cytochrome c oxidase subunit 8-3; Short=COX8-3; AltName: Full=Cytochrome c oxidase subunit VIIIC; Flags: Precursor;+++[MOS1T_DROMA|diamond]RecName: Full=Mariner Mos1 transposase; EC=3.1.-.-; AltName: Full=Transposable element Mos1 transposase;+++[SETMR_HUMAN|diamond]RecName: Full=Histone-lysine N-methyltransferase SETMAR {ECO:0000305}; AltName: Full=SET domain and mariner transposase fusion protein {ECO:0000305}; Short=Metnase {ECO:0000303|PubMed:16332963}; Includes: RecName: Full=Histone-lysine N-methyltransferase {ECO:0000305}; EC=2.1.1.43 {ECO:0000269|PubMed:16332963}; Includes: RecName: Full=Transposon Hsmar1 transposase {ECO:0000303|PubMed:9461395}; EC=3.1.-.- {ECO:0000269|PubMed:16332963};"]
[105376204,"'LOC105376204'",8,9,10,9,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"uncharacterized LOC105376204","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376341,"'LOC105376341'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC105376341","[PK1L3_MOUSE|diamond]RecName: Full=Polycystic kidney disease protein 1-like 3; AltName: Full=PC1-like 3 protein; AltName: Full=Polycystin-1L3; Flags: Precursor;"]
[105376353,"'LOC105376353'",40,20,27,29,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity",null,"mucin-5AC-like","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FTM_HUMAN|diamond]RecName: Full=Protein fantom; AltName: Full=Nephrocystin-8; AltName: Full=RPGR-interacting protein 1-like protein; Short=RPGRIP1-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105376525,"'LOC105376525'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003824///catalytic activity","GO:0008152///metabolic process","ectonucleotide pyrophosphatase/phosphodiesterase family member 7-like","[ENPP7_HUMAN|diamond]RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; Short=E-NPP 7; Short=NPP-7; EC=3.1.4.12 {ECO:0000269|PubMed:12671034, ECO:0000269|PubMed:12885774, ECO:0000269|PubMed:15205117, ECO:0000269|PubMed:28292932}; AltName: Full=Alkaline sphingomyelin phosphodiesterase; AltName: Full=Intestinal alkaline sphingomyelinase {ECO:0000303|PubMed:12671034, ECO:0000303|PubMed:12885774}; Short=Alk-SMase {ECO:0000303|PubMed:12885774, ECO:0000303|PubMed:28292932}; Flags: Precursor;+++[ENPP7_RAT|diamond]RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 7; Short=E-NPP 7; Short=NPP-7; EC=3.1.4.12 {ECO:0000269|PubMed:15708357}; AltName: Full=Alkaline sphingomyelin phosphodiesterase; AltName: Full=Intestinal alkaline sphingomyelinase; Short=Alk-SMase; Flags: Precursor;"]
[105376526,"'LOC105376526'",2.91,4,0,2.30333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0016021///integral component of membrane","GO:0003723///RNA binding","GO:0051028///mRNA transport","uncharacterized LOC105376526","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[ENR1_HUMAN|diamond]RecName: Full=Endogenous retrovirus group 3 member 1 Env polyprotein; AltName: Full=ERV-3 envelope protein; Short=ERV3 envelope protein; AltName: Full=ERV3-1 envelope protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-R envelope protein; Short=ERV-R envelope protein; AltName: Full=HERV-R_7q21.2 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ERK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Rec protein; AltName: Full=Endogenous retrovirus group K member 25; AltName: Full=HERV-K_11q22.1 provirus Rec protein;+++[POL1_MOUSE|diamond]RecName: Full=Retrovirus-related Pol polyprotein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; Flags: Fragment;+++[REC19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Rec protein; AltName: Full=HERV-K(C19) Rec protein; AltName: Full=HERV-K_19q11 provirus Rec protein;+++[REC6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Rec protein; AltName: Full=Central open reading frame; Short=c-orf; Short=cORF; AltName: Full=Endogenous retrovirus K protein 6; AltName: Full=HERV-K(C7) Rec protein; AltName: Full=HERV-K(HML-2.HOM) Rec protein; AltName: Full=HERV-K108 Rec protein; AltName: Full=HERV-K_7p22.1 provirus Rec protein; AltName: Full=K-Rev; AltName: Full=Rev-like protein; AltName: Full=Rev/Rex homolog;+++[REC9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Rec protein; AltName: Full=HERV-K(C6) Rec protein; AltName: Full=HERV-K109 Rec protein; AltName: Full=HERV-K_6q14.1 provirus Rec protein;+++[RECK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Rec protein; AltName: Full=HERV-K115 Rec protein; AltName: Full=HERV-K_8p23.1 provirus Rec protein;+++[SYCY2_CALJA|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PANTR|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PONPY|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ZMAT1_HUMAN|diamond]RecName: Full=Zinc finger matrin-type protein 1;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105376684,"'LOC105376684'",5.32,13,4.34,7.55333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"translation initiation factor IF-2-like","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376722,"'LOC105376722'",1,1,0,0.666666666666667,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"uncharacterized LOC105376722","[GG6L3_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 6-like protein 3;+++[GG6L4_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 4;+++[GG6L9_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 9 {ECO:0000305};+++[GG6LA_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000305};+++[GG6LS_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 6-like protein 19;+++[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;"]
[105376875,"'LOC105376875'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC105376875"]
[105376906,"'LOC105376906'",22,19.42,10.43,17.2833333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0015074///DNA integration","endogenous retrovirus group K member 19 Pol protein","[PO113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pol protein; AltName: Full=HERV-K113 Pol protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Pol protein; AltName: Full=HERV-K(C19) Pol protein; AltName: Full=HERV-K_19q11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;"]
[105376917,"'LOC105376917'",4,1,1,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0031093///platelet alpha granule lumen+++GO:0005576///extracellular region","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0008134///transcription factor binding","GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated+++GO:0002576///platelet degranulation+++GO:0048599///oocyte development","uncharacterized LOC105376917","[CE017_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C5orf17;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FIGLA_HUMAN|diamond]RecName: Full=Factor in the germline alpha; Short=FIGalpha; AltName: Full=Class C basic helix-loop-helix protein 8; Short=bHLHc8; AltName: Full=Folliculogenesis-specific basic helix-loop-helix protein; AltName: Full=Transcription factor FIGa;+++[FIGLA_MOUSE|diamond]RecName: Full=Factor in the germline alpha; Short=FIGalpha; AltName: Full=Transcription factor FIGa;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NR3L1_HUMAN|diamond]RecName: Full=Natural cytotoxicity triggering receptor 3 ligand 1; AltName: Full=B7 homolog 6; Short=B7-H6; Flags: Precursor;+++[NR3L1_PONAB|diamond]RecName: Full=Natural cytotoxicity triggering receptor 3 ligand 1; AltName: Full=B7 homolog 6; Short=B7-H6; Flags: Precursor;+++[TX264_HUMAN|diamond]RecName: Full=Testis-expressed protein 264; AltName: Full=Putative secreted protein Zsig11; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN431_HUMAN|diamond]RecName: Full=Zinc finger protein 431;+++[ZN492_HUMAN|diamond]RecName: Full=Zinc finger protein 492; AltName: Full=Zinc finger protein 115;+++[ZN730_HUMAN|diamond]RecName: Full=Putative zinc finger protein 730;+++[ZNF85_HUMAN|diamond]RecName: Full=Zinc finger protein 85; AltName: Full=Zinc finger protein HPF4; AltName: Full=Zinc finger protein HTF1;+++[ZNF98_HUMAN|diamond]RecName: Full=Zinc finger protein 98; AltName: Full=Zinc finger protein 739; AltName: Full=Zinc finger protein F7175;"]
[105377022,"'LOC105377022'",3,4,5,4,{"$nulls":7},"uncharacterized LOC105377022"]
[105377310,"'LOC105377310'",2,0,1,1,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane",null,"GO:0006949///syncytium formation","syncytin-1-like","[SYCY1_GORGO|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY1_HUMAN|diamond]RecName: Full=Syncytin-1; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Env-W; AltName: Full=Envelope polyprotein gPr73; AltName: Full=Enverin; AltName: Full=HERV-7q Envelope protein; AltName: Full=HERV-W envelope protein; AltName: Full=HERV-W_7q21.2 provirus ancestral Env polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; AltName: Full=gp50; Contains: RecName: Full=Transmembrane protein; Short=TM; AltName: Full=gp24; Flags: Precursor;+++[SYCY1_HYLPI|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY1_PANTR|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY1_PONPY|diamond]RecName: Full=Syncytin-1; AltName: Full=ERV-W1 provirus ancestral Env polyprotein; AltName: Full=ERVWE1 envelope protein; AltName: Full=Endogenous retrovirus group W member 1; AltName: Full=Envelope polyprotein; AltName: Full=Syncytin; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[105377622,"'LOC105377622'",13,12,7,10.6666666666667,{"$nulls":7},"uncharacterized LOC105377622","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105377650,"'LOC105377650'",10,5,15,10,{"$nulls":7},"uncharacterized LOC105377650","[A0A1B0GRK0_MOUSE|diamond]SubName: Full=Predicted gene 45521 {ECO:0000313|Ensembl:ENSMUSP00000147554};+++[A0A2I2UDG9_FELCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000030524};+++[G3HFM3_CRIGR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGV92989.1};+++[L5K8U9_PTEAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELK07797.1};+++[S9WRC2_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY81017.1};"]
[105377777,"'LOC105377777'",1,0,1,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"uncharacterized LOC105377777","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105377805,"'LOC105377805'",8,3,4,5,{"$nulls":7},"basic salivary proline-rich protein 4-like","[A0A026VVN5_OOCBI|diamond]SubName: Full=F-box only protein {ECO:0000313|EMBL:EZA47853.1};+++[A0A060YYP9_ONCMY|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDQ96866.1}; Flags: Fragment;+++[A0A093I0R1_STRCA|diamond]SubName: Full=Putative proline-rich protein 21 {ECO:0000313|EMBL:KFV87521.1}; Flags: Fragment;+++[A0A099ZME2_TINGU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGL82088.1}; Flags: Fragment;+++[A0A2T7NET3_POMCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PVD19655.1};"]
[105378592,"'105378592'",1,1,0,0.666666666666667]
[105378862,"'LOC105378862'",59,102,83,81.3333333333333,{"$nulls":7},"translation initiation factor IF-2-like","[F6VET6_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000009862};+++[F7DFZ3_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000012093};+++[F7DXK1_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000017383};"]
[105378947,"'LOC105378947'",0,0,1,0.333333333333333,{"$nulls":7},"proline-rich extensin-like protein EPR1","[E2BKF3_HARSA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EFN83838.1};"]
[105378949,"'LOC105378949'",8,12,8,9.33333333333333,{"$nulls":7},"collagen alpha-2(VIII) chain"]
[105379045,"'105379045'",4,3,2,3,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":7},"[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379177,"'LOC105379177'",4,1.08,1,2.02666666666667,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"uncharacterized LOC105379177","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379198,"'LOC105379198'",2,1,4,2.33333333333333,{"$nulls":5},"GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination","uncharacterized LOC105379198","[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[105379282,"'LOC105379282'",0,0,3,1,{"$nulls":7},"glucose-dependent insulinotropic receptor-like","[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;"]
[105379356,"'LOC105379356'",0,4,1,1.66666666666667,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity",null,"uncharacterized LOC105379356","[A0A087X0J2_HUMAN|diamond]SubName: Full=UBX domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000483433}; Flags: Fragment;+++[A0A2U3ZSI3_ODORO|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC105758093 {ECO:0000313|RefSeq:XP_012421949.1};+++[Q1KYL9_MOUSE|diamond]SubName: Full=Gag-pro-pol polyprotein {ECO:0000313|EMBL:ABD14436.1}; Flags: Precursor;+++[Q1KYM2_MOUSE|diamond]SubName: Full=Gag-pro-pol polyprotein {ECO:0000313|EMBL:ABD14433.1}; Flags: Precursor;+++[Q86UH8_HUMAN|diamond]SubName: Full=Pol protein {ECO:0000313|EMBL:AAP29639.1};"]
[105379443,"'LOC105379443'",53.78,52.03,21.59,42.4666666666667,"04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal+++00670///One carbon pool by folate",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0016805///dipeptidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005524///ATP binding+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0008236///serine-type peptidase activity+++GO:0043565///sequence-specific DNA binding+++GO:0050129///N-formylglutamate deformylase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0004329///formate-tetrahydrofolate ligase activity","GO:0015942///formate metabolic process+++GO:0042135///neurotransmitter catabolic process+++GO:0046655///folic acid metabolic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0035999///tetrahydrofolate interconversion+++GO:0006760///folic acid-containing compound metabolic process+++GO:0001843///neural tube closure+++GO:0006351///transcription, DNA-templated+++GO:0009257///10-formyltetrahydrofolate biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0006310///DNA recombination+++GO:0006508///proteolysis+++GO:0048703///embryonic viscerocranium morphogenesis","monofunctional C1-tetrahydrofolate synthase, mitochondrial-like","[BEND2_HUMAN|diamond]RecName: Full=BEN domain-containing protein 2;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOXD4_HUMAN|diamond]RecName: Full=Forkhead box protein D4; AltName: Full=Forkhead-related protein FKHL9; AltName: Full=Forkhead-related transcription factor 5; Short=FREAC-5; AltName: Full=Myeloid factor-alpha;+++[FX4L3_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 3; Short=FOXD4-like 3;+++[FX4L4_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 4 {ECO:0000305}; Short=FOXD4-like 4 {ECO:0000305}; AltName: Full=Forkhead box protein D4-like 2 {ECO:0000312|HGNC:HGNC:23762}; AltName: Full=Forkhead box protein D4B {ECO:0000305|PubMed:12234674}; AltName: Full=Myeloid factor-gamma {ECO:0000312|EMBL:AAL73342.1};+++[FX4L5_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 5; Short=FOXD4-like 5;+++[FX4L6_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 6; Short=FOXD4-like 6;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379473,"'LOC105379473'",0,0.25,0,0.0833333333333333,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0005524///ATP binding","GO:0042127///regulation of cell proliferation+++GO:0000165///MAPK cascade+++GO:0019933///cAMP-mediated signaling+++GO:0006468///protein phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0007265///Ras protein signal transduction+++GO:0043405///regulation of MAP kinase activity","uncharacterized LOC105379473","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105379474,"'LOC105379474'",0,0.25,0,0.0833333333333333,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0005524///ATP binding+++GO:0071889///14-3-3 protein binding+++GO:0008022///protein C-terminus binding+++GO:0051879///Hsp90 protein binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0004672///protein kinase activity","GO:0007265///Ras protein signal transduction+++GO:0006468///protein phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0000165///MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation","uncharacterized LOC105379474","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105379533,"'LOC105379533'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0032587///ruffle membrane+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0071889///14-3-3 protein binding+++GO:0051087///chaperone binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0005524///ATP binding+++GO:0008022///protein C-terminus binding","GO:0007265///Ras protein signal transduction+++GO:0043405///regulation of MAP kinase activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0000165///MAPK cascade+++GO:0042127///regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0019933///cAMP-mediated signaling","translation initiation factor IF-2-like","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[T53G3_HUMAN|diamond]RecName: Full=TP53-target gene 3 protein; AltName: Full=TP53-inducible gene 3 protein;"]
[105379545,"'LOC105379545'",0,0.25,0,0.0833333333333333,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0032587///ruffle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0071889///14-3-3 protein binding+++GO:0008022///protein C-terminus binding+++GO:0005524///ATP binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0031434///mitogen-activated protein kinase kinase binding","GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0019933///cAMP-mediated signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0007265///Ras protein signal transduction","uncharacterized LOC105379545","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105379547,"'LOC105379547'",8,8,0,5.33333333333333,{"$nulls":7},"paraneoplastic antigen Ma6E-like","[A0A2I2YCC5_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000032450};+++[A0A2I2YHS6_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000034480};+++[A0A2I2Z815_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000043246};+++[A0A2I3ST96_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000080167};+++[A0A2I3TT44_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000092156};"]
[105379554,"'LOC105379554'",37.97,56.14,65.29,53.1333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0036126///sperm flagellum+++GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0030317///flagellated sperm motility","maFF-interacting protein","[MAFIP_HUMAN|diamond]RecName: Full=MaFF-interacting protein; AltName: Full=Tektin-4 like protein PP5644;+++[TEKT4_BOVIN|diamond]RecName: Full=Tektin-4;+++[TEKT4_HUMAN|diamond]RecName: Full=Tektin-4;+++[TEKT4_MOUSE|diamond]RecName: Full=Tektin-4; AltName: Full=Testicular microtubules-related protein 4;+++[TEKT4_RAT|diamond]RecName: Full=Tektin-4;"]
[105379561,"'LOC105379561'",6,11,3.42,6.80666666666667,{"$nulls":7},"uncharacterized LOC105379561","[A0A0D9SCH2_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000018561};+++[A0A1A9ADJ3_9APIC|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:SBT54262.1};"]
[105379575,"'105379575'",3,2,12,5.66666666666667,{"$nulls":8},"[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A2_ASCSU|diamond]RecName: Full=Collagen alpha-2(IV) chain; Flags: Precursor;+++[CO4A2_CAEEL|diamond]RecName: Full=Collagen alpha-2(IV) chain; AltName: Full=Lethal protein 2; Flags: Precursor;+++[LWA_ANTEL|diamond]RecName: Full=LWamide neuropeptides; Contains: RecName: Full=LWamide I; Contains: RecName: Full=Metamorphosin A; Short=MMA; AltName: Full=LWamide II; Contains: RecName: Full=LWamide III; Contains: RecName: Full=LWamide IV; Contains: RecName: Full=LWamide V; Contains: RecName: Full=LWamide VI; Contains: RecName: Full=LWamide VII; Contains: RecName: Full=LWamide VIII; Contains: RecName: Full=LWamide IX; Flags: Precursor;+++[MUC2_HUMAN|diamond]RecName: Full=Mucin-2; Short=MUC-2; AltName: Full=Intestinal mucin-2; Flags: Precursor;"]
[105379752,"'LOC105379752'",2,6,2,3.33333333333333,{"$nulls":7},"uncharacterized LOC105379752","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[10539,"'GLRX3'",516,675,663,618,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005938///cell cortex+++GO:0030018///Z disc","GO:0009055///electron transfer activity+++GO:0003723///RNA binding+++GO:0015038///glutathione disulfide oxidoreductase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0051536///iron-sulfur cluster binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding","GO:0002026///regulation of the force of heart contraction+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0006879///cellular iron ion homeostasis+++GO:0022900///electron transport chain","glutaredoxin 3","[GLRX3_HUMAN|Reviewed]RecName: Full=Glutaredoxin-3; AltName: Full=PKC-interacting cousin of thioredoxin {ECO:0000303|PubMed:10636891}; Short=PICOT {ECO:0000303|PubMed:10636891}; AltName: Full=PKC-theta-interacting protein; Short=PKCq-interacting protein; AltName: Full=Thioredoxin-like protein 2;+++[A0A140VJK1_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 75 {ECO:0000313|EMBL:AEE60988.1};"]
[1054,"'CEBPG'",211,185,170,188.666666666667,"05152///Tuberculosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity","GO:0042267///natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0001889///liver development+++GO:0016071///mRNA metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043353///enucleate erythrocyte differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0043388///positive regulation of DNA binding+++GO:0030183///B cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity","CCAAT enhancer binding protein gamma","[CEBPG_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein gamma; Short=C/EBP gamma;"]
[10540,"'DCTN2'",1954,2331,2357,2214,"04962///Vasopressin-regulated water reabsorption+++05016///Huntington's disease",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0031982///vesicle+++GO:0005829///cytosol+++GO:0000776///kinetochore+++GO:0030426///growth cone+++GO:0005869///dynactin complex+++GO:0005813///centrosome+++GO:0030286///dynein complex+++GO:0016020///membrane","GO:0019901///protein kinase binding+++GO:0003774///motor activity+++GO:0030507///spectrin binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007017///microtubule-based process+++GO:0008283///cell proliferation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0071539///protein localization to centrosome+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007052///mitotic spindle organization+++GO:0032402///melanosome transport+++GO:0000086///G2/M transition of mitotic cell cycle","dynactin subunit 2","[DCTN2_HUMAN|Reviewed]RecName: Full=Dynactin subunit 2; AltName: Full=50 kDa dynein-associated polypeptide; AltName: Full=Dynactin complex 50 kDa subunit; Short=DCTN-50; AltName: Full=p50 dynamitin;+++[A8K8J9_HUMAN|Unreviewed]SubName: Full=Dynactin 2 (P50), isoform CRA_b {ECO:0000313|EMBL:EAW97028.1}; SubName: Full=cDNA FLJ31120 fis, clone IMR322000730, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG51555.1}; SubName: Full=cDNA FLJ77785 {ECO:0000313|EMBL:BAF85053.1};+++[B3KTX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38923 fis, clone NT2NE2011823, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG53236.1};+++[F8VRV7_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448606}; Flags: Fragment;+++[F8VW18_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449855}; Flags: Fragment;+++[F8VX93_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449710}; Flags: Fragment;+++[F8W0U6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447553};+++[F8W1I6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000446964};+++[H0YHL1_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447308}; Flags: Fragment;+++[H0YI98_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448937}; Flags: Fragment;+++[V9HW58_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 77 {ECO:0000313|EMBL:ACI46007.1};"]
[10541,"'ANP32B'",741,858,782,793.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0070063///RNA polymerase binding+++GO:0042393///histone binding+++GO:0005515///protein binding","GO:0046827///positive regulation of protein export from nucleus+++GO:0021591///ventricular system development+++GO:0001944///vasculature development+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0048839///inner ear development+++GO:0045596///negative regulation of cell differentiation+++GO:0006334///nucleosome assembly+++GO:0060021///roof of mouth development","acidic nuclear phosphoprotein 32 family member B","[AN32B_HUMAN|Reviewed]RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member B; AltName: Full=Acidic protein rich in leucines; AltName: Full=Putative HLA-DR-associated protein I-2; Short=PHAPI2; AltName: Full=Silver-stainable protein SSP29;"]
[10542,"'LAMTOR5'",396,415,490,433.666666666667,"05161///Hepatitis B+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0071986///Ragulator complex+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071230///cellular response to amino acid stimulus+++GO:0009615///response to virus+++GO:0043066///negative regulation of apoptotic process+++GO:0008361///regulation of cell size+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0061462///protein localization to lysosome+++GO:0007050///cell cycle arrest+++GO:0019079///viral genome replication","late endosomal/lysosomal adaptor, MAPK and MTOR activator 5","[LTOR5_HUMAN|Reviewed]RecName: Full=Ragulator complex protein LAMTOR5; AltName: Full=Hepatitis B virus X-interacting protein; Short=HBV X-interacting protein; Short=HBX-interacting protein; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5;+++[A0A0C4DGV4_HUMAN|Unreviewed]SubName: Full=Hepatitis B virus x interacting protein {ECO:0000313|EMBL:EAW56447.1}; SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000480529};+++[E9PLX3_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000435085};+++[R4GMU8_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000473357};"]
[10544,"'PROCR'",436,759,733,642.666666666667,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0038023///signaling receptor activity+++GO:0005515///protein binding","GO:0050819///negative regulation of coagulation+++GO:0007599///hemostasis+++GO:0007596///blood coagulation","protein C receptor","[EPCR_HUMAN|Reviewed]RecName: Full=Endothelial protein C receptor; AltName: Full=Activated protein C receptor; Short=APC receptor; AltName: Full=Endothelial cell protein C receptor; AltName: CD_antigen=CD201; Flags: Precursor;+++[A0A0U1RQQ4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489117}; Flags: Fragment;+++[A0A0U1RRC4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489456}; Flags: Fragment;"]
[10548,"'TM9SF1'",1753,2061,1994,1936,{"$nulls":4},"GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0000421///autophagosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005764///lysosome+++GO:0016021///integral component of membrane",null,"GO:0072657///protein localization to membrane+++GO:0006914///autophagy","transmembrane 9 superfamily member 1","[TM9S1_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 1; AltName: Full=MP70 protein family member; Short=hMP70; Flags: Precursor;+++[B4E3A9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PJC4_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PJM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PL78_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PMQ9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PNW2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PP24_HUMAN|Unreviewed]SubName: Full=Transmembrane 9 superfamily member 1 {ECO:0000313|Ensembl:ENSP00000436486}; Flags: Fragment;+++[E9PQY7_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PS99_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[G3V1B9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[10549,"'PRDX4'",1330,1285,1284,1299.66666666667,"04214///Apoptosis - fly",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0005623///cell+++GO:0005790///smooth endoplasmic reticulum+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0004601///peroxidase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0051920///peroxiredoxin activity+++GO:0016209///antioxidant activity+++GO:0008379///thioredoxin peroxidase activity","GO:0007252///I-kappaB phosphorylation+++GO:0045454///cell redox homeostasis+++GO:0072593///reactive oxygen species metabolic process+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification+++GO:0019471///4-hydroxyproline metabolic process+++GO:0006979///response to oxidative stress+++GO:2000255///negative regulation of male germ cell proliferation+++GO:0022417///protein maturation by protein folding+++GO:0008584///male gonad development+++GO:0043312///neutrophil degranulation+++GO:0007283///spermatogenesis+++GO:0055114///oxidation-reduction process+++GO:0030198///extracellular matrix organization","peroxiredoxin 4","[PRDX4_HUMAN|Reviewed]RecName: Full=Peroxiredoxin-4; EC=1.11.1.15 {ECO:0000269|PubMed:21916849, ECO:0000269|PubMed:9388242}; AltName: Full=Antioxidant enzyme AOE372; Short=AOE37-2; AltName: Full=Peroxiredoxin IV; Short=Prx-IV; AltName: Full=Thioredoxin peroxidase AO372; AltName: Full=Thioredoxin-dependent peroxide reductase A0372; Flags: Precursor;+++[A6NG45_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368635};+++[A6NJJ0_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368654}; Flags: Fragment;+++[H7C3T4_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000413736}; Flags: Fragment;+++[V9HW63_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 97n {ECO:0000313|EMBL:ACI45989.1}; SubName: Full=Peroxiredoxin 4 {ECO:0000313|EMBL:EAW98996.1};"]
[10550,"'ARL6IP5'",1686,2045,1909,1880,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0002037///negative regulation of L-glutamate import across plasma membrane+++GO:0015813///L-glutamate transmembrane transport+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential","ADP ribosylation factor like GTPase 6 interacting protein 5","[PRAF3_HUMAN|Reviewed]RecName: Full=PRA1 family protein 3; AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 5; Short=ARL-6-interacting protein 5; Short=Aip-5; AltName: Full=Cytoskeleton-related vitamin A-responsive protein; AltName: Full=Dermal papilla-derived protein 11; AltName: Full=GTRAP3-18; AltName: Full=Glutamate transporter EAAC1-interacting protein; AltName: Full=JM5; AltName: Full=Prenylated Rab acceptor protein 2; AltName: Full=Protein JWa; AltName: Full=Putative MAPK-activating protein PM27;+++[A0A024R371_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[C9JQU6_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF33_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF90_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10551,"'AGR2'",1,4,2,2.33333333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0042803///protein homodimerization activity+++GO:0002162///dystroglycan binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005515///protein binding","GO:0010628///positive regulation of gene expression+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:1903899///positive regulation of PERK-mediated unfolded protein response+++GO:0070254///mucus secretion+++GO:0034976///response to endoplasmic reticulum stress+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:0060480///lung goblet cell differentiation+++GO:0048639///positive regulation of developmental growth+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0060548///negative regulation of cell death+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0048546///digestive tract morphogenesis","anterior gradient 2, protein disulphide isomerase family member","[AGR2_HUMAN|Reviewed]RecName: Full=Anterior gradient protein 2 homolog; Short=AG-2; Short=hAG-2; AltName: Full=HPC8; AltName: Full=Secreted cement gland protein XAG-2 homolog; Flags: Precursor;+++[B5MC07_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000386025};+++[C9J3E2_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000411969}; Flags: Fragment;+++[H7C3Z9_HUMAN|Unreviewed]SubName: Full=Anterior gradient protein 2 homolog {ECO:0000313|Ensembl:ENSP00000414806}; Flags: Fragment;+++[Q4JM46_HUMAN|Unreviewed]SubName: Full=AGR2 {ECO:0000313|EMBL:AAY84774.1}; SubName: Full=Anterior gradient 2 homolog (Xenopus laevis) {ECO:0000313|EMBL:EAL24283.1}; SubName: Full=Anterior gradient 2 homolog (Xenopus laevis), isoform CRA_a {ECO:0000313|EMBL:EAW93682.1}; SubName: Full=Anterior gradient 2 splice variant C {ECO:0000313|EMBL:AJO53280.1}; SubName: Full=Epididymis secretory protein Li 116 {ECO:0000313|EMBL:ACI45999.1};+++[Q4JM47_HUMAN|Unreviewed]SubName: Full=AGR2 {ECO:0000313|EMBL:AAY84773.1};"]
[10552,"'ARPC1A'",1471,1428,1462,1453.66666666667,"05130///Pathogenic Escherichia coli infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++05131///Shigellosis",{"$nulls":3},"GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030833///regulation of actin filament polymerization+++GO:0061024///membrane organization","actin related protein 2/3 complex subunit 1A","[ARC1A_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1A; AltName: Full=SOP2-like protein;+++[A0A0K0K1L3_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 307 {ECO:0000313|EMBL:ACV87209.1}; Flags: Fragment;+++[E9PF58_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1A {ECO:0000313|Ensembl:ENSP00000408711};+++[Q75MY0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ARPC1A {ECO:0000313|EMBL:AAS00381.1}; Flags: Fragment;+++[V9HVZ6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};"]
[10553,"'HTATIP2'",147,126,106,126.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0045765///regulation of angiogenesis+++GO:0051170///import into nucleus+++GO:0030154///cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0016032///viral process+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development","HIV-1 Tat interactive protein 2","[HTAI2_HUMAN|Reviewed]RecName: Full=Oxidoreductase HTATIP2; EC=1.1.1.-; AltName: Full=30 kDa HIV-1 TAT-interacting protein; AltName: Full=HIV-1 TAT-interactive protein 2;+++[E9PI87_HUMAN|Unreviewed]SubName: Full=Oxidoreductase HTATIP2 {ECO:0000313|Ensembl:ENSP00000436729};"]
[10554,"'AGPAT1'",3833,4231,4565,4209.66666666667,"00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate+++R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0006629///lipid metabolic process+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0001819///positive regulation of cytokine production+++GO:0031325///positive regulation of cellular metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process","1-acylglycerol-3-phosphate O-acyltransferase 1","[PLCA_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 1; Short=1-AGP acyltransferase 1; Short=1-AGPAT 1; AltName: Full=Lysophosphatidic acid acyltransferase alpha; Short=LPAAT-alpha; AltName: Full=Protein G15; Flags: Precursor;+++[A0A024RCV5_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};"]
[10555,"'AGPAT2'",853,916,1056,941.666666666667,"00564///Glycerophospholipid metabolism+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA+++R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0035579///specific granule membrane","GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity","GO:0042493///response to drug+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008544///epidermis development+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0001819///positive regulation of cytokine production+++GO:0043312///neutrophil degranulation+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","1-acylglycerol-3-phosphate O-acyltransferase 2","[PLCB_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase beta; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2; Short=1-AGP acyltransferase 2; Short=1-AGPAT 2; AltName: Full=Lysophosphatidic acid acyltransferase beta; Short=LPAAT-beta; Flags: Precursor;+++[A0A024R8F9_HUMAN|Unreviewed]SubName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2 (Lysophosphatidic acid acyltransferase, beta), isoform CRA_b {ECO:0000313|EMBL:EAW88252.1}; SubName: Full=Testicular tissue protein Li 143 {ECO:0000313|EMBL:AEE61054.1};+++[A0A024R8I7_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q8WUW2_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q96IS9_HUMAN|Unreviewed]SubName: Full=AGPAT2 protein {ECO:0000313|EMBL:AAH07269.1}; Flags: Fragment;"]
[10556,"'RPP30'",116,126,166,136,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex+++GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004540///ribonuclease activity+++GO:0004526///ribonuclease P activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity","GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","ribonuclease P/MRP subunit p30","[RPP30_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p30; Short=RNaseP protein p30; EC=3.1.26.5; AltName: Full=RNase P subunit 2;+++[Q5VU10_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000407972}; Flags: Fragment;+++[Q5VU11_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000277882}; Flags: Fragment;"]
[10557,"'RPP38'",223,244,262,243,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090501///RNA phosphodiester bond hydrolysis","ribonuclease P/MRP subunit p38","[RPP38_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p38; Short=RNaseP protein p38; EC=3.1.26.5;+++[Q5VUC3_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000402635}; Flags: Fragment;+++[Q5VUC9_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000367443};"]
[10558,"'SPTLC1'",773,726,704,734.333333333333,"00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway+++01100///Metabolic pathways+++04138///Autophagy - yeast","H00265///Hereditary sensory and autonomic neuropathy (HSAN)","M00099///Sphingosine biosynthesis+++M00094///Ceramide biosynthesis","R01281///Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)   Palmitoyl-CoA + L-Serine <=> 3-Dehydrosphinganine + CoA + CO2","GO:0017059///serine C-palmitoyltransferase complex+++GO:0016020///membrane+++GO:0035339///SPOTS complex+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0030170///pyridoxal phosphate binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0004758///serine C-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0030148///sphingolipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0046511///sphinganine biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0046513///ceramide biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046512///sphingosine biosynthetic process+++GO:1904504///positive regulation of lipophagy","serine palmitoyltransferase long chain base subunit 1","[SPTC1_HUMAN|Reviewed]RecName: Full=Serine palmitoyltransferase 1; EC=2.3.1.50; AltName: Full=Long chain base biosynthesis protein 1; Short=LCB 1; AltName: Full=Serine-palmitoyl-CoA transferase 1; Short=SPT 1; Short=SPT1;+++[A0A024R277_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase, long chain base subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW62805.1};+++[A0A2R8Y4S0_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000493933};+++[A0A2R8Y6A2_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495388};+++[A0A2R8Y763_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495764}; Flags: Fragment;+++[L8E7V1_HUMAN|Unreviewed]SubName: Full=Alternative protein SPTLC1 {ECO:0000313|EMBL:CCQ43355.1};+++[Q6NUL7_HUMAN|Unreviewed]SubName: Full=SPTLC1 protein {ECO:0000313|EMBL:AAH68537.1};"]
[10559,"'SLC35A1'",70,70,55,65,"04137///Mitophagy - animal+++00970///Aminoacyl-tRNA biosynthesis+++04140///Autophagy - animal","H01392///Arthrogryposis, mental retardation, and seizures (AMRS)+++H00606///Early infantile epileptic encephalopathy+++H00119///Congenital disorders of glycosylation (CDG) type II","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03646///L-Arginine:tRNA(Arg) ligase (AMP-forming) ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)","GO:0005794///Golgi apparatus+++GO:0030173///integral component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0015136///sialic acid transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity+++GO:0005456///CMP-N-acetylneuraminate transmembrane transporter activity","GO:0015782///CMP-N-acetylneuraminate transmembrane transport+++GO:0008643///carbohydrate transport+++GO:0015739///sialic acid transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport+++GO:0006464///cellular protein modification process+++GO:0005975///carbohydrate metabolic process","solute carrier family 35 member A1","[S35A1_HUMAN|Reviewed]RecName: Full=CMP-sialic acid transporter; Short=CMP-SA-Tr; Short=CMP-Sia-Tr; AltName: Full=Solute carrier family 35 member A1;+++[A0A087WVM1_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|Ensembl:ENSP00000479535};+++[Q5W1L6_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65470.1};+++[Q5W1L7_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65469.1, ECO:0000313|Ensembl:ENSP00000358570};+++[Q6A0F2_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17781.1};+++[Q6A0F3_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17780.1};"]
[1056,"'CEL'",133,130,154,139,"04975///Fat digestion and absorption+++01100///Metabolic pathways+++00561///Glycerolipid metabolism+++00100///Steroid biosynthesis+++04972///Pancreatic secretion","H00410///Maturity onset diabetes of the young (MODY)","M00098///Acylglycerol degradation","R01462///cholesterol ester acylhydrolase   Cholesterol ester + H2O <=> Cholesterol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase   1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid+++R02250///triacylglycerol acylhydrolase   Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid","GO:0009986///cell surface+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0098793///presynapse+++GO:0005737///cytoplasm","GO:0004806///triglyceride lipase activity+++GO:0042043///neurexin family protein binding+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003824///catalytic activity+++GO:0038023///signaling receptor activity+++GO:0004771///sterol esterase activity+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016787///hydrolase activity","GO:0006629///lipid metabolic process+++GO:0044258///intestinal lipid catabolic process+++GO:0007158///neuron cell-cell adhesion+++GO:0016042///lipid catabolic process+++GO:0044241///lipid digestion+++GO:0006707///cholesterol catabolic process+++GO:0097104///postsynaptic membrane assembly+++GO:0050804///modulation of chemical synaptic transmission+++GO:0018350///protein esterification+++GO:0030299///intestinal cholesterol absorption+++GO:0097105///presynaptic membrane assembly+++GO:0009062///fatty acid catabolic process+++GO:0046514///ceramide catabolic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0030157///pancreatic juice secretion","carboxyl ester lipase","[CEL_HUMAN|Reviewed]RecName: Full=Bile salt-activated lipase; Short=BAL; EC=3.1.1.13; EC=3.1.1.3; AltName: Full=Bile salt-stimulated lipase; Short=BSSL; AltName: Full=Bucelipase; AltName: Full=Carboxyl ester lipase; AltName: Full=Cholesterol esterase; AltName: Full=Pancreatic lysophospholipase; AltName: Full=Sterol esterase; Flags: Precursor;+++[B4DSX9_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};+++[O75612_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[Q86SR3_HUMAN|Unreviewed]SubName: Full=CEL protein {ECO:0000313|EMBL:AAH42510.1};+++[X6R868_HUMAN|Unreviewed]SubName: Full=Bile salt-activated lipase {ECO:0000313|Ensembl:ENSP00000361151};"]
[10560,"'SLC19A2'",189,189,166,181.333333333333,"04977///Vitamin digestion and absorption","H01231///Biotin-responsive basal ganglia disease (BBGD)+++H01183///Thiamine-responsive megaloblastic anemia (TRMA)+++H01565///Wernicke encephalopathy",null,null,"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0015234///thiamine transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity","GO:0042723///thiamine-containing compound metabolic process+++GO:0071934///thiamine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0015888///thiamine transport+++GO:0035461///vitamin transmembrane transport+++GO:0015884///folic acid transport+++GO:0051180///vitamin transport","solute carrier family 19 member 2","[S19A2_HUMAN|Reviewed]RecName: Full=Thiamine transporter 1; Short=ThTr-1; Short=ThTr1; AltName: Full=Solute carrier family 19 member 2; AltName: Full=Thiamine carrier 1; Short=TC1;+++[A0A024R8Y5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_c {ECO:0000313|EMBL:EAW90847.1}; SubName: Full=Solute carrier family 19 member 2 isoform 1 {ECO:0000313|EMBL:ALQ33992.1};+++[A0A024R928_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_a {ECO:0000313|EMBL:EAW90845.1}; SubName: Full=Solute carrier family 19 member 2 isoform 2 {ECO:0000313|EMBL:ALQ33993.1};+++[A0A2R8Y5B5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_b {ECO:0000313|EMBL:EAW90844.1}; SubName: Full=Thiamine transporter 1 {ECO:0000313|Ensembl:ENSP00000494404};+++[B0FBR7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 thiamine transporter member 2 {ECO:0000313|EMBL:ABY51619.1}; Flags: Fragment;+++[E3UTN9_HUMAN|Unreviewed]SubName: Full=SLC19A2 solute carrier family 19 member 2 {ECO:0000313|EMBL:ADP24156.1}; Flags: Fragment;+++[I7BB09_HUMAN|Unreviewed]SubName: Full=Thiamnine trasporter protein {ECO:0000313|EMBL:AFO38177.2}; Flags: Fragment;+++[Q7Z7J1_HUMAN|Unreviewed]SubName: Full=Thiamine transporter THTR-1 {ECO:0000313|EMBL:AAP37965.1}; Flags: Fragment;"]
[10561,"'IFI44'",322,547,749,539.333333333333,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005525///GTP binding","GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0009615///response to virus","interferon induced protein 44","[IFI44_HUMAN|Reviewed]RecName: Full=Interferon-induced protein 44; Short=p44; AltName: Full=Microtubule-associated protein 44;+++[C9JUM8_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000399477}; Flags: Fragment;+++[H7C1F3_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000400001}; Flags: Fragment;"]
[10562,"'OLFM4'",2,1,3,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0042582///azurophil granule+++GO:1904724///tertiary granule lumen+++GO:0030141///secretory granule+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion+++GO:0005576///extracellular region+++GO:0042581///specific granule+++GO:0035580///specific granule lumen","GO:0003824///catalytic activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0010939///regulation of necrotic cell death+++GO:0042981///regulation of apoptotic process+++GO:0051260///protein homooligomerization+++GO:0007155///cell adhesion+++GO:0050764///regulation of phagocytosis+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0043312///neutrophil degranulation+++GO:2000389///regulation of neutrophil extravasation","olfactomedin 4","[OLFM4_HUMAN|Reviewed]RecName: Full=Olfactomedin-4; Short=OLM4; AltName: Full=Antiapoptotic protein GW112; AltName: Full=G-CSF-stimulated clone 1 protein; Short=hGC-1; AltName: Full=hOLfD; Flags: Precursor;+++[A0A024QZ95_HUMAN|Unreviewed]SubName: Full=Olfactomedin 4, isoform CRA_a {ECO:0000313|EMBL:EAW52053.1};"]
[10564,"'ARFGEF2'",1152,869,544,855,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0005829///cytosol+++GO:0005879///axonemal microtubule+++GO:0032279///asymmetric synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0043197///dendritic spine+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0030054///cell junction+++GO:0032280///symmetric synapse+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0005856///cytoskeleton+++GO:0055037///recycling endosome+++GO:0030425///dendrite+++GO:0005815///microtubule organizing center+++GO:0005768///endosome+++GO:0042995///cell projection","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0050811///GABA receptor binding","GO:0032012///regulation of ARF protein signal transduction+++GO:0006887///exocytosis+++GO:0001881///receptor recycling+++GO:0006893///Golgi to plasma membrane transport+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0007032///endosome organization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction","ADP ribosylation factor guanine nucleotide exchange factor 2","[BIG2_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Short=Brefeldin A-inhibited GEP 2; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2;+++[L8E9E5_HUMAN|Unreviewed]SubName: Full=Alternative protein ARFGEF2 {ECO:0000313|EMBL:CCQ43356.1};+++[Q59FR3_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2 variant {ECO:0000313|EMBL:BAD92634.1}; Flags: Fragment;+++[Q86TH5_HUMAN|Unreviewed]SubName: Full=ARFGEF2 protein {ECO:0000313|EMBL:AAH50449.1}; Flags: Fragment;"]
[10565,"'ARFGEF1'",1299,1126,772,1065.66666666667,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0000139///Golgi membrane+++GO:0016363///nuclear matrix+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005096///GTPase activator activity+++GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0051897///positive regulation of protein kinase B signaling+++GO:0090284///positive regulation of protein glycosylation in Golgi+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0034260///negative regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0090303///positive regulation of wound healing+++GO:0030837///negative regulation of actin filament polymerization+++GO:0006887///exocytosis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0031175///neuron projection development","ADP ribosylation factor guanine nucleotide exchange factor 1","[BIG1_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Short=Brefeldin A-inhibited GEP 1; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1; AltName: Full=p200 ARF guanine nucleotide exchange factor; AltName: Full=p200 ARF-GEP1;+++[A0A024R7X0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1(Brefeldin A-inhibited), isoform CRA_a {ECO:0000313|EMBL:EAW86936.1};+++[E5RHL7_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000430891}; Flags: Fragment;+++[E5RHZ1_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429560}; Flags: Fragment;+++[E5RIF2_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000428429}; Flags: Fragment;+++[E5RJN9_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429002}; Flags: Fragment;"]
[10566,"'AKAP3'",21,20,27,22.6666666666667,{"$nulls":4},"GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0097228///sperm principal piece","GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0007340///acrosome reaction+++GO:0008104///protein localization+++GO:0007338///single fertilization+++GO:0001835///blastocyst hatching+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway","A-kinase anchoring protein 3","[AKAP3_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 3; Short=AKAP-3; AltName: Full=A-kinase anchor protein 110 kDa; Short=AKAP 110; AltName: Full=Cancer/testis antigen 82; Short=CT82; AltName: Full=Fibrous sheath protein of 95 kDa; Short=FSP95; AltName: Full=Fibrousheathin I; AltName: Full=Fibrousheathin-1; AltName: Full=Protein kinase A-anchoring protein 3; Short=PRKA3; AltName: Full=Sperm oocyte-binding protein;+++[F5H2S4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000439382}; Flags: Fragment;+++[F5H7P4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000442376}; Flags: Fragment;+++[V9HWD4_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 159 {ECO:0000313|EMBL:ACJ13735.1};"]
[10567,"'RABAC1'",1761,2232,2355,2116,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0005794///Golgi apparatus+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0070064///proline-rich region binding",null,"Rab acceptor 1","[PRAF1_HUMAN|Reviewed]RecName: Full=Prenylated Rab acceptor protein 1; AltName: Full=PRA1 family protein 1;+++[M0QXH1_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0QXU8_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[M0R1H9_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0R3D4_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10568,"'SLC34A2'",0,0,4,1.33333333333333,"04928///Parathyroid hormone synthesis, secretion and action","H00888///Nephrolithiasis/osteoporosis, hypophosphatemic+++H02138///Hereditary hypophophatemic rickets with hypercalciuria+++H01198///Fanconi renotubular syndrome (FTS)+++H00214///Hypophosphatemic rickets+++H01298///Pulmonary alveolar microlithiasis (PALM)",null,null,"GO:0031982///vesicle+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0016020///membrane+++GO:0005903///brush border","GO:0042301///phosphate ion binding+++GO:0015321///sodium-dependent phosphate transmembrane transporter activity+++GO:0015293///symporter activity+++GO:0005436///sodium:phosphate symporter activity+++GO:0031402///sodium ion binding","GO:0006817///phosphate ion transport+++GO:0001701///in utero embryonic development+++GO:0055085///transmembrane transport+++GO:0030643///cellular phosphate ion homeostasis+++GO:0006811///ion transport+++GO:0044267///cellular protein metabolic process+++GO:0043627///response to estrogen+++GO:0044341///sodium-dependent phosphate transport+++GO:0035725///sodium ion transmembrane transport+++GO:0006814///sodium ion transport","solute carrier family 34 member 2","[NPT2B_HUMAN|Reviewed]RecName: Full=Sodium-dependent phosphate transport protein 2B; Short=Sodium-phosphate transport protein 2B; AltName: Full=Na(+)-dependent phosphate cotransporter 2B; AltName: Full=NaPi3b; AltName: Full=Sodium/phosphate cotransporter 2B; Short=Na(+)/Pi cotransporter 2B; Short=NaPi-2b; AltName: Full=Solute carrier family 34 member 2;+++[A0A0B5E3E9_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|EMBL:AJE59606.1}; Flags: Fragment;+++[D6RA94_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|Ensembl:ENSP00000423038}; Flags: Fragment;+++[D6RBC0_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transport protein 2B {ECO:0000313|Ensembl:ENSP00000424266}; Flags: Fragment;"]
[10569,"'SLU7'",519,576,522.05,539.016666666667,"03040///Spliceosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0030628///pre-mRNA 3'-splice site binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0000386///second spliceosomal transesterification activity","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006406///mRNA export from nucleus+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000389///mRNA 3'-splice site recognition+++GO:0034605///cellular response to heat+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0006886///intracellular protein transport","SLU7 homolog, splicing factor","[SLU7_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SLU7; Short=hSlu7;+++[A0A0C4DGD2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428362}; Flags: Fragment;+++[E5RGM7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000429990}; Flags: Fragment;+++[E5RK41_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428943}; Flags: Fragment;"]
[10570,"'DPYSL4'",1089,1396,1408,1297.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0031005///filamin binding","GO:0097485///neuron projection guidance+++GO:0070997///neuron death+++GO:0007399///nervous system development","dihydropyrimidinase like 4","[DPYL4_HUMAN|Reviewed]RecName: Full=Dihydropyrimidinase-related protein 4; Short=DRP-4; AltName: Full=Collapsin response mediator protein 3; Short=CRMP-3; AltName: Full=UNC33-like phosphoprotein 4; Short=ULIP-4;+++[D3DRG7_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-like 4, isoform CRA_a {ECO:0000313|EMBL:EAW49133.1};+++[Q5T0Q6_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-related protein 4 {ECO:0000313|Ensembl:ENSP00000357616};"]
[10572,"'SIVA1'",195,189,237,207,"04115///p53 signaling pathway",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0001618///virus receptor activity+++GO:0046872///metal ion binding+++GO:0005175///CD27 receptor binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0008270///zinc ion binding","GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006915///apoptotic process+++GO:0046718///viral entry into host cell+++GO:0006924///activation-induced cell death of T cells+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0016032///viral process+++GO:0097191///extrinsic apoptotic signaling pathway","SIVA1 apoptosis inducing factor","[SIVA_HUMAN|Reviewed]RecName: Full=Apoptosis regulatory protein Siva; AltName: Full=CD27-binding protein; Short=CD27BP;+++[B4DTY2_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79449, highly similar to Apoptosis regulatory protein Siva {ECO:0000313|EMBL:BAG65628.1};+++[G3V3U1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451427};+++[G3V439_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451570}; Flags: Fragment;+++[H0YJN1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451823};"]
[10573,"'MRPL28'",956,1036,1214,1068.66666666667,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005761///mitochondrial ribosome+++GO:0005739///mitochondrion","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","mitochondrial ribosomal protein L28","[RM28_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L28, mitochondrial; Short=L28mt; Short=MRP-L28; AltName: Full=Melanoma antigen p15; AltName: Full=Melanoma-associated antigen recognized by T-lymphocytes; AltName: Full=Mitochondrial large ribosomal subunit protein bL28m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[P13986_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:CAA34647.1};+++[Q9NRK2_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAF76751.1};+++[Q9UM95_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAD14186.1}; Flags: Fragment;"]
[10574,"'CCT7'",2218,2331,2537,2362,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0005874///microtubule+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0050821///protein stabilization+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0006457///protein folding","chaperonin containing TCP1 subunit 7","[TCPH_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit eta; Short=TCP-1-eta; AltName: Full=CCT-eta; AltName: Full=HIV-1 Nef-interacting protein; Contains: RecName: Full=T-complex protein 1 subunit eta, N-terminally processed;+++[A0A0D9SG95_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[B7Z1C9_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[F8WAM2_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042}; Flags: Fragment;+++[F8WBP8_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[Q6IBT3_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};"]
[10575,"'CCT4'",1477,1559,1568,1534.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005832///chaperonin-containing T-complex+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0002199///zona pellucida receptor complex+++GO:0042470///melanosome+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0005874///microtubule","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0051082///unfolded protein binding","GO:1904871///positive regulation of protein localization to Cajal body+++GO:0090666///scaRNA localization to Cajal body+++GO:0006457///protein folding+++GO:0050821///protein stabilization+++GO:0051973///positive regulation of telomerase activity+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida","chaperonin containing TCP1 subunit 4","[TCPD_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit delta; Short=TCP-1-delta; AltName: Full=CCT-delta; AltName: Full=Stimulator of TAR RNA-binding;"]
[10576,"'CCT2'",1143,1164,1255,1187.33333333333,{"$nulls":4},"GO:0044297///cell body+++GO:0043209///myelin sheath+++GO:0005874///microtubule+++GO:0002199///zona pellucida receptor complex+++GO:0005829///cytosol+++GO:0035578///azurophil granule lumen+++GO:0005832///chaperonin-containing T-complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005524///ATP binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0050821///protein stabilization+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:0051086///chaperone mediated protein folding independent of cofactor+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0090666///scaRNA localization to Cajal body+++GO:0007339///binding of sperm to zona pellucida+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0043312///neutrophil degranulation+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0006457///protein folding","chaperonin containing TCP1 subunit 2","[TCPB_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;+++[F5GWF6_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000441847};+++[F8VQ14_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000450153};+++[V9HW96_HUMAN|Unreviewed]SubName: Full=Chaperonin containing TCP1, subunit 2 (Beta), isoform CRA_b {ECO:0000313|EMBL:EAW97229.1}; SubName: Full=Epididymis secretory sperm binding protein Li 100n {ECO:0000313|EMBL:ACI46043.1};"]
[10577,"'NPC2'",11493,11431,12819,11914.3333333333,"04142///Lysosome+++04979///Cholesterol metabolism","H00136///Niemann-Pick disease type C (NPC)",null,null,"GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035578///azurophil granule lumen+++GO:0043202///lysosomal lumen+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005623///cell","GO:0019899///enzyme binding+++GO:0017127///cholesterol transporter activity+++GO:0015485///cholesterol binding+++GO:0005515///protein binding","GO:0030301///cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0046836///glycolipid transport+++GO:0015914///phospholipid transport+++GO:0032366///intracellular sterol transport+++GO:0008202///steroid metabolic process+++GO:0043312///neutrophil degranulation+++GO:0042632///cholesterol homeostasis+++GO:0006869///lipid transport+++GO:0034383///low-density lipoprotein particle clearance+++GO:0019747///regulation of isoprenoid metabolic process+++GO:0006629///lipid metabolic process+++GO:0009615///response to virus+++GO:0032367///intracellular cholesterol transport+++GO:0008203///cholesterol metabolic process","NPC intracellular cholesterol transporter 2","[NPC2_HUMAN|Reviewed]RecName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000312|HGNC:HGNC:14537}; AltName: Full=Epididymal secretory protein E1; AltName: Full=Human epididymis-specific protein 1; Short=He1 {ECO:0000303|PubMed:11125141, ECO:0000303|PubMed:8418812}; AltName: Full=Niemann-Pick disease type C2 protein {ECO:0000303|PubMed:17018531}; Flags: Precursor;+++[A0A024R6C0_HUMAN|Unreviewed]SubName: Full=Niemann-Pick disease, type C2, isoform CRA_a {ECO:0000313|EMBL:EAW81177.1};+++[E7EMS2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000412103};+++[G3V2V8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450887}; Flags: Fragment;+++[G3V3D1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451180}; Flags: Fragment;+++[G3V3E8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451206};+++[H0YIZ1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450502}; Flags: Fragment;+++[H0YJE2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451314}; Flags: Fragment;+++[J3KMY5_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000238633};"]
[10579,"'TACC2'",573,560,392,508.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0035257///nuclear hormone receptor binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization","transforming acidic coiled-coil containing protein 2","[TACC2_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 2; AltName: Full=Anti-Zuai-1; Short=AZU-1;+++[A0A0U1RRM9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489610}; Flags: Fragment;+++[B2RWP4_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI50628.1};+++[B7ZMJ9_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI44600.1};+++[D6RAA5_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422815};+++[E7EMZ9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000427618};+++[E9PBC6_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424467};+++[E9PGB3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000420967}; Flags: Fragment;+++[H0Y8P9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000421702}; Flags: Fragment;+++[H0Y911_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422725}; Flags: Fragment;+++[H0Y954_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423069}; Flags: Fragment;+++[H0Y9C3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423764}; Flags: Fragment;+++[H0Y9Y7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425525}; Flags: Fragment;+++[H0YA73_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000426303}; Flags: Fragment;+++[Q4VXL4_HUMAN|Unreviewed]SubName: Full=HCG41426, isoform CRA_c {ECO:0000313|EMBL:EAW49324.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357997};+++[Q4VXL8_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357995};"]
[1058,"'CENPA'",0,0,3,1,{"$nulls":4},"GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000786///nucleosome+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0000775///chromosome, centromeric region+++GO:0000939///condensed chromosome inner kinetochore+++GO:0000788///nuclear nucleosome+++GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0031618///nuclear pericentric heterochromatin","GO:0003682///chromatin binding+++GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0016032///viral process+++GO:0000132///establishment of mitotic spindle orientation+++GO:0006334///nucleosome assembly+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0051382///kinetochore assembly+++GO:0000281///mitotic cytokinesis","centromere protein A","[CENPA_HUMAN|Reviewed]RecName: Full=Histone H3-like centromeric protein A; AltName: Full=Centromere autoantigen A; AltName: Full=Centromere protein A; Short=CENP-A;+++[F8WD88_HUMAN|Unreviewed]SubName: Full=Histone H3-like centromeric protein A {ECO:0000313|Ensembl:ENSP00000404963};"]
[10580,"'SORBS1'",301,199,228,242.666666666667,"03320///PPAR signaling pathway+++04910///Insulin signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005899///insulin receptor complex+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0045121///membrane raft+++GO:0005924///cell-substrate adherens junction+++GO:0005813///centrosome+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0005915///zonula adherens+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix+++GO:0005913///cell-cell adherens junction","GO:0005515///protein binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005158///insulin receptor binding+++GO:0008092///cytoskeletal protein binding+++GO:0003779///actin binding","GO:0048041///focal adhesion assembly+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046326///positive regulation of glucose import+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0043149///stress fiber assembly+++GO:0032869///cellular response to insulin stimulus+++GO:0006936///muscle contraction+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007160///cell-matrix adhesion+++GO:0007015///actin filament organization","sorbin and SH3 domain containing 1","[SRBS1_HUMAN|Reviewed]RecName: Full=Sorbin and SH3 domain-containing protein 1; AltName: Full=Ponsin; AltName: Full=SH3 domain protein 5; AltName: Full=SH3P12; AltName: Full=c-Cbl-associated protein; Short=CAP;+++[A0A0U1RQI5_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000489022}; Flags: Fragment;+++[B4DTX5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60072, highly similar to Homo sapiens sorbin and SH3 domain containing 1 (SORBS1), transcript variant 6, mRNA {ECO:0000313|EMBL:BAG62137.1};+++[D3DR43_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain containing 1, isoform CRA_e {ECO:0000313|EMBL:EAW50004.1};+++[Q5T925_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000360272}; Flags: Fragment;+++[S4R303_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000473813}; Flags: Fragment;+++[S4R406_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000474932}; Flags: Fragment;"]
[10581,"'IFITM2'",1280,1661,2570,1837,"04662///B cell receptor signaling pathway","H00506///Osteogenesis imperfecta",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0005886///plasma membrane",null,"GO:0035456///response to interferon-beta+++GO:0035455///response to interferon-alpha+++GO:0051607///defense response to virus+++GO:0009615///response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0006955///immune response+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0034341///response to interferon-gamma+++GO:0046597///negative regulation of viral entry into host cell+++GO:0002376///immune system process","interferon induced transmembrane protein 2","[IFM2_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 2; AltName: Full=Dispanin subfamily A member 2c; Short=DSPA2c; AltName: Full=Interferon-inducible protein 1-8D;+++[E9PQN9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000434443};+++[H0YCL2_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000431850}; Flags: Fragment;+++[H7BYV1_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000382712}; Flags: Fragment;+++[Q6IBB0_HUMAN|Unreviewed]SubName: Full=IFITM2 protein {ECO:0000313|EMBL:CAG33175.1}; SubName: Full=Interferon induced transmembrane protein 2 (1-8D) {ECO:0000313|EMBL:AAP88861.1};"]
[10585,"'POMT1'",947,972,1012,977,"00515///Mannose type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++01100///Metabolic pathways","H01960///Muscular dystrophy-dystroglycanopathy type B+++H00593///Limb-girdle muscular dystrophy (LGMD)+++H00120///Muscular dystrophy-dystroglycanopathy type A+++H01959///Muscular dystrophy-dystroglycanopathy type C+++H00590///Congenital muscular dystrophies (CMD/MDC)",null,"R07620///Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027+++R04072///dolichyl-beta-D-mannosyl-phosphate:protein-serine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]+++R11399///dolichyl-beta-D-mannosyl-phosphate:protein-threonine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein]","GO:0016021///integral component of membrane+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0097502///mannosylation+++GO:0030198///extracellular matrix organization+++GO:0035269///protein O-linked mannosylation+++GO:0007275///multicellular organism development+++GO:0006486///protein glycosylation+++GO:1904100///positive regulation of protein O-linked glycosylation+++GO:0005975///carbohydrate metabolic process+++GO:0006493///protein O-linked glycosylation","protein O-mannosyltransferase 1","[POMT1_HUMAN|Reviewed]RecName: Full=Protein O-mannosyl-transferase 1; EC=2.4.1.109; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 1;+++[A0A140VKE0_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 57p {ECO:0000313|EMBL:AEE61277.1};+++[A0A1L6C7Q4_HUMAN|Unreviewed]SubName: Full=Truncated O-mannosyl-transferase 1 variant SV3DEL {ECO:0000313|EMBL:APQ46216.1}; EC=2.4.1.109 {ECO:0000313|EMBL:APQ46216.1};+++[A0A1V1FTP4_HUMAN|Unreviewed]SubName: Full=POMT1 protein {ECO:0000313|EMBL:BAX07485.1};+++[Q5JSZ6_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000390737}; Flags: Fragment;+++[Q5JT02_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000361294}; Flags: Fragment;+++[Q5JT03_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000395060}; Flags: Fragment;+++[Q5JT04_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000405149}; Flags: Fragment;+++[Q5JT05_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000402083}; Flags: Fragment;+++[Q5JT07_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000403736}; Flags: Fragment;"]
[10586,"'MAB21L2'",1179,986,1174,1113,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0043010///camera-type eye development+++GO:0010172///embryonic body morphogenesis+++GO:0007399///nervous system development+++GO:0001654///eye development+++GO:0008284///positive regulation of cell proliferation","mab-21 like 2","[MB212_HUMAN|Reviewed]RecName: Full=Protein mab-21-like 2;"]
[10587,"'TXNRD2'",397,336,444,392.333333333333,"05225///Hepatocellular carcinoma+++05200///Pathways in cancer+++00450///Selenocompound metabolism","H00256///Familial glucocorticoid deficiency (FGD)",null,"R09372///methaneselenol:NADP+ oxidoreductase   2 NADPH + 2 H+ + Methylselenic acid <=> 2 NADP+ + 2 H2O + Methaneselenol+++R03596///hydrogen selenide:NADP+ oxidoreductase   Hydrogen selenide + 3 NADP+ + 3 H2O <=> Selenite + 3 NADPH + 5 H+","GO:0005623///cell+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0050660///flavin adenine dinucleotide binding+++GO:0004791///thioredoxin-disulfide reductase activity+++GO:0009055///electron transfer activity","GO:0034599///cellular response to oxidative stress+++GO:0022900///electron transport chain+++GO:0055114///oxidation-reduction process+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification+++GO:0000305///response to oxygen radical","thioredoxin reductase 2","[TRXR2_HUMAN|Reviewed]RecName: Full=Thioredoxin reductase 2, mitochondrial; EC=1.8.1.9; AltName: Full=Selenoprotein Z; Short=SelZ; AltName: Full=TR-beta; AltName: Full=Thioredoxin reductase TR3; Flags: Precursor;+++[A0A096LNY7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485290}; Flags: Fragment;+++[A0A096LP96_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485466};+++[A0A096LPB7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485499};+++[A0A096LPD9_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485543};+++[A0A096LPH4_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485603};+++[A0A096LPK7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485665};+++[A0A0U1RQX0_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000489208}; Flags: Fragment;+++[A0A182DWF2_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383362};+++[A0A182DWF3_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383363};+++[A4FTY4_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAH99923.1};+++[D3YTF8_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383369};+++[E7EWK1_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000334451};+++[Q17RE6_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAI17355.1};"]
[10588,"'MTHFS'",117,94,89,100,"00670///One carbon pool by folate+++01100///Metabolic pathways",null,null,"R02301///5-Formyltetrahydrofolate cyclo-ligase (ADP-forming)   ATP + Folinic acid + H+ <=> ADP + Orthophosphate + 5,10-Methenyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix","GO:0005542///folic acid binding+++GO:0005524///ATP binding+++GO:0030272///5-formyltetrahydrofolate cyclo-ligase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016874///ligase activity","GO:0006536///glutamate metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0015942///formate metabolic process+++GO:0046655///folic acid metabolic process+++GO:0046657///folic acid catabolic process+++GO:0009396///folic acid-containing compound biosynthetic process+++GO:0035999///tetrahydrofolate interconversion","methenyltetrahydrofolate synthetase","[MTHFS_HUMAN|Reviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase; EC=6.3.3.2; AltName: Full=5,10-methenyl-tetrahydrofolate synthetase; Short=MTHFS; Short=Methenyl-THF synthetase;+++[A0A0U1RQM3_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279};+++[H3BMB9_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454318}; Flags: Fragment;+++[H3BN04_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454626};+++[Q96EE9_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279}; Flags: Fragment;"]
[10589,"'DRAP1'",504,507,716,575.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","DR1 associated protein 1","[NC2A_HUMAN|Reviewed]RecName: Full=Dr1-associated corepressor; AltName: Full=Dr1-associated protein 1; AltName: Full=Negative cofactor 2-alpha; Short=NC2-alpha;+++[C9JCC6_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000366190};+++[E9PMW2_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437287};+++[E9PNC7_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437225}; Flags: Fragment;+++[E9PQX9_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000432445};"]
[1059,"'CENPB'",1782,1899,2075,1918.66666666667,{"$nulls":4},"GO:0016604///nuclear body+++GO:0031618///nuclear pericentric heterochromatin+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0005634///nucleus","GO:0003696///satellite DNA binding+++GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0019237///centromeric DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding",null,"centromere protein B","[CENPB_HUMAN|Reviewed]RecName: Full=Major centromere autoantigen B; AltName: Full=Centromere protein B; Short=CENP-B;"]
[10590,"'SCGN'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0030658///transport vesicle membrane+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0098793///presynapse","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0008150///biological_process+++GO:1900271///regulation of long-term synaptic potentiation+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0051480///regulation of cytosolic calcium ion concentration","secretagogin, EF-hand calcium binding protein","[SEGN_HUMAN|Reviewed]RecName: Full=Secretagogin;+++[Q96P10_HUMAN|Unreviewed]SubName: Full=Secretagogin, EF-hand calcium binding protein, isoform CRA_b {ECO:0000313|EMBL:EAW55488.1}; SubName: Full=Setagin {ECO:0000313|EMBL:AAL16052.1};"]
[10591,"'DNPH1'",370,338,459,389,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0070694///deoxyribonucleoside 5'-monophosphate N-glycosidase activity+++GO:0042803///protein homodimerization activity+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0016798///hydrolase activity, acting on glycosyl bonds","GO:0008152///metabolic process+++GO:0009159///deoxyribonucleoside monophosphate catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0009116///nucleoside metabolic process+++GO:0006195///purine nucleotide catabolic process+++GO:0008283///cell proliferation+++GO:0009117///nucleotide metabolic process+++GO:0030307///positive regulation of cell growth","2'-deoxynucleoside 5'-phosphate N-hydrolase 1","[DNPH1_HUMAN|Reviewed]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036, ECO:0000269|PubMed:24260472, ECO:0000269|PubMed:25108359}; AltName: Full=c-Myc-responsive protein RCL {ECO:0000255|HAMAP-Rule:MF_03036};+++[H0Y8X4_HUMAN|Unreviewed]SubName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000313|Ensembl:ENSP00000422440}; Flags: Fragment;"]
[10592,"'SMC2'",210,261,180,217,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0070062///extracellular exosome+++GO:0005730///nucleolus+++GO:0000228///nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0046982///protein heterodimerization activity","GO:0051301///cell division+++GO:0045132///meiotic chromosome segregation+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0051383///kinetochore organization","structural maintenance of chromosomes 2","[SMC2_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 2; Short=SMC protein 2; Short=SMC-2; AltName: Full=Chromosome-associated protein E; Short=hCAP-E; AltName: Full=XCAP-E homolog;+++[A0A024R158_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[A8K984_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B3KMB1_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B7ZLZ7_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[Q05BV1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH32705.1}; Flags: Fragment;+++[Q05D74_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH17845.1}; Flags: Fragment;+++[Q6IPS5_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH71750.1}; Flags: Fragment;+++[Q7Z2X1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH55081.1}; Flags: Fragment;"]
[10594,"'PRPF8'",8124,7704,6400,7409.33333333333,"03040///Spliceosome","H00527///Retinitis pigmentosa (RP)","M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005682///U5 snRNP+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0016020///membrane","GO:0000386///second spliceosomal transesterification activity+++GO:0097157///pre-mRNA intronic binding+++GO:0030623///U5 snRNA binding+++GO:0003723///RNA binding+++GO:0030620///U2 snRNA binding+++GO:0017070///U6 snRNA binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0030619///U1 snRNA binding+++GO:0005515///protein binding","GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0006397///mRNA processing+++GO:0071356///cellular response to tumor necrosis factor+++GO:0008380///RNA splicing","pre-mRNA processing factor 8","[PRP8_HUMAN|Reviewed]RecName: Full=Pre-mRNA-processing-splicing factor 8; AltName: Full=220 kDa U5 snRNP-specific protein; AltName: Full=PRP8 homolog; AltName: Full=Splicing factor Prp8; AltName: Full=p220;+++[I3L0J9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000458151}; Flags: Fragment;+++[I3L1T8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000459095}; Flags: Fragment;+++[I3L3Z8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000460849}; Flags: Fragment;"]
[10595,"'ERN2'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:1990604///IRE1-TRAF2-ASK1 complex","GO:0000166///nucleotide binding+++GO:0004540///ribonuclease activity+++GO:0004519///endonuclease activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0003824///catalytic activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0000287///magnesium ion binding","GO:0006397///mRNA processing+++GO:0007050///cell cycle arrest+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008152///metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0030263///apoptotic chromosome condensation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0007257///activation of JUN kinase activity+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0016075///rRNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis","endoplasmic reticulum to nucleus signaling 2","[ERN2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2; AltName: Full=Endoplasmic reticulum-to-nucleus signaling 2; AltName: Full=Inositol-requiring protein 2; Short=hIRE2p; AltName: Full=Ire1-beta; Short=IRE1b; Includes: RecName: Full=Serine/threonine-protein kinase; EC=2.7.11.1; Includes: RecName: Full=Endoribonuclease; EC=3.1.26.-; Flags: Precursor;+++[A5YM46_HUMAN|Unreviewed]SubName: Full=ERN2 protein {ECO:0000313|EMBL:ABQ59030.1};+++[A5YM65_HUMAN|Unreviewed]SubName: Full=ERN2 protein {ECO:0000313|EMBL:ABQ59049.1};+++[E7ETG2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000413812};+++[H3BSU1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000456866}; Flags: Fragment;+++[H3BTW8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000457361};+++[H3BUU2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase/endoribonuclease IRE2 {ECO:0000313|Ensembl:ENSP00000457796};"]
[10597,"'TRAPPC2B'",22.89,14.63,24.01,20.51,null,"H00760///Spondyloepiphyseal dysplasia tarda",null,null,"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0008134///transcription factor binding+++GO:0044325///ion channel binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport","trafficking protein particle complex 2B","[TPC2A_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2; AltName: Full=Sedlin;+++[TPC2B_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2B; AltName: Full=MBP-1-interacting protein 2A; Short=MIP-2A;+++[TPPC2_BOVIN|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_CANLF|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_PONAB|diamond]RecName: Full=Trafficking protein particle complex subunit 2;"]
[10598,"'AHSA1'",895,962,1018,958.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0001671///ATPase activator activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0032781///positive regulation of ATPase activity","activator of HSP90 ATPase activity 1","[AHSA1_HUMAN|Reviewed]RecName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1; Short=AHA1; AltName: Full=p38;+++[G3V3W9_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451467};+++[G3V438_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451569}; Flags: Fragment;+++[H0YJ63_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000450890}; Flags: Fragment;+++[H0YJG7_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451475}; Flags: Fragment;+++[H0YJU2_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000452127}; Flags: Fragment;"]
[1060,"'CENPC'",118,110,86,104.666666666667,{"$nulls":4},"GO:0031618///nuclear pericentric heterochromatin+++GO:0000776///kinetochore+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0090543///Flemming body+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0030496///midbody+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0032154///cleavage furrow","GO:0003677///DNA binding+++GO:0019237///centromeric DNA binding","GO:0007059///chromosome segregation+++GO:0000278///mitotic cell cycle+++GO:0051455///attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation+++GO:0051382///kinetochore assembly+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division","centromere protein C","[CENPC_HUMAN|Reviewed]RecName: Full=Centromere protein C; Short=CENP-C; AltName: Full=Centromere autoantigen C; AltName: Full=Centromere protein C 1; Short=CENP-C 1; AltName: Full=Interphase centromere complex protein 7;"]
[10600,"'USP16'",339,317,298,318,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0035578///azurophil granule lumen+++GO:0070062///extracellular exosome+++GO:0044297///cell body+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0002199///zona pellucida receptor complex+++GO:0045111///intermediate filament cytoskeleton+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005874///microtubule+++GO:0034774///secretory granule lumen","GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0042393///histone binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0044183///protein binding involved in protein folding+++GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0043130///ubiquitin binding+++GO:0045296///cadherin binding+++GO:0005524///ATP binding+++GO:0042623///ATPase activity, coupled+++GO:0004197///cysteine-type endopeptidase activity+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0016578///histone deubiquitination+++GO:0045901///positive regulation of translational elongation+++GO:0000278///mitotic cell cycle+++GO:0046931///pore complex assembly+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061077///chaperone-mediated protein folding+++GO:0051726///regulation of cell cycle+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0051289///protein homotetramerization+++GO:0006351///transcription, DNA-templated+++GO:0043312///neutrophil degranulation+++GO:0051301///cell division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006458///'de novo' protein folding+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0140014///mitotic nuclear division+++GO:0016579///protein deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0007339///binding of sperm to zona pellucida","ubiquitin specific peptidase 16","[UBP16_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; EC=3.4.19.12 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Deubiquitinating enzyme 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin thioesterase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin-processing protease UBP-M; AltName: Full=Ubiquitin-specific-processing protease 16 {ECO:0000255|HAMAP-Rule:MF_03062};"]
[10602,"'CDC42EP3'",1861,1835,1816,1837.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system","GO:0005515///protein binding+++GO:0005519///cytoskeletal regulatory protein binding+++GO:0017049///GTP-Rho binding","GO:0008360///regulation of cell shape+++GO:0007165///signal transduction+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization","CDC42 effector protein 3","[BORG2_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 3; AltName: Full=Binder of Rho GTPases 2; AltName: Full=MSE55-related Cdc42-binding protein;+++[C9J7F7_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000398062}; Flags: Fragment;+++[C9JEZ4_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000403298}; Flags: Fragment;+++[C9JKW5_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000409147}; Flags: Fragment;"]
[10603,"'SH2B2'",76,72,76,74.6666666666667,"04910///Insulin signaling pathway+++04722///Neurotrophin signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0035591///signaling adaptor activity+++GO:0008236///serine-type peptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008269///JAK pathway signal transduction adaptor activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0016787///hydrolase activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0004252///serine-type endopeptidase activity","GO:0009967///positive regulation of signal transduction+++GO:0007165///signal transduction+++GO:0001922///B-1 B cell homeostasis+++GO:0006508///proteolysis+++GO:0007399///nervous system development+++GO:0046578///regulation of Ras protein signal transduction+++GO:0007596///blood coagulation+++GO:0050776///regulation of immune response+++GO:0008286///insulin receptor signaling pathway+++GO:0046425///regulation of JAK-STAT cascade+++GO:0050873///brown fat cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0019222///regulation of metabolic process","SH2B adaptor protein 2","[SH2B2_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 2; AltName: Full=Adapter protein with pleckstrin homology and Src homology 2 domains; AltName: Full=SH2 and PH domain-containing adapter protein APS;+++[A0A087X016_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000483034};+++[C9JK89_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000401883}; Flags: Fragment;+++[Q15098_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59997.1}; Flags: Fragment;+++[Q6LDS3_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59995.1}; Flags: Fragment;"]
[10605,"'PAIP1'",898,965,917,926.666666666667,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0008494///translation activator activity+++GO:0003723///RNA binding","GO:0048255///mRNA stabilization+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0045727///positive regulation of translation+++GO:0006417///regulation of translation","poly(A) binding protein interacting protein 1","[PAIP1_HUMAN|Reviewed]RecName: Full=Polyadenylate-binding protein-interacting protein 1; Short=PABP-interacting protein 1; Short=PAIP-1; Short=Poly(A)-binding protein-interacting protein 1;+++[A0A024R094_HUMAN|Unreviewed]SubName: Full=Poly(A) binding protein interacting protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW56068.1};+++[A0A1D5RMS4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427410}; Flags: Fragment;+++[D6R9H8_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000422084};+++[D6RD97_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425406}; Flags: Fragment;+++[D6REB4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425084};+++[D6RJ02_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425736}; Flags: Fragment;+++[D6RJF2_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425675}; Flags: Fragment;+++[H0YA44_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000426089}; Flags: Fragment;"]
[10606,"'PAICS'",1300,909,1114,1107.66666666667,"01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites",null,"M00048///Inosine monophosphate biosynthesis, PRPP + glutamine => IMP","R04209///1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase   1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2+++R04591///1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)   ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0045296///cadherin binding+++GO:0043727///5-amino-4-imidazole carboxylate lyase activity+++GO:0003824///catalytic activity+++GO:0004638///phosphoribosylaminoimidazole carboxylase activity+++GO:0016831///carboxy-lyase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity+++GO:0000166///nucleotide binding+++GO:0016829///lyase activity+++GO:0016874///ligase activity+++GO:0005515///protein binding","GO:0009113///purine nucleobase biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0008152///metabolic process+++GO:0006189///'de novo' IMP biosynthetic process","phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase","[PUR6_HUMAN|Reviewed]RecName: Full=Multifunctional protein ADE2; Includes: RecName: Full=Phosphoribosylaminoimidazole-succinocarboxamide synthase; EC=6.3.2.6; AltName: Full=SAICAR synthetase; Includes: RecName: Full=Phosphoribosylaminoimidazole carboxylase; EC=4.1.1.21; AltName: Full=AIR carboxylase; Short=AIRC;+++[A0A024RD93_HUMAN|Unreviewed]SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_c {ECO:0000313|EMBL:EAX05492.1};+++[D6RF62_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424907}; SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_b {ECO:0000313|EMBL:EAX05490.1};+++[E9PBS1_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424053}; Flags: Fragment;"]
[10607,"'TBL3'",731,699,748,726,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0005634///nucleus","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","transducin beta like 3","[TBL3_HUMAN|Reviewed]RecName: Full=Transducin beta-like protein 3; AltName: Full=WD repeat-containing protein SAZD;+++[A0A087WYP7_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000481995};+++[A0JLS5_HUMAN|Unreviewed]SubName: Full=TBL3 protein {ECO:0000313|EMBL:AAH07620.1}; Flags: Fragment;+++[H3BN88_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000454735};+++[J3KNP2_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000331815}; Flags: Fragment;"]
[10608,"'MXD4'",3490,4099,4092,3893.66666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008285///negative regulation of cell proliferation+++GO:0000122///negative regulation of transcription by RNA polymerase II","MAX dimerization protein 4","[MAD4_HUMAN|Reviewed]RecName: Full=Max dimerization protein 4; Short=Max dimerizer 4; AltName: Full=Class C basic helix-loop-helix protein 12; Short=bHLHc12; AltName: Full=Max-associated protein 4; AltName: Full=Max-interacting transcriptional repressor MAD4;+++[D3DVQ5_HUMAN|Unreviewed]SubName: Full=MAX dimerization protein 4, isoform CRA_e {ECO:0000313|EMBL:EAW82535.1};+++[D6RGV1_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000421209};+++[H0Y8Z5_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000422660}; Flags: Fragment;+++[Q7Z2R2_HUMAN|Unreviewed]SubName: Full=MSTP149 {ECO:0000313|EMBL:AAQ13695.1};"]
[10609,"'P3H4'",2127,2624,2370,2373.66666666667,{"$nulls":4},"GO:1902494///catalytic complex+++GO:0000794///condensed nuclear chromosome+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0000795///synaptonemal complex",null,"GO:0032964///collagen biosynthetic process+++GO:0030199///collagen fibril organization+++GO:0046849///bone remodeling+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0007130///synaptonemal complex assembly","prolyl 3-hydroxylase family member 4 (non-enzymatic)","[SC65_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653}; AltName: Full=Leprecan-like protein 4; AltName: Full=Nucleolar autoantigen No55 {ECO:0000303|PubMed:10952778, ECO:0000303|PubMed:8862517}; AltName: Full=Prolyl 3-hydroxylase family member 4 {ECO:0000312|HGNC:HGNC:16946}; AltName: Full=Synaptonemal complex protein SC65 {ECO:0000250|UniProtKB:Q64375}; Flags: Precursor;+++[H0YED7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000435615}; Flags: Fragment;+++[K7EJ03_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000464968}; Flags: Fragment;+++[K7ERA3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000468174}; Flags: Fragment;"]
[10610,"'ST6GALNAC2'",1765,776,1158,1233,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008373///sialyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0016740///transferase activity","GO:0006486///protein glycosylation+++GO:0016266///O-glycan processing+++GO:0006493///protein O-linked glycosylation+++GO:0097503///sialylation+++GO:1990743///protein sialylation","ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2","[SIA7B_HUMAN|Reviewed]RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; EC=2.4.99.3 {ECO:0000269|PubMed:10742600, ECO:0000269|PubMed:29251719}; AltName: Full=GalNAc alpha-2,6-sialyltransferase II; AltName: Full=ST6GalNAc II {ECO:0000303|PubMed:10742600}; Short=ST6GalNAcII {ECO:0000303|PubMed:29251719}; AltName: Full=SThM; AltName: Full=Sialyltransferase 7B; Short=SIAT7-B;+++[A0A024R8M1_HUMAN|Unreviewed]SubName: Full=ST6 (Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, isoform CRA_b {ECO:0000313|EMBL:EAW89418.1};+++[K7EIW2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000464915}; Flags: Fragment;+++[K7EKT8_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000465778};+++[K7EMI2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466513};+++[K7EMM1_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466560}; Flags: Fragment;"]
[10611,"'PDLIM5'",8357,8522.99,6342.85,7740.94666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005913///cell-cell adherens junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0098641///cadherin binding involved in cell-cell adhesion","GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0098609///cell-cell adhesion+++GO:0051963///regulation of synapse assembly+++GO:0061001///regulation of dendritic spine morphogenesis","PDZ and LIM domain 5","[PDLI5_HUMAN|Reviewed]RecName: Full=PDZ and LIM domain protein 5; AltName: Full=Enigma homolog; AltName: Full=Enigma-like PDZ and LIM domains protein;+++[A0A024RDE8_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain 5, isoform CRA_c {ECO:0000313|EMBL:EAX06057.1};+++[A0A0A0MSP3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000398469};+++[A0A0D9SFR4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486834}; Flags: Fragment;+++[A0A0D9SFW3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486938};+++[B7Z481_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54018, highly similar to PDZ and LIM domain protein 5 {ECO:0000313|EMBL:BAH12467.1};+++[B7Z8X5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61541, highly similar to Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 2, mRNA {ECO:0000313|EMBL:BAH14111.1};+++[D6RAA1_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000423009};+++[D6RGG6_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000426379};+++[H0Y8Y3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422528}; Flags: Fragment;+++[H0Y929_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422833}; Flags: Fragment;+++[H0YBI4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000429577}; Flags: Fragment;+++[Q4W5K9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LIM {ECO:0000313|EMBL:AAY40898.1}; Flags: Fragment;"]
[10612,"'TRIM3'",164,204,204,190.666666666667,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005769///early endosome+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0030425///dendrite","GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination","tripartite motif containing 3","[TRIM3_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 3; AltName: Full=Brain-expressed RING finger protein; AltName: Full=RING finger protein 22; AltName: Full=RING finger protein 97;+++[A0A1W2PPI7_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000491359};+++[B7Z5Y8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56028, highly similar to Tripartite motif-containing protein 3 {ECO:0000313|EMBL:BAH13074.1};+++[D3DQT3_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_d {ECO:0000313|EMBL:EAW68713.1}; Flags: Fragment;+++[D3DQT4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_f {ECO:0000313|EMBL:EAW68716.1}; Flags: Fragment;+++[E9PMK8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000433070}; Flags: Fragment;+++[E9PMW5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000437283}; Flags: Fragment;+++[L8EAL7_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM3 {ECO:0000313|EMBL:CCQ43796.1};"]
[10613,"'ERLIN1'",416,376,384,392,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0015485///cholesterol binding","GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0008202///steroid metabolic process+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0032933///SREBP signaling pathway+++GO:0055085///transmembrane transport","ER lipid raft associated 1","[ERLN1_HUMAN|Reviewed]RecName: Full=Erlin-1; AltName: Full=Endoplasmic reticulum lipid raft-associated protein 1; AltName: Full=Protein KE04; AltName: Full=Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; Short=SPFH domain-containing protein 1;+++[B0QZ43_HUMAN|Unreviewed]SubName: Full=Erlin-1 {ECO:0000313|Ensembl:ENSP00000359436}; Flags: Fragment;+++[D3DR65_HUMAN|Unreviewed]SubName: Full=SPFH domain family, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW49847.1};"]
[10614,"'HEXIM1'",596,777,699,690.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0097322///7SK snRNA binding+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0017069///snRNA binding","GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045087///innate immune response+++GO:0007507///heart development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0002376///immune system process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002218///activation of innate immune response","hexamethylene bisacetamide inducible 1","[HEXI1_HUMAN|Reviewed]RecName: Full=Protein HEXIM1; AltName: Full=Cardiac lineage protein 1; AltName: Full=Estrogen down-regulated gene 1 protein; AltName: Full=Hexamethylene bis-acetamide-inducible protein 1; AltName: Full=Menage a quatre protein 1;+++[Q7L853_HUMAN|Unreviewed]SubName: Full=EDG1 {ECO:0000313|EMBL:AAK01993.1}; Flags: Fragment;"]
[10615,"'SPAG5'",20,39,34,31,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0034451///centriolar satellite+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton+++GO:0005694///chromosome+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0000777///condensed chromosome kinetochore+++GO:0005819///spindle+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0007059///chromosome segregation+++GO:0032388///positive regulation of intracellular transport+++GO:0007049///cell cycle+++GO:0000070///mitotic sister chromatid segregation+++GO:0090235///regulation of metaphase plate congression+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0007051///spindle organization+++GO:1905832///positive regulation of spindle assembly+++GO:0071539///protein localization to centrosome","sperm associated antigen 5","[SPAG5_HUMAN|Reviewed]RecName: Full=Sperm-associated antigen 5; AltName: Full=Astrin; AltName: Full=Deepest; AltName: Full=Mitotic spindle-associated protein p126; Short=MAP126;+++[A4FUA2_HUMAN|Unreviewed]SubName: Full=SPAG5 protein {ECO:0000313|EMBL:AAI13056.1}; Flags: Fragment;+++[F5GZT2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000444223}; Flags: Fragment;+++[J3KSV2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000462663};+++[J3KTQ0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000463095}; Flags: Fragment;+++[J3QRL6_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464280}; Flags: Fragment;+++[J3QRV8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464400};+++[J3QS12_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464474}; Flags: Fragment;+++[K7ELC8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466021}; Flags: Fragment;+++[K7ELG0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466061}; Flags: Fragment;"]
[10616,"'RBCK1'",1961,2532,2963,2485.33333333333,"04217///Necroptosis+++04621///NOD-like receptor signaling pathway","H01744///Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis",null,null,"GO:0005829///cytosol+++GO:0071797///LUBAC complex","GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0060546///negative regulation of necroptotic process+++GO:0000209///protein polyubiquitination+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0097039///protein linear polyubiquitination+++GO:0050852///T cell receptor signaling pathway+++GO:0016032///viral process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling","RANBP2-type and C3HC4-type zinc finger containing 1","[HOIL1_HUMAN|Reviewed]RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1; EC=2.3.2.31 {ECO:0000269|PubMed:12629548}; AltName: Full=HBV-associated factor 4; AltName: Full=Heme-oxidized IRP2 ubiquitin ligase 1; Short=HOIL-1; AltName: Full=Hepatitis B virus X-associated protein 4; AltName: Full=RING finger protein 54; AltName: Full=RING-type E3 ubiquitin transferase HOIL-1 {ECO:0000305}; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 3;+++[A6PVJ5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000383106};+++[A6PVJ6_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000417173};+++[A6PVJ7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387799}; Flags: Fragment;+++[A6PVK0_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_b {ECO:0000313|EMBL:EAX10674.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371616};+++[B4DML5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405288}; SubName: Full=cDNA FLJ60704, highly similar to RanBP-type and C3HC4-type zincfinger-containing protein 1 {ECO:0000313|EMBL:BAG59927.1};+++[G3XAG9_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_d {ECO:0000313|EMBL:EAX10676.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371649};+++[H0Y4S7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000393841}; Flags: Fragment;+++[Q5JWR1_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000415080}; Flags: Fragment;"]
[10617,"'STAMBP'",1171,1039,1088,1099.33333333333,"04144///Endocytosis","H01872///Microcephaly-capillary malformation syndrome",null,null,"GO:0005634///nucleus+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0070062///extracellular exosome+++GO:0032154///cleavage furrow+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008237///metallopeptidase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0019904///protein domain specific binding","GO:0046580///negative regulation of Ras protein signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0000281///mitotic cytokinesis+++GO:0007259///JAK-STAT cascade+++GO:0070536///protein K63-linked deubiquitination+++GO:0016579///protein deubiquitination+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0006508///proteolysis","STAM binding protein","[STABP_HUMAN|Reviewed]RecName: Full=STAM-binding protein; EC=3.4.19.-; AltName: Full=Associated molecule with the SH3 domain of STAM; AltName: Full=Endosome-associated ubiquitin isopeptidase;+++[A0A140VK54_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 54 {ECO:0000313|EMBL:AEE61191.1};+++[C9JEK5_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000390921}; Flags: Fragment;+++[C9JK83_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413874}; Flags: Fragment;+++[C9JZ93_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413291}; Flags: Fragment;+++[F5H5B9_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000443502};+++[L8ECD1_HUMAN|Unreviewed]SubName: Full=Alternative protein STAMBP {ECO:0000313|EMBL:CCQ43357.1};"]
[10618,"'TGOLN2'",4490.97,4974,3963,4475.99,"04137///Mitophagy - animal+++00830///Retinol metabolism+++04140///Autophagy - animal",null,null,"R07163///all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductas all-trans-13,14-Dihydroretinol + Acceptor <=> Retinol + Reduced acceptor","GO:0030140///trans-Golgi network transport vesicle+++GO:0005788///endoplasmic reticulum lumen+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0030133///transport vesicle+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0061024///membrane organization+++GO:0044267///cellular protein metabolic process","trans-golgi network protein 2","[TGON2_HUMAN|Reviewed]RecName: Full=Trans-Golgi network integral membrane protein 2; AltName: Full=TGN38 homolog; AltName: Full=TGN46; AltName: Full=TGN48; AltName: Full=Trans-Golgi network protein TGN51; Flags: Precursor;"]
[1062,"'CENPE'",5,2,11,6,null,"H00269///Primary microcephaly (MCPH)",null,null,"GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:0005828///kinetochore microtubule+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0000775///chromosome, centromeric region+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:1990023///mitotic spindle midzone+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0000779///condensed chromosome, centromeric region+++GO:0005874///microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005694///chromosome","GO:0005515///protein binding+++GO:0043515///kinetochore binding+++GO:0016887///ATPase activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0003777///microtubule motor activity","GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0045860///positive regulation of protein kinase activity+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0007275///multicellular organism development+++GO:0099606///microtubule plus-end directed mitotic chromosome migration+++GO:0099607///lateral attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division+++GO:0007059///chromosome segregation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0007049///cell cycle+++GO:0051382///kinetochore assembly+++GO:0007018///microtubule-based movement+++GO:0000278///mitotic cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore","centromere protein E","[CENPE_HUMAN|Reviewed]RecName: Full=Centromere-associated protein E; AltName: Full=Centromere protein E; Short=CENP-E; AltName: Full=Kinesin-7 {ECO:0000303|PubMed:25908662}; AltName: Full=Kinesin-related protein CENPE; Flags: Precursor;+++[A0A087X0P0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000483542};+++[D6RBW0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000423981}; Flags: Fragment;+++[D6RHK2_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000426023}; Flags: Fragment;"]
[10620,"'ARID3B'",129,117,87,111,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II","AT-rich interaction domain 3B","[ARI3B_HUMAN|Reviewed]RecName: Full=AT-rich interactive domain-containing protein 3B; Short=ARID domain-containing protein 3B; AltName: Full=Bright and dead ringer protein; AltName: Full=Bright-like protein;+++[H3BQ92_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 3B {ECO:0000313|Ensembl:ENSP00000455668}; Flags: Fragment;"]
[10621,"'POLR3F'",92,77,79,82.6666666666667,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding","GO:0002376///immune system process+++GO:0045089///positive regulation of innate immune response+++GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III","RNA polymerase III subunit F","[RPC6_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6; Short=RNA polymerase III subunit C6; AltName: Full=DNA-directed RNA polymerase III subunit F; AltName: Full=RNA polymerase III 39 kDa subunit; Short=RPC39;+++[L8EAI3_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3F {ECO:0000313|EMBL:CCQ43358.1};+++[Q05DB8_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763}; Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};"]
[10622,"'POLR3G'",16,6,23,15,"01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++05169///Epstein-Barr virus infection+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA","GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0002376///immune system process+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0045089///positive regulation of innate immune response+++GO:0008283///cell proliferation","RNA polymerase III subunit G","[RPC7_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC7; Short=RNA polymerase III subunit C7; AltName: Full=DNA-directed RNA polymerase III subunit G; AltName: Full=RNA polymerase III 32 kDa apha subunit; Short=RPC32-alpha {ECO:0000303|PubMed:20154270}; AltName: Full=RNA polymerase III 32 kDa subunit; Short=RPC32;+++[A0A024RAM1_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit {ECO:0000256|PIRNR:PIRNR000777};+++[D6R921_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422164}; Flags: Fragment;+++[D6R9U7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422892}; Flags: Fragment;+++[D6REQ0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000424970}; Flags: Fragment;+++[D6RIT0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000427412}; Flags: Fragment;+++[D6RJH6_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000425617};+++[L8E8B4_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3G {ECO:0000313|EMBL:CCQ43359.1};"]
[10623,"'POLR3C'",379,374,367.98,373.66,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++00240///Pyrimidine metabolism+++03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex","GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003697///single-stranded DNA binding","GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0006351///transcription, DNA-templated+++GO:0051607///defense response to virus+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0002376///immune system process+++GO:0006383///transcription by RNA polymerase III","RNA polymerase III subunit C","[RPC3_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC3; Short=RNA polymerase III subunit C3; AltName: Full=DNA-directed RNA polymerase III subunit C; AltName: Full=RNA polymerase III 62 kDa subunit; Short=RPC62;+++[A0A024R4C1_HUMAN|Unreviewed]SubName: Full=Polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b {ECO:0000313|EMBL:EAW71436.1};+++[E9PHH9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000313|Ensembl:ENSP00000358300};+++[Q9BT08_HUMAN|Unreviewed]SubName: Full=POLR3C protein {ECO:0000313|EMBL:AAH04424.1};"]
[10625,"'IVNS1ABP'",5695,7536,5670,6300.33333333333,"05164///Influenza A",{"$nulls":3},"GO:0043025///neuronal cell body+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005743///mitochondrial inner membrane+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity","GO:0042493///response to drug+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0009615///response to virus+++GO:0006383///transcription by RNA polymerase III+++GO:0008380///RNA splicing+++GO:0055114///oxidation-reduction process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033194///response to hydroperoxide+++GO:0014070///response to organic cyclic compound+++GO:0016032///viral process","influenza virus NS1A binding protein",{"$cut":{"chars":32759,"head":"[NS1BP_HUMAN|Reviewed]RecName: Full=Influenza virus NS1A-binding protein; Short=NS1-BP; Short=NS1-binding protein {ECO:0000303|PubMed:9696811}; AltName: Full=Aryl hydrocarbon receptor-associated protein 3 {ECO:0000303|PubMed:16582008}; AltName: Full=Kelch-like protein 39 {ECO:0000303|PubMed:25619834};+++[A0A023I7N5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q5S8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q700_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q7R1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q875_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QC18_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QFT1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QG73_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QHN5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKB4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKQ2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QL98_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QMR7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QR60_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QRY9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QST8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QUI7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QW57_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QWQ3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXG8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXJ5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXT5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QYN1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QZ36_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0"}}]
[10626,"'TRIM16'",227.54,239.64,299.98,255.72,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016605///PML body","GO:0003676///nucleic acid binding+++GO:0032089///NACHT domain binding+++GO:0016740///transferase activity+++GO:0019966///interleukin-1 binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032526///response to retinoic acid+++GO:0060416///response to growth hormone+++GO:0043966///histone H3 acetylation+++GO:0046683///response to organophosphorus+++GO:0045618///positive regulation of keratinocyte differentiation","tripartite motif containing 16","[TRI16_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 16; AltName: Full=Estrogen-responsive B box protein;+++[B3KP96_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31464 fis, clone NT2NE2001337, highly similar to Tripartite motif-containing protein 16 {ECO:0000313|EMBL:BAG51608.1};+++[J3QKY5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463293}; Flags: Fragment;+++[J3QL38_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463360}; Flags: Fragment;+++[J3QLP0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463639};+++[J3QR69_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000464072}; Flags: Fragment;+++[K7EJH2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465169}; Flags: Fragment;+++[K7EL43_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465907}; Flags: Fragment;+++[K7ENN8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000467031}; Flags: Fragment;"]
[10627,"'MYL12A'",4390,5075,5552,5005.66666666667,"04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0016459///myosin complex","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0070527///platelet aggregation","myosin light chain 12A","[ML12A_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12A; AltName: Full=Epididymis secretory protein Li 24; Short=HEL-S-24; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3;+++[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;+++[J3KT92_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000462865}; Flags: Fragment;+++[J3KTJ1_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000463009}; Flags: Fragment;+++[J3QRS3_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000464359}; SubName: Full=Myosin regulatory light chain MRCL3, isoform CRA_b {ECO:0000313|EMBL:EAX01679.1};"]
[10628,"'TXNIP'",399,394,486,426.333333333333,"04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005758///mitochondrial intermembrane space+++GO:0005737///cytoplasm","GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0051782///negative regulation of cell division+++GO:0042127///regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0030216///keratinocyte differentiation+++GO:0006979///response to oxidative stress+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0043086///negative regulation of catalytic activity+++GO:0006606///protein import into nucleus+++GO:0051592///response to calcium ion+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0009612///response to mechanical stimulus+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0042542///response to hydrogen peroxide+++GO:0071228///cellular response to tumor cell","thioredoxin interacting protein","[TXNIP_HUMAN|Reviewed]RecName: Full=Thioredoxin-interacting protein; AltName: Full=Thioredoxin-binding protein 2; AltName: Full=Vitamin D3 up-regulated protein 1;+++[A0A024R4B7_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAW71411.1};+++[B1ALI9_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein {ECO:0000313|EMBL:CAI22352.1}; Flags: Fragment;+++[L8E7V6_HUMAN|Unreviewed]SubName: Full=Alternative protein TXNIP {ECO:0000313|EMBL:CCQ43360.1};"]
[10629,"'TAF6L'",227,229,250,235.333333333333,"05168///Herpes simplex infection+++03022///Basal transcription factors","H01879///Wiedemann-Steiner syndrome",null,null,"GO:0005669///transcription factor TFIID complex+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0046695///SLIK (SAGA-like) complex+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0000118///histone deacetylase complex","GO:0003713///transcription coactivator activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0004402///histone acetyltransferase activity","GO:0043966///histone H3 acetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006338///chromatin remodeling+++GO:0006366///transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006352///DNA-templated transcription, initiation+++GO:0006325///chromatin organization","TATA-box binding protein associated factor 6 like","[TAF6L_HUMAN|Reviewed]RecName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; AltName: Full=PCAF-associated factor 65-alpha; Short=PAF65-alpha;+++[A0A024R5A7_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_a {ECO:0000313|EMBL:EAW74094.1};+++[A8K0D4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78693, highly similar to Homo sapiens TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa (TAF6L), mRNA {ECO:0000313|EMBL:BAF82188.1};+++[B4DVM4_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW74095.1}; SubName: Full=cDNA FLJ57614, highly similar to TAF6-like RNA polymerase IIp300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|EMBL:BAG62736.1};+++[E9PK90_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435443};+++[E9PLV8_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435116}; Flags: Fragment;+++[E9PP94_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000434662}; Flags: Fragment;"]
[1063,"'CENPF'",53,61,43,52.3333333333333,null,"H01814///Stromme syndrome",null,null,"GO:0005930///axoneme+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0045120///pronucleus+++GO:0016363///nuclear matrix+++GO:0000776///kinetochore+++GO:0005635///nuclear envelope+++GO:0097539///ciliary transition fiber+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0030496///midbody+++GO:0005694///chromosome+++GO:0000940///condensed chromosome outer kinetochore+++GO:0000922///spindle pole+++GO:0000777///condensed chromosome kinetochore+++GO:0000775///chromosome, centromeric region","GO:0042803///protein homodimerization activity+++GO:0070840///dynein complex binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding","GO:0021591///ventricular system development+++GO:0001822///kidney development+++GO:0030154///cell differentiation+++GO:0007059///chromosome segregation+++GO:0007517///muscle organ development+++GO:0016202///regulation of striated muscle tissue development+++GO:0051310///metaphase plate congression+++GO:0042493///response to drug+++GO:0000278///mitotic cell cycle+++GO:0051301///cell division+++GO:0015031///protein transport+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0051382///kinetochore assembly+++GO:0071897///DNA biosynthetic process","centromere protein F","[CENPF_HUMAN|Reviewed]RecName: Full=Centromere protein F; Short=CENP-F; AltName: Full=AH antigen; AltName: Full=Kinetochore protein CENPF; AltName: Full=Mitosin; Flags: Precursor;+++[A0A087WTY4_HUMAN|Unreviewed]SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSP00000478221};"]
[10630,"'PDPN'",5479,4472,5008,4986.33333333333,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016323///basolateral plasma membrane+++GO:0071437///invadopodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0031528///microvillus membrane+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0061851///leading edge of lamellipodium+++GO:0001726///ruffle+++GO:0016324///apical plasma membrane+++GO:0031527///filopodium membrane+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0097197///tetraspanin-enriched microdomain+++GO:0045121///membrane raft+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0019956///chemokine binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005372///water transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0051087///chaperone binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity","GO:0044319///wound healing, spreading of cells+++GO:1901731///positive regulation of platelet aggregation+++GO:0001946///lymphangiogenesis+++GO:0060838///lymphatic endothelial cell fate commitment+++GO:0000902///cell morphogenesis+++GO:0003333///amino acid transmembrane transport+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0006833///water transport+++GO:0008360///regulation of cell shape+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:1904328///regulation of myofibroblast contraction+++GO:0008285///negative regulation of cell proliferation+++GO:0051272///positive regulation of cellular component movement+++GO:0015884///folic acid transport+++GO:0030335///positive regulation of cell migration+++GO:0070252///actin-mediated cell contraction+++GO:0030324///lung development+++GO:2000392///regulation of lamellipodium morphogenesis+++GO:0048535///lymph node development+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:1905863///invadopodium organization+++GO:0006865///amino acid transport+++GO:0043066///negative regulation of apoptotic process+++GO:0030168///platelet activation","podoplanin","[PDPN_HUMAN|Reviewed]RecName: Full=Podoplanin {ECO:0000303|Ref.9}; AltName: Full=Aggrus {ECO:0000303|Ref.3}; AltName: Full=Glycoprotein 36; Short=Gp36 {ECO:0000303|PubMed:10393083}; AltName: Full=PA2.26 antigen {ECO:0000303|PubMed:15515019}; AltName: Full=T1-alpha {ECO:0000250|UniProtKB:Q64294}; Short=T1A {ECO:0000250|UniProtKB:Q64294}; Contains: RecName: Full=29kDa cytosolic podoplanin intracellular domain {ECO:0000303|PubMed:24275092}; Short=PICD {ECO:0000303|PubMed:24275092}; Flags: Precursor;+++[D6RH07_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426210};+++[E7ETC6_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000422977};+++[H0Y8Q3_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000421742}; Flags: Fragment;+++[H0YA72_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426302};"]
[10631,"'POSTN'",5343,8179,6254,6592,{"$nulls":4},"GO:0005802///trans-Golgi network+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005615///extracellular space+++GO:0031594///neuromuscular junction+++GO:0062023///collagen-containing extracellular matrix","GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0046872///metal ion binding","GO:0071307///cellular response to vitamin K+++GO:0001666///response to hypoxia+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0009888///tissue development+++GO:0001501///skeletal system development+++GO:1904209///positive regulation of chemokine (C-C motif) ligand 2 secretion+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:0014850///response to muscle activity+++GO:1990138///neuron projection extension+++GO:0032355///response to estradiol+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030198///extracellular matrix organization+++GO:0008593///regulation of Notch signaling pathway+++GO:0042060///wound healing+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0007155///cell adhesion+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1990523///bone regeneration+++GO:0009612///response to mechanical stimulus+++GO:0003073///regulation of systemic arterial blood pressure","periostin","[POSTN_HUMAN|Reviewed]RecName: Full=Periostin; Short=PN; AltName: Full=Osteoblast-specific factor 2; Short=OSF-2; Flags: Precursor;+++[A0A024RDS2_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_c {ECO:0000313|EMBL:EAX08594.1};+++[A0A024RDT5_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_a {ECO:0000313|EMBL:EAX08591.1};+++[B1ALD9_HUMAN|Unreviewed]SubName: Full=Periostin {ECO:0000313|Ensembl:ENSP00000369073};"]
[10632,"'ATP5MG'",1169,1111,1346,1208.66666666667,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane","GO:0015078///proton transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism","GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0015986///ATP synthesis coupled proton transport+++GO:0006811///ion transport","ATP synthase membrane subunit g","[ATP5L_HUMAN|Reviewed]RecName: Full=ATP synthase subunit g, mitochondrial {ECO:0000305}; Short=ATPase subunit g; AltName: Full=ATP synthase membrane subunit g {ECO:0000305};+++[E9PN17_HUMAN|Unreviewed]SubName: Full=ATP synthase membrane subunit g {ECO:0000313|Ensembl:ENSP00000434865};"]
[10633,"'RASL10A'",0,1,4,1.66666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction","RAS like family 10 member A","[RSLAA_HUMAN|Reviewed]RecName: Full=Ras-like protein family member 10A; AltName: Full=Ras-like protein RRP22; AltName: Full=Ras-related protein on chromosome 22; Flags: Precursor;+++[A0A024R1C8_HUMAN|Unreviewed]SubName: Full=RAS-related on chromosome 22, isoform CRA_a {ECO:0000313|EMBL:EAW59797.1};+++[L8E9A0_HUMAN|Unreviewed]SubName: Full=Alternative protein RASL10A {ECO:0000313|EMBL:CCQ42928.1};"]
[10634,"'GAS2L1'",658,796,812,755.333333333333,{"$nulls":4},"GO:0005874///microtubule+++GO:0001725///stress fiber+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0046966///thyroid hormone receptor binding","GO:0001578///microtubule bundle formation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0009267///cellular response to starvation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0010629///negative regulation of gene expression+++GO:0051726///regulation of cell cycle+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest","growth arrest specific 2 like 1","[GA2L1_HUMAN|Reviewed]RecName: Full=GAS2-like protein 1; AltName: Full=GAS2-related protein on chromosome 22; AltName: Full=Growth arrest-specific protein 2-like 1;+++[A0A024R1J4_HUMAN|Unreviewed]SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_b {ECO:0000313|EMBL:EAW59794.1};+++[A0A5E8_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000478343}; SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_a {ECO:0000313|EMBL:EAW59788.1}; SubName: Full=cDNA FLJ16435 fis, clone BRACE3020671, highly similar to GAS2-like protein 1 {ECO:0000313|EMBL:BAG53749.1}; SubName: Full=cDNA FLJ36067 fis, clone TESTI2019308, highly similar to GAR22 PROTEIN {ECO:0000313|EMBL:BAC04150.1};+++[C9JFI0_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000395988}; Flags: Fragment;+++[C9JRR6_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000388645}; Flags: Fragment;"]
[10635,"'RAD51AP1'",9,6,10,8.33333333333333,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin","GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0006310///DNA recombination+++GO:0036297///interstrand cross-link repair+++GO:0071479///cellular response to ionizing radiation+++GO:0000724///double-strand break repair via homologous recombination+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006281///DNA repair","RAD51 associated protein 1","[R51A1_HUMAN|Reviewed]RecName: Full=RAD51-associated protein 1; AltName: Full=RAD51-interacting protein;+++[F5H031_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000438422};+++[F5H1Y0_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000446296};+++[F5H4V6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439925};+++[F5H710_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000442890};+++[H0YFK6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439019}; Flags: Fragment;+++[H0YGT5_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000444769}; Flags: Fragment;"]
[10636,"'RGS14'",304,327,344,325,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016604///nuclear body+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0043197///dendritic spine+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0000922///spindle pole+++GO:0030425///dendrite+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0032794///GTPase activating protein binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030695///GTPase regulator activity+++GO:0005515///protein binding","GO:0060291///long-term synaptic potentiation+++GO:0051301///cell division+++GO:0006913///nucleocytoplasmic transport+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007616///long-term memory+++GO:0008542///visual learning+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0007612///learning+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0000278///mitotic cell cycle+++GO:0007059///chromosome segregation+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0006979///response to oxidative stress+++GO:0050790///regulation of catalytic activity+++GO:0007165///signal transduction+++GO:0010070///zygote asymmetric cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0009968///negative regulation of signal transduction+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0050769///positive regulation of neurogenesis+++GO:0035556///intracellular signal transduction+++GO:0043407///negative regulation of MAP kinase activity","regulator of G protein signaling 14","[RGS14_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 14; Short=RGS14;+++[A0A024R7N4_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein signalling 14, isoform CRA_a {ECO:0000313|EMBL:EAW85013.1};+++[H0Y8W3_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein-signaling 14 {ECO:0000313|Ensembl:ENSP00000422329}; Flags: Fragment;"]
[10638,"'SPHAR'",1.72,0,0,0.573333333333333,{"$nulls":6},"GO:0006260///DNA replication","S-phase response (cyclin related)","[SPHAR_HUMAN|Reviewed]RecName: Full=Protein SPHAR; AltName: Full=S-phase response protein;"]
[10640,"'EXOC5'",736,542,475,584.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0000145///exocyst+++GO:0030496///midbody+++GO:0005737///cytoplasm","GO:0047485///protein N-terminus binding+++GO:0005515///protein binding+++GO:0017160///Ral GTPase binding","GO:0048873///homeostasis of number of cells within a tissue+++GO:1905515///non-motile cilium assembly+++GO:1904019///epithelial cell apoptotic process+++GO:0001736///establishment of planar polarity+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0048278///vesicle docking+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport","exocyst complex component 5","[EXOC5_HUMAN|Reviewed]RecName: Full=Exocyst complex component 5; AltName: Full=Exocyst complex component Sec10; Short=hSec10;+++[A0A0A0MSI8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000389934};+++[F8W9B8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000342100};+++[G3V377_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000451082};+++[G3V4Z7_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000452084}; Flags: Fragment;"]
[10641,"'NPRL2'",277,333,325,311.666666666667,"04150///mTOR signaling pathway",{"$nulls":3},"GO:1990130///GATOR1 complex+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0042802///identical protein binding+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042562///hormone binding+++GO:0005525///GTP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0017046///peptide hormone binding+++GO:0005096///GTPase activator activity+++GO:0000166///nucleotide binding+++GO:0004383///guanylate cyclase activity+++GO:0001653///peptide receptor activity+++GO:0004672///protein kinase activity+++GO:0016829///lyase activity+++GO:0016941///natriuretic peptide receptor activity","GO:2000785///regulation of autophagosome assembly+++GO:0060348///bone development+++GO:0033673///negative regulation of kinase activity+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:1900194///negative regulation of oocyte maturation+++GO:0022414///reproductive process+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0032007///negative regulation of TOR signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0006995///cellular response to nitrogen starvation+++GO:0034198///cellular response to amino acid starvation+++GO:0051447///negative regulation of meiotic cell cycle+++GO:1903779///regulation of cardiac conduction+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0001503///ossification+++GO:0019934///cGMP-mediated signaling+++GO:0010508///positive regulation of autophagy","NPR2 like, GATOR1 complex subunit","[NPRL2_HUMAN|Reviewed]RecName: Full=GATOR complex protein NPRL2 {ECO:0000305}; AltName: Full=Gene 21 protein {ECO:0000303|Ref.1}; Short=G21 protein {ECO:0000303|Ref.1}; AltName: Full=Nitrogen permease regulator 2-like protein {ECO:0000303|PubMed:11085536}; Short=NPR2-like protein {ECO:0000303|PubMed:11085536}; AltName: Full=Tumor suppressor candidate 4 {ECO:0000303|PubMed:18616680};+++[A6NJF2_HUMAN|Unreviewed]SubName: Full=Natriuretic peptide receptor B/guanylate cyclase B (Atrionatriuretic peptide receptor B) variant 3 {ECO:0000313|EMBL:ACA05922.1};+++[F2Z2R8_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000396172};+++[F2Z3D4_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000412779};+++[H7C056_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000393029}; Flags: Fragment;+++[H7C1A1_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000399204}; Flags: Fragment;+++[H7C1X0_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000402902}; Flags: Fragment;"]
[10642,"'IGF2BP1'",972,1089,855,972,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0010494///cytoplasmic stress granule+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003723///RNA binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0003692///left-handed Z-DNA binding+++GO:0042802///identical protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0003729///mRNA binding","GO:0010610///regulation of mRNA stability involved in response to stress+++GO:0097150///neuronal stem cell population maintenance+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0006403///RNA localization+++GO:0002376///immune system process+++GO:0006417///regulation of translation+++GO:0022013///pallium cell proliferation in forebrain+++GO:0017148///negative regulation of translation+++GO:0045087///innate immune response+++GO:0008150///biological_process+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0032479///regulation of type I interferon production+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0043488///regulation of mRNA stability+++GO:0032481///positive regulation of type I interferon production","insulin like growth factor 2 mRNA binding protein 1","[IF2B1_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 1; Short=IGF2 mRNA-binding protein 1; Short=IMP-1; Short=IMP1; AltName: Full=Coding region determinant-binding protein; Short=CRD-BP; AltName: Full=IGF-II mRNA-binding protein 1; AltName: Full=VICKZ family member 1; AltName: Full=Zipcode-binding protein 1; Short=ZBP-1;+++[D3DTW3_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP {ECO:0000313|EMBL:AKM97296.1}; SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94694.1};+++[L8ECD2_HUMAN|Unreviewed]SubName: Full=Alternative protein IGF2BP1 {ECO:0000313|EMBL:CCQ43362.1};"]
[10643,"'IGF2BP3'",596,612,627,611.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0048027///mRNA 5'-UTR binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability+++GO:0051028///mRNA transport+++GO:0017148///negative regulation of translation+++GO:0006412///translation+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0006417///regulation of translation","insulin like growth factor 2 mRNA binding protein 3","[IF2B3_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 3; Short=IGF2 mRNA-binding protein 3; Short=IMP-3; AltName: Full=IGF-II mRNA-binding protein 3; AltName: Full=KH domain-containing protein overexpressed in cancer; Short=hKOC; AltName: Full=VICKZ family member 3;+++[F8WD15_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000395936};"]
[10644,"'IGF2BP2'",1316,1492,1371,1393,null,"H00409///Type II diabetes mellitus",null,null,"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability","insulin like growth factor 2 mRNA binding protein 2","[IF2B2_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 2; Short=IGF2 mRNA-binding protein 2; Short=IMP-2; AltName: Full=Hepatocellular carcinoma autoantigen p62; AltName: Full=IGF-II mRNA-binding protein 2; AltName: Full=VICKZ family member 2;+++[B3FTN5_HUMAN|Unreviewed]SubName: Full=Truncated insulin-like 2 growth factor 2-binding protein 2 {ECO:0000313|EMBL:ACB86628.1};+++[B4DKT5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53054, highly similar to Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|EMBL:BAG59297.1};+++[F8W930_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|Ensembl:ENSP00000410242};"]
[10677,"'AVIL'",7,8,7,7.33333333333333,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0043005///neuron projection+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0060271///cilium assembly+++GO:0051693///actin filament capping+++GO:0007010///cytoskeleton organization+++GO:0010976///positive regulation of neuron projection development+++GO:0007399///nervous system development","advillin","[AVIL_HUMAN|Reviewed]RecName: Full=Advillin; AltName: Full=p92;+++[F8VNY0_HUMAN|Unreviewed]SubName: Full=Advillin {ECO:0000313|Ensembl:ENSP00000450188};+++[F8VVU1_HUMAN|Unreviewed]SubName: Full=Advillin {ECO:0000313|Ensembl:ENSP00000449239}; Flags: Fragment;"]
[106865373,"'WRB-SH3BGR'",35.68,48.63,3.54,29.2833333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane","GO:0017124///SH3 domain binding+++GO:0005070///SH3/SH2 adaptor activity","GO:0065003///protein-containing complex assembly+++GO:0071816///tail-anchored membrane protein insertion into ER membrane","WRB-SH3BGR readthrough","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[MOST1_HUMAN|diamond]RecName: Full=Protein MOST-1;+++[SH3BG_HUMAN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich protein; Short=SH3BGR protein; AltName: Full=21-glutamic acid-rich protein; Short=21-GARP;+++[SH3BG_MOUSE|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich protein; Short=SH3BGR protein;+++[SH3L1_BOVIN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_HUMAN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_MACFA|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_PONAB|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[WRB_BOVIN|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[WRB_HUMAN|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Congenital heart disease 5 protein; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[WRB_PONAB|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN701_HUMAN|diamond]RecName: Full=Zinc finger protein 701;"]
[107282092,"'BOLA2-SMG1P6'",291.98,353.68,310.99,318.883333333333,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0042162///telomeric DNA binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity","GO:0006281///DNA repair+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0032204///regulation of telomere maintenance+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006406///mRNA export from nucleus","BOLA2-SMG1P6 readthrough","[A0A0B4J295_HUMAN|Unreviewed]SubName: Full=BOLA2-SMG1P6 readthrough {ECO:0000313|Ensembl:ENSP00000457792};+++[B4DHK7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53018, highly similar to Serine/threonine-protein kinase SMG1 {ECO:0000313|EMBL:BAG58169.1};+++[H3BTW0_HUMAN|Unreviewed]SubName: Full=BOLA2-SMG1P6 readthrough {ECO:0000313|Ensembl:ENSP00000457350}; Flags: Fragment;+++[H3BVE0_HUMAN|Unreviewed]SubName: Full=BOLA2-SMG1P6 readthrough {ECO:0000313|Ensembl:ENSP00000458075}; Flags: Fragment;"]
[10734,"'STAG3'",31,28.07,24,27.69,"04114///Oocyte meiosis",{"$nulls":3},"GO:0000800///lateral element+++GO:0000795///synaptonemal complex+++GO:0030893///meiotic cohesin complex+++GO:0000794///condensed nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0005634///nucleus+++GO:0001673///male germ cell nucleus+++GO:0000802///transverse filament+++GO:0005615///extracellular space+++GO:0005694///chromosome+++GO:0034991///nuclear meiotic cohesin complex","GO:0003682///chromatin binding+++GO:0005515///protein binding","GO:0051321///meiotic cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0007059///chromosome segregation+++GO:0007049///cell cycle+++GO:0007129///synapsis+++GO:0034502///protein localization to chromosome","stromal antigen 3","[STAG3_HUMAN|Reviewed]RecName: Full=Cohesin subunit SA-3; AltName: Full=SCC3 homolog 3; AltName: Full=Stromal antigen 3; AltName: Full=Stromalin-3;+++[B2RU25_HUMAN|Unreviewed]SubName: Full=Stromal antigen 3 {ECO:0000313|EMBL:AAI40933.1};+++[C9J3T3_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000397067}; Flags: Fragment;+++[C9JTG4_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000409283}; Flags: Fragment;+++[C9JYW5_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000407884}; Flags: Fragment;+++[D6W5U7_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000477973}; SubName: Full=HCG2024106, isoform CRA_c {ECO:0000313|EMBL:EAW76572.1};+++[H0Y4S6_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000393790}; Flags: Fragment;+++[H7C0H6_HUMAN|Unreviewed]SubName: Full=Cohesin subunit SA-3 {ECO:0000313|Ensembl:ENSP00000395039}; Flags: Fragment;"]
[10777,"'ARPP21'",16,16,21,17.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component+++GO:0005737///cytoplasm","GO:0005516///calmodulin binding+++GO:0003676///nucleic acid binding+++GO:0003674///molecular_function","GO:0034605///cellular response to heat+++GO:0008150///biological_process","cAMP regulated phosphoprotein 21","[ARP21_HUMAN|Reviewed]RecName: Full=cAMP-regulated phosphoprotein 21; Short=ARPP-21; AltName: Full=Thymocyte cAMP-regulated phosphoprotein;+++[A8K0T4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78233 {ECO:0000313|EMBL:BAF82338.1};+++[A8K1F3_HUMAN|Unreviewed]SubName: Full=Cyclic AMP-regulated phosphoprotein, 21 kD, isoform CRA_a {ECO:0000313|EMBL:EAW64470.1}; SubName: Full=cDNA FLJ30502 fis, clone BRAWH2000482, highly similar to cAMP-regulated phosphoprotein 21 {ECO:0000313|EMBL:BAG51459.1}; SubName: Full=cDNA FLJ78374 {ECO:0000313|EMBL:BAF82557.1};+++[C9J091_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000412341}; Flags: Fragment;+++[C9J2U3_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000398598}; Flags: Fragment;+++[C9J5R1_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000411644}; Flags: Fragment;+++[C9JD93_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000396324}; Flags: Fragment;+++[C9JI74_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000390169}; Flags: Fragment;+++[C9JQQ6_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000409808}; Flags: Fragment;+++[C9JTF2_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000409331}; Flags: Fragment;+++[C9JTX6_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000413005}; Flags: Fragment;+++[F8WDL2_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000415134};+++[H7C0P9_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000396116}; Flags: Fragment;+++[H7C1B6_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000399482}; Flags: Fragment;+++[H7C2X8_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000408271}; Flags: Fragment;+++[H7C3J7_HUMAN|Unreviewed]SubName: Full=cAMP-regulated phosphoprotein 21 {ECO:0000313|Ensembl:ENSP00000412233}; Flags: Fragment;"]
[10785,"'WDR4'",67,63,73,67.6666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0043527///tRNA methyltransferase complex","GO:0008176///tRNA (guanine-N7-)-methyltransferase activity+++GO:0005515///protein binding","GO:0006400///tRNA modification+++GO:0008033///tRNA processing+++GO:0106004///tRNA (guanine-N7)-methylation+++GO:0036265///RNA (guanine-N7)-methylation+++GO:0030488///tRNA methylation","WD repeat domain 4","[WDR4_HUMAN|Reviewed]RecName: Full=tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056}; AltName: Full=WD repeat-containing protein 4 {ECO:0000255|HAMAP-Rule:MF_03056};"]
[107983998,"'LOC107983998'",34,25,32,30.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006935///chemotaxis+++GO:0010628///positive regulation of gene expression+++GO:0006351///transcription, DNA-templated+++GO:0032757///positive regulation of interleukin-8 production+++GO:0006954///inflammatory response+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0070301///cellular response to hydrogen peroxide+++GO:0002690///positive regulation of leukocyte chemotaxis","uncharacterized LOC107983998","[ZN524_HUMAN|diamond]RecName: Full=Zinc finger protein 524;+++[ZN524_MOUSE|diamond]RecName: Full=Zinc finger protein 524;+++[ZN580_HUMAN|diamond]RecName: Full=Zinc finger protein 580; AltName: Full=LDL-induced EC protein;+++[ZN580_MOUSE|diamond]RecName: Full=Zinc finger protein 580;+++[ZN581_HUMAN|diamond]RecName: Full=Zinc finger protein 581;"]
[107984399,"'LOC107984399'",0,0,1,0.333333333333333,{"$nulls":7},"uncharacterized LOC107984399","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[107984841,"'LOC107984841'",115.51,148.46,104.23,122.733333333333,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005743///mitochondrial inner membrane+++GO:0031966///mitochondrial membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0030425///dendrite+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0042493///response to drug+++GO:0033194///response to hydroperoxide+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0045333///cellular respiration+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0014070///response to organic cyclic compound","uncharacterized LOC107984841","[CIC_HUMAN|diamond]RecName: Full=Protein capicua homolog;+++[CIC_MOUSE|diamond]RecName: Full=Protein capicua homolog;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[NU1M_GORGO|diamond]RecName: Full=NADH-ubiquinone oxidoreductase chain 1; EC=1.6.5.3; AltName: Full=NADH dehydrogenase subunit 1;+++[NU1M_HUMAN|diamond]RecName: Full=NADH-ubiquinone oxidoreductase chain 1; EC=1.6.5.3; AltName: Full=NADH dehydrogenase subunit 1;+++[NU1M_PANTR|diamond]RecName: Full=NADH-ubiquinone oxidoreductase chain 1; EC=1.6.5.3; AltName: Full=NADH dehydrogenase subunit 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[107985657,"'LOC107985657'",1,0,0,0.333333333333333,{"$nulls":7},"uncharacterized LOC107985657","[H2PUX8_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000022518};"]
[107986113,"'LOC107986113'",16.52,38,10,21.5066666666667,{"$nulls":4},"GO:0005886///plasma membrane","GO:0005198///structural molecule activity+++GO:0008270///zinc ion binding+++GO:0003676///nucleic acid binding","GO:0016032///viral process","endogenous retrovirus group K member 7 Gag polyprotein","[GAK24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Gag polyprotein; AltName: Full=HERV-K101 Gag protein; AltName: Full=HERV-K_22q11.21 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Gag polyprotein; AltName: Full=HERV-K(C7) Gag protein; AltName: Full=HERV-K(HML-2.HOM) Gag protein; AltName: Full=HERV-K108 Gag protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Gag polyprotein; AltName: Full=HERV-K(III) Gag protein; AltName: Full=HERV-K102 Gag protein; AltName: Full=HERV-K_1q22 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Gag polyprotein; AltName: Full=HERV-K(C6) Gag protein; AltName: Full=HERV-K109 Gag protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;"]
[107986762,"'LOC107986762'",4,4,3,3.66666666666667,{"$nulls":7},"uncharacterized LOC107986762"]
[107987070,"'LOC107987070'",0.03,0.2,0,0.0766666666666667,{"$nulls":7},"formin-2-like","[A8X0X3_CAEBR|diamond]SubName: Full=Protein CBG06094 {ECO:0000313|EMBL:CAP26283.1};+++[H2P755_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000014194};+++[H2PU68_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000022253};+++[Q6ZQT2_HUMAN|diamond]SubName: Full=cDNA FLJ44869 fis, clone BRAMY2015516 {ECO:0000313|EMBL:BAC87601.1};+++[U3KKM6_FICAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFALP00000015580};"]
[107987373,"'LOC107987373'",2.27,4.3,7,4.52333333333333,"03010///Ribosome",null,"M00178///Ribosome, bacteria+++M00179///Ribosome, archaea",null,"GO:0001650///fibrillar center+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005739///mitochondrion","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation","39S ribosomal protein L23, mitochondrial-like","[A8MYK1_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L23, mitochondrial {ECO:0000313|Ensembl:ENSP00000380465};"]
[10804,"'GJB6'",1,0,0,0.333333333333333,null,"H00648///Ectodermal dysplasia, hidrotic+++H00605///Deafness, autosomal recessive+++H00604///Deafness, autosomal dominant",null,null,"GO:0030054///cell junction+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex",null,"GO:0051602///response to electrical stimulus+++GO:0007605///sensory perception of sound+++GO:0032496///response to lipopolysaccharide+++GO:0008285///negative regulation of cell proliferation+++GO:0007154///cell communication+++GO:0048839///inner ear development+++GO:0042471///ear morphogenesis+++GO:0071333///cellular response to glucose stimulus+++GO:0006915///apoptotic process+++GO:0007568///aging","gap junction protein beta 6","[CXB6_HUMAN|Reviewed]RecName: Full=Gap junction beta-6 protein; AltName: Full=Connexin-30; Short=Cx30;+++[A0A024RDS4_HUMAN|Unreviewed]RecName: Full=Gap junction protein {ECO:0000256|RuleBase:RU000630};+++[A0A2R8Y4J9_HUMAN|Unreviewed]SubName: Full=Gap junction beta-6 protein {ECO:0000313|Ensembl:ENSP00000494122}; Flags: Fragment;+++[A0A2R8Y5T6_HUMAN|Unreviewed]SubName: Full=Gap junction beta-6 protein {ECO:0000313|Ensembl:ENSP00000494720}; Flags: Fragment;+++[A0A2R8Y6N2_HUMAN|Unreviewed]SubName: Full=Gap junction beta-6 protein {ECO:0000313|Ensembl:ENSP00000495437}; Flags: Fragment;+++[A0A2R8YCY0_HUMAN|Unreviewed]SubName: Full=Gap junction beta-6 protein {ECO:0000313|Ensembl:ENSP00000493512}; Flags: Fragment;"]
[10827,"'FAM114A2'",288,257,210,251.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0017076///purine nucleotide binding","GO:0008150///biological_process","family with sequence similarity 114 member A2","[F1142_HUMAN|Reviewed]RecName: Full=Protein FAM114A2;+++[A0A140VKG4_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 81P {ECO:0000313|EMBL:AEE61301.1};+++[B3KTE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38127 fis, clone D6OST2000245 {ECO:0000313|EMBL:BAG53056.1};+++[B4DQT0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56229 {ECO:0000313|EMBL:BAG61042.1};+++[E5RFK2_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000428827}; Flags: Fragment;+++[E5RGF9_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000430186}; Flags: Fragment;+++[E5RH43_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000429919}; Flags: Fragment;+++[E5RHI8_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000429753}; Flags: Fragment;+++[E5RHP2_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000428551}; Flags: Fragment;+++[E5RIK7_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000429403}; Flags: Fragment;+++[E5RK42_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000428941}; Flags: Fragment;+++[E7ESJ7_HUMAN|Unreviewed]SubName: Full=Protein FAM114A2 {ECO:0000313|Ensembl:ENSP00000429088};+++[I6L9D5_HUMAN|Unreviewed]SubName: Full=FAM114A2 protein {ECO:0000313|EMBL:AAH50701.1};"]
[10867,"'TSPAN9'",4155,4175,4198,4176,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0007166///cell surface receptor signaling pathway","tetraspanin 9","[TSN9_HUMAN|Reviewed]RecName: Full=Tetraspanin-9; Short=Tspan-9; AltName: Full=Tetraspan NET-5;+++[A0A1W2PQ04_HUMAN|Unreviewed]SubName: Full=Tetraspanin-9 {ECO:0000313|Ensembl:ENSP00000491848}; Flags: Fragment;+++[B5MD23_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PHL0_HUMAN|Unreviewed]SubName: Full=Tetraspanin-9 {ECO:0000313|Ensembl:ENSP00000412908};"]
[10888,"'GPR83'",40.01,148,87.01,91.6733333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0097730///non-motile cilium+++GO:0016021///integral component of membrane","GO:0004983///neuropeptide Y receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0051384///response to glucocorticoid+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway","G protein-coupled receptor 83","[GPR83_HUMAN|Reviewed]RecName: Full=Probable G-protein coupled receptor 83; AltName: Full=G-protein coupled receptor 72; Flags: Precursor;+++[F5GZ43_HUMAN|Unreviewed]SubName: Full=Probable G-protein-coupled receptor 83 {ECO:0000313|Ensembl:ENSP00000441550};+++[Q6NWR3_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 83 {ECO:0000313|EMBL:AAH67474.1};+++[Q9H011_HUMAN|Unreviewed]SubName: Full=Glucocorticoid induced receptor {ECO:0000313|EMBL:CAC19039.1}; Flags: Fragment;"]
[10911,"'UTS2'",0,1,0,0.333333333333333,"04713///Circadian entrainment+++05168///Herpes simplex infection+++04710///Circadian rhythm","H00688///Familial advanced sleep phase syndrome",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005622///intracellular","GO:0001664///G protein-coupled receptor binding+++GO:0005102///signaling receptor binding+++GO:0051429///corticotropin-releasing hormone receptor binding+++GO:0005179///hormone activity+++GO:0051431///corticotropin-releasing hormone receptor 2 binding+++GO:0042562///hormone binding","GO:0009755///hormone-mediated signaling pathway+++GO:0031669///cellular response to nutrient levels+++GO:0010469///regulation of signaling receptor activity+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0006936///muscle contraction+++GO:0007586///digestion+++GO:0008217///regulation of blood pressure+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0097746///regulation of blood vessel diameter","urotensin 2","[UTS2_HUMAN|Reviewed]RecName: Full=Urotensin-2; AltName: Full=Urotensin II; Short=U-II; Short=UII; Flags: Precursor;+++[A0AVP6_HUMAN|Unreviewed]SubName: Full=UTS2 protein {ECO:0000313|EMBL:AAI26444.1};+++[Q5H8X8_HUMAN|Unreviewed]SubName: Full=Urotensin-2 {ECO:0000313|Ensembl:ENSP00000366738};"]
[10926,"'DBF4'",44,50,44,46,"04110///Cell cycle",{"$nulls":3},"GO:0031431///Dbf4-dependent protein kinase complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0005515///protein binding+++GO:0008047///enzyme activator activity+++GO:0046872///metal ion binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0008270///zinc ion binding+++GO:0019901///protein kinase binding+++GO:0003676///nucleic acid binding","GO:0000082///G1/S transition of mitotic cell cycle+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0043085///positive regulation of catalytic activity+++GO:0006260///DNA replication+++GO:0007049///cell cycle+++GO:0045740///positive regulation of DNA replication","DBF4 zinc finger","[DBF4A_HUMAN|Reviewed]RecName: Full=Protein DBF4 homolog A; AltName: Full=Activator of S phase kinase; AltName: Full=Chiffon homolog A; AltName: Full=DBF4-type zinc finger-containing protein 1;+++[B4DXK0_HUMAN|Unreviewed]SubName: Full=Protein DBF4 homolog A {ECO:0000313|Ensembl:ENSP00000389397}; SubName: Full=cDNA FLJ59266, highly similar to Protein DBF4 homolog {ECO:0000313|EMBL:BAG63412.1};+++[B7Z8C6_HUMAN|Unreviewed]SubName: Full=DBF4 homolog (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW76931.1}; SubName: Full=cDNA FLJ61644, highly similar to Protein DBF4 homolog {ECO:0000313|EMBL:BAH13912.1};+++[F8WF77_HUMAN|Unreviewed]SubName: Full=Protein DBF4 homolog A {ECO:0000313|Ensembl:ENSP00000407116};"]
[10951,"'CBX1'",1030,1218,1121,1123,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00436///Osteopetrosis",null,null,"GO:0005819///spindle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005721///pericentric heterochromatin+++GO:0090734///site of DNA damage+++GO:0000785///chromatin+++GO:0010369///chromocenter+++GO:0001940///male pronucleus+++GO:0005720///nuclear heterochromatin+++GO:0001939///female pronucleus+++GO:0000775///chromosome, centromeric region","GO:1990226///histone methyltransferase binding+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0005515///protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0045892///negative regulation of transcription, DNA-templated","chromobox 1","[CBX1_HUMAN|Reviewed]RecName: Full=Chromobox protein homolog 1; AltName: Full=HP1Hsbeta; AltName: Full=Heterochromatin protein 1 homolog beta; Short=HP1 beta; AltName: Full=Heterochromatin protein p25; AltName: Full=M31; AltName: Full=Modifier 1 protein; AltName: Full=p25beta;+++[B5MD17_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 1 {ECO:0000313|Ensembl:ENSP00000385413}; Flags: Fragment;+++[C9JWS9_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 1 {ECO:0000313|Ensembl:ENSP00000393179}; Flags: Fragment;+++[J3KS05_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 1 {ECO:0000313|Ensembl:ENSP00000462242}; Flags: Fragment;+++[K7ELA4_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 1 {ECO:0000313|Ensembl:ENSP00000465985};+++[Q6IBN6_HUMAN|Unreviewed]SubName: Full=CBX1 protein {ECO:0000313|EMBL:CAG33047.1}; SubName: Full=Chromobox homolog 1 (HP1 beta homolog Drosophila ), isoform CRA_a {ECO:0000313|EMBL:EAW94758.1}; SubName: Full=cDNA, FLJ92997, Homo sapiens chromobox homolog 1 (HP1 beta homolog Drosophila ) (CBX1), mRNA {ECO:0000313|EMBL:BAG35502.1};+++[Q9Y654_HUMAN|Unreviewed]SubName: Full=Heterochromatin-specific nonhistone protein {ECO:0000313|EMBL:AAD21972.1}; Flags: Fragment;"]
[109703458,"'HTD2'",65.32,74.28,45.84,61.8133333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016829///lyase activity+++GO:0018812///3-hydroxyacyl-CoA dehydratase activity","GO:0046949///fatty-acyl-CoA biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process","hydroxyacyl-thioester dehydratase type 2","[HTD2_HUMAN|Reviewed]RecName: Full=Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000303|PubMed:17898086}; Short=HsHTD2 {ECO:0000303|PubMed:17898086}; EC=4.2.1.-; AltName: Full=3-hydroxyacyl-[acyl-carrier-protein] dehydratase {ECO:0000250|UniProtKB:P38790}; Flags: Precursor;+++[A0A087WTC8_HUMAN|Unreviewed]SubName: Full=Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000477762}; Flags: Fragment;+++[A0A087WUW1_HUMAN|Unreviewed]SubName: Full=Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000478964}; Flags: Fragment;+++[A0A087WYB6_HUMAN|Unreviewed]SubName: Full=Hydroxyacyl-thioester dehydratase type 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000481678}; Flags: Fragment;+++[L0R6P0_HUMAN|Unreviewed]SubName: Full=Alternative protein RPP14 {ECO:0000313|EMBL:CCO13807.1}; SubName: Full=Ribonuclease P 14kDa subunit, isoform CRA_a {ECO:0000313|EMBL:EAW65366.1};"]
[10983,"'CCNI'",2132,1887,1636,1885,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005750///mitochondrial respiratory chain complex III+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0070469///respiratory chain+++GO:0005634///nucleus+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex","GO:0020037///heme binding+++GO:0045153///electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:0045155///electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0009055///electron transfer activity+++GO:0004672///protein kinase activity","GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0007088///regulation of mitotic nuclear division+++GO:0033762///response to glucagon+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0051726///regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0006122///mitochondrial electron transport, ubiquinol to cytochrome c+++GO:0007283///spermatogenesis+++GO:0045787///positive regulation of cell cycle+++GO:0000278///mitotic cell cycle+++GO:0055114///oxidation-reduction process","cyclin I","[CCNI_HUMAN|Reviewed]RecName: Full=Cyclin-I;+++[A0A024RDH0_HUMAN|Unreviewed]SubName: Full=Cyclin I, isoform CRA_a {ECO:0000313|EMBL:EAX05810.1};+++[D6RDK3_HUMAN|Unreviewed]SubName: Full=Cyclin-I {ECO:0000313|Ensembl:ENSP00000425360};+++[D6REZ3_HUMAN|Unreviewed]SubName: Full=Cyclin-I {ECO:0000313|Ensembl:ENSP00000421594}; Flags: Fragment;+++[D6RG12_HUMAN|Unreviewed]SubName: Full=Cyclin-I {ECO:0000313|Ensembl:ENSP00000426467}; Flags: Fragment;+++[D6RH01_HUMAN|Unreviewed]SubName: Full=Cyclin-I {ECO:0000313|Ensembl:ENSP00000426235}; Flags: Fragment;+++[H0YA27_HUMAN|Unreviewed]SubName: Full=Cyclin-I {ECO:0000313|Ensembl:ENSP00000425935}; Flags: Fragment;+++[Q6FHH0_HUMAN|Unreviewed]SubName: Full=CCNI protein {ECO:0000313|EMBL:CAG46582.1}; Flags: Fragment;"]
[10994,"'ILVBL'",1161,760,973,964.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003824///catalytic activity+++GO:0030976///thiamine pyrophosphate binding+++GO:0000287///magnesium ion binding+++GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity","GO:0008150///biological_process","ilvB acetolactate synthase like","[ILVBL_HUMAN|Reviewed]RecName: Full=Acetolactate synthase-like protein; EC=2.2.1.-; AltName: Full=IlvB-like protein;+++[E9PJS0_HUMAN|Unreviewed]SubName: Full=Acetolactate synthase-like protein {ECO:0000313|Ensembl:ENSP00000435516}; Flags: Fragment;+++[E9PL44_HUMAN|Unreviewed]SubName: Full=Acetolactate synthase-like protein {ECO:0000313|Ensembl:ENSP00000433355}; Flags: Fragment;+++[E9PNL1_HUMAN|Unreviewed]SubName: Full=Acetolactate synthase-like protein {ECO:0000313|Ensembl:ENSP00000434734};+++[M0QZX5_HUMAN|Unreviewed]SubName: Full=Acetolactate synthase-like protein {ECO:0000313|Ensembl:ENSP00000470834}; Flags: Fragment;+++[M0R026_HUMAN|Unreviewed]SubName: Full=Acetolactate synthase-like protein {ECO:0000313|Ensembl:ENSP00000470942};+++[M0R1B5_HUMAN|Unreviewed]SubName: Full=Acetolactate synthase-like protein {ECO:0000313|Ensembl:ENSP00000471762}; Flags: Fragment;"]
[1103,"'CHAT'",4,1,3,2.66666666666667,"00564///Glycerophospholipid metabolism+++04725///Cholinergic synapse","H00770///Congenital myasthenic syndrome",null,"R01023///Acetyl-CoA:choline O-acetyltransferase   Acetyl-CoA + Choline <=> CoA + Acetylcholine","GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0004102///choline O-acetyltransferase activity","GO:0007269///neurotransmitter secretion+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0042136///neurotransmitter biosynthetic process","choline O-acetyltransferase","[CLAT_HUMAN|Reviewed]RecName: Full=Choline O-acetyltransferase; Short=CHOACTase; Short=ChAT; Short=Choline acetylase; EC=2.3.1.6 {ECO:0000269|PubMed:17144655};+++[D3DX95_HUMAN|Unreviewed]SubName: Full=Choline acetyltransferase, isoform CRA_a {ECO:0000313|EMBL:EAW93089.1};+++[Q6LEN5_HUMAN|Unreviewed]SubName: Full=Choline acetyltransferase {ECO:0000313|EMBL:BAA18945.1}; EC=2.3.1.6 {ECO:0000313|EMBL:BAA18945.1}; Flags: Fragment;+++[Q6LEN6_HUMAN|Unreviewed]SubName: Full=Choline acetyltransferase {ECO:0000313|EMBL:BAA18944.1}; EC=2.3.1.6 {ECO:0000313|EMBL:BAA18944.1}; Flags: Fragment;"]
[1104,"'RCC1'",250,215,227,230.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0032991///protein-containing complex+++GO:0000794///condensed nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0000785///chromatin+++GO:0031965///nuclear membrane","GO:0043199///sulfate binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0042393///histone binding+++GO:0031492///nucleosomal DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0003682///chromatin binding+++GO:0005087///Ran guanyl-nucleotide exchange factor activity+++GO:0031491///nucleosome binding+++GO:0008536///Ran GTPase binding","GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0007052///mitotic spindle organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0051301///cell division+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0016032///viral process+++GO:0051290///protein heterotetramerization+++GO:0051225///spindle assembly","regulator of chromosome condensation 1","[RCC1_HUMAN|Reviewed]RecName: Full=Regulator of chromosome condensation; AltName: Full=Cell cycle regulatory protein; AltName: Full=Chromosome condensation protein 1;+++[A0A0S2Z3I4_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation 1 isoform 3 {ECO:0000313|EMBL:ALQ33434.1}; Flags: Fragment;+++[A0A0S2Z404_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation 1 isoform 2 {ECO:0000313|EMBL:ALQ33433.1}; Flags: Fragment;+++[C9J3R0_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation {ECO:0000313|Ensembl:ENSP00000405258}; Flags: Fragment;+++[C9JMJ4_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation {ECO:0000313|Ensembl:ENSP00000402260}; Flags: Fragment;+++[C9JQZ4_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation {ECO:0000313|Ensembl:ENSP00000394650}; Flags: Fragment;+++[C9JRH2_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation {ECO:0000313|Ensembl:ENSP00000402740}; Flags: Fragment;+++[C9JW69_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation {ECO:0000313|Ensembl:ENSP00000413644}; Flags: Fragment;+++[M0R1Q8_HUMAN|Unreviewed]SubName: Full=Regulator of chromosome condensation {ECO:0000313|Ensembl:ENSP00000472057}; Flags: Fragment;+++[Q5T081_HUMAN|Unreviewed]SubName: Full=CHC1 protein {ECO:0000313|EMBL:CAG28621.1}; SubName: Full=Regulator of chromosome condensation 1 isoform 1 {ECO:0000313|EMBL:ALQ33432.1}; SubName: Full=Regulator of chromosome condensation 1, isoform CRA_b {ECO:0000313|EMBL:EAX07693.1};"]
[11065,"'UBE2C'",10,5,3,6,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex+++GO:0005886///plasma membrane+++GO:0005634///nucleus","GO:0000166///nucleotide binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0005515///protein binding","GO:0010458///exit from mitosis+++GO:0070936///protein K48-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0016567///protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0051301///cell division+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0031536///positive regulation of exit from mitosis+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0007049///cell cycle+++GO:0010994///free ubiquitin chain polymerization","ubiquitin conjugating enzyme E2 C","[UBE2C_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 C; EC=2.3.2.23 {ECO:0000269|PubMed:18485873, ECO:0000269|PubMed:20061386}; AltName: Full=(E3-independent) E2 ubiquitin-conjugating enzyme C; EC=2.3.2.24 {ECO:0000269|PubMed:17588522}; AltName: Full=E2 ubiquitin-conjugating enzyme C; AltName: Full=UbcH10; AltName: Full=Ubiquitin carrier protein C; AltName: Full=Ubiquitin-protein ligase C;+++[A0A087WVK1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 C {ECO:0000313|Ensembl:ENSP00000479486};+++[A0A0A0MSE8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 C {ECO:0000313|Ensembl:ENSP00000385878};+++[K4DI81_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 C {ECO:0000313|Ensembl:ENSP00000243893}; SubName: Full=Ubiquitin-conjugating enzyme E2C, isoform CRA_d {ECO:0000313|EMBL:EAW75808.1};+++[Q5TZN3_HUMAN|Unreviewed]SubName: Full=UBE2C protein {ECO:0000313|EMBL:CAG33269.1}; SubName: Full=Ubiquitin-conjugating enzyme E2C {ECO:0000313|EMBL:AAV38968.1}; SubName: Full=Ubiquitin-conjugating enzyme E2C, isoform CRA_e {ECO:0000313|EMBL:EAW75809.1};"]
[11076,"'TPPP'",588,598,508,564.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0043209///myelin sheath+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0048471///perinuclear region of cytoplasm+++GO:0097427///microtubule bundle+++GO:0005856///cytoskeleton","GO:0015631///tubulin binding+++GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0046785///microtubule polymerization+++GO:0032273///positive regulation of protein polymerization+++GO:0001578///microtubule bundle formation+++GO:0031334///positive regulation of protein complex assembly","tubulin polymerization promoting protein","[TPPP_HUMAN|Reviewed]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=TPPP/p25; AltName: Full=p24; AltName: Full=p25-alpha;+++[Q4L233_HUMAN|Unreviewed]SubName: Full=Brain-specific protein p25 alpha, isoform CRA_b {ECO:0000313|EMBL:EAW51015.1}; SubName: Full=Fibroblast growth factor-2 repression protein-1 {ECO:0000313|EMBL:AAQ96657.1}; SubName: Full=Tubulin polymerization promoting protein {ECO:0000313|EMBL:AAI31507.1}; SubName: Full=cDNA FLJ30358 fis, clone BRACE2007749, highly similar to Tubulin polymerization-promoting protein {ECO:0000313|EMBL:BAG51443.1};"]
[11103,"'KRR1'",285,293,254,277.333333333333,{"$nulls":4},"GO:0005730///nucleolus+++GO:0045171///intercellular bridge+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0032040///small-subunit processome","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis","KRR1, small subunit processome component homolog","[KRR1_HUMAN|Reviewed]RecName: Full=KRR1 small subunit processome component homolog; AltName: Full=HIV-1 Rev-binding protein 2; AltName: Full=KRR-R motif-containing protein 1; AltName: Full=Rev-interacting protein 1; Short=Rip-1;"]
[11117,"'EMILIN1'",26,14,22,20.6666666666667,{"$nulls":4},"GO:0005615///extracellular space+++GO:0034668///integrin alpha4-beta1 complex+++GO:0031012///extracellular matrix+++GO:0005581///collagen trimer+++GO:1990971///EMILIN complex+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0098640///integrin binding involved in cell-matrix adhesion+++GO:0030023///extracellular matrix constituent conferring elasticity","GO:0048251///elastic fiber assembly+++GO:0016477///cell migration+++GO:0010629///negative regulation of gene expression+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0003180///aortic valve morphogenesis+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0016525///negative regulation of angiogenesis+++GO:1905522///negative regulation of macrophage migration+++GO:0030198///extracellular matrix organization+++GO:0050866///negative regulation of cell activation+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0070207///protein homotrimerization+++GO:1904027///negative regulation of collagen fibril organization+++GO:0010628///positive regulation of gene expression+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:1901203///positive regulation of extracellular matrix assembly+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation","elastin microfibril interfacer 1","[EMIL1_HUMAN|Reviewed]RecName: Full=EMILIN-1; AltName: Full=Elastin microfibril interface-located protein 1; Short=Elastin microfibril interfacer 1; Flags: Precursor;+++[A0A0A0MT20_HUMAN|Unreviewed]SubName: Full=EMILIN-1 {ECO:0000313|Ensembl:ENSP00000411201}; Flags: Fragment;"]
[11140,"'CDC37'",2946,3675,4048,3556.33333333333,"04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0101031///chaperone complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:1990565///HSP90-CDC37 chaperone complex","GO:0005515///protein binding+++GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0097110///scaffold protein binding+++GO:0004713///protein tyrosine kinase activity+++GO:0031072///heat shock protein binding+++GO:0019901///protein kinase binding+++GO:0019887///protein kinase regulator activity+++GO:0051879///Hsp90 protein binding+++GO:0019900///kinase binding","GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0060338///regulation of type I interferon-mediated signaling pathway+++GO:0050821///protein stabilization+++GO:0045859///regulation of protein kinase activity+++GO:0051301///cell division+++GO:0038128///ERBB2 signaling pathway+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway+++GO:0006457///protein folding+++GO:0006605///protein targeting","cell division cycle 37","[CDC37_HUMAN|Reviewed]RecName: Full=Hsp90 co-chaperone Cdc37; AltName: Full=Hsp90 chaperone protein kinase-targeting subunit; AltName: Full=p50Cdc37; Contains: RecName: Full=Hsp90 co-chaperone Cdc37, N-terminally processed;+++[A0A024R7B7_HUMAN|Unreviewed]SubName: Full=CDC37 cell division cycle 37 homolog (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW84102.1};+++[K7EIU0_HUMAN|Unreviewed]SubName: Full=Hsp90 co-chaperone Cdc37 {ECO:0000313|Ensembl:ENSP00000464889}; Flags: Fragment;+++[K7EJ06_HUMAN|Unreviewed]SubName: Full=Hsp90 co-chaperone Cdc37 {ECO:0000313|Ensembl:ENSP00000464971};+++[K7EKQ2_HUMAN|Unreviewed]SubName: Full=Hsp90 co-chaperone Cdc37 {ECO:0000313|Ensembl:ENSP00000465724}; Flags: Fragment;+++[K7EL68_HUMAN|Unreviewed]SubName: Full=Hsp90 co-chaperone Cdc37 {ECO:0000313|Ensembl:ENSP00000465941}; Flags: Fragment;+++[K7EQA9_HUMAN|Unreviewed]SubName: Full=Hsp90 co-chaperone Cdc37 {ECO:0000313|Ensembl:ENSP00000467747}; Flags: Fragment;+++[Q6FG59_HUMAN|Unreviewed]SubName: Full=CDC37 protein {ECO:0000313|EMBL:CAG47045.1};"]
[11153,"'FICD'",523,399,384,435.333333333333,null,"H00791///Disseminated superficial actinic porokeratosis (DSAP)",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane","GO:0044603///protein adenylylhydrolase activity+++GO:0016787///hydrolase activity+++GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0030544///Hsp70 protein binding+++GO:0070733///protein adenylyltransferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0051087///chaperone binding+++GO:0042802///identical protein binding","GO:0044602///protein deadenylylation+++GO:0006986///response to unfolded protein+++GO:0034260///negative regulation of GTPase activity+++GO:0034976///response to endoplasmic reticulum stress+++GO:0018117///protein adenylylation+++GO:1903894///regulation of IRE1-mediated unfolded protein response","FIC domain containing","[FICD_HUMAN|Reviewed]RecName: Full=Adenosine monophosphate-protein transferase FICD {ECO:0000305}; EC=2.7.7.n1 {ECO:0000269|PubMed:19362538, ECO:0000269|PubMed:25435325, ECO:0000269|PubMed:25601083}; AltName: Full=AMPylator FICD {ECO:0000305}; AltName: Full=De-AMPylase FICD {ECO:0000250|UniProtKB:A0A061I403}; EC=3.1.4.- {ECO:0000250|UniProtKB:A0A061I403}; AltName: Full=FIC domain-containing protein {ECO:0000303|PubMed:25435325}; AltName: Full=Huntingtin yeast partner E {ECO:0000303|PubMed:25435325, ECO:0000303|PubMed:9700202}; AltName: Full=Huntingtin-interacting protein 13; Short=HIP-13; AltName: Full=Huntingtin-interacting protein E {ECO:0000303|PubMed:25435325, ECO:0000303|PubMed:9700202};+++[A0A024RBM8_HUMAN|Unreviewed]SubName: Full=Huntingtin interacting protein E, isoform CRA_a {ECO:0000313|EMBL:EAW97815.1};+++[F8VZ74_HUMAN|Unreviewed]SubName: Full=Adenosine monophosphate-protein transferase FICD {ECO:0000313|Ensembl:ENSP00000447379};+++[H0YIR6_HUMAN|Unreviewed]SubName: Full=Adenosine monophosphate-protein transferase FICD {ECO:0000313|Ensembl:ENSP00000449989}; Flags: Fragment;+++[J3KP49_HUMAN|Unreviewed]SubName: Full=Adenosine monophosphate-protein transferase FICD {ECO:0000313|Ensembl:ENSP00000354421};"]
[11171,"'STRAP'",1265,1324,1423,1337.33333333333,"03013///RNA transport",null,"M00426///Survival motor neuron (SMN) complex","R01066///2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming) 2-Deoxy-D-ribose 5-phosphate <=> D-Glyceraldehyde 3-phosphate + Acetaldehyde","GO:0005576///extracellular region+++GO:0032797///SMN complex+++GO:0034719///SMN-Sm protein complex+++GO:1904813///ficolin-1-rich granule lumen+++GO:0034774///secretory granule lumen+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0004139///deoxyribose-phosphate aldolase activity","GO:0006098///pentose-phosphate shunt+++GO:0009264///deoxyribonucleotide catabolic process+++GO:0016052///carbohydrate catabolic process+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030277///maintenance of gastrointestinal epithelium+++GO:0060394///negative regulation of pathway-restricted SMAD protein phosphorylation+++GO:0046121///deoxyribonucleoside catabolic process+++GO:0010633///negative regulation of epithelial cell migration+++GO:0046386///deoxyribose phosphate catabolic process+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0000387///spliceosomal snRNP assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0043312///neutrophil degranulation","serine/threonine kinase receptor associated protein","[STRAP_HUMAN|Reviewed]RecName: Full=Serine-threonine kinase receptor-associated protein; AltName: Full=MAP activator with WD repeats; AltName: Full=UNR-interacting protein; AltName: Full=WD-40 repeat protein PT-WD;+++[B0AZV0_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79540, highly similar to Serine-threonine kinase receptor-associatedprotein {ECO:0000313|EMBL:BAF98782.1};"]
[11187,"'PKP3'",5,6,5,5.33333333333333,null,"H00644///Ectodermal dysplasia/skin fragility syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction+++GO:0005913///cell-cell adherens junction+++GO:0001533///cornified envelope+++GO:1990124///messenger ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0030057///desmosome+++GO:0005886///plasma membrane","GO:0045296///cadherin binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0045294///alpha-catenin binding+++GO:0045182///translation regulator activity+++GO:0003723///RNA binding","GO:0006417///regulation of translation+++GO:0002159///desmosome assembly+++GO:0070268///cornification+++GO:1902373///negative regulation of mRNA catabolic process+++GO:0031424///keratinization+++GO:0007155///cell adhesion+++GO:0072659///protein localization to plasma membrane+++GO:0098609///cell-cell adhesion+++GO:0007043///cell-cell junction assembly+++GO:0010628///positive regulation of gene expression","plakophilin 3","[PKP3_HUMAN|Reviewed]RecName: Full=Plakophilin-3;+++[E9PJR7_HUMAN|Unreviewed]SubName: Full=Plakophilin-3 {ECO:0000313|Ensembl:ENSP00000435522}; Flags: Fragment;+++[E9PK71_HUMAN|Unreviewed]SubName: Full=Plakophilin-3 {ECO:0000313|Ensembl:ENSP00000435478}; Flags: Fragment;+++[E9PKC4_HUMAN|Unreviewed]SubName: Full=Plakophilin-3 {ECO:0000313|Ensembl:ENSP00000435383}; Flags: Fragment;+++[E9PQ15_HUMAN|Unreviewed]SubName: Full=Plakophilin-3 {ECO:0000313|Ensembl:ENSP00000434517}; Flags: Fragment;+++[E9PRW6_HUMAN|Unreviewed]SubName: Full=Plakophilin-3 {ECO:0000313|Ensembl:ENSP00000434110}; Flags: Fragment;+++[H0YEY5_HUMAN|Unreviewed]SubName: Full=Plakophilin-3 {ECO:0000313|Ensembl:ENSP00000436847}; Flags: Fragment;"]
[11215,"'AKAP11'",788,697,406,630.333333333333,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008157///protein phosphatase 1 binding+++GO:0051018///protein kinase A binding","GO:0035556///intracellular signal transduction","A-kinase anchoring protein 11","[AKA11_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 11; Short=AKAP-11; AltName: Full=A-kinase anchor protein 220 kDa; Short=AKAP 220; Short=hAKAP220; AltName: Full=Protein kinase A-anchoring protein 11; Short=PRKA11;"]
[112267874,"'LOC112267874'",14,18,16,16,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"translation initiation factor IF-2-like","[PTN2_HUMAN|diamond]RecName: Full=Tyrosine-protein phosphatase non-receptor type 2; EC=3.1.3.48; AltName: Full=T-cell protein-tyrosine phosphatase; Short=TCPTP;+++[PTN2_RAT|diamond]RecName: Full=Tyrosine-protein phosphatase non-receptor type 2; EC=3.1.3.48; AltName: Full=Protein-tyrosine phosphatase PTP-S;+++[PTN6_HUMAN|diamond]RecName: Full=Tyrosine-protein phosphatase non-receptor type 6; EC=3.1.3.48; AltName: Full=Hematopoietic cell protein-tyrosine phosphatase; AltName: Full=Protein-tyrosine phosphatase 1C; Short=PTP-1C; AltName: Full=Protein-tyrosine phosphatase SHP-1; AltName: Full=SH-PTP1;+++[PTN6_MOUSE|diamond]RecName: Full=Tyrosine-protein phosphatase non-receptor type 6; EC=3.1.3.48; AltName: Full=70Z-SHP; AltName: Full=Hematopoietic cell protein-tyrosine phosphatase; AltName: Full=PTPTY-42; AltName: Full=Protein-tyrosine phosphatase 1C; Short=PTP-1C; AltName: Full=SH-PTP1; Short=SHP-1;+++[PTN6_RAT|diamond]RecName: Full=Tyrosine-protein phosphatase non-receptor type 6; EC=3.1.3.48; AltName: Full=Protein-tyrosine phosphatase SHP-1;"]
[112267910,"'LOC112267910'",8,5,3,5.33333333333333,{"$nulls":5},"GO:0005524///ATP binding",null,"NACHT, LRR and PYD domains-containing protein 10-like","[NLRP3_BOVIN|diamond]RecName: Full=NACHT, LRR and PYD domains-containing protein 3;+++[NLRP3_HUMAN|diamond]RecName: Full=NACHT, LRR and PYD domains-containing protein 3; AltName: Full=Angiotensin/vasopressin receptor AII/AVP-like; AltName: Full=Caterpiller protein 1.1; Short=CLR1.1; AltName: Full=Cold-induced autoinflammatory syndrome 1 protein; AltName: Full=Cryopyrin; AltName: Full=PYRIN-containing APAF1-like protein 1;+++[NLRP3_MACMU|diamond]RecName: Full=NACHT, LRR and PYD domains-containing protein 3;+++[NLRP3_MOUSE|diamond]RecName: Full=NACHT, LRR and PYD domains-containing protein 3; AltName: Full=Cold autoinflammatory syndrome 1 protein homolog; AltName: Full=Cryopyrin; AltName: Full=Mast cell maturation-associated-inducible protein 1; AltName: Full=PYRIN-containing APAF1-like protein 1;+++[NLRP3_RAT|diamond]RecName: Full=NACHT, LRR and PYD domains-containing protein 3; AltName: Full=Cold autoinflammatory syndrome 1 protein homolog; AltName: Full=Cryopyrin; AltName: Full=Mast cell maturation-associated-inducible protein 1; AltName: Full=PYRIN-containing APAF1-like protein 1;"]
[112268270,"'LOC112268270'",4,2,7,4.33333333333333,{"$nulls":5},"GO:0008083///growth factor activity",null,"translation initiation factor IF-2-like","[A0A2U4C1V4_TURTR|diamond]SubName: Full=bone morphogenetic protein 7 isoform X1 {ECO:0000313|RefSeq:XP_019799440.1};+++[A0A2U4C239_TURTR|diamond]SubName: Full=bone morphogenetic protein 7 isoform X2 {ECO:0000313|RefSeq:XP_019799441.1};+++[Q8BNL8_MOUSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAC38685.1};"]
[112268271,"'LOC112268271'",4,4,4,4,{"$nulls":4},"GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0035686///sperm fibrous sheath+++GO:0005737///cytoplasm","GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0042803///protein homodimerization activity+++GO:0043295///glutathione binding+++GO:0004364///glutathione transferase activity","GO:0070458///cellular detoxification of nitrogen compound+++GO:0018916///nitrobenzene metabolic process+++GO:0042178///xenobiotic catabolic process+++GO:0043627///response to estrogen+++GO:0006749///glutathione metabolic process","translation initiation factor IF-2-like","[GSTM3_HUMAN|diamond]RecName: Full=Glutathione S-transferase Mu 3; EC=2.5.1.18; AltName: Full=GST class-mu 3; AltName: Full=GSTM3-3; Short=hGSTM3-3;+++[GSTM3_MACFU|diamond]RecName: Full=Glutathione S-transferase Mu 3; EC=2.5.1.18; AltName: Full=GST class-mu 3; AltName: Full=GSTM3-3;+++[GSTM5_MOUSE|diamond]RecName: Full=Glutathione S-transferase Mu 5; EC=2.5.1.18; AltName: Full=Fibrous sheath component 2; Short=Fsc2; AltName: Full=GST class-mu 5;+++[GSTM5_RAT|diamond]RecName: Full=Glutathione S-transferase Mu 5; EC=2.5.1.18; AltName: Full=GST class-mu 5;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;"]
[112268409,"'112268409'",0,1,2,1]
[112399,"'EGLN3'",74,55,56,61.6666666666667,"05200///Pathways in cancer+++05211///Renal cell carcinoma+++04066///HIF-1 signaling pathway","H00236///Congenital polycythemia",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0051213///dioxygenase activity+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0031545///peptidyl-proline 4-dioxygenase activity+++GO:0005506///iron ion binding+++GO:0031418///L-ascorbic acid binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0016491///oxidoreductase activity","GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0006974///cellular response to DNA damage stimulus+++GO:0042127///regulation of cell proliferation+++GO:0018401///peptidyl-proline hydroxylation to 4-hydroxy-L-proline+++GO:0043523///regulation of neuron apoptotic process+++GO:0018126///protein hydroxylation+++GO:0001666///response to hypoxia+++GO:0055114///oxidation-reduction process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006915///apoptotic process","egl-9 family hypoxia inducible factor 3","[EGLN3_HUMAN|Reviewed]RecName: Full=Egl nine homolog 3; EC=1.14.11.29; AltName: Full=HPH-1; AltName: Full=Hypoxia-inducible factor prolyl hydroxylase 3; Short=HIF-PH3; Short=HIF-prolyl hydroxylase 3; Short=HPH-3; AltName: Full=Prolyl hydroxylase domain-containing protein 3; Short=PHD3;+++[A6XP73_HUMAN|Unreviewed]SubName: Full=Egl nine-like protein 3 isoform {ECO:0000313|EMBL:ABM44412.1}; Flags: Fragment;+++[B3KVT0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41356 fis, clone BRCAN2001866, highly similar to Egl nine homolog 3 {ECO:0000313|EMBL:BAG53892.1};+++[F8VR39_HUMAN|Unreviewed]SubName: Full=Egl nine homolog 3 {ECO:0000313|Ensembl:ENSP00000446572};+++[F8W1G2_HUMAN|Unreviewed]SubName: Full=Egl nine homolog 3 {ECO:0000313|Ensembl:ENSP00000447470};+++[G3V3M1_HUMAN|Unreviewed]SubName: Full=Egl nine homolog 3 {ECO:0000313|Ensembl:ENSP00000451316}; Flags: Fragment;+++[Q3T1B0_HUMAN|Unreviewed]SubName: Full=EGLN3 protein {ECO:0000313|EMBL:AAI02031.1};"]
[11255,"'HRH3'",1,0,0,0.333333333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0030425///dendrite+++GO:0098793///presynapse+++GO:0016021///integral component of membrane","GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0004969///histamine receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0014050///negative regulation of glutamate secretion+++GO:0001505///regulation of neurotransmitter levels+++GO:0014063///negative regulation of serotonin secretion+++GO:0007269///neurotransmitter secretion+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0014061///regulation of norepinephrine secretion+++GO:0050890///cognition","histamine receptor H3","[HRH3_HUMAN|Reviewed]RecName: Full=Histamine H3 receptor; Short=H3R; Short=HH3R; AltName: Full=G-protein coupled receptor 97;+++[A0A087WZD3_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor {ECO:0000313|Ensembl:ENSP00000482567};+++[A0A0A0MR48_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor {ECO:0000313|Ensembl:ENSP00000321482}; SubName: Full=Histamine receptor H3, isoform CRA_b {ECO:0000313|EMBL:EAW75382.1};+++[Q548M6_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 1 {ECO:0000313|EMBL:AAL71911.1};+++[Q8NI49_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 6 {ECO:0000313|EMBL:AAM43829.1};+++[Q8NI50_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 5 {ECO:0000313|EMBL:AAM43828.1};+++[Q8WXZ9_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 4 {ECO:0000313|EMBL:AAL71914.1};+++[Q8WY00_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 3 {ECO:0000313|EMBL:AAL71913.1};+++[Q8WY01_HUMAN|Unreviewed]SubName: Full=Histamine H3 receptor isoform 2 {ECO:0000313|EMBL:AAL71912.1};"]
[112724,"'RDH13'",415.99,432.36,436.99,428.446666666667,{"$nulls":4},"GO:0005743///mitochondrial inner membrane","GO:0016491///oxidoreductase activity+++GO:0052650///NADP-retinol dehydrogenase activity","GO:0009644///response to high light intensity+++GO:0055114///oxidation-reduction process+++GO:0010842///retina layer formation+++GO:0042572///retinol metabolic process+++GO:0042462///eye photoreceptor cell development","retinol dehydrogenase 13","[RDH13_HUMAN|Reviewed]RecName: Full=Retinol dehydrogenase 13; EC=1.1.1.-; AltName: Full=Short chain dehydrogenase/reductase family 7C member 3;+++[A0A024R4M8_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 (All-trans and 9-cis), isoform CRA_a {ECO:0000313|EMBL:EAW72322.1};+++[B3KVA3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16300 fis, clone PLACE7000167, highly similar to Retinol dehydrogenase 13 {ECO:0000313|EMBL:BAG53715.1};+++[G8JLA1_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000291892};+++[K7EMY5_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000466708}; Flags: Fragment;+++[K7EQB5_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000467754}; Flags: Fragment;+++[K7ERV1_HUMAN|Unreviewed]SubName: Full=Retinol dehydrogenase 13 {ECO:0000313|Ensembl:ENSP00000468422};"]
[112817,"'HOGA1'",119,125.82,135.26,126.693333333333,"01100///Metabolic pathways+++00330///Arginine and proline metabolism+++00630///Glyoxylate and dicarboxylate metabolism",null,null,"R00471///4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)   (4R)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate+++R00470///4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)   4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate","GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0005759///mitochondrial matrix","GO:0003824///catalytic activity+++GO:0016829///lyase activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0008700///4-hydroxy-2-oxoglutarate aldolase activity","GO:0019470///4-hydroxyproline catabolic process+++GO:0042866///pyruvate biosynthetic process+++GO:0033609///oxalate metabolic process+++GO:0009436///glyoxylate catabolic process+++GO:0046487///glyoxylate metabolic process","4-hydroxy-2-oxoglutarate aldolase 1","[HOGA1_HUMAN|Reviewed]RecName: Full=4-hydroxy-2-oxoglutarate aldolase, mitochondrial; EC=4.1.3.16; AltName: Full=Dihydrodipicolinate synthase-like; Short=DHDPS-like protein; AltName: Full=Probable 2-keto-4-hydroxyglutarate aldolase; Short=Probable KHG-aldolase; AltName: Full=Protein 569272; Flags: Precursor;+++[H7BY76_HUMAN|Unreviewed]SubName: Full=4-hydroxy-2-oxoglutarate aldolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000359676}; Flags: Fragment;"]
[113026,"'PLCD3'",11617,13704,12824,12715,"04919///Thyroid hormone signaling pathway+++04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways+++04933///AGE-RAGE signaling pathway in diabetic complications+++04020///Calcium signaling pathway+++00562///Inositol phosphate metabolism","H01307///Nonsyndromic congenital nail disorder (NDNC)","M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R10952///1-phosphatidyl-1D-myo-inositol-4-phosphate inositolbisphosphohydrolase   1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + 1,2-Diacyl-sn-glycerol+++R03435///1-Phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase   1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol+++R03332///1-Phosphatidyl-D-myo-inositol inositolphosphohydrolase   1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm","GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0046872///metal ion binding","GO:0001525///angiogenesis+++GO:0035556///intracellular signal transduction+++GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0043647///inositol phosphate metabolic process+++GO:0007165///signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0060716///labyrinthine layer blood vessel development","phospholipase C delta 3","[PLCD3_HUMAN|Reviewed]RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; EC=3.1.4.11; AltName: Full=Phosphoinositide phospholipase C-delta-3; AltName: Full=Phospholipase C-delta-3; Short=PLC-delta-3;+++[D3DX63_HUMAN|Unreviewed]RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133}; EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133};+++[F5GXC1_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 {ECO:0000313|Ensembl:ENSP00000440378}; Flags: Fragment;+++[H0YGF8_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 {ECO:0000313|Ensembl:ENSP00000443079}; Flags: Fragment;+++[K7EQF2_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 {ECO:0000313|Ensembl:ENSP00000467800}; Flags: Fragment;"]
[113178,"'SCAMP4'",2507,2960,3199,2888.66666666667,"00062///Fatty acid elongation",null,null,"R01274///palmitoyl-CoA hydrolase Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid","GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0055038///recycling endosome membrane","GO:0003824///catalytic activity+++GO:0046872///metal ion binding+++GO:0008474///palmitoyl-(protein) hydrolase activity","GO:0015031///protein transport","secretory carrier membrane protein 4","[SCAM4_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 4; Short=Secretory carrier membrane protein 4;+++[A0A087WU01_HUMAN|Unreviewed]SubName: Full=Secretory carrier-associated membrane protein 4 {ECO:0000313|Ensembl:ENSP00000478264}; Flags: Fragment;+++[A0A087WVT5_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[A0A087WYP4_HUMAN|Unreviewed]SubName: Full=Secretory carrier-associated membrane protein 4 {ECO:0000313|Ensembl:ENSP00000481989};+++[C9JWM2_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[K7EJJ4_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;"]
[1133,"'CHRM5'",0,1,1,0.666666666666667,"04810///Regulation of actin cytoskeleton+++04080///Neuroactive ligand-receptor interaction+++04020///Calcium signaling pathway+++04725///Cholinergic synapse",{"$nulls":3},"GO:0016020///membrane+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0030425///dendrite+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0016021///integral component of membrane","GO:0016907///G protein-coupled acetylcholine receptor activity+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0030594///neurotransmitter receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007268///chemical synaptic transmission+++GO:0019226///transmission of nerve impulse+++GO:0007197///adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007213///G protein-coupled acetylcholine receptor signaling pathway+++GO:0060304///regulation of phosphatidylinositol dephosphorylation+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0015872///dopamine transport+++GO:0001696///gastric acid secretion+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","cholinergic receptor muscarinic 5","[ACM5_HUMAN|Reviewed]RecName: Full=Muscarinic acetylcholine receptor M5;+++[A0A024R9I2_HUMAN|Unreviewed]RecName: Full=Muscarinic acetylcholine receptor {ECO:0000256|RuleBase:RU361191};+++[H0YKC0_HUMAN|Unreviewed]SubName: Full=Muscarinic acetylcholine receptor M5 {ECO:0000313|Ensembl:ENSP00000452742}; Flags: Fragment;+++[Q6NUM3_HUMAN|Unreviewed]RecName: Full=Muscarinic acetylcholine receptor {ECO:0000256|RuleBase:RU361191};+++[Q8IVW0_HUMAN|Unreviewed]RecName: Full=Muscarinic acetylcholine receptor {ECO:0000256|RuleBase:RU361191};"]
[11340,"'EXOSC8'",64,108,132,101.333333333333,"03018///RNA degradation","H00897///Pontocerebellar hypoplasia","M00391///Exosome, eukaryotes",null,"GO:0000178///exosome (RNase complex)+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0005654///nucleoplasm+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004532///exoribonuclease activity+++GO:0017091///AU-rich element binding","GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process+++GO:0008150///biological_process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034476///U5 snRNA 3'-end processing+++GO:0006364///rRNA processing+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0016075///rRNA catabolic process+++GO:0034473///U1 snRNA 3'-end processing+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0043488///regulation of mRNA stability+++GO:0006401///RNA catabolic process+++GO:0071028///nuclear mRNA surveillance+++GO:0034475///U4 snRNA 3'-end processing+++GO:0006396///RNA processing","exosome component 8","[EXOS8_HUMAN|Reviewed]RecName: Full=Exosome complex component RRP43; AltName: Full=Exosome component 8; AltName: Full=Opa-interacting protein 2; Short=OIP-2; AltName: Full=Ribosomal RNA-processing protein 43; AltName: Full=p9;+++[H7C581_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP43 {ECO:0000313|Ensembl:ENSP00000419203}; Flags: Fragment;+++[H7C5Z2_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP43 {ECO:0000313|Ensembl:ENSP00000239893};"]
[1137,"'CHRNA4'",98,35,41,58,"05033///Nicotine addiction+++04725///Cholinergic synapse+++04080///Neuroactive ligand-receptor interaction","H00807///Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)",null,null,"GO:0030425///dendrite+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0098691///dopaminergic synapse+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005892///acetylcholine-gated channel complex+++GO:0099056///integral component of presynaptic membrane+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0043025///neuronal cell body","GO:0015276///ligand-gated ion channel activity+++GO:0042166///acetylcholine binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:0005515///protein binding+++GO:0005216///ion channel activity+++GO:0015464///acetylcholine receptor activity+++GO:0022848///acetylcholine-gated cation-selective channel activity","GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0007626///locomotory behavior+++GO:0007274///neuromuscular synaptic transmission+++GO:0034220///ion transmembrane transport+++GO:0095500///acetylcholine receptor signaling pathway+++GO:0001666///response to hypoxia+++GO:0035640///exploration behavior+++GO:0006281///DNA repair+++GO:0001508///action potential+++GO:0050877///nervous system process+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0051899///membrane depolarization+++GO:0060080///inhibitory postsynaptic potential+++GO:0007268///chemical synaptic transmission+++GO:0060079///excitatory postsynaptic potential+++GO:0035094///response to nicotine+++GO:0042113///B cell activation+++GO:0007165///signal transduction+++GO:0006816///calcium ion transport+++GO:0035095///behavioral response to nicotine+++GO:0019233///sensory perception of pain+++GO:0014059///regulation of dopamine secretion+++GO:0007271///synaptic transmission, cholinergic+++GO:0050890///cognition+++GO:0006979///response to oxidative stress+++GO:0006811///ion transport+++GO:0042391///regulation of membrane potential+++GO:0007585///respiratory gaseous exchange","cholinergic receptor nicotinic alpha 4 subunit","[ACHA4_HUMAN|Reviewed]RecName: Full=Neuronal acetylcholine receptor subunit alpha-4; Flags: Precursor;+++[A0A0D9SFU6_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-4 {ECO:0000313|Ensembl:ENSP00000486914};+++[B4DK78_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56655 {ECO:0000313|EMBL:BAG59090.1};+++[H0YBH1_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor subunit alpha-4 {ECO:0000313|Ensembl:ENSP00000429513}; Flags: Fragment;+++[Q4VAQ3_HUMAN|Unreviewed]SubName: Full=CHRNA4 protein {ECO:0000313|EMBL:AAH96293.1};+++[Q59FV0_HUMAN|Unreviewed]SubName: Full=Cholinergic receptor, nicotinic, alpha polypeptide 4 variant {ECO:0000313|EMBL:BAD92596.1}; Flags: Fragment;+++[Q5EIU9_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor alpha 4 subunit {ECO:0000313|EMBL:AAW81039.1}; Flags: Fragment;+++[Q5EIV0_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor alpha 4 subunit {ECO:0000313|EMBL:AAW81038.1}; Flags: Fragment;+++[Q5RLM1_HUMAN|Unreviewed]SubName: Full=Neuronal acetylcholine receptor alpha-4 subunit {ECO:0000313|EMBL:AAV66461.1}; Flags: Fragment;"]
[114,"'ADCY8'",15,13,6,11.3333333333333,"04926///Relaxin signaling pathway+++04918///Thyroid hormone synthesis+++04725///Cholinergic synapse+++04923///Regulation of lipolysis in adipocytes+++04971///Gastric acid secretion+++04540///Gap junction+++04928///Parathyroid hormone synthesis, secretion and action+++04915///Estrogen signaling pathway+++04970///Salivary secretion+++04213///Longevity regulating pathway - multiple species+++04022///cGMP-PKG signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04934///Cushing's syndrome+++05414///Dilated cardiomyopathy (DCM)+++04912///GnRH signaling pathway+++04727///GABAergic synapse+++04072///Phospholipase D signaling pathway+++04925///Aldosterone synthesis and secretion+++04024///cAMP signaling pathway+++04270///Vascular smooth muscle contraction+++04913///Ovarian steroidogenesis+++05200///Pathways in cancer+++04261///Adrenergic signaling in cardiomyocytes+++04742///Taste transduction+++05163///Human cytomegalovirus infection+++04927///Cortisol synthesis and secretion+++04020///Calcium signaling pathway+++04723///Retrograde endocannabinoid signaling+++04921///Oxytocin signaling pathway+++04916///Melanogenesis+++04976///Bile secretion+++04611///Platelet activation+++04211///Longevity regulating pathway+++04371///Apelin signaling pathway+++04015///Rap1 signaling pathway+++05032///Morphine addiction+++00230///Purine metabolism+++04720///Long-term potentiation+++04114///Oocyte meiosis+++04062///Chemokine signaling pathway+++04724///Glutamatergic synapse+++04911///Insulin secretion+++01522///Endocrine resistance+++05166///HTLV-I infection+++04713///Circadian entrainment+++04972///Pancreatic secretion+++04714///Thermogenesis+++04914///Progesterone-mediated oocyte maturation",null,"M00695///cAMP signaling","R00089///ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming)   ATP <=> 3',5'-Cyclic AMP + Diphosphate+++R00434///GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)   GTP <=> 3',5'-Cyclic GMP + Diphosphate","GO:0005929///cilium+++GO:0005887///integral component of plasma membrane+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005901///caveola+++GO:0005905///clathrin-coated pit+++GO:0032809///neuronal cell body membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0060076///excitatory synapse+++GO:0016323///basolateral plasma membrane+++GO:0014069///postsynaptic density+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0030424///axon+++GO:0015629///actin cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0045121///membrane raft+++GO:0048786///presynaptic active zone+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0030425///dendrite+++GO:0016020///membrane+++GO:0044853///plasma membrane raft","GO:0046983///protein dimerization activity+++GO:0004016///adenylate cyclase activity+++GO:0051721///protein phosphatase 2A binding+++GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0046872///metal ion binding+++GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity+++GO:0005524///ATP binding+++GO:0016829///lyase activity+++GO:0000166///nucleotide binding+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0005516///calmodulin binding+++GO:0003779///actin binding","GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007613///memory+++GO:0035556///intracellular signal transduction+++GO:1904322///cellular response to forskolin+++GO:0150076///neuroinflammatory response+++GO:0008355///olfactory learning+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0003091///renal water homeostasis+++GO:0051260///protein homooligomerization+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0010255///glucose mediated signaling pathway+++GO:0034199///activation of protein kinase A activity+++GO:0080135///regulation of cellular response to stress+++GO:0042593///glucose homeostasis+++GO:0071315///cellular response to morphine+++GO:0030317///flagellated sperm motility+++GO:0051259///protein complex oligomerization+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:0007611///learning or memory+++GO:1900454///positive regulation of long-term synaptic depression+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:0007626///locomotory behavior+++GO:0007616///long-term memory+++GO:0007340///acrosome reaction+++GO:0007338///single fertilization+++GO:0050896///response to stimulus+++GO:0071277///cellular response to calcium ion+++GO:0007165///signal transduction+++GO:0071377///cellular response to glucagon stimulus+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0031915///positive regulation of synaptic plasticity+++GO:0050804///modulation of chemical synaptic transmission+++GO:0006171///cAMP biosynthetic process+++GO:0038003///opioid receptor signaling pathway+++GO:0071333///cellular response to glucose stimulus+++GO:0007608///sensory perception of smell","adenylate cyclase 8","[ADCY8_HUMAN|Reviewed]RecName: Full=Adenylate cyclase type 8; EC=4.6.1.1; AltName: Full=ATP pyrophosphate-lyase 8; AltName: Full=Adenylate cyclase type VIII {ECO:0000303|PubMed:8076676}; AltName: Full=Adenylyl cyclase 8; Short=AC8; AltName: Full=Ca(2+)/calmodulin-activated adenylyl cyclase;+++[A0A0K0K1K3_HUMAN|Unreviewed]RecName: Full=Adenylate cyclase {ECO:0000256|PIRNR:PIRNR039050}; EC=4.6.1.1 {ECO:0000256|PIRNR:PIRNR039050};+++[C9J969_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000406153}; Flags: Fragment;+++[C9JLX3_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000389799}; Flags: Fragment;+++[C9JYB5_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000401455}; Flags: Fragment;+++[E5RFR2_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 8 {ECO:0000313|Ensembl:ENSP00000428010}; Flags: Fragment;+++[E7EVL1_HUMAN|Unreviewed]RecName: Full=Adenylate cyclase {ECO:0000256|PIRNR:PIRNR039050}; EC=4.6.1.1 {ECO:0000256|PIRNR:PIRNR039050};+++[H7C1A6_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000399275}; Flags: Fragment;+++[H7C1S5_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000402008}; Flags: Fragment;+++[L8E7I7_HUMAN|Unreviewed]SubName: Full=Alternative protein ADCY8 {ECO:0000313|EMBL:CCQ43094.1};+++[Q4F7X0_HUMAN|Unreviewed]RecName: Full=Adenylate cyclase {ECO:0000256|PIRNR:PIRNR039050}; EC=4.6.1.1 {ECO:0000256|PIRNR:PIRNR039050};+++[U3KQ91_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000475652}; Flags: Fragment;+++[U3KQR1_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type 3 {ECO:0000313|Ensembl:ENSP00000476143}; Flags: Fragment;"]
[114757,"'CYGB'",96,77,107,93.3333333333333,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection","GO:0047888///fatty acid peroxidase activity+++GO:0019825///oxygen binding+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0004096///catalase activity+++GO:0008941///nitric oxide dioxygenase activity+++GO:0005515///protein binding+++GO:0004601///peroxidase activity+++GO:0005506///iron ion binding+++GO:0005344///oxygen carrier activity","GO:0015671///oxygen transport+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0098869///cellular oxidant detoxification+++GO:2000490///negative regulation of hepatic stellate cell activation+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0001666///response to hypoxia+++GO:0010764///negative regulation of fibroblast migration+++GO:0006979///response to oxidative stress+++GO:0019395///fatty acid oxidation","cytoglobin","[CYGB_HUMAN|Reviewed]RecName: Full=Cytoglobin; AltName: Full=Histoglobin; Short=HGb; AltName: Full=Stellate cell activation-associated protein;+++[A0A1K0FUB6_HUMAN|Unreviewed]SubName: Full=Globin F {ECO:0000313|EMBL:SAI82141.1};+++[K7EIM9_HUMAN|Unreviewed]SubName: Full=Cytoglobin {ECO:0000313|Ensembl:ENSP00000464817};+++[K7EMC7_HUMAN|Unreviewed]SubName: Full=Cytoglobin {ECO:0000313|Ensembl:ENSP00000466448};"]
[114788,"'CSMD3'",13,7,9,9.66666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0003727///single-stranded RNA binding+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding+++GO:0000166///nucleotide binding","GO:0050773///regulation of dendrite development","CUB and Sushi multiple domains 3","[CSMD3_HUMAN|Reviewed]RecName: Full=CUB and sushi domain-containing protein 3; AltName: Full=CUB and sushi multiple domains protein 3;+++[A5D6Y2_HUMAN|Unreviewed]SubName: Full=CSMD3 protein {ECO:0000313|EMBL:AAI40004.1};+++[H7BXX0_HUMAN|Unreviewed]SubName: Full=CUB and sushi domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000341558}; Flags: Fragment;+++[L8EBH7_HUMAN|Unreviewed]SubName: Full=Alternative protein CSMD3 {ECO:0000313|EMBL:CCQ43938.1};"]
[114879,"'OSBPL5'",254,277,261,264,"04979///Cholesterol metabolism",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0032934///sterol binding+++GO:0008289///lipid binding+++GO:0001786///phosphatidylserine binding+++GO:0015485///cholesterol binding+++GO:0005548///phospholipid transporter activity+++GO:0015248///sterol transporter activity+++GO:0008142///oxysterol binding","GO:0030301///cholesterol transport+++GO:0006869///lipid transport+++GO:0006893///Golgi to plasma membrane transport+++GO:0015914///phospholipid transport+++GO:0008203///cholesterol metabolic process+++GO:0036150///phosphatidylserine acyl-chain remodeling","oxysterol binding protein like 5","[OSBL5_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 5; Short=ORP-5; Short=OSBP-related protein 5; AltName: Full=Oxysterol-binding protein homolog 1 {ECO:0000303|PubMed:12504849};+++[A8KAD5_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[E9PIJ6_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000435812}; Flags: Fragment;+++[E9PJE6_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000433754}; Flags: Fragment;+++[E9PLN3_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000433222}; Flags: Fragment;+++[E9PNH0_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000437141};+++[E9PPQ2_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000436950}; Flags: Fragment;+++[E9PQB4_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000432507}; Flags: Fragment;+++[E9PRA9_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 5 {ECO:0000313|Ensembl:ENSP00000434265};+++[H0YCD7_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;"]
[114898,"'C1QTNF2'",1,1,5,2.33333333333333,{"$nulls":4},"GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding","GO:0051260///protein homooligomerization+++GO:0046321///positive regulation of fatty acid oxidation+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0070208///protein heterotrimerization+++GO:0070206///protein trimerization+++GO:0046326///positive regulation of glucose import+++GO:0000187///activation of MAPK activity","C1q and TNF related 2","[C1QT2_HUMAN|Reviewed]RecName: Full=Complement C1q tumor necrosis factor-related protein 2; Flags: Precursor;+++[L8ECL0_HUMAN|Unreviewed]SubName: Full=Alternative protein C1QTNF2 {ECO:0000313|EMBL:CCQ43752.1};"]
[114926,"'SMIM19'",211,156,212,193,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01574///Familial idiopathic basal ganglia calcification",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0038023///signaling receptor activity+++GO:0005315///inorganic phosphate transmembrane transporter activity+++GO:0001618///virus receptor activity+++GO:0005436///sodium:phosphate symporter activity+++GO:0015321///sodium-dependent phosphate transmembrane transporter activity+++GO:0015319///sodium:inorganic phosphate symporter activity","GO:0006811///ion transport","small integral membrane protein 19","[SMI19_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 19;+++[E5RII4_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 19 {ECO:0000313|Ensembl:ENSP00000430708};+++[E5RKA7_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 19 {ECO:0000313|Ensembl:ENSP00000430387}; Flags: Fragment;"]
[115273,"'RAB42'",41,23,21,28.3333333333333,{"$nulls":4},"GO:0000125///PCAF complex+++GO:0030914///STAGA complex+++GO:0016020///membrane+++GO:0005669///transcription factor TFIID complex+++GO:0033276///transcription factor TFTC complex+++GO:0005654///nucleoplasm+++GO:0000124///SAGA complex+++GO:0005634///nucleus+++GO:0046695///SLIK (SAGA-like) complex","GO:0003677///DNA binding+++GO:0017025///TBP-class protein binding+++GO:0003924///GTPase activity+++GO:0046982///protein heterodimerization activity+++GO:0003713///transcription coactivator activity+++GO:0005525///GTP binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0008134///transcription factor binding","GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0043966///histone H3 acetylation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006352///DNA-templated transcription, initiation+++GO:0006366///transcription by RNA polymerase II","RAB42, member RAS oncogene family","[RAB42_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-42 {ECO:0000305};"]
[115399,"'LRRC56'",162,161,169,164,{"$nulls":4},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0032311///angiogenin-PRI complex+++GO:0005654///nucleoplasm","GO:0008428///ribonuclease inhibitor activity","GO:0006402///mRNA catabolic process+++GO:0045765///regulation of angiogenesis","leucine rich repeat containing 56","[LRC56_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 56;+++[A0A024RCA0_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat containing 56, isoform CRA_b {ECO:0000313|EMBL:EAX02344.1};+++[A0A0G2JLS1_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 56 {ECO:0000313|Ensembl:ENSP00000477831};+++[Q0P6F0_HUMAN|Unreviewed]SubName: Full=LRRC56 protein {ECO:0000313|EMBL:AAH16439.1};"]
[115827,"'RAB3C'",0,3,3,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031982///vesicle+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0098993///anchored component of synaptic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0005768///endosome+++GO:0048471///perinuclear region of cytoplasm","GO:0005525///GTP binding+++GO:0031489///myosin V binding+++GO:0005515///protein binding+++GO:0030742///GTP-dependent protein binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity","GO:0009306///protein secretion+++GO:0017157///regulation of exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0032482///Rab protein signal transduction+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0019882///antigen processing and presentation","RAB3C, member RAS oncogene family","[RAB3C_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-3C;+++[L8E952_HUMAN|Unreviewed]SubName: Full=Alternative protein RAB3C {ECO:0000313|EMBL:CCQ43830.1};"]
[116064,"'LRRC58'",509.87,377.98,292.88,393.576666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"leucine rich repeat containing 58","[LRC58_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 58;"]
[116285,"'ACSM1'",0,2,0,0.666666666666667,"00650///Butanoate metabolism+++01100///Metabolic pathways",null,null,"R01176///Butanoate:CoA ligase (AMP-forming)   ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0070062///extracellular exosome+++GO:0072562///blood microparticle+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005759///mitochondrial matrix","GO:0005524///ATP binding+++GO:0016405///CoA-ligase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003824///catalytic activity+++GO:0004321///fatty-acyl-CoA synthase activity+++GO:0047760///butyrate-CoA ligase activity+++GO:0016874///ligase activity+++GO:0015645///fatty acid ligase activity+++GO:0046872///metal ion binding+++GO:0003996///acyl-CoA ligase activity","GO:0019395///fatty acid oxidation+++GO:0006805///xenobiotic metabolic process+++GO:0006629///lipid metabolic process+++GO:0006633///fatty acid biosynthetic process+++GO:0015980///energy derivation by oxidation of organic compounds+++GO:0006631///fatty acid metabolic process+++GO:0019605///butyrate metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0042632///cholesterol homeostasis+++GO:0018874///benzoate metabolic process","acyl-CoA synthetase medium chain family member 1","[ACSM1_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A synthetase ACSM1, mitochondrial; EC=6.2.1.2; AltName: Full=Acyl-CoA synthetase medium-chain family member 1; AltName: Full=Butyrate--CoA ligase 1; AltName: Full=Butyryl-coenzyme A synthetase 1; AltName: Full=Lipoate-activating enzyme; AltName: Full=Middle-chain acyl-CoA synthetase 1; Flags: Precursor;+++[B2RAP4_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95037, highly similar to Homo sapiens acyl-CoA synthetase medium-chain family member 1 (ACSM1), mRNA {ECO:0000313|EMBL:BAG36941.1};+++[E5RFK0_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A synthetase ACSM1, mitochondrial {ECO:0000313|Ensembl:ENSP00000428830}; Flags: Fragment;+++[H0YAU5_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A synthetase ACSM1, mitochondrial {ECO:0000313|Ensembl:ENSP00000428098}; Flags: Fragment;"]
[116448,"'OLIG1'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048709///oligodendrocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0048663///neuron fate commitment","oligodendrocyte transcription factor 1","[OLIG1_HUMAN|Reviewed]RecName: Full=Oligodendrocyte transcription factor 1; Short=Oligo1; AltName: Full=Class B basic helix-loop-helix protein 6; Short=bHLHb6; AltName: Full=Class E basic helix-loop-helix protein 21; Short=bHLHe21;+++[H7C404_HUMAN|Unreviewed]SubName: Full=Oligodendrocyte transcription factor 1 {ECO:0000313|Ensembl:ENSP00000414840}; Flags: Fragment;"]
[116985,"'ARAP1'",1897,2136,1900,1977.66666666667,"04144///Endocytosis",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032580///Golgi cisterna membrane+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0031702///type 1 angiotensin receptor binding","GO:0051270///regulation of cellular component movement+++GO:0030037///actin filament reorganization involved in cell cycle+++GO:0001921///positive regulation of receptor recycling+++GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0008360///regulation of cell shape+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0051491///positive regulation of filopodium assembly+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0051497///negative regulation of stress fiber assembly","ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1","[ARAP1_HUMAN|Reviewed]RecName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; AltName: Full=Centaurin-delta-2; Short=Cnt-d2;+++[A0A0A0MSJ2_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000390461};+++[A0A2X0SFK3_HUMAN|Unreviewed]SubName: Full=ARAP1 {ECO:0000313|EMBL:SPT35674.1}; Flags: Fragment;+++[B7ZMI2_HUMAN|Unreviewed]SubName: Full=ARAP1 protein {ECO:0000313|EMBL:AAI44563.1};+++[E7EU13_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000392264};+++[F5GWN4_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000399118}; Flags: Fragment;+++[F5GWQ2_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000441741}; Flags: Fragment;+++[F8WBT0_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000411452}; Flags: Fragment;+++[H0YGD1_HUMAN|Unreviewed]SubName: Full=Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000442746}; Flags: Fragment;"]
[117245,"'HRASLS5'",35,12,21,22.6666666666667,{"$nulls":5},"GO:0016746///transferase activity, transferring acyl groups+++GO:0016410///N-acyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding","GO:0070292///N-acylphosphatidylethanolamine metabolic process","HRAS like suppressor family member 5","[HRSL5_HUMAN|Reviewed]RecName: Full=Ca(2+)-independent N-acyltransferase; Short=iNAT; EC=2.3.1.-; AltName: Full=H-rev107-like protein 5; AltName: Full=HRAS-like suppressor 5; Short=HRSL5;+++[B4DY88_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 90 {ECO:0000313|EMBL:AEE61001.1}; SubName: Full=cDNA FLJ60952, highly similar to HRAS-like suppressor 5 {ECO:0000313|EMBL:BAG63650.1};+++[F5H4Q3_HUMAN|Unreviewed]SubName: Full=Ca(2+)-independent N-acyltransferase {ECO:0000313|Ensembl:ENSP00000446016}; Flags: Fragment;+++[H0YGT7_HUMAN|Unreviewed]SubName: Full=Ca(2+)-independent N-acyltransferase {ECO:0000313|Ensembl:ENSP00000444776}; Flags: Fragment;+++[H7BYL7_HUMAN|Unreviewed]SubName: Full=Ca(2+)-independent N-acyltransferase {ECO:0000313|Ensembl:ENSP00000378113}; Flags: Fragment;+++[Q8NE88_HUMAN|Unreviewed]SubName: Full=HRASLS5 protein {ECO:0000313|EMBL:AAH34222.1};"]
[1183,"'CLCN4'",682,379,384,481.666666666667,null,"H02147///X-linked recessive nephrolithiasis with renal failure+++H02142///X-linked recessive hypophosphatemic rickets+++H00480///Non-syndromic X-linked mental retardation+++H00694///Dent disease+++H02149///X-linked hypercalciuric nephrolithiasis+++H00214///Hypophosphatemic rickets+++H02148///Low molecular weight proteinuria with hypercalciuria and nephrocalcinosis",null,null,"GO:0005769///early endosome+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0031901///early endosome membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0005887///integral component of plasma membrane","GO:0005247///voltage-gated chloride channel activity+++GO:0031404///chloride ion binding+++GO:0000166///nucleotide binding+++GO:0015297///antiporter activity+++GO:0005254///chloride channel activity+++GO:0015299///solute:proton antiporter activity+++GO:0005524///ATP binding","GO:0006821///chloride transport+++GO:0034220///ion transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport+++GO:0006811///ion transport","chloride voltage-gated channel 4","[CLCN4_HUMAN|Reviewed]RecName: Full=H(+)/Cl(-) exchange transporter 4; AltName: Full=Chloride channel protein 4; Short=ClC-4; AltName: Full=Chloride transporter ClC-4;+++[E9PFB5_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 4 {ECO:0000313|Ensembl:ENSP00000403064}; Flags: Fragment;+++[G3XAG5_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};+++[Q4G0X3_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};+++[Q75N13_HUMAN|Unreviewed]SubName: Full=Chloride Channel protein 4 {ECO:0000313|EMBL:AAC83175.1}; Flags: Fragment;"]
[1186,"'CLCN7'",3474,3658,3950,3694,null,"H00436///Osteopetrosis",null,null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding+++GO:0005247///voltage-gated chloride channel activity+++GO:0000166///nucleotide binding+++GO:0015297///antiporter activity+++GO:0005524///ATP binding+++GO:0005254///chloride channel activity","GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0009268///response to pH+++GO:0055085///transmembrane transport+++GO:1902476///chloride transmembrane transport","chloride voltage-gated channel 7","[CLCN7_HUMAN|Reviewed]RecName: Full=H(+)/Cl(-) exchange transporter 7; AltName: Full=Chloride channel 7 alpha subunit; AltName: Full=Chloride channel protein 7; Short=ClC-7;+++[H0Y2M6_HUMAN|Unreviewed]SubName: Full=Chloride channel 7, isoform CRA_c {ECO:0000313|EMBL:EAW85655.1}; SubName: Full=H(+)/Cl(-) exchange transporter 7 {ECO:0000313|Ensembl:ENSP00000262318};+++[H3BNG8_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 7 {ECO:0000313|Ensembl:ENSP00000454845}; Flags: Fragment;+++[I3L470_HUMAN|Unreviewed]SubName: Full=H(+)/Cl(-) exchange transporter 7 {ECO:0000313|Ensembl:ENSP00000461009}; Flags: Fragment;+++[Q2VPA2_HUMAN|Unreviewed]SubName: Full=CLCN7 protein {ECO:0000313|EMBL:AAI09197.1}; Flags: Fragment;+++[Q96RY8_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};+++[Q9BRN4_HUMAN|Unreviewed]RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221}; Flags: Fragment;"]
[119016,"'AGAP4'",47.36,45.62,38.25,43.7433333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity","ArfGAP with GTPase domain, ankyrin repeat and PH domain 4","[AGAP4_HUMAN|Reviewed]RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 {ECO:0000312|HGNC:HGNC:23459}; Short=AGAP-4; AltName: Full=Centaurin-gamma-like family member 1 {ECO:0000312|HGNC:HGNC:23459}; AltName: Full=Centaurin-gamma-like family member 5 {ECO:0000312|HGNC:HGNC:23459};+++[A0A087WSV4_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000309985};+++[A0A087WTP8_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000478047};+++[A0A087X0Z1_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000483751};+++[K7ER91_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000468160}; Flags: Fragment;+++[Q86XV2_HUMAN|Unreviewed]SubName: Full=AGAP4 protein {ECO:0000313|EMBL:AAH48341.1}; Flags: Fragment;"]
[119710,"'C11orf74'",387,410,388,395,{"$nulls":4},"GO:0005929///cilium","GO:0046872///metal ion binding+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding+++GO:0003727///single-stranded RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","chromosome 11 open reading frame 74","[CK074_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf74; AltName: Full=Protein HEPIS;+++[A8K468_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76614, highly similar to Homo sapiens HEPIS, mRNA {ECO:0000313|EMBL:BAF83522.1};+++[B4DYW4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51661 {ECO:0000313|EMBL:BAG63876.1};+++[E9PJ48_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf74 {ECO:0000313|Ensembl:ENSP00000435676}; Flags: Fragment;+++[E9PL16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf74 {ECO:0000313|Ensembl:ENSP00000433407}; Flags: Fragment;+++[E9PPH4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf74 {ECO:0000313|Ensembl:ENSP00000432685}; Flags: Fragment;"]
[120526,"'DNAJC24'",319,386,394,366.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005856///cytoskeleton","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0008198///ferrous iron binding+++GO:0001671///ATPase activator activity","GO:0032781///positive regulation of ATPase activity+++GO:0055114///oxidation-reduction process+++GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0061077///chaperone-mediated protein folding","DnaJ heat shock protein family (Hsp40) member C24","[DJC24_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily C member 24 {ECO:0000305}; AltName: Full=CSL-type zinc finger-containing protein 3; AltName: Full=Diphthamide biosynthesis protein 4;+++[A0A0A0MT77_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 24 {ECO:0000313|Ensembl:ENSP00000417548};+++[D3DQZ6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 24 {ECO:0000313|Ensembl:ENSP00000435771}; SubName: Full=Zinc finger, CSL-type containing 3, isoform CRA_c {ECO:0000313|EMBL:EAW68244.1};+++[E9PID3_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 24 {ECO:0000313|Ensembl:ENSP00000432072};+++[E9PRW3_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 24 {ECO:0000313|Ensembl:ENSP00000434114};+++[H0YCV1_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 24 {ECO:0000313|Ensembl:ENSP00000432388}; Flags: Fragment;+++[J3KPT8_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 24 {ECO:0000313|Ensembl:ENSP00000379279}; Flags: Fragment;"]
[1213,"'CLTC'",5849,5466,4037,5117.33333333333,"05100///Bacterial invasion of epithelial cells+++05016///Huntington's disease+++04721///Synaptic vesicle cycle+++04142///Lysosome+++04144///Endocytosis+++04961///Endocrine and other factor-regulated calcium reabsorption",{"$nulls":3},"GO:0031523///Myb complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005819///spindle+++GO:1903561///extracellular vesicle+++GO:0005764///lysosome+++GO:0030117///membrane coat+++GO:0098835///presynaptic endocytic zone membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005856///cytoskeleton+++GO:0005768///endosome+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0030132///clathrin coat of coated pit+++GO:0030659///cytoplasmic vesicle membrane+++GO:1990498///mitotic spindle microtubule+++GO:0030669///clathrin-coated endocytic vesicle membrane+++GO:0030136///clathrin-coated vesicle+++GO:0016020///membrane+++GO:0071439///clathrin complex+++GO:0005737///cytoplasm+++GO:0032588///trans-Golgi network membrane+++GO:0005623///cell+++GO:0072686///mitotic spindle+++GO:0043209///myelin sheath+++GO:0098684///photoreceptor ribbon synapse+++GO:0032991///protein-containing complex+++GO:0030118///clathrin coat+++GO:0005829///cytosol+++GO:0036020///endolysosome membrane+++GO:0005905///clathrin-coated pit+++GO:0030130///clathrin coat of trans-Golgi network vesicle+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0042470///melanosome+++GO:0005886///plasma membrane","GO:0005198///structural molecule activity+++GO:1990381///ubiquitin-specific protease binding+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0019901///protein kinase binding+++GO:0032051///clathrin light chain binding+++GO:0003725///double-stranded RNA binding+++GO:0003723///RNA binding","GO:0034383///low-density lipoprotein particle clearance+++GO:0016192///vesicle-mediated transport+++GO:0033572///transferrin transport+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:0031623///receptor internalization+++GO:0001649///osteoblast differentiation+++GO:0007049///cell cycle+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0006886///intracellular protein transport+++GO:0051301///cell division+++GO:1900126///negative regulation of hyaluronan biosynthetic process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090307///mitotic spindle assembly+++GO:0061024///membrane organization+++GO:0006914///autophagy+++GO:0072583///clathrin-dependent endocytosis+++GO:0045056///transcytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0048268///clathrin coat assembly+++GO:0032802///low-density lipoprotein particle receptor catabolic process+++GO:0000278///mitotic cell cycle+++GO:0060236///regulation of mitotic spindle organization","clathrin heavy chain","[CLH1_HUMAN|Reviewed]RecName: Full=Clathrin heavy chain 1 {ECO:0000303|PubMed:26822784, ECO:0000303|PubMed:29100083}; AltName: Full=Clathrin heavy chain on chromosome 17; Short=CLH-17;+++[A0A087WVQ6_HUMAN|Unreviewed]RecName: Full=Clathrin heavy chain {ECO:0000256|PIRNR:PIRNR002290};+++[J3KRF5_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000461977}; Flags: Fragment;+++[J3KS13_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000462252};+++[J3KSQ2_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000462592}; Flags: Fragment;+++[J3KTN1_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000463068}; Flags: Fragment;+++[J3QL20_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000463336};+++[K7EJJ5_HUMAN|Unreviewed]SubName: Full=Clathrin heavy chain 1 {ECO:0000313|Ensembl:ENSP00000465200}; Flags: Fragment;+++[Q49AL0_HUMAN|Unreviewed]SubName: Full=CLTC protein {ECO:0000313|EMBL:AAH36430.1};"]
[122525,"'C14orf28'",38,41,47,42,{"$nulls":7},"chromosome 14 open reading frame 28","[CN028_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C14orf28; AltName: Full=Dopamine receptor-interacting protein 1;+++[G3V4G8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C14orf28 {ECO:0000313|Ensembl:ENSP00000451791};"]
[122970,"'ACOT4'",31,31,39,33.6666666666667,"01110///Biosynthesis of secondary metabolites+++01040///Biosynthesis of unsaturated fatty acids+++01100///Metabolic pathways+++00062///Fatty acid elongation",null,null,"R08177///Linoleoyl-CoA hydrolase   Linoleoyl-CoA + H2O <=> CoA + Linoleate+++R08174///stearoyl-CoA hydrolase   Stearoyl-CoA + H2O <=> CoA + Octadecanoic acid+++R08182///8,11,14-Eicosatrienoyl-CoA + H2O <=> CoA + (8Z,11Z,14Z)-Icosatrienoic acid+++R08178///(9Z,12Z,15Z)-Octadecatrienoyl-CoA + H2O <=> CoA + (9Z,12Z,15Z)-Octadecatrienoic acid+++R01274///palmitoyl-CoA hydrolase   Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid+++R08183///Arachidonyl-CoA + H2O <=> CoA + Arachidonate+++R08179///(5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA + H2O <=> CoA + (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoic acid+++R09450///long-chain fatty-acyl-CoA hydrolase   Long-chain acyl-CoA + H2O <=> Long-chain fatty acid + CoA+++R08175///Icosanoyl-CoA hydrolase   Eicosanoyl-CoA + H2O <=> CoA + Icosanoic acid+++R08181///gamma-Linolenoyl-CoA + H2O <=> CoA + (6Z,9Z,12Z)-Octadecatrienoic acid+++R08176///oleoyl-CoA hydrolase   Oleoyl-CoA + H2O <=> CoA + (9Z)-Octadecenoic acid+++R08180///(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + H2O <=> CoA + (4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoic acid","GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0005782///peroxisomal matrix","GO:0047617///acyl-CoA hydrolase activity+++GO:0102991///myristoyl-CoA hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0005102///signaling receptor binding+++GO:0004778///succinyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0016790///thiolester hydrolase activity+++GO:0016787///hydrolase activity","GO:0006631///fatty acid metabolic process+++GO:0032788///saturated monocarboxylic acid metabolic process+++GO:0043648///dicarboxylic acid metabolic process+++GO:0006625///protein targeting to peroxisome+++GO:0046459///short-chain fatty acid metabolic process+++GO:0019605///butyrate metabolic process+++GO:0000038///very long-chain fatty acid metabolic process+++GO:0043649///dicarboxylic acid catabolic process+++GO:0001676///long-chain fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process+++GO:0006104///succinyl-CoA metabolic process+++GO:0032789///unsaturated monocarboxylic acid metabolic process","acyl-CoA thioesterase 4","[ACOT4_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A thioesterase 4; Short=Acyl-CoA thioesterase 4; EC=3.1.2.2 {ECO:0000269|PubMed:16940157}; AltName: Full=PTE-2b; AltName: Full=Peroxisomal acyl coenzyme A thioester hydrolase Ib; AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase Ib; Short=PTE-Ib;"]
[123036,"'TC2N'",154,91,81,108.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005575///cellular_component","GO:0003674///molecular_function",null,"tandem C2 domains, nuclear","[TAC2N_HUMAN|Reviewed]RecName: Full=Tandem C2 domains nuclear protein; AltName: Full=Membrane targeting tandem C2 domain-containing protein 1; AltName: Full=Tandem C2 protein in nucleus; Short=Tac2-N;+++[H0YJ73_HUMAN|Unreviewed]SubName: Full=Tandem C2 domains nuclear protein {ECO:0000313|Ensembl:ENSP00000450922}; Flags: Fragment;"]
[1240,"'CMKLR1'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0004950///chemokine receptor activity+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0050848///regulation of calcium-mediated signaling+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0002430///complement receptor mediated signaling pathway+++GO:0070098///chemokine-mediated signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0032695///negative regulation of interleukin-12 production+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0006935///chemotaxis+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0001501///skeletal system development+++GO:0006955///immune response","chemerin chemokine-like receptor 1","[CML1_HUMAN|Reviewed]RecName: Full=Chemokine-like receptor 1; AltName: Full=G-protein coupled receptor ChemR23; AltName: Full=G-protein coupled receptor DEZ;+++[F8VSC8_HUMAN|Unreviewed]SubName: Full=Chemokine-like receptor 1 {ECO:0000313|Ensembl:ENSP00000448362}; Flags: Fragment;+++[F8VYN7_HUMAN|Unreviewed]SubName: Full=Chemokine-like receptor 1 {ECO:0000313|Ensembl:ENSP00000448925}; Flags: Fragment;+++[Q6LEE7_HUMAN|Unreviewed]SubName: Full=Chemokine-like receptor 1 {ECO:0000313|EMBL:AAQ62778.1}; Flags: Fragment;"]
[1241,"'LTB4R'",31.24,52,58.32,47.1866666666667,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0045121///membrane raft","GO:0000166///nucleotide binding+++GO:0001632///leukotriene B4 receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0004966///galanin receptor activity+++GO:0004974///leukotriene receptor activity","GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0006954///inflammatory response+++GO:0007218///neuropeptide signaling pathway+++GO:0006955///immune response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0061737///leukotriene signaling pathway+++GO:0006936///muscle contraction","leukotriene B4 receptor","[LT4R1_HUMAN|Reviewed]RecName: Full=Leukotriene B4 receptor 1; Short=LTB4-R 1; Short=LTB4-R1; AltName: Full=Chemoattractant receptor-like 1; AltName: Full=G-protein coupled receptor 16; AltName: Full=P2Y purinoceptor 7; Short=P2Y7;+++[G3V244_HUMAN|Unreviewed]SubName: Full=Leukotriene B4 receptor 1 {ECO:0000313|Ensembl:ENSP00000450457}; Flags: Fragment;+++[G3V4Q5_HUMAN|Unreviewed]SubName: Full=Leukotriene B4 receptor 1 {ECO:0000313|Ensembl:ENSP00000451929}; Flags: Fragment;"]
[124801,"'LSM12'",1223,1222,1324,1256.33333333333,"01210///2-Oxocarboxylic acid metabolism+++04140///Autophagy - animal+++01230///Biosynthesis of amino acids+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++04137///Mitophagy - animal+++00220///Arginine biosynthesis","H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H01032///N-acetylglutamate synthase (NAGS) deficiency",null,"R00259///acetyl-CoA:L-glutamate N-acetyltransferase Acetyl-CoA + L-Glutamate <=> CoA + N-Acetyl-L-glutamate","GO:0016021///integral component of membrane",null,"GO:0016070///RNA metabolic process","LSM12 homolog","[LSM12_HUMAN|Reviewed]RecName: Full=Protein LSM12 homolog;+++[K7ELG9_HUMAN|Unreviewed]SubName: Full=Protein LSM12 homolog {ECO:0000313|Ensembl:ENSP00000466074};"]
[124912,"'SPACA3'",0,0,2,0.666666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0043159///acrosomal matrix+++GO:0001669///acrosomal vesicle+++GO:0016021///integral component of membrane+++GO:0030141///secretory granule+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle+++GO:0002080///acrosomal membrane","GO:0003796///lysozyme activity+++GO:0005515///protein binding","GO:0007342///fusion of sperm to egg plasma membrane involved in single fertilization+++GO:0050830///defense response to Gram-positive bacterium+++GO:0042117///monocyte activation+++GO:0050766///positive regulation of phagocytosis+++GO:0035036///sperm-egg recognition+++GO:0043032///positive regulation of macrophage activation+++GO:0009566///fertilization+++GO:0050829///defense response to Gram-negative bacterium","sperm acrosome associated 3","[SACA3_HUMAN|Reviewed]RecName: Full=Sperm acrosome membrane-associated protein 3; AltName: Full=Cancer/testis antigen 54; Short=CT54; AltName: Full=Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17; AltName: Full=Lysozyme-like protein 3; AltName: Full=Sperm lysozyme-like protein 1; AltName: Full=Sperm protein reactive with antisperm antibodies; Short=Sperm protein reactive with ASA; Contains: RecName: Full=Sperm acrosome membrane-associated protein 3, membrane form; Contains: RecName: Full=Sperm acrosome membrane-associated protein 3, processed form;+++[A0A080YUZ7_HUMAN|Unreviewed]SubName: Full=Lysozyme C {ECO:0000313|EMBL:CDM98737.1}; SubName: Full=Sperm acrosome associated 3, isoform CRA_a {ECO:0000313|EMBL:EAW80217.1};+++[E9PF91_HUMAN|Unreviewed]SubName: Full=Sperm acrosome membrane-associated protein 3 {ECO:0000313|Ensembl:ENSP00000378134};+++[Q05C28_HUMAN|Unreviewed]SubName: Full=SPACA3 protein {ECO:0000313|EMBL:AAH29867.1};"]
[124995,"'MRPL10'",544,625,650,606.333333333333,"03010///Ribosome",null,"M00178///Ribosome, bacteria+++M00179///Ribosome, archaea",null,"GO:0005743///mitochondrial inner membrane+++GO:0015934///large ribosomal subunit+++GO:0005840///ribosome+++GO:0005762///mitochondrial large ribosomal subunit+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding","GO:0006412///translation+++GO:0042254///ribosome biogenesis+++GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination","mitochondrial ribosomal protein L10","[RM10_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L10, mitochondrial; Short=L10mt; Short=MRP-L10; AltName: Full=39S ribosomal protein L8, mitochondrial; Short=L8mt; Short=MRP-L8; AltName: Full=Mitochondrial large ribosomal subunit protein uL10m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[B4DEH0_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein L10, isoform CRA_d {ECO:0000313|EMBL:EAW94799.1}; SubName: Full=cDNA FLJ55192, highly similar to Homo sapiens mitochondrial ribosomal protein L10 (MRPL10), mRNA {ECO:0000313|EMBL:BAG57081.1};+++[F2Z2K7_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L10, mitochondrial {ECO:0000313|Ensembl:ENSP00000390624};"]
[126014,"'OSCAR'",2,0,2,1.33333333333333,"04380///Osteoclast differentiation",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0035580///specific granule lumen+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:1904724///tertiary granule lumen+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0038064///collagen receptor activity","GO:0038094///Fc-gamma receptor signaling pathway+++GO:0072674///multinuclear osteoclast differentiation+++GO:0050776///regulation of immune response+++GO:0045780///positive regulation of bone resorption+++GO:0032623///interleukin-2 production+++GO:0043312///neutrophil degranulation+++GO:0038065///collagen-activated signaling pathway+++GO:0030316///osteoclast differentiation","osteoclast associated, immunoglobulin-like receptor","[OSCAR_HUMAN|Reviewed]RecName: Full=Osteoclast-associated immunoglobulin-like receptor; Short=Osteoclast-associated receptor; Short=hOSCAR; AltName: Full=Polymeric immunoglobulin receptor 3; Short=PIgR-3; Short=PIgR3; Short=Poly-Ig receptor 3; Flags: Precursor;+++[A0A087WV17_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000479089};+++[A0A087X0P3_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000483558};+++[A0A087X1R2_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000484401};+++[A0A0A0MR14_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000304523};+++[A0A0A0MRF2_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000351145};+++[A0A0G2JMM7_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000479593};+++[A0A0G2JNK2_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000481561};+++[A8MWV3_HUMAN|Unreviewed]SubName: Full=Osteoclast-associated immunoglobulin-like receptor {ECO:0000313|Ensembl:ENSP00000375640};"]
[126129,"'CPT1C'",770,984,969,907.666666666667,"03320///PPAR signaling pathway+++04920///Adipocytokine signaling pathway+++01212///Fatty acid metabolism+++04714///Thermogenesis+++04922///Glucagon signaling pathway+++04152///AMPK signaling pathway+++00071///Fatty acid degradation","H00266///Hereditary spastic paraplegia (SPG)",null,"R01923///palmitoyl-CoA:L-carnitine O-palmitoyltransferase   Palmitoyl-CoA + L-Carnitine <=> CoA + L-Palmitoylcarnitine","GO:0005741///mitochondrial outer membrane+++GO:0042995///cell projection+++GO:0030424///axon+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0030425///dendrite+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030054///cell junction+++GO:0005739///mitochondrion+++GO:0098794///postsynapse+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0032281///AMPA glutamate receptor complex+++GO:0005783///endoplasmic reticulum","GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0004095///carnitine O-palmitoyltransferase activity+++GO:0005515///protein binding","GO:0006631///fatty acid metabolic process+++GO:0015909///long-chain fatty acid transport+++GO:0009437///carnitine metabolic process+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0006635///fatty acid beta-oxidation+++GO:0006629///lipid metabolic process","carnitine palmitoyltransferase 1C","[CPT1C_HUMAN|Reviewed]RecName: Full=Carnitine O-palmitoyltransferase 1, brain isoform; Short=CPT1-B; EC=2.3.1.21; AltName: Full=CPT IC; AltName: Full=Carnitine O-palmitoyltransferase I, brain isoform; Short=CPTI-B; AltName: Full=Carnitine palmitoyltransferase 1C;+++[A0A024QZE3_HUMAN|Unreviewed]SubName: Full=Carnitine palmitoyltransferase 1C, isoform CRA_b {ECO:0000313|EMBL:EAW52528.1};+++[A0A024QZI3_HUMAN|Unreviewed]SubName: Full=Carnitine palmitoyltransferase 1C, isoform CRA_a {ECO:0000313|EMBL:EAW52530.1};+++[B3KU49_HUMAN|Unreviewed]SubName: Full=Carnitine palmitoyltransferase 1C, isoform CRA_d {ECO:0000313|EMBL:EAW52526.1}; SubName: Full=cDNA FLJ39197 fis, clone OCBBF2005077, highly similar to Carnitine O-palmitoyltransferase I, brain isoform {ECO:0000313|EMBL:BAG53311.1}; Flags: Fragment;+++[M0QZ13_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000470221}; Flags: Fragment;+++[M0R0D3_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000471160}; SubName: Full=Carnitine palmitoyltransferase 1C, isoform CRA_f {ECO:0000313|EMBL:EAW52529.1};+++[M0R115_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000471579}; Flags: Fragment;+++[M0R1F9_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000471841}; Flags: Fragment;+++[M0R2B9_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000472453}; Flags: Fragment;+++[M0R2H6_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000472579}; Flags: Fragment;+++[M0R2V3_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000472828}; Flags: Fragment;+++[M0R399_HUMAN|Unreviewed]SubName: Full=Carnitine O-palmitoyltransferase 1, brain isoform {ECO:0000313|Ensembl:ENSP00000473082}; SubName: Full=Carnitine palmitoyltransferase 1C, isoform CRA_h {ECO:0000313|EMBL:EAW52532.1};"]
[126382,"'NR2C2AP'",80,92,81,84.3333333333333,"05340///Primary immunodeficiency+++05152///Tuberculosis+++04612///Antigen processing and presentation","H00985///Bare lymphocyte syndrome (BLS) type2+++H00093///Combined immunodeficiencies (CIDs)",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0006367///transcription initiation from RNA polymerase II promoter","nuclear receptor 2C2 associated protein","[NR2CA_HUMAN|Reviewed]RecName: Full=Nuclear receptor 2C2-associated protein; AltName: Full=TR4 orphan receptor-associated 16 kDa protein;+++[F5H0B6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor 2C2-associated protein {ECO:0000313|Ensembl:ENSP00000438092};+++[U3KQ53_HUMAN|Unreviewed]SubName: Full=Nuclear receptor 2C2-associated protein {ECO:0000313|Ensembl:ENSP00000475559};+++[U3KQN8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor 2C2-associated protein {ECO:0000313|Ensembl:ENSP00000476087}; Flags: Fragment;"]
[126526,"'C19orf47'",367.4,319.19,408,364.863333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"chromosome 19 open reading frame 47","[CS047_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf47;+++[A0A2R8Y6U9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000495586}; Flags: Fragment;+++[J3QKY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000463294};+++[J3QKZ5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000463305}; Flags: Fragment;+++[J3QS16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000464478}; Flags: Fragment;+++[J3QS80_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000464567}; Flags: Fragment;+++[J9JIE4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000350556}; Flags: Fragment;"]
[127003,"'C1orf194'",4,2,0,2,{"$nulls":7},"chromosome 1 open reading frame 194","[CA194_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C1orf194;+++[B1ALJ5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf194 {ECO:0000313|Ensembl:ENSP00000358961};+++[E9PLX1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf194 {ECO:0000313|Ensembl:ENSP00000435090};+++[E9PRR4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf194 {ECO:0000313|Ensembl:ENSP00000435947};"]
[127254,"'ERICH3'",1,2,0,1,{"$nulls":7},"glutamate rich 3","[ERIC3_HUMAN|Reviewed]RecName: Full=Glutamate-rich protein 3;+++[L8EC61_HUMAN|Unreviewed]SubName: Full=Alternative protein C1orf173 {ECO:0000313|EMBL:CCQ43007.1};+++[R4GMY5_HUMAN|Unreviewed]SubName: Full=Glutamate-rich protein 3 {ECO:0000313|Ensembl:ENSP00000473404};"]
[127933,"'UHMK1'",963,1003,731,899,{"$nulls":4},"GO:0071598///neuronal ribonucleoprotein granule+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0032839///dendrite cytoplasm+++GO:0030424///axon","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0004672///protein kinase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding","GO:0016310///phosphorylation+++GO:0031175///neuron projection development+++GO:0006468///protein phosphorylation+++GO:0045948///positive regulation of translational initiation+++GO:0046777///protein autophosphorylation+++GO:0046825///regulation of protein export from nucleus+++GO:0007050///cell cycle arrest+++GO:0018105///peptidyl-serine phosphorylation","U2AF homology motif kinase 1","[UHMK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Kist; EC=2.7.11.1; AltName: Full=Kinase interacting with stathmin; AltName: Full=PAM COOH-terminal interactor protein 2; Short=P-CIP2; AltName: Full=U2AF homology motif kinase 1;"]
[128077,"'LIX1L'",392.8,397.05,429.58,406.476666666667,"04391///Hippo signaling pathway - fly",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0097352///autophagosome maturation+++GO:0006914///autophagy","limb and CNS expressed 1 like","[LIX1L_HUMAN|Reviewed]RecName: Full=LIX1-like protein;+++[B3KY58_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46901 fis, clone UTERU3023141, highly similar to LIX1-like protein {ECO:0000313|EMBL:BAG54720.1};+++[L8EBF5_HUMAN|Unreviewed]SubName: Full=Alternative protein LIX1L {ECO:0000313|EMBL:CCQ43883.1};"]
[128674,"'PROKR2'",0,1,0,0.333333333333333,null,"H00255///Hypogonadotropic hypogonadism",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004983///neuropeptide Y receptor activity","GO:0007623///circadian rhythm+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway","prokineticin receptor 2","[PKR2_HUMAN|Reviewed]RecName: Full=Prokineticin receptor 2; Short=PK-R2; AltName: Full=G-protein coupled receptor 73-like 1; AltName: Full=G-protein coupled receptor I5E; AltName: Full=GPR73b; AltName: Full=GPRg2;+++[A8K1T0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76003, highly similar to Homo sapiens G protein-coupled receptor 73-like 1 (GPR73L1), mRNA {ECO:0000313|EMBL:BAF82684.1};"]
[1287,"'COL4A5'",987,952,732,890.333333333333,"05165///Human papillomavirus infection+++04151///PI3K-Akt signaling pathway+++04512///ECM-receptor interaction+++04510///Focal adhesion+++04974///Protein digestion and absorption+++05222///Small cell lung cancer+++05200///Pathways in cancer+++04926///Relaxin signaling pathway+++05146///Amoebiasis+++04933///AGE-RAGE signaling pathway in diabetic complications","H00839///Porencephaly+++H01640///Uterine leiomyoma+++H00582///Benign familial hematuria+++H00877///Brain small vessel disease with hemorrhage+++H00579///Hereditary angiopathy with nephropathy, aneurysms, and muscle cramps (HANAC)+++H00581///Alport syndrome",null,null,"GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005581///collagen trimer+++GO:0005587///collagen type IV trimer+++GO:0005604///basement membrane+++GO:0031594///neuromuscular junction+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix","GO:0005201///extracellular matrix structural constituent+++GO:0030020///extracellular matrix structural constituent conferring tensile strength","GO:0030198///extracellular matrix organization+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0007528///neuromuscular junction development","collagen type IV alpha 5 chain","[CO4A5_HUMAN|Reviewed]RecName: Full=Collagen alpha-5(IV) chain; Flags: Precursor;+++[A0A0A0U994_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha 5 transcript variant 2 {ECO:0000313|EMBL:AIW39922.1};+++[A0A2R8Y5W0_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000495101};+++[A7MBN3_HUMAN|Unreviewed]SubName: Full=Collagen, type IV, alpha 5 {ECO:0000313|EMBL:AAI51847.1};+++[H0Y998_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000423520}; Flags: Fragment;+++[H0Y9H0_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000424137}; Flags: Fragment;+++[H0Y9R8_HUMAN|Unreviewed]SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000424845}; Flags: Fragment;+++[Q49AM6_HUMAN|Unreviewed]SubName: Full=COL4A5 protein {ECO:0000313|EMBL:AAH35387.1}; SubName: Full=Collagen alpha-5(IV) chain {ECO:0000313|Ensembl:ENSP00000495685};+++[V9H0C7_HUMAN|Unreviewed]SubName: Full=COL4A5 protein {ECO:0000313|EMBL:AAC60613.1}; Flags: Fragment;"]
[1294,"'COL7A1'",526,699,615,613.333333333333,"04974///Protein digestion and absorption","H01307///Nonsyndromic congenital nail disorder (NDNC)+++H00587///Epidermolysis bullosa, dysprophica+++H00763///Transient bullous dermolysis of the newborn",null,null,"GO:0005604///basement membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0005576///extracellular region+++GO:0005581///collagen trimer+++GO:0031012///extracellular matrix+++GO:0000139///Golgi membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0005590///collagen type VII trimer+++GO:0005788///endoplasmic reticulum lumen","GO:0005515///protein binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0030414///peptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity","GO:0030198///extracellular matrix organization+++GO:0048208///COPII vesicle coating+++GO:0010951///negative regulation of endopeptidase activity+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0008544///epidermis development+++GO:0007155///cell adhesion+++GO:0010466///negative regulation of peptidase activity+++GO:0003429///growth plate cartilage chondrocyte morphogenesis+++GO:0035987///endodermal cell differentiation","collagen type VII alpha 1 chain","[CO7A1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(VII) chain; AltName: Full=Long-chain collagen; Short=LC collagen; Flags: Precursor;+++[A9Z119_HUMAN|Unreviewed]SubName: Full=Collagen type VII alpha 1 {ECO:0000313|EMBL:ABY47929.1}; Flags: Fragment;+++[B0LXL0_HUMAN|Unreviewed]SubName: Full=Type VII collagen {ECO:0000313|EMBL:ABY84701.1}; Flags: Fragment;+++[C9JBL3_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(VII) chain {ECO:0000313|Ensembl:ENSP00000391608}; Flags: Fragment;+++[Q59F16_HUMAN|Unreviewed]SubName: Full=Alpha 1 type VII collagen variant {ECO:0000313|EMBL:BAD92882.1}; Flags: Fragment;"]
[1297,"'COL9A1'",80,25,60,55,"04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++04974///Protein digestion and absorption+++04510///Focal adhesion+++04512///ECM-receptor interaction","H00476///Multiple epiphyseal dysplasia (MED)+++H02072///Stickler syndrome",null,null,"GO:0031012///extracellular matrix+++GO:0005594///collagen type IX trimer+++GO:0005788///endoplasmic reticulum lumen+++GO:0005615///extracellular space+++GO:0005581///collagen trimer+++GO:0005576///extracellular region","GO:0046872///metal ion binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0005201///extracellular matrix structural constituent","GO:0009887///animal organ morphogenesis+++GO:0030198///extracellular matrix organization","collagen type IX alpha 1 chain","[CO9A1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(IX) chain; Flags: Precursor;+++[A0A1B1SMR9_HUMAN|Unreviewed]SubName: Full=Collagen type IX alpha 1 {ECO:0000313|EMBL:ANV22053.1};+++[A0A2R8YG47_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(IX) chain {ECO:0000313|Ensembl:ENSP00000495638};"]
[1303,"'COL12A1'",4073,3197,2189,3153,"04974///Protein digestion and absorption","H01340///Bethlem myopathy+++H01778///Ullrich disease",null,null,"GO:0005595///collagen type XII trimer+++GO:0031012///extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0005581///collagen trimer+++GO:0005576///extracellular region+++GO:1903561///extracellular vesicle+++GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space","GO:0030020///extracellular matrix structural constituent conferring tensile strength","GO:0030199///collagen fibril organization+++GO:0035987///endodermal cell differentiation+++GO:0001501///skeletal system development+++GO:0003429///growth plate cartilage chondrocyte morphogenesis+++GO:0007155///cell adhesion","collagen type XII alpha 1 chain","[COCA1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(XII) chain; Flags: Precursor;+++[A0A087X0A8_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XII) chain {ECO:0000313|Ensembl:ENSP00000483232};+++[B9EJB8_HUMAN|Unreviewed]SubName: Full=Collagen, type XII, alpha 1 {ECO:0000313|EMBL:AAI46869.1};+++[D6RGG3_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XII) chain {ECO:0000313|Ensembl:ENSP00000421216};+++[H0Y4P7_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XII) chain {ECO:0000313|Ensembl:ENSP00000393217}; Flags: Fragment;+++[H0Y5N9_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XII) chain {ECO:0000313|Ensembl:ENSP00000399812}; Flags: Fragment;+++[H0Y991_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XII) chain {ECO:0000313|Ensembl:ENSP00000423423}; Flags: Fragment;"]
[130589,"'GALM'",388,476,419,427.666666666667,"00052///Galactose metabolism+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00010///Glycolysis / Gluconeogenesis",null,"M00632///Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P","R10619///D-galactose 1-epimerase; aldose   D-Galactose <=> alpha-D-Galactose+++R01602///D-glucose 1-epimerase   alpha-D-Glucose <=> beta-D-Glucose","GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0016853///isomerase activity+++GO:0030246///carbohydrate binding+++GO:0003824///catalytic activity+++GO:0004034///aldose 1-epimerase activity","GO:0019318///hexose metabolic process+++GO:0033499///galactose catabolic process via UDP-galactose+++GO:0005975///carbohydrate metabolic process+++GO:0006006///glucose metabolic process+++GO:0006012///galactose metabolic process","galactose mutarotase","[GALM_HUMAN|Reviewed]RecName: Full=Aldose 1-epimerase; EC=5.1.3.3; AltName: Full=Galactose mutarotase;+++[B8ZZ75_HUMAN|Unreviewed]SubName: Full=Aldose 1-epimerase {ECO:0000313|Ensembl:ENSP00000386233};+++[H7C1B5_HUMAN|Unreviewed]SubName: Full=Aldose 1-epimerase {ECO:0000313|Ensembl:ENSP00000399473}; Flags: Fragment;+++[H7C320_HUMAN|Unreviewed]SubName: Full=Aldose 1-epimerase {ECO:0000313|Ensembl:ENSP00000409083}; Flags: Fragment;"]
[131076,"'CCDC58'",55,74,55,61.3333333333333,null,"H00737///Peeling skin syndrome+++H01995///Unverricht-Lundborg disease+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,null,"GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005198///structural molecule activity+++GO:0002020///protease binding+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0030674///protein binding, bridging","GO:0098609///cell-cell adhesion+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation+++GO:0070268///cornification+++GO:0010466///negative regulation of peptidase activity+++GO:0045861///negative regulation of proteolysis","coiled-coil domain containing 58","[CCD58_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 58;+++[C9JBU9_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 58 {ECO:0000313|Ensembl:ENSP00000420769};+++[C9JQ41_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 58 {ECO:0000313|Ensembl:ENSP00000420248};+++[H7C525_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 58 {ECO:0000313|Ensembl:ENSP00000418810}; Flags: Fragment;"]
[131578,"'LRRC15'",1701,1712,1551,1654.66666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0016020///membrane","GO:0005518///collagen binding+++GO:0001968///fibronectin binding+++GO:0043236///laminin binding","GO:0030335///positive regulation of cell migration+++GO:1903077///negative regulation of protein localization to plasma membrane","leucine rich repeat containing 15","[LRC15_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 15; AltName: Full=Leucine-rich repeat protein induced by beta-amyloid homolog; Short=hLib; Flags: Precursor;+++[B3KWI4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43122 fis, clone CTONG3003737, highly similar to Leucine-rich repeat-containing protein 15 {ECO:0000313|EMBL:BAG54146.1};"]
[132112,"'RTP1'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0031849///olfactory receptor binding","GO:0051205///protein insertion into membrane+++GO:0006612///protein targeting to membrane+++GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste","receptor transporter protein 1","[RTP1_HUMAN|Reviewed]RecName: Full=Receptor-transporting protein 1; AltName: Full=3CxxC-type zinc finger protein 1;"]
[132789,"'GNPDA2'",179,154,164,165.666666666667,"01100///Metabolic pathways+++00520///Amino sugar and nucleotide sugar metabolism","H00606///Early infantile epileptic encephalopathy",null,"R00765///D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); D-glucosamine-6-phosphate   D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia","GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0016787///hydrolase activity+++GO:0004342///glucosamine-6-phosphate deaminase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0005975///carbohydrate metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006046///N-acetylglucosamine catabolic process+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0006043///glucosamine catabolic process","glucosamine-6-phosphate deaminase 2","[GNPI2_HUMAN|Reviewed]RecName: Full=Glucosamine-6-phosphate isomerase 2; EC=3.5.99.6; AltName: Full=Glucosamine-6-phosphate deaminase 2; Short=GNPDA 2; Short=GlcN6P deaminase 2; AltName: Full=Glucosamine-6-phosphate isomerase SB52;+++[A0A024R9X5_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197};+++[V9GYK3_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 2 {ECO:0000313|Ensembl:ENSP00000476853}; Flags: Fragment;+++[V9GYW0_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 2 {ECO:0000313|Ensembl:ENSP00000477137}; Flags: Fragment;"]
[133482,"'SLCO6A1'",0,0,1,0.333333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0005215///transporter activity+++GO:0015347///sodium-independent organic anion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0043252///sodium-independent organic anion transport","solute carrier organic anion transporter family member 6A1","[SO6A1_HUMAN|Reviewed]RecName: Full=Solute carrier organic anion transporter family member 6A1; AltName: Full=Cancer/testis antigen 48; Short=CT48; AltName: Full=Gonad-specific transporter; Short=GST; AltName: Full=Organic anion-transporting polypeptide 6A1; AltName: Full=Organic anion-transporting polypeptide I; Short=OATP-I; AltName: Full=Solute carrier family 21 member 19;+++[A0A140VJU7_HUMAN|Unreviewed]RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};+++[C9J020_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family member 6A1 {ECO:0000313|Ensembl:ENSP00000421990};+++[D3DSZ4_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family, member 6A1, isoform CRA_b {ECO:0000313|EMBL:EAW49097.1};+++[H0Y8R6_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family member 6A1 {ECO:0000313|Ensembl:ENSP00000421846}; Flags: Fragment;"]
[134218,"'DNAJC21'",518.08,457.66,488.83,488.19,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005840///ribosome+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0006457///protein folding","DnaJ heat shock protein family (Hsp40) member C21","[DJC21_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily C member 21; AltName: Full=DnaJ homolog subfamily A member 5; AltName: Full=Protein GS3;+++[A0A2R8Y4N5_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 21 {ECO:0000313|Ensembl:ENSP00000493850}; Flags: Fragment;+++[A0A2R8Y4Q0_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 21 {ECO:0000313|Ensembl:ENSP00000493883};+++[A0A2R8Y534_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 21 {ECO:0000313|Ensembl:ENSP00000494173};+++[A0A2R8YET8_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 21 {ECO:0000313|Ensembl:ENSP00000495883};"]
[134553,"'C5orf24'",1307,1291,971,1189.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"chromosome 5 open reading frame 24","[CE024_HUMAN|Reviewed]RecName: Full=UPF0461 protein C5orf24;+++[A0A1Y8EJU8_HUMAN|Unreviewed]SubName: Full=UPF0461 protein C5orf24 {ECO:0000313|Ensembl:ENSP00000422620}; Flags: Fragment;+++[H0YAE0_HUMAN|Unreviewed]SubName: Full=UPF0461 protein C5orf24 {ECO:0000313|Ensembl:ENSP00000426824}; Flags: Fragment;"]
[135293,"'PM20D2'",217.8,169,111,165.933333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0071713///para-aminobenzoyl-glutamate hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016805///dipeptidase activity","GO:0006508///proteolysis+++GO:0046657///folic acid catabolic process+++GO:0032268///regulation of cellular protein metabolic process","peptidase M20 domain containing 2","[P20D2_HUMAN|Reviewed]RecName: Full=Peptidase M20 domain-containing protein 2; AltName: Full=Aminoacylase-1-like protein 2;"]
[1360,"'CPB1'",0,0,1,0.333333333333333,"04972///Pancreatic secretion+++04974///Protein digestion and absorption",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008270///zinc ion binding+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0004181///metallocarboxypeptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006508///proteolysis","carboxypeptidase B1","[CBPB1_HUMAN|Reviewed]RecName: Full=Carboxypeptidase B; EC=3.4.17.2 {ECO:0000250|UniProtKB:P00732}; AltName: Full=Pancreas-specific protein; Short=PASP; Flags: Precursor;+++[C9J5C4_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase B {ECO:0000313|Ensembl:ENSP00000417117}; Flags: Fragment;+++[C9JUX7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase B {ECO:0000313|Ensembl:ENSP00000419427}; Flags: Fragment;+++[C9JXS3_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase B {ECO:0000313|Ensembl:ENSP00000419114}; Flags: Fragment;"]
[1370,"'CPN2'",17,15,17,16.3333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0072562///blood microparticle","GO:0004181///metallocarboxypeptidase activity+++GO:0030234///enzyme regulator activity","GO:0050821///protein stabilization+++GO:0030449///regulation of complement activation","carboxypeptidase N subunit 2","[CPN2_HUMAN|Reviewed]RecName: Full=Carboxypeptidase N subunit 2; AltName: Full=Carboxypeptidase N 83 kDa chain; AltName: Full=Carboxypeptidase N large subunit; AltName: Full=Carboxypeptidase N polypeptide 2; AltName: Full=Carboxypeptidase N regulatory subunit; Flags: Precursor;"]
[137695,"'TMEM68'",118,116,123,119,"03013///RNA transport+++04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016746///transferase activity, transferring acyl groups","GO:0008152///metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000387///spliceosomal snRNP assembly+++GO:0019216///regulation of lipid metabolic process+++GO:0009452///7-methylguanosine RNA capping+++GO:0022613///ribonucleoprotein complex biogenesis+++GO:0006351///transcription, DNA-templated+++GO:0036261///7-methylguanosine cap hypermethylation","transmembrane protein 68","[TMM68_HUMAN|Reviewed]RecName: Full=Transmembrane protein 68;+++[A0A024R7Y2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68, isoform CRA_a {ECO:0000313|EMBL:EAW86759.1};+++[E5RGT2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000428688};+++[E5RHI6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429758}; Flags: Fragment;+++[E5RHU1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429667}; Flags: Fragment;+++[E5RHZ2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000430838}; Flags: Fragment;+++[E5RJ96_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429175}; Flags: Fragment;+++[E5RJI9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000430542}; Flags: Fragment;+++[E5RJN2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000429026};+++[H0YAX4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000428236}; Flags: Fragment;+++[H0YAY9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000428318}; Flags: Fragment;+++[H0YC64_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000431018}; Flags: Fragment;+++[Q49A68_HUMAN|Unreviewed]SubName: Full=TMEM68 protein {ECO:0000313|EMBL:AAH43417.1}; SubName: Full=Transmembrane protein 68 {ECO:0000313|Ensembl:ENSP00000481143};"]
[137902,"'PXDNL'",4,10,3,5.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01159///Anterior segment dysgenesis (ASGD)",null,null,"GO:0000786///nucleosome+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005576///extracellular region","GO:0016491///oxidoreductase activity+++GO:0004518///nuclease activity+++GO:0003677///DNA binding+++GO:0004601///peroxidase activity+++GO:0016787///hydrolase activity+++GO:0020037///heme binding+++GO:0046872///metal ion binding+++GO:0004519///endonuclease activity","GO:0007275///multicellular organism development+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification+++GO:0030154///cell differentiation+++GO:0006979///response to oxidative stress+++GO:0055114///oxidation-reduction process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006323///DNA packaging+++GO:0007283///spermatogenesis+++GO:0030261///chromosome condensation","peroxidasin like","[PXDNL_HUMAN|Reviewed]RecName: Full=Peroxidasin-like protein; EC=1.11.1.7; AltName: Full=Cardiac peroxidase; AltName: Full=Vascular peroxidase 2; AltName: Full=polysomal ribonuclease 1; Short=PRM1; Flags: Precursor;+++[H0YAV0_HUMAN|Unreviewed]SubName: Full=Peroxidasin-like protein {ECO:0000313|Ensembl:ENSP00000428114}; Flags: Fragment;+++[K4DIA6_HUMAN|Unreviewed]SubName: Full=Peroxidasin-like protein {ECO:0000313|Ensembl:ENSP00000429855}; Flags: Fragment;"]
[1388,"'ATF6B'",3552,4452,4542,4182,"05030///Cocaine addiction+++04911///Insulin secretion+++04668///TNF signaling pathway+++04915///Estrogen signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++05203///Viral carcinogenesis+++04926///Relaxin signaling pathway+++05163///Human cytomegalovirus infection+++04918///Thyroid hormone synthesis+++04925///Aldosterone synthesis and secretion+++04141///Protein processing in endoplasmic reticulum+++04927///Cortisol synthesis and secretion+++04728///Dopaminergic synapse+++04934///Cushing's syndrome+++04151///PI3K-Akt signaling pathway+++05034///Alcoholism+++04211///Longevity regulating pathway+++05031///Amphetamine addiction+++04928///Parathyroid hormone synthesis, secretion and action+++05161///Hepatitis B+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0016021///integral component of membrane+++GO:0005730///nucleolus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0032993///protein-DNA complex+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0035497///cAMP response element binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding","GO:0036500///ATF6-mediated unfolded protein response+++GO:0007165///signal transduction+++GO:0006351///transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006986///response to unfolded protein+++GO:1903892///negative regulation of ATF6-mediated unfolded protein response+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","activating transcription factor 6 beta","[ATF6B_HUMAN|Reviewed]RecName: Full=Cyclic AMP-dependent transcription factor ATF-6 beta; Short=cAMP-dependent transcription factor ATF-6 beta; AltName: Full=Activating transcription factor 6 beta; Short=ATF6-beta; AltName: Full=Protein G13; AltName: Full=cAMP response element-binding protein-related protein; Short=Creb-rp; AltName: Full=cAMP-responsive element-binding protein-like 1; Contains: RecName: Full=Processed cyclic AMP-dependent transcription factor ATF-6 beta;+++[A0A1U9X796_HUMAN|Unreviewed]SubName: Full=ATF6B {ECO:0000313|EMBL:AQY76664.1};+++[H0Y7D7_HUMAN|Unreviewed]SubName: Full=Cyclic AMP-dependent transcription factor ATF-6 beta {ECO:0000313|Ensembl:ENSP00000393419}; Flags: Fragment;+++[Q6AZW6_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 6 beta {ECO:0000313|EMBL:AAH77075.1};+++[Q96QL7_HUMAN|Unreviewed]SubName: Full=ATF6B protein {ECO:0000313|EMBL:AAH08394.1}; SubName: Full=cAMP responsive element binding protein-like 1 {ECO:0000313|EMBL:AAP35691.1};"]
[139170,"'DCAF12L1'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","DDB1 and CUL4 associated factor 12 like 1","[DC121_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 12-like protein 1; AltName: Full=WD repeat-containing protein 40B;"]
[1400,"'CRMP1'",937,1210,1207,1118,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0030496///midbody+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0031005///filamin binding","GO:1904530///negative regulation of actin filament binding+++GO:0007399///nervous system development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0007411///axon guidance+++GO:0048666///neuron development+++GO:0000226///microtubule cytoskeleton organization+++GO:0010977///negative regulation of neuron projection development","collapsin response mediator protein 1","[DPYL1_HUMAN|Reviewed]RecName: Full=Dihydropyrimidinase-related protein 1; Short=DRP-1; AltName: Full=Collapsin response mediator protein 1; Short=CRMP-1; AltName: Full=Unc-33-like phosphoprotein 3; Short=ULIP-3;+++[B3KT07_HUMAN|Unreviewed]SubName: Full=Collapsin response mediator protein 1, isoform CRA_d {ECO:0000313|EMBL:EAW82406.1}; SubName: Full=cDNA FLJ37406 fis, clone BRAMY2028282, highly similar to Dihydropyrimidinase-related protein 1 {ECO:0000313|EMBL:BAG52919.1};+++[B3KV96_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16285 fis, clone OCBBF2004038, highly similar to Dihydropyrimidinase-related protein 1 {ECO:0000313|EMBL:BAG53708.1};+++[E9PD68_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-related protein 1 {ECO:0000313|Ensembl:ENSP00000425742};+++[Q96I11_HUMAN|Unreviewed]SubName: Full=CRMP1 protein {ECO:0000313|EMBL:AAH07898.2}; Flags: Fragment;+++[X5DNI1_HUMAN|Unreviewed]SubName: Full=Collapsin response mediator protein 1 isoform A {ECO:0000313|EMBL:AHW56456.1}; Flags: Fragment;+++[X5DQV1_HUMAN|Unreviewed]SubName: Full=Collapsin response mediator protein 1 isoform B {ECO:0000313|EMBL:AHW56457.1}; Flags: Fragment;"]
[140462,"'ASB9'",3,0,9,4,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0043687///post-translational protein modification+++GO:0045732///positive regulation of protein catabolic process+++GO:0035556///intracellular signal transduction","ankyrin repeat and SOCS box containing 9","[ASB9_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 9; Short=ASB-9;+++[A0A024RBW2_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box-containing 9, isoform CRA_b {ECO:0000313|EMBL:EAW98873.1};+++[A0A024RBW7_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box-containing 9, isoform CRA_a {ECO:0000313|EMBL:EAW98876.1}; SubName: Full=Testis tissue sperm-binding protein Li 57p {ECO:0000313|EMBL:AEE60937.1};+++[A0A024RBZ4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box-containing 9, isoform CRA_d {ECO:0000313|EMBL:EAW98875.1};+++[Q7Z4A2_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box-containing 9 {ECO:0000313|EMBL:AAQ17469.1};+++[R4GN94_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 9 {ECO:0000313|Ensembl:ENSP00000473542}; Flags: Fragment;"]
[140688,"'NOL4L'",1094,1083,934,1037,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01481///Myelodysplastic syndrome (MDS)+++H02047///Bohring-Opitz syndrome",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0032526///response to retinoic acid+++GO:0060430///lung saccule development+++GO:0003007///heart morphogenesis+++GO:0045599///negative regulation of fat cell differentiation+++GO:0048872///homeostasis of number of cells+++GO:0016579///protein deubiquitination+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:0048538///thymus development+++GO:0030097///hemopoiesis+++GO:0048539///bone marrow development+++GO:0035359///negative regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway","nucleolar protein 4 like","[NOL4L_HUMAN|Reviewed]RecName: Full=Nucleolar protein 4-like;+++[A0A087WTU5_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000478146};+++[A0A087X0N3_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000483523};+++[A0A1W2PQU1_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000492149};+++[H0Y778_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000410774}; Flags: Fragment;+++[Q5JYB6_HUMAN|Unreviewed]SubName: Full=Chromosome 20 open reading frame 112, isoform CRA_d {ECO:0000313|EMBL:EAW76370.1}; SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000317413};+++[Q5JYC0_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000364830};+++[Q5JYC2_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000364829}; Flags: Fragment;+++[Q5W149_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000201961}; Flags: Fragment;+++[Q6P0R2_HUMAN|Unreviewed]SubName: Full=LOC284804 protein {ECO:0000313|EMBL:AAH65483.1}; Flags: Fragment;"]
[140825,"'NEURL2'",33.42,19.51,29.33,27.42,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol",null,"GO:0043687///post-translational protein modification+++GO:0035556///intracellular signal transduction+++GO:0016567///protein ubiquitination","neuralized E3 ubiquitin protein ligase 2","[NEUL2_HUMAN|Reviewed]RecName: Full=Neuralized-like protein 2;+++[H0YGA6_HUMAN|Unreviewed]SubName: Full=Neuralized-like protein 2 {ECO:0000313|Ensembl:ENSP00000442383}; Flags: Fragment;"]
[140894,"'CNBD2'",0,4,3.09,2.36333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0030552///cAMP binding","GO:0007283///spermatogenesis","cyclic nucleotide binding domain containing 2","[CNBD2_HUMAN|Reviewed]RecName: Full=Cyclic nucleotide-binding domain-containing protein 2;+++[A0A087WUQ5_HUMAN|Unreviewed]SubName: Full=Cyclic nucleotide-binding domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000478833}; Flags: Fragment;+++[A0A087WVB8_HUMAN|Unreviewed]SubName: Full=Cyclic nucleotide-binding domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000479333}; Flags: Fragment;+++[Q4G141_HUMAN|Unreviewed]SubName: Full=C20orf152 protein {ECO:0000313|EMBL:AAH30782.1}; SubName: Full=Cyclic nucleotide-binding domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000480804};+++[U3KQM1_HUMAN|Unreviewed]SubName: Full=Cyclic nucleotide-binding domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000476014};"]
[1431,"'CS'",2515,2174,2312,2333.66666666667,"00630///Glyoxylate and dicarboxylate metabolism+++01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++01210///2-Oxocarboxylic acid metabolism+++01200///Carbon metabolism+++01230///Biosynthesis of amino acids+++01110///Biosynthesis of secondary metabolites+++00020///Citrate cycle (TCA cycle)+++01130///Biosynthesis of antibiotics",null,"M00012///Glyoxylate cycle+++M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00740///Methylaspartate cycle+++M00010///Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate","R00351///acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)   Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate","GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0004108///citrate (Si)-synthase activity+++GO:0046912///transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer+++GO:0016740///transferase activity+++GO:0003723///RNA binding","GO:0005975///carbohydrate metabolic process+++GO:0006101///citrate metabolic process+++GO:0006099///tricarboxylic acid cycle","citrate synthase","[CISY_HUMAN|Reviewed]RecName: Full=Citrate synthase, mitochondrial; EC=2.3.3.1; AltName: Full=Citrate (Si)-synthase; Flags: Precursor;+++[A0A024RB75_HUMAN|Unreviewed]RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};+++[A0A0C4DGI3_HUMAN|Unreviewed]RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};+++[B4DJV2_HUMAN|Unreviewed]RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};+++[F8VPA1_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450312}; Flags: Fragment;+++[F8VPF9_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450101}; Flags: Fragment;+++[F8VR34_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000450403}; Flags: Fragment;+++[F8VRI6_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000448667}; Flags: Fragment;+++[F8VRP1_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000448409}; Flags: Fragment;+++[F8VTT8_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447986}; Flags: Fragment;+++[F8VU34_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447948}; Flags: Fragment;+++[F8VVY4_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000449571};+++[F8VWQ5_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000449491};+++[F8VX07_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000449753}; Flags: Fragment;+++[F8VX68_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000449427}; Flags: Fragment;+++[F8VZK9_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447346}; Flags: Fragment;+++[F8W0J2_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447582};+++[F8W1S4_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447442}; Flags: Fragment;+++[F8W4S1_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000448172}; Flags: Fragment;+++[F8W642_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000448166}; Flags: Fragment;+++[H0YH82_HUMAN|Unreviewed]SubName: Full=Citrate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000446492}; Flags: Fragment;+++[H0YIC4_HUMAN|Unreviewed]RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441}; Flags: Fragment;+++[Q0QEL2_HUMAN|Unreviewed]RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441}; Flags: Fragment;"]
[143458,"'LDLRAD3'",138,190,129,152.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0001540///amyloid-beta binding","GO:0006898///receptor-mediated endocytosis+++GO:0070613///regulation of protein processing","low density lipoprotein receptor class A domain containing 3","[LRAD3_HUMAN|Reviewed]RecName: Full=Low-density lipoprotein receptor class A domain-containing protein 3; Short=LDLR class A domain-containing protein 3; Flags: Precursor;+++[E9PR86_HUMAN|Unreviewed]SubName: Full=Low-density lipoprotein receptor class A domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000434313};"]
[144110,"'TMEM86A'",626,518,441,528.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0047409///alkenylglycerophosphoethanolamine hydrolase activity+++GO:0047408///alkenylglycerophosphocholine hydrolase activity","GO:0046485///ether lipid metabolic process","transmembrane protein 86A","[TM86A_HUMAN|Reviewed]RecName: Full=Lysoplasmalogenase-like protein TMEM86A; AltName: Full=Transmembrane protein 86A;"]
[144404,"'TMEM120B'",479,441,536,485.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0051291///protein heterooligomerization+++GO:0045444///fat cell differentiation+++GO:0008150///biological_process","transmembrane protein 120B","[T120B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 120B;+++[F5H465_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 120B {ECO:0000313|Ensembl:ENSP00000446159};+++[H0YG77_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 120B {ECO:0000313|Ensembl:ENSP00000442105}; Flags: Fragment;"]
[144811,"'LACC1'",24,24,33,27,"00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++00561///Glycerolipid metabolism+++01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway+++05231///Choline metabolism in cancer","H01657///Nephrotic syndrome+++H01726///Membranoproliferative glomerulonephritis",null,"R02240///ATP:1,2-diacylglycerol 3-phosphotransferase ATP + 1,2-Diacyl-sn-glycerol <=> ADP + Phosphatidate","GO:0005777///peroxisome","GO:0005507///copper ion binding+++GO:0005515///protein binding","GO:0016477///cell migration+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0046834///lipid phosphorylation+++GO:0030168///platelet activation+++GO:0046486///glycerolipid metabolic process+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0046339///diacylglycerol metabolic process+++GO:0035556///intracellular signal transduction","laccase domain containing 1","[LACC1_HUMAN|Reviewed]RecName: Full=Laccase domain-containing protein 1; AltName: Full=Fatty acid metabolism-immunity nexus {ECO:0000303|PubMed:27478939};+++[A2A3Z5_HUMAN|Unreviewed]SubName: Full=Laccase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000394179}; Flags: Fragment;"]
[145483,"'FAM161B'",206,219,159,194.666666666667,{"$nulls":4},"GO:0015630///microtubule cytoskeleton+++GO:0005881///cytoplasmic microtubule","GO:0005515///protein binding","GO:0044782///cilium organization+++GO:0008150///biological_process","FAM161B, centrosomal protein","[F161B_HUMAN|Reviewed]RecName: Full=Protein FAM161B;+++[A0A024R6F8_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 44, isoform CRA_a {ECO:0000313|EMBL:EAW81145.1};+++[H0YJ62_HUMAN|Unreviewed]SubName: Full=Protein FAM161B {ECO:0000313|Ensembl:ENSP00000450889}; Flags: Fragment;"]
[145508,"'CEP128'",15,29,18,20.6666666666667,"04923///Regulation of lipolysis in adipocytes+++05320///Autoimmune thyroid disease+++04918///Thyroid hormone synthesis+++04080///Neuroactive ligand-receptor interaction+++04024///cAMP signaling pathway","H00250///Congenital nongoitrous hypothyroidism (CHNG)+++H01269///Congenital hyperthyroidism",null,null,"GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005814///centriole+++GO:0000922///spindle pole+++GO:0120103///centriolar subdistal appendage+++GO:0005737///cytoplasm","GO:0004996///thyroid-stimulating hormone receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0044877///protein-containing complex binding+++GO:0038023///signaling receptor activity","GO:0008104///protein localization","centrosomal protein 128","[CE128_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 128 kDa; Short=Cep128;+++[G3V3F4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000451214}; Flags: Fragment;+++[G3V3U2_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000451428}; Flags: Fragment;+++[G3V4J9_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000451849}; Flags: Fragment;+++[G9BAV9_HUMAN|Unreviewed]SubName: Full=Lens epithelium-derived protein {ECO:0000313|EMBL:ADP09384.1};+++[H0YIZ9_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000450555}; Flags: Fragment;+++[H0YJD7_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000451273}; Flags: Fragment;+++[H0YJE3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000451319}; Flags: Fragment;+++[H0YJH2_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000451501}; Flags: Fragment;+++[Q86TS1_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 128 kDa {ECO:0000313|Ensembl:ENSP00000451137}; SubName: Full=Full-length cDNA 5-PRIME end of clone CS0CAP003YE19 of Thymus of Homo sapiens (human) {ECO:0000313|EMBL:CAD66553.1}; Flags: Fragment;+++[Q8N3Z7_HUMAN|Unreviewed]SubName: Full=C14orf145 protein {ECO:0000313|EMBL:AAH36939.1}; Flags: Fragment;"]
[146279,"'TEKT5'",2,5,2,3,{"$nulls":4},"GO:0005929///cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0031514///motile cilium+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0060294///cilium movement involved in cell motility+++GO:0060271///cilium assembly+++GO:0030317///flagellated sperm motility","tektin 5","[TEKT5_HUMAN|Reviewed]RecName: Full=Tektin-5;+++[I3L1F7_HUMAN|Unreviewed]SubName: Full=Tektin-5 {ECO:0000313|Ensembl:ENSP00000458802}; Flags: Fragment;"]
[146325,"'PRR35'",1,0,0,0.333333333333333,{"$nulls":7},"proline rich 35","[PRR35_HUMAN|Reviewed]RecName: Full=Proline-rich protein 35; AltName: Full=Uncharacterized protein RJD1;"]
[146691,"'TOM1L2'",2616,2521,2682,2606.33333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005623///cell","GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0007165///signal transduction","target of myb1 like 2 membrane trafficking protein","[TM1L2_HUMAN|Reviewed]RecName: Full=TOM1-like protein 2; AltName: Full=Target of Myb-like protein 2;+++[B7Z2U2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 2 {ECO:0000313|Ensembl:ENSP00000437655}; SubName: Full=cDNA FLJ54050, highly similar to Homo sapiens target of myb1-like 2 (TOM1L2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAH11978.1};+++[B7Z671_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54058, highly similar to Homo sapiens target of myb1-like 2 (TOM1L2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAH13157.1};+++[F5H3S6_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 2 {ECO:0000313|Ensembl:ENSP00000445188};+++[K7EKL6_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 2 {ECO:0000313|Ensembl:ENSP00000465677}; Flags: Fragment;+++[K7ENB0_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 2 {ECO:0000313|Ensembl:ENSP00000466863}; Flags: Fragment;"]
[146956,"'EME1'",30,13,23,22,"03440///Homologous recombination+++03460///Fanconi anemia pathway",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0048476///Holliday junction resolvase complex+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005720///nuclear heterochromatin","GO:0005515///protein binding+++GO:0004518///nuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0008821///crossover junction endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0003677///DNA binding","GO:0031573///intra-S DNA damage checkpoint+++GO:0006302///double-strand break repair+++GO:0072429///response to intra-S DNA damage checkpoint signaling+++GO:0006310///DNA recombination+++GO:0000712///resolution of meiotic recombination intermediates+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031297///replication fork processing+++GO:0006281///DNA repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0036297///interstrand cross-link repair","essential meiotic structure-specific endonuclease 1","[EME1_HUMAN|Reviewed]RecName: Full=Crossover junction endonuclease EME1; EC=3.1.22.-; AltName: Full=MMS4 homolog; Short=hMMS4;+++[D6RIT8_HUMAN|Unreviewed]SubName: Full=Crossover junction endonuclease EME1 {ECO:0000313|Ensembl:ENSP00000427392};+++[F8W714_HUMAN|Unreviewed]SubName: Full=Crossover junction endonuclease EME1 {ECO:0000313|Ensembl:ENSP00000423029}; Flags: Fragment;+++[H0Y9Z4_HUMAN|Unreviewed]SubName: Full=Crossover junction endonuclease EME1 {ECO:0000313|Ensembl:ENSP00000425567}; Flags: Fragment;"]
[147407,"'SLC25A52'",0,3.03,4,2.34333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport","solute carrier family 25 member 52","[S2552_HUMAN|Reviewed]RecName: Full=Solute carrier family 25 member 52; AltName: Full=Mitochondrial carrier triple repeat protein 2;+++[I3L0B8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 52 {ECO:0000313|Ensembl:ENSP00000372612};"]
[147699,"'PPM1N'",12,13,22,15.6666666666667,{"$nulls":5},"GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0003824///catalytic activity","GO:0006470///protein dephosphorylation","protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)","[PPM1N_HUMAN|Reviewed]RecName: Full=Probable protein phosphatase 1N; EC=3.1.3.16;+++[A8MXX7_HUMAN|Unreviewed]SubName: Full=Probable protein phosphatase 1N {ECO:0000313|Ensembl:ENSP00000379962};+++[B5MCQ2_HUMAN|Unreviewed]SubName: Full=Probable protein phosphatase 1N {ECO:0000313|Ensembl:ENSP00000384809};+++[E7ENL9_HUMAN|Unreviewed]SubName: Full=Probable protein phosphatase 1N {ECO:0000313|Ensembl:ENSP00000389871};+++[H7C347_HUMAN|Unreviewed]SubName: Full=Probable protein phosphatase 1N {ECO:0000313|Ensembl:ENSP00000409511}; Flags: Fragment;"]
[147923,"'ZNF420'",45,47,36,42.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042981///regulation of apoptotic process","zinc finger protein 420","[ZN420_HUMAN|Reviewed]RecName: Full=Zinc finger protein 420;+++[K7EJW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 420 {ECO:0000313|Ensembl:ENSP00000465346};+++[K7ELF6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 420 {ECO:0000313|Ensembl:ENSP00000466057}; Flags: Fragment;+++[K7EPG0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 420 {ECO:0000313|Ensembl:ENSP00000467369};+++[K7EQC9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 420 {ECO:0000313|Ensembl:ENSP00000467772}; Flags: Fragment;+++[K7ERS3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 420 {ECO:0000313|Ensembl:ENSP00000468387}; Flags: Fragment;+++[K7ESJ1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 420 {ECO:0000313|Ensembl:ENSP00000468736}; Flags: Fragment;"]
[148170,"'CDC42EP5'",15,30,27,24,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system+++GO:0005737///cytoplasm","GO:0017049///GTP-Rho binding","GO:0031274///positive regulation of pseudopodium assembly+++GO:0007266///Rho protein signal transduction+++GO:0007254///JNK cascade+++GO:0030838///positive regulation of actin filament polymerization+++GO:0008360///regulation of cell shape","CDC42 effector protein 5","[BORG3_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 5; AltName: Full=Binder of Rho GTPases 3;+++[A0A0G2JPE9_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 5 {ECO:0000313|Ensembl:ENSP00000483465}; Flags: Fragment;"]
[148479,"'PHF13'",235,245,187,222.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0035064///methylated histone binding","GO:0007059///chromosome segregation+++GO:0007076///mitotic chromosome condensation+++GO:0006325///chromatin organization+++GO:0030261///chromosome condensation+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0051301///cell division","PHD finger protein 13","[PHF13_HUMAN|Reviewed]RecName: Full=PHD finger protein 13; AltName: Full=Survival time-associated PHD finger protein in ovarian cancer 1; Short=SPOC1;+++[A0A158RFV6_HUMAN|Unreviewed]SubName: Full=PHD finger protein SPOC1 {ECO:0000313|EMBL:AAL58478.1};"]
[148979,"'GLIS1'",26,13,15,18,null,"H00512///Permanent neonatal diabetes mellitus (PNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","GLIS family zinc finger 1","[GLIS1_HUMAN|Reviewed]RecName: Full=Zinc finger protein GLIS1; AltName: Full=GLI-similar 1;+++[A0A0D9SEX9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein GLIS1 {ECO:0000313|Ensembl:ENSP00000486112};"]
[149478,"'BTBD19'",351,450,313,371.333333333333,{"$nulls":7},"BTB domain containing 19","[BTBDJ_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein 19;+++[A0A0A0MSF5_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing protein 19 {ECO:0000313|Ensembl:ENSP00000386506};"]
[149986,"'LSM14B'",548,586,525,553,"03050///Proteasome",null,"M00337///Immunoproteasome+++M00340///Proteasome, 20S core particle",null,"GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0098794///postsynapse+++GO:0000502///proteasome complex+++GO:0005829///cytosol+++GO:0005839///proteasome core complex","GO:0003723///RNA binding","GO:0007275///multicellular organism development+++GO:0006417///regulation of translation","LSM family member 14B","[LS14B_HUMAN|Reviewed]RecName: Full=Protein LSM14 homolog B; AltName: Full=Protein FAM61B; AltName: Full=RNA-associated protein 55B; Short=hRAP55B;+++[A0A0C4DFV2_HUMAN|Unreviewed]SubName: Full=Protein LSM14 homolog B {ECO:0000313|Ensembl:ENSP00000359953};+++[Q5TBP9_HUMAN|Unreviewed]SubName: Full=Protein LSM14 homolog B {ECO:0000313|Ensembl:ENSP00000355209}; Flags: Fragment;+++[Q5TBQ0_HUMAN|Unreviewed]SubName: Full=Protein LSM14 homolog B {ECO:0000313|Ensembl:ENSP00000383172}; Flags: Fragment;+++[Q5TBQ1_HUMAN|Unreviewed]SubName: Full=Protein LSM14 homolog B {ECO:0000313|Ensembl:ENSP00000279069}; Flags: Fragment;"]
[150372,"'NFAM1'",2,1,8.03,3.67666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0035577///azurophil granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004888///transmembrane signaling receptor activity","GO:0001819///positive regulation of cytokine production+++GO:0035556///intracellular signal transduction+++GO:0045577///regulation of B cell differentiation+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0007166///cell surface receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0007165///signal transduction+++GO:0043312///neutrophil degranulation","NFAT activating protein with ITAM motif 1","[NFAM1_HUMAN|Reviewed]RecName: Full=NFAT activation molecule 1; AltName: Full=Calcineurin/NFAT-activating ITAM-containing protein; AltName: Full=NFAT-activating protein with ITAM motif 1; Flags: Precursor;+++[F8WE95_HUMAN|Unreviewed]SubName: Full=NFAT activation molecule 1 {ECO:0000313|Ensembl:ENSP00000347650};"]
[150737,"'TTC30B'",84.8,49.17,43.22,59.0633333333333,{"$nulls":4},"GO:0042995///cell projection+++GO:0030992///intraciliary transport particle B+++GO:0097542///ciliary tip+++GO:0005929///cilium","GO:0005515///protein binding","GO:0035735///intraciliary transport involved in cilium assembly+++GO:0030030///cell projection organization+++GO:0042073///intraciliary transport","tetratricopeptide repeat domain 30B","[TT30B_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 30B; Short=TPR repeat protein 30B;"]
[151011,"'SEPT10'",395,411,315,373.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005940///septin ring+++GO:0032160///septin filament array+++GO:0031105///septin complex+++GO:0005737///cytoplasm","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity","GO:0007049///cell cycle+++GO:0060271///cilium assembly+++GO:0000281///mitotic cytokinesis+++GO:0000921///septin ring assembly+++GO:0051301///cell division","septin 10","[SEP10_HUMAN|Reviewed]RecName: Full=Septin-10;+++[B5ME97_HUMAN|Unreviewed]SubName: Full=Septin 10, isoform CRA_c {ECO:0000313|EMBL:EAW53860.1}; SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000349116};+++[B7Z277_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59501, highly similar to Septin-10 {ECO:0000313|EMBL:BAH11763.1};+++[B7Z371_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55844, highly similar to Septin-10 {ECO:0000313|EMBL:BAH12107.1};+++[C9JEQ7_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000416597}; Flags: Fragment;+++[C9JEW2_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000396051}; Flags: Fragment;+++[C9JNR7_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000408392}; Flags: Fragment;+++[E7EW69_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000396728};+++[E7EX04_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000407790};+++[F5GYV2_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000441218}; Flags: Fragment;+++[F5H1F2_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000445707}; Flags: Fragment;+++[F5H1W3_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000446331};+++[F8WC85_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000399270};+++[Q59H84_HUMAN|Unreviewed]SubName: Full=Septin 10 isoform 2 variant {ECO:0000313|EMBL:BAD92112.1}; Flags: Fragment;+++[Q9H9P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12620 fis, clone NT2RM4001714, moderately similar to SEPTIN 2 HOMOLOG {ECO:0000313|EMBL:BAB14176.1};"]
[1515,"'CTSV'",19600,19461,20671,19910.6666666667,"04210///Apoptosis+++04142///Lysosome",{"$nulls":3},"GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0043204///perikaryon+++GO:0005764///lysosome+++GO:0043202///lysosomal lumen+++GO:0005902///microvillus+++GO:0005773///vacuole+++GO:0009897///external side of plasma membrane+++GO:0005576///extracellular region+++GO:0045177///apical part of cell+++GO:0005615///extracellular space+++GO:0030141///secretory granule","GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0004177///aminopeptidase activity+++GO:0044877///protein-containing complex binding+++GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0030984///kininogen binding+++GO:0005515///protein binding","GO:1990834///response to odorant+++GO:0051384///response to glucocorticoid+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0060008///Sertoli cell differentiation+++GO:0008584///male gonad development+++GO:0007154///cell communication+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0006508///proteolysis+++GO:0022617///extracellular matrix disassembly+++GO:0014070///response to organic cyclic compound+++GO:0034698///response to gonadotropin+++GO:0007283///spermatogenesis+++GO:0048102///autophagic cell death+++GO:0009749///response to glucose+++GO:0021675///nerve development+++GO:0045616///regulation of keratinocyte differentiation+++GO:0009267///cellular response to starvation+++GO:0046697///decidualization+++GO:0010259///multicellular organism aging","cathepsin V","[CATL2_HUMAN|Reviewed]RecName: Full=Cathepsin L2; EC=3.4.22.43; AltName: Full=Cathepsin U; AltName: Full=Cathepsin V; Flags: Precursor;+++[A0A024R141_HUMAN|Unreviewed]SubName: Full=Cathepsin L2, isoform CRA_a {ECO:0000313|EMBL:EAW58832.1};+++[B2R717_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93235, highly similar to Homo sapiens cathepsin L2 (CTSL2), mRNA {ECO:0000313|EMBL:BAG35664.1};"]
[151742,"'PPM1L'",272,222,165.02,219.673333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0043169///cation binding+++GO:0003824///catalytic activity+++GO:0004722///protein serine/threonine phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0000165///MAPK cascade+++GO:0030148///sphingolipid biosynthetic process","protein phosphatase, Mg2+/Mn2+ dependent 1L","[PPM1L_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1L; EC=3.1.3.16; AltName: Full=Protein phosphatase 1-like; AltName: Full=Protein phosphatase 2C isoform epsilon; Short=PP2C-epsilon;"]
[151963,"'MB21D2'",64,54,56,58,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding",null,"Mab-21 domain containing 2","[M21D2_HUMAN|Reviewed]RecName: Full=Protein MB21D2; AltName: Full=Mab-21 domain-containing protein 2;"]
[1525,"'CXADR'",929.99,1080.05,859,956.346666666667,"05416///Viral myocarditis",{"$nulls":3},"GO:0030175///filopodium+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0030054///cell junction+++GO:0005923///bicellular tight junction+++GO:0005913///cell-cell adherens junction+++GO:0044297///cell body+++GO:0005912///adherens junction+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction+++GO:0016021///integral component of membrane+++GO:0031594///neuromuscular junction+++GO:0005887///integral component of plasma membrane+++GO:0043005///neuron projection+++GO:0045121///membrane raft+++GO:0016327///apicolateral plasma membrane+++GO:0005654///nucleoplasm+++GO:0005576///extracellular region+++GO:0001669///acrosomal vesicle+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc","GO:0001618///virus receptor activity+++GO:0005102///signaling receptor binding+++GO:0050839///cell adhesion molecule binding+++GO:0005178///integrin binding+++GO:0086082///cell adhesive protein binding involved in AV node cell-bundle of His cell communication+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0071253///connexin binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding","GO:0031532///actin cytoskeleton reorganization+++GO:0007005///mitochondrion organization+++GO:0046718///viral entry into host cell+++GO:0016032///viral process+++GO:0051607///defense response to virus+++GO:0034109///homotypic cell-cell adhesion+++GO:0086067///AV node cell to bundle of His cell communication+++GO:0086072///AV node cell-bundle of His cell adhesion involved in cell communication+++GO:0046629///gamma-delta T cell activation+++GO:0070633///transepithelial transport+++GO:0010669///epithelial structure maintenance+++GO:0098609///cell-cell adhesion+++GO:0098904///regulation of AV node cell action potential+++GO:0050900///leukocyte migration+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0008354///germ cell migration+++GO:0045216///cell-cell junction organization+++GO:0030593///neutrophil chemotaxis+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007507///heart development+++GO:0007155///cell adhesion+++GO:0048739///cardiac muscle fiber development+++GO:0050776///regulation of immune response","CXADR, Ig-like cell adhesion molecule","[CXAR_HUMAN|Reviewed]RecName: Full=Coxsackievirus and adenovirus receptor; Short=CAR; Short=hCAR; AltName: Full=CVB3-binding protein; AltName: Full=Coxsackievirus B-adenovirus receptor; AltName: Full=HCVADR; Flags: Precursor;"]
[152815,"'THAP6'",165.01,181,155,167.003333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015630///microtubule cytoskeleton","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","THAP domain containing 6","[THAP6_HUMAN|Reviewed]RecName: Full=THAP domain-containing protein 6;+++[A0A024RDF9_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_b {ECO:0000313|EMBL:EAX05735.1};+++[D6RBC3_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_e {ECO:0000313|EMBL:EAX05734.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000424255};+++[D6RC19_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000422402}; Flags: Fragment;+++[D6REL7_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426760};+++[D6REQ5_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_d {ECO:0000313|EMBL:EAX05733.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000424949};+++[D6RF27_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426698};+++[D6RFK7_HUMAN|Unreviewed]SubName: Full=THAP domain containing 6, isoform CRA_a {ECO:0000313|EMBL:EAX05730.1}; SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000426581};+++[D6RJG2_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000425646}; Flags: Fragment;"]
[153527,"'ZMAT2'",760,920,1024,901.333333333333,"03040///Spliceosome",{"$nulls":3},"GO:0071005///U2-type precatalytic spliceosome+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome","zinc finger matrin-type 2","[ZMAT2_HUMAN|Reviewed]RecName: Full=Zinc finger matrin-type protein 2;+++[R4GMX9_HUMAN|Unreviewed]SubName: Full=Zinc finger matrin-type protein 2 {ECO:0000313|Ensembl:ENSP00000473397}; Flags: Fragment;+++[R4GNG8_HUMAN|Unreviewed]SubName: Full=Zinc finger matrin-type protein 2 {ECO:0000313|Ensembl:ENSP00000473644}; Flags: Fragment;"]
[153768,"'PRELID2'",41,36,44,40.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005758///mitochondrial intermembrane space","GO:1990050///phosphatidic acid transporter activity","GO:0015914///phospholipid transport","PRELI domain containing 2","[PRLD2_HUMAN|Reviewed]RecName: Full=PRELI domain-containing protein 2;+++[D6RAB6_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422789};"]
[154743,"'BMT2'",106,99,74,93,{"$nulls":4},"GO:0005730///nucleolus+++GO:0140007///KICSTOR complex+++GO:1990130///GATOR1 complex","GO:0008168///methyltransferase activity+++GO:0016433///rRNA (adenine) methyltransferase activity+++GO:0016740///transferase activity+++GO:1904047///S-adenosyl-L-methionine binding","GO:0034198///cellular response to amino acid starvation+++GO:0031167///rRNA methylation+++GO:1904262///negative regulation of TORC1 signaling+++GO:0032259///methylation","base methyltransferase of 25S rRNA 2 homolog","[SAMTR_HUMAN|Reviewed]RecName: Full=S-adenosylmethionine sensor upstream of mTORC1 {ECO:0000255|HAMAP-Rule:MF_03044, ECO:0000303|PubMed:29123071}; AltName: Full=Probable methyltransferase BMT2 homolog {ECO:0000255|HAMAP-Rule:MF_03044}; EC=2.1.1.- {ECO:0000255|HAMAP-Rule:MF_03044};+++[B4DST1_HUMAN|Unreviewed]RecName: Full=S-adenosylmethionine sensor upstream of mTORC1 {ECO:0000256|HAMAP-Rule:MF_03044}; AltName: Full=Probable methyltransferase BMT2 homolog {ECO:0000256|HAMAP-Rule:MF_03044}; EC=2.1.1.- {ECO:0000256|HAMAP-Rule:MF_03044};+++[H0Y6Y0_HUMAN|Unreviewed]SubName: Full=S-adenosylmethionine sensor upstream of mTORC1 {ECO:0000313|Ensembl:ENSP00000408654}; Flags: Fragment;"]
[155066,"'ATP6V0E2'",2116,2197,2458,2257,"04145///Phagosome+++05110///Vibrio cholerae infection+++05323///Rheumatoid arthritis+++01100///Metabolic pathways+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04966///Collecting duct acid secretion+++04721///Synaptic vesicle cycle+++00190///Oxidative phosphorylation+++05165///Human papillomavirus infection",null,"M00160///V-type ATPase, eukaryotes",null,"GO:0010008///endosome membrane+++GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0016021///integral component of membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0016020///membrane","GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0042625///ATPase coupled ion transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0015078///proton transmembrane transporter activity","GO:0006811///ion transport+++GO:0033572///transferrin transport+++GO:0055085///transmembrane transport+++GO:0007035///vacuolar acidification+++GO:0034220///ion transmembrane transport+++GO:0016241///regulation of macroautophagy+++GO:1902600///proton transmembrane transport+++GO:0008286///insulin receptor signaling pathway+++GO:0015991///ATP hydrolysis coupled proton transport","ATPase H+ transporting V0 subunit e2","[VA0E2_HUMAN|Reviewed]RecName: Full=V-type proton ATPase subunit e 2; Short=V-ATPase subunit e 2; AltName: Full=Lysosomal 9 kDa H(+)-transporting ATPase V0 subunit e2; AltName: Full=Vacuolar proton pump subunit e 2;+++[E9PAS2_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit e 2 {ECO:0000313|Ensembl:ENSP00000411672};+++[F8WDM2_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit e 2 {ECO:0000313|Ensembl:ENSP00000420012};"]
[157638,"'FAM84B'",6853,7477,5943,6757.66666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding",null,"family with sequence similarity 84 member B","[FA84B_HUMAN|Reviewed]RecName: Full=Protein FAM84B; AltName: Full=Breast cancer membrane protein 101; AltName: Full=Protein NSE2;"]
[158,"'ADSL'",735,781,837,784.333333333333,"00250///Alanine, aspartate and glutamate metabolism+++01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++00230///Purine metabolism","H00197///Adenylosuccinate lyase deficiency","M00048///Inosine monophosphate biosynthesis, PRPP + glutamine => IMP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R04559///1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase   1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide+++R01083///N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)   N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP","GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0016829///lyase activity+++GO:0004018///N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity+++GO:0004056///argininosuccinate lyase activity+++GO:0070626///(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0044208///'de novo' AMP biosynthetic process+++GO:0042594///response to starvation+++GO:0051262///protein tetramerization+++GO:0009060///aerobic respiration+++GO:0006526///arginine biosynthetic process+++GO:0007626///locomotory behavior+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006163///purine nucleotide metabolic process+++GO:0000050///urea cycle+++GO:0006520///cellular amino acid metabolic process+++GO:0001666///response to hypoxia+++GO:0019676///ammonia assimilation cycle+++GO:0008652///cellular amino acid biosynthetic process+++GO:0009791///post-embryonic development+++GO:0006167///AMP biosynthetic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0042450///arginine biosynthetic process via ornithine+++GO:0009152///purine ribonucleotide biosynthetic process+++GO:0007584///response to nutrient+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0014850///response to muscle activity","adenylosuccinate lyase","[PUR8_HUMAN|Reviewed]RecName: Full=Adenylosuccinate lyase {ECO:0000303|PubMed:8404037}; Short=ADSL {ECO:0000303|PubMed:8404037}; Short=ASL; EC=4.3.2.2 {ECO:0000269|PubMed:16973378, ECO:0000269|PubMed:22812634}; AltName: Full=Adenylosuccinase {ECO:0000303|PubMed:9266401}; Short=ASase;+++[A0A096LNT0_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485202}; Flags: Fragment;+++[A0A096LNY4_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485286};+++[A0A096LNY5_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485288}; Flags: Fragment;+++[A0A096LNY6_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485289}; Flags: Fragment;+++[A0A096LP72_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485437};+++[A0A096LP76_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485443}; Flags: Fragment;+++[A0A096LP92_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485462}; Flags: Fragment;+++[A0A096LPA2_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485477}; Flags: Fragment;+++[A0A0A6YY92_HUMAN|Unreviewed]RecName: Full=Adenylosuccinate lyase {ECO:0000256|RuleBase:RU361172}; Short=ASL {ECO:0000256|RuleBase:RU361172}; EC=4.3.2.2 {ECO:0000256|RuleBase:RU361172}; AltName: Full=Adenylosuccinase {ECO:0000256|RuleBase:RU361172};+++[A0A1B0GTG9_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000489696}; Flags: Fragment;+++[A0A1B0GTJ7_HUMAN|Unreviewed]RecName: Full=Adenylosuccinate lyase {ECO:0000256|RuleBase:RU361172}; Short=ASL {ECO:0000256|RuleBase:RU361172}; EC=4.3.2.2 {ECO:0000256|RuleBase:RU361172}; AltName: Full=Adenylosuccinase {ECO:0000256|RuleBase:RU361172};+++[A0A1B0GWF8_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000490909}; Flags: Fragment;+++[A0A1B0GWJ0_HUMAN|Unreviewed]RecName: Full=Adenylosuccinate lyase {ECO:0000256|RuleBase:RU361172}; Short=ASL {ECO:0000256|RuleBase:RU361172}; EC=4.3.2.2 {ECO:0000256|RuleBase:RU361172}; AltName: Full=Adenylosuccinase {ECO:0000256|RuleBase:RU361172};+++[B4DEP1_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000485073}; SubName: Full=cDNA FLJ59852, highly similar to Adenylosuccinate lyase {ECO:0000313|EMBL:BAG57152.1};+++[V9GY96_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase {ECO:0000313|Ensembl:ENSP00000476535}; Flags: Fragment;+++[X5D2Z4_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase isoform A {ECO:0000313|EMBL:AHW56659.1};+++[X5D7V4_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase isoform E {ECO:0000313|EMBL:AHW56680.1};+++[X5D7W4_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase isoform C {ECO:0000313|EMBL:AHW56695.1};+++[X5D8S6_HUMAN|Unreviewed]RecName: Full=Adenylosuccinate lyase {ECO:0000256|RuleBase:RU361172}; Short=ASL {ECO:0000256|RuleBase:RU361172}; EC=4.3.2.2 {ECO:0000256|RuleBase:RU361172}; AltName: Full=Adenylosuccinase {ECO:0000256|RuleBase:RU361172}; Flags: Fragment;+++[X5DP48_HUMAN|Unreviewed]SubName: Full=Adenylosuccinate lyase isoform D {ECO:0000313|EMBL:AHW56646.1};"]
[158427,"'TSTD2'",398,345,316,353,"03015///mRNA surveillance pathway+++03013///RNA transport+++03040///Spliceosome",null,"M00399///Cap binding complex",null,"GO:0005575///cellular_component","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003674///molecular_function","GO:0008150///biological_process","thiosulfate sulfurtransferase like domain containing 2","[TSTD2_HUMAN|Reviewed]RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2; AltName: Full=Rhodanese domain-containing protein 2;+++[A0A0S2Z5Z0_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase-like domain containing 2 isoform 1 {ECO:0000313|EMBL:ALQ34335.1}; Flags: Fragment;+++[A0A0S2Z608_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase-like domain containing 2 isoform 2 {ECO:0000313|EMBL:ALQ34336.1};+++[A0A1Y8ELM0_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000364308}; Flags: Fragment;+++[Q5T7X0_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000364315};+++[Q8TBB8_HUMAN|Unreviewed]SubName: Full=C9orf97 protein {ECO:0000313|EMBL:AAH22958.1};"]
[159091,"'FAM122C'",16,14,17.89,15.9633333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","family with sequence similarity 122C","[F222C_HUMAN|Reviewed]RecName: Full=Protein FAM122C;+++[A0A087WU98_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000485120};+++[A0A2R8Y466_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000493672};+++[A0A2R8Y4Q6_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000493993};+++[A0A2R8Y5U9_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000495073};+++[A0A2R8Y6Q5_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000495698};+++[A0A2R8Y7I3_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000496039};+++[A0A2R8Y7S4_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000496338};+++[A0A2R8YFJ9_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000496521};+++[A0A2R8YFQ2_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000495335};+++[A0A2R8YGQ0_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000496258};+++[B3KQY3_HUMAN|Unreviewed]SubName: Full=Protein FAM122C {ECO:0000313|Ensembl:ENSP00000495200}; SubName: Full=cDNA FLJ33292 fis, clone BNGH42000130, weakly similar to Homo sapiens beta glucuronidase isoform {ECO:0000313|EMBL:BAG52195.1};+++[B4DI96_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61273 {ECO:0000313|EMBL:BAG58408.1};+++[D3DTG4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX11747.1};+++[Q6P187_HUMAN|Unreviewed]SubName: Full=FAM122C protein {ECO:0000313|EMBL:AAH65225.1};"]
[1602,"'DACH1'",287,287,231,268.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0016251///RNA polymerase II general transcription initiation factor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0001967///suckling behavior+++GO:0006366///transcription by RNA polymerase II+++GO:0030336///negative regulation of cell migration+++GO:0060244///negative regulation of cell proliferation involved in contact inhibition+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:0008283///cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007585///respiratory gaseous exchange+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0046545///development of primary female sexual characteristics+++GO:0033262///regulation of nuclear cell cycle DNA replication","dachshund family transcription factor 1","[DACH1_HUMAN|Reviewed]RecName: Full=Dachshund homolog 1; Short=Dach1;+++[A0A087WY66_HUMAN|Unreviewed]SubName: Full=Dachshund homolog 1 {ECO:0000313|Ensembl:ENSP00000481551};+++[A0A087WZA7_HUMAN|Unreviewed]SubName: Full=Dachshund homolog 1 {ECO:0000313|Ensembl:ENSP00000482493};"]
[160762,"'CCDC63'",1,6,0,2.33333333333333,{"$nulls":4},"GO:0005930///axoneme",null,"GO:0036158///outer dynein arm assembly+++GO:0007286///spermatid development+++GO:0007283///spermatogenesis+++GO:0003341///cilium movement+++GO:0030154///cell differentiation","coiled-coil domain containing 63","[CCD63_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 63 {ECO:0000312|HGNC:HGNC:26669};+++[G3V217_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 63, isoform CRA_b {ECO:0000313|EMBL:EAW97942.1}; SubName: Full=Coiled-coil domain-containing protein 63 {ECO:0000313|Ensembl:ENSP00000450217};"]
[1613,"'DAPK3'",1959,2441,2465,2288.33333333333,"05200///Pathways in cancer+++05219///Bladder cancer+++04140///Autophagy - animal","H00022///Bladder cancer",null,null,"GO:0005634///nucleus+++GO:0016605///PML body+++GO:0005884///actin filament+++GO:0045121///membrane raft+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0008140///cAMP response element binding protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0043522///leucine zipper domain binding+++GO:0004672///protein kinase activity+++GO:0008022///protein C-terminus binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0017048///Rho GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding","GO:2000145///regulation of cell motility+++GO:0007346///regulation of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006325///chromatin organization+++GO:0007088///regulation of mitotic nuclear division+++GO:0017148///negative regulation of translation+++GO:0006468///protein phosphorylation+++GO:0006417///regulation of translation+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:0006940///regulation of smooth muscle contraction+++GO:0051893///regulation of focal adhesion assembly+++GO:0035556///intracellular signal transduction+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0030335///positive regulation of cell migration+++GO:2001241///positive regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0097190///apoptotic signaling pathway+++GO:0043519///regulation of myosin II filament organization+++GO:0008360///regulation of cell shape+++GO:0030182///neuron differentiation+++GO:0006915///apoptotic process+++GO:0010506///regulation of autophagy+++GO:0016310///phosphorylation+++GO:0071346///cellular response to interferon-gamma+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0046777///protein autophosphorylation","death associated protein kinase 3","[DAPK3_HUMAN|Reviewed]RecName: Full=Death-associated protein kinase 3; Short=DAP kinase 3; EC=2.7.11.1 {ECO:0000269|PubMed:10356987, ECO:0000269|PubMed:11384979, ECO:0000269|PubMed:11781833, ECO:0000269|PubMed:15096528, ECO:0000269|PubMed:17126281, ECO:0000269|PubMed:18995835}; AltName: Full=DAP-like kinase; Short=Dlk; AltName: Full=MYPT1 kinase; AltName: Full=Zipper-interacting protein kinase; Short=ZIP-kinase;+++[B3KNJ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14684 fis, clone NT2RP2004933, highly similar to Death-associated protein kinase 3 {ECO:0000313|EMBL:BAG51355.1};+++[M0QYW5_HUMAN|Unreviewed]SubName: Full=Death-associated protein kinase 3 {ECO:0000313|Ensembl:ENSP00000470115}; Flags: Fragment;+++[M0QYY8_HUMAN|Unreviewed]SubName: Full=Death-associated protein kinase 3 {ECO:0000313|Ensembl:ENSP00000470168}; Flags: Fragment;+++[M0R0D0_HUMAN|Unreviewed]SubName: Full=Death-associated protein kinase 3 {ECO:0000313|Ensembl:ENSP00000471154}; Flags: Fragment;"]
[161882,"'ZFPM1'",525,661,641,609,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0008134///transcription factor binding+++GO:0046872///metal ion binding","GO:0030218///erythrocyte differentiation+++GO:0071733///transcriptional activation by promoter-enhancer looping+++GO:0060377///negative regulation of mast cell differentiation+++GO:0010724///regulation of definitive erythrocyte differentiation+++GO:0003151///outflow tract morphogenesis+++GO:0045403///negative regulation of interleukin-4 biosynthetic process+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0030220///platelet formation+++GO:0060319///primitive erythrocyte differentiation+++GO:0032642///regulation of chemokine production+++GO:0003192///mitral valve formation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0003195///tricuspid valve formation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030851///granulocyte differentiation+++GO:0048872///homeostasis of number of cells+++GO:0032091///negative regulation of protein binding+++GO:0003181///atrioventricular valve morphogenesis+++GO:0060413///atrial septum morphogenesis+++GO:0035162///embryonic hemopoiesis+++GO:0007507///heart development+++GO:0060318///definitive erythrocyte differentiation+++GO:0002295///T-helper cell lineage commitment+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007596///blood coagulation+++GO:0035855///megakaryocyte development+++GO:0030219///megakaryocyte differentiation+++GO:0060412///ventricular septum morphogenesis","zinc finger protein, FOG family member 1","[FOG1_HUMAN|Reviewed]RecName: Full=Zinc finger protein ZFPM1; AltName: Full=Friend of GATA protein 1; Short=FOG-1; Short=Friend of GATA 1; AltName: Full=Zinc finger protein 89A; AltName: Full=Zinc finger protein multitype 1;+++[A0A087WWQ0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFPM1 {ECO:0000313|Ensembl:ENSP00000480412}; SubName: Full=Zinc finger protein, multitype 1, isoform CRA_b {ECO:0000313|EMBL:EAW66807.1};+++[A0A087WZP1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFPM1 {ECO:0000313|Ensembl:ENSP00000482796}; SubName: Full=Zinc finger protein, multitype 1, isoform CRA_c {ECO:0000313|EMBL:EAW66808.1};+++[A0A087X1H8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFPM1 {ECO:0000313|Ensembl:ENSP00000484216};"]
[162466,"'PHOSPHO1'",8,23,20,17,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways",null,null,"R06871///Phosphocholine phosphohydrolase   Choline phosphate + H2O <=> Choline + Orthophosphate+++R06870///Phosphoethanolamine phosphohydrolase   Ethanolamine phosphate + H2O <=> Ethanolamine + Orthophosphate","GO:0031012///extracellular matrix+++GO:0005829///cytosol+++GO:0065010///extracellular membrane-bounded organelle","GO:0016462///pyrophosphatase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding+++GO:0052732///phosphoethanolamine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0052731///phosphocholine phosphatase activity","GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process+++GO:0016311///dephosphorylation+++GO:0030500///regulation of bone mineralization+++GO:0001958///endochondral ossification+++GO:0035630///bone mineralization involved in bone maturation","phosphoethanolamine/phosphocholine phosphatase","[PHOP1_HUMAN|Reviewed]RecName: Full=Phosphoethanolamine/phosphocholine phosphatase; EC=3.1.3.75;+++[D6RB58_HUMAN|Unreviewed]SubName: Full=Phosphoethanolamine/phosphocholine phosphatase {ECO:0000313|Ensembl:ENSP00000424406}; Flags: Fragment;+++[D6RHH9_HUMAN|Unreviewed]SubName: Full=Phosphoethanolamine/phosphocholine phosphatase {ECO:0000313|Ensembl:ENSP00000426095}; Flags: Fragment;+++[D6RIT6_HUMAN|Unreviewed]SubName: Full=Phosphoethanolamine/phosphocholine phosphatase {ECO:0000313|Ensembl:ENSP00000427397}; Flags: Fragment;+++[I3L4N1_HUMAN|Unreviewed]SubName: Full=Phosphoethanolamine/phosphocholine phosphatase {ECO:0000313|Ensembl:ENSP00000461392}; Flags: Fragment;"]
[162514,"'TRPV3'",18,15,22,18.3333333333333,"04750///Inflammatory mediator regulation of TRP channels",{"$nulls":3},"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0005886///plasma membrane","GO:0005262///calcium channel activity+++GO:0005261///cation channel activity+++GO:0005216///ion channel activity+++GO:0042802///identical protein binding","GO:0006811///ion transport+++GO:0009266///response to temperature stimulus+++GO:0055085///transmembrane transport+++GO:0009408///response to heat+++GO:0034220///ion transmembrane transport+++GO:0006816///calcium ion transport+++GO:0090280///positive regulation of calcium ion import+++GO:0070588///calcium ion transmembrane transport+++GO:0042636///negative regulation of hair cycle","transient receptor potential cation channel subfamily V member 3","[TRPV3_HUMAN|Reviewed]RecName: Full=Transient receptor potential cation channel subfamily V member 3; Short=TrpV3; AltName: Full=Vanilloid receptor-like 3; Short=VRL-3;+++[A0A087X170_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily V member 3 {ECO:0000313|Ensembl:ENSP00000483947};+++[B2KYM6_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily V member 3 {ECO:0000313|EMBL:ACA81614.1};+++[B7ZKP6_HUMAN|Unreviewed]SubName: Full=TRPV3 protein {ECO:0000313|EMBL:AAI43295.1};+++[B7ZKP9_HUMAN|Unreviewed]SubName: Full=TRPV3 protein {ECO:0000313|EMBL:AAI43300.1};+++[I3L0L5_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily V member 3 {ECO:0000313|Ensembl:ENSP00000458187};+++[I3L402_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily V member 3 {ECO:0000313|Ensembl:ENSP00000460856}; Flags: Fragment;+++[J3KPJ6_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily V member 3 {ECO:0000313|Ensembl:ENSP00000371338}; Flags: Fragment;+++[Q2M3L1_HUMAN|Unreviewed]SubName: Full=TRPV3 protein {ECO:0000313|EMBL:AAI43331.1}; SubName: Full=Transient receptor potential cation channel, subfamily V, member 3 {ECO:0000313|EMBL:AAI04869.1};"]
[162998,"'OR7D2'",0,1,1,0.666666666666667,"04740///Olfactory transduction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0007608///sensory perception of smell+++GO:0006355///regulation of transcription, DNA-templated","olfactory receptor family 7 subfamily D member 2","[OR7D2_HUMAN|Reviewed]RecName: Full=Olfactory receptor 7D2; AltName: Full=HTPCRH03; AltName: Full=Olfactory receptor 19-4; Short=OR19-4; AltName: Full=Olfactory receptor OR19-10;+++[A0A126GVY4_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};"]
[163590,"'TOR1AIP2'",740,637.38,572,649.793333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0001671///ATPase activator activity+++GO:0051117///ATPase binding+++GO:0005515///protein binding","GO:0032781///positive regulation of ATPase activity+++GO:0007029///endoplasmic reticulum organization+++GO:0090435///protein localization to nuclear envelope","torsin 1A interacting protein 2","[IFG15_HUMAN|Reviewed]RecName: Full=Torsin-1A-interacting protein 2, isoform IFRG15; AltName: Full=15 kDa interferon-responsive protein; Short=IFRG15;+++[TOIP2_HUMAN|Reviewed]RecName: Full=Torsin-1A-interacting protein 2; AltName: Full=Lumenal domain-like LAP1;+++[A0A024R957_HUMAN|Unreviewed]SubName: Full=Torsin A interacting protein 2, isoform CRA_b {ECO:0000313|EMBL:EAW91060.1};+++[A0A096LNM1_HUMAN|Unreviewed]SubName: Full=Torsin-1A-interacting protein 2, isoform IFRG15 {ECO:0000313|Ensembl:ENSP00000485107}; Flags: Fragment;"]
[163732,"'CITED4'",144,116,155,138.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043627///response to estrogen+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated","Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4","[CITE4_HUMAN|Reviewed]RecName: Full=Cbp/p300-interacting transactivator 4; AltName: Full=MSG1-related protein 2; Short=MRG-2;"]
[1642,"'DDB1'",5630,5726,5371,5575.66666666667,"05161///Hepatitis B+++04120///Ubiquitin mediated proteolysis+++05203///Viral carcinogenesis+++03420///Nucleotide excision repair","H01428///Xeroderma pigmentosum (XP)+++H00403///Disorders of nucleotide excision repair","M00386///Cul4-DDB1-CSA complex+++M00385///Cul4-DDB1-DDB2 complex",null,"GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0005615///extracellular space+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex","GO:0097602///cullin family protein binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0003684///damaged DNA binding+++GO:0030674///protein binding, bridging+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0071987///WD40-repeat domain binding","GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:1902188///positive regulation of viral release from host cell+++GO:0035518///histone H2A monoubiquitination+++GO:0046726///positive regulation by virus of viral protein levels in host cell+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0043687///post-translational protein modification+++GO:0070911///global genome nucleotide-excision repair+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0010498///proteasomal protein catabolic process+++GO:0006281///DNA repair+++GO:0045070///positive regulation of viral genome replication+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0043066///negative regulation of apoptotic process+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006289///nucleotide-excision repair+++GO:0051702///interaction with symbiont+++GO:0016567///protein ubiquitination+++GO:0070914///UV-damage excision repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0045732///positive regulation of protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016032///viral process+++GO:0016055///Wnt signaling pathway","damage specific DNA binding protein 1","[DDB1_HUMAN|Reviewed]RecName: Full=DNA damage-binding protein 1; AltName: Full=DDB p127 subunit; AltName: Full=DNA damage-binding protein a; Short=DDBa; AltName: Full=Damage-specific DNA-binding protein 1; AltName: Full=HBV X-associated protein 1; Short=XAP-1; AltName: Full=UV-damaged DNA-binding factor; AltName: Full=UV-damaged DNA-binding protein 1; Short=UV-DDB 1; AltName: Full=XPE-binding factor; Short=XPE-BF; AltName: Full=Xeroderma pigmentosum group E-complementing protein; Short=XPCe;+++[F5GWI0_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 1 {ECO:0000313|Ensembl:ENSP00000441825}; Flags: Fragment;+++[F5GY55_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 1 {ECO:0000313|Ensembl:ENSP00000440269};+++[F5GYG8_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 1 {ECO:0000313|Ensembl:ENSP00000440660}; Flags: Fragment;+++[F5GZY8_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 1 {ECO:0000313|Ensembl:ENSP00000444105}; Flags: Fragment;+++[F5H198_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 1 {ECO:0000313|Ensembl:ENSP00000445844}; Flags: Fragment;+++[F5H2L3_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 1 {ECO:0000313|Ensembl:ENSP00000445554}; Flags: Fragment;"]
[165082,"'ADGRF3'",6,7,3,5.33333333333333,"00565///Ether lipid metabolism+++01100///Metabolic pathways+++00440///Phosphonate and phosphinate metabolism+++00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites",null,"M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE","R02057///CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine+++R06364///CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine+++R04920///CMP-2-aminoethylphosphonate:1,2-diacylglycerol (2-aminoethylphosphonyl)transferase CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate+++R07384///O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine","GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway","adhesion G protein-coupled receptor F3","[AGRF3_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor F3; AltName: Full=G-protein coupled receptor 113; AltName: Full=G-protein coupled receptor PGR23; Flags: Precursor;+++[C9JSE8_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor F3 {ECO:0000313|Ensembl:ENSP00000409595}; Flags: Fragment;+++[D6W540_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 113, isoform CRA_b {ECO:0000313|EMBL:EAX00698.1};+++[F8WE87_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor F3 {ECO:0000313|Ensembl:ENSP00000394162};"]
[165545,"'DQX1'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0005524///ATP binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome","DEAQ-box RNA dependent ATPase 1","[DQX1_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DQX1; EC=3.6.4.12; AltName: Full=DEAQ box polypeptide 1;+++[C9J0W1_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DQX1 {ECO:0000313|Ensembl:ENSP00000392969}; Flags: Fragment;+++[H7BZE3_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DQX1 {ECO:0000313|Ensembl:ENSP00000389196}; Flags: Fragment;"]
[166793,"'ZBTB49'",74,54,57,61.6666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton+++GO:0005654///nucleoplasm","GO:0008134///transcription factor binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0001223///transcription coactivator binding+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation+++GO:0007049///cell cycle","zinc finger and BTB domain containing 49","[ZBT49_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 49; AltName: Full=Zinc finger protein 509;+++[D6RB16_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 49 {ECO:0000313|Ensembl:ENSP00000424525};+++[D6RC96_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 49 {ECO:0000313|Ensembl:ENSP00000422321};+++[D6RJ00_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 49 {ECO:0000313|Ensembl:ENSP00000425747}; Flags: Fragment;+++[H0Y8P2_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 49 {ECO:0000313|Ensembl:ENSP00000421654}; Flags: Fragment;+++[H0YAD4_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 49 {ECO:0000313|Ensembl:ENSP00000426765}; Flags: Fragment;+++[Q32MK9_HUMAN|Unreviewed]SubName: Full=HCG2039195, isoform CRA_a {ECO:0000313|EMBL:EAW82433.1}; SubName: Full=HCG39122 {ECO:0000313|EMBL:EAW82436.1}; SubName: Full=ZNF509 protein {ECO:0000313|EMBL:AAI09089.1};"]
[167359,"'NIM1K'",39,35,33,35.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031588///nucleotide-activated protein kinase complex+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0016301///kinase activity","GO:0042149///cellular response to glucose starvation+++GO:0016310///phosphorylation+++GO:0032007///negative regulation of TOR signaling+++GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction","NIM1 serine/threonine protein kinase","[NIM1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase NIM1; EC=2.7.11.1; AltName: Full=NIM1 serine/threonine-protein kinase;"]
[168975,"'CNBD1'",0,1,2,1,{"$nulls":4},"GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0005730///nucleolus","GO:0042802///identical protein binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0003697///single-stranded DNA binding+++GO:0003727///single-stranded RNA binding","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination","cyclic nucleotide binding domain containing 1","[CNBD1_HUMAN|Reviewed]RecName: Full=Cyclic nucleotide-binding domain-containing protein 1;+++[A0A087WTB2_HUMAN|Unreviewed]SubName: Full=Cyclic nucleotide-binding domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000477731};+++[H0YAN5_HUMAN|Unreviewed]SubName: Full=Cyclic nucleotide-binding domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000427742}; Flags: Fragment;+++[H0YC59_HUMAN|Unreviewed]SubName: Full=Cyclic nucleotide-binding domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000430986}; Flags: Fragment;"]
[169611,"'OLFML2A'",115,86,63,88,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031012///extracellular matrix","GO:0050840///extracellular matrix binding+++GO:0042803///protein homodimerization activity","GO:0030198///extracellular matrix organization","olfactomedin like 2A","[OLM2A_HUMAN|Reviewed]RecName: Full=Olfactomedin-like protein 2A; AltName: Full=Photomedin-1; Flags: Precursor;+++[Q5JTM7_HUMAN|Unreviewed]SubName: Full=Olfactomedin-like protein 2A {ECO:0000313|Ensembl:ENSP00000336425}; Flags: Fragment;"]
[170690,"'ADAMTS16'",857,1037,530,808,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0016787///hydrolase activity","GO:0006508///proteolysis+++GO:1902017///regulation of cilium assembly+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0048232///male gamete generation","ADAM metallopeptidase with thrombospondin type 1 motif 16","[ATS16_HUMAN|Reviewed]RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 16; Short=ADAM-TS 16; Short=ADAM-TS16; Short=ADAMTS-16; EC=3.4.24.-; Flags: Precursor;+++[B2G3Q1_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase with thrombospondin type 1 motif, 16 {ECO:0000313|EMBL:CAQ42983.1}; Flags: Fragment;+++[L8E9K8_HUMAN|Unreviewed]SubName: Full=Alternative protein ADAMTS16 {ECO:0000313|EMBL:CCQ43834.1};+++[Q2XQZ0_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 16 {ECO:0000313|Ensembl:ENSP00000421631}; SubName: Full=ADAMTS16s alternative splice form {ECO:0000313|EMBL:ABB70405.1};"]
[170960,"'ZNF721'",249,235,160,214.666666666667,"00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis+++02010///ABC transporters","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,"R05924///Phosphatidylethanolamine + G00141 <=> 1,2-Diacyl-sn-glycerol + G00151","GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 721","[ZN721_HUMAN|Reviewed]RecName: Full=Zinc finger protein 721;+++[B4E159_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 721 {ECO:0000313|Ensembl:ENSP00000423586}; SubName: Full=cDNA FLJ57767, moderately similar to Zinc finger protein 141 {ECO:0000313|EMBL:BAG64671.1};+++[D6RGC2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 721 {ECO:0000313|Ensembl:ENSP00000421325}; Flags: Fragment;+++[E5RGH0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 721 {ECO:0000313|Ensembl:ENSP00000430163};"]
[1734,"'DIO2'",1940,3641,3183,2921.33333333333,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005623///cell+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008430///selenium binding+++GO:0016491///oxidoreductase activity+++GO:0004800///thyroxine 5'-deiodinase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0001514///selenocysteine incorporation+++GO:0042446///hormone biosynthetic process+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process+++GO:0042404///thyroid hormone catabolic process+++GO:0042403///thyroid hormone metabolic process+++GO:0006590///thyroid hormone generation","iodothyronine deiodinase 2","[IOD2_HUMAN|Reviewed]RecName: Full=Type II iodothyronine deiodinase; EC=1.21.99.4; AltName: Full=5DII; AltName: Full=DIOII; AltName: Full=Type 2 DI; AltName: Full=Type-II 5'-deiodinase;+++[A0A024R6H2_HUMAN|Unreviewed]SubName: Full=Deiodinase, iodothyronine, type II {ECO:0000313|EMBL:EAW81324.1};+++[A0A024R6J8_HUMAN|Unreviewed]RecName: Full=Iodothyronine deiodinase {ECO:0000256|RuleBase:RU000676};+++[A0A0A0MTQ2_HUMAN|Unreviewed]RecName: Full=Iodothyronine deiodinase {ECO:0000256|RuleBase:RU000676};+++[A8K845_HUMAN|Unreviewed]RecName: Full=Iodothyronine deiodinase {ECO:0000256|RuleBase:RU000676};+++[G3V2A7_HUMAN|Unreviewed]SubName: Full=Type II iodothyronine deiodinase {ECO:0000313|Ensembl:ENSP00000450547};+++[G3V3A8_HUMAN|Unreviewed]RecName: Full=Iodothyronine deiodinase {ECO:0000256|RuleBase:RU000676}; Flags: Fragment;+++[H0YJ42_HUMAN|Unreviewed]SubName: Full=Type II iodothyronine deiodinase {ECO:0000313|Ensembl:ENSP00000450781}; Flags: Fragment;+++[H0YJQ8_HUMAN|Unreviewed]SubName: Full=Type II iodothyronine deiodinase {ECO:0000313|Ensembl:ENSP00000451971}; Flags: Fragment;+++[J3KQY5_HUMAN|Unreviewed]RecName: Full=Iodothyronine deiodinase {ECO:0000256|RuleBase:RU000676};+++[Q9C0K2_HUMAN|Unreviewed]RecName: Full=Iodothyronine deiodinase {ECO:0000256|RuleBase:RU000676}; Flags: Fragment;+++[Q9HCP7_HUMAN|Unreviewed]SubName: Full=Type II iodothyronine deiodinase {ECO:0000313|EMBL:BAB16839.1};+++[Q9NZL0_HUMAN|Unreviewed]RecName: Full=Iodothyronine deiodinase {ECO:0000256|RuleBase:RU000676}; Flags: Fragment;"]
[1740,"'DLG2'",18,15,19,17.3333333333333,"04530///Tight junction+++05165///Human papillomavirus infection+++04390///Hippo signaling pathway","H00473///Mitochondrial complex I deficiency",null,null,"GO:0044224///juxtaparanode region of axon+++GO:0005743///mitochondrial inner membrane+++GO:0043025///neuronal cell body+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane+++GO:0005634///nucleus+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:1990904///ribonucleoprotein complex+++GO:0030054///cell junction+++GO:0005739///mitochondrion+++GO:1904115///axon cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0016021///integral component of membrane+++GO:0005730///nucleolus","GO:0098919///structural constituent of postsynaptic density+++GO:0019900///kinase binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0004385///guanylate kinase activity+++GO:0046872///metal ion binding+++GO:0003727///single-stranded RNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0030165///PDZ domain binding+++GO:0046982///protein heterodimerization activity+++GO:0019903///protein phosphatase binding+++GO:0035255///ionotropic glutamate receptor binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding+++GO:0008022///protein C-terminus binding","GO:0097120///receptor localization to synapse+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0006351///transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045161///neuronal ion channel clustering+++GO:0010923///negative regulation of phosphatase activity+++GO:0007268///chemical synaptic transmission+++GO:0019233///sensory perception of pain+++GO:0043113///receptor clustering+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0099642///retrograde axonal protein transport+++GO:0009615///response to virus+++GO:0099641///anterograde axonal protein transport+++GO:0035865///cellular response to potassium ion+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0032197///transposition, RNA-mediated+++GO:0007399///nervous system development+++GO:0006310///DNA recombination","discs large MAGUK scaffold protein 2","[DLG2_HUMAN|Reviewed]RecName: Full=Disks large homolog 2; AltName: Full=Channel-associated protein of synapse-110; Short=Chapsyn-110; AltName: Full=Postsynaptic density protein PSD-93;+++[B7Z2T4_HUMAN|Unreviewed]SubName: Full=Disks large homolog 2 {ECO:0000313|Ensembl:ENSP00000435849}; SubName: Full=cDNA FLJ60066, highly similar to Discs large homolog 2 {ECO:0000313|EMBL:BAH11970.1};+++[E9PN83_HUMAN|Unreviewed]SubName: Full=Disks large homolog 2 {ECO:0000313|Ensembl:ENSP00000432894};"]
[1778,"'DYNC1H1'",10325,10674,7586,9528.33333333333,"04145///Phagosome+++04962///Vasopressin-regulated water reabsorption+++05132///Salmonella infection","H00455///Spinal muscular atrophy (SMA)+++H00264///Charcot-Marie-Tooth disease (CMT)+++H00773///Autosomal dominant mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0035578///azurophil granule lumen+++GO:0005868///cytoplasmic dynein complex+++GO:0016020///membrane+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0030286///dynein complex+++GO:0005576///extracellular region+++GO:0030175///filopodium+++GO:0005874///microtubule","GO:0051959///dynein light intermediate chain binding+++GO:0003777///microtubule motor activity+++GO:0005524///ATP binding+++GO:0045505///dynein intermediate chain binding+++GO:0045503///dynein light chain binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007018///microtubule-based movement+++GO:0051293///establishment of spindle localization+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0032388///positive regulation of intracellular transport+++GO:0051301///cell division+++GO:0031122///cytoplasmic microtubule organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0043312///neutrophil degranulation+++GO:0007052///mitotic spindle organization+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0072382///minus-end-directed vesicle transport along microtubule+++GO:0034063///stress granule assembly+++GO:1905832///positive regulation of spindle assembly+++GO:0090235///regulation of metaphase plate congression+++GO:0060236///regulation of mitotic spindle organization+++GO:0007049///cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle","dynein cytoplasmic 1 heavy chain 1","[DYHC1_HUMAN|Reviewed]RecName: Full=Cytoplasmic dynein 1 heavy chain 1; AltName: Full=Cytoplasmic dynein heavy chain 1; AltName: Full=Dynein heavy chain, cytosolic;+++[A0A2R8Y542_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000494189}; Flags: Fragment;+++[A0A2R8Y5T0_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000495022}; Flags: Fragment;+++[A0A2R8Y6H2_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000495220}; Flags: Fragment;+++[A0A2R8Y6I5_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000495356}; Flags: Fragment;+++[A0A2R8Y706_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000495944}; Flags: Fragment;+++[A0A2R8YFZ7_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000495528}; Flags: Fragment;+++[A0A2R8YGC7_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000495884}; Flags: Fragment;+++[H0YJ21_HUMAN|Unreviewed]SubName: Full=Cytoplasmic dynein 1 heavy chain 1 {ECO:0000313|Ensembl:ENSP00000450674}; Flags: Fragment;+++[Q6P2H7_HUMAN|Unreviewed]SubName: Full=DYNC1H1 protein {ECO:0000313|EMBL:AAH64521.1};+++[Q92862_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain {ECO:0000313|EMBL:AAC50701.1}; Flags: Fragment;"]
[1785,"'DNM2'",4931,4978,5326,5078.33333333333,"04144///Endocytosis+++04072///Phospholipase D signaling pathway+++04961///Endocrine and other factor-regulated calcium reabsorption+++04721///Synaptic vesicle cycle+++05100///Bacterial invasion of epithelial cells","H00606///Early infantile epileptic encephalopathy+++H00264///Charcot-Marie-Tooth disease (CMT)+++H00865///Lethal congenital contractural syndrome (LCCS)+++H00700///Centronuclear myopathy",null,null,"GO:0030666///endocytic vesicle membrane+++GO:0042995///cell projection+++GO:0005813///centrosome+++GO:0000139///Golgi membrane+++GO:0005905///clathrin-coated pit+++GO:0099092///postsynaptic density, intracellular component+++GO:0030027///lamellipodium+++GO:0032587///ruffle membrane+++GO:0030424///axon+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0030670///phagocytic vesicle membrane+++GO:0005737///cytoplasm+++GO:0045211///postsynaptic membrane+++GO:0001917///photoreceptor inner segment+++GO:0030426///growth cone+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0044327///dendritic spine head+++GO:0005794///Golgi apparatus+++GO:0098978///glutamatergic synapse+++GO:0005802///trans-Golgi network+++GO:0001891///phagocytic cup+++GO:0043197///dendritic spine+++GO:0014069///postsynaptic density+++GO:0030496///midbody+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0005768///endosome+++GO:0098844///postsynaptic endocytic zone membrane+++GO:0045202///synapse+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0005874///microtubule+++GO:0030054///cell junction+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0098793///presynapse+++GO:0031410///cytoplasmic vesicle","GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding+++GO:0000166///nucleotide binding+++GO:0031749///D2 dopamine receptor binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0016787///hydrolase activity+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0017124///SH3 domain binding+++GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0050998///nitric-oxide synthase binding+++GO:0008017///microtubule binding","GO:0009416///response to light stimulus+++GO:0006893///Golgi to plasma membrane transport+++GO:0071732///cellular response to nitric oxide+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0071481///cellular response to X-ray+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0048488///synaptic vesicle endocytosis+++GO:1902856///negative regulation of non-motile cilium assembly+++GO:1903351///cellular response to dopamine+++GO:0043065///positive regulation of apoptotic process+++GO:0061024///membrane organization+++GO:1903526///negative regulation of membrane tubulation+++GO:0006897///endocytosis+++GO:2000370///positive regulation of clathrin-dependent endocytosis+++GO:0050803///regulation of synapse structure or activity+++GO:0042220///response to cocaine+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0007165///signal transduction+++GO:0006909///phagocytosis+++GO:0044351///macropinocytosis+++GO:0071245///cellular response to carbon monoxide+++GO:0006898///receptor-mediated endocytosis+++GO:0006355///regulation of transcription, DNA-templated+++GO:1903408///positive regulation of sodium:potassium-exchanging ATPase activity+++GO:0033572///transferrin transport+++GO:0035904///aorta development+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0035020///regulation of Rac protein signal transduction+++GO:0060976///coronary vasculature development+++GO:0048489///synaptic vesicle transport+++GO:0003281///ventricular septum development+++GO:0048812///neuron projection morphogenesis+++GO:0045807///positive regulation of endocytosis+++GO:0002031///G protein-coupled receptor internalization+++GO:0031623///receptor internalization+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0007283///spermatogenesis+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0050766///positive regulation of phagocytosis+++GO:1903358///regulation of Golgi organization+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0030516///regulation of axon extension+++GO:0098884///postsynaptic neurotransmitter receptor internalization+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","dynamin 2","[DYN2_HUMAN|Reviewed]RecName: Full=Dynamin-2; EC=3.6.5.5;+++[A0A024R7C9_HUMAN|Unreviewed]SubName: Full=Dynamin 2, isoform CRA_b {ECO:0000313|EMBL:EAW84151.1};+++[K7EMQ3_HUMAN|Unreviewed]SubName: Full=Dynamin-2 {ECO:0000313|Ensembl:ENSP00000466603}; Flags: Fragment;+++[K7EMR9_HUMAN|Unreviewed]SubName: Full=Dynamin-2 {ECO:0000313|Ensembl:ENSP00000466621}; Flags: Fragment;+++[K7ENE7_HUMAN|Unreviewed]SubName: Full=Dynamin-2 {ECO:0000313|Ensembl:ENSP00000466914}; Flags: Fragment;+++[K7EPK9_HUMAN|Unreviewed]SubName: Full=Dynamin-2 {ECO:0000313|Ensembl:ENSP00000467430}; Flags: Fragment;+++[Q8N1K8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40556 fis, clone THYMU2002583, highly similar to DYNAMIN 2 {ECO:0000313|EMBL:BAC05190.1};+++[Q9UPH5_HUMAN|Unreviewed]SubName: Full=Dynamin II {ECO:0000313|EMBL:AAD23603.1}; Flags: Fragment;"]
[1800,"'DPEP1'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0031528///microvillus membrane+++GO:0005615///extracellular space+++GO:0016363///nuclear matrix+++GO:0031225///anchored component of membrane+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0045177///apical part of cell+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0005694///chromosome+++GO:0016324///apical plasma membrane+++GO:0042995///cell projection+++GO:0016607///nuclear speck+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0008237///metallopeptidase activity+++GO:0008235///metalloexopeptidase activity+++GO:0070573///metallodipeptidase activity+++GO:0034235///GPI anchor binding+++GO:0008270///zinc ion binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0016805///dipeptidase activity+++GO:0016787///hydrolase activity+++GO:0072341///modified amino acid binding+++GO:0008327///methyl-CpG binding+++GO:0008239///dipeptidyl-peptidase activity+++GO:0008233///peptidase activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process","GO:0006346///methylation-dependent chromatin silencing+++GO:0030336///negative regulation of cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0016999///antibiotic metabolic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035690///cellular response to drug+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006691///leukotriene metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0006366///transcription by RNA polymerase II+++GO:0071732///cellular response to nitric oxide+++GO:0072340///cellular lactam catabolic process+++GO:0006749///glutathione metabolic process+++GO:0050667///homocysteine metabolic process+++GO:0071277///cellular response to calcium ion+++GO:0006508///proteolysis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006915///apoptotic process","dipeptidase 1","[DPEP1_HUMAN|Reviewed]RecName: Full=Dipeptidase 1; EC=3.4.13.19; AltName: Full=Dehydropeptidase-I; AltName: Full=Microsomal dipeptidase; AltName: Full=Renal dipeptidase; Short=hRDP; Flags: Precursor;+++[A0A140VJI3_HUMAN|Unreviewed]RecName: Full=Dipeptidase {ECO:0000256|RuleBase:RU341113}; EC=3.4.13.19 {ECO:0000256|RuleBase:RU341113};+++[H3BP43_HUMAN|Unreviewed]RecName: Full=Dipeptidase {ECO:0000256|RuleBase:RU341113}; EC=3.4.13.19 {ECO:0000256|RuleBase:RU341113}; Flags: Fragment;+++[H3BQS5_HUMAN|Unreviewed]RecName: Full=Dipeptidase {ECO:0000256|RuleBase:RU341113}; EC=3.4.13.19 {ECO:0000256|RuleBase:RU341113}; Flags: Fragment;+++[Q6I9V1_HUMAN|Unreviewed]RecName: Full=Dipeptidase {ECO:0000256|RuleBase:RU341113}; EC=3.4.13.19 {ECO:0000256|RuleBase:RU341113};"]
[1825,"'DSC3'",339.38,384.21,291.64,338.41,null,"H00782///Hypotrichosis and recurrent skin vesicles",null,null,"GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0014704///intercalated disc+++GO:0070062///extracellular exosome+++GO:0001533///cornified envelope+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0030057///desmosome+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0045295///gamma-catenin binding+++GO:0046872///metal ion binding+++GO:0086083///cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication+++GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009267///cellular response to starvation+++GO:0031424///keratinization+++GO:0086073///bundle of His cell-Purkinje myocyte adhesion involved in cell communication+++GO:0070268///cornification+++GO:0001701///in utero embryonic development+++GO:0086042///cardiac muscle cell-cardiac muscle cell adhesion+++GO:0050821///protein stabilization+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0098911///regulation of ventricular cardiac muscle cell action potential+++GO:0007155///cell adhesion","desmocollin 3","[DSC3_HUMAN|Reviewed]RecName: Full=Desmocollin-3; AltName: Full=Cadherin family member 3; AltName: Full=Desmocollin-4; AltName: Full=HT-CP; Flags: Precursor;+++[A0A024RC29_HUMAN|Unreviewed]SubName: Full=Desmocollin 3, isoform CRA_b {ECO:0000313|EMBL:EAX01249.1};+++[A9X9K9_HUMAN|Unreviewed]SubName: Full=Desmocollin 2 {ECO:0000313|EMBL:ABM88170.1};+++[A9X9L0_HUMAN|Unreviewed]SubName: Full=Desmocollin 2 {ECO:0000313|EMBL:ABM88171.1};+++[A9X9L1_HUMAN|Unreviewed]SubName: Full=Desmocollin 2 {ECO:0000313|EMBL:ABM88172.1}; Flags: Fragment;+++[J3QRL9_HUMAN|Unreviewed]SubName: Full=Desmocollin-3 {ECO:0000313|Ensembl:ENSP00000464283}; Flags: Fragment;+++[Q9HAX1_HUMAN|Unreviewed]SubName: Full=Desmocollin 3 {ECO:0000313|EMBL:AAG17896.1}; Flags: Fragment;"]
[1840,"'DTX1'",29,33,46,36,"04330///Notch signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016604///nuclear body","GO:0031625///ubiquitin protein ligase binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0017124///SH3 domain binding+++GO:0005112///Notch binding+++GO:0003713///transcription coactivator activity","GO:0045665///negative regulation of neuron differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0007166///cell surface receptor signaling pathway+++GO:0006351///transcription, DNA-templated+++GO:0010001///glial cell differentiation+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0016567///protein ubiquitination+++GO:0008593///regulation of Notch signaling pathway+++GO:0045581///negative regulation of T cell differentiation+++GO:0007219///Notch signaling pathway","deltex E3 ubiquitin ligase 1","[DTX1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase DTX1; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q61010}; AltName: Full=Protein deltex-1; Short=Deltex1; Short=hDTX1; AltName: Full=RING-type E3 ubiquitin transferase DTX1 {ECO:0000305};"]
[1870,"'E2F2'",0,1,2,1,"04934///Cushing's syndrome+++04218///Cellular senescence+++05223///Non-small cell lung cancer+++05212///Pancreatic cancer+++05225///Hepatocellular carcinoma+++05206///MicroRNAs in cancer+++05226///Gastric cancer+++05220///Chronic myeloid leukemia+++05163///Human cytomegalovirus infection+++05214///Glioma+++05166///HTLV-I infection+++05219///Bladder cancer+++05215///Prostate cancer+++05161///Hepatitis B+++05200///Pathways in cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05218///Melanoma+++05222///Small cell lung cancer+++04110///Cell cycle+++01522///Endocrine resistance+++05224///Breast cancer",null,"M00692///Cell cycle - G1/S transition",null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0090575///RNA polymerase II transcription factor complex","GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding","GO:1990086///lens fiber cell apoptotic process+++GO:0007049///cell cycle+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:0051726///regulation of cell cycle+++GO:0006355///regulation of transcription, DNA-templated","E2F transcription factor 2","[E2F2_HUMAN|Reviewed]RecName: Full=Transcription factor E2F2; Short=E2F-2;"]
[1896,"'EDA'",85,84,92,87,"04060///Cytokine-cytokine receptor interaction","H00625///Tooth agenesis+++H00651///Ectodermal dysplasia",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005581///collagen trimer+++GO:0005856///cytoskeleton+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell+++GO:0005811///lipid droplet+++GO:0005576///extracellular region+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane","GO:0038177///death receptor agonist activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005123///death receptor binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043588///skin development+++GO:0010628///positive regulation of gene expression+++GO:0006955///immune response+++GO:0010469///regulation of signaling receptor activity+++GO:0019221///cytokine-mediated signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0043473///pigmentation+++GO:0060662///salivary gland cavitation+++GO:0007275///multicellular organism development+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0007160///cell-matrix adhesion+++GO:0030154///cell differentiation+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0010467///gene expression+++GO:0061153///trachea gland development+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0060789///hair follicle placode formation+++GO:0001942///hair follicle development","ectodysplasin A","[EDA_HUMAN|Reviewed]RecName: Full=Ectodysplasin-A; AltName: Full=Ectodermal dysplasia protein; Short=EDA protein; Contains: RecName: Full=Ectodysplasin-A, membrane form; Contains: RecName: Full=Ectodysplasin-A, secreted form;+++[A0A0C4DGX3_HUMAN|Unreviewed]SubName: Full=Ectodysplasin-A {ECO:0000313|Ensembl:ENSP00000481963}; SubName: Full=HCG14664 {ECO:0000313|EMBL:EAX05359.1};+++[A0A0K0KSD3_HUMAN|Unreviewed]SubName: Full=Mutant ectodysplasin A {ECO:0000313|EMBL:AIN43840.1};+++[A0A0U5J797_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 7C {ECO:0000313|EMBL:CTQ86092.1};+++[D6RA95_HUMAN|Unreviewed]SubName: Full=Ectodysplasin-A {ECO:0000313|Ensembl:ENSP00000423037}; Flags: Fragment;"]
[192286,"'HIGD2A'",995,1052,1254,1100.33333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0070469///respiratory chain+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane",null,"GO:0043066///negative regulation of apoptotic process+++GO:0055114///oxidation-reduction process","HIG1 hypoxia inducible domain family member 2A","[HIG2A_HUMAN|Reviewed]RecName: Full=HIG1 domain family member 2A, mitochondrial; AltName: Full=RCF1 homolog B; Short=RCF1b;+++[A0A024R7Q3_HUMAN|Unreviewed]SubName: Full=HIG1 domain family, member 2A, isoform CRA_a {ECO:0000313|EMBL:EAW85082.1};"]
[1949,"'EFNB3'",494,587,600,560.333333333333,"04360///Axon guidance","H00458///Craniosynostosis+++H01992///Craniofrontonasal syndrome",null,null,"GO:0099056///integral component of presynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0005887///integral component of plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098686///hippocampal mossy fiber to CA3 synapse","GO:0046875///ephrin receptor binding+++GO:0004713///protein tyrosine kinase activity+++GO:0001618///virus receptor activity+++GO:0005005///transmembrane-ephrin receptor activity","GO:0007275///multicellular organism development+++GO:0050771///negative regulation of axonogenesis+++GO:0016032///viral process+++GO:0031295///T cell costimulation+++GO:0048013///ephrin receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007411///axon guidance+++GO:0046718///viral entry into host cell+++GO:0099557///trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission+++GO:0007628///adult walking behavior+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0016198///axon choice point recognition","ephrin B3","[EFNB3_HUMAN|Reviewed]RecName: Full=Ephrin-B3; AltName: Full=EPH-related receptor transmembrane ligand ELK-L3; AltName: Full=EPH-related receptor tyrosine kinase ligand 8; Short=LERK-8; Flags: Precursor;"]
[196074,"'METTL15'",106,110,98,104.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0071424///rRNA (cytosine-N4-)-methyltransferase activity+++GO:0005515///protein binding","GO:0070475///rRNA base methylation+++GO:0032259///methylation","methyltransferase like 15","[MET15_HUMAN|Reviewed]RecName: Full=Probable methyltransferase-like protein 15; EC=2.1.1.-; AltName: Full=Methyltransferase 5 domain-containing protein 1;+++[A0A0U1RR64_HUMAN|Unreviewed]SubName: Full=Probable methyltransferase-like protein 15 {ECO:0000313|Ensembl:ENSP00000489363};+++[A0A0U1RR76_HUMAN|Unreviewed]SubName: Full=Probable methyltransferase-like protein 15 {ECO:0000313|Ensembl:ENSP00000489381};+++[A0A0U1RRD2_HUMAN|Unreviewed]SubName: Full=Probable methyltransferase-like protein 15 {ECO:0000313|Ensembl:ENSP00000489468};+++[A0A0U1RRF2_HUMAN|Unreviewed]SubName: Full=Probable methyltransferase-like protein 15 {ECO:0000313|Ensembl:ENSP00000489497};+++[B5MC64_HUMAN|Unreviewed]SubName: Full=Probable methyltransferase-like protein 15 {ECO:0000313|Ensembl:ENSP00000385860};+++[F8WD83_HUMAN|Unreviewed]SubName: Full=Probable methyltransferase-like protein 15 {ECO:0000313|Ensembl:ENSP00000396550};"]
[196500,"'PIANP'",3083,3474,3580,3379,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005912///adherens junction+++GO:0016323///basolateral plasma membrane",null,"GO:0050776///regulation of immune response","PILR alpha associated neural protein","[PIANP_HUMAN|Reviewed]RecName: Full=PILR alpha-associated neural protein; AltName: Full=PILR-associating neural protein; AltName: Full=Paired immunoglobin-like type 2 receptor-associating neural protein; Flags: Precursor;+++[F5GZA6_HUMAN|Unreviewed]SubName: Full=PILR alpha-associated neural protein {ECO:0000313|Ensembl:ENSP00000444605}; Flags: Fragment;+++[F5H0N9_HUMAN|Unreviewed]SubName: Full=PILR alpha-associated neural protein {ECO:0000313|Ensembl:ENSP00000438736}; Flags: Fragment;+++[F5H191_HUMAN|Unreviewed]SubName: Full=PILR alpha-associated neural protein {ECO:0000313|Ensembl:ENSP00000443898}; Flags: Fragment;"]
[197257,"'LDHD'",115,113,100,109.333333333333,"00620///Pyruvate metabolism",null,null,"R00197///(R)-Lactate:ferricytochrome-c 2-oxidoreductase   (R)-Lactate + 2 Ferricytochrome c <=> Pyruvate + 2 Ferrocytochrome c + 2 H+","GO:0001669///acrosomal vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus+++GO:0042995///cell projection+++GO:0043159///acrosomal matrix+++GO:0005929///cilium+++GO:0005759///mitochondrial matrix+++GO:0045252///oxoglutarate dehydrogenase complex+++GO:0043209///myelin sheath+++GO:0005654///nucleoplasm+++GO:0045254///pyruvate dehydrogenase complex+++GO:0031514///motile cilium","GO:0008720///D-lactate dehydrogenase activity+++GO:0005515///protein binding+++GO:0043544///lipoamide binding+++GO:0034604///pyruvate dehydrogenase (NAD+) activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051287///NAD binding+++GO:0003824///catalytic activity+++GO:0004148///dihydrolipoyl dehydrogenase activity+++GO:0009055///electron transfer activity+++GO:0071949///FAD binding+++GO:0004458///D-lactate dehydrogenase (cytochrome) activity+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor","GO:0007568///aging+++GO:1903457///lactate catabolic process+++GO:0051068///dihydrolipoamide metabolic process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0042391///regulation of membrane potential+++GO:0006086///acetyl-CoA biosynthetic process from pyruvate+++GO:0006508///proteolysis+++GO:0009106///lipoate metabolic process+++GO:0055114///oxidation-reduction process+++GO:0061732///mitochondrial acetyl-CoA biosynthetic process from pyruvate+++GO:0007369///gastrulation+++GO:0048240///sperm capacitation+++GO:0106077///histone succinylation+++GO:0045454///cell redox homeostasis+++GO:0022900///electron transport chain+++GO:0006103///2-oxoglutarate metabolic process","lactate dehydrogenase D","[LDHD_HUMAN|Reviewed]RecName: Full=Probable D-lactate dehydrogenase, mitochondrial; Short=DLD; Short=Lactate dehydrogenase D; EC=1.1.2.4; Flags: Precursor;+++[A0A1W2PR83_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyl dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000492159};+++[F2Z2E3_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyl dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000388077};+++[F8WDM5_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyl dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000409590};+++[F8WDY5_HUMAN|Unreviewed]SubName: Full=Dihydrolipoyl dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000402593};+++[H3BM70_HUMAN|Unreviewed]SubName: Full=Probable D-lactate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000454260};"]
[1978,"'EIF4EBP1'",667,724,742,711,"04211///Longevity regulating pathway+++04150///mTOR signaling pathway+++04152///AMPK signaling pathway+++03013///RNA transport+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway+++05165///Human papillomavirus infection+++05163///Human cytomegalovirus infection+++05231///Choline metabolism in cancer+++04151///PI3K-Akt signaling pathway+++05221///Acute myeloid leukemia+++01521///EGFR tyrosine kinase inhibitor resistance+++04218///Cellular senescence",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008190///eukaryotic initiation factor 4E binding+++GO:0005515///protein binding+++GO:0030371///translation repressor activity","GO:0008286///insulin receptor signaling pathway+++GO:0045947///negative regulation of translational initiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0017148///negative regulation of translation+++GO:0031929///TOR signaling+++GO:0006417///regulation of translation+++GO:0002192///IRES-dependent translational initiation of linear mRNA","eukaryotic translation initiation factor 4E binding protein 1","[4EBP1_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 4E-binding protein 1; Short=4E-BP1; Short=eIF4E-binding protein 1; AltName: Full=Phosphorylated heat- and acid-stable protein regulated by insulin 1; Short=PHAS-I;"]
[199704,"'ZNF585A'",116.45,105.85,77.78,100.026666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 585A","[Z585A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 585A;+++[A0A0C4DFY4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 585A {ECO:0000313|Ensembl:ENSP00000375998};+++[K7ELR3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 585A {ECO:0000313|Ensembl:ENSP00000466185};+++[K7EN80_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 585A {ECO:0000313|Ensembl:ENSP00000466825};+++[L8EAQ8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF585A {ECO:0000313|EMBL:CCQ43861.1};"]
[199920,"'FYB2'",1054,700,688,814,"04137///Mitophagy - animal+++04015///Rap1 signaling pathway+++04140///Autophagy - animal","H00978///Thrombocytopenia (THC)",null,null,"GO:0001772///immunological synapse+++GO:0016020///membrane+++GO:0045121///membrane raft+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0007229///integrin-mediated signaling pathway+++GO:0033627///cell adhesion mediated by integrin+++GO:0072659///protein localization to plasma membrane+++GO:0050852///T cell receptor signaling pathway","FYN binding protein 2","[FYB2_HUMAN|Reviewed]RecName: Full=FYN-binding protein 2 {ECO:0000244|HGNC:HGNC:27295}; AltName: Full=Activation-dependent, raft-recruited ADAP-like phosphoprotein {ECO:0000303|PubMed:27335501};"]
[200205,"'IBA57'",75.69,68.51,100.98,81.7266666666667,null,"H01894///Multiple mitochondrial dysfunctions syndrome+++H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0016740///transferase activity+++GO:0003723///RNA binding","GO:0016226///iron-sulfur cluster assembly+++GO:0006783///heme biosynthetic process","IBA57, iron-sulfur cluster assembly","[CAF17_HUMAN|Reviewed]RecName: Full=Putative transferase CAF17, mitochondrial; EC=2.1.-.-; AltName: Full=Iron-sulfur cluster assembly factor homolog; Flags: Precursor;+++[B4E1G9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57476 {ECO:0000313|EMBL:BAG64781.1};"]
[200558,"'APLF'",17,23,12,17.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm","GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0016829///lyase activity+++GO:0140078///class I DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0008408///3'-5' exonuclease activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0000012///single strand break repair+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006302///double-strand break repair+++GO:0051106///positive regulation of DNA ligation+++GO:0045191///regulation of isotype switching","aprataxin and PNKP like factor","[APLF_HUMAN|Reviewed]RecName: Full=Aprataxin and PNK-like factor; EC=4.2.99.18; AltName: Full=Apurinic-apyrimidinic endonuclease APLF; AltName: Full=PNK and APTX-like FHA domain-containing protein; AltName: Full=XRCC1-interacting protein 1;+++[E9PRH6_HUMAN|Unreviewed]SubName: Full=Aprataxin and PNK-like factor {ECO:0000313|Ensembl:ENSP00000432297};+++[F8WET0_HUMAN|Unreviewed]SubName: Full=Aprataxin and PNK-like factor {ECO:0000313|Ensembl:ENSP00000393403};"]
[200734,"'SPRED2'",568,588,529,561.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00523///Noonan syndrome and related disorders+++H01986///Legius syndrome",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030658///transport vesicle membrane+++GO:0031410///cytoplasmic vesicle","GO:0019901///protein kinase binding+++GO:0005173///stem cell factor receptor binding+++GO:0005515///protein binding+++GO:0030291///protein serine/threonine kinase inhibitor activity","GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0090311///regulation of protein deacetylation+++GO:0007275///multicellular organism development+++GO:0000188///inactivation of MAPK activity+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator","sprouty related EVH1 domain containing 2","[SPRE2_HUMAN|Reviewed]RecName: Full=Sprouty-related, EVH1 domain-containing protein 2; Short=Spred-2;+++[B3KPL5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31917 fis, clone NT2RP7004925, highly similar to Sprouty-related, EVH1 domain-containing protein 2 {ECO:0000313|EMBL:BAG51727.1};+++[C9J623_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000406481}; Flags: Fragment;+++[C9JG63_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000390595}; Flags: Fragment;+++[H7C065_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393148}; Flags: Fragment;+++[H7C2T4_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000407627}; Flags: Fragment;+++[H7C3Y6_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000414551}; Flags: Fragment;"]
[201255,"'LRRC45'",198,184,188,190,"04140///Autophagy - animal+++04137///Mitophagy - animal+++05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding",null,"leucine rich repeat containing 45","[LRC45_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 45;+++[J3KTD4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 45 {ECO:0000313|Ensembl:ENSP00000462928}; Flags: Fragment;"]
[201305,"'SPNS3'",27,18,31,25.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0046624///sphingolipid transporter activity","GO:0006869///lipid transport+++GO:0055085///transmembrane transport","sphingolipid transporter 3 (putative)","[SPNS3_HUMAN|Reviewed]RecName: Full=Protein spinster homolog 3;+++[I3L3W7_HUMAN|Unreviewed]SubName: Full=Protein spinster homolog 3 {ECO:0000313|Ensembl:ENSP00000460781};"]
[202018,"'TAPT1'",232,240,208,226.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0036064///ciliary basal body+++GO:0042995///cell projection","GO:0016520///growth hormone-releasing hormone receptor activity","GO:0030030///cell projection organization+++GO:0009791///post-embryonic development+++GO:0001701///in utero embryonic development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0045724///positive regulation of cilium assembly+++GO:0007275///multicellular organism development+++GO:0035437///maintenance of protein localization in endoplasmic reticulum+++GO:0051216///cartilage development+++GO:1903012///positive regulation of bone development+++GO:0014032///neural crest cell development+++GO:0061036///positive regulation of cartilage development+++GO:0001503///ossification+++GO:0048706///embryonic skeletal system development+++GO:0030154///cell differentiation","transmembrane anterior posterior transformation 1","[TAPT1_HUMAN|Reviewed]RecName: Full=Transmembrane anterior posterior transformation protein 1 homolog; AltName: Full=Cytomegalovirus partial fusion receptor;+++[B4DJJ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52307 {ECO:0000313|EMBL:BAG58855.1};+++[D6RBK3_HUMAN|Unreviewed]SubName: Full=Transmembrane anterior posterior transformation protein 1 homolog {ECO:0000313|Ensembl:ENSP00000422652};+++[H0Y916_HUMAN|Unreviewed]SubName: Full=Transmembrane anterior posterior transformation protein 1 homolog {ECO:0000313|Ensembl:ENSP00000422752}; Flags: Fragment;+++[H0Y985_HUMAN|Unreviewed]SubName: Full=Transmembrane anterior posterior transformation protein 1 homolog {ECO:0000313|Ensembl:ENSP00000423359}; Flags: Fragment;"]
[202243,"'CCDC125'",105,161,140,135.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0003674///molecular_function","GO:2000145///regulation of cell motility+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:2000146///negative regulation of cell motility+++GO:0090630///activation of GTPase activity","coiled-coil domain containing 125","[CC125_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 125; AltName: Full=Protein kenae;+++[B4DSR1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58730 {ECO:0000313|EMBL:BAG61723.1};+++[F8W912_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 125 {ECO:0000313|Ensembl:ENSP00000372865};+++[Q2HJ12_HUMAN|Unreviewed]SubName: Full=CCDC125 protein {ECO:0000313|EMBL:AAI13750.1};"]
[203197,"'TMEM268'",577,448,461,495.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0008150///biological_process","transmembrane protein 268","[TM268_HUMAN|Reviewed]RecName: Full=Transmembrane protein 268 {ECO:0000312|HGNC:HGNC:24513};"]
[2034,"'EPAS1'",17886,10983,9374,12747.6666666667,"05211///Renal cell carcinoma+++05200///Pathways in cancer","H01510///Malignant paraganglioma+++H00236///Congenital polycythemia",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0008134///transcription factor binding","GO:0002027///regulation of heart rate+++GO:0055072///iron ion homeostasis+++GO:0007005///mitochondrion organization+++GO:0043619///regulation of transcription from RNA polymerase II promoter in response to oxidative stress+++GO:0030154///cell differentiation+++GO:0030324///lung development+++GO:0007275///multicellular organism development+++GO:0043687///post-translational protein modification+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0048511///rhythmic process+++GO:0048469///cell maturation+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0001892///embryonic placenta development+++GO:0071456///cellular response to hypoxia+++GO:0030218///erythrocyte differentiation+++GO:0048625///myoblast fate commitment+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007601///visual perception+++GO:0035914///skeletal muscle cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0001974///blood vessel remodeling+++GO:0006979///response to oxidative stress+++GO:0043129///surfactant homeostasis+++GO:0042415///norepinephrine metabolic process+++GO:0001525///angiogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030097///hemopoiesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001666///response to hypoxia","endothelial PAS domain protein 1","[EPAS1_HUMAN|Reviewed]RecName: Full=Endothelial PAS domain-containing protein 1; Short=EPAS-1; AltName: Full=Basic-helix-loop-helix-PAS protein MOP2; AltName: Full=Class E basic helix-loop-helix protein 73; Short=bHLHe73; AltName: Full=HIF-1-alpha-like factor; Short=HLF; AltName: Full=Hypoxia-inducible factor 2-alpha; Short=HIF-2-alpha; Short=HIF2-alpha; AltName: Full=Member of PAS protein 2; AltName: Full=PAS domain-containing protein 2;+++[B3KW07_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41851 fis, clone NT2RI3003925, highly similar to Endothelial PAS domain-containing protein 1 {ECO:0000313|EMBL:BAG53969.1};+++[C9J9N2_HUMAN|Unreviewed]SubName: Full=Endothelial PAS domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000406137}; Flags: Fragment;+++[Q53SM6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein EPAS1 {ECO:0000313|EMBL:AAY14704.1}; Flags: Fragment;+++[Q53ST6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein EPAS1 {ECO:0000313|EMBL:AAX93237.1}; Flags: Fragment;"]
[204851,"'HIPK1'",1075,944,583,867.333333333333,"04218///Cellular senescence",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0016301///kinase activity","GO:0008284///positive regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0060216///definitive hemopoiesis+++GO:0010842///retina layer formation+++GO:0030182///neuron differentiation+++GO:0045766///positive regulation of angiogenesis+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0034333///adherens junction assembly+++GO:0072577///endothelial cell apoptotic process+++GO:0016310///phosphorylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0009952///anterior/posterior pattern specification+++GO:0060235///lens induction in camera-type eye+++GO:0001654///eye development+++GO:0061072///iris morphogenesis+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway","homeodomain interacting protein kinase 1","[HIPK1_HUMAN|Reviewed]RecName: Full=Homeodomain-interacting protein kinase 1; EC=2.7.11.1; AltName: Full=Nuclear body-associated kinase 2;+++[A0A024R0H9_HUMAN|Unreviewed]SubName: Full=Homeodomain interacting protein kinase 1, isoform CRA_f {ECO:0000313|EMBL:EAW56593.1};+++[B4DZ33_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57817, highly similar to Homeodomain-interacting protein kinase 1 {ECO:0000313|EMBL:BAG63945.1};+++[D6RC95_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 1 {ECO:0000313|Ensembl:ENSP00000422322}; Flags: Fragment;+++[D6RF28_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 1 {ECO:0000313|Ensembl:ENSP00000426695}; Flags: Fragment;+++[H3BLW0_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 1 {ECO:0000313|Ensembl:ENSP00000355191}; Flags: Fragment;+++[J3KP92_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 1 {ECO:0000313|Ensembl:ENSP00000358574};+++[Q5SQL3_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 1 {ECO:0000313|Ensembl:ENSP00000358568};"]
[2054,"'STX2'",353,360.7,320,344.566666666667,"04721///Synaptic vesicle cycle+++04130///SNARE interactions in vesicular transport","H00783///Febrile seizures",null,null,"GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0008021///synaptic vesicle+++GO:0005615///extracellular space+++GO:0042734///presynaptic membrane+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0048787///presynaptic active zone membrane+++GO:0031201///SNARE complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0046983///protein dimerization activity","GO:0006906///vesicle fusion+++GO:0009887///animal organ morphogenesis+++GO:0030154///cell differentiation+++GO:0006886///intracellular protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051259///protein complex oligomerization+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0007398///ectoderm development+++GO:0007340///acrosome reaction+++GO:0033194///response to hydroperoxide+++GO:0007165///signal transduction+++GO:1903575///cornified envelope assembly+++GO:0006887///exocytosis+++GO:0048278///vesicle docking","syntaxin 2","[STX2_HUMAN|Reviewed]RecName: Full=Syntaxin-2; AltName: Full=Epimorphin;+++[J3KNU7_HUMAN|Unreviewed]SubName: Full=Syntaxin-2 {ECO:0000313|Ensembl:ENSP00000342554}; Flags: Fragment;"]
[2070,"'EYA4'",295,209,189,231,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00294///Dilated cardiomyopathy (DCM)+++H00604///Deafness, autosomal dominant",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0008134///transcription factor binding+++GO:0004725///protein tyrosine phosphatase activity","GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045739///positive regulation of DNA repair+++GO:0007275///multicellular organism development+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0007601///visual perception+++GO:0006325///chromatin organization+++GO:0006281///DNA repair+++GO:0048856///anatomical structure development+++GO:0006470///protein dephosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0048839///inner ear development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007605///sensory perception of sound+++GO:0016576///histone dephosphorylation","EYA transcriptional coactivator and phosphatase 4","[EYA4_HUMAN|Reviewed]RecName: Full=Eyes absent homolog 4; EC=3.1.3.48 {ECO:0000250|UniProtKB:Q99502};+++[A0A0S2Z3Q2_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036}; Flags: Fragment;+++[A0A0S2Z3V9_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036}; Flags: Fragment;+++[B4DIV6_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036};+++[B4DRQ6_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036};+++[E7ESD5_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036};+++[E9PLN6_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036};+++[F2Z2Y1_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036};+++[Q96CJ7_HUMAN|Unreviewed]RecName: Full=Eyes absent homolog {ECO:0000256|RuleBase:RU362036}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU362036}; Flags: Fragment;"]
[2086,"'ERV3-1'",408.89,465.51,439.05,437.816666666667,{"$nulls":5},"GO:0003674///molecular_function","GO:0008150///biological_process","endogenous retrovirus group 3 member 1, envelope","[ENR1_HUMAN|Reviewed]RecName: Full=Endogenous retrovirus group 3 member 1 Env polyprotein; AltName: Full=ERV-3 envelope protein; Short=ERV3 envelope protein; AltName: Full=ERV3-1 envelope protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-R envelope protein; Short=ERV-R envelope protein; AltName: Full=HERV-R_7q21.2 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[2100,"'ESR2'",0,1,1,0.666666666666667,"05200///Pathways in cancer+++05224///Breast cancer+++04915///Estrogen signaling pathway+++04917///Prolactin signaling pathway+++01522///Endocrine resistance",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005576///extracellular region+++GO:0005634///nucleus","GO:0005496///steroid binding+++GO:0003677///DNA binding+++GO:0003707///steroid hormone receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0004887///thyroid hormone receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008289///lipid binding+++GO:0008270///zinc ion binding+++GO:0003713///transcription coactivator activity+++GO:0048019///receptor antagonist activity+++GO:0046872///metal ion binding+++GO:0030284///estrogen receptor activity+++GO:0019899///enzyme binding+++GO:0042802///identical protein binding+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0034056///estrogen response element binding+++GO:0043565///sequence-specific DNA binding","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0071392///cellular response to estradiol stimulus+++GO:1900116///extracellular negative regulation of signal transduction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007267///cell-cell signaling+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0030522///intracellular receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030308///negative regulation of cell growth+++GO:0007165///signal transduction","estrogen receptor 2","[ESR2_HUMAN|Reviewed]RecName: Full=Estrogen receptor beta; Short=ER-beta; AltName: Full=Nuclear receptor subfamily 3 group A member 2;+++[F1D8N3_HUMAN|Unreviewed]SubName: Full=Estrogen nuclear receptor beta variant b {ECO:0000313|EMBL:ADZ17332.1}; SubName: Full=Estrogen receptor 2 (ER beta), isoform CRA_d {ECO:0000313|EMBL:EAW80851.1};+++[G3V5S2_HUMAN|Unreviewed]SubName: Full=Estrogen receptor beta {ECO:0000313|Ensembl:ENSP00000452485};+++[Q0PTK2_HUMAN|Unreviewed]SubName: Full=Estrogen receptor beta 4 {ECO:0000313|EMBL:ABG88022.1};+++[Q7LCB3_HUMAN|Unreviewed]SubName: Full=5p152 {ECO:0000313|EMBL:AAG29940.1}; SubName: Full=Estrogen nuclear receptor beta variant a {ECO:0000313|EMBL:ADZ17331.1}; SubName: Full=Estrogen receptor 2 (ER beta), isoform CRA_a {ECO:0000313|EMBL:EAW80845.1}; SubName: Full=Estrogen receptor 2 isoform A {ECO:0000313|EMBL:AHW56473.1};"]
[2137,"'EXTL3'",1457,1416,1370,1414.33333333333,"01100///Metabolic pathways+++00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",null,"M00059///Glycosaminoglycan biosynthesis, heparan sulfate backbone","R05936///UDP-N-acetyl-D-glucosamine + G00163 <=> UDP + G00164+++R05930///UDP-N-acetyl-D-glucosamine + G00157 <=> UDP + G00162","GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0001888///glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0036498///IRE1-mediated unfolded protein response+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0030307///positive regulation of cell growth+++GO:0006486///protein glycosylation","exostosin like glycosyltransferase 3","[EXTL3_HUMAN|Reviewed]RecName: Full=Exostosin-like 3 {ECO:0000303|PubMed:9479495}; EC=2.4.1.223 {ECO:0000305|PubMed:28132690, ECO:0000305|PubMed:28148688}; AltName: Full=EXT-related protein 1 {ECO:0000303|PubMed:9473480}; AltName: Full=Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; AltName: Full=Hereditary multiple exostoses gene isolog {ECO:0000303|Ref.9}; AltName: Full=Multiple exostosis-like protein 3 {ECO:0000303|Ref.6}; AltName: Full=Putative tumor suppressor protein EXTL3 {ECO:0000303|PubMed:9479495};+++[E5RIV6_HUMAN|Unreviewed]SubName: Full=Exostosin-like 3 {ECO:0000313|Ensembl:ENSP00000430652}; Flags: Fragment;+++[E5RK02_HUMAN|Unreviewed]SubName: Full=Exostosin-like 3 {ECO:0000313|Ensembl:ENSP00000431013}; Flags: Fragment;+++[E7ET85_HUMAN|Unreviewed]SubName: Full=Exostosin-like 3 {ECO:0000313|Ensembl:ENSP00000428691};+++[H0YB01_HUMAN|Unreviewed]SubName: Full=Exostosin-like 3 {ECO:0000313|Ensembl:ENSP00000428352}; Flags: Fragment;+++[H0YBJ7_HUMAN|Unreviewed]SubName: Full=Exostosin-like 3 {ECO:0000313|Ensembl:ENSP00000429627}; Flags: Fragment;"]
[216,"'ALDH1A1'",423,662,472,519,"00830///Retinol metabolism+++01100///Metabolic pathways",null,null,"R02123///retinal:NAD+ oxidoreductase   Retinal + NAD+ + H2O <=> Retinoate + NADH + H++++R08385///retinal:NAD+ oxidoreductase   9-cis-Retinal + NAD+ + H2O <=> 9-cis-Retinoic acid + NADH + H+","GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005497///androgen binding+++GO:0051287///NAD binding+++GO:0018479///benzaldehyde dehydrogenase (NAD+) activity+++GO:0005096///GTPase activator activity+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0001758///retinal dehydrogenase activity+++GO:0000166///nucleotide binding+++GO:0016491///oxidoreductase activity","GO:0043547///positive regulation of GTPase activity+++GO:0042572///retinol metabolic process+++GO:0055114///oxidation-reduction process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0006081///cellular aldehyde metabolic process+++GO:0061624///fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate+++GO:0006069///ethanol oxidation+++GO:0001523///retinoid metabolic process","aldehyde dehydrogenase 1 family member A1","[AL1A1_HUMAN|Reviewed]RecName: Full=Retinal dehydrogenase 1 {ECO:0000305}; Short=RALDH 1 {ECO:0000305}; Short=RalDH1 {ECO:0000305}; EC=1.2.1.- {ECO:0000269|PubMed:19296407, ECO:0000269|PubMed:25450233, ECO:0000269|PubMed:26373694}; EC=1.2.1.36 {ECO:0000250|UniProtKB:P51647}; AltName: Full=ALDH-E1; AltName: Full=ALHDII; AltName: Full=Aldehyde dehydrogenase family 1 member A1 {ECO:0000312|HGNC:HGNC:402}; AltName: Full=Aldehyde dehydrogenase, cytosolic {ECO:0000303|PubMed:2591967};+++[Q5SYQ7_HUMAN|Unreviewed]SubName: Full=Retinal dehydrogenase 1 {ECO:0000313|Ensembl:ENSP00000401361}; Flags: Fragment;+++[Q5SYQ8_HUMAN|Unreviewed]SubName: Full=Retinal dehydrogenase 1 {ECO:0000313|Ensembl:ENSP00000388026}; Flags: Fragment;+++[Q5SYQ9_HUMAN|Unreviewed]SubName: Full=Retinal dehydrogenase 1 {ECO:0000313|Ensembl:ENSP00000366138};+++[V9HVX6_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 9 {ECO:0000313|EMBL:ACF94471.1};+++[V9HW83_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase 1 family, member A1, isoform CRA_a {ECO:0000313|EMBL:EAW62544.1}; SubName: Full=Epididymis luminal protein 12 {ECO:0000313|EMBL:ACJ13643.1}; SubName: Full=Epididymis secretory sperm binding protein Li 53e {ECO:0000313|EMBL:ACI45978.1};"]
[2166,"'FAAH'",422,253,393,356,"04723///Retrograde endocannabinoid signaling",{"$nulls":3},"GO:0005762///mitochondrial large ribosomal subunit+++GO:0005856///cytoskeleton+++GO:0005759///mitochondrial matrix+++GO:0031090///organelle membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0009383///rRNA (cytosine-C5-)-methyltransferase activity+++GO:0103073///anandamide amidohydrolase activity+++GO:0102077///oleamide hydrolase activity+++GO:0047372///acylglycerol lipase activity+++GO:0070181///small ribosomal subunit rRNA binding+++GO:0008168///methyltransferase activity+++GO:0017064///fatty acid amide hydrolase activity+++GO:0004040///amidase activity","GO:0042256///mature ribosome assembly+++GO:0019369///arachidonic acid metabolic process+++GO:0009062///fatty acid catabolic process+++GO:0070131///positive regulation of mitochondrial translation+++GO:0031167///rRNA methylation","fatty acid amide hydrolase","[FAAH1_HUMAN|Reviewed]RecName: Full=Fatty-acid amide hydrolase 1; EC=3.5.1.99; AltName: Full=Anandamide amidohydrolase 1; AltName: Full=Oleamide hydrolase 1;+++[Q9UG55_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434A091 {ECO:0000313|EMBL:CAB62530.1}; Flags: Fragment;"]
[219402,"'MTIF3'",419,414,461,431.333333333333,{"$nulls":4},"GO:0005739///mitochondrion","GO:0008135///translation factor activity, RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043022///ribosome binding+++GO:0005515///protein binding+++GO:0043024///ribosomal small subunit binding","GO:0070124///mitochondrial translational initiation+++GO:0006412///translation+++GO:0032790///ribosome disassembly+++GO:0006413///translational initiation","mitochondrial translational initiation factor 3","[IF3M_HUMAN|Reviewed]RecName: Full=Translation initiation factor IF-3, mitochondrial; Short=IF-3(Mt); Short=IF-3Mt; Short=IF3(mt); Short=IF3mt; Flags: Precursor;+++[A0A024RDQ7_HUMAN|Unreviewed]SubName: Full=Mitochondrial translational initiation factor 3, isoform CRA_a {ECO:0000313|EMBL:EAX08409.1};"]
[219539,"'YPEL4'",18,42,43,34.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0046872///metal ion binding","GO:0035087///siRNA loading onto RISC involved in RNA interference+++GO:0021695///cerebellar cortex development+++GO:0006388///tRNA splicing, via endonucleolytic cleavage and ligation+++GO:0031124///mRNA 3'-end processing+++GO:0030423///targeting of mRNA for destruction involved in RNA interference","yippee like 4","[YPEL4_HUMAN|Reviewed]RecName: Full=Protein yippee-like 4;+++[A0A024R4Y8_HUMAN|Unreviewed]RecName: Full=Protein yippee-like {ECO:0000256|RuleBase:RU110713};+++[E9PNP5_HUMAN|Unreviewed]SubName: Full=Protein yippee-like 4 {ECO:0000313|Ensembl:ENSP00000432826}; Flags: Fragment;+++[E9PRC4_HUMAN|Unreviewed]SubName: Full=Protein yippee-like 4 {ECO:0000313|Ensembl:ENSP00000434238};+++[Q8N6P9_HUMAN|Unreviewed]SubName: Full=YPEL4 protein {ECO:0000313|EMBL:AAH29228.1};"]
[219770,"'GJD4'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005921///gap junction+++GO:0005922///connexin complex+++GO:0016020///membrane",null,"GO:0007154///cell communication+++GO:0014717///regulation of satellite cell activation involved in skeletal muscle regeneration","gap junction protein delta 4","[CXD4_HUMAN|Reviewed]RecName: Full=Gap junction delta-4 protein; AltName: Full=Connexin-40.1; Short=Cx40.1;+++[Q8IV12_HUMAN|Unreviewed]SubName: Full=GJD4 protein {ECO:0000313|EMBL:AAH35898.1}; Flags: Fragment;"]
[220001,"'VWCE'",290,414,361,355,"04974///Protein digestion and absorption+++04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0005509///calcium ion binding+++GO:0003674///molecular_function","GO:0098586///cellular response to virus+++GO:0006914///autophagy+++GO:0006508///proteolysis+++GO:0007586///digestion+++GO:0030163///protein catabolic process+++GO:0044267///cellular protein metabolic process","von Willebrand factor C and EGF domains","[VWCE_HUMAN|Reviewed]RecName: Full=von Willebrand factor C and EGF domain-containing protein; AltName: Full=HBV X protein up-regulated gene 11 protein; AltName: Full=HBxAg up-regulated gene 11 protein; Flags: Precursor;+++[A0A024R511_HUMAN|Unreviewed]SubName: Full=von Willebrand factor C and EGF domains, isoform CRA_a {ECO:0000313|EMBL:EAW73931.1};+++[A0A087WVD8_HUMAN|Unreviewed]SubName: Full=von Willebrand factor C and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000479367};+++[B4DS56_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58937 {ECO:0000313|EMBL:BAG61518.1}; SubName: Full=von Willebrand factor C and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000441565};+++[B4DY31_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51386 {ECO:0000313|EMBL:BAG63593.1}; SubName: Full=von Willebrand factor C and EGF domain-containing protein {ECO:0000313|Ensembl:ENSP00000442570};"]
[2203,"'FBP1'",13,13,22,16,"01110///Biosynthesis of secondary metabolites+++01200///Carbon metabolism+++01130///Biosynthesis of antibiotics+++00680///Methane metabolism+++01120///Microbial metabolism in diverse environments+++04152///AMPK signaling pathway+++04910///Insulin signaling pathway+++01100///Metabolic pathways+++00710///Carbon fixation in photosynthetic organisms+++00030///Pentose phosphate pathway+++00010///Glycolysis / Gluconeogenesis+++00051///Fructose and mannose metabolism","H00114///Fructose-1,6-bisphosphatase deficiency","M00165///Reductive pentose phosphate cycle (Calvin cycle)+++M00003///Gluconeogenesis, oxaloacetate => fructose-6P+++M00344///Formaldehyde assimilation, xylulose monophosphate pathway+++M00167///Reductive pentose phosphate cycle, glyceraldehyde-3P => ribulose-5P","R00762///D-Fructose-1,6-bisphosphate 1-phosphohydrolase   D-Fructose 1,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate+++R04780///beta-D-Fructose 1,6-bisphosphate 1-phosphohydrolase   beta-D-Fructose 1,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate","GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0016791///phosphatase activity+++GO:0048029///monosaccharide binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0046872///metal ion binding+++GO:0016208///AMP binding+++GO:0042132///fructose 1,6-bisphosphate 1-phosphatase activity+++GO:0016787///hydrolase activity","GO:0005986///sucrose biosynthetic process+++GO:0016311///dephosphorylation+++GO:0035690///cellular response to drug+++GO:0006000///fructose metabolic process+++GO:0051289///protein homotetramerization+++GO:0030308///negative regulation of cell growth+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0006111///regulation of gluconeogenesis+++GO:0071286///cellular response to magnesium ion+++GO:0006094///gluconeogenesis+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0045820///negative regulation of glycolytic process+++GO:0008152///metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0046580///negative regulation of Ras protein signal transduction","fructose-bisphosphatase 1","[F16P1_HUMAN|Reviewed]RecName: Full=Fructose-1,6-bisphosphatase 1; Short=FBPase 1; EC=3.1.3.11 {ECO:0000269|PubMed:17350621, ECO:0000269|PubMed:8387495}; AltName: Full=D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; AltName: Full=Liver FBPase;+++[Q2TU34_HUMAN|Unreviewed]SubName: Full=Fructose-1,6-bisphosphatase 1 {ECO:0000313|EMBL:EAW92617.1}; SubName: Full=Growth-inhibiting protein 17 {ECO:0000313|EMBL:AAT11153.1}; SubName: Full=cDNA FLJ75786, highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1), mRNA {ECO:0000313|EMBL:BAF84888.1};+++[Q5VZC3_HUMAN|Unreviewed]SubName: Full=Fructose-1,6-bisphosphatase 1 {ECO:0000313|Ensembl:ENSP00000411619}; Flags: Fragment;"]
[220988,"'HNRNPA3'",1358,1273,1183,1271.33333333333,"03040///Spliceosome","H00058///Amyotrophic lateral sclerosis (ALS)+++H02031///Inclusion body myopathy with Paget disease of bone and frontotemporal dementia",null,null,"GO:0005681///spliceosomal complex+++GO:0043005///neuron projection+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:1990124///messenger ribonucleoprotein complex+++GO:0014069///postsynaptic density+++GO:0035770///ribonucleoprotein granule+++GO:0005737///cytoplasm","GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0051033///RNA transmembrane transporter activity+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0016070///RNA metabolic process+++GO:0051028///mRNA transport+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing","heterogeneous nuclear ribonucleoprotein A3","[ROA3_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein A3; Short=hnRNP A3;+++[B4DDB6_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A3, isoform CRA_a {ECO:0000313|EMBL:EAX11063.1}; SubName: Full=cDNA FLJ52659, highly similar to Heterogeneous nuclear ribonucleoprotein A3 {ECO:0000313|EMBL:BAG56677.1}; SubName: Full=cDNA, FLJ79333, highly similar to Heterogeneous nuclear ribonucleoprotein A3 {ECO:0000313|EMBL:BAH14805.1};+++[H7C1J8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A3 {ECO:0000313|Ensembl:ENSP00000400688}; Flags: Fragment;+++[Q65ZQ3_HUMAN|Unreviewed]SubName: Full=FBRNP {ECO:0000313|EMBL:AAB27595.1};+++[Q66K53_HUMAN|Unreviewed]SubName: Full=HNRPA3 protein {ECO:0000313|EMBL:AAH80591.1}; Flags: Fragment;"]
[221154,"'MICU2'",394,393.61,371,386.203333333333,{"$nulls":4},"GO:0034704///calcium channel complex+++GO:0005743///mitochondrial inner membrane+++GO:1990246///uniplex complex+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046982///protein heterodimerization activity","GO:0036444///calcium import into the mitochondrion+++GO:0051562///negative regulation of mitochondrial calcium ion concentration+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0051560///mitochondrial calcium ion homeostasis","mitochondrial calcium uptake 2","[MICU2_HUMAN|Reviewed]RecName: Full=Calcium uptake protein 2, mitochondrial; AltName: Full=EF-hand domain-containing family member A1; Flags: Precursor;+++[A0A0A0MTD5_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000431792}; Flags: Fragment;+++[A0A0S2Z6B0_HUMAN|Unreviewed]SubName: Full=EF-hand domain family member A1 isoform 2 {ECO:0000313|EMBL:ALQ34349.1};+++[A0A0S2Z6V5_HUMAN|Unreviewed]SubName: Full=EF-hand domain family member A1 isoform 1 {ECO:0000313|EMBL:ALQ34348.1}; SubName: Full=EF-hand domain family, member A1, isoform CRA_b {ECO:0000313|EMBL:EAX08313.1}; Flags: Fragment;"]
[221409,"'SPATS1'",4,4,1,3,{"$nulls":5},"GO:0005515///protein binding",null,"spermatogenesis associated serine rich 1","[SPAS1_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated serine-rich protein 1;+++[D6RF91_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated serine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000424823};+++[H0Y9A9_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated serine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000423654}; Flags: Fragment;+++[H0YL21_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 8 {ECO:0000313|Ensembl:ENSP00000453026};"]
[221662,"'RBM24'",449,682,470,533.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:1990904///ribonucleoprotein complex","GO:0003723///RNA binding+++GO:1990825///sequence-specific mRNA binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003676///nucleic acid binding+++GO:1990715///mRNA CDS binding+++GO:0005515///protein binding+++GO:0097157///pre-mRNA intronic binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding","GO:1902811///positive regulation of skeletal muscle fiber differentiation+++GO:0061157///mRNA destabilization+++GO:0030154///cell differentiation+++GO:0008380///RNA splicing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0003197///endocardial cushion development+++GO:0048255///mRNA stabilization+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010830///regulation of myotube differentiation+++GO:1905870///positive regulation of 3'-UTR-mediated mRNA stabilization+++GO:0006417///regulation of translation+++GO:2000766///negative regulation of cytoplasmic translation+++GO:0043488///regulation of mRNA stability+++GO:0045663///positive regulation of myoblast differentiation+++GO:0010831///positive regulation of myotube differentiation+++GO:0006397///mRNA processing+++GO:2000738///positive regulation of stem cell differentiation","RNA binding motif protein 24","[RBM24_HUMAN|Reviewed]RecName: Full=RNA-binding protein 24 {ECO:0000305}; AltName: Full=RNA-binding motif protein 24 {ECO:0000303|PubMed:20977548}; AltName: Full=RNA-binding region-containing protein 6;+++[A8KAI7_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 24, isoform CRA_a {ECO:0000313|EMBL:EAW55378.1}; SubName: Full=cDNA FLJ76592 {ECO:0000313|EMBL:BAF85741.1}; SubName: Full=cDNA, FLJ79505, highly similar to RNA-binding region-containing protein 1 {ECO:0000313|EMBL:BAF98747.1};+++[B7Z6B4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54967 {ECO:0000313|EMBL:BAH13200.1};+++[B7Z6B7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52748 {ECO:0000313|EMBL:BAH13203.1};+++[H0Y8S7_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 24 {ECO:0000313|Ensembl:ENSP00000421971}; Flags: Fragment;+++[H0YA61_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 24 {ECO:0000313|Ensembl:ENSP00000426222}; Flags: Fragment;"]
[2219,"'FCN1'",0,0.99,1,0.663333333333333,{"$nulls":4},"GO:0031232///extrinsic component of external side of plasma membrane+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005581///collagen trimer+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034774///secretory granule lumen","GO:0046872///metal ion binding+++GO:0030246///carbohydrate binding+++GO:0005515///protein binding+++GO:0097367///carbohydrate derivative binding+++GO:0001664///G protein-coupled receptor binding+++GO:0033691///sialic acid binding+++GO:0008329///signaling pattern recognition receptor activity+++GO:0004252///serine-type endopeptidase activity","GO:0006508///proteolysis+++GO:0045087///innate immune response+++GO:0002752///cell surface pattern recognition receptor signaling pathway+++GO:0001867///complement activation, lectin pathway+++GO:0006956///complement activation+++GO:0002376///immune system process+++GO:0043654///recognition of apoptotic cell+++GO:2000484///positive regulation of interleukin-8 secretion+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0034394///protein localization to cell surface","ficolin 1","[FCN1_HUMAN|Reviewed]RecName: Full=Ficolin-1; AltName: Full=Collagen/fibrinogen domain-containing protein 1; AltName: Full=Ficolin-A; AltName: Full=Ficolin-alpha; AltName: Full=M-ficolin; Flags: Precursor;+++[A0A087WVE2_HUMAN|Unreviewed]SubName: Full=Ficolin-1 {ECO:0000313|Ensembl:ENSP00000479379};+++[Q92531_HUMAN|Unreviewed]SubName: Full=p35-related protein {ECO:0000313|EMBL:BAA09707.1}; Flags: Fragment;"]
[222229,"'LRWD1'",367,423,414,401.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005815///microtubule organizing center+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031933///telomeric heterochromatin+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore+++GO:0005721///pericentric heterochromatin+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005730///nucleolus+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000776///kinetochore+++GO:0005694///chromosome+++GO:0000781///chromosome, telomeric region","GO:0008327///methyl-CpG binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0035064///methylated histone binding","GO:0006325///chromatin organization+++GO:0071169///establishment of protein localization to chromatin+++GO:0006260///DNA replication+++GO:0006270///DNA replication initiation","leucine rich repeats and WD repeat domain containing 1","[LRWD1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat and WD repeat-containing protein 1; AltName: Full=Centromere protein 33; Short=CENP-33; AltName: Full=Origin recognition complex-associated protein; Short=ORC-associated protein; Short=ORCA;+++[A0A140VJD0_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 4 {ECO:0000313|EMBL:AEE60917.1};+++[F8WBP5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000418204};+++[F8WDB4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000420650}; Flags: Fragment;+++[H7C4Q9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000417913}; Flags: Fragment;+++[H7C5N7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000420373}; Flags: Fragment;+++[H7C5S6_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000420729}; Flags: Fragment;"]
[222584,"'FAM83B'",187,195,133,171.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0004630///phospholipase D activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0036313///phosphatidylinositol 3-kinase catalytic subunit binding+++GO:0019901///protein kinase binding","GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008283///cell proliferation","family with sequence similarity 83 member B","[FA83B_HUMAN|Reviewed]RecName: Full=Protein FAM83B {ECO:0000305};"]
[2241,"'FER'",449,402,272,374.333333333333,{"$nulls":4},"GO:0015630///microtubule cytoskeleton+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0005938///cell cortex+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0042995///cell projection","GO:0016740///transferase activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0004713///protein tyrosine kinase activity+++GO:0008157///protein phosphatase 1 binding+++GO:0005524///ATP binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004672///protein kinase activity","GO:0010762///regulation of fibroblast migration+++GO:0043304///regulation of mast cell degranulation+++GO:0008283///cell proliferation+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0006935///chemotaxis+++GO:0038109///Kit signaling pathway+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0036119///response to platelet-derived growth factor+++GO:0030335///positive regulation of cell migration+++GO:0030838///positive regulation of actin filament polymerization+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0032496///response to lipopolysaccharide+++GO:0033007///negative regulation of mast cell activation involved in immune response+++GO:0016310///phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0036006///cellular response to macrophage colony-stimulating factor stimulus+++GO:0031532///actin cytoskeleton reorganization+++GO:0007155///cell adhesion+++GO:0006468///protein phosphorylation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0000278///mitotic cell cycle+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0035426///extracellular matrix-cell signaling+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0007165///signal transduction+++GO:0001932///regulation of protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0034614///cellular response to reactive oxygen species+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0035556///intracellular signal transduction+++GO:0050904///diapedesis+++GO:0010591///regulation of lamellipodium assembly+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0032869///cellular response to insulin stimulus+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0000226///microtubule cytoskeleton organization+++GO:0042127///regulation of cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway","FER tyrosine kinase","[FER_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase Fer; EC=2.7.10.2; AltName: Full=Feline encephalitis virus-related kinase FER; AltName: Full=Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; AltName: Full=Proto-oncogene c-Fer; AltName: Full=Tyrosine kinase 3; AltName: Full=p94-Fer;+++[A0A0D9SEV4_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Fer {ECO:0000313|Ensembl:ENSP00000486048};+++[D6RAF9_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Fer {ECO:0000313|Ensembl:ENSP00000421951};+++[Q05DA5_HUMAN|Unreviewed]SubName: Full=FER protein {ECO:0000313|EMBL:AAH17060.1}; Flags: Fragment;+++[Q6PEJ9_HUMAN|Unreviewed]SubName: Full=FER protein {ECO:0000313|EMBL:AAH58030.1};+++[W0S0X4_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|PIRNR:PIRNR000632}; EC=2.7.10.2 {ECO:0000256|PIRNR:PIRNR000632};+++[W0S1B5_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};+++[W0S4B9_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096};"]
[2256,"'FGF11'",1133,1011,1339,1161,null,"H00606///Early infantile epileptic encephalopathy+++H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0005576///extracellular region","GO:0008083///growth factor activity","GO:0007267///cell-cell signaling+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0007399///nervous system development","fibroblast growth factor 11","[FGF11_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor 11; Short=FGF-11; AltName: Full=Fibroblast growth factor homologous factor 3; Short=FHF-3;+++[B7Z1C3_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442};+++[I3L4N4_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442};+++[Q6LA99_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442}; Flags: Fragment;"]
[22797,"'TFEC'",169,150,125,148,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0034605///cellular response to heat","transcription factor EC","[TFEC_HUMAN|Reviewed]RecName: Full=Transcription factor EC; Short=TFE-C; AltName: Full=Class E basic helix-loop-helix protein 34; Short=bHLHe34; AltName: Full=Transcription factor EC-like; Short=hTFEC-L;+++[B7Z757_HUMAN|Unreviewed]SubName: Full=Transcription factor EC {ECO:0000313|Ensembl:ENSP00000417432}; SubName: Full=cDNA FLJ55256, highly similar to Homo sapiens transcription factor EC (TFEC), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH13493.1};+++[Q75KY0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TFEC {ECO:0000313|EMBL:AAS02009.1}; Flags: Fragment;+++[Q75MG2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TFEC {ECO:0000313|EMBL:AAS07449.1}; Flags: Fragment;"]
[2281,"'FKBP1B'",46,93,91,76.6666666666667,{"$nulls":4},"GO:0034704///calcium channel complex+++GO:0005829///cytosol+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005737///cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0019855///calcium channel inhibitor activity+++GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0005102///signaling receptor binding+++GO:0044325///ion channel binding+++GO:0005515///protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0030551///cyclic nucleotide binding+++GO:0005219///ryanodine-sensitive calcium-release channel activity","GO:0006458///'de novo' protein folding+++GO:0019227///neuronal action potential propagation+++GO:1903779///regulation of cardiac conduction+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0002027///regulation of heart rate+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0061077///chaperone-mediated protein folding+++GO:0051284///positive regulation of sequestering of calcium ion+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0042026///protein refolding+++GO:0034220///ion transmembrane transport+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0051775///response to redox state+++GO:0006939///smooth muscle contraction+++GO:0033197///response to vitamin E+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0009749///response to glucose+++GO:0048680///positive regulation of axon regeneration+++GO:0022417///protein maturation by protein folding+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0042542///response to hydrogen peroxide+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0042098///T cell proliferation+++GO:0010033///response to organic substance+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0030073///insulin secretion+++GO:0010459///negative regulation of heart rate","FK506 binding protein 1B","[FKB1B_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1B; Short=PPIase FKBP1B; EC=5.2.1.8; AltName: Full=12.6 kDa FK506-binding protein; Short=12.6 kDa FKBP; Short=FKBP-12.6; AltName: Full=FK506-binding protein 1B; Short=FKBP-1B; AltName: Full=Immunophilin FKBP12.6; AltName: Full=Rotamase; AltName: Full=h-FKBP-12;+++[F8W6G9_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};+++[G5E9U6_HUMAN|Unreviewed]SubName: Full=FK506 binding protein 1B, 12.6 kDa, isoform CRA_c {ECO:0000313|EMBL:EAX00770.1}; SubName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1B {ECO:0000313|Ensembl:ENSP00000416349};+++[H7C0Y3_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1B {ECO:0000313|Ensembl:ENSP00000397444}; Flags: Fragment;"]
[22847,"'ZNF507'",254,204,130,196,{"$nulls":4},"GO:0035097///histone methyltransferase complex+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0010468///regulation of gene expression+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 507","[ZN507_HUMAN|Reviewed]RecName: Full=Zinc finger protein 507;+++[B9EGE7_HUMAN|Unreviewed]SubName: Full=ZNF507 protein {ECO:0000313|EMBL:AAI36418.1}; SubName: Full=Zinc finger protein 507 {ECO:0000313|Ensembl:ENSP00000441549};+++[L8EAR0_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF507 {ECO:0000313|EMBL:CCQ43468.1};"]
[22859,"'ADGRL1'",2439,2358,2083,2293.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0042734///presynaptic membrane+++GO:0030054///cell junction+++GO:0042995///cell projection+++GO:0014069///postsynaptic density+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0043005///neuron projection+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0030424///axon+++GO:0030426///growth cone","GO:0050839///cell adhesion molecule binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0016524///latrotoxin receptor activity","GO:0090129///positive regulation of synapse maturation+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0051965///positive regulation of synapse assembly+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007186///G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor L1","[AGRL1_HUMAN|Reviewed]RecName: Full=Adhesion G protein-coupled receptor L1 {ECO:0000312|HGNC:HGNC:20973}; AltName: Full=Calcium-independent alpha-latrotoxin receptor 1 {ECO:0000250|UniProtKB:O88917}; Short=CIRL-1 {ECO:0000250|UniProtKB:O88917}; AltName: Full=Latrophilin-1 {ECO:0000312|HGNC:HGNC:20973}; AltName: Full=Lectomedin-2; Flags: Precursor;+++[A0PJG2_HUMAN|Unreviewed]SubName: Full=LPHN1 protein {ECO:0000313|EMBL:AAH28296.1}; Flags: Fragment;+++[K7EK47_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor L1 {ECO:0000313|Ensembl:ENSP00000465453}; Flags: Fragment;+++[K7ERC3_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor L1 {ECO:0000313|Ensembl:ENSP00000468197}; Flags: Fragment;+++[K7ESH3_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor L1 {ECO:0000313|Ensembl:ENSP00000468711}; Flags: Fragment;"]
[22868,"'FASTKD2'",347.56,315.76,365.58,342.966666666667,null,"H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0035770///ribonucleoprotein granule+++GO:0042645///mitochondrial nucleoid+++GO:0045171///intercellular bridge","GO:0019843///rRNA binding+++GO:0003723///RNA binding+++GO:0004672///protein kinase activity","GO:0070131///positive regulation of mitochondrial translation+++GO:0006468///protein phosphorylation+++GO:1902775///mitochondrial large ribosomal subunit assembly+++GO:0045333///cellular respiration+++GO:0042254///ribosome biogenesis","FAST kinase domains 2","[FAKD2_HUMAN|Reviewed]RecName: Full=FAST kinase domain-containing protein 2, mitochondrial; Flags: Precursor;+++[A0A024R419_HUMAN|Unreviewed]SubName: Full=KIAA0971, isoform CRA_b {ECO:0000313|EMBL:EAW70398.1};+++[C9JPI6_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000409927}; Flags: Fragment;"]
[22883,"'CLSTN1'",16835,20352,17923,18370,"04210///Apoptosis+++04625///C-type lectin receptor signaling pathway+++04360///Axon guidance+++04973///Carbohydrate digestion and absorption+++00562///Inositol phosphate metabolism+++04666///Fc gamma R-mediated phagocytosis+++05224///Breast cancer+++04212///Longevity regulating pathway - worm+++04750///Inflammatory mediator regulation of TRP channels+++01522///Endocrine resistance+++04012///ErbB signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05163///Human cytomegalovirus infection+++04611///Platelet activation+++05160///Hepatitis C+++05223///Non-small cell lung cancer+++04068///FoxO signaling pathway+++05220///Chronic myeloid leukemia+++04960///Aldosterone-regulated sodium reabsorption+++04014///Ras signaling pathway+++04152///AMPK signaling pathway+++04380///Osteoclast differentiation+++04810///Regulation of actin cytoskeleton+++04664///Fc epsilon RI signaling pathway+++04722///Neurotrophin signaling pathway+++05162///Measles+++04024///cAMP signaling pathway+++04668///TNF signaling pathway+++05211///Renal cell carcinoma+++05165///Human papillomavirus infection+++05215///Prostate cancer+++04915///Estrogen signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++05203///Viral carcinogenesis+++05221///Acute myeloid leukemia+++05225///Hepatocellular carcinoma+++04931///Insulin resistance+++04620///Toll-like receptor signaling pathway+++04725///Cholinergic synapse+++05166///HTLV-I infection+++04151///PI3K-Akt signaling pathway+++05218///Melanoma+++05231///Choline metabolism in cancer+++04070///Phosphatidylinositol signaling system+++05200///Pathways in cancer+++04150///mTOR signaling pathway+++04071///Sphingolipid signaling pathway+++04914///Progesterone-mediated oocyte maturation+++05210///Colorectal cancer+++05169///Epstein-Barr virus infection+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++05146///Amoebiasis+++05100///Bacterial invasion of epithelial cells+++04072///Phospholipase D signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04015///Rap1 signaling pathway+++04930///Type II diabetes mellitus+++04218///Cellular senescence+++05161///Hepatitis B+++05212///Pancreatic cancer+++05214///Glioma+++04919///Thyroid hormone signaling pathway+++04662///B cell receptor signaling pathway+++05226///Gastric cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++01521///EGFR tyrosine kinase inhibitor resistance+++01524///Platinum drug resistance+++04923///Regulation of lipolysis in adipocytes+++04917///Prolactin signaling pathway+++04670///Leukocyte transendothelial migration+++05418///Fluid shear stress and atherosclerosis+++04370///VEGF signaling pathway+++04140///Autophagy - animal+++04926///Relaxin signaling pathway+++05164///Influenza A+++04062///Chemokine signaling pathway+++04510///Focal adhesion+++04211///Longevity regulating pathway+++05230///Central carbon metabolism in cancer+++04650///Natural killer cell mediated cytotoxicity+++05213///Endometrial cancer+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway+++04213///Longevity regulating pathway - multiple species+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05222///Small cell lung cancer+++04630///Jak-STAT signaling pathway","H01431///Cushing's syndrome+++H00031///Breast cancer+++H00027///Ovarian cancer+++H02153///Megalencephaly-capillary malformation syndrome+++H01912///Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi+++H01985///Desmoplastic small round cell tumor+++H00048///Hepatocellular carcinoma+++H01387///Activated PI3K-delta syndrome (APDS)+++H01102///Pituitary adenomas+++H01222///Cowden syndrome","M00676///PI3K-Akt signaling","R04545///ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate","GO:0045202///synapse+++GO:0099065///integral component of spine apparatus membrane+++GO:0042995///cell projection+++GO:0005794///Golgi apparatus+++GO:0098982///GABA-ergic synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:0030054///cell junction+++GO:0042629///mast cell granule+++GO:0045211///postsynaptic membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005783///endoplasmic reticulum+++GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0014069///postsynaptic density+++GO:0016021///integral component of membrane+++GO:0098845///postsynaptic endosome+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0001540///amyloid-beta binding+++GO:0042988///X11-like protein binding+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0035004///phosphatidylinositol 3-kinase activity+++GO:0016740///transferase activity+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0016301///kinase activity+++GO:0019894///kinesin binding","GO:0060374///mast cell differentiation+++GO:0010818///T cell chemotaxis+++GO:0050852///T cell receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0006935///chemotaxis+++GO:0072672///neutrophil extravasation+++GO:0098969///neurotransmitter receptor transport to postsynaptic membrane+++GO:0090128///regulation of synapse maturation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016477///cell migration+++GO:0035754///B cell chemotaxis+++GO:0051965///positive regulation of synapse assembly+++GO:0007165///signal transduction+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0030154///cell differentiation+++GO:0042113///B cell activation+++GO:0006954///inflammatory response+++GO:0007411///axon guidance+++GO:0050806///positive regulation of synaptic transmission+++GO:0002679///respiratory burst involved in defense response+++GO:0010629///negative regulation of gene expression+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0010628///positive regulation of gene expression+++GO:0030217///T cell differentiation+++GO:0001558///regulation of cell growth+++GO:0043303///mast cell degranulation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0001816///cytokine production+++GO:0016310///phosphorylation+++GO:0042110///T cell activation+++GO:0006468///protein phosphorylation+++GO:0045087///innate immune response+++GO:0001779///natural killer cell differentiation+++GO:0007155///cell adhesion+++GO:0019221///cytokine-mediated signaling pathway+++GO:0002250///adaptive immune response+++GO:0030593///neutrophil chemotaxis+++GO:0030168///platelet activation+++GO:0002376///immune system process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0099003///vesicle-mediated transport in synapse+++GO:0035747///natural killer cell chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0033031///positive regulation of neutrophil apoptotic process+++GO:0030101///natural killer cell activation+++GO:0050853///B cell receptor signaling pathway+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0002551///mast cell chemotaxis","calsyntenin 1","[CSTN1_HUMAN|Reviewed]RecName: Full=Calsyntenin-1; AltName: Full=Alcadein-alpha; Short=Alc-alpha; AltName: Full=Alzheimer-related cadherin-like protein; AltName: Full=Non-classical cadherin XB31alpha; Contains: RecName: Full=Soluble Alc-alpha; Short=SAlc-alpha; Contains: RecName: Full=CTF1-alpha; AltName: Full=C-terminal fragment 1-alpha; Flags: Precursor;+++[A0A024R4H1_HUMAN|Unreviewed]SubName: Full=Phosphoinositide-3-kinase, catalytic, delta polypeptide, isoform CRA_a {ECO:0000313|EMBL:EAW71623.1};+++[A0A2K8FKQ1_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit {ECO:0000256|PIRNR:PIRNR000587}; EC=2.7.1.153 {ECO:0000256|PIRNR:PIRNR000587};+++[A0A2K8FKR1_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit {ECO:0000256|PIRNR:PIRNR000587}; EC=2.7.1.153 {ECO:0000256|PIRNR:PIRNR000587};+++[A0A2K8FKT1_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit {ECO:0000256|PIRNR:PIRNR000587}; EC=2.7.1.153 {ECO:0000256|PIRNR:PIRNR000587};+++[A7E2E0_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit {ECO:0000256|PIRNR:PIRNR000587}; EC=2.7.1.153 {ECO:0000256|PIRNR:PIRNR000587};+++[B4E3Q1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61580, highly similar to Calsyntenin-1 {ECO:0000313|EMBL:BAG65563.1};+++[B7ZM44_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit {ECO:0000256|PIRNR:PIRNR000587}; EC=2.7.1.153 {ECO:0000256|PIRNR:PIRNR000587};+++[F8W9P4_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit {ECO:0000256|PIRNR:PIRNR000587}; EC=2.7.1.153 {ECO:0000256|PIRNR:PIRNR000587};+++[Q5SR50_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit {ECO:0000256|PIRNR:PIRNR000587}; EC=2.7.1.153 {ECO:0000256|PIRNR:PIRNR000587};+++[Q5SR54_HUMAN|Unreviewed]SubName: Full=Calsyntenin-1 {ECO:0000313|Ensembl:ENSP00000401934}; Flags: Fragment;"]
[22909,"'FAN1'",314,329,247,296.666666666667,"03460///Fanconi anemia pathway","H01877///Chromosome 15q13.3 microdeletion syndrome",null,null,"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0045171///intercellular bridge","GO:0140036///ubiquitin-dependent protein binding+++GO:0008409///5'-3' exonuclease activity+++GO:0004528///phosphodiesterase I activity+++GO:0070336///flap-structured DNA binding+++GO:0017108///5'-flap endonuclease activity+++GO:0000287///magnesium ion binding+++GO:0042803///protein homodimerization activity","GO:0033683///nucleotide-excision repair, DNA incision+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0006289///nucleotide-excision repair","FANCD2 and FANCI associated nuclease 1","[FAN1_HUMAN|Reviewed]RecName: Full=Fanconi-associated nuclease 1 {ECO:0000303|PubMed:20603015, ECO:0000303|PubMed:20603016, ECO:0000303|PubMed:20671156}; EC=3.1.21.- {ECO:0000269|PubMed:20603015, ECO:0000269|PubMed:20603016, ECO:0000269|PubMed:20671156}; EC=3.1.4.1 {ECO:0000269|PubMed:20603015, ECO:0000269|PubMed:20603016}; AltName: Full=FANCD2/FANCI-associated nuclease 1 {ECO:0000303|PubMed:20603015, ECO:0000303|PubMed:20603016, ECO:0000303|PubMed:20671156}; Short=hFAN1 {ECO:0000303|PubMed:24981866}; AltName: Full=Myotubularin-related protein 15;+++[D9MXF4_HUMAN|Unreviewed]RecName: Full=Fanconi-associated nuclease {ECO:0000256|RuleBase:RU365033}; EC=3.1.4.1 {ECO:0000256|RuleBase:RU365033};+++[H3BQ24_HUMAN|Unreviewed]RecName: Full=Fanconi-associated nuclease {ECO:0000256|RuleBase:RU365033}; EC=3.1.4.1 {ECO:0000256|RuleBase:RU365033};+++[H3BUK3_HUMAN|Unreviewed]RecName: Full=Fanconi-associated nuclease {ECO:0000256|RuleBase:RU365033}; EC=3.1.4.1 {ECO:0000256|RuleBase:RU365033}; Flags: Fragment;+++[X5D7V8_HUMAN|Unreviewed]SubName: Full=FANCD2/FANCI-associated nuclease 1 isoform B {ECO:0000313|EMBL:AHW56685.1};+++[X5D9F0_HUMAN|Unreviewed]RecName: Full=Fanconi-associated nuclease {ECO:0000256|RuleBase:RU365033}; EC=3.1.4.1 {ECO:0000256|RuleBase:RU365033}; Flags: Fragment;+++[X5DRB9_HUMAN|Unreviewed]RecName: Full=Fanconi-associated nuclease {ECO:0000256|RuleBase:RU365033}; EC=3.1.4.1 {ECO:0000256|RuleBase:RU365033}; Flags: Fragment;"]
[22927,"'HABP4'",576,962,836,791.333333333333,"04110///Cell cycle+++04113///Meiosis - yeast+++04111///Cell cycle - yeast",{"$nulls":3},"GO:0005829///cytosol+++GO:0005730///nucleolus+++GO:0016604///nuclear body+++GO:0010494///cytoplasmic stress granule+++GO:0015030///Cajal body+++GO:0097504///Gemini of coiled bodies+++GO:0030017///sarcomere+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005576///extracellular region+++GO:0016528///sarcoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045948///positive regulation of translational initiation+++GO:0043392///negative regulation of DNA binding+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0002576///platelet degranulation+++GO:0006417///regulation of translation+++GO:0071260///cellular response to mechanical stimulus+++GO:0033120///positive regulation of RNA splicing","hyaluronan binding protein 4","[HABP4_HUMAN|Reviewed]RecName: Full=Intracellular hyaluronan-binding protein 4 {ECO:0000303|PubMed:10887182}; Short=IHABP-4 {ECO:0000303|PubMed:10887182}; Short=IHABP4 {ECO:0000303|PubMed:10887182}; AltName: Full=Hyaluronan-binding protein 4 {ECO:0000312|HGNC:HGNC:17062}; AltName: Full=Ki-1/57 intracellular antigen {ECO:0000303|PubMed:10887182};"]
[2296,"'FOXC1'",492,380,472,448,null,"H00535///Lymphedemas+++H01075///Peters anomaly+++H01159///Anterior segment dysgenesis (ASGD)+++H00620///Axenfeld-Rieger syndrome (ARS)",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005720///nuclear heterochromatin+++GO:0005634///nucleus","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001223///transcription coactivator binding+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003713///transcription coactivator activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0044212///transcription regulatory region DNA binding+++GO:1990841///promoter-specific chromatin binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008301///DNA binding, bending","GO:0010628///positive regulation of gene expression+++GO:0001503///ossification+++GO:0072010///glomerular epithelium development+++GO:0048762///mesenchymal cell differentiation+++GO:0016477///cell migration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0001701///in utero embryonic development+++GO:0070098///chemokine-mediated signaling pathway+++GO:0030203///glycosaminoglycan metabolic process+++GO:0045930///negative regulation of mitotic cell cycle+++GO:0048341///paraxial mesoderm formation+++GO:0048844///artery morphogenesis+++GO:0001974///blood vessel remodeling+++GO:0043388///positive regulation of DNA binding+++GO:0021549///cerebellum development+++GO:0030199///collagen fibril organization+++GO:1904798///positive regulation of core promoter binding+++GO:0008354///germ cell migration+++GO:0001501///skeletal system development+++GO:0008283///cell proliferation+++GO:0045618///positive regulation of keratinocyte differentiation+++GO:0046620///regulation of organ growth+++GO:0036438///maintenance of lens transparency+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0032808///lacrimal gland development+++GO:0016525///negative regulation of angiogenesis+++GO:0014032///neural crest cell development+++GO:1901534///positive regulation of hematopoietic progenitor cell differentiation+++GO:0001541///ovarian follicle development+++GO:0001958///endochondral ossification+++GO:0014031///mesenchymal cell development+++GO:0050880///regulation of blood vessel size+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1990869///cellular response to chemokine+++GO:0001756///somitogenesis+++GO:1902257///negative regulation of apoptotic process involved in outflow tract morphogenesis+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:1901491///negative regulation of lymphangiogenesis+++GO:0035050///embryonic heart tube development+++GO:0003007///heart morphogenesis+++GO:0007507///heart development+++GO:0001657///ureteric bud development+++GO:0001822///kidney development+++GO:0007219///Notch signaling pathway+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0001568///blood vessel development+++GO:0001525///angiogenesis+++GO:1902038///positive regulation of hematopoietic stem cell differentiation+++GO:0009653///anatomical structure morphogenesis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0001654///eye development+++GO:0007420///brain development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0001945///lymph vessel development+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060038///cardiac muscle cell proliferation+++GO:0007275///multicellular organism development+++GO:0043010///camera-type eye development","forkhead box C1","[FOXC1_HUMAN|Reviewed]RecName: Full=Forkhead box protein C1; AltName: Full=Forkhead-related protein FKHL7; AltName: Full=Forkhead-related transcription factor 3; Short=FREAC-3;+++[A3KPE3_HUMAN|Unreviewed]SubName: Full=FOXC1 protein {ECO:0000313|EMBL:AAI34422.1};+++[C6KMR8_HUMAN|Unreviewed]SubName: Full=Forkhead box C1 {ECO:0000313|EMBL:ACS83750.1};+++[W6CJ52_HUMAN|Unreviewed]SubName: Full=Forkhead box C1 protein {ECO:0000313|EMBL:AHI85954.1};"]
[22983,"'MAST1'",166,282,201,216.333333333333,"04380///Osteoclast differentiation+++04668///TNF signaling pathway","H01463///Mycosis fungoides",null,null,"GO:0000785///chromatin+++GO:0000790///nuclear chromatin+++GO:0005856///cytoskeleton+++GO:0035976///transcription factor AP-1 complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005622///intracellular","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003714///transcription corepressor activity+++GO:0005524///ATP binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0000287///magnesium ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0009612///response to mechanical stimulus+++GO:0033687///osteoblast proliferation+++GO:0006468///protein phosphorylation+++GO:0060716///labyrinthine layer blood vessel development+++GO:0051591///response to cAMP+++GO:0051726///regulation of cell cycle+++GO:0032496///response to lipopolysaccharide+++GO:0009314///response to radiation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0046697///decidualization+++GO:0034097///response to cytokine+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization+++GO:0042127///regulation of cell proliferation+++GO:0001570///vasculogenesis+++GO:0045597///positive regulation of cell differentiation+++GO:0032870///cellular response to hormone stimulus+++GO:0030316///osteoclast differentiation+++GO:0001649///osteoblast differentiation+++GO:0060136///embryonic process involved in female pregnancy+++GO:0071277///cellular response to calcium ion+++GO:0010941///regulation of cell death+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035556///intracellular signal transduction+++GO:0001829///trophectodermal cell differentiation+++GO:0042493///response to drug+++GO:0018105///peptidyl-serine phosphorylation","microtubule associated serine/threonine kinase 1","[MAST1_HUMAN|Reviewed]RecName: Full=Microtubule-associated serine/threonine-protein kinase 1; EC=2.7.11.1; AltName: Full=Syntrophin-associated serine/threonine-protein kinase;"]
[23005,"'MAPKBP1'",1028,928,733,896.333333333333,null,"H00537///Nephronophthisis",null,null,"GO:0097431///mitotic spindle pole+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0000922///spindle pole","GO:0016301///kinase activity+++GO:0005515///protein binding","GO:2000483///negative regulation of interleukin-8 secretion+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:1900425///negative regulation of defense response to bacterium+++GO:0016310///phosphorylation","mitogen-activated protein kinase binding protein 1","[MABP1_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase-binding protein 1; AltName: Full=JNK-binding protein 1; Short=JNKBP-1;+++[A0A024R9L5_HUMAN|Unreviewed]SubName: Full=Mitogen activated protein kinase binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW92518.1};+++[D6R9F7_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000422132}; Flags: Fragment;+++[D6RAI2_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000421891};+++[D6RHX7_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase-binding protein 1 {ECO:0000313|Ensembl:ENSP00000427582};+++[L8E7J2_HUMAN|Unreviewed]SubName: Full=Alternative protein MAPKBP1 {ECO:0000313|EMBL:CCQ43099.1};"]
[23020,"'SNRNP200'",4150,4020,3749,3973,"03040///Spliceosome","H00527///Retinitis pigmentosa (RP)","M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0071013///catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0071014///post-mRNA release spliceosomal complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005682///U5 snRNP+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0008026///ATP-dependent helicase activity+++GO:0004386///helicase activity+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding","GO:0001649///osteoblast differentiation+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000388///spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)+++GO:0000354///cis assembly of pre-catalytic spliceosome+++GO:0006397///mRNA processing","small nuclear ribonucleoprotein U5 subunit 200","[U520_HUMAN|Reviewed]RecName: Full=U5 small nuclear ribonucleoprotein 200 kDa helicase; EC=3.6.4.13 {ECO:0000269|PubMed:23045696}; AltName: Full=Activating signal cointegrator 1 complex subunit 3-like 1; AltName: Full=BRR2 homolog; AltName: Full=U5 snRNP-specific 200 kDa protein; Short=U5-200KD;+++[A2RRQ7_HUMAN|Unreviewed]SubName: Full=SNRNP200 protein {ECO:0000313|EMBL:AAI31785.1};+++[A4FU77_HUMAN|Unreviewed]SubName: Full=SNRNP200 protein {ECO:0000313|EMBL:AAI12892.1}; Flags: Fragment;+++[B4E0P5_HUMAN|Unreviewed]SubName: Full=U5 small nuclear ribonucleoprotein 200 kDa helicase {ECO:0000313|Ensembl:ENSP00000387870}; SubName: Full=cDNA FLJ56901, highly similar to U5 small nuclear ribonucleoprotein 200 kDa helicase {ECO:0000313|EMBL:BAG64507.1};+++[Q5ZF01_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 complex subunit 3-like 1 {ECO:0000313|EMBL:CAH59741.1}; Flags: Fragment;+++[Q7L5W4_HUMAN|Unreviewed]SubName: Full=SNRNP200 protein {ECO:0000313|EMBL:AAH01417.4}; Flags: Fragment;"]
[2304,"'FOXE1'",14,31,21,22,null,"H01202///Cataract+++H01159///Anterior segment dysgenesis (ASGD)+++H01040///Bamforth-Lazarus syndrome+++H00801///Familial thoracic aortic aneurysm and dissection (TAAD)+++H00676///Congenital primary aphakia",null,null,"GO:0005681///spliceosomal complex+++GO:0008023///transcription elongation factor complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0004386///helicase activity+++GO:0008094///DNA-dependent ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity","GO:0060465///pharynx development+++GO:0006353///DNA-templated transcription, termination+++GO:0006590///thyroid hormone generation+++GO:0031069///hair follicle morphogenesis+++GO:0006397///mRNA processing+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060021///roof of mouth development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030878///thyroid gland development+++GO:0060022///hard palate development+++GO:0016477///cell migration+++GO:0006369///termination of RNA polymerase II transcription+++GO:0048538///thymus development+++GO:0048562///embryonic organ morphogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:1904888///cranial skeletal system development+++GO:0030154///cell differentiation+++GO:0009653///anatomical structure morphogenesis+++GO:0060023///soft palate development+++GO:0006357///regulation of transcription by RNA polymerase II","forkhead box E1","[FOXE1_HUMAN|Reviewed]RecName: Full=Forkhead box protein E1; AltName: Full=Forkhead box protein E2; AltName: Full=Forkhead-related protein FKHL15; AltName: Full=HFKH4; AltName: Full=HNF-3/fork head-like protein 5; Short=HFKL5; AltName: Full=Thyroid transcription factor 2; Short=TTF-2;"]
[23057,"'NMNAT2'",93,117,94,101.333333333333,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways","H00837///Leber congenital amaurosis (LCR)","M00115///NAD biosynthesis, aspartate => NAD","R03005///ATP:nicotinamide-nucleotide adenylyltransferase   ATP + Nicotinate D-ribonucleotide <=> Diphosphate + Deamino-NAD++++R00137///ATP:nicotinamide-nucleotide adenylyltransferase   ATP + Nicotinamide D-ribonucleotide <=> Diphosphate + NAD+","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0042995///cell projection+++GO:0000139///Golgi membrane+++GO:0030424///axon+++GO:0045202///synapse+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0030659///cytoplasmic vesicle membrane","GO:0016779///nucleotidyltransferase activity+++GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0004515///nicotinate-nucleotide adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000309///nicotinamide-nucleotide adenylyltransferase activity","GO:0009435///NAD biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0009058///biosynthetic process+++GO:0019674///NAD metabolic process+++GO:0034628///'de novo' NAD biosynthetic process from aspartate","nicotinamide nucleotide adenylyltransferase 2","[NMNA2_HUMAN|Reviewed]RecName: Full=Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 {ECO:0000305}; Short=NMN/NaMN adenylyltransferase 2; EC=2.7.7.1 {ECO:0000269|PubMed:16118205, ECO:0000269|PubMed:17402747}; EC=2.7.7.18 {ECO:0000269|PubMed:16118205, ECO:0000269|PubMed:17402747}; AltName: Full=Nicotinamide mononucleotide adenylyltransferase 2; Short=NMN adenylyltransferase 2; AltName: Full=Nicotinate-nucleotide adenylyltransferase 2; Short=NaMN adenylyltransferase 2;"]
[23077,"'MYCBP2'",627,607,380,538,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0030141///secretory granule+++GO:0043231///intracellular membrane-bounded organelle+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0030667///secretory granule membrane+++GO:0009986///cell surface+++GO:0005802///trans-Golgi network+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0043005///neuron projection+++GO:0030424///axon+++GO:0015630///microtubule cytoskeleton","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0004497///monooxygenase activity+++GO:0031418///L-ascorbic acid binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0016829///lyase activity+++GO:0016491///oxidoreductase activity+++GO:0008536///Ran GTPase binding+++GO:0004504///peptidylglycine monooxygenase activity+++GO:0003824///catalytic activity+++GO:0004598///peptidylamidoglycolate lyase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0042803///protein homodimerization activity+++GO:0019901///protein kinase binding+++GO:0016715///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen+++GO:0005507///copper ion binding+++GO:0016740///transferase activity","GO:0019538///protein metabolic process+++GO:0001666///response to hypoxia+++GO:0042177///negative regulation of protein catabolic process+++GO:0009268///response to pH+++GO:0055114///oxidation-reduction process+++GO:0032355///response to estradiol+++GO:0021952///central nervous system projection neuron axonogenesis+++GO:0007595///lactation+++GO:1902667///regulation of axon guidance+++GO:0046688///response to copper ion+++GO:0001519///peptide amidation+++GO:0021785///branchiomotor neuron axon guidance+++GO:0009404///toxin metabolic process+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0060173///limb development+++GO:0006518///peptide metabolic process+++GO:0051384///response to glucocorticoid+++GO:0042476///odontogenesis+++GO:0018032///protein amidation+++GO:0007417///central nervous system development+++GO:0050708///regulation of protein secretion+++GO:0032880///regulation of protein localization+++GO:0060135///maternal process involved in female pregnancy+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0001676///long-chain fatty acid metabolic process+++GO:0008152///metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051260///protein homooligomerization+++GO:0051493///regulation of cytoskeleton organization+++GO:0008045///motor neuron axon guidance+++GO:0016567///protein ubiquitination+++GO:0007507///heart development+++GO:0050905///neuromuscular process+++GO:0022602///ovulation cycle process+++GO:0042493///response to drug","MYC binding protein 2, E3 ubiquitin protein ligase","[MYCB2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MYCBP2 {ECO:0000305}; EC=2.3.2.- {ECO:0000269|PubMed:29643511}; AltName: Full=Myc-binding protein 2 {ECO:0000305}; AltName: Full=Protein associated with Myc {ECO:0000303|PubMed:9689053};+++[A0A087WY34_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MYCBP2 {ECO:0000313|Ensembl:ENSP00000481482}; Flags: Fragment;+++[A0A0C4DGY7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MYCBP2 {ECO:0000313|Ensembl:ENSP00000483488};+++[D6R961_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000423611}; Flags: Fragment;+++[D6RAQ2_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000421823}; Flags: Fragment;+++[D6RCD5_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000423763}; Flags: Fragment;+++[D6RDU2_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000420851}; Flags: Fragment;+++[D6RF09_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000421569}; Flags: Fragment;+++[D6RG20_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000426448}; Flags: Fragment;+++[F8W8D9_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000302544};+++[H0Y9I4_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000424203}; Flags: Fragment;+++[H7BYD9_HUMAN|Unreviewed]SubName: Full=Peptidyl-glycine alpha-amidating monooxygenase {ECO:0000313|Ensembl:ENSP00000369125}; Flags: Fragment;+++[H7C3U4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MYCBP2 {ECO:0000313|Ensembl:ENSP00000413907}; Flags: Fragment;+++[Q7KYY0_HUMAN|Unreviewed]SubName: Full=Peptidylglycine alpha-amidating monooxygenase {ECO:0000313|EMBL:AAB60658.1}; Flags: Fragment;"]
[23094,"'SIPA1L3'",1768,1760,1604,1710.66666666667,"04015///Rap1 signaling pathway","H01202///Cataract",null,null,"GO:0005615///extracellular space+++GO:0001725///stress fiber+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0061689///tricellular tight junction+++GO:0005886///plasma membrane+++GO:0045177///apical part of cell","GO:0005096///GTPase activator activity","GO:0007010///cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0001654///eye development+++GO:0003382///epithelial cell morphogenesis+++GO:0090162///establishment of epithelial cell polarity+++GO:0051056///regulation of small GTPase mediated signal transduction","signal induced proliferation associated 1 like 3","[SI1L3_HUMAN|Reviewed]RecName: Full=Signal-induced proliferation-associated 1-like protein 3; Short=SIPA1-like protein 3; AltName: Full=SPA-1-like protein 3;+++[B2RWP0_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated 1 like 3 {ECO:0000313|EMBL:AAI50621.1};+++[M0QX89_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated 1-like protein 3 {ECO:0000313|Ensembl:ENSP00000468981}; Flags: Fragment;+++[M0R2Q7_HUMAN|Unreviewed]SubName: Full=Signal-induced proliferation-associated 1-like protein 3 {ECO:0000313|Ensembl:ENSP00000472734}; Flags: Fragment;+++[Q8IUV1_HUMAN|Unreviewed]SubName: Full=SIPA1L3 protein {ECO:0000313|EMBL:AAH36863.1}; Flags: Fragment;"]
[23116,"'TOGARAM1'",332,287,219,279.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005929///cilium+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0036064///ciliary basal body","GO:0042803///protein homodimerization activity","GO:0031116///positive regulation of microtubule polymerization+++GO:0035082///axoneme assembly+++GO:0030030///cell projection organization+++GO:1905515///non-motile cilium assembly","TOG array regulator of axonemal microtubules 1","[TGRM1_HUMAN|Reviewed]RecName: Full=TOG array regulator of axonemal microtubules protein 1 {ECO:0000312|HGNC:HGNC:19959}; AltName: Full=Crescerin-1 {ECO:0000305}; AltName: Full=Protein FAM179B;+++[B4DHM7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52098 {ECO:0000313|EMBL:BAG58189.1};+++[G3V3B1_HUMAN|Unreviewed]SubName: Full=TOG array regulator of axonemal microtubules protein 1 {ECO:0000313|Ensembl:ENSP00000451141}; Flags: Fragment;+++[G3XAE9_HUMAN|Unreviewed]SubName: Full=KIAA0423, isoform CRA_a {ECO:0000313|EMBL:EAW65790.1}; SubName: Full=TOG array regulator of axonemal microtubules protein 1 {ECO:0000313|Ensembl:ENSP00000354917};+++[H0YIY7_HUMAN|Unreviewed]SubName: Full=TOG array regulator of axonemal microtubules protein 1 {ECO:0000313|Ensembl:ENSP00000450465}; Flags: Fragment;+++[H0YJ89_HUMAN|Unreviewed]SubName: Full=TOG array regulator of axonemal microtubules protein 1 {ECO:0000313|Ensembl:ENSP00000451013}; Flags: Fragment;+++[L0R5A8_HUMAN|Unreviewed]SubName: Full=Alternative protein FAM179B {ECO:0000313|EMBL:CCO13729.1};+++[Q6P183_HUMAN|Unreviewed]SubName: Full=FAM179B protein {ECO:0000313|EMBL:AAH65234.1}; Flags: Fragment;"]
[23135,"'KDM6B'",1474,1550,1151,1391.66666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0044666///MLL3/4 complex+++GO:0005634///nucleus","GO:0051213///dioxygenase activity+++GO:0032452///histone demethylase activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0008013///beta-catenin binding+++GO:0016491///oxidoreductase activity+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding","GO:0021766///hippocampus development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0060992///response to fungicide+++GO:0014823///response to activity+++GO:0071557///histone H3-K27 demethylation+++GO:0070301///cellular response to hydrogen peroxide+++GO:0016577///histone demethylation+++GO:0006338///chromatin remodeling+++GO:0045165///cell fate commitment+++GO:0055007///cardiac muscle cell differentiation+++GO:0006325///chromatin organization+++GO:0045446///endothelial cell differentiation+++GO:0010468///regulation of gene expression+++GO:0055114///oxidation-reduction process+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0048333///mesodermal cell differentiation+++GO:0006954///inflammatory response","lysine demethylase 6B","[KDM6B_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 6B; EC=1.14.11.- {ECO:0000269|PubMed:17713478, ECO:0000269|PubMed:17825402, ECO:0000269|PubMed:17851529, ECO:0000269|PubMed:18003914}; AltName: Full=JmjC domain-containing protein 3; AltName: Full=Jumonji domain-containing protein 3; AltName: Full=Lysine demethylase 6B;+++[I3L0Z0_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 6B {ECO:0000313|Ensembl:ENSP00000458445}; Flags: Fragment;"]
[23150,"'FRMD4B'",248,282,247,259,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0005923///bicellular tight junction+++GO:0005856///cytoskeleton+++GO:0005912///adherens junction+++GO:0030054///cell junction","GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding","GO:0090162///establishment of epithelial cell polarity","FERM domain containing 4B","[FRM4B_HUMAN|Reviewed]RecName: Full=FERM domain-containing protein 4B; AltName: Full=GRP1-binding protein GRSP1;+++[B3KNA2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14024 fis, clone HEMBA1003646, highly similar to FERM domain-containing protein 4B {ECO:0000313|EMBL:BAG51264.1};+++[C9J6Q2_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000418373}; Flags: Fragment;+++[C9J7M5_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000417765}; Flags: Fragment;+++[C9JA15_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000417550}; Flags: Fragment;+++[C9JAW0_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000418023}; Flags: Fragment;+++[C9JBX2_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000420735}; Flags: Fragment;+++[C9JYK2_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000419869}; Flags: Fragment;+++[E9PGA7_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000418682};+++[H7C550_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000418962}; Flags: Fragment;+++[Q2TB00_HUMAN|Unreviewed]SubName: Full=FRMD4B protein {ECO:0000313|EMBL:AAI10638.1}; Flags: Fragment;+++[Q6PEW6_HUMAN|Unreviewed]SubName: Full=FRMD4B protein {ECO:0000313|EMBL:AAH57836.1}; Flags: Fragment;"]
[23152,"'CIC'",8544,7516,7361,7807,"04013///MAPK signaling pathway - fly","H00773///Autosomal dominant mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032991///protein-containing complex","GO:0003682///chromatin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0007612///learning+++GO:0007613///memory+++GO:0048286///lung alveolus development+++GO:0035176///social behavior+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007420///brain development","capicua transcriptional repressor","[CIC_HUMAN|Reviewed]RecName: Full=Protein capicua homolog;+++[A0A0A0MQR4_HUMAN|Unreviewed]SubName: Full=Protein capicua homolog {ECO:0000313|Ensembl:ENSP00000160740};+++[I3L135_HUMAN|Unreviewed]SubName: Full=Protein capicua homolog {ECO:0000313|Ensembl:ENSP00000458543}; Flags: Fragment;+++[I3L1Q4_HUMAN|Unreviewed]SubName: Full=Protein capicua homolog {ECO:0000313|Ensembl:ENSP00000459011}; Flags: Fragment;+++[I3L2I4_HUMAN|Unreviewed]SubName: Full=Protein capicua homolog {ECO:0000313|Ensembl:ENSP00000459704}; Flags: Fragment;+++[I3L2J0_HUMAN|Unreviewed]SubName: Full=Protein capicua homolog {ECO:0000313|Ensembl:ENSP00000459719};+++[I3L373_HUMAN|Unreviewed]SubName: Full=Protein capicua homolog {ECO:0000313|Ensembl:ENSP00000460230}; Flags: Fragment;"]
[23184,"'MESD'",1455,1320,1499,1424.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005575///cellular_component","GO:0042802///identical protein binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0003674///molecular_function","GO:1904395///positive regulation of skeletal muscle acetylcholine-gated channel clustering+++GO:0016055///Wnt signaling pathway+++GO:0006457///protein folding+++GO:0007498///mesoderm development+++GO:0034394///protein localization to cell surface+++GO:0006909///phagocytosis","mesoderm development LRP chaperone","[MESD_HUMAN|Reviewed]RecName: Full=LRP chaperone MESD {ECO:0000305}; AltName: Full=LDLR chaperone MESD; AltName: Full=Mesoderm development LRP chaperone MESD {ECO:0000312|HGNC:HGNC:13520}; AltName: Full=Mesoderm development candidate 2; AltName: Full=Mesoderm development protein; AltName: Full=Renal carcinoma antigen NY-REN-61; Flags: Precursor;+++[H0YLI4_HUMAN|Unreviewed]SubName: Full=LRP chaperone MESD {ECO:0000313|Ensembl:ENSP00000453220};"]
[23187,"'PHLDB1'",5929,7582,6826,6779,"01100///Metabolic pathways+++04140///Autophagy - animal+++04137///Mitophagy - animal+++00500///Starch and sucrose metabolism","H02090///Trehalase deficiency",null,"R00010///alpha,alpha-trehalose glucohydrolase alpha,alpha-Trehalose + H2O <=> 2 D-Glucose","GO:0045180///basal cortex",null,"GO:0010717///regulation of epithelial to mesenchymal transition+++GO:1904261///positive regulation of basement membrane assembly involved in embryonic body morphogenesis+++GO:0010470///regulation of gastrulation+++GO:0070507///regulation of microtubule cytoskeleton organization","pleckstrin homology like domain family B member 1","[PHLB1_HUMAN|Reviewed]RecName: Full=Pleckstrin homology-like domain family B member 1; AltName: Full=Protein LL5-alpha;+++[A0A024R3F4_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology-like domain, family B, member 1, isoform CRA_c {ECO:0000313|EMBL:EAW67406.1};+++[A0A024R3H6_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology-like domain, family B, member 1, isoform CRA_b {ECO:0000313|EMBL:EAW67403.1};+++[A0A087WTZ7_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology-like domain family B member 1 {ECO:0000313|Ensembl:ENSP00000478254}; Flags: Fragment;+++[A0A087WXY7_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology-like domain family B member 1 {ECO:0000313|Ensembl:ENSP00000481393};+++[A0A087WZL0_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology-like domain family B member 1 {ECO:0000313|Ensembl:ENSP00000482728}; Flags: Fragment;+++[B0YJ65_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology-like domain family B member 1 variant 4 {ECO:0000313|EMBL:ACA06042.1};+++[Q6ZUD6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43795 fis, clone TESTI4000079 {ECO:0000313|EMBL:BAC86289.1};+++[Q8NC75_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90437 fis, clone NT2RP3000838, weakly similar to TRICHOHYALIN {ECO:0000313|EMBL:BAC11292.1};+++[Q96C94_HUMAN|Unreviewed]SubName: Full=PHLDB1 protein {ECO:0000313|EMBL:AAH14510.1};+++[Q96D60_HUMAN|Unreviewed]SubName: Full=PHLDB1 protein {ECO:0000313|EMBL:AAH13031.2}; Flags: Fragment;"]
[23201,"'FAM168A'",1616,1400,1114,1376.66666666667,"04060///Cytokine-cytokine receptor interaction+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane","GO:0005515///protein binding","GO:1905053///positive regulation of base-excision repair","family with sequence similarity 168 member A","[F168A_HUMAN|Reviewed]RecName: Full=Protein FAM168A; AltName: Full=Tongue cancer chemotherapy resistance-associated protein 1;"]
[23220,"'DTX4'",1042,832,804,892.666666666667,"04330///Notch signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008270///zinc ion binding","GO:0032479///regulation of type I interferon production+++GO:0016567///protein ubiquitination+++GO:0007219///Notch signaling pathway","deltex E3 ubiquitin ligase 4","[DTX4_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase DTX4; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q61010}; AltName: Full=Protein deltex-4; Short=Deltex4; AltName: Full=RING finger protein 155; AltName: Full=RING-type E3 ubiquitin transferase DTX4 {ECO:0000305};"]
[23235,"'SIK2'",1684,2041,1382,1702.33333333333,"04922///Glucagon signaling pathway",{"$nulls":3},"GO:0031588///nucleotide-activated protein kinase complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0000287///magnesium ion binding","GO:0016310///phosphorylation+++GO:0032007///negative regulation of TOR signaling+++GO:0046777///protein autophosphorylation+++GO:0042149///cellular response to glucose starvation+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0046626///regulation of insulin receptor signaling pathway","salt inducible kinase 2","[SIK2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase SIK2; EC=2.7.11.1; AltName: Full=Qin-induced kinase; AltName: Full=Salt-inducible kinase 2; Short=SIK-2; AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 2;+++[A0A024R3G7_HUMAN|Unreviewed]SubName: Full=SNF1-like kinase 2, isoform CRA_c {ECO:0000313|EMBL:EAW67149.1};"]
[23256,"'SCFD1'",475,394,490,453,{"$nulls":4},"GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005798///Golgi-associated vesicle+++GO:0005794///Golgi apparatus+++GO:0032580///Golgi cisterna membrane+++GO:0016021///integral component of membrane+++GO:0005801///cis-Golgi network","GO:0047485///protein N-terminus binding+++GO:0044877///protein-containing complex binding+++GO:0019905///syntaxin binding+++GO:0005515///protein binding","GO:0000902///cell morphogenesis+++GO:0001666///response to hypoxia+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0009636///response to toxic substance+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:1901998///toxin transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0051223///regulation of protein transport+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006904///vesicle docking involved in exocytosis","sec1 family domain containing 1","[SCFD1_HUMAN|Reviewed]RecName: Full=Sec1 family domain-containing protein 1; AltName: Full=SLY1 homolog; Short=Sly1p; AltName: Full=Syntaxin-binding protein 1-like 2;+++[B7Z5N7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58612, highly similar to Sec1 family domain-containing protein 1 {ECO:0000313|EMBL:BAH12973.1};+++[B7Z738_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57213, highly similar to Sec1 family domain-containing protein 1 {ECO:0000313|EMBL:BAH13474.1};+++[G3V2M8_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450755}; Flags: Fragment;+++[G3V363_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000451064};+++[G3V3K9_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000451298};+++[G3V4I1_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000451811};+++[G3V551_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452178};+++[G3V5E2_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452308}; Flags: Fragment;+++[G3V5F3_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452323};+++[H0YIZ7_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450546}; Flags: Fragment;+++[H0YJS6_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452046}; Flags: Fragment;+++[H0YJY1_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452448}; Flags: Fragment;+++[J3KNG4_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000309417};"]
[23269,"'MGA'",512,403,264,393,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0071339///MLL1 complex","GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006351///transcription, DNA-templated+++GO:0070317///negative regulation of G0 to G1 transition","MGA, MAX dimerization protein","[MGAP_HUMAN|Reviewed]RecName: Full=MAX gene-associated protein; AltName: Full=MAX dimerization protein 5;+++[A0A087X194_HUMAN|Unreviewed]SubName: Full=MAX gene-associated protein {ECO:0000313|Ensembl:ENSP00000483990};+++[B9EGR5_HUMAN|Unreviewed]SubName: Full=MGA protein {ECO:0000313|EMBL:AAI36660.1};+++[H3BP52_HUMAN|Unreviewed]SubName: Full=MAX gene-associated protein {ECO:0000313|Ensembl:ENSP00000455155}; Flags: Fragment;+++[H3BTF4_HUMAN|Unreviewed]SubName: Full=MAX gene-associated protein {ECO:0000313|Ensembl:ENSP00000457151}; Flags: Fragment;+++[H3BTN2_HUMAN|Unreviewed]SubName: Full=MAX gene-associated protein {ECO:0000313|Ensembl:ENSP00000457250}; Flags: Fragment;+++[H3BU53_HUMAN|Unreviewed]SubName: Full=MAX gene-associated protein {ECO:0000313|Ensembl:ENSP00000457474}; Flags: Fragment;"]
[2330,"'FMO5'",11,1,2,4.66666666666667,"01120///Microbial metabolism in diverse environments+++00982///Drug metabolism - cytochrome P450","H01234///Trimethylaminuria (TMAU)",null,"R08266///tamoxifen,NADPH:oxygen oxidoreductase (N-oxide-forming)   Tamoxifen + Oxygen + NADPH + H+ <=> Tamoxifen N-oxide + NADP+ + H2O","GO:0031090///organelle membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004499///N,N-dimethylaniline monooxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0004497///monooxygenase activity+++GO:0050661///NADP binding+++GO:0050660///flavin adenine dinucleotide binding","GO:0055114///oxidation-reduction process+++GO:0008150///biological_process","flavin containing monooxygenase 5","[FMO5_HUMAN|Reviewed]RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 5; EC=1.14.13.8; AltName: Full=Dimethylaniline oxidase 5; AltName: Full=Hepatic flavin-containing monooxygenase 5; Short=FMO 5;+++[A0A024QYY6_HUMAN|Unreviewed]RecName: Full=Dimethylaniline monooxygenase [N-oxide-forming] {ECO:0000256|PIRNR:PIRNR000332}; EC=1.14.13.8 {ECO:0000256|PIRNR:PIRNR000332};+++[E9PJF3_HUMAN|Unreviewed]RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177}; EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};+++[E9PP51_HUMAN|Unreviewed]SubName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 5 {ECO:0000313|Ensembl:ENSP00000436429}; Flags: Fragment;+++[E9PQ84_HUMAN|Unreviewed]SubName: Full=Dimethylaniline monooxygenase [N-oxide-forming] 5 {ECO:0000313|Ensembl:ENSP00000432569}; Flags: Fragment;+++[Q9HA79_HUMAN|Unreviewed]RecName: Full=Flavin-containing monooxygenase {ECO:0000256|RuleBase:RU361177}; EC=1.-.-.- {ECO:0000256|RuleBase:RU361177};"]
[23316,"'CUX2'",1,0,1,0.666666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane+++GO:0005634///nucleus","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051965///positive regulation of synapse assembly+++GO:0071310///cellular response to organic substance+++GO:0006355///regulation of transcription, DNA-templated+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0050890///cognition+++GO:0048193///Golgi vesicle transport+++GO:0007614///short-term memory+++GO:0010628///positive regulation of gene expression","cut like homeobox 2","[CUX2_HUMAN|Reviewed]RecName: Full=Homeobox protein cut-like 2; AltName: Full=Homeobox protein cux-2;+++[F5GWR6_HUMAN|Unreviewed]SubName: Full=Homeobox protein cut-like 2 {ECO:0000313|Ensembl:ENSP00000380765}; Flags: Fragment;+++[Q9BZV4_HUMAN|Unreviewed]SubName: Full=Transcription factor CUX2 {ECO:0000313|EMBL:AAG59620.1}; Flags: Fragment;+++[Q9BZX3_HUMAN|Unreviewed]SubName: Full=Neuron specific transcription factor {ECO:0000313|EMBL:AAG59617.1}; Flags: Fragment;"]
[23328,"'SASH1'",1028,711,496,745,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding","GO:1900044///regulation of protein K63-linked ubiquitination+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0010595///positive regulation of endothelial cell migration+++GO:1902498///regulation of protein autoubiquitination+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0045766///positive regulation of angiogenesis+++GO:0043507///positive regulation of JUN kinase activity+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0000209///protein polyubiquitination","SAM and SH3 domain containing 1","[SASH1_HUMAN|Reviewed]RecName: Full=SAM and SH3 domain-containing protein 1; AltName: Full=Proline-glutamate repeat-containing protein;+++[A0A087WW74_HUMAN|Unreviewed]SubName: Full=SAM and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000479998};+++[A0A1B0GVF9_HUMAN|Unreviewed]SubName: Full=SAM and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000490499}; Flags: Fragment;+++[A0A1B0GVI0_HUMAN|Unreviewed]SubName: Full=SAM and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000490521}; Flags: Fragment;+++[A0A1B0GWB9_HUMAN|Unreviewed]SubName: Full=SAM and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000490865}; Flags: Fragment;+++[L8EAS6_HUMAN|Unreviewed]SubName: Full=Alternative protein SASH1 {ECO:0000313|EMBL:CCQ43498.1};+++[Q6P4R9_HUMAN|Unreviewed]SubName: Full=SASH1 protein {ECO:0000313|EMBL:AAH63279.1}; Flags: Fragment;"]
[23355,"'VPS8'",508,487,459,484.666666666667,"04138///Autophagy - yeast",{"$nulls":3},"GO:0005769///early endosome+++GO:0005768///endosome+++GO:0033263///CORVET complex","GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0034058///endosomal vesicle fusion+++GO:0015031///protein transport","VPS8, CORVET complex subunit","[VPS8_HUMAN|Reviewed]RecName: Full=Vacuolar protein sorting-associated protein 8 homolog;+++[B3KPR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32099 fis, clone OCBBF2001140, weakly similar to VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS8 {ECO:0000313|EMBL:BAG51778.1}; Flags: Fragment;+++[C9JG07_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000415161}; Flags: Fragment;+++[C9JIA0_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000416150}; Flags: Fragment;+++[C9JJN9_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000287546};+++[C9JKL0_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000394018}; Flags: Fragment;+++[C9JP71_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000389480};+++[C9JPI1_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000409957}; Flags: Fragment;+++[F8WB24_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000397553};+++[H7C058_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000393070}; Flags: Fragment;+++[H7C1G7_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000400267}; Flags: Fragment;+++[H7C322_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000409115}; Flags: Fragment;+++[H7C490_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 8 homolog {ECO:0000313|Ensembl:ENSP00000416101}; Flags: Fragment;"]
[23365,"'ARHGEF12'",2622,2555,1614,2263.66666666667,"04611///Platelet activation+++04360///Axon guidance+++04810///Regulation of actin cytoskeleton+++05200///Pathways in cancer+++04625///C-type lectin receptor signaling pathway+++04270///Vascular smooth muscle contraction+++05205///Proteoglycans in cancer+++05163///Human cytomegalovirus infection+++05152///Tuberculosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007266///Rho protein signal transduction","Rho guanine nucleotide exchange factor 12","[ARHGC_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 12; AltName: Full=Leukemia-associated RhoGEF;+++[A0A2X0SFF5_HUMAN|Unreviewed]SubName: Full=ARHGEF12 {ECO:0000313|EMBL:SPT35723.1}; Flags: Fragment;+++[B4E2K6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60405, highly similar to Rho guanine nucleotide exchange factor 12 {ECO:0000313|EMBL:BAG65168.1}; Flags: Fragment;+++[E9PMR6_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 12 {ECO:0000313|Ensembl:ENSP00000432984};"]
[23396,"'PIP5K1C'",8154,6183,7214,7183.66666666667,"04072///Phospholipase D signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04139///Mitophagy - yeast+++01100///Metabolic pathways+++04011///MAPK signaling pathway - yeast+++00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++05231///Choline metabolism in cancer+++04810///Regulation of actin cytoskeleton+++04144///Endocytosis","H00865///Lethal congenital contractural syndrome (LCCS)","M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R03469///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase   ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate","GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0005912///adherens junction+++GO:0001931///uropod+++GO:0042995///cell projection+++GO:0012505///endomembrane system+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001891///phagocytic cup+++GO:0098793///presynapse+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005829///cytosol","GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016301///kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity+++GO:0005524///ATP binding+++GO:0052811///1-phosphatidylinositol-3-phosphate 4-kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity","GO:0006887///exocytosis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0007155///cell adhesion+++GO:0034333///adherens junction assembly+++GO:0016310///phosphorylation+++GO:0048488///synaptic vesicle endocytosis+++GO:0098609///cell-cell adhesion+++GO:0072583///clathrin-dependent endocytosis+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0006897///endocytosis+++GO:0030593///neutrophil chemotaxis+++GO:0006909///phagocytosis+++GO:0030036///actin cytoskeleton organization+++GO:0016079///synaptic vesicle exocytosis+++GO:0006935///chemotaxis+++GO:0061024///membrane organization","phosphatidylinositol-4-phosphate 5-kinase type 1 gamma","[PI51C_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; Short=PIP5K1-gamma; Short=PtdIns(4)P-5-kinase 1 gamma; EC=2.7.1.68; AltName: Full=Phosphatidylinositol 4-phosphate 5-kinase type I gamma; Short=PIP5KIgamma;"]
[23404,"'EXOSC2'",100.98,120.51,122,114.496666666667,"03018///RNA degradation",null,"M00391///Exosome, eukaryotes+++M00390///Exosome, archaea",null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0000176///nuclear exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0004532///exoribonuclease activity+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008312///7S RNA binding","GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0034475///U4 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0043488///regulation of mRNA stability+++GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0006364///rRNA processing+++GO:0071049///nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription+++GO:0030307///positive regulation of cell growth+++GO:0071034///CUT catabolic process+++GO:0071051///polyadenylation-dependent snoRNA 3'-end processing","exosome component 2","[EXOS2_HUMAN|Reviewed]RecName: Full=Exosome complex component RRP4 {ECO:0000305}; AltName: Full=Exosome component 2; AltName: Full=Ribosomal RNA-processing protein 4;+++[A2VCR1_HUMAN|Unreviewed]SubName: Full=EXOSC2 protein {ECO:0000313|EMBL:AAI28446.1}; Flags: Fragment;+++[A3KFL1_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP4 {ECO:0000313|Ensembl:ENSP00000361425}; Flags: Fragment;+++[A3KFL2_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP4 {ECO:0000313|Ensembl:ENSP00000361427};+++[A3KFL5_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP4 {ECO:0000313|Ensembl:ENSP00000418463}; Flags: Fragment;+++[B3KQW2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33193 fis, clone ADRGL2005838, highly similar to Exosome complex exonuclease RRP4 {ECO:0000313|EMBL:BAG52174.1};"]
[23439,"'ATP1B4'",2,9,6,5.66666666666667,"04976///Bile secretion+++04961///Endocrine and other factor-regulated calcium reabsorption+++04911///Insulin secretion+++04971///Gastric acid secretion+++04022///cGMP-PKG signaling pathway+++04024///cAMP signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04973///Carbohydrate digestion and absorption+++04925///Aldosterone synthesis and secretion+++04964///Proximal tubule bicarbonate reclamation+++04978///Mineral absorption+++04970///Salivary secretion+++04974///Protein digestion and absorption+++04260///Cardiac muscle contraction+++04918///Thyroid hormone synthesis+++04972///Pancreatic secretion+++04960///Aldosterone-regulated sodium reabsorption+++04919///Thyroid hormone signaling pathway","H00150///Danon disease+++H01781///Autophagic vacuolar myopathy",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0005635///nuclear envelope+++GO:0005634///nucleus","GO:0015077///monovalent inorganic cation transmembrane transporter activity+++GO:0005515///protein binding","GO:0015672///monovalent inorganic cation transport+++GO:0006813///potassium ion transport+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0045944///positive regulation of transcription by RNA polymerase II","ATPase Na+/K+ transporting family member beta 4","[AT1B4_HUMAN|Reviewed]RecName: Full=Protein ATP1B4; AltName: Full=X,K-ATPase subunit beta-m; AltName: Full=X/potassium-transporting ATPase subunit beta-m;+++[B7ZKV8_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};+++[B7ZKV9_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};+++[B7ZKW0_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099};"]
[23456,"'ABCB10'",126,107,87,106.666666666667,"02010///ABC transporters",{"$nulls":3},"GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0005739///mitochondrion","GO:0016887///ATPase activity+++GO:0005524///ATP binding+++GO:0005215///transporter activity+++GO:0000166///nucleotide binding+++GO:0042803///protein homodimerization activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances","GO:0055085///transmembrane transport+++GO:0006839///mitochondrial transport","ATP binding cassette subfamily B member 10","[ABCBA_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family B member 10, mitochondrial; AltName: Full=ATP-binding cassette transporter 10; Short=ABC transporter 10 protein; AltName: Full=Mitochondrial ATP-binding cassette 2; Short=M-ABC2; Flags: Precursor;"]
[23471,"'TRAM1'",3186,2868,2809,2954.33333333333,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005791///rough endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005623///cell+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane","GO:0005515///protein binding+++GO:0038023///signaling receptor activity","GO:0016032///viral process+++GO:0006613///cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0015031///protein transport","translocation associated membrane protein 1","[TRAM1_HUMAN|Reviewed]RecName: Full=Translocating chain-associated membrane protein 1;+++[E5RFP8_HUMAN|Unreviewed]SubName: Full=Translocating chain-associated membrane protein 1 {ECO:0000313|Ensembl:ENSP00000428025}; Flags: Fragment;+++[G3XAN4_HUMAN|Unreviewed]SubName: Full=Translocating chain-associated membrane protein 1 {ECO:0000313|Ensembl:ENSP00000428052}; SubName: Full=Translocation associated membrane protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW86966.1};+++[Q6FHL3_HUMAN|Unreviewed]RecName: Full=Translocating chain-associated membrane protein {ECO:0000256|PIRNR:PIRNR005449};+++[Q6FHU7_HUMAN|Unreviewed]SubName: Full=TRAM1 protein {ECO:0000313|EMBL:CAG46455.1}; Flags: Fragment;"]
[23506,"'BICRAL'",355,328,279,320.666666666667,"05202///Transcriptional misregulation in cancer+++04330///Notch signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016514///SWI/SNF complex",null,null,"BRD4 interacting chromatin remodeling complex associated protein like","[BICRL_HUMAN|Reviewed]RecName: Full=BRD4-interacting chromatin-remodeling complex-associated protein-like {ECO:0000305}; AltName: Full=Glioma tumor suppressor candidate region gene 1 protein-like {ECO:0000312|HGNC:HGNC:21111};+++[L8E875_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0240 {ECO:0000313|EMBL:CCQ43505.1};"]
[23518,"'R3HDM1'",1066,1007,883,985.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding",null,"R3H domain containing 1","[R3HD1_HUMAN|Reviewed]RecName: Full=R3H domain-containing protein 1;+++[C9JIX1_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000416082}; Flags: Fragment;+++[C9JIX3_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000404098}; Flags: Fragment;+++[H7BZ47_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387750}; Flags: Fragment;+++[H7C1X4_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000402940}; Flags: Fragment;+++[H7C207_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000403406}; Flags: Fragment;+++[H7C2F9_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405668}; Flags: Fragment;+++[H7C3T7_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000413763}; Flags: Fragment;+++[Q4ZG59_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein R3HDM {ECO:0000313|EMBL:AAX88922.1}; Flags: Fragment;+++[Q53SQ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein R3HDM {ECO:0000313|EMBL:AAY14728.1}; Flags: Fragment;+++[Q9BVG5_HUMAN|Unreviewed]SubName: Full=R3HDM1 protein {ECO:0000313|EMBL:AAH01217.1};"]
[23543,"'RBFOX2'",2147.49,2285.58,2004.54,2145.87,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0003714///transcription corepressor activity","GO:0016070///RNA metabolic process+++GO:0050885///neuromuscular process controlling balance+++GO:0048813///dendrite morphogenesis+++GO:0042127///regulation of cell proliferation+++GO:0021942///radial glia guided migration of Purkinje cell+++GO:0008380///RNA splicing+++GO:0010724///regulation of definitive erythrocyte differentiation+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0007399///nervous system development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0030520///intracellular estrogen receptor signaling pathway","RNA binding fox-1 homolog 2","[RFOX2_HUMAN|Reviewed]RecName: Full=RNA binding protein fox-1 homolog 2; AltName: Full=Fox-1 homolog B; AltName: Full=Hexaribonucleotide-binding protein 2; AltName: Full=RNA-binding motif protein 9; AltName: Full=RNA-binding protein 9; AltName: Full=Repressor of tamoxifen transcriptional activity;+++[A0A0G2JRA5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein fox-1 homolog 2 {ECO:0000313|Ensembl:ENSP00000486570}; Flags: Fragment;+++[A0A0G2JRD1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein fox-1 homolog 2 {ECO:0000313|Ensembl:ENSP00000486646}; Flags: Fragment;+++[A0A0G2JSB3_HUMAN|Unreviewed]SubName: Full=RNA-binding protein fox-1 homolog 2 {ECO:0000313|Ensembl:ENSP00000487500}; Flags: Fragment;+++[B0QYV1_HUMAN|Unreviewed]RecName: Full=RNA binding protein fox-1 homolog {ECO:0000256|PIRNR:PIRNR037932};+++[B0QYY4_HUMAN|Unreviewed]RecName: Full=RNA binding protein fox-1 homolog {ECO:0000256|PIRNR:PIRNR037932};+++[B0QYY6_HUMAN|Unreviewed]SubName: Full=RNA-binding protein fox-1 homolog 2 {ECO:0000313|Ensembl:ENSP00000380472}; Flags: Fragment;+++[B0QYY7_HUMAN|Unreviewed]SubName: Full=RNA-binding protein fox-1 homolog 2 {ECO:0000313|Ensembl:ENSP00000386177}; Flags: Fragment;+++[F8WSN4_HUMAN|Unreviewed]SubName: Full=RBFOX2 protein {ECO:0000313|EMBL:BAK53481.1}; Flags: Fragment;+++[S4R3K7_HUMAN|Unreviewed]SubName: Full=RNA-binding protein fox-1 homolog 2 {ECO:0000313|Ensembl:ENSP00000474464}; Flags: Fragment;+++[S4R469_HUMAN|Unreviewed]SubName: Full=RNA-binding protein fox-1 homolog 2 {ECO:0000313|Ensembl:ENSP00000475142}; Flags: Fragment;"]
[23559,"'WBP1'",1958,2246,2564,2256,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0050699///WW domain binding",null,"WW domain binding protein 1","[WBP1_HUMAN|Reviewed]RecName: Full=WW domain-binding protein 1; Short=WBP-1;+++[A8MX15_HUMAN|Unreviewed]SubName: Full=HCG2039828, isoform CRA_g {ECO:0000313|EMBL:EAW99664.1}; SubName: Full=WW domain-binding protein 1 {ECO:0000313|Ensembl:ENSP00000377542};+++[B8ZZ95_HUMAN|Unreviewed]SubName: Full=WW domain-binding protein 1 {ECO:0000313|Ensembl:ENSP00000386812};+++[C9JLM6_HUMAN|Unreviewed]SubName: Full=WW domain-binding protein 1 {ECO:0000313|Ensembl:ENSP00000408816}; Flags: Fragment;"]
[23589,"'CARHSP1'",262,252,281,265,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0000177///cytoplasmic exosome (RNase complex)+++GO:0043186///P granule+++GO:0000932///P-body","GO:0003723///RNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003730///mRNA 3'-UTR binding+++GO:0003676///nucleic acid binding+++GO:0019902///phosphatase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0035556///intracellular signal transduction+++GO:0043488///regulation of mRNA stability+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","calcium regulated heat stable protein 1","[CHSP1_HUMAN|Reviewed]RecName: Full=Calcium-regulated heat-stable protein 1; AltName: Full=Calcium-regulated heat-stable protein of 24 kDa; Short=CRHSP-24;+++[H3BNU9_HUMAN|Unreviewed]SubName: Full=Calcium-regulated heat-stable protein 1 {ECO:0000313|Ensembl:ENSP00000455016}; Flags: Fragment;+++[H3BPY5_HUMAN|Unreviewed]SubName: Full=Calcium-regulated heat-stable protein 1 {ECO:0000313|Ensembl:ENSP00000455522}; Flags: Fragment;+++[H3BQY0_HUMAN|Unreviewed]SubName: Full=Calcium-regulated heat-stable protein 1 {ECO:0000313|Ensembl:ENSP00000455988}; Flags: Fragment;+++[H3BSW7_HUMAN|Unreviewed]SubName: Full=Calcium-regulated heat-stable protein 1 {ECO:0000313|Ensembl:ENSP00000456909}; Flags: Fragment;+++[H3BTK3_HUMAN|Unreviewed]SubName: Full=Calcium-regulated heat-stable protein 1 {ECO:0000313|Ensembl:ENSP00000457213}; Flags: Fragment;+++[H3BUY4_HUMAN|Unreviewed]SubName: Full=Calcium-regulated heat-stable protein 1 {ECO:0000313|Ensembl:ENSP00000457864}; Flags: Fragment;+++[I3L3X8_HUMAN|Unreviewed]SubName: Full=Calcium-regulated heat-stable protein 1 {ECO:0000313|Ensembl:ENSP00000460812};"]
[23609,"'MKRN2'",558,554,582,564.666666666667,"05214///Glioma+++04550///Signaling pathways regulating pluripotency of stem cells+++04666///Fc gamma R-mediated phagocytosis+++04072///Phospholipase D signaling pathway+++05165///Human papillomavirus infection+++04664///Fc epsilon RI signaling pathway+++04662///B cell receptor signaling pathway+++04722///Neurotrophin signaling pathway+++05163///Human cytomegalovirus infection+++01521///EGFR tyrosine kinase inhibitor resistance+++04912///GnRH signaling pathway+++05210///Colorectal cancer+++04024///cAMP signaling pathway+++05218///Melanoma+++04810///Regulation of actin cytoskeleton+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++04140///Autophagy - animal+++01522///Endocrine resistance+++05160///Hepatitis C+++05226///Gastric cancer+++04917///Prolactin signaling pathway+++05215///Prostate cancer+++04071///Sphingolipid signaling pathway+++04062///Chemokine signaling pathway+++04151///PI3K-Akt signaling pathway+++05034///Alcoholism+++04210///Apoptosis+++05230///Central carbon metabolism in cancer+++04915///Estrogen signaling pathway+++05219///Bladder cancer+++04371///Apelin signaling pathway+++04022///cGMP-PKG signaling pathway+++04926///Relaxin signaling pathway+++04012///ErbB signaling pathway+++04370///VEGF signaling pathway+++04150///mTOR signaling pathway+++05161///Hepatitis B+++04360///Axon guidance+++04919///Thyroid hormone signaling pathway+++05223///Non-small cell lung cancer+++05231///Choline metabolism in cancer+++05213///Endometrial cancer+++04730///Long-term depression+++04630///Jak-STAT signaling pathway+++04270///Vascular smooth muscle contraction+++04720///Long-term potentiation+++05221///Acute myeloid leukemia+++04650///Natural killer cell mediated cytotoxicity+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++04010///MAPK signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05206///MicroRNAs in cancer+++04910///Insulin signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05152///Tuberculosis+++04625///C-type lectin receptor signaling pathway+++04916///Melanogenesis+++04540///Gap junction+++04014///Ras signaling pathway+++04510///Focal adhesion+++05211///Renal cell carcinoma+++05225///Hepatocellular carcinoma+++04726///Serotonergic synapse+++04015///Rap1 signaling pathway+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++04921///Oxytocin signaling pathway+++05164///Influenza A+++05212///Pancreatic cancer+++05224///Breast cancer+++05220///Chronic myeloid leukemia","H02018///Central precocious puberty","M00687///MAPK (ERK1/2) signaling",null,"GO:0005622///intracellular","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding","GO:0016567///protein ubiquitination+++GO:0008150///biological_process","makorin ring finger protein 2","[MKRN2_HUMAN|Reviewed]RecName: Full=Probable E3 ubiquitin-protein ligase makorin-2; EC=2.3.2.27; AltName: Full=RING finger protein 62; AltName: Full=RING-type E3 ubiquitin transferase makorin-2 {ECO:0000305};+++[C9J494_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase makorin-2 {ECO:0000313|Ensembl:ENSP00000397983};"]
[23640,"'HSPBP1'",567,597,754,639.333333333333,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005737///cytoplasm","GO:0000774///adenyl-nucleotide exchange factor activity+++GO:0004857///enzyme inhibitor activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0031398///positive regulation of protein ubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043086///negative regulation of catalytic activity+++GO:0006457///protein folding+++GO:0050790///regulation of catalytic activity","HSPA (Hsp70) binding protein 1","[HPBP1_HUMAN|Reviewed]RecName: Full=Hsp70-binding protein 1 {ECO:0000305}; Short=HspBP1; AltName: Full=Heat shock protein-binding protein 1; AltName: Full=Hsp70-binding protein 2; Short=HspBP2; AltName: Full=Hsp70-interacting protein 1; AltName: Full=Hsp70-interacting protein 2;+++[A0A024R4R7_HUMAN|Unreviewed]SubName: Full=Hsp70-interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAW72358.1};+++[K7EKM6_HUMAN|Unreviewed]SubName: Full=Hsp70-binding protein 1 {ECO:0000313|Ensembl:ENSP00000465690}; Flags: Fragment;+++[K7EL16_HUMAN|Unreviewed]SubName: Full=Hsp70-binding protein 1 {ECO:0000313|Ensembl:ENSP00000465876}; Flags: Fragment;+++[K7EMM7_HUMAN|Unreviewed]SubName: Full=Hsp70-binding protein 1 {ECO:0000313|Ensembl:ENSP00000466569}; Flags: Fragment;+++[K7EN20_HUMAN|Unreviewed]SubName: Full=Hsp70-binding protein 1 {ECO:0000313|Ensembl:ENSP00000466749}; Flags: Fragment;+++[K7EQQ0_HUMAN|Unreviewed]SubName: Full=Hsp70-binding protein 1 {ECO:0000313|Ensembl:ENSP00000467926}; Flags: Fragment;+++[K7ERT9_HUMAN|Unreviewed]SubName: Full=Hsp70-binding protein 1 {ECO:0000313|Ensembl:ENSP00000468403}; Flags: Fragment;"]
[23671,"'TMEFF2'",42,94,124,86.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0045720///negative regulation of integrin biosynthetic process+++GO:0051497///negative regulation of stress fiber assembly+++GO:0030336///negative regulation of cell migration+++GO:0044319///wound healing, spreading of cells","transmembrane protein with EGF like and two follistatin like domains 2","[TEFF2_HUMAN|Reviewed]RecName: Full=Tomoregulin-2; Short=TR-2; AltName: Full=Hyperplastic polyposis protein 1; AltName: Full=Transmembrane protein with EGF-like and two follistatin-like domains; Flags: Precursor;+++[L8E8R4_HUMAN|Unreviewed]SubName: Full=Alternative protein TMEFF2 {ECO:0000313|EMBL:CCQ43534.1};"]
[23746,"'AIPL1'",2,1.91,4.73,2.88,"04934///Cushing's syndrome","H00837///Leber congenital amaurosis (LCR)+++H01102///Pituitary adenomas+++H01483///Acromegaly+++H01864///Excessive secretion of growth hormone+++H01431///Cushing's syndrome",null,null,"GO:0001917///photoreceptor inner segment+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0001918///farnesylated protein binding+++GO:0051082///unfolded protein binding","GO:0007603///phototransduction, visible light+++GO:0043066///negative regulation of apoptotic process+++GO:0001895///retina homeostasis+++GO:0050896///response to stimulus+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0018343///protein farnesylation+++GO:0007601///visual perception","aryl hydrocarbon receptor interacting protein like 1","[AIPL1_HUMAN|Reviewed]RecName: Full=Aryl-hydrocarbon-interacting protein-like 1;+++[F1T0B5_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|EMBL:BAJ83989.1, ECO:0000313|Ensembl:ENSP00000460134};+++[F1T0B6_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|EMBL:BAJ83990.1};+++[F1T0C0_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|EMBL:BAJ83994.1};+++[F1T0C4_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor interacting protein-like 1, isoform CRA_e {ECO:0000313|EMBL:EAW90315.1}; SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|EMBL:BAJ83998.1, ECO:0000313|Ensembl:ENSP00000459673};+++[I3L3R9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|Ensembl:ENSP00000460672}; Flags: Fragment;+++[J3KPI5_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|Ensembl:ENSP00000370520};+++[K7EPF4_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|Ensembl:ENSP00000467360}; Flags: Fragment;+++[Q6ZZB5_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor interacting protein-like 1 {ECO:0000313|EMBL:CAG17883.1};+++[Q7Z3H1_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor interacting protein-like 1, isoform CRA_b {ECO:0000313|EMBL:EAW90311.1}; SubName: Full=Aryl-hydrocarbon-interacting protein-like 1 {ECO:0000313|Ensembl:ENSP00000458456};"]
[23788,"'MTCH2'",819,821,846.82,828.94,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion",null,"GO:0043065///positive regulation of apoptotic process+++GO:0070585///protein localization to mitochondrion","mitochondrial carrier 2","[MTCH2_HUMAN|Reviewed]RecName: Full=Mitochondrial carrier homolog 2; AltName: Full=Met-induced mitochondrial protein;+++[B4DHQ0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51849, highly similar to Mitochondrial carrier homolog 2 {ECO:0000313|EMBL:BAG58212.1};+++[E9PIE4_HUMAN|Unreviewed]SubName: Full=Mitochondrial carrier homolog 2 {ECO:0000313|Ensembl:ENSP00000432043}; Flags: Fragment;"]
[24145,"'PANX1'",361,329,347,345.666666666667,"04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0032059///bleb+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0005921///gap junction+++GO:0030054///cell junction+++GO:0005886///plasma membrane","GO:0097110///scaffold protein binding+++GO:0003779///actin binding+++GO:0002020///protease binding+++GO:0022840///leak channel activity+++GO:0051015///actin filament binding+++GO:0005243///gap junction channel activity+++GO:0005102///signaling receptor binding+++GO:0005262///calcium channel activity+++GO:0046982///protein heterodimerization activity+++GO:0015267///channel activity+++GO:0055077///gap junction hemi-channel activity+++GO:0044325///ion channel binding","GO:0050715///positive regulation of cytokine secretion+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0070588///calcium ion transmembrane transport+++GO:0034214///protein hexamerization+++GO:0002931///response to ischemia+++GO:0006816///calcium ion transport+++GO:0055085///transmembrane transport+++GO:0050717///positive regulation of interleukin-1 alpha secretion+++GO:0006812///cation transport+++GO:0007267///cell-cell signaling+++GO:0033198///response to ATP+++GO:0006811///ion transport+++GO:0050716///positive regulation of interleukin-1 secretion","pannexin 1","[PANX1_HUMAN|Reviewed]RecName: Full=Pannexin-1;+++[A0A024R397_HUMAN|Unreviewed]RecName: Full=Pannexin {ECO:0000256|RuleBase:RU010713};+++[B6ETL5_HUMAN|Unreviewed]RecName: Full=Pannexin {ECO:0000256|RuleBase:RU010713};"]
[246269,"'AFG1L'",49,30,45,41.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0005524///ATP binding","GO:0035694///mitochondrial protein catabolic process+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0007005///mitochondrion organization","AFG1 like ATPase","[AFG1L_HUMAN|Reviewed]RecName: Full=AFG1-like ATPase {ECO:0000312|HGNC:HGNC:16411}; AltName: Full=Lactation elevated protein 1 {ECO:0000303|PubMed:12079282}; EC=3.6.-.- {ECO:0000305}; AltName: Full=Protein AFG1 homolog;+++[A6ZJA2_HUMAN|Unreviewed]SubName: Full=AFG1-like ATPase {ECO:0000313|Ensembl:ENSP00000392085}; Flags: Fragment;+++[H0Y5F4_HUMAN|Unreviewed]SubName: Full=AFG1-like ATPase {ECO:0000313|Ensembl:ENSP00000398225}; Flags: Fragment;+++[H7C448_HUMAN|Unreviewed]SubName: Full=AFG1-like ATPase {ECO:0000313|Ensembl:ENSP00000415484}; Flags: Fragment;"]
[2517,"'FUCA1'",1335,1487,1516,1446,"00511///Other glycan degradation","H00422///Glycoproteinoses+++H00141///Fucosidosis",null,null,"GO:0043202///lysosomal lumen+++GO:0005576///extracellular region+++GO:0035578///azurophil granule lumen+++GO:0005764///lysosome+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0004560///alpha-L-fucosidase activity+++GO:0016787///hydrolase activity","GO:0006004///fucose metabolic process+++GO:0008152///metabolic process+++GO:0016139///glycoside catabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006027///glycosaminoglycan catabolic process+++GO:0019377///glycolipid catabolic process+++GO:0043312///neutrophil degranulation","alpha-L-fucosidase 1","[FUCO_HUMAN|Reviewed]RecName: Full=Tissue alpha-L-fucosidase; EC=3.2.1.51; AltName: Full=Alpha-L-fucosidase I; AltName: Full=Alpha-L-fucoside fucohydrolase 1; Short=Alpha-L-fucosidase 1; Flags: Precursor;+++[B5MDC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52780, highly similar to Tissue alpha-L-fucosidase {ECO:0000313|EMBL:BAH13453.1};"]
[252995,"'FNDC5'",29,31,36,32,{"$nulls":4},"GO:0005777///peroxisome+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0005179///hormone activity","GO:0090336///positive regulation of brown fat cell differentiation+++GO:0008150///biological_process+++GO:0014850///response to muscle activity+++GO:0010469///regulation of signaling receptor activity","fibronectin type III domain containing 5","[FNDC5_HUMAN|Reviewed]RecName: Full=Fibronectin type III domain-containing protein 5; AltName: Full=Fibronectin type III repeat-containing protein 2; Contains: RecName: Full=Irisin; Flags: Precursor;+++[A0A0A0MRR6_HUMAN|Unreviewed]SubName: Full=Fibronectin type III domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000362570};"]
[253143,"'PRR14L'",484,382,275,380.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity","GO:0006338///chromatin remodeling+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007420///brain development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated","proline rich 14 like","[PR14L_HUMAN|Reviewed]RecName: Full=Protein PRR14L; AltName: Full=Proline rich 14-like protein;+++[C9J9V0_HUMAN|Unreviewed]SubName: Full=Protein PRR14L {ECO:0000313|Ensembl:ENSP00000411129}; Flags: Fragment;+++[H3BLU3_HUMAN|Unreviewed]SubName: Full=Protein PRR14L {ECO:0000313|Ensembl:ENSP00000332169}; Flags: Fragment;+++[H7BZH1_HUMAN|Unreviewed]SubName: Full=Protein PRR14L {ECO:0000313|Ensembl:ENSP00000389527}; Flags: Fragment;+++[H7C1B0_HUMAN|Unreviewed]SubName: Full=Protein PRR14L {ECO:0000313|Ensembl:ENSP00000399381}; Flags: Fragment;"]
[253982,"'ASPHD1'",245,304,397,315.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016491///oxidoreductase activity+++GO:0004597///peptide-aspartate beta-dioxygenase activity+++GO:0051213///dioxygenase activity","GO:0018193///peptidyl-amino acid modification+++GO:0055114///oxidation-reduction process+++GO:0042264///peptidyl-aspartic acid hydroxylation","aspartate beta-hydroxylase domain containing 1","[ASPH1_HUMAN|Reviewed]RecName: Full=Aspartate beta-hydroxylase domain-containing protein 1; EC=1.14.11.-;+++[I3L2A5_HUMAN|Unreviewed]SubName: Full=Aspartate beta-hydroxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459527};+++[I3L2Y2_HUMAN|Unreviewed]SubName: Full=Aspartate beta-hydroxylase domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW79971.1}; SubName: Full=Aspartate beta-hydroxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000460020}; Flags: Fragment;+++[I6L9B0_HUMAN|Unreviewed]SubName: Full=ASPHD1 protein {ECO:0000313|EMBL:AAH34275.2}; Flags: Fragment;"]
[254102,"'EHBP1L1'",827,930,845,867.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005768///endosome","GO:0003674///molecular_function","GO:0008150///biological_process","EH domain binding protein 1 like 1","[EH1L1_HUMAN|Reviewed]RecName: Full=EH domain-binding protein 1-like protein 1;+++[A0A0U1RQH4_HUMAN|Unreviewed]SubName: Full=EH domain-binding protein 1-like protein 1 {ECO:0000313|Ensembl:ENSP00000489002}; Flags: Fragment;+++[E9PIH6_HUMAN|Unreviewed]SubName: Full=EH domain-binding protein 1-like protein 1 {ECO:0000313|Ensembl:ENSP00000431996}; Flags: Fragment;+++[H0YDZ9_HUMAN|Unreviewed]SubName: Full=EH domain-binding protein 1-like protein 1 {ECO:0000313|Ensembl:ENSP00000434693}; Flags: Fragment;+++[L0R4X4_HUMAN|Unreviewed]SubName: Full=Alternative protein EHBP1L1 {ECO:0000313|EMBL:CCO13723.1};"]
[2549,"'GAB1'",921,637,424,660.666666666667,"04012///ErbB signaling pathway+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++01521///EGFR tyrosine kinase inhibitor resistance+++05100///Bacterial invasion of epithelial cells+++05225///Hepatocellular carcinoma+++04072///Phospholipase D signaling pathway+++04722///Neurotrophin signaling pathway+++05226///Gastric cancer+++05205///Proteoglycans in cancer",null,"M00177///Ribosome, eukaryotes",null,"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005925///focal adhesion+++GO:0045202///synapse","GO:0003723///RNA binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0019899///enzyme binding+++GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0017134///fibroblast growth factor binding+++GO:0045296///cadherin binding","GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007411///axon guidance+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0008286///insulin receptor signaling pathway+++GO:0038128///ERBB2 signaling pathway+++GO:0031532///actin cytoskeleton reorganization+++GO:0006413///translational initiation+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0001525///angiogenesis+++GO:0006412///translation+++GO:0008283///cell proliferation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006364///rRNA processing+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0038089///positive regulation of cell migration by vascular endothelial growth factor signaling pathway+++GO:0045766///positive regulation of angiogenesis+++GO:0071353///cellular response to interleukin-4+++GO:0090668///endothelial cell chemotaxis to vascular endothelial growth factor+++GO:0035728///response to hepatocyte growth factor","GRB2 associated binding protein 1","[GAB1_HUMAN|Reviewed]RecName: Full=GRB2-associated-binding protein 1; AltName: Full=GRB2-associated binder 1; AltName: Full=Growth factor receptor bound protein 2-associated protein 1;+++[Q9HA84_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12080 fis, clone HEMBB1002477, highly similar to Human Grb2-associated binder-1 mRNA {ECO:0000313|EMBL:BAB13970.1};"]
[2551,"'GABPA'",253,302,202,252.333333333333,"05010///Alzheimer's disease+++05016///Huntington's disease+++00190///Oxidative phosphorylation+++01100///Metabolic pathways+++04714///Thermogenesis+++05012///Parkinson's disease",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0033613///activating transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003713///transcription coactivator activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0006366///transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization+++GO:0001825///blastocyst formation+++GO:1903351///cellular response to dopamine+++GO:0030154///cell differentiation+++GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development","GA binding protein transcription factor subunit alpha","[GABPA_HUMAN|Reviewed]RecName: Full=GA-binding protein alpha chain; Short=GABP subunit alpha; AltName: Full=Nuclear respiratory factor 2 subunit alpha; AltName: Full=Transcription factor E4TF1-60;+++[A8IE48_HUMAN|Unreviewed]SubName: Full=GA binding protein transcription factor alpha subunit 60kDa {ECO:0000313|EMBL:AFH41795.1}; SubName: Full=GA binding protein transcription factor, alpha subunit 60kDa, isoform CRA_a {ECO:0000313|EMBL:EAX09967.1}; SubName: Full=Nuclear respiratory factor 2 alpha subunit {ECO:0000313|EMBL:ABV90873.1};+++[Q8IYS3_HUMAN|Unreviewed]SubName: Full=GA binding protein transcription factor, alpha subunit 60kDa {ECO:0000313|EMBL:AAH35031.1};"]
[255798,"'SMCO1'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"single-pass membrane protein with coiled-coil domains 1","[SMCO1_HUMAN|Reviewed]RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 1; AltName: Full=Single-pass membrane protein with coiled-coil domains 1;+++[F8WEP5_HUMAN|Unreviewed]SubName: Full=Single-pass membrane and coiled-coil domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000413102};"]
[256051,"'ZNF549'",84,89,73.29,82.0966666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 549","[ZN549_HUMAN|Reviewed]RecName: Full=Zinc finger protein 549;+++[M0QXN3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 549 {ECO:0000313|Ensembl:ENSP00000469280};+++[M0R0L6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 549 {ECO:0000313|Ensembl:ENSP00000471315};"]
[256714,"'MAP7D2'",166,147,117,143.333333333333,{"$nulls":4},"GO:0015630///microtubule cytoskeleton","GO:0005198///structural molecule activity","GO:0000226///microtubule cytoskeleton organization","MAP7 domain containing 2","[MA7D2_HUMAN|Reviewed]RecName: Full=MAP7 domain-containing protein 2;+++[A0A0K1JRJ6_HUMAN|Unreviewed]SubName: Full=MAP7 domain containing 2 brain transcript variant 1 {ECO:0000313|EMBL:ALC74287.1}; SubName: Full=MAP7 domain-containing protein 2 brain specific variant 1 {ECO:0000313|EMBL:AKU19354.1};+++[A0A0K1JS24_HUMAN|Unreviewed]SubName: Full=MAP7 domain containing 2 brain transcript variant 2 {ECO:0000313|EMBL:ALC74288.1}; SubName: Full=MAP7 domain-containing protein 2 brain specific variant 2 {ECO:0000313|EMBL:AKU19355.1};+++[A0A0M3R6J9_HUMAN|Unreviewed]SubName: Full=MAP7 domain containing 2 transcript variant 5 {ECO:0000313|EMBL:ALC74291.1};+++[A0A0M4F6E1_HUMAN|Unreviewed]SubName: Full=MAP7 domain containing 2 brain transcript variant 3 {ECO:0000313|EMBL:ALC74289.1};+++[A0A0M4FLI9_HUMAN|Unreviewed]SubName: Full=MAP7 domain containing 2 brain transcript variant 4 {ECO:0000313|EMBL:ALC74290.1};+++[H9XGZ6_HUMAN|Unreviewed]SubName: Full=MAP7 domain containing 2 protein varaint 1 {ECO:0000313|EMBL:AFG73613.1}; Flags: Fragment;+++[H9XGZ7_HUMAN|Unreviewed]SubName: Full=MAP7 domain containing 2 protein varaint 2 {ECO:0000313|EMBL:AFG73614.1}; Flags: Fragment;"]
[257044,"'CATSPERE'",11,9,16,12,"01100///Metabolic pathways+++04137///Mitophagy - animal+++00230///Purine metabolism+++04140///Autophagy - animal+++00250///Alanine, aspartate and glutamate metabolism","H00594///Distal myopathy","M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R01135///IMP:L-aspartate ligase (GDP-forming) GTP + IMP + L-Aspartate <=> GDP + Orthophosphate + N6-(1,2-Dicarboxyethyl)-AMP","GO:0031514///motile cilium+++GO:0036128///CatSper complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005929///cilium+++GO:0005886///plasma membrane+++GO:0097228///sperm principal piece+++GO:0042995///cell projection","GO:1990380///Lys48-specific deubiquitinase activity+++GO:0005525///GTP binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0042301///phosphate ion binding+++GO:0000287///magnesium ion binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0042803///protein homodimerization activity+++GO:0004019///adenylosuccinate synthase activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity","GO:0006310///DNA recombination+++GO:0006167///AMP biosynthetic process+++GO:0060359///response to ammonium ion+++GO:0046040///IMP metabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0014074///response to purine-containing compound+++GO:0044208///'de novo' AMP biosynthetic process+++GO:0002376///immune system process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0071257///cellular response to electrical stimulus+++GO:0006531///aspartate metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process","catsper channel auxiliary subunit epsilon","[CTSRE_HUMAN|Reviewed]RecName: Full=Cation channel sperm-associated protein subunit epsilon {ECO:0000250|UniProtKB:P0DP43}; Short=CatSper-epsilon {ECO:0000250|UniProtKB:P0DP43}; Short=CatSperepsilon {ECO:0000250|UniProtKB:P0DP43}; Flags: Precursor;+++[B1AQM6_HUMAN|Unreviewed]SubName: Full=Cation channel sperm-associated protein subunit epsilon {ECO:0000313|Ensembl:ENSP00000395796}; Flags: Fragment;"]
[25770,"'C22orf31'",2,11,4,5.66666666666667,{"$nulls":7},"chromosome 22 open reading frame 31","[CV031_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C22orf31;"]
[25790,"'CFAP45'",6,5,5,5.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005929///cilium","GO:0045296///cadherin binding+++GO:0003677///DNA binding","GO:0002576///platelet degranulation+++GO:0030855///epithelial cell differentiation","cilia and flagella associated protein 45","[CFA45_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 45 {ECO:0000312|HGNC:HGNC:17229}; AltName: Full=Coiled-coil domain-containing protein 19 {ECO:0000312|HGNC:HGNC:17229}; AltName: Full=Nasopharyngeal epithelium-specific protein 1 {ECO:0000312|EMBL:AAD55817.1};+++[A0A087WUV1_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 45 {ECO:0000313|Ensembl:ENSP00000478944}; Flags: Fragment;+++[A0A087X182_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 45 {ECO:0000313|Ensembl:ENSP00000483972}; SubName: Full=Coiled-coil domain containing 19, isoform CRA_a {ECO:0000313|EMBL:EAW52765.1};"]
[25797,"'QPCT'",135,175,165,158.333333333333,{"$nulls":4},"GO:0035580///specific granule lumen+++GO:1904724///tertiary granule lumen+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:1904813///ficolin-1-rich granule lumen","GO:0046872///metal ion binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0016603///glutaminyl-peptide cyclotransferase activity","GO:0006464///cellular protein modification process+++GO:0043312///neutrophil degranulation+++GO:0017186///peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase","glutaminyl-peptide cyclotransferase","[QPCT_HUMAN|Reviewed]RecName: Full=Glutaminyl-peptide cyclotransferase; EC=2.3.2.5; AltName: Full=Glutaminyl cyclase; Short=QC; Short=sQC; AltName: Full=Glutaminyl-tRNA cyclotransferase; AltName: Full=Glutamyl cyclase; Short=EC; Flags: Precursor;+++[B5MCZ9_HUMAN|Unreviewed]SubName: Full=Glutaminyl-peptide cyclotransferase {ECO:0000313|Ensembl:ENSP00000385391}; Flags: Fragment;+++[C9JS14_HUMAN|Unreviewed]SubName: Full=Glutaminyl-peptide cyclotransferase {ECO:0000313|Ensembl:ENSP00000389227}; Flags: Fragment;"]
[25825,"'BACE2'",4663.53,4383,4278,4441.51,"05010///Alzheimer's disease",{"$nulls":3},"GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0031045///dense core granule","GO:0016787///hydrolase activity+++GO:0001540///amyloid-beta binding+++GO:0008233///peptidase activity+++GO:0004190///aspartic-type endopeptidase activity","GO:0042593///glucose homeostasis+++GO:0048143///astrocyte activation+++GO:0030163///protein catabolic process+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:0006508///proteolysis+++GO:0050435///amyloid-beta metabolic process+++GO:0016486///peptide hormone processing+++GO:0006509///membrane protein ectodomain proteolysis","beta-secretase 2","[BACE2_HUMAN|Reviewed]RecName: Full=Beta-secretase 2; EC=3.4.23.45; AltName: Full=Aspartic-like protease 56 kDa; AltName: Full=Aspartyl protease 1; Short=ASP1; Short=Asp 1; AltName: Full=Beta-site amyloid precursor protein cleaving enzyme 2; Short=Beta-site APP cleaving enzyme 2; AltName: Full=Down region aspartic protease; Short=DRAP; AltName: Full=Memapsin-1; AltName: Full=Membrane-associated aspartic protease 1; AltName: Full=Theta-secretase; Flags: Precursor;"]
[25830,"'SULT4A1'",90,98,93,93.6666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0008146///sulfotransferase activity+++GO:0004062///aryl sulfotransferase activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0006790///sulfur compound metabolic process+++GO:0008202///steroid metabolic process+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0006629///lipid metabolic process+++GO:0008150///biological_process","sulfotransferase family 4A member 1","[ST4A1_HUMAN|Reviewed]RecName: Full=Sulfotransferase 4A1; Short=ST4A1; EC=2.8.2.-; AltName: Full=Brain sulfotransferase-like protein; Short=hBR-STL; Short=hBR-STL-1; AltName: Full=Nervous system sulfotransferase; Short=NST;+++[A0A024R4X9_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[B7Z2E1_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[F8WE22_HUMAN|Unreviewed]SubName: Full=Sulfotransferase 4A1 {ECO:0000313|Ensembl:ENSP00000414220};"]
[25870,"'SUMF2'",4261,4764,5082,4702.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005788///endoplasmic reticulum lumen+++GO:0005783///endoplasmic reticulum","GO:0046872///metal ion binding","GO:0006687///glycosphingolipid metabolic process+++GO:0043687///post-translational protein modification","sulfatase modifying factor 2","[SUMF2_HUMAN|Reviewed]RecName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000305}; AltName: Full=Paralog of formylglycine-generating enzyme {ECO:0000303|PubMed:15687489, ECO:0000303|PubMed:15708861, ECO:0000303|PubMed:18266766}; Short=pFGE {ECO:0000303|PubMed:15687489, ECO:0000303|PubMed:15708861, ECO:0000303|PubMed:18266766}; AltName: Full=Sulfatase-modifying factor 2 {ECO:0000303|PubMed:15962010}; Flags: Precursor;+++[A0A024RDK8_HUMAN|Unreviewed]SubName: Full=Sulfatase modifying factor 2, isoform CRA_f {ECO:0000313|EMBL:EAX07982.1};+++[A0A0S2Z548_HUMAN|Unreviewed]SubName: Full=Sulfatase modifying factor 2 isoform 3 {ECO:0000313|EMBL:ALQ34042.1};+++[A0A0S2Z5C4_HUMAN|Unreviewed]SubName: Full=Sulfatase modifying factor 2 isoform 4 {ECO:0000313|EMBL:ALQ34043.1};+++[A0A0S2Z5Q3_HUMAN|Unreviewed]SubName: Full=Sulfatase modifying factor 2 isoform 2 {ECO:0000313|EMBL:ALQ34041.1};+++[A8MXB9_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000378824};+++[C9J660_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000406445};+++[C9JL30_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000414434}; Flags: Fragment;+++[E9PBT8_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000415989};+++[E9PG02_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000395554};+++[F8WA42_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000341938};+++[F8WCW9_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000415322};+++[F8WES7_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000393423};+++[F8WEV7_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000407954};+++[F8WEX5_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000407832};+++[H7C3B2_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000410796}; Flags: Fragment;+++[J3KQJ1_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000400922};+++[J3QT17_HUMAN|Unreviewed]SubName: Full=Inactive C-alpha-formylglycine-generating enzyme 2 {ECO:0000313|Ensembl:ENSP00000378823};"]
[25875,"'LETMD1'",397,328,299,341.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005741///mitochondrial outer membrane","GO:0005515///protein binding+++GO:0043022///ribosome binding","GO:0006875///cellular metal ion homeostasis","LETM1 domain containing 1","[LTMD1_HUMAN|Reviewed]RecName: Full=LETM1 domain-containing protein 1; AltName: Full=Cervical cancer 1 proto-oncogene protein p40; AltName: Full=Cervical cancer proto-oncogene 2 protein; AltName: Full=HCCR-1; AltName: Full=HCRR-2;+++[F8VP71_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450333};+++[F8VPY5_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450275}; Flags: Fragment;+++[F8VQE7_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450082}; Flags: Fragment;+++[F8VR33_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450391}; Flags: Fragment;+++[F8VR35_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450390};+++[F8VS60_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000448222}; Flags: Fragment;+++[F8VTR1_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000448110}; Flags: Fragment;+++[F8VUZ8_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000449681};+++[F8VVQ3_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000449896}; Flags: Fragment;+++[F8VXQ4_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000448800};+++[F8VZA2_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000446862}; Flags: Fragment;+++[F8W0R0_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000447166}; Flags: Fragment;+++[F8W1U1_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000447420};+++[F8W1Z2_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000447419};+++[F8W6J0_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000369478};+++[F8WCD9_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000448442};+++[H0YH93_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000446551}; Flags: Fragment;+++[H0YHF4_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000446967}; Flags: Fragment;+++[H0YIV5_HUMAN|Unreviewed]SubName: Full=LETM1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450251}; Flags: Fragment;"]
[25893,"'TRIM58'",196.14,187,171,184.713333333333,"04740///Olfactory transduction+++04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005622///intracellular","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003674///molecular_function+++GO:0045505///dynein intermediate chain binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0045504///dynein heavy chain binding+++GO:0016740///transferase activity","GO:0000209///protein polyubiquitination+++GO:1902838///regulation of nuclear migration along microtubule+++GO:0008150///biological_process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0061931///positive regulation of erythrocyte enucleation+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination","tripartite motif containing 58","[TRI58_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM58; EC=2.3.2.27; AltName: Full=Protein BIA2; AltName: Full=RING-type E3 ubiquitin transferase TRIM58 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 58;"]
[25913,"'POT1'",228,202,173,201,"04137///Mitophagy - animal+++04140///Autophagy - animal",null,"M00424///Shelterin complex",null,"GO:0005694///chromosome+++GO:0000783///nuclear telomere cap complex+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0070187///shelterin complex+++GO:0005654///nucleoplasm","GO:0017151///DEAD/H-box RNA helicase binding+++GO:1905773///8-hydroxy-2'-deoxyguanosine DNA binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0042162///telomeric DNA binding+++GO:0061849///telomeric G-quadruplex DNA binding+++GO:0003677///DNA binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:1990955///G-rich single-stranded DNA binding+++GO:0061821///telomeric D-loop binding+++GO:0005515///protein binding+++GO:0010521///telomerase inhibitor activity","GO:0051096///positive regulation of helicase activity+++GO:0000723///telomere maintenance+++GO:0061820///telomeric D-loop disassembly+++GO:0032202///telomere assembly+++GO:0060383///positive regulation of DNA strand elongation+++GO:0007004///telomere maintenance via telomerase+++GO:0016233///telomere capping+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051974///negative regulation of telomerase activity+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0032508///DNA duplex unwinding+++GO:0070200///establishment of protein localization to telomere+++GO:1905776///positive regulation of DNA helicase activity+++GO:1905774///regulation of DNA helicase activity+++GO:0032210///regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity","protection of telomeres 1","[POTE1_HUMAN|Reviewed]RecName: Full=Protection of telomeres protein 1; Short=hPot1; AltName: Full=POT1-like telomere end-binding protein;+++[A0A024R739_HUMAN|Unreviewed]SubName: Full=POT1 protection of telomeres 1 homolog (S. pombe), isoform CRA_b {ECO:0000313|EMBL:EAW83617.1};+++[A8MTK3_HUMAN|Unreviewed]SubName: Full=POT1 protection of telomeres 1 homolog (S. pombe), isoform CRA_a {ECO:0000313|EMBL:EAW83615.1}; SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000377002};+++[B7Z7M5_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000476981}; SubName: Full=cDNA FLJ58706, highly similar to Protection of telomeres 1 {ECO:0000313|EMBL:BAH13661.1};+++[C9JPG9_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000388921}; Flags: Fragment;+++[H7C0Z6_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000397632}; Flags: Fragment;+++[H7C4C7_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000416820}; Flags: Fragment;+++[Q5MJ33_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 variant 4 {ECO:0000313|EMBL:AAW22616.1};+++[Q5MJ34_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 variant 3 {ECO:0000313|EMBL:AAW22615.1};+++[Q5MJ35_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 variant 2 {ECO:0000313|EMBL:AAW22614.1};+++[V9GY10_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000476290}; Flags: Fragment;+++[V9GYE6_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000476673}; Flags: Fragment;+++[V9GZ00_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000477258}; Flags: Fragment;+++[V9GZ21_HUMAN|Unreviewed]SubName: Full=Protection of telomeres protein 1 {ECO:0000313|Ensembl:ENSP00000477320}; Flags: Fragment;"]
[25925,"'ZNF521'",508,539,383,476.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0007275///multicellular organism development+++GO:0048663///neuron fate commitment+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation","zinc finger protein 521","[ZN521_HUMAN|Reviewed]RecName: Full=Zinc finger protein 521; AltName: Full=Early hematopoietic zinc finger protein; AltName: Full=LYST-interacting protein 3;+++[H7BYU6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSP00000382352};+++[J3KSZ4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSP00000462724}; Flags: Fragment;+++[J3KT07_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSP00000462746}; Flags: Fragment;+++[J3KTI4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSP00000463000};+++[J3QQI2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSP00000463748}; Flags: Fragment;+++[J3QRW6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 521 {ECO:0000313|Ensembl:ENSP00000464415}; Flags: Fragment;+++[Q8IYZ2_HUMAN|Unreviewed]SubName: Full=ZNF521 protein {ECO:0000313|EMBL:AAH32869.2}; Flags: Fragment;"]
[25938,"'HEATR5A'",1126,1010,751.49,962.496666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0030139///endocytic vesicle",null,"GO:0006897///endocytosis+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0008104///protein localization","HEAT repeat containing 5A","[HTR5A_HUMAN|Reviewed]RecName: Full=HEAT repeat-containing protein 5A;+++[F5H619_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 5A {ECO:0000313|Ensembl:ENSP00000437968};+++[F8VQQ6_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 5A {ECO:0000313|Ensembl:ENSP00000450262}; Flags: Fragment;+++[H0YHE0_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 5A {ECO:0000313|Ensembl:ENSP00000446884}; Flags: Fragment;+++[H0YHS5_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 5A {ECO:0000313|Ensembl:ENSP00000447708}; Flags: Fragment;+++[H0YIW3_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 5A {ECO:0000313|Ensembl:ENSP00000450296}; Flags: Fragment;+++[H7C5W6_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 5A {ECO:0000313|Ensembl:ENSP00000439979}; Flags: Fragment;"]
[25960,"'ADGRA2'",3099,2692,2282,2691,"04144///Endocytosis",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0009986///cell surface+++GO:1990909///Wnt signalosome+++GO:0030175///filopodium+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:0010595///positive regulation of endothelial cell migration+++GO:0016055///Wnt signaling pathway+++GO:0043542///endothelial cell migration+++GO:0050920///regulation of chemotaxis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0001525///angiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0007165///signal transduction+++GO:0007417///central nervous system development+++GO:0090210///regulation of establishment of blood-brain barrier+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0045765///regulation of angiogenesis","adhesion G protein-coupled receptor A2","[AGRA2_HUMAN|Reviewed]RecName: Full=Adhesion G protein-coupled receptor A2 {ECO:0000312|HGNC:HGNC:17849}; AltName: Full=G-protein coupled receptor 124 {ECO:0000312|HGNC:HGNC:17849}; AltName: Full=Tumor endothelial marker 5 {ECO:0000303|PubMed:11559528}; Flags: Precursor;+++[A0A172Q385_HUMAN|Unreviewed]SubName: Full=Tumor endothelial marker 5 {ECO:0000313|EMBL:AND76657.1}; Flags: Fragment;+++[D3DSW5_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 124, isoform CRA_a {ECO:0000313|EMBL:EAW63359.1};+++[H7C1L1_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor A2 {ECO:0000313|Ensembl:ENSP00000400860}; Flags: Fragment;+++[Q6YN44_HUMAN|Unreviewed]SubName: Full=Tumor endothelial marker 5 {ECO:0000313|EMBL:AAM09084.1}; Flags: Fragment;"]
[25981,"'DNAH1'",184,187,142,171,"05016///Huntington's disease","H01282///Spermatogenic failure+++H00564///Primary ciliary dyskinesia",null,null,"GO:0005858///axonemal dynein complex+++GO:0005856///cytoskeleton+++GO:0005930///axoneme+++GO:0005929///cilium+++GO:0030286///dynein complex+++GO:0036126///sperm flagellum+++GO:0005874///microtubule+++GO:0031514///motile cilium+++GO:0036156///inner dynein arm+++GO:0042995///cell projection+++GO:0005737///cytoplasm","GO:0051959///dynein light intermediate chain binding+++GO:0005524///ATP binding+++GO:0003777///microtubule motor activity+++GO:0045505///dynein intermediate chain binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0000166///nucleotide binding+++GO:0003774///motor activity+++GO:0045503///dynein light chain binding+++GO:0016887///ATPase activity","GO:0003351///epithelial cilium movement+++GO:0030317///flagellated sperm motility+++GO:0007288///sperm axoneme assembly+++GO:0036159///inner dynein arm assembly+++GO:0060285///cilium-dependent cell motility+++GO:0060294///cilium movement involved in cell motility+++GO:0003341///cilium movement+++GO:0007018///microtubule-based movement","dynein axonemal heavy chain 1","[DYH1_HUMAN|Reviewed]RecName: Full=Dynein heavy chain 1, axonemal; AltName: Full=Axonemal beta dynein heavy chain 1; AltName: Full=Ciliary dynein heavy chain 1; AltName: Full=Heat shock regulated protein 1; Short=HSRF-1; AltName: Full=hDHC7;+++[A0A140VJI6_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 60 {ECO:0000313|EMBL:AEE60973.1};+++[H7C506_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000418688}; Flags: Fragment;+++[H7C563_HUMAN|Unreviewed]SubName: Full=Dynein heavy chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000419071}; Flags: Fragment;"]
[26005,"'C2CD3'",1185,1204,1111,1166.66666666667,{"$nulls":4},"GO:0034451///centriolar satellite+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0036064///ciliary basal body+++GO:0005813///centrosome","GO:0005515///protein binding","GO:0060271///cilium assembly+++GO:0071539///protein localization to centrosome+++GO:0030162///regulation of proteolysis+++GO:0030030///cell projection organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0008589///regulation of smoothened signaling pathway+++GO:0021915///neural tube development+++GO:0007389///pattern specification process+++GO:1905515///non-motile cilium assembly+++GO:0042733///embryonic digit morphogenesis+++GO:0001701///in utero embryonic development+++GO:0061511///centriole elongation+++GO:0016485///protein processing+++GO:0030326///embryonic limb morphogenesis+++GO:0001947///heart looping+++GO:0021997///neural plate axis specification+++GO:0007420///brain development","C2 calcium dependent domain containing 3","[C2CD3_HUMAN|Reviewed]RecName: Full=C2 domain-containing protein 3;+++[F5H0U2_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000445933};+++[H0YFM6_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000439343}; Flags: Fragment;+++[H0YG44_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000441742}; Flags: Fragment;+++[H7BZB4_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000388750}; Flags: Fragment;+++[H7C288_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000404577}; Flags: Fragment;"]
[26031,"'OSBPL3'",503,701,528,577.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0032433///filopodium tip+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0042995///cell projection","GO:0008289///lipid binding+++GO:0015485///cholesterol binding+++GO:0032934///sterol binding+++GO:0005515///protein binding+++GO:0015248///sterol transporter activity","GO:0015918///sterol transport+++GO:0006869///lipid transport+++GO:0006699///bile acid biosynthetic process","oxysterol binding protein like 3","[OSBL3_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 3; Short=ORP-3; Short=OSBP-related protein 3;+++[C9J8P4_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 3 {ECO:0000313|Ensembl:ENSP00000411249}; Flags: Fragment;+++[C9JEF2_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 3 {ECO:0000313|Ensembl:ENSP00000403374}; Flags: Fragment;+++[C9JZ19_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 3 {ECO:0000313|Ensembl:ENSP00000407829}; Flags: Fragment;"]
[260436,"'FDCSP'",221,266,466,317.666666666667,{"$nulls":4},"GO:0005576///extracellular region",null,null,"follicular dendritic cell secreted protein","[FDSCP_HUMAN|Reviewed]RecName: Full=Follicular dendritic cell secreted peptide; Short=FDC secreted protein; Short=FDC-SP; Flags: Precursor;+++[Q540F3_HUMAN|Unreviewed]SubName: Full=Chromosome 4 open reading frame 7 {ECO:0000313|EMBL:EAX05613.1}; SubName: Full=NPC-associated peptide {ECO:0000313|EMBL:AAO41714.1};"]
[26071,"'RTL8A'",1190,1591,1683,1488,{"$nulls":4},"GO:0005886///plasma membrane","GO:0005515///protein binding",null,"retrotransposon Gag like 8A","[RTL8A_HUMAN|Reviewed]RecName: Full=Retrotransposon Gag-like protein 8A {ECO:0000312|HGNC:HGNC:24514}; AltName: Full=Mammalian retrotransposon derived protein 8A;+++[Q6IPB9_HUMAN|Unreviewed]SubName: Full=FAM127B protein {ECO:0000313|EMBL:AAH71991.2}; Flags: Fragment;"]
[26097,"'CHTOP'",273,251,318,280.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0000346///transcription export complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0008327///methyl-CpG binding+++GO:0003723///RNA binding","GO:0006406///mRNA export from nucleus+++GO:0051028///mRNA transport+++GO:0032781///positive regulation of ATPase activity+++GO:0031124///mRNA 3'-end processing+++GO:0006405///RNA export from nucleus+++GO:0031062///positive regulation of histone methylation+++GO:0008284///positive regulation of cell proliferation+++GO:0051096///positive regulation of helicase activity","chromatin target of PRMT1","[CHTOP_HUMAN|Reviewed]RecName: Full=Chromatin target of PRMT1 protein; AltName: Full=Friend of PRMT1 protein; AltName: Full=Small arginine- and glycine-rich protein; Short=SRAG;+++[A0A087X1B7_HUMAN|Unreviewed]SubName: Full=Chromatin target of PRMT1 protein {ECO:0000313|Ensembl:ENSP00000484038};+++[Q5T7Y7_HUMAN|Unreviewed]SubName: Full=Chromatin target of PRMT1 protein {ECO:0000313|Ensembl:ENSP00000357675};+++[X6R700_HUMAN|Unreviewed]SubName: Full=Chromatin target of PRMT1 protein {ECO:0000313|Ensembl:ENSP00000357676};"]
[26145,"'IRF2BP1'",798,794,842,811.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","interferon regulatory factor 2 binding protein 1","[I2BP1_HUMAN|Reviewed]RecName: Full=Interferon regulatory factor 2-binding protein 1; Short=IRF-2-binding protein 1; Short=IRF-2BP1; AltName: Full=Probable E3 ubiquitin-protein ligase IRF2BP1; EC=2.3.2.27; AltName: Full=Probable RING-type E3 ubiquitin transferase IRF2BP1 {ECO:0000305};"]
[26160,"'IFT172'",565,501,417,494.333333333333,null,"H02157///Short-rib thoracic dysplasia+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0097228///sperm principal piece+++GO:0097225///sperm midpiece+++GO:0005929///cilium+++GO:0097598///sperm cytoplasmic droplet+++GO:0042995///cell projection+++GO:0036064///ciliary basal body+++GO:0030992///intraciliary transport particle B+++GO:1903561///extracellular vesicle+++GO:0005930///axoneme+++GO:0097542///ciliary tip","GO:0003677///DNA binding","GO:0007275///multicellular organism development+++GO:0021915///neural tube development+++GO:0001843///neural tube closure+++GO:0060173///limb development+++GO:0001947///heart looping+++GO:0007224///smoothened signaling pathway+++GO:0060348///bone development+++GO:0007507///heart development+++GO:0001841///neural tube formation+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0021522///spinal cord motor neuron differentiation+++GO:0060271///cilium assembly+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007420///brain development+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0060021///roof of mouth development+++GO:1905515///non-motile cilium assembly+++GO:0007219///Notch signaling pathway+++GO:0061525///hindgut development+++GO:0008544///epidermis development+++GO:0009953///dorsal/ventral pattern formation+++GO:0070986///left/right axis specification+++GO:0031122///cytoplasmic microtubule organization+++GO:0008589///regulation of smoothened signaling pathway+++GO:0016485///protein processing+++GO:0007368///determination of left/right symmetry","intraflagellar transport 172","[IF172_HUMAN|Reviewed]RecName: Full=Intraflagellar transport protein 172 homolog;+++[F5GZ56_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 172 homolog {ECO:0000313|Ensembl:ENSP00000407408};+++[H0YAI8_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 172 homolog {ECO:0000313|Ensembl:ENSP00000427255}; Flags: Fragment;+++[H7C161_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 172 homolog {ECO:0000313|Ensembl:ENSP00000398633}; Flags: Fragment;+++[H7C186_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 172 homolog {ECO:0000313|Ensembl:ENSP00000399017}; Flags: Fragment;+++[H7C252_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 172 homolog {ECO:0000313|Ensembl:ENSP00000404082}; Flags: Fragment;+++[L8E9V2_HUMAN|Unreviewed]SubName: Full=Alternative protein IFT172 {ECO:0000313|EMBL:CCQ43521.1};"]
[26211,"'OR2F1'",0,0,2,0.666666666666667,"04740///Olfactory transduction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004984///olfactory receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0050896///response to stimulus+++GO:0007608///sensory perception of smell+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","olfactory receptor family 2 subfamily F member 1 (gene/pseudogene)","[OR2F1_HUMAN|Reviewed]RecName: Full=Olfactory receptor 2F1; AltName: Full=Olfactory receptor 2F3; AltName: Full=Olfactory receptor 2F4; AltName: Full=Olfactory receptor 2F5; AltName: Full=Olfactory receptor-like protein OLF3;+++[A0A126GV98_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GWI1_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GWI5_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GWK3_HUMAN|Unreviewed]SubName: Full=OR2F1 {ECO:0000313|EMBL:ALI87788.1};+++[A0A126GWK4_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[L8E9J5_HUMAN|Unreviewed]SubName: Full=Alternative protein OR2F1 {ECO:0000313|EMBL:CCQ43411.1};+++[O43886_HUMAN|Unreviewed]SubName: Full=Olfactory receptor {ECO:0000313|EMBL:AAC39631.1}; Flags: Fragment;+++[O43887_HUMAN|Unreviewed]SubName: Full=Olfactory receptor {ECO:0000313|EMBL:AAC39632.1}; Flags: Fragment;"]
[26233,"'FBXL6'",148,155,258,187,{"$nulls":4},"GO:0019005///SCF ubiquitin ligase complex","GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0006508///proteolysis+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination","F-box and leucine rich repeat protein 6","[FBXL6_HUMAN|Reviewed]RecName: Full=F-box/LRR-repeat protein 6; AltName: Full=F-box and leucine-rich repeat protein 6; AltName: Full=F-box protein FBL6; AltName: Full=FBL6A;+++[Q71RB6_HUMAN|Unreviewed]SubName: Full=F-box and leucine-rich repeat protein 6, isoform CRA_d {ECO:0000313|EMBL:EAW82120.1}; SubName: Full=PP14630 {ECO:0000313|EMBL:AAQ15258.1};"]
[26271,"'FBXO5'",30,27,23,26.6666666666667,"04114///Oocyte meiosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0072687///meiotic spindle+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005819///spindle","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:1990948///ubiquitin ligase inhibitor activity+++GO:0010997///anaphase-promoting complex binding","GO:0045841///negative regulation of mitotic metaphase/anaphase transition+++GO:1905322///positive regulation of mesenchymal stem cell migration+++GO:0032876///negative regulation of DNA endoreduplication+++GO:0040020///regulation of meiotic nuclear division+++GO:0016050///vesicle organization+++GO:0045835///negative regulation of meiotic nuclear division+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0016567///protein ubiquitination+++GO:2001021///negative regulation of response to DNA damage stimulus+++GO:0001556///oocyte maturation+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0045669///positive regulation of osteoblast differentiation+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0070169///positive regulation of biomineral tissue development+++GO:2000773///negative regulation of cellular senescence+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0007049///cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0046785///microtubule polymerization+++GO:0007346///regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0051225///spindle assembly+++GO:0007057///spindle assembly involved in female meiosis I+++GO:0006275///regulation of DNA replication","F-box protein 5","[FBX5_HUMAN|Reviewed]RecName: Full=F-box only protein 5 {ECO:0000305}; AltName: Full=Early mitotic inhibitor 1 {ECO:0000303|PubMed:15148369};"]
[26284,"'ERAL1'",571,620,660,617,null,"H02095///Perrault syndrome",null,null,"GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0019843///rRNA binding+++GO:0043024///ribosomal small subunit binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding","GO:0070125///mitochondrial translational elongation+++GO:0000028///ribosomal small subunit assembly+++GO:0042254///ribosome biogenesis+++GO:0070126///mitochondrial translational termination","Era like 12S mitochondrial rRNA chaperone 1","[ERAL1_HUMAN|Reviewed]RecName: Full=GTPase Era, mitochondrial; Short=H-ERA; Short=hERA; AltName: Full=Conserved ERA-like GTPase; Short=CEGA; AltName: Full=ERA-W; AltName: Full=ERA-like protein 1; Flags: Precursor;+++[J3QRV9_HUMAN|Unreviewed]SubName: Full=GTPase Era, mitochondrial {ECO:0000313|Ensembl:ENSP00000464402}; Flags: Fragment;+++[J3QSB2_HUMAN|Unreviewed]SubName: Full=GTPase Era, mitochondrial {ECO:0000313|Ensembl:ENSP00000464607}; Flags: Fragment;+++[J3QT61_HUMAN|Unreviewed]SubName: Full=GTPase Era, mitochondrial {ECO:0000313|Ensembl:ENSP00000396125};+++[K7EQJ8_HUMAN|Unreviewed]SubName: Full=GTPase Era, mitochondrial {ECO:0000313|Ensembl:ENSP00000467860}; Flags: Fragment;"]
[2631,"'NIPSNAP2'",435,461,425,440.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006119///oxidative phosphorylation+++GO:0007005///mitochondrion organization+++GO:1901843///positive regulation of high voltage-gated calcium channel activity","nipsnap homolog 2","[NIPS2_HUMAN|Reviewed]RecName: Full=Protein NipSnap homolog 2; Short=NipSnap2; AltName: Full=Glioblastoma-amplified sequence {ECO:0000303|PubMed:9615231};+++[C9J7B1_HUMAN|Unreviewed]SubName: Full=Protein NipSnap homolog 2 {ECO:0000313|Ensembl:ENSP00000406336}; Flags: Fragment;+++[C9K068_HUMAN|Unreviewed]SubName: Full=Protein NipSnap homolog 2 {ECO:0000313|Ensembl:ENSP00000401185}; Flags: Fragment;+++[F8WBI5_HUMAN|Unreviewed]SubName: Full=Protein NipSnap homolog 2 {ECO:0000313|Ensembl:ENSP00000398498};+++[H7C333_HUMAN|Unreviewed]SubName: Full=Protein NipSnap homolog 2 {ECO:0000313|Ensembl:ENSP00000409266}; Flags: Fragment;"]
[2650,"'GCNT1'",62,48,51,53.6666666666667,"00512///Mucin type O-glycan biosynthesis+++01100///Metabolic pathways",null,"M00056///O-glycan biosynthesis, mucin type core","R05910///UDP-N-acetyl-D-glucosamine + Tn antigen <=> UDP + G00031+++R05912///UDP-N-acetyl-D-glucosamine + T antigen <=> UDP + G00025","GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0031985///Golgi cisterna+++GO:0005615///extracellular space","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008375///acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0003829///beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity","GO:0016266///O-glycan processing+++GO:0060993///kidney morphogenesis+++GO:0060352///cell adhesion molecule production+++GO:0006486///protein glycosylation+++GO:0048729///tissue morphogenesis+++GO:0032868///response to insulin+++GO:0009101///glycoprotein biosynthetic process+++GO:0050901///leukocyte tethering or rolling","glucosaminyl (N-acetyl) transferase 1, core 2","[GCNT1_HUMAN|Reviewed]RecName: Full=Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; EC=2.4.1.102; AltName: Full=Core 2-branching enzyme; AltName: Full=Core2-GlcNAc-transferase; Short=C2GNT; Short=Core 2 GNT;+++[L8E8T5_HUMAN|Unreviewed]SubName: Full=Alternative protein GCNT1 {ECO:0000313|EMBL:CCQ43141.1};+++[Q86T81_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451M2318 {ECO:0000313|EMBL:CAD89956.1};"]
[26511,"'CHIC2'",275,304,297.33,292.11,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005798///Golgi-associated vesicle+++GO:0016020///membrane+++GO:0005575///cellular_component","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0008150///biological_process","cysteine rich hydrophobic domain 2","[CHIC2_HUMAN|Reviewed]RecName: Full=Cysteine-rich hydrophobic domain-containing protein 2; AltName: Full=BrX-like translocated in leukemia;+++[D6RDW7_HUMAN|Unreviewed]SubName: Full=Cysteine-rich hydrophobic domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425238};+++[H0Y8H1_HUMAN|Unreviewed]SubName: Full=Cysteine-rich hydrophobic domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000421032}; Flags: Fragment;"]
[2660,"'MSTN'",0,0,1,0.333333333333333,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm","GO:0005102///signaling receptor binding+++GO:0005125///cytokine activity+++GO:0008201///heparin binding+++GO:0042803///protein homodimerization activity+++GO:0008083///growth factor activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0005160///transforming growth factor beta receptor binding","GO:0042981///regulation of apoptotic process+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0010759///positive regulation of macrophage chemotaxis+++GO:0051602///response to electrical stimulus+++GO:0043627///response to estrogen+++GO:0014850///response to muscle activity+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0010469///regulation of signaling receptor activity+++GO:1902725///negative regulation of satellite cell differentiation+++GO:0022602///ovulation cycle process+++GO:0060395///SMAD protein signal transduction+++GO:0048468///cell development+++GO:0048632///negative regulation of skeletal muscle tissue growth+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007517///muscle organ development+++GO:0051384///response to glucocorticoid+++GO:0043408///regulation of MAPK cascade+++GO:0046716///muscle cell cellular homeostasis+++GO:0045662///negative regulation of myoblast differentiation+++GO:0014732///skeletal muscle atrophy+++GO:0043403///skeletal muscle tissue regeneration+++GO:0009629///response to gravity+++GO:0009408///response to heat+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:1902723///negative regulation of skeletal muscle satellite cell proliferation+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0014839///myoblast migration involved in skeletal muscle regeneration+++GO:0033574///response to testosterone+++GO:2000818///negative regulation of myoblast proliferation+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0033673///negative regulation of kinase activity+++GO:0014741///negative regulation of muscle hypertrophy+++GO:0045471///response to ethanol","myostatin","[GDF8_HUMAN|Reviewed]RecName: Full=Growth/differentiation factor 8; Short=GDF-8; AltName: Full=Myostatin; Flags: Precursor;+++[A1C2E7_HUMAN|Unreviewed]SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48369.1};+++[A1C2E8_HUMAN|Unreviewed]SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48370.1};+++[A1C2F0_HUMAN|Unreviewed]SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48372.1};+++[A1C2F2_HUMAN|Unreviewed]SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48374.1};+++[A1C2F7_HUMAN|Unreviewed]SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48379.1};+++[A1C2G8_HUMAN|Unreviewed]SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48390.1};+++[A1C2K4_HUMAN|Unreviewed]SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48426.1};+++[Q53S46_HUMAN|Unreviewed]SubName: Full=Growth differentiation factor 8 {ECO:0000313|EMBL:EAX10880.1}; SubName: Full=Myostatin {ECO:0000313|EMBL:ABI48371.1}; SubName: Full=cDNA FLJ75269, highly similar to Homo sapiens myostatin (GDF8) mRNA {ECO:0000313|EMBL:BAF84213.1};"]
[266655,"'BRD3OS'",783,694,658,711.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0070577///lysine-acetylated histone binding+++GO:0003682///chromatin binding","GO:0006351///transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization","BRD3 opposite strand","[BRDOS_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein BRD3OS {ECO:0000305}; AltName: Full=BRD3 opposite strand protein {ECO:0000305}; AltName: Full=Long intergenic non-protein coding RNA 94 {ECO:0000312|HGNC:HGNC:24742}; AltName: Full=Non-protein coding RNA 94 {ECO:0000312|HGNC:HGNC:24742};+++[Q6XYD6_HUMAN|Unreviewed]SubName: Full=LP2477 {ECO:0000313|EMBL:AAP34457.1};"]
[2675,"'GFRA2'",618,247,381,415.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043235///receptor complex+++GO:0031225///anchored component of membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0019898///extrinsic component of membrane","GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0016167///glial cell-derived neurotrophic factor receptor activity+++GO:0038023///signaling receptor activity","GO:0007411///axon guidance+++GO:0000165///MAPK cascade+++GO:0035860///glial cell-derived neurotrophic factor receptor signaling pathway+++GO:0007399///nervous system development+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway","GDNF family receptor alpha 2","[GFRA2_HUMAN|Reviewed]RecName: Full=GDNF family receptor alpha-2; Short=GDNF receptor alpha-2; Short=GDNFR-alpha-2; Short=GFR-alpha-2; AltName: Full=GDNF receptor beta; Short=GDNFR-beta; AltName: Full=Neurturin receptor alpha; Short=NRTNR-alpha; Short=NTNR-alpha; AltName: Full=RET ligand 2; AltName: Full=TGF-beta-related neurotrophic factor receptor 2; Flags: Precursor;+++[E5RGR6_HUMAN|Unreviewed]SubName: Full=GDNF family receptor alpha-2 {ECO:0000313|Ensembl:ENSP00000428721}; Flags: Fragment;+++[E5RJ44_HUMAN|Unreviewed]SubName: Full=GDNF family receptor alpha-2 {ECO:0000313|Ensembl:ENSP00000430622}; Flags: Fragment;+++[J3KNF0_HUMAN|Unreviewed]SubName: Full=GDNF family receptor alpha-2 {ECO:0000313|Ensembl:ENSP00000306654};"]
[2690,"'GHR'",212,113,109,144.666666666667,"04060///Cytokine-cytokine receptor interaction+++04151///PI3K-Akt signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04630///Jak-STAT signaling pathway","H00254///Growth hormone deficiency+++H02037///Laron syndrome",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005829///cytosol+++GO:0070195///growth hormone receptor complex+++GO:0043025///neuronal cell body+++GO:0043235///receptor complex+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0019903///protein phosphatase binding+++GO:0017046///peptide hormone binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0019838///growth factor binding+++GO:0019955///cytokine binding+++GO:0070064///proline-rich region binding+++GO:0004896///cytokine receptor activity+++GO:0004903///growth hormone receptor activity+++GO:0042802///identical protein binding+++GO:0019901///protein kinase binding+++GO:0042169///SH2 domain binding","GO:0034097///response to cytokine+++GO:0042445///hormone metabolic process+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0019530///taurine metabolic process+++GO:0006897///endocytosis+++GO:0046898///response to cycloheximide+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043278///response to morphine+++GO:0009755///hormone-mediated signaling pathway+++GO:0009725///response to hormone+++GO:0031623///receptor internalization+++GO:0032869///cellular response to insulin stimulus+++GO:0042976///activation of Janus kinase activity+++GO:0007259///JAK-STAT cascade+++GO:0060351///cartilage development involved in endochondral bone morphogenesis+++GO:0040018///positive regulation of multicellular organism growth+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0032355///response to estradiol+++GO:0040014///regulation of multicellular organism growth+++GO:0060396///growth hormone receptor signaling pathway+++GO:0000187///activation of MAPK activity+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0032094///response to food+++GO:0060416///response to growth hormone+++GO:0032870///cellular response to hormone stimulus+++GO:0043434///response to peptide hormone+++GO:0070555///response to interleukin-1+++GO:0051384///response to glucocorticoid+++GO:1901215///negative regulation of neuron death+++GO:0045597///positive regulation of cell differentiation+++GO:0048009///insulin-like growth factor receptor signaling pathway","growth hormone receptor","[GHR_HUMAN|Reviewed]RecName: Full=Growth hormone receptor; Short=GH receptor; AltName: Full=Somatotropin receptor; Contains: RecName: Full=Growth hormone-binding protein; Short=GH-binding protein; Short=GHBP; AltName: Full=Serum-binding protein; Flags: Precursor;+++[A0A087X0H5_HUMAN|Unreviewed]SubName: Full=Growth hormone receptor {ECO:0000313|Ensembl:ENSP00000483403};+++[A0A087X162_HUMAN|Unreviewed]SubName: Full=Growth hormone receptor {ECO:0000313|Ensembl:ENSP00000483926};+++[B9EGJ3_HUMAN|Unreviewed]SubName: Full=GHR protein {ECO:0000313|EMBL:AAI36497.1};+++[E7ES05_HUMAN|Unreviewed]SubName: Full=Growth hormone receptor {ECO:0000313|Ensembl:ENSP00000422333};+++[E9PCN7_HUMAN|Unreviewed]SubName: Full=Growth hormone receptor {ECO:0000313|Ensembl:ENSP00000426739};+++[Q9HCW9_HUMAN|Unreviewed]SubName: Full=Growth hormone receptor {ECO:0000313|EMBL:CAC06615.1}; Flags: Fragment;+++[Q9NRZ8_HUMAN|Unreviewed]SubName: Full=Growth hormone receptor {ECO:0000313|EMBL:AAF71399.1}; Flags: Fragment;"]
[26999,"'CYFIP2'",2142,2426,2042,2203.33333333333,"04810///Regulation of actin cytoskeleton+++03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0030054///cell junction+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0031209///SCAR complex+++GO:0045202///synapse","GO:0005515///protein binding+++GO:0000340///RNA 7-methylguanosine cap binding","GO:0030031///cell projection assembly+++GO:0097202///activation of cysteine-type endopeptidase activity+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0045862///positive regulation of proteolysis+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0097484///dendrite extension+++GO:0000902///cell morphogenesis+++GO:0031175///neuron projection development+++GO:0098609///cell-cell adhesion+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0007411///axon guidance+++GO:0007155///cell adhesion+++GO:0006915///apoptotic process","cytoplasmic FMR1 interacting protein 2","[CYFP2_HUMAN|Reviewed]RecName: Full=Cytoplasmic FMR1-interacting protein 2; AltName: Full=p53-inducible protein 121;+++[A0A087WTQ3_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000478058}; Flags: Fragment;+++[A0A087WV63_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000479211};+++[A0A087WVE1_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000479376}; Flags: Fragment;+++[A0A087WWZ1_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000480605}; Flags: Fragment;+++[A0A087WZL7_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000482739}; Flags: Fragment;+++[B7Z8N7_HUMAN|Unreviewed]RecName: Full=Cytoplasmic FMR1-interacting protein {ECO:0000256|PIRNR:PIRNR008153};+++[E5RKA3_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000428079};+++[E7EVJ5_HUMAN|Unreviewed]RecName: Full=Cytoplasmic FMR1-interacting protein {ECO:0000256|PIRNR:PIRNR008153};+++[E7EW33_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000428009};+++[H7C229_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000403793};+++[L0R6F7_HUMAN|Unreviewed]SubName: Full=Alternative protein CYFIP2 {ECO:0000313|EMBL:CCO13717.1};"]
[27020,"'NPTN'",3015,3523,3014,3184,{"$nulls":4},"GO:0097060///synaptic membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0014069///postsynaptic density+++GO:0060077///inhibitory synapse+++GO:0098978///glutamatergic synapse+++GO:0030425///dendrite+++GO:0016021///integral component of membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0009986///cell surface+++GO:0042734///presynaptic membrane+++GO:0098982///GABA-ergic synapse+++GO:0030424///axon","GO:0005105///type 1 fibroblast growth factor receptor binding+++GO:0098632///cell-cell adhesion mediator activity+++GO:0050839///cell adhesion molecule binding+++GO:0044325///ion channel binding+++GO:0005104///fibroblast growth factor receptor binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0010976///positive regulation of neuron projection development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1904861///excitatory synapse assembly+++GO:0001934///positive regulation of protein phosphorylation+++GO:0099557///trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission+++GO:0007155///cell adhesion+++GO:0008542///visual learning+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0060291///long-term synaptic potentiation+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0048170///positive regulation of long-term neuronal synaptic plasticity+++GO:1902683///regulation of receptor localization to synapse+++GO:0070593///dendrite self-avoidance+++GO:1903829///positive regulation of cellular protein localization+++GO:0007411///axon guidance+++GO:0007399///nervous system development+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:0050808///synapse organization+++GO:0050804///modulation of chemical synaptic transmission","neuroplastin","[NPTN_HUMAN|Reviewed]RecName: Full=Neuroplastin; AltName: Full=Stromal cell-derived receptor 1; Short=SDR-1; Flags: Precursor;+++[H3BQ94_HUMAN|Unreviewed]SubName: Full=Neuroplastin {ECO:0000313|Ensembl:ENSP00000455671}; Flags: Fragment;+++[H3BU51_HUMAN|Unreviewed]SubName: Full=Neuroplastin {ECO:0000313|Ensembl:ENSP00000457470};+++[Q9UFM8_HUMAN|Unreviewed]SubName: Full=Neuroplastin {ECO:0000313|Ensembl:ENSP00000456033}; Flags: Fragment;"]
[27069,"'GHITM'",1121,1193,1098,1137.33333333333,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0008150///biological_process","growth hormone inducible transmembrane protein","[GHITM_HUMAN|Reviewed]RecName: Full=Growth hormone-inducible transmembrane protein; AltName: Full=Dermal papilla-derived protein 2; AltName: Full=Mitochondrial morphology and cristae structure 1; Short=MICS1; AltName: Full=Transmembrane BAX inhibitor motif-containing protein 5; Flags: Precursor;+++[Q6FIA7_HUMAN|Unreviewed]SubName: Full=GHITM protein {ECO:0000313|EMBL:CAG38550.1};"]
[27098,"'CLUL1'",292,248,246,262,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005634///nucleus","GO:0051787///misfolded protein binding",null,"clusterin like 1","[CLUL1_HUMAN|Reviewed]RecName: Full=Clusterin-like protein 1; AltName: Full=Retinal-specific clusterin-like protein; Flags: Precursor;+++[B7Z5R4_HUMAN|Unreviewed]RecName: Full=Clusterin {ECO:0000256|RuleBase:RU000629};+++[F5GWQ8_HUMAN|Unreviewed]RecName: Full=Clusterin {ECO:0000256|RuleBase:RU000629};+++[J3QKW8_HUMAN|Unreviewed]RecName: Full=Clusterin {ECO:0000256|RuleBase:RU000629};+++[R4GN76_HUMAN|Unreviewed]SubName: Full=Clusterin-like protein 1 {ECO:0000313|Ensembl:ENSP00000473520}; Flags: Fragment;+++[R4GN95_HUMAN|Unreviewed]SubName: Full=Clusterin-like protein 1 {ECO:0000313|Ensembl:ENSP00000473543}; Flags: Fragment;"]
[27123,"'DKK2'",0,1,0,0.333333333333333,"04310///Wnt signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0039706///co-receptor binding+++GO:0048019///receptor antagonist activity","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:1900116///extracellular negative regulation of signal transduction+++GO:0007275///multicellular organism development","dickkopf WNT signaling pathway inhibitor 2","[DKK2_HUMAN|Reviewed]RecName: Full=Dickkopf-related protein 2; Short=Dickkopf-2; Short=Dkk-2; Short=hDkk-2; Flags: Precursor;+++[D6RCC2_HUMAN|Unreviewed]SubName: Full=Dickkopf-related protein 2 {ECO:0000313|Ensembl:ENSP00000423797};+++[D6RGF1_HUMAN|Unreviewed]SubName: Full=Dickkopf-related protein 2 {ECO:0000313|Ensembl:ENSP00000421255};+++[Q9H3R7_HUMAN|Unreviewed]SubName: Full=Dickkopf homolog 2 (Xenopus laevis), isoform CRA_a {ECO:0000313|EMBL:EAX06208.1}; SubName: Full=Dickkopf-2 variant {ECO:0000313|EMBL:BAB20420.1};"]
[27152,"'INTU'",88,110,73,90.3333333333333,{"$nulls":4},"GO:0009986///cell surface+++GO:0036064///ciliary basal body+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0031514///motile cilium","GO:0005515///protein binding","GO:0008589///regulation of smoothened signaling pathway+++GO:0060271///cilium assembly+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0030216///keratinocyte differentiation+++GO:0044458///motile cilium assembly+++GO:0021915///neural tube development+++GO:0030030///cell projection organization+++GO:1905515///non-motile cilium assembly+++GO:0001736///establishment of planar polarity+++GO:0007275///multicellular organism development+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:0030278///regulation of ossification+++GO:0060173///limb development+++GO:0042733///embryonic digit morphogenesis+++GO:0021513///spinal cord dorsal/ventral patterning+++GO:0007399///nervous system development+++GO:0051782///negative regulation of cell division+++GO:0031069///hair follicle morphogenesis","inturned planar cell polarity protein","[INTU_HUMAN|Reviewed]RecName: Full=Protein inturned; AltName: Full=Inturned planar cell polarity effector homolog; AltName: Full=PDZ domain-containing protein 6;+++[H0YA54_HUMAN|Unreviewed]SubName: Full=Protein inturned {ECO:0000313|Ensembl:ENSP00000426171}; Flags: Fragment;+++[H0YAI1_HUMAN|Unreviewed]SubName: Full=Protein inturned {ECO:0000313|Ensembl:ENSP00000427150}; Flags: Fragment;+++[J3QTA5_HUMAN|Unreviewed]SubName: Full=Protein inturned {ECO:0000313|Ensembl:ENSP00000422550}; Flags: Fragment;"]
[27185,"'DISC1'",37,37,55,43,null,"H01649///Schizophrenia",null,null,"GO:0030054///cell junction+++GO:0005739///mitochondrion+++GO:0005815///microtubule organizing center+++GO:0045202///synapse+++GO:0005874///microtubule+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0045111///intermediate filament cytoskeleton+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0014069///postsynaptic density+++GO:0097546///ciliary base","GO:0005515///protein binding","GO:0030177///positive regulation of Wnt signaling pathway+++GO:0000226///microtubule cytoskeleton organization+++GO:0001764///neuron migration+++GO:0032091///negative regulation of protein binding+++GO:0002052///positive regulation of neuroblast proliferation+++GO:1905515///non-motile cilium assembly+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0007399///nervous system development","DISC1 scaffold protein","[DISC1_HUMAN|Reviewed]RecName: Full=Disrupted in schizophrenia 1 protein;+++[A0A075B6Q7_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000403888}; SubName: Full=Disrupted in schizophrenia 1, isoform CRA_a {ECO:0000313|EMBL:EAW69966.1};+++[A0A087WYX6_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000482174};+++[A7E2W8_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 {ECO:0000313|EMBL:AAI51226.1};+++[C4P092_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 28 {ECO:0000313|EMBL:ACR40064.1}; SubName: Full=Disrupted in schizophrenia 1 isoform 39 {ECO:0000313|EMBL:ACR40075.1}; SubName: Full=Disrupted in schizophrenia 1 isoform 4 {ECO:0000313|EMBL:ACR40041.1}; SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000355592};+++[C4P093_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 14 {ECO:0000313|EMBL:ACR40051.1}; SubName: Full=Disrupted in schizophrenia 1 isoform 18 {ECO:0000313|EMBL:ACR40055.1}; SubName: Full=Disrupted in schizophrenia 1 isoform 31 {ECO:0000313|EMBL:ACR40067.1}; SubName: Full=Disrupted in schizophrenia 1 isoform 5 {ECO:0000313|EMBL:ACR40042.1}; SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000295051};+++[C4P094_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 6 {ECO:0000313|EMBL:ACR40043.1};+++[C4P096_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 8 {ECO:0000313|EMBL:ACR40045.1};+++[C4P098_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 10 {ECO:0000313|EMBL:ACR40047.1};+++[C4P0A0_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 12 {ECO:0000313|EMBL:ACR40049.1}; SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000481791};+++[C4P0A4_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 16 {ECO:0000313|EMBL:ACR40053.1};+++[C4P0A5_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 17 {ECO:0000313|EMBL:ACR40054.1}; SubName: Full=Disrupted in schizophrenia 1 isoform 32 {ECO:0000313|EMBL:ACR40068.1};+++[C4P0A9_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 21 {ECO:0000313|EMBL:ACR40058.1};+++[C4P0B0_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 23 {ECO:0000313|EMBL:ACR40059.1}; SubName: Full=Disrupted in schizophrenia 1 isoform 36 {ECO:0000313|EMBL:ACR40072.1}; SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000441193};+++[C4P0B1_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 24 {ECO:0000313|EMBL:ACR40060.1}; SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000440909};+++[C4P0B2_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 25 {ECO:0000313|EMBL:ACR40061.1};+++[C4P0C4_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 37 {ECO:0000313|EMBL:ACR40073.1};+++[C4P0C7_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 40 {ECO:0000313|EMBL:ACR40076.1};+++[C4P0C8_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 41 {ECO:0000313|EMBL:ACR40077.1};+++[C4P0D0_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 43 {ECO:0000313|EMBL:ACR40079.1};+++[C4P0D1_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 44 {ECO:0000313|EMBL:ACR40080.1};+++[C4P0D2_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 45 {ECO:0000313|EMBL:ACR40081.1};+++[C4P0D3_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform 46 {ECO:0000313|EMBL:ACR40082.1};+++[H0Y7U2_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000415147};+++[Q5T409_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 protein {ECO:0000313|Ensembl:ENSP00000355597};+++[X5DQV8_HUMAN|Unreviewed]SubName: Full=Disrupted in schizophrenia 1 isoform A {ECO:0000313|EMBL:AHW56462.1}; Flags: Fragment;"]
[27237,"'ARHGEF16'",12,16,11,13,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0045296///cadherin binding+++GO:0017048///Rho GTPase binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0035023///regulation of Rho protein signal transduction+++GO:0090630///activation of GTPase activity+++GO:0060326///cell chemotaxis+++GO:0043065///positive regulation of apoptotic process+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho guanine nucleotide exchange factor 16","[ARHGG_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 16; AltName: Full=Ephexin-4;+++[A0A2X0SFX5_HUMAN|Unreviewed]SubName: Full=ARHGEF16 {ECO:0000313|EMBL:SPT35725.1}; Flags: Fragment;+++[B0QZD3_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 16 {ECO:0000313|Ensembl:ENSP00000411936}; Flags: Fragment;+++[B0QZD4_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 16 {ECO:0000313|Ensembl:ENSP00000390853}; Flags: Fragment;+++[B3KTS4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38665 fis, clone HLUNG2003378, highly similar to Rho guanine nucleotide exchange factor 16 {ECO:0000313|EMBL:BAG53186.1};+++[L8EAP0_HUMAN|Unreviewed]SubName: Full=Alternative protein ARHGEF16 {ECO:0000313|EMBL:CCQ43438.1};"]
[27238,"'GPKOW'",245,276,281,267.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","G-patch domain and KOW motifs","[GPKOW_HUMAN|Reviewed]RecName: Full=G-patch domain and KOW motifs-containing protein; AltName: Full=G-patch domain-containing protein 5; AltName: Full=Protein MOS2 homolog; AltName: Full=Protein T54;"]
[27257,"'LSM1'",267,266,283,272,"03018///RNA degradation",null,"M00397///Lsm 1-7 complex",null,"GO:1990726///Lsm1-7-Pat1 complex+++GO:1990124///messenger ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005845///mRNA cap binding complex+++GO:0030425///dendrite+++GO:0000932///P-body+++GO:0043025///neuronal cell body+++GO:0030424///axon+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0036002///pre-mRNA binding","GO:0006397///mRNA processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0045665///negative regulation of neuron differentiation+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0019827///stem cell population maintenance+++GO:0071044///histone mRNA catabolic process+++GO:0016070///RNA metabolic process+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0008380///RNA splicing","LSM1 homolog, mRNA degradation associated","[LSM1_HUMAN|Reviewed]RecName: Full=U6 snRNA-associated Sm-like protein LSm1; AltName: Full=Cancer-associated Sm-like; AltName: Full=Small nuclear ribonuclear CaSm;+++[A0A0S2Z590_HUMAN|Unreviewed]RecName: Full=U6 snRNA-associated Sm-like protein LSm1 {ECO:0000256|RuleBase:RU365047}; Flags: Fragment;+++[E5RH18_HUMAN|Unreviewed]SubName: Full=LSM1-like protein U6 small nuclear RNA associated isoform 3 {ECO:0000313|EMBL:ALQ34065.1}; SubName: Full=U6 snRNA-associated Sm-like protein LSm1 {ECO:0000313|Ensembl:ENSP00000430021};+++[E5RJ47_HUMAN|Unreviewed]SubName: Full=U6 snRNA-associated Sm-like protein LSm1 {ECO:0000313|Ensembl:ENSP00000428307};"]
[2730,"'GCLM'",247,211,184,214,"00270///Cysteine and methionine metabolism+++04216///Ferroptosis+++01100///Metabolic pathways+++00480///Glutathione metabolism",null,"M00118///Glutathione biosynthesis, glutamate => glutathione","R00894///L-glutamate:L-cysteine gamma-ligase (ADP-forming)   ATP + L-Glutamate + L-Cysteine <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-cysteine+++R10993///L-glutamate:2-aminobutanoate gamma-ligase (ADP-forming)   ATP + L-Glutamate + (S)-2-Aminobutanoate <=> ADP + Orthophosphate + gamma-L-Glutamyl-L-2-aminobutyrate","GO:0017109///glutamate-cysteine ligase complex+++GO:0005829///cytosol","GO:0030234///enzyme regulator activity+++GO:0016874///ligase activity+++GO:0004357///glutamate-cysteine ligase activity+++GO:0035226///glutamate-cysteine ligase catalytic subunit binding+++GO:0046982///protein heterodimerization activity","GO:0042493///response to drug+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0006534///cysteine metabolic process+++GO:0051900///regulation of mitochondrial depolarization+++GO:0007584///response to nutrient+++GO:0006536///glutamate metabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0035733///hepatic stellate cell activation+++GO:0035229///positive regulation of glutamate-cysteine ligase activity+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0014823///response to activity+++GO:0006750///glutathione biosynthetic process+++GO:0035729///cellular response to hepatocyte growth factor stimulus+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0051409///response to nitrosative stress+++GO:0006749///glutathione metabolic process+++GO:0071333///cellular response to glucose stimulus+++GO:0097069///cellular response to thyroxine stimulus+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0050880///regulation of blood vessel size+++GO:0071372///cellular response to follicle-stimulating hormone stimulus+++GO:0044752///response to human chorionic gonadotropin+++GO:0008637///apoptotic mitochondrial changes","glutamate-cysteine ligase modifier subunit","[GSH0_HUMAN|Reviewed]RecName: Full=Glutamate--cysteine ligase regulatory subunit; AltName: Full=GCS light chain; AltName: Full=Gamma-ECS regulatory subunit; AltName: Full=Gamma-glutamylcysteine synthetase regulatory subunit; AltName: Full=Glutamate--cysteine ligase modifier subunit;+++[D3DT44_HUMAN|Unreviewed]SubName: Full=Glutamate-cysteine ligase, modifier subunit, isoform CRA_a {ECO:0000313|EMBL:EAW73062.1};"]
[27328,"'PCDH11X'",16.9,22.83,21.38,20.37,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0005509///calcium ion binding","GO:0010923///negative regulation of phosphatase activity+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","protocadherin 11 X-linked","[PC11X_HUMAN|Reviewed]RecName: Full=Protocadherin-11 X-linked; Short=Protocadherin-11; AltName: Full=Protocadherin on the X chromosome; Short=PCDH-X; AltName: Full=Protocadherin-S; Flags: Precursor;+++[Q9P2X4_HUMAN|Unreviewed]SubName: Full=Protocadherin-Xb {ECO:0000313|EMBL:BAA90766.1}; Flags: Fragment;"]
[27348,"'TOR1B'",481,607,633,573.666666666667,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0031965///nuclear membrane","GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:0071763///nuclear membrane organization+++GO:0006986///response to unfolded protein+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0051260///protein homooligomerization+++GO:0007029///endoplasmic reticulum organization","torsin family 1 member B","[TOR1B_HUMAN|Reviewed]RecName: Full=Torsin-1B; AltName: Full=Torsin ATPase-1B; EC=3.6.4.-; AltName: Full=Torsin family 1 member B; Flags: Precursor;+++[H0Y7C8_HUMAN|Unreviewed]SubName: Full=Torsin-1B {ECO:0000313|Ensembl:ENSP00000411912}; Flags: Fragment;+++[Q9BR69_HUMAN|Unreviewed]SubName: Full=TOR1B protein {ECO:0000313|EMBL:AAH06480.1};"]
[27430,"'MAT2B'",335,312,259,302,"01110///Biosynthesis of secondary metabolites+++00270///Cysteine and methionine metabolism+++01230///Biosynthesis of amino acids+++01100///Metabolic pathways","H00184///Hypermethioninemia","M00035///Methionine degradation+++M00609///Cysteine biosynthesis, methionine => cysteine+++M00368///Ethylene biosynthesis, methionine => ethylene+++M00034///Methionine salvage pathway","R00177///ATP:L-methionine S-adenosyltransferase   Orthophosphate + Diphosphate + S-Adenosyl-L-methionine <=> ATP + L-Methionine + H2O+++R04771///ATP:L-selenomethione S-adenosyltransferase   ATP + L-Selenomethionine + H2O <=> Orthophosphate + Diphosphate + Se-Adenosylselenomethionine","GO:0048269///methionine adenosyltransferase complex+++GO:0005634///nucleus+++GO:0005622///intracellular+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0048270///methionine adenosyltransferase regulator activity+++GO:0019899///enzyme binding","GO:0050790///regulation of catalytic activity+++GO:0006730///one-carbon metabolic process+++GO:0006556///S-adenosylmethionine biosynthetic process","methionine adenosyltransferase 2B","[MAT2B_HUMAN|Reviewed]RecName: Full=Methionine adenosyltransferase 2 subunit beta; AltName: Full=Methionine adenosyltransferase II beta; Short=MAT II beta; AltName: Full=Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase;+++[A0A140VJP2_HUMAN|Unreviewed]RecName: Full=Methionine adenosyltransferase 2 subunit beta {ECO:0000256|RuleBase:RU364081}; AltName: Full=Methionine adenosyltransferase II beta {ECO:0000256|RuleBase:RU364081};+++[E5RJR3_HUMAN|Unreviewed]RecName: Full=Methionine adenosyltransferase 2 subunit beta {ECO:0000256|RuleBase:RU364081}; AltName: Full=Methionine adenosyltransferase II beta {ECO:0000256|RuleBase:RU364081};+++[H7C0X7_HUMAN|Unreviewed]RecName: Full=Methionine adenosyltransferase 2 subunit beta {ECO:0000256|RuleBase:RU364081}; AltName: Full=Methionine adenosyltransferase II beta {ECO:0000256|RuleBase:RU364081}; Flags: Fragment;"]
[2769,"'GNA15'",0,0,1,0.333333333333333,"04926///Relaxin signaling pathway+++04020///Calcium signaling pathway+++05146///Amoebiasis+++05142///Chagas disease (American trypanosomiasis)",{"$nulls":3},"GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane","GO:0000166///nucleotide binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0019001///guanyl nucleotide binding+++GO:0046872///metal ion binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0001664///G protein-coupled receptor binding","GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0007202///activation of phospholipase C activity+++GO:0030168///platelet activation+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007207///phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway","G protein subunit alpha 15","[GNA15_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein subunit alpha-15; Short=G alpha-15; Short=G-protein subunit alpha-15; AltName: Full=Epididymis tissue protein Li 17E; AltName: Full=Guanine nucleotide-binding protein subunit alpha-16; Short=G alpha-16; Short=G-protein subunit alpha-16;+++[K7EP74_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein subunit alpha-15 {ECO:0000313|Ensembl:ENSP00000467256};"]
[2783,"'GNB2'",2345,2596,2817,2586,"04062///Chemokine signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04725///Cholinergic synapse+++04723///Retrograde endocannabinoid signaling+++04014///Ras signaling pathway+++04724///Glutamatergic synapse+++05032///Morphine addiction+++04727///GABAergic synapse+++04151///PI3K-Akt signaling pathway+++04713///Circadian entrainment+++05034///Alcoholism+++04728///Dopaminergic synapse+++04926///Relaxin signaling pathway+++05200///Pathways in cancer+++05163///Human cytomegalovirus infection+++04726///Serotonergic synapse+++04371///Apelin signaling pathway",{"$nulls":3},"GO:0044297///cell body+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0043209///myelin sheath+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0031982///vesicle+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0005765///lysosomal membrane+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0005246///calcium channel regulator activity+++GO:0003924///GTPase activity+++GO:0051020///GTPase binding+++GO:0044877///protein-containing complex binding","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006457///protein folding","G protein subunit beta 2","[GBB2_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2; AltName: Full=G protein subunit beta-2; AltName: Full=Transducin beta chain 2;+++[C9JIS1_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 {ECO:0000313|Ensembl:ENSP00000390077}; Flags: Fragment;+++[C9JXA5_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 {ECO:0000313|Ensembl:ENSP00000399904}; Flags: Fragment;+++[C9JZN1_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 {ECO:0000313|Ensembl:ENSP00000413219}; Flags: Fragment;+++[E7EP32_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 {ECO:0000313|Ensembl:ENSP00000389391};+++[Q6FHM2_HUMAN|Unreviewed]SubName: Full=GNB2 protein {ECO:0000313|EMBL:CAG46530.1}; SubName: Full=Guanine nucleotide binding protein (G protein), beta polypeptide 2, isoform CRA_a {ECO:0000313|EMBL:EAW76499.1}; SubName: Full=cDNA FLJ77321, highly similar to Homo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2 (GNB2), mRNA {ECO:0000313|EMBL:BAF84281.1};"]
[2806,"'GOT2'",6833,3949,5180,5320.66666666667,"01200///Carbon metabolism+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++01210///2-Oxocarboxylic acid metabolism+++00400///Phenylalanine, tyrosine and tryptophan biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++00350///Tyrosine metabolism+++00220///Arginine biosynthesis+++00960///Tropane, piperidine and pyridine alkaloid biosynthesis+++00950///Isoquinoline alkaloid biosynthesis+++00360///Phenylalanine metabolism+++01130///Biosynthesis of antibiotics+++00270///Cysteine and methionine metabolism+++01230///Biosynthesis of amino acids+++04975///Fat digestion and absorption+++00710///Carbon fixation in photosynthetic organisms+++00330///Arginine and proline metabolism",null,"M00171///C4-dicarboxylic acid cycle, NAD - malic enzyme type+++M00170///C4-dicarboxylic acid cycle, phosphoenolpyruvate carboxykinase type","R05052///L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase   L-erythro-4-Hydroxyglutamate + 2-Oxoglutarate <=> (4R)-4-Hydroxy-2-oxoglutarate + L-Glutamate+++R02619///3-sulfino-L-alanine:2-oxoglutarate aminotransferase   3-Sulfino-L-alanine + 2-Oxoglutarate <=> 3-Sulfinylpyruvate + L-Glutamate+++R02433///L-cysteate:2-oxoglutarate aminotransferase   L-Cysteate + 2-Oxoglutarate <=> 3-Sulfopyruvate + L-Glutamate+++R00734///L-tyrosine:2-oxoglutarate aminotransferase   L-Tyrosine + 2-Oxoglutarate <=> 3-(4-Hydroxyphenyl)pyruvate + L-Glutamate+++R00896///L-cysteine:2-oxoglutarate aminotransferase   L-Cysteine + 2-Oxoglutarate <=> Mercaptopyruvate + Glutamate+++R00355///L-Aspartate:2-oxoglutarate aminotransferase   L-Aspartate + 2-Oxoglutarate <=> Oxaloacetate + L-Glutamate+++R00694///L-Phenylalanine:2-oxoglutarate aminotransferase   L-Phenylalanine + 2-Oxoglutarate <=> Phenylpyruvate + L-Glutamate","GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0043204///perikaryon+++GO:0005739///mitochondrion+++GO:0009986///cell surface+++GO:0030315///T-tubule+++GO:0005759///mitochondrial matrix+++GO:0042383///sarcolemma+++GO:0005743///mitochondrial inner membrane","GO:0008483///transaminase activity+++GO:0016740///transferase activity+++GO:0004069///L-aspartate:2-oxoglutarate aminotransferase activity+++GO:0005543///phospholipid binding+++GO:0016212///kynurenine-oxoglutarate transaminase activity+++GO:0003824///catalytic activity+++GO:0003723///RNA binding+++GO:0031406///carboxylic acid binding+++GO:0030170///pyridoxal phosphate binding+++GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0047578///4-hydroxyglutamate transaminase activity+++GO:0016597///amino acid binding","GO:0043278///response to morphine+++GO:0009058///biosynthetic process+++GO:0015908///fatty acid transport+++GO:0006533///aspartate catabolic process+++GO:0007565///female pregnancy+++GO:0032868///response to insulin+++GO:0046487///glyoxylate metabolic process+++GO:0006536///glutamate metabolic process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0014850///response to muscle activity+++GO:0019551///glutamate catabolic process to 2-oxoglutarate+++GO:0006531///aspartate metabolic process+++GO:0043648///dicarboxylic acid metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0019550///glutamate catabolic process to aspartate+++GO:0045471///response to ethanol+++GO:0006107///oxaloacetate metabolic process+++GO:0019470///4-hydroxyproline catabolic process+++GO:0006532///aspartate biosynthetic process+++GO:0097052///L-kynurenine metabolic process+++GO:0007595///lactation+++GO:0006869///lipid transport+++GO:0006094///gluconeogenesis+++GO:0006520///cellular amino acid metabolic process","glutamic-oxaloacetic transaminase 2","[AATM_HUMAN|Reviewed]RecName: Full=Aspartate aminotransferase, mitochondrial; Short=mAspAT; EC=2.6.1.1 {ECO:0000269|PubMed:26902786}; EC=2.6.1.7; AltName: Full=Fatty acid-binding protein; Short=FABP-1; AltName: Full=Glutamate oxaloacetate transaminase 2; AltName: Full=Kynurenine aminotransferase 4; AltName: Full=Kynurenine aminotransferase IV; AltName: Full=Kynurenine--oxoglutarate transaminase 4; AltName: Full=Kynurenine--oxoglutarate transaminase IV; AltName: Full=Plasma membrane-associated fatty acid-binding protein; Short=FABPpm; AltName: Full=Transaminase A; Flags: Precursor;+++[A0A024R6W0_HUMAN|Unreviewed]RecName: Full=Aspartate aminotransferase {ECO:0000256|RuleBase:RU000480}; EC=2.6.1.1 {ECO:0000256|RuleBase:RU000480};+++[H3BRE7_HUMAN|Unreviewed]SubName: Full=Aspartate aminotransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456205};"]
[28227,"'PPP2R3B'",307,338,396,347,"04152///AMPK signaling pathway+++03015///mRNA surveillance pathway+++04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++04071///Sphingolipid signaling pathway",{"$nulls":3},"GO:0000159///protein phosphatase type 2A complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0019888///protein phosphatase regulator activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0007050///cell cycle arrest+++GO:0006470///protein dephosphorylation","protein phosphatase 2 regulatory subunit B''beta","[P2R3B_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta; AltName: Full=PP2A subunit B isoform PR48; AltName: Full=Protein phosphatase 2A 48 kDa regulatory subunit;+++[A0A0G2JN52_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta {ECO:0000313|Ensembl:ENSP00000480675};+++[A0A0G2JNR6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta {ECO:0000313|Ensembl:ENSP00000481962};+++[C9JMU6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta {ECO:0000313|Ensembl:ENSP00000371038}; Flags: Fragment;+++[Q96FD8_HUMAN|Unreviewed]SubName: Full=PPP2R3B protein {ECO:0000313|EMBL:AAH11180.2}; Flags: Fragment;"]
[282996,"'RBM20'",35,35,20,30,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0007507///heart development+++GO:0006397///mRNA processing+++GO:0043484///regulation of RNA splicing+++GO:0008380///RNA splicing+++GO:0033120///positive regulation of RNA splicing","RNA binding motif protein 20","[RBM20_HUMAN|Reviewed]RecName: Full=RNA-binding protein 20; AltName: Full=RNA-binding motif protein 20;"]
[283149,"'BCL9L'",5633,6254,5628,5838.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:1990907///beta-catenin-TCF complex+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity+++GO:0008013///beta-catenin binding","GO:0022604///regulation of cell morphogenesis+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0035019///somatic stem cell population maintenance+++GO:0035914///skeletal muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0060070///canonical Wnt signaling pathway+++GO:1904837///beta-catenin-TCF complex assembly","B cell CLL/lymphoma 9 like","[BCL9L_HUMAN|Reviewed]RecName: Full=B-cell CLL/lymphoma 9-like protein; Short=B-cell lymphoma 9-like protein; Short=BCL9-like protein; AltName: Full=Protein BCL9-2;+++[A0A087WZX0_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 9-like protein {ECO:0000313|Ensembl:ENSP00000482938};+++[E9PNR0_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 9-like protein {ECO:0000313|Ensembl:ENSP00000432804}; Flags: Fragment;"]
[283383,"'ADGRD1'",14,20,11,15,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor D1","[AGRD1_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor D1 {ECO:0000303|PubMed:25713288}; AltName: Full=G-protein coupled receptor 133; AltName: Full=G-protein coupled receptor PGR25; Flags: Precursor;+++[A0A087WYZ5_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor D1 {ECO:0000313|Ensembl:ENSP00000482235};+++[F5H7I3_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor D1 {ECO:0000313|Ensembl:ENSP00000442501}; Flags: Fragment;+++[H0Y2U9_HUMAN|Unreviewed]SubName: Full=Adhesion G-protein-coupled receptor D1 {ECO:0000313|Ensembl:ENSP00000334127};+++[Q9NSM3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434B1272 {ECO:0000313|EMBL:CAB82385.1}; Flags: Fragment;"]
[283459,"'GATC'",458,445.02,396,433.006666666667,"01100///Metabolic pathways+++00970///Aminoacyl-tRNA biosynthesis",null,null,"R03905///Glu-tRNA(Gln):L-glutamine amido-ligase(ADP-forming)   Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O+++R04212///Asp-tRNA(Asn):L-glutamine amido-ligase (ADP-forming)   L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O","GO:0005739///mitochondrion+++GO:0030956///glutamyl-tRNA(Gln) amidotransferase complex","GO:0000166///nucleotide binding+++GO:0016884///carbon-nitrogen ligase activity, with glutamine as amido-N-donor+++GO:0016874///ligase activity+++GO:0005515///protein binding+++GO:0050567///glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity+++GO:0005524///ATP binding","GO:0006450///regulation of translational fidelity+++GO:0032543///mitochondrial translation+++GO:0006412///translation+++GO:0070681///glutaminyl-tRNAGln biosynthesis via transamidation","glutamyl-tRNA amidotransferase subunit C","[GATC_HUMAN|Reviewed]RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03149}; Short=Glu-AdT subunit C {ECO:0000255|HAMAP-Rule:MF_03149}; EC=6.3.5.- {ECO:0000255|HAMAP-Rule:MF_03149}; AltName: Full=Protein 15E1.2;+++[F8VRU3_HUMAN|Unreviewed]SubName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial {ECO:0000313|Ensembl:ENSP00000448397};+++[J3KMY1_HUMAN|Unreviewed]SubName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial {ECO:0000313|Ensembl:ENSP00000229384}; Flags: Fragment;"]
[283848,"'CES4A'",73,66,83,74,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0004771///sterol esterase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0004806///triglyceride lipase activity+++GO:0016787///hydrolase activity","GO:0016042///lipid catabolic process","carboxylesterase 4A","[EST4A_HUMAN|Reviewed]RecName: Full=Carboxylesterase 4A; EC=3.1.1.-; Flags: Precursor;+++[A0A0C4DGH1_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[F5GZV6_HUMAN|Unreviewed]SubName: Full=Carboxylesterase 4A {ECO:0000313|Ensembl:ENSP00000444182};+++[I3L191_HUMAN|Unreviewed]SubName: Full=Carboxylesterase 4A {ECO:0000313|Ensembl:ENSP00000458664}; Flags: Fragment;+++[Q6P2E5_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;"]
[284001,"'CCDC57'",351.46,365.32,418,378.26,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding",null,"coiled-coil domain containing 57","[CCD57_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 57;+++[E9PDF5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 57 {ECO:0000313|Ensembl:ENSP00000376157};+++[H7BYI8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 57 {ECO:0000313|Ensembl:ENSP00000376156}; Flags: Fragment;+++[J3KRQ8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 57 {ECO:0000313|Ensembl:ENSP00000462121}; Flags: Fragment;+++[J3KSU5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 57 {ECO:0000313|Ensembl:ENSP00000462653}; Flags: Fragment;+++[J3QQX7_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 57 {ECO:0000313|Ensembl:ENSP00000463946}; Flags: Fragment;+++[K7N7D6_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 57 {ECO:0000313|Ensembl:ENSP00000408124}; Flags: Fragment;"]
[284040,"'CDRT4'",46.14,86.37,58.15,63.5533333333333,{"$nulls":5},"GO:0005515///protein binding",null,"CMT1A duplicated region transcript 4","[CDRT4_HUMAN|Reviewed]RecName: Full=CMT1A duplicated region transcript 4 protein;+++[D3DTT2_HUMAN|Unreviewed]SubName: Full=CMT1A duplicated region transcript 4 protein {ECO:0000313|Ensembl:ENSP00000482523}; SubName: Full=HCG1820468, isoform CRA_a {ECO:0000313|EMBL:EAW89941.1};+++[G3V5I9_HUMAN|Unreviewed]SubName: Full=CMT1A duplicated region transcript 4 protein {ECO:0000313|Ensembl:ENSP00000452374}; Flags: Fragment;"]
[284119,"'CAVIN1'",11964,13661,13668,13097.6666666667,null,"H00419///Congenital generalized lipodystrophy (CGL)",null,null,"GO:0005901///caveola+++GO:0005783///endoplasmic reticulum+++GO:0045121///membrane raft+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0019843///rRNA binding+++GO:0003723///RNA binding+++GO:0042134///rRNA primary transcript binding","GO:0006353///DNA-templated transcription, termination+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:2000147///positive regulation of cell motility+++GO:0009303///rRNA transcription+++GO:0006363///termination of RNA polymerase I transcription","caveolae associated protein 1","[CAVN1_HUMAN|Reviewed]RecName: Full=Caveolae-associated protein 1 {ECO:0000312|HGNC:HGNC:9688}; AltName: Full=Cavin-1; AltName: Full=Polymerase I and transcript release factor;"]
[284339,"'TMEM145'",22,8,30,20,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019236///response to pheromone","transmembrane protein 145","[TM145_HUMAN|Reviewed]RecName: Full=Transmembrane protein 145;+++[M0QZK1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 145 {ECO:0000313|Ensembl:ENSP00000470602}; Flags: Fragment;+++[M0QZX2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 145 {ECO:0000313|Ensembl:ENSP00000470827};"]
[284391,"'ZNF844'",119.63,118.01,142.69,126.776666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 844","[ZN844_HUMAN|Reviewed]RecName: Full=Zinc finger protein 844;+++[B4DSG8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58103, moderately similar to Zinc finger protein 433 {ECO:0000313|EMBL:BAG61630.1};+++[F8VS19_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 844 {ECO:0000313|Ensembl:ENSP00000448588}; Flags: Fragment;+++[F8WE48_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 844 {ECO:0000313|Ensembl:ENSP00000402097};"]
[284612,"'SYPL2'",66,78,73,72.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane",null,"GO:0006874///cellular calcium ion homeostasis+++GO:0021762///substantia nigra development","synaptophysin like 2","[SYPL2_HUMAN|Reviewed]RecName: Full=Synaptophysin-like protein 2;+++[B4DYR7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57854, highly similar to Synaptophysin-like protein 2 {ECO:0000313|EMBL:BAG63829.1};+++[Q14DL7_HUMAN|Unreviewed]SubName: Full=SYPL2 protein {ECO:0000313|EMBL:AAI13104.1};"]
[2848,"'GPR25'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","G protein-coupled receptor 25","[GPR25_HUMAN|Reviewed]RecName: Full=Probable G-protein coupled receptor 25;"]
[285190,"'RGPD4'",8.56,9.09,5.22,7.62333333333333,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005813///centrosome+++GO:0005643///nuclear pore+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005096///GTPase activator activity+++GO:0008536///Ran GTPase binding","GO:0006607///NLS-bearing protein import into nucleus+++GO:0046907///intracellular transport+++GO:0043547///positive regulation of GTPase activity","RANBP2-like and GRIP domain containing 4","[RGPD4_HUMAN|Reviewed]RecName: Full=RanBP2-like and GRIP domain-containing protein 4;"]
[285346,"'ZNF852'",17,19,17,17.6666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 852","[ZN852_HUMAN|Reviewed]RecName: Full=Zinc finger protein 852;"]
[285527,"'FRYL'",616,653,336,535,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005938///cell cortex",null,"GO:0000902///cell morphogenesis+++GO:0031175///neuron projection development","FRY like transcription coactivator","[FRYL_HUMAN|Reviewed]RecName: Full=Protein furry homolog-like; AltName: Full=ALL1-fused gene from chromosome 4p12 protein;+++[A0A286YEZ9_HUMAN|Unreviewed]SubName: Full=Protein furry homolog-like {ECO:0000313|Ensembl:ENSP00000493144}; Flags: Fragment;+++[A0A2C9F2R7_HUMAN|Unreviewed]SubName: Full=Protein furry homolog-like {ECO:0000313|Ensembl:ENSP00000422408}; Flags: Fragment;+++[B3KXG5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45375 fis, clone BRHIP3019824 {ECO:0000313|EMBL:BAG54477.1};+++[D6R9B9_HUMAN|Unreviewed]SubName: Full=Protein furry homolog-like {ECO:0000313|Ensembl:ENSP00000422988}; Flags: Fragment;+++[D6RJI4_HUMAN|Unreviewed]SubName: Full=Protein furry homolog-like {ECO:0000313|Ensembl:ENSP00000425592};+++[F2Z2S2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog-like {ECO:0000313|Ensembl:ENSP00000421584};+++[H0Y9X0_HUMAN|Unreviewed]SubName: Full=Protein furry homolog-like {ECO:0000313|Ensembl:ENSP00000425344}; Flags: Fragment;+++[Q6ZR29_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46702 fis, clone TRACH3014183 {ECO:0000313|EMBL:BAC87492.1};"]
[285676,"'ZNF454'",77.91,74.82,69.09,73.94,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 454","[ZN454_HUMAN|Reviewed]RecName: Full=Zinc finger protein 454;"]
[285989,"'ZNF789'",163.85,158,139.26,153.703333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 789","[ZN789_HUMAN|Reviewed]RecName: Full=Zinc finger protein 789;+++[C9J3R7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000417227};+++[C9J487_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000405206};+++[C9JUE3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000419500};+++[F8WEN0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 789 {ECO:0000313|Ensembl:ENSP00000401255};"]
[286223,"'C9orf47'",0,0,1,0.333333333333333,"04080///Neuroactive ligand-receptor interaction+++04071///Sphingolipid signaling pathway",{"$nulls":3},"GO:0005576///extracellular region","GO:0008289///lipid binding+++GO:0005178///integrin binding+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0001816///cytokine production+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0008284///positive regulation of cell proliferation+++GO:1903141///negative regulation of establishment of endothelial barrier+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0032651///regulation of interleukin-1 beta production+++GO:0009653///anatomical structure morphogenesis+++GO:0006954///inflammatory response+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway","chromosome 9 open reading frame 47","[CI047_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C9orf47; Flags: Precursor;+++[Q5SQD6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C9orf47 {ECO:0000313|Ensembl:ENSP00000365010};"]
[286676,"'ILDR1'",15,2,16,11,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0061689///tricellular tight junction+++GO:0005829///cytosol","GO:0070506///high-density lipoprotein particle receptor activity+++GO:0042802///identical protein binding","GO:0006898///receptor-mediated endocytosis+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0090277///positive regulation of peptide hormone secretion+++GO:0051260///protein homooligomerization","immunoglobulin like domain containing receptor 1","[ILDR1_HUMAN|Reviewed]RecName: Full=Immunoglobulin-like domain-containing receptor 1; Flags: Precursor;"]
[2882,"'GPX7'",944,880,864,896,"00590///Arachidonic acid metabolism+++00480///Glutathione metabolism+++04918///Thyroid hormone synthesis","H00668///Anemia due to disorders of glutathione metabolism",null,"R07035///Glutathione: 15-HPETE oxidoreductase   2 Glutathione + 15(S)-HPETE <=> Glutathione disulfide + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + H2O+++R07034///Glutathione: 5-HPETE oxidoreductase   2 Glutathione + 5(S)-HPETE <=> Glutathione disulfide + 5(S)-HETE + H2O+++R00274///glutathione:hydrogen-peroxide oxidoreductase   Hydrogen peroxide + 2 Glutathione <=> Glutathione disulfide + 2 H2O","GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0004096///catalase activity+++GO:0004602///glutathione peroxidase activity+++GO:0005515///protein binding+++GO:0004601///peroxidase activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0098869///cellular oxidant detoxification+++GO:0006979///response to oxidative stress+++GO:0034599///cellular response to oxidative stress","glutathione peroxidase 7","[GPX7_HUMAN|Reviewed]RecName: Full=Glutathione peroxidase 7; Short=GPx-7; Short=GSHPx-7; EC=1.11.1.9; AltName: Full=CL683; Flags: Precursor;"]
[28954,"'REM1'",3,0,0,1,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005516///calmodulin binding","GO:0007165///signal transduction+++GO:1901842///negative regulation of high voltage-gated calcium channel activity","RRAD and GEM like GTPase 1","[REM1_HUMAN|Reviewed]RecName: Full=GTP-binding protein REM 1; AltName: Full=GTPase-regulating endothelial cell sprouting; AltName: Full=Rad and Gem-like GTP-binding protein 1;"]
[28974,"'C19orf53'",1878,1949,2130,1985.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus",null,null,"chromosome 19 open reading frame 53","[L10K_HUMAN|Reviewed]RecName: Full=Leydig cell tumor 10 kDa protein homolog;+++[A0A0A0MQS3_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000221576}; Flags: Fragment;+++[K7EIU1_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000464891}; Flags: Fragment;+++[K7EN09_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000466736}; Flags: Fragment;+++[K7ESE5_HUMAN|Unreviewed]SubName: Full=Leydig cell tumor 10 kDa protein homolog {ECO:0000313|Ensembl:ENSP00000468676};"]
[2899,"'GRIK3'",74,43,39,52,"04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse",{"$nulls":3},"GO:0098978///glutamatergic synapse+++GO:0043204///perikaryon+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0032839///dendrite cytoplasm+++GO:0030425///dendrite+++GO:0032983///kainate selective glutamate receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042734///presynaptic membrane+++GO:0043195///terminal bouton+++GO:0030424///axon+++GO:0030054///cell junction+++GO:0045202///synapse","GO:0004970///ionotropic glutamate receptor activity+++GO:0005216///ion channel activity+++GO:0001664///G protein-coupled receptor binding+++GO:0099507///ligand-gated ion channel activity involved in regulation of presynaptic membrane potential+++GO:0008066///glutamate receptor activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0001640///adenylate cyclase inhibiting G protein-coupled glutamate receptor activity+++GO:0038023///signaling receptor activity","GO:0034220///ion transmembrane transport+++GO:0006811///ion transport+++GO:0007196///adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway+++GO:0007215///glutamate receptor signaling pathway+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0099505///regulation of presynaptic membrane potential+++GO:0050804///modulation of chemical synaptic transmission+++GO:0042391///regulation of membrane potential+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0051967///negative regulation of synaptic transmission, glutamatergic","glutamate ionotropic receptor kainate type subunit 3","[GRIK3_HUMAN|Reviewed]RecName: Full=Glutamate receptor ionotropic, kainate 3; Short=GluK3; AltName: Full=Excitatory amino acid receptor 5; Short=EAA5; AltName: Full=Glutamate receptor 7; Short=GluR-7; Short=GluR7; Flags: Precursor;+++[Q96QG5_HUMAN|Unreviewed]SubName: Full=Glutamate receptor 7 {ECO:0000313|EMBL:CAC44965.1};+++[Q96SC0_HUMAN|Unreviewed]SubName: Full=Glutamate receptor 7 {ECO:0000313|EMBL:CAC40657.1}; Flags: Fragment;+++[Q96SC1_HUMAN|Unreviewed]SubName: Full=Glutamate receptor 7 {ECO:0000313|EMBL:CAC40656.1}; Flags: Fragment;+++[Q96SC2_HUMAN|Unreviewed]SubName: Full=Glutamate receptor 7 {ECO:0000313|EMBL:CAC40655.1}; Flags: Fragment;"]
[28996,"'HIPK2'",2597,2217,1776,2196.66666666667,"04218///Cellular senescence",{"$nulls":3},"GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0046332///SMAD binding+++GO:0046790///virion binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003714///transcription corepressor activity+++GO:0016301///kinase activity+++GO:0003713///transcription coactivator activity+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0018105///peptidyl-serine phosphorylation+++GO:0001654///eye development+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0007224///smoothened signaling pathway+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030218///erythrocyte differentiation+++GO:0007628///adult walking behavior+++GO:0010842///retina layer formation+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0045766///positive regulation of angiogenesis+++GO:0030578///PML body organization+++GO:0006468///protein phosphorylation+++GO:0051726///regulation of cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060395///SMAD protein signal transduction+++GO:0060235///lens induction in camera-type eye+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0006915///apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0050882///voluntary musculoskeletal movement+++GO:0008344///adult locomotory behavior+++GO:0046330///positive regulation of JNK cascade+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0032092///positive regulation of protein binding+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0071456///cellular response to hypoxia+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0061072///iris morphogenesis+++GO:0043388///positive regulation of DNA binding+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030182///neuron differentiation+++GO:0009952///anterior/posterior pattern specification","homeodomain interacting protein kinase 2","[HIPK2_HUMAN|Reviewed]RecName: Full=Homeodomain-interacting protein kinase 2; Short=hHIPk2; EC=2.7.11.1;+++[A4D1R9_HUMAN|Unreviewed]SubName: Full=Homeodomain interacting protein kinase 2 {ECO:0000313|EMBL:EAL24035.1};+++[H7BXX9_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 2 {ECO:0000313|Ensembl:ENSP00000343108};+++[L8ECJ8_HUMAN|Unreviewed]SubName: Full=Alternative protein HIPK2 {ECO:0000313|EMBL:CCQ43692.1};"]
[29079,"'MED4'",251,206,238,231.666666666667,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0070847///core mediator complex+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0038023///signaling receptor activity+++GO:0042809///vitamin D receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0005515///protein binding+++GO:0046966///thyroid hormone receptor binding+++GO:0003712///transcription coregulator activity","GO:0030521///androgen receptor signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter","mediator complex subunit 4","[MED4_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 4; AltName: Full=Activator-recruited cofactor 36 kDa component; Short=ARC36; AltName: Full=Mediator complex subunit 4; AltName: Full=TRAP/SMCC/PC2 subunit p36 subunit; AltName: Full=Vitamin D3 receptor-interacting protein complex 36 kDa component; Short=DRIP36;+++[A0A024RDY7_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 4 {ECO:0000256|RuleBase:RU364141}; AltName: Full=Mediator complex subunit 4 {ECO:0000256|RuleBase:RU364141};+++[A0A087X0U0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 4 {ECO:0000313|Ensembl:ENSP00000483651}; Flags: Fragment;+++[Q5T911_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 4 {ECO:0000256|RuleBase:RU364141}; AltName: Full=Mediator complex subunit 4 {ECO:0000256|RuleBase:RU364141}; Flags: Fragment;+++[U4PSC4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 4 {ECO:0000256|RuleBase:RU364141}; AltName: Full=Mediator complex subunit 4 {ECO:0000256|RuleBase:RU364141}; Flags: Fragment;"]
[29085,"'PHPT1'",1199,1522,1632,1451,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0044325///ion channel binding+++GO:0019855///calcium channel inhibitor activity+++GO:0005515///protein binding+++GO:0101006///protein histidine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity","GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:2000147///positive regulation of cell motility+++GO:0006470///protein dephosphorylation+++GO:0035971///peptidyl-histidine dephosphorylation+++GO:2000984///negative regulation of ATP citrate synthase activity+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:0051350///negative regulation of lyase activity","phosphohistidine phosphatase 1","[PHP14_HUMAN|Reviewed]RecName: Full=14 kDa phosphohistidine phosphatase {ECO:0000303|PubMed:12383260}; EC=3.9.1.3 {ECO:0000269|PubMed:19836471, ECO:0000269|PubMed:25574816}; AltName: Full=Phosphohistidine phosphatase 1 {ECO:0000303|PubMed:25574816}; Short=PHPT1 {ECO:0000303|PubMed:25574816}; AltName: Full=Protein histidine phosphatase {ECO:0000303|PubMed:19836471}; Short=PHP {ECO:0000303|PubMed:19836471}; AltName: Full=Protein janus-A homolog;+++[Q6FIE5_HUMAN|Unreviewed]SubName: Full=PHP14 protein {ECO:0000313|EMBL:CAG38512.1};+++[V9HWC4_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 132P {ECO:0000313|EMBL:ACJ13700.1}; SubName: Full=Phosphohistidine phosphatase 1, isoform CRA_a {ECO:0000313|EMBL:EAW88291.1};"]
[29102,"'DROSHA'",1473,1459,1180,1370.66666666667,"05205///Proteoglycans in cancer+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0014069///postsynaptic density+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0070877///microprocessor complex+++GO:0005730///nucleolus","GO:0001530///lipopolysaccharide binding+++GO:0003723///RNA binding+++GO:0070878///primary miRNA binding+++GO:0042803///protein homodimerization activity+++GO:0004521///endoribonuclease activity+++GO:0046332///SMAD binding+++GO:0070412///R-SMAD binding+++GO:0017151///DEAD/H-box RNA helicase binding+++GO:0004525///ribonuclease III activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0004518///nuclease activity+++GO:0016787///hydrolase activity+++GO:0003725///double-stranded RNA binding+++GO:0046872///metal ion binding","GO:0010468///regulation of gene expression+++GO:0050829///defense response to Gram-negative bacterium+++GO:0006396///RNA processing+++GO:0010628///positive regulation of gene expression+++GO:2000628///regulation of miRNA metabolic process+++GO:0016075///rRNA catabolic process+++GO:0031054///pre-miRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0030422///production of siRNA involved in RNA interference+++GO:0010586///miRNA metabolic process+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0050727///regulation of inflammatory response+++GO:0031047///gene silencing by RNA+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0050830///defense response to Gram-positive bacterium+++GO:0042254///ribosome biogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0031053///primary miRNA processing","drosha ribonuclease III","[RNC_HUMAN|Reviewed]RecName: Full=Ribonuclease 3; EC=3.1.26.3 {ECO:0000269|PubMed:15565168, ECO:0000269|PubMed:15574589, ECO:0000269|PubMed:26027739, ECO:0000269|PubMed:26748718}; AltName: Full=Protein Drosha {ECO:0000303|PubMed:14508493}; AltName: Full=Ribonuclease III; Short=RNase III; AltName: Full=p241;+++[A0A024RE13_HUMAN|Unreviewed]SubName: Full=Ribonuclease III, nuclear, isoform CRA_a {ECO:0000313|EMBL:EAX10768.1};+++[E5RHD1_HUMAN|Unreviewed]SubName: Full=Ribonuclease 3 {ECO:0000313|Ensembl:ENSP00000430921}; Flags: Fragment;+++[H0YB67_HUMAN|Unreviewed]SubName: Full=Ribonuclease 3 {ECO:0000313|Ensembl:ENSP00000428782}; Flags: Fragment;+++[H7C5U6_HUMAN|Unreviewed]SubName: Full=Ribonuclease 3 {ECO:0000313|Ensembl:ENSP00000422745}; Flags: Fragment;"]
[2915,"'GRM5'",3,5,5,4.33333333333333,"05016///Huntington's disease+++04540///Gap junction+++04724///Glutamatergic synapse+++04020///Calcium signaling pathway+++04072///Phospholipase D signaling pathway+++04723///Retrograde endocannabinoid signaling+++04080///Neuroactive ligand-receptor interaction+++04720///Long-term potentiation",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0043005///neuron projection+++GO:0098839///postsynaptic density membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0099583///neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration+++GO:1990782///protein tyrosine kinase binding+++GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0008066///glutamate receptor activity+++GO:0099530///G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential","GO:0007165///signal transduction+++GO:0050808///synapse organization+++GO:0001932///regulation of protein phosphorylation+++GO:0006448///regulation of translational elongation+++GO:1902938///regulation of intracellular calcium activated chloride channel activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:1904646///cellular response to amyloid-beta+++GO:0007268///chemical synaptic transmission+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0007611///learning or memory+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0006417///regulation of translation+++GO:0090647///modulation of age-related behavioral decline+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0099553///trans-synaptic signaling by endocannabinoid, modulating synaptic transmission+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0099170///postsynaptic modulation of chemical synaptic transmission+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0007206///phospholipase C-activating G protein-coupled glutamate receptor signaling pathway+++GO:0007612///learning+++GO:0050890///cognition+++GO:0007626///locomotory behavior","glutamate metabotropic receptor 5","[GRM5_HUMAN|Reviewed]RecName: Full=Metabotropic glutamate receptor 5; Short=mGluR5; Flags: Precursor;+++[A8K5P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75523, highly similar to Homo sapiens glutamate receptor, metabotropic 5 (GRM5), mRNA {ECO:0000313|EMBL:BAF84051.1}; Flags: Fragment;+++[A8MT20_HUMAN|Unreviewed]SubName: Full=Metabotropic glutamate receptor 5 {ECO:0000313|Ensembl:ENSP00000376972};+++[G8XUU6_HUMAN|Unreviewed]SubName: Full=Metabotropic glutamate receptor 5 variant F {ECO:0000313|EMBL:ACU31022.1};+++[G8XUU7_HUMAN|Unreviewed]SubName: Full=Metabotropic glutamate receptor 5 variant G {ECO:0000313|EMBL:ACU31023.1};+++[G8XUU8_HUMAN|Unreviewed]SubName: Full=Metabotropic glutamate receptor 5 variant H {ECO:0000313|EMBL:ACU31024.1};+++[H7C223_HUMAN|Unreviewed]SubName: Full=Metabotropic glutamate receptor 5 {ECO:0000313|Ensembl:ENSP00000403724}; Flags: Fragment;+++[K9J9K9_HUMAN|Unreviewed]SubName: Full=GRM5 variant 9 {ECO:0000313|EMBL:ACV89822.1};"]
[2925,"'GRPR'",18,2,15,11.6666666666667,"04080///Neuroactive ligand-receptor interaction+++04020///Calcium signaling pathway",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0004930///G protein-coupled receptor activity+++GO:0042923///neuropeptide binding+++GO:0008188///neuropeptide receptor activity+++GO:0008528///G protein-coupled peptide receptor activity","GO:0007165///signal transduction+++GO:0061744///motor behavior+++GO:0008283///cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035176///social behavior+++GO:0043207///response to external biotic stimulus+++GO:0036343///psychomotor behavior+++GO:0007611///learning or memory+++GO:0007218///neuropeptide signaling pathway","gastrin releasing peptide receptor","[GRPR_HUMAN|Reviewed]RecName: Full=Gastrin-releasing peptide receptor; Short=GRP-R; AltName: Full=GRP-preferring bombesin receptor;+++[X5D7H2_HUMAN|Unreviewed]SubName: Full=Gastrin-releasing peptide receptor isoform A {ECO:0000313|EMBL:AHW56495.1}; Flags: Fragment;"]
[2961,"'GTF2E2'",280,286,281.01,282.336666666667,"05203///Viral carcinogenesis+++05169///Epstein-Barr virus infection+++03022///Basal transcription factors","H00866///Trichothiodystrophy",null,null,"GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005673///transcription factor TFIIE complex+++GO:0005669///transcription factor TFIID complex+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0001097///TFIIH-class transcription factor complex binding+++GO:0005515///protein binding","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter","general transcription factor IIE subunit 2","[T2EB_HUMAN|Reviewed]RecName: Full=Transcription initiation factor IIE subunit beta; Short=TFIIE-beta; AltName: Full=General transcription factor IIE subunit 2;+++[E5RH41_HUMAN|Unreviewed]SubName: Full=Transcription initiation factor IIE subunit beta {ECO:0000313|Ensembl:ENSP00000429921}; Flags: Fragment;+++[E5RIW4_HUMAN|Unreviewed]SubName: Full=Transcription initiation factor IIE subunit beta {ECO:0000313|Ensembl:ENSP00000429312}; Flags: Fragment;+++[E5RK24_HUMAN|Unreviewed]SubName: Full=Transcription initiation factor IIE subunit beta {ECO:0000313|Ensembl:ENSP00000428981};"]
[2972,"'BRF1'",844,937,1002,927.666666666667,{"$nulls":4},"GO:0000126///transcription factor TFIIIB complex","GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0017025///TBP-class protein binding+++GO:0046872///metal ion binding","GO:0006383///transcription by RNA polymerase III+++GO:0006355///regulation of transcription, DNA-templated+++GO:0070897///transcription preinitiation complex assembly","BRF1, RNA polymerase III transcription initiation factor subunit","[TF3B_HUMAN|Reviewed]RecName: Full=Transcription factor IIIB 90 kDa subunit; Short=TFIIIB90; Short=hTFIIIB90; AltName: Full=B-related factor 1; Short=BRF-1; Short=hBRF; AltName: Full=TAF3B2; AltName: Full=TATA box-binding protein-associated factor, RNA polymerase III, subunit 2;+++[A0A024R6P8_HUMAN|Unreviewed]SubName: Full=BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW81909.1};+++[A3KN61_HUMAN|Unreviewed]SubName: Full=BRF1 protein {ECO:0000313|EMBL:AAI33656.1}; SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000480452};+++[F6VUY7_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000369264};+++[F8VS45_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000448723}; Flags: Fragment;+++[F8VWT8_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000449788}; Flags: Fragment;+++[F8VWY1_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000449173}; Flags: Fragment;+++[F8VXJ4_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000448823}; Flags: Fragment;+++[F8W123_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000447521}; Flags: Fragment;+++[H0YIV6_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000450258}; Flags: Fragment;+++[Q3SYD7_HUMAN|Unreviewed]SubName: Full=BRF1 protein {ECO:0000313|EMBL:AAI03862.1}; SubName: Full=Transcription factor IIIB 90 kDa subunit {ECO:0000313|Ensembl:ENSP00000446901};+++[Q3SYD8_HUMAN|Unreviewed]SubName: Full=BRF1 protein {ECO:0000313|EMBL:AAI03861.1};+++[V9HVY2_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 76p {ECO:0000313|EMBL:ACF94480.1};"]
[29767,"'TMOD2'",98.08,123,102,107.693333333333,{"$nulls":4},"GO:0043005///neuron projection+++GO:0005856///cytoskeleton+++GO:0030016///myofibril+++GO:0005737///cytoplasm+++GO:0005865///striated muscle thin filament+++GO:0030426///growth cone","GO:0005523///tropomyosin binding+++GO:0003779///actin binding","GO:0007399///nervous system development+++GO:0051694///pointed-end actin filament capping+++GO:0007611///learning or memory+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway+++GO:0007270///neuron-neuron synaptic transmission+++GO:0030239///myofibril assembly+++GO:0006936///muscle contraction","tropomodulin 2","[TMOD2_HUMAN|Reviewed]RecName: Full=Tropomodulin-2; AltName: Full=Neuronal tropomodulin; Short=N-Tmod;+++[G5EA42_HUMAN|Unreviewed]SubName: Full=Tropomodulin 2 (Neuronal), isoform CRA_a {ECO:0000313|EMBL:EAW77428.1}; SubName: Full=Tropomodulin-2 {ECO:0000313|Ensembl:ENSP00000437743};+++[H0YMA2_HUMAN|Unreviewed]SubName: Full=Tropomodulin-2 {ECO:0000313|Ensembl:ENSP00000453524}; Flags: Fragment;+++[Q4G0W6_HUMAN|Unreviewed]SubName: Full=TMOD2 protein {ECO:0000313|EMBL:AAH36184.1};"]
[2987,"'GUK1'",2022,2392,2603,2339,"01100///Metabolic pathways+++00230///Purine metabolism","H00266///Hereditary spastic paraplegia (SPG)+++H00679///Hypomyelinating leukodystrophy","M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP","R00332///ATP:GMP phosphotransferase   ATP + GMP <=> ADP + GDP+++R02090///ATP:dGMP phosphotransferase   ATP + dGMP <=> ADP + dGDP","GO:0005829///cytosol","GO:0000166///nucleotide binding+++GO:0004385///guanylate kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding","GO:0046060///dATP metabolic process+++GO:0034436///glycoprotein transport+++GO:0006163///purine nucleotide metabolic process+++GO:0016310///phosphorylation+++GO:0006185///dGDP biosynthetic process+++GO:0019673///GDP-mannose metabolic process+++GO:0046037///GMP metabolic process+++GO:0046710///GDP metabolic process+++GO:0046939///nucleotide phosphorylation+++GO:0046711///GDP biosynthetic process+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0046054///dGMP metabolic process+++GO:0046034///ATP metabolic process","guanylate kinase 1","[KGUA_HUMAN|Reviewed]RecName: Full=Guanylate kinase; EC=2.7.4.8; AltName: Full=GMP kinase;+++[A0A024R3U5_HUMAN|Unreviewed]SubName: Full=Guanylate kinase 1, isoform CRA_b {ECO:0000313|EMBL:EAW69854.1};+++[B1ANG9_HUMAN|Unreviewed]SubName: Full=Guanylate kinase {ECO:0000313|Ensembl:ENSP00000355684};+++[B1ANH0_HUMAN|Unreviewed]SubName: Full=Guanylate kinase {ECO:0000313|Ensembl:ENSP00000401832}; Flags: Fragment;+++[B1ANH2_HUMAN|Unreviewed]SubName: Full=Guanylate kinase {ECO:0000313|Ensembl:ENSP00000407604}; Flags: Fragment;+++[B1ANH3_HUMAN|Unreviewed]SubName: Full=Guanylate kinase {ECO:0000313|Ensembl:ENSP00000403664}; Flags: Fragment;+++[B1ANH5_HUMAN|Unreviewed]SubName: Full=Guanylate kinase {ECO:0000313|Ensembl:ENSP00000355682};+++[B1ANH6_HUMAN|Unreviewed]SubName: Full=Guanylate kinase {ECO:0000313|Ensembl:ENSP00000355683};+++[Q6IBG8_HUMAN|Unreviewed]SubName: Full=GUK1 protein {ECO:0000313|EMBL:CAG33117.1}; SubName: Full=Guanylate kinase 1, isoform CRA_a {ECO:0000313|EMBL:EAW69851.1};+++[Q96IN2_HUMAN|Unreviewed]SubName: Full=GUK1 protein {ECO:0000313|EMBL:AAH07369.2}; Flags: Fragment;"]
[29889,"'GNL2'",539,595,621,585,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0003723///RNA binding","GO:0008150///biological_process+++GO:0042254///ribosome biogenesis","G protein nucleolar 2","[NOG2_HUMAN|Reviewed]RecName: Full=Nucleolar GTP-binding protein 2; AltName: Full=Autoantigen NGP-1;+++[H0YG10_HUMAN|Unreviewed]SubName: Full=Nucleolar GTP-binding protein 2 {ECO:0000313|Ensembl:ENSP00000441288}; Flags: Fragment;+++[Q5T0F3_HUMAN|Unreviewed]RecName: Full=Nucleolar GTP-binding protein 2 {ECO:0000256|RuleBase:RU364023};"]
[29927,"'SEC61A1'",11759,12735,12029,12174.3333333333,"04145///Phagosome+++04141///Protein processing in endoplasmic reticulum+++03060///Protein export+++05110///Vibrio cholerae infection","H00541///Autosomal dominant tubulointerstitial kidney disease (ADTKD)+++H02011///Familial juvenile hyperuricemic nephropathy (HNFJ)","M00401///Sec61 complex",null,"GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005784///Sec61 translocon complex+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005791///rough endoplasmic reticulum","GO:0005515///protein binding+++GO:0043022///ribosome binding+++GO:0008320///protein transmembrane transporter activity+++GO:0005048///signal sequence binding","GO:0039019///pronephric nephron development+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane+++GO:0006613///cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation+++GO:0034341///response to interferon-gamma+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0045047///protein targeting to ER+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane","Sec61 translocon alpha 1 subunit","[S61A1_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec61 subunit alpha isoform 1; Short=Sec61 alpha-1;+++[B3KME8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10827 fis, clone NT2RP4001117, highly similar to Protein transport protein Sec61 subunit alpha isoform 1 {ECO:0000313|EMBL:BAG50960.1}; SubName: Full=cDNA FLJ14546 fis, clone NT2RM2001613, highly similar to Protein transport protein Sec61 subunit alpha isoform 1 {ECO:0000313|EMBL:BAG51323.1};+++[B3KNF6_HUMAN|Unreviewed]SubName: Full=Sec61 alpha 1 subunit (S. cerevisiae), isoform CRA_c {ECO:0000313|EMBL:EAW79326.1}; SubName: Full=cDNA FLJ14517 fis, clone NT2RM1000833, highly similar to Protein transport protein Sec61 subunit alpha isoform 1 {ECO:0000313|EMBL:BAG51318.1}; SubName: Full=cDNA FLJ90225 fis, clone NT2RM1000855, highly similar to Protein transport protein Sec61 subunit alpha isoform 1 {ECO:0000313|EMBL:BAG51989.1};+++[B4DR61_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59739, highly similar to Protein transport protein Sec61 subunit alpha isoform 1 {ECO:0000313|EMBL:BAG61173.1};+++[C9JXC6_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec61 subunit alpha isoform 1 {ECO:0000313|Ensembl:ENSP00000419172}; Flags: Fragment;"]
[29935,"'RPA4'",2,0,1,1,"03430///Mismatch repair+++03460///Fanconi anemia pathway+++03440///Homologous recombination+++03420///Nucleotide excision repair+++03030///DNA replication",null,"M00288///RPA complex",null,"GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0000781///chromosome, telomeric region+++GO:0005654///nucleoplasm+++GO:0000794///condensed nuclear chromosome+++GO:0000785///chromatin+++GO:0005662///DNA replication factor A complex","GO:0003684///damaged DNA binding+++GO:0005515///protein binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding","GO:0006310///DNA recombination+++GO:0006298///mismatch repair+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006289///nucleotide-excision repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006265///DNA topological change+++GO:0051096///positive regulation of helicase activity+++GO:0006312///mitotic recombination+++GO:0030491///heteroduplex formation+++GO:0006281///DNA repair+++GO:0007131///reciprocal meiotic recombination+++GO:0033260///nuclear DNA replication+++GO:2000001///regulation of DNA damage checkpoint+++GO:0006270///DNA replication initiation+++GO:0007004///telomere maintenance via telomerase+++GO:0006284///base-excision repair+++GO:0000077///DNA damage checkpoint+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006260///DNA replication+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000722///telomere maintenance via recombination","replication protein A4","[RFA4_HUMAN|Reviewed]RecName: Full=Replication protein A 30 kDa subunit; Short=RP-A p30; AltName: Full=Replication factor A protein 4; Short=RF-A protein 4;"]
[29969,"'MDFIC'",226,248,187,220.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0030332///cyclin binding+++GO:0008134///transcription factor binding+++GO:0030957///Tat protein binding","GO:0030111///regulation of Wnt signaling pathway+++GO:0007257///activation of JUN kinase activity+++GO:0042308///negative regulation of protein import into nucleus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0016032///viral process+++GO:0050434///positive regulation of viral transcription","MyoD family inhibitor domain containing","[MDFIC_HUMAN|Reviewed]RecName: Full=MyoD family inhibitor domain-containing protein; AltName: Full=I-mfa domain-containing protein; Short=hIC;+++[A0A087X231_HUMAN|Unreviewed]SubName: Full=MyoD family inhibitor domain-containing protein {ECO:0000313|Ensembl:ENSP00000484656};+++[C9J104_HUMAN|Unreviewed]SubName: Full=MyoD family inhibitor domain-containing protein {ECO:0000313|Ensembl:ENSP00000412153};+++[C9J784_HUMAN|Unreviewed]SubName: Full=MyoD family inhibitor domain-containing protein {ECO:0000313|Ensembl:ENSP00000418337}; Flags: Fragment;+++[H7BZY3_HUMAN|Unreviewed]SubName: Full=MyoD family inhibitor domain-containing protein {ECO:0000313|Ensembl:ENSP00000392098}; Flags: Fragment;+++[H7C4B9_HUMAN|Unreviewed]SubName: Full=MyoD family inhibitor domain-containing protein {ECO:0000313|Ensembl:ENSP00000416668}; Flags: Fragment;+++[J3KN13_HUMAN|Unreviewed]SubName: Full=MyoD family inhibitor domain-containing protein {ECO:0000313|Ensembl:ENSP00000257724};"]
[29978,"'UBQLN2'",2165,2209,1742,2038.66666666667,"04141///Protein processing in endoplasmic reticulum","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:2000785///regulation of autophagosome assembly+++GO:1900186///negative regulation of clathrin-dependent endocytosis+++GO:1904021///negative regulation of G protein-coupled receptor internalization+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0016241///regulation of macroautophagy","ubiquilin 2","[UBQL2_HUMAN|Reviewed]RecName: Full=Ubiquilin-2; AltName: Full=Chap1; AltName: Full=DSK2 homolog; AltName: Full=Protein linking IAP with cytoskeleton 2; Short=PLIC-2; Short=hPLIC-2; AltName: Full=Ubiquitin-like product Chap1/Dsk2;"]
[29997,"'NOP53'",2561,2373,2393,2442.33333333333,"05168///Herpes simplex infection",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular+++GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0033553///rDNA heterochromatin+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0002039///p53 binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0008097///5S rRNA binding","GO:0071456///cellular response to hypoxia+++GO:1902570///protein localization to nucleolus+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0051726///regulation of cell cycle+++GO:0031333///negative regulation of protein complex assembly+++GO:1903006///positive regulation of protein K63-linked deubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0042254///ribosome biogenesis+++GO:0000027///ribosomal large subunit assembly+++GO:0006364///rRNA processing+++GO:0042981///regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0001932///regulation of protein phosphorylation+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0039535///regulation of RIG-I signaling pathway+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:0051898///negative regulation of protein kinase B signaling+++GO:1903715///regulation of aerobic respiration+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:1990173///protein localization to nucleoplasm","NOP53 ribosome biogenesis factor","[NOP53_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein NOP53 {ECO:0000305}; AltName: Full=Glioma tumor suppressor candidate region gene 2 protein {ECO:0000312|HGNC:HGNC:4333}; AltName: Full=Protein interacting with carboxyl terminus 1 {ECO:0000303|PubMed:15355975}; Short=PICT-1 {ECO:0000303|PubMed:15355975}; AltName: Full=p60 {ECO:0000303|PubMed:10196275};+++[M0QX73_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000468948}; Flags: Fragment;+++[M0QYZ9_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000470190}; Flags: Fragment;+++[M0QZ34_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000470263}; Flags: Fragment;+++[M0QZU5_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NOP53 {ECO:0000313|Ensembl:ENSP00000470773}; Flags: Fragment;+++[Q96CS0_HUMAN|Unreviewed]SubName: Full=GLTSCR2 protein {ECO:0000313|EMBL:AAH14009.2}; Flags: Fragment;"]
[3015,"'H2AFZ'",538,525,623,562,"05322///Systemic lupus erythematosus+++05034///Alcoholism+++04217///Necroptosis",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0001740///Barr body+++GO:0005720///nuclear heterochromatin+++GO:0005634///nucleus+++GO:0005719///nuclear euchromatin+++GO:0000790///nuclear chromatin+++GO:0000786///nucleosome+++GO:0005694///chromosome","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0031490///chromatin DNA binding+++GO:0005515///protein binding+++GO:0031492///nucleosomal DNA binding","GO:0006325///chromatin organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071392///cellular response to estradiol stimulus","H2A histone family member Z","[H2AZ_HUMAN|Reviewed]RecName: Full=Histone H2A.Z; Short=H2A/z;"]
[3039,"'HBA1'",0,0,1,0.333333333333333,"05144///Malaria+++05143///African trypanosomiasis","H00228///Thalassemia",null,null,"GO:0031838///haptoglobin-hemoglobin complex+++GO:0005833///hemoglobin complex+++GO:0070062///extracellular exosome+++GO:0071682///endocytic vesicle lumen+++GO:0072562///blood microparticle+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005615///extracellular space","GO:0019825///oxygen binding+++GO:0005506///iron ion binding+++GO:0004601///peroxidase activity+++GO:0020037///heme binding+++GO:0005515///protein binding+++GO:0031720///haptoglobin binding+++GO:0046872///metal ion binding+++GO:0043177///organic acid binding+++GO:0005344///oxygen carrier activity","GO:0051291///protein heterooligomerization+++GO:0010942///positive regulation of cell death+++GO:0042542///response to hydrogen peroxide+++GO:0098869///cellular oxidant detoxification+++GO:0042744///hydrogen peroxide catabolic process+++GO:0015671///oxygen transport+++GO:0015701///bicarbonate transport+++GO:0006898///receptor-mediated endocytosis","hemoglobin subunit alpha 1","[HBA_HUMAN|Reviewed]RecName: Full=Hemoglobin subunit alpha; AltName: Full=Alpha-globin; AltName: Full=Hemoglobin alpha chain;+++[D1MGQ2_HUMAN|Unreviewed]SubName: Full=Alpha-2 globin chain {ECO:0000313|EMBL:ADV78002.1}; SubName: Full=Delta globin {ECO:0000313|EMBL:ACZ54507.1}; SubName: Full=HCG1745306, isoform CRA_b {ECO:0000313|EMBL:EAW85863.1};+++[E1B2D1_HUMAN|Unreviewed]SubName: Full=Hemoglobin alpha-1 globin chain variant {ECO:0000313|EMBL:ADM45275.1}; Flags: Fragment;+++[E9M4D4_HUMAN|Unreviewed]SubName: Full=Hemoglobin alpha-1 globin chain {ECO:0000313|EMBL:ADV59921.1}; Flags: Fragment;+++[I1VZV6_HUMAN|Unreviewed]SubName: Full=Hemoglobin alpha 1 {ECO:0000313|EMBL:AFI57164.1};+++[Q6J1Z9_HUMAN|Unreviewed]SubName: Full=Hemoglobin alpha 1 {ECO:0000313|EMBL:AAT36649.1}; Flags: Fragment;+++[Q86YL2_HUMAN|Unreviewed]SubName: Full=Hemoglobin alpha-1 chain {ECO:0000313|EMBL:AAO42516.1}; Flags: Fragment;+++[Q86YQ4_HUMAN|Unreviewed]SubName: Full=Alpha-1 globin {ECO:0000313|EMBL:AAO22464.1}; Flags: Fragment;+++[Q9BX83_HUMAN|Unreviewed]SubName: Full=Hemoglobin alpha 1 globin chain {ECO:0000313|EMBL:AAK15770.1}; Flags: Fragment;+++[Q9NQT3_HUMAN|Unreviewed]SubName: Full=Alpha one globin {ECO:0000313|EMBL:AAF90195.1}; Flags: Fragment;+++[U6A216_HUMAN|Unreviewed]SubName: Full=Mutant hemoglobin alpha 1 globin chain {ECO:0000313|EMBL:AHA12104.1}; SubName: Full=Mutant hemoglobin alpha 2 globin chain {ECO:0000313|EMBL:AHA12099.1}; Flags: Fragment;+++[V9GZG8_HUMAN|Unreviewed]SubName: Full=Allantoate permease {ECO:0000313|EMBL:AAA52629.1}; Flags: Fragment;"]
[3069,"'HDLBP'",24138,23022,20601,22587,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0034364///high-density lipoprotein particle","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0008289///lipid binding","GO:0006629///lipid metabolic process+++GO:0008202///steroid metabolic process+++GO:0034384///high-density lipoprotein particle clearance+++GO:0008203///cholesterol metabolic process+++GO:0006869///lipid transport","high density lipoprotein binding protein","[VIGLN_HUMAN|Reviewed]RecName: Full=Vigilin; AltName: Full=High density lipoprotein-binding protein; Short=HDL-binding protein;+++[A0A024R4E5_HUMAN|Unreviewed]SubName: Full=High density lipoprotein binding protein (Vigilin), isoform CRA_a {ECO:0000313|EMBL:EAW71254.1}; SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000312042};+++[B2R5V9_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92652, highly similar to Homo sapiens high density lipoprotein binding protein (vigilin)(HDLBP), mRNA {ECO:0000313|EMBL:BAG35256.1};+++[C9J5E5_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000405109}; Flags: Fragment;+++[C9J739_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000397799}; Flags: Fragment;+++[C9JB08_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000391773}; Flags: Fragment;+++[C9JBS3_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000403693}; Flags: Fragment;+++[C9JE93_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000396202}; Flags: Fragment;+++[C9JEJ8_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000390942}; Flags: Fragment;+++[C9JES8_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000416559}; Flags: Fragment;+++[C9JHN6_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000390290}; Flags: Fragment;+++[C9JHS7_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000396964}; Flags: Fragment;+++[C9JHS9_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000396959}; Flags: Fragment;+++[C9JHZ8_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000403913}; Flags: Fragment;+++[C9JIZ1_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000403807}; Flags: Fragment;+++[C9JK79_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000413891}; Flags: Fragment;+++[C9JMQ6_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000408582}; Flags: Fragment;+++[C9JQ82_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000409868}; Flags: Fragment;+++[C9JT62_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000394205}; Flags: Fragment;+++[C9JZI8_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000387782}; Flags: Fragment;+++[H0Y394_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000362389}; Flags: Fragment;+++[H7BZC3_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000388876}; Flags: Fragment;+++[H7C0A4_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000393766}; Flags: Fragment;+++[H7C2D1_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000405180}; Flags: Fragment;+++[H7C3D0_HUMAN|Unreviewed]SubName: Full=Vigilin {ECO:0000313|Ensembl:ENSP00000411211}; Flags: Fragment;+++[L8ECQ0_HUMAN|Unreviewed]SubName: Full=Alternative protein HDLBP {ECO:0000313|EMBL:CCQ43952.1};+++[Q2HJC8_HUMAN|Unreviewed]SubName: Full=HDLBP protein {ECO:0000313|EMBL:AAI13121.1}; Flags: Fragment;+++[Q96CF6_HUMAN|Unreviewed]SubName: Full=HDLBP protein {ECO:0000313|EMBL:AAH14305.2}; Flags: Fragment;"]
[30819,"'KCNIP2'",11,5,3,6.33333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0008076///voltage-gated potassium channel complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0034705///potassium channel complex","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0046923///ER retention sequence binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005250///A-type (transient outward) potassium channel activity+++GO:0005509///calcium ion binding+++GO:0005267///potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:0042802///identical protein binding+++GO:0047485///protein N-terminus binding+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization+++GO:0044325///ion channel binding","GO:1903766///positive regulation of potassium ion export across plasma membrane+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:0045163///clustering of voltage-gated potassium channels+++GO:0006811///ion transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:1903818///positive regulation of voltage-gated potassium channel activity+++GO:0086009///membrane repolarization+++GO:0034765///regulation of ion transmembrane transport+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0008016///regulation of heart contraction+++GO:0005513///detection of calcium ion+++GO:0007268///chemical synaptic transmission+++GO:0006936///muscle contraction+++GO:0007165///signal transduction","potassium voltage-gated channel interacting protein 2","[KCIP2_HUMAN|Reviewed]RecName: Full=Kv channel-interacting protein 2; Short=KChIP2 {ECO:0000303|PubMed:11684073}; AltName: Full=A-type potassium channel modulatory protein 2; AltName: Full=Cardiac voltage-gated potassium channel modulatory subunit; AltName: Full=Potassium channel-interacting protein 2;+++[A0A2R8Y6D7_HUMAN|Unreviewed]SubName: Full=Kv channel-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000495474};+++[A6NFF4_HUMAN|Unreviewed]SubName: Full=Kv channel-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000359063};+++[A6QL43_HUMAN|Unreviewed]SubName: Full=Kv channel interacting protein 2 {ECO:0000313|EMBL:AAX58112.1}; Flags: Fragment;+++[B3KSZ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ37349 fis, clone BRAMY2021746, highly similar to Kv channel-interacting protein 2 {ECO:0000313|EMBL:BAG52907.1};+++[Q09MK0_HUMAN|Unreviewed]SubName: Full=Kv channel interacting protein 2 transcript variant 9 {ECO:0000313|EMBL:ABI51986.1};"]
[309,"'ANXA6'",4014,3383,3593,3663.33333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0048471///perinuclear region of cytoplasm+++GO:0042470///melanosome+++GO:0005925///focal adhesion+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0031902///late endosome membrane+++GO:0062023///collagen-containing extracellular matrix","GO:0015276///ligand-gated ion channel activity+++GO:0008289///lipid binding+++GO:0042803///protein homodimerization activity+++GO:0051015///actin filament binding+++GO:0005509///calcium ion binding+++GO:0008201///heparin binding+++GO:0048306///calcium-dependent protein binding+++GO:0005525///GTP binding+++GO:0001786///phosphatidylserine binding+++GO:0005262///calcium channel activity+++GO:0005544///calcium-dependent phospholipid binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0015485///cholesterol binding+++GO:0038023///signaling receptor activity+++GO:0035374///chondroitin sulfate binding+++GO:0044877///protein-containing complex binding","GO:0051560///mitochondrial calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0051283///negative regulation of sequestering of calcium ion+++GO:0001755///neural crest cell migration+++GO:0070509///calcium ion import+++GO:0006937///regulation of muscle contraction+++GO:0031214///biomineral tissue development+++GO:0070588///calcium ion transmembrane transport+++GO:0006816///calcium ion transport+++GO:0003418///growth plate cartilage chondrocyte differentiation+++GO:0097190///apoptotic signaling pathway+++GO:0051260///protein homooligomerization","annexin A6","[ANXA6_HUMAN|Reviewed]RecName: Full=Annexin A6; AltName: Full=67 kDa calelectrin; AltName: Full=Annexin VI; AltName: Full=Annexin-6; AltName: Full=Calphobindin-II; Short=CPB-II; AltName: Full=Chromobindin-20; AltName: Full=Lipocortin VI; AltName: Full=Protein III; AltName: Full=p68; AltName: Full=p70;+++[A0A0S2Z2Z6_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; Flags: Fragment;+++[A0A0S2Z301_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[A0A0S2Z377_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; Flags: Fragment;+++[E5RFF0_HUMAN|Unreviewed]SubName: Full=Annexin A6 {ECO:0000313|Ensembl:ENSP00000428916}; Flags: Fragment;+++[E5RI05_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[E5RIU8_HUMAN|Unreviewed]SubName: Full=Annexin A6 {ECO:0000313|Ensembl:ENSP00000430663};+++[E5RJF5_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; Flags: Fragment;+++[E5RJR0_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; Flags: Fragment;+++[E5RK63_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; Flags: Fragment;+++[E5RK69_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[E7EMC6_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[H0YC77_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540}; Flags: Fragment;"]
[3106,"'HLA-B'",12558.68,17337.75,20028.56,16641.6633333333,"05330///Allograft rejection+++05168///Herpes simplex infection+++05203///Viral carcinogenesis+++04145///Phagosome+++05163///Human cytomegalovirus infection+++04514///Cell adhesion molecules (CAMs)+++04940///Type I diabetes mellitus+++05169///Epstein-Barr virus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05165///Human papillomavirus infection+++05166///HTLV-I infection+++04144///Endocytosis+++05332///Graft-versus-host disease+++04612///Antigen processing and presentation+++05416///Viral myocarditis+++04218///Cellular senescence+++05320///Autoimmune thyroid disease","H01713///Diffuse panbronchiolitis+++H00344///Leprosy+++H01476///Behcet disease+++H01507///Seronegative arthritis (SpA)+++H01694///Stevens-Johnson syndrome and toxic epidermal necrolysis+++H01674///Ankylosing spondylitis",null,null,"GO:0031901///early endosome membrane+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0030667///secretory granule membrane+++GO:0016020///membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0055038///recycling endosome membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0030670///phagocytic vesicle membrane+++GO:0042612///MHC class I protein complex+++GO:0009986///cell surface+++GO:0012507///ER to Golgi transport vesicle membrane","GO:0003674///molecular_function+++GO:0005102///signaling receptor binding+++GO:0046977///TAP binding+++GO:0051087///chaperone binding+++GO:0005515///protein binding+++GO:0042605///peptide antigen binding","GO:0043312///neutrophil degranulation+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0016032///viral process+++GO:0002667///regulation of T cell anergy+++GO:0050776///regulation of immune response+++GO:0002376///immune system process+++GO:0032675///regulation of interleukin-6 production+++GO:0006955///immune response+++GO:0060337///type I interferon signaling pathway+++GO:0032655///regulation of interleukin-12 production+++GO:0006952///defense response+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0045087///innate immune response+++GO:0002480///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent+++GO:0008150///biological_process+++GO:0016567///protein ubiquitination+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0042270///protection from natural killer cell mediated cytotoxicity+++GO:2001198///regulation of dendritic cell differentiation+++GO:0019882///antigen processing and presentation+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0002486///antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent","major histocompatibility complex, class I, B",{"$cut":{"chars":32759,"head":"[1B07_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-7 alpha chain; AltName: Full=MHC class I antigen B*7; Flags: Precursor;+++[1B08_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-8 alpha chain; AltName: Full=MHC class I antigen B*8; Flags: Precursor;+++[1B13_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-13 alpha chain; AltName: Full=MHC class I antigen B*13; Flags: Precursor;+++[1B14_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-14 alpha chain; AltName: Full=MHC class I antigen B*14; Flags: Precursor;+++[1B15_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-15 alpha chain; AltName: Full=MHC class I antigen B*15; Flags: Precursor;+++[1B18_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-18 alpha chain; AltName: Full=MHC class I antigen B*18; Flags: Precursor;+++[1B27_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-27 alpha chain; AltName: Full=MHC class I antigen B*27; Flags: Precursor;+++[1B35_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-35 alpha chain; AltName: Full=MHC class I antigen B*35; Flags: Precursor;+++[1B37_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-37 alpha chain; AltName: Full=MHC class I antigen B*37; Flags: Precursor;+++[1B38_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-38 alpha chain; AltName: Full=Bw-4; AltName: Full=MHC class I antigen B*38; Flags: Precursor;+++[1B39_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-39 alpha chain; AltName: Full=MHC class I antigen B*39; Flags: Precursor;+++[1B40_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-40 alpha chain; AltName: Full=Bw-60; AltName: Full=MHC class I antigen B*40; Flags: Precursor;+++[1B41_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-41 alpha chain; AltName: Full=Bw-41; AltName: Full=MHC class I antigen B*41; Flags: Precursor;+++[1B42_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-42 alpha chain; AltName: Full=MHC class I antigen B*42; Flags: Precursor;+++[1B44_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-44 alpha chain; AltName: Full=Bw-44; AltName: Full=MHC class I antigen B*44; Flags: Precursor;+++[1B45_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-45 alpha chain; AltName: Full=Bw-45; AltName: Full=MHC class I antigen B*45; Flags: Precursor;+++[1B46_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-46 alpha chain; AltName: Full=Bw-46; AltName: Full=MHC class I antigen B*46; Flags: Precursor;+++[1B47_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-47 alpha chain; AltName: Full=Bw-47; AltName: Full=MHC class I antigen B*47; Flags: Precursor;+++[1B48_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-48 alpha chain; AltName: Full=Bw-48; AltName: Full=MHC class I antigen B*48; Flags: Precursor;+++[1B49_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-49 alpha chain; AltName: Full=HLA class I histocompatibility antigen, B-21 alpha chain; AltName: Full=MHC class I antigen B*49; Flags: Precursor;+++[1B50_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-50 alpha chain; AltName: Full=Bw-50; AltName: Full=HLA class I histocompatibility antigen, B-21 alpha chain; AltName: Full=MHC class I antigen B*50; Flags: Precursor;+++[1B51_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-51 alpha chain; AltName: Full=MHC class I antigen B*51; Flags: Precursor;+++[1B52_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-52 alpha chain; AltName: Full=Bw-52; AltName: Full=HLA class I histocompatibility antigen, B-5 alpha chain; AltName: Full=MHC class I antigen B*52; Flags: Precursor;+++[1B53_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, B-53 alpha chain; AltName: Full=Bw-53; AltName: Full=MHC class I antigen B*53; Fla"}}]
[3134,"'HLA-F'",256,428.01,537.13,407.046666666667,"04514///Cell adhesion molecules (CAMs)+++04612///Antigen processing and presentation+++05203///Viral carcinogenesis+++05169///Epstein-Barr virus infection+++05416///Viral myocarditis+++05332///Graft-versus-host disease+++04144///Endocytosis+++05163///Human cytomegalovirus infection+++04940///Type I diabetes mellitus+++05168///Herpes simplex infection+++04145///Phagosome+++05166///HTLV-I infection+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04218///Cellular senescence+++05165///Human papillomavirus infection","H01507///Seronegative arthritis (SpA)+++H00344///Leprosy+++H01694///Stevens-Johnson syndrome and toxic epidermal necrolysis+++H01674///Ankylosing spondylitis+++H01713///Diffuse panbronchiolitis+++H01476///Behcet disease",null,null,"GO:0055038///recycling endosome membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0031901///early endosome membrane+++GO:0042612///MHC class I protein complex+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0009986///cell surface+++GO:0000139///Golgi membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0046979///TAP2 binding+++GO:0042605///peptide antigen binding+++GO:0005515///protein binding+++GO:0046978///TAP1 binding+++GO:0005102///signaling receptor binding","GO:0002476///antigen processing and presentation of endogenous peptide antigen via MHC class Ib+++GO:0019882///antigen processing and presentation+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0050776///regulation of immune response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0060337///type I interferon signaling pathway+++GO:0006955///immune response+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0001916///positive regulation of T cell mediated cytotoxicity+++GO:0002480///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent+++GO:0002376///immune system process","major histocompatibility complex, class I, F","[HLAF_HUMAN|Reviewed]RecName: Full=HLA class I histocompatibility antigen, alpha chain F; AltName: Full=CDA12; AltName: Full=HLA F antigen; AltName: Full=Leukocyte antigen F; AltName: Full=MHC class I antigen F; Flags: Precursor;+++[A0A0D9SF55_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000486309}; Flags: Fragment;+++[A0A0D9SFW8_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000486947}; Flags: Fragment;+++[A0A0G2JH66_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000373123};+++[A0A0G2JNV5_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000482177};+++[A0A0G2JPA3_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000483269};+++[A0A140T8X0_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000366040}; Flags: Fragment;+++[A0A140T908_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000388133}; Flags: Fragment;+++[A0A140T925_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000389555}; Flags: Fragment;+++[A0A140T939_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000390887}; Flags: Fragment;+++[A0A140T9A3_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000396776}; Flags: Fragment;+++[A0A140T9B7_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000397705};+++[A0A140T9C2_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000398913}; Flags: Fragment;+++[A0A140T9C8_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000399120}; Flags: Fragment;+++[A0A140T9D2_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000399043}; Flags: Fragment;+++[A0A140T9D9_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000400112}; Flags: Fragment;+++[A0A140T9I8_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000404395}; Flags: Fragment;+++[A0A140T9J8_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000405198}; Flags: Fragment;+++[A0A140T9K3_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000405190}; Flags: Fragment;+++[A0A140T9M4_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000407836}; Flags: Fragment;+++[A0A140T9P9_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000409934}; Flags: Fragment;+++[A0A140T9S6_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000412140}; Flags: Fragment;+++[A0A140T9V0_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000414318}; Flags: Fragment;+++[A0A140T9W3_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000414500}; Flags: Fragment;+++[A0A140T9W5_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000415017}; Flags: Fragment;+++[A0A140T9W7_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000415401}; Flags: Fragment;+++[A0A140T9X6_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000416426}; Flags: Fragment;+++[A0A1D5RMP3_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000400299}; Flags: Fragment;+++[A0A1V0E3T9_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08458.1}; Flags: Fragment;+++[A0A1V0E3U0_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08452.1}; Flags: Fragment;+++[A0A1V0E3U1_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08454.1}; Flags: Fragment;+++[A0A1V0E3U3_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08455.1}; Flags: Fragment;+++[A0A1V0E3V1_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08453.1}; Flags: Fragment;+++[A0A1V0E3V5_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08456.1}; Flags: Fragment;+++[A0A1V0E3W4_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08450.1}; Flags: Fragment;+++[A0A1V0E3W8_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08457.1}; Flags: Fragment;+++[A0A1V0E3X2_HUMAN|Unreviewed]SubName: Full=HLA-F {ECO:0000313|EMBL:ARB08451.1}; Flags: Fragment;+++[D0EV57_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000345828}; SubName: Full=MHC class I antigen {ECO:0000313|EMBL:ACX50639.1};+++[H0Y4J4_HUMAN|Unreviewed]SubName: Full=HLA class I histocompatibility antigen, alpha chain F {ECO:0000313|Ensembl:ENSP00000392251}; Flags: Fragment;+++[O78094_HUMAN|Unreviewed]SubName: Full=HLA-F protein {ECO:0000313|EMBL:BAA32747.1}; Flags: Fragment;+++[Q54A71_HUMAN|Unreviewed]SubName: Full=HLA-F protein {ECO:0000313|EMBL:BAF31252.1}; SubName: Full=Major histocompatibility complex, class I, F {ECO:0000313|EMBL:BAC54915.1};+++[Q5JZ47_HUMAN|Unreviewed]SubName: Full=Major histocompatibility complex, class I, F {ECO:0000313|EMBL:CAI20360.1};+++[Q5JZ48_HUMAN|Unreviewed]SubName: Full=Major histocompatibility complex, class I, F {ECO:0000313|EMBL:CAI20359.1};+++[Q6DU20_HUMAN|Unreviewed]SubName: Full=MHC class Ib antigen {ECO:0000313|EMBL:AAT73238.1};+++[Q6DU28_HUMAN|Unreviewed]SubName: Full=MHC class Ib antigen {ECO:0000313|EMBL:AAT73230.1};+++[Q7YP62_HUMAN|Unreviewed]SubName: Full=MHC class Ib antigen {ECO:0000313|EMBL:AAP94210.1}; Flags: Fragment;+++[Q861E9_HUMAN|Unreviewed]SubName: Full=MHC class I antigen {ECO:0000313|EMBL:AAO34407.1}; Flags: Fragment;+++[Q861F0_HUMAN|Unreviewed]SubName: Full=Nonclassical MHC class I antigen {ECO:0000313|EMBL:AAO37689.1}; Flags: Fragment;"]
[3161,"'HMMR'",9,1,11,7,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0005813///centrosome+++GO:0015630///microtubule cytoskeleton+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005540///hyaluronic acid binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0030214///hyaluronan catabolic process","hyaluronan mediated motility receptor","[HMMR_HUMAN|Reviewed]RecName: Full=Hyaluronan mediated motility receptor; AltName: Full=Intracellular hyaluronic acid-binding protein; AltName: Full=Receptor for hyaluronan-mediated motility; AltName: CD_antigen=CD168;+++[B9UCQ3_HUMAN|Unreviewed]SubName: Full=Hyaluronan-mediated motility receptor {ECO:0000313|EMBL:ACD35245.1}; Flags: Fragment;+++[E5RI30_HUMAN|Unreviewed]SubName: Full=Hyaluronan mediated motility receptor {ECO:0000313|Ensembl:ENSP00000428481}; Flags: Fragment;+++[E5RIH2_HUMAN|Unreviewed]SubName: Full=Hyaluronan mediated motility receptor {ECO:0000313|Ensembl:ENSP00000428406}; Flags: Fragment;+++[Q05D84_HUMAN|Unreviewed]SubName: Full=HMMR protein {ECO:0000313|EMBL:AAH17793.1}; Flags: Fragment;+++[Q05DM0_HUMAN|Unreviewed]SubName: Full=HMMR protein {ECO:0000313|EMBL:AAH06984.1}; Flags: Fragment;+++[Q6NSC0_HUMAN|Unreviewed]SubName: Full=HMMR protein {ECO:0000313|EMBL:AAH70281.1}; Flags: Fragment;+++[Q6PG44_HUMAN|Unreviewed]SubName: Full=HMMR protein {ECO:0000313|EMBL:AAH57235.1}; Flags: Fragment;+++[Q6PIR6_HUMAN|Unreviewed]SubName: Full=HMMR protein {ECO:0000313|EMBL:AAH30505.1}; Flags: Fragment;"]
[317671,"'RFESD'",6,6,7,6.33333333333333,{"$nulls":5},"GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process","Rieske Fe-S domain containing","[RFESD_HUMAN|Reviewed]RecName: Full=Rieske domain-containing protein;+++[A0A024RAR3_HUMAN|Unreviewed]SubName: Full=LOC317671, isoform CRA_b {ECO:0000313|EMBL:EAW96044.1};+++[D6RBY0_HUMAN|Unreviewed]SubName: Full=Rieske domain-containing protein {ECO:0000313|Ensembl:ENSP00000422520}; Flags: Fragment;+++[D6RJG8_HUMAN|Unreviewed]SubName: Full=Rieske domain-containing protein {ECO:0000313|Ensembl:ENSP00000425632};"]
[319089,"'TTC6'",0,2,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005902///microvillus+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0008134///transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0019904///protein domain specific binding","GO:0045931///positive regulation of mitotic cell cycle+++GO:0043065///positive regulation of apoptotic process+++GO:0071542///dopaminergic neuron differentiation+++GO:0009653///anatomical structure morphogenesis+++GO:0032197///transposition, RNA-mediated+++GO:0060741///prostate gland stromal morphogenesis+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0060528///secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0045666///positive regulation of neuron differentiation+++GO:0042593///glucose homeostasis+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0060738///epithelial-mesenchymal signaling involved in prostate gland development+++GO:0006310///DNA recombination+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0032355///response to estradiol+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021904///dorsal/ventral neural tube patterning+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0042445///hormone metabolic process+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0060487///lung epithelial cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006338///chromatin remodeling+++GO:0061144///alveolar secondary septum development+++GO:1902691///respiratory basal cell differentiation+++GO:0048665///neuron fate specification","tetratricopeptide repeat domain 6","[TTC6_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 6; Short=TPR repeat protein 6;+++[G3V2C3_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 6 {ECO:0000313|Ensembl:ENSP00000450572}; Flags: Fragment;+++[G3V3A5_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 6 {ECO:0000313|Ensembl:ENSP00000451131};+++[G3V435_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 6 {ECO:0000313|Ensembl:ENSP00000451566};+++[G5E9W5_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 6 {ECO:0000313|Ensembl:ENSP00000419204};+++[H0YJ01_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 6 {ECO:0000313|Ensembl:ENSP00000450568}; Flags: Fragment;+++[Q3SY86_HUMAN|Unreviewed]SubName: Full=TTC6 protein {ECO:0000313|EMBL:AAI03917.1};+++[Q3SY87_HUMAN|Unreviewed]SubName: Full=TTC6 protein {ECO:0000313|EMBL:AAI03916.1}; SubName: Full=Tetratricopeptide repeat protein 6 {ECO:0000313|Ensembl:ENSP00000371757};"]
[3219,"'HOXB9'",4,12,21,12.3333333333333,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm","GO:0043565///sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0030879///mammary gland development+++GO:0009952///anterior/posterior pattern specification+++GO:0048706///embryonic skeletal system development+++GO:0060326///cell chemotaxis+++GO:0007275///multicellular organism development","homeobox B9","[HXB9_HUMAN|Reviewed]RecName: Full=Homeobox protein Hox-B9; AltName: Full=Homeobox protein Hox-2.5; AltName: Full=Homeobox protein Hox-2E;+++[B3KPJ1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31852 fis, clone NT2RP7000812, highly similar to HOMEOBOX PROTEIN HOX-B9 {ECO:0000313|EMBL:BAG51703.1};"]
[326,"'AIRE'",3,1,0,1.33333333333333,"04120///Ubiquitin mediated proteolysis+++05340///Primary immunodeficiency","H01972///Autoimmune polyendocrinopathy syndrome type 1+++H00107///Other well-defined immunodeficiency syndromes",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0045182///translation regulator activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0042393///histone binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding","GO:0032602///chemokine production+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000410///regulation of thymocyte migration+++GO:0045060///negative thymic T cell selection+++GO:0006959///humoral immune response+++GO:0006955///immune response+++GO:0006417///regulation of translation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0002509///central tolerance induction to self antigen+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002458///peripheral T cell tolerance induction+++GO:0097536///thymus epithelium morphogenesis","autoimmune regulator","[AIRE_HUMAN|Reviewed]RecName: Full=Autoimmune regulator; AltName: Full=Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; Short=APECED protein;+++[A5A8N0_HUMAN|Unreviewed]SubName: Full=Autoimmune regulator {ECO:0000313|EMBL:BAF62470.1}; Flags: Fragment;"]
[3292,"'HSD17B1'",15,18,24,19,"04913///Ovarian steroidogenesis+++00140///Steroid hormone biosynthesis+++01100///Metabolic pathways",null,null,"R08980///11beta,17beta-dihydroxy-4-androsten-3-one:NADP+ 17-oxidoreductase   11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H++++R08945///11beta,17beta-dihydroxy-4-androsten-3-one:NAD+ 17-oxidoreductase   11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H++++R02353///Estradiol-17beta:NADP+ 17-oxidoreductase   Estradiol-17beta + NADP+ <=> Estrone + NADPH + H++++R04681///Estriol:NAD+ 17-oxidoreductase   Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H++++R02352///Estradiol-17beta:NAD+ 17-oxidoreductase   Estradiol-17beta + NAD+ <=> Estrone + NADH + H++++R04682///Estriol:NADP+ 17-oxidoreductase   Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003824///catalytic activity+++GO:0005496///steroid binding+++GO:0016491///oxidoreductase activity+++GO:0047035///testosterone dehydrogenase (NAD+) activity+++GO:0004303///estradiol 17-beta-dehydrogenase activity+++GO:1903924///estradiol binding+++GO:0070401///NADP+ binding","GO:0008210///estrogen metabolic process+++GO:0061370///testosterone biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0006629///lipid metabolic process+++GO:0006694///steroid biosynthetic process+++GO:0006703///estrogen biosynthetic process+++GO:0071248///cellular response to metal ion+++GO:0060348///bone development","hydroxysteroid 17-beta dehydrogenase 1","[DHB1_HUMAN|Reviewed]RecName: Full=Estradiol 17-beta-dehydrogenase 1; EC=1.1.1.62; AltName: Full=17-beta-hydroxysteroid dehydrogenase type 1; Short=17-beta-HSD 1; AltName: Full=20 alpha-hydroxysteroid dehydrogenase; Short=20-alpha-HSD; AltName: Full=E2DH; AltName: Full=Placental 17-beta-hydroxysteroid dehydrogenase; AltName: Full=Short chain dehydrogenase/reductase family 28C member 1;+++[A0A0A0MQS7_HUMAN|Unreviewed]SubName: Full=Estradiol 17-beta-dehydrogenase 1 {ECO:0000313|Ensembl:ENSP00000225929};+++[B4DU11_HUMAN|Unreviewed]SubName: Full=Estradiol 17-beta-dehydrogenase 1 {ECO:0000313|Ensembl:ENSP00000465128}; SubName: Full=cDNA FLJ50217, highly similar to Estradiol 17-beta-dehydrogenase 1 {ECO:0000313|EMBL:BAG62173.1};"]
[3303,"'HSPA1A'",4007.09,3485.24,3774.75,3755.69333333333,"05134///Legionellosis+++05162///Measles+++04213///Longevity regulating pathway - multiple species+++04010///MAPK signaling pathway+++04144///Endocytosis+++03040///Spliceosome+++04915///Estrogen signaling pathway+++05145///Toxoplasmosis+++04612///Antigen processing and presentation+++04141///Protein processing in endoplasmic reticulum+++05169///Epstein-Barr virus infection+++05164///Influenza A",null,"M00353///Spliceosome, Prp19/CDC5L complex+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016235///aggresome+++GO:0005576///extracellular region+++GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm+++GO:0005815///microtubule organizing center+++GO:0016607///nuclear speck+++GO:0016234///inclusion body+++GO:1904813///ficolin-1-rich granule lumen+++GO:0031982///vesicle+++GO:0072562///blood microparticle+++GO:0008180///COP9 signalosome+++GO:0005813///centrosome+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0032991///protein-containing complex+++GO:0005925///focal adhesion+++GO:1990904///ribonucleoprotein complex+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum","GO:0044183///protein binding involved in protein folding+++GO:0047485///protein N-terminus binding+++GO:0001664///G protein-coupled receptor binding+++GO:0016887///ATPase activity+++GO:0005515///protein binding+++GO:0051787///misfolded protein binding+++GO:0042623///ATPase activity, coupled+++GO:0031625///ubiquitin protein ligase binding+++GO:0019899///enzyme binding+++GO:0005102///signaling receptor binding+++GO:0051082///unfolded protein binding+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0001618///virus receptor activity+++GO:0097718///disordered domain specific binding+++GO:0003714///transcription corepressor activity+++GO:0031249///denatured protein binding+++GO:0045296///cadherin binding+++GO:0042826///histone deacetylase binding+++GO:0000166///nucleotide binding+++GO:0055131///C3HC4-type RING finger domain binding+++GO:0031072///heat shock protein binding","GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0046034///ATP metabolic process+++GO:1900034///regulation of cellular response to heat+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0070434///positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0006986///response to unfolded protein+++GO:0006402///mRNA catabolic process+++GO:1902380///positive regulation of endoribonuclease activity+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0070370///cellular heat acclimation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0010628///positive regulation of gene expression+++GO:1901673///regulation of mitotic spindle assembly+++GO:0050821///protein stabilization+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0031396///regulation of protein ubiquitination+++GO:0034620///cellular response to unfolded protein+++GO:0008285///negative regulation of cell proliferation+++GO:0046718///viral entry into host cell+++GO:0090084///negative regulation of inclusion body assembly+++GO:0033120///positive regulation of RNA splicing+++GO:0043312///neutrophil degranulation+++GO:0060548///negative regulation of cell death+++GO:0032757///positive regulation of interleukin-8 production+++GO:0043488///regulation of mRNA stability+++GO:0030308///negative regulation of cell growth+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0042026///protein refolding+++GO:0034599///cellular response to oxidative stress+++GO:0090063///positive regulation of microtubule nucleation+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034605///cellular response to heat+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0010941///regulation of cell death+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand","heat shock protein family A (Hsp70) member 1A","[HS71A_HUMAN|Reviewed]RecName: Full=Heat shock 70 kDa protein 1A {ECO:0000312|HGNC:HGNC:5232}; AltName: Full=Heat shock 70 kDa protein 1; Short=HSP70-1 {ECO:0000303|PubMed:14656967, ECO:0000303|PubMed:2538825}; Short=HSP70.1;+++[HS71B_HUMAN|Reviewed]RecName: Full=Heat shock 70 kDa protein 1B {ECO:0000312|HGNC:HGNC:5233}; AltName: Full=Heat shock 70 kDa protein 2; Short=HSP70-2 {ECO:0000303|PubMed:14656967, ECO:0000303|PubMed:2538825}; Short=HSP70.2;+++[A8K5I0_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 103 {ECO:0000313|EMBL:ACI45984.1}; SubName: Full=HSPA1A {ECO:0000313|EMBL:AQY76864.1}; SubName: Full=HSPA1B {ECO:0000313|EMBL:AQY76874.1}; SubName: Full=Heat shock 70kDa protein 1A {ECO:0000313|EMBL:EAX03528.1}; SubName: Full=Heat shock 70kDa protein 1B {ECO:0000313|EMBL:EAX03529.1}; SubName: Full=cDNA FLJ75127, highly similar to Homo sapiens heat shock 70kDa protein 1A, mRNA {ECO:0000313|EMBL:BAF83984.1};+++[B3KTT5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38698 fis, clone KIDNE2002015, highly similar to HEAT SHOCK 70 kDa PROTEIN 1 {ECO:0000313|EMBL:BAG53197.1};+++[Q9UQC1_HUMAN|Unreviewed]SubName: Full=Heat shock protein 72 {ECO:0000313|EMBL:BAA77235.1}; Flags: Fragment;+++[V9GZ37_HUMAN|Unreviewed]SubName: Full=Heat shock 70 kDa protein 1A {ECO:0000313|Ensembl:ENSP00000477378};"]
[333926,"'PPM1J'",9,13,9,10.3333333333333,{"$nulls":5},"GO:0016787///hydrolase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0003824///catalytic activity+++GO:0004721///phosphoprotein phosphatase activity","GO:0006470///protein dephosphorylation","protein phosphatase, Mg2+/Mn2+ dependent 1J","[PPM1J_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1J; EC=3.1.3.16; AltName: Full=Protein phosphatase 2C isoform zeta; Short=PP2C-zeta;+++[B5BU91_HUMAN|Unreviewed]SubName: Full=HCG1997303, isoform CRA_a {ECO:0000313|EMBL:EAW56541.1}; SubName: Full=Protein phosphatase 1J {ECO:0000313|EMBL:BAG70141.1};+++[L8E868_HUMAN|Unreviewed]SubName: Full=Alternative protein PPM1J {ECO:0000313|EMBL:CCQ43304.1};+++[S4R3C3_HUMAN|Unreviewed]SubName: Full=HCG1997303, isoform CRA_b {ECO:0000313|EMBL:EAW56542.1}; SubName: Full=Protein phosphatase 1J {ECO:0000313|Ensembl:ENSP00000474145};+++[S4R3I3_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1J {ECO:0000313|Ensembl:ENSP00000474405}; Flags: Fragment;"]
[3358,"'HTR2C'",16,9,9,11.3333333333333,"04726///Serotonergic synapse+++04750///Inflammatory mediator regulation of TRP channels+++04540///Gap junction+++04080///Neuroactive ligand-receptor interaction+++04020///Calcium signaling pathway","H01611///Alcohol dependence+++H01646///Major depressive disorder (MDD)+++H01450///Obsessive-compulsive disorder (OCD)+++H01649///Schizophrenia",null,null,"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030425///dendrite","GO:0051378///serotonin binding+++GO:0030594///neurotransmitter receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004993///G protein-coupled serotonin receptor activity+++GO:0008144///drug binding+++GO:0071886///1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding+++GO:0001587///Gq/11-coupled serotonin receptor activity","GO:0007210///serotonin receptor signaling pathway+++GO:0007208///phospholipase C-activating serotonin receptor signaling pathway+++GO:0006874///cellular calcium ion homeostasis+++GO:0045600///positive regulation of fat cell differentiation+++GO:0098664///G protein-coupled serotonin receptor signaling pathway+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0007631///feeding behavior+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0031644///regulation of neurological system process+++GO:0007268///chemical synaptic transmission+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007165///signal transduction+++GO:0007610///behavior+++GO:0007626///locomotory behavior+++GO:0001662///behavioral fear response+++GO:0042493///response to drug+++GO:0010513///positive regulation of phosphatidylinositol biosynthetic process+++GO:0019934///cGMP-mediated signaling+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043397///regulation of corticotropin-releasing hormone secretion+++GO:0032098///regulation of appetite+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","5-hydroxytryptamine receptor 2C","[5HT2C_HUMAN|Reviewed]RecName: Full=5-hydroxytryptamine receptor 2C; Short=5-HT-2C; Short=5-HT2C; Short=5-HTR2C; AltName: Full=5-hydroxytryptamine receptor 1C; Short=5-HT-1C; Short=5-HT1C; AltName: Full=Serotonin receptor 2C; Flags: Precursor;+++[B3VRE0_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96328.1}; Flags: Fragment;+++[B3VRE5_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96323.1}; Flags: Fragment;+++[B3VRF0_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96318.1}; Flags: Fragment;+++[B3VRF5_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine (Serotonin) receptor 2C {ECO:0000313|EMBL:ACE96313.1}; Flags: Fragment;+++[K9J958_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine receptor-1c variant {ECO:0000313|EMBL:ACO54890.1};+++[Q7Z579_HUMAN|Unreviewed]SubName: Full=5-hydroxytryptamine receptor 2C variant b {ECO:0000313|EMBL:AAM78371.1}; Flags: Fragment;"]
[337867,"'UBAC2'",650,662,762,691.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0070972///protein localization to endoplasmic reticulum+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol","UBA domain containing 2","[UBAC2_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated domain-containing protein 2; Short=UBA domain-containing protein 2; AltName: Full=Phosphoglycerate dehydrogenase-like protein 1; Flags: Precursor;+++[A0A024RE02_HUMAN|Unreviewed]SubName: Full=Phosphoglycerate dehydrogenase like 1, isoform CRA_c {ECO:0000313|EMBL:EAX09015.1};+++[A0A087WXT1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000481260}; Flags: Fragment;+++[A8K2S7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77865 {ECO:0000313|EMBL:BAF83031.1};+++[B3KW74_HUMAN|Unreviewed]SubName: Full=Phosphoglycerate dehydrogenase like 1, isoform CRA_e {ECO:0000313|EMBL:EAX09014.1}; SubName: Full=cDNA FLJ42413 fis, clone BLADE2001141, moderately similar to Mus musculus ubiquitin associated domain containing 2 (Ubac2), mRNA {ECO:0000313|EMBL:BAG54036.1};+++[Q5JUH4_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000402249}; Flags: Fragment;+++[X6R5E5_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000347928}; Flags: Fragment;"]
[338773,"'TMEM119'",1,3,9,4.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0003674///molecular_function","GO:1903012///positive regulation of bone development+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0001503///ossification+++GO:0030501///positive regulation of bone mineralization+++GO:0048515///spermatid differentiation+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0031214///biomineral tissue development+++GO:0001649///osteoblast differentiation","transmembrane protein 119","[TM119_HUMAN|Reviewed]RecName: Full=Transmembrane protein 119; AltName: Full=Osteoblast induction factor; Short=OBIF; Flags: Precursor;+++[F8VS22_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 119 {ECO:0000313|Ensembl:ENSP00000448583}; Flags: Fragment;+++[F8VZL0_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 119 {ECO:0000313|Ensembl:ENSP00000447345}; Flags: Fragment;+++[F8W0W9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 119 {ECO:0000313|Ensembl:ENSP00000447120}; Flags: Fragment;"]
[339184,"'CCDC144NL'",4,1,3,2.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0003964///RNA-directed DNA polymerase activity",null,"coiled-coil domain containing 144 family, N-terminal like","[C144L_HUMAN|Reviewed]RecName: Full=Putative coiled-coil domain-containing protein 144 N-terminal-like;"]
[339559,"'ZFP69'",48,23,34,35,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006629///lipid metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0019216///regulation of lipid metabolic process","ZFP69 zinc finger protein","[ZFP69_HUMAN|Reviewed]RecName: Full=Zinc finger protein 69 homolog {ECO:0000250|UniProtKB:A2A761}; AltName: Full=Zinc finger protein 642;"]
[339804,"'C2orf74'",107,125,101,111,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"chromosome 2 open reading frame 74","[CB074_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C2orf74;+++[A0A087WXS6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf74 {ECO:0000313|Ensembl:ENSP00000481253}; Flags: Fragment;+++[A0A087X1C3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf74 {ECO:0000313|Ensembl:ENSP00000484061};+++[C9JBF1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf74 {ECO:0000313|Ensembl:ENSP00000398725};+++[F8VY72_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf74 {ECO:0000313|Ensembl:ENSP00000381621};"]
[340277,"'FAM221A'",90,56,87,77.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0030144///alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity","GO:0006487///protein N-linked glycosylation","family with sequence similarity 221 member A","[F221A_HUMAN|Reviewed]RecName: Full=Protein FAM221A;+++[A0A024RA57_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW93799.1};+++[B8ZZQ8_HUMAN|Unreviewed]SubName: Full=Protein FAM221A {ECO:0000313|Ensembl:ENSP00000386900};+++[F8WCP2_HUMAN|Unreviewed]SubName: Full=Protein FAM221A {ECO:0000313|Ensembl:ENSP00000404551};+++[F8WCP3_HUMAN|Unreviewed]SubName: Full=Protein FAM221A {ECO:0000313|Ensembl:ENSP00000416525};"]
[340526,"'RTL5'",588,573,438,533,{"$nulls":7},"retrotransposon Gag like 5","[RTL5_HUMAN|Reviewed]RecName: Full=Retrotransposon Gag-like protein 5 {ECO:0000312|HGNC:HGNC:29430}; AltName: Full=Retrotransposon gag domain-containing protein 4 {ECO:0000305};"]
[341346,"'SMCO2'",1.99,1,4,2.33,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"single-pass membrane protein with coiled-coil domains 2","[SMCO2_HUMAN|Reviewed]RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 2;+++[J3KNC3_HUMAN|Unreviewed]SubName: Full=Single-pass membrane and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000298876};"]
[3420,"'IDH3B'",518,588,610,572,"00020///Citrate cycle (TCA cycle)+++01120///Microbial metabolism in diverse environments+++01230///Biosynthesis of amino acids+++01110///Biosynthesis of secondary metabolites+++01210///2-Oxocarboxylic acid metabolism+++01200///Carbon metabolism+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways","H00527///Retinitis pigmentosa (RP)","M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00010///Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate","R00709///isocitrate:NAD+ oxidoreductase (decarboxylating)   Isocitrate + NAD+ <=> 2-Oxoglutarate + CO2 + NADH + H+","GO:0005634///nucleus+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0051287///NAD binding+++GO:0009055///electron transfer activity+++GO:0000287///magnesium ion binding+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0004449///isocitrate dehydrogenase (NAD+) activity","GO:0055114///oxidation-reduction process+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006102///isocitrate metabolic process+++GO:0022900///electron transport chain+++GO:0006734///NADH metabolic process","isocitrate dehydrogenase 3 (NAD(+)) beta","[IDH3B_HUMAN|Reviewed]RecName: Full=Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial; AltName: Full=Isocitric dehydrogenase subunit beta; AltName: Full=NAD(+)-specific ICDH subunit beta; Flags: Precursor;+++[A0A087WZN1_HUMAN|Unreviewed]RecName: Full=Isocitrate dehydrogenase [NAD] subunit, mitochondrial {ECO:0000256|RuleBase:RU361266};+++[A0A087X2E5_HUMAN|Unreviewed]RecName: Full=Isocitrate dehydrogenase [NAD] subunit, mitochondrial {ECO:0000256|RuleBase:RU361266};+++[A0A0D9SET9_HUMAN|Unreviewed]SubName: Full=Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000485997}; Flags: Fragment;+++[A0A0D9SG66_HUMAN|Unreviewed]SubName: Full=Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial {ECO:0000313|Ensembl:ENSP00000487187}; Flags: Fragment;+++[L0R875_HUMAN|Unreviewed]SubName: Full=Alternative protein IDH3B {ECO:0000313|EMBL:CCO13746.1};"]
[342897,"'NCCRP1'",402,128,214,248,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04141///Protein processing in endoplasmic reticulum",null,"M00382///SCF-FBS complex",null,"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm",null,"GO:0008284///positive regulation of cell proliferation","non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)","[FBX50_HUMAN|Reviewed]RecName: Full=F-box only protein 50; AltName: Full=NCC receptor protein 1 homolog; Short=NCCRP-1; AltName: Full=Non-specific cytotoxic cell receptor protein 1 homolog;"]
[343066,"'AADACL4'",340,159,191,230,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0052689///carboxylic ester hydrolase activity+++GO:0016787///hydrolase activity","GO:0009056///catabolic process","arylacetamide deacetylase like 4","[ADCL4_HUMAN|Reviewed]RecName: Full=Arylacetamide deacetylase-like 4; EC=3.1.1.-;+++[L8E711_HUMAN|Unreviewed]SubName: Full=Alternative protein AADACL4 {ECO:0000313|EMBL:CCQ43035.1};"]
[344657,"'LRRIQ4'",1,0,5,2,{"$nulls":4},"GO:0034702///ion channel complex+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0005225///volume-sensitive anion channel activity","GO:0007165///signal transduction+++GO:0098656///anion transmembrane transport","leucine rich repeats and IQ motif containing 4","[LRIQ4_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat and IQ domain-containing protein 4; AltName: Full=Leucine-rich repeat-containing protein 64;"]
[345557,"'PLCXD3'",2,1,2,1.66666666666667,{"$nulls":4},"GO:0005737///cytoplasm","GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity","GO:0016042///lipid catabolic process+++GO:0007165///signal transduction+++GO:0006629///lipid metabolic process","phosphatidylinositol specific phospholipase C X domain containing 3","[PLCX3_HUMAN|Reviewed]RecName: Full=PI-PLC X domain-containing protein 3;+++[B3KXD1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45199 fis, clone BRCAN2003814, highly similar to Homo sapiens phosphatidylinositol-specific phospholipase C, X domain containing 3 (PLCXD3), mRNA {ECO:0000313|EMBL:BAG54443.1};"]
[346606,"'MOGAT3'",0,0,1,0.333333333333333,"00561///Glycerolipid metabolism+++01100///Metabolic pathways+++04975///Fat digestion and absorption",null,"M00089///Triacylglycerol biosynthesis","R03755///acyl-CoA:2-acylglycerol O-acyltransferase   Acyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol+++R02251///acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase   Triacylglycerol + CoA <=> 1,2-Diacyl-sn-glycerol + Acyl-CoA+++R03756///2,3-dehydroacyl-CoA:2-acylglycerol O-acyltransferase   2,3-Dehydroacyl-CoA + 1-Acylglycerol <=> CoA + 1,2-Diacyl-sn-glycerol","GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:1990578///perinuclear endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0004144///diacylglycerol O-acyltransferase activity+++GO:0003830///beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0003846///2-acylglycerol O-acyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016746///transferase activity, transferring acyl groups","GO:0006044///N-acetylglucosamine metabolic process+++GO:0030334///regulation of cell migration+++GO:0034599///cellular response to oxidative stress+++GO:0019432///triglyceride biosynthetic process+++GO:0050435///amyloid-beta metabolic process+++GO:0006071///glycerol metabolic process+++GO:1905166///negative regulation of lysosomal protein catabolic process+++GO:0006629///lipid metabolic process+++GO:1902966///positive regulation of protein localization to early endosome+++GO:0006487///protein N-linked glycosylation+++GO:0050890///cognition+++GO:0006486///protein glycosylation+++GO:0008104///protein localization","monoacylglycerol O-acyltransferase 3","[MOGT3_HUMAN|Reviewed]RecName: Full=2-acylglycerol O-acyltransferase 3; EC=2.3.1.20; EC=2.3.1.22; AltName: Full=Acyl-CoA:monoacylglycerol acyltransferase 3; Short=MGAT3; AltName: Full=Diacylglycerol O-acyltransferase candidate 7; Short=hDC7; AltName: Full=Diacylglycerol acyltransferase 2-like protein 7; AltName: Full=Monoacylglycerol O-acyltransferase 3;+++[B0QY92_HUMAN|Unreviewed]SubName: Full=Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase {ECO:0000313|Ensembl:ENSP00000408075}; Flags: Fragment;+++[B0QY93_HUMAN|Unreviewed]SubName: Full=Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase {ECO:0000313|Ensembl:ENSP00000416226}; Flags: Fragment;"]
[347688,"'TUBB8'",2.74,0,0,0.913333333333333,"04540///Gap junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H00271///Polymicrogyria+++H01579///Congenital symmetric circumferential skin creases+++H01881///Complex cortical dysplasia with other brain malformations+++H01740///Macrothrombocytopenia+++H01897///Oocyte maturation defect+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H00679///Hypomyelinating leukodystrophy",null,null,"GO:0005737///cytoplasm+++GO:0072687///meiotic spindle+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070062///extracellular exosome","GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0003674///molecular_function+++GO:0005200///structural constituent of cytoskeleton+++GO:0005525///GTP binding","GO:0007017///microtubule-based process+++GO:0001556///oocyte maturation+++GO:0000226///microtubule cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0007056///spindle assembly involved in female meiosis","tubulin beta 8 class VIII","[TBB8_HUMAN|Reviewed]RecName: Full=Tubulin beta-8 chain {ECO:0000305}; AltName: Full=Tubulin beta 8 class VIII {ECO:0000312|HGNC:HGNC:20773};+++[A0A075B724_HUMAN|Unreviewed]SubName: Full=Tubulin beta-8 chain {ECO:0000313|Ensembl:ENSP00000454878};+++[A0A075B725_HUMAN|Unreviewed]SubName: Full=Tubulin beta-8 chain {ECO:0000313|Ensembl:ENSP00000454914};+++[A0A075B735_HUMAN|Unreviewed]SubName: Full=Tubulin beta-8 chain {ECO:0000313|Ensembl:ENSP00000456899};+++[A0A075B736_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q5SQY0_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};"]
[347730,"'LRRTM1'",7,4,6,5.66666666666667,{"$nulls":4},"GO:0030424///axon+++GO:0005886///plasma membrane+++GO:0031012///extracellular matrix+++GO:0099055///integral component of postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0045202///synapse+++GO:0030426///growth cone+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0045211///postsynaptic membrane+++GO:0030054///cell junction+++GO:0009986///cell surface+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse","GO:0003674///molecular_function","GO:0002091///negative regulation of receptor internalization+++GO:0050808///synapse organization+++GO:1905606///regulation of presynapse assembly+++GO:0008150///biological_process+++GO:0099151///regulation of postsynaptic density assembly+++GO:0007626///locomotory behavior+++GO:0035418///protein localization to synapse+++GO:0035640///exploration behavior+++GO:0060291///long-term synaptic potentiation+++GO:0051965///positive regulation of synapse assembly","leucine rich repeat transmembrane neuronal 1","[LRRT1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat transmembrane neuronal protein 1; Flags: Precursor;+++[C9JEE2_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat transmembrane neuronal protein 1 {ECO:0000313|Ensembl:ENSP00000415368}; Flags: Fragment;+++[C9JF97_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat transmembrane neuronal protein 1 {ECO:0000313|Ensembl:ENSP00000404557}; Flags: Fragment;+++[C9JPM9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat transmembrane neuronal protein 1 {ECO:0000313|Ensembl:ENSP00000389473}; Flags: Fragment;"]
[3481,"'IGF2'",102,363,374,279.666666666667,"05200///Pathways in cancer+++04010///MAPK signaling pathway+++05225///Hepatocellular carcinoma+++04151///PI3K-Akt signaling pathway+++05205///Proteoglycans in cancer+++04014///Ras signaling pathway","H00033///Adrenal carcinoma+++H00048///Hepatocellular carcinoma+++H00711///Russell-Silver syndrome+++H00713///Beckwith-Wiedemann syndrome",null,null,"GO:0005576///extracellular region+++GO:0031093///platelet alpha granule lumen+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0008083///growth factor activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0005159///insulin-like growth factor receptor binding+++GO:0005179///hormone activity+++GO:0005158///insulin receptor binding+++GO:0048018///receptor ligand activity","GO:0001503///ossification+++GO:0040018///positive regulation of multicellular organism growth+++GO:0002576///platelet degranulation+++GO:0001649///osteoblast differentiation+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0031017///exocrine pancreas development+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0044267///cellular protein metabolic process+++GO:0008286///insulin receptor signaling pathway+++GO:0051781///positive regulation of cell division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051146///striated muscle cell differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0060669///embryonic placenta morphogenesis+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007275///multicellular organism development+++GO:0006006///glucose metabolic process+++GO:0001701///in utero embryonic development+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0009887///animal organ morphogenesis+++GO:0001501///skeletal system development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000467///positive regulation of glycogen (starch) synthase activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0001892///embryonic placenta development+++GO:0008284///positive regulation of cell proliferation+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0031056///regulation of histone modification+++GO:0043085///positive regulation of catalytic activity+++GO:0051147///regulation of muscle cell differentiation+++GO:0010469///regulation of signaling receptor activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0005975///carbohydrate metabolic process","insulin like growth factor 2","[IGF2_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor II; Short=IGF-II; AltName: Full=Somatomedin-A; AltName: Full=T3M-11-derived growth factor; Contains: RecName: Full=Insulin-like growth factor II; Contains: RecName: Full=Insulin-like growth factor II Ala-25 Del; Contains: RecName: Full=Preptin; Flags: Precursor;+++[A0A024RCE6_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 (Somatomedin A), isoform CRA_a {ECO:0000313|EMBL:EAX02486.1};+++[A0A2R8Y747_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor II {ECO:0000313|Ensembl:ENSP00000495715};+++[B2MUX6_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 {ECO:0000313|EMBL:ACC95538.1};+++[E3UN46_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor II transcript variant 3 isoform 1 {ECO:0000313|EMBL:ADO21455.1}; Flags: Fragment;"]
[348793,"'WDR53'",75,65,57,65.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","WD repeat domain 53","[WDR53_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 53;+++[C9JBE7_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 53 {ECO:0000313|Ensembl:ENSP00000410677};+++[C9JDR5_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 53 {ECO:0000313|Ensembl:ENSP00000396248}; Flags: Fragment;+++[C9JJZ8_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 53 {ECO:0000313|Ensembl:ENSP00000396668};+++[C9JQN1_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 53 {ECO:0000313|Ensembl:ENSP00000408087}; Flags: Fragment;"]
[35,"'ACADS'",97,102,117,105.333333333333,"00280///Valine, leucine and isoleucine degradation+++00071///Fatty acid degradation+++00650///Butanoate metabolism+++01110///Biosynthesis of secondary metabolites+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways","H00525///Disorders of mitochondrial fatty-acid oxidation+++H01980///SCAD deficiency",null,"R01175///butanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA+++R03172///(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase   (S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor+++R02661///2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase   2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor+++R04751///hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2+++R01178///short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein","GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion","GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016491///oxidoreductase activity+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004085///butyryl-CoA dehydrogenase activity+++GO:0050660///flavin adenine dinucleotide binding","GO:0046359///butyrate catabolic process+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0055114///oxidation-reduction process+++GO:0006631///fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006635///fatty acid beta-oxidation","acyl-CoA dehydrogenase short chain","[ACADS_HUMAN|Reviewed]RecName: Full=Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Short=SCAD; EC=1.3.8.1; AltName: Full=Butyryl-CoA dehydrogenase; Flags: Precursor;+++[B4DUH1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51323, highly similar to Short-chain specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000313|EMBL:BAG62333.1};+++[D4QEZ8_HUMAN|Unreviewed]SubName: Full=Short-chain acyl-CoA dehydrogenase {ECO:0000313|EMBL:BAJ05798.1};+++[E5KSD5_HUMAN|Unreviewed]SubName: Full=Acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain {ECO:0000313|EMBL:EAW98218.1}; SubName: Full=Mitochondrial short-chain specific acyl-CoA dehydrogenase {ECO:0000313|EMBL:ADP91814.1};+++[E9PE82_HUMAN|Unreviewed]SubName: Full=Short-chain-specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000401045};"]
[353322,"'ANKRD37'",99,68,77,81.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01817///Beukes hip dysplasia (BHD)",null,null,"GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016790///thiolester hydrolase activity+++GO:0071567///UFM1 hydrolase activity","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0006508///proteolysis","ankyrin repeat domain 37","[ANR37_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 37; AltName: Full=Low-density lipoprotein receptor-related protein 2-binding protein; Short=hLrp2bp;+++[B4E066_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50037, highly similar to Ankyrin repeat domain-containing protein 37 {ECO:0000313|EMBL:BAG64328.1};+++[D6RFF5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 37 {ECO:0000313|Ensembl:ENSP00000421529}; Flags: Fragment;"]
[3556,"'IL1RAP'",233.26,327.86,254,271.706666666667,"04750///Inflammatory mediator regulation of TRP channels+++04659///Th17 cell differentiation+++04060///Cytokine-cytokine receptor interaction+++04010///MAPK signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region","GO:0002114///interleukin-33 receptor activity+++GO:0004908///interleukin-1 receptor activity","GO:2000778///positive regulation of interleukin-6 secretion+++GO:0072602///interleukin-4 secretion+++GO:0019221///cytokine-mediated signaling pathway+++GO:0065003///protein-containing complex assembly+++GO:0006954///inflammatory response+++GO:0099151///regulation of postsynaptic density assembly+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0045087///innate immune response+++GO:0032754///positive regulation of interleukin-5 production+++GO:0007165///signal transduction+++GO:0002376///immune system process+++GO:0032736///positive regulation of interleukin-13 production+++GO:0051965///positive regulation of synapse assembly+++GO:0006955///immune response+++GO:0038172///interleukin-33-mediated signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0099545///trans-synaptic signaling by trans-synaptic complex+++GO:1905606///regulation of presynapse assembly+++GO:0042094///interleukin-2 biosynthetic process+++GO:0099560///synaptic membrane adhesion","interleukin 1 receptor accessory protein","[IL1AP_HUMAN|Reviewed]RecName: Full=Interleukin-1 receptor accessory protein; Short=IL-1 receptor accessory protein; Short=IL-1RAcP; AltName: Full=Interleukin-1 receptor 3; Short=IL-1R-3; Short=IL-1R3; Flags: Precursor;+++[A8K6K4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77565, highly similar to Homo sapiens interleukin 1 receptor accessory protein (IL1RAP), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84358.1};+++[C9J1D9_HUMAN|Unreviewed]SubName: Full=Interleukin-1 receptor accessory protein {ECO:0000313|Ensembl:ENSP00000412008}; Flags: Fragment;+++[C9J9W1_HUMAN|Unreviewed]SubName: Full=Interleukin-1 receptor accessory protein {ECO:0000313|Ensembl:ENSP00000391899};+++[C9JT28_HUMAN|Unreviewed]SubName: Full=Interleukin-1 receptor accessory protein {ECO:0000313|Ensembl:ENSP00000389149}; Flags: Fragment;+++[H7C3W4_HUMAN|Unreviewed]SubName: Full=Interleukin-1 receptor accessory protein {ECO:0000313|Ensembl:ENSP00000414102}; Flags: Fragment;"]
[3590,"'IL11RA'",190,216,243,216.333333333333,"04640///Hematopoietic cell lineage+++04060///Cytokine-cytokine receptor interaction+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0009897///external side of plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity+++GO:0019955///cytokine binding+++GO:0019970///interleukin-11 binding+++GO:0004921///interleukin-11 receptor activity","GO:0008284///positive regulation of cell proliferation+++GO:0038154///interleukin-11-mediated signaling pathway+++GO:0060322///head development+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032502///developmental process","interleukin 11 receptor subunit alpha","[I11RA_HUMAN|Reviewed]RecName: Full=Interleukin-11 receptor subunit alpha; Short=IL-11 receptor subunit alpha; Short=IL-11R subunit alpha; Short=IL-11R-alpha; Short=IL-11RA; Flags: Precursor;+++[G3V2A5_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000450543}; Flags: Fragment;+++[G3V2G0_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000450640}; Flags: Fragment;+++[G3V2J5_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000450707};+++[G3V3V2_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000451447}; Flags: Fragment;+++[G3V428_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000451553};+++[G3V571_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000452207}; Flags: Fragment;+++[H0YCS8_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000432263}; Flags: Fragment;+++[Q5VZ79_HUMAN|Unreviewed]SubName: Full=HCG2011440, isoform CRA_a {ECO:0000313|EMBL:EAW58422.1}; SubName: Full=cDNA FLJ37370 fis, clone BRAMY2024593, highly similar to Interleukin-11 receptor alpha chain {ECO:0000313|EMBL:BAG52913.1}; SubName: Full=cDNA FLJ78258, highly similar to Homo sapiens interleukin 11 receptor, alpha (IL11RA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84762.1};"]
[3601,"'IL15RA'",19,21,15,18.3333333333333,"04060///Cytokine-cytokine receptor interaction+++05200///Pathways in cancer+++04630///Jak-STAT signaling pathway+++04672///Intestinal immune network for IgA production+++05166///HTLV-I infection",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005768///endosome+++GO:0031965///nuclear membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0031410///cytoplasmic vesicle+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0004896///cytokine receptor activity","GO:0008283///cell proliferation+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0007165///signal transduction","interleukin 15 receptor subunit alpha","[I15RA_HUMAN|Reviewed]RecName: Full=Interleukin-15 receptor subunit alpha; Short=IL-15 receptor subunit alpha; Short=IL-15R-alpha; Short=IL-15RA; AltName: CD_antigen=CD215; Contains: RecName: Full=Soluble interleukin-15 receptor subunit alpha; Short=sIL-15 receptor subunit alpha; Short=sIL-15R-alpha; Short=sIL-15RA; Flags: Precursor;+++[A0A0A0MS77_HUMAN|Unreviewed]SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000380421};+++[E7ETI1_HUMAN|Unreviewed]SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000380420}; Flags: Fragment;+++[E9PQ64_HUMAN|Unreviewed]SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000395113}; Flags: Fragment;+++[G8CVM3_HUMAN|Unreviewed]SubName: Full=Interleukin 15 receptor alpha {ECO:0000313|EMBL:AEP26933.1};+++[H0Y4R3_HUMAN|Unreviewed]SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000393612}; Flags: Fragment;+++[H0Y6E8_HUMAN|Unreviewed]SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000405128}; Flags: Fragment;+++[H0YD11_HUMAN|Unreviewed]SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000432691}; Flags: Fragment;+++[K9N163_HUMAN|Unreviewed]SubName: Full=Interleukin 15 receptor alpha isoform IC2 {ECO:0000313|EMBL:AFY11388.1}; SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000479839};+++[K9N1J3_HUMAN|Unreviewed]SubName: Full=Interleukin 15 receptor alpha isoform IC5 {ECO:0000313|EMBL:AFY11391.1}; SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000380423};+++[K9N2Q6_HUMAN|Unreviewed]SubName: Full=Interleukin 15 receptor alpha isoform IC3 {ECO:0000313|EMBL:AFY11389.1}; SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000480949};+++[K9N2S2_HUMAN|Unreviewed]SubName: Full=Interleukin 15 receptor alpha isoform EM2 {ECO:0000313|EMBL:AFY11387.1}; SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000478525};+++[Q5JVA3_HUMAN|Unreviewed]SubName: Full=Interleukin-15 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000405107}; Flags: Fragment;+++[Q6P0Q3_HUMAN|Unreviewed]SubName: Full=IL15RA protein {ECO:0000313|EMBL:AAH65506.1};"]
[3622,"'ING2'",127,124,141,130.666666666667,{"$nulls":4},"GO:0016580///Sin3 complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016602///CCAAT-binding factor complex+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane","GO:0044877///protein-containing complex binding+++GO:0035064///methylated histone binding+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0035091///phosphatidylinositol binding","GO:0007141///male meiosis I+++GO:0007165///signal transduction+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0072520///seminiferous tubule development+++GO:0007286///spermatid development+++GO:2000772///regulation of cellular senescence+++GO:0006325///chromatin organization+++GO:0030317///flagellated sperm motility+++GO:0048133///male germ-line stem cell asymmetric division+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0006351///transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0031065///positive regulation of histone deacetylation+++GO:0040008///regulation of growth+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0008285///negative regulation of cell proliferation+++GO:0007283///spermatogenesis","inhibitor of growth family member 2","[ING2_HUMAN|Reviewed]RecName: Full=Inhibitor of growth protein 2; AltName: Full=Inhibitor of growth 1-like protein; Short=ING1Lp; AltName: Full=p32; AltName: Full=p33ING2;+++[B2RA15_HUMAN|Unreviewed]RecName: Full=Inhibitor of growth protein {ECO:0000256|RuleBase:RU361213};"]
[3635,"'INPP5D'",1394,1725,1375,1498,"00562///Inositol phosphate metabolism+++04662///B cell receptor signaling pathway+++04070///Phosphatidylinositol signaling system+++04664///Fc epsilon RI signaling pathway+++04666///Fc gamma R-mediated phagocytosis",null,null,"R09827///1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase   Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + Orthophosphate","GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0016314///phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0034485///phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity+++GO:0052659///inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity+++GO:0017124///SH3 domain binding+++GO:0004445///inositol-polyphosphate 5-phosphatase activity","GO:0006796///phosphate-containing compound metabolic process+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0045656///negative regulation of monocyte differentiation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0035556///intracellular signal transduction+++GO:0009968///negative regulation of signal transduction+++GO:0008340///determination of adult lifespan+++GO:0050900///leukocyte migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006915///apoptotic process+++GO:0050869///negative regulation of B cell activation+++GO:0016064///immunoglobulin mediated immune response+++GO:0050777///negative regulation of immune response+++GO:0045779///negative regulation of bone resorption+++GO:0043065///positive regulation of apoptotic process+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0045659///negative regulation of neutrophil differentiation+++GO:0030889///negative regulation of B cell proliferation+++GO:0045621///positive regulation of lymphocyte differentiation+++GO:0043647///inositol phosphate metabolic process+++GO:0045409///negative regulation of interleukin-6 biosynthetic process+++GO:0002376///immune system process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0045579///positive regulation of B cell differentiation+++GO:0030853///negative regulation of granulocyte differentiation+++GO:0050852///T cell receptor signaling pathway+++GO:0007165///signal transduction","inositol polyphosphate-5-phosphatase D","[SHIP1_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; EC=3.1.3.86; AltName: Full=Inositol polyphosphate-5-phosphatase of 145 kDa; Short=SIP-145; AltName: Full=SH2 domain-containing inositol 5'-phosphatase 1; Short=SH2 domain-containing inositol phosphatase 1; Short=SHIP-1; AltName: Full=p150Ship; Short=hp51CN;+++[H0Y5Q9_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 {ECO:0000313|Ensembl:ENSP00000397421}; Flags: Fragment;+++[H7C403_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 {ECO:0000313|Ensembl:ENSP00000414835}; Flags: Fragment;+++[R4GMN8_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 {ECO:0000313|Ensembl:ENSP00000473280}; Flags: Fragment;"]
[367,"'AR'",39,54,44,45.6666666666667,"05200///Pathways in cancer+++04114///Oocyte meiosis+++05215///Prostate cancer","H00024///Prostate cancer+++H00455///Spinal muscular atrophy (SMA)+++H00609///46,XY disorders of sex development (Other)+++H00608///46,XY disorders of sex development (Disorders in androgen synthesis or action)+++H00062///Spinal and bulbar muscular atrophy (SBMA)",null,null,"GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm","GO:0003677///DNA binding+++GO:0004882///androgen receptor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0004879///nuclear receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0070974///POU domain binding+++GO:0005102///signaling receptor binding+++GO:0046983///protein dimerization activity+++GO:0005496///steroid binding+++GO:0008013///beta-catenin binding+++GO:0003682///chromatin binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding+++GO:0051117///ATPase binding+++GO:0019899///enzyme binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005497///androgen binding+++GO:0043565///sequence-specific DNA binding","GO:1903076///regulation of protein localization to plasma membrane+++GO:0042327///positive regulation of phosphorylation+++GO:0048638///regulation of developmental growth+++GO:0072520///seminiferous tubule development+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:0030521///androgen receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030850///prostate gland development+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0033327///Leydig cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0008283///cell proliferation+++GO:0045720///negative regulation of integrin biosynthetic process+++GO:0045597///positive regulation of cell differentiation+++GO:0016579///protein deubiquitination+++GO:0060749///mammary gland alveolus development+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0060571///morphogenesis of an epithelial fold+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0048808///male genitalia morphogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0060520///activation of prostate induction by androgen receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0045726///positive regulation of integrin biosynthetic process+++GO:0007165///signal transduction+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0003382///epithelial cell morphogenesis+++GO:0048645///animal organ formation+++GO:0035264///multicellular organism growth+++GO:0007548///sex differentiation+++GO:0060599///lateral sprouting involved in mammary gland duct morphogenesis+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043410///positive regulation of MAPK cascade+++GO:0007338///single fertilization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001701///in utero embryonic development+++GO:0060736///prostate gland growth+++GO:0007283///spermatogenesis+++GO:0050790///regulation of catalytic activity+++GO:0019102///male somatic sex determination+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0071394///cellular response to testosterone stimulus+++GO:0051259///protein complex oligomerization+++GO:0060769///positive regulation of epithelial cell proliferation involved in prostate gland development+++GO:0008284///positive regulation of cell proliferation+++GO:0007267///cell-cell signaling","androgen receptor","[ANDR_HUMAN|Reviewed]RecName: Full=Androgen receptor; AltName: Full=Dihydrotestosterone receptor; AltName: Full=Nuclear receptor subfamily 3 group C member 4;+++[A0A087WUX9_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|Ensembl:ENSP00000479013};+++[F1D8N5_HUMAN|Unreviewed]SubName: Full=Androgen nuclear receptor variant 2 {ECO:0000313|EMBL:ADZ17334.1};+++[G4VV16_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform 8 {ECO:0000313|EMBL:ADK91081.1};+++[Q9NUA2_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|EMBL:AAK09424.1}; Flags: Fragment;"]
[368,"'ABCC6'",231,211,206,216,"02010///ABC transporters","H01002///Generalized arterial calcification of infancy+++H00560///Pseudoxanthoma elasticum",null,null,"GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005774///vacuolar membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0016323///basolateral plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0022857///transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0005524///ATP binding+++GO:0005215///transporter activity","GO:0055085///transmembrane transport+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0007601///visual perception+++GO:0042493///response to drug+++GO:0050896///response to stimulus","ATP binding cassette subfamily C member 6","[MRP6_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 6; AltName: Full=ATP-binding cassette sub-family C member 6; AltName: Full=Anthracycline resistance-associated protein; AltName: Full=Multi-specific organic anion transporter E; Short=MOAT-E;+++[A0A0G2JMG3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 6 {ECO:0000313|Ensembl:ENSP00000479163};+++[A0A0J9YVW5_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 6 {ECO:0000313|Ensembl:ENSP00000487705};+++[A0A1W2PPQ8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 6 {ECO:0000313|Ensembl:ENSP00000491278};+++[A0A1W2PQX7_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 6 {ECO:0000313|Ensembl:ENSP00000492197};+++[I3L1Z6_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 6 {ECO:0000313|Ensembl:ENSP00000459243};"]
[3707,"'ITPKB'",2785,2251,2044,2360,"01100///Metabolic pathways+++00562///Inositol phosphate metabolism+++04020///Calcium signaling pathway+++04070///Phosphatidylinositol signaling system",null,"M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R03433///ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase   ATP + D-myo-Inositol 1,4,5-trisphosphate <=> ADP + 1D-myo-Inositol 1,3,4,5-tetrakisphosphate","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0008440///inositol-1,4,5-trisphosphate 3-kinase activity+++GO:0005516///calmodulin binding+++GO:0000166///nucleotide binding","GO:0007166///cell surface receptor signaling pathway+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0007165///signal transduction+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0035726///common myeloid progenitor cell proliferation+++GO:0071277///cellular response to calcium ion+++GO:0043647///inositol phosphate metabolic process+++GO:0032957///inositol trisphosphate metabolic process+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0002262///myeloid cell homeostasis+++GO:0000165///MAPK cascade+++GO:0033030///negative regulation of neutrophil apoptotic process+++GO:0001932///regulation of protein phosphorylation+++GO:0045059///positive thymic T cell selection+++GO:0016310///phosphorylation+++GO:0030217///T cell differentiation+++GO:0045061///thymic T cell selection","inositol-trisphosphate 3-kinase B","[IP3KB_HUMAN|Reviewed]RecName: Full=Inositol-trisphosphate 3-kinase B; EC=2.7.1.127; AltName: Full=Inositol 1,4,5-trisphosphate 3-kinase B; Short=IP3 3-kinase B; Short=IP3K B; Short=InsP 3-kinase B;+++[B2R9J0_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[Q2TU82_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};"]
[3718,"'JAK3'",76,76.01,84,78.67,"05166///HTLV-I infection+++04062///Chemokine signaling pathway+++04630///Jak-STAT signaling pathway+++04217///Necroptosis+++04658///Th1 and Th2 cell differentiation+++05223///Non-small cell lung cancer+++05200///Pathways in cancer+++05169///Epstein-Barr virus infection+++04550///Signaling pathways regulating pluripotency of stem cells+++05162///Measles+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++04659///Th17 cell differentiation","H00091///T-B+Severe combined immunodeficiencies (SCIDs)","M00684///JAK-STAT signaling",null,"GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system","GO:0005524///ATP binding+++GO:0019903///protein phosphatase binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0004713///protein tyrosine kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0043029///T cell homeostasis+++GO:0035723///interleukin-15-mediated signaling pathway+++GO:0070669///response to interleukin-2+++GO:0046425///regulation of JAK-STAT cascade+++GO:0002376///immune system process+++GO:0042102///positive regulation of T cell proliferation+++GO:0038110///interleukin-2-mediated signaling pathway+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0002250///adaptive immune response+++GO:0045087///innate immune response+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0000165///MAPK cascade+++GO:0050868///negative regulation of T cell activation+++GO:0038114///interleukin-21-mediated signaling pathway+++GO:0070672///response to interleukin-15+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0032695///negative regulation of interleukin-12 production+++GO:0035556///intracellular signal transduction+++GO:0045626///negative regulation of T-helper 1 cell differentiation+++GO:0070670///response to interleukin-4+++GO:0035771///interleukin-4-mediated signaling pathway+++GO:0007260///tyrosine phosphorylation of STAT protein+++GO:0002731///negative regulation of dendritic cell cytokine production+++GO:0016310///phosphorylation+++GO:0030218///erythrocyte differentiation+++GO:0071104///response to interleukin-9+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0006468///protein phosphorylation+++GO:0070232///regulation of T cell apoptotic process+++GO:0060397///JAK-STAT cascade involved in growth hormone signaling pathway+++GO:0032693///negative regulation of interleukin-10 production+++GO:0045221///negative regulation of FasL biosynthetic process+++GO:0038113///interleukin-9-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0019221///cytokine-mediated signaling pathway","Janus kinase 3","[JAK3_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase JAK3; EC=2.7.10.2; AltName: Full=Janus kinase 3; Short=JAK-3; AltName: Full=Leukocyte janus kinase; Short=L-JAK;+++[A0A024R7M7_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|PIRNR:PIRNR000636, ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|PIRNR:PIRNR000636, ECO:0000256|RuleBase:RU362096};+++[A0A0S2Z485_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein kinase {ECO:0000256|RuleBase:RU362096}; EC=2.7.10.2 {ECO:0000256|RuleBase:RU362096}; Flags: Fragment;+++[A0A0S2Z4R7_HUMAN|Unreviewed]SubName: Full=Janus kinase 3 isoform 2 {ECO:0000313|EMBL:ALQ33612.1};"]
[374308,"'PTCHD3'",0,2,0,0.666666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005575///cellular_component+++GO:0097225///sperm midpiece+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0007286///spermatid development","patched domain containing 3","[PTHD3_HUMAN|Reviewed]RecName: Full=Patched domain-containing protein 3; AltName: Full=Patched-related protein;+++[A0A087WVH3_HUMAN|Unreviewed]SubName: Full=Patched domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000479436};+++[F6LPT1_HUMAN|Unreviewed]SubName: Full=PTCHD3 isoform 2 {ECO:0000313|EMBL:AEA72435.1};+++[I0CMK0_HUMAN|Unreviewed]SubName: Full=Patched domain-containing 3 {ECO:0000313|EMBL:AFH78581.1}; Flags: Fragment;"]
[374470,"'C12orf42'",0,2,0,0.666666666666667,{"$nulls":5},"GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","chromosome 12 open reading frame 42","[CL042_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C12orf42;+++[A0A024RBK7_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 42, isoform CRA_a {ECO:0000313|EMBL:EAW97705.1}; Flags: Fragment;+++[F8VV63_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf42 {ECO:0000313|Ensembl:ENSP00000449362};+++[F8VX61_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf42 {ECO:0000313|Ensembl:ENSP00000449447};+++[F8W1Y6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf42 {ECO:0000313|Ensembl:ENSP00000447795}; Flags: Fragment;"]
[374786,"'EFCAB5'",15,16,6,12.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0046872///metal ion binding+++GO:0005509///calcium ion binding",null,"EF-hand calcium binding domain 5","[EFCB5_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 5;+++[C9J1E6_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000400023}; Flags: Fragment;+++[H0Y4M1_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000392831};+++[H0Y843_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000417009}; Flags: Fragment;+++[K7EJC3_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000465109}; Flags: Fragment;"]
[374969,"'SVBP'",126,141,140,135.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0045177///apical part of cell","GO:0005515///protein binding","GO:0006508///proteolysis+++GO:0010596///negative regulation of endothelial cell migration+++GO:0031397///negative regulation of protein ubiquitination+++GO:0009306///protein secretion","small vasohibin binding protein","[SVBP_HUMAN|Reviewed]RecName: Full=Small vasohibin-binding protein {ECO:0000303|PubMed:20736312}; AltName: Full=Coiled coil domain-containing protein 23 {ECO:0000312|HGNC:HGNC:29204};"]
[375189,"'PFN4'",8,4,9,7,"05132///Salmonella infection+++04015///Rap1 signaling pathway+++04810///Regulation of actin cytoskeleton+++04013///MAPK signaling pathway - fly+++05131///Shigellosis","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005938///cell cortex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0003785///actin monomer binding+++GO:0008289///lipid binding","GO:0042989///sequestering of actin monomers","profilin family member 4","[PROF4_HUMAN|Reviewed]RecName: Full=Profilin-4; AltName: Full=Profilin IV;+++[A0A1D5RMN8_HUMAN|Unreviewed]SubName: Full=Profilin-4 {ECO:0000313|Ensembl:ENSP00000393504}; Flags: Fragment;"]
[375611,"'SLC26A5'",17.99,26.28,16.63,20.3,null,"H00605///Deafness, autosomal recessive",null,null,"GO:0005886///plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0015106///bicarbonate transmembrane transporter activity+++GO:0042803///protein homodimerization activity+++GO:0030507///spectrin binding+++GO:0015108///chloride transmembrane transporter activity+++GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0008134///transcription factor binding+++GO:0015301///anion:anion antiporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0019531///oxalate transmembrane transporter activity","GO:0034220///ion transmembrane transport+++GO:0015701///bicarbonate transport+++GO:1902358///sulfate transmembrane transport+++GO:1902074///response to salt+++GO:1902476///chloride transmembrane transport+++GO:0002931///response to ischemia+++GO:0055085///transmembrane transport+++GO:0015755///fructose transmembrane transport+++GO:0051262///protein tetramerization+++GO:0035864///response to potassium ion+++GO:0019532///oxalate transport+++GO:2000147///positive regulation of cell motility+++GO:0007605///sensory perception of sound+++GO:0097066///response to thyroid hormone+++GO:0090102///cochlea development+++GO:0098656///anion transmembrane transport+++GO:0008272///sulfate transport+++GO:0010996///response to auditory stimulus+++GO:0009751///response to salicylic acid+++GO:0042493///response to drug+++GO:0008360///regulation of cell shape+++GO:0034766///negative regulation of ion transmembrane transport+++GO:0045793///positive regulation of cell size+++GO:0042391///regulation of membrane potential","solute carrier family 26 member 5","[S26A5_HUMAN|Reviewed]RecName: Full=Prestin; AltName: Full=Solute carrier family 26 member 5;+++[E9PCM2_HUMAN|Unreviewed]RecName: Full=Prestin {ECO:0000256|RuleBase:RU362052}; AltName: Full=Solute carrier family 26 member 5 {ECO:0000256|RuleBase:RU362052};+++[F8WD50_HUMAN|Unreviewed]SubName: Full=Prestin {ECO:0000313|Ensembl:ENSP00000396833};+++[F8WDL4_HUMAN|Unreviewed]SubName: Full=Prestin {ECO:0000313|Ensembl:ENSP00000395568};+++[Q496J0_HUMAN|Unreviewed]SubName: Full=Prestin {ECO:0000313|Ensembl:ENSP00000416502}; SubName: Full=SLC26A5 protein {ECO:0000313|EMBL:AAI00836.1};+++[Q496J1_HUMAN|Unreviewed]SubName: Full=SLC26A5 protein {ECO:0000313|EMBL:AAI00835.1};+++[Q496J3_HUMAN|Unreviewed]SubName: Full=Prestin {ECO:0000313|Ensembl:ENSP00000389018}; SubName: Full=SLC26A5 protein {ECO:0000313|EMBL:AAI00833.1};+++[Q7Z7F4_HUMAN|Unreviewed]RecName: Full=Prestin {ECO:0000256|RuleBase:RU362052}; AltName: Full=Solute carrier family 26 member 5 {ECO:0000256|RuleBase:RU362052};"]
[3759,"'KCNJ2'",145,219,165,176.333333333333,"04924///Renin secretion+++04921///Oxytocin signaling pathway+++04725///Cholinergic synapse+++04971///Gastric acid secretion","H00720///Long QT syndrome+++H00215///Periodic paralysis+++H00731///Atrial fibrillation+++H00725///Short QT syndrome+++H00748///Andersen-Tawil syndrome (ATS)",null,null,"GO:0014704///intercalated disc+++GO:0043025///neuronal cell body+++GO:0016021///integral component of membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0005794///Golgi apparatus+++GO:0031224///intrinsic component of membrane+++GO:0043197///dendritic spine+++GO:0030425///dendrite+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005790///smooth endoplasmic reticulum+++GO:0005791///rough endoplasmic reticulum+++GO:0030315///T-tubule","GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0042802///identical protein binding+++GO:0015467///G-protein activated inward rectifier potassium channel activity+++GO:0086008///voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization+++GO:0005242///inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity","GO:0071260///cellular response to mechanical stimulus+++GO:0090076///relaxation of skeletal muscle+++GO:0015693///magnesium ion transport+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0030007///cellular potassium ion homeostasis+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0006811///ion transport+++GO:0060306///regulation of membrane repolarization+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086011///membrane repolarization during action potential+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:0055119///relaxation of cardiac muscle+++GO:0006813///potassium ion transport+++GO:0051289///protein homotetramerization+++GO:0034765///regulation of ion transmembrane transport+++GO:0086001///cardiac muscle cell action potential+++GO:0014861///regulation of skeletal muscle contraction via regulation of action potential+++GO:1990573///potassium ion import across plasma membrane+++GO:0086004///regulation of cardiac muscle cell contraction+++GO:0060075///regulation of resting membrane potential+++GO:0071805///potassium ion transmembrane transport","potassium voltage-gated channel subfamily J member 2","[KCNJ2_HUMAN|Reviewed]RecName: Full=Inward rectifier potassium channel 2; AltName: Full=Cardiac inward rectifier potassium channel; AltName: Full=Inward rectifier K(+) channel Kir2.1; Short=IRK-1; Short=hIRK1; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 2;"]
[3776,"'KCNK2'",9,18,21,16,"04934///Cushing's syndrome+++04927///Cortisol synthesis and secretion+++04971///Gastric acid secretion",{"$nulls":3},"GO:0097449///astrocyte projection+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0043005///neuron projection+++GO:0030424///axon+++GO:0005634///nucleus+++GO:0008076///voltage-gated potassium channel complex+++GO:0005886///plasma membrane+++GO:0044305///calyx of Held+++GO:0005887///integral component of plasma membrane+++GO:0043679///axon terminus+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane","GO:0005249///voltage-gated potassium channel activity+++GO:0019870///potassium channel inhibitor activity+++GO:0005267///potassium channel activity+++GO:0022841///potassium ion leak channel activity+++GO:0015271///outward rectifier potassium channel activity","GO:0010942///positive regulation of cell death+++GO:0042391///regulation of membrane potential+++GO:0090102///cochlea development+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:0048678///response to axon injury+++GO:0071805///potassium ion transmembrane transport+++GO:0007613///memory+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071456///cellular response to hypoxia+++GO:0006813///potassium ion transport+++GO:0003231///cardiac ventricle development+++GO:1900039///positive regulation of cellular response to hypoxia+++GO:0009612///response to mechanical stimulus+++GO:0006811///ion transport","potassium two pore domain channel subfamily K member 2","[KCNK2_HUMAN|Reviewed]RecName: Full=Potassium channel subfamily K member 2; AltName: Full=Outward rectifying potassium channel protein TREK-1; AltName: Full=TREK-1 K(+) channel subunit; AltName: Full=Two pore domain potassium channel TREK-1; AltName: Full=Two pore potassium channel TPKC1;+++[B4DGU6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58876, highly similar to Potassium channel subfamily K member 2 {ECO:0000313|EMBL:BAG57907.1};+++[C9JDK1_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 2 {ECO:0000313|Ensembl:ENSP00000420569}; Flags: Fragment;+++[C9JXY2_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 2 {ECO:0000313|Ensembl:ENSP00000413460}; Flags: Fragment;+++[F8WDE6_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 2 {ECO:0000313|Ensembl:ENSP00000420499};+++[Q6ZW95_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 2 {ECO:0000313|Ensembl:ENSP00000418706}; SubName: Full=cDNA FLJ41415 fis, clone BRHIP2001805, moderately similar to Homo sapiens TREK-1 potassium channel (KCNK2) mRNA {ECO:0000313|EMBL:BAC85609.1};+++[U3N6F0_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily k member 2 variant 2 {ECO:0000313|EMBL:AGW27106.1};+++[U3N834_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily k member 2 variant 1 {ECO:0000313|EMBL:AGW27105.1};"]
[3785,"'KCNQ2'",0,0,1,0.333333333333333,"04725///Cholinergic synapse","H00806///Benign familial neonatal and infantile epilepsies+++H00606///Early infantile epileptic encephalopathy",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0033268///node of Ranvier+++GO:0016021///integral component of membrane+++GO:0043194///axon initial segment+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex","GO:0005249///voltage-gated potassium channel activity+++GO:0005216///ion channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity+++GO:0030506///ankyrin binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005516///calmodulin binding+++GO:0005515///protein binding","GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport+++GO:0007399///nervous system development+++GO:0071805///potassium ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0006811///ion transport+++GO:0006813///potassium ion transport","potassium voltage-gated channel subfamily Q member 2","[KCNQ2_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000305}; AltName: Full=KQT-like 2; AltName: Full=Neuroblastoma-specific potassium channel subunit alpha KvLQT2; AltName: Full=Voltage-gated potassium channel subunit Kv7.2;+++[A0A0D9SEV1_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486040};+++[A0A0D9SF10_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486194};+++[A0A0D9SFE0_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486509}; Flags: Fragment;+++[A0A0D9SG49_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487142};+++[A0A0D9SGD4_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487384}; Flags: Fragment;+++[A0A0D9SGG3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487469}; Flags: Fragment;+++[A0A0D9SGJ7_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487563}; Flags: Fragment;+++[A0A0G2JH35_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000349789}; Flags: Fragment;+++[A0A0G2JQC9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000485756}; Flags: Fragment;+++[A0A0G2JQG6_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000485832}; Flags: Fragment;+++[A0A0G2JR54_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486451}; Flags: Fragment;+++[A0A0G2JR60_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486464}; Flags: Fragment;+++[A0A0G2JR98_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486557}; Flags: Fragment;+++[A0A0G2JRN9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000486949}; Flags: Fragment;+++[A0A0G2JRU6_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487078}; Flags: Fragment;+++[A0A0G2JS89_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487440}; Flags: Fragment;+++[A0A0G2JSD3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000487545}; Flags: Fragment;+++[A0A1B0GUK1_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000490142}; Flags: Fragment;+++[A0A1B0GW14_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000490734};+++[H0UI91_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2, isoform CRA_j {ECO:0000313|EMBL:EAW75281.1};+++[Q4VXP6_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily KQT member 2 {ECO:0000313|Ensembl:ENSP00000359244};+++[Q53Y30_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2 {ECO:0000313|EMBL:AAP35692.1}; SubName: Full=Potassium voltage-gated channel, KQT-like subfamily, member 2, isoform CRA_e {ECO:0000313|EMBL:EAW75275.1};"]
[3801,"'KIFC3'",343,468,436,415.666666666667,{"$nulls":4},"GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005856///cytoskeleton+++GO:0005871///kinesin complex+++GO:0005815///microtubule organizing center+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005915///zonula adherens+++GO:0030054///cell junction+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005912///adherens junction+++GO:0005813///centrosome+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0003774///motor activity+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0005524///ATP binding+++GO:0008569///ATP-dependent microtubule motor activity, minus-end-directed+++GO:0003777///microtubule motor activity","GO:0007601///visual perception+++GO:0007017///microtubule-based process+++GO:0090136///epithelial cell-cell adhesion+++GO:0045218///zonula adherens maintenance+++GO:0007018///microtubule-based movement+++GO:0007030///Golgi organization","kinesin family member C3","[KIFC3_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIFC3;+++[A0A0C4DGM9_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000458009};+++[B7Z5U4_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[B7Z808_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[B7Z896_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[F5H3M2_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[H3BMJ1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000454403}; Flags: Fragment;+++[H3BMQ3_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000454493}; Flags: Fragment;+++[H3BMR0_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000454501}; Flags: Fragment;+++[H3BMZ5_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000454615}; Flags: Fragment;+++[H3BNZ0_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000455067}; Flags: Fragment;+++[H3BPE2_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000455276}; Flags: Fragment;+++[H3BRQ1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000456354}; Flags: Fragment;+++[H3BSN2_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000456780}; Flags: Fragment;+++[H3BTE9_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000457144}; Flags: Fragment;+++[H3BTL6_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394}; Flags: Fragment;+++[H3BTN1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000457247}; Flags: Fragment;+++[H3BTU1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000457326}; Flags: Fragment;+++[H3BUC0_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000457568}; Flags: Fragment;+++[H3BV47_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIFC3 {ECO:0000313|Ensembl:ENSP00000457948}; Flags: Fragment;"]
[3839,"'KPNA3'",573,570,485,542.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0043657///host cell+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005829///cytosol","GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0008139///nuclear localization sequence binding+++GO:0008565///protein transporter activity","GO:0006607///NLS-bearing protein import into nucleus+++GO:0006606///protein import into nucleus+++GO:0016032///viral process+++GO:0015031///protein transport+++GO:0019054///modulation by virus of host process+++GO:0075732///viral penetration into host nucleus+++GO:0065003///protein-containing complex assembly+++GO:0046718///viral entry into host cell","karyopherin subunit alpha 3","[IMA4_HUMAN|Reviewed]RecName: Full=Importin subunit alpha-4; AltName: Full=Importin alpha Q2; Short=Qip2; AltName: Full=Karyopherin subunit alpha-3; AltName: Full=SRP1-gamma;+++[A0A024RDV7_HUMAN|Unreviewed]RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};+++[H0Y4S9_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-4 {ECO:0000313|Ensembl:ENSP00000393869}; Flags: Fragment;"]
[3860,"'KRT13'",10,1,8,6.33333333333333,"04915///Estrogen signaling pathway","H00684///Pachyonychia congenita+++H00723///Non-epidermolytic palmoplantar keratoderma (NEPPK)+++H00738///Ichthyosis with confetti+++H00708///Naegeli-Franceschetti-Jadassohn syndrome+++H01673///Palmoplantar keratoderma+++H00584///Epidermolysis bullosa simplex+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00796///Dermatopathia pigmentosa reticularis+++H00726///Meesmann corneal dystrophy+++H00724///White sponge nevus+++H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H00667///Woolly hair",null,null,"GO:0045095///keratin filament+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton+++GO:0005882///intermediate filament+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0005198///structural molecule activity","GO:0007010///cytoskeleton organization+++GO:0031424///keratinization+++GO:0070268///cornification","keratin 13","[K1C13_HUMAN|Reviewed]RecName: Full=Keratin, type I cytoskeletal 13; AltName: Full=Cytokeratin-13; Short=CK-13; AltName: Full=Keratin-13; Short=K13;+++[A1A4E9_HUMAN|Unreviewed]SubName: Full=Keratin 13 {ECO:0000313|EMBL:AAI26185.1}; SubName: Full=Keratin 13, isoform CRA_a {ECO:0000313|EMBL:EAW60740.1};+++[K7EMD9_HUMAN|Unreviewed]SubName: Full=Keratin, type I cytoskeletal 13 {ECO:0000313|Ensembl:ENSP00000466465}; Flags: Fragment;+++[K7EMJ2_HUMAN|Unreviewed]SubName: Full=Keratin, type I cytoskeletal 13 {ECO:0000313|Ensembl:ENSP00000466525};+++[K7EQH6_HUMAN|Unreviewed]SubName: Full=Keratin, type I cytoskeletal 13 {ECO:0000313|Ensembl:ENSP00000467833}; Flags: Fragment;+++[K7ERE3_HUMAN|Unreviewed]SubName: Full=Keratin, type I cytoskeletal 13 {ECO:0000313|Ensembl:ENSP00000468221};"]
[387357,"'THEMIS'",0,0,3,1,{"$nulls":4},"GO:0005911///cell-cell junction+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome","GO:0005515///protein binding","GO:0002250///adaptive immune response+++GO:0043383///negative T cell selection+++GO:0007275///multicellular organism development+++GO:0050852///T cell receptor signaling pathway+++GO:0043368///positive T cell selection+++GO:0002376///immune system process","thymocyte selection associated","[THMS1_HUMAN|Reviewed]RecName: Full=Protein THEMIS; AltName: Full=Thymocyte-expressed molecule involved in selection;+++[A0A0D9SFD2_HUMAN|Unreviewed]SubName: Full=Protein THEMIS {ECO:0000313|Ensembl:ENSP00000486494};+++[X1WI26_HUMAN|Unreviewed]SubName: Full=Protein THEMIS {ECO:0000313|Ensembl:ENSP00000387740}; Flags: Fragment;"]
[387763,"'C11orf96'",3,6,10,6.33333333333333,{"$nulls":7},"chromosome 11 open reading frame 96","[CK096_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf96; AltName: Full=Protein Ag2 homolog;+++[A0A087WW59_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf96 {ECO:0000313|Ensembl:ENSP00000479976};+++[E9PKL4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf96 {ECO:0000313|Ensembl:ENSP00000431597};"]
[388112,"'NANOGP8'",1.86,0.91,0,0.923333333333333,"04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer",{"$nulls":3},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003674///molecular_function+++GO:0043565///sequence-specific DNA binding","GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:0008284///positive regulation of cell proliferation+++GO:0006355///regulation of transcription, DNA-templated","Nanog homeobox retrogene P8","[NANP8_HUMAN|Reviewed]RecName: Full=Homeobox protein NANOGP8;+++[A0A0D9SG05_HUMAN|Unreviewed]SubName: Full=Homeobox protein NANOGP8 {ECO:0000313|Ensembl:ENSP00000487045};+++[J7H427_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90912.1}; Flags: Fragment;+++[J7H466_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90934.1}; Flags: Fragment;+++[J7H7A5_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90941.1}; Flags: Fragment;+++[J7H7C4_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90961.1}; Flags: Fragment;+++[J7H9Z3_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90938.1}; Flags: Fragment;+++[J7HA13_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90958.1}; Flags: Fragment;+++[J7HAY6_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90885.1}; Flags: Fragment;+++[J7HAZ5_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90900.1}; Flags: Fragment;+++[J7HB24_HUMAN|Unreviewed]SubName: Full=NANOGP8 {ECO:0000313|EMBL:AFP90940.1}; Flags: Fragment;"]
[3884,"'KRT33B'",16,14,14,14.6666666666667,"04915///Estrogen signaling pathway","H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H00723///Non-epidermolytic palmoplantar keratoderma (NEPPK)+++H00738///Ichthyosis with confetti+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00667///Woolly hair+++H01673///Palmoplantar keratoderma+++H00726///Meesmann corneal dystrophy+++H00708///Naegeli-Franceschetti-Jadassohn syndrome+++H00684///Pachyonychia congenita+++H00796///Dermatopathia pigmentosa reticularis+++H00584///Epidermolysis bullosa simplex+++H00724///White sponge nevus",null,null,"GO:0070062///extracellular exosome+++GO:0005882///intermediate filament+++GO:0005615///extracellular space+++GO:0005829///cytosol","GO:0005198///structural molecule activity+++GO:0005515///protein binding","GO:0031424///keratinization+++GO:0007568///aging+++GO:0070268///cornification+++GO:0042633///hair cycle","keratin 33B","[KT33B_HUMAN|Reviewed]RecName: Full=Keratin, type I cuticular Ha3-II; AltName: Full=Hair keratin, type I Ha3-II; AltName: Full=Keratin-33B; Short=K33B;"]
[388552,"'BLOC1S3'",196,154,197.99,182.663333333333,null,"H00166///Hermansky-Pudlak syndrome (HPS)",null,null,"GO:0005829///cytosol+++GO:0031083///BLOC-1 complex+++GO:1904115///axon cytoplasm+++GO:0030133///transport vesicle+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity+++GO:0003674///molecular_function","GO:0032816///positive regulation of natural killer cell activation+++GO:0043473///pigmentation+++GO:0048066///developmental pigmentation+++GO:0008089///anterograde axonal transport+++GO:0032438///melanosome organization+++GO:0071806///protein transmembrane transport+++GO:0007596///blood coagulation+++GO:0032402///melanosome transport+++GO:0001654///eye development+++GO:0030168///platelet activation+++GO:0048490///anterograde synaptic vesicle transport+++GO:0042493///response to drug+++GO:0035646///endosome to melanosome transport+++GO:0060155///platelet dense granule organization+++GO:0031175///neuron projection development+++GO:0033299///secretion of lysosomal enzymes","biogenesis of lysosomal organelles complex 1 subunit 3","[BL1S3_HUMAN|Reviewed]RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 3; Short=BLOC-1 subunit 3;+++[K7EN58_HUMAN|Unreviewed]SubName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 3 {ECO:0000313|Ensembl:ENSP00000466798}; Flags: Fragment;"]
[388677,"'NOTCH2NLA'",253.59,213.67,203.01,223.423333333333,"05224///Breast cancer+++04330///Notch signaling pathway+++04320///Dorso-ventral axis formation+++05200///Pathways in cancer+++05165///Human papillomavirus infection+++04919///Thyroid hormone signaling pathway+++04658///Th1 and Th2 cell differentiation+++01522///Endocrine resistance+++05206///MicroRNAs in cancer","H00551///Alagille syndrome+++H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0005112///Notch binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding","GO:0030154///cell differentiation+++GO:0021987///cerebral cortex development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway","notch 2 N-terminal like A","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NC_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[388849,"'CCDC188'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016409///palmitoyltransferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity","GO:0007626///locomotory behavior+++GO:0018345///protein palmitoylation+++GO:0034380///high-density lipoprotein particle assembly","coiled-coil domain containing 188","[CC188_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 188 {ECO:0000305};"]
[388939,"'PCARE'",140,54,30,74.6666666666667,{"$nulls":4},"GO:0042995///cell projection+++GO:0005929///cilium+++GO:0001750///photoreceptor outer segment+++GO:0001917///photoreceptor inner segment",null,"GO:0035845///photoreceptor cell outer segment organization+++GO:1903546///protein localization to photoreceptor outer segment+++GO:0007601///visual perception+++GO:0050896///response to stimulus","photoreceptor cilium actin regulator","[PCARE_HUMAN|Reviewed]RecName: Full=Photoreceptor cilium actin regulator {ECO:0000312|HGNC:HGNC:34383};"]
[389336,"'C5orf46'",392,454,562,469.333333333333,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0003674///molecular_function","GO:0008150///biological_process","chromosome 5 open reading frame 46","[CE046_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf46; Flags: Precursor;"]
[389421,"'LIN28B'",14,13,8,11.6666666666667,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0031047///gene silencing by RNA+++GO:0031123///RNA 3'-end processing+++GO:0031054///pre-miRNA processing+++GO:0010587///miRNA catabolic process+++GO:0006355///regulation of transcription, DNA-templated","lin-28 homolog B","[LN28B_HUMAN|Reviewed]RecName: Full=Protein lin-28 homolog B; Short=Lin-28B;+++[A0A1B0GTK2_HUMAN|Unreviewed]SubName: Full=Protein lin-28 homolog B {ECO:0000313|Ensembl:ENSP00000489735}; Flags: Fragment;+++[A0A1B0GVD3_HUMAN|Unreviewed]SubName: Full=Protein lin-28 homolog B {ECO:0000313|Ensembl:ENSP00000490468};+++[A7E2T3_HUMAN|Unreviewed]SubName: Full=LIN28B protein {ECO:0000313|EMBL:AAI50538.1}; Flags: Fragment;"]
[389895,"'LOC389895'",5,2,0,2.33333333333333,{"$nulls":7},"chromosome 16 open reading frame 72-like","[CP072_DANRE|diamond]RecName: Full=UPF0472 protein C16orf72 homolog;+++[CP072_HUMAN|diamond]RecName: Full=UPF0472 protein C16orf72;+++[CP072_MOUSE|diamond]RecName: Full=UPF0472 protein C16orf72 homolog;+++[CP072_XENLA|diamond]RecName: Full=UPF0472 protein C16orf72 homolog;+++[CP072_XENTR|diamond]RecName: Full=UPF0472 protein C16orf72 homolog;"]
[390077,"'OR52N2'",1,0,0,0.333333333333333,"04740///Olfactory transduction",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004984///olfactory receptor activity","GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","olfactory receptor family 52 subfamily N member 2","[O52N2_HUMAN|Reviewed]RecName: Full=Olfactory receptor 52N2; AltName: Full=Olfactory receptor OR11-57;+++[A0A126GWF5_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};"]
[391123,"'VSIG8'",0,1,1,0.666666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003723///RNA binding",null,"V-set and immunoglobulin domain containing 8","[VSIG8_HUMAN|Reviewed]RecName: Full=V-set and immunoglobulin domain-containing protein 8; Flags: Precursor;"]
[391712,"'TRIM61'",27,20.62,25,24.2066666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005622///intracellular+++GO:0016021///integral component of membrane+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","tripartite motif containing 61","[TRI61_HUMAN|Reviewed]RecName: Full=Putative tripartite motif-containing protein 61; AltName: Full=RING finger protein 35;"]
[392617,"'ELFN1'",1230,1136,1223,1196.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0060076///excitatory synapse+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0031012///extracellular matrix","GO:0004864///protein phosphatase inhibitor activity","GO:0010923///negative regulation of phosphatase activity+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0050808///synapse organization","extracellular leucine rich repeat and fibronectin type III domain containing 1","[ELFN1_HUMAN|Reviewed]RecName: Full=Protein ELFN1; AltName: Full=Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1; AltName: Full=Protein phosphatase 1 regulatory subunit 28; Flags: Precursor;"]
[3964,"'LGALS8'",774,782,800,785.333333333333,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005615///extracellular space+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0030246///carbohydrate binding+++GO:0005178///integrin binding+++GO:0005515///protein binding","GO:0098792///xenophagy+++GO:0098586///cellular response to virus+++GO:0006914///autophagy+++GO:1904977///lymphatic endothelial cell migration","galectin 8","[LEG8_HUMAN|Reviewed]RecName: Full=Galectin-8 {ECO:0000303|Ref.2}; Short=Gal-8; AltName: Full=Po66 carbohydrate-binding protein; Short=Po66-CBP; AltName: Full=Prostate carcinoma tumor antigen 1 {ECO:0000303|PubMed:8692978}; Short=PCTA-1 {ECO:0000303|PubMed:8692978};+++[A0A024R3S4_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};+++[A0A024R3X1_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};+++[B1ANM0_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[B3F166_HUMAN|Unreviewed]SubName: Full=Galectin-8g {ECO:0000313|EMBL:ABQ63077.1}; Flags: Fragment;+++[E9PJ77_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[E9PN19_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};+++[E9PNC2_HUMAN|Unreviewed]SubName: Full=Galectin-8 {ECO:0000313|Ensembl:ENSP00000413278};+++[E9PPL1_HUMAN|Unreviewed]SubName: Full=Galectin-8 {ECO:0000313|Ensembl:ENSP00000437007}; Flags: Fragment;+++[E9PPM4_HUMAN|Unreviewed]SubName: Full=Galectin-8 {ECO:0000313|Ensembl:ENSP00000407428};+++[E9PRN3_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[F6V2D4_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};+++[H7BXD8_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[L8E9E9_HUMAN|Unreviewed]SubName: Full=Alternative protein LGALS8 {ECO:0000313|EMBL:CCQ43361.1};+++[Q5T3P9_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[Q96QS7_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};"]
[398,"'ARHGDIG'",234,318,386,312.666666666667,"04722///Neurotrophin signaling pathway+++04962///Vasopressin-regulated water reabsorption","H01657///Nephrotic syndrome",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005096///GTPase activator activity+++GO:0030695///GTPase regulator activity+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0048365///Rac GTPase binding+++GO:0005515///protein binding+++GO:0005094///Rho GDP-dissociation inhibitor activity","GO:0050790///regulation of catalytic activity+++GO:0007162///negative regulation of cell adhesion+++GO:0001835///blastocyst hatching+++GO:0032880///regulation of protein localization+++GO:0007266///Rho protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GDP dissociation inhibitor gamma","[GDIR3_HUMAN|Reviewed]RecName: Full=Rho GDP-dissociation inhibitor 3; Short=Rho GDI 3; AltName: Full=Rho-GDI gamma;+++[A2ID99_HUMAN|Unreviewed]SubName: Full=Rho GDP dissociation inhibitor (GDI) gamma {ECO:0000313|EMBL:CAM26353.1}; SubName: Full=Rho GDP-dissociation inhibitor 3 {ECO:0000313|Ensembl:ENSP00000404435}; Flags: Fragment;+++[A2IDA0_HUMAN|Unreviewed]SubName: Full=Rho GDP dissociation inhibitor (GDI) gamma {ECO:0000313|EMBL:CAM26354.1}; Flags: Fragment;+++[A2IDA1_HUMAN|Unreviewed]SubName: Full=Rho GDP dissociation inhibitor (GDI) gamma {ECO:0000313|EMBL:CAM26355.1}; Flags: Fragment;+++[C9J3B5_HUMAN|Unreviewed]SubName: Full=Rho GDP-dissociation inhibitor 3 {ECO:0000313|Ensembl:ENSP00000410541}; Flags: Fragment;+++[C9J9L9_HUMAN|Unreviewed]SubName: Full=Rho GDP-dissociation inhibitor 3 {ECO:0000313|Ensembl:ENSP00000397395}; Flags: Fragment;+++[C9JR26_HUMAN|Unreviewed]SubName: Full=Rho GDP-dissociation inhibitor 3 {ECO:0000313|Ensembl:ENSP00000408037}; Flags: Fragment;+++[F1T0H7_HUMAN|Unreviewed]SubName: Full=HCG1985507, isoform CRA_a {ECO:0000313|EMBL:EAW85837.1}; SubName: Full=Rho GDP-dissociation inhibitor 3 {ECO:0000313|EMBL:BAJ84051.1};+++[Q4TT68_HUMAN|Unreviewed]SubName: Full=Rho GDP dissociation inhibitor (GDI) gamma {ECO:0000313|EMBL:CAI95585.1}; Flags: Fragment;"]
[399726,"'CASC10'",27,26,28,27,{"$nulls":7},"cancer susceptibility 10","[CSC10_HUMAN|Reviewed]RecName: Full=Protein CASC10; AltName: Full=Cancer susceptibility candidate gene 10 protein;"]
[400258,"'C14orf180'",177,85,140,134,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane",null,null,"chromosome 14 open reading frame 180","[NRAC_HUMAN|Reviewed]RecName: Full=Nutritionally-regulated adipose and cardiac enriched protein homolog;+++[A0A024R6Q4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW81865.1};+++[B4DN93_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53067 {ECO:0000313|EMBL:BAG60155.1};+++[J3KNP8_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 180 {ECO:0000313|Ensembl:ENSP00000333041};"]
[400506,"'KNOP1'",276,291,280,282.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003723///RNA binding","GO:0032465///regulation of cytokinesis+++GO:0016579///protein deubiquitination+++GO:0006893///Golgi to plasma membrane transport+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0051298///centrosome duplication+++GO:0015031///protein transport+++GO:0032053///ciliary basal body organization+++GO:0007099///centriole replication+++GO:0043312///neutrophil degranulation+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:1902018///negative regulation of cilium assembly+++GO:0045724///positive regulation of cilium assembly","lysine rich nucleolar protein 1","[KNOP1_HUMAN|Reviewed]RecName: Full=Lysine-rich nucleolar protein 1; AltName: Full=Protein FAM191A; AltName: Full=Testis-specific gene 118 protein;+++[H3BMC9_HUMAN|Unreviewed]SubName: Full=Lysine-rich nucleolar protein 1 {ECO:0000313|Ensembl:ENSP00000454329}; Flags: Fragment;+++[H3BNU8_HUMAN|Unreviewed]SubName: Full=Lysine-rich nucleolar protein 1 {ECO:0000313|Ensembl:ENSP00000455015};+++[H3BPL4_HUMAN|Unreviewed]SubName: Full=Lysine-rich nucleolar protein 1 {ECO:0000313|Ensembl:ENSP00000455369}; Flags: Fragment;"]
[400986,"'ANKRD36C'",52.39,22.25,14.04,29.56,{"$nulls":5},"GO:0008200///ion channel inhibitor activity",null,"ankyrin repeat domain 36C","[AN36C_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 36C; AltName: Full=Protein immuno-reactive with anti-PTH polyclonal antibodies;+++[A0A087WYV7_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36C {ECO:0000313|Ensembl:ENSP00000482131};+++[A0A0C4DH05_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36C {ECO:0000313|Ensembl:ENSP00000485004};+++[E9PJI0_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36C {ECO:0000313|Ensembl:ENSP00000431824};+++[H0YDI7_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36C {ECO:0000313|Ensembl:ENSP00000433685}; Flags: Fragment;+++[I1Z9D4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 36C {ECO:0000313|EMBL:AFJ19145.1}; Flags: Fragment;"]
[401097,"'C3orf80'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"chromosome 3 open reading frame 80","[CC080_HUMAN|Reviewed]RecName: Full=Uncharacterized membrane protein C3orf80; Flags: Precursor;+++[A0A1W2PNY3_HUMAN|Unreviewed]SubName: Full=Uncharacterized membrane protein C3orf80 {ECO:0000313|Ensembl:ENSP00000491138}; Flags: Fragment;"]
[401258,"'RAB44'",1,3,2,2,{"$nulls":4},"GO:0035579///specific granule membrane+++GO:0005886///plasma membrane+++GO:0035577///azurophil granule membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding","GO:0006886///intracellular protein transport+++GO:0043312///neutrophil degranulation+++GO:0032482///Rab protein signal transduction","RAB44, member RAS oncogene family","[RAB44_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-44;"]
[401562,"'LCNL1'",361,181,207,249.666666666667,{"$nulls":5},"GO:0036094///small molecule binding",null,"lipocalin like 1","[LCNL1_HUMAN|Reviewed]RecName: Full=Lipocalin-like 1 protein;+++[B9EHA8_HUMAN|Unreviewed]SubName: Full=Lipocalin-like 1 {ECO:0000313|EMBL:AAI37560.1};"]
[402055,"'SRRD'",380,417,404,400.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0042803///protein homodimerization activity+++GO:0003676///nucleic acid binding+++GO:0008476///protein-tyrosine sulfotransferase activity","GO:0007017///microtubule-based process+++GO:0048511///rhythmic process+++GO:0007623///circadian rhythm","SRR1 domain containing","[SRR1L_HUMAN|Reviewed]RecName: Full=SRR1-like protein; AltName: Full=SRR1 domain-containing protein;"]
[4034,"'LRCH4'",971,1066.16,1150,1062.38666666667,"04064///NF-kappa B signaling pathway+++04210///Apoptosis+++04115///p53 signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0016605///PML body+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome","GO:0005515///protein binding","GO:0007399///nervous system development+++GO:0008542///visual learning+++GO:0007616///long-term memory+++GO:0051965///positive regulation of synapse assembly","leucine rich repeats and calponin homology domain containing 4","[LRCH4_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat and calponin homology domain-containing protein 4; AltName: Full=Leucine-rich repeat neuronal protein 4; Short=Leucine-rich neuronal protein;+++[A0A087X197_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and calponin homology domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000483999};+++[C9JYK0_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and calponin homology domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000419870};+++[H7C5D9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and calponin homology domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000419674}; Flags: Fragment;"]
[404636,"'FAM45A'",839,834,744,805.666666666667,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005769///early endosome+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0043209///myelin sheath","GO:0042802///identical protein binding+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0008379///thioredoxin peroxidase activity+++GO:0008785///alkyl hydroperoxide reductase activity+++GO:0019900///kinase binding","GO:0034614///cellular response to reactive oxygen species+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0018171///peptidyl-cysteine oxidation+++GO:0001893///maternal placenta development+++GO:0008284///positive regulation of cell proliferation+++GO:0034599///cellular response to oxidative stress+++GO:0030099///myeloid cell differentiation+++GO:0033673///negative regulation of kinase activity+++GO:0045454///cell redox homeostasis+++GO:0007005///mitochondrion organization+++GO:0043066///negative regulation of apoptotic process+++GO:0006979///response to oxidative stress+++GO:0042744///hydrogen peroxide catabolic process+++GO:0042542///response to hydrogen peroxide+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0032496///response to lipopolysaccharide","family with sequence similarity 45 member A","[FA45A_HUMAN|Reviewed]RecName: Full=Protein FAM45A;+++[B4DMU4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59935, highly similar to Protein FAM45A {ECO:0000313|EMBL:BAG60006.1};+++[B4DNL9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55853, highly similar to Protein FAM45A {ECO:0000313|EMBL:BAG60281.1};"]
[406,"'ARNTL'",433,606.99,489,509.663333333333,"04710///Circadian rhythm+++04728///Dopaminergic synapse+++05168///Herpes simplex infection+++04711///Circadian rhythm - fly",{"$nulls":3},"GO:0033391///chromatoid body+++GO:0016605///PML body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005667///transcription factor complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016604///nuclear body","GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0051879///Hsp90 protein binding+++GO:0070888///E-box binding+++GO:0046983///protein dimerization activity+++GO:0043425///bHLH transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0070491///repressing transcription factor binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048511///rhythmic process+++GO:0007623///circadian rhythm+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:2001016///positive regulation of skeletal muscle cell differentiation+++GO:0007283///spermatogenesis+++GO:2000074///regulation of type B pancreatic cell development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000060///protein import into nucleus, translocation+++GO:0060137///maternal process involved in parturition+++GO:0050796///regulation of insulin secretion+++GO:2000772///regulation of cellular senescence+++GO:0042176///regulation of protein catabolic process+++GO:1901985///positive regulation of protein acetylation+++GO:0090403///oxidative stress-induced premature senescence+++GO:0032922///circadian regulation of gene expression+++GO:0051775///response to redox state+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045599///negative regulation of fat cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042753///positive regulation of circadian rhythm+++GO:0050767///regulation of neurogenesis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000323///negative regulation of glucocorticoid receptor signaling pathway+++GO:0042634///regulation of hair cycle+++GO:0032007///negative regulation of TOR signaling+++GO:0051726///regulation of cell cycle","aryl hydrocarbon receptor nuclear translocator like","[BMAL1_HUMAN|Reviewed]RecName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1; AltName: Full=Basic-helix-loop-helix-PAS protein MOP3; AltName: Full=Brain and muscle ARNT-like 1; AltName: Full=Class E basic helix-loop-helix protein 5; Short=bHLHe5; AltName: Full=Member of PAS protein 3; AltName: Full=PAS domain-containing protein 3; AltName: Full=bHLH-PAS protein JAP3;+++[A0A140VKD3_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 50e {ECO:0000313|EMBL:AEE61270.1};+++[B2RCL8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ96151, highly similar to Homo sapiens aryl hydrocarbon receptor nuclear translocator-like(ARNTL), mRNA {ECO:0000313|EMBL:BAG37615.1};+++[E9PI92_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000436721}; Flags: Fragment;+++[E9PKF0_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000433571}; Flags: Fragment;+++[E9PKG7_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000433540}; Flags: Fragment;+++[E9PKN1_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000431566}; Flags: Fragment;+++[E9PL54_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000431488}; Flags: Fragment;+++[E9PNI4_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000434781}; Flags: Fragment;+++[E9PPV4_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000436313}; Flags: Fragment;+++[E9PRB1_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000434263}; Flags: Fragment;+++[E9PSD2_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000434044}; Flags: Fragment;+++[H0YER9_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000313|Ensembl:ENSP00000436442}; Flags: Fragment;"]
[408,"'ARRB1'",323,258,263,281.333333333333,"04010///MAPK signaling pathway+++04062///Chemokine signaling pathway+++04740///Olfactory transduction+++04144///Endocytosis+++05032///Morphine addiction+++04340///Hedgehog signaling pathway+++04926///Relaxin signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0030659///cytoplasmic vesicle membrane+++GO:0005654///nucleoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0016604///nuclear body+++GO:0005905///clathrin-coated pit+++GO:0005765///lysosomal membrane+++GO:0031143///pseudopodium+++GO:0045211///postsynaptic membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane+++GO:0014069///postsynaptic density+++GO:0005768///endosome+++GO:0000785///chromatin+++GO:0005829///cytosol+++GO:0043197///dendritic spine+++GO:0000139///Golgi membrane","GO:0031691///alpha-1A adrenergic receptor binding+++GO:0035615///clathrin adaptor activity+++GO:0031762///follicle-stimulating hormone receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0031701///angiotensin receptor binding+++GO:0005096///GTPase activator activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0044325///ion channel binding+++GO:0004857///enzyme inhibitor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0031692///alpha-1B adrenergic receptor binding+++GO:1990763///arrestin family protein binding+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0030331///estrogen receptor binding+++GO:0051219///phosphoprotein binding+++GO:0019899///enzyme binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0045309///protein phosphorylated amino acid binding+++GO:0030276///clathrin binding+++GO:0043027///cysteine-type endopeptidase inhibitor activity involved in apoptotic process+++GO:0005102///signaling receptor binding+++GO:0004402///histone acetyltransferase activity+++GO:0031896///V2 vasopressin receptor binding+++GO:0005159///insulin-like growth factor receptor binding","GO:0042981///regulation of apoptotic process+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0032092///positive regulation of protein binding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0009968///negative regulation of signal transduction+++GO:0032715///negative regulation of interleukin-6 production+++GO:0042699///follicle-stimulating hormone signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0035066///positive regulation of histone acetylation+++GO:0000187///activation of MAPK activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0006897///endocytosis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0034260///negative regulation of GTPase activity+++GO:0090240///positive regulation of histone H4 acetylation+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0042493///response to drug+++GO:0032717///negative regulation of interleukin-8 production+++GO:0031397///negative regulation of protein ubiquitination+++GO:0015031///protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043149///stress fiber assembly+++GO:0016573///histone acetylation+++GO:0007602///phototransduction+++GO:0043547///positive regulation of GTPase activity+++GO:0006366///transcription by RNA polymerase II+++GO:0001933///negative regulation of protein phosphorylation+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0006915///apoptotic process+++GO:0061024///membrane organization+++GO:0001934///positive regulation of protein phosphorylation+++GO:0030168///platelet activation+++GO:0002031///G protein-coupled receptor internalization+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0002092///positive regulation of receptor internalization+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process","arrestin beta 1","[ARRB1_HUMAN|Reviewed]RecName: Full=Beta-arrestin-1; AltName: Full=Arrestin beta-1; AltName: Full=Non-visual arrestin-2 {ECO:0000303|PubMed:23886940};+++[B7Z1Q3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53544 {ECO:0000313|EMBL:BAH11589.1};+++[E9PM35_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-1 {ECO:0000313|Ensembl:ENSP00000433171}; Flags: Fragment;+++[H0YD81_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-1 {ECO:0000313|Ensembl:ENSP00000433137}; Flags: Fragment;+++[H0YDS1_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-1 {ECO:0000313|Ensembl:ENSP00000434196}; Flags: Fragment;+++[H0YEQ2_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-1 {ECO:0000313|Ensembl:ENSP00000436352}; Flags: Fragment;+++[H0YET9_HUMAN|Unreviewed]SubName: Full=Beta-arrestin-1 {ECO:0000313|Ensembl:ENSP00000436530}; Flags: Fragment;"]
[4097,"'MAFG'",595,767,534,632,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding","GO:0030641///regulation of cellular pH+++GO:0045604///regulation of epidermal cell differentiation+++GO:0007596///blood coagulation+++GO:0042127///regulation of cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030534///adult behavior+++GO:0010628///positive regulation of gene expression+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development","MAF bZIP transcription factor G","[MAFG_HUMAN|Reviewed]RecName: Full=Transcription factor MafG; AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog G; AltName: Full=hMAF;+++[A0A024R8X1_HUMAN|Unreviewed]SubName: Full=HCG1991559, isoform CRA_f {ECO:0000313|EMBL:EAW89715.1};+++[I3L2F8_HUMAN|Unreviewed]SubName: Full=Transcription factor MafG {ECO:0000313|Ensembl:ENSP00000459634}; Flags: Fragment;"]
[4129,"'MAOB'",363,265,270,299.333333333333,"05031///Amphetamine addiction+++00330///Arginine and proline metabolism+++00950///Isoquinoline alkaloid biosynthesis+++01100///Metabolic pathways+++00260///Glycine, serine and threonine metabolism+++04728///Dopaminergic synapse+++05034///Alcoholism+++00360///Phenylalanine metabolism+++00350///Tyrosine metabolism+++01110///Biosynthesis of secondary metabolites+++05030///Cocaine addiction+++04726///Serotonergic synapse+++00340///Histidine metabolism+++00380///Tryptophan metabolism+++00982///Drug metabolism - cytochrome P450","H00548///Brunner syndrome+++H01450///Obsessive-compulsive disorder (OCD)","M00135///GABA biosynthesis, eukaryotes, putrescine => GABA","R02529///aminoacetone:oxygen oxidoreductase(deaminating)   Aminoacetone + H2O + Oxygen <=> Methylglyoxal + Ammonia + Hydrogen peroxide+++R04300///4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)   Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R02532///4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)   L-Noradrenaline + H2O + Oxygen <=> 3,4-Dihydroxymandelaldehyde + Ammonia + Hydrogen peroxide+++R08348///didemethylcitalopram:oxygen oxidoreductase(deaminating)(flavin-containing)   Didemethylcitalopram + H2O + Oxygen <=> Citalopram aldehyde + Ammonia + Hydrogen peroxide+++R04893///L-Normetanephrine:oxygen oxidoreductase (deaminating) (copper-containing)   L-Normetanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Ammonia + Hydrogen peroxide+++R02382///Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing)   Tyramine + H2O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R02613///Phenethylamine:oxygen oxidoreductase (deaminating)   Phenethylamine + Oxygen + H2O <=> Phenylacetaldehyde + Ammonia + Hydrogen peroxide+++R02173///Tryptamine:oxygen oxidoreductase(deaminating)   Tryptamine + H2O + Oxygen <=> Indole-3-acetaldehyde + Ammonia + Hydrogen peroxide+++R04890///3-Methoxytyramine:oxygen oxidoreductase (deaminating) (copper-containing)   3-Methoxytyramine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylacetaldehyde + Hydrogen peroxide + Ammonia+++R04908///5-Hydroxykynurenamine:oxygen oxidoreductase(deaminating)(flavin-containing)   5-Hydroxykynurenamine + H2O + Oxygen <=> 4,6-Dihydroxyquinoline + Ammonia + Hydrogen peroxide + H2O+++R11354///RCH2NHR':oxygen oxidoreductase (deaminating)   RCH2NHR' + H2O + Oxygen <=> Aldehyde + R'NH2 + Hydrogen peroxide+++R02908///5-Hydroxytryptamine:oxygen oxidoreductase(deaminating)(flavin-containing)   Serotonin + H2O + Oxygen <=> 5-Hydroxyindoleacetaldehyde + Ammonia + Hydrogen peroxide+++R08346///Citalopram:oxygen oxidoreductase(deaminating)(flavin-containing)   Citalopram + Oxygen + H2O <=> Citalopram aldehyde + Dimethylamine + Hydrogen peroxide+++R08347///Demethylcitalopram:oxygen oxidoreductase(deaminating)(flavin-containing)   Demethylcitalopram + Oxygen + H2O <=> Citalopram aldehyde + Methylamine + Hydrogen peroxide+++R04025///N-Acetylputrescine:oxygen oxidoreductase(deaminating)(flavin-containing)   N-Acetylputrescine + H2O + Oxygen <=> N4-Acetylaminobutanal + Ammonia + Hydrogen peroxide+++R04907///3-Hydroxykynurenamine:oxygen oxidoreductase(deaminating)(flavin-containing)   3-Hydroxykynurenamine + Oxygen <=> 4,8-Dihydroxyquinoline + Ammonia + Hydrogen peroxide+++R02919///4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)   L-Adrenaline + H2O + Oxygen <=> 3,4-Dihydroxymandelaldehyde + Methylamine + Hydrogen peroxide+++R04894///L-Metanephrine:oxygen oxidoreductase (deaminating) (flavin-containing)   L-Metanephrine + H2O + Oxygen <=> 3-Methoxy-4-hydroxyphenylglycolaldehyde + Hydrogen peroxide + Methylamine+++R04674///N-methylhistamine:oxygen oxidoreductase (deaminating)   N-Methylhistamine + H2O + Oxygen <=> Methylimidazole acetaldehyde + Ammonia + Hydrogen peroxide","GO:0016020///membrane+++GO:0005740///mitochondrial envelope+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0050660///flavin adenine dinucleotide binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0008131///primary amine oxidase activity+++GO:0042803///protein homodimerization activity","GO:0042420///dopamine catabolic process+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0045471///response to ethanol+++GO:0009636///response to toxic substance+++GO:0021762///substantia nigra development+++GO:0010269///response to selenium ion+++GO:0022900///electron transport chain+++GO:0010044///response to aluminum ion+++GO:0042493///response to drug+++GO:0042135///neurotransmitter catabolic process+++GO:0014063///negative regulation of serotonin secretion+++GO:0032496///response to lipopolysaccharide+++GO:0048545///response to steroid hormone+++GO:0051412///response to corticosterone+++GO:0045964///positive regulation of dopamine metabolic process+++GO:0055114///oxidation-reduction process","monoamine oxidase B","[AOFB_HUMAN|Reviewed]RecName: Full=Amine oxidase [flavin-containing] B; EC=1.4.3.4; AltName: Full=Monoamine oxidase type B; Short=MAO-B;+++[B7Z242_HUMAN|Unreviewed]RecName: Full=Amine oxidase {ECO:0000256|RuleBase:RU362067}; EC=1.4.3.- {ECO:0000256|RuleBase:RU362067};+++[Q8TBI1_HUMAN|Unreviewed]RecName: Full=Amine oxidase {ECO:0000256|RuleBase:RU362067}; EC=1.4.3.- {ECO:0000256|RuleBase:RU362067};"]
[414189,"'AGAP6'",253.49,265.57,204.05,241.036666666667,"04212///Longevity regulating pathway - worm",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity","ArfGAP with GTPase domain, ankyrin repeat and PH domain 6","[AGAP6_HUMAN|Reviewed]RecName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6; Short=AGAP-6; AltName: Full=Centaurin-gamma-like family member 3;+++[A0A087X0I8_HUMAN|Unreviewed]SubName: Full=Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000483426};"]
[4154,"'MBNL1'",1049,955,664,889.333333333333,{"$nulls":4},"GO:0010494///cytoplasmic stress granule+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003725///double-stranded RNA binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0001069///regulatory region RNA binding","GO:0030326///embryonic limb morphogenesis+++GO:0008380///RNA splicing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0043484///regulation of RNA splicing+++GO:0045445///myoblast differentiation+++GO:0007399///nervous system development+++GO:0006397///mRNA processing+++GO:0001701///in utero embryonic development","muscleblind like splicing regulator 1","[MBNL1_HUMAN|Reviewed]RecName: Full=Muscleblind-like protein 1; AltName: Full=Triplet-expansion RNA-binding protein;+++[A0A0A0MQX8_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000282488};+++[C9J4T8_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000417169}; Flags: Fragment;+++[C9J7P7_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000417741}; Flags: Fragment;+++[C9JCX1_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000420680}; Flags: Fragment;+++[C9JP00_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000420327};+++[H7C4T5_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000418109}; Flags: Fragment;+++[H7C4Y1_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000418508}; Flags: Fragment;+++[Q86VM6_HUMAN|Unreviewed]SubName: Full=MBNL1 protein {ECO:0000313|EMBL:AAH50535.1}; SubName: Full=Muscleblind-like (Drosophila), isoform CRA_f {ECO:0000313|EMBL:EAW78780.1}; SubName: Full=Muscleblind-like protein 1 {ECO:0000313|Ensembl:ENSP00000419347};"]
[4173,"'MCM4'",431,406,405,414,"04113///Meiosis - yeast+++04111///Cell cycle - yeast+++04110///Cell cycle+++03030///DNA replication",null,"M00285///MCM complex",null,"GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0042555///MCM complex","GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0017111///nucleoside-triphosphatase activity+++GO:0003697///single-stranded DNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003678///DNA helicase activity+++GO:0005515///protein binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0004386///helicase activity","GO:0032508///DNA duplex unwinding+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006270///DNA replication initiation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle","minichromosome maintenance complex component 4","[MCM4_HUMAN|Reviewed]RecName: Full=DNA replication licensing factor MCM4; EC=3.6.4.12; AltName: Full=CDC21 homolog; AltName: Full=P1-CDC21;+++[A0A024R7U6_HUMAN|Unreviewed]RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00536514}; EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00536514};+++[A4FS09_HUMAN|Unreviewed]SubName: Full=Minichromosome maintenance protein 4 {ECO:0000313|EMBL:CAM35476.1}; EC=3.6.1.15 {ECO:0000313|EMBL:CAM35476.1}; Flags: Fragment;+++[B3KMX0_HUMAN|Unreviewed]RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00536514}; EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00536514};+++[B4DLA6_HUMAN|Unreviewed]RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00536514}; EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00536514};+++[E5RFJ8_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000428833}; Flags: Fragment;+++[E5RFR3_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000430329}; Flags: Fragment;+++[E5RG31_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000427875}; Flags: Fragment;+++[E5RG53_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000427829};+++[E5RHP5_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000430864}; Flags: Fragment;"]
[4205,"'MEF2A'",1596.01,1396,1149,1380.33666666667,"05418///Fluid shear stress and atherosclerosis+++04371///Apelin signaling pathway+++04013///MAPK signaling pathway - fly+++04928///Parathyroid hormone synthesis, secretion and action+++04022///cGMP-PKG signaling pathway","H01742///Coronary artery disease",null,null,"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin","GO:0019901///protein kinase binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0046332///SMAD binding+++GO:0003713///transcription coactivator activity+++GO:0046982///protein heterodimerization activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0035035///histone acetyltransferase binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0043565///sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0042826///histone deacetylase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0033613///activating transcription factor binding","GO:0007399///nervous system development+++GO:0061337///cardiac conduction+++GO:0000002///mitochondrial genome maintenance+++GO:0007507///heart development+++GO:0055005///ventricular cardiac myofibril assembly+++GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0071277///cellular response to calcium ion+++GO:0070375///ERK5 cascade+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0000165///MAPK cascade+++GO:0046326///positive regulation of glucose import+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0007517///muscle organ development+++GO:0048813///dendrite morphogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048311///mitochondrion distribution+++GO:0007275///multicellular organism development+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0030154///cell differentiation","myocyte enhancer factor 2A","[MEF2A_HUMAN|Reviewed]RecName: Full=Myocyte-specific enhancer factor 2A; AltName: Full=Serum response factor-like protein 1;+++[A0A0S2Z417_HUMAN|Unreviewed]SubName: Full=Myocyte enhancer factor 2A isoform 4 {ECO:0000313|EMBL:ALQ33642.1}; Flags: Fragment;+++[A0A0S2Z453_HUMAN|Unreviewed]SubName: Full=MADS box transcription enhancer factor 2, polypeptide A (Myocyte enhancer factor 2A), isoform CRA_a {ECO:0000313|EMBL:EAX02249.1}; SubName: Full=Myocyte enhancer factor 2A isoform 2 {ECO:0000313|EMBL:ALQ33640.1}; Flags: Fragment;+++[A0A0S2Z454_HUMAN|Unreviewed]SubName: Full=MADS box transcription enhancer factor 2, polypeptide A (Myocyte enhancer factor 2A), isoform CRA_b {ECO:0000313|EMBL:EAX02250.1}; SubName: Full=Myocyte enhancer factor 2A isoform 1 {ECO:0000313|EMBL:ALQ33639.1}; Flags: Fragment;+++[A0A0S2Z4C8_HUMAN|Unreviewed]SubName: Full=Myocyte enhancer factor 2A isoform 5 {ECO:0000313|EMBL:ALQ33643.1}; Flags: Fragment;+++[A0A0S2Z4N0_HUMAN|Unreviewed]SubName: Full=MADS box transcription enhancer factor 2, polypeptide A (Myocyte enhancer factor 2A), isoform CRA_d {ECO:0000313|EMBL:EAX02252.1}; SubName: Full=Myocyte enhancer factor 2A isoform 3 {ECO:0000313|EMBL:ALQ33641.1}; Flags: Fragment;+++[A8K720_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75040, highly similar to Homo sapiens serum response factor-related protein, RSRFC9 {ECO:0000313|EMBL:BAF84524.1};+++[H0YKY6_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2A {ECO:0000313|Ensembl:ENSP00000452989}; Flags: Fragment;+++[H0YM62_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2A {ECO:0000313|Ensembl:ENSP00000453478}; Flags: Fragment;+++[H0YNI2_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2A {ECO:0000313|Ensembl:ENSP00000454023}; Flags: Fragment;+++[L0R504_HUMAN|Unreviewed]SubName: Full=Alternative protein MEF2A {ECO:0000313|EMBL:CCO13768.1};"]
[4218,"'RAB8A'",1150,1102,1306,1186,"04144///Endocytosis+++04530///Tight junction+++04972///Pancreatic secretion+++04152///AMPK signaling pathway",{"$nulls":3},"GO:0032588///trans-Golgi network membrane+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0043025///neuronal cell body+++GO:0055037///recycling endosome+++GO:0030140///trans-Golgi network transport vesicle+++GO:0005814///centriole+++GO:0031410///cytoplasmic vesicle+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0036064///ciliary basal body+++GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0008021///synaptic vesicle+++GO:0043197///dendritic spine+++GO:0005794///Golgi apparatus+++GO:0055038///recycling endosome membrane+++GO:0030496///midbody+++GO:0098978///glutamatergic synapse+++GO:0097730///non-motile cilium+++GO:0045202///synapse+++GO:0005929///cilium+++GO:0014069///postsynaptic density+++GO:0000139///Golgi membrane+++GO:0045335///phagocytic vesicle+++GO:0097546///ciliary base+++GO:0030425///dendrite","GO:0005525///GTP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0031489///myosin V binding+++GO:0019003///GDP binding+++GO:0003924///GTPase activity+++GO:0019901///protein kinase binding+++GO:0017137///Rab GTPase binding","GO:0072659///protein localization to plasma membrane+++GO:0032869///cellular response to insulin stimulus+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0048210///Golgi vesicle fusion to target membrane+++GO:0060271///cilium assembly+++GO:0051223///regulation of protein transport+++GO:0017157///regulation of exocytosis+++GO:0032880///regulation of protein localization+++GO:0015031///protein transport+++GO:0009306///protein secretion+++GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099003///vesicle-mediated transport in synapse+++GO:0032482///Rab protein signal transduction+++GO:0043687///post-translational protein modification+++GO:0030030///cell projection organization+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006886///intracellular protein transport+++GO:0098969///neurotransmitter receptor transport to postsynaptic membrane+++GO:0007409///axonogenesis","RAB8A, member RAS oncogene family","[RAB8A_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-8A; AltName: Full=Oncogene c-mel; Flags: Precursor;+++[A0A024R7I3_HUMAN|Unreviewed]SubName: Full=RAB8A, member RAS oncogene family, isoform CRA_a {ECO:0000313|EMBL:EAW84527.1};"]
[4257,"'MGST1'",695,557,629,627,"00980///Metabolism of xenobiotics by cytochrome P450+++00480///Glutathione metabolism+++00983///Drug metabolism - other enzymes+++05204///Chemical carcinogenesis+++05200///Pathways in cancer+++05418///Fluid shear stress and atherosclerosis+++01524///Platinum drug resistance+++00982///Drug metabolism - cytochrome P450+++05225///Hepatocellular carcinoma","H00516///Cleft lip and/or cleft palate+++H00024///Prostate cancer",null,"R07023///1-nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene+++R07025///1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene+++R07026///1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene+++R09409///glutathione-S-transferase   Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH+++R07094///2-(S-glutathionyl)acetyl-chloride:glutathione 2-(S-glutathionyl)acetyltransferase   2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid+++R07091///S-(2,2-dichloro-1-hydroxy)ethyl-glutathione 2,2-dichloroacetaldehyde-lyase (glutathione-forming)   2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione+++R07116///2-bromoacetaldehyde:glutathione S-(formylmethyl)transferase   2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid+++R07070///2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene+++R07113///1,2-dibromoethane:glutathione ethylenetransferase (episulfonium-forming)   1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid+++R07084///7,8-dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene hydrolase   Benzo[a]pyrene-7,8-diol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O+++R07093///chloroacetyl-chloride:glutathione S-chloroacetyltransferase   Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid+++R07069///3,4-dihydro-3-hydroxy-4-S-glutathionyl bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene+++R07083///4,5-dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene glutathione-lyase (epoxide-forming)   Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene+++R11905///Hepatotoxins + Glutathione <=> R-S-Glutathione+++R07092///1,1-dichloroethylene-epoxide:glutathione S-(chloroepoxyethyl)transferase [2-(S-glutathionyl)acetyl-chloride-forming]   1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid+++R07002///(1R)-hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene+++R08280///4-glutathionyl cyclophosphamide hydrolase   Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O+++R03522///RX:glutathione R-transferase   RX + Glutathione <=> Halide + R-S-Glutathione+++R07004///(1S)-hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene+++R07003///(1R)-glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene+++R07100///trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase   Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid+++R07024///1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene","GO:0045177///apical part of cell+++GO:0005741///mitochondrial outer membrane+++GO:0005634///nucleus+++GO:0035577///azurophil granule membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0005778///peroxisomal membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0004602///glutathione peroxidase activity+++GO:0043295///glutathione binding+++GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding+++GO:0016740///transferase activity+++GO:0004364///glutathione transferase activity+++GO:0050220///prostaglandin-E synthase activity+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0055114///oxidation-reduction process+++GO:0098869///cellular oxidant detoxification+++GO:0032496///response to lipopolysaccharide+++GO:1901687///glutathione derivative biosynthetic process+++GO:0006805///xenobiotic metabolic process+++GO:0071449///cellular response to lipid hydroperoxide+++GO:0042493///response to drug+++GO:0001516///prostaglandin biosynthetic process+++GO:0070207///protein homotrimerization+++GO:0010243///response to organonitrogen compound+++GO:0006749///glutathione metabolic process+++GO:0033327///Leydig cell differentiation","microsomal glutathione S-transferase 1","[MGST1_HUMAN|Reviewed]RecName: Full=Microsomal glutathione S-transferase 1; Short=Microsomal GST-1; EC=2.5.1.18; AltName: Full=Microsomal GST-I;+++[A0A024RAX2_HUMAN|Unreviewed]SubName: Full=Microsomal glutathione S-transferase 1, isoform CRA_a {ECO:0000313|EMBL:EAW96369.1};+++[F5GX73_HUMAN|Unreviewed]SubName: Full=Microsomal glutathione S-transferase 1 {ECO:0000313|Ensembl:ENSP00000440443}; Flags: Fragment;+++[F5H613_HUMAN|Unreviewed]SubName: Full=Microsomal glutathione S-transferase 1 {ECO:0000313|Ensembl:ENSP00000437988};+++[F5H6X2_HUMAN|Unreviewed]SubName: Full=Microsomal glutathione S-transferase 1 {ECO:0000313|Ensembl:ENSP00000442970}; Flags: Fragment;+++[F5H760_HUMAN|Unreviewed]SubName: Full=Microsomal glutathione S-transferase 1 {ECO:0000313|Ensembl:ENSP00000442767}; Flags: Fragment;+++[F5H7F6_HUMAN|Unreviewed]SubName: Full=Microsomal glutathione S-transferase 1 {ECO:0000313|Ensembl:ENSP00000442557}; Flags: Fragment;+++[Q6LET6_HUMAN|Unreviewed]SubName: Full=MGST1 protein {ECO:0000313|EMBL:CAG28557.1}; Flags: Fragment;"]
[4286,"'MITF'",2900,2137,1756,2264.33333333333,"05200///Pathways in cancer+++05202///Transcriptional misregulation in cancer+++04916///Melanogenesis+++05218///Melanoma+++04380///Osteoclast differentiation+++04137///Mitophagy - animal","H01187///Tietz syndrome+++H00169///Ocular albinism+++H00038///Melanoma+++H00759///Waardenburg syndrome (WS)",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0070888///E-box binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0030318///melanocyte differentiation+++GO:0010628///positive regulation of gene expression+++GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway+++GO:0044336///canonical Wnt signaling pathway involved in negative regulation of apoptotic process+++GO:0030336///negative regulation of cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:2001141///regulation of RNA biosynthetic process+++GO:0045670///regulation of osteoclast differentiation+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0045165///cell fate commitment+++GO:0046849///bone remodeling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0065003///protein-containing complex assembly+++GO:0043473///pigmentation+++GO:0043010///camera-type eye development+++GO:0006959///humoral immune response+++GO:0030316///osteoclast differentiation","melanogenesis associated transcription factor","[MITF_HUMAN|Reviewed]RecName: Full=Microphthalmia-associated transcription factor; AltName: Full=Class E basic helix-loop-helix protein 32; Short=bHLHe32;+++[A0A087WXU1_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|Ensembl:ENSP00000481286};+++[A0A0A7NWS7_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|EMBL:AIZ97493.1}; Flags: Fragment;+++[A0A0H3W5T2_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|EMBL:AKK25260.2}; Flags: Fragment;+++[B4DNC7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53142, highly similar to Microphthalmia-associated transcription factor {ECO:0000313|EMBL:BAG60189.1};+++[C9J845_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|Ensembl:ENSP00000411389}; Flags: Fragment;+++[C9JBI8_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|Ensembl:ENSP00000398639}; Flags: Fragment;+++[C9K0S7_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|Ensembl:ENSP00000407620}; Flags: Fragment;+++[E9PKJ8_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor {ECO:0000313|Ensembl:ENSP00000433487};+++[Q8TF70_HUMAN|Unreviewed]SubName: Full=Microphtalmia-associated transcription factor {ECO:0000313|EMBL:BAB85121.1}; Flags: Fragment;+++[Q8WYR3_HUMAN|Unreviewed]SubName: Full=Microphthalmia-associated transcription factor isoform {ECO:0000313|EMBL:BAB83926.1}; Flags: Fragment;"]
[4293,"'MAP3K9'",1111.95,919.91,700.01,910.623333333333,"04013///MAPK signaling pathway - fly",null,"M00688///MAPK (JNK) signaling+++M00689///MAPK (p38) signaling",null,"GO:0005575///cellular_component","GO:0004713///protein tyrosine kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0004706///JUN kinase kinase kinase activity","GO:0008219///cell death+++GO:0007256///activation of JNKK activity+++GO:0016310///phosphorylation+++GO:0007257///activation of JUN kinase activity+++GO:0000186///activation of MAPKK activity+++GO:0043065///positive regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0000165///MAPK cascade+++GO:0006915///apoptotic process+++GO:0006468///protein phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation","mitogen-activated protein kinase kinase kinase 9","[M3K9_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase 9; EC=2.7.11.25; AltName: Full=Mixed lineage kinase 1;+++[A0A087WW79_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 9 {ECO:0000313|Ensembl:ENSP00000480011};+++[B4DZC4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60378, highly similar to Mitogen-activated protein kinase kinase kinase 9 {ECO:0000313|EMBL:BAG64036.1};+++[G3V347_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 9 {ECO:0000313|Ensembl:ENSP00000451038};+++[G3V4P9_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 9 {ECO:0000313|Ensembl:ENSP00000451921};+++[J3KPI6_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase {ECO:0000256|PIRNR:PIRNR000556}; EC=2.7.11.25 {ECO:0000256|PIRNR:PIRNR000556};+++[Q8NEB1_HUMAN|Unreviewed]SubName: Full=Similar to mitogen-activated protein kinase kinase kinase 9 {ECO:0000313|EMBL:AAH33197.1}; Flags: Fragment;"]
[4314,"'MMP3'",0,0,1,0.333333333333333,"05215///Prostate cancer+++04668///TNF signaling pathway+++05202///Transcriptional misregulation in cancer+++04657///IL-17 signaling pathway+++05323///Rheumatoid arthritis","H01742///Coronary artery disease",null,null,"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004222///metalloendopeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008237///metallopeptidase activity","GO:0032461///positive regulation of protein oligomerization+++GO:0030334///regulation of cell migration+++GO:0071732///cellular response to nitric oxide+++GO:0150077///regulation of neuroinflammatory response+++GO:0030574///collagen catabolic process+++GO:1903209///positive regulation of oxidative stress-induced cell death+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006508///proteolysis+++GO:0022617///extracellular matrix disassembly+++GO:0001666///response to hypoxia+++GO:0010727///negative regulation of hydrogen peroxide metabolic process","matrix metallopeptidase 3","[MMP3_HUMAN|Reviewed]RecName: Full=Stromelysin-1; Short=SL-1; EC=3.4.24.17; AltName: Full=Matrix metalloproteinase-3; Short=MMP-3; AltName: Full=Transin-1; Flags: Precursor;+++[A0A0U3J4I2_HUMAN|Unreviewed]SubName: Full=MMP3 {ECO:0000313|EMBL:ALV82540.1}; Flags: Fragment;+++[A5GZ70_HUMAN|Unreviewed]SubName: Full=Matrix metalloproteinase 3 {ECO:0000313|EMBL:ABD92797.1}; Flags: Fragment;+++[E9PKX2_HUMAN|Unreviewed]RecName: Full=Matrix metalloproteinase {ECO:0000256|RuleBase:RU364080}; EC=3.4.24.- {ECO:0000256|RuleBase:RU364080};+++[H7C139_HUMAN|Unreviewed]RecName: Full=Matrix metalloproteinase {ECO:0000256|RuleBase:RU364080}; EC=3.4.24.- {ECO:0000256|RuleBase:RU364080}; Flags: Fragment;"]
[4351,"'MPI'",1008,1084,1025,1039,"00051///Fructose and mannose metabolism+++01130///Biosynthesis of antibiotics+++00520///Amino sugar and nucleotide sugar metabolism+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways","H00118///Congenital disorders of glycosylation (CDG) type I","M00114///Ascorbate biosynthesis, plants, glucose-6P => ascorbate","R01819///D-mannose-6-phosphate aldose-ketose-isomerase   D-Mannose 6-phosphate <=> beta-D-Fructose 6-phosphate","GO:0030133///transport vesicle+++GO:0005794///Golgi apparatus+++GO:0032588///trans-Golgi network membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0008270///zinc ion binding+++GO:0004476///mannose-6-phosphate isomerase activity","GO:0006486///protein glycosylation+++GO:0009298///GDP-mannose biosynthetic process+++GO:0015031///protein transport+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0005975///carbohydrate metabolic process+++GO:0000032///cell wall mannoprotein biosynthetic process+++GO:0061611///mannose to fructose-6-phosphate metabolic process","mannose phosphate isomerase","[MPI_HUMAN|Reviewed]RecName: Full=Mannose-6-phosphate isomerase; EC=5.3.1.8; AltName: Full=Phosphohexomutase; AltName: Full=Phosphomannose isomerase; Short=PMI;+++[B4DW50_HUMAN|Unreviewed]RecName: Full=Mannose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000611}; EC=5.3.1.8 {ECO:0000256|RuleBase:RU000611};+++[F5GX71_HUMAN|Unreviewed]RecName: Full=Mannose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000611}; EC=5.3.1.8 {ECO:0000256|RuleBase:RU000611};+++[H3BPB8_HUMAN|Unreviewed]RecName: Full=Mannose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000611}; EC=5.3.1.8 {ECO:0000256|RuleBase:RU000611};+++[H3BPP3_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000455405};+++[Q8NHZ6_HUMAN|Unreviewed]SubName: Full=Mannose phosphate isomerase isoform {ECO:0000313|EMBL:AAM28199.1};"]
[4359,"'MPZ'",5,4,8,5.66666666666667,"04514///Cell adhesion molecules (CAMs)","H00264///Charcot-Marie-Tooth disease (CMT)+++H01155///Roussy-Levy syndrome",null,null,"GO:0005886///plasma membrane+++GO:0043209///myelin sheath+++GO:0016323///basolateral plasma membrane+++GO:0005968///Rab-protein geranylgeranyltransferase complex+++GO:0005887///integral component of plasma membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005764///lysosome","GO:0005092///GDP-dissociation inhibitor activity+++GO:0005096///GTPase activator activity+++GO:0004663///Rab geranylgeranyltransferase activity+++GO:0005198///structural molecule activity+++GO:0017137///Rab GTPase binding","GO:0042552///myelination+++GO:0007601///visual perception+++GO:0018344///protein geranylgeranylation+++GO:0007268///chemical synaptic transmission+++GO:0042981///regulation of apoptotic process+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0043687///post-translational protein modification+++GO:0007264///small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0043547///positive regulation of GTPase activity+++GO:0098743///cell aggregation+++GO:0043066///negative regulation of apoptotic process+++GO:0006886///intracellular protein transport+++GO:0006612///protein targeting to membrane+++GO:0050896///response to stimulus","myelin protein zero","[MYP0_HUMAN|Reviewed]RecName: Full=Myelin protein P0; AltName: Full=Myelin peripheral protein; Short=MPP; AltName: Full=Myelin protein zero; Flags: Precursor;+++[A0A0J9YWT2_HUMAN|Unreviewed]SubName: Full=Myelin protein P0 {ECO:0000313|Ensembl:ENSP00000488104}; Flags: Fragment;+++[E9PL80_HUMAN|Unreviewed]SubName: Full=Myelin protein P0 {ECO:0000313|Ensembl:ENSP00000431441};+++[Q8N917_HUMAN|Unreviewed]SubName: Full=CHM protein {ECO:0000313|EMBL:AAH65702.1}; SubName: Full=HSD-32 {ECO:0000313|EMBL:AAP15253.1}; SubName: Full=cDNA FLJ38564 fis, clone HCHON2004359 {ECO:0000313|EMBL:BAC04640.1};"]
[440345,"'NPIPB4'",3342.21,2949.41,2856.78,3049.46666666667,"04140///Autophagy - animal+++03015///mRNA surveillance pathway+++01100///Metabolic pathways+++00650///Butanoate metabolism+++04137///Mitophagy - animal",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004672///protein kinase activity+++GO:0042162///telomeric DNA binding+++GO:0046872///metal ion binding+++GO:0004674///protein serine/threonine kinase activity","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006406///mRNA export from nucleus+++GO:0032204///regulation of telomere maintenance+++GO:0006281///DNA repair+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0046777///protein autophosphorylation+++GO:0046854///phosphatidylinositol phosphorylation","nuclear pore complex interacting protein family member B4","[NPIB4_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B4;+++[A0A087WT63_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000477616};+++[C9JB18_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000339196}; Flags: Fragment;+++[E7EQW1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000429543}; Flags: Fragment;+++[F5H108_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000439732}; Flags: Fragment;+++[F5H3D4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000439166};+++[F5H5F2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000443445}; Flags: Fragment;+++[F5H8A1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000442065}; Flags: Fragment;+++[V9H0F5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAC31671.1}; Flags: Fragment;"]
[440533,"'PSG8'",1.01,2.44,0,1.15,{"$nulls":4},"GO:0005576///extracellular region","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0007565///female pregnancy+++GO:0006952///defense response+++GO:0050900///leukocyte migration","pregnancy specific beta-1-glycoprotein 8","[PSG8_HUMAN|Reviewed]RecName: Full=Pregnancy-specific beta-1-glycoprotein 8; Short=PS-beta-G-8; Short=PSBG-8; Short=Pregnancy-specific glycoprotein 8; Flags: Precursor;+++[A0A0F7CSH9_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 1 {ECO:0000313|EMBL:AKG50978.1};+++[E7ENH0_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 8 {ECO:0000313|Ensembl:ENSP00000386090};+++[M0QY44_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 1 {ECO:0000313|Ensembl:ENSP00000469575}; Flags: Fragment;+++[M0QYP3_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 8 {ECO:0000313|Ensembl:ENSP00000469979};+++[M0QZQ1_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 1 {ECO:0000313|Ensembl:ENSP00000470690}; Flags: Fragment;+++[M0R235_HUMAN|Unreviewed]SubName: Full=Pregnancy specific beta-1-glycoprotein 1, isoform CRA_e {ECO:0000313|EMBL:EAW57158.1}; SubName: Full=Pregnancy-specific beta-1-glycoprotein 1 {ECO:0000313|Ensembl:ENSP00000472284};+++[O75237_HUMAN|Unreviewed]SubName: Full=PSGIIA-c {ECO:0000313|EMBL:AAC25487.1}; SubName: Full=Pregnancy specific beta-1-glycoprotein 1, isoform CRA_g {ECO:0000313|EMBL:EAW57160.1};+++[Q15106_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1 glycoprotein {ECO:0000313|EMBL:AAA60025.1}; Flags: Fragment;+++[Q15107_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1 glycoprotein {ECO:0000313|EMBL:AAA60027.1}; Flags: Fragment;+++[Q15108_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1 glycoprotein {ECO:0000313|EMBL:AAA60026.1}; Flags: Fragment;+++[Q15230_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1 glycoprotein {ECO:0000313|EMBL:AAA60199.1}; Flags: Fragment;+++[Q15402_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific protein {ECO:0000313|EMBL:AAA67524.1}; Flags: Fragment;+++[Q9UPK8_HUMAN|Unreviewed]SubName: Full=PSGIIA-a {ECO:0000313|EMBL:AAC25485.1};+++[Q9UPK9_HUMAN|Unreviewed]SubName: Full=PSGIIA-b {ECO:0000313|EMBL:AAC25486.1};"]
[441151,"'TMEM151B'",18,35,21,24.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"transmembrane protein 151B","[T151B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 151B; AltName: Full=Transmembrane protein 193;"]
[441425,"'ANKRD20A3'",0,7.39,0,2.46333333333333,{"$nulls":7},"ankyrin repeat domain 20 family member A3","[A20A3_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 20A3;+++[A0A087WY83_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 20A3 {ECO:0000313|Ensembl:ENSP00000481596};+++[B2RTT7_HUMAN|Unreviewed]SubName: Full=ANKRD20A2 protein {ECO:0000313|EMBL:AAI40810.1};"]
[4437,"'MSH3'",368,325,285.99,326.33,"01524///Platinum drug resistance+++03430///Mismatch repair+++05210///Colorectal cancer+++05200///Pathways in cancer","H00020///Colorectal cancer",null,null,"GO:0005654///nucleoplasm+++GO:0032300///mismatch repair complex+++GO:0005634///nucleus+++GO:0032302///MutSbeta complex+++GO:0016020///membrane","GO:0008094///DNA-dependent ATPase activity+++GO:0000166///nucleotide binding+++GO:0030983///mismatched DNA binding+++GO:0005515///protein binding+++GO:0003697///single-stranded DNA binding+++GO:0032181///dinucleotide repeat insertion binding+++GO:0032139///dinucleotide insertion or deletion binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0032142///single guanine insertion binding+++GO:0019899///enzyme binding+++GO:0000406///double-strand/single-strand DNA junction binding+++GO:0032137///guanine/thymine mispair binding+++GO:0032143///single thymine insertion binding+++GO:0005524///ATP binding+++GO:0032357///oxidized purine DNA binding+++GO:0003684///damaged DNA binding","GO:0051096///positive regulation of helicase activity+++GO:0043570///maintenance of DNA repeat elements+++GO:0006312///mitotic recombination+++GO:0006298///mismatch repair+++GO:0007131///reciprocal meiotic recombination+++GO:0043111///replication fork arrest+++GO:0045910///negative regulation of DNA recombination+++GO:0000710///meiotic mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000735///removal of nonhomologous ends+++GO:0006281///DNA repair","mutS homolog 3","[MSH3_HUMAN|Reviewed]RecName: Full=DNA mismatch repair protein Msh3; Short=hMSH3; AltName: Full=Divergent upstream protein; Short=DUP; AltName: Full=Mismatch repair protein 1; Short=MRP1;"]
[445582,"'POTEE'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0072562///blood microparticle+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0003674///molecular_function","GO:0021762///substantia nigra development+++GO:0001895///retina homeostasis","POTE ankyrin domain family member E","[POTEE_HUMAN|Reviewed]RecName: Full=POTE ankyrin domain family member E; AltName: Full=ANKRD26-like family C member 1A; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 2; Short=POTE-2;+++[A0A087X067_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member E {ECO:0000313|Ensembl:ENSP00000483137};"]
[4521,"'NUDT1'",49,56,61,55.3333333333333,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005615///extracellular space+++GO:0005759///mitochondrial matrix+++GO:0001669///acrosomal vesicle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0008413///8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity+++GO:0044713///2-hydroxy-adenosine triphosphate pyrophosphatase activity+++GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0044714///2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity+++GO:0047693///ATP diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0035539///8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity+++GO:0030515///snoRNA binding+++GO:0003924///GTPase activity+++GO:0036219///GTP diphosphatase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0046686///response to cadmium ion+++GO:0006281///DNA repair+++GO:0006979///response to oxidative stress+++GO:0006195///purine nucleotide catabolic process+++GO:0008584///male gonad development+++GO:0034656///nucleobase-containing small molecule catabolic process+++GO:0006203///dGTP catabolic process+++GO:0007568///aging+++GO:0046061///dATP catabolic process+++GO:0042262///DNA protection","nudix hydrolase 1","[8ODP_HUMAN|Reviewed]RecName: Full=7,8-dihydro-8-oxoguanine triphosphatase; EC=3.6.1.55 {ECO:0000269|PubMed:10373420, ECO:0000269|PubMed:10608900, ECO:0000269|PubMed:11139615, ECO:0000269|PubMed:11756418, ECO:0000269|PubMed:22556419, ECO:0000269|PubMed:7782328, ECO:0000269|PubMed:8226881}; AltName: Full=2-hydroxy-dATP diphosphatase; EC=3.6.1.56 {ECO:0000269|PubMed:10373420, ECO:0000269|PubMed:11139615, ECO:0000269|PubMed:11756418, ECO:0000269|PubMed:12857738, ECO:0000269|PubMed:24695224}; AltName: Full=8-oxo-dGTPase; AltName: Full=Nucleoside diphosphate-linked moiety X motif 1; Short=Nudix motif 1; Flags: Precursor;+++[A0A024R819_HUMAN|Unreviewed]SubName: Full=Nudix (Nucleoside diphosphate linked moiety X)-type motif 1, isoform CRA_a {ECO:0000313|EMBL:EAW87231.1};+++[A0A024R858_HUMAN|Unreviewed]SubName: Full=Nudix (Nucleoside diphosphate linked moiety X)-type motif 1, isoform CRA_b {ECO:0000313|EMBL:EAW87230.1};+++[C9J361_HUMAN|Unreviewed]SubName: Full=7,8-dihydro-8-oxoguanine triphosphatase {ECO:0000313|Ensembl:ENSP00000405334}; Flags: Fragment;"]
[4584,"'MUC3A'",43,53,61,52.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0005796///Golgi lumen","GO:0030197///extracellular matrix constituent, lubricant activity+++GO:0005201///extracellular matrix structural constituent","GO:0016266///O-glycan processing+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","mucin 3A, cell surface associated","[MUC3A_HUMAN|Reviewed]RecName: Full=Mucin-3A {ECO:0000305}; Short=MUC-3A {ECO:0000305}; AltName: Full=Intestinal mucin-3A {ECO:0000305|PubMed:12958310}; Flags: Precursor;+++[Q9H3Q6_HUMAN|Unreviewed]SubName: Full=Intestinal mucin {ECO:0000313|EMBL:BAB12118.1}; Flags: Fragment;"]
[4610,"'MYCL'",84,98,81,87.6666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045607///regulation of inner ear auditory receptor cell differentiation","MYCL proto-oncogene, bHLH transcription factor","[MYCL_HUMAN|Reviewed]RecName: Full=Protein L-Myc; AltName: Full=Class E basic helix-loop-helix protein 38; Short=bHLHe38; AltName: Full=Protein L-Myc-1; AltName: Full=V-myc myelocytomatosis viral oncogene homolog;+++[A0A0A0N0L0_HUMAN|Unreviewed]SubName: Full=L-Myc isoform 4 {ECO:0000313|EMBL:AER93388.1};+++[E9PQS5_HUMAN|Unreviewed]SubName: Full=Protein L-Myc {ECO:0000313|Ensembl:ENSP00000434375}; Flags: Fragment;+++[Q86YL9_HUMAN|Unreviewed]SubName: Full=L-myc protein {ECO:0000313|EMBL:AAO38672.1}; Flags: Fragment;"]
[4633,"'MYL2'",0,7,0,2.33333333333333,"04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04371///Apelin signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04810///Regulation of actin cytoskeleton+++04260///Cardiac muscle contraction+++05410///Hypertrophic cardiomyopathy (HCM)+++04261///Adrenergic signaling in cardiomyocytes+++04530///Tight junction","H00292///Hypertrophic cardiomyopathy (HCM)",null,null,"GO:0005737///cytoplasm+++GO:0030016///myofibril+++GO:0030017///sarcomere+++GO:0097512///cardiac myofibril+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0016459///myosin complex+++GO:0031672///A band","GO:0032036///myosin heavy chain binding+++GO:0003785///actin monomer binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle","GO:0002026///regulation of the force of heart contraction+++GO:0030049///muscle filament sliding+++GO:0030308///negative regulation of cell growth+++GO:0048747///muscle fiber development+++GO:0009791///post-embryonic development+++GO:0042694///muscle cell fate specification+++GO:0003007///heart morphogenesis+++GO:0055003///cardiac myofibril assembly+++GO:0060047///heart contraction+++GO:0007507///heart development+++GO:0060048///cardiac muscle contraction+++GO:0098735///positive regulation of the force of heart contraction+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0006942///regulation of striated muscle contraction","myosin light chain 2","[MLRV_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 2, ventricular/cardiac muscle isoform {ECO:0000305}; Short=MLC-2 {ECO:0000250|UniProtKB:P08733}; Short=MLC-2v; AltName: Full=Cardiac myosin light chain 2 {ECO:0000303|Ref.3}; AltName: Full=Myosin light chain 2, slow skeletal/ventricular muscle isoform {ECO:0000250|UniProtKB:Q7M2V4}; Short=MLC-2s/v {ECO:0000250|UniProtKB:Q7M2V4}; AltName: Full=Ventricular myosin light chain 2 {ECO:0000303|PubMed:2704627};+++[A0A191TDH3_HUMAN|Unreviewed]SubName: Full=Myosin light chain-2 {ECO:0000313|EMBL:ANI86418.1}; Flags: Fragment;+++[G3V1V8_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 2, ventricular/cardiac muscle isoform {ECO:0000313|Ensembl:ENSP00000447154}; SubName: Full=Myosin, light polypeptide 2, regulatory, cardiac, slow, isoform CRA_b {ECO:0000313|EMBL:EAW97944.1};+++[Q6IB42_HUMAN|Unreviewed]SubName: Full=MYL2 protein {ECO:0000313|EMBL:CAG33243.1}; SubName: Full=Myosin, light polypeptide 2, regulatory, cardiac, slow, isoform CRA_a {ECO:0000313|EMBL:EAW97943.1}; SubName: Full=cDNA, FLJ92288, highly similar to Homo sapiens myosin, light polypeptide 2, regulatory, cardiac, slow (MYL2), mRNA {ECO:0000313|EMBL:BAG34951.1};"]
[4637,"'MYL6'",7666,9656,10168,9163.33333333333,"04270///Vascular smooth muscle contraction+++04921///Oxytocin signaling pathway+++04530///Tight junction",{"$nulls":3},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005903///brush border+++GO:0016459///myosin complex+++GO:0016461///unconventional myosin complex+++GO:0031982///vesicle","GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0030898///actin-dependent ATPase activity+++GO:0003774///motor activity+++GO:0008307///structural constituent of muscle","GO:0007519///skeletal muscle tissue development+++GO:0030049///muscle filament sliding+++GO:0006936///muscle contraction","myosin light chain 6","[MYL6_HUMAN|Reviewed]RecName: Full=Myosin light polypeptide 6; AltName: Full=17 kDa myosin light chain; Short=LC17; AltName: Full=Myosin light chain 3; Short=MLC-3; AltName: Full=Myosin light chain alkali 3; Short=Myosin light chain A3; AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6;+++[B7Z6Z4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56329, highly similar to Myosin light polypeptide 6 {ECO:0000313|EMBL:BAH13430.1};+++[F8VPF3_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000450116}; Flags: Fragment;+++[F8VXL3_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000449086};+++[F8VZU9_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000446640};+++[F8W180_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000446709};+++[F8W1R7_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000446687};+++[G3V1V0_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000446721}; SubName: Full=Myosin, light polypeptide 6, alkali, smooth muscle and non-muscle, isoform CRA_c {ECO:0000313|EMBL:EAW96901.1};+++[G3V1Y7_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000448859}; SubName: Full=Myosin, light polypeptide 6, alkali, smooth muscle and non-muscle, isoform CRA_d {ECO:0000313|EMBL:EAW96902.1};+++[G8JLA2_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000293422};+++[H0YI43_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000448457}; Flags: Fragment;+++[J3KND3_HUMAN|Unreviewed]SubName: Full=Myosin light polypeptide 6 {ECO:0000313|Ensembl:ENSP00000301540};+++[Q6IBG5_HUMAN|Unreviewed]SubName: Full=MYL6 protein {ECO:0000313|EMBL:CAG33120.1};"]
[4674,"'NAP1L2'",90,57,44,63.6666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0042393///histone binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding","GO:0035066///positive regulation of histone acetylation+++GO:0071442///positive regulation of histone H3-K14 acetylation+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:0006334///nucleosome assembly+++GO:2000035///regulation of stem cell division+++GO:0045666///positive regulation of neuron differentiation","nucleosome assembly protein 1 like 2","[NP1L2_HUMAN|Reviewed]RecName: Full=Nucleosome assembly protein 1-like 2; AltName: Full=Brain-specific protein, X-linked;+++[L8E8P2_HUMAN|Unreviewed]SubName: Full=Alternative protein NAP1L2 {ECO:0000313|EMBL:CCQ43675.1};"]
[4675,"'NAP1L3'",330,305,249,294.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding","GO:0006334///nucleosome assembly","nucleosome assembly protein 1 like 3","[NP1L3_HUMAN|Reviewed]RecName: Full=Nucleosome assembly protein 1-like 3;+++[L0R6L2_HUMAN|Unreviewed]SubName: Full=Alternative protein NAP1L3 {ECO:0000313|EMBL:CCO13777.1};+++[Q8IYV1_HUMAN|Unreviewed]SubName: Full=Nucleosome assembly protein 1-like 3 {ECO:0000313|EMBL:AAH34954.1};+++[V9GYL6_HUMAN|Unreviewed]SubName: Full=Nucleosome assembly protein 1-like 3 {ECO:0000313|Ensembl:ENSP00000476891};"]
[4694,"'NDUFA1'",231,258,339,276,"01100///Metabolic pathways+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04723///Retrograde endocannabinoid signaling+++05012///Parkinson's disease+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++05016///Huntington's disease","H00473///Mitochondrial complex I deficiency","M00146///NADH dehydrogenase (ubiquinone) 1 alpha subcomplex",null,"GO:0005829///cytosol+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070469///respiratory chain","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0055114///oxidation-reduction process","NADH:ubiquinone oxidoreductase subunit A1","[NDUA1_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; AltName: Full=Complex I-MWFE; Short=CI-MWFE; AltName: Full=NADH-ubiquinone oxidoreductase MWFE subunit;+++[Q6IBB5_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase (Ubiquinone) 1 alpha subcomplex, 1, 7.5kDa {ECO:0000313|EMBL:EAW89840.1}; SubName: Full=NADH oxidoreductase subunit MWFE {ECO:0000313|EMBL:BAG70118.1}; SubName: Full=ZNF183 protein {ECO:0000313|EMBL:CAG33170.1};"]
[471,"'ATIC'",888,934,1002,941.333333333333,"01523///Antifolate resistance+++01100///Metabolic pathways+++00230///Purine metabolism+++01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites+++00670///One carbon pool by folate","H00966///AICA-ribosiduria","M00048///Inosine monophosphate biosynthesis, PRPP + glutamine => IMP","R04560///10-Formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase   10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide+++R01127///IMP 1,2-hydrolase (decyclizing)   IMP + H2O <=> 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0016740///transferase activity+++GO:0004643///phosphoribosylaminoimidazolecarboxamide formyltransferase activity+++GO:0016787///hydrolase activity+++GO:0045296///cadherin binding+++GO:0003937///IMP cyclohydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0003824///catalytic activity","GO:0021987///cerebral cortex development+++GO:0003360///brainstem development+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0021549///cerebellum development+++GO:0009259///ribonucleotide metabolic process+++GO:0009116///nucleoside metabolic process+++GO:0008152///metabolic process+++GO:0046654///tetrahydrofolate biosynthetic process+++GO:0031100///animal organ regeneration+++GO:0010035///response to inorganic substance+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0046452///dihydrofolate metabolic process+++GO:0098761///cellular response to interleukin-7","5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase","[PUR9_HUMAN|Reviewed]RecName: Full=Bifunctional purine biosynthesis protein PURH; Includes: RecName: Full=Phosphoribosylaminoimidazolecarboxamide formyltransferase; EC=2.1.2.3; AltName: Full=5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AltName: Full=AICAR transformylase; Includes: RecName: Full=IMP cyclohydrolase; EC=3.5.4.10; AltName: Full=ATIC; AltName: Full=IMP synthase; AltName: Full=Inosinicase; Contains: RecName: Full=Bifunctional purine biosynthesis protein PURH, N-terminally processed;+++[C9JLK0_HUMAN|Unreviewed]SubName: Full=Bifunctional purine biosynthesis protein PURH {ECO:0000313|Ensembl:ENSP00000402393}; Flags: Fragment;+++[F2Z3E8_HUMAN|Unreviewed]SubName: Full=Bifunctional purine biosynthesis protein PURH {ECO:0000313|Ensembl:ENSP00000406792};+++[F8WEF0_HUMAN|Unreviewed]SubName: Full=Bifunctional purine biosynthesis protein PURH {ECO:0000313|Ensembl:ENSP00000388675};+++[H7C1S2_HUMAN|Unreviewed]SubName: Full=Bifunctional purine biosynthesis protein PURH {ECO:0000313|Ensembl:ENSP00000401936}; Flags: Fragment;+++[V9HWH7_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 70p {ECO:0000313|EMBL:ACJ13708.1};"]
[4726,"'NDUFS6'",489,535,640,554.666666666667,"04723///Retrograde endocannabinoid signaling+++01100///Metabolic pathways+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease+++05016///Huntington's disease+++04714///Thermogenesis+++00190///Oxidative phosphorylation","H00473///Mitochondrial complex I deficiency","M00143///NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria",null,"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0070469///respiratory chain+++GO:0005747///mitochondrial respiratory chain complex I","GO:0009055///electron transfer activity+++GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0035264///multicellular organism growth+++GO:0010259///multicellular organism aging+++GO:0055114///oxidation-reduction process+++GO:0061458///reproductive system development+++GO:0072358///cardiovascular system development+++GO:0006631///fatty acid metabolic process+++GO:0022904///respiratory electron transport chain+++GO:0070584///mitochondrion morphogenesis+++GO:0006936///muscle contraction+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly","NADH:ubiquinone oxidoreductase subunit S6","[NDUS6_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; AltName: Full=Complex I-13kD-A; Short=CI-13kD-A; AltName: Full=NADH-ubiquinone oxidoreductase 13 kDa-A subunit; Flags: Precursor;+++[D6RBT3_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000422557};+++[Q6IBC4_HUMAN|Unreviewed]RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial {ECO:0000256|PIRNR:PIRNR016564};"]
[4744,"'NEFH'",404,561,524,496.333333333333,"05014///Amyotrophic lateral sclerosis (ALS)","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0097418///neurofibrillary tangle+++GO:0043209///myelin sheath+++GO:0005882///intermediate filament+++GO:0005856///cytoskeleton+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005883///neurofilament+++GO:0099160///postsynaptic intermediate filament cytoskeleton","GO:0030674///protein binding, bridging+++GO:0019894///kinesin binding+++GO:0008017///microtubule binding+++GO:0099184///structural constituent of postsynaptic intermediate filament cytoskeleton+++GO:0005200///structural constituent of cytoskeleton+++GO:0070840///dynein complex binding+++GO:0019901///protein kinase binding+++GO:0005198///structural molecule activity","GO:0045104///intermediate filament cytoskeleton organization+++GO:0048936///peripheral nervous system neuron axonogenesis+++GO:0000226///microtubule cytoskeleton organization+++GO:0045110///intermediate filament bundle assembly+++GO:1902513///regulation of organelle transport along microtubule+++GO:0060052///neurofilament cytoskeleton organization+++GO:0033693///neurofilament bundle assembly+++GO:0007409///axonogenesis+++GO:0030031///cell projection assembly+++GO:0099185///postsynaptic intermediate filament cytoskeleton organization+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0061564///axon development","neurofilament heavy","[NFH_HUMAN|Reviewed]RecName: Full=Neurofilament heavy polypeptide; Short=NF-H; AltName: Full=200 kDa neurofilament protein; AltName: Full=Neurofilament triplet H protein;+++[Q16070_HUMAN|Unreviewed]SubName: Full=Neurofilament heavy subunit {ECO:0000313|EMBL:AAB28609.1}; Flags: Fragment;"]
[4776,"'NFATC4'",275,277,344,298.666666666667,"05166///HTLV-I infection+++04360///Axon guidance+++04218///Cellular senescence+++05161///Hepatitis B+++04310///Wnt signaling pathway+++04022///cGMP-PKG signaling pathway+++04921///Oxytocin signaling pathway+++05163///Human cytomegalovirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04625///C-type lectin receptor signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0016607///nuclear speck+++GO:0005829///cytosol+++GO:0044798///nuclear transcription factor complex+++GO:0005737///cytoplasm","GO:0003713///transcription coactivator activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0003682///chromatin binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0006954///inflammatory response+++GO:0032091///negative regulation of protein binding+++GO:0007507///heart development+++GO:0048167///regulation of synaptic plasticity+++GO:2000297///negative regulation of synapse maturation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0050774///negative regulation of dendrite morphogenesis+++GO:1904637///cellular response to ionomycin+++GO:0035562///negative regulation of chromatin binding+++GO:0006366///transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0034644///cellular response to UV+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0071285///cellular response to lithium ion+++GO:0001816///cytokine production+++GO:0055001///muscle cell development+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0051145///smooth muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045333///cellular respiration+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0033173///calcineurin-NFAT signaling cascade","nuclear factor of activated T cells 4","[NFAC4_HUMAN|Reviewed]RecName: Full=Nuclear factor of activated T-cells, cytoplasmic 4; Short=NF-ATc4; Short=NFATc4; AltName: Full=T-cell transcription factor NFAT3; Short=NF-AT3;+++[G3V4K1_HUMAN|Unreviewed]SubName: Full=Nuclear factor of-activated T-cells, cytoplasmic 4 {ECO:0000313|Ensembl:ENSP00000451853}; Flags: Fragment;+++[G3V4U6_HUMAN|Unreviewed]SubName: Full=Nuclear factor of-activated T-cells, cytoplasmic 4 {ECO:0000313|Ensembl:ENSP00000451992}; Flags: Fragment;+++[G3V5H0_HUMAN|Unreviewed]SubName: Full=Nuclear factor of-activated T-cells, cytoplasmic 4 {ECO:0000313|Ensembl:ENSP00000452352}; Flags: Fragment;+++[L0R8A8_HUMAN|Unreviewed]SubName: Full=Alternative protein NFATC4 {ECO:0000313|EMBL:CCO13781.1};"]
[4794,"'NFKBIE'",136,123,135,131.333333333333,"04659///Th17 cell differentiation+++04920///Adipocytokine signaling pathway+++04660///T cell receptor signaling pathway+++04658///Th1 and Th2 cell differentiation+++04722///Neurotrophin signaling pathway+++04662///B cell receptor signaling pathway+++05169///Epstein-Barr virus infection","H00007///Hodgkin lymphoma",null,null,"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0001650///fibrillar center","GO:0005515///protein binding","GO:0042942///D-serine transport+++GO:0042994///cytoplasmic sequestering of transcription factor","NFKB inhibitor epsilon","[IKBE_HUMAN|Reviewed]RecName: Full=NF-kappa-B inhibitor epsilon; Short=NF-kappa-BIE; AltName: Full=I-kappa-B-epsilon; Short=IkB-E; Short=IkB-epsilon; Short=IkappaBepsilon;+++[A0A024RD24_HUMAN|Unreviewed]SubName: Full=Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, isoform CRA_a {ECO:0000313|EMBL:EAX04263.1};+++[H0Y4W4_HUMAN|Unreviewed]SubName: Full=NF-kappa-B inhibitor epsilon {ECO:0000313|Ensembl:ENSP00000394658}; Flags: Fragment;+++[H3BNC2_HUMAN|Unreviewed]SubName: Full=NF-kappa-B inhibitor epsilon {ECO:0000313|Ensembl:ENSP00000454778};+++[Q7LC14_HUMAN|Unreviewed]SubName: Full=NFKBIE protein {ECO:0000313|EMBL:AAM27002.1}; SubName: Full=cDNA FLJ61640, highly similar to NF-kappa-B inhibitor epsilon {ECO:0000313|EMBL:BAH13464.1};+++[Q96F31_HUMAN|Unreviewed]SubName: Full=NFKBIE protein {ECO:0000313|EMBL:AAH11676.2}; Flags: Fragment;"]
[4817,"'NIT1'",360,355,406,373.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm","GO:0000257///nitrilase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0016787///hydrolase activity","GO:0006807///nitrogen compound metabolic process+++GO:0008150///biological_process","nitrilase 1","[NIT1_HUMAN|Reviewed]RecName: Full=Deaminated glutathione amidase; Short=dGSH amidase; EC=3.5.1.- {ECO:0000250|UniProtKB:Q8VDK1}; AltName: Full=Nitrilase homolog 1; Flags: Precursor;+++[B7Z410_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50791, highly similar to Nitrilase homolog 1 {ECO:0000313|EMBL:BAH12396.1};"]
[4843,"'NOS2'",5,3,5,4.33333333333333,"05222///Small cell lung cancer+++00330///Arginine and proline metabolism+++05200///Pathways in cancer+++04146///Peroxisome+++04066///HIF-1 signaling pathway+++05145///Toxoplasmosis+++05146///Amoebiasis+++04926///Relaxin signaling pathway+++04371///Apelin signaling pathway+++04020///Calcium signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++01100///Metabolic pathways+++05140///Leishmaniasis+++05132///Salmonella infection+++01110///Biosynthesis of secondary metabolites+++05133///Pertussis+++00220///Arginine biosynthesis+++05152///Tuberculosis","H00017///Esophageal cancer",null,"R00111///N-(omega)-Hydroxyarginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)   NADPH + 2 N(omega)-Hydroxyarginine + 2 Oxygen + H+ <=> NADP+ + 2 Nitric oxide + 2 L-Citrulline + 2 H2O+++R00558///L-arginine,NADPH:oxygen oxidoreductase (N-(omega)-hydroxyarginine-forming)   L-Arginine + Oxygen + NADPH + H+ <=> N(omega)-Hydroxyarginine + NADP+ + H2O+++R00557///L-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)   2 L-Arginine + 4 Oxygen + 3 NADPH + 3 H+ <=> 2 Nitric oxide + 2 L-Citrulline + 3 NADP+ + 4 H2O","GO:0048471///perinuclear region of cytoplasm+++GO:0005622///intracellular+++GO:0005777///peroxisome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030863///cortical cytoskeleton+++GO:0005737///cytoplasm+++GO:0005782///peroxisomal matrix","GO:0005516///calmodulin binding+++GO:0050661///NADP binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0020037///heme binding+++GO:0003958///NADPH-hemoprotein reductase activity+++GO:0042803///protein homodimerization activity+++GO:0034618///arginine binding+++GO:0004517///nitric-oxide synthase activity+++GO:0046872///metal ion binding+++GO:0034617///tetrahydrobiopterin binding+++GO:0010181///FMN binding+++GO:0005102///signaling receptor binding","GO:0002227///innate immune response in mucosa+++GO:0035690///cellular response to drug+++GO:0018119///peptidyl-cysteine S-nitrosylation+++GO:0072606///interleukin-8 secretion+++GO:0001666///response to hypoxia+++GO:0009617///response to bacterium+++GO:0001912///positive regulation of leukocyte mediated cytotoxicity+++GO:0006527///arginine catabolic process+++GO:0071346///cellular response to interferon-gamma+++GO:0007623///circadian rhythm+++GO:0006625///protein targeting to peroxisome+++GO:0097755///positive regulation of blood vessel diameter+++GO:0050796///regulation of insulin secretion+++GO:0006809///nitric oxide biosynthetic process+++GO:0031284///positive regulation of guanylate cyclase activity+++GO:0050829///defense response to Gram-negative bacterium+++GO:0045454///cell redox homeostasis+++GO:0042742///defense response to bacterium+++GO:0019221///cytokine-mediated signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0032310///prostaglandin secretion+++GO:0051712///positive regulation of killing of cells of other organism+++GO:0042177///negative regulation of protein catabolic process+++GO:0007263///nitric oxide mediated signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0072604///interleukin-6 secretion+++GO:0045776///negative regulation of blood pressure+++GO:1900015///regulation of cytokine production involved in inflammatory response+++GO:0010629///negative regulation of gene expression+++GO:0006801///superoxide metabolic process+++GO:0043457///regulation of cellular respiration","nitric oxide synthase 2","[NOS2_HUMAN|Reviewed]RecName: Full=Nitric oxide synthase, inducible; EC=1.14.13.39; AltName: Full=Hepatocyte NOS; Short=HEP-NOS; AltName: Full=Inducible NO synthase; Short=Inducible NOS; Short=iNOS; AltName: Full=NOS type II; AltName: Full=Peptidyl-cysteine S-nitrosylase NOS2;+++[Q3Y9M1_HUMAN|Unreviewed]SubName: Full=Inducible nitric oxidase synthase {ECO:0000313|EMBL:AAZ76745.1}; Flags: Fragment;"]
[4858,"'NOVA2'",133,206,194,177.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0051252///regulation of RNA metabolic process+++GO:0000398///mRNA splicing, via spliceosome+++GO:0120163///negative regulation of cold-induced thermogenesis","NOVA alternative splicing regulator 2","[NOVA2_HUMAN|Reviewed]RecName: Full=RNA-binding protein Nova-2; AltName: Full=Astrocytic NOVA1-like RNA-binding protein; AltName: Full=Neuro-oncological ventral antigen 2;+++[M0R1A0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein Nova-2 {ECO:0000313|Ensembl:ENSP00000471736}; Flags: Fragment;+++[Q9HDB7_HUMAN|Unreviewed]SubName: Full=NOVA2 [amino acids 1-28] {ECO:0000313|EMBL:AAF98365.1}; Flags: Fragment;"]
[4891,"'SLC11A2'",476,581,501,519.333333333333,"04216///Ferroptosis+++04142///Lysosome+++04978///Mineral absorption","H01196///Hypochromic microcytic anemia",null,null,"GO:1903561///extracellular vesicle+++GO:0005765///lysosomal membrane+++GO:0005887///integral component of plasma membrane+++GO:0031902///late endosome membrane+++GO:0005773///vacuole+++GO:0045177///apical part of cell+++GO:0005802///trans-Golgi network+++GO:0045178///basal part of cell+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0005770///late endosome+++GO:0005768///endosome+++GO:0005739///mitochondrion+++GO:0005764///lysosome+++GO:0005741///mitochondrial outer membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005769///early endosome+++GO:0010008///endosome membrane+++GO:0070826///paraferritin complex+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0031526///brush border membrane+++GO:0055037///recycling endosome+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0070835///chromium ion transmembrane transporter activity+++GO:0005384///manganese ion transmembrane transporter activity+++GO:0022890///inorganic cation transmembrane transporter activity+++GO:0015093///ferrous iron transmembrane transporter activity+++GO:0005381///iron ion transmembrane transporter activity+++GO:0046873///metal ion transmembrane transporter activity+++GO:0046870///cadmium ion binding+++GO:0015099///nickel cation transmembrane transporter activity+++GO:0016151///nickel cation binding+++GO:0046915///transition metal ion transmembrane transporter activity+++GO:0005507///copper ion binding+++GO:0005375///copper ion transmembrane transporter activity+++GO:0015085///calcium ion transmembrane transporter activity+++GO:0005506///iron ion binding+++GO:0015295///solute:proton symporter activity+++GO:0030145///manganese ion binding+++GO:1905394///retromer complex binding+++GO:0015094///lead ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0015100///vanadium ion transmembrane transporter activity+++GO:0015086///cadmium ion transmembrane transporter activity+++GO:0050897///cobalt ion binding+++GO:0005385///zinc ion transmembrane transporter activity+++GO:0015087///cobalt ion transmembrane transporter activity","GO:1902600///proton transmembrane transport+++GO:0070574///cadmium ion transmembrane transport+++GO:0034599///cellular response to oxidative stress+++GO:0006826///iron ion transport+++GO:0007611///learning or memory+++GO:0071421///manganese ion transmembrane transport+++GO:0015676///vanadium ion transport+++GO:0035444///nickel cation transmembrane transport+++GO:0006824///cobalt ion transport+++GO:0015675///nickel cation transport+++GO:0034755///iron ion transmembrane transport+++GO:0048813///dendrite morphogenesis+++GO:0006828///manganese ion transport+++GO:0010039///response to iron ion+++GO:0006778///porphyrin-containing compound metabolic process+++GO:0015692///lead ion transport+++GO:0033212///iron assimilation+++GO:0035434///copper ion transmembrane transport+++GO:0098655///cation transmembrane transport+++GO:0003032///detection of oxygen+++GO:0071577///zinc ion transmembrane transport+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006825///copper ion transport+++GO:0055072///iron ion homeostasis+++GO:0060586///multicellular organismal iron ion homeostasis+++GO:0072511///divalent inorganic cation transport+++GO:0001666///response to hypoxia+++GO:0006879///cellular iron ion homeostasis+++GO:0006811///ion transport+++GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0048821///erythrocyte development+++GO:0030001///metal ion transport+++GO:0006783///heme biosynthetic process+++GO:0070588///calcium ion transmembrane transport","solute carrier family 11 member 2","[NRAM2_HUMAN|Reviewed]RecName: Full=Natural resistance-associated macrophage protein 2; Short=NRAMP 2; AltName: Full=Divalent cation transporter 1; AltName: Full=Divalent metal transporter 1; Short=DMT-1; AltName: Full=Solute carrier family 11 member 2;+++[A0A0A1E835_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|EMBL:AIY26915.1}; Flags: Fragment;+++[A0A0A1EL53_HUMAN|Unreviewed]SubName: Full=Solute carrier family 11 member 2 {ECO:0000313|EMBL:AIY30320.1}; Flags: Fragment;+++[A0A0H3W5I8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 11 member 2 {ECO:0000313|EMBL:AKK25337.1}; Flags: Fragment;+++[A0A0H3W5U4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 11 member 2 {ECO:0000313|EMBL:AKK25336.1}; Flags: Fragment;+++[A0A0X8GKR4_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 isoform 2 {ECO:0000313|EMBL:AMC33105.1}; SubName: Full=Solute carrier family 11 (Proton-coupled divalent metal ion transporters), member 2, isoform CRA_b {ECO:0000313|EMBL:EAW58160.1};+++[A0A2R8Y4F9_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000494001};+++[A0A2R8Y5L1_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000494619}; Flags: Fragment;+++[A0A2R8Y5Q7_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000494744}; Flags: Fragment;+++[A0A2R8YD71_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000493633};+++[A0A2R8YDL2_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000494696};+++[B3KY44_HUMAN|Unreviewed]SubName: Full=Solute carrier family 11 (Proton-coupled divalent metal ion transporters), member 2, isoform CRA_c {ECO:0000313|EMBL:EAW58161.1}; SubName: Full=cDNA FLJ46799 fis, clone TRACH3031678, highly similar to Natural resistance-associated macrophage protein 2 {ECO:0000313|EMBL:BAG54706.1};+++[F8VR36_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000450389}; Flags: Fragment;+++[F8VRL7_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000448501};+++[F8VWB0_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000449209}; Flags: Fragment;+++[F8W154_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000447102}; Flags: Fragment;+++[F8W1C0_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000446984}; Flags: Fragment;+++[F8W1D8_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000446653};+++[F8W1F2_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000447482}; Flags: Fragment;+++[F8W1P7_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000446914};+++[H0YIV3_HUMAN|Unreviewed]SubName: Full=Natural resistance-associated macrophage protein 2 {ECO:0000313|Ensembl:ENSP00000450227}; Flags: Fragment;"]
[4904,"'YBX1'",12609,13694,13785,13362.6666666667,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0031965///nuclear membrane+++GO:0010494///cytoplasmic stress granule+++GO:0005689///U12-type spliceosomal complex+++GO:0005634///nucleus+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0051020///GTPase binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0051781///positive regulation of cell division+++GO:1903608///protein localization to cytoplasmic stress granule+++GO:0008380///RNA splicing+++GO:0007219///Notch signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II","Y-box binding protein 1","[YBOX1_HUMAN|Reviewed]RecName: Full=Nuclease-sensitive element-binding protein 1; AltName: Full=CCAAT-binding transcription factor I subunit A; Short=CBF-A; AltName: Full=DNA-binding protein B; Short=DBPB; AltName: Full=Enhancer factor I subunit A; Short=EFI-A; AltName: Full=Y-box transcription factor; AltName: Full=Y-box-binding protein 1; Short=YB-1;+++[A0JLU4_HUMAN|Unreviewed]SubName: Full=YBX1 protein {ECO:0000313|EMBL:AAH20164.1}; Flags: Fragment;+++[C9J5V9_HUMAN|Unreviewed]SubName: Full=Nuclease-sensitive element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000405937}; Flags: Fragment;+++[H0Y449_HUMAN|Unreviewed]SubName: Full=Nuclease-sensitive element-binding protein 1 {ECO:0000313|Ensembl:ENSP00000389639}; Flags: Fragment;+++[Q15905_HUMAN|Unreviewed]SubName: Full=YB-1 protein {ECO:0000313|EMBL:CAA65446.1};+++[Q6PKI6_HUMAN|Unreviewed]SubName: Full=YBX1 protein {ECO:0000313|EMBL:AAH00064.1}; Flags: Fragment;"]
[4929,"'NR4A2'",2,11,2,5,"04928///Parathyroid hormone synthesis, secretion and action+++04925///Aldosterone synthesis and secretion","H00057///Parkinson's disease (PD)",null,null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0003707///steroid hormone receptor activity+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0046965///retinoid X receptor binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0008013///beta-catenin binding+++GO:0004879///nuclear receptor activity+++GO:0008270///zinc ion binding+++GO:0035259///glucocorticoid receptor binding","GO:0021952///central nervous system projection neuron axonogenesis+++GO:0008344///adult locomotory behavior+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0001666///response to hypoxia+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0010467///gene expression+++GO:0043085///positive regulation of catalytic activity+++GO:0006351///transcription, DNA-templated+++GO:0042416///dopamine biosynthetic process+++GO:0071542///dopaminergic neuron differentiation+++GO:0042551///neuron maturation+++GO:0001975///response to amphetamine+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045444///fat cell differentiation+++GO:0009791///post-embryonic development+++GO:0034599///cellular response to oxidative stress+++GO:0001764///neuron migration+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:0042417///dopamine metabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0060070///canonical Wnt signaling pathway+++GO:0021953///central nervous system neuron differentiation+++GO:0007165///signal transduction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2001234///negative regulation of apoptotic signaling pathway+++GO:0042053///regulation of dopamine metabolic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0021986///habenula development+++GO:0010468///regulation of gene expression+++GO:0031668///cellular response to extracellular stimulus+++GO:0007399///nervous system development+++GO:0030182///neuron differentiation+++GO:0051866///general adaptation syndrome+++GO:0006355///regulation of transcription, DNA-templated","nuclear receptor subfamily 4 group A member 2","[NR4A2_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 4 group A member 2; AltName: Full=Immediate-early response protein NOT; AltName: Full=Orphan nuclear receptor NURR1; AltName: Full=Transcriptionally-inducible nuclear receptor;+++[A0A0S2Z418_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 isoform 2 {ECO:0000313|EMBL:ALQ33697.1}; Flags: Fragment;+++[C0KWD1_HUMAN|Unreviewed]SubName: Full=Orphan nuclear receptor NR4A2 isoform 1 {ECO:0000313|EMBL:ACN32470.1}; Flags: Fragment;+++[C0KWD2_HUMAN|Unreviewed]SubName: Full=Orphan nuclear receptor NR4A2 isoform 2 {ECO:0000313|EMBL:ACN32471.1}; Flags: Fragment;+++[C9IYM5_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000406808}; Flags: Fragment;+++[C9J8W4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000410952};+++[C9JWQ1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000388120}; Flags: Fragment;+++[E9PBQ4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000415632};+++[F1D8N6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor related 1 {ECO:0000313|EMBL:ADZ17335.1}; SubName: Full=Nuclear receptor subfamily 4 group A member 2 isoform 1 {ECO:0000313|EMBL:ALQ33696.1};+++[F1DAL2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor related 1 {ECO:0000313|EMBL:ADZ17383.1};+++[F8W6I3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000386993};+++[H7BZ00_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4 group A member 2 {ECO:0000313|Ensembl:ENSP00000385379}; Flags: Fragment;+++[Q53EL4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 4, group A, member 2 isoform a variant {ECO:0000313|EMBL:BAD97345.1}; Flags: Fragment;"]
[493869,"'GPX8'",1937,2083,1904,1974.66666666667,"00480///Glutathione metabolism+++04918///Thyroid hormone synthesis+++00590///Arachidonic acid metabolism","H00668///Anemia due to disorders of glutathione metabolism",null,"R07035///Glutathione: 15-HPETE oxidoreductase   2 Glutathione + 15(S)-HPETE <=> Glutathione disulfide + (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + H2O+++R00274///glutathione:hydrogen-peroxide oxidoreductase   Hydrogen peroxide + 2 Glutathione <=> Glutathione disulfide + 2 H2O+++R07034///Glutathione: 5-HPETE oxidoreductase   2 Glutathione + 5(S)-HPETE <=> Glutathione disulfide + 5(S)-HETE + H2O","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005788///endoplasmic reticulum lumen","GO:0016491///oxidoreductase activity+++GO:0004601///peroxidase activity+++GO:0004602///glutathione peroxidase activity","GO:0006979///response to oxidative stress+++GO:0098869///cellular oxidant detoxification+++GO:0034599///cellular response to oxidative stress+++GO:0055114///oxidation-reduction process","glutathione peroxidase 8 (putative)","[GPX8_HUMAN|Reviewed]RecName: Full=Probable glutathione peroxidase 8; Short=GPx-8; Short=GSHPx-8; EC=1.11.1.9;+++[B4DPY0_HUMAN|Unreviewed]RecName: Full=Glutathione peroxidase {ECO:0000256|RuleBase:RU000499};+++[E7ETY7_HUMAN|Unreviewed]RecName: Full=Glutathione peroxidase {ECO:0000256|RuleBase:RU000499};+++[J3KNB5_HUMAN|Unreviewed]SubName: Full=Probable glutathione peroxidase 8 {ECO:0000313|Ensembl:ENSP00000296734};"]
[4975,"'OMP'",0,4,1,1.66666666666667,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0005634///nucleus",null,"GO:0007608///sensory perception of smell+++GO:0050896///response to stimulus+++GO:0022008///neurogenesis+++GO:0007268///chemical synaptic transmission+++GO:0007165///signal transduction","olfactory marker protein","[OMP_HUMAN|Reviewed]RecName: Full=Olfactory marker protein; AltName: Full=Olfactory neuronal-specific protein;"]
[49854,"'ZBTB21'",230,250,157,212.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0008327///methyl-CpG binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 21","[ZBT21_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 21; AltName: Full=Zinc finger protein 295;+++[E7EVF9_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 21 {ECO:0000313|Ensembl:ENSP00000387788}; Flags: Fragment;+++[Q5H9S0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp781N1974 {ECO:0000313|EMBL:CAI45954.1};+++[Q5KS07_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 21 {ECO:0000313|Ensembl:ENSP00000381510}; SubName: Full=Zinc finger protein 295 variant 1 {ECO:0000313|EMBL:BAD86526.1}; SubName: Full=Zinc finger protein 295 variant 3 {ECO:0000313|EMBL:BAD86527.1}; SubName: Full=Zinc finger protein 295 variant 4 {ECO:0000313|EMBL:BAD86528.1}; Flags: Fragment;"]
[4994,"'OR3A1'",4,2,1,2.33333333333333,"04740///Olfactory transduction",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0004984///olfactory receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0050896///response to stimulus+++GO:0007165///signal transduction+++GO:0007608///sensory perception of smell","olfactory receptor family 3 subfamily A member 1","[OR3A1_HUMAN|Reviewed]RecName: Full=Olfactory receptor 3A1; AltName: Full=Olfactory receptor 17-40; Short=OR17-40; AltName: Full=Olfactory receptor OR17-15;+++[A0A087X1K4_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GVP1_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};+++[A0A126GWI0_HUMAN|Unreviewed]SubName: Full=OR3A1 {ECO:0000313|EMBL:ALI87801.1}; SubName: Full=Olfactory receptor, family 3, subfamily A, member 1 {ECO:0000313|EMBL:EAW90518.1};+++[A0A126GWJ3_HUMAN|Unreviewed]RecName: Full=Olfactory receptor {ECO:0000256|RuleBase:RU363047};"]
[5028,"'P2RY1'",31,9,11,17,"04742///Taste transduction+++04611///Platelet activation+++04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0045211///postsynaptic membrane+++GO:0016324///apical plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0014069///postsynaptic density+++GO:0044297///cell body+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0030425///dendrite","GO:0004930///G protein-coupled receptor activity+++GO:0000166///nucleotide binding+++GO:0043531///ADP binding+++GO:0046982///protein heterodimerization activity+++GO:0097110///scaffold protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0031686///A1 adenosine receptor binding+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0045032///ADP-activated adenosine receptor activity+++GO:0038023///signaling receptor activity+++GO:0045031///ATP-activated adenosine receptor activity","GO:0010700///negative regulation of norepinephrine secretion+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0097746///regulation of blood vessel diameter+++GO:0042755///eating behavior+++GO:0071318///cellular response to ATP+++GO:0072659///protein localization to plasma membrane+++GO:0071415///cellular response to purine-containing compound+++GO:0019233///sensory perception of pain+++GO:0008360///regulation of cell shape+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0042060///wound healing+++GO:0060406///positive regulation of penile erection+++GO:0001973///adenosine receptor signaling pathway+++GO:0046887///positive regulation of hormone secretion+++GO:0043270///positive regulation of ion transport+++GO:0007596///blood coagulation+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0008347///glial cell migration+++GO:0007599///hemostasis+++GO:0051100///negative regulation of binding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010469///regulation of signaling receptor activity+++GO:0030168///platelet activation+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0090075///relaxation of muscle+++GO:0007568///aging+++GO:0007165///signal transduction+++GO:0071407///cellular response to organic cyclic compound+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0009612///response to mechanical stimulus+++GO:0070848///response to growth factor","purinergic receptor P2Y1","[P2RY1_HUMAN|Reviewed]RecName: Full=P2Y purinoceptor 1; Short=P2Y1; AltName: Full=ADP receptor {ECO:0000303|PubMed:9038354}; AltName: Full=Purinergic receptor;"]
[503834,"'DPRX'",1,1,0,0.666666666666667,null,"H00481///Cone-rod dystrophy and cone dystrophy+++H00837///Leber congenital amaurosis (LCR)",null,null,"GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","divergent-paired related homeobox","[DPRX_HUMAN|Reviewed]RecName: Full=Divergent paired-related homeobox;"]
[5058,"'PAK1'",916,926,753,865,"04011///MAPK signaling pathway - yeast+++04650///Natural killer cell mediated cytotoxicity+++04360///Axon guidance+++04810///Regulation of actin cytoskeleton+++04666///Fc gamma R-mediated phagocytosis+++04625///C-type lectin receptor signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04392///Hippo signaling pathway - multiple species+++04062///Chemokine signaling pathway+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++04510///Focal adhesion+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0031965///nuclear membrane+++GO:0032587///ruffle membrane+++GO:0001726///ruffle+++GO:0014704///intercalated disc+++GO:0071437///invadopodium+++GO:0005911///cell-cell junction+++GO:0005829///cytosol+++GO:0030424///axon+++GO:0005737///cytoplasm+++GO:0030018///Z disc+++GO:0032991///protein-containing complex+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0048365///Rac GTPase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0005518///collagen binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0042802///identical protein binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043507///positive regulation of JUN kinase activity+++GO:0032147///activation of protein kinase activity+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:2001275///positive regulation of glucose import in response to insulin stimulus+++GO:0046777///protein autophosphorylation+++GO:0032869///cellular response to insulin stimulus+++GO:0042060///wound healing+++GO:0051496///positive regulation of stress fiber assembly+++GO:0045773///positive regulation of axon extension+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0001666///response to hypoxia+++GO:0008284///positive regulation of cell proliferation+++GO:0007266///Rho protein signal transduction+++GO:0001934///positive regulation of protein phosphorylation+++GO:0006887///exocytosis+++GO:0048013///ephrin receptor signaling pathway+++GO:0031295///T cell costimulation+++GO:0030335///positive regulation of cell migration+++GO:0050852///T cell receptor signaling pathway+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0050770///regulation of axonogenesis+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0060244///negative regulation of cell proliferation involved in contact inhibition+++GO:0006915///apoptotic process+++GO:0048812///neuron projection morphogenesis+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0031116///positive regulation of microtubule polymerization+++GO:0042981///regulation of apoptotic process+++GO:0030010///establishment of cell polarity+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0007346///regulation of mitotic cell cycle+++GO:0031532///actin cytoskeleton reorganization+++GO:0006468///protein phosphorylation+++GO:0010763///positive regulation of fibroblast migration+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0021549///cerebellum development","p21 (RAC1) activated kinase 1","[PAK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 1 {ECO:0000303|PubMed:8805275}; EC=2.7.11.1 {ECO:0000269|PubMed:10551809, ECO:0000269|PubMed:22153498, ECO:0000269|PubMed:9032240}; AltName: Full=Alpha-PAK {ECO:0000303|PubMed:9528787}; AltName: Full=p21-activated kinase 1 {ECO:0000303|PubMed:9395435}; Short=PAK-1; AltName: Full=p65-PAK {ECO:0000250|UniProtKB:P35465};+++[A0A024R5P0_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};"]
[5063,"'PAK3'",103.99,127,102.03,111.006666666667,"05211///Renal cell carcinoma+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04660///T cell receptor signaling pathway+++04510///Focal adhesion+++04360///Axon guidance+++04810///Regulation of actin cytoskeleton","H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0014069///postsynaptic density+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005768///endosome+++GO:0005886///plasma membrane","GO:0004674///protein serine/threonine kinase activity+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0017124///SH3 domain binding+++GO:0048365///Rac GTPase binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004708///MAP kinase kinase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0016358///dendrite development+++GO:0071407///cellular response to organic cyclic compound+++GO:0060997///dendritic spine morphogenesis+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0030833///regulation of actin filament polymerization+++GO:0031295///T cell costimulation+++GO:0010763///positive regulation of fibroblast migration+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:0050770///regulation of axonogenesis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0050852///T cell receptor signaling pathway+++GO:0007409///axonogenesis+++GO:0016477///cell migration+++GO:0032197///transposition, RNA-mediated+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0006310///DNA recombination+++GO:0042981///regulation of apoptotic process+++GO:0007266///Rho protein signal transduction+++GO:0048013///ephrin receptor signaling pathway+++GO:0050808///synapse organization+++GO:0007346///regulation of mitotic cell cycle","p21 (RAC1) activated kinase 3","[PAK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 3; EC=2.7.11.1; AltName: Full=Beta-PAK; AltName: Full=Oligophrenin-3; AltName: Full=p21-activated kinase 3; Short=PAK-3;+++[B2RCU6_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};"]
[50807,"'ASAP1'",2612,2740,1949,2433.66666666667,"04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0031253///cell projection membrane+++GO:0016021///integral component of membrane+++GO:0002102///podosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0030246///carbohydrate binding+++GO:0001786///phosphatidylserine binding+++GO:0045296///cadherin binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0046872///metal ion binding","GO:1903527///positive regulation of membrane tubulation+++GO:0061000///negative regulation of dendritic spine development+++GO:0071803///positive regulation of podosome assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0060271///cilium assembly+++GO:0030030///cell projection organization","ArfGAP with SH3 domain, ankyrin repeat and PH domain 1","[ASAP1_HUMAN|Reviewed]RecName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1; AltName: Full=130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein; AltName: Full=ADP-ribosylation factor-directed GTPase-activating protein 1; Short=ARF GTPase-activating protein 1; AltName: Full=Development and differentiation-enhancing factor 1; Short=DEF-1; Short=Differentiation-enhancing factor 1; AltName: Full=PIP2-dependent ARF1 GAP;+++[A0A0A0MRE5_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000350297}; SubName: Full=Development and differentiation enhancing factor 1, isoform CRA_b {ECO:0000313|EMBL:EAW92131.1};+++[E5RFD9_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000428936}; Flags: Fragment;+++[E5RHA9_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000428629};+++[E5RHD7_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000430917}; Flags: Fragment;+++[H0YBF7_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429391}; Flags: Fragment;+++[H0YBM4_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429829}; Flags: Fragment;+++[L8E8W2_HUMAN|Unreviewed]SubName: Full=Alternative protein ASAP1 {ECO:0000313|EMBL:CCQ43599.1};+++[Q8WWA4_HUMAN|Unreviewed]SubName: Full=ASAP1 protein {ECO:0000313|EMBL:AAH20631.1};"]
[50853,"'VILL'",309,161,205,225,{"$nulls":4},"GO:0015629///actin cytoskeleton","GO:0005200///structural constituent of cytoskeleton+++GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0051693///actin filament capping+++GO:0007010///cytoskeleton organization","villin like","[VILL_HUMAN|Reviewed]RecName: Full=Villin-like protein;+++[A0A0S2Z5G7_HUMAN|Unreviewed]SubName: Full=Villin-like isoform 2 {ECO:0000313|EMBL:ALQ34078.1};+++[A0A0S2Z5H2_HUMAN|Unreviewed]SubName: Full=Villin-like isoform 1 {ECO:0000313|EMBL:ALQ34077.1}; Flags: Fragment;+++[C9JUR8_HUMAN|Unreviewed]SubName: Full=Villin-like protein {ECO:0000313|Ensembl:ENSP00000393661}; Flags: Fragment;+++[D6R9H2_HUMAN|Unreviewed]SubName: Full=Villin-like protein {ECO:0000313|Ensembl:ENSP00000422096};+++[E9PFV5_HUMAN|Unreviewed]SubName: Full=Villin-like protein {ECO:0000313|Ensembl:ENSP00000427355}; Flags: Fragment;+++[H7BZ43_HUMAN|Unreviewed]SubName: Full=Villin-like protein {ECO:0000313|Ensembl:ENSP00000387659}; Flags: Fragment;"]
[50940,"'PDE11A'",21,18,11,16.6666666666667,"00230///Purine metabolism+++04934///Cushing's syndrome+++05032///Morphine addiction","H02049///Bilateral macronodular adrenal hyperplasia (BMAH)+++H00260///Pigmented micronodular adrenocortical disease (PPNAD)+++H01431///Cushing's syndrome",null,"R00191///adenosine 3',5'-phosphate 5'-nucleotidohydrolase   3',5'-Cyclic AMP + H2O <=> AMP+++R01234///Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase   3',5'-Cyclic GMP + H2O <=> GMP","GO:0005829///cytosol+++GO:0005575///cellular_component+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0004112///cyclic-nucleotide phosphodiesterase activity+++GO:0030553///cGMP binding+++GO:0046872///metal ion binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0004118///cGMP-stimulated cyclic-nucleotide phosphodiesterase activity+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0003824///catalytic activity","GO:0008152///metabolic process+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0010754///negative regulation of cGMP-mediated signaling","phosphodiesterase 11A","[PDE11_HUMAN|Reviewed]RecName: Full=Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A; EC=3.1.4.35; EC=3.1.4.53; AltName: Full=cAMP and cGMP phosphodiesterase 11A;+++[E9LCZ2_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[E9LCZ3_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[F8WDQ4_HUMAN|Unreviewed]SubName: Full=Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A {ECO:0000313|Ensembl:ENSP00000389777};+++[H0Y6P9_HUMAN|Unreviewed]SubName: Full=Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A {ECO:0000313|Ensembl:ENSP00000406922}; Flags: Fragment;+++[H7C4D0_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067}; Flags: Fragment;+++[Q53S07_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PDE11A {ECO:0000313|EMBL:AAY24130.1}; Flags: Fragment;+++[Q53S13_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PDE11A {ECO:0000313|EMBL:AAX93113.1}; Flags: Fragment;"]
[51002,"'TPRKB'",59,84,93,78.6666666666667,null,"H01722///Galloway-Mowat syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000408///EKC/KEOPS complex+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0005515///protein binding","GO:0002949///tRNA threonylcarbamoyladenosine modification+++GO:0008033///tRNA processing","TP53RK binding protein","[TPRKB_HUMAN|Reviewed]RecName: Full=EKC/KEOPS complex subunit TPRKB {ECO:0000305}; AltName: Full=PRPK-binding protein {ECO:0000303|PubMed:12659830}; AltName: Full=TP53RK-binding protein {ECO:0000303|PubMed:12659830};"]
[51021,"'MRPS16'",646,605,619,623.333333333333,"03010///Ribosome","H00891///Combined oxidative phosphorylation deficiency (COXPD)","M00178///Ribosome, bacteria",null,"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005743///mitochondrial inner membrane+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding","GO:0070126///mitochondrial translational termination+++GO:0032543///mitochondrial translation+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","mitochondrial ribosomal protein S16","[RT16_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S16, mitochondrial; Short=MRP-S16; Short=S16mt; AltName: Full=Mitochondrial small ribosomal subunit protein bS16m {ECO:0000303|PubMed:25838379}; Flags: Precursor;+++[A6ND22_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S16, mitochondrial {ECO:0000313|Ensembl:ENSP00000362031};"]
[51050,"'PI15'",24,16,16,18.6666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0030414///peptidase inhibitor activity","GO:0007275///multicellular organism development+++GO:0010466///negative regulation of peptidase activity+++GO:0008150///biological_process","peptidase inhibitor 15","[PI15_HUMAN|Reviewed]RecName: Full=Peptidase inhibitor 15; Short=PI-15; AltName: Full=25 kDa trypsin inhibitor; Short=p25TI; AltName: Full=Cysteine-rich secretory protein 8; Short=CRISP-8; AltName: Full=SugarCrisp; Flags: Precursor;"]
[51071,"'DERA'",101,89,83,91,"00030///Pentose phosphate pathway",null,null,"R01066///2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)   2-Deoxy-D-ribose 5-phosphate <=> D-Glyceraldehyde 3-phosphate + Acetaldehyde","GO:0034774///secretory granule lumen+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0004139///deoxyribose-phosphate aldolase activity+++GO:0016829///lyase activity+++GO:0003824///catalytic activity","GO:0043312///neutrophil degranulation+++GO:0046386///deoxyribose phosphate catabolic process+++GO:0009264///deoxyribonucleotide catabolic process+++GO:0006098///pentose-phosphate shunt+++GO:0046121///deoxyribonucleoside catabolic process+++GO:0016052///carbohydrate catabolic process","deoxyribose-phosphate aldolase","[DEOC_HUMAN|Reviewed]RecName: Full=Deoxyribose-phosphate aldolase; Short=DERA; EC=4.1.2.4 {ECO:0000269|PubMed:25229427}; AltName: Full=2-deoxy-D-ribose 5-phosphate aldolase; AltName: Full=Phosphodeoxyriboaldolase; Short=Deoxyriboaldolase;+++[E9PJ44_HUMAN|Unreviewed]SubName: Full=Deoxyribose-phosphate aldolase {ECO:0000313|Ensembl:ENSP00000435683};+++[E9PJB9_HUMAN|Unreviewed]SubName: Full=Deoxyribose-phosphate aldolase {ECO:0000313|Ensembl:ENSP00000433801};+++[E9PMH9_HUMAN|Unreviewed]SubName: Full=Deoxyribose-phosphate aldolase {ECO:0000313|Ensembl:ENSP00000434973}; Flags: Fragment;+++[E9PML7_HUMAN|Unreviewed]SubName: Full=Deoxyribose-phosphate aldolase {ECO:0000313|Ensembl:ENSP00000433051}; Flags: Fragment;+++[E9PPK3_HUMAN|Unreviewed]SubName: Full=Deoxyribose-phosphate aldolase {ECO:0000313|Ensembl:ENSP00000432633}; Flags: Fragment;+++[E9PPM8_HUMAN|Unreviewed]SubName: Full=Deoxyribose-phosphate aldolase {ECO:0000313|Ensembl:ENSP00000436999};+++[G3V158_HUMAN|Unreviewed]SubName: Full=2-deoxyribose-5-phosphate aldolase homolog (C. elegans), isoform CRA_a {ECO:0000313|EMBL:EAW96357.1}; SubName: Full=Deoxyribose-phosphate aldolase {ECO:0000313|Ensembl:ENSP00000431757};"]
[51088,"'KLHL5'",1700.98,2114.98,1797,1870.98666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function+++GO:0003779///actin binding","GO:0008150///biological_process+++GO:0043687///post-translational protein modification","kelch like family member 5","[KLHL5_HUMAN|Reviewed]RecName: Full=Kelch-like protein 5;+++[A0A024R9V8_HUMAN|Unreviewed]SubName: Full=Kelch-like 5 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW92909.1};+++[H0Y9Y5_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 5 {ECO:0000313|Ensembl:ENSP00000425512}; Flags: Fragment;+++[H0YAF6_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 5 {ECO:0000313|Ensembl:ENSP00000426949}; Flags: Fragment;+++[L8E8A1_HUMAN|Unreviewed]SubName: Full=Alternative protein KLHL5 {ECO:0000313|EMBL:CCQ43530.1};+++[Q59HD9_HUMAN|Unreviewed]SubName: Full=Kelch-like 5 isoform 2 variant {ECO:0000313|EMBL:BAD92057.1}; Flags: Fragment;+++[Q642I3_HUMAN|Unreviewed]SubName: Full=KLHL5 protein {ECO:0000313|EMBL:AAH81562.1}; Flags: Fragment;+++[Q6PD75_HUMAN|Unreviewed]SubName: Full=KLHL5 protein {ECO:0000313|EMBL:AAH58884.1}; Flags: Fragment;+++[Q7Z6D5_HUMAN|Unreviewed]SubName: Full=KLHL5 protein {ECO:0000313|EMBL:AAH53860.1}; Flags: Fragment;"]
[51105,"'PHF20L1'",690,664,526,626.666666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","PHD finger protein 20 like 1","[P20L1_HUMAN|Reviewed]RecName: Full=PHD finger protein 20-like protein 1;+++[A0A024R9G8_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like 1, isoform CRA_e {ECO:0000313|EMBL:EAW92153.1};+++[A0A0A0MQS0_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000220847};+++[A0A0A8K9A6_HUMAN|Unreviewed]SubName: Full=Up-regulated in lung cancer 1 {ECO:0000313|EMBL:BAQ19747.1};+++[A0A0D9SG14_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000487068};+++[A8MUE8_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000378777};+++[A8MXR8_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000378775};+++[E5RK91_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000428091}; Flags: Fragment;+++[E9PM57_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000433125};+++[F8W9L8_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000378788};+++[H0YC05_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000430688}; Flags: Fragment;+++[H0YDF7_HUMAN|Unreviewed]SubName: Full=PHD finger protein 20-like protein 1 {ECO:0000313|Ensembl:ENSP00000433524}; Flags: Fragment;+++[Q9H8G4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ13649 fis, clone PLACE1011399, weakly similar to Homo sapiens CGI-72 protein mRNA {ECO:0000313|EMBL:BAB14653.1};"]
[51121,"'RPL26L1'",222,285,289,265.333333333333,"03010///Ribosome","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0005840///ribosome+++GO:0070062///extracellular exosome+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0042273///ribosomal large subunit biogenesis+++GO:0002181///cytoplasmic translation+++GO:0006412///translation","ribosomal protein L26 like 1","[RL26L_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L26-like 1; AltName: Full=Large ribosomal subunit protein uL24-like 1;+++[E5RHH1_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L26-like 1 {ECO:0000313|Ensembl:ENSP00000429783}; Flags: Fragment;+++[E5RIT6_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L26-like 1 {ECO:0000313|Ensembl:ENSP00000430673}; Flags: Fragment;"]
[51142,"'CHCHD2'",1602,1620,1955,1725.66666666667,{"$nulls":4},"GO:0005758///mitochondrial intermembrane space+++GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding","GO:1900037///regulation of cellular response to hypoxia+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization","coiled-coil-helix-coiled-coil-helix domain containing 2","[CHCH2_HUMAN|Reviewed]RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 2; AltName: Full=Aging-associated gene 10 protein; AltName: Full=HCV NS2 trans-regulated protein; Short=NS2TP;"]
[51161,"'C3orf18'",216,229,235,226.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"chromosome 3 open reading frame 18","[CC018_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C3orf18; AltName: Full=Protein G20;+++[B2R7V1_HUMAN|Unreviewed]SubName: Full=Chromosome 3 open reading frame 18, isoform CRA_a {ECO:0000313|EMBL:EAW65122.1}; SubName: Full=cDNA FLJ42447 fis, clone BRACE1000186, highly similar to Homo sapiens g20 protein {ECO:0000313|EMBL:BAG54038.1}; SubName: Full=cDNA, FLJ93615, Homo sapiens g20 protein (LOC51161), mRNA {ECO:0000313|EMBL:BAG35948.1};+++[C9IYC4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C3orf18 {ECO:0000313|Ensembl:ENSP00000399129};+++[F8WCC4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C3orf18 {ECO:0000313|Ensembl:ENSP00000400599};+++[Q6ZP18_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26717 fis, clone PNC03228 {ECO:0000313|EMBL:BAC85307.1};"]
[51164,"'DCTN4'",994,1023,830,949,"05016///Huntington's disease+++04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005938///cell cortex+++GO:0000776///kinetochore+++GO:0005869///dynactin complex+++GO:0030017///sarcomere+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0047485///protein N-terminus binding","GO:0007097///nuclear migration+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","dynactin subunit 4","[DCTN4_HUMAN|Reviewed]RecName: Full=Dynactin subunit 4; Short=Dyn4; AltName: Full=Dynactin subunit p62;+++[A0A0S2Z5B8_HUMAN|Unreviewed]SubName: Full=Dynactin 4 isoform 2 {ECO:0000313|EMBL:ALQ34096.1}; Flags: Fragment;+++[A0A0S2Z5D4_HUMAN|Unreviewed]SubName: Full=Dynactin 4 isoform 1 {ECO:0000313|EMBL:ALQ34095.1}; Flags: Fragment;+++[A0A0S2Z5D5_HUMAN|Unreviewed]SubName: Full=Dynactin 4 isoform 3 {ECO:0000313|EMBL:ALQ34097.1};+++[E5RGG1_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 4 {ECO:0000313|Ensembl:ENSP00000430183}; Flags: Fragment;+++[E5RI97_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 4 {ECO:0000313|Ensembl:ENSP00000429489};+++[E5RK21_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 4 {ECO:0000313|Ensembl:ENSP00000428987}; Flags: Fragment;+++[H9KVE0_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 4 {ECO:0000313|Ensembl:ENSP00000430993}; Flags: Fragment;+++[Q9NSJ5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp761J032 {ECO:0000313|EMBL:CAB82417.1}; Flags: Fragment;"]
[51201,"'ZDHHC2'",518,448,412,459.333333333333,null,"H00658///Syndromic X-linked mental retardation",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0055038///recycling endosome membrane","GO:0016740///transferase activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016409///palmitoyltransferase activity","GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0044267///cellular protein metabolic process+++GO:0018345///protein palmitoylation+++GO:0006612///protein targeting to membrane","zinc finger DHHC-type containing 2","[ZDHC2_HUMAN|Reviewed]RecName: Full=Palmitoyltransferase ZDHHC2; EC=2.3.1.225; AltName: Full=Reduced expression associated with metastasis protein; Short=Ream; AltName: Full=Reduced expression in cancer protein; Short=Rec; AltName: Full=Zinc finger DHHC domain-containing protein 2; Short=DHHC-2; AltName: Full=Zinc finger protein 372;+++[A0A140VKD9_HUMAN|Unreviewed]RecName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119}; EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119};+++[A0A1Y8EM58_HUMAN|Unreviewed]SubName: Full=Palmitoyltransferase ZDHHC2 {ECO:0000313|Ensembl:ENSP00000430804}; Flags: Fragment;+++[E5RFZ7_HUMAN|Unreviewed]RecName: Full=Palmitoyltransferase {ECO:0000256|RuleBase:RU079119}; EC=2.3.1.225 {ECO:0000256|RuleBase:RU079119}; Flags: Fragment;"]
[51206,"'GP6'",5,2,7,4.66666666666667,"04512///ECM-receptor interaction+++04611///Platelet activation","H01235///Bleeding disorder platelet-type",null,null,"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0097197///tetraspanin-enriched microdomain","GO:0038023///signaling receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005518///collagen binding+++GO:0005515///protein binding","GO:0030168///platelet activation+++GO:0050900///leukocyte migration+++GO:0007596///blood coagulation+++GO:0007167///enzyme linked receptor protein signaling pathway+++GO:0007599///hemostasis","glycoprotein VI platelet","[GPVI_HUMAN|Reviewed]RecName: Full=Platelet glycoprotein VI {ECO:0000305}; Short=GPVI {ECO:0000305}; AltName: Full=Glycoprotein 6; Flags: Precursor;+++[K7EIW7_HUMAN|Unreviewed]SubName: Full=Platelet glycoprotein VI {ECO:0000313|Ensembl:ENSP00000464922}; Flags: Fragment;+++[Q9HCN5_HUMAN|Unreviewed]SubName: Full=Glycoprotein VI {ECO:0000313|EMBL:AAN86273.1}; SubName: Full=Platelet glycoprotein VI {ECO:0000313|EMBL:BAB12248.1}; Flags: Fragment;"]
[51252,"'FAM178B'",183,59,128,123.333333333333,"04137///Mitophagy - animal+++04360///Axon guidance+++04140///Autophagy - animal","H00527///Retinitis pigmentosa (RP)+++H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0005615///extracellular space+++GO:0045211///postsynaptic membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0030672///synaptic vesicle membrane+++GO:0014069///postsynaptic density+++GO:0016021///integral component of membrane",null,"GO:0001843///neural tube closure+++GO:0021535///cell migration in hindbrain+++GO:0021549///cerebellum development+++GO:0042692///muscle cell differentiation+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway","family with sequence similarity 178 member B","[F178B_HUMAN|Reviewed]RecName: Full=Protein FAM178B;+++[B3KV66_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16181 fis, clone BRSTN2002400 {ECO:0000313|EMBL:BAG53678.1};"]
[51259,"'TMEM216'",98,78,103,93,null,"H00261///Meckel syndrome (MKS)+++H00530///Joubert syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0036038///MKS complex+++GO:0005829///cytosol+++GO:0035869///ciliary transition zone","GO:0005515///protein binding","GO:0030030///cell projection organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:1905515///non-motile cilium assembly+++GO:0060271///cilium assembly","transmembrane protein 216","[TM216_HUMAN|Reviewed]RecName: Full=Transmembrane protein 216;+++[J3QT25_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 216 {ECO:0000313|EMBL:ALX00016.1, ECO:0000313|Ensembl:ENSP00000381950};"]
[51276,"'ZNF571'",11,13,9,11,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 571","[ZN571_HUMAN|Reviewed]RecName: Full=Zinc finger protein 571;+++[A0A024R0L0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 571, isoform CRA_a {ECO:0000313|EMBL:EAW56738.1};+++[A8K5U8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75230, highly similar to Homo sapiens HSPC059 protein (HSPC059), mRNA {ECO:0000313|EMBL:BAF84102.1};+++[K7ELU5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 571 {ECO:0000313|Ensembl:ENSP00000466225}; Flags: Fragment;+++[K7ERB9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 571 {ECO:0000313|Ensembl:ENSP00000468192};+++[Q24JS6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 571 {ECO:0000313|EMBL:AAI14480.1};"]
[513,"'ATP5F1D'",1694,1854,2222,1923.33333333333,"05016///Huntington's disease+++04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways+++05010///Alzheimer's disease+++05012///Parkinson's disease",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005759///mitochondrial matrix+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005743///mitochondrial inner membrane+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0005215///transporter activity+++GO:0016887///ATPase activity+++GO:0043531///ADP binding+++GO:0005524///ATP binding+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0022857///transmembrane transporter activity","GO:0006754///ATP biosynthetic process+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0006119///oxidative phosphorylation+++GO:0006811///ion transport+++GO:0042407///cristae formation+++GO:0015986///ATP synthesis coupled proton transport+++GO:0046688///response to copper ion+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport","ATP synthase F1 subunit delta","[ATPD_HUMAN|Reviewed]RecName: Full=ATP synthase subunit delta, mitochondrial {ECO:0000305}; AltName: Full=ATP synthase F1 subunit delta {ECO:0000312|HGNC:HGNC:837}; AltName: Full=F-ATPase delta subunit; Flags: Precursor;+++[A0A087WTL3_HUMAN|Unreviewed]SubName: Full=ATP synthase subunit delta, mitochondrial {ECO:0000313|Ensembl:ENSP00000477964}; Flags: Fragment;"]
[51308,"'REEP2'",891,1114,1130,1045,null,"H00266///Hereditary spastic paraplegia (SPG)+++H00856///Distal hereditary motor neuropathies (dHMN)",null,null,"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005881///cytoplasmic microtubule+++GO:0005789///endoplasmic reticulum membrane","GO:0031883///taste receptor binding","GO:0050916///sensory perception of sweet taste+++GO:0032386///regulation of intracellular transport+++GO:0050913///sensory perception of bitter taste+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0032596///protein transport into membrane raft","receptor accessory protein 2","[REEP2_HUMAN|Reviewed]RecName: Full=Receptor expression-enhancing protein 2;+++[A0A087WV88_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006};+++[A8K3D2_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006};+++[B4DE60_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006};+++[D3DQC0_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006};+++[D6RB42_HUMAN|Unreviewed]SubName: Full=Receptor expression-enhancing protein 2 {ECO:0000313|Ensembl:ENSP00000424441};+++[H0YAC5_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006}; Flags: Fragment;"]
[51338,"'MS4A4A'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"membrane spanning 4-domains A4A","[M4A4A_HUMAN|Reviewed]RecName: Full=Membrane-spanning 4-domains subfamily A member 4A; AltName: Full=CD20 antigen-like 1; AltName: Full=Four-span transmembrane protein 1;+++[F8W866_HUMAN|Unreviewed]SubName: Full=Membrane-spanning 4-domains subfamily A member 4A {ECO:0000313|Ensembl:ENSP00000340356};+++[H0YE49_HUMAN|Unreviewed]SubName: Full=Membrane-spanning 4-domains subfamily A member 4A {ECO:0000313|Ensembl:ENSP00000434983}; Flags: Fragment;+++[Q4JF27_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90600 fis, clone PLACE1001401, highly similar to Membrane-spanning 4-domains subfamily A member 4A {ECO:0000313|EMBL:BAC11389.1};"]
[5136,"'PDE1A'",2,4,6,4,"04740///Olfactory transduction+++05032///Morphine addiction+++04742///Taste transduction+++04020///Calcium signaling pathway+++00230///Purine metabolism+++04924///Renin secretion",null,null,"R00191///adenosine 3',5'-phosphate 5'-nucleotidohydrolase   3',5'-Cyclic AMP + H2O <=> AMP+++R01234///Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase   3',5'-Cyclic GMP + H2O <=> GMP","GO:0043025///neuronal cell body+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0005516///calmodulin binding+++GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity+++GO:0004115///3',5'-cyclic-AMP phosphodiesterase activity+++GO:0048101///calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0004117///calmodulin-dependent cyclic-nucleotide phosphodiesterase activity","GO:0048660///regulation of smooth muscle cell proliferation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0046069///cGMP catabolic process+++GO:0034391///regulation of smooth muscle cell apoptotic process","phosphodiesterase 1A","[PDE1A_HUMAN|Reviewed]RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Short=Cam-PDE 1A; EC=3.1.4.17; AltName: Full=61 kDa Cam-PDE; AltName: Full=hCam-1;+++[B7Z226_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[B7Z7A2_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[Q53T15_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PDE1A {ECO:0000313|EMBL:AAY14812.1}; Flags: Fragment;+++[Q53TB0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PDE1A {ECO:0000313|EMBL:AAY14837.1}; Flags: Fragment;+++[Q9H3Q8_HUMAN|Unreviewed]SubName: Full=Calmodulin-dependent phosphodiesterase {ECO:0000313|EMBL:BAB20038.1}; Flags: Fragment;+++[Q9H3Q9_HUMAN|Unreviewed]SubName: Full=Calmodulin-dependent phosphodiesterase {ECO:0000313|EMBL:BAB20037.1}; Flags: Fragment;+++[Q9UNL9_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase {ECO:0000313|EMBL:AAD40741.1}; Flags: Fragment;+++[Q9Y246_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase {ECO:0000313|EMBL:AAD40739.1}; Flags: Fragment;+++[Q9Y633_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase {ECO:0000313|EMBL:AAD40740.1}; Flags: Fragment;+++[Q9Y634_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase {ECO:0000313|EMBL:AAD40737.1}; Flags: Fragment;"]
[51389,"'RWDD1'",986,952,898,945.333333333333,null,"H00564///Primary ciliary dyskinesia",null,null,"GO:0005737///cytoplasm+++GO:0005844///polysome","GO:0005515///protein binding","GO:2000825///positive regulation of androgen receptor activity+++GO:0030521///androgen receptor signaling pathway+++GO:0007569///cell aging+++GO:0002181///cytoplasmic translation+++GO:0034599///cellular response to oxidative stress+++GO:0071394///cellular response to testosterone stimulus","RWD domain containing 1","[RWDD1_HUMAN|Reviewed]RecName: Full=RWD domain-containing protein 1; AltName: Full=DRG family-regulatory protein 2;+++[E5RGQ3_HUMAN|Unreviewed]SubName: Full=RWD domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429942}; Flags: Fragment;+++[E5RGS5_HUMAN|Unreviewed]SubName: Full=RWD domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000428704}; Flags: Fragment;+++[E5RJE3_HUMAN|Unreviewed]SubName: Full=RWD domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000429070}; Flags: Fragment;"]
[514,"'ATP5F1E'",1462,1659,1712,1611,"00190///Oxidative phosphorylation+++01100///Metabolic pathways+++05016///Huntington's disease+++05010///Alzheimer's disease+++04714///Thermogenesis+++05012///Parkinson's disease","H01369///ATP synthase deficiency","M00158///F-type ATPase, eukaryotes",null,"GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0000275///mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005739///mitochondrion+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0045261///proton-transporting ATP synthase complex, catalytic core F(1)+++GO:0005759///mitochondrial matrix","GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0016787///hydrolase activity","GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0006811///ion transport+++GO:0006754///ATP biosynthetic process+++GO:0015986///ATP synthesis coupled proton transport","ATP synthase F1 subunit epsilon","[ATP5E_HUMAN|Reviewed]RecName: Full=ATP synthase subunit epsilon, mitochondrial {ECO:0000305}; Short=ATPase subunit epsilon; AltName: Full=ATP synthase F1 subunit epsilon {ECO:0000312|HGNC:HGNC:838};"]
[5145,"'PDE6A'",17.73,14.17,22.98,18.2933333333333,"00230///Purine metabolism+++04744///Phototransduction","H00527///Retinitis pigmentosa (RP)",null,"R01234///Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase   3',5'-Cyclic GMP + H2O <=> GMP","GO:0097381///photoreceptor disc membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0047555///3',5'-cyclic-GMP phosphodiesterase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0004114///3',5'-cyclic-nucleotide phosphodiesterase activity","GO:0007165///signal transduction+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0050896///response to stimulus+++GO:0060041///retina development in camera-type eye+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0007601///visual perception+++GO:0007186///G protein-coupled receptor signaling pathway","phosphodiesterase 6A","[PDE6A_HUMAN|Reviewed]RecName: Full=Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha; Short=GMP-PDE alpha; EC=3.1.4.35; AltName: Full=PDE V-B1; Flags: Precursor;+++[F1T0K3_HUMAN|Unreviewed]RecName: Full=Phosphodiesterase {ECO:0000256|RuleBase:RU363067}; EC=3.1.4.- {ECO:0000256|RuleBase:RU363067};+++[O75316_HUMAN|Unreviewed]SubName: Full=Rod photoreceptor cGMP phosphodiesterase alpha subunit {ECO:0000313|EMBL:AAC33831.1}; Flags: Fragment;"]
[51463,"'GPR89B'",49.44,92.42,56.2,66.02,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0030660///Golgi-associated vesicle membrane+++GO:0032580///Golgi cisterna membrane","GO:0008308///voltage-gated anion channel activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0034765///regulation of ion transmembrane transport+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0051452///intracellular pH reduction+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0015031///protein transport","G protein-coupled receptor 89B","[GPHRA_HUMAN|Reviewed]RecName: Full=Golgi pH regulator A; AltName: Full=Protein GPR89A; AltName: Full=Putative MAPK-activating protein PM01; AltName: Full=Putative NF-kappa-B-activating protein 90;+++[GPHRB_HUMAN|Reviewed]RecName: Full=Golgi pH regulator B; AltName: Full=Protein GPR89B;+++[X5D7G6_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 89A isoform C {ECO:0000313|EMBL:AHW56487.1}; SubName: Full=G protein-coupled receptor 89B isoform C {ECO:0000313|EMBL:AHW56490.1}; Flags: Fragment;"]
[51513,"'ETV7'",32,19,51,34,"05202///Transcriptional misregulation in cancer+++04013///MAPK signaling pathway - fly+++04320///Dorso-ventral axis formation","H00978///Thrombocytopenia (THC)",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0030154///cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009887///animal organ morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II","ETS variant 7","[ETV7_HUMAN|Reviewed]RecName: Full=Transcription factor ETV7; AltName: Full=ETS translocation variant 7; AltName: Full=ETS-related protein Tel2; AltName: Full=Tel-related Ets factor; AltName: Full=Transcription factor Tel-2;"]
[51522,"'TMEM14C'",1129,1164,1109,1134,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0006839///mitochondrial transport+++GO:0070453///regulation of heme biosynthetic process+++GO:0006783///heme biosynthetic process+++GO:0030218///erythrocyte differentiation","transmembrane protein 14C","[TM14C_HUMAN|Reviewed]RecName: Full=Transmembrane protein 14C;+++[A0A024QZV6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 14C, isoform CRA_b {ECO:0000313|EMBL:EAW55275.1}; Flags: Fragment;+++[A0A024R001_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 14C, isoform CRA_a {ECO:0000313|EMBL:EAW55273.1};"]
[51535,"'PPHLN1'",486,504,567,519,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0031424///keratinization+++GO:0045892///negative regulation of transcription, DNA-templated","periphilin 1","[PPHLN_HUMAN|Reviewed]RecName: Full=Periphilin-1 {ECO:0000303|PubMed:12853457}; AltName: Full=CDC7 expression repressor {ECO:0000303|PubMed:15474462}; Short=CR {ECO:0000303|PubMed:15474462}; AltName: Full=Gastric cancer antigen Ga50 {ECO:0000303|PubMed:12087473};+++[B7Z8L1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52823, highly similar to Periphilin-1 {ECO:0000313|EMBL:BAH13997.1};+++[F8VP48_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000450346};+++[F8VPY7_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000450274}; Flags: Fragment;+++[F8VRK2_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000448645};+++[F8VWU8_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000449772}; Flags: Fragment;+++[F8VXV7_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000449031}; Flags: Fragment;+++[F8W0Q9_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000447168};+++[F8W6A0_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000256678};+++[F8WF16_HUMAN|Unreviewed]SubName: Full=Periphilin-1 {ECO:0000313|Ensembl:ENSP00000322048};"]
[51560,"'RAB6B'",1050,902,876,942.666666666667,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0000139///Golgi membrane+++GO:0098793///presynapse+++GO:0005829///cytosol+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0003924///GTPase activity+++GO:0031489///myosin V binding+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0015031///protein transport+++GO:0032482///Rab protein signal transduction+++GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0042147///retrograde transport, endosome to Golgi","RAB6B, member RAS oncogene family","[RAB6B_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-6B;+++[C9J0I2_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000418540};+++[C9JB90_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000417433}; Flags: Fragment;+++[C9JU14_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000419526}; Flags: Fragment;+++[J3KR73_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-6B {ECO:0000313|Ensembl:ENSP00000419941}; Flags: Fragment;+++[Q6AZ91_HUMAN|Unreviewed]SubName: Full=RAB6B protein {ECO:0000313|EMBL:AAH78662.1};+++[Q9UL29_HUMAN|Unreviewed]SubName: Full=GTP-binding protein RAB6B {ECO:0000313|EMBL:AAF00044.1}; Flags: Fragment;"]
[51593,"'SRRT'",1731,1738,1774,1747.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:0031053///primary miRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0097150///neuronal stem cell population maintenance+++GO:0031047///gene silencing by RNA+++GO:0050769///positive regulation of neurogenesis+++GO:0046685///response to arsenic-containing substance+++GO:0006397///mRNA processing+++GO:0006355///regulation of transcription, DNA-templated","serrate, RNA effector molecule","[SRRT_HUMAN|Reviewed]RecName: Full=Serrate RNA effector molecule homolog; AltName: Full=Arsenite-resistance protein 2;+++[A0A087X0F4_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000483348};+++[A0A0A0MSP6_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000398618}; Flags: Fragment;+++[A0A286YEP7_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000492916}; Flags: Fragment;+++[C9JUL9_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000400912}; Flags: Fragment;+++[H7C0U8_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000396807}; Flags: Fragment;+++[H7C1K0_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000400703}; Flags: Fragment;+++[H7C3A1_HUMAN|Unreviewed]SubName: Full=Serrate RNA effector molecule homolog {ECO:0000313|Ensembl:ENSP00000410588}; Flags: Fragment;"]
[51614,"'ERGIC3'",6071,6404,6949,6474.66666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0030173///integral component of Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0005783///endoplasmic reticulum+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane",null,"GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER","ERGIC and golgi 3","[ERGI3_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3; AltName: Full=Serologically defined breast cancer antigen NY-BR-84;+++[A0A0C4DH46_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3 {ECO:0000313|Ensembl:ENSP00000389398};+++[A0A1W2PPS8_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3 {ECO:0000313|Ensembl:ENSP00000491710};+++[A2TJK5_HUMAN|Unreviewed]SubName: Full=ERGIC and golgi 3, isoform CRA_a {ECO:0000313|EMBL:EAW76199.1}; SubName: Full=Endoplasmic reticulum-localized protein ERp43 {ECO:0000313|EMBL:ABM92879.1};+++[A6PVJ2_HUMAN|Unreviewed]SubName: Full=ERGIC and golgi 3 {ECO:0000313|EMBL:CAO03348.2}; SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3 {ECO:0000313|Ensembl:ENSP00000414490}; Flags: Fragment;+++[A6PVJ3_HUMAN|Unreviewed]SubName: Full=ERGIC and golgi 3 {ECO:0000313|EMBL:CAO03349.1}; Flags: Fragment;+++[H0Y5K5_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3 {ECO:0000313|Ensembl:ENSP00000399124}; Flags: Fragment;+++[H0Y621_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3 {ECO:0000313|Ensembl:ENSP00000402480}; Flags: Fragment;+++[H0Y6Z0_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3 {ECO:0000313|Ensembl:ENSP00000408840}; Flags: Fragment;+++[H0Y802_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 3 {ECO:0000313|Ensembl:ENSP00000416402}; Flags: Fragment;+++[Q5JWS0_HUMAN|Unreviewed]SubName: Full=ERGIC and golgi 3 {ECO:0000313|EMBL:CAI42843.1}; Flags: Fragment;+++[Q5JWS1_HUMAN|Unreviewed]SubName: Full=ERGIC and golgi 3 {ECO:0000313|EMBL:CAI42845.1}; Flags: Fragment;+++[Q5JWS2_HUMAN|Unreviewed]SubName: Full=ERGIC and golgi 3 {ECO:0000313|EMBL:CAI42844.1}; Flags: Fragment;"]
[51643,"'TMBIM4'",459,389,448.32,432.106666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005795///Golgi stack+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0050848///regulation of calcium-mediated signaling+++GO:0006915///apoptotic process","transmembrane BAX inhibitor motif containing 4","[LFG4_HUMAN|Reviewed]RecName: Full=Protein lifeguard 4; AltName: Full=Golgi anti-apoptotic protein; AltName: Full=Protein S1R; AltName: Full=Transmembrane BAX inhibitor motif-containing protein 4; AltName: Full=Z-protein;+++[A0A087WXH1_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000481025};+++[E7EWY5_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000381114};+++[F5GXT9_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000440964};+++[F5H1S4_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000438957};+++[G3V1M2_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000441291};+++[G3V1R8_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000444639}; SubName: Full=Transmembrane BAX inhibitor motif containing 4, isoform CRA_c {ECO:0000313|EMBL:EAW97160.1};+++[G3XAA5_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000286424}; SubName: Full=Transmembrane BAX inhibitor motif containing 4, isoform CRA_a {ECO:0000313|EMBL:EAW97158.1};+++[L7MUG5_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000451688};+++[Q7Z782_HUMAN|Unreviewed]SubName: Full=Protein lifeguard 4 {ECO:0000313|Ensembl:ENSP00000488909}; SubName: Full=TMBIM4 protein {ECO:0000313|EMBL:AAH04401.1};+++[Q9HC19_HUMAN|Unreviewed]SubName: Full=MDS013 {ECO:0000313|EMBL:AAG14950.1};"]
[51663,"'ZFR'",1941,1986,1438,1788.33333333333,{"$nulls":4},"GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0003676///nucleic acid binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding","GO:0007275///multicellular organism development","zinc finger RNA binding protein","[ZFR_HUMAN|Reviewed]RecName: Full=Zinc finger RNA-binding protein; Short=hZFR; AltName: Full=M-phase phosphoprotein homolog;+++[B2RNR6_HUMAN|Unreviewed]SubName: Full=Zinc finger RNA binding protein {ECO:0000313|EMBL:AAI37086.1};+++[H0Y8W1_HUMAN|Unreviewed]SubName: Full=Zinc finger RNA-binding protein {ECO:0000313|Ensembl:ENSP00000422300}; Flags: Fragment;+++[L0R5H8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZFR {ECO:0000313|EMBL:CCO13854.1};+++[Q05D65_HUMAN|Unreviewed]SubName: Full=ZFR protein {ECO:0000313|EMBL:AAH17879.1};"]
[51692,"'CPSF3'",458,532,494,494.666666666667,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex","GO:0004521///endoribonuclease activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0004518///nuclease activity+++GO:0008409///5'-3' exonuclease activity+++GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity","GO:0006369///termination of RNA polymerase II transcription+++GO:0006406///mRNA export from nucleus+++GO:0098789///pre-mRNA cleavage required for polyadenylation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:0031126///snoRNA 3'-end processing+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0034247///snoRNA splicing+++GO:0006379///mRNA cleavage+++GO:0006378///mRNA polyadenylation+++GO:0000398///mRNA splicing, via spliceosome","cleavage and polyadenylation specific factor 3","[CPSF3_HUMAN|Reviewed]RecName: Full=Cleavage and polyadenylation specificity factor subunit 3; EC=3.1.27.- {ECO:0000269|PubMed:15037765, ECO:0000269|PubMed:17128255}; AltName: Full=Cleavage and polyadenylation specificity factor 73 kDa subunit; Short=CPSF 73 kDa subunit; AltName: Full=mRNA 3'-end-processing endonuclease CPSF-73;+++[C9JZH6_HUMAN|Unreviewed]SubName: Full=Cleavage and polyadenylation-specificity factor subunit 3 {ECO:0000313|Ensembl:ENSP00000419744}; Flags: Fragment;+++[G5E9W3_HUMAN|Unreviewed]SubName: Full=Cleavage and polyadenylation specific factor 3, 73kDa, isoform CRA_b {ECO:0000313|EMBL:EAX00990.1}; SubName: Full=Cleavage and polyadenylation-specificity factor subunit 3 {ECO:0000313|Ensembl:ENSP00000418957};+++[Q05BZ5_HUMAN|Unreviewed]SubName: Full=CPSF3 protein {ECO:0000313|EMBL:AAH30988.1}; Flags: Fragment;"]
[5172,"'SLC26A4'",2,1.78,2.48,2.08666666666667,"04918///Thyroid hormone synthesis","H00251///Thyroid dyshormonogenesis+++H00605///Deafness, autosomal recessive",null,null,"GO:0031526///brush border membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016324///apical plasma membrane","GO:0008271///secondary active sulfate transmembrane transporter activity+++GO:0015106///bicarbonate transmembrane transporter activity+++GO:0015116///sulfate transmembrane transporter activity+++GO:0015108///chloride transmembrane transporter activity+++GO:0015301///anion:anion antiporter activity+++GO:0019531///oxalate transmembrane transporter activity+++GO:0015111///iodide transmembrane transporter activity","GO:0006885///regulation of pH+++GO:0007605///sensory perception of sound+++GO:0098656///anion transmembrane transport+++GO:0015705///iodide transport+++GO:0042391///regulation of membrane potential+++GO:1902476///chloride transmembrane transport+++GO:0055085///transmembrane transport+++GO:0032880///regulation of protein localization+++GO:0015698///inorganic anion transport+++GO:0015701///bicarbonate transport+++GO:0006811///ion transport+++GO:1902358///sulfate transmembrane transport+++GO:0019532///oxalate transport+++GO:0008272///sulfate transport","solute carrier family 26 member 4","[S26A4_HUMAN|Reviewed]RecName: Full=Pendrin; AltName: Full=Sodium-independent chloride/iodide transporter; AltName: Full=Solute carrier family 26 member 4;+++[A0A2R8Y4W7_HUMAN|Unreviewed]SubName: Full=Pendrin {ECO:0000313|Ensembl:ENSP00000494344}; Flags: Fragment;+++[C9JQG1_HUMAN|Unreviewed]SubName: Full=Pendrin {ECO:0000313|Ensembl:ENSP00000394760}; Flags: Fragment;+++[Q75MC7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC26A4 {ECO:0000313|EMBL:AAS02011.1}; Flags: Fragment;"]
[5175,"'PECAM1'",3,4,6,4.33333333333333,"04514///Cell adhesion molecules (CAMs)+++05418///Fluid shear stress and atherosclerosis+++04670///Leukocyte transendothelial migration+++05144///Malaria",{"$nulls":3},"GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030485///smooth muscle contractile fiber+++GO:0071944///cell periphery+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0009897///external side of plasma membrane+++GO:0044291///cell-cell contact zone+++GO:0030667///secretory granule membrane+++GO:0016020///membrane+++GO:0031092///platelet alpha granule membrane+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0050904///diapedesis+++GO:0043542///endothelial cell migration+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0050900///leukocyte migration+++GO:0006909///phagocytosis+++GO:0072011///glomerular endothelium development+++GO:0007155///cell adhesion+++GO:0072672///neutrophil extravasation+++GO:0001525///angiogenesis+++GO:0007165///signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0008037///cell recognition+++GO:0090673///endothelial cell-matrix adhesion+++GO:0043312///neutrophil degranulation+++GO:0002576///platelet degranulation+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0042060///wound healing+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0030334///regulation of cell migration+++GO:0030198///extracellular matrix organization+++GO:0001886///endothelial cell morphogenesis","platelet and endothelial cell adhesion molecule 1","[PECA1_HUMAN|Reviewed]RecName: Full=Platelet endothelial cell adhesion molecule; Short=PECAM-1; AltName: Full=EndoCAM; AltName: Full=GPIIA'; AltName: Full=PECA1; AltName: CD_antigen=CD31; Flags: Precursor;+++[A0A075B727_HUMAN|Unreviewed]SubName: Full=Platelet endothelial cell adhesion molecule {ECO:0000313|Ensembl:ENSP00000455663}; Flags: Fragment;+++[A0A075B728_HUMAN|Unreviewed]SubName: Full=Platelet endothelial cell adhesion molecule {ECO:0000313|Ensembl:ENSP00000455931}; Flags: Fragment;+++[A0A075B737_HUMAN|Unreviewed]SubName: Full=Platelet endothelial cell adhesion molecule {ECO:0000313|Ensembl:ENSP00000457218}; Flags: Fragment;"]
[51780,"'KDM3B'",1542,1290,1027,1286.33333333333,"04714///Thermogenesis",{"$nulls":3},"GO:0005634///nucleus+++GO:0000785///chromatin+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0016209///antioxidant activity+++GO:0051213///dioxygenase activity+++GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0031490///chromatin DNA binding","GO:0055114///oxidation-reduction process+++GO:0098869///cellular oxidant detoxification+++GO:0033169///histone H3-K9 demethylation+++GO:0006325///chromatin organization+++GO:0072718///response to cisplatin","lysine demethylase 3B","[KDM3B_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 3B; EC=1.14.11.-; AltName: Full=JmjC domain-containing histone demethylation protein 2B; AltName: Full=Jumonji domain-containing protein 1B; AltName: Full=Nuclear protein 5qNCA;+++[A4FUT8_HUMAN|Unreviewed]SubName: Full=JMJD1B protein {ECO:0000313|EMBL:AAI17694.1}; Flags: Fragment;+++[H0Y946_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 3B {ECO:0000313|Ensembl:ENSP00000423012}; Flags: Fragment;+++[H0Y9V5_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 3B {ECO:0000313|Ensembl:ENSP00000425186}; Flags: Fragment;"]
[5191,"'PEX7'",59,39,64,54,"04146///Peroxisome","H00207///Rhizomelic chondrodysplasia punctata+++H00075///Refsum disease+++H00205///Peroxisome biogenesis disorder",null,null,"GO:0005778///peroxisomal membrane+++GO:0005782///peroxisomal matrix+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005053///peroxisome matrix targeting signal-2 binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0019899///enzyme binding","GO:0008611///ether lipid biosynthetic process+++GO:0001764///neuron migration+++GO:0007031///peroxisome organization+++GO:0006635///fatty acid beta-oxidation+++GO:0006625///protein targeting to peroxisome+++GO:0016558///protein import into peroxisome matrix+++GO:0001958///endochondral ossification+++GO:0015031///protein transport","peroxisomal biogenesis factor 7","[PEX7_HUMAN|Reviewed]RecName: Full=Peroxisomal targeting signal 2 receptor; Short=PTS2 receptor; AltName: Full=Peroxin-7;+++[Q5TDQ5_HUMAN|Unreviewed]SubName: Full=Peroxisomal targeting signal 2 receptor {ECO:0000313|Ensembl:ENSP00000356730};+++[Q6FGN1_HUMAN|Unreviewed]SubName: Full=PEX7 protein {ECO:0000313|EMBL:CAG46873.1}; SubName: Full=Peroxisomal biogenesis factor 7, isoform CRA_a {ECO:0000313|EMBL:EAW47940.1};"]
[5211,"'PFKL'",4281,3899,4218,4132.66666666667,"04152///AMPK signaling pathway+++00680///Methane metabolism+++01100///Metabolic pathways+++03018///RNA degradation+++05230///Central carbon metabolism in cancer+++01110///Biosynthesis of secondary metabolites+++01230///Biosynthesis of amino acids+++00010///Glycolysis / Gluconeogenesis+++01120///Microbial metabolism in diverse environments+++00051///Fructose and mannose metabolism+++01130///Biosynthesis of antibiotics+++00030///Pentose phosphate pathway+++01200///Carbon metabolism+++00052///Galactose metabolism","H01762///Muscle glycogen storage disease+++H01945///Glycogen storage disease type VII+++H00069///Glycogen storage diseases (GSD)","M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate+++M00345///Formaldehyde assimilation, ribulose monophosphate pathway","R04779///ATP:D-fructose-6-phosphate 1-phosphotransferase   ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate+++R03239///ITP:D-tagatose 6-phosphate 1-phosphotransferase   ITP + D-Tagatose 6-phosphate <=> IDP + D-Tagatose 1,6-bisphosphate+++R00756///ATP:D-fructose-6-phosphate 1-phosphotransferase   ATP + D-Fructose 6-phosphate <=> ADP + D-Fructose 1,6-bisphosphate+++R03236///ATP:D-tagatose-6-phosphate 1-phosphotransferase   D-Tagatose 6-phosphate + ATP <=> D-Tagatose 1,6-bisphosphate + ADP+++R03238///UTP:D-tagatose 6-phosphate 1-phosphotransferase   UTP + D-Tagatose 6-phosphate <=> UDP + D-Tagatose 1,6-bisphosphate+++R03237///CTP:D-tagatose 6-phosphate 1-phosphotransferase   CTP + D-Tagatose 6-phosphate <=> CDP + D-Tagatose 1,6-bisphosphate","GO:0005737///cytoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005945///6-phosphofructokinase complex+++GO:0016020///membrane+++GO:0034774///secretory granule lumen+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0048029///monosaccharide binding+++GO:0070095///fructose-6-phosphate binding+++GO:0070061///fructose binding+++GO:0042802///identical protein binding+++GO:0003872///6-phosphofructokinase activity+++GO:0016208///AMP binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003824///catalytic activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0019900///kinase binding+++GO:0016740///transferase activity","GO:0016310///phosphorylation+++GO:0051259///protein complex oligomerization+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0009749///response to glucose+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0046676///negative regulation of insulin secretion+++GO:0051289///protein homotetramerization+++GO:0005975///carbohydrate metabolic process+++GO:0061615///glycolytic process through fructose-6-phosphate+++GO:0043312///neutrophil degranulation+++GO:0006007///glucose catabolic process+++GO:0061621///canonical glycolysis+++GO:0008152///metabolic process+++GO:0006096///glycolytic process","phosphofructokinase, liver type","[PFKAL_HUMAN|Reviewed]RecName: Full=ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255|HAMAP-Rule:MF_03184}; Short=ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184}; Short=PFK-L; EC=2.7.1.11 {ECO:0000255|HAMAP-Rule:MF_03184}; AltName: Full=6-phosphofructokinase type B; AltName: Full=Phosphofructo-1-kinase isozyme B; Short=PFK-B; AltName: Full=Phosphohexokinase {ECO:0000255|HAMAP-Rule:MF_03184};+++[F8WEU2_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, liver type {ECO:0000313|Ensembl:ENSP00000381052};+++[Q7L2M7_HUMAN|Unreviewed]SubName: Full=PFKL protein {ECO:0000313|EMBL:AAH18295.2}; Flags: Fragment;+++[Q9BSP4_HUMAN|Unreviewed]SubName: Full=PFKL protein {ECO:0000313|EMBL:AAH04920.2}; Flags: Fragment;"]
[523,"'ATP6V1A'",1367,1374.02,1065,1268.67333333333,"05110///Vibrio cholerae infection+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04145///Phagosome+++04150///mTOR signaling pathway+++05323///Rheumatoid arthritis+++04721///Synaptic vesicle cycle+++05165///Human papillomavirus infection+++00190///Oxidative phosphorylation+++04966///Collecting duct acid secretion+++01100///Metabolic pathways","H02150///Infantile or early childhood epileptic encephalopathy","M00160///V-type ATPase, eukaryotes",null,"GO:0016324///apical plasma membrane+++GO:0070062///extracellular exosome+++GO:0043209///myelin sheath+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0016469///proton-transporting two-sector ATPase complex+++GO:0033180///proton-transporting V-type ATPase, V1 domain+++GO:0005886///plasma membrane+++GO:0005774///vacuolar membrane+++GO:0005902///microvillus","GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0033572///transferrin transport+++GO:0046034///ATP metabolic process+++GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:0008286///insulin receptor signaling pathway+++GO:0036295///cellular response to increased oxygen levels+++GO:0015991///ATP hydrolysis coupled proton transport+++GO:0016241///regulation of macroautophagy","ATPase H+ transporting V1 subunit A","[VATA_HUMAN|Reviewed]RecName: Full=V-type proton ATPase catalytic subunit A; Short=V-ATPase subunit A; EC=3.6.3.14; AltName: Full=V-ATPase 69 kDa subunit; AltName: Full=Vacuolar ATPase isoform VA68; AltName: Full=Vacuolar proton pump subunit alpha;+++[C9JA17_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase catalytic subunit A {ECO:0000313|Ensembl:ENSP00000417545}; Flags: Fragment;+++[C9JVW8_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase catalytic subunit A {ECO:0000313|Ensembl:ENSP00000419294}; Flags: Fragment;+++[F8WDJ3_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase catalytic subunit A {ECO:0000313|Ensembl:ENSP00000420146};"]
[5264,"'PHYH'",292,244,242,259.333333333333,"04146///Peroxisome","H00075///Refsum disease",null,null,"GO:0005782///peroxisomal matrix+++GO:0005829///cytosol+++GO:0005777///peroxisome","GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0003824///catalytic activity+++GO:0031418///L-ascorbic acid binding+++GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding+++GO:0048244///phytanoyl-CoA dioxygenase activity+++GO:0031406///carboxylic acid binding+++GO:0048037///cofactor binding+++GO:0016491///oxidoreductase activity","GO:0001561///fatty acid alpha-oxidation+++GO:0055114///oxidation-reduction process+++GO:0006625///protein targeting to peroxisome+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006720///isoprenoid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0097089///methyl-branched fatty acid metabolic process","phytanoyl-CoA 2-hydroxylase","[PAHX_HUMAN|Reviewed]RecName: Full=Phytanoyl-CoA dioxygenase, peroxisomal; EC=1.14.11.18; AltName: Full=Phytanic acid oxidase; AltName: Full=Phytanoyl-CoA alpha-hydroxylase; Short=PhyH; Flags: Precursor;+++[B1ALH6_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA dioxygenase, peroxisomal {ECO:0000313|Ensembl:ENSP00000380126};+++[C9IYS5_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA dioxygenase, peroxisomal {ECO:0000313|Ensembl:ENSP00000412525}; Flags: Fragment;+++[C9JR86_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA dioxygenase, peroxisomal {ECO:0000313|Ensembl:ENSP00000420117}; Flags: Fragment;+++[Q6FGQ2_HUMAN|Unreviewed]SubName: Full=PHYH protein {ECO:0000313|EMBL:CAG46852.1}; Flags: Fragment;"]
[5276,"'SERPINI2'",4,3,2,3,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome","GO:0030414///peptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0005515///protein binding","GO:0010951///negative regulation of endopeptidase activity+++GO:0030155///regulation of cell adhesion+++GO:0010466///negative regulation of peptidase activity","serpin family I member 2","[SPI2_HUMAN|Reviewed]RecName: Full=Serpin I2; AltName: Full=Myoepithelium-derived serine protease inhibitor; AltName: Full=Pancpin; AltName: Full=Pancreas-specific protein TSA2004; AltName: Full=Peptidase inhibitor 14; Short=PI-14; Flags: Precursor;+++[A0A0C4DGW9_HUMAN|Unreviewed]SubName: Full=Serpin I2 {ECO:0000313|Ensembl:ENSP00000481699};+++[B4DDY9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56490, highly similar to Serpin I2 {ECO:0000313|EMBL:BAG56900.1};+++[C9J7N5_HUMAN|Unreviewed]SubName: Full=Serpin I2 {ECO:0000313|Ensembl:ENSP00000417752}; Flags: Fragment;+++[C9JWE1_HUMAN|Unreviewed]SubName: Full=Serpin I2 {ECO:0000313|Ensembl:ENSP00000419255}; Flags: Fragment;"]
[5284,"'PIGR'",1.94,3,1,1.98,"04672///Intestinal immune network for IgA production",{"$nulls":3},"GO:0005576///extracellular region+++GO:0043235///receptor complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0035577///azurophil granule membrane+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome","GO:0001792///polymeric immunoglobulin receptor activity","GO:0002415///immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0043113///receptor clustering+++GO:0001895///retina homeostasis+++GO:0038093///Fc receptor signaling pathway+++GO:0043312///neutrophil degranulation","polymeric immunoglobulin receptor","[PIGR_HUMAN|Reviewed]RecName: Full=Polymeric immunoglobulin receptor; Short=PIgR; Short=Poly-Ig receptor; AltName: Full=Hepatocellular carcinoma-associated protein TB6; Contains: RecName: Full=Secretory component; Flags: Precursor;+++[Q8TE27_HUMAN|Unreviewed]SubName: Full=Polymeric immunoglobulin receptor {ECO:0000313|EMBL:AAF72193.1}; Flags: Fragment;"]
[5316,"'PKNOX1'",259,270,259,262.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006366///transcription by RNA polymerase II+++GO:0030217///T cell differentiation+++GO:0030218///erythrocyte differentiation+++GO:0001525///angiogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030097///hemopoiesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043010///camera-type eye development","PBX/knotted 1 homeobox 1","[PKNX1_HUMAN|Reviewed]RecName: Full=Homeobox protein PKNOX1; AltName: Full=Homeobox protein PREP-1; AltName: Full=PBX/knotted homeobox 1;+++[B4DGV5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53736, highly similar to Homeobox protein PKNOX1 {ECO:0000313|EMBL:BAG57916.1};+++[E7EPN6_HUMAN|Unreviewed]SubName: Full=Homeobox protein PKNOX1 {ECO:0000313|Ensembl:ENSP00000402243};+++[H0YM69_HUMAN|Unreviewed]SubName: Full=Homeobox protein PKNOX1 {ECO:0000313|Ensembl:ENSP00000453486};+++[Q6PKH2_HUMAN|Unreviewed]SubName: Full=PKNOX1 protein {ECO:0000313|EMBL:AAH00735.1}; Flags: Fragment;+++[Q96I87_HUMAN|Unreviewed]SubName: Full=Homeobox-containing protein PKNOX1 {ECO:0000313|EMBL:AAO45825.1}; SubName: Full=PBX/knotted 1 homeobox 1 {ECO:0000313|EMBL:AAH07746.1}; SubName: Full=PBX/knotted 1 homeobox 1, isoform CRA_b {ECO:0000313|EMBL:EAX09518.1};"]
[5324,"'PLAG1'",149,99,83,110.333333333333,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0060736///prostate gland growth+++GO:0006351///transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:0006355///regulation of transcription, DNA-templated+++GO:0022612///gland morphogenesis+++GO:0010629///negative regulation of gene expression+++GO:0035265///organ growth+++GO:0035264///multicellular organism growth+++GO:0060252///positive regulation of glial cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II","PLAG1 zinc finger","[PLAG1_HUMAN|Reviewed]RecName: Full=Zinc finger protein PLAG1; AltName: Full=Pleiomorphic adenoma gene 1 protein;+++[A0A024R7Z0_HUMAN|Unreviewed]SubName: Full=Pleiomorphic adenoma gene 1, isoform CRA_a {ECO:0000313|EMBL:EAW86775.1};+++[A7IT79_HUMAN|Unreviewed]SubName: Full=CHCHD7-PLAG1 fusion protein {ECO:0000313|EMBL:ABF48561.1}; Flags: Fragment;+++[A7IT80_HUMAN|Unreviewed]SubName: Full=CHCHD7-PLAG1 fusion protein {ECO:0000313|EMBL:ABF48562.1}; Flags: Fragment;"]
[5336,"'PLCG2'",82,114,84,93.3333333333333,"04750///Inflammatory mediator regulation of TRP channels+++05225///Hepatocellular carcinoma+++04664///Fc epsilon RI signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04919///Thyroid hormone signaling pathway+++04370///VEGF signaling pathway+++04360///Axon guidance+++05223///Non-small cell lung cancer+++00562///Inositol phosphate metabolism+++04933///AGE-RAGE signaling pathway in diabetic complications+++04012///ErbB signaling pathway+++04070///Phosphatidylinositol signaling system+++04380///Osteoclast differentiation+++04064///NF-kappa B signaling pathway+++04014///Ras signaling pathway+++05205///Proteoglycans in cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04650///Natural killer cell mediated cytotoxicity+++05169///Epstein-Barr virus infection+++04722///Neurotrophin signaling pathway+++04662///B cell receptor signaling pathway+++04066///HIF-1 signaling pathway+++04670///Leukocyte transendothelial migration+++04666///Fc gamma R-mediated phagocytosis+++01100///Metabolic pathways+++04611///Platelet activation+++05206///MicroRNAs in cancer+++04625///C-type lectin receptor signaling pathway+++05110///Vibrio cholerae infection+++05214///Glioma+++05200///Pathways in cancer+++04072///Phospholipase D signaling pathway+++04020///Calcium signaling pathway","H01743///Autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation (APLAID)","M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R03332///1-Phosphatidyl-D-myo-inositol inositolphosphohydrolase   1-Phosphatidyl-D-myo-inositol + H2O <=> Inositol 1-phosphate + 1,2-Diacyl-sn-glycerol+++R10952///1-phosphatidyl-1D-myo-inositol-4-phosphate inositolbisphosphohydrolase   1-Phosphatidyl-1D-myo-inositol 4-phosphate + H2O <=> 1D-myo-Inositol 1,4-bisphosphate + 1,2-Diacyl-sn-glycerol+++R03435///1-Phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase   1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol","GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0004435///phosphatidylinositol phospholipase C activity+++GO:0008081///phosphoric diester hydrolase activity+++GO:0004629///phospholipase C activity+++GO:0001784///phosphotyrosine residue binding+++GO:0016787///hydrolase activity","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007165///signal transduction+++GO:0032481///positive regulation of type I interferon production+++GO:0002316///follicular B cell differentiation+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0010468///regulation of gene expression+++GO:0043647///inositol phosphate metabolic process+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0009395///phospholipid catabolic process+++GO:0016055///Wnt signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0002092///positive regulation of receptor internalization+++GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0030168///platelet activation+++GO:0035556///intracellular signal transduction+++GO:0050852///T cell receptor signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0030183///B cell differentiation+++GO:0019722///calcium-mediated signaling+++GO:0032237///activation of store-operated calcium channel activity+++GO:0050853///B cell receptor signaling pathway+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0043069///negative regulation of programmed cell death","phospholipase C gamma 2","[PLCG2_HUMAN|Reviewed]RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; EC=3.1.4.11; AltName: Full=Phosphoinositide phospholipase C-gamma-2; AltName: Full=Phospholipase C-IV; Short=PLC-IV; AltName: Full=Phospholipase C-gamma-2; Short=PLC-gamma-2;+++[A0A0A0MRF9_HUMAN|Unreviewed]RecName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma {ECO:0000256|PIRNR:PIRNR000952}; EC=3.1.4.11 {ECO:0000256|PIRNR:PIRNR000952};+++[H3BMT7_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 {ECO:0000313|Ensembl:ENSP00000454536}; Flags: Fragment;+++[H3BPZ3_HUMAN|Unreviewed]RecName: Full=Phosphoinositide phospholipase C {ECO:0000256|RuleBase:RU361133}; EC=3.1.4.11 {ECO:0000256|RuleBase:RU361133}; Flags: Fragment;+++[H3BQV5_HUMAN|Unreviewed]SubName: Full=1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 {ECO:0000313|Ensembl:ENSP00000455956}; Flags: Fragment;"]
[53405,"'CLIC5'",10,2,2,4.66666666666667,"00230///Purine metabolism",null,null,"R00187///P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase P1,P3-Bis(5'-adenosyl) triphosphate + H2O <=> ADP + AMP","GO:0016020///membrane+++GO:0034707///chloride channel complex+++GO:0005938///cell cortex+++GO:0016021///integral component of membrane+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0015629///actin cytoskeleton","GO:0005515///protein binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005254///chloride channel activity","GO:0034220///ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0007605///sensory perception of sound+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0007565///female pregnancy+++GO:1902476///chloride transmembrane transport","chloride intracellular channel 5","[CLIC5_HUMAN|Reviewed]RecName: Full=Chloride intracellular channel protein 5;+++[A0A2R8Y4M1_HUMAN|Unreviewed]SubName: Full=Chloride intracellular channel protein 5 {ECO:0000313|Ensembl:ENSP00000493894};+++[A0A2R8Y615_HUMAN|Unreviewed]RecName: Full=Chloride intracellular channel protein {ECO:0000256|RuleBase:RU362009};+++[A0A2R8YGW2_HUMAN|Unreviewed]SubName: Full=Chloride intracellular channel protein 5 {ECO:0000313|Ensembl:ENSP00000496359};+++[Q49AE1_HUMAN|Unreviewed]SubName: Full=CLIC5 protein {ECO:0000313|EMBL:AAH39380.1};+++[Q53G01_HUMAN|Unreviewed]RecName: Full=Chloride intracellular channel protein {ECO:0000256|RuleBase:RU362009}; Flags: Fragment;+++[Q7Z2R8_HUMAN|Unreviewed]SubName: Full=MSTP130 {ECO:0000313|EMBL:AAQ13664.1};+++[Q8N675_HUMAN|Unreviewed]SubName: Full=CLIC5 protein {ECO:0000313|EMBL:AAH20923.1};"]
[53635,"'PTOV1'",3033,2827,3252,3037.33333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm",null,"GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","prostate tumor overexpressed 1","[PTOV1_HUMAN|Reviewed]RecName: Full=Prostate tumor-overexpressed gene 1 protein; Short=PTOV-1; AltName: Full=Activator interaction domain-containing protein 2;+++[A0A0C4DGR2_HUMAN|Unreviewed]SubName: Full=Prostate tumor overexpressed gene 1, isoform CRA_d {ECO:0000313|EMBL:EAW52555.1}; SubName: Full=Prostate tumor-overexpressed gene 1 protein {ECO:0000313|Ensembl:ENSP00000471458};+++[B4DG17_HUMAN|Unreviewed]SubName: Full=Prostate tumor overexpressed gene 1, isoform CRA_e {ECO:0000313|EMBL:EAW52556.1}; SubName: Full=cDNA FLJ58135, highly similar to Homo sapiens prostate tumor overexpressed gene 1 (PTOV1), mRNA {ECO:0000313|EMBL:BAG57628.1};+++[M0QX53_HUMAN|Unreviewed]SubName: Full=Prostate tumor-overexpressed gene 1 protein {ECO:0000313|Ensembl:ENSP00000468905}; Flags: Fragment;+++[M0QY25_HUMAN|Unreviewed]SubName: Full=Prostate tumor-overexpressed gene 1 protein {ECO:0000313|Ensembl:ENSP00000469541};+++[M0QYH6_HUMAN|Unreviewed]SubName: Full=Prostate tumor-overexpressed gene 1 protein {ECO:0000313|Ensembl:ENSP00000469838}; Flags: Fragment;+++[M0QYH7_HUMAN|Unreviewed]SubName: Full=Prostate tumor-overexpressed gene 1 protein {ECO:0000313|Ensembl:ENSP00000469839}; Flags: Fragment;+++[M0QYQ4_HUMAN|Unreviewed]SubName: Full=Prostate tumor overexpressed gene 1, isoform CRA_i {ECO:0000313|EMBL:EAW52560.1}; SubName: Full=Prostate tumor-overexpressed gene 1 protein {ECO:0000313|Ensembl:ENSP00000470007};+++[M0QZB9_HUMAN|Unreviewed]SubName: Full=Prostate tumor-overexpressed gene 1 protein {ECO:0000313|Ensembl:ENSP00000470439}; Flags: Fragment;"]
[5375,"'PMP2'",4,2,2,2.66666666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath","GO:0015485///cholesterol binding+++GO:0008289///lipid binding+++GO:0005504///fatty acid binding+++GO:0005515///protein binding","GO:0061024///membrane organization","peripheral myelin protein 2","[MYP2_HUMAN|Reviewed]RecName: Full=Myelin P2 protein; AltName: Full=Peripheral myelin protein 2;+++[E5RH45_HUMAN|Unreviewed]SubName: Full=Myelin P2 protein {ECO:0000313|Ensembl:ENSP00000429917};"]
[5393,"'EXOSC9'",269,317,320,302,"03018///RNA degradation",null,"M00391///Exosome, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0000228///nuclear chromosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005730///nucleolus+++GO:0000176///nuclear exosome (RNase complex)+++GO:0000178///exosome (RNase complex)+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0000177///cytoplasmic exosome (RNase complex)","GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0017091///AU-rich element binding+++GO:0005515///protein binding+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0004532///exoribonuclease activity+++GO:0003723///RNA binding","GO:0034473///U1 snRNA 3'-end processing+++GO:0043488///regulation of mRNA stability+++GO:0071038///nuclear polyadenylation-dependent tRNA catabolic process+++GO:0006364///rRNA processing+++GO:0034427///nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'+++GO:0006955///immune response+++GO:0034475///U4 snRNA 3'-end processing+++GO:0016075///rRNA catabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071035///nuclear polyadenylation-dependent rRNA catabolic process+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0071028///nuclear mRNA surveillance+++GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process+++GO:0034476///U5 snRNA 3'-end processing+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0030307///positive regulation of cell growth+++GO:0000467///exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006396///RNA processing","exosome component 9","[EXOS9_HUMAN|Reviewed]RecName: Full=Exosome complex component RRP45; AltName: Full=Autoantigen PM/Scl 1; AltName: Full=Exosome component 9; AltName: Full=P75 polymyositis-scleroderma overlap syndrome-associated autoantigen; AltName: Full=Polymyositis/scleroderma autoantigen 1; AltName: Full=Polymyositis/scleroderma autoantigen 75 kDa; Short=PM/Scl-75;+++[A0A060APE7_HUMAN|Unreviewed]SubName: Full=p5 protein {ECO:0000313|EMBL:AIA66845.1};+++[A5PLM5_HUMAN|Unreviewed]SubName: Full=Exosome component 9 {ECO:0000313|EMBL:AAI42979.1};+++[B4DXG8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55260, highly similar to Exosome complex exonuclease RRP45 {ECO:0000313|EMBL:BAG63380.1};+++[D6R905_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP45 {ECO:0000313|Ensembl:ENSP00000422205}; Flags: Fragment;+++[D6RA17_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP45 {ECO:0000313|Ensembl:ENSP00000423476}; SubName: Full=Exosome component 9, isoform CRA_e {ECO:0000313|EMBL:EAX05251.1};+++[D6RAP4_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP45 {ECO:0000313|Ensembl:ENSP00000421845};+++[D6RIY6_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP45 {ECO:0000313|Ensembl:ENSP00000425782}; SubName: Full=Exosome component 9, isoform CRA_f {ECO:0000313|EMBL:EAX05252.1};+++[H0Y9L5_HUMAN|Unreviewed]SubName: Full=Exosome complex component RRP45 {ECO:0000313|Ensembl:ENSP00000424504}; Flags: Fragment;"]
[540,"'ATP7B'",301,289,196,262,"01524///Platinum drug resistance+++04016///MAPK signaling pathway - plant","H00856///Distal hereditary motor neuropathies (dHMN)+++H00210///Wilson disease+++H00209///Menkes syndrome+++H01859///Occipital horn syndrome+++H00455///Spinal muscular atrophy (SMA)",null,"R00086///ATP phosphohydrolase   ATP + H2O <=> ADP + Orthophosphate","GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0016323///basolateral plasma membrane+++GO:0005770///late endosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0031410///cytoplasmic vesicle+++GO:0005887///integral component of plasma membrane+++GO:0005768///endosome+++GO:0005739///mitochondrion+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0004008///copper-exporting ATPase activity+++GO:0005375///copper ion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0005507///copper ion binding+++GO:0019829///cation-transporting ATPase activity+++GO:0043682///copper-transporting ATPase activity+++GO:0046872///metal ion binding","GO:0006811///ion transport+++GO:0006825///copper ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0030001///metal ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0007595///lactation+++GO:0035434///copper ion transmembrane transport+++GO:0046688///response to copper ion+++GO:0034220///ion transmembrane transport+++GO:0015677///copper ion import+++GO:0051208///sequestering of calcium ion+++GO:0060003///copper ion export+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006812///cation transport+++GO:0015680///protein maturation by copper ion transfer","ATPase copper transporting beta","[ATP7B_HUMAN|Reviewed]RecName: Full=Copper-transporting ATPase 2; EC=3.6.3.54 {ECO:0000269|PubMed:22240481}; AltName: Full=Copper pump 2; AltName: Full=Wilson disease-associated protein; Contains: RecName: Full=WND/140 kDa {ECO:0000303|PubMed:9600907};+++[A0A024RDX3_HUMAN|Unreviewed]SubName: Full=ATPase, Cu++ transporting, beta polypeptide, isoform CRA_c {ECO:0000313|EMBL:EAX08896.1};+++[A0A0U1RQY8_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000489234};+++[A0A0U1RRG1_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000489512}; Flags: Fragment;+++[A0A2Z5ENW8_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87956.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87956.1}; Flags: Fragment;+++[A0A2Z5ENX0_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87958.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87958.1}; Flags: Fragment;+++[A0A2Z5ENX2_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87959.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87959.1}; Flags: Fragment;+++[A0A2Z5ENX4_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87957.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87957.1}; Flags: Fragment;+++[A0A2Z5ENX7_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87961.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87961.1}; Flags: Fragment;+++[A0A2Z5ENX9_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87962.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87962.1}; Flags: Fragment;+++[A0A2Z5ENY1_HUMAN|Unreviewed]SubName: Full=Copper-transporting protein ATP7B {ECO:0000313|EMBL:AXB87960.1}; EC=3.6.3.54 {ECO:0000313|EMBL:AXB87960.1}; Flags: Fragment;+++[A1YIY1_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:ABL98127.1}; Flags: Fragment;+++[A6N865_HUMAN|Unreviewed]SubName: Full=Cu++ transporting ATPase beta polypeptide {ECO:0000313|EMBL:ABR10903.1}; Flags: Fragment;+++[A6YQZ0_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide {ECO:0000313|EMBL:ABR92758.1}; Flags: Fragment;+++[A6YQZ1_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide {ECO:0000313|EMBL:ABR92759.1}; Flags: Fragment;+++[A7UDR4_HUMAN|Unreviewed]SubName: Full=ATPase 7B {ECO:0000313|EMBL:ABU46397.1}; Flags: Fragment;+++[B7ZLR2_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI43974.1};+++[B7ZLR3_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI43976.1};+++[B7ZLR4_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI43977.1}; SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000489398};+++[C0LF55_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:ACN65027.1}; EC=3.6.3.4 {ECO:0000313|EMBL:ACN65027.1}; Flags: Fragment;+++[C8BMD5_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide variant {ECO:0000313|EMBL:ACU56999.1}; EC=3.6.3.4 {ECO:0000313|EMBL:ACU56999.1}; Flags: Fragment;+++[D3KCZ0_HUMAN|Unreviewed]SubName: Full=Mutant ATP7B {ECO:0000313|EMBL:ADC29645.1}; Flags: Fragment;+++[E7ET55_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000416738};+++[F5H562_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000383221};+++[F5H748_HUMAN|Unreviewed]SubName: Full=Copper-transporting ATPase 2 {ECO:0000313|Ensembl:ENSP00000393343};+++[G1FFE8_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82632.1}; Flags: Fragment;+++[G1FFE9_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82633.1}; Flags: Fragment;+++[G1FFF0_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82634.1}; Flags: Fragment;+++[G1FFF1_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82635.1}; Flags: Fragment;+++[G1FFF2_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82636.1}; Flags: Fragment;+++[G1FFF3_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AEJ82637.1}; Flags: Fragment;+++[G8FXH4_HUMAN|Unreviewed]SubName: Full=ATPase Cu++ transporting beta polypeptide {ECO:0000313|EMBL:AER34938.1}; EC=3.6.3.4 {ECO:0000313|EMBL:AER34938.1}; Flags: Fragment;+++[Q17RT3_HUMAN|Unreviewed]SubName: Full=ATP7B protein {ECO:0000313|EMBL:AAI17201.1};+++[Q52RG2_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84215.1}; Flags: Fragment;+++[Q52RG3_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84214.1}; Flags: Fragment;+++[Q52RG4_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84213.1}; Flags: Fragment;+++[Q52RG5_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84212.1}; Flags: Fragment;+++[Q52RG6_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAX84211.1}; Flags: Fragment;+++[Q9GZP5_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27537.1}; Flags: Fragment;+++[Q9HBD5_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27543.1}; Flags: Fragment;+++[Q9HBD6_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27542.1}; Flags: Fragment;+++[Q9HBD7_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27540.1}; Flags: Fragment;+++[Q9HBD8_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27539.1}; Flags: Fragment;+++[Q9HBD9_HUMAN|Unreviewed]SubName: Full=ATP7B {ECO:0000313|EMBL:AAG27538.1}; Flags: Fragment;"]
[54107,"'POLE3'",779,832,825,812,"01100///Metabolic pathways+++00230///Purine metabolism+++03030///DNA replication+++00240///Pyrimidine metabolism+++03410///Base excision repair+++05166///HTLV-I infection+++03420///Nucleotide excision repair",null,"M00263///DNA polymerase epsilon complex","R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dGTP + DNA <=> Diphosphate + DNA+++R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dTTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dATP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dCTP + DNA <=> Diphosphate + DNA","GO:0005634///nucleus+++GO:0008622///epsilon DNA polymerase complex+++GO:0005654///nucleoplasm+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex","GO:0003887///DNA-directed DNA polymerase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0016779///nucleotidyltransferase activity+++GO:0016740///transferase activity+++GO:0004402///histone acetyltransferase activity+++GO:0046982///protein heterodimerization activity","GO:0071480///cellular response to gamma radiation+++GO:0043966///histone H3 acetylation+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0006260///DNA replication+++GO:0042766///nucleosome mobilization+++GO:0070869///heterochromatin assembly involved in chromatin silencing+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0071897///DNA biosynthetic process","DNA polymerase epsilon 3, accessory subunit","[DPOE3_HUMAN|Reviewed]RecName: Full=DNA polymerase epsilon subunit 3; EC=2.7.7.7; AltName: Full=Arsenic-transactivated protein; Short=AsTP; AltName: Full=Chromatin accessibility complex 17 kDa protein; Short=CHRAC-17; Short=HuCHRAC17; AltName: Full=DNA polymerase II subunit 3; AltName: Full=DNA polymerase epsilon subunit p17;+++[A0A024R829_HUMAN|Unreviewed]SubName: Full=Polymerase (DNA directed), epsilon 3 (P17 subunit), isoform CRA_a {ECO:0000313|EMBL:EAW87382.1};"]
[5423,"'POLB'",96,123,123,114,"05203///Viral carcinogenesis+++05166///HTLV-I infection+++03410///Base excision repair",null,"M00296///BER complex",null,"GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005876///spindle microtubule+++GO:0005654///nucleoplasm+++GO:0005874///microtubule","GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0008017///microtubule binding+++GO:0046872///metal ion binding+++GO:0003684///damaged DNA binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0019899///enzyme binding+++GO:0016829///lyase activity","GO:0006287///base-excision repair, gap-filling+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0045471///response to ethanol+++GO:0048535///lymph node development+++GO:0007568///aging+++GO:0051402///neuron apoptotic process+++GO:0006288///base-excision repair, DNA ligation+++GO:0010332///response to gamma radiation+++GO:0016579///protein deubiquitination+++GO:0007435///salivary gland morphogenesis+++GO:0006281///DNA repair+++GO:0006954///inflammatory response+++GO:0006261///DNA-dependent DNA replication+++GO:0006286///base-excision repair, base-free sugar-phosphate removal+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0006290///pyrimidine dimer repair+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0048536///spleen development+++GO:0071707///immunoglobulin heavy chain V-D-J recombination+++GO:0048872///homeostasis of number of cells+++GO:0055093///response to hyperoxia","DNA polymerase beta","[DPOLB_HUMAN|Reviewed]RecName: Full=DNA polymerase beta; EC=2.7.7.7; EC=4.2.99.-;+++[B7Z1W5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57297, highly similar to DNA polymerase beta {ECO:0000313|EMBL:BAH11651.1};"]
[54329,"'GPR85'",11,8,10,9.66666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","G protein-coupled receptor 85","[GPR85_HUMAN|Reviewed]RecName: Full=Probable G-protein coupled receptor 85; AltName: Full=Super conserved receptor expressed in brain 2;+++[A4D0T8_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 85 {ECO:0000313|EMBL:EAL24372.1}; SubName: Full=cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA {ECO:0000313|EMBL:BAG35481.1};+++[C9JBQ9_HUMAN|Unreviewed]SubName: Full=Probable G-protein-coupled receptor 85 {ECO:0000313|Ensembl:ENSP00000415699}; Flags: Fragment;+++[C9JDK8_HUMAN|Unreviewed]SubName: Full=Probable G-protein-coupled receptor 85 {ECO:0000313|Ensembl:ENSP00000416722}; Flags: Fragment;+++[Q8NEN2_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 85 {ECO:0000313|EMBL:AAH30577.1};"]
[5442,"'POLRMT'",1024,1031,1087,1047.33333333333,{"$nulls":4},"GO:0034245///mitochondrial DNA-directed RNA polymerase complex+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0042645///mitochondrial nucleoid+++GO:0032991///protein-containing complex","GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0001018///mitochondrial promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding","GO:0006390///mitochondrial transcription+++GO:0006351///transcription, DNA-templated+++GO:0007005///mitochondrion organization+++GO:0006391///transcription initiation from mitochondrial promoter","RNA polymerase mitochondrial","[RPOM_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase, mitochondrial; Short=MtRPOL; EC=2.7.7.6; Flags: Precursor;+++[K7EMH3_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466504}; Flags: Fragment;+++[K7ESD1_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase, mitochondrial {ECO:0000313|Ensembl:ENSP00000468658}; Flags: Fragment;+++[Q4G0F4_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase {ECO:0000256|RuleBase:RU003805}; EC=2.7.7.6 {ECO:0000256|RuleBase:RU003805};+++[R4GN79_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase, mitochondrial {ECO:0000313|Ensembl:ENSP00000473524};"]
[54453,"'RIN2'",950,824,704,826,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005575///cellular_component","GO:0030695///GTPase regulator activity+++GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0006897///endocytosis+++GO:0007264///small GTPase mediated signal transduction+++GO:0007049///cell cycle+++GO:0043547///positive regulation of GTPase activity","Ras and Rab interactor 2","[RIN2_HUMAN|Reviewed]RecName: Full=Ras and Rab interactor 2; AltName: Full=Ras association domain family 4; AltName: Full=Ras inhibitor JC265; AltName: Full=Ras interaction/interference protein 2;+++[A1A4T0_HUMAN|Unreviewed]SubName: Full=RIN2 protein {ECO:0000313|EMBL:AAI28066.1};+++[E7EPJ1_HUMAN|Unreviewed]SubName: Full=Ras and Rab interactor 2 {ECO:0000313|Ensembl:ENSP00000391239};"]
[54456,"'MOV10L1'",52,64,48.63,54.8766666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043186///P granule+++GO:0071546///pi-body","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0004386///helicase activity","GO:0034587///piRNA metabolic process+++GO:0007141///male meiosis I+++GO:0007281///germ cell development+++GO:0007275///multicellular organism development+++GO:0043046///DNA methylation involved in gamete generation+++GO:0007283///spermatogenesis+++GO:0035194///posttranscriptional gene silencing by RNA","Mov10 like RISC complex RNA helicase 1","[M10L1_HUMAN|Reviewed]RecName: Full=RNA helicase Mov10l1 {ECO:0000305}; EC=3.6.4.13 {ECO:0000250|UniProtKB:Q99MV5}; AltName: Full=Moloney leukemia virus 10-like protein 1 {ECO:0000312|HGNC:HGNC:7201}; Short=MOV10-like protein 1 {ECO:0000312|HGNC:HGNC:7201};+++[B9EIS3_HUMAN|Unreviewed]SubName: Full=Mov10l1, Moloney leukemia virus 10-like 1, homolog (Mouse) {ECO:0000313|EMBL:AAI40945.1};+++[F2Z2H1_HUMAN|Unreviewed]SubName: Full=RNA helicase Mov10l1 {ECO:0000313|Ensembl:ENSP00000410957};+++[H7C1D5_HUMAN|Unreviewed]SubName: Full=RNA helicase Mov10l1 {ECO:0000313|Ensembl:ENSP00000399776}; Flags: Fragment;+++[Q8IVP3_HUMAN|Unreviewed]SubName: Full=MOV10L1 protein {ECO:0000313|EMBL:AAH42828.1}; Flags: Fragment;"]
[54497,"'HEATR5B'",405,363,272,346.666666666667,"04141///Protein processing in endoplasmic reticulum+++04137///Mitophagy - animal+++05164///Influenza A+++05160///Hepatitis C+++05165///Human papillomavirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05168///Herpes simplex infection+++05162///Measles+++05203///Viral carcinogenesis+++04217///Necroptosis+++05169///Epstein-Barr virus infection+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0030139///endocytic vesicle+++GO:0016020///membrane","GO:0005515///protein binding","GO:0006897///endocytosis+++GO:0008104///protein localization+++GO:0042147///retrograde transport, endosome to Golgi","HEAT repeat containing 5B","[HTR5B_HUMAN|Reviewed]RecName: Full=HEAT repeat-containing protein 5B;+++[B9EK47_HUMAN|Unreviewed]SubName: Full=HEAT repeat containing 5B {ECO:0000313|EMBL:AAI50606.1};+++[H7C2X3_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 5B {ECO:0000313|Ensembl:ENSP00000408222}; Flags: Fragment;"]
[54499,"'TMCO1'",1137,1112,1146,1131.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0005262///calcium channel activity","GO:0070588///calcium ion transmembrane transport+++GO:0006811///ion transport+++GO:0032469///endoplasmic reticulum calcium ion homeostasis+++GO:0006983///ER overload response+++GO:0006816///calcium ion transport","transmembrane and coiled-coil domains 1","[TMCO1_HUMAN|Reviewed]RecName: Full=Calcium load-activated calcium channel {ECO:0000305|PubMed:27212239}; Short=CLAC channel {ECO:0000305|PubMed:27212239}; AltName: Full=Transmembrane and coiled-coil domain-containing protein 1 {ECO:0000305}; AltName: Full=Transmembrane and coiled-coil domains protein 4 {ECO:0000305}; AltName: Full=Xenogeneic cross-immune protein PCIA3 {ECO:0000303|Ref.2};+++[B7Z591_HUMAN|Unreviewed]RecName: Full=Calcium load-activated calcium channel {ECO:0000256|PIRNR:PIRNR023322}; Short=CLAC channel {ECO:0000256|PIRNR:PIRNR023322};+++[J3KS45_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000462300}; Flags: Fragment;+++[J3KTQ7_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000463105}; SubName: Full=Transmembrane and coiled-coil domains 1, isoform CRA_d {ECO:0000313|EMBL:EAW90765.1};+++[J3QQY2_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000463951}; SubName: Full=Transmembrane and coiled-coil domains 1, isoform CRA_c {ECO:0000313|EMBL:EAW90764.1};+++[J3QRB3_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000464127}; Flags: Fragment;+++[J9JIE6_HUMAN|Unreviewed]SubName: Full=Calcium load-activated calcium channel {ECO:0000313|Ensembl:ENSP00000356856}; SubName: Full=Transmembrane and coiled-coil domains 1, isoform CRA_b {ECO:0000313|EMBL:EAW90763.1};+++[L8EA41_HUMAN|Unreviewed]SubName: Full=Alternative protein TMCO1 {ECO:0000313|EMBL:CCQ43611.1};"]
[54518,"'APBB1IP'",1,2,4,2.33333333333333,"04611///Platelet activation+++04015///Rap1 signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0042101///T cell receptor complex+++GO:0016020///membrane+++GO:0030027///lamellipodium+++GO:0042995///cell projection+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0002291///T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell+++GO:0007165///signal transduction+++GO:0045785///positive regulation of cell adhesion","amyloid beta precursor protein binding family B member 1 interacting protein","[AB1IP_HUMAN|Reviewed]RecName: Full=Amyloid beta A4 precursor protein-binding family B member 1-interacting protein; AltName: Full=APBB1-interacting protein 1; AltName: Full=Proline-rich EVH1 ligand 1; Short=PREL-1; AltName: Full=Proline-rich protein 73; AltName: Full=Rap1-GTP-interacting adapter molecule; Short=RIAM; AltName: Full=Retinoic acid-responsive proline-rich protein 1; Short=RARP-1;+++[L8EB04_HUMAN|Unreviewed]SubName: Full=Alternative protein APBB1IP {ECO:0000313|EMBL:CCQ43613.1};"]
[54541,"'DDIT4'",810,863,659,777.333333333333,"04150///mTOR signaling pathway+++04140///Autophagy - animal+++04151///PI3K-Akt signaling pathway+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005622///intracellular+++GO:0005739///mitochondrion","GO:0071889///14-3-3 protein binding","GO:0008283///cell proliferation+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:1901216///positive regulation of neuron death+++GO:0032984///protein-containing complex disassembly+++GO:0030182///neuron differentiation+++GO:0001666///response to hypoxia+++GO:0009968///negative regulation of signal transduction+++GO:1902532///negative regulation of intracellular signal transduction+++GO:0001764///neuron migration+++GO:0032007///negative regulation of TOR signaling+++GO:0045820///negative regulation of glycolytic process+++GO:0006915///apoptotic process+++GO:0051607///defense response to virus+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0072593///reactive oxygen species metabolic process+++GO:0007420///brain development+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0071549///cellular response to dexamethasone stimulus","DNA damage inducible transcript 4","[DDIT4_HUMAN|Reviewed]RecName: Full=DNA damage-inducible transcript 4 protein; AltName: Full=HIF-1 responsive protein RTP801; AltName: Full=Protein regulated in development and DNA damage response 1; Short=REDD-1;+++[A0A024QZQ6_HUMAN|Unreviewed]SubName: Full=DNA-damage-inducible transcript 4, isoform CRA_a {ECO:0000313|EMBL:EAW54453.1};"]
[5457,"'POU4F1'",0,3,0,1,null,"H00604///Deafness, autosomal dominant",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm","GO:0003682///chromatin binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0051020///GTPase binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003697///single-stranded DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003714///transcription corepressor activity","GO:0007399///nervous system development+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071345///cellular response to cytokine stimulus+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0071392///cellular response to estradiol stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0021535///cell migration in hindbrain+++GO:0043069///negative regulation of programmed cell death+++GO:0021559///trigeminal nerve development+++GO:0001967///suckling behavior+++GO:0007416///synapse assembly+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0060384///innervation+++GO:0021953///central nervous system neuron differentiation+++GO:0021986///habenula development+++GO:0071158///positive regulation of cell cycle arrest+++GO:0048934///peripheral nervous system neuron differentiation+++GO:0007409///axonogenesis+++GO:0010629///negative regulation of gene expression+++GO:0043065///positive regulation of apoptotic process+++GO:2001208///negative regulation of transcription elongation by RNA polymerase I+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0043066///negative regulation of apoptotic process+++GO:0051355///proprioception involved in equilibrioception+++GO:0007275///multicellular organism development+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0007507///heart development+++GO:0050767///regulation of neurogenesis+++GO:0048665///neuron fate specification+++GO:0048935///peripheral nervous system neuron development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048880///sensory system development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0007498///mesoderm development","POU class 4 homeobox 1","[PO4F1_HUMAN|Reviewed]RecName: Full=POU domain, class 4, transcription factor 1 {ECO:0000312|HGNC:HGNC:9218}; AltName: Full=Brain-specific homeobox/POU domain protein 3A; Short=Brain-3A; Short=Brn-3A; AltName: Full=Homeobox/POU domain protein RDC-1; AltName: Full=Oct-T1;"]
[5462,"'POU5F1B'",22,22.22,26,23.4066666666667,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","POU class 5 homeobox 1B","[P5F1B_HUMAN|Reviewed]RecName: Full=Putative POU domain, class 5, transcription factor 1B; AltName: Full=Oct4-pg1; AltName: Full=Octamer-binding protein 3-like; AltName: Full=Octamer-binding transcription factor 3-like;"]
[54674,"'LRRN3'",4,6,3,4.33333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0051965///positive regulation of synapse assembly","leucine rich repeat neuronal 3","[LRRN3_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat neuronal protein 3; AltName: Full=Neuronal leucine-rich repeat protein 3; Short=NLRR-3; Flags: Precursor;+++[A4D0T1_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat neuronal 3 {ECO:0000313|EMBL:EAL24380.1}; SubName: Full=Leucine rich repeat neuronal 3, isoform CRA_a {ECO:0000313|EMBL:EAW83449.1};+++[E7EW58_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat neuronal protein 3 {ECO:0000313|Ensembl:ENSP00000407927}; Flags: Fragment;+++[Q9NUU4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ11129 fis, clone PLACE1006239, weakly similar to BONE PROTEOGLYCAN II {ECO:0000313|EMBL:BAA92025.1}; Flags: Fragment;"]
[54708,"'MARCH5'",452,492,463,469,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0016740///transferase activity+++GO:0051020///GTPase binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0090140///regulation of mitochondrial fission+++GO:0051865///protein autoubiquitination+++GO:0090344///negative regulation of cell aging+++GO:0090141///positive regulation of mitochondrial fission+++GO:0070585///protein localization to mitochondrion+++GO:0000209///protein polyubiquitination","membrane associated ring-CH-type finger 5","[MARH5_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MARCH5; EC=2.3.2.27; AltName: Full=Membrane-associated RING finger protein 5; AltName: Full=Membrane-associated RING-CH protein V; Short=MARCH-V; AltName: Full=Mitochondrial ubiquitin ligase; Short=MITOL; AltName: Full=RING finger protein 153; AltName: Full=RING-type E3 ubiquitin transferase MARCH5 {ECO:0000305};"]
[54757,"'FAM20A'",109,111,72,97.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00615///Amelogenesis imperfecta",null,null,"GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005623///cell+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0043539///protein serine/threonine kinase activator activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0070166///enamel mineralization+++GO:0006468///protein phosphorylation+++GO:0055074///calcium ion homeostasis+++GO:0044691///tooth eruption+++GO:0001934///positive regulation of protein phosphorylation+++GO:0009617///response to bacterium+++GO:0031214///biomineral tissue development","FAM20A, golgi associated secretory pathway pseudokinase","[FA20A_HUMAN|Reviewed]RecName: Full=Pseudokinase FAM20A {ECO:0000305}; Flags: Precursor;+++[B7Z4Y3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57131, highly similar to Protein FAM20A {ECO:0000313|EMBL:BAH12719.1};+++[K7EIV7_HUMAN|Unreviewed]SubName: Full=Pseudokinase FAM20A {ECO:0000313|Ensembl:ENSP00000464910}; Flags: Fragment;+++[K7EQL5_HUMAN|Unreviewed]SubName: Full=Pseudokinase FAM20A {ECO:0000313|Ensembl:ENSP00000467884}; Flags: Fragment;+++[L8B8N7_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 20, member A {ECO:0000313|EMBL:BAM78535.1};+++[Q71MG5_HUMAN|Unreviewed]SubName: Full=Pseudokinase FAM20A {ECO:0000313|Ensembl:ENSP00000481085};+++[Q8IYA5_HUMAN|Unreviewed]SubName: Full=FAM20A protein {ECO:0000313|EMBL:AAH36222.1};"]
[54778,"'RNF111'",664,726,554,648,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0032184///SUMO polymer binding+++GO:0016740///transferase activity+++GO:0046332///SMAD binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0046872///metal ion binding","GO:0006281///DNA repair+++GO:0007389///pattern specification process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0031398///positive regulation of protein ubiquitination+++GO:0007275///multicellular organism development+++GO:0070911///global genome nucleotide-excision repair+++GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated","ring finger protein 111","[RN111_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Arkadia {ECO:0000305|PubMed:14657019}; EC=2.3.2.27 {ECO:0000269|PubMed:23751493}; AltName: Full=RING finger protein 111 {ECO:0000312|HGNC:HGNC:17384}; Short=hRNF111 {ECO:0000303|PubMed:23751493}; AltName: Full=RING-type E3 ubiquitin transferase Arkadia {ECO:0000305};+++[A0A024R5T5_HUMAN|Unreviewed]SubName: Full=Ring finger protein 111, isoform CRA_c {ECO:0000313|EMBL:EAW77557.1};+++[A0A024R5V6_HUMAN|Unreviewed]SubName: Full=Ring finger protein 111, isoform CRA_b {ECO:0000313|EMBL:EAW77560.1};+++[H0YKK5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Arkadia {ECO:0000313|Ensembl:ENSP00000452842}; Flags: Fragment;+++[H0YKS2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Arkadia {ECO:0000313|Ensembl:ENSP00000452919}; Flags: Fragment;+++[H0YLK9_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase Arkadia {ECO:0000313|Ensembl:ENSP00000453248}; Flags: Fragment;+++[L0R5C6_HUMAN|Unreviewed]SubName: Full=Alternative protein RNF111 {ECO:0000313|EMBL:CCO13804.1};"]
[54807,"'ZNF586'",49,34,33,38.6666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 586","[ZN586_HUMAN|Reviewed]RecName: Full=Zinc finger protein 586;+++[M0QZ99_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 586 {ECO:0000313|Ensembl:ENSP00000470397};+++[M0R166_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 586 {ECO:0000313|Ensembl:ENSP00000471663};+++[M0R336_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 586 {ECO:0000313|Ensembl:ENSP00000472972};+++[Q8N6X9_HUMAN|Unreviewed]SubName: Full=ZNF586 protein {ECO:0000313|EMBL:AAH27922.1};"]
[54820,"'NDE1'",244,210,214,222.666666666667,null,"H00268///Lissencephaly (LIS)+++H01870///Microhydranencephaly",null,null,"GO:0045202///synapse+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0000776///kinetochore+++GO:0005819///spindle+++GO:0005813///centrosome+++GO:0005871///kinesin complex+++GO:0005737///cytoplasm+++GO:0031616///spindle pole centrosome+++GO:0005694///chromosome+++GO:0032154///cleavage furrow+++GO:0000775///chromosome, centromeric region+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore","GO:0019904///protein domain specific binding+++GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0021987///cerebral cortex development+++GO:0051642///centrosome localization+++GO:0007059///chromosome segregation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:2000574///regulation of microtubule motor activity+++GO:0030900///forebrain development+++GO:0007100///mitotic centrosome separation+++GO:0051303///establishment of chromosome localization+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0007020///microtubule nucleation+++GO:0016477///cell migration+++GO:0031023///microtubule organizing center organization+++GO:0001764///neuron migration+++GO:0007049///cell cycle+++GO:0051298///centrosome duplication+++GO:0000132///establishment of mitotic spindle orientation+++GO:0047496///vesicle transport along microtubule+++GO:0007405///neuroblast proliferation+++GO:0051301///cell division+++GO:0007275///multicellular organism development+++GO:0097711///ciliary basal body-plasma membrane docking","nudE neurodevelopment protein 1","[NDE1_HUMAN|Reviewed]RecName: Full=Nuclear distribution protein nudE homolog 1; Short=NudE;+++[I3L2R3_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000459863}; Flags: Fragment;+++[I3L2R9_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000459875}; Flags: Fragment;+++[I3L2S8_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000459889}; Flags: Fragment;+++[I3L2T8_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000459918}; Flags: Fragment;+++[I3L3G9_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000460436};+++[I3L464_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000460996};+++[I3L522_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000461729}; Flags: Fragment;+++[I3L533_HUMAN|Unreviewed]SubName: Full=Nuclear distribution protein nudE homolog 1 {ECO:0000313|Ensembl:ENSP00000461748}; Flags: Fragment;+++[L8E8T4_HUMAN|Unreviewed]SubName: Full=Alternative protein NDE1 {ECO:0000313|EMBL:CCQ43564.1};+++[X5DP35_HUMAN|Unreviewed]SubName: Full=NudE neurodevelopment protein 1 isoform A {ECO:0000313|EMBL:AHW56631.1};+++[X5DR54_HUMAN|Unreviewed]SubName: Full=NudE neurodevelopment protein 1 isoform B {ECO:0000313|EMBL:AHW56527.1}; SubName: Full=NudE nuclear distribution gene E homolog 1 (A. nidulans), isoform CRA_b {ECO:0000313|EMBL:EAW53932.1}; Flags: Fragment;+++[X5DRB5_HUMAN|Unreviewed]SubName: Full=NudE neurodevelopment protein 1 isoform D {ECO:0000313|EMBL:AHW56607.1}; Flags: Fragment;+++[X5DRF9_HUMAN|Unreviewed]SubName: Full=NudE neurodevelopment protein 1 isoform C {ECO:0000313|EMBL:AHW56667.1};"]
[54850,"'FBXL12'",286,286,337,303,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0061630///ubiquitin protein ligase activity","GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016567///protein ubiquitination+++GO:0051726///regulation of cell cycle","F-box and leucine rich repeat protein 12","[FXL12_HUMAN|Reviewed]RecName: Full=F-box/LRR-repeat protein 12; AltName: Full=F-box and leucine-rich repeat protein 12; AltName: Full=F-box protein FBL12;+++[K7EIK3_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000464784};+++[K7EIR3_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000464858};+++[K7EK37_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000465439};+++[K7ELM5_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000466142};+++[K7EPN7_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000467467}; Flags: Fragment;+++[K7EPT3_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000467523};+++[K7EQJ7_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000467859};+++[K7EQY7_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000468033};+++[K7ESL6_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 12 {ECO:0000313|Ensembl:ENSP00000468766}; Flags: Fragment;+++[L8E9B2_HUMAN|Unreviewed]SubName: Full=Alternative protein FBXL12 {ECO:0000313|EMBL:CCQ42943.1};"]
[548596,"'CKMT1A'",11.06,34.8,30.11,25.3233333333333,"01100///Metabolic pathways+++00330///Arginine and proline metabolism",null,"M00047///Creatine pathway","R01881///ATP:creatine N-phosphotransferase   ATP + Creatine <=> ADP + Phosphocreatine","GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0005524///ATP binding+++GO:0004111///creatine kinase activity+++GO:0016301///kinase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0000166///nucleotide binding+++GO:0003824///catalytic activity+++GO:0016740///transferase activity","GO:0006600///creatine metabolic process+++GO:0016310///phosphorylation","creatine kinase, mitochondrial 1A","[KCRU_HUMAN|Reviewed]RecName: Full=Creatine kinase U-type, mitochondrial; EC=2.7.3.2; AltName: Full=Acidic-type mitochondrial creatine kinase; Short=Mia-CK; AltName: Full=Ubiquitous mitochondrial creatine kinase; Short=U-MtCK; Flags: Precursor;+++[C9J8F6_HUMAN|Unreviewed]SubName: Full=Creatine kinase U-type, mitochondrial {ECO:0000313|Ensembl:ENSP00000398973}; Flags: Fragment;+++[C9JT96_HUMAN|Unreviewed]SubName: Full=Creatine kinase U-type, mitochondrial {ECO:0000313|Ensembl:ENSP00000401927}; Flags: Fragment;+++[F8WCN3_HUMAN|Unreviewed]SubName: Full=Creatine kinase U-type, mitochondrial {ECO:0000313|Ensembl:ENSP00000416717};+++[F8WDP9_HUMAN|Unreviewed]SubName: Full=Creatine kinase U-type, mitochondrial {ECO:0000313|Ensembl:ENSP00000389806};"]
[54882,"'ANKHD1'",345.09,260.99,201.64,269.24,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0045087///innate immune response","ankyrin repeat and KH domain containing 1","[ANKH1_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and KH domain-containing protein 1; AltName: Full=HIV-1 Vpr-binding ankyrin repeat protein; AltName: Full=Multiple ankyrin repeats single KH domain; Short=hMASK;+++[A0A0A0MQZ8_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000297183};+++[D6RHC4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000421069}; Flags: Fragment;+++[E9PDP5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000394489}; Flags: Fragment;+++[H0Y472_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000390034}; Flags: Fragment;+++[H0Y4P6_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000393204}; Flags: Fragment;+++[H0Y785_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410959}; Flags: Fragment;+++[H0Y7Y3_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000415887}; Flags: Fragment;+++[H3BLS9_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000246149}; Flags: Fragment;+++[H7C2E1_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405345}; Flags: Fragment;+++[H7C2F5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and KH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405602}; Flags: Fragment;+++[Q8IWG5_HUMAN|Unreviewed]SubName: Full=ANKHD1 protein {ECO:0000313|EMBL:AAH40231.1};"]
[54900,"'LAX1'",5,2,0,2.33333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus","GO:0019901///protein kinase binding+++GO:0042169///SH2 domain binding+++GO:0005515///protein binding","GO:0006955///immune response+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0050868///negative regulation of T cell activation+++GO:0051249///regulation of lymphocyte activation+++GO:0000188///inactivation of MAPK activity+++GO:0042113///B cell activation+++GO:0035556///intracellular signal transduction","lymphocyte transmembrane adaptor 1","[LAX1_HUMAN|Reviewed]RecName: Full=Lymphocyte transmembrane adapter 1; AltName: Full=Linker for activation of X cells; AltName: Full=Membrane-associated adapter protein LAX;"]
[54913,"'RPP25'",77,83,87,82.3333333333333,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0005634///nucleus+++GO:0000172///ribonuclease MRP complex+++GO:0005815///microtubule organizing center+++GO:0005654///nucleoplasm+++GO:0030681///multimeric ribonuclease P complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0004526///ribonuclease P activity","GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing","ribonuclease P and MRP subunit p25","[RPP25_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p25; Short=RNase P protein subunit p25; EC=3.1.26.5;"]
[54922,"'RASIP1'",14,19,28,20.3333333333333,"04140///Autophagy - animal+++01100///Metabolic pathways+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++04137///Mitophagy - animal",null,null,"R05968///GDP-L-fucose + Galactosylgloboside <=> GDP + Globo-H+++R06041///GDP-L-fucose + G00073 <=> GDP + G00074+++R06086///GDP-L-fucose + Monofucosyllactoisooctaosylceramide <=> GDP + G00079+++R06170///Galactoside alpha-1,2-L-fucosyltransferase GDP-L-fucose + G00038 <=> GDP + Type IB glycolipid+++R06024///GDP-L-fucose + Paragloboside <=> GDP + IV2Fuc-nLc4Cer+++R06085///GDP-L-fucose + iso-nLc8Cer <=> GDP + Monofucosyllactoisooctaosylceramide+++R06027///GDP-L-fucose + nLc5Cer <=> GDP + Type II B antigen+++R06089///GDP-L-fucose + iso-nLc8Cer <=> GDP + Monofucosyllactoisooctaosylceramide+++R06090///GDP-L-fucose + Monofucosyllactoisooctaosylceramide <=> GDP + G00079+++R06156///GDP-L-fucose + Lc4Cer <=> GDP + IV2Fuc-Lc4Cer+++R06035///GDP-L-fucose + nLc6Cer <=> GDP + VI2Fuc-nLc6+++R06031///GDP-L-fucose + G00057 <=> GDP + Type IIIH glycolipid","GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005795///Golgi stack+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005911///cell-cell junction","GO:0051020///GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0010507///negative regulation of autophagy+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0043087///regulation of GTPase activity+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0007165///signal transduction+++GO:0033625///positive regulation of integrin activation+++GO:1905709///negative regulation of membrane permeability+++GO:2000299///negative regulation of Rho-dependent protein serine/threonine kinase activity","Ras interacting protein 1","[RAIN_HUMAN|Reviewed]RecName: Full=Ras-interacting protein 1; Short=Rain;+++[M0R148_HUMAN|Unreviewed]SubName: Full=Ras-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000471633}; Flags: Fragment;+++[Q7L251_HUMAN|Unreviewed]SubName: Full=RASIP1 protein {ECO:0000313|EMBL:AAH21860.2}; Flags: Fragment;+++[Q8IUR2_HUMAN|Unreviewed]SubName: Full=RASIP1 protein {ECO:0000313|EMBL:AAH42111.1}; Flags: Fragment;"]
[54946,"'SLC41A3'",743,864,857,821.333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0008324///cation transmembrane transporter activity","GO:0006812///cation transport+++GO:0098655///cation transmembrane transport","solute carrier family 41 member 3","[S41A3_HUMAN|Reviewed]RecName: Full=Solute carrier family 41 member 3;+++[D3DNA7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41, member 3, isoform CRA_a {ECO:0000313|EMBL:EAW79377.1};+++[D6R925_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000422150}; Flags: Fragment;+++[D6R9M9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000423524}; Flags: Fragment;+++[D6R9S7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000423154}; Flags: Fragment;+++[D6R9X6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000422828}; Flags: Fragment;+++[D6RC02_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000422458}; Flags: Fragment;+++[D6RDB0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000425373}; Flags: Fragment;+++[D6RDM3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000425311};+++[D6RF72_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000424882}; Flags: Fragment;+++[D6RHE3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000421008}; Flags: Fragment;+++[D6RJC0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 41 member 3 {ECO:0000313|Ensembl:ENSP00000427254};"]
[54956,"'PARP16'",202.22,153,139.15,164.79,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0071782///endoplasmic reticulum tubular network+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0005515///protein binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0019900///kinase binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0016740///transferase activity","GO:0060548///negative regulation of cell death+++GO:0006471///protein ADP-ribosylation+++GO:0006986///response to unfolded protein+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0034356///NAD biosynthesis via nicotinamide riboside salvage pathway+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0070213///protein auto-ADP-ribosylation","poly(ADP-ribose) polymerase family member 16","[PAR16_HUMAN|Reviewed]RecName: Full=Mono [ADP-ribose] polymerase PARP16 {ECO:0000305}; EC=2.4.2.30 {ECO:0000269|PubMed:22701565}; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 15 {ECO:0000303|PubMed:20106667}; AltName: Full=Poly [ADP-ribose] polymerase 16; Short=PARP-16;+++[H3BV75_HUMAN|Unreviewed]SubName: Full=Mono [ADP-ribose] polymerase PARP16 {ECO:0000313|Ensembl:ENSP00000457982}; Flags: Fragment;"]
[5498,"'PPOX'",194,213,270,225.666666666667,"01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00860///Porphyrin and chlorophyll metabolism","H00202///Hepatic porphyria+++H01763///Porphyria","M00121///Heme biosynthesis, glutamate => heme","R03222///protoporphyrinogen-IX:oxygen oxidoreductase   Protoporphyrinogen IX + 3 Oxygen <=> Protoporphyrin + 3 Hydrogen peroxide+++R04178///coproporphyrinogen-III:oxygen oxidoreductase (coproporphyrin-forming)   Coproporphyrinogen III + 3 Oxygen <=> Coproporphyrin III + 3 Hydrogen peroxide","GO:0031305///integral component of mitochondrial inner membrane+++GO:0031966///mitochondrial membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0031304///intrinsic component of mitochondrial inner membrane","GO:0004729///oxygen-dependent protoporphyrinogen oxidase activity+++GO:0050660///flavin adenine dinucleotide binding","GO:0006779///porphyrin-containing compound biosynthetic process+++GO:0042493///response to drug+++GO:0055114///oxidation-reduction process+++GO:0006783///heme biosynthetic process+++GO:0006782///protoporphyrinogen IX biosynthetic process","protoporphyrinogen oxidase","[PPOX_HUMAN|Reviewed]RecName: Full=Protoporphyrinogen oxidase; Short=PPO; EC=1.3.3.4;+++[A0A1W2PNH4_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000490967};+++[A0A1W2PPA5_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000491230}; Flags: Fragment;+++[A0A1W2PQM0_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000491797};+++[A0A1W2PRF9_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000492580};+++[D3DVG2_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase, isoform CRA_d {ECO:0000313|EMBL:EAW52640.1};+++[F5GZT7_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000444216};+++[F5H1I5_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000439613};+++[F5H825_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000443769};+++[H0YFE1_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000438136}; Flags: Fragment;+++[H0YFP3_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|Ensembl:ENSP00000439544}; Flags: Fragment;+++[Q96RP0_HUMAN|Unreviewed]SubName: Full=Mutant protoporphyrinogen oxidase {ECO:0000313|EMBL:AAK69607.1}; Flags: Fragment;+++[Q96SE3_HUMAN|Unreviewed]SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|EMBL:AAK50375.1}; Flags: Fragment;+++[Q96TC9_HUMAN|Unreviewed]RecName: Full=Protoporphyrinogen oxidase {ECO:0000256|RuleBase:RU364052}; EC=1.3.3.4 {ECO:0000256|RuleBase:RU364052}; Flags: Fragment;"]
[54991,"'C1orf159'",308,351,346,335,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"chromosome 1 open reading frame 159","[CA159_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C1orf159; Flags: Precursor;+++[A0A024R082_HUMAN|Unreviewed]SubName: Full=Chromosome 1 open reading frame 159, isoform CRA_a {ECO:0000313|EMBL:EAW56290.1};+++[B2REC4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000416740}; Flags: Fragment;+++[B2REC5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000395935}; Flags: Fragment;+++[J3KSJ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000462517}; Flags: Fragment;+++[J3KT48_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000462798};+++[J3QKM1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000463144};+++[J3QRL0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000464273}; Flags: Fragment;+++[J3QSF0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000464657}; Flags: Fragment;+++[Q5T2W7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000390635}; Flags: Fragment;+++[Q5T2W9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C1orf159 {ECO:0000313|Ensembl:ENSP00000368624};"]
[55011,"'PIH1D1'",697,836,884,805.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0097255///R2TP complex+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0070761///pre-snoRNP complex","GO:0042393///histone binding+++GO:0051219///phosphoprotein binding+++GO:0005515///protein binding+++GO:0001165///RNA polymerase I upstream control element sequence-specific DNA binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0019901///protein kinase binding+++GO:0051117///ATPase binding","GO:0030855///epithelial cell differentiation+++GO:2001268///negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0048254///snoRNA localization+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0031334///positive regulation of protein complex assembly+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:0071169///establishment of protein localization to chromatin+++GO:1901838///positive regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1904263///positive regulation of TORC1 signaling+++GO:0006364///rRNA processing+++GO:0006338///chromatin remodeling+++GO:0000492///box C/D snoRNP assembly+++GO:0051569///regulation of histone H3-K4 methylation+++GO:1900110///negative regulation of histone H3-K9 dimethylation+++GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:1903939///regulation of TORC2 signaling+++GO:1900113///negative regulation of histone H3-K9 trimethylation+++GO:1902661///positive regulation of glucose mediated signaling pathway+++GO:2000619///negative regulation of histone H4-K16 acetylation+++GO:0090240///positive regulation of histone H4 acetylation","PIH1 domain containing 1","[PIHD1_HUMAN|Reviewed]RecName: Full=PIH1 domain-containing protein 1; AltName: Full=Nucleolar protein 17 homolog;+++[M0QXD5_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469087}; Flags: Fragment;+++[M0QYA2_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469693}; Flags: Fragment;+++[M0QYF4_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469793}; Flags: Fragment;+++[M0QZ61_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000470322}; Flags: Fragment;+++[M0QZM3_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000470639}; Flags: Fragment;+++[M0QZZ1_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000470875}; Flags: Fragment;+++[M0R028_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000470947}; Flags: Fragment;+++[M0R0J2_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000471275}; Flags: Fragment;+++[M0R1R3_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472065}; Flags: Fragment;+++[M0R2H3_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472571}; Flags: Fragment;+++[M0R2P8_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472715}; Flags: Fragment;+++[M0R3A4_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000473095}; Flags: Fragment;+++[M0R3A8_HUMAN|Unreviewed]SubName: Full=PIH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000473100}; Flags: Fragment;"]
[55024,"'BANK1'",13,15,10,12.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane","GO:0005102///signaling receptor binding+++GO:1990782///protein tyrosine kinase binding","GO:0009617///response to bacterium+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0045947///negative regulation of translational initiation+++GO:1900165///negative regulation of interleukin-6 secretion+++GO:0050869///negative regulation of B cell activation+++GO:0042113///B cell activation","B cell scaffold protein with ankyrin repeats 1","[BANK1_HUMAN|Reviewed]RecName: Full=B-cell scaffold protein with ankyrin repeats;"]
[55052,"'MRPL20'",577,583,702,620.666666666667,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005762///mitochondrial large ribosomal subunit+++GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005761///mitochondrial ribosome+++GO:0005743///mitochondrial inner membrane","GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:0000027///ribosomal large subunit assembly+++GO:0006412///translation","mitochondrial ribosomal protein L20","[RM20_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L20, mitochondrial; Short=L20mt; Short=MRP-L20; AltName: Full=Mitochondrial large ribosomal subunit protein bL20m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[I3L2X1_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L20, mitochondrial {ECO:0000313|Ensembl:ENSP00000459994}; Flags: Fragment;"]
[55069,"'TMEM248'",1972,2197,1928,2032.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"transmembrane protein 248","[TM248_HUMAN|Reviewed]RecName: Full=Transmembrane protein 248;+++[A0A024RDK7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX07908.1};+++[C9J3C8_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 248 {ECO:0000313|Ensembl:ENSP00000410505}; Flags: Fragment;+++[C9JKP5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 248 {ECO:0000313|Ensembl:ENSP00000413824}; Flags: Fragment;+++[F8WE75_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 248 {ECO:0000313|Ensembl:ENSP00000394507}; Flags: Fragment;+++[U3KQ21_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 248 {ECO:0000313|Ensembl:ENSP00000475466}; Flags: Fragment;"]
[55093,"'WDYHV1'",29,39,42,36.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,null,"R11560///protein N-terminal glutamine amidohydrolase   L-Glutaminyl-peptide + H2O <=> L-Glutamyl-protein + Ammonia","GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0070773///protein-N-terminal glutamine amidohydrolase activity+++GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides","GO:0006464///cellular protein modification process","WDYHV motif containing 1","[NTAQ1_HUMAN|Reviewed]RecName: Full=Protein N-terminal glutamine amidohydrolase; EC=3.5.1.122 {ECO:0000250|UniProtKB:Q80WB5}; AltName: Full=Protein NH2-terminal glutamine deamidase; Short=N-terminal Gln amidase; Short=Nt(Q)-amidase; AltName: Full=WDYHV motif-containing protein 1;+++[A0A024R9I8_HUMAN|Unreviewed]SubName: Full=Chromosome 8 open reading frame 32, isoform CRA_a {ECO:0000313|EMBL:EAW92039.1};+++[E5RHC2_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000428615};+++[E5RIY9_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000429258};+++[E9PRB7_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000434252}; Flags: Fragment;+++[H0YBV4_HUMAN|Unreviewed]SubName: Full=Protein N-terminal glutamine amidohydrolase {ECO:0000313|Ensembl:ENSP00000430390}; Flags: Fragment;"]
[5511,"'PPP1R8'",527,613,544,561.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0003677///DNA binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0019888///protein phosphatase regulator activity+++GO:0004865///protein serine/threonine phosphatase inhibitor activity+++GO:0004518///nuclease activity+++GO:0005515///protein binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0004519///endonuclease activity+++GO:0008995///ribonuclease E activity+++GO:0003729///mRNA binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0008380///RNA splicing+++GO:0035308///negative regulation of protein dephosphorylation+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0008283///cell proliferation+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0006401///RNA catabolic process+++GO:0006397///mRNA processing","protein phosphatase 1 regulatory subunit 8","[PP1R8_HUMAN|Reviewed]RecName: Full=Nuclear inhibitor of protein phosphatase 1; Short=NIPP-1; AltName: Full=Protein phosphatase 1 regulatory inhibitor subunit 8; Includes: RecName: Full=Activator of RNA decay; EC=3.1.4.-; AltName: Full=ARD-1;+++[A0A0A0MT09_HUMAN|Unreviewed]SubName: Full=Nuclear inhibitor of protein phosphatase 1 {ECO:0000313|Ensembl:ENSP00000410206}; Flags: Fragment;+++[Q38J66_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1 regulatory subunit 8 testis splice variant {ECO:0000313|EMBL:ABB04281.1}; Flags: Fragment;+++[Q561W4_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1, regulatory (Inhibitor) subunit 8 {ECO:0000313|EMBL:AAH93017.1};+++[Q6ICT4_HUMAN|Unreviewed]SubName: Full=PPP1R8 protein {ECO:0000313|EMBL:CAG29305.1}; SubName: Full=Protein phosphatase 1, regulatory (Inhibitor) subunit 8, isoform CRA_f {ECO:0000313|EMBL:EAX07736.1}; SubName: Full=cDNA FLJ60722, highly similar to Nuclear inhibitor of protein phosphatase 1 {ECO:0000313|EMBL:BAG60117.1}; SubName: Full=cDNA, FLJ94432, Homo sapiens protein phosphatase 1, regulatory (inhibitor) subunit8 (PPP1R8), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG36550.1}; Flags: Fragment;"]
[55130,"'ARMC4'",32,31,26,29.6666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0097546///ciliary base+++GO:0005737///cytoplasm+++GO:0005930///axoneme+++GO:0005929///cilium+++GO:0042995///cell projection",null,"GO:0036158///outer dynein arm assembly+++GO:0007368///determination of left/right symmetry+++GO:0030030///cell projection organization+++GO:0021591///ventricular system development+++GO:0007507///heart development+++GO:0003341///cilium movement+++GO:0003356///regulation of cilium beat frequency","armadillo repeat containing 4","[ARMC4_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing protein 4;+++[A0A140VKF7_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 74n {ECO:0000313|EMBL:AEE61294.1};+++[B7Z7A1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52288, highly similar to Armadillo repeat-containing protein 4 {ECO:0000313|EMBL:BAH13537.1};+++[B7Z7Y0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52368, highly similar to Armadillo repeat-containing protein 4 {ECO:0000313|EMBL:BAH13766.1};+++[Q5T2S9_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 4 {ECO:0000313|Ensembl:ENSP00000398155}; Flags: Fragment;+++[R4GN11_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 4 {ECO:0000313|Ensembl:ENSP00000473438}; Flags: Fragment;"]
[55148,"'UBR7'",320,291,308,306.333333333333,{"$nulls":5},"GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003674///molecular_function+++GO:0061630///ubiquitin protein ligase activity","GO:0016567///protein ubiquitination+++GO:0008150///biological_process","ubiquitin protein ligase E3 component n-recognin 7 (putative)","[UBR7_HUMAN|Reviewed]RecName: Full=Putative E3 ubiquitin-protein ligase UBR7; EC=2.3.2.27; AltName: Full=N-recognin-7; AltName: Full=RING-type E3 ubiquitin transferase UBR7;+++[E9PCJ7_HUMAN|Unreviewed]SubName: Full=Putative E3 ubiquitin-protein ligase UBR7 {ECO:0000313|Ensembl:ENSP00000479570};+++[G3V253_HUMAN|Unreviewed]SubName: Full=Putative E3 ubiquitin-protein ligase UBR7 {ECO:0000313|Ensembl:ENSP00000450470};+++[G3V2G3_HUMAN|Unreviewed]SubName: Full=Putative E3 ubiquitin-protein ligase UBR7 {ECO:0000313|Ensembl:ENSP00000450645}; Flags: Fragment;+++[G3V336_HUMAN|Unreviewed]SubName: Full=Putative E3 ubiquitin-protein ligase UBR7 {ECO:0000313|Ensembl:ENSP00000451022}; Flags: Fragment;+++[H0YJA0_HUMAN|Unreviewed]SubName: Full=Putative E3 ubiquitin-protein ligase UBR7 {ECO:0000313|Ensembl:ENSP00000451051}; Flags: Fragment;+++[H0YJM2_HUMAN|Unreviewed]SubName: Full=Putative E3 ubiquitin-protein ligase UBR7 {ECO:0000313|Ensembl:ENSP00000451785}; Flags: Fragment;+++[H0YJY4_HUMAN|Unreviewed]SubName: Full=Putative E3 ubiquitin-protein ligase UBR7 {ECO:0000313|Ensembl:ENSP00000452488}; Flags: Fragment;+++[L8E9R4_HUMAN|Unreviewed]SubName: Full=Alternative protein UBR7 {ECO:0000313|EMBL:CCQ43904.1};+++[Q05DA8_HUMAN|Unreviewed]SubName: Full=UBR7 protein {ECO:0000313|EMBL:AAH17013.1};"]
[55165,"'CEP55'",2,6,7,5,null,"H01937///Multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly (MARCH)",null,null,"GO:0016020///membrane+++GO:0005814///centriole+++GO:0032154///cleavage furrow+++GO:0090543///Flemming body+++GO:0045171///intercellular bridge+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome","GO:0005515///protein binding","GO:0072001///renal system development+++GO:1904888///cranial skeletal system development+++GO:0000920///septum digestion after cytokinesis+++GO:0045184///establishment of protein localization+++GO:0061952///midbody abscission+++GO:0007275///multicellular organism development+++GO:0000281///mitotic cytokinesis+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0051301///cell division+++GO:0006997///nucleus organization+++GO:0007080///mitotic metaphase plate congression+++GO:0007049///cell cycle","centrosomal protein 55","[CEP55_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 55 kDa {ECO:0000312|HGNC:HGNC:1161}; Short=Cep55; AltName: Full=Up-regulated in colon cancer 6;+++[H0Y432_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 55 kDa {ECO:0000313|Ensembl:ENSP00000389150}; Flags: Fragment;"]
[55182,"'RNF220'",728,793,768,763,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:0016567///protein ubiquitination+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0051865///protein autoubiquitination","ring finger protein 220","[RN220_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF220; EC=2.3.2.27; AltName: Full=RING finger protein 220; AltName: Full=RING-type E3 ubiquitin transferase RNF220 {ECO:0000305};+++[H0Y7B1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF220 {ECO:0000313|Ensembl:ENSP00000411541}; Flags: Fragment;+++[Q5TDE7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF220 {ECO:0000313|Ensembl:ENSP00000388533}; Flags: Fragment;+++[Q5TDE8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF220 {ECO:0000313|Ensembl:ENSP00000335580}; Flags: Fragment;+++[Q9BWG1_HUMAN|Unreviewed]SubName: Full=RNF220 protein {ECO:0000313|EMBL:AAH00279.1};+++[U3KPZ6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF220 {ECO:0000313|Ensembl:ENSP00000475383};"]
[55198,"'APPL2'",566.12,498,430,498.04,{"$nulls":4},"GO:0031901///early endosome membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0010008///endosome membrane","GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0006310///DNA recombination+++GO:0007049///cell cycle+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated","adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2","[DP13B_HUMAN|Reviewed]RecName: Full=DCC-interacting protein 13-beta; Short=Dip13-beta; AltName: Full=Adapter protein containing PH domain, PTB domain and leucine zipper motif 2;+++[F8VR68_HUMAN|Unreviewed]SubName: Full=DCC-interacting protein 13-beta {ECO:0000313|Ensembl:ENSP00000448569};+++[F8VS86_HUMAN|Unreviewed]SubName: Full=DCC-interacting protein 13-beta {ECO:0000313|Ensembl:ENSP00000447828};+++[F8VWV2_HUMAN|Unreviewed]SubName: Full=DCC-interacting protein 13-beta {ECO:0000313|Ensembl:ENSP00000449767}; Flags: Fragment;+++[F8VXB0_HUMAN|Unreviewed]SubName: Full=DCC-interacting protein 13-beta {ECO:0000313|Ensembl:ENSP00000449410};+++[F8W124_HUMAN|Unreviewed]SubName: Full=DCC-interacting protein 13-beta {ECO:0000313|Ensembl:ENSP00000447520}; Flags: Fragment;+++[H0YH86_HUMAN|Unreviewed]SubName: Full=DCC-interacting protein 13-beta {ECO:0000313|Ensembl:ENSP00000446510}; Flags: Fragment;"]
[552,"'AVPR1A'",3,1,0,1.33333333333333,"04072///Phospholipase D signaling pathway+++04020///Calcium signaling pathway+++04270///Vascular smooth muscle contraction+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005768///endosome+++GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0031894///V1A vasopressin receptor binding+++GO:0005515///protein binding+++GO:0005080///protein kinase C binding+++GO:0017046///peptide hormone binding+++GO:0005000///vasopressin receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007165///signal transduction+++GO:0010035///response to inorganic substance+++GO:0007621///negative regulation of female receptivity+++GO:0019722///calcium-mediated signaling+++GO:0035176///social behavior+++GO:0043084///penile erection+++GO:0045777///positive regulation of blood pressure+++GO:0032870///cellular response to hormone stimulus+++GO:0042631///cellular response to water deprivation+++GO:0051412///response to corticosterone+++GO:0010033///response to organic substance+++GO:0014902///myotube differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0021537///telencephalon development+++GO:0035815///positive regulation of renal sodium excretion+++GO:0006091///generation of precursor metabolites and energy+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032849///positive regulation of cellular pH reduction+++GO:0014049///positive regulation of glutamate secretion+++GO:0042711///maternal behavior+++GO:0010460///positive regulation of heart rate+++GO:0007625///grooming behavior+++GO:0031394///positive regulation of prostaglandin biosynthetic process+++GO:0008015///blood circulation+++GO:0045907///positive regulation of vasoconstriction+++GO:0002125///maternal aggressive behavior+++GO:0051970///negative regulation of transmission of nerve impulse+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0042713///sperm ejaculation+++GO:0001992///regulation of systemic arterial blood pressure by vasopressin+++GO:0007202///activation of phospholipase C activity+++GO:0030307///positive regulation of cell growth","arginine vasopressin receptor 1A","[V1AR_HUMAN|Reviewed]RecName: Full=Vasopressin V1a receptor; Short=V1aR; AltName: Full=AVPR V1a; AltName: Full=Antidiuretic hormone receptor 1a; AltName: Full=Vascular/hepatic-type arginine vasopressin receptor;+++[F8VW98_HUMAN|Unreviewed]RecName: Full=Vasopressin V1a receptor {ECO:0000256|RuleBase:RU046427};+++[Q3S2J4_HUMAN|Unreviewed]RecName: Full=Vasopressin V1a receptor {ECO:0000256|RuleBase:RU046427};+++[X5D2B0_HUMAN|Unreviewed]RecName: Full=Vasopressin V1a receptor {ECO:0000256|RuleBase:RU046427}; Flags: Fragment;+++[X5D789_HUMAN|Unreviewed]RecName: Full=Vasopressin V1a receptor {ECO:0000256|RuleBase:RU046427}; Flags: Fragment;"]
[55229,"'PANK4'",409,393,378,393.333333333333,"01100///Metabolic pathways+++00770///Pantothenate and CoA biosynthesis","H00832///Core neuroacanthocytosis syndromes+++H00833///Neurodegeneration with brain iron accumulation (NBIA)","M00120///Coenzyme A biosynthesis, pantothenate => CoA","R02971///ATP:pantothenate 4'-phosphotransferase   ATP + Pantetheine <=> ADP + Pantetheine 4'-phosphate+++R03018///ATP:pantothenate 4'-phosphotransferase   ATP + Pantothenate <=> ADP + D-4'-Phosphopantothenate+++R04391///ATP:pantothenate 4'-phosphotransferase   ATP + N-((R)-Pantothenoyl)-L-cysteine <=> ADP + (R)-4'-Phosphopantothenoyl-L-cysteine","GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0004594///pantothenate kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity","GO:0015937///coenzyme A biosynthetic process+++GO:0016310///phosphorylation","pantothenate kinase 4","[PANK4_HUMAN|Reviewed]RecName: Full=Pantothenate kinase 4; Short=hPanK4; EC=2.7.1.33; AltName: Full=Pantothenic acid kinase 4;+++[A0A0G2JQS7_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 {ECO:0000313|Ensembl:ENSP00000486126};+++[A0A0G2JR38_HUMAN|Unreviewed]RecName: Full=Pantothenate kinase 4 {ECO:0000256|PIRNR:PIRNR036939}; EC=2.7.1.33 {ECO:0000256|PIRNR:PIRNR036939};+++[D6RJF3_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 {ECO:0000313|Ensembl:ENSP00000425674}; Flags: Fragment;+++[E9PHT6_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 {ECO:0000313|Ensembl:ENSP00000421433}; Flags: Fragment;+++[H0Y9E4_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 {ECO:0000313|Ensembl:ENSP00000423920}; Flags: Fragment;+++[H0YA02_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 {ECO:0000313|Ensembl:ENSP00000425668}; Flags: Fragment;+++[H0YA26_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 {ECO:0000313|Ensembl:ENSP00000425932}; Flags: Fragment;+++[H0YA31_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 {ECO:0000313|Ensembl:ENSP00000425977}; Flags: Fragment;+++[Q7RTX2_HUMAN|Unreviewed]SubName: Full=Pantothenate kinase 4 putative variant {ECO:0000313|EMBL:DAA00007.1}; SubName: Full=Pantothenate kinase 4, isoform CRA_b {ECO:0000313|EMBL:EAW56098.1};"]
[55231,"'CCDC87'",19,30,43,30.6666666666667,{"$nulls":5},"GO:0005515///protein binding","GO:1905516///positive regulation of fertilization+++GO:0007338///single fertilization+++GO:0007283///spermatogenesis+++GO:0030154///cell differentiation+++GO:2000344///positive regulation of acrosome reaction","coiled-coil domain containing 87","[CCD87_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 87;"]
[55252,"'ASXL2'",778,919,437,711.333333333333,null,"H01481///Myelodysplastic syndrome (MDS)+++H02047///Bohring-Opitz syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0035517///PR-DUB complex","GO:0003682///chromatin binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0016579///protein deubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0009887///animal organ morphogenesis+++GO:0006351///transcription, DNA-templated","ASXL transcriptional regulator 2","[ASXL2_HUMAN|Reviewed]RecName: Full=Putative Polycomb group protein ASXL2; AltName: Full=Additional sex combs-like protein 2;+++[E7EWD6_HUMAN|Unreviewed]SubName: Full=Putative Polycomb group protein ASXL2 {ECO:0000313|Ensembl:ENSP00000337250};"]
[55268,"'ECHDC2'",376,351,354,360.333333333333,"00120///Primary bile acid biosynthesis+++01100///Metabolic pathways+++03320///PPAR signaling pathway+++04146///Peroxisome","H00407///Peroxisomal beta-oxidation enzyme deficiency+++H00874///Leukoencephalopathy with dystonia and motor neuropathy","M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R03719///3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase; choloyl-CoA:propanoyl-CoA Propanoyl-CoA + Choloyl-CoA <=> CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA+++R04811///Propanoyl-CoA:acetyl-CoA C-acyltransferase; 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA; C-acyltransferase Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA","GO:0005739///mitochondrion","GO:0016829///lyase activity+++GO:0004300///enoyl-CoA hydratase activity+++GO:0003824///catalytic activity","GO:0006635///fatty acid beta-oxidation+++GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process","enoyl-CoA hydratase domain containing 2","[ECHD2_HUMAN|Reviewed]RecName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial; Flags: Precursor;+++[F5GWU3_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000441962}; Flags: Fragment;+++[F5H0R2_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000360575};+++[F5H2K9_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000446190};+++[F5H408_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000438535};+++[F5H4W3_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000439906};+++[F6RJU0_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA hydratase domain-containing protein 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000439264};+++[Q86V13_HUMAN|Unreviewed]SubName: Full=ECHDC2 protein {ECO:0000313|EMBL:AAH51887.1}; Flags: Fragment;"]
[55287,"'TMEM40'",4,0,0,1.33333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","transmembrane protein 40","[TMM40_HUMAN|Reviewed]RecName: Full=Transmembrane protein 40;+++[B4DXI0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55821, highly similar to Homo sapiens transmembrane protein 40 (TMEM40), mRNA {ECO:0000313|EMBL:BAG63392.1};+++[H7BZY7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 40 {ECO:0000313|Ensembl:ENSP00000392140}; Flags: Fragment;"]
[55296,"'TBC1D19'",351,296,217,288,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:1902017///regulation of cilium assembly","TBC1 domain family member 19","[TBC19_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 19;+++[D6RA60_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 19 {ECO:0000313|Ensembl:ENSP00000423116}; Flags: Fragment;+++[D6RA74_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 19 {ECO:0000313|Ensembl:ENSP00000423097}; Flags: Fragment;+++[D6RD52_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 19 {ECO:0000313|Ensembl:ENSP00000427033}; Flags: Fragment;+++[D6RDZ1_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 19 {ECO:0000313|Ensembl:ENSP00000425176}; Flags: Fragment;"]
[55321,"'TMEM74B'",8,12,9,9.66666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 74B","[TM74B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 74B;+++[Q5QPM3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 74B {ECO:0000313|Ensembl:ENSP00000400552}; Flags: Fragment;"]
[55330,"'BLOC1S4'",152,138,165,151.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:1904115///axon cytoplasm+++GO:0005737///cytoplasm+++GO:0031083///BLOC-1 complex","GO:0005515///protein binding","GO:0008089///anterograde axonal transport+++GO:0050885///neuromuscular process controlling balance+++GO:0070527///platelet aggregation+++GO:0031175///neuron projection development+++GO:0032438///melanosome organization+++GO:0048490///anterograde synaptic vesicle transport","biogenesis of lysosomal organelles complex 1 subunit 4","[BL1S4_HUMAN|Reviewed]RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 4; Short=BLOC-1 subunit 4; AltName: Full=Protein cappuccino homolog;"]
[55357,"'TBC1D2'",4803,6180,5762,5581.66666666667,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030054///cell junction","GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:1902017///regulation of cilium assembly","TBC1 domain family member 2","[TBD2A_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 2A; AltName: Full=Armus; AltName: Full=Prostate antigen recognized and identified by SEREX 1; Short=PARIS-1;+++[A0A024R166_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 2, isoform CRA_f {ECO:0000313|EMBL:EAW58888.1};"]
[5537,"'PPP6C'",534,451,509,498,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0000139///Golgi membrane+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity","GO:0000082///G1/S transition of mitotic cell cycle+++GO:0002376///immune system process+++GO:0006470///protein dephosphorylation+++GO:0007049///cell cycle+++GO:0048208///COPII vesicle coating+++GO:0045087///innate immune response","protein phosphatase 6 catalytic subunit","[PPP6_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit; Short=PP6C; EC=3.1.3.16; Contains: RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed;+++[A0A024R861_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[A0A0S2Z482_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 6 catalytic subunit isoform 2 {ECO:0000313|EMBL:ALQ33730.1};+++[Q5T1S7_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;"]
[55486,"'PARL'",202,199,273,224.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane","GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004175///endopeptidase activity+++GO:0008236///serine-type peptidase activity","GO:0030162///regulation of proteolysis+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0033619///membrane protein proteolysis+++GO:0006508///proteolysis+++GO:0010821///regulation of mitochondrion organization","presenilin associated rhomboid like","[PARL_HUMAN|Reviewed]RecName: Full=Presenilins-associated rhomboid-like protein, mitochondrial; EC=3.4.21.105; AltName: Full=Mitochondrial intramembrane cleaving protease PARL; Contains: RecName: Full=P-beta; Short=Pbeta; Flags: Precursor;+++[A0A1W2PP66_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000491186};+++[A0A1W2PS40_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000492596};+++[C9JNP8_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000402137};+++[F8WCQ4_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000404421};+++[H7C045_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000392926}; Flags: Fragment;+++[H7C0U0_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000396691}; Flags: Fragment;+++[H7C122_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000398043}; Flags: Fragment;+++[H7C1V6_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000402689}; Flags: Fragment;"]
[55506,"'H2AFY2'",704,659,724,695.666666666667,"05034///Alcoholism+++04217///Necroptosis+++05322///Systemic lupus erythematosus",{"$nulls":3},"GO:0000786///nucleosome+++GO:0000790///nuclear chromatin+++GO:0005694///chromosome+++GO:0001740///Barr body+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0000785///chromatin+++GO:0005634///nucleus","GO:0044212///transcription regulatory region DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0031490///chromatin DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding","GO:0006325///chromatin organization+++GO:0007549///dosage compensation+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:0007420///brain development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0071169///establishment of protein localization to chromatin+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0006334///nucleosome assembly+++GO:0045618///positive regulation of keratinocyte differentiation","H2A histone family member Y2","[H2AW_HUMAN|Reviewed]RecName: Full=Core histone macro-H2A.2; Short=Histone macroH2A2; Short=mH2A2;+++[A0A024QZP6_HUMAN|Unreviewed]RecName: Full=Core histone macro-H2A {ECO:0000256|PIRNR:PIRNR037942};+++[Q5SQT3_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767}; Flags: Fragment;"]
[55561,"'CDC42BPG'",77,111,93,93.6666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0031252///cell leading edge+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center","GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding","GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0031532///actin cytoskeleton reorganization+++GO:0006468///protein phosphorylation","CDC42 binding protein kinase gamma","[MRCKG_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase MRCK gamma; EC=2.7.11.1; AltName: Full=CDC42-binding protein kinase gamma; AltName: Full=DMPK-like gamma; AltName: Full=Myotonic dystrophy kinase-related CDC42-binding kinase gamma; Short=MRCK gamma; Short=MRCKG; Short=Myotonic dystrophy protein kinase-like gamma; AltName: Full=Myotonic dystrophy protein kinase-like alpha;"]
[55573,"'CDV3'",3538,3575,3302,3471.66666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0003674///molecular_function","GO:0008283///cell proliferation","CDV3 homolog","[CDV3_HUMAN|Reviewed]RecName: Full=Protein CDV3 homolog;+++[D3DND1_HUMAN|Unreviewed]SubName: Full=CDV3 homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW79177.1};+++[D6R973_HUMAN|Unreviewed]SubName: Full=Protein CDV3 homolog {ECO:0000313|Ensembl:ENSP00000423349}; Flags: Fragment;+++[D6R9V8_HUMAN|Unreviewed]SubName: Full=Protein CDV3 homolog {ECO:0000313|Ensembl:ENSP00000422866};+++[D6RAV0_HUMAN|Unreviewed]SubName: Full=Protein CDV3 homolog {ECO:0000313|Ensembl:ENSP00000424742}; Flags: Fragment;+++[D6RDN0_HUMAN|Unreviewed]SubName: Full=Protein CDV3 homolog {ECO:0000313|Ensembl:ENSP00000425297};+++[D6RFH2_HUMAN|Unreviewed]SubName: Full=Protein CDV3 homolog {ECO:0000313|Ensembl:ENSP00000421495};+++[H0Y8K3_HUMAN|Unreviewed]SubName: Full=Protein CDV3 homolog {ECO:0000313|Ensembl:ENSP00000421340}; Flags: Fragment;"]
[55615,"'PRR5'",689,618,629,645.333333333333,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0031932///TORC2 complex+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0032148///activation of protein kinase B activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0038203///TORC2 signaling+++GO:0007049///cell cycle","proline rich 5","[PRR5_HUMAN|Reviewed]RecName: Full=Proline-rich protein 5; AltName: Full=Protein observed with Rictor-1; Short=Protor-1;+++[A0A024R4U5_HUMAN|Unreviewed]SubName: Full=HCG2039433, isoform CRA_h {ECO:0000313|EMBL:EAW73357.1};+++[A8K699_HUMAN|Unreviewed]SubName: Full=HCG2039433, isoform CRA_i {ECO:0000313|EMBL:EAW73354.1}; SubName: Full=cDNA FLJ77560, highly similar to Homo sapiens proline rich protein 5 (PRR5), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84253.1};+++[B1AHG3_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 5 {ECO:0000313|Ensembl:ENSP00000410215}; Flags: Fragment;+++[B1AHG4_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 5 {ECO:0000313|Ensembl:ENSP00000400925}; Flags: Fragment;+++[E9PH80_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 5 {ECO:0000313|Ensembl:ENSP00000384746}; Flags: Fragment;+++[F8WEZ7_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 5 {ECO:0000313|Ensembl:ENSP00000407637};+++[G3V0G2_HUMAN|Unreviewed]SubName: Full=HCG2039433, isoform CRA_a {ECO:0000313|EMBL:EAW73346.1}; SubName: Full=Proline-rich protein 5 {ECO:0000313|Ensembl:ENSP00000392026};"]
[55620,"'STAP2'",184,189,245,206,"04140///Autophagy - animal+++04144///Endocytosis+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0035591///signaling adaptor activity","GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0009967///positive regulation of signal transduction","signal transducing adaptor family member 2","[STAP2_HUMAN|Reviewed]RecName: Full=Signal-transducing adaptor protein 2; Short=STAP-2; AltName: Full=Breast tumor kinase substrate; Short=BRK substrate;+++[M0QY82_HUMAN|Unreviewed]SubName: Full=Signal-transducing adaptor protein 2 {ECO:0000313|Ensembl:ENSP00000469657}; Flags: Fragment;+++[M0QZ60_HUMAN|Unreviewed]SubName: Full=Signal-transducing adaptor protein 2 {ECO:0000313|Ensembl:ENSP00000470321};+++[M0R0J5_HUMAN|Unreviewed]SubName: Full=Signal-transducing adaptor protein 2 {ECO:0000313|Ensembl:ENSP00000471281}; Flags: Fragment;+++[M0R2W4_HUMAN|Unreviewed]SubName: Full=Signal-transducing adaptor protein 2 {ECO:0000313|Ensembl:ENSP00000472851}; Flags: Fragment;"]
[55631,"'LRRC40'",81,115,122,106,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane",null,"GO:0007165///signal transduction","leucine rich repeat containing 40","[LRC40_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 40;+++[A0A140VJN3_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat containing 40 {ECO:0000313|EMBL:EAX06460.1}; SubName: Full=Testicular tissue protein Li 109 {ECO:0000313|EMBL:AEE61020.1};"]
[55656,"'INTS8'",317,285.01,286,296.003333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0016180///snRNA processing+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0034472///snRNA 3'-end processing","integrator complex subunit 8","[INT8_HUMAN|Reviewed]RecName: Full=Integrator complex subunit 8; Short=Int8; AltName: Full=Protein kaonashi-1;+++[E5RG48_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000427840};+++[E5RH10_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430033}; Flags: Fragment;+++[E5RIN8_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000429340}; Flags: Fragment;+++[E5RJF0_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000428260}; Flags: Fragment;+++[E5RJL5_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000429056}; Flags: Fragment;+++[H0YBQ1_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430049}; Flags: Fragment;+++[H0YBS1_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430180}; Flags: Fragment;+++[H0YC12_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000430722}; Flags: Fragment;+++[J3KNV5_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 8 {ECO:0000313|Ensembl:ENSP00000343274};"]
[55668,"'GPATCH2L'",1062,851,586,833,{"$nulls":5},"GO:0005515///protein binding",null,"G-patch domain containing 2 like","[GPT2L_HUMAN|Reviewed]RecName: Full=G patch domain-containing protein 2-like;+++[A0A024R6E4_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 118, isoform CRA_d {ECO:0000313|EMBL:EAW81256.1};+++[A0A024R6J0_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 118, isoform CRA_b {ECO:0000313|EMBL:EAW81255.1};+++[G3V290_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 2-like {ECO:0000313|Ensembl:ENSP00000450521}; Flags: Fragment;+++[G3V3M4_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 2-like {ECO:0000313|Ensembl:ENSP00000451325}; Flags: Fragment;+++[G3V4I8_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 2-like {ECO:0000313|Ensembl:ENSP00000451827}; Flags: Fragment;+++[G3V4L1_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 2-like {ECO:0000313|Ensembl:ENSP00000451868};+++[G3V553_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 2-like {ECO:0000313|Ensembl:ENSP00000452180};+++[G3V5D0_HUMAN|Unreviewed]SubName: Full=G patch domain-containing protein 2-like {ECO:0000313|Ensembl:ENSP00000452294}; Flags: Fragment;"]
[55692,"'LUC7L'",339,428,402,389.666666666667,"05143///African trypanosomiasis+++05144///Malaria","H00228///Thalassemia",null,null,"GO:0071004///U2-type prespliceosome+++GO:0005685///U1 snRNP","GO:0050733///RS domain binding+++GO:0003729///mRNA binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0006376///mRNA splice site selection+++GO:0045843///negative regulation of striated muscle tissue development","LUC7 like","[LUC7L_HUMAN|Reviewed]RecName: Full=Putative RNA-binding protein Luc7-like 1; AltName: Full=Putative SR protein LUC7B1; AltName: Full=SR+89;+++[A8MYV2_HUMAN|Unreviewed]SubName: Full=LUC7-like (S. cerevisiae), isoform CRA_f {ECO:0000313|EMBL:EAW85858.1}; SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000380882};+++[B8ZZ08_HUMAN|Unreviewed]SubName: Full=LUC7-like (S. cerevisiae) {ECO:0000313|EMBL:CAM26669.1}; SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000413033}; Flags: Fragment;+++[B8ZZ09_HUMAN|Unreviewed]SubName: Full=LUC7-like (S. cerevisiae) {ECO:0000313|EMBL:CAX15222.1}; SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000414508}; Flags: Fragment;+++[B8ZZ10_HUMAN|Unreviewed]SubName: Full=LUC7-like (S. cerevisiae) {ECO:0000313|EMBL:CAX15223.1}; SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000406695}; Flags: Fragment;+++[B8ZZ12_HUMAN|Unreviewed]SubName: Full=LUC7-like (S. cerevisiae) {ECO:0000313|EMBL:CAX15224.1}; SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000409977}; Flags: Fragment;+++[D3DU41_HUMAN|Unreviewed]SubName: Full=LUC7-like (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW85851.1};+++[F2Z322_HUMAN|Unreviewed]SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000414860};+++[F8WBC1_HUMAN|Unreviewed]SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000390953};+++[H7C2U4_HUMAN|Unreviewed]SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|Ensembl:ENSP00000407781}; Flags: Fragment;+++[Q1W6G4_HUMAN|Unreviewed]SubName: Full=LUC7-like (S. cerevisiae) {ECO:0000313|EMBL:CAM26672.1}; SubName: Full=LUC7-like (S. cerevisiae), isoform CRA_g {ECO:0000313|EMBL:EAW85859.1}; SubName: Full=Putative RNA-binding protein Luc7-like 1 {ECO:0000313|EMBL:ABD95913.1};"]
[55706,"'NDC1'",330,314,252,298.666666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0031965///nuclear membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016021///integral component of membrane+++GO:0015629///actin cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0070762///nuclear pore transmembrane ring+++GO:0005643///nuclear pore","GO:0017056///structural constituent of nuclear pore","GO:0006406///mRNA export from nucleus+++GO:0051028///mRNA transport+++GO:0007283///spermatogenesis+++GO:0016032///viral process+++GO:0007129///synapsis+++GO:0031081///nuclear pore distribution+++GO:0051292///nuclear pore complex assembly+++GO:0015031///protein transport+++GO:0006999///nuclear pore organization","NDC1 transmembrane nucleoporin","[NDC1_HUMAN|Reviewed]RecName: Full=Nucleoporin NDC1; Short=hNDC1; AltName: Full=Transmembrane protein 48;"]
[55729,"'ATF7IP'",1321,1285.75,1071.52,1226.09,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0016887///ATPase activity","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0016032///viral process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045898///regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0006306///DNA methylation","activating transcription factor 7 interacting protein","[MCAF1_HUMAN|Reviewed]RecName: Full=Activating transcription factor 7-interacting protein 1; AltName: Full=ATF-interacting protein; Short=ATF-IP; AltName: Full=ATF7-interacting protein; AltName: Full=ATFa-associated modulator; Short=hAM; AltName: Full=MBD1-containing chromatin-associated factor 1; AltName: Full=P621;+++[A0A024RAY1_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7 interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAW96315.1};+++[A8MV73_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000379575}; Flags: Fragment;+++[B3KNI7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14669 fis, clone NT2RP2003243, highly similar to Homo sapiens activating transcription factor 7 interacting protein (ATF7IP), mRNA {ECO:0000313|EMBL:BAG51349.1};+++[B3KQF8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90387 fis, clone NT2RP2005391, highly similar to Homo sapiens activating transcription factor 7 interacting protein (ATF7IP), mRNA {ECO:0000313|EMBL:BAG52020.1};+++[F5GYR7_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000440587}; Flags: Fragment;+++[F5GZ10_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000441483}; Flags: Fragment;+++[F5GZ98_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000443855}; Flags: Fragment;+++[F5H1K9_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000439578}; Flags: Fragment;+++[F5H221_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000445604}; Flags: Fragment;+++[F5H2H9_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000446260}; Flags: Fragment;+++[F5H2W9_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000439279}; Flags: Fragment;+++[F5H3C4_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000439192}; Flags: Fragment;+++[F5H502_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000444784}; Flags: Fragment;+++[F5H592_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000444620}; Flags: Fragment;+++[F5H6X8_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000442958}; Flags: Fragment;+++[F5H8I0_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000443540}; Flags: Fragment;+++[F8WE35_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000414158}; Flags: Fragment;+++[H0YFA3_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000437711}; Flags: Fragment;"]
[55745,"'AP5M1'",494,425,389,436,{"$nulls":4},"GO:0005764///lysosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005765///lysosomal membrane+++GO:0031902///late endosome membrane+++GO:0005737///cytoplasm+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0005770///late endosome+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0015031///protein transport","adaptor related protein complex 5 subunit mu 1","[AP5M1_HUMAN|Reviewed]RecName: Full=AP-5 complex subunit mu-1; AltName: Full=Adaptor-related protein complex 5 subunit mu-1; Short=Mu5; AltName: Full=Mu-2-related death-inducing protein; Short=MuD; AltName: Full=Putative HIV-1 infection-related protein;+++[A0A024R654_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 108, isoform CRA_a {ECO:0000313|EMBL:EAW80702.1};+++[E7EQ45_HUMAN|Unreviewed]SubName: Full=AP-5 complex subunit mu-1 {ECO:0000313|Ensembl:ENSP00000390531};+++[G3V3L4_HUMAN|Unreviewed]SubName: Full=AP-5 complex subunit mu-1 {ECO:0000313|Ensembl:ENSP00000451306};+++[G3V573_HUMAN|Unreviewed]SubName: Full=AP-5 complex subunit mu-1 {ECO:0000313|Ensembl:ENSP00000452211}; Flags: Fragment;+++[H0YIY0_HUMAN|Unreviewed]SubName: Full=AP-5 complex subunit mu-1 {ECO:0000313|Ensembl:ENSP00000450422}; Flags: Fragment;+++[S4R311_HUMAN|Unreviewed]SubName: Full=AP-5 complex subunit mu-1 {ECO:0000313|Ensembl:ENSP00000473837}; Flags: Fragment;"]
[55760,"'DHX32'",602,553,517,557.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding","GO:0000398///mRNA splicing, via spliceosome","DEAH-box helicase 32 (putative)","[DHX32_HUMAN|Reviewed]RecName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32; EC=3.6.4.13; AltName: Full=DEAD/H box 32; AltName: Full=DEAD/H helicase-like protein 1; Short=DHLP1; AltName: Full=DEAH box protein 32; AltName: Full=HuDDX32;+++[X6R717_HUMAN|Unreviewed]SubName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 {ECO:0000313|Ensembl:ENSP00000357710};+++[X6RHK1_HUMAN|Unreviewed]SubName: Full=Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 {ECO:0000313|Ensembl:ENSP00000406781}; Flags: Fragment;"]
[55779,"'CFAP44'",86,121,77,94.6666666666667,{"$nulls":4},"GO:0031514///motile cilium+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0005737///cytoplasm",null,"GO:0007288///sperm axoneme assembly+++GO:0060285///cilium-dependent cell motility+++GO:0097722///sperm motility","cilia and flagella associated protein 44","[CFA44_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 44 {ECO:0000312|HGNC:HGNC:25631}; AltName: Full=WD repeat-containing protein 52 {ECO:0000312|HGNC:HGNC:25631};+++[A0A1D5RMR1_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 44 {ECO:0000313|Ensembl:ENSP00000420375}; Flags: Fragment;+++[C9K0A4_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 44 {ECO:0000313|Ensembl:ENSP00000419671}; Flags: Fragment;+++[F8WEX0_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 44 {ECO:0000313|Ensembl:ENSP00000419844};+++[H0Y883_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 44 {ECO:0000313|Ensembl:ENSP00000418257}; Flags: Fragment;+++[H0Y896_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 44 {ECO:0000313|Ensembl:ENSP00000418795}; Flags: Fragment;+++[H7C512_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 44 {ECO:0000313|Ensembl:ENSP00000418743}; Flags: Fragment;+++[H7C591_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 44 {ECO:0000313|Ensembl:ENSP00000419269}; Flags: Fragment;+++[Q9NUU0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ11142 fis, clone PLACE1006552 {ECO:0000313|EMBL:BAA92030.1};+++[Q9UF55_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434A2017 {ECO:0000313|EMBL:CAB63738.1}; Flags: Fragment;"]
[55796,"'MBNL3'",47,35,24,35.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0043484///regulation of RNA splicing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0007275///multicellular organism development+++GO:0006397///mRNA processing+++GO:0045662///negative regulation of myoblast differentiation+++GO:0008380///RNA splicing+++GO:0006357///regulation of transcription by RNA polymerase II","muscleblind like splicing regulator 3","[MBNL3_HUMAN|Reviewed]RecName: Full=Muscleblind-like protein 3; AltName: Full=Cys3His CCG1-required protein; AltName: Full=Muscleblind-like X-linked protein; AltName: Full=Protein HCHCR;+++[B1AKI2_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 3 {ECO:0000313|Ensembl:ENSP00000412065}; Flags: Fragment;+++[B1AKI4_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 3 {ECO:0000313|Ensembl:ENSP00000406014}; Flags: Fragment;+++[B1AKI5_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 3 {ECO:0000313|Ensembl:ENSP00000402128}; Flags: Fragment;+++[B1AKI6_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 3 {ECO:0000313|Ensembl:ENSP00000359894};"]
[55812,"'SPATA7'",138,128,132,132.666666666667,null,"H00837///Leber congenital amaurosis (LCR)+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0036064///ciliary basal body+++GO:0032391///photoreceptor connecting cilium+++GO:0005654///nucleoplasm+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005739///mitochondrion+++GO:0005930///axoneme","GO:0005515///protein binding","GO:0050896///response to stimulus+++GO:0045494///photoreceptor cell maintenance+++GO:1903546///protein localization to photoreceptor outer segment+++GO:0007601///visual perception+++GO:1903621///protein localization to photoreceptor connecting cilium","spermatogenesis associated 7","[SPAT7_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 7; AltName: Full=HSD-3.1; AltName: Full=Spermatogenesis-associated protein HSD3;+++[G3V287_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450515};+++[G3V2E1_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450606}; Flags: Fragment;+++[G3V2V4_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450882};+++[G3V3D2_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451181};+++[G3V491_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451663};+++[G3V4A9_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451690};+++[G3V5H6_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000452359};+++[G3V5N2_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000452435}; Flags: Fragment;+++[G3V5V8_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000452546};+++[H0YJ48_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000450809}; Flags: Fragment;+++[H0YJ93_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 7 {ECO:0000313|Ensembl:ENSP00000451019}; Flags: Fragment;+++[Q6FI63_HUMAN|Unreviewed]SubName: Full=SPATA7 protein {ECO:0000313|EMBL:CAG38594.1};+++[V9HVY9_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 296 {ECO:0000313|EMBL:ACF94506.1}; SubName: Full=Spermatogenesis associated 7, isoform CRA_f {ECO:0000313|EMBL:EAW81381.1};"]
[55837,"'EAPP'",489,491,529,503,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm",null,"GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0008284///positive regulation of cell proliferation","E2F associated phosphoprotein","[EAPP_HUMAN|Reviewed]RecName: Full=E2F-associated phosphoprotein; Short=EAPP;+++[A0A087X060_HUMAN|Unreviewed]SubName: Full=E2F-associated phosphoprotein {ECO:0000313|Ensembl:ENSP00000483122};+++[G3V2W9_HUMAN|Unreviewed]SubName: Full=E2F-associated phosphoprotein {ECO:0000313|Ensembl:ENSP00000450908}; Flags: Fragment;+++[G3V5N6_HUMAN|Unreviewed]SubName: Full=E2F-associated phosphoprotein {ECO:0000313|Ensembl:ENSP00000452439};+++[L8EAZ8_HUMAN|Unreviewed]SubName: Full=Alternative protein EAPP {ECO:0000313|EMBL:CCQ43598.1};"]
[55851,"'PSENEN'",615,666,727,669.333333333333,"05010///Alzheimer's disease+++04330///Notch signaling pathway","H00681///Acne inversa","M00682///Notch signaling",null,"GO:0005887///integral component of plasma membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0010008///endosome membrane+++GO:0032580///Golgi cisterna membrane+++GO:0070765///gamma-secretase complex+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0007220///Notch receptor processing+++GO:0035333///Notch receptor processing, ligand-dependent+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0007219///Notch signaling pathway+++GO:0034205///amyloid-beta formation+++GO:0016485///protein processing+++GO:0043085///positive regulation of catalytic activity+++GO:0042987///amyloid precursor protein catabolic process+++GO:0042982///amyloid precursor protein metabolic process","presenilin enhancer, gamma-secretase subunit","[PEN2_HUMAN|Reviewed]RecName: Full=Gamma-secretase subunit PEN-2; AltName: Full=Presenilin enhancer protein 2;+++[K7ES79_HUMAN|Unreviewed]SubName: Full=Gamma-secretase subunit PEN-2 {ECO:0000313|Ensembl:ENSP00000468593};"]
[55885,"'LMO3'",1,2,2,1.66666666666667,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:2000324///positive regulation of glucocorticoid receptor signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0070373///negative regulation of ERK1 and ERK2 cascade","LIM domain only 3","[LMO3_HUMAN|Reviewed]RecName: Full=LIM domain only protein 3; Short=LMO-3; AltName: Full=Neuronal-specific transcription factor DAT1; AltName: Full=Rhombotin-3;+++[A0A024RAT1_HUMAN|Unreviewed]SubName: Full=LIM domain only 3 (Rhombotin-like 2), isoform CRA_b {ECO:0000313|EMBL:EAW96372.1};+++[A0A024RAX3_HUMAN|Unreviewed]SubName: Full=LIM domain only 3 (Rhombotin-like 2), isoform CRA_a {ECO:0000313|EMBL:EAW96374.1};+++[A0A087WYA2_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000481643};+++[C9JE61_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000404656};+++[F5GYZ6_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000441360}; Flags: Fragment;+++[F5GZR3_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000444269}; Flags: Fragment;+++[F5H2N9_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000445504}; Flags: Fragment;+++[F5H3S4_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000445193}; Flags: Fragment;+++[F5H4K9_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000446095}; Flags: Fragment;+++[F5H4T0_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000439989}; Flags: Fragment;+++[F5H655_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000437890};+++[F6TDU8_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000439900};+++[Q05D86_HUMAN|Unreviewed]SubName: Full=LIM domain only protein 3 {ECO:0000313|Ensembl:ENSP00000404386}; SubName: Full=LMO3 protein {ECO:0000313|EMBL:AAH17777.1};+++[Q9NYC6_HUMAN|Unreviewed]SubName: Full=Neuronal specific transcription factor DAT1 {ECO:0000313|EMBL:AAF71368.1};"]
[55904,"'KMT2E'",1982.01,1879,1608,1823.00333333333,"00310///Lysine degradation",null,null,"R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005737///cytoplasm+++GO:0035327///transcriptionally active chromatin+++GO:0000785///chromatin+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005886///plasma membrane+++GO:0005694///chromosome+++GO:0005815///microtubule organizing center+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0019899///enzyme binding+++GO:0035064///methylated histone binding","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0042119///neutrophil activation+++GO:0006325///chromatin organization+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0034968///histone lysine methylation+++GO:0002446///neutrophil mediated immunity+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:0006306///DNA methylation+++GO:0030218///erythrocyte differentiation+++GO:0007049///cell cycle+++GO:1905437///positive regulation of histone H3-K4 trimethylation+++GO:0007050///cell cycle arrest","lysine methyltransferase 2E","[KMT2E_HUMAN|Reviewed]RecName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000305}; Short=Inactive lysine N-methyltransferase 2E {ECO:0000305}; AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 5;+++[A0A087WYW5_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000482147};+++[C9JNE1_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000420415}; Flags: Fragment;+++[C9JQ68_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000420206}; Flags: Fragment;+++[C9JYI9_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000419883}; Flags: Fragment;+++[F8WAU9_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000417193};+++[H7C4F3_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000417156}; Flags: Fragment;+++[H7C5C4_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000419525}; Flags: Fragment;+++[O95038_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MLL5 {ECO:0000313|EMBL:AAD04721.2}; Flags: Fragment;+++[Q86W16_HUMAN|Unreviewed]SubName: Full=MLL5 {ECO:0000313|EMBL:AAO86416.1}; Flags: Fragment;+++[S4R363_HUMAN|Unreviewed]SubName: Full=Inactive histone-lysine N-methyltransferase 2E {ECO:0000313|Ensembl:ENSP00000473963}; Flags: Fragment;"]
[5591,"'PRKDC'",3007,2704,1669,2460,"04110///Cell cycle+++03450///Non-homologous end-joining",null,"M00297///DNA-PK complex",null,"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0032993///protein-DNA complex+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070419///nonhomologous end joining complex+++GO:0005730///nucleolus+++GO:0032991///protein-containing complex+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005654///nucleoplasm+++GO:0005958///DNA-dependent protein kinase-DNA ligase 4 complex","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0003690///double-stranded DNA binding+++GO:0019904///protein domain specific binding+++GO:0004677///DNA-dependent protein kinase activity","GO:0002360///T cell lineage commitment+++GO:0006464///cellular protein modification process+++GO:0014823///response to activity+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0030098///lymphocyte differentiation+++GO:0006281///DNA repair+++GO:0010332///response to gamma radiation+++GO:0002638///negative regulation of immunoglobulin production+++GO:0001756///somitogenesis+++GO:0002218///activation of innate immune response+++GO:0033151///V(D)J recombination+++GO:0008283///cell proliferation+++GO:0048511///rhythmic process+++GO:0006302///double-strand break repair+++GO:2001229///negative regulation of response to gamma radiation+++GO:0032869///cellular response to insulin stimulus+++GO:0018105///peptidyl-serine phosphorylation+++GO:0035234///ectopic germ cell programmed cell death+++GO:0002326///B cell lineage commitment+++GO:0002328///pro-B cell differentiation+++GO:0006468///protein phosphorylation+++GO:0031648///protein destabilization+++GO:0002376///immune system process+++GO:0010212///response to ionizing radiation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0097681///double-strand break repair via alternative nonhomologous end joining+++GO:0033152///immunoglobulin V(D)J recombination+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006310///DNA recombination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045087///innate immune response+++GO:0016310///phosphorylation+++GO:2000773///negative regulation of cellular senescence+++GO:0048536///spleen development+++GO:0007507///heart development+++GO:0042752///regulation of circadian rhythm+++GO:0033153///T cell receptor V(D)J recombination+++GO:0016233///telomere capping+++GO:0033077///T cell differentiation in thymus+++GO:0007420///brain development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0002684///positive regulation of immune system process+++GO:0048538///thymus development+++GO:0043065///positive regulation of apoptotic process+++GO:0002377///immunoglobulin production+++GO:0048639///positive regulation of developmental growth+++GO:0032481///positive regulation of type I interferon production+++GO:0072431///signal transduction involved in mitotic G1 DNA damage checkpoint+++GO:0016567///protein ubiquitination+++GO:0000723///telomere maintenance","protein kinase, DNA-activated, catalytic subunit","[PRKDC_HUMAN|Reviewed]RecName: Full=DNA-dependent protein kinase catalytic subunit; Short=DNA-PK catalytic subunit; Short=DNA-PKcs; EC=2.7.11.1; AltName: Full=DNPK1; AltName: Full=p460;+++[F5GX40_HUMAN|Unreviewed]SubName: Full=DNA-dependent protein kinase catalytic subunit {ECO:0000313|Ensembl:ENSP00000441157}; Flags: Fragment;+++[H0YG84_HUMAN|Unreviewed]SubName: Full=DNA-dependent protein kinase catalytic subunit {ECO:0000313|Ensembl:ENSP00000442177}; Flags: Fragment;"]
[55970,"'GNG12'",2707,3028,2457,2730.66666666667,"04010///MAPK signaling pathway+++04727///GABAergic synapse+++04726///Serotonergic synapse+++04014///Ras signaling pathway+++04723///Retrograde endocannabinoid signaling+++04724///Glutamatergic synapse+++04810///Regulation of actin cytoskeleton+++05034///Alcoholism+++05032///Morphine addiction+++05200///Pathways in cancer+++04062///Chemokine signaling pathway+++04728///Dopaminergic synapse+++04725///Cholinergic synapse+++04151///PI3K-Akt signaling pathway+++04371///Apelin signaling pathway+++05163///Human cytomegalovirus infection+++04713///Circadian entrainment+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04926///Relaxin signaling pathway",{"$nulls":3},"GO:0005884///actin filament+++GO:0070062///extracellular exosome+++GO:0005834///heterotrimeric G-protein complex+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0042301///phosphate ion binding+++GO:0030165///PDZ domain binding+++GO:0003924///GTPase activity","GO:0021987///cerebral cortex development+++GO:0032496///response to lipopolysaccharide+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","G protein subunit gamma 12","[GBG12_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12; Flags: Precursor;"]
[5598,"'MAPK7'",864,941,963,922.666666666667,"04010///MAPK signaling pathway+++04011///MAPK signaling pathway - yeast+++04722///Neurotrophin signaling pathway+++04657///IL-17 signaling pathway+++05206///MicroRNAs in cancer+++05418///Fluid shear stress and atherosclerosis+++04139///Mitophagy - yeast+++04912///GnRH signaling pathway+++04921///Oxytocin signaling pathway+++04138///Autophagy - yeast+++04540///Gap junction",null,"M00690///MAPK (ERK5) signaling",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016605///PML body+++GO:0005654///nucleoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0051019///mitogen-activated protein kinase binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004707///MAP kinase activity+++GO:0016301///kinase activity","GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0030154///cell differentiation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0043066///negative regulation of apoptotic process+++GO:0071363///cellular response to growth factor stimulus+++GO:0010468///regulation of gene expression+++GO:0007165///signal transduction+++GO:0051247///positive regulation of protein metabolic process+++GO:0051344///negative regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0018105///peptidyl-serine phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070885///negative regulation of calcineurin-NFAT signaling cascade+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0016310///phosphorylation+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0050728///negative regulation of inflammatory response+++GO:0019933///cAMP-mediated signaling+++GO:1902176///negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway+++GO:0007049///cell cycle+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071310///cellular response to organic substance+++GO:0006468///protein phosphorylation+++GO:0007411///axon guidance+++GO:0045765///regulation of angiogenesis","mitogen-activated protein kinase 7","[MK07_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase 7; Short=MAP kinase 7; Short=MAPK 7; EC=2.7.11.24; AltName: Full=Big MAP kinase 1; Short=BMK-1; AltName: Full=Extracellular signal-regulated kinase 5; Short=ERK-5;+++[A0A024QZ20_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812};+++[C9JUK9_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812}; Flags: Fragment;+++[I3L0J8_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 7 {ECO:0000313|Ensembl:ENSP00000458146}; Flags: Fragment;+++[J3KT50_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 7 {ECO:0000313|Ensembl:ENSP00000462804};+++[J3KT61_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 7 {ECO:0000313|Ensembl:ENSP00000462819}; Flags: Fragment;+++[S4R3I1_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 7 {ECO:0000313|Ensembl:ENSP00000474397}; Flags: Fragment;"]
[56102,"'PCDHGB3'",87.83,107.69,67.69,87.7366666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","protocadherin gamma subfamily B, 3","[PCDGF_HUMAN|Reviewed]RecName: Full=Protocadherin gamma-B3; Short=PCDH-gamma-B3; Flags: Precursor;+++[L0R6M0_HUMAN|Unreviewed]SubName: Full=Alternative protein PCDHGB3 {ECO:0000313|EMBL:CCO13787.1};"]
[56109,"'PCDHGA6'",290.36,316.83,270.29,292.493333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","protocadherin gamma subfamily A, 6","[PCDG6_HUMAN|Reviewed]RecName: Full=Protocadherin gamma-A6; Short=PCDH-gamma-A6; Flags: Precursor;+++[A4IF48_HUMAN|Unreviewed]SubName: Full=PCDHGA6 protein {ECO:0000313|EMBL:AAI09241.1}; Flags: Fragment;"]
[56136,"'PCDHA13'",19.38,21.9,33.39,24.89,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","protocadherin alpha 13","[PCDAD_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-13; Short=PCDH-alpha-13; Flags: Precursor;+++[C9JA99_HUMAN|Unreviewed]SubName: Full=Protocadherin alpha-13 {ECO:0000313|Ensembl:ENSP00000386821};"]
[56145,"'PCDHA3'",19.38,19.46,18.21,19.0166666666667,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007399///nervous system development+++GO:0007155///cell adhesion","protocadherin alpha 3","[PCDA3_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-3; Short=PCDH-alpha-3; Flags: Precursor;+++[A1L2Z5_HUMAN|Unreviewed]SubName: Full=Protocadherin alpha 3 {ECO:0000313|EMBL:AAI29808.1};"]
[56243,"'KIAA1217'",4864,5110,3262,4412,{"$nulls":4},"GO:0005737///cytoplasm","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0048706///embryonic skeletal system development","KIAA1217","[SKT_HUMAN|Reviewed]RecName: Full=Sickle tail protein homolog;+++[A0A0U1RQK8_HUMAN|Unreviewed]SubName: Full=Sickle tail protein homolog {ECO:0000313|Ensembl:ENSP00000489052}; Flags: Fragment;+++[A0A0U1RRK8_HUMAN|Unreviewed]SubName: Full=Sickle tail protein homolog {ECO:0000313|Ensembl:ENSP00000489575}; Flags: Fragment;+++[A0A1B0GU17_HUMAN|Unreviewed]SubName: Full=Sickle tail protein homolog {ECO:0000313|Ensembl:ENSP00000489926}; Flags: Fragment;+++[B7ZM29_HUMAN|Unreviewed]SubName: Full=KIAA1217 protein {ECO:0000313|EMBL:AAI44228.1};+++[Q5T5P0_HUMAN|Unreviewed]SubName: Full=Sickle tail protein homolog {ECO:0000313|Ensembl:ENSP00000404798}; Flags: Fragment;+++[Q5T5P1_HUMAN|Unreviewed]SubName: Full=Sickle tail protein homolog {ECO:0000313|Ensembl:ENSP00000365639}; Flags: Fragment;"]
[56261,"'GPCPD1'",221,239,213,224.333333333333,"05231///Choline metabolism in cancer+++00564///Glycerophospholipid metabolism",null,null,"R01470///sn-Glycero-3-phosphoethanolamine glycerophosphohydrolase   sn-Glycero-3-phosphoethanolamine + H2O <=> Ethanolamine + sn-Glycerol 3-phosphate+++R01030///sn-Glycero-3-phosphocholine glycerophosphohydrolase   sn-Glycero-3-phosphocholine + H2O <=> Choline + sn-Glycerol 3-phosphate","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0030246///carbohydrate binding+++GO:0047389///glycerophosphocholine phosphodiesterase activity+++GO:2001070///starch binding+++GO:0016787///hydrolase activity+++GO:0008081///phosphoric diester hydrolase activity","GO:0007519///skeletal muscle tissue development+++GO:0006629///lipid metabolic process+++GO:0046475///glycerophospholipid catabolic process","glycerophosphocholine phosphodiesterase 1","[GPCP1_HUMAN|Reviewed]RecName: Full=Glycerophosphocholine phosphodiesterase GPCPD1; EC=3.1.4.2; AltName: Full=Glycerophosphodiester phosphodiesterase 5;+++[A0A0J9YVP8_HUMAN|Unreviewed]SubName: Full=Glycerophosphocholine phosphodiesterase GPCPD1 {ECO:0000313|Ensembl:ENSP00000487616}; Flags: Fragment;+++[A0A0J9YY12_HUMAN|Unreviewed]SubName: Full=Glycerophosphocholine phosphodiesterase GPCPD1 {ECO:0000313|Ensembl:ENSP00000488635};+++[H0Y565_HUMAN|Unreviewed]SubName: Full=Glycerophosphocholine phosphodiesterase GPCPD1 {ECO:0000313|Ensembl:ENSP00000396720}; Flags: Fragment;"]
[5639,"'PRRG2'",6,5,6,5.66666666666667,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0005515///protein binding",null,"proline rich and Gla domain 2","[TMG2_HUMAN|Reviewed]RecName: Full=Transmembrane gamma-carboxyglutamic acid protein 2; AltName: Full=Proline-rich gamma-carboxyglutamic acid protein 2; Short=Proline-rich Gla protein 2; Flags: Precursor;+++[M0QXL9_HUMAN|Unreviewed]SubName: Full=Transmembrane gamma-carboxyglutamic acid protein 2 {ECO:0000313|Ensembl:ENSP00000469258}; Flags: Fragment;+++[M0QZA1_HUMAN|Unreviewed]SubName: Full=Transmembrane gamma-carboxyglutamic acid protein 2 {ECO:0000313|Ensembl:ENSP00000470401};+++[Q8TAS3_HUMAN|Unreviewed]SubName: Full=PRRG2 protein {ECO:0000313|EMBL:AAH26032.1};"]
[5651,"'TMPRSS15'",0,0,1,0.333333333333333,null,"H00988///Enterokinase deficiency",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005903///brush border","GO:0016787///hydrolase activity+++GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0008236///serine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0004252///serine-type endopeptidase activity","GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis","transmembrane serine protease 15","[ENTK_HUMAN|Reviewed]RecName: Full=Enteropeptidase; EC=3.4.21.9; AltName: Full=Enterokinase; AltName: Full=Serine protease 7; AltName: Full=Transmembrane protease serine 15; Contains: RecName: Full=Enteropeptidase non-catalytic heavy chain; Contains: RecName: Full=Enteropeptidase catalytic light chain; Flags: Precursor;+++[E9PG70_HUMAN|Unreviewed]SubName: Full=Enteropeptidase {ECO:0000313|Ensembl:ENSP00000398253}; Flags: Fragment;+++[Q9NR95_HUMAN|Unreviewed]SubName: Full=Enteropeptidase {ECO:0000313|EMBL:AAF97778.1}; EC=3.4.21.9 {ECO:0000313|EMBL:AAF97778.1}; Flags: Fragment;"]
[5655,"'KLK10'",207,514,532,417.666666666667,{"$nulls":4},"GO:0030141///secretory granule+++GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity","GO:0006508///proteolysis+++GO:0007049///cell cycle","kallikrein related peptidase 10","[KLK10_HUMAN|Reviewed]RecName: Full=Kallikrein-10; EC=3.4.21.-; AltName: Full=Normal epithelial cell-specific 1; AltName: Full=Protease serine-like 1; Flags: Precursor;+++[A0A024R4N7_HUMAN|Unreviewed]SubName: Full=Kallikrein 10, isoform CRA_a {ECO:0000313|EMBL:EAW71969.1};+++[A0A1W5R407_HUMAN|Unreviewed]SubName: Full=Kallikrein-related peptidase 10 transcript variant 5 {ECO:0000313|EMBL:AQT40988.1};+++[M0R132_HUMAN|Unreviewed]SubName: Full=Kallikrein-10 {ECO:0000313|Ensembl:ENSP00000471610}; Flags: Fragment;+++[M0R2S4_HUMAN|Unreviewed]SubName: Full=Kallikrein-10 {ECO:0000313|Ensembl:ENSP00000472773};+++[Q6ICR6_HUMAN|Unreviewed]SubName: Full=KLK10 protein {ECO:0000313|EMBL:CAG29323.1}; SubName: Full=Kallikrein 10 splice variant 3 {ECO:0000313|EMBL:AAS66975.1}; SubName: Full=Kallikrein J {ECO:0000313|EMBL:SFW93208.1}; SubName: Full=cDNA FLJ76060, highly similar to Homo sapiens kallikrein 10 (KLK10), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF85054.1}; Flags: Fragment;+++[W8GIU9_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 1 {ECO:0000313|EMBL:AHK24361.1}; Flags: Fragment;+++[W8GIV4_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 3 {ECO:0000313|EMBL:AHK24363.1}; SubName: Full=Kallikrein 10 protein 7 {ECO:0000313|EMBL:AHK24366.1}; Flags: Fragment;+++[W8GJG4_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 13 {ECO:0000313|EMBL:AHK24360.1}; Flags: Fragment;+++[W8GJG8_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 5 {ECO:0000313|EMBL:AHK24365.1}; Flags: Fragment;+++[W8GN28_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 12 {ECO:0000313|EMBL:AHK24359.1}; Flags: Fragment;+++[W8GN33_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 4 {ECO:0000313|EMBL:AHK24364.1}; Flags: Fragment;+++[W8GRM7_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 9 {ECO:0000313|EMBL:AHK24358.1}; Flags: Fragment;+++[W8GWD1_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 8 {ECO:0000313|EMBL:AHK24357.1}; Flags: Fragment;+++[W8GWD5_HUMAN|Unreviewed]SubName: Full=Kallikrein 10 protein 2 {ECO:0000313|EMBL:AHK24362.1}; Flags: Fragment;"]
[56681,"'SAR1A'",1368,1364,1234,1322,"04141///Protein processing in endoplasmic reticulum+++05134///Legionellosis","H00927///Chylomicron retention disease (CRD)","M00404///COPII complex",null,"GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0070971///endoplasmic reticulum exit site+++GO:0005623///cell+++GO:0030127///COPII vesicle coat+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding","GO:0003400///regulation of COPII vesicle coating+++GO:0061024///membrane organization+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0016050///vesicle organization","secretion associated Ras related GTPase 1A","[SAR1A_HUMAN|Reviewed]RecName: Full=GTP-binding protein SAR1a; AltName: Full=COPII-associated small GTPase;+++[H0Y5E8_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1a {ECO:0000313|Ensembl:ENSP00000398165}; Flags: Fragment;+++[Q5SQT8_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1a {ECO:0000313|Ensembl:ENSP00000362333};+++[Q5SQT9_HUMAN|Unreviewed]SubName: Full=SAR1 gene homolog A (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW54378.1}; SubName: Full=Small GTP-binding protein {ECO:0000313|EMBL:AAL27183.1};+++[Q6FID4_HUMAN|Unreviewed]SubName: Full=SARA1 protein {ECO:0000313|EMBL:CAG38523.1};+++[X1WI22_HUMAN|Unreviewed]SubName: Full=GTP-binding protein SAR1a {ECO:0000313|Ensembl:ENSP00000362336}; Flags: Fragment;"]
[5670,"'PSG2'",4,3,6,4.33333333333333,{"$nulls":4},"GO:0005575///cellular_component+++GO:0005576///extracellular region","GO:0003674///molecular_function","GO:0007565///female pregnancy+++GO:0016477///cell migration","pregnancy specific beta-1-glycoprotein 2","[PSG2_HUMAN|Reviewed]RecName: Full=Pregnancy-specific beta-1-glycoprotein 2; Short=PS-beta-G-2; Short=PSBG-2; Short=Pregnancy-specific glycoprotein 2; AltName: Full=Pregnancy-specific beta-1 glycoprotein E; Short=PS-beta-E; Flags: Precursor;+++[A0A024R0M4_HUMAN|Unreviewed]SubName: Full=Pregnancy specific beta-1-glycoprotein 2, isoform CRA_a {ECO:0000313|EMBL:EAW57170.1};+++[A0A0A0MR77_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 2 {ECO:0000313|Ensembl:ENSP00000332984}; Flags: Fragment;+++[Q13982_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen {ECO:0000313|EMBL:AAA51965.1}; Flags: Fragment;+++[Q13984_HUMAN|Unreviewed]SubName: Full=CEA protein {ECO:0000313|EMBL:AAA51968.1}; Flags: Fragment;+++[Q13985_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen {ECO:0000313|EMBL:AAA51971.1}; Flags: Fragment;+++[Q7KZ28_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen {ECO:0000313|EMBL:AAA51964.1}; Flags: Fragment;+++[Q9UML9_HUMAN|Unreviewed]SubName: Full=CEA protein {ECO:0000313|EMBL:AAA60959.1}; Flags: Fragment;"]
[56884,"'FSTL5'",1,3,4,2.66666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0032197///transposition, RNA-mediated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination","follistatin like 5","[FSTL5_HUMAN|Reviewed]RecName: Full=Follistatin-related protein 5; AltName: Full=Follistatin-like protein 5; Flags: Precursor;"]
[56902,"'PNO1'",230.22,239.06,258.18,242.486666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding",null,"partner of NOB1 homolog","[PNO1_HUMAN|Reviewed]RecName: Full=RNA-binding protein PNO1;+++[F8WBJ6_HUMAN|Unreviewed]SubName: Full=RNA-binding protein PNO1 {ECO:0000313|Ensembl:ENSP00000405892};"]
[56905,"'C15orf39'",404,446,492,447.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04110///Cell cycle","H01772///Adrenal hypoplasia congenita+++H00713///Beckwith-Wiedemann syndrome+++H00033///Adrenal carcinoma",null,null,"GO:0005829///cytosol",null,null,"chromosome 15 open reading frame 39","[CO039_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C15orf39;+++[H3BMJ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C15orf39 {ECO:0000313|Ensembl:ENSP00000454405}; Flags: Fragment;+++[H3BN41_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C15orf39 {ECO:0000313|Ensembl:ENSP00000454677}; Flags: Fragment;+++[H3BRS2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C15orf39 {ECO:0000313|Ensembl:ENSP00000456381}; Flags: Fragment;+++[H3BT66_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C15orf39 {ECO:0000313|Ensembl:ENSP00000457045}; Flags: Fragment;+++[Q2VPA3_HUMAN|Unreviewed]SubName: Full=C15orf39 protein {ECO:0000313|EMBL:AAI09196.1}; Flags: Fragment;"]
[56920,"'SEMA3G'",6,1,2,3,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane","GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0005102///signaling receptor binding+++GO:0045499///chemorepellent activity","GO:0050919///negative chemotaxis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0030517///negative regulation of axon extension","semaphorin 3G","[SEM3G_HUMAN|Reviewed]RecName: Full=Semaphorin-3G; AltName: Full=Semaphorin sem2; Flags: Precursor;+++[C9JXB2_HUMAN|Unreviewed]SubName: Full=Semaphorin-3G {ECO:0000313|Ensembl:ENSP00000419181}; Flags: Fragment;+++[H7C5M7_HUMAN|Unreviewed]SubName: Full=Semaphorin-3G {ECO:0000313|Ensembl:ENSP00000420291}; Flags: Fragment;"]
[56942,"'CMC2'",90,104,108,100.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion",null,"GO:0007059///chromosome segregation+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0051382///kinetochore assembly","C-X9-C motif containing 2","[COXM2_HUMAN|Reviewed]RecName: Full=COX assembly mitochondrial protein 2 homolog;+++[H3BN28_HUMAN|Unreviewed]RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104};+++[H3BNN8_HUMAN|Unreviewed]RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104};+++[H3BP68_HUMAN|Unreviewed]RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104};+++[H3BPP2_HUMAN|Unreviewed]RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104};+++[H3BQQ1_HUMAN|Unreviewed]RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104}; Flags: Fragment;+++[H3BRC3_HUMAN|Unreviewed]RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104};+++[H3BTB6_HUMAN|Unreviewed]RecName: Full=COX assembly mitochondrial protein {ECO:0000256|RuleBase:RU364104};"]
[56957,"'OTUD7B'",595,528,481,534.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0003677///DNA binding+++GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0005515///protein binding+++GO:1990380///Lys48-specific deubiquitinase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity","GO:0002376///immune system process+++GO:0006508///proteolysis+++GO:0032717///negative regulation of interleukin-8 production+++GO:0071108///protein K48-linked deubiquitination+++GO:0070536///protein K63-linked deubiquitination+++GO:0002385///mucosal immune response+++GO:0002250///adaptive immune response+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0016579///protein deubiquitination+++GO:1900181///negative regulation of protein localization to nucleus+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0071947///protein deubiquitination involved in ubiquitin-dependent protein catabolic process+++GO:0035871///protein K11-linked deubiquitination","OTU deubiquitinase 7B","[OTU7B_HUMAN|Reviewed]RecName: Full=OTU domain-containing protein 7B; EC=3.4.19.12 {ECO:0000269|PubMed:12682062, ECO:0000269|PubMed:14748687, ECO:0000269|PubMed:22179831, ECO:0000269|PubMed:23827681, ECO:0000269|PubMed:26903241, ECO:0000269|PubMed:27732584}; AltName: Full=Cellular zinc finger anti-NF-kappa-B protein {ECO:0000303|PubMed:11463333}; Short=Cezanne {ECO:0000303|PubMed:11463333, ECO:0000303|PubMed:18178551, ECO:0000303|PubMed:27732584}; AltName: Full=Zinc finger A20 domain-containing protein 1; AltName: Full=Zinc finger protein Cezanne {ECO:0000305};+++[Q5SZ59_HUMAN|Unreviewed]SubName: Full=OTU domain containing 7B {ECO:0000313|EMBL:CAI12652.1}; SubName: Full=OTU domain-containing protein 7B {ECO:0000313|Ensembl:ENSP00000408231}; Flags: Fragment;"]
[56983,"'POGLUT1'",366,359,408,377.666666666667,"00514///Other types of O-glycan biosynthesis","H00593///Limb-girdle muscular dystrophy (LGMD)",null,"R09315///UDP-D-glucose + [Protein]-L-serine <=> UDP + G13051","GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0030158///protein xylosyltransferase activity+++GO:0046527///glucosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0035251///UDP-glucosyltransferase activity+++GO:0035252///UDP-xylosyltransferase activity","GO:0007369///gastrulation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0006493///protein O-linked glycosylation+++GO:0010470///regulation of gastrulation+++GO:0007275///multicellular organism development+++GO:0048318///axial mesoderm development+++GO:0006486///protein glycosylation+++GO:0008593///regulation of Notch signaling pathway+++GO:0001756///somitogenesis+++GO:0060537///muscle tissue development+++GO:0048339///paraxial mesoderm development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0072358///cardiovascular system development","protein O-glucosyltransferase 1","[PGLT1_HUMAN|Reviewed]RecName: Full=Protein O-glucosyltransferase 1 {ECO:0000305}; EC=2.4.1.- {ECO:0000269|PubMed:21490058, ECO:0000269|PubMed:21949356}; AltName: Full=CAP10-like 46 kDa protein {ECO:0000303|PubMed:16524674}; Short=hCLP46 {ECO:0000303|PubMed:16524674}; AltName: Full=KTEL motif-containing protein 1; AltName: Full=Myelodysplastic syndromes relative protein; AltName: Full=O-glucosyltransferase Rumi homolog {ECO:0000303|PubMed:21490058}; Short=hRumi {ECO:0000303|PubMed:21490058}; AltName: Full=Protein O-xylosyltransferase POGLUT1 {ECO:0000305}; EC=2.4.2.26 {ECO:0000269|PubMed:21081508, ECO:0000269|PubMed:28775322}; Flags: Precursor;+++[B4DJ97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53005, highly similar to CAP10-like 46 kDa protein {ECO:0000313|EMBL:BAG58759.1};+++[B4DVA9_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419288}; SubName: Full=cDNA FLJ53000, highly similar to CAP10-like 46 kDa protein {ECO:0000313|EMBL:BAG62621.1};+++[F8WDC4_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000420594};+++[F8WEW4_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419876};+++[H7C5H0_HUMAN|Unreviewed]SubName: Full=Protein O-glucosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000419865}; Flags: Fragment;"]
[57002,"'YAE1'",117,115,113,115,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006413///translational initiation+++GO:0106035///protein maturation by [4Fe-4S] cluster transfer+++GO:0042273///ribosomal large subunit biogenesis","YAE1, ABCE1 maturation factor","[YAE1_HUMAN|Reviewed]RecName: Full=Protein YAE1 homolog {ECO:0000305}; AltName: Full=Yae1 domain-containing protein 1;+++[C9IZ57_HUMAN|Unreviewed]SubName: Full=YAE1, ABCE1 maturation factor {ECO:0000313|Ensembl:ENSP00000400511};"]
[57038,"'RARS2'",601,572,575,582.666666666667,"00970///Aminoacyl-tRNA biosynthesis","H00679///Hypomyelinating leukodystrophy+++H00897///Pontocerebellar hypoplasia","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03646///L-Arginine:tRNA(Arg) ligase (AMP-forming)   ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)","GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004814///arginine-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000166///nucleotide binding","GO:0006420///arginyl-tRNA aminoacylation+++GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0006418///tRNA aminoacylation for protein translation","arginyl-tRNA synthetase 2, mitochondrial","[SYRM_HUMAN|Reviewed]RecName: Full=Probable arginine--tRNA ligase, mitochondrial; EC=6.1.1.19; AltName: Full=Arginyl-tRNA synthetase; Short=ArgRS; Flags: Precursor;+++[H0UI22_HUMAN|Unreviewed]SubName: Full=Arginyl-tRNA synthetase-like, isoform CRA_e {ECO:0000313|EMBL:EAW48590.1};+++[H0Y450_HUMAN|Unreviewed]SubName: Full=Probable arginine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000389656}; Flags: Fragment;"]
[5709,"'PSMD3'",2385,2698,2875,2652.66666666667,"03050///Proteasome+++05169///Epstein-Barr virus infection",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0005654///nucleoplasm+++GO:0000502///proteasome complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005838///proteasome regulatory particle+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0022624///proteasome accessory complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0034774///secretory granule lumen","GO:0030234///enzyme regulator activity+++GO:0005515///protein binding","GO:0016579///protein deubiquitination+++GO:0043687///post-translational protein modification+++GO:0042176///regulation of protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043312///neutrophil degranulation+++GO:0050790///regulation of catalytic activity","proteasome 26S subunit, non-ATPase 3","[PSMD3_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 3; AltName: Full=26S proteasome regulatory subunit RPN3; AltName: Full=26S proteasome regulatory subunit S3; AltName: Full=Proteasome subunit p58;+++[F5H8K4_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 3 {ECO:0000313|Ensembl:ENSP00000407410};+++[H0YGV8_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 3 {ECO:0000313|Ensembl:ENSP00000444980}; Flags: Fragment;+++[Q6IBN0_HUMAN|Unreviewed]SubName: Full=PSMD3 protein {ECO:0000313|EMBL:CAG33053.1};"]
[57105,"'CYSLTR2'",0,0,1,0.333333333333333,"04080///Neuroactive ligand-receptor interaction+++04020///Calcium signaling pathway",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0008528///G protein-coupled peptide receptor activity+++GO:0004974///leukotriene receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0004966///galanin receptor activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0007218///neuropeptide signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006955///immune response+++GO:0061737///leukotriene signaling pathway","cysteinyl leukotriene receptor 2","[CLTR2_HUMAN|Reviewed]RecName: Full=Cysteinyl leukotriene receptor 2; Short=CysLTR2; AltName: Full=G-protein coupled receptor GPCR21; Short=hGPCR21; AltName: Full=G-protein coupled receptor HG57; AltName: Full=HPN321;+++[A0A1B0GXM0_HUMAN|Unreviewed]SubName: Full=Cysteinyl leukotriene receptor 2 {ECO:0000313|Ensembl:ENSP00000482041}; Flags: Fragment;+++[A4ZKH2_HUMAN|Unreviewed]SubName: Full=Cysteinyl leukotriene receptor 2 splice variant I {ECO:0000313|EMBL:ABO61874.1}; Flags: Fragment;+++[Q5KU17_HUMAN|Unreviewed]SubName: Full=Cysteinyl leukotriene receptor 2 {ECO:0000313|EMBL:AAH96832.1}; SubName: Full=G-protein coupled receptor protein {ECO:0000313|EMBL:BAD83598.1}; SubName: Full=cDNA FLJ78284, highly similar to Homo sapiens cysteinyl leukotriene receptor 2 (CYSLTR2), mRNA {ECO:0000313|EMBL:BAF84428.1};"]
[57130,"'ATP13A1'",4609,5182,5337,5042.66666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane","GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0015410///manganese-transporting ATPase activity+++GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity","GO:0071421///manganese ion transmembrane transport+++GO:0006812///cation transport+++GO:0034220///ion transmembrane transport+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0008150///biological_process+++GO:0006874///cellular calcium ion homeostasis","ATPase 13A1","[AT131_HUMAN|Reviewed]RecName: Full=Manganese-transporting ATPase 13A1; EC=3.6.3.-;+++[A0A024R7N2_HUMAN|Unreviewed]RecName: Full=Cation-transporting ATPase {ECO:0000256|RuleBase:RU362082}; EC=3.6.3.- {ECO:0000256|RuleBase:RU362082};+++[A0A024R7P3_HUMAN|Unreviewed]RecName: Full=Cation-transporting ATPase {ECO:0000256|RuleBase:RU362082}; EC=3.6.3.- {ECO:0000256|RuleBase:RU362082};+++[H7C3H2_HUMAN|Unreviewed]SubName: Full=Manganese-transporting ATPase 13A1 {ECO:0000313|Ensembl:ENSP00000411891}; Flags: Fragment;"]
[57148,"'RALGAPB'",1163,1126,750,1013,{"$nulls":5},"GO:0046982///protein heterodimerization activity+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction","Ral GTPase activating protein non-catalytic beta subunit","[RLGPB_HUMAN|Reviewed]RecName: Full=Ral GTPase-activating protein subunit beta; AltName: Full=p170;+++[A0A0J9YW54_HUMAN|Unreviewed]SubName: Full=Ral GTPase-activating protein subunit beta {ECO:0000313|Ensembl:ENSP00000487816}; Flags: Fragment;+++[A2A2F0_HUMAN|Unreviewed]SubName: Full=Ral GTPase-activating protein subunit beta {ECO:0000313|Ensembl:ENSP00000416646}; Flags: Fragment;+++[G1UI28_HUMAN|Unreviewed]SubName: Full=Ral GTPase-activating protein subunit beta {ECO:0000313|EMBL:BAK64151.1}; Flags: Fragment;+++[Q6MZJ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686N19168 {ECO:0000313|EMBL:CAE46039.1};"]
[57176,"'VARS2'",268,265,294,275.666666666667,"00970///Aminoacyl-tRNA biosynthesis","H00891///Combined oxidative phosphorylation deficiency (COXPD)","M00360///Aminoacyl-tRNA biosynthesis, prokaryotes+++M00359///Aminoacyl-tRNA biosynthesis, eukaryotes","R03665///L-Valine:tRNAVal ligase (AMP-forming)   ATP + L-Valine + tRNA(Val) <=> AMP + Diphosphate + L-Valyl-tRNA(Val)","GO:0005739///mitochondrion","GO:0004832///valine-tRNA ligase activity+++GO:0002161///aminoacyl-tRNA editing activity+++GO:0005524///ATP binding","GO:0006438///valyl-tRNA aminoacylation","valyl-tRNA synthetase 2, mitochondrial","[SYVM_HUMAN|Reviewed]RecName: Full=Valine--tRNA ligase, mitochondrial; EC=6.1.1.9; AltName: Full=Valyl-tRNA synthetase; Short=ValRS; AltName: Full=Valyl-tRNA synthetase-like; Flags: Precursor;+++[A0A0A0MTG1_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000448002};+++[A0A0G2JIA5_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000396754};+++[A0A0G2JL52_HUMAN|Unreviewed]SubName: Full=VARS2 {ECO:0000313|EMBL:AQY77371.2}; SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000449382};+++[A0A140T8Y0_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000372860};+++[A0A140TA35_HUMAN|Unreviewed]SubName: Full=VARS2 {ECO:0000313|EMBL:AQY77372.2}; SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447141};+++[A0A140TA36_HUMAN|Unreviewed]SubName: Full=VARS2 {ECO:0000313|EMBL:AQY77369.2}; SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447179};+++[A0A140TA40_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000447763};+++[A0A140TA45_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000449456};+++[A0A1U9X9B3_HUMAN|Unreviewed]SubName: Full=VARS2 {ECO:0000313|EMBL:AQY77378.2};+++[A2ABL6_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000416390}; Flags: Fragment;+++[B4DG77_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53779, highly similar to Homo sapiens valyl-tRNA synthetase like (VARSL), mRNA {ECO:0000313|EMBL:BAG57688.1};+++[B4E0K6_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000373032}; SubName: Full=cDNA FLJ56191, highly similar to Homo sapiens valyl-tRNA synthetase like (VARSL), mRNA {ECO:0000313|EMBL:BAG64468.1};+++[B7ZCJ6_HUMAN|Unreviewed]SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000403749}; Flags: Fragment;+++[B7ZL25_HUMAN|Unreviewed]SubName: Full=VARS2 protein {ECO:0000313|EMBL:AAI43537.1}; SubName: Full=Valine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000446608};"]
[57188,"'ADAMTSL3'",1850,1112,969,1310.33333333333,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0008233///peptidase activity","GO:0006508///proteolysis","ADAMTS like 3","[ATL3_HUMAN|Reviewed]RecName: Full=ADAMTS-like protein 3; Short=ADAMTSL-3; AltName: Full=Punctin-2; Flags: Precursor;"]
[57223,"'PPP4R3B'",1164,973,915,1017.33333333333,"04212///Longevity regulating pathway - worm+++04922///Glucagon signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0030289///protein phosphatase 4 complex","GO:0042803///protein homodimerization activity","GO:0045722///positive regulation of gluconeogenesis+++GO:0006470///protein dephosphorylation+++GO:0019216///regulation of lipid metabolic process","protein phosphatase 4 regulatory subunit 3B","[P4R3B_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 3B; AltName: Full=SMEK homolog 2;"]
[5728,"'PTEN'",1502,1334,1150,1328.66666666667,"01521///EGFR tyrosine kinase inhibitor resistance+++05218///Melanoma+++05224///Breast cancer+++04218///Cellular senescence+++05213///Endometrial cancer+++04071///Sphingolipid signaling pathway+++05206///MicroRNAs in cancer+++05215///Prostate cancer+++04212///Longevity regulating pathway - worm+++05200///Pathways in cancer+++05214///Glioma+++05225///Hepatocellular carcinoma+++05230///Central carbon metabolism in cancer+++05165///Human papillomavirus infection+++00562///Inositol phosphate metabolism+++04151///PI3K-Akt signaling pathway+++04068///FoxO signaling pathway+++05161///Hepatitis B+++04070///Phosphatidylinositol signaling system+++04510///Focal adhesion+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++05222///Small cell lung cancer+++04115///p53 signaling pathway+++04931///Insulin resistance","H00013///Small cell lung cancer+++H01556///Meningioma+++H00539///PTEN hamartoma tumor syndrome (PHTS)+++H00042///Glioma+++H00048///Hepatocellular carcinoma+++H01195///VACTERL/VATER association+++H00031///Breast cancer+++H01463///Mycosis fungoides+++H01222///Cowden syndrome+++H00038///Melanoma+++H00024///Prostate cancer+++H00026///Endometrial cancer+++H00029///Vulvar cancer",null,"R03363///1-Phosphatidyl-1D-myo-inositol 3-phosphate 3-phosphohydrolase   1-Phosphatidyl-1D-myo-inositol 3-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate+++R04513///Phosphatidylinositol-3,4,5-trisphosphate 3-phosphohydrolase   Phosphatidylinositol-3,4,5-trisphosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + Orthophosphate","GO:0005634///nucleus+++GO:0099524///postsynaptic cytosol+++GO:0016605///PML body+++GO:0005576///extracellular region+++GO:0042995///cell projection+++GO:0035749///myelin sheath adaxonal region+++GO:1990904///ribonucleoprotein complex+++GO:0043197///dendritic spine+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005654///nucleoplasm+++GO:0016324///apical plasma membrane+++GO:0005694///chromosome+++GO:0043220///Schmidt-Lanterman incisure+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0000781///chromosome, telomeric region","GO:0042802///identical protein binding+++GO:0003723///RNA binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0016314///phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0002039///p53 binding+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0005161///platelet-derived growth factor receptor binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0070034///telomerase RNA binding+++GO:0005524///ATP binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:1990782///protein tyrosine kinase binding+++GO:0051800///phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity+++GO:0003720///telomerase activity+++GO:0010997///anaphase-promoting complex binding+++GO:0019901///protein kinase binding+++GO:0008289///lipid binding+++GO:0051717///inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0030165///PDZ domain binding+++GO:0019899///enzyme binding+++GO:0004721///phosphoprotein phosphatase activity","GO:0046621///negative regulation of organ growth+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0030534///adult behavior+++GO:0033555///multicellular organismal response to stress+++GO:0006470///protein dephosphorylation+++GO:0045666///positive regulation of neuron differentiation+++GO:0060024///rhythmic synaptic transmission+++GO:0090071///negative regulation of ribosome biogenesis+++GO:0045471///response to ethanol+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0071257///cellular response to electrical stimulus+++GO:0048681///negative regulation of axon regeneration+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:0014070///response to organic cyclic compound+++GO:0021955///central nervous system neuron axonogenesis+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0071456///cellular response to hypoxia+++GO:0032869///cellular response to insulin stimulus+++GO:0051726///regulation of cell cycle+++GO:0016579///protein deubiquitination+++GO:0016477///cell migration+++GO:0060070///canonical Wnt signaling pathway+++GO:0050765///negative regulation of phagocytosis+++GO:0043491///protein kinase B signaling+++GO:0043065///positive regulation of apoptotic process+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0007626///locomotory behavior+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0046855///inositol phosphate dephosphorylation+++GO:0007270///neuron-neuron synaptic transmission+++GO:1903984///positive regulation of TRAIL-activated apoptotic signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0046685///response to arsenic-containing substance+++GO:0042493///response to drug+++GO:0007568///aging+++GO:0048854///brain morphogenesis+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0044320///cellular response to leptin stimulus+++GO:0061002///negative regulation of dendritic spine morphogenesis+++GO:0006915///apoptotic process+++GO:2000272///negative regulation of signaling receptor activity+++GO:0014823///response to activity+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:0016311///dephosphorylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0001525///angiogenesis+++GO:0045792///negative regulation of cell size+++GO:0030336///negative regulation of cell migration+++GO:0060074///synapse maturation+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0048738///cardiac muscle tissue development+++GO:0032535///regulation of cellular component size+++GO:0035176///social behavior+++GO:0060291///long-term synaptic potentiation+++GO:0060134///prepulse inhibition+++GO:0032355///response to estradiol+++GO:0060179///male mating behavior+++GO:0010033///response to organic substance+++GO:0043542///endothelial cell migration+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0007584///response to nutrient+++GO:0050771///negative regulation of axonogenesis+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:2000808///negative regulation of synaptic vesicle clustering+++GO:0060292///long-term synaptic depression+++GO:0010975///regulation of neuron projection development+++GO:0002902///regulation of B cell apoptotic process+++GO:0097105///presynaptic membrane assembly+++GO:0021542///dentate gyrus development+++GO:0071361///cellular response to ethanol+++GO:0031175///neuron projection development+++GO:0031642///negative regulation of myelination+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0036294///cellular response to decreased oxygen levels+++GO:0031647///regulation of protein stability+++GO:0032286///central nervous system myelin maintenance+++GO:0007611///learning or memory+++GO:0060736///prostate gland growth+++GO:0007399///nervous system development+++GO:0007613///memory+++GO:0000722///telomere maintenance via recombination+++GO:0042711///maternal behavior+++GO:0006629///lipid metabolic process+++GO:0097107///postsynaptic density assembly+++GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:0050821///protein stabilization+++GO:0010628///positive regulation of gene expression+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0090344///negative regulation of cell aging+++GO:0060341///regulation of cellular localization+++GO:0008285///negative regulation of cell proliferation+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0008283///cell proliferation+++GO:0051548///negative regulation of keratinocyte migration+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0010043///response to zinc ion+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0045475///locomotor rhythm+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0007417///central nervous system development+++GO:0008284///positive regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0007507///heart development+++GO:0060997///dendritic spine morphogenesis+++GO:0048679///regulation of axon regeneration+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0007416///synapse assembly+++GO:0033032///regulation of myeloid cell apoptotic process+++GO:1903690///negative regulation of wound healing, spreading of epidermal cells+++GO:0048853///forebrain morphogenesis+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043647///inositol phosphate metabolic process+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0010035///response to inorganic substance+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0033198///response to ATP","phosphatase and tensin homolog","[PTEN_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; EC=3.1.3.16 {ECO:0000269|PubMed:9256433}; EC=3.1.3.48 {ECO:0000269|PubMed:9187108, ECO:0000269|PubMed:9256433}; EC=3.1.3.67 {ECO:0000269|PubMed:9593664, ECO:0000269|PubMed:9811831}; AltName: Full=Mutated in multiple advanced cancers 1; AltName: Full=Phosphatase and tensin homolog;+++[A0A024QYR6_HUMAN|Unreviewed]SubName: Full=Mitochondrial PTENalpha {ECO:0000313|EMBL:DAA64601.1};+++[A0A087X033_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN {ECO:0000313|Ensembl:ENSP00000483066}; Flags: Fragment;+++[A0A142FGX1_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein {ECO:0000313|EMBL:AMQ76357.1}; Flags: Fragment;+++[A0A1V0DNR7_HUMAN|Unreviewed]SubName: Full=PTENbeta {ECO:0000313|EMBL:ARB02560.1}; EC=3.1.3.67 {ECO:0000313|EMBL:ARB02560.1};+++[A0A2P0XNP6_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase {ECO:0000313|EMBL:AVE00942.1}; EC=3.1.3.67 {ECO:0000313|EMBL:AVE00942.1}; Flags: Fragment;+++[A0A2R4SE35_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase {ECO:0000313|EMBL:AVZ47052.1}; EC=3.1.3.67 {ECO:0000313|EMBL:AVZ47052.1}; Flags: Fragment;+++[F6KD01_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein {ECO:0000313|EMBL:ADM26756.1}; SubName: Full=Phosphatase and tensin-like protein isoform A {ECO:0000313|EMBL:AHW56562.1};+++[H6WA46_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein mutant variant 5 {ECO:0000313|EMBL:AEZ67438.1}; Flags: Fragment;+++[H6WA51_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein mutant variant 5 {ECO:0000313|EMBL:AEZ67433.1}; Flags: Fragment;+++[H6WA52_HUMAN|Unreviewed]SubName: Full=Phosphatase and tensin-like protein mutant variant 3 {ECO:0000313|EMBL:AEZ67431.1}; Flags: Fragment;"]
[57380,"'MRS2'",416,351,327,364.666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0015095///magnesium ion transmembrane transporter activity","GO:0015693///magnesium ion transport+++GO:0055085///transmembrane transport+++GO:0006811///ion transport+++GO:0045016///mitochondrial magnesium ion transmembrane transport","magnesium transporter MRS2","[MRS2_HUMAN|Reviewed]RecName: Full=Magnesium transporter MRS2 homolog, mitochondrial; AltName: Full=MRS2-like protein; Flags: Precursor;+++[A0A0A0MQX2_HUMAN|Unreviewed]SubName: Full=Magnesium transporter MRS2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000274747};+++[B4DSN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52740, highly similar to Magnesium transporter MRS2L, mitochondrial {ECO:0000313|EMBL:BAG61694.1};+++[H7BZ29_HUMAN|Unreviewed]SubName: Full=Magnesium transporter MRS2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000387441}; Flags: Fragment;+++[Q96KF9_HUMAN|Unreviewed]SubName: Full=Putative magnesium transporter {ECO:0000313|EMBL:AAK38616.1}; Flags: Fragment;"]
[57406,"'ABHD6'",299,300,300,299.666666666667,"04723///Retrograde endocannabinoid signaling",null,null,"R01352///2-acylglycerol acylhydrolase   2-Acylglycerol + H2O <=> Glycerol + Fatty acid","GO:0098982///GABA-ergic synapse+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0032281///AMPA glutamate receptor complex+++GO:0016021///integral component of membrane+++GO:0099055///integral component of postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion","GO:0047372///acylglycerol lipase activity+++GO:0016787///hydrolase activity+++GO:0004620///phospholipase activity+++GO:0003824///catalytic activity","GO:0046464///acylglycerol catabolic process+++GO:0009395///phospholipid catabolic process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0060292///long-term synaptic depression+++GO:0030336///negative regulation of cell migration+++GO:2000124///regulation of endocannabinoid signaling pathway+++GO:0046889///positive regulation of lipid biosynthetic process","abhydrolase domain containing 6","[ABHD6_HUMAN|Reviewed]RecName: Full=Monoacylglycerol lipase ABHD6 {ECO:0000305}; EC=3.1.1.23 {ECO:0000269|PubMed:22969151}; AltName: Full=2-arachidonoylglycerol hydrolase {ECO:0000250|UniProtKB:Q8R2Y0}; AltName: Full=Abhydrolase domain-containing protein 6 {ECO:0000312|HGNC:HGNC:21398};+++[A0A024R323_HUMAN|Unreviewed]SubName: Full=Abhydrolase domain containing 6, isoform CRA_a {ECO:0000313|EMBL:EAW65361.1};+++[C9J010_HUMAN|Unreviewed]SubName: Full=Monoacylglycerol lipase ABHD6 {ECO:0000313|Ensembl:ENSP00000418934}; Flags: Fragment;+++[C9JNE7_HUMAN|Unreviewed]SubName: Full=Monoacylglycerol lipase ABHD6 {ECO:0000313|Ensembl:ENSP00000420408}; Flags: Fragment;+++[F8WBP4_HUMAN|Unreviewed]SubName: Full=Monoacylglycerol lipase ABHD6 {ECO:0000313|Ensembl:ENSP00000418209};"]
[57415,"'C3orf14'",41,58,56,51.6666666666667,{"$nulls":7},"chromosome 3 open reading frame 14","[CC014_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C3orf14;+++[A0A024R330_HUMAN|Unreviewed]SubName: Full=Chromosome 3 open reading frame 14, isoform CRA_a {ECO:0000313|EMBL:EAW65401.1};+++[C9JY17_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C3orf14 {ECO:0000313|Ensembl:ENSP00000419937}; Flags: Fragment;"]
[57463,"'AMIGO1'",645,549,475,556.333333333333,{"$nulls":4},"GO:0032809///neuronal cell body membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0030425///dendrite+++GO:0030424///axon+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0043204///perikaryon","GO:0015459///potassium channel regulator activity","GO:0007413///axonal fasciculation+++GO:0007409///axonogenesis+++GO:0007155///cell adhesion+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007275///multicellular organism development+++GO:0042552///myelination+++GO:0050772///positive regulation of axonogenesis+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0051965///positive regulation of synapse assembly+++GO:0007399///nervous system development+++GO:0030154///cell differentiation","adhesion molecule with Ig like domain 1","[AMGO1_HUMAN|Reviewed]RecName: Full=Amphoterin-induced protein 1; AltName: Full=AMIGO-1; AltName: Full=Alivin-2; Flags: Precursor;"]
[57472,"'CNOT6'",333,331,272,312,"03018///RNA degradation",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0009897///external side of plasma membrane+++GO:0005634///nucleus+++GO:0030014///CCR4-NOT complex+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004532///exoribonuclease activity+++GO:0019956///chemokine binding+++GO:0004930///G protein-coupled receptor activity+++GO:0019957///C-C chemokine binding+++GO:0004518///nuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0046872///metal ion binding+++GO:0004527///exonuclease activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004950///chemokine receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0003723///RNA binding","GO:0070966///nuclear-transcribed mRNA catabolic process, no-go decay+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0050927///positive regulation of positive chemotaxis+++GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0006417///regulation of translation+++GO:0019722///calcium-mediated signaling+++GO:0007165///signal transduction+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0070098///chemokine-mediated signaling pathway+++GO:0046677///response to antibiotic+++GO:0002507///tolerance induction+++GO:0035195///gene silencing by miRNA+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0048872///homeostasis of number of cells+++GO:2000327///positive regulation of nuclear receptor transcription coactivator activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0060326///cell chemotaxis+++GO:0008284///positive regulation of cell proliferation+++GO:0006955///immune response+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0001764///neuron migration+++GO:0009617///response to bacterium+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009314///response to radiation+++GO:0006954///inflammatory response+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006935///chemotaxis+++GO:0031047///gene silencing by RNA","CCR4-NOT transcription complex subunit 6","[CNOT6_HUMAN|Reviewed]RecName: Full=CCR4-NOT transcription complex subunit 6; EC=3.1.13.4; AltName: Full=CCR4 carbon catabolite repression 4-like; AltName: Full=Carbon catabolite repressor protein 4 homolog; AltName: Full=Cytoplasmic deadenylase;+++[D6R9H6_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 6 {ECO:0000313|Ensembl:ENSP00000422087}; Flags: Fragment;+++[Q8TAJ0_HUMAN|Unreviewed]SubName: Full=CNOT6 protein {ECO:0000313|EMBL:AAH27476.1}; SubName: Full=cDNA, FLJ95618 {ECO:0000313|EMBL:BAG37291.1};"]
[57501,"'KIAA1257'",3,3,6,4,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00473///Mitochondrial complex I deficiency+++H00525///Disorders of mitochondrial fatty-acid oxidation+++H02085///Acyl-CoA dehydrogenase 9 deficiency",{"$nulls":5},"KIAA1257","[K1257_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA1257;+++[A0A1B0GVL5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA1257 {ECO:0000313|Ensembl:ENSP00000490565}; Flags: Fragment;+++[A0A2R8YAI9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA1257 {ECO:0000313|Ensembl:ENSP00000424951}; Flags: Fragment;+++[A0A2R8YFM9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA1257 {ECO:0000313|Ensembl:ENSP00000496592};+++[D6RH05_HUMAN|Unreviewed]SubName: Full=HCG20001, isoform CRA_b {ECO:0000313|EMBL:EAW79290.1};"]
[57513,"'CASKIN2'",969,969,917,951.666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process","CASK interacting protein 2","[CSKI2_HUMAN|Reviewed]RecName: Full=Caskin-2; AltName: Full=CASK-interacting protein 2;+++[J3QKS3_HUMAN|Unreviewed]SubName: Full=Caskin-2 {ECO:0000313|Ensembl:ENSP00000463211}; Flags: Fragment;+++[J3QRN1_HUMAN|Unreviewed]SubName: Full=Caskin-2 {ECO:0000313|Ensembl:ENSP00000464300};"]
[57534,"'MIB1'",700,605,421,575.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005813///centrosome","GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding","GO:0007219///Notch signaling pathway+++GO:0016567///protein ubiquitination+++GO:0001756///somitogenesis+++GO:0007507///heart development+++GO:0001568///blood vessel development+++GO:0001947///heart looping+++GO:0001701///in utero embryonic development+++GO:0006897///endocytosis+++GO:0045665///negative regulation of neuron differentiation+++GO:0001841///neural tube formation+++GO:0045807///positive regulation of endocytosis","mindbomb E3 ubiquitin protein ligase 1","[MIB1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MIB1; EC=2.3.2.27; AltName: Full=DAPK-interacting protein 1; Short=DIP-1; AltName: Full=Mind bomb homolog 1; AltName: Full=RING-type E3 ubiquitin transferase MIB1 {ECO:0000305}; AltName: Full=Zinc finger ZZ type with ankyrin repeat domain protein 2;+++[L8EA82_HUMAN|Unreviewed]SubName: Full=Alternative protein MIB1 {ECO:0000313|EMBL:CCQ43646.1};"]
[57556,"'SEMA6A'",83,106,92,93.6666666666667,"04360///Axon guidance",{"$nulls":3},"GO:0030424///axon+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005615///extracellular space","GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0001755///neural crest cell migration+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0016525///negative regulation of angiogenesis+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0007275///multicellular organism development+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:0007411///axon guidance+++GO:0030335///positive regulation of cell migration+++GO:0007010///cytoskeleton organization+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:2001224///positive regulation of neuron migration+++GO:0106089///negative regulation of cell adhesion involved in sprouting angiogenesis+++GO:0009887///animal organ morphogenesis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0006915///apoptotic process+++GO:0007166///cell surface receptor signaling pathway+++GO:0051642///centrosome localization+++GO:0001764///neuron migration+++GO:0030154///cell differentiation","semaphorin 6A","[SEM6A_HUMAN|Reviewed]RecName: Full=Semaphorin-6A; AltName: Full=Semaphorin VIA; Short=Sema VIA; AltName: Full=Semaphorin-6A-1; Short=SEMA6A-1; Flags: Precursor;+++[A0A0A0MQU6_HUMAN|Unreviewed]SubName: Full=Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6A, isoform CRA_d {ECO:0000313|EMBL:EAW48937.1}; SubName: Full=Semaphorin-6A {ECO:0000313|Ensembl:ENSP00000257414};+++[B3KU01_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39018 fis, clone NT2RP7002594, highly similar to Semaphorin-6A {ECO:0000313|EMBL:BAG53263.1};+++[D6RAG9_HUMAN|Unreviewed]SubName: Full=Semaphorin-6A {ECO:0000313|Ensembl:ENSP00000421935}; Flags: Fragment;+++[D6RCR0_HUMAN|Unreviewed]SubName: Full=Semaphorin-6A {ECO:0000313|Ensembl:ENSP00000425553}; Flags: Fragment;+++[E9PDV9_HUMAN|Unreviewed]SubName: Full=Semaphorin-6A {ECO:0000313|Ensembl:ENSP00000425364};+++[H0Y8V9_HUMAN|Unreviewed]SubName: Full=Semaphorin-6A {ECO:0000313|Ensembl:ENSP00000422275}; Flags: Fragment;"]
[57571,"'CARNS1'",1187,1118,1372,1225.66666666667,"00340///Histidine metabolism+++00410///beta-Alanine metabolism+++00330///Arginine and proline metabolism",null,null,"R00910///L-lysine:beta-alanine ligase (ADP-forming)   ATP + L-Lysine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-lysine+++R03286///N(pi)-methyl-L-histidine:beta-alanine ligase (ADP-forming)   ATP + N(pi)-Methyl-L-histidine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-N(pi)-methyl-L-histidine+++R01991///L-histidine:4-aminobutanoate ligase (ADP-forming)   ATP + L-Histidine + 4-Aminobutanoate <=> ADP + Orthophosphate + Homocarnosine+++R01164///L-histidine:beta-alanine ligase (ADP-forming)   ATP + L-Histidine + beta-Alanine <=> ADP + Orthophosphate + Carnosine+++R00912///L-arginine:beta-alanine ligase (ADP-forming)   ATP + L-Arginine + beta-Alanine <=> ADP + Orthophosphate + beta-Alanyl-L-arginine","GO:0005575///cellular_component+++GO:0005829///cytosol","GO:0047730///carnosine synthase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding+++GO:0010181///FMN binding+++GO:0000166///nucleotide binding+++GO:0102102///homocarnosine synthase activity+++GO:0046872///metal ion binding+++GO:0016887///ATPase activity","GO:0006548///histidine catabolic process+++GO:0035499///carnosine biosynthetic process","carnosine synthase 1","[CRNS1_HUMAN|Reviewed]RecName: Full=Carnosine synthase 1; EC=6.3.2.11; AltName: Full=ATP-grasp domain-containing protein 1;"]
[57592,"'ZNF687'",1163,1148,1123,1144.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 687","[ZN687_HUMAN|Reviewed]RecName: Full=Zinc finger protein 687;+++[A2A3Q2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 687 {ECO:0000313|Ensembl:ENSP00000395261}; Flags: Fragment;+++[A6PVV7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 687 {ECO:0000313|Ensembl:ENSP00000416942}; Flags: Fragment;+++[F8WCX2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 687 {ECO:0000313|Ensembl:ENSP00000415286};+++[H0Y5I5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 687 {ECO:0000313|Ensembl:ENSP00000398821}; Flags: Fragment;"]
[57609,"'DIP2B'",1481,1585,1039,1368.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0003824///catalytic activity+++GO:0003674///molecular_function","GO:0008150///biological_process","disco interacting protein 2 homolog B","[DIP2B_HUMAN|Reviewed]RecName: Full=Disco-interacting protein 2 homolog B; Short=DIP2 homolog B;+++[H0YIU5_HUMAN|Unreviewed]SubName: Full=Disco-interacting protein 2 homolog B {ECO:0000313|Ensembl:ENSP00000450181}; Flags: Fragment;+++[Q7Z3H2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686M1483 {ECO:0000313|EMBL:CAD97891.1}; Flags: Fragment;+++[Q96IB4_HUMAN|Unreviewed]SubName: Full=DIP2B protein {ECO:0000313|EMBL:AAH07671.2}; Flags: Fragment;"]
[57631,"'LRCH2'",179,178,161,172.666666666667,{"$nulls":4},"GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007165///signal transduction+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination","leucine rich repeats and calponin homology domain containing 2","[LRCH2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat and calponin homology domain-containing protein 2;+++[A4FVC3_HUMAN|Unreviewed]SubName: Full=LRCH2 protein {ECO:0000313|EMBL:AAI25224.1}; Flags: Fragment;"]
[57654,"'UVSSA'",184.99,145.07,105,145.02,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005694///chromosome","GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding","GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0009411///response to UV","UV stimulated scaffold protein A","[UVSSA_HUMAN|Reviewed]RecName: Full=UV-stimulated scaffold protein A;+++[H0Y924_HUMAN|Unreviewed]SubName: Full=UV-stimulated scaffold protein A {ECO:0000313|Ensembl:ENSP00000422795}; Flags: Fragment;+++[Q69YU2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434C189 {ECO:0000313|EMBL:CAH10662.1}; Flags: Fragment;"]
[5768,"'QSOX1'",10843,13608,13489,12646.6666666667,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0000139///Golgi membrane+++GO:0045171///intercellular bridge+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005623///cell+++GO:1904724///tertiary granule lumen+++GO:0031093///platelet alpha granule lumen+++GO:0035580///specific granule lumen+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane+++GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane","GO:0003756///protein disulfide isomerase activity+++GO:0016491///oxidoreductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0016972///thiol oxidase activity","GO:0016242///negative regulation of macroautophagy+++GO:0055114///oxidation-reduction process+++GO:0002576///platelet degranulation+++GO:0043312///neutrophil degranulation+++GO:0045454///cell redox homeostasis+++GO:0043687///post-translational protein modification+++GO:0044267///cellular protein metabolic process","quiescin sulfhydryl oxidase 1","[QSOX1_HUMAN|Reviewed]RecName: Full=Sulfhydryl oxidase 1; Short=hQSOX; EC=1.8.3.2; AltName: Full=Quiescin Q6; Flags: Precursor;+++[A0A140VKE5_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[A8MXT8_HUMAN|Unreviewed]SubName: Full=Sulfhydryl oxidase 1 {ECO:0000313|Ensembl:ENSP00000375883};+++[H0Y5Z8_HUMAN|Unreviewed]SubName: Full=Sulfhydryl oxidase 1 {ECO:0000313|Ensembl:ENSP00000402170}; Flags: Fragment;+++[Q13876_HUMAN|Unreviewed]SubName: Full=Bone-derived growth factor {ECO:0000313|EMBL:AAA89173.1}; Flags: Fragment;"]
[57699,"'CPNE5'",101,43,60,68,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0043025///neuronal cell body+++GO:0043204///perikaryon+++GO:0042995///cell projection+++GO:0043005///neuron projection","GO:0003674///molecular_function+++GO:0005544///calcium-dependent phospholipid binding","GO:0030154///cell differentiation+++GO:1903861///positive regulation of dendrite extension+++GO:0071277///cellular response to calcium ion","copine 5","[CPNE5_HUMAN|Reviewed]RecName: Full=Copine-5 {ECO:0000305}; AltName: Full=Copine V {ECO:0000250|UniProtKB:Q99829, ECO:0000312|HGNC:HGNC:2318};+++[A0A0J9YWA1_HUMAN|Unreviewed]SubName: Full=Copine-5 {ECO:0000313|Ensembl:ENSP00000487872}; Flags: Fragment;+++[A0A0J9YWU8_HUMAN|Unreviewed]SubName: Full=Copine-5 {ECO:0000313|Ensembl:ENSP00000488125}; Flags: Fragment;"]
[57713,"'SFMBT2'",31,28.03,20,26.3433333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016235///aggresome","GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0042393///histone binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0010629///negative regulation of gene expression+++GO:0006355///regulation of transcription, DNA-templated","Scm like with four mbt domains 2","[SMBT2_HUMAN|Reviewed]RecName: Full=Scm-like with four MBT domains protein 2; Short=Scm-like with 4 MBT domains protein 2;+++[Q5T980_HUMAN|Unreviewed]SubName: Full=Scm-like with four MBT domains protein 2 {ECO:0000313|Ensembl:ENSP00000369033};+++[Q5T981_HUMAN|Unreviewed]SubName: Full=Scm-like with four MBT domains protein 2 {ECO:0000313|Ensembl:ENSP00000369035};"]
[57716,"'PRX'",56,51,30,45.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030054///cell junction","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0008366///axon ensheathment","periaxin","[PRAX_HUMAN|Reviewed]RecName: Full=Periaxin;"]
[5781,"'PTPN11'",1965,2091,1462,1839.33333333333,"04670///Leukocyte transendothelial migration+++05211///Renal cell carcinoma+++04014///Ras signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05220///Chronic myeloid leukemia+++04931///Insulin resistance+++05205///Proteoglycans in cancer+++04625///C-type lectin receptor signaling pathway+++04013///MAPK signaling pathway - fly+++04722///Neurotrophin signaling pathway+++04630///Jak-STAT signaling pathway+++04360///Axon guidance+++04650///Natural killer cell mediated cytotoxicity+++04072///Phospholipase D signaling pathway+++05168///Herpes simplex infection+++04920///Adipocytokine signaling pathway","H01018///Metachondromatosis+++H01984///Leopard syndrome+++H01738///Noonan syndrome+++H00523///Noonan syndrome and related disorders",null,null,"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0019904///protein domain specific binding+++GO:0031748///D1 dopamine receptor binding+++GO:0051428///peptide hormone receptor binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:1990782///protein tyrosine kinase binding+++GO:0001784///phosphotyrosine residue binding+++GO:0005158///insulin receptor binding+++GO:0004726///non-membrane spanning protein tyrosine phosphatase activity+++GO:0019901///protein kinase binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0043560///insulin receptor substrate binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0043274///phospholipase binding+++GO:0016787///hydrolase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0016791///phosphatase activity","GO:0048839///inner ear development+++GO:0033629///negative regulation of cell adhesion mediated by integrin+++GO:0021697///cerebellar cortex formation+++GO:0032728///positive regulation of interferon-beta production+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0033628///regulation of cell adhesion mediated by integrin+++GO:0046825///regulation of protein export from nucleus+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0000077///DNA damage checkpoint+++GO:0007420///brain development+++GO:0032528///microvillus organization+++GO:0030220///platelet formation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0030168///platelet activation+++GO:0050900///leukocyte migration+++GO:0060338///regulation of type I interferon-mediated signaling pathway+++GO:0036302///atrioventricular canal development+++GO:0035265///organ growth+++GO:0042445///hormone metabolic process+++GO:0006470///protein dephosphorylation+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0006641///triglyceride metabolic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0007409///axonogenesis+++GO:0006629///lipid metabolic process+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0046887///positive regulation of hormone secretion+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0060325///face morphogenesis+++GO:0035855///megakaryocyte development+++GO:0038127///ERBB signaling pathway+++GO:0048609///multicellular organismal reproductive process+++GO:0061582///intestinal epithelial cell migration+++GO:0016311///dephosphorylation+++GO:0040014///regulation of multicellular organism growth+++GO:0009755///hormone-mediated signaling pathway+++GO:0071345///cellular response to cytokine stimulus+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0051463///negative regulation of cortisol secretion+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0009967///positive regulation of signal transduction+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0048806///genitalia development+++GO:0035264///multicellular organism growth+++GO:0046676///negative regulation of insulin secretion+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0046326///positive regulation of glucose import+++GO:0033277///abortive mitotic cell cycle+++GO:0043254///regulation of protein complex assembly+++GO:0042593///glucose homeostasis+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0060125///negative regulation of growth hormone secretion+++GO:0048013///ephrin receptor signaling pathway+++GO:0000187///activation of MAPK activity+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007229///integrin-mediated signaling pathway+++GO:0060020///Bergmann glial cell differentiation+++GO:0007411///axon guidance+++GO:0071260///cellular response to mechanical stimulus+++GO:0031295///T cell costimulation+++GO:0046888///negative regulation of hormone secretion+++GO:0007507///heart development+++GO:0071364///cellular response to epidermal growth factor stimulus","protein tyrosine phosphatase, non-receptor type 11","[PTN11_HUMAN|Reviewed]RecName: Full=Tyrosine-protein phosphatase non-receptor type 11; EC=3.1.3.48 {ECO:0000269|PubMed:26742426, ECO:0000269|PubMed:28074573}; AltName: Full=Protein-tyrosine phosphatase 1D; Short=PTP-1D; AltName: Full=Protein-tyrosine phosphatase 2C; Short=PTP-2C; AltName: Full=SH-PTP2; Short=SHP-2; Short=Shp2; AltName: Full=SH-PTP3;+++[A0A0U1RRI0_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 11 {ECO:0000313|Ensembl:ENSP00000489541}; Flags: Fragment;+++[A0A1W2PPU4_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 11 {ECO:0000313|Ensembl:ENSP00000491593};+++[B3GUD3_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase-2 {ECO:0000313|EMBL:ACE60554.1}; Flags: Fragment;+++[B3GUD4_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase-2 {ECO:0000313|EMBL:ACE60555.1}; Flags: Fragment;+++[B3GUD5_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase-2 {ECO:0000313|EMBL:ACE60556.1};+++[H0YF12_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein phosphatase non-receptor type 11 {ECO:0000313|Ensembl:ENSP00000437013}; Flags: Fragment;+++[Q96I26_HUMAN|Unreviewed]SubName: Full=PTPN11 protein {ECO:0000313|EMBL:AAH25181.1}; SubName: Full=cDNA, FLJ92431 {ECO:0000313|EMBL:BAG35082.1};"]
[57820,"'CCNB1IP1'",192,192,208,197.333333333333,"03410///Base excision repair+++04212///Longevity regulating pathway - worm+++04217///Necroptosis+++04210///Apoptosis+++04214///Apoptosis - fly",null,"M00296///BER complex",null,"GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity","GO:0016567///protein ubiquitination+++GO:0007131///reciprocal meiotic recombination+++GO:0051026///chiasma assembly+++GO:0001825///blastocyst formation+++GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle","cyclin B1 interacting protein 1","[CIP1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase CCNB1IP1; EC=2.3.2.27 {ECO:0000269|PubMed:12612082}; AltName: Full=Cyclin-B1-interacting protein 1; AltName: Full=Human enhancer of invasion 10; AltName: Full=RING-type E3 ubiquitin transferase CCNB1IP1 {ECO:0000305};+++[G3V5E6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000452312}; Flags: Fragment;+++[G3V5Q4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000452463};+++[G3V5S3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000452486}; Flags: Fragment;+++[H0YJ70_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000450914}; Flags: Fragment;+++[H0YJB2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000451122}; Flags: Fragment;"]
[57864,"'SLC46A2'",3,0,0,1,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface","GO:0015293///symporter activity+++GO:0005215///transporter activity","GO:0048538///thymus development+++GO:0045580///regulation of T cell differentiation+++GO:0055085///transmembrane transport+++GO:0070233///negative regulation of T cell apoptotic process+++GO:0043029///T cell homeostasis","solute carrier family 46 member 2","[TSCOT_HUMAN|Reviewed]RecName: Full=Thymic stromal cotransporter homolog; AltName: Full=Solute carrier family 46 member 2;+++[A0A024QYV1_HUMAN|Unreviewed]SubName: Full=Thymic stromal co-transporter, isoform CRA_a {ECO:0000313|EMBL:EAW50552.1};+++[S4R3Y2_HUMAN|Unreviewed]SubName: Full=Thymic stromal cotransporter homolog {ECO:0000313|Ensembl:ENSP00000474847};"]
[5802,"'PTPRS'",4214,4052,3079,3781.66666666667,{"$nulls":4},"GO:0030054///cell junction+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0045202///synapse+++GO:0031410///cytoplasmic vesicle+++GO:0099061///integral component of postsynaptic density membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0043005///neuron projection+++GO:0014069///postsynaptic density+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0030424///axon+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0043204///perikaryon+++GO:0030672///synaptic vesicle membrane","GO:0016787///hydrolase activity+++GO:0008201///heparin binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0035374///chondroitin sulfate binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding","GO:0032687///negative regulation of interferon-alpha production+++GO:0022038///corpus callosum development+++GO:0007155///cell adhesion+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0006470///protein dephosphorylation+++GO:0048671///negative regulation of collateral sprouting+++GO:0021766///hippocampus development+++GO:0099151///regulation of postsynaptic density assembly+++GO:0034164///negative regulation of toll-like receptor 9 signaling pathway+++GO:0032688///negative regulation of interferon-beta production+++GO:0030517///negative regulation of axon extension+++GO:0016311///dephosphorylation+++GO:0021549///cerebellum development+++GO:0050808///synapse organization+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0061000///negative regulation of dendritic spine development+++GO:0048681///negative regulation of axon regeneration+++GO:0010977///negative regulation of neuron projection development+++GO:0021987///cerebral cortex development+++GO:0099560///synaptic membrane adhesion+++GO:0021510///spinal cord development","protein tyrosine phosphatase, receptor type S","[PTPRS_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase S; Short=R-PTP-S; EC=3.1.3.48 {ECO:0000269|PubMed:8524829, ECO:0000305|PubMed:8992885}; AltName: Full=Receptor-type tyrosine-protein phosphatase sigma; Short=R-PTP-sigma; Flags: Precursor;+++[A0A0A0MR60_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase S {ECO:0000313|Ensembl:ENSP00000327313};+++[A8E4L7_HUMAN|Unreviewed]SubName: Full=PTPRS protein {ECO:0000313|EMBL:AAI48298.1}; Flags: Fragment;+++[D6W632_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase, receptor type, S, isoform CRA_b {ECO:0000313|EMBL:EAW69177.1};+++[D6W633_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase, receptor type, S, isoform CRA_a {ECO:0000313|EMBL:EAW69179.1};+++[G8JL96_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase S {ECO:0000313|Ensembl:ENSP00000262963};+++[K7ERX4_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase S {ECO:0000313|Ensembl:ENSP00000468455}; Flags: Fragment;+++[K7ESP0_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase S {ECO:0000313|Ensembl:ENSP00000468803}; Flags: Fragment;+++[L8E8Y3_HUMAN|Unreviewed]SubName: Full=Alternative protein PTPRS {ECO:0000313|EMBL:CCQ43191.1};+++[L8EAN4_HUMAN|Unreviewed]SubName: Full=Alternative protein PTPRS {ECO:0000313|EMBL:CCQ43821.1};+++[Q59FX6_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase, receptor type, sigma isoform 3 variant {ECO:0000313|EMBL:BAD92570.1}; Flags: Fragment;+++[Q8NHS7_HUMAN|Unreviewed]SubName: Full=PTPRS protein {ECO:0000313|EMBL:AAH29496.1}; SubName: Full=Receptor-type tyrosine-protein phosphatase S {ECO:0000313|Ensembl:ENSP00000465185};"]
[58189,"'WFDC1'",8387,5982,8190,7519.66666666667,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0003674///molecular_function+++GO:0030414///peptidase inhibitor activity","GO:0032355///response to estradiol+++GO:0061045///negative regulation of wound healing+++GO:0010951///negative regulation of endopeptidase activity+++GO:0042493///response to drug+++GO:0030308///negative regulation of cell growth+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0010466///negative regulation of peptidase activity+++GO:0001558///regulation of cell growth","WAP four-disulfide core domain 1","[WFDC1_HUMAN|Reviewed]RecName: Full=WAP four-disulfide core domain protein 1; AltName: Full=Prostate stromal protein ps20; AltName: Full=ps20 growth inhibitor; Flags: Precursor;+++[A0A087WY77_HUMAN|Unreviewed]SubName: Full=WAP four-disulfide core domain protein 1 {ECO:0000313|Ensembl:ENSP00000481580};"]
[58472,"'SQOR'",178,194,243,205,"00920///Sulfur metabolism+++01120///Microbial metabolism in diverse environments","H00166///Hermansky-Pudlak syndrome (HPS)",null,"R11929///sulfide:glutathione,quinone oxidoreductase   Hydrogen sulfide + Glutathione + Quinone <=> S-Sulfanylglutathione + Hydroquinone","GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0071949///FAD binding+++GO:0016491///oxidoreductase activity+++GO:0048038///quinone binding+++GO:0070224///sulfide:quinone oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0070221///sulfide oxidation, using sulfide:quinone oxidoreductase+++GO:0070813///hydrogen sulfide metabolic process","sulfide quinone oxidoreductase","[SQOR_HUMAN|Reviewed]RecName: Full=Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000305}; Short=SQOR {ECO:0000312|HGNC:HGNC:20390}; EC=1.8.5.- {ECO:0000269|PubMed:22852582}; AltName: Full=Sulfide dehydrogenase-like; AltName: Full=Sulfide quinone oxidoreductase {ECO:0000312|HGNC:HGNC:20390}; Flags: Precursor;+++[A0A024R5X2_HUMAN|Unreviewed]SubName: Full=HCG2001986, isoform CRA_a {ECO:0000313|EMBL:EAW77324.1};+++[A0A1B0GXB4_HUMAN|Unreviewed]SubName: Full=Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456075}; Flags: Fragment;+++[H3BMS6_HUMAN|Unreviewed]SubName: Full=Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000313|Ensembl:ENSP00000454520}; Flags: Fragment;+++[H3BNP9_HUMAN|Unreviewed]SubName: Full=Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000313|Ensembl:ENSP00000454953}; Flags: Fragment;+++[H3BT21_HUMAN|Unreviewed]SubName: Full=Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456979}; Flags: Fragment;+++[H3BUD7_HUMAN|Unreviewed]SubName: Full=Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457592}; Flags: Fragment;+++[H3BV36_HUMAN|Unreviewed]SubName: Full=Sulfide:quinone oxidoreductase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457937}; Flags: Fragment;"]
[58490,"'RPRD1B'",419,452,354,408.333333333333,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding+++GO:0042802///identical protein binding","GO:0010564///regulation of cell cycle process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain+++GO:0008284///positive regulation of cell proliferation","regulation of nuclear pre-mRNA domain containing 1B","[RPR1B_HUMAN|Reviewed]RecName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B; AltName: Full=Cell cycle-related and expression-elevated protein in tumor;+++[A0A087WUK3_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000478724}; Flags: Fragment;+++[A0A087X2D2_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000484897}; Flags: Fragment;+++[A2A2M0_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000416420}; Flags: Fragment;+++[E9PIQ9_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000433947};+++[E9PQF3_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000436816};"]
[58517,"'RBM25'",1714,1727,1594,1678.33333333333,"03040///Spliceosome",{"$nulls":3},"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003676///nucleic acid binding","GO:0042981///regulation of apoptotic process+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 25","[RBM25_HUMAN|Reviewed]RecName: Full=RNA-binding protein 25; AltName: Full=Arg/Glu/Asp-rich protein of 120 kDa; Short=RED120; AltName: Full=Protein S164; AltName: Full=RNA-binding motif protein 25; AltName: Full=RNA-binding region-containing protein 7;+++[E9PQU5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 25 {ECO:0000313|Ensembl:ENSP00000434333}; Flags: Fragment;+++[E9PSE8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 25 {ECO:0000313|Ensembl:ENSP00000434004}; Flags: Fragment;+++[H0YE46_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 25 {ECO:0000313|Ensembl:ENSP00000434950}; Flags: Fragment;+++[L8EB35_HUMAN|Unreviewed]SubName: Full=Alternative protein RBM25 {ECO:0000313|EMBL:CCQ43668.1};"]
[5860,"'QDPR'",421,398,424,414.333333333333,"00790///Folate biosynthesis+++01100///Metabolic pathways","H00167///Phenylketonuria (PKU)",null,"R01793///5,6,7,8-tetrahydrobiopterin:NAD+ oxidoreductase   Dihydrobiopterin + NADH + H+ <=> Tetrahydrobiopterin + NAD++++R01794///5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase   Dihydrobiopterin + NADPH + H+ <=> Tetrahydrobiopterin + NADP+","GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection+++GO:0005737///cytoplasm","GO:0070402///NADPH binding+++GO:0009055///electron transfer activity+++GO:0004155///6,7-dihydropteridine reductase activity+++GO:0070404///NADH binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity","GO:0010044///response to aluminum ion+++GO:0001889///liver development+++GO:0010288///response to lead ion+++GO:0055114///oxidation-reduction process+++GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0006559///L-phenylalanine catabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0022900///electron transport chain+++GO:0051066///dihydrobiopterin metabolic process+++GO:0035690///cellular response to drug+++GO:0033762///response to glucagon","quinoid dihydropteridine reductase","[DHPR_HUMAN|Reviewed]RecName: Full=Dihydropteridine reductase; EC=1.5.1.34; AltName: Full=HDHPR; AltName: Full=Quinoid dihydropteridine reductase; AltName: Full=Short chain dehydrogenase/reductase family 33C member 1;+++[A0A140VKA9_HUMAN|Unreviewed]SubName: Full=Testis secretory sperm-binding protein Li 236P {ECO:0000313|EMBL:AEE61246.1};+++[B7Z415_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000422759}; SubName: Full=Quinoid dihydropteridine reductase, isoform CRA_c {ECO:0000313|EMBL:EAW92776.1}; SubName: Full=cDNA FLJ55000, highly similar to Dihydropteridine reductase {ECO:0000313|EMBL:BAH12401.1};+++[D6RGG7_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000426377};+++[D6RHJ7_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000426039};+++[H0Y8F7_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000420873}; Flags: Fragment;"]
[5883,"'RAD9A'",119,142,187,149.333333333333,"04218///Cellular senescence",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0030896///checkpoint clamp complex","GO:0042826///histone deacetylase binding+++GO:0017124///SH3 domain binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0019901///protein kinase binding+++GO:0019899///enzyme binding+++GO:0008853///exodeoxyribonuclease III activity+++GO:0004527///exonuclease activity+++GO:0008408///3'-5' exonuclease activity+++GO:0004518///nuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0071479///cellular response to ionizing radiation+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000077///DNA damage checkpoint+++GO:0000076///DNA replication checkpoint+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0031573///intra-S DNA damage checkpoint","RAD9 checkpoint clamp component A","[RAD9A_HUMAN|Reviewed]RecName: Full=Cell cycle checkpoint control protein RAD9A; Short=hRAD9; EC=3.1.11.2; AltName: Full=DNA repair exonuclease rad9 homolog A;+++[A0A0G2JMD0_HUMAN|Unreviewed]SubName: Full=Cell cycle checkpoint control protein RAD9A {ECO:0000313|Ensembl:ENSP00000478994}; Flags: Fragment;+++[C4TNW7_HUMAN|Unreviewed]SubName: Full=RAD9 homolog A (S. pombe) {ECO:0000313|EMBL:BAH69085.1}; Flags: Fragment;+++[C4TNW8_HUMAN|Unreviewed]SubName: Full=RAD9 homolog A (S. pombe) {ECO:0000313|EMBL:BAH69086.1}; Flags: Fragment;+++[F5H492_HUMAN|Unreviewed]SubName: Full=Cell cycle checkpoint control protein RAD9A {ECO:0000313|Ensembl:ENSP00000445137};+++[F5H4F1_HUMAN|Unreviewed]SubName: Full=Cell cycle checkpoint control protein RAD9A {ECO:0000313|Ensembl:ENSP00000444979}; Flags: Fragment;+++[F5H8A2_HUMAN|Unreviewed]SubName: Full=Cell cycle checkpoint control protein RAD9A {ECO:0000313|Ensembl:ENSP00000442064};"]
[5899,"'RALB'",396,387,375,386,"04015///Rap1 signaling pathway+++05210///Colorectal cancer+++05212///Pancreatic cancer+++04014///Ras signaling pathway+++05200///Pathways in cancer+++04072///Phospholipase D signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0030496///midbody","GO:0000166///nucleotide binding+++GO:0051117///ATPase binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0019003///GDP binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding","GO:0051301///cell division+++GO:0060178///regulation of exocyst localization+++GO:0032091///negative regulation of protein binding+++GO:2000786///positive regulation of autophagosome assembly+++GO:0071360///cellular response to exogenous dsRNA+++GO:0009267///cellular response to starvation+++GO:0006915///apoptotic process+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001928///regulation of exocyst assembly+++GO:0032092///positive regulation of protein binding+++GO:0007049///cell cycle+++GO:0007265///Ras protein signal transduction+++GO:0007165///signal transduction","RAS like proto-oncogene B","[RALB_HUMAN|Reviewed]RecName: Full=Ras-related protein Ral-B; Flags: Precursor;+++[A0A024RAG3_HUMAN|Unreviewed]SubName: Full=V-ral simian leukemia viral oncogene homolog B (Ras related GTP binding protein), isoform CRA_a {ECO:0000313|EMBL:EAW95241.1};+++[C9J6B1_HUMAN|Unreviewed]SubName: Full=Ras-related protein Ral-B {ECO:0000313|Ensembl:ENSP00000398162}; Flags: Fragment;+++[C9JQB3_HUMAN|Unreviewed]SubName: Full=Ras-related protein Ral-B {ECO:0000313|Ensembl:ENSP00000402866}; Flags: Fragment;+++[C9JYR1_HUMAN|Unreviewed]SubName: Full=Ras-related protein Ral-B {ECO:0000313|Ensembl:ENSP00000407062}; Flags: Fragment;+++[F8WEQ6_HUMAN|Unreviewed]SubName: Full=Ras-related protein Ral-B {ECO:0000313|Ensembl:ENSP00000393782};+++[L8E7S5_HUMAN|Unreviewed]SubName: Full=Alternative protein RALB {ECO:0000313|EMBL:CCQ43194.1};"]
[5906,"'RAP1A'",317,296,328,313.666666666667,"05211///Renal cell carcinoma+++04722///Neurotrophin signaling pathway+++04530///Tight junction+++04934///Cushing's syndrome+++04670///Leukocyte transendothelial migration+++04024///cAMP signaling pathway+++04014///Ras signaling pathway+++04510///Focal adhesion+++04062///Chemokine signaling pathway+++04010///MAPK signaling pathway+++04611///Platelet activation+++04015///Rap1 signaling pathway+++04720///Long-term potentiation+++04972///Pancreatic secretion",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0005768///endosome+++GO:0005770///late endosome+++GO:0005769///early endosome+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0045335///phagocytic vesicle+++GO:0043209///myelin sheath+++GO:0098978///glutamatergic synapse+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0017034///Rap guanyl-nucleotide exchange factor activity+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0008565///protein transporter activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0017016///Ras GTPase binding+++GO:0005525///GTP binding","GO:0030033///microvillus assembly+++GO:0043312///neutrophil degranulation+++GO:0071320///cellular response to cAMP+++GO:0007165///signal transduction+++GO:0071407///cellular response to organic cyclic compound+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:0050796///regulation of insulin secretion+++GO:0097421///liver regeneration+++GO:0007264///small GTPase mediated signal transduction+++GO:0097327///response to antineoplastic agent+++GO:0032486///Rap protein signal transduction+++GO:0038180///nerve growth factor signaling pathway+++GO:0035690///cellular response to drug+++GO:0061028///establishment of endothelial barrier+++GO:2000301///negative regulation of synaptic vesicle exocytosis+++GO:0045860///positive regulation of protein kinase activity+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0010976///positive regulation of neuron projection development+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901888///regulation of cell junction assembly+++GO:2001214///positive regulation of vasculogenesis+++GO:0007399///nervous system development+++GO:0071333///cellular response to glucose stimulus+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:1905451///positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0043547///positive regulation of GTPase activity+++GO:0046326///positive regulation of glucose import+++GO:0015031///protein transport+++GO:0009743///response to carbohydrate","RAP1A, member of RAS oncogene family","[RAP1A_HUMAN|Reviewed]RecName: Full=Ras-related protein Rap-1A; AltName: Full=C21KG; AltName: Full=G-22K; AltName: Full=GTP-binding protein smg p21A; AltName: Full=Ras-related protein Krev-1; Flags: Precursor;+++[A0A075B6Q0_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rap-1A {ECO:0000313|Ensembl:ENSP00000396741}; Flags: Fragment;+++[A8KAH9_HUMAN|Unreviewed]SubName: Full=RAP1A, member of RAS oncogene family {ECO:0000313|EMBL:EAW56503.1}; SubName: Full=Ras-related protein Rap-1A {ECO:0000313|EMBL:BAG70049.1}; SubName: Full=cDNA FLJ75985, highly similar to Homo sapiens RAP1A, member of RAS oncogene family (RAP1A), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF85733.1};"]
[59274,"'TLNRD1'",956,683,936,858.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001725///stress fiber","GO:0003779///actin binding",null,"talin rod domain containing 1","[TLRN1_HUMAN|Reviewed]RecName: Full=Talin rod domain-containing protein 1 {ECO:0000305}; AltName: Full=Mesoderm development candidate 1 {ECO:0000312|HGNC:HGNC:13519};"]
[5929,"'RBBP5'",244.03,274,205.06,241.03,"04934///Cushing's syndrome",{"$nulls":3},"GO:0048188///Set1C/COMPASS complex+++GO:0005654///nucleoplasm+++GO:0035097///histone methyltransferase complex+++GO:0044666///MLL3/4 complex+++GO:0005730///nucleolus+++GO:0071339///MLL1 complex+++GO:0005634///nucleus","GO:0018024///histone-lysine N-methyltransferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0044212///transcription regulatory region DNA binding+++GO:0035064///methylated histone binding+++GO:0005515///protein binding","GO:0043627///response to estrogen+++GO:0006325///chromatin organization+++GO:0045652///regulation of megakaryocyte differentiation+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051568///histone H3-K4 methylation+++GO:0043687///post-translational protein modification","RB binding protein 5, histone lysine methyltransferase complex subunit","[RBBP5_HUMAN|Reviewed]RecName: Full=Retinoblastoma-binding protein 5; Short=RBBP-5; AltName: Full=Retinoblastoma-binding protein RBQ-3;+++[A0A024R9B5_HUMAN|Unreviewed]SubName: Full=Retinoblastoma binding protein 5, isoform CRA_b {ECO:0000313|EMBL:EAW91539.1};+++[B4DLF8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60295, highly similar to Retinoblastoma-binding protein 5 {ECO:0000313|EMBL:BAG59520.1};"]
[5940,"'RBMY1A1'",0,0,2,0.666666666666667,{"$nulls":4},"GO:1990904///ribonucleoprotein complex+++GO:0005686///U2 snRNP+++GO:0005634///nucleus","GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding","GO:0008380///RNA splicing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0051259///protein complex oligomerization+++GO:0000398///mRNA splicing, via spliceosome+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0045292///mRNA cis splicing, via spliceosome","RNA binding motif protein, Y-linked, family 1, member A1","[RBY1A_HUMAN|Reviewed]RecName: Full=RNA-binding motif protein, Y chromosome, family 1 member A1; AltName: Full=RNA-binding motif protein 1; AltName: Full=RNA-binding motif protein 2; AltName: Full=Y chromosome RNA recognition motif 1; Short=hRBMY;+++[B2RUT9_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein, Y-linked, family 1, member A1 {ECO:0000313|EMBL:AAI46854.1}; SubName: Full=RNA binding motif protein, Y-linked, family 1, member B {ECO:0000313|EMBL:AAI44578.1};"]
[5954,"'RCN1'",5403,6907,5871,6060.33333333333,{"$nulls":4},"GO:0005783///endoplasmic reticulum","GO:0005509///calcium ion binding","GO:0001701///in utero embryonic development+++GO:0043010///camera-type eye development","reticulocalbin 1","[RCN1_HUMAN|Reviewed]RecName: Full=Reticulocalbin-1; Flags: Precursor;+++[E9PLM2_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-1 {ECO:0000313|Ensembl:ENSP00000433249}; Flags: Fragment;+++[H0YDA4_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-1 {ECO:0000313|Ensembl:ENSP00000433237}; Flags: Fragment;+++[H0YER5_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-1 {ECO:0000313|Ensembl:ENSP00000436427}; Flags: Fragment;+++[V9HW95_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 84 {ECO:0000313|EMBL:ACI46038.1};"]
[5973,"'RENBP'",370,396,398,388,"00520///Amino sugar and nucleotide sugar metabolism",null,null,"R01207///N-acetyl-D-glucosamine 2-epimerase   N-Acetyl-D-glucosamine <=> N-Acetyl-D-mannosamine","GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0030414///peptidase inhibitor activity+++GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0016853///isomerase activity+++GO:0004866///endopeptidase inhibitor activity+++GO:0050121///N-acylglucosamine 2-epimerase activity+++GO:0003824///catalytic activity+++GO:0004857///enzyme inhibitor activity+++GO:0017076///purine nucleotide binding","GO:0006044///N-acetylglucosamine metabolic process+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0006051///N-acetylmannosamine metabolic process+++GO:0010951///negative regulation of endopeptidase activity+++GO:0008217///regulation of blood pressure+++GO:0043086///negative regulation of catalytic activity+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process","renin binding protein","[RENBP_HUMAN|Reviewed]RecName: Full=N-acylglucosamine 2-epimerase; Short=AGE; EC=5.1.3.8; AltName: Full=GlcNAc 2-epimerase; AltName: Full=N-acetyl-D-glucosamine 2-epimerase; AltName: Full=Renin-binding protein; Short=RnBP;+++[A6NKZ2_HUMAN|Unreviewed]SubName: Full=N-acylglucosamine 2-epimerase {ECO:0000313|Ensembl:ENSP00000359014};+++[F8WE83_HUMAN|Unreviewed]SubName: Full=N-acylglucosamine 2-epimerase {ECO:0000313|Ensembl:ENSP00000394220};+++[H7C1A7_HUMAN|Unreviewed]SubName: Full=N-acylglucosamine 2-epimerase {ECO:0000313|Ensembl:ENSP00000399278}; Flags: Fragment;+++[H7C2G7_HUMAN|Unreviewed]SubName: Full=N-acylglucosamine 2-epimerase {ECO:0000313|Ensembl:ENSP00000405759}; Flags: Fragment;+++[H7C317_HUMAN|Unreviewed]SubName: Full=N-acylglucosamine 2-epimerase {ECO:0000313|Ensembl:ENSP00000409034}; Flags: Fragment;"]
[5997,"'RGS2'",5,20,23,16,"04921///Oxytocin signaling pathway+++04740///Olfactory transduction+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005096///GTPase activator activity+++GO:0048487///beta-tubulin binding+++GO:0005516///calmodulin binding+++GO:0001965///G-protein alpha-subunit binding","GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0060452///positive regulation of cardiac muscle contraction+++GO:0140194///negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process+++GO:0061052///negative regulation of cell growth involved in cardiac muscle cell development+++GO:0045471///response to ethanol+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0007283///spermatogenesis+++GO:0055119///relaxation of cardiac muscle+++GO:0001975///response to amphetamine+++GO:0007049///cell cycle+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0017148///negative regulation of translation+++GO:0010976///positive regulation of neuron projection development+++GO:0050873///brown fat cell differentiation+++GO:0007420///brain development+++GO:1900924///negative regulation of glycine import across plasma membrane+++GO:0043407///negative regulation of MAP kinase activity+++GO:0060087///relaxation of vascular smooth muscle+++GO:0010519///negative regulation of phospholipase activity+++GO:0030728///ovulation+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0060135///maternal process involved in female pregnancy","regulator of G protein signaling 2","[RGS2_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 2; Short=RGS2; AltName: Full=Cell growth-inhibiting gene 31 protein; AltName: Full=G0/G1 switch regulatory protein 8;+++[A0A024R939_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein signalling 2, 24kDa, isoform CRA_a {ECO:0000313|EMBL:EAW91232.1};"]
[6011,"'GRK1'",1,1,1,1,"04062///Chemokine signaling pathway+++04744///Phototransduction+++04144///Endocytosis","H00787///Congenital stationary night blindness (CSNB)",null,null,"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0097381///photoreceptor disc membrane","GO:0004703///G protein-coupled receptor kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0008020///G protein-coupled photoreceptor activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0050254///rhodopsin kinase activity","GO:0050896///response to stimulus+++GO:0007601///visual perception+++GO:0046777///protein autophosphorylation+++GO:0007165///signal transduction+++GO:0016310///phosphorylation+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0006468///protein phosphorylation+++GO:0016057///regulation of membrane potential in photoreceptor cell+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0016058///maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling+++GO:0022400///regulation of rhodopsin mediated signaling pathway","G protein-coupled receptor kinase 1","[RK_HUMAN|Reviewed]RecName: Full=Rhodopsin kinase; Short=RK; EC=2.7.11.14 {ECO:0000269|PubMed:15946941}; AltName: Full=G protein-coupled receptor kinase 1 {ECO:0000312|HGNC:HGNC:10013}; Flags: Precursor;+++[A0A0J9YXB6_HUMAN|Unreviewed]RecName: Full=G protein-coupled receptor kinase {ECO:0000256|RuleBase:RU000308}; EC=2.7.11.- {ECO:0000256|RuleBase:RU000308}; Flags: Fragment;+++[B9EIS4_HUMAN|Unreviewed]RecName: Full=G protein-coupled receptor kinase {ECO:0000256|RuleBase:RU000308}; EC=2.7.11.- {ECO:0000256|RuleBase:RU000308};+++[O95098_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase 1b {ECO:0000313|EMBL:AAC97160.1}; Flags: Fragment;+++[Q71VB6_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase 1 {ECO:0000313|EMBL:AAC97161.1}; Flags: Fragment;"]
[60412,"'EXOC4'",1444,1497,1309,1416.66666666667,{"$nulls":4},"GO:0032584///growth cone membrane+++GO:0016020///membrane+++GO:0035748///myelin sheath abaxonal region+++GO:0000145///exocyst+++GO:0005737///cytoplasm+++GO:0090543///Flemming body+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0005902///microvillus+++GO:0042995///cell projection+++GO:0005886///plasma membrane","GO:0030165///PDZ domain binding+++GO:0017160///Ral GTPase binding+++GO:0047485///protein N-terminus binding+++GO:0005515///protein binding","GO:0006893///Golgi to plasma membrane transport+++GO:0015031///protein transport+++GO:0090522///vesicle tethering involved in exocytosis+++GO:0006887///exocytosis+++GO:0006904///vesicle docking involved in exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0006612///protein targeting to membrane+++GO:0048341///paraxial mesoderm formation+++GO:0016241///regulation of macroautophagy","exocyst complex component 4","[EXOC4_HUMAN|Reviewed]RecName: Full=Exocyst complex component 4; AltName: Full=Exocyst complex component Sec8;+++[Q6NX51_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 4 {ECO:0000313|EMBL:AAH67263.1};+++[Q6PJ82_HUMAN|Unreviewed]SubName: Full=EXOC4 protein {ECO:0000313|EMBL:AAH20607.1}; Flags: Fragment;+++[Q8TAR2_HUMAN|Unreviewed]SubName: Full=EXOC4 protein {ECO:0000313|EMBL:AAH26174.1};"]
[6049,"'RNF6'",644,690,505,613,{"$nulls":4},"GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031965///nuclear membrane+++GO:0030424///axon+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0050681///androgen receptor binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030517///negative regulation of axon extension+++GO:0006355///regulation of transcription, DNA-templated+++GO:0044314///protein K27-linked ubiquitination+++GO:0085020///protein K6-linked ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0060765///regulation of androgen receptor signaling pathway+++GO:0016567///protein ubiquitination","ring finger protein 6","[RNF6_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF6; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase RNF6 {ECO:0000305};+++[A0A024RDP2_HUMAN|Unreviewed]SubName: Full=Ring finger protein (C3H2C3 type) 6, isoform CRA_a {ECO:0000313|EMBL:EAX08383.1}; SubName: Full=Ring finger protein 6 isoform 1 {ECO:0000313|EMBL:ALQ33767.1};+++[A0A0S2Z4G9_HUMAN|Unreviewed]SubName: Full=Ring finger protein 6 isoform 2 {ECO:0000313|EMBL:ALQ33768.1};"]
[60561,"'RINT1'",234,214,173,207,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070939///Dsl1/NZR complex+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization+++GO:0015031///protein transport+++GO:1902504///regulation of signal transduction involved in mitotic G2 DNA damage checkpoint+++GO:0016192///vesicle-mediated transport+++GO:0048193///Golgi vesicle transport+++GO:0007049///cell cycle","RAD50 interactor 1","[RINT1_HUMAN|Reviewed]RecName: Full=RAD50-interacting protein 1; AltName: Full=RAD50 interactor 1; Short=HsRINT-1; Short=RINT-1;+++[C9J5S3_HUMAN|Unreviewed]SubName: Full=RAD50-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000417954}; Flags: Fragment;+++[F8WAZ2_HUMAN|Unreviewed]SubName: Full=RAD50-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000417107};+++[F8WC46_HUMAN|Unreviewed]SubName: Full=RAD50-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000418805};+++[F8WDC5_HUMAN|Unreviewed]SubName: Full=RAD50-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000420582};"]
[60681,"'FKBP10'",8252,9982,9342,9192,null,"H00506///Osteogenesis imperfecta+++H00514///Bruck syndrome",null,null,"GO:0005788///endoplasmic reticulum lumen+++GO:0005783///endoplasmic reticulum","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0016853///isomerase activity+++GO:0005528///FK506 binding","GO:0018208///peptidyl-proline modification+++GO:0000413///protein peptidyl-prolyl isomerization","FK506 binding protein 10","[FKB10_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP10; Short=PPIase FKBP10; EC=5.2.1.8; AltName: Full=65 kDa FK506-binding protein; Short=65 kDa FKBP; Short=FKBP-65; AltName: Full=FK506-binding protein 10; Short=FKBP-10; AltName: Full=Immunophilin FKBP65; AltName: Full=Rotamase; Flags: Precursor;+++[A0A024R1W3_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};+++[C9JPC3_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277}; Flags: Fragment;+++[H0Y827_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277}; Flags: Fragment;+++[K7ELI6_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277}; Flags: Fragment;+++[K7EM43_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};+++[K7ESG6_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277}; Flags: Fragment;+++[Q658U4_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};+++[Q8NAG5_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};"]
[6102,"'RP2'",107,113.16,74,98.0533333333333,null,"H00527///Retinitis pigmentosa (RP)",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0005929///cilium+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0036064///ciliary basal body+++GO:1990075///periciliary membrane compartment+++GO:0005814///centriole+++GO:0016604///nuclear body+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0005525///GTP binding+++GO:0051082///unfolded protein binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0007601///visual perception+++GO:0006457///protein folding+++GO:0000902///cell morphogenesis","RP2, ARL3 GTPase activating protein","[XRP2_HUMAN|Reviewed]RecName: Full=Protein XRP2;+++[A0A1B2JLU2_HUMAN|Unreviewed]RecName: Full=Protein XRP2 {ECO:0000256|PIRNR:PIRNR037947};"]
[613037,"'NPIPB13'",419.56,337.26,290.2,349.006666666667,"04137///Mitophagy - animal+++03015///mRNA surveillance pathway+++01100///Metabolic pathways+++00650///Butanoate metabolism+++04140///Autophagy - animal",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0042162///telomeric DNA binding+++GO:0003723///RNA binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0046872///metal ion binding","GO:0018105///peptidyl-serine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0006406///mRNA export from nucleus+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0032204///regulation of telomere maintenance+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","nuclear pore complex interacting protein family, member B13","[NPB13_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000312|HGNC:HGNC:41989};+++[A0A1P7U241_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000455364}; Flags: Fragment;+++[F5GW90_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000444728};+++[H3BQU5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000455945}; Flags: Fragment;"]
[6152,"'RPL24'",4469.95,4729.23,5481.79,4893.65666666667,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0042788///polysomal ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse",null,"GO:0007093///mitotic cell cycle checkpoint+++GO:0021554///optic nerve development+++GO:0002181///cytoplasmic translation+++GO:0010458///exit from mitosis+++GO:0000027///ribosomal large subunit assembly+++GO:0031290///retinal ganglion cell axon guidance+++GO:0060041///retina development in camera-type eye","ribosomal protein L24","[RL24_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L24; AltName: Full=60S ribosomal protein L30; AltName: Full=Large ribosomal subunit protein eL24 {ECO:0000303|PubMed:24524803};+++[V9HW01_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 310 {ECO:0000313|EMBL:ACF94494.1};"]
[6171,"'RPL41'",14571.51,14857.42,17566.46,15665.13,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0005829///cytosol+++GO:0042788///polysomal ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005840///ribosome","GO:0048027///mRNA 5'-UTR binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0006413///translational initiation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0002181///cytoplasmic translation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006412///translation","ribosomal protein L41","[RL41_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L41; AltName: Full=HG12; AltName: Full=Large ribosomal subunit protein eL41 {ECO:0000303|PubMed:24524803};+++[A0A024RB15_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L41 {ECO:0000313|Ensembl:ENSP00000484734}; SubName: Full=Ribosomal protein L41, isoform CRA_a {ECO:0000313|EMBL:EAW96887.1};"]
[6192,"'RPS4Y1'",1861,1825,1915,1867,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0016020///membrane+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding","GO:0006412///translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0007275///multicellular organism development+++GO:0006413///translational initiation","ribosomal protein S4 Y-linked 1","[RS4Y1_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S4, Y isoform 1; AltName: Full=Small ribosomal subunit protein eS4 {ECO:0000303|PubMed:24524803};+++[A4FU11_HUMAN|Unreviewed]SubName: Full=RPS4Y1 protein {ECO:0000313|EMBL:AAI00907.1}; Flags: Fragment;+++[C9JEH7_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S4, Y isoform 1 {ECO:0000313|Ensembl:ENSP00000415317}; Flags: Fragment;+++[Q496E4_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein S4 {ECO:0000256|PIRNR:PIRNR002116};"]
[6209,"'RPS15'",5303,5712,6390,5801.66666666667,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005840///ribosome+++GO:0045202///synapse+++GO:0015935///small ribosomal subunit+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0006413///translational initiation+++GO:0097421///liver regeneration+++GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0042274///ribosomal small subunit biogenesis+++GO:0006364///rRNA processing+++GO:0001649///osteoblast differentiation+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","ribosomal protein S15","[RS15_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S15; AltName: Full=RIG protein; AltName: Full=Small ribosomal subunit protein uS19 {ECO:0000303|PubMed:24524803};+++[A0A0B4J2B4_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000473953}; SubName: Full=Ribosomal protein S15, isoform CRA_a {ECO:0000313|EMBL:EAW69499.1};+++[A0A1Y8EIB3_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000483399}; Flags: Fragment;+++[K7EJ78_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000465055};+++[K7ELC2_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000466010};+++[K7EM56_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000466366};+++[K7EQJ5_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000467855};+++[S4R417_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000474970};+++[S4R456_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S15 {ECO:0000313|Ensembl:ENSP00000475096}; Flags: Fragment;"]
[6231,"'RPS26'",12761.87,13825.78,17926.37,14838.0066666667,"03010///Ribosome","H00237///Diamond-Blackfan anemia (DBA)","M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0022627///cytosolic small ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane","GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome","GO:0002181///cytoplasmic translation","ribosomal protein S26","[RS26_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S26; AltName: Full=Small ribosomal subunit protein eS26 {ECO:0000303|PubMed:24524803};+++[A0A024RB14_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein S26 {ECO:0000256|RuleBase:RU363128};"]
[6258,"'RXRG'",10,8,15,11,"05216///Thyroid cancer+++05222///Small cell lung cancer+++05202///Transcriptional misregulation in cancer+++04919///Thyroid hormone signaling pathway+++04659///Th17 cell differentiation+++05223///Non-small cell lung cancer+++03320///PPAR signaling pathway+++04920///Adipocytokine signaling pathway+++05200///Pathways in cancer+++05226///Gastric cancer+++04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003707///steroid hormone receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0004886///9-cis retinoic acid receptor activity+++GO:0046872///metal ion binding","GO:0043401///steroid hormone mediated signaling pathway+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter","retinoid X receptor gamma","[RXRG_HUMAN|Reviewed]RecName: Full=Retinoic acid receptor RXR-gamma; AltName: Full=Nuclear receptor subfamily 2 group B member 3; AltName: Full=Retinoid X receptor gamma;+++[A0A087WZ88_HUMAN|Unreviewed]SubName: Full=Retinoic acid receptor RXR-gamma {ECO:0000313|Ensembl:ENSP00000482458};+++[B6ZGT6_HUMAN|Unreviewed]SubName: Full=Retinoid X receptor-gamma {ECO:0000313|EMBL:BAH02297.1};+++[F1D8Q7_HUMAN|Unreviewed]SubName: Full=Retinoic acid receptor RXR-gamma {ECO:0000313|EMBL:BAJ83970.1}; SubName: Full=Retinoid X nuclear receptor gamma variant 1 {ECO:0000313|EMBL:ADZ17356.1};+++[F1T097_HUMAN|Unreviewed]SubName: Full=Retinoic acid receptor RXR-gamma {ECO:0000313|EMBL:BAJ83971.1};"]
[6259,"'RYK'",716,719,599,678,"04360///Axon guidance",{"$nulls":3},"GO:0005634///nucleus+++GO:0043235///receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0005109///frizzled binding+++GO:0000166///nucleotide binding+++GO:1904929///coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway+++GO:0042813///Wnt-activated receptor activity+++GO:0016740///transferase activity+++GO:0017147///Wnt-protein binding+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0004888///transmembrane signaling receptor activity","GO:0033278///cell proliferation in midbrain+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:1904938///planar cell polarity pathway involved in axon guidance+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0007416///synapse assembly+++GO:0030154///cell differentiation+++GO:0048705///skeletal system morphogenesis+++GO:0007411///axon guidance+++GO:0043410///positive regulation of MAPK cascade+++GO:0031175///neuron projection development+++GO:0016310///phosphorylation+++GO:0036518///chemorepulsion of dopaminergic neuron axon+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007165///signal transduction+++GO:1904948///midbrain dopaminergic neuron differentiation+++GO:0060070///canonical Wnt signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0050919///negative chemotaxis+++GO:0007409///axonogenesis+++GO:0006468///protein phosphorylation+++GO:0030182///neuron differentiation+++GO:0071679///commissural neuron axon guidance+++GO:1904953///Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation+++GO:0016055///Wnt signaling pathway+++GO:0022008///neurogenesis+++GO:0022038///corpus callosum development+++GO:0009968///negative regulation of signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation","receptor-like tyrosine kinase","[RYK_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase RYK {ECO:0000305}; EC=2.7.10.1 {ECO:0000255|PROSITE-ProRule:PRU00159}; Flags: Precursor;+++[A0A0D9SFZ4_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase RYK {ECO:0000313|Ensembl:ENSP00000487023}; Flags: Fragment;+++[H0Y8A4_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase RYK {ECO:0000313|Ensembl:ENSP00000419122}; Flags: Fragment;+++[H7C4P6_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase RYK {ECO:0000313|Ensembl:ENSP00000417836}; Flags: Fragment;+++[Q59FQ5_HUMAN|Unreviewed]SubName: Full=RYK receptor-like tyrosine kinase isoform 1 variant {ECO:0000313|EMBL:BAD92642.1}; Flags: Fragment;+++[Q8WTZ8_HUMAN|Unreviewed]SubName: Full=RYK protein {ECO:0000313|EMBL:AAH21700.2}; Flags: Fragment;"]
[63027,"'SLC22A23'",809,650,635,698,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity+++GO:0005215///transporter activity","GO:0006811///ion transport+++GO:0055085///transmembrane transport","solute carrier family 22 member 23","[S22AN_HUMAN|Reviewed]RecName: Full=Solute carrier family 22 member 23;+++[C9IZW5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000418985}; Flags: Fragment;+++[C9J4Z0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000410245};+++[F8WBC7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000417737};+++[H7C4T9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 22 member 23 {ECO:0000313|Ensembl:ENSP00000418134}; Flags: Fragment;+++[Q7L9D0_HUMAN|Unreviewed]SubName: Full=SLC22A23 protein {ECO:0000313|EMBL:AAH22217.1}; SubName: Full=cDNA: FLJ21380 fis, clone COL03329 {ECO:0000313|EMBL:BAB15054.1}; SubName: Full=cDNA: FLJ22174 fis, clone HRC00767 {ECO:0000313|EMBL:BAB15250.1};+++[Q9UFY2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434F011 {ECO:0000313|EMBL:CAB53695.1}; Flags: Fragment;"]
[6309,"'SC5D'",1523,2210,1494,1742.33333333333,"01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++00100///Steroid biosynthesis","H01281///Lathosterolosis","M00101///Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol+++M00102///Ergocalciferol biosynthesis","R07491///episterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating   Episterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5-Dehydroepisterol + 2 Ferricytochrome b5 + 2 H2O+++R07215///lathosterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating   Lathosterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 7-Dehydrocholesterol + 2 Ferricytochrome b5 + 2 H2O+++R07505///episterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating   Episterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5,7,24(28)-Ergostatrienol + 2 Ferricytochrome b5 + 2 H2O+++R07486///delta7-avenasterol,ferrocytochrome b5:oxygen oxidoreductase 5,6-dehydrogenating   Delta7-Avenasterol + 2 Ferrocytochrome b5 + Oxygen + 2 H+ <=> 5-Dehydroavenasterol + 2 Ferricytochrome b5 + 2 H2O","GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0016491///oxidoreductase activity+++GO:0005506///iron ion binding+++GO:0000248///C-5 sterol desaturase activity","GO:0055114///oxidation-reduction process+++GO:0033490///cholesterol biosynthetic process via lathosterol+++GO:0016126///sterol biosynthetic process+++GO:0008202///steroid metabolic process+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0033489///cholesterol biosynthetic process via desmosterol+++GO:0008610///lipid biosynthetic process+++GO:0006694///steroid biosynthetic process","sterol-C5-desaturase","[SC5D_HUMAN|Reviewed]RecName: Full=Lathosterol oxidase; EC=1.14.19.20; AltName: Full=C-5 sterol desaturase; AltName: Full=Delta(7)-sterol 5-desaturase; AltName: Full=Delta(7)-sterol C5(6)-desaturase; AltName: Full=Lathosterol 5-desaturase; AltName: Full=Sterol-C5-desaturase;+++[A0A024R3G4_HUMAN|Unreviewed]SubName: Full=Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like, isoform CRA_b {ECO:0000313|EMBL:EAW67522.1};+++[E9PPW5_HUMAN|Unreviewed]SubName: Full=Lathosterol oxidase {ECO:0000313|Ensembl:ENSP00000436290}; Flags: Fragment;+++[E9PQ91_HUMAN|Unreviewed]SubName: Full=Lathosterol oxidase {ECO:0000313|Ensembl:ENSP00000432550};"]
[6343,"'SCT'",46,57,63,55.3333333333333,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005179///hormone activity+++GO:0047485///protein N-terminus binding+++GO:0001664///G protein-coupled receptor binding","GO:0090274///positive regulation of somatostatin secretion+++GO:0048566///embryonic digestive tract development+++GO:1903640///negative regulation of gastrin-induced gastric acid secretion+++GO:0007420///brain development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030157///pancreatic juice secretion+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0090187///positive regulation of pancreatic juice secretion","secretin","[SECR_HUMAN|Reviewed]RecName: Full=Secretin; Flags: Precursor;"]
[6364,"'CCL20'",0,0,1,0.333333333333333,"04062///Chemokine signaling pathway+++05323///Rheumatoid arthritis+++04657///IL-17 signaling pathway+++04668///TNF signaling pathway+++04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0048020///CCR chemokine receptor binding+++GO:0008009///chemokine activity+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0031731///CCR6 chemokine receptor binding","GO:0042742///defense response to bacterium+++GO:0070098///chemokine-mediated signaling pathway+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0006954///inflammatory response+++GO:0006935///chemotaxis+++GO:2000406///positive regulation of T cell migration+++GO:0072678///T cell migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0071346///cellular response to interferon-gamma+++GO:0002548///monocyte chemotaxis+++GO:0071347///cellular response to interleukin-1+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0072679///thymocyte migration+++GO:0007165///signal transduction+++GO:0060326///cell chemotaxis+++GO:0071356///cellular response to tumor necrosis factor+++GO:0006955///immune response+++GO:0007267///cell-cell signaling+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0048247///lymphocyte chemotaxis+++GO:0010469///regulation of signaling receptor activity+++GO:0043547///positive regulation of GTPase activity+++GO:0030593///neutrophil chemotaxis+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide","C-C motif chemokine ligand 20","[CCL20_HUMAN|Reviewed]RecName: Full=C-C motif chemokine 20; AltName: Full=Beta-chemokine exodus-1; AltName: Full=CC chemokine LARC; AltName: Full=Liver and activation-regulated chemokine; AltName: Full=Macrophage inflammatory protein 3 alpha; Short=MIP-3-alpha; AltName: Full=Small-inducible cytokine A20; Contains: RecName: Full=CCL20(1-67); Contains: RecName: Full=CCL20(1-64); Contains: RecName: Full=CCL20(2-70); Flags: Precursor;+++[A0A2R8Y806_HUMAN|Unreviewed]SubName: Full=C-C motif chemokine 20 {ECO:0000313|Ensembl:ENSP00000496658}; Flags: Fragment;"]
[63892,"'THADA'",311,316,312,313,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00511///Short rib-polydactyly syndrome+++H02157///Short-rib thoracic dysplasia",null,null,"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0098554///cytoplasmic side of endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0055088///lipid homeostasis+++GO:1990845///adaptive thermogenesis+++GO:1901895///negative regulation of calcium-transporting ATPase activity+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0030488///tRNA methylation","THADA, armadillo repeat containing","[THADA_HUMAN|Reviewed]RecName: Full=Thyroid adenoma-associated protein; AltName: Full=Gene inducing thyroid adenomas protein;+++[B5MC89_HUMAN|Unreviewed]SubName: Full=Thyroid adenoma-associated protein {ECO:0000313|Ensembl:ENSP00000385469};+++[B6ZDE5_HUMAN|Unreviewed]SubName: Full=Thyroid adenoma-associated protein {ECO:0000313|Ensembl:ENSP00000384172};+++[F5H3M9_HUMAN|Unreviewed]SubName: Full=Thyroid adenoma-associated protein {ECO:0000313|Ensembl:ENSP00000445294};+++[H0Y3V5_HUMAN|Unreviewed]SubName: Full=Thyroid adenoma-associated protein {ECO:0000313|Ensembl:ENSP00000386112}; Flags: Fragment;+++[H7BYZ4_HUMAN|Unreviewed]SubName: Full=Thyroid adenoma-associated protein {ECO:0000313|Ensembl:ENSP00000385003}; Flags: Fragment;"]
[6390,"'SDHB'",734,652,711,699,"00020///Citrate cycle (TCA cycle)+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00190///Oxidative phosphorylation+++01120///Microbial metabolism in diverse environments+++05010///Alzheimer's disease+++04714///Thermogenesis+++01100///Metabolic pathways+++01200///Carbon metabolism+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05016///Huntington's disease+++05012///Parkinson's disease","H01510///Malignant paraganglioma+++H01222///Cowden syndrome","M00148///Succinate dehydrogenase (ubiquinone)+++M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00011///Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate","R02164///succinate:quinone oxidoreductase   Quinone + Succinate <=> Hydroquinone + Fumarate","GO:0016020///membrane+++GO:0045273///respiratory chain complex II+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0005749///mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)","GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0008177///succinate dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0048039///ubiquinone binding+++GO:0005515///protein binding+++GO:0051536///iron-sulfur cluster binding+++GO:0046872///metal ion binding+++GO:0009055///electron transfer activity+++GO:0051538///3 iron, 4 sulfur cluster binding","GO:0006105///succinate metabolic process+++GO:0022900///electron transport chain+++GO:0022904///respiratory electron transport chain+++GO:0009060///aerobic respiration+++GO:0006099///tricarboxylic acid cycle+++GO:0055114///oxidation-reduction process","succinate dehydrogenase complex iron sulfur subunit B","[SDHB_HUMAN|Reviewed]RecName: Full=Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; EC=1.3.5.1; AltName: Full=Iron-sulfur subunit of complex II; Short=Ip; Flags: Precursor;+++[A0A087WWT1_HUMAN|Unreviewed]RecName: Full=Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial {ECO:0000256|RuleBase:RU361237}; EC=1.3.5.1 {ECO:0000256|RuleBase:RU361237}; Flags: Fragment;+++[A0A087WXX8_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000481376}; Flags: Fragment;+++[Q70SX8_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) {ECO:0000313|EMBL:CAE47739.1}; EC=1.3.5.1 {ECO:0000313|EMBL:CAE47739.1}; Flags: Fragment;"]
[63939,"'FAM217B'",206.43,154.35,107.2,155.993333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04910///Insulin signaling pathway+++04931///Insulin resistance",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0004722///protein serine/threonine phosphatase activity+++GO:0019899///enzyme binding","GO:0005977///glycogen metabolic process+++GO:0005979///regulation of glycogen biosynthetic process+++GO:0005981///regulation of glycogen catabolic process","family with sequence similarity 217 member B","[F217B_HUMAN|Reviewed]RecName: Full=Protein FAM217B;+++[A2A2M7_HUMAN|Unreviewed]SubName: Full=Protein FAM217B {ECO:0000313|Ensembl:ENSP00000414543}; Flags: Fragment;+++[B4E2D0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57295 {ECO:0000313|EMBL:BAG65092.1};+++[Q05CU2_HUMAN|Unreviewed]SubName: Full=C20orf177 protein {ECO:0000313|EMBL:AAH20771.1}; Flags: Fragment;"]
[63967,"'CLSPN'",3.8,6.16,7.95,5.97,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0010997///anaphase-promoting complex binding+++GO:0003677///DNA binding","GO:0018105///peptidyl-serine phosphorylation+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0006260///DNA replication+++GO:0032147///activation of protein kinase activity+++GO:0000077///DNA damage checkpoint+++GO:0016579///protein deubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0033314///mitotic DNA replication checkpoint","claspin","[CLSPN_HUMAN|Reviewed]RecName: Full=Claspin; Short=hClaspin;+++[E7ESG2_HUMAN|Unreviewed]SubName: Full=Claspin {ECO:0000313|Ensembl:ENSP00000428848};+++[Q05D30_HUMAN|Unreviewed]SubName: Full=CLSPN protein {ECO:0000313|EMBL:AAH18670.1}; Flags: Fragment;+++[Q1RMC5_HUMAN|Unreviewed]SubName: Full=Claspin homolog (Xenopus laevis) {ECO:0000313|EMBL:AAI15027.1};"]
[64073,"'C19orf33'",298,409,442,383,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0003690///double-stranded DNA binding+++GO:0003697///single-stranded DNA binding","GO:0008150///biological_process","chromosome 19 open reading frame 33","[IMUP_HUMAN|Reviewed]RecName: Full=Immortalization up-regulated protein; AltName: Full=Hepatocyte growth factor activator inhibitor type 2-related small protein; Short=H2RSP; Short=HAI-2-related small protein;"]
[64093,"'SMOC1'",18,40,39,32.3333333333333,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0005576///extracellular region+++GO:0005604///basement membrane","GO:0050840///extracellular matrix binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0060173///limb development+++GO:0007275///multicellular organism development+++GO:0001654///eye development+++GO:0030154///cell differentiation+++GO:0045667///regulation of osteoblast differentiation","SPARC related modular calcium binding 1","[SMOC1_HUMAN|Reviewed]RecName: Full=SPARC-related modular calcium-binding protein 1; AltName: Full=Secreted modular calcium-binding protein 1; Short=SMOC-1; Flags: Precursor;+++[A0A024R6E0_HUMAN|Unreviewed]SubName: Full=SPARC related modular calcium binding 1, isoform CRA_b {ECO:0000313|EMBL:EAW81015.1};"]
[64105,"'CENPK'",8,5,7,6.66666666666667,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0000775///chromosome, centromeric region+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0000777///condensed chromosome kinetochore","GO:0005515///protein binding","GO:0051382///kinetochore assembly+++GO:0034080///CENP-A containing nucleosome assembly","centromere protein K","[CENPK_HUMAN|Reviewed]RecName: Full=Centromere protein K; Short=CENP-K; AltName: Full=Interphase centromere complex protein 37; AltName: Full=Protein AF-5alpha; AltName: Full=p33;+++[D6R984_HUMAN|Unreviewed]SubName: Full=Centromere protein K {ECO:0000313|Ensembl:ENSP00000423308};+++[D6RAX0_HUMAN|Unreviewed]SubName: Full=Centromere protein K {ECO:0000313|Ensembl:ENSP00000424686}; Flags: Fragment;+++[D6RBN6_HUMAN|Unreviewed]SubName: Full=Centromere protein K {ECO:0000313|Ensembl:ENSP00000424039};+++[D6RC76_HUMAN|Unreviewed]SubName: Full=Centromere protein K {ECO:0000313|Ensembl:ENSP00000422365}; Flags: Fragment;+++[D6RHD3_HUMAN|Unreviewed]SubName: Full=Centromere protein K {ECO:0000313|Ensembl:ENSP00000421034};+++[D6RJF0_HUMAN|Unreviewed]SubName: Full=Centromere protein K {ECO:0000313|Ensembl:ENSP00000425686};+++[H0Y9K8_HUMAN|Unreviewed]SubName: Full=Centromere protein K {ECO:0000313|Ensembl:ENSP00000424450}; Flags: Fragment;"]
[64151,"'NCAPG'",2,2,0,1.33333333333333,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0000793///condensed chromosome+++GO:0005694///chromosome+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005576///extracellular region+++GO:0072686///mitotic spindle+++GO:0005814///centriole+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0042470///melanosome+++GO:0090543///Flemming body+++GO:0070062///extracellular exosome+++GO:0008290///F-actin capping protein complex+++GO:0000779///condensed chromosome, centromeric region+++GO:0016020///membrane+++GO:0000796///condensin complex+++GO:0005634///nucleus","GO:0051015///actin filament binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0019904///protein domain specific binding+++GO:0044877///protein-containing complex binding+++GO:0003779///actin binding","GO:0071803///positive regulation of podosome assembly+++GO:0051016///barbed-end actin filament capping+++GO:0051693///actin filament capping+++GO:0022617///extracellular matrix disassembly+++GO:0007076///mitotic chromosome condensation+++GO:0007049///cell cycle+++GO:0065003///protein-containing complex assembly+++GO:0051301///cell division+++GO:0030261///chromosome condensation","non-SMC condensin I complex subunit G","[CND3_HUMAN|Reviewed]RecName: Full=Condensin complex subunit 3; AltName: Full=Chromosome-associated protein G; AltName: Full=Condensin subunit CAP-G; Short=hCAP-G; AltName: Full=Melanoma antigen NY-MEL-3; AltName: Full=Non-SMC condensin I complex subunit G; AltName: Full=XCAP-G homolog;+++[B8ZZL6_HUMAN|Unreviewed]SubName: Full=Macrophage-capping protein {ECO:0000313|Ensembl:ENSP00000386596}; Flags: Fragment;+++[D6RA93_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 3 {ECO:0000313|Ensembl:ENSP00000423042};+++[E7ENU9_HUMAN|Unreviewed]SubName: Full=Macrophage-capping protein {ECO:0000313|Ensembl:ENSP00000391923}; Flags: Fragment;+++[H0Y9Z8_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 3 {ECO:0000313|Ensembl:ENSP00000425625}; Flags: Fragment;+++[H7C0X8_HUMAN|Unreviewed]SubName: Full=Macrophage-capping protein {ECO:0000313|Ensembl:ENSP00000397381}; Flags: Fragment;+++[Q6NUR1_HUMAN|Unreviewed]SubName: Full=Non-SMC condensin I complex, subunit G {ECO:0000313|EMBL:AAH68467.1};"]
[64170,"'CARD9'",1,2,0,1,"05152///Tuberculosis+++04625///C-type lectin receptor signaling pathway+++04621///NOD-like receptor signaling pathway","H01109///Chronic mucocutaneous candidiasis (CMC)",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0050700///CARD domain binding+++GO:0042803///protein homodimerization activity","GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0045076///regulation of interleukin-2 biosynthetic process+++GO:0009620///response to fungus+++GO:0032495///response to muramyl dipeptide+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032494///response to peptidoglycan+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0050830///defense response to Gram-positive bacterium+++GO:0045089///positive regulation of innate immune response+++GO:0045087///innate immune response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0042981///regulation of apoptotic process+++GO:0043330///response to exogenous dsRNA+++GO:0051607///defense response to virus+++GO:0046330///positive regulation of JNK cascade+++GO:0042534///regulation of tumor necrosis factor biosynthetic process+++GO:0045408///regulation of interleukin-6 biosynthetic process+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0042493///response to drug+++GO:0002376///immune system process","caspase recruitment domain family member 9","[CARD9_HUMAN|Reviewed]RecName: Full=Caspase recruitment domain-containing protein 9; Short=hCARD9;+++[A0A024R8F1_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 9, isoform CRA_b {ECO:0000313|EMBL:EAW88222.1};+++[A0A024R8I4_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 9, isoform CRA_a {ECO:0000313|EMBL:EAW88224.1};+++[A0A286YFD5_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000493113}; Flags: Fragment;"]
[6425,"'SFRP5'",14026,8293,12615,11644.6666666667,"04310///Wnt signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0017147///Wnt-protein binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0007601///visual perception+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0030111///regulation of Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:0007275///multicellular organism development+++GO:0007163///establishment or maintenance of cell polarity+++GO:0006915///apoptotic process+++GO:0009653///anatomical structure morphogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0030510///regulation of BMP signaling pathway+++GO:2000057///negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis+++GO:0007165///signal transduction+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling","secreted frizzled related protein 5","[SFRP5_HUMAN|Reviewed]RecName: Full=Secreted frizzled-related protein 5; Short=sFRP-5; AltName: Full=Frizzled-related protein 1b; Short=FRP-1b; AltName: Full=Secreted apoptosis-related protein 3; Short=SARP-3; Flags: Precursor;"]
[642623,"'UBTFL1'",0,1,0,0.333333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0003677///DNA binding","GO:0010468///regulation of gene expression+++GO:0007275///multicellular organism development+++GO:0007566///embryo implantation+++GO:0001832///blastocyst growth","upstream binding transcription factor like 1","[UBFL1_HUMAN|Reviewed]RecName: Full=Upstream-binding factor 1-like protein 1 {ECO:0000305};"]
[64288,"'ZSCAN31'",59,61,40,53.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006351///transcription, DNA-templated","zinc finger and SCAN domain containing 31","[ZSC31_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 31; AltName: Full=Zinc finger protein 323;+++[A0A024RCL4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 323, isoform CRA_a {ECO:0000313|EMBL:EAX03156.1};+++[B3KTA4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ37942 fis, clone CTONG2008595, highly similar to Zinc finger protein 323 {ECO:0000313|EMBL:BAG53016.1};+++[Q96QL1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 323 {ECO:0000313|EMBL:AAH08490.1};"]
[643246,"'MAP1LC3B2'",12.7,7.94,3.72,8.12,"04137///Mitophagy - animal+++04216///Ferroptosis+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0000421///autophagosome membrane","GO:0008017///microtubule binding","GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006995///cellular response to nitrogen starvation+++GO:0006914///autophagy","microtubule associated protein 1 light chain 3 beta 2","[MP3B2_HUMAN|Reviewed]RecName: Full=Microtubule-associated proteins 1A/1B light chain 3 beta 2; AltName: Full=Microtubule-associated proteins 1A/1B light chain 3B-like; Flags: Precursor;"]
[64359,"'NXN'",1684.66,1607.25,1801.85,1697.92,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005623///cell+++GO:0005737///cytoplasm","GO:0047134///protein-disulfide reductase activity+++GO:0004791///thioredoxin-disulfide reductase activity+++GO:0016491///oxidoreductase activity","GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0016055///Wnt signaling pathway+++GO:0045454///cell redox homeostasis+++GO:0007275///multicellular organism development+++GO:0031397///negative regulation of protein ubiquitination+++GO:0098869///cellular oxidant detoxification+++GO:0055114///oxidation-reduction process+++GO:0072358///cardiovascular system development","nucleoredoxin","[NXN_HUMAN|Reviewed]RecName: Full=Nucleoredoxin; EC=1.8.1.8;+++[A0A0C4DGI2_HUMAN|Unreviewed]SubName: Full=Nucleoredoxin {ECO:0000313|Ensembl:ENSP00000446446};+++[A0A0G2JQK5_HUMAN|Unreviewed]SubName: Full=Nucleoredoxin {ECO:0000313|Ensembl:ENSP00000485936}; Flags: Fragment;+++[I3L4V6_HUMAN|Unreviewed]SubName: Full=Nucleoredoxin {ECO:0000313|Ensembl:ENSP00000461562}; Flags: Fragment;"]
[64388,"'GREM2'",17,15,4,12,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0008201///heparin binding+++GO:0042803///protein homodimerization activity+++GO:0005125///cytokine activity+++GO:0036122///BMP binding+++GO:0042802///identical protein binding","GO:0048263///determination of dorsal identity+++GO:0060300///regulation of cytokine activity+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0010172///embryonic body morphogenesis+++GO:0030509///BMP signaling pathway+++GO:0038098///sequestering of BMP from receptor via BMP binding+++GO:0007275///multicellular organism development","gremlin 2, DAN family BMP antagonist","[GREM2_HUMAN|Reviewed]RecName: Full=Gremlin-2; AltName: Full=Cysteine knot superfamily 1, BMP antagonist 2; AltName: Full=DAN domain family member 3; AltName: Full=Protein related to DAN and cerberus; Flags: Precursor;+++[A0A024R3Y1_HUMAN|Unreviewed]RecName: Full=Gremlin {ECO:0000256|PIRNR:PIRNR037254};"]
[64405,"'CDH22'",3,0,0,1,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005913///cell-cell adherens junction+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex","GO:0042803///protein homodimerization activity+++GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0046872///metal ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0007420///brain development+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034332///adherens junction organization+++GO:0098609///cell-cell adhesion","cadherin 22","[CAD22_HUMAN|Reviewed]RecName: Full=Cadherin-22; AltName: Full=Pituitary and brain cadherin; Short=PB-cadherin; Flags: Precursor;+++[A8K0L9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76999, highly similar to Homo sapiens cadherin-like 22 (CDH22), mRNA {ECO:0000313|EMBL:BAF82273.1};+++[Q49AS4_HUMAN|Unreviewed]SubName: Full=CDH22 protein {ECO:0000313|EMBL:AAH31232.1};"]
[64420,"'SUSD1'",786,973,933,897.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding",null,"sushi domain containing 1","[SUSD1_HUMAN|Reviewed]RecName: Full=Sushi domain-containing protein 1; Flags: Precursor;+++[F8WAQ1_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000363381};+++[H0Y6B2_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000404269}; Flags: Fragment;+++[H0YCH6_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000431590}; Flags: Fragment;+++[H3BLV4_HUMAN|Unreviewed]SubName: Full=Sushi domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000347558}; Flags: Fragment;"]
[6445,"'SGCG'",86,60,72,72.6666666666667,"05416///Viral myocarditis+++05410///Hypertrophic cardiomyopathy (HCM)+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++05414///Dilated cardiomyopathy (DCM)","H00565///Sarcoglycanopathies+++H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0034774///secretory granule lumen+++GO:0031410///cytoplasmic vesicle+++GO:0016011///dystroglycan complex+++GO:0042383///sarcolemma+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0030658///transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0016012///sarcoglycan complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0043687///post-translational protein modification+++GO:0044267///cellular protein metabolic process+++GO:0002576///platelet degranulation+++GO:0060047///heart contraction+++GO:0007517///muscle organ development","sarcoglycan gamma","[SGCG_HUMAN|Reviewed]RecName: Full=Gamma-sarcoglycan; Short=Gamma-SG; AltName: Full=35 kDa dystrophin-associated glycoprotein; Short=35DAG;"]
[645027,"'EVPLL'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0001533///cornified envelope+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005882///intermediate filament","GO:0005198///structural molecule activity+++GO:0019215///intermediate filament binding+++GO:0030674///protein binding, bridging","GO:0008544///epidermis development+++GO:0042060///wound healing+++GO:0045104///intermediate filament cytoskeleton organization","envoplakin like","[EVPLL_HUMAN|Reviewed]RecName: Full=Envoplakin-like protein;"]
[6457,"'SH3GL3'",19,22,16,19,"04144///Endocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0001669///acrosomal vesicle+++GO:0005769///early endosome+++GO:0098978///glutamatergic synapse+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0099092///postsynaptic density, intracellular component+++GO:0045202///synapse+++GO:0005737///cytoplasm+++GO:0098793///presynapse+++GO:0098845///postsynaptic endosome","GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding","GO:0006897///endocytosis+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:1900186///negative regulation of clathrin-dependent endocytosis+++GO:0007417///central nervous system development+++GO:0007165///signal transduction+++GO:0045666///positive regulation of neuron differentiation","SH3 domain containing GRB2 like 3, endophilin A3","[SH3G3_HUMAN|Reviewed]RecName: Full=Endophilin-A3; AltName: Full=EEN-B2; AltName: Full=Endophilin-3; AltName: Full=SH3 domain protein 2C; AltName: Full=SH3 domain-containing GRB2-like protein 3;+++[A0A024R215_HUMAN|Unreviewed]SubName: Full=SH3-domain GRB2-like 3, isoform CRA_b {ECO:0000313|EMBL:EAW62421.1};+++[H3BRH8_HUMAN|Unreviewed]SubName: Full=Endophilin-A3 {ECO:0000313|Ensembl:ENSP00000456249};+++[Q8IVP1_HUMAN|Unreviewed]SubName: Full=SH3-domain GRB2-like 3, isoform CRA_a {ECO:0000313|EMBL:EAW62419.1}; SubName: Full=SH3GL3 protein {ECO:0000313|EMBL:AAH42864.1};"]
[646588,"'LOC646588'",28,32,22,27.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus+++GO:0010494///cytoplasmic stress granule","GO:0003964///RNA-directed DNA polymerase activity+++GO:0051213///dioxygenase activity+++GO:0000166///nucleotide binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003727///single-stranded RNA binding+++GO:0003697///single-stranded DNA binding+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0042802///identical protein binding","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0010468///regulation of gene expression","uncharacterized LOC646588","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF1_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein {ECO:0000305}; Short=L1-ORF1p {ECO:0000303|PubMed:28806172}; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1; AltName: Full=Transposase element L1Md-A101/L1Md-A102/L1Md-A2;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PO22_POPJA|diamond]RecName: Full=Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2; AltName: Full=Retrovirus-related Pol polyprotein from type I retrotransposable element R2; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; Flags: Fragment;+++[POLR_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from type-2 retrotransposable element R2DM; AltName: Full=Retrovirus-related Pol polyprotein from type II retrotransposable element R2DM; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[646962,"'HRCT1'",14,21,20,18.3333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"histidine rich carboxyl terminus 1","[HRCT1_HUMAN|Reviewed]RecName: Full=Histidine-rich carboxyl terminus protein 1;"]
[64744,"'SMAP2'",544,406,517,489,"04144///Endocytosis",{"$nulls":3},"GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0005096///GTPase activator activity",null,"small ArfGAP2","[SMAP2_HUMAN|Reviewed]RecName: Full=Stromal membrane-associated protein 2; AltName: Full=Stromal membrane-associated protein 1-like;+++[A0A087WV97_HUMAN|Unreviewed]SubName: Full=Stromal membrane-associated protein 2 {ECO:0000313|Ensembl:ENSP00000479285};+++[X6RCC3_HUMAN|Unreviewed]SubName: Full=Stromal membrane-associated protein 2 {ECO:0000313|Ensembl:ENSP00000389895}; Flags: Fragment;"]
[64760,"'FAM160B2'",1695,1706,1668,1689.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"family with sequence similarity 160 member B2","[F16B2_HUMAN|Reviewed]RecName: Full=Protein FAM160B2; AltName: Full=Retinoic acid-induced protein 16;+++[F2Z2X3_HUMAN|Unreviewed]SubName: Full=Protein FAM160B2 {ECO:0000313|Ensembl:ENSP00000395477};"]
[64783,"'RBM15'",64,64,50,59.3333333333333,{"$nulls":4},"GO:0017053///transcriptional repressor complex+++GO:0016607///nuclear speck+++GO:0005635///nuclear envelope+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0036396///RNA N6-methyladenosine methyltransferase complex+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm","GO:0003714///transcription corepressor activity+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003677///DNA binding+++GO:0003729///mRNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0050769///positive regulation of neurogenesis+++GO:0016032///viral process+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0060412///ventricular septum morphogenesis+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0060674///placenta blood vessel development+++GO:0001510///RNA methylation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0048536///spleen development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001569///branching involved in blood vessel morphogenesis","RNA binding motif protein 15","[RBM15_HUMAN|Reviewed]RecName: Full=RNA-binding protein 15 {ECO:0000305}; AltName: Full=One-twenty two protein 1 {ECO:0000303|PubMed:16129689}; AltName: Full=RNA-binding motif protein 15 {ECO:0000303|PubMed:11431691};+++[A0A087WWP4_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 15 {ECO:0000313|Ensembl:ENSP00000480399};+++[F6WRY4_HUMAN|Unreviewed]SubName: Full=Msx2-interacting protein {ECO:0000313|Ensembl:ENSP00000388021}; Flags: Fragment;+++[H0Y5U7_HUMAN|Unreviewed]SubName: Full=Msx2-interacting protein {ECO:0000313|Ensembl:ENSP00000400914}; Flags: Fragment;"]
[64795,"'RMND5A'",658,540,447,548.333333333333,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0034657///GID complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination","required for meiotic nuclear division 5 homolog A","[RMD5A_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein transferase RMND5A; EC=2.3.2.27 {ECO:0000269|PubMed:29911972}; AltName: Full=P44CTLH {ECO:0000303|PubMed:17467196}; AltName: Full=Protein RMD5 homolog A;"]
[64852,"'TUT1'",288,336,327,317,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0050265///RNA uridylyltransferase activity+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0016779///nucleotidyltransferase activity+++GO:0019899///enzyme binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0004652///polynucleotide adenylyltransferase activity","GO:0098789///pre-mRNA cleavage required for polyadenylation+++GO:0006397///mRNA processing+++GO:0071044///histone mRNA catabolic process+++GO:0016180///snRNA processing+++GO:0006378///mRNA polyadenylation","terminal uridylyl transferase 1, U6 snRNA-specific","[STPAP_HUMAN|Reviewed]RecName: Full=Speckle targeted PIP5K1A-regulated poly(A) polymerase; Short=Star-PAP; EC=2.7.7.19; AltName: Full=RNA-binding motif protein 21; Short=RNA-binding protein 21; AltName: Full=U6 snRNA-specific terminal uridylyltransferase 1; Short=U6-TUTase; EC=2.7.7.52;+++[A0A0A8K9B1_HUMAN|Unreviewed]SubName: Full=Up-regulated in lung cancer 6 {ECO:0000313|EMBL:BAQ19752.1};+++[A0A0S2Z5L2_HUMAN|Unreviewed]SubName: Full=Terminal uridylyl transferase 1 U6 snRNA-specific isoform 1 {ECO:0000313|EMBL:ALQ34214.1}; Flags: Fragment;+++[A0A0S2Z5Y5_HUMAN|Unreviewed]SubName: Full=Terminal uridylyl transferase 1 U6 snRNA-specific isoform 2 {ECO:0000313|EMBL:ALQ34215.1}; Flags: Fragment;+++[C9JBX0_HUMAN|Unreviewed]SubName: Full=Speckle targeted PIP5K1A-regulated poly(A) polymerase {ECO:0000313|Ensembl:ENSP00000420739}; Flags: Fragment;+++[F5H0R1_HUMAN|Unreviewed]SubName: Full=Speckle targeted PIP5K1A-regulated poly(A) polymerase {ECO:0000313|Ensembl:ENSP00000308000};+++[F8WA97_HUMAN|Unreviewed]SubName: Full=Speckle targeted PIP5K1A-regulated poly(A) polymerase {ECO:0000313|Ensembl:ENSP00000419792};+++[J3KN81_HUMAN|Unreviewed]SubName: Full=Speckle targeted PIP5K1A-regulated poly(A) polymerase {ECO:0000313|Ensembl:ENSP00000278279}; Flags: Fragment;"]
[64863,"'METTL4'",92,58,60,70,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0009007///site-specific DNA-methyltransferase (adenine-specific) activity+++GO:0008168///methyltransferase activity","GO:0032775///DNA methylation on adenine+++GO:0032259///methylation","methyltransferase like 4","[METL4_HUMAN|Reviewed]RecName: Full=Methyltransferase-like protein 4; EC=2.1.1.-;+++[I3L0Y1_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000458415}; Flags: Fragment;+++[I3L3W2_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000460774}; Flags: Fragment;+++[I3L4A0_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000461097}; Flags: Fragment;+++[I6L9E3_HUMAN|Unreviewed]SubName: Full=METTL4 protein {ECO:0000313|EMBL:AAH56270.2}; Flags: Fragment;+++[J3KNJ7_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000320349};+++[L8EB52_HUMAN|Unreviewed]SubName: Full=Alternative protein METTL4 {ECO:0000313|EMBL:CCQ43698.1};+++[V9GYU3_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000477089}; Flags: Fragment;"]
[64897,"'C12orf43'",278,317,313,302.666666666667,{"$nulls":4},"GO:0005635///nuclear envelope",null,"GO:0016055///Wnt signaling pathway","chromosome 12 open reading frame 43","[CSTOS_HUMAN|Reviewed]RecName: Full=Protein CUSTOS {ECO:0000250|UniProtKB:A9C3N6};+++[B4DRA4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58610 {ECO:0000313|EMBL:BAG61216.1};+++[B4DWJ9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52172 {ECO:0000313|EMBL:BAG63061.1};+++[E7ENF1_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 43 {ECO:0000313|Ensembl:ENSP00000409788};+++[F5H3K2_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 43 {ECO:0000313|Ensembl:ENSP00000438856}; Flags: Fragment;+++[F5H7W8_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 43 {ECO:0000313|Ensembl:ENSP00000442224}; SubName: Full=Chromosome 12 open reading frame 43, isoform CRA_a {ECO:0000313|EMBL:EAW98229.1};+++[F5H8B7_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 43 {ECO:0000313|Ensembl:ENSP00000442041}; Flags: Fragment;+++[G5EA44_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 43 {ECO:0000313|Ensembl:ENSP00000437803}; SubName: Full=Chromosome 12 open reading frame 43, isoform CRA_b {ECO:0000313|EMBL:EAW98230.1};+++[H0YGK4_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 43 {ECO:0000313|Ensembl:ENSP00000443642};"]
[64963,"'MRPS11'",858,839,1026,907.666666666667,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00178///Ribosome, bacteria",null,"GO:0005763///mitochondrial small ribosomal subunit+++GO:0005840///ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion","GO:0048027///mRNA 5'-UTR binding+++GO:0070181///small ribosomal subunit rRNA binding+++GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:0000028///ribosomal small subunit assembly+++GO:0070125///mitochondrial translational elongation+++GO:0032543///mitochondrial translation+++GO:0006412///translation+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0070126///mitochondrial translational termination","mitochondrial ribosomal protein S11","[RT11_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S11, mitochondrial; Short=MRP-S11; Short=S11mt; AltName: Full=Cervical cancer proto-oncogene 2 protein; Short=HCC-2; AltName: Full=Mitochondrial small ribosomal subunit protein uS11m {ECO:0000303|PubMed:25838379}; Flags: Precursor;+++[H0YL99_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S11, mitochondrial {ECO:0000313|Ensembl:ENSP00000453116};+++[Q96Q62_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein S11 {ECO:0000313|EMBL:BAB54939.2}; Flags: Fragment;"]
[6498,"'SKIL'",657,715,568,646.666666666667,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0001669///acrosomal vesicle+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0003714///transcription corepressor activity+++GO:0046332///SMAD binding+++GO:0003682///chromatin binding+++GO:0003677///DNA binding","GO:0007283///spermatogenesis+++GO:0070306///lens fiber cell differentiation+++GO:1902231///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0007519///skeletal muscle tissue development+++GO:0002260///lymphocyte homeostasis+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0070207///protein homotrimerization+++GO:0046677///response to antibiotic+++GO:0070848///response to growth factor+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001825///blastocyst formation+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0007050///cell cycle arrest+++GO:0034097///response to cytokine+++GO:0045596///negative regulation of cell differentiation+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0048666///neuron development+++GO:0050772///positive regulation of axonogenesis+++GO:0070208///protein heterotrimerization","SKI like proto-oncogene","[SKIL_HUMAN|Reviewed]RecName: Full=Ski-like protein; AltName: Full=Ski-related oncogene; AltName: Full=Ski-related protein;+++[C9J8R9_HUMAN|Unreviewed]SubName: Full=Ski-like protein {ECO:0000313|Ensembl:ENSP00000417670}; Flags: Fragment;+++[H7C4V3_HUMAN|Unreviewed]SubName: Full=Ski-like protein {ECO:0000313|Ensembl:ENSP00000418237}; Flags: Fragment;+++[I6QMM9_HUMAN|Unreviewed]SubName: Full=Ski-like protein {ECO:0000313|EMBL:AFM38218.1}; Flags: Fragment;"]
[65078,"'RTN4R'",320,283,319,307.333333333333,{"$nulls":4},"GO:0030426///growth cone+++GO:0043005///neuron projection+++GO:0043198///dendritic shaft+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0044295///axonal growth cone+++GO:0031362///anchored component of external side of plasma membrane+++GO:0030424///axon+++GO:0045121///membrane raft+++GO:0042995///cell projection+++GO:0098978///glutamatergic synapse+++GO:0030425///dendrite+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0031225///anchored component of membrane+++GO:0009986///cell surface+++GO:0043204///perikaryon+++GO:0098793///presynapse","GO:0035374///chondroitin sulfate binding+++GO:1905576///ganglioside GT1b binding+++GO:0038023///signaling receptor activity+++GO:1905573///ganglioside GM1 binding+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0038131///neuregulin receptor activity","GO:0030517///negative regulation of axon extension+++GO:0043547///positive regulation of GTPase activity+++GO:0050771///negative regulation of axonogenesis+++GO:0007409///axonogenesis+++GO:0023041///neuronal signal transduction+++GO:0048681///negative regulation of axon regeneration+++GO:0022038///corpus callosum development+++GO:0010977///negative regulation of neuron projection development+++GO:0035025///positive regulation of Rho protein signal transduction+++GO:0007166///cell surface receptor signaling pathway","reticulon 4 receptor","[RTN4R_HUMAN|Reviewed]RecName: Full=Reticulon-4 receptor; AltName: Full=Nogo receptor; Short=NgR; AltName: Full=Nogo-66 receptor; Flags: Precursor;+++[H7C0V4_HUMAN|Unreviewed]SubName: Full=Reticulon-4 receptor {ECO:0000313|Ensembl:ENSP00000396872}; Flags: Fragment;+++[H7C215_HUMAN|Unreviewed]SubName: Full=Reticulon-4 receptor {ECO:0000313|Ensembl:ENSP00000403535}; Flags: Fragment;"]
[6510,"'SLC1A5'",372,409,416,399,"05230///Central carbon metabolism in cancer+++04974///Protein digestion and absorption",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0042470///melanosome+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane","GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding+++GO:0015194///L-serine transmembrane transporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0015186///L-glutamine transmembrane transporter activity+++GO:0001618///virus receptor activity+++GO:0005515///protein binding+++GO:0015171///amino acid transmembrane transporter activity+++GO:0015293///symporter activity","GO:0070207///protein homotrimerization+++GO:0006868///glutamine transport+++GO:1903803///L-glutamine import across plasma membrane+++GO:0006865///amino acid transport+++GO:0015825///L-serine transport+++GO:0010585///glutamine secretion+++GO:0055085///transmembrane transport+++GO:0046718///viral entry into host cell+++GO:0016032///viral process+++GO:0015804///neutral amino acid transport","solute carrier family 1 member 5","[AAAT_HUMAN|Reviewed]RecName: Full=Neutral amino acid transporter B(0); Short=ATB(0); AltName: Full=Baboon M7 virus receptor; AltName: Full=RD114/simian type D retrovirus receptor; AltName: Full=Sodium-dependent neutral amino acid transporter type 2; AltName: Full=Solute carrier family 1 member 5;+++[M0QX44_HUMAN|Unreviewed]RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216}; Flags: Fragment;+++[M0QXM4_HUMAN|Unreviewed]RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};+++[M0R144_HUMAN|Unreviewed]SubName: Full=Neutral amino acid transporter B(0) {ECO:0000313|Ensembl:ENSP00000471626}; Flags: Fragment;+++[Q59ES3_HUMAN|Unreviewed]RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216}; Flags: Fragment;+++[Q71UA6_HUMAN|Unreviewed]RecName: Full=Amino acid transporter {ECO:0000256|RuleBase:RU361216};"]
[65220,"'NADK'",1248,1293,1231,1257.33333333333,"01100///Metabolic pathways+++00760///Nicotinate and nicotinamide metabolism","H01929///2,4-Dienoyl-CoA reductase deficiency+++H00525///Disorders of mitochondrial fatty-acid oxidation",null,"R00104///ATP:NAD+ 2'-phosphotransferase   ATP + NAD+ <=> ADP + NADP+","GO:0005829///cytosol","GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003951///NAD+ kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding","GO:0006741///NADP biosynthetic process+++GO:0019674///NAD metabolic process+++GO:0016310///phosphorylation+++GO:0046034///ATP metabolic process+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus","NAD kinase","[NADK_HUMAN|Reviewed]RecName: Full=NAD kinase; EC=2.7.1.23; AltName: Full=Poly(P)/ATP NAD kinase;+++[A0A024R058_HUMAN|Unreviewed]SubName: Full=NAD kinase, isoform CRA_a {ECO:0000313|EMBL:EAW56155.1};+++[A0A0A0MR98_HUMAN|Unreviewed]SubName: Full=NAD kinase {ECO:0000313|Ensembl:ENSP00000339727};+++[J3KSP9_HUMAN|Unreviewed]SubName: Full=NAD kinase {ECO:0000313|Ensembl:ENSP00000462589}; Flags: Fragment;+++[J3KTI3_HUMAN|Unreviewed]SubName: Full=NAD kinase {ECO:0000313|Ensembl:ENSP00000462999}; Flags: Fragment;+++[J3QR86_HUMAN|Unreviewed]SubName: Full=NAD kinase {ECO:0000313|Ensembl:ENSP00000464096}; Flags: Fragment;+++[J3QRC0_HUMAN|Unreviewed]SubName: Full=NAD kinase {ECO:0000313|Ensembl:ENSP00000464137}; Flags: Fragment;+++[Q6PJ22_HUMAN|Unreviewed]SubName: Full=FLJ13052 protein {ECO:0000313|EMBL:AAH24219.1}; Flags: Fragment;"]
[65263,"'PYCR3'",301,273.03,356.21,310.08,"00330///Arginine and proline metabolism+++01110///Biosynthesis of secondary metabolites+++01230///Biosynthesis of amino acids+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways","H00557///Cutis laxa+++H00679///Hypomyelinating leukodystrophy+++H00558///Geroderma osteodysplasticum","M00015///Proline biosynthesis, glutamate => proline","R03291///trans-4-Hydroxy-L-proline:NAD+ 5-oxidoreductase   Hydroxyproline + NAD+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADH + H++++R01248///L-Proline:NAD+ 5-oxidoreductase   L-Proline + NAD+ <=> (S)-1-Pyrroline-5-carboxylate + NADH + H++++R03293///trans-4-Hydroxy-L-proline:NADP+ 5-oxidoreductase   Hydroxyproline + NADP+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADPH + H++++R01251///L-Proline:NADP+ 5-oxidoreductase   L-Proline + NADP+ <=> (S)-1-Pyrroline-5-carboxylate + NADPH + H+","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0004735///pyrroline-5-carboxylate reductase activity+++GO:0016491///oxidoreductase activity","GO:0006561///proline biosynthetic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0055114///oxidation-reduction process+++GO:0055129///L-proline biosynthetic process","pyrroline-5-carboxylate reductase 3","[P5CR3_HUMAN|Reviewed]RecName: Full=Pyrroline-5-carboxylate reductase 3 {ECO:0000312|HGNC:HGNC:25846}; Short=P5C reductase 3; Short=P5CR 3; EC=1.5.1.2 {ECO:0000269|PubMed:23024808}; AltName: Full=Pyrroline-5-carboxylate reductase-like protein;+++[A0A087WTU2_HUMAN|Unreviewed]SubName: Full=Pyrroline-5-carboxylate reductase 3 {ECO:0000313|Ensembl:ENSP00000478138}; Flags: Fragment;+++[A0A0A0MQS1_HUMAN|Unreviewed]RecName: Full=Pyrroline-5-carboxylate reductase {ECO:0000256|RuleBase:RU003903}; EC=1.5.1.2 {ECO:0000256|RuleBase:RU003903};+++[B4DGI7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57148, highly similar to Homo sapiens pyrroline-5-carboxylate reductase-like (PYCRL), mRNA {ECO:0000313|EMBL:BAG57798.1};+++[B5MD87_HUMAN|Unreviewed]SubName: Full=Pyrroline-5-carboxylate reductase 3 {ECO:0000313|Ensembl:ENSP00000366802};+++[D3DWK4_HUMAN|Unreviewed]RecName: Full=Pyrroline-5-carboxylate reductase {ECO:0000256|RuleBase:RU003903}; EC=1.5.1.2 {ECO:0000256|RuleBase:RU003903};+++[F8WEI0_HUMAN|Unreviewed]SubName: Full=Pyrroline-5-carboxylate reductase 3 {ECO:0000313|Ensembl:ENSP00000401804};"]
[6532,"'SLC6A4'",2,2.57,1.16,1.91,"04726///Serotonergic synapse","H01450///Obsessive-compulsive disorder (OCD)",null,null,"GO:0005737///cytoplasm+++GO:0099055///integral component of postsynaptic membrane+++GO:0045121///membrane raft+++GO:0030425///dendrite+++GO:0099056///integral component of presynaptic membrane+++GO:0043005///neuron projection+++GO:0012505///endomembrane system+++GO:0016021///integral component of membrane+++GO:0005770///late endosome+++GO:0005634///nucleus+++GO:0099523///presynaptic cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0099154///serotonergic synapse+++GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0099524///postsynaptic cytosol+++GO:0016020///membrane+++GO:0005776///autophagosome+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005814///centriole+++GO:0016234///inclusion body+++GO:0005783///endoplasmic reticulum+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0030424///axon+++GO:0032991///protein-containing complex+++GO:0098793///presynapse","GO:0046872///metal ion binding+++GO:0017137///Rab GTPase binding+++GO:0042803///protein homodimerization activity+++GO:0008504///monoamine transmembrane transporter activity+++GO:0050998///nitric-oxide synthase binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0048487///beta-tubulin binding+++GO:0034452///dynactin binding+++GO:0015293///symporter activity+++GO:0002039///p53 binding+++GO:0005335///serotonin:sodium symporter activity+++GO:0044325///ion channel binding+++GO:0045505///dynein intermediate chain binding+++GO:0031072///heat shock protein binding+++GO:0051015///actin filament binding+++GO:0051378///serotonin binding+++GO:0005522///profilin binding+++GO:0005328///neurotransmitter:sodium symporter activity+++GO:0019900///kinase binding+++GO:0017022///myosin binding+++GO:0019811///cocaine binding+++GO:0042802///identical protein binding","GO:0007030///Golgi organization+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0045787///positive regulation of cell cycle+++GO:0032355///response to estradiol+++GO:1905289///regulation of CAMKK-AMPK signaling cascade+++GO:0007613///memory+++GO:0043065///positive regulation of apoptotic process+++GO:0007420///brain development+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0071300///cellular response to retinoic acid+++GO:0000132///establishment of mitotic spindle orientation+++GO:0048854///brain morphogenesis+++GO:0009636///response to toxic substance+++GO:0042136///neurotransmitter biosynthetic process+++GO:1905337///positive regulation of aggrephagy+++GO:0051259///protein complex oligomerization+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0051610///serotonin uptake+++GO:0006915///apoptotic process+++GO:1904504///positive regulation of lipophagy+++GO:0035176///social behavior+++GO:0051260///protein homooligomerization+++GO:0042493///response to drug+++GO:0055085///transmembrane transport+++GO:0006836///neurotransmitter transport+++GO:0001666///response to hypoxia+++GO:0045665///negative regulation of neuron differentiation+++GO:0010628///positive regulation of gene expression+++GO:2000479///regulation of cAMP-dependent protein kinase activity+++GO:0045724///positive regulation of cilium assembly+++GO:0046621///negative regulation of organ growth+++GO:0032227///negative regulation of synaptic transmission, dopaminergic+++GO:0047496///vesicle transport along microtubule+++GO:0014064///positive regulation of serotonin secretion+++GO:0015844///monoamine transport+++GO:0007584///response to nutrient+++GO:0090067///regulation of thalamus size+++GO:0031587///positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity+++GO:0007623///circadian rhythm+++GO:0071310///cellular response to organic substance+++GO:0042310///vasoconstriction+++GO:0031648///protein destabilization+++GO:0010033///response to organic substance+++GO:0071321///cellular response to cGMP+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0042297///vocal learning+++GO:0006837///serotonin transport+++GO:0042713///sperm ejaculation+++GO:0021941///negative regulation of cerebellar granule cell precursor proliferation","solute carrier family 6 member 4","[SC6A4_HUMAN|Reviewed]RecName: Full=Sodium-dependent serotonin transporter; Short=SERT {ECO:0000250|UniProtKB:P31652}; AltName: Full=5HT transporter; Short=5HTT; AltName: Full=Solute carrier family 6 member 4;+++[B2R7Y7_HUMAN|Unreviewed]RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};+++[B3VRQ0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96218.1}; Flags: Fragment;+++[B3VRQ5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96213.1}; Flags: Fragment;+++[B3VRR0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96208.1}; Flags: Fragment;+++[B3VRR5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96203.1}; Flags: Fragment;+++[B3VRS0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96198.1}; Flags: Fragment;+++[B3VRS5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96193.1}; Flags: Fragment;+++[B3VRT5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96183.1}; Flags: Fragment;+++[B3VRU0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96178.1}; Flags: Fragment;+++[B3VRU5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96173.1}; Flags: Fragment;+++[B3VRV0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96168.1}; Flags: Fragment;+++[B3VRV5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96163.1}; Flags: Fragment;+++[B3VRW0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96158.1}; Flags: Fragment;+++[H0YA07_HUMAN|Unreviewed]SubName: Full=Huntingtin {ECO:0000313|Ensembl:ENSP00000425743}; Flags: Fragment;+++[J3KPR9_HUMAN|Unreviewed]RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732}; Flags: Fragment;+++[J3QKP3_HUMAN|Unreviewed]SubName: Full=Sodium-dependent serotonin transporter {ECO:0000313|Ensembl:ENSP00000463172}; Flags: Fragment;+++[Q9NYN7_HUMAN|Unreviewed]SubName: Full=Serotonin transporter {ECO:0000313|EMBL:AAF61945.1}; SubName: Full=Solute carrier family 6 member 4 {ECO:0000313|EMBL:ACE96188.1}; Flags: Fragment;+++[X5DPA1_HUMAN|Unreviewed]SubName: Full=Huntingtin isoform A {ECO:0000313|EMBL:AHW56711.1};"]
[653499,"'LGALS7B'",0,0,1,0.333333333333333,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0030246///carbohydrate binding","GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0006915///apoptotic process","galectin 7B","[LEG7_HUMAN|Reviewed]RecName: Full=Galectin-7; Short=Gal-7; AltName: Full=HKL-14; AltName: Full=PI7; AltName: Full=p53-induced gene 1 protein;+++[M0R281_HUMAN|Unreviewed]SubName: Full=Galectin-7 {ECO:0000313|Ensembl:ENSP00000472380}; Flags: Fragment;"]
[6540,"'SLC6A13'",2809,1587,2231,2209,null,"H00480///Non-syndromic X-linked mental retardation+++H00849///Creatine deficiency syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane","GO:0042165///neurotransmitter binding+++GO:0005328///neurotransmitter:sodium symporter activity+++GO:0015293///symporter activity+++GO:0005332///gamma-aminobutyric acid:sodium symporter activity","GO:0015812///gamma-aminobutyric acid transport+++GO:0006836///neurotransmitter transport+++GO:0055085///transmembrane transport","solute carrier family 6 member 13","[S6A13_HUMAN|Reviewed]RecName: Full=Sodium- and chloride-dependent GABA transporter 2; Short=GAT-2; AltName: Full=Solute carrier family 6 member 13;+++[F5GZA5_HUMAN|Unreviewed]SubName: Full=Sodium- and chloride-dependent GABA transporter 2 {ECO:0000313|Ensembl:ENSP00000444606}; Flags: Fragment;+++[F5H5D9_HUMAN|Unreviewed]SubName: Full=Sodium- and chloride-dependent GABA transporter 2 {ECO:0000313|Ensembl:ENSP00000443466};+++[F5H6S9_HUMAN|Unreviewed]RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};"]
[6549,"'SLC9A2'",12,6,6,8,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0015299///solute:proton antiporter activity+++GO:0015297///antiporter activity+++GO:0015386///potassium:proton antiporter activity+++GO:0015385///sodium:proton antiporter activity","GO:0098719///sodium ion import across plasma membrane+++GO:0051453///regulation of intracellular pH+++GO:0006814///sodium ion transport+++GO:0006811///ion transport+++GO:1902600///proton transmembrane transport+++GO:0008104///protein localization+++GO:0006885///regulation of pH+++GO:0071805///potassium ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0006812///cation transport","solute carrier family 9 member A2","[SL9A2_HUMAN|Reviewed]RecName: Full=Sodium/hydrogen exchanger 2; AltName: Full=Na(+)/H(+) exchanger 2; Short=NHE-2; AltName: Full=Solute carrier family 9 member 2;"]
[6572,"'SLC18A3'",336,151,279,255.333333333333,"04721///Synaptic vesicle cycle+++04725///Cholinergic synapse","H00770///Congenital myasthenic syndrome",null,null,"GO:0030665///clathrin-coated vesicle membrane+++GO:0016021///integral component of membrane+++GO:0060201///clathrin-sculpted acetylcholine transport vesicle membrane+++GO:0043195///terminal bouton+++GO:0030121///AP-1 adaptor complex+++GO:0030122///AP-2 adaptor complex+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005277///acetylcholine transmembrane transporter activity","GO:0007269///neurotransmitter secretion+++GO:0006855///drug transmembrane transport+++GO:0072488///ammonium transmembrane transport+++GO:0006836///neurotransmitter transport+++GO:0061024///membrane organization+++GO:1901374///acetate ester transport+++GO:0015695///organic cation transport+++GO:0055085///transmembrane transport","solute carrier family 18 member A3","[VACHT_HUMAN|Reviewed]RecName: Full=Vesicular acetylcholine transporter; Short=VAChT; AltName: Full=Solute carrier family 18 member 3;"]
[6590,"'SLPI'",13,40,43,32,{"$nulls":4},"GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0035580///specific granule lumen+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016853///isomerase activity+++GO:0003677///DNA binding+++GO:0004866///endopeptidase inhibitor activity+++GO:0003729///mRNA binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0008233///peptidase activity+++GO:0030414///peptidase inhibitor activity+++GO:0019899///enzyme binding+++GO:0004476///mannose-6-phosphate isomerase activity","GO:0009298///GDP-mannose biosynthetic process+++GO:0019731///antibacterial humoral response+++GO:0002376///immune system process+++GO:0045071///negative regulation of viral genome replication+++GO:0042742///defense response to bacterium+++GO:0010951///negative regulation of endopeptidase activity+++GO:0000032///cell wall mannoprotein biosynthetic process+++GO:0061611///mannose to fructose-6-phosphate metabolic process+++GO:0010466///negative regulation of peptidase activity+++GO:0006486///protein glycosylation+++GO:0045087///innate immune response+++GO:0032091///negative regulation of protein binding+++GO:0043312///neutrophil degranulation+++GO:0006955///immune response+++GO:0006508///proteolysis+++GO:0032496///response to lipopolysaccharide+++GO:0005975///carbohydrate metabolic process","secretory leukocyte peptidase inhibitor","[SLPI_HUMAN|Reviewed]RecName: Full=Antileukoproteinase; Short=ALP; AltName: Full=BLPI; AltName: Full=HUSI-1 {ECO:0000303|PubMed:3485543, ECO:0000303|PubMed:3533531}; AltName: Full=Mucus proteinase inhibitor; Short=MPI; AltName: Full=Protease inhibitor WAP4; AltName: Full=Secretory leukocyte protease inhibitor {ECO:0000303|PubMed:3462719}; AltName: Full=Seminal proteinase inhibitor; AltName: Full=WAP four-disulfide core domain protein 4; Flags: Precursor;+++[B4DYB8_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000454312}; SubName: Full=cDNA FLJ54812, moderately similar to Mannose-6-phosphate isomerase {ECO:0000313|EMBL:BAG63680.1};+++[H3BM77_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000454267};+++[H3BMZ9_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000454619};+++[H3BN01_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000454622}; Flags: Fragment;+++[H3BNY8_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000455065}; Flags: Fragment;+++[H3BP57_HUMAN|Unreviewed]RecName: Full=Mannose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000611}; EC=5.3.1.8 {ECO:0000256|RuleBase:RU000611}; Flags: Fragment;+++[H3BPM5_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000455383}; Flags: Fragment;+++[H3BPU7_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000455477}; Flags: Fragment;+++[H3BQX0_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000455972}; Flags: Fragment;+++[H3BT46_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000457013}; Flags: Fragment;+++[H3BT48_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000457020};+++[H3BU66_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000457494}; Flags: Fragment;+++[H3BUG1_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000457619}; Flags: Fragment;+++[H3BUZ9_HUMAN|Unreviewed]SubName: Full=Mannose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000457885};+++[Q6LDI0_HUMAN|Unreviewed]SubName: Full=Secretory leukoprotease inhibitor protein {ECO:0000313|EMBL:AAA60559.1}; Flags: Fragment;"]
[65987,"'KCTD14'",10.11,16.99,30.94,19.3466666666667,null,"H00810///Progressive myoclonic epilepsy (PME/ EPM)",{"$nulls":3},"GO:0005515///protein binding","GO:0051260///protein homooligomerization","potassium channel tetramerization domain containing 14","[KCD14_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing protein KCTD14;"]
[66008,"'TRAK2'",1094,1212,835,1047,"04727///GABAergic synapse+++01100///Metabolic pathways",{"$nulls":3},"GO:0005769///early endosome+++GO:0032839///dendrite cytoplasm+++GO:1904115///axon cytoplasm+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0043005///neuron projection+++GO:0005739///mitochondrion+++GO:0043025///neuronal cell body+++GO:0030425///dendrite+++GO:0044295///axonal growth cone+++GO:0005768///endosome+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle","GO:0050811///GABA receptor binding+++GO:0030911///TPR domain binding+++GO:0017022///myosin binding+++GO:0019899///enzyme binding+++GO:0005102///signaling receptor binding+++GO:0019894///kinesin binding+++GO:0005515///protein binding","GO:0008104///protein localization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006605///protein targeting+++GO:0098957///anterograde axonal transport of mitochondrion+++GO:0008089///anterograde axonal transport+++GO:0048311///mitochondrion distribution+++GO:0008333///endosome to lysosome transport+++GO:0047496///vesicle transport along microtubule+++GO:0022008///neurogenesis+++GO:0006493///protein O-linked glycosylation+++GO:0048813///dendrite morphogenesis+++GO:0098972///anterograde dendritic transport of mitochondrion+++GO:0098939///dendritic transport of mitochondrion+++GO:0050771///negative regulation of axonogenesis","trafficking kinesin protein 2","[TRAK2_HUMAN|Reviewed]RecName: Full=Trafficking kinesin-binding protein 2; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein;+++[Q53RS6_HUMAN|Unreviewed]SubName: Full=Trafficking kinesin-binding protein 2 {ECO:0000313|Ensembl:ENSP00000388254}; Flags: Fragment;+++[Q8IU62_HUMAN|Unreviewed]SubName: Full=Trafficking protein, kinesin binding 2 {ECO:0000313|EMBL:AAH40668.1};"]
[6601,"'SMARCC2'",2338,2593,2243,2391.33333333333,"04714///Thermogenesis+++05225///Hepatocellular carcinoma",{"$nulls":3},"GO:0005634///nucleus+++GO:0071565///nBAF complex+++GO:0071564///npBAF complex+++GO:0000790///nuclear chromatin+++GO:0016514///SWI/SNF complex+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006325///chromatin organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006338///chromatin remodeling+++GO:0021882///regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006337///nucleosome disassembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0000122///negative regulation of transcription by RNA polymerase II","SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2","[SMRC2_HUMAN|Reviewed]RecName: Full=SWI/SNF complex subunit SMARCC2; AltName: Full=BRG1-associated factor 170; Short=BAF170; AltName: Full=SWI/SNF complex 170 kDa subunit; AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2;+++[A0A024RB22_HUMAN|Unreviewed]SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2, isoform CRA_a {ECO:0000313|EMBL:EAW96907.1};+++[F8VXC8_HUMAN|Unreviewed]SubName: Full=SWI/SNF complex subunit SMARCC2 {ECO:0000313|Ensembl:ENSP00000449396};+++[F8VZW6_HUMAN|Unreviewed]SubName: Full=SWI/SNF complex subunit SMARCC2 {ECO:0000313|Ensembl:ENSP00000447680};"]
[6614,"'SIGLEC1'",24,21,18,21,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region","GO:0030246///carbohydrate binding","GO:0006954///inflammatory response+++GO:0006897///endocytosis+++GO:0007160///cell-matrix adhesion+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion","sialic acid binding Ig like lectin 1","[SN_HUMAN|Reviewed]RecName: Full=Sialoadhesin; AltName: Full=Sialic acid-binding Ig-like lectin 1; Short=Siglec-1; AltName: CD_antigen=CD169; Flags: Precursor;+++[A5D8Z7_HUMAN|Unreviewed]SubName: Full=SIGLEC1 protein {ECO:0000313|EMBL:AAI41885.1}; Flags: Fragment;+++[H7C0M6_HUMAN|Unreviewed]SubName: Full=Sialoadhesin {ECO:0000313|Ensembl:ENSP00000395778}; Flags: Fragment;"]
[663,"'BNIP2'",444,436,361,413.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031616///spindle pole centrosome+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005814///centriole","GO:0005096///GTPase activator activity+++GO:0004309///exopolyphosphatase activity+++GO:0005515///protein binding+++GO:0005509///calcium ion binding","GO:0043410///positive regulation of MAPK cascade+++GO:0045666///positive regulation of neuron differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0006798///polyphosphate catabolic process+++GO:0001824///blastocyst development+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051146///striated muscle cell differentiation+++GO:0007098///centrosome cycle+++GO:0006915///apoptotic process","BCL2 interacting protein 2","[BNIP2_HUMAN|Reviewed]RecName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2;+++[H7C096_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000393644}; Flags: Fragment;+++[H7C142_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000398364}; Flags: Fragment;+++[J3KN59_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000267859};"]
[6645,"'SNTB2'",382,353,347,360.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030658///transport vesicle membrane+++GO:0005874///microtubule+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0045202///synapse+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0005856///cytoskeleton","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0005198///structural molecule activity+++GO:0005516///calmodulin binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome","syntrophin beta 2","[SNTB2_HUMAN|Reviewed]RecName: Full=Beta-2-syntrophin; AltName: Full=59 kDa dystrophin-associated protein A1 basic component 2; AltName: Full=Syntrophin-3; Short=SNT3; AltName: Full=Syntrophin-like; Short=SNTL;+++[A0A024R732_HUMAN|Unreviewed]SubName: Full=Syntrophin, beta 2 (Dystrophin-associated protein A1, 59kDa, basic component 2), isoform CRA_a {ECO:0000313|EMBL:EAW83260.1};+++[A0A0G2JLB8_HUMAN|Unreviewed]SubName: Full=Beta-2-syntrophin {ECO:0000313|Ensembl:ENSP00000458573}; Flags: Fragment;+++[A0A0G2JM75_HUMAN|Unreviewed]SubName: Full=Beta-2-syntrophin {ECO:0000313|Ensembl:ENSP00000478662}; Flags: Fragment;+++[A0A140TA73_HUMAN|Unreviewed]SubName: Full=Beta-2-syntrophin {ECO:0000313|Ensembl:ENSP00000461506}; Flags: Fragment;+++[H0YCS0_HUMAN|Unreviewed]SubName: Full=Beta-2-syntrophin {ECO:0000313|Ensembl:ENSP00000432201}; Flags: Fragment;+++[H7BY41_HUMAN|Unreviewed]SubName: Full=Beta-2-syntrophin {ECO:0000313|Ensembl:ENSP00000353686}; Flags: Fragment;+++[J3KT21_HUMAN|Unreviewed]SubName: Full=Beta-2-syntrophin {ECO:0000313|Ensembl:ENSP00000462765}; Flags: Fragment;+++[L8EAJ4_HUMAN|Unreviewed]SubName: Full=Alternative protein SNTB2 {ECO:0000313|EMBL:CCQ43373.1};"]
[6664,"'SOX11'",505,696,575,592,null,"H00773///Autosomal dominant mental retardation",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0044798///nuclear transcription factor complex","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008135///translation factor activity, RNA binding+++GO:0001158///enhancer sequence-specific DNA binding","GO:0045669///positive regulation of osteoblast differentiation+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0060023///soft palate development+++GO:0008283///cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0014003///oligodendrocyte development+++GO:0003151///outflow tract morphogenesis+++GO:0072395///signal transduction involved in cell cycle checkpoint+++GO:0061029///eyelid development in camera-type eye+++GO:0030154///cell differentiation+++GO:0060022///hard palate development+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0060548///negative regulation of cell death+++GO:0061386///closure of optic fissure+++GO:0001841///neural tube formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030182///neuron differentiation+++GO:0060563///neuroepithelial cell differentiation+++GO:0045778///positive regulation of ossification+++GO:0048557///embryonic digestive tract morphogenesis+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0050672///negative regulation of lymphocyte proliferation+++GO:2000648///positive regulation of stem cell proliferation+++GO:0061303///cornea development in camera-type eye+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045666///positive regulation of neuron differentiation+++GO:0003357///noradrenergic neuron differentiation+++GO:0061053///somite development+++GO:0035332///positive regulation of hippo signaling+++GO:0003211///cardiac ventricle formation+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0060253///negative regulation of glial cell proliferation+++GO:0046887///positive regulation of hormone secretion+++GO:0007275///multicellular organism development+++GO:0050769///positive regulation of neurogenesis+++GO:0006412///translation+++GO:0008284///positive regulation of cell proliferation+++GO:0021782///glial cell development+++GO:0014009///glial cell proliferation+++GO:0060425///lung morphogenesis+++GO:0001822///kidney development+++GO:0048485///sympathetic nervous system development+++GO:0014032///neural crest cell development+++GO:0010629///negative regulation of gene expression+++GO:0060412///ventricular septum morphogenesis+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:0021510///spinal cord development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0001501///skeletal system development+++GO:0035914///skeletal muscle cell differentiation+++GO:0060174///limb bud formation+++GO:2001111///positive regulation of lens epithelial cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated","SRY-box 11","[SOX11_HUMAN|Reviewed]RecName: Full=Transcription factor SOX-11;+++[L8E7T1_HUMAN|Unreviewed]SubName: Full=Alternative protein SOX11 {ECO:0000313|EMBL:CCQ43199.1};+++[Q05CH0_HUMAN|Unreviewed]SubName: Full=SOX11 protein {ECO:0000313|EMBL:AAH25789.1}; Flags: Fragment;"]
[668,"'FOXL2'",5,5,5,5,null,"H00826///Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES)+++H00627///Premature ovarian failure",null,null,"GO:0005654///nucleoplasm+++GO:0045171///intercellular bridge+++GO:0005634///nucleus","GO:0030331///estrogen receptor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043028///cysteine-type endopeptidase regulator activity involved in apoptotic process+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0043565///sequence-specific DNA binding","GO:0043065///positive regulation of apoptotic process+++GO:0008585///female gonad development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060014///granulosa cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007338///single fertilization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006309///apoptotic DNA fragmentation+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002074///extraocular skeletal muscle development+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0009653///anatomical structure morphogenesis+++GO:0060065///uterus development+++GO:0001541///ovarian follicle development+++GO:0019101///female somatic sex determination+++GO:0033686///positive regulation of luteinizing hormone secretion+++GO:0001555///oocyte growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048048///embryonic eye morphogenesis","forkhead box L2","[FOXL2_HUMAN|Reviewed]RecName: Full=Forkhead box protein L2;+++[Q05CX9_HUMAN|Unreviewed]SubName: Full=FOXL2 protein {ECO:0000313|EMBL:AAH19896.1}; Flags: Fragment;+++[Q4JHB5_HUMAN|Unreviewed]SubName: Full=Transcription factor FOXL2 mutant 3 {ECO:0000313|EMBL:AAY89236.1};+++[Q4JHB6_HUMAN|Unreviewed]SubName: Full=Transcription factor FOXL2 mutant 2 {ECO:0000313|EMBL:AAY89235.1};+++[Q4JHB7_HUMAN|Unreviewed]SubName: Full=Transcription factor FOXL2 mutant 1 {ECO:0000313|EMBL:AAY89234.1};+++[Q53ZD3_HUMAN|Unreviewed]SubName: Full=FOXL2 {ECO:0000313|EMBL:AAY21821.1}; SubName: Full=Forkhead box L2 {ECO:0000313|EMBL:AAQ01519.1};"]
[6713,"'SQLE'",1466,1677,1567,1570,"01130///Biosynthesis of antibiotics+++00909///Sesquiterpenoid and triterpenoid biosynthesis+++00100///Steroid biosynthesis+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites",null,null,"R02874///squalene,NADPH-hemoprotein:oxygen oxidoreductase (2,3-epoxidizing)   Squalene + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> (S)-2,3-Epoxysqualene + [Oxidized NADPH---hemoprotein reductase] + H2O","GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0031090///organelle membrane","GO:0004506///squalene monooxygenase activity+++GO:0071949///FAD binding+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding","GO:0045540///regulation of cholesterol biosynthetic process+++GO:0010033///response to organic substance+++GO:0006725///cellular aromatic compound metabolic process+++GO:0055114///oxidation-reduction process+++GO:0016126///sterol biosynthetic process+++GO:0006695///cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process","squalene epoxidase","[ERG1_HUMAN|Reviewed]RecName: Full=Squalene monooxygenase; EC=1.14.14.17; AltName: Full=Squalene epoxidase; Short=SE;+++[E5RJH9_HUMAN|Unreviewed]SubName: Full=Squalene monooxygenase {ECO:0000313|Ensembl:ENSP00000428239}; Flags: Fragment;+++[E7EVQ6_HUMAN|Unreviewed]SubName: Full=Squalene monooxygenase {ECO:0000313|Ensembl:ENSP00000430331};+++[H0YBN7_HUMAN|Unreviewed]SubName: Full=Squalene monooxygenase {ECO:0000313|Ensembl:ENSP00000429916}; Flags: Fragment;+++[Q5HYI4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686B0215 {ECO:0000313|EMBL:CAI46076.1};+++[Q9UNR6_HUMAN|Unreviewed]SubName: Full=Squalene epoxidase {ECO:0000313|EMBL:AAD10823.1}; EC=1.14.99.7 {ECO:0000313|EMBL:AAD10823.1}; SubName: Full=cDNA, FLJ93917, highly similar to Homo sapiens squalene epoxidase (SQLE), mRNA {ECO:0000313|EMBL:BAG36182.1};"]
[6726,"'SRP9'",1707,1703,2006,1805.33333333333,"03060///Protein export",{"$nulls":3},"GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0005785///signal recognition particle receptor complex+++GO:0005829///cytosol+++GO:0048500///signal recognition particle+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0005047///signal recognition particle binding+++GO:0008312///7S RNA binding","GO:0045900///negative regulation of translational elongation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation","signal recognition particle 9","[SRP09_HUMAN|Reviewed]RecName: Full=Signal recognition particle 9 kDa protein; Short=SRP9;+++[A0A024R3P3_HUMAN|Unreviewed]SubName: Full=Signal recognition particle 9kDa, isoform CRA_b {ECO:0000313|EMBL:EAW69752.1};+++[E9PE20_HUMAN|Unreviewed]SubName: Full=Signal recognition particle 9 kDa protein {ECO:0000313|Ensembl:ENSP00000355803};+++[Q6P2S0_HUMAN|Unreviewed]SubName: Full=SRP9 protein {ECO:0000313|EMBL:AAH64351.1};"]
[675,"'BRCA2'",9,10,9,9.33333333333333,"05224///Breast cancer+++03460///Fanconi anemia pathway+++05212///Pancreatic cancer+++03440///Homologous recombination+++05200///Pathways in cancer","H00031///Breast cancer+++H00238///Fanconi anemia+++H00027///Ovarian cancer+++H01554///Fallopian tube cancer+++H00019///Pancreatic cancer",null,null,"GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0030141///secretory granule+++GO:0005813///centrosome+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane+++GO:0000784///nuclear chromosome, telomeric region+++GO:0033593///BRCA2-MAGE-D1 complex+++GO:0000800///lateral element+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005856///cytoskeleton","GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding+++GO:0008022///protein C-terminus binding+++GO:0010485///H4 histone acetyltransferase activity+++GO:0004402///histone acetyltransferase activity+++GO:0002020///protease binding+++GO:0003677///DNA binding+++GO:0010484///H3 histone acetyltransferase activity","GO:0001833///inner cell mass cell proliferation+++GO:0010225///response to UV-C+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0007283///spermatogenesis+++GO:0043966///histone H3 acetylation+++GO:0007141///male meiosis I+++GO:0007569///cell aging+++GO:0001556///oocyte maturation+++GO:0043967///histone H4 acetylation+++GO:0043009///chordate embryonic development+++GO:0006302///double-strand break repair+++GO:0010332///response to gamma radiation+++GO:0006310///DNA recombination+++GO:0030097///hemopoiesis+++GO:1990426///mitotic recombination-dependent replication fork processing+++GO:0007420///brain development+++GO:0032465///regulation of cytokinesis+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0048478///replication fork protection+++GO:0070200///establishment of protein localization to telomere+++GO:0006289///nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010165///response to X-ray+++GO:0000724///double-strand break repair via homologous recombination+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0000281///mitotic cytokinesis+++GO:0006281///DNA repair+++GO:0008585///female gonad development+++GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0000722///telomere maintenance via recombination+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0051276///chromosome organization+++GO:0051298///centrosome duplication","BRCA2, DNA repair associated","[BRCA2_HUMAN|Reviewed]RecName: Full=Breast cancer type 2 susceptibility protein; AltName: Full=Fanconi anemia group D1 protein;+++[A0A068BC92_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83531.1}; Flags: Fragment;+++[A0A068BC94_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83536.1}; Flags: Fragment;+++[A0A068BCA8_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83561.1}; Flags: Fragment;+++[A0A068BCA9_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83566.1}; Flags: Fragment;+++[A0A068BCC2_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83586.1}; Flags: Fragment;+++[A0A068BDS2_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83533.1}; Flags: Fragment;+++[A0A068BDS6_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83538.1}; Flags: Fragment;+++[A0A068BDT0_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83543.1}; Flags: Fragment;+++[A0A068BDU2_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83563.1}; Flags: Fragment;+++[A0A068BDU4_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83568.1}; Flags: Fragment;+++[A0A068BDV3_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83583.1}; Flags: Fragment;+++[A0A068BEU0_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83532.1}; Flags: Fragment;+++[A0A068BEU4_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83537.1}; Flags: Fragment;+++[A0A068BEV8_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83562.1}; Flags: Fragment;+++[A0A068BEW3_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83567.1}; Flags: Fragment;+++[A0A068BEX2_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83587.1}; Flags: Fragment;+++[A0A068BFU2_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83530.1}; Flags: Fragment;+++[A0A068BFU7_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83535.1}; Flags: Fragment;+++[A0A068BFW6_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83560.1}; Flags: Fragment;+++[A0A068BFW8_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83565.1}; Flags: Fragment;+++[A0A068BFX3_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83570.1}; Flags: Fragment;+++[A0A068BFY4_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83585.1}; Flags: Fragment;+++[A0A068BI27_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83529.1}; Flags: Fragment;+++[A0A068BI30_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83534.1}; Flags: Fragment;+++[A0A068BI47_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83564.1}; Flags: Fragment;+++[A0A068BI50_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AIC83569.1}; Flags: Fragment;+++[A0A0A7E6R6_HUMAN|Unreviewed]SubName: Full=Truncated breast cancer type 2 susceptibility protein {ECO:0000313|EMBL:AIY60806.1}; Flags: Fragment;+++[A0A0F6RAD2_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50585.1}; Flags: Fragment;+++[A0A0F6RAD4_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50590.1}; Flags: Fragment;+++[A0A0F6RAD6_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50595.1}; Flags: Fragment;+++[A0A0F6RAU4_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50583.1}; Flags: Fragment;+++[A0A0F6RAU6_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50588.1}; Flags: Fragment;+++[A0A0F6RAU8_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50593.1}; Flags: Fragment;+++[A0A0F6TMQ3_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50584.1}; Flags: Fragment;+++[A0A0F6TMQ7_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50592.1}; Flags: Fragment;+++[A0A0F6TMZ6_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50586.1}; Flags: Fragment;+++[A0A0F6TMZ9_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50594.1}; Flags: Fragment;+++[A0A0F6TN25_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50587.1}; Flags: Fragment;+++[A0A0F6TN92_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50582.1}; Flags: Fragment;+++[A0A0F6TN97_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50591.1}; Flags: Fragment;+++[A0A0F6TNI0_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKE50589.1}; Flags: Fragment;+++[A0A0F7CSW3_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKG51649.1}; Flags: Fragment;+++[A0A0F7G9F8_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AKG51650.1}; Flags: Fragment;+++[A0A1S5WLI2_HUMAN|Unreviewed]SubName: Full=Truncated breast cancer 2 {ECO:0000313|EMBL:AQQ13115.1}; Flags: Fragment;+++[A0A248X3X9_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23221.1}; Flags: Fragment;+++[A0A248X3Y4_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23222.1}; Flags: Fragment;+++[A0A248X3Y7_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23225.1}; Flags: Fragment;+++[A0A248X3Y8_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23227.1}; Flags: Fragment;+++[A0A248X3Y9_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23228.1}; Flags: Fragment;+++[A0A248X3Z0_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23229.1}; Flags: Fragment;+++[A0A248X3Z1_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23230.1}; Flags: Fragment;+++[A0A248X3Z2_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23224.1}; Flags: Fragment;+++[A0A248X3Z3_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23226.1}; Flags: Fragment;+++[A0A248X3Z4_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23223.1}; Flags: Fragment;+++[A0A248X3Z5_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23231.1}; Flags: Fragment;+++[A0A248X3Z6_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:ASW23232.1}; Flags: Fragment;+++[A0A2S1WCJ3_HUMAN|Unreviewed]SubName: Full=BRCA2 {ECO:0000313|EMBL:AWJ64385.1}; Flags: Fragment;+++[A1YBP1_HUMAN|Unreviewed]SubName: Full=Breast and ovarian cancer susceptibility protein 2 truncated variant {ECO:0000313|EMBL:ABI74674.1};+++[H0YD86_HUMAN|Unreviewed]SubName: Full=Breast cancer type 2 susceptibility protein {ECO:0000313|Ensembl:ENSP00000433168}; Flags: Fragment;+++[H0YE37_HUMAN|Unreviewed]SubName: Full=Breast cancer type 2 susceptibility protein {ECO:0000313|Ensembl:ENSP00000434898}; Flags: Fragment;+++[K4JTS7_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88810.1}; Flags: Fragment;+++[K4JTT2_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88815.1}; Flags: Fragment;+++[K4JTT6_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88820.1}; Flags: Fragment;+++[K4JUC3_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88812.1}; Flags: Fragment;+++[K4JUC8_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88817.1}; Flags: Fragment;+++[K4JWF3_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88811.1}; Flags: Fragment;+++[K4JWF8_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88816.1}; Flags: Fragment;+++[K4JXT6_HUMAN|Unreviewed]SubName: Full=Breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88814.1}; Flags: Fragment;+++[K4JXU1_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88819.1}; Flags: Fragment;+++[K4K7V6_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88813.1}; Flags: Fragment;+++[K4K7W0_HUMAN|Unreviewed]SubName: Full=Truncated breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:AFU88818.1}; Flags: Fragment;+++[Q8IU64_HUMAN|Unreviewed]SubName: Full=Breast and ovarian cancer susceptibility protein {ECO:0000313|EMBL:AAN61409.1}; SubName: Full=Breast cancer susceptibility protein BRCA2 {ECO:0000313|EMBL:AAN28944.1}; Flags: Fragment;+++[Q8IU77_HUMAN|Unreviewed]SubName: Full=Breast and ovarian cancer susceptibility protein {ECO:0000313|EMBL:AAN61426.1}; Flags: Fragment;+++[Q8IU82_HUMAN|Unreviewed]SubName: Full=Breast and ovarian cancer susceptibility protein {ECO:0000313|EMBL:AAN61434.1}; Flags: Fragment;+++[Q9BX99_HUMAN|Unreviewed]SubName: Full=Mutant early onset breast cancer susceptibility protein 2 {ECO:0000313|EMBL:AAK29432.1}; Flags: Fragment;+++[Q9H265_HUMAN|Unreviewed]SubName: Full=BRCA2 protein {ECO:0000313|EMBL:AAG46030.1}; Flags: Fragment;+++[Q9H4L2_HUMAN|Unreviewed]SubName: Full=Breast cancer 2 tumor suppressor {ECO:0000313|EMBL:AAG32682.1}; Flags: Fragment;+++[Q9H4L3_HUMAN|Unreviewed]SubName: Full=Breast and ovarian cancer susceptibility protein 2 {ECO:0000313|EMBL:ABJ90481.1}; SubName: Full=Breast cancer 2 tumor suppressor {ECO:0000313|EMBL:AAG32681.1}; Flags: Fragment;"]
[6769,"'STAC'",281,258,230,256.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0042383///sarcolemma+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0030315///T-tubule+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0046872///metal ion binding","GO:1901385///regulation of voltage-gated calcium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:2001259///positive regulation of cation channel activity+++GO:0034605///cellular response to heat+++GO:0006936///muscle contraction+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007165///signal transduction+++GO:0035556///intracellular signal transduction","SH3 and cysteine rich domain","[STAC_HUMAN|Reviewed]RecName: Full=SH3 and cysteine-rich domain-containing protein; AltName: Full=Src homology 3 and cysteine-rich domain-containing protein;+++[B4DR96_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60332, moderately similar to SH3 and cysteine-rich domain-containing protein {ECO:0000313|EMBL:BAG61208.1};+++[B4DZ13_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54661, highly similar to SH3 and cysteine-rich domain-containing protein {ECO:0000313|EMBL:BAG63925.1};+++[C9J3Z9_HUMAN|Unreviewed]SubName: Full=SH3 and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000398403}; Flags: Fragment;+++[E9PEA7_HUMAN|Unreviewed]SubName: Full=SH3 and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000393713};+++[F8WB25_HUMAN|Unreviewed]SubName: Full=SH3 and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000397521};+++[Q8WUK8_HUMAN|Unreviewed]SubName: Full=SH3 and cysteine rich domain {ECO:0000313|EMBL:AAH20221.1};"]
[6794,"'STK11'",984,1181,1267,1144,"04530///Tight junction+++04068///FoxO signaling pathway+++04140///Autophagy - animal+++04150///mTOR signaling pathway+++04152///AMPK signaling pathway+++04920///Adipocytokine signaling pathway+++04151///PI3K-Akt signaling pathway+++04211///Longevity regulating pathway","H00666///Peutz-Jeghers syndrome+++H00019///Pancreatic cancer",null,null,"GO:0005739///mitochondrion+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0000166///nucleotide binding+++GO:0030295///protein kinase activator activity+++GO:0030275///LRR domain binding+++GO:0005515///protein binding+++GO:0002039///p53 binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0016310///phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0071493///cellular response to UV-B+++GO:0001944///vasculature development+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0032147///activation of protein kinase activity+++GO:0001558///regulation of cell growth+++GO:0042593///glucose homeostasis+++GO:0007049///cell cycle+++GO:0045059///positive thymic T cell selection+++GO:0001894///tissue homeostasis+++GO:0030308///negative regulation of cell growth+++GO:0046777///protein autophosphorylation+++GO:0007050///cell cycle arrest+++GO:0043276///anoikis+++GO:0051645///Golgi localization+++GO:0010212///response to ionizing radiation+++GO:0060070///canonical Wnt signaling pathway+++GO:0006470///protein dephosphorylation+++GO:0006914///autophagy+++GO:0006974///cellular response to DNA damage stimulus+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0007409///axonogenesis+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0030111///regulation of Wnt signaling pathway+++GO:0007283///spermatogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0097484///dendrite extension+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0050772///positive regulation of axonogenesis+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0006915///apoptotic process+++GO:0051896///regulation of protein kinase B signaling+++GO:0050852///T cell receptor signaling pathway+++GO:1904262///negative regulation of TORC1 signaling+++GO:0048814///regulation of dendrite morphogenesis+++GO:0030154///cell differentiation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0010508///positive regulation of autophagy","serine/threonine kinase 11","[STK11_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase STK11; EC=2.7.11.1; AltName: Full=Liver kinase B1; Short=LKB1; Short=hLKB1; AltName: Full=Renal carcinoma antigen NY-REN-19; Flags: Precursor;+++[A0A087WT72_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase STK11 {ECO:0000313|Ensembl:ENSP00000477641}; Flags: Fragment;+++[A0A0S2Z4C7_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 11 isoform 3 {ECO:0000313|EMBL:ALQ33798.1}; Flags: Fragment;+++[A0A0S2Z4D1_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 11 isoform 1 {ECO:0000313|EMBL:ALQ33797.1}; Flags: Fragment;+++[A0A1B0GUW2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase STK11 {ECO:0000313|Ensembl:ENSP00000490268}; Flags: Fragment;+++[D4P556_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 11 {ECO:0000313|EMBL:ADD71158.1}; Flags: Fragment;+++[K7EMR0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase STK11 {ECO:0000313|Ensembl:ENSP00000466610};+++[K7EP59_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase STK11 {ECO:0000313|Ensembl:ENSP00000467240};+++[K7EQN8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase STK11 {ECO:0000313|Ensembl:ENSP00000467912}; Flags: Fragment;+++[Q5ZEZ1_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 11 {ECO:0000313|EMBL:CAH59749.2}; Flags: Fragment;+++[Q9NS52_HUMAN|Unreviewed]SubName: Full=STK11 [amino acids 371-433] {ECO:0000313|EMBL:AAF97257.1}; Flags: Fragment;"]
[6814,"'STXBP3'",198,231,202,210.333333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0098793///presynapse+++GO:0045335///phagocytic vesicle+++GO:0016020///membrane+++GO:0031091///platelet alpha granule+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0070062///extracellular exosome+++GO:0016323///basolateral plasma membrane+++GO:0070820///tertiary granule+++GO:0042581///specific granule+++GO:0005829///cytosol","GO:0017075///syntaxin-1 binding+++GO:0005515///protein binding+++GO:0019905///syntaxin binding","GO:0006887///exocytosis+++GO:0007420///brain development+++GO:0001678///cellular glucose homeostasis+++GO:0051291///protein heterooligomerization+++GO:0015031///protein transport+++GO:0022615///protein to membrane docking+++GO:0043312///neutrophil degranulation+++GO:0006904///vesicle docking involved in exocytosis+++GO:0016192///vesicle-mediated transport+++GO:0071346///cellular response to interferon-gamma+++GO:0032868///response to insulin+++GO:0070527///platelet aggregation+++GO:0046325///negative regulation of glucose import+++GO:0045955///negative regulation of calcium ion-dependent exocytosis+++GO:0030073///insulin secretion","syntaxin binding protein 3","[STXB3_HUMAN|Reviewed]RecName: Full=Syntaxin-binding protein 3; AltName: Full=Platelet Sec1 protein; Short=PSP; AltName: Full=Protein unc-18 homolog 3; Short=Unc18-3; AltName: Full=Protein unc-18 homolog C; Short=Unc-18C;"]
[6844,"'VAMP2'",1655,1503,1700,1619.33333333333,"04911///Insulin secretion+++04130///SNARE interactions in vesicular transport+++04721///Synaptic vesicle cycle+++04970///Salivary secretion+++04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0008021///synaptic vesicle+++GO:0030136///clathrin-coated vesicle+++GO:0031982///vesicle+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0070032///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0070044///synaptobrevin 2-SNAP-25-syntaxin-1a complex+++GO:0005886///plasma membrane+++GO:0030672///synaptic vesicle membrane+++GO:0031201///SNARE complex+++GO:0044306///neuron projection terminus+++GO:0070033///synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex+++GO:0008076///voltage-gated potassium channel complex+++GO:0042589///zymogen granule membrane+++GO:0043005///neuron projection+++GO:0060203///clathrin-sculpted glutamate transport vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0061202///clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0070083///clathrin-sculpted monoamine transport vesicle membrane+++GO:0030667///secretory granule membrane","GO:0048306///calcium-dependent protein binding+++GO:0000149///SNARE binding+++GO:0017075///syntaxin-1 binding+++GO:0019905///syntaxin binding+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0043621///protein self-association+++GO:0005543///phospholipid binding","GO:0061025///membrane fusion+++GO:0043312///neutrophil degranulation+++GO:0014047///glutamate secretion+++GO:0032869///cellular response to insulin stimulus+++GO:0006887///exocytosis+++GO:0043308///eosinophil degranulation+++GO:0016079///synaptic vesicle exocytosis+++GO:0060291///long-term synaptic potentiation+++GO:0061024///membrane organization+++GO:0070254///mucus secretion+++GO:0017157///regulation of exocytosis+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:0009749///response to glucose+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0017156///calcium ion regulated exocytosis+++GO:0090316///positive regulation of intracellular protein transport+++GO:0015031///protein transport+++GO:0060627///regulation of vesicle-mediated transport+++GO:0043320///natural killer cell degranulation+++GO:0016192///vesicle-mediated transport+++GO:0065003///protein-containing complex assembly+++GO:1903593///regulation of histamine secretion by mast cell","vesicle associated membrane protein 2","[VAMP2_HUMAN|Reviewed]RecName: Full=Vesicle-associated membrane protein 2; Short=VAMP-2; AltName: Full=Synaptobrevin-2;+++[F8WCA0_HUMAN|Unreviewed]SubName: Full=Vesicle-associated membrane protein 2 {ECO:0000313|Ensembl:ENSP00000418572};+++[J3QRU4_HUMAN|Unreviewed]SubName: Full=Vesicle-associated membrane protein 2 {ECO:0000313|Ensembl:ENSP00000467399};+++[K7ENK9_HUMAN|Unreviewed]SubName: Full=Vesicle-associated membrane protein 2 {ECO:0000313|Ensembl:ENSP00000466995};"]
[6856,"'SYPL1'",278,285,290,284.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0008021///synaptic vesicle+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0030141///secretory granule+++GO:0016020///membrane+++GO:0042470///melanosome",null,"GO:0007268///chemical synaptic transmission","synaptophysin like 1","[SYPL1_HUMAN|Reviewed]RecName: Full=Synaptophysin-like protein 1; AltName: Full=Pantophysin;+++[A0A0U1RQT9_HUMAN|Unreviewed]SubName: Full=Synaptophysin-like protein 1 {ECO:0000313|Ensembl:ENSP00000489167}; Flags: Fragment;+++[A4D0R1_HUMAN|Unreviewed]SubName: Full=Synaptophysin-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW83379.1}; SubName: Full=Synaptophysin-like protein {ECO:0000313|EMBL:EAL24401.1};+++[C9JYN0_HUMAN|Unreviewed]SubName: Full=Synaptophysin-like protein 1 {ECO:0000313|Ensembl:ENSP00000419070};+++[H7C4J8_HUMAN|Unreviewed]SubName: Full=Synaptophysin-like protein 1 {ECO:0000313|Ensembl:ENSP00000417473}; Flags: Fragment;"]
[6884,"'TAF13'",53,75,79,69,"05168///Herpes simplex infection+++03022///Basal transcription factors","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005669///transcription factor TFIID complex+++GO:0005654///nucleoplasm","GO:0008022///protein C-terminus binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003712///transcription coregulator activity+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0006352///DNA-templated transcription, initiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II","TATA-box binding protein associated factor 13","[TAF13_HUMAN|Reviewed]RecName: Full=Transcription initiation factor TFIID subunit 13 {ECO:0000305}; AltName: Full=Transcription initiation factor TFIID 18 kDa subunit {ECO:0000303|PubMed:7729427}; Short=TAF(II)18 {ECO:0000303|PubMed:9695952}; Short=TAFII-18 {ECO:0000305}; Short=TAFII18 {ECO:0000303|PubMed:7729427};+++[A0A024R089_HUMAN|Unreviewed]SubName: Full=TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa, isoform CRA_a {ECO:0000313|EMBL:EAW56355.1};+++[Q0VA92_HUMAN|Unreviewed]SubName: Full=TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa {ECO:0000313|EMBL:AAI21182.1};"]
[6894,"'TARBP1'",220.01,204,173.84,199.283333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0003723///RNA binding+++GO:0008168///methyltransferase activity+++GO:0008173///RNA methyltransferase activity+++GO:0016423///tRNA (guanine) methyltransferase activity","GO:0032259///methylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006396///RNA processing+++GO:0030488///tRNA methylation","TAR (HIV-1) RNA binding protein 1","[TARB1_HUMAN|Reviewed]RecName: Full=Probable methyltransferase TARBP1; EC=2.1.1.-; AltName: Full=TAR RNA-binding protein 1; AltName: Full=TAR RNA-binding protein of 185 kDa; Short=TRP-185;"]
[6905,"'TBCE'",279,258,305,280.666666666667,null,"H00622///Hypoparathyroidism-retardation-dysmorphism syndrome+++H00619///Kenny-Caffey syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005840///ribosome+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0051087///chaperone binding+++GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0007052///mitotic spindle organization+++GO:0006457///protein folding+++GO:0008299///isoprenoid biosynthetic process+++GO:0000226///microtubule cytoskeleton organization+++GO:0007023///post-chaperonin tubulin folding pathway","tubulin folding cofactor E","[TBCE_HUMAN|Reviewed]RecName: Full=Tubulin-specific chaperone E; AltName: Full=Tubulin-folding cofactor E;+++[A0A2R8Y3S1_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000493539}; Flags: Fragment;+++[A0A2R8Y4E7_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000493737}; Flags: Fragment;+++[A0A2R8Y4N4_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494196};+++[A0A2R8Y4P2_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494208};+++[A0A2R8Y4V6_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494102};+++[A0A2R8Y551_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494203}; Flags: Fragment;+++[A0A2R8Y597_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494291};+++[A0A2R8Y5H6_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494541};+++[A0A2R8Y5Q8_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000494646};+++[A0A2R8Y6G3_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495295}; Flags: Fragment;+++[A0A2R8Y6L2_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495319}; Flags: Fragment;+++[A0A2R8Y6Q1_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495693}; SubName: Full=Tubulin-specific chaperone e, isoform CRA_b {ECO:0000313|EMBL:EAW70022.1};+++[A0A2R8Y720_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495738}; Flags: Fragment;+++[A0A2R8Y784_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495916};+++[A0A2R8Y787_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495928};+++[A0A2R8Y7E7_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495953};+++[A0A2R8Y7H8_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496033}; Flags: Fragment;+++[A0A2R8Y7P7_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496173};+++[A0A2R8Y809_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496380};+++[A0A2R8Y897_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496612}; Flags: Fragment;+++[A0A2R8YE82_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495370};+++[A0A2R8YER9_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495831};+++[A0A2R8YF12_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496048}; Flags: Fragment;+++[A0A2R8YFG9_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495125}; Flags: Fragment;+++[A0A2R8YFL4_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495225}; Flags: Fragment;+++[A0A2R8YFM3_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000495257};+++[A0A2R8YH53_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496495};+++[A0A2R8YHI9_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000496773};+++[A0A2U3TZJ6_HUMAN|Unreviewed]SubName: Full=Tubulin-specific chaperone E {ECO:0000313|Ensembl:ENSP00000355560}; SubName: Full=Tubulin-specific chaperone e, isoform CRA_c {ECO:0000313|EMBL:EAW70023.1};"]
[6926,"'TBX3'",37,49,43,43,"04550///Signaling pathways regulating pluripotency of stem cells","H00637///Ulnar-mammary syndrome",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0035136///forelimb morphogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0060923///cardiac muscle cell fate commitment+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0055007///cardiac muscle cell differentiation+++GO:0060931///sinoatrial node cell development+++GO:0008595///anterior/posterior axis specification, embryo+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0030540///female genitalia development+++GO:0035050///embryonic heart tube development+++GO:0032275///luteinizing hormone secretion+++GO:0007569///cell aging+++GO:0060412///ventricular septum morphogenesis+++GO:0042733///embryonic digit morphogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035108///limb morphogenesis+++GO:0001501///skeletal system development+++GO:0035115///embryonic forelimb morphogenesis+++GO:0001947///heart looping+++GO:0030539///male genitalia development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042127///regulation of cell proliferation+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0003167///atrioventricular bundle cell differentiation+++GO:0003007///heart morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0001701///in utero embryonic development+++GO:0030879///mammary gland development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0046884///follicle-stimulating hormone secretion+++GO:0009887///animal organ morphogenesis+++GO:2000648///positive regulation of stem cell proliferation+++GO:0090398///cellular senescence+++GO:0006355///regulation of transcription, DNA-templated+++GO:0019827///stem cell population maintenance+++GO:0045787///positive regulation of cell cycle+++GO:0060596///mammary placode formation+++GO:0003151///outflow tract morphogenesis+++GO:0060021///roof of mouth development+++GO:0048332///mesoderm morphogenesis+++GO:0045662///negative regulation of myoblast differentiation+++GO:0010159///specification of animal organ position+++GO:0001568///blood vessel development+++GO:0007275///multicellular organism development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021761///limbic system development","T-box 3","[TBX3_HUMAN|Reviewed]RecName: Full=T-box transcription factor TBX3; Short=T-box protein 3;+++[A0A024RBL6_HUMAN|Unreviewed]SubName: Full=T-box 3 (Ulnar mammary syndrome), isoform CRA_c {ECO:0000313|EMBL:EAW98073.1};+++[A0A024RBQ4_HUMAN|Unreviewed]SubName: Full=T-box 3 (Ulnar mammary syndrome), isoform CRA_a {ECO:0000313|EMBL:EAW98074.1};"]
[6954,"'TCP11'",0,1,3,1.33333333333333,{"$nulls":4},"GO:0001669///acrosomal vesicle+++GO:0097225///sperm midpiece+++GO:0016021///integral component of membrane+++GO:0036126///sperm flagellum+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0031514///motile cilium+++GO:0016020///membrane+++GO:0005929///cilium","GO:0005515///protein binding","GO:0010737///protein kinase A signaling+++GO:0007283///spermatogenesis+++GO:1902490///regulation of sperm capacitation+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation","t-complex 11","[TCP11_HUMAN|Reviewed]RecName: Full=T-complex protein 11 homolog;+++[A0A140VK95_HUMAN|Unreviewed]SubName: Full=Testis secretory sperm-binding protein Li 222n {ECO:0000313|EMBL:AEE61232.1};+++[B7ZAT8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79302, highly similar to Homo sapiens t-complex 11(TCP11), mRNA {ECO:0000313|EMBL:BAH14774.1};+++[D6R8Y5_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000422259};+++[D6R989_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000423293};+++[D6R9D8_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000422940};+++[D6R9R9_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000423183}; Flags: Fragment;+++[D6RAC0_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000422774}; Flags: Fragment;+++[D6RBE4_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000424209};+++[D6RFY8_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000421386};+++[D6RG02_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000421349};+++[D6RGC0_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000421333}; Flags: Fragment;+++[D6RGY5_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000421103}; Flags: Fragment;+++[D6RIW4_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000425849};+++[H0Y8T8_HUMAN|Unreviewed]SubName: Full=T-complex protein 11 homolog {ECO:0000313|Ensembl:ENSP00000422105}; Flags: Fragment;"]
[7004,"'TEAD4'",231,241,224,232,"04392///Hippo signaling pathway - multiple species+++04391///Hippo signaling pathway - fly+++04011///MAPK signaling pathway - yeast+++04390///Hippo signaling pathway","H01180///Sveinsson chorioretinal atrophy (SCRA)","M00683///Hippo signaling",null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex","GO:0044212///transcription regulatory region DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0007517///muscle organ development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0001501///skeletal system development+++GO:0006351///transcription, DNA-templated+++GO:0035329///hippo signaling+++GO:0006355///regulation of transcription, DNA-templated","TEA domain transcription factor 4","[TEAD4_HUMAN|Reviewed]RecName: Full=Transcriptional enhancer factor TEF-3; AltName: Full=TEA domain family member 4; Short=TEAD-4; AltName: Full=Transcription factor 13-like 1; AltName: Full=Transcription factor RTEF-1;+++[A0A0A0MRF3_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSP00000351184};+++[A0A0S2Z4E5_HUMAN|Unreviewed]SubName: Full=TEA domain family member 4 isoform 3 {ECO:0000313|EMBL:ALQ33814.1}; Flags: Fragment;+++[A0A0S2Z4F2_HUMAN|Unreviewed]SubName: Full=TEA domain family member 4 isoform 2 {ECO:0000313|EMBL:ALQ33813.1};+++[D3DUQ6_HUMAN|Unreviewed]SubName: Full=TEA domain family member 4 isoform 1 {ECO:0000313|EMBL:ALQ33812.1}; SubName: Full=TEA domain family member 4, isoform CRA_b {ECO:0000313|EMBL:EAW88875.1};+++[H0Y7B0_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSP00000411475};+++[H0YFF9_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSP00000438453}; Flags: Fragment;+++[H0YFK0_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSP00000438960}; Flags: Fragment;+++[H0YG62_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSP00000441959}; Flags: Fragment;+++[H0YGS2_HUMAN|Unreviewed]SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSP00000444528}; Flags: Fragment;+++[Q53GI4_HUMAN|Unreviewed]SubName: Full=TEA domain family member 4 isoform 1 variant {ECO:0000313|EMBL:BAD96667.1}; SubName: Full=Transcriptional enhancer factor TEF-3 {ECO:0000313|Ensembl:ENSP00000352926}; Flags: Fragment;"]
[7026,"'NR2F2'",1892,2254,2010,2052,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0001972///retinoic acid binding+++GO:0003714///transcription corepressor activity+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003707///steroid hormone receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0004879///nuclear receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009956///radial pattern formation+++GO:0060849///regulation of transcription involved in lymphatic endothelial cell fate commitment+++GO:0030522///intracellular receptor signaling pathway+++GO:0060674///placenta blood vessel development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007165///signal transduction+++GO:0001945///lymph vessel development+++GO:0006629///lipid metabolic process+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0001764///neuron migration+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0060173///limb development+++GO:0009952///anterior/posterior pattern specification+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0060707///trophoblast giant cell differentiation+++GO:0007519///skeletal muscle tissue development+++GO:0003084///positive regulation of systemic arterial blood pressure+++GO:0010596///negative regulation of endothelial cell migration+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001893///maternal placenta development+++GO:0048514///blood vessel morphogenesis+++GO:0032355///response to estradiol+++GO:0001701///in utero embryonic development+++GO:0030900///forebrain development+++GO:0009566///fertilization","nuclear receptor subfamily 2 group F member 2","[COT2_HUMAN|Reviewed]RecName: Full=COUP transcription factor 2; Short=COUP-TF2; AltName: Full=Apolipoprotein A-I regulatory protein 1; Short=ARP-1; AltName: Full=COUP transcription factor II; Short=COUP-TF II; AltName: Full=Nuclear receptor subfamily 2 group F member 2;+++[F1D8R0_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2, group F, member 2, isoform CRA_a {ECO:0000313|EMBL:EAX02198.1}; SubName: Full=Ovalbumin upstream promoter-transcription factor II variant 1 {ECO:0000313|EMBL:ADZ17359.1};+++[H3BTC2_HUMAN|Unreviewed]SubName: Full=COUP transcription factor 2 {ECO:0000313|Ensembl:ENSP00000457112}; Flags: Fragment;"]
[7044,"'LEFTY2'",307,252,355,304.666666666667,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0031093///platelet alpha granule lumen+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix","GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0005160///transforming growth factor beta receptor binding","GO:0048468///cell development+++GO:0007275///multicellular organism development+++GO:0010469///regulation of signaling receptor activity+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0002576///platelet degranulation+++GO:0060395///SMAD protein signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0042981///regulation of apoptotic process+++GO:0007179///transforming growth factor beta receptor signaling pathway","left-right determination factor 2","[LFTY2_HUMAN|Reviewed]RecName: Full=Left-right determination factor 2; AltName: Full=Endometrial bleeding-associated factor; AltName: Full=Left-right determination factor A; AltName: Full=Protein lefty-2; AltName: Full=Protein lefty-A; AltName: Full=Transforming growth factor beta-4; Short=TGF-beta-4; Flags: Precursor;+++[A0A024R3P5_HUMAN|Unreviewed]RecName: Full=Left-right determination factor {ECO:0000256|PIRNR:PIRNR037402};"]
[7066,"'THPO'",2,3,4,3,"04060///Cytokine-cytokine receptor interaction+++04630///Jak-STAT signaling pathway+++04640///Hematopoietic cell lineage",{"$nulls":3},"GO:0009986///cell surface+++GO:0005576///extracellular region+++GO:0005887///integral component of plasma membrane+++GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0005179///hormone activity+++GO:0005125///cytokine activity+++GO:0004447///iodide peroxidase activity+++GO:0005509///calcium ion binding+++GO:0016491///oxidoreductase activity+++GO:0008083///growth factor activity+++GO:0005102///signaling receptor binding+++GO:0004601///peroxidase activity+++GO:0020037///heme binding","GO:0045654///positive regulation of megakaryocyte differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010469///regulation of signaling receptor activity+++GO:0042446///hormone biosynthetic process+++GO:0006979///response to oxidative stress+++GO:1902035///positive regulation of hematopoietic stem cell proliferation+++GO:0098869///cellular oxidant detoxification+++GO:0008283///cell proliferation+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0042744///hydrogen peroxide catabolic process+++GO:0006590///thyroid hormone generation+++GO:0030099///myeloid cell differentiation+++GO:0035162///embryonic hemopoiesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0007275///multicellular organism development+++GO:0055114///oxidation-reduction process","thrombopoietin","[TPO_HUMAN|Reviewed]RecName: Full=Thrombopoietin; AltName: Full=C-mpl ligand; Short=ML; AltName: Full=Megakaryocyte colony-stimulating factor; AltName: Full=Megakaryocyte growth and development factor; Short=MGDF; AltName: Full=Myeloproliferative leukemia virus oncogene ligand; Flags: Precursor;+++[A0A2R8Y734_HUMAN|Unreviewed]SubName: Full=Thrombopoietin {ECO:0000313|Ensembl:ENSP00000495689}; Flags: Fragment;+++[F8W6L1_HUMAN|Unreviewed]SubName: Full=Thrombopoietin {ECO:0000313|Ensembl:ENSP00000411704};+++[Q5FBX4_HUMAN|Unreviewed]SubName: Full=Thrombopoietin nirs variant 3 {ECO:0000313|EMBL:BAD89423.1};+++[Q5FBX6_HUMAN|Unreviewed]SubName: Full=Thrombopoietin nirs variant 2 {ECO:0000313|EMBL:BAD89421.1};+++[Q5FBX8_HUMAN|Unreviewed]SubName: Full=Thrombopoietin nirs variant 1 {ECO:0000313|EMBL:BAD89419.1};"]
[708,"'C1QBP'",943,843,862,882.666666666667,"05168///Herpes simplex infection","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005730///nucleolus+++GO:0005759///mitochondrial matrix+++GO:0009986///cell surface+++GO:0098982///GABA-ergic synapse+++GO:0005737///cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0005615///extracellular space+++GO:0048786///presynaptic active zone+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0098793///presynapse+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0005080///protein kinase C binding+++GO:0005540///hyaluronic acid binding+++GO:0097177///mitochondrial ribosome binding+++GO:0008134///transcription factor binding+++GO:0001849///complement component C1q binding+++GO:0003729///mRNA binding+++GO:0008494///translation activator activity+++GO:0031690///adrenergic receptor binding+++GO:0030984///kininogen binding+++GO:0003714///transcription corepressor activity+++GO:0005515///protein binding","GO:2000510///positive regulation of dendritic cell chemotaxis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042254///ribosome biogenesis+++GO:0042256///mature ribosome assembly+++GO:0006915///apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0039534///negative regulation of MDA-5 signaling pathway+++GO:0090023///positive regulation of neutrophil chemotaxis+++GO:0006955///immune response+++GO:0043065///positive regulation of apoptotic process+++GO:0016032///viral process+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0045087///innate immune response+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0070131///positive regulation of mitochondrial translation+++GO:0007597///blood coagulation, intrinsic pathway+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0050687///negative regulation of defense response to virus+++GO:0006958///complement activation, classical pathway+++GO:1901165///positive regulation of trophoblast cell migration+++GO:0002250///adaptive immune response+++GO:0030449///regulation of complement activation+++GO:0048025///negative regulation of mRNA splicing, via spliceosome+++GO:0002376///immune system process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032689///negative regulation of interferon-gamma production","complement C1q binding protein","[C1QBP_HUMAN|Reviewed]RecName: Full=Complement component 1 Q subcomponent-binding protein, mitochondrial; AltName: Full=ASF/SF2-associated protein p32; AltName: Full=Glycoprotein gC1qBP; Short=C1qBP; AltName: Full=Hyaluronan-binding protein 1; AltName: Full=Mitochondrial matrix protein p32; AltName: Full=gC1q-R protein; AltName: Full=p33; Short=SF2AP32 {ECO:0000303|PubMed:18191643}; Flags: Precursor;+++[A0A0G2JLC0_HUMAN|Unreviewed]SubName: Full=Complement component 1 Q subcomponent-binding protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000458624}; Flags: Fragment;+++[I3L3B0_HUMAN|Unreviewed]SubName: Full=Complement component 1 Q subcomponent-binding protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000460308}; SubName: Full=Complement component 1, q subcomponent binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW90335.1};+++[I3L3Q7_HUMAN|Unreviewed]SubName: Full=Complement component 1 Q subcomponent-binding protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000460638}; Flags: Fragment;"]
[7099,"'TLR4'",44,21,19,28,"05321///Inflammatory bowel disease (IBD)+++05205///Proteoglycans in cancer+++05145///Toxoplasmosis+++04621///NOD-like receptor signaling pathway+++05164///Influenza A+++05132///Salmonella infection+++04217///Necroptosis+++05142///Chagas disease (American trypanosomiasis)+++04620///Toll-like receptor signaling pathway+++05162///Measles+++04151///PI3K-Akt signaling pathway+++04066///HIF-1 signaling pathway+++05152///Tuberculosis+++05146///Amoebiasis+++04145///Phagosome+++05134///Legionellosis+++05130///Pathogenic Escherichia coli infection+++04064///NF-kappa B signaling pathway+++05323///Rheumatoid arthritis+++05144///Malaria+++05161///Hepatitis B+++05133///Pertussis+++05140///Leishmaniasis","H00821///Age-related macular degeneration","M00686///Toll-like receptor signaling",null,"GO:0005622///intracellular+++GO:0005887///integral component of plasma membrane+++GO:0031226///intrinsic component of plasma membrane+++GO:0010008///endosome membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0046696///lipopolysaccharide receptor complex+++GO:0009897///external side of plasma membrane+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0043235///receptor complex+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0001530///lipopolysaccharide binding+++GO:0046982///protein heterodimerization activity+++GO:0001875///lipopolysaccharide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0042802///identical protein binding+++GO:0038023///signaling receptor activity","GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:0006954///inflammatory response+++GO:0070430///positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0030890///positive regulation of B cell proliferation+++GO:0032496///response to lipopolysaccharide+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0046330///positive regulation of JNK cascade+++GO:1904646///cellular response to amyloid-beta+++GO:0032729///positive regulation of interferon-gamma production+++GO:0032733///positive regulation of interleukin-10 production+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0032757///positive regulation of interleukin-8 production+++GO:0071223///cellular response to lipoteichoic acid+++GO:0002537///nitric oxide production involved in inflammatory response+++GO:0032609///interferon-gamma production+++GO:0032497///detection of lipopolysaccharide+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0002756///MyD88-independent toll-like receptor signaling pathway+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0032728///positive regulation of interferon-beta production+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0006955///immune response+++GO:0070266///necroptotic process+++GO:0050702///interleukin-1 beta secretion+++GO:0002730///regulation of dendritic cell cytokine production+++GO:0031663///lipopolysaccharide-mediated signaling pathway+++GO:0045359///positive regulation of interferon-beta biosynthetic process+++GO:0032707///negative regulation of interleukin-23 production+++GO:0032727///positive regulation of interferon-alpha production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0045416///positive regulation of interleukin-8 biosynthetic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007252///I-kappaB phosphorylation+++GO:0042535///positive regulation of tumor necrosis factor biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0032732///positive regulation of interleukin-1 production+++GO:0050727///regulation of inflammatory response+++GO:0016046///detection of fungus+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:0034128///negative regulation of MyD88-independent toll-like receptor signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0042742///defense response to bacterium+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0070434///positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway+++GO:0032735///positive regulation of interleukin-12 production+++GO:0050829///defense response to Gram-negative bacterium+++GO:0010628///positive regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032689///negative regulation of interferon-gamma production+++GO:0045087///innate immune response+++GO:0010572///positive regulation of platelet activation+++GO:0043032///positive regulation of macrophage activation+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0007165///signal transduction+++GO:0097190///apoptotic signaling pathway+++GO:1903974///positive regulation of cellular response to macrophage colony-stimulating factor stimulus+++GO:0000187///activation of MAPK activity+++GO:0042088///T-helper 1 type immune response+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:0050707///regulation of cytokine secretion+++GO:0045084///positive regulation of interleukin-12 biosynthetic process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0032722///positive regulation of chemokine production+++GO:0071346///cellular response to interferon-gamma+++GO:0002218///activation of innate immune response+++GO:0032700///negative regulation of interleukin-17 production+++GO:0014002///astrocyte development+++GO:0002376///immune system process+++GO:0009617///response to bacterium+++GO:0002224///toll-like receptor signaling pathway+++GO:0042116///macrophage activation+++GO:0032715///negative regulation of interleukin-6 production+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0045348///positive regulation of MHC class II biosynthetic process+++GO:0050729///positive regulation of inflammatory response+++GO:0002322///B cell proliferation involved in immune response+++GO:0071260///cellular response to mechanical stimulus+++GO:0060729///intestinal epithelial structure maintenance","toll like receptor 4","[TLR4_HUMAN|Reviewed]RecName: Full=Toll-like receptor 4; AltName: Full=hToll; AltName: CD_antigen=CD284; Flags: Precursor;+++[A0A2R8Y7P4_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|Ensembl:ENSP00000496429};+++[D0EWT7_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACX46980.1}; Flags: Fragment;+++[D0EWT8_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACX46981.1}; Flags: Fragment;+++[D0EWT9_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACX46982.1}; Flags: Fragment;+++[D1CS55_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:AAY82270.1};+++[D2JYI2_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69536.1}; Flags: Fragment;+++[D2JYI3_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69537.1}; Flags: Fragment;+++[D2JYI4_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69538.1}; Flags: Fragment;+++[D2JYI5_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69539.1}; Flags: Fragment;+++[D2JYI6_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69540.1}; Flags: Fragment;+++[D2JYI7_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69541.1}; Flags: Fragment;+++[D2JYI8_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69542.1}; Flags: Fragment;+++[D2JYI9_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:ACZ69543.1}; Flags: Fragment;"]
[7113,"'TMPRSS2'",10,10,7,9,"05215///Prostate cancer+++05202///Transcriptional misregulation in cancer+++05164///Influenza A",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0005044///scavenger receptor activity","GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis+++GO:0046598///positive regulation of viral entry into host cell+++GO:0016540///protein autoprocessing","transmembrane serine protease 2","[TMPS2_HUMAN|Reviewed]RecName: Full=Transmembrane protease serine 2; EC=3.4.21.-; AltName: Full=Serine protease 10; Contains: RecName: Full=Transmembrane protease serine 2 non-catalytic chain; Contains: RecName: Full=Transmembrane protease serine 2 catalytic chain; Flags: Precursor;+++[C9J5Y1_HUMAN|Unreviewed]SubName: Full=Transmembrane protease serine 2 {ECO:0000313|Ensembl:ENSP00000397846}; Flags: Fragment;+++[C9JB05_HUMAN|Unreviewed]SubName: Full=Transmembrane protease serine 2 {ECO:0000313|Ensembl:ENSP00000391784}; Flags: Fragment;+++[C9JKZ3_HUMAN|Unreviewed]SubName: Full=Transmembrane protease serine 2 {ECO:0000313|Ensembl:ENSP00000389006}; Flags: Fragment;+++[Q96T73_HUMAN|Unreviewed]SubName: Full=Epitheliasin {ECO:0000313|EMBL:AAK53559.1};"]
[7139,"'TNNT2'",110,92,157,119.666666666667,"04261///Adrenergic signaling in cardiomyocytes+++05414///Dilated cardiomyopathy (DCM)+++05410///Hypertrophic cardiomyopathy (HCM)+++04260///Cardiac muscle contraction","H00294///Dilated cardiomyopathy (DCM)+++H01216///Left ventricular noncompaction (LVNC)+++H01219///Restrictive cardiomyopathy (RCM)+++H00292///Hypertrophic cardiomyopathy (HCM)",null,null,"GO:1990584///cardiac Troponin complex+++GO:0030016///myofibril+++GO:0005861///troponin complex+++GO:0005865///striated muscle thin filament+++GO:0097512///cardiac myofibril+++GO:0030017///sarcomere+++GO:0005829///cytosol","GO:0005509///calcium ion binding+++GO:0003779///actin binding+++GO:0031013///troponin I binding+++GO:0030172///troponin C binding+++GO:0005515///protein binding+++GO:0005523///tropomyosin binding+++GO:0016887///ATPase activity+++GO:0030674///protein binding, bridging+++GO:0030899///calcium-dependent ATPase activity","GO:0051764///actin crosslink formation+++GO:0008016///regulation of heart contraction+++GO:0051592///response to calcium ion+++GO:0030049///muscle filament sliding+++GO:0003009///skeletal muscle contraction+++GO:0032972///regulation of muscle filament sliding speed+++GO:0032781///positive regulation of ATPase activity+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0045214///sarcomere organization+++GO:0060048///cardiac muscle contraction+++GO:0032780///negative regulation of ATPase activity+++GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0051291///protein heterooligomerization","troponin T2, cardiac type","[TNNT2_HUMAN|Reviewed]RecName: Full=Troponin T, cardiac muscle; Short=TnTc; AltName: Full=Cardiac muscle troponin T; Short=cTnT;+++[A0A024R953_HUMAN|Unreviewed]SubName: Full=Troponin T type 2 (Cardiac), isoform CRA_a {ECO:0000313|EMBL:EAW91362.1};+++[A0A0A0MRJ4_HUMAN|Unreviewed]SubName: Full=Troponin T, cardiac muscle {ECO:0000313|Ensembl:ENSP00000356284};+++[A0A0A0MRJ5_HUMAN|Unreviewed]SubName: Full=Troponin T, cardiac muscle {ECO:0000313|Ensembl:ENSP00000356286};+++[A9QLG1_HUMAN|Unreviewed]SubName: Full=Troponin T type 2 cardiac {ECO:0000313|EMBL:ABV48784.1}; Flags: Fragment;+++[A9QLG2_HUMAN|Unreviewed]SubName: Full=Troponin T type 2 cardiac {ECO:0000313|EMBL:ABV48785.1}; Flags: Fragment;+++[C9JDF8_HUMAN|Unreviewed]SubName: Full=Troponin T, cardiac muscle {ECO:0000313|Ensembl:ENSP00000395163}; Flags: Fragment;+++[C9JM61_HUMAN|Unreviewed]SubName: Full=Troponin T, cardiac muscle {ECO:0000313|Ensembl:ENSP00000408731}; Flags: Fragment;+++[E7EPN8_HUMAN|Unreviewed]SubName: Full=Troponin T, cardiac muscle {ECO:0000313|Ensembl:ENSP00000402238}; Flags: Fragment;+++[E7EPW4_HUMAN|Unreviewed]SubName: Full=Troponin T, cardiac muscle {ECO:0000313|Ensembl:ENSP00000414036}; Flags: Fragment;+++[Q15607_HUMAN|Unreviewed]SubName: Full=Cardiac troponin T {ECO:0000313|EMBL:CAA56240.1}; Flags: Fragment;+++[Q7Z554_HUMAN|Unreviewed]SubName: Full=Troponin T cardiac isoform {ECO:0000313|EMBL:AAP96757.1}; SubName: Full=Troponin T type 2 (Cardiac), isoform CRA_b {ECO:0000313|EMBL:EAW91354.1}; SubName: Full=Troponin T, cardiac muscle {ECO:0000313|Ensembl:ENSP00000387874};+++[Q8IZA1_HUMAN|Unreviewed]SubName: Full=Cardiac troponin T {ECO:0000313|EMBL:AAN71651.1}; SubName: Full=Troponin T type 2 cardiac {ECO:0000313|EMBL:ABV48786.1}; Flags: Fragment;+++[Q8IZA2_HUMAN|Unreviewed]SubName: Full=Cardiac troponin T {ECO:0000313|EMBL:AAN71650.1}; Flags: Fragment;"]
[7165,"'TPD52L2'",2063,2530,2452,2348.33333333333,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm","GO:0003824///catalytic activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity","GO:0042127///regulation of cell proliferation","TPD52 like 2","[TPD54_HUMAN|Reviewed]RecName: Full=Tumor protein D54; Short=hD54; AltName: Full=Tumor protein D52-like 2;+++[A0A087WYR3_HUMAN|Unreviewed]SubName: Full=Tumor protein D54 {ECO:0000313|Ensembl:ENSP00000482024};+++[A0A087WZ51_HUMAN|Unreviewed]SubName: Full=Tumor protein D54 {ECO:0000313|Ensembl:ENSP00000482370};+++[Q68E05_HUMAN|Unreviewed]SubName: Full=Tumor protein D52-like 2, isoform CRA_f {ECO:0000313|EMBL:EAW75200.1}; SubName: Full=cDNA FLJ54053, highly similar to Homo sapiens tumor protein D52-like 2 (TPD52L2), transcript variant 6, mRNA {ECO:0000313|EMBL:BAG59585.1};+++[Q6FGS1_HUMAN|Unreviewed]SubName: Full=TPD52L2 protein {ECO:0000313|EMBL:CAG46833.1}; SubName: Full=Tumor protein D52-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW75194.1}; SubName: Full=cDNA, FLJ95317, highly similar to Homo sapiens tumor protein D52-like 2 (TPD52L2), mRNA {ECO:0000313|EMBL:BAG37101.1};"]
[7181,"'NR2C1'",275,296,240,270.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016605///PML body","GO:0038023///signaling receptor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0042826///histone deacetylase binding+++GO:0003707///steroid hormone receptor activity+++GO:0042803///protein homodimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043401///steroid hormone mediated signaling pathway","nuclear receptor subfamily 2 group C member 1","[NR2C1_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 2 group C member 1; AltName: Full=Orphan nuclear receptor TR2; AltName: Full=Testicular receptor 2;+++[A0A087WUK4_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2 group C member 1 {ECO:0000313|Ensembl:ENSP00000478728};+++[B6ZGT7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2, group C isoform {ECO:0000313|EMBL:BAH02298.1};+++[F8W1Q1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2 group C member 1 {ECO:0000313|Ensembl:ENSP00000446906}; Flags: Fragment;+++[H0YHC6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2 group C member 1 {ECO:0000313|Ensembl:ENSP00000446817}; Flags: Fragment;+++[H0YIV1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2 group C member 1 {ECO:0000313|Ensembl:ENSP00000450225}; Flags: Fragment;+++[H9NIM2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 2, group C, member 1, isoform CRA_c {ECO:0000313|EMBL:EAW97519.1}; SubName: Full=Testicular nuclear receptor 2 variant 1 {ECO:0000313|EMBL:AFF59487.1};+++[H9NIM3_HUMAN|Unreviewed]SubName: Full=Testicular nuclear receptor 2 variant 2 {ECO:0000313|EMBL:AFF59488.1};"]
[722,"'C4BPA'",0,0,1,0.333333333333333,"05133///Pertussis+++04610///Complement and coagulation cascades","H00106///Complement regulatory protein defects",null,null,"GO:0005576///extracellular region+++GO:0072562///blood microparticle+++GO:0005615///extracellular space+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:1903027///regulation of opsonization+++GO:0045087///innate immune response+++GO:0045732///positive regulation of protein catabolic process+++GO:0030449///regulation of complement activation+++GO:0002376///immune system process+++GO:0045959///negative regulation of complement activation, classical pathway+++GO:0006958///complement activation, classical pathway","complement component 4 binding protein alpha","[C4BPA_HUMAN|Reviewed]RecName: Full=C4b-binding protein alpha chain; Short=C4bp; AltName: Full=Proline-rich protein; Short=PRP; Flags: Precursor;+++[A6PVY5_HUMAN|Unreviewed]SubName: Full=C4b-binding protein alpha chain {ECO:0000313|Ensembl:ENSP00000403386}; Flags: Fragment;+++[F2Z2V7_HUMAN|Unreviewed]SubName: Full=C4b-binding protein alpha chain {ECO:0000313|Ensembl:ENSP00000395968};"]
[7259,"'TSPYL1'",2087.02,2182,1994.93,2087.98333333333,null,"H00607///46,XY disorders of sex development (Disorders of gonadal development)",null,null,"GO:0005622///intracellular+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0019899///enzyme binding","GO:0008150///biological_process+++GO:0006334///nucleosome assembly","TSPY like 1","[TSYL1_HUMAN|Reviewed]RecName: Full=Testis-specific Y-encoded-like protein 1; Short=TSPY-like protein 1;+++[Q6FI91_HUMAN|Unreviewed]SubName: Full=TSPYL protein {ECO:0000313|EMBL:CAG38566.1};"]
[727800,"'RNF208'",465,545,573,527.666666666667,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:0051865///protein autoubiquitination","ring finger protein 208","[RN208_HUMAN|Reviewed]RecName: Full=RING finger protein 208;"]
[728113,"'ANXA8L1'",382.12,655.21,575.21,537.513333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0031902///late endosome membrane+++GO:0005623///cell+++GO:0062023///collagen-containing extracellular matrix+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0051015///actin filament binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding","GO:0016197///endosomal transport+++GO:0007596///blood coagulation+++GO:0007032///endosome organization+++GO:1900138///negative regulation of phospholipase A2 activity+++GO:1900004///negative regulation of serine-type endopeptidase activity+++GO:0007599///hemostasis","annexin A8 like 1","[ANXA8_HUMAN|Reviewed]RecName: Full=Annexin A8 {ECO:0000312|HGNC:HGNC:546}; AltName: Full=Annexin VIII {ECO:0000303|PubMed:1313714}; AltName: Full=Annexin-8 {ECO:0000303|PubMed:2530088}; AltName: Full=Vascular anticoagulant-beta {ECO:0000303|PubMed:2530088}; Short=VAC-beta {ECO:0000303|PubMed:2530088};+++[AXA81_HUMAN|Reviewed]RecName: Full=Annexin A8-like protein 1 {ECO:0000305};+++[A0A075B748_HUMAN|Unreviewed]SubName: Full=Annexin A8 {ECO:0000313|Ensembl:ENSP00000462181};+++[A0A075B752_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[A0A075B765_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[A0A087WUP0_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[B4DTF2_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};+++[Q5T2P7_HUMAN|Unreviewed]RecName: Full=Annexin {ECO:0000256|RuleBase:RU003540};"]
[728194,"'RSPH10B2'",0,6,2.87,2.95666666666667,"03460///Fanconi anemia pathway+++03430///Mismatch repair","H00876///Mismatch repair deficiency","M00295///BRCA1-associated genome surveillance complex (BASC)",null,"GO:0005886///plasma membrane+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0015630///microtubule cytoskeleton+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0032389///MutLalpha complex+++GO:0005765///lysosomal membrane+++GO:0016235///aggresome+++GO:0031982///vesicle+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle","GO:0004519///endonuclease activity+++GO:0005524///ATP binding+++GO:0032138///single base insertion or deletion binding+++GO:0003677///DNA binding+++GO:0016887///ATPase activity","GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0042493///response to drug+++GO:0006298///mismatch repair+++GO:0016192///vesicle-mediated transport","radial spoke head 10 homolog B2","[R10B2_HUMAN|Reviewed]RecName: Full=Radial spoke head 10 homolog B2;+++[A0A1D5RMP1_HUMAN|Unreviewed]SubName: Full=Radial spoke head 10 homolog B2 {ECO:0000313|Ensembl:ENSP00000396498}; Flags: Fragment;+++[C9JJN2_HUMAN|Unreviewed]SubName: Full=Radial spoke head 10 homolog B2 {ECO:0000313|Ensembl:ENSP00000395335}; Flags: Fragment;+++[H0YFY2_HUMAN|Unreviewed]SubName: Full=Radial spoke head 10 homolog B2 {ECO:0000313|Ensembl:ENSP00000445255}; Flags: Fragment;"]
[728568,"'C12orf73'",54,55,53,54,"04915///Estrogen signaling pathway+++04151///PI3K-Akt signaling pathway+++04626///Plant-pathogen interaction+++05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04918///Thyroid hormone synthesis+++04657///IL-17 signaling pathway+++04141///Protein processing in endoplasmic reticulum+++05215///Prostate cancer",{"$nulls":3},"GO:0005576///extracellular region","GO:0019903///protein phosphatase binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0051082///unfolded protein binding+++GO:0050750///low-density lipoprotein particle receptor binding","GO:0043066///negative regulation of apoptotic process+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0001666///response to hypoxia+++GO:0036500///ATF6-mediated unfolded protein response+++GO:0043687///post-translational protein modification+++GO:0031247///actin rod assembly+++GO:0002224///toll-like receptor signaling pathway+++GO:0030970///retrograde protein transport, ER to cytosol+++GO:0034976///response to endoplasmic reticulum stress+++GO:0044267///cellular protein metabolic process+++GO:0051208///sequestering of calcium ion+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0006898///receptor-mediated endocytosis+++GO:0015031///protein transport+++GO:0071318///cellular response to ATP","chromosome 12 open reading frame 73","[CL073_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C12orf73; Flags: Precursor;+++[F8VQR3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf73 {ECO:0000313|Ensembl:ENSP00000450253};+++[F8VS87_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf73 {ECO:0000313|Ensembl:ENSP00000447827};+++[F8VXG8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf73 {ECO:0000313|Ensembl:ENSP00000448863};+++[G3V1W1_HUMAN|Unreviewed]SubName: Full=HCG21868, isoform CRA_a {ECO:0000313|EMBL:EAW97725.1};"]
[728642,"'CDK11A'",601.79,650.83,711.22,654.613333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity","GO:0001558///regulation of cell growth+++GO:0051301///cell division+++GO:0006915///apoptotic process+++GO:0050684///regulation of mRNA processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle","cyclin dependent kinase 11A","[CD11A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 11A; EC=2.7.11.22; AltName: Full=Cell division cycle 2-like protein kinase 2; AltName: Full=Cell division protein kinase 11A; AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA; AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L2;+++[A0A024R065_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2-like 2 (PITSLRE proteins), isoform CRA_a {ECO:0000313|EMBL:EAW56167.1}; Flags: Fragment;+++[A0A024R0C4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2-like 2 (PITSLRE proteins), isoform CRA_b {ECO:0000313|EMBL:EAW56168.1}; Flags: Fragment;+++[A0A1B0GYL8_HUMAN|Unreviewed]SubName: Full=PITSLRE protein kinase beta SV15 isoform {ECO:0000313|EMBL:AAC95301.1}; Flags: Fragment;+++[A0A1B0H6K7_HUMAN|Unreviewed]SubName: Full=PITSLRE protein kinase beta SV18 isoform {ECO:0000313|EMBL:AAC95304.1}; Flags: Fragment;+++[E7ESP2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11A {ECO:0000313|Ensembl:ENSP00000422149};+++[E9PFJ2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11A {ECO:0000313|Ensembl:ENSP00000423900}; Flags: Fragment;+++[J3KS35_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11A {ECO:0000313|Ensembl:ENSP00000462289};+++[Q05C84_HUMAN|Unreviewed]SubName: Full=CDC2L2 protein {ECO:0000313|EMBL:AAH28187.1}; Flags: Fragment;+++[Q3SWV2_HUMAN|Unreviewed]SubName: Full=CDC2L2 protein {ECO:0000313|EMBL:AAI04662.1}; Flags: Fragment;+++[Q4VBY6_HUMAN|Unreviewed]SubName: Full=CDC2L2 protein {ECO:0000313|EMBL:AAH94827.1}; Flags: Fragment;+++[Q5QPQ9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11A {ECO:0000313|Ensembl:ENSP00000383874}; Flags: Fragment;+++[Q5QPR3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11A {ECO:0000313|Ensembl:ENSP00000350403};+++[Q5QPR4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11A {ECO:0000313|Ensembl:ENSP00000367905};+++[Q6P5Y5_HUMAN|Unreviewed]SubName: Full=CDC2L2 protein {ECO:0000313|EMBL:AAH62579.1}; Flags: Fragment;+++[Q96CA8_HUMAN|Unreviewed]SubName: Full=CDC2L2 protein {ECO:0000313|EMBL:AAH14464.1}; Flags: Fragment;"]
[729220,"'FLJ45513'",0,2,0,0.666666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005623///cell+++GO:0005615///extracellular space","GO:0005102///signaling receptor binding+++GO:0031835///substance P receptor binding+++GO:0048018///receptor ligand activity+++GO:0031837///substance K receptor binding","GO:0007217///tachykinin receptor signaling pathway+++GO:1904057///negative regulation of sensory perception of pain+++GO:0050965///detection of temperature stimulus involved in sensory perception of pain+++GO:0051930///regulation of sensory perception of pain+++GO:0006954///inflammatory response+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:1904058///positive regulation of sensory perception of pain+++GO:1902093///positive regulation of flagellated sperm motility+++GO:0007267///cell-cell signaling+++GO:0008217///regulation of blood pressure+++GO:0003085///negative regulation of systemic arterial blood pressure","uncharacterized LOC729220","[Q6ZSH9_HUMAN|Unreviewed]SubName: Full=HCG2045601 {ECO:0000313|EMBL:EAW94656.1}; SubName: Full=cDNA FLJ45513 fis, clone BRTHA2021450 {ECO:0000313|EMBL:BAC86972.1};"]
[729438,"'CASTOR2'",729,695.01,598.01,674.006666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0061700///GATOR2 complex+++GO:0005737///cytoplasm","GO:0034618///arginine binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:1904262///negative regulation of TORC1 signaling+++GO:1903577///cellular response to L-arginine+++GO:1902531///regulation of intracellular signal transduction","cytosolic arginine sensor for mTORC1 subunit 2","[CAST2_HUMAN|Reviewed]RecName: Full=Cytosolic arginine sensor for mTORC1 subunit 2 {ECO:0000312|HGNC:HGNC:37073}; AltName: Full=Cellular arginine sensor for mTORC1 protein 2 {ECO:0000305|PubMed:26972053}; AltName: Full=GATS-like protein 2 {ECO:0000305};"]
[730,"'C7'",4,2,0,2,"05020///Prion diseases+++04610///Complement and coagulation cascades+++05322///Systemic lupus erythematosus","H00103///Late complement pathway defects",null,null,"GO:0005579///membrane attack complex+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region",null,"GO:0006883///cellular sodium ion homeostasis+++GO:0006957///complement activation, alternative pathway+++GO:0030449///regulation of complement activation+++GO:0019835///cytolysis+++GO:0006956///complement activation+++GO:0006958///complement activation, classical pathway","complement C7","[CO7_HUMAN|Reviewed]RecName: Full=Complement component C7; Flags: Precursor;+++[Q05CI3_HUMAN|Unreviewed]SubName: Full=C7 protein {ECO:0000313|EMBL:AAH25402.1}; Flags: Fragment;"]
[730130,"'TMEM229A'",72,34,57,54.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003964///RNA-directed DNA polymerase activity",null,"transmembrane protein 229A","[T229A_HUMAN|Reviewed]RecName: Full=Transmembrane protein 229A;"]
[7321,"'UBE2D1'",323,380,339,347.333333333333,"04624///Toll and Imd signaling pathway+++04120///Ubiquitin mediated proteolysis+++04013///MAPK signaling pathway - fly+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0031625///ubiquitin protein ligase binding","GO:0030509///BMP signaling pathway+++GO:0070936///protein K48-linked ubiquitination+++GO:0000209///protein polyubiquitination+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0016567///protein ubiquitination+++GO:0016579///protein deubiquitination+++GO:0006625///protein targeting to peroxisome+++GO:0031398///positive regulation of protein ubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1901990///regulation of mitotic cell cycle phase transition","ubiquitin conjugating enzyme E2 D1","[UB2D1_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 D1; EC=2.3.2.23 {ECO:0000269|PubMed:18042044, ECO:0000269|PubMed:19854139, ECO:0000269|PubMed:20061386}; AltName: Full=(E3-independent) E2 ubiquitin-conjugating enzyme D1; EC=2.3.2.24 {ECO:0000269|PubMed:17588522}; AltName: Full=E2 ubiquitin-conjugating enzyme D1; AltName: Full=Stimulator of Fe transport; Short=SFT; AltName: Full=UBC4/5 homolog; AltName: Full=UbcH5; AltName: Full=Ubiquitin carrier protein D1; AltName: Full=Ubiquitin-conjugating enzyme E2(17)KB 1; AltName: Full=Ubiquitin-conjugating enzyme E2-17 kDa 1; AltName: Full=Ubiquitin-protein ligase D1;+++[A0A024QZJ2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast), isoform CRA_c {ECO:0000313|EMBL:EAW54170.1};+++[A0A087WW00_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 D1 {ECO:0000313|Ensembl:ENSP00000479814};"]
[7329,"'UBE2I'",1645,1862,1750,1752.33333333333,"04120///Ubiquitin mediated proteolysis+++03013///RNA transport+++04064///NF-kappa B signaling pathway+++05206///MicroRNAs in cancer",null,"M00427///Nuclear pore complex",null,"GO:1990234///transferase complex+++GO:0030425///dendrite+++GO:0005635///nuclear envelope+++GO:0045202///synapse+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000795///synaptonemal complex+++GO:0001650///fibrillar center+++GO:1990356///sumoylated E2 ligase complex+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0016605///PML body","GO:0043425///bHLH transcription factor binding+++GO:0043398///HLH domain binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0061656///SUMO conjugating enzyme activity+++GO:0019789///SUMO transferase activity+++GO:0005515///protein binding+++GO:0044388///small protein activating enzyme binding+++GO:0008022///protein C-terminus binding+++GO:0019899///enzyme binding+++GO:0071535///RING-like zinc finger domain binding","GO:0016567///protein ubiquitination+++GO:0016032///viral process+++GO:0006464///cellular protein modification process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0033145///positive regulation of intracellular steroid hormone receptor signaling pathway+++GO:0016925///protein sumoylation+++GO:1903755///positive regulation of SUMO transferase activity+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010469///regulation of signaling receptor activity+++GO:0051301///cell division","ubiquitin conjugating enzyme E2 I","[UBC9_HUMAN|Reviewed]RecName: Full=SUMO-conjugating enzyme UBC9; EC=2.3.2.- {ECO:0000269|PubMed:26524494}; AltName: Full=RING-type E3 SUMO transferase UBC9; AltName: Full=SUMO-protein ligase; AltName: Full=Ubiquitin carrier protein 9; AltName: Full=Ubiquitin carrier protein I; AltName: Full=Ubiquitin-conjugating enzyme E2 I; AltName: Full=Ubiquitin-protein ligase I; AltName: Full=p18;+++[A8K503_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76182, highly similar to Homo sapiens ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) (UBE2I), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF83807.1};+++[B0QYN7_HUMAN|Unreviewed]SubName: Full=SUMO-conjugating enzyme UBC9 {ECO:0000313|Ensembl:ENSP00000384361};+++[H3BPC4_HUMAN|Unreviewed]SubName: Full=SUMO-conjugating enzyme UBC9 {ECO:0000313|Ensembl:ENSP00000455252}; Flags: Fragment;+++[H3BQQ9_HUMAN|Unreviewed]SubName: Full=SUMO-conjugating enzyme UBC9 {ECO:0000313|Ensembl:ENSP00000455893}; Flags: Fragment;+++[H3BRD1_HUMAN|Unreviewed]SubName: Full=SUMO-conjugating enzyme UBC9 {ECO:0000313|Ensembl:ENSP00000456188}; Flags: Fragment;+++[Q7KZS0_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast), isoform CRA_b {ECO:0000313|EMBL:EAW85674.1};"]
[7371,"'UCK2'",288,270,360,306,"00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01100///Metabolic pathways",null,null,"R02372///dUTP:cytidine 5'-phosphotransferase   dUTP + Cytidine <=> dUDP + CMP+++R01880///dGTP:uridine 5'-phosphotransferase   dGTP + Uridine <=> dGDP + UMP+++R01549///dATP:uridine 5'-phosphotransferase   dATP + Uridine <=> dADP + UMP+++R00516///UTP:cytidine 5'-phosphotransferase   UTP + Cytidine <=> UDP + CMP+++R02096///dTTP:cytidine 5'-phosphotransferase   dTTP + Cytidine <=> dTDP + CMP+++R00964///ATP:uridine 5'-phosphotransferase   ATP + Uridine <=> ADP + UMP+++R08232///ATP:5-fluorouridine 5'-phosphotransferase   5-Fluorouridine + ATP <=> 5-Fluorouridine monophosphate + ADP+++R01548///dATP:cytidine 5'-phosphotransferase   dATP + Cytidine <=> dADP + CMP+++R02097///dTTP:uridine 5'-phosphotransferase   dTTP + Uridine <=> dTDP + UMP+++R00970///ITP:uridine 5'-phosphotransferase   ITP + Uridine <=> IDP + UMP+++R00962///ITP:cytidine 5'-phosphotransferase   ITP + Cytidine <=> IDP + CMP+++R00967///UTP:uridine 5'-phosphotransferase   UTP + Uridine <=> UDP + UMP+++R00968///GTP:uridine 5'-phosphotransferase   GTP + Uridine <=> GDP + UMP+++R02371///dCTP:cytidine 5'-phosphotransferase   dCTP + Cytidine <=> dCDP + CMP+++R00513///ATP:cytidine 5'-phosphotransferase   ATP + Cytidine <=> ADP + CMP+++R00517///GTP:cytidine 5'-phosphotransferase   GTP + Cytidine <=> GDP + CMP+++R02332///dUTP:uridine 5'-phosphotransferase   dUTP + Uridine <=> dUDP + UMP+++R02091///dGTP:cytidine 5'-phosphotransferase   dGTP + Cytidine <=> dGDP + CMP+++R02327///dCTP:uridine 5'-phosphotransferase   dCTP + Uridine <=> dCDP + UMP","GO:0005575///cellular_component+++GO:0005829///cytosol","GO:0005524///ATP binding+++GO:0004849///uridine kinase activity+++GO:0019206///nucleoside kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding","GO:0016310///phosphorylation+++GO:0006238///CMP salvage+++GO:0043097///pyrimidine nucleoside salvage+++GO:0044211///CTP salvage+++GO:0044206///UMP salvage","uridine-cytidine kinase 2","[UCK2_HUMAN|Reviewed]RecName: Full=Uridine-cytidine kinase 2; Short=UCK 2; EC=2.7.1.48; AltName: Full=Cytidine monophosphokinase 2; AltName: Full=Testis-specific protein TSA903; AltName: Full=Uridine monophosphokinase 2;+++[A0A024R912_HUMAN|Unreviewed]RecName: Full=Uridine-cytidine kinase {ECO:0000256|RuleBase:RU003825}; EC=2.7.1.48 {ECO:0000256|RuleBase:RU003825};+++[A0A2R8Y653_HUMAN|Unreviewed]SubName: Full=Uridine-cytidine kinase 2 {ECO:0000313|Ensembl:ENSP00000494961};"]
[7379,"'UPK2'",19,20,14,17.6666666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane","GO:0005515///protein binding","GO:0030855///epithelial cell differentiation+++GO:0007275///multicellular organism development","uroplakin 2","[UPK2_HUMAN|Reviewed]RecName: Full=Uroplakin-2; Short=UP2; AltName: Full=Uroplakin II; Short=UPII; Flags: Precursor;"]
[7412,"'VCAM1'",0,0,1,0.333333333333333,"04514///Cell adhesion molecules (CAMs)+++05418///Fluid shear stress and atherosclerosis+++04064///NF-kappa B signaling pathway+++05166///HTLV-I infection+++05143///African trypanosomiasis+++05144///Malaria+++04670///Leukocyte transendothelial migration+++04933///AGE-RAGE signaling pathway in diabetic complications+++04668///TNF signaling pathway",{"$nulls":3},"GO:0002102///podosome+++GO:0005902///microvillus+++GO:0005794///Golgi apparatus+++GO:0005769///early endosome+++GO:0016021///integral component of membrane+++GO:0071065///alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0042383///sarcolemma+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0030175///filopodium+++GO:0045177///apical part of cell+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0009897///external side of plasma membrane","GO:0050839///cell adhesion molecule binding+++GO:0005178///integrin binding+++GO:0008131///primary amine oxidase activity","GO:0098609///cell-cell adhesion+++GO:0042102///positive regulation of T cell proliferation+++GO:0030198///extracellular matrix organization+++GO:0060384///innervation+++GO:0060326///cell chemotaxis+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0060945///cardiac neuron differentiation+++GO:0007159///leukocyte cell-cell adhesion+++GO:0007155///cell adhesion+++GO:0002526///acute inflammatory response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0071356///cellular response to tumor necrosis factor+++GO:0050776///regulation of immune response+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0010212///response to ionizing radiation+++GO:0001666///response to hypoxia+++GO:0022614///membrane to membrane docking+++GO:0007568///aging+++GO:0007160///cell-matrix adhesion+++GO:0045471///response to ethanol+++GO:0035094///response to nicotine+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0010043///response to zinc ion+++GO:0055114///oxidation-reduction process+++GO:0007584///response to nutrient+++GO:0009308///amine metabolic process+++GO:0050901///leukocyte tethering or rolling+++GO:0002544///chronic inflammatory response","vascular cell adhesion molecule 1","[VCAM1_HUMAN|Reviewed]RecName: Full=Vascular cell adhesion protein 1; Short=V-CAM 1; Short=VCAM-1; AltName: Full=INCAM-100; AltName: CD_antigen=CD106; Flags: Precursor;+++[E9PDD2_HUMAN|Unreviewed]SubName: Full=Vascular cell adhesion protein 1 {ECO:0000313|Ensembl:ENSP00000359133};+++[F2YYR6_HUMAN|Unreviewed]SubName: Full=Vascular cell adhesion molecule 1 {ECO:0000313|EMBL:ADZ72971.1}; Flags: Fragment;+++[F8UU18_HUMAN|Unreviewed]SubName: Full=Vascular cell adhesion molecule 1 {ECO:0000313|EMBL:AEH21939.1}; Flags: Fragment;+++[F8UV74_HUMAN|Unreviewed]SubName: Full=Vascular cell adhesion molecule 1 {ECO:0000313|EMBL:AEH21940.1}; Flags: Fragment;+++[G0ZFQ0_HUMAN|Unreviewed]SubName: Full=Vascular cell adhesion molecule 1 {ECO:0000313|EMBL:AEL30503.1}; Flags: Fragment;+++[G0ZI12_HUMAN|Unreviewed]SubName: Full=Vascular cell adhesion molecule 1 {ECO:0000313|EMBL:AEL21381.1}; Flags: Fragment;"]
[7419,"'VDAC3'",676,670,617,654.333333333333,"04022///cGMP-PKG signaling pathway+++04217///Necroptosis+++05166///HTLV-I infection+++04979///Cholesterol metabolism+++05012///Parkinson's disease+++04216///Ferroptosis+++04020///Calcium signaling pathway+++05203///Viral carcinogenesis+++04621///NOD-like receptor signaling pathway+++05161///Hepatitis B+++05016///Huntington's disease+++04218///Cellular senescence",{"$nulls":3},"GO:0046930///pore complex+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005741///mitochondrial outer membrane+++GO:0070062///extracellular exosome","GO:0008308///voltage-gated anion channel activity+++GO:0015288///porin activity+++GO:0000166///nucleotide binding","GO:0007270///neuron-neuron synaptic transmission+++GO:1902017///regulation of cilium assembly+++GO:0007612///learning+++GO:0001662///behavioral fear response+++GO:0015853///adenine transport","voltage dependent anion channel 3","[VDAC3_HUMAN|Reviewed]RecName: Full=Voltage-dependent anion-selective channel protein 3; Short=VDAC-3; Short=hVDAC3; AltName: Full=Outer mitochondrial membrane protein porin 3;"]
[7462,"'LAT2'",6,17,6,9.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0042629///mast cell granule+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome","GO:0042169///SH2 domain binding","GO:0019722///calcium-mediated signaling+++GO:0002250///adaptive immune response+++GO:0042113///B cell activation+++GO:0043303///mast cell degranulation+++GO:0035556///intracellular signal transduction+++GO:0050853///B cell receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway","linker for activation of T cells family member 2","[NTAL_HUMAN|Reviewed]RecName: Full=Linker for activation of T-cells family member 2; AltName: Full=Linker for activation of B-cells; AltName: Full=Membrane-associated adapter molecule; AltName: Full=Non-T-cell activation linker; AltName: Full=Williams-Beuren syndrome chromosomal region 15 protein; AltName: Full=Williams-Beuren syndrome chromosomal region 5 protein;"]
[7468,"'NSD2'",761,765,569,698.333333333333,"00310///Lysine degradation+++05202///Transcriptional misregulation in cancer","H01773///4p deletion syndrome+++H00010///Multiple myeloma",null,"R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005694///chromosome","GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0042799///histone methyltransferase activity (H4-K20 specific)+++GO:0016740///transferase activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0003149///membranous septum morphogenesis+++GO:0006325///chromatin organization+++GO:0032259///methylation+++GO:0010452///histone H3-K36 methylation+++GO:0048298///positive regulation of isotype switching to IgA isotypes+++GO:0003290///atrial septum secundum morphogenesis+++GO:0070201///regulation of establishment of protein localization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060348///bone development+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining+++GO:0003289///atrial septum primum morphogenesis+++GO:0034770///histone H4-K20 methylation+++GO:0006303///double-strand break repair via nonhomologous end joining","nuclear receptor binding SET domain protein 2","[NSD2_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase NSD2; EC=2.1.1.43; AltName: Full=Multiple myeloma SET domain-containing protein; Short=MMSET; AltName: Full=Nuclear SET domain-containing protein 2; AltName: Full=Protein trithorax-5; AltName: Full=Wolf-Hirschhorn syndrome candidate 1 protein;+++[D6R9V2_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase NSD2 {ECO:0000313|Ensembl:ENSP00000422878}; Flags: Fragment;+++[D6RFE7_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase NSD2 {ECO:0000313|Ensembl:ENSP00000421551}; Flags: Fragment;+++[D6RIS1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase NSD2 {ECO:0000313|Ensembl:ENSP00000427434}; Flags: Fragment;+++[H0Y9L4_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase NSD2 {ECO:0000313|Ensembl:ENSP00000424482}; Flags: Fragment;+++[H0Y9U6_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase NSD2 {ECO:0000313|Ensembl:ENSP00000425094}; Flags: Fragment;+++[L0R6U5_HUMAN|Unreviewed]SubName: Full=Alternative protein WHSC1 {ECO:0000313|EMBL:CCO13850.1};+++[Q05CW4_HUMAN|Unreviewed]SubName: Full=WHSC1 protein {ECO:0000313|EMBL:AAH20545.1};"]
[7486,"'WRN'",129,115,99,114.333333333333,null,"H01733///Werner syndrome+++H00296///Defects in RecQ helicases",null,null,"GO:0000781///chromosome, telomeric region+++GO:0005657///replication fork+++GO:0005662///DNA replication factor A complex+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm+++GO:0032389///MutLalpha complex+++GO:0043005///neuron projection+++GO:0005813///centrosome+++GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0005694///chromosome+++GO:0005654///nucleoplasm","GO:0032405///MutLalpha complex binding+++GO:0043140///ATP-dependent 3'-5' DNA helicase activity+++GO:0000405///bubble DNA binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0003678///DNA helicase activity+++GO:0051880///G-quadruplex DNA binding+++GO:0005524///ATP binding+++GO:0000403///Y-form DNA binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0061749///forked DNA-dependent helicase activity+++GO:0061849///telomeric G-quadruplex DNA binding+++GO:0008026///ATP-dependent helicase activity+++GO:0004386///helicase activity+++GO:0043138///3'-5' DNA helicase activity+++GO:0042803///protein homodimerization activity+++GO:0030145///manganese ion binding+++GO:0000287///magnesium ion binding+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0009378///four-way junction helicase activity+++GO:0004527///exonuclease activity+++GO:0004518///nuclease activity+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000400///four-way junction DNA binding+++GO:0008408///3'-5' exonuclease activity+++GO:1905773///8-hydroxy-2'-deoxyguanosine DNA binding+++GO:0070337///3'-flap-structured DNA binding+++GO:0044877///protein-containing complex binding+++GO:0061821///telomeric D-loop binding","GO:0098530///positive regulation of strand invasion+++GO:0006259///DNA metabolic process+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0006260///DNA replication+++GO:0000723///telomere maintenance+++GO:0006284///base-excision repair+++GO:1902570///protein localization to nucleolus+++GO:0006310///DNA recombination+++GO:0044806///G-quadruplex DNA unwinding+++GO:0006302///double-strand break repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0008152///metabolic process+++GO:0008340///determination of adult lifespan+++GO:0032508///DNA duplex unwinding+++GO:0009267///cellular response to starvation+++GO:0006281///DNA repair+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0071480///cellular response to gamma radiation+++GO:0010259///multicellular organism aging+++GO:0051345///positive regulation of hydrolase activity+++GO:0007420///brain development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0061820///telomeric D-loop disassembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007569///cell aging+++GO:0001302///replicative cell aging+++GO:0090656///t-circle formation+++GO:0010225///response to UV-C+++GO:0044237///cellular metabolic process+++GO:0031297///replication fork processing+++GO:0042981///regulation of apoptotic process+++GO:0040009///regulation of growth rate+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","Werner syndrome RecQ like helicase","[WRN_HUMAN|Reviewed]RecName: Full=Werner syndrome ATP-dependent helicase; EC=3.6.4.12 {ECO:0000269|PubMed:16622405}; AltName: Full=DNA helicase, RecQ-like type 3; Short=RecQ3; AltName: Full=Exonuclease WRN; EC=3.1.-.-; AltName: Full=RecQ protein-like 2;"]
[7528,"'YY1'",1164,1275,1122,1187,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0031519///PcG protein complex+++GO:0005654///nucleoplasm+++GO:0031011///Ino80 complex+++GO:0005667///transcription factor complex+++GO:0000790///nuclear chromatin","GO:0003714///transcription corepressor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0000400///four-way junction DNA binding+++GO:0008270///zinc ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0042826///histone deacetylase binding+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0046332///SMAD binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity","GO:0034644///cellular response to UV+++GO:0006403///RNA localization+++GO:0010225///response to UV-C+++GO:0051276///chromosome organization+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0006310///DNA recombination+++GO:0032688///negative regulation of interferon-beta production+++GO:0034696///response to prostaglandin F+++GO:0010629///negative regulation of gene expression+++GO:0006281///DNA repair+++GO:0030154///cell differentiation+++GO:0071347///cellular response to interleukin-1+++GO:0000724///double-strand break repair via homologous recombination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0009952///anterior/posterior pattern specification+++GO:0007283///spermatogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016579///protein deubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:0048593///camera-type eye morphogenesis","YY1 transcription factor","[TYY1_HUMAN|Reviewed]RecName: Full=Transcriptional repressor protein YY1; AltName: Full=Delta transcription factor; AltName: Full=INO80 complex subunit S; AltName: Full=NF-E1; AltName: Full=Yin and yang 1; Short=YY-1;+++[G3V3M8_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor protein YY1 {ECO:0000313|Ensembl:ENSP00000451329}; Flags: Fragment;+++[H0YJU4_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor protein YY1 {ECO:0000313|Ensembl:ENSP00000452140}; Flags: Fragment;+++[H0YJV7_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor protein YY1 {ECO:0000313|Ensembl:ENSP00000452225}; Flags: Fragment;"]
[7543,"'ZFX'",247,244,211,234,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003713///transcription coactivator activity","GO:0060746///parental behavior+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0009791///post-embryonic development+++GO:0048599///oocyte development+++GO:0035264///multicellular organism growth+++GO:0001541///ovarian follicle development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007283///spermatogenesis+++GO:0007281///germ cell development+++GO:0009566///fertilization+++GO:0048872///homeostasis of number of cells+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein X-linked","[ZFX_HUMAN|Reviewed]RecName: Full=Zinc finger X-chromosomal protein;+++[A0A024RC04_HUMAN|Unreviewed]SubName: Full=Zinc finger protein, X-linked, isoform CRA_a {ECO:0000313|EMBL:EAW99015.1};+++[B7ZKJ5_HUMAN|Unreviewed]SubName: Full=ZFX protein {ECO:0000313|EMBL:AAI36309.1};+++[C9J682_HUMAN|Unreviewed]SubName: Full=Zinc finger X-chromosomal protein {ECO:0000313|Ensembl:ENSP00000411637}; Flags: Fragment;+++[C9JGU9_HUMAN|Unreviewed]SubName: Full=Zinc finger X-chromosomal protein {ECO:0000313|Ensembl:ENSP00000416298}; Flags: Fragment;+++[E9PEP7_HUMAN|Unreviewed]SubName: Full=Zinc finger X-chromosomal protein {ECO:0000313|Ensembl:ENSP00000343384};+++[L8E7U7_HUMAN|Unreviewed]SubName: Full=Alternative protein ZFX {ECO:0000313|EMBL:CCQ43214.1};+++[Q59EB9_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein variant {ECO:0000313|EMBL:BAD93129.1}; Flags: Fragment;+++[Q8NHZ1_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein isoform 5 {ECO:0000313|EMBL:AAM33387.1}; Flags: Fragment;+++[Q8NHZ2_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein {ECO:0000313|EMBL:AAM33386.1}; Flags: Fragment;+++[Q8NHZ3_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein {ECO:0000313|EMBL:AAM33385.1}; Flags: Fragment;+++[Q8NHZ4_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein {ECO:0000313|EMBL:AAM33384.1}; Flags: Fragment;+++[Q8NHZ5_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein {ECO:0000313|EMBL:AAM33383.1}; Flags: Fragment;+++[Q8WWU0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFX isoform 4 {ECO:0000313|EMBL:AAL67136.1}; Flags: Fragment;+++[Q8WXB7_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein {ECO:0000313|EMBL:AAL51084.1}; Flags: Fragment;+++[Q8WXB8_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein {ECO:0000313|EMBL:AAL51083.1}; Flags: Fragment;+++[Q8WXB9_HUMAN|Unreviewed]SubName: Full=X-linked zinc finger protein {ECO:0000313|EMBL:AAL51082.1}; Flags: Fragment;+++[Q9BYX9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZFX {ECO:0000313|EMBL:AAG38815.1}; Flags: Fragment;"]
[7568,"'ZNF20'",31,45,42,39.3333333333333,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated","zinc finger protein 20","[ZNF20_HUMAN|Reviewed]RecName: Full=Zinc finger protein 20; AltName: Full=Zinc finger protein KOX13;"]
[7587,"'ZNF37A'",333,316,292,313.666666666667,"00100///Steroid biosynthesis+++00140///Steroid hormone biosynthesis+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++04913///Ovarian steroidogenesis","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly","M00101///Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol","R04681///Estriol:NAD+ 17-oxidoreductase Estriol + NAD+ <=> 16alpha-Hydroxyestrone + NADH + H++++R08945///11beta,17beta-dihydroxy-4-androsten-3-one:NAD+ 17-oxidoreductase 11beta,17beta-Dihydroxy-4-androsten-3-one + NAD+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H++++R02352///Estradiol-17beta:NAD+ 17-oxidoreductase Estradiol-17beta + NAD+ <=> Estrone + NADH + H++++R07495///4alpha-methylzymosterol:NADP+ 3-oxidoreductase 3-Keto-4-methylzymosterol + NADPH + H+ <=> 4alpha-Methylzymosterol + NADP++++R02353///Estradiol-17beta:NADP+ 17-oxidoreductase Estradiol-17beta + NADP+ <=> Estrone + NADPH + H++++R08980///11beta,17beta-dihydroxy-4-androsten-3-one:NADP+ 17-oxidoreductase 11beta,17beta-Dihydroxy-4-androsten-3-one + NADP+ <=> 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H++++R04682///Estriol:NADP+ 17-oxidoreductase Estriol + NADP+ <=> 16alpha-Hydroxyestrone + NADPH + H+","GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 37A","[ZN37A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 37A; AltName: Full=Zinc finger protein KOX21;+++[A0A1B0GVV4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 37A {ECO:0000313|Ensembl:ENSP00000490669};"]
[7629,"'ZNF76'",475,493,407,458.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006359///regulation of transcription by RNA polymerase III+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","zinc finger protein 76","[ZNF76_HUMAN|Reviewed]RecName: Full=Zinc finger protein 76; AltName: Full=Zinc finger protein 523;+++[A0A024RCU3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 76 (Expressed in testis), isoform CRA_b {ECO:0000313|EMBL:EAX03818.1};+++[A0A024RCW5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 76 (Expressed in testis), isoform CRA_c {ECO:0000313|EMBL:EAX03817.1};+++[A0A024RD10_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 76 (Expressed in testis), isoform CRA_a {ECO:0000313|EMBL:EAX03820.1};+++[E7EX64_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 76 {ECO:0000313|Ensembl:ENSP00000419106}; Flags: Fragment;+++[F8W971_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 76 {ECO:0000313|Ensembl:ENSP00000229405};+++[H7C513_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 76 {ECO:0000313|Ensembl:ENSP00000418749}; Flags: Fragment;"]
[7681,"'MKRN3'",24,12,15,17,null,"H02018///Central precocious puberty",null,null,"GO:1990904///ribonucleoprotein complex","GO:0042802///identical protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0016567///protein ubiquitination","makorin ring finger protein 3","[MKRN3_HUMAN|Reviewed]RecName: Full=Probable E3 ubiquitin-protein ligase makorin-3; EC=2.3.2.27; AltName: Full=RING finger protein 63; AltName: Full=RING-type E3 ubiquitin transferase makorin-3 {ECO:0000305}; AltName: Full=Zinc finger protein 127;+++[H3BPL3_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase makorin-3 {ECO:0000313|Ensembl:ENSP00000455368};+++[H3BUZ8_HUMAN|Unreviewed]SubName: Full=Probable E3 ubiquitin-protein ligase makorin-3 {ECO:0000313|Ensembl:ENSP00000457884};+++[Q6NSB6_HUMAN|Unreviewed]SubName: Full=MKRN3 protein {ECO:0000313|EMBL:AAH70293.1}; SubName: Full=Probable E3 ubiquitin-protein ligase makorin-3 {ECO:0000313|Ensembl:ENSP00000456779};"]
[7702,"'ZNF143'",182,188,165,178.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006383///transcription by RNA polymerase III+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 143","[ZN143_HUMAN|Reviewed]RecName: Full=Zinc finger protein 143; AltName: Full=SPH-binding factor; AltName: Full=Selenocysteine tRNA gene transcription-activating factor; Short=hStaf;+++[C9J2G7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000392323}; Flags: Fragment;+++[C9JCG1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000395221}; Flags: Fragment;+++[C9JRS3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000388628}; Flags: Fragment;+++[C9JTC5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000409432}; Flags: Fragment;+++[E7EN86_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000299606};+++[E9PJF2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000433743}; Flags: Fragment;+++[E9PLN4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000433221}; Flags: Fragment;+++[E9PLS7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000431306};+++[E9PMY8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000434922}; Flags: Fragment;+++[E9PPB0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000434638}; Flags: Fragment;+++[E9PS81_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000435881}; Flags: Fragment;+++[H7C1P6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000401493}; Flags: Fragment;+++[Q9H176_HUMAN|Unreviewed]SubName: Full=ZNF143 protein {ECO:0000313|EMBL:CAC17610.1}; Flags: Fragment;+++[Q9H4D4_HUMAN|Unreviewed]SubName: Full=ZNF143 protein {ECO:0000313|EMBL:CAC14172.1}; Flags: Fragment;"]
[7733,"'ZNF180'",60,70,61,63.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 180","[ZN180_HUMAN|Reviewed]RecName: Full=Zinc finger protein 180; AltName: Full=HHZ168;+++[A0A0A0MP75_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 180 {ECO:0000313|Ensembl:ENSP00000468021};+++[G5E9B8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 180 {ECO:0000313|Ensembl:ENSP00000375818};+++[K7EMI5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 180 {ECO:0000313|Ensembl:ENSP00000466516};+++[K7EN00_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 180 {ECO:0000313|Ensembl:ENSP00000466726};+++[K7EQP0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 180 {ECO:0000313|Ensembl:ENSP00000467916}; Flags: Fragment;+++[K7ES30_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 180 {ECO:0000313|Ensembl:ENSP00000468523};"]
[7755,"'ZNF205'",346,391,405,380.666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0010729///positive regulation of hydrogen peroxide biosynthetic process+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 205","[ZN205_HUMAN|Reviewed]RecName: Full=Zinc finger protein 205; AltName: Full=Zinc finger protein 210;+++[C9JEY6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 205 {ECO:0000313|Ensembl:ENSP00000403306}; Flags: Fragment;+++[C9JS60_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 205 {ECO:0000313|Ensembl:ENSP00000394360}; Flags: Fragment;+++[I0J0A3_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor RhitH {ECO:0000313|EMBL:BAM10952.1};+++[I3L417_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 205 {ECO:0000313|Ensembl:ENSP00000460890}; Flags: Fragment;"]
[7776,"'ZNF236'",230,213,130,191,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071333///cellular response to glucose stimulus","zinc finger protein 236","[ZN236_HUMAN|Reviewed]RecName: Full=Zinc finger protein 236;+++[A0A2R8YCW3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 236 {ECO:0000313|Ensembl:ENSP00000494034}; Flags: Fragment;+++[J3QQL1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 236 {ECO:0000313|Ensembl:ENSP00000463787}; Flags: Fragment;+++[J9JID5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 236 {ECO:0000313|Ensembl:ENSP00000322361};"]
[780,"'DDR1'",5573,6330,6697,6200,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005518///collagen binding+++GO:0038062///protein tyrosine kinase collagen receptor activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding","GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0006468///protein phosphorylation+++GO:0043583///ear development+++GO:0030154///cell differentiation+++GO:0007155///cell adhesion+++GO:0044319///wound healing, spreading of cells+++GO:0043066///negative regulation of apoptotic process+++GO:0001558///regulation of cell growth+++GO:0007595///lactation+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0009968///negative regulation of signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0007565///female pregnancy+++GO:1990138///neuron projection extension+++GO:0001952///regulation of cell-matrix adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0061564///axon development+++GO:0046777///protein autophosphorylation+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060749///mammary gland alveolus development+++GO:0030198///extracellular matrix organization+++GO:0014909///smooth muscle cell migration+++GO:0007566///embryo implantation+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0061302///smooth muscle cell-matrix adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway","discoidin domain receptor tyrosine kinase 1","[DDR1_HUMAN|Reviewed]RecName: Full=Epithelial discoidin domain-containing receptor 1; Short=Epithelial discoidin domain receptor 1; EC=2.7.10.1; AltName: Full=CD167 antigen-like family member A; AltName: Full=Cell adhesion kinase; AltName: Full=Discoidin receptor tyrosine kinase; AltName: Full=HGK2; AltName: Full=Mammary carcinoma kinase 10; Short=MCK-10; AltName: Full=Protein-tyrosine kinase 3A; AltName: Full=Protein-tyrosine kinase RTK-6; AltName: Full=TRK E; AltName: Full=Tyrosine kinase DDR; AltName: Full=Tyrosine-protein kinase CAK; AltName: CD_antigen=CD167a; Flags: Precursor;+++[A0A024RCJ0_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor family, member 1, isoform CRA_b {ECO:0000313|EMBL:EAX03343.1};+++[A0A024RCL1_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor family, member 1, isoform CRA_a {ECO:0000313|EMBL:EAX03342.1};+++[A0A024RCQ1_HUMAN|Unreviewed]SubName: Full=DDR1 {ECO:0000313|EMBL:AQY76774.1}; SubName: Full=Discoidin domain receptor family, member 1, isoform CRA_d {ECO:0000313|EMBL:EAX03341.1};+++[A0A0A0MSX3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000405998};+++[A0A0G2JHK4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000390043}; Flags: Fragment;+++[A0A0G2JI85_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000396139}; Flags: Fragment;+++[A0A0G2JIA2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000396609}; Flags: Fragment;+++[A0A0G2JIZ7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000403454}; Flags: Fragment;+++[A0A0G2JJA0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000406200}; Flags: Fragment;+++[A0A0G2JNZ7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000482421};+++[A0A140T972_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000394161}; Flags: Fragment;+++[A0A140T9T5_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000412396}; Flags: Fragment;+++[A2ABL0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000379631}; Flags: Fragment;+++[A2ABL2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000409682}; Flags: Fragment;+++[A2ABM8_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000398682}; Flags: Fragment;+++[D6R9C4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000422974}; Flags: Fragment;+++[D6RAJ3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421753};+++[D6RB35_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424468}; Flags: Fragment;+++[D6RB82_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424346}; Flags: Fragment;+++[D6RBU7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000392413}; Flags: Fragment;+++[D6RGW5_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421152}; Flags: Fragment;+++[E7EN94_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000420833}; Flags: Fragment;+++[E7ENJ2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000423492}; Flags: Fragment;+++[E7EPH4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000426420}; Flags: Fragment;+++[E7EPN2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000426229}; Flags: Fragment;+++[E7EQ23_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000425713}; Flags: Fragment;+++[E7EQ30_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000390593}; Flags: Fragment;+++[E7ERI6_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000394273}; Flags: Fragment;+++[E7ERN0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000422467}; Flags: Fragment;+++[E7ES06_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000422331}; Flags: Fragment;+++[E7ESR9_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000425113}; Flags: Fragment;+++[E7ETI3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000427597}; Flags: Fragment;+++[E7ETX3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000423906}; Flags: Fragment;+++[E7EUD5_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000427369}; Flags: Fragment;+++[E7EUP7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000423749}; Flags: Fragment;+++[E7EVT1_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421719}; Flags: Fragment;+++[E7EVW6_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421189}; Flags: Fragment;+++[E7EX99_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424758}; Flags: Fragment;+++[E7EXB0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424703}; Flags: Fragment;+++[H0Y717_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000409400}; Flags: Fragment;+++[H0Y9F4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424003}; Flags: Fragment;+++[H0YAH6_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000427124}; Flags: Fragment;+++[Q96T61_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor DDR1e {ECO:0000313|EMBL:AAK48843.1}; Flags: Fragment;+++[Q96T62_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor DDR1d {ECO:0000313|EMBL:AAK48842.1}; Flags: Fragment;"]
[785,"'CACNB4'",25,28,30,27.6666666666667,"05414///Dilated cardiomyopathy (DCM)+++04921///Oxytocin signaling pathway+++05410///Hypertrophic cardiomyopathy (HCM)+++04010///MAPK signaling pathway+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes","H00749///Episodic ataxias+++H00808///Idiopathic generalized epilepsies (IGEs)",null,null,"GO:0005829///cytosol+++GO:0005891///voltage-gated calcium channel complex+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0045202///synapse+++GO:0005886///plasma membrane","GO:0008331///high voltage-gated calcium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity+++GO:0005262///calcium channel activity+++GO:0005515///protein binding","GO:0070588///calcium ion transmembrane transport+++GO:1901385///regulation of voltage-gated calcium channel activity+++GO:0006811///ion transport+++GO:0007268///chemical synaptic transmission+++GO:0007528///neuromuscular junction development+++GO:0034765///regulation of ion transmembrane transport+++GO:0051899///membrane depolarization+++GO:0006816///calcium ion transport","calcium voltage-gated channel auxiliary subunit beta 4","[CACB4_HUMAN|Reviewed]RecName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000305}; Short=CAB4 {ECO:0000305}; AltName: Full=Calcium channel voltage-dependent subunit beta 4 {ECO:0000305};+++[A0A1B0GTA9_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489621};+++[A0A1B0GTF6_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489679};+++[A0A1B0GTH0_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490572};+++[A0A1B0GTK1_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489732};+++[A0A1B0GTL1_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489746};+++[A0A1B0GTN2_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489772}; Flags: Fragment;+++[A0A1B0GTN8_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489779};+++[A0A1B0GTP5_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489787};+++[A0A1B0GTP6_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489788};+++[A0A1B0GTS4_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489818};+++[A0A1B0GTX2_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489876};+++[A0A1B0GTX6_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489881};+++[A0A1B0GTX8_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489883};+++[A0A1B0GU05_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489912};+++[A0A1B0GU07_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489915}; Flags: Fragment;+++[A0A1B0GU32_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489943};+++[A0A1B0GU42_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489953};+++[A0A1B0GU53_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000489967};+++[A0A1B0GUI5_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490124};+++[A0A1B0GUI8_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490127};+++[A0A1B0GUJ7_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490138};+++[A0A1B0GUK3_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490144};+++[A0A1B0GUK4_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490145};+++[A0A1B0GUM9_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490176};+++[A0A1B0GUU5_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490249}; Flags: Fragment;+++[A0A1B0GUU8_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490252};+++[A0A1B0GUW8_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490430};+++[A0A1B0GV16_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490337};+++[A0A1B0GVB2_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490443};+++[A0A1B0GVF0_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490488};+++[A0A1B0GVG1_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490501};+++[A0A1B0GVP7_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490603}; Flags: Fragment;+++[A0A1B0GVT6_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490651};+++[A0A1B0GVU5_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490660};+++[A0A1B0GW58_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490787}; Flags: Fragment;+++[A0A1B0GW63_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490795};+++[A0A1B0GW81_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490817};+++[A0A1B0GWF9_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490910}; Flags: Fragment;+++[A0A1B0GWG5_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490918};+++[A0A1B0GXG0_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000353425};+++[A0A1C7CYX2_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000410978};+++[C9J224_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000399242}; Flags: Fragment;+++[E7DBM8_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000490510}; SubName: Full=Voltage-dependent calcium channel beta-4c subunit variant {ECO:0000313|EMBL:ADP09414.1};+++[E7EN11_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000380490};+++[H0Y476_HUMAN|Unreviewed]SubName: Full=Voltage-dependent L-type calcium channel subunit beta-4 {ECO:0000313|Ensembl:ENSP00000390161};+++[Q53S65_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CACNB4 {ECO:0000313|EMBL:AAY14759.1}; Flags: Fragment;+++[Q580I4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein CACNB4 {ECO:0000313|EMBL:AAX82014.1}; Flags: Fragment;+++[Q9NZA2_HUMAN|Unreviewed]SubName: Full=Voltage dependent calcium channel beta 4 subunit {ECO:0000313|EMBL:AAF61674.1}; Flags: Fragment;"]
[78986,"'DUSP26'",54,57,62,57.6666666666667,null,"H01994///Lafora disease+++H01601///Anaplastic large-cell lymphoma+++H01892///Peripheral T cell lymphoma (PTCL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus","GO:0004725///protein tyrosine phosphatase activity+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0002039///p53 binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0004647///phosphoserine phosphatase activity","GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0006470///protein dephosphorylation+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1902310///positive regulation of peptidyl-serine dephosphorylation+++GO:0045785///positive regulation of cell adhesion","dual specificity phosphatase 26","[DUS26_HUMAN|Reviewed]RecName: Full=Dual specificity protein phosphatase 26; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase SKRP3; AltName: Full=Low-molecular-mass dual-specificity phosphatase 4; Short=DSP-4; Short=LDP-4; AltName: Full=Mitogen-activated protein kinase phosphatase 8; Short=MAP kinase phosphatase 8; Short=MKP-8; AltName: Full=Novel amplified gene in thyroid anaplastic cancer;"]
[78999,"'LRFN4'",787,833,881,833.666666666667,"00720///Carbon fixation pathways in prokaryotes+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++00020///Citrate cycle (TCA cycle)+++01230///Biosynthesis of amino acids","H00073///Pyruvate carboxylase deficiency+++H01400///Secondary hyperammonemia","M00173///Reductive citrate cycle (Arnon-Buchanan cycle)","R00344///Pyruvate:carbon-dioxide ligase (ADP-forming) ATP + Pyruvate + HCO3- <=> ADP + Orthophosphate + Oxaloacetate","GO:0016020///membrane+++GO:0009986///cell surface+++GO:0098982///GABA-ergic synapse+++GO:0016021///integral component of membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding","GO:0099151///regulation of postsynaptic density assembly+++GO:1905606///regulation of presynapse assembly+++GO:0099560///synaptic membrane adhesion","leucine rich repeat and fibronectin type III domain containing 4","[LRFN4_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 4; Flags: Precursor;+++[A0A024R5I6_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat and fibronectin type III domain containing 4, isoform CRA_a {ECO:0000313|EMBL:EAW74574.1};+++[E7ENX6_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat and fibronectin type-III domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000377524};+++[Q6IPL6_HUMAN|Unreviewed]SubName: Full=LRFN4 protein {ECO:0000313|EMBL:AAH71866.1}; Flags: Fragment;+++[Q6PK41_HUMAN|Unreviewed]SubName: Full=LRFN4 protein {ECO:0000313|EMBL:AAH07718.1}; Flags: Fragment;+++[Q7L3C2_HUMAN|Unreviewed]SubName: Full=LRFN4 protein {ECO:0000313|EMBL:AAH14040.2}; Flags: Fragment;"]
[79027,"'ZNF655'",806,616.05,612.71,678.253333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 655","[ZN655_HUMAN|Reviewed]RecName: Full=Zinc finger protein 655; AltName: Full=Vav-interacting Krueppel-like protein;+++[C9IYG2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000392244}; Flags: Fragment;+++[C9J0V9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000392980};+++[C9J9R2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000398872}; Flags: Fragment;+++[C9JNK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000414969};+++[C9JS03_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000389260}; Flags: Fragment;+++[C9JUB9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000393750}; Flags: Fragment;+++[D6W5T3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655, isoform CRA_a {ECO:0000313|EMBL:EAW76649.1};+++[F8WCS2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000390295};+++[F8WDU5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000395799};+++[F8WE52_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000414007};+++[F8WEB1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 655 {ECO:0000313|Ensembl:ENSP00000408555};+++[Q68DU4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46177 fis, clone TESTI4003796, highly similar to Zinc finger protein 655 {ECO:0000313|EMBL:BAG54623.1};"]
[79039,"'DDX54'",1624,1710,1618,1650.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus","GO:0004004///ATP-dependent RNA helicase activity+++GO:0005102///signaling receptor binding+++GO:0003676///nucleic acid binding+++GO:0003714///transcription corepressor activity+++GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0030331///estrogen receptor binding+++GO:0003723///RNA binding+++GO:0016787///hydrolase activity+++GO:0005524///ATP binding","GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0016070///RNA metabolic process+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0006396///RNA processing","DEAD-box helicase 54","[DDX54_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX54; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase DP97; AltName: Full=DEAD box RNA helicase 97 kDa; AltName: Full=DEAD box protein 54;+++[F8VRX4_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX54 {ECO:0000313|Ensembl:ENSP00000448477}; Flags: Fragment;+++[H0YHH7_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX54 {ECO:0000313|Ensembl:ENSP00000447098}; Flags: Fragment;+++[H0YHZ9_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX54 {ECO:0000313|Ensembl:ENSP00000448189}; Flags: Fragment;"]
[79053,"'ALG8'",570,499,645,571.333333333333,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis","H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R06263///dolichyl beta-D-glucosyl phosphate:D-Glc-alpha-(1->3)-D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase   Dolichyl D-glucosyl phosphate + G10598 <=> Dolichyl phosphate + G10599","GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0004583///dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity+++GO:0005515///protein binding+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0042283///dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity+++GO:0042281///dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity","GO:0006486///protein glycosylation+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0097502///mannosylation","ALG8, alpha-1,3-glucosyltransferase","[ALG8_HUMAN|Reviewed]RecName: Full=Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase {ECO:0000250|UniProtKB:P40351}; EC=2.4.1.265 {ECO:0000250|UniProtKB:P40351}; AltName: Full=Asparagine-linked glycosylation protein 8 homolog; AltName: Full=Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase {ECO:0000250|UniProtKB:P40351}; AltName: Full=Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase {ECO:0000250|UniProtKB:P40351};+++[A0A024R5K5_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110};+++[A0A0S2Z5N3_HUMAN|Unreviewed]SubName: Full=Asparagine-linked glycosylation 8 alpha-13-glucosyltransferase-like protein isoform 2 {ECO:0000313|EMBL:ALQ34223.1};+++[E9PK79_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[E9PKA5_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[E9PLP7_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[E9PNE2_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110};+++[E9PP04_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[E9PP80_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110};+++[E9PP96_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[E9PR58_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[H0YCV0_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[H0YD42_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[H0YDD3_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[H0YDQ1_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[H0YDV4_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[H0YEE0_HUMAN|Unreviewed]RecName: Full=Alpha-1,3-glucosyltransferase {ECO:0000256|RuleBase:RU363110}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363110}; Flags: Fragment;+++[L8E8S9_HUMAN|Unreviewed]SubName: Full=Alternative protein ALG8 {ECO:0000313|EMBL:CCQ43710.1};"]
[79090,"'TRAPPC6A'",51,54,59,54.6666666666667,{"$nulls":4},"GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043087///regulation of GTPase activity+++GO:0048193///Golgi vesicle transport+++GO:1903232///melanosome assembly+++GO:0048208///COPII vesicle coating+++GO:0043473///pigmentation+++GO:0016192///vesicle-mediated transport","trafficking protein particle complex 6A","[TPC6A_HUMAN|Reviewed]RecName: Full=Trafficking protein particle complex subunit 6A {ECO:0000303|PubMed:19416478}; Short=TRAPP complex subunit 6A;+++[B7TZ90_HUMAN|Unreviewed]SubName: Full=TRAPPC6Adelta29-42 {ECO:0000313|EMBL:ACJ50530.1}; SubName: Full=Trafficking protein particle complex 6A, isoform CRA_a {ECO:0000313|EMBL:EAW57326.1};"]
[79102,"'RNF26'",1487,1575,1579,1547,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:1905719///protein localization to perinuclear region of cytoplasm+++GO:0070979///protein K11-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0050687///negative regulation of defense response to virus+++GO:0032479///regulation of type I interferon production+++GO:0007032///endosome organization","ring finger protein 26","[RNF26_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF26 {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:25254379, ECO:0000269|PubMed:27368102}; AltName: Full=RING finger protein 26 {ECO:0000305};"]
[79157,"'MFSD11'",193,188,171,184,"05168///Herpes simplex infection+++04137///Mitophagy - animal+++03040///Spliceosome+++04140///Autophagy - animal","H01481///Myelodysplastic syndrome (MDS)",null,null,"GO:0005575///cellular_component+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process","major facilitator superfamily domain containing 11","[MFS11_HUMAN|Reviewed]RecName: Full=UNC93-like protein MFSD11; AltName: Full=Major facilitator superfamily domain-containing protein 11; AltName: Full=Protein ET;+++[A0A024R8M6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW89453.1};+++[A0A024R8U7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW89450.1};+++[K7ELU3_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000466223}; Flags: Fragment;+++[K7EM95_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000466412};+++[K7EMP0_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000466584}; Flags: Fragment;+++[K7EQL2_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000467879};+++[K7ERE5_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000468223};+++[K7ES57_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000468562}; Flags: Fragment;+++[K7ES99_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000468616}; Flags: Fragment;+++[K7ESK9_HUMAN|Unreviewed]SubName: Full=UNC93-like protein MFSD11 {ECO:0000313|Ensembl:ENSP00000468758}; Flags: Fragment;"]
[79173,"'C19orf57'",29,15,31,25,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00768///Nonsyndromic autosomal recessive mental retardation (NS-ARMR)",null,null,"GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0007275///multicellular organism development","chromosome 19 open reading frame 57","[CS057_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf57; AltName: Full=Pre-T/NK cell-associated protein 3B3;+++[K7EIN8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000464829}; Flags: Fragment;+++[K7ELK3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000466119}; Flags: Fragment;+++[K7EMZ7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000466723};+++[K7EP60_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000467241}; Flags: Fragment;+++[K7ERY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf57 {ECO:0000313|Ensembl:ENSP00000468467}; Flags: Fragment;+++[L8EC49_HUMAN|Unreviewed]SubName: Full=Alternative protein C19orf57 {ECO:0000313|EMBL:CCQ42947.1};"]
[793,"'CALB1'",0,2,2,1.33333333333333,"04961///Endocrine and other factor-regulated calcium reabsorption",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0044305///calyx of Held+++GO:0044297///cell body+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0005737///cytoplasm+++GO:0099524///postsynaptic cytosol+++GO:0099523///presynaptic cytosol+++GO:0005634///nucleus+++GO:0043025///neuronal cell body+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0045202///synapse+++GO:0030425///dendrite+++GO:0098794///postsynapse+++GO:0070062///extracellular exosome+++GO:0030424///axon+++GO:0043005///neuron projection+++GO:0098982///GABA-ergic synapse","GO:0005515///protein binding+++GO:0005499///vitamin D binding+++GO:0099534///calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0099567///calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration+++GO:0005509///calcium ion binding","GO:0044267///cellular protein metabolic process+++GO:0007611///learning or memory+++GO:0007616///long-term memory+++GO:0071310///cellular response to organic substance+++GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:0007614///short-term memory+++GO:0072205///metanephric collecting duct development+++GO:0099509///regulation of presynaptic cytosolic calcium ion concentration+++GO:0048167///regulation of synaptic plasticity+++GO:0060041///retina development in camera-type eye+++GO:1900271///regulation of long-term synaptic potentiation+++GO:0007626///locomotory behavior+++GO:0010842///retina layer formation+++GO:0055074///calcium ion homeostasis+++GO:0035502///metanephric part of ureteric bud development+++GO:0072286///metanephric connecting tubule development+++GO:0072221///metanephric distal convoluted tubule development+++GO:0051480///regulation of cytosolic calcium ion concentration","calbindin 1","[CALB1_HUMAN|Reviewed]RecName: Full=Calbindin; AltName: Full=Calbindin D28; AltName: Full=D-28K; AltName: Full=Vitamin D-dependent calcium-binding protein, avian-type;+++[E5RG14_HUMAN|Unreviewed]SubName: Full=Calbindin {ECO:0000313|Ensembl:ENSP00000430281}; Flags: Fragment;+++[E5RIZ8_HUMAN|Unreviewed]SubName: Full=Calbindin {ECO:0000313|Ensembl:ENSP00000429246}; Flags: Fragment;+++[O75552_HUMAN|Unreviewed]SubName: Full=Vitamin D-dependent calcium binding protein calbindin {ECO:0000313|EMBL:AAC25277.1}; Flags: Fragment;"]
[79411,"'GLB1L'",545,508,572,541.666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005773///vacuole","GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0004565///beta-galactosidase activity+++GO:0016787///hydrolase activity","GO:0008152///metabolic process+++GO:0005975///carbohydrate metabolic process","galactosidase beta 1 like","[GLB1L_HUMAN|Reviewed]RecName: Full=Beta-galactosidase-1-like protein; EC=3.2.1.-; Flags: Precursor;+++[A0A024R439_HUMAN|Unreviewed]SubName: Full=Galactosidase, beta 1-like, isoform CRA_a {ECO:0000313|EMBL:EAW70712.1};+++[A0A140VJK0_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 74 {ECO:0000313|EMBL:AEE60987.1};+++[A0A1D5RMN7_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase-1-like protein {ECO:0000313|Ensembl:ENSP00000392018}; Flags: Fragment;+++[B4DTH1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55394, highly similar to Homo sapiens galactosidase, beta 1-like (GLB1L), mRNA {ECO:0000313|EMBL:BAG61983.1};+++[C9J1Y9_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase-1-like protein {ECO:0000313|Ensembl:ENSP00000400738}; Flags: Fragment;+++[C9JE41_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase-1-like protein {ECO:0000313|Ensembl:ENSP00000404698}; Flags: Fragment;+++[F8WCT5_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase-1-like protein {ECO:0000313|Ensembl:ENSP00000396263};+++[H7BZ46_HUMAN|Unreviewed]SubName: Full=Beta-galactosidase-1-like protein {ECO:0000313|Ensembl:ENSP00000387703}; Flags: Fragment;"]
[79576,"'NKAP'",199,205,188,197.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0031490///chromatin DNA binding+++GO:0005515///protein binding","GO:0019827///stem cell population maintenance+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0007219///Notch signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0071425///hematopoietic stem cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030851///granulocyte differentiation+++GO:0030097///hemopoiesis+++GO:0033077///T cell differentiation in thymus","NFKB activating protein","[NKAP_HUMAN|Reviewed]RecName: Full=NF-kappa-B-activating protein;+++[A0PJ73_HUMAN|Unreviewed]SubName: Full=NKAP protein {ECO:0000313|EMBL:AAH16783.1}; Flags: Fragment;+++[Q05D22_HUMAN|Unreviewed]SubName: Full=NKAP protein {ECO:0000313|EMBL:AAH18968.1}; Flags: Fragment;"]
[79595,"'SAP130'",1280,1172,1174,1208.66666666667,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0070062///extracellular exosome+++GO:0070822///Sin3-type complex+++GO:0005788///endoplasmic reticulum lumen+++GO:0016607///nuclear speck+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0044322///endoplasmic reticulum quality control compartment","GO:0003980///UDP-glucose:glycoprotein glucosyltransferase activity+++GO:0051082///unfolded protein binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:0051084///'de novo' posttranslational protein folding+++GO:0030968///endoplasmic reticulum unfolded protein response","Sin3A associated protein 130","[SP130_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP130; AltName: Full=130 kDa Sin3-associated polypeptide; AltName: Full=Sin3-associated polypeptide p130;+++[A0A2R8YDB8_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP130 {ECO:0000313|Ensembl:ENSP00000494423}; SubName: Full=Sin3A-associated protein, 130kDa, isoform CRA_d {ECO:0000313|EMBL:EAW95353.1};+++[C9J683_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP130 {ECO:0000313|Ensembl:ENSP00000411634}; Flags: Fragment;+++[C9JTJ5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP130 {ECO:0000313|Ensembl:ENSP00000414593}; Flags: Fragment;+++[H7BXF5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP130 {ECO:0000313|Ensembl:ENSP00000259234};+++[Q96DP1_HUMAN|Unreviewed]SubName: Full=Sin3A-associated protein, 130kDa, isoform CRA_c {ECO:0000313|EMBL:EAW95352.1}; SubName: Full=cDNA FLJ31417 fis, clone NT2NE2000327, weakly similar to GLUCOAMYLASE S1/S2 {ECO:0000313|EMBL:BAB71063.1}; Flags: Fragment;"]
[79627,"'OGFRL1'",1588.9,2122.11,1458.11,1723.04,{"$nulls":4},"GO:0016020///membrane","GO:0004985///opioid receptor activity+++GO:0038023///signaling receptor activity","GO:0038003///opioid receptor signaling pathway","opioid growth factor receptor like 1","[OGRL1_HUMAN|Reviewed]RecName: Full=Opioid growth factor receptor-like protein 1;"]
[79642,"'ARSJ'",114,84,65,87.6666666666667,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0016020///membrane","GO:0008484///sulfuric ester hydrolase activity+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0004065///arylsulfatase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0008152///metabolic process","arylsulfatase family member J","[ARSJ_HUMAN|Reviewed]RecName: Full=Arylsulfatase J; Short=ASJ; EC=3.1.6.-; Flags: Precursor;+++[D6RGC1_HUMAN|Unreviewed]SubName: Full=Arylsulfatase J {ECO:0000313|Ensembl:ENSP00000421327};+++[Q8N5N6_HUMAN|Unreviewed]SubName: Full=ARSJ protein {ECO:0000313|EMBL:AAH32010.1};"]
[79663,"'HSPBAP1'",41,60,73,58,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding",null,"HSPB1 associated protein 1","[HBAP1_HUMAN|Reviewed]RecName: Full=HSPB1-associated protein 1; AltName: Full=27 kDa heat shock protein-associated protein 1; AltName: Full=Protein associated with small stress protein 1;+++[A8K045_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76988, highly similar to Homo sapiens HSPB (heat shock 27kDa) associated protein 1 (HSPBAP1), mRNA {ECO:0000313|EMBL:BAF82099.1};"]
[79682,"'CENPU'",21,29,22,24,null,"H02041///Myopia",null,null,"GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0000775///chromosome, centromeric region+++GO:0005815///microtubule organizing center+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore+++GO:0000776///kinetochore+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0043009///chordate embryonic development+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0016032///viral process","centromere protein U","[CENPU_HUMAN|Reviewed]RecName: Full=Centromere protein U; Short=CENP-U; AltName: Full=Centromere protein of 50 kDa; Short=CENP-50; AltName: Full=Interphase centromere complex protein 24; AltName: Full=KSHV latent nuclear antigen-interacting protein 1; AltName: Full=MLF1-interacting protein; AltName: Full=Polo-box-interacting protein 1;+++[A5D8X7_HUMAN|Unreviewed]SubName: Full=MLF1IP protein {ECO:0000313|EMBL:AAI41855.1};+++[D6R9S4_HUMAN|Unreviewed]SubName: Full=Centromere protein U {ECO:0000313|Ensembl:ENSP00000423167}; Flags: Fragment;+++[Q09GN1_HUMAN|Unreviewed]SubName: Full=Centromere protein U {ECO:0000313|Ensembl:ENSP00000423248}; SubName: Full=MLF1 interacting protein isoform 2 {ECO:0000313|EMBL:ABI49143.1};"]
[79703,"'C11orf80'",347,393,370,370,"04137///Mitophagy - animal+++00900///Terpenoid backbone biosynthesis+++01130///Biosynthesis of antibiotics+++04140///Autophagy - animal","H00230///Hereditary spherocytosis (SPH)+++H01891///Autosomal recessive spinocerebellar ataxias+++H00231///Hereditary elliptocytosis (HE)+++H00063///Spinocerebellar ataxia (SCA)",null,"R09845///CAAX protease S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005694///chromosome","GO:0004222///metalloendopeptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003779///actin binding+++GO:0098918///structural constituent of synapse+++GO:0005200///structural constituent of cytoskeleton+++GO:0004175///endopeptidase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0005543///phospholipid binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity","GO:0007131///reciprocal meiotic recombination+++GO:0051321///meiotic cell cycle+++GO:0042138///meiotic DNA double-strand break formation","chromosome 11 open reading frame 80","[TO6BL_HUMAN|Reviewed]RecName: Full=Type 2 DNA topoisomerase 6 subunit B-like {ECO:0000250|UniProtKB:J3QMY9}; AltName: Full=Type 2 DNA topoisomerase VI subunit B-like {ECO:0000250|UniProtKB:J3QMY9}; Short=TOPOVIBL {ECO:0000250|UniProtKB:J3QMY9};+++[A0A0A0MRH1_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000354227};+++[A0A140TA08_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000434648};+++[A0A2R8Y5A2_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000494645};+++[A0A2U3TZP7_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000432039};+++[B4DXL1_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000444319}; SubName: Full=cDNA FLJ55941 {ECO:0000313|EMBL:BAG63423.1};+++[E9PJS1_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000435512};+++[E9PKM2_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000431578};+++[E9PMI8_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000434960}; Flags: Fragment;+++[E9PMU2_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000437319}; Flags: Fragment;+++[E9PNG9_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000437143};+++[H0YD22_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000432775}; Flags: Fragment;+++[H0YD55_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000433032}; Flags: Fragment;+++[H0YDL3_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000433869}; Flags: Fragment;+++[H0YE21_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 80 {ECO:0000313|Ensembl:ENSP00000434804};"]
[79724,"'ZNF768'",1175,1291,1221,1229,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005665///RNA polymerase II, core complex+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006366///transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 768","[ZN768_HUMAN|Reviewed]RecName: Full=Zinc finger protein 768;+++[A0A024QZC8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW52242.1};+++[H3BS42_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 768 {ECO:0000313|Ensembl:ENSP00000456527};"]
[79725,"'THAP9'",26,26,31,27.6666666666667,"04141///Protein processing in endoplasmic reticulum+++04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00404///COPII complex",null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0070971///endoplasmic reticulum exit site+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm+++GO:0030120///vesicle coat+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030127///COPII vesicle coat+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0004803///transposase activity+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0016740///transferase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006313///transposition, DNA-mediated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006310///DNA recombination+++GO:0015074///DNA integration","THAP domain containing 9","[THAP9_HUMAN|Reviewed]RecName: Full=DNA transposase THAP9; EC=2.7.7.-; AltName: Full=THAP domain-containing protein 9; Short=hTh9;+++[D6R957_HUMAN|Unreviewed]SubName: Full=DNA transposase THAP9 {ECO:0000313|Ensembl:ENSP00000423622};+++[D6RCT5_HUMAN|Unreviewed]SubName: Full=DNA transposase THAP9 {ECO:0000313|Ensembl:ENSP00000425503};+++[D6REM3_HUMAN|Unreviewed]SubName: Full=DNA transposase THAP9 {ECO:0000313|Ensembl:ENSP00000426750};+++[F2Z371_HUMAN|Unreviewed]SubName: Full=DNA transposase THAP9 {ECO:0000313|Ensembl:ENSP00000425966};+++[H0Y9F3_HUMAN|Unreviewed]SubName: Full=DNA transposase THAP9 {ECO:0000313|Ensembl:ENSP00000424001}; Flags: Fragment;"]
[79744,"'ZNF419'",83.14,95.72,86,88.2866666666667,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 419","[ZN419_HUMAN|Reviewed]RecName: Full=Zinc finger protein 419;+++[A6NNZ3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000346136};+++[E5RGL3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000427723};+++[E5RH62_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000429880}; Flags: Fragment;+++[E5RHS2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000428523}; Flags: Fragment;+++[E5RHW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000429628}; Flags: Fragment;+++[E5RHZ9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000428515}; Flags: Fragment;+++[E5RI89_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000429504}; Flags: Fragment;+++[E5RIA3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000429471};+++[E5RJT6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 419 {ECO:0000313|Ensembl:ENSP00000428181}; Flags: Fragment;"]
[79763,"'ISOC2'",1640,1608,2014,1754,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003824///catalytic activity","GO:0031648///protein destabilization","isochorismatase domain containing 2","[ISOC2_HUMAN|Reviewed]RecName: Full=Isochorismatase domain-containing protein 2;+++[K7EKW4_HUMAN|Unreviewed]SubName: Full=Isochorismatase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000465814}; Flags: Fragment;+++[K7ENV7_HUMAN|Unreviewed]SubName: Full=Isochorismatase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000467111}; Flags: Fragment;"]
[7979,"'SEM1'",148,173,233,184.666666666667,"03050///Proteasome+++03440///Homologous recombination+++05169///Epstein-Barr virus infection",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0000502///proteasome complex+++GO:0005654///nucleoplasm+++GO:0008541///proteasome regulatory particle, lid subcomplex","GO:0003713///transcription coactivator activity+++GO:0035035///histone acetyltransferase binding+++GO:0005515///protein binding","GO:0006397///mRNA processing+++GO:0016579///protein deubiquitination+++GO:0006406///mRNA export from nucleus+++GO:0000724///double-strand break repair via homologous recombination+++GO:0043687///post-translational protein modification+++GO:0008380///RNA splicing+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0006110///regulation of glycolytic process+++GO:0043248///proteasome assembly+++GO:0006366///transcription by RNA polymerase II+++GO:0008283///cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II","SEM1, 26S proteasome complex subunit","[SEM1_HUMAN|Reviewed]RecName: Full=26S proteasome complex subunit SEM1; AltName: Full=26S proteasome complex subunit DSS1; AltName: Full=Deleted in split hand/split foot protein 1; AltName: Full=Split hand/foot deleted protein 1; AltName: Full=Split hand/foot malformation type 1 protein;+++[SEML_HUMAN|Reviewed]RecName: Full=Putative protein SEM1, isoform 2 {ECO:0000244|HGNC:HGNC:10845};+++[A0A087WUG5_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000478651};+++[A0A087WXB9_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000480885};+++[A0A087WYU0_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000482085};+++[A0A087X1V0_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000484478};+++[A0A087X261_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000484726};+++[A0A096LP17_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000485341}; SubName: Full=Split hand/foot malformation (Ectrodactyly) type 1, isoform CRA_b {ECO:0000313|EMBL:EAW76747.1};+++[A0A096LP28_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000485353};+++[B7ZVW6_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000481021}; SubName: Full=FLJ42280 protein {ECO:0000313|EMBL:AAI71740.1};+++[F2Z2L7_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000390049};+++[F2Z2N6_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000416322};+++[F2Z309_HUMAN|Unreviewed]SubName: Full=26S proteasome complex subunit SEM1 {ECO:0000313|Ensembl:ENSP00000409481};+++[Q6IBB7_HUMAN|Unreviewed]SubName: Full=SHFM1 protein {ECO:0000313|EMBL:CAG33168.1}; SubName: Full=Split hand/foot malformation (Ectrodactyly) type 1 {ECO:0000313|EMBL:EAL24125.1}; SubName: Full=Split hand/foot malformation (Ectrodactyly) type 1, isoform CRA_a {ECO:0000313|EMBL:EAW76746.1}; SubName: Full=cDNA FLJ76393, highly similar to Homo sapiens split hand/foot malformation (ectrodactyly) type 1 (SHFM1), mRNA {ECO:0000313|EMBL:BAF83759.1};"]
[79812,"'MMRN2'",8,3,7,6,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0005201///extracellular matrix structural constituent+++GO:0030023///extracellular matrix constituent conferring elasticity","GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0001525///angiogenesis+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0002042///cell migration involved in sprouting angiogenesis","multimerin 2","[MMRN2_HUMAN|Reviewed]RecName: Full=Multimerin-2; AltName: Full=EMILIN-3; AltName: Full=Elastin microfibril interface located protein 3; Short=Elastin microfibril interfacer 3; AltName: Full=EndoGlyx-1 p125/p140 subunit; Flags: Precursor;+++[L8E8T6_HUMAN|Unreviewed]SubName: Full=Alternative protein MMRN2 {ECO:0000313|EMBL:CCQ43720.1};+++[R4GMY6_HUMAN|Unreviewed]SubName: Full=Multimerin-2 {ECO:0000313|Ensembl:ENSP00000473405}; Flags: Fragment;+++[V9GY37_HUMAN|Unreviewed]SubName: Full=Multimerin-2 {ECO:0000313|Ensembl:ENSP00000476355};+++[V9GY43_HUMAN|Unreviewed]SubName: Full=Multimerin-2 {ECO:0000313|Ensembl:ENSP00000476378}; Flags: Fragment;+++[V9GYS9_HUMAN|Unreviewed]SubName: Full=Multimerin-2 {ECO:0000313|Ensembl:ENSP00000477052}; Flags: Fragment;"]
[79828,"'METTL8'",127,126.09,100,117.696666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0008174///mRNA methyltransferase activity+++GO:0016740///transferase activity+++GO:0004402///histone acetyltransferase activity+++GO:0052735///tRNA (cytosine-3-)-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0016573///histone acetylation+++GO:0045444///fat cell differentiation+++GO:0032259///methylation+++GO:0007519///skeletal muscle tissue development+++GO:0030488///tRNA methylation+++GO:0080009///mRNA methylation","methyltransferase like 8","[METL8_HUMAN|Reviewed]RecName: Full=Methyltransferase-like protein 8; EC=2.1.1.-;+++[A8K7U3_HUMAN|Unreviewed]RecName: Full=Methyltransferase-like protein {ECO:0000256|PIRNR:PIRNR037755}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};+++[B3KW44_HUMAN|Unreviewed]RecName: Full=Methyltransferase-like protein {ECO:0000256|PIRNR:PIRNR037755}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};+++[B4DLT0_HUMAN|Unreviewed]RecName: Full=Methyltransferase-like protein {ECO:0000256|PIRNR:PIRNR037755}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};+++[B5ME25_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 8 {ECO:0000313|Ensembl:ENSP00000376377}; Flags: Fragment;+++[C9J3F1_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 8 {ECO:0000313|Ensembl:ENSP00000411942}; Flags: Fragment;+++[C9J6U8_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 8 {ECO:0000313|Ensembl:ENSP00000411589}; Flags: Fragment;+++[C9JE69_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 8 {ECO:0000313|Ensembl:ENSP00000404646}; Flags: Fragment;+++[E7ETE0_HUMAN|Unreviewed]RecName: Full=Methyltransferase-like protein {ECO:0000256|PIRNR:PIRNR037755}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};+++[H7C2P8_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 8 {ECO:0000313|Ensembl:ENSP00000407180}; Flags: Fragment;"]
[79847,"'MFSD13A'",17,14.72,25,18.9066666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"major facilitator superfamily domain containing 13A","[MF13A_HUMAN|Reviewed]RecName: Full=Transmembrane protein 180 {ECO:0000312|HGNC:HGNC:26196}; AltName: Full=Major facilitator superfamily domain-containing 13A {ECO:0000312|HGNC:HGNC:26196};+++[A0A1B0GUX1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 180 {ECO:0000313|Ensembl:ENSP00000490281}; Flags: Fragment;+++[Q6UWF4_HUMAN|Unreviewed]SubName: Full=GLGQ5807 {ECO:0000313|EMBL:AAQ89168.1}; SubName: Full=Transmembrane protein 180 {ECO:0000313|Ensembl:ENSP00000358947};"]
[79868,"'ALG13'",415,366,348,376.333333333333,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis+++00513///Various types of N-glycan biosynthesis","H00118///Congenital disorders of glycosylation (CDG) type I+++H00606///Early infantile epileptic encephalopathy","M00055///N-glycan precursor biosynthesis","R05970///UDP-N-acetyl-D-glucosamine + N-Acetyl-D-glucosaminyldiphosphodolichol <=> UDP + N,N'-Chitobiosyldiphosphodolichol","GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0016758///transferase activity, transferring hexosyl groups+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0003723///RNA binding+++GO:0004577///N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity+++GO:0008233///peptidase activity","GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006508///proteolysis+++GO:0008152///metabolic process","ALG13, UDP-N-acetylglucosaminyltransferase subunit","[ALG13_HUMAN|Reviewed]RecName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13; EC=2.4.1.141; EC=3.4.19.12; AltName: Full=Asparagine-linked glycosylation 13 homolog; AltName: Full=Glycosyltransferase 28 domain-containing protein 1; AltName: Full=UDP-N-acetylglucosamine transferase subunit ALG13 homolog;+++[A0A087WT15_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000477513};+++[A0A087WTT9_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000478130};+++[A0A087WVG5_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000479424};+++[A0A087WX01_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000480638};+++[A0A087WX43_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000480711};+++[A0A096LNJ4_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485067};+++[A0A096LNJ5_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485071}; Flags: Fragment;+++[A0A096LNL2_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485093};+++[A0A096LP10_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485333}; Flags: Fragment;+++[A0A096LP54_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485400}; Flags: Fragment;+++[A0A096LPI3_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485624}; Flags: Fragment;+++[A0A096LPK3_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000485658}; Flags: Fragment;+++[A0A1B0GVW6_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000490681};+++[D6RE84_HUMAN|Unreviewed]SubName: Full=Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 {ECO:0000313|Ensembl:ENSP00000426892};"]
[79891,"'ZNF671'",109,70,116,98.3333333333333,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 671","[ZN671_HUMAN|Reviewed]RecName: Full=Zinc finger protein 671;+++[B7Z1N1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57718, highly similar to Zinc finger protein 671 {ECO:0000313|EMBL:BAH11567.1};+++[M0QX87_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 671 {ECO:0000313|Ensembl:ENSP00000468976};+++[M0R091_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 671 {ECO:0000313|Ensembl:ENSP00000471087};"]
[79903,"'NAA60'",1515,1751,1611,1625.66666666667,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0042803///protein homodimerization activity+++GO:0010485///H4 histone acetyltransferase activity+++GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004402///histone acetyltransferase activity","GO:0006474///N-terminal protein amino acid acetylation+++GO:0043966///histone H3 acetylation+++GO:0006325///chromatin organization+++GO:0043967///histone H4 acetylation+++GO:0007059///chromosome segregation+++GO:0006334///nucleosome assembly+++GO:0008283///cell proliferation+++GO:0017196///N-terminal peptidyl-methionine acetylation","N(alpha)-acetyltransferase 60, NatF catalytic subunit","[NAA60_HUMAN|Reviewed]RecName: Full=N-alpha-acetyltransferase 60 {ECO:0000303|PubMed:25732826, ECO:0000312|HGNC:HGNC:25875}; Short=hNaa60 {ECO:0000303|PubMed:27320834, ECO:0000303|PubMed:27550639}; EC=2.3.1.259 {ECO:0000269|PubMed:25732826}; AltName: Full=Histone acetyltransferase type B protein 4 {ECO:0000303|PubMed:21981917}; Short=HAT4 {ECO:0000303|PubMed:21981917}; EC=2.3.1.48 {ECO:0000305|PubMed:21981917}; AltName: Full=N-acetyltransferase 15; AltName: Full=N-alpha-acetyltransferase F; Short=NatF;+++[A0A087WZ48_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000482351};+++[I3L115_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000458505}; Flags: Fragment;+++[I3L153_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000458575};+++[I3L1B9_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000458717};+++[I3L1L7_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000458928}; Flags: Fragment;+++[I3L1T4_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000459084}; Flags: Fragment;+++[I3L1X5_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000459188}; Flags: Fragment;+++[I3L205_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000459275}; Flags: Fragment;+++[I3L2B4_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000459544}; Flags: Fragment;+++[I3L2K7_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000459750}; Flags: Fragment;+++[I3L2M6_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000459790}; Flags: Fragment;+++[I3L4Q3_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000461438};+++[I3L4Q5_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000461443}; Flags: Fragment;+++[I3L4T5_HUMAN|Unreviewed]SubName: Full=N-alpha-acetyltransferase 60 {ECO:0000313|Ensembl:ENSP00000461507}; Flags: Fragment;"]
[79939,"'SLC35E1'",2221,2102,2079,2134,{"$nulls":4},"GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane",null,null,"solute carrier family 35 member E1","[S35E1_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member E1;+++[A0A024R7G7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35, member E1, isoform CRA_c {ECO:0000313|EMBL:EAW84553.1};+++[A0A0A0MSG4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member E1 {ECO:0000313|Ensembl:ENSP00000387152}; Flags: Fragment;+++[C9JK45_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member E1 {ECO:0000313|Ensembl:ENSP00000394092}; Flags: Fragment;+++[H7C1I0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member E1 {ECO:0000313|Ensembl:ENSP00000400435}; Flags: Fragment;+++[Q9H7U6_HUMAN|Unreviewed]SubName: Full=SLC35E1 protein {ECO:0000313|EMBL:CAG33607.1}; SubName: Full=cDNA FLJ14251 fis, clone OVARC1001329 {ECO:0000313|EMBL:BAB14879.1};"]
[79956,"'ERMP1'",593,562,440,531.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0006508///proteolysis","endoplasmic reticulum metallopeptidase 1","[ERMP1_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum metallopeptidase 1 {ECO:0000250|UniProtKB:Q6UPR8, ECO:0000312|HGNC:HGNC:23703}; EC=3.4.-.- {ECO:0000305}; AltName: Full=Felix-ina {ECO:0000250|UniProtKB:Q6UPR8};+++[A0A0C4DGF0_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum metallopeptidase 1 {ECO:0000313|Ensembl:ENSP00000432986};+++[D3DRI3_HUMAN|Unreviewed]SubName: Full=KIAA1815, isoform CRA_a {ECO:0000313|EMBL:EAW58758.1};+++[E7ER77_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum metallopeptidase 1 {ECO:0000313|Ensembl:ENSP00000417474};+++[Q6ZMD3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ23992 fis, clone HRC08583 {ECO:0000313|EMBL:BAD18796.1};"]
[800,"'CALD1'",42756,46395,33337,40829.3333333333,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030016///myofibril+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0030478///actin cap","GO:0003779///actin binding+++GO:0017022///myosin binding+++GO:0005516///calmodulin binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0005523///tropomyosin binding","GO:0006936///muscle contraction","caldesmon 1","[CALD1_HUMAN|Reviewed]RecName: Full=Caldesmon; Short=CDM;+++[A0A140VKA0_HUMAN|Unreviewed]SubName: Full=Caldesmon 1, isoform CRA_i {ECO:0000313|EMBL:EAW83834.1}; SubName: Full=Testis secretory sperm-binding protein Li 227n {ECO:0000313|EMBL:AEE61237.1};+++[C9J813_HUMAN|Unreviewed]SubName: Full=Caldesmon {ECO:0000313|Ensembl:ENSP00000411476}; Flags: Fragment;+++[C9JE79_HUMAN|Unreviewed]SubName: Full=Caldesmon {ECO:0000313|Ensembl:ENSP00000416611}; Flags: Fragment;+++[C9JEK3_HUMAN|Unreviewed]SubName: Full=Caldesmon {ECO:0000313|Ensembl:ENSP00000390926}; Flags: Fragment;+++[E7EX44_HUMAN|Unreviewed]SubName: Full=Caldesmon {ECO:0000313|Ensembl:ENSP00000419673};+++[E9PGZ1_HUMAN|Unreviewed]SubName: Full=Caldesmon {ECO:0000313|Ensembl:ENSP00000407522};+++[F8WE61_HUMAN|Unreviewed]SubName: Full=Caldesmon {ECO:0000313|Ensembl:ENSP00000394715};+++[Q05DR4_HUMAN|Unreviewed]SubName: Full=CALD1 protein {ECO:0000313|EMBL:AAH05006.1}; Flags: Fragment;+++[Q6P707_HUMAN|Unreviewed]SubName: Full=CALD1 protein {ECO:0000313|EMBL:AAH61926.1}; Flags: Fragment;+++[Q6PJM5_HUMAN|Unreviewed]SubName: Full=CALD1 protein {ECO:0000313|EMBL:AAH14035.1}; Flags: Fragment;+++[Q9NYG1_HUMAN|Unreviewed]SubName: Full=Caldesmon 1, isoform CRA_b {ECO:0000313|EMBL:EAW83827.1}; SubName: Full=NAG22 protein {ECO:0000313|EMBL:AAF69498.3};"]
[8001,"'GLRA3'",0,1,0,0.333333333333333,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0043005///neuron projection+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0043204///perikaryon+++GO:0098794///postsynapse+++GO:0034707///chloride channel complex+++GO:0016935///glycine-gated chloride channel complex+++GO:0005887///integral component of plasma membrane+++GO:0045202///synapse+++GO:0030425///dendrite","GO:0005216///ion channel activity+++GO:0030594///neurotransmitter receptor activity+++GO:0016594///glycine binding+++GO:0046872///metal ion binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005254///chloride channel activity+++GO:0016934///extracellularly glycine-gated chloride channel activity+++GO:0022824///transmitter-gated ion channel activity+++GO:0022852///glycine-gated chloride ion channel activity+++GO:0005230///extracellular ligand-gated ion channel activity","GO:0007165///signal transduction+++GO:0007268///chemical synaptic transmission+++GO:0006821///chloride transport+++GO:0042391///regulation of membrane potential+++GO:0060079///excitatory postsynaptic potential+++GO:0050877///nervous system process+++GO:0043200///response to amino acid+++GO:0060012///synaptic transmission, glycinergic+++GO:0006811///ion transport+++GO:1902476///chloride transmembrane transport+++GO:0007218///neuropeptide signaling pathway+++GO:0034220///ion transmembrane transport+++GO:0051260///protein homooligomerization","glycine receptor alpha 3","[GLRA3_HUMAN|Reviewed]RecName: Full=Glycine receptor subunit alpha-3; Flags: Precursor;+++[Q4W595_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein GLRA3 {ECO:0000313|EMBL:AAY40916.1}; Flags: Fragment;+++[Q9UPF3_HUMAN|Unreviewed]SubName: Full=Glycine receptor alpha 3 subunit {ECO:0000313|EMBL:AAC39918.1}; Flags: Fragment;"]
[80063,"'ATF7IP2'",81,70,74,75,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003964///RNA-directed DNA polymerase activity","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","activating transcription factor 7 interacting protein 2","[MCAF2_HUMAN|Reviewed]RecName: Full=Activating transcription factor 7-interacting protein 2; Short=ATF7-interacting protein 2; AltName: Full=MBD1-containing chromatin-associated factor 2;+++[B4DKH3_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000446119}; SubName: Full=cDNA FLJ57516, highly similar to Homo sapiens activating transcription factor 7 interacting protein 2 (ATF7IP2), mRNA {ECO:0000313|EMBL:BAG59185.1};+++[F5GY73_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000440791};+++[H3BNE6_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000454809}; Flags: Fragment;+++[H3BPC9_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000455259};+++[H3BR07_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000456023}; Flags: Fragment;+++[H3BUP1_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000457731}; Flags: Fragment;+++[I3L4M8_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 7-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000461383}; Flags: Fragment;"]
[801,"'CALM1'",5463,4450,4931,4948,"04270///Vascular smooth muscle contraction+++05010///Alzheimer's disease+++04915///Estrogen signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04625///C-type lectin receptor signaling pathway+++04922///Glucagon signaling pathway+++05152///Tuberculosis+++04020///Calcium signaling pathway+++04970///Salivary secretion+++05163///Human cytomegalovirus infection+++05031///Amphetamine addiction+++04744///Phototransduction+++04016///MAPK signaling pathway - plant+++04070///Phosphatidylinositol signaling system+++04925///Aldosterone synthesis and secretion+++04015///Rap1 signaling pathway+++04740///Olfactory transduction+++05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04924///Renin secretion+++04720///Long-term potentiation+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04745///Phototransduction - fly+++04971///Gastric acid secretion+++04014///Ras signaling pathway+++04916///Melanogenesis+++05133///Pertussis+++05034///Alcoholism+++04371///Apelin signaling pathway+++04728///Dopaminergic synapse+++04626///Plant-pathogen interaction+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++05214///Glioma+++04022///cGMP-PKG signaling pathway+++04114///Oocyte meiosis+++04921///Oxytocin signaling pathway+++04024///cAMP signaling pathway+++04912///GnRH signaling pathway+++04910///Insulin signaling pathway+++04722///Neurotrophin signaling pathway+++04713///Circadian entrainment","H01019///Catecholaminergic polymorphic ventricular tachycardia+++H00720///Long QT syndrome",null,null,"GO:0043209///myelin sheath+++GO:0005819///spindle+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0031982///vesicle+++GO:0034704///calcium channel complex+++GO:1902494///catalytic complex+++GO:0030426///growth cone+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0005576///extracellular region+++GO:0005876///spindle microtubule+++GO:0031966///mitochondrial membrane+++GO:0030672///synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0008076///voltage-gated potassium channel complex+++GO:0030017///sarcomere+++GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0032991///protein-containing complex","GO:0047485///protein N-terminus binding+++GO:0008179///adenylate cyclase binding+++GO:0031800///type 3 metabotropic glutamate receptor binding+++GO:0019904///protein domain specific binding+++GO:0019855///calcium channel inhibitor activity+++GO:0048306///calcium-dependent protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0072542///protein phosphatase activator activity+++GO:0016301///kinase activity+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0010856///adenylate cyclase activator activity+++GO:0031432///titin binding+++GO:0031997///N-terminal myristoylation domain binding+++GO:0044325///ion channel binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0050998///nitric-oxide synthase binding+++GO:0019901///protein kinase binding+++GO:0097718///disordered domain specific binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0008440///inositol-1,4,5-trisphosphate 3-kinase activity","GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0001975///response to amphetamine+++GO:0005513///detection of calcium ion+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0055117///regulation of cardiac muscle contraction+++GO:0016310///phosphorylation+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0043647///inositol phosphate metabolic process+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0000165///MAPK cascade+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0019722///calcium-mediated signaling+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0007190///activation of adenylate cyclase activity+++GO:0075206///positive regulation by host of symbiont cAMP-mediated signal transduction+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:0021762///substantia nigra development+++GO:0051412///response to corticosterone+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0051186///cofactor metabolic process+++GO:0002027///regulation of heart rate+++GO:0006936///muscle contraction+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0051592///response to calcium ion+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0090150///establishment of protein localization to membrane+++GO:0002576///platelet degranulation+++GO:0090151///establishment of protein localization to mitochondrial membrane+++GO:0032465///regulation of cytokinesis+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0043388///positive regulation of DNA binding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:1900242///regulation of synaptic vesicle endocytosis","calmodulin 1","[CALM1_HUMAN|Reviewed]RecName: Full=Calmodulin-1 {ECO:0000312|HGNC:HGNC:1442};+++[CALM2_HUMAN|Reviewed]RecName: Full=Calmodulin-2 {ECO:0000312|HGNC:HGNC:1445};+++[CALM3_HUMAN|Reviewed]RecName: Full=Calmodulin-3 {ECO:0000312|HGNC:HGNC:1449};+++[B4DJ51_HUMAN|Unreviewed]SubName: Full=Calmodulin 1 (Phosphorylase kinase, delta), isoform CRA_a {ECO:0000313|EMBL:EAW81427.1}; SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_b {ECO:0000313|EMBL:EAW57426.1}; SubName: Full=Epididymis secretory protein Li 72 {ECO:0000313|EMBL:ACI46002.1}; SubName: Full=cDNA FLJ61744, highly similar to Calmodulin {ECO:0000313|EMBL:BAG58713.1};+++[E7ETZ0_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000403491};+++[G3V226_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000450425};+++[G3V361_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000451062}; Flags: Fragment;+++[G3V479_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000451646};+++[M0QZ52_HUMAN|Unreviewed]SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_d {ECO:0000313|EMBL:EAW57428.1}; SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000486402}; SubName: Full=Calmodulin-2 {ECO:0000313|Ensembl:ENSP00000486952}; SubName: Full=Calmodulin-3 {ECO:0000313|Ensembl:ENSP00000470308};"]
[80125,"'CCDC33'",8,2,6,5.33333333333333,{"$nulls":5},"GO:0005515///protein binding",null,"coiled-coil domain containing 33","[CCD33_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 33; AltName: Full=Cancer/testis antigen 61; Short=CT61;+++[A0A1B0GV97_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 33 {ECO:0000313|Ensembl:ENSP00000490425}; Flags: Fragment;+++[D3DW55_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 33, isoform CRA_c {ECO:0000313|EMBL:EAW99347.1};+++[F1T0M3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAJ84097.1};+++[H0YMB8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 33 {ECO:0000313|Ensembl:ENSP00000453542}; Flags: Fragment;"]
[80167,"'ABHD18'",73,72,59.73,68.2433333333333,"04137///Mitophagy - animal+++04142///Lysosome+++04140///Autophagy - animal","H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H00149///Neuronal ceroid lipofuscinosis (NCL)+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005576///extracellular region",null,"GO:0007040///lysosome organization+++GO:0055085///transmembrane transport+++GO:0048666///neuron development+++GO:0010506///regulation of autophagy","abhydrolase domain containing 18","[ABD18_HUMAN|Reviewed]RecName: Full=Protein ABHD18 {ECO:0000305}; AltName: Full=Alpha/beta hydrolase domain-containing protein 18 {ECO:0000305}; Short=Abhydrolase domain-containing protein 18 {ECO:0000312|HGNC:HGNC:26111}; Flags: Precursor;+++[A0A2R8YEZ0_HUMAN|Unreviewed]SubName: Full=Protein ABHD18 {ECO:0000313|Ensembl:ENSP00000496010};+++[B7WP89_HUMAN|Unreviewed]SubName: Full=Protein ABHD18 {ECO:0000313|Ensembl:ENSP00000373447};+++[D6RD85_HUMAN|Unreviewed]SubName: Full=Protein ABHD18 {ECO:0000313|Ensembl:ENSP00000425434};+++[D6RGX5_HUMAN|Unreviewed]SubName: Full=Protein ABHD18 {ECO:0000313|Ensembl:ENSP00000421129}; Flags: Fragment;"]
[80185,"'TTI2'",219,168,220,202.333333333333,{"$nulls":4},"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0070209///ASTRA complex+++GO:0005654///nucleoplasm","GO:0003723///RNA binding","GO:0000470///maturation of LSU-rRNA+++GO:0000460///maturation of 5.8S rRNA","TELO2 interacting protein 2","[TTI2_HUMAN|Reviewed]RecName: Full=TELO2-interacting protein 2;+++[E5RHM7_HUMAN|Unreviewed]SubName: Full=TELO2-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000428569}; Flags: Fragment;+++[E5RIH5_HUMAN|Unreviewed]SubName: Full=TELO2-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000428401};"]
[80219,"'COQ10B'",198,264,229,230.333333333333,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0048039///ubiquinone binding","GO:0045333///cellular respiration+++GO:0006744///ubiquinone biosynthetic process","coenzyme Q10B","[CQ10B_HUMAN|Reviewed]RecName: Full=Coenzyme Q-binding protein COQ10 homolog B, mitochondrial; Flags: Precursor;+++[B8ZZV9_HUMAN|Unreviewed]SubName: Full=Coenzyme Q-binding protein COQ10 homolog B, mitochondrial {ECO:0000313|Ensembl:ENSP00000387223};+++[B8ZZX2_HUMAN|Unreviewed]SubName: Full=Coenzyme Q-binding protein COQ10 homolog B, mitochondrial {ECO:0000313|Ensembl:ENSP00000386785};"]
[80243,"'PREX2'",15,8,6,9.66666666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity","GO:0035023///regulation of Rho protein signal transduction+++GO:0035556///intracellular signal transduction+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0048813///dendrite morphogenesis+++GO:0008344///adult locomotory behavior","phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2","[PREX2_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein; Short=P-Rex2; Short=PtdIns(3,4,5)-dependent Rac exchanger 2; AltName: Full=DEP domain-containing protein 2;+++[A0A2X0SZ31_HUMAN|Unreviewed]SubName: Full=PREX2 {ECO:0000313|EMBL:SPT35789.1}; Flags: Fragment;+++[Q56UR8_HUMAN|Unreviewed]SubName: Full=PtdIns(3,4,5)-dependent rac exchanger-2 {ECO:0000313|EMBL:AAS59407.1}; Flags: Fragment;"]
[80303,"'EFHD1'",31,38,43,37.3333333333333,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0031175///neuron projection development","EF-hand domain family member D1","[EFHD1_HUMAN|Reviewed]RecName: Full=EF-hand domain-containing protein D1; AltName: Full=EF-hand domain-containing protein 1; AltName: Full=Swiprosin-2;+++[A0A024R493_HUMAN|Unreviewed]SubName: Full=EF-hand domain family, member D1, isoform CRA_a {ECO:0000313|EMBL:EAW71015.1};+++[A0A087X1Z2_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing protein D1 {ECO:0000313|Ensembl:ENSP00000484568};+++[C9JTV4_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing protein D1 {ECO:0000313|Ensembl:ENSP00000401073}; Flags: Fragment;+++[H7C0I0_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing protein D1 {ECO:0000313|Ensembl:ENSP00000395119}; Flags: Fragment;+++[Q7Z2R5_HUMAN|Unreviewed]SubName: Full=MSTP133 {ECO:0000313|EMBL:AAQ13667.1};+++[Q8WYH2_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing protein D1 {ECO:0000313|Ensembl:ENSP00000386243};"]
[80317,"'ZKSCAN3'",80.57,77,69.86,75.81,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010507///negative regulation of autophagy+++GO:0006914///autophagy+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000773///negative regulation of cellular senescence+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007040///lysosome organization","zinc finger with KRAB and SCAN domains 3","[ZKSC3_HUMAN|Reviewed]RecName: Full=Zinc finger protein with KRAB and SCAN domains 3; AltName: Full=Zinc finger and SCAN domain-containing protein 13; AltName: Full=Zinc finger protein 306; AltName: Full=Zinc finger protein 309; AltName: Full=Zinc finger protein 47 homolog; Short=Zf47; Short=Zfp-47;"]
[80345,"'ZSCAN16'",56,58,51,55,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and SCAN domain containing 16","[ZSC16_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 16; AltName: Full=Zinc finger protein 392; AltName: Full=Zinc finger protein 435;+++[B4DFB7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60044, highly similar to Zinc finger protein 435 {ECO:0000313|EMBL:BAG57378.1};"]
[8061,"'FOSL1'",139,211,235,195,"04310///Wnt signaling pathway+++04657///IL-17 signaling pathway+++05166///HTLV-I infection+++04380///Osteoclast differentiation",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0043005///neuron projection+++GO:0043231///intracellular membrane-bounded organelle+++GO:0042734///presynaptic membrane+++GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0042542///response to hydrogen peroxide+++GO:0051591///response to cAMP+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0045787///positive regulation of cell cycle+++GO:0006968///cellular defense response+++GO:0008285///negative regulation of cell proliferation+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0034097///response to cytokine+++GO:0006935///chemotaxis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007296///vitellogenesis+++GO:0006366///transcription by RNA polymerase II+++GO:0032570///response to progesterone+++GO:0042493///response to drug+++GO:0051412///response to corticosterone+++GO:0014070///response to organic cyclic compound+++GO:0031668///cellular response to extracellular stimulus+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:0060674///placenta blood vessel development+++GO:0009615///response to virus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007612///learning+++GO:0007565///female pregnancy+++GO:0001701///in utero embryonic development+++GO:0009629///response to gravity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0009612///response to mechanical stimulus+++GO:0043065///positive regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation","FOS like 1, AP-1 transcription factor subunit","[FOSL1_HUMAN|Reviewed]RecName: Full=Fos-related antigen 1; Short=FRA-1;+++[A0A0S2Z595_HUMAN|Unreviewed]SubName: Full=FOS-like antigen 1 isoform 1 {ECO:0000313|EMBL:ALQ33865.1}; Flags: Fragment;+++[E9PKL5_HUMAN|Unreviewed]SubName: Full=Fos-related antigen 1 {ECO:0000313|Ensembl:ENSP00000431594};+++[E9PPX2_HUMAN|Unreviewed]SubName: Full=FOS-like antigen 1 isoform 2 {ECO:0000313|EMBL:ALQ33866.1}; SubName: Full=Fos-related antigen 1 {ECO:0000313|Ensembl:ENSP00000436276};+++[E9PQT6_HUMAN|Unreviewed]SubName: Full=Fos-related antigen 1 {ECO:0000313|Ensembl:ENSP00000434350}; Flags: Fragment;"]
[80737,"'VWA7'",12,26,15.99,17.9966666666667,{"$nulls":4},"GO:0005575///cellular_component+++GO:0005576///extracellular region","GO:0003674///molecular_function","GO:0008150///biological_process","von Willebrand factor A domain containing 7","[VWA7_HUMAN|Reviewed]RecName: Full=von Willebrand factor A domain-containing protein 7; AltName: Full=Protein G7c; Flags: Precursor;+++[A0A140T9S5_HUMAN|Unreviewed]SubName: Full=VWA7 {ECO:0000313|EMBL:AQY77207.1}; SubName: Full=von Willebrand factor A domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000411804};+++[A0A1U9X8T7_HUMAN|Unreviewed]SubName: Full=VWA7 {ECO:0000313|EMBL:AQY77203.1};"]
[80774,"'LIMD2'",82,138,147,122.333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0046872///metal ion binding",null,"LIM domain containing 2","[LIMD2_HUMAN|Reviewed]RecName: Full=LIM domain-containing protein 2 {ECO:0000305};+++[A0A140VJN0_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 106 {ECO:0000313|EMBL:AEE61017.1};+++[J3KRR0_HUMAN|Unreviewed]SubName: Full=LIM domain containing 2, isoform CRA_b {ECO:0000313|EMBL:EAW94293.1}; SubName: Full=LIM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000462125};+++[J3QL69_HUMAN|Unreviewed]SubName: Full=LIM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000463409};+++[J3QQM5_HUMAN|Unreviewed]SubName: Full=LIM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000463805}; Flags: Fragment;"]
[80821,"'DDHD1'",176,159,117,150.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0052739///phosphatidylserine 1-acylhydrolase activity+++GO:0004620///phospholipase activity+++GO:0008970///phospholipase A1 activity+++GO:0016787///hydrolase activity+++GO:0052740///1-acyl-2-lysophosphatidylserine acylhydrolase activity","GO:0090141///positive regulation of mitochondrial fission+++GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process","DDHD domain containing 1","[DDHD1_HUMAN|Reviewed]RecName: Full=Phospholipase DDHD1; EC=3.1.1.-; AltName: Full=DDHD domain-containing protein 1; AltName: Full=Phosphatidic acid-preferring phospholipase A1 homolog; Short=PA-PLA1;+++[A0A087X0H7_HUMAN|Unreviewed]SubName: Full=Phospholipase DDHD1 {ECO:0000313|Ensembl:ENSP00000483405};+++[D3K5P3_HUMAN|Unreviewed]SubName: Full=Phosphatidic acid-preferring phospholipase A1 splice variant 2 {ECO:0000313|EMBL:ADB80245.1}; EC=3.1.1.32 {ECO:0000313|EMBL:ADB80245.1};+++[G3V2P6_HUMAN|Unreviewed]SubName: Full=Phospholipase DDHD1 {ECO:0000313|Ensembl:ENSP00000450785}; Flags: Fragment;"]
[80864,"'EGFL8'",41,54,45,46.6666666666667,{"$nulls":4},"GO:0005576///extracellular region+++GO:0009986///cell surface","GO:0005102///signaling receptor binding+++GO:0005509///calcium ion binding","GO:0001701///in utero embryonic development+++GO:0048856///anatomical structure development","EGF like domain multiple 8","[EGFL8_HUMAN|Reviewed]RecName: Full=Epidermal growth factor-like protein 8; Short=EGF-like protein 8; AltName: Full=Vascular endothelial statin-2; Short=VE-statin-2; Flags: Precursor;+++[A0A140T9I6_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor-like protein 8 {ECO:0000313|Ensembl:ENSP00000404259}; Flags: Fragment;+++[A0A1U9X7N9_HUMAN|Unreviewed]SubName: Full=EGFL8 {ECO:0000313|EMBL:AQY76805.1};+++[Q5JP22_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor-like protein 8 {ECO:0000313|Ensembl:ENSP00000401694}; Flags: Fragment;"]
[81037,"'CLPTM1L'",2423,2715,2698,2612,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:0006915///apoptotic process","CLPTM1 like","[CLP1L_HUMAN|Reviewed]RecName: Full=Cleft lip and palate transmembrane protein 1-like protein; Short=CLPTM1-like protein; AltName: Full=Cisplatin resistance-related protein 9; Short=CRR9p;+++[G5E9Z2_HUMAN|Unreviewed]SubName: Full=Cisplatin resistance related protein CRR9p, isoform CRA_c {ECO:0000313|EMBL:EAX08164.1}; SubName: Full=Cleft lip and palate transmembrane protein 1-like protein {ECO:0000313|Ensembl:ENSP00000423321};"]
[8140,"'SLC7A5'",21076.1,14553.23,17883.02,17837.45,"05230///Central carbon metabolism in cancer+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016324///apical plasma membrane","GO:0015171///amino acid transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0042605///peptide antigen binding+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0005515///protein binding","GO:1902475///L-alpha-amino acid transmembrane transport+++GO:0015804///neutral amino acid transport+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0003333///amino acid transmembrane transport+++GO:0015807///L-amino acid transport+++GO:0006865///amino acid transport+++GO:0050900///leukocyte migration+++GO:0006520///cellular amino acid metabolic process+++GO:0007399///nervous system development+++GO:0055085///transmembrane transport","solute carrier family 7 member 5","[LAT1_HUMAN|Reviewed]RecName: Full=Large neutral amino acids transporter small subunit 1; AltName: Full=4F2 light chain; Short=4F2 LC; Short=4F2LC; AltName: Full=CD98 light chain; AltName: Full=Integral membrane protein E16; AltName: Full=L-type amino acid transporter 1; Short=hLAT1; AltName: Full=Solute carrier family 7 member 5; AltName: Full=y+ system cationic amino acid transporter;+++[A0A0C4DGL4_HUMAN|Unreviewed]SubName: Full=Large neutral amino acids transporter small subunit 1 {ECO:0000313|Ensembl:ENSP00000454323}; SubName: Full=Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 5, isoform CRA_b {ECO:0000313|EMBL:EAW95374.1};+++[Q2MCL6_HUMAN|Unreviewed]SubName: Full=Large neutral amino acids transporter 1 {ECO:0000313|EMBL:CAJ58680.1}; Flags: Fragment;"]
[81553,"'FAM49A'",66,66,43,58.3333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005622///intracellular","GO:0003727///single-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0003697///single-stranded DNA binding+++GO:0042802///identical protein binding","GO:0032197///transposition, RNA-mediated","family with sequence similarity 49 member A","[FA49A_HUMAN|Reviewed]RecName: Full=Protein FAM49A;+++[C9IYV6_HUMAN|Unreviewed]SubName: Full=Protein FAM49A {ECO:0000313|Ensembl:ENSP00000392154}; Flags: Fragment;+++[C9JPE5_HUMAN|Unreviewed]SubName: Full=Protein FAM49A {ECO:0000313|Ensembl:ENSP00000388979}; Flags: Fragment;"]
[81572,"'PDRG1'",100,149,122,123.666666666667,{"$nulls":4},"GO:0016272///prefoldin complex+++GO:0005737///cytoplasm","GO:0051082///unfolded protein binding","GO:0006457///protein folding","p53 and DNA damage regulated 1","[PDRG1_HUMAN|Reviewed]RecName: Full=p53 and DNA damage-regulated protein 1;"]
[81577,"'GFOD2'",376,455,502.15,444.383333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region","GO:0016491///oxidoreductase activity","GO:0030198///extracellular matrix organization+++GO:0055114///oxidation-reduction process","glucose-fructose oxidoreductase domain containing 2","[GFOD2_HUMAN|Reviewed]RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 2; EC=1.-.-.-; Flags: Precursor;+++[A0A087WT49_HUMAN|Unreviewed]SubName: Full=Glucose-fructose oxidoreductase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000477581};+++[A0A087WTD9_HUMAN|Unreviewed]SubName: Full=Glucose-fructose oxidoreductase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000477784};+++[A0A087X156_HUMAN|Unreviewed]SubName: Full=Glucose-fructose oxidoreductase domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000483913}; Flags: Fragment;"]
[81669,"'CCNL2'",1341,1562,1363,1422,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity","cyclin L2","[CCNL2_HUMAN|Reviewed]RecName: Full=Cyclin-L2; AltName: Full=Paneth cell-enhanced expression protein;+++[A0A0A0MSF3_HUMAN|Unreviewed]SubName: Full=Cyclin-L2 {ECO:0000313|Ensembl:ENSP00000386132};+++[C9J148_HUMAN|Unreviewed]SubName: Full=Cyclin-L2 {ECO:0000313|Ensembl:ENSP00000392899};+++[J3KRL1_HUMAN|Unreviewed]SubName: Full=Cyclin-L2 {ECO:0000313|Ensembl:ENSP00000462056}; Flags: Fragment;+++[J3QSH2_HUMAN|Unreviewed]SubName: Full=Cyclin-L2 {ECO:0000313|Ensembl:ENSP00000464685}; Flags: Fragment;"]
[81693,"'AMN'",2,2,10,4.66666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01277///Vitamin B12 deficiency anaemia",null,null,"GO:0016324///apical plasma membrane+++GO:0005856///cytoskeleton+++GO:0042641///actomyosin+++GO:0032991///protein-containing complex+++GO:0005905///clathrin-coated pit+++GO:0031526///brush border membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction+++GO:0030027///lamellipodium+++GO:0010008///endosome membrane+++GO:0030139///endocytic vesicle+++GO:0070062///extracellular exosome+++GO:0031252///cell leading edge+++GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0017048///Rho GTPase binding+++GO:0000287///magnesium ion binding+++GO:0044877///protein-containing complex binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005102///signaling receptor binding+++GO:0005524///ATP binding","GO:0031532///actin cytoskeleton reorganization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0031032///actomyosin structure organization+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0007165///signal transduction+++GO:0016477///cell migration+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0015889///cobalamin transport+++GO:0006468///protein phosphorylation+++GO:0009235///cobalamin metabolic process+++GO:0007588///excretion+++GO:0006898///receptor-mediated endocytosis+++GO:0035556///intracellular signal transduction+++GO:0032197///transposition, RNA-mediated+++GO:0034384///high-density lipoprotein particle clearance+++GO:0007010///cytoskeleton organization+++GO:0007275///multicellular organism development","amnion associated transmembrane protein","[AMNLS_HUMAN|Reviewed]RecName: Full=Protein amnionless; Flags: Precursor;+++[B3KP64_HUMAN|Unreviewed]SubName: Full=Amnionless homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW81798.1}; SubName: Full=cDNA FLJ31240 fis, clone KIDNE2004981, highly similar to Amnionless protein {ECO:0000313|EMBL:BAG51576.1};+++[H0YKJ5_HUMAN|Unreviewed]SubName: Full=Protein amnionless {ECO:0000313|Ensembl:ENSP00000452831}; Flags: Fragment;+++[H0YMX8_HUMAN|Unreviewed]SubName: Full=Protein amnionless {ECO:0000313|Ensembl:ENSP00000453786}; Flags: Fragment;"]
[81855,"'SFXN3'",1316,1458,1581,1451.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0015075///ion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0055072///iron ion homeostasis+++GO:0006811///ion transport","sideroflexin 3","[SFXN3_HUMAN|Reviewed]RecName: Full=Sideroflexin-3;+++[A0A0A0MS41_HUMAN|Unreviewed]RecName: Full=Sideroflexin {ECO:0000256|RuleBase:RU362000};+++[A0A1P0AYU5_HUMAN|Unreviewed]RecName: Full=Sideroflexin {ECO:0000256|RuleBase:RU362000};+++[S4R3N9_HUMAN|Unreviewed]SubName: Full=Sideroflexin-3 {ECO:0000313|Ensembl:ENSP00000474564};"]
[81873,"'ARPC5L'",175,234,237,215.333333333333,"05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++05131///Shigellosis+++04144///Endocytosis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0005885///Arp2/3 protein complex+++GO:0005856///cytoskeleton+++GO:0098978///glutamatergic synapse+++GO:0045202///synapse","GO:0003674///molecular_function+++GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding","GO:0030833///regulation of actin filament polymerization+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0008150///biological_process+++GO:0016477///cell migration","actin related protein 2/3 complex subunit 5 like","[ARP5L_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5-like protein; AltName: Full=Arp2/3 complex 16 kDa subunit 2; Short=ARC16-2;+++[A0A024R897_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};+++[B3KPC7_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};"]
[8209,"'GATD3A'",363.23,364.61,339.8,355.88,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0071820///N-box binding+++GO:0046983///protein dimerization activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0070888///E-box binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0051087///chaperone binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060675///ureteric bud morphogenesis+++GO:0060253///negative regulation of glial cell proliferation+++GO:0016477///cell migration+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007155///cell adhesion+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0045607///regulation of inner ear auditory receptor cell differentiation+++GO:0021983///pituitary gland development+++GO:0060122///inner ear receptor cell stereocilium organization+++GO:2000974///negative regulation of pro-B cell differentiation+++GO:0035019///somatic stem cell population maintenance+++GO:0061626///pharyngeal arch artery morphogenesis+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0050678///regulation of epithelial cell proliferation+++GO:0030901///midbrain development+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048505///regulation of timing of cell differentiation+++GO:0042491///inner ear auditory receptor cell differentiation+++GO:0061009///common bile duct development+++GO:0001701///in utero embryonic development+++GO:0042668///auditory receptor cell fate determination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0090162///establishment of epithelial cell polarity+++GO:0048844///artery morphogenesis+++GO:0030324///lung development+++GO:0003151///outflow tract morphogenesis+++GO:0046425///regulation of JAK-STAT cascade+++GO:0045598///regulation of fat cell differentiation+++GO:0001889///liver development+++GO:0048469///cell maturation+++GO:0035910///ascending aorta morphogenesis+++GO:0031016///pancreas development+++GO:0030513///positive regulation of BMP signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0050767///regulation of neurogenesis+++GO:0072141///renal interstitial fibroblast development+++GO:0030154///cell differentiation+++GO:0046427///positive regulation of JAK-STAT cascade+++GO:0021558///trochlear nerve development+++GO:0045665///negative regulation of neuron differentiation+++GO:0003266///regulation of secondary heart field cardioblast proliferation+++GO:0021555///midbrain-hindbrain boundary morphogenesis+++GO:0021861///forebrain radial glial cell differentiation+++GO:0007389///pattern specification process+++GO:0048538///thymus development+++GO:0021915///neural tube development+++GO:2000737///negative regulation of stem cell differentiation+++GO:0097150///neuronal stem cell population maintenance+++GO:0021575///hindbrain morphogenesis+++GO:0007224///smoothened signaling pathway+++GO:0060164///regulation of timing of neuron differentiation+++GO:0045977///positive regulation of mitotic cell cycle, embryonic+++GO:0021984///adenohypophysis development+++GO:0065003///protein-containing complex assembly+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0021557///oculomotor nerve development+++GO:0008284///positive regulation of cell proliferation+++GO:0061309///cardiac neural crest cell development involved in outflow tract morphogenesis+++GO:0045608///negative regulation of inner ear auditory receptor cell differentiation+++GO:0060412///ventricular septum morphogenesis+++GO:0072049///comma-shaped body morphogenesis+++GO:0090102///cochlea development+++GO:0045596///negative regulation of cell differentiation+++GO:2000227///negative regulation of pancreatic A cell differentiation+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0061106///negative regulation of stomach neuroendocrine cell differentiation+++GO:0007399///nervous system development+++GO:0072012///glomerulus vasculature development+++GO:0003143///embryonic heart tube morphogenesis+++GO:2000978///negative regulation of forebrain neuron differentiation+++GO:2000981///negative regulation of inner ear receptor cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0072050///S-shaped body morphogenesis+++GO:0001756///somitogenesis+++GO:0045165///cell fate commitment+++GO:0003281///ventricular septum development+++GO:0043388///positive regulation of DNA binding+++GO:0097084///vascular smooth muscle cell development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0021537///telencephalon development+++GO:0007219///Notch signaling pathway+++GO:0046331///lateral inhibition+++GO:0035909///aorta morphogenesis+++GO:0072282///metanephric nephron tubule morphogenesis+++GO:0060716///labyrinthine layer blood vessel development","glutamine amidotransferase like class 1 domain containing 3A","[GAL3A_HUMAN|Reviewed]RecName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000305}; Flags: Precursor;+++[GAL3B_HUMAN|Reviewed]RecName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial; AltName: Full=Keio novel protein-I {ECO:0000303|PubMed:8753807}; Short=KNP-I {ECO:0000303|PubMed:8753807}; AltName: Full=Protein GT335 {ECO:0000303|PubMed:8975701}; AltName: Full=Protein HES1 {ECO:0000303|PubMed:9150728}; Flags: Precursor;+++[A0A096LNH5_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000483086};+++[A0A140VKB0_HUMAN|Unreviewed]SubName: Full=Testis secretory sperm-binding protein Li 237E {ECO:0000313|EMBL:AEE61247.1};+++[A0A2R8Y588_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000494347};+++[A0A2R8Y6K9_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000495305};+++[A0A2R8YDR7_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000494853}; Flags: Fragment;+++[F2Z2Q0_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000396655};+++[H7C1F6_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000400044}; Flags: Fragment;+++[H7C2G3_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000405713}; Flags: Fragment;+++[Q8IXV0_HUMAN|Unreviewed]SubName: Full=HES1 protein {ECO:0000313|EMBL:AAH39152.1};"]
[8226,"'PUDP'",137,130,172,146.333333333333,"04140///Autophagy - animal+++00140///Steroid hormone biosynthesis+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome+++H00134///X-linked ichthyosis (XLI)",null,"R11180///pseudouridine-5'-phosphate phosphohydrolase   Pseudouridine 5'-phosphate + H2O <=> Pseudouridine + Orthophosphate","GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:1990738///pseudouridine 5'-phosphatase activity+++GO:0016787///hydrolase activity+++GO:0000287///magnesium ion binding+++GO:0003674///molecular_function","GO:0009117///nucleotide metabolic process+++GO:0008150///biological_process+++GO:0043097///pyrimidine nucleoside salvage+++GO:0016311///dephosphorylation","pseudouridine 5'-phosphatase","[HDHD1_HUMAN|Reviewed]RecName: Full=Pseudouridine-5'-phosphatase {ECO:0000312|HGNC:HGNC:16818}; EC=3.1.3.96; AltName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 1; AltName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 1A; AltName: Full=Protein GS1; AltName: Full=Pseudouridine-5'-monophosphatase; Short=5'-PsiMPase;+++[E7EVH9_HUMAN|Unreviewed]SubName: Full=Pseudouridine-5'-phosphatase {ECO:0000313|Ensembl:ENSP00000430995}; Flags: Fragment;"]
[8242,"'KDM5C'",1801,1712,1605,1706,null,"H00658///Syndromic X-linked mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0035097///histone methyltransferase complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0032452///histone demethylase activity+++GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0051213///dioxygenase activity+++GO:0035064///methylated histone binding+++GO:0003677///DNA binding+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0006325///chromatin organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0034720///histone H3-K4 demethylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific","lysine demethylase 5C","[KDM5C_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 5C; EC=1.14.11.-; AltName: Full=Histone demethylase JARID1C; AltName: Full=Jumonji/ARID domain-containing protein 1C {ECO:0000303|PubMed:19636912}; AltName: Full=Protein SmcX {ECO:0000303|PubMed:19636912}; AltName: Full=Protein Xe169;+++[A6N6J7_HUMAN|Unreviewed]SubName: Full=JARID1C protein {ECO:0000313|EMBL:ABR13544.1};+++[F8W7H7_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5C {ECO:0000313|Ensembl:ENSP00000344004};+++[F8WDK1_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5C {ECO:0000313|Ensembl:ENSP00000409757};+++[F8WF56_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5C {ECO:0000313|Ensembl:ENSP00000407277};+++[L8E945_HUMAN|Unreviewed]SubName: Full=Alternative protein KDM5C {ECO:0000313|EMBL:CCQ43251.1};"]
[8309,"'ACOX2'",415,378,322,371.666666666667,"04146///Peroxisome+++03320///PPAR signaling pathway+++00120///Primary bile acid biosynthesis+++01100///Metabolic pathways","H00628///Congenital bile acid synthesis defect (CBAS)","M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R08735///(25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24,25-oxidoreductase   (25S)-3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-oyl-CoA + Acceptor <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor+++R08740///(25S)-3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA:acceptor 24,25-oxidoreductase   (25S)-3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA + Acceptor <=> 3alpha,7alpha-Dihydroxy-5beta-cholest-24-enoyl-CoA + Reduced acceptor","GO:0005782///peroxisomal matrix+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle","GO:0003997///acyl-CoA oxidase activity+++GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0071949///FAD binding+++GO:0005504///fatty acid binding+++GO:0042803///protein homodimerization activity+++GO:0005102///signaling receptor binding+++GO:0016402///pristanoyl-CoA oxidase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0033791///3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity","GO:0006631///fatty acid metabolic process+++GO:1902884///positive regulation of response to oxidative stress+++GO:0006699///bile acid biosynthetic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0006635///fatty acid beta-oxidation+++GO:0006629///lipid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006625///protein targeting to peroxisome+++GO:0055088///lipid homeostasis+++GO:0010942///positive regulation of cell death","acyl-CoA oxidase 2","[ACOX2_HUMAN|Reviewed]RecName: Full=Peroxisomal acyl-coenzyme A oxidase 2 {ECO:0000303|PubMed:14702039}; EC=1.17.99.3 {ECO:0000269|PubMed:27884763}; AltName: Full=3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; AltName: Full=3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase {ECO:0000250|UniProtKB:O02767}; AltName: Full=Trihydroxycoprostanoyl-CoA oxidase {ECO:0000250|UniProtKB:P97562}; Short=THCA-CoA oxidase {ECO:0000250|UniProtKB:O02767}; Short=THCCox;+++[C9J0G0_HUMAN|Unreviewed]RecName: Full=Acyl-coenzyme A oxidase {ECO:0000256|PIRNR:PIRNR000168};+++[C9JY29_HUMAN|Unreviewed]SubName: Full=Peroxisomal acyl-coenzyme A oxidase 2 {ECO:0000313|Ensembl:ENSP00000419927}; Flags: Fragment;+++[H7C4Q2_HUMAN|Unreviewed]SubName: Full=Peroxisomal acyl-coenzyme A oxidase 2 {ECO:0000313|Ensembl:ENSP00000417877}; Flags: Fragment;+++[H7C4Y2_HUMAN|Unreviewed]SubName: Full=Peroxisomal acyl-coenzyme A oxidase 2 {ECO:0000313|Ensembl:ENSP00000418515}; Flags: Fragment;+++[H7C573_HUMAN|Unreviewed]SubName: Full=Peroxisomal acyl-coenzyme A oxidase 2 {ECO:0000313|Ensembl:ENSP00000419133}; Flags: Fragment;"]
[8318,"'CDC45'",4,6,2,4,"04113///Meiosis - yeast+++04110///Cell cycle+++04111///Cell cycle - yeast","H01889///Meier-Gorlin syndrome",null,null,"GO:0005656///nuclear pre-replicative complex+++GO:0031298///replication fork protection complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0031261///DNA replication preinitiation complex","GO:0043138///3'-5' DNA helicase activity+++GO:0005515///protein binding+++GO:0003697///single-stranded DNA binding+++GO:0003682///chromatin binding+++GO:0003688///DNA replication origin binding","GO:0031938///regulation of chromatin silencing at telomere+++GO:1902977///mitotic DNA replication preinitiation complex assembly+++GO:0006270///DNA replication initiation+++GO:0000076///DNA replication checkpoint+++GO:0032508///DNA duplex unwinding+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0006260///DNA replication+++GO:0000727///double-strand break repair via break-induced replication+++GO:0006267///pre-replicative complex assembly involved in nuclear cell cycle DNA replication","cell division cycle 45","[CDC45_HUMAN|Reviewed]RecName: Full=Cell division control protein 45 homolog; AltName: Full=PORC-PI-1;+++[C9J911_HUMAN|Unreviewed]SubName: Full=Cell division control protein 45 homolog {ECO:0000313|Ensembl:ENSP00000397434}; Flags: Fragment;+++[C9K087_HUMAN|Unreviewed]SubName: Full=Cell division control protein 45 homolog {ECO:0000313|Ensembl:ENSP00000413138}; Flags: Fragment;+++[H7BZ91_HUMAN|Unreviewed]SubName: Full=Cell division control protein 45 homolog {ECO:0000313|Ensembl:ENSP00000388280}; Flags: Fragment;"]
[83440,"'ADPGK'",843,783,800,808.666666666667,"01130///Biosynthesis of antibiotics+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis+++01200///Carbon metabolism+++01100///Metabolic pathways",null,"M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate","R09085///ADP:D-glucose 6-phosphotransferase   alpha-D-Glucose + ADP <=> alpha-D-Glucose 6-phosphate + AMP+++R05804///ADP:D-glucose 6-phosphotransferase   ADP + D-Glucose <=> AMP + D-Glucose 6-phosphate+++R09086///ADP:D-glucose 6-phosphotransferase   beta-D-Glucose + ADP <=> beta-D-Glucose 6-phosphate + AMP","GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0043843///ADP-specific glucokinase activity","GO:0016310///phosphorylation+++GO:0061621///canonical glycolysis+++GO:0006096///glycolytic process+++GO:0006006///glucose metabolic process+++GO:0005975///carbohydrate metabolic process","ADP dependent glucokinase","[ADPGK_HUMAN|Reviewed]RecName: Full=ADP-dependent glucokinase; Short=ADP-GK; Short=ADPGK; EC=2.7.1.147; AltName: Full=RbBP-35; Flags: Precursor;+++[H3BN66_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase, isoform CRA_e {ECO:0000313|EMBL:EAW77918.1};+++[H3BRS6_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000456387}; Flags: Fragment;+++[H3BTH4_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000457175}; Flags: Fragment;+++[H3BU35_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000457447}; Flags: Fragment;+++[H3BUC3_HUMAN|Unreviewed]SubName: Full=ADP-dependent glucokinase {ECO:0000313|Ensembl:ENSP00000457572}; Flags: Fragment;"]
[8345,"'HIST1H2BH'",0,1,2,1,"05322///Systemic lupus erythematosus+++05034///Alcoholism+++05203///Viral carcinogenesis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0000786///nucleosome+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046982///protein heterodimerization activity+++GO:0019899///enzyme binding+++GO:0097677///STAT family protein binding","GO:0006334///nucleosome assembly+++GO:0016567///protein ubiquitination","histone cluster 1 H2B family member h","[H2B1H_HUMAN|Reviewed]RecName: Full=Histone H2B type 1-H; AltName: Full=Histone H2B.j; Short=H2B/j;"]
[83546,"'RTBDN'",0,0,1,0.333333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0033165///interphotoreceptor matrix+++GO:0031362///anchored component of external side of plasma membrane+++GO:0005576///extracellular region","GO:0032217///riboflavin transmembrane transporter activity+++GO:1902444///riboflavin binding+++GO:0038023///signaling receptor activity","GO:0032218///riboflavin transport","retbindin","[RTBDN_HUMAN|Reviewed]RecName: Full=Retbindin; Flags: Precursor;+++[K7EIS2_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000464869}; Flags: Fragment;+++[K7EKV3_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000465796}; Flags: Fragment;+++[K7EM70_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000466382}; Flags: Fragment;+++[K7EN64_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000466805}; Flags: Fragment;+++[K7ENA4_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000466855}; Flags: Fragment;+++[K7EQL9_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000467888}; Flags: Fragment;+++[K7ES48_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000468552}; Flags: Fragment;+++[K7ESG0_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000468697};+++[K7ESL8_HUMAN|Unreviewed]SubName: Full=Retbindin {ECO:0000313|Ensembl:ENSP00000468769}; Flags: Fragment;+++[Q8N210_HUMAN|Unreviewed]SubName: Full=Retbindin, isoform CRA_c {ECO:0000313|EMBL:EAW84316.1}; SubName: Full=cDNA FLJ36353 fis, clone THYMU2007307 {ECO:0000313|EMBL:BAC04217.1};"]
[83607,"'AMMECR1L'",403,415,387,401.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","AMMECR1 like","[AMERL_HUMAN|Reviewed]RecName: Full=AMMECR1-like protein;+++[A0A024RAG1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW95347.1};"]
[83637,"'ZMIZ2'",4470,4931,4681,4694,{"$nulls":4},"GO:0043596///nuclear replication fork+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008270///zinc ion binding","GO:0045944///positive regulation of transcription by RNA polymerase II","zinc finger MIZ-type containing 2","[ZMIZ2_HUMAN|Reviewed]RecName: Full=Zinc finger MIZ domain-containing protein 2; AltName: Full=PIAS-like protein Zimp7;+++[A0A087X127_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000483853};+++[A3KMG8_HUMAN|Unreviewed]SubName: Full=ZMIZ2 protein {ECO:0000313|EMBL:AAI31781.1}; Flags: Fragment;+++[C9JDA5_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415501}; Flags: Fragment;+++[D4YW75_HUMAN|Unreviewed]SubName: Full=TRAFIP20 {ECO:0000313|EMBL:AAQ15172.1};+++[E7EWM3_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000396601};+++[F8WC48_HUMAN|Unreviewed]SubName: Full=Zinc finger MIZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000406820};"]
[83658,"'DYNLRB1'",2226,2369,2596,2397,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0097542///ciliary tip+++GO:0005868///cytoplasmic dynein complex+++GO:0005737///cytoplasm+++GO:0005929///cilium+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0005874///microtubule+++GO:0030286///dynein complex+++GO:0036157///outer dynein arm","GO:0005515///protein binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0045505///dynein intermediate chain binding","GO:0035735///intraciliary transport involved in cilium assembly+++GO:0009416///response to light stimulus+++GO:0007018///microtubule-based movement+++GO:0007632///visual behavior","dynein light chain roadblock-type 1","[DLRB1_HUMAN|Reviewed]RecName: Full=Dynein light chain roadblock-type 1; AltName: Full=Bithoraxoid-like protein; Short=BLP; AltName: Full=Dynein light chain 2A, cytoplasmic; AltName: Full=Dynein-associated protein Km23; AltName: Full=Roadblock domain-containing protein 1;+++[B1AKR6_HUMAN|Unreviewed]SubName: Full=Dynein light chain roadblock-type 1 {ECO:0000313|Ensembl:ENSP00000363979};+++[B4DFR2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59194, moderately similar to Dynein light chain 2A, cytoplasmic {ECO:0000313|EMBL:BAG57523.1};"]
[83716,"'CRISPLD2'",703,808,554,688.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0030133///transport vesicle+++GO:0034774///secretory granule lumen+++GO:1904813///ficolin-1-rich granule lumen","GO:0005539///glycosaminoglycan binding+++GO:0008201///heparin binding","GO:0043312///neutrophil degranulation+++GO:0060325///face morphogenesis+++GO:0030324///lung development+++GO:0030198///extracellular matrix organization","cysteine rich secretory protein LCCL domain containing 2","[CRLD2_HUMAN|Reviewed]RecName: Full=Cysteine-rich secretory protein LCCL domain-containing 2; AltName: Full=Cysteine-rich secretory protein 11; Short=CRISP-11; AltName: Full=LCCL domain-containing cysteine-rich secretory protein 2; Flags: Precursor;+++[A0A140VK80_HUMAN|Unreviewed]SubName: Full=Testis secretory sperm-binding protein Li 207a {ECO:0000313|EMBL:AEE61217.1};+++[H3BS62_HUMAN|Unreviewed]SubName: Full=Cysteine-rich secretory protein LCCL domain-containing 2 {ECO:0000313|Ensembl:ENSP00000456554}; Flags: Fragment;+++[H3BSZ9_HUMAN|Unreviewed]SubName: Full=Cysteine-rich secretory protein LCCL domain-containing 2 {ECO:0000313|Ensembl:ENSP00000456952}; Flags: Fragment;+++[H3BTI0_HUMAN|Unreviewed]SubName: Full=Cysteine-rich secretory protein LCCL domain-containing 2 {ECO:0000313|Ensembl:ENSP00000457183};+++[H3BTP0_HUMAN|Unreviewed]SubName: Full=Cysteine-rich secretory protein LCCL domain-containing 2 {ECO:0000313|Ensembl:ENSP00000457259}; Flags: Fragment;+++[J3QKP2_HUMAN|Unreviewed]SubName: Full=Cysteine-rich secretory protein LCCL domain-containing 2 {ECO:0000313|Ensembl:ENSP00000463171}; Flags: Fragment;"]
[83746,"'L3MBTL2'",695,722,729,715.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0035064///methylated histone binding+++GO:0005515///protein binding+++GO:0042393///histone binding","GO:0006325///chromatin organization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0070317///negative regulation of G0 to G1 transition","L3MBTL2, polycomb repressive complex 1 subunit","[LMBL2_HUMAN|Reviewed]RecName: Full=Lethal(3)malignant brain tumor-like protein 2; Short=H-l(3)mbt-like protein 2; Short=L(3)mbt-like protein 2;+++[A0A0S2Z5Q2_HUMAN|Unreviewed]SubName: Full=Lmbt-like 2 (Drosophila) isoform 2 {ECO:0000313|EMBL:ALQ34258.1};+++[A0A0S2Z5X6_HUMAN|Unreviewed]SubName: Full=L(3)mbt-like 2 (Drosophila), isoform CRA_e {ECO:0000313|EMBL:EAW60414.1}; SubName: Full=Lmbt-like 2 (Drosophila) isoform 1 {ECO:0000313|EMBL:ALQ34257.1}; Flags: Fragment;+++[F8WBL1_HUMAN|Unreviewed]SubName: Full=Lethal(3)malignant brain tumor-like protein 2 {ECO:0000313|Ensembl:ENSP00000405849};+++[H0Y5M2_HUMAN|Unreviewed]SubName: Full=Lethal(3)malignant brain tumor-like protein 2 {ECO:0000313|Ensembl:ENSP00000399405}; Flags: Fragment;+++[H7C228_HUMAN|Unreviewed]SubName: Full=Lethal(3)malignant brain tumor-like protein 2 {ECO:0000313|Ensembl:ENSP00000403767}; Flags: Fragment;"]
[83856,"'FSD1L'",45,52,24,40.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","fibronectin type III and SPRY domain containing 1 like","[FSD1L_HUMAN|Reviewed]RecName: Full=FSD1-like protein; AltName: Full=Coiled-coil domain-containing protein 10; AltName: Full=FSD1 N-terminal-like protein;+++[A0A0A0MRS5_HUMAN|Unreviewed]SubName: Full=FSD1-like protein {ECO:0000313|Ensembl:ENSP00000363842};+++[A0A0C4DG97_HUMAN|Unreviewed]SubName: Full=FSD1-like protein {ECO:0000313|Ensembl:ENSP00000419691};+++[B7Z3W5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57313, highly similar to Homo sapiens fibronectin type III and SPRY domain containing 1-like, transcript variant 1, mRNA {ECO:0000313|EMBL:BAH12351.1};+++[C9JD05_HUMAN|Unreviewed]SubName: Full=FSD1-like protein {ECO:0000313|Ensembl:ENSP00000420624};+++[F8W946_HUMAN|Unreviewed]SubName: Full=FSD1-like protein {ECO:0000313|Ensembl:ENSP00000378384};+++[Q8N450_HUMAN|Unreviewed]SubName: Full=FSD1-like protein {ECO:0000313|Ensembl:ENSP00000363839}; SubName: Full=FSD1L protein {ECO:0000313|EMBL:AAH36746.1};"]
[83882,"'TSPAN10'",11987,11346,12686,12006.3333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0019899///enzyme binding","GO:0072594///establishment of protein localization to organelle+++GO:0007166///cell surface receptor signaling pathway","tetraspanin 10","[TSN10_HUMAN|Reviewed]RecName: Full=Tetraspanin-10; Short=Tspan-10; AltName: Full=Oculospanin;+++[A0A087WWT4_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[A0A087X235_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[F1T0E7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[F1T0E8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[Q6PJ65_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};"]
[8394,"'PIP5K1A'",1109,1110,934,1051,"04072///Phospholipase D signaling pathway+++00562///Inositol phosphate metabolism+++04810///Regulation of actin cytoskeleton+++04011///MAPK signaling pathway - yeast+++05231///Choline metabolism in cancer+++04144///Endocytosis+++04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways+++04666///Fc gamma R-mediated phagocytosis+++04139///Mitophagy - yeast","H00865///Lethal congenital contractural syndrome (LCCS)","M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R03469///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase   ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate","GO:0005829///cytosol+++GO:0032587///ruffle membrane+++GO:0005634///nucleus+++GO:0001726///ruffle+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0042995///cell projection+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005654///nucleoplasm+++GO:0030027///lamellipodium+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0052810///1-phosphatidylinositol-5-kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0000166///nucleotide binding+++GO:0019900///kinase binding+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0000285///1-phosphatidylinositol-3-phosphate 5-kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity+++GO:0052811///1-phosphatidylinositol-3-phosphate 4-kinase activity","GO:0046854///phosphatidylinositol phosphorylation+++GO:0010761///fibroblast migration+++GO:0016310///phosphorylation+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0090630///activation of GTPase activity+++GO:0007165///signal transduction+++GO:0048041///focal adhesion assembly+++GO:0008654///phospholipid biosynthetic process+++GO:0097178///ruffle assembly+++GO:0030216///keratinocyte differentiation+++GO:0046488///phosphatidylinositol metabolic process+++GO:0060326///cell chemotaxis+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006650///glycerophospholipid metabolic process+++GO:0006909///phagocytosis+++GO:0031532///actin cytoskeleton reorganization+++GO:0016477///cell migration+++GO:0072659///protein localization to plasma membrane","phosphatidylinositol-4-phosphate 5-kinase type 1 alpha","[PI51A_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; Short=PIP5K1-alpha; Short=PtdIns(4)P-5-kinase 1 alpha; EC=2.7.1.68; AltName: Full=68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; AltName: Full=Phosphatidylinositol 4-phosphate 5-kinase type I alpha; Short=PIP5KIalpha;+++[A2A5X0_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha {ECO:0000313|Ensembl:ENSP00000401228}; Flags: Fragment;+++[A6PW56_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha {ECO:0000313|Ensembl:ENSP00000392780}; Flags: Fragment;+++[A6PW57_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha {ECO:0000313|Ensembl:ENSP00000386432};+++[A6PW58_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha {ECO:0000313|Ensembl:ENSP00000414632}; Flags: Fragment;+++[E9PSF8_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha {ECO:0000313|Ensembl:ENSP00000416196};"]
[83990,"'BRIP1'",56.01,62.29,34.06,50.7866666666667,"03440///Homologous recombination+++03460///Fanconi anemia pathway","H00238///Fanconi anemia",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0020037///heme binding+++GO:0005515///protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006281///DNA repair+++GO:0000117///regulation of transcription involved in G2/M transition of mitotic cell cycle","BRCA1 interacting protein C-terminal helicase 1","[FANCJ_HUMAN|Reviewed]RecName: Full=Fanconi anemia group J protein; Short=Protein FACJ; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase BRIP1; AltName: Full=BRCA1-associated C-terminal helicase 1; AltName: Full=BRCA1-interacting protein C-terminal helicase 1; Short=BRCA1-interacting protein 1;+++[C9IYH8_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000392202}; Flags: Fragment;+++[C9IYR0_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000400576}; Flags: Fragment;+++[C9JMP6_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000408605}; Flags: Fragment;+++[F8VZL7_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000447332}; Flags: Fragment;+++[H7C4B6_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000416569}; Flags: Fragment;+++[J3KS24_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000462274}; Flags: Fragment;+++[J3QKX0_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000463272}; Flags: Fragment;+++[J3QQP5_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000463827}; Flags: Fragment;+++[J3QSE8_HUMAN|Unreviewed]SubName: Full=Fanconi anemia group J protein {ECO:0000313|Ensembl:ENSP00000464654};+++[M0QZP0_HUMAN|Unreviewed]SubName: Full=Transcription regulator protein BACH1 {ECO:0000313|Ensembl:ENSP00000470673}; Flags: Fragment;+++[Q9BXM4_HUMAN|Unreviewed]SubName: Full=Transcription factor BACH1t {ECO:0000313|EMBL:AAK08197.1}; Flags: Fragment;"]
[84061,"'MAGT1'",1330,1169,1156,1218.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005886///plasma membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0035577///azurophil granule membrane+++GO:0005887///integral component of plasma membrane","GO:0015095///magnesium ion transmembrane transporter activity+++GO:0004579///dolichyl-diphosphooligosaccharide-protein glycotransferase activity","GO:0006487///protein N-linked glycosylation+++GO:1903830///magnesium ion transmembrane transport+++GO:0050890///cognition+++GO:0015693///magnesium ion transport+++GO:0043312///neutrophil degranulation+++GO:0006486///protein glycosylation+++GO:0055085///transmembrane transport+++GO:0018279///protein N-linked glycosylation via asparagine","magnesium transporter 1","[MAGT1_HUMAN|Reviewed]RecName: Full=Magnesium transporter protein 1; Short=MagT1; AltName: Full=Implantation-associated protein; Short=IAP; Flags: Precursor;+++[A0A087WU53_HUMAN|Unreviewed]SubName: Full=Magnesium transporter protein 1 {ECO:0000313|Ensembl:ENSP00000478379};"]
[8408,"'ULK1'",4845,3917,4348,4370,"04152///AMPK signaling pathway+++04150///mTOR signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0097629///extrinsic component of omegasome membrane+++GO:0097632///extrinsic component of phagophore assembly site membrane+++GO:0097635///extrinsic component of autophagosome membrane+++GO:0005829///cytosol+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005741///mitochondrial outer membrane+++GO:0005737///cytoplasm+++GO:0034045///phagophore assembly site membrane+++GO:0005776///autophagosome+++GO:0016020///membrane+++GO:0055037///recycling endosome+++GO:0030424///axon+++GO:0000407///phagophore assembly site","GO:0042802///identical protein binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0051020///GTPase binding+++GO:0044877///protein-containing complex binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0016740///transferase activity","GO:0016241///regulation of macroautophagy+++GO:0007409///axonogenesis+++GO:0031669///cellular response to nutrient levels+++GO:0008104///protein localization+++GO:0016236///macroautophagy+++GO:0007165///signal transduction+++GO:0042594///response to starvation+++GO:0006914///autophagy+++GO:0010506///regulation of autophagy+++GO:0046777///protein autophosphorylation+++GO:2000786///positive regulation of autophagosome assembly+++GO:0006468///protein phosphorylation+++GO:0000045///autophagosome assembly+++GO:0031175///neuron projection development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0031102///neuron projection regeneration+++GO:0031333///negative regulation of protein complex assembly+++GO:0016310///phosphorylation+++GO:0048675///axon extension","unc-51 like autophagy activating kinase 1","[ULK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase ULK1; EC=2.7.11.1; AltName: Full=Autophagy-related protein 1 homolog; Short=ATG1; Short=hATG1; AltName: Full=Unc-51-like kinase 1;"]
[8412,"'BCAR3'",1066,1051,885,1000.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005938///cell cortex+++GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005634///nucleus","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042493///response to drug+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0007264///small GTPase mediated signal transduction","BCAR3, NSP family adaptor protein","[BCAR3_HUMAN|Reviewed]RecName: Full=Breast cancer anti-estrogen resistance protein 3; AltName: Full=Novel SH2-containing protein 2; AltName: Full=SH2 domain-containing protein 3B;+++[B3KNL6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14879 fis, clone PLACE1003353, highly similar to Breast cancer anti-estrogen resistance protein 3 {ECO:0000313|EMBL:BAG51378.1};+++[B3KP06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30880 fis, clone FEBRA2004767, highly similar to Breast cancer anti-estrogen resistance protein 3 {ECO:0000313|EMBL:BAG51518.1};"]
[84152,"'PPP1R1B'",54,22,17,31,"05034///Alcoholism+++05030///Cocaine addiction+++04728///Dopaminergic synapse+++04024///cAMP signaling pathway+++05031///Amphetamine addiction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0044326///dendritic spine neck+++GO:0098794///postsynapse+++GO:0044327///dendritic spine head+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0004862///cAMP-dependent protein kinase inhibitor activity+++GO:0031748///D1 dopamine receptor binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0031749///D2 dopamine receptor binding+++GO:0005515///protein binding+++GO:0031752///D5 dopamine receptor binding+++GO:0031750///D3 dopamine receptor binding+++GO:0031751///D4 dopamine receptor binding+++GO:0019888///protein phosphatase regulator activity+++GO:0004860///protein kinase inhibitor activity","GO:0035094///response to nicotine+++GO:0043278///response to morphine+++GO:0042220///response to cocaine+++GO:0001975///response to amphetamine+++GO:0006469///negative regulation of protein kinase activity+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0007621///negative regulation of female receptivity+++GO:0007626///locomotory behavior+++GO:0007165///signal transduction+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0006351///transcription, DNA-templated+++GO:0008542///visual learning+++GO:0035556///intracellular signal transduction+++GO:0048148///behavioral response to cocaine+++GO:0007613///memory","protein phosphatase 1 regulatory inhibitor subunit 1B","[PPR1B_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1 regulatory subunit 1B; AltName: Full=DARPP-32; AltName: Full=Dopamine- and cAMP-regulated neuronal phosphoprotein;+++[A0A024R1R3_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1, regulatory (Inhibitor) subunit 1B (Dopamine and cAMP regulated phosphoprotein, DARPP-32), isoform CRA_a {ECO:0000313|EMBL:EAW60581.1};+++[B3KVQ9_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1, regulatory (Inhibitor) subunit 1B (Dopamine and cAMP regulated phosphoprotein, DARPP-32), isoform CRA_b {ECO:0000313|EMBL:EAW60582.1}; SubName: Full=cDNA FLJ41117 fis, clone BRACE2006821, highly similar to Dopamine- and cAMP-regulated neuronalphospho protein {ECO:0000313|EMBL:BAG53871.1}; SubName: Full=cDNA FLJ45635 fis, clone COLON2001829, highly similar to Dopamine- and cAMP-regulated neuronal phosphoprotein {ECO:0000313|EMBL:BAG54520.1};+++[J3KSJ8_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1 regulatory subunit 1B {ECO:0000313|Ensembl:ENSP00000462522}; Flags: Fragment;+++[J3KT77_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1 regulatory subunit 1B {ECO:0000313|Ensembl:ENSP00000462841};"]
[84172,"'POLR1B'",263,265,247,258.333333333333,"01100///Metabolic pathways+++03020///RNA polymerase+++00230///Purine metabolism+++00240///Pyrimidine metabolism",null,"M00182///RNA polymerase I, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0035861///site of double-strand break+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000781///chromosome, telomeric region+++GO:0016604///nuclear body+++GO:0005736///RNA polymerase I complex+++GO:0005730///nucleolus+++GO:0005662///DNA replication factor A complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0016605///PML body","GO:0032549///ribonucleoside binding+++GO:0019903///protein phosphatase binding+++GO:0016779///nucleotidyltransferase activity+++GO:0019899///enzyme binding+++GO:0016740///transferase activity+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001054///RNA polymerase I activity+++GO:0003697///single-stranded DNA binding+++GO:0047485///protein N-terminus binding+++GO:0003684///damaged DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003690///double-stranded DNA binding+++GO:0031625///ubiquitin protein ligase binding","GO:0033683///nucleotide-excision repair, DNA incision+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0006260///DNA replication+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0036297///interstrand cross-link repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0017126///nucleologenesis+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0009303///rRNA transcription+++GO:0032201///telomere maintenance via semi-conservative replication+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0019985///translesion synthesis+++GO:0000722///telomere maintenance via recombination+++GO:0007004///telomere maintenance via telomerase+++GO:0070987///error-free translesion synthesis+++GO:0006281///DNA repair+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0006351///transcription, DNA-templated+++GO:0030491///heteroduplex formation+++GO:0006289///nucleotide-excision repair+++GO:0042276///error-prone translesion synthesis+++GO:2000001///regulation of DNA damage checkpoint+++GO:0051096///positive regulation of helicase activity+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0006312///mitotic recombination+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006298///mismatch repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006268///DNA unwinding involved in DNA replication+++GO:1900034///regulation of cellular response to heat+++GO:0006284///base-excision repair+++GO:0006310///DNA recombination+++GO:0006265///DNA topological change+++GO:0034502///protein localization to chromosome+++GO:0000723///telomere maintenance+++GO:0007566///embryo implantation","RNA polymerase I subunit B","[RPA2_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase I subunit RPA2; Short=RNA polymerase I subunit 2; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase I 135 kDa polypeptide; Short=RPA135;+++[B7Z1W6_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031}; EC=2.7.7.6 {ECO:0000256|RuleBase:RU363031};+++[C9JJG2_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000415754}; Flags: Fragment;+++[C9JS83_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000388577}; Flags: Fragment;+++[F8WAK7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000334589};+++[F8WBB9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000390973};+++[F8WCS3_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000390274};+++[F8WDS4_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000403094};+++[H7C0D9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000394408}; Flags: Fragment;+++[Q4QRK8_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH96748.1}; Flags: Fragment;+++[Q5TEJ0_HUMAN|Unreviewed]SubName: Full=Replication protein A 32 kDa subunit {ECO:0000313|Ensembl:ENSP00000413541}; Flags: Fragment;+++[Q5TEJ7_HUMAN|Unreviewed]SubName: Full=Replication protein A 32 kDa subunit {ECO:0000313|Ensembl:ENSP00000387649}; Flags: Fragment;+++[Q6DKI9_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH73857.1}; Flags: Fragment;+++[Q9BSR4_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH04882.4}; Flags: Fragment;"]
[84217,"'ZMYND12'",22,13,17,17.3333333333333,"04140///Autophagy - animal+++00770///Pantothenate and CoA biosynthesis+++01100///Metabolic pathways+++04137///Mitophagy - animal",null,"M00120///Coenzyme A biosynthesis, pantothenate => CoA","R04230///(R)-4'-phosphopantothenate:L-cysteine ligase (ATP-utilizing) ATP + D-4'-Phosphopantothenate + L-Cysteine <=> AMP + Diphosphate + (R)-4'-Phosphopantothenoyl-L-cysteine","GO:0005622///intracellular","GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","zinc finger MYND-type containing 12","[ZMY12_HUMAN|Reviewed]RecName: Full=Zinc finger MYND domain-containing protein 12;+++[A0A087WUN3_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000478789};+++[A0A087WZE7_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 12 {ECO:0000313|Ensembl:ENSP00000482602};+++[B4DX70_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58334, highly similar to Zinc finger MYND domain-containing protein 12 {ECO:0000313|EMBL:BAG63282.1};"]
[84233,"'TMEM126A'",83,72,115,90,null,"H01020///Optic atrophy (OPA)",null,null,"GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0021554///optic nerve development","transmembrane protein 126A","[T126A_HUMAN|Reviewed]RecName: Full=Transmembrane protein 126A;+++[E9PI90_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 126A {ECO:0000313|Ensembl:ENSP00000436723};+++[E9PIH8_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 126A {ECO:0000313|Ensembl:ENSP00000431993};"]
[84261,"'FBXW9'",287,234,266,262.333333333333,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0070545///PeBoW complex+++GO:0005829///cytosol","GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0000209///protein polyubiquitination+++GO:0043687///post-translational protein modification","F-box and WD repeat domain containing 9","[FBXW9_HUMAN|Reviewed]RecName: Full=F-box/WD repeat-containing protein 9; AltName: Full=F-box and WD-40 domain-containing protein 9;+++[A0A024R7F0_HUMAN|Unreviewed]SubName: Full=F-box and WD-40 domain protein 9, isoform CRA_a {ECO:0000313|EMBL:EAW84297.1};+++[K7EL01_HUMAN|Unreviewed]SubName: Full=F-box/WD repeat-containing protein 9 {ECO:0000313|Ensembl:ENSP00000465854};"]
[84271,"'POLDIP3'",1013,1017,984,1004.66666666667,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005623///cell+++GO:0016607///nuclear speck+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005634///nucleus+++GO:0000346///transcription export complex","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0045727///positive regulation of translation+++GO:0031124///mRNA 3'-end processing+++GO:0051028///mRNA transport+++GO:0006417///regulation of translation+++GO:0016973///poly(A)+ mRNA export from nucleus","DNA polymerase delta interacting protein 3","[PDIP3_HUMAN|Reviewed]RecName: Full=Polymerase delta-interacting protein 3; AltName: Full=46 kDa DNA polymerase delta interaction protein; Short=p46; AltName: Full=S6K1 Aly/REF-like target; Short=SKAR;+++[B4E0L0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54030, highly similar to Polymerase delta-interacting protein 3 {ECO:0000313|EMBL:BAG64472.1};+++[F6VRR5_HUMAN|Unreviewed]SubName: Full=Polymerase delta-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000397927};+++[F8WCX5_HUMAN|Unreviewed]SubName: Full=Polymerase delta-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000415234};+++[F8WEE2_HUMAN|Unreviewed]SubName: Full=Polymerase delta-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000408046};+++[Q659C6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp434G0310 {ECO:0000313|EMBL:CAH56378.1}; Flags: Fragment;+++[Q6R954_HUMAN|Unreviewed]SubName: Full=Polymerase delta interacting protein 46 {ECO:0000313|EMBL:AAR91612.1}; SubName: Full=Polymerase delta-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000343060};+++[Q8WUT1_HUMAN|Unreviewed]SubName: Full=POLDIP3 protein {ECO:0000313|EMBL:AAH19643.1}; SubName: Full=Polymerase delta-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000482500};+++[Q96DI9_HUMAN|Unreviewed]SubName: Full=POLDIP3 protein {ECO:0000313|EMBL:AAH01488.2}; Flags: Fragment;"]
[84277,"'DNAJC30'",388,436,512,445.333333333333,null,"H01439///Williams-Beuren syndrome",null,null,"GO:0005743///mitochondrial inner membrane","GO:0005515///protein binding","GO:1905706///regulation of mitochondrial ATP synthesis coupled proton transport+++GO:0007420///brain development","DnaJ heat shock protein family (Hsp40) member C30","[DJC30_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily C member 30; AltName: Full=Williams-Beuren syndrome chromosomal region 18 protein;+++[B3KSU4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36986 fis, clone BRACE2006598, highly similar to Williams-Beuren syndrome chromosome region 18 protein {ECO:0000313|EMBL:BAG52856.1};"]
[84303,"'CHCHD6'",274,210,297,260.333333333333,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0061617///MICOS complex","GO:0005515///protein binding","GO:0042407///cristae formation+++GO:0006974///cellular response to DNA damage stimulus","coiled-coil-helix-coiled-coil-helix domain containing 6","[MIC25_HUMAN|Reviewed]RecName: Full=MICOS complex subunit MIC25; AltName: Full=Coiled-coil-helix cristae morphology protein 1; AltName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 6;+++[H0Y922_HUMAN|Unreviewed]RecName: Full=MICOS complex subunit {ECO:0000256|RuleBase:RU363001}; Flags: Fragment;+++[J3QTA6_HUMAN|Unreviewed]RecName: Full=MICOS complex subunit {ECO:0000256|RuleBase:RU363001};+++[J3QTB2_HUMAN|Unreviewed]RecName: Full=MICOS complex subunit {ECO:0000256|RuleBase:RU363001};"]
[84310,"'C7orf50'",1542,1651,2021,1738,"04915///Estrogen signaling pathway+++04137///Mitophagy - animal+++04140///Autophagy - animal+++01522///Endocrine resistance",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0030425///dendrite+++GO:0005769///early endosome+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0005622///intracellular+++GO:0005788///endoplasmic reticulum lumen+++GO:0005783///endoplasmic reticulum+++GO:0043679///axon terminus+++GO:0055037///recycling endosome+++GO:0043198///dendritic shaft+++GO:0048471///perinuclear region of cytoplasm+++GO:0030424///axon+++GO:0044327///dendritic spine head+++GO:0005737///cytoplasm+++GO:0048786///presynaptic active zone+++GO:0045095///keratin filament+++GO:0031966///mitochondrial membrane+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0042734///presynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0032591///dendritic spine membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0043410///positive regulation of MAPK cascade+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0071356///cellular response to tumor necrosis factor+++GO:0010628///positive regulation of gene expression+++GO:0002695///negative regulation of leukocyte activation+++GO:0071392///cellular response to estradiol stimulus+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0010629///negative regulation of gene expression+++GO:0030264///nuclear fragmentation involved in apoptotic nuclear change+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0006954///inflammatory response+++GO:0032962///positive regulation of inositol trisphosphate biosynthetic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0050769///positive regulation of neurogenesis+++GO:0071333///cellular response to glucose stimulus+++GO:0030335///positive regulation of cell migration+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007049///cell cycle+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0050728///negative regulation of inflammatory response+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0045087///innate immune response+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:2000724///positive regulation of cardiac vascular smooth muscle cell differentiation+++GO:0071389///cellular response to mineralocorticoid stimulus+++GO:0051055///negative regulation of lipid biosynthetic process+++GO:0006805///xenobiotic metabolic process+++GO:0030263///apoptotic chromosome condensation+++GO:0051053///negative regulation of DNA metabolic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0008285///negative regulation of cell proliferation+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0071157///negative regulation of cell cycle arrest+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:2000353///positive regulation of endothelial cell apoptotic process+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0019228///neuronal action potential+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0097755///positive regulation of blood vessel diameter+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0008284///positive regulation of cell proliferation+++GO:0019373///epoxygenase P450 pathway+++GO:0010948///negative regulation of cell cycle process+++GO:0045599///negative regulation of fat cell differentiation+++GO:0032024///positive regulation of insulin secretion+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0043390///aflatoxin B1 metabolic process+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0045745///positive regulation of G protein-coupled receptor signaling pathway","chromosome 7 open reading frame 50","[CG050_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C7orf50;+++[C9JQV0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C7orf50 {ECO:0000313|Ensembl:ENSP00000420130}; Flags: Fragment;+++[H7C0T1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C7orf50 {ECO:0000313|Ensembl:ENSP00000396542}; Flags: Fragment;+++[H7C2R9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C7orf50 {ECO:0000313|Ensembl:ENSP00000407380}; Flags: Fragment;+++[Q8TAS9_HUMAN|Unreviewed]SubName: Full=C7orf50 protein {ECO:0000313|EMBL:AAH25971.1}; SubName: Full=HCG1993407 {ECO:0000313|EMBL:EAW87190.1}; Flags: Fragment;"]
[84337,"'ELOF1'",728,720,847,765,{"$nulls":4},"GO:0005634///nucleus+++GO:0008023///transcription elongation factor complex+++GO:0005654///nucleoplasm","GO:0043565///sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003746///translation elongation factor activity+++GO:0046872///metal ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding","GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0006414///translational elongation+++GO:0030154///cell differentiation+++GO:0050855///regulation of B cell receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001817///regulation of cytokine production","elongation factor 1 homolog","[ELOF1_HUMAN|Reviewed]RecName: Full=Transcription elongation factor 1 homolog;+++[A0A024R7E8_HUMAN|Unreviewed]RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};+++[A0A0D9SG85_HUMAN|Unreviewed]SubName: Full=ETS-related transcription factor Elf-1 {ECO:0000313|Ensembl:ENSP00000487240};+++[A0A0U1RRL5_HUMAN|Unreviewed]SubName: Full=ETS-related transcription factor Elf-1 {ECO:0000313|Ensembl:ENSP00000489586}; Flags: Fragment;+++[K7EL94_HUMAN|Unreviewed]SubName: Full=Transcription elongation factor 1 homolog {ECO:0000313|Ensembl:ENSP00000465973}; Flags: Fragment;+++[K7EMV4_HUMAN|Unreviewed]RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};+++[K7EN05_HUMAN|Unreviewed]RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};+++[K7EPC8_HUMAN|Unreviewed]RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};+++[K7EQ44_HUMAN|Unreviewed]RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};+++[L8E9U9_HUMAN|Unreviewed]SubName: Full=Alternative protein ELF1 {ECO:0000313|EMBL:CCQ43123.1};+++[Q5T9E7_HUMAN|Unreviewed]SubName: Full=ETS-related transcription factor Elf-1 {ECO:0000313|Ensembl:ENSP00000384135}; Flags: Fragment;"]
[84376,"'HOOK3'",455.34,416.27,326.89,399.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005623///cell+++GO:0034774///secretory granule lumen+++GO:0034451///centriolar satellite+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0070695///FHF complex+++GO:0005874///microtubule+++GO:0005813///centrosome+++GO:0000242///pericentriolar material+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005801///cis-Golgi network+++GO:0005829///cytosol+++GO:0030897///HOPS complex+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton","GO:0005524///ATP binding+++GO:0008865///fructokinase activity+++GO:0008017///microtubule binding+++GO:0045503///dynein light chain binding+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0004340///glucokinase activity+++GO:0034452///dynactin binding+++GO:0005515///protein binding+++GO:0005536///glucose binding+++GO:0004396///hexokinase activity+++GO:0016301///kinase activity+++GO:0045505///dynein intermediate chain binding+++GO:0003824///catalytic activity+++GO:0019158///mannokinase activity+++GO:0042802///identical protein binding+++GO:0016740///transferase activity+++GO:0051959///dynein light intermediate chain binding+++GO:0000166///nucleotide binding","GO:0022027///interkinetic nuclear migration+++GO:0006096///glycolytic process+++GO:0031122///cytoplasmic microtubule organization+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0061621///canonical glycolysis+++GO:0097150///neuronal stem cell population maintenance+++GO:0051156///glucose 6-phosphate metabolic process+++GO:0007032///endosome organization+++GO:0001678///cellular glucose homeostasis+++GO:0007040///lysosome organization+++GO:0008333///endosome to lysosome transport+++GO:0050768///negative regulation of neurogenesis+++GO:0015031///protein transport+++GO:0045022///early endosome to late endosome transport+++GO:0016310///phosphorylation+++GO:0034454///microtubule anchoring at centrosome+++GO:0071539///protein localization to centrosome+++GO:0043312///neutrophil degranulation+++GO:0046835///carbohydrate phosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0019318///hexose metabolic process+++GO:0051645///Golgi localization+++GO:0008152///metabolic process","hook microtubule tethering protein 3","[HOOK3_HUMAN|Reviewed]RecName: Full=Protein Hook homolog 3; Short=h-hook3; Short=hHK3;+++[H0Y8U9_HUMAN|Unreviewed]RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007}; EC=2.7.1.- {ECO:0000256|RuleBase:RU362007}; Flags: Fragment;+++[H0Y9N6_HUMAN|Unreviewed]RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007}; EC=2.7.1.- {ECO:0000256|RuleBase:RU362007}; Flags: Fragment;+++[H0YAG4_HUMAN|Unreviewed]SubName: Full=Hexokinase-3 {ECO:0000313|Ensembl:ENSP00000427000}; Flags: Fragment;+++[H0YDK4_HUMAN|Unreviewed]SubName: Full=Protein Hook homolog 3 {ECO:0000313|Ensembl:ENSP00000433813}; Flags: Fragment;+++[H0YDM4_HUMAN|Unreviewed]SubName: Full=Protein Hook homolog 3 {ECO:0000313|Ensembl:ENSP00000433953}; Flags: Fragment;+++[H0YE69_HUMAN|Unreviewed]SubName: Full=Protein Hook homolog 3 {ECO:0000313|Ensembl:ENSP00000435077}; Flags: Fragment;+++[Q16779_HUMAN|Unreviewed]SubName: Full=Hexokinase III {ECO:0000313|EMBL:AAB03512.1}; EC=2.7.1.1 {ECO:0000313|EMBL:AAB03512.1}; Flags: Fragment;"]
[84443,"'FRMPD3'",218,97,100,138.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0070821///tertiary granule membrane+++GO:0030667///secretory granule membrane+++GO:0005886///plasma membrane",null,"GO:0043312///neutrophil degranulation","FERM and PDZ domain containing 3","[FRPD3_HUMAN|Reviewed]RecName: Full=FERM and PDZ domain-containing protein 3;+++[A0A0A0MSP7_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000398668}; Flags: Fragment;"]
[8449,"'DHX16'",764,763,756,761,"03040///Spliceosome",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex","GO:0003724///RNA helicase activity+++GO:0003676///nucleic acid binding+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0016887///ATPase activity+++GO:0016787///hydrolase activity","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","DEAH-box helicase 16","[DHX16_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase #3; AltName: Full=DEAH-box protein 16;+++[A0A140T8Y5_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 {ECO:0000313|Ensembl:ENSP00000373070};+++[A0A140T947_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 {ECO:0000313|Ensembl:ENSP00000391789}; Flags: Fragment;+++[A0A140T9T4_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 {ECO:0000313|Ensembl:ENSP00000412716}; Flags: Fragment;+++[A0A1U9X7L7_HUMAN|Unreviewed]SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_b {ECO:0000313|EMBL:EAX03313.1}; SubName: Full=DHX16 {ECO:0000313|EMBL:AQY76785.2};+++[A2AB15_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 {ECO:0000313|Ensembl:ENSP00000399101}; Flags: Fragment;+++[B4DZ28_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53577, highly similar to pre-mRNA-splicing factor ATP-dependentRNA helicase DHX16 {ECO:0000313|EMBL:BAG63940.1};+++[Q5SQH4_HUMAN|Unreviewed]SubName: Full=DBP2 protein {ECO:0000313|EMBL:BAF31265.1}; SubName: Full=DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16 {ECO:0000313|EMBL:BAC54930.1}; SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_e {ECO:0000313|EMBL:EAX03316.1}; SubName: Full=cDNA, FLJ92560, highly similar to Homo sapiens DEAH (Asp-Glu-Ala-His) box polypeptide 16 (DHX16), mRNA {ECO:0000313|EMBL:BAG35195.1};+++[Q5SQH5_HUMAN|Unreviewed]SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_a {ECO:0000313|EMBL:EAX03312.1}; SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 {ECO:0000313|Ensembl:ENSP00000365620};+++[Q6PKC8_HUMAN|Unreviewed]SubName: Full=DHX16 protein {ECO:0000313|EMBL:AAH02789.1}; Flags: Fragment;"]
[84515,"'MCM8'",105,125.99,124,118.33,{"$nulls":4},"GO:0097362///MCM8-MCM9 complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005694///chromosome","GO:0032406///MutLbeta complex binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003682///chromatin binding+++GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0032407///MutSalpha complex binding+++GO:0005524///ATP binding+++GO:0004386///helicase activity+++GO:0032408///MutSbeta complex binding","GO:0007292///female gamete generation+++GO:0006270///DNA replication initiation+++GO:0048232///male gamete generation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0050821///protein stabilization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0036298///recombinational interstrand cross-link repair+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0071168///protein localization to chromatin+++GO:0000724///double-strand break repair via homologous recombination","minichromosome maintenance 8 homologous recombination repair factor","[MCM8_HUMAN|Reviewed]RecName: Full=DNA helicase MCM8; EC=3.6.4.12 {ECO:0000305|PubMed:26215093}; AltName: Full=Minichromosome maintenance 8;+++[A0A0S2Z5Q9_HUMAN|Unreviewed]SubName: Full=Minichromosome maintenance complex component 8 isoform 1 {ECO:0000313|EMBL:ALQ34261.1}; Flags: Fragment;+++[A0A0S2Z5R6_HUMAN|Unreviewed]SubName: Full=Minichromosome maintenance complex component 8 isoform 2 {ECO:0000313|EMBL:ALQ34262.1};+++[A0A0S2Z618_HUMAN|Unreviewed]SubName: Full=Minichromosome maintenance complex component 8 isoform 3 {ECO:0000313|EMBL:ALQ34263.1}; Flags: Fragment;+++[B4DN82_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57869, highly similar to DNA replication licensing factor MCM8 {ECO:0000313|EMBL:BAG60144.1};"]
[84548,"'TMEM185A'",338,270,303,303.666666666667,{"$nulls":4},"GO:0030425///dendrite+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0042995///cell projection","GO:0005515///protein binding","GO:0006351///transcription, DNA-templated","transmembrane protein 185A","[T185A_HUMAN|Reviewed]RecName: Full=Transmembrane protein 185A; AltName: Full=Protein FAM11A;+++[A0A087X081_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000483167};+++[B3KY49_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 11, member A, isoform CRA_a {ECO:0000313|EMBL:EAW99367.1}; SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000482375}; SubName: Full=cDNA FLJ46855 fis, clone UTERU3010029, highly similar to Protein FAM11A {ECO:0000313|EMBL:BAG54711.1};+++[B7Z4G6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000483235}; SubName: Full=cDNA FLJ52946, highly similar to Protein FAM11A {ECO:0000313|EMBL:BAH12552.1};+++[E5RFI9_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000428852};+++[E5RGV1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000428659}; Flags: Fragment;+++[E7EMM1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000427766};+++[H0YAP3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000427814}; Flags: Fragment;+++[H0YBJ6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 185A {ECO:0000313|Ensembl:ENSP00000429625}; Flags: Fragment;+++[Q3MI96_HUMAN|Unreviewed]SubName: Full=TMEM185A protein {ECO:0000313|EMBL:AAI03821.1}; Flags: Fragment;+++[Q8TCB3_HUMAN|Unreviewed]SubName: Full=TMEM185A protein {ECO:0000313|EMBL:AAH22405.1};"]
[8460,"'TPST1'",242,250,248,246.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane","GO:0008476///protein-tyrosine sulfotransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity","GO:0006478///peptidyl-tyrosine sulfation+++GO:0006954///inflammatory response+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process","tyrosylprotein sulfotransferase 1","[TPST1_HUMAN|Reviewed]RecName: Full=Protein-tyrosine sulfotransferase 1; EC=2.8.2.20 {ECO:0000269|PubMed:28821720, ECO:0000269|PubMed:9501187, ECO:0000269|PubMed:9733778}; AltName: Full=Tyrosylprotein sulfotransferase 1; Short=TPST-1;+++[A0A024RDK9_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018};+++[C9J3I4_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018}; Flags: Fragment;+++[C9K0F3_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018}; Flags: Fragment;+++[Q75M96_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018}; Flags: Fragment;+++[Q75ML6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TPST1 {ECO:0000313|EMBL:AAS02012.1}; Flags: Fragment;"]
[84640,"'USP38'",831,726,570,709,{"$nulls":5},"GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity","GO:0016579///protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006508///proteolysis","ubiquitin specific peptidase 38","[UBP38_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 38; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 38; AltName: Full=HP43.8KD; AltName: Full=Ubiquitin thioesterase 38; AltName: Full=Ubiquitin-specific-processing protease 38;+++[B3KSB9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ35970 fis, clone TESTI2013231, highly similar to Ubiquitin carboxyl-terminal hydrolase 38 (EC3.1.2.15) {ECO:0000313|EMBL:BAG52681.1};+++[H0Y9H5_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 38 {ECO:0000313|Ensembl:ENSP00000424158}; Flags: Fragment;"]
[84669,"'USP32'",1214.82,1011.36,868.51,1031.56333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005768///endosome","GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0002039///p53 binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0044325///ion channel binding+++GO:0003723///RNA binding","GO:0006914///autophagy+++GO:0071347///cellular response to interleukin-1+++GO:0019985///translesion synthesis+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016579///protein deubiquitination+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0006508///proteolysis+++GO:0010506///regulation of autophagy+++GO:0006281///DNA repair","ubiquitin specific peptidase 32","[UBP32_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 32; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 32; AltName: Full=Renal carcinoma antigen NY-REN-60; AltName: Full=Ubiquitin thioesterase 32; AltName: Full=Ubiquitin-specific-processing protease 32; Flags: Precursor;+++[H3BNA1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454751}; Flags: Fragment;+++[H3BNL0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454902};+++[H3BNP1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454943};+++[H3BNS8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454987}; Flags: Fragment;+++[H3BQC6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000455712}; Flags: Fragment;+++[H3BQP1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000455865}; Flags: Fragment;+++[H3BVF1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000458089}; Flags: Fragment;+++[J3KT19_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000462762}; Flags: Fragment;+++[K7EII4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000464762}; Flags: Fragment;+++[K7EKK3_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000465659}; Flags: Fragment;+++[K7EKZ1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000465844}; Flags: Fragment;+++[K7EL53_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000465922}; Flags: Fragment;+++[K7EN13_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000466740}; Flags: Fragment;+++[K7ENU6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000467098}; Flags: Fragment;+++[K7EPL4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000467435}; Flags: Fragment;+++[K7EQL6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000467885};+++[Q4VC15_HUMAN|Unreviewed]SubName: Full=USP32 protein {ECO:0000313|EMBL:AAH94680.1}; Flags: Fragment;+++[Q68D90_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000445589};+++[Q6IRT0_HUMAN|Unreviewed]SubName: Full=USP32 protein {ECO:0000313|EMBL:AAH70497.1}; Flags: Fragment;+++[Q6P2I0_HUMAN|Unreviewed]SubName: Full=USP10 protein {ECO:0000313|EMBL:AAH64516.1}; Flags: Fragment;"]
[8470,"'SORBS2'",7732,6753,5042,6509,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005654///nucleoplasm+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0030018///Z disc+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm","GO:0005200///structural constituent of cytoskeleton+++GO:0003723///RNA binding+++GO:0008307///structural constituent of muscle+++GO:0008093///cytoskeletal adaptor activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0007015///actin filament organization+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0008150///biological_process+++GO:0007219///Notch signaling pathway","sorbin and SH3 domain containing 2","[SRBS2_HUMAN|Reviewed]RecName: Full=Sorbin and SH3 domain-containing protein 2; AltName: Full=Arg-binding protein 2; Short=ArgBP2; AltName: Full=Arg/Abl-interacting protein 2; AltName: Full=Sorbin;+++[A0A1D5RMN3_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000377158}; Flags: Fragment;+++[B7Z3D7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55213, highly similar to Rattus norvegicus Arg/Abl-interacting protein ArgBP2 (Argbp2), mRNA {ECO:0000313|EMBL:BAH12173.1};+++[B7Z997_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54581, highly similar to Homo sapiens sorbin and SH3 domain containing 2 (SORBS2), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH14233.1};+++[C9IZ89_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000399048}; Flags: Fragment;+++[C9IZT7_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000412447}; Flags: Fragment;+++[C9J348_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000405349}; Flags: Fragment;+++[C9J372_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000405314}; Flags: Fragment;+++[C9J3W4_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000410483}; Flags: Fragment;+++[C9J4K2_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000398335}; Flags: Fragment;+++[C9J4Z9_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000410233}; Flags: Fragment;+++[C9J620_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000405092}; Flags: Fragment;+++[C9J7Q5_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000397664}; Flags: Fragment;+++[C9J8E3_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000410967}; Flags: Fragment;+++[C9J9D3_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000405646}; Flags: Fragment;+++[C9JBB0_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000405432}; Flags: Fragment;+++[C9JBR8_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415680}; Flags: Fragment;+++[C9JC90_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415637}; Flags: Fragment;+++[C9JDX2_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000403417}; Flags: Fragment;+++[C9JEA9_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000396183}; Flags: Fragment;+++[C9JFS9_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000416464}; Flags: Fragment;+++[C9JG84_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000404430}; Flags: Fragment;+++[C9JI79_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000390162}; Flags: Fragment;+++[C9JL62_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000408909}; Flags: Fragment;+++[C9JLD6_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000389829}; Flags: Fragment;+++[C9JM25_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000402328}; Flags: Fragment;+++[C9JN77_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000408504}; Flags: Fragment;+++[C9JWC3_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393258}; Flags: Fragment;+++[C9JZ60_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000407006}; Flags: Fragment;+++[H7BXR3_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000321983}; Flags: Fragment;+++[H7BZK1_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000389995}; Flags: Fragment;+++[H7BZX1_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000391940}; Flags: Fragment;+++[H7C1R7_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000401818}; Flags: Fragment;"]
[84727,"'SPSB2'",126,157,125,136,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex","GO:1990756///protein binding, bridging involved in substrate recognition for ubiquitination+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0003674///molecular_function","GO:0035556///intracellular signal transduction+++GO:0008150///biological_process+++GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","splA/ryanodine receptor domain and SOCS box containing 2","[SPSB2_HUMAN|Reviewed]RecName: Full=SPRY domain-containing SOCS box protein 2; Short=SSB-2; AltName: Full=Gene-rich cluster protein C9;+++[E5RIC2_HUMAN|Unreviewed]SubName: Full=SPRY domain-containing SOCS box protein 2 {ECO:0000313|Ensembl:ENSP00000428458}; Flags: Fragment;"]
[84734,"'FAM167B'",0,5,7,4,{"$nulls":7},"family with sequence similarity 167 member B","[F167B_HUMAN|Reviewed]RecName: Full=Protein FAM167B;"]
[8482,"'SEMA7A'",65,53,84,67.3333333333333,"04360///Axon guidance",{"$nulls":3},"GO:0031225///anchored component of membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane","GO:0038191///neuropilin binding+++GO:0005515///protein binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding+++GO:0005178///integrin binding","GO:0001649///osteoblast differentiation+++GO:0030335///positive regulation of cell migration+++GO:0021988///olfactory lobe development+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050727///regulation of inflammatory response+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0031175///neuron projection development+++GO:0007229///integrin-mediated signaling pathway+++GO:0007399///nervous system development+++GO:0007275///multicellular organism development+++GO:0045773///positive regulation of axon extension+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0030154///cell differentiation+++GO:0006955///immune response+++GO:0048675///axon extension+++GO:0001755///neural crest cell migration+++GO:0006954///inflammatory response+++GO:0050919///negative chemotaxis+++GO:0060907///positive regulation of macrophage cytokine production","semaphorin 7A (John Milton Hagen blood group)","[SEM7A_HUMAN|Reviewed]RecName: Full=Semaphorin-7A; AltName: Full=CDw108; AltName: Full=JMH blood group antigen; AltName: Full=John-Milton-Hargen human blood group Ag; AltName: Full=Semaphorin-K1; Short=Sema K1; AltName: Full=Semaphorin-L; Short=Sema L; AltName: CD_antigen=CD108; Flags: Precursor;+++[B3KMH6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ11033 fis, clone PLACE1004203, highly similar to Semaphorin-7A {ECO:0000313|EMBL:BAG50988.1};+++[F5GYX3_HUMAN|Unreviewed]SubName: Full=Semaphorin-7A {ECO:0000313|Ensembl:ENSP00000441493};"]
[84823,"'LMNB2'",792,814,805,803.666666666667,"04210///Apoptosis+++04214///Apoptosis - fly","H01230///Adult-onset autosomal dominant leukodystrophy (ADLD)+++H00420///Familial partial lipodystrophy (FPL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,null,"GO:0005638///lamin filament+++GO:0005637///nuclear inner membrane+++GO:0043256///laminin complex+++GO:0005576///extracellular region+++GO:0043083///synaptic cleft+++GO:0005608///laminin-3 complex+++GO:0045202///synapse+++GO:0062023///collagen-containing extracellular matrix+++GO:0043260///laminin-11 complex+++GO:0005635///nuclear envelope+++GO:0031594///neuromuscular junction+++GO:0005882///intermediate filament+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0070062///extracellular exosome+++GO:0005604///basement membrane+++GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0005198///structural molecule activity+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding","GO:0031175///neuron projection development+++GO:0007411///axon guidance+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0044267///cellular protein metabolic process+++GO:0014002///astrocyte development+++GO:0007155///cell adhesion+++GO:0072274///metanephric glomerular basement membrane development+++GO:0007601///visual perception+++GO:0072249///metanephric glomerular visceral epithelial cell development+++GO:0048677///axon extension involved in regeneration+++GO:0060041///retina development in camera-type eye+++GO:0030198///extracellular matrix organization+++GO:0007528///neuromuscular junction development+++GO:0014044///Schwann cell development+++GO:0043687///post-translational protein modification+++GO:0050808///synapse organization+++GO:0008150///biological_process","lamin B2","[LMNB2_HUMAN|Reviewed]RecName: Full=Lamin-B2; Flags: Precursor;+++[A0A0A7M1X5_HUMAN|Unreviewed]SubName: Full=Lamin B2, isoform CRA_b {ECO:0000313|EMBL:EAW69379.1}; SubName: Full=Lamin B3 {ECO:0000313|EMBL:AIZ72720.1};+++[F5H520_HUMAN|Unreviewed]SubName: Full=Laminin subunit beta-2 {ECO:0000313|Ensembl:ENSP00000444751}; Flags: Fragment;"]
[84866,"'TMEM25'",865,1081,1059,1001.66666666667,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005576///extracellular region","GO:0005515///protein binding","GO:0050821///protein stabilization+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0060271///cilium assembly+++GO:0007224///smoothened signaling pathway+++GO:0042073///intraciliary transport","transmembrane protein 25","[TMM25_HUMAN|Reviewed]RecName: Full=Transmembrane protein 25; Flags: Precursor;+++[A0A024R3G8_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25, isoform CRA_b {ECO:0000313|EMBL:EAW67390.1};+++[B7Z1M8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57262, highly similar to Transmembrane protein 25 {ECO:0000313|EMBL:BAH11564.1};+++[E9PI73_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000436746}; Flags: Fragment;+++[E9PID6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000432062};+++[E9PIE6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000432040}; Flags: Fragment;+++[E9PIR4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000433938}; Flags: Fragment;+++[E9PIT4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000433906}; Flags: Fragment;+++[E9PK43_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000431663};+++[E9PK88_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000435446}; Flags: Fragment;+++[E9PKP3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000431548};+++[H0YC87_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000431145}; Flags: Fragment;+++[H0YD63_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 25 {ECO:0000313|Ensembl:ENSP00000433059}; Flags: Fragment;"]
[84888,"'SPPL2A'",605.19,469.72,498.49,524.466666666667,{"$nulls":4},"GO:0032040///small-subunit processome+++GO:0005770///late endosome+++GO:0030660///Golgi-associated vesicle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0034457///Mpp10 complex+++GO:0016020///membrane+++GO:0005840///ribosome+++GO:0071458///integral component of cytoplasmic side of endoplasmic reticulum membrane+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0005730///nucleolus+++GO:0031902///late endosome membrane+++GO:0005768///endosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0030684///preribosome+++GO:0070062///extracellular exosome+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane","GO:0042803///protein homodimerization activity+++GO:0004190///aspartic-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0019843///rRNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0042500///aspartic endopeptidase activity, intramembrane cleaving+++GO:0030515///snoRNA binding+++GO:0016787///hydrolase activity","GO:0031293///membrane protein intracellular domain proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0033619///membrane protein proteolysis+++GO:0050776///regulation of immune response+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing+++GO:0006508///proteolysis","signal peptide peptidase like 2A","[SPP2A_HUMAN|Reviewed]RecName: Full=Signal peptide peptidase-like 2A {ECO:0000303|PubMed:15385547, ECO:0000312|HGNC:HGNC:30227}; Short=SPP-like 2A {ECO:0000303|PubMed:15385547}; Short=SPPL2a {ECO:0000303|PubMed:15385547}; EC=3.4.23.-; AltName: Full=Intramembrane protease 3 {ECO:0000303|PubMed:12139484}; Short=IMP-3 {ECO:0000303|PubMed:12139484}; AltName: Full=Presenilin-like protein 2; Flags: Precursor;+++[H0YNA2_HUMAN|Unreviewed]SubName: Full=Signal peptide peptidase-like 2A {ECO:0000313|Ensembl:ENSP00000453927}; Flags: Fragment;+++[H0YNA7_HUMAN|Unreviewed]SubName: Full=Signal peptide peptidase-like 2A {ECO:0000313|Ensembl:ENSP00000453932}; Flags: Fragment;"]
[84908,"'FAM136A'",383,312,361,352,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"family with sequence similarity 136 member A","[F136A_HUMAN|Reviewed]RecName: Full=Protein FAM136A;+++[B0AZT6_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79526 {ECO:0000313|EMBL:BAF98768.1};+++[C9J2Y4_HUMAN|Unreviewed]SubName: Full=Protein FAM136A {ECO:0000313|Ensembl:ENSP00000391468};+++[C9JF51_HUMAN|Unreviewed]SubName: Full=Protein FAM136A {ECO:0000313|Ensembl:ENSP00000390840}; Flags: Fragment;+++[E7EQY1_HUMAN|Unreviewed]SubName: Full=Protein FAM136A {ECO:0000313|Ensembl:ENSP00000397269};"]
[84923,"'FAM104A'",352,378,361,363.666666666667,"04080///Neuroactive ligand-receptor interaction+++04024///cAMP signaling pathway+++04971///Gastric acid secretion","H00119///Congenital disorders of glycosylation (CDG) type II",null,null,"GO:0043005///neuron projection+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0017119///Golgi transport complex+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane","GO:0005515///protein binding","GO:0071385///cellular response to glucocorticoid stimulus+++GO:0030432///peristalsis+++GO:0006937///regulation of muscle contraction+++GO:0021549///cerebellum development+++GO:0030900///forebrain development+++GO:0042594///response to starvation+++GO:0008285///negative regulation of cell proliferation+++GO:0071392///cellular response to estradiol stimulus+++GO:0007030///Golgi organization+++GO:0007283///spermatogenesis+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0015031///protein transport+++GO:0006891///intra-Golgi vesicle-mediated transport","family with sequence similarity 104 member A","[F104A_HUMAN|Reviewed]RecName: Full=Protein FAM104A;+++[J3KSI9_HUMAN|Unreviewed]SubName: Full=Protein FAM104A {ECO:0000313|Ensembl:ENSP00000462507};+++[J3KT35_HUMAN|Unreviewed]SubName: Full=Protein FAM104A {ECO:0000313|Ensembl:ENSP00000462781};+++[J3KT52_HUMAN|Unreviewed]SubName: Full=Protein FAM104A {ECO:0000313|Ensembl:ENSP00000462806}; Flags: Fragment;+++[J3KT76_HUMAN|Unreviewed]SubName: Full=Protein FAM104A {ECO:0000313|Ensembl:ENSP00000462840};"]
[84942,"'WDR73'",196,200,215,203.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005819///spindle+++GO:0005737///cytoplasm+++GO:0032154///cleavage furrow","GO:0003674///molecular_function","GO:0043066///negative regulation of apoptotic process+++GO:0006997///nucleus organization+++GO:0031122///cytoplasmic microtubule organization","WD repeat domain 73","[WDR73_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 73;+++[B3KP50_HUMAN|Unreviewed]SubName: Full=WD repeat domain 73, isoform CRA_a {ECO:0000313|EMBL:EAX01945.1}; SubName: Full=cDNA FLJ31167 fis, clone KIDNE1000145, highly similar to Homo sapiens WD repeat domain 73 (WDR73), mRNA {ECO:0000313|EMBL:BAG51562.1};+++[H0YLH0_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 73 {ECO:0000313|Ensembl:ENSP00000453204}; Flags: Fragment;+++[H0YMT3_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 73 {ECO:0000313|Ensembl:ENSP00000453732}; Flags: Fragment;+++[H0YMX2_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 73 {ECO:0000313|Ensembl:ENSP00000453779}; Flags: Fragment;+++[Q5RKY8_HUMAN|Unreviewed]SubName: Full=WDR73 protein {ECO:0000313|EMBL:AAH50648.1}; Flags: Fragment;+++[Q6PJL8_HUMAN|Unreviewed]SubName: Full=WDR73 protein {ECO:0000313|EMBL:AAH14115.1}; Flags: Fragment;"]
[84958,"'SYTL1'",5,5,7,5.66666666666667,"05131///Shigellosis+++04810///Regulation of actin cytoskeleton+++04666///Fc gamma R-mediated phagocytosis+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++04520///Adherens junction+++05231///Choline metabolism in cancer",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0019897///extrinsic component of plasma membrane+++GO:0031528///microvillus membrane+++GO:0070382///exocytic vesicle+++GO:0005623///cell+++GO:0042470///melanosome+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0042043///neurexin family protein binding+++GO:0017137///Rab GTPase binding+++GO:0005515///protein binding","GO:0006887///exocytosis+++GO:0006886///intracellular protein transport","synaptotagmin like 1","[SYTL1_HUMAN|Reviewed]RecName: Full=Synaptotagmin-like protein 1; AltName: Full=Exophilin-7; AltName: Full=Protein JFC1;+++[A0A087X1N4_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-like protein 1 {ECO:0000313|Ensembl:ENSP00000484337};+++[Q5SSC6_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-like protein 1 {ECO:0000313|Ensembl:ENSP00000420110}; Flags: Fragment;"]
[84987,"'COX14'",268,274,323,288.333333333333,"04714///Thermogenesis","H01368///Cytochrome c oxidase (COX) deficiency","M00094///Ceramide biosynthesis+++M00099///Sphingosine biosynthesis","R01496///acyl-CoA:sphingosine N-acyltransferase Acyl-CoA + Sphingosine <=> CoA + N-Acylsphingosine+++R06517///acyl-CoA:sphingosine N-acyltransferase Acyl-CoA + Sphinganine <=> CoA + Dihydroceramide","GO:0031966///mitochondrial membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0003677///DNA binding+++GO:0050291///sphingosine N-acyltransferase activity","GO:0033617///mitochondrial respiratory chain complex IV assembly","cytochrome c oxidase assembly factor COX14","[COX14_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase assembly protein COX14;"]
[85013,"'TMEM128'",94,116,88,99.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005575///cellular_component+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0008150///biological_process","transmembrane protein 128","[TM128_HUMAN|Reviewed]RecName: Full=Transmembrane protein 128;+++[B7Z3K1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51973 {ECO:0000313|EMBL:BAH12237.1};"]
[8518,"'ELP1'",1464,1098,1068,1210,null,"H00265///Hereditary sensory and autonomic neuropathy (HSAN)+++H01987///Familial dysautonomia",null,null,"GO:0016021///integral component of membrane+++GO:0033588///Elongator holoenzyme complex+++GO:0005829///cytosol+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0008023///transcription elongation factor complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0008607///phosphorylase kinase regulator activity+++GO:0016301///kinase activity+++GO:0000993///RNA polymerase II complex binding","GO:0045859///regulation of protein kinase activity+++GO:0016310///phosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0002098///tRNA wobble uridine modification+++GO:0006955///immune response+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0030335///positive regulation of cell migration+++GO:0006468///protein phosphorylation+++GO:0065003///protein-containing complex assembly","elongator complex protein 1","[ELP1_HUMAN|Reviewed]RecName: Full=Elongator complex protein 1; Short=ELP1; AltName: Full=IkappaB kinase complex-associated protein; Short=IKK complex-associated protein; AltName: Full=p150;+++[B3KNB2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14161 fis, clone NT2RM2001803, highly similar to IkappaB kinase complex-associated protein {ECO:0000313|EMBL:BAG51274.1};+++[B4E3I9_HUMAN|Unreviewed]RecName: Full=Elongator complex protein 1 {ECO:0000256|PIRNR:PIRNR017233};+++[F5H2T0_HUMAN|Unreviewed]SubName: Full=Elongator complex protein 1 {ECO:0000313|Ensembl:ENSP00000439367};+++[H0YDF3_HUMAN|Unreviewed]SubName: Full=Elongator complex protein 1 {ECO:0000313|Ensembl:ENSP00000433514}; Flags: Fragment;+++[L8E918_HUMAN|Unreviewed]SubName: Full=Alternative protein IKBKAP {ECO:0000313|EMBL:CCQ43226.1};+++[Q4LE38_HUMAN|Unreviewed]SubName: Full=IKBKAP variant protein {ECO:0000313|EMBL:BAE06115.1}; Flags: Fragment;+++[Q8N516_HUMAN|Unreviewed]RecName: Full=Elongator complex protein 1 {ECO:0000256|PIRNR:PIRNR017233};"]
[85320,"'ABCC11'",46,30,25,33.6666666666667,"02010///ABC transporters",{"$nulls":3},"GO:0030659///cytoplasmic vesicle membrane+++GO:0005773///vacuole+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005774///vacuolar membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0015216///purine nucleotide transmembrane transporter activity+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0008514///organic anion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0015711///organic anion transport+++GO:0015865///purine nucleotide transport+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport","ATP binding cassette subfamily C member 11","[ABCCB_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family C member 11; AltName: Full=Multidrug resistance-associated protein 8;+++[A0A024R6Q6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 11, isoform CRA_a {ECO:0000313|EMBL:EAW82718.1};+++[A0A024R6R9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 11, isoform CRA_b {ECO:0000313|EMBL:EAW82722.1};+++[H3BRJ2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 11 {ECO:0000313|Ensembl:ENSP00000456268}; Flags: Fragment;"]
[85364,"'ZCCHC3'",436,361,339,378.666666666667,{"$nulls":5},"GO:0008270///zinc ion binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding",null,"zinc finger CCHC-type containing 3","[ZCHC3_HUMAN|Reviewed]RecName: Full=Zinc finger CCHC domain-containing protein 3;"]
[85416,"'ZIC5'",4,7,2,4.33333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation","Zic family member 5","[ZIC5_HUMAN|Reviewed]RecName: Full=Zinc finger protein ZIC 5; AltName: Full=Zinc finger protein of the cerebellum 5;"]
[85441,"'HELZ2'",1235,1625,2587,1815.66666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0004386///helicase activity+++GO:0035198///miRNA binding+++GO:0004540///ribonuclease activity+++GO:0000166///nucleotide binding+++GO:0004004///ATP-dependent RNA helicase activity","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0019216///regulation of lipid metabolic process+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription","helicase with zinc finger 2","[HELZ2_HUMAN|Reviewed]RecName: Full=Helicase with zinc finger domain 2; AltName: Full=ATP-dependent helicase PRIC285; AltName: Full=Helicase with zinc finger 2, transcriptional coactivator; AltName: Full=PPAR-alpha-interacting complex protein 285; AltName: Full=PPAR-gamma DNA-binding domain-interacting protein 1; Short=PDIP1; Short=PPAR-gamma DBD-interacting protein 1; AltName: Full=Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein; EC=3.6.4.-;+++[A7E2C9_HUMAN|Unreviewed]SubName: Full=Peroxisomal proliferator-activated receptor A interacting complex 285 {ECO:0000313|EMBL:AAI50284.1};+++[L0R8C7_HUMAN|Unreviewed]SubName: Full=Alternative protein PRIC285 {ECO:0000313|EMBL:CCO13796.1};+++[Q4VXQ0_HUMAN|Unreviewed]SubName: Full=PRIC285 protein {ECO:0000313|EMBL:AAI04975.1};"]
[85476,"'GFM1'",629,610,520,586.333333333333,null,"H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003746///translation elongation factor activity+++GO:0003723///RNA binding+++GO:0003924///GTPase activity","GO:0070125///mitochondrial translational elongation+++GO:0006412///translation+++GO:0006414///translational elongation","G elongation factor mitochondrial 1","[EFGM_HUMAN|Reviewed]RecName: Full=Elongation factor G, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03061}; Short=EF-Gmt {ECO:0000255|HAMAP-Rule:MF_03061}; AltName: Full=Elongation factor G 1, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03061}; Short=mEF-G 1 {ECO:0000255|HAMAP-Rule:MF_03061}; AltName: Full=Elongation factor G1 {ECO:0000255|HAMAP-Rule:MF_03061}; Short=hEFG1; Flags: Precursor;+++[A0A0S2Z5W5_HUMAN|Unreviewed]SubName: Full=G elongation factor mitochondrial 1 isoform 3 {ECO:0000313|EMBL:ALQ34275.1};+++[C9IZ01_HUMAN|Unreviewed]SubName: Full=Elongation factor G, mitochondrial {ECO:0000313|Ensembl:ENSP00000418755};+++[C9JA25_HUMAN|Unreviewed]SubName: Full=Elongation factor G, mitochondrial {ECO:0000313|Ensembl:ENSP00000417532}; Flags: Fragment;+++[D3DNL3_HUMAN|Unreviewed]SubName: Full=G elongation factor, mitochondrial 1, isoform CRA_c {ECO:0000313|EMBL:EAW78681.1};+++[E5KND5_HUMAN|Unreviewed]RecName: Full=Elongation factor G, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03061}; Short=EF-Gmt {ECO:0000256|HAMAP-Rule:MF_03061}; AltName: Full=Elongation factor G 1, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03061}; Short=mEF-G 1 {ECO:0000256|HAMAP-Rule:MF_03061}; AltName: Full=Elongation factor G1 {ECO:0000256|HAMAP-Rule:MF_03061};+++[E5KND7_HUMAN|Unreviewed]RecName: Full=Elongation factor G, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03061}; Short=EF-Gmt {ECO:0000256|HAMAP-Rule:MF_03061}; AltName: Full=Elongation factor G 1, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03061}; Short=mEF-G 1 {ECO:0000256|HAMAP-Rule:MF_03061}; AltName: Full=Elongation factor G1 {ECO:0000256|HAMAP-Rule:MF_03061};+++[F8WAU4_HUMAN|Unreviewed]SubName: Full=Elongation factor G, mitochondrial {ECO:0000313|Ensembl:ENSP00000417225};+++[H7C5M4_HUMAN|Unreviewed]SubName: Full=Elongation factor G, mitochondrial {ECO:0000313|Ensembl:ENSP00000420272}; Flags: Fragment;"]
[8554,"'PIAS1'",732,728,576,678.666666666667,"04120///Ubiquitin mediated proteolysis+++05160///Hepatitis C+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0016605///PML body+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0019904///protein domain specific binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0019899///enzyme binding+++GO:0061665///SUMO ligase activity+++GO:0008134///transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0050681///androgen receptor binding+++GO:0008270///zinc ion binding+++GO:0003714///transcription corepressor activity+++GO:0003713///transcription coactivator activity","GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0065004///protein-DNA complex assembly+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway+++GO:0051152///positive regulation of smooth muscle cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0045444///fat cell differentiation+++GO:0033235///positive regulation of protein sumoylation+++GO:0008542///visual learning+++GO:0007283///spermatogenesis+++GO:0016925///protein sumoylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043066///negative regulation of apoptotic process+++GO:0030521///androgen receptor signaling pathway+++GO:0007259///JAK-STAT cascade+++GO:0000122///negative regulation of transcription by RNA polymerase II","protein inhibitor of activated STAT 1","[PIAS1_HUMAN|Reviewed]RecName: Full=E3 SUMO-protein ligase PIAS1; EC=2.3.2.-; AltName: Full=DEAD/H box-binding protein 1; AltName: Full=E3 SUMO-protein transferase PIAS1 {ECO:0000305}; AltName: Full=Gu-binding protein; Short=GBP; AltName: Full=Protein inhibitor of activated STAT protein 1; AltName: Full=RNA helicase II-binding protein;+++[A4ZVS7_HUMAN|Unreviewed]SubName: Full=Protein inhibitor of activated STAT1 {ECO:0000313|EMBL:ABP49565.1};+++[A4ZVS8_HUMAN|Unreviewed]SubName: Full=Protein inhibitor of activated STAT1 {ECO:0000313|EMBL:ABP49566.1};+++[H3BS65_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS1 {ECO:0000313|Ensembl:ENSP00000456558}; Flags: Fragment;+++[H3BSI8_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS1 {ECO:0000313|Ensembl:ENSP00000456721};+++[H3BUL7_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS1 {ECO:0000313|Ensembl:ENSP00000457698};+++[Q1XBU8_HUMAN|Unreviewed]SubName: Full=Cell proliferation-inducing protein 23 {ECO:0000313|EMBL:AAX18639.1}; SubName: Full=Protein inhibitor of activated STAT, 1, isoform CRA_b {ECO:0000313|EMBL:EAW77805.1};"]
[8564,"'KMO'",63,73,65,67,"01100///Metabolic pathways+++00380///Tryptophan metabolism",null,"M00038///Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate","R01960///L-Kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)   L-Kynurenine + Oxygen + NADPH + H+ <=> 3-Hydroxy-L-kynurenine + NADP+ + H2O","GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0005615///extracellular space+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol","GO:0016491///oxidoreductase activity+++GO:0050660///flavin adenine dinucleotide binding+++GO:0004497///monooxygenase activity+++GO:0004502///kynurenine 3-monooxygenase activity+++GO:0016174///NAD(P)H oxidase activity+++GO:0071949///FAD binding","GO:0009435///NAD biosynthetic process+++GO:0007568///aging+++GO:0019674///NAD metabolic process+++GO:0071347///cellular response to interleukin-1+++GO:0014049///positive regulation of glutamate secretion+++GO:0034276///kynurenic acid biosynthetic process+++GO:0032496///response to lipopolysaccharide+++GO:0006569///tryptophan catabolic process+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan+++GO:1903296///positive regulation of glutamate secretion, neurotransmission+++GO:0055114///oxidation-reduction process+++GO:0043420///anthranilate metabolic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0070189///kynurenine metabolic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0009651///response to salt stress+++GO:0019805///quinolinate biosynthetic process+++GO:0097052///L-kynurenine metabolic process+++GO:1901216///positive regulation of neuron death","kynurenine 3-monooxygenase","[KMO_HUMAN|Reviewed]RecName: Full=Kynurenine 3-monooxygenase {ECO:0000255|HAMAP-Rule:MF_03018}; EC=1.14.13.9 {ECO:0000255|HAMAP-Rule:MF_03018}; AltName: Full=Kynurenine 3-hydroxylase {ECO:0000255|HAMAP-Rule:MF_03018};+++[A0A024R3S9_HUMAN|Unreviewed]RecName: Full=Kynurenine 3-monooxygenase {ECO:0000256|HAMAP-Rule:MF_03018}; EC=1.14.13.9 {ECO:0000256|HAMAP-Rule:MF_03018}; AltName: Full=Kynurenine 3-hydroxylase {ECO:0000256|HAMAP-Rule:MF_03018};+++[A8K693_HUMAN|Unreviewed]RecName: Full=Kynurenine 3-monooxygenase {ECO:0000256|HAMAP-Rule:MF_03018}; EC=1.14.13.9 {ECO:0000256|HAMAP-Rule:MF_03018}; AltName: Full=Kynurenine 3-hydroxylase {ECO:0000256|HAMAP-Rule:MF_03018};+++[H0Y320_HUMAN|Unreviewed]SubName: Full=Kynurenine 3-monooxygenase {ECO:0000313|Ensembl:ENSP00000355513}; Flags: Fragment;+++[Q9BS61_HUMAN|Unreviewed]RecName: Full=Kynurenine 3-monooxygenase {ECO:0000256|HAMAP-Rule:MF_03018}; EC=1.14.13.9 {ECO:0000256|HAMAP-Rule:MF_03018}; AltName: Full=Kynurenine 3-hydroxylase {ECO:0000256|HAMAP-Rule:MF_03018};"]
[8603,"'FAM193A'",1084,1085,956,1041.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0008290///F-actin capping protein complex+++GO:0016604///nuclear body+++GO:0005913///cell-cell adherens junction","GO:0005198///structural molecule activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0008134///transcription factor binding+++GO:0005516///calmodulin binding+++GO:0042803///protein homodimerization activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0030507///spectrin binding+++GO:0045296///cadherin binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0046982///protein heterodimerization activity+++GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0000902///cell morphogenesis+++GO:0035264///multicellular organism growth+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0043032///positive regulation of macrophage activation+++GO:0030036///actin cytoskeleton organization+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0051016///barbed-end actin filament capping+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0001701///in utero embryonic development+++GO:1903393///positive regulation of adherens junction organization+++GO:0071277///cellular response to calcium ion+++GO:0051017///actin filament bundle assembly+++GO:0023035///CD40 signaling pathway+++GO:0034134///toll-like receptor 2 signaling pathway+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0006915///apoptotic process+++GO:0020027///hemoglobin metabolic process+++GO:0050821///protein stabilization+++GO:1903142///positive regulation of establishment of endothelial barrier+++GO:0051403///stress-activated MAPK cascade+++GO:0006954///inflammatory response+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006351///transcription, DNA-templated+++GO:0034138///toll-like receptor 3 signaling pathway+++GO:0055085///transmembrane transport+++GO:0006884///cell volume homeostasis+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0050871///positive regulation of B cell activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016579///protein deubiquitination+++GO:0030218///erythrocyte differentiation","family with sequence similarity 193 member A","[F193A_HUMAN|Reviewed]RecName: Full=Protein FAM193A; AltName: Full=Protein IT14;+++[A0A1B0GVL4_HUMAN|Unreviewed]SubName: Full=Protein FAM193A {ECO:0000313|Ensembl:ENSP00000490564};+++[D6RFZ4_HUMAN|Unreviewed]SubName: Full=Protein FAM193A {ECO:0000313|Ensembl:ENSP00000421369};+++[E7EUR8_HUMAN|Unreviewed]SubName: Full=Protein FAM193A {ECO:0000313|Ensembl:ENSP00000427260}; Flags: Fragment;"]
[8614,"'STC2'",2648,2386,2804,2612.66666666667,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0048471///perinuclear region of cytoplasm+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0019899///enzyme binding+++GO:0042803///protein homodimerization activity+++GO:0020037///heme binding+++GO:0005179///hormone activity","GO:0071456///cellular response to hypoxia+++GO:0033280///response to vitamin D+++GO:0034976///response to endoplasmic reticulum stress+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0043434///response to peptide hormone+++GO:0040015///negative regulation of multicellular organism growth+++GO:0055074///calcium ion homeostasis+++GO:0010469///regulation of signaling receptor activity+++GO:0046885///regulation of hormone biosynthetic process+++GO:0043687///post-translational protein modification+++GO:0044267///cellular protein metabolic process+++GO:0046697///decidualization+++GO:0007566///embryo implantation+++GO:0006979///response to oxidative stress+++GO:0006874///cellular calcium ion homeostasis+++GO:2001256///regulation of store-operated calcium entry+++GO:0010629///negative regulation of gene expression","stanniocalcin 2","[STC2_HUMAN|Reviewed]RecName: Full=Stanniocalcin-2; Short=STC-2; AltName: Full=Stanniocalcin-related protein; Short=STC-related protein; Short=STCRP; Flags: Precursor;+++[E5RG57_HUMAN|Unreviewed]SubName: Full=Stanniocalcin-2 {ECO:0000313|Ensembl:ENSP00000427816}; Flags: Fragment;+++[H0YB13_HUMAN|Unreviewed]SubName: Full=Stanniocalcin-2 {ECO:0000313|Ensembl:ENSP00000428470}; Flags: Fragment;+++[Q6FHC9_HUMAN|Unreviewed]SubName: Full=STC2 protein {ECO:0000313|EMBL:CAG46624.1}; SubName: Full=Stanniocalcin 2, isoform CRA_a {ECO:0000313|EMBL:EAW61399.1}; SubName: Full=cDNA FLJ14757 fis, clone NT2RP3003242, highly similar to Stanniocalcin-2 {ECO:0000313|EMBL:BAG51363.1}; SubName: Full=cDNA FLJ38572 fis, clone HCHON2006786, highly similar to Stanniocalcin-2 {ECO:0000313|EMBL:BAG53160.1}; SubName: Full=cDNA PSEC0097 fis, clone NT2RP2002139, highly similar to Stanniocalcin-2 {ECO:0000313|EMBL:BAG52131.1}; Flags: Fragment;"]
[864,"'RUNX3'",1,0,0,0.333333333333333,"04658///Th1 and Th2 cell differentiation",{"$nulls":3},"GO:0005634///nucleus+++GO:0016513///core-binding factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0000790///nuclear chromatin+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005730///nucleolus+++GO:0005829///cytosol","GO:0003677///DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0045786///negative regulation of cell cycle+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0002062///chondrocyte differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0071559///response to transforming growth factor beta+++GO:0043378///positive regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0048935///peripheral nervous system neuron development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0030182///neuron differentiation+++GO:0006468///protein phosphorylation+++GO:0030097///hemopoiesis+++GO:0006366///transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","runt related transcription factor 3","[RUNX3_HUMAN|Reviewed]RecName: Full=Runt-related transcription factor 3; AltName: Full=Acute myeloid leukemia 2 protein; AltName: Full=Core-binding factor subunit alpha-3; Short=CBF-alpha-3; AltName: Full=Oncogene AML-2; AltName: Full=Polyomavirus enhancer-binding protein 2 alpha C subunit; Short=PEA2-alpha C; Short=PEBP2-alpha C; AltName: Full=SL3-3 enhancer factor 1 alpha C subunit; AltName: Full=SL3/AKV core-binding factor alpha C subunit;+++[A0A024RAH4_HUMAN|Unreviewed]RecName: Full=Runt-related transcription factor {ECO:0000256|PIRNR:PIRNR009374};+++[O14814_HUMAN|Unreviewed]SubName: Full=Transcription factor AML2 {ECO:0000313|EMBL:AAB80759.2}; Flags: Fragment;+++[Q9Y3R8_HUMAN|Unreviewed]SubName: Full=Core binding factor alpha 3 subunit {ECO:0000313|EMBL:CAB42882.1}; Flags: Fragment;"]
[8651,"'SOCS1'",52,48,92,64,"04120///Ubiquitin mediated proteolysis+++04930///Type II diabetes mellitus+++04630///Jak-STAT signaling pathway+++04380///Osteoclast differentiation+++04917///Prolactin signaling pathway+++04910///Insulin signaling pathway+++05206///MicroRNAs in cancer+++05145///Toxoplasmosis",null,"M00684///JAK-STAT signaling+++M00388///ECS complex",null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005737///cytoplasm+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle","GO:0046935///1-phosphatidylinositol-3-kinase regulator activity+++GO:0004860///protein kinase inhibitor activity+++GO:0005159///insulin-like growth factor receptor binding+++GO:0019901///protein kinase binding+++GO:0019210///kinase inhibitor activity+++GO:0005515///protein binding","GO:0001932///regulation of protein phosphorylation+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0006469///negative regulation of protein kinase activity+++GO:0071230///cellular response to amino acid stimulus+++GO:0045444///fat cell differentiation+++GO:0046425///regulation of JAK-STAT cascade+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0019221///cytokine-mediated signaling pathway+++GO:0007259///JAK-STAT cascade+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway+++GO:0010533///regulation of activation of Janus kinase activity+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0042509///regulation of tyrosine phosphorylation of STAT protein+++GO:0043377///negative regulation of CD8-positive, alpha-beta T cell differentiation+++GO:0040008///regulation of growth+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0033673///negative regulation of kinase activity+++GO:0009968///negative regulation of signal transduction+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0016567///protein ubiquitination+++GO:0050707///regulation of cytokine secretion+++GO:0043372///positive regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0035556///intracellular signal transduction","suppressor of cytokine signaling 1","[SOCS1_HUMAN|Reviewed]RecName: Full=Suppressor of cytokine signaling 1; Short=SOCS-1; AltName: Full=JAK-binding protein; Short=JAB; AltName: Full=STAT-induced STAT inhibitor 1; Short=SSI-1; AltName: Full=Tec-interacting protein 3; Short=TIP-3;+++[Q4JHT5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45719 fis, clone FELNG2001953, highly similar to Suppressor of cytokine signaling 1 {ECO:0000313|EMBL:BAG54535.1};+++[Q9NSA8_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine signalling protein {ECO:0000313|EMBL:CAB92527.1};"]
[8673,"'VAMP8'",3,2,4,3,"04611///Platelet activation+++04130///SNARE interactions in vesicular transport+++04140///Autophagy - animal",{"$nulls":3},"GO:0005764///lysosome+++GO:0031982///vesicle+++GO:0070062///extracellular exosome+++GO:0031902///late endosome membrane+++GO:0005765///lysosomal membrane+++GO:0031901///early endosome membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0098594///mucin granule+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0070821///tertiary granule membrane+++GO:0030667///secretory granule membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0055037///recycling endosome+++GO:0030670///phagocytic vesicle membrane+++GO:0016020///membrane+++GO:0055038///recycling endosome membrane+++GO:0031201///SNARE complex+++GO:0005737///cytoplasm+++GO:0035579///specific granule membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0035577///azurophil granule membrane+++GO:0005769///early endosome","GO:0019869///chloride channel inhibitor activity+++GO:0005515///protein binding","GO:0097352///autophagosome maturation+++GO:1903595///positive regulation of histamine secretion by mast cell+++GO:0046718///viral entry into host cell+++GO:0043312///neutrophil degranulation+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0015031///protein transport+++GO:0061024///membrane organization+++GO:1903531///negative regulation of secretion by cell+++GO:0043308///eosinophil degranulation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0006914///autophagy+++GO:0016240///autophagosome membrane docking+++GO:0070254///mucus secretion+++GO:0016192///vesicle-mediated transport","vesicle associated membrane protein 8","[VAMP8_HUMAN|Reviewed]RecName: Full=Vesicle-associated membrane protein 8 {ECO:0000303|PubMed:12130530}; Short=VAMP-8 {ECO:0000303|PubMed:12130530}; AltName: Full=Endobrevin {ECO:0000303|PubMed:9614193}; Short=EDB {ECO:0000303|PubMed:9614193};+++[B8ZZT4_HUMAN|Unreviewed]SubName: Full=Vesicle-associated membrane protein 8 {ECO:0000313|Ensembl:ENSP00000387094};+++[C9JXZ5_HUMAN|Unreviewed]SubName: Full=Vesicle-associated membrane protein 8 {ECO:0000313|Ensembl:ENSP00000407984};"]
[8693,"'GALNT4'",28.38,48.45,12.5,29.7766666666667,"00512///Mucin type O-glycan biosynthesis+++01100///Metabolic pathways","H00020///Colorectal cancer+++H01439///Williams-Beuren syndrome+++H01193///Familial tumoral calcinosis (FTC)","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046872///metal ion binding+++GO:0030145///manganese ion binding+++GO:0030246///carbohydrate binding+++GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity","GO:0018242///protein O-linked glycosylation via serine+++GO:0018243///protein O-linked glycosylation via threonine+++GO:0006486///protein glycosylation+++GO:0016266///O-glycan processing","polypeptide N-acetylgalactosaminyltransferase 4","[GALT4_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 4; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 4; Short=GalNAc-T4; Short=pp-GaNTase 4; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 4; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4;+++[L8EA58_HUMAN|Unreviewed]SubName: Full=Alternative protein GALNT4 {ECO:0000313|EMBL:CCQ43233.1};"]
[87178,"'PNPT1'",488.99,559.17,767.12,605.093333333333,"03018///RNA degradation+++00230///Purine metabolism+++00240///Pyrimidine metabolism","H00891///Combined oxidative phosphorylation deficiency (COXPD)","M00394///RNA degradosome","R00439///polyribonucleotide:phosphate guanylyltransferase   RNA + Orthophosphate <=> RNA + GDP+++R00440///polyribonucleotide:phosphate cytidylyltransferase   RNA + Orthophosphate <=> RNA + CDP+++R00437///polyribonucleotide:phosphate adenylyltransferase   RNA + Orthophosphate <=> RNA + ADP+++R00438///polyribonucleotide:phosphate uridylyltransferase   RNA + Orthophosphate <=> RNA + UDP","GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0045025///mitochondrial degradosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0042788///polysomal ribosome+++GO:0005758///mitochondrial intermembrane space+++GO:0016020///membrane","GO:0004518///nuclease activity+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0008266///poly(U) RNA binding+++GO:0035198///miRNA binding+++GO:0034046///poly(G) binding+++GO:0003723///RNA binding+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0004527///exonuclease activity+++GO:0004654///polyribonucleotide nucleotidyltransferase activity","GO:0000962///positive regulation of mitochondrial RNA catabolic process+++GO:0006397///mRNA processing+++GO:0060416///response to growth hormone+++GO:0035927///RNA import into mitochondrion+++GO:0006401///RNA catabolic process+++GO:0000964///mitochondrial RNA 5'-end processing+++GO:2000772///regulation of cellular senescence+++GO:0045926///negative regulation of growth+++GO:0000963///mitochondrial RNA processing+++GO:0043631///RNA polyadenylation+++GO:0097222///mitochondrial mRNA polyadenylation+++GO:0035458///cellular response to interferon-beta+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0070207///protein homotrimerization+++GO:0043457///regulation of cellular respiration+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0051591///response to cAMP+++GO:0000965///mitochondrial RNA 3'-end processing+++GO:0071042///nuclear polyadenylation-dependent mRNA catabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0070584///mitochondrion morphogenesis+++GO:0006396///RNA processing+++GO:0097421///liver regeneration+++GO:0000957///mitochondrial RNA catabolic process+++GO:0034599///cellular response to oxidative stress+++GO:0000958///mitochondrial mRNA catabolic process+++GO:0035928///rRNA import into mitochondrion+++GO:0071850///mitotic cell cycle arrest+++GO:0006402///mRNA catabolic process+++GO:2000627///positive regulation of miRNA catabolic process+++GO:0051260///protein homooligomerization","polyribonucleotide nucleotidyltransferase 1","[PNPT1_HUMAN|Reviewed]RecName: Full=Polyribonucleotide nucleotidyltransferase 1, mitochondrial; EC=2.7.7.8; AltName: Full=3'-5' RNA exonuclease OLD35; AltName: Full=PNPase old-35; AltName: Full=Polynucleotide phosphorylase 1; Short=PNPase 1; AltName: Full=Polynucleotide phosphorylase-like protein; Flags: Precursor;+++[F8WBI3_HUMAN|Unreviewed]SubName: Full=Polyribonucleotide nucleotidyltransferase 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000411994};+++[H7BXF6_HUMAN|Unreviewed]SubName: Full=Polyribonucleotide nucleotidyltransferase 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000260604};+++[H7C3C5_HUMAN|Unreviewed]SubName: Full=Polyribonucleotide nucleotidyltransferase 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000411057}; Flags: Fragment;"]
[8732,"'RNGTT'",254,280,253,262.333333333333,"03015///mRNA surveillance pathway",null,null,"R10814///5'-triphospho-[mRNA] phosphohydrolase   5'-Triphospho-[mRNA] + H2O <=> (5')ppPur-mRNA + Orthophosphate+++R03828///GTP:mRNA guanylyltransferase   GTP + (5')ppPur-mRNA <=> Diphosphate + G(5')pppPur-mRNA","GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0004651///polynucleotide 5'-phosphatase activity+++GO:0005525///GTP binding+++GO:0050355///triphosphatase activity+++GO:0016791///phosphatase activity+++GO:0004484///mRNA guanylyltransferase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016740///transferase activity+++GO:0008192///RNA guanylyltransferase activity+++GO:0016787///hydrolase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0000166///nucleotide binding","GO:0006370///7-methylguanosine mRNA capping+++GO:0098507///polynucleotide 5' dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006396///RNA processing+++GO:0006366///transcription by RNA polymerase II+++GO:0008152///metabolic process+++GO:0016032///viral process+++GO:0006397///mRNA processing+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation","RNA guanylyltransferase and 5'-phosphatase","[MCE1_HUMAN|Reviewed]RecName: Full=mRNA-capping enzyme; AltName: Full=HCAP1; AltName: Full=HCE; Includes: RecName: Full=Polynucleotide 5'-triphosphatase; EC=3.1.3.33; AltName: Full=mRNA 5'-triphosphatase; Short=TPase; Includes: RecName: Full=mRNA guanylyltransferase; EC=2.7.7.50; AltName: Full=GTP--RNA guanylyltransferase; Short=GTase;+++[B4DSJ8_HUMAN|Unreviewed]RecName: Full=mRNA-capping enzyme {ECO:0000256|PIRNR:PIRNR036958}; Includes: RecName: Full=Polynucleotide 5'-triphosphatase {ECO:0000256|PIRNR:PIRNR036958}; EC=3.1.3.33 {ECO:0000256|PIRNR:PIRNR036958}; Includes: RecName: Full=mRNA guanylyltransferase {ECO:0000256|PIRNR:PIRNR036958}; EC=2.7.7.50 {ECO:0000256|PIRNR:PIRNR036958}; AltName: Full=GTP--RNA guanylyltransferase {ECO:0000256|PIRNR:PIRNR036958}; Short=GTase {ECO:0000256|PIRNR:PIRNR036958};+++[Q7Z3R6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686J2031 {ECO:0000313|EMBL:CAD97693.1}; Flags: Fragment;"]
[8760,"'CDS2'",1524,1499,1298,1440.33333333333,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++01110///Biosynthesis of secondary metabolites",null,"M00093///Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE","R01799///CTP:phosphatidate cytidyltransferase   CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol","GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum","GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups","GO:0008654///phospholipid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process","CDP-diacylglycerol synthase 2","[CDS2_HUMAN|Reviewed]RecName: Full=Phosphatidate cytidylyltransferase 2; EC=2.7.7.41; AltName: Full=CDP-DAG synthase 2; AltName: Full=CDP-DG synthase 2; AltName: Full=CDP-diacylglycerol synthase 2; Short=CDS 2; AltName: Full=CDP-diglyceride pyrophosphorylase 2; AltName: Full=CDP-diglyceride synthase 2; AltName: Full=CTP:phosphatidate cytidylyltransferase 2;"]
[8784,"'TNFRSF18'",28,8,34,23.3333333333333,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0005515///protein binding+++GO:0005031///tumor necrosis factor-activated receptor activity","GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0045785///positive regulation of cell adhesion+++GO:0002687///positive regulation of leukocyte migration","TNF receptor superfamily member 18","[TNR18_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor receptor superfamily member 18; AltName: Full=Activation-inducible TNFR family receptor; AltName: Full=Glucocorticoid-induced TNFR-related protein; AltName: CD_antigen=CD357; Flags: Precursor;+++[A0A0R7FDM1_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 18 isoform 4 {ECO:0000313|EMBL:AKO62650.1};+++[A8WFP4_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily, member 18 {ECO:0000313|EMBL:AAI52387.1}; Flags: Fragment;+++[J3KT02_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 18 {ECO:0000313|Ensembl:ENSP00000462735};"]
[8802,"'SUCLG1'",424,412,441,425.666666666667,"01120///Microbial metabolism in diverse environments+++01110///Biosynthesis of secondary metabolites+++00640///Propanoate metabolism+++01100///Metabolic pathways+++01200///Carbon metabolism+++01130///Biosynthesis of antibiotics+++00020///Citrate cycle (TCA cycle)","H00469///Mitochondrial DNA depletion syndrome (MDS)","M00011///Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate+++M00009///Citrate cycle (TCA cycle, Krebs cycle)","R00432///Succinate:CoA ligase (GDP-forming)   GTP + Succinate + CoA <=> GDP + Orthophosphate + Succinyl-CoA+++R00727///Succinate:CoA ligase (IDP-forming)   ITP + Succinate + CoA <=> IDP + Orthophosphate + Succinyl-CoA","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0045244///succinate-CoA ligase complex (GDP-forming)","GO:0000166///nucleotide binding+++GO:0048037///cofactor binding+++GO:0004775///succinate-CoA ligase (ADP-forming) activity+++GO:0016874///ligase activity+++GO:0003824///catalytic activity+++GO:0003723///RNA binding+++GO:0004776///succinate-CoA ligase (GDP-forming) activity+++GO:0019003///GDP binding+++GO:0004550///nucleoside diphosphate kinase activity","GO:0006105///succinate metabolic process+++GO:0009142///nucleoside triphosphate biosynthetic process+++GO:0006104///succinyl-CoA metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0006165///nucleoside diphosphate phosphorylation","succinate-CoA ligase alpha subunit","[SUCA_HUMAN|Reviewed]RecName: Full=Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03222}; EC=6.2.1.4 {ECO:0000255|HAMAP-Rule:MF_03222}; EC=6.2.1.5 {ECO:0000255|HAMAP-Rule:MF_03222}; AltName: Full=Succinyl-CoA synthetase subunit alpha {ECO:0000255|HAMAP-Rule:MF_03222}; Short=SCS-alpha {ECO:0000255|HAMAP-Rule:MF_03222}; Flags: Precursor;+++[A8K4W7_HUMAN|Unreviewed]RecName: Full=Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03222}; EC=6.2.1.4 {ECO:0000256|HAMAP-Rule:MF_03222}; EC=6.2.1.5 {ECO:0000256|HAMAP-Rule:MF_03222}; AltName: Full=Succinyl-CoA synthetase subunit alpha {ECO:0000256|HAMAP-Rule:MF_03222}; Short=SCS-alpha {ECO:0000256|HAMAP-Rule:MF_03222};+++[B2R8A1_HUMAN|Unreviewed]RecName: Full=Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03222}; EC=6.2.1.4 {ECO:0000256|HAMAP-Rule:MF_03222}; EC=6.2.1.5 {ECO:0000256|HAMAP-Rule:MF_03222}; AltName: Full=Succinyl-CoA synthetase subunit alpha {ECO:0000256|HAMAP-Rule:MF_03222}; Short=SCS-alpha {ECO:0000256|HAMAP-Rule:MF_03222};+++[H7C233_HUMAN|Unreviewed]SubName: Full=Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial {ECO:0000313|Ensembl:ENSP00000403884}; Flags: Fragment;+++[Q6IAL5_HUMAN|Unreviewed]RecName: Full=Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03222}; EC=6.2.1.4 {ECO:0000256|HAMAP-Rule:MF_03222}; EC=6.2.1.5 {ECO:0000256|HAMAP-Rule:MF_03222}; AltName: Full=Succinyl-CoA synthetase subunit alpha {ECO:0000256|HAMAP-Rule:MF_03222}; Short=SCS-alpha {ECO:0000256|HAMAP-Rule:MF_03222};"]
[8820,"'HESX1'",7,9,5,7,"04550///Signaling pathways regulating pluripotency of stem cells","H02036///Combined pituitary hormone deficiency+++H00254///Growth hormone deficiency+++H01700///Hypopituitarism+++H00544///Septo-optic dysplasia",null,null,"GO:0005634///nucleus","GO:0047485///protein N-terminus binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0043565///sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding","GO:0021983///pituitary gland development+++GO:0007420///brain development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0043584///nose development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0048853///forebrain morphogenesis+++GO:0030916///otic vesicle formation","HESX homeobox 1","[HESX1_HUMAN|Reviewed]RecName: Full=Homeobox expressed in ES cells 1; AltName: Full=Homeobox protein ANF; Short=hAnf;+++[A0A024R364_HUMAN|Unreviewed]SubName: Full=Homeobox, ES cell expressed 1, isoform CRA_a {ECO:0000313|EMBL:EAW65334.1};+++[C9J0A9_HUMAN|Unreviewed]SubName: Full=Homeobox-expressed in ES cells 1 {ECO:0000313|Ensembl:ENSP00000418918};+++[J3KR67_HUMAN|Unreviewed]SubName: Full=Homeobox-expressed in ES cells 1 {ECO:0000313|Ensembl:ENSP00000419615}; Flags: Fragment;"]
[8837,"'CFLAR'",1568.08,1372.48,1431.06,1457.20666666667,"04668///TNF signaling pathway+++04140///Autophagy - animal+++04064///NF-kappa B signaling pathway+++04217///Necroptosis+++05142///Chagas disease (American trypanosomiasis)+++04210///Apoptosis","H00837///Leber congenital amaurosis (LCR)+++H00527///Retinitis pigmentosa (RP)","M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP","R08240///6-thioinosine 5'-monophosphate:NAD+ oxidoreductase 6-Thioinosine-5'-monophosphate + NAD+ + H2O <=> 6-Thioxanthine 5'-monophosphate + NADH + H++++R01130///IMP:NAD+ oxidoreductase IMP + NAD+ + H2O <=> Xanthosine 5'-phosphate + NADH + H+","GO:0097342///ripoptosome+++GO:0005737///cytoplasm+++GO:0031264///death-inducing signaling complex+++GO:0005829///cytosol+++GO:0031265///CD95 death-inducing signaling complex+++GO:0045121///membrane raft","GO:0008234///cysteine-type peptidase activity+++GO:0005123///death receptor binding+++GO:0005515///protein binding+++GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002020///protease binding+++GO:0016504///peptidase activator activity+++GO:0046982///protein heterodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0008047///enzyme activator activity+++GO:0004197///cysteine-type endopeptidase activity","GO:0071456///cellular response to hypoxia+++GO:0006915///apoptotic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0060544///regulation of necroptotic process+++GO:0001666///response to hypoxia+++GO:0043403///skeletal muscle tissue regeneration+++GO:0042981///regulation of apoptotic process+++GO:0009617///response to bacterium+++GO:0010976///positive regulation of neuron projection development+++GO:0014732///skeletal muscle atrophy+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:1904036///negative regulation of epithelial cell apoptotic process+++GO:0032869///cellular response to insulin stimulus+++GO:0060546///negative regulation of necroptotic process+++GO:0072126///positive regulation of glomerular mesangial cell proliferation+++GO:0071732///cellular response to nitric oxide+++GO:2000347///positive regulation of hepatocyte proliferation+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0033574///response to testosterone+++GO:1903845///negative regulation of cellular response to transforming growth factor beta stimulus+++GO:0043085///positive regulation of catalytic activity+++GO:0006508///proteolysis+++GO:1903944///negative regulation of hepatocyte apoptotic process+++GO:0016032///viral process+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0014866///skeletal myofibril assembly+++GO:0071392///cellular response to estradiol stimulus+++GO:1903055///positive regulation of extracellular matrix organization+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0007519///skeletal muscle tissue development+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0010667///negative regulation of cardiac muscle cell apoptotic process+++GO:1901740///negative regulation of myoblast fusion+++GO:0010952///positive regulation of peptidase activity+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043066///negative regulation of apoptotic process+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process+++GO:0071364///cellular response to epidermal growth factor stimulus","CASP8 and FADD like apoptosis regulator","[CFLAR_HUMAN|Reviewed]RecName: Full=CASP8 and FADD-like apoptosis regulator; AltName: Full=Caspase homolog; Short=CASH; AltName: Full=Caspase-eight-related protein; Short=Casper; AltName: Full=Caspase-like apoptosis regulatory protein; Short=CLARP; AltName: Full=Cellular FLICE-like inhibitory protein; Short=c-FLIP; AltName: Full=FADD-like antiapoptotic molecule 1; Short=FLAME-1; AltName: Full=Inhibitor of FLICE; Short=I-FLICE; AltName: Full=MACH-related inducer of toxicity; Short=MRIT; AltName: Full=Usurpin; Contains: RecName: Full=CASP8 and FADD-like apoptosis regulator subunit p43; Contains: RecName: Full=CASP8 and FADD-like apoptosis regulator subunit p12; Flags: Precursor;+++[A0A024R3Y3_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator, isoform CRA_d {ECO:0000313|EMBL:EAW70240.1};+++[A0A024R3Z7_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator, isoform CRA_c {ECO:0000313|EMBL:EAW70243.1}; SubName: Full=Testis secretory sperm-binding protein Li 233m {ECO:0000313|EMBL:AEE60951.1};+++[A0A0A0MR92_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000339326};+++[A0A336TY74_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator, isoform CRA_a {ECO:0000313|EMBL:EAW70235.1}; SubName: Full=Usurpin-beta splice variant {ECO:0000313|EMBL:AMY98472.1};+++[B4E361_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59611, highly similar to CASP8 and FADD-like apoptosis regulator {ECO:0000313|EMBL:BAG65373.1};+++[C9J408_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000411897}; Flags: Fragment;+++[C9J4Q0_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000391029}; Flags: Fragment;+++[C9JSU3_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000409570}; Flags: Fragment;+++[C9JV51_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000412882}; Flags: Fragment;+++[E9PAP3_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000378580};+++[F8WBH9_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000398551};+++[M0QY57_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000469608};+++[M0QYM0_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000469917}; Flags: Fragment;+++[M0R1A8_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator {ECO:0000313|Ensembl:ENSP00000471749}; Flags: Fragment;+++[Q59F61_HUMAN|Unreviewed]SubName: Full=CASP8 and FADD-like apoptosis regulator variant {ECO:0000313|EMBL:BAD92837.1}; Flags: Fragment;"]
[8862,"'APLN'",44,21,33,32.6666666666667,"04371///Apelin signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0005576///extracellular region","GO:0005102///signaling receptor binding+++GO:0042803///protein homodimerization activity+++GO:0005179///hormone activity+++GO:0031704///apelin receptor binding","GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0006955///immune response+++GO:0050878///regulation of body fluid levels+++GO:0045823///positive regulation of heart contraction+++GO:0042327///positive regulation of phosphorylation+++GO:0043576///regulation of respiratory gaseous exchange+++GO:0007369///gastrulation+++GO:0045776///negative regulation of blood pressure+++GO:0010629///negative regulation of gene expression+++GO:0031652///positive regulation of heat generation+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0042756///drinking behavior+++GO:1904022///positive regulation of G protein-coupled receptor internalization+++GO:0097755///positive regulation of blood vessel diameter+++GO:0007595///lactation+++GO:0060976///coronary vasculature development+++GO:0002026///regulation of the force of heart contraction+++GO:0007275///multicellular organism development+++GO:0007631///feeding behavior+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:0051466///positive regulation of corticotropin-releasing hormone secretion+++GO:0001525///angiogenesis+++GO:0060183///apelin receptor signaling pathway+++GO:0045906///negative regulation of vasoconstriction+++GO:0010469///regulation of signaling receptor activity+++GO:0051461///positive regulation of corticotropin secretion+++GO:1905564///positive regulation of vascular endothelial cell proliferation","apelin","[APEL_HUMAN|Reviewed]RecName: Full=Apelin; AltName: Full=APJ endogenous ligand; Contains: RecName: Full=Apelin-36; Contains: RecName: Full=Apelin-31; Contains: RecName: Full=Apelin-28; Contains: RecName: Full=Apelin-13; Flags: Precursor;+++[D3DTF8_HUMAN|Unreviewed]SubName: Full=Apelin, AGTRL1 ligand, isoform CRA_a {ECO:0000313|EMBL:EAX11829.1};"]
[8882,"'ZPR1'",614,679,698,663.666666666667,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0032797///SMN complex+++GO:0097504///Gemini of coiled bodies+++GO:0042995///cell projection+++GO:0015030///Cajal body+++GO:0030424///axon+++GO:0043204///perikaryon+++GO:0005654///nucleoplasm+++GO:0030426///growth cone","GO:0005515///protein binding+++GO:0031369///translation initiation factor binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0030971///receptor tyrosine kinase binding","GO:1990261///pre-mRNA catabolic process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0001834///trophectodermal cell proliferation+++GO:0001833///inner cell mass cell proliferation+++GO:2000672///negative regulation of motor neuron apoptotic process+++GO:0045927///positive regulation of growth+++GO:0031641///regulation of myelination+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0008380///RNA splicing+++GO:0033120///positive regulation of RNA splicing+++GO:0007165///signal transduction+++GO:0021510///spinal cord development+++GO:0008283///cell proliferation+++GO:0006397///mRNA processing+++GO:0000226///microtubule cytoskeleton organization+++GO:0030576///Cajal body organization+++GO:0042023///DNA endoreduplication+++GO:1902742///apoptotic process involved in development+++GO:0030154///cell differentiation+++GO:0010628///positive regulation of gene expression+++GO:0071931///positive regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0061564///axon development","ZPR1 zinc finger","[ZPR1_HUMAN|Reviewed]RecName: Full=Zinc finger protein ZPR1; AltName: Full=Zinc finger protein 259;+++[F8WBC5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZPR1 {ECO:0000313|Ensembl:ENSP00000410141};+++[H7BZM7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZPR1 {ECO:0000313|Ensembl:ENSP00000390391}; Flags: Fragment;+++[H7BZS1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZPR1 {ECO:0000313|Ensembl:ENSP00000391077}; Flags: Fragment;+++[H7C0E5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZPR1 {ECO:0000313|Ensembl:ENSP00000394495}; Flags: Fragment;+++[H7C449_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ZPR1 {ECO:0000313|Ensembl:ENSP00000415505}; Flags: Fragment;"]
[8897,"'MTMR3'",1921,2219,1692,1944,"00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane","GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0046872///metal ion binding+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0005515///protein binding+++GO:0019903///protein phosphatase binding","GO:0016236///macroautophagy+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:2000785///regulation of autophagosome assembly+++GO:0006629///lipid metabolic process+++GO:1904562///phosphatidylinositol 5-phosphate metabolic process+++GO:0006470///protein dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0016311///dephosphorylation+++GO:0060304///regulation of phosphatidylinositol dephosphorylation+++GO:0042149///cellular response to glucose starvation","myotubularin related protein 3","[MTMR3_HUMAN|Reviewed]RecName: Full=Myotubularin-related protein 3; EC=3.1.3.48 {ECO:0000269|PubMed:10733931}; AltName: Full=FYVE domain-containing dual specificity protein phosphatase 1; Short=FYVE-DSP1; AltName: Full=Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; EC=3.1.3.95 {ECO:0000269|PubMed:11676921}; AltName: Full=Phosphatidylinositol-3-phosphate phosphatase; EC=3.1.3.64 {ECO:0000269|PubMed:11676921}; AltName: Full=Zinc finger FYVE domain-containing protein 10;+++[A0A024R1I2_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 3, isoform CRA_d {ECO:0000313|EMBL:EAW59853.1};+++[A7E2W2_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 3 {ECO:0000313|EMBL:AAI51218.1};+++[C9JLU3_HUMAN|Unreviewed]SubName: Full=Myotubularin-related protein 3 {ECO:0000313|Ensembl:ENSP00000409063}; Flags: Fragment;+++[G5E953_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 3, isoform CRA_e {ECO:0000313|EMBL:EAW59854.1}; SubName: Full=Myotubularin-related protein 3 {ECO:0000313|Ensembl:ENSP00000318070};"]
[890,"'CCNA2'",162,243,196,200.333333333333,"05169///Epstein-Barr virus infection+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation+++04152///AMPK signaling pathway+++05203///Viral carcinogenesis+++05165///Human papillomavirus infection+++05161///Hepatitis B+++04218///Cellular senescence",null,"M00693///Cell cycle - G2/M transition",null,"GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0097124///cyclin A2-CDK2 complex+++GO:0001940///male pronucleus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0001939///female pronucleus+++GO:0005829///cytosol","GO:0004672///protein kinase activity+++GO:0019904///protein domain specific binding+++GO:0097472///cyclin-dependent protein kinase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity","GO:0071732///cellular response to nitric oxide+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0090102///cochlea development+++GO:0008284///positive regulation of cell proliferation+++GO:0016572///histone phosphorylation+++GO:0033762///response to glucagon+++GO:0007265///Ras protein signal transduction+++GO:0071407///cellular response to organic cyclic compound+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032355///response to estradiol+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0006275///regulation of DNA replication+++GO:0071373///cellular response to luteinizing hormone stimulus+++GO:0071456///cellular response to hypoxia+++GO:0071314///cellular response to cocaine+++GO:0016032///viral process+++GO:0044320///cellular response to leptin stimulus+++GO:0031100///animal organ regeneration+++GO:0007049///cell cycle+++GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:0051301///cell division+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division+++GO:0000278///mitotic cell cycle+++GO:0044843///cell cycle G1/S phase transition+++GO:0045787///positive regulation of cell cycle+++GO:0016579///protein deubiquitination+++GO:0071392///cellular response to estradiol stimulus","cyclin A2","[CCNA2_HUMAN|Reviewed]RecName: Full=Cyclin-A2 {ECO:0000312|HGNC:HGNC:1578}; Short=Cyclin-A {ECO:0000303|PubMed:1967822}; AltName: Full=Cyclin A {ECO:0000303|PubMed:1967822};"]
[8938,"'BAIAP3'",72,51,70,64.3333333333333,"05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0031045///dense core granule+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0032588///trans-Golgi network membrane+++GO:0055038///recycling endosome membrane+++GO:0031902///late endosome membrane","GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding+++GO:0005515///protein binding","GO:1905413///regulation of dense core granule exocytosis+++GO:0006887///exocytosis+++GO:1990502///dense core granule maturation+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0001956///positive regulation of neurotransmitter secretion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0032228///regulation of synaptic transmission, GABAergic","BAI1 associated protein 3","[BAIP3_HUMAN|Reviewed]RecName: Full=BAI1-associated protein 3 {ECO:0000303|PubMed:9790924}; Short=BAP3 {ECO:0000303|PubMed:9790924}; AltName: Full=Brain-specific angiogenesis inhibitor I-associated protein 3 {ECO:0000303|PubMed:9790924};+++[H3BPP9_HUMAN|Unreviewed]SubName: Full=BAI1-associated protein 3 {ECO:0000313|Ensembl:ENSP00000455414}; Flags: Fragment;+++[H3BV46_HUMAN|Unreviewed]SubName: Full=BAI1-associated protein 3 {ECO:0000313|Ensembl:ENSP00000457947}; Flags: Fragment;"]
[8942,"'KYNU'",1,0,0,0.333333333333333,"00380///Tryptophan metabolism+++01100///Metabolic pathways","H02087///Vertebral, cardiac, renal, and limb defects syndrome+++H01583///Hydroxykynureninuria","M00038///Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate","R00987///L-Kynurenine hydrolase   L-Kynurenine + H2O <=> Anthranilate + L-Alanine+++R03936///Formylkynurenine hydrolase   L-Formylkynurenine + H2O <=> Formylanthranilate + L-Alanine+++R02668///3-Hydroxy-L-kynurenine hydrolase   3-Hydroxy-L-kynurenine + H2O <=> 3-Hydroxyanthranilate + L-Alanine","GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity+++GO:0061981///3-hydroxykynureninase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0003824///catalytic activity+++GO:0030429///kynureninase activity+++GO:0016787///hydrolase activity","GO:0034516///response to vitamin B6+++GO:0007568///aging+++GO:0097053///L-kynurenine catabolic process+++GO:0019805///quinolinate biosynthetic process+++GO:0009435///NAD biosynthetic process+++GO:0019441///tryptophan catabolic process to kynurenine+++GO:0034354///'de novo' NAD biosynthetic process from tryptophan+++GO:0034341///response to interferon-gamma+++GO:0006569///tryptophan catabolic process+++GO:0019442///tryptophan catabolic process to acetyl-CoA+++GO:0043420///anthranilate metabolic process+++GO:0019363///pyridine nucleotide biosynthetic process","kynureninase","[KYNU_HUMAN|Reviewed]RecName: Full=Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017}; EC=3.7.1.3 {ECO:0000255|HAMAP-Rule:MF_03017, ECO:0000269|PubMed:11985583, ECO:0000269|PubMed:17300176, ECO:0000269|PubMed:8706755, ECO:0000269|PubMed:9180257}; AltName: Full=L-kynurenine hydrolase {ECO:0000255|HAMAP-Rule:MF_03017};+++[A0A087WYM2_HUMAN|Unreviewed]SubName: Full=Kynureninase {ECO:0000313|Ensembl:ENSP00000481930}; Flags: Fragment;+++[A0A087WYQ7_HUMAN|Unreviewed]SubName: Full=Kynureninase {ECO:0000313|Ensembl:ENSP00000482009}; Flags: Fragment;+++[A0A087X297_HUMAN|Unreviewed]SubName: Full=Kynureninase {ECO:0000313|Ensembl:ENSP00000484801}; Flags: Fragment;+++[A8K4D5_HUMAN|Unreviewed]RecName: Full=Kynureninase {ECO:0000256|HAMAP-Rule:MF_03017, ECO:0000256|PIRNR:PIRNR038800}; EC=3.7.1.3 {ECO:0000256|HAMAP-Rule:MF_03017, ECO:0000256|PIRNR:PIRNR038800}; AltName: Full=L-kynurenine hydrolase {ECO:0000256|HAMAP-Rule:MF_03017};+++[A8K7T0_HUMAN|Unreviewed]RecName: Full=Kynureninase {ECO:0000256|HAMAP-Rule:MF_03017, ECO:0000256|PIRNR:PIRNR038800}; EC=3.7.1.3 {ECO:0000256|HAMAP-Rule:MF_03017, ECO:0000256|PIRNR:PIRNR038800}; AltName: Full=L-kynurenine hydrolase {ECO:0000256|HAMAP-Rule:MF_03017};+++[B8ZZA3_HUMAN|Unreviewed]SubName: Full=Kynureninase {ECO:0000313|Ensembl:ENSP00000387296};+++[F8WEP1_HUMAN|Unreviewed]SubName: Full=Kynureninase {ECO:0000313|Ensembl:ENSP00000401190};+++[Q53SX6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KYNU {ECO:0000313|EMBL:AAY14727.1}; Flags: Fragment;+++[Q53SY0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KYNU {ECO:0000313|EMBL:AAX93159.1}; Flags: Fragment;"]
[89849,"'ATG16L2'",47,38,36,40.3333333333333,"04140///Autophagy - animal",{"$nulls":3},"GO:0000421///autophagosome membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm",null,"GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0039689///negative stranded viral RNA replication+++GO:0000045///autophagosome assembly","autophagy related 16 like 2","[A16L2_HUMAN|Reviewed]RecName: Full=Autophagy-related protein 16-2; AltName: Full=APG16-like 2; AltName: Full=WD repeat-containing protein 80;+++[F5GWM4_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000400705};+++[F5GWZ9_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000441189};+++[F5H7B6_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000442635};+++[H0YF72_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000437412}; Flags: Fragment;+++[H0YFC3_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000437932}; Flags: Fragment;+++[H0YFG0_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000438474}; Flags: Fragment;+++[H0YFZ7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000441132}; Flags: Fragment;+++[H0YG45_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000441747}; Flags: Fragment;+++[H0YG67_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000441989}; Flags: Fragment;+++[H0YGE3_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000442931}; Flags: Fragment;+++[H0YGJ8_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 16-2 {ECO:0000313|Ensembl:ENSP00000443569}; Flags: Fragment;+++[Q2VPK0_HUMAN|Unreviewed]SubName: Full=ATG16L2 protein {ECO:0000313|EMBL:AAI08673.1}; Flags: Fragment;+++[Q9H7Q5_HUMAN|Unreviewed]SubName: Full=FLJ00012 protein {ECO:0000313|EMBL:BAB15713.1}; Flags: Fragment;"]
[8987,"'STBD1'",37.7,24.51,35.41,32.54,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0034045///phagophore assembly site membrane+++GO:0030315///T-tubule+++GO:0070821///tertiary granule membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005789///endoplasmic reticulum membrane","GO:2001069///glycogen binding+++GO:2001070///starch binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0030247///polysaccharide binding+++GO:0030246///carbohydrate binding","GO:0005980///glycogen catabolic process+++GO:0006914///autophagy+++GO:0005975///carbohydrate metabolic process+++GO:0046907///intracellular transport+++GO:0061723///glycophagy+++GO:0005977///glycogen metabolic process+++GO:0043312///neutrophil degranulation","starch binding domain 1","[STBD1_HUMAN|Reviewed]RecName: Full=Starch-binding domain-containing protein 1 {ECO:0000303|PubMed:20810658}; AltName: Full=Genethonin-1 {ECO:0000303|PubMed:20810658}; AltName: Full=Glycophagy cargo receptor STBD1 {ECO:0000305};"]
[8992,"'ATP6V0E1'",2759,3171,3548,3159.33333333333,"04966///Collecting duct acid secretion+++05165///Human papillomavirus infection+++05323///Rheumatoid arthritis+++04721///Synaptic vesicle cycle+++00190///Oxidative phosphorylation+++04145///Phagosome+++01100///Metabolic pathways+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05110///Vibrio cholerae infection",null,"M00160///V-type ATPase, eukaryotes",null,"GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0010008///endosome membrane+++GO:0030670///phagocytic vesicle membrane","GO:0015078///proton transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0042625///ATPase coupled ion transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0005215///transporter activity","GO:0016241///regulation of macroautophagy+++GO:0055085///transmembrane transport+++GO:0008286///insulin receptor signaling pathway+++GO:0033572///transferrin transport+++GO:0015991///ATP hydrolysis coupled proton transport+++GO:0007035///vacuolar acidification+++GO:0006811///ion transport+++GO:1902600///proton transmembrane transport+++GO:0034220///ion transmembrane transport","ATPase H+ transporting V0 subunit e1","[VA0E1_HUMAN|Reviewed]RecName: Full=V-type proton ATPase subunit e 1; Short=V-ATPase subunit e 1; AltName: Full=V-ATPase 9.2 kDa membrane accessory protein; AltName: Full=V-ATPase M9.2 subunit; AltName: Full=Vacuolar proton pump subunit e 1;+++[E5RHL5_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit e 1 {ECO:0000313|Ensembl:ENSP00000430896};+++[J3KN48_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit e 1 {ECO:0000313|Ensembl:ENSP00000265093};"]
[90075,"'ZNF30'",47,38,25,36.6666666666667,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 30","[ZNF30_HUMAN|Reviewed]RecName: Full=Zinc finger protein 30; AltName: Full=Zinc finger protein KOX28;+++[L8E9Q4_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF30 {ECO:0000313|EMBL:CCQ43078.1};+++[V9GYJ2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 30 {ECO:0000313|Ensembl:ENSP00000476813}; Flags: Fragment;"]
[9014,"'TAF1B'",97,88,83,89.3333333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0070860///RNA polymerase I core factor complex+++GO:0005668///RNA polymerase transcription factor SL1 complex","GO:0005515///protein binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0017025///TBP-class protein binding+++GO:0003677///DNA binding","GO:0045815///positive regulation of gene expression, epigenetic+++GO:0006360///transcription by RNA polymerase I+++GO:0006351///transcription, DNA-templated+++GO:0001188///RNA polymerase I preinitiation complex assembly+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0042790///nucleolar large rRNA transcription by RNA polymerase I","TATA-box binding protein associated factor, RNA polymerase I subunit B","[TAF1B_HUMAN|Reviewed]RecName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit B; AltName: Full=RNA polymerase I-specific TBP-associated factor 63 kDa; Short=TAFI63; AltName: Full=TATA box-binding protein-associated factor 1B; Short=TBP-associated factor 1B; AltName: Full=Transcription initiation factor SL1/TIF-IB subunit B;+++[F8WDU0_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit B {ECO:0000313|Ensembl:ENSP00000402955};+++[F8WE32_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit B {ECO:0000313|Ensembl:ENSP00000414184};+++[U3KQ75_HUMAN|Unreviewed]SubName: Full=TATA box-binding protein-associated factor RNA polymerase I subunit B {ECO:0000313|Ensembl:ENSP00000475608}; Flags: Fragment;"]
[9026,"'HIP1R'",488,446,410,448,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0030122///AP-2 adaptor complex+++GO:0097060///synaptic membrane+++GO:0030479///actin cortical patch+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0012505///endomembrane system+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005938///cell cortex+++GO:0005829///cytosol+++GO:0043197///dendritic spine+++GO:0032839///dendrite cytoplasm+++GO:0005905///clathrin-coated pit+++GO:0043025///neuronal cell body+++GO:0030136///clathrin-coated vesicle+++GO:0014069///postsynaptic density+++GO:0032587///ruffle membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0042803///protein homodimerization activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0051015///actin filament binding+++GO:0030276///clathrin binding+++GO:0046982///protein heterodimerization activity+++GO:0035615///clathrin adaptor activity+++GO:0017124///SH3 domain binding+++GO:0003779///actin binding+++GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0005543///phospholipid binding+++GO:0032051///clathrin light chain binding","GO:0007015///actin filament organization+++GO:0050821///protein stabilization+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0030100///regulation of endocytosis+++GO:0048268///clathrin coat assembly+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:2000588///positive regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0006897///endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0030837///negative regulation of actin filament polymerization+++GO:0060453///regulation of gastric acid secretion+++GO:0043066///negative regulation of apoptotic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0034316///negative regulation of Arp2/3 complex-mediated actin nucleation+++GO:0032092///positive regulation of protein binding+++GO:0055123///digestive system development+++GO:1905445///positive regulation of clathrin coat assembly+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0061024///membrane organization","huntingtin interacting protein 1 related","[HIP1R_HUMAN|Reviewed]RecName: Full=Huntingtin-interacting protein 1-related protein; Short=HIP1-related protein; AltName: Full=Huntingtin-interacting protein 12; Short=HIP-12;+++[A0A024RBR4_HUMAN|Unreviewed]SubName: Full=Huntingtin interacting protein 1 related, isoform CRA_a {ECO:0000313|EMBL:EAW98347.1};+++[B3KQW8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33218 fis, clone ASTRO2000381, highly similar to Huntingtin-interacting protein 1 {ECO:0000313|EMBL:BAG52180.1};+++[B4DPL0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50827, highly similar to Huntingtin-interacting protein 1 {ECO:0000313|EMBL:BAG60622.1};+++[H0YH66_HUMAN|Unreviewed]SubName: Full=Huntingtin-interacting protein 1-related protein {ECO:0000313|Ensembl:ENSP00000446236}; Flags: Fragment;"]
[90321,"'ZNF766'",190,198,171,186.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 766","[ZN766_HUMAN|Reviewed]RecName: Full=Zinc finger protein 766;+++[A0A0B4J2B2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSP00000471965};+++[G3XAE0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSP00000468950};+++[M0QXI4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSP00000469186}; Flags: Fragment;+++[M0R139_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSP00000471620}; Flags: Fragment;+++[M0R1P9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSP00000472041}; Flags: Fragment;+++[M0R2P3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSP00000472708};+++[M0R2R1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 766 {ECO:0000313|Ensembl:ENSP00000472743}; Flags: Fragment;+++[Q08EK0_HUMAN|Unreviewed]SubName: Full=ZNF766 protein {ECO:0000313|EMBL:AAI09202.1};"]
[90427,"'BMF'",1056,633,549,746,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0016459///myosin complex+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0001669///acrosomal vesicle+++GO:0005741///mitochondrial outer membrane","GO:0005515///protein binding","GO:0034644///cellular response to UV+++GO:0010507///negative regulation of autophagy+++GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0043276///anoikis+++GO:0032464///positive regulation of protein homooligomerization+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0006915///apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0043065///positive regulation of apoptotic process","Bcl2 modifying factor","[BMF_HUMAN|Reviewed]RecName: Full=Bcl-2-modifying factor;+++[H0YK50_HUMAN|Unreviewed]SubName: Full=Bcl-2-modifying factor {ECO:0000313|Ensembl:ENSP00000452660}; Flags: Fragment;+++[H0YNT3_HUMAN|Unreviewed]SubName: Full=Bcl-2-modifying factor {ECO:0000313|Ensembl:ENSP00000454142}; Flags: Fragment;"]
[9048,"'ARTN'",7,5,7,6.33333333333333,{"$nulls":4},"GO:0042405///nuclear inclusion body+++GO:0000784///nuclear chromosome, telomeric region+++GO:0035861///site of double-strand break+++GO:0005657///replication fork+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0000781///chromosome, telomeric region+++GO:0030870///Mre11 complex+++GO:0016605///PML body+++GO:0005694///chromosome","GO:0008083///growth factor activity+++GO:0008134///transcription factor binding+++GO:0003684///damaged DNA binding+++GO:0047485///protein N-terminus binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding","GO:0007411///axon guidance+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:0007050///cell cycle arrest+++GO:0006302///double-strand break repair+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0007422///peripheral nervous system development+++GO:1904354///negative regulation of telomere capping+++GO:0030174///regulation of DNA-dependent DNA replication initiation+++GO:0007049///cell cycle+++GO:0010469///regulation of signaling receptor activity+++GO:0008283///cell proliferation+++GO:0016233///telomere capping+++GO:0006260///DNA replication+++GO:0032508///DNA duplex unwinding+++GO:0000077///DNA damage checkpoint+++GO:0090656///t-circle formation+++GO:0001701///in utero embryonic development+++GO:0007405///neuroblast proliferation+++GO:0031860///telomeric 3' overhang formation+++GO:0000165///MAPK cascade+++GO:0045190///isotype switching+++GO:0000723///telomere maintenance+++GO:0097021///lymphocyte migration into lymphoid organs+++GO:0033674///positive regulation of kinase activity+++GO:0050885///neuromuscular process controlling balance+++GO:0051321///meiotic cell cycle+++GO:0001832///blastocyst growth+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0050930///induction of positive chemotaxis+++GO:0061146///Peyer's patch morphogenesis+++GO:0007093///mitotic cell cycle checkpoint+++GO:0042770///signal transduction in response to DNA damage+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0000729///DNA double-strand break processing+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0032206///positive regulation of telomere maintenance+++GO:0090737///telomere maintenance via telomere trimming+++GO:0007165///signal transduction","artemin","[ARTN_HUMAN|Reviewed]RecName: Full=Artemin; AltName: Full=Enovin; AltName: Full=Neublastin; Flags: Precursor;+++[A0A087X1V5_HUMAN|Unreviewed]SubName: Full=Nibrin {ECO:0000313|Ensembl:ENSP00000484487}; Flags: Fragment;+++[A0PJ71_HUMAN|Unreviewed]SubName: Full=NBN protein {ECO:0000313|EMBL:AAH16762.1}; Flags: Fragment;+++[A6H8Y5_HUMAN|Unreviewed]RecName: Full=Nibrin {ECO:0000256|PIRNR:PIRNR011869};+++[D3DPX9_HUMAN|Unreviewed]SubName: Full=Artemin, isoform CRA_b {ECO:0000313|EMBL:EAX07076.1};+++[E2QRP0_HUMAN|Unreviewed]SubName: Full=Nibrin {ECO:0000313|Ensembl:ENSP00000379551};+++[E5RGN7_HUMAN|Unreviewed]SubName: Full=Nibrin {ECO:0000313|Ensembl:ENSP00000429971}; Flags: Fragment;+++[E5RGR7_HUMAN|Unreviewed]SubName: Full=Nibrin {ECO:0000313|Ensembl:ENSP00000428717}; Flags: Fragment;+++[E5RGU1_HUMAN|Unreviewed]SubName: Full=Nibrin {ECO:0000313|Ensembl:ENSP00000430983}; Flags: Fragment;+++[E9PIK2_HUMAN|Unreviewed]SubName: Full=Artemin {ECO:0000313|Ensembl:ENSP00000435804}; Flags: Fragment;+++[E9PLG3_HUMAN|Unreviewed]SubName: Full=Artemin {ECO:0000313|Ensembl:ENSP00000435140};+++[E9PN22_HUMAN|Unreviewed]SubName: Full=Artemin {ECO:0000313|Ensembl:ENSP00000434856}; Flags: Fragment;"]
[90589,"'ZNF625'",19,20,11,16.6666666666667,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","zinc finger protein 625","[ZN625_HUMAN|Reviewed]RecName: Full=Zinc finger protein 625;+++[H7C2C9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 625 {ECO:0000313|Ensembl:ENSP00000405156}; Flags: Fragment;"]
[90627,"'STARD13'",213,237,160,203.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031966///mitochondrial membrane+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005811///lipid droplet","GO:0005096///GTPase activator activity+++GO:0008289///lipid binding+++GO:0005515///protein binding","GO:0097498///endothelial tube lumen extension+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0043547///positive regulation of GTPase activity+++GO:0043542///endothelial cell migration+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","StAR related lipid transfer domain containing 13","[STA13_HUMAN|Reviewed]RecName: Full=StAR-related lipid transfer protein 13; AltName: Full=46H23.2; AltName: Full=Deleted in liver cancer 2 protein; Short=DLC-2; AltName: Full=Rho GTPase-activating protein; AltName: Full=START domain-containing protein 13; Short=StARD13;+++[A0A024RDV4_HUMAN|Unreviewed]SubName: Full=START domain containing 13, isoform CRA_a {ECO:0000313|EMBL:EAX08530.1};+++[B2R789_HUMAN|Unreviewed]SubName: Full=START domain containing 13, isoform CRA_b {ECO:0000313|EMBL:EAX08528.1}; SubName: Full=cDNA, FLJ93332, Homo sapiens START domain containing 13 (STARD13), transcriptvariant gamma, mRNA {ECO:0000313|EMBL:BAG35736.1};+++[B3KRK6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34485 fis, clone HLUNG2004170, highly similar to StAR-related lipid transfer protein 13 {ECO:0000313|EMBL:BAG52418.1};+++[H3BRG5_HUMAN|Unreviewed]SubName: Full=StAR-related lipid transfer protein 13 {ECO:0000313|Ensembl:ENSP00000456233}; Flags: Fragment;+++[H3BUW7_HUMAN|Unreviewed]SubName: Full=StAR-related lipid transfer protein 13 {ECO:0000313|Ensembl:ENSP00000457840};"]
[90809,"'PIP4P1'",401,439,533,457.666666666667,"04070///Phosphatidylinositol signaling system",null,"M00296///BER complex","R08981///1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase   1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 5-phosphate + Orthophosphate","GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0034597///phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity","GO:0006644///phospholipid metabolic process+++GO:0046856///phosphatidylinositol dephosphorylation","phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1","[PP4P1_HUMAN|Reviewed]RecName: Full=Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Short=Type 1 PtdIns-4,5-P2 4-Ptase; EC=3.1.3.78; AltName: Full=PtdIns-4,5-P2 4-Ptase I; AltName: Full=Transmembrane protein 55B;+++[G3V5T5_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol-4,5-bisphosphate 4-phosphatase {ECO:0000256|RuleBase:RU365008}; EC=3.1.3.78 {ECO:0000256|RuleBase:RU365008}; Flags: Fragment;+++[H0YJ90_HUMAN|Unreviewed]RecName: Full=Phosphatidylinositol-4,5-bisphosphate 4-phosphatase {ECO:0000256|RuleBase:RU365008}; EC=3.1.3.78 {ECO:0000256|RuleBase:RU365008}; Flags: Fragment;"]
[90850,"'ZNF598'",816,879,989,894.666666666667,{"$nulls":4},"GO:0005871///kinesin complex+++GO:0098978///glutamatergic synapse+++GO:0030424///axon+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0090724///central region of growth cone","GO:0044877///protein-containing complex binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0003723///RNA binding+++GO:0019899///enzyme binding+++GO:0019904///protein domain specific binding+++GO:0046872///metal ion binding+++GO:0043022///ribosome binding+++GO:0016740///transferase activity","GO:0006513///protein monoubiquitination+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0016567///protein ubiquitination+++GO:0006417///regulation of translation+++GO:0072344///rescue of stalled ribosome","zinc finger protein 598","[ZN598_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase ZNF598 {ECO:0000305}; EC=2.3.2.27 {ECO:0000305|PubMed:28065601, ECO:0000305|PubMed:28132843}; AltName: Full=Zinc finger protein 598 {ECO:0000312|HGNC:HGNC:28079};+++[H3BPF3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ZNF598 {ECO:0000313|Ensembl:ENSP00000455292}; Flags: Fragment;+++[H3BQQ2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ZNF598 {ECO:0000313|Ensembl:ENSP00000455882};+++[H3BR87_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ZNF598 {ECO:0000313|Ensembl:ENSP00000456128}; Flags: Fragment;+++[L8E9B0_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF598 {ECO:0000313|EMBL:CCQ43915.1};"]
[9093,"'DNAJA3'",662,703,606,657,"05203///Viral carcinogenesis",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0045202///synapse+++GO:0005829///cytosol+++GO:0019897///extrinsic component of plasma membrane+++GO:0005759///mitochondrial matrix+++GO:0030054///cell junction+++GO:0031594///neuromuscular junction+++GO:0005884///actin filament+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0042645///mitochondrial nucleoid+++GO:0005634///nucleus+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0051059///NF-kappaB binding+++GO:0005524///ATP binding+++GO:0051082///unfolded protein binding+++GO:0044877///protein-containing complex binding+++GO:0030544///Hsp70 protein binding+++GO:0106137///IkappaB kinase complex binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0005133///interferon-gamma receptor binding+++GO:0031072///heat shock protein binding+++GO:0030695///GTPase regulator activity+++GO:0008134///transcription factor binding","GO:0006264///mitochondrial DNA replication+++GO:0007569///cell aging+++GO:0007264///small GTPase mediated signal transduction+++GO:0006924///activation-induced cell death of T cells+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0034341///response to interferon-gamma+++GO:0042102///positive regulation of T cell proliferation+++GO:0006915///apoptotic process+++GO:0033077///T cell differentiation in thymus+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0007005///mitochondrion organization+++GO:0043069///negative regulation of programmed cell death+++GO:0043065///positive regulation of apoptotic process+++GO:0006457///protein folding+++GO:0009408///response to heat+++GO:0006469///negative regulation of protein kinase activity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:0050821///protein stabilization+++GO:0050790///regulation of catalytic activity+++GO:0007528///neuromuscular junction development+++GO:0071340///skeletal muscle acetylcholine-gated channel clustering+++GO:0043066///negative regulation of apoptotic process+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway","DnaJ heat shock protein family (Hsp40) member A3","[DNJA3_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily A member 3, mitochondrial; AltName: Full=DnaJ protein Tid-1; Short=hTid-1; AltName: Full=Hepatocellular carcinoma-associated antigen 57; AltName: Full=Tumorous imaginal discs protein Tid56 homolog; Flags: Precursor;+++[B3KM81_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10471 fis, clone NT2RP2000045, highly similar to DnaJ homolog subfamily A member 3, mitochondrial {ECO:0000313|EMBL:BAG50893.1};+++[I3L1I6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000458868};+++[I3L1T6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000459088}; Flags: Fragment;+++[I3L1T9_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000459098};+++[I3L3D3_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000460358};+++[Q53G26_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily A, member 3 variant {ECO:0000313|EMBL:BAD96825.1}; SubName: Full=DnaJ (Hsp40) homolog, subfamily A, member 3, isoform CRA_b {ECO:0000313|EMBL:EAW85304.1}; Flags: Fragment;+++[Q59E88_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily A, member 3 variant {ECO:0000313|EMBL:BAD93160.1}; Flags: Fragment;"]
[9104,"'RGN'",118,101,89,102.666666666667,"00053///Ascorbate and aldarate metabolism+++00030///Pentose phosphate pathway+++01200///Carbon metabolism+++01220///Degradation of aromatic compounds+++00930///Caprolactam degradation+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++01130///Biosynthesis of antibiotics",null,"M00129///Ascorbate biosynthesis, animals, glucose-1P => ascorbate","R03751///epsilon-Caprolactone lactonohydrolase   epsilon-Caprolactone + H2O <=> 6-Hydroxyhexanoic acid+++R01519///D-Glucono-1,5-lactone lactonohydrolase   D-Glucono-1,5-lactone + H2O <=> D-Gluconic acid+++R02933///L-Gulono-1,4-lactone lactonohydrolase   L-Gulono-1,4-lactone + H2O <=> L-Gulonate","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0004341///gluconolactonase activity+++GO:0030234///enzyme regulator activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0005509///calcium ion binding","GO:0034260///negative regulation of GTPase activity+++GO:1903011///negative regulation of bone development+++GO:0007568///aging+++GO:0006469///negative regulation of protein kinase activity+++GO:1903611///negative regulation of calcium-dependent ATPase activity+++GO:0010907///positive regulation of glucose metabolic process+++GO:2000279///negative regulation of DNA biosynthetic process+++GO:0019853///L-ascorbic acid biosynthetic process+++GO:1901318///negative regulation of flagellated sperm motility+++GO:1901671///positive regulation of superoxide dismutase activity+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0010922///positive regulation of phosphatase activity+++GO:0051344///negative regulation of cyclic-nucleotide phosphodiesterase activity+++GO:1903634///negative regulation of leucine-tRNA ligase activity+++GO:0043547///positive regulation of GTPase activity+++GO:0001822///kidney development+++GO:1901896///positive regulation of calcium-transporting ATPase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0032781///positive regulation of ATPase activity+++GO:1903629///positive regulation of dUTP diphosphatase activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0050848///regulation of calcium-mediated signaling+++GO:0045019///negative regulation of nitric oxide biosynthetic process+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:1902679///negative regulation of RNA biosynthetic process+++GO:0006874///cellular calcium ion homeostasis+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:1903625///negative regulation of DNA catabolic process+++GO:0097421///liver regeneration+++GO:0007283///spermatogenesis+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0001889///liver development+++GO:1903052///positive regulation of proteolysis involved in cellular protein catabolic process","regucalcin","[RGN_HUMAN|Reviewed]RecName: Full=Regucalcin; Short=RC; AltName: Full=Gluconolactonase; Short=GNL; EC=3.1.1.17; AltName: Full=Senescence marker protein 30; Short=SMP-30;+++[V9HWF8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 41 {ECO:0000313|EMBL:ACJ13709.1};"]
[91133,"'L3MBTL4'",98,79,67,81.3333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006325///chromatin organization","L3MBTL4, histone methyl-lysine binding protein","[LMBL4_HUMAN|Reviewed]RecName: Full=Lethal(3)malignant brain tumor-like protein 4; Short=H-l(3)mbt-like protein 4; Short=L(3)mbt-like protein 4; Short=L3mbt-like 4;+++[F8W9S8_HUMAN|Unreviewed]SubName: Full=Lethal(3)malignant brain tumor-like protein 4 {ECO:0000313|Ensembl:ENSP00000318543};+++[J3KRN7_HUMAN|Unreviewed]SubName: Full=Lethal(3)malignant brain tumor-like protein 4 {ECO:0000313|Ensembl:ENSP00000462090}; Flags: Fragment;+++[J3KS41_HUMAN|Unreviewed]SubName: Full=Lethal(3)malignant brain tumor-like protein 4 {ECO:0000313|Ensembl:ENSP00000462295}; Flags: Fragment;+++[J3QLK8_HUMAN|Unreviewed]SubName: Full=Lethal(3)malignant brain tumor-like protein 4 {ECO:0000313|Ensembl:ENSP00000463600}; Flags: Fragment;"]
[9126,"'SMC3'",641,538,466,548.333333333333,"04111///Cell cycle - yeast+++04114///Oocyte meiosis+++04113///Meiosis - yeast+++04110///Cell cycle","H00631///Cornelia de Lange syndrome (CdLS)",null,null,"GO:0000775///chromosome, centromeric region+++GO:0016363///nuclear matrix+++GO:0097431///mitotic spindle pole+++GO:0034991///nuclear meiotic cohesin complex+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000800///lateral element+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0030893///meiotic cohesin complex+++GO:0005622///intracellular+++GO:0005604///basement membrane+++GO:0000785///chromatin","GO:0003777///microtubule motor activity+++GO:0005515///protein binding+++GO:0048487///beta-tubulin binding+++GO:0070840///dynein complex binding+++GO:0003682///chromatin binding+++GO:0036033///mediator complex binding+++GO:0046982///protein heterodimerization activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0007062///sister chromatid cohesion+++GO:0032876///negative regulation of DNA endoreduplication+++GO:1901673///regulation of mitotic spindle assembly+++GO:0006275///regulation of DNA replication+++GO:0000278///mitotic cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0019827///stem cell population maintenance+++GO:0051276///chromosome organization+++GO:0051301///cell division+++GO:0006281///DNA repair+++GO:0051321///meiotic cell cycle+++GO:0007049///cell cycle","structural maintenance of chromosomes 3","[SMC3_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 3; Short=SMC protein 3; Short=SMC-3; AltName: Full=Basement membrane-associated chondroitin proteoglycan; Short=Bamacan; AltName: Full=Chondroitin sulfate proteoglycan 6; AltName: Full=Chromosome-associated polypeptide; Short=hCAP;+++[Q86VX4_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};"]
[9134,"'CCNE2'",0,4,3,2.33333333333333,"04110///Cell cycle+++05161///Hepatitis B+++05206///MicroRNAs in cancer+++04934///Cushing's syndrome+++04151///PI3K-Akt signaling pathway+++04114///Oocyte meiosis+++05200///Pathways in cancer+++05222///Small cell lung cancer+++04391///Hippo signaling pathway - fly+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis+++04218///Cellular senescence+++04115///p53 signaling pathway+++05215///Prostate cancer+++05162///Measles+++05226///Gastric cancer","H00055///Laryngeal cancer+++H00018///Gastric cancer","M00692///Cell cycle - G1/S transition",null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0097135///cyclin E2-CDK2 complex+++GO:0005737///cytoplasm+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005813///centrosome+++GO:0005634///nucleus","GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0004672///protein kinase activity","GO:0070192///chromosome organization involved in meiotic cell cycle+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0051301///cell division+++GO:0051726///regulation of cell cycle+++GO:0007129///synapsis+++GO:0000723///telomere maintenance+++GO:0006270///DNA replication initiation+++GO:0008284///positive regulation of cell proliferation+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division+++GO:1903827///regulation of cellular protein localization+++GO:0000278///mitotic cell cycle+++GO:0045787///positive regulation of cell cycle+++GO:0007049///cell cycle","cyclin E2","[CCNE2_HUMAN|Reviewed]RecName: Full=G1/S-specific cyclin-E2;+++[A0A024R9B0_HUMAN|Unreviewed]SubName: Full=Cyclin E2, isoform CRA_e {ECO:0000313|EMBL:EAW91732.1};+++[E5RHN2_HUMAN|Unreviewed]SubName: Full=G1/S-specific cyclin-E2 {ECO:0000313|Ensembl:ENSP00000430875};+++[E5RK20_HUMAN|Unreviewed]SubName: Full=G1/S-specific cyclin-E2 {ECO:0000313|Ensembl:ENSP00000428988};+++[H0YBQ2_HUMAN|Unreviewed]SubName: Full=G1/S-specific cyclin-E2 {ECO:0000313|Ensembl:ENSP00000430060}; Flags: Fragment;+++[I6L961_HUMAN|Unreviewed]SubName: Full=CCNE2 protein {ECO:0000313|EMBL:AAH07015.1};+++[L8EBC7_HUMAN|Unreviewed]SubName: Full=Alternative protein CCNE2 {ECO:0000313|EMBL:CCQ43813.1};+++[Q8WUE3_HUMAN|Unreviewed]SubName: Full=CCNE2 protein {ECO:0000313|EMBL:AAH20729.1}; SubName: Full=Cyclin E2, isoform CRA_a {ECO:0000313|EMBL:EAW91727.1}; SubName: Full=G1/S-specific cyclin-E2 {ECO:0000313|Ensembl:ENSP00000379437};"]
[9143,"'SYNGR3'",345,371,452,389.333333333333,{"$nulls":4},"GO:0031594///neuromuscular junction+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030672///synaptic vesicle membrane+++GO:0045202///synapse","GO:0042169///SH2 domain binding+++GO:0047485///protein N-terminus binding","GO:0032411///positive regulation of transporter activity+++GO:0045055///regulated exocytosis+++GO:0021762///substantia nigra development","synaptogyrin 3","[SNG3_HUMAN|Reviewed]RecName: Full=Synaptogyrin-3 {ECO:0000305};+++[H3BNA6_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-3 {ECO:0000313|Ensembl:ENSP00000454756}; Flags: Fragment;+++[H3BPJ5_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-3 {ECO:0000313|Ensembl:ENSP00000455344}; Flags: Fragment;+++[H3BQ28_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-3 {ECO:0000313|Ensembl:ENSP00000455577};+++[Q96L30_HUMAN|Unreviewed]SubName: Full=SYNGR3 protein {ECO:0000313|EMBL:AAH09568.1}; SubName: Full=Synaptogyrin-3 {ECO:0000313|Ensembl:ENSP00000481324};"]
[9153,"'SLC28A2'",8.82,7.87,5.03,7.24,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005337///nucleoside transmembrane transporter activity+++GO:0005415///nucleoside:sodium symporter activity+++GO:0015211///purine nucleoside transmembrane transporter activity","GO:1901642///nucleoside transmembrane transport+++GO:0015860///purine nucleoside transmembrane transport+++GO:0006139///nucleobase-containing compound metabolic process","solute carrier family 28 member 2","[S28A2_HUMAN|Reviewed]RecName: Full=Sodium/nucleoside cotransporter 2; AltName: Full=Concentrative nucleoside transporter 2; Short=CNT 2; Short=hCNT2; AltName: Full=Na(+)/nucleoside cotransporter 2; AltName: Full=Sodium-coupled nucleoside transporter 2; AltName: Full=Sodium/purine nucleoside co-transporter; Short=SPNT; AltName: Full=Solute carrier family 28 member 2;+++[H0YNK4_HUMAN|Unreviewed]SubName: Full=Sodium/nucleoside cotransporter 2 {ECO:0000313|Ensembl:ENSP00000454046}; Flags: Fragment;+++[H0YNM6_HUMAN|Unreviewed]SubName: Full=Sodium/nucleoside cotransporter 2 {ECO:0000313|Ensembl:ENSP00000454074}; Flags: Fragment;+++[Q2M2A7_HUMAN|Unreviewed]RecName: Full=Sodium/nucleoside cotransporter {ECO:0000256|RuleBase:RU362018};+++[Q53H72_HUMAN|Unreviewed]RecName: Full=Sodium/nucleoside cotransporter {ECO:0000256|RuleBase:RU362018}; Flags: Fragment;"]
[91646,"'TDRD12'",3,3,2,2.66666666666667,{"$nulls":4},"GO:0005575///cellular_component+++GO:1990923///PET complex","GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003674///molecular_function+++GO:0004386///helicase activity","GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0043046///DNA methylation involved in gamete generation+++GO:0009566///fertilization+++GO:0051321///meiotic cell cycle+++GO:0030154///cell differentiation+++GO:0007275///multicellular organism development","tudor domain containing 12","[TDR12_HUMAN|Reviewed]RecName: Full=Putative ATP-dependent RNA helicase TDRD12; EC=3.6.4.13; AltName: Full=ES cell-associated transcript 8 protein; AltName: Full=Tudor domain-containing protein 12;+++[A0A1B0GU57_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000489971}; Flags: Fragment;+++[A0A1W2PRK2_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000492643}; Flags: Fragment;+++[A0A2R8Y872_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000496698};+++[H3BU70_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000457498}; Flags: Fragment;"]
[9170,"'LPAR2'",225,221,276,240.666666666667,"04072///Phospholipase D signaling pathway+++04810///Regulation of actin cytoskeleton+++04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction+++05200///Pathways in cancer",{"$nulls":3},"GO:0030139///endocytic vesicle+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0009986///cell surface","GO:0070915///lysophosphatidic acid receptor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007202///activation of phospholipase C activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration","lysophosphatidic acid receptor 2","[LPAR2_HUMAN|Reviewed]RecName: Full=Lysophosphatidic acid receptor 2; Short=LPA receptor 2; Short=LPA-2; AltName: Full=Lysophosphatidic acid receptor Edg-4;+++[A0A024R7M9_HUMAN|Unreviewed]SubName: Full=Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4, isoform CRA_a {ECO:0000313|EMBL:EAW84837.1};+++[K7EJJ9_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000465206}; Flags: Fragment;+++[K7ELJ6_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000466112}; Flags: Fragment;+++[K7ENG7_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000466940}; Flags: Fragment;+++[K7ER68_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000468132}; Flags: Fragment;+++[L8E990_HUMAN|Unreviewed]SubName: Full=Alternative protein LPAR2 {ECO:0000313|EMBL:CCQ43276.1};"]
[9181,"'ARHGEF2'",517,607,512,545.333333333333,"05130///Pathogenic Escherichia coli infection+++04530///Tight junction+++05418///Fluid shear stress and atherosclerosis",{"$nulls":3},"GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0014069///postsynaptic density+++GO:0042995///cell projection+++GO:0032587///ruffle membrane+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0031982///vesicle+++GO:0005925///focal adhesion+++GO:0005923///bicellular tight junction+++GO:0005819///spindle+++GO:0002102///podosome+++GO:0043198///dendritic shaft+++GO:0005874///microtubule+++GO:0099092///postsynaptic density, intracellular component+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0017048///Rho GTPase binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0048365///Rac GTPase binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0045087///innate immune response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0000902///cell morphogenesis+++GO:0043065///positive regulation of apoptotic process+++GO:0042127///regulation of cell proliferation+++GO:0035023///regulation of Rho protein signal transduction+++GO:0050768///negative regulation of neurogenesis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0071474///cellular hyperosmotic response+++GO:0030154///cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0045666///positive regulation of neuron differentiation+++GO:0007275///multicellular organism development+++GO:0006886///intracellular protein transport+++GO:1902219///negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:2001224///positive regulation of neuron migration+++GO:0071225///cellular response to muramyl dipeptide+++GO:0002376///immune system process+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0071802///negative regulation of podosome assembly+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0000132///establishment of mitotic spindle orientation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071356///cellular response to tumor necrosis factor+++GO:0060546///negative regulation of necroptotic process+++GO:0007015///actin filament organization+++GO:0007049///cell cycle+++GO:0055059///asymmetric neuroblast division+++GO:0051301///cell division+++GO:0007186///G protein-coupled receptor signaling pathway","Rho/Rac guanine nucleotide exchange factor 2","[ARHG2_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 2; AltName: Full=Guanine nucleotide exchange factor H1; Short=GEF-H1; AltName: Full=Microtubule-regulated Rho-GEF; AltName: Full=Proliferating cell nucleolar antigen p40;+++[A0A1Y8EN19_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000476518}; Flags: Fragment;+++[D3DVA5_HUMAN|Unreviewed]SubName: Full=Rho/rac guanine nucleotide exchange factor (GEF) 2, isoform CRA_a {ECO:0000313|EMBL:EAW53017.1};+++[Q5VY93_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000357298};+++[V9GY94_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000476532}; Flags: Fragment;+++[V9GYF0_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000476689}; Flags: Fragment;+++[V9GYF5_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000476699}; Flags: Fragment;+++[V9GYG5_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000476724}; Flags: Fragment;+++[V9GYM8_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000476916};+++[V9GZ14_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000477299}; Flags: Fragment;+++[V9GZ58_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 2 {ECO:0000313|Ensembl:ENSP00000477448}; Flags: Fragment;"]
[91893,"'FDXACB1'",35,21,20,25.3333333333333,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0070042///rRNA (uridine-N3-)-methyltransferase activity","GO:0070475///rRNA base methylation","ferredoxin-fold anticodon binding domain containing 1","[FDXA1_HUMAN|Reviewed]RecName: Full=Ferredoxin-fold anticodon-binding domain-containing protein 1; Short=FDX-ACDB domain-containing protein 1;+++[B3KUL3_HUMAN|Unreviewed]SubName: Full=Ferredoxin-fold anticodon-binding domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000435572}; SubName: Full=cDNA FLJ40164 fis, clone TESTI2015914 {ECO:0000313|EMBL:BAG53475.1}; Flags: Fragment;+++[E9PK62_HUMAN|Unreviewed]SubName: Full=Ferredoxin-fold anticodon-binding domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000431629};"]
[92014,"'SLC25A51'",82,109.97,72,87.99,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport","solute carrier family 25 member 51","[S2551_HUMAN|Reviewed]RecName: Full=Solute carrier family 25 member 51; AltName: Full=Mitochondrial carrier triple repeat protein 1;+++[D3DRQ4_HUMAN|Unreviewed]SubName: Full=Mitochondrial carrier triple repeat 1, isoform CRA_a {ECO:0000313|EMBL:EAW58260.1};"]
[92126,"'DSEL'",398,365,354,372.333333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane","GO:0047757///chondroitin-glucuronate 5-epimerase activity+++GO:0008146///sulfotransferase activity+++GO:0016853///isomerase activity","GO:0030204///chondroitin sulfate metabolic process+++GO:0030205///dermatan sulfate metabolic process+++GO:0030208///dermatan sulfate biosynthetic process","dermatan sulfate epimerase like","[DSEL_HUMAN|Reviewed]RecName: Full=Dermatan-sulfate epimerase-like protein; EC=5.1.-.-; Flags: Precursor;"]
[92259,"'MRPS36'",81,67,86,78,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0009353///mitochondrial oxoglutarate dehydrogenase complex+++GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005763///mitochondrial small ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0004591///oxoglutarate dehydrogenase (succinyl-transferring) activity","GO:0006103///2-oxoglutarate metabolic process+++GO:0006412///translation+++GO:0070125///mitochondrial translational elongation+++GO:0055114///oxidation-reduction process+++GO:0070126///mitochondrial translational termination","mitochondrial ribosomal protein S36","[RT36_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S36, mitochondrial; Short=MRP-S36; Short=S36mt;+++[D6R941_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S36, mitochondrial {ECO:0000313|Ensembl:ENSP00000423659};"]
[92304,"'SCGB3A1'",32,12,19,21,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome","GO:0005125///cytokine activity","GO:1901741///positive regulation of myoblast fusion+++GO:0030308///negative regulation of cell growth+++GO:0010469///regulation of signaling receptor activity+++GO:0042127///regulation of cell proliferation","secretoglobin family 3A member 1","[SG3A1_HUMAN|Reviewed]RecName: Full=Secretoglobin family 3A member 1; AltName: Full=Cytokine HIN-1; AltName: Full=High in normal 1; AltName: Full=Pneumo secretory protein 2; Short=PnSP-2; AltName: Full=Uteroglobin-related protein 2; Flags: Precursor;"]
[92340,"'PRR29'",19,20,27,22,"04514///Cell adhesion molecules (CAMs)+++04650///Natural killer cell mediated cytotoxicity",{"$nulls":3},"GO:0001931///uropod+++GO:0016020///membrane+++GO:0005902///microvillus+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0032154///cleavage furrow","GO:0005178///integrin binding","GO:0007155///cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0098609///cell-cell adhesion+++GO:0050776///regulation of immune response+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","proline rich 29","[PRR29_HUMAN|Reviewed]RecName: Full=Proline-rich protein 29;+++[B4DG13_HUMAN|Unreviewed]SubName: Full=HCG1657684, isoform CRA_c {ECO:0000313|EMBL:EAW94223.1}; SubName: Full=cDNA FLJ52641 {ECO:0000313|EMBL:BAG57624.1};+++[J3KRF4_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 29 {ECO:0000313|Ensembl:ENSP00000461973};+++[J3KRR4_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 29 {ECO:0000313|Ensembl:ENSP00000462130}; Flags: Fragment;+++[J3QR92_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 29 {ECO:0000313|Ensembl:ENSP00000464103};"]
[9254,"'CACNA2D2'",121,180,141,147.333333333333,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04261///Adrenergic signaling in cardiomyocytes+++04010///MAPK signaling pathway+++04260///Cardiac muscle contraction+++05410///Hypertrophic cardiomyopathy (HCM)+++04921///Oxytocin signaling pathway+++05414///Dilated cardiomyopathy (DCM)",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005891///voltage-gated calcium channel complex","GO:0005262///calcium channel activity+++GO:0046872///metal ion binding+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity","GO:0046622///positive regulation of organ growth+++GO:0070588///calcium ion transmembrane transport+++GO:0040014///regulation of multicellular organism growth+++GO:0034765///regulation of ion transmembrane transport+++GO:0060024///rhythmic synaptic transmission+++GO:0048747///muscle fiber development+++GO:0006816///calcium ion transport+++GO:0050796///regulation of insulin secretion+++GO:0006811///ion transport+++GO:0007528///neuromuscular junction development","calcium voltage-gated channel auxiliary subunit alpha2delta 2","[CA2D2_HUMAN|Reviewed]RecName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-2; AltName: Full=Voltage-gated calcium channel subunit alpha-2/delta-2; Contains: RecName: Full=Voltage-dependent calcium channel subunit alpha-2-2; Contains: RecName: Full=Voltage-dependent calcium channel subunit delta-2; Flags: Precursor;+++[C9JE82_HUMAN|Unreviewed]SubName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-2 {ECO:0000313|Ensembl:ENSP00000404631};+++[C9JVC9_HUMAN|Unreviewed]SubName: Full=Voltage-dependent calcium channel subunit alpha-2/delta-2 {ECO:0000313|Ensembl:ENSP00000407393};+++[L0R6E1_HUMAN|Unreviewed]SubName: Full=Alternative protein CACNA2D2 {ECO:0000313|EMBL:CCO13697.1};"]
[92591,"'ASB16'",4,2,3,3,{"$nulls":4},"GO:0005829///cytosol","GO:0005515///protein binding","GO:0035556///intracellular signal transduction+++GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination","ankyrin repeat and SOCS box containing 16","[ASB16_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 16; Short=ASB-16;+++[K7ELE0_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 16 {ECO:0000313|Ensembl:ENSP00000466033};+++[K7EM41_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box protein 16 {ECO:0000313|Ensembl:ENSP00000466349}; Flags: Fragment;+++[Q147X6_HUMAN|Unreviewed]SubName: Full=ASB16 protein {ECO:0000313|EMBL:AAI18586.1}; SubName: Full=Ankyrin repeat and SOCS box-containing 16, isoform CRA_b {ECO:0000313|EMBL:EAW51628.1};+++[Q6Q622_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and SOCS box-containing protein 16 isoform {ECO:0000313|EMBL:AAS67920.1};"]
[9275,"'BCL7B'",910,993,1100,1001,{"$nulls":4},"GO:0005575///cellular_component","GO:0005515///protein binding+++GO:0003779///actin binding","GO:0006915///apoptotic process+++GO:0016055///Wnt signaling pathway+++GO:0008150///biological_process+++GO:0030154///cell differentiation","BCL tumor suppressor 7B","[BCL7B_HUMAN|Reviewed]RecName: Full=B-cell CLL/lymphoma 7 protein family member B; AltName: Allergen=Hom s 3;+++[F2Z3H6_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member B {ECO:0000313|Ensembl:ENSP00000411073}; SubName: Full=B-cell CLL/lymphoma 7B, isoform CRA_a {ECO:0000313|EMBL:EAW69675.1};+++[F8WDZ4_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member B {ECO:0000313|Ensembl:ENSP00000414473};+++[F8WE18_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member B {ECO:0000313|Ensembl:ENSP00000414231};"]
[92815,"'HIST3H2A'",98,75,92,88.3333333333333,"05322///Systemic lupus erythematosus+++05034///Alcoholism+++04217///Necroptosis",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0070062///extracellular exosome+++GO:0000788///nuclear nucleosome+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006325///chromatin organization+++GO:0006337///nucleosome disassembly+++GO:0070914///UV-damage excision repair","histone cluster 3 H2A","[H2A3_HUMAN|Reviewed]RecName: Full=Histone H2A type 3;"]
[93058,"'COQ10A'",203,180,172,185,"01100///Metabolic pathways+++01200///Carbon metabolism+++00020///Citrate cycle (TCA cycle)+++01230///Biosynthesis of amino acids+++01120///Microbial metabolism in diverse environments+++01130///Biosynthesis of antibiotics+++00630///Glyoxylate and dicarboxylate metabolism+++01210///2-Oxocarboxylic acid metabolism+++01110///Biosynthesis of secondary metabolites",null,"M00740///Methylaspartate cycle+++M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00010///Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate+++M00012///Glyoxylate cycle","R00351///acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing) Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate","GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0048039///ubiquinone binding","GO:0045333///cellular respiration+++GO:0006744///ubiquinone biosynthetic process","coenzyme Q10A","[CQ10A_HUMAN|Reviewed]RecName: Full=Coenzyme Q-binding protein COQ10 homolog A, mitochondrial; Flags: Precursor;+++[H0YHF1_HUMAN|Unreviewed]SubName: Full=Coenzyme Q-binding protein COQ10 homolog A, mitochondrial {ECO:0000313|Ensembl:ENSP00000446957}; Flags: Fragment;+++[H0YHW3_HUMAN|Unreviewed]SubName: Full=Coenzyme Q-binding protein COQ10 homolog A, mitochondrial {ECO:0000313|Ensembl:ENSP00000447964}; Flags: Fragment;"]
[93109,"'TMEM44'",70,106.11,100,92.0366666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:1903826///arginine transmembrane transport+++GO:1903401///L-lysine transmembrane transport","transmembrane protein 44","[TMM44_HUMAN|Reviewed]RecName: Full=Transmembrane protein 44;+++[C9IZ85_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 44 {ECO:0000313|Ensembl:ENSP00000328300};+++[F8WCY1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 44 {ECO:0000313|Ensembl:ENSP00000390186};+++[F8WE47_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 44 {ECO:0000313|Ensembl:ENSP00000414077};+++[H7C3X7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 44 {ECO:0000313|Ensembl:ENSP00000414333}; Flags: Fragment;+++[J3KQW3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 44 {ECO:0000313|Ensembl:ENSP00000409963}; Flags: Fragment;+++[Q6PL43_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 44 {ECO:0000313|Ensembl:ENSP00000403053};+++[Q96I73_HUMAN|Unreviewed]SubName: Full=TMEM44 protein {ECO:0000313|EMBL:AAH07772.2};"]
[9326,"'ZNHIT3'",120,101,154,125,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005622///intracellular+++GO:0070761///pre-snoRNP complex","GO:0046966///thyroid hormone receptor binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0048254///snoRNA localization+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000492///box C/D snoRNP assembly","zinc finger HIT-type containing 3","[ZNHI3_HUMAN|Reviewed]RecName: Full=Zinc finger HIT domain-containing protein 3; AltName: Full=HNF-4a coactivator; AltName: Full=Thyroid hormone receptor interactor 3; AltName: Full=Thyroid receptor-interacting protein 3; Short=TR-interacting protein 3; Short=TRIP-3;+++[A0A024R0X8_HUMAN|Unreviewed]SubName: Full=Zinc finger, HIT type 3, isoform CRA_a {ECO:0000313|EMBL:EAW57554.1};+++[A0A087WTR0_HUMAN|Unreviewed]SubName: Full=Zinc finger HIT domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000478067};+++[A0A087WY42_HUMAN|Unreviewed]SubName: Full=Zinc finger HIT domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000481499};+++[A0A087WY54_HUMAN|Unreviewed]SubName: Full=Zinc finger HIT domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000481522}; Flags: Fragment;+++[A0A087WYI8_HUMAN|Unreviewed]SubName: Full=Zinc finger HIT domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000481843}; Flags: Fragment;+++[A0A087X045_HUMAN|Unreviewed]SubName: Full=Zinc finger HIT domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000483088};+++[A0A087X1G0_HUMAN|Unreviewed]SubName: Full=Zinc finger HIT domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000484178}; Flags: Fragment;"]
[93349,"'SP140L'",106.62,143.93,166.6,139.05,"05203///Viral carcinogenesis+++05168///Herpes simplex infection",{"$nulls":3},"GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II","SP140 nuclear body protein like","[SP14L_HUMAN|Reviewed]RecName: Full=Nuclear body protein SP140-like protein;+++[H7BYP4_HUMAN|Unreviewed]SubName: Full=Nuclear body protein SP140-like protein {ECO:0000313|Ensembl:ENSP00000379811}; SubName: Full=SP140L-2 protein {ECO:0000313|EMBL:AGZ83103.1};+++[U5Y1J8_HUMAN|Unreviewed]SubName: Full=SP140L-3 protein {ECO:0000313|EMBL:AGZ83104.1};+++[U5Y3L1_HUMAN|Unreviewed]SubName: Full=Nuclear body protein SP140-like protein {ECO:0000313|Ensembl:ENSP00000243810}; SubName: Full=SP140L-1 protein {ECO:0000313|EMBL:AGZ83102.1};"]
[9355,"'LHX2'",5672,5477,5566,5571.66666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding","GO:0021978///telencephalon regionalization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001942///hair follicle development+++GO:0009953///dorsal/ventral pattern formation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0022008///neurogenesis+++GO:0060041///retina development in camera-type eye+++GO:0021537///telencephalon development+++GO:0007411///axon guidance+++GO:0007498///mesoderm development+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007420///brain development+++GO:0001843///neural tube closure+++GO:0007399///nervous system development+++GO:0021987///cerebral cortex development+++GO:0048675///axon extension+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0021772///olfactory bulb development+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:0030182///neuron differentiation+++GO:0045814///negative regulation of gene expression, epigenetic","LIM homeobox 2","[LHX2_HUMAN|Reviewed]RecName: Full=LIM/homeobox protein Lhx2; Short=Homeobox protein LH-2; Short=LIM homeobox protein 2;+++[B3KNJ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14691 fis, clone NT2RP2005325, highly similar to LIM/homeobox protein Lhx2 {ECO:0000313|EMBL:BAG51357.1};+++[H0YM35_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000453448}; Flags: Fragment;+++[H7C0H1_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000394978}; Flags: Fragment;+++[U3KQT5_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000476200}; Flags: Fragment;"]
[93627,"'TBCK'",473.85,437.9,443.04,451.596666666667,null,"H01922///Infantile hypotonia with psychomotor retardation and characteristic facies",null,null,"GO:0005856///cytoskeleton+++GO:0072686///mitotic spindle+++GO:0005819///spindle+++GO:0005737///cytoplasm+++GO:0030496///midbody","GO:0017137///Rab GTPase binding+++GO:0005524///ATP binding+++GO:0005096///GTPase activator activity+++GO:0004672///protein kinase activity","GO:0008283///cell proliferation+++GO:0032006///regulation of TOR signaling+++GO:0030036///actin cytoskeleton organization+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity+++GO:0006468///protein phosphorylation","TBC1 domain containing kinase","[TBCK_HUMAN|Reviewed]RecName: Full=TBC domain-containing protein kinase-like protein;+++[A0A024RDH3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX06202.1};+++[D6R950_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000423637}; Flags: Fragment;+++[D6RC61_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000423834}; Flags: Fragment;+++[D6RDG2_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000420985}; Flags: Fragment;+++[D6RDY5_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000425197}; Flags: Fragment;+++[H0Y8U7_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000422160}; Flags: Fragment;+++[H0Y959_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000423092}; Flags: Fragment;+++[H0YA45_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000426093}; Flags: Fragment;+++[Q5HYF5_HUMAN|Unreviewed]SubName: Full=TBC domain-containing protein kinase-like protein {ECO:0000313|Ensembl:ENSP00000421182};"]
[9375,"'TM9SF2'",3251,3489,3262,3334,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0010008///endosome membrane+++GO:0005768///endosome",null,"GO:0072657///protein localization to membrane","transmembrane 9 superfamily member 2","[TM9S2_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 2; AltName: Full=p76; Flags: Precursor;+++[A0A024QYR8_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[A0A2R8Y4S7_HUMAN|Unreviewed]SubName: Full=Transmembrane 9 superfamily member 2 {ECO:0000313|Ensembl:ENSP00000494275}; Flags: Fragment;"]
[93979,"'CPA5'",1,5,3,3,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008237///metallopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008233///peptidase activity","GO:0006508///proteolysis","carboxypeptidase A5","[CBPA5_HUMAN|Reviewed]RecName: Full=Carboxypeptidase A5; EC=3.4.17.-; Flags: Precursor;+++[A0A1D5RMQ7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000419013}; Flags: Fragment;+++[A4D1M2_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|EMBL:EAL24090.1}; SubName: Full=Carboxypeptidase A5, isoform CRA_a {ECO:0000313|EMBL:EAW83754.1}; SubName: Full=Testicular tissue protein Li 32 {ECO:0000313|EMBL:AEE60945.1};+++[B2RCS8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ96260, highly similar to Homo sapiens carboxypeptidase A5 (CPA5), mRNA {ECO:0000313|EMBL:BAG37675.1};+++[C9JRV5_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000420060}; Flags: Fragment;+++[C9JZE9_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000419778}; Flags: Fragment;+++[H7C4Q6_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000417886}; Flags: Fragment;"]
[94032,"'CAMK2N2'",65,87,82,78,{"$nulls":4},"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004860///protein kinase inhibitor activity+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0019901///protein kinase binding","GO:0006469///negative regulation of protein kinase activity","calcium/calmodulin dependent protein kinase II inhibitor 2","[CK2N2_HUMAN|Reviewed]RecName: Full=Calcium/calmodulin-dependent protein kinase II inhibitor 2; AltName: Full=CaM-KII inhibitory protein; Short=CaM-KIIN;"]
[94056,"'SYAP1'",605,604,612,607,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030425///dendrite+++GO:0042734///presynaptic membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030424///axon+++GO:0030054///cell junction+++GO:0045211///postsynaptic membrane+++GO:0030426///growth cone+++GO:0005794///Golgi apparatus+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0005634///nucleus+++GO:0043204///perikaryon+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:1990314///cellular response to insulin-like growth factor stimulus+++GO:0090073///positive regulation of protein homodimerization activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0036120///cellular response to platelet-derived growth factor stimulus+++GO:0032869///cellular response to insulin stimulus+++GO:0030154///cell differentiation+++GO:0038203///TORC2 signaling+++GO:0045600///positive regulation of fat cell differentiation","synapse associated protein 1","[SYAP1_HUMAN|Reviewed]RecName: Full=Synapse-associated protein 1 {ECO:0000305}; AltName: Full=BSD domain-containing signal transducer and Akt interactor protein {ECO:0000303|PubMed:23300339}; Short=BSTA {ECO:0000303|PubMed:23300339};"]
[9423,"'NTN1'",727,366,510,534.333333333333,"04360///Axon guidance",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005604///basement membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0008284///positive regulation of cell proliferation+++GO:0030517///negative regulation of axon extension+++GO:0032488///Cdc42 protein signal transduction+++GO:0007411///axon guidance+++GO:0060603///mammary gland duct morphogenesis+++GO:0042472///inner ear morphogenesis+++GO:0030879///mammary gland development+++GO:0030334///regulation of cell migration+++GO:0007097///nuclear migration+++GO:0033564///anterior/posterior axon guidance+++GO:0098609///cell-cell adhesion+++GO:2000147///positive regulation of cell motility+++GO:0051963///regulation of synapse assembly+++GO:0006930///substrate-dependent cell migration, cell extension+++GO:0007265///Ras protein signal transduction+++GO:0001764///neuron migration+++GO:0006915///apoptotic process+++GO:0045773///positive regulation of axon extension+++GO:1902842///negative regulation of netrin-activated signaling pathway+++GO:0007409///axonogenesis","netrin 1","[NET1_HUMAN|Reviewed]RecName: Full=Netrin-1; AltName: Full=Epididymis tissue protein Li 131P; Flags: Precursor;+++[H7BZF4_HUMAN|Unreviewed]SubName: Full=Netrin-1 {ECO:0000313|Ensembl:ENSP00000389375}; Flags: Fragment;"]
[94235,"'GNG8'",0,0,2,0.666666666666667,"05034///Alcoholism+++04151///PI3K-Akt signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04062///Chemokine signaling pathway+++04926///Relaxin signaling pathway+++04728///Dopaminergic synapse+++04725///Cholinergic synapse+++04723///Retrograde endocannabinoid signaling+++04713///Circadian entrainment+++05200///Pathways in cancer+++04726///Serotonergic synapse+++05163///Human cytomegalovirus infection+++04371///Apelin signaling pathway+++04727///GABAergic synapse+++04014///Ras signaling pathway+++04724///Glutamatergic synapse+++05032///Morphine addiction",{"$nulls":3},"GO:0005834///heterotrimeric G-protein complex+++GO:0005886///plasma membrane","GO:0003924///GTPase activity","GO:0043584///nose development+++GO:0035176///social behavior+++GO:0007399///nervous system development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071444///cellular response to pheromone","G protein subunit gamma 8","[GBG8_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8; AltName: Full=Gamma-9; Flags: Precursor;"]
[9443,"'MED7'",72,50,91,71,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0016592///mediator complex+++GO:0016604///nuclear body+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003712///transcription coregulator activity+++GO:0061630///ubiquitin protein ligase activity","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0019827///stem cell population maintenance+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016567///protein ubiquitination","mediator complex subunit 7","[MED7_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 7; Short=hMED7; AltName: Full=Activator-recruited cofactor 34 kDa component; Short=ARC34; AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 9; Short=CRSP complex subunit 9; AltName: Full=Mediator complex subunit 7; AltName: Full=RNA polymerase transcriptional regulation mediator subunit 7 homolog; AltName: Full=Transcriptional coactivator CRSP33;+++[E5RIE8_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|RuleBase:RU364060}; Flags: Fragment;+++[Q6IAZ5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 7 {ECO:0000256|RuleBase:RU364060};"]
[9465,"'AKAP7'",87,72,100,86.3333333333333,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0098686///hippocampal mossy fiber to CA3 synapse","GO:0000166///nucleotide binding+++GO:0019901///protein kinase binding+++GO:0051018///protein kinase A binding+++GO:0005515///protein binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0016301///kinase activity","GO:0010738///regulation of protein kinase A signaling+++GO:1902261///positive regulation of delayed rectifier potassium channel activity+++GO:0071320///cellular response to cAMP+++GO:0008104///protein localization+++GO:0008150///biological_process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0060306///regulation of membrane repolarization+++GO:0001508///action potential+++GO:0006811///ion transport+++GO:0035556///intracellular signal transduction+++GO:0016310///phosphorylation+++GO:1901381///positive regulation of potassium ion transmembrane transport","A-kinase anchoring protein 7","[AKA7A_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 7 isoforms alpha and beta; Short=AKAP-7 isoforms alpha and beta; AltName: Full=A-kinase anchor protein 18 kDa; Short=AKAP 18; AltName: Full=Protein kinase A-anchoring protein 7 isoforms alpha/beta; Short=PRKA7 isoforms alpha/beta;+++[AKA7G_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 7 isoform gamma; Short=AKAP-7 isoform gamma; AltName: Full=A-kinase anchor protein 18 kDa; Short=AKAP 18; AltName: Full=Protein kinase A-anchoring protein 7 isoform gamma; Short=PRKA7 isoform gamma;+++[F5GXD1_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000441048};+++[F5H4P9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000446022};+++[H0YH01_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000445486}; Flags: Fragment;+++[J3KN37_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 7 isoform gamma {ECO:0000313|Ensembl:ENSP00000263050};+++[Q2TAJ5_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein 7 {ECO:0000313|EMBL:AAI10898.1}; SubName: Full=A kinase (PRKA) anchor protein 7, isoform CRA_c {ECO:0000313|EMBL:EAW48059.1}; SubName: Full=A-kinase anchor protein 7 isoform alpha {ECO:0000313|EMBL:BAG70087.1}; SubName: Full=cDNA, FLJ92081, Homo sapiens A kinase (PRKA) anchor protein 7 (AKAP7), transcriptvariant alpha, mRNA {ECO:0000313|EMBL:BAG34762.1};+++[Q6P4D3_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein 7 {ECO:0000313|EMBL:AAH63499.1};"]
[9481,"'SLC25A27'",47,42,35,41.3333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0043025///neuronal cell body","GO:0022857///transmembrane transporter activity","GO:0035356///cellular triglyceride homeostasis+++GO:0070997///neuron death+++GO:0048839///inner ear development+++GO:0008284///positive regulation of cell proliferation+++GO:0051562///negative regulation of mitochondrial calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0043066///negative regulation of apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0046324///regulation of glucose import+++GO:0009409///response to cold+++GO:1902600///proton transmembrane transport","solute carrier family 25 member 27","[UCP4_HUMAN|Reviewed]RecName: Full=Mitochondrial uncoupling protein 4; Short=UCP 4; AltName: Full=Solute carrier family 25 member 27;+++[B4DHR4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25, member 27, isoform CRA_a {ECO:0000313|EMBL:EAX04298.1}; SubName: Full=cDNA FLJ57819, highly similar to Mitochondrial uncoupling protein 4 {ECO:0000313|EMBL:BAG58226.1}; SubName: Full=cDNA, FLJ78839, highly similar to Mitochondrial uncoupling protein 4 {ECO:0000313|EMBL:BAH14311.1};+++[Q5VTS8_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 4 {ECO:0000313|Ensembl:ENSP00000474781}; Flags: Fragment;+++[S4R300_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 4 {ECO:0000313|Ensembl:ENSP00000473804}; Flags: Fragment;+++[S4R3J2_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 4 {ECO:0000313|Ensembl:ENSP00000474429}; Flags: Fragment;"]
[9501,"'RPH3AL'",12,19,25.86,18.9533333333333,{"$nulls":4},"GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005623///cell","GO:0030274///LIM domain binding+++GO:0017137///Rab GTPase binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding","GO:0017157///regulation of exocytosis+++GO:0042593///glucose homeostasis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0042493///response to drug+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis","rabphilin 3A like (without C2 domains)","[RPH3L_HUMAN|Reviewed]RecName: Full=Rab effector Noc2; AltName: Full=No C2 domains protein; AltName: Full=Rabphilin-3A-like protein;+++[A0A0J9YWA6_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000487877}; Flags: Fragment;+++[A0A0J9YX72_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000488277}; Flags: Fragment;+++[A8K7D5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77349, highly similar to Homo sapiens rabphilin 3A-like (without C2 domains), mRNA {ECO:0000313|EMBL:BAF84639.1};+++[I3L181_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000458643}; Flags: Fragment;+++[I3L1Q0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459001}; Flags: Fragment;+++[I3L2G8_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459666}; Flags: Fragment;+++[I3L2I9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459716}; Flags: Fragment;+++[I3L2N0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459795}; Flags: Fragment;+++[I3L2W0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459975}; Flags: Fragment;+++[I3L2X0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459992}; Flags: Fragment;+++[I3L308_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460080}; Flags: Fragment;+++[I3L349_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460171}; Flags: Fragment;+++[I3L3M9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460580}; Flags: Fragment;+++[I3NI49_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000461885}; Flags: Fragment;"]
[9524,"'TECR'",4187,4707,5265,4719.66666666667,"01212///Fatty acid metabolism+++01040///Biosynthesis of unsaturated fatty acids+++00062///Fatty acid elongation+++01110///Biosynthesis of secondary metabolites","H00768///Nonsyndromic autosomal recessive mental retardation (NS-ARMR)","M00415///Fatty acid biosynthesis, elongation, endoplasmic reticulum","R09449///very-long-chain acyl-CoA:NADP+ oxidoreductase   trans-2,3-Dehydroacyl-CoA + NADPH + H+ <=> Long-chain acyl-CoA + NADP++++R07761///octadecanoyl-CoA:NADP+ trans-2-oxidoreductase   (2E)-Octadecenoyl-CoA + NADPH + H+ <=> Stearoyl-CoA + NADP++++R10828///very-long-chain acyl-CoA:NADP+ oxidoreductase   Very-long-chain acyl-CoA + NADP+ <=> Very-long-chain trans-2,3-dehydroacyl-CoA + NADPH + H+","GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0102758///very-long-chain enoyl-CoA reductase activity+++GO:0017099///very-long-chain-acyl-CoA dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors","GO:0055114///oxidation-reduction process+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0006633///fatty acid biosynthetic process+++GO:0030497///fatty acid elongation+++GO:0006631///fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0042761///very long-chain fatty acid biosynthetic process","trans-2,3-enoyl-CoA reductase","[TECR_HUMAN|Reviewed]RecName: Full=Very-long-chain enoyl-CoA reductase {ECO:0000305}; EC=1.3.1.93 {ECO:0000269|PubMed:12482854}; AltName: Full=Synaptic glycoprotein SC2; AltName: Full=Trans-2,3-enoyl-CoA reductase; Short=TER;+++[B3KSQ1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36768 fis, clone ADIPS1000064, highly similar to Synaptic glycoprotein SC2 {ECO:0000313|EMBL:BAG52813.1};+++[M0R2E5_HUMAN|Unreviewed]SubName: Full=Very-long-chain enoyl-CoA reductase {ECO:0000313|Ensembl:ENSP00000472504};+++[M0R2N5_HUMAN|Unreviewed]SubName: Full=Very-long-chain enoyl-CoA reductase {ECO:0000313|Ensembl:ENSP00000472697};+++[M0R329_HUMAN|Unreviewed]SubName: Full=Very-long-chain enoyl-CoA reductase {ECO:0000313|Ensembl:ENSP00000472957}; Flags: Fragment;+++[M0R3C3_HUMAN|Unreviewed]SubName: Full=Very-long-chain enoyl-CoA reductase {ECO:0000313|Ensembl:ENSP00000473129};"]
[9537,"'TP53I11'",1427,1554,1564,1515,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:0008285///negative regulation of cell proliferation","tumor protein p53 inducible protein 11","[P5I11_HUMAN|Reviewed]RecName: Full=Tumor protein p53-inducible protein 11; AltName: Full=p53-induced gene 11 protein;+++[E9PIK4_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000435800};+++[E9PIN5_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000435739}; Flags: Fragment;+++[E9PKN9_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000431556}; Flags: Fragment;+++[E9PKZ4_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000433454}; Flags: Fragment;+++[E9PMW4_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000437284}; Flags: Fragment;+++[E9PMY0_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000437258}; Flags: Fragment;+++[E9PN66_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000432926}; Flags: Fragment;+++[E9PNB3_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000437243};+++[E9PPM1_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000346564};+++[E9PQ46_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000434461}; Flags: Fragment;+++[E9PS55_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000432089}; Flags: Fragment;+++[Q8N8U5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38857 fis, clone MESAN2011597 {ECO:0000313|EMBL:BAC04717.1};+++[U3KQ32_HUMAN|Unreviewed]SubName: Full=Tumor protein p53-inducible protein 11 {ECO:0000313|Ensembl:ENSP00000475501};"]
[9559,"'VPS26A'",502,476,477,485,"04144///Endocytosis",{"$nulls":3},"GO:0005769///early endosome+++GO:0097422///tubular endosome+++GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0030906///retromer, cargo-selective complex+++GO:0030904///retromer complex+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0031982///vesicle+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0008565///protein transporter activity","GO:0016055///Wnt signaling pathway+++GO:0015031///protein transport+++GO:0016241///regulation of macroautophagy+++GO:0006886///intracellular protein transport+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0042147///retrograde transport, endosome to Golgi","VPS26, retromer complex component A","[VP26A_HUMAN|Reviewed]RecName: Full=Vacuolar protein sorting-associated protein 26A; AltName: Full=Vesicle protein sorting 26A; Short=hVPS26;+++[B4DLT1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59716, highly similar to Vacuolar protein sorting 26A {ECO:0000313|EMBL:BAG59643.1};+++[S4R2Y3_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 26A {ECO:0000313|Ensembl:ENSP00000473746};+++[S4R3Q6_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 26A {ECO:0000313|Ensembl:ENSP00000474611};"]
[9576,"'SPAG6'",13,2,1,5.33333333333333,{"$nulls":4},"GO:0042995///cell projection+++GO:0015630///microtubule cytoskeleton+++GO:0005929///cilium+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0031514///motile cilium+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005930///axoneme","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0030030///cell projection organization+++GO:0007286///spermatid development","sperm associated antigen 6","[SPAG6_HUMAN|Reviewed]RecName: Full=Sperm-associated antigen 6; AltName: Full=Protein PF16 homolog; AltName: Full=Repro-SA-1; AltName: Full=Sperm flagellar protein;+++[A0A0A0MRT8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 6 {ECO:0000313|Ensembl:ENSP00000365788};+++[A0A0A0MSY0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 6 {ECO:0000313|Ensembl:ENSP00000406594}; Flags: Fragment;+++[A0A0A0MT17_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 6 {ECO:0000313|Ensembl:ENSP00000411111}; Flags: Fragment;+++[A0A140VJU9_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 176 {ECO:0000313|EMBL:AEE61086.1};+++[E0ZS56_HUMAN|Unreviewed]SubName: Full=Sperm associated antigen 6 {ECO:0000313|EMBL:ADM86748.1}; Flags: Fragment;"]
[9603,"'NFE2L3'",427,479,534,480,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II","nuclear factor, erythroid 2 like 3","[NF2L3_HUMAN|Reviewed]RecName: Full=Nuclear factor erythroid 2-related factor 3; Short=NF-E2-related factor 3; Short=NFE2-related factor 3; AltName: Full=Nuclear factor, erythroid derived 2, like 3;+++[A4D178_HUMAN|Unreviewed]SubName: Full=Nuclear factor (Erythroid-derived 2)-like 3 {ECO:0000313|EMBL:EAL24236.1};+++[U3KQ19_HUMAN|Unreviewed]SubName: Full=Nuclear factor erythroid 2-related factor 3 {ECO:0000313|Ensembl:ENSP00000475463}; Flags: Fragment;"]
[9619,"'ABCG1'",746,455,487,562.666666666667,"02010///ABC transporters",{"$nulls":3},"GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0000139///Golgi membrane+++GO:0005623///cell","GO:0043531///ADP binding+++GO:0005548///phospholipid transporter activity+++GO:0046983///protein dimerization activity+++GO:0000166///nucleotide binding+++GO:0005543///phospholipid binding+++GO:0019534///toxin transmembrane transporter activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0042803///protein homodimerization activity+++GO:0015485///cholesterol binding+++GO:0016887///ATPase activity+++GO:0017127///cholesterol transporter activity+++GO:0034437///glycoprotein transporter activity+++GO:0034041///sterol-transporting ATPase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0046982///protein heterodimerization activity","GO:1901998///toxin transport+++GO:0033700///phospholipid efflux+++GO:0010887///negative regulation of cholesterol storage+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0055085///transmembrane transport+++GO:0033993///response to lipid+++GO:0008203///cholesterol metabolic process+++GO:0006869///lipid transport+++GO:0043691///reverse cholesterol transport+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042632///cholesterol homeostasis+++GO:0033344///cholesterol efflux+++GO:0009720///detection of hormone stimulus+++GO:0030301///cholesterol transport+++GO:0010033///response to organic substance+++GO:0045542///positive regulation of cholesterol biosynthetic process+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0032367///intracellular cholesterol transport+++GO:0034436///glycoprotein transport+++GO:0010888///negative regulation of lipid storage+++GO:0071403///cellular response to high density lipoprotein particle stimulus+++GO:0042987///amyloid precursor protein catabolic process+++GO:0055091///phospholipid homeostasis+++GO:0010872///regulation of cholesterol esterification+++GO:0010875///positive regulation of cholesterol efflux","ATP binding cassette subfamily G member 1","[ABCG1_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family G member 1; AltName: Full=ATP-binding cassette transporter 8; AltName: Full=White protein homolog;+++[C9JKD9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family G member 1 {ECO:0000313|Ensembl:ENSP00000414541}; Flags: Fragment;+++[E9PGV9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family G member 1 {ECO:0000313|Ensembl:ENSP00000381464};"]
[9646,"'CTR9'",647,606,592,615,{"$nulls":4},"GO:0016593///Cdc73/Paf1 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0035327///transcriptionally active chromatin+++GO:0016607///nuclear speck","GO:0042169///SH2 domain binding+++GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding","GO:0016055///Wnt signaling pathway+++GO:0051571///positive regulation of histone H3-K4 methylation+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006355///regulation of transcription, DNA-templated+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0016567///protein ubiquitination+++GO:2000653///regulation of genetic imprinting+++GO:0016570///histone modification+++GO:0033523///histone H2B ubiquitination+++GO:0010390///histone monoubiquitination+++GO:0001829///trophectodermal cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2001162///positive regulation of histone H3-K79 methylation+++GO:0001832///blastocyst growth+++GO:0001835///blastocyst hatching+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0080182///histone H3-K4 trimethylation+++GO:0019827///stem cell population maintenance+++GO:0001711///endodermal cell fate commitment+++GO:0007259///JAK-STAT cascade+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0001826///inner cell mass cell differentiation","CTR9 homolog, Paf1/RNA polymerase II complex component","[CTR9_HUMAN|Reviewed]RecName: Full=RNA polymerase-associated protein CTR9 homolog; AltName: Full=SH2 domain-binding protein 1;+++[A0A2R8Y3S3_HUMAN|Unreviewed]SubName: Full=RNA polymerase-associated protein CTR9 homolog {ECO:0000313|Ensembl:ENSP00000493551}; Flags: Fragment;+++[H0YCE8_HUMAN|Unreviewed]SubName: Full=RNA polymerase-associated protein CTR9 homolog {ECO:0000313|Ensembl:ENSP00000431458}; Flags: Fragment;+++[L8E8J1_HUMAN|Unreviewed]SubName: Full=Alternative protein CTR9 {ECO:0000313|EMBL:CCQ43449.1};"]
[9656,"'MDC1'",1222,1107,975,1101.33333333333,{"$nulls":4},"GO:0005925///focal adhesion+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0070975///FHA domain binding","GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0031573///intra-S DNA damage checkpoint","mediator of DNA damage checkpoint 1","[MDC1_HUMAN|Reviewed]RecName: Full=Mediator of DNA damage checkpoint protein 1; AltName: Full=Nuclear factor with BRCT domains 1;+++[A0A087X0R2_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint protein 1 {ECO:0000313|Ensembl:ENSP00000483601};+++[A0A1U9XBC1_HUMAN|Unreviewed]SubName: Full=MDC1 {ECO:0000313|EMBL:AQY78600.1};+++[A0A291LM07_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint 1 {ECO:0000313|EMBL:ATI22100.1}; Flags: Fragment;+++[A0A291LM21_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint 1 {ECO:0000313|EMBL:ATI22101.1}; Flags: Fragment;+++[A1Z5I6_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint 1 variant 2 {ECO:0000313|EMBL:ABM47418.1}; Flags: Fragment;+++[A1Z5I7_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint 1 variant 3 {ECO:0000313|EMBL:ABM47419.1}; Flags: Fragment;+++[A1Z5I8_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint 1 variant 4 {ECO:0000313|EMBL:ABM47420.1};+++[A1Z5I9_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint 1 variant 1 {ECO:0000313|EMBL:ABM47421.1}; Flags: Fragment;+++[A2AB05_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint protein 1 {ECO:0000313|Ensembl:ENSP00000400979}; Flags: Fragment;+++[A2AB06_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint protein 1 {ECO:0000313|Ensembl:ENSP00000411310}; Flags: Fragment;+++[A2AB07_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint protein 1 {ECO:0000313|Ensembl:ENSP00000396989}; Flags: Fragment;+++[H0Y6Z8_HUMAN|Unreviewed]SubName: Full=Mediator of DNA damage checkpoint protein 1 {ECO:0000313|Ensembl:ENSP00000408962}; Flags: Fragment;+++[L8E828_HUMAN|Unreviewed]SubName: Full=Alternative protein MDC1 {ECO:0000313|EMBL:CCQ43450.1};"]
[9679,"'FAM53B'",1048,787,775,870,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus",null,"GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway","family with sequence similarity 53 member B","[FA53B_HUMAN|Reviewed]RecName: Full=Protein FAM53B {ECO:0000305}; AltName: Full=Protein simplet {ECO:0000303|PubMed:25183871};"]
[9688,"'NUP93'",637,770,731,712.666666666667,"03013///RNA transport","H01657///Nephrotic syndrome","M00427///Nuclear pore complex",null,"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005643///nuclear pore+++GO:0005635///nuclear envelope+++GO:0031965///nuclear membrane+++GO:0034399///nuclear periphery","GO:0017056///structural constituent of nuclear pore+++GO:0005515///protein binding","GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006998///nuclear envelope organization+++GO:0060395///SMAD protein signal transduction+++GO:0072015///glomerular visceral epithelial cell development+++GO:0015031///protein transport+++GO:0060391///positive regulation of SMAD protein signal transduction+++GO:0016032///viral process+++GO:0006606///protein import into nucleus+++GO:0051292///nuclear pore complex assembly+++GO:0051028///mRNA transport+++GO:0072001///renal system development+++GO:1903206///negative regulation of hydrogen peroxide-induced cell death+++GO:0090521///glomerular visceral epithelial cell migration+++GO:0006913///nucleocytoplasmic transport+++GO:0006406///mRNA export from nucleus","nucleoporin 93","[NUP93_HUMAN|Reviewed]RecName: Full=Nuclear pore complex protein Nup93; AltName: Full=93 kDa nucleoporin; AltName: Full=Nucleoporin Nup93;+++[H3BM93_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup93 {ECO:0000313|Ensembl:ENSP00000454285}; Flags: Fragment;+++[H3BMX0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup93 {ECO:0000313|Ensembl:ENSP00000454587}; Flags: Fragment;+++[H3BNG7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup93 {ECO:0000313|Ensembl:ENSP00000454844}; Flags: Fragment;+++[H3BNN5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup93 {ECO:0000313|Ensembl:ENSP00000454935}; Flags: Fragment;+++[H3BP72_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup93 {ECO:0000313|Ensembl:ENSP00000455181}; Flags: Fragment;+++[H3BP95_HUMAN|Unreviewed]RecName: Full=Nuclear pore complex protein Nup93 {ECO:0000256|RuleBase:RU364035}; Flags: Fragment;+++[H3BPA9_HUMAN|Unreviewed]RecName: Full=Nuclear pore complex protein Nup93 {ECO:0000256|RuleBase:RU364035}; Flags: Fragment;+++[H3BRD9_HUMAN|Unreviewed]RecName: Full=Nuclear pore complex protein Nup93 {ECO:0000256|RuleBase:RU364035}; Flags: Fragment;+++[H3BRI8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup93 {ECO:0000313|Ensembl:ENSP00000456264}; Flags: Fragment;+++[H3BV11_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup93 {ECO:0000313|Ensembl:ENSP00000457902}; Flags: Fragment;+++[H3BV15_HUMAN|Unreviewed]RecName: Full=Nuclear pore complex protein Nup93 {ECO:0000256|RuleBase:RU364035}; Flags: Fragment;+++[H3BVE2_HUMAN|Unreviewed]RecName: Full=Nuclear pore complex protein Nup93 {ECO:0000256|RuleBase:RU364035}; Flags: Fragment;+++[H3BVG0_HUMAN|Unreviewed]RecName: Full=Nuclear pore complex protein Nup93 {ECO:0000256|RuleBase:RU364035};"]
[9711,"'RUBCN'",721,768.97,747,745.656666666667,"04140///Autophagy - animal","H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0005770///late endosome+++GO:0005769///early endosome","GO:0005515///protein binding","GO:0071985///multivesicular body sorting pathway+++GO:0006897///endocytosis+++GO:1901097///negative regulation of autophagosome maturation+++GO:0002376///immune system process+++GO:0006914///autophagy+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0045806///negative regulation of endocytosis+++GO:0010507///negative regulation of autophagy+++GO:0006909///phagocytosis","RUN and cysteine rich domain containing beclin 1 interacting protein","[RUBIC_HUMAN|Reviewed]RecName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000312|HGNC:HGNC:28991}; Short=Rubicon; AltName: Full=Beclin-1 associated RUN domain containing protein; Short=Baron;+++[A0A096LNI3_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000485041}; Flags: Fragment;+++[E9PEM3_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000390962};+++[H0Y6E6_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000405115}; Flags: Fragment;+++[H7C357_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000409618}; Flags: Fragment;+++[H7C3H3_HUMAN|Unreviewed]SubName: Full=Run domain Beclin-1-interacting and cysteine-rich domain-containing protein {ECO:0000313|Ensembl:ENSP00000411894}; Flags: Fragment;+++[Q8N4U6_HUMAN|Unreviewed]SubName: Full=KIAA0226 protein {ECO:0000313|EMBL:AAH33615.1};"]
[9712,"'USP6NL'",467,519,393.97,459.99,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0032588///trans-Golgi network membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0048227///plasma membrane to endosome transport+++GO:0043547///positive regulation of GTPase activity+++GO:0035526///retrograde transport, plasma membrane to Golgi+++GO:0090630///activation of GTPase activity+++GO:1903358///regulation of Golgi organization+++GO:1902017///regulation of cilium assembly+++GO:0006886///intracellular protein transport+++GO:0007030///Golgi organization","USP6 N-terminal like","[US6NL_HUMAN|Reviewed]RecName: Full=USP6 N-terminal-like protein; AltName: Full=Related to the N-terminus of tre; Short=RN-tre;+++[Q96FW8_HUMAN|Unreviewed]SubName: Full=USP6NL protein {ECO:0000313|EMBL:AAH10351.1}; Flags: Fragment;+++[V9GYH2_HUMAN|Unreviewed]SubName: Full=USP6 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000476748};+++[X6RAB3_HUMAN|Unreviewed]SubName: Full=USP6 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000368539};"]
[9729,"'KIAA0408'",6.52,9.97,0,5.49666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"KIAA0408","[K0408_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0408;+++[E9PQS0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000434384}; Flags: Fragment;+++[H0YEM8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000436178}; Flags: Fragment;"]
[973,"'CD79A'",87,143,123,117.666666666667,"04662///B cell receptor signaling pathway+++05340///Primary immunodeficiency","H00085///Agammaglobulinemias",null,null,"GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0019815///B cell receptor complex+++GO:0009897///external side of plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0051289///protein homotetramerization+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0050853///B cell receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0007166///cell surface receptor signaling pathway+++GO:0042100///B cell proliferation+++GO:0042113///B cell activation","CD79a molecule","[CD79A_HUMAN|Reviewed]RecName: Full=B-cell antigen receptor complex-associated protein alpha chain; AltName: Full=Ig-alpha; AltName: Full=MB-1 membrane glycoprotein; AltName: Full=Membrane-bound immunoglobulin-associated protein; AltName: Full=Surface IgM-associated protein; AltName: CD_antigen=CD79a; Flags: Precursor;+++[M0QX61_HUMAN|Unreviewed]SubName: Full=B-cell antigen receptor complex-associated protein alpha chain {ECO:0000313|Ensembl:ENSP00000468922}; Flags: Fragment;"]
[9730,"'DCAF1'",500,445,406,450.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome+++GO:0001650///fibrillar center+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex","GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990244///histone kinase activity (H2A-T120 specific)+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0030331///estrogen receptor binding","GO:0030183///B cell differentiation+++GO:0016032///viral process+++GO:0033151///V(D)J recombination+++GO:0016310///phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1990245///histone H2A-T120 phosphorylation+++GO:0006325///chromatin organization+++GO:0016567///protein ubiquitination+++GO:0035212///cell competition in a multicellular organism","DDB1 and CUL4 associated factor 1","[DCAF1_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911}; AltName: Full=HIV-1 Vpr-binding protein; Short=VprBP; AltName: Full=Serine/threonine-protein kinase VPRBP; EC=2.7.11.1; AltName: Full=Vpr-interacting protein;"]
[9731,"'CEP104'",719.66,729,535.68,661.446666666667,null,"H00530///Joubert syndrome",null,null,"GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0005814///centriole+++GO:0000922///spindle pole","GO:0016594///glycine binding+++GO:0016595///glutamate binding+++GO:0016596///thienylcyclohexylpiperidine binding+++GO:0005515///protein binding",null,"centrosomal protein 104","[CE104_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 104 kDa; Short=Cep104;+++[H7C0J5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000395283}; Flags: Fragment;+++[J3QLL3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000463605}; Flags: Fragment;+++[Q5SR26_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000411927}; Flags: Fragment;+++[Q5SR27_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000394989}; Flags: Fragment;"]
[9732,"'DOCK4'",118,87,60,88.3333333333333,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0005096///GTPase activator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0048365///Rac GTPase binding+++GO:0017124///SH3 domain binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030165///PDZ domain binding+++GO:0005515///protein binding","GO:1904694///negative regulation of vascular smooth muscle contraction+++GO:0007264///small GTPase mediated signal transduction+++GO:0060326///cell chemotaxis+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0043547///positive regulation of GTPase activity","dedicator of cytokinesis 4","[DOCK4_HUMAN|Reviewed]RecName: Full=Dedicator of cytokinesis protein 4;+++[A0A024R749_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4, isoform CRA_a {ECO:0000313|EMBL:EAW83455.1};+++[A0A2X0SFR8_HUMAN|Unreviewed]SubName: Full=DOCK4 {ECO:0000313|EMBL:SPT35744.1}; Flags: Fragment;+++[A4D0S8_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:EAL24377.1};+++[C9J637_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406468}; Flags: Fragment;+++[C9J7D9_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406298}; Flags: Fragment;+++[C9JDB3_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000403504}; Flags: Fragment;+++[F5GXW1_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000440944};+++[F8WES4_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000393486};+++[H0Y599_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000397412}; Flags: Fragment;+++[H0Y7H7_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000412834}; Flags: Fragment;+++[Q149N2_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17695.1};+++[Q149N5_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17690.1};+++[Q149N6_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:AAI17689.1};+++[Q75MU6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DOCK4 {ECO:0000313|EMBL:AAS07431.1}; Flags: Fragment;"]
[9733,"'SART3'",670,658,570,632.666666666667,null,"H00791///Disseminated superficial actinic porokeratosis (DSAP)",null,null,"GO:0071002///U4atac/U6atac snRNP+++GO:0061574///ASAP complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005691///U6atac snRNP+++GO:0015030///Cajal body+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0071001///U4/U6 snRNP","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0030624///U6atac snRNA binding+++GO:0003676///nucleic acid binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0030621///U4 snRNA binding+++GO:0017070///U6 snRNA binding","GO:0010468///regulation of gene expression+++GO:0000902///cell morphogenesis+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0048872///homeostasis of number of cells+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006334///nucleosome assembly+++GO:0000387///spliceosomal snRNP assembly+++GO:1903586///positive regulation of histone deubiquitination+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing","spliceosome associated factor 3, U4/U6 recycling protein","[SART3_HUMAN|Reviewed]RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000305}; Short=SART-3 {ECO:0000312|EMBL:BAA78384.1}; AltName: Full=Tat-interacting protein of 110 kDa {ECO:0000303|PubMed:11959860}; Short=Tip110 {ECO:0000303|PubMed:11959860}; AltName: Full=p110 nuclear RNA-binding protein {ECO:0000303|PubMed:12032085};+++[F8VV04_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449386}; Flags: Fragment;+++[F8VVK9_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449602}; Flags: Fragment;+++[F8VZM2_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447324}; Flags: Fragment;+++[F8W667_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000446577};+++[H0YHU8_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447875}; Flags: Fragment;"]
[9734,"'HDAC9'",1253,1303,873,1143,"05034///Alcoholism+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0000118///histone deacetylase complex+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0035097///histone methyltransferase complex","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0071889///14-3-3 protein binding+++GO:0070491///repressing transcription factor binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0008134///transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0033558///protein deacetylase activity+++GO:0003682///chromatin binding+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding+++GO:0033613///activating transcription factor binding+++GO:0005080///protein kinase C binding+++GO:0003714///transcription corepressor activity+++GO:0016787///hydrolase activity","GO:0006954///inflammatory response+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0006325///chromatin organization+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0032703///negative regulation of interleukin-2 production+++GO:0042113///B cell activation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0007507///heart development+++GO:0032869///cellular response to insulin stimulus+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0030182///neuron differentiation+++GO:0007043///cell-cell junction assembly+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0001570///vasculogenesis+++GO:0030183///B cell differentiation+++GO:0001975///response to amphetamine+++GO:0034983///peptidyl-lysine deacetylation","histone deacetylase 9","[HDAC9_HUMAN|Reviewed]RecName: Full=Histone deacetylase 9; Short=HD9; EC=3.5.1.98; AltName: Full=Histone deacetylase 7B; Short=HD7; Short=HD7b; AltName: Full=Histone deacetylase-related protein; AltName: Full=MEF2-interacting transcription repressor MITR;+++[B5MCF1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000384017};+++[B7Z3P7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79008, highly similar to Histone deacetylase 9 {ECO:0000313|EMBL:BAH14480.1};+++[C9IZS0_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000412497}; Flags: Fragment;+++[C9J1W4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000392564}; Flags: Fragment;+++[C9J835_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000411422}; Flags: Fragment;+++[C9JD56_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000404763}; Flags: Fragment;+++[C9JLX1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000409003}; Flags: Fragment;+++[F8WDS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000415095};+++[Q75N08_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07409.1}; Flags: Fragment;+++[Q75N09_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07402.1}; Flags: Fragment;+++[Q75N10_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07401.1}; Flags: Fragment;+++[Q75N14_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07423.1}; Flags: Fragment;+++[Q75N15_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07424.1}; Flags: Fragment;+++[Q75N16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07422.1}; Flags: Fragment;+++[Q9Y6V1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAD15364.2};"]
[9735,"'KNTC1'",60,86,46,64,{"$nulls":4},"GO:0005829///cytosol+++GO:0005828///kinetochore microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:1990423///RZZ complex+++GO:0005856///cytoskeleton+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007096///regulation of exit from mitosis+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0051301///cell division","kinetochore associated 1","[KNTC1_HUMAN|Reviewed]RecName: Full=Kinetochore-associated protein 1; AltName: Full=Rough deal homolog; Short=HsROD; Short=Rod; Short=hRod;+++[E7ES84_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397992};+++[F5H5V0_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408760};+++[H0YFL5_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439119}; Flags: Fragment;+++[J3KQF2_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397140}; Flags: Fragment;"]
[9736,"'USP34'",2366,2152,1539,2019,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0004197///cysteine-type endopeptidase activity","GO:0071108///protein K48-linked deubiquitination+++GO:0006508///proteolysis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031647///regulation of protein stability+++GO:0016579///protein deubiquitination","ubiquitin specific peptidase 34","[UBP34_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 34; EC=3.4.19.12 {ECO:0000269|PubMed:14715245, ECO:0000269|PubMed:21383061}; AltName: Full=Deubiquitinating enzyme 34; AltName: Full=Ubiquitin thioesterase 34; AltName: Full=Ubiquitin-specific-processing protease 34;+++[A0A0C4DG73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000410559}; Flags: Fragment;+++[H7BZ73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000388129}; Flags: Fragment;+++[H7C150_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398489}; Flags: Fragment;+++[H7C183_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398960}; Flags: Fragment;"]
[9737,"'GPRASP1'",149,95,111,118.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0008333///endosome to lysosome transport+++GO:1990172///G protein-coupled receptor catabolic process","G protein-coupled receptor associated sorting protein 1","[GASP1_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 1; Short=GASP-1;"]
[9738,"'CCP110'",145,167,113,141.666666666667,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0030030///cell projection organization+++GO:0032465///regulation of cytokinesis+++GO:0007099///centriole replication+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0045724///positive regulation of cilium assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1902018///negative regulation of cilium assembly+++GO:0016579///protein deubiquitination+++GO:0051298///centrosome duplication+++GO:0032053///ciliary basal body organization","centriolar coiled-coil protein 110","[CP110_HUMAN|Reviewed]RecName: Full=Centriolar coiled-coil protein of 110 kDa; AltName: Full=Centrosomal protein of 110 kDa; Short=CP110; Short=Cep110;+++[A0A024QYV8_HUMAN|Unreviewed]SubName: Full=CP110 protein, isoform CRA_a {ECO:0000313|EMBL:EAW50288.1};+++[H3BMS1_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000454514}; Flags: Fragment;+++[H3BVH3_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000458123};+++[I3L262_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000459410}; Flags: Fragment;"]
[9739,"'SETD1A'",1170,1195,1177,1180.66666666667,"00310///Lysine degradation",null,null,"R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine","GO:0048188///Set1C/COMPASS complex+++GO:0016607///nuclear speck+++GO:0000790///nuclear chromatin+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0016740///transferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008013///beta-catenin binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008134///transcription factor binding","GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0032259///methylation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:1902275///regulation of chromatin organization+++GO:0051568///histone H3-K4 methylation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization","SET domain containing 1A","[SET1A_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETD1A; EC=2.1.1.43; AltName: Full=Lysine N-methyltransferase 2F; AltName: Full=SET domain-containing protein 1A; Short=hSET1A; AltName: Full=Set1/Ash2 histone methyltransferase complex subunit SET1;+++[C9J2Z9_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETD1A {ECO:0000313|Ensembl:ENSP00000391408}; Flags: Fragment;+++[L0R6N9_HUMAN|Unreviewed]SubName: Full=Alternative protein SETD1A {ECO:0000313|EMBL:CCO13810.1};"]
[974,"'CD79B'",7,4,5,5.33333333333333,"04662///B cell receptor signaling pathway","H00085///Agammaglobulinemias",null,null,"GO:0009897///external side of plasma membrane+++GO:0019815///B cell receptor complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0004888///transmembrane signaling receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0002376///immune system process+++GO:0051260///protein homooligomerization+++GO:0050853///B cell receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0002250///adaptive immune response","CD79b molecule","[CD79B_HUMAN|Reviewed]RecName: Full=B-cell antigen receptor complex-associated protein beta chain; AltName: Full=B-cell-specific glycoprotein B29; AltName: Full=Ig-beta; AltName: Full=Immunoglobulin-associated B29 protein; AltName: CD_antigen=CD79b; Flags: Precursor;+++[A0A192GQF2_HUMAN|Unreviewed]SubName: Full=B-cell antigen receptor complex-associated protein beta chain isoform 3 {ECO:0000313|EMBL:ANK58153.1}; Flags: Fragment;+++[Q6PIS4_HUMAN|Unreviewed]SubName: Full=CD79B protein {ECO:0000313|EMBL:AAH30210.1};"]
[9741,"'LAPTM4A'",4441,4304,4479,4408,"04142///Lysosome",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding",null,"lysosomal protein transmembrane 4 alpha","[LAP4A_HUMAN|Reviewed]RecName: Full=Lysosomal-associated transmembrane protein 4A; AltName: Full=Golgi 4-transmembrane-spanning transporter MTP;+++[Q4ZG00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAX88938.1}; Flags: Fragment;+++[Q53QZ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAY24172.1}; Flags: Fragment;+++[Q6IBP4_HUMAN|Unreviewed]SubName: Full=LAPTM4A protein {ECO:0000313|EMBL:CAG33039.1}; SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH93075.1}; SubName: Full=Lysosomal-associated protein transmembrane 4 alpha, isoform CRA_b {ECO:0000313|EMBL:EAX00834.1};+++[Q9BTU8_HUMAN|Unreviewed]SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH03158.1};"]
[9742,"'IFT140'",631,600,620,617,null,"H02157///Short-rib thoracic dysplasia",null,null,"GO:0005737///cytoplasm+++GO:0097730///non-motile cilium+++GO:0005929///cilium+++GO:0097542///ciliary tip+++GO:0036064///ciliary basal body+++GO:0030991///intraciliary transport particle A+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0032391///photoreceptor connecting cilium+++GO:0005930///axoneme+++GO:0001750///photoreceptor outer segment+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0003674///molecular_function","GO:0035721///intraciliary retrograde transport+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1990403///embryonic brain development+++GO:0035108///limb morphogenesis+++GO:0008589///regulation of smoothened signaling pathway+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0021532///neural tube patterning+++GO:0007368///determination of left/right symmetry+++GO:1905515///non-motile cilium assembly+++GO:0048705///skeletal system morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0035845///photoreceptor cell outer segment organization+++GO:1902017///regulation of cilium assembly+++GO:0030030///cell projection organization+++GO:0042733///embryonic digit morphogenesis+++GO:0060041///retina development in camera-type eye+++GO:0007507///heart development+++GO:0031076///embryonic camera-type eye development+++GO:0072001///renal system development","intraflagellar transport 140","[IF140_HUMAN|Reviewed]RecName: Full=Intraflagellar transport protein 140 homolog; AltName: Full=WD and tetratricopeptide repeats protein 2;+++[H3BNC5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000454781}; Flags: Fragment;+++[H3BTA5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000457092}; Flags: Fragment;+++[I3L0Y8_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000458439}; Flags: Fragment;+++[J3KPW0_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000380562};+++[Q96RY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein gs114 {ECO:0000313|EMBL:AAK61287.1};"]
[9743,"'ARHGAP32'",386,425,288,366.333333333333,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0015629///actin cytoskeleton+++GO:0005783///endoplasmic reticulum+++GO:0014069///postsynaptic density+++GO:0005789///endoplasmic reticulum membrane+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0001650///fibrillar center","GO:0035091///phosphatidylinositol binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 32","[RHG32_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 32; AltName: Full=Brain-specific Rho GTPase-activating protein; AltName: Full=GAB-associated Cdc42/Rac GTPase-activating protein; AltName: Full=GC-GAP; AltName: Full=GTPase regulator interacting with TrkA; AltName: Full=Rho-type GTPase-activating protein 32; AltName: Full=Rho/Cdc42/Rac GTPase-activating protein RICS; AltName: Full=RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; AltName: Full=p200RhoGAP; AltName: Full=p250GAP;+++[A0A024R3K8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_c {ECO:0000313|EMBL:EAW67737.1};+++[A0A024R3N1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_a {ECO:0000313|EMBL:EAW67733.1};+++[A0A2X0SFD0_HUMAN|Unreviewed]SubName: Full=ARHGAP32 {ECO:0000313|EMBL:SPT35703.1}; Flags: Fragment;+++[E9PRH3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432303}; Flags: Fragment;+++[G3V174_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432468}; SubName: Full=Rho GTPase-activating protein, isoform CRA_b {ECO:0000313|EMBL:EAW67734.1};+++[Q86T64_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451F1115 {ECO:0000313|EMBL:CAD89974.1}; Flags: Fragment;+++[Q86UT2_HUMAN|Unreviewed]SubName: Full=RICS protein {ECO:0000313|EMBL:AAH51236.1}; Flags: Fragment;"]
[9744,"'ACAP1'",35.12,25.21,39.09,33.14,"04144///Endocytosis",{"$nulls":3},"GO:0055038///recycling endosome membrane+++GO:0005768///endosome+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity+++GO:0015031///protein transport","ArfGAP with coiled-coil, ankyrin repeat and PH domains 1","[ACAP1_HUMAN|Reviewed]RecName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; AltName: Full=Centaurin-beta-1; Short=Cnt-b1;+++[I3L0K9_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000458173}; Flags: Fragment;+++[I3L268_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459422}; Flags: Fragment;"]
[9745,"'ZNF536'",521,359,285,388.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0045665///negative regulation of neuron differentiation+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger protein 536","[ZN536_HUMAN|Reviewed]RecName: Full=Zinc finger protein 536;+++[A7E228_HUMAN|Unreviewed]SubName: Full=ZNF536 protein {ECO:0000313|EMBL:AAI50172.1};+++[K7EJP8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465268}; Flags: Fragment;+++[K7EKT4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465771}; Flags: Fragment;+++[K7EQN6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000467909}; Flags: Fragment;"]
[9746,"'CLSTN3'",3419,4381,4571,4123.66666666667,{"$nulls":4},"GO:0099061///integral component of postsynaptic density membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0098982///GABA-ergic synapse+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0098978///glutamatergic synapse+++GO:0014069///postsynaptic density","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051965///positive regulation of synapse assembly+++GO:0051932///synaptic transmission, GABAergic+++GO:1905606///regulation of presynapse assembly+++GO:0001558///regulation of cell growth+++GO:0050806///positive regulation of synaptic transmission+++GO:1902474///positive regulation of protein localization to synapse+++GO:0007155///cell adhesion+++GO:0007416///synapse assembly+++GO:0035249///synaptic transmission, glutamatergic","calsyntenin 3","[CSTN3_HUMAN|Reviewed]RecName: Full=Calsyntenin-3; AltName: Full=Alcadein-beta; Short=Alc-beta; Flags: Precursor;+++[F5H172_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443959}; Flags: Fragment;+++[F5H5C6_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443490}; Flags: Fragment;+++[F5H5D7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443468}; Flags: Fragment;+++[F5H746_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442801}; Flags: Fragment;+++[F5H7C7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442612}; Flags: Fragment;+++[Q8IUW6_HUMAN|Unreviewed]SubName: Full=CLSTN3 protein {ECO:0000313|EMBL:AAH39075.1};"]
[9747,"'TCAF1'",2480,3075,2089,2548,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0044325///ion channel binding","GO:1901529///positive regulation of anion channel activity+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0030336///negative regulation of cell migration","TRPM8 channel associated factor 1","[TCAF1_HUMAN|Reviewed]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[B4DST7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58406, weakly similar to Mus musculus experimental autoimmune prostatitis antigen 2 (Eapa2), mRNA {ECO:0000313|EMBL:BAG61749.1};+++[C9J648_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000418432}; Flags: Fragment;+++[C9J9F4_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000417600}; Flags: Fragment;+++[C9JD13_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000420607}; Flags: Fragment;+++[C9K0E7_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000419622}; Flags: Fragment;"]
[9748,"'SLK'",2052,1517,1124,1564.33333333333,"04114///Oocyte meiosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0031252///cell leading edge","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0042802///identical protein binding","GO:0030334///regulation of cell migration+++GO:0023014///signal transduction by protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031122///cytoplasmic microtubule organization+++GO:0006915///apoptotic process+++GO:0051893///regulation of focal adhesion assembly+++GO:0007346///regulation of mitotic cell cycle+++GO:0032147///activation of protein kinase activity","STE20 like kinase","[SLK_HUMAN|Reviewed]RecName: Full=STE20-like serine/threonine-protein kinase; Short=STE20-like kinase; Short=hSLK; EC=2.7.11.1; AltName: Full=CTCL tumor antigen se20-9; AltName: Full=STE20-related serine/threonine-protein kinase; Short=STE20-related kinase; AltName: Full=Serine/threonine-protein kinase 2;+++[L8ECF1_HUMAN|Unreviewed]SubName: Full=Alternative protein SLK {ECO:0000313|EMBL:CCQ43457.1};"]
[9749,"'PHACTR2'",1297,1398,868.97,1187.99,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031092///platelet alpha granule membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0004864///protein phosphatase inhibitor activity","GO:0002576///platelet degranulation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","phosphatase and actin regulator 2","[PHAR2_HUMAN|Reviewed]RecName: Full=Phosphatase and actin regulator 2;+++[F5H858_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[F6TH74_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[H9KVA6_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};+++[J3KP75_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};"]
[975,"'CD81'",9761,11577,12676,11338,"05144///Malaria+++04662///B cell receptor signaling pathway+++05160///Hepatitis C","H00088///Common variable immunodeficiency (CVID)",null,null,"GO:0001772///immunological synapse+++GO:0031982///vesicle+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005925///focal adhesion","GO:0001618///virus receptor activity+++GO:0023026///MHC class II protein complex binding+++GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:1990459///transferrin receptor binding","GO:0008284///positive regulation of cell proliferation+++GO:0046718///viral entry into host cell+++GO:0061462///protein localization to lysosome+++GO:0031647///regulation of protein stability+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000145///regulation of cell motility+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:0008104///protein localization+++GO:0050776///regulation of immune response+++GO:0030449///regulation of complement activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000187///activation of MAPK activity+++GO:0031623///receptor internalization+++GO:0008283///cell proliferation+++GO:0016032///viral process+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0043128///positive regulation of 1-phosphatidylinositol 4-kinase activity+++GO:0030890///positive regulation of B cell proliferation+++GO:1904352///positive regulation of protein catabolic process in the vacuole+++GO:0007166///cell surface receptor signaling pathway","CD81 molecule","[CD81_HUMAN|Reviewed]RecName: Full=CD81 antigen; AltName: Full=26 kDa cell surface protein TAPA-1; AltName: Full=Target of the antiproliferative antibody 1; AltName: Full=Tetraspanin-28; Short=Tspan-28; AltName: CD_antigen=CD81;+++[A0A024RCB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[A6NMH8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PIF1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJK1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PM31_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000433178}; Flags: Fragment;+++[E9PPF5_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432723}; Flags: Fragment;+++[E9PQV4_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432497}; Flags: Fragment;+++[E9PRJ8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDJ9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDL9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YEE2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[9750,"'RIPOR2'",2,5,2,3,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0060171///stereocilium membrane+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0032420///stereocilium","GO:0071889///14-3-3 protein binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0071158///positive regulation of cell cycle arrest+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0007605///sensory perception of sound+++GO:1903904///negative regulation of establishment of T cell polarity+++GO:0071260///cellular response to mechanical stimulus+++GO:2000405///negative regulation of T cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0051491///positive regulation of filopodium assembly+++GO:0045663///positive regulation of myoblast differentiation+++GO:0006935///chemotaxis+++GO:1905872///negative regulation of protein localization to cell leading edge+++GO:0042130///negative regulation of T cell proliferation+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:2001107///negative regulation of Rho guanyl-nucleotide exchange factor activity+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0009968///negative regulation of signal transduction+++GO:0048741///skeletal muscle fiber development+++GO:1901741///positive regulation of myoblast fusion+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0030154///cell differentiation+++GO:0045184///establishment of protein localization+++GO:2000114///regulation of establishment of cell polarity+++GO:1990869///cellular response to chemokine+++GO:0051260///protein homooligomerization+++GO:1901673///regulation of mitotic spindle assembly+++GO:0090023///positive regulation of neutrophil chemotaxis","RHO family interacting cell polarization regulator 2","[RIPR2_HUMAN|Reviewed]RecName: Full=Rho family-interacting cell polarization regulator 2;+++[A0A024QZY9_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_c {ECO:0000313|EMBL:EAW55471.1};+++[A0A024R028_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_a {ECO:0000313|EMBL:EAW55469.1};+++[A0A2R8Y4B9_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493881}; Flags: Fragment;+++[A0A2R8Y4N2_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493948}; Flags: Fragment;+++[A0A2R8Y7B3_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000495879};+++[A0A2R8YEE0_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494268};+++[A0A2R8YF77_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494904};+++[B7Z5J9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56137 {ECO:0000313|EMBL:BAH12935.1};+++[B7Z6D6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60883 {ECO:0000313|EMBL:BAH13222.1};+++[B7Z6U4_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441305}; SubName: Full=cDNA FLJ56038 {ECO:0000313|EMBL:BAH13380.1};+++[F5GX51_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441138};+++[F5H029_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000438425};"]
[9751,"'SNPH'",243,282,259,261.333333333333,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0005881///cytoplasmic microtubule+++GO:0042734///presynaptic membrane+++GO:0016021///integral component of membrane","GO:0017075///syntaxin-1 binding","GO:0016081///synaptic vesicle docking+++GO:0007269///neurotransmitter secretion+++GO:0030182///neuron differentiation+++GO:0007420///brain development","syntaphilin","[SNPH_HUMAN|Reviewed]RecName: Full=Syntaphilin;"]
[9752,"'PCDHA9'",2.14,20.08,13.69,11.97,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","protocadherin alpha 9","[PCDA9_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-9; Short=PCDH-alpha-9; Flags: Precursor;"]
[9753,"'ZSCAN12'",128,150.99,110.97,129.986666666667,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and SCAN domain containing 12","[ZSC12_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 12; AltName: Full=Zinc finger protein 305; AltName: Full=Zinc finger protein 96;+++[A0A024RCI2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 96, isoform CRA_a {ECO:0000313|EMBL:EAX03162.1};"]
[9754,"'STARD8'",49,27,30,35.3333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0008289///lipid binding","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity","StAR related lipid transfer domain containing 8","[STAR8_HUMAN|Reviewed]RecName: Full=StAR-related lipid transfer protein 8; AltName: Full=Deleted in liver cancer 3 protein; Short=DLC-3; AltName: Full=START domain-containing protein 8; Short=StARD8; AltName: Full=START-GAP3;+++[A0A2X0U2P1_HUMAN|Unreviewed]SubName: Full=STARD8 {ECO:0000313|EMBL:SPT35801.1}; Flags: Fragment;+++[E5RFN7_HUMAN|Unreviewed]SubName: Full=StAR-related lipid transfer protein 8 {ECO:0000313|Ensembl:ENSP00000428031};"]
[9755,"'TBKBP1'",630,548,654,610.666666666667,"04622///RIG-I-like receptor signaling pathway",{"$nulls":4},"GO:0005515///protein binding","GO:0002376///immune system process+++GO:0016032///viral process+++GO:0045087///innate immune response","TBK1 binding protein 1","[TBKB1_HUMAN|Reviewed]RecName: Full=TANK-binding kinase 1-binding protein 1; Short=TBK1-binding protein 1;+++[D3DTT5_HUMAN|Unreviewed]SubName: Full=TBK1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94806.1};+++[F5H1U4_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000446365}; Flags: Fragment;+++[J3KS71_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000462339}; Flags: Fragment;"]
[9757,"'KMT2B'",1078,1171,937,1062,"00310///Lysine degradation","H01613///Follicular lymphoma+++H00831///Primary dystonia",null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008168///methyltransferase activity","GO:0051568///histone H3-K4 methylation+++GO:0032259///methylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0009994///oocyte differentiation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization+++GO:0016458///gene silencing+++GO:0007613///memory+++GO:0080182///histone H3-K4 trimethylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0030728///ovulation","lysine methyltransferase 2B","[KMT2B_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase 2B; Short=Lysine N-methyltransferase 2B; EC=2.1.1.43; AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 4; AltName: Full=Trithorax homolog 2; AltName: Full=WW domain-binding protein 7; Short=WBP-7;"]
[9758,"'FRMPD4'",2,0,0,0.666666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine","GO:0008289///lipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005515///protein binding","GO:0051835///positive regulation of synapse structural plasticity+++GO:0098974///postsynaptic actin cytoskeleton organization","FERM and PDZ domain containing 4","[FRPD4_HUMAN|Reviewed]RecName: Full=FERM and PDZ domain-containing protein 4; AltName: Full=PDZ domain-containing protein 10; AltName: Full=PSD-95-interacting regulator of spine morphogenesis; Short=Preso;+++[A0A087WYX8_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000482182};+++[A0A1W2PQW0_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000492353}; Flags: Fragment;+++[B7ZLE1_HUMAN|Unreviewed]SubName: Full=FRMPD4 protein {ECO:0000313|EMBL:AAI43747.1};"]
[9759,"'HDAC4'",160,183,117,153.333333333333,"05203///Viral carcinogenesis+++05034///Alcoholism+++05169///Epstein-Barr virus infection+++05165///Human papillomavirus infection+++04371///Apelin signaling pathway","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0017053///transcriptional repressor complex+++GO:0005654///nucleoplasm+++GO:0042641///actomyosin+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0031672///A band+++GO:0030018///Z disc+++GO:0031594///neuromuscular junction+++GO:0030017///sarcomere+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:1990841///promoter-specific chromatin binding+++GO:0004407///histone deacetylase activity+++GO:0042826///histone deacetylase binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033613///activating transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0008270///zinc ion binding+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0030955///potassium ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003714///transcription corepressor activity+++GO:0070491///repressing transcription factor binding+++GO:0033558///protein deacetylase activity+++GO:0005515///protein binding+++GO:0001085///RNA polymerase II transcription factor binding","GO:0006954///inflammatory response+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0040029///regulation of gene expression, epigenetic+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0033235///positive regulation of protein sumoylation+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0030183///B cell differentiation+++GO:0006338///chromatin remodeling+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070555///response to interleukin-1+++GO:0008284///positive regulation of cell proliferation+++GO:0001501///skeletal system development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0002076///osteoblast development+++GO:0006476///protein deacetylation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0042113///B cell activation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0007399///nervous system development+++GO:0045820///negative regulation of glycolytic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0043393///regulation of protein binding+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0016575///histone deacetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0006325///chromatin organization+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010832///negative regulation of myotube differentiation","histone deacetylase 4","[HDAC4_HUMAN|Reviewed]RecName: Full=Histone deacetylase 4; Short=HD4; EC=3.5.1.98;+++[C9J0X4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000392912}; Flags: Fragment;+++[C9J481_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000405226}; Flags: Fragment;+++[F5H0B1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000438111}; Flags: Fragment;+++[H7BZT3_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000391226}; Flags: Fragment;+++[H7C397_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000410551}; Flags: Fragment;"]
[976,"'ADGRE5'",91,82,89,87.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0030667///secretory granule membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007267///cell-cell signaling+++GO:0007155///cell adhesion+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0043312///neutrophil degranulation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","adhesion G protein-coupled receptor E5","[CD97_HUMAN|Reviewed]RecName: Full=CD97 antigen; AltName: Full=Leukocyte antigen CD97; AltName: CD_antigen=CD97; Contains: RecName: Full=CD97 antigen subunit alpha; Contains: RecName: Full=CD97 antigen subunit beta; Flags: Precursor;+++[K7EKV5_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000465800}; Flags: Fragment;+++[K7EPE8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467351}; Flags: Fragment;+++[K7EPP8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467478}; Flags: Fragment;"]
[9760,"'TOX'",664,935,782,793.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0048535///lymph node development+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030098///lymphocyte differentiation+++GO:0048541///Peyer's patch development","thymocyte selection associated high mobility group box","[TOX_HUMAN|Reviewed]RecName: Full=Thymocyte selection-associated high mobility group box protein TOX; AltName: Full=Thymus high mobility group box protein TOX;"]
[9761,"'MLEC'",4368,4151,3989,4169.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0035579///specific granule membrane+++GO:0005886///plasma membrane","GO:0019899///enzyme binding+++GO:0030246///carbohydrate binding","GO:0005975///carbohydrate metabolic process+++GO:0043312///neutrophil degranulation+++GO:0006457///protein folding","malectin","[MLEC_HUMAN|Reviewed]RecName: Full=Malectin; Flags: Precursor;+++[F5GX14_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000440746};+++[F5H1S8_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000438950}; Flags: Fragment;+++[H0YG07_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000441247}; Flags: Fragment;"]
[9762,"'LZTS3'",285,312,313,303.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density",null,"GO:0061001///regulation of dendritic spine morphogenesis","leucine zipper tumor suppressor family member 3","[LZTS3_HUMAN|Reviewed]RecName: Full=Leucine zipper putative tumor suppressor 3 {ECO:0000305}; AltName: Full=ProSAP-interacting protein 1 {ECO:0000250|UniProtKB:Q8K1Q4}; Short=ProSAPiP1 {ECO:0000250|UniProtKB:Q8K1Q4};"]
[9764,"'KIAA0513'",394,409,289.01,364.003333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm",null,null,"KIAA0513","[K0513_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0513;+++[H3BMU3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454547}; Flags: Fragment;+++[H3BNA7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454758}; Flags: Fragment;"]
[9765,"'ZFYVE16'",307,198,166,223.666666666667,"04350///TGF-beta signaling pathway+++04144///Endocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm","GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0046872///metal ion binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding","GO:0016050///vesicle organization+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0030509///BMP signaling pathway+++GO:0016197///endosomal transport+++GO:0006622///protein targeting to lysosome","zinc finger FYVE-type containing 16","[ZFY16_HUMAN|Reviewed]RecName: Full=Zinc finger FYVE domain-containing protein 16; AltName: Full=Endofin; AltName: Full=Endosome-associated FYVE domain protein;+++[A0A024RAL3_HUMAN|Unreviewed]RecName: Full=Zinc finger FYVE domain-containing protein {ECO:0000256|PIRNR:PIRNR037289};+++[D6RC80_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000422356}; Flags: Fragment;+++[H0Y8R0_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000421785}; Flags: Fragment;+++[H0YAA4_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426500}; Flags: Fragment;+++[H0YAB1_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426536}; Flags: Fragment;"]
[9766,"'SUSD6'",520,604,502,542,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0008219///cell death","sushi domain containing 6","[SUSD6_HUMAN|Reviewed]RecName: Full=Sushi domain-containing protein 6 {ECO:0000312|HGNC:HGNC:19956}; AltName: Full=Drug-activated gene overexpressed protein {ECO:0000303|PubMed:24652652}; Flags: Precursor;"]
[9767,"'JADE3'",84,82,67,77.6666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000123///histone acetyltransferase complex","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0043981///histone H4-K5 acetylation+++GO:0043966///histone H3 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0043982///histone H4-K8 acetylation","jade family PHD finger 3","[JADE3_HUMAN|Reviewed]RecName: Full=Protein Jade-3; AltName: Full=Jade family PHD finger protein 3; AltName: Full=PHD finger protein 16;+++[A0A024R1A2_HUMAN|Unreviewed]SubName: Full=PHD finger protein 16, isoform CRA_a {ECO:0000313|EMBL:EAW59278.1};+++[F2Z2B6_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000400584}; Flags: Fragment;+++[F2Z3N8_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000391009}; Flags: Fragment;"]
[9768,"'PCLAF'",1.05,2,1,1.35,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0003682///chromatin binding","GO:0006260///DNA replication+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0007098///centrosome cycle+++GO:0006281///DNA repair+++GO:0019985///translesion synthesis","PCNA clamp associated factor","[PAF15_HUMAN|Reviewed]RecName: Full=PCNA-associated factor {ECO:0000305}; AltName: Full=Hepatitis C virus NS5A-transactivated protein 9; Short=HCV NS5A-transactivated protein 9; AltName: Full=Overexpressed in anaplastic thyroid carcinoma 1; Short=OEATC-1; AltName: Full=PCNA-associated factor of 15 kDa; Short=PAF15; Short=p15PAF; AltName: Full=PCNA-clamp-associated factor {ECO:0000312|HGNC:HGNC:28961};+++[G9G6C4_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89543.1}; Flags: Fragment;+++[G9G6D7_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89556.1}; Flags: Fragment;+++[G9G6H1_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89590.1}; Flags: Fragment;+++[H0YKX3_HUMAN|Unreviewed]SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000452975};+++[H0YMA4_HUMAN|Unreviewed]SubName: Full=HCG2039386, isoform CRA_b {ECO:0000313|EMBL:EAW77680.1}; SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000453527};"]
[977,"'CD151'",11532,14655,16372,14186.3333333333,null,"H00928///Nephropathy with pretibial epidermolysis bullosa and deafness",null,null,"GO:0009986///cell surface+++GO:0005925///focal adhesion+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005604///basement membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005178///integrin binding","GO:0044319///wound healing, spreading of cells+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0031581///hemidesmosome assembly+++GO:0016477///cell migration+++GO:0045807///positive regulation of endocytosis+++GO:0030335///positive regulation of cell migration+++GO:0042098///T cell proliferation","CD151 molecule (Raph blood group)","[CD151_HUMAN|Reviewed]RecName: Full=CD151 antigen; AltName: Full=GP27; AltName: Full=Membrane glycoprotein SFA-1; AltName: Full=Platelet-endothelial tetraspan antigen 3; Short=PETA-3; AltName: Full=Tetraspanin-24; Short=Tspan-24; AltName: CD_antigen=CD151;+++[A0A024RCB3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJC8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PJE8_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000433752}; Flags: Fragment;+++[E9PK37_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000431671}; Flags: Fragment;+++[E9PLZ6_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PMR4_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PP93_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000434663}; Flags: Fragment;+++[E9PRJ3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PSA1_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000435854}; Flags: Fragment;+++[K4DIA7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[K4DIB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[Q6ZNZ0_HUMAN|Unreviewed]SubName: Full=CD151 antigen (Raph blood group), isoform CRA_b {ECO:0000313|EMBL:EAX02401.1}; SubName: Full=cDNA FLJ26859 fis, clone PRS08290 {ECO:0000313|EMBL:BAC85335.1};"]
[9770,"'RASSF2'",1060,1095,882,1012.33333333333,"04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species",{"$nulls":3},"GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0000777///condensed chromosome kinetochore","GO:0004672///protein kinase activity+++GO:0005515///protein binding","GO:0038168///epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade+++GO:0001501///skeletal system development+++GO:0042981///regulation of apoptotic process+++GO:0046849///bone remodeling+++GO:0045670///regulation of osteoclast differentiation+++GO:0001503///ossification+++GO:0050821///protein stabilization+++GO:0046330///positive regulation of JNK cascade+++GO:0007049///cell cycle+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:0048872///homeostasis of number of cells+++GO:0006468///protein phosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0045667///regulation of osteoblast differentiation+++GO:0007165///signal transduction+++GO:0043065///positive regulation of apoptotic process","Ras association domain family member 2","[RASF2_HUMAN|Reviewed]RecName: Full=Ras association domain-containing protein 2;"]
[9771,"'RAPGEF5'",123,106,99,109.333333333333,"04015///Rap1 signaling pathway+++04014///Ras signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0030742///GTP-dependent protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0017034///Rap guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0035556///intracellular signal transduction+++GO:0007399///nervous system development+++GO:0007264///small GTPase mediated signal transduction","Rap guanine nucleotide exchange factor 5","[RPGF5_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 5; AltName: Full=Guanine nucleotide exchange factor for Rap1; AltName: Full=M-Ras-regulated Rap GEF; Short=MR-GEF; AltName: Full=Related to Epac; Short=Repac;+++[A0A0S2Z561_HUMAN|Unreviewed]SubName: Full=HCG38228, isoform CRA_b {ECO:0000313|EMBL:EAW93746.1}; SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 2 {ECO:0000313|EMBL:ALQ33949.1}; Flags: Fragment;+++[A0A0S2Z5S1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 1 {ECO:0000313|EMBL:ALQ33948.1}; Flags: Fragment;+++[A8MQ07_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000343656};+++[C9JBS6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000415664}; Flags: Fragment;+++[C9JHM4_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000395729}; Flags: Fragment;+++[E9PGY3_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000384870};+++[F8WD32_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000403956};+++[Q5JPD2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667A016 {ECO:0000313|EMBL:CAI46177.1};"]
[9772,"'TMEM94'",2481,2320,2506,2435.66666666667,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"transmembrane protein 94","[TMM94_HUMAN|Reviewed]RecName: Full=Transmembrane protein 94 {ECO:0000312|HGNC:HGNC:28983};+++[A0A024R8S6_HUMAN|Unreviewed]SubName: Full=KIAA0195, isoform CRA_a {ECO:0000313|EMBL:EAW89275.1};+++[B7Z9U5_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78959, highly similar to Transmembrane protein 94 {ECO:0000313|EMBL:BAH14431.1};+++[C9JL75_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000364397};+++[J3KRN3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462084}; Flags: Fragment;+++[J3KRU7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462170}; Flags: Fragment;+++[J3KS76_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462344};+++[J3KT63_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462821}; Flags: Fragment;+++[J3KTL5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463046}; Flags: Fragment;+++[J3QLC5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463487}; Flags: Fragment;+++[J3QLM7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463620}; Flags: Fragment;+++[J3QQW3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463929};+++[J3QRT3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464370}; Flags: Fragment;+++[J3QRT7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464375}; Flags: Fragment;+++[J3QRY7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464437}; Flags: Fragment;+++[J3QS17_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464479}; Flags: Fragment;+++[J3QS24_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464491}; Flags: Fragment;+++[J3QSG7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464679}; Flags: Fragment;"]
[9774,"'BCLAF1'",1767,1737,1300,1601.33333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:1990830///cellular response to leukemia inhibitory factor+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0043065///positive regulation of apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006915///apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2001022///positive regulation of response to DNA damage stimulus","BCL2 associated transcription factor 1","[BCLF1_HUMAN|Reviewed]RecName: Full=Bcl-2-associated transcription factor 1; Short=Btf; AltName: Full=BCLAF1 and THRAP3 family member 1;+++[A0A1W2PQ43_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000491530};+++[E9PJA7_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433822};+++[E9PK09_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000431734}; Flags: Fragment;+++[E9PK91_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000435441};+++[E9PKI6_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433505};+++[E9PQN2_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436142};+++[H0YF00_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436913}; Flags: Fragment;+++[H0YF14_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437018}; Flags: Fragment;+++[H0YF63_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437333}; Flags: Fragment;+++[Q6DCA8_HUMAN|Unreviewed]SubName: Full=BCLAF1 protein {ECO:0000313|EMBL:AAH78160.1}; Flags: Fragment;"]
[9775,"'EIF4A3'",418,377,493,429.333333333333,"03013///RNA transport+++03015///mRNA surveillance pathway+++03040///Spliceosome",null,"M00430///Exon junction complex (EJC)",null,"GO:0016607///nuclear speck+++GO:1990904///ribonucleoprotein complex+++GO:0043025///neuronal cell body+++GO:0071013///catalytic step 2 spliceosome+++GO:0099524///postsynaptic cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex+++GO:0005681///spliceosomal complex+++GO:0030425///dendrite+++GO:0005634///nucleus","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0008143///poly(A) binding+++GO:0003729///mRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0000166///nucleotide binding","GO:0006364///rRNA processing+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0072715///cellular response to selenite ion+++GO:0035640///exploration behavior+++GO:1902415///regulation of mRNA binding+++GO:0045727///positive regulation of translation+++GO:1904570///negative regulation of selenocysteine incorporation+++GO:0008306///associative learning+++GO:0006406///mRNA export from nucleus+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:1904574///negative regulation of selenocysteine insertion sequence binding+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0008380///RNA splicing+++GO:0031124///mRNA 3'-end processing+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0014070///response to organic cyclic compound+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0010629///negative regulation of gene expression+++GO:0051028///mRNA transport","eukaryotic translation initiation factor 4A3","[IF4A3_HUMAN|Reviewed]RecName: Full=Eukaryotic initiation factor 4A-III; Short=eIF-4A-III; Short=eIF4A-III; EC=3.6.4.13 {ECO:0000269|PubMed:16170325, ECO:0000269|PubMed:17375189, ECO:0000269|PubMed:22961380}; AltName: Full=ATP-dependent RNA helicase DDX48; AltName: Full=ATP-dependent RNA helicase eIF4A-3; AltName: Full=DEAD box protein 48; AltName: Full=Eukaryotic initiation factor 4A-like NUK-34; AltName: Full=Eukaryotic translation initiation factor 4A isoform 3; AltName: Full=Nuclear matrix protein 265; Short=NMP 265; Short=hNMP 265; Contains: RecName: Full=Eukaryotic initiation factor 4A-III, N-terminally processed;+++[A0A024R8W0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 48, isoform CRA_a {ECO:0000313|EMBL:EAW89585.1};+++[I3L3H2_HUMAN|Unreviewed]SubName: Full=Eukaryotic initiation factor 4A-III {ECO:0000313|Ensembl:ENSP00000460439}; Flags: Fragment;"]
[9776,"'ATG13'",2882,3119,3010,3003.66666666667,"04138///Autophagy - yeast+++04136///Autophagy - other+++04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0019898///extrinsic component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane","GO:0019887///protein kinase regulator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0098780///response to mitochondrial depolarisation+++GO:0000422///autophagy of mitochondrion+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0000045///autophagosome assembly+++GO:0016241///regulation of macroautophagy+++GO:0006914///autophagy+++GO:0000423///mitophagy+++GO:0034497///protein localization to phagophore assembly site+++GO:0032147///activation of protein kinase activity+++GO:0016236///macroautophagy","autophagy related 13","[ATG13_HUMAN|Reviewed]RecName: Full=Autophagy-related protein 13;+++[A0A1B0GXJ3_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463808}; Flags: Fragment;+++[A8K0S6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214};+++[E9PPR2_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;+++[H0YCL5_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000431877}; Flags: Fragment;+++[H0YDR0_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000434125}; Flags: Fragment;+++[H0YEM7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000436174}; Flags: Fragment;+++[H0YF43_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000437191}; Flags: Fragment;+++[J3KRU6_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462167}; Flags: Fragment;+++[J3KST9_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462644}; Flags: Fragment;+++[J3QLH7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463550}; Flags: Fragment;+++[J3QR16_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463998}; Flags: Fragment;+++[J3QR83_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464091}; Flags: Fragment;+++[J3QRL1_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464274}; Flags: Fragment;+++[J9JIF6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;"]
[9777,"'TM9SF4'",1992,2043,2069,2034.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04062///Chemokine signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005768///endosome+++GO:0005769///early endosome","GO:0005515///protein binding","GO:0006909///phagocytosis+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0072657///protein localization to membrane+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0051453///regulation of intracellular pH+++GO:0007155///cell adhesion+++GO:0001666///response to hypoxia","transmembrane 9 superfamily member 4","[TM9S4_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 4; AltName: Full=Tumor cannibalism associated protein 1 {ECO:0000303|PubMed:19893578}; Flags: Precursor;+++[A0A024QYR3_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[A0A0C4DFM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[B4DH88_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F2Z2L1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F8WCN2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[9778,"'KIAA0232'",802,822,526,716.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0000166///nucleotide binding+++GO:0005524///ATP binding",null,"KIAA0232","[K0232_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0232;+++[A5YKK5_HUMAN|Unreviewed]SubName: Full=KIAA0232 {ECO:0000313|EMBL:ABQ66267.1};+++[D6REK0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0232 {ECO:0000313|Ensembl:ENSP00000426815};+++[Q9Y349_HUMAN|Unreviewed]SubName: Full=KIAA0232 protein {ECO:0000313|EMBL:CAG33441.1};"]
[9779,"'TBC1D5'",583,588,447,539.333333333333,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0030904///retromer complex+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:1905394///retromer complex binding","GO:0006886///intracellular protein transport+++GO:0016236///macroautophagy+++GO:1902017///regulation of cilium assembly+++GO:0002092///positive regulation of receptor internalization+++GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0006914///autophagy+++GO:0090630///activation of GTPase activity+++GO:0042594///response to starvation","TBC1 domain family member 5","[TBCD5_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 5;+++[A0A024R2H0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_a {ECO:0000313|EMBL:EAW64287.1};+++[A0A024R2J9_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_b {ECO:0000313|EMBL:EAW64288.1};+++[B9A6K1_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5 {ECO:0000313|EMBL:BAH16629.1};+++[C9J397_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000410596}; Flags: Fragment;+++[C9J3F6_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411925};+++[C9JDR8_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396239}; Flags: Fragment;+++[C9JED7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000415379}; Flags: Fragment;+++[C9JIU4_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396850}; Flags: Fragment;+++[C9JMP7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000408603}; Flags: Fragment;+++[C9JNM0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000414159}; Flags: Fragment;+++[C9JW04_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000387395}; Flags: Fragment;+++[C9JWX0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000399967}; Flags: Fragment;+++[C9K0P2_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000393882}; Flags: Fragment;+++[F2Z3C3_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000424998}; Flags: Fragment;+++[F2Z3I5_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411780};"]
[978,"'CDA'",0,3,1,1.33333333333333,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00983///Drug metabolism - other enzymes",null,null,"R08221///5'-deoxy-5-fluorocytidine aminohydrolase   5'-Deoxy-5-fluorocytidine + H2O <=> 5'-Deoxy-5-fluorouridine + Ammonia+++R02485///deoxycytidine aminohydrolase   Deoxycytidine + H2O <=> Deoxyuridine + Ammonia+++R01878///Cytidine aminohydrolase   Cytidine + H2O <=> Uridine + Ammonia","GO:1904813///ficolin-1-rich granule lumen+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:1904724///tertiary granule lumen","GO:0008270///zinc ion binding+++GO:0004126///cytidine deaminase activity+++GO:0042803///protein homodimerization activity+++GO:0003824///catalytic activity+++GO:0001882///nucleoside binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity","GO:0043097///pyrimidine nucleoside salvage+++GO:0030308///negative regulation of cell growth+++GO:0045980///negative regulation of nucleotide metabolic process+++GO:0008655///pyrimidine-containing compound salvage+++GO:0043312///neutrophil degranulation+++GO:0019858///cytosine metabolic process+++GO:0009972///cytidine deamination+++GO:0051289///protein homotetramerization+++GO:0007166///cell surface receptor signaling pathway","cytidine deaminase","[CDD_HUMAN|Reviewed]RecName: Full=Cytidine deaminase; EC=3.5.4.5; AltName: Full=Cytidine aminohydrolase;+++[Q71UE9_HUMAN|Unreviewed]SubName: Full=Cytidine deaminase {ECO:0000313|EMBL:AAC69599.1}; EC=3.5.4.5 {ECO:0000313|EMBL:AAC69599.1}; Flags: Fragment;"]
[9780,"'PIEZO1'",6630,7608,6979,7072.33333333333,null,"H01978///Dehydrated hereditary stomatocytosis+++H02001///Familial pseudohyperkalemia+++H00811///Distal arthrogryposis (DA)+++H00232///Hereditary stomatocytosis (HSt)",null,null,"GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0031258///lamellipodium membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane","GO:0008381///mechanosensitive ion channel activity+++GO:0005261///cation channel activity","GO:0033625///positive regulation of integrin activation+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0042391///regulation of membrane potential+++GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0050982///detection of mechanical stimulus+++GO:0006812///cation transport+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071260///cellular response to mechanical stimulus","piezo type mechanosensitive ion channel component 1","[PIEZ1_HUMAN|Reviewed]RecName: Full=Piezo-type mechanosensitive ion channel component 1; AltName: Full=Membrane protein induced by beta-amyloid treatment; Short=Mib; AltName: Full=Protein FAM38A;+++[E7EUT2_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000333704};+++[H0YB49_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000428673}; Flags: Fragment;+++[H3BRR7_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456373}; Flags: Fragment;+++[H3BSF6_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456680}; Flags: Fragment;+++[H7C2J5_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000406358}; Flags: Fragment;+++[M4QHP2_HUMAN|Unreviewed]RecName: Full=Piezo-type mechanosensitive ion channel component {ECO:0000256|RuleBase:RU362023};+++[Q96HU3_HUMAN|Unreviewed]SubName: Full=FAM38A protein {ECO:0000313|EMBL:AAH08073.2};"]
[9781,"'RNF144A'",58,63,60,60.3333333333333,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0010008///endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding","GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination","ring finger protein 144A","[R144A_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF144A; EC=2.3.2.31 {ECO:0000250|UniProtKB:O60260}; AltName: Full=RING finger protein 144A; AltName: Full=UbcM4-interacting protein 4; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 4;+++[C9JLH4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF144A {ECO:0000313|Ensembl:ENSP00000414420}; Flags: Fragment;+++[H7C3G0_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;"]
[9782,"'MATR3'",3310,3158,2772,3080,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0003676///nucleic acid binding+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0035198///miRNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0002218///activation of innate immune response+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0045087///innate immune response+++GO:0002376///immune system process","matrin 3","[MATR3_HUMAN|Reviewed]RecName: Full=Matrin-3;+++[A0A0R4J2E8_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000354346};+++[A0A1B0GX04_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421145}; Flags: Fragment;+++[A8MXP9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000378279};+++[B3KM87_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10526 fis, clone NT2RP2000931, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG50899.1};+++[B4DF66_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55637, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG57327.1};+++[D6R8Z5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422233}; Flags: Fragment;+++[D6R991_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423290}; Flags: Fragment;+++[D6R9F3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422137}; Flags: Fragment;+++[D6R9N0_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423521}; Flags: Fragment;+++[D6RAM9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421666}; Flags: Fragment;+++[D6RAY2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424646}; Flags: Fragment;+++[D6RB45_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424431}; Flags: Fragment;+++[D6RBI2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422700}; Flags: Fragment;+++[D6RBK5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422649}; Flags: Fragment;+++[D6RBS2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422590}; Flags: Fragment;+++[D6RCM3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427168};+++[D6RE02_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000425150}; Flags: Fragment;+++[D6REK4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426801}; Flags: Fragment;+++[D6REM6_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426743};+++[D6RIA2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427557}; Flags: Fragment;+++[H0Y8T4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422054}; Flags: Fragment;+++[Q68E03_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000480093};+++[Q9H4N1_HUMAN|Unreviewed]SubName: Full=Clone CDABP0107 mRNA sequence {ECO:0000313|EMBL:AAG02007.1};"]
[9783,"'RIMS3'",119,133,98,116.666666666667,{"$nulls":4},"GO:0030054///cell junction+++GO:0016020///membrane+++GO:0042734///presynaptic membrane+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0045202///synapse+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0048786///presynaptic active zone","GO:0017137///Rab GTPase binding+++GO:0044325///ion channel binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0017156///calcium ion regulated exocytosis+++GO:0042391///regulation of membrane potential+++GO:0050806///positive regulation of synaptic transmission+++GO:0048167///regulation of synaptic plasticity+++GO:0006887///exocytosis+++GO:0006836///neurotransmitter transport+++GO:2000300///regulation of synaptic vesicle exocytosis","regulating synaptic membrane exocytosis 3","[RIMS3_HUMAN|Reviewed]RecName: Full=Regulating synaptic membrane exocytosis protein 3; Short=Nim3; AltName: Full=RIM3 gamma; AltName: Full=Rab-3-interacting molecule 3; Short=RIM 3;+++[L8EAQ2_HUMAN|Unreviewed]SubName: Full=Alternative protein RIMS3 {ECO:0000313|EMBL:CCQ43458.1};+++[X5D2V8_HUMAN|Unreviewed]SubName: Full=Regulating synaptic membrane exocytosis 3 isoform C {ECO:0000313|EMBL:AHW56609.1}; Flags: Fragment;"]
[9784,"'SNX17'",1377,1311,1495,1394.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005769///early endosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005768///endosome+++GO:0005623///cell+++GO:0010008///endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0050750///low-density lipoprotein particle receptor binding+++GO:0008289///lipid binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0035091///phosphatidylinositol binding","GO:0006898///receptor-mediated endocytosis+++GO:0016197///endosomal transport+++GO:0003279///cardiac septum development+++GO:0006707///cholesterol catabolic process+++GO:0035904///aorta development+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0015031///protein transport+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0060976///coronary vasculature development+++GO:0006886///intracellular protein transport","sorting nexin 17","[SNX17_HUMAN|Reviewed]RecName: Full=Sorting nexin-17;+++[B4DDM3_HUMAN|Unreviewed]SubName: Full=Sorting nexin 17, isoform CRA_a {ECO:0000313|EMBL:EAX00584.1}; SubName: Full=cDNA FLJ51047, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60979.1}; SubName: Full=cDNA FLJ53821, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG56784.1}; SubName: Full=cDNA FLJ61770, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG58262.1};+++[B4DQ37_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56223, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60799.1};+++[B4DTB8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51699, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG61930.1};+++[F8WAZ0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000405399};+++[F8WEG6_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000401922};+++[F8WFA0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000399727};"]
[9785,"'DHX38'",615,647,612,624.666666666667,"03040///Spliceosome",{"$nulls":3},"GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005681///spliceosomal complex","GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0006405///RNA export from nucleus","DEAH-box helicase 38","[PRP16_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase DHX38; AltName: Full=DEAH box protein 38;+++[B4DM30_HUMAN|Unreviewed]SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 38, isoform CRA_d {ECO:0000313|EMBL:EAW59183.1}; SubName: Full=cDNA FLJ50987, highly similar to Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|EMBL:BAG59742.1};+++[H3BMS7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000454521}; Flags: Fragment;+++[H3BQT9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000455939}; Flags: Fragment;+++[H3BV01_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000457887}; Flags: Fragment;+++[J3KRT1_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462149};+++[J3KSA8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462397}; Flags: Fragment;+++[J3KTG2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462965}; Flags: Fragment;"]
[9786,"'KIAA0586'",317,282,203,267.333333333333,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04140///Autophagy - animal+++04137///Mitophagy - animal","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0036064///ciliary basal body+++GO:0001917///photoreceptor inner segment+++GO:0042995///cell projection+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0019904///protein domain specific binding+++GO:0043021///ribonucleoprotein complex binding+++GO:1990247///N6-methyladenosine-containing RNA binding+++GO:0004857///enzyme inhibitor activity+++GO:1990827///deaminase binding+++GO:0003729///mRNA binding","GO:0070201///regulation of establishment of protein localization+++GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly","KIAA0586","[TALD3_HUMAN|Reviewed]RecName: Full=Protein TALPID3;+++[A0A087WYM5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000481936};+++[B4DYW5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61484 {ECO:0000313|EMBL:BAG63877.1};+++[B7Z7W7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52366 {ECO:0000313|EMBL:BAH13753.1};+++[G3V2T5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000450855}; Flags: Fragment;+++[G3V4J0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451831}; Flags: Fragment;+++[G3V5U9_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000452536};+++[H0YJF0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451356}; Flags: Fragment;+++[L0R885_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0586 {ECO:0000313|EMBL:CCO13756.1};"]
[9787,"'DLGAP5'",5,1,1,2.33333333333333,{"$nulls":4},"GO:0005819///spindle+++GO:0031616///spindle pole centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0023052///signaling+++GO:0006470///protein dephosphorylation+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0008283///cell proliferation+++GO:0007221///positive regulation of transcription of Notch receptor target","DLG associated protein 5","[DLGP5_HUMAN|Reviewed]RecName: Full=Disks large-associated protein 5; Short=DAP-5; AltName: Full=Discs large homolog 7; AltName: Full=Disks large-associated protein DLG7; AltName: Full=Hepatoma up-regulated protein; Short=HURP;+++[G3V4E5_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000451747}; Flags: Fragment;+++[G3V543_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000452168};"]
[9788,"'MTSS1'",1171,596,615,794,"00190///Oxidative phosphorylation+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease+++01100///Metabolic pathways+++05016///Huntington's disease+++05010///Alzheimer's disease+++04714///Thermogenesis+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04723///Retrograde endocannabinoid signaling","H00473///Mitochondrial complex I deficiency","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0030139///endocytic vesicle","GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding","GO:0072160///nephron tubule epithelial cell differentiation+++GO:0072102///glomerulus morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007009///plasma membrane organization+++GO:0071498///cellular response to fluid shear stress+++GO:0030035///microspike assembly+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis+++GO:0061333///renal tubule morphogenesis","MTSS1, I-BAR domain containing","[MTSS1_HUMAN|Reviewed]RecName: Full=Metastasis suppressor protein 1; AltName: Full=Metastasis suppressor YGL-1; AltName: Full=Missing in metastasis protein;+++[A5YM41_HUMAN|Unreviewed]SubName: Full=MTSS1 protein {ECO:0000313|EMBL:ABQ59025.1};+++[E5RJX3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428145}; Flags: Fragment;+++[E7EWW5_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428319};+++[H0YAZ8_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428348}; Flags: Fragment;+++[H0YB53_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428685}; Flags: Fragment;+++[H0YBL3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000429752}; Flags: Fragment;"]
[9789,"'SPCS2'",633,552,651,612,"03060///Protein export",null,null,"R04018///Acylneuraminyl hydrolase Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O","GO:0005787///signal peptidase complex+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0031090///organelle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005783///endoplasmic reticulum","GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0045047///protein targeting to ER","signal peptidase complex subunit 2","[SPCS2_HUMAN|Reviewed]RecName: Full=Signal peptidase complex subunit 2; EC=3.4.-.-; AltName: Full=Microsomal signal peptidase 25 kDa subunit; Short=SPase 25 kDa subunit;+++[A0A087WUC6_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000478550};+++[E9PI68_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000436759};+++[E9PL01_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000433439};+++[E9PRB9_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434248};+++[H0YE04_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434706}; Flags: Fragment;"]
[9790,"'BMS1'",761.99,824.37,744.33,776.896666666667,"03008///Ribosome biogenesis in eukaryotes","H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0030686///90S preribosome+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0034511///U3 snoRNA binding+++GO:0000166///nucleotide binding","GO:0042254///ribosome biogenesis+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","BMS1, ribosome biogenesis factor","[BMS1_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;"]
[9791,"'PTDSS1'",918,849,787,851.333333333333,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways","H01832///Lenz-Majewski syndrome",null,"R07377///Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006659///phosphatidylserine biosynthetic process","phosphatidylserine synthase 1","[PTSS1_HUMAN|Reviewed]RecName: Full=Phosphatidylserine synthase 1; Short=PSS-1; Short=PtdSer synthase 1; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme I;+++[J3KNR6_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 1, isoform CRA_a {ECO:0000313|EMBL:EAW91753.1};+++[Q9BSY0_HUMAN|Unreviewed]SubName: Full=PTDSS1 protein {ECO:0000313|EMBL:AAH04502.2}; Flags: Fragment;"]
[9792,"'SERTAD2'",814,684,442,646.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003713///transcription coactivator activity","GO:0030308///negative regulation of cell growth+++GO:0045893///positive regulation of transcription, DNA-templated","SERTA domain containing 2","[SRTD2_HUMAN|Reviewed]RecName: Full=SERTA domain-containing protein 2; AltName: Full=Transcriptional regulator interacting with the PHD-bromodomain 2; Short=TRIP-Br2;"]
[9793,"'CKAP5'",1532,1658,1260,1483.33333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000776///kinetochore+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0000930///gamma-tubulin complex+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore+++GO:0005813///centrosome+++GO:0000922///spindle pole+++GO:0005886///plasma membrane+++GO:0005694///chromosome+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0032991///protein-containing complex+++GO:0005730///nucleolus+++GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end","GO:0051010///microtubule plus-end binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007098///centrosome cycle+++GO:0007019///microtubule depolymerization+++GO:0051301///cell division+++GO:0051298///centrosome duplication+++GO:0050658///RNA transport+++GO:0007051///spindle organization+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0046785///microtubule polymerization+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007049///cell cycle","cytoskeleton associated protein 5","[CKAP5_HUMAN|Reviewed]RecName: Full=Cytoskeleton-associated protein 5; AltName: Full=Colonic and hepatic tumor overexpressed gene protein; Short=Ch-TOG;+++[E9PQH5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436769}; Flags: Fragment;+++[H0YCF6_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000431509}; Flags: Fragment;+++[H0YDX5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000434523}; Flags: Fragment;+++[H0YEK7_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436052}; Flags: Fragment;+++[Q8IYN5_HUMAN|Unreviewed]SubName: Full=CKAP5 protein {ECO:0000313|EMBL:AAH35554.1};"]
[9794,"'MAML1'",969,967,856,930.666666666667,"04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05165///Human papillomavirus infection","H01508///Salivary gland cancer",null,null,"GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042605///peptide antigen binding+++GO:0019901///protein kinase binding","GO:0045445///myoblast differentiation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0010831///positive regulation of myotube differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0003162///atrioventricular node development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0060928///atrioventricular node cell development","mastermind like transcriptional coactivator 1","[MAML1_HUMAN|Reviewed]RecName: Full=Mastermind-like protein 1; Short=Mam-1;"]
[9796,"'PHYHIP'",108,186,154,149.333333333333,"04623///Cytosolic DNA-sensing pathway+++01100///Metabolic pathways+++04137///Mitophagy - animal+++05169///Epstein-Barr virus infection+++00230///Purine metabolism+++00240///Pyrimidine metabolism+++04140///Autophagy - animal+++03020///RNA polymerase",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA ATP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA CTP + RNA <=> Diphosphate + RNA","GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0016607///nuclear speck","GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0045089///positive regulation of innate immune response","phytanoyl-CoA 2-hydroxylase interacting protein","[PHYIP_HUMAN|Reviewed]RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein; AltName: Full=Phytanoyl-CoA hydroxylase-associated protein 1; Short=PAHX-AP1; Short=PAHXAP1;+++[E5RHN5_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA hydroxylase-interacting protein {ECO:0000313|Ensembl:ENSP00000430870}; Flags: Fragment;"]
[9797,"'TATDN2'",818,706,700,741.333333333333,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0004518///nuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters","GO:0006259///DNA metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0036498///IRE1-mediated unfolded protein response","TatD DNase domain containing 2","[TATD2_HUMAN|Reviewed]RecName: Full=Putative deoxyribonuclease TATDN2; EC=3.1.21.-;+++[A0A024R2F3_HUMAN|Unreviewed]SubName: Full=TatD DNase domain containing 2, isoform CRA_a {ECO:0000313|EMBL:EAW64071.1};+++[H7BZJ2_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN2 {ECO:0000313|Ensembl:ENSP00000389896}; Flags: Fragment;"]
[9798,"'IST1'",1006,1089,1003,1032.66666666667,"04144///Endocytosis",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005737///cytoplasm+++GO:0005635///nuclear envelope+++GO:0005856///cytoskeleton+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0035578///azurophil granule lumen","GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding+++GO:0090541///MIT domain binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061640///cytoskeleton-dependent cytokinesis+++GO:0043312///neutrophil degranulation+++GO:0036258///multivesicular body assembly+++GO:1904903///ESCRT III complex disassembly+++GO:0048672///positive regulation of collateral sprouting+++GO:0051301///cell division+++GO:0019076///viral release from host cell+++GO:0045184///establishment of protein localization+++GO:0009838///abscission+++GO:0008104///protein localization+++GO:0046745///viral capsid secondary envelopment+++GO:0045862///positive regulation of proteolysis+++GO:0015031///protein transport+++GO:0007049///cell cycle","IST1, ESCRT-III associated factor","[IST1_HUMAN|Reviewed]RecName: Full=IST1 homolog; Short=hIST1; AltName: Full=Putative MAPK-activating protein PM28;+++[B4DXC9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59095 {ECO:0000313|EMBL:BAG63341.1};+++[E9PF00_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000410081};+++[F5GXM3_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000398505}; Flags: Fragment;+++[H3BMU1_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000454541}; Flags: Fragment;+++[H3BPP6_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455409}; Flags: Fragment;+++[H3BQ38_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455590}; Flags: Fragment;+++[H3BQF7_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455757}; Flags: Fragment;+++[H3BRE2_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000456200}; Flags: Fragment;+++[H3BUI0_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000457646}; Flags: Fragment;+++[J3KR23_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000414942}; Flags: Fragment;+++[J3QQP8_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000463833};"]
[98,"'ACYP2'",223,209,201,211,"00627///Aminobenzoate degradation+++01120///Microbial metabolism in diverse environments+++00620///Pyruvate metabolism",null,null,"R00317///Acetyl phosphate phosphohydrolase   Acetyl phosphate + H2O <=> Acetate + Orthophosphate+++R01515///3-Phospho-D-glyceroyl phosphate phosphohydrolase   3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate+++R01421///Benzoyl phosphate phosphohydrolase   Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate","GO:0005623///cell+++GO:1990111///spermatoproteasome complex+++GO:0017053///transcriptional repressor complex+++GO:0035868///alphav-beta3 integrin-HMGB1 complex+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005839///proteasome core complex+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000793///condensed chromosome+++GO:0070062///extracellular exosome","GO:0042802///identical protein binding+++GO:0003998///acylphosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0006796///phosphate-containing compound metabolic process","acylphosphatase 2","[ACYP2_HUMAN|Reviewed]RecName: Full=Acylphosphatase-2; EC=3.6.1.7; AltName: Full=Acylphosphatase, muscle type isozyme; AltName: Full=Acylphosphate phosphohydrolase 2;+++[A0A140VJD7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[D6W5B6_HUMAN|Unreviewed]SubName: Full=Acylphosphatase 2, muscle type, isoform CRA_a {ECO:0000313|EMBL:EAX00155.1};+++[E9PF46_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[F8WA34_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[Q4ZFV7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ACYP2 {ECO:0000313|EMBL:AAX88874.1}; Flags: Fragment;+++[Q53TK7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX1_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX8_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475333};+++[U3KQ09_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475424};+++[U3KQ94_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475658}; SubName: Full=HCG2040114, isoform CRA_a {ECO:0000313|EMBL:EAX00159.1};+++[U3KQL2_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520};"]
[9801,"'MRPL19'",402,293,280,325,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0015934///large ribosomal subunit+++GO:0005840///ribosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0031965///nuclear membrane","GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006412///translation+++GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:1990830///cellular response to leukemia inhibitory factor","mitochondrial ribosomal protein L19","[RM19_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L19, mitochondrial; Short=L19mt; Short=MRP-L19; AltName: Full=39S ribosomal protein L15, mitochondrial; Short=L15mt; Short=MRP-L15; AltName: Full=Mitochondrial large ribosomal subunit protein bL19m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[A0A0A0MRF4_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000351639};+++[H7C2J0_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000406267}; Flags: Fragment;+++[S4R3W9_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000474821}; Flags: Fragment;+++[S4R455_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000475090}; Flags: Fragment;"]
[9802,"'DAZAP2'",2951,2893,3198,3014,{"$nulls":4},"GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0030971///receptor tyrosine kinase binding+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding","GO:0071902///positive regulation of protein serine/threonine kinase activity","DAZ associated protein 2","[DAZP2_HUMAN|Reviewed]RecName: Full=DAZ-associated protein 2; AltName: Full=Deleted in azoospermia-associated protein 2;+++[A0A024R110_HUMAN|Unreviewed]SubName: Full=DAZ associated protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW58182.1};+++[E9PE89_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000404968};+++[F8VUW5_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000447842};+++[S4R3Q0_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000474597};"]
[9804,"'TOMM20'",1784,1699,1665,1716,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005740///mitochondrial envelope+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0005741///mitochondrial outer membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0030943///mitochondrion targeting sequence binding+++GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051082///unfolded protein binding","GO:0016031///tRNA import into mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006626///protein targeting to mitochondrion+++GO:0006886///intracellular protein transport+++GO:0014850///response to muscle activity+++GO:0016579///protein deubiquitination+++GO:1905242///response to 3,3',5-triiodo-L-thyronine+++GO:0006605///protein targeting+++GO:0015031///protein transport+++GO:0070096///mitochondrial outer membrane translocase complex assembly","translocase of outer mitochondrial membrane 20","[TOM20_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM20 homolog; AltName: Full=Mitochondrial 20 kDa outer membrane protein; AltName: Full=Outer mitochondrial membrane receptor Tom20;+++[A0A024R3W2_HUMAN|Unreviewed]SubName: Full=Translocase of outer mitochondrial membrane 20 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW70004.1};"]
[9805,"'SCRN1'",2781,2915,2265,2653.66666666667,{"$nulls":4},"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016805///dipeptidase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0006887///exocytosis+++GO:0006508///proteolysis","secernin 1","[SCRN1_HUMAN|Reviewed]RecName: Full=Secernin-1;+++[A0A024RA21_HUMAN|Unreviewed]SubName: Full=Secernin 1, isoform CRA_a {ECO:0000313|EMBL:EAW93927.1};+++[A0A090N7T9_HUMAN|Unreviewed]SubName: Full=Secernin 1 {ECO:0000313|EMBL:EAL24458.1};+++[B8ZZP4_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000387052};+++[C9J7U9_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000406289}; Flags: Fragment;+++[C9K052_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000413184}; Flags: Fragment;"]
[9806,"'SPOCK2'",69,34,51,51.3333333333333,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix","GO:0005509///calcium ion binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0050840///extracellular matrix binding+++GO:0005539///glycosaminoglycan binding+++GO:0005518///collagen binding","GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0010951///negative regulation of endopeptidase activity+++GO:2000147///positive regulation of cell motility+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0007416///synapse assembly+++GO:0045595///regulation of cell differentiation+++GO:0030198///extracellular matrix organization","SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2","[TICN2_HUMAN|Reviewed]RecName: Full=Testican-2; AltName: Full=SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2; Flags: Precursor;+++[A0A024QZQ5_HUMAN|Unreviewed]SubName: Full=Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (Testican) 2, isoform CRA_b {ECO:0000313|EMBL:EAW54443.1};+++[F5H283_HUMAN|Unreviewed]SubName: Full=Testican-2 {ECO:0000313|Ensembl:ENSP00000439445};+++[L8E8K3_HUMAN|Unreviewed]SubName: Full=Alternative protein SPOCK2 {ECO:0000313|EMBL:CCQ43459.1};"]
[9807,"'IP6K1'",1153,1053,1068,1091.33333333333,"04138///Autophagy - yeast+++04070///Phosphatidylinositol signaling system",null,null,"R10548///ATP:1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 5-phosphotransferase   ATP + 1-Diphosinositol pentakisphosphate <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate+++R09087///ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase   ATP + Phytic acid <=> ADP + 5-PP-InsP5","GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0052839///inositol diphosphate tetrakisphosphate kinase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0000829///inositol heptakisphosphate kinase activity+++GO:0016301///kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity+++GO:0005524///ATP binding+++GO:0052836///inositol 5-diphosphate pentakisphosphate 5-kinase activity","GO:0043647///inositol phosphate metabolic process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0016310///phosphorylation","inositol hexakisphosphate kinase 1","[IP6K1_HUMAN|Reviewed]RecName: Full=Inositol hexakisphosphate kinase 1; Short=InsP6 kinase 1; EC=2.7.4.21; AltName: Full=Inositol hexaphosphate kinase 1;+++[A0A024R2X2_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[C9JNA8_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[L8EAR7_HUMAN|Unreviewed]SubName: Full=Alternative protein IP6K1 {ECO:0000313|EMBL:CCQ43876.1};"]
[9810,"'RNF40'",2730,2722,2922,2791.33333333333,{"$nulls":4},"GO:0033503///HULC complex+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0005634///nucleus+++GO:0000151///ubiquitin ligase complex+++GO:0043679///axon terminus+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0017075///syntaxin-1 binding+++GO:0042803///protein homodimerization activity","GO:0043434///response to peptide hormone+++GO:0016567///protein ubiquitination+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0007346///regulation of mitotic cell cycle+++GO:0006325///chromatin organization+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0033523///histone H2B ubiquitination+++GO:0010390///histone monoubiquitination","ring finger protein 40","[BRE1B_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase BRE1B; Short=BRE1-B; EC=2.3.2.27 {ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:19410543}; AltName: Full=95 kDa retinoblastoma-associated protein; Short=RBP95; AltName: Full=RING finger protein 40; AltName: Full=RING-type E3 ubiquitin transferase BRE1B {ECO:0000305};+++[A0A087WTK2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A0A0S2Z4Z2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[A0A0S2Z537_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A8K6K1_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BP71_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BQ99_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BS50_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BUL6_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[I3L332_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[R4GN66_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase BRE1B {ECO:0000313|Ensembl:ENSP00000473507}; Flags: Fragment;"]
[9811,"'CTIF'",1614,1540,1490,1548,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0008494///translation activator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045727///positive regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006417///regulation of translation","cap binding complex dependent translation initiation factor","[CTIF_HUMAN|Reviewed]RecName: Full=CBP80/20-dependent translation initiation factor;+++[A0A024R259_HUMAN|Unreviewed]SubName: Full=KIAA0427, isoform CRA_a {ECO:0000313|EMBL:EAW62927.1};+++[K7EK08_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000465405}; Flags: Fragment;+++[K7EPK6_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467425}; Flags: Fragment;+++[K7EQS5_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467957}; Flags: Fragment;+++[K7EQS9_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467965}; Flags: Fragment;"]
[9812,"'DELE1'",1159,1145,1005,1103,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00606///Early infantile epileptic encephalopathy+++H01775///PCDH19-related epilepsy syndrome",null,null,"GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process","DAP3 binding cell death enhancer 1","[DELE1_HUMAN|Reviewed]RecName: Full=DAP3-binding cell death enhancer 1 {ECO:0000312|HGNC:HGNC:28969}; AltName: Full=Death ligand signal enhancer {ECO:0000303|PubMed:20563667}; Flags: Precursor;+++[D6RBI8_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000422686}; Flags: Fragment;+++[H0YA48_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000426138}; Flags: Fragment;"]
[9813,"'EFCAB14'",2181,1953,1519,1884.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding",null,"EF-hand calcium binding domain 14","[EFC14_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 14;+++[S4R3Q1_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000474599}; Flags: Fragment;"]
[9814,"'SFI1'",174.01,171.88,169.62,171.836666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005814///centriole","GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0005515///protein binding+++GO:0004609///phosphatidylserine decarboxylase activity+++GO:0019902///phosphatase binding","GO:0006629///lipid metabolic process+++GO:0010923///negative regulation of phosphatase activity+++GO:0016540///protein autoprocessing+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0008654///phospholipid biosynthetic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0000086///G2/M transition of mitotic cell cycle","SFI1 centrin binding protein","[SFI1_HUMAN|Reviewed]RecName: Full=Protein SFI1 homolog; Short=hSFI1;+++[A0A024R1K2_HUMAN|Unreviewed]SubName: Full=Sfi1 homolog, spindle assembly associated (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW59983.1};+++[D3YTJ2_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000401199};+++[E5RJU6_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000430488};+++[H0Y5I7_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000398871}; Flags: Fragment;+++[H0Y836_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000416931}; Flags: Fragment;+++[H7BZF3_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000389364}; Flags: Fragment;+++[H7C2F1_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000405541}; Flags: Fragment;+++[X6RJF9_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000411793}; Flags: Fragment;"]
[9815,"'GIT2'",1291,1265,1087,1214.33333333333,"04144///Endocytosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation","GIT ArfGAP 2","[GIT2_HUMAN|Reviewed]RecName: Full=ARF GTPase-activating protein GIT2; Short=ARF GAP GIT2; AltName: Full=Cool-interacting tyrosine-phosphorylated protein 2; Short=CAT-2; Short=CAT2; AltName: Full=G protein-coupled receptor kinase-interactor 2; AltName: Full=GRK-interacting protein 2;+++[A0A024RBI8_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase interactor 2, isoform CRA_a {ECO:0000313|EMBL:EAW97886.1};+++[B5BU58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70108.1};+++[F8VXI9_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000448832};+++[F8W822_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000323833};+++[F8WAK2_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000346585};+++[Q68DM7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G01261 {ECO:0000313|EMBL:CAH18193.1}; Flags: Fragment;+++[Q6FI58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70242.1}; SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 variant {ECO:0000313|EMBL:BAD96456.1}; SubName: Full=GIT2 protein {ECO:0000313|EMBL:CAG38599.1};+++[R4GNG3_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000473637}; Flags: Fragment;"]
[9816,"'URB2'",138,135,126,133,{"$nulls":4},"GO:0030496///midbody+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016235///aggresome",null,"GO:0042254///ribosome biogenesis","URB2 ribosome biogenesis homolog","[URB2_HUMAN|Reviewed]RecName: Full=Unhealthy ribosome biogenesis protein 2 homolog;+++[Q5VYD0_HUMAN|Unreviewed]SubName: Full=Unhealthy ribosome biogenesis protein 2 homolog {ECO:0000313|Ensembl:ENSP00000395107}; Flags: Fragment;+++[Q6PCC8_HUMAN|Unreviewed]SubName: Full=URB2 protein {ECO:0000313|EMBL:AAH59381.1}; Flags: Fragment;"]
[9817,"'KEAP1'",1031,1224,1055,1103.33333333333,"05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04120///Ubiquitin mediated proteolysis+++05225///Hepatocellular carcinoma","H00048///Hepatocellular carcinoma",null,null,"GO:0005884///actin filament+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0030496///midbody+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0042802///identical protein binding+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043687///post-translational protein modification+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0071353///cellular response to interleukin-4+++GO:0016032///viral process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0016567///protein ubiquitination+++GO:0045604///regulation of epidermal cell differentiation","kelch like ECH associated protein 1","[KEAP1_HUMAN|Reviewed]RecName: Full=Kelch-like ECH-associated protein 1; AltName: Full=Cytosolic inhibitor of Nrf2; Short=INrf2; AltName: Full=Kelch-like protein 19;+++[A0A024R7C0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW84112.1};+++[K7EJ49_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465024}; Flags: Fragment;+++[K7EJD8_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465126}; Flags: Fragment;+++[K7EMY1_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000466704}; Flags: Fragment;+++[K7EPZ3_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000467601}; Flags: Fragment;+++[K7EQX2_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468014}; Flags: Fragment;+++[K7ESE0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468671}; Flags: Fragment;"]
[9818,"'NUP58'",551,442,334,442.333333333333,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005643///nuclear pore+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0015031///protein transport+++GO:0006913///nucleocytoplasmic transport+++GO:0006406///mRNA export from nucleus+++GO:0016032///viral process+++GO:0051260///protein homooligomerization+++GO:0051028///mRNA transport+++GO:0042306///regulation of protein import into nucleus+++GO:0051290///protein heterotetramerization+++GO:0051291///protein heterooligomerization+++GO:0070208///protein heterotrimerization","nucleoporin 58","[NUP58_HUMAN|Reviewed]RecName: Full=Nucleoporin p58/p45 {ECO:0000305}; AltName: Full=58 kDa nucleoporin {ECO:0000312|HGNC:HGNC:20261}; AltName: Full=Nucleoporin-like protein 1;+++[F8WBZ1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418244};+++[F8WC35_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418904};+++[F8WCJ8_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418341};+++[H7BYF2_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000371166}; Flags: Fragment;+++[Q5JRG1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000408147}; Flags: Fragment;"]
[9819,"'TSC22D2'",605,712,467,594.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006970///response to osmotic stress","TSC22 domain family member 2","[T22D2_HUMAN|Reviewed]RecName: Full=TSC22 domain family protein 2; AltName: Full=TSC22-related-inducible leucine zipper protein 4;+++[B4DN36_HUMAN|Unreviewed]SubName: Full=TSC22 domain family, member 2, isoform CRA_d {ECO:0000313|EMBL:EAW78841.1}; SubName: Full=cDNA FLJ51900, highly similar to TSC22 domain family protein 2 {ECO:0000313|EMBL:BAG60098.1};+++[H0Y865_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000417747}; Flags: Fragment;+++[H0Y8E9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000420689}; Flags: Fragment;+++[H7C4U3_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000418149}; Flags: Fragment;"]
[9820,"'CUL7'",1318,1169,1172,1219.66666666667,"04120///Ubiquitin mediated proteolysis","H00509///3M syndrome",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005680///anaphase-promoting complex+++GO:1990393///3M complex+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0007030///Golgi organization+++GO:0006508///proteolysis+++GO:0001890///placenta development+++GO:0000226///microtubule cytoskeleton organization+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001570///vasculogenesis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0007088///regulation of mitotic nuclear division+++GO:0001837///epithelial to mesenchymal transition+++GO:0000281///mitotic cytokinesis+++GO:0016567///protein ubiquitination+++GO:0016032///viral process","cullin 7","[CUL7_HUMAN|Reviewed]RecName: Full=Cullin-7; Short=CUL-7;+++[L8E835_HUMAN|Unreviewed]SubName: Full=Alternative protein CUL7 {ECO:0000313|EMBL:CCQ43460.1};"]
[9821,"'RB1CC1'",884,975,739,866,"04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0034045///phagophore assembly site membrane+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000407///phagophore assembly site+++GO:0005789///endoplasmic reticulum membrane+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0019898///extrinsic component of membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0007507///heart development+++GO:0043066///negative regulation of apoptotic process+++GO:0000045///autophagosome assembly+++GO:0030242///autophagy of peroxisome+++GO:0001934///positive regulation of protein phosphorylation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0001889///liver development+++GO:0000422///autophagy of mitochondrion+++GO:0016241///regulation of macroautophagy+++GO:0061709///reticulophagy+++GO:0006914///autophagy+++GO:0007049///cell cycle+++GO:0061723///glycophagy+++GO:0016236///macroautophagy+++GO:0045793///positive regulation of cell size+++GO:0046330///positive regulation of JNK cascade","RB1 inducible coiled-coil 1","[RBCC1_HUMAN|Reviewed]RecName: Full=RB1-inducible coiled-coil protein 1; AltName: Full=FAK family kinase-interacting protein of 200 kDa; Short=FIP200;+++[E5RH44_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429918}; Flags: Fragment;+++[E5RH63_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429879}; Flags: Fragment;+++[E5RHX0_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429611}; Flags: Fragment;+++[E5RJC1_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429115};+++[H0YC28_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430792}; Flags: Fragment;+++[H0YC30_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430809}; Flags: Fragment;"]
[9823,"'ARMCX2'",778,756,709,747.666666666667,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane",null,"GO:0034613///cellular protein localization+++GO:0045944///positive regulation of transcription by RNA polymerase II","armadillo repeat containing X-linked 2","[ARMX2_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 2; AltName: Full=ARM protein lost in epithelial cancers on chromosome X 2; Short=Protein ALEX2;+++[A0A024RCG7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2, isoform CRA_a {ECO:0000313|EMBL:EAX02889.1};+++[A0A0B4J1X4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000393778}; Flags: Fragment;+++[A0A1B0GXK8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000415490}; Flags: Fragment;+++[A8K5M7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76303, highly similar to Homo sapiens armadillo repeat containing, X-linked 2 (ARMCX2), mRNA {ECO:0000313|EMBL:BAF84031.1};+++[Q5H9D7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42024.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000405376}; Flags: Fragment;+++[Q5H9D8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42023.1}; Flags: Fragment;+++[Q5H9E0_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42021.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000410151}; Flags: Fragment;+++[Q5H9E1_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42020.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000412481}; Flags: Fragment;"]
[9824,"'ARHGAP11A'",79.95,59.62,52,63.8566666666667,{"$nulls":4},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction","Rho GTPase activating protein 11A","[RHGBA_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 11A; AltName: Full=Rho-type GTPase-activating protein 11A;+++[A0A2X0SFK9_HUMAN|Unreviewed]SubName: Full=ARHGAP11A {ECO:0000313|EMBL:SPT35684.1}; Flags: Fragment;+++[H3BQ41_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000455593}; Flags: Fragment;+++[H3BR51_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000456078};"]
[9825,"'SPATA2'",346,390,379,371.666666666667,"04217///Necroptosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007283///spermatogenesis+++GO:0012501///programmed cell death+++GO:0007275///multicellular organism development+++GO:0050727///regulation of inflammatory response+++GO:0060544///regulation of necroptotic process+++GO:1990108///protein linear deubiquitination+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0070536///protein K63-linked deubiquitination","spermatogenesis associated 2","[SPAT2_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 2 {ECO:0000303|PubMed:27307491, ECO:0000303|PubMed:27458237};+++[A8K0S9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78311, highly similar to Homo sapiens spermatogenesis associated 2 (SPATA2), mRNA {ECO:0000313|EMBL:BAF82333.1};+++[B4DID4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50158, highly similar to Spermatogenesis-associated protein 2 {ECO:0000313|EMBL:BAG58446.1};+++[L8E7J6_HUMAN|Unreviewed]SubName: Full=Alternative protein SPATA2 {ECO:0000313|EMBL:CCQ43104.1};"]
[9826,"'ARHGEF11'",1327,1123,1125,1191.66666666667,"05200///Pathways in cancer+++04928///Parathyroid hormone synthesis, secretion and action+++04270///Vascular smooth muscle contraction+++05163///Human cytomegalovirus infection",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0030010///establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0006941///striated muscle contraction+++GO:0001558///regulation of cell growth+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","Rho guanine nucleotide exchange factor 11","[ARHGB_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 11; AltName: Full=PDZ-RhoGEF;+++[A0A2X0SFB0_HUMAN|Unreviewed]SubName: Full=ARHGEF11 {ECO:0000313|EMBL:SPT35722.1}; Flags: Fragment;"]
[9827,"'RGP1'",320,325,255,300,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0034066///RIC1-RGP1 guanyl-nucleotide exchange factor complex+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0032588///trans-Golgi network membrane+++GO:0000139///Golgi membrane+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0017137///Rab GTPase binding","GO:1903363///negative regulation of cellular protein catabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0042147///retrograde transport, endosome to Golgi","RGP1 homolog, RAB6A GEF complex partner 1","[RGP1_HUMAN|Reviewed]RecName: Full=RAB6A-GEF complex partner protein 2 {ECO:0000305}; AltName: Full=Retrograde Golgi transport protein RGP1 homolog {ECO:0000250|UniProtKB:P16664};+++[A8K0K1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76996 {ECO:0000313|EMBL:BAF82255.1};"]
[9828,"'ARHGEF17'",2259,2465,2028,2250.66666666667,{"$nulls":4},"GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","Rho guanine nucleotide exchange factor 17","[ARHGH_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 17; AltName: Full=164 kDa Rho-specific guanine-nucleotide exchange factor; Short=p164-RhoGEF; Short=p164RhoGEF; AltName: Full=Tumor endothelial marker 4;+++[A0A2R8Y4D7_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000493940};+++[A0A2X0TVV1_HUMAN|Unreviewed]SubName: Full=ARHGEF17 {ECO:0000313|EMBL:SPT35726.1}; Flags: Fragment;+++[H0YFZ8_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000441135}; Flags: Fragment;"]
[9829,"'DNAJC6'",242,202,161,201.666666666667,"04144///Endocytosis",{"$nulls":3},"GO:0045202///synapse+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0030276///clathrin binding+++GO:0017124///SH3 domain binding+++GO:0004725///protein tyrosine phosphatase activity","GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0061024///membrane organization+++GO:0006470///protein dephosphorylation+++GO:0072583///clathrin-dependent endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:0072318///clathrin coat disassembly+++GO:0035335///peptidyl-tyrosine dephosphorylation","DnaJ heat shock protein family (Hsp40) member C6","[AUXI_HUMAN|Reviewed]RecName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000305}; EC=3.1.3.48; AltName: Full=DnaJ homolog subfamily C member 6 {ECO:0000312|HGNC:HGNC:15469};+++[L0N9S0_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily C, member 6 {ECO:0000313|EMBL:CCE46052.1}; Flags: Fragment;+++[S4R305_HUMAN|Unreviewed]SubName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000313|Ensembl:ENSP00000473821}; Flags: Fragment;"]
[983,"'CDK1'",9,7,6,7.33333333333333,"05168///Herpes simplex infection+++05203///Viral carcinogenesis+++04114///Oocyte meiosis+++04540///Gap junction+++04110///Cell cycle+++05169///Epstein-Barr virus infection+++04218///Cellular senescence+++04914///Progesterone-mediated oocyte maturation+++04115///p53 signaling pathway",null,"M00693///Cell cycle - G2/M transition",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005813///centrosome+++GO:0070062///extracellular exosome+++GO:0005876///spindle microtubule+++GO:0030496///midbody+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005654///nucleoplasm+++GO:0097125///cyclin B1-CDK1 complex+++GO:0072686///mitotic spindle+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0035173///histone kinase activity+++GO:0005524///ATP binding+++GO:0030544///Hsp70 protein binding+++GO:0016740///transferase activity+++GO:0003682///chromatin binding+++GO:0001618///virus receptor activity+++GO:0000166///nucleotide binding+++GO:0097472///cyclin-dependent protein kinase activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0000187///activation of MAPK activity+++GO:0007344///pronuclear fusion+++GO:0014070///response to organic cyclic compound+++GO:0006468///protein phosphorylation+++GO:0030855///epithelial cell differentiation+++GO:0030261///chromosome condensation+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0014038///regulation of Schwann cell differentiation+++GO:0016572///histone phosphorylation+++GO:0046688///response to copper ion+++GO:0018105///peptidyl-serine phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0010628///positive regulation of gene expression+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0016477///cell migration+++GO:0006915///apoptotic process+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0065003///protein-containing complex assembly+++GO:0008283///cell proliferation+++GO:0045995///regulation of embryonic development+++GO:0044772///mitotic cell cycle phase transition+++GO:0016579///protein deubiquitination+++GO:0045471///response to ethanol+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0048678///response to axon injury+++GO:0031100///animal organ regeneration+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0014075///response to amine+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0045740///positive regulation of DNA replication+++GO:0007077///mitotic nuclear envelope disassembly+++GO:0007569///cell aging+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0006260///DNA replication+++GO:0007098///centrosome cycle+++GO:0051301///cell division+++GO:0090166///Golgi disassembly+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0010243///response to organonitrogen compound+++GO:0070301///cellular response to hydrogen peroxide+++GO:0034501///protein localization to kinetochore+++GO:0042493///response to drug+++GO:0006281///DNA repair+++GO:0043066///negative regulation of apoptotic process+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0046718///viral entry into host cell+++GO:0000278///mitotic cell cycle+++GO:1905448///positive regulation of mitochondrial ATP synthesis coupled electron transport+++GO:0033160///positive regulation of protein import into nucleus, translocation+++GO:0046686///response to cadmium ion+++GO:0055015///ventricular cardiac muscle cell development+++GO:0009636///response to toxic substance+++GO:0016310///phosphorylation+++GO:0014823///response to activity","cyclin dependent kinase 1","[CDK1_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 1; Short=CDK1; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cell division control protein 2 homolog; AltName: Full=Cell division protein kinase 1; AltName: Full=p34 protein kinase;+++[A0A024QZJ8_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2, G1 to S and G2 to M, isoform CRA_c {ECO:0000313|EMBL:EAW54207.1};+++[A0A024QZP7_HUMAN|Unreviewed]SubName: Full=Cell division cycle 2, G1 to S and G2 to M, isoform CRA_a {ECO:0000313|EMBL:EAW54209.1}; SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000397973};+++[A0A087WZZ9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000482996};+++[B7Z3D6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50170, highly similar to Cell division control protein 2 homolog {ECO:0000313|EMBL:BAH12172.1};+++[E5RIU6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 1 {ECO:0000313|Ensembl:ENSP00000430665}; Flags: Fragment;+++[I6L9I5_HUMAN|Unreviewed]SubName: Full=CDC2 protein {ECO:0000313|EMBL:AAI07751.1};"]
[9830,"'TRIM14'",1311,1499,2130,1646.66666666667,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0002376///immune system process+++GO:0032897///negative regulation of viral transcription+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0045087///innate immune response","tripartite motif containing 14","[TRI14_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 14;+++[A0A024R143_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_c {ECO:0000313|EMBL:EAW58876.1};+++[A0A024R165_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_a {ECO:0000313|EMBL:EAW58878.1};+++[F2Z2M2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 14 {ECO:0000313|Ensembl:ENSP00000428805};"]
[9831,"'ZNF623'",236,226,159,207,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,"R01724///5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming) Nicotinate D-ribonucleotide + Diphosphate + ADP + Orthophosphate <=> Nicotinate + 5-Phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + H+","GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 623","[ZN623_HUMAN|Reviewed]RecName: Full=Zinc finger protein 623;+++[A0A0A0MT18_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000411139};+++[A0A0J9YW98_HUMAN|Unreviewed]SubName: Full=HCG31704 {ECO:0000313|EMBL:EAW82216.1}; SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000487869};"]
[9832,"'JAKMIP2'",15,22,15.99,17.6633333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019900///kinase binding",null,"janus kinase and microtubule interacting protein 2","[JKIP2_HUMAN|Reviewed]RecName: Full=Janus kinase and microtubule-interacting protein 2; AltName: Full=CTCL tumor antigen HD-CL-04; AltName: Full=Neuroendocrine long coiled-coil protein 1;+++[Q05DV4_HUMAN|Unreviewed]SubName: Full=JAKMIP2 protein {ECO:0000313|EMBL:AAH03189.1}; Flags: Fragment;"]
[9833,"'MELK'",25,32,12,23,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005938///cell cortex+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005509///calcium ion binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0008289///lipid binding+++GO:0005524///ATP binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0030097///hemopoiesis+++GO:0016310///phosphorylation+++GO:0006915///apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0008283///cell proliferation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0007049///cell cycle+++GO:0061351///neural precursor cell proliferation","maternal embryonic leucine zipper kinase","[MELK_HUMAN|Reviewed]RecName: Full=Maternal embryonic leucine zipper kinase; Short=hMELK; EC=2.7.11.1; AltName: Full=Protein kinase Eg3; Short=pEg3 kinase; AltName: Full=Protein kinase PK38; Short=hPK38; AltName: Full=Tyrosine-protein kinase MELK; EC=2.7.10.2;+++[A0A0D9SFB9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486459};+++[A0A0D9SFF9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486558};+++[A0A0D9SFL8_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486717};+++[A0A0D9SGI4_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000487536}; Flags: Fragment;+++[B7Z1G6_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00804148}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00804148};"]
[9836,"'LCMT2'",136,187,143,155.333333333333,{"$nulls":3},"R10586///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-carboxypropyl]wyosine37-O}-methyltransferase   7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine <=> 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-homocysteine+++R10587///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methyltransferase (carbon dioxide-adding)   7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine + CO2 <=> Wybutosine in tRNA(Phe) + S-Adenosyl-L-homocysteine","GO:0005737///cytoplasm","GO:0008168///methyltransferase activity+++GO:0018423///protein C-terminal leucine carboxyl O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008175///tRNA methyltransferase activity","GO:0008033///tRNA processing+++GO:0006400///tRNA modification+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0031591///wybutosine biosynthetic process+++GO:0006481///C-terminal protein methylation","leucine carboxyl methyltransferase 2","[TYW4_HUMAN|Reviewed]RecName: Full=tRNA wybutosine-synthesizing protein 4; Short=tRNA yW-synthesizing protein 4; EC=2.1.1.290; EC=2.3.1.231; AltName: Full=Leucine carboxyl methyltransferase 2; AltName: Full=tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; AltName: Full=tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase;+++[H3BU01_HUMAN|Unreviewed]SubName: Full=tRNA wybutosine-synthesizing protein 4 {ECO:0000313|Ensembl:ENSP00000457403};"]
[9837,"'GINS1'",22,17,18,19,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00286///GINS complex",null,"GO:0005634///nucleus+++GO:0000811///GINS complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0043138///3'-5' DNA helicase activity","GO:0006271///DNA strand elongation involved in DNA replication+++GO:0001833///inner cell mass cell proliferation+++GO:1902983///DNA strand elongation involved in mitotic DNA replication+++GO:0032508///DNA duplex unwinding+++GO:0006260///DNA replication","GINS complex subunit 1","[PSF1_HUMAN|Reviewed]RecName: Full=DNA replication complex GINS protein PSF1; AltName: Full=GINS complex subunit 1;+++[L8ECJ2_HUMAN|Unreviewed]SubName: Full=Alternative protein GINS1 {ECO:0000313|EMBL:CCQ43662.1};"]
[9839,"'ZEB2'",598,670,447,571.666666666667,"05206///MicroRNAs in cancer","H00961///Posterior polymorphous corneal dystrophy (PPCD)+++H00908///Mowat-Wilson syndrome+++H00960///Fuchs corneal dystrophy (FECD)",null,null,"GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0019208///phosphatase regulator activity+++GO:0070412///R-SMAD binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0021957///corticospinal tract morphogenesis+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021766///hippocampus development+++GO:0097324///melanocyte migration+++GO:0001755///neural crest cell migration+++GO:0050772///positive regulation of axonogenesis+++GO:0021540///corpus callosum morphogenesis+++GO:0048066///developmental pigmentation+++GO:0043507///positive regulation of JUN kinase activity+++GO:1902748///positive regulation of lens fiber cell differentiation+++GO:0048668///collateral sprouting+++GO:0048598///embryonic morphogenesis+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0061373///mammillary axonal complex development+++GO:1903056///regulation of melanosome organization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021846///cell proliferation in forebrain+++GO:0007399///nervous system development+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development","zinc finger E-box binding homeobox 2","[ZEB2_HUMAN|Reviewed]RecName: Full=Zinc finger E-box-binding homeobox 2; AltName: Full=Smad-interacting protein 1; Short=SMADIP1; AltName: Full=Zinc finger homeobox protein 1b;+++[A0A0D9SF71_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486341};+++[A0A0D9SF74_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486346}; Flags: Fragment;+++[A0A0D9SG93_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487261};+++[A0A0D9SGG5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487476}; Flags: Fragment;+++[A0A1B0GTH3_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000489701}; Flags: Fragment;+++[A0A1B0GUM8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490175};+++[A0A1B0GV02_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490317};+++[A0A1B0GVV8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490673};+++[A0A1B0GW50_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490776};+++[A0A1B0GWA7_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490851};+++[A0A1B0GWI0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490934};+++[A0A1W2PS25_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000492572}; Flags: Fragment;+++[A0A1X7SC99_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490293}; Flags: Fragment;+++[A0A2R8YDQ8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000494820}; Flags: Fragment;+++[A0JP08_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|EMBL:AAI27102.1, ECO:0000313|Ensembl:ENSP00000302501};+++[C9JU62_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000400993}; Flags: Fragment;+++[C9JUQ1_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000399451}; Flags: Fragment;+++[E7ESP8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000376601}; Flags: Fragment;+++[E7EUW9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000395496}; Flags: Fragment;+++[E7EVG9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000387256}; Flags: Fragment;+++[H7C0G0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000394777};+++[Q53TD9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93276.1}; Flags: Fragment;+++[Q53TG0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93269.1}; Flags: Fragment;+++[Q60F94_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60928.1};+++[Q60F95_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60927.1};+++[Q9H4F4_HUMAN|Unreviewed]SubName: Full=Survival interacting protein 1 {ECO:0000313|EMBL:CAC16171.1}; Flags: Fragment;+++[U3KPV5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475267}; Flags: Fragment;+++[U3KPX6_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475329};+++[U3KQ33_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475502};+++[U3KQ51_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475553};"]
[984,"'CDK11B'",1021.21,1077.17,1030.78,1043.05333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016310///phosphorylation+++GO:0050684///regulation of mRNA processing+++GO:0001558///regulation of cell growth+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process","cyclin dependent kinase 11B","[CD11B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 11B; EC=2.7.11.22; AltName: Full=Cell division cycle 2-like protein kinase 1; Short=CLK-1; AltName: Full=Cell division protein kinase 11B; AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA; AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L1; AltName: Full=p58 CLK-1;+++[A0A087WYI9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000481846};+++[A0A087X1I0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000484222};+++[A0A0D9SEI3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485705};+++[A0A0D9SEN2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485849};+++[A0A0D9SER5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485937};+++[A4VCI5_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAI39778.1}; Flags: Fragment;+++[B4DII1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59025, moderately similar to PITSLRE serine/threonine-protein kinaseCDC2L1 {ECO:0000313|EMBL:BAG58493.1};+++[Q6PK02_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAH09375.1}; Flags: Fragment;"]
[9840,"'TESPA1'",3,0.98,0,1.32666666666667,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0008180///COP9 signalosome","GO:0005102///signaling receptor binding","GO:0010387///COP9 signalosome assembly+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0050862///positive regulation of T cell receptor signaling pathway","thymocyte expressed, positive selection associated 1","[TESP1_HUMAN|Reviewed]RecName: Full=Protein TESPA1; AltName: Full=Thymocyte-expressed positive selection-associated protein 1;+++[A0A024RB00_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_a {ECO:0000313|EMBL:EAW96798.1};+++[A0A024RB73_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_c {ECO:0000313|EMBL:EAW96800.1};+++[E9PHY9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436635}; Flags: Fragment;+++[E9PIN8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000435734}; Flags: Fragment;+++[E9PIT9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433895}; Flags: Fragment;+++[E9PM24_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433187}; Flags: Fragment;+++[E9PN46_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434811};+++[E9PPW8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436286}; Flags: Fragment;+++[H0YDP3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434039}; Flags: Fragment;+++[H0YEX3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436753}; Flags: Fragment;"]
[9841,"'ZBTB24'",183,186.08,164.78,177.953333333333,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 24","[ZBT24_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 24; AltName: Full=Zinc finger protein 450;"]
[9842,"'PLEKHM1'",2348,3068,2563,2659.66666666667,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0010008///endosome membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane","GO:0046872///metal ion binding","GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0035556///intracellular signal transduction+++GO:0032418///lysosome localization+++GO:0045780///positive regulation of bone resorption+++GO:1900029///positive regulation of ruffle assembly","pleckstrin homology and RUN domain containing M1","[PKHM1_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family M member 1; Short=PH domain-containing family M member 1; AltName: Full=162 kDa adapter protein; Short=AP162;+++[J3KRL8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462065}; Flags: Fragment;+++[J3KRU0_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462160};+++[J3KS30_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462282};+++[K7EII8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000464766};+++[K7EMP2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000466589}; Flags: Fragment;+++[K7EPF2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467356}; Flags: Fragment;+++[K7EQ68_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467695}; Flags: Fragment;"]
[9843,"'HEPH'",226,312,311,283,"00860///Porphyrin and chlorophyll metabolism+++04978///Mineral absorption",null,null,"R00078///Fe(II):oxygen oxidoreductase; Fe2+:oxygen   Oxygen + 4 Fe2+ + 4 H+ <=> 4 Fe3+ + 2 H2O","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005615///extracellular space","GO:0016491///oxidoreductase activity+++GO:0016722///oxidoreductase activity, oxidizing metal ions+++GO:0046872///metal ion binding+++GO:0008198///ferrous iron binding+++GO:0005507///copper ion binding+++GO:0004322///ferroxidase activity","GO:0006879///cellular iron ion homeostasis+++GO:0055114///oxidation-reduction process+++GO:0006825///copper ion transport+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0055072///iron ion homeostasis","hephaestin","[HEPH_HUMAN|Reviewed]RecName: Full=Hephaestin; EC=1.-.-.-; Flags: Precursor;+++[A0A0C4DG76_HUMAN|Unreviewed]SubName: Full=Hephaestin, isoform CRA_c {ECO:0000313|EMBL:EAX05387.1};+++[E7ES21_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000413211};+++[F8WBZ8_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000392319};+++[Q1HE23_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|EMBL:ABF47089.1};+++[Q5JZ07_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000396907}; Flags: Fragment;+++[Q5JZ08_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000398078}; Flags: Fragment;"]
[9844,"'ELMO1'",28,24,55,35.6666666666667,"05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++04062///Chemokine signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017124///SH3 domain binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0050690///regulation of defense response to virus by virus+++GO:0006909///phagocytosis+++GO:0030036///actin cytoskeleton organization+++GO:0016477///cell migration+++GO:0030029///actin filament-based process+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048870///cell motility+++GO:0006915///apoptotic process+++GO:0016601///Rac protein signal transduction+++GO:0006911///phagocytosis, engulfment","engulfment and cell motility 1","[ELMO1_HUMAN|Reviewed]RecName: Full=Engulfment and cell motility protein 1; AltName: Full=Protein ced-12 homolog;+++[A4D1X5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility 1 (Ced-12 homolog, C. elegans) {ECO:0000313|EMBL:EAL23978.1}; SubName: Full=Engulfment and cell motility 1, isoform CRA_c {ECO:0000313|EMBL:EAW94077.1}; SubName: Full=cDNA FLJ77700, highly similar to Homo sapiens engulfment and cell motility 1 (ELMO1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84473.1};+++[C9IZR8_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000406610}; Flags: Fragment;+++[C9J5X3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000397857}; Flags: Fragment;+++[C9JB20_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000391734}; Flags: Fragment;+++[C9JIW2_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000416090}; Flags: Fragment;+++[H7C0N5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000395933}; Flags: Fragment;+++[H7C0S6_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000396465}; Flags: Fragment;+++[H7C3P3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000413108}; Flags: Fragment;"]
[9846,"'GAB2'",1604,1774,1524,1634,"05220///Chronic myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++04664///Fc epsilon RI signaling pathway+++04072///Phospholipase D signaling pathway+++04071///Sphingolipid signaling pathway+++04380///Osteoclast differentiation+++04014///Ras signaling pathway","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0005515///protein binding+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity","GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043306///positive regulation of mast cell degranulation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0007411///axon guidance","GRB2 associated binding protein 2","[GAB2_HUMAN|Reviewed]RecName: Full=GRB2-associated-binding protein 2; AltName: Full=GRB2-associated binder 2; AltName: Full=Growth factor receptor bound protein 2-associated protein 2; AltName: Full=pp100;+++[E9PJ26_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000431868}; Flags: Fragment;+++[E9PJE2_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000433762}; Flags: Fragment;"]
[9847,"'C2CD5'",219,202,180,200.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0001726///ruffle+++GO:0032587///ruffle membrane+++GO:0005815///microtubule organizing center","GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005544///calcium-dependent phospholipid binding","GO:0006906///vesicle fusion+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0046326///positive regulation of glucose import+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0065002///intracellular protein transmembrane transport+++GO:0031340///positive regulation of vesicle fusion+++GO:0032869///cellular response to insulin stimulus","C2 calcium dependent domain containing 5","[C2CD5_HUMAN|Reviewed]RecName: Full=C2 domain-containing protein 5; AltName: Full=C2 domain-containing phosphoprotein of 138 kDa;+++[A0A024RB03_HUMAN|Unreviewed]SubName: Full=KIAA0528, isoform CRA_b {ECO:0000313|EMBL:EAW96475.1};+++[B7ZLK1_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43860.1};+++[B7ZLK2_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43861.1};+++[H0YFC4_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000437935}; Flags: Fragment;+++[H0YFE9_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000438256}; Flags: Fragment;+++[H0YGU7_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000444857}; Flags: Fragment;"]
[9848,"'MFAP3L'",2606,2029,1441,2025.33333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"microfibril associated protein 3 like","[MFA3L_HUMAN|Reviewed]RecName: Full=Microfibrillar-associated protein 3-like; AltName: Full=Testis development protein NYD-SP9 {ECO:0000303|Ref.1}; Flags: Precursor;+++[D6R9L7_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423549}; Flags: Fragment;+++[D6RAB5_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000422791}; Flags: Fragment;+++[D6RCC0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423802}; Flags: Fragment;+++[D6RCF0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423722}; Flags: Fragment;+++[D6RDM6_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000425303}; Flags: Fragment;+++[D6RGZ8_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000426247}; Flags: Fragment;"]
[9849,"'ZNF518A'",179,129,109,139,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04064///NF-kappa B signaling pathway+++05340///Primary immunodeficiency+++04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway","H00085///Agammaglobulinemias",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger protein 518A","[Z518A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 518A;+++[A0A087WWK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 518A {ECO:0000313|Ensembl:ENSP00000480280}; Flags: Fragment;"]
[9851,"'KIAA0753'",269,286,248,267.666666666667,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0034451///centriolar satellite+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:0007099///centriole replication+++GO:0071539///protein localization to centrosome","KIAA0753","[MOONR_HUMAN|Reviewed]RecName: Full=Protein moonraker {ECO:0000303|PubMed:26297806}; Short=MNR {ECO:0000303|PubMed:26297806}; AltName: Full=OFD1- and FOPNL-interacting protein {ECO:0000303|PubMed:26643951};+++[F6SFD5_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000444946}; Flags: Fragment;+++[I3L0P7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458247}; Flags: Fragment;+++[I3L1P2_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458983}; Flags: Fragment;+++[I3L2A7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000459530}; Flags: Fragment;+++[I3L341_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460156}; Flags: Fragment;+++[I3L3Y0_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460816};"]
[9852,"'EPM2AIP1'",573,596,579,582.666666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0032868///response to insulin+++GO:2000467///positive regulation of glycogen (starch) synthase activity+++GO:0045725///positive regulation of glycogen biosynthetic process","EPM2A interacting protein 1","[EPMIP_HUMAN|Reviewed]RecName: Full=EPM2A-interacting protein 1; AltName: Full=Laforin-interacting protein;+++[A0A096LNL1_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485091}; Flags: Fragment;+++[A0A096LPB0_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485489}; Flags: Fragment;"]
[9853,"'RUSC2'",2929,2905,2592,2808.66666666667,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0017137///Rab GTPase binding","GO:0008150///biological_process","RUN and SH3 domain containing 2","[RUSC2_HUMAN|Reviewed]RecName: Full=Iporin; AltName: Full=Interacting protein of Rab1; AltName: Full=RUN and SH3 domain-containing protein 2;"]
[9854,"'C2CD2L'",625,695,651,657,"00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome+++H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0098592///cytoplasmic side of apical plasma membrane+++GO:0016020///membrane+++GO:0032541///cortical endoplasmic reticulum","GO:0008526///phosphatidylinositol transporter activity+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0043559///insulin binding+++GO:0005548///phospholipid transporter activity","GO:0015914///phospholipid transport+++GO:0006869///lipid transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus","C2CD2 like","[C2C2L_HUMAN|Reviewed]RecName: Full=Phospholipid transfer protein C2CD2L {ECO:0000305}; AltName: Full=C2 domain-containing protein 2-like {ECO:0000312|HGNC:HGNC:29000}; Short=C2CD2-like; AltName: Full=Transmembrane protein 24 {ECO:0000303|PubMed:28209843};+++[E9PK05_HUMAN|Unreviewed]SubName: Full=Phospholipid transfer protein C2CD2L {ECO:0000313|Ensembl:ENSP00000433600};+++[Q6DHX1_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH75832.1}; Flags: Fragment;+++[Q9BTM2_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH03598.2};"]
[9855,"'FARP2'",198,210,164,190.666666666667,"04015///Rap1 signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030316///osteoclast differentiation+++GO:0033623///regulation of integrin activation+++GO:0031532///actin cytoskeleton reorganization+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0022405///hair cycle process+++GO:0016601///Rac protein signal transduction+++GO:0071800///podosome assembly+++GO:0007155///cell adhesion+++GO:0035023///regulation of Rho protein signal transduction+++GO:0016322///neuron remodeling","FERM, ARH/RhoGEF and pleckstrin domain protein 2","[FARP2_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2; AltName: Full=FERM domain-including RhoGEF; Short=FIR; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2; AltName: Full=Pleckstrin homology domain-containing family C member 3; Short=PH domain-containing family C member 3;+++[A0A2X0SSL3_HUMAN|Unreviewed]SubName: Full=FARP2 {ECO:0000313|EMBL:SPT35757.1}; Flags: Fragment;+++[C9JVQ5_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393376}; Flags: Fragment;+++[C9JWM9_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000388167}; Flags: Fragment;+++[H7C210_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000403437}; Flags: Fragment;+++[H7C3E4_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000411353}; Flags: Fragment;+++[H7C3M7_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000412772}; Flags: Fragment;+++[H7C447_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415474}; Flags: Fragment;"]
[9856,"'KIAA0319'",23,13,34,23.3333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0031901///early endosome membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0007399///nervous system development+++GO:2000171///negative regulation of dendrite development+++GO:0001764///neuron migration+++GO:0007275///multicellular organism development+++GO:0061024///membrane organization","KIAA0319","[K0319_HUMAN|Reviewed]RecName: Full=Dyslexia-associated protein KIAA0319; Flags: Precursor;+++[A0A087X0U9_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319 {ECO:0000313|Ensembl:ENSP00000483665};+++[L8E9P4_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0319 {ECO:0000313|EMBL:CCQ43461.1};"]
[9857,"'CEP350'",549,469,283,433.666666666667,{"$nulls":4},"GO:0005819///spindle+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0034453///microtubule anchoring","centrosomal protein 350","[CE350_HUMAN|Reviewed]RecName: Full=Centrosome-associated protein 350 {ECO:0000305}; Short=Cep350; AltName: Full=Centrosome-associated protein of 350 kDa {ECO:0000303|Ref.1};+++[A0A024R914_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 350kDa, isoform CRA_a {ECO:0000313|EMBL:EAW91073.1};+++[A2A4F6_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000350016}; Flags: Fragment;+++[E9PIK0_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000435808}; Flags: Fragment;+++[H0Y6Q4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000407044}; Flags: Fragment;+++[H0Y7F7_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000412460}; Flags: Fragment;+++[H0YD38_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000432910}; Flags: Fragment;+++[L8ECF2_HUMAN|Unreviewed]SubName: Full=Alternative protein CEP350 {ECO:0000313|EMBL:CCQ43462.1};+++[Q05D72_HUMAN|Unreviewed]SubName: Full=CEP350 protein {ECO:0000313|EMBL:AAH17847.1}; Flags: Fragment;+++[Q5T2X4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000401608}; Flags: Fragment;+++[Q5T2X5_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000409395}; Flags: Fragment;"]
[9858,"'PPP1R26'",352,346,251,316.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding","GO:0010923///negative regulation of phosphatase activity+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","protein phosphatase 1 regulatory subunit 26","[PPR26_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1 regulatory subunit 26;+++[A0A024R8E9_HUMAN|Unreviewed]SubName: Full=KIAA0649, isoform CRA_a {ECO:0000313|EMBL:EAW88151.1};"]
[9859,"'CEP170'",1034,1254,830,1039.33333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0120103///centriolar subdistal appendage+++GO:0005819///spindle+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule","GO:0005515///protein binding",null,"centrosomal protein 170","[CE170_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 170 kDa; Short=Cep170; AltName: Full=KARP-1-binding protein; Short=KARP1-binding protein;+++[A6H8X9_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI46791.1};+++[B2RTS4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI40795.1};+++[E5RFU8_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427944}; Flags: Fragment;+++[E5RG47_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427843}; Flags: Fragment;+++[E5RGW7_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430112}; Flags: Fragment;+++[E5RIH6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428400}; Flags: Fragment;+++[E5RJT5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428183}; Flags: Fragment;+++[E7EMW0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427842};+++[E7EWM2_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430142};+++[H0Y2V6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000338161}; Flags: Fragment;+++[H0Y4T4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000394002}; Flags: Fragment;+++[H0YB66_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428777}; Flags: Fragment;+++[H0YB92_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428996}; Flags: Fragment;+++[Q6AZE1_HUMAN|Unreviewed]SubName: Full=CEP170 protein {ECO:0000313|EMBL:AAH78155.1}; Flags: Fragment;"]
[9860,"'LRIG2'",169.08,140.01,138,149.03,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030426///growth cone+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0097708///intracellular vesicle","GO:0005102///signaling receptor binding","GO:0048681///negative regulation of axon regeneration+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0010640///regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:2001222///regulation of neuron migration+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0048679///regulation of axon regeneration+++GO:0060384///innervation+++GO:0007605///sensory perception of sound","leucine rich repeats and immunoglobulin like domains 2","[LRIG2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 2; Short=LIG-2; Flags: Precursor;"]
[9861,"'PSMD6'",581,667,658,635.333333333333,"03050///Proteasome+++05169///Epstein-Barr virus infection","H00063///Spinocerebellar ataxia (SCA)","M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0005576///extracellular region+++GO:0000502///proteasome complex+++GO:1904813///ficolin-1-rich granule lumen+++GO:0022624///proteasome accessory complex+++GO:0005829///cytosol+++GO:0005838///proteasome regulatory particle+++GO:0034774///secretory granule lumen+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0016887///ATPase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0043687///post-translational protein modification+++GO:0050790///regulation of catalytic activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043312///neutrophil degranulation","proteasome 26S subunit, non-ATPase 6","[PSMD6_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 6; AltName: Full=26S proteasome regulatory subunit RPN7; AltName: Full=26S proteasome regulatory subunit S10; AltName: Full=Breast cancer-associated protein SGA-113M; AltName: Full=Phosphonoformate immuno-associated protein 4; AltName: Full=Proteasome regulatory particle subunit p44S10; AltName: Full=p42A;+++[B3KT66_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, isoform CRA_c {ECO:0000313|EMBL:EAW65426.1}; SubName: Full=cDNA FLJ37740 fis, clone BRHIP2021870, highly similar to 26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|EMBL:BAG52978.1};+++[C9J0E9_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418887}; Flags: Fragment;+++[C9J7B7_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418303}; Flags: Fragment;+++[H7C531_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418843}; Flags: Fragment;"]
[9862,"'MED24'",1944,1868,1917,1909.66666666667,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0042809///vitamin D receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0003712///transcription coregulator activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0038023///signaling receptor activity","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0030521///androgen receptor signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated","mediator complex subunit 24","[MED24_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 24; AltName: Full=Activator-recruited cofactor 100 kDa component; Short=ARC100; AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 4; Short=CRSP complex subunit 4; AltName: Full=Mediator complex subunit 24; AltName: Full=Thyroid hormone receptor-associated protein 4; AltName: Full=Thyroid hormone receptor-associated protein complex 100 kDa component; Short=Trap100; Short=hTRAP100; AltName: Full=Vitamin D3 receptor-interacting protein complex 100 kDa component; Short=DRIP100;+++[A0A0B4J1W0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000377684}; SubName: Full=Thyroid hormone receptor associated protein 4, isoform CRA_a {ECO:0000313|EMBL:EAW60629.1};+++[B4DDR8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463751}; SubName: Full=cDNA FLJ59464, highly similar to Thyroid hormone receptor-associated proteincomplex 100 kDa component {ECO:0000313|EMBL:BAG56829.1};+++[B9TX62_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i2 {ECO:0000313|EMBL:ACB88915.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000393464}; Flags: Fragment;+++[B9TX63_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i3 {ECO:0000313|EMBL:ACB88916.1}; Flags: Fragment;+++[B9TX64_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i4 {ECO:0000313|EMBL:ACB88917.1}; Flags: Fragment;+++[B9TX65_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i5 {ECO:0000313|EMBL:ACB88918.1}; Flags: Fragment;+++[B9TX66_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i6 {ECO:0000313|EMBL:ACB88919.1}; Flags: Fragment;+++[B9TX67_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i7 {ECO:0000313|EMBL:ACB88920.1}; Flags: Fragment;+++[B9TX68_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i8 {ECO:0000313|EMBL:ACB88921.1}; Flags: Fragment;+++[B9TX69_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i9 {ECO:0000313|EMBL:ACB88922.1}; Flags: Fragment;+++[B9TX70_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i10 {ECO:0000313|EMBL:ACB88923.1}; Flags: Fragment;+++[B9TX71_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i11 {ECO:0000313|EMBL:ACB88924.1}; Flags: Fragment;+++[B9TX72_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i12 {ECO:0000313|EMBL:ACB88925.1}; Flags: Fragment;+++[B9TX73_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i13 {ECO:0000313|EMBL:ACB88926.1}; Flags: Fragment;+++[B9TX74_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i14 {ECO:0000313|EMBL:ACB88927.1}; Flags: Fragment;+++[B9TX75_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i15 {ECO:0000313|EMBL:ACB88928.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000482676};+++[B9TX76_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i16 {ECO:0000313|EMBL:ACB88929.1};+++[E9PFL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000392276}; Flags: Fragment;+++[F5GY88_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000440100};+++[F5H0M2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438767}; Flags: Fragment;+++[F5H2D6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438630}; Flags: Fragment;+++[F5H3E6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000439148};+++[F5H5K2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000443344}; Flags: Fragment;+++[H0YEG1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000435760}; Flags: Fragment;+++[J3KSL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462539}; Flags: Fragment;+++[J3KSU0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462646}; Flags: Fragment;+++[J3KTL3_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463043}; Flags: Fragment;+++[J3QLC0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463480}; Flags: Fragment;+++[J3QLC2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463484}; Flags: Fragment;+++[J3QLF8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463528}; Flags: Fragment;+++[J3QLV7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463724}; Flags: Fragment;+++[J3QRH9_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000464225}; Flags: Fragment;"]
[9863,"'MAGI2'",228,229,158,205,"04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway","H01657///Nephrotic syndrome",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005923///bicellular tight junction+++GO:0045202///synapse+++GO:0005768///endosome+++GO:0043005///neuron projection+++GO:0014069///postsynaptic density+++GO:0005770///late endosome+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030425///dendrite","GO:0030159///receptor signaling complex scaffold activity+++GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0070699///type II activin receptor binding+++GO:0070697///activin receptor binding+++GO:0016301///kinase activity+++GO:0046332///SMAD binding","GO:0007399///nervous system development+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0072015///glomerular visceral epithelial cell development+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0030336///negative regulation of cell migration+++GO:0002092///positive regulation of receptor internalization+++GO:0008285///negative regulation of cell proliferation+++GO:0043113///receptor clustering+++GO:0038180///nerve growth factor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0060395///SMAD protein signal transduction+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0071850///mitotic cell cycle arrest+++GO:0007165///signal transduction+++GO:0051291///protein heterooligomerization+++GO:0016310///phosphorylation+++GO:0003402///planar cell polarity pathway involved in axis elongation","membrane associated guanylate kinase, WW and PDZ domain containing 2","[MAGI2_HUMAN|Reviewed]RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; AltName: Full=Atrophin-1-interacting protein 1; Short=AIP-1; AltName: Full=Atrophin-1-interacting protein A; AltName: Full=Membrane-associated guanylate kinase inverted 2; Short=MAGI-2;+++[A0A0D9SET0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000485970};+++[A0A0D9SEY4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486131};+++[A0A0D9SEZ7_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486154}; Flags: Fragment;+++[A0A0D9SF86_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486379}; Flags: Fragment;+++[A0A0D9SFP3_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486774};+++[A0A0D9SFY9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487001}; Flags: Fragment;+++[A0A0D9SGF2_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487435};+++[A0A0D9SGF8_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_c {ECO:0000313|EMBL:EAW77024.1}; SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487448};+++[A0A0D9SGI1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487526};+++[A0A0E3D6M1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000441603};+++[A0A0U1RRH4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489533}; Flags: Fragment;+++[A0A1B0GTC0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489633};+++[A0A1B0GTH8_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489709}; Flags: Fragment;+++[A0A1B0GUF0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490080};+++[A0A1B0GUI9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490128}; Flags: Fragment;+++[A0A1B0GUV4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490259};+++[A0A1B0GVS0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490629}; Flags: Fragment;+++[A0A1B0GVS6_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490637};+++[B7Z4H4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61315, highly similar to Membrane-associated guanylate kinase, WW andPDZ domain-containing protein 2 {ECO:0000313|EMBL:BAH12560.1};+++[D6W5N0_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_b {ECO:0000313|EMBL:EAW77023.1};+++[E7EWI0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000428389};"]
[9865,"'TRIL'",215,41,92,116,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0046696///lipopolysaccharide receptor complex","GO:0001530///lipopolysaccharide binding","GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response+++GO:0002718///regulation of cytokine production involved in immune response","TLR4 interactor with leucine rich repeats","[TRIL_HUMAN|Reviewed]RecName: Full=TLR4 interactor with leucine rich repeats; AltName: Full=Leucine-rich repeat-containing protein KIAA0644; Flags: Precursor;"]
[9866,"'TRIM66'",245,300,218,254.333333333333,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016235///aggresome","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0045892///negative regulation of transcription, DNA-templated","tripartite motif containing 66","[TRI66_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 66;+++[A0A2R8YE93_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000494157}; Flags: Fragment;+++[A0A2R8YEA1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000495413};+++[B5MCJ9_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000384876};+++[H0YF52_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000437234}; Flags: Fragment;"]
[9867,"'PJA2'",1794,1547,1206,1515.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045202///synapse+++GO:0005783///endoplasmic reticulum+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0045111///intermediate filament cytoskeleton+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm","GO:0034236///protein kinase A catalytic subunit binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity","GO:0006954///inflammatory response+++GO:0035329///hippo signaling+++GO:0016567///protein ubiquitination+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0045087///innate immune response+++GO:0043030///regulation of macrophage activation+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0010738///regulation of protein kinase A signaling+++GO:0007616///long-term memory","praja ring finger ubiquitin ligase 2","[PJA2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Praja-2; Short=Praja2; EC=2.3.2.27; AltName: Full=RING finger protein 131; AltName: Full=RING-type E3 ubiquitin transferase Praja-2 {ECO:0000305};"]
[9868,"'TOMM70'",810,701,675,728.666666666667,{"$nulls":4},"GO:0005742///mitochondrial outer membrane translocase complex+++GO:0070062///extracellular exosome+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding","GO:0071806///protein transmembrane transport+++GO:0006626///protein targeting to mitochondrion","translocase of outer mitochondrial membrane 70","[TOM70_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM70; AltName: Full=Mitochondrial precursor proteins import receptor; AltName: Full=Translocase of outer membrane 70 kDa subunit; AltName: Full=Translocase of outer mitochondrial membrane protein 70 {ECO:0000312|HGNC:HGNC:11985};"]
[9869,"'SETDB1'",486,486,434,468.666666666667,"04550///Signaling pathways regulating pluripotency of stem cells+++00310///Lysine degradation",null,null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm","GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:1990841///promoter-specific chromatin binding+++GO:0016740///transferase activity","GO:0045471///response to ethanol+++GO:0032259///methylation+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0006325///chromatin organization+++GO:0033273///response to vitamin+++GO:0007265///Ras protein signal transduction+++GO:0034968///histone lysine methylation","SET domain bifurcated 1","[SETB1_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETDB1; EC=2.1.1.43; AltName: Full=ERG-associated protein with SET domain; Short=ESET; AltName: Full=Histone H3-K9 methyltransferase 4; Short=H3-K9-HMTase 4; AltName: Full=Lysine N-methyltransferase 1E; AltName: Full=SET domain bifurcated 1;+++[B0QZE6_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000409379}; Flags: Fragment;+++[E9PAP1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357960};+++[E9PQM8_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000436148}; Flags: Fragment;+++[E9PRF4_HUMAN|Unreviewed]RecName: Full=Histone-lysine N-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00906}; EC=2.1.1.43 {ECO:0000256|PROSITE-ProRule:PRU00906}; Flags: Fragment;+++[E9PS59_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000435922}; Flags: Fragment;+++[X6R732_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357959};+++[X6RHV1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000407831}; Flags: Fragment;"]
[987,"'LRBA'",1182,971,793,982,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0008150///biological_process","LPS responsive beige-like anchor protein","[LRBA_HUMAN|Reviewed]RecName: Full=Lipopolysaccharide-responsive and beige-like anchor protein; AltName: Full=Beige-like protein; AltName: Full=CDC4-like protein;+++[E9PEM5_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000422180};+++[H0Y9N9_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000424640}; Flags: Fragment;+++[H0YA17_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000425852}; Flags: Fragment;+++[H0YAC6_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000426669}; Flags: Fragment;+++[Q6P1X2_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH64834.1};+++[Q969R7_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH12535.2}; Flags: Fragment;"]
[9870,"'AREL1'",1257,1315,951,1174.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0006915///apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process","apoptosis resistant E3 ubiquitin protein ligase 1","[AREL1_HUMAN|Reviewed]RecName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1; EC=2.3.2.26; AltName: Full=Apoptosis-resistant HECT-type E3 ubiquitin transferase 1;+++[G3V245_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450458}; Flags: Fragment;+++[G3V2B5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450557};+++[G3V506_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452101}; Flags: Fragment;+++[G3V5P7_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452456};+++[H0YJ67_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450901}; Flags: Fragment;+++[H0YJ69_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450912}; Flags: Fragment;+++[H0YJF1_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451375}; Flags: Fragment;+++[H0YJK5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451710}; Flags: Fragment;+++[L8E7E7_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0317 {ECO:0000313|EMBL:CCQ43054.1};"]
[9871,"'SEC24D'",940,1065,727,910.666666666667,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0030127///COPII vesicle coat+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum","GO:0000149///SNARE binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0090110///cargo loading into COPII-coated vesicle+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0016192///vesicle-mediated transport+++GO:0001701///in utero embryonic development+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I","SEC24 homolog D, COPII coat complex component","[SC24D_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24D {ECO:0000305}; AltName: Full=SEC24-related protein D;+++[A8K6V0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78676, highly similar to Homo sapiens SEC24 related gene family, member D (SEC24D), mRNA {ECO:0000313|EMBL:BAF84454.1};+++[D6RAE2_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000422717};+++[D6RBM1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000424085};+++[D6RGJ5_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000426309}; Flags: Fragment;+++[E9PC44_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43974 fis, clone TESTI4018101, highly similar to Protein transport protein Sec24D {ECO:0000313|EMBL:BAG54271.1};+++[E9PDM8_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000425491};+++[E9PG84_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000427249};+++[Q49AI3_HUMAN|Unreviewed]SubName: Full=SEC24D protein {ECO:0000313|EMBL:AAH37736.1};+++[Q4W5D3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEC24D {ECO:0000313|EMBL:AAY40935.1}; Flags: Fragment;"]
[9873,"'FCHSD2'",330,280,242,284,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0055037///recycling endosome","GO:0005515///protein binding","GO:0007274///neuromuscular synaptic transmission+++GO:0030833///regulation of actin filament polymerization","FCH and double SH3 domains 2","[FCSD2_HUMAN|Reviewed]RecName: Full=F-BAR and double SH3 domains protein 2; AltName: Full=Carom; AltName: Full=SH3 multiple domains protein 3;+++[A0A024R5H2_HUMAN|Unreviewed]SubName: Full=FCH and double SH3 domains 2, isoform CRA_a {ECO:0000313|EMBL:EAW74881.1};+++[B8ZZW8_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386903};+++[C9JM66_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000408706}; Flags: Fragment;+++[E7ENZ2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000402972};+++[E9PG19_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386987};+++[H0Y6M2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000406420}; Flags: Fragment;+++[H0YG35_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000441616}; Flags: Fragment;"]
[9874,"'TLK1'",862,815,668,781.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006325///chromatin organization+++GO:0001672///regulation of chromatin assembly or disassembly+++GO:0007049///cell cycle+++GO:0006886///intracellular protein transport","tousled like kinase 1","[TLK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase tousled-like 1; EC=2.7.11.1; AltName: Full=PKU-beta; AltName: Full=Tousled-like kinase 1;+++[B3KRP1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000387313}; SubName: Full=Tousled-like kinase 1, isoform CRA_b {ECO:0000313|EMBL:EAX11221.1}; SubName: Full=cDNA FLJ34656 fis, clone KIDNE2018352, highly similar to Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|EMBL:BAG52453.1};+++[C9JWT6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000393165}; Flags: Fragment;+++[F8W7X8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000352810};+++[Q53TE4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAY15077.1}; Flags: Fragment;+++[Q53TF9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAX93162.1}; Flags: Fragment;"]
[9875,"'URB1'",1035,1002,822,953,{"$nulls":4},"GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0008150///biological_process+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","URB1 ribosome biogenesis homolog","[NPA1P_HUMAN|Reviewed]RecName: Full=Nucleolar pre-ribosomal-associated protein 1; AltName: Full=Nucleolar protein 254 kDa; AltName: Full=URB1 ribosome biogenesis 1 homolog;"]
[9877,"'ZC3H11A'",1784.37,1841,1613.78,1746.38333333333,{"$nulls":4},"GO:0000346///transcription export complex+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003729///mRNA binding","GO:0006405///RNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031124///mRNA 3'-end processing+++GO:0051028///mRNA transport","zinc finger CCCH-type containing 11A","[ZC11A_HUMAN|Reviewed]RecName: Full=Zinc finger CCCH domain-containing protein 11A;+++[A0A1W2PPR9_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000491483};+++[C9J0L0_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000406531}; Flags: Fragment;+++[E9PBY7_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000415072}; Flags: Fragment;+++[E9PQ61_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000432602};+++[Q0D2N5_HUMAN|Unreviewed]SubName: Full=ZC3H11A protein {ECO:0000313|EMBL:AAH46137.1};"]
[9878,"'TOX4'",1331,1556,1402,1429.66666666667,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0030175///filopodium+++GO:0031225///anchored component of membrane+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0005576///extracellular region+++GO:0042995///cell projection+++GO:0032432///actin filament bundle+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0042627///chylomicron+++GO:0001891///phagocytic cup+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0032587///ruffle membrane+++GO:0002102///podosome+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0015629///actin cytoskeleton+++GO:0000785///chromatin+++GO:0034361///very-low-density lipoprotein particle+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0001726///ruffle","GO:0008201///heparin binding+++GO:0004806///triglyceride lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003779///actin binding+++GO:0051020///GTPase binding+++GO:0004465///lipoprotein lipase activity+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0034185///apolipoprotein binding+++GO:0051015///actin filament binding+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0004620///phospholipase activity+++GO:0017129///triglyceride binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding","GO:0051639///actin filament network formation+++GO:0050729///positive regulation of inflammatory response+++GO:0022617///extracellular matrix disassembly+++GO:0019433///triglyceride catabolic process+++GO:0031100///animal organ regeneration+++GO:0006641///triglyceride metabolic process+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0044319///wound healing, spreading of cells+++GO:0006644///phospholipid metabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0070328///triglyceride homeostasis+++GO:0016477///cell migration+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0002286///T cell activation involved in immune response+++GO:0009409///response to cold+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0010737///protein kinase A signaling+++GO:0071803///positive regulation of podosome assembly+++GO:0034371///chylomicron remodeling+++GO:0006633///fatty acid biosynthetic process+++GO:0033157///regulation of intracellular protein transport+++GO:0016042///lipid catabolic process+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0090197///positive regulation of chemokine secretion+++GO:0042632///cholesterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0009617///response to bacterium+++GO:0042493///response to drug+++GO:0009749///response to glucose+++GO:0010886///positive regulation of cholesterol storage+++GO:0051017///actin filament bundle assembly+++GO:0006357///regulation of transcription by RNA polymerase II","TOX high mobility group box family member 4","[TOX4_HUMAN|Reviewed]RecName: Full=TOX high mobility group box family member 4; AltName: Full=Epidermal Langerhans cell protein LCP1;+++[C9J919_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000406196}; Flags: Fragment;+++[C9JNL1_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000402195}; Flags: Fragment;+++[F8WBE8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000389333};+++[F8WC04_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392234};+++[F8WCL8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392482};+++[Q5TBN3_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000408052}; Flags: Fragment;+++[Q5TBN5_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000402157}; Flags: Fragment;"]
[9879,"'DDX46'",737,732,700,723,"03040///Spliceosome",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","DEAD-box helicase 46","[DDX46_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX46; EC=3.6.4.13; AltName: Full=DEAD box protein 46; AltName: Full=PRP5 homolog;+++[A0A0C4DG89_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000416534};+++[D3DQA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_a {ECO:0000313|EMBL:EAW62242.1};+++[D6RJA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_b {ECO:0000313|EMBL:EAW62239.1}; SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000427290};+++[H0Y9U3_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000425073}; Flags: Fragment;+++[H0YAD5_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000426767}; Flags: Fragment;+++[Q0VGL8_HUMAN|Unreviewed]SubName: Full=DDX46 protein {ECO:0000313|EMBL:AAI05599.1}; Flags: Fragment;"]
[988,"'CDC5L'",695,643,574.99,637.663333333333,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0016020///membrane+++GO:0000974///Prp19 complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005662///DNA replication factor A complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0016607///nuclear speck+++GO:0032993///protein-DNA complex+++GO:0071013///catalytic step 2 spliceosome","GO:0001222///transcription corepressor binding+++GO:0008157///protein phosphatase 1 binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0043522///leucine zipper domain binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0071987///WD40-repeat domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0000278///mitotic cell cycle+++GO:0000398///mRNA splicing, via spliceosome+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0008380///RNA splicing+++GO:0006974///cellular response to DNA damage stimulus+++GO:1904568///cellular response to wortmannin+++GO:0072422///signal transduction involved in DNA damage checkpoint+++GO:0007049///cell cycle+++GO:0071352///cellular response to interleukin-2+++GO:1990646///cellular response to prolactin+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006397///mRNA processing","cell division cycle 5 like","[CDC5L_HUMAN|Reviewed]RecName: Full=Cell division cycle 5-like protein; Short=Cdc5-like protein; AltName: Full=Pombe cdc5-related protein;"]
[9880,"'ZBTB39'",127,151,140,139.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 39","[ZBT39_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 39;"]
[9881,"'TRANK1'",240,238,217,231.666666666667,{"$nulls":5},"GO:0005524///ATP binding",null,"tetratricopeptide repeat and ankyrin repeat containing 1","[TRNK1_HUMAN|Reviewed]RecName: Full=TPR and ankyrin repeat-containing protein 1; AltName: Full=Lupus brain antigen 1 homolog;+++[A0A096LPF5_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000485569}; Flags: Fragment;+++[A0A2R8Y7N6_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496256}; Flags: Fragment;+++[A0A2R8Y890_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496740}; Flags: Fragment;+++[A0A2R8Y8A3_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496771};+++[A0A2R8YEM9_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000494480};+++[L8EAQ6_HUMAN|Unreviewed]SubName: Full=Alternative protein TRANK1 {ECO:0000313|EMBL:CCQ43463.1};"]
[9882,"'TBC1D4'",76,60,43,59.6666666666667,"04931///Insulin resistance+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031982///vesicle+++GO:0005829///cytosol","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0016192///vesicle-mediated transport+++GO:0032869///cellular response to insulin stimulus+++GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport+++GO:0031339///negative regulation of vesicle fusion+++GO:0043547///positive regulation of GTPase activity","TBC1 domain family member 4","[TBCD4_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 4; AltName: Full=Akt substrate of 160 kDa; Short=AS160;+++[A0A024R637_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW80538.1};+++[Q5JU47_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 4 {ECO:0000313|Ensembl:ENSP00000396932}; Flags: Fragment;"]
[9883,"'POM121'",3792.63,3706.33,3048.85,3515.93666666667,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0032389///MutLalpha complex","GO:0008139///nuclear localization sequence binding+++GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0017056///structural constituent of nuclear pore+++GO:0046872///metal ion binding","GO:0006606///protein import into nucleus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0016032///viral process+++GO:0006310///DNA recombination+++GO:0006298///mismatch repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus","POM121 transmembrane nucleoporin","[P121A_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;"]
[9884,"'LRRC37A'",102.53,113.83,76.68,97.68,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0030496///midbody","GO:0044877///protein-containing complex binding+++GO:0016887///ATPase activity+++GO:0017075///syntaxin-1 binding+++GO:0042623///ATPase activity, coupled+++GO:0000149///SNARE binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding","GO:0006813///potassium ion transport+++GO:0035494///SNARE complex disassembly+++GO:0015031///protein transport","leucine rich repeat containing 37A","[L37A1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 37A; Flags: Precursor;"]
[9885,"'OSBPL2'",707.9,676.04,623,668.98,"05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04151///PI3K-Akt signaling pathway+++01100///Metabolic pathways+++05200///Pathways in cancer+++05146///Amoebiasis+++05145///Toxoplasmosis+++05165///Human papillomavirus infection+++04510///Focal adhesion","H00586///Epidermolysis bullosa, junctional+++H00813///Laryngo onycho cutaneous syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0015248///sterol transporter activity+++GO:0005515///protein binding+++GO:0032934///sterol binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding","GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0006699///bile acid biosynthetic process","oxysterol binding protein like 2","[OSBL2_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 2; Short=ORP-2; Short=OSBP-related protein 2;+++[A0A087WTV1_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000478158}; Flags: Fragment;+++[A0A087WVV0_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000479702}; Flags: Fragment;+++[A0A2R8Y362_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;+++[A0A2R8Y429_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000493721};+++[A0A2R8Y5B9_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000494692};+++[A0A2R8Y5R1_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y690_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y703_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495611};+++[A0A2R8YD49_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YDU7_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YEX0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YFT0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG53_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495661}; Flags: Fragment;+++[A0A2R8YG59_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG95_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[B4DKJ8_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[E7ET92_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[H0Y7X4_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;"]
[9886,"'RHOBTB1'",403,484,326,404.333333333333,"04120///Ubiquitin mediated proteolysis","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding","GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0043652///engulfment of apoptotic cell+++GO:0016477///cell migration+++GO:0007264///small GTPase mediated signal transduction+++GO:0000902///cell morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho related BTB domain containing 1","[RHBT1_HUMAN|Reviewed]RecName: Full=Rho-related BTB domain-containing protein 1;+++[A0A024QZL4_HUMAN|Unreviewed]SubName: Full=Rho-related BTB domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW54216.1};+++[Q567T3_HUMAN|Unreviewed]SubName: Full=RHOBTB1 protein {ECO:0000313|EMBL:AAH93035.1};"]
[9887,"'SMG7'",1663,1652,1325,1546.66666666667,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton","GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0004540///ribonuclease activity+++GO:0070034///telomerase RNA binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0051721///protein phosphatase 2A binding","GO:0007004///telomere maintenance via telomerase+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0035303///regulation of dephosphorylation+++GO:0043487///regulation of RNA stability+++GO:0006406///mRNA export from nucleus","SMG7, nonsense mediated mRNA decay factor","[SMG7_HUMAN|Reviewed]RecName: Full=Protein SMG7; AltName: Full=EST1-like protein C; AltName: Full=SMG-7 homolog; Short=hSMG-7;+++[B1ALB4_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000388390}; Flags: Fragment;+++[D6R9J3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422056}; Flags: Fragment;+++[D6RAD0_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422742}; Flags: Fragment;+++[E9PBK2_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000400220};+++[E9PD50_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000356507};+++[E9PEK3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000410254};+++[Q6TV06_HUMAN|Unreviewed]SubName: Full=Breast cancer-associated antigen SGA-56M {ECO:0000313|EMBL:AAR25620.1}; SubName: Full=Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), isoform CRA_a {ECO:0000313|EMBL:EAW91154.1};"]
[9889,"'ZBED4'",581,642,494,572.333333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","zinc finger BED-type containing 4","[ZBED4_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 4;"]
[989,"'SEPT7'",1093,1125,1018,1078.66666666667,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016324///apical plasma membrane+++GO:0000775///chromosome, centromeric region+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0031105///septin complex+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0097730///non-motile cilium+++GO:0005634///nucleus+++GO:0031514///motile cilium+++GO:0005930///axoneme+++GO:0032160///septin filament array+++GO:0097227///sperm annulus+++GO:0032154///cleavage furrow+++GO:0001725///stress fiber+++GO:0005929///cilium+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0005198///structural molecule activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding","GO:0051301///cell division+++GO:0016476///regulation of embryonic cell shape+++GO:0000281///mitotic cytokinesis+++GO:0051291///protein heterooligomerization+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0060271///cilium assembly+++GO:0030154///cell differentiation+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:0000921///septin ring assembly","septin 7","[SEPT7_HUMAN|Reviewed]RecName: Full=Septin-7; AltName: Full=CDC10 protein homolog;+++[A0A023T695_HUMAN|Unreviewed]SubName: Full=Septin 7 variant 4 {ECO:0000313|EMBL:AHX84171.1};+++[A0A024RA87_HUMAN|Unreviewed]SubName: Full=Septin 7, isoform CRA_a {ECO:0000313|EMBL:EAW94060.1};+++[A0A0U1RQW0_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489192}; Flags: Fragment;+++[A0A0U1RRD1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489466}; Flags: Fragment;+++[A0A0U1RRE1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489480}; Flags: Fragment;+++[A0A0U1RRH9_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489538}; Flags: Fragment;+++[A0A0U1RRM2_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489596}; Flags: Fragment;+++[A8K3D0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75185 {ECO:0000313|EMBL:BAF83234.1};+++[B4DNE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52574, highly similar to Septin-7 {ECO:0000313|EMBL:BAG60206.1};+++[E7EPK1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000344868};+++[E7ES33_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000381993};+++[G3V1Q4_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000413507};+++[Q3B7A3_HUMAN|Unreviewed]SubName: Full=SEPT7 protein {ECO:0000313|EMBL:AAI07719.1}; Flags: Fragment;+++[Q5JXL7_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000444240};+++[Q8TC62_HUMAN|Unreviewed]SubName: Full=Septin 7 {ECO:0000313|EMBL:AAH25987.3};"]
[9890,"'PLPPR4'",1,5,0,2,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099061///integral component of postsynaptic density membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0016791///phosphatase activity+++GO:0016787///hydrolase activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0042577///lipid phosphatase activity","GO:0007409///axonogenesis+++GO:0046839///phospholipid dephosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0048839///inner ear development+++GO:0006644///phospholipid metabolic process","phospholipid phosphatase related 4","[PLPR4_HUMAN|Reviewed]RecName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000305}; EC=3.1.3.4; AltName: Full=Brain-specific phosphatidic acid phosphatase-like protein 1 {ECO:0000303|Ref.7}; AltName: Full=Lipid phosphate phosphatase-related protein type 4 {ECO:0000303|Ref.2}; AltName: Full=Plasticity-related gene 1 protein {ECO:0000305|PubMed:12730698}; Short=PRG-1 {ECO:0000303|PubMed:12730698};+++[Q3ZCT6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH41386.1}; Flags: Fragment;+++[Q86XM6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH42963.1}; Flags: Fragment;+++[W4VSQ3_HUMAN|Unreviewed]SubName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000313|Ensembl:ENSP00000359203};"]
[9891,"'NUAK1'",615,808,616,679.666666666667,{"$nulls":4},"GO:0001650///fibrillar center+++GO:0015630///microtubule cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0002039///p53 binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0042127///regulation of cell proliferation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0007155///cell adhesion+++GO:0030155///regulation of cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035507///regulation of myosin-light-chain-phosphatase activity+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000772///regulation of cellular senescence","NUAK family kinase 1","[NUAK1_HUMAN|Reviewed]RecName: Full=NUAK family SNF1-like kinase 1; EC=2.7.11.1; AltName: Full=AMPK-related protein kinase 5; Short=ARK5; AltName: Full=Omphalocele kinase 1;+++[A0A024RBL3_HUMAN|Unreviewed]SubName: Full=NUAK family, SNF1-like kinase, 1, isoform CRA_a {ECO:0000313|EMBL:EAW97769.1};+++[F8VSH4_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000448288}; Flags: Fragment;+++[F8VXF0_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000449990}; Flags: Fragment;+++[F8VZ96_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000446873}; Flags: Fragment;"]
[9892,"'SNAP91'",123,84,76,94.3333333333333,{"$nulls":4},"GO:0030136///clathrin-coated vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005905///clathrin-coated pit","GO:0030276///clathrin binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0019901///protein kinase binding","GO:0048268///clathrin coat assembly+++GO:0015031///protein transport+++GO:2000369///regulation of clathrin-dependent endocytosis","synaptosome associated protein 91","[AP180_HUMAN|Reviewed]RecName: Full=Clathrin coat assembly protein AP180; AltName: Full=91 kDa synaptosomal-associated protein; AltName: Full=Clathrin coat-associated protein AP180; AltName: Full=Phosphoprotein F1-20;+++[A0A0A0MRM7_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358705}; Flags: Fragment;+++[B7Z2N2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57108, highly similar to Clathrin coat assembly protein AP180 {ECO:0000313|EMBL:BAH11918.1};+++[E5RFC6_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358704}; Flags: Fragment;+++[E5RFU0_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000427959}; Flags: Fragment;+++[E5RGP8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429950};+++[E5RGY9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430071}; Flags: Fragment;+++[E5RHK9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429700};+++[E5RIJ5_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429429}; Flags: Fragment;+++[E5RJY3_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000431055}; Flags: Fragment;+++[E5RK51_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430441}; Flags: Fragment;+++[E5RK53_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000428127};+++[E9PDG8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429776};+++[H0UI15_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein, 91kDa homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW48659.1};+++[H0YBT2_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430255}; Flags: Fragment;"]
[9894,"'TELO2'",551,504,517,524,"04150///mTOR signaling pathway+++03460///Fanconi anemia pathway","H01789///You-Hoover-Fong syndrome",null,null,"GO:0000784///nuclear chromosome, telomeric region+++GO:0034399///nuclear periphery+++GO:0005622///intracellular+++GO:0031932///TORC2 complex+++GO:0016607///nuclear speck+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0031931///TORC1 complex+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0070209///ASTRA complex","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004713///protein tyrosine kinase activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0042162///telomeric DNA binding+++GO:0051879///Hsp90 protein binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:1904263///positive regulation of TORC1 signaling+++GO:0000723///telomere maintenance+++GO:0032526///response to retinoic acid+++GO:1904515///positive regulation of TORC2 signaling+++GO:0006468///protein phosphorylation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0032006///regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation+++GO:0010033///response to organic substance+++GO:0010212///response to ionizing radiation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0071902///positive regulation of protein serine/threonine kinase activity","telomere maintenance 2","[TELO2_HUMAN|Reviewed]RecName: Full=Telomere length regulation protein TEL2 homolog; AltName: Full=Protein clk-2 homolog; Short=hCLK2;+++[B4DXS2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58340 {ECO:0000313|EMBL:BAG63484.1};+++[H3BRS3_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000456383};+++[H3BU45_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000457461}; Flags: Fragment;+++[Q9BRG8_HUMAN|Unreviewed]SubName: Full=CLK2 protein {ECO:0000313|EMBL:AAH06274.2}; Flags: Fragment;"]
[9895,"'TECPR2'",1894,1602,1513,1669.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005515///protein binding","GO:0006914///autophagy","tectonin beta-propeller repeat containing 2","[TCPR2_HUMAN|Reviewed]RecName: Full=Tectonin beta-propeller repeat-containing protein 2; AltName: Full=WD repeat-containing protein KIAA0329/KIAA0297;+++[L8E8K7_HUMAN|Unreviewed]SubName: Full=Alternative protein TECPR2 {ECO:0000313|EMBL:CCQ43464.1};"]
[9896,"'FIG4'",385,403,362,383.333333333333,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase ATP + dCDP <=> ADP + dCTP+++R00156///ATP:UDP phosphotransferase ATP + UDP <=> ADP + UTP+++R00722///ATP:IDP phosphotransferase ATP + IDP <=> ADP + ITP+++R02093///ATP:dTDP phosphotransferase ATP + dTDP <=> ADP + dTTP+++R01547///ATP:dAMP phosphotransferase ATP + dAMP <=> ADP + dADP+++R00330///ATP:GDP phosphotransferase ATP + GDP <=> ADP + GTP+++R00570///ATP:CDP phosphotransferase ATP + CDP <=> ADP + CTP+++R00124///ATP:ADP phosphatransferase ATP + ADP <=> ADP + ATP+++R03530///ATP:dIDP phosphotransferase ATP + dIDP <=> ADP + dITP+++R00127///ATP:AMP phosphotransferase ATP + AMP <=> 2 ADP+++R01857///ATP:dGDP phosphotransferase ATP + dGDP <=> ADP + dGTP+++R02331///ATP:dUDP phosphotransferase ATP + dUDP <=> ADP + dUTP+++R01137///ATP:dADP phosphotransferase ATP + dADP <=> ADP + dATP","GO:0043231///intracellular membrane-bounded organelle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0010008///endosome membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005811///lipid droplet+++GO:0055037///recycling endosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0042578///phosphoric ester hydrolase activity+++GO:0034593///phosphatidylinositol bisphosphate phosphatase activity+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0043813///phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity","GO:0046488///phosphatidylinositol metabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0007626///locomotory behavior+++GO:0032288///myelin assembly+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0048666///neuron development+++GO:0016311///dephosphorylation+++GO:0031642///negative regulation of myelination+++GO:0007033///vacuole organization+++GO:0043473///pigmentation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process","FIG4 phosphoinositide 5-phosphatase","[FIG4_HUMAN|Reviewed]RecName: Full=Polyphosphoinositide phosphatase; EC=3.1.3.-; AltName: Full=Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; AltName: Full=SAC domain-containing protein 3;+++[H0Y6G7_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000405660}; Flags: Fragment;+++[Q5JRV4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000396566}; Flags: Fragment;+++[Q5TCS4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000357937};+++[Q5TCS5_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000412156}; Flags: Fragment;"]
[9897,"'WASHC5'",1182,1170,931,1094.33333333333,"04144///Endocytosis","H00266///Hereditary spastic paraplegia (SPG)+++H01568///3C syndrome",null,null,"GO:0005768///endosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005769///early endosome+++GO:0071203///WASH complex+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0001556///oocyte maturation+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0010976///positive regulation of neuron projection development+++GO:0090306///spindle assembly involved in meiosis+++GO:0015031///protein transport+++GO:0016197///endosomal transport","WASH complex subunit 5","[WASC5_HUMAN|Reviewed]RecName: Full=WASH complex subunit 5 {ECO:0000312|HGNC:HGNC:28984}; AltName: Full=Strumpellin; AltName: Full=WASH complex subunit strumpellin {ECO:0000305};+++[E5RFU6_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000427946}; Flags: Fragment;+++[E7EQI7_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000429676};"]
[9898,"'UBAP2L'",5911,6169,5989,6023,null,"H00100///Neutropenic disorders",null,null,"GO:0031519///PcG protein complex+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0007339///binding of sperm to zona pellucida+++GO:0061484///hematopoietic stem cell homeostasis","ubiquitin associated protein 2 like","[UBP2L_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated protein 2-like; AltName: Full=Protein NICE-4;+++[B4DYY5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55671, highly similar to Ubiquitin-associated protein 2-like {ECO:0000313|EMBL:BAG63897.1};+++[F8W726_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000271877};+++[H0Y5H6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000398609}; Flags: Fragment;+++[H7C2T8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000407672}; Flags: Fragment;+++[Q5VU77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000357490}; Flags: Fragment;+++[Q5VU78_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389052}; Flags: Fragment;+++[Q5VU79_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389717}; Flags: Fragment;+++[Q5VU80_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000415310}; Flags: Fragment;+++[Q5VU81_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000399920}; Flags: Fragment;"]
[9899,"'SV2B'",50.94,13.97,22.96,29.29,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0030672///synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction","GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0022857///transmembrane transporter activity","GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport+++GO:0006836///neurotransmitter transport","synaptic vesicle glycoprotein 2B","[SV2B_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2B;"]
[990,"'CDC6'",37,79,49,55,"04110///Cell cycle+++04111///Cell cycle - yeast+++04113///Meiosis - yeast","H01889///Meier-Gorlin syndrome",null,null,"GO:0005634///nucleus+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0051233///spindle midzone+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006270///DNA replication initiation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0051984///positive regulation of chromosome segregation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1904385///cellular response to angiotensin+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0032467///positive regulation of cytokinesis+++GO:0033314///mitotic DNA replication checkpoint+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0007089///traversing start control point of mitotic cell cycle+++GO:0000076///DNA replication checkpoint+++GO:1904117///cellular response to vasopressin+++GO:0006260///DNA replication+++GO:0051301///cell division+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000278///mitotic cell cycle","cell division cycle 6","[CDC6_HUMAN|Reviewed]RecName: Full=Cell division control protein 6 homolog; AltName: Full=CDC6-related protein; AltName: Full=Cdc18-related protein; Short=HsCdc18; AltName: Full=p62(cdc6); Short=HsCDC6;+++[A0A024R1S2_HUMAN|Unreviewed]RecName: Full=Cell division control protein {ECO:0000256|PIRNR:PIRNR001767};+++[J3KTI7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463004}; Flags: Fragment;+++[J3QLN7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463635}; Flags: Fragment;+++[J3QR52_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000464047}; Flags: Fragment;"]
[9900,"'SV2A'",316,348,313,325.666666666667,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0048786///presynaptic active zone+++GO:0045202///synapse+++GO:0098982///GABA-ergic synapse+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0098978///glutamatergic synapse+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030672///synaptic vesicle membrane+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0043005///neuron projection+++GO:0030425///dendrite","GO:0005215///transporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0014052///regulation of gamma-aminobutyric acid secretion+++GO:0006874///cellular calcium ion homeostasis+++GO:0006836///neurotransmitter transport+++GO:0007268///chemical synaptic transmission+++GO:0016082///synaptic vesicle priming","synaptic vesicle glycoprotein 2A","[SV2A_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2A;+++[B4E000_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57689, highly similar to Synaptic vesicle glycoprotein 2A {ECO:0000313|EMBL:BAG64262.1};+++[L8E840_HUMAN|Unreviewed]SubName: Full=Alternative protein SV2A {ECO:0000313|EMBL:CCQ43465.1};"]
[9901,"'SRGAP3'",327,308,262,299,"04360///Axon guidance",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005730///nucleolus","GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0016423///tRNA (guanine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0032197///transposition, RNA-mediated+++GO:0030488///tRNA methylation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","SLIT-ROBO Rho GTPase activating protein 3","[SRGP3_HUMAN|Reviewed]RecName: Full=SLIT-ROBO Rho GTPase-activating protein 3; Short=srGAP3; AltName: Full=Mental disorder-associated GAP; AltName: Full=Rho GTPase-activating protein 14; AltName: Full=WAVE-associated Rac GTPase-activating protein; Short=WRP;"]
[9902,"'MRC2'",3005,3505,3036,3182,"04145///Phagosome+++05152///Tuberculosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005518///collagen binding","GO:0030574///collagen catabolic process+++GO:0001649///osteoblast differentiation+++GO:0006897///endocytosis","mannose receptor C type 2","[MRC2_HUMAN|Reviewed]RecName: Full=C-type mannose receptor 2; AltName: Full=C-type lectin domain family 13 member E; AltName: Full=Endocytic receptor 180; AltName: Full=Macrophage mannose receptor 2; AltName: Full=Urokinase-type plasminogen activator receptor-associated protein; Short=UPAR-associated protein; Short=Urokinase receptor-associated protein; AltName: CD_antigen=CD280; Flags: Precursor;+++[E7EME3_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000400445};+++[J3KRF1_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000461968}; Flags: Fragment;+++[J3QQZ6_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000463968}; Flags: Fragment;"]
[9903,"'KLHL21'",2091,1990,2042,2041,{"$nulls":4},"GO:0005819///spindle+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005827///polar microtubule","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0035853///chromosome passenger complex localization to spindle midzone+++GO:0032465///regulation of cytokinesis+++GO:0016567///protein ubiquitination","kelch like family member 21","[KLH21_HUMAN|Reviewed]RecName: Full=Kelch-like protein 21;+++[K7ELI0_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466089};+++[K7EMF2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466479};+++[K7ESH2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000468710}; Flags: Fragment;+++[L8E9P8_HUMAN|Unreviewed]SubName: Full=Alternative protein KLHL21 {ECO:0000313|EMBL:CCQ43466.1};+++[Q2NKK7_HUMAN|Unreviewed]SubName: Full=KLHL21 protein {ECO:0000313|EMBL:AAI11767.1}; SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000480631};"]
[9904,"'RBM19'",583,585,568,578.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0045292///mRNA cis splicing, via spliceosome+++GO:0040019///positive regulation of embryonic development+++GO:0007275///multicellular organism development+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 19","[RBM19_HUMAN|Reviewed]RecName: Full=Probable RNA-binding protein 19; AltName: Full=RNA-binding motif protein 19;+++[A0A024RBL4_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 19, isoform CRA_a {ECO:0000313|EMBL:EAW98063.1};+++[H0YIL2_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein 19 {ECO:0000313|Ensembl:ENSP00000449604}; Flags: Fragment;"]
[9905,"'SGSM2'",2642,2667,2669,2659.33333333333,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0042470///melanosome","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:0034499///late endosome to Golgi transport+++GO:0090630///activation of GTPase activity+++GO:0043547///positive regulation of GTPase activity","small G protein signaling modulator 2","[SGSM2_HUMAN|Reviewed]RecName: Full=Small G protein signaling modulator 2; AltName: Full=RUN and TBC1 domain-containing protein 1;+++[B9A6J3_HUMAN|Unreviewed]SubName: Full=RUN and TBC1 domain-containing protein 1 {ECO:0000313|EMBL:BAH16621.1};+++[I3L1Y7_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000459218};+++[I3L361_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000460205}; Flags: Fragment;+++[I3NI18_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000461820}; Flags: Fragment;+++[J3QSA2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000464593}; Flags: Fragment;+++[V9GYD2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476637}; Flags: Fragment;+++[V9GYJ0_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476800};"]
[9906,"'SLC35E2A'",679.65,628.55,651.5,653.233333333333,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0006468///protein phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0006915///apoptotic process+++GO:0050684///regulation of mRNA processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0001558///regulation of cell growth","solute carrier family 35 member E2A","[S35E2_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member E2;"]
[9907,"'AP5Z1'",909.03,983,1033.01,975.013333333333,null,"H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005634///nucleus+++GO:0044599///AP-5 adaptor complex+++GO:0005737///cytoplasm+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006974///cellular response to DNA damage stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0015031///protein transport+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0016197///endosomal transport","adaptor related protein complex 5 subunit zeta 1","[AP5Z1_HUMAN|Reviewed]RecName: Full=AP-5 complex subunit zeta-1; AltName: Full=Adaptor-related protein complex 5 zeta subunit; Short=Zeta5;+++[A0A024R817_HUMAN|Unreviewed]SubName: Full=KIAA0415 protein, isoform CRA_d {ECO:0000313|EMBL:EAW87298.1};+++[A4D1Z4_HUMAN|Unreviewed]SubName: Full=KIAA0415 gene product {ECO:0000313|EMBL:EAL23965.1};"]
[9908,"'G3BP2'",2290,2164,1694,2049.33333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003676///nucleic acid binding+++GO:0030159///receptor signaling complex scaffold activity","GO:0034063///stress granule assembly+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0051028///mRNA transport+++GO:0007265///Ras protein signal transduction","G3BP stress granule assembly factor 2","[G3BP2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 2; Short=G3BP-2; AltName: Full=GAP SH3 domain-binding protein 2;+++[A0A024RDB2_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX05747.1};+++[A0A024RDE5_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAX05746.1};+++[D6R9A4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423245}; Flags: Fragment;+++[D6R9X5_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422830}; Flags: Fragment;+++[D6RAC7_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422748}; Flags: Fragment;+++[D6RB17_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424522}; Flags: Fragment;+++[D6RBM9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424060}; Flags: Fragment;+++[D6RBR0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422614}; Flags: Fragment;+++[D6RBW8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423960}; Flags: Fragment;+++[D6RE13_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000425122}; Flags: Fragment;+++[D6REX8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000421621}; Flags: Fragment;+++[D6RGJ4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426311}; Flags: Fragment;+++[H0YAE3_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426843}; Flags: Fragment;"]
[9909,"'DENND4B'",708,714,646,689.333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032483///regulation of Rab protein signal transduction","DENN domain containing 4B","[DEN4B_HUMAN|Reviewed]RecName: Full=DENN domain-containing protein 4B;+++[E9PAK5_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000357635}; Flags: Fragment;+++[H0YEF0_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000435709}; Flags: Fragment;"]
[991,"'CDC20'",29,21,34,28,"04110///Cell cycle+++04111///Cell cycle - yeast+++05203///Viral carcinogenesis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis+++04114///Oocyte meiosis",null,"M00389///APC/C complex",null,"GO:0005680///anaphase-promoting complex+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005819///spindle+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0010997///anaphase-promoting complex binding+++GO:0005515///protein binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:0042826///histone deacetylase binding+++GO:0019899///enzyme binding+++GO:0008022///protein C-terminus binding","GO:0016579///protein deubiquitination+++GO:0050773///regulation of dendrite development+++GO:0051301///cell division+++GO:0090307///mitotic spindle assembly+++GO:0090129///positive regulation of synapse maturation+++GO:0040020///regulation of meiotic nuclear division+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0007399///nervous system development+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0007049///cell cycle+++GO:0031915///positive regulation of synaptic plasticity+++GO:0007094///mitotic spindle assembly checkpoint+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0030154///cell differentiation+++GO:0016567///protein ubiquitination+++GO:0007064///mitotic sister chromatid cohesion+++GO:0008284///positive regulation of cell proliferation","cell division cycle 20","[CDC20_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 20 homolog; AltName: Full=p55CDC;"]
[9910,"'RABGAP1L'",1446,991.03,801,1079.34333333333,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005929///cilium+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:1902017///regulation of cilium assembly+++GO:0090630///activation of GTPase activity+++GO:0032880///regulation of protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0006897///endocytosis+++GO:0015031///protein transport","RAB GTPase activating protein 1 like","[RBG10_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like, isoform 10;+++[RBG1L_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like;+++[A0A0C4DG54_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000403136}; Flags: Fragment;+++[A0A0U1RQT5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489163}; Flags: Fragment;+++[A0A0U1RQV7_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489188}; Flags: Fragment;+++[A0A0U1RQX4_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489213}; Flags: Fragment;+++[A0A0U1RQY6_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489232};+++[A0A0U1RRM5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489605};+++[E9PNV2_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000432734};+++[E9PS63_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000435911}; Flags: Fragment;+++[F1LJ00_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 18 {ECO:0000313|EMBL:BAH16647.1};+++[F5H8L0_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000375916};+++[Q9Y3L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAB41265.1}; Flags: Fragment;"]
[9911,"'TMCC2'",980,799,786,855,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0042982///amyloid precursor protein metabolic process","transmembrane and coiled-coil domain family 2","[TMCC2_HUMAN|Reviewed]RecName: Full=Transmembrane and coiled-coil domains protein 2; AltName: Full=Cerebral protein 11;+++[A0A0C4DFR1_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000331842};+++[A0A1B0GUZ3_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_a {ECO:0000313|EMBL:EAW91545.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000490308};+++[G5E963_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_b {ECO:0000313|EMBL:EAW91546.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000329436};+++[Q8IW47_HUMAN|Unreviewed]SubName: Full=TMCC2 protein {ECO:0000313|EMBL:AAH41019.1}; Flags: Fragment;"]
[9912,"'ARHGAP44'",242,192,176,203.333333333333,"03013///RNA transport+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0042995///cell projection+++GO:0055037///recycling endosome+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine+++GO:0005829///cytosol+++GO:0031256///leading edge membrane+++GO:0030054///cell junction+++GO:0048786///presynaptic active zone+++GO:0005768///endosome","GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding","GO:0043547///positive regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0007165///signal transduction+++GO:0098886///modification of dendritic spine+++GO:0099010///modification of postsynaptic structure+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0006887///exocytosis+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099152///regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 44","[RHG44_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 44; AltName: Full=NPC-A-10; AltName: Full=Rho-type GTPase-activating protein RICH2; AltName: Full=RhoGAP interacting with CIP4 homologs protein 2; Short=RICH-2;+++[A0A087WZS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000482851};+++[A0A2X0U4K4_HUMAN|Unreviewed]SubName: Full=ARHGAP44 {ECO:0000313|EMBL:SPT35710.1}; Flags: Fragment;+++[E7ERK8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000262444};+++[F5H6L3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000437542};+++[J3KRS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000462141};+++[J3QQU7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000463905}; Flags: Fragment;+++[K7EK86_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000465509}; Flags: Fragment;+++[Q69Z00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp564G2272 {ECO:0000313|EMBL:CAH10728.1}; Flags: Fragment;+++[Q8TBK1_HUMAN|Unreviewed]SubName: Full=RICH2 protein {ECO:0000313|EMBL:AAH22452.3}; Flags: Fragment;"]
[9913,"'SUPT7L'",822,854,810,828.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex","GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0046982///protein heterodimerization activity","GO:0043966///histone H3 acetylation+++GO:0051457///maintenance of protein location in nucleus+++GO:1903508///positive regulation of nucleic acid-templated transcription","SPT7 like, STAGA complex gamma subunit","[ST65G_HUMAN|Reviewed]RecName: Full=STAGA complex 65 subunit gamma; AltName: Full=Adenocarcinoma antigen ART1; AltName: Full=SPTF-associated factor 65 gamma; Short=STAF65gamma; AltName: Full=Suppressor of Ty 7-like;"]
[9914,"'ATP2C2'",3,2,6,3.66666666666667,null,"H00844///Familial benign chronic pemphigus",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005388///calcium-transporting ATPase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0015410///manganese-transporting ATPase activity+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0090280///positive regulation of calcium ion import+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0006874///cellular calcium ion homeostasis+++GO:0070588///calcium ion transmembrane transport+++GO:0006816///calcium ion transport+++GO:0006811///ion transport+++GO:1902600///proton transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0061180///mammary gland epithelium development","ATPase secretory pathway Ca2+ transporting 2","[AT2C2_HUMAN|Reviewed]RecName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000305}; Short=ATPase 2C2; EC=3.6.3.8; AltName: Full=Secretory pathway Ca(2+)-ATPase 2;+++[A0A0A0MSP0_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[B3KR57_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[H3BS90_HUMAN|Unreviewed]SubName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000313|Ensembl:ENSP00000456595}; Flags: Fragment;"]
[9915,"'ARNT2'",2631,2201,1822,2218,"05200///Pathways in cancer+++05211///Renal cell carcinoma+++05202///Transcriptional misregulation in cancer","H01797///Webb-Dattani syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0032355///response to estradiol+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006805///xenobiotic metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II","aryl hydrocarbon receptor nuclear translocator 2","[ARNT2_HUMAN|Reviewed]RecName: Full=Aryl hydrocarbon receptor nuclear translocator 2; Short=ARNT protein 2; AltName: Full=Class E basic helix-loop-helix protein 1; Short=bHLHe1;+++[A0A087WVE9_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000479393};+++[H0YKW1_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000452961}; Flags: Fragment;+++[Q7Z3A3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686M216 {ECO:0000313|EMBL:CAD97972.1};+++[Q86TN1_HUMAN|Unreviewed]SubName: Full=ARNT2 protein {ECO:0000313|EMBL:AAH51335.1};+++[X5D7T2_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56635.1};+++[X5D8U0_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform G {ECO:0000313|EMBL:AHW56413.1}; Flags: Fragment;+++[X5D9H9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform B {ECO:0000313|EMBL:AHW56648.1};+++[X5DP31_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform E {ECO:0000313|EMBL:AHW56626.1};+++[X5DP40_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56636.1};+++[X5DP87_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform F {ECO:0000313|EMBL:AHW56696.1};+++[X5DQN9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform D {ECO:0000313|EMBL:AHW56412.1}; Flags: Fragment;+++[X5DRE4_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform H {ECO:0000313|EMBL:AHW56647.1};"]
[9917,"'FAM20B'",537,560.08,510,535.693333333333,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","FAM20B, glycosaminoglycan xylosylkinase","[XYLK_HUMAN|Reviewed]RecName: Full=Glycosaminoglycan xylosylkinase; EC=2.7.1.- {ECO:0000269|PubMed:19473117}; AltName: Full=Xylose kinase;+++[A0A024R918_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 20, member B, isoform CRA_a {ECO:0000313|EMBL:EAW91036.1};+++[X6RH03_HUMAN|Unreviewed]SubName: Full=Glycosaminoglycan xylosylkinase {ECO:0000313|Ensembl:ENSP00000404005}; Flags: Fragment;"]
[9918,"'NCAPD2'",713,753,709,725,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0000799///nuclear condensin complex+++GO:0000228///nuclear chromosome+++GO:0000793///condensed chromosome+++GO:0016020///membrane+++GO:0000797///condensin core heterodimer+++GO:0005829///cytosol+++GO:0000779///condensed chromosome, centromeric region+++GO:0005737///cytoplasm","GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding","GO:0051304///chromosome separation+++GO:0010032///meiotic chromosome condensation+++GO:0007049///cell cycle+++GO:0030261///chromosome condensation+++GO:0007076///mitotic chromosome condensation+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","non-SMC condensin I complex subunit D2","[CND1_HUMAN|Reviewed]RecName: Full=Condensin complex subunit 1; AltName: Full=Chromosome condensation-related SMC-associated protein 1; AltName: Full=Chromosome-associated protein D2; Short=hCAP-D2; AltName: Full=Non-SMC condensin I complex subunit D2; AltName: Full=XCAP-D2 homolog;+++[A0PJ76_HUMAN|Unreviewed]SubName: Full=NCAPD2 protein {ECO:0000313|EMBL:AAH16913.1}; Flags: Fragment;+++[B3KMS0_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[B3KY03_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[E7EN77_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000371895}; Flags: Fragment;+++[F5GZK7_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000444377}; Flags: Fragment;+++[F5H431_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000438495};"]
[9919,"'SEC16A'",5256,5097,3806,4719.66666666667,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0031090///organelle membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding","GO:0007030///Golgi organization+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0043000///Golgi to plasma membrane CFTR protein transport+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0007029///endoplasmic reticulum organization+++GO:0050821///protein stabilization+++GO:0034976///response to endoplasmic reticulum stress+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0021762///substantia nigra development+++GO:0072659///protein localization to plasma membrane+++GO:0016192///vesicle-mediated transport+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0006888///ER to Golgi vesicle-mediated transport","SEC16 homolog A, endoplasmic reticulum export factor","[SC16A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec16A; AltName: Full=SEC16 homolog A;+++[A0A0C4DH09_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000277537}; Flags: Fragment;+++[A0PJ75_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH16873.1}; Flags: Fragment;+++[A4QN18_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[A4QN19_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[F1T0I1_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[G1UI25_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|EMBL:BAK64148.1}; Flags: Fragment;+++[J3KNL6_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[Q8N9G1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000317437}; SubName: Full=cDNA FLJ37437 fis, clone BRAWH2003025 {ECO:0000313|EMBL:BAC04415.1};+++[Q9BV84_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH01404.2}; Flags: Fragment;+++[X6RGP5_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;"]
[9920,"'KBTBD11'",708,849,714,757,{"$nulls":4},"GO:0031463///Cul3-RING ubiquitin ligase complex",null,"GO:0016567///protein ubiquitination","kelch repeat and BTB domain containing 11","[KBTBB_HUMAN|Reviewed]RecName: Full=Kelch repeat and BTB domain-containing protein 11; AltName: Full=Chronic myelogenous leukemia-associated protein; AltName: Full=Kelch domain-containing protein 7B;"]
[9921,"'RNF10'",2646,2764,2816,2742,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding","GO:0051865///protein autoubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031643///positive regulation of myelination+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated","ring finger protein 10","[RNF10_HUMAN|Reviewed]RecName: Full=RING finger protein 10;+++[A0A024RBP0_HUMAN|Unreviewed]SubName: Full=Ring finger protein 10, isoform CRA_a {ECO:0000313|EMBL:EAW98203.1};+++[A0A0G2JKT9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000438638}; Flags: Fragment;+++[F5H3A4_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439221}; Flags: Fragment;+++[F5H510_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000444770}; Flags: Fragment;+++[F5H5P6_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443235}; Flags: Fragment;+++[F5H5Z1_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443000};+++[H0YF69_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000437392}; Flags: Fragment;+++[H0YFN9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439510}; Flags: Fragment;+++[H0YFQ9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439859}; Flags: Fragment;+++[H0YG28_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000441487}; Flags: Fragment;+++[H0YGL7_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443790}; Flags: Fragment;+++[H0YGX5_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000445160}; Flags: Fragment;"]
[9922,"'IQSEC1'",4609,3231,2552,3464,"04144///Endocytosis","H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032012///regulation of ARF protein signal transduction+++GO:0051549///positive regulation of keratinocyte migration+++GO:0043547///positive regulation of GTPase activity+++GO:1903393///positive regulation of adherens junction organization+++GO:0030036///actin cytoskeleton organization","IQ motif and Sec7 domain 1","[IQEC1_HUMAN|Reviewed]RecName: Full=IQ motif and SEC7 domain-containing protein 1; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 100; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 2; AltName: Full=Brefeldin-resistant Arf-GEF 2 protein {ECO:0000303|PubMed:16461286}; Short=BRAG2 {ECO:0000303|PubMed:24058294};+++[A0A087WWK8_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000480301};+++[A0A0C4DGT3_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000478001};+++[A0A2R8Y695_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000495163}; Flags: Fragment;+++[A0A2R8Y7T6_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496366};+++[B4DGC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60491, highly similar to IQ motif and Sec7 domain-containing protein 1 {ECO:0000313|EMBL:BAG57736.1};+++[L0R4Y9_HUMAN|Unreviewed]SubName: Full=Alternative protein IQSEC1 {ECO:0000313|EMBL:CCO13748.1};"]
[9923,"'ZBTB40'",576,610,480,555.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0030282///bone mineralization+++GO:0006357///regulation of transcription by RNA polymerase II","zinc finger and BTB domain containing 40","[ZBT40_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 40;+++[B1AKC8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000383098}; Flags: Fragment;+++[B2RBP0_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 40, isoform CRA_a {ECO:0000313|EMBL:EAW95011.1}; SubName: Full=cDNA, FLJ95610, Homo sapiens KIAA0478 gene product (KIAA0478), mRNA {ECO:0000313|EMBL:BAG37287.1};+++[B3KR52_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33700 fis, clone BRAWH2005074, highly similar to Zinc finger and BTB domain-containing protein 40 {ECO:0000313|EMBL:BAG52264.1}; Flags: Fragment;+++[F8WAI8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000363782};+++[Q1RMZ5_HUMAN|Unreviewed]SubName: Full=ZBTB40 protein {ECO:0000313|EMBL:AAI14608.1};"]
[9924,"'PAN2'",427,290,274,330.333333333333,"03018///RNA degradation",null,"M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00010///Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate+++M00740///Methylaspartate cycle+++M00012///Glyoxylate cycle","R00351///acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing) Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate","GO:0000932///P-body+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0031251///PAN complex+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0004108///citrate (Si)-synthase activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0000175///3'-5'-exoribonuclease activity","GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0006397///mRNA processing+++GO:0005975///carbohydrate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening","poly(A) specific ribonuclease subunit PAN2","[PAN2_HUMAN|Reviewed]RecName: Full=PAN2-PAN3 deadenylation complex catalytic subunit PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}; EC=3.1.13.4 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 52 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=PAB1P-dependent poly(A)-specific ribonuclease {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Poly(A)-nuclease deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182}; Short=PAN deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182};"]
[9925,"'ZBTB5'",359,384,295,346,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus","zinc finger and BTB domain containing 5","[ZBTB5_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 5;+++[Q5T942_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 5 {ECO:0000313|EMBL:EAW58282.1}; SubName: Full=cDNA FLJ77230, highly similar to Homo sapiens zinc finger and BTB domain containing 5 (ZBTB5), mRNA {ECO:0000313|EMBL:BAF85093.1};"]
[9926,"'LPGAT1'",610,416.93,403.14,476.69,"00564///Glycerophospholipid metabolism",null,null,"R09036///acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0003674///molecular_function","GO:0006629///lipid metabolic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","lysophosphatidylglycerol acyltransferase 1","[LGAT1_HUMAN|Reviewed]RecName: Full=Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; EC=2.3.1.-;"]
[9927,"'MFN2'",2012,1953,1960,1975,"04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway+++04214///Apoptosis - fly","H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0031306///intrinsic component of mitochondrial outer membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton","GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0001825///blastocyst formation+++GO:0007050///cell cycle arrest+++GO:0006986///response to unfolded protein+++GO:0007596///blood coagulation+++GO:0051646///mitochondrion localization+++GO:0006914///autophagy+++GO:0048593///camera-type eye morphogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:0016236///macroautophagy+++GO:0006626///protein targeting to mitochondrion+++GO:0008053///mitochondrial fusion+++GO:0006915///apoptotic process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0034497///protein localization to phagophore assembly site+++GO:0007006///mitochondrial membrane organization","mitofusin 2","[MFN2_HUMAN|Reviewed]RecName: Full=Mitofusin-2; EC=3.6.5.-; AltName: Full=Transmembrane GTPase MFN2;+++[Q5JXC5_HUMAN|Unreviewed]SubName: Full=Mitofusin-2 {ECO:0000313|Ensembl:ENSP00000412023}; Flags: Fragment;"]
[9928,"'KIF14'",2,6,0.73,2.91,null,"H01513///Retinoblastoma+++H00261///Meckel syndrome (MKS)",null,null,"GO:0005874///microtubule+++GO:0005819///spindle+++GO:0030496///midbody+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0051233///spindle midzone+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0015631///tubulin binding+++GO:0030165///PDZ domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed","GO:0021695///cerebellar cortex development+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0032467///positive regulation of cytokinesis+++GO:0051301///cell division+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0032147///activation of protein kinase activity+++GO:0021846///cell proliferation in forebrain+++GO:0033624///negative regulation of integrin activation+++GO:0021693///cerebellar Purkinje cell layer structural organization+++GO:0021772///olfactory bulb development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0030155///regulation of cell adhesion+++GO:0007080///mitotic metaphase plate congression+++GO:0021766///hippocampus development+++GO:0032487///regulation of Rap protein signal transduction+++GO:0043523///regulation of neuron apoptotic process+++GO:0007019///microtubule depolymerization+++GO:0045184///establishment of protein localization+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0021685///cerebellar granular layer structural organization+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0008284///positive regulation of cell proliferation+++GO:0031641///regulation of myelination+++GO:0007018///microtubule-based movement+++GO:0030334///regulation of cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0021987///cerebral cortex development+++GO:1903429///regulation of cell maturation+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process","kinesin family member 14","[KIF14_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF14 {ECO:0000305};"]
[9929,"'JOSD1'",818,710,731,753,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","Josephin domain containing 1","[JOS1_HUMAN|Reviewed]RecName: Full=Josephin-1; EC=3.4.19.12; AltName: Full=Josephin domain-containing protein 1;+++[A0A024R1P5_HUMAN|Unreviewed]SubName: Full=Josephin domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW60260.1};+++[B0QY55_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000393131}; Flags: Fragment;+++[B0QY56_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000410010}; Flags: Fragment;+++[B0QY57_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000415189}; Flags: Fragment;+++[B0QY58_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000405182}; Flags: Fragment;+++[H0YGT9_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000444798}; Flags: Fragment;"]
[993,"'CDC25A'",17,19,13,16.3333333333333,"05206///MicroRNAs in cancer+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04218///Cellular senescence",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0051087///chaperone binding","GO:0007049///cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016579///protein deubiquitination+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0009314///response to radiation+++GO:0034644///cellular response to UV","cell division cycle 25A","[MPIP1_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 1; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25A;+++[A0A024R2R6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_b {ECO:0000313|EMBL:EAW64852.1};+++[A0A024R2S4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_a {ECO:0000313|EMBL:EAW64851.1};+++[C9JFR5_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000416483}; Flags: Fragment;+++[C9JH94_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000404285}; Flags: Fragment;+++[D8KXX0_HUMAN|Unreviewed]SubName: Full=CDC25A2-CAG isoform {ECO:0000313|EMBL:ACI43572.1};+++[K7N7S0_HUMAN|Unreviewed]SubName: Full=CDC25 isoform A1-CAG {ECO:0000313|EMBL:ACZ05628.1};"]
[9931,"'HELZ'",842,789,602,744.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043186///P granule+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding","GO:0035194///posttranscriptional gene silencing by RNA","helicase with zinc finger","[HELZ_HUMAN|Reviewed]RecName: Full=Probable helicase with zinc finger domain; EC=3.6.4.-; AltName: Full=Down-regulated in human cancers protein;+++[A0A024R8K8_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger, isoform CRA_a {ECO:0000313|EMBL:EAW89024.1};+++[A0A075B6R3_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000411144};+++[A0A2P0H7U5_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger {ECO:0000313|EMBL:AAI30583.1};+++[B7ZLW2_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAI44084.1};+++[C1KEM4_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49579.1}; Flags: Fragment;+++[C1KEM5_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49580.1}; Flags: Fragment;+++[J3KS59_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462320}; Flags: Fragment;+++[J3KT20_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462763}; Flags: Fragment;+++[J3QRR8_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464354}; Flags: Fragment;+++[J3QS41_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464512};+++[Q6PGP6_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAH56895.1}; Flags: Fragment;"]
[9933,"'PUM3'",469,483,371,441,{"$nulls":4},"GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0010835///regulation of protein ADP-ribosylation","pumilio RNA binding family member 3","[PUM3_HUMAN|Reviewed]RecName: Full=Pumilio homolog 3 {ECO:0000305}; AltName: Full=HBV X-transactivated gene 5 protein; AltName: Full=HBV XAg-transactivated protein 5; AltName: Full=Minor histocompatibility antigen HA-8; Short=HLA-HA8;+++[Q9NYH5_HUMAN|Unreviewed]SubName: Full=KIAA0020 protein {ECO:0000313|EMBL:AAF69838.1}; Flags: Fragment;+++[S4R3K8_HUMAN|Unreviewed]SubName: Full=Pumilio homolog 3 {ECO:0000313|Ensembl:ENSP00000474467}; Flags: Fragment;"]
[9934,"'P2RY14'",0,0,3,1,"04080///Neuroactive ligand-receptor interaction","H00889///MED12-related disorders+++H01795///Blepharophimosis-mental retardation syndrome (BMRS)+++H00894///FG syndrome (FGS)+++H01640///Uterine leiomyoma",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0004930///G protein-coupled receptor activity+++GO:0045028///G protein-coupled purinergic nucleotide receptor activity+++GO:0045029///UDP-activated nucleotide receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0035589///G protein-coupled purinergic nucleotide receptor signaling pathway","purinergic receptor P2Y14","[P2Y14_HUMAN|Reviewed]RecName: Full=P2Y purinoceptor 14; Short=P2Y14; AltName: Full=G-protein coupled receptor 105; AltName: Full=UDP-glucose receptor;+++[A5JUU3_HUMAN|Unreviewed]SubName: Full=Purinergic receptor P2Y G-protein coupled 14 transcript variant 2 {ECO:0000313|EMBL:ABQ52420.1}; SubName: Full=Purinergic receptor P2Y, G-protein coupled, 14, isoform CRA_a {ECO:0000313|EMBL:EAW78809.1}; SubName: Full=cDNA FLJ75398, highly similar to Homo sapiens purinergic receptor P2Y, G-protein coupled, 14, mRNA {ECO:0000313|EMBL:BAF82306.1};+++[C9JAB5_HUMAN|Unreviewed]SubName: Full=P2Y purinoceptor 14 {ECO:0000313|Ensembl:ENSP00000418065}; Flags: Fragment;"]
[9935,"'MAFB'",53,75,46,58,"04928///Parathyroid hormone synthesis, secretion and action","H01865///Multicentric carpotarsal osteolysis syndrome",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0007379///segment specification+++GO:0007585///respiratory gaseous exchange+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042472///inner ear morphogenesis+++GO:0021571///rhombomere 5 development+++GO:0021572///rhombomere 6 development+++GO:0007423///sensory organ development+++GO:0033077///T cell differentiation in thymus+++GO:0035284///brain segmentation+++GO:0021599///abducens nerve formation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0048538///thymus development","MAF bZIP transcription factor B","[MAFB_HUMAN|Reviewed]RecName: Full=Transcription factor MafB; Short=Maf-B; AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog B;+++[L8ECC4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAFB {ECO:0000313|EMBL:CCQ43322.1};"]
[9936,"'CD302'",208.64,151,186,181.88,{"$nulls":4},"GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005902///microvillus+++GO:0030175///filopodium+++GO:0005938///cell cortex+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0006909///phagocytosis","CD302 molecule","[CD302_HUMAN|Reviewed]RecName: Full=CD302 antigen; AltName: Full=C-type lectin BIMLEC; AltName: Full=C-type lectin domain family 13 member A; AltName: Full=DEC205-associated C-type lectin 1; AltName: Full=Type I transmembrane C-type lectin receptor DCL-1; AltName: CD_antigen=CD302; Flags: Precursor;+++[A0A087WT00_HUMAN|Unreviewed]SubName: Full=CD302 antigen {ECO:0000313|Ensembl:ENSP00000451446};"]
[9937,"'DCLRE1A'",94,93,105,97.3333333333333,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0003684///damaged DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0051301///cell division+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0007049///cell cycle","DNA cross-link repair 1A","[DCR1A_HUMAN|Reviewed]RecName: Full=DNA cross-link repair 1A protein; AltName: Full=SNM1 homolog A; Short=hSNM1; Short=hSNM1A;"]
[9938,"'ARHGAP25'",3,4,8,5,{"$nulls":4},"GO:0005829///cytosol+++GO:0001891///phagocytic cup","GO:0005096///GTPase activator activity","GO:0006911///phagocytosis, engulfment+++GO:0007165///signal transduction+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007015///actin filament organization+++GO:0051056///regulation of small GTPase mediated signal transduction","Rho GTPase activating protein 25","[RHG25_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 25; AltName: Full=Rho-type GTPase-activating protein 25;+++[A0A2X0TVS2_HUMAN|Unreviewed]SubName: Full=ARHGAP25 {ECO:0000313|EMBL:SPT35696.1}; Flags: Fragment;+++[B7Z8K7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417283}; SubName: Full=cDNA FLJ59112, highly similar to Rho-GTPase-activating protein 25 {ECO:0000313|EMBL:BAH13993.1};+++[C9JB56_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417467};+++[F8WAV9_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417425};+++[F8WDF6_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000420427};+++[H7C4P1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417818}; Flags: Fragment;+++[V9HWC8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 308 {ECO:0000313|EMBL:ACJ13710.1}; SubName: Full=Rho GTPase activating protein 25, isoform CRA_b {ECO:0000313|EMBL:EAW99867.1};"]
[9939,"'RBM8A'",1296,1307,1381,1328,"03015///mRNA surveillance pathway+++03040///Spliceosome+++03013///RNA transport","H01847///Thrombocytopenia-absent radius syndrome","M00430///Exon junction complex (EJC)",null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0071013///catalytic step 2 spliceosome+++GO:0035145///exon-exon junction complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding","GO:0031124///mRNA 3'-end processing+++GO:0006417///regulation of translation+++GO:0006396///RNA processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0051028///mRNA transport+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006406///mRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","RNA binding motif protein 8A","[RBM8A_HUMAN|Reviewed]RecName: Full=RNA-binding protein 8A; AltName: Full=Binder of OVCA1-1; Short=BOV-1; AltName: Full=RNA-binding motif protein 8A; AltName: Full=RNA-binding protein Y14; AltName: Full=Ribonucleoprotein RBM8A;+++[A0A023T787_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239};+++[A0A060D9J6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 8A {ECO:0000313|EMBL:AIB06359.1}; Flags: Fragment;+++[A0A0J9YW13_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239}; Flags: Fragment;+++[L8E9A7_HUMAN|Unreviewed]SubName: Full=Alternative protein RBM8A {ECO:0000313|EMBL:CCQ43301.1};"]
[994,"'CDC25B'",237,301,214,250.666666666667,"04110///Cell cycle+++05206///MicroRNAs in cancer+++04010///MAPK signaling pathway+++04914///Progesterone-mediated oocyte maturation",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0001556///oocyte maturation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0007144///female meiosis I+++GO:0007049///cell cycle+++GO:0000278///mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0006468///protein phosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0051301///cell division+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0032467///positive regulation of cytokinesis","cell division cycle 25B","[MPIP2_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 2; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25B;+++[B3KS38_HUMAN|Unreviewed]SubName: Full=HCG39252, isoform CRA_g {ECO:0000313|EMBL:EAX10500.1}; SubName: Full=Isoform CDC25B6 {ECO:0000313|EMBL:CBX26628.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26628.1}; SubName: Full=cDNA FLJ35394 fis, clone SKNSH2002768, highly similar to M-PHASE INDUCER PHOSPHATASE 2 {ECO:0000313|EMBL:BAG52600.1};+++[B4DIG0_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000339125}; SubName: Full=cDNA FLJ53333, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG58472.1};+++[B4DQZ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55479, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61105.1};+++[B4DRC3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56140, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61235.1};+++[E1YMX4_HUMAN|Unreviewed]SubName: Full=Isoform CDC25B7 {ECO:0000313|EMBL:CBX26629.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26629.1};+++[G8JLH2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000368918};+++[L8E819_HUMAN|Unreviewed]SubName: Full=Alternative protein CDC25B {ECO:0000313|EMBL:CCQ43259.1};+++[O43550_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94625.1}; Flags: Fragment;+++[Q6MZW8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G14213 {ECO:0000313|EMBL:CAE45909.2}; Flags: Fragment;+++[Q7LDQ7_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94623.1}; Flags: Fragment;"]
[9940,"'DLEC1'",11,9,3,7.66666666666667,"00592///alpha-Linolenic acid metabolism+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++04146///Peroxisome+++00280///Valine, leucine and isoleucine degradation+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03320///PPAR signaling pathway+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism",null,"M00087///beta-Oxidation+++M00113///Jasmonic acid biosynthesis","R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R07953///(4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapenta-6,9,12,15,18-enoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R07891///OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R07937///(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexa-6,9,12,15,18,21-enoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA+++R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R07899///(+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA+++R07895///OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA","GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0005925///focal adhesion+++GO:0005901///caveola","GO:0003674///molecular_function+++GO:0005096///GTPase activator activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding","GO:0030900///forebrain development+++GO:0008285///negative regulation of cell proliferation+++GO:0021575///hindbrain morphogenesis+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:0008360///regulation of cell shape+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007165///signal transduction+++GO:0003007///heart morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0006915///apoptotic process+++GO:0051497///negative regulation of stress fiber assembly+++GO:0048041///focal adhesion assembly+++GO:0001843///neural tube closure+++GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity","DLEC1, cilia and flagella associated protein","[DLEC1_HUMAN|Reviewed]RecName: Full=Deleted in lung and esophageal cancer protein 1; AltName: Full=Deleted in lung cancer protein 1; Short=DLC-1;+++[A1L305_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29825.1};+++[A2VDF1_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29826.1}; Flags: Fragment;+++[B1B5Y4_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|EMBL:BAG11659.1}; Flags: Fragment;+++[B7ZW06_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 {ECO:0000313|EMBL:AAI71799.1};+++[Q32W76_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 3 {ECO:0000313|EMBL:AAX18635.1}; SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|Ensembl:ENSP00000404261}; Flags: Fragment;+++[Q32W77_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript varient 2 {ECO:0000313|EMBL:AAX18634.1}; Flags: Fragment;+++[Q32W78_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 1 {ECO:0000313|EMBL:AAX18633.1}; Flags: Fragment;"]
[9941,"'EXOG'",153,145,121,139.666666666667,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004529///exodeoxyribonuclease activity+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0008409///5'-3' exonuclease activity","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006309///apoptotic DNA fragmentation+++GO:0008150///biological_process","exo/endonuclease G","[EXOG_HUMAN|Reviewed]RecName: Full=Nuclease EXOG, mitochondrial; EC=3.1.30.-; AltName: Full=Endonuclease G-like 1; Short=Endo G-like 1; Flags: Precursor;+++[A0A024R2T8_HUMAN|Unreviewed]SubName: Full=Endonuclease G-like 1, isoform CRA_b {ECO:0000313|EMBL:EAW64539.1};+++[F2Z2D3_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000400239};+++[F8WC11_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000412756};+++[F8WE28_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000394977};+++[F8WE38_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000402164};+++[F8WEP0_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000413176};+++[H0Y8P1_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000421649}; Flags: Fragment;+++[H7C0W6_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000397124}; Flags: Fragment;+++[H7C451_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000415568}; Flags: Fragment;"]
[9942,"'XYLB'",216,123.04,119.89,152.976666666667,"00040///Pentose and glucuronate interconversions+++01100///Metabolic pathways","H00632///Heterotaxy","M00014///Glucuronate pathway (uronate pathway)","R01639///ATP:D-xylulose 5-phosphotransferase   ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0004856///xylulokinase activity","GO:0005975///carbohydrate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0005997///xylulose metabolic process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0016310///phosphorylation+++GO:0005998///xylulose catabolic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0042732///D-xylose metabolic process","xylulokinase","[XYLB_HUMAN|Reviewed]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;+++[C9J0N9_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000412282};+++[F8WBF6_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000398845};+++[Q6PIS3_HUMAN|Unreviewed]SubName: Full=XYLB protein {ECO:0000313|EMBL:AAH30231.1}; Flags: Fragment;"]
[9943,"'OXSR1'",855,907,733,831.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0042802///identical protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity","GO:0072143///mesangial cell development+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0002062///chondrocyte differentiation+++GO:1990869///cellular response to chemokine+++GO:0072207///metanephric epithelium development+++GO:0023014///signal transduction by protein phosphorylation+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:0001657///ureteric bud development+++GO:0072169///specification of posterior mesonephric tubule identity+++GO:0072168///specification of anterior mesonephric tubule identity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0072111///cell proliferation involved in kidney development+++GO:0072166///posterior mesonephric tubule development+++GO:0006979///response to oxidative stress+++GO:0001655///urogenital system development+++GO:0032147///activation of protein kinase activity+++GO:0048863///stem cell differentiation+++GO:0048793///pronephros development+++GO:0072234///metanephric nephron tubule development+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0042733///embryonic digit morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0023016///signal transduction by trans-phosphorylation+++GO:0001823///mesonephros development+++GO:0071476///cellular hypotonic response+++GO:2000543///positive regulation of gastrulation+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0038146///chemokine (C-X-C motif) ligand 12 signaling pathway+++GO:0071300///cellular response to retinoic acid+++GO:0060021///roof of mouth development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0072180///mesonephric duct morphogenesis+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:0072190///ureter urothelium development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0042474///middle ear morphogenesis+++GO:0072184///renal vesicle progenitor cell differentiation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0016310///phosphorylation+++GO:0072259///metanephric interstitial fibroblast development+++GO:0007231///osmosensory signaling pathway+++GO:0030154///cell differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072268///pattern specification involved in metanephros development+++GO:0042476///odontogenesis+++GO:0072183///negative regulation of nephron tubule epithelial cell differentiation+++GO:0008406///gonad development+++GO:0072075///metanephric mesenchyme development+++GO:0072498///embryonic skeletal joint development+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0072208///metanephric smooth muscle tissue development+++GO:0043066///negative regulation of apoptotic process+++GO:0030501///positive regulation of bone mineralization+++GO:0001656///metanephros development+++GO:0035556///intracellular signal transduction+++GO:0090094///metanephric cap mesenchymal cell proliferation involved in metanephros development+++GO:0046777///protein autophosphorylation+++GO:0048389///intermediate mesoderm development","oxidative stress responsive 1","[OXSR1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase OSR1; EC=2.7.11.1; AltName: Full=Oxidative stress-responsive 1 protein;+++[A0A024R2M7_HUMAN|Unreviewed]SubName: Full=Oxidative-stress responsive 1, isoform CRA_a {ECO:0000313|EMBL:EAW64523.1};+++[C9JIG9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000415851};+++[F8WBK9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000398356};+++[L8ECC0_HUMAN|Unreviewed]SubName: Full=Alternative protein OXSR1 {ECO:0000313|EMBL:CCQ43302.1};"]
[9945,"'GFPT2'",76,62,71,69.6666666666667,"01130///Biosynthesis of antibiotics+++00250///Alanine, aspartate and glutamate metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++04931///Insulin resistance+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome",null,"R00768///L-glutamine:D-fructose-6-phosphate isomerase (deaminating); L-glutamine:D-fructose-6-phosphate   L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate","GO:0005829///cytosol","GO:0008483///transaminase activity+++GO:0005515///protein binding+++GO:0097367///carbohydrate derivative binding+++GO:0016740///transferase activity+++GO:0004360///glutamine-fructose-6-phosphate transaminase (isomerizing) activity","GO:0006541///glutamine metabolic process+++GO:0006112///energy reserve metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:1901135///carbohydrate derivative metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:1901137///carbohydrate derivative biosynthetic process+++GO:0006487///protein N-linked glycosylation","glutamine-fructose-6-phosphate transaminase 2","[GFPT2_HUMAN|Reviewed]RecName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2; EC=2.6.1.16 {ECO:0000250|UniProtKB:P82808}; AltName: Full=D-fructose-6-phosphate amidotransferase 2; AltName: Full=Glutamine:fructose-6-phosphate amidotransferase 2; Short=GFAT 2; Short=GFAT2; AltName: Full=Hexosephosphate aminotransferase 2;+++[A0A0S2Z4W6_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 2 {ECO:0000313|EMBL:ALQ33953.1}; Flags: Fragment;+++[A0A0S2Z4X9_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 1 {ECO:0000313|EMBL:ALQ33952.1}; SubName: Full=Glutamine-fructose-6-phosphate transaminase 2, isoform CRA_b {ECO:0000313|EMBL:EAW53756.1}; Flags: Fragment;+++[B3KMR8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12445 fis, clone NT2RM1000256, highly similar to Glucosamine--fructose-6-phosphateaminotransferase (isomerizing) 2 {ECO:0000313|EMBL:BAG51080.1};+++[D6RAC1_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000422771}; Flags: Fragment;+++[E5RJP4_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000431125}; Flags: Fragment;"]
[9946,"'CRYZL1'",104,131,89,108,"04137///Mitophagy - animal+++04140///Autophagy - animal","H02132///Microcephaly syndrome",null,null,"GO:0005829///cytosol","GO:0050661///NADP binding+++GO:0016491///oxidoreductase activity+++GO:0003960///NADPH:quinone reductase activity","GO:1901661///quinone metabolic process+++GO:0055114///oxidation-reduction process","crystallin zeta like 1","[QORL1_HUMAN|Reviewed]RecName: Full=Quinone oxidoreductase-like protein 1; EC=1.-.-.-; AltName: Full=Protein 4P11; AltName: Full=Quinone oxidoreductase homolog 1; Short=QOH-1; AltName: Full=Zeta-crystallin homolog;+++[A0A0C4DG14_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000389209};+++[A6NHJ8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000355075};+++[A6NMA8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000290244};+++[A6NND8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000370951};+++[A8MZ10_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000382371};+++[C9JAL0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000405510}; Flags: Fragment;+++[C9JNR9_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000408385}; Flags: Fragment;+++[C9JQD0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000402844}; Flags: Fragment;+++[C9JZK8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399730};+++[C9K0F7_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000387660}; Flags: Fragment;+++[F8WF64_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399937};+++[H7C0X3_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000397318}; Flags: Fragment;+++[H7C2K1_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000406423}; Flags: Fragment;+++[H7C338_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000409387}; Flags: Fragment;+++[H7C3I5_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000412087}; Flags: Fragment;+++[H7C3S0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000413513}; Flags: Fragment;+++[Q8TBV9_HUMAN|Unreviewed]SubName: Full=CRYZL1 protein {ECO:0000313|EMBL:AAH22827.1}; Flags: Fragment;"]
[9948,"'WDR1'",9457,10521,10673,10217,null,"H00948///Renal hypouricemia (RHUC)",null,null,"GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection+++GO:0042643///actomyosin, actin portion+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0002102///podosome+++GO:0043209///myelin sheath+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction","GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0007605///sensory perception of sound+++GO:0045214///sarcomere organization+++GO:0030042///actin filament depolymerization+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0040011///locomotion+++GO:0002576///platelet degranulation+++GO:0030834///regulation of actin filament depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0030220///platelet formation+++GO:0002446///neutrophil mediated immunity+++GO:0008360///regulation of cell shape+++GO:0043297///apical junction assembly+++GO:0042247///establishment of planar polarity of follicular epithelium+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0030043///actin filament fragmentation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:1990266///neutrophil migration+++GO:0030865///cortical cytoskeleton organization","WD repeat domain 1","[WDR1_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 1; AltName: Full=Actin-interacting protein 1; Short=AIP1; AltName: Full=NORI-1;+++[D6RD66_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000425481}; Flags: Fragment;+++[L8E9Y5_HUMAN|Unreviewed]SubName: Full=Alternative protein WDR1 {ECO:0000313|EMBL:CCQ43551.1};+++[Q53GN4_HUMAN|Unreviewed]SubName: Full=WD repeat domain 1, isoform CRA_a {ECO:0000313|EMBL:EAW92686.1}; SubName: Full=WD repeat-containing protein 1 isoform 1 variant {ECO:0000313|EMBL:BAD96617.1}; Flags: Fragment;+++[V9HWG7_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 52 {ECO:0000313|EMBL:ACJ13729.1};"]
[9949,"'AMMECR1'",279,235,181,231.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus","GO:0005515///protein binding","GO:0008150///biological_process","Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1","[AMMR1_HUMAN|Reviewed]RecName: Full=AMME syndrome candidate gene 1 protein;+++[A0A0S2Z4V0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33954.1}; Flags: Fragment;+++[A0A0S2Z4X0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33955.1}; SubName: Full=Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region, gene 1 {ECO:0000313|EMBL:EAX02663.1}; Flags: Fragment;"]
[995,"'CDC25C'",2,0,0,0.666666666666667,"05206///MicroRNAs in cancer+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation",null,"M00693///Cell cycle - G2/M transition+++M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0016787///hydrolase activity+++GO:0004725///protein tyrosine phosphatase activity","GO:0000086///G2/M transition of mitotic cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007283///spermatogenesis+++GO:0051301///cell division+++GO:0006470///protein dephosphorylation+++GO:0008283///cell proliferation+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division","cell division cycle 25C","[MPIP3_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 3; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25C;+++[B4DX61_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56262, highly similar to M-phase inducer phosphatase 3 {ECO:0000313|EMBL:BAG63273.1};+++[D6RD20_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427105}; Flags: Fragment;+++[D6RJC2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427251}; Flags: Fragment;+++[H0Y999_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000423525}; Flags: Fragment;+++[Q9H2F0_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25C splice variant 3 {ECO:0000313|EMBL:AAG41886.1}; Flags: Fragment;"]
[9950,"'GOLGA5'",946,1001,940,962.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031985///Golgi cisterna+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005801///cis-Golgi network+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0017137///Rab GTPase binding","GO:0007030///Golgi organization+++GO:0048193///Golgi vesicle transport+++GO:0000301///retrograde transport, vesicle recycling within Golgi","golgin A5","[GOGA5_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 5; AltName: Full=Cell proliferation-inducing gene 31 protein; AltName: Full=Golgin-84; AltName: Full=Protein Ret-II; AltName: Full=RET-fused gene 5 protein;"]
[9951,"'HS3ST4'",72,115,73,86.6666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity","GO:0030201///heparan sulfate proteoglycan metabolic process","heparan sulfate-glucosamine 3-sulfotransferase 4","[HS3S4_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 4; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4; Short=3-OST-4; Short=Heparan sulfate 3-O-sulfotransferase 4; Short=h3-OST-4;+++[A5H458_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155}; Flags: Fragment;"]
[9953,"'HS3ST3B1'",395.5,607.97,420.68,474.716666666667,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0016740///transferase activity","GO:0006477///protein sulfation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification","heparan sulfate-glucosamine 3-sulfotransferase 3B1","[HS3SB_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; Short=3-OST-3B; Short=Heparan sulfate 3-O-sulfotransferase 3B1; Short=h3-OST-3B;"]
[9955,"'HS3ST3A1'",503.62,688.03,570.32,587.323333333333,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 3A1","[HS3SA_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Short=3-OST-3A; Short=Heparan sulfate 3-O-sulfotransferase 3A1; Short=h3-OST-3A;+++[J3KSX5_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9956,"'HS3ST2'",2,0,3,1.66666666666667,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0033871///[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity","GO:0007623///circadian rhythm+++GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 2","[HS3S2_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 2; EC=2.8.2.29; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2; Short=3-OST-2; Short=Heparan sulfate 3-O-sulfotransferase 2; Short=h3-OST-2;+++[H3BMR2_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9957,"'HS3ST1'",22,26,28,25.3333333333333,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0005796///Golgi lumen+++GO:0005794///Golgi apparatus","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity+++GO:0008146///sulfotransferase activity","GO:0006024///glycosaminoglycan biosynthetic process","heparan sulfate-glucosamine 3-sulfotransferase 1","[HS3S1_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Short=3-OST-1; Short=Heparan sulfate 3-O-sulfotransferase 1; Short=h3-OST-1; Flags: Precursor;+++[A0A024R9R4_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[E9PDE3_HUMAN|Unreviewed]SubName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1 {ECO:0000313|Ensembl:ENSP00000425673}; Flags: Fragment;+++[Q05CH3_HUMAN|Unreviewed]SubName: Full=HS3ST1 protein {ECO:0000313|EMBL:AAH25735.1}; Flags: Fragment;"]
[9958,"'USP15'",388,367,302,352.333333333333,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity+++GO:0061649///ubiquitin modification-dependent histone binding+++GO:0008234///cysteine-type peptidase activity","GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0006508///proteolysis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030509///BMP signaling pathway+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0016579///protein deubiquitination","ubiquitin specific peptidase 15","[UBP15_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 15; EC=3.4.19.12 {ECO:0000269|PubMed:10444327, ECO:0000269|PubMed:16005295, ECO:0000269|PubMed:21947082, ECO:0000269|PubMed:22344298, ECO:0000269|PubMed:24852371, ECO:0000269|PubMed:27368102}; AltName: Full=Deubiquitinating enzyme 15; AltName: Full=Ubiquitin thioesterase 15; AltName: Full=Ubiquitin-specific-processing protease 15; AltName: Full=Unph-2; AltName: Full=Unph4;+++[F8VVY7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000449563}; Flags: Fragment;+++[F8VZG8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446843}; Flags: Fragment;+++[F8W0H4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447603}; Flags: Fragment;+++[H0YH96_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446559}; Flags: Fragment;+++[H0YHM4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447367}; Flags: Fragment;+++[H0YI26_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448372}; Flags: Fragment;+++[H0YI31_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448393}; Flags: Fragment;+++[Q2NL66_HUMAN|Unreviewed]SubName: Full=USP15 protein {ECO:0000313|EMBL:AAI10909.1};"]
[996,"'CDC27'",1038,851,750,879.666666666667,"04111///Cell cycle - yeast+++04113///Meiosis - yeast+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0005680///anaphase-promoting complex+++GO:0005876///spindle microtubule+++GO:0016021///integral component of membrane+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019903///protein phosphatase binding+++GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0008283///cell proliferation+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle","cell division cycle 27","[CDC27_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 27 homolog; AltName: Full=Anaphase-promoting complex subunit 3; Short=APC3; AltName: Full=CDC27 homolog; Short=CDC27Hs; AltName: Full=H-NUC;+++[B4DL80_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57525, highly similar to Cell division cycle protein 27 homolog {ECO:0000313|EMBL:BAG59442.1};+++[E9PRZ6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432211};+++[F6QPS0_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432105};+++[G5EA36_HUMAN|Unreviewed]SubName: Full=Cell division cycle 27, isoform CRA_c {ECO:0000313|EMBL:EAW57688.1}; SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000437339};+++[I0EZ68_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24904.1}; Flags: Fragment;+++[I0EZ72_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24908.1}; Flags: Fragment;+++[I3L1K3_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000458904}; Flags: Fragment;+++[I3L225_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000459307}; Flags: Fragment;+++[I3L2Z8_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460061}; Flags: Fragment;+++[I3L328_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460132}; Flags: Fragment;+++[I3L394_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460279}; Flags: Fragment;+++[I3L3G1_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460424}; Flags: Fragment;+++[I3L3H6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460454}; Flags: Fragment;+++[I3L3Y5_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460830}; Flags: Fragment;+++[K7EMA6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000466424};"]
[9960,"'USP3'",218,240,210,222.666666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005654///nucleoplasm+++GO:0090543///Flemming body+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0016787///hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:1990841///promoter-specific chromatin binding+++GO:0008234///cysteine-type peptidase activity","GO:0006281///DNA repair+++GO:0031647///regulation of protein stability+++GO:0016578///histone deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0006508///proteolysis+++GO:0000122///negative regulation of transcription by RNA polymerase II","ubiquitin specific peptidase 3","[UBP3_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 3; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 3; AltName: Full=Ubiquitin thioesterase 3; AltName: Full=Ubiquitin-specific-processing protease 3;+++[H0YKU8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000452947}; Flags: Fragment;+++[H0YL81_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453093}; Flags: Fragment;+++[H0YLB7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453138};+++[H0YLG0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453194}; Flags: Fragment;+++[H0YLJ0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453228};+++[H0YM72_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453489}; Flags: Fragment;+++[H0YMI4_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};+++[H0YMP6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453688}; Flags: Fragment;+++[H0YMW1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453767};+++[H0YNK1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454043};+++[H0YNX9_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454197}; Flags: Fragment;+++[Q498Y2_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305}; Flags: Fragment;+++[Q6JHV3_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};"]
[9961,"'MVP'",2835,3476,3569,3293.33333333333,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00562///Inositol phosphate metabolism+++00564///Glycerophospholipid metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0034774///secretory granule lumen","GO:0042802///identical protein binding+++GO:0030246///carbohydrate binding+++GO:0030145///manganese ion binding+++GO:0019901///protein kinase binding+++GO:0019992///diacylglycerol binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity+++GO:0019903///protein phosphatase binding+++GO:0043178///alcohol binding","GO:0031953///negative regulation of protein autophosphorylation+++GO:0046341///CDP-diacylglycerol metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0023057///negative regulation of signaling+++GO:0015031///protein transport+++GO:0038127///ERBB signaling pathway+++GO:0051028///mRNA transport+++GO:0043312///neutrophil degranulation+++GO:0061099///negative regulation of protein tyrosine kinase activity","major vault protein","[MVP_HUMAN|Reviewed]RecName: Full=Major vault protein; Short=MVP; AltName: Full=Lung resistance-related protein;+++[Q6LAF4_HUMAN|Unreviewed]SubName: Full=LRP protein {ECO:0000313|EMBL:CAA77211.1}; Flags: Fragment;+++[X5D2M8_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform A {ECO:0000313|EMBL:AHW56524.1}; SubName: Full=Major vault protein, isoform CRA_c {ECO:0000313|EMBL:EAW79981.1}; SubName: Full=Testicular secretory protein Li 30 {ECO:0000313|EMBL:AEE61167.1}; Flags: Fragment;+++[X5D7K9_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform C {ECO:0000313|EMBL:AHW56525.1}; Flags: Fragment;+++[X5DNU0_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform B {ECO:0000313|EMBL:AHW56526.1}; Flags: Fragment;"]
[9962,"'SLC23A2'",5236,2787,2938,3653.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0009925///basal plasma membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0070890///sodium-dependent L-ascorbate transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015205///nucleobase transmembrane transporter activity","GO:0006979///response to oxidative stress+++GO:0019852///L-ascorbic acid metabolic process+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0015851///nucleobase transport","solute carrier family 23 member 2","[S23A2_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 2; AltName: Full=Na(+)/L-ascorbic acid transporter 2; AltName: Full=Nucleobase transporter-like 1 protein; AltName: Full=Sodium-dependent vitamin C transporter 2; Short=hSVCT2; AltName: Full=Yolk sac permease-like molecule 2;+++[A0A140VK48_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_b {ECO:0000313|EMBL:EAX10439.1}; SubName: Full=Testicular secretory protein Li 48 {ECO:0000313|EMBL:AEE61185.1};"]
[9963,"'SLC23A1'",4,0,5,3,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043229///intracellular organelle+++GO:0016323///basolateral plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005737///cytoplasm+++GO:0043292///contractile fiber+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005903///brush border+++GO:0009925///basal plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008520///L-ascorbate:sodium symporter activity+++GO:0005215///transporter activity+++GO:0015293///symporter activity+++GO:0005515///protein binding+++GO:0070890///sodium-dependent L-ascorbate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0033300///dehydroascorbic acid transmembrane transporter activity+++GO:0015205///nucleobase transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015081///sodium ion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0035725///sodium ion transmembrane transport+++GO:0009636///response to toxic substance+++GO:0070837///dehydroascorbic acid transport+++GO:0006811///ion transport+++GO:0019852///L-ascorbic acid metabolic process+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0015851///nucleobase transport+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0006814///sodium ion transport+++GO:0030324///lung development","solute carrier family 23 member 1","[S23A1_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 1; AltName: Full=Na(+)/L-ascorbic acid transporter 1; AltName: Full=Sodium-dependent vitamin C transporter 1; Short=hSVCT1; AltName: Full=Yolk sac permease-like molecule 3;+++[D3DVZ8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_a {ECO:0000313|EMBL:EAX10440.1};+++[H0Y544_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 2 {ECO:0000313|Ensembl:ENSP00000396364}; Flags: Fragment;+++[H0Y902_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|Ensembl:ENSP00000422688}; Flags: Fragment;+++[H0YAJ1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 1 {ECO:0000313|Ensembl:ENSP00000427271}; Flags: Fragment;+++[Q4ZGM1_HUMAN|Unreviewed]SubName: Full=Sodium-dependent vitamin C transporter 2 variant II {ECO:0000313|EMBL:AAY26157.1}; Flags: Fragment;"]
[9966,"'TNFSF15'",3,5,1.01,3.00333333333333,"04060///Cytokine-cytokine receptor interaction","H00286///Crohn's disease",null,null,"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0010469///regulation of signaling receptor activity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006915///apoptotic process+++GO:0042107///cytokine metabolic process+++GO:0006955///immune response+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007165///signal transduction","TNF superfamily member 15","[TNF15_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 15; AltName: Full=TNF ligand-related molecule 1; AltName: Full=Vascular endothelial cell growth inhibitor; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, membrane form; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, secreted form;+++[A0A0U5JA19_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 1B {ECO:0000313|EMBL:CTQ86078.1};+++[D9N2U0_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor (Ligand) superfamily, member 15 {ECO:0000313|EMBL:BAJ13472.1}; Flags: Fragment;+++[X6R8I9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 15 {ECO:0000313|Ensembl:ENSP00000363156};"]
[9967,"'THRAP3'",2105,1971,1887,1987.66666666667,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0003723///RNA binding+++GO:0042809///vitamin D receptor binding+++GO:0005515///protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0051219///phosphoprotein binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0038023///signaling receptor activity+++GO:0005524///ATP binding+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042753///positive regulation of circadian rhythm+++GO:0048255///mRNA stabilization+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0048511///rhythmic process+++GO:0008380///RNA splicing+++GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","thyroid hormone receptor associated protein 3","[TR150_HUMAN|Reviewed]RecName: Full=Thyroid hormone receptor-associated protein 3; AltName: Full=BCLAF1 and THRAP3 family member 2 {ECO:0000312|HGNC:HGNC:22964}; AltName: Full=Thyroid hormone receptor-associated protein complex 150 kDa component; Short=Trap150;+++[E9PML1_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor-associated protein 3 {ECO:0000313|Ensembl:ENSP00000433066}; Flags: Fragment;+++[Q05D20_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH19076.1}; Flags: Fragment;+++[Q6P0P7_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH65519.1}; Flags: Fragment;+++[Q6PJV4_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH10997.1}; Flags: Fragment;+++[Q7Z5U1_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH54046.1}; Flags: Fragment;"]
[9968,"'MED12'",995,1073,966,1011.33333333333,"04919///Thyroid hormone signaling pathway","H01640///Uterine leiomyoma+++H00894///FG syndrome (FGS)+++H00889///MED12-related disorders+++H01795///Blepharophimosis-mental retardation syndrome (BMRS)",null,null,"GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:1904115///axon cytoplasm+++GO:0005829///cytosol+++GO:0016592///mediator complex+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion","GO:0003682///chromatin binding+++GO:1901612///cardiolipin binding+++GO:0016787///hydrolase activity+++GO:0008017///microtubule binding+++GO:0042809///vitamin D receptor binding+++GO:0008289///lipid binding+++GO:0019904///protein domain specific binding+++GO:0070300///phosphatidic acid binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008134///transcription factor binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000287///magnesium ion binding+++GO:0003712///transcription coregulator activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003924///GTPase activity+++GO:0038023///signaling receptor activity+++GO:0019900///kinase binding+++GO:0005525///GTP binding+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0046966///thyroid hormone receptor binding","GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051602///response to electrical stimulus+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0050896///response to stimulus+++GO:0006915///apoptotic process+++GO:0014003///oligodendrocyte development+++GO:0007601///visual perception+++GO:0090398///cellular senescence+++GO:0008053///mitochondrial fusion+++GO:0048312///intracellular distribution of mitochondria+++GO:0007568///aging+++GO:0019896///axonal transport of mitochondrion+++GO:0090102///cochlea development+++GO:0060070///canonical Wnt signaling pathway+++GO:0021510///spinal cord development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0070584///mitochondrion morphogenesis+++GO:0048568///embryonic organ development+++GO:0036342///post-anal tail morphogenesis+++GO:0019827///stem cell population maintenance+++GO:0030521///androgen receptor signaling pathway+++GO:0097749///membrane tubulation+++GO:0036444///calcium import into the mitochondrion+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000002///mitochondrial genome maintenance+++GO:0016567///protein ubiquitination+++GO:0021915///neural tube development+++GO:0071333///cellular response to glucose stimulus+++GO:0007492///endoderm development+++GO:0061025///membrane fusion+++GO:0051259///protein complex oligomerization+++GO:0001843///neural tube closure+++GO:0071456///cellular response to hypoxia+++GO:0060041///retina development in camera-type eye+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0046039///GTP metabolic process+++GO:1900006///positive regulation of dendrite development+++GO:0090245///axis elongation involved in somitogenesis+++GO:0007507///heart development+++GO:0000266///mitochondrial fission+++GO:1990403///embryonic brain development+++GO:1900078///positive regulation of cellular response to insulin stimulus+++GO:0007007///inner mitochondrial membrane organization+++GO:0014044///Schwann cell development+++GO:0014850///response to muscle activity+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:1905232///cellular response to L-glutamate+++GO:0031667///response to nutrient levels+++GO:0001756///somitogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1904643///response to curcumin+++GO:0043066///negative regulation of apoptotic process+++GO:0014042///positive regulation of neuron maturation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0007005///mitochondrion organization+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0010636///positive regulation of mitochondrial fusion","mediator complex subunit 12","[MED12_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 12; AltName: Full=Activator-recruited cofactor 240 kDa component; Short=ARC240; AltName: Full=CAG repeat protein 45; AltName: Full=Mediator complex subunit 12; AltName: Full=OPA-containing protein; AltName: Full=Thyroid hormone receptor-associated protein complex 230 kDa component; Short=Trap230; AltName: Full=Trinucleotide repeat-containing gene 11 protein;+++[A0A2R8Y3X5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493673};+++[A0A2R8Y4G4_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494015}; Flags: Fragment;+++[A0A2R8Y4Q3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493988};+++[A0A2R8Y514_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494210};+++[A0A2R8Y5E2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494736}; Flags: Fragment;+++[A0A2R8Y5G3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494509};+++[A0A2R8YD53_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494273};+++[A0A2R8YDM2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494725};+++[A0A2R8YE54_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495289};+++[A0A2R8YE78_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494121};+++[A0A2R8YFD1_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495028}; Flags: Fragment;+++[A0A2R8YGE5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495943}; Flags: Fragment;+++[A8MXB6_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376232}; Flags: Fragment;+++[C9JMB8_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376231};+++[C9JY58_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000399877}; Flags: Fragment;+++[G0KYB4_HUMAN|Unreviewed]SubName: Full=Putative mediator subunit 12 short {ECO:0000313|EMBL:CAZ90628.1}; Flags: Fragment;+++[H7C141_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000398358}; Flags: Fragment;+++[H7C191_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000399084}; Flags: Fragment;+++[H7C274_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000404373}; Flags: Fragment;+++[H7C321_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000409084}; Flags: Fragment;+++[H7C3G2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000411699}; Flags: Fragment;+++[Q7Z2E0_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81050.1}; Flags: Fragment;+++[Q7Z2F1_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81080.1}; Flags: Fragment;+++[Q7Z2F4_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81020.1}; Flags: Fragment;+++[Q7Z2K3_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81092.1}; Flags: Fragment;+++[Q7Z3Z5_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000333125}; SubName: Full=Mediator of RNA polymerase II transcription, subunit 12 homolog (Yeast), isoform CRA_e {ECO:0000313|EMBL:EAX05318.1}; SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81137.1};+++[Q8WWP6_HUMAN|Unreviewed]SubName: Full=OPA-containing protein {ECO:0000313|EMBL:CAC84084.1}; Flags: Fragment;"]
[9969,"'MED13'",798,734,424,652,"04919///Thyroid hormone signaling pathway","H00550///Complete transposition of the great arteries",null,null,"GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003713///transcription coactivator activity+++GO:0042809///vitamin D receptor binding+++GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:1904168///negative regulation of thyroid hormone receptor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030521///androgen receptor signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0070328///triglyceride homeostasis+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006357///regulation of transcription by RNA polymerase II","mediator complex subunit 13","[MED13_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13; AltName: Full=Activator-recruited cofactor 250 kDa component; Short=ARC250; AltName: Full=Mediator complex subunit 13; AltName: Full=Thyroid hormone receptor-associated protein 1; AltName: Full=Thyroid hormone receptor-associated protein complex 240 kDa component; Short=Trap240; AltName: Full=Vitamin D3 receptor-interacting protein complex component DRIP250; Short=DRIP250;+++[A0A024QZ75_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000256|RuleBase:RU364134};+++[J3QRB7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000313|Ensembl:ENSP00000464131}; Flags: Fragment;"]
[997,"'CDC34'",1114,1345,1438,1299,"04120///Ubiquitin mediated proteolysis+++05168///Herpes simplex infection",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0005515///protein binding","GO:0035458///cellular response to interferon-beta+++GO:0006270///DNA replication initiation+++GO:0090261///positive regulation of inclusion body assembly+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0070848///response to growth factor+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0000209///protein polyubiquitination+++GO:0006464///cellular protein modification process+++GO:0007049///cell cycle","cell division cycle 34","[UB2R1_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 R1; EC=2.3.2.23 {ECO:0000269|PubMed:12037680, ECO:0000269|PubMed:17698585, ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:20347421}; AltName: Full=(E3-independent) E2 ubiquitin-conjugating enzyme R1; EC=2.3.2.24 {ECO:0000269|PubMed:17588522}; AltName: Full=E2 ubiquitin-conjugating enzyme R1; AltName: Full=Ubiquitin-conjugating enzyme E2-32 kDa complementing; AltName: Full=Ubiquitin-conjugating enzyme E2-CDC34; AltName: Full=Ubiquitin-protein ligase R1;+++[A0A024R1Z1_HUMAN|Unreviewed]SubName: Full=Cell division cycle 34, isoform CRA_a {ECO:0000313|EMBL:EAW61191.1};+++[U3KPV8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475282}; Flags: Fragment;+++[U3KQ77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475610}; Flags: Fragment;+++[U3KQP9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000476107}; Flags: Fragment;"]
[9970,"'NR1I3'",1,0,0,0.333333333333333,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0004882///androgen receptor activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding+++GO:0008134///transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0004887///thyroid hormone receptor activity+++GO:0003707///steroid hormone receptor activity","GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0030522///intracellular receptor signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0030154///cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030521///androgen receptor signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","nuclear receptor subfamily 1 group I member 3","[NR1I3_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group I member 3; AltName: Full=Constitutive activator of retinoid response; Short=Constitutive active response; AltName: Full=Constitutive androstane receptor; Short=CAR; AltName: Full=Orphan nuclear receptor MB67;+++[B6ZGT2_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor {ECO:0000313|EMBL:BAH02293.1};+++[B7Z8R7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000427034}; SubName: Full=cDNA FLJ56764, highly similar to Orphan nuclear receptor NR1I3 {ECO:0000313|EMBL:BAH14053.1}; SubName: Full=cDNA, FLJ79107, highly similar to Orphan nuclear receptor NR1I3 {ECO:0000313|EMBL:BAH14579.1};+++[C0H5Y2_HUMAN|Unreviewed]SubName: Full=NR1I3 protein {ECO:0000313|EMBL:AAH69651.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000424834}; SubName: Full=Nuclear receptor subfamily 1, group I, member 3, isoform CRA_c {ECO:0000313|EMBL:EAW52610.1};+++[D6REZ7_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000421588};+++[E9PCF2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000423089};+++[F1DAL4_HUMAN|Unreviewed]SubName: Full=Constitutive androstane nuclear receptor {ECO:0000313|EMBL:ADZ17385.1};+++[Q6GZ69_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV21 {ECO:0000313|EMBL:AAT47179.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000426016};+++[Q6GZ70_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV19 {ECO:0000313|EMBL:AAT47177.1}; SubName: Full=Constitutive androstane receptor SV20 {ECO:0000313|EMBL:AAT47178.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000422982};+++[Q6GZ72_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV17 {ECO:0000313|EMBL:AAT47175.1}; SubName: Full=Constitutive androstane receptor SV18 {ECO:0000313|EMBL:AAT47176.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000421374};+++[Q6GZ74_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV16 {ECO:0000313|EMBL:AAT47174.1}; Flags: Fragment;+++[Q6GZ75_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV15 {ECO:0000313|EMBL:AAT47173.1}; Flags: Fragment;+++[Q6GZ81_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV10 {ECO:0000313|EMBL:AAT47168.1}; SubName: Full=Constitutive androstane receptor SV4 {ECO:0000313|EMBL:AAT47162.1}; SubName: Full=Constitutive androstane receptor SV9 {ECO:0000313|EMBL:AAT47167.1}; SubName: Full=Nuclear receptor subfamily 1 group I member 3 {ECO:0000313|Ensembl:ENSP00000423007};+++[Q6GZ88_HUMAN|Unreviewed]SubName: Full=Constitutive androstane receptor SV2 {ECO:0000313|EMBL:AAT47160.1};"]
[9972,"'NUP153'",821,715,589,708.333333333333,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005634///nucleus+++GO:0005623///cell+++GO:0005730///nucleolus+++GO:0005643///nuclear pore+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0043657///host cell+++GO:0044613///nuclear pore central transport channel+++GO:0034399///nuclear periphery+++GO:0044615///nuclear pore nuclear basket+++GO:0016020///membrane+++GO:0042405///nuclear inclusion body","GO:0017056///structural constituent of nuclear pore+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0008139///nuclear localization sequence binding","GO:0075732///viral penetration into host nucleus+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0046718///viral entry into host cell+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0046832///negative regulation of RNA export from nucleus+++GO:0016032///viral process+++GO:0006913///nucleocytoplasmic transport","nucleoporin 153","[NU153_HUMAN|Reviewed]RecName: Full=Nuclear pore complex protein Nup153; AltName: Full=153 kDa nucleoporin; AltName: Full=Nucleoporin Nup153;+++[A0A024QZW7_HUMAN|Unreviewed]SubName: Full=Nucleoporin 153kDa, isoform CRA_a {ECO:0000313|EMBL:EAW55385.1};"]
[9973,"'CCS'",238,234,255,242.333333333333,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004784///superoxide dismutase activity+++GO:0016532///superoxide dismutase copper chaperone activity","GO:0015680///protein maturation by copper ion transfer+++GO:0034599///cellular response to oxidative stress+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0055114///oxidation-reduction process+++GO:0006801///superoxide metabolic process+++GO:0019430///removal of superoxide radicals+++GO:0030001///metal ion transport","copper chaperone for superoxide dismutase","[CCS_HUMAN|Reviewed]RecName: Full=Copper chaperone for superoxide dismutase; AltName: Full=Superoxide dismutase copper chaperone;+++[A0A024R5B4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase, isoform CRA_a {ECO:0000313|EMBL:EAW74551.1};+++[E9PK03_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000433609};+++[E9PP76_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000436379}; Flags: Fragment;+++[J3KNF4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000307870};"]
[9975,"'NR1D2'",381,359,246,328.666666666667,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex","GO:0038023///signaling receptor activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003707///steroid hormone receptor activity","GO:0042752///regulation of circadian rhythm+++GO:0050727///regulation of inflammatory response+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0033993///response to lipid+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0048511///rhythmic process+++GO:0097009///energy homeostasis+++GO:0030154///cell differentiation+++GO:0019216///regulation of lipid metabolic process+++GO:0009755///hormone-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0055088///lipid homeostasis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030522///intracellular receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0043401///steroid hormone mediated signaling pathway","nuclear receptor subfamily 1 group D member 2","[NR1D2_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group D member 2; AltName: Full=Orphan nuclear hormone receptor BD73; AltName: Full=Rev-erb alpha-related receptor; Short=RVR; AltName: Full=Rev-erb-beta; AltName: Full=V-erbA-related protein 1-related; Short=EAR-1R;+++[B4DXD3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 2 {ECO:0000313|EMBL:ADZ17342.1}; SubName: Full=Nuclear receptor subfamily 1, group D, member 2, isoform CRA_b {ECO:0000313|EMBL:EAW64341.1}; SubName: Full=cDNA FLJ51368, highly similar to Orphan nuclear receptor NR1D2 {ECO:0000313|EMBL:BAG63345.1};+++[B6ZGS3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1, group D, member 2 {ECO:0000313|EMBL:BAH02284.1};+++[F1D8P2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 1 {ECO:0000313|EMBL:ADZ17341.1};+++[Q6I9S1_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:CAG33715.1};+++[Q6NSM0_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH70035.1}; SubName: Full=Nuclear receptor subfamily 1 group D member 2 {ECO:0000313|Ensembl:ENSP00000373283};+++[Q96B66_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH15929.1}; Flags: Fragment;"]
[9976,"'CLEC2B'",0,0,1,0.333333333333333,"05167///Kaposi's sarcoma-associated herpesvirus infection",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0050776///regulation of immune response+++GO:0032199///reverse transcription involved in RNA-mediated transposition","C-type lectin domain family 2 member B","[CLC2B_HUMAN|Reviewed]RecName: Full=C-type lectin domain family 2 member B; AltName: Full=Activation-induced C-type lectin; AltName: Full=C-type lectin superfamily member 2; AltName: Full=IFN-alpha-2b-inducing-related protein 1;"]
[9978,"'RBX1'",342,374,378,364.666666666667,"04110///Cell cycle+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++04114///Oocyte meiosis+++03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04310///Wnt signaling pathway+++04341///Hedgehog signaling pathway - fly+++05200///Pathways in cancer+++04710///Circadian rhythm+++04350///TGF-beta signaling pathway+++04111///Cell cycle - yeast",null,"M00385///Cul4-DDB1-DDB2 complex+++M00407///SCF-CDC4 complex+++M00381///SCF-SKP2 complex+++M00411///SCF-GRR1 complex+++M00383///ECV complex+++M00382///SCF-FBS complex+++M00386///Cul4-DDB1-CSA complex+++M00380///SCF-BTRC complex+++M00387///SCF-FBW7 complex+++M00384///Cul3-SPOP complex+++M00379///SCF-MET30 complex",null,"GO:0005654///nucleoplasm+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0030891///VCB complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043224///nuclear SCF ubiquitin ligase complex","GO:0044877///protein-containing complex binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008134///transcription factor binding+++GO:0019788///NEDD8 transferase activity+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0046872///metal ion binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0097602///cullin family protein binding+++GO:0061630///ubiquitin protein ligase activity","GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0070911///global genome nucleotide-excision repair+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016032///viral process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006281///DNA repair+++GO:0010265///SCF complex assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006513///protein monoubiquitination+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0043687///post-translational protein modification+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0045116///protein neddylation+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000209///protein polyubiquitination+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000165///MAPK cascade+++GO:0030163///protein catabolic process","ring-box 1","[RBX1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RBX1; EC=2.3.2.27 {ECO:0000269|PubMed:11027288}; EC=2.3.2.32 {ECO:0000269|PubMed:11027288}; AltName: Full=E3 ubiquitin-protein transferase RBX1 {ECO:0000305}; AltName: Full=Protein ZYP; AltName: Full=RING finger protein 75; AltName: Full=RING-box protein 1; Short=Rbx1; AltName: Full=Regulator of cullins 1; Short=ROC1 {ECO:0000303|PubMed:10230407}; Contains: RecName: Full=E3 ubiquitin-protein ligase RBX1, N-terminally processed; AltName: Full=E3 ubiquitin-protein transferase RBX1, N-terminally processed {ECO:0000305};"]
[998,"'CDC42'",2978,3098,3042,3039.33333333333,"05131///Shigellosis+++05211///Renal cell carcinoma+++04062///Chemokine signaling pathway+++04530///Tight junction+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04810///Regulation of actin cytoskeleton+++05132///Salmonella infection+++05130///Pathogenic Escherichia coli infection+++05205///Proteoglycans in cancer+++04360///Axon guidance+++05165///Human papillomavirus infection+++05212///Pancreatic cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer+++04520///Adherens junction+++04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04011///MAPK signaling pathway - yeast+++04722///Neurotrophin signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++04912///GnRH signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04014///Ras signaling pathway+++05203///Viral carcinogenesis+++04144///Endocytosis+++04010///MAPK signaling pathway+++04370///VEGF signaling pathway+++04660///T cell receptor signaling pathway",{"$nulls":3},"GO:0045335///phagocytic vesicle+++GO:0043005///neuron projection+++GO:0005813///centrosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0030496///midbody+++GO:0000139///Golgi membrane+++GO:0045177///apical part of cell+++GO:0031256///leading edge membrane+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0070062///extracellular exosome+++GO:0005819///spindle+++GO:0051233///spindle midzone+++GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0000322///storage vacuole+++GO:0030175///filopodium+++GO:0017119///Golgi transport complex+++GO:0072686///mitotic spindle+++GO:0032991///protein-containing complex+++GO:0071944///cell periphery","GO:0004674///protein serine/threonine kinase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0005525///GTP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0031996///thioesterase binding+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0030742///GTP-dependent protein binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0032427///GBD domain binding+++GO:0019901///protein kinase binding","GO:0048013///ephrin receptor signaling pathway+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007097///nuclear migration+++GO:0060047///heart contraction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0072384///organelle transport along microtubule+++GO:0007163///establishment or maintenance of cell polarity+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0030154///cell differentiation+++GO:0031295///T cell costimulation+++GO:0090316///positive regulation of intracellular protein transport+++GO:0030031///cell projection assembly+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0030307///positive regulation of cell growth+++GO:0051489///regulation of filopodium assembly+++GO:0060997///dendritic spine morphogenesis+++GO:0031333///negative regulation of protein complex assembly+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090135///actin filament branching+++GO:0036336///dendritic cell migration+++GO:0007266///Rho protein signal transduction+++GO:0043497///regulation of protein heterodimerization activity+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0006897///endocytosis+++GO:0007088///regulation of mitotic nuclear division+++GO:0016567///protein ubiquitination+++GO:0006468///protein phosphorylation+++GO:0051491///positive regulation of filopodium assembly+++GO:0051492///regulation of stress fiber assembly+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0032467///positive regulation of cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0099563///modification of synaptic structure+++GO:0046330///positive regulation of JNK cascade+++GO:0034332///adherens junction organization+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0034613///cellular protein localization+++GO:0034329///cell junction assembly+++GO:0007399///nervous system development+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0045740///positive regulation of DNA replication+++GO:0007596///blood coagulation+++GO:0032488///Cdc42 protein signal transduction+++GO:0048664///neuron fate determination+++GO:0007229///integrin-mediated signaling pathway+++GO:0021762///substantia nigra development+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0051647///nucleus localization+++GO:0051835///positive regulation of synapse structural plasticity+++GO:0007030///Golgi organization+++GO:0010591///regulation of lamellipodium assembly+++GO:0030225///macrophage differentiation+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0046847///filopodium assembly+++GO:0051683///establishment of Golgi localization+++GO:0008360///regulation of cell shape+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0003161///cardiac conduction system development+++GO:0007264///small GTPase mediated signal transduction+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0051301///cell division+++GO:0038189///neuropilin signaling pathway+++GO:0002040///sprouting angiogenesis+++GO:0060661///submandibular salivary gland formation+++GO:0043085///positive regulation of catalytic activity","cell division cycle 42","[CDC42_HUMAN|Reviewed]RecName: Full=Cell division control protein 42 homolog; AltName: Full=G25K GTP-binding protein; Flags: Precursor;+++[A0A024RAE4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a {ECO:0000313|EMBL:EAW95004.1};+++[A0A024RAE6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_c {ECO:0000313|EMBL:EAW95009.1};+++[Q5JYX0_HUMAN|Unreviewed]SubName: Full=Cell division control protein 42 homolog {ECO:0000313|Ensembl:ENSP00000398327}; Flags: Fragment;"]
[9980,"'DOP1B'",397,378,294,356.333333333333,{"$nulls":4},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0005802///trans-Golgi network+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0050890///cognition+++GO:0007275///multicellular organism development+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","DOP1 leucine zipper like protein B","[DOP2_HUMAN|Reviewed]RecName: Full=Protein dopey-2;+++[F8W8U9_HUMAN|Unreviewed]SubName: Full=DOP1 leucine zipper-like protein B {ECO:0000313|Ensembl:ENSP00000270190}; Flags: Fragment;"]
[9982,"'FGFBP1'",2,3,1,2,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0009986///cell surface+++GO:0005576///extracellular region","GO:0017134///fibroblast growth factor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding+++GO:0019838///growth factor binding","GO:0008285///negative regulation of cell proliferation+++GO:0045743///positive regulation of fibroblast growth factor receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:1903589///positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007267///cell-cell signaling+++GO:0007165///signal transduction","fibroblast growth factor binding protein 1","[FGFP1_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor-binding protein 1; Short=FGF-BP; Short=FGF-BP1; Short=FGF-binding protein 1; Short=FGFBP-1; AltName: Full=17 kDa heparin-binding growth factor-binding protein; Short=17 kDa HBGF-binding protein; Short=HBp17; Flags: Precursor;"]
[9984,"'THOC1'",101,119,89,103,"03040///Spliceosome+++03013///RNA transport",null,"M00405///THC complex+++M00406///TREX complex",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0000347///THO complex+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000445///THO complex part of transcription export complex+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0000346///transcription export complex+++GO:0016607///nuclear speck","GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0051028///mRNA transport+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0006406///mRNA export from nucleus+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0007165///signal transduction+++GO:0008380///RNA splicing+++GO:0031297///replication fork processing+++GO:0006396///RNA processing+++GO:0000018///regulation of DNA recombination+++GO:0048297///negative regulation of isotype switching to IgA isotypes+++GO:0031124///mRNA 3'-end processing","THO complex 1","[THOC1_HUMAN|Reviewed]RecName: Full=THO complex subunit 1; Short=Tho1; AltName: Full=Nuclear matrix protein p84; Short=p84N5; AltName: Full=hTREX84;+++[A0A087WWS1_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000480460};+++[A0A087WY84_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000481599};+++[J3KRD7_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000461943};+++[J3KT14_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000462757};+++[J3QQZ3_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000463965};+++[R4GMN4_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473276}; Flags: Fragment;+++[R4GN58_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473499}; Flags: Fragment;"]
[9985,"'REC8'",4919,6526,7354,6266.33333333333,"04114///Oocyte meiosis",{"$nulls":3},"GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0030893///meiotic cohesin complex+++GO:0000800///lateral element+++GO:0005694///chromosome+++GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000795///synaptonemal complex+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0008278///cohesin complex+++GO:0001673///male germ cell nucleus+++GO:0034991///nuclear meiotic cohesin complex","GO:0003682///chromatin binding","GO:0007130///synaptonemal complex assembly+++GO:0009566///fertilization+++GO:0000724///double-strand break repair via homologous recombination+++GO:0007059///chromosome segregation+++GO:0007141///male meiosis I+++GO:0007062///sister chromatid cohesion+++GO:0072520///seminiferous tubule development+++GO:0007283///spermatogenesis+++GO:0001556///oocyte maturation+++GO:0051321///meiotic cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0007286///spermatid development+++GO:0006302///double-strand break repair+++GO:0007129///synapsis","REC8 meiotic recombination protein","[REC8_HUMAN|Reviewed]RecName: Full=Meiotic recombination protein REC8 homolog; AltName: Full=Cohesin Rec8p;+++[A0A075B715_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000452701}; Flags: Fragment;+++[H0YM87_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453506}; Flags: Fragment;+++[H0YMV7_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453763}; Flags: Fragment;"]
[9986,"'RCE1'",154,155,196,168.333333333333,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis",null,null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0016787///hydrolase activity","GO:0071586///CAAX-box protein processing+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","Ras converting CAAX endopeptidase 1","[FACE2_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 2; EC=3.4.22.-; AltName: Full=Farnesylated proteins-converting enzyme 2; Short=FACE-2; AltName: Full=Prenyl protein-specific endoprotease 2; AltName: Full=RCE1 homolog; Short=hRCE1;+++[A0A024R5B6_HUMAN|Unreviewed]SubName: Full=RCE1 homolog, prenyl protein peptidase (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW74566.1};+++[E9PI08_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436600};+++[E9PKA7_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000435409};+++[E9PPV9_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436300};+++[Q0P5W4_HUMAN|Unreviewed]SubName: Full=RCE1 protein {ECO:0000313|EMBL:AAH52622.1}; Flags: Fragment;"]
[9987,"'HNRNPDL'",1304,1261,1156,1240.33333333333,null,"H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005681///spliceosomal complex+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0043565///sequence-specific DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0034046///poly(G) binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0008143///poly(A) binding","GO:0010468///regulation of gene expression+++GO:0006396///RNA processing+++GO:0035722///interleukin-12-mediated signaling pathway","heterogeneous nuclear ribonucleoprotein D like","[HNRDL_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like; Short=hnRNP D-like; Short=hnRNP DL; AltName: Full=AU-rich element RNA-binding factor; AltName: Full=JKT41-binding protein; AltName: Full=Protein laAUF1;+++[A0A024RDF6_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_a {ECO:0000313|EMBL:EAX05891.1};+++[A0A087WU03_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like {ECO:0000313|Ensembl:ENSP00000478269};+++[A0A087WUK2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_b {ECO:0000313|EMBL:EAX05890.1};"]
[9988,"'DMTF1'",371,316,306,331,{"$nulls":4},"GO:0005829///cytosol+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0005654///nucleoplasm+++GO:0005576///extracellular region","GO:0003700///DNA-binding transcription factor activity+++GO:0005178///integrin binding+++GO:0003677///DNA binding+++GO:0005509///calcium ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0050840///extracellular matrix binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0070173///regulation of enamel mineralization+++GO:0031214///biomineral tissue development+++GO:0043687///post-translational protein modification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030198///extracellular matrix organization+++GO:0007049///cell cycle+++GO:0044267///cellular protein metabolic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0001503///ossification+++GO:0006355///regulation of transcription, DNA-templated","cyclin D binding myb like transcription factor 1","[DMTF1_HUMAN|Reviewed]RecName: Full=Cyclin-D-binding Myb-like transcription factor 1; Short=hDMTF1; AltName: Full=Cyclin-D-interacting Myb-like protein 1; Short=hDMP1;+++[A0A1D5RMP8_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000406384}; Flags: Fragment;+++[B3KMJ8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ11211 fis, clone PLACE1007955, highly similar to Homo sapiens cyclin D binding myb-like transcription factor 1 (DMTF1), mRNA {ECO:0000313|EMBL:BAG51010.1};+++[C9J4F7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000411858}; Flags: Fragment;+++[C9J8Y5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000397490}; Flags: Fragment;+++[C9JED5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000415382}; Flags: Fragment;+++[C9JFR2_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416499}; Flags: Fragment;+++[C9JGT5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416307}; Flags: Fragment;+++[C9JLR5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413722}; Flags: Fragment;+++[C9JVQ7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000393370}; Flags: Fragment;+++[C9JZZ6_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000387712}; Flags: Fragment;+++[C9K0K9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413118}; Flags: Fragment;+++[C9K0L9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000401129}; Flags: Fragment;+++[D6W5P0_HUMAN|Unreviewed]SubName: Full=Cyclin D binding myb-like transcription factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW76964.1};+++[E7EPA0_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000402627};+++[F8VXY9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000448775};+++[H7C388_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000410288}; Flags: Fragment;+++[J3KRC1_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000461920}; Flags: Fragment;+++[J3QKU5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463239}; Flags: Fragment;+++[J3QLN9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463638};+++[J3QLW3_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463735}; Flags: Fragment;"]
[9989,"'PPP4R1'",631,702,628,653.666666666667,"05200///Pathways in cancer+++05212///Pancreatic cancer+++04014///Ras signaling pathway",{"$nulls":3},"GO:0030289///protein phosphatase 4 complex","GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0050790///regulation of catalytic activity","protein phosphatase 4 regulatory subunit 1","[PP4R1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1;+++[F8WAJ9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000285124};+++[J3KRU1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462161}; Flags: Fragment;+++[J3KSB0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462399}; Flags: Fragment;+++[J3KSH2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462485};+++[J3KSS1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462621};+++[J3QL26_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463345}; Flags: Fragment;+++[J3QLA6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463459}; Flags: Fragment;+++[J3QQV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463909}; Flags: Fragment;+++[J3QRV2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000464394};+++[Q6RXQ6_HUMAN|Unreviewed]SubName: Full=Protein serine/threonine phosphatase 4 subunit {ECO:0000313|EMBL:AAS59409.1}; Flags: Fragment;"]
[999,"'CDH1'",7535,9061,6957,7851,"05218///Melanoma+++05219///Bladder cancer+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04390///Hippo signaling pathway+++04371///Apelin signaling pathway+++04015///Rap1 signaling pathway+++05216///Thyroid cancer+++05226///Gastric cancer+++04520///Adherens junction","H00032///Thyroid cancer+++H00025///Penile cancer+++H00054///Nasopharyngeal cancer+++H00018///Gastric cancer",null,null,"GO:0015629///actin cytoskeleton+++GO:0043296///apical junction complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0005913///cell-cell adherens junction+++GO:0005576///extracellular region+++GO:0016600///flotillin complex+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0098794///postsynapse+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016342///catenin complex+++GO:0005802///trans-Golgi network+++GO:0005768///endosome+++GO:0016328///lateral plasma membrane","GO:0050839///cell adhesion molecule binding+++GO:0032794///GTPase activating protein binding+++GO:0005509///calcium ion binding+++GO:0030506///ankyrin binding+++GO:0045296///cadherin binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0071681///cellular response to indole-3-methanol+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0009636///response to toxic substance+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0042307///positive regulation of protein import into nucleus+++GO:0071285///cellular response to lithium ion+++GO:0035635///entry of bacterium into host cell+++GO:0030198///extracellular matrix organization+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0072659///protein localization to plasma membrane+++GO:0031175///neuron projection development","cadherin 1","[CADH1_HUMAN|Reviewed]RecName: Full=Cadherin-1; AltName: Full=CAM 120/80; AltName: Full=Epithelial cadherin; Short=E-cadherin; AltName: Full=Uvomorulin; AltName: CD_antigen=CD324; Contains: RecName: Full=E-Cad/CTF1; Contains: RecName: Full=E-Cad/CTF2; Contains: RecName: Full=E-Cad/CTF3; Flags: Precursor;+++[A0A0U2ZQU7_HUMAN|Unreviewed]SubName: Full=E-cadherin 1 {ECO:0000313|EMBL:ALS87660.1};+++[B3GN61_HUMAN|Unreviewed]SubName: Full=Truncated E-cadherin {ECO:0000313|EMBL:ACD87624.1};+++[Q9UII7_HUMAN|Unreviewed]SubName: Full=E-cadherin {ECO:0000313|EMBL:BAA88957.1};"]
[9990,"'SLC12A6'",384,398.99,337,373.33,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00816///Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)+++H01815///Malignant migrating partial seizures in infancy+++H00606///Early infantile epileptic encephalopathy","M00425///H/ACA ribonucleoprotein complex",null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane","GO:0019901///protein kinase binding+++GO:0015377///cation:chloride symporter activity+++GO:0015293///symporter activity+++GO:0015079///potassium ion transmembrane transporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0005215///transporter activity","GO:1902476///chloride transmembrane transport+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0006884///cell volume homeostasis+++GO:0071476///cellular hypotonic response+++GO:0071477///cellular hypotonic salinity response+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0001525///angiogenesis+++GO:0055064///chloride ion homeostasis+++GO:0007268///chemical synaptic transmission+++GO:1990573///potassium ion import across plasma membrane+++GO:0006813///potassium ion transport","solute carrier family 12 member 6","[S12A6_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 6; AltName: Full=Electroneutral potassium-chloride cotransporter 3; AltName: Full=K-Cl cotransporter 3;+++[A0A024R9I5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_d {ECO:0000313|EMBL:EAW92302.1};+++[A0A024R9K8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_a {ECO:0000313|EMBL:EAW92296.1};+++[A7E2U9_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAI50585.1}; Flags: Fragment;+++[B3KXX3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46254 fis, clone TESTI4023096, highly similar to Solute carrier family 12 member 6 {ECO:0000313|EMBL:BAG54635.1};+++[H0YKE6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452771}; Flags: Fragment;+++[H0YKJ2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452828}; Flags: Fragment;+++[H0YKL8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452857}; Flags: Fragment;+++[H0YKQ8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452904};+++[H0YMQ9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_c {ECO:0000313|EMBL:EAW92298.1}; SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000453702};+++[H0YNJ5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000454037}; Flags: Fragment;+++[Q3ZCQ6_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAH51744.1};+++[Q6NSI7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6 {ECO:0000313|EMBL:AAH70107.2};"]
[9991,"'PTBP3'",472,440,316,409.333333333333,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0030154///cell differentiation+++GO:0043249///erythrocyte maturation+++GO:0006397///mRNA processing+++GO:0033119///negative regulation of RNA splicing+++GO:0008380///RNA splicing+++GO:0045595///regulation of cell differentiation+++GO:0009653///anatomical structure morphogenesis","polypyrimidine tract binding protein 3","[PTBP3_HUMAN|Reviewed]RecName: Full=Polypyrimidine tract-binding protein 3; AltName: Full=Regulator of differentiation 1; Short=Rod1;+++[A0A024R163_HUMAN|Unreviewed]SubName: Full=ROD1 regulator of differentiation 1 (S. pombe), isoform CRA_b {ECO:0000313|EMBL:EAW59101.1};+++[B1ALY4_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000388024}; Flags: Fragment;+++[X6R242_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000210227}; Flags: Fragment;"]
[9992,"'KCNE2'",1,1,0,0.666666666666667,"04971///Gastric acid secretion","H00720///Long QT syndrome+++H00731///Atrial fibrillation",null,null,"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005764///lysosome","GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0015459///potassium channel regulator activity+++GO:0005242///inward rectifier potassium channel activity","GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1902159///regulation of cyclic nucleotide-gated ion channel activity+++GO:0035690///cellular response to drug+++GO:0006813///potassium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086009///membrane repolarization+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0060306///regulation of membrane repolarization+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901979///regulation of inward rectifier potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0034765///regulation of ion transmembrane transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0086011///membrane repolarization during action potential+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:0043586///tongue development+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:0007568///aging+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086091///regulation of heart rate by cardiac conduction","potassium voltage-gated channel subfamily E regulatory subunit 2","[KCNE2_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 2; AltName: Full=MinK-related peptide 1; AltName: Full=Minimum potassium ion channel-related peptide 1; AltName: Full=Potassium channel subunit beta MiRP1;+++[Q2N1I3_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit 2 {ECO:0000313|EMBL:ABB00303.1}; Flags: Fragment;"]
[9993,"'DGCR2'",4650,5520,4950,5040,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0009887///animal organ morphogenesis+++GO:0050890///cognition+++GO:0007155///cell adhesion","DiGeorge syndrome critical region gene 2","[IDD_HUMAN|Reviewed]RecName: Full=Integral membrane protein DGCR2/IDD; Flags: Precursor;+++[B7Z3C4_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2, isoform CRA_c {ECO:0000313|EMBL:EAX03063.1}; SubName: Full=cDNA FLJ50536, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12160.1};+++[B7Z3T5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50553, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12321.1};+++[F6SYP7_HUMAN|Unreviewed]SubName: Full=Integral membrane protein DGCR2/IDD {ECO:0000313|Ensembl:ENSP00000445069};+++[Q5CZ70_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686I1730 {ECO:0000313|EMBL:CAI59783.1};+++[Q8IWC8_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2 {ECO:0000313|EMBL:AAH40500.1};"]
[9994,"'CASP8AP2'",153,98,86,112.333333333333,"04140///Autophagy - animal+++04137///Mitophagy - animal+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0016605///PML body+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0003714///transcription corepressor activity+++GO:0032184///SUMO polymer binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0002020///protease binding+++GO:0016505///peptidase activator activity involved in apoptotic process+++GO:0005123///death receptor binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0097190///apoptotic signaling pathway+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0036337///Fas signaling pathway+++GO:0006915///apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007049///cell cycle","caspase 8 associated protein 2","[C8AP2_HUMAN|Reviewed]RecName: Full=CASP8-associated protein 2; AltName: Full=FLICE-associated huge protein;+++[A0A087WTW5_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000478179};+++[A0A096LP21_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000485346}; Flags: Fragment;+++[A7E2C0_HUMAN|Unreviewed]SubName: Full=CASP8AP2 protein {ECO:0000313|EMBL:AAI50275.1};+++[L8EC81_HUMAN|Unreviewed]SubName: Full=Alternative protein CASP8AP2 {ECO:0000313|EMBL:CCQ43107.1};"]
[9997,"'SCO2'",118,141.42,204.29,154.57,null,"H01200///Fatal infantile cardioencephalomyopathy+++H02041///Myopia+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005759///mitochondrial matrix+++GO:0030016///myofibril+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane","GO:0005507///copper ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0004645///phosphorylase activity+++GO:0015035///protein disulfide oxidoreductase activity","GO:0045454///cell redox homeostasis+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0006206///pyrimidine nucleobase metabolic process+++GO:0006878///cellular copper ion homeostasis+++GO:0001654///eye development+++GO:0006825///copper ion transport+++GO:0055114///oxidation-reduction process+++GO:0006213///pyrimidine nucleoside metabolic process+++GO:0008535///respiratory chain complex IV assembly","SCO2, cytochrome c oxidase assembly protein","[SCO2_HUMAN|Reviewed]RecName: Full=Protein SCO2 homolog, mitochondrial; Flags: Precursor;+++[A0A1W2PP80_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491034}; Flags: Fragment;+++[A0A1W2PQK0_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491753}; Flags: Fragment;"]

{"sheet":"25 weeks samples","index":3,"n_rows":16230,"n_cols":14,"rows_kept":2250,"cut":true,"bounds":{"rows_first":1000,"rows_last":250,"rows_between":1000,"halvings":1}}
["Gene ID","Gene Symbol","25_weeks_1 Read Count","25_weeks_2 Read Count","25_weeks Average Read Count","KEGG Pathway Desc","KEGG Disease Desc","KEGG Module Desc","KEGG Reaction Desc","GO_C Desc","GO_F Desc","GO_P Desc","InterPro Desc","UniProt Desc"]
[1,"'A1BG'",143,93,118,"04380///Osteoclast differentiation",{"$nulls":3},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0031093///platelet alpha granule lumen+++GO:1904813///ficolin-1-rich granule lumen+++GO:0034774///secretory granule lumen+++GO:0062023///collagen-containing extracellular matrix+++GO:0072562///blood microparticle","GO:0003674///molecular_function","GO:0002576///platelet degranulation+++GO:0043312///neutrophil degranulation+++GO:0008150///biological_process","IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold+++IPR016332///Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor+++IPR003598///Immunoglobulin subtype 2+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily","[A1BG_HUMAN|Reviewed]RecName: Full=Alpha-1B-glycoprotein; AltName: Full=Alpha-1-B glycoprotein; Flags: Precursor;+++[M0R009_HUMAN|Unreviewed]SubName: Full=Alpha-1B-glycoprotein {ECO:0000313|Ensembl:ENSP00000470909}; Flags: Fragment;+++[V9HWD8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 163pA {ECO:0000313|EMBL:ACJ13639.1};"]
[10,"'NAT2'",0,1,0.5,"00983///Drug metabolism - other enzymes+++05204///Chemical carcinogenesis+++01100///Metabolic pathways+++00633///Nitrotoluene degradation+++00232///Caffeine metabolism+++01110///Biosynthesis of secondary metabolites+++01120///Microbial metabolism in diverse environments",null,null,"R11902///acetyl-CoA:hydrazine N-acetyltransferase   Acetyl-CoA + Hydrazine <=> CoA + Acetylhydrazine+++R07940///1,7-Dimethylxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil+++R08036///acetyl-CoA:2,4-diamino-6-nitrotoluene N-acetyltransferase   2,4-Diamino-6-nitrotoluene + Acetyl-CoA <=> 4-Acetamido-2-amino-6-nitrotoluene + CoA+++R08248///acetyl-CoA: isoniazid N-acetyltransferase   Acetyl-CoA + Isoniazid <=> CoA + N-Acetylisoniazid+++R08250///acetyl-CoA:acetylhydrazine N-acetyltransferase   Acetyl-CoA + Acetylhydrazine <=> CoA + N,N'-Diacetylhydrazine","GO:0005829///cytosol","GO:0004060///arylamine N-acetyltransferase activity","GO:0006805///xenobiotic metabolic process","IPR038765///Papain-like cysteine peptidase superfamily+++IPR001447///Arylamine N-acetyltransferase","[ARY2_HUMAN|Reviewed]RecName: Full=Arylamine N-acetyltransferase 2; EC=2.3.1.5; AltName: Full=Arylamide acetylase 2; AltName: Full=N-acetyltransferase type 2; Short=NAT-2; AltName: Full=Polymorphic arylamine N-acetyltransferase; Short=PNAT;+++[A4Z6T7_HUMAN|Unreviewed]SubName: Full=Arylamine N-acetyltransferase 2 {ECO:0000313|EMBL:ABF01136.1};"]
[100,"'ADA'",127,97,112,"05340///Primary immunodeficiency+++01100///Metabolic pathways+++00230///Purine metabolism","H00092///T-B-Severe combined immunodeficiencies (SCIDs)",null,"R01560///Adenosine aminohydrolase   Adenosine + H2O <=> Inosine + Ammonia+++R02556///Deoxyadenosine aminohydrolase   Deoxyadenosine + H2O <=> Deoxyinosine + Ammonia","GO:0032839///dendrite cytoplasm+++GO:0030054///cell junction+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0060205///cytoplasmic vesicle lumen+++GO:0005764///lysosome+++GO:0005615///extracellular space+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004000///adenosine deaminase activity+++GO:0001883///purine nucleoside binding+++GO:0019239///deaminase activity","GO:0046061///dATP catabolic process+++GO:0042493///response to drug+++GO:0046111///xanthine biosynthetic process+++GO:0045187///regulation of circadian sleep/wake cycle, sleep+++GO:0043103///hypoxanthine salvage+++GO:0043066///negative regulation of apoptotic process+++GO:0001889///liver development+++GO:0070244///negative regulation of thymocyte apoptotic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0033632///regulation of cell-cell adhesion mediated by integrin+++GO:0001701///in utero embryonic development+++GO:0032261///purine nucleotide salvage+++GO:0043101///purine-containing compound salvage+++GO:0030324///lung development+++GO:0002314///germinal center B cell differentiation+++GO:0030890///positive regulation of B cell proliferation+++GO:0010460///positive regulation of heart rate+++GO:0050870///positive regulation of T cell activation+++GO:0033197///response to vitamin E+++GO:0001821///histamine secretion+++GO:0045580///regulation of T cell differentiation+++GO:0002906///negative regulation of mature B cell apoptotic process+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0042542///response to hydrogen peroxide+++GO:0060169///negative regulation of adenosine receptor signaling pathway+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007155///cell adhesion+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0046101///hypoxanthine biosynthetic process+++GO:0048541///Peyer's patch development+++GO:0001890///placenta development+++GO:0048566///embryonic digestive tract development+++GO:0009117///nucleotide metabolic process+++GO:0060407///negative regulation of penile erection+++GO:0042110///T cell activation+++GO:0070256///negative regulation of mucus secretion+++GO:0042323///negative regulation of circadian sleep/wake cycle, non-REM sleep+++GO:0046638///positive regulation of alpha-beta T cell differentiation+++GO:0046103///inosine biosynthetic process+++GO:0002636///positive regulation of germinal center formation+++GO:0050728///negative regulation of inflammatory response+++GO:0048286///lung alveolus development+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0046085///adenosine metabolic process+++GO:0002686///negative regulation of leukocyte migration+++GO:0007568///aging+++GO:0043278///response to morphine+++GO:0045582///positive regulation of T cell differentiation+++GO:0001666///response to hypoxia+++GO:0001829///trophectodermal cell differentiation+++GO:0006154///adenosine catabolic process+++GO:0006157///deoxyadenosine catabolic process","IPR032466///Metal-dependent hydrolase+++IPR006650///Adenosine/AMP deaminase active site+++IPR006330///Adenosine/adenine deaminase+++IPR001365///Adenosine/AMP deaminase domain+++IPR028893///Adenosine deaminase","[ADA_HUMAN|Reviewed]RecName: Full=Adenosine deaminase; EC=3.5.4.4 {ECO:0000269|PubMed:16670267, ECO:0000269|PubMed:23193172, ECO:0000269|PubMed:8452534}; AltName: Full=Adenosine aminohydrolase;+++[A0A0S2Z381_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 1 {ECO:0000313|EMBL:ALQ33350.1}; SubName: Full=Adenosine deaminase, isoform CRA_c {ECO:0000313|EMBL:EAW75906.1}; Flags: Fragment;+++[A0A0S2Z3B9_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 3 {ECO:0000313|EMBL:ALQ33352.1}; Flags: Fragment;+++[A0A0S2Z3T6_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 4 {ECO:0000313|EMBL:ALQ33353.1}; Flags: Fragment;+++[F5GWI4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform 2 {ECO:0000313|EMBL:ALQ33351.1};+++[F5GXW0_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000440946};+++[F5GYD4_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase {ECO:0000313|Ensembl:ENSP00000446464};+++[Q16073_HUMAN|Unreviewed]SubName: Full=Mutant adenosine deaminase {ECO:0000313|EMBL:AAB28742.2}; Flags: Fragment;+++[X5D767_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase isoform A {ECO:0000313|EMBL:AHW56400.1}; Flags: Fragment;"]
[1000,"'CDH2'",7545,10858,9201.5,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0005788///endoplasmic reticulum lumen+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0014704///intercalated disc+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005911///cell-cell junction+++GO:0016324///apical plasma membrane+++GO:0016342///catenin complex+++GO:0099059///integral component of presynaptic active zone membrane+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0045177///apical part of cell+++GO:0005887///integral component of plasma membrane+++GO:0005912///adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0005916///fascia adherens+++GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0042383///sarcolemma+++GO:0030864///cortical actin cytoskeleton+++GO:0044853///plasma membrane raft","GO:0008092///cytoskeletal protein binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0019901///protein kinase binding+++GO:0019903///protein phosphatase binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0042802///identical protein binding+++GO:0045294///alpha-catenin binding+++GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0060019///radial glial cell differentiation+++GO:0051146///striated muscle cell differentiation+++GO:0007416///synapse assembly+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0072659///protein localization to plasma membrane+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0034332///adherens junction organization+++GO:0048514///blood vessel morphogenesis+++GO:0043410///positive regulation of MAPK cascade+++GO:0060563///neuroepithelial cell differentiation+++GO:0021987///cerebral cortex development+++GO:0010001///glial cell differentiation+++GO:0048854///brain morphogenesis+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050770///regulation of axonogenesis+++GO:1902897///regulation of postsynaptic density protein 95 clustering+++GO:0043687///post-translational protein modification+++GO:0016477///cell migration+++GO:0097150///neuronal stem cell population maintenance+++GO:0048872///homeostasis of number of cells+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0009966///regulation of signal transduction+++GO:0098609///cell-cell adhesion+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0021537///telencephalon development+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0044267///cellular protein metabolic process","IPR014868///Cadherin prodomain+++IPR020894///Cadherin conserved site+++IPR000233///Cadherin, cytoplasmic domain+++IPR002126///Cadherin-like+++IPR015919///Cadherin-like superfamily+++IPR027397///Catenin binding domain superfamily+++IPR039808///Cadherin+++IPR030051///N-cadherin","[CADH2_HUMAN|Reviewed]RecName: Full=Cadherin-2; AltName: Full=CDw325; AltName: Full=Neural cadherin; Short=N-cadherin; AltName: CD_antigen=CD325; Flags: Precursor;+++[A0A024RC42_HUMAN|Unreviewed]SubName: Full=Cadherin 2, type 1, N-cadherin (Neuronal), isoform CRA_b {ECO:0000313|EMBL:EAX01241.1};+++[C9J126_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000412120}; Flags: Fragment;+++[C9J8J8_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000411360}; Flags: Fragment;+++[C9JMH2_HUMAN|Unreviewed]SubName: Full=Cadherin-2 {ECO:0000313|Ensembl:ENSP00000414269}; Flags: Fragment;"]
[10000,"'AKT3'",346,466,406,"04973///Carbohydrate digestion and absorption+++04150///mTOR signaling pathway+++05211///Renal cell carcinoma+++05230///Central carbon metabolism in cancer+++05221///Acute myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++05145///Toxoplasmosis+++04910///Insulin signaling pathway+++05218///Melanoma+++05166///HTLV-I infection+++04261///Adrenergic signaling in cardiomyocytes+++05164///Influenza A+++04668///TNF signaling pathway+++05210///Colorectal cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05165///Human papillomavirus infection+++04611///Platelet activation+++04722///Neurotrophin signaling pathway+++04071///Sphingolipid signaling pathway+++04212///Longevity regulating pathway - worm+++04371///Apelin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04664///Fc epsilon RI signaling pathway+++05163///Human cytomegalovirus infection+++04024///cAMP signaling pathway+++05226///Gastric cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04550///Signaling pathways regulating pluripotency of stem cells+++04068///FoxO signaling pathway+++04062///Chemokine signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04660///T cell receptor signaling pathway+++04728///Dopaminergic synapse+++04213///Longevity regulating pathway - multiple species+++05160///Hepatitis C+++01524///Platinum drug resistance+++05222///Small cell lung cancer+++04630///Jak-STAT signaling pathway+++04510///Focal adhesion+++05200///Pathways in cancer+++04218///Cellular senescence+++04662///B cell receptor signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04917///Prolactin signaling pathway+++05225///Hepatocellular carcinoma+++05214///Glioma+++01522///Endocrine resistance+++04010///MAPK signaling pathway+++05169///Epstein-Barr virus infection+++05213///Endometrial cancer+++04931///Insulin resistance+++04920///Adipocytokine signaling pathway+++04915///Estrogen signaling pathway+++05161///Hepatitis B+++04066///HIF-1 signaling pathway+++04625///C-type lectin receptor signaling pathway+++05231///Choline metabolism in cancer+++04014///Ras signaling pathway+++05162///Measles+++04151///PI3K-Akt signaling pathway+++04926///Relaxin signaling pathway+++04012///ErbB signaling pathway+++04922///Glucagon signaling pathway+++05224///Breast cancer+++04211///Longevity regulating pathway+++05215///Prostate cancer+++04152///AMPK signaling pathway+++04914///Progesterone-mediated oocyte maturation+++05212///Pancreatic cancer+++04022///cGMP-PKG signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05220///Chronic myeloid leukemia+++04620///Toll-like receptor signaling pathway+++04725///Cholinergic synapse+++04072///Phospholipase D signaling pathway+++04210///Apoptosis+++05152///Tuberculosis+++04140///Autophagy - animal+++05205///Proteoglycans in cancer+++05223///Non-small cell lung cancer+++04370///VEGF signaling pathway+++04919///Thyroid hormone signaling pathway+++04380///Osteoclast differentiation","H01556///Meningioma+++H01222///Cowden syndrome+++H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01909///Hypoinsulinemic hypoglycemia with hemihypertrophy (HIHGHH)+++H00420///Familial partial lipodystrophy (FPL)+++H01649///Schizophrenia+++H00027///Ovarian cancer","M00676///PI3K-Akt signaling",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0035556///intracellular signal transduction+++GO:0018105///peptidyl-serine phosphorylation+++GO:0032008///positive regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0045766///positive regulation of angiogenesis+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0045793///positive regulation of cell size+++GO:0000002///mitochondrial genome maintenance+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0048854///brain morphogenesis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0006468///protein phosphorylation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007165///signal transduction+++GO:1905653///positive regulation of artery morphogenesis","IPR039026///Protein Kinase B, pleckstrin homology domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR000719///Protein kinase domain+++IPR017892///Protein kinase, C-terminal+++IPR011009///Protein kinase-like domain superfamily+++IPR001849///Pleckstrin homology domain+++IPR011993///PH-like domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR034675///Protein kinase B gamma, catalytic domain+++IPR039029///Serine/threonine-protein kinase RAC gamma-like+++IPR000961///AGC-kinase, C-terminal","[AKT3_HUMAN|Reviewed]RecName: Full=RAC-gamma serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Protein kinase Akt-3; AltName: Full=Protein kinase B gamma; Short=PKB gamma; AltName: Full=RAC-PK-gamma; AltName: Full=STK-2;+++[F8VS91_HUMAN|Unreviewed]SubName: Full=RAC-gamma serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000447820}; Flags: Fragment;+++[Q56A86_HUMAN|Unreviewed]SubName: Full=AKT3 protein {ECO:0000313|EMBL:AAH20479.1}; Flags: Fragment;"]
[10001,"'MED6'",235,185.96,210.48,{"$nulls":4},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0000151///ubiquitin ligase complex+++GO:0070847///core mediator complex+++GO:0005654///nucleoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0003712///transcription coregulator activity+++GO:0008134///transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001128///RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0019827///stem cell population maintenance+++GO:0016567///protein ubiquitination","IPR038566///Med6 core domain superfamily+++IPR016820///Mediator complex, subunit Med6, metazoa/plant+++IPR007018///Mediator complex, subunit Med6","[MED6_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6; AltName: Full=Activator-recruited cofactor 33 kDa component; Short=ARC33; AltName: Full=Mediator complex subunit 6; Short=hMed6; AltName: Full=Renal carcinoma antigen NY-REN-28;+++[A0A087WYL7_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};+++[B4DTY4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|RuleBase:RU364143}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|RuleBase:RU364143};+++[G3V4A5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 6 {ECO:0000256|PIRNR:PIRNR023869}; AltName: Full=Mediator complex subunit 6 {ECO:0000256|PIRNR:PIRNR023869};"]
[10003,"'NAALAD2'",14,2,8,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0008236///serine-type peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0016805///dipeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity","GO:0006508///proteolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0042135///neurotransmitter catabolic process+++GO:0008152///metabolic process","IPR007484///Peptidase M28+++IPR003137///PA domain+++IPR036757///Transferrin receptor-like, dimerisation domain superfamily+++IPR007365///Transferrin receptor-like, dimerisation domain+++IPR039373///Glutamate carboxypeptidase 2-like","[NALD2_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[E9PII2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000431989}; Flags: Fragment;+++[E9PJ53_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435670}; Flags: Fragment;+++[E9PJV2_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000433710};+++[E9PKX5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000435249};+++[J3KNJ3_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase 2 {ECO:0000313|Ensembl:ENSP00000320083};+++[L8EAF7_HUMAN|Unreviewed]SubName: Full=Alternative protein NAALAD2 {ECO:0000313|EMBL:CCQ43323.1};+++[Q4G181_HUMAN|Unreviewed]SubName: Full=NAALAD2 protein {ECO:0000313|EMBL:AAH27594.1};"]
[100037417,"'DDTL'",43.91,29.77,36.84,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0016829///lyase activity",null,"IPR019829///Macrophage migration inhibitory factor, conserved site+++IPR001398///Macrophage migration inhibitory factor+++IPR014347///Tautomerase/MIF superfamily","[DDTL_HUMAN|Reviewed]RecName: Full=D-dopachrome decarboxylase-like protein; EC=4.1.1.-; AltName: Full=D-dopachrome tautomerase-like protein;+++[A0A0F7RPW6_HUMAN|Unreviewed]SubName: Full=D-dopachrome tautomerase 2 {ECO:0000313|EMBL:CCP37992.1};+++[B5MC82_HUMAN|Unreviewed]SubName: Full=D-dopachrome decarboxylase {ECO:0000313|Ensembl:ENSP00000384866};"]
[10004,"'NAALADL1'",9,2,5.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008233///peptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004180///carboxypeptidase activity+++GO:0003824///catalytic activity+++GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity","GO:0008152///metabolic process+++GO:0006508///proteolysis","IPR003137///PA domain+++IPR039373///Glutamate carboxypeptidase 2-like+++IPR007365///Transferrin receptor-like, dimerisation domain+++IPR007484///Peptidase M28+++IPR036757///Transferrin receptor-like, dimerisation domain superfamily","[NALDL_HUMAN|Reviewed]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein; Short=NAALADase L; EC=3.4.17.21; AltName: Full=100 kDa ileum brush border membrane protein; Short=I100; AltName: Full=Ileal dipeptidylpeptidase;+++[C9JFW8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000349045};+++[E9PII9_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431977};+++[E9PIU1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433892}; Flags: Fragment;+++[E9PJQ1_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435549}; Flags: Fragment;+++[E9PKG8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000433538}; Flags: Fragment;+++[E9PKR0_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431513};+++[E9PKW7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435267}; Flags: Fragment;+++[E9PLR8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000431322}; Flags: Fragment;+++[E9PRC7_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434233}; Flags: Fragment;+++[H0YDS5_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000434225}; Flags: Fragment;+++[H0YEI8_HUMAN|Unreviewed]SubName: Full=N-acetylated-alpha-linked acidic dipeptidase-like protein {ECO:0000313|Ensembl:ENSP00000435917}; Flags: Fragment;"]
[100049587,"'SIGLEC14'",3,4,3.5,{"$nulls":4},"GO:0101003///ficolin-1-rich granule membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane","GO:0030246///carbohydrate binding","GO:0043312///neutrophil degranulation+++GO:0007155///cell adhesion+++GO:0045087///innate immune response","IPR003006///Immunoglobulin/major histocompatibility complex, conserved site+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003598///Immunoglobulin subtype 2+++IPR013106///Immunoglobulin V-set domain+++IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold","[SIG14_HUMAN|Reviewed]RecName: Full=Sialic acid-binding Ig-like lectin 14; Short=Siglec-14; Flags: Precursor;"]
[10005,"'ACOT8'",525,406,465.5,"00120///Primary bile acid biosynthesis+++01100///Metabolic pathways+++04146///Peroxisome",null,"M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R03974///chenodeoxycholoyl-CoA hydrolase   Chenodeoxycholate + CoA <=> Chenodeoxycholoyl-CoA + H2O+++R07296///choloyl-CoA hydrolase   Choloyl-CoA + H2O <=> Cholic acid + CoA","GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005829///cytosol","GO:0052815///medium-chain acyl-CoA hydrolase activity+++GO:0005102///signaling receptor binding+++GO:0052816///long-chain acyl-CoA hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0033882///choloyl-CoA hydrolase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0003986///acetyl-CoA hydrolase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0016787///hydrolase activity+++GO:0016289///CoA hydrolase activity","GO:0043649///dicarboxylic acid catabolic process+++GO:0007031///peroxisome organization+++GO:0045225///negative regulation of CD4 biosynthetic process+++GO:0016032///viral process+++GO:0006637///acyl-CoA metabolic process+++GO:0006699///bile acid biosynthetic process+++GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0016559///peroxisome fission+++GO:0036109///alpha-linolenic acid metabolic process","IPR003703///Acyl-CoA thioesterase+++IPR029069///HotDog domain superfamily","[ACOT8_HUMAN|Reviewed]RecName: Full=Acyl-coenzyme A thioesterase 8; Short=Acyl-CoA thioesterase 8; EC=3.1.2.27 {ECO:0000269|PubMed:15194431, ECO:0000269|PubMed:9299485}; AltName: Full=Choloyl-coenzyme A thioesterase; AltName: Full=HIV-Nef-associated acyl-CoA thioesterase; AltName: Full=PTE-2; AltName: Full=Peroxisomal acyl-coenzyme A thioester hydrolase 1; Short=PTE-1; AltName: Full=Peroxisomal long-chain acyl-CoA thioesterase 1; AltName: Full=Thioesterase II; Short=hACTE-III; Short=hACTEIII; Short=hTE;+++[E9PIS4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000433923};+++[E9PJN0_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435581};+++[E9PMC4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000431175};+++[E9PRD4_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000434216};+++[F6VBM3_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000435115};+++[H0Y698_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000403862}; Flags: Fragment;+++[H7C5A7_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000419403}; Flags: Fragment;+++[Q6FHI2_HUMAN|Unreviewed]SubName: Full=PTE1 protein {ECO:0000313|EMBL:CAG46570.1};+++[Q9BR14_HUMAN|Unreviewed]SubName: Full=Acyl-coenzyme A thioesterase 8 {ECO:0000313|Ensembl:ENSP00000416217}; Flags: Fragment;"]
[10006,"'ABI1'",1129,1443,1286,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0030027///lamellipodium+++GO:0005783///endoplasmic reticulum+++GO:0031252///cell leading edge+++GO:0005634///nucleus+++GO:0031209///SCAR complex+++GO:0014069///postsynaptic density+++GO:0030426///growth cone+++GO:0032433///filopodium tip+++GO:0005737///cytoplasm+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0030175///filopodium+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005856///cytoskeleton","GO:0030296///protein tyrosine kinase activator activity+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0017124///SH3 domain binding+++GO:0045296///cadherin binding","GO:0048813///dendrite morphogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0072673///lamellipodium morphogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0016032///viral process+++GO:0035855///megakaryocyte development+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001756///somitogenesis+++GO:0008154///actin polymerization or depolymerization","IPR001452///SH3 domain+++IPR012849///Abl-interactor, homeo-domain homologous domain+++IPR000727///Target SNARE coiled-coil homology domain+++IPR036028///SH3-like domain superfamily+++IPR028457///ABI family+++IPR035725///Abl Interactor 1, SH3 domain+++IPR028456///Abl interactor 1","[ABI1_HUMAN|Reviewed]RecName: Full=Abl interactor 1; AltName: Full=Abelson interactor 1; Short=Abi-1; AltName: Full=Abl-binding protein 4; Short=AblBP4; AltName: Full=Eps8 SH3 domain-binding protein; Short=Eps8-binding protein; AltName: Full=Nap1-binding protein; Short=Nap1BP; AltName: Full=Spectrin SH3 domain-binding protein 1; AltName: Full=e3B1;+++[A0A0A0MRT6_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000365330};+++[B6VEX3_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 41 {ECO:0000313|EMBL:ACJ12783.1};+++[B6VEX4_HUMAN|Unreviewed]SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSP00000439646}; SubName: Full=Abl-interactor 1 variant 21 {ECO:0000313|EMBL:ACJ12784.1};+++[B6VEX5_HUMAN|Unreviewed]SubName: Full=Abl-interactor 1 variant 72 {ECO:0000313|EMBL:ACJ12785.1};+++[L8EC66_HUMAN|Unreviewed]SubName: Full=Alternative protein ABI1 {ECO:0000313|EMBL:CCQ43032.1};"]
[10007,"'GNPDA1'",538,398,468,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways",null,null,"R00765///D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing); D-glucosamine-6-phosphate   D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia","GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0043209///myelin sheath+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0060170///ciliary membrane+++GO:0034774///secretory granule lumen","GO:0016853///isomerase activity+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity+++GO:0004347///glucose-6-phosphate isomerase activity+++GO:0016787///hydrolase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0048029///monosaccharide binding+++GO:0042802///identical protein binding+++GO:0004342///glucosamine-6-phosphate deaminase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0016866///intramolecular transferase activity+++GO:0008134///transcription factor binding+++GO:0004672///protein kinase activity+++GO:0004707///MAP kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding","GO:0051156///glucose 6-phosphate metabolic process+++GO:0006096///glycolytic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0006094///gluconeogenesis+++GO:0016310///phosphorylation+++GO:0033574///response to testosterone+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0006043///glucosamine catabolic process+++GO:0032570///response to progesterone+++GO:0035556///intracellular signal transduction+++GO:0001707///mesoderm formation+++GO:0007338///single fertilization+++GO:0016055///Wnt signaling pathway+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0035902///response to immobilization stress+++GO:0042501///serine phosphorylation of STAT protein+++GO:0010595///positive regulation of endothelial cell migration+++GO:0035994///response to muscle stretch+++GO:0061621///canonical glycolysis+++GO:0043312///neutrophil degranulation+++GO:0005975///carbohydrate metabolic process+++GO:0046777///protein autophosphorylation+++GO:0007599///hemostasis+++GO:0019262///N-acetylneuraminate catabolic process+++GO:0010469///regulation of signaling receptor activity+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0000165///MAPK cascade+++GO:0050821///protein stabilization+++GO:0001701///in utero embryonic development+++GO:0046185///aldehyde catabolic process+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0046686///response to cadmium ion+++GO:0042593///glucose homeostasis+++GO:0019242///methylglyoxal biosynthetic process+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0043278///response to morphine+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006959///humoral immune response+++GO:0032355///response to estradiol+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010468///regulation of gene expression+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0007611///learning or memory+++GO:0006468///protein phosphorylation+++GO:0034101///erythrocyte homeostasis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006046///N-acetylglucosamine catabolic process","IPR037171///NagB/RpiA transferase-like+++IPR018321///Glucosamine-6-phosphate isomerase, conserved site+++IPR004547///Glucosamine-6-phosphate isomerase+++IPR006148///Glucosamine/galactosamine-6-phosphate isomerase","[GNPI1_HUMAN|Reviewed]RecName: Full=Glucosamine-6-phosphate isomerase 1; EC=3.5.99.6; AltName: Full=Glucosamine-6-phosphate deaminase 1; Short=GNPDA 1; Short=GlcN6P deaminase 1; AltName: Full=Oscillin;+++[A0A0A0MTS2_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0G2JLI6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464798}; Flags: Fragment;+++[A0A0J9YX90_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488295}; Flags: Fragment;+++[A0A0J9YXH9_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488409}; Flags: Fragment;+++[A0A0J9YXM3_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488465}; Flags: Fragment;+++[A0A0J9YXP8_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYH3_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[A0A0J9YYI8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000488871}; Flags: Fragment;+++[A0A2R8Y6C7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000495129};+++[A0A2R8YF08_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000496041}; Flags: Fragment;+++[D6R917_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000422173}; Flags: Fragment;+++[D6R9P4_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197};+++[D6RAY7_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RB13_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFF8_HUMAN|Unreviewed]RecName: Full=Glucosamine-6-phosphate isomerase {ECO:0000256|RuleBase:RU361197}; EC=3.5.99.6 {ECO:0000256|RuleBase:RU361197}; AltName: Full=Glucosamine-6-phosphate deaminase {ECO:0000256|RuleBase:RU361197}; Flags: Fragment;+++[D6RFK5_HUMAN|Unreviewed]SubName: Full=Glucosamine-6-phosphate isomerase 1 {ECO:0000313|Ensembl:ENSP00000426583}; Flags: Fragment;+++[K7EIL4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000464797}; Flags: Fragment;+++[K7ELR7_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466191}; Flags: Fragment;+++[K7ENA0_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000466851}; Flags: Fragment;+++[K7EP41_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467221}; Flags: Fragment;+++[K7EPY4_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000467590}; Flags: Fragment;+++[K7EQ48_HUMAN|Unreviewed]RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612}; EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612}; Flags: Fragment;+++[K7ERC6_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468201}; Flags: Fragment;+++[K7ERK8_HUMAN|Unreviewed]SubName: Full=Glucose-6-phosphate isomerase {ECO:0000313|Ensembl:ENSP00000468298}; Flags: Fragment;"]
[10008,"'KCNE3'",6,3,4.5,"04974///Protein digestion and absorption","H00728///Brugada syndrome (BRS)+++H00215///Periodic paralysis",null,null,"GO:0031982///vesicle+++GO:0016021///integral component of membrane+++GO:0030425///dendrite+++GO:0008076///voltage-gated potassium channel complex+++GO:0005886///plasma membrane+++GO:0043204///perikaryon+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0032809///neuronal cell body membrane","GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005515///protein binding+++GO:0005244///voltage-gated ion channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity","GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1903765///negative regulation of potassium ion export across plasma membrane+++GO:0006813///potassium ion transport+++GO:1905025///negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0071805///potassium ion transmembrane transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0006811///ion transport+++GO:0043266///regulation of potassium ion transport+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0086011///membrane repolarization during action potential+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:1902260///negative regulation of delayed rectifier potassium channel activity","IPR000369///Potassium channel, voltage-dependent, beta subunit, KCNE+++IPR005426///Potassium channel, voltage-dependent, beta subunit, KCNE3","[KCNE3_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 3; AltName: Full=MinK-related peptide 2; AltName: Full=Minimum potassium ion channel-related peptide 2; AltName: Full=Potassium channel subunit beta MiRP2;+++[E9PJQ7_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000435539}; Flags: Fragment;+++[E9PJV9_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000433697}; Flags: Fragment;+++[E9PN03_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000434890}; Flags: Fragment;+++[Q2N1I1_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3a {ECO:0000313|EMBL:ABB00304.1}; SubName: Full=Cardiac voltage-gated potassium channel accessory subunit isoform 3b {ECO:0000313|EMBL:ABB00305.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|Ensembl:ENSP00000431739}; Flags: Fragment;+++[Q6IAE6_HUMAN|Unreviewed]SubName: Full=KCNE3 protein {ECO:0000313|EMBL:CAG33490.1}; SubName: Full=Potassium voltage-gated channel subfamily E member 3 {ECO:0000313|EMBL:ABQ01240.1}; SubName: Full=Potassium voltage-gated channel, Isk-related family, member 3 {ECO:0000313|EMBL:AAI10613.1}; SubName: Full=cDNA, FLJ92142, Homo sapiens potassium voltage-gated channel, Isk-related family,member 3 (KCNE3), mRNA {ECO:0000313|EMBL:BAG34817.1};"]
[10009,"'ZBTB33'",288,467,377.5,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0003677///DNA binding+++GO:0008327///methyl-CpG binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035556///intracellular signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0016055///Wnt signaling pathway","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR000210///BTB/POZ domain","[KAISO_HUMAN|Reviewed]RecName: Full=Transcriptional regulator Kaiso; AltName: Full=Zinc finger and BTB domain-containing protein 33;+++[L8E7W8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZBTB33 {ECO:0000313|EMBL:CCQ43375.1};"]
[1001,"'CDH3'",1727,1749,1738,"04514///Cell adhesion molecules (CAMs)","H00785///Congenital hypotrichosis with juvenile macular dystrophy+++H00639///Ectodermal dysplasia, ectrodactyly, and macular dystrophy (EEM syndrome)",null,null,"GO:0005913///cell-cell adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0098794///postsynapse+++GO:0005802///trans-Golgi network+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0030027///lamellipodium+++GO:0016328///lateral plasma membrane+++GO:0016600///flotillin complex+++GO:0005768///endosome+++GO:0043296///apical junction complex+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane","GO:0030506///ankyrin binding+++GO:0042802///identical protein binding+++GO:0032794///GTPase activating protein binding+++GO:0045295///gamma-catenin binding+++GO:0005509///calcium ion binding+++GO:0050839///cell adhesion molecule binding+++GO:0045296///cadherin binding+++GO:0008013///beta-catenin binding","GO:0035635///entry of bacterium into host cell+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0072659///protein localization to plasma membrane+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0009636///response to toxic substance+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0022405///hair cycle process+++GO:0042307///positive regulation of protein import into nucleus+++GO:0051796///negative regulation of timing of catagen+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0098609///cell-cell adhesion+++GO:0071681///cellular response to indole-3-methanol+++GO:0031424///keratinization+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0010628///positive regulation of gene expression+++GO:0001895///retina homeostasis+++GO:0042060///wound healing+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0071285///cellular response to lithium ion+++GO:1902910///positive regulation of melanosome transport+++GO:0031175///neuron projection development+++GO:0007601///visual perception+++GO:0007155///cell adhesion","IPR020894///Cadherin conserved site+++IPR015919///Cadherin-like superfamily+++IPR002126///Cadherin-like+++IPR014868///Cadherin prodomain+++IPR039808///Cadherin+++IPR027397///Catenin binding domain superfamily+++IPR000233///Cadherin, cytoplasmic domain","[CADH3_HUMAN|Reviewed]RecName: Full=Cadherin-3; AltName: Full=Placental cadherin; Short=P-cadherin; Flags: Precursor;+++[B4DLF0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50795, highly similar to Cadherin-3 {ECO:0000313|EMBL:BAG59512.1};"]
[10010,"'TANK'",179,231,205,"04621///NOD-like receptor signaling pathway+++04622///RIG-I-like receptor signaling pathway",{"$nulls":3},"GO:0035631///CD40 receptor complex+++GO:0097057///TRAF2-GSTP1 complex+++GO:0005654///nucleoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0045121///membrane raft+++GO:1990604///IRE1-TRAF2-ASK1 complex+++GO:0012506///vesicle membrane+++GO:0000151///ubiquitin ligase complex+++GO:0005938///cell cortex+++GO:1990597///AIP1-IRE1 complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex","GO:0019903///protein phosphatase binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0019899///enzyme binding+++GO:0046625///sphingolipid binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005174///CD40 receptor binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035800///deubiquitinase activator activity+++GO:0019901///protein kinase binding+++GO:0044877///protein-containing complex binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0031996///thioesterase binding+++GO:0008289///lipid binding","GO:0070207///protein homotrimerization+++GO:0051291///protein heterooligomerization+++GO:1903721///positive regulation of I-kappaB phosphorylation+++GO:0016579///protein deubiquitination+++GO:0007165///signal transduction+++GO:0006915///apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:2000158///positive regulation of ubiquitin-specific protease activity+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016032///viral process+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0032743///positive regulation of interleukin-2 production+++GO:0002726///positive regulation of T cell cytokine production+++GO:0065003///protein-containing complex assembly+++GO:0070534///protein K63-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0071479///cellular response to ionizing radiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0090073///positive regulation of protein homodimerization activity+++GO:0071550///death-inducing signaling complex assembly+++GO:0043507///positive regulation of JUN kinase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1901215///negative regulation of neuron death+++GO:0051865///protein autoubiquitination+++GO:0097300///programmed necrotic cell death+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0034976///response to endoplasmic reticulum stress+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0051023///regulation of immunoglobulin secretion+++GO:0071347///cellular response to interleukin-1+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0046328///regulation of JNK cascade+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0006508///proteolysis+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0030163///protein catabolic process+++GO:0034622///cellular protein-containing complex assembly+++GO:0071356///cellular response to tumor necrosis factor+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0034351///negative regulation of glial cell apoptotic process","IPR039669///TRAF family member-associated NF-kappa-B activator+++IPR024581///Tbk1/Ikki binding domain","[TANK_HUMAN|Reviewed]RecName: Full=TRAF family member-associated NF-kappa-B activator; AltName: Full=TRAF-interacting protein; Short=I-TRAF;+++[B1AMX7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000405860}; Flags: Fragment;+++[B1AMX8_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000406524}; Flags: Fragment;+++[B1AMY1_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated factor 2 {ECO:0000313|Ensembl:ENSP00000397653}; Flags: Fragment;+++[B2R7S3_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93580, highly similar to Homo sapiens TRAF family member-associated NFKB activator (TANK), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG35920.1};+++[E5KBQ3_HUMAN|Unreviewed]SubName: Full=TRAF2 {ECO:0000313|EMBL:ADQ89802.1};+++[E7EM55_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412622};+++[E7EMT6_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000392776}; Flags: Fragment;+++[E7ENY2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000411041}; Flags: Fragment;+++[E7EQA9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000385487};+++[E7ERM9_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000388930};+++[E7EV32_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000398157}; Flags: Fragment;+++[E7EVA2_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384492};+++[E7EW82_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000384235};+++[E7EWR8_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000399934}; Flags: Fragment;+++[E9PEK1_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000410259};+++[H7BZ28_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000387439}; Flags: Fragment;+++[H7C3L4_HUMAN|Unreviewed]SubName: Full=TRAF family member-associated NF-kappa-B activator {ECO:0000313|Ensembl:ENSP00000412556}; Flags: Fragment;+++[Q4ZG76_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAX88939.1}; Flags: Fragment;+++[Q53TI5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TANK {ECO:0000313|EMBL:AAY14785.1}; Flags: Fragment;+++[Q6NW12_HUMAN|Unreviewed]SubName: Full=TANK protein {ECO:0000313|EMBL:AAH67779.1};"]
[100101267,"'POM121C'",1962.1,2840.04,2401.07,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005515///protein binding+++GO:0035804///structural constituent of egg coat+++GO:0017056///structural constituent of nuclear pore+++GO:0003676///nucleic acid binding+++GO:0008139///nuclear localization sequence binding","GO:0007339///binding of sperm to zona pellucida+++GO:0035803///egg coat formation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016032///viral process+++GO:0051028///mRNA transport+++GO:0006606///protein import into nucleus+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus","IPR026054///Nuclear pore complex protein+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR026090///Nuclear pore protein POM121","[P121C_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[A1L4L9_HUMAN|Unreviewed]SubName: Full=POM121C protein {ECO:0000313|EMBL:AAI30588.1};+++[A8MY32_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000381415}; Flags: Fragment;+++[B4DDR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56876, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG56826.1};+++[B4DET5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121 {ECO:0000313|EMBL:BAG57196.1};+++[C9JFL1_HUMAN|Unreviewed]SubName: Full=Nuclear envelope pore membrane protein POM 121C {ECO:0000313|Ensembl:ENSP00000410033}; Flags: Fragment;"]
[100101467,"'ZSCAN30'",119,120,119.5,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR003309///SCAN domain+++IPR038269///SCAN domain superfamily+++IPR036236///Zinc finger C2H2 superfamily","[ZSC30_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 30; AltName: Full=ZNF-WYM; AltName: Full=Zinc finger protein 397 opposite strand; AltName: Full=Zinc finger protein 397OS;+++[A0A0C4DGV0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000480152};+++[A0A1W2PP20_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000491237};+++[C9JCM2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000465046};+++[K7EPB0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000467308}; Flags: Fragment;+++[K7ERA9_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000468180}; Flags: Fragment;+++[M0QZC3_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470443};+++[M0QZP2_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000470677}; Flags: Fragment;+++[M0R1Y0_HUMAN|Unreviewed]SubName: Full=Zinc finger and SCAN domain-containing protein 30 {ECO:0000313|Ensembl:ENSP00000472179};"]
[10011,"'SRA1'",849,746,797.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge","GO:0003713///transcription coactivator activity+++GO:0002153///steroid receptor RNA activator RNA binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:2000273///positive regulation of signaling receptor activity+++GO:0008283///cell proliferation+++GO:0030154///cell differentiation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0006351///transcription, DNA-templated+++GO:0071391///cellular response to estrogen stimulus","IPR009917///Steroid receptor RNA activator-protein/coat protein complex II, Sec31","[SRA1_HUMAN|Reviewed]RecName: Full=Steroid receptor RNA activator 1; AltName: Full=Steroid receptor RNA activator protein; Short=SRAP;"]
[100113407,"'TMEM170B'",58.94,86.01,72.475,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway","IPR019334///Transmembrane protein 170","[T170B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 170B;"]
[100125288,"'ZGLP1'",49,35,42,{"$nulls":4},"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0048599///oocyte development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis","IPR013088///Zinc finger, NHR/GATA-type+++IPR000679///Zinc finger, GATA-type+++IPR039355///Transcription factor GATA","[ZGLP1_HUMAN|Reviewed]RecName: Full=GATA-type zinc finger protein 1; AltName: Full=GATA-like protein 1; Short=GLP-1;+++[B5MCP8_HUMAN|Unreviewed]SubName: Full=GATA-type zinc finger protein 1 {ECO:0000313|Ensembl:ENSP00000385403};"]
[100127983,"'C8orf88'",77,67,72,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0008190///eukaryotic initiation factor 4E binding","GO:0045947///negative regulation of translational initiation","IPR011992///EF-hand domain pair+++IPR018247///EF-Hand 1, calcium-binding site+++IPR007138///Antibiotic biosynthesis monooxygenase domain+++IPR011008///Dimeric alpha-beta barrel+++IPR002048///EF-hand domain","[CH088_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C8orf88;"]
[100128071,"'FAM229A'",23,17,20,{"$nulls":7},"IPR028025///FAM229 protein","[F229A_HUMAN|Reviewed]RecName: Full=Protein FAM229A;+++[H3BMD6_HUMAN|Unreviewed]SubName: Full=Protein FAM229A {ECO:0000313|Ensembl:ENSP00000454338}; Flags: Fragment;"]
[100128108,"'LOC100128108'",12,5,8.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",{"$nulls":3},"[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;+++[UB2Q2_BOVIN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_HUMAN|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_MOUSE|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-protein ligase Q2;+++[UB2Q2_RABIT|diamond]RecName: Full=Ubiquitin-conjugating enzyme E2 Q2; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Q2; AltName: Full=Ubiquitin carrier protein Q2; AltName: Full=Ubiquitin-conjugating enzyme UBCi; AltName: Full=Ubiquitin-protein ligase Q2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100128242,"'LOC100128242'",3,10,6.5,{"$nulls":8},"[A0A1B0GVV0_HUMAN|diamond]SubName: Full=GRAM domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000490665};+++[A0A2I3SSV7_PANTR|diamond]SubName: Full=GRAM domain containing 1B {ECO:0000313|Ensembl:ENSPTRP00000080022};+++[A0A2J8N1X4_PANTR|diamond]SubName: Full=GRAMD1B isoform 18 {ECO:0000313|EMBL:PNI65769.1};+++[A0A2J8X087_PONAB|diamond]SubName: Full=GRAMD1B isoform 17 {ECO:0000313|EMBL:PNJ75447.1};+++[A0A2R9B6E3_PANPA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPAP00000024636};"]
[100128553,"'CTAGE4'",86.35,66.9,76.625,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0042954///lipoprotein transporter activity","GO:0042953///lipoprotein transport+++GO:0008150///biological_process+++GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion",null,"[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[A0A2R8Y569_HUMAN|Unreviewed]SubName: Full=cTAGE family member 4 {ECO:0000313|Ensembl:ENSP00000494570};"]
[100128569,"'C19orf71'",2,0,1,{"$nulls":7},"IPR029203///Protein of unknown function DUF4531","[CS071_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf71;"]
[100128731,"'OST4'",1589,1584,1586.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0015631///tubulin binding+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding","GO:0018279///protein N-linked glycosylation via asparagine+++GO:0006486///protein glycosylation","IPR036330///Oligosaccharyltransferase subunit ost4p superfamily+++IPR018943///Oligosaccaryltransferase","[OST4_HUMAN|Reviewed]RecName: Full=Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4;"]
[100128927,"'ZBTB42'",61,61,61,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0007517///muscle organ development+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR000210///BTB/POZ domain+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR011333///SKP1/BTB/POZ domain superfamily","[ZBT42_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 42;"]
[100129128,"'KHDC1L'",0,1,0.5,{"$nulls":5},"GO:0003723///RNA binding",null,"IPR036612///K Homology domain, type 1 superfamily+++IPR031952///KH-like RNA-binding domain","[KHDCL_HUMAN|Reviewed]RecName: Full=Putative KHDC1-like protein;"]
[100129250,"'SMIM27'",47,35,41,"05016///Huntington's disease+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++05012///Parkinson's disease+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)",null,"M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly","IPR019174///NADH dehydrogenase 1, beta subcomplex, subunit 6","[SIM27_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 27 {ECO:0000305}; AltName: Full=TOPORS antisense RNA 1 {ECO:0000305};+++[A0A1B0GV65_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490387};+++[A0A1B0GW09_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000490727}; Flags: Fragment;+++[A0A1W2PRY6_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000492552}; Flags: Fragment;+++[A0A286YEC1_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000414891};+++[A0A2R8Y3B0_HUMAN|Unreviewed]SubName: Full=HCG1811779, isoform CRA_a {ECO:0000313|EMBL:EAW58544.1}; SubName: Full=Small integral membrane protein 27 {ECO:0000313|Ensembl:ENSP00000493510};"]
[100129271,"'C1orf68'",0,1,0.5,{"$nulls":4},"GO:0001533///cornified envelope+++GO:0005737///cytoplasm","GO:0005198///structural molecule activity+++GO:0003674///molecular_function","GO:0008544///epidermis development+++GO:0018149///peptide cross-linking+++GO:0030216///keratinocyte differentiation","IPR026075///Small proline-rich protein/late cornified envelope protein+++IPR026078///Skin-specific protein 32","[XP32_HUMAN|Reviewed]RecName: Full=Skin-specific protein 32;"]
[100129361,"'SMIM10L1'",537,457,497,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"IPR029367///Small integral membrane protein 10","[SIML1_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 10-like protein 1 {ECO:0000305};"]
[100129396,"'FAM106CP'",0,1,0.5,{"$nulls":8},"[F106C_HUMAN|Reviewed]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;"]
[100129480,"'MKRN2OS'",3.01,2.93,2.97,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR032016///Protein of unknown function DUF4796","[MKROS_HUMAN|Reviewed]RecName: Full=MKRN2 opposite strand protein; AltName: Full=MKRN2 antisense RNA 1; AltName: Full=MKRN2 antisense gene protein 1;+++[H3BSJ0_HUMAN|Unreviewed]SubName: Full=MKRN2 opposite strand protein {ECO:0000313|Ensembl:ENSP00000456723};"]
[100129484,"'LOC100129484'",14,16,15,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":7},"[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100129543,"'ZNF730'",2,7,4.5,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZN730_HUMAN|Reviewed]RecName: Full=Putative zinc finger protein 730;+++[M0QYG2_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469805}; Flags: Fragment;+++[M0QYI4_HUMAN|Unreviewed]SubName: Full=Putative zinc finger protein 730 {ECO:0000313|Ensembl:ENSP00000469853};"]
[100129583,"'FAM47E'",3.22,2.38,2.8,{"$nulls":4},"GO:0005737///cytoplasm","GO:0003674///molecular_function","GO:0008150///biological_process","IPR032743///FAM47 family","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[A0A1B0GTQ8_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000489801};+++[A0A1B0GUL4_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000490159};+++[D6RBT2_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000422559}; Flags: Fragment;+++[U3KQR7_HUMAN|Unreviewed]SubName: Full=Protein FAM47E {ECO:0000313|Ensembl:ENSP00000476166}; Flags: Fragment;"]
[100129792,"'CCDC152'",21,11,16,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031089///platelet dense granule lumen+++GO:0005576///extracellular region","GO:0008430///selenium binding","GO:0019953///sexual reproduction+++GO:0001887///selenium compound metabolic process+++GO:0007626///locomotory behavior+++GO:0002576///platelet degranulation+++GO:0009791///post-embryonic development+++GO:0006979///response to oxidative stress+++GO:0007420///brain development+++GO:0040008///regulation of growth","IPR038827///Coiled-coil domain-containing protein 152","[CC152_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 152;+++[A0A024R043_HUMAN|Unreviewed]SubName: Full=HCG2006161, isoform CRA_a {ECO:0000313|EMBL:EAW56025.1};+++[L0R835_HUMAN|Unreviewed]SubName: Full=Alternative protein CCDC152 {ECO:0000313|EMBL:CCO13701.1};"]
[100129842,"'ZNF737'",60.07,111,85.535,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box","[ZN737_HUMAN|Reviewed]RecName: Full=Zinc finger protein 737; AltName: Full=Zinc finger protein 102;+++[M0QZS4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000470737};+++[M0R1D1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471784}; Flags: Fragment;+++[M0R1M3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471973};+++[M0R1M8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 737 {ECO:0000313|Ensembl:ENSP00000471995}; Flags: Fragment;"]
[100129924,"'TMEM269'",3,3.7,3.35,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",{"$nulls":3},"[TM269_HUMAN|Reviewed]RecName: Full=Transmembrane protein 269 {ECO:0000312|HGNC:HGNC:52381};+++[A0A1B0GUR4_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 269 {ECO:0000313|Ensembl:ENSP00000490213};"]
[100129940,"'LOC100129940'",0,3,1.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030686///90S preribosome","GO:0043236///laminin binding+++GO:0043022///ribosome binding+++GO:0003723///RNA binding+++GO:0005055///laminin receptor activity+++GO:0001618///virus receptor activity+++GO:0003735///structural constituent of ribosome","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000028///ribosomal small subunit assembly+++GO:0007155///cell adhesion+++GO:0006412///translation+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006413///translational initiation+++GO:0000461///endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006407///rRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","IPR027498///Ribosomal protein S2, eukaryotic+++IPR032281///40S ribosomal protein SA, C-terminal domain+++IPR027504///40S ribosomal protein SA+++IPR005707///Ribosomal protein S2, eukaryotic/archaeal+++IPR001865///Ribosomal protein S2+++IPR018130///Ribosomal protein S2, conserved site+++IPR023591///Ribosomal protein S2, flavodoxin-like domain superfamily","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RSSA_BOVIN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Protein C10;+++[RSSA_CHLAE|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_HUMAN|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Colon carcinoma laminin-binding protein; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Multidrug resistance-associated protein MGr1-Ag; AltName: Full=NEM/1CHD4; AltName: Full=Small ribosomal subunit protein uS2 {ECO:0000303|PubMed:24524803};+++[RSSA_PIG|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[RSSA_SHEEP|diamond]RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016};+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10013,"'HDAC6'",676,703,689.5,"05034///Alcoholism+++05203///Viral carcinogenesis+++05165///Human papillomavirus infection",{"$nulls":3},"GO:0016235///aggresome+++GO:0005874///microtubule+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm+++GO:0016234///inclusion body+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0030286///dynein complex+++GO:0005654///nucleoplasm+++GO:0005771///multivesicular body+++GO:0031252///cell leading edge+++GO:0005875///microtubule associated complex+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005881///cytoplasmic microtubule+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005901///caveola+++GO:0044297///cell body+++GO:0043204///perikaryon+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0019899///enzyme binding+++GO:0008013///beta-catenin binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0048156///tau protein binding+++GO:0043130///ubiquitin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004407///histone deacetylase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0070840///dynein complex binding+++GO:0003779///actin binding+++GO:0042903///tubulin deacetylase activity+++GO:0051787///misfolded protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0051879///Hsp90 protein binding+++GO:0042826///histone deacetylase binding+++GO:0048487///beta-tubulin binding+++GO:0008017///microtubule binding+++GO:0043014///alpha-tubulin binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)","GO:0006886///intracellular protein transport+++GO:0031647///regulation of protein stability+++GO:0060997///dendritic spine morphogenesis+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0048668///collateral sprouting+++GO:0051788///response to misfolded protein+++GO:0070848///response to growth factor+++GO:0032984///protein-containing complex disassembly+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0009967///positive regulation of signal transduction+++GO:0000209///protein polyubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0035967///cellular response to topologically incorrect protein+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0051646///mitochondrion localization+++GO:0060271///cilium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0032461///positive regulation of protein oligomerization+++GO:0045861///negative regulation of proteolysis+++GO:0045598///regulation of fat cell differentiation+++GO:0040029///regulation of gene expression, epigenetic+++GO:0070846///Hsp90 deacetylation+++GO:0009636///response to toxic substance+++GO:0006325///chromatin organization+++GO:0032418///lysosome localization+++GO:0010033///response to organic substance+++GO:0010727///negative regulation of hydrogen peroxide metabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016241///regulation of macroautophagy+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006914///autophagy+++GO:0043242///negative regulation of protein complex disassembly+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1901300///positive regulation of hydrogen peroxide-mediated programmed cell death+++GO:0090042///tubulin deacetylation+++GO:0010506///regulation of autophagy+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0060632///regulation of microtubule-based movement+++GO:0006476///protein deacetylation+++GO:0070201///regulation of establishment of protein localization+++GO:0070842///aggresome assembly+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070845///polyubiquitinated misfolded protein transport+++GO:0010469///regulation of signaling receptor activity+++GO:0070932///histone H3 deacetylation+++GO:0016575///histone deacetylation+++GO:0010634///positive regulation of epithelial cell migration+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0060765///regulation of androgen receptor signaling pathway","IPR001607///Zinc finger, UBP-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR023696///Ureohydrolase domain superfamily+++IPR023801///Histone deacetylase domain+++IPR000286///Histone deacetylase family+++IPR037138///Histone deacetylase domain superfamily","[HDAC6_HUMAN|Reviewed]RecName: Full=Histone deacetylase 6; Short=HD6; EC=3.5.1.98;+++[A0A024QZ26_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8Y4G2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494007}; Flags: Fragment;+++[A0A2R8Y559_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494293}; Flags: Fragment;+++[A0A2R8Y5Z4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495151};+++[A0A2R8Y6Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495932}; Flags: Fragment;+++[A0A2R8Y758_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000496032}; Flags: Fragment;+++[A0A2R8YCS4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000493921}; Flags: Fragment;+++[A0A2R8YD35_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000494230}; Flags: Fragment;+++[A0A2R8YDE6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[A0A2R8YGC5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000495872}; Flags: Fragment;+++[A6NDI8_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000365831}; Flags: Fragment;+++[B4DZH6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};+++[C9J172_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000392815}; Flags: Fragment;+++[C9JEF4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000403370}; Flags: Fragment;+++[E7EP63_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402751}; Flags: Fragment;+++[E7EPS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000402189}; Flags: Fragment;+++[E7ER52_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000394377}; Flags: Fragment;+++[H7C0Z9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 6 {ECO:0000313|Ensembl:ENSP00000397697}; Flags: Fragment;+++[Q9BRX7_HUMAN|Unreviewed]SubName: Full=HDAC6 protein {ECO:0000313|EMBL:AAH05872.1}; SubName: Full=Histone deacetylase 6 {ECO:0000313|EMBL:AAP35295.1, ECO:0000313|Ensembl:ENSP00000393916};+++[Q9NSW6_HUMAN|Unreviewed]RecName: Full=Histone deacetylase {ECO:0000256|SAAS:SAAS00894283}; EC=3.5.1.98 {ECO:0000256|SAAS:SAAS00894283};"]
[100130086,"'HSFX2'",2.84,5.59,4.215,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding","GO:0006351///transcription, DNA-templated","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR037032///Heat shock transcription factor, X-linked+++IPR027725///Heat shock transcription factor family+++IPR000232///Heat shock factor (HSF)-type, DNA-binding","[HSFX1_HUMAN|Reviewed]RecName: Full=Heat shock transcription factor, X-linked;+++[A0A140VK21_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 21 {ECO:0000313|EMBL:AEE61158.1};"]
[100130311,"'C17orf107'",55,62,58.5,"04080///Neuroactive ligand-receptor interaction","H00770///Congenital myasthenic syndrome",{"$nulls":5},"IPR038963///Uncharacterized protein C17orf107","[CQ107_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C17orf107;+++[E5RJ01_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C17orf107 {ECO:0000313|Ensembl:ENSP00000429241};"]
[100130357,"'LOC100130357'",3,4,3.5,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[RABX5_HUMAN|diamond]RecName: Full=Rab5 GDP/GTP exchange factor; AltName: Full=RAP1; AltName: Full=Rabaptin-5-associated exchange factor for Rab5; AltName: Full=Rabex-5;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[100130361,"'CXorf49'",3.5,2,2.75,{"$nulls":7},"IPR027822///Protein of unknown function DUF4641","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100130370,"'LOC100130370'",38,74,56,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":7},"[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CN178_HUMAN|diamond]RecName: Full=Uncharacterized protein C14orf178;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100130451,"'LOC100130451'",6,3,4.5,{"$nulls":8},"[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[100130519,"'TMEM221'",37,27,32,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IPR029201///Jiraiya","[TM221_HUMAN|Reviewed]RecName: Full=Transmembrane protein 221;"]
[100130520,"'CD300H'",0,1,0.5,{"$nulls":4},"GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0001816///cytokine production+++GO:0030593///neutrophil chemotaxis","IPR007110///Immunoglobulin-like domain+++IPR003599///Immunoglobulin subtype+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013106///Immunoglobulin V-set domain+++IPR013783///Immunoglobulin-like fold","[A0A0K2S4Q6_HUMAN|Unreviewed]SubName: Full=CD300H {ECO:0000313|EMBL:BAS22088.1};+++[A0A0K2S5L2_HUMAN|Unreviewed]SubName: Full=CD300Hs {ECO:0000313|EMBL:BAS22089.1};+++[A0A286YF48_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000492997};"]
[100130705,"'ATP6V1FNB'",42,25,33.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR019351///Protein of unknown function DUF2039","[VAFNB_HUMAN|Reviewed]RecName: Full=Protein ATP6V1FNB {ECO:0000305}; AltName: Full=ATP6V1F neighbor gene protein {ECO:0000305};"]
[100130771,"'EFCAB10'",1,5,3,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0010494///cytoplasmic stress granule+++GO:0005576///extracellular region+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0070939///Dsl1/NZR complex+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0005509///calcium ion binding","GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0006397///mRNA processing+++GO:0015031///protein transport+++GO:0006351///transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0051781///positive regulation of cell division+++GO:1902504///regulation of signal transduction involved in mitotic G2 DNA damage checkpoint+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007049///cell cycle+++GO:0006355///regulation of transcription, DNA-templated","IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain+++IPR039879///EF-hand calcium-binding domain-containing protein 10","[EFC10_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 10;+++[A0A2R8Y6P2_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000495682};+++[A0A2R8YDC4_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000494437};+++[C9J654_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000418425};+++[J3KR48_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417484}; SubName: Full=HCG1779729, isoform CRA_a {ECO:0000313|EMBL:EAW83368.1};+++[J3KR52_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000417841};"]
[100130890,"'TSTD3'",67.33,60,63.665,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016592///mediator complex+++GO:0005829///cytosol+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0070911///global genome nucleotide-excision repair+++GO:0016579///protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1901409///positive regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:0006281///DNA repair+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR001763///Rhodanese-like domain+++IPR036873///Rhodanese-like domain superfamily","[TSTD3_HUMAN|Reviewed]RecName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3; AltName: Full=Rhodanese domain-containing protein 3;+++[A0A1B0GUB9_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000490043};"]
[100130958,"'SYCE1L'",16,19,17.5,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04138///Autophagy - yeast",{"$nulls":3},"GO:0000795///synaptonemal complex+++GO:0045111///intermediate filament cytoskeleton",null,"GO:0051321///meiotic cell cycle+++GO:0070193///synaptonemal complex organization+++GO:0007130///synaptonemal complex assembly","IPR026676///Synaptonemal complex central element protein 1","[SYC1L_HUMAN|Reviewed]RecName: Full=Synaptonemal complex central element protein 1-like; AltName: Full=Meiosis-related protein;+++[H3BME6_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex central element protein 1-like {ECO:0000313|Ensembl:ENSP00000454349}; Flags: Fragment;"]
[100130967,"'C6orf99'",29,15,22,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":7},"[CF099_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C6orf99;"]
[100131017,"'ZNF316'",558,659,608.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN316_HUMAN|Reviewed]RecName: Full=Zinc finger protein 316;+++[A0A087WZ61_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 316 {ECO:0000313|Ensembl:ENSP00000482395}; Flags: Fragment;"]
[100131187,"'TSTD1'",128,95,111.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005615///extracellular space+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005739///mitochondrion","GO:0008097///5S rRNA binding+++GO:0004792///thiosulfate sulfurtransferase activity+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0050337///thiosulfate-thiol sulfurtransferase activity","GO:0051029///rRNA transport+++GO:0030855///epithelial cell differentiation+++GO:0070221///sulfide oxidation, using sulfide:quinone oxidoreductase+++GO:0035928///rRNA import into mitochondrion+++GO:0000098///sulfur amino acid catabolic process+++GO:0009440///cyanate catabolic process","IPR036873///Rhodanese-like domain superfamily+++IPR001763///Rhodanese-like domain","[TSTD1_HUMAN|Reviewed]RecName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000303|PubMed:24981631}; Short=TST {ECO:0000303|PubMed:24981631}; EC=2.8.1.- {ECO:0000269|PubMed:24981631};+++[B1AH48_HUMAN|Unreviewed]SubName: Full=Thiosulfate sulfurtransferase {ECO:0000313|Ensembl:ENSP00000400764}; Flags: Fragment;+++[R4GNF9_HUMAN|Unreviewed]SubName: Full=Thiosulfate:glutathione sulfurtransferase {ECO:0000313|Ensembl:ENSP00000473633};"]
[100131211,"'NEMP2'",6,1,3.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005635///nuclear envelope","GO:0003964///RNA-directed DNA polymerase activity",null,"IPR019358///NEMP family","[NEMP2_HUMAN|Reviewed]RecName: Full=Nuclear envelope integral membrane protein 2; Flags: Precursor;+++[C9J4F2_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000410306}; Flags: Fragment;+++[F8VWJ7_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000340087};+++[H7C232_HUMAN|Unreviewed]SubName: Full=Nuclear envelope integral membrane protein 2 {ECO:0000313|Ensembl:ENSP00000403867}; Flags: Fragment;"]
[100131378,"'C11orf91'",3,2,2.5,{"$nulls":7},"IPR040027///Uncharacterized protein C11orf91-like","[CK091_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf91;+++[H0YDE1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C11orf91 {ECO:0000313|Ensembl:ENSP00000433460}; Flags: Fragment;"]
[100131390,"'SP9'",2,0,1,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0030326///embryonic limb morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[SP9_HUMAN|Reviewed]RecName: Full=Transcription factor Sp9;"]
[100131608,"'PRR23D1'",0,0.06,0.03,{"$nulls":7},"IPR018903///Proline-rich protein 23","[P23D1_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D1;+++[P23D2_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D2;"]
[100131755,"'ARMCX4'",46,48,47,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0016018///cyclosporin A binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0046790///virion binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding+++GO:0051082///unfolded protein binding","GO:0048469///cell maturation+++GO:0071226///cellular response to molecule of fungal origin+++GO:0035556///intracellular signal transduction+++GO:0019064///fusion of virus membrane with host plasma membrane+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0019061///uncoating of virus+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0098761///cellular response to interleukin-7+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0034389///lipid droplet organization+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0002721///regulation of B cell cytokine production+++GO:0019076///viral release from host cell+++GO:0006351///transcription, DNA-templated+++GO:0045579///positive regulation of B cell differentiation+++GO:0042127///regulation of cell proliferation+++GO:0002553///histamine secretion by mast cell+++GO:0097190///apoptotic signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0006310///DNA recombination+++GO:0075713///establishment of integrated proviral latency+++GO:0045087///innate immune response+++GO:0002344///B cell affinity maturation+++GO:0050853///B cell receptor signaling pathway+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0030260///entry into host cell+++GO:0019722///calcium-mediated signaling+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0002250///adaptive immune response+++GO:0034614///cellular response to reactive oxygen species+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0030889///negative regulation of B cell proliferation+++GO:0050900///leukocyte migration+++GO:0019058///viral life cycle+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0007498///mesoderm development+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0019068///virion assembly+++GO:0042113///B cell activation+++GO:0045069///regulation of viral genome replication+++GO:0002902///regulation of B cell apoptotic process+++GO:0006278///RNA-dependent DNA biosynthetic process+++GO:0001818///negative regulation of cytokine production+++GO:0006468///protein phosphorylation+++GO:0032197///transposition, RNA-mediated","IPR000225///Armadillo+++IPR006911///Armadillo repeat-containing domain+++IPR016024///Armadillo-type fold","[ARMX4_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 4;+++[A0A024RCH4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 4, isoform CRA_b {ECO:0000313|EMBL:EAX02871.1};+++[D6RBS8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000422573};+++[F8W8Y7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 4 {ECO:0000313|Ensembl:ENSP00000404304};+++[L8EAW9_HUMAN|Unreviewed]SubName: Full=Alternative protein ARMCX4 {ECO:0000313|EMBL:CCQ43981.1};"]
[100131801,"'PET100'",206,162,184,"03040///Spliceosome","H01368///Cytochrome c oxidase (COX) deficiency","M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0051082///unfolded protein binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","IPR018625///Protein Pet100","[PT100_HUMAN|Reviewed]RecName: Full=Protein PET100 homolog, mitochondrial; Flags: Precursor;+++[A0A0A0MSK2_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000392303};+++[M0QZ55_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470314}; Flags: Fragment;+++[M0R022_HUMAN|Unreviewed]SubName: Full=Protein PET100 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000470935};"]
[100131827,"'ZNF717'",40,26,33,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily","[ZN717_HUMAN|Reviewed]RecName: Full=Zinc finger protein 717; AltName: Full=Krueppel-like factor X17;+++[C9J5W8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000417902};+++[C9J8I7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000418187}; Flags: Fragment;+++[C9JVC3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000419377};+++[E5RKB3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 717 {ECO:0000313|Ensembl:ENSP00000420241}; Flags: Fragment;"]
[100131897,"'INSYN2B'",140,121,130.5,"04062///Chemokine signaling pathway+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0035580///specific granule lumen+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0042608///T cell receptor binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0050766///positive regulation of phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0001766///membrane raft polarization+++GO:0045059///positive thymic T cell selection+++GO:0044351///macropinocytosis+++GO:0045060///negative thymic T cell selection+++GO:0002277///myeloid dendritic cell activation involved in immune response+++GO:0006935///chemotaxis+++GO:0050690///regulation of defense response to virus by virus+++GO:0001771///immunological synapse formation+++GO:0007264///small GTPase mediated signal transduction+++GO:0001768///establishment of T cell polarity+++GO:0046633///alpha-beta T cell proliferation","IPR029337///Inhibitory synaptic factor 2","[INY2B_HUMAN|Reviewed]RecName: Full=Protein INSYN2B {ECO:0000305}; AltName: Full=Inhibitory synaptic factor family member 2B {ECO:0000312|HGNC:HGNC:37271};"]
[100132015,"'TEX13D'",0,4,2,{"$nulls":5},"GO:0046872///metal ion binding",null,"IPR001876///Zinc finger, RanBP2-type+++IPR028193///Testis-expressed sequence 13 protein family","[TX13D_HUMAN|Reviewed]RecName: Full=Testis-expressed protein 13D {ECO:0000305};"]
[100132074,"'FOXO6'",68,54,61,"04068///FoxO signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0042593///glucose homeostasis+++GO:0008286///insulin receptor signaling pathway+++GO:0007613///memory+++GO:0060999///positive regulation of dendritic spine development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR032067///FOXO protein, transactivation domain+++IPR032068///FOXO protein, KIX-binding domain+++IPR001766///Fork head domain+++IPR030456///Fork head domain conserved site 2","[FOXO6_HUMAN|Reviewed]RecName: Full=Forkhead box protein O6;+++[A0A1X9RU27_HUMAN|Unreviewed]SubName: Full=Forkhead box protein O6 {ECO:0000313|EMBL:ARQ84049.1};"]
[100132247,"'NPIPB5'",1916.81,2324.96,2120.885,"00650///Butanoate metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++01100///Metabolic pathways",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane",null,null,"IPR009443///Nuclear pore complex interacting protein","[NPIB5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B5;+++[B4E0Y1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61599 {ECO:0000313|EMBL:BAG64593.1};+++[E5RHP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000456511}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000429523}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000428548}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449726};+++[E7EUG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000392155};+++[E9PKP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000431553}; Flags: Fragment;+++[F5GWQ4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B13 {ECO:0000313|Ensembl:ENSP00000457242}; SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000442776}; SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441759}; SubName: Full=Nuclear pore complex-interacting protein family, member B12 {ECO:0000313|Ensembl:ENSP00000449771};+++[F5GXZ6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000440137}; Flags: Fragment;+++[F5GYP3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000441303}; Flags: Fragment;+++[F5GZP9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000444299}; Flags: Fragment;+++[F5H6Y6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442935}; Flags: Fragment;+++[F6SDX0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000445388}; Flags: Fragment;+++[H0YIL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000449628}; Flags: Fragment;+++[U3KRG3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B5 {ECO:0000313|Ensembl:ENSP00000442912}; Flags: Fragment;"]
[100132386,"'KRTAP4-9'",1,1,1,{"$nulls":4},"GO:0005882///intermediate filament+++GO:0005829///cytosol+++GO:0045095///keratin filament",null,"GO:0031424///keratinization+++GO:0042633///hair cycle+++GO:0007568///aging","IPR002494///Keratin-associated protein","[KRA49_HUMAN|Reviewed]RecName: Full=Keratin-associated protein 4-9; AltName: Full=Keratin-associated protein 4.9; AltName: Full=Ultrahigh sulfur keratin-associated protein 4.9;+++[A0A087X0S9_HUMAN|Unreviewed]SubName: Full=Keratin-associated protein 4-9 {ECO:0000313|Ensembl:ENSP00000483635};+++[A0A0G2JLF9_HUMAN|Unreviewed]SubName: Full=HCG2043351 {ECO:0000313|EMBL:EAW60707.1}; SubName: Full=Keratin-associated protein 4-9 {ECO:0000313|Ensembl:ENSP00000461444};"]
[100132406,"'NBPF10'",129.57,259.1,194.335,"01522///Endocrine resistance+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++04140///Autophagy - animal+++05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation+++04137///Mitophagy - animal+++05224///Breast cancer","H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0003723///RNA binding","GO:0007275///multicellular organism development+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway","IPR010630///Neuroblastoma breakpoint family (NBPF) domain","[NBPFA_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 10;+++[A0A075B762_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000463957};+++[A0A087WVC7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|Ensembl:ENSP00000479344};+++[A0A087WVG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000479415};+++[A0A087WYQ9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482016};+++[A0A087WZE1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000482587};+++[A0A087X0Y3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 9 {ECO:0000313|Ensembl:ENSP00000483736};+++[A2BH96_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 10 {ECO:0000313|EMBL:CAM23768.1};+++[I0CMK7_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFH78588.1}; Flags: Fragment;+++[I1VE12_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41822.1}; Flags: Fragment;+++[I1VE13_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41823.1}; Flags: Fragment;+++[I1VE14_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 10 {ECO:0000313|EMBL:AFI41824.1}; Flags: Fragment;+++[L8E7E2_HUMAN|Unreviewed]SubName: Full=Alternative protein NBPF9 {ECO:0000313|EMBL:CCQ43049.1};+++[Q5TB04_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family, member 9 {ECO:0000313|EMBL:CAI22821.1}; Flags: Fragment;"]
[100132565,"'GOLGA8F'",0,3,1.5,"04120///Ubiquitin mediated proteolysis","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005794///Golgi apparatus","GO:0004842///ubiquitin-protein transferase activity+++GO:0032183///SUMO binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006886///intracellular protein transport+++GO:0007283///spermatogenesis+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0016567///protein ubiquitination","IPR024858///Golgin subfamily A","[A0A0G2JP71_HUMAN|Unreviewed]SubName: Full=Putative golgin subfamily A member 8F/8G {ECO:0000313|Ensembl:ENSP00000483042};+++[A0A0G2JPF6_HUMAN|Unreviewed]SubName: Full=Putative golgin subfamily A member 8F/8G {ECO:0000313|Ensembl:ENSP00000483530};"]
[100132813,"'LOC100132813'",0,1,0.5,{"$nulls":8},"[A0A0D9RFT1_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000007470};+++[A0A2K5ELV0_AOTNA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSANAP00000034188};+++[A0A2K5HE23_COLAP|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCANP00000002593};+++[A0A2K6TW16_SAIBB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSBOP00000023852};+++[I7GCC4_MACFA|diamond]SubName: Full=Macaca fascicularis brain cDNA, clone: QflA-18945 {ECO:0000313|EMBL:BAE89674.1};"]
[100132874,"'LOC100132874'",0,1,0.5,{"$nulls":8},"[RRBP1_MOUSE|diamond]RecName: Full=Ribosome-binding protein 1; AltName: Full=Ribosome receptor protein; Short=RRp; Short=mRRp;+++[SRFB1_XENTR|diamond]RecName: Full=Serum response factor-binding protein 1; AltName: Full=SRF-dependent transcription regulation-associated protein;"]
[100132911,"'DPH3P1'",1.04,2,1.52,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046872///metal ion binding","GO:0017183///peptidyl-diphthamide biosynthetic process from peptidyl-histidine+++GO:0002098///tRNA wobble uridine modification","IPR036671///DPH Zinc finger superfamily+++IPR007872///Zinc finger, DPH-type","[DPH3B_HUMAN|Reviewed]RecName: Full=Putative DPH3 homolog B; AltName: Full=CSL-type zinc finger-containing protein 1;"]
[100132994,"'CXorf49B'",3.5,2,2.75,{"$nulls":7},"IPR027822///Protein of unknown function DUF4641","[CX049_HUMAN|Reviewed]RecName: Full=Uncharacterized protein CXorf49 {ECO:0000305};"]
[100133093,"'FAM25G'",1,0,0.5,{"$nulls":7},"IPR023243///FAM25","[FM25A_HUMAN|Reviewed]RecName: Full=Protein FAM25A {ECO:0000305};+++[FM25C_HUMAN|Reviewed]RecName: Full=Protein FAM25C {ECO:0000305};+++[FM25G_HUMAN|Reviewed]RecName: Full=Protein FAM25G {ECO:0000305};+++[B7ZW47_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 25, member C {ECO:0000313|EMBL:AAI71871.1};"]
[100133204,"'C9orf147'",3,3,3,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005777///peroxisome+++GO:0016020///membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0051213///dioxygenase activity","GO:0010468///regulation of gene expression","IPR036291///NAD(P)-binding domain superfamily+++IPR002347///Short-chain dehydrogenase/reductase SDR+++IPR020904///Short-chain dehydrogenase/reductase, conserved site+++IPR019734///Tetratricopeptide repeat+++IPR003033///SCP2 sterol-binding domain+++IPR019351///Protein of unknown function DUF2039+++IPR036527///SCP2 sterol-binding domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR029516///Histone demethylase UTY+++IPR011990///Tetratricopeptide-like helical domain superfamily","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[HSDL2_BOVIN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_HUMAN|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-; AltName: Full=Short chain dehydrogenase/reductase family 13C member 1;+++[HSDL2_PONAB|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENLA|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[HSDL2_XENTR|diamond]RecName: Full=Hydroxysteroid dehydrogenase-like protein 2; EC=1.-.-.-;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100133220,"'GOLGA6L3'",1.79,0,0.895,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"IPR024858///Golgin subfamily A+++IPR026737///Golgin subfamily A member 6-like","[GG6L3_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 3;"]
[100133251,"'PRR23D2'",0,1.94,0.97,{"$nulls":7},"IPR018903///Proline-rich protein 23","[P23D1_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D1;+++[P23D2_HUMAN|Reviewed]RecName: Full=Proline-rich protein 23D2;"]
[100133941,"'CD24'",2700,2298.55,2499.275,"04640///Hematopoietic cell lineage",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0031362///anchored component of external side of plasma membrane+++GO:0045121///membrane raft+++GO:0009986///cell surface+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030296///protein tyrosine kinase activator activity","GO:0032597///B cell receptor transport into membrane raft+++GO:0032913///negative regulation of transforming growth factor beta3 production+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0030856///regulation of epithelial cell differentiation+++GO:0045730///respiratory burst+++GO:0043406///positive regulation of MAP kinase activity+++GO:0016055///Wnt signaling pathway+++GO:0007155///cell adhesion+++GO:0016477///cell migration+++GO:2000768///positive regulation of nephron tubule epithelial cell differentiation+++GO:0001775///cell activation+++GO:0042632///cholesterol homeostasis+++GO:0002237///response to molecule of bacterial origin+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072139///glomerular parietal epithelial cell differentiation+++GO:0001666///response to hypoxia+++GO:0042325///regulation of phosphorylation+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0032600///chemokine receptor transport out of membrane raft+++GO:0043408///regulation of MAPK cascade+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0031295///T cell costimulation+++GO:0043627///response to estrogen+++GO:0001959///regulation of cytokine-mediated signaling pathway+++GO:0002768///immune response-regulating cell surface receptor signaling pathway+++GO:0098609///cell-cell adhesion","IPR028029///Signal transducer CD24","[CD24_HUMAN|Reviewed]RecName: Full=Signal transducer CD24; AltName: Full=Small cell lung carcinoma cluster 4 antigen; AltName: CD_antigen=CD24; Flags: Precursor;+++[A0A087WU21_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478302};+++[A0A087WU87_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000478460}; Flags: Fragment;+++[A0A087WW33_HUMAN|Unreviewed]SubName: Full=Signal transducer CD24 {ECO:0000313|Ensembl:ENSP00000479895}; Flags: Fragment;"]
[100134444,"'KCNJ18'",2,0,1,"04725///Cholinergic synapse+++04921///Oxytocin signaling pathway","H00747///Thyrotoxic hypokalemic periodic paralysis (TPP)",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005244///voltage-gated ion channel activity+++GO:0005242///inward rectifier potassium channel activity","GO:0006811///ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0006813///potassium ion transport+++GO:1990573///potassium ion import across plasma membrane","IPR013518///Potassium channel, inwardly rectifying, Kir, cytoplasmic+++IPR014756///Immunoglobulin E-set+++IPR013673///Potassium channel, inwardly rectifying, Kir, N-terminal+++IPR016449///Potassium channel, inwardly rectifying, Kir+++IPR003272///Potassium channel, inwardly rectifying, Kir2.2","[KCJ18_HUMAN|Reviewed]RecName: Full=Inward rectifier potassium channel 18; AltName: Full=Inward rectifier K(+) channel Kir2.6; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 18;"]
[100134934,"'TEN1'",212,141,176.5,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0005634///nucleus+++GO:0000781///chromosome, telomeric region+++GO:1990879///CST complex+++GO:0005694///chromosome","GO:0042162///telomeric DNA binding+++GO:0005515///protein binding+++GO:0010521///telomerase inhibitor activity+++GO:0003697///single-stranded DNA binding+++GO:0003677///DNA binding","GO:0016233///telomere capping+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0051974///negative regulation of telomerase activity","IPR029146///CST complex subunit Ten1, animal and plant type","[TEN1L_HUMAN|Reviewed]RecName: Full=CST complex subunit TEN1; AltName: Full=Protein telomeric pathways with STN1 homolog; AltName: Full=Telomere length regulation protein TEN1 homolog;+++[D3U720_HUMAN|Unreviewed]SubName: Full=Telomeric pathways in association with Stn1 number 1 {ECO:0000313|EMBL:ACY71128.1};+++[K7EIL0_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000464792}; Flags: Fragment;+++[K7EJS2_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465299}; Flags: Fragment;+++[K7EL09_HUMAN|Unreviewed]SubName: Full=CST complex subunit TEN1 {ECO:0000313|Ensembl:ENSP00000465866};"]
[100134938,"'UPK3BL1'",334.35,300.63,317.49,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR024831///Uroplakin-3+++IPR024827///Uroplakin-3b-like 1/2","[UPK3L_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 1 {ECO:0000312|HGNC:HGNC:37278}; Flags: Precursor;+++[UPKL2_HUMAN|Reviewed]RecName: Full=Uroplakin-3b-like protein 2 {ECO:0000305}; Flags: Precursor;"]
[100137047,"'JMJD7'",42.56,50.36,46.46,{"$nulls":5},"GO:0005515///protein binding",null,"IPR003347///JmjC domain","[JMJD7_HUMAN|Reviewed]RecName: Full=JmjC domain-containing protein 7; AltName: Full=Jumonji domain-containing protein 7;+++[B5MC20_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000384174};+++[C9K0I3_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 7 {ECO:0000313|Ensembl:ENSP00000399600}; Flags: Fragment;"]
[10014,"'HDAC5'",475,455,465,"04371///Apelin signaling pathway+++05165///Human papillomavirus infection+++05169///Epstein-Barr virus infection+++05034///Alcoholism+++05203///Viral carcinogenesis","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0005829///cytosol+++GO:0000118///histone deacetylase complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0008134///transcription factor binding+++GO:0003682///chromatin binding+++GO:0042826///histone deacetylase binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0070491///repressing transcription factor binding+++GO:0005515///protein binding+++GO:0005080///protein kinase C binding+++GO:0033558///protein deacetylase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0030183///B cell differentiation+++GO:0010830///regulation of myotube differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006954///inflammatory response+++GO:0042113///B cell activation+++GO:0014823///response to activity+++GO:0010832///negative regulation of myotube differentiation+++GO:0042493///response to drug+++GO:0043393///regulation of protein binding+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042220///response to cocaine+++GO:0040029///regulation of gene expression, epigenetic+++GO:0030182///neuron differentiation+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0006338///chromatin remodeling+++GO:0070932///histone H3 deacetylation+++GO:0006476///protein deacetylation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006325///chromatin organization+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0006342///chromatin silencing+++GO:0016575///histone deacetylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032869///cellular response to insulin stimulus","IPR037138///Histone deacetylase domain superfamily+++IPR023801///Histone deacetylase domain+++IPR030703///Histone deacetylase 5+++IPR000286///Histone deacetylase family+++IPR017320///Histone deacetylase class II, eukaryotic+++IPR024643///Histone deacetylase, glutamine rich N-terminal domain+++IPR023696///Ureohydrolase domain superfamily","[HDAC5_HUMAN|Reviewed]RecName: Full=Histone deacetylase 5; Short=HD5; EC=3.5.1.98; AltName: Full=Antigen NY-CO-9;+++[K7EJL4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465227}; Flags: Fragment;+++[K7EJL6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465229}; Flags: Fragment;+++[K7EJZ7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000465393}; Flags: Fragment;+++[K7ES01_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 5 {ECO:0000313|Ensembl:ENSP00000468485}; Flags: Fragment;"]
[100142659,"'CTAGE8'",9.62,50.19,29.905,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0042954///lipoprotein transporter activity","GO:0035459///cargo loading into vesicle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0009306///protein secretion+++GO:0042953///lipoprotein transport",null,"[CTGE4_HUMAN|Reviewed]RecName: Full=cTAGE family member 4; Short=Protein cTAGE-4;+++[CTGE8_HUMAN|Reviewed]RecName: Full=cTAGE family member 8; Short=Protein cTAGE-8;"]
[100144595,"'LOC100144595'",0,1,0.5,{"$nulls":7},"IPR019351///Protein of unknown function DUF2039","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100144748,"'KLLN'",29,43,36,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003677///DNA binding","GO:0006915///apoptotic process+++GO:0007050///cell cycle arrest+++GO:0007049///cell cycle",null,"[KILIN_HUMAN|Reviewed]RecName: Full=Killin;"]
[10015,"'PDCD6IP'",2407,2548,2477.5,"04144///Endocytosis",{"$nulls":3},"GO:0001772///immunological synapse+++GO:0005923///bicellular tight junction+++GO:0042470///melanosome+++GO:0070971///endoplasmic reticulum exit site+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:1903561///extracellular vesicle+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0042641///actomyosin+++GO:0005815///microtubule organizing center+++GO:0005925///focal adhesion+++GO:0090543///Flemming body","GO:0048306///calcium-dependent protein binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0031871///proteinase activated receptor binding","GO:1903543///positive regulation of exosomal secretion+++GO:0070830///bicellular tight junction assembly+++GO:0007080///mitotic metaphase plate congression+++GO:0090611///ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway+++GO:0019058///viral life cycle+++GO:0016032///viral process+++GO:0046755///viral budding+++GO:1903551///regulation of extracellular exosome assembly+++GO:0015031///protein transport+++GO:0006997///nucleus organization+++GO:0000281///mitotic cytokinesis+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0007049///cell cycle+++GO:1901673///regulation of mitotic spindle assembly+++GO:0000915///actomyosin contractile ring assembly+++GO:0039702///viral budding via host ESCRT complex+++GO:0051260///protein homooligomerization+++GO:0010824///regulation of centrosome duplication+++GO:0036258///multivesicular body assembly+++GO:1903553///positive regulation of extracellular exosome assembly+++GO:0006915///apoptotic process+++GO:0090559///regulation of membrane permeability+++GO:0061952///midbody abscission+++GO:0051301///cell division","IPR004328///BRO1 domain+++IPR038499///BRO1 domain superfamily+++IPR025304///ALIX V-shaped domain","[PDC6I_HUMAN|Reviewed]RecName: Full=Programmed cell death 6-interacting protein; Short=PDCD6-interacting protein; AltName: Full=ALG-2-interacting protein 1; AltName: Full=ALG-2-interacting protein X; AltName: Full=Hp95;+++[C9IZF9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000406693}; Flags: Fragment;+++[F8WBR8_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000398895};+++[F8WDK9_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000415150};+++[F8WEQ7_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6-interacting protein {ECO:0000313|Ensembl:ENSP00000393777};+++[Q4W4Y1_HUMAN|Unreviewed]SubName: Full=Dopamine receptor interacting protein 4 {ECO:0000313|EMBL:AAQ14260.1};"]
[10016,"'PDCD6'",641,417,529,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030127///COPII vesicle coat+++GO:0070062///extracellular exosome+++GO:0005768///endosome+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0015629///actin cytoskeleton+++GO:0048471///perinuclear region of cytoplasm+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0060090///molecular adaptor activity+++GO:0005509///calcium ion binding+++GO:0046982///protein heterodimerization activity+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0042802///identical protein binding+++GO:0048306///calcium-dependent protein binding+++GO:0000033///alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0000287///magnesium ion binding+++GO:0004378///GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0102704///GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity","GO:1902527///positive regulation of protein monoubiquitination+++GO:0030948///negative regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0014029///neural crest formation+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0097502///mannosylation+++GO:0006486///protein glycosylation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0001525///angiogenesis+++GO:0036324///vascular endothelial growth factor receptor-2 signaling pathway+++GO:0032007///negative regulation of TOR signaling+++GO:0006490///oligosaccharide-lipid intermediate biosynthetic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0034605///cellular response to heat+++GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006886///intracellular protein transport+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0006915///apoptotic process+++GO:0051592///response to calcium ion+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0033577///protein glycosylation in endoplasmic reticulum+++GO:0014032///neural crest cell development+++GO:0045766///positive regulation of angiogenesis+++GO:0010595///positive regulation of endothelial cell migration","IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain","[PDCD6_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 6; AltName: Full=Apoptosis-linked gene 2 protein homolog {ECO:0000250|UniProtKB:P12815}; Short=ALG-2 {ECO:0000250|UniProtKB:P12815};+++[A0A024QZ42_HUMAN|Unreviewed]SubName: Full=HCG1985580, isoform CRA_c {ECO:0000313|EMBL:EAW50990.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000485024};+++[A0A087WZ38_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000482332};+++[D6RA21_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000424201};+++[E7EPW6_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000426003};+++[H0Y9X3_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000425370}; Flags: Fragment;+++[Q53FC3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 6 variant {ECO:0000313|EMBL:BAD97086.1}; Flags: Fragment;+++[Q86W51_HUMAN|Unreviewed]SubName: Full=PDCD6 protein {ECO:0000313|EMBL:AAH50597.1}; SubName: Full=Programmed cell death protein 6 {ECO:0000313|Ensembl:ENSP00000422691};"]
[10017,"'BCL2L10'",6,1,3.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0089720///caspase binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0007283///spermatogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007292///female gamete generation","IPR002475///Bcl2-like+++IPR020726///Apoptosis regulator, Bcl-2, BH2 motif, conserved site+++IPR036834///Blc2-like superfamily+++IPR020717///Apoptosis regulator, Bcl-2, BH1 motif, conserved site+++IPR026298///Blc2 family","[B2L10_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 10; Short=Bcl2-L-10; AltName: Full=Anti-apoptotic protein NrH; AltName: Full=Apoptosis regulator Bcl-B;+++[H0YMD5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 10 {ECO:0000313|Ensembl:ENSP00000453562};"]
[100170229,"'SRRM5'",7,2,4.5,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR038787///Serine/arginine repetitive matrix protein 5","[SRRM5_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 5;+++[Q4G0Z0_HUMAN|Unreviewed]SubName: Full=LOC100170229 protein {ECO:0000313|EMBL:AAH34980.1}; Flags: Fragment;"]
[100170841,"'EPOP'",88,111,99.5,{"$nulls":4},"GO:0070449///elongin complex+++GO:0035098///ESC/E(Z) complex+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0003682///chromatin binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0048863///stem cell differentiation+++GO:0048663///neuron fate commitment","IPR027971///Polycomb repressive complex 2-associated factor EPOP","[EPOP_HUMAN|Reviewed]RecName: Full=Elongin BC and Polycomb repressive complex 2-associated protein {ECO:0000250|UniProtKB:Q7TNS8}; AltName: Full=Proline-rich protein 28 {ECO:0000312|HGNC:HGNC:34493};"]
[10018,"'BCL2L11'",66,111,88.5,"04210///Apoptosis+++05206///MicroRNAs in cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++04215///Apoptosis - multiple species+++01521///EGFR tyrosine kinase inhibitor resistance+++05210///Colorectal cancer+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0005829///cytosol+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex+++GO:0005737///cytoplasm+++GO:0012505///endomembrane system+++GO:0043231///intracellular membrane-bounded organelle+++GO:0097140///BIM-BCL-xl complex+++GO:0005739///mitochondrion+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0097141///BIM-BCL-2 complex","GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0019901///protein kinase binding","GO:0008584///male gonad development+++GO:0048536///spleen development+++GO:0035148///tube formation+++GO:0001822///kidney development+++GO:0048538///thymus development+++GO:0009791///post-embryonic development+++GO:0001783///B cell apoptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0007420///brain development+++GO:0045787///positive regulation of cell cycle+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0048066///developmental pigmentation+++GO:0002262///myeloid cell homeostasis+++GO:0001701///in utero embryonic development+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0032464///positive regulation of protein homooligomerization+++GO:0010942///positive regulation of cell death+++GO:0070242///thymocyte apoptotic process+++GO:0001844///protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0007160///cell-matrix adhesion+++GO:0002260///lymphocyte homeostasis+++GO:0048563///post-embryonic animal organ morphogenesis+++GO:0001782///B cell homeostasis+++GO:1902263///apoptotic process involved in embryonic digit morphogenesis+++GO:0046620///regulation of organ growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0030879///mammary gland development+++GO:0043583///ear development+++GO:0006915///apoptotic process+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0043029///T cell homeostasis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0001776///leukocyte homeostasis+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0043065///positive regulation of apoptotic process+++GO:0034263///positive regulation of autophagy in response to ER overload+++GO:0048070///regulation of developmental pigmentation+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0007283///spermatogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:1903896///positive regulation of IRE1-mediated unfolded protein response+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0060154///cellular process regulating host cell cycle in response to virus+++GO:0060139///positive regulation of apoptotic process by virus","IPR015040///Bcl-x interacting, BH3 domain+++IPR014771///Apoptosis, Bim N-terminal+++IPR017288///Bcl-2-like protein 11","[B2L11_HUMAN|Reviewed]RecName: Full=Bcl-2-like protein 11; Short=Bcl2-L-11; AltName: Full=Bcl2-interacting mediator of cell death;+++[A0A0A0MRE7_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000350398};+++[A0A0C4DH20_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000354879};+++[C9J417_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000411870}; Flags: Fragment;+++[E9PAM9_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000376941}; Flags: Fragment;+++[H7BZE5_HUMAN|Unreviewed]SubName: Full=Bcl-2-like protein 11 {ECO:0000313|Ensembl:ENSP00000389225}; Flags: Fragment;"]
[100188893,"'TOMM6'",606,529,567.5,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005742///mitochondrial outer membrane translocase complex",null,"GO:0015031///protein transport","IPR029182///Mitochondrial import receptor subunit TOM6 homologue","[TOM6_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM6 homolog; AltName: Full=Overexpressed breast tumor protein; AltName: Full=Translocase of outer membrane 6 kDa subunit homolog;"]
[10019,"'SH2B3'",186,256,221,"04722///Neurotrophin signaling pathway","H00408///Type I diabetes mellitus",null,null,"GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0035591///signaling adaptor activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0005515///protein binding","GO:0007596///blood coagulation+++GO:0007165///signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0009967///positive regulation of signal transduction+++GO:0030097///hemopoiesis+++GO:0030154///cell differentiation+++GO:0035162///embryonic hemopoiesis","IPR030523///SH2B adapter protein+++IPR015012///Phenylalanine zipper+++IPR036290///Phenylalanine zipper superfamily+++IPR036860///SH2 domain superfamily+++IPR001849///Pleckstrin homology domain+++IPR035059///SH2B3, SH2 domain+++IPR000980///SH2 domain+++IPR011993///PH-like domain superfamily+++IPR030522///SH2B adapter protein 3","[SH2B3_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 3; AltName: Full=Lymphocyte adapter protein; AltName: Full=Lymphocyte-specific adapter protein Lnk; AltName: Full=Signal transduction protein Lnk;+++[B7Z7K6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54917, highly similar to Lymphocyte-specific adapter protein Lnk {ECO:0000313|EMBL:BAH13642.1};+++[F5GYM4_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000440597};+++[Q59H48_HUMAN|Unreviewed]SubName: Full=Lymphocyte adaptor protein variant {ECO:0000313|EMBL:BAD92148.1}; Flags: Fragment;+++[Q96BA5_HUMAN|Unreviewed]SubName: Full=SH2B3 protein {ECO:0000313|EMBL:AAH15786.1};+++[R4GN84_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 3 {ECO:0000313|Ensembl:ENSP00000473529}; Flags: Fragment;"]
[100191040,"'C2CD4D'",6,5,5.5,{"$nulls":4},"GO:0098793///presynapse+++GO:0005886///plasma membrane","GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding",null,"IPR035892///C2 domain superfamily+++IPR000008///C2 domain","[C2D4D_HUMAN|Reviewed]RecName: Full=C2 calcium-dependent domain-containing protein 4D;"]
[1002,"'CDH4'",365,317,341,"04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0005913///cell-cell adherens junction+++GO:0016342///catenin complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007411///axon guidance+++GO:0045773///positive regulation of axon extension+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization","IPR039808///Cadherin+++IPR000233///Cadherin, cytoplasmic domain+++IPR027397///Catenin binding domain superfamily+++IPR014868///Cadherin prodomain+++IPR020894///Cadherin conserved site+++IPR015919///Cadherin-like superfamily+++IPR002126///Cadherin-like","[CADH4_HUMAN|Reviewed]RecName: Full=Cadherin-4; AltName: Full=Retinal cadherin; Short=R-CAD; Short=R-cadherin; Flags: Precursor;+++[A0A087WX99_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000480844};+++[A0A0G2JRA4_HUMAN|Unreviewed]SubName: Full=Cadherin-4 {ECO:0000313|Ensembl:ENSP00000486568}; Flags: Fragment;"]
[10020,"'GNE'",213.34,280,246.67,"00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H00596///Nonaka distal myopathy (NM)+++H00594///Distal myopathy+++H00147///Sialuria",null,"R02705///ATP:N-acyl-D-mannosamine 6-phosphotransferase   ATP + N-Acetyl-D-mannosamine <=> ADP + N-Acetyl-D-mannosamine 6-phosphate+++R00414///UDP-N-acetyl-D-glucosamine 2-epimerase   UDP-N-acetyl-alpha-D-glucosamine + H2O <=> N-Acetyl-D-mannosamine + UDP","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0008761///UDP-N-acetylglucosamine 2-epimerase activity+++GO:0009384///N-acylmannosamine kinase activity+++GO:0016740///transferase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity+++GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0008152///metabolic process+++GO:0006054///N-acetylneuraminate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:0006045///N-acetylglucosamine biosynthetic process+++GO:0007155///cell adhesion+++GO:0016310///phosphorylation","IPR000600///ROK family+++IPR003331///UDP-N-acetylglucosamine 2-epimerase domain+++IPR020004///UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing","[GLCNE_HUMAN|Reviewed]RecName: Full=Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; AltName: Full=UDP-GlcNAc-2-epimerase/ManAc kinase; Includes: RecName: Full=UDP-N-acetylglucosamine 2-epimerase (hydrolyzing); EC=3.2.1.183; AltName: Full=UDP-GlcNAc-2-epimerase; AltName: Full=Uridine diphosphate-N-acetylglucosamine-2-epimerase; Includes: RecName: Full=N-acetylmannosamine kinase; EC=2.7.1.60; AltName: Full=ManAc kinase;+++[Q6QNY5_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59259.1};+++[Q6QNY6_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59258.1};+++[Q6QNY7_HUMAN|Unreviewed]SubName: Full=UDP-N-acetylglucosamine-2-epimerase / N-acetylmannosamine kinase {ECO:0000313|EMBL:AAS59257.1};"]
[10021,"'HCN4'",33,32,32.5,"04024///cAMP signaling pathway+++04742///Taste transduction","H00729///Sick sinus syndrome (SSS)+++H00728///Brugada syndrome (BRS)",null,null,"GO:0098855///HCN channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0005267///potassium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0042802///identical protein binding+++GO:0005216///ion channel activity+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0030552///cAMP binding+++GO:0005249///voltage-gated potassium channel activity+++GO:0086041///voltage-gated potassium channel activity involved in SA node cell action potential depolarization+++GO:0000166///nucleotide binding+++GO:0005272///sodium channel activity","GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:0055117///regulation of cardiac muscle contraction+++GO:0071321///cellular response to cGMP+++GO:0006813///potassium ion transport+++GO:0086046///membrane depolarization during SA node cell action potential+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0008015///blood circulation+++GO:0071805///potassium ion transmembrane transport+++GO:0086015///SA node cell action potential+++GO:0098719///sodium ion import across plasma membrane+++GO:0003254///regulation of membrane depolarization+++GO:0006812///cation transport+++GO:0006814///sodium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0006936///muscle contraction+++GO:0034765///regulation of ion transmembrane transport+++GO:0071320///cellular response to cAMP+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0002027///regulation of heart rate+++GO:0035725///sodium ion transmembrane transport+++GO:0042391///regulation of membrane potential","IPR030173///Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4+++IPR003938///Potassium channel, voltage-dependent, EAG/ELK/ERG+++IPR013621///Ion transport N-terminal+++IPR018490///Cyclic nucleotide-binding-like+++IPR014710///RmlC-like jelly roll fold+++IPR027359///Voltage-dependent channel domain superfamily+++IPR000595///Cyclic nucleotide-binding domain+++IPR005821///Ion transport domain+++IPR018488///Cyclic nucleotide-binding, conserved site","[HCN4_HUMAN|Reviewed]RecName: Full=Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4;"]
[10023,"'FRAT1'",14,9,11.5,"05200///Pathways in cancer+++05225///Hepatocellular carcinoma+++04310///Wnt signaling pathway+++05224///Breast cancer+++05226///Gastric cancer",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding","GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0060070///canonical Wnt signaling pathway+++GO:1904886///beta-catenin destruction complex disassembly","IPR008014///Glycogen synthase kinase-3 binding protein","[FRAT1_HUMAN|Reviewed]RecName: Full=Proto-oncogene FRAT1; AltName: Full=Frequently rearranged in advanced T-cell lymphomas 1; Short=FRAT-1;+++[D3DR49_HUMAN|Unreviewed]SubName: Full=Frequently rearranged in advanced T-cell lymphomas, isoform CRA_a {ECO:0000313|EMBL:EAW49951.1};"]
[10024,"'TROAP'",0,1,0.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0007155///cell adhesion","IPR026133///Tastin","[TROAP_HUMAN|Reviewed]RecName: Full=Tastin; AltName: Full=Trophinin-assisting protein; AltName: Full=Trophinin-associated protein;+++[B7Z5Q9_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000450306}; SubName: Full=cDNA FLJ50628, highly similar to Trophinin-associated protein {ECO:0000313|EMBL:BAH12995.1};+++[F8VR46_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446564};+++[F8VVS4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449588}; Flags: Fragment;+++[F8VVT5_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449245};+++[F8VVX4_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449866};+++[F8VXF3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449984};+++[F8VXV6_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000449032};+++[F8W052_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447244}; Flags: Fragment;+++[F8W130_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447509};+++[F8W1E3_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000446646}; Flags: Fragment;+++[F8W1U0_HUMAN|Unreviewed]SubName: Full=Tastin {ECO:0000313|Ensembl:ENSP00000447421};"]
[10025,"'MED16'",1034,958,996,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005634///nucleus","GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0003824///catalytic activity+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042809///vitamin D receptor binding","GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030518///intracellular steroid hormone receptor signaling pathway","IPR021665///Mediator complex, subunit Med16+++IPR017986///WD40-repeat-containing domain+++IPR001680///WD40 repeat+++IPR011041///Soluble quinoprotein glucose/sorbosone dehydrogenase+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[MED16_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16; AltName: Full=Mediator complex subunit 16; AltName: Full=Thyroid hormone receptor-associated protein 5; AltName: Full=Thyroid hormone receptor-associated protein complex 95 kDa component; Short=Trap95; AltName: Full=Vitamin D3 receptor-interacting protein complex 92 kDa component; Short=DRIP92;+++[A0A087WU12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YW49_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXA0_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXE7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000488370}; Flags: Fragment;+++[A0A0J9YXK9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YXL6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YY02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[A0A0J9YYC6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ5_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ7_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i4 {ECO:0000313|EMBL:ACB88883.1}; Flags: Fragment;+++[B9TWZ8_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TWZ9_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX00_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX01_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX02_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX03_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i10 {ECO:0000313|EMBL:ACB88889.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000480766}; Flags: Fragment;+++[B9TX04_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX05_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX06_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX07_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i14 {ECO:0000313|EMBL:ACB88893.1}; Flags: Fragment;+++[B9TX08_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i15 {ECO:0000313|EMBL:ACB88894.1}; Flags: Fragment;+++[B9TX09_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[B9TX10_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i17 {ECO:0000313|EMBL:ACB88896.1}; Flags: Fragment;+++[B9TX11_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX12_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX13_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i20 {ECO:0000313|EMBL:ACB88899.1}; Flags: Fragment;+++[B9TX14_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i21 {ECO:0000313|EMBL:ACB88900.1};+++[B9TX15_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i22 {ECO:0000313|EMBL:ACB88901.1}; Flags: Fragment;+++[B9TX16_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i23 {ECO:0000313|EMBL:ACB88902.1};+++[B9TX17_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i24 {ECO:0000313|EMBL:ACB88903.1};+++[B9TX18_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i25 {ECO:0000313|EMBL:ACB88904.1};+++[B9TX19_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i26 {ECO:0000313|EMBL:ACB88905.1};+++[B9TX20_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i27 {ECO:0000313|EMBL:ACB88906.1};+++[B9TX21_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i28 {ECO:0000313|EMBL:ACB88907.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000483533};+++[B9TX22_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i29 {ECO:0000313|EMBL:ACB88908.1};+++[B9TX23_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i30 {ECO:0000313|EMBL:ACB88909.1};+++[B9TX24_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i31 {ECO:0000313|EMBL:ACB88910.1};+++[B9TX25_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i32 {ECO:0000313|EMBL:ACB88911.1};+++[B9TX26_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[B9TX27_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i34 {ECO:0000313|EMBL:ACB88913.1};+++[B9TX28_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED16 variant MED16_i35 {ECO:0000313|EMBL:ACB88914.1};+++[K7EKS6_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;+++[K7EKX2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465823};+++[K7EKX6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000313|Ensembl:ENSP00000465827}; Flags: Fragment;+++[U3KQ43_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149};+++[U3KQB4_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 16 {ECO:0000256|RuleBase:RU364149}; AltName: Full=Mediator complex subunit 16 {ECO:0000256|RuleBase:RU364149}; Flags: Fragment;"]
[10026,"'PIGK'",420,573,496.5,"01100///Metabolic pathways+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis",{"$nulls":3},"GO:0042765///GPI-anchor transamidase complex+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0003923///GPI-anchor transamidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0003756///protein disulfide isomerase activity+++GO:0016787///hydrolase activity+++GO:0034235///GPI anchor binding+++GO:0005515///protein binding","GO:0006508///proteolysis+++GO:0016255///attachment of GPI anchor to protein+++GO:0006506///GPI anchor biosynthetic process","IPR028361///GPI-anchor transamidase+++IPR001096///Peptidase C13, legumain","[GPI8_HUMAN|Reviewed]RecName: Full=GPI-anchor transamidase; Short=GPI transamidase; EC=3.-.-.-; AltName: Full=GPI8 homolog; Short=hGPI8; AltName: Full=Phosphatidylinositol-glycan biosynthesis class K protein; Short=PIG-K; Flags: Precursor;+++[A6NEM5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000352041};+++[B1AK81_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000388854}; SubName: Full=Phosphatidylinositol glycan, class K, isoform CRA_c {ECO:0000313|EMBL:EAX06382.1};+++[S4R3M5_HUMAN|Unreviewed]SubName: Full=GPI-anchor transamidase {ECO:0000313|Ensembl:ENSP00000474518}; Flags: Fragment;"]
[100271715,"'ARHGEF33'",7,8,7.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0035023///regulation of Rho protein signal transduction","IPR035899///Dbl homology (DH) domain superfamily+++IPR000219///Dbl homology (DH) domain","[ARG33_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 33;+++[H7C1C9_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 33 {ECO:0000313|Ensembl:ENSP00000399688};"]
[100271849,"'MEF2B'",58.72,53.43,56.075,"04022///cGMP-PKG signaling pathway+++04371///Apelin signaling pathway","H01613///Follicular lymphoma",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0042826///histone deacetylase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007517///muscle organ development","IPR033896///MADS MEF2-like+++IPR036879///Transcription factor, MADS-box superfamily+++IPR002100///Transcription factor, MADS-box","[MEF2B_HUMAN|Reviewed]RecName: Full=Myocyte-specific enhancer factor 2B; AltName: Full=RSRFR2; AltName: Full=Serum response factor-like protein 2;+++[A0A024R7K5_HUMAN|Unreviewed]SubName: Full=MADS box transcription enhancer factor 2, polypeptide B (Myocyte enhancer factor 2B), isoform CRA_a {ECO:0000313|EMBL:EAW84793.1};+++[B3KQ23_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386480}; SubName: Full=cDNA FLJ32648 fis, clone SYNOV2001451, highly similar to MYOCYTE-SPECIFIC ENHANCER FACTOR 2B {ECO:0000313|EMBL:BAG51885.1};+++[B8ZZJ5_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386784};+++[C9J4J4_HUMAN|Unreviewed]SubName: Full=Myocyte-specific enhancer factor 2B {ECO:0000313|Ensembl:ENSP00000386374};"]
[100271927,"'RASA4B'",117.73,145.41,131.57,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0005543///phospholipid binding+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0071277///cellular response to calcium ion+++GO:0043087///regulation of GTPase activity+++GO:0046580///negative regulation of Ras protein signal transduction","IPR035892///C2 domain superfamily+++IPR011993///PH-like domain superfamily+++IPR039360///Ras GTPase-activating protein+++IPR023152///Ras GTPase-activating protein, conserved site+++IPR001936///Ras GTPase-activating domain+++IPR001562///Zinc finger, Btk motif+++IPR000008///C2 domain+++IPR037777///RASA4, PH domain+++IPR008936///Rho GTPase activation protein+++IPR001849///Pleckstrin homology domain","[RAS4B_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4B;+++[F5GXT2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000440982};+++[F8W6L0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000303968};"]
[100272147,"'CMC4'",60,32.34,46.17,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space+++GO:0032991///protein-containing complex","GO:0019901///protein kinase binding+++GO:0043539///protein serine/threonine kinase activator activity","GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0008283///cell proliferation","IPR027179///Mature-T-Cell Proliferation I type+++IPR009069///Cysteine alpha-hairpin motif superfamily","[CMC4_HUMAN|Reviewed]RecName: Full=Cx9C motif-containing protein 4; AltName: Full=Mature T-cell proliferation 1 neighbor protein; AltName: Full=Mature T-cell proliferation-1 type A; Short=MTCP-1 type A; AltName: Full=Protein p8 MTCP-1; Short=p8MTCP1;+++[A0A0G2JKI4_HUMAN|Unreviewed]SubName: Full=Protein p13 MTCP-1 {ECO:0000313|Ensembl:ENSP00000427132}; Flags: Fragment;+++[Q9NRK3_HUMAN|Unreviewed]SubName: Full=p8 protein {ECO:0000313|EMBL:AAF76750.1};"]
[100287036,"'LOC100287036'",0,3,1.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol",null,"GO:0060325///face morphogenesis+++GO:0048705///skeletal system morphogenesis+++GO:0001701///in utero embryonic development+++GO:0001894///tissue homeostasis+++GO:0035264///multicellular organism growth+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0060348///bone development","IPR020683///Ankyrin repeat-containing domain+++IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily","[B7Z1S9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59013 {ECO:0000313|EMBL:BAH11615.1};"]
[100287171,"'WASHC1'",3379,3610,3494.5,"04212///Longevity regulating pathway - worm+++04144///Endocytosis",{"$nulls":3},"GO:0071203///WASH complex+++GO:0005814///centriole+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005829///cytosol+++GO:0071437///invadopodium+++GO:0055038///recycling endosome membrane+++GO:0000145///exocyst+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005856///cytoskeleton+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm+++GO:0005770///late endosome+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005776///autophagosome+++GO:0031410///cytoplasmic vesicle","GO:0043014///alpha-tubulin binding+++GO:0003779///actin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0015031///protein transport+++GO:0043553///negative regulation of phosphatidylinositol 3-kinase activity+++GO:0010507///negative regulation of autophagy+++GO:0030335///positive regulation of cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0006887///exocytosis+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0031396///regulation of protein ubiquitination+++GO:0022617///extracellular matrix disassembly+++GO:0042147///retrograde transport, endosome to Golgi+++GO:1990126///retrograde transport, endosome to plasma membrane","IPR021854///WASH1, WAHD domain+++IPR003124///WH2 domain+++IPR028290///WASH1","[WASH1_HUMAN|Reviewed]RecName: Full=WASH complex subunit 1 {ECO:0000312|HGNC:HGNC:24361}; AltName: Full=CXYorf1-like protein on chromosome 9; AltName: Full=Protein FAM39E; AltName: Full=WAS protein family homolog 1;+++[A0A2R8YDD3_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 1 {ECO:0000313|Ensembl:ENSP00000494459}; Flags: Fragment;+++[A9QQ12_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71499.1}; Flags: Fragment;+++[A9QQ13_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71500.1}; Flags: Fragment;+++[A9QQ14_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71501.1}; Flags: Fragment;+++[A9QQ15_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71502.1}; Flags: Fragment;+++[A9QQ16_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71503.1}; Flags: Fragment;+++[A9QQ17_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71504.1}; Flags: Fragment;+++[A9QQ18_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71505.1}; Flags: Fragment;+++[A9QQ19_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71506.1}; Flags: Fragment;+++[A9QQ20_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71507.1}; Flags: Fragment;+++[A9QQ21_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71508.1}; Flags: Fragment;+++[A9QQ22_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71509.1}; Flags: Fragment;+++[A9QQ23_HUMAN|Unreviewed]SubName: Full=Actin nucleation promoting factor {ECO:0000313|EMBL:ABX71510.1}; Flags: Fragment;"]
[100287387,"'LOC100287387'",1,4,2.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0003677///DNA binding+++GO:0046983///protein dimerization activity","GO:0043066///negative regulation of apoptotic process+++GO:0006351///transcription, DNA-templated+++GO:0030335///positive regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045668///negative regulation of osteoblast differentiation","IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR019351///Protein of unknown function DUF2039+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[TWIST_XENLA|diamond]RecName: Full=Twist-related protein; AltName: Full=T18; AltName: Full=X-twist;+++[TWST1_EULFU|diamond]RecName: Full=Twist-related protein 1;+++[TWST2_HUMAN|diamond]RecName: Full=Twist-related protein 2; AltName: Full=Class A basic helix-loop-helix protein 39; Short=bHLHa39; AltName: Full=Dermis-expressed protein 1; Short=Dermo-1;+++[TWST2_MOUSE|diamond]RecName: Full=Twist-related protein 2; AltName: Full=Dermis-expressed protein 1; Short=Dermo-1;+++[TWST2_RAT|diamond]RecName: Full=Twist-related protein 2;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100287482,"'SMKR1'",7,2,4.5,{"$nulls":7},"IPR037760///Small lysine-rich protein 1","[SMKR1_HUMAN|Reviewed]RecName: Full=Small lysine-rich protein 1;"]
[100287896,"'LOC100287896'",39,43,41,"04140///Autophagy - animal+++00785///Lipoic acid metabolism+++04137///Mitophagy - animal+++01100///Metabolic pathways",null,null,"R07769///lipoyl-[acp]:protein N6-lipoyltransferase Lipoyl-[acp] + Apoprotein <=> Protein N6-(lipoyl)lysine + Acyl-carrier protein+++R07766///octanoyl-[acp]:protein N6-octanoyltransferase Octanoyl-[acp] + Apoprotein <=> Protein N6-(octanoyl)lysine + Acyl-carrier protein","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0033819///lipoyl(octanoyl) transferase activity+++GO:0016874///ligase activity+++GO:0102555///octanoyl transferase activity (acting on glycine-cleavage complex H protein)","GO:0009249///protein lipoylation+++GO:0034641///cellular nitrogen compound metabolic process+++GO:2000376///positive regulation of oxygen metabolic process","IPR009057///Homeobox-like domain superfamily+++IPR006600///HTH CenpB-type DNA-binding domain","[Q8TB74_HUMAN|Unreviewed]SubName: Full=Similar to Cytochrome c, somatic {ECO:0000313|EMBL:AAH19340.1};"]
[100287898,"'TTC34'",13,12,12.5,{"$nulls":7},"IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR019734///Tetratricopeptide repeat","[TTC34_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 34; Short=TPR repeat protein 34;+++[A0A1C7CYW7_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 34 {ECO:0000313|Ensembl:ENSP00000383873};"]
[100287932,"'TIMM23'",834.24,584.89,709.565,"04212///Longevity regulating pathway - worm","H00032///Thyroid cancer",null,null,"GO:0016021///integral component of membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0031305///integral component of mitochondrial inner membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport","IPR005681///Mitochondrial inner membrane translocase complex, subunit Tim23","[TIM23_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim23;+++[Q6X2S9_HUMAN|Unreviewed]SubName: Full=Translocase of the inner mitochondrial membrane {ECO:0000313|EMBL:AAP83315.1}; Flags: Fragment;"]
[100288142,"'NBPF20'",265.22,291.48,278.35,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0003723///RNA binding",null,"IPR010630///Neuroblastoma breakpoint family (NBPF) domain","[NBPFK_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 20;+++[A0A075B7A3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000471335};+++[A0A087WU97_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000478481};+++[H7BY70_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 20 {ECO:0000313|Ensembl:ENSP00000358380};"]
[100288332,"'NPIPA5'",351.3,439.89,395.595,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR009443///Nuclear pore complex interacting protein","[NPIA5_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[A0A067ZUK6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28873.1}; Flags: Fragment;+++[A0A067ZUK7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28878.1}; Flags: Fragment;+++[A0A067ZUK9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28883.1}; Flags: Fragment;+++[A0A067ZUL0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28888.1}; Flags: Fragment;+++[A0A067ZUL2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28893.1}; Flags: Fragment;+++[A0A067ZUL3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28898.1}; Flags: Fragment;+++[A0A067ZUL5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28903.1}; Flags: Fragment;+++[A0A067ZUL6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28908.1}; Flags: Fragment;+++[A0A067ZUL8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28913.1}; Flags: Fragment;+++[A0A067ZVG2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28875.1}; Flags: Fragment;+++[A0A067ZVG5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28880.1}; Flags: Fragment;+++[A0A067ZVG8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28885.1}; Flags: Fragment;+++[A0A067ZVH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28890.1}; Flags: Fragment;+++[A0A067ZVH5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28895.1}; Flags: Fragment;+++[A0A067ZVH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28900.1}; Flags: Fragment;+++[A0A067ZVI1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28905.1}; Flags: Fragment;+++[A0A067ZVI6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28910.1}; Flags: Fragment;+++[A0A067ZWN6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28874.1}; Flags: Fragment;+++[A0A067ZWN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28879.1}; Flags: Fragment;+++[A0A067ZWP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28884.1}; Flags: Fragment;+++[A0A067ZWP4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28889.1}; Flags: Fragment;+++[A0A067ZWP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28894.1}; Flags: Fragment;+++[A0A067ZWQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28899.1}; Flags: Fragment;+++[A0A067ZWQ3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28904.1}; Flags: Fragment;+++[A0A067ZWQ8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28909.1}; Flags: Fragment;+++[A0A067ZWR0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28914.1}; Flags: Fragment;+++[A0A067ZXG0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28872.1}; Flags: Fragment;+++[A0A067ZXG1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28877.1}; Flags: Fragment;+++[A0A067ZXG4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28882.1}; Flags: Fragment;+++[A0A067ZXG6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28887.1}; Flags: Fragment;+++[A0A067ZXG7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28892.1}; Flags: Fragment;+++[A0A067ZXH0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28897.1}; Flags: Fragment;+++[A0A067ZXH2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28902.1}; Flags: Fragment;+++[A0A067ZXH4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28907.1}; Flags: Fragment;+++[A0A067ZXH7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28912.1}; Flags: Fragment;+++[A0A067ZXH9_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28917.1}; Flags: Fragment;+++[A0A067ZXM6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28876.1}; Flags: Fragment;+++[A0A067ZXN0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28881.1}; Flags: Fragment;+++[A0A067ZXN4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28886.1}; Flags: Fragment;+++[A0A067ZXN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28891.1}; Flags: Fragment;+++[A0A067ZXP1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28896.1}; Flags: Fragment;+++[A0A067ZXP5_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28901.1}; Flags: Fragment;+++[A0A067ZXP7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28906.1}; Flags: Fragment;+++[A0A067ZXQ0_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein {ECO:0000313|EMBL:AHY28911.1}; Flags: Fragment;+++[A0A0B4J1W7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000389275};+++[A0A0J9YW65_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000487831}; Flags: Fragment;+++[A0A0J9YWV6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000488135};+++[E9PJ88_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435611};+++[H0YED6_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000435610}; Flags: Fragment;+++[H0YEP2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000436257}; Flags: Fragment;+++[H0YF59_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000437314}; Flags: Fragment;+++[Q9NRE7_HUMAN|Unreviewed]SubName: Full=KIAA0220-like protein {ECO:0000313|EMBL:AAF82267.1}; SubName: Full=Nuclear pore complex-interacting protein family member A5 {ECO:0000313|Ensembl:ENSP00000330634};"]
[100288413,"'ERVMER34-1'",20,38,29,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region",null,null,"IPR018154///TLV/ENV coat polyprotein","[MER34_HUMAN|Reviewed]RecName: Full=Endogenous retroviral envelope protein HEMO {ECO:0000305}; AltName: Full=Endogenous retrovirus group MER34 member 1 Env polyprotein {ECO:0000305}; AltName: Full=HERV-MER_4q12 provirus ancestral Env polyprotein; AltName: Full=Human endogenous MER34 (medium-reiteration-frequency-family-34) open reading frame {ECO:0000303|PubMed:28739914}; AltName: Full=Human endogenous MER34 ORF {ECO:0000303|PubMed:28739914}; Short=HEMO {ECO:0000303|PubMed:28739914}; Contains: RecName: Full=Endogenous retroviral envelope protein HEMO, secreted form {ECO:0000305}; AltName: Full=Endogenous retroviral envelope protein HEMO, 48 kDa form; Flags: Precursor;"]
[100288520,"'USP17L15'",0,1,0.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum","GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008234///cysteine-type peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0016787///hydrolase activity","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0042981///regulation of apoptotic process","IPR018200///Ubiquitin specific protease, conserved site+++IPR006861///Hyaluronan/mRNA-binding protein+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR028889///Ubiquitin specific protease domain+++IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase","[U17LF_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 15; EC=3.4.19.12;+++[A0A087WUW7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 17-like protein 15 {ECO:0000313|Ensembl:ENSP00000483519};"]
[100288562,"'LOC100288562'",0,0.5,0.25,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004527///exonuclease activity+++GO:0003676///nucleic acid binding",null,"IPR031736///Elongin A binding-protein 1+++IPR013520///Exonuclease, RNase T/DNA polymerase III+++IPR036397///Ribonuclease H superfamily+++IPR034922///RNA exonuclease 1-like, exonuclease domain+++IPR012337///Ribonuclease H-like superfamily","[GOR_HUMAN|diamond]RecName: Full=Putative exonuclease GOR; EC=3.1.-.-; AltName: Full=Antigen GOR homolog; AltName: Full=RNA exonuclease 1 homolog-like 1;+++[GOR_PANTR|diamond]RecName: Full=Exonuclease GOR; EC=3.1.-.-; AltName: Full=Antigen GOR; AltName: Full=RNA exonuclease 1 homolog-like;+++[PQE1_CAEEL|diamond]RecName: Full=Putative RNA exonuclease pqe-1; AltName: Full=PolyQ enhancer protein 1;+++[REXO1_HUMAN|diamond]RecName: Full=RNA exonuclease 1 homolog; EC=3.1.-.-; AltName: Full=Elongin-A-binding protein 1; Short=EloA-BP1; AltName: Full=Transcription elongation factor B polypeptide 3-binding protein 1;+++[REXO1_MOUSE|diamond]RecName: Full=RNA exonuclease 1 homolog; EC=3.1.-.-; AltName: Full=Transcription elongation factor B polypeptide 3-binding protein 1;"]
[100288695,"'LIMS4'",39.94,39.89,39.915,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005925///focal adhesion","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0045216///cell-cell junction organization","IPR017351///LIM and senescent cell antigen-like-containing domain protein 1+++IPR001781///Zinc finger, LIM-type","[LIMS3_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 3; AltName: Full=Particularly interesting new Cys-His protein 3; Short=PINCH-3;+++[LIMS4_HUMAN|Reviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein 4; AltName: Full=LIM and senescent cell antigen-like-containing domain protein 3-like;+++[A0A0J9YXC7_HUMAN|Unreviewed]RecName: Full=LIM and senescent cell antigen-like-containing domain protein {ECO:0000256|PIRNR:PIRNR038003};"]
[100288801,"'FRG2C'",0,2,1,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0019843///rRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0045296///cadherin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006413///translational initiation+++GO:0008283///cell proliferation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000027///ribosomal large subunit assembly+++GO:0045766///positive regulation of angiogenesis+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0001525///angiogenesis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001570///vasculogenesis+++GO:0006412///translation+++GO:0007155///cell adhesion","IPR026245///Protein FRG2","[FRG2C_HUMAN|Reviewed]RecName: Full=Protein FRG2-like-2; AltName: Full=FSHD region gene 2 protein family member C; AltName: Full=HSA3-FRG2;+++[C9JUX3_HUMAN|Unreviewed]SubName: Full=Protein FRG2-like-2 {ECO:0000313|Ensembl:ENSP00000419432};"]
[100289187,"'TMEM225B'",13.92,9,11.46,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0010923///negative regulation of phosphatase activity","IPR033542///Transmembrane protein 225","[T225B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 225B {ECO:0000312|HGNC:HGNC:53075};"]
[100289279,"'CNTNAP3C'",4.63,17.85,11.24,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region",null,"GO:0008037///cell recognition+++GO:0007155///cell adhesion","IPR002181///Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain+++IPR000742///EGF-like domain+++IPR036056///Fibrinogen-like, C-terminal+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR028873///Contactin-associated protein-like 3+++IPR000421///Coagulation factor 5/8 C-terminal domain+++IPR008979///Galactose-binding-like domain superfamily+++IPR001791///Laminin G domain","[CNT3B_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3B; AltName: Full=Cell recognition molecule Caspr3b; Flags: Precursor;+++[CNTP3_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 3; AltName: Full=Cell recognition molecule Caspr3; Flags: Precursor;+++[CNTP4_HUMAN|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP4_MOUSE|diamond]RecName: Full=Contactin-associated protein-like 4; AltName: Full=Cell recognition molecule Caspr4; Flags: Precursor;+++[CNTP5_CHICK|diamond]RecName: Full=Contactin-associated protein-like 5; AltName: Full=Cell recognition molecule Caspr5; Flags: Precursor;"]
[100289561,"'LOC100289561'",86.41,99.1,92.755,{"$nulls":4},"GO:0032389///MutLalpha complex","GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding","GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0006298///mismatch repair+++GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR003594///Histidine kinase/HSP90-like ATPase+++IPR036890///Histidine kinase/HSP90-like ATPase superfamily+++IPR001909///Krueppel-associated box+++IPR038973///DNA mismatch repair protein MutL/Mlh/Pms","[PM2P3_HUMAN|diamond]RecName: Full=Putative postmeiotic segregation increased 2-like protein 3; AltName: Full=PMS2-related protein 3; AltName: Full=Postmeiotic segregation increased 2-like protein 9; AltName: Full=Postmeiotic segregation increased protein 5; AltName: Full=Putative postmeiotic segregation increased 2 pseudogene 3;+++[RBAK_HUMAN|diamond]RecName: Full=RB-associated KRAB zinc finger protein; AltName: Full=RB-associated KRAB repressor; Short=hRBaK; AltName: Full=Zinc finger protein 769;+++[ZN510_HUMAN|diamond]RecName: Full=Zinc finger protein 510;+++[ZNF12_HUMAN|diamond]RecName: Full=Zinc finger protein 12; AltName: Full=Gonadotropin-inducible ovary transcription repressor 3; Short=GIOT-3; AltName: Full=Zinc finger protein 325; AltName: Full=Zinc finger protein KOX3;+++[ZNF12_MOUSE|diamond]RecName: Full=Zinc finger protein 12;"]
[100289635,"'ZNF605'",246,252,249,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR017125///PR-domain zinc finger protein PRDM5-like+++IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type","[ZN605_HUMAN|Reviewed]RecName: Full=Zinc finger protein 605;+++[Q8WW51_HUMAN|Unreviewed]SubName: Full=ZNF605 protein {ECO:0000313|EMBL:AAH20877.1}; Flags: Fragment;"]
[100289678,"'ZNF783'",103,109,106,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR022137///Protein of unknown function DUF3669, zinc finger protein","[ZN783_HUMAN|Reviewed]RecName: Full=Protein ZNF783;"]
[100293516,"'ZNF587B'",36.22,56,46.11,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily","[Z587B_HUMAN|Reviewed]RecName: Full=Zinc finger protein 587B;+++[M0QY62_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000469623};+++[M0R1N2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 587B {ECO:0000313|Ensembl:ENSP00000472004}; Flags: Fragment;"]
[100302652,"'GPR75-ASB3'",91.05,28,59.525,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0035556///intracellular signal transduction+++GO:0016567///protein ubiquitination","IPR036036///SOCS box-like domain superfamily+++IPR037329///Ankyrin repeat and SOCS box protein 3, SOCS box domain+++IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR020683///Ankyrin repeat-containing domain+++IPR001496///SOCS box domain","[ASB3_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and SOCS box protein 3; Short=ASB-3;+++[A0A0A6YYF3_HUMAN|Unreviewed]SubName: Full=Protein GPR75-ASB3 {ECO:0000313|Ensembl:ENSP00000385085};"]
[100302736,"'TMED7-TICAM2'",126.13,182.74,154.435,"05161///Hepatitis B+++04620///Toll-like receptor signaling pathway+++05133///Pertussis+++04064///NF-kappa B signaling pathway+++04217///Necroptosis",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030134///COPII-coated ER to Golgi transport vesicle","GO:0005543///phospholipid binding","GO:0006886///intracellular protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007030///Golgi organization","IPR035897///Toll/interleukin-1 receptor homology (TIR) domain superfamily+++IPR009038///GOLD domain+++IPR015720///TMP21-related+++IPR015718///Transmembrane emp24 domain-containing protein 7+++IPR036598///GOLD domain superfamily+++IPR000157///Toll/interleukin-1 receptor homology (TIR) domain","[TCAM2_HUMAN|Reviewed]RecName: Full=TIR domain-containing adapter molecule 2; Short=TICAM-2; AltName: Full=Putative NF-kappa-B-activating protein 502; AltName: Full=TRIF-related adapter molecule; AltName: Full=Toll-like receptor adaptor protein 3; AltName: Full=Toll/interleukin-1 receptor domain-containing protein; Short=MyD88-4;+++[TMED7_HUMAN|Reviewed]RecName: Full=Transmembrane emp24 domain-containing protein 7; AltName: Full=p24 family protein gamma-3; Short=p24gamma3; AltName: Full=p27; Flags: Precursor;+++[A0A0A6YYA0_HUMAN|Unreviewed]SubName: Full=Protein TMED7-TICAM2 {ECO:0000313|Ensembl:ENSP00000333650};"]
[100303755,"'PET117'",24.89,24.5,24.695,{"$nulls":4},"GO:0005739///mitochondrion","GO:0004402///histone acetyltransferase activity+++GO:0030274///LIM domain binding","GO:0033617///mitochondrial respiratory chain complex IV assembly","IPR031568///Protein Pet117, mitochondrial","[PT117_HUMAN|Reviewed]RecName: Full=Protein PET117 homolog, mitochondrial; Flags: Precursor;+++[L0R6F6_HUMAN|Unreviewed]SubName: Full=Alternative protein CSRP2BP {ECO:0000313|EMBL:CCO13715.1};"]
[100310846,"'ANKRD61'",2,0,1,{"$nulls":7},"IPR036770///Ankyrin repeat-containing domain superfamily+++IPR002110///Ankyrin repeat+++IPR020683///Ankyrin repeat-containing domain","[ANR61_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 61;"]
[100316904,"'SAP25'",18,21,19.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0006355///regulation of transcription, DNA-templated","IPR029163///Histone deacetylase complex subunit SAP25","[SAP25_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP25; AltName: Full=25 kDa Sin3-associated polypeptide; AltName: Full=Sin3 corepressor complex subunit SAP25;+++[A0A087WYF9_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP25 {ECO:0000313|Ensembl:ENSP00000481773};"]
[10036,"'CHAF1A'",116,98,107,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0033186///CAF-1 complex","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0070087///chromo shadow domain binding+++GO:0051082///unfolded protein binding+++GO:0003682///chromatin binding","GO:0031497///chromatin assembly+++GO:0006260///DNA replication+++GO:0006281///DNA repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006334///nucleosome assembly+++GO:0007049///cell cycle","IPR029105///Chromatin assembly factor 1 subunit A, C-terminal+++IPR029091///Chromatin assembly factor 1 subunit A, N-terminal+++IPR022043///Chromatin assembly factor 1 subunit A","[CAF1A_HUMAN|Reviewed]RecName: Full=Chromatin assembly factor 1 subunit A; Short=CAF-1 subunit A; AltName: Full=Chromatin assembly factor I p150 subunit; Short=CAF-I 150 kDa subunit; Short=CAF-I p150; Short=hp150;+++[D6W625_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1, subunit A (P150), isoform CRA_a {ECO:0000313|EMBL:EAW69225.1};+++[K7EJF1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000465142}; Flags: Fragment;+++[K7EME9_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466475}; Flags: Fragment;+++[K7ENC7_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000466888}; Flags: Fragment;+++[K7EPA1_HUMAN|Unreviewed]SubName: Full=Chromatin assembly factor 1 subunit A {ECO:0000313|Ensembl:ENSP00000467296}; Flags: Fragment;"]
[10038,"'PARP2'",228,211,219.5,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04210///Apoptosis+++04212///Longevity regulating pathway - worm",null,"M00296///BER complex",null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990404///protein ADP-ribosylase activity","GO:0006471///protein ADP-ribosylation+++GO:0006281///DNA repair+++GO:0061051///positive regulation of cell growth involved in cardiac muscle cell development+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0006284///base-excision repair+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0018312///peptidyl-serine ADP-ribosylation+++GO:1901215///negative regulation of neuron death","IPR004102///Poly(ADP-ribose) polymerase, regulatory domain+++IPR036616///Poly(ADP-ribose) polymerase, regulatory domain superfamily+++IPR012317///Poly(ADP-ribose) polymerase, catalytic domain+++IPR036930///WGR domain superfamily+++IPR008893///WGR domain","[PARP2_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 2; Short=PARP-2; Short=hPARP-2; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 2; Short=ARTD2; AltName: Full=NAD(+) ADP-ribosyltransferase 2; Short=ADPRT-2; AltName: Full=Poly[ADP-ribose] synthase 2; Short=pADPRT-2;+++[E9PJ27_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 2 {ECO:0000313|Ensembl:ENSP00000431867};+++[G3V167_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[H0YH02_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114}; Flags: Fragment;"]
[100381270,"'ZBED6'",26,110,68,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated","IPR036236///Zinc finger C2H2 superfamily+++IPR037220///Zinc finger BED domain+++IPR012337///Ribonuclease H-like superfamily+++IPR008906///HAT, C-terminal dimerisation domain+++IPR003656///Zinc finger, BED-type","[ZBED6_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 6 {ECO:0000303|PubMed:20016685};"]
[10039,"'PARP3'",487,492,489.5,"04217///Necroptosis+++04214///Apoptosis - fly+++03410///Base excision repair+++04212///Longevity regulating pathway - worm+++04210///Apoptosis",null,"M00296///BER complex",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0005815///microtubule organizing center+++GO:0005730///nucleolus+++GO:0005814///centriole+++GO:0005856///cytoskeleton","GO:0016757///transferase activity, transferring glycosyl groups+++GO:1990404///protein ADP-ribosylase activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0003824///catalytic activity+++GO:0016740///transferase activity","GO:0051106///positive regulation of DNA ligation+++GO:0060236///regulation of mitotic spindle organization+++GO:0006302///double-strand break repair+++GO:0070212///protein poly-ADP-ribosylation+++GO:0006281///DNA repair+++GO:1905662///negative regulation of telomerase RNA reverse transcriptase activity+++GO:0000723///telomere maintenance+++GO:0006471///protein ADP-ribosylation+++GO:1990166///protein localization to site of double-strand break","IPR012317///Poly(ADP-ribose) polymerase, catalytic domain+++IPR004102///Poly(ADP-ribose) polymerase, regulatory domain+++IPR008893///WGR domain+++IPR031275///Poly [ADP-ribose] polymerase 3+++IPR036930///WGR domain superfamily+++IPR036616///Poly(ADP-ribose) polymerase, regulatory domain superfamily","[PARP3_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 3; Short=PARP-3; Short=hPARP-3; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 3; Short=ARTD3; AltName: Full=IRT1; AltName: Full=NAD(+) ADP-ribosyltransferase 3; Short=ADPRT-3; AltName: Full=Poly[ADP-ribose] synthase 3; Short=pADPRT-3;+++[A0A024R2X5_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[C9J9C7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417625}; Flags: Fragment;+++[F8WAY7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 3 {ECO:0000313|Ensembl:ENSP00000417396};"]
[1004,"'CDH6'",403.99,482,442.995,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0009986///cell surface+++GO:0016342///catenin complex+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007219///Notch signaling pathway+++GO:0034332///adherens junction organization","IPR002126///Cadherin-like+++IPR015919///Cadherin-like superfamily+++IPR039808///Cadherin+++IPR020894///Cadherin conserved site+++IPR027397///Catenin binding domain superfamily+++IPR000233///Cadherin, cytoplasmic domain","[CADH6_HUMAN|Reviewed]RecName: Full=Cadherin-6; AltName: Full=Kidney cadherin; Short=K-cadherin; Flags: Precursor;+++[D6RF86_HUMAN|Unreviewed]SubName: Full=Cadherin-6 {ECO:0000313|Ensembl:ENSP00000424843};+++[L8EAC6_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH6 {ECO:0000313|EMBL:CCQ43288.1};"]
[10040,"'TOM1L1'",292,239,265.5,"04714///Thermogenesis+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++04137///Mitophagy - animal+++04140///Autophagy - animal",null,"M00154///Cytochrome c oxidase",null,"GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005623///cell+++GO:0005795///Golgi stack+++GO:0005768///endosome+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0030276///clathrin binding+++GO:0043130///ubiquitin binding+++GO:0005515///protein binding+++GO:0030295///protein kinase activator activity+++GO:0017124///SH3 domain binding","GO:0006886///intracellular protein transport+++GO:0045839///negative regulation of mitotic nuclear division+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:2000278///regulation of DNA biosynthetic process+++GO:0015031///protein transport+++GO:0031954///positive regulation of protein autophosphorylation","IPR002014///VHS domain+++IPR008942///ENTH/VHS+++IPR038425///GAT domain superfamily+++IPR014645///Target of Myb protein 1+++IPR027428///TOM1-like protein 1+++IPR004152///GAT domain","[TM1L1_HUMAN|Reviewed]RecName: Full=TOM1-like protein 1; AltName: Full=Src-activating and signaling molecule protein; AltName: Full=Target of Myb-like protein 1;+++[I3L0N2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458219};+++[I3L1G1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000458809}; Flags: Fragment;+++[I3L1Q1_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459003}; Flags: Fragment;+++[I3L1T2_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000459079};+++[I3L367_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460213}; Flags: Fragment;+++[I3L3M3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460565};+++[I3L3T4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000460721};+++[I3L4G0_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461215}; Flags: Fragment;+++[I3L4I4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461284};+++[I3L4N3_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461396}; Flags: Fragment;+++[I3NI44_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000461876};+++[J3KQU4_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000408958}; SubName: Full=Target of myb1-like 1 (Chicken), isoform CRA_b {ECO:0000313|EMBL:EAW94552.1};+++[K7EP47_HUMAN|Unreviewed]SubName: Full=TOM1-like protein 1 {ECO:0000313|Ensembl:ENSP00000467227}; Flags: Fragment;+++[Q8NI65_HUMAN|Unreviewed]SubName: Full=OK/KNS-CL.3 {ECO:0000313|EMBL:BAB93522.1};"]
[10042,"'HMGXB4'",245,218,231.5,{"$nulls":4},"GO:0016589///NURF complex+++GO:0005634///nucleus","GO:0003677///DNA binding","GO:0016055///Wnt signaling pathway+++GO:0008333///endosome to lysosome transport+++GO:0030178///negative regulation of Wnt signaling pathway","IPR025228///Domain of unknown function DUF4171+++IPR036910///High mobility group box domain superfamily+++IPR009071///High mobility group box domain","[HMGX4_HUMAN|Reviewed]RecName: Full=HMG domain-containing protein 4; AltName: Full=HMG box-containing protein 4; AltName: Full=High mobility group protein 2-like 1; AltName: Full=Protein HMGBCG;+++[B0QXZ8_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000415500}; Flags: Fragment;+++[B0QXZ9_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000401658}; Flags: Fragment;+++[F8WDU7_HUMAN|Unreviewed]SubName: Full=HMG domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000395532};+++[Q2M3X1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI04757.1}; SubName: Full=High-mobility group protein 2-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW60048.1};+++[Q2T9L2_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAI11374.1}; Flags: Fragment;+++[Q6P681_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH62413.1}; Flags: Fragment;+++[Q6PJ09_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH25303.1}; Flags: Fragment;+++[Q6PJC1_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH17326.1}; Flags: Fragment;+++[Q7Z641_HUMAN|Unreviewed]SubName: Full=HMGXB4 protein {ECO:0000313|EMBL:AAH52624.1}; Flags: Fragment;"]
[10043,"'TOM1'",1283,961,1122,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0005769///early endosome+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005623///cell+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0035577///azurophil granule membrane","GO:0030276///clathrin binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0043312///neutrophil degranulation+++GO:0016197///endosomal transport+++GO:0006897///endocytosis","IPR008942///ENTH/VHS+++IPR002014///VHS domain+++IPR014645///Target of Myb protein 1+++IPR038425///GAT domain superfamily+++IPR004152///GAT domain","[TOM1_HUMAN|Reviewed]RecName: Full=Target of Myb protein 1;+++[B0QY01_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000393714}; Flags: Fragment;+++[B0QY02_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000389789}; Flags: Fragment;+++[B3KUF5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39747 fis, clone SMINT2017432, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53417.1};+++[B3KUU1_HUMAN|Unreviewed]SubName: Full=Target of myb1 (Chicken), isoform CRA_a {ECO:0000313|EMBL:EAW60053.1}; SubName: Full=cDNA FLJ40607 fis, clone THYMU2012273, highly similar to Target of Myb protein 1 {ECO:0000313|EMBL:BAG53553.1};+++[F8WAW7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000385906};+++[F8WB30_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000397492};+++[F8WBB0_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000390429};+++[F8WE29_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000394944};+++[H7BYN7_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000379085};+++[Q6UW50_HUMAN|Unreviewed]SubName: Full=TOM1 {ECO:0000313|EMBL:AAQ89339.1}; SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000371465};+++[V9GYF4_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000476698}; Flags: Fragment;+++[V9GZ68_HUMAN|Unreviewed]SubName: Full=Target of Myb protein 1 {ECO:0000313|Ensembl:ENSP00000477471}; Flags: Fragment;"]
[10045,"'SH2D3A'",22,30,26,"04910///Insulin signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0042995///cell projection+++GO:0005622///intracellular+++GO:0005764///lysosome+++GO:0005856///cytoskeleton+++GO:0005938///cell cortex+++GO:0005794///Golgi apparatus+++GO:0001891///phagocytic cup","GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005070///SH3/SH2 adaptor activity","GO:0007254///JNK cascade+++GO:0007264///small GTPase mediated signal transduction+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0009967///positive regulation of signal transduction","IPR001895///Ras guanine-nucleotide exchange factors catalytic domain+++IPR023578///Ras guanine nucleotide exchange factor domain superfamily+++IPR036860///SH2 domain superfamily+++IPR036964///Ras guanine-nucleotide exchange factor catalytic domain superfamily+++IPR000980///SH2 domain","[SH23A_HUMAN|Reviewed]RecName: Full=SH2 domain-containing protein 3A; AltName: Full=Novel SH2-containing protein 1;+++[A8K2M8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78700, highly similar to Homo sapiens SH2 domain containing 3A, mRNA {ECO:0000313|EMBL:BAF82982.1};+++[M0QZQ6_HUMAN|Unreviewed]SubName: Full=SH2 domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000470700}; Flags: Fragment;"]
[10046,"'MAMLD1'",933,1386,1159.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00609///46,XY disorders of sex development (Other)",null,null,"GO:0005575///cellular_component+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008584///male gonad development","IPR026131///Mastermind-like domain-containing protein 1","[MAMD1_HUMAN|Reviewed]RecName: Full=Mastermind-like domain-containing protein 1; AltName: Full=F18; AltName: Full=Protein CG1;+++[F8WAK3_HUMAN|Unreviewed]SubName: Full=Mastermind-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000351765}; Flags: Fragment;+++[L0R6K4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAMLD1 {ECO:0000313|EMBL:CCO13767.1};"]
[100462977,"'MTRNR2L1'",2380,2014.07,2197.035,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","IPR028139///Humanin family","[HMN1_HUMAN|Reviewed]RecName: Full=Humanin-like 1 {ECO:0000305}; Short=HN1 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 1 {ECO:0000312|HGNC:HGNC:37155};"]
[100462981,"'MTRNR2L2'",104866.56,138329.23,121597.895,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","IPR028139///Humanin family","[HMN2_HUMAN|Reviewed]RecName: Full=Humanin-like 2 {ECO:0000305}; Short=HN2 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 2 {ECO:0000312|HGNC:HGNC:37156};"]
[100462983,"'MTRNR2L3'",687.09,607.68,647.385,"03013///RNA transport+++05164///Influenza A",null,"M00427///Nuclear pore complex",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","IPR028139///Humanin family","[HMN3_HUMAN|Reviewed]RecName: Full=Humanin-like 3 {ECO:0000305}; Short=HN3 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 3 {ECO:0000312|HGNC:HGNC:37157};"]
[100463285,"'MTRNR2L4'",1,1,1,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","IPR028139///Humanin family","[HMN4_HUMAN|Reviewed]RecName: Full=Humanin-like 4 {ECO:0000305}; Short=HN4 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 4 {ECO:0000312|HGNC:HGNC:37161};"]
[100463482,"'MTRNR2L6'",514.91,438.28,476.595,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","IPR028139///Humanin family","[HMN6_HUMAN|Reviewed]RecName: Full=Humanin-like 6 {ECO:0000305}; Short=HN6 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 6 {ECO:0000312|HGNC:HGNC:37163};"]
[100463486,"'MTRNR2L8'",57073.41,79809.52,68441.465,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","IPR028139///Humanin family","[HMN8_HUMAN|Reviewed]RecName: Full=Humanin-like 8 {ECO:0000305}; Short=HN8 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 8 {ECO:0000312|HGNC:HGNC:37165};"]
[100463487,"'MTRNR2L9'",801.19,1059.23,930.21,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0048019///receptor antagonist activity","GO:1900116///extracellular negative regulation of signal transduction+++GO:1900118///negative regulation of execution phase of apoptosis","IPR028139///Humanin family","[HMN9_HUMAN|Reviewed]RecName: Full=Humanin-like 9 {ECO:0000305}; Short=HN9 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 9 {ECO:0000312|HGNC:HGNC:37166};"]
[100463488,"'MTRNR2L10'",444.85,315.98,380.415,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0048019///receptor antagonist activity","GO:1900118///negative regulation of execution phase of apoptosis+++GO:1900116///extracellular negative regulation of signal transduction","IPR028139///Humanin family","[HMN10_HUMAN|Reviewed]RecName: Full=Humanin-like 10 {ECO:0000305}; Short=HN10 {ECO:0000303|PubMed:19477263}; AltName: Full=MT-RNR2-like protein 10 {ECO:0000312|HGNC:HGNC:37167};"]
[10048,"'RANBP9'",712,799,755.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex","GO:0019899///enzyme binding+++GO:0008536///Ran GTPase binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007020///microtubule nucleation+++GO:0007411///axon guidance+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000165///MAPK cascade","IPR006595///CTLH, C-terminal LisH motif+++IPR001870///B30.2/SPRY domain+++IPR035782///Ran binding protein 9/10, SPRY domain+++IPR006594///LIS1 homology motif+++IPR024964///CTLH/CRA C-terminal to LisH motif domain+++IPR013144///CRA domain+++IPR003877///SPRY domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily","[RANB9_HUMAN|Reviewed]RecName: Full=Ran-binding protein 9; Short=RanBP9; AltName: Full=BPM-L; AltName: Full=BPM90; AltName: Full=Ran-binding protein M; Short=RanBPM {ECO:0000303|PubMed:11470507, ECO:0000303|PubMed:17467196}; AltName: Full=RanBP7;+++[A0A024QZW3_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_a {ECO:0000313|EMBL:EAW55345.1};+++[A0A024R014_HUMAN|Unreviewed]SubName: Full=RAN binding protein 9, isoform CRA_b {ECO:0000313|EMBL:EAW55344.1};"]
[10049,"'DNAJB6'",2006,1798,1902,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0031072///heat shock protein binding+++GO:0001671///ATPase activator activity+++GO:0042802///identical protein binding+++GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0060710///chorio-allantoic fusion+++GO:0032781///positive regulation of ATPase activity+++GO:1900034///regulation of cellular response to heat+++GO:0060715///syncytiotrophoblast cell differentiation involved in labyrinthine layer development+++GO:0090084///negative regulation of inclusion body assembly+++GO:0030198///extracellular matrix organization+++GO:0030036///actin cytoskeleton organization+++GO:0006457///protein folding+++GO:0045109///intermediate filament organization+++GO:0060717///chorion development+++GO:0032880///regulation of protein localization+++GO:0034504///protein localization to nucleus+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated","IPR018253///DnaJ domain, conserved site+++IPR001623///DnaJ domain+++IPR036869///Chaperone J-domain superfamily","[DNJB6_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily B member 6; AltName: Full=HHDJ1; AltName: Full=Heat shock protein J2; Short=HSJ-2; AltName: Full=MRJ; AltName: Full=MSJ-1;+++[A0A0J9YX62_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000488263};+++[C9J2C4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000400665}; Flags: Fragment;+++[C9J2P2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000410643}; Flags: Fragment;+++[C9JB42_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000391690}; Flags: Fragment;+++[C9JDR7_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396240}; Flags: Fragment;+++[C9JDX6_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000403407}; Flags: Fragment;+++[C9JN01_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000389599}; Flags: Fragment;+++[E9PH18_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000396267};+++[F8WCZ4_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 6 {ECO:0000313|Ensembl:ENSP00000415201};+++[Q49A72_HUMAN|Unreviewed]SubName: Full=DNAJB6 protein {ECO:0000313|EMBL:AAH43270.1};+++[Q75MP3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DNAJB6 {ECO:0000313|EMBL:AAS07521.1}; Flags: Fragment;"]
[100499483,"'CCDC180'",47,29,38,{"$nulls":4},"GO:0070062///extracellular exosome",null,null,"IPR026701///Coiled-coil domain-containing protein 180+++IPR027914///Domain of unknown function DUF4456+++IPR028089///Domain of unknown function DUF4455","[CC180_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 180;+++[B4DZK1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50036, weakly similar to Myosin-11 {ECO:0000313|EMBL:BAG64113.1};"]
[1005,"'CDH7'",2,1,1.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0034332///adherens junction organization+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","IPR002126///Cadherin-like+++IPR039808///Cadherin+++IPR020894///Cadherin conserved site+++IPR015919///Cadherin-like superfamily+++IPR027397///Catenin binding domain superfamily+++IPR000233///Cadherin, cytoplasmic domain","[CADH7_HUMAN|Reviewed]RecName: Full=Cadherin-7; Flags: Precursor;+++[F5H5X9_HUMAN|Unreviewed]SubName: Full=Cadherin-7 {ECO:0000313|Ensembl:ENSP00000443030};+++[Q8IY78_HUMAN|Unreviewed]SubName: Full=CDH7 protein {ECO:0000313|EMBL:AAH36786.1};"]
[100505385,"'IQCJ-SCHIP1'",1044.45,961.53,1002.99,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0043194///axon initial segment+++GO:0030424///axon","GO:0005515///protein binding","GO:0051494///negative regulation of cytoskeleton organization","IPR039045///Schwannomin interacting protein 1+++IPR029362///Fusion protein IQCJ-SCHIP1, N-terminal+++IPR015649///Schwannomin interacting protein 1, C-terminal","[IQIP1_HUMAN|Reviewed]RecName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000312|HGNC:HGNC:38842};+++[A0A1W2PP08_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491220}; Flags: Fragment;+++[A0A1W2PPY3_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000491419}; Flags: Fragment;+++[A0A1W2PQT1_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492132}; Flags: Fragment;+++[A0A1W2PR78_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492358}; Flags: Fragment;+++[A0A1W2PR91_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492497}; Flags: Fragment;+++[A0A1W2PRV6_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492461}; Flags: Fragment;+++[A0A1W2PRY4_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000492853}; Flags: Fragment;+++[C9J366_HUMAN|Unreviewed]SubName: Full=IQCJ-SCHIP1 readthrough transcript protein {ECO:0000313|Ensembl:ENSP00000417305};"]
[100505478,"'TEX48'",0,1,0.5,{"$nulls":8},"[TEX48_HUMAN|Reviewed]RecName: Full=Testis-expressed protein 48 {ECO:0000305};+++[A0A1B0GUM3_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 48 {ECO:0000313|Ensembl:ENSP00000490169};"]
[100505549,"'LOC100505549'",3,3,3,{"$nulls":7},"IPR004269///Folate receptor+++IPR018143///Folate receptor-like","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100505573,"'INAFM2'",269,320,294.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005246///calcium channel regulator activity",null,"IPR029162///TRP-interacting helix, InaF motif","[INAM2_HUMAN|Reviewed]RecName: Full=Putative transmembrane protein INAFM2 {ECO:0000305}; AltName: Full=InaF-motif-containing protein 2 {ECO:0000312|HGNC:HGNC:35165}; AltName: Full=Osteogenesis up-regulated transcript 1 {ECO:0000303|PubMed:19531736};"]
[100505591,"'LRRC3C'",1,1,1,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space","GO:0043565///sequence-specific DNA binding+++GO:0004860///protein kinase inhibitor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0043312///neutrophil degranulation+++GO:0090156///cellular sphingolipid homeostasis+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0006672///ceramide metabolic process+++GO:1900060///negative regulation of ceramide biosynthetic process+++GO:0006351///transcription, DNA-templated+++GO:0006469///negative regulation of protein kinase activity+++GO:0019221///cytokine-mediated signaling pathway","IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily+++IPR003591///Leucine-rich repeat, typical subtype","[LRR3C_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 3C; Flags: Precursor;"]
[100505679,"'UBE2Q2L'",4,3,3.5,{"$nulls":4},"GO:0005576///extracellular region+++GO:0031258///lamellipodium membrane+++GO:0070062///extracellular exosome+++GO:0005925///focal adhesion+++GO:0005796///Golgi lumen+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0043202///lysosomal lumen","GO:0019901///protein kinase binding","GO:0030206///chondroitin sulfate biosynthetic process+++GO:0048771///tissue remodeling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030207///chondroitin sulfate catabolic process+++GO:0035556///intracellular signal transduction+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0001525///angiogenesis+++GO:0000187///activation of MAPK activity+++GO:0008283///cell proliferation+++GO:0008347///glial cell migration","IPR039005///CSPG repeat+++IPR001791///Laminin G domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily","[U2Q2L_HUMAN|Reviewed]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;"]
[100505876,"'CEBPZOS'",595.14,575.16,585.15,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","IPR037764///Protein CEBPZOS","[CEBOS_HUMAN|Reviewed]RecName: Full=Protein CEBPZOS {ECO:0000305}; AltName: Full=CEBPZ antisense RNA 1 {ECO:0000312|HGNC:HGNC:49288}; AltName: Full=CEBPZ opposite strand {ECO:0000312|HGNC:HGNC:49288};"]
[100505989,"'SMIM31'",0,4,2,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",{"$nulls":3},"[SIM31_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 31 {ECO:0000305};"]
[100506012,"'PPP5D1'",17,11,14,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005622///intracellular","GO:0005509///calcium ion binding","GO:0019722///calcium-mediated signaling","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013235///PPP domain","[PP5D1_HUMAN|Reviewed]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[A0A087WY80_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000481586}; Flags: Fragment;+++[M0R196_HUMAN|Unreviewed]SubName: Full=Protein PPP5D1 {ECO:0000313|Ensembl:ENSP00000471730}; Flags: Fragment;"]
[100506084,"'ARL17B'",92.18,88.85,90.515,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport","IPR006689///Small GTPase superfamily, ARF/SAR type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR031687///ADP-ribosylation factor-like protein 17, C-terminal","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[A8K0M5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76374 {ECO:0000313|EMBL:BAF82279.1};+++[I3L1A0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000458681}; Flags: Fragment;+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L2E4_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459606};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};+++[Q9BVU5_HUMAN|Unreviewed]SubName: Full=ARL17 protein {ECO:0000313|EMBL:AAH00924.2}; Flags: Fragment;"]
[100506115,"'SMIM25'",5,1,3,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013235///PPP domain","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100506127,"'GVQW3'",44.01,63.9,53.955,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding","GO:0008285///negative regulation of cell proliferation+++GO:0007165///signal transduction","IPR038441///THAP-type zinc finger superfamily+++IPR006612///THAP-type zinc finger+++IPR008906///HAT, C-terminal dimerisation domain+++IPR025398///Domain of unknown function DUF4371+++IPR012337///Ribonuclease H-like superfamily","[GVQW3_HUMAN|Reviewed]RecName: Full=Protein GVQW3 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 3 {ECO:0000305};+++[A0A0U1RQW1_HUMAN|Unreviewed]SubName: Full=Protein GVQW3 {ECO:0000313|Ensembl:ENSP00000489195};"]
[100506144,"'TMEM35B'",158,151,154.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IPR032808///DoxX family","[TM35B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 35B; AltName: Full=ZMYM6 neighbor protein; Flags: Precursor;"]
[100506164,"'HSFX1'",17.16,8.41,12.785,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0061408///positive regulation of transcription from RNA polymerase II promoter in response to heat stress+++GO:0006355///regulation of transcription, DNA-templated+++GO:0034605///cellular response to heat","IPR000232///Heat shock factor (HSF)-type, DNA-binding+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR037032///Heat shock transcription factor, X-linked+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR027725///Heat shock transcription factor family","[HSFX1_HUMAN|Reviewed]RecName: Full=Heat shock transcription factor, X-linked;+++[A0A140VK21_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 21 {ECO:0000313|EMBL:AEE61158.1};"]
[100506243,"'KRBOX1'",28,30,29,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box","[KRBX1_HUMAN|Reviewed]RecName: Full=KRAB domain-containing protein 1;+++[A0A024R2N1_HUMAN|Unreviewed]SubName: Full=HCG2039480, isoform CRA_a {ECO:0000313|EMBL:EAW64687.1};"]
[100506248,"'PTMAP9'",490.36,250.29,370.325,"05169///Epstein-Barr virus infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0042393///histone binding+++GO:0033613///activating transcription factor binding","GO:0043486///histone exchange+++GO:0006351///transcription, DNA-templated","IPR004931///Prothymosin/parathymosin","[PTMA_BOVIN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_HUMAN|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha-1;+++[PTMA_MOUSE|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_PONAB|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;+++[PTMA_RAT|diamond]RecName: Full=Prothymosin alpha; Contains: RecName: Full=Prothymosin alpha, N-terminally processed; Contains: RecName: Full=Thymosin alpha;"]
[100506514,"'LOC100506514'",0,2,1,{"$nulls":4},"GO:0005622///intracellular","GO:0005525///GTP binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity","GO:0006164///purine nucleotide biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR019734///Tetratricopeptide repeat+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR005225///Small GTP-binding protein domain+++IPR031545///Putative TPR-like repeat+++IPR018236///SAICAR synthetase, conserved site+++IPR006689///Small GTPase superfamily, ARF/SAR type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR028923///SAICAR synthetase/ADE2, N-terminal+++IPR001005///SANT/Myb domain+++IPR033626///Class II PurE+++IPR035893///PurE domain superfamily+++IPR000031///PurE domain","[ZKSC2_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 2; AltName: Full=Zinc finger protein 694;+++[ZSC20_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31; AltName: Full=Zinc finger protein 360; AltName: Full=Zinc finger protein KOX29;+++[ZSC20_MOUSE|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 20; AltName: Full=Zinc finger protein 31;+++[ZSC29_HUMAN|diamond]RecName: Full=Zinc finger and SCAN domain-containing protein 29; AltName: Full=Zinc finger protein 690;"]
[100506540,"'SPTY2D1OS'",2,0,1,"00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00010///Glycolysis / Gluconeogenesis+++01120///Microbial metabolism in diverse environments+++00640///Propanoate metabolism+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00620///Pyruvate metabolism+++04922///Glucagon signaling pathway","H01762///Muscle glycogen storage disease+++H00069///Glycogen storage diseases (GSD)+++H01946///Glycogen storage disease type XI",null,"R00703///(S)-Lactate:NAD+ oxidoreductase (S)-Lactate + NAD+ <=> Pyruvate + NADH + H++++R03104///3-Mercaptolactate:NAD+ oxidoreductase 3-Mercaptolactate + NAD+ <=> Mercaptopyruvate + NADH + H++++R01000///2-hydroxybutyrate:NAD+ oxidoreductase 2-Hydroxybutanoic acid + NAD+ <=> 2-Oxobutanoate + NADH + H+","GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","GO:0015031///protein transport+++GO:0006915///apoptotic process+++GO:0005975///carbohydrate metabolic process+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006464///cellular protein modification process+++GO:0043065///positive regulation of apoptotic process+++GO:0019752///carboxylic acid metabolic process","IPR018108///Mitochondrial substrate/solute carrier+++IPR022383///Lactate/malate dehydrogenase, C-terminal+++IPR001236///Lactate/malate dehydrogenase, N-terminal+++IPR001557///L-lactate/malate dehydrogenase+++IPR036291///NAD(P)-binding domain superfamily+++IPR016135///Ubiquitin-conjugating enzyme/RWD-like+++IPR015955///Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal+++IPR023395///Mitochondrial carrier domain superfamily+++IPR008883///Ubiquitin E2 variant, N-terminal","[SPTOS_HUMAN|Reviewed]RecName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000305}; AltName: Full=SPTY2D1 antisense RNA 1 {ECO:0000312|HGNC:HGNC:44122}; AltName: Full=SPTY2D1 opposite strand {ECO:0000312|HGNC:HGNC:44122};+++[A0A0U1RQQ8_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489122};+++[A0A0U1RQZ7_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489253};+++[A0A0U1RR47_HUMAN|Unreviewed]SubName: Full=Putative transmembrane protein SPTY2D1OS {ECO:0000313|Ensembl:ENSP00000489337};"]
[100506564,"'THEGL'",16,11,13.5,{"$nulls":7},"IPR006623///Testicular haploid expressed repeat","[THEGL_HUMAN|Reviewed]RecName: Full=Testicular haploid expressed gene protein-like; AltName: Full=Theg spermatid-like protein;"]
[100506571,"'LOC100506571'",5,5,5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR018379///BEN domain","[Q9NT86_HUMAN|Unreviewed]SubName: Full=HCG42237 {ECO:0000313|EMBL:EAW69830.1};"]
[100506581,"'C16orf95'",31,39,35,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR027919///Protein of unknown function DUF4568","[CP095_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C16orf95;+++[A0A087X224_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000484646};+++[H3BNZ7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C16orf95 {ECO:0000313|Ensembl:ENSP00000455079};"]
[100506658,"'OCLN'",45,43.01,44.005,"04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++05160///Hepatitis C","H00840///Band-like calcification with simplified gyration and polymicrogyria (BLC-PMG)",null,null,"GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005911///cell-cell junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0005923///bicellular tight junction+++GO:0016327///apicolateral plasma membrane+++GO:0030139///endocytic vesicle+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0070673///response to interleukin-18+++GO:0045216///cell-cell junction organization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0065003///protein-containing complex assembly+++GO:2000810///regulation of bicellular tight junction assembly+++GO:0070830///bicellular tight junction assembly","IPR002958///Occludin+++IPR010844///Occludin homology domain+++IPR036259///MFS transporter superfamily+++IPR008253///Marvel domain+++IPR031176///ELL/occludin family","[OCLN_HUMAN|Reviewed]RecName: Full=Occludin;+++[A0A0G2JMZ8_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};+++[A0A0G2JPF2_HUMAN|Unreviewed]SubName: Full=Occludin {ECO:0000313|Ensembl:ENSP00000483480};+++[A8K3T2_HUMAN|Unreviewed]RecName: Full=Occludin {ECO:0000256|PIRNR:PIRNR005993};"]
[100506736,"'SLFN12L'",1,0,0.5,"04137///Mitophagy - animal+++03022///Basal transcription factors+++05168///Herpes simplex infection+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005524///ATP binding","GO:0006366///transcription by RNA polymerase II+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0016075///rRNA catabolic process+++GO:0043966///histone H3 acetylation+++GO:0016078///tRNA catabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","IPR029684///Schlafen family+++IPR007421///Schlafen, AAA domain+++IPR038461///Schlafen, AAA domain superfamily","[SN12L_HUMAN|Reviewed]RecName: Full=Schlafen family member 12-like;+++[A0A0D9SGD9_HUMAN|Unreviewed]SubName: Full=Schlafen family member 12-like {ECO:0000313|Ensembl:ENSP00000487397};"]
[100507050,"'TPBGL'",12,7,9.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR003591///Leucine-rich repeat, typical subtype+++IPR032675///Leucine-rich repeat domain superfamily+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR001611///Leucine-rich repeat","[TPBGL_HUMAN|Reviewed]RecName: Full=Trophoblast glycoprotein-like; Flags: Precursor;"]
[100507055,"'LRCOL1'",3,4,3.5,{"$nulls":4},"GO:0005576///extracellular region","GO:0008047///enzyme activator activity","GO:0043085///positive regulation of catalytic activity+++GO:0007586///digestion+++GO:0032094///response to food+++GO:0016042///lipid catabolic process","IPR001981///Colipase","[LRCL1_HUMAN|Reviewed]RecName: Full=Leucine-rich colipase-like protein 1; Flags: Precursor;+++[A0A087WT69_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000477635};+++[A0A087WYD7_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000481713};+++[A0A087WZ94_HUMAN|Unreviewed]SubName: Full=Leucine-rich colipase-like protein 1 {ECO:0000313|Ensembl:ENSP00000482471};"]
[100507290,"'ZNF865'",1096,1230,1163,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN865_HUMAN|Reviewed]RecName: Full=Zinc finger protein 865;+++[A0A0D9SG26_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 865 {ECO:0000313|Ensembl:ENSP00000487098};"]
[100507421,"'TMEM178B'",543,923,733,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","IPR039625///Transmembrane protein 178A/B+++IPR004031///PMP-22/EMP/MP20/Claudin superfamily","[T178B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 178B; Flags: Precursor;+++[A0A087X1B3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 178B {ECO:0000313|Ensembl:ENSP00000484025};"]
[100507436,"'MICA'",3616,2845.45,3230.725,"05167///Kaposi's sarcoma-associated herpesvirus infection","H00288///Familial Mediterranean fever (FMF)",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046703///natural killer cell lectin-like receptor binding+++GO:0030881///beta-2-microglobulin binding","GO:0050776///regulation of immune response+++GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0051607///defense response to virus+++GO:0009408///response to heat+++GO:0046629///gamma-delta T cell activation+++GO:0045953///negative regulation of natural killer cell mediated cytotoxicity+++GO:0030101///natural killer cell activation+++GO:0019835///cytolysis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0032815///negative regulation of natural killer cell activation+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0042742///defense response to bacterium+++GO:0016032///viral process+++GO:0002418///immune response to tumor cell+++GO:0001913///T cell mediated cytotoxicity","IPR007110///Immunoglobulin-like domain+++IPR010579///MHC class I, alpha chain, C-terminal+++IPR001039///MHC class I alpha chain, alpha1 alpha2 domains+++IPR003006///Immunoglobulin/major histocompatibility complex, conserved site+++IPR003597///Immunoglobulin C1-set+++IPR011162///MHC classes I/II-like antigen recognition protein+++IPR011161///MHC class I-like antigen recognition-like+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR037055///MHC class I-like antigen recognition-like superfamily",{"$cut":{"chars":22248,"head":"[MICA_HUMAN|Reviewed]RecName: Full=MHC class I polypeptide-related sequence A; Short=MIC-A; Flags: Precursor;+++[A0A023SER7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74089.1}; Flags: Fragment;+++[A0A023SGA8_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I polypeptide-related protein A {ECO:0000313|EMBL:AHX74088.1}; Flags: Fragment;+++[A0A024RCL3_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A, isoform CRA_a {ECO:0000313|EMBL:EAX03394.1};+++[A0A0F6UUZ2_HUMAN|Unreviewed]SubName: Full=Truncated MHC class I chain-related protein A {ECO:0000313|EMBL:AKE78870.1}; Flags: Fragment;+++[A0A0G2JJ55_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000405177};+++[A0A0G2JK11_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|Ensembl:ENSP00000412992};+++[A0A0K1NWU9_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75046.1}; Flags: Fragment;+++[A0A0K1NXC7_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75047.1}; Flags: Fragment;+++[A0A0K1NXW1_HUMAN|Unreviewed]SubName: Full=MHC class I polypeptide-related sequence A {ECO:0000313|EMBL:AKU75045.1}; Flags: Fragment;+++[A0A0M3LAT3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11906.1}; Flags: Fragment;+++[A0A0M3LAU3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11916.1}; Flags: Fragment;+++[A0A0M3LAV0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11908.1}; Flags: Fragment;+++[A0A0M3LAV5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11926.1}; Flags: Fragment;+++[A0A0M3LAW0_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11918.1}; Flags: Fragment;+++[A0A0M3LAW3_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11936.1}; Flags: Fragment;+++[A0A0M3LAW8_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11928.1}; Flags: Fragment;+++[A0A0M3LAX6_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11938.1}; Flags: Fragment;+++[A0A0M3LAX7_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11946.1}; Flags: Fragment;+++[A0A0M3LAY5_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11948.1}; Flags: Fragment;+++[A0A0M3LB05_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11905.1}; Flags: Fragment;+++[A0A0M3LB16_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11903.1}; Flags: Fragment;+++[A0A0M3LB17_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11915.1}; Flags: Fragment;+++[A0A0M3LB24_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11913.1}; Flags: Fragment;+++[A0A0M3LB25_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11925.1}; Flags: Fragment;+++[A0A0M3LB32_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11923.1}; Flags: Fragment;+++[A0A0M3LB33_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11935.1}; Flags: Fragment;+++[A0A0M3LB39_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11945.1}; Flags: Fragment;+++[A0A0M3LB40_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11933.1}; Flags: Fragment;+++[A0A0M3LB48_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11955.1}; Flags: Fragment;+++[A0A0M3LB49_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11943.1}; Flags: Fragment;+++[A0A0M3LB59_HUMAN|Unreviewed]SubName: Full=MHC class I related sequence A {ECO:0000313|EMBL:AIO11953.1}; Flags: Fragment;+++[A0A0M3LB64_HUMAN|Unreviewed]SubName: Ful"}}]
[100507462,"'GVQW2'",1,2,1.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR025271///Domain of unknown function DUF4061+++IPR036236///Zinc finger C2H2 superfamily","[GVQW2_HUMAN|Reviewed]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};"]
[100507507,"'LOC100507507'",306,186,246,{"$nulls":8},"[A0A2J8V2S2_PONAB|diamond]SubName: Full=T0078241 isoform 1 {ECO:0000313|EMBL:PNJ51828.1};"]
[100507588,"'TGFBR3L'",132,134,133,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR001507///Zona pellucida domain","[TGR3L_HUMAN|Reviewed]RecName: Full=Transforming growth factor-beta receptor type 3-like protein; AltName: Full=TGF-beta receptor type-3-like protein; Short=TGFR-3L; AltName: Full=Transforming growth factor-beta receptor type III-like protein; Short=TGF-beta receptor type III-like protein;"]
[100507607,"'NPIPB9'",16.26,13,14.63,"01100///Metabolic pathways+++00650///Butanoate metabolism",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm",null,null,"IPR009443///Nuclear pore complex interacting protein","[NPIB9_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B9;+++[F8VUA1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B9 {ECO:0000313|Ensembl:ENSP00000350444};"]
[100507679,"'MUC22'",1,1,1,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IPR028199///Mucin, catalytic, TM and cytoplasmic tail domain","[MUC22_HUMAN|Reviewed]RecName: Full=Mucin-22; AltName: Full=Panbronchiolitis-related mucin-like protein 1; Flags: Precursor;+++[M1TIV1_HUMAN|Unreviewed]SubName: Full=Mucin 22 {ECO:0000313|EMBL:AGG40961.1};"]
[100507747,"'C13orf46'",16,15,15.5,{"$nulls":7},"IPR040020///Uncharacterized protein C13orf46-like","[CM046_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C13orf46 {ECO:0000305};"]
[100509620,"'LOC100509620'",0,1,0.5,"04923///Regulation of lipolysis in adipocytes+++03320///PPAR signaling pathway","H02106///Genetic obesity",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015267///channel activity","GO:0055085///transmembrane transport","IPR015686///Aquaporin 7+++IPR000425///Major intrinsic protein+++IPR023271///Aquaporin-like","[A0A075B734_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000456868};"]
[10051,"'SMC4'",114,139,126.5,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005694///chromosome","GO:0003697///single-stranded DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0030261///chromosome condensation+++GO:0007049///cell cycle+++GO:0007076///mitotic chromosome condensation+++GO:0051383///kinetochore organization+++GO:0045132///meiotic chromosome segregation+++GO:0000070///mitotic sister chromatid segregation+++GO:0010032///meiotic chromosome condensation+++GO:0051276///chromosome organization+++GO:0051301///cell division","IPR003395///RecF/RecN/SMC, N-terminal+++IPR036277///SMCs flexible hinge superfamily+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR024704///Structural maintenance of chromosomes protein+++IPR010935///SMCs flexible hinge","[SMC4_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 4; Short=SMC protein 4; Short=SMC-4; AltName: Full=Chromosome-associated polypeptide C; Short=hCAP-C; AltName: Full=XCAP-C homolog;+++[B3KXX5_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[C9IYK2_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418820}; Flags: Fragment;+++[C9J578_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417999}; Flags: Fragment;+++[C9J9E4_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000417612}; Flags: Fragment;+++[C9JJ64_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420817}; Flags: Fragment;+++[C9JR83_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000420121}; Flags: Fragment;+++[C9JVD8_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419360}; Flags: Fragment;+++[C9JWF0_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000419247}; Flags: Fragment;+++[E9PD53_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[F8WCB7_HUMAN|Unreviewed]SubName: Full=Structural maintenance of chromosomes protein 4 {ECO:0000313|Ensembl:ENSP00000418434};+++[Q58F29_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH01557.1}; Flags: Fragment;+++[Q6NSG3_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH70161.1}; Flags: Fragment;+++[Q6P169_HUMAN|Unreviewed]SubName: Full=SMC4 protein {ECO:0000313|EMBL:AAH65259.1}; Flags: Fragment;"]
[10052,"'GJC1'",105,107,106,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0014704///intercalated disc+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005921///gap junction+++GO:0016021///integral component of membrane+++GO:0005922///connexin complex","GO:0086077///gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling+++GO:0005216///ion channel activity+++GO:0086020///gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling","GO:0086014///atrial cardiac muscle cell action potential+++GO:0086021///SA node cell to atrial cardiac muscle cell communication by electrical coupling+++GO:0048738///cardiac muscle tissue development+++GO:0048468///cell development+++GO:0007043///cell-cell junction assembly+++GO:0086053///AV node cell to bundle of His cell communication by electrical coupling+++GO:0006936///muscle contraction+++GO:0007268///chemical synaptic transmission+++GO:0016264///gap junction assembly+++GO:0007601///visual perception+++GO:0001570///vasculogenesis","IPR038359///Connexin, N-terminal domain superfamily+++IPR019570///Gap junction protein, cysteine-rich domain+++IPR000500///Connexin+++IPR017990///Connexin, conserved site+++IPR013092///Connexin, N-terminal+++IPR002265///Gap junction alpha-6 protein (Cx45)","[CXG1_HUMAN|Reviewed]RecName: Full=Gap junction gamma-1 protein; AltName: Full=Connexin-45; Short=Cx45; AltName: Full=Gap junction alpha-7 protein;"]
[100526693,"'ARPC4-TTLL3'",221.62,247.16,234.39,{"$nulls":4},"GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton","GO:0003779///actin binding+++GO:0070735///protein-glycine ligase activity","GO:0018094///protein polyglycylation+++GO:0006464///cellular protein modification process+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030041///actin filament polymerization+++GO:0030833///regulation of actin filament polymerization","IPR004344///Tubulin-tyrosine ligase/Tubulin polyglutamylase+++IPR034666///Arp2/3 complex subunit 2/4+++IPR027753///Tubulin monoglycylase TTLL3+++IPR008384///Actin-related protein 2/3 complex subunit 4","[A0A0A6YYG9_HUMAN|Unreviewed]SubName: Full=Protein ARPC4-TTLL3 {ECO:0000313|Ensembl:ENSP00000380427};+++[F8WCF6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000256|PIRNR:PIRNR039100};+++[F8WE39_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000402163};+++[H7C0A3_HUMAN|Unreviewed]SubName: Full=ARPC4-TTLL3 readthrough {ECO:0000313|Ensembl:ENSP00000393764}; Flags: Fragment;"]
[100526694,"'MSANTD3-TMEFF1'",34.74,47.52,41.13,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding","GO:0007275///multicellular organism development+++GO:0010468///regulation of gene expression+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007517///muscle organ development","IPR013032///EGF-like, conserved site+++IPR000742///EGF-like domain+++IPR036058///Kazal domain superfamily+++IPR002350///Kazal domain","[TEFF1_HUMAN|Reviewed]RecName: Full=Tomoregulin-1; Short=TR-1; AltName: Full=H7365; AltName: Full=Transmembrane protein with EGF-like and one follistatin-like domain; Flags: Precursor;+++[A0A0A6YYJ0_HUMAN|Unreviewed]SubName: Full=Protein MSANTD3-TMEFF1 {ECO:0000313|Ensembl:ENSP00000424768};"]
[100526737,"'RBM14-RBM4'",15.07,3.56,9.315,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0098534///centriole assembly+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0002190///cap-independent translational initiation+++GO:0008380///RNA splicing+++GO:0045087///innate immune response+++GO:0030154///cell differentiation+++GO:0032055///negative regulation of translation in response to stress+++GO:0017148///negative regulation of translation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002192///IRES-dependent translational initiation of linear mRNA+++GO:0045947///negative regulation of translational initiation+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0046685///response to arsenic-containing substance+++GO:0097167///circadian regulation of translation+++GO:0006397///mRNA processing+++GO:0035278///miRNA mediated inhibition of translation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0046822///regulation of nucleocytoplasmic transport","IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR034507///RBM14, RNA recognition motif 2+++IPR034506///RBM14, RNA recognition motif 1+++IPR000504///RNA recognition motif domain","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0A0MSL8_HUMAN|Unreviewed]SubName: Full=RBM14-RBM4 readthrough {ECO:0000313|Ensembl:ENSP00000395880};+++[A0A0A6YYI9_HUMAN|Unreviewed]SubName: Full=Protein RBM14-RBM4 {ECO:0000313|Ensembl:ENSP00000421279};"]
[100526739,"'CENPS-CORT'",44.52,32.56,38.54,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0071821///FANCM-MHF complex+++GO:0005576///extracellular region","GO:0046982///protein heterodimerization activity+++GO:0005179///hormone activity","GO:0010469///regulation of signaling receptor activity","IPR029003///CENP-S/Mhf1+++IPR009072///Histone-fold+++IPR033554///Centromere protein S+++IPR018142///Somatostatin/Cortistatin, C-terminal","[CENPS_HUMAN|Reviewed]RecName: Full=Centromere protein S; Short=CENP-S; AltName: Full=Apoptosis-inducing TAF9-like domain-containing protein 1; AltName: Full=FANCM-associated histone fold protein 1 {ECO:0000303|PubMed:20347428}; AltName: Full=FANCM-interacting histone fold protein 1 {ECO:0000303|PubMed:20347429}; AltName: Full=Fanconi anemia-associated polypeptide of 16 kDa;+++[A0A087WT10_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000473401};+++[A0A0U1RQL5_HUMAN|Unreviewed]SubName: Full=CENPS-CORT readthrough {ECO:0000313|Ensembl:ENSP00000489060}; SubName: Full=Centromere protein S {ECO:0000313|Ensembl:ENSP00000489524};"]
[100526760,"'ABHD14A-ACY1'",23.18,21.95,22.565,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01230///Biosynthesis of amino acids+++00220///Arginine biosynthesis+++01210///2-Oxocarboxylic acid metabolism+++01130///Biosynthesis of antibiotics","H01146///Aminoacylase 1 deficiency","M00028///Ornithine biosynthesis, glutamate => ornithine","R00669///N2-Acetyl-L-ornithine amidohydrolase   N-Acetylornithine + H2O <=> Acetate + L-Ornithine+++R10553///N-acetyl-L-cysteine-S-conjugate amidohydrolase (carboxylate-forming)   S-Substituted N-acetyl-L-cysteine + H2O <=> S-Substituted L-cysteine + Acetate","GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0004046///aminoacylase activity+++GO:0008237///metallopeptidase activity","GO:0006520///cellular amino acid metabolic process+++GO:0006508///proteolysis","IPR002933///Peptidase M20+++IPR036264///Bacterial exopeptidase dimerisation domain+++IPR011650///Peptidase M20, dimerisation domain+++IPR010159///N-acyl-L-amino-acid amidohydrolase+++IPR001261///ArgE/DapE/ACY1/CPG2/YscS, conserved site","[A0A1B0GU64_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000489981};+++[A0A1B0GUT4_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490236};+++[A0A1B0GV31_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490353}; Flags: Fragment;+++[A0A1B0GVA5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490434}; Flags: Fragment;+++[A0A1B0GVC5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490460}; Flags: Fragment;+++[A0A1B0GVN8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490593}; Flags: Fragment;+++[A0A1B0GVQ8_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490616}; Flags: Fragment;+++[A0A1B0GVW5_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490680}; Flags: Fragment;+++[A0A1B0GW23_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490744}; Flags: Fragment;+++[A0A1B0GW28_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490750}; Flags: Fragment;+++[A0A1B0GWD9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000490887};+++[B4DNW0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60317, highly similar to Aminoacylase-1 {ECO:0000313|EMBL:BAG60372.1};+++[C9JMV9_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420487};+++[F2Z3Q0_HUMAN|Unreviewed]SubName: Full=ABHD14A-ACY1 readthrough {ECO:0000313|Ensembl:ENSP00000420395};"]
[100526767,"'RNF103-CHMP3'",0,23.31,11.655,"04217///Necroptosis+++04144///Endocytosis",null,"M00412///ESCRT-III complex",null,"GO:0031410///cytoplasmic vesicle+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0000815///ESCRT III complex+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016021///integral component of membrane+++GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0005770///late endosome+++GO:0010494///cytoplasmic stress granule+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0031902///late endosome membrane","GO:0032454///histone demethylase activity (H3-K9 specific)+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0031210///phosphatidylcholine binding+++GO:0050681///androgen receptor binding+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0003727///single-stranded RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:1990381///ubiquitin-specific protease binding+++GO:0003697///single-stranded DNA binding+++GO:0051213///dioxygenase activity+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0031490///chromatin DNA binding+++GO:0032452///histone demethylase activity","GO:0007034///vacuolar transport","IPR005024///Snf7 family","[CHMP3_HUMAN|Reviewed]RecName: Full=Charged multivesicular body protein 3; AltName: Full=Chromatin-modifying protein 3; AltName: Full=Neuroendocrine differentiation factor; AltName: Full=Vacuolar protein sorting-associated protein 24; Short=hVps24;+++[A0A140T963_HUMAN|Unreviewed]SubName: Full=RNF103-CHMP3 readthrough {ECO:0000313|Ensembl:ENSP00000392995}; Flags: Fragment;"]
[100526772,"'TMEM110-MUSTN1'",13.23,19.51,16.37,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005246///calcium channel regulator activity","GO:0042246///tissue regeneration+++GO:0035988///chondrocyte proliferation+++GO:0002062///chondrocyte differentiation","IPR022127///Store-operated calcium entry regulator STIMATE/YPL162C+++IPR031394///Musculoskeletal embryonic nuclear protein 1","[A8MSY1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422941};+++[H0Y8V1_HUMAN|Unreviewed]SubName: Full=TMEM110-MUSTN1 readthrough {ECO:0000313|Ensembl:ENSP00000422189}; Flags: Fragment;"]
[100526783,"'C15orf38-AP3S2'",428.74,327.2,377.97,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030117///membrane coat+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0051126///negative regulation of actin nucleation","IPR011012///Longin-like domain superfamily+++IPR018889///Arpin+++IPR000804///Clathrin adaptor complex, small chain+++IPR022775///AP complex, mu/sigma subunit","[A0A0A6YYH1_HUMAN|Unreviewed]SubName: Full=Protein C15orf38-AP3S2 {ECO:0000313|Ensembl:ENSP00000381377};+++[H0YL85_HUMAN|Unreviewed]SubName: Full=C15orf38-AP3S2 readthrough {ECO:0000313|Ensembl:ENSP00000453100}; Flags: Fragment;+++[H0YMK0_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588}; Flags: Fragment;"]
[100526835,"'FPGT-TNNI3K'",2.12,2.08,2.1,"00051///Fructose and mannose metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++01100///Metabolic pathways","H02125///Cardiac conduction disease with dilated cardiomyopathy",null,"R01951///GTP:beta-L-fucose-1-phosphate guanylyltransferase GTP + L-Fucose 1-phosphate <=> Diphosphate + GDP-L-fucose","GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding","GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade","IPR002110///Ankyrin repeat+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR020683///Ankyrin repeat-containing domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR017441///Protein kinase, ATP binding site+++IPR036770///Ankyrin repeat-containing domain superfamily","[TNI3K_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase TNNI3K; EC=2.7.11.1; AltName: Full=Cardiac ankyrin repeat kinase; AltName: Full=Cardiac troponin I-interacting kinase; AltName: Full=TNNI3-interacting kinase;+++[A6NHC7_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000359930};+++[E9PKE1_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000433587}; Flags: Fragment;+++[V9GXZ4_HUMAN|Unreviewed]SubName: Full=FPGT-TNNI3K readthrough {ECO:0000313|Ensembl:ENSP00000450895};"]
[100526842,"'RPL17-C18orf32'",91.8,59.99,75.895,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0002181///cytoplasmic translation","IPR001063///Ribosomal protein L22/L17+++IPR005721///Ribosomal protein L22/L17, eukaryotic/archaeal+++IPR036394///Ribosomal protein L22/L17 superfamily+++IPR018260///Ribosomal protein L22/L17, conserved site","[A0A0A0MRF8_HUMAN|Unreviewed]SubName: Full=RPL17-C18orf32 readthrough {ECO:0000313|Ensembl:ENSP00000352143};+++[A0A0A6YYL6_HUMAN|Unreviewed]SubName: Full=Protein RPL17-C18orf32 {ECO:0000313|Ensembl:ENSP00000463379};"]
[100527943,"'TGIF2-RAB5IF'",15.4,4.4,9.9,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","IPR009057///Homeobox-like domain superfamily+++IPR010742///Rab5-interacting protein+++IPR029008///Rab5-interacting protein family+++IPR001356///Homeobox domain+++IPR008422///Homeobox KN domain","[A0A0A6YYL0_HUMAN|Unreviewed]SubName: Full=Protein TGIF2-C20orf24 {ECO:0000313|Ensembl:ENSP00000454021};"]
[100527963,"'PMF1-BGLAP'",79.84,48.63,64.235,"04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0000818///nuclear MIS12/MIND complex+++GO:0005829///cytosol+++GO:0005667///transcription factor complex+++GO:0000444///MIS12/MIND type complex+++GO:0005794///Golgi apparatus+++GO:0005694///chromosome+++GO:0000777///condensed chromosome kinetochore+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region","GO:0043522///leucine zipper domain binding+++GO:0003713///transcription coactivator activity+++GO:0005515///protein binding","GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006366///transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation","IPR007128///Nuclear MIS12/MIND complex subunit PMF1/Nnf1","[PMF1_HUMAN|Reviewed]RecName: Full=Polyamine-modulated factor 1; Short=PMF-1;+++[A0A087WT04_HUMAN|Unreviewed]SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000458021};+++[U3KQ54_HUMAN|Unreviewed]SubName: Full=HCG2044777 {ECO:0000313|EMBL:EAW52985.1}; SubName: Full=PMF1-BGLAP readthrough {ECO:0000313|Ensembl:ENSP00000475561};+++[V9GYH6_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476760}; Flags: Fragment;+++[V9GYI0_HUMAN|Unreviewed]SubName: Full=Polyamine-modulated factor 1 {ECO:0000313|Ensembl:ENSP00000476770};"]
[100527978,"'TMEM56-RWDD3'",8.35,3.79,6.07,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0033235///positive regulation of protein sumoylation+++GO:1902073///positive regulation of hypoxia-inducible factor-1alpha signaling pathway+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","IPR006634///TRAM/LAG1/CLN8 homology domain","[S4R3V7_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000474793}; Flags: Fragment;+++[S4R434_HUMAN|Unreviewed]SubName: Full=TMEM56-RWDD3 readthrough {ECO:0000313|Ensembl:ENSP00000475025};"]
[100528020,"'FAM187A'",5,4,4.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain+++IPR039311///FAM187A/B+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013106///Immunoglobulin V-set domain","[F187A_HUMAN|Reviewed]RecName: Full=Ig-like V-type domain-containing protein FAM187A; Flags: Precursor;"]
[100528030,"'POC1B-GALNT4'",0,10.98,5.49,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0006486///protein glycosylation","IPR001173///Glycosyltransferase 2-like+++IPR000772///Ricin B, lectin domain+++IPR029044///Nucleotide-diphospho-sugar transferases+++IPR035992///Ricin B-like lectins","[GALT4_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 4; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 4; Short=GalNAc-T4; Short=pp-GaNTase 4; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 4; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4;+++[F8VUJ3_HUMAN|Unreviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242}; EC=2.4.1.- {ECO:0000256|RuleBase:RU361242}; AltName: Full=Protein-UDP acetylgalactosaminyltransferase {ECO:0000256|RuleBase:RU361242};+++[F8VZB3_HUMAN|Unreviewed]SubName: Full=POC1B-GALNT4 readthrough {ECO:0000313|Ensembl:ENSP00000447754};"]
[100528062,"'ARMCX5-GPRASP2'",41.97,57.28,49.625,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0003697///single-stranded DNA binding+++GO:0001540///amyloid-beta binding+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity","GO:0050769///positive regulation of neurogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:1990172///G protein-coupled receptor catabolic process+++GO:0007611///learning or memory+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0006351///transcription, DNA-templated+++GO:0032197///transposition, RNA-mediated+++GO:0008333///endosome to lysosome transport+++GO:0051965///positive regulation of synapse assembly","IPR006911///Armadillo repeat-containing domain+++IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical","[GASP2_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 2; Short=GASP-2;"]
[100528064,"'NEDD8-MDP1'",5.66,3.2,4.43,"04144///Endocytosis+++04217///Necroptosis","H01202///Cataract","M00412///ESCRT-III complex",null,"GO:0030659///cytoplasmic vesicle membrane+++GO:0031902///late endosome membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0000815///ESCRT III complex+++GO:0030496///midbody+++GO:0030117///membrane coat+++GO:0005737///cytoplasm","GO:0016791///phosphatase activity","GO:0016311///dephosphorylation","IPR036412///HAD-like superfamily+++IPR019956///Ubiquitin+++IPR010036///Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type+++IPR010033///HAD-superfamily phosphatase, subfamily IIIC+++IPR005024///Snf7 family+++IPR038738///Nedd8-like ubiquitin+++IPR019954///Ubiquitin conserved site+++IPR035679///Magnesium-dependent phosphatase-1, eukaryotic-type+++IPR000626///Ubiquitin domain+++IPR031751///Protein of unknown function DUF4735+++IPR023214///HAD superfamily+++IPR029071///Ubiquitin-like domain superfamily","[E9PL57_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000431482}; Flags: Fragment;+++[E9PS38_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000432117};+++[S4R3E9_HUMAN|Unreviewed]SubName: Full=NEDD8-MDP1 readthrough {ECO:0000313|Ensembl:ENSP00000474249};"]
[100529063,"'BCL2L2-PABPN1'",32.21,0,16.105,"03015///mRNA surveillance pathway+++05164///Influenza A","H00704///Oculopharyngeal muscular dystrophy (OPMD)",null,null,"GO:0005774///vacuolar membrane+++GO:0042405///nuclear inclusion body+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0031301///integral component of organelle membrane+++GO:0016607///nuclear speck+++GO:0005887///integral component of plasma membrane+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0097136///Bcl-2 family protein complex","GO:0097718///disordered domain specific binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0070063///RNA polymerase binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043621///protein self-association+++GO:0051400///BH domain binding+++GO:0046982///protein heterodimerization activity+++GO:0042803///protein homodimerization activity","GO:0031124///mRNA 3'-end processing+++GO:0015891///siderophore transport+++GO:0060011///Sertoli cell proliferation+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0006396///RNA processing+++GO:1904247///positive regulation of polynucleotide adenylyltransferase activity+++GO:0007283///spermatogenesis+++GO:0055072///iron ion homeostasis+++GO:0043066///negative regulation of apoptotic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006936///muscle contraction+++GO:0006397///mRNA processing+++GO:0006369///termination of RNA polymerase II transcription+++GO:0000165///MAPK cascade+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0046778///modification by virus of host mRNA processing+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage","IPR036834///Blc2-like superfamily+++IPR020731///Apoptosis regulator, Bcl-2, BH4 motif, conserved site+++IPR020726///Apoptosis regulator, Bcl-2, BH2 motif, conserved site+++IPR026298///Blc2 family+++IPR005828///Major facilitator,  sugar transporter-like+++IPR035979///RNA-binding domain superfamily+++IPR013280///Apoptosis regulator, Bcl-W+++IPR003093///Apoptosis regulator, Bcl-2 protein, BH4+++IPR000504///RNA recognition motif domain+++IPR034911///Polyadenylate-binding protein 2+++IPR036259///MFS transporter superfamily+++IPR005829///Sugar transporter, conserved site+++IPR020846///Major facilitator superfamily domain+++IPR020717///Apoptosis regulator, Bcl-2, BH1 motif, conserved site+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR002475///Bcl2-like","[AR1_XENLA|diamond]RecName: Full=Apoptosis regulator R1; AltName: Full=XR1; Flags: Fragment;+++[B2CL2_BOVIN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_CANLF|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_HUMAN|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W;+++[B2CL2_MOUSE|diamond]RecName: Full=Bcl-2-like protein 2; Short=Bcl2-L-2; AltName: Full=Apoptosis regulator Bcl-W; AltName: Full=c98;+++[PAB2A_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-A; Short=PABP-2-A; Short=Poly(A)-binding protein 2-A; AltName: Full=Nuclear poly(A)-binding protein 1-A; AltName: Full=Poly(A)-binding protein II-A; Short=PABII-A; AltName: Full=Polyadenylate-binding nuclear protein 1-A; AltName: Full=XLnPABP2-A; AltName: Full=nPABP2-A; AltName: Full=xPABPII-A;+++[PAB2B_XENLA|diamond]RecName: Full=Polyadenylate-binding protein 2-B; Short=PABP-2-B; Short=Poly(A)-binding protein 2-B; AltName: Full=Nuclear poly(A)-binding protein 1-B; AltName: Full=Poly(A)-binding protein II-B; Short=PABII-B; AltName: Full=Polyadenylate-binding nuclear protein 1-B; AltName: Full=XLnPABP2-B; AltName: Full=nPABP2-B; AltName: Full=xPABPII-B;+++[PABP2_BOVIN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_HUMAN|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_MOUSE|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[PABP2_XENTR|diamond]RecName: Full=Polyadenylate-binding protein 2; Short=PABP-2; Short=Poly(A)-binding protein 2; AltName: Full=Nuclear poly(A)-binding protein 1; AltName: Full=Poly(A)-binding protein II; Short=PABII; AltName: Full=Polyadenylate-binding nuclear protein 1;+++[S22AH_BOVIN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Lipocalin-2 receptor;+++[S22AH_HUMAN|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor; AltName: Full=Neutrophil gelatinase-associated lipocalin receptor; Short=NgalR;+++[S22AH_MOUSE|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AH_RAT|diamond]RecName: Full=Solute carrier family 22 member 17; AltName: Full=24p3 receptor; Short=24p3R; AltName: Full=Brain-type organic cation transporter; AltName: Full=Lipocalin-2 receptor;+++[S22AV_HUMAN|diamond]RecName: Full=Putative solute carrier family 22 member 31 {ECO:0000305};"]
[100529097,"'RPL36A-HNRNPH2'",696.66,645.11,670.885,"03010///Ribosome","H00658///Syndromic X-linked mental retardation+++H00125///Fabry disease","M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes","R01329///Epimelibiose galactohydrolase Epimelibiose + H2O <=> D-Mannose + D-Galactose+++R03634///Stachyose + H2O <=> Raffinose + D-Galactose+++R05961///H2O + Globotriaosylceramide <=> D-Galactose + Lactosylceramide+++R01194///3-O-alpha-D-Galactosyl-1D-myo-inositol galactohydrolase; 1-alpha-D-Galactosyl-myo-inositol alpha-D-Galactosyl-(1->3)-1D-myo-inositol + H2O <=> myo-Inositol + D-Galactose+++R04019///Digalactosylceramide galactohydrolase Digalactosylceramide + H2O <=> Galactosylceramide + D-Galactose+++R04470///Digalactosyl-diacylglycerol galactohydrolase Digalactosyl-diacylglycerol + H2O <=> 1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol + D-Galactose+++R05549///D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose + H2O <=> D-Galactose + Melibiose+++R06091///Melibiose + H2O <=> D-Galactose + D-Glucose+++R01104///Galactosylglycerol galactohydrolase 3-beta-D-Galactosyl-sn-glycerol + H2O <=> D-Galactose + Glycerol+++R01101///melibiose galactohydrolase Melibiose + H2O <=> D-Galactose + D-Glucose+++R02926///Melibiitol galactohydrolase Melibiitol + H2O <=> D-Sorbitol + D-Galactose+++R01103///Raffinose galactohydrolase Raffinose + H2O <=> D-Galactose + Sucrose","GO:0005840///ribosome+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005783///endoplasmic reticulum","GO:0003735///structural constituent of ribosome","GO:0006412///translation","IPR000552///Ribosomal protein L44e+++IPR012996///Zinc finger, CHHC-type+++IPR011332///Zinc-binding ribosomal protein+++IPR000504///RNA recognition motif domain+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[H0Y3V9_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386974};+++[H7BZ11_HUMAN|Unreviewed]SubName: Full=RPL36A-HNRNPH2 readthrough {ECO:0000313|Ensembl:ENSP00000386655};"]
[100529144,"'CORO7-PAM16'",50.78,19.83,35.305,null,"H01830///Spondylometaphyseal dysplasia, Megarbane-Dagher-Melki type (SMDMDM)",null,null,"GO:0005794///Golgi apparatus","GO:0003779///actin binding","GO:0001503///ossification+++GO:0030150///protein import into mitochondrial matrix+++GO:0032780///negative regulation of ATPase activity+++GO:0030041///actin filament polymerization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","IPR001680///WD40 repeat+++IPR019775///WD40 repeat, conserved site+++IPR027331///Coronin 7+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015505///Coronin+++IPR036869///Chaperone J-domain superfamily+++IPR017986///WD40-repeat-containing domain+++IPR015048///Domain of unknown function DUF1899+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[A0A0A6YYL4_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};+++[I3L167_HUMAN|Unreviewed]RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};"]
[100529215,"'ZNF559-ZNF177'",12.54,0,6.27,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated","IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily","[ZN177_HUMAN|Reviewed]RecName: Full=Zinc finger protein 177;+++[S4R342_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473911};+++[S4R365_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473968};+++[S4R367_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000473974}; Flags: Fragment;+++[S4R3A1_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474076};+++[S4R3B1_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474108}; Flags: Fragment;+++[S4R3H7_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474354};+++[S4R3Q2_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474602}; Flags: Fragment;+++[S4R3T9_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474716}; Flags: Fragment;+++[S4R401_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474918}; Flags: Fragment;+++[S4R422_HUMAN|Unreviewed]SubName: Full=ZNF559-ZNF177 readthrough {ECO:0000313|Ensembl:ENSP00000474980};"]
[100529239,"'RPS10-NUDT3'",0,9.68,4.84,"03010///Ribosome","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0022627///cytosolic small ribosomal subunit+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0003735///structural constituent of ribosome","GO:0000028///ribosomal small subunit assembly","IPR015797///NUDIX hydrolase-like domain superfamily+++IPR020084///NUDIX hydrolase, conserved site+++IPR037447///40S Ribosomal protein S10+++IPR005326///Plectin/S10, N-terminal+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR000086///NUDIX hydrolase domain","[A0A1W2PQS6_HUMAN|Unreviewed]SubName: Full=RPS10-NUDT3 readthrough {ECO:0000313|Ensembl:ENSP00000491891};+++[A0A2R8Y6L3_HUMAN|Unreviewed]SubName: Full=RPS10-NUDT3 readthrough {ECO:0000313|Ensembl:ENSP00000495405}; Flags: Fragment;+++[S4R435_HUMAN|Unreviewed]SubName: Full=RPS10-NUDT3 readthrough {ECO:0000313|Ensembl:ENSP00000475027}; Flags: Fragment;"]
[100529240,"'ZNF816-ZNF321P'",11.74,10.45,11.095,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box","[ZN321_HUMAN|Reviewed]RecName: Full=Putative protein ZNF321; AltName: Full=Zinc finger protein 321 pseudogene;+++[A0A0X1KG74_HUMAN|Unreviewed]SubName: Full=ZNF816-ZNF321P readthrough {ECO:0000313|Ensembl:ENSP00000375656};"]
[100529251,"'CKLF-CMTM1'",0,1.22,0.61,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005125///cytokine activity","GO:0006935///chemotaxis","IPR008253///Marvel domain","[A0A087WVB3_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000479319};+++[A0A087X286_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000484781};+++[E9PIV8_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433857};+++[E9PLU7_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000435007}; SubName: Full=Chemokine-like factor {ECO:0000313|Ensembl:ENSP00000431270};+++[E9PSG2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433998};+++[H0YDF2_HUMAN|Unreviewed]SubName: Full=CKLF-CMTM1 readthrough {ECO:0000313|Ensembl:ENSP00000433503}; Flags: Fragment;"]
[10053,"'AP1M2'",10,12,11,"04142///Lysosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000139///Golgi membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0030131///clathrin adaptor complex+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006605///protein targeting+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0050690///regulation of defense response to virus by virus+++GO:0006886///intracellular protein transport+++GO:0006903///vesicle targeting+++GO:0015031///protein transport","IPR028565///Mu homology domain+++IPR001392///Clathrin adaptor, mu subunit+++IPR036168///AP-2 complex subunit mu, C-terminal superfamily+++IPR022775///AP complex, mu/sigma subunit+++IPR011012///Longin-like domain superfamily+++IPR018240///Clathrin adaptor, mu subunit, conserved site","[AP1M2_HUMAN|Reviewed]RecName: Full=AP-1 complex subunit mu-2; AltName: Full=AP-mu chain family member mu1B; AltName: Full=Adaptor protein complex AP-1 subunit mu-2; AltName: Full=Adaptor-related protein complex 1 subunit mu-2; AltName: Full=Clathrin assembly protein complex 1 mu-2 medium chain 2; AltName: Full=Golgi adaptor HA1/AP1 adaptin mu-2 subunit; AltName: Full=Mu-adaptin 2; AltName: Full=Mu1B-adaptin;+++[K7EJJ1_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465193}; Flags: Fragment;+++[K7EK69_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465488}; Flags: Fragment;+++[K7EL08_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000465865}; Flags: Fragment;+++[K7EMG5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000466494}; Flags: Fragment;+++[K7EPI9_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467406};+++[K7EPR4_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000467498}; Flags: Fragment;+++[K7ERH5_HUMAN|Unreviewed]SubName: Full=AP-1 complex subunit mu-2 {ECO:0000313|Ensembl:ENSP00000468260}; Flags: Fragment;+++[Q53GI5_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 1, mu 2 subunit variant {ECO:0000313|EMBL:BAD96666.1}; Flags: Fragment;"]
[100532726,"'NDUFC2-KCTD14'",58.14,55.84,56.99,"00190///Oxidative phosphorylation+++01100///Metabolic pathways+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04714///Thermogenesis+++05010///Alzheimer's disease+++05016///Huntington's disease+++04723///Retrograde endocannabinoid signaling","H00810///Progressive myoclonic epilepsy (PME/ EPM)","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0070469///respiratory chain+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane","GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0055114///oxidation-reduction process+++GO:0006120///mitochondrial electron transport, NADH to ubiquinone","IPR009423///NADH:ubiquinone oxidoreductase, subunit b14.5b","[NDUCR_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2; AltName: Full=NDUFC2-KCTD14 readthrough transcript protein;+++[A0A087WUM3_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000478766};+++[A0A087WY27_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000481472};+++[E9PRQ4_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 subunit C2, isoform 2 {ECO:0000313|Ensembl:ENSP00000435967};"]
[100532731,"'COMMD3-BMI1'",145.03,218.36,181.695,"05206///MicroRNAs in cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05202///Transcriptional misregulation in cancer","H00025///Penile cancer",null,null,"GO:0016604///nuclear body+++GO:0035102///PRC1 complex+++GO:0005829///cytosol","GO:1990841///promoter-specific chromatin binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0036353///histone H2A-K119 monoubiquitination+++GO:0006342///chromatin silencing+++GO:0006814///sodium ion transport","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR039642///E3 ubiquitin-protein ligase/polycomb group RING finger protein+++IPR017907///Zinc finger, RING-type, conserved site+++IPR001841///Zinc finger, RING-type+++IPR032443///RAWUL domain","[BMI1_HUMAN|Reviewed]RecName: Full=Polycomb complex protein BMI-1; AltName: Full=Polycomb group RING finger protein 4; AltName: Full=RING finger protein 51;+++[Q5T8Z1_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000398759}; Flags: Fragment;+++[R4GMW6_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473382}; Flags: Fragment;+++[R4GMX3_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473391};+++[R4GN54_HUMAN|Unreviewed]SubName: Full=COMMD3-BMI1 readthrough {ECO:0000313|Ensembl:ENSP00000473495}; Flags: Fragment;"]
[100532736,"'MINOS1-NBL1'",0,4.02,2.01,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005743///mitochondrial inner membrane+++GO:0061617///MICOS complex+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0036122///BMP binding+++GO:0016015///morphogen activity+++GO:0042803///protein homodimerization activity","GO:0030514///negative regulation of BMP signaling pathway+++GO:0090027///negative regulation of monocyte chemotaxis+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0038098///sequestering of BMP from receptor via BMP binding+++GO:0048263///determination of dorsal identity+++GO:0048812///neuron projection morphogenesis+++GO:0045666///positive regulation of neuron differentiation+++GO:0007399///nervous system development","IPR006207///Cystine knot, C-terminal+++IPR029034///Cystine-knot cytokine+++IPR016728///Neuroblastoma suppressor of tumourigenicity 1+++IPR004133///DAN","[NBL1_HUMAN|Reviewed]RecName: Full=Neuroblastoma suppressor of tumorigenicity 1; AltName: Full=DAN domain family member 1; AltName: Full=Protein N03; AltName: Full=Zinc finger protein DAN; Flags: Precursor;+++[R4GMM1_HUMAN|Unreviewed]SubName: Full=MINOS1-NBL1 readthrough {ECO:0000313|Ensembl:ENSP00000473256}; Flags: Fragment;+++[R4GMY4_HUMAN|Unreviewed]RecName: Full=MICOS complex subunit MIC10 {ECO:0000256|RuleBase:RU363011};+++[R4GNA1_HUMAN|Unreviewed]RecName: Full=MICOS complex subunit MIC10 {ECO:0000256|RuleBase:RU363011}; Flags: Fragment;"]
[100533105,"'C8orf44-SGK3'",0,41.21,20.605,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0055037///recycling endosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0005737///cytoplasm+++GO:0005795///Golgi stack+++GO:0005654///nucleoplasm+++GO:0005769///early endosome","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0035091///phosphatidylinositol binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity","GO:0016567///protein ubiquitination+++GO:0035871///protein K11-linked deubiquitination+++GO:0071108///protein K48-linked deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0016320///endoplasmic reticulum membrane fusion+++GO:0090168///Golgi reassembly","IPR036871///PX domain superfamily+++IPR017892///Protein kinase, C-terminal+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR037900///CISK, PX domain+++IPR037709///Serine/threonine-protein kinase Sgk3, catalytic domain+++IPR000961///AGC-kinase, C-terminal+++IPR008271///Serine/threonine-protein kinase, active site+++IPR000719///Protein kinase domain+++IPR001683///Phox homologous domain","[SGK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk3; EC=2.7.11.1; AltName: Full=Cytokine-independent survival kinase; AltName: Full=Serum/glucocorticoid-regulated kinase 3; AltName: Full=Serum/glucocorticoid-regulated kinase-like;+++[A0A024R807_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};"]
[100533106,"'ZHX1-C8orf76'",4.45,3.75,4.1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0006351///transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR011990///Tetratricopeptide-like helical domain superfamily","[ZHX1R_HUMAN|Reviewed]RecName: Full=Zinc fingers and homeoboxes protein 1, isoform 2; AltName: Full=ZHX1-C8orf76 readthrough transcript protein;+++[A0A0X1KG80_HUMAN|Unreviewed]SubName: Full=Zinc fingers and homeoboxes protein 1, isoform 2 {ECO:0000313|Ensembl:ENSP00000481928}; Flags: Fragment;"]
[100533178,"'PRORY'",3,7,5,{"$nulls":7},"IPR013544///Domain of unknown function DUF1725","[PRORY_HUMAN|Reviewed]RecName: Full=Proline-rich protein, Y-linked;"]
[100533183,"'ZNF664-RFLNA'",29.18,19.07,24.125,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0061181///regulation of chondrocyte development+++GO:0061572///actin filament bundle organization","IPR028215///Refilin family","[RFLA_HUMAN|Reviewed]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;"]
[100533467,"'BIVM-ERCC5'",339.83,299.75,319.79,"03420///Nucleotide excision repair","H00403///Disorders of nucleotide excision repair+++H01428///Xeroderma pigmentosum (XP)",null,null,"GO:0005634///nucleus","GO:0003697///single-stranded DNA binding+++GO:0004518///nuclease activity+++GO:0003677///DNA binding+++GO:0003824///catalytic activity+++GO:0004520///endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds","GO:0006281///DNA repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006295///nucleotide-excision repair, DNA incision, 3'-to lesion+++GO:0006289///nucleotide-excision repair","IPR008918///Helix-hairpin-helix motif, class 2+++IPR006084///XPG/Rad2 endonuclease+++IPR006085///XPG N-terminal+++IPR036279///5'-3' exonuclease, C-terminal domain superfamily+++IPR019974///XPG conserved site+++IPR006086///XPG-I domain+++IPR001044///XPG/Rad2 endonuclease, eukaryotes+++IPR029060///PIN-like domain superfamily","[A0A1W2PRR4_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492455}; Flags: Fragment;+++[A0A1W2PRU8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492444}; Flags: Fragment;+++[A0A1W2PS85_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000492684};+++[Q59FZ7_HUMAN|Unreviewed]SubName: Full=DNA-repair protein complementing XP-G cells variant {ECO:0000313|EMBL:BAD92549.1}; Flags: Fragment;+++[R4GMW8_HUMAN|Unreviewed]SubName: Full=BIVM-ERCC5 readthrough {ECO:0000313|Ensembl:ENSP00000491742}; SubName: Full=DNA repair protein-complementing XP-G cells {ECO:0000313|Ensembl:ENSP00000473384}; SubName: Full=ERCC5-202 protein {ECO:0000313|EMBL:CDY80175.1};"]
[100533496,"'TVP23C-CDRT4'",80.12,118.52,99.32,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009306///protein secretion+++GO:0016192///vesicle-mediated transport","IPR008564///Golgi apparatus membrane protein TVP23-like","[TV23C_HUMAN|Reviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog C;+++[A0A0A6YYB9_HUMAN|Unreviewed]RecName: Full=Golgi apparatus membrane protein TVP23 homolog {ECO:0000256|RuleBase:RU361206};+++[E5RGC5_HUMAN|Unreviewed]SubName: Full=Golgi apparatus membrane protein TVP23 homolog C {ECO:0000313|Ensembl:ENSP00000428748}; SubName: Full=TVP23C-CDRT4 readthrough {ECO:0000313|Ensembl:ENSP00000430143};"]
[100533952,"'RBAK-RBAKDN'",1.27,4.36,2.815,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box","[A0A0A6YYG8_HUMAN|Unreviewed]SubName: Full=Protein RBAK-RBAKDN {ECO:0000313|Ensembl:ENSP00000380112};+++[I3L0D1_HUMAN|Unreviewed]SubName: Full=HCG1647537, isoform CRA_b {ECO:0000313|EMBL:EAW87320.1}; SubName: Full=RBAK-RBAKDN readthrough {ECO:0000313|Ensembl:ENSP00000385560};"]
[100534012,"'TNFAIP8L2-SCNM1'",46.45,0,23.225,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0019899///enzyme binding+++GO:0046872///metal ion binding","GO:0042981///regulation of apoptotic process+++GO:0050868///negative regulation of T cell activation+++GO:0050728///negative regulation of inflammatory response+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0045087///innate immune response","IPR031622///Sodium channel modifier 1, zinc-finger+++IPR033570///Sodium channel modifier 1+++IPR031625///Sodium channel modifier 1, acidic C-terminal domain","[SCNM1_HUMAN|Reviewed]RecName: Full=Sodium channel modifier 1;"]
[100534599,"'ISY1-RAB43'",530.02,328.66,429.34,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005634///nucleus+++GO:0005768///endosome+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0000974///Prp19 complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0071014///post-mRNA release spliceosomal complex+++GO:0032588///trans-Golgi network membrane+++GO:0071012///catalytic step 1 spliceosome+++GO:0071020///post-spliceosomal complex+++GO:0030670///phagocytic vesicle membrane+++GO:0045335///phagocytic vesicle+++GO:0070062///extracellular exosome","GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008270///zinc ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005525///GTP binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003924///GTPase activity+++GO:0046872///metal ion binding","GO:0000350///generation of catalytic spliceosome for second transesterification step","IPR009360///Pre-mRNA-splicing factor Isy1+++IPR037200///Pre-mRNA-splicing factor Isy1 superfamily+++IPR029012///Helix hairpin bin domain superfamily","[ISY1_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ISY1 homolog;+++[H9XFA1_HUMAN|Unreviewed]SubName: Full=ISY1-RAB43 {ECO:0000313|EMBL:AFG72967.1}; Flags: Fragment;"]
[10054,"'UBA2'",466,447,456.5,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0031510///SUMO activating enzyme complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0005524///ATP binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0016881///acid-amino acid ligase activity+++GO:0000166///nucleotide binding+++GO:0008047///enzyme activator activity+++GO:0019948///SUMO activating enzyme activity+++GO:0000287///magnesium ion binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0044388///small protein activating enzyme binding+++GO:0044390///ubiquitin-like protein conjugating enzyme binding+++GO:0043565///sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0044241///lipid digestion+++GO:0072148///epithelial cell fate commitment+++GO:0007411///axon guidance+++GO:0021800///cerebral cortex tangential migration+++GO:0030154///cell differentiation+++GO:0001764///neuron migration+++GO:0021846///cell proliferation in forebrain+++GO:0007275///multicellular organism development+++GO:0046622///positive regulation of organ growth+++GO:0043085///positive regulation of catalytic activity+++GO:0021772///olfactory bulb development+++GO:0030900///forebrain development+++GO:0010628///positive regulation of gene expression+++GO:0021759///globus pallidus development+++GO:0016925///protein sumoylation+++GO:0007399///nervous system development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0021831///embryonic olfactory bulb interneuron precursor migration+++GO:0006355///regulation of transcription, DNA-templated","IPR032426///SUMO-activating enzyme subunit 2, C-terminal domain+++IPR035985///Ubiquitin-activating enzyme+++IPR033127///Ubiquitin-activating enzyme E1, Cys active site+++IPR023318///Ubiquitin activating enzyme, alpha domain superfamily+++IPR028077///Ubiquitin/SUMO-activating enzyme ubiquitin-like domain+++IPR030661///SUMO-activating enzyme subunit Uba2+++IPR018074///Ubiquitin-activating enzyme E1, conserved site+++IPR000594///THIF-type NAD/FAD binding fold","[SAE2_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 2; EC=2.3.2.-; AltName: Full=Anthracycline-associated resistance ARX; AltName: Full=Ubiquitin-like 1-activating enzyme E1B; AltName: Full=Ubiquitin-like modifier-activating enzyme 2;+++[K7EPL2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000467433}; Flags: Fragment;+++[K7ES38_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468538};+++[K7ESK7_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000468756}; Flags: Fragment;+++[U3KQ55_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475565};+++[U3KQ93_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 2 {ECO:0000313|Ensembl:ENSP00000475656};"]
[10055,"'SAE1'",1380,1074,1227,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005634///nucleus+++GO:0031510///SUMO activating enzyme complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019948///SUMO activating enzyme activity+++GO:0043008///ATP-dependent protein binding+++GO:0044388///small protein activating enzyme binding+++GO:0008047///enzyme activator activity+++GO:0016874///ligase activity+++GO:0046982///protein heterodimerization activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0008022///protein C-terminus binding+++GO:0004839///ubiquitin activating enzyme activity","GO:0006464///cellular protein modification process+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0016567///protein ubiquitination+++GO:0016925///protein sumoylation+++GO:0043085///positive regulation of catalytic activity","IPR000594///THIF-type NAD/FAD binding fold+++IPR035985///Ubiquitin-activating enzyme+++IPR000011///Ubiquitin/SUMO-activating enzyme E1","[SAE1_HUMAN|Reviewed]RecName: Full=SUMO-activating enzyme subunit 1; AltName: Full=Ubiquitin-like 1-activating enzyme E1A; Contains: RecName: Full=SUMO-activating enzyme subunit 1, N-terminally processed;+++[A0A024R0R4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_b {ECO:0000313|EMBL:EAW57462.1};+++[B3KNJ4_HUMAN|Unreviewed]SubName: Full=SUMO-1 activating enzyme subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW57460.1}; SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000398818}; SubName: Full=cDNA FLJ14689 fis, clone NT2RP2005204, highly similar to Ubiquitin-like 1-activating enzyme E1A {ECO:0000313|EMBL:BAG51356.1};+++[M0QX65_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000468931}; Flags: Fragment;+++[M0QYM8_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469938}; Flags: Fragment;+++[M0QYP2_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000469978}; Flags: Fragment;+++[M0QZS6_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000470741};+++[M0R054_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000471010}; Flags: Fragment;+++[M0R286_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000472389}; Flags: Fragment;+++[M0R375_HUMAN|Unreviewed]SubName: Full=SUMO-activating enzyme subunit 1 {ECO:0000313|Ensembl:ENSP00000473037};"]
[10056,"'FARSB'",557,550,553.5,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0016020///membrane+++GO:0009328///phenylalanine-tRNA ligase complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding+++GO:0004826///phenylalanine-tRNA ligase activity","GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0006412///translation+++GO:0051290///protein heterotetramerization","IPR004531///Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic+++IPR009061///Putative DNA-binding domain superfamily+++IPR005147///tRNA synthetase, B5-domain+++IPR020825///Phenylalanyl-tRNA synthetase, B3/B4+++IPR005146///B3/B4 tRNA-binding domain","[SYFB_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase beta subunit; EC=6.1.1.20 {ECO:0000269|PubMed:20223217}; AltName: Full=Phenylalanyl-tRNA synthetase beta subunit; Short=PheRS;+++[Q9BR63_HUMAN|Unreviewed]SubName: Full=FARSB protein {ECO:0000313|EMBL:AAH06502.2}; Flags: Fragment;"]
[10057,"'ABCC5'",859,1142,1000.5,"01523///Antifolate resistance+++02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0008514///organic anion transmembrane transporter activity+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity","GO:0015711///organic anion transport+++GO:0055085///transmembrane transport+++GO:0030213///hyaluronan biosynthetic process+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport","IPR003593///AAA+ ATPase domain+++IPR011527///ABC transporter type 1, transmembrane domain+++IPR030238///Multidrug resistance-associated protein 5+++IPR003439///ABC transporter-like+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR017871///ABC transporter, conserved site+++IPR036640///ABC transporter type 1, transmembrane domain superfamily","[MRP5_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 5; AltName: Full=ATP-binding cassette sub-family C member 5; AltName: Full=Multi-specific organic anion transporter C; Short=MOAT-C; AltName: Full=SMRP; AltName: Full=pABC11;+++[A5PKY6_HUMAN|Unreviewed]SubName: Full=ABCC5 protein {ECO:0000313|EMBL:AAI42671.1}; SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404809};+++[C9JZL5_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000399726}; Flags: Fragment;+++[E9PET4_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000390911};+++[F8WCY8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000403510};+++[F8WDH3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000409913};+++[H7C271_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 5 {ECO:0000313|Ensembl:ENSP00000404302}; Flags: Fragment;"]
[10058,"'ABCB6'",127,138,132.5,"02010///ABC transporters","H00232///Hereditary stomatocytosis (HSt)+++H01027///Anophthalmia and microphthalmia (A/M)+++H02001///Familial pseudohyperkalemia",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005740///mitochondrial envelope+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0005741///mitochondrial outer membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005739///mitochondrion+++GO:0031307///integral component of mitochondrial outer membrane","GO:0015232///heme transporter activity+++GO:0020037///heme binding+++GO:0000166///nucleotide binding+++GO:0015562///efflux transmembrane transporter activity+++GO:0015439///heme-transporting ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0005524///ATP binding+++GO:0016887///ATPase activity","GO:0015886///heme transport+++GO:0006879///cellular iron ion homeostasis+++GO:0007420///brain development+++GO:0055085///transmembrane transport+++GO:0043588///skin development+++GO:0006779///porphyrin-containing compound biosynthetic process","IPR039421///Type I protein exporter+++IPR036640///ABC transporter type 1, transmembrane domain superfamily+++IPR032410///Mitochondrial ABC-transporter, N-terminal five TM domain+++IPR011527///ABC transporter type 1, transmembrane domain+++IPR017871///ABC transporter, conserved site+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR030255///ATP-binding cassette subfamily B member 6+++IPR003593///AAA+ ATPase domain+++IPR003439///ABC transporter-like","[ABCB6_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family B member 6, mitochondrial; AltName: Full=Mitochondrial ABC transporter 3; Short=Mt-ABC transporter 3; AltName: Full=P-glycoprotein-related protein; AltName: Full=Ubiquitously-expressed mammalian ABC half transporter;+++[A0A024R436_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6, isoform CRA_f {ECO:0000313|EMBL:EAW70701.1};+++[A0A1D9ITY9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6 {ECO:0000313|EMBL:AOZ15555.1}; Flags: Fragment;+++[H7BXK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000295750}; Flags: Fragment;+++[H7C049_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000392988}; Flags: Fragment;+++[H7C1R6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000401811}; Flags: Fragment;+++[H7C245_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000404006}; Flags: Fragment;+++[H7C3Z0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family B member 6, mitochondrial {ECO:0000313|Ensembl:ENSP00000414646}; Flags: Fragment;+++[U3TD89_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91502.1}; Flags: Fragment;+++[U3TGG4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91501.2}; Flags: Fragment;+++[U3THN0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91500.2};+++[U3THP2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91503.1}; Flags: Fragment;+++[U3TJJ6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91499.1}; Flags: Fragment;+++[U3TJK0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family B (MDR/TAP), member 6 {ECO:0000313|EMBL:BAN91504.1}; Flags: Fragment;"]
[10059,"'DNM1L'",798.46,871.55,835.005,"04214///Apoptosis - fly+++04217///Necroptosis+++04668///TNF signaling pathway+++04621///NOD-like receptor signaling pathway+++04139///Mitophagy - yeast","H01900///Encephalopathy due to defective mitochondrial and peroxisomal fission","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R02918///L-Tyrosine:tRNA(Tyr) ligase (AMP-forming) ATP + L-Tyrosine + tRNA(Tyr) <=> AMP + Diphosphate + L-Tyrosyl-tRNA(Tyr)","GO:0045202///synapse+++GO:0099073///mitochondrion-derived vesicle+++GO:0098835///presynaptic endocytic zone membrane+++GO:0032991///protein-containing complex+++GO:0030672///synaptic vesicle membrane+++GO:0005874///microtubule+++GO:0031966///mitochondrial membrane+++GO:0030054///cell junction+++GO:0005777///peroxisome+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005905///clathrin-coated pit+++GO:0012505///endomembrane system+++GO:0031410///cytoplasmic vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0099503///secretory vesicle+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005903///brush border+++GO:0098794///postsynapse","GO:0003924///GTPase activity+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0008289///lipid binding+++GO:0005525///GTP binding+++GO:0042803///protein homodimerization activity+++GO:0051433///BH2 domain binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0030276///clathrin binding+++GO:0008017///microtubule binding+++GO:0030742///GTP-dependent protein binding","GO:0012501///programmed cell death+++GO:0090141///positive regulation of mitochondrial fission+++GO:0043547///positive regulation of GTPase activity+++GO:0048488///synaptic vesicle endocytosis+++GO:0032459///regulation of protein oligomerization+++GO:0097194///execution phase of apoptosis+++GO:0043653///mitochondrial fragmentation involved in apoptotic process+++GO:1904579///cellular response to thapsigargin+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0090200///positive regulation of release of cytochrome c from mitochondria+++GO:0007005///mitochondrion organization+++GO:0090149///mitochondrial membrane fission+++GO:0070584///mitochondrion morphogenesis+++GO:0070585///protein localization to mitochondrion+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0036466///synaptic vesicle recycling via endosome+++GO:1990910///response to hypobaric hypoxia+++GO:0008637///apoptotic mitochondrial changes+++GO:1900063///regulation of peroxisome organization+++GO:0000266///mitochondrial fission+++GO:0048312///intracellular distribution of mitochondria+++GO:0061025///membrane fusion+++GO:0010821///regulation of mitochondrion organization+++GO:0050714///positive regulation of protein secretion+++GO:0010637///negative regulation of mitochondrial fusion+++GO:0016559///peroxisome fission+++GO:0060047///heart contraction+++GO:2000302///positive regulation of synaptic vesicle exocytosis+++GO:0007029///endoplasmic reticulum organization+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:0071396///cellular response to lipid+++GO:1905395///response to flavonoid+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0006897///endocytosis+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0051260///protein homooligomerization+++GO:0001836///release of cytochrome c from mitochondria+++GO:1903578///regulation of ATP metabolic process+++GO:0051259///protein complex oligomerization+++GO:0051289///protein homotetramerization+++GO:0070266///necroptotic process+++GO:0043065///positive regulation of apoptotic process","IPR019762///Dynamin, GTPase region, conserved site+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR030381///Dynamin-type guanine nucleotide-binding (G) domain+++IPR003130///Dynamin GTPase effector+++IPR000375///Dynamin central domain+++IPR030556///Dynamin-1-like protein+++IPR011993///PH-like domain superfamily+++IPR001401///Dynamin, GTPase domain+++IPR020850///GTPase effector domain+++IPR022812///Dynamin superfamily","[DNM1L_HUMAN|Reviewed]RecName: Full=Dynamin-1-like protein; EC=3.6.5.5; AltName: Full=Dnm1p/Vps1p-like protein; Short=DVLP; AltName: Full=Dynamin family member proline-rich carboxyl-terminal domain less; Short=Dymple; AltName: Full=Dynamin-like protein; AltName: Full=Dynamin-like protein 4; AltName: Full=Dynamin-like protein IV; Short=HdynIV; AltName: Full=Dynamin-related protein 1;+++[B4DDQ3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000396030}; SubName: Full=cDNA FLJ59840, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG56814.1};+++[B4DPZ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000390090}; SubName: Full=cDNA FLJ59948, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG60761.1};+++[B4DYR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56381, highly similar to Dynamin-1-like protein {ECO:0000313|EMBL:BAG63828.1};+++[D3DUW5_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_c {ECO:0000313|EMBL:EAW88523.1};+++[D3DUW6_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_f {ECO:0000313|EMBL:EAW88527.1};+++[D3DUW7_HUMAN|Unreviewed]SubName: Full=Dynamin 1-like, isoform CRA_a {ECO:0000313|EMBL:EAW88525.1};+++[F8VR28_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000450401};+++[F8VUJ9_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447845}; Flags: Fragment;+++[F8VYL3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448936};+++[F8VZ52_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447788}; Flags: Fragment;+++[F8W1W3_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000447013}; Flags: Fragment;+++[G8JLD5_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000350948};+++[H0YHY4_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448105}; Flags: Fragment;+++[H0YI79_HUMAN|Unreviewed]SubName: Full=Dynamin-1-like protein {ECO:0000313|Ensembl:ENSP00000448802}; Flags: Fragment;+++[Q32Q67_HUMAN|Unreviewed]SubName: Full=DNM1L protein {ECO:0000313|EMBL:AAI07764.1}; Flags: Fragment;"]
[1006,"'CDH8'",176,175,175.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0043083///synaptic cleft+++GO:0097060///synaptic membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043679///axon terminus+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0016342///catenin complex","GO:0042802///identical protein binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding","GO:0007268///chemical synaptic transmission+++GO:0007043///cell-cell junction assembly+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0009409///response to cold+++GO:0050807///regulation of synapse organization+++GO:0035249///synaptic transmission, glutamatergic+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","IPR039808///Cadherin+++IPR020894///Cadherin conserved site+++IPR002126///Cadherin-like+++IPR027397///Catenin binding domain superfamily+++IPR000233///Cadherin, cytoplasmic domain+++IPR015919///Cadherin-like superfamily","[CADH8_HUMAN|Reviewed]RecName: Full=Cadherin-8; Flags: Precursor;+++[J3KRI5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462018};+++[J3KT81_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462847}; Flags: Fragment;+++[J3KTG8_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000462976}; Flags: Fragment;+++[J3QKW5_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463266};+++[J3QLE6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000463511};+++[L8E7B0_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43150.1};+++[L8E8U5_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH8 {ECO:0000313|EMBL:CCQ43151.1};+++[Q3LID3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein Nbla04261 {ECO:0000313|EMBL:BAE45735.1}; Flags: Fragment;+++[X6R3Y6_HUMAN|Unreviewed]SubName: Full=Cadherin-8 {ECO:0000313|Ensembl:ENSP00000299345};"]
[10060,"'ABCC9'",375.8,397.12,386.46,"02010///ABC transporters","H00294///Dilated cardiomyopathy (DCM)+++H00731///Atrial fibrillation",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0042383///sarcolemma+++GO:0016020///membrane+++GO:0030017///sarcomere+++GO:0008282///inward rectifying potassium channel","GO:0044325///ion channel binding+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0015459///potassium channel regulator activity+++GO:0008281///sulfonylurea receptor activity+++GO:0005524///ATP binding+++GO:0005267///potassium channel activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005215///transporter activity","GO:1990573///potassium ion import across plasma membrane+++GO:0055085///transmembrane transport+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0006813///potassium ion transport+++GO:0051607///defense response to virus+++GO:0042493///response to drug","IPR000388///Sulphonylurea receptor+++IPR003439///ABC transporter-like+++IPR001475///ATP-binding cassette subfamily C member 9+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR017871///ABC transporter, conserved site+++IPR011527///ABC transporter type 1, transmembrane domain+++IPR003593///AAA+ ATPase domain+++IPR036640///ABC transporter type 1, transmembrane domain superfamily","[ABCC9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family C member 9; AltName: Full=Sulfonylurea receptor 2;+++[A0A024RAV7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW96456.1};+++[G3V1N6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000442604}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_a {ECO:0000313|EMBL:EAW96452.1};+++[H0YFV4_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000440521}; Flags: Fragment;+++[K4DI86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 9, isoform CRA_e {ECO:0000313|EMBL:EAW96458.1};+++[Q8N4N7_HUMAN|Unreviewed]SubName: Full=ABCC9 protein {ECO:0000313|EMBL:AAH33804.1}; SubName: Full=ATP-binding cassette sub-family C member 9 {ECO:0000313|Ensembl:ENSP00000317518};"]
[10061,"'ABCF2'",1516,1204,1360,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005740///mitochondrial envelope+++GO:0000786///nucleosome+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0005215///transporter activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity",null,"IPR003439///ABC transporter-like+++IPR007125///Histone H2A/H2B/H3+++IPR000558///Histone H2B+++IPR009072///Histone-fold+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR032781///ABC-transporter extension domain+++IPR017871///ABC transporter, conserved site+++IPR003593///AAA+ ATPase domain","[ABCF2_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family F member 2; AltName: Full=Iron-inhibited ABC transporter 2;+++[A0A090N7X1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24508.1};+++[A0A090N7Y2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 2 {ECO:0000313|EMBL:EAL24507.1};+++[C9JHK9_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000395785}; Flags: Fragment;+++[C9JZV3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 2 {ECO:0000313|Ensembl:ENSP00000419720}; Flags: Fragment;+++[L0R4T3_HUMAN|Unreviewed]RecName: Full=Histone H2B {ECO:0000256|RuleBase:RU000451};"]
[10062,"'NR1H3'",30,24,27,"03320///PPAR signaling pathway+++05160///Hepatitis C+++04931///Insulin resistance+++04932///Non-alcoholic fatty liver disease (NAFLD)",{"$nulls":3},"GO:0005634///nucleus+++GO:0043235///receptor complex+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0004879///nuclear receptor activity+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0038023///signaling receptor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003713///transcription coactivator activity+++GO:0015485///cholesterol binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0032810///sterol response element binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003707///steroid hormone receptor activity","GO:0051006///positive regulation of lipoprotein lipase activity+++GO:0090188///negative regulation of pancreatic juice secretion+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010887///negative regulation of cholesterol storage+++GO:0010745///negative regulation of macrophage derived foam cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0030522///intracellular receptor signaling pathway+++GO:0090341///negative regulation of secretion of lysosomal enzymes+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0060336///negative regulation of interferon-gamma-mediated signaling pathway+++GO:0007275///multicellular organism development+++GO:0050728///negative regulation of inflammatory response+++GO:0042632///cholesterol homeostasis+++GO:2000325///regulation of nuclear receptor transcription coactivator activity+++GO:0055092///sterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0055088///lipid homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0048550///negative regulation of pinocytosis+++GO:0043031///negative regulation of macrophage activation+++GO:0045861///negative regulation of proteolysis+++GO:0010875///positive regulation of cholesterol efflux+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0010870///positive regulation of receptor biosynthetic process+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0032570///response to progesterone+++GO:0043277///apoptotic cell clearance+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010867///positive regulation of triglyceride biosynthetic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032369///negative regulation of lipid transport+++GO:0032376///positive regulation of cholesterol transport+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0070328///triglyceride homeostasis+++GO:0044255///cellular lipid metabolic process","IPR035500///Nuclear hormone receptor-like domain superfamily+++IPR001628///Zinc finger, nuclear hormone receptor-type+++IPR001723///Nuclear hormone receptor+++IPR000536///Nuclear hormone receptor, ligand-binding domain+++IPR023257///Liver X receptor+++IPR013088///Zinc finger, NHR/GATA-type","[NR1H3_HUMAN|Reviewed]RecName: Full=Oxysterols receptor LXR-alpha; AltName: Full=Liver X receptor alpha; AltName: Full=Nuclear receptor subfamily 1 group H member 3;+++[B4DXU5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56172, highly similar to Oxysterols receptor LXR-alpha {ECO:0000313|EMBL:BAG63507.1};+++[B5MBY7_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000385073};+++[B6ZGS8_HUMAN|Unreviewed]SubName: Full=Liver X receptor alpha {ECO:0000313|EMBL:BAH02289.1};+++[C9J2C8_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000412636}; Flags: Fragment;+++[C9J4R0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000391005}; Flags: Fragment;+++[C9JBS2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403696}; Flags: Fragment;+++[C9JCS0_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000415591}; Flags: Fragment;+++[C9JEC2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000396132}; Flags: Fragment;+++[C9JJ16_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000403798}; Flags: Fragment;+++[C9JTS4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000413095}; Flags: Fragment;+++[E9PID2_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000432073};+++[E9PLL4_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000433271};+++[E9PPA1_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000434650}; Flags: Fragment;+++[F1D8N1_HUMAN|Unreviewed]SubName: Full=Liver X nuclear receptor alpha variant 1 {ECO:0000313|EMBL:ADZ17330.1};+++[F8WC63_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000406692};+++[F8WEY6_HUMAN|Unreviewed]SubName: Full=Oxysterols receptor LXR-alpha {ECO:0000313|Ensembl:ENSP00000407716};"]
[10063,"'COX17'",146,104,125,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00154///Cytochrome c oxidase",null,"GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0016531///copper chaperone activity+++GO:0046872///metal ion binding+++GO:0005507///copper ion binding+++GO:1903136///cuprous ion binding+++GO:0005515///protein binding","GO:1904960///positive regulation of cytochrome-c oxidase activity+++GO:0006825///copper ion transport+++GO:0006091///generation of precursor metabolites and energy+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0007420///brain development+++GO:0007507///heart development+++GO:0008284///positive regulation of cell proliferation","IPR007745///Cytochrome c oxidase copper chaperone+++IPR009069///Cysteine alpha-hairpin motif superfamily","[COX17_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase copper chaperone;+++[C9J8T6_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417651}; SubName: Full=HCG2022684, isoform CRA_b {ECO:0000313|EMBL:EAW79546.1};+++[H7C4E5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000417120}; Flags: Fragment;+++[H7C5P5_HUMAN|Unreviewed]SubName: Full=Cytochrome c oxidase copper chaperone {ECO:0000313|Ensembl:ENSP00000420406}; Flags: Fragment;"]
[100631383,"'FAM47E-STBD1'",15.92,31.99,23.955,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"IPR032743///FAM47 family+++IPR013783///Immunoglobulin-like fold+++IPR034838///Starch-binding domain-containing protein 1, CBM20 domain+++IPR013784///Carbohydrate-binding-like fold+++IPR002044///Carbohydrate binding module family 20","[FA47E_HUMAN|Reviewed]RecName: Full=Protein FAM47E;+++[D6RA91_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000423044}; Flags: Fragment;+++[F6W5V1_HUMAN|Unreviewed]SubName: Full=FAM47E-STBD1 readthrough {ECO:0000313|Ensembl:ENSP00000425528};"]
[100652748,"'TIMM23B'",135.84,177.24,156.54,"04212///Longevity regulating pathway - worm",{"$nulls":3},"GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005575///cellular_component+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0008320///protein transmembrane transporter activity","GO:0006886///intracellular protein transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0008150///biological_process+++GO:0015031///protein transport","IPR005681///Mitochondrial inner membrane translocase complex, subunit Tim23","[TI23B_HUMAN|Reviewed]RecName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B;+++[B4DDK6_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000389331}; SubName: Full=cDNA FLJ60010, moderately similar to Mitochondrial import inner membrane translocase subunit Tim23 {ECO:0000313|EMBL:BAG56767.1};+++[M0QZG8_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000470535};+++[S4R2X5_HUMAN|Unreviewed]SubName: Full=Putative mitochondrial import inner membrane translocase subunit Tim23B {ECO:0000313|Ensembl:ENSP00000473724};"]
[100652824,"'KIAA2012'",0,1,0.5,"05225///Hepatocellular carcinoma+++04390///Hippo signaling pathway+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04150///mTOR signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05166///HTLV-I infection+++05165///Human papillomavirus infection+++04916///Melanogenesis+++04310///Wnt signaling pathway+++05224///Breast cancer+++04550///Signaling pathways regulating pluripotency of stem cells+++05205///Proteoglycans in cancer","H00048///Hepatocellular carcinoma+++H00031///Breast cancer","M00677///Wnt signaling",null,"GO:0055038///recycling endosome membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0030165///PDZ domain binding+++GO:0042813///Wnt-activated receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017147///Wnt-protein binding+++GO:0005109///frizzled binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding","GO:0033077///T cell differentiation in thymus+++GO:0019827///stem cell population maintenance+++GO:0048103///somatic stem cell division+++GO:0030182///neuron differentiation+++GO:0014834///skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration+++GO:0038031///non-canonical Wnt signaling pathway via JNK cascade+++GO:0042327///positive regulation of phosphorylation+++GO:0060231///mesenchymal to epithelial transition+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0046330///positive regulation of JNK cascade+++GO:2000726///negative regulation of cardiac muscle cell differentiation+++GO:0060054///positive regulation of epithelial cell proliferation involved in wound healing+++GO:0071300///cellular response to retinoic acid+++GO:0060070///canonical Wnt signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0042666///negative regulation of ectodermal cell fate specification","IPR031440///Protein of unknown function DUF4670","[K2012_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA2012 {ECO:0000305};+++[A0A1B0GV91_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000490419}; Flags: Fragment;+++[H7C5G6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA2012 {ECO:0000313|Ensembl:ENSP00000419834};"]
[100652833,"'LOC100652833'",4,1,2.5,{"$nulls":4},"GO:0016021///integral component of membrane",{"$nulls":3},"[P121A_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;+++[P121C_HUMAN|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121C; AltName: Full=Nuclear pore membrane protein 121-2; Short=POM121-2; AltName: Full=Pore membrane protein of 121 kDa C;+++[P12L1_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1;+++[P12LL_HUMAN|diamond]RecName: Full=Putative POM121-like protein 1-like;+++[PO121_RAT|diamond]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa; AltName: Full=p145;"]
[100652901,"'LOC100652901'",7.94,16.04,11.99,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0010494///cytoplasmic stress granule","GO:0003727///single-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding","GO:0032197///transposition, RNA-mediated","IPR004244///Transposase, L1+++IPR035300///L1 transposable element, dsRBD-like domain+++IPR035301///L1 transposable element, trimerization domain","[Q6ZNX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26942 fis, clone RCT07464 {ECO:0000313|EMBL:BAC85354.1};"]
[100653049,"'LOC100653049'",3.83,0,1.915,"04915///Estrogen signaling pathway","H00708///Naegeli-Franceschetti-Jadassohn syndrome+++H00738///Ichthyosis with confetti+++H00796///Dermatopathia pigmentosa reticularis+++H00667///Woolly hair+++H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00726///Meesmann corneal dystrophy+++H00584///Epidermolysis bullosa simplex+++H00684///Pachyonychia congenita+++H00723///Non-epidermolytic palmoplantar keratoderma (NEPPK)+++H01673///Palmoplantar keratoderma+++H00724///White sponge nevus",null,null,"GO:0005882///intermediate filament","GO:0005198///structural molecule activity","GO:0008544///epidermis development+++GO:0031424///keratinization+++GO:0070268///cornification","IPR001664///Intermediate filament protein+++IPR039008///Intermediate filament, rod domain+++IPR018039///Intermediate filament protein, conserved site+++IPR002957///Keratin, type I","[KRT34_HUMAN|Reviewed]RecName: Full=Keratin, type I cuticular Ha4; AltName: Full=Hair keratin, type I Ha4; AltName: Full=Keratin-34; Short=K34;+++[A0A140TA62_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000459812};"]
[100653133,"'LOC100653133'",0,1,0.5,{"$nulls":7},"IPR026737///Golgin subfamily A member 6-like","[GG6L1_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 1;+++[GG6L2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 2;+++[GG6L6_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 6;+++[GG6L7_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 7 {ECO:0000305};+++[GG6LV_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};"]
[100653515,"'CEP295NL'",1,0,0.5,{"$nulls":4},"GO:0005929///cilium+++GO:0042995///cell projection","GO:0008191///metalloendopeptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity",null,"[C295L_HUMAN|Reviewed]RecName: Full=CEP295 N-terminal-like protein {ECO:0000305}; AltName: Full=KIAA1731 N-terminal like protein {ECO:0000312|HGNC:HGNC:44659};+++[K7EL90_HUMAN|Unreviewed]SubName: Full=CEP295 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000465968}; Flags: Fragment;"]
[10066,"'SCAMP2'",3253,3163,3208,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0055038///recycling endosome membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0032588///trans-Golgi network membrane+++GO:0030133///transport vesicle","GO:0005515///protein binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","IPR007273///SCAMP","[SCAM2_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 2; Short=Secretory carrier membrane protein 2;+++[A0A140VK92_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[A8K769_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BMN2_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BN93_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};+++[H3BPL9_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BQW2_HUMAN|Unreviewed]SubName: Full=Secretory carrier-associated membrane protein 2 {ECO:0000313|Ensembl:ENSP00000455963};+++[H3BUB6_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[H3BV04_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;+++[Q6IBK3_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122};"]
[10067,"'SCAMP3'",2588,2196,2392,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0055038///recycling endosome membrane+++GO:0070062///extracellular exosome+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032588///trans-Golgi network membrane","GO:0031625///ubiquitin protein ligase binding","GO:0006892///post-Golgi vesicle-mediated transport+++GO:0015031///protein transport","IPR007273///SCAMP","[SCAM3_HUMAN|Reviewed]RecName: Full=Secretory carrier-associated membrane protein 3; Short=Secretory carrier membrane protein 3;+++[Q6FHJ5_HUMAN|Unreviewed]RecName: Full=Secretory carrier-associated membrane protein {ECO:0000256|RuleBase:RU363122}; Short=Secretory carrier membrane protein {ECO:0000256|RuleBase:RU363122}; Flags: Fragment;"]
[10068,"'IL18BP'",119,171,145,{"$nulls":4},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0042007///interleukin-18 binding+++GO:0048019///receptor antagonist activity","GO:0070301///cellular response to hydrogen peroxide+++GO:0032496///response to lipopolysaccharide+++GO:0071356///cellular response to tumor necrosis factor+++GO:0042088///T-helper 1 type immune response+++GO:0071345///cellular response to cytokine stimulus+++GO:1900116///extracellular negative regulation of signal transduction+++GO:0035655///interleukin-18-mediated signaling pathway","IPR039681///Interleukin-18-binding protein+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain","[I18BP_HUMAN|Reviewed]RecName: Full=Interleukin-18-binding protein; Short=IL-18BP; AltName: Full=Tadekinig-alfa; Flags: Precursor;+++[A0A024R5G2_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_d {ECO:0000313|EMBL:EAW74817.1};+++[A0A024R5I1_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_c {ECO:0000313|EMBL:EAW74820.1};+++[A0A024R5M7_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_b {ECO:0000313|EMBL:EAW74819.1};+++[G3V1C5_HUMAN|Unreviewed]SubName: Full=Interleukin 18 binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW74812.1}; SubName: Full=Interleukin-18-binding protein {ECO:0000313|Ensembl:ENSP00000434717};"]
[10069,"'RWDD2B'",191,222,206.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","IPR017359///Uncharacterised conserved protein UCP038021, RWD+++IPR016135///Ubiquitin-conjugating enzyme/RWD-like+++IPR006575///RWD domain+++IPR010541///Domain of unknown function DUF1115","[RWD2B_HUMAN|Reviewed]RecName: Full=RWD domain-containing protein 2B;"]
[10071,"'MUC12'",2,5,3.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0001558///regulation of cell growth+++GO:0016266///O-glycan processing+++GO:0002223///stimulatory C-type lectin receptor signaling pathway","IPR013032///EGF-like, conserved site+++IPR000082///SEA domain+++IPR036364///SEA domain superfamily","[MUC12_HUMAN|Reviewed]RecName: Full=Mucin-12; Short=MUC-12; AltName: Full=Mucin-11; Short=MUC-11; Flags: Precursor;+++[A1L198_HUMAN|Unreviewed]SubName: Full=MUC12 protein {ECO:0000313|EMBL:AAI27878.1}; Flags: Fragment;+++[H7BXN1_HUMAN|Unreviewed]SubName: Full=Mucin-12 {ECO:0000313|Ensembl:ENSP00000306919}; Flags: Fragment;+++[L8E898_HUMAN|Unreviewed]SubName: Full=Alternative protein MUC12 {ECO:0000313|EMBL:CCQ42956.1};"]
[10072,"'DPP3'",1143,922,1032.5,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016607///nuclear speck","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004177///aminopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008237///metallopeptidase activity+++GO:0008239///dipeptidyl-peptidase activity","GO:0006508///proteolysis","IPR039461///Peptidase family M49+++IPR005317///Dipeptidyl-peptidase 3","[DPP3_HUMAN|Reviewed]RecName: Full=Dipeptidyl peptidase 3; EC=3.4.14.4 {ECO:0000269|PubMed:11209758, ECO:0000269|PubMed:1515063, ECO:0000269|PubMed:3233187, ECO:0000269|PubMed:9425109}; AltName: Full=Dipeptidyl aminopeptidase III; AltName: Full=Dipeptidyl arylamidase III; AltName: Full=Dipeptidyl peptidase III; Short=DPP III; AltName: Full=Enkephalinase B;+++[E9PKK8_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000431606}; Flags: Fragment;+++[E9PNX5_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000437101}; Flags: Fragment;+++[E9PPK9_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000432618}; Flags: Fragment;+++[E9PQ14_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000434518}; Flags: Fragment;+++[E9PQF2_HUMAN|Unreviewed]SubName: Full=Dipeptidyl peptidase 3 {ECO:0000313|Ensembl:ENSP00000436820}; Flags: Fragment;+++[G3V180_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[G3V1D3_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};+++[Q5JPB8_HUMAN|Unreviewed]RecName: Full=Dipeptidyl peptidase 3 {ECO:0000256|PIRNR:PIRNR007828}; EC=3.4.14.4 {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl aminopeptidase III {ECO:0000256|PIRNR:PIRNR007828}; AltName: Full=Dipeptidyl peptidase III {ECO:0000256|PIRNR:PIRNR007828};"]
[10073,"'SNUPN'",117,102,109.5,"03013///RNA transport",{"$nulls":3},"GO:0005829///cytosol+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000339///RNA cap binding+++GO:0003723///RNA binding+++GO:0061608///nuclear import signal receptor activity+++GO:0005515///protein binding","GO:0006606///protein import into nucleus+++GO:0061015///snRNA import into nucleus+++GO:0000387///spliceosomal snRNP assembly+++GO:0051170///import into nucleus","IPR017336///Snurportin-1+++IPR024721///Snurportin-1, N-terminal+++IPR002652///Importin-alpha, importin-beta-binding domain","[SPN1_HUMAN|Reviewed]RecName: Full=Snurportin-1; AltName: Full=RNA U transporter 1;+++[H3BQR0_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000455894}; Flags: Fragment;+++[H3BRI5_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456260}; Flags: Fragment;+++[H3BSK1_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000456742}; Flags: Fragment;+++[H3BTA6_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457093}; Flags: Fragment;+++[H3BUB4_HUMAN|Unreviewed]SubName: Full=Snurportin-1 {ECO:0000313|Ensembl:ENSP00000457562}; Flags: Fragment;"]
[10075,"'HUWE1'",4630,5977,5303.5,"04120///Ubiquitin mediated proteolysis","H00658///Syndromic X-linked mental retardation",null,null,"GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0003723///RNA binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006281///DNA repair+++GO:0016567///protein ubiquitination+++GO:0030154///cell differentiation+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0043312///neutrophil degranulation+++GO:0006284///base-excision repair+++GO:0000209///protein polyubiquitination+++GO:0006513///protein monoubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016574///histone ubiquitination","IPR010314///E3 ubiquitin ligase, domain of unknown function DUF913+++IPR035983///HECT, E3 ligase catalytic domain+++IPR009060///UBA-like superfamily+++IPR025527///Domain of unknown function DUF4414+++IPR037197///WWE domain superfamily+++IPR016024///Armadillo-type fold+++IPR004170///WWE domain+++IPR015940///Ubiquitin-associated domain+++IPR010309///E3 ubiquitin ligase, domain of unknown function DUF908+++IPR000569///HECT domain","[HUWE1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase HUWE1; EC=2.3.2.26; AltName: Full=ARF-binding protein 1; Short=ARF-BP1; AltName: Full=HECT, UBA and WWE domain-containing protein 1; AltName: Full=HECT-type E3 ubiquitin transferase HUWE1; AltName: Full=Homologous to E6AP carboxyl terminus homologous protein 9; Short=HectH9; AltName: Full=Large structure of UREB1; Short=LASU1; AltName: Full=Mcl-1 ubiquitin ligase E3; Short=Mule; AltName: Full=Upstream regulatory element-binding protein 1; Short=URE-B1; Short=URE-binding protein 1;+++[A0A024R9U8_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW93163.1};+++[A0A024R9W5_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW93166.1};+++[A0A024R9Y3_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW93165.1};+++[A0A087X146_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000483891}; Flags: Fragment;+++[A0A087X1S3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000484417}; Flags: Fragment;+++[A0A1B0GXC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000413651}; Flags: Fragment;+++[H0Y659_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase HUWE1 {ECO:0000313|Ensembl:ENSP00000403236}; Flags: Fragment;+++[L8E996_HUMAN|Unreviewed]SubName: Full=Alternative protein HUWE1 {ECO:0000313|EMBL:CCQ43744.1};+++[Q3B7K0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAI07577.1}; Flags: Fragment;+++[Q5H924_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42656.1}; Flags: Fragment;+++[Q5H935_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42644.1}; Flags: Fragment;+++[Q5H962_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42353.1};+++[Q5H963_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42352.1}; Flags: Fragment;+++[Q5H964_HUMAN|Unreviewed]SubName: Full=HECT, UBA and WWE domain containing 1 {ECO:0000313|EMBL:CAI42351.1}; Flags: Fragment;+++[Q8IWJ0_HUMAN|Unreviewed]SubName: Full=HUWE1 protein {ECO:0000313|EMBL:AAH38184.1}; Flags: Fragment;"]
[10076,"'PTPRU'",2032,2652,2342,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:0030027///lamellipodium+++GO:0098978///glutamatergic synapse+++GO:0005911///cell-cell junction+++GO:0099061///integral component of postsynaptic density membrane+++GO:0016324///apical plasma membrane+++GO:0043005///neuron projection+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0098982///GABA-ergic synapse+++GO:0030426///growth cone+++GO:0005887///integral component of plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0008013///beta-catenin binding+++GO:0017147///Wnt-protein binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0016787///hydrolase activity","GO:0034109///homotypic cell-cell adhesion+++GO:0016311///dephosphorylation+++GO:0031100///animal organ regeneration+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0007185///transmembrane receptor protein tyrosine phosphatase signaling pathway+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0032835///glomerulus development+++GO:0002548///monocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0034394///protein localization to cell surface+++GO:0007155///cell adhesion+++GO:0050807///regulation of synapse organization+++GO:0006470///protein dephosphorylation+++GO:0030154///cell differentiation+++GO:0010977///negative regulation of neuron projection development+++GO:0030032///lamellipodium assembly+++GO:0007411///axon guidance+++GO:0030336///negative regulation of cell migration+++GO:0090260///negative regulation of retinal ganglion cell axon guidance+++GO:0003105///negative regulation of glomerular filtration+++GO:0003093///regulation of glomerular filtration+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0051384///response to glucocorticoid+++GO:0008285///negative regulation of cell proliferation+++GO:0036060///slit diaphragm assembly","IPR000998///MAM domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR000387///Tyrosine specific protein phosphatases domain+++IPR003595///Protein-tyrosine phosphatase, catalytic+++IPR013783///Immunoglobulin-like fold+++IPR016130///Protein-tyrosine phosphatase, active site+++IPR003961///Fibronectin type III+++IPR000242///PTP type protein phosphatase+++IPR036179///Immunoglobulin-like domain superfamily+++IPR036116///Fibronectin type III superfamily+++IPR029021///Protein-tyrosine phosphatase-like","[PTPRU_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase U; Short=R-PTP-U; EC=3.1.3.48; AltName: Full=Pancreatic carcinoma phosphatase 2; Short=PCP-2; AltName: Full=Protein-tyrosine phosphatase J; Short=PTP-J; Short=hPTP-J; AltName: Full=Protein-tyrosine phosphatase pi; Short=PTP pi; AltName: Full=Protein-tyrosine phosphatase receptor omicron; Short=PTP-RO; AltName: Full=Receptor-type protein-tyrosine phosphatase psi; Short=R-PTP-psi; Flags: Precursor;+++[H0YH11_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[H0YH60_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[L8ECC6_HUMAN|Unreviewed]SubName: Full=Alternative protein PTPRU {ECO:0000313|EMBL:CCQ43332.1};+++[Q9P0U2_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase {ECO:0000313|EMBL:AAF67472.1};"]
[10078,"'TSSC4'",540,452,496,{"$nulls":5},"GO:0005515///protein binding",null,"IPR029338///Tumour suppressing sub-chromosomal transferable candidate 4","[TSSC4_HUMAN|Reviewed]RecName: Full=Protein TSSC4; AltName: Full=Tumor-suppressing STF cDNA 4 protein; AltName: Full=Tumor-suppressing subchromosomal transferable fragment candidate gene 4 protein;+++[A0A024RCB9_HUMAN|Unreviewed]SubName: Full=Tumor suppressing subtransferable candidate 4, isoform CRA_a {ECO:0000313|EMBL:EAX02513.1};+++[A6NCC9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000370380};+++[C9JDU0_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000403475}; Flags: Fragment;+++[C9JHT9_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000396925}; Flags: Fragment;+++[C9JJV1_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000416937}; Flags: Fragment;+++[E9PL88_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000431430}; Flags: Fragment;+++[E9PME3_HUMAN|Unreviewed]SubName: Full=Protein TSSC4 {ECO:0000313|Ensembl:ENSP00000435013}; Flags: Fragment;"]
[10079,"'ATP9A'",635,853,744,null,"H00624///Familial cholestasis",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0005769///early endosome+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding","GO:0006897///endocytosis+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport","IPR001757///P-type ATPase+++IPR036412///HAD-like superfamily+++IPR008250///P-type ATPase, A domain superfamily+++IPR023214///HAD superfamily+++IPR032631///P-type ATPase, N-terminal+++IPR023298///P-type ATPase, transmembrane domain superfamily+++IPR023299///P-type ATPase, cytoplasmic domain N+++IPR032630///P-type ATPase, C-terminal+++IPR006539///P-type ATPase, subfamily IV+++IPR030356///Probable phospholipid-transporting ATPase IIA+++IPR018303///P-type ATPase, phosphorylation site","[ATP9A_HUMAN|Reviewed]RecName: Full=Probable phospholipid-transporting ATPase IIA; EC=3.6.3.1; AltName: Full=ATPase class II type 9A;+++[A0A0A0MR22_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[B4DR18_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033};+++[Q2NLD0_HUMAN|Unreviewed]RecName: Full=Phospholipid-transporting ATPase {ECO:0000256|RuleBase:RU362033}; EC=3.6.3.1 {ECO:0000256|RuleBase:RU362033}; Flags: Fragment;+++[Q96B35_HUMAN|Unreviewed]SubName: Full=ATP9A protein {ECO:0000313|EMBL:AAH16044.1}; Flags: Fragment;"]
[1008,"'CDH10'",404,459,431.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099059///integral component of presynaptic active zone membrane+++GO:0016342///catenin complex+++GO:0098982///GABA-ergic synapse+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0099060///integral component of postsynaptic specialization membrane","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0008092///cytoskeletal protein binding+++GO:0042803///protein homodimerization activity","GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0007043///cell-cell junction assembly+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0098609///cell-cell adhesion","IPR020894///Cadherin conserved site+++IPR000233///Cadherin, cytoplasmic domain+++IPR027397///Catenin binding domain superfamily+++IPR002126///Cadherin-like+++IPR015919///Cadherin-like superfamily+++IPR039808///Cadherin","[CAD10_HUMAN|Reviewed]RecName: Full=Cadherin-10; AltName: Full=T2-cadherin; Flags: Precursor;+++[D6RJG0_HUMAN|Unreviewed]SubName: Full=Cadherin-10 {ECO:0000313|Ensembl:ENSP00000425653};+++[L8ECD4_HUMAN|Unreviewed]SubName: Full=Alternative protein CDH10 {ECO:0000313|EMBL:CCQ43372.1};+++[X5D8X5_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform A {ECO:0000313|EMBL:AHW56448.1}; SubName: Full=Cadherin 10, type 2 (T2-cadherin) {ECO:0000313|EMBL:EAX10742.1}; Flags: Fragment;+++[X5DNG6_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform B {ECO:0000313|EMBL:AHW56446.1}; Flags: Fragment;+++[X5DQT8_HUMAN|Unreviewed]SubName: Full=Cadherin 10 type 2 isoform C {ECO:0000313|EMBL:AHW56447.1}; Flags: Fragment;"]
[10081,"'PDCD7'",195,181,188,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005689///U12-type spliceosomal complex",null,"GO:0006915///apoptotic process+++GO:0008380///RNA splicing+++GO:0051384///response to glucocorticoid+++GO:0000398///mRNA splicing, via spliceosome","IPR031974///Programmed cell death protein 7","[PDCD7_HUMAN|Reviewed]RecName: Full=Programmed cell death protein 7; AltName: Full=ES18; Short=hES18;+++[A3KMF9_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAI31705.1}; Flags: Fragment;+++[H3BT73_HUMAN|Unreviewed]SubName: Full=Programmed cell death protein 7 {ECO:0000313|Ensembl:ENSP00000457053}; Flags: Fragment;+++[Q569I4_HUMAN|Unreviewed]SubName: Full=PDCD7 protein {ECO:0000313|EMBL:AAH92464.1}; Flags: Fragment;+++[Q6IEG3_HUMAN|Unreviewed]SubName: Full=Programmed cell death 7, isoform CRA_a {ECO:0000313|EMBL:EAW77713.1}; SubName: Full=U11/U12 snRNP 59K {ECO:0000313|EMBL:DAA05494.1};"]
[10082,"'GPC6'",785,1667,1226,null,"H02154///Omodysplasia+++H00493///Heparan sulfate proteoglycan gene defects",null,null,"GO:0016020///membrane+++GO:0031225///anchored component of membrane+++GO:0005634///nucleus+++GO:0062023///collagen-containing extracellular matrix+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0046658///anchored component of plasma membrane+++GO:0043202///lysosomal lumen+++GO:0005796///Golgi lumen+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding+++GO:1904929///coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway","GO:0006027///glycosaminoglycan catabolic process+++GO:0001523///retinoid metabolic process+++GO:0016477///cell migration+++GO:0009966///regulation of signal transduction+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane","IPR001863///Glypican+++IPR031183///Glypican-6+++IPR019803///Glypican, conserved site","[GPC6_HUMAN|Reviewed]RecName: Full=Glypican-6; Contains: RecName: Full=Secreted glypican-6; Flags: Precursor;+++[A0A087WT82_HUMAN|Unreviewed]SubName: Full=Glypican-6 {ECO:0000313|Ensembl:ENSP00000477667};"]
[100820829,"'MYZAP'",19,8,13.5,{"$nulls":4},"GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0030018///Z disc","GO:0005515///protein binding","GO:0035556///intracellular signal transduction","IPR028273///Myocardial zonula adherens protein","[MYZAP_HUMAN|Reviewed]RecName: Full=Myocardial zonula adherens protein; AltName: Full=GRINL1A upstream protein; Short=Gup; Flags: Precursor;+++[A0A024R5W4_HUMAN|Unreviewed]SubName: Full=HCG40688, isoform CRA_a {ECO:0000313|EMBL:EAW77523.1};+++[H0YCD3_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000431396}; Flags: Fragment;+++[H3BTD5_HUMAN|Unreviewed]SubName: Full=Myocardial zonula adherens protein {ECO:0000313|Ensembl:ENSP00000457126}; Flags: Fragment;"]
[10084,"'PQBP1'",527,337,432,"03040///Spliceosome","H01913///Renpenning syndrome+++H00480///Non-syndromic X-linked mental retardation","M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0010494///cytoplasmic stress granule+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0071598///neuronal ribonucleoprotein granule","GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043021///ribonucleoprotein complex binding","GO:0006355///regulation of transcription, DNA-templated+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0032481///positive regulation of type I interferon production+++GO:0031175///neuron projection development+++GO:0002218///activation of innate immune response+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071360///cellular response to exogenous dsRNA+++GO:0002230///positive regulation of defense response to virus by host+++GO:0008380///RNA splicing+++GO:0051607///defense response to virus+++GO:0043484///regulation of RNA splicing+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0048814///regulation of dendrite morphogenesis","IPR036020///WW domain superfamily+++IPR001202///WW domain","[PQBP1_HUMAN|Reviewed]RecName: Full=Polyglutamine-binding protein 1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; Short=PQBP-1 {ECO:0000303|PubMed:10332029, ECO:0000303|PubMed:11163963}; AltName: Full=38 kDa nuclear protein containing a WW domain {ECO:0000303|PubMed:10198427}; Short=Npw38 {ECO:0000303|PubMed:10198427}; AltName: Full=Polyglutamine tract-binding protein 1 {ECO:0000303|PubMed:10332029};+++[A0A0S2Z4V5_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33958.1}; SubName: Full=Polyglutamine binding protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW50737.1}; Flags: Fragment;+++[A0A0S2Z556_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33959.1}; Flags: Fragment;+++[H7C053_HUMAN|Unreviewed]SubName: Full=Polyglutamine-binding protein 1 {ECO:0000313|Ensembl:ENSP00000393013}; Flags: Fragment;+++[Q4VY28_HUMAN|Unreviewed]SubName: Full=Polyglutamine binding protein variant 12 {ECO:0000313|EMBL:CAJ00551.1}; Flags: Fragment;"]
[10085,"'EDIL3'",4958,8204,6581,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:1903561///extracellular vesicle","GO:0005201///extracellular matrix structural constituent+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0010811///positive regulation of cell-substrate adhesion","IPR029828///EGF-like repeat and discoidin I-like domain-containing protein 3+++IPR001881///EGF-like calcium-binding domain+++IPR000742///EGF-like domain+++IPR018097///EGF-like calcium-binding, conserved site+++IPR013032///EGF-like, conserved site+++IPR000421///Coagulation factor 5/8 C-terminal domain+++IPR008979///Galactose-binding-like domain superfamily+++IPR000152///EGF-type aspartate/asparagine hydroxylation site","[EDIL3_HUMAN|Reviewed]RecName: Full=EGF-like repeat and discoidin I-like domain-containing protein 3; AltName: Full=Developmentally-regulated endothelial cell locus 1 protein; AltName: Full=Integrin-binding protein DEL1; Flags: Precursor;"]
[100861412,"'FSBP'",16.21,28.91,22.56,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","IPR028002///Myb/SANT-like DNA-binding domain","[FSBP_HUMAN|Reviewed]RecName: Full=Fibrinogen silencer-binding protein;+++[J3KSW4_HUMAN|Unreviewed]SubName: Full=Fibrinogen silencer-binding protein {ECO:0000313|Ensembl:ENSP00000462684};"]
[100862671,"'TMEM265'",138,149,143.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,"GO:0009607///response to biotic stimulus","IPR007593///CD225/Dispanin family","[TM265_HUMAN|Reviewed]RecName: Full=Transmembrane protein 265 {ECO:0000312|HGNC:HGNC:51241};"]
[10087,"'COL4A3BP'",339,446.88,392.94,"05202///Transcriptional misregulation in cancer+++05213///Endometrial cancer+++05224///Breast cancer+++04140///Autophagy - animal+++05210///Colorectal cancer+++05220///Chronic myeloid leukemia+++05212///Pancreatic cancer+++05214///Glioma+++05216///Thyroid cancer+++04137///Mitophagy - animal+++05218///Melanoma+++05217///Basal cell carcinoma+++03460///Fanconi anemia pathway+++05226///Gastric cancer+++05225///Hepatocellular carcinoma+++05222///Small cell lung cancer+++05200///Pathways in cancer+++05223///Non-small cell lung cancer","H00773///Autosomal dominant mental retardation",null,null,"GO:0005581///collagen trimer+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005623///cell+++GO:0048471///perinuclear region of cytoplasm","GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0120017///intermembrane ceramide transfer activity+++GO:0008289///lipid binding+++GO:1902388///ceramide 1-phosphate transporter activity+++GO:0016301///kinase activity+++GO:1902387///ceramide 1-phosphate binding+++GO:0097001///ceramide binding+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0006869///lipid transport+++GO:0034976///response to endoplasmic reticulum stress+++GO:0003007///heart morphogenesis+++GO:0055088///lipid homeostasis+++GO:0001701///in utero embryonic development+++GO:0008283///cell proliferation+++GO:0006672///ceramide metabolic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0120009///intermembrane lipid transfer+++GO:0007029///endoplasmic reticulum organization+++GO:0120012///intermembrane sphingolipid transfer+++GO:0035621///ER to Golgi ceramide transport+++GO:0035627///ceramide transport+++GO:0000902///cell morphogenesis+++GO:1902389///ceramide 1-phosphate transport+++GO:0070584///mitochondrion morphogenesis+++GO:0006936///muscle contraction+++GO:0007165///signal transduction+++GO:0006955///immune response","IPR011993///PH-like domain superfamily+++IPR002913///START domain+++IPR001849///Pleckstrin homology domain+++IPR023393///START-like domain superfamily","[C43BP_HUMAN|Reviewed]RecName: Full=Collagen type IV alpha-3-binding protein; AltName: Full=Ceramide transfer protein {ECO:0000303|PubMed:14685229}; Short=hCERT; AltName: Full=Goodpasture antigen-binding protein; Short=GPBP; AltName: Full=START domain-containing protein 11; Short=StARD11; AltName: Full=StAR-related lipid transfer protein 11;+++[A0A024RAJ5_HUMAN|Unreviewed]SubName: Full=Collagen, type IV, alpha 3 (Goodpasture antigen) binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW95758.1};+++[A0A0A0MRE4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000350046}; Flags: Fragment;+++[A0A2R8Y3S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493565}; Flags: Fragment;+++[A0A2R8Y5G0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494760}; Flags: Fragment;+++[A0A2R8Y5H3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494810}; Flags: Fragment;+++[A0A2R8Y5S9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494804};+++[A0A2R8Y773_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495798}; Flags: Fragment;+++[A0A2R8Y7C5_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496016};+++[A0A2R8Y7Q9_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496462};+++[A0A2R8YCI0_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000493604};+++[A0A2R8YDX6_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495038}; Flags: Fragment;+++[A0A2R8YE18_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495172};+++[A0A2R8YE59_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494073}; Flags: Fragment;+++[A0A2R8YEA4_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000495430};+++[A0A2R8YEK8_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494424};+++[A0A2R8YFA1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000494969}; Flags: Fragment;+++[A0A2R8YFI2_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000496472};+++[A0A2U3TZL3_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000369862}; Flags: Fragment;+++[H0Y9J1_HUMAN|Unreviewed]SubName: Full=Collagen type IV alpha-3-binding protein {ECO:0000313|Ensembl:ENSP00000424244}; Flags: Fragment;"]
[100873985,"'MED14OS'",3,1,2,{"$nulls":8},"[M14OS_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein MED14OS {ECO:0000305}; AltName: Full=MED14 antisense gene protein 1 {ECO:0000305}; AltName: Full=MED14 opposite strand protein {ECO:0000312|HGNC:HGNC:40162};"]
[100885848,"'PTGES3L'",6.7,13.52,10.11,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0051879///Hsp90 protein binding+++GO:0051087///chaperone binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","IPR007052///CS domain+++IPR008978///HSP20-like chaperone","[PTG3L_HUMAN|Reviewed]RecName: Full=Putative protein PTGES3L; AltName: Full=Prostaglandin E synthase 3-like;+++[B9A003_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000386902};+++[C9JG77_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000404440}; Flags: Fragment;+++[H7C1Q7_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000467778}; Flags: Fragment;+++[K7N7A2_HUMAN|Unreviewed]SubName: Full=Putative protein PTGES3L {ECO:0000313|Ensembl:ENSP00000401675}; Flags: Fragment;"]
[100885850,"'PTGES3L-AARSD1'",11.07,22.2,16.635,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0004813///alanine-tRNA ligase activity","GO:0006419///alanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation","IPR008978///HSP20-like chaperone+++IPR007052///CS domain+++IPR018165///Alanyl-tRNA synthetase, class IIc, core domain+++IPR018163///Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily+++IPR009000///Translation protein, beta-barrel domain superfamily+++IPR012947///Threonyl/alanyl tRNA synthetase, SAD+++IPR018164///Alanyl-tRNA synthetase, class IIc, N-terminal","[AASD1_HUMAN|Reviewed]RecName: Full=Alanyl-tRNA editing protein Aarsd1; AltName: Full=Alanyl-tRNA synthetase domain-containing protein 1;+++[C9J5N1_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000386254};+++[C9JUA3_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393780}; Flags: Fragment;+++[H7C054_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000393019}; Flags: Fragment;+++[L7N2F6_HUMAN|Unreviewed]SubName: Full=PTGES3L-AARSD1 readthrough {ECO:0000313|Ensembl:ENSP00000407951}; Flags: Fragment;"]
[10089,"'KCNK7'",0,1,0.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0022841///potassium ion leak channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005267///potassium channel activity","GO:0006813///potassium ion transport+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0034765///regulation of ion transmembrane transport","IPR005408///Two pore domain potassium channel, TWIK family+++IPR013099///Potassium channel domain+++IPR003280///Two pore domain potassium channel+++IPR003092///Two pore domain potassium channel, TASK family","[KCNK7_HUMAN|Reviewed]RecName: Full=Potassium channel subfamily K member 7;+++[A0A024R5B0_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_c {ECO:0000313|EMBL:EAW74415.1};+++[A0A024R5F5_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7, isoform CRA_b {ECO:0000313|EMBL:EAW74414.1};+++[H0YCM4_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000431950}; Flags: Fragment;+++[H0YEB9_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily K member 7 {ECO:0000313|Ensembl:ENSP00000435449}; Flags: Fragment;+++[Q3MI97_HUMAN|Unreviewed]SubName: Full=KCNK7 protein {ECO:0000313|EMBL:AAI03812.2}; Flags: Fragment;+++[Q3SYI1_HUMAN|Unreviewed]SubName: Full=Potassium channel, subfamily K, member 7 {ECO:0000313|EMBL:AAI03811.1};"]
[1009,"'CDH11'",1891,2147,2019,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01513///Retinoblastoma",null,null,"GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0070062///extracellular exosome+++GO:0016342///catenin complex+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse+++GO:0005737///cytoplasm","GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding","GO:0021957///corticospinal tract morphogenesis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0001503///ossification+++GO:0034332///adherens junction organization+++GO:0007155///cell adhesion+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007043///cell-cell junction assembly+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0050804///modulation of chemical synaptic transmission+++GO:0001501///skeletal system development","IPR002126///Cadherin-like+++IPR039808///Cadherin+++IPR027397///Catenin binding domain superfamily+++IPR015919///Cadherin-like superfamily+++IPR020894///Cadherin conserved site+++IPR000233///Cadherin, cytoplasmic domain","[CAD11_HUMAN|Reviewed]RecName: Full=Cadherin-11; AltName: Full=OSF-4; AltName: Full=Osteoblast cadherin; Short=OB-cadherin; Flags: Precursor;+++[A0A087X227_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000484650}; Flags: Fragment;+++[H3BP26_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455120}; Flags: Fragment;+++[H3BPQ2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455420}; Flags: Fragment;+++[H3BQB5_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455697}; Flags: Fragment;+++[H3BQH2_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000455779}; Flags: Fragment;+++[H3BR78_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456110}; Flags: Fragment;+++[H3BSM4_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000456772}; Flags: Fragment;+++[H3BUU9_HUMAN|Unreviewed]SubName: Full=Cadherin-11 {ECO:0000313|Ensembl:ENSP00000457812};+++[Q96CZ9_HUMAN|Unreviewed]SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast) {ECO:0000313|EMBL:AAH13609.1}; SubName: Full=Cadherin 11, type 2, OB-cadherin (Osteoblast), isoform CRA_c {ECO:0000313|EMBL:EAW83002.1};"]
[10090,"'UST'",30,35,32.5,"00532///Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0050770///regulation of axonogenesis+++GO:0006477///protein sulfation+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0030010///establishment of cell polarity","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR007734///Heparan sulphate 2-O-sulfotransferase+++IPR005331///Sulfotransferase","[UST_HUMAN|Reviewed]RecName: Full=Uronyl 2-sulfotransferase; EC=2.8.2.-;"]
[10092,"'ARPC5'",2200,1914,2057,"05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++04144///Endocytosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0034774///secretory granule lumen+++GO:0015629///actin cytoskeleton+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005885///Arp2/3 protein complex","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0030036///actin cytoskeleton organization+++GO:0030011///maintenance of cell polarity+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0051639///actin filament network formation+++GO:0016477///cell migration+++GO:0061024///membrane organization+++GO:0097581///lamellipodium organization+++GO:0061842///microtubule organizing center localization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0043312///neutrophil degranulation+++GO:0014909///smooth muscle cell migration+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0021769///orbitofrontal cortex development","IPR036743///Actin-related protein 2/3 complex subunit 5 superfamily+++IPR006789///Actin-related protein 2/3 complex subunit 5","[ARPC5_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5; AltName: Full=Arp2/3 complex 16 kDa subunit; Short=p16-ARC;+++[B1ALC0_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};+++[Q6IPM3_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 5 {ECO:0000256|RuleBase:RU004301};"]
[10093,"'ARPC4'",2331.15,1910.65,2120.9,"04144///Endocytosis+++05131///Shigellosis+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton","GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0051015///actin filament binding+++GO:0030674///protein binding, bridging+++GO:0003779///actin binding","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0045010///actin nucleation+++GO:0030041///actin filament polymerization+++GO:0048013///ephrin receptor signaling pathway+++GO:0061024///membrane organization+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis","IPR008384///Actin-related protein 2/3 complex subunit 4+++IPR034666///Arp2/3 complex subunit 2/4","[ARPC4_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 4; AltName: Full=Arp2/3 complex 20 kDa subunit; Short=p20-ARC;+++[F8WDD7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000395085};+++[F8WDW3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000414751};+++[R4GN08_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 4 {ECO:0000313|Ensembl:ENSP00000473435}; Flags: Fragment;"]
[10094,"'ARPC3'",2088,1502,1795,"05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++04144///Endocytosis+++05131///Shigellosis+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0031941///filamentous actin+++GO:0061850///growth cone leading edge+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0031252///cell leading edge+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton","GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0070358///actin polymerization-dependent cell motility","IPR007204///Actin-related protein 2/3 complex subunit 3+++IPR036753///Actin-related protein 2/3 complex subunit 3 superfamily","[ARPC3_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3; AltName: Full=Arp2/3 complex 21 kDa subunit; Short=p21-ARC;+++[C9JZD1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000413221}; Flags: Fragment;+++[F8VR50_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000313|Ensembl:ENSP00000446598}; Flags: Fragment;+++[Q2LE71_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit 3 {ECO:0000256|PIRNR:PIRNR016315}; AltName: Full=Arp2/3 complex 21 kDa subunit {ECO:0000256|PIRNR:PIRNR016315};"]
[10095,"'ARPC1B'",1838,1239,1538.5,"05131///Shigellosis+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection",{"$nulls":3},"GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0005925///focal adhesion+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0036284///tubulobulbar complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0044877///protein-containing complex binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0032355///response to estradiol+++GO:0043627///response to estrogen+++GO:0048013///ephrin receptor signaling pathway+++GO:0030833///regulation of actin filament polymerization","IPR017986///WD40-repeat-containing domain+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR030141///Actin-related protein 2/3 complex subunit 1B+++IPR017383///Actin-related protein 2/3 complex subunit 1+++IPR036322///WD40-repeat-containing domain superfamily+++IPR001680///WD40 repeat","[ARC1B_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1B; AltName: Full=Arp2/3 complex 41 kDa subunit; AltName: Full=p41-ARC;+++[A4D275_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};+++[C9J4Z7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000410238}; Flags: Fragment;+++[C9J6C8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398110}; Flags: Fragment;+++[C9JBJ7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000398620}; Flags: Fragment;+++[C9JEY1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403324}; Flags: Fragment;+++[C9JFG9_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000403211}; Flags: Fragment;+++[C9JM51_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408758}; Flags: Fragment;+++[C9JQM8_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000388802}; Flags: Fragment;+++[C9JTT6_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413067}; Flags: Fragment;+++[C9K057_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000413173};+++[F8VXW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000399955};+++[F8WEB3_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1B {ECO:0000313|Ensembl:ENSP00000408508};+++[L8EAG6_HUMAN|Unreviewed]SubName: Full=Alternative protein ARPC1B {ECO:0000313|EMBL:CCQ43333.1};"]
[10096,"'ACTR3'",3069,3296,3182.5,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0035861///site of double-strand break+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0005885///Arp2/3 protein complex+++GO:0030027///lamellipodium+++GO:0005911///cell-cell junction","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0005524///ATP binding+++GO:0003779///actin binding","GO:0007163///establishment or maintenance of cell polarity+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0071346///cellular response to interferon-gamma+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0070358///actin polymerization-dependent cell motility+++GO:0008356///asymmetric cell division+++GO:0060271///cilium assembly+++GO:0033206///meiotic cytokinesis+++GO:0007015///actin filament organization+++GO:0061024///membrane organization+++GO:0051321///meiotic cell cycle+++GO:0051653///spindle localization+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0048013///ephrin receptor signaling pathway+++GO:0030030///cell projection organization","IPR015623///Actin-related protein 3+++IPR020902///Actin/actin-like conserved site+++IPR004000///Actin family","[ARP3_HUMAN|Reviewed]RecName: Full=Actin-related protein 3; AltName: Full=Actin-like protein 3;+++[A0A024RAI1_HUMAN|Unreviewed]SubName: Full=ARP3 actin-related protein 3 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW95180.1};+++[B4DXW1_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000444987}; SubName: Full=cDNA FLJ51148, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63684.1}; SubName: Full=cDNA FLJ52434, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAG63523.1}; SubName: Full=cDNA, FLJ79112, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14584.1}; SubName: Full=cDNA, FLJ79295, highly similar to Actin-like protein 3 {ECO:0000313|EMBL:BAH14767.1};+++[F8WDR7_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000403125}; Flags: Fragment;+++[F8WE84_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000394213};+++[F8WEW2_HUMAN|Unreviewed]SubName: Full=Actin-related protein 3 {ECO:0000313|Ensembl:ENSP00000407912};"]
[10097,"'ACTR2'",2349,3183,2766,"04530///Tight junction+++04138///Autophagy - yeast",{"$nulls":3},"GO:0014069///postsynaptic density+++GO:0035861///site of double-strand break+++GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071437///invadopodium+++GO:0030027///lamellipodium+++GO:0005856///cytoskeleton+++GO:0035578///azurophil granule lumen+++GO:0098794///postsynapse+++GO:0061825///podosome core+++GO:0005885///Arp2/3 protein complex+++GO:0070062///extracellular exosome+++GO:0015629///actin cytoskeleton+++GO:0042995///cell projection+++GO:0030478///actin cap","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0051015///actin filament binding+++GO:0008092///cytoskeletal protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0061024///membrane organization+++GO:0033206///meiotic cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:1905168///positive regulation of double-strand break repair via homologous recombination+++GO:0007015///actin filament organization+++GO:0043312///neutrophil degranulation+++GO:0008306///associative learning+++GO:0035902///response to immobilization stress+++GO:0045471///response to ethanol+++GO:0016482///cytosolic transport+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0008356///asymmetric cell division+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining+++GO:0007163///establishment or maintenance of cell polarity+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0016344///meiotic chromosome movement towards spindle pole+++GO:0060271///cilium assembly+++GO:0051321///meiotic cell cycle+++GO:0035984///cellular response to trichostatin A+++GO:0071346///cellular response to interferon-gamma+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0051653///spindle localization","IPR027306///Actin-related protein 2+++IPR004000///Actin family+++IPR020902///Actin/actin-like conserved site","[ARP2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2; AltName: Full=Actin-like protein 2;+++[A0A1B0GWD0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490877};+++[A0A1B0GWH0_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000490923};+++[F5H6T1_HUMAN|Unreviewed]SubName: Full=ARP2 actin-related protein 2 homolog (Yeast), isoform CRA_d {ECO:0000313|EMBL:EAW99914.1}; SubName: Full=Actin-related protein 2 {ECO:0000313|Ensembl:ENSP00000437383};+++[Q8IY98_HUMAN|Unreviewed]SubName: Full=ACTR2 protein {ECO:0000313|EMBL:AAH36253.1};"]
[10098,"'TSPAN5'",380,403,391.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0019899///enzyme binding","GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane+++GO:0007166///cell surface receptor signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0045747///positive regulation of Notch signaling pathway","IPR008952///Tetraspanin, EC2 domain superfamily+++IPR000301///Tetraspanin+++IPR018503///Tetraspanin, conserved site+++IPR018499///Tetraspanin/Peripherin","[TSN5_HUMAN|Reviewed]RecName: Full=Tetraspanin-5; Short=Tspan-5; AltName: Full=Tetraspan NET-4; AltName: Full=Transmembrane 4 superfamily member 9;+++[B7Z317_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[D6R9N6_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000423504}; Flags: Fragment;+++[D6RAR1_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000421808};+++[D6RBT5_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422548};+++[D6RGZ7_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000426248}; Flags: Fragment;+++[H0Y8W4_HUMAN|Unreviewed]SubName: Full=Tetraspanin-5 {ECO:0000313|Ensembl:ENSP00000422351}; Flags: Fragment;+++[Q6FHC5_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[10099,"'TSPAN3'",4071,3662,3866.5,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway","H00287///Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome",null,null,"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0007166///cell surface receptor signaling pathway+++GO:0008150///biological_process","IPR008952///Tetraspanin, EC2 domain superfamily+++IPR000301///Tetraspanin+++IPR018503///Tetraspanin, conserved site+++IPR018499///Tetraspanin/Peripherin","[TSN3_HUMAN|Reviewed]RecName: Full=Tetraspanin-3; Short=Tspan-3; AltName: Full=Tetraspanin TM4-A; AltName: Full=Transmembrane 4 superfamily member 8;+++[H0YKJ9_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000452835};+++[H0YMH8_HUMAN|Unreviewed]SubName: Full=Tetraspanin-3 {ECO:0000313|Ensembl:ENSP00000453613};+++[L8E893_HUMAN|Unreviewed]SubName: Full=Alternative protein TSPAN3 {ECO:0000313|EMBL:CCQ43334.1};"]
[100996259,"'FAM106B'",7.58,7.09,7.335,{"$nulls":8},"[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[F106A_HUMAN|diamond]RecName: Full=Protein FAM106A;+++[F106C_HUMAN|diamond]RecName: Full=Putative protein FAM106C; AltName: Full=FAM106C pseudogene;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[100996318,"'LOC100996318'",16.01,11.45,13.73,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006334///nucleosome assembly","IPR009072///Histone-fold+++IPR007125///Histone H2A/H2B/H3+++IPR000558///Histone H2B","[H2B1_BOVIN|diamond]RecName: Full=Histone H2B type 1;+++[H2B1H_HUMAN|diamond]RecName: Full=Histone H2B type 1-H; AltName: Full=Histone H2B.j; Short=H2B/j;+++[H2B1O_HUMAN|diamond]RecName: Full=Histone H2B type 1-O; AltName: Full=Histone H2B.2; AltName: Full=Histone H2B.n; Short=H2B/n;+++[H2B2B_MOUSE|diamond]RecName: Full=Histone H2B type 2-B; AltName: Full=H2b 616;+++[H2B2F_HUMAN|diamond]RecName: Full=Histone H2B type 2-F;"]
[100996379,"'LOC100996379'",2,2.48,2.24,"04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal+++04137///Mitophagy - animal","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0032183///SUMO binding+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0007283///spermatogenesis+++GO:0006886///intracellular protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0016567///protein ubiquitination+++GO:0006974///cellular response to DNA damage stimulus","IPR006624///Beta-propeller repeat TECPR+++IPR014722///Ribosomal protein L2, domain 2+++IPR000433///Zinc finger, ZZ-type+++IPR004939///APC10/DOC domain+++IPR035983///HECT, E3 ligase catalytic domain+++IPR009091///Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II+++IPR008979///Galactose-binding-like domain superfamily+++IPR010606///Mib-herc2+++IPR037976///HERC2, APC10 domain+++IPR021097///CPH domain+++IPR000408///Regulator of chromosome condensation, RCC1+++IPR036400///Cytochrome b5-like heme/steroid binding domain superfamily+++IPR037252///Mib/herc2 domain superfamily+++IPR001199///Cytochrome b5-like heme/steroid binding domain+++IPR000569///HECT domain","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996414,"'100996414'",28.46,28.23,28.345,{"$nulls":7},"IPR031572///Domain of unknown function DUF4705","[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[100996485,"'C5orf66'",1,0,0.5,"05034///Alcoholism+++04140///Autophagy - animal+++04217///Necroptosis+++04137///Mitophagy - animal+++05322///Systemic lupus erythematosus","H00903///Congenital clubfoot",null,null,"GO:0070062///extracellular exosome+++GO:0000793///condensed chromosome+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0001739///sex chromatin+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005721///pericentric heterochromatin+++GO:0001740///Barr body+++GO:0005634///nucleus+++GO:0000786///nucleosome+++GO:0000790///nuclear chromatin+++GO:0000228///nuclear chromosome","GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0031492///nucleosomal DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0031490///chromatin DNA binding+++GO:0019901///protein kinase binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0010385///double-stranded methylated DNA binding+++GO:0019899///enzyme binding+++GO:1990841///promoter-specific chromatin binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0000182///rDNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding","GO:0035116///embryonic hindlimb morphogenesis+++GO:1902883///negative regulation of response to oxidative stress+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007549///dosage compensation+++GO:1902884///positive regulation of response to oxidative stress+++GO:0045814///negative regulation of gene expression, epigenetic+++GO:0006342///chromatin silencing+++GO:0001501///skeletal system development+++GO:0051216///cartilage development+++GO:1904815///negative regulation of protein localization to chromosome, telomeric region+++GO:0006355///regulation of transcription, DNA-templated+++GO:1902750///negative regulation of cell cycle G2/M phase transition+++GO:0071169///establishment of protein localization to chromatin+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0006351///transcription, DNA-templated+++GO:0034184///positive regulation of maintenance of mitotic sister chromatid cohesion+++GO:0019216///regulation of lipid metabolic process+++GO:0014707///branchiomeric skeletal muscle development+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0040029///regulation of gene expression, epigenetic+++GO:0051572///negative regulation of histone H3-K4 methylation+++GO:0061086///negative regulation of histone H3-K27 methylation+++GO:0033128///negative regulation of histone phosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0006334///nucleosome assembly+++GO:0048625///myoblast fate commitment+++GO:1901837///negative regulation of transcription of nucleolar large rRNA by RNA polymerase I+++GO:1902882///regulation of response to oxidative stress+++GO:0021983///pituitary gland development+++GO:0045618///positive regulation of keratinocyte differentiation","IPR001356///Homeobox domain+++IPR001909///Krueppel-associated box+++IPR020683///Ankyrin repeat-containing domain+++IPR009057///Homeobox-like domain superfamily+++IPR007125///Histone H2A/H2B/H3+++IPR016233///Homeobox protein Pitx/unc30+++IPR036236///Zinc finger C2H2 superfamily+++IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR017970///Homeobox, conserved site+++IPR003654///OAR domain+++IPR036051///KRAB domain superfamily+++IPR021171///Core histone macro-H2A+++IPR032454///Histone H2A, C-terminal domain+++IPR009072///Histone-fold+++IPR002589///Macro domain+++IPR002119///Histone H2A+++IPR035796///Core histone macro-H2A, macro domain+++IPR021939///Kank N-terminal motif","[CE066_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein C5orf66;"]
[100996517,"'SEC22B3'",237.71,319.84,278.775,"04145///Phagosome+++04130///SNARE interactions in vesicular transport+++05134///Legionellosis",{"$nulls":3},"GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000139///Golgi membrane+++GO:0042470///melanosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0031201///SNARE complex+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0008021///synaptic vesicle+++GO:0030133///transport vesicle","GO:0000149///SNARE binding+++GO:0019905///syntaxin binding+++GO:0005484///SNAP receptor activity","GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:1902902///negative regulation of autophagosome assembly+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0045732///positive regulation of protein catabolic process+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent","IPR010908///Longin domain+++IPR001388///Synaptobrevin+++IPR011012///Longin-like domain superfamily","[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996643,"'LOC100996643'",1,2,1.5,"00670///One carbon pool by folate+++04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005739///mitochondrion","GO:0008237///metallopeptidase activity+++GO:0016805///dipeptidase activity+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0005524///ATP binding+++GO:0015267///channel activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0008236///serine-type peptidase activity+++GO:0042803///protein homodimerization activity+++GO:0004180///carboxypeptidase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0050129///N-formylglutamate deformylase activity+++GO:0004329///formate-tetrahydrofolate ligase activity+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity","GO:0042135///neurotransmitter catabolic process+++GO:0006508///proteolysis+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0001843///neural tube closure+++GO:0006760///folic acid-containing compound metabolic process+++GO:0008652///cellular amino acid biosynthetic process+++GO:0048703///embryonic viscerocranium morphogenesis+++GO:0009113///purine nucleobase biosynthetic process+++GO:0046655///folic acid metabolic process+++GO:0015942///formate metabolic process+++GO:0035999///tetrahydrofolate interconversion+++GO:0009257///10-formyltetrahydrofolate biosynthetic process","IPR023271///Aquaporin-like+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR020631///Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain+++IPR000315///B-box-type zinc finger+++IPR000672///Tetrahydrofolate dehydrogenase/cyclohydrolase+++IPR001841///Zinc finger, RING-type+++IPR007484///Peptidase M28+++IPR039373///Glutamate carboxypeptidase 2-like+++IPR036757///Transferrin receptor-like, dimerisation domain superfamily+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR000425///Major intrinsic protein+++IPR017907///Zinc finger, RING-type, conserved site+++IPR003879///Butyrophylin-like, SPRY domain+++IPR020630///Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain+++IPR001870///B30.2/SPRY domain+++IPR003137///PA domain+++IPR007365///Transferrin receptor-like, dimerisation domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003877///SPRY domain+++IPR036291///NAD(P)-binding domain superfamily+++IPR000559///Formate-tetrahydrofolate ligase, FTHFS+++IPR019351///Protein of unknown function DUF2039+++IPR015686///Aquaporin 7+++IPR020628///Formate-tetrahydrofolate ligase, FTHFS, conserved site","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[TR43B_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43B;+++[TRI43_HUMAN|diamond]RecName: Full=Tripartite motif-containing protein 43;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[100996693,"'LOC100996693'",15,7,11,{"$nulls":7},"IPR000048///IQ motif, EF-hand binding site+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003598///Immunoglobulin subtype 2+++IPR013098///Immunoglobulin I-set+++IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain","[A0A087WV53_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000479190};"]
[100996709,"'LOC100996709'",113.96,112.43,113.195,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore","GO:0005525///GTP binding+++GO:0008270///zinc ion binding+++GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0004181///metallocarboxypeptidase activity+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)","GO:0043984///histone H4-K16 acetylation+++GO:0015031///protein transport+++GO:0035610///protein side chain deglutamylation+++GO:0043981///histone H4-K5 acetylation+++GO:0016192///vesicle-mediated transport+++GO:0043982///histone H4-K8 acetylation","IPR006689///Small GTPase superfamily, ARF/SAR type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR031687///ADP-ribosylation factor-like protein 17, C-terminal","[ARL17_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 17; AltName: Full=ADP-ribosylation factor 7 variant;+++[A0A087WY76_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000481578};+++[I3L1V5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000459131};+++[I3L3L1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 17 {ECO:0000313|Ensembl:ENSP00000460539};"]
[100996716,"'SEC22B2'",217.53,138.69,178.11,"04145///Phagosome+++05134///Legionellosis+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0030133///transport vesicle+++GO:0042470///melanosome+++GO:0030670///phagocytic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0031201///SNARE complex+++GO:0000139///Golgi membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005789///endoplasmic reticulum membrane+++GO:0005622///intracellular+++GO:0016021///integral component of membrane","GO:0005484///SNAP receptor activity+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0045732///positive regulation of protein catabolic process+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0015031///protein transport+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane","IPR012317///Poly(ADP-ribose) polymerase, catalytic domain+++IPR001388///Synaptobrevin+++IPR010908///Longin domain+++IPR011012///Longin-like domain superfamily","[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[SC22B_CRIGR|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B;+++[SC22B_HUMAN|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_MOUSE|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1; Short=mSec22b;+++[SC22B_PONAB|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[SC22B_RAT|diamond]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;"]
[100996717,"'NOTCH2NLC'",88.18,84.4,86.29,"01522///Endocrine resistance+++05224///Breast cancer+++04320///Dorso-ventral axis formation+++05200///Pathways in cancer+++04919///Thyroid hormone signaling pathway+++04658///Th1 and Th2 cell differentiation+++04330///Notch signaling pathway+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection","H00623///Hajdu-Cheney syndrome+++H00551///Alagille syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development+++GO:0045747///positive regulation of Notch signaling pathway","IPR000742///EGF-like domain+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR018097///EGF-like calcium-binding, conserved site+++IPR001881///EGF-like calcium-binding domain+++IPR013032///EGF-like, conserved site","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NC_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[100996720,"'LOC100996720'",191,131,161,{"$nulls":4},"GO:0005622///intracellular","GO:0003950///NAD+ ADP-ribosyltransferase activity",null,"IPR012317///Poly(ADP-ribose) polymerase, catalytic domain","[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PARP8_HUMAN|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;+++[PARP8_MOUSE|diamond]RecName: Full=Poly [ADP-ribose] polymerase 8; Short=PARP-8; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 16; Short=ARTD16;"]
[100996741,"'100996741'",41.46,46,43.73,{"$nulls":7},"IPR031773///Protein of unknown function DUF4741","[F231A_HUMAN|diamond]RecName: Full=Putative protein FAM231AP {ECO:0000305};+++[F231B_HUMAN|diamond]RecName: Full=Putative protein FAM231BP;+++[F231C_HUMAN|diamond]RecName: Full=Protein FAM231C;+++[F231D_HUMAN|diamond]RecName: Full=Protein FAM231D;+++[F231L_HUMAN|diamond]RecName: Full=FAM231A/C-like protein LOC102723383;"]
[100996746,"'SPDYE11'",0,1.97,0.985,"04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","IPR020984///Cell cycle regulatory protein Speedy","[SPD16_HUMAN|diamond]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[SPDE1_HUMAN|diamond]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;+++[SPDE2_HUMAN|diamond]RecName: Full=Speedy protein E2;+++[SPDE3_HUMAN|diamond]RecName: Full=Speedy protein E3;+++[SPDE6_HUMAN|diamond]RecName: Full=Speedy protein E6;+++[SPE2B_HUMAN|diamond]RecName: Full=Speedy protein E2B;"]
[100996747,"'LOC100996747'",193.57,131.76,162.665,{"$nulls":4},"GO:0042788///polysomal ribosome+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane+++GO:0022627///cytosolic small ribosomal subunit","GO:0003735///structural constituent of ribosome+++GO:0003729///mRNA binding","GO:0002181///cytoplasmic translation+++GO:0033119///negative regulation of RNA splicing","IPR038551///Ribosomal protein S26e superfamily+++IPR000892///Ribosomal protein S26e","[RS26_BOVIN|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_HUMAN|diamond]RecName: Full=40S ribosomal protein S26; AltName: Full=Small ribosomal subunit protein eS26 {ECO:0000303|PubMed:24524803};+++[RS26_MACFA|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_MOUSE|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_PIG|diamond]RecName: Full=40S ribosomal protein S26;+++[RS26_RAT|diamond]RecName: Full=40S ribosomal protein S26;"]
[100996758,"'NPY4R2'",7.08,0,3.54,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0001602///pancreatic polypeptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0017046///peptide hormone binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0007218///neuropeptide signaling pathway","IPR017452///GPCR, rhodopsin-like, 7TM+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR001933///Neuropeptide Y4 receptor+++IPR000611///Neuropeptide Y receptor family","[NPY4R_HUMAN|Reviewed]RecName: Full=Neuropeptide Y receptor type 4; Short=NPY4-R; AltName: Full=Pancreatic polypeptide receptor 1; Short=PP1;"]
[100996763,"'NOTCH2NLB'",88.3,97.67,92.985,"05200///Pathways in cancer+++04320///Dorso-ventral axis formation+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005112///Notch binding+++GO:0005515///protein binding","GO:0045747///positive regulation of Notch signaling pathway+++GO:0007219///Notch signaling pathway+++GO:0021987///cerebral cortex development","IPR018097///EGF-like calcium-binding, conserved site+++IPR000742///EGF-like domain+++IPR001881///EGF-like calcium-binding domain+++IPR013032///EGF-like, conserved site+++IPR000152///EGF-type aspartate/asparagine hydroxylation site","[NT2NA_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|Reviewed]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[A0A0B4J2B3_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 14 {ECO:0000313|Ensembl:ENSP00000472124};"]
[100996792,"'LOC100996792'",2.01,0,1.005,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0004713///protein tyrosine kinase activity+++GO:0005524///ATP binding+++GO:0004708///MAP kinase kinase activity+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity","GO:0031098///stress-activated protein kinase signaling cascade+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006954///inflammatory response+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0000187///activation of MAPK activity+++GO:0042981///regulation of apoptotic process+++GO:0045860///positive regulation of protein kinase activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060048///cardiac muscle contraction+++GO:0023014///signal transduction by protein phosphorylation+++GO:0007165///signal transduction+++GO:0038066///p38MAPK cascade+++GO:0032147///activation of protein kinase activity+++GO:0007346///regulation of mitotic cell cycle+++GO:0043536///positive regulation of blood vessel endothelial cell migration","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[MP2K3_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000269|PubMed:8622669}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3; AltName: Full=Stress-activated protein kinase kinase 2; Short=SAPK kinase 2; Short=SAPKK-2; Short=SAPKK2;+++[MP2K3_MOUSE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 3; Short=MAP kinase kinase 3; Short=MAPKK 3; EC=2.7.12.2 {ECO:0000250|UniProtKB:P46734}; AltName: Full=MAPK/ERK kinase 3; Short=MEK 3;+++[MP2K6_BOVIN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6;+++[MP2K6_DANRE|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAP kinase kinase 6 {ECO:0000250|UniProtKB:P52564}; Short=MAPKK 6 {ECO:0000250|UniProtKB:P52564}; EC=2.7.12.2; AltName: Full=Mitogen-activated protein kinase kinase 3 {ECO:0000303|PubMed:10995439}; Short=zMKK3 {ECO:0000312|EMBL:BAB11809.1};+++[MP2K6_HUMAN|diamond]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 6; Short=MAP kinase kinase 6; Short=MAPKK 6; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 6; Short=MEK 6; AltName: Full=Stress-activated protein kinase kinase 3; Short=SAPK kinase 3; Short=SAPKK-3; Short=SAPKK3;"]
[100996842,"'LOC100996842'",21,13,17,"04142///Lysosome",{"$nulls":3},"GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane",null,"GO:0043312///neutrophil degranulation+++GO:0071310///cellular response to organic substance","IPR018134///Lysosome-associated membrane glycoprotein, conserved site+++IPR002000///Lysosome-associated membrane glycoprotein","[CD68_HUMAN|diamond]RecName: Full=Macrosialin; AltName: Full=Gp110; AltName: CD_antigen=CD68; Flags: Precursor;+++[CD68_MOUSE|diamond]RecName: Full=Macrosialin; AltName: CD_antigen=CD68; Flags: Precursor;+++[MPU1_CRIGR|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation; Short=SL15;+++[MPU1_HUMAN|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;+++[MPU1_MOUSE|diamond]RecName: Full=Mannose-P-dolichol utilization defect 1 protein; AltName: Full=Suppressor of Lec15 and Lec35 glycosylation mutation homolog; Short=SL15;"]
[100996911,"'LOC100996911'",3.34,1,2.17,{"$nulls":4},"GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0031258///lamellipodium membrane+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0043202///lysosomal lumen+++GO:0005576///extracellular region+++GO:0016324///apical plasma membrane+++GO:0005796///Golgi lumen+++GO:0062023///collagen-containing extracellular matrix","GO:0019901///protein kinase binding","GO:0035556///intracellular signal transduction+++GO:0000187///activation of MAPK activity+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0008283///cell proliferation+++GO:0048771///tissue remodeling+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030207///chondroitin sulfate catabolic process+++GO:0008347///glial cell migration+++GO:0001525///angiogenesis+++GO:0030208///dermatan sulfate biosynthetic process","IPR039005///CSPG repeat+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR001791///Laminin G domain","[A0A024R018_HUMAN|Unreviewed]SubName: Full=HCG1818167, isoform CRA_a {ECO:0000313|EMBL:EAW55850.1};"]
[100996928,"'C7orf55-LUC7L2'",0,7.83,3.915,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0071004///U2-type prespliceosome+++GO:0005685///U1 snRNP+++GO:0016607///nuclear speck+++GO:0005739///mitochondrion","GO:0003729///mRNA binding+++GO:0019899///enzyme binding+++GO:0003723///RNA binding","GO:0050995///negative regulation of lipid catabolic process+++GO:0006376///mRNA splice site selection+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly","IPR004882///Luc7-related+++IPR037667///Protein FMC1 homologue","[FMC1_HUMAN|Reviewed]RecName: Full=Protein FMC1 homolog; AltName: Full=ATP synthase assembly factor FMC1, mitochondrial {ECO:0000312|HGNC:HGNC:26946}; AltName: Full=Formation of mitochondrial complex V assembly factor 1 homolog {ECO:0000312|HGNC:HGNC:26946};+++[A0A0A6YYJ8_HUMAN|Unreviewed]SubName: Full=Putative RNA-binding protein Luc7-like 2 {ECO:0000313|Ensembl:ENSP00000440222};"]
[100996939,"'PYURF'",343,257,300,"00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis+++01100///Metabolic pathways","H01488///Hyperphosphatasia with mental retardation syndrome (HPMPS)+++H01489///Inherited glycosylphosphatidylinositol (GPI) deficiencies",null,"R05916///UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143","GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0009893///positive regulation of metabolic process+++GO:0006506///GPI anchor biosynthetic process","IPR005651///Trm112-like","[PREY_HUMAN|Reviewed]RecName: Full=Protein preY, mitochondrial; AltName: Full=PIGY upstream reading frame protein; Flags: Precursor;"]
[101,"'ADAM8'",18,10,14,{"$nulls":4},"GO:0070821///tertiary granule membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0042581///specific granule+++GO:0032127///dense core granule membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0032010///phagolysosome+++GO:0016020///membrane+++GO:0070820///tertiary granule+++GO:0071065///alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex+++GO:0009986///cell surface+++GO:0005737///cytoplasm+++GO:0002102///podosome+++GO:0035579///specific granule membrane+++GO:0071133///alpha9-beta1 integrin-ADAM8 complex","GO:0008237///metallopeptidase activity+++GO:0050839///cell adhesion molecule binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0043621///protein self-association","GO:0071456///cellular response to hypoxia+++GO:0006508///proteolysis+++GO:0006954///inflammatory response+++GO:2000418///positive regulation of eosinophil migration+++GO:0043406///positive regulation of MAP kinase activity+++GO:0050714///positive regulation of protein secretion+++GO:0002523///leukocyte migration involved in inflammatory response+++GO:0070245///positive regulation of thymocyte apoptotic process+++GO:0045780///positive regulation of bone resorption+++GO:2000415///positive regulation of fibronectin-dependent thymocyte migration+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0001525///angiogenesis+++GO:0045089///positive regulation of innate immune response+++GO:0022617///extracellular matrix disassembly+++GO:0002693///positive regulation of cellular extravasation+++GO:2000406///positive regulation of T cell migration+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:2000309///positive regulation of tumor necrosis factor (ligand) superfamily member 11 production+++GO:0010954///positive regulation of protein processing+++GO:0043312///neutrophil degranulation+++GO:0050729///positive regulation of inflammatory response+++GO:0002675///positive regulation of acute inflammatory response+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045785///positive regulation of cell adhesion+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0098609///cell-cell adhesion+++GO:0007229///integrin-mediated signaling pathway+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0048247///lymphocyte chemotaxis+++GO:0000902///cell morphogenesis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0022407///regulation of cell-cell adhesion","IPR036436///Disintegrin domain superfamily+++IPR018358///Disintegrin, conserved site+++IPR001762///Disintegrin domain+++IPR013032///EGF-like, conserved site+++IPR001590///Peptidase M12B, ADAM/reprolysin+++IPR034027///Reprolysin domain, adamalysin-type+++IPR006586///ADAM, cysteine-rich+++IPR002870///Peptidase M12B, propeptide+++IPR024079///Metallopeptidase, catalytic domain superfamily+++IPR000742///EGF-like domain","[ADAM8_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 8; Short=ADAM 8; EC=3.4.24.-; AltName: Full=Cell surface antigen MS2; AltName: CD_antigen=CD156a; Flags: Precursor;+++[H0YKZ1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000452994};+++[H0YMT6_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000453735}; Flags: Fragment;+++[Q14C66_HUMAN|Unreviewed]SubName: Full=ADAM8 protein {ECO:0000313|EMBL:AAI15405.1}; SubName: Full=cDNA, FLJ93272, highly similar to Homo sapiens a disintegrin and metalloproteinase domain 8 (ADAM8),mRNA {ECO:0000313|EMBL:BAG35688.1};"]
[10100,"'TSPAN2'",319,425,372,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0007166///cell surface receptor signaling pathway+++GO:0048709///oligodendrocyte differentiation+++GO:0014005///microglia development+++GO:0014002///astrocyte development+++GO:0006954///inflammatory response+++GO:0042552///myelination+++GO:0061564///axon development+++GO:0007420///brain development","IPR000301///Tetraspanin+++IPR018503///Tetraspanin, conserved site+++IPR018499///Tetraspanin/Peripherin+++IPR008952///Tetraspanin, EC2 domain superfamily","[TSN2_HUMAN|Reviewed]RecName: Full=Tetraspanin-2; Short=Tspan-2; AltName: Full=Tetraspan NET-3;+++[B1AKP1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[B1AKP2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[B2RD31_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};"]
[10101,"'NUBP2'",1056,724,890,"03460///Fanconi anemia pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0031616///spindle pole centrosome+++GO:0005929///cilium+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0000166///nucleotide binding+++GO:0051536///iron-sulfur cluster binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0051642///centrosome localization+++GO:0001558///regulation of cell growth+++GO:0030030///cell projection organization+++GO:0006879///cellular iron ion homeostasis+++GO:0010826///negative regulation of centrosome duplication+++GO:0016226///iron-sulfur cluster assembly+++GO:0072697///protein localization to cell cortex","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR028600///Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes+++IPR000808///Mrp, conserved site+++IPR019591///Mrp/NBP35 ATP-binding protein+++IPR033756///Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35","[NUBP2_HUMAN|Reviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000255|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000255|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000255|HAMAP-Rule:MF_03039};+++[B2RDN3_HUMAN|Unreviewed]RecName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000256|HAMAP-Rule:MF_03039}; AltName: Full=Nucleotide-binding protein 2 {ECO:0000256|HAMAP-Rule:MF_03039}; Short=NBP 2 {ECO:0000256|HAMAP-Rule:MF_03039};+++[B7Z6P0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000460079}; SubName: Full=Nucleotide binding protein 2 (MinD homolog, E. coli), isoform CRA_d {ECO:0000313|EMBL:EAW85616.1}; SubName: Full=cDNA FLJ57200, highly similar to Nucleotide-binding protein 2 {ECO:0000313|EMBL:BAH13326.1};+++[H3BMW1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454576}; Flags: Fragment;+++[H3BNF0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454815};+++[H3BNS4_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000454982}; Flags: Fragment;+++[H3BQE5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455739}; Flags: Fragment;+++[H3BQR2_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000455896};+++[H3BRE1_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456199}; Flags: Fragment;+++[H3BRK5_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000313|Ensembl:ENSP00000456284};+++[I3L3A0_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000460288}; Flags: Fragment;+++[I3L518_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461723}; Flags: Fragment;+++[I3L531_HUMAN|Unreviewed]SubName: Full=Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000313|Ensembl:ENSP00000461746}; Flags: Fragment;+++[Q2YS46_HUMAN|Unreviewed]SubName: Full=C447E6.1 (Nucleotide binding protein 1 (E.coli MinD like) ) {ECO:0000313|EMBL:CAC36077.1}; Flags: Fragment;"]
[10102,"'TSFM'",210,161,185.5,null,"H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0003746///translation elongation factor activity+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0006414///translational elongation+++GO:0070129///regulation of mitochondrial translation+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","IPR014039///Translation elongation factor EFTs/EF1B, dimerisation+++IPR036402///Elongation factor Ts, dimerisation domain superfamily+++IPR018101///Translation elongation factor Ts, conserved site+++IPR001816///Translation elongation factor EFTs/EF1B+++IPR009060///UBA-like superfamily","[EFTS_HUMAN|Reviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000255|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000255|HAMAP-Rule:MF_03135}; Flags: Precursor;+++[B4DHY8_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[C9JG32_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000390679}; Flags: Fragment;+++[C9JT21_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000389162}; Flags: Fragment;+++[E5KS95_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VPA7_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8VS27_HUMAN|Unreviewed]RecName: Full=Elongation factor Ts, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-Ts {ECO:0000256|HAMAP-Rule:MF_03135}; Short=EF-TsMt {ECO:0000256|HAMAP-Rule:MF_03135};+++[F8WCK2_HUMAN|Unreviewed]SubName: Full=Elongation factor Ts, mitochondrial {ECO:0000313|Ensembl:ENSP00000406339};"]
[10103,"'TSPAN1'",37,33,35,"04213///Longevity regulating pathway - multiple species+++04071///Sphingolipid signaling pathway+++04218///Cellular senescence+++05166///HTLV-I infection+++04360///Axon guidance+++05161///Hepatitis B+++05212///Pancreatic cancer+++05164///Influenza A+++04666///Fc gamma R-mediated phagocytosis+++05162///Measles+++01521///EGFR tyrosine kinase inhibitor resistance+++04211///Longevity regulating pathway+++05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++04931///Insulin resistance+++05225///Hepatocellular carcinoma+++05146///Amoebiasis+++05165///Human papillomavirus infection+++04910///Insulin signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04150///mTOR signaling pathway+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++05226///Gastric cancer+++05221///Acute myeloid leukemia+++04660///T cell receptor signaling pathway+++05205///Proteoglycans in cancer+++04722///Neurotrophin signaling pathway+++05210///Colorectal cancer+++04750///Inflammatory mediator regulation of TRP channels+++04072///Phospholipase D signaling pathway+++04917///Prolactin signaling pathway+++05213///Endometrial cancer+++05220///Chronic myeloid leukemia+++04152///AMPK signaling pathway+++04926///Relaxin signaling pathway+++05223///Non-small cell lung cancer+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04210///Apoptosis+++04630///Jak-STAT signaling pathway+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++05418///Fluid shear stress and atherosclerosis+++05163///Human cytomegalovirus infection+++04810///Regulation of actin cytoskeleton+++04380///Osteoclast differentiation+++04012///ErbB signaling pathway+++04611///Platelet activation+++01524///Platinum drug resistance+++05160///Hepatitis C+++04014///Ras signaling pathway+++04625///C-type lectin receptor signaling pathway+++05215///Prostate cancer+++05222///Small cell lung cancer+++04070///Phosphatidylinositol signaling system+++05224///Breast cancer+++04510///Focal adhesion+++05231///Choline metabolism in cancer+++05203///Viral carcinogenesis+++04140///Autophagy - animal+++05230///Central carbon metabolism in cancer+++04930///Type II diabetes mellitus+++01522///Endocrine resistance+++04670///Leukocyte transendothelial migration+++04919///Thyroid hormone signaling pathway+++05218///Melanoma+++05142///Chagas disease (American trypanosomiasis)+++05214///Glioma+++04550///Signaling pathways regulating pluripotency of stem cells+++04370///VEGF signaling pathway+++04973///Carbohydrate digestion and absorption+++04062///Chemokine signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04650///Natural killer cell mediated cytotoxicity+++04620///Toll-like receptor signaling pathway+++04068///FoxO signaling pathway+++04915///Estrogen signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04024///cAMP signaling pathway+++04662///B cell receptor signaling pathway+++04664///Fc epsilon RI signaling pathway+++05169///Epstein-Barr virus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04725///Cholinergic synapse+++04960///Aldosterone-regulated sodium reabsorption","H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H01370///SHORT syndrome","M00676///PI3K-Akt signaling","R03362///ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate+++R04545///ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate <=> ADP + Phosphatidylinositol-3,4,5-trisphosphate+++R05795///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate","GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane+++GO:0031982///vesicle+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0045807///positive regulation of endocytosis+++GO:0007166///cell surface receptor signaling pathway+++GO:0050821///protein stabilization+++GO:0008283///cell proliferation+++GO:0016477///cell migration","IPR018503///Tetraspanin, conserved site+++IPR018499///Tetraspanin/Peripherin+++IPR008952///Tetraspanin, EC2 domain superfamily+++IPR000301///Tetraspanin","[TSN1_HUMAN|Reviewed]RecName: Full=Tetraspanin-1; Short=Tspan-1; AltName: Full=Tetraspan NET-1; AltName: Full=Tetraspanin TM4-C;"]
[10105,"'PPIF'",334,212,273,"04020///Calcium signaling pathway+++05016///Huntington's disease+++05145///Toxoplasmosis+++05012///Parkinson's disease+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005757///mitochondrial permeability transition pore complex+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005753///mitochondrial proton-transporting ATP synthase complex","GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0042277///peptide binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding","GO:0012501///programmed cell death+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:1902445///regulation of mitochondrial membrane permeability involved in programmed necrotic cell death+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0010939///regulation of necrotic cell death+++GO:0002931///response to ischemia+++GO:0043066///negative regulation of apoptotic process+++GO:0010849///regulation of proton-transporting ATPase activity, rotational mechanism+++GO:0006457///protein folding+++GO:0008637///apoptotic mitochondrial changes+++GO:0042981///regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0032780///negative regulation of ATPase activity+++GO:2000276///negative regulation of oxidative phosphorylation uncoupler activity+++GO:0071243///cellular response to arsenic-containing substance+++GO:0006979///response to oxidative stress+++GO:1902686///mitochondrial outer membrane permeabilization involved in programmed cell death+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0090324///negative regulation of oxidative phosphorylation+++GO:0071277///cellular response to calcium ion+++GO:0070301///cellular response to hydrogen peroxide+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0070266///necroptotic process+++GO:0090200///positive regulation of release of cytochrome c from mitochondria","IPR002130///Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain+++IPR020892///Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site+++IPR024936///Cyclophilin-type peptidyl-prolyl cis-trans isomerase+++IPR029000///Cyclophilin-like domain superfamily","[PPIF_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase F, mitochondrial; Short=PPIase F; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Cyclophilin D; Short=CyP-D; Short=CypD; AltName: Full=Cyclophilin F; AltName: Full=Mitochondrial cyclophilin; Short=CyP-M; AltName: Full=Rotamase F; Flags: Precursor;+++[A0A024QZS4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[H0Y548_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[R4GN99_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[101059906,"'LOC101059906'",4,11,7.5,"01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,null,"R07376///L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0098978///glutamatergic synapse+++GO:0000139///Golgi membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol","GO:0019003///GDP binding+++GO:0016740///transferase activity+++GO:0003924///GTPase activity+++GO:0003882///CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0005525///GTP binding+++GO:0008022///protein C-terminus binding","GO:0071480///cellular response to gamma radiation+++GO:0090303///positive regulation of wound healing+++GO:0048013///ephrin receptor signaling pathway+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0007093///mitotic cell cycle checkpoint+++GO:0007265///Ras protein signal transduction+++GO:0051291///protein heterooligomerization+++GO:0034260///negative regulation of GTPase activity+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0042088///T-helper 1 type immune response+++GO:0043406///positive regulation of MAP kinase activity+++GO:0006897///endocytosis+++GO:0043547///positive regulation of GTPase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0010629///negative regulation of gene expression+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008284///positive regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:2000630///positive regulation of miRNA metabolic process+++GO:0046330///positive regulation of JNK cascade+++GO:0008283///cell proliferation+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0006935///chemotaxis+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1900029///positive regulation of ruffle assembly+++GO:0007165///signal transduction+++GO:0000165///MAPK cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0009887///animal organ morphogenesis+++GO:0090398///cellular senescence+++GO:0035900///response to isolation stress+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0007166///cell surface receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0010863///positive regulation of phospholipase C activity+++GO:0050852///T cell receptor signaling pathway+++GO:0042832///defense response to protozoan+++GO:0045740///positive regulation of DNA replication+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0032729///positive regulation of interferon-gamma production+++GO:0007050///cell cycle arrest+++GO:0001934///positive regulation of protein phosphorylation+++GO:0043524///negative regulation of neuron apoptotic process","IPR005225///Small GTP-binding protein domain+++IPR001611///Leucine-rich repeat+++IPR001806///Small GTPase+++IPR020849///Small GTPase superfamily, Ras-type+++IPR004277///Phosphatidyl serine synthase+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR032675///Leucine-rich repeat domain superfamily","[CO3A1_CHICK|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor; Fragments;+++[CO3A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(IV) chain; Contains: RecName: Full=Arresten; Flags: Precursor;+++[CO7A1_MOUSE|diamond]RecName: Full=Collagen alpha-1(VII) chain; AltName: Full=Long-chain collagen; Short=LC collagen; Flags: Precursor;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[LRC56_HUMAN|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_MOUSE|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[LRC56_RAT|diamond]RecName: Full=Leucine-rich repeat-containing protein 56;+++[PTSS2_CHICK|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_CRIGR|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_HUMAN|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_MOUSE|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[PTSS2_RAT|diamond]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[RASH_CHICK|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_HUMAN|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Ha-Ras; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_MOUSE|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASH_RAT|diamond]RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor;+++[RASK_KRYMA|diamond]RecName: Full=GTPase KRas; AltName: Full=Ki-Ras; Short=K-ras; Flags: Precursor;+++[RASK_MONDO|diamond]RecName: Full=GTPase KRas; AltName: Full=K-Ras 2; AltName: Full=Ki-Ras; AltName: Full=c-K-ras; AltName: Full=c-Ki-ras; Contains: RecName: Full=GTPase KRas, N-terminally processed; Flags: Precursor;+++[RINI_HUMAN|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Placental ribonuclease inhibitor; Short=Placental RNase inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1; Short=RAI;+++[RINI_PANTR|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_PIG|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[RINI_RAT|diamond]RecName: Full=Ribonuclease inhibitor; AltName: Full=Ribonuclease/angiogenin inhibitor 1;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[101059918,"'GOLGA8R'",13.74,3.42,8.58,"04530///Tight junction",{"$nulls":3},"GO:0005794///Golgi apparatus",null,null,"IPR024858///Golgin subfamily A","[GOG8R_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 8R;"]
[101059938,"'NPIPA7'",1637.95,1446.1,1542.025,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"IPR009443///Nuclear pore complex interacting protein","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0Y2X3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A7 {ECO:0000313|Ensembl:ENSP00000343256}; Flags: Fragment;"]
[101059949,"'LOC101059949'",11.06,7.08,9.07,{"$nulls":7},"IPR039497///CCDC144C-like, coiled-coil domain","[A2012_HUMAN|diamond]RecName: Full=Putative ankyrin repeat domain-containing protein 20A12 pseudogene {ECO:0000305};+++[AN18A_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18A;+++[AN18B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18B;+++[ANR26_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000305};+++[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;"]
[101059953,"'NPIPA8'",260.39,332.92,296.655,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"IPR009443///Nuclear pore complex interacting protein","[NPIA7_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[H0YFN8_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member A8 {ECO:0000313|Ensembl:ENSP00000439498}; Flags: Fragment;"]
[10106,"'CTDSP2'",706,919,812.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0016791///phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0016311///dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle","IPR040078///CTD small RNA polymerase II polypeptide A phosphatase-like+++IPR011948///Dullard phosphatase domain, eukaryotic+++IPR036412///HAD-like superfamily+++IPR004274///FCP1 homology domain+++IPR023214///HAD superfamily","[CTDS2_HUMAN|Reviewed]RecName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; EC=3.1.3.16; AltName: Full=Nuclear LIM interactor-interacting factor 2; Short=NLI-interacting factor 2; AltName: Full=Protein OS-4; AltName: Full=Small C-terminal domain phosphatase 2; AltName: Full=Small CTD phosphatase 2; Short=SCP2;+++[A0A024RB65_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_b {ECO:0000313|EMBL:EAW97086.1};+++[A0A024RBA6_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2, isoform CRA_c {ECO:0000313|EMBL:EAW97089.1};+++[F8VYL0_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448951};+++[F8W184_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000446705};+++[F8W1I1_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000447046};+++[H0YI12_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448299}; Flags: Fragment;+++[H0YI29_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 {ECO:0000313|Ensembl:ENSP00000448386}; Flags: Fragment;"]
[101060022,"'LOC101060022'",321.85,448.43,385.14,{"$nulls":7},"IPR031572///Domain of unknown function DUF4705","[PRR36_HUMAN|diamond]RecName: Full=Proline-rich protein 36 {ECO:0000312|HGNC:HGNC:26172};+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[101060179,"'LOC101060179'",60,58,59,{"$nulls":8},"[A0A2J8LHJ5_PANTR|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNI46744.1}; Flags: Fragment;+++[A0A2J8WFF8_PONAB|diamond]SubName: Full=PRDM11 isoform 5 {ECO:0000313|EMBL:PNJ68516.1}; Flags: Fragment;+++[A0A2R8MD89_CALJA|diamond]SubName: Full=PR/SET domain 11 {ECO:0000313|Ensembl:ENSCJAP00000057788};+++[H3BSZ2_HUMAN|diamond]SubName: Full=PR domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000456942}; Flags: Fragment;+++[Q8N1K6_HUMAN|diamond]SubName: Full=cDNA FLJ40559 fis, clone THYMU2002910 {ECO:0000313|EMBL:BAC05192.1};"]
[101060200,"'ZNF891'",11,6,8.5,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily","[ZN891_HUMAN|Reviewed]RecName: Full=Zinc finger protein 891;"]
[101060226,"'NBPF19'",276.73,341.64,309.185,"05224///Breast cancer+++01522///Endocrine resistance+++04137///Mitophagy - animal+++04330///Notch signaling pathway+++05200///Pathways in cancer+++04140///Autophagy - animal+++04320///Dorso-ventral axis formation+++04658///Th1 and Th2 cell differentiation+++05206///MicroRNAs in cancer+++05165///Human papillomavirus infection+++04919///Thyroid hormone signaling pathway","H00551///Alagille syndrome+++H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","IPR010630///Neuroblastoma breakpoint family (NBPF) domain","[NBPFJ_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};+++[A0A075B6G5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000358229};+++[A0A087X230_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484655};+++[A0A087X288_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000313|Ensembl:ENSP00000484787};"]
[101060233,"'OPN1MW3'",0,1,0.5,null,"H00976///Colorblindness+++H00974///Blue cone monochromacy",null,null,"GO:0005887///integral component of plasma membrane+++GO:0001750///photoreceptor outer segment+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008020///G protein-coupled photoreceptor activity+++GO:0009881///photoreceptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007601///visual perception+++GO:0071482///cellular response to light stimulus+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0009584///detection of visible light+++GO:0018298///protein-chromophore linkage+++GO:0050896///response to stimulus+++GO:0007602///phototransduction","IPR027430///Visual pigments (opsins) retinal binding site+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR001760///Opsin+++IPR000378///Opsin red/green sensitive+++IPR017452///GPCR, rhodopsin-like, 7TM","[OPSG2_HUMAN|Reviewed]RecName: Full=Medium-wave-sensitive opsin 2 {ECO:0000305}; AltName: Full=Green cone photoreceptor pigment {ECO:0000250|UniProtKB:P04001}; AltName: Full=Green-sensitive opsin {ECO:0000250|UniProtKB:P04001}; Short=GOP {ECO:0000250|UniProtKB:P04001}; AltName: Full=Opsin 1 cone pigments medium-wave-sensitive 2 {ECO:0000312|HGNC:HGNC:26952};+++[OPSG3_HUMAN|Reviewed]RecName: Full=Medium-wave-sensitive opsin 3; AltName: Full=Green cone photoreceptor pigment; AltName: Full=Green-sensitive opsin; Short=GOP; AltName: Full=opsin 1 cone pigments medium-wave-sensitive 3 {ECO:0000312|HGNC:HGNC:51831};+++[OPSG_HUMAN|Reviewed]RecName: Full=Medium-wave-sensitive opsin 1 {ECO:0000305}; AltName: Full=Green cone photoreceptor pigment; AltName: Full=Green-sensitive opsin; Short=GOP;"]
[101060254,"'LOC101060254'",41,44.1,42.55,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0030016///myofibril","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization+++GO:1903358///regulation of Golgi organization+++GO:0034622///cellular protein-containing complex assembly","IPR010630///Neuroblastoma breakpoint family (NBPF) domain+++IPR012943///Centrosomin, N-terminal motif 1","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_MOUSE|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[CK5P2_RAT|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFK_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 20;+++[NBPFP_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 26;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101060321,"'TBC1D3G'",0,57.38,28.69,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","IPR035969///Rab-GTPase-TBC domain superfamily+++IPR000195///Rab-GTPase-TBC domain","[TBC3C_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3C;+++[TBC3G_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3G;"]
[101060341,"'LOC101060341'",216.3,338.85,277.575,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR031572///Domain of unknown function DUF4705+++IPR019351///Protein of unknown function DUF2039","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101060351,"'TBC1D3K'",10.16,18.61,14.385,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","IPR000195///Rab-GTPase-TBC domain+++IPR035969///Rab-GTPase-TBC domain superfamily","[TBC3K_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3K {ECO:0000312|HGNC:HGNC:51245};+++[A0A0G2JPY0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3K {ECO:0000313|Ensembl:ENSP00000484542};"]
[101060376,"'TBC1D3L'",581.13,678.86,629.995,{"$nulls":4},"GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0005622///intracellular","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0031338///regulation of vesicle fusion+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","IPR000195///Rab-GTPase-TBC domain+++IPR035969///Rab-GTPase-TBC domain superfamily","[TBC3L_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3L {ECO:0000312|HGNC:HGNC:51246};+++[A0A0G2JP35_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 3L {ECO:0000313|Ensembl:ENSP00000482811};+++[B3KTC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38066 fis, clone CTONG2015330, highly similar to TBC1 domain family member 3 {ECO:0000313|EMBL:BAG53037.1};"]
[101060389,"'TBC1D3D'",26.66,54.39,40.525,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031901///early endosome membrane","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:1902017///regulation of cilium assembly+++GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","IPR000195///Rab-GTPase-TBC domain+++IPR035969///Rab-GTPase-TBC domain superfamily","[TBC3D_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3D {ECO:0000312|HGNC:HGNC:28944};"]
[101060684,"'NBPF26'",184.76,278.67,231.715,"04330///Notch signaling pathway+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++04140///Autophagy - animal+++05200///Pathways in cancer+++04137///Mitophagy - animal+++05165///Human papillomavirus infection+++04320///Dorso-ventral axis formation+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++01522///Endocrine resistance+++05206///MicroRNAs in cancer+++04658///Th1 and Th2 cell differentiation","H00551///Alagille syndrome+++H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++H00409///Type II diabetes mellitus+++H00623///Hajdu-Cheney syndrome","M00682///Notch signaling",null,"GO:0005737///cytoplasm","GO:0005509///calcium ion binding","GO:0007275///multicellular organism development+++GO:0007219///Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0050793///regulation of developmental process+++GO:0030154///cell differentiation","IPR010630///Neuroblastoma breakpoint family (NBPF) domain","[NBPFP_HUMAN|Reviewed]RecName: Full=Neuroblastoma breakpoint family member 26;+++[A0A075B7F9_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000476257};+++[A0A087WTG0_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000477847};+++[A0A087WU30_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000478334};+++[A0A087WVV8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000479721};+++[A0A087WWQ1_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000480416};+++[A0A087WY62_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000481542};+++[A0A087WZB6_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482516};+++[A0A087WZS8_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000482859};+++[A0A096LNW5_HUMAN|Unreviewed]SubName: Full=Neuroblastoma breakpoint family member 26 {ECO:0000313|Ensembl:ENSP00000485259};"]
[10109,"'ARPC2'",8662,6398,7530,"05132///Salmonella infection+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04810///Regulation of actin cytoskeleton+++05130///Pathogenic Escherichia coli infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005885///Arp2/3 protein complex+++GO:0005737///cytoplasm+++GO:0015629///actin cytoskeleton+++GO:0005925///focal adhesion+++GO:0036195///muscle cell projection membrane+++GO:0035861///site of double-strand break+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031252///cell leading edge+++GO:0030027///lamellipodium+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0045202///synapse","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0003779///actin binding","GO:0070358///actin polymerization-dependent cell motility+++GO:0048013///ephrin receptor signaling pathway+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0030041///actin filament polymerization+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0030833///regulation of actin filament polymerization+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0061024///membrane organization+++GO:0010592///positive regulation of lamellipodium assembly","IPR007188///Actin-related protein 2/3 complex subunit 2+++IPR034666///Arp2/3 complex subunit 2/4","[ARPC2_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 2; AltName: Full=Arp2/3 complex 34 kDa subunit; Short=p34-ARC;+++[A0A024R408_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[C9JTV5_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[G5E9J0_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};+++[G5E9S7_HUMAN|Unreviewed]SubName: Full=Actin related protein 2/3 complex, subunit 2, 34kDa, isoform CRA_e {ECO:0000313|EMBL:EAW70596.1}; SubName: Full=Actin-related protein 2/3 complex subunit 2 {ECO:0000313|Ensembl:ENSP00000412632};+++[H7C3F9_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015}; Flags: Fragment;+++[Q53R19_HUMAN|Unreviewed]RecName: Full=Arp2/3 complex 34 kDa subunit {ECO:0000256|RuleBase:RU364015};"]
[10110,"'SGK2'",0,3,1.5,"04068///FoxO signaling pathway+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular","GO:0005524///ATP binding+++GO:0017081///chloride channel regulator activity+++GO:0005246///calcium channel regulator activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0015459///potassium channel regulator activity+++GO:0017080///sodium channel regulator activity","GO:0018105///peptidyl-serine phosphorylation+++GO:0034220///ion transmembrane transport+++GO:0001558///regulation of cell growth+++GO:0032411///positive regulation of transporter activity+++GO:0006468///protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0006979///response to oxidative stress+++GO:0042127///regulation of cell proliferation","IPR008271///Serine/threonine-protein kinase, active site+++IPR000961///AGC-kinase, C-terminal+++IPR017441///Protein kinase, ATP binding site+++IPR017892///Protein kinase, C-terminal+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily","[SGK2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Sgk2; EC=2.7.11.1; AltName: Full=Serum/glucocorticoid-regulated kinase 2;"]
[10111,"'RAD50'",624,782,703,"03450///Non-homologous end-joining+++04218///Cellular senescence+++03440///Homologous recombination","H01344///Nijmegen syndrome","M00292///MRX complex+++M00291///MRN complex+++M00295///BRCA1-associated genome surveillance complex (BASC)",null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000790///nuclear chromatin+++GO:0030870///Mre11 complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus+++GO:0035861///site of double-strand break+++GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0008408///3'-5' exonuclease activity+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0051880///G-quadruplex DNA binding+++GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003691///double-stranded telomeric DNA binding+++GO:0004017///adenylate kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding+++GO:0043047///single-stranded telomeric DNA binding","GO:0016032///viral process+++GO:0033674///positive regulation of kinase activity+++GO:0006302///double-strand break repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007131///reciprocal meiotic recombination+++GO:0032206///positive regulation of telomere maintenance+++GO:0000019///regulation of mitotic recombination+++GO:0016233///telomere capping+++GO:0000723///telomere maintenance+++GO:0000722///telomere maintenance via recombination+++GO:0000729///DNA double-strand break processing+++GO:0007004///telomere maintenance via telomerase+++GO:0031860///telomeric 3' overhang formation+++GO:0032508///DNA duplex unwinding+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0000724///double-strand break repair via homologous recombination+++GO:1904354///negative regulation of telomere capping+++GO:0046940///nucleoside monophosphate phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0006281///DNA repair+++GO:0007049///cell cycle+++GO:0006260///DNA replication+++GO:0070192///chromosome organization involved in meiotic cell cycle","IPR013134///RAD50, zinc hook+++IPR038729///Rad50/SbcC-type AAA domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR004584///DNA repair protein Rad50, eukaryotes","[RAD50_HUMAN|Reviewed]RecName: Full=DNA repair protein RAD50; Short=hRAD50; EC=3.6.-.-;+++[A5D6Y3_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI40006.1}; Flags: Fragment;+++[C9JNH8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000389515}; Flags: Fragment;+++[E7EN38_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000400049}; Flags: Fragment;+++[E7ESD9_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000390971};+++[E9PM98_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000431225};+++[H7C0P8_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396100}; Flags: Fragment;+++[H7C0V2_HUMAN|Unreviewed]SubName: Full=DNA repair protein RAD50 {ECO:0000313|Ensembl:ENSP00000396860}; Flags: Fragment;+++[Q32P42_HUMAN|Unreviewed]SubName: Full=RAD50 protein {ECO:0000313|EMBL:AAI08283.1}; Flags: Fragment;"]
[10112,"'KIF20A'",0,5,2.5,{"$nulls":4},"GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005819///spindle+++GO:0045171///intercellular bridge+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005871///kinesin complex","GO:0005524///ATP binding+++GO:0016887///ATPase activity+++GO:0019901///protein kinase binding+++GO:0003777///microtubule motor activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0007018///microtubule-based movement+++GO:0032465///regulation of cytokinesis+++GO:0061952///midbody abscission+++GO:0000281///mitotic cytokinesis+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0001578///microtubule bundle formation","IPR001752///Kinesin motor domain+++IPR027326///Kinesin-like protein KIF20A+++IPR027640///Kinesin-like protein+++IPR019821///Kinesin motor domain, conserved site+++IPR036961///Kinesin motor domain superfamily+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[KI20A_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF20A; AltName: Full=GG10_2; AltName: Full=Mitotic kinesin-like protein 2; Short=MKlp2; AltName: Full=Rab6-interacting kinesin-like protein; AltName: Full=Rabkinesin-6;+++[D6R9E4_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000422928}; Flags: Fragment;+++[D6RBN1_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000424056}; Flags: Fragment;+++[H0YAC9_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF20A {ECO:0000313|Ensembl:ENSP00000426704}; Flags: Fragment;"]
[10113,"'PREB'",1370,1049,1209.5,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0005090///Sar guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0051020///GTPase binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0048208///COPII vesicle coating+++GO:0003400///regulation of COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0050790///regulation of catalytic activity+++GO:0009306///protein secretion+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0015031///protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0016192///vesicle-mediated transport","IPR017986///WD40-repeat-containing domain+++IPR036322///WD40-repeat-containing domain superfamily+++IPR011047///Quinoprotein alcohol dehydrogenase-like superfamily+++IPR001680///WD40 repeat","[PREB_HUMAN|Reviewed]RecName: Full=Prolactin regulatory element-binding protein; AltName: Full=Mammalian guanine nucleotide exchange factor mSec12;+++[A0A0F7RPZ8_HUMAN|Unreviewed]SubName: Full=Prometheus B {ECO:0000313|EMBL:CCP37866.1};+++[B5MC98_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000384032};+++[F8WCS5_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000416103};+++[H7BZX0_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000391894}; Flags: Fragment;+++[H7C0W3_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000397036}; Flags: Fragment;+++[H7C2N7_HUMAN|Unreviewed]SubName: Full=Prolactin regulatory element-binding protein {ECO:0000313|Ensembl:ENSP00000407036}; Flags: Fragment;+++[Q05DB2_HUMAN|Unreviewed]SubName: Full=PREB protein {ECO:0000313|EMBL:AAH16906.1}; SubName: Full=Prolactin regulatory element binding, isoform CRA_d {ECO:0000313|EMBL:EAX00629.1};"]
[10114,"'HIPK3'",433,737,585,"04218///Cellular senescence",{"$nulls":3},"GO:0005829///cytosol+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0018107///peptidyl-threonine phosphorylation+++GO:0009299///mRNA transcription+++GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0043508///negative regulation of JUN kinase activity+++GO:0006915///apoptotic process+++GO:0016310///phosphorylation","IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site","[HIPK3_HUMAN|Reviewed]RecName: Full=Homeodomain-interacting protein kinase 3; EC=2.7.11.1; AltName: Full=Androgen receptor-interacting nuclear protein kinase; Short=ANPK; AltName: Full=Fas-interacting serine/threonine-protein kinase; Short=FIST; AltName: Full=Homolog of protein kinase YAK1;+++[A8KAE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75520 {ECO:0000313|EMBL:BAF85698.1};+++[E9PKD7_HUMAN|Unreviewed]SubName: Full=Homeodomain-interacting protein kinase 3 {ECO:0000313|Ensembl:ENSP00000433594}; Flags: Fragment;"]
[10116,"'FEM1B'",299,253,276,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005123///death receptor binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:2000001///regulation of DNA damage checkpoint+++GO:0016567///protein ubiquitination+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0060442///branching involved in prostate gland morphogenesis+++GO:0002070///epithelial cell maturation+++GO:0043687///post-translational protein modification+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0006915///apoptotic process","IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR002110///Ankyrin repeat","[FEM1B_HUMAN|Reviewed]RecName: Full=Protein fem-1 homolog B; Short=FEM1b; AltName: Full=FEM1-beta; AltName: Full=Fem-1-like death receptor-binding protein alpha; AltName: Full=Fem-1-like in apoptotic pathway protein alpha; Short=F1A-alpha;+++[H3BT12_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000456968}; Flags: Fragment;+++[H3BTV3_HUMAN|Unreviewed]SubName: Full=Protein fem-1 homolog B {ECO:0000313|Ensembl:ENSP00000457342}; Flags: Fragment;"]
[1012,"'CDH13'",134,146,140,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0062023///collagen-containing extracellular matrix+++GO:0043005///neuron projection+++GO:0016342///catenin complex+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane+++GO:0005913///cell-cell adherens junction+++GO:0009986///cell surface+++GO:0048471///perinuclear region of cytoplasm+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0098982///GABA-ergic synapse+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0042803///protein homodimerization activity+++GO:0055100///adiponectin binding+++GO:0071813///lipoprotein particle binding+++GO:0008092///cytoskeletal protein binding+++GO:0045296///cadherin binding+++GO:0030169///low-density lipoprotein particle binding","GO:0010033///response to organic substance+++GO:0007266///Rho protein signal transduction+++GO:0050850///positive regulation of calcium-mediated signaling+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0034332///adherens junction organization+++GO:0030335///positive regulation of cell migration+++GO:0043542///endothelial cell migration+++GO:0043616///keratinocyte proliferation+++GO:0016601///Rac protein signal transduction+++GO:0050927///positive regulation of positive chemotaxis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0042058///regulation of epidermal growth factor receptor signaling pathway+++GO:0007043///cell-cell junction assembly+++GO:0030032///lamellipodium assembly+++GO:0030100///regulation of endocytosis+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007162///negative regulation of cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0002040///sprouting angiogenesis+++GO:0007155///cell adhesion+++GO:0000278///mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051668///localization within membrane","IPR039808///Cadherin+++IPR015919///Cadherin-like superfamily+++IPR014868///Cadherin prodomain+++IPR002126///Cadherin-like+++IPR033216///Cadherin-13+++IPR020894///Cadherin conserved site","[CAD13_HUMAN|Reviewed]RecName: Full=Cadherin-13; AltName: Full=Heart cadherin; Short=H-cadherin; AltName: Full=P105; AltName: Full=Truncated cadherin; Short=T-cad; Short=T-cadherin; Flags: Precursor;+++[B7Z3H7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50547, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH12213.1};+++[B7Z9B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52398, highly similar to Cadherin-13 {ECO:0000313|EMBL:BAH14247.1};+++[F5H7W7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000442225};+++[H3BQH4_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000455781};+++[H3BRL7_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000456297};+++[H3BTF2_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457149};+++[H3BV21_HUMAN|Unreviewed]SubName: Full=Cadherin-13 {ECO:0000313|Ensembl:ENSP00000457914};"]
[10120,"'ACTR1B'",691,631,661,{"$nulls":4},"GO:1904813///ficolin-1-rich granule lumen+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0034774///secretory granule lumen+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0005869///dynactin complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0015630///microtubule cytoskeleton+++GO:0005856///cytoskeleton","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","IPR004000///Actin family+++IPR004001///Actin, conserved site+++IPR020902///Actin/actin-like conserved site+++IPR029909///Actin-related protein 1 family","[ACTY_HUMAN|Reviewed]RecName: Full=Beta-centractin; AltName: Full=Actin-related protein 1B; Short=ARP1B;"]
[10121,"'ACTR1A'",4719,3862,4290.5,{"$nulls":4},"GO:0005869///dynactin complex+++GO:0043209///myelin sheath+++GO:0005829///cytosol+++GO:0099738///cell cortex region+++GO:0030137///COPI-coated vesicle+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0002177///manchette+++GO:0015630///microtubule cytoskeleton+++GO:0005814///centriole+++GO:0070062///extracellular exosome+++GO:0005875///microtubule associated complex+++GO:0005815///microtubule organizing center+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0016192///vesicle-mediated transport+++GO:0007283///spermatogenesis+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport","IPR004001///Actin, conserved site+++IPR004000///Actin family+++IPR020902///Actin/actin-like conserved site+++IPR029909///Actin-related protein 1 family","[ACTZ_HUMAN|Reviewed]RecName: Full=Alpha-centractin; Short=Centractin; AltName: Full=ARP1; AltName: Full=Actin-RPV; AltName: Full=Centrosome-associated actin homolog;+++[A0A1B0GVS3_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000490634};+++[R4GMT0_HUMAN|Unreviewed]SubName: Full=Alpha-centractin {ECO:0000313|Ensembl:ENSP00000473334};"]
[10123,"'ARL4C'",3155,3229,3192,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding+++GO:0005525///GTP binding","GO:0032456///endocytic recycling+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","IPR005225///Small GTP-binding protein domain+++IPR006689///Small GTPase superfamily, ARF/SAR type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[ARL4C_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4C; AltName: Full=ADP-ribosylation factor-like protein 7; AltName: Full=ADP-ribosylation factor-like protein LAK;+++[A0A024R4C5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4C, isoform CRA_a {ECO:0000313|EMBL:EAW71074.1};"]
[10124,"'ARL4A'",150.97,181.99,166.48,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport","IPR005225///Small GTP-binding protein domain+++IPR006689///Small GTPase superfamily, ARF/SAR type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[ARL4A_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-like protein 4A;+++[A0A024R9Z2_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like 4A, isoform CRA_a {ECO:0000313|EMBL:EAW93652.1};+++[C9J7Q9_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor-like protein 4A {ECO:0000313|Ensembl:ENSP00000397651}; Flags: Fragment;"]
[10125,"'RASGRP1'",87,153,120,"05200///Pathways in cancer+++04660///T cell receptor signaling pathway+++04611///Platelet activation+++04014///Ras signaling pathway+++04010///MAPK signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0042629///mast cell granule+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0019992///diacylglycerol binding+++GO:0001786///phosphatidylserine binding+++GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005096///GTPase activator activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031210///phosphatidylcholine binding+++GO:0042803///protein homodimerization activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1900744///regulation of p38MAPK cascade+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0007264///small GTPase mediated signal transduction+++GO:1902715///positive regulation of interferon-gamma secretion+++GO:0090630///activation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0032725///positive regulation of granulocyte macrophage colony-stimulating factor production+++GO:0007165///signal transduction+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0001816///cytokine production+++GO:0043303///mast cell degranulation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043406///positive regulation of MAP kinase activity+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0047496///vesicle transport along microtubule+++GO:0043087///regulation of GTPase activity+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0046330///positive regulation of JNK cascade+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0007265///Ras protein signal transduction+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0000165///MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0032252///secretory granule localization+++GO:1900274///regulation of phospholipase C activity+++GO:0030154///cell differentiation+++GO:0032816///positive regulation of natural killer cell activation","IPR001895///Ras guanine-nucleotide exchange factors catalytic domain+++IPR036964///Ras guanine-nucleotide exchange factor catalytic domain superfamily+++IPR023578///Ras guanine nucleotide exchange factor domain superfamily+++IPR002048///EF-hand domain+++IPR020454///Diacylglycerol/phorbol-ester binding+++IPR000651///Ras-like guanine nucleotide exchange factor, N-terminal+++IPR008937///Ras-like guanine nucleotide exchange factor+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR011992///EF-hand domain pair+++IPR018247///EF-Hand 1, calcium-binding site+++IPR029645///Ras guanyl-releasing protein 1/3","[GRP1_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 1; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor II; Short=CalDAG-GEFII; AltName: Full=Ras guanyl-releasing protein;+++[B2RA89_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94771, highly similar to Homo sapiens RAS guanyl releasing protein 1 (calcium and DAG-regulated) (RASGRP1), mRNA {ECO:0000313|EMBL:BAG36786.1};+++[F5H514_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000444762};+++[H0YKM0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452859};+++[H0YKP8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000452892}; Flags: Fragment;+++[H0YMF3_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453583}; Flags: Fragment;+++[H0YMT0_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453729}; Flags: Fragment;+++[H0YN83_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000453905}; Flags: Fragment;+++[H0YNG8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454005}; Flags: Fragment;+++[H0YNK9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 1 {ECO:0000313|Ensembl:ENSP00000454053}; Flags: Fragment;"]
[10126,"'DNAL4'",299,249,274,"05016///Huntington's disease",{"$nulls":3},"GO:0005874///microtubule+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0030286///dynein complex+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005929///cilium","GO:0051959///dynein light intermediate chain binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed+++GO:0005515///protein binding+++GO:0003774///motor activity+++GO:0003777///microtubule motor activity+++GO:0045505///dynein intermediate chain binding","GO:0007018///microtubule-based movement+++GO:2000582///positive regulation of ATP-dependent microtubule motor activity, plus-end-directed+++GO:0007017///microtubule-based process","IPR001372///Dynein light chain, type 1/2+++IPR037177///Dynein light chain superfamily","[DNAL4_HUMAN|Reviewed]RecName: Full=Dynein light chain 4, axonemal;+++[B0QXZ5_HUMAN|Unreviewed]RecName: Full=Dynein light chain {ECO:0000256|RuleBase:RU365010};"]
[10127,"'ZNF263'",299,284,291.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR038269///SCAN domain superfamily+++IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR003309///SCAN domain","[ZN263_HUMAN|Reviewed]RecName: Full=Zinc finger protein 263; AltName: Full=Zinc finger protein FPM315; AltName: Full=Zinc finger protein with KRAB and SCAN domains 12;+++[B4DI05_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57935, highly similar to Zinc finger protein 263 {ECO:0000313|EMBL:BAG58317.1};+++[D3DUC1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263, isoform CRA_a {ECO:0000313|EMBL:EAW85380.1};+++[I3L0N0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000458214}; Flags: Fragment;+++[I3L2X3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000459998};+++[I3L393_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000460278};+++[I3L4C4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461146}; Flags: Fragment;+++[I3L538_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461755}; Flags: Fragment;+++[I3NI39_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 263 {ECO:0000313|Ensembl:ENSP00000461861}; Flags: Fragment;"]
[10128,"'LRPPRC'",883,931,907,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01354///Leigh syndrome+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0000794///condensed nuclear chromosome+++GO:1990904///ribonucleoprotein complex+++GO:0005874///microtubule+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005640///nuclear outer membrane+++GO:0005634///nucleus+++GO:0042645///mitochondrial nucleoid+++GO:0005637///nuclear inner membrane+++GO:0005856///cytoskeleton","GO:0008017///microtubule binding+++GO:0048487///beta-tubulin binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0051015///actin filament binding+++GO:0003697///single-stranded DNA binding","GO:0070129///regulation of mitochondrial translation+++GO:0051028///mRNA transport+++GO:0000961///negative regulation of mitochondrial RNA catabolic process+++GO:0047497///mitochondrion transport along microtubule","IPR033443///Pentacotripeptide-repeat region of PRORP+++IPR002885///Pentatricopeptide repeat+++IPR033490///Leucine-rich PPR motif-containing protein+++IPR011990///Tetratricopeptide-like helical domain superfamily","[LPPRC_HUMAN|Reviewed]RecName: Full=Leucine-rich PPR motif-containing protein, mitochondrial; AltName: Full=130 kDa leucine-rich protein; Short=LRP 130; AltName: Full=GP130; Flags: Precursor;+++[A0A0C4DG06_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386234};+++[B8ZZ38_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000386562};+++[C9JCA9_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000403637}; Flags: Fragment;+++[E5KNY5_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR-motif containing {ECO:0000313|EMBL:EAX00284.1}; SubName: Full=Mitochondrial leucine-rich PPR motif-containing protein {ECO:0000313|EMBL:ADP90894.1};+++[H7C3W8_HUMAN|Unreviewed]SubName: Full=Leucine-rich PPR motif-containing protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000414207}; Flags: Fragment;"]
[10129,"'FRY'",94,153,123.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0004857///enzyme inhibitor activity","GO:0000902///cell morphogenesis+++GO:0043086///negative regulation of catalytic activity+++GO:0031175///neuron projection development+++GO:1904428///negative regulation of tubulin deacetylation","IPR025481///Cell morphogenesis protein C-terminal+++IPR025614///Cell morphogenesis protein N-terminal+++IPR016024///Armadillo-type fold+++IPR029473///Cell morphogenesis central region+++IPR039867///Protein furry/Tao3/Mor2","[FRY_HUMAN|Reviewed]RecName: Full=Protein furry homolog;+++[A0A024RDQ1_HUMAN|Unreviewed]SubName: Full=Furry homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAX08493.1};+++[A0A0C4DFX2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000369600};+++[A0A286YFA9_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000493189};+++[A0A2R8Y5V8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494761};+++[A0A2R8Y7Y8_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000496501}; Flags: Fragment;+++[A0A2R8YCY2_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000494080};+++[B1ALA1_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000398010}; Flags: Fragment;+++[H0YE00_HUMAN|Unreviewed]SubName: Full=Protein furry homolog {ECO:0000313|Ensembl:ENSP00000434694}; Flags: Fragment;+++[L8EB55_HUMAN|Unreviewed]SubName: Full=Alternative protein FRY {ECO:0000313|EMBL:CCQ43703.1};+++[Q96KW3_HUMAN|Unreviewed]SubName: Full=214K23.2.1 (Novel protein, isoform 1) {ECO:0000313|EMBL:CAC94765.1}; Flags: Fragment;+++[Q96KW4_HUMAN|Unreviewed]SubName: Full=214K23.2.2 (Novel protein, isoform 2) {ECO:0000313|EMBL:CAC94764.1}; Flags: Fragment;"]
[1013,"'CDH15'",6,4,5,"04514///Cell adhesion molecules (CAMs)","H00773///Autosomal dominant mental retardation",null,null,"GO:0005901///caveola+++GO:0031594///neuromuscular junction+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005913///cell-cell adherens junction+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0016342///catenin complex","GO:0008092///cytoskeletal protein binding+++GO:0046872///metal ion binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0003674///molecular_function+++GO:0042803///protein homodimerization activity","GO:0042060///wound healing+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:1902910///positive regulation of melanosome transport+++GO:0050896///response to stimulus+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0022405///hair cycle process+++GO:0032912///negative regulation of transforming growth factor beta2 production+++GO:0042493///response to drug+++GO:0007155///cell adhesion+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0007601///visual perception+++GO:0031424///keratinization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051796///negative regulation of timing of catagen+++GO:0032773///positive regulation of monophenol monooxygenase activity+++GO:0007043///cell-cell junction assembly+++GO:0001895///retina homeostasis+++GO:0060901///regulation of hair cycle by canonical Wnt signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0010838///positive regulation of keratinocyte proliferation","IPR002126///Cadherin-like+++IPR039808///Cadherin+++IPR027397///Catenin binding domain superfamily+++IPR020894///Cadherin conserved site+++IPR015919///Cadherin-like superfamily+++IPR000233///Cadherin, cytoplasmic domain","[CAD15_HUMAN|Reviewed]RecName: Full=Cadherin-15; AltName: Full=Cadherin-14; AltName: Full=Muscle cadherin; Short=M-cadherin; Flags: Precursor;+++[J3KRQ1_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000462111}; Flags: Fragment;+++[J3QKW6_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463267}; Flags: Fragment;+++[J3QL41_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463364}; Flags: Fragment;+++[J3QL75_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000463415}; Flags: Fragment;+++[J3QR34_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464021};+++[J3QR60_HUMAN|Unreviewed]SubName: Full=Cadherin-3 {ECO:0000313|Ensembl:ENSP00000464058}; Flags: Fragment;"]
[10130,"'PDIA6'",4888,4983,4935.5,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0042470///melanosome+++GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005783///endoplasmic reticulum+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0003756///protein disulfide isomerase activity+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0006457///protein folding+++GO:0044267///cellular protein metabolic process+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process","IPR013766///Thioredoxin domain+++IPR005788///Disulphide isomerase+++IPR017937///Thioredoxin, conserved site+++IPR036249///Thioredoxin-like superfamily","[PDIA6_HUMAN|Reviewed]RecName: Full=Protein disulfide-isomerase A6; EC=5.3.4.1 {ECO:0000269|PubMed:12204115, ECO:0000269|PubMed:15466936}; AltName: Full=Endoplasmic reticulum protein 5; Short=ER protein 5; Short=ERp5; AltName: Full=Protein disulfide isomerase P5; AltName: Full=Thioredoxin domain-containing protein 7; Flags: Precursor;+++[C9JNG5_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A6 {ECO:0000313|Ensembl:ENSP00000389558}; Flags: Fragment;"]
[10131,"'TRAP1'",1227,1037,1132,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005758///mitochondrial intermembrane space+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005759///mitochondrial matrix","GO:0051082///unfolded protein binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003723///RNA binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0061077///chaperone-mediated protein folding+++GO:0009386///translational attenuation+++GO:1901856///negative regulation of cellular respiration+++GO:0006950///response to stress+++GO:1903751///negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:1903427///negative regulation of reactive oxygen species biosynthetic process","IPR037196///HSP90, C-terminal domain+++IPR036890///Histidine kinase/HSP90-like ATPase superfamily+++IPR020568///Ribosomal protein S5 domain 2-type fold+++IPR001404///Heat shock protein Hsp90 family+++IPR020575///Heat shock protein Hsp90, N-terminal+++IPR003594///Histidine kinase/HSP90-like ATPase","[TRAP1_HUMAN|Reviewed]RecName: Full=Heat shock protein 75 kDa, mitochondrial; Short=HSP 75; AltName: Full=TNFR-associated protein 1; AltName: Full=Tumor necrosis factor type 1 receptor-associated protein; Short=TRAP-1; Flags: Precursor;+++[A0A140VJY2_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 209 {ECO:0000313|EMBL:AEE61119.1};+++[I3L0K7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458166}; SubName: Full=TNF receptor-associated protein 1, isoform CRA_b {ECO:0000313|EMBL:EAW85339.1};+++[I3L0P6_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000458244}; Flags: Fragment;+++[I3L239_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459354}; Flags: Fragment;+++[I3L253_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459385}; Flags: Fragment;+++[I3L2D5_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000459585}; Flags: Fragment;+++[I3L3L4_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000460545};+++[I3L4L7_HUMAN|Unreviewed]SubName: Full=Heat shock protein 75 kDa, mitochondrial {ECO:0000313|Ensembl:ENSP00000461354};+++[K0A7K7_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:AFS69159.1}; Flags: Fragment;+++[Q53FS6_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 variant {ECO:0000313|EMBL:BAD96925.1}; Flags: Fragment;+++[Q5CAQ4_HUMAN|Unreviewed]SubName: Full=TNF receptor-associated protein 1 {ECO:0000313|EMBL:CAI64498.1}; SubName: Full=cDNA FLJ33058 fis, clone TRACH1000181, highly similar to Heat shock protein 75 kDa, mitochondrial {ECO:0000313|EMBL:BAG51942.1};+++[Q9BV61_HUMAN|Unreviewed]SubName: Full=TRAP1 protein {ECO:0000313|EMBL:AAH01455.2}; Flags: Fragment;"]
[10133,"'OPTN'",2090,1681,1885.5,"04137///Mitophagy - animal","H00612///Primary open angle glaucoma+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0055037///recycling endosome+++GO:0005802///trans-Golgi network+++GO:0005776///autophagosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005768///endosome+++GO:0005634///nucleus","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0030674///protein binding, bridging+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding","GO:0045087///innate immune response+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016192///vesicle-mediated transport+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007030///Golgi organization+++GO:0090161///Golgi ribbon formation+++GO:1904417///positive regulation of xenophagy+++GO:0006914///autophagy+++GO:0001920///negative regulation of receptor recycling+++GO:0008219///cell death+++GO:0034067///protein localization to Golgi apparatus+++GO:0034620///cellular response to unfolded protein+++GO:0002376///immune system process+++GO:0050829///defense response to Gram-negative bacterium+++GO:0034613///cellular protein localization+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0010508///positive regulation of autophagy+++GO:0007165///signal transduction","IPR032939///Optineurin+++IPR032419///NF-kappa-B essential modulator NEMO, CC2-LZ domain+++IPR021063///NF-kappa-B essential modulator NEMO, N-terminal+++IPR034735///NEMO, Zinc finger","[OPTN_HUMAN|Reviewed]RecName: Full=Optineurin; AltName: Full=E3-14.7K-interacting protein; AltName: Full=FIP-2; AltName: Full=Huntingtin yeast partner L; AltName: Full=Huntingtin-interacting protein 7; Short=HIP-7; AltName: Full=Huntingtin-interacting protein L; AltName: Full=NEMO-related protein; AltName: Full=Optic neuropathy-inducing protein; AltName: Full=Transcription factor IIIA-interacting protein; Short=TFIIIA-IntP;+++[A0A087WY28_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000481473}; Flags: Fragment;+++[A0A087X2G2_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000484961};+++[A0A0S2Z500_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 1 {ECO:0000313|EMBL:ALQ33960.1}; Flags: Fragment;+++[A0A0S2Z5I6_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 3 {ECO:0000313|EMBL:ALQ33961.1};+++[H7C1H4_HUMAN|Unreviewed]SubName: Full=Optineurin {ECO:0000313|Ensembl:ENSP00000400356}; Flags: Fragment;+++[X6RKL2_HUMAN|Unreviewed]SubName: Full=Optineurin isoform 4 {ECO:0000313|EMBL:ALQ33962.1};"]
[10134,"'BCAP31'",3637,3198,3417.5,"05165///Human papillomavirus infection+++04141///Protein processing in endoplasmic reticulum","H00849///Creatine deficiency syndrome+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0030136///clathrin-coated vesicle+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005739///mitochondrion+++GO:0032580///Golgi cisterna membrane+++GO:0071556///integral component of lumenal side of endoplasmic reticulum membrane+++GO:0005784///Sec61 translocon complex+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005811///lipid droplet+++GO:0005887///integral component of plasma membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0042288///MHC class I protein binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0015031///protein transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007283///spermatogenesis+++GO:0032471///negative regulation of endoplasmic reticulum calcium ion concentration+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0006886///intracellular protein transport+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:1903071///positive regulation of ER-associated ubiquitin-dependent protein catabolic process+++GO:0016192///vesicle-mediated transport+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0006915///apoptotic process","IPR008417///B-cell receptor-associated protein 29/31","[BAP31_HUMAN|Reviewed]RecName: Full=B-cell receptor-associated protein 31; Short=BCR-associated protein 31; Short=Bap31; AltName: Full=6C6-AG tumor-associated antigen; AltName: Full=Protein CDM; AltName: Full=p28;+++[A0A2R8Y5M6_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000494936};+++[C9J0M4_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000400345}; Flags: Fragment;+++[C9JM14_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000402342}; Flags: Fragment;+++[C9JMD7_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000389740}; Flags: Fragment;+++[C9JQ75_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000409888}; Flags: Fragment;+++[C9JSP1_HUMAN|Unreviewed]SubName: Full=B-cell receptor-associated protein 31 {ECO:0000313|Ensembl:ENSP00000394270}; Flags: Fragment;"]
[10135,"'NAMPT'",438,423,430.5,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways+++04621///NOD-like receptor signaling pathway",null,null,"R01271///nicotinamide-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase   Nicotinamide D-ribonucleotide + Diphosphate <=> Nicotinamide + 5-Phospho-alpha-D-ribose 1-diphosphate","GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0030054///cell junction+++GO:0005615///extracellular space","GO:0042803///protein homodimerization activity+++GO:0008144///drug binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0047280///nicotinamide phosphoribosyltransferase activity+++GO:0042802///identical protein binding+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0005125///cytokine activity","GO:0014070///response to organic cyclic compound+++GO:0009435///NAD biosynthetic process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0060612///adipose tissue development+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0001774///microglial cell activation+++GO:0008284///positive regulation of cell proliferation+++GO:1905377///response to D-galactose+++GO:0070997///neuron death+++GO:0032922///circadian regulation of gene expression+++GO:0007568///aging+++GO:0010469///regulation of signaling receptor activity+++GO:1904646///cellular response to amyloid-beta+++GO:0007565///female pregnancy+++GO:0090650///cellular response to oxygen-glucose deprivation+++GO:0010507///negative regulation of autophagy+++GO:0007267///cell-cell signaling+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0007623///circadian rhythm+++GO:0048511///rhythmic process+++GO:0034356///NAD biosynthesis via nicotinamide riboside salvage pathway+++GO:0014916///regulation of lung blood pressure","IPR016471///Nicotinamide phosphoribosyl transferase+++IPR013785///Aldolase-type TIM barrel+++IPR007229///Nicotinate phosphoribosyltransferase family+++IPR036068///Nicotinate phosphoribosyltransferase-like, C-terminal","[NAMPT_HUMAN|Reviewed]RecName: Full=Nicotinamide phosphoribosyltransferase; Short=NAmPRTase; Short=Nampt; EC=2.4.2.12; AltName: Full=Pre-B-cell colony-enhancing factor 1; Short=Pre-B cell-enhancing factor; AltName: Full=Visfatin;+++[A0A024R718_HUMAN|Unreviewed]SubName: Full=Pre-B-cell colony enhancing factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW83384.1};+++[A0A0C4DFS8_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000346242};+++[C9JF35_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390896}; Flags: Fragment;+++[C9JG65_HUMAN|Unreviewed]SubName: Full=Nicotinamide phosphoribosyltransferase {ECO:0000313|Ensembl:ENSP00000390591}; Flags: Fragment;"]
[10137,"'RBM12'",652,796,724,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding",null,"IPR034594///RBM12, RNA recognition motif 2+++IPR034856///RBM12, RNA recognition motif 4+++IPR034855///RBM12, RNA recognition motif 3+++IPR035979///RNA-binding domain superfamily+++IPR034591///RBM12, RNA recognition motif 1+++IPR000504///RNA recognition motif domain+++IPR034854///RBM12, RNA recognition motif 5+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[RBM12_HUMAN|Reviewed]RecName: Full=RNA-binding protein 12; AltName: Full=RNA-binding motif protein 12; AltName: Full=SH3/WW domain anchor protein in the nucleus; Short=SWAN;+++[A6PVI0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000392642}; Flags: Fragment;+++[A6PVI1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411692}; Flags: Fragment;+++[Q5JX62_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 12 {ECO:0000313|Ensembl:ENSP00000411036}; Flags: Fragment;"]
[10138,"'YAF2'",167,206,186.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0003714///transcription corepressor activity","GO:0070317///negative regulation of G0 to G1 transition+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated","IPR036443///Zinc finger, RanBP2-type superfamily+++IPR038039///YY1-associated factor 2+++IPR039958///RING1 and YY1-binding protein/YY1-associated factor 2+++IPR001876///Zinc finger, RanBP2-type+++IPR033774///Yaf2/RYBP C-terminal binding motif","[YAF2_HUMAN|Reviewed]RecName: Full=YY1-associated factor 2;+++[A0A0B4J255_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447863};+++[B4DJQ9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57510, highly similar to YY1-associated factor 2 {ECO:0000313|EMBL:BAG58921.1};+++[F8VRE5_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448533};+++[F8VZR2_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447686}; Flags: Fragment;+++[F8W0B9_HUMAN|Unreviewed]SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000447217};+++[G3V1X5_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_g {ECO:0000313|EMBL:EAW57840.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000448291};+++[G3V212_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_b {ECO:0000313|EMBL:EAW57835.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450097};+++[G3V219_HUMAN|Unreviewed]SubName: Full=YY1 associated factor 2, isoform CRA_d {ECO:0000313|EMBL:EAW57837.1}; SubName: Full=YY1-associated factor 2 {ECO:0000313|Ensembl:ENSP00000450394};"]
[10139,"'ARFRP1'",444,391,417.5,"04060///Cytokine-cytokine receptor interaction","H00108///Autoimmune lymphoproliferative syndromes (ALPS)",null,null,"GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0032588///trans-Golgi network membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:0007369///gastrulation+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0007165///signal transduction+++GO:0033365///protein localization to organelle+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0034067///protein localization to Golgi apparatus+++GO:0006886///intracellular protein transport","IPR005225///Small GTP-binding protein domain+++IPR006689///Small GTPase superfamily, ARF/SAR type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[ARFRP_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor-related protein 1; Short=ARF-related protein 1; Short=ARP;+++[B7ZKY8_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1 {ECO:0000313|EMBL:AAI43468.1};+++[H0UI96_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor related protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW75236.1};"]
[10140,"'TOB1'",781,908,844.5,"03018///RNA degradation",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030014///CCR4-NOT complex","GO:0005515///protein binding+++GO:0046332///SMAD binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0003714///transcription corepressor activity+++GO:0030971///receptor tyrosine kinase binding","GO:0060212///negative regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:0009967///positive regulation of signal transduction+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0017148///negative regulation of translation+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0008285///negative regulation of cell proliferation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060390///regulation of SMAD protein signal transduction+++GO:0010468///regulation of gene expression+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening","IPR015677///Tob1+++IPR036054///BTG-like domain superfamily+++IPR002087///Anti-proliferative protein+++IPR015676///Tob1/2","[TOB1_HUMAN|Reviewed]RecName: Full=Protein Tob1; AltName: Full=Transducer of erbB-2 1;"]
[101410538,"'MMP24OS'",4927,5692,5309.5,{"$nulls":8},"[MMPOS_HUMAN|Reviewed]RecName: Full=Protein MMP24OS {ECO:0000305}; AltName: Full=MMP24 opposite strand {ECO:0000312|HGNC:HGNC:44421};"]
[10142,"'AKAP9'",781.88,812,796.94,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00720///Long QT syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0099147///extrinsic component of postsynaptic density membrane+++GO:0043025///neuronal cell body+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0044307///dendritic branch+++GO:0005795///Golgi stack+++GO:0097060///synaptic membrane+++GO:0005815///microtubule organizing center+++GO:0005801///cis-Golgi network+++GO:0008076///voltage-gated potassium channel complex+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0005813///centrosome","GO:0015459///potassium channel regulator activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0016301///kinase activity+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0034237///protein kinase A regulatory subunit binding","GO:0051602///response to electrical stimulus+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0007165///signal transduction+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0016310///phosphorylation+++GO:1903358///regulation of Golgi organization+++GO:0071320///cellular response to cAMP+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0060306///regulation of membrane repolarization+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity+++GO:0007268///chemical synaptic transmission+++GO:0098962///regulation of postsynaptic neurotransmitter receptor activity+++GO:0051661///maintenance of centrosome location+++GO:0031116///positive regulation of microtubule polymerization+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007020///microtubule nucleation+++GO:0098909///regulation of cardiac muscle cell action potential involved in regulation of contraction+++GO:0000086///G2/M transition of mitotic cell cycle","IPR005539///ELK domain+++IPR019528///Pericentrin/AKAP-450 centrosomal targeting domain+++IPR028745///A-kinase anchor protein 9/Pericentrin","[AKAP9_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 9; Short=AKAP-9; AltName: Full=A-kinase anchor protein 350 kDa; Short=AKAP 350; Short=hgAKAP 350; AltName: Full=A-kinase anchor protein 450 kDa; Short=AKAP 450; AltName: Full=AKAP 120-like protein; AltName: Full=Centrosome- and Golgi-localized PKN-associated protein {ECO:0000303|PubMed:10358086}; Short=CG-NAP {ECO:0000303|PubMed:10358086}; AltName: Full=Protein hyperion {ECO:0000303|Ref.4}; AltName: Full=Protein kinase A-anchoring protein 9; Short=PRKA9; AltName: Full=Protein yotiao {ECO:0000303|PubMed:9482789};+++[A0A087WX84_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000480807};+++[A0A0A0MRE9_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000350813};+++[A0A0A0MRF6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000351922};+++[A0A2R8Y590_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000494626}; Flags: Fragment;+++[A4D1E4_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9 {ECO:0000313|EMBL:EAL24158.1};+++[H0Y6Q0_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000406937}; Flags: Fragment;+++[H7BYL6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378042}; Flags: Fragment;+++[H7BZV6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000391704}; Flags: Fragment;+++[Q5GIA7_HUMAN|Unreviewed]SubName: Full=Antigen MU-RMS-40.16A {ECO:0000313|EMBL:AAT44400.1}; Flags: Fragment;+++[Q6PJH3_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein (Yotiao) 9, isoform CRA_c {ECO:0000313|EMBL:EAW76862.1}; SubName: Full=A-kinase anchor protein 9 {ECO:0000313|Ensembl:ENSP00000378065}; SubName: Full=AKAP9 protein {ECO:0000313|EMBL:AAH15533.1};"]
[10144,"'FAM13A'",106,120,113,"04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","IPR000198///Rho GTPase-activating protein domain+++IPR039102///Protein FAM13+++IPR008936///Rho GTPase activation protein","[FA13A_HUMAN|Reviewed]RecName: Full=Protein FAM13A;+++[A0A2X0SFT1_HUMAN|Unreviewed]SubName: Full=FAM13A {ECO:0000313|EMBL:SPT35754.1}; Flags: Fragment;+++[D6RCC1_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000423800};+++[D6RD35_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000427077};+++[D6RFM4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000426517};+++[D6RGE4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421269}; Flags: Fragment;+++[D6RIY4_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000425784};+++[E9PGM7_HUMAN|Unreviewed]SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000421914};+++[L0R4X6_HUMAN|Unreviewed]SubName: Full=Alternative protein FAM13A {ECO:0000313|EMBL:CCO13728.1};+++[Q6P521_HUMAN|Unreviewed]SubName: Full=FAM13A protein {ECO:0000313|EMBL:AAH63126.1}; SubName: Full=Protein FAM13A {ECO:0000313|Ensembl:ENSP00000422345};"]
[10146,"'G3BP1'",964,1021,992.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0043204///perikaryon+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0010494///cytoplasmic stress granule","GO:0004518///nuclease activity+++GO:0003676///nucleic acid binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0004519///endonuclease activity+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0003729///mRNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005515///protein binding","GO:0034063///stress granule assembly+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0032508///DNA duplex unwinding+++GO:0007265///Ras protein signal transduction","IPR018222///Nuclear transport factor 2, eukaryote+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain+++IPR035979///RNA-binding domain superfamily+++IPR034375///Ras GTPase-activating protein-binding protein 1+++IPR002075///Nuclear transport factor 2+++IPR034374///G3BP1, RNA recognition motif+++IPR032710///NTF2-like domain superfamily+++IPR039539///Ras GTPase-activating protein-binding protein","[G3BP1_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 1; Short=G3BP-1; EC=3.6.4.12 {ECO:0000269|PubMed:9889278}; EC=3.6.4.13 {ECO:0000269|PubMed:9889278}; AltName: Full=ATP-dependent DNA helicase VIII; Short=hDH VIII; AltName: Full=GAP SH3 domain-binding protein 1;+++[E5RH00_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430045};+++[E5RH42_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429920}; Flags: Fragment;+++[E5RI46_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000428469}; Flags: Fragment;+++[E5RIF8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430738}; Flags: Fragment;+++[E5RIZ6_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000429250}; Flags: Fragment;+++[E5RJU8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430480};+++[Q32P45_HUMAN|Unreviewed]SubName: Full=GTPase activating protein (SH3 domain) binding protein 1 {ECO:0000313|EMBL:AAI08279.1};+++[Q5U0Q1_HUMAN|Unreviewed]SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein {ECO:0000313|EMBL:AAV38191.1}; SubName: Full=Ras-GTPase-activating protein SH3-domain-binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW61659.1}; SubName: Full=cDNA, FLJ92947, Homo sapiens Ras-GTPase-activating protein SH3-domain-bindingprotein (G3BP), mRNA {ECO:0000313|EMBL:BAG35467.1};+++[Q6FI03_HUMAN|Unreviewed]SubName: Full=G3BP protein {ECO:0000313|EMBL:CAG38772.1};+++[Q6ZP53_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1 {ECO:0000313|EMBL:BAC85272.1};"]
[10147,"'SUGP2'",1276.8,1438.83,1357.815,{"$nulls":4},"GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0006396///RNA processing+++GO:0008380///RNA splicing","IPR000467///G-patch domain+++IPR000061///SWAP/Surp+++IPR035967///SWAP/Surp superfamily","[SUGP2_HUMAN|Reviewed]RecName: Full=SURP and G-patch domain-containing protein 2; AltName: Full=Arginine/serine-rich-splicing factor 14; AltName: Full=Splicing factor, arginine/serine-rich 14;+++[A0A024R7K0_HUMAN|Unreviewed]SubName: Full=Splicing factor, arginine/serine-rich 14, isoform CRA_a {ECO:0000313|EMBL:EAW84768.1};+++[A8K5G0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76836, highly similar to Homo sapiens splicing factor, arginine/serine-rich 14 (SFRS14), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83964.1};+++[M0R065_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000471042}; Flags: Fragment;+++[M0R1Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472183}; Flags: Fragment;+++[M0R216_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472244}; Flags: Fragment;+++[M0R2Y3_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472878}; Flags: Fragment;+++[M0R2Z9_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000472914};+++[M0R3F6_HUMAN|Unreviewed]SubName: Full=SURP and G-patch domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000473187};"]
[10148,"'EBI3'",34,20,27,{"$nulls":4},"GO:0070110///ciliary neurotrophic factor receptor complex+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0043235///receptor complex+++GO:0097059///CNTFR-CLCF1 complex","GO:0004897///ciliary neurotrophic factor receptor activity+++GO:0004896///cytokine receptor activity+++GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0045523///interleukin-27 receptor binding+++GO:0019955///cytokine binding","GO:0006959///humoral immune response+++GO:0042088///T-helper 1 type immune response+++GO:0046641///positive regulation of alpha-beta T cell proliferation+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0070757///interleukin-35-mediated signaling pathway+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0070120///ciliary neurotrophic factor-mediated signaling pathway+++GO:0010469///regulation of signaling receptor activity+++GO:0042098///T cell proliferation","IPR003530///Long hematopoietin receptor, soluble alpha chain, conserved site+++IPR013783///Immunoglobulin-like fold+++IPR003961///Fibronectin type III+++IPR036116///Fibronectin type III superfamily","[IL27B_HUMAN|Reviewed]RecName: Full=Interleukin-27 subunit beta; Short=IL-27 subunit beta; Short=IL-27B; AltName: Full=Epstein-Barr virus-induced gene 3 protein; Short=EBV-induced gene 3 protein; Flags: Precursor;"]
[10149,"'ADGRG2'",1,0,0.5,null,"H01033///Congenital bilateral absence of vas deferens",null,null,"GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome","GO:0004930///G protein-coupled receptor activity+++GO:0004888///transmembrane signaling receptor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007283///spermatogenesis+++GO:0007166///cell surface receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","IPR017981///GPCR, family 2-like+++IPR000832///GPCR, family 2, secretin-like+++IPR000203///GPS motif+++IPR017983///GPCR, family 2, secretin-like, conserved site","[AGRG2_HUMAN|Reviewed]RecName: Full=Adhesion G-protein coupled receptor G2 {ECO:0000303|PubMed:25713288}; AltName: Full=G-protein coupled receptor 64; AltName: Full=Human epididymis-specific protein 6; Short=He6; Flags: Precursor;+++[A0A024RC03_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64, isoform CRA_a {ECO:0000313|EMBL:EAW98954.1};+++[A8K4P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77493, highly similar to Homo sapiens G protein-coupled receptor 64 (GPR64), mRNA {ECO:0000313|EMBL:BAF83701.1};+++[Q14CE1_HUMAN|Unreviewed]SubName: Full=GPR64 protein {ECO:0000313|EMBL:AAI13979.1};+++[Q499H0_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 64 {ECO:0000313|EMBL:AAH99901.1};"]
[10150,"'MBNL2'",1465,1956,1710.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0003723///RNA binding","GO:0008380///RNA splicing+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","IPR000571///Zinc finger, CCCH-type","[MBNL2_HUMAN|Reviewed]RecName: Full=Muscleblind-like protein 2; AltName: Full=Muscleblind-like protein 1; AltName: Full=Muscleblind-like protein-like; AltName: Full=Muscleblind-like protein-like 39;+++[A0PJJ3_HUMAN|Unreviewed]SubName: Full=MBNL2 protein {ECO:0000313|EMBL:AAH32426.1}; Flags: Fragment;+++[A2A3S3_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAX08968.1}; SubName: Full=cDNA FLJ76890, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF84416.1}; SubName: Full=cDNA, FLJ79493, highly similar to Homo sapiens muscleblind-like 2 (Drosophila) (MBNL2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF98735.1};+++[O95205_HUMAN|Unreviewed]SubName: Full=Muscleblind-like 2 (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAX08969.1}; SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000432422}; SubName: Full=Zinc finger protein {ECO:0000313|EMBL:AAC67242.1};+++[Q5JSC0_HUMAN|Unreviewed]SubName: Full=Muscleblind-like protein 2 {ECO:0000313|Ensembl:ENSP00000404202}; Flags: Fragment;"]
[10152,"'ABI2'",560.03,707.18,633.605,"04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0030027///lamellipodium+++GO:0032433///filopodium tip+++GO:0030054///cell junction+++GO:0031209///SCAR complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030175///filopodium+++GO:0005634///nucleus+++GO:0005912///adherens junction","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0017124///SH3 domain binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0048365///Rac GTPase binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0003674///molecular_function+++GO:0070064///proline-rich region binding","GO:0016032///viral process+++GO:0007399///nervous system development+++GO:0016477///cell migration+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation+++GO:0008150///biological_process+++GO:0008154///actin polymerization or depolymerization+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0016601///Rac protein signal transduction+++GO:0007010///cytoskeleton organization","IPR035726///Abl interactor 2, SH3 domain+++IPR000727///Target SNARE coiled-coil homology domain+++IPR012849///Abl-interactor, homeo-domain homologous domain+++IPR001452///SH3 domain+++IPR036028///SH3-like domain superfamily+++IPR028456///Abl interactor 1+++IPR028457///ABI family+++IPR036993///ABL interactor 2","[ABI2_HUMAN|Reviewed]RecName: Full=Abl interactor 2 {ECO:0000303|Ref.16}; AltName: Full=Abelson interactor 2 {ECO:0000303|Ref.16}; Short=Abi-2 {ECO:0000303|PubMed:7590236}; AltName: Full=Abl-binding protein 3; Short=AblBP3; AltName: Full=Arg-binding protein 1 {ECO:0000303|PubMed:8649853}; Short=ArgBP1 {ECO:0000303|PubMed:8649853};+++[A0A0C4DG21_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000391433};+++[B7Z836_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51162, highly similar to Abl interactor 2 {ECO:0000313|EMBL:BAH13822.1};+++[E7EP65_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000414703}; Flags: Fragment;+++[E7EUA1_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000398487};+++[E7EW77_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000396249};+++[E9PEZ7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408898};+++[F8WAL6_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000261018};+++[F8WAQ3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000410509}; Flags: Fragment;+++[F8WAU3_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405255};+++[F8WAZ8_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000397850};+++[F8WBL5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000405801};+++[F8WCD7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000399040};+++[F8WEB9_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000408334};+++[H0Y6B5_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000404352}; Flags: Fragment;+++[H7C3Q7_HUMAN|Unreviewed]SubName: Full=Abl interactor 2 {ECO:0000313|Ensembl:ENSP00000413375}; Flags: Fragment;+++[Q13802_HUMAN|Unreviewed]SubName: Full=ArgBPIB protein {ECO:0000313|EMBL:CAA64980.1};+++[Q53RS4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14935.1}; Flags: Fragment;+++[Q53SH3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ABI-2 {ECO:0000313|EMBL:AAY14675.1}; Flags: Fragment;"]
[10153,"'CEBPZ'",213,283,248,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031966///mitochondrial membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","IPR005612///CCAAT-binding factor+++IPR016024///Armadillo-type fold","[CEBPZ_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein zeta; AltName: Full=CCAAT-box-binding transcription factor; Short=CBF; Short=CCAAT-binding factor;+++[C9J9W7_HUMAN|Unreviewed]SubName: Full=CCAAT/enhancer-binding protein zeta {ECO:0000313|Ensembl:ENSP00000391881}; Flags: Fragment;"]
[10154,"'PLXNC1'",4,2,3,"04360///Axon guidance","H00537///Nephronophthisis",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0002116///semaphorin receptor complex","GO:0017154///semaphorin receptor activity+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0007162///negative regulation of cell adhesion+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:0008360///regulation of cell shape+++GO:0030334///regulation of cell migration+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007165///signal transduction+++GO:0050772///positive regulation of axonogenesis+++GO:0043087///regulation of GTPase activity+++GO:0007155///cell adhesion","IPR016201///PSI domain+++IPR013548///Plexin, cytoplasmic RasGAP domain+++IPR001627///Sema domain+++IPR036352///Sema domain superfamily+++IPR002909///IPT domain+++IPR002165///Plexin repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR008936///Rho GTPase activation protein+++IPR013783///Immunoglobulin-like fold+++IPR031148///Plexin family","[PLXC1_HUMAN|Reviewed]RecName: Full=Plexin-C1; AltName: Full=Virus-encoded semaphorin protein receptor; AltName: CD_antigen=CD232; Flags: Precursor;+++[B4DHQ7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60256, highly similar to Plexin-C1 {ECO:0000313|EMBL:BAG58219.1};+++[F5H3A2_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000439225};+++[F8VUW4_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447843}; Flags: Fragment;+++[F8W095_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000447625}; Flags: Fragment;+++[F8W1K6_HUMAN|Unreviewed]SubName: Full=Plexin-C1 {ECO:0000313|Ensembl:ENSP00000446781};"]
[10155,"'TRIM28'",5284,4665,4974.5,{"$nulls":4},"GO:0005720///nuclear heterochromatin+++GO:0000785///chromatin+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005719///nuclear euchromatin","GO:0043565///sequence-specific DNA binding+++GO:0035851///Krueppel-associated box domain binding+++GO:1990841///promoter-specific chromatin binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0070087///chromo shadow domain binding+++GO:0003714///transcription corepressor activity+++GO:0019789///SUMO transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0007566///embryo implantation+++GO:0016567///protein ubiquitination+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0060669///embryonic placenta morphogenesis+++GO:1901536///negative regulation of DNA demethylation+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0060028///convergent extension involved in axis elongation+++GO:0006281///DNA repair+++GO:0007265///Ras protein signal transduction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0001701///in utero embryonic development+++GO:0001837///epithelial to mesenchymal transition+++GO:0051259///protein complex oligomerization+++GO:1902187///negative regulation of viral release from host cell+++GO:0045087///innate immune response+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:2000653///regulation of genetic imprinting+++GO:0042307///positive regulation of protein import into nucleus+++GO:0006325///chromatin organization+++GO:0016925///protein sumoylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045739///positive regulation of DNA repair+++GO:0006468///protein phosphorylation+++GO:0043045///DNA methylation involved in embryo development+++GO:0016032///viral process+++GO:0043388///positive regulation of DNA binding","IPR000315///B-box-type zinc finger+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR037373///Transcription intermediary factor 1-beta+++IPR003649///B-box, C-terminal+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001487///Bromodomain+++IPR036427///Bromodomain-like superfamily+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR019787///Zinc finger, PHD-finger+++IPR001965///Zinc finger, PHD-type","[TIF1B_HUMAN|Reviewed]RecName: Full=Transcription intermediary factor 1-beta; Short=TIF1-beta; AltName: Full=E3 SUMO-protein ligase TRIM28; EC=2.3.2.27; AltName: Full=KRAB-associated protein 1; Short=KAP-1; AltName: Full=KRAB-interacting protein 1; Short=KRIP-1; AltName: Full=Nuclear corepressor KAP-1; AltName: Full=RING finger protein 96; AltName: Full=RING-type E3 ubiquitin transferase TIF1-beta {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 28;+++[M0QZE6_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000470503}; Flags: Fragment;+++[M0R0K9_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000471303}; Flags: Fragment;+++[M0R2I3_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000472586}; Flags: Fragment;+++[M0R3C0_HUMAN|Unreviewed]SubName: Full=Transcription intermediary factor 1-beta {ECO:0000313|Ensembl:ENSP00000473126}; Flags: Fragment;"]
[10156,"'RASA4'",322.27,364.59,343.43,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding+++GO:0005543///phospholipid binding","GO:0071277///cellular response to calcium ion+++GO:0035556///intracellular signal transduction+++GO:0000165///MAPK cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0034260///negative regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0007165///signal transduction","IPR000008///C2 domain+++IPR001562///Zinc finger, Btk motif+++IPR037777///RASA4, PH domain+++IPR039360///Ras GTPase-activating protein+++IPR035892///C2 domain superfamily+++IPR011993///PH-like domain superfamily+++IPR008936///Rho GTPase activation protein+++IPR023152///Ras GTPase-activating protein, conserved site+++IPR001849///Pleckstrin homology domain+++IPR001936///Ras GTPase-activating domain","[RASL2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 4; AltName: Full=Calcium-promoted Ras inactivator; AltName: Full=Ras p21 protein activator 4; AltName: Full=RasGAP-activating-like protein 2;+++[A0A087WUJ9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000478719};+++[B7ZL55_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI43585.1};+++[E5RGQ8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428732}; Flags: Fragment;+++[E5RID2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428448}; Flags: Fragment;+++[E5RK78_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430418}; Flags: Fragment;+++[E7ERK1_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000417395};+++[H0YB35_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000428605}; Flags: Fragment;+++[H0YBU2_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein 4 {ECO:0000313|Ensembl:ENSP00000430337}; Flags: Fragment;+++[Q2NL74_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 4 {ECO:0000313|EMBL:AAI10874.1};"]
[10157,"'AASS'",107.48,144.12,125.8,"01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++00310///Lysine degradation+++01100///Metabolic pathways","H01242///Saccharopinuria+++H00188///Hyperlysinemia","M00032///Lysine degradation, lysine => saccharopine => acetoacetyl-CoA","R02313///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase; N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NAD+ + H2O <=> L-Glutamate + L-2-Aminoadipate 6-semialdehyde + NADH + H++++R00716///N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)   N6-(L-1,3-Dicarboxypropyl)-L-lysine + NADP+ + H2O <=> L-Lysine + 2-Oxoglutarate + NADPH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0047130///saccharopine dehydrogenase (NADP+, L-lysine-forming) activity+++GO:0047131///saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity+++GO:0004753///saccharopine dehydrogenase activity+++GO:0016491///oxidoreductase activity+++GO:0003824///catalytic activity","GO:0019878///lysine biosynthetic process via aminoadipic acid+++GO:0033512///L-lysine catabolic process to acetyl-CoA via saccharopine+++GO:0051262///protein tetramerization+++GO:0006554///lysine catabolic process+++GO:0019477///L-lysine catabolic process+++GO:0055114///oxidation-reduction process+++GO:0008152///metabolic process","IPR005097///Saccharopine dehydrogenase, NADP binding domain+++IPR007698///Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain+++IPR036291///NAD(P)-binding domain superfamily+++IPR032095///Saccharopine dehydrogenase, C-terminal+++IPR007886///Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal","[AASS_HUMAN|Reviewed]RecName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial; AltName: Full=LKR/SDH; Includes: RecName: Full=Lysine ketoglutarate reductase; Short=LKR; Short=LOR; EC=1.5.1.8; Includes: RecName: Full=Saccharopine dehydrogenase; Short=SDH; EC=1.5.1.9; Flags: Precursor;+++[A4D0W4_HUMAN|Unreviewed]SubName: Full=Aminoadipate-semialdehyde synthase, isoform CRA_a {ECO:0000313|EMBL:EAW83564.1};+++[F8WAH1_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000351834};+++[F8WE53_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000414001};+++[H7C0C6_HUMAN|Unreviewed]SubName: Full=Alpha-aminoadipic semialdehyde synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000394180}; Flags: Fragment;"]
[10158,"'PDZK1IP1'",11,2,6.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane",null,null,"IPR031627///PDZK1-interacting protein 1/SMIM24+++IPR026628///PDZK1-interacting protein 1","[PDZ1I_HUMAN|Reviewed]RecName: Full=PDZK1-interacting protein 1; AltName: Full=17 kDa membrane-associated protein; AltName: Full=Protein DD96;"]
[10159,"'ATP6AP2'",1776,2057,1916.5,"04614///Renin-angiotensin system","H00658///Syndromic X-linked mental retardation",null,null,"GO:0044297///cell body+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0009897///external side of plasma membrane+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection","GO:0038023///signaling receptor activity+++GO:0019899///enzyme binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding","GO:0043312///neutrophil degranulation+++GO:0060323///head morphogenesis+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021903///rostrocaudal neural tube patterning+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0048069///eye pigmentation+++GO:0002003///angiotensin maturation+++GO:0043408///regulation of MAPK cascade","IPR017850///Alkaline-phosphatase-like, core domain superfamily+++IPR012493///Renin receptor-like","[RENR_HUMAN|Reviewed]RecName: Full=Renin receptor; AltName: Full=ATPase H(+)-transporting lysosomal accessory protein 2; AltName: Full=ATPase H(+)-transporting lysosomal-interacting protein 2; AltName: Full=ER-localized type I transmembrane adaptor; AltName: Full=Embryonic liver differentiation factor 10; AltName: Full=N14F; AltName: Full=Renin/prorenin receptor; AltName: Full=Vacuolar ATP synthase membrane sector-associated protein M8-9; Short=ATP6M8-9; Short=V-ATPase M8.9 subunit; Flags: Precursor;+++[A0A1B0GTB0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489622}; Flags: Fragment;+++[A0A1B0GTD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489653};+++[A0A1B0GTU8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489845};+++[A0A1B0GU12_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000489920};+++[A0A1B0GUT7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490239};+++[A0A1B0GUV3_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490257}; Flags: Fragment;+++[A0A1B0GV24_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490345};+++[A0A1B0GV60_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490382};+++[A0A1B0GVB9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490452};+++[A0A1B0GVC7_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490462};+++[A0A1B0GVI9_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490532};+++[A0A1B0GVW0_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490675};+++[A0A1B0GVZ1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490706};+++[A0A1B0GW13_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490733};+++[A0A1B0GWD6_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490884}; Flags: Fragment;+++[A0A1B0GWJ8_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000490954};+++[A0A1C7CYW4_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000367697};+++[B7Z1I9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59846, highly similar to Renin receptor {ECO:0000313|EMBL:BAH11525.1};+++[B7Z413_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52527, highly similar to Renin receptor {ECO:0000313|EMBL:BAH12399.1};+++[H7C240_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000403969}; Flags: Fragment;+++[H7C3E1_HUMAN|Unreviewed]SubName: Full=Renin receptor {ECO:0000313|Ensembl:ENSP00000411317};"]
[1016,"'CDH18'",1,1,1,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0009986///cell surface+++GO:0005913///cell-cell adherens junction+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016342///catenin complex","GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0045294///alpha-catenin binding+++GO:0070097///delta-catenin binding+++GO:0045296///cadherin binding+++GO:0005509///calcium ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0008013///beta-catenin binding","GO:0007155///cell adhesion+++GO:0034332///adherens junction organization+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0098609///cell-cell adhesion+++GO:0007043///cell-cell junction assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0044331///cell-cell adhesion mediated by cadherin","IPR002126///Cadherin-like+++IPR020894///Cadherin conserved site+++IPR000233///Cadherin, cytoplasmic domain+++IPR039808///Cadherin+++IPR015919///Cadherin-like superfamily+++IPR027397///Catenin binding domain superfamily","[CAD18_HUMAN|Reviewed]RecName: Full=Cadherin-18; AltName: Full=Cadherin-14; Flags: Precursor;+++[D6RER2_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000424931};+++[D6RIH8_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000425854};+++[H0YAK3_HUMAN|Unreviewed]SubName: Full=Cadherin-18 {ECO:0000313|Ensembl:ENSP00000427383}; Flags: Fragment;"]
[10160,"'FARP1'",1615,1630,1622.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0030054///cell junction+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0098890///extrinsic component of postsynaptic membrane+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0048365///Rac GTPase binding","GO:0007275///multicellular organism development+++GO:0098942///retrograde trans-synaptic signaling by trans-synaptic protein complex+++GO:0010923///negative regulation of phosphatase activity+++GO:1905606///regulation of presynapse assembly+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048813///dendrite morphogenesis+++GO:0007416///synapse assembly+++GO:0098974///postsynaptic actin cytoskeleton organization","IPR000299///FERM domain+++IPR001849///Pleckstrin homology domain+++IPR019747///FERM conserved site+++IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR014847///FERM adjacent (FA)+++IPR035899///Dbl homology (DH) domain superfamily+++IPR019749///Band 4.1 domain+++IPR018979///FERM, N-terminal+++IPR019748///FERM central domain+++IPR000219///Dbl homology (DH) domain+++IPR018980///FERM, C-terminal PH-like domain+++IPR000798///Ezrin/radixin/moesin-like+++IPR035963///FERM superfamily, second domain+++IPR011993///PH-like domain superfamily+++IPR029071///Ubiquitin-like domain superfamily","[FARP1_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1; AltName: Full=Chondrocyte-derived ezrin-like protein; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 1; AltName: Full=Pleckstrin homology domain-containing family C member 2; Short=PH domain-containing family C member 2;+++[A0A1B0GV68_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000490391};+++[A0A2X0TVY0_HUMAN|Unreviewed]SubName: Full=FARP1 {ECO:0000313|EMBL:SPT35756.1}; SubName: Full=FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (Chondrocyte-derived) {ECO:0000313|EMBL:EAX08982.1}; Flags: Fragment;+++[C9JME2_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000471242};+++[H0Y783_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410930}; Flags: Fragment;+++[M0QXT1_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469365}; Flags: Fragment;+++[M0QYB0_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469712}; Flags: Fragment;+++[M0R262_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472346}; Flags: Fragment;"]
[10161,"'LPAR6'",3,1,2,"04151///PI3K-Akt signaling pathway+++04072///Phospholipase D signaling pathway+++05200///Pathways in cancer+++04080///Neuroactive ligand-receptor interaction","H00667///Woolly hair+++H00784///Localized autosomal recessive hypotrichosis",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0001835///blastocyst hatching+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0035025///positive regulation of Rho protein signal transduction","IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR017452///GPCR, rhodopsin-like, 7TM","[LPAR6_HUMAN|Reviewed]RecName: Full=Lysophosphatidic acid receptor 6; Short=LPA receptor 6; Short=LPA-6; AltName: Full=Oleoyl-L-alpha-lysophosphatidic acid receptor; AltName: Full=P2Y purinoceptor 5; Short=P2Y5; AltName: Full=Purinergic receptor 5; AltName: Full=RB intron encoded G-protein coupled receptor;+++[A0A024RDT2_HUMAN|Unreviewed]SubName: Full=HCG30749, isoform CRA_a {ECO:0000313|EMBL:EAX08797.1};+++[B3KVQ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41064 fis, clone TRACH2001021, highly similar to P2Y PURINOCEPTOR 5 {ECO:0000313|EMBL:BAG53867.1};"]
[10162,"'LPCAT3'",502,488,495,"00564///Glycerophospholipid metabolism+++04216///Ferroptosis",null,null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase   Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0097006///regulation of plasma lipoprotein particle levels+++GO:0006629///lipid metabolic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling","IPR004299///Membrane bound O-acyl transferase, MBOAT","[MBOA5_HUMAN|Reviewed]RecName: Full=Lysophospholipid acyltransferase 5; Short=LPLAT 5; EC=2.3.1.-; AltName: Full=1-acylglycerophosphocholine O-acyltransferase; EC=2.3.1.23; AltName: Full=1-acylglycerophosphoserine O-acyltransferase; EC=2.3.1.n6; AltName: Full=Lysophosphatidylcholine acyltransferase; Short=LPCAT; Short=Lyso-PC acyltransferase; AltName: Full=Lysophosphatidylcholine acyltransferase 3; Short=Lyso-PC acyltransferase 3; AltName: Full=Lysophosphatidylserine acyltransferase; Short=LPSAT; Short=Lyso-PS acyltransferase; AltName: Full=Membrane-bound O-acyltransferase domain-containing protein 5; Short=O-acyltransferase domain-containing protein 5;+++[B7Z3N5_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000443166}; SubName: Full=cDNA FLJ59910, highly similar to Membrane bound O-acyltransferase domain-containing protein 5 {ECO:0000313|EMBL:BAH12271.1};+++[F5GYT3_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000440550};+++[F5H0M4_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000438765};+++[F5H680_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000437827};+++[F5H7K7_HUMAN|Unreviewed]SubName: Full=Lysophospholipid acyltransferase 5 {ECO:0000313|Ensembl:ENSP00000442454};"]
[10163,"'WASF2'",1916,2522,2219,"05132///Salmonella infection+++05231///Choline metabolism in cancer+++05131///Shigellosis+++05100///Bacterial invasion of epithelial cells+++04666///Fc gamma R-mediated phagocytosis+++04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005911///cell-cell junction+++GO:0005829///cytosol+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0031209///SCAR complex+++GO:0001726///ruffle+++GO:0005769///early endosome","GO:0045296///cadherin binding+++GO:0003779///actin binding+++GO:0017124///SH3 domain binding+++GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0035855///megakaryocyte development+++GO:0030032///lamellipodium assembly+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0001667///ameboidal-type cell migration+++GO:0030048///actin filament-based movement+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0030036///actin cytoskeleton organization+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0001525///angiogenesis+++GO:0051497///negative regulation of stress fiber assembly+++GO:0006897///endocytosis+++GO:0016601///Rac protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0072673///lamellipodium morphogenesis+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0016032///viral process","IPR028288///SCAR/WAVE family+++IPR003980///Histamine H3 receptor+++IPR003124///WH2 domain","[WASF2_HUMAN|Reviewed]RecName: Full=Wiskott-Aldrich syndrome protein family member 2; Short=WASP family protein member 2; AltName: Full=Protein WAVE-2; AltName: Full=Verprolin homology domain-containing protein 2;+++[Q05BU7_HUMAN|Unreviewed]SubName: Full=WASF2 protein {ECO:0000313|EMBL:AAH32724.1}; Flags: Fragment;"]
[10164,"'CHST4'",1,0,0.5,"00533///Glycosaminoglycan biosynthesis - keratan sulfate",{"$nulls":3},"GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0031228///intrinsic component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0008146///sulfotransferase activity+++GO:0001517///N-acetylglucosamine 6-O-sulfotransferase activity+++GO:0016740///transferase activity","GO:0006955///immune response+++GO:0006790///sulfur compound metabolic process+++GO:0007267///cell-cell signaling+++GO:0006954///inflammatory response+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0006477///protein sulfation+++GO:0016266///O-glycan processing+++GO:0007155///cell adhesion+++GO:0005975///carbohydrate metabolic process","IPR000863///Sulfotransferase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR016469///Carbohydrate sulfotransferase","[CHST4_HUMAN|Reviewed]RecName: Full=Carbohydrate sulfotransferase 4; EC=2.8.2.-; AltName: Full=Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; Short=GST-3; AltName: Full=High endothelial cells N-acetylglucosamine 6-O-sulfotransferase; Short=HEC-GlcNAc6ST; AltName: Full=L-selectin ligand sulfotransferase; Short=LSST; AltName: Full=N-acetylglucosamine 6-O-sulfotransferase 2; Short=GlcNAc6ST-2; Short=Gn6st-2;"]
[10165,"'SLC25A13'",279,340,309.5,null,"H01305///Global cerebral hypomyelination+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00185///Citrullinemia (CTLN)",null,null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion","GO:0015183///L-aspartate transmembrane transporter activity+++GO:0042802///identical protein binding+++GO:0005313///L-glutamate transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015172///acidic amino acid transmembrane transporter activity+++GO:0005509///calcium ion binding+++GO:0005215///transporter activity+++GO:0046872///metal ion binding","GO:0006839///mitochondrial transport+++GO:0015810///aspartate transmembrane transport+++GO:0055085///transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0015813///L-glutamate transmembrane transport+++GO:0045333///cellular respiration+++GO:0006851///mitochondrial calcium ion transmembrane transport+++GO:0043490///malate-aspartate shuttle+++GO:0051592///response to calcium ion+++GO:0070778///L-aspartate transmembrane transport+++GO:0006094///gluconeogenesis","IPR040062///Mitochondrial carrier domain protein+++IPR011992///EF-hand domain pair+++IPR039800///Calcium uptake protein 1/2/3+++IPR002067///Mitochondrial carrier protein+++IPR018108///Mitochondrial substrate/solute carrier+++IPR023395///Mitochondrial carrier domain superfamily+++IPR002048///EF-hand domain","[CMC2_HUMAN|Reviewed]RecName: Full=Calcium-binding mitochondrial carrier protein Aralar2; AltName: Full=Citrin; AltName: Full=Mitochondrial aspartate glutamate carrier 2; AltName: Full=Solute carrier family 25 member 13;+++[Q75KX8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07527.1}; Flags: Fragment;+++[Q75M55_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC25A13 {ECO:0000313|EMBL:AAS07513.1}; Flags: Fragment;+++[R4GN64_HUMAN|Unreviewed]SubName: Full=Calcium-binding mitochondrial carrier protein Aralar2 {ECO:0000313|Ensembl:ENSP00000473505};"]
[10166,"'SLC25A15'",91,101.37,96.185,null,"H01268///Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005664///nuclear origin of replication recognition complex+++GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0000166///nucleotide binding+++GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0022857///transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0000064///L-ornithine transmembrane transporter activity","GO:0033314///mitotic DNA replication checkpoint+++GO:1990575///mitochondrial L-ornithine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0000050///urea cycle+++GO:0006270///DNA replication initiation+++GO:0000278///mitotic cell cycle+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006260///DNA replication","IPR023395///Mitochondrial carrier domain superfamily+++IPR018108///Mitochondrial substrate/solute carrier+++IPR040062///Mitochondrial carrier domain protein","[ORNT1_HUMAN|Reviewed]RecName: Full=Mitochondrial ornithine transporter 1; AltName: Full=Solute carrier family 25 member 15;+++[F2Z354_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000431429};+++[Q5VZD9_HUMAN|Unreviewed]SubName: Full=Mitochondrial ornithine transporter 1 {ECO:0000313|Ensembl:ENSP00000415826}; Flags: Fragment;"]
[10168,"'ZNF197'",163,158,160.5,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR003309///SCAN domain+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily+++IPR038269///SCAN domain superfamily","[ZN197_HUMAN|Reviewed]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[C9JIP4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000390115}; Flags: Fragment;+++[C9JQH5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000394713}; Flags: Fragment;+++[F8WDZ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000402483};+++[F8WEU5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000334616};+++[M0QYR3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 20 {ECO:0000313|Ensembl:ENSP00000470025};+++[Q4G1C8_HUMAN|Unreviewed]SubName: Full=ZNF197 protein {ECO:0000313|EMBL:AAH17584.1}; Flags: Fragment;+++[Q7Z6G1_HUMAN|Unreviewed]SubName: Full=Znf197 truncated protein {ECO:0000313|EMBL:AAP57399.1}; Flags: Fragment;+++[Q86XA2_HUMAN|Unreviewed]SubName: Full=ZNF20 protein {ECO:0000313|EMBL:AAH45814.1};"]
[10169,"'SERF2'",7572,5665,6618.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003674///molecular_function","GO:0008150///biological_process","IPR007513///Uncharacterised protein family SERF, N-terminal","[SERF2_HUMAN|Reviewed]RecName: Full=Small EDRK-rich factor 2; AltName: Full=Gastric cancer-related protein VRG107; AltName: Full=Protein 4F5-related; Short=4F5rel; Short=h4F5rel;+++[B8ZZY7_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386316};+++[B9A031_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000387041};+++[C9JQZ0_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000394660}; Flags: Fragment;+++[F8WBN3_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000386290};+++[F8WBV6_HUMAN|Unreviewed]SubName: Full=Small EDRK-rich factor 2 {ECO:0000313|Ensembl:ENSP00000391027};"]
[1017,"'CDK2'",92,105,98.5,"04934///Cushing's syndrome+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++04914///Progesterone-mediated oocyte maturation+++05226///Gastric cancer+++05215///Prostate cancer+++04151///PI3K-Akt signaling pathway+++04114///Oocyte meiosis+++05200///Pathways in cancer+++05162///Measles+++04218///Cellular senescence+++05203///Viral carcinogenesis+++04110///Cell cycle+++05168///Herpes simplex infection+++04068///FoxO signaling pathway+++05161///Hepatitis B+++05222///Small cell lung cancer+++05169///Epstein-Barr virus infection",null,"M00692///Cell cycle - G1/S transition+++M00693///Cell cycle - G2/M transition",null,"GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0097123///cyclin A1-CDK2 complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0000805///X chromosome+++GO:0097134///cyclin E1-CDK2 complex+++GO:0000781///chromosome, telomeric region+++GO:0097124///cyclin A2-CDK2 complex+++GO:0097135///cyclin E2-CDK2 complex+++GO:0000806///Y chromosome+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000793///condensed chromosome+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0015030///Cajal body+++GO:0005856///cytoskeleton","GO:0097472///cyclin-dependent protein kinase activity+++GO:0035173///histone kinase activity+++GO:0000287///magnesium ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0000166///nucleotide binding+++GO:0019904///protein domain specific binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0046872///metal ion binding","GO:0051301///cell division+++GO:0016310///phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006260///DNA replication+++GO:0006468///protein phosphorylation+++GO:0006813///potassium ion transport+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0018105///peptidyl-serine phosphorylation+++GO:0051321///meiotic cell cycle+++GO:0006281///DNA repair+++GO:0008284///positive regulation of cell proliferation+++GO:0032298///positive regulation of DNA-dependent DNA replication initiation+++GO:0051726///regulation of cell cycle+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0007099///centriole replication+++GO:0071732///cellular response to nitric oxide+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051298///centrosome duplication+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060968///regulation of gene silencing+++GO:0007049///cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016572///histone phosphorylation","IPR008271///Serine/threonine-protein kinase, active site+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily","[CDK2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2; EC=2.7.11.22 {ECO:0000269|PubMed:1396589, ECO:0000269|PubMed:28666995, ECO:0000269|PubMed:9030781}; AltName: Full=Cell division protein kinase 2; AltName: Full=p33 protein kinase;+++[A0A024RB10_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW96857.1};+++[A0A024RB77_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2, isoform CRA_b {ECO:0000313|EMBL:EAW96860.1};+++[B4DDL9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54979, highly similar to Homo sapiens cyclin-dependent kinase 2 (CDK2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG56780.1};+++[E7ESI2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000393605};+++[G3V317_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000450983};+++[G3V5T9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2 {ECO:0000313|Ensembl:ENSP00000452514}; SubName: Full=Cyclin-dependent kinase 2, isoform CRA_c {ECO:0000313|EMBL:EAW96859.1};"]
[10171,"'RCL1'",112,92,102,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003824///catalytic activity+++GO:0004521///endoribonuclease activity","GO:0042254///ribosome biogenesis+++GO:0000447///endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006396///RNA processing+++GO:0006364///rRNA processing+++GO:0008150///biological_process+++GO:0000480///endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","IPR020719///RNA 3'-terminal phosphate cyclase-like, conserved site+++IPR013792///RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta+++IPR013791///RNA 3'-terminal phosphate cyclase, insert domain+++IPR016443///RNA 3'-terminal phosphate cyclase type 2+++IPR000228///RNA 3'-terminal phosphate cyclase+++IPR037136///RNA 3'-terminal phosphate cyclase domain superfamily+++IPR023797///RNA 3'-terminal phosphate cyclase domain+++IPR036553///RNA 3'-terminal phosphate cyclase, insert domain superfamily","[RCL1_HUMAN|Reviewed]RecName: Full=RNA 3'-terminal phosphate cyclase-like protein;+++[Q5VYW8_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000371151};+++[Q5VZU2_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000413381}; Flags: Fragment;+++[Q5VZU3_HUMAN|Unreviewed]SubName: Full=RNA 3'-terminal phosphate cyclase-like protein {ECO:0000313|Ensembl:ENSP00000412000};"]
[10172,"'ZNF256'",25,30,27.5,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR039938///Zinc finger protein 781+++IPR036236///Zinc finger C2H2 superfamily","[ZN256_HUMAN|Reviewed]RecName: Full=Zinc finger protein 256; AltName: Full=Bone marrow zinc finger 3; Short=BMZF-3;+++[L8E7T8_HUMAN|Unreviewed]SubName: Full=Alternative protein ZNF256 {ECO:0000313|EMBL:CCQ43335.1};+++[M0R2X0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 256 {ECO:0000313|Ensembl:ENSP00000472858};"]
[10174,"'SORBS3'",2962,3065,3013.5,"04022///cGMP-PKG signaling pathway+++04662///B cell receptor signaling pathway+++04114///Oocyte meiosis+++04140///Autophagy - animal+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04728///Dopaminergic synapse+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++04720///Long-term potentiation+++05014///Amyotrophic lateral sclerosis (ALS)+++04724///Glutamatergic synapse+++04380///Osteoclast differentiation+++04218///Cellular senescence+++05010///Alzheimer's disease+++04137///Mitophagy - animal+++04658///Th1 and Th2 cell differentiation+++04660///T cell receptor signaling pathway+++04659///Th17 cell differentiation+++04360///Axon guidance+++04922///Glucagon signaling pathway+++04924///Renin secretion+++04370///VEGF signaling pathway+++04010///MAPK signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05031///Amphetamine addiction+++04310///Wnt signaling pathway+++04020///Calcium signaling pathway+++04625///C-type lectin receptor signaling pathway+++05166///HTLV-I infection+++04921///Oxytocin signaling pathway","H02150///Infantile or early childhood epileptic encephalopathy",null,null,"GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005856///cytoskeleton","GO:0017166///vinculin binding+++GO:0005515///protein binding+++GO:0005200///structural constituent of cytoskeleton+++GO:0008134///transcription factor binding","GO:0051495///positive regulation of cytoskeleton organization+++GO:0006936///muscle contraction+++GO:0043410///positive regulation of MAPK cascade+++GO:0051496///positive regulation of stress fiber assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0031589///cell-substrate adhesion+++GO:0007015///actin filament organization+++GO:0007155///cell adhesion","IPR003127///SoHo domain+++IPR035608///Vinexin, SH3 domain 2+++IPR001452///SH3 domain+++IPR036028///SH3-like domain superfamily+++IPR028510///Vinexin+++IPR035607///Vinexin, SH3 domain 3+++IPR035609///Vinexin, SH3 domain 1","[VINEX_HUMAN|Reviewed]RecName: Full=Vinexin; AltName: Full=SH3-containing adapter molecule 1; Short=SCAM-1; AltName: Full=Sorbin and SH3 domain-containing protein 3;+++[E5RIA0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429479}; Flags: Fragment;+++[E5RJP2_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000431128}; Flags: Fragment;+++[E7EQH0_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000429723};+++[H0YAU6_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428102}; Flags: Fragment;+++[H0YAZ3_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428327}; Flags: Fragment;+++[H0YB51_HUMAN|Unreviewed]SubName: Full=Vinexin {ECO:0000313|Ensembl:ENSP00000428678}; Flags: Fragment;+++[Q9BT70_HUMAN|Unreviewed]SubName: Full=SORBS3 protein {ECO:0000313|EMBL:AAH04314.1}; Flags: Fragment;"]
[10175,"'CNIH1'",384,405,394.5,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0012507///ER to Golgi transport vesicle membrane",null,"GO:0006955///immune response+++GO:0007165///signal transduction+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","IPR033466///Cornichon, conserved site+++IPR003377///Cornichon","[CNIH1_HUMAN|Reviewed]RecName: Full=Protein cornichon homolog 1; Short=CNIH-1; AltName: Full=Cornichon family AMPA receptor auxiliary protein 1; AltName: Full=Protein cornichon homolog; AltName: Full=T-cell growth-associated molecule 77; Short=TGAM77;+++[A8MVW4_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_b {ECO:0000313|EMBL:EAW80636.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000378940};+++[B2R4P1_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW80635.1}; SubName: Full=cDNA FLJ90300 fis, clone NT2RP2000533, highly similar to Cornichon homolog {ECO:0000313|EMBL:BAG52000.1}; SubName: Full=cDNA, FLJ92163, Homo sapiens cornichon homolog (Drosophila) (CNIH), mRNA {ECO:0000313|EMBL:BAG34838.1};+++[G3V3B2_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451142};+++[G3V474_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451640};+++[G3V4K0_HUMAN|Unreviewed]SubName: Full=Cornichon homolog (Drosophila), isoform CRA_c {ECO:0000313|EMBL:EAW80637.1}; SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000451852};+++[G3V5P8_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452457};+++[G3V5Q6_HUMAN|Unreviewed]SubName: Full=Protein cornichon homolog 1 {ECO:0000313|Ensembl:ENSP00000452466};"]
[10178,"'TENM1'",1,1,1,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0043005///neuron projection+++GO:0016363///nuclear matrix+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016607///nuclear speck+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm","GO:0046982///protein heterodimerization activity+++GO:0008201///heparin binding+++GO:0042803///protein homodimerization activity+++GO:0050839///cell adhesion molecule binding","GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0006955///immune response+++GO:0007218///neuropeptide signaling pathway+++GO:0090316///positive regulation of intracellular protein transport+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007165///signal transduction+++GO:0043406///positive regulation of MAP kinase activity+++GO:0008285///negative regulation of cell proliferation+++GO:0051491///positive regulation of filopodium assembly+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0048666///neuron development+++GO:0007399///nervous system development","IPR009471///Teneurin intracellular, N-terminal+++IPR000742///EGF-like domain+++IPR006530///YD repeat+++IPR013032///EGF-like, conserved site+++IPR028916///Tox-GHH domain+++IPR011042///Six-bladed beta-propeller, TolB-like+++IPR027688///Teneurin-1/4","[TEN1_HUMAN|Reviewed]RecName: Full=Teneurin-1; Short=Ten-1; AltName: Full=Protein Odd Oz/ten-m homolog 1; AltName: Full=Tenascin-M1; Short=Ten-m1; AltName: Full=Teneurin transmembrane protein 1; Contains: RecName: Full=Ten-1 intracellular domain; Short=IDten-1; Short=Ten-1 ICD; Contains: RecName: Full=Teneurin C-terminal-associated peptide; Short=TCPA-1; AltName: Full=Ten-1 extracellular domain; Short=Ten-1 ECD;+++[B7ZMH4_HUMAN|Unreviewed]SubName: Full=ODZ1 protein {ECO:0000313|EMBL:AAI44544.1};+++[G3CAS6_HUMAN|Unreviewed]SubName: Full=Odz, odd Oz/ten-m homolog 1 (Drosophila) {ECO:0000313|EMBL:CCD17865.1}; Flags: Fragment;+++[L8EAN5_HUMAN|Unreviewed]SubName: Full=Alternative protein ODZ1 {ECO:0000313|EMBL:CCQ43428.1};"]
[10179,"'RBM7'",254.02,284,269.01,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0005515///protein binding","GO:0051321///meiotic cell cycle+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain+++IPR035979///RNA-binding domain superfamily+++IPR034500///RBM7, RNA recognition motif","[RBM7_HUMAN|Reviewed]RecName: Full=RNA-binding protein 7; AltName: Full=RNA-binding motif protein 7;+++[F5GXV8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440949};+++[F5GY08_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000440923};+++[F5H606_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437998};+++[F5H674_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000437847};+++[G3V1T9_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_a {ECO:0000313|EMBL:EAW67246.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000445848};+++[J3KPD3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7, isoform CRA_c {ECO:0000313|EMBL:EAW67248.1}; SubName: Full=RNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000364639};+++[Q6IRX3_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 7 {ECO:0000313|EMBL:AAH70262.1};"]
[1018,"'CDK3'",62,65,63.5,{"$nulls":4},"GO:0005634///nucleus","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0045023///G0 to G1 transition+++GO:0007049///cell cycle+++GO:0006468///protein phosphorylation+++GO:0008283///cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051301///cell division+++GO:0016310///phosphorylation","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[CDK3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 3; EC=2.7.11.22; AltName: Full=Cell division protein kinase 3;+++[A0A024R8R3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3, isoform CRA_a {ECO:0000313|EMBL:EAW89354.1};+++[K7EJ83_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000465062}; Flags: Fragment;+++[K7ELV5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 3 {ECO:0000313|Ensembl:ENSP00000466237}; Flags: Fragment;"]
[10180,"'RBM6'",609,537,573,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006396///RNA processing","IPR000467///G-patch domain+++IPR034123///RBM6, RNA recognition motif 1+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR028806///RNA-binding protein 6+++IPR034125///RBM6, RNA recognition motif 2+++IPR035617///RBM6, OCRE domain+++IPR035979///RNA-binding domain superfamily+++IPR000504///RNA recognition motif domain","[RBM6_HUMAN|Reviewed]RecName: Full=RNA-binding protein 6; AltName: Full=Lung cancer antigen NY-LU-12; AltName: Full=Protein G16; AltName: Full=RNA-binding motif protein 6; AltName: Full=RNA-binding protein DEF-3;+++[A8K6Q4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76888, highly similar to Homo sapiens RNA binding motif protein 6 (RBM6), mRNA {ECO:0000313|EMBL:BAF84408.1};+++[C9J250_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000392475};+++[C9JII0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000403865}; Flags: Fragment;+++[C9JMC8_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000389763}; Flags: Fragment;+++[C9JSL1_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000394336}; Flags: Fragment;+++[E9PGM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396466};+++[F8WCA5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000406548};+++[F8WCT0_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000396410};+++[F8WF63_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 6 {ECO:0000313|Ensembl:ENSP00000399942};"]
[10181,"'RBM5'",967,956,961.5,null,"H00943///TARP syndrome",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0008380///RNA splicing+++GO:0008285///negative regulation of cell proliferation+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006915///apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0000245///spliceosomal complex assembly+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0042981///regulation of apoptotic process+++GO:0043065///positive regulation of apoptotic process","IPR000467///G-patch domain+++IPR034993///RNA-binding protein 5, RNA recognition motif 2+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain+++IPR033094///RNA-binding protein 5+++IPR036443///Zinc finger, RanBP2-type superfamily+++IPR001876///Zinc finger, RanBP2-type+++IPR013087///Zinc finger C2H2-type+++IPR035979///RNA-binding domain superfamily+++IPR034991///RNA-binding protein 5, RNA recognition motif 1","[RBM5_HUMAN|Reviewed]RecName: Full=RNA-binding protein 5; AltName: Full=Protein G15; AltName: Full=Putative tumor suppressor LUCA15; AltName: Full=RNA-binding motif protein 5; AltName: Full=Renal carcinoma antigen NY-REN-9;+++[A0A024R2U6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW65042.1};+++[A0A0S2Z549_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 1 {ECO:0000313|EMBL:ALQ33963.1}; Flags: Fragment;+++[A0A0S2Z5U0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 5 isoform 2 {ECO:0000313|EMBL:ALQ33964.1};+++[C9J9P7_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000406119}; Flags: Fragment;+++[C9JFQ5_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000390711}; Flags: Fragment;+++[C9JR02_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000394622}; Flags: Fragment;+++[E1CJT4_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 variant {ECO:0000313|EMBL:BAJ19019.1};+++[F8W910_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000384872}; Flags: Fragment;+++[F8WE23_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000414218};+++[H7BYM9_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 5 {ECO:0000313|Ensembl:ENSP00000378603}; Flags: Fragment;"]
[10184,"'LHFPL2'",600,670,635,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0031092///platelet alpha granule membrane+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0007338///single fertilization+++GO:1905516///positive regulation of fertilization+++GO:0002576///platelet degranulation+++GO:0046545///development of primary female sexual characteristics+++GO:0008150///biological_process+++GO:0046546///development of primary male sexual characteristics","IPR019372///Lipoma HMGIC fusion partner-like protein","[LHPL2_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 2 protein {ECO:0000312|HGNC:HGNC:6588}; AltName: Full=Lipoma HMGIC fusion partner-like 2 protein {ECO:0000312|HGNC:HGNC:6588};+++[A0A024RAM8_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW95819.1};"]
[10186,"'LHFPL6'",571,486,528.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","IPR019372///Lipoma HMGIC fusion partner-like protein","[LHPL6_HUMAN|Reviewed]RecName: Full=LHFPL tetraspan subfamily member 6 protein {ECO:0000312|HGNC:HGNC:6586}; AltName: Full=Lipoma HMGIC fusion partner {ECO:0000312|HGNC:HGNC:6586}; Flags: Precursor;+++[A0A024RDR1_HUMAN|Unreviewed]SubName: Full=Lipoma HMGIC fusion partner, isoform CRA_a {ECO:0000313|EMBL:EAX08617.1};"]
[10188,"'TNK2'",1273,1516,1394.5,{"$nulls":4},"GO:0005912///adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0097268///cytoophidium+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0070436///Grb2-EGFR complex+++GO:0005634///nucleus+++GO:0030136///clathrin-coated vesicle+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005905///clathrin-coated pit","GO:0016740///transferase activity+++GO:0005095///GTPase inhibitor activity+++GO:0042802///identical protein binding+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0050699///WW domain binding+++GO:0046872///metal ion binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0007264///small GTPase mediated signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0034260///negative regulation of GTPase activity+++GO:0030154///cell differentiation+++GO:0006897///endocytosis+++GO:0007165///signal transduction+++GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation","IPR021619///Mig-6 domain+++IPR037085///Cdc42 binding domain-like superfamily+++IPR015116///Cdc42 binding domain-like+++IPR001452///SH3 domain+++IPR030220///Activated CDC42 kinase 1+++IPR008266///Tyrosine-protein kinase, active site+++IPR009060///UBA-like superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR036028///SH3-like domain superfamily+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR020635///Tyrosine-protein kinase, catalytic domain+++IPR011009///Protein kinase-like domain superfamily","[ACK1_HUMAN|Reviewed]RecName: Full=Activated CDC42 kinase 1; Short=ACK-1; EC=2.7.10.2 {ECO:0000269|PubMed:10652228, ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:16472662, ECO:0000269|PubMed:18993068, ECO:0000269|PubMed:20333297}; EC=2.7.11.1 {ECO:0000269|PubMed:16257963, ECO:0000269|PubMed:18993068}; AltName: Full=Tyrosine kinase non-receptor protein 2;+++[B3KXJ4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45547 fis, clone BRTHA2035743, highly similar to Activated CDC42 kinase 1 {ECO:0000313|EMBL:BAG54506.1};+++[C9J1X3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392546};+++[C9JDG3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000395154}; Flags: Fragment;+++[C9JIR5_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390088}; Flags: Fragment;+++[F8WER3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000393707};+++[H0Y5H7_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000398614}; Flags: Fragment;+++[H7BZM8_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000390435}; Flags: Fragment;+++[H7BZZ3_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000392253}; Flags: Fragment;+++[H7C343_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000409462}; Flags: Fragment;+++[H7C412_HUMAN|Unreviewed]SubName: Full=Activated CDC42 kinase 1 {ECO:0000313|Ensembl:ENSP00000415126}; Flags: Fragment;"]
[10189,"'ALYREF'",934,691,812.5,"03013///RNA transport+++03040///Spliceosome+++05168///Herpes simplex infection+++03015///mRNA surveillance pathway",null,"M00406///TREX complex+++M00430///Exon junction complex (EJC)",null,"GO:0005681///spliceosomal complex+++GO:0070062///extracellular exosome+++GO:0000346///transcription export complex+++GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0000784///nuclear chromosome, telomeric region+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0031124///mRNA 3'-end processing+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0001649///osteoblast differentiation+++GO:0051028///mRNA transport+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0016032///viral process+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000018///regulation of DNA recombination+++GO:0031297///replication fork processing","IPR035979///RNA-binding domain superfamily+++IPR025715///Chromatin target of PRMT1 protein, C-terminal+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain","[THOC4_HUMAN|Reviewed]RecName: Full=THO complex subunit 4; Short=Tho4; AltName: Full=Ally of AML-1 and LEF-1; AltName: Full=Aly/REF export factor; AltName: Full=Transcriptional coactivator Aly/REF; AltName: Full=bZIP-enhancing factor BEF;+++[E9PB61_HUMAN|Unreviewed]SubName: Full=THO complex subunit 4 {ECO:0000313|Ensembl:ENSP00000421592};"]
[1019,"'CDK4'",1459.01,1032,1245.505,"05200///Pathways in cancer+++05162///Measles+++05223///Non-small cell lung cancer+++04115///p53 signaling pathway+++05166///HTLV-I infection+++05224///Breast cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05222///Small cell lung cancer+++05165///Human papillomavirus infection+++04110///Cell cycle+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++05219///Bladder cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05161///Hepatitis B+++04218///Cellular senescence+++05212///Pancreatic cancer+++05218///Melanoma+++05225///Hepatocellular carcinoma+++01522///Endocrine resistance+++05163///Human cytomegalovirus infection+++05220///Chronic myeloid leukemia+++05214///Glioma+++04660///T cell receptor signaling pathway+++04530///Tight junction+++04934///Cushing's syndrome","H00042///Glioma+++H00030///Cervical cancer+++H00038///Melanoma","M00692///Cell cycle - G1/S transition",null,"GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005730///nucleolus+++GO:0097129///cyclin D2-CDK4 complex+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0000785///chromatin+++GO:0005923///bicellular tight junction+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005667///transcription factor complex","GO:0030332///cyclin binding+++GO:0016740///transferase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0044877///protein-containing complex binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0071157///negative regulation of cell cycle arrest+++GO:0046890///regulation of lipid biosynthetic process+++GO:0033574///response to testosterone+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0032869///cellular response to insulin stimulus+++GO:0071353///cellular response to interleukin-4+++GO:0050994///regulation of lipid catabolic process+++GO:0060612///adipose tissue development+++GO:1904628///cellular response to phorbol 13-acetate 12-myristate+++GO:0010033///response to organic substance+++GO:0043065///positive regulation of apoptotic process+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0002088///lens development in camera-type eye+++GO:0016310///phosphorylation+++GO:0010468///regulation of gene expression+++GO:0006468///protein phosphorylation+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042127///regulation of cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007623///circadian rhythm+++GO:0055093///response to hyperoxia+++GO:0045727///positive regulation of translation+++GO:0045793///positive regulation of cell size+++GO:0051301///cell division+++GO:0007165///signal transduction+++GO:0040014///regulation of multicellular organism growth+++GO:0031100///animal organ regeneration+++GO:0046626///regulation of insulin receptor signaling pathway+++GO:1904637///cellular response to ionomycin+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010288///response to lead ion+++GO:0009636///response to toxic substance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[CDK4_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4; EC=2.7.11.22; AltName: Full=Cell division protein kinase 4; AltName: Full=PSK-J3;+++[A0A024RBB6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4, isoform CRA_a {ECO:0000313|EMBL:EAW97060.1};+++[F8VTV8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448098};+++[F8VWX7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449179}; Flags: Fragment;+++[F8VXD2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000449391}; Flags: Fragment;+++[F8VYH9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448963}; Flags: Fragment;+++[F8VYY1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000448885};+++[F8VZ13_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447005};+++[F8VZ51_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447779}; Flags: Fragment;+++[F8VZZ0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000447274}; Flags: Fragment;+++[F8W1L8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000446763}; Flags: Fragment;+++[Q6LC83_HUMAN|Unreviewed]SubName: Full=Cyclin dependent protein kinase {ECO:0000313|EMBL:AAB50213.1}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_b {ECO:0000313|EMBL:EAW97059.1};+++[Q96BE9_HUMAN|Unreviewed]SubName: Full=CDK4 protein {ECO:0000313|EMBL:AAH15669.1}; SubName: Full=Cyclin-dependent kinase 4 {ECO:0000313|Ensembl:ENSP00000316889}; SubName: Full=Cyclin-dependent kinase 4, isoform CRA_c {ECO:0000313|EMBL:EAW97061.1};"]
[10190,"'TXNDC9'",360,330,345,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0008150///biological_process+++GO:0045454///cell redox homeostasis","IPR013766///Thioredoxin domain+++IPR036249///Thioredoxin-like superfamily","[TXND9_HUMAN|Reviewed]RecName: Full=Thioredoxin domain-containing protein 9; AltName: Full=ATP-binding protein associated with cell differentiation; AltName: Full=Protein 1-4;+++[B8ZZX4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000386889}; Flags: Fragment;+++[F8WBV5_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000391046};+++[F8WCJ3_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000406388};+++[G3XAJ4_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain containing 9, isoform CRA_a {ECO:0000313|EMBL:EAX01868.1}; SubName: Full=Thioredoxin domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000402827};"]
[101927245,"'LOC101927245'",14,14,14,{"$nulls":8},"[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927262,"'LOC101927262'",0,1,0.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0030971///receptor tyrosine kinase binding+++GO:0030298///receptor signaling protein tyrosine kinase activator activity","GO:0070378///positive regulation of ERK5 cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0010976///positive regulation of neuron projection development","IPR019351///Protein of unknown function DUF2039+++IPR029364///ALK and LTK ligand FAM150","[ALKL1_HUMAN|diamond]RecName: Full=ALK and LTK ligand 1 {ECO:0000312|HGNC:HGNC:33775}; AltName: Full=Augmentor beta {ECO:0000303|PubMed:26630010}; Short=AUG-beta {ECO:0000303|PubMed:26630010}; AltName: Full=Protein FAM150A; Flags: Precursor;+++[ALKL1_MOUSE|diamond]RecName: Full=ALK and LTK ligand 1; AltName: Full=Augmentor beta; AltName: Full=Protein FAM150A; Flags: Precursor;+++[ALKL2_HUMAN|diamond]RecName: Full=ALK and LTK ligand 2 {ECO:0000312|HGNC:HGNC:27683}; AltName: Full=Augmentor alpha {ECO:0000303|PubMed:26630010}; Short=AUG-alpha {ECO:0000303|PubMed:26630010}; AltName: Full=Protein FAM150B; Flags: Precursor;+++[ALKL2_MOUSE|diamond]RecName: Full=ALK and LTK ligand 2; AltName: Full=Protein FAM150B; Flags: Precursor;+++[ALKL2_RAT|diamond]RecName: Full=ALK and LTK ligand 2; AltName: Full=Protein FAM150B; Flags: Precursor;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[MST2_DROHY|diamond]RecName: Full=Axoneme-associated protein mst101(2);+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927322,"'LOC101927322'",7,6,6.5,"04625///C-type lectin receptor signaling pathway+++04660///T cell receptor signaling pathway+++05152///Tuberculosis+++04064///NF-kappa B signaling pathway+++04662///B cell receptor signaling pathway",{"$nulls":3},"GO:0005730///nucleolus+++GO:0001650///fibrillar center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0032449///CBM complex+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0002020///protease binding+++GO:0043621///protein self-association+++GO:0042802///identical protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008233///peptidase activity","GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0002726///positive regulation of T cell cytokine production+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006508///proteolysis+++GO:0050852///T cell receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0031398///positive regulation of protein ubiquitination+++GO:2000321///positive regulation of T-helper 17 cell differentiation+++GO:0051259///protein complex oligomerization+++GO:0001923///B-1 B cell differentiation+++GO:0009620///response to fungus+++GO:0002237///response to molecule of bacterial origin+++GO:0043066///negative regulation of apoptotic process+++GO:0045087///innate immune response+++GO:0051168///nuclear export+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0042098///T cell proliferation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0050856///regulation of T cell receptor signaling pathway+++GO:0006952///defense response+++GO:0032743///positive regulation of interleukin-2 production","IPR011029///Death-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR029030///Caspase-like domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003599///Immunoglobulin subtype+++IPR033540///Mucosa-associated lymphoid tissue lymphoma translocation protein 1+++IPR037940///MALT1, death domain+++IPR003598///Immunoglobulin subtype 2+++IPR001309///Peptidase C14,  p20 domain","[MALT1_HUMAN|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1; EC=3.4.22.-; AltName: Full=MALT lymphoma-associated translocation; AltName: Full=Paracaspase;+++[MALT1_MOUSE|diamond]RecName: Full=Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog; EC=3.4.22.-; AltName: Full=Paracaspase;"]
[101927345,"'LOC101927345'",111.94,127.92,119.93,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"IPR039497///CCDC144C-like, coiled-coil domain","[A2012_HUMAN|diamond]RecName: Full=Putative ankyrin repeat domain-containing protein 20A12 pseudogene {ECO:0000305};+++[AN18A_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18A;+++[AN18B_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 18B;+++[ANR26_HUMAN|diamond]RecName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000305};+++[C144A_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 144A;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[SNX18_MOUSE|diamond]RecName: Full=Sorting nexin-18; AltName: Full=Sorting nexin-associated Golgi protein 1;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927423,"'PANO1'",35,19,27,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus",null,"GO:0031647///regulation of protein stability+++GO:0006915///apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process",null,"[PANO1_HUMAN|Reviewed]RecName: Full=Proapoptotic nucleolar protein 1 {ECO:0000303|PubMed:22094112, ECO:0000312|HGNC:HGNC:51237};"]
[101927506,"'LOC101927506'",86,100,93,"01100///Metabolic pathways+++04137///Mitophagy - animal+++00380///Tryptophan metabolism+++04140///Autophagy - animal",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin+++R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0005525///GTP binding","GO:0006310///DNA recombination+++GO:0007049///cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division+++GO:0032199///reverse transcription involved in RNA-mediated transposition","IPR016491///Septin+++IPR013544///Domain of unknown function DUF1725+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR030379///Septin-type guanine nucleotide-binding (G) domain+++IPR031751///Protein of unknown function DUF4735+++IPR000477///Reverse transcriptase domain+++IPR005135///Endonuclease/exonuclease/phosphatase","[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NP10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Np9 protein; AltName: Full=HERV-K10 Np9 protein; AltName: Full=HERV-K107 Np9 protein; AltName: Full=HERV-K_5q33.3 provirus Np9 protein;+++[NP24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Np9 protein; AltName: Full=HERV-K101 Np9 protein; AltName: Full=HERV-K_22q11.21 provirus Np9 protein;+++[NP5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Np9 protein; AltName: Full=Endogenous retrovirus K protein 5; AltName: Full=HERV-K(II) Np9 protein; AltName: Full=HERV-K_3q12.3 provirus Np9 protein;+++[NP7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Np9 protein; AltName: Full=HERV-K(III) Np9 protein; AltName: Full=HERV-K102 Np9 protein; AltName: Full=HERV-K_1q22 provirus Np9 protein;+++[PRORY_HUMAN|diamond]RecName: Full=Proline-rich protein, Y-linked;+++[RL23A_BOVIN|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_HUMAN|diamond]RecName: Full=60S ribosomal protein L23a; AltName: Full=Large ribosomal subunit protein uL23 {ECO:0000303|PubMed:24524803};+++[RL23A_MOUSE|diamond]RecName: Full=60S ribosomal protein L23a;+++[RL23A_RAT|diamond]RecName: Full=60S ribosomal protein L23a;+++[SEP14_BOVIN|diamond]RecName: Full=Septin-14;+++[SEP14_HUMAN|diamond]RecName: Full=Septin-14;+++[SEP14_MOUSE|diamond]RecName: Full=Septin-14;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101927509,"'LOC101927509'",30,46,38,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","IPR001005///SANT/Myb domain+++IPR009057///Homeobox-like domain superfamily+++IPR015395///C-myb, C-terminal+++IPR012642///Transcription regulator Wos2-domain+++IPR017930///Myb domain","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[101927601,"'GOLGA6L19'",1.36,4.4,2.88,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"IPR024858///Golgin subfamily A+++IPR026737///Golgin subfamily A member 6-like","[GG6LS_HUMAN|Reviewed]RecName: Full=Putative golgin subfamily A member 6-like protein 19;"]
[101927655,"'ZASP'",9.85,0,4.925,{"$nulls":8},"[E3Q1N2_HUMAN|Unreviewed]SubName: Full=ZO-2 associated speckle protein {ECO:0000313|EMBL:CBX53310.1};"]
[101927789,"'LOC101927789'",28,23,25.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated","IPR000626///Ubiquitin domain+++IPR029071///Ubiquitin-like domain superfamily","[GT2D2_BOVIN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GT2D2_MOUSE|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2; Short=GTF2I repeat domain-containing protein 2; AltName: Full=Transcription factor GTF2IRD2;+++[GTD2A_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2A; Short=GTF2I repeat domain-containing protein 2A; AltName: Full=Transcription factor GTF2IRD2-alpha;+++[GTD2B_HUMAN|diamond]RecName: Full=General transcription factor II-I repeat domain-containing protein 2B; Short=GTF2I repeat domain-containing protein 2B; AltName: Full=Transcription factor GTF2IRD2-beta;+++[NANGN_HUMAN|diamond]RecName: Full=NANOG neighbor homeobox; AltName: Full=Homeobox protein C14;+++[OR1FC_HUMAN|diamond]RecName: Full=Olfactory receptor 1F12; AltName: Full=Hs6M1-35P;+++[UBIML_HUMAN|diamond]RecName: Full=Putative ubiquitin-like protein FUBI-like protein ENSP00000310146;+++[UBIM_MOUSE|diamond]RecName: Full=Ubiquitin-like protein FUBI; AltName: Full=Monoclonal non-specific suppressor factor beta; Short=MNSF-beta;+++[UBIM_MUSSI|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_PIG|diamond]RecName: Full=Ubiquitin-like protein FUBI;+++[UBIM_RAT|diamond]RecName: Full=Ubiquitin-like protein FUBI;"]
[101927824,"'LOC101927824'",1,0,0.5,{"$nulls":8},"[A0A1D5R5M3_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000055611};+++[A0A2K5TP44_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000001824};+++[A0A2K5UCW2_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000010203};+++[I7G9B2_MACFA|diamond]SubName: Full=Macaca fascicularis brain cDNA clone: QtrA-16029, similar to human glycoprotein VI (platelet) (GP6), mRNA, RefSeq: NM_016363.3 {ECO:0000313|EMBL:BAE91381.1};+++[Q95K85_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:BAB60791.1};"]
[101928095,"'LOC101928095'",14.05,16,15.025,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0003677///DNA binding+++GO:0004984///olfactory receptor activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0008270///zinc ion binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0015074///DNA integration+++GO:0050911///detection of chemical stimulus involved in sensory perception of smell+++GO:0006310///DNA recombination","IPR002156///Ribonuclease H domain+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR010661///Reverse transcriptase thumb+++IPR001584///Integrase, catalytic core+++IPR003308///Integrase, N-terminal zinc-binding domain+++IPR012337///Ribonuclease H-like superfamily+++IPR036862///Integrase, C-terminal domain superfamily, retroviral+++IPR017856///Integrase-like, N-terminal+++IPR029104///Retro-transcribing virus envelope glycoprotein+++IPR017452///GPCR, rhodopsin-like, 7TM+++IPR031751///Protein of unknown function DUF4735+++IPR001037///Integrase, C-terminal, retroviral+++IPR036397///Ribonuclease H superfamily+++IPR000725///Olfactory receptor+++IPR000477///Reverse transcriptase domain","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[O7E24_HUMAN|diamond]RecName: Full=Olfactory receptor 7E24; AltName: Full=Olfactory receptor OR19-14;+++[OLF18_MOUSE|diamond]RecName: Full=Olfactory receptor 18; AltName: Full=Olfactory receptor 145-1; AltName: Full=Olfactory receptor TPCR34;+++[OR7AA_HUMAN|diamond]RecName: Full=Olfactory receptor 7A10; AltName: Full=OST027; AltName: Full=Olfactory receptor OR19-18;+++[OR7C2_HUMAN|diamond]RecName: Full=Olfactory receptor 7C2; AltName: Full=Olfactory receptor 19-18; Short=OR19-18; AltName: Full=Olfactory receptor 7C3; AltName: Full=Olfactory receptor OR19-22;+++[OR7D4_HUMAN|diamond]RecName: Full=Olfactory receptor 7D4; AltName: Full=OR19-B; AltName: Full=Odorant receptor family subfamily D member 4RT; AltName: Full=Olfactory receptor OR19-7;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[101928120,"'LOC101928120'",10,13,11.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:1990907///beta-catenin-TCF complex","GO:0035034///histone acetyltransferase regulator activity+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0030879///mammary gland development+++GO:0048589///developmental growth+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0001701///in utero embryonic development+++GO:0035563///positive regulation of chromatin binding+++GO:0002088///lens development in camera-type eye+++GO:0001822///kidney development+++GO:0009791///post-embryonic development+++GO:0060070///canonical Wnt signaling pathway+++GO:0060021///roof of mouth development+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0007420///brain development+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0007289///spermatid nucleus differentiation","IPR001965///Zinc finger, PHD-type+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR019787///Zinc finger, PHD-finger","[PYGO2_HUMAN|diamond]RecName: Full=Pygopus homolog 2;"]
[101928422,"'LOC101928422'",55.91,80.16,68.035,{"$nulls":4},"GO:0030054///cell junction+++GO:0005886///plasma membrane","GO:0044325///ion channel binding","GO:0090314///positive regulation of protein targeting to membrane+++GO:0030335///positive regulation of cell migration+++GO:0010360///negative regulation of anion channel activity","IPR029062///Class I glutamine amidotransferase-like+++IPR031161///Peptidase family M60 domain+++IPR035423///M60-like domain, N-terminal","[TCAF1_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF1_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[TCAF1_PONAB|diamond]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2}; AltName: Full=TRP channel-associated factor 1 {ECO:0000250|UniProtKB:Q9Y4C2};+++[TCAF2_BOVIN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF2_HUMAN|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 2 {ECO:0000303|PubMed:25559186};+++[TCAF2_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2}; AltName: Full=TRP channel-associated factor 2 {ECO:0000250|UniProtKB:A6NFQ2};+++[TCAF3_MOUSE|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000312|MGI:MGI:3042585}; AltName: Full=Experimental autoimmune prostatitis antigen 2;+++[TCAF3_RAT|diamond]RecName: Full=TRPM8 channel-associated factor 3 {ECO:0000305}; AltName: Full=Experimental autoimmune prostatitis antigen 2 homolog;"]
[101928527,"'PIGBOS1'",70,59,64.5,{"$nulls":4},"GO:0005576///extracellular region",{"$nulls":3},"[PIOS1_HUMAN|Reviewed]RecName: Full=Protein PIGBOS1 {ECO:0000305}; AltName: Full=PIGB opposite strand protein {ECO:0000312|HGNC:HGNC:50696}; Flags: Precursor;+++[A0A087WXK0_HUMAN|Unreviewed]SubName: Full=Protein PIGBOS1 {ECO:0000313|Ensembl:ENSP00000481097}; Flags: Fragment;"]
[101928589,"'LOC101928589'",118.08,75.66,96.87,{"$nulls":8},"[A0A2Y9R3X6_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC111821147 {ECO:0000313|RefSeq:XP_023590205.1};+++[D3DUY5_HUMAN|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAX02668.1}; Flags: Fragment;+++[G7NT51_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH30994.1}; Flags: Fragment;+++[G7Q3G6_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EHH61145.1}; Flags: Fragment;+++[Q9NXL7_HUMAN|diamond]SubName: Full=cDNA FLJ20173 fis, clone COL09814 {ECO:0000313|EMBL:BAA90993.1};"]
[101928592,"'LOC101928592'",1,5,3,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated","IPR038269///SCAN domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily+++IPR003309///SCAN domain","[ZFP2_HUMAN|diamond]RecName: Full=Zinc finger protein 2 homolog; Short=Zfp-2; AltName: Full=Zinc finger protein 751;+++[ZFP2_MOUSE|diamond]RecName: Full=Zinc finger protein 2; Short=Zfp-2; AltName: Full=Protein mKR2;+++[ZKSC1_MOUSE|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;+++[ZKSC1_PONAB|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;+++[ZKSC7_HUMAN|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 7; AltName: Full=Zinc finger protein 167; AltName: Full=Zinc finger protein 448; AltName: Full=Zinc finger protein 64;+++[ZKSC8_PANTR|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 8; AltName: Full=Zinc finger protein 192;+++[ZN180_HUMAN|diamond]RecName: Full=Zinc finger protein 180; AltName: Full=HHZ168;+++[ZN197_HUMAN|diamond]RecName: Full=Zinc finger protein 197; AltName: Full=Zinc finger protein with KRAB and SCAN domains 9; AltName: Full=ZnF20; AltName: Full=pVHL-associated KRAB domain-containing protein;+++[ZN445_HUMAN|diamond]RecName: Full=Zinc finger protein 445; AltName: Full=Zinc finger protein 168; AltName: Full=Zinc finger protein with KRAB and SCAN domains 15;+++[ZNF3_HUMAN|diamond]RecName: Full=Zinc finger protein 3; AltName: Full=Zinc finger protein HF.12; AltName: Full=Zinc finger protein HZF3.1; AltName: Full=Zinc finger protein KOX25;"]
[101928635,"'LOC101928635'",7,1,4,"01100///Metabolic pathways+++04979///Cholesterol metabolism+++04137///Mitophagy - animal+++04140///Autophagy - animal+++00561///Glycerolipid metabolism+++04976///Bile secretion",null,"M00098///Acylglycerol degradation","R02250///triacylglycerol acylhydrolase Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase 1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid","GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016323///basolateral plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0034364///high-density lipoprotein particle+++GO:0016021///integral component of membrane","GO:0004806///triglyceride lipase activity+++GO:0004620///phospholipase activity+++GO:0030169///low-density lipoprotein particle binding+++GO:0005345///purine nucleobase transmembrane transporter activity+++GO:0015288///porin activity+++GO:0046872///metal ion binding+++GO:0005372///water transmembrane transporter activity+++GO:0004170///dUTP diphosphatase activity+++GO:0046943///carboxylic acid transmembrane transporter activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0000287///magnesium ion binding+++GO:0015265///urea channel activity+++GO:0003677///DNA binding+++GO:0034185///apolipoprotein binding+++GO:0005350///pyrimidine nucleobase transmembrane transporter activity+++GO:0015166///polyol transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0008201///heparin binding+++GO:0051213///dioxygenase activity+++GO:0005275///amine transmembrane transporter activity+++GO:0015254///glycerol channel activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0015837///amine transport+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0006633///fatty acid biosynthetic process+++GO:0007588///excretion+++GO:0046942///carboxylic acid transport+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0034382///chylomicron remnant clearance+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006226///dUMP biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0015791///polyol transport+++GO:0006863///purine nucleobase transport+++GO:0034373///intermediate-density lipoprotein particle remodeling+++GO:0070328///triglyceride homeostasis+++GO:0010468///regulation of gene expression+++GO:0006955///immune response+++GO:0032197///transposition, RNA-mediated+++GO:0010033///response to organic substance+++GO:0006970///response to osmotic stress+++GO:0015855///pyrimidine nucleobase transport+++GO:0030104///water homeostasis+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0046689///response to mercury ion+++GO:0034638///phosphatidylcholine catabolic process+++GO:0042632///cholesterol homeostasis+++GO:0019433///triglyceride catabolic process+++GO:0071320///cellular response to cAMP+++GO:0015793///glycerol transport+++GO:0034375///high-density lipoprotein particle remodeling+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0015722///canalicular bile acid transport+++GO:0046081///dUTP catabolic process+++GO:0006833///water transport+++GO:0043691///reverse cholesterol transport+++GO:0006310///DNA recombination","IPR016272///Lipase, LIPH-type+++IPR002333///Hepatic lipase+++IPR036392///PLAT/LH2 domain superfamily+++IPR019734///Tetratricopeptide repeat+++IPR009057///Homeobox-like domain superfamily+++IPR001024///PLAT/LH2 domain+++IPR005135///Endonuclease/exonuclease/phosphatase+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR000734///Triacylglycerol lipase family+++IPR015685///Aquaporin 9+++IPR013544///Domain of unknown function DUF1725+++IPR019351///Protein of unknown function DUF2039+++IPR022357///Major intrinsic protein, conserved site+++IPR023271///Aquaporin-like+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR004875///DDE superfamily endonuclease domain+++IPR029516///Histone demethylase UTY+++IPR013818///Lipase/vitellogenin+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR036157///dUTPase-like superfamily+++IPR007889///DNA binding HTH domain, Psq-type+++IPR033906///Lipase, N-terminal+++IPR029054///dUTPase-like+++IPR000425///Major intrinsic protein+++IPR029058///Alpha/Beta hydrolase fold+++IPR000477///Reverse transcriptase domain+++IPR006600///HTH CenpB-type DNA-binding domain+++IPR008181///Deoxyuridine triphosphate nucleotidohydrolase","[AQP10_MILTA|diamond]RecName: Full=Aquaporin-10 {ECO:0000303|PubMed:23761966}; Short=AQP-10 {ECO:0000303|PubMed:23761966};+++[AQP3_MOUSE|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=Aquaglyceroporin-3;+++[AQP3_RAT|diamond]RecName: Full=Aquaporin-3; Short=AQP-3; AltName: Full=31.4 kDa water channel protein; AltName: Full=Aquaglyceroporin-3;+++[AQP9_HUMAN|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9; AltName: Full=Small solute channel 1;+++[AQP9_MOUSE|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[AQP9_RAT|diamond]RecName: Full=Aquaporin-9; Short=AQP-9; AltName: Full=Aquaglyceroporin-9;+++[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DUT_HUMAN|diamond]RecName: Full=Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial; Short=dUTPase; EC=3.6.1.23; AltName: Full=dUTP pyrophosphatase; Flags: Precursor;+++[DUTL_HUMAN|diamond]RecName: Full=Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323; Short=dUTPase-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LIPC_BOVIN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_HUMAN|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_MOUSE|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RABIT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LIPC_RAT|diamond]RecName: Full=Hepatic triacylglycerol lipase; Short=HL; Short=Hepatic lipase; EC=3.1.1.3; AltName: Full=Lipase member C; Flags: Precursor;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYL10_HUMAN|diamond]RecName: Full=Myosin regulatory light chain 10; AltName: Full=Myosin light chain 2, lymphocyte-specific; AltName: Full=Precursor lymphocyte-specific regulatory light chain;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928764,"'LOC101928764'",3,1,2,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005604///basement membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:0007154///cell communication+++GO:0048839///inner ear development+++GO:0001654///eye development+++GO:0042733///embryonic digit morphogenesis+++GO:0007507///heart development+++GO:0002009///morphogenesis of an epithelium","IPR038081///CalX-like domain superfamily+++IPR039005///CSPG repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR003644///Na-Ca exchanger/integrin-beta4+++IPR002110///Ankyrin repeat+++IPR020683///Ankyrin repeat-containing domain","[FREM2_HUMAN|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; Flags: Precursor;+++[FREM2_MOUSE|diamond]RecName: Full=FRAS1-related extracellular matrix protein 2; AltName: Full=ECM3 homolog; AltName: Full=NV domain-containing protein 1; Flags: Precursor;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[POTB2_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B2;+++[POTB3_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B3 {ECO:0000312|HGNC:HGNC:51240};+++[POTEA_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member A; AltName: Full=ANKRD26-like family A member 1; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 8; Short=POTE-8;+++[POTEB_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member B {ECO:0000305}; AltName: Full=ANKRD26-like family B member 1 {ECO:0000305}; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 15 {ECO:0000303|PubMed:15276201}; Short=POTE-15 {ECO:0000303|PubMed:15276201};+++[POTEC_HUMAN|diamond]RecName: Full=POTE ankyrin domain family member C; AltName: Full=ANKRD26-like family B member 2; AltName: Full=Prostate, ovary, testis-expressed protein on chromosome 18; Short=POTE-18;"]
[101928841,"'LOC101928841'",25.97,41.45,33.71,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[FIBH_BOMMO|diamond]RecName: Full=Fibroin heavy chain; Short=Fib-H; AltName: Full=H-fibroin; Flags: Precursor;+++[PHXR5_MOUSE|diamond]RecName: Full=Putative per-hexamer repeat protein 5;+++[TPRX1_HUMAN|diamond]RecName: Full=Tetra-peptide repeat homeobox protein 1;+++[TSEP_GLOPP|diamond]RecName: Full=Protein TsetseEP; AltName: Full=EP-repeat protein; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101928991,"'CCDC92B'",15.14,15.06,15.1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity",null,"IPR031751///Protein of unknown function DUF4735","[CCD92_HUMAN|diamond]RecName: Full=Coiled-coil domain-containing protein 92; AltName: Full=Limkain beta-2;+++[CCD92_MOUSE|diamond]RecName: Full=Coiled-coil domain-containing protein 92;+++[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929097,"'101929097'",58.42,58.54,58.48,{"$nulls":8},"[H2NWX9_PONAB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPPYP00000010497};+++[Q9H7L4_HUMAN|diamond]SubName: Full=FLJ00058 protein {ECO:0000313|EMBL:BAB15755.1}; Flags: Fragment;"]
[101929322,"'LOC101929322'",42,72,57,{"$nulls":4},"GO:0005829///cytosol+++GO:0032587///ruffle membrane+++GO:0005634///nucleus+++GO:0032039///integrator complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0016020///membrane","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding","GO:0043410///positive regulation of MAPK cascade+++GO:0000165///MAPK cascade+++GO:0016180///snRNA processing+++GO:0019933///cAMP-mediated signaling+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0006468///protein phosphorylation","IPR011009///Protein kinase-like domain superfamily+++IPR011989///Armadillo-like helical+++IPR000719///Protein kinase domain+++IPR026003///HEAT repeat associated with sister chromatid cohesion protein+++IPR008271///Serine/threonine-protein kinase, active site+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR025561///Kinase suppressor of RAS, SAM-like domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR016024///Armadillo-type fold","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[INT4_DICDI|diamond]RecName: Full=Integrator complex subunit 4 homolog;+++[INT4_DROME|diamond]RecName: Full=Integrator complex subunit 4 {ECO:0000303|PubMed:21078872};+++[INT4_HUMAN|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_MOUSE|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[INT4_XENLA|diamond]RecName: Full=Integrator complex subunit 4; Short=Int4;+++[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929400,"'LOC101929400'",1.03,0,0.515,{"$nulls":5},"GO:0003723///RNA binding",null,"IPR000504///RNA recognition motif domain+++IPR025670///Fox-1 C-terminal domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR035979///RNA-binding domain superfamily+++IPR034237///FOX1, RNA recognition motif","[A0A2I2ZER1_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000045561};+++[A0A2I3HCP8_NOMLE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000041428};+++[A0A2I3T7A9_PANTR|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNI44179.1}; SubName: Full=RNA binding fox-1 homolog 1 {ECO:0000313|Ensembl:ENSPTRP00000085111};+++[A0A2J8SEY9_PONAB|diamond]SubName: Full=RBFOX1 isoform 7 {ECO:0000313|EMBL:PNJ19325.1};+++[A0A2J8SEZ1_PONAB|diamond]SubName: Full=RBFOX1 isoform 24 {ECO:0000313|EMBL:PNJ19336.1};"]
[101929479,"'LOC101929479'",252.26,421.69,336.975,{"$nulls":4},"GO:0043202///lysosomal lumen+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0032580///Golgi cisterna membrane+++GO:0005796///Golgi lumen+++GO:0031258///lamellipodium membrane+++GO:0000922///spindle pole+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0000137///Golgi cis cisterna+++GO:0000139///Golgi membrane+++GO:0016324///apical plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0072686///mitotic spindle","GO:0045296///cadherin binding+++GO:0061676///importin-alpha family protein binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0019905///syntaxin binding+++GO:0019901///protein kinase binding","GO:0007020///microtubule nucleation+++GO:0060050///positive regulation of protein glycosylation+++GO:0001525///angiogenesis+++GO:0006486///protein glycosylation+++GO:0051289///protein homotetramerization+++GO:0051225///spindle assembly+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0010507///negative regulation of autophagy+++GO:0090307///mitotic spindle assembly+++GO:0000187///activation of MAPK activity+++GO:0030207///chondroitin sulfate catabolic process+++GO:0048771///tissue remodeling+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0090161///Golgi ribbon formation+++GO:0090166///Golgi disassembly+++GO:0090306///spindle assembly involved in meiosis+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0032091///negative regulation of protein binding+++GO:0008356///asymmetric cell division+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0008283///cell proliferation+++GO:0007098///centrosome cycle+++GO:0035556///intracellular signal transduction+++GO:0008347///glial cell migration","IPR039005///CSPG repeat+++IPR024858///Golgin subfamily A+++IPR001791///Laminin G domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily","[CSPG4_HUMAN|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Melanoma chondroitin sulfate proteoglycan; AltName: Full=Melanoma-associated chondroitin sulfate proteoglycan; Flags: Precursor;+++[CSPG4_MOUSE|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=Proteoglycan AN2; Flags: Precursor;+++[CSPG4_RAT|diamond]RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=HSN tumor-specific antigen; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[DYN1_BOVIN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_HUMAN|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_MOUSE|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5;+++[DYN1_RAT|diamond]RecName: Full=Dynamin-1; EC=3.6.5.5; AltName: Full=B-dynamin; AltName: Full=D100; AltName: Full=Dynamin, brain;+++[GGA2B_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 2B; AltName: Full=Golgin subfamily A member 2-like protein 1;+++[GOG6A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6A; AltName: Full=Golgin linked to PML; AltName: Full=Golgin-like protein;+++[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8A; AltName: Full=88 kDa Golgi matrix protein; Short=GM88; AltName: Full=GM88 autoantigen;+++[GOG8B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8B; AltName: Full=Golgin-67;+++[GOG8C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8C;+++[GOG8D_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL5_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon opus; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POLY_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon gypsy; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;"]
[101929627,"'LOC101929627'",0,0.5,0.25,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004527///exonuclease activity+++GO:0003676///nucleic acid binding",null,"IPR034922///RNA exonuclease 1-like, exonuclease domain+++IPR036397///Ribonuclease H superfamily+++IPR013520///Exonuclease, RNase T/DNA polymerase III+++IPR012337///Ribonuclease H-like superfamily+++IPR031736///Elongin A binding-protein 1","[GOR_HUMAN|diamond]RecName: Full=Putative exonuclease GOR; EC=3.1.-.-; AltName: Full=Antigen GOR homolog; AltName: Full=RNA exonuclease 1 homolog-like 1;+++[GOR_PANTR|diamond]RecName: Full=Exonuclease GOR; EC=3.1.-.-; AltName: Full=Antigen GOR; AltName: Full=RNA exonuclease 1 homolog-like;+++[PQE1_CAEEL|diamond]RecName: Full=Putative RNA exonuclease pqe-1; AltName: Full=PolyQ enhancer protein 1;+++[REXO1_HUMAN|diamond]RecName: Full=RNA exonuclease 1 homolog; EC=3.1.-.-; AltName: Full=Elongin-A-binding protein 1; Short=EloA-BP1; AltName: Full=Transcription elongation factor B polypeptide 3-binding protein 1;+++[REXO1_MOUSE|diamond]RecName: Full=RNA exonuclease 1 homolog; EC=3.1.-.-; AltName: Full=Transcription elongation factor B polypeptide 3-binding protein 1;"]
[101929692,"'LOC101929692'",0,3,1.5]
[101929747,"'101929747'",11,5.03,8.015,{"$nulls":8},"[A0A2Y9JJD1_ENHLU|diamond]SubName: Full=uncharacterized protein LOC111148452 {ECO:0000313|RefSeq:XP_022360711.1};"]
[101929796,"'NOTCH2NLR'",35.13,33.76,34.445,"04330///Notch signaling pathway+++01522///Endocrine resistance+++04658///Th1 and Th2 cell differentiation+++05224///Breast cancer+++04919///Thyroid hormone signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05206///MicroRNAs in cancer+++04320///Dorso-ventral axis formation","H00623///Hajdu-Cheney syndrome+++H00409///Type II diabetes mellitus+++H00551///Alagille syndrome","M00682///Notch signaling",null,"GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0005654///nucleoplasm+++GO:0043235///receptor complex+++GO:0005886///plasma membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005576///extracellular region","GO:0038023///signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007399///nervous system development+++GO:0007219///Notch signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006915///apoptotic process+++GO:0002315///marginal zone B cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007050///cell cycle arrest+++GO:0003184///pulmonary valve morphogenesis+++GO:0046849///bone remodeling+++GO:2001204///regulation of osteoclast development+++GO:0030097///hemopoiesis+++GO:0060413///atrial septum morphogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0001709///cell fate determination+++GO:0045967///negative regulation of growth rate+++GO:0009887///animal organ morphogenesis+++GO:0046579///positive regulation of Ras protein signal transduction+++GO:0061314///Notch signaling involved in heart development+++GO:0019827///stem cell population maintenance+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","IPR001881///EGF-like calcium-binding domain+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR000742///EGF-like domain+++IPR008297///Notch+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR018097///EGF-like calcium-binding, conserved site+++IPR011656///Notch, NODP domain+++IPR000800///Notch domain+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR002110///Ankyrin repeat+++IPR022336///Neurogenic locus Notch 2+++IPR035993///Notch-like domain superfamily+++IPR013032///EGF-like, conserved site+++IPR024600///Domain of unknown function DUF3454, notch+++IPR020683///Ankyrin repeat-containing domain+++IPR010660///Notch, NOD domain","[NOTC2_HUMAN|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Short=hN2; Contains: RecName: Full=Notch 2 extracellular truncation; Short=N2ECD {ECO:0000303|PubMed:25985737}; Contains: RecName: Full=Notch 2 intracellular domain; Short=N2ICD {ECO:0000303|PubMed:25985737}; Flags: Precursor;+++[NOTC2_RAT|diamond]RecName: Full=Neurogenic locus notch homolog protein 2; Short=Notch 2; Contains: RecName: Full=Notch 2 extracellular truncation; Contains: RecName: Full=Notch 2 intracellular domain; Flags: Precursor;+++[NT2NA_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein A {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; AltName: Full=Notch homolog 2 N-terminal-like protein {ECO:0000303|PubMed:14673143};+++[NT2NB_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein B {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955}; Flags: Precursor;+++[NT2NC_HUMAN|diamond]RecName: Full=Notch homolog 2 N-terminal-like protein C {ECO:0000303|PubMed:29856954, ECO:0000303|PubMed:29856955};"]
[101929805,"'LOC101929805'",3,0,1.5,{"$nulls":4},"GO:0030016///myofibril+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0034622///cellular protein-containing complex assembly+++GO:0030953///astral microtubule organization+++GO:0090063///positive regulation of microtubule nucleation+++GO:1903358///regulation of Golgi organization","IPR012943///Centrosomin, N-terminal motif 1+++IPR010630///Neuroblastoma breakpoint family (NBPF) domain","[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;"]
[101929895,"'LOC101929895'",1,7,4,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0043209///myelin sheath+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0008017///microtubule binding+++GO:0015631///tubulin binding","GO:0031334///positive regulation of protein complex assembly+++GO:0001578///microtubule bundle formation+++GO:0046785///microtubule polymerization+++GO:0032273///positive regulation of protein polymerization","IPR011992///EF-hand domain pair+++IPR030792///Tubulin polymerisation-promoting protein family member 1+++IPR008907///P25-alpha","[TPPP_BOVIN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=p25-alpha;+++[TPPP_HUMAN|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP; AltName: Full=25 kDa brain-specific protein; AltName: Full=TPPP/p25; AltName: Full=p24; AltName: Full=p25-alpha;+++[TPPP_MOUSE|diamond]RecName: Full=Tubulin polymerization-promoting protein; Short=TPPP;"]
[101929937,"'LOC101929937'",4,2,3,null,"H00773///Autosomal dominant mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0032993///protein-DNA complex+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body+++GO:0030133///transport vesicle","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0021510///spinal cord development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045165///cell fate commitment+++GO:0065004///protein-DNA complex assembly","IPR031267///Transcription factor SOX-12+++IPR017386///Transcription factor SOX-11/4+++IPR029701///Neurensin-2+++IPR036910///High mobility group box domain superfamily+++IPR024883///Neurensin+++IPR009071///High mobility group box domain","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[NRSN2_HUMAN|diamond]RecName: Full=Neurensin-2;+++[NRSN2_MOUSE|diamond]RecName: Full=Neurensin-2;+++[SOX11_CHICK|diamond]RecName: Full=Transcription factor SOX-11; Short=cSox11;+++[SOX11_XENTR|diamond]RecName: Full=Transcription factor Sox-11;+++[SOX12_HUMAN|diamond]RecName: Full=Transcription factor SOX-12; AltName: Full=Protein SOX-22;+++[SOX12_MOUSE|diamond]RecName: Full=Transcription factor SOX-12;+++[SX11B_XENLA|diamond]RecName: Full=Transcription factor Sox-11-B; AltName: Full=Transcription factor Sox-13; Short=xSox-13; AltName: Full=XLS13B;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[101929950,"'LOC101929950'",5.59,18.85,12.22,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0070006///metalloaminopeptidase activity+++GO:0042277///peptide binding","GO:0006508///proteolysis+++GO:0043171///peptide catabolic process","IPR034016///Aminopeptidase N-type+++IPR014782///Peptidase M1, membrane alanine aminopeptidase, N-terminal+++IPR001930///Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase","[ERAP1_MOUSE|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 1; EC=3.4.11.-; AltName: Full=ARTS-1; AltName: Full=Adipocyte-derived leucine aminopeptidase; Short=A-LAP; AltName: Full=Aminopeptidase PILS; AltName: Full=Puromycin-insensitive leucyl-specific aminopeptidase; Short=PILS-AP; AltName: Full=VEGF-induced aminopeptidase;+++[ERAP2_BOVIN|diamond]RecName: Full=Endoplasmic reticulum aminopeptidase 2; EC=3.4.11.-;+++[PSA_CAEEL|diamond]RecName: Full=Puromycin-sensitive aminopeptidase {ECO:0000303|PubMed:12930831}; Short=PSA {ECO:0000305}; EC=3.4.11.14 {ECO:0000305|PubMed:12930831}; AltName: Full=Cytosol alanyl aminopeptidase {ECO:0000305}; Short=AAP-S {ECO:0000305};+++[PSA_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;+++[PSAL_HUMAN|diamond]RecName: Full=Puromycin-sensitive aminopeptidase-like protein; EC=3.4.11.-;+++[PSA_MOUSE|diamond]RecName: Full=Puromycin-sensitive aminopeptidase; Short=PSA; EC=3.4.11.14; AltName: Full=Cytosol alanyl aminopeptidase; Short=AAP-S;"]
[101929959,"'LOC101929959'",183.57,174.56,179.065,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++03320///PPAR signaling pathway+++04140///Autophagy - animal+++04923///Regulation of lipolysis in adipocytes","H02106///Genetic obesity+++H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0030686///90S preribosome+++GO:0005730///nucleolus","GO:0005524///ATP binding+++GO:0005525///GTP binding+++GO:0003723///RNA binding+++GO:0035252///UDP-xylosyltransferase activity+++GO:0034511///U3 snoRNA binding+++GO:0015267///channel activity+++GO:0003924///GTPase activity","GO:0006364///rRNA processing+++GO:0000479///endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0016266///O-glycan processing","IPR019351///Protein of unknown function DUF2039+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR012948///AARP2CN+++IPR037875///Ribosome biogenesis protein Bms1, N-terminal+++IPR002495///Glycosyl transferase, family 8+++IPR007034///Ribosome biogenesis protein BMS1/TSR1, C-terminal+++IPR000425///Major intrinsic protein+++IPR029044///Nucleotide-diphospho-sugar transferases+++IPR030387///Bms1/Tsr1-type G domain+++IPR015686///Aquaporin 7+++IPR023271///Aquaporin-like","[AQP73_HUMAN|diamond]RecName: Full=Putative aquaporin-7-like protein 3;+++[AQP7_HUMAN|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7; AltName: Full=Aquaporin adipose; Short=AQPap; AltName: Full=Aquaporin-7-like;+++[AQP7_MACFA|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[AQP7_MOUSE|diamond]RecName: Full=Aquaporin-7; Short=AQP-7; AltName: Full=Aquaglyceroporin-7;+++[BMS1_HUMAN|diamond]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GXLT1_HUMAN|diamond]RecName: Full=Glucoside xylosyltransferase 1; EC=2.4.2.n2; AltName: Full=Glycosyltransferase 8 domain-containing protein 3;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[TSR1_DICDI|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_HUMAN|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_MOUSE|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_PONAB|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[TSR1_XENLA|diamond]RecName: Full=Pre-rRNA-processing protein TSR1 homolog;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10193,"'RNF41'",1012.14,929.45,970.795,"04144///Endocytosis",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0071782///endoplasmic reticulum tubular network","GO:0004842///ubiquitin-protein transferase activity+++GO:0019904///protein domain specific binding+++GO:0017160///Ral GTPase binding+++GO:0005128///erythropoietin receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0005135///interleukin-3 receptor binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity","GO:0010498///proteasomal protein catabolic process+++GO:0051896///regulation of protein kinase B signaling+++GO:0051865///protein autoubiquitination+++GO:0006915///apoptotic process+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:2000114///regulation of establishment of cell polarity+++GO:0006914///autophagy+++GO:0045637///regulation of myeloid cell differentiation+++GO:0030336///negative regulation of cell migration+++GO:0010468///regulation of gene expression+++GO:1901525///negative regulation of mitophagy+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0045619///regulation of lymphocyte differentiation+++GO:0000209///protein polyubiquitination+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0008285///negative regulation of cell proliferation+++GO:0043408///regulation of MAPK cascade+++GO:0016567///protein ubiquitination","IPR017907///Zinc finger, RING-type, conserved site+++IPR015036///E3 ubiquitin-protein ligase NRDP1+++IPR008974///TRAF-like+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR013010///Zinc finger, SIAH-type+++IPR037255///NRDP1, C-terminal","[RNF41_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase NRDP1; EC=2.3.2.27; AltName: Full=RING finger protein 41; AltName: Full=RING-type E3 ubiquitin transferase NRDP1 {ECO:0000305};+++[A0A024RB33_HUMAN|Unreviewed]SubName: Full=Ring finger protein 41, isoform CRA_b {ECO:0000313|EMBL:EAW96911.1};+++[F8VNZ6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000450164}; Flags: Fragment;+++[F8VSB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448187};+++[F8VSE5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000448330};+++[F8VSP7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000446595}; Flags: Fragment;+++[F8VVY2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase NRDP1 {ECO:0000313|Ensembl:ENSP00000449575};"]
[101930047,"'LOC101930047'",0,2,1,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:0032587///ruffle membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0008022///protein C-terminus binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0005524///ATP binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0071889///14-3-3 protein binding","GO:0043405///regulation of MAP kinase activity+++GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0007265///Ras protein signal transduction+++GO:0043410///positive regulation of MAPK cascade+++GO:0019933///cAMP-mediated signaling","IPR025561///Kinase suppressor of RAS, SAM-like domain+++IPR011009///Protein kinase-like domain superfamily+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR000719///Protein kinase domain","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;+++[KSR2_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 2; Short=hKSR2; EC=2.7.11.1;+++[KSR2_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 2; EC=2.7.11.1;"]
[101930307,"'LOC101930307'",29,46,37.5,{"$nulls":4},"GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity","GO:0008152///metabolic process","IPR019351///Protein of unknown function DUF2039","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[10194,"'TSHZ1'",59,77,68,"04391///Hippo signaling pathway - fly","H02115///Congenital aural atresia",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0009952///anterior/posterior pattern specification+++GO:0007275///multicellular organism development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010468///regulation of gene expression+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060023///soft palate development+++GO:0042474///middle ear morphogenesis","IPR027008///Teashirt family+++IPR026808///Teashirt  homologue 1+++IPR013087///Zinc finger C2H2-type+++IPR001356///Homeobox domain","[TSH1_HUMAN|Reviewed]RecName: Full=Teashirt homolog 1; AltName: Full=Antigen NY-CO-33; AltName: Full=Serologically defined colon cancer antigen 33;+++[A7YF73_HUMAN|Unreviewed]SubName: Full=TSHZ1 protein {ECO:0000313|EMBL:AAH24152.2}; Flags: Fragment;+++[H0YKA1_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000452718}; Flags: Fragment;+++[H0YN23_HUMAN|Unreviewed]SubName: Full=Teashirt homolog 1 {ECO:0000313|Ensembl:ENSP00000453834}; Flags: Fragment;"]
[10195,"'ALG3'",2547,2259,2403,"00513///Various types of N-glycan biosynthesis+++00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R06258///Dolichyl phosphate D-mannose + G00006 <=> Dolichyl phosphate + G10595","GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0005515///protein binding+++GO:0052925///dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0000030///mannosyltransferase activity+++GO:0000033///alpha-1,3-mannosyltransferase activity","GO:0006488///dolichol-linked oligosaccharide biosynthetic process+++GO:0006486///protein glycosylation+++GO:0097502///mannosylation","IPR007873///Glycosyltransferase, ALG3","[ALG3_HUMAN|Reviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; EC=2.4.1.258; AltName: Full=Asparagine-linked glycosylation protein 3 homolog; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase; AltName: Full=Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase; AltName: Full=Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase; AltName: Full=Not56-like protein;+++[C9J7S5_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047};+++[F8WE30_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000394917};+++[F8WF93_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000407011};+++[H7BZZ2_HUMAN|Unreviewed]SubName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000313|Ensembl:ENSP00000392209}; Flags: Fragment;+++[H7C0X4_HUMAN|Unreviewed]RecName: Full=Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; EC=2.4.1.258 {ECO:0000256|RuleBase:RU364047}; AltName: Full=Dol-P-Man-dependent alpha(1-3)-mannosyltransferase {ECO:0000256|RuleBase:RU364047}; Flags: Fragment;"]
[10196,"'PRMT3'",58,52,55,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,null,"R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine","GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol","GO:0008168///methyltransferase activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0043022///ribosome binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0034969///histone arginine methylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0031397///negative regulation of protein ubiquitination+++GO:0032259///methylation+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006479///protein methylation","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR025799///Protein arginine N-methyltransferase+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[ANM3_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 3; EC=2.1.1.-; AltName: Full=Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3;+++[E9PLF6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000435151};+++[E9PRB4_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|Ensembl:ENSP00000434260};+++[Q8WUV3_HUMAN|Unreviewed]SubName: Full=PRMT3 protein {ECO:0000313|EMBL:AAH19339.1}; Flags: Fragment;"]
[10197,"'PSME3'",2309,2419,2364,"03050///Proteasome+++05160///Hepatitis C+++04612///Antigen processing and presentation",null,null,"R03139///primary-amine oxidase 1,3-Diaminopropane + Oxygen + H2O <=> 3-Aminopropanal + Ammonia + Hydrogen peroxide+++R06740///primary-amine oxidase Cadaverine + H2O + Oxygen <=> 5-Aminopentanal + Ammonia + Hydrogen peroxide+++R02613///Phenethylamine:oxygen oxidoreductase (deaminating) Phenethylamine + Oxygen + H2O <=> Phenylacetaldehyde + Ammonia + Hydrogen peroxide+++R06154///methylamine:oxygen oxidoreductase (deaminating) (copper-containing) Methylamine + Oxygen + H2O <=> Formaldehyde + Ammonia + Hydrogen peroxide+++R02529///aminoacetone:oxygen oxidoreductase(deaminating) Aminoacetone + H2O + Oxygen <=> Methylglyoxal + Ammonia + Hydrogen peroxide+++R02382///Tyramine:oxygen oxidoreductase(deaminating)(flavin-containing) Tyramine + H2O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04300///4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing) Dopamine + H2O + Oxygen <=> 3,4-Dihydroxyphenylacetaldehyde + Ammonia + Hydrogen peroxide+++R04027///primary-amine oxidase N-Methylputrescine + Oxygen + H+ <=> 1-Methylpyrrolinium + Hydrogen peroxide + Ammonia","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0008537///proteasome activator complex+++GO:0000502///proteasome complex","GO:0061133///endopeptidase activator activity+++GO:0002039///p53 binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007049///cell cycle+++GO:0043687///post-translational protein modification+++GO:0010950///positive regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0006915///apoptotic process","IPR036997///Proteasome activator PA28, C-terminal domain superfamily+++IPR036996///Proteasome activator PA28, N-terminal domain superfamily+++IPR003185///Proteasome activator PA28, N-terminal domain+++IPR003186///Proteasome activator PA28, C-terminal domain+++IPR036252///Proteasome activator superfamily+++IPR009077///Proteasome activator PA28","[PSME3_HUMAN|Reviewed]RecName: Full=Proteasome activator complex subunit 3; AltName: Full=11S regulator complex subunit gamma; Short=REG-gamma; AltName: Full=Activator of multicatalytic protease subunit 3; AltName: Full=Ki nuclear autoantigen; AltName: Full=Proteasome activator 28 subunit gamma; Short=PA28g; Short=PA28gamma;+++[A0A024R203_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) activator subunit 3 (PA28 gamma Ki), isoform CRA_a {ECO:0000313|EMBL:EAW60894.1};+++[A0A087WTV2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000478159};+++[B3KQ25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32659 fis, clone TESTI1000045, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAG51887.1};+++[B7Z8D3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57249, highly similar to Proteasome activator complex subunit 3 {ECO:0000313|EMBL:BAH13919.1};+++[K7EJF8_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465155};+++[K7EKR3_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000465743}; Flags: Fragment;+++[K7EMD0_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466451}; Flags: Fragment;+++[K7ENH2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000466945}; Flags: Fragment;+++[K7EPX6_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000467580}; Flags: Fragment;+++[K7ESG5_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000468702};+++[K9J957_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 3 {ECO:0000313|Ensembl:ENSP00000438237}; SubName: Full=REG gamma-3 variant {ECO:0000313|EMBL:ACO54885.1};+++[Q6FHK7_HUMAN|Unreviewed]SubName: Full=PSME3 protein {ECO:0000313|EMBL:CAG46545.1};+++[Q6MZZ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686J2076 {ECO:0000313|EMBL:CAE45884.1};+++[V9HWJ8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 283 {ECO:0000313|EMBL:ACJ13707.1};"]
[10198,"'MPHOSPH9'",79,154,116.5,{"$nulls":4},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005794///Golgi apparatus",null,null,"IPR026636///M-phase phosphoprotein 9","[MPP9_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 9;+++[A0A0A0MTP3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000445859};+++[F5GYG6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440664}; Flags: Fragment;+++[F5GYP5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441298}; Flags: Fragment;+++[F5H1U6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446362}; Flags: Fragment;+++[F5H1W2_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446334}; Flags: Fragment;+++[F5H2I5_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000446249};+++[F5H798_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000442663};+++[H0YFS3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000440007}; Flags: Fragment;+++[H0YG46_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000441764}; Flags: Fragment;+++[J3KNE4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000304096}; Flags: Fragment;+++[U3KQ61_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475578}; Flags: Fragment;+++[U3KQD6_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475785}; Flags: Fragment;+++[U3KQJ0_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 9 {ECO:0000313|Ensembl:ENSP00000475923}; Flags: Fragment;"]
[10199,"'MPHOSPH10'",278,297,287.5,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034457///Mpp10 complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006396///RNA processing+++GO:0042254///ribosome biogenesis+++GO:0010923///negative regulation of phosphatase activity+++GO:0006364///rRNA processing+++GO:0008380///RNA splicing","IPR012173///U3 small nucleolar ribonucleoprotein complex, subunit Mpp10","[MPP10_HUMAN|Reviewed]RecName: Full=U3 small nucleolar ribonucleoprotein protein MPP10; AltName: Full=M phase phosphoprotein 10;+++[U3KQ48_HUMAN|Unreviewed]SubName: Full=U3 small nucleolar ribonucleoprotein protein MPP10 {ECO:0000313|Ensembl:ENSP00000475545};"]
[102,"'ADAM10'",1512,2086,1799,"05010///Alzheimer's disease+++05120///Epithelial cell signaling in Helicobacter pylori infection",{"$nulls":3},"GO:0043197///dendritic spine+++GO:0030425///dendrite+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0043025///neuronal cell body+++GO:0070062///extracellular exosome+++GO:0070821///tertiary granule membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0098794///postsynapse+++GO:0005798///Golgi-associated vesicle+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0005802///trans-Golgi network+++GO:0016021///integral component of membrane+++GO:0035579///specific granule membrane+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion","GO:0004222///metalloendopeptidase activity+++GO:0019901///protein kinase binding+++GO:0008233///peptidase activity+++GO:0005102///signaling receptor binding+++GO:0005178///integrin binding+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0017124///SH3 domain binding+++GO:0008237///metallopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0008284///positive regulation of cell proliferation+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0034205///amyloid-beta formation+++GO:0030307///positive regulation of cell growth+++GO:0001701///in utero embryonic development+++GO:0007162///negative regulation of cell adhesion+++GO:0043687///post-translational protein modification+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0007219///Notch signaling pathway+++GO:0016485///protein processing+++GO:0051089///constitutive protein ectodomain proteolysis+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0034612///response to tumor necrosis factor+++GO:0007283///spermatogenesis+++GO:0022617///extracellular matrix disassembly+++GO:0051088///PMA-inducible membrane protein ectodomain proteolysis+++GO:0006508///proteolysis+++GO:0007267///cell-cell signaling+++GO:0098696///regulation of neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0007229///integrin-mediated signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0097327///response to antineoplastic agent+++GO:0006468///protein phosphorylation+++GO:0030335///positive regulation of cell migration+++GO:0043312///neutrophil degranulation+++GO:0099173///postsynapse organization+++GO:0042117///monocyte activation+++GO:0035333///Notch receptor processing, ligand-dependent+++GO:0043065///positive regulation of apoptotic process","IPR034025///ADAM10/ADAM17 catalytic domain+++IPR001590///Peptidase M12B, ADAM/reprolysin+++IPR036436///Disintegrin domain superfamily+++IPR002870///Peptidase M12B, propeptide+++IPR001762///Disintegrin domain+++IPR024079///Metallopeptidase, catalytic domain superfamily+++IPR027053///Disintegrin and metalloproteinase domain-containing protein 10","[ADA10_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 10; Short=ADAM 10; EC=3.4.24.81 {ECO:0000269|PubMed:11477090, ECO:0000269|PubMed:12475894, ECO:0000269|PubMed:16239146, ECO:0000269|PubMed:17557115, ECO:0000269|PubMed:19114711, ECO:0000269|PubMed:20592283, ECO:0000269|PubMed:29224781}; AltName: Full=CDw156; AltName: Full=Kuzbanian protein homolog; AltName: Full=Mammalian disintegrin-metalloprotease; AltName: CD_antigen=CD156c; Flags: Precursor;+++[A0A024R5U5_HUMAN|Unreviewed]SubName: Full=ADAM metallopeptidase domain 10, isoform CRA_b {ECO:0000313|EMBL:EAW77541.1};+++[A0A087WYG1_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000481779};+++[A0AV88_HUMAN|Unreviewed]SubName: Full=ADAM10 protein {ECO:0000313|EMBL:AAI26254.1};+++[B5MC71_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000386056};+++[C9J9B4_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000391930}; Flags: Fragment;+++[H0YK32_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452639};+++[H0YK87_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000452704}; Flags: Fragment;+++[H0YNC5_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000453952}; Flags: Fragment;+++[H3BS53_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000456542}; Flags: Fragment;+++[L8E9R5_HUMAN|Unreviewed]SubName: Full=Alternative protein ADAM10 {ECO:0000313|EMBL:CCQ43088.1};"]
[1020,"'CDK5'",508,500,504,"05010///Alzheimer's disease+++05030///Cocaine addiction+++04360///Axon guidance","H00268///Lissencephaly (LIS)",null,null,"GO:0005874///microtubule+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0031594///neuromuscular junction+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0043204///perikaryon+++GO:0030027///lamellipodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0098794///postsynapse+++GO:0030424///axon+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane+++GO:0016533///protein kinase 5 complex+++GO:0030425///dendrite+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0045202///synapse","GO:0016301///kinase activity+++GO:0043125///ErbB-3 class receptor binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0002039///p53 binding+++GO:0050321///tau-protein kinase activity+++GO:0000166///nucleotide binding+++GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels+++GO:0051879///Hsp90 protein binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0048156///tau protein binding+++GO:0046875///ephrin receptor binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0030549///acetylcholine receptor activator activity+++GO:0005176///ErbB-2 class receptor binding+++GO:0008017///microtubule binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008092///cytoskeletal protein binding+++GO:0016740///transferase activity","GO:0007399///nervous system development+++GO:0051402///neuron apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0008542///visual learning+++GO:0030866///cortical actin cytoskeleton organization+++GO:0030334///regulation of cell migration+++GO:0032801///receptor catabolic process+++GO:0000226///microtubule cytoskeleton organization+++GO:0045861///negative regulation of proteolysis+++GO:0098883///synapse pruning+++GO:0032092///positive regulation of protein binding+++GO:0008306///associative learning+++GO:2000273///positive regulation of signaling receptor activity+++GO:0048813///dendrite morphogenesis+++GO:0071156///regulation of cell cycle arrest+++GO:0022038///corpus callosum development+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0008045///motor neuron axon guidance+++GO:0016079///synaptic vesicle exocytosis+++GO:0042220///response to cocaine+++GO:0008283///cell proliferation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0009611///response to wounding+++GO:0048489///synaptic vesicle transport+++GO:0070509///calcium ion import+++GO:0048812///neuron projection morphogenesis+++GO:0021695///cerebellar cortex development+++GO:0016241///regulation of macroautophagy+++GO:1904646///cellular response to amyloid-beta+++GO:0006886///intracellular protein transport+++GO:0035418///protein localization to synapse+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0021766///hippocampus development+++GO:0045860///positive regulation of protein kinase activity+++GO:0034352///positive regulation of glial cell apoptotic process+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:0031397///negative regulation of protein ubiquitination+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0007049///cell cycle+++GO:0030182///neuron differentiation+++GO:0046826///negative regulation of protein export from nucleus+++GO:0016572///histone phosphorylation+++GO:0030900///forebrain development+++GO:0048167///regulation of synaptic plasticity+++GO:0031175///neuron projection development+++GO:0048148///behavioral response to cocaine+++GO:0035249///synaptic transmission, glutamatergic+++GO:0060079///excitatory postsynaptic potential+++GO:0045055///regulated exocytosis+++GO:0007409///axonogenesis+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0042501///serine phosphorylation of STAT protein+++GO:0006915///apoptotic process+++GO:0051301///cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0019233///sensory perception of pain+++GO:0014044///Schwann cell development+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0021697///cerebellar cortex formation+++GO:0006913///nucleocytoplasmic transport+++GO:0007519///skeletal muscle tissue development+++GO:0007005///mitochondrion organization+++GO:0021537///telencephalon development+++GO:0045786///negative regulation of cell cycle+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0048709///oligodendrocyte differentiation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007160///cell-matrix adhesion+++GO:0021987///cerebral cortex development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006887///exocytosis+++GO:0007268///chemical synaptic transmission+++GO:0021954///central nervous system neuron development+++GO:0021819///layer formation in cerebral cortex+++GO:0048675///axon extension+++GO:0043113///receptor clustering+++GO:0006468///protein phosphorylation+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0001764///neuron migration+++GO:0021549///cerebellum development+++GO:1903421///regulation of synaptic vesicle recycling+++GO:0001963///synaptic transmission, dopaminergic+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0016477///cell migration+++GO:0030517///negative regulation of axon extension+++GO:0048511///rhythmic process+++GO:1901215///negative regulation of neuron death+++GO:1901216///positive regulation of neuron death+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0007416///synapse assembly+++GO:0016310///phosphorylation","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[CDK5_HUMAN|Reviewed]RecName: Full=Cyclin-dependent-like kinase 5; EC=2.7.11.1; AltName: Full=Cell division protein kinase 5; AltName: Full=Serine/threonine-protein kinase PSSALRE; AltName: Full=Tau protein kinase II catalytic subunit; Short=TPKII catalytic subunit;+++[A0A090N7W4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 {ECO:0000313|EMBL:EAL24498.1}; SubName: Full=Cyclin-dependent kinase 5 isoform 1 {ECO:0000313|EMBL:ALQ33426.1}; SubName: Full=Cyclin-dependent kinase 5, isoform CRA_a {ECO:0000313|EMBL:EAW54049.1};+++[A0A0S2Z355_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 5 isoform 2 {ECO:0000313|EMBL:ALQ33427.1}; Flags: Fragment;+++[Q6IAW3_HUMAN|Unreviewed]SubName: Full=CDK5 protein {ECO:0000313|EMBL:CAG33322.1};"]
[10200,"'MPHOSPH6'",121,101,111,"03018///RNA degradation",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0000178///exosome (RNase complex)+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0030165///PDZ domain binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0000460///maturation of 5.8S rRNA+++GO:0065003///protein-containing complex assembly","IPR019324///M-phase phosphoprotein 6","[MPH6_HUMAN|Reviewed]RecName: Full=M-phase phosphoprotein 6 {ECO:0000305};+++[H3BNK8_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6, isoform CRA_b {ECO:0000313|EMBL:EAW95517.1};+++[H3BNT4_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000454996};+++[H3BSB3_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000456626};+++[H3BU96_HUMAN|Unreviewed]SubName: Full=M-phase phosphoprotein 6 {ECO:0000313|Ensembl:ENSP00000457537};"]
[10201,"'NME6'",220.01,233.61,226.81,"04016///MAPK signaling pathway - plant+++00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00230///Purine metabolism",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase   ATP + dCDP <=> ADP + dCTP+++R00124///ATP:ADP phosphatransferase   ATP + ADP <=> ADP + ATP+++R00156///ATP:UDP phosphotransferase   ATP + UDP <=> ADP + UTP+++R00330///ATP:GDP phosphotransferase   ATP + GDP <=> ADP + GTP+++R01857///ATP:dGDP phosphotransferase   ATP + dGDP <=> ADP + dGTP+++R00570///ATP:CDP phosphotransferase   ATP + CDP <=> ADP + CTP+++R11895///ATP:5-fluorodeoxyuridine-diphosphate phosphotransferase   ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate+++R01137///ATP:dADP phosphotransferase   ATP + dADP <=> ADP + dATP+++R02331///ATP:dUDP phosphotransferase   ATP + dUDP <=> ADP + dUTP+++R02093///ATP:dTDP phosphotransferase   ATP + dTDP <=> ADP + dTTP+++R00139///ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase   2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP+++R00722///ATP:IDP phosphotransferase   ATP + IDP <=> ADP + ITP+++R11894///ATP:5-fluorouridine-diphosphate phosphotransferase   ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate+++R03530///ATP:dIDP phosphotransferase   ATP + dIDP <=> ADP + dITP","GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0004550///nucleoside diphosphate kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0045839///negative regulation of mitotic nuclear division+++GO:0016310///phosphorylation+++GO:0006165///nucleoside diphosphate phosphorylation+++GO:0006183///GTP biosynthetic process+++GO:0006241///CTP biosynthetic process+++GO:0009117///nucleotide metabolic process+++GO:0030308///negative regulation of cell growth+++GO:0006228///UTP biosynthetic process+++GO:0006915///apoptotic process","IPR001564///Nucleoside diphosphate kinase+++IPR036850///Nucleoside diphosphate kinase-like domain superfamily+++IPR023005///Nucleoside diphosphate kinase, active site+++IPR037994///Nucleoside diphosphate kinase 6+++IPR034907///Nucleoside diphosphate kinase-like domain","[NDK6_HUMAN|Reviewed]RecName: Full=Nucleoside diphosphate kinase 6; Short=NDK 6; Short=NDP kinase 6; EC=2.7.4.6; AltName: Full=Inhibitor of p53-induced apoptosis-alpha; Short=IPIA-alpha; AltName: Full=nm23-H6;+++[A0A0C4DG91_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y547_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[A0A2R8Y7V2_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[C9J1J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000392715}; Flags: Fragment;+++[C9J867_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000405755}; Flags: Fragment;+++[C9J9V6_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013}; Flags: Fragment;+++[C9JQB1_HUMAN|Unreviewed]RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013}; EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};+++[F2Z2J2_HUMAN|Unreviewed]SubName: Full=Nucleoside diphosphate kinase 6 {ECO:0000313|Ensembl:ENSP00000410435};"]
[10202,"'DHRS2'",46,43,44.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix","GO:0016491///oxidoreductase activity+++GO:0004090///carbonyl reductase (NADPH) activity+++GO:0005515///protein binding","GO:0008285///negative regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0008207///C21-steroid hormone metabolic process+++GO:0009636///response to toxic substance+++GO:0055114///oxidation-reduction process+++GO:0043011///myeloid dendritic cell differentiation+++GO:0034599///cellular response to oxidative stress","IPR027052///Dehydrogenase/reductase SDR member 2+++IPR036291///NAD(P)-binding domain superfamily+++IPR002347///Short-chain dehydrogenase/reductase SDR+++IPR020904///Short-chain dehydrogenase/reductase, conserved site","[DHRS2_HUMAN|Reviewed]RecName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial; EC=1.1.1.-; AltName: Full=Dicarbonyl reductase HEP27; AltName: Full=Protein D; AltName: Full=Short chain dehydrogenase/reductase family 25C member 1; Flags: Precursor;+++[C9JZP6_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000401213}; Flags: Fragment;+++[H0YJG9_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451485}; Flags: Fragment;+++[H0YJP4_HUMAN|Unreviewed]SubName: Full=Dehydrogenase/reductase SDR family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000451895}; Flags: Fragment;"]
[10203,"'CALCRL'",1,0,0.5,"04080///Neuroactive ligand-receptor interaction+++04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:1990406///CGRP receptor complex+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:1903143///adrenomedullin receptor complex","GO:1990409///adrenomedullin binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0004930///G protein-coupled receptor activity+++GO:0001605///adrenomedullin receptor activity+++GO:0004948///calcitonin receptor activity","GO:0045986///negative regulation of smooth muscle contraction+++GO:0007507///heart development+++GO:0001525///angiogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0031623///receptor internalization+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0006816///calcium ion transport+++GO:0015031///protein transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway+++GO:0071329///cellular response to sucrose stimulus+++GO:0050728///negative regulation of inflammatory response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway","IPR003289///GPCR, family 2, calcitonin gene-related peptide, type 1 receptor+++IPR001879///GPCR, family 2, extracellular hormone receptor domain+++IPR017981///GPCR, family 2-like+++IPR000832///GPCR, family 2, secretin-like+++IPR036445///GPCR family 2, extracellular hormone receptor domain superfamily+++IPR017983///GPCR, family 2, secretin-like, conserved site+++IPR003287///GPCR, family 2, calcitonin receptor family","[CALRL_HUMAN|Reviewed]RecName: Full=Calcitonin gene-related peptide type 1 receptor; Short=CGRP type 1 receptor; AltName: Full=Calcitonin receptor-like receptor; Flags: Precursor;+++[B8ZZJ4_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000386599}; Flags: Fragment;+++[D3DPG9_HUMAN|Unreviewed]SubName: Full=Calcitonin receptor-like, isoform CRA_a {ECO:0000313|EMBL:EAX10926.1};+++[E7EN01_HUMAN|Unreviewed]SubName: Full=Calcitonin gene-related peptide type 1 receptor {ECO:0000313|Ensembl:ENSP00000415626}; Flags: Fragment;"]
[10204,"'NUTF2'",3752,3265,3508.5,{"$nulls":4},"GO:0044613///nuclear pore central transport channel+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0005637///nuclear inner membrane+++GO:0005643///nuclear pore+++GO:0005640///nuclear outer membrane","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0017056///structural constituent of nuclear pore","GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0042307///positive regulation of protein import into nucleus+++GO:0090204///protein localization to nuclear pore+++GO:1904046///negative regulation of vascular endothelial growth factor production+++GO:0015031///protein transport+++GO:0000060///protein import into nucleus, translocation+++GO:0006913///nucleocytoplasmic transport","IPR002075///Nuclear transport factor 2+++IPR018222///Nuclear transport factor 2, eukaryote+++IPR032710///NTF2-like domain superfamily","[NTF2_HUMAN|Reviewed]RecName: Full=Nuclear transport factor 2 {ECO:0000303|PubMed:7744965}; Short=NTF-2; AltName: Full=Placental protein 15 {ECO:0000303|PubMed:3380696}; Short=PP15 {ECO:0000303|PubMed:3380696};+++[A0A024R6Y2_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2, isoform CRA_a {ECO:0000313|EMBL:EAW83182.1};+++[H3BRV9_HUMAN|Unreviewed]SubName: Full=Nuclear transport factor 2 {ECO:0000313|Ensembl:ENSP00000456428}; Flags: Fragment;"]
[10206,"'TRIM13'",269.59,243.9,256.745,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0005737///cytoplasm+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding","GO:1902187///negative regulation of viral release from host cell+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0010332///response to gamma radiation+++GO:0016239///positive regulation of macroautophagy+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0002376///immune system process+++GO:0051865///protein autoubiquitination+++GO:0009653///anatomical structure morphogenesis+++GO:0010942///positive regulation of cell death+++GO:0016567///protein ubiquitination+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0045087///innate immune response+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:0032897///negative regulation of viral transcription","IPR000315///B-box-type zinc finger+++IPR017907///Zinc finger, RING-type, conserved site+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR003131///Potassium channel tetramerisation-type BTB domain+++IPR027370///RING-type zinc-finger, LisH dimerisation motif","[TRI13_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM13; EC=2.3.2.27; AltName: Full=B-cell chronic lymphocytic leukemia tumor suppressor Leu5; AltName: Full=Leukemia-associated protein 5; AltName: Full=Putative tumor suppressor RFP2; AltName: Full=RING finger protein 77; AltName: Full=RING-type E3 ubiquitin transferase TRIM13 {ECO:0000305}; AltName: Full=Ret finger protein 2; AltName: Full=Tripartite motif-containing protein 13;+++[A0A024RDU3_HUMAN|Unreviewed]SubName: Full=Ret finger protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX08848.1};+++[A0A184AP76_HUMAN|Unreviewed]SubName: Full=Putative tumor suppressor RFP2 {ECO:0000313|EMBL:ABE41638.1};+++[L7MTJ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAD38633.1}; Flags: Fragment;+++[L8E9D0_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM13 {ECO:0000313|EMBL:CCQ43336.1};+++[X6R9U5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000367425}; Flags: Fragment;+++[X6RH27_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM13 {ECO:0000313|Ensembl:ENSP00000404586}; Flags: Fragment;"]
[10207,"'PATJ'",126,100,113,"04390///Hippo signaling pathway+++05165///Human papillomavirus infection+++04530///Tight junction",{"$nulls":3},"GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0045177///apical part of cell+++GO:0032991///protein-containing complex+++GO:0005923///bicellular tight junction+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding","GO:0035556///intracellular signal transduction+++GO:0070830///bicellular tight junction assembly","IPR036892///L27 domain superfamily+++IPR001478///PDZ domain+++IPR004172///L27 domain+++IPR015132///L27-2+++IPR036034///PDZ superfamily","[INADL_HUMAN|Reviewed]RecName: Full=InaD-like protein; Short=Inadl protein; Short=hINADL; AltName: Full=Pals1-associated tight junction protein; AltName: Full=Protein associated to tight junctions;+++[A0A087WUZ6_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000479041};+++[A0A0U1RQR3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489130}; Flags: Fragment;+++[A0A0U1RQT2_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489159};+++[A0A0U1RQW4_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489200}; Flags: Fragment;+++[A0A0U1RR46_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489335};+++[A0A0U1RRD7_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000489475}; Flags: Fragment;+++[A0A0X1KG69_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000326199};+++[A0A2R8Y549_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494277};+++[A0A2R8Y5I3_HUMAN|Unreviewed]SubName: Full=InaD-like protein {ECO:0000313|Ensembl:ENSP00000494824};+++[A5PKX9_HUMAN|Unreviewed]SubName: Full=INADL protein {ECO:0000313|EMBL:AAI42662.1};+++[B4DE90_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59473, highly similar to InaD-like protein {ECO:0000313|EMBL:BAG57001.1};"]
[10208,"'USPL1'",233,288,260.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0005515///protein binding+++GO:0032183///SUMO binding+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0070140///SUMO-specific isopeptidase activity+++GO:0043130///ubiquitin binding","GO:0030576///Cajal body organization+++GO:0009301///snRNA transcription+++GO:0006508///proteolysis+++GO:0016926///protein desumoylation+++GO:0008283///cell proliferation","IPR029388///Domain of unknown function DUF4650+++IPR028890///Ubiquitin-specific peptidase-like, SUMO isopeptidase+++IPR028889///Ubiquitin specific protease domain+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR033505///USPL1 peptidase","[USPL1_HUMAN|Reviewed]RecName: Full=SUMO-specific isopeptidase USPL1; EC=3.4.22.-; AltName: Full=Ubiquitin-specific peptidase-like protein 1; Short=USP-like 1;+++[A8K1B1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75211, highly similar to Homo sapiens ubiquitin specific peptidase like 1, mRNA {ECO:0000313|EMBL:BAF82515.1};+++[B3KQ64_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32952 fis, clone TESTI2008081, highly similar to Homo sapiens D13S106 a highly charged amino acid sequence {ECO:0000313|EMBL:BAG51926.1}; Flags: Fragment;+++[L8ECC7_HUMAN|Unreviewed]SubName: Full=Alternative protein USPL1 {ECO:0000313|EMBL:CCQ43337.1};"]
[10209,"'EIF1'",3327,2745,3036,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding","GO:0006412///translation+++GO:0006446///regulation of translational initiation+++GO:0009048///dosage compensation by inactivation of X chromosome+++GO:0006413///translational initiation","IPR001950///SUI1 domain+++IPR036877///SUI1 domain superfamily+++IPR005874///Eukaryotic translation initiation factor SUI1","[EIF1_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1; Short=eIF1; AltName: Full=A121; AltName: Full=Protein translation factor SUI1 homolog; AltName: Full=Sui1iso1;+++[K7EM18_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000466321};+++[K7EQP2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1 {ECO:0000313|Ensembl:ENSP00000467918}; Flags: Fragment;+++[Q6IAV3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW60754.1}; SubName: Full=Putative translation initiation factor {ECO:0000313|EMBL:AAP35291.1}; SubName: Full=SUI1 protein {ECO:0000313|EMBL:CAG33332.1}; SubName: Full=cDNA, FLJ92128, Homo sapiens putative translation initiation factor (SUI1), mRNA {ECO:0000313|EMBL:BAG34803.1};"]
[1021,"'CDK6'",2326,3618,2972,"05218///Melanoma+++05224///Breast cancer+++04110///Cell cycle+++05200///Pathways in cancer+++05214///Glioma+++04218///Cellular senescence+++05220///Chronic myeloid leukemia+++05222///Small cell lung cancer+++05162///Measles+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04151///PI3K-Akt signaling pathway+++05223///Non-small cell lung cancer+++05163///Human cytomegalovirus infection+++04934///Cushing's syndrome+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++05161///Hepatitis B+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05165///Human papillomavirus infection+++05212///Pancreatic cancer","H00269///Primary microcephaly (MCPH)","M00692///Cell cycle - G1/S transition",null,"GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0001726///ruffle+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0098770///FBXO family protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0030332///cyclin binding+++GO:0016740///transferase activity","GO:0050680///negative regulation of epithelial cell proliferation+++GO:0043697///cell dedifferentiation+++GO:0007049///cell cycle+++GO:0048699///generation of neurons+++GO:0045668///negative regulation of osteoblast differentiation+++GO:2000145///regulation of cell motility+++GO:0045656///negative regulation of monocyte differentiation+++GO:0014002///astrocyte development+++GO:0003323///type B pancreatic cell development+++GO:0009615///response to virus+++GO:0051301///cell division+++GO:0042063///gliogenesis+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0021670///lateral ventricle development+++GO:0045596///negative regulation of cell differentiation+++GO:0045638///negative regulation of myeloid cell differentiation+++GO:0006468///protein phosphorylation+++GO:0045646///regulation of erythrocyte differentiation+++GO:0030154///cell differentiation+++GO:0008285///negative regulation of cell proliferation+++GO:2000773///negative regulation of cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0042127///regulation of cell proliferation+++GO:0021542///dentate gyrus development+++GO:0010468///regulation of gene expression+++GO:0045786///negative regulation of cell cycle+++GO:0007050///cell cycle arrest","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR028788///Cyclin-dependent kinase 6+++IPR008271///Serine/threonine-protein kinase, active site","[CDK6_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 6; EC=2.7.11.22; AltName: Full=Cell division protein kinase 6; AltName: Full=Serine/threonine-protein kinase PLSTIRE;"]
[10210,"'TOPORS'",279,379,329,null,"H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005814///centriole+++GO:0000151///ubiquitin ligase complex+++GO:0000930///gamma-tubulin complex+++GO:0030496///midbody+++GO:0032391///photoreceptor connecting cilium+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005868///cytoplasmic dynein complex+++GO:0036064///ciliary basal body+++GO:0016605///PML body+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0019789///SUMO transferase activity+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0044547///DNA topoisomerase binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003823///antigen binding","GO:0000209///protein polyubiquitination+++GO:0034504///protein localization to nucleus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006351///transcription, DNA-templated+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0042127///regulation of cell proliferation+++GO:0016925///protein sumoylation+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0010842///retina layer formation+++GO:0046548///retinal rod cell development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0035845///photoreceptor cell outer segment organization+++GO:0051457///maintenance of protein location in nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0046549///retinal cone cell development+++GO:0006513///protein monoubiquitination","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR017907///Zinc finger, RING-type, conserved site","[TOPRS_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Topors; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase Topors {ECO:0000305}; AltName: Full=SUMO1-protein E3 ligase Topors; AltName: Full=Topoisomerase I-binding RING finger protein; AltName: Full=Topoisomerase I-binding arginine/serine-rich protein; AltName: Full=Tumor suppressor p53-binding protein 3; Short=p53-binding protein 3; Short=p53BP3;"]
[10211,"'FLOT1'",1207,1015,1111,"04910///Insulin signaling pathway",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0044853///plasma membrane raft+++GO:0042383///sarcolemma+++GO:0016600///flotillin complex+++GO:0005815///microtubule organizing center+++GO:0048786///presynaptic active zone+++GO:0005765///lysosomal membrane+++GO:0098793///presynapse+++GO:0042470///melanosome+++GO:0030027///lamellipodium+++GO:0005768///endosome+++GO:0045121///membrane raft+++GO:0005913///cell-cell adherens junction+++GO:0016323///basolateral plasma membrane+++GO:0044291///cell-cell contact zone+++GO:0098978///glutamatergic synapse+++GO:0005901///caveola+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0001931///uropod+++GO:0045202///synapse+++GO:0009897///external side of plasma membrane+++GO:0098982///GABA-ergic synapse+++GO:0016324///apical plasma membrane+++GO:0005911///cell-cell junction+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0008180///COP9 signalosome+++GO:0098691///dopaminergic synapse+++GO:0034451///centriolar satellite+++GO:0030864///cortical actin cytoskeleton+++GO:0005769///early endosome","GO:0046982///protein heterodimerization activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0002020///protease binding+++GO:0005515///protein binding","GO:1903044///protein localization to membrane raft+++GO:0032728///positive regulation of interferon-beta production+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0034141///positive regulation of toll-like receptor 3 signaling pathway+++GO:0032092///positive regulation of protein binding+++GO:0001765///membrane raft assembly+++GO:1901890///positive regulation of cell junction assembly+++GO:0022617///extracellular matrix disassembly+++GO:0051580///regulation of neurotransmitter uptake+++GO:0070528///protein kinase C signaling+++GO:0007409///axonogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0050821///protein stabilization+++GO:1901741///positive regulation of myoblast fusion+++GO:0051260///protein homooligomerization+++GO:0044854///plasma membrane raft assembly+++GO:0034976///response to endoplasmic reticulum stress+++GO:0033227///dsRNA transport+++GO:0060355///positive regulation of cell adhesion molecule production+++GO:0002090///regulation of receptor internalization+++GO:0045807///positive regulation of endocytosis+++GO:0035023///regulation of Rho protein signal transduction+++GO:0001819///positive regulation of cytokine production+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0034143///regulation of toll-like receptor 4 signaling pathway+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071360///cellular response to exogenous dsRNA+++GO:0032226///positive regulation of synaptic transmission, dopaminergic","IPR036013///Band 7/SPFH domain superfamily+++IPR031905///Flotillin, C-terminal domain+++IPR027705///Flotillin family+++IPR001107///Band 7 domain","[FLOT1_HUMAN|Reviewed]RecName: Full=Flotillin-1;+++[A0A0G2JJQ6_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000409995}; Flags: Fragment;+++[A0A140T905_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388153}; Flags: Fragment;+++[A0A140T907_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388104}; Flags: Fragment;+++[A0A140T910_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000388517}; Flags: Fragment;+++[A0A140T957_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393145}; Flags: Fragment;+++[A0A140T959_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000392736}; Flags: Fragment;+++[A0A140T974_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000393767}; Flags: Fragment;+++[A0A140T9B1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000397108}; Flags: Fragment;+++[A0A140T9C3_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398866}; Flags: Fragment;+++[A0A140T9H7_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000403574}; Flags: Fragment;+++[A0A140T9L9_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000407101}; Flags: Fragment;+++[A0A140T9R1_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000410658}; Flags: Fragment;+++[A0A140T9W4_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415215}; Flags: Fragment;+++[A0A140T9X0_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000415104}; Flags: Fragment;+++[A2AB09_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000395333}; Flags: Fragment;+++[A2AB10_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000400615}; Flags: Fragment;+++[A2AB11_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000412058}; Flags: Fragment;+++[A2AB12_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000398834}; Flags: Fragment;+++[A2AB13_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000391341}; Flags: Fragment;+++[A2ABJ5_HUMAN|Unreviewed]SubName: Full=Flotillin-1 {ECO:0000313|Ensembl:ENSP00000404300}; Flags: Fragment;+++[A2VCL5_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:AAI28155.1}; Flags: Fragment;+++[Q5ST80_HUMAN|Unreviewed]SubName: Full=FLOT1 {ECO:0000313|EMBL:AQY76816.1}; SubName: Full=FLOT1 protein {ECO:0000313|EMBL:BAF31269.1}; SubName: Full=Flotillin 1 {ECO:0000313|EMBL:AAP35740.1}; SubName: Full=Flotillin 1, isoform CRA_b {ECO:0000313|EMBL:EAX03326.1};+++[Q6IB58_HUMAN|Unreviewed]SubName: Full=FLOT1 protein {ECO:0000313|EMBL:CAG33227.1};"]
[10212,"'DDX39A'",342,269,305.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001650///Helicase, C-terminal+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR014014///RNA helicase, DEAD-box type, Q motif+++IPR011545///DEAD/DEAH box helicase domain","[DX39A_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase DDX39A; EC=3.6.4.13; AltName: Full=DEAD box protein 39; AltName: Full=Nuclear RNA helicase URH49;+++[A0A024R7H0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 39, isoform CRA_b {ECO:0000313|EMBL:EAW84416.1};+++[A0A0D9SEM9_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000485838}; Flags: Fragment;+++[K7EIL8_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000464801}; Flags: Fragment;+++[K7EL56_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000465926}; Flags: Fragment;+++[K7EN69_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000466810}; Flags: Fragment;+++[K7ENP6_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467040}; Flags: Fragment;+++[K7EPJ3_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467411}; Flags: Fragment;+++[K7EQN7_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase DDX39A {ECO:0000313|Ensembl:ENSP00000467911}; Flags: Fragment;"]
[10213,"'PSMD14'",520,448,484,"05169///Epstein-Barr virus infection+++03050///Proteasome",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0031597///cytosolic proteasome complex+++GO:0008541///proteasome regulatory particle, lid subcomplex+++GO:0000502///proteasome complex+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0034774///secretory granule lumen+++GO:0005634///nucleus+++GO:0022624///proteasome accessory complex+++GO:1904813///ficolin-1-rich granule lumen","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0061133///endopeptidase activator activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0070628///proteasome binding+++GO:0016787///hydrolase activity","GO:0006281///DNA repair+++GO:0043312///neutrophil degranulation+++GO:0070536///protein K63-linked deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010950///positive regulation of endopeptidase activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006508///proteolysis+++GO:0000724///double-strand break repair via homologous recombination+++GO:0043687///post-translational protein modification+++GO:0045471///response to ethanol+++GO:0016579///protein deubiquitination+++GO:0061136///regulation of proteasomal protein catabolic process","IPR035299///26S Proteasome non-ATPase regulatory subunit 14+++IPR037518///MPN domain+++IPR000555///JAB1/MPN/MOV34 metalloenzyme domain+++IPR024969///Rpn11/EIF3F, C-terminal","[PSDE_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 14; EC=3.4.19.-; AltName: Full=26S proteasome regulatory subunit RPN11; AltName: Full=26S proteasome-associated PAD1 homolog 1;+++[A0A140VKF2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 69n {ECO:0000313|EMBL:AEE61289.1};+++[C9JW37_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 14 {ECO:0000313|Ensembl:ENSP00000399311}; Flags: Fragment;+++[Q4ZG77_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAX88940.1}; Flags: Fragment;+++[Q53TH1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PSMD14 {ECO:0000313|EMBL:AAY15016.1}; Flags: Fragment;"]
[102157402,"'AK6'",90.98,58.5,74.74,"00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03008///Ribosome biogenesis in eukaryotes",null,"M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP","R00127///ATP:AMP phosphotransferase   ATP + AMP <=> 2 ADP+++R01547///ATP:dAMP phosphotransferase   ATP + dAMP <=> ADP + dADP","GO:0000790///nuclear chromatin+++GO:0005669///transcription factor TFIID complex+++GO:0031389///Rad17 RFC-like complex+++GO:0005737///cytoplasm+++GO:0071339///MLL1 complex+++GO:0005829///cytosol+++GO:0000125///PCAF complex+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0033276///transcription factor TFTC complex+++GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0003713///transcription coactivator activity+++GO:0002039///p53 binding+++GO:0003677///DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005524///ATP binding+++GO:0033613///activating transcription factor binding+++GO:0051117///ATPase binding+++GO:0070742///C2H2 zinc finger domain binding+++GO:0003689///DNA clamp loader activity+++GO:0003682///chromatin binding+++GO:0050145///nucleoside monophosphate kinase activity+++GO:0004017///adenylate kinase activity+++GO:0016887///ATPase activity","GO:0030307///positive regulation of cell growth+++GO:0043966///histone H3 acetylation+++GO:0033314///mitotic DNA replication checkpoint+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008156///negative regulation of DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000492///box C/D snoRNP assembly+++GO:0060760///positive regulation of response to cytokine stimulus+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0000077///DNA damage checkpoint+++GO:0006366///transcription by RNA polymerase II+++GO:0042325///regulation of phosphorylation+++GO:0050821///protein stabilization+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0070555///response to interleukin-1+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0043066///negative regulation of apoptotic process+++GO:0006260///DNA replication+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0000076///DNA replication checkpoint+++GO:0007093///mitotic cell cycle checkpoint","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR020618///Adenylate kinase isoenzyme 6","[KAD6_HUMAN|Reviewed]RecName: Full=Adenylate kinase isoenzyme 6 {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK6 {ECO:0000255|HAMAP-Rule:MF_03173}; EC=2.7.4.3 {ECO:0000255|HAMAP-Rule:MF_03173}; AltName: Full=Adrenal gland protein AD-004; AltName: Full=Coilin-interacting nuclear ATPase protein {ECO:0000255|HAMAP-Rule:MF_03173}; Short=hCINAP; AltName: Full=Dual activity adenylate kinase/ATPase {ECO:0000255|HAMAP-Rule:MF_03173}; Short=AK/ATPase {ECO:0000255|HAMAP-Rule:MF_03173};+++[A0A087WVD7_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000479366};+++[A0A087WY94_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000481620};+++[D6RDH4_HUMAN|Unreviewed]SubName: Full=Adenylate kinase isoenzyme 6 {ECO:0000313|Ensembl:ENSP00000420947};"]
[10216,"'PRG4'",2,0,1,{"$nulls":4},"GO:0062023///collagen-containing extracellular matrix","GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0030247///polysaccharide binding+++GO:0005044///scavenger receptor activity","GO:0008283///cell proliferation+++GO:0006955///immune response","IPR001212///Somatomedin B domain+++IPR000585///Hemopexin-like domain+++IPR036024///Somatomedin B-like domain superfamily+++IPR020436///Somatomedin B, chordata+++IPR018486///Hemopexin, conserved site+++IPR036375///Hemopexin-like domain superfamily+++IPR018487///Hemopexin-like repeats","[PRG4_HUMAN|Reviewed]RecName: Full=Proteoglycan 4; AltName: Full=Lubricin; AltName: Full=Megakaryocyte-stimulating factor; AltName: Full=Superficial zone proteoglycan; Contains: RecName: Full=Proteoglycan 4 C-terminal part; Flags: Precursor;+++[A0A0U1RR20_HUMAN|Unreviewed]SubName: Full=Proteoglycan 4 {ECO:0000313|Ensembl:ENSP00000489292};"]
[10217,"'CTDSPL'",234,258,246,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0046872///metal ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0016787///hydrolase activity","GO:0016311///dephosphorylation+++GO:0006470///protein dephosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0008150///biological_process","IPR011948///Dullard phosphatase domain, eukaryotic+++IPR004274///FCP1 homology domain+++IPR036412///HAD-like superfamily+++IPR040078///CTD small RNA polymerase II polypeptide A phosphatase-like+++IPR023214///HAD superfamily","[CTDSL_HUMAN|Reviewed]RecName: Full=CTD small phosphatase-like protein; Short=CTDSP-like; EC=3.1.3.16; AltName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; AltName: Full=NIF-like protein; AltName: Full=Nuclear LIM interactor-interacting factor 1; Short=NLI-interacting factor 1; AltName: Full=Protein YA22; Short=hYA22; AltName: Full=RBSP3; AltName: Full=Small C-terminal domain phosphatase 3; Short=SCP3; Short=Small CTD phosphatase 3;+++[A0A024R2L8_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like, isoform CRA_c {ECO:0000313|EMBL:EAW64505.1};+++[F8WED2_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000408183};+++[H7C2B9_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000404977}; Flags: Fragment;+++[H7C2S4_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000407443}; Flags: Fragment;+++[H7C353_HUMAN|Unreviewed]SubName: Full=CTD small phosphatase-like protein {ECO:0000313|Ensembl:ENSP00000409600}; Flags: Fragment;"]
[10218,"'ANGPTL7'",426,512,469,{"$nulls":4},"GO:0005576///extracellular region","GO:0005515///protein binding","GO:0006979///response to oxidative stress","IPR002181///Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain+++IPR036056///Fibrinogen-like, C-terminal","[ANGL7_HUMAN|Reviewed]RecName: Full=Angiopoietin-related protein 7; AltName: Full=Angiopoietin-like factor; AltName: Full=Angiopoietin-like protein 7; AltName: Full=Cornea-derived transcript 6 protein; Flags: Precursor;"]
[1022,"'CDK7'",296,214,255,"04110///Cell cycle+++03022///Basal transcription factors+++03420///Nucleotide excision repair",null,"M00290///Holo-TFIIH complex",null,"GO:0070985///transcription factor TFIIK complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0005675///transcription factor TFIIH holo complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0003713///transcription coactivator activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0050681///androgen receptor binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0008022///protein C-terminus binding+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0007050///cell cycle arrest+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0007049///cell cycle+++GO:0030521///androgen receptor signaling pathway+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051301///cell division+++GO:0008283///cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0050821///protein stabilization+++GO:0006366///transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006370///7-methylguanosine mRNA capping+++GO:0006468///protein phosphorylation+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0016310///phosphorylation+++GO:0006363///termination of RNA polymerase I transcription","IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR037770///Cyclin-dependent kinase 7+++IPR017441///Protein kinase, ATP binding site","[CDK7_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 7; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=39 kDa protein kinase; Short=p39 Mo15; AltName: Full=CDK-activating kinase 1; AltName: Full=Cell division protein kinase 7; AltName: Full=Serine/threonine-protein kinase 1; AltName: Full=TFIIH basal transcription factor complex kinase subunit;+++[A0A0S2Z3F9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), isoform CRA_a {ECO:0000313|EMBL:EAW51300.1}; SubName: Full=Cyclin-dependent kinase 7 isoform 1 {ECO:0000313|EMBL:ALQ33428.1}; Flags: Fragment;+++[D6R9G1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422121};+++[D6R9Z2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422027};+++[D6RAD4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000422737};+++[D6REC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425043}; Flags: Fragment;+++[D6RF14_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000421559};+++[D6RFL0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 isoform 3 {ECO:0000313|EMBL:ALQ33429.1};+++[D6RGG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000426372};+++[D6RI01_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425983};+++[D6RIG9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 7 {ECO:0000313|Ensembl:ENSP00000425893};+++[Q14495_HUMAN|Unreviewed]SubName: Full=Protein kinase {ECO:0000313|EMBL:CAA53766.1}; Flags: Fragment;"]
[10220,"'GDF11'",1060,1029,1044.5,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005575///cellular_component+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005125///cytokine activity+++GO:0008083///growth factor activity","GO:0060021///roof of mouth development+++GO:0007399///nervous system development+++GO:0048593///camera-type eye morphogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0048468///cell development+++GO:0008285///negative regulation of cell proliferation+++GO:0060395///SMAD protein signal transduction+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0010469///regulation of signaling receptor activity+++GO:0043408///regulation of MAPK cascade+++GO:0001501///skeletal system development+++GO:0031016///pancreas development+++GO:0007498///mesoderm development+++GO:0001656///metanephros development+++GO:0021512///spinal cord anterior/posterior patterning+++GO:0048469///cell maturation+++GO:0042981///regulation of apoptotic process+++GO:0009887///animal organ morphogenesis+++GO:0001657///ureteric bud development+++GO:0009952///anterior/posterior pattern specification+++GO:0045596///negative regulation of cell differentiation","IPR001839///Transforming growth factor-beta, C-terminal+++IPR015615///Transforming growth factor-beta-related+++IPR029034///Cystine-knot cytokine+++IPR017948///Transforming growth factor beta, conserved site+++IPR001111///TGF-beta, propeptide","[GDF11_HUMAN|Reviewed]RecName: Full=Growth/differentiation factor 11 {ECO:0000303|PubMed:10391213}; Short=GDF-11; AltName: Full=Bone morphogenetic protein 11 {ECO:0000303|PubMed:10075854}; Short=BMP-11; Flags: Precursor;+++[A0A024RB20_HUMAN|Unreviewed]SubName: Full=Growth differentiation factor 11, isoform CRA_a {ECO:0000313|EMBL:EAW96831.1};+++[H0YI30_HUMAN|Unreviewed]SubName: Full=Growth/differentiation factor 11 {ECO:0000313|Ensembl:ENSP00000448390}; Flags: Fragment;"]
[10221,"'TRIB1'",325,345,335,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004672///protein kinase activity+++GO:0005515///protein binding+++GO:0004860///protein kinase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0055106///ubiquitin-protein transferase regulator activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0005524///ATP binding","GO:0006469///negative regulation of protein kinase activity+++GO:0006468///protein phosphorylation+++GO:0045659///negative regulation of neutrophil differentiation+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0043405///regulation of MAP kinase activity+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0007254///JNK cascade+++GO:0032496///response to lipopolysaccharide+++GO:0045645///positive regulation of eosinophil differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0045651///positive regulation of macrophage differentiation+++GO:0048662///negative regulation of smooth muscle cell proliferation","IPR024105///Tribbles homologue 1+++IPR011009///Protein kinase-like domain superfamily+++IPR024104///Pseudokinase tribbles family/serine-threonine-protein kinase 40+++IPR000719///Protein kinase domain","[TRIB1_HUMAN|Reviewed]RecName: Full=Tribbles homolog 1; Short=TRB-1; AltName: Full=G-protein-coupled receptor-induced gene 2 protein; Short=GIG-2; AltName: Full=SKIP1;+++[E5RFH4_HUMAN|Unreviewed]SubName: Full=Tribbles homolog 1 {ECO:0000313|Ensembl:ENSP00000428879};"]
[10223,"'GPA33'",5,9,7,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0038023///signaling receptor activity",null,"IPR003598///Immunoglobulin subtype 2+++IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003599///Immunoglobulin subtype+++IPR013106///Immunoglobulin V-set domain+++IPR007110///Immunoglobulin-like domain","[GPA33_HUMAN|Reviewed]RecName: Full=Cell surface A33 antigen; AltName: Full=Glycoprotein A33; Flags: Precursor;+++[A0A0J9YXH7_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000488407}; Flags: Fragment;+++[E9PMB2_HUMAN|Unreviewed]SubName: Full=Cell surface A33 antigen {ECO:0000313|Ensembl:ENSP00000431195};"]
[10224,"'ZNF443'",9.93,5,7.465,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily","[ZN443_HUMAN|Reviewed]RecName: Full=Zinc finger protein 443; AltName: Full=Krueppel-type zinc finger protein ZK1;+++[F8WDY2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 443 {ECO:0000313|Ensembl:ENSP00000389105};"]
[10225,"'CD96'",8.03,10.64,9.335,null,"H01008///C syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm+++GO:0005912///adherens junction+++GO:0005886///plasma membrane",null,"GO:0007160///cell-matrix adhesion+++GO:0002728///negative regulation of natural killer cell cytokine production+++GO:0006955///immune response+++GO:0032496///response to lipopolysaccharide+++GO:0002534///cytokine production involved in inflammatory response+++GO:0007155///cell adhesion+++GO:0032689///negative regulation of interferon-gamma production+++GO:0050776///regulation of immune response","IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain+++IPR003599///Immunoglobulin subtype","[TACT_HUMAN|Reviewed]RecName: Full=T-cell surface protein tactile; AltName: Full=Cell surface antigen CD96; AltName: Full=T cell-activated increased late expression protein; AltName: CD_antigen=CD96; Flags: Precursor;+++[E9PEJ1_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417152};+++[F8WDV3_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417680};+++[H7C4F0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000417150}; Flags: Fragment;+++[L8EAH0_HUMAN|Unreviewed]SubName: Full=Alternative protein CD96 {ECO:0000313|EMBL:CCQ43338.1};+++[Q8WUE2_HUMAN|Unreviewed]SubName: Full=CD96 antigen, isoform CRA_b {ECO:0000313|EMBL:EAW79697.1}; SubName: Full=CD96 protein {ECO:0000313|EMBL:AAH20749.1}; SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000389801};+++[U3KPT0_HUMAN|Unreviewed]SubName: Full=T-cell surface protein tactile {ECO:0000313|Ensembl:ENSP00000475194}; Flags: Fragment;"]
[10226,"'PLIN3'",1765,1411,1588,{"$nulls":4},"GO:0010008///endosome membrane+++GO:0030133///transport vesicle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005811///lipid droplet+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005768///endosome","GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0016192///vesicle-mediated transport","IPR004279///Perilipin","[PLIN3_HUMAN|Reviewed]RecName: Full=Perilipin-3; AltName: Full=47 kDa mannose 6-phosphate receptor-binding protein; Short=47 kDa MPR-binding protein; AltName: Full=Cargo selection protein TIP47; AltName: Full=Mannose-6-phosphate receptor-binding protein 1; AltName: Full=Placental protein 17; Short=PP17;+++[A0A140VJN8_HUMAN|Unreviewed]RecName: Full=Perilipin {ECO:0000256|PIRNR:PIRNR036881};+++[K7EJD0_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465117}; Flags: Fragment;+++[K7EL96_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000465975}; Flags: Fragment;+++[K7ER39_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468096}; Flags: Fragment;+++[K7ERZ3_HUMAN|Unreviewed]SubName: Full=Perilipin-3 {ECO:0000313|Ensembl:ENSP00000468476}; Flags: Fragment;"]
[10227,"'MFSD10'",2615,2663,2639,{"$nulls":4},"GO:0016020///membrane+++GO:0031526///brush border membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016021///integral component of membrane","GO:0008514///organic anion transmembrane transporter activity+++GO:0008493///tetracycline transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006915///apoptotic process+++GO:0043252///sodium-independent organic anion transport+++GO:0015904///tetracycline transport","IPR036259///MFS transporter superfamily+++IPR011701///Major facilitator superfamily+++IPR020846///Major facilitator superfamily domain","[MFS10_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 10; AltName: Full=Tetracycline transporter-like protein;+++[D6R9N3_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423509};+++[D6RA47_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000423402};+++[D6RE79_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000426907};+++[D6RHV1_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000427637};+++[D6RIZ4_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000425757};"]
[10228,"'STX6'",371,399,385,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0000139///Golgi membrane+++GO:0005769///early endosome+++GO:0030136///clathrin-coated vesicle+++GO:0005654///nucleoplasm+++GO:0032588///trans-Golgi network membrane+++GO:0045335///phagocytic vesicle+++GO:0016021///integral component of membrane+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0008021///synaptic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0031201///SNARE complex","GO:0005484///SNAP receptor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding+++GO:0019905///syntaxin binding","GO:0016192///vesicle-mediated transport+++GO:0032880///regulation of protein localization+++GO:0048278///vesicle docking+++GO:0032456///endocytic recycling+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0006906///vesicle fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0048193///Golgi vesicle transport+++GO:0090161///Golgi ribbon formation+++GO:0007032///endosome organization+++GO:1903827///regulation of cellular protein localization+++GO:0016189///synaptic vesicle to endosome fusion","IPR006012///Syntaxin/epimorphin, conserved site+++IPR015260///Syntaxin 6, N-terminal+++IPR000727///Target SNARE coiled-coil homology domain+++IPR010989///SNARE","[STX6_HUMAN|Reviewed]RecName: Full=Syntaxin-6;"]
[102288414,"'C11orf98'",505.15,350.15,427.65,{"$nulls":7},"IPR037691///Uncharacterized protein C11orf98","[CK098_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C11orf98 {ECO:0000305};+++[A0A0B4J220_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 48, isoform CRA_c {ECO:0000313|EMBL:EAW74054.1};+++[L0R588_HUMAN|Unreviewed]SubName: Full=Alternative protein C11orf48 {ECO:0000313|EMBL:CCO13689.1};"]
[10229,"'COQ7'",77,112,94.5,"01100///Metabolic pathways+++00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01110///Biosynthesis of secondary metabolites","H00999///Coenzyme Q10 deficiency","M00128///Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone","R08775///2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O+++R04984///2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone,acceptor:oxygen oxidoreductase (5-hydroxylating)   2-Hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Reduced acceptor + Oxygen <=> 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + Acceptor + H2O","GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008682///2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity+++GO:0004497///monooxygenase activity+++GO:0016709///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008340///determination of adult lifespan+++GO:0006744///ubiquinone biosynthetic process+++GO:0042493///response to drug+++GO:0042775///mitochondrial ATP synthesis coupled electron transport+++GO:0055114///oxidation-reduction process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:2000377///regulation of reactive oxygen species metabolic process","IPR011566///Ubiquinone biosynthesis protein Coq7+++IPR009078///Ferritin-like superfamily","[COQ7_HUMAN|Reviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000255|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000255|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000255|HAMAP-Rule:MF_03194}; Flags: Precursor;+++[H3BP28_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[H3BS11_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456490};+++[H3BSZ3_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456943}; Flags: Fragment;+++[H3BTN8_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457256}; Flags: Fragment;+++[I3L1T0_HUMAN|Unreviewed]SubName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000313|Ensembl:ENSP00000459076}; SubName: Full=Coenzyme Q7 homolog, ubiquinone (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW50269.1};+++[Q49A71_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};+++[Q8NI45_HUMAN|Unreviewed]RecName: Full=5-demethoxyubiquinone hydroxylase, mitochondrial {ECO:0000256|HAMAP-Rule:MF_03194}; Short=DMQ hydroxylase {ECO:0000256|HAMAP-Rule:MF_03194}; EC=1.14.13.- {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Timing protein clk-1 homolog {ECO:0000256|HAMAP-Rule:MF_03194}; AltName: Full=Ubiquinone biosynthesis monooxygenase COQ7 {ECO:0000256|HAMAP-Rule:MF_03194};"]
[10231,"'RCAN2'",297,376,336.5,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005575///cellular_component+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0008597///calcium-dependent protein serine/threonine phosphatase regulator activity+++GO:0005515///protein binding","GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0019722///calcium-mediated signaling","IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR035979///RNA-binding domain superfamily+++IPR034921///Calcipressin-2+++IPR034919///Calcipressin-2, RNA recognition motif+++IPR006931///Calcipressin","[RCAN2_HUMAN|Reviewed]RecName: Full=Calcipressin-2; AltName: Full=Down syndrome candidate region 1-like 1; AltName: Full=Myocyte-enriched calcineurin-interacting protein 2; Short=MCIP2; AltName: Full=Regulator of calcineurin 2; AltName: Full=Thyroid hormone-responsive protein ZAKI-4;+++[A0A0A0MSB6_HUMAN|Unreviewed]SubName: Full=Calcipressin-2 {ECO:0000313|Ensembl:ENSP00000384317};+++[A8MXP8_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000378347};+++[B2R612_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92723, highly similar to Homo sapiens Down syndrome critical region gene 1-like 1 (DSCR1L1), mRNA {ECO:0000313|EMBL:BAG35309.1};+++[H0YL43_HUMAN|Unreviewed]SubName: Full=Reticulocalbin-2 {ECO:0000313|Ensembl:ENSP00000453052}; Flags: Fragment;+++[L0R6N1_HUMAN|Unreviewed]SubName: Full=Alternative protein RCAN2 {ECO:0000313|EMBL:CCO13800.1};+++[L8E7F0_HUMAN|Unreviewed]SubName: Full=Alternative protein RCN2 {ECO:0000313|EMBL:CCQ43195.1};+++[Q86YJ0_HUMAN|Unreviewed]SubName: Full=RCAN2 protein {ECO:0000313|EMBL:AAH38509.1};"]
[10232,"'MSLN'",18,7,12.5,{"$nulls":4},"GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0044267///cellular protein metabolic process+++GO:0007155///cell adhesion+++GO:0007160///cell-matrix adhesion+++GO:0031016///pancreas development+++GO:0043687///post-translational protein modification","IPR026664///Stereocilin-related+++IPR010335///Mesothelin","[MSLN_HUMAN|Reviewed]RecName: Full=Mesothelin; AltName: Full=CAK1 antigen; AltName: Full=Pre-pro-megakaryocyte-potentiating factor; Contains: RecName: Full=Megakaryocyte-potentiating factor; Short=MPF; Contains: RecName: Full=Mesothelin, cleaved form; Flags: Precursor;+++[H3BMA1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000454295}; Flags: Fragment;+++[H3BR90_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000456132}; Flags: Fragment;+++[H3BUX1_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000457847}; Flags: Fragment;+++[H3BV92_HUMAN|Unreviewed]SubName: Full=Mesothelin {ECO:0000313|Ensembl:ENSP00000458003}; Flags: Fragment;"]
[10233,"'LRRC23'",63,65,64,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily","[LRC23_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 23; AltName: Full=Leucine-rich protein B7;+++[A8K8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77436, highly similar to Homo sapiens B7 gene (B7), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF85056.1};+++[C9JEW3_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000396049};+++[C9JKE8_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000402554};+++[C9JQN5_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000408066}; Flags: Fragment;+++[E9PDZ4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000397192};+++[F2Z299_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 23 {ECO:0000313|Ensembl:ENSP00000392623};"]
[10234,"'LRRC17'",2479,2965,2722,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005615///extracellular space",null,"GO:0033687///osteoblast proliferation+++GO:0048539///bone marrow development+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0001649///osteoblast differentiation+++GO:0001503///ossification","IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily+++IPR003591///Leucine-rich repeat, typical subtype+++IPR000483///Cysteine-rich flanking region, C-terminal","[LRC17_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 17; AltName: Full=p37NB; Flags: Precursor;+++[C9JT74_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 17 {ECO:0000313|Ensembl:ENSP00000394194}; Flags: Fragment;"]
[10235,"'RASGRP2'",9,15,12,"04062///Chemokine signaling pathway+++04015///Rap1 signaling pathway+++04010///MAPK signaling pathway+++05200///Pathways in cancer+++04014///Ras signaling pathway+++04611///Platelet activation","H01235///Bleeding disorder platelet-type",null,null,"GO:0043005///neuron projection+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0008289///lipid binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0001558///regulation of cell growth+++GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0035556///intracellular signal transduction+++GO:0007265///Ras protein signal transduction+++GO:0071277///cellular response to calcium ion","IPR008937///Ras-like guanine nucleotide exchange factor+++IPR001895///Ras guanine-nucleotide exchange factors catalytic domain+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR011992///EF-hand domain pair+++IPR018247///EF-Hand 1, calcium-binding site+++IPR000651///Ras-like guanine nucleotide exchange factor, N-terminal+++IPR036964///Ras guanine-nucleotide exchange factor catalytic domain superfamily+++IPR023578///Ras guanine nucleotide exchange factor domain superfamily+++IPR002048///EF-hand domain","[GRP2_HUMAN|Reviewed]RecName: Full=RAS guanyl-releasing protein 2; AltName: Full=Calcium and DAG-regulated guanine nucleotide exchange factor I; Short=CalDAG-GEFI; AltName: Full=Cdc25-like protein; Short=hCDC25L; AltName: Full=F25B3.3 kinase-like protein;+++[A6NHE2_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366705}; Flags: Fragment;+++[A6NJ28_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000366706};+++[A8MTF9_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377950};+++[A8MVK8_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000377949};+++[B3KV60_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16161 fis, clone BRCAN2012110, highly similar to Homo sapiens RAS guanyl releasing protein 2 (calcium and DAG-regulated) (RASGRP2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53672.1};+++[C9JKH6_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000389068}; Flags: Fragment;+++[C9JZ82_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000401314}; Flags: Fragment;+++[E7EM78_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399114}; Flags: Fragment;+++[E7EMB4_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000399028};+++[E7EWQ7_HUMAN|Unreviewed]SubName: Full=RAS guanyl-releasing protein 2 {ECO:0000313|Ensembl:ENSP00000396029};+++[Q2YDB1_HUMAN|Unreviewed]SubName: Full=RASGRP2 protein {ECO:0000313|EMBL:AAI10307.1}; Flags: Fragment;"]
[10236,"'HNRNPR'",879,920,899.5,{"$nulls":4},"GO:0071013///catalytic step 2 spliceosome+++GO:0005737///cytoplasm+++GO:0043679///axon terminus+++GO:0030426///growth cone+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0005681///spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0030425///dendrite","GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0061157///mRNA destabilization+++GO:0043086///negative regulation of catalytic activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0008380///RNA splicing+++GO:0016070///RNA metabolic process+++GO:0061014///positive regulation of mRNA catabolic process","IPR000504///RNA recognition motif domain+++IPR034411///Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2+++IPR034410///Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 1+++IPR035979///RNA-binding domain superfamily+++IPR006535///HnRNP R/Q splicing factor+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[HNRPR_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein R; Short=hnRNP R;+++[A0A286YEZ8_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|Ensembl:ENSP00000493186}; Flags: Fragment;+++[B4DMB1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53358, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59823.1};+++[B4DMD1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53360, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG59843.1};+++[B4DT28_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein R, isoform CRA_a {ECO:0000313|EMBL:EAW95040.1}; SubName: Full=cDNA FLJ54544, highly similar to Heterogeneous nuclear ribonucleoprotein R {ECO:0000313|EMBL:BAG61840.1};+++[Q0VGD6_HUMAN|Unreviewed]SubName: Full=HNRPR protein {ECO:0000313|EMBL:AAI10390.1}; Flags: Fragment;+++[Q6MZS5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686A13234 {ECO:0000313|EMBL:CAE45953.1}; Flags: Fragment;"]
[10237,"'SLC35B1'",511,514,512.5,{"$nulls":4},"GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005459///UDP-galactose transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0072334///UDP-galactose transmembrane transport+++GO:0008643///carbohydrate transport","IPR013657///UAA transporter","[S35B1_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member B1; AltName: Full=UDP-galactose transporter-related protein 1; Short=UGTrel1; Short=hUGTrel1;+++[D3DTX1_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35, member B1, isoform CRA_a {ECO:0000313|EMBL:EAW94669.1};+++[D6R981_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000423323}; Flags: Fragment;+++[D6R9G9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000422104}; Flags: Fragment;+++[D6RB73_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424367}; Flags: Fragment;+++[D6RDY9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000425179};+++[D6RE58_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426961}; Flags: Fragment;+++[D6RF81_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000424857}; Flags: Fragment;+++[D6RG34_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000426402}; Flags: Fragment;+++[D6RHG0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member B1 {ECO:0000313|Ensembl:ENSP00000427689}; Flags: Fragment;"]
[10238,"'DCAF7'",1085.46,1228.9,1157.18,{"$nulls":4},"GO:0016363///nuclear matrix+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0043687///post-translational protein modification","IPR036322///WD40-repeat-containing domain superfamily+++IPR001680///WD40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR019775///WD40 repeat, conserved site+++IPR017986///WD40-repeat-containing domain","[DCAF7_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 7; AltName: Full=WD repeat-containing protein 68; AltName: Full=WD repeat-containing protein An11 homolog;+++[A0A087WWI6_HUMAN|Unreviewed]SubName: Full=DDB1- and CUL4-associated factor 7 {ECO:0000313|Ensembl:ENSP00000480250}; Flags: Fragment;"]
[10239,"'AP3S2'",347.37,435.25,391.31,"04142///Lysosome",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0030123///AP-3 adaptor complex+++GO:1904115///axon cytoplasm+++GO:0030117///membrane coat+++GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus",null,"GO:0048490///anterograde synaptic vesicle transport+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0008089///anterograde axonal transport+++GO:0015031///protein transport","IPR011012///Longin-like domain superfamily+++IPR016635///Adaptor protein complex, sigma subunit+++IPR000804///Clathrin adaptor complex, small chain+++IPR022775///AP complex, mu/sigma subunit","[AP3S2_HUMAN|Reviewed]RecName: Full=AP-3 complex subunit sigma-2; AltName: Full=AP-3 complex subunit sigma-3B; AltName: Full=Adaptor-related protein complex 3 subunit sigma-2; AltName: Full=Sigma-3B-adaptin; Short=Sigma3B-adaptin; AltName: Full=Sigma-adaptin 3b;+++[A0A024RC62_HUMAN|Unreviewed]SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_a {ECO:0000313|EMBL:EAX02073.1};+++[A0A087WY05_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000481434};+++[H0YKM3_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000452862};+++[H0YLI7_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453223}; SubName: Full=Adaptor-related protein complex 3, sigma 2 subunit, isoform CRA_d {ECO:0000313|EMBL:EAX02075.1};+++[H0YLX6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000453380};+++[H0YN38_HUMAN|Unreviewed]RecName: Full=AP complex subunit sigma {ECO:0000256|PIRNR:PIRNR015588};+++[H0YNI6_HUMAN|Unreviewed]SubName: Full=AP-3 complex subunit sigma-2 {ECO:0000313|Ensembl:ENSP00000454027};+++[Q6PK37_HUMAN|Unreviewed]SubName: Full=AP3S2 protein {ECO:0000313|EMBL:AAH07773.1}; Flags: Fragment;"]
[1024,"'CDK8'",285,264,274.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016592///mediator complex+++GO:0032991///protein-containing complex","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0006468///protein phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016310///phosphorylation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051726///regulation of cell cycle","IPR008271///Serine/threonine-protein kinase, active site+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain","[CDK8_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 8; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=Cell division protein kinase 8; AltName: Full=Mediator complex subunit CDK8; AltName: Full=Mediator of RNA polymerase II transcription subunit CDK8; AltName: Full=Protein kinase K35;+++[A0A0D9SEP3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000485883}; Flags: Fragment;+++[A0A0D9SFZ2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000487013}; Flags: Fragment;+++[F5H6D4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|Ensembl:ENSP00000437696};+++[Q64FY6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:AAU29339.1};+++[U4PPA3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 8 {ECO:0000313|EMBL:CDI06887.1}; Flags: Fragment;"]
[10240,"'MRPS31'",124,76,100,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05202///Transcriptional misregulation in cancer+++04137///Mitophagy - animal+++04140///Autophagy - animal+++04910///Insulin signaling pathway+++05200///Pathways in cancer+++05215///Prostate cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++04922///Glucagon signaling pathway+++04919///Thyroid hormone signaling pathway+++04068///FoxO signaling pathway+++04211///Longevity regulating pathway+++04213///Longevity regulating pathway - multiple species+++05165///Human papillomavirus infection+++04218///Cellular senescence","H00037///Alveolar rhabdomyosarcoma","M00676///PI3K-Akt signaling",null,"GO:0005763///mitochondrial small ribosomal subunit+++GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005743///mitochondrial inner membrane+++GO:0005730///nucleolus","GO:0003735///structural constituent of ribosome+++GO:0019904///protein domain specific binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation","IPR026299///Mitochondrial 28S ribosomal protein S31","[RT31_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S31, mitochondrial; Short=MRP-S31; Short=S31mt; AltName: Full=Imogen 38; AltName: Full=Mitochondrial small ribosomal subunit protein mS31 {ECO:0000303|PubMed:25838379}; Flags: Precursor;"]
[10241,"'CALCOCO2'",715,732,723.5,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0000421///autophagosome membrane+++GO:0005776///autophagosome+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0016032///viral process+++GO:0034341///response to interferon-gamma+++GO:1901098///positive regulation of autophagosome maturation+++GO:0006914///autophagy+++GO:0098792///xenophagy","IPR012852///Calcium binding and coiled-coil domain-like","[CACO2_HUMAN|Reviewed]RecName: Full=Calcium-binding and coiled-coil domain-containing protein 2; AltName: Full=Antigen nuclear dot 52 kDa protein; AltName: Full=Nuclear domain 10 protein NDP52 {ECO:0000305}; Short=Nuclear domain 10 protein 52 {ECO:0000303|PubMed:7540613}; AltName: Full=Nuclear dot protein 52 {ECO:0000303|PubMed:9230084};+++[D6RBF9_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424169}; Flags: Fragment;+++[D6RBI4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422697}; Flags: Fragment;+++[D6REB0_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425090}; Flags: Fragment;+++[D6RF70_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424889}; Flags: Fragment;+++[D6RJE7_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425692}; Flags: Fragment;+++[H0Y9G3_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424083}; Flags: Fragment;+++[H0YBP4_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000429963}; Flags: Fragment;+++[I3L493_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461083}; Flags: Fragment;+++[I3L4E1_HUMAN|Unreviewed]SubName: Full=Calcium-binding and coiled-coil domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000461184};"]
[10243,"'GPHN'",80,77,78.5,"00790///Folate biosynthesis+++01100///Metabolic pathways+++04727///GABAergic synapse","H00192///Xanthinuria+++H00769///Hyperekplexia",null,"R09735///adenylyl-molybdopterin:molybdate molybdate transferase (AMP-forming)   Adenylated molybdopterin + Molybdate <=> Molybdoenzyme molybdenum cofactor + AMP + H2O+++R09726///ATP:molybdopterin adenylyltransferase   ATP + Molybdopterin <=> Diphosphate + Adenylated molybdopterin","GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0099634///postsynaptic specialization membrane+++GO:0005856///cytoskeleton+++GO:0099572///postsynaptic specialization+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0014069///postsynaptic density+++GO:0030425///dendrite+++GO:0005829///cytosol","GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0061598///molybdopterin adenylyltransferase activity+++GO:0005524///ATP binding+++GO:0008940///nitrate reductase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0061599///molybdopterin molybdotransferase activity+++GO:0043546///molybdopterin cofactor binding","GO:0018315///molybdenum incorporation into molybdenum-molybdopterin complex+++GO:0055114///oxidation-reduction process+++GO:0032324///molybdopterin cofactor biosynthetic process+++GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0007529///establishment of synaptic specificity at neuromuscular junction+++GO:0008152///metabolic process+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0010038///response to metal ion+++GO:0072579///glycine receptor clustering+++GO:0097112///gamma-aminobutyric acid receptor clustering","IPR005110///MoeA, N-terminal and linker domain+++IPR008284///Molybdenum cofactor biosynthesis, conserved site+++IPR036135///MoeA, N-terminal and linker domain superfamily+++IPR036688///MoeA, C-terminal, domain IV superfamily+++IPR001453///MoaB/Mog domain+++IPR005111///MoeA, C-terminal, domain IV+++IPR038987///Molybdopterin biosynthesis protein MoeA-like+++IPR036425///MoaB/Mog-like domain superfamily","[GEPH_HUMAN|Reviewed]RecName: Full=Gephyrin {ECO:0000303|PubMed:10839351}; Includes: RecName: Full=Molybdopterin adenylyltransferase; Short=MPT adenylyltransferase; EC=2.7.7.75 {ECO:0000305|PubMed:26613940}; AltName: Full=Domain G; Includes: RecName: Full=Molybdopterin molybdenumtransferase; Short=MPT Mo-transferase; EC=2.10.1.1 {ECO:0000305|PubMed:22040219, ECO:0000305|PubMed:26613940}; AltName: Full=Domain E;+++[F5H039_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000438404};+++[G3V355_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451056};+++[G3V4D2_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451725};+++[G3V4R0_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000451935};+++[G3V582_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452220};+++[H0YIY4_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450442}; Flags: Fragment;+++[H0YJ30_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000450706}; Flags: Fragment;+++[H0YJR5_HUMAN|Unreviewed]SubName: Full=Gephyrin {ECO:0000313|Ensembl:ENSP00000452009}; Flags: Fragment;"]
[10244,"'RABEPK'",258,227,242.5,"04141///Protein processing in endoplasmic reticulum+++03060///Protein export+++04918///Thyroid hormone synthesis+++05020///Prion diseases",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0032588///trans-Golgi network membrane+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0005737///cytoplasm","GO:0051082///unfolded protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0051787///misfolded protein binding+++GO:0019904///protein domain specific binding+++GO:0043022///ribosome binding+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0016887///ATPase activity+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0051087///chaperone binding","GO:0006904///vesicle docking involved in exocytosis+++GO:0006898///receptor-mediated endocytosis","IPR006652///Kelch repeat type 1+++IPR011498///Kelch repeat type 2+++IPR015915///Kelch-type beta propeller","[RABEK_HUMAN|Reviewed]RecName: Full=Rab9 effector protein with kelch motifs; AltName: Full=40 kDa Rab9 effector protein; AltName: Full=p40;+++[A0A024R8A0_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 1 {ECO:0000313|EMBL:ALQ33965.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_c {ECO:0000313|EMBL:EAW87619.1};+++[A0A0S2Z4Z1_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 5 {ECO:0000313|EMBL:ALQ33969.1}; Flags: Fragment;+++[A0A0S2Z4Z5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 4 {ECO:0000313|EMBL:ALQ33968.1}; SubName: Full=Rab9 effector protein with kelch motifs, isoform CRA_d {ECO:0000313|EMBL:EAW87617.1}; Flags: Fragment;+++[A0A0S2Z506_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 3 {ECO:0000313|EMBL:ALQ33967.1};+++[A0A0S2Z553_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs isoform 2 {ECO:0000313|EMBL:ALQ33966.1};+++[Q5T1S4_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000362645};+++[Q5T1S5_HUMAN|Unreviewed]SubName: Full=Rab9 effector protein with kelch motifs {ECO:0000313|Ensembl:ENSP00000402234}; Flags: Fragment;"]
[10245,"'TIMM17B'",654,566,610,{"$nulls":4},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0005743///mitochondrial inner membrane","GO:0005515///protein binding+++GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport","IPR005678///Mitochondrial inner membrane translocase complex, subunit Tim17","[TI17B_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B;+++[Q8NCS3_HUMAN|Unreviewed]SubName: Full=TIMM17B protein {ECO:0000313|EMBL:AAH29446.1}; Flags: Fragment;+++[V9GYK7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000476861};+++[V9GYS0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477027};+++[V9GYU0_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit Tim17-B {ECO:0000313|Ensembl:ENSP00000477085}; Flags: Fragment;"]
[10247,"'RIDA'",81,72,76.5,{"$nulls":3},"R11099///2-iminopropanoate aminohydrolase   2-Iminopropanoate + H2O <=> Pyruvate + Ammonia+++R11098///2-iminobutanoate aminohydrolase   2-Iminobutanoate + H2O <=> 2-Oxobutanoate + Ammonia","GO:0005737///cytoplasm+++GO:0005777///peroxisome+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0042803///protein homodimerization activity+++GO:0036041///long-chain fatty acid binding+++GO:1904013///xenon atom binding+++GO:0016787///hydrolase activity+++GO:0046914///transition metal ion binding+++GO:0003723///RNA binding+++GO:0016892///endoribonuclease activity, producing 3'-phosphomonoesters+++GO:0043167///ion binding+++GO:0019239///deaminase activity+++GO:1904012///platinum binding","GO:1901565///organonitrogen compound catabolic process+++GO:0001822///kidney development+++GO:0019518///L-threonine catabolic process to glycine+++GO:1902074///response to salt+++GO:0070314///G1 to G0 transition+++GO:0017148///negative regulation of translation+++GO:0030324///lung development+++GO:0007420///brain development+++GO:0033993///response to lipid+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","IPR006175///YjgF/YER057c/UK114 family+++IPR019897///RidA, conserved site+++IPR035959///RutC-like superfamily+++IPR006056///RidA family","[RIDA_HUMAN|Reviewed]RecName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000305|PubMed:22094463}; EC=3.5.99.10 {ECO:0000269|PubMed:22094463}; AltName: Full=14.5 kDa translational inhibitor protein {ECO:0000303|PubMed:8973653}; Short=hp14.5 {ECO:0000303|PubMed:14997576}; Short=p14.5 {ECO:0000303|PubMed:8973653}; AltName: Full=Heat-responsive protein 12 {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Reactive intermediate imine deaminase A homolog {ECO:0000312|HGNC:HGNC:16897}; AltName: Full=Translation inhibitor L-PSP ribonuclease {ECO:0000250|UniProtKB:P52759}; EC=3.1.-.- {ECO:0000250|UniProtKB:P52759}; AltName: Full=UK114 antigen homolog {ECO:0000305|PubMed:20817725};+++[A0A024R9H2_HUMAN|Unreviewed]SubName: Full=Heat-responsive protein 12, isoform CRA_a {ECO:0000313|EMBL:EAW91775.1};+++[E5RIP8_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000429321};+++[H0YB34_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000428596}; Flags: Fragment;+++[H0YBX3_HUMAN|Unreviewed]SubName: Full=2-iminobutanoate/2-iminopropanoate deaminase {ECO:0000313|Ensembl:ENSP00000430482}; Flags: Fragment;"]
[10248,"'POP7'",636,408,522,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005634///nucleus+++GO:0000172///ribonuclease MRP complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0030681///multimeric ribonuclease P complex+++GO:0005655///nucleolar ribonuclease P complex+++GO:0005654///nucleoplasm","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0001682///tRNA 5'-leader removal+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0008033///tRNA processing","IPR036882///Alba-like domain superfamily+++IPR014612///Ribonucleases P/MRP protein subunit Rpp20","[POP7_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p20; Short=RNaseP protein p20; EC=3.1.26.5; AltName: Full=Ribonucleases P/MRP protein subunit POP7 homolog; Short=hPOP7;+++[C9JYM0_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p20 {ECO:0000313|Ensembl:ENSP00000387814}; Flags: Fragment;"]
[1025,"'CDK9'",805,638,721.5,"05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0005694///chromosome+++GO:0016020///membrane+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0008023///transcription elongation factor complex+++GO:0000790///nuclear chromatin+++GO:0008024///cyclin/CDK positive transcription elongation factor complex+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0016605///PML body+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0001223///transcription coactivator binding+++GO:0005515///protein binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0017069///snRNA binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding+++GO:0019901///protein kinase binding+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0008353///RNA polymerase II CTD heptapeptide repeat kinase activity+++GO:0016301///kinase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0004672///protein kinase activity+++GO:0030332///cyclin binding+++GO:0097322///7SK snRNA binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006281///DNA repair+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0031297///replication fork processing+++GO:0031056///regulation of histone modification+++GO:0006468///protein phosphorylation+++GO:0007346///regulation of mitotic cell cycle+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0071157///negative regulation of cell cycle arrest+++GO:1903839///positive regulation of mRNA 3'-UTR binding+++GO:0016310///phosphorylation+++GO:0070816///phosphorylation of RNA polymerase II C-terminal domain+++GO:0006282///regulation of DNA repair+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0042493///response to drug+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008283///cell proliferation+++GO:0051147///regulation of muscle cell differentiation+++GO:0032968///positive regulation of transcription elongation from RNA polymerase II promoter+++GO:0033129///positive regulation of histone phosphorylation+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0050434///positive regulation of viral transcription","IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[CDK9_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 9; EC=2.7.11.22; EC=2.7.11.23; AltName: Full=C-2K; AltName: Full=Cell division cycle 2-like protein kinase 4; AltName: Full=Cell division protein kinase 9; AltName: Full=Serine/threonine-protein kinase PITALRE; AltName: Full=Tat-associated kinase complex catalytic subunit;+++[A0A024R880_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 (CDC2-related kinase), isoform CRA_a {ECO:0000313|EMBL:EAW87697.1};+++[B5BU53_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|EMBL:BAG70103.1};+++[X6RE90_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 9 {ECO:0000313|Ensembl:ENSP00000395872}; Flags: Fragment;"]
[10250,"'SRRM1'",1998,2322,2160,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006405///RNA export from nucleus+++GO:0031124///mRNA 3'-end processing+++GO:0006406///mRNA export from nucleus","IPR036483///PWI domain superfamily+++IPR002483///PWI domain","[SRRM1_HUMAN|Reviewed]RecName: Full=Serine/arginine repetitive matrix protein 1; AltName: Full=SR-related nuclear matrix protein of 160 kDa; Short=SRm160; AltName: Full=Ser/Arg-related nuclear matrix protein;+++[A0A0S2Z4W1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 1 {ECO:0000313|EMBL:ALQ33970.1}; SubName: Full=Serine/arginine repetitive matrix 1, isoform CRA_a {ECO:0000313|EMBL:EAW95138.1}; Flags: Fragment;+++[A0A0S2Z4Z6_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix 1 isoform 2 {ECO:0000313|EMBL:ALQ33971.1}; Flags: Fragment;+++[A9Z1X7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000363510};+++[B7Z7U0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61739, highly similar to Serine/arginine repetitive matrix protein 1 {ECO:0000313|EMBL:BAH13726.1};+++[E9PCT1_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000391430};+++[M0QXG5_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000469151}; Flags: Fragment;+++[M0R088_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471084}; Flags: Fragment;+++[M0R1E7_HUMAN|Unreviewed]SubName: Full=Serine/arginine repetitive matrix protein 1 {ECO:0000313|Ensembl:ENSP00000471819};"]
[10251,"'SPRY3'",25,34,29.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function","GO:0061564///axon development+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0043407///negative regulation of MAP kinase activity+++GO:0046580///negative regulation of Ras protein signal transduction","IPR007875///Sprouty+++IPR030786///Protein sprouty homologue 3","[SPY3_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 3; Short=Spry-3;+++[Q6ZUP3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43494 fis, clone PEBLM2000170, moderately similar to Sprouty homolog 3 {ECO:0000313|EMBL:BAC86177.1};"]
[10252,"'SPRY1'",41,44,42.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0009966///regulation of signal transduction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0001656///metanephros development+++GO:0007275///multicellular organism development+++GO:0001759///organ induction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0034260///negative regulation of GTPase activity+++GO:0043407///negative regulation of MAP kinase activity+++GO:0001657///ureteric bud development+++GO:0008285///negative regulation of cell proliferation+++GO:0060940///epithelial to mesenchymal transition involved in cardiac fibroblast development+++GO:0060449///bud elongation involved in lung branching","IPR007875///Sprouty+++IPR030783///Protein sprouty homologue 1","[SPY1_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 1; Short=Spry-1;+++[D6REX7_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421622}; Flags: Fragment;+++[D6RHD2_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000421036}; Flags: Fragment;+++[D6RIE6_HUMAN|Unreviewed]SubName: Full=Protein sprouty homolog 1 {ECO:0000313|Ensembl:ENSP00000425946}; Flags: Fragment;+++[L8E896_HUMAN|Unreviewed]SubName: Full=Alternative protein SPRY1 {ECO:0000313|EMBL:CCQ43339.1};"]
[10253,"'SPRY2'",426,411,418.5,"04013///MAPK signaling pathway - fly+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015630///microtubule cytoskeleton+++GO:0042995///cell projection+++GO:0032587///ruffle membrane+++GO:0005634///nucleus","GO:0043539///protein serine/threonine kinase activator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0030291///protein serine/threonine kinase inhibitor activity","GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0034260///negative regulation of GTPase activity+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0060541///respiratory system development+++GO:0030324///lung development+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0016525///negative regulation of angiogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0031345///negative regulation of cell projection organization+++GO:0030335///positive regulation of cell migration+++GO:0060437///lung growth+++GO:0043407///negative regulation of MAP kinase activity+++GO:0007275///multicellular organism development+++GO:0045595///regulation of cell differentiation+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0009966///regulation of signal transduction+++GO:0000132///establishment of mitotic spindle orientation+++GO:0040037///negative regulation of fibroblast growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0008285///negative regulation of cell proliferation+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0060425///lung morphogenesis+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0045165///cell fate commitment+++GO:0060449///bud elongation involved in lung branching+++GO:0010628///positive regulation of gene expression+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0007605///sensory perception of sound+++GO:0042127///regulation of cell proliferation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway","IPR007875///Sprouty+++IPR030780///Protein sprouty homologue 2","[SPY2_HUMAN|Reviewed]RecName: Full=Protein sprouty homolog 2; Short=Spry-2;"]
[10254,"'STAM2'",413,499,456,"04630///Jak-STAT signaling pathway+++04144///Endocytosis",null,"M00408///ESCRT-0 complex",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0033565///ESCRT-0 complex+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome","GO:0005515///protein binding","GO:0016197///endosomal transport+++GO:0036258///multivesicular body assembly+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0061024///membrane organization+++GO:0016236///macroautophagy+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport","IPR002014///VHS domain+++IPR001452///SH3 domain+++IPR036028///SH3-like domain superfamily+++IPR003903///Ubiquitin interacting motif+++IPR035675///STAM2, SH3 domain+++IPR008942///ENTH/VHS","[STAM2_HUMAN|Reviewed]RecName: Full=Signal transducing adapter molecule 2; Short=STAM-2; AltName: Full=Hrs-binding protein;"]
[10256,"'CNKSR1'",14,9,11.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0030674///protein binding, bridging+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0007265///Ras protein signal transduction+++GO:0007266///Rho protein signal transduction","IPR036034///PDZ superfamily+++IPR017874///CRIC domain+++IPR001849///Pleckstrin homology domain+++IPR001660///Sterile alpha motif domain+++IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR011993///PH-like domain superfamily+++IPR001478///PDZ domain","[CNKR1_HUMAN|Reviewed]RecName: Full=Connector enhancer of kinase suppressor of ras 1; Short=Connector enhancer of KSR 1; AltName: Full=CNK homolog protein 1; Short=CNK1; Short=hCNK1; AltName: Full=Connector enhancer of KSR-like;+++[B4DL25_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60656, highly similar to Connector enhancer of kinase suppressor ofras 1 {ECO:0000313|EMBL:BAG59387.1};+++[B4DXN4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59272, highly similar to Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|EMBL:BAG63446.1};+++[E9PIE0_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000432057};+++[E9PS82_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000435880};+++[G3V160_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_a {ECO:0000313|EMBL:EAX07840.1}; SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000431817};+++[H0YDP5_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of ras 1 {ECO:0000313|Ensembl:ENSP00000434047}; Flags: Fragment;+++[Q53GM7_HUMAN|Unreviewed]SubName: Full=Connector enhancer of kinase suppressor of Ras 1 variant {ECO:0000313|EMBL:BAD96624.1}; SubName: Full=Connector enhancer of kinase suppressor of Ras 1, isoform CRA_b {ECO:0000313|EMBL:EAX07841.1}; Flags: Fragment;"]
[10257,"'ABCC4'",171,213,192,"02010///ABC transporters+++04976///Bile secretion+++04024///cAMP signaling pathway+++01523///Antifolate resistance",{"$nulls":3},"GO:0031088///platelet dense granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0015662///ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism+++GO:0043225///ATPase-coupled anion transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0016404///15-hydroxyprostaglandin dehydrogenase (NAD+) activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances","GO:0055085///transmembrane transport+++GO:0010243///response to organonitrogen compound+++GO:0060271///cilium assembly+++GO:0008150///biological_process+++GO:0002576///platelet degranulation+++GO:0010033///response to organic substance+++GO:0099131///ATP hydrolysis coupled ion transmembrane transport+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0042493///response to drug+++GO:0014070///response to organic cyclic compound+++GO:0032310///prostaglandin secretion+++GO:0099133///ATP hydrolysis coupled anion transmembrane transport+++GO:0055114///oxidation-reduction process","IPR003593///AAA+ ATPase domain+++IPR030240///Multidrug resistance-associated protein 4+++IPR036640///ABC transporter type 1, transmembrane domain superfamily+++IPR017871///ABC transporter, conserved site+++IPR003439///ABC transporter-like+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR011527///ABC transporter type 1, transmembrane domain","[MRP4_HUMAN|Reviewed]RecName: Full=Multidrug resistance-associated protein 4; AltName: Full=ATP-binding cassette sub-family C member 4; AltName: Full=MRP/cMOAT-related ABC transporter; AltName: Full=Multi-specific organic anion transporter B; Short=MOAT-B;+++[A0A2R8Y5Z3_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494938}; Flags: Fragment;+++[A0A2R8Y6V8_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000495513};+++[A0A2R8YDC1_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000494431}; Flags: Fragment;+++[A0A2R8YDG7_HUMAN|Unreviewed]SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493766};+++[A8K2Q2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77042, highly similar to Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4, mRNA {ECO:0000313|EMBL:BAF83006.1};+++[O75555_HUMAN|Unreviewed]SubName: Full=ABC transporter MOAT-B isoform {ECO:0000313|EMBL:AAC27077.1}; Flags: Fragment;+++[Q8IUA3_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 1 {ECO:0000313|EMBL:AAN08629.1}; SubName: Full=ATP-binding cassette subfamily C member 4 variant 3 {ECO:0000313|EMBL:AAN08630.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_a {ECO:0000313|EMBL:EAX08949.1};+++[Q8IWU1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette subfamily C member 4 variant 2 {ECO:0000313|EMBL:AAN08628.1}; SubName: Full=ATP-binding cassette, sub-family C (CFTR/MRP), member 4, isoform CRA_d {ECO:0000313|EMBL:EAX08952.1}; SubName: Full=Multidrug resistance-associated protein 4 {ECO:0000313|Ensembl:ENSP00000493861};"]
[1026,"'CDKN1A'",29823,32110,30966.5,"04928///Parathyroid hormone synthesis, secretion and action+++01522///Endocrine resistance+++05219///Bladder cancer+++04921///Oxytocin signaling pathway+++05203///Viral carcinogenesis+++05226///Gastric cancer+++05165///Human papillomavirus infection+++04066///HIF-1 signaling pathway+++05217///Basal cell carcinoma+++04068///FoxO signaling pathway+++04012///ErbB signaling pathway+++05215///Prostate cancer+++05225///Hepatocellular carcinoma+++04934///Cushing's syndrome+++05205///Proteoglycans in cancer+++05206///MicroRNAs in cancer+++05210///Colorectal cancer+++01524///Platinum drug resistance+++05218///Melanoma+++05166///HTLV-I infection+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++05160///Hepatitis C+++04115///p53 signaling pathway+++05220///Chronic myeloid leukemia+++04110///Cell cycle+++05212///Pancreatic cancer+++05169///Epstein-Barr virus infection+++05200///Pathways in cancer+++05161///Hepatitis B+++05223///Non-small cell lung cancer+++05214///Glioma+++04630///Jak-STAT signaling pathway+++05222///Small cell lung cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05211///Renal cell carcinoma+++04218///Cellular senescence+++05224///Breast cancer+++05163///Human cytomegalovirus infection+++05213///Endometrial cancer+++05216///Thyroid cancer","H00030///Cervical cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0070557///PCNA-p21 complex+++GO:0032991///protein-containing complex+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex","GO:0044877///protein-containing complex binding+++GO:0004860///protein kinase inhibitor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019912///cyclin-dependent protein kinase activating kinase activity+++GO:0016301///kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0030332///cyclin binding+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:0009636///response to toxic substance+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:0090398///cellular senescence+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010243///response to organonitrogen compound+++GO:0072331///signal transduction by p53 class mediator+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0071850///mitotic cell cycle arrest+++GO:0006974///cellular response to DNA damage stimulus+++GO:0055093///response to hyperoxia+++GO:0034198///cellular response to amino acid starvation+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0042326///negative regulation of phosphorylation+++GO:0010165///response to X-ray+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0010942///positive regulation of cell death+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0051412///response to corticosterone+++GO:0014070///response to organic cyclic compound+++GO:0010033///response to organic substance+++GO:0043066///negative regulation of apoptotic process+++GO:0042493///response to drug+++GO:0046685///response to arsenic-containing substance+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0090399///replicative senescence+++GO:0007265///Ras protein signal transduction+++GO:0090400///stress-induced premature senescence+++GO:0019221///cytokine-mediated signaling pathway+++GO:0034605///cellular response to heat+++GO:0045860///positive regulation of protein kinase activity+++GO:0071493///cellular response to UV-B+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0060574///intestinal epithelial cell maturation+++GO:0007050///cell cycle arrest+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0031668///cellular response to extracellular stimulus+++GO:0007346///regulation of mitotic cell cycle+++GO:0051384///response to glucocorticoid+++GO:0031100///animal organ regeneration+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0050821///protein stabilization+++GO:0007507///heart development+++GO:0030308///negative regulation of cell growth+++GO:0071479///cellular response to ionizing radiation+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle","IPR003175///Cyclin-dependent kinase inhibitor+++IPR029841///Cyclin-dependent kinase inhibitor 1, vertebrate","[CDN1A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1; AltName: Full=CDK-interacting protein 1; AltName: Full=Melanoma differentiation-associated protein 6; Short=MDA-6; AltName: Full=p21;+++[A0A024RCX5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1A (P21, Cip1), isoform CRA_a {ECO:0000313|EMBL:EAX03907.1};"]
[10260,"'DENND4A'",192.34,269,230.67,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0003677///DNA binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0006355///regulation of transcription, DNA-templated","IPR005113///uDENN domain+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR001194///cDENN domain+++IPR002885///Pentatricopeptide repeat+++IPR023341///MABP domain+++IPR005112///dDENN domain+++IPR037516///Tripartite DENN domain","[MYCPP_HUMAN|Reviewed]RecName: Full=C-myc promoter-binding protein; AltName: Full=DENN domain-containing protein 4A;+++[A0A0U1RR27_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000489304};+++[H3BSA0_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000456605}; Flags: Fragment;+++[H3BTW5_HUMAN|Unreviewed]SubName: Full=C-myc promoter-binding protein {ECO:0000313|Ensembl:ENSP00000457358}; Flags: Fragment;+++[Q05C90_HUMAN|Unreviewed]SubName: Full=DENND4A protein {ECO:0000313|EMBL:AAH28057.1}; Flags: Fragment;"]
[10262,"'SF3B4'",2511,2848,2679.5,"03040///Spliceosome","H01376///Acrofacial dysostosis","M00352///Spliceosome, U2-snRNP",null,"GO:0005912///adherens junction+++GO:0005913///cell-cell adherens junction+++GO:0045177///apical part of cell+++GO:0016607///nuclear speck+++GO:0005730///nucleolus+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0070160///tight junction+++GO:0030054///cell junction+++GO:0043296///apical junction complex+++GO:0044291///cell-cell contact zone+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0051015///actin filament binding+++GO:0050839///cell adhesion molecule binding+++GO:0003676///nucleic acid binding+++GO:0045296///cadherin binding+++GO:0017016///Ras GTPase binding+++GO:0003723///RNA binding","GO:0061951///establishment of protein localization to plasma membrane+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0034332///adherens junction organization+++GO:0060019///radial glial cell differentiation+++GO:0007267///cell-cell signaling+++GO:0060563///neuroepithelial cell differentiation+++GO:0043547///positive regulation of GTPase activity+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0090557///establishment of endothelial intestinal barrier+++GO:0007165///signal transduction+++GO:0007155///cell adhesion+++GO:0048872///homeostasis of number of cells+++GO:0034334///adherens junction maintenance+++GO:2000049///positive regulation of cell-cell adhesion mediated by cadherin+++GO:0070445///regulation of oligodendrocyte progenitor proliferation+++GO:0032880///regulation of protein localization+++GO:0030336///negative regulation of cell migration+++GO:0048854///brain morphogenesis+++GO:0021987///cerebral cortex development+++GO:1902414///protein localization to cell junction+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0008380///RNA splicing+++GO:0070830///bicellular tight junction assembly+++GO:0021537///telencephalon development","IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR034159///SF3B4, RNA recognition motif 2+++IPR000504///RNA recognition motif domain+++IPR034158///SF3B4, RNA recognition motif 1+++IPR035979///RNA-binding domain superfamily","[SF3B4_HUMAN|Reviewed]RecName: Full=Splicing factor 3B subunit 4; AltName: Full=Pre-mRNA-splicing factor SF3b 49 kDa subunit; AltName: Full=Spliceosome-associated protein 49; Short=SAP 49;+++[B3KUJ0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39996 fis, clone STOMA2002166, highly similar to Splicing factor 3B subunit 4 {ECO:0000313|EMBL:BAG53452.1};+++[Q5SZ64_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 4 {ECO:0000313|Ensembl:ENSP00000391114}; SubName: Full=Splicing factor 3b, subunit 4, 49kDa {ECO:0000313|EMBL:CAI12647.1}; Flags: Fragment;"]
[10263,"'CDK2AP2'",1418,1270,1344,{"$nulls":4},"GO:0005874///microtubule+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016301///kinase activity+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070507///regulation of microtubule cytoskeleton organization+++GO:2000035///regulation of stem cell division","IPR017266///Cyclin-dependent kinase 2-associated protein 1/2","[CDKA2_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein 2; Short=CDK2-associated protein 2; AltName: Full=DOC-1-related protein; Short=DOC-1R;+++[E9PKR4_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000431503};+++[E9PQJ3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 2-associated protein 2 {ECO:0000313|Ensembl:ENSP00000436213};+++[Q6IAV4_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase 2-associated protein {ECO:0000256|PIRNR:PIRNR037709};"]
[10265,"'IRX5'",12,4,8,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0005499///vitamin D binding+++GO:0003677///DNA binding","GO:0048468///cell development+++GO:0060040///retinal bipolar neuron differentiation+++GO:0010468///regulation of gene expression+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0042551///neuron maturation+++GO:0050896///response to stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007601///visual perception+++GO:0008406///gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0002027///regulation of heart rate","IPR009057///Homeobox-like domain superfamily+++IPR001356///Homeobox domain+++IPR017970///Homeobox, conserved site+++IPR003893///Iroquois-class homeodomain protein+++IPR008422///Homeobox KN domain","[IRX5_HUMAN|Reviewed]RecName: Full=Iroquois-class homeodomain protein IRX-5; AltName: Full=Homeodomain protein IRX-2A; AltName: Full=Homeodomain protein IRXB2; AltName: Full=Iroquois homeobox protein 5;+++[A2RRB5_HUMAN|Unreviewed]SubName: Full=IRX5 protein {ECO:0000313|EMBL:AAI31511.1}; SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000483446};+++[H0YML8_HUMAN|Unreviewed]SubName: Full=Iroquois-class homeodomain protein IRX-5 {ECO:0000313|Ensembl:ENSP00000453660};"]
[10266,"'RAMP2'",17,10,13.5,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0150057///amylin receptor complex 2+++GO:0005886///plasma membrane+++GO:0005905///clathrin-coated pit+++GO:0005887///integral component of plasma membrane+++GO:0005623///cell+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:1903143///adrenomedullin receptor complex+++GO:0043235///receptor complex","GO:0005515///protein binding+++GO:0001605///adrenomedullin receptor activity+++GO:0008565///protein transporter activity+++GO:0097643///amylin receptor activity+++GO:0015026///coreceptor activity+++GO:1990409///adrenomedullin binding","GO:0043116///negative regulation of vascular permeability+++GO:2001214///positive regulation of vasculogenesis+++GO:0002040///sprouting angiogenesis+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032570///response to progesterone+++GO:0031623///receptor internalization+++GO:0001666///response to hypoxia+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0001570///vasculogenesis+++GO:0006816///calcium ion transport+++GO:0070830///bicellular tight junction assembly+++GO:0008217///regulation of blood pressure+++GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0006886///intracellular protein transport+++GO:0032355///response to estradiol+++GO:0015031///protein transport+++GO:0097084///vascular smooth muscle cell development+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007507///heart development+++GO:0070831///basement membrane assembly+++GO:0097647///amylin receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0001525///angiogenesis+++GO:0072659///protein localization to plasma membrane+++GO:0034333///adherens junction assembly+++GO:0045766///positive regulation of angiogenesis+++GO:0007565///female pregnancy+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0010628///positive regulation of gene expression","IPR038126///RAMP domain superfamily+++IPR006985///Receptor activity modifying protein","[RAMP2_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 2; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 2; Short=CRLR activity-modifying protein 2; Flags: Precursor;+++[A0A024R1Z2_HUMAN|Unreviewed]SubName: Full=Receptor (Calcitonin) activity modifying protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW60878.1};+++[K7EKQ3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000465725};+++[K7ENJ8_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000466980}; Flags: Fragment;+++[K7EPN3_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 2 {ECO:0000313|Ensembl:ENSP00000467463};"]
[10267,"'RAMP1'",140,91,115.5,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:1990406///CGRP receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0150056///amylin receptor complex 1+++GO:0009986///cell surface+++GO:0005623///cell+++GO:0043235///receptor complex+++GO:0005886///plasma membrane","GO:0097643///amylin receptor activity+++GO:1990407///calcitonin gene-related peptide binding+++GO:0001635///calcitonin gene-related peptide receptor activity+++GO:0008565///protein transporter activity+++GO:0015026///coreceptor activity+++GO:0005515///protein binding","GO:0060050///positive regulation of protein glycosylation+++GO:0006886///intracellular protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0001525///angiogenesis+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0015031///protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0097647///amylin receptor signaling pathway+++GO:0031623///receptor internalization+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0006816///calcium ion transport+++GO:1990408///calcitonin gene-related peptide receptor signaling pathway","IPR006985///Receptor activity modifying protein+++IPR038126///RAMP domain superfamily","[RAMP1_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 1; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 1; Short=CRLR activity-modifying protein 1; Flags: Precursor;+++[E9PC20_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 1 {ECO:0000313|Ensembl:ENSP00000386720};+++[Q53SN3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY24219.1}; Flags: Fragment;+++[Q53T50_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RAMP1 {ECO:0000313|EMBL:AAY14674.1}; Flags: Fragment;"]
[10268,"'RAMP3'",9,6,7.5,"04270///Vascular smooth muscle contraction",{"$nulls":3},"GO:0005623///cell+++GO:0005764///lysosome+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0016021///integral component of membrane+++GO:1903143///adrenomedullin receptor complex+++GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0150058///amylin receptor complex 3","GO:0008565///protein transporter activity+++GO:0001605///adrenomedullin receptor activity+++GO:0001540///amyloid-beta binding+++GO:0015026///coreceptor activity+++GO:0097643///amylin receptor activity+++GO:0005515///protein binding","GO:0001921///positive regulation of receptor recycling+++GO:0006886///intracellular protein transport+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032870///cellular response to hormone stimulus+++GO:0071392///cellular response to estradiol stimulus+++GO:1990410///adrenomedullin receptor signaling pathway+++GO:0086103///G protein-coupled receptor signaling pathway involved in heart process+++GO:0010739///positive regulation of protein kinase A signaling+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0006816///calcium ion transport+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0031623///receptor internalization+++GO:0038041///cross-receptor inhibition within G protein-coupled receptor heterodimer+++GO:0010628///positive regulation of gene expression+++GO:0001525///angiogenesis+++GO:0097647///amylin receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1904645///response to amyloid-beta+++GO:0072659///protein localization to plasma membrane+++GO:0010942///positive regulation of cell death+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:1905665///positive regulation of calcium ion import across plasma membrane+++GO:0015031///protein transport","IPR038126///RAMP domain superfamily+++IPR006985///Receptor activity modifying protein","[RAMP3_HUMAN|Reviewed]RecName: Full=Receptor activity-modifying protein 3; AltName: Full=Calcitonin-receptor-like receptor activity-modifying protein 3; Short=CRLR activity-modifying protein 3; Flags: Precursor;+++[A4D2L1_HUMAN|Unreviewed]SubName: Full=Receptor (Calcitonin) activity modifying protein 3 {ECO:0000313|EMBL:EAL23743.1}; SubName: Full=Receptor (Calcitonin) activity modifying protein 3, isoform CRA_a {ECO:0000313|EMBL:EAW61048.1}; SubName: Full=cDNA, FLJ92137, Homo sapiens receptor (calcitonin) activity modifying protein 3(RAMP3), mRNA {ECO:0000313|EMBL:BAG34812.1};+++[J3KR56_HUMAN|Unreviewed]SubName: Full=Receptor activity-modifying protein 3 {ECO:0000313|Ensembl:ENSP00000418460};+++[L8E7U1_HUMAN|Unreviewed]SubName: Full=Alternative protein RAMP3 {ECO:0000313|EMBL:CCQ43340.1};+++[M5AMS3_HUMAN|Unreviewed]SubName: Full=Receptor (G protein-coupled) activity modifying protein 3 {ECO:0000313|EMBL:BAN10198.1}; Flags: Fragment;+++[M5AP16_HUMAN|Unreviewed]SubName: Full=Receptor (G protein-coupled) activity modifying protein 3 {ECO:0000313|EMBL:BAN10197.1}; Flags: Fragment;"]
[10269,"'ZMPSTE24'",663,704,683.5,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis","H00665///Mandibuloacral dysplasia+++H00663///Restrictive dermopathy",null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005635///nuclear envelope+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005637///nuclear inner membrane+++GO:0005634///nucleus+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0005789///endoplasmic reticulum membrane","GO:0004175///endopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005515///protein binding+++GO:0008235///metalloexopeptidase activity+++GO:0016787///hydrolase activity+++GO:0003690///double-stranded DNA binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0046872///metal ion binding","GO:0061337///cardiac conduction+++GO:0051276///chromosome organization+++GO:0060993///kidney morphogenesis+++GO:0003231///cardiac ventricle development+++GO:0003007///heart morphogenesis+++GO:0032006///regulation of TOR signaling+++GO:0032350///regulation of hormone metabolic process+++GO:0006998///nuclear envelope organization+++GO:1903025///regulation of RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0040014///regulation of multicellular organism growth+++GO:0003417///growth plate cartilage development+++GO:0010629///negative regulation of gene expression+++GO:1990164///histone H2A phosphorylation+++GO:0090239///regulation of histone H4 acetylation+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:1903522///regulation of blood circulation+++GO:0007628///adult walking behavior+++GO:1903463///regulation of mitotic cell cycle DNA replication+++GO:0050905///neuromuscular process+++GO:0008016///regulation of heart contraction+++GO:0044030///regulation of DNA methylation+++GO:1903799///negative regulation of production of miRNAs involved in gene silencing by miRNA+++GO:0006508///proteolysis+++GO:0070302///regulation of stress-activated protein kinase signaling cascade+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0030327///prenylated protein catabolic process+++GO:0071586///CAAX-box protein processing+++GO:0010506///regulation of autophagy+++GO:0001889///liver development+++GO:0010628///positive regulation of gene expression+++GO:0072423///response to DNA damage checkpoint signaling+++GO:0030500///regulation of bone mineralization+++GO:0044029///hypomethylation of CpG island+++GO:0048538///thymus development+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0043969///histone H2B acetylation+++GO:0035264///multicellular organism growth+++GO:0006281///DNA repair+++GO:0048145///regulation of fibroblast proliferation+++GO:0019216///regulation of lipid metabolic process+++GO:0006997///nucleus organization+++GO:0006325///chromatin organization+++GO:0007346///regulation of mitotic cell cycle+++GO:0050688///regulation of defense response to virus+++GO:0008544///epidermis development+++GO:0030282///bone mineralization+++GO:0043007///maintenance of rDNA+++GO:1990036///calcium ion import into sarcoplasmic reticulum+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001942///hair follicle development+++GO:0006925///inflammatory cell apoptotic process+++GO:0008340///determination of adult lifespan+++GO:0016485///protein processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0010906///regulation of glucose metabolic process+++GO:0048739///cardiac muscle fiber development+++GO:2000772///regulation of cellular senescence+++GO:0044255///cellular lipid metabolic process+++GO:0008360///regulation of cell shape+++GO:2000618///regulation of histone H4-K16 acetylation+++GO:0071480///cellular response to gamma radiation+++GO:0043979///histone H2B-K5 acetylation+++GO:2000730///regulation of termination of RNA polymerase I transcription","IPR027057///CAAX prenyl protease 1+++IPR001915///Peptidase M48+++IPR032456///CAAX prenyl protease 1, N-terminal","[FACE1_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 1 homolog; EC=3.4.24.84; AltName: Full=Farnesylated proteins-converting enzyme 1; Short=FACE-1; AltName: Full=Prenyl protein-specific endoprotease 1; AltName: Full=Zinc metalloproteinase Ste24 homolog;"]
[1027,"'CDKN1B'",156,124,140,"05226///Gastric cancer+++04068///FoxO signaling pathway+++05200///Pathways in cancer+++01522///Endocrine resistance+++05165///Human papillomavirus infection+++04933///AGE-RAGE signaling pathway in diabetic complications+++04934///Cushing's syndrome+++05206///MicroRNAs in cancer+++04066///HIF-1 signaling pathway+++05222///Small cell lung cancer+++05202///Transcriptional misregulation in cancer+++04151///PI3K-Akt signaling pathway+++04012///ErbB signaling pathway+++05220///Chronic myeloid leukemia+++05169///Epstein-Barr virus infection+++05215///Prostate cancer+++05161///Hepatitis B+++04110///Cell cycle+++05162///Measles+++05203///Viral carcinogenesis","H00024///Prostate cancer+++H00018///Gastric cancer+++H01431///Cushing's syndrome+++H01102///Pituitary adenomas+++H00247///Multiple endocrine neoplasia syndrome (MEN)",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0032991///protein-containing complex+++GO:0005768///endosome","GO:0051087///chaperone binding+++GO:0019903///protein phosphatase binding+++GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0005072///transforming growth factor beta receptor, cytoplasmic mediator activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019901///protein kinase binding+++GO:0030544///Hsp70 protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0044877///protein-containing complex binding","GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:0051271///negative regulation of cellular component movement+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0043434///response to peptide hormone+++GO:0046686///response to cadmium ion+++GO:0009749///response to glucose+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0048839///inner ear development+++GO:0033673///negative regulation of kinase activity+++GO:0071285///cellular response to lithium ion+++GO:0045930///negative regulation of mitotic cell cycle+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042326///negative regulation of phosphorylation+++GO:0071236///cellular response to antibiotic+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007049///cell cycle+++GO:0014070///response to organic cyclic compound+++GO:0008219///cell death+++GO:0010942///positive regulation of cell death+++GO:0001666///response to hypoxia+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0008284///positive regulation of cell proliferation+++GO:0001890///placenta development+++GO:1905179///negative regulation of cardiac muscle tissue regeneration+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0045787///positive regulation of cell cycle+++GO:0006813///potassium ion transport+++GO:0042493///response to drug+++GO:0045786///negative regulation of cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0031116///positive regulation of microtubule polymerization+++GO:0043200///response to amino acid+++GO:0071407///cellular response to organic cyclic compound+++GO:0007096///regulation of exit from mitosis+++GO:0042127///regulation of cell proliferation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest+++GO:0007507///heart development+++GO:1904706///negative regulation of vascular smooth muscle cell proliferation+++GO:0007219///Notch signaling pathway+++GO:0007605///sensory perception of sound+++GO:0071850///mitotic cell cycle arrest+++GO:0045732///positive regulation of protein catabolic process+++GO:0032355///response to estradiol","IPR003175///Cyclin-dependent kinase inhibitor+++IPR029843///Cyclin-dependent kinase inhibitor 1B","[CDN1B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1B; AltName: Full=Cyclin-dependent kinase inhibitor p27 {ECO:0000303|PubMed:28666995}; AltName: Full=p27Kip1 {ECO:0000303|PubMed:8033212};+++[A7KMP4_HUMAN|Unreviewed]SubName: Full=Truncated cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:ABS17636.1};+++[E7ES52_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000379629};+++[H7C2T1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|Ensembl:ENSP00000407597}; Flags: Fragment;+++[Q6I9V6_HUMAN|Unreviewed]SubName: Full=CDKN1B protein {ECO:0000313|EMBL:CAG33680.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:BAG70105.1}; SubName: Full=Cyclin-dependent kinase inhibitor 1B (P27, Kip1), isoform CRA_a {ECO:0000313|EMBL:EAW96275.1}; SubName: Full=cDNA, FLJ92816, Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1)(CDKN1B), mRNA {ECO:0000313|EMBL:BAG35368.1};+++[Q708J1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1B {ECO:0000313|EMBL:CAE82383.1}; Flags: Fragment;"]
[10270,"'AKAP8'",310,309,309.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0001939///female pronucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0000793///condensed chromosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0046872///metal ion binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0051059///NF-kappaB binding+++GO:0003723///RNA binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0042826///histone deacetylase binding+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0002376///immune system process+++GO:0000278///mitotic cell cycle+++GO:0031065///positive regulation of histone deacetylation+++GO:0044839///cell cycle G2/M phase transition+++GO:0033127///regulation of histone phosphorylation+++GO:0007165///signal transduction+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0007076///mitotic chromosome condensation+++GO:0071380///cellular response to prostaglandin E stimulus+++GO:0015031///protein transport+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response","IPR034736///Zinc finger C2H2 AKAP95-type+++IPR007071///A-kinase anchoring protein 95 (AKAP95)","[AKAP8_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 8; Short=AKAP-8; AltName: Full=A-kinase anchor protein 95 kDa; Short=AKAP 95;+++[M0QX51_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000468902};+++[M0QYL4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8 {ECO:0000313|Ensembl:ENSP00000469908}; Flags: Fragment;+++[Q8NE02_HUMAN|Unreviewed]SubName: Full=AKAP8 protein {ECO:0000313|EMBL:AAH37270.1};"]
[10272,"'FSTL3'",15979,13581,14780,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0030141///secretory granule+++GO:0005788///endoplasmic reticulum lumen+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0044306///neuron projection terminus+++GO:0005576///extracellular region","GO:0001968///fibronectin binding+++GO:0048185///activin binding+++GO:0005515///protein binding","GO:0030325///adrenal gland development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0044267///cellular protein metabolic process+++GO:0030324///lung development+++GO:0007283///spermatogenesis+++GO:0001822///kidney development+++GO:0043687///post-translational protein modification+++GO:0001503///ossification+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0008584///male gonad development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0071248///cellular response to metal ion+++GO:0090101///negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045671///negative regulation of osteoclast differentiation","IPR017878///TB domain+++IPR002350///Kazal domain+++IPR003645///Follistatin-like, N-terminal+++IPR036773///TGF-beta binding (TB) domain superfamily+++IPR036058///Kazal domain superfamily+++IPR015369///Follistatin/Osteonectin EGF domain","[FSTL3_HUMAN|Reviewed]RecName: Full=Follistatin-related protein 3; AltName: Full=Follistatin-like protein 3; AltName: Full=Follistatin-related gene protein; Flags: Precursor;+++[A0A024R1Y8_HUMAN|Unreviewed]SubName: Full=Follistatin-like 3 (Secreted glycoprotein), isoform CRA_a {ECO:0000313|EMBL:EAW61166.1};+++[A0A087WTD3_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000477770}; Flags: Fragment;+++[A0A087X1Q2_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000484376}; Flags: Fragment;+++[K7EM71_HUMAN|Unreviewed]SubName: Full=Follistatin-related protein 3 {ECO:0000313|Ensembl:ENSP00000466383};"]
[102723360,"'LOC102723360'",35.29,15.4,25.345,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding","GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0010468///regulation of gene expression","IPR019734///Tetratricopeptide repeat+++IPR029516///Histone demethylase UTY+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR011990///Tetratricopeptide-like helical domain superfamily","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102723475,"'KCNE1B'",0,3.02,1.51,{"$nulls":4},"GO:0008076///voltage-gated potassium channel complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005251///delayed rectifier potassium channel activity+++GO:0015459///potassium channel regulator activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding","GO:0006811///ion transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0097623///potassium ion export across plasma membrane+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086011///membrane repolarization during action potential+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport","IPR000369///Potassium channel, voltage-dependent, beta subunit, KCNE+++IPR005424///Potassium channel, voltage-dependent, beta subunit, KCNE1","[KCE1B_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000305};+++[A0A087WU88_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000478461};+++[A0A087WWU3_HUMAN|Unreviewed]SubName: Full=Potassium voltage-gated channel subfamily E member 1B {ECO:0000313|Ensembl:ENSP00000480511}; Flags: Fragment;"]
[102723502,"'LOC102723502'",17,7,12,{"$nulls":7},"IPR039497///CCDC144C-like, coiled-coil domain+++IPR002110///Ankyrin repeat+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily","[A0A0G2JMU2_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000479963};+++[A0A0G2JQB7_HUMAN|Unreviewed]SubName: Full=POTE ankyrin domain family member B3 {ECO:0000313|Ensembl:ENSP00000485729};"]
[102723534,"'LOC102723534'",5,6.52,5.76,"04120///Ubiquitin mediated proteolysis","H01911///Syndromic autosomal recessive mental retardation",null,null,"GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0032183///SUMO binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0007283///spermatogenesis+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006886///intracellular protein transport","IPR001199///Cytochrome b5-like heme/steroid binding domain+++IPR009091///Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II+++IPR037252///Mib/herc2 domain superfamily+++IPR021097///CPH domain+++IPR000569///HECT domain+++IPR036400///Cytochrome b5-like heme/steroid binding domain superfamily+++IPR006624///Beta-propeller repeat TECPR+++IPR037976///HERC2, APC10 domain+++IPR014722///Ribosomal protein L2, domain 2+++IPR000408///Regulator of chromosome condensation, RCC1+++IPR000433///Zinc finger, ZZ-type+++IPR035983///HECT, E3 ligase catalytic domain+++IPR008979///Galactose-binding-like domain superfamily+++IPR010606///Mib-herc2+++IPR004939///APC10/DOC domain","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[HERC2_DROME|diamond]RecName: Full=Probable E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_HUMAN|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000269|PubMed:20304803}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[HERC2_MOUSE|diamond]RecName: Full=E3 ubiquitin-protein ligase HERC2; EC=2.3.2.26 {ECO:0000250|UniProtKB:O95714}; AltName: Full=HECT domain and RCC1-like domain-containing protein 2; AltName: Full=HECT-type E3 ubiquitin transferase HERC2;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[102723547,"'CSAG2'",0,3,1.5,{"$nulls":6},"GO:0042493///response to drug",null,"[A0A1W2PPV0_HUMAN|Unreviewed]SubName: Full=Chondrosarcoma-associated gene 2/3 protein {ECO:0000313|Ensembl:ENSP00000491733};+++[A0A1W2PQG5_HUMAN|Unreviewed]SubName: Full=Chondrosarcoma-associated gene 2/3 protein {ECO:0000313|Ensembl:ENSP00000491720};+++[A0A1W2PR38_HUMAN|Unreviewed]SubName: Full=Chondrosarcoma-associated gene 2/3 protein {ECO:0000313|Ensembl:ENSP00000492298};+++[Q5ZEY7_HUMAN|Unreviewed]SubName: Full=Taxol resistance associated gene 3 {ECO:0000313|EMBL:CAH59758.2}; Flags: Fragment;"]
[102723553,"'SMIM11B'",119.08,101.73,110.405,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"IPR028023///Small integral membrane protein 11A","[SI11A_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11A {ECO:0000312|HGNC:HGNC:1293};+++[SI11B_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 11B {ECO:0000312|HGNC:HGNC:51846};"]
[102723555,"'SPDYE16'",0,1.03,0.515,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","IPR020984///Cell cycle regulatory protein Speedy","[SPD16_HUMAN|Reviewed]RecName: Full=Putative speedy protein E16 {ECO:0000305};+++[A0A0J9YVZ0_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487736};+++[A0A0J9YW45_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000487806};+++[A0A0J9YWM7_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488034};+++[A0A0J9YYB4_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488772};+++[A0A0J9YYF2_HUMAN|Unreviewed]SubName: Full=Putative speedy protein E16 {ECO:0000313|Ensembl:ENSP00000488825};"]
[102723623,"'LOC102723623'",0.26,2,1.13,{"$nulls":7},"IPR026737///Golgin subfamily A member 6-like","[GG6L1_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 1;+++[GG6L2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 2;+++[GG6L6_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 6;+++[GG6L7_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 7 {ECO:0000305};+++[GG6LV_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 22 {ECO:0000305};"]
[102723713,"'LOC102723713'",1,0,0.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm",{"$nulls":3},"[T53G3_HUMAN|Reviewed]RecName: Full=TP53-target gene 3 protein; AltName: Full=TP53-inducible gene 3 protein;"]
[102723722,"'LOC102723722'",0,0.27,0.135,"01522///Endocrine resistance+++00980///Metabolism of xenobiotics by cytochrome P450+++00982///Drug metabolism - cytochrome P450+++04726///Serotonergic synapse","H01171///Poor drug metabolism (PM)",null,"R09421///4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP++++R08343///Citalopram <=> Demethylcitalopram+++R08345///Demethylcitalopram <=> Didemethylcitalopram+++R08344///Citalopram <=> Citalopram N-oxide+++R03697///Morphine + [Oxidized NADPH---hemoprotein reductase] + Formaldehyde + H2O <=> Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen+++R08270///N-Desmethyltamoxifen + NADPH + Oxygen + H+ <=> Endoxifen + NADP+ + H2O+++R08267///Tamoxifen + NADPH + Oxygen + H+ <=> Hydroxytamoxifen + NADP+ + H2O","GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005783///endoplasmic reticulum","GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0005506///iron ion binding+++GO:0004497///monooxygenase activity+++GO:0046872///metal ion binding+++GO:0008144///drug binding+++GO:0043023///ribosomal large subunit binding+++GO:0016491///oxidoreductase activity+++GO:0016887///ATPase activity+++GO:0008395///steroid hydroxylase activity+++GO:0005524///ATP binding+++GO:0043022///ribosome binding+++GO:0070330///aromatase activity+++GO:0005525///GTP binding+++GO:0020037///heme binding","GO:0090350///negative regulation of cellular organofluorine metabolic process+++GO:0017144///drug metabolic process+++GO:0016098///monoterpenoid metabolic process+++GO:0042737///drug catabolic process+++GO:0046034///ATP metabolic process+++GO:0051100///negative regulation of binding+++GO:0009820///alkaloid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006805///xenobiotic metabolic process+++GO:0019369///arachidonic acid metabolic process+++GO:0009804///coumarin metabolic process+++GO:0042738///exogenous drug catabolic process+++GO:0046483///heterocycle metabolic process+++GO:0033076///isoquinoline alkaloid metabolic process+++GO:0070989///oxidative demethylation+++GO:0009822///alkaloid catabolic process+++GO:0008202///steroid metabolic process+++GO:0042759///long-chain fatty acid biosynthetic process","IPR006073///GTP binding domain+++IPR001128///Cytochrome P450+++IPR002401///Cytochrome P450, E-class, group I+++IPR013029///YchF, C-terminal domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR017972///Cytochrome P450, conserved site+++IPR031167///OBG-type guanine nucleotide-binding (G) domain+++IPR008069///Cytochrome P450, E-class, group I, CYP2D-like+++IPR012675///Beta-grasp domain superfamily+++IPR023192///TGS-like domain superfamily+++IPR012676///TGS-like+++IPR004396///Ribosome-binding ATPase YchF/Obg-like ATPase 1+++IPR036396///Cytochrome P450 superfamily","[CP2D6_HUMAN|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000269|PubMed:21576599}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000305|PubMed:21576599}; AltName: Full=Cytochrome P450-DB1; AltName: Full=Debrisoquine 4-hydroxylase;+++[CP2D6_PANPA|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D6_PANTR|diamond]RecName: Full=Cytochrome P450 2D6; EC=1.14.14.1 {ECO:0000250|UniProtKB:P10635}; AltName: Full=CYPIID6; AltName: Full=Cholesterol 25-hydroxylase {ECO:0000250|UniProtKB:P10635};+++[CP2D7_HUMAN|diamond]RecName: Full=Putative cytochrome P450 2D7 {ECO:0000305}; EC=1.14.14.1 {ECO:0000269|PubMed:15051713};+++[CP2DH_MACFA|diamond]RecName: Full=Cytochrome P450 2D17; EC=1.14.14.1; AltName: Full=CYPIID17;+++[OLA1_BOVIN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_HUMAN|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=DNA damage-regulated overexpressed in cancer 45; Short=DOC45; AltName: Full=GTP-binding protein 9;+++[OLA1_MOUSE|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167}; AltName: Full=GTP-binding protein 9;+++[OLA1_PONAB|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};+++[OLA1_RAT|diamond]RecName: Full=Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167};"]
[102723728,"'LOC102723728'",3402.9,1866.08,2634.49,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding",null,"IPR013784///Carbohydrate-binding-like fold+++IPR008969///Carboxypeptidase-like, regulatory domain superfamily","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;"]
[102723750,"'LOC102723750'",0,1,0.5,{"$nulls":8},"[K7DZX1_MONDO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMODP00000039072};+++[K7FQE9_PELSI|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPSIP00000010259};"]
[102723859,"'TBC1D3E'",96.65,95.2,95.925,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0006886///intracellular protein transport+++GO:0090630///activation of GTPase activity","IPR000195///Rab-GTPase-TBC domain+++IPR035969///Rab-GTPase-TBC domain superfamily","[TBC3E_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 3E {ECO:0000312|HGNC:HGNC:27071};"]
[102723996,"'LOC102723996'",26.9,44.75,35.825,"04672///Intestinal immune network for IgA production+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0009986///cell surface+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane","GO:0042802///identical protein binding+++GO:0005102///signaling receptor binding","GO:0007166///cell surface receptor signaling pathway+++GO:0007165///signal transduction+++GO:0042102///positive regulation of T cell proliferation+++GO:0031295///T cell costimulation+++GO:0071222///cellular response to lipopolysaccharide+++GO:0042130///negative regulation of T cell proliferation+++GO:0006955///immune response","IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013162///CD80-like, immunoglobulin C2-set+++IPR003599///Immunoglobulin subtype+++IPR013106///Immunoglobulin V-set domain+++IPR007110///Immunoglobulin-like domain","[ICOSL_HUMAN|Reviewed]RecName: Full=ICOS ligand; AltName: Full=B7 homolog 2; Short=B7-H2; AltName: Full=B7-like protein Gl50; AltName: Full=B7-related protein 1; Short=B7RP-1; AltName: CD_antigen=CD275; Flags: Precursor;+++[A0A087X1L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000484302};+++[A0A096LPE5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485557};+++[A0N0L8_HUMAN|Unreviewed]SubName: Full=Inducible T-cell co-stimulator ligand {ECO:0000313|EMBL:ABK41909.1}; SubName: Full=Inducible T-cell co-stimulator ligand, isoform CRA_c {ECO:0000313|EMBL:EAX09448.1}; SubName: Full=cDNA FLJ77643, highly similar to Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAF82881.1}; SubName: Full=cDNA, FLJ95137, Homo sapiens B7-like protein (B7H2), mRNA {ECO:0000313|EMBL:BAG36999.1};"]
[102724023,"'GATD3B'",277.67,240.29,258.98,{"$nulls":4},"GO:0005739///mitochondrion",null,null,"IPR029062///Class I glutamine amidotransferase-like","[GAL3B_HUMAN|Reviewed]RecName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial; AltName: Full=Keio novel protein-I {ECO:0000303|PubMed:8753807}; Short=KNP-I {ECO:0000303|PubMed:8753807}; AltName: Full=Protein GT335 {ECO:0000303|PubMed:8975701}; AltName: Full=Protein HES1 {ECO:0000303|PubMed:9150728}; Flags: Precursor;+++[A0A096LNH5_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000483086};+++[A0A096LNJ1_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485058}; Flags: Fragment;+++[A0A096LP12_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial {ECO:0000313|Ensembl:ENSP00000374340}; SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485335}; Flags: Fragment;+++[A0A096LP57_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485404};+++[A0A096LP73_HUMAN|Unreviewed]SubName: Full=Glutamine amidotransferase-like class 1 domain-containing protein 3B, mitochondrial {ECO:0000313|Ensembl:ENSP00000485439}; Flags: Fragment;+++[A0A0B4J2H4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485300};"]
[102724135,"'LOC102724135'",13.74,15.31,14.525,{"$nulls":4},"GO:0005794///Golgi apparatus","GO:0004691///cAMP-dependent protein kinase activity","GO:0035023///regulation of Rho protein signal transduction","IPR024858///Golgin subfamily A","[GOG6B_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6B;+++[GOG6C_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6C;+++[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8F_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 8F/8G;+++[GOG8S_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8S {ECO:0000305};"]
[102724159,"'LOC102724159'",114.22,128.61,121.415,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0032040///small-subunit processome","GO:0030515///snoRNA binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","IPR017986///WD40-repeat-containing domain+++IPR020472///G-protein beta WD-40 repeat+++IPR007148///Small-subunit processome, Utp12+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR001680///WD40 repeat+++IPR011047///Quinoprotein alcohol dehydrogenase-like superfamily+++IPR027145///Periodic tryptophan protein 2+++IPR019775///WD40 repeat, conserved site","[PWP2_HUMAN|Reviewed]RecName: Full=Periodic tryptophan protein 2 homolog;+++[A0A0B4J2E5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000482107};+++[A0A0J9YX21_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000488213}; Flags: Fragment;"]
[102724197,"'LOC102724197'",1.27,2,1.635,"01100///Metabolic pathways+++00460///Cyanoamino acid metabolism+++00430///Taurine and hypotaurine metabolism+++00590///Arachidonic acid metabolism+++00480///Glutathione metabolism",null,null,"R09875///leukotriene-C4 hydrolase Leukotriene C4 + H2O <=> Leukotriene D4 + L-Glutamate+++R01687///(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase (5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine+++R00494///glutathione gamma-glutamylaminopeptidase Glutathione + H2O <=> Cys-Gly + L-Glutamate+++R03970///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase 3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O+++R03971///gamma-glutamyl-beta-aminopropiononitrile amidohydrolase 3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O+++R01262///glutathione:L-amino-acid 5-glutamyltransferase Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid+++R03916///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate","GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0036374///glutathione hydrolase activity+++GO:0000048///peptidyltransferase activity","GO:0006749///glutathione metabolic process+++GO:0019344///cysteine biosynthetic process+++GO:0031638///zymogen activation+++GO:0006751///glutathione catabolic process+++GO:0002682///regulation of immune system process+++GO:0006520///cellular amino acid metabolic process+++GO:0006412///translation+++GO:0031179///peptide modification+++GO:1901750///leukotriene D4 biosynthetic process+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0050727///regulation of inflammatory response+++GO:0032355///response to estradiol+++GO:0034612///response to tumor necrosis factor+++GO:0032496///response to lipopolysaccharide+++GO:0006536///glutamate metabolic process","IPR029055///Nucleophile aminohydrolases, N-terminal+++IPR000101///Gamma-glutamyltranspeptidase","[GGT2_HUMAN|Reviewed]RecName: Full=Inactive glutathione hydrolase 2; AltName: Full=Gamma-glutamyltransferase 2; AltName: Full=Inactive gamma-glutamyltranspeptidase 2; Short=GGT 2; Flags: Precursor;+++[B5MCK8_HUMAN|Unreviewed]SubName: Full=Inactive glutathione hydrolase 2 {ECO:0000313|Ensembl:ENSP00000385601};"]
[102724200,"'LOC102724200'",14.51,21.35,17.93,{"$nulls":4},"GO:1990071///TRAPPII protein complex+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0034498///early endosome to Golgi transport","IPR022233///TRAPP II complex, TRAPPC10","[A0A096LPH7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000485615}; Flags: Fragment;"]
[102724219,"'LOC102724219'",89.11,113.59,101.35,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation","IPR013544///Domain of unknown function DUF1725+++IPR005135///Endonuclease/exonuclease/phosphatase+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR000477///Reverse transcriptase domain","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724250,"'LOC102724250'",203.24,266.74,234.99,{"$nulls":4},"GO:0005737///cytoplasm",null,null,"IPR010630///Neuroblastoma breakpoint family (NBPF) domain","[NBPF1_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 1;+++[NBPF8_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 8;+++[NBPF9_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 9;+++[NBPFA_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 10;+++[NBPFB_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 11 {ECO:0000305}; AltName: Full=Neuroblastoma breakpoint family member 24 {ECO:0000312|HGNC:HGNC:31993};+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[NBPFE_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 14;+++[NBPFF_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 15 {ECO:0000312|HGNC:HGNC:28791}; AltName: Full=Neuroblastoma breakpoint family member 16 {ECO:0000312|HGNC:HGNC:28791};+++[NBPFJ_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 19 {ECO:0000312|HGNC:HGNC:31999};"]
[102724279,"'LINC01835'",7,6,6.5,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"IPR018378///C-type lectin, conserved site+++IPR016186///C-type lectin-like/link domain superfamily+++IPR001304///C-type lectin-like+++IPR016187///C-type lectin fold","[CLC4G_HUMAN|diamond]RecName: Full=C-type lectin domain family 4 member G; AltName: Full=Liver and lymph node sinusoidal endothelial cell C-type lectin {ECO:0000303|PubMed:14711836}; Short=LSECtin {ECO:0000303|PubMed:14711836};+++[COL12_CHICK|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin-3; Short=CL-3; Short=cCL-3;+++[COL12_HUMAN|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; Short=hCL-P1; AltName: Full=Nurse cell scavenger receptor 2; AltName: Full=Scavenger receptor class A member 4; AltName: Full=Scavenger receptor with C-type lectin;+++[COL12_MOUSE|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; AltName: Full=Scavenger receptor with C-type lectin;+++[COL12_RAT|diamond]RecName: Full=Collectin-12; AltName: Full=Collectin placenta protein 1; Short=CL-P1; AltName: Full=Nurse cell scavenger receptor 2;"]
[102724378,"'LOC102724378'",11,10,10.5]
[102724428,"'SIK1B'",6233.37,7308.8,6771.085,"04922///Glucagon signaling pathway","H00606///Early infantile epileptic encephalopathy+++H01819///Early myoclonic encephalopathy",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0032870///cellular response to hormone stimulus","IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR017441///Protein kinase, ATP binding site+++IPR015940///Ubiquitin-associated domain+++IPR034672///Salt-Inducible kinase, catalytic domain+++IPR017090///Serine/threonine-protein kinase, SIK1/2+++IPR011009///Protein kinase-like domain superfamily","[SIK1B_HUMAN|Reviewed]RecName: Full=Probable serine/threonine-protein kinase SIK1B {ECO:0000305}; EC=2.7.11.1 {ECO:0000250|UniProtKB:P57059, ECO:0000255|PROSITE-ProRule:PRU00159}; AltName: Full=Salt-inducible kinase 1B {ECO:0000305};+++[SIK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase SIK1; EC=2.7.11.1 {ECO:0000269|PubMed:14976552, ECO:0000269|PubMed:18348280}; AltName: Full=Salt-inducible kinase 1; Short=SIK-1; AltName: Full=Serine/threonine-protein kinase SNF1-like kinase 1; Short=Serine/threonine-protein kinase SNF1LK;"]
[102724474,"'LOC102724474'",3,6,4.5,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005796///Golgi lumen+++GO:0005886///plasma membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0031233///intrinsic component of external side of plasma membrane","GO:0004252///serine-type endopeptidase activity+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0051897///positive regulation of protein kinase B signaling+++GO:0030335///positive regulation of cell migration+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007596///blood coagulation+++GO:0007598///blood coagulation, extrinsic pathway","IPR000742///EGF-like domain+++IPR017857///Coagulation factor-like, Gla domain superfamily+++IPR013032///EGF-like, conserved site+++IPR009003///Peptidase S1, PA clan+++IPR012224///Peptidase S1A, coagulation factor VII/IX/X/C/Z+++IPR035972///Gamma-carboxyglutamic acid-rich (GLA) domain superfamily+++IPR018114///Serine proteases, trypsin family, histidine active site+++IPR000294///Gamma-carboxyglutamic acid-rich (GLA) domain+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR001314///Peptidase S1A, chymotrypsin family+++IPR018097///EGF-like calcium-binding, conserved site+++IPR001254///Serine proteases, trypsin domain+++IPR033116///Serine proteases, trypsin family, serine active site+++IPR001881///EGF-like calcium-binding domain","[FA10_BOVIN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_HUMAN|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; AltName: Full=Stuart-Prower factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_MOUSE|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RABIT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;+++[FA10_RAT|diamond]RecName: Full=Coagulation factor X; EC=3.4.21.6; AltName: Full=Stuart factor; Contains: RecName: Full=Factor X light chain; Contains: RecName: Full=Factor X heavy chain; Contains: RecName: Full=Activated factor Xa heavy chain; Flags: Precursor;"]
[102724488,"'LOC102724488'",47.43,54.05,50.74,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0019905///syntaxin binding+++GO:0005544///calcium-dependent phospholipid binding+++GO:0005509///calcium ion binding+++GO:0030276///clathrin binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0006906///vesicle fusion+++GO:0017158///regulation of calcium ion-dependent exocytosis","IPR035892///C2 domain superfamily+++IPR000008///C2 domain+++IPR030539///Synaptotagmin-15","[SYT15_HUMAN|Reviewed]RecName: Full=Synaptotagmin-15; AltName: Full=Chr10Syt; AltName: Full=Synaptotagmin XV; Short=SytXV;+++[A0A096LNH4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000478933}; Flags: Fragment;+++[X6R8R1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin-15 {ECO:0000313|Ensembl:ENSP00000363443};"]
[102724560,"'CBSL'",201.76,283.17,242.465,"01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00270///Cysteine and methionine metabolism+++00260///Glycine, serine and threonine metabolism+++01230///Biosynthesis of amino acids","H00183///Homocystinuria","M00035///Methionine degradation+++M00338///Cysteine biosynthesis, homocysteine + serine => cysteine","R01290///L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming)   L-Serine + L-Homocysteine <=> L-Cystathionine + H2O+++R04942///L-Serine hydro-lyase (adding homocysteine)   L-Serine + Selenohomocysteine <=> L-Selenocystathionine + H2O+++R00891///L-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)   L-Serine + Hydrogen sulfide <=> L-Cysteine + H2O","GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016829///lyase activity+++GO:0004122///cystathionine beta-synthase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0004124///cysteine synthase activity+++GO:0020037///heme binding","GO:0008652///cellular amino acid biosynthetic process+++GO:0019344///cysteine biosynthetic process+++GO:0006535///cysteine biosynthetic process from serine+++GO:0019346///transsulfuration+++GO:0019343///cysteine biosynthetic process via cystathionine+++GO:0070814///hydrogen sulfide biosynthetic process+++GO:0050667///homocysteine metabolic process","IPR000644///CBS domain+++IPR036052///Tryptophan synthase beta subunit-like PLP-dependent enzyme+++IPR001216///Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site+++IPR001926///Pyridoxal-phosphate dependent enzyme+++IPR005857///Cystathionine beta-synthase","[CBS_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase {ECO:0000305}; EC=4.2.1.22 {ECO:0000269|PubMed:20506325, ECO:0000269|PubMed:23974653, ECO:0000269|PubMed:23981774, ECO:0000269|PubMed:25044645}; AltName: Full=Beta-thionase; AltName: Full=Serine sulfhydrase;+++[CBSL_HUMAN|Reviewed]RecName: Full=Cystathionine beta-synthase-like protein {ECO:0000305}; EC=4.2.1.22 {ECO:0000250|UniProtKB:P35520}; AltName: Full=Beta-thionase {ECO:0000250|UniProtKB:P35520}; AltName: Full=Serine sulfhydrase {ECO:0000250|UniProtKB:P35520};"]
[102724594,"'U2AF1L5'",31.96,66.98,49.47,"05131///Shigellosis+++03040///Spliceosome","H01481///Myelodysplastic syndrome (MDS)",null,null,"GO:0089701///U2AF+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex","GO:0046872///metal ion binding+++GO:0030628///pre-mRNA 3'-splice site binding+++GO:0003723///RNA binding+++GO:0050733///RS domain binding+++GO:0003676///nucleic acid binding","GO:0000398///mRNA splicing, via spliceosome","IPR000571///Zinc finger, CCCH-type+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR009145///U2 auxiliary factor small subunit+++IPR003954///RNA recognition motif domain, eukaryote+++IPR000504///RNA recognition motif domain","[U2AF1_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit; AltName: Full=U2 auxiliary factor 35 kDa subunit; AltName: Full=U2 small nuclear RNA auxiliary factor 1; AltName: Full=U2 snRNP auxiliary factor small subunit;+++[U2AF5_HUMAN|Reviewed]RecName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000305}; AltName: Full=U2 small nuclear RNA auxiliary factor 1-like protein 5 {ECO:0000312|HGNC:HGNC:51830};+++[A0A1B0GW87_HUMAN|Unreviewed]SubName: Full=Splicing factor U2AF 35 kDa subunit-like protein {ECO:0000313|Ensembl:ENSP00000490825};"]
[102724642,"'LOC102724642'",0.92,0,0.46,"04111///Cell cycle - yeast+++04120///Ubiquitin mediated proteolysis+++04110///Cell cycle+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04914///Progesterone-mediated oocyte maturation+++04114///Oocyte meiosis",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex+++GO:0005634///nucleus",null,"GO:0007049///cell cycle+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0051301///cell division","IPR002015///Proteasome/cyclosome repeat+++IPR024990///Anaphase-promoting complex subunit 1","[APC1_CAEEL|diamond]RecName: Full=Anaphase-promoting complex subunit 1 {ECO:0000250|UniProtKB:Q9H1A4}; Short=APC1 {ECO:0000250|UniProtKB:Q9H1A4}; AltName: Full=Metaphase-to-anaphase transition protein 2 {ECO:0000312|WormBase:W10C6.1};+++[APC1_DICDI|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1;+++[APC1_HUMAN|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1; AltName: Full=Cyclosome subunit 1; AltName: Full=Mitotic checkpoint regulator; AltName: Full=Testis-specific gene 24 protein;+++[APC1_MOUSE|diamond]RecName: Full=Anaphase-promoting complex subunit 1; Short=APC1; AltName: Full=Cyclosome subunit 1; AltName: Full=Mitotic checkpoint regulator; AltName: Full=Testis-specific gene 24 protein;"]
[102724646,"'LOC102724646'",1,1,1,{"$nulls":4},"GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005623///cell+++GO:0005829///cytosol+++GO:0045121///membrane raft","GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0046872///metal ion binding+++GO:0004713///protein tyrosine kinase activity+++GO:0015631///tubulin binding+++GO:0005102///signaling receptor binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding","GO:0008360///regulation of cell shape+++GO:0042981///regulation of apoptotic process+++GO:0030900///forebrain development+++GO:0042127///regulation of cell proliferation+++GO:0007417///central nervous system development+++GO:0050852///T cell receptor signaling pathway+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0001764///neuron migration+++GO:0045087///innate immune response+++GO:0016477///cell migration+++GO:0030154///cell differentiation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0042110///T cell activation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway","IPR008266///Tyrosine-protein kinase, active site+++IPR036860///SH2 domain superfamily+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain+++IPR035750///Fyn/Yrk, SH3 domain+++IPR036028///SH3-like domain superfamily+++IPR020635///Tyrosine-protein kinase, catalytic domain+++IPR001452///SH3 domain+++IPR017441///Protein kinase, ATP binding site+++IPR000980///SH2 domain","[FYN_BOVIN|diamond]RecName: Full=Tyrosine-protein kinase Fyn; EC=2.7.10.2; AltName: Full=Proto-oncogene c-Fyn; AltName: Full=p59-Fyn;+++[FYN_CHICK|diamond]RecName: Full=Tyrosine-protein kinase Fyn; EC=2.7.10.2; AltName: Full=Proto-oncogene c-Fyn; AltName: Full=p59-Fyn;+++[FYN_HUMAN|diamond]RecName: Full=Tyrosine-protein kinase Fyn; EC=2.7.10.2; AltName: Full=Proto-oncogene Syn; AltName: Full=Proto-oncogene c-Fyn; AltName: Full=Src-like kinase; Short=SLK; AltName: Full=p59-Fyn;+++[FYN_PIG|diamond]RecName: Full=Tyrosine-protein kinase Fyn; EC=2.7.10.2; AltName: Full=Proto-oncogene c-Fyn; AltName: Full=p59-Fyn;+++[FYN_RAT|diamond]RecName: Full=Tyrosine-protein kinase Fyn; EC=2.7.10.2; AltName: Full=Proto-oncogene c-Fyn; AltName: Full=p59-Fyn;"]
[102724652,"'CRYAA2'",2,1,1.5,"04141///Protein processing in endoplasmic reticulum","H01202///Cataract",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005212///structural constituent of eye lens+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050896///response to stimulus+++GO:0051260///protein homooligomerization+++GO:0032387///negative regulation of intracellular transport+++GO:0042026///protein refolding+++GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization+++GO:0007601///visual perception","IPR031107///Small heat shock protein HSP20+++IPR008978///HSP20-like chaperone+++IPR002068///Alpha crystallin/Hsp20 domain+++IPR012274///Alpha-crystallin, subunit A+++IPR003090///Alpha-crystallin, N-terminal+++IPR001436///Alpha crystallin/Heat shock protein","[CRYA2_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A2 chain {ECO:0000305}; Contains: RecName: Full=Alpha-crystallin A2(1-172); Contains: RecName: Full=Alpha-crystallin A2(1-168); Contains: RecName: Full=Alpha-crystallin A2(1-162);+++[CRYAA_HUMAN|Reviewed]RecName: Full=Alpha-crystallin A chain; AltName: Full=Heat shock protein beta-4; Short=HspB4; Contains: RecName: Full=Alpha-crystallin A(1-172); Contains: RecName: Full=Alpha-crystallin A(1-168); Contains: RecName: Full=Alpha-crystallin A(1-162);+++[A0A096LPJ9_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A2 chain {ECO:0000313|Ensembl:ENSP00000485653};+++[A0A140G952_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63592.1}; Flags: Fragment;+++[A0A140G954_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63594.1}; Flags: Fragment;+++[A0A140G955_HUMAN|Unreviewed]SubName: Full=Alpha crystallin A chain {ECO:0000313|EMBL:AMM63595.1}; Flags: Fragment;+++[E7EWH7_HUMAN|Unreviewed]SubName: Full=Alpha-crystallin A chain {ECO:0000313|Ensembl:ENSP00000381201};+++[Q71V83_HUMAN|Unreviewed]SubName: Full=Alpha-A-crystallin {ECO:0000313|EMBL:AAB99912.1}; Flags: Fragment;"]
[102724720,"'LOC102724720'",1,0,0.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003839///gamma-glutamylcyclotransferase activity+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0001836///release of cytochrome c from mitochondria+++GO:0006750///glutathione biosynthetic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","IPR017939///Gamma-glutamylcyclotransferase+++IPR000477///Reverse transcriptase domain+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR019351///Protein of unknown function DUF2039+++IPR013544///Domain of unknown function DUF1725+++IPR036568///Gamma-glutamyl cyclotransferase-like superfamily+++IPR005135///Endonuclease/exonuclease/phosphatase+++IPR013024///Gamma-glutamyl cyclotransferase-like","[CFA61_MOUSE|diamond]RecName: Full=Cilia- and flagella-associated protein 61 {ECO:0000312|MGI:MGI:1926024};+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GGCT_HUMAN|diamond]RecName: Full=Gamma-glutamylcyclotransferase; EC=4.3.2.9; AltName: Full=Cytochrome c-releasing factor 21;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[102724751,"'LOC102724751'",78.22,52.65,65.435,"05200///Pathways in cancer+++05220///Chronic myeloid leukemia",{"$nulls":3},"GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0099092///postsynaptic density, intracellular component+++GO:0032991///protein-containing complex+++GO:0070062///extracellular exosome+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0045211///postsynaptic membrane","GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0050885///neuromuscular process controlling balance+++GO:0035023///regulation of Rho protein signal transduction+++GO:0071222///cellular response to lipopolysaccharide+++GO:0043314///negative regulation of neutrophil degranulation+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0050804///modulation of chemical synaptic transmission+++GO:0046777///protein autophosphorylation+++GO:0042472///inner ear morphogenesis+++GO:0060268///negative regulation of respiratory burst+++GO:0002692///negative regulation of cellular extravasation+++GO:0065002///intracellular protein transmembrane transport+++GO:0050728///negative regulation of inflammatory response+++GO:0060313///negative regulation of blood vessel remodeling+++GO:0043547///positive regulation of GTPase activity+++GO:0050766///positive regulation of phagocytosis+++GO:0006468///protein phosphorylation+++GO:0030036///actin cytoskeleton organization+++GO:0060216///definitive hemopoiesis+++GO:0051726///regulation of cell cycle+++GO:0043114///regulation of vascular permeability+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:0035556///intracellular signal transduction+++GO:0003014///renal system process+++GO:0048872///homeostasis of number of cells+++GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007420///brain development+++GO:0051171///regulation of nitrogen compound metabolic process","IPR000219///Dbl homology (DH) domain+++IPR035899///Dbl homology (DH) domain superfamily+++IPR015123///Bcr-Abl oncoprotein oligomerisation+++IPR035892///C2 domain superfamily+++IPR000008///C2 domain+++IPR008936///Rho GTPase activation protein+++IPR000198///Rho GTPase-activating protein domain+++IPR037769///Abr/Bcr+++IPR001849///Pleckstrin homology domain+++IPR036481///Bcr-Abl oncoprotein oligomerisation domain superfamily+++IPR001331///Guanine-nucleotide dissociation stimulator, CDC24, conserved site","[ABR_BOVIN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_HUMAN|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_MOUSE|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[ABR_XENTR|diamond]RecName: Full=Active breakpoint cluster region-related protein;+++[BCR_HUMAN|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1; AltName: Full=Renal carcinoma antigen NY-REN-26;+++[BCR_MOUSE|diamond]RecName: Full=Breakpoint cluster region protein; EC=2.7.11.1;"]
[102724770,"'LOC102724770'",128.29,137.74,133.015,"00330///Arginine and proline metabolism+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0031012///extracellular matrix+++GO:0005634///nucleus","GO:0004657///proline dehydrogenase activity","GO:0007155///cell adhesion+++GO:0009887///animal organ morphogenesis","IPR010849///Gonadal family","[DGCR6_HUMAN|Reviewed]RecName: Full=Protein DGCR6; AltName: Full=DiGeorge syndrome critical region 6;+++[X5D7D2_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region 6 isoform D {ECO:0000313|EMBL:AHW56460.1}; Flags: Fragment;"]
[102724788,"'LOC102724788'",25,21,23,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00330///Arginine and proline metabolism","H00190///Hyperprolinemia (HP)",null,"R10507///L-proline:(acceptor) oxidoreductase   L-Proline + FAD <=> (S)-1-Pyrroline-5-carboxylate + FADH2","GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix","GO:0004657///proline dehydrogenase activity+++GO:0071949///FAD binding","GO:0019470///4-hydroxyproline catabolic process+++GO:0010133///proline catabolic process to glutamate+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0006562///proline catabolic process+++GO:0010942///positive regulation of cell death+++GO:0006560///proline metabolic process","IPR029041///FAD-linked oxidoreductase-like+++IPR015659///Proline oxidase family+++IPR002872///Proline dehydrogenase domain","[PROD_BOVIN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000250|UniProtKB:O43272}; EC=1.5.5.2; AltName: Full=Proline oxidase {ECO:0000250|UniProtKB:O43272}; Flags: Precursor;+++[PROD_CAEEL|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;+++[PROD_DROME|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; AltName: Full=Protein sluggish-A; Flags: Precursor;+++[PROD_HUMAN|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial {ECO:0000305}; EC=1.5.5.2 {ECO:0000269|PubMed:15662599}; AltName: Full=Proline oxidase; AltName: Full=Proline oxidase 2; AltName: Full=p53-induced gene 6 protein; Flags: Precursor;+++[PROD_MOUSE|diamond]RecName: Full=Proline dehydrogenase 1, mitochondrial; EC=1.5.5.2; AltName: Full=Proline oxidase; Flags: Precursor;"]
[102724813,"'LOC102724813'",11.01,14,12.505,null,"H00591///Facioscapulohumeral muscular dystrophy (FSHD)",null,null,"GO:0015030///Cajal body+++GO:0005730///nucleolus+++GO:0030018///Z disc+++GO:0071013///catalytic step 2 spliceosome+++GO:0055120///striated muscle dense body","GO:0051015///actin filament binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006364///rRNA processing+++GO:0007517///muscle organ development","IPR008999///Actin-crosslinking+++IPR010414///Protein FRG1","[FRG1_DROME|diamond]RecName: Full=Protein FRG1 homolog;+++[FRG1_HUMAN|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_MOUSE|diamond]RecName: Full=Protein FRG1; AltName: Full=FSHD region gene 1 protein;+++[FRG1_TAKRU|diamond]RecName: Full=Protein FRG1;+++[FRG1_XENLA|diamond]RecName: Full=Protein FRG1 {ECO:0000250|UniProtKB:Q14331};"]
[102724843,"'LOC102724843'",148.61,192.72,170.665,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane","GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003677///DNA binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0006351///transcription, DNA-templated+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0043066///negative regulation of apoptotic process+++GO:0001933///negative regulation of protein phosphorylation","IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR005135///Endonuclease/exonuclease/phosphatase+++IPR036236///Zinc finger C2H2 superfamily+++IPR036412///HAD-like superfamily+++IPR000477///Reverse transcriptase domain+++IPR023214///HAD superfamily+++IPR004274///FCP1 homology domain+++IPR011948///Dullard phosphatase domain, eukaryotic+++IPR013544///Domain of unknown function DUF1725","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724951,"'LOC102724951'",73.63,70.29,71.96,{"$nulls":4},"GO:0005634///nucleus+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane+++GO:0005737///cytoplasm","GO:0004721///phosphoprotein phosphatase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006470///protein dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0008284///positive regulation of cell proliferation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043066///negative regulation of apoptotic process","IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR036412///HAD-like superfamily+++IPR013544///Domain of unknown function DUF1725+++IPR005135///Endonuclease/exonuclease/phosphatase+++IPR000477///Reverse transcriptase domain+++IPR011948///Dullard phosphatase domain, eukaryotic+++IPR004274///FCP1 homology domain+++IPR023214///HAD superfamily","[Q69YS9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667B1610 {ECO:0000313|EMBL:CAH10643.1};"]
[102724965,"'LOC102724965'",3,0,1.5,{"$nulls":8},"[A0A2Y9SDV6_PHYCD|diamond]SubName: Full=uncharacterized protein LOC102995166 {ECO:0000313|RefSeq:XP_023974475.1};"]
[102724984,"'LOC102724984'",3.94,4.16,4.05,{"$nulls":3},"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0030170///pyridoxal phosphate binding+++GO:0045296///cadherin binding+++GO:0016831///carboxy-lyase activity","GO:0019752///carboxylic acid metabolic process","IPR015424///Pyridoxal phosphate-dependent transferase+++IPR015421///Pyridoxal phosphate-dependent transferase, major domain+++IPR002129///Pyridoxal phosphate-dependent decarboxylase+++IPR018795///Protein of unknown function DUF2152","[K2013_BOVIN|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_HUMAN|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_MOUSE|diamond]RecName: Full=Uncharacterized protein KIAA2013; Flags: Precursor;+++[K2013_XENLA|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[K2013_XENTR|diamond]RecName: Full=Uncharacterized protein KIAA2013 homolog; Flags: Precursor;+++[PDXD1_BOVIN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_HUMAN|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_MOUSE|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD1_XENLA|diamond]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[PDXD2_HUMAN|diamond]RecName: Full=Putative pyridoxal-dependent decarboxylase domain-containing protein 2; EC=4.1.1.-; AltName: Full=pyridoxal-dependent decarboxylase domain-containing 2 pseudogene;"]
[102724985,"'LOC102724985'",682.23,636.93,659.58,null,"H00542///Polycystic kidney disease+++H01728///Potter syndrome",null,"R11559///protein N-terminal asparagine amidohydrolase L-Asparaginyl-protein + H2O <=> L-Aspartyl-protein + Ammonia","GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0016328///lateral plasma membrane+++GO:0005654///nucleoplasm+++GO:0005929///cilium+++GO:0002133///polycystin complex+++GO:0016323///basolateral plasma membrane+++GO:0031514///motile cilium+++GO:0005887///integral component of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0060170///ciliary membrane+++GO:0030660///Golgi-associated vesicle membrane","GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0030246///carbohydrate binding+++GO:0001181///RNA polymerase I general transcription initiation factor activity+++GO:0005262///calcium channel activity+++GO:0001042///RNA polymerase I core binding+++GO:0045296///cadherin binding+++GO:0008418///protein-N-terminal asparagine amidohydrolase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0016831///carboxy-lyase activity+++GO:0044325///ion channel binding+++GO:0001164///RNA polymerase I CORE element sequence-specific DNA binding","GO:0042254///ribosome biogenesis+++GO:0008344///adult locomotory behavior+++GO:0030010///establishment of cell polarity+++GO:0008283///cell proliferation+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0072177///mesonephric duct development+++GO:0007507///heart development+++GO:0021510///spinal cord development+++GO:0030155///regulation of cell adhesion+++GO:0006611///protein export from nucleus+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0021915///neural tube development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0072205///metanephric collecting duct development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043588///skin development+++GO:0048565///digestive tract development+++GO:0072164///mesonephric tubule development+++GO:0060236///regulation of mitotic spindle organization+++GO:0036303///lymph vessel morphogenesis+++GO:0001889///liver development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001502///cartilage condensation+++GO:0010976///positive regulation of neuron projection development+++GO:0051216///cartilage development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009653///anatomical structure morphogenesis+++GO:0034405///response to fluid shear stress+++GO:0007613///memory+++GO:0072237///metanephric proximal tubule development+++GO:0007160///cell-matrix adhesion+++GO:0019752///carboxylic acid metabolic process+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0007050///cell cycle arrest+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0001701///in utero embryonic development+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0070588///calcium ion transmembrane transport+++GO:0007259///JAK-STAT cascade+++GO:0048872///homeostasis of number of cells+++GO:0060674///placenta blood vessel development+++GO:0001822///kidney development+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0007028///cytoplasm organization+++GO:0072218///metanephric ascending thin limb development+++GO:0001892///embryonic placenta development+++GO:0007000///nucleolus organization+++GO:0048806///genitalia development+++GO:0050982///detection of mechanical stimulus+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0060428///lung epithelium development+++GO:2000142///regulation of DNA-templated transcription, initiation+++GO:0032092///positive regulation of protein binding+++GO:0007204///positive regulation of cytosolic calcium ion concentration","IPR002129///Pyridoxal phosphate-dependent decarboxylase+++IPR015424///Pyridoxal phosphate-dependent transferase+++IPR015421///Pyridoxal phosphate-dependent transferase, major domain","[PDXD1_HUMAN|Reviewed]RecName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1; EC=4.1.1.-;+++[H3BND4_HUMAN|Unreviewed]SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000454791};+++[Q86XE2_HUMAN|Unreviewed]SubName: Full=PDXDC1 protein {ECO:0000313|EMBL:AAH45554.2}; SubName: Full=Pyridoxal-dependent decarboxylase domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000437835};"]
[102724993,"'LOC102724993'",888.49,861.81,875.15,null,"H01728///Potter syndrome+++H00542///Polycystic kidney disease",null,null,"GO:0002133///polycystin complex+++GO:0060170///ciliary membrane+++GO:0016021///integral component of membrane+++GO:0016328///lateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005929///cilium+++GO:0016323///basolateral plasma membrane+++GO:0009986///cell surface+++GO:0000139///Golgi membrane+++GO:0031514///motile cilium+++GO:0030660///Golgi-associated vesicle membrane+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm","GO:0019901///protein kinase binding+++GO:0030246///carbohydrate binding+++GO:0005262///calcium channel activity+++GO:0019904///protein domain specific binding+++GO:0044325///ion channel binding","GO:0036303///lymph vessel morphogenesis+++GO:0048565///digestive tract development+++GO:0043588///skin development+++GO:0001502///cartilage condensation+++GO:0032092///positive regulation of protein binding+++GO:0061136///regulation of proteasomal protein catabolic process+++GO:0072177///mesonephric duct development+++GO:0060674///placenta blood vessel development+++GO:0051216///cartilage development+++GO:0072218///metanephric ascending thin limb development+++GO:0060428///lung epithelium development+++GO:0072237///metanephric proximal tubule development+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0007259///JAK-STAT cascade+++GO:0070588///calcium ion transmembrane transport+++GO:0001701///in utero embryonic development+++GO:0072164///mesonephric tubule development+++GO:0030010///establishment of cell polarity+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0021915///neural tube development+++GO:0001892///embryonic placenta development+++GO:0048806///genitalia development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0015031///protein transport+++GO:0072287///metanephric distal tubule morphogenesis+++GO:0021510///spinal cord development+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0072205///metanephric collecting duct development+++GO:0060236///regulation of mitotic spindle organization+++GO:0034405///response to fluid shear stress+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0001822///kidney development+++GO:0007160///cell-matrix adhesion+++GO:0007507///heart development+++GO:0030155///regulation of cell adhesion+++GO:0050982///detection of mechanical stimulus+++GO:0006611///protein export from nucleus+++GO:0051028///mRNA transport+++GO:0001889///liver development+++GO:0018105///peptidyl-serine phosphorylation+++GO:0009653///anatomical structure morphogenesis+++GO:0007050///cell cycle arrest","IPR001304///C-type lectin-like+++IPR035986///PKD domain superfamily+++IPR000203///GPS motif+++IPR013784///Carbohydrate-binding-like fold+++IPR000434///Polycystic kidney disease type 1 protein+++IPR014010///REJ domain+++IPR013122///Polycystin cation channel, PKD1/PKD2+++IPR003591///Leucine-rich repeat, typical subtype+++IPR000372///Leucine-rich repeat N-terminal domain+++IPR000601///PKD domain+++IPR002889///Carbohydrate-binding WSC+++IPR006228///Polycystin cation channel+++IPR016186///C-type lectin-like/link domain superfamily+++IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR016187///C-type lectin fold+++IPR036392///PLAT/LH2 domain superfamily+++IPR002859///PKD/REJ-like domain+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR022409///PKD/Chitinase domain+++IPR009443///Nuclear pore complex interacting protein+++IPR001024///PLAT/LH2 domain+++IPR008969///Carboxypeptidase-like, regulatory domain superfamily","[NOMO1_HUMAN|diamond]RecName: Full=Nodal modulator 1; AltName: Full=pM5 protein; Flags: Precursor;+++[NOMO1_MOUSE|diamond]RecName: Full=Nodal modulator 1 {ECO:0000312|EMBL:AAH72630.1}; Flags: Precursor;+++[NOMO2_HUMAN|diamond]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[NOMO3_HUMAN|diamond]RecName: Full=Nodal modulator 3; AltName: Full=pM5 protein 3; Flags: Precursor;+++[NPIA1_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A1; AltName: Full=Nuclear pore complex-interacting protein; Short=NPIP;+++[NPIA2_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A2;+++[NPIA3_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A3;+++[NPIA5_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A5;+++[NPIA7_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A7;+++[NPIA8_HUMAN|diamond]RecName: Full=Nuclear pore complex-interacting protein family member A8;+++[PKD1_HUMAN|diamond]RecName: Full=Polycystin-1; Short=PC1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein; Flags: Precursor;+++[PKD1_MOUSE|diamond]RecName: Full=Polycystin-1; AltName: Full=Autosomal dominant polycystic kidney disease 1 protein homolog; Flags: Precursor;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[102725009,"'LOC102725009'",22,43,32.5,{"$nulls":4},"GO:0005764///lysosome","GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0007399///nervous system development+++GO:0001501///skeletal system development","IPR013783///Immunoglobulin-like fold+++IPR036156///Beta-Galactosidase/glucuronidase domain superfamily","[BGLR_CHLAE|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor; Fragment;+++[BGLR_FELCA|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[BGLR_HUMAN|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; AltName: Full=Beta-G1; Flags: Precursor;+++[BGLR_PONAB|diamond]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; Flags: Precursor;+++[GUSP1_HUMAN|diamond]RecName: Full=Putative inactive beta-glucuronidase-like protein SMA3;"]
[10273,"'STUB1'",2796,1946,2371,"04141///Protein processing in endoplasmic reticulum+++04120///Ubiquitin mediated proteolysis","H01891///Autosomal recessive spinocerebellar ataxias",null,null,"GO:0000151///ubiquitin ligase complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0030018///Z disc+++GO:0101031///chaperone complex+++GO:0005829///cytosol+++GO:0042405///nuclear inclusion body+++GO:0031371///ubiquitin conjugating enzyme complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0031072///heat shock protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0048156///tau protein binding+++GO:0030674///protein binding, bridging+++GO:0004842///ubiquitin-protein transferase activity+++GO:0051087///chaperone binding+++GO:0042803///protein homodimerization activity+++GO:0051879///Hsp90 protein binding+++GO:0019899///enzyme binding+++GO:0046332///SMAD binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0051787///misfolded protein binding+++GO:0030911///TPR domain binding+++GO:0001664///G protein-coupled receptor binding+++GO:0030544///Hsp70 protein binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0019900///kinase binding","GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051865///protein autoubiquitination+++GO:0090035///positive regulation of chaperone-mediated protein complex assembly+++GO:0061684///chaperone-mediated autophagy+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination+++GO:0030579///ubiquitin-dependent SMAD protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0071218///cellular response to misfolded protein+++GO:0051604///protein maturation+++GO:0032091///negative regulation of protein binding+++GO:0071456///cellular response to hypoxia+++GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0034605///cellular response to heat+++GO:0031398///positive regulation of protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031943///regulation of glucocorticoid metabolic process+++GO:0002931///response to ischemia+++GO:0006281///DNA repair+++GO:0038128///ERBB2 signaling pathway+++GO:0031647///regulation of protein stability+++GO:0030968///endoplasmic reticulum unfolded protein response","IPR019734///Tetratricopeptide repeat+++IPR003613///U box domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR011990///Tetratricopeptide-like helical domain superfamily","[CHIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:11557750, ECO:0000269|PubMed:15466472}; AltName: Full=Antigen NY-CO-7 {ECO:0000303|PubMed:9610721}; AltName: Full=CLL-associated antigen KW-8 {ECO:0000303|PubMed:12200376}; AltName: Full=Carboxy terminus of Hsp70-interacting protein {ECO:0000303|PubMed:10330192}; AltName: Full=RING-type E3 ubiquitin transferase CHIP {ECO:0000305}; AltName: Full=STIP1 homology and U box-containing protein 1 {ECO:0000312|HGNC:HGNC:11427};+++[H3BS86_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000456591}; Flags: Fragment;+++[H3BTA3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457090}; Flags: Fragment;+++[H3BUD0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000457583}; Flags: Fragment;+++[V9GYH3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CHIP {ECO:0000313|Ensembl:ENSP00000476751}; Flags: Fragment;"]
[10274,"'STAG1'",181,253,217,"04113///Meiosis - yeast+++04110///Cell cycle+++04111///Cell cycle - yeast","H00773///Autosomal dominant mental retardation",null,null,"GO:0016363///nuclear matrix+++GO:0097431///mitotic spindle pole+++GO:0005694///chromosome+++GO:0005829///cytosol+++GO:0008278///cohesin complex+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000775///chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006351///transcription, DNA-templated+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1901673///regulation of mitotic spindle assembly+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0032197///transposition, RNA-mediated+++GO:0051301///cell division","IPR016024///Armadillo-type fold+++IPR039662///Cohesin subunit Scc3/SA+++IPR013721///STAG+++IPR020839///Stromalin conservative domain","[STAG1_HUMAN|Reviewed]RecName: Full=Cohesin subunit SA-1; AltName: Full=SCC3 homolog 1; AltName: Full=Stromal antigen 1;+++[Q4LE48_HUMAN|Unreviewed]SubName: Full=STAG1 variant protein {ECO:0000313|EMBL:BAE06105.1}; Flags: Fragment;"]
[10276,"'NET1'",131,114,122.5,"04540///Gap junction+++04210///Apoptosis+++04530///Tight junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H00268///Lissencephaly (LIS)+++H00058///Amyotrophic lateral sclerosis (ALS)+++H00271///Polymicrogyria",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0005200///structural constituent of cytoskeleton+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0017049///GTP-Rho binding+++GO:0003924///GTPase activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005525///GTP binding","GO:0035023///regulation of Rho protein signal transduction+++GO:0051451///myoblast migration+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071479///cellular response to ionizing radiation+++GO:0007165///signal transduction+++GO:0070301///cellular response to hydrogen peroxide+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0007017///microtubule-based process+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0001558///regulation of cell growth","IPR011993///PH-like domain superfamily+++IPR035899///Dbl homology (DH) domain superfamily+++IPR001849///Pleckstrin homology domain+++IPR001331///Guanine-nucleotide dissociation stimulator, CDC24, conserved site+++IPR037853///Net1, PH domain+++IPR000219///Dbl homology (DH) domain","[ARHG8_HUMAN|Reviewed]RecName: Full=Neuroepithelial cell-transforming gene 1 protein; AltName: Full=Proto-oncogene p65 Net1; AltName: Full=Rho guanine nucleotide exchange factor 8;+++[Q5SQI5_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW86446.1}; SubName: Full=cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 protein {ECO:0000313|EMBL:BAG61338.1};+++[Q5SQI7_HUMAN|Unreviewed]SubName: Full=Neuroepithelial cell transforming gene 1, isoform CRA_a {ECO:0000313|EMBL:EAW86445.1}; SubName: Full=cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNA {ECO:0000313|EMBL:BAG37941.1};"]
[10277,"'UBE4B'",938,1177,1057.5,"04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0051117///ATPase binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0044257///cellular protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0051865///protein autoubiquitination+++GO:0034976///response to endoplasmic reticulum stress+++GO:0009411///response to UV+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0008626///granzyme-mediated apoptotic signaling pathway+++GO:0016567///protein ubiquitination+++GO:0006513///protein monoubiquitination+++GO:0031175///neuron projection development+++GO:0000209///protein polyubiquitination","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR019474///Ubiquitin conjugation factor E4, core+++IPR003613///U box domain","[UBE4B_HUMAN|Reviewed]RecName: Full=Ubiquitin conjugation factor E4 B {ECO:0000305}; EC=2.3.2.27 {ECO:0000250|UniProtKB:Q9ES00}; AltName: Full=Homozygously deleted in neuroblastoma 1 {ECO:0000312|EMBL:BAB40446.1}; AltName: Full=RING-type E3 ubiquitin transferase E4 B; AltName: Full=Ubiquitin fusion degradation protein 2 {ECO:0000312|EMBL:AAD02233.1};+++[B1AQ61_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000366358};+++[K7EP75_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000467258}; Flags: Fragment;+++[K7ERA7_HUMAN|Unreviewed]SubName: Full=Ubiquitin conjugation factor E4 B {ECO:0000313|Ensembl:ENSP00000468178}; Flags: Fragment;"]
[10278,"'EFS'",4,5,4.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0017124///SH3 domain binding","GO:0016477///cell migration+++GO:0035556///intracellular signal transduction+++GO:0090527///actin filament reorganization+++GO:0007155///cell adhesion","IPR036028///SH3-like domain superfamily+++IPR035747///Embryonal Fyn-associated substrate, SH3 domain+++IPR037362///CAS family+++IPR021901///CAS family, C-terminal+++IPR001452///SH3 domain","[EFS_HUMAN|Reviewed]RecName: Full=Embryonal Fyn-associated substrate; Short=hEFS; AltName: Full=Cas scaffolding protein family member 3;"]
[10279,"'PRSS16'",14,9,11.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0005764///lysosome+++GO:0016020///membrane","GO:0008239///dipeptidyl-peptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis+++GO:0030163///protein catabolic process","IPR029058///Alpha/Beta hydrolase fold+++IPR008758///Peptidase S28","[TSSP_HUMAN|Reviewed]RecName: Full=Thymus-specific serine protease; EC=3.4.-.-; AltName: Full=Serine protease 16; Flags: Precursor;+++[B4DZV2_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000396589}; SubName: Full=cDNA FLJ52815, highly similar to Thymus-specific serine protease {ECO:0000313|EMBL:BAG64214.1};+++[C9JDN6_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419492};+++[F2Z2N5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000404349};+++[F8WBG5_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418036};+++[F8WF25_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419437};+++[H0Y893_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000418710}; Flags: Fragment;+++[H0Y8B9_HUMAN|Unreviewed]SubName: Full=Thymus-specific serine protease {ECO:0000313|Ensembl:ENSP00000419538}; Flags: Fragment;"]
[1028,"'CDKN1C'",98,63,80.5,"04110///Cell cycle","H01772///Adrenal hypoplasia congenita+++H00713///Beckwith-Wiedemann syndrome+++H00033///Adrenal carcinoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004860///protein kinase inhibitor activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity","GO:0071514///genetic imprinting+++GO:0001501///skeletal system development+++GO:0035264///multicellular organism growth+++GO:0001822///kidney development+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:1902746///regulation of lens fiber cell differentiation+++GO:0007049///cell cycle+++GO:0060065///uterus development+++GO:0007096///regulation of exit from mitosis+++GO:0033673///negative regulation of kinase activity+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0007050///cell cycle arrest+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042326///negative regulation of phosphorylation+++GO:0030099///myeloid cell differentiation+++GO:0055123///digestive system development+++GO:0043010///camera-type eye development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007568///aging+++GO:1904030///negative regulation of cyclin-dependent protein kinase activity+++GO:0016310///phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001890///placenta development+++GO:0030325///adrenal gland development+++GO:0060669///embryonic placenta morphogenesis+++GO:0042551///neuron maturation+++GO:0007346///regulation of mitotic cell cycle","IPR029842///Cyclin-dependent kinase inhibitor 1C+++IPR003175///Cyclin-dependent kinase inhibitor","[CDN1C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 1C; AltName: Full=Cyclin-dependent kinase inhibitor p57; AltName: Full=p57Kip2;+++[A0A0G2JH30_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000321019};+++[A0A0G2JPX0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000484462};+++[A0A2R8YFP9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000496631};+++[A6NK88_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C {ECO:0000313|Ensembl:ENSP00000370101};+++[B2D1N3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 1C transcript variant 3 {ECO:0000313|EMBL:ACB69757.1};"]
[10280,"'SIGMAR1'",4592,3837,4214.5,null,"H00856///Distal hereditary motor neuropathies (dHMN)+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0016021///integral component of membrane+++GO:0005640///nuclear outer membrane+++GO:0030426///growth cone+++GO:0014069///postsynaptic density+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005635///nuclear envelope+++GO:0005637///nuclear inner membrane+++GO:0042995///cell projection+++GO:0045211///postsynaptic membrane+++GO:0005811///lipid droplet+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0004985///opioid receptor activity+++GO:0008144///drug binding","GO:0006869///lipid transport+++GO:0036474///cell death in response to hydrogen peroxide+++GO:0038003///opioid receptor signaling pathway+++GO:0070207///protein homotrimerization+++GO:0007399///nervous system development+++GO:0043523///regulation of neuron apoptotic process","IPR006716///ERG2/sigma1 receptor-like","[SGMR1_HUMAN|Reviewed]RecName: Full=Sigma non-opioid intracellular receptor 1; AltName: Full=Aging-associated gene 8 protein; AltName: Full=SR31747-binding protein; Short=SR-BP; AltName: Full=Sigma 1-type opioid receptor; Short=SIG-1R; Short=Sigma1-receptor; Short=Sigma1R; Short=hSigmaR1;+++[A2A3U5_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_d {ECO:0000313|EMBL:EAW58436.1}; SubName: Full=cDNA FLJ76396, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF83781.1};+++[B4DR71_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57078, highly similar to Homo sapiens opioid receptor, sigma 1 (OPRS1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61183.1};+++[Q5T1J1_HUMAN|Unreviewed]SubName: Full=HCG20471, isoform CRA_c {ECO:0000313|EMBL:EAW58433.1}; SubName: Full=Sigma non-opioid intracellular receptor 1 {ECO:0000313|Ensembl:ENSP00000368170};"]
[102800317,"'TPTEP2-CSNK1E'",81.79,49.26,65.525,"04068///FoxO signaling pathway+++04711///Circadian rhythm - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species+++04710///Circadian rhythm+++04310///Wnt signaling pathway+++04391///Hippo signaling pathway - fly+++04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042752///regulation of circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0008360///regulation of cell shape+++GO:2000052///positive regulation of non-canonical Wnt signaling pathway+++GO:0006281///DNA repair+++GO:0007165///signal transduction+++GO:0032197///transposition, RNA-mediated+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0006468///protein phosphorylation+++GO:1903827///regulation of cellular protein localization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1905426///positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation+++GO:0006897///endocytosis+++GO:0060070///canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0032091///negative regulation of protein binding+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006310///DNA recombination+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000086///G2/M transition of mitotic cell cycle","IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site+++IPR000719///Protein kinase domain","[KC1E_HUMAN|Reviewed]RecName: Full=Casein kinase I isoform epsilon; Short=CKI-epsilon; Short=CKIe; EC=2.7.11.1;+++[B3KRV2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34950 fis, clone NT2RP7017284, highly similar to Casein kinase I isoform epsilon {ECO:0000313|EMBL:BAG52514.1};+++[Q5U045_HUMAN|Unreviewed]SubName: Full=Casein kinase 1 epsilon {ECO:0000313|EMBL:ABM64212.1}; SubName: Full=Casein kinase 1, epsilon {ECO:0000313|EMBL:AAV38634.1}; SubName: Full=HCG2014051, isoform CRA_a {ECO:0000313|EMBL:EAW60228.1};"]
[10282,"'BET1'",133,114,123.5,"04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0030173///integral component of Golgi membrane","GO:0005515///protein binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating","IPR039899///BET1, SNARE domain+++IPR039897///BET1-like protein+++IPR000727///Target SNARE coiled-coil homology domain","[BET1_HUMAN|Reviewed]RecName: Full=BET1 homolog; Short=hBET1; AltName: Full=Golgi vesicular membrane-trafficking protein p18;+++[C9JTT8_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000413063};+++[H7C1N3_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000401260}; Flags: Fragment;+++[Q53XK0_HUMAN|Unreviewed]SubName: Full=BET1 homolog (S. cerevisiae) {ECO:0000313|EMBL:AAP88855.1}; SubName: Full=BET1 homolog (S. cerevisiae), isoform CRA_d {ECO:0000313|EMBL:EAW76803.1}; SubName: Full=cDNA, FLJ94635, Homo sapiens BET1 homolog (S. cerevisiae) (BET1), mRNA {ECO:0000313|EMBL:BAG36696.1};+++[Q68DU7_HUMAN|Unreviewed]SubName: Full=BET1 homolog {ECO:0000313|Ensembl:ENSP00000350125};"]
[10283,"'CWC27'",252,214,233,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0071012///catalytic step 1 spliceosome","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016018///cyclosporin A binding","GO:0000413///protein peptidyl-prolyl isomerization+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006457///protein folding","IPR029000///Cyclophilin-like domain superfamily+++IPR024936///Cyclophilin-type peptidyl-prolyl cis-trans isomerase+++IPR002130///Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain+++IPR020892///Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site","[CWC27_HUMAN|Reviewed]RecName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000305}; AltName: Full=Antigen NY-CO-10 {ECO:0000303|PubMed:9610721}; AltName: Full=Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog {ECO:0000305|PubMed:20676357}; Short=PPIase CWC27 {ECO:0000305|PubMed:20676357}; AltName: Full=Serologically defined colon cancer antigen 10;+++[D6REK3_HUMAN|Unreviewed]SubName: Full=Spliceosome-associated protein CWC27 homolog {ECO:0000313|Ensembl:ENSP00000426802};"]
[10284,"'SAP18'",1194,829,1011.5,"03015///mRNA surveillance pathway+++03013///RNA transport",null,"M00430///Exon junction complex (EJC)",null,"GO:0005634///nucleus+++GO:0035145///exon-exon junction complex+++GO:0000118///histone deacetylase complex+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0061574///ASAP complex","GO:0004407///histone deacetylase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity","GO:0008380///RNA splicing+++GO:0043065///positive regulation of apoptotic process+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006397///mRNA processing+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0048025///negative regulation of mRNA splicing, via spliceosome","IPR010516///Sin3 associated polypeptide p18+++IPR017250///Histone deacetylase complex, SAP18 subunit","[SAP18_HUMAN|Reviewed]RecName: Full=Histone deacetylase complex subunit SAP18; AltName: Full=18 kDa Sin3-associated polypeptide; AltName: Full=2HOR0202; AltName: Full=Cell growth-inhibiting gene 38 protein; AltName: Full=Sin3-associated polypeptide p18;+++[H7BZW6_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000391846}; Flags: Fragment;+++[U3KPY7_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475358}; Flags: Fragment;+++[U3KQ12_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000475435}; Flags: Fragment;+++[X6RAL5_HUMAN|Unreviewed]SubName: Full=Histone deacetylase complex subunit SAP18 {ECO:0000313|Ensembl:ENSP00000371973};"]
[10285,"'SMNDC1'",178,163,170.5,"03040///Spliceosome",{"$nulls":3},"GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0008380///RNA splicing+++GO:0006915///apoptotic process","IPR002999///Tudor domain+++IPR010304///Survival motor neuron","[SPF30_HUMAN|Reviewed]RecName: Full=Survival of motor neuron-related-splicing factor 30; AltName: Full=30 kDa splicing factor SMNrp; AltName: Full=SMN-related protein; AltName: Full=Survival motor neuron domain-containing protein 1;"]
[10286,"'BCAS2'",360,315,337.5,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0005634///nucleus+++GO:0000974///Prp19 complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005813///centrosome+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005730///nucleolus","GO:0005515///protein binding","GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000375///RNA splicing, via transesterification reactions","IPR008409///Pre-mRNA-splicing factor SPF27","[SPF27_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SPF27; AltName: Full=Breast carcinoma-amplified sequence 2; AltName: Full=DNA amplified in mammary carcinoma 1 protein; AltName: Full=Spliceosome-associated protein SPF 27;+++[B2R7W3_HUMAN|Unreviewed]SubName: Full=Breast carcinoma amplified sequence 2 {ECO:0000313|EMBL:BAG70059.1}; SubName: Full=Breast carcinoma amplified sequence 2, isoform CRA_a {ECO:0000313|EMBL:EAW56602.1}; SubName: Full=cDNA, FLJ93631, Homo sapiens breast carcinoma amplified sequence 2 (BCAS2), mRNA {ECO:0000313|EMBL:BAG35960.1};"]
[10287,"'RGS19'",330,251,290.5,{"$nulls":4},"GO:0005903///brush border+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030136///clathrin-coated vesicle","GO:0001965///G-protein alpha-subunit binding+++GO:0005515///protein binding","GO:0007264///small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009968///negative regulation of signal transduction+++GO:0045471///response to ethanol+++GO:0006914///autophagy","IPR036305///RGS domain superfamily+++IPR016137///RGS domain","[RGS19_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 19; Short=RGS19; AltName: Full=G-alpha-interacting protein; Short=GAIP;+++[B4DP94_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59828, highly similar to Regulator of G-protein signaling 19 {ECO:0000313|EMBL:BAG60506.1};+++[Q6I9S5_HUMAN|Unreviewed]SubName: Full=RGS19 protein {ECO:0000313|EMBL:CAG33711.1};+++[Q9H2T9_HUMAN|Unreviewed]SubName: Full=G alpha interacting protein {ECO:0000313|EMBL:AAG42352.1}; Flags: Fragment;"]
[10289,"'EIF1B'",387,338,362.5,"03013///RNA transport",{"$nulls":3},"GO:0005575///cellular_component+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0003723///RNA binding+++GO:0043024///ribosomal small subunit binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006446///regulation of translational initiation+++GO:0006412///translation+++GO:0006413///translational initiation","IPR001950///SUI1 domain+++IPR036877///SUI1 domain superfamily+++IPR005874///Eukaryotic translation initiation factor SUI1","[EIF1B_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 1b; Short=eIF1b; AltName: Full=Protein translation factor SUI1 homolog GC20;+++[Q6FG85_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 1B, isoform CRA_a {ECO:0000313|EMBL:EAW64598.1}; SubName: Full=GC20 protein {ECO:0000313|EMBL:CAG47019.1}; SubName: Full=cDNA, FLJ92189, Homo sapiens translation factor sui1 homolog (GC20), mRNA {ECO:0000313|EMBL:BAG34863.1}; Flags: Fragment;"]
[1029,"'CDKN2A'",23459,17048,20253.5,"04934///Cushing's syndrome+++05220///Chronic myeloid leukemia+++05225///Hepatocellular carcinoma+++05203///Viral carcinogenesis+++01524///Platinum drug resistance+++05214///Glioma+++05223///Non-small cell lung cancer+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05163///Human cytomegalovirus infection+++05212///Pancreatic cancer+++04218///Cellular senescence+++05219///Bladder cancer+++04110///Cell cycle+++05166///HTLV-I infection+++01522///Endocrine resistance+++05218///Melanoma+++05200///Pathways in cancer","H01513///Retinoblastoma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00054///Nasopharyngeal cancer+++H01556///Meningioma+++H00015///Malignant pleural mesothelioma+++H00042///Glioma+++H00008///Burkitt lymphoma+++H00040///Squamous cell carcinoma+++H00009///Adult T-cell leukemia+++H00017///Esophageal cancer+++H00014///Non-small cell lung cancer+++H00025///Penile cancer+++H00004///Chronic myeloid leukemia (CML)+++H00016///Oral cancer+++H01509///Tonsillar cancer+++H01464///Mantle cell lymphoma+++H00055///Laryngeal cancer+++H00047///Gallbladder cancer+++H00048///Hepatocellular carcinoma+++H01508///Salivary gland cancer+++H00046///Cholangiocarcinoma+++H00409///Type II diabetes mellitus+++H00038///Melanoma+++H00022///Bladder cancer+++H00019///Pancreatic cancer",null,null,"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0035985///senescence-associated heterochromatin focus+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0003723///RNA binding+++GO:0055105///ubiquitin-protein transferase inhibitor activity+++GO:0097718///disordered domain specific binding+++GO:0019901///protein kinase binding+++GO:0051059///NF-kappaB binding+++GO:1990948///ubiquitin ligase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0003677///DNA binding+++GO:0002039///p53 binding+++GO:0019789///SUMO transferase activity+++GO:0016301///kinase activity","GO:0050821///protein stabilization+++GO:0090399///replicative senescence+++GO:1900182///positive regulation of protein localization to nucleus+++GO:0033235///positive regulation of protein sumoylation+++GO:0042326///negative regulation of phosphorylation+++GO:0000422///autophagy of mitochondrion+++GO:0046825///regulation of protein export from nucleus+++GO:0030889///negative regulation of B cell proliferation+++GO:0000209///protein polyubiquitination+++GO:2000435///negative regulation of protein neddylation+++GO:0035986///senescence-associated heterochromatin focus assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0016925///protein sumoylation+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007265///Ras protein signal transduction+++GO:0007050///cell cycle arrest+++GO:0051882///mitochondrial depolarization+++GO:0071158///positive regulation of cell cycle arrest+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0031648///protein destabilization+++GO:0016310///phosphorylation+++GO:0008637///apoptotic mitochondrial changes+++GO:0048103///somatic stem cell division+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0090398///cellular senescence+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0030308///negative regulation of cell growth+++GO:1902510///regulation of apoptotic DNA fragmentation+++GO:0006469///negative regulation of protein kinase activity+++GO:0070534///protein K63-linked ubiquitination+++GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:1903051///negative regulation of proteolysis involved in cellular protein catabolic process+++GO:2000774///positive regulation of cellular senescence+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006915///apoptotic process+++GO:1990000///amyloid fibril formation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:0031647///regulation of protein stability+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0034393///positive regulation of smooth muscle cell apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:2000111///positive regulation of macrophage apoptotic process+++GO:0006364///rRNA processing+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0051444///negative regulation of ubiquitin-protein transferase activity+++GO:0032088///negative regulation of NF-kappaB transcription factor activity","IPR010868///Tumor suppressor ARF+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily","[ARF_HUMAN|Reviewed]RecName: Full=Tumor suppressor ARF {ECO:0000305}; AltName: Full=Alternative reading frame {ECO:0000303|PubMed:9724636}; Short=ARF {ECO:0000303|PubMed:9724636}; AltName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=p14ARF {ECO:0000303|PubMed:9724636};+++[CDN2A_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}; AltName: Full=Cyclin-dependent kinase 4 inhibitor A; Short=CDK4I; AltName: Full=Multiple tumor suppressor 1; Short=MTS-1; AltName: Full=p16-INK4a; Short=p16-INK4; Short=p16INK4A;+++[A7LNE7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:ABS32187.1}; Flags: Fragment;+++[D1LYX3_HUMAN|Unreviewed]SubName: Full=Truncated tumor suppressor protein P16 {ECO:0000313|EMBL:ACY78326.1};+++[J3QRG6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000464202};+++[K7ENC6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000466887};+++[K7ES20_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|Ensembl:ENSP00000468510};+++[K7PML8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AFN61600.1};+++[L8E941_HUMAN|Unreviewed]SubName: Full=Alternative protein CDKN2A {ECO:0000313|EMBL:CCQ43815.1};+++[Q208B5_HUMAN|Unreviewed]SubName: Full=p16 {ECO:0000313|EMBL:ABD72255.1}; Flags: Fragment;+++[Q2MJK0_HUMAN|Unreviewed]SubName: Full=p16 protein {ECO:0000313|EMBL:ABC50001.1}; Flags: Fragment;+++[Q5ZEY9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:CAH59950.1}; Flags: Fragment;+++[Q9UPB7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2A {ECO:0000313|EMBL:AAD02319.1}; Flags: Fragment;"]
[10290,"'SPEG'",2751,3525,3138,null,"H00700///Centronuclear myopathy",null,null,"GO:0005634///nucleus","GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding","GO:0072358///cardiovascular system development+++GO:0030154///cell differentiation+++GO:0016310///phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0006468///protein phosphorylation+++GO:0042692///muscle cell differentiation+++GO:0007517///muscle organ development","IPR007110///Immunoglobulin-like domain+++IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold+++IPR013098///Immunoglobulin I-set+++IPR003961///Fibronectin type III+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR011009///Protein kinase-like domain superfamily+++IPR036116///Fibronectin type III superfamily+++IPR003598///Immunoglobulin subtype 2+++IPR015726///Serine/threonine protein kinase, striated muscle-specific+++IPR008271///Serine/threonine-protein kinase, active site","[SPEG_HUMAN|Reviewed]RecName: Full=Striated muscle preferentially expressed protein kinase; EC=2.7.11.1; AltName: Full=Aortic preferentially expressed protein 1; Short=APEG-1;+++[B9ZVR7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000379926};+++[C9J8D8_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000410986}; Flags: Fragment;+++[C9JWU5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000393134}; Flags: Fragment;+++[F8WCA7_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000406530};+++[G5E9J7_HUMAN|Unreviewed]SubName: Full=Aortic preferentially expressed gene 1, isoform CRA_i {ECO:0000313|EMBL:EAW70750.1}; SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000397514};+++[H0Y3W0_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000387344}; Flags: Fragment;+++[H7BZM6_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000390353}; Flags: Fragment;+++[H7C3Y5_HUMAN|Unreviewed]SubName: Full=Striated muscle preferentially-expressed protein kinase {ECO:0000313|Ensembl:ENSP00000414549}; Flags: Fragment;"]
[10291,"'SF3A1'",3093,3341,3217,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0005684///U2-type spliceosomal complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005686///U2 snRNP+++GO:0071004///U2-type prespliceosome+++GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0000389///mRNA 3'-splice site recognition","IPR022030///Splicing factor 3A subunit 1+++IPR035563///Splicing factor 3A subunit 1, ubiquitin domain+++IPR000061///SWAP/Surp+++IPR000626///Ubiquitin domain+++IPR029071///Ubiquitin-like domain superfamily+++IPR035967///SWAP/Surp superfamily","[SF3A1_HUMAN|Reviewed]RecName: Full=Splicing factor 3A subunit 1; AltName: Full=SF3a120; AltName: Full=Spliceosome-associated protein 114; Short=SAP 114;+++[A0A024R1K8_HUMAN|Unreviewed]SubName: Full=Splicing factor 3a, subunit 1, 120kDa, isoform CRA_a {ECO:0000313|EMBL:EAW59879.1};+++[F8WB66_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000397267};+++[F8WC79_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000412715};+++[H7C1L2_HUMAN|Unreviewed]SubName: Full=Splicing factor 3A subunit 1 {ECO:0000313|Ensembl:ENSP00000400862}; Flags: Fragment;"]
[10293,"'TRAIP'",13,12,12.5,null,"H00992///Seckel syndrome",null,null,"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0016567///protein ubiquitination+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0008283///cell proliferation+++GO:0032688///negative regulation of interferon-beta production+++GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway","IPR001841///Zinc finger, RING-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type","[TRAIP_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRAIP; EC=2.3.2.27; AltName: Full=RING finger protein 206; AltName: Full=RING-type E3 ubiquitin transferase TRAIP {ECO:0000305}; AltName: Full=TRAF-interacting protein;+++[E7EN91_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000418544}; Flags: Fragment;+++[E7ETV1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000420085};+++[E7EVC4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419556};+++[E7EW89_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRAIP {ECO:0000313|Ensembl:ENSP00000419350}; Flags: Fragment;"]
[10294,"'DNAJA2'",609,548,578.5,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0051082///unfolded protein binding+++GO:0051087///chaperone binding+++GO:0001671///ATPase activator activity+++GO:0031072///heat shock protein binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006457///protein folding+++GO:0042026///protein refolding+++GO:0008284///positive regulation of cell proliferation+++GO:0009408///response to heat+++GO:0032781///positive regulation of ATPase activity","IPR001623///DnaJ domain+++IPR036869///Chaperone J-domain superfamily+++IPR008971///HSP40/DnaJ peptide-binding+++IPR001305///Heat shock protein DnaJ, cysteine-rich domain+++IPR018253///DnaJ domain, conserved site+++IPR012724///Chaperone DnaJ+++IPR036410///Heat shock protein DnaJ, cysteine-rich domain superfamily+++IPR002939///Chaperone DnaJ, C-terminal","[DNJA2_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily A member 2; AltName: Full=Cell cycle progression restoration gene 3 protein; AltName: Full=Dnj3; Short=Dj3; AltName: Full=HIRA-interacting protein 4; AltName: Full=Renal carcinoma antigen NY-REN-14; Flags: Precursor;+++[A0A024R6S1_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily A, member 2, isoform CRA_a {ECO:0000313|EMBL:EAW82694.1};+++[A0A087WT48_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000477579}; Flags: Fragment;+++[I3L320_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000460104};"]
[10295,"'BCKDK'",1988,1779,1883.5,null,"H02136///Branched-chain ketoacid dehydrogenase kinase deficiency",null,null,"GO:0005947///mitochondrial alpha-ketoglutarate dehydrogenase complex+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0047323///[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0009083///branched-chain amino acid catabolic process+++GO:0009063///cellular amino acid catabolic process","IPR004358///Signal transduction histidine kinase-related protein, C-terminal+++IPR036890///Histidine kinase/HSP90-like ATPase superfamily+++IPR003594///Histidine kinase/HSP90-like ATPase+++IPR018955///Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal+++IPR005467///Histidine kinase domain+++IPR039028///PDK/BCKDK protein kinase+++IPR036784///Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily","[BCKD_HUMAN|Reviewed]RecName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; EC=2.7.11.4; AltName: Full=Branched-chain alpha-ketoacid dehydrogenase kinase; Short=BCKD-kinase; Short=BCKDHKIN; Flags: Precursor;+++[A0A024QZA9_HUMAN|Unreviewed]SubName: Full=Branched chain ketoacid dehydrogenase kinase, isoform CRA_b {ECO:0000313|EMBL:EAW52162.1};+++[H3BNP3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000454947}; Flags: Fragment;+++[H3BQP2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000455866}; Flags: Fragment;+++[H3BS02_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000456479};+++[H3BTL2_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457226}; Flags: Fragment;+++[H3BUV3_HUMAN|Unreviewed]SubName: Full=[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457821}; Flags: Fragment;"]
[10296,"'MAEA'",1460,1159,1309.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0034657///GID complex+++GO:0005826///actomyosin contractile ring+++GO:0005887///integral component of plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0016363///nuclear matrix","GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0003779///actin binding","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045721///negative regulation of gluconeogenesis+++GO:0043066///negative regulation of apoptotic process+++GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0048821///erythrocyte development+++GO:0043249///erythrocyte maturation+++GO:0033033///negative regulation of myeloid cell apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0048822///enucleate erythrocyte development+++GO:0007346///regulation of mitotic cell cycle+++GO:0007155///cell adhesion","IPR006595///CTLH, C-terminal LisH motif+++IPR006594///LIS1 homology motif+++IPR024964///CTLH/CRA C-terminal to LisH motif domain+++IPR013144///CRA domain+++IPR027714///Protein Fyv10/Macrophage erythroblast attacher","[MAEA_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein transferase MAEA; EC=2.3.2.27 {ECO:0000269|PubMed:29911972}; AltName: Full=Cell proliferation-inducing gene 5 protein {ECO:0000303|Ref.1}; AltName: Full=Erythroblast macrophage protein {ECO:0000303|PubMed:9763581}; AltName: Full=Human lung cancer oncogene 10 protein; Short=HLC-10; AltName: Full=Macrophage erythroblast attacher; AltName: Full=P44EMLP {ECO:0000303|PubMed:17467196};+++[B3KRN7_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_c {ECO:0000313|EMBL:EAW82589.1}; SubName: Full=cDNA FLJ34632 fis, clone KIDNE2015660, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG52449.1};+++[B4DJP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54833, moderately similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG58910.1};+++[B4DQT1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000424436}; SubName: Full=cDNA FLJ53639, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61043.1};+++[B4DVN3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000426807}; SubName: Full=cDNA FLJ54556, highly similar to Homo sapiens macrophage erythroblast attacher (MAEA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62745.1};+++[D3DVP1_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_b {ECO:0000313|EMBL:EAW82591.1};+++[D3DVP3_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_a {ECO:0000313|EMBL:EAW82588.1};+++[D3DVP6_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher, isoform CRA_d {ECO:0000313|EMBL:EAW82592.1};+++[D6R8Z3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422235};+++[D6RA86_HUMAN|Unreviewed]SubName: Full=Macrophage erythroblast attacher {ECO:0000313|Ensembl:ENSP00000423056};+++[D6RDW4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426966};+++[D6RE80_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000426903}; Flags: Fragment;+++[D6REW7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000421644}; Flags: Fragment;+++[D6RIB6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427512};+++[D6RID6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000427460}; Flags: Fragment;+++[E7ESC7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein transferase MAEA {ECO:0000313|Ensembl:ENSP00000422215};"]
[10297,"'APC2'",97,122,109.5,"05224///Breast cancer+++04390///Hippo signaling pathway+++05226///Gastric cancer+++05217///Basal cell carcinoma+++05213///Endometrial cancer+++05200///Pathways in cancer+++04934///Cushing's syndrome+++04810///Regulation of actin cytoskeleton+++05206///MicroRNAs in cancer+++04310///Wnt signaling pathway+++05165///Human papillomavirus infection+++05166///HTLV-I infection+++04550///Signaling pathways regulating pluripotency of stem cells+++05210///Colorectal cancer+++05225///Hepatocellular carcinoma","H02049///Bilateral macronodular adrenal hyperplasia (BMAH)+++H00017///Esophageal cancer+++H00020///Colorectal cancer+++H00044///Cancer of the anal canal+++H01431///Cushing's syndrome+++H01667///Medulloblastoma+++H01025///Familial adenomatous polyposis+++H00018///Gastric cancer+++H00047///Gallbladder cancer",null,null,"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030496///midbody+++GO:0015630///microtubule cytoskeleton+++GO:0031258///lamellipodium membrane+++GO:0005884///actin filament+++GO:0045171///intercellular bridge+++GO:0005874///microtubule+++GO:0005829///cytosol+++GO:0016342///catenin complex+++GO:0016020///membrane","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0008017///microtubule binding+++GO:0008013///beta-catenin binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000028///ribosomal small subunit assembly+++GO:0006412///translation+++GO:0090630///activation of GTPase activity+++GO:0006413///translational initiation+++GO:0000226///microtubule cytoskeleton organization+++GO:0006364///rRNA processing+++GO:0001649///osteoblast differentiation+++GO:0016055///Wnt signaling pathway+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0042274///ribosomal small subunit biogenesis","IPR026818///Adenomatous polyposis coli (APC)  family+++IPR026837///Adenomatous polyposis coli 2+++IPR009224///SAMP+++IPR009223///Adenomatous polyposis coli protein repeat+++IPR036149///APC, N-terminal coiled-coil domain superfamily+++IPR026831///Adenomatous polyposis coli protein+++IPR032038///Adenomatous polyposis coli, N-terminal dimerisation domain+++IPR009234///Adenomatous polyposis coli protein basic domain+++IPR011989///Armadillo-like helical+++IPR000225///Armadillo+++IPR016024///Armadillo-type fold","[APCL_HUMAN|Reviewed]RecName: Full=Adenomatous polyposis coli protein 2; AltName: Full=Adenomatous polyposis coli protein-like; Short=APC-like;"]
[10298,"'PAK4'",2078,1769,1923.5,"04510///Focal adhesion+++04810///Regulation of actin cytoskeleton+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++04012///ErbB signaling pathway+++04360///Axon guidance+++04660///T cell receptor signaling pathway+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005925///focal adhesion+++GO:0005913///cell-cell adherens junction+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0048365///Rac GTPase binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity","GO:0007010///cytoskeleton organization+++GO:0007049///cell cycle+++GO:0045766///positive regulation of angiogenesis+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0001558///regulation of cell growth+++GO:0006915///apoptotic process+++GO:0006468///protein phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0071407///cellular response to organic cyclic compound+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0060996///dendritic spine development+++GO:0023014///signal transduction by protein phosphorylation+++GO:0098609///cell-cell adhesion+++GO:0016477///cell migration+++GO:0043408///regulation of MAPK cascade+++GO:0016310///phosphorylation","IPR000719///Protein kinase domain+++IPR036936///CRIB domain superfamily+++IPR033923///p21 activated kinase binding domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR000095///CRIB domain","[PAK4_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 4; EC=2.7.11.1; AltName: Full=p21-activated kinase 4; Short=PAK-4;+++[A0A024R0J1_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[A0A024R0L8_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[B4DUG0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61413, highly similar to Serine/threonine-protein kinase PAK 4 {ECO:0000313|EMBL:BAG62322.1}; SubName: Full=p21(CDKN1A)-activated kinase 4, isoform CRA_e {ECO:0000313|EMBL:EAW56865.1};+++[M0R0L9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000471318}; Flags: Fragment;+++[M0R1R1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472061}; Flags: Fragment;+++[M0R2X4_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000472862}; Flags: Fragment;+++[M0R3G6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase PAK 4 {ECO:0000313|Ensembl:ENSP00000473215}; Flags: Fragment;"]
[10299,"'MARCH6'",1072,1357,1214.5,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0000835///ER ubiquitin ligase complex+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0008270///zinc ion binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0061630///ubiquitin protein ligase activity","GO:0016567///protein ubiquitination+++GO:0070936///protein K48-linked ubiquitination+++GO:0010498///proteasomal protein catabolic process+++GO:0036503///ERAD pathway+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:1904380///endoplasmic reticulum mannose trimming","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR011016///Zinc finger, RING-CH-type","[MARH6_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MARCH6; EC=2.3.2.27; AltName: Full=Doa10 homolog; AltName: Full=Membrane-associated RING finger protein 6; AltName: Full=Membrane-associated RING-CH protein VI; Short=MARCH-VI; AltName: Full=Protein TEB-4; AltName: Full=RING finger protein 176; AltName: Full=RING-type E3 ubiquitin transferase MARCH6 {ECO:0000305};+++[A0A0B4J206_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000424512};+++[D6RHY7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MARCH6 {ECO:0000313|Ensembl:ENSP00000426000};"]
[103,"'ADAR'",3231,4483.05,3857.025,"05162///Measles+++05164///Influenza A+++04623///Cytosolic DNA-sensing pathway","H00880///Dyschromatosis symmetrica hereditaria",null,null,"GO:0005634///nucleus+++GO:0044530///supraspliceosomal complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0004000///adenosine deaminase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0003677///DNA binding+++GO:0003725///double-stranded RNA binding","GO:0006397///mRNA processing+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0016553///base conversion or substitution editing+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0006611///protein export from nucleus+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006396///RNA processing+++GO:0006606///protein import into nucleus+++GO:0006382///adenosine to inosine editing+++GO:0009615///response to virus+++GO:0035455///response to interferon-alpha+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060337///type I interferon signaling pathway+++GO:0031054///pre-miRNA processing+++GO:0031047///gene silencing by RNA","IPR002466///Adenosine deaminase/editase+++IPR000607///Double-stranded RNA-specific adenosine deaminase (DRADA)+++IPR014720///Double-stranded RNA-binding domain+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR036388///Winged helix-like DNA-binding domain superfamily","[DSRAD_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific adenosine deaminase; Short=DRADA {ECO:0000303|PubMed:7972084}; EC=3.5.4.37 {ECO:0000269|PubMed:7565688, ECO:0000269|PubMed:7972084}; AltName: Full=136 kDa double-stranded RNA-binding protein; Short=p136; AltName: Full=Interferon-inducible protein 4; Short=IFI-4; AltName: Full=K88DSRBP;+++[A2IBT1_HUMAN|Unreviewed]SubName: Full=Truncated adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73519.1};+++[A2IBT2_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase acting on RNA 1-A {ECO:0000313|EMBL:ABM73520.1}; Flags: Fragment;+++[D3DV75_HUMAN|Unreviewed]SubName: Full=Adenosine deaminase, RNA-specific, isoform CRA_b {ECO:0000313|EMBL:EAW53189.1};+++[H0YCK3_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific adenosine deaminase {ECO:0000313|Ensembl:ENSP00000431794}; Flags: Fragment;"]
[1030,"'CDKN2B'",9164,11487,10325.5,"04934///Cushing's syndrome+++04110///Cell cycle+++05200///Pathways in cancer+++05203///Viral carcinogenesis+++05166///HTLV-I infection+++04068///FoxO signaling pathway+++05226///Gastric cancer+++05222///Small cell lung cancer+++04350///TGF-beta signaling pathway+++04218///Cellular senescence","H00015///Malignant pleural mesothelioma+++H01463///Mycosis fungoides+++H00036///Osteosarcoma+++H00409///Type II diabetes mellitus+++H01556///Meningioma",null,null,"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0016301///kinase activity","GO:0030219///megakaryocyte differentiation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0031668///cellular response to extracellular stimulus+++GO:0016310///phosphorylation+++GO:0090398///cellular senescence+++GO:0007093///mitotic cell cycle checkpoint+++GO:0008285///negative regulation of cell proliferation+++GO:0048536///spleen development+++GO:0031670///cellular response to nutrient+++GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0042326///negative regulation of phosphorylation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway","IPR036770///Ankyrin repeat-containing domain superfamily+++IPR020683///Ankyrin repeat-containing domain","[CDN2B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor B; AltName: Full=Multiple tumor suppressor 2; Short=MTS-2; AltName: Full=p14-INK4b; AltName: Full=p15-INK4b; Short=p15INK4B;+++[K7PPU3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AFN61601.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2B (P15, inhibits CDK4), isoform CRA_b {ECO:0000313|EMBL:EAW58597.1}; SubName: Full=p15 {ECO:0000313|EMBL:AGC10270.1};+++[Q5ZEY8_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:CAH59951.1};+++[Q8NIA6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2B {ECO:0000313|EMBL:AAF28397.1}; Flags: Fragment;"]
[10300,"'KATNB1'",800,596,698,null,"H00268///Lissencephaly (LIS)",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0030426///growth cone+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0030496///midbody+++GO:0005819///spindle+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0008352///katanin complex+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0030424///axon","GO:0008017///microtubule binding+++GO:0008568///microtubule-severing ATPase activity+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0070840///dynein complex binding","GO:0051301///cell division+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0010942///positive regulation of cell death+++GO:0007019///microtubule depolymerization+++GO:0007049///cell cycle+++GO:0031117///positive regulation of microtubule depolymerization+++GO:0051013///microtubule severing+++GO:0006605///protein targeting+++GO:0010976///positive regulation of neuron projection development","IPR017986///WD40-repeat-containing domain+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR001680///WD40 repeat+++IPR019775///WD40 repeat, conserved site+++IPR020472///G-protein beta WD-40 repeat+++IPR028021///Katanin p80 subunit, C-terminal+++IPR026962///Katanin p80 subunit B1","[KTNB1_HUMAN|Reviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000255|HAMAP-Rule:MF_03022};+++[A0A024R6U1_HUMAN|Unreviewed]RecName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; Short=Katanin p80 subunit B1 {ECO:0000256|HAMAP-Rule:MF_03022}; AltName: Full=p80 katanin {ECO:0000256|HAMAP-Rule:MF_03022};+++[H3BPD8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455270}; Flags: Fragment;+++[H3BPK1_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000455350}; Flags: Fragment;+++[H3BT67_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457046}; Flags: Fragment;+++[H3BTU7_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457334}; Flags: Fragment;+++[H3BTV8_HUMAN|Unreviewed]SubName: Full=Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000313|Ensembl:ENSP00000457347}; Flags: Fragment;"]
[10302,"'SNAPC5'",86,53,69.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0006355///regulation of transcription, DNA-templated","IPR029138///snRNA-activating protein complex subunit 5","[SNPC5_HUMAN|Reviewed]RecName: Full=snRNA-activating protein complex subunit 5; Short=SNAPc subunit 5; AltName: Full=Small nuclear RNA-activating complex polypeptide 5; AltName: Full=snRNA-activating protein complex 19 kDa subunit; Short=SNAPc 19 kDa subunit;+++[A0A024R5X1_HUMAN|Unreviewed]SubName: Full=Small nuclear RNA activating complex, polypeptide 5, 19kDa, isoform CRA_a {ECO:0000313|EMBL:EAW77772.1};+++[H3BQA0_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000455680};+++[H3BSI3_HUMAN|Unreviewed]SubName: Full=snRNA-activating protein complex subunit 5 {ECO:0000313|Ensembl:ENSP00000456716};"]
[10307,"'APBB3'",160,170,165,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0008134///transcription factor binding","GO:0006355///regulation of transcription, DNA-templated","IPR001202///WW domain+++IPR006020///PTB/PI domain+++IPR039576///Fe65+++IPR011993///PH-like domain superfamily+++IPR036020///WW domain superfamily","[APBB3_HUMAN|Reviewed]RecName: Full=Amyloid-beta A4 precursor protein-binding family B member 3; AltName: Full=Protein Fe65-like 2; Short=Fe65L2;+++[B3KQG2_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3, isoform CRA_b {ECO:0000313|EMBL:EAW62042.1}; SubName: Full=cDNA FLJ43254 fis, clone HEART2008108, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG54172.1}; SubName: Full=cDNA FLJ90404 fis, clone NT2RP2006092, highly similar to Amyloid beta A4 protein-binding family B member 3 (Fe65-like protein 2) (Fe65L2) {ECO:0000313|EMBL:BAG52024.1};+++[D6RBA1_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000424317};+++[D6RJB2_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000427272};+++[E7EX91_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family B member 3 {ECO:0000313|Ensembl:ENSP00000351389};+++[Q59EH2_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein-binding, family B, member 3 isoform b variant {ECO:0000313|EMBL:BAD93076.1}; Flags: Fragment;+++[Q86Z13_HUMAN|Unreviewed]SubName: Full=Fe65L2 isoform 339 {ECO:0000313|EMBL:BAC56948.1};+++[Q96DX9_HUMAN|Unreviewed]SubName: Full=Amyloid beta (A4) protein-binding, family B, member 3 {ECO:0000313|EMBL:AAH13158.1};"]
[10308,"'ZNF267'",66,40,53,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0006357///regulation of transcription by RNA polymerase II","IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily","[ZN267_HUMAN|Reviewed]RecName: Full=Zinc finger protein 267; AltName: Full=Zinc finger protein HZF2;+++[H3BMG2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454369}; Flags: Fragment;+++[H3BNA3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000454753}; Flags: Fragment;+++[H3BPW2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000455493}; Flags: Fragment;+++[I3L4I6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 267 {ECO:0000313|Ensembl:ENSP00000461286};"]
[10309,"'CCNO'",60,65,62.5,null,"H00564///Primary ciliary dyskinesia",null,null,"GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019901///protein kinase binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0004672///protein kinase activity","GO:0045787///positive regulation of cell cycle+++GO:0060271///cilium assembly+++GO:0000278///mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0042493///response to drug+++GO:1903251///multi-ciliated epithelial cell differentiation+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0006468///protein phosphorylation+++GO:0030030///cell projection organization+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division","IPR006671///Cyclin, N-terminal+++IPR036915///Cyclin-like superfamily+++IPR028864///Cyclin-O+++IPR013763///Cyclin-like+++IPR039361///Cyclin+++IPR004367///Cyclin, C-terminal domain","[CCNO_HUMAN|Reviewed]RecName: Full=Cyclin-O;"]
[1031,"'CDKN2C'",7,4,5.5,"01522///Endocrine resistance+++04934///Cushing's syndrome+++04110///Cell cycle+++05202///Transcriptional misregulation in cancer+++05166///HTLV-I infection",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0019901///protein kinase binding","GO:0016310///phosphorylation+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0030308///negative regulation of cell growth+++GO:0042326///negative regulation of phosphorylation+++GO:0007049///cell cycle+++GO:0048709///oligodendrocyte differentiation+++GO:0007050///cell cycle arrest+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0008285///negative regulation of cell proliferation","IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR020683///Ankyrin repeat-containing domain","[CDN2C_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor C; AltName: Full=Cyclin-dependent kinase 6 inhibitor; AltName: Full=p18-INK4c; AltName: Full=p18-INK6;+++[Q6ICV4_HUMAN|Unreviewed]SubName: Full=CDKN2C protein {ECO:0000313|EMBL:CAG29285.1}; SubName: Full=Cyclin-dependent kinase inhibitor 2C (P18, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAX06833.1}; SubName: Full=cDNA FLJ33851 fis, clone CTONG2005635, highly similar to CYCLIN-DEPENDENT KINASE 6 INHIBITOR {ECO:0000313|EMBL:BAG52297.1}; Flags: Fragment;+++[Q9P1T2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2C {ECO:0000313|EMBL:AAF28398.1}; Flags: Fragment;"]
[10311,"'VPS26C'",437,382,409.5,{"$nulls":4},"GO:0005768///endosome+++GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0008565///protein transporter activity","GO:0008150///biological_process+++GO:0006886///intracellular protein transport","IPR028934///Vacuolar protein sorting protein 26 related+++IPR014756///Immunoglobulin E-set+++IPR014752///Arrestin, C-terminal","[DSCR3_HUMAN|Reviewed]RecName: Full=Down syndrome critical region protein 3; AltName: Full=Down syndrome critical region protein A;+++[A8MTY9_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381964};+++[A8MY26_HUMAN|Unreviewed]SubName: Full=VPS26 endosomal protein sorting factor C {ECO:0000313|Ensembl:ENSP00000381967}; SubName: Full=cDNA FLJ53689, highly similar to Down syndrome critical region protein 3 {ECO:0000313|EMBL:BAH14000.1};"]
[10312,"'TCIRG1'",425,381,403,"04721///Synaptic vesicle cycle+++05323///Rheumatoid arthritis+++05152///Tuberculosis+++04145///Phagosome+++05120///Epithelial cell signaling in Helicobacter pylori infection+++04142///Lysosome+++00190///Oxidative phosphorylation+++04966///Collecting duct acid secretion+++01100///Metabolic pathways+++05110///Vibrio cholerae infection+++05165///Human papillomavirus infection","H00557///Cutis laxa+++H00428///Distal renal tubular acidosis (RTA type 1)+++H00436///Osteopetrosis","M00160///V-type ATPase, eukaryotes",null,"GO:0033179///proton-transporting V-type ATPase, V0 domain+++GO:0005886///plasma membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0016324///apical plasma membrane+++GO:0016020///membrane+++GO:0000220///vacuolar proton-transporting V-type ATPase, V0 domain+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0030670///phagocytic vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0010008///endosome membrane+++GO:0005765///lysosomal membrane","GO:0051117///ATPase binding+++GO:0005215///transporter activity+++GO:0015078///proton transmembrane transporter activity+++GO:0046961///proton-transporting ATPase activity, rotational mechanism","GO:0007035///vacuolar acidification+++GO:0006811///ion transport+++GO:0016236///macroautophagy+++GO:1902600///proton transmembrane transport+++GO:0006968///cellular defense response+++GO:0033572///transferrin transport+++GO:0034220///ion transmembrane transport+++GO:0007039///protein catabolic process in the vacuole+++GO:0043312///neutrophil degranulation+++GO:0008284///positive regulation of cell proliferation+++GO:0008286///insulin receptor signaling pathway+++GO:0015991///ATP hydrolysis coupled proton transport","IPR002490///V-type  ATPase, V0 complex, 116kDa subunit family+++IPR026028///ATPase, V0 complex, subunit 116kDa, eukaryotic","[VPP3_HUMAN|Reviewed]RecName: Full=V-type proton ATPase 116 kDa subunit a isoform 3; Short=V-ATPase 116 kDa isoform a3; AltName: Full=Osteoclastic proton pump 116 kDa subunit; Short=OC-116 kDa; Short=OC116; AltName: Full=T-cell immune regulator 1; AltName: Full=T-cell immune response cDNA7 protein; Short=TIRC7; AltName: Full=Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3;+++[A0A024R5E5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PM12_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[E9PMC5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};+++[E9PNA6_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YCE3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[H0YEL3_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q64F87_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN4_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 8 {ECO:0000313|EMBL:AAS59838.1}; Flags: Fragment;+++[Q6QBN5_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN6_HUMAN|Unreviewed]SubName: Full=T-cell immune regulator 1 transcript variant 6 {ECO:0000313|EMBL:AAS59836.1}; Flags: Fragment;+++[Q6QBN7_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q6QBN8_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;+++[Q8TCH1_HUMAN|Unreviewed]RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189}; Flags: Fragment;"]
[10313,"'RTN3'",1646,1896,1771,"05010///Alzheimer's disease",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0071786///endoplasmic reticulum tubular network organization+++GO:0071787///endoplasmic reticulum tubular network formation+++GO:0016032///viral process+++GO:0016192///vesicle-mediated transport+++GO:0006915///apoptotic process","IPR003388///Reticulon","[RTN3_HUMAN|Reviewed]RecName: Full=Reticulon-3; AltName: Full=Homolog of ASY protein; Short=HAP; AltName: Full=Neuroendocrine-specific protein-like 2; Short=NSP-like protein 2; AltName: Full=Neuroendocrine-specific protein-like II; Short=NSP-like protein II; Short=NSPLII;+++[A0A024R5C4_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[B7Z4M1_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[F5GWG7_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000441614}; Flags: Fragment;+++[F5H617_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[F5H891_HUMAN|Unreviewed]SubName: Full=Reticulon-3 {ECO:0000313|Ensembl:ENSP00000442080}; Flags: Fragment;+++[Q7RTN4_HUMAN|Unreviewed]SubName: Full=Truncated RTN3-A3 {ECO:0000313|EMBL:DAA01930.1};"]
[10314,"'LANCL1'",442,514,478,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0050750///low-density lipoprotein particle receptor binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0017124///SH3 domain binding+++GO:0008270///zinc ion binding+++GO:0043295///glutathione binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway","IPR007822///Lanthionine synthetase C-like+++IPR012341///Six-hairpin glycosidase-like superfamily+++IPR020464///LanC-like protein, eukaryotic","[LANC1_HUMAN|Reviewed]RecName: Full=LanC-like protein 1; AltName: Full=40 kDa erythrocyte membrane protein; Short=p40;+++[A0A024R3Z5_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_b {ECO:0000313|EMBL:EAW70491.1};+++[B2R602_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92709, highly similar to Homo sapiens LanC lantibiotic synthetase component C-like 1 (bacterial) (LANCL1), mRNA {ECO:0000313|EMBL:BAG35299.1};+++[E9PHS0_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000396518}; Flags: Fragment;+++[F8WDS9_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000395442};+++[H7C2E3_HUMAN|Unreviewed]SubName: Full=LanC-like protein 1 {ECO:0000313|Ensembl:ENSP00000405364}; Flags: Fragment;+++[Q53TN2_HUMAN|Unreviewed]SubName: Full=LanC lantibiotic synthetase component C-like 1 (Bacterial), isoform CRA_a {ECO:0000313|EMBL:EAW70487.1};+++[Q6FHH6_HUMAN|Unreviewed]SubName: Full=LANCL1 protein {ECO:0000313|EMBL:CAG46576.1}; Flags: Fragment;"]
[10316,"'NMUR1'",0,1,0.5,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity+++GO:0008188///neuropeptide receptor activity+++GO:0001607///neuromedin U receptor activity+++GO:0042924///neuromedin U binding","GO:0007202///activation of phospholipase C activity+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006816///calcium ion transport+++GO:0007165///signal transduction+++GO:0048016///inositol phosphate-mediated signaling+++GO:0006939///smooth muscle contraction+++GO:0019722///calcium-mediated signaling+++GO:0007218///neuropeptide signaling pathway+++GO:0006821///chloride transport","IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR005390///Neuromedin U receptor+++IPR017452///GPCR, rhodopsin-like, 7TM+++IPR005391///Neuromedin U receptor, type 1","[NMUR1_HUMAN|Reviewed]RecName: Full=Neuromedin-U receptor 1; Short=NMU-R1; AltName: Full=G-protein coupled receptor 66; AltName: Full=G-protein coupled receptor FM-3;+++[L8E9D8_HUMAN|Unreviewed]SubName: Full=Alternative protein NMUR1 {ECO:0000313|EMBL:CCQ43346.1};"]
[10317,"'B3GALT5'",12,11,11.5,"01100///Metabolic pathways+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series",null,"M00070///Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer","R05964///UDP-D-galactose + Globoside <=> UDP + Galactosylgloboside+++R06006///UDP-D-galactose + Lc3Cer <=> UDP + Lc4Cer","GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity+++GO:0008378///galactosyltransferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity","GO:0009312///oligosaccharide biosynthetic process+++GO:0006487///protein N-linked glycosylation+++GO:0006486///protein glycosylation+++GO:0009617///response to bacterium","IPR002659///Glycosyl transferase, family 31","[B3GT5_HUMAN|Reviewed]RecName: Full=Beta-1,3-galactosyltransferase 5; Short=Beta-1,3-GalTase 5; Short=Beta3Gal-T5; Short=Beta3GalT5; Short=b3Gal-T5; EC=2.4.1.-; AltName: Full=Beta-3-Gx-T5; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5;+++[A0A0A0MS93_HUMAN|Unreviewed]RecName: Full=Hexosyltransferase {ECO:0000256|RuleBase:RU363063}; EC=2.4.1.- {ECO:0000256|RuleBase:RU363063};"]
[10318,"'TNIP1'",2019,1668,1843.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005622///intracellular+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0070034///telomerase RNA binding+++GO:0005515///protein binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0003723///RNA binding","GO:0043489///RNA stabilization+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0051973///positive regulation of telomerase activity+++GO:0000454///snoRNA guided rRNA pseudouridine synthesis+++GO:0050727///regulation of inflammatory response+++GO:0006364///rRNA processing+++GO:1904358///positive regulation of telomere maintenance via telomere lengthening+++GO:0042254///ribosome biogenesis+++GO:0045071///negative regulation of viral genome replication+++GO:0006954///inflammatory response+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0000493///box H/ACA snoRNP assembly+++GO:0001522///pseudouridine synthesis+++GO:0009101///glycoprotein biosynthetic process+++GO:1903003///positive regulation of protein deubiquitination+++GO:0007159///leukocyte cell-cell adhesion+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0085032///modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade+++GO:0006952///defense response+++GO:1905323///telomerase holoenzyme complex assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090669///telomerase RNA stabilization+++GO:0050729///positive regulation of inflammatory response+++GO:0006412///translation+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016579///protein deubiquitination","IPR033372///TNFAIP3-interacting protein 1","[TNIP1_HUMAN|Reviewed]RecName: Full=TNFAIP3-interacting protein 1; AltName: Full=A20-binding inhibitor of NF-kappa-B activation 1; Short=ABIN-1; AltName: Full=HIV-1 Nef-interacting protein; AltName: Full=Nef-associated factor 1; Short=Naf1; AltName: Full=Nip40-1; AltName: Full=Virion-associated nuclear shuttling protein; Short=VAN; Short=hVAN;+++[A0A0A0MRZ4_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000374029};+++[A8K4N4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77844, highly similar to Homo sapiens TNFAIP3 interacting protein 1, mRNA {ECO:0000313|EMBL:BAF83688.1};+++[B7Z8K2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61022, highly similar to Nef-associated factor 1 {ECO:0000313|EMBL:BAH13988.1};+++[E7EMV7_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427854};+++[E7EW15_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428487}; Flags: Fragment;+++[E7EW68_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430279}; Flags: Fragment;+++[E7EWG2_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000428404}; Flags: Fragment;+++[H0YC17_HUMAN|Unreviewed]SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000430739}; Flags: Fragment;"]
[10319,"'LAMC3'",6,7,6.5,"05146///Amoebiasis+++04151///PI3K-Akt signaling pathway+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05145///Toxoplasmosis+++05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04510///Focal adhesion",{"$nulls":3},"GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005604///basement membrane","GO:0005198///structural molecule activity","GO:0030198///extracellular matrix organization+++GO:0007155///cell adhesion+++GO:0007601///visual perception+++GO:0060041///retina development in camera-type eye+++GO:0000904///cell morphogenesis involved in differentiation+++GO:0014002///astrocyte development","IPR002049///Laminin EGF domain+++IPR000034///Laminin IV+++IPR008211///Laminin, N-terminal+++IPR038684///Laminin, N-terminal domain superfamily+++IPR000742///EGF-like domain","[LAMC3_HUMAN|Reviewed]RecName: Full=Laminin subunit gamma-3; AltName: Full=Laminin-12 subunit gamma; AltName: Full=Laminin-14 subunit gamma; AltName: Full=Laminin-15 subunit gamma; Flags: Precursor;+++[H7BY04_HUMAN|Unreviewed]SubName: Full=Laminin subunit gamma-3 {ECO:0000313|Ensembl:ENSP00000347627}; Flags: Fragment;+++[Q8N2D6_HUMAN|Unreviewed]SubName: Full=cDNA PSEC0236 fis, clone HEMBA1007104, highly similar to Laminin gamma-3 chain {ECO:0000313|EMBL:BAC11679.1};"]
[1032,"'CDKN2D'",49,43,46,"04068///FoxO signaling pathway+++04110///Cell cycle",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0097129///cyclin D2-CDK4 complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding","GO:0009411///response to UV+++GO:0033280///response to vitamin D+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0007605///sensory perception of sound+++GO:0042326///negative regulation of phosphorylation+++GO:0030308///negative regulation of cell growth+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0007050///cell cycle arrest+++GO:0032526///response to retinoic acid+++GO:1902807///negative regulation of cell cycle G1/S phase transition+++GO:0007049///cell cycle+++GO:0048102///autophagic cell death+++GO:0008285///negative regulation of cell proliferation+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","IPR002110///Ankyrin repeat+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily","[CDN2D_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 4 inhibitor D; AltName: Full=p19-INK4d;+++[A0A024R796_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 2D (P19, inhibits CDK4), isoform CRA_a {ECO:0000313|EMBL:EAW84123.1};"]
[10322,"'SMYD5'",448,444.34,446.17,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0032259///methylation+++GO:0008150///biological_process","IPR001214///SET domain","[SMYD5_HUMAN|Reviewed]RecName: Full=SET and MYND domain-containing protein 5; EC=2.1.1.-; AltName: Full=Protein NN8-4AG; AltName: Full=Retinoic acid-induced protein 15;+++[C9IYN9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000412587}; Flags: Fragment;+++[E2QRN5_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000258100};+++[F8WEJ9_HUMAN|Unreviewed]SubName: Full=SET and MYND domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000388195};"]
[10324,"'KLHL41'",3,2,2.5,null,"H00698///Nemaline myopathy",null,null,"GO:0016529///sarcoplasmic reticulum+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031143///pseudopodium+++GO:0001726///ruffle+++GO:0031430///M band+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0035914///skeletal muscle cell differentiation+++GO:2000291///regulation of myoblast proliferation+++GO:0048741///skeletal muscle fiber development+++GO:0006941///striated muscle contraction+++GO:0030239///myofibril assembly+++GO:0045214///sarcomere organization+++GO:0043687///post-translational protein modification+++GO:0031275///regulation of lateral pseudopodium assembly+++GO:0045661///regulation of myoblast differentiation+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0016567///protein ubiquitination","IPR000210///BTB/POZ domain+++IPR015915///Kelch-type beta propeller+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR030571///Kelch-like protein 41+++IPR011705///BTB/Kelch-associated+++IPR006652///Kelch repeat type 1+++IPR017096///BTB-kelch protein","[KLH41_HUMAN|Reviewed]RecName: Full=Kelch-like protein 41; AltName: Full=Kel-like protein 23; AltName: Full=Kelch repeat and BTB domain-containing protein 10; AltName: Full=Kelch-related protein 1; AltName: Full=Sarcosin;+++[Q3ZTS6_HUMAN|Unreviewed]SubName: Full=Sarcomeric muscle protein {ECO:0000313|EMBL:AAQ76811.1}; Flags: Fragment;"]
[10325,"'RRAGB'",227.69,247.12,237.405,"04140///Autophagy - animal+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0034448///EGO complex+++GO:1990131///Gtr1-Gtr2 GTPase complex+++GO:0005765///lysosomal membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0051020///GTPase binding+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0032561///guanyl ribonucleotide binding","GO:1904263///positive regulation of TORC1 signaling+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0071230///cellular response to amino acid stimulus+++GO:0007050///cell cycle arrest+++GO:0034198///cellular response to amino acid starvation+++GO:0009267///cellular response to starvation+++GO:0034613///cellular protein localization+++GO:0010506///regulation of autophagy+++GO:0032006///regulation of TOR signaling+++GO:1990253///cellular response to leucine starvation","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR006762///Gtr1/RagA G protein+++IPR039397///RagA/B","[RRAGB_HUMAN|Reviewed]RecName: Full=Ras-related GTP-binding protein B {ECO:0000305}; Short=Rag B {ECO:0000303|PubMed:11073942}; Short=RagB {ECO:0000303|PubMed:7499430};+++[Q5VZM0_HUMAN|Unreviewed]SubName: Full=Ras-related GTP-binding protein B {ECO:0000313|Ensembl:ENSP00000410630}; Flags: Fragment;"]
[10327,"'AKR1A1'",1111,756,933.5,"01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++00040///Pentose and glucuronate interconversions+++00561///Glycerolipid metabolism+++00930///Caprolactam degradation+++01130///Biosynthesis of antibiotics+++01220///Degradation of aromatic compounds+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis",null,"M00014///Glucuronate pathway (uronate pathway)","R01041///glycerol:NADP+ oxidoreductase   Glycerol + NADP+ <=> D-Glyceraldehyde + NADPH + H++++R05231///6-Hydroxyhexanoate:NADP+ oxidoreductase   6-Hydroxyhexanoic acid + NADP+ <=> Adipate semialdehyde + NADPH + H++++R00746///Ethanol:NADP+ oxidoreductase   Ethanol + NADP+ <=> Acetaldehyde + NADPH + H++++R01481///L-gulonate:NADP+ 6-oxidoreductase   L-Gulonate + NADP+ <=> D-Glucuronate + NADPH + H+","GO:0045202///synapse+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0009055///electron transfer activity+++GO:0004033///aldo-keto reductase (NADP) activity+++GO:0047939///L-glucuronate reductase activity+++GO:0016971///flavin-linked sulfhydryl oxidase activity+++GO:0005515///protein binding+++GO:0016972///thiol oxidase activity+++GO:0004032///alditol:NADP+ 1-oxidoreductase activity+++GO:0016491///oxidoreductase activity","GO:0042840///D-glucuronate catabolic process+++GO:0022900///electron transport chain+++GO:0006081///cellular aldehyde metabolic process+++GO:0019853///L-ascorbic acid biosynthetic process+++GO:1901687///glutathione derivative biosynthetic process+++GO:0006006///glucose metabolic process+++GO:0055114///oxidation-reduction process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0046185///aldehyde catabolic process","IPR036812///NADP-dependent oxidoreductase domain superfamily+++IPR020471///Aldo/keto reductase+++IPR023210///NADP-dependent oxidoreductase domain+++IPR018170///Aldo/keto reductase, conserved site","[AK1A1_HUMAN|Reviewed]RecName: Full=Alcohol dehydrogenase [NADP(+)]; EC=1.1.1.2; AltName: Full=Aldehyde reductase; AltName: Full=Aldo-keto reductase family 1 member A1;+++[Q5T621_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000398414}; Flags: Fragment;+++[Q9H2X5_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[Q9NY86_HUMAN|Unreviewed]RecName: Full=Sulfhydryl oxidase {ECO:0000256|RuleBase:RU371123}; EC=1.8.3.2 {ECO:0000256|RuleBase:RU371123};+++[V9GYG2_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476713};+++[V9GYP9_HUMAN|Unreviewed]SubName: Full=Alcohol dehydrogenase [NADP(+)] {ECO:0000313|Ensembl:ENSP00000476978}; Flags: Fragment;+++[V9HWI0_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 6 {ECO:0000313|EMBL:ACF94472.1}; SubName: Full=Epididymis secretory sperm binding protein Li 165mP {ECO:0000313|EMBL:ACJ13642.1};"]
[10328,"'EMC8'",322,284,303,"00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01100///Metabolic pathways+++05016///Huntington's disease+++04714///Thermogenesis+++04260///Cardiac muscle contraction+++05012///Parkinson's disease","H00920///Exocrine pancreatic insufficiency, dyserythropoietic anemia, and calvarial hyperostosis","M00154///Cytochrome c oxidase",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0072546///ER membrane protein complex","GO:0005515///protein binding",null,"IPR005366///ER membrane protein complex subunit 8/9+++IPR037518///MPN domain","[EMC8_HUMAN|Reviewed]RecName: Full=ER membrane protein complex subunit 8; AltName: Full=Neighbor of COX4; AltName: Full=Protein FAM158B;+++[M0R1B0_HUMAN|Unreviewed]SubName: Full=ER membrane protein complex subunit 8 {ECO:0000313|Ensembl:ENSP00000471751}; Flags: Fragment;+++[Q53Y03_HUMAN|Unreviewed]SubName: Full=COX4 neighbor, isoform CRA_a {ECO:0000313|EMBL:EAW95439.1}; SubName: Full=Neighbor of COX4 {ECO:0000313|EMBL:AAP35796.1}; SubName: Full=cDNA, FLJ94626, Homo sapiens neighbor of COX4 (NOC4), mRNA {ECO:0000313|EMBL:BAG36691.1};"]
[10329,"'RXYLT1'",127,116,121.5,"00515///Mannose type O-glycan biosynthesis+++01100///Metabolic pathways","H00120///Muscular dystrophy-dystroglycanopathy type A",null,null,"GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane","GO:0016740///transferase activity+++GO:0120053///ribitol beta-1,4-xylosyltransferase activity","GO:0035269///protein O-linked mannosylation+++GO:0006486///protein glycosylation",null,"[RXLT1_HUMAN|Reviewed]RecName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000305}; EC=2.4.2.- {ECO:0000269|PubMed:27733679}; AltName: Full=Transmembrane protein 5 {ECO:0000305}; AltName: Full=UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase {ECO:0000303|PubMed:27733679};+++[F5GXF8_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440845};+++[G3V1K2_HUMAN|Unreviewed]SubName: Full=Ribitol-5-phosphate xylosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000440280}; SubName: Full=Transmembrane protein 5, isoform CRA_a {ECO:0000313|EMBL:EAW97120.1};"]
[1033,"'CDKN3'",11,19,15,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity","GO:0006470///protein dephosphorylation+++GO:0007050///cell cycle arrest+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0007049///cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0016311///dephosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0000082///G1/S transition of mitotic cell cycle","IPR008425///Cyclin-dependent kinase inhibitor 3+++IPR003595///Protein-tyrosine phosphatase, catalytic+++IPR029021///Protein-tyrosine phosphatase-like+++IPR000387///Tyrosine specific protein phosphatases domain+++IPR022778///CDKN3 domain","[CDKN3_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=CDK2-associated dual-specificity phosphatase; AltName: Full=Cyclin-dependent kinase interactor 1; AltName: Full=Cyclin-dependent kinase-interacting protein 2; AltName: Full=Kinase-associated phosphatase;+++[A0A087WW25_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000479875};+++[A0A087WWK3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[A0A0S2KP18_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 splice variant {ECO:0000313|EMBL:ALO50058.1};+++[F5H232_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000445572};+++[F8WD24_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000378944};+++[G3V1K6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000313|Ensembl:ENSP00000440404};+++[G3V2J7_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};+++[H7C0S3_HUMAN|Unreviewed]RecName: Full=Cyclin-dependent kinase inhibitor 3 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR037322}; EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR037322};"]
[10330,"'CNPY2'",2445,1715,2080,{"$nulls":4},"GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0010988///regulation of low-density lipoprotein particle clearance+++GO:0010629///negative regulation of gene expression+++GO:0045716///positive regulation of low-density lipoprotein particle receptor biosynthetic process","IPR021852///Domain of unknown function DUF3456+++IPR008139///Saposin B type domain","[CNPY2_HUMAN|Reviewed]RecName: Full=Protein canopy homolog 2; AltName: Full=MIR-interacting saposin-like protein; AltName: Full=Putative secreted protein Zsig9; AltName: Full=Transmembrane protein 4; Flags: Precursor;+++[F8VXJ7_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448809}; Flags: Fragment;+++[F8W1K5_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000446784}; Flags: Fragment;+++[H0YI18_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000448333}; Flags: Fragment;+++[H0YIH9_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 2 {ECO:0000313|Ensembl:ENSP00000449444}; Flags: Fragment;"]
[10333,"'TLR6'",18.02,33.24,25.63,"04620///Toll-like receptor signaling pathway+++05152///Tuberculosis+++05142///Chagas disease (American trypanosomiasis)+++04145///Phagosome",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0035355///Toll-like receptor 2-Toll-like receptor 6 protein complex+++GO:0045121///membrane raft+++GO:0030670///phagocytic vesicle membrane+++GO:0005794///Golgi apparatus","GO:0035663///Toll-like receptor 2 binding+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0071723///lipopeptide binding+++GO:0038023///signaling receptor activity+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0038124///toll-like receptor TLR6:TLR2 signaling pathway+++GO:0002376///immune system process+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0032493///response to bacterial lipoprotein+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:0046209///nitric oxide metabolic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0043032///positive regulation of macrophage activation+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045410///positive regulation of interleukin-6 biosynthetic process+++GO:2000483///negative regulation of interleukin-8 secretion+++GO:0045087///innate immune response+++GO:0002224///toll-like receptor signaling pathway+++GO:0001775///cell activation+++GO:0042742///defense response to bacterium+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:1900227///positive regulation of NLRP3 inflammasome complex assembly+++GO:0034136///negative regulation of toll-like receptor 2 signaling pathway+++GO:1904646///cellular response to amyloid-beta+++GO:0140052///cellular response to oxidised low-density lipoprotein particle stimulus+++GO:0034150///toll-like receptor 6 signaling pathway+++GO:0006954///inflammatory response+++GO:0042496///detection of diacyl bacterial lipopeptide+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0010628///positive regulation of gene expression+++GO:0001774///microglial cell activation+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0050707///regulation of cytokine secretion+++GO:1903223///positive regulation of oxidative stress-induced neuron death+++GO:0050702///interleukin-1 beta secretion+++GO:0071726///cellular response to diacyl bacterial lipopeptide","IPR035897///Toll/interleukin-1 receptor homology (TIR) domain superfamily+++IPR001611///Leucine-rich repeat+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR027187///Toll-like receptor 6+++IPR000157///Toll/interleukin-1 receptor homology (TIR) domain+++IPR032675///Leucine-rich repeat domain superfamily+++IPR003591///Leucine-rich repeat, typical subtype","[TLR6_HUMAN|Reviewed]RecName: Full=Toll-like receptor 6; AltName: CD_antigen=CD286; Flags: Precursor;+++[B2R933_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH37_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH42_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH44_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6CH45_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[B6RFS7_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS91_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS92_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS93_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS96_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS97_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS98_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CS99_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D1CSA0_HUMAN|Unreviewed]RecName: Full=Toll-like receptor {ECO:0000256|RuleBase:RU363040};+++[D6R979_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000423326}; Flags: Fragment;+++[D6RAV7_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 6 {ECO:0000313|Ensembl:ENSP00000424718}; Flags: Fragment;"]
[10335,"'MRVI1'",74,151,112.5,"04270///Vascular smooth muscle contraction+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031095///platelet dense tubular network membrane","GO:0005515///protein binding",null,"IPR008677///MRVI1","[MRVI1_HUMAN|Reviewed]RecName: Full=Protein MRVI1; AltName: Full=Inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate; AltName: Full=JAW1-related protein MRVI1;+++[E9PJ61_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000435658};+++[E9PNK7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000434741};+++[E9PRG4_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432325}; Flags: Fragment;+++[E9PRH0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432312};+++[H0YCL0_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000431845}; Flags: Fragment;+++[H0YDM7_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000433970}; Flags: Fragment;+++[H0YI08_HUMAN|Unreviewed]SubName: Full=Protein MRVI1 {ECO:0000313|Ensembl:ENSP00000432067};"]
[10336,"'PCGF3'",762,770,766,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0035102///PRC1 complex+++GO:0005634///nucleus+++GO:0031519///PcG protein complex+++GO:0000805///X chromosome+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding","GO:0060819///inactivation of X chromosome by genetic imprinting+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036353///histone H2A-K119 monoubiquitination","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR032443///RAWUL domain+++IPR039642///E3 ubiquitin-protein ligase/polycomb group RING finger protein+++IPR001841///Zinc finger, RING-type+++IPR017907///Zinc finger, RING-type, conserved site","[PCGF3_HUMAN|Reviewed]RecName: Full=Polycomb group RING finger protein 3; AltName: Full=RING finger protein 3A;+++[A0A087WVH5_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000479441};+++[B3KQ06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32562 fis, clone SPLEN1000165, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG51868.1};+++[B3KWT8_HUMAN|Unreviewed]SubName: Full=Polycomb group ring finger 3, isoform CRA_b {ECO:0000313|EMBL:EAW82654.1}; SubName: Full=cDNA FLJ43813 fis, clone TESTI4001467, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG54250.1};+++[B4DTN5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54810, highly similar to Homo sapiens polycomb group ring finger 3 (PCGF3), mRNA {ECO:0000313|EMBL:BAG62047.1};+++[B5MEC4_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000383015};+++[C9J3G7_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000398493}; Flags: Fragment;+++[C9JGV3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000416279}; Flags: Fragment;+++[C9JYD0_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000401431}; Flags: Fragment;+++[F2Z3P3_HUMAN|Unreviewed]SubName: Full=Polycomb group RING finger protein 3 {ECO:0000313|Ensembl:ENSP00000405840};"]
[10342,"'TFG'",3911,3978,3944.5,"05200///Pathways in cancer+++05216///Thyroid cancer","H00266///Hereditary spastic paraplegia (SPG)+++H00032///Thyroid cancer",null,null,"GO:0070971///endoplasmic reticulum exit site+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport","IPR034857///TFG, PB1 domain+++IPR033512///Protein TFG+++IPR000270///PB1 domain","[TFG_HUMAN|Reviewed]RecName: Full=Protein TFG; AltName: Full=TRK-fused gene protein;+++[C9JJP5_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000420797}; Flags: Fragment;+++[C9JTY3_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419559}; Flags: Fragment;+++[C9JUE0_HUMAN|Unreviewed]SubName: Full=Protein TFG {ECO:0000313|Ensembl:ENSP00000419504}; Flags: Fragment;+++[Q05BK6_HUMAN|Unreviewed]SubName: Full=TFG protein {ECO:0000313|EMBL:AAH41600.1};"]
[10344,"'CCL26'",48,41,44.5,"04062///Chemokine signaling pathway+++04060///Cytokine-cytokine receptor interaction","H01361///Eosinophilic esophagitis+++H01360///Allergic rhinitis",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008009///chemokine activity+++GO:0005515///protein binding+++GO:0048018///receptor ligand activity+++GO:0048020///CCR chemokine receptor binding+++GO:0005125///cytokine activity+++GO:0031728///CCR3 chemokine receptor binding","GO:0043547///positive regulation of GTPase activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0048245///eosinophil chemotaxis+++GO:0006955///immune response+++GO:0071347///cellular response to interleukin-1+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0006954///inflammatory response+++GO:0048247///lymphocyte chemotaxis+++GO:0007267///cell-cell signaling+++GO:0070098///chemokine-mediated signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0050921///positive regulation of chemotaxis+++GO:0006935///chemotaxis+++GO:0071346///cellular response to interferon-gamma+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030593///neutrophil chemotaxis+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0010818///T cell chemotaxis+++GO:0002548///monocyte chemotaxis","IPR000827///CC chemokine, conserved site+++IPR039809///Chemokine beta/gamma/delta+++IPR001811///Chemokine interleukin-8-like domain+++IPR036048///Chemokine interleukin-8-like superfamily","[CCL26_HUMAN|Reviewed]RecName: Full=C-C motif chemokine 26; AltName: Full=CC chemokine IMAC; AltName: Full=Eotaxin-3; AltName: Full=Macrophage inflammatory protein 4-alpha; Short=MIP-4-alpha; AltName: Full=Small-inducible cytokine A26; AltName: Full=Thymic stroma chemokine-1; Short=TSC-1; Flags: Precursor;"]
[10345,"'TRDN'",4,7,5.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0030314///junctional membrane complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0014701///junctional sarcoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0030674///protein binding, bridging","GO:0006874///cellular calcium ion homeostasis+++GO:0034220///ion transmembrane transport+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0086036///regulation of cardiac muscle cell membrane potential+++GO:0090158///endoplasmic reticulum membrane organization+++GO:0006936///muscle contraction+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0010649///regulation of cell communication by electrical coupling+++GO:1903779///regulation of cardiac conduction+++GO:0060047///heart contraction+++GO:0009617///response to bacterium+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0031122///cytoplasmic microtubule organization+++GO:1901846///positive regulation of cell communication by electrical coupling involved in cardiac conduction","IPR010798///Triadin+++IPR007943///Aspartyl beta-hydroxylase/Triadin domain","[TRDN_HUMAN|Reviewed]RecName: Full=Triadin;+++[H0Y6P0_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000406768}; Flags: Fragment;+++[H7BY47_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000354307}; Flags: Fragment;+++[H9ME53_HUMAN|Unreviewed]SubName: Full=Cardiac triadin Trisk 32 isoform {ECO:0000313|EMBL:AEW10557.1}; SubName: Full=Triadin {ECO:0000313|Ensembl:ENSP00000439281};+++[Q05C44_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH29393.1}; Flags: Fragment;+++[Q6PG49_HUMAN|Unreviewed]SubName: Full=TRDN protein {ECO:0000313|EMBL:AAH57222.1}; Flags: Fragment;+++[Q8IVK2_HUMAN|Unreviewed]SubName: Full=Triadin {ECO:0000313|EMBL:CAD33526.2};"]
[10346,"'TRIM22'",1979,2345,2162,{"$nulls":4},"GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0015030///Cajal body+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0016740///transferase activity+++GO:0003714///transcription corepressor activity+++GO:0030674///protein binding, bridging+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0016032///viral process+++GO:0010508///positive regulation of autophagy+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0016567///protein ubiquitination+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0009615///response to virus+++GO:0032880///regulation of protein localization+++GO:0051607///defense response to virus+++GO:0070206///protein trimerization+++GO:0006955///immune response+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity","IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR003879///Butyrophylin-like, SPRY domain+++IPR027370///RING-type zinc-finger, LisH dimerisation motif+++IPR000315///B-box-type zinc finger+++IPR001870///B30.2/SPRY domain+++IPR001841///Zinc finger, RING-type+++IPR017907///Zinc finger, RING-type, conserved site+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR035827///TRIM22, PRY/SPRY domain+++IPR003877///SPRY domain","[TRI22_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM22; EC=2.3.2.27; AltName: Full=50 kDa-stimulated trans-acting factor; AltName: Full=RING finger protein 94; AltName: Full=RING-type E3 ubiquitin transferase TRIM22 {ECO:0000305}; AltName: Full=Staf-50; AltName: Full=Tripartite motif-containing protein 22;+++[B4DQS5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51049, highly similar to Tripartite motif-containing protein 22 {ECO:0000313|EMBL:BAG61037.1};+++[C9J060_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000400417}; Flags: Fragment;+++[C9JIU5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000396849}; Flags: Fragment;+++[C9JWC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000393250}; Flags: Fragment;+++[D3DQT0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_b {ECO:0000313|EMBL:EAW68770.1};+++[D3DQT1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 22, isoform CRA_a {ECO:0000313|EMBL:EAW68768.1};+++[H7BZD3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000388994}; Flags: Fragment;+++[H7C262_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000404204}; Flags: Fragment;+++[H7C2K0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000406412}; Flags: Fragment;+++[H7C376_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase TRIM22 {ECO:0000313|Ensembl:ENSP00000409991}; Flags: Fragment;+++[Q4A1P5_HUMAN|Unreviewed]SubName: Full=Tripartite binding motif 22 {ECO:0000313|EMBL:CAJ13842.1}; Flags: Fragment;"]
[10347,"'ABCA7'",282,339,310.5,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043190///ATP-binding cassette (ABC) transporter complex+++GO:0001891///phagocytic cup+++GO:0009986///cell surface+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0032587///ruffle membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus","GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0090556///phosphatidylserine-translocating ATPase activity+++GO:0034188///apolipoprotein A-I receptor activity+++GO:0005515///protein binding+++GO:0005319///lipid transporter activity+++GO:0090554///phosphatidylcholine-translocating ATPase activity+++GO:0000166///nucleotide binding+++GO:0005215///transporter activity+++GO:0016887///ATPase activity+++GO:0005524///ATP binding","GO:1902430///negative regulation of amyloid-beta formation+++GO:0033700///phospholipid efflux+++GO:0033344///cholesterol efflux+++GO:0050766///positive regulation of phagocytosis+++GO:0042985///negative regulation of amyloid precursor protein biosynthetic process+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0018149///peptide cross-linking+++GO:0055085///transmembrane transport+++GO:0010875///positive regulation of cholesterol efflux+++GO:1902995///positive regulation of phospholipid efflux+++GO:0038027///apolipoprotein A-I-mediated signaling pathway+++GO:0034380///high-density lipoprotein particle assembly+++GO:0034504///protein localization to nucleus+++GO:0006909///phagocytosis+++GO:0007613///memory+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:1901076///positive regulation of engulfment of apoptotic cell+++GO:0045332///phospholipid translocation+++GO:0006869///lipid transport","IPR026082///ABC transporter A+++IPR017871///ABC transporter, conserved site+++IPR003593///AAA+ ATPase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR030369///ATP-binding cassette subfamily A member 7+++IPR003439///ABC transporter-like","[ABCA7_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 7; AltName: Full=ABCA-SSN; AltName: Full=Autoantigen SS-N; AltName: Full=Macrophage ABC transporter;+++[A0A087WUR5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000478857}; Flags: Fragment;+++[A0A087WX86_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000480811}; Flags: Fragment;+++[A0A087WZX6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000482948}; Flags: Fragment;+++[B3KUJ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ40025 fis, clone STOMA2008050, highly similar to Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 7 (ABCA7), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG53455.1};+++[D6W5Y0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette, sub-family A (ABC1), member 7, isoform CRA_e {ECO:0000313|EMBL:EAW69563.1};+++[E9PKG5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000433545}; Flags: Fragment;+++[E9PL63_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000431473}; Flags: Fragment;+++[H0YCN5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000432031}; Flags: Fragment;+++[H0YF58_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 7 {ECO:0000313|Ensembl:ENSP00000437311}; Flags: Fragment;+++[L8EB07_HUMAN|Unreviewed]SubName: Full=Alternative protein ABCA7 {ECO:0000313|EMBL:CCQ43618.1};"]
[10349,"'ABCA10'",13,13,13,"02010///ABC transporters",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005319///lipid transporter activity+++GO:0016887///ATPase activity+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding","GO:0006869///lipid transport+++GO:0055085///transmembrane transport","IPR003439///ABC transporter-like+++IPR026082///ABC transporter A+++IPR003593///AAA+ ATPase domain+++IPR017871///ABC transporter, conserved site+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[ABCAA_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 10;+++[E5RFN6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000428032};+++[E5RFP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000430341};+++[H0YBL8_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000429795}; Flags: Fragment;+++[K7EMH5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000466506}; Flags: Fragment;+++[K7ERP5_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 10 {ECO:0000313|Ensembl:ENSP00000468351}; Flags: Fragment;"]
[10350,"'ABCA9'",10.95,7,8.975,"02010///ABC transporters",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0042626///ATPase activity, coupled to transmembrane movement of substances+++GO:0016887///ATPase activity+++GO:0005319///lipid transporter activity","GO:0055085///transmembrane transport+++GO:0006869///lipid transport","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003593///AAA+ ATPase domain+++IPR026082///ABC transporter A+++IPR003439///ABC transporter-like","[ABCA9_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family A member 9;+++[H0Y4U7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000394264};+++[K7EJJ0_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family A member 9 {ECO:0000313|Ensembl:ENSP00000465191}; Flags: Fragment;"]
[10352,"'WARS2'",131,86,108.5,"00970///Aminoacyl-tRNA biosynthesis",null,"M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03664///L-Tryptophan -tRNA(Trp) ligase (AMP-forming)   ATP + L-Tryptophan + tRNA(Trp) <=> AMP + Diphosphate + L-Tryptophanyl-tRNA(Trp)","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000166///nucleotide binding+++GO:0004830///tryptophan-tRNA ligase activity+++GO:0016874///ligase activity+++GO:0005524///ATP binding","GO:0006436///tryptophanyl-tRNA aminoacylation+++GO:0001570///vasculogenesis+++GO:0006412///translation+++GO:0070183///mitochondrial tryptophanyl-tRNA aminoacylation+++GO:0006418///tRNA aminoacylation for protein translation","IPR001412///Aminoacyl-tRNA synthetase, class I, conserved site+++IPR002305///Aminoacyl-tRNA synthetase, class Ic+++IPR002306///Tryptophan-tRNA ligase+++IPR024109///Tryptophan-tRNA ligase, bacterial-type+++IPR014729///Rossmann-like alpha/beta/alpha sandwich fold","[SYWM_HUMAN|Reviewed]RecName: Full=Tryptophan--tRNA ligase, mitochondrial; EC=6.1.1.2; AltName: Full=(Mt)TrpRS; AltName: Full=Tryptophanyl-tRNA synthetase; Short=TrpRS; Flags: Precursor;+++[B7Z448_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51886, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH12434.1};+++[B7Z6G7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53098, highly similar to Tryptophanyl-tRNA synthetase, mitochondrial {ECO:0000313|EMBL:BAH13253.1};"]
[1036,"'CDO1'",50,61,55.5,"00270///Cysteine and methionine metabolism+++01100///Metabolic pathways+++00430///Taurine and hypotaurine metabolism",null,null,"R00893///L-Cysteine:oxygen oxidoreductase   L-Cysteine + Oxygen <=> 3-Sulfino-L-alanine","GO:0005829///cytosol","GO:0005506///iron ion binding+++GO:0017172///cysteine dioxygenase activity+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0051213///dioxygenase activity+++GO:0008198///ferrous iron binding+++GO:0016702///oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen","GO:0010243///response to organonitrogen compound+++GO:0045471///response to ethanol+++GO:0051384///response to glucocorticoid+++GO:0019448///L-cysteine catabolic process+++GO:0043200///response to amino acid+++GO:0007595///lactation+++GO:0055114///oxidation-reduction process+++GO:0051591///response to cAMP+++GO:0000097///sulfur amino acid biosynthetic process+++GO:0006954///inflammatory response+++GO:0006534///cysteine metabolic process+++GO:0042412///taurine biosynthetic process+++GO:0033762///response to glucagon","IPR010300///Cysteine dioxygenase type I+++IPR014710///RmlC-like jelly roll fold+++IPR011051///RmlC-like cupin domain superfamily","[CDO1_HUMAN|Reviewed]RecName: Full=Cysteine dioxygenase type 1; EC=1.13.11.20; AltName: Full=Cysteine dioxygenase type I; Short=CDO; Short=CDO-I;"]
[10360,"'NPM3'",200,142,171,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0009897///external side of plasma membrane+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm","GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0038023///signaling receptor activity","GO:0009303///rRNA transcription+++GO:0070267///oncosis+++GO:0006338///chromatin remodeling+++GO:0006364///rRNA processing","IPR036824///Nucleoplasmin core domain superfamily+++IPR024057///Nucleoplasmin core domain+++IPR004301///Nucleoplasmin family","[NPM3_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-3;"]
[10361,"'NPM2'",4,2,3,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0000789///cytoplasmic chromatin+++GO:0000790///nuclear chromatin+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0042393///histone binding","GO:0007338///single fertilization+++GO:0009994///oocyte differentiation+++GO:0006325///chromatin organization+++GO:0051260///protein homooligomerization+++GO:0045740///positive regulation of DNA replication+++GO:0043085///positive regulation of catalytic activity+++GO:0001824///blastocyst development+++GO:0006338///chromatin remodeling+++GO:0045836///positive regulation of meiotic nuclear division+++GO:0051054///positive regulation of DNA metabolic process+++GO:0007275///multicellular organism development+++GO:0007096///regulation of exit from mitosis","IPR036824///Nucleoplasmin core domain superfamily+++IPR024057///Nucleoplasmin core domain+++IPR004301///Nucleoplasmin family","[NPM2_HUMAN|Reviewed]RecName: Full=Nucleoplasmin-2;+++[E5RFQ8_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000428016}; Flags: Fragment;+++[E5RGN1_HUMAN|Unreviewed]SubName: Full=Nucleoplasmin-2 {ECO:0000313|Ensembl:ENSP00000429984}; Flags: Fragment;"]
[10362,"'HMG20B'",1727,1439,1583,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016604///nuclear body+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004407///histone deacetylase activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0035914///skeletal muscle cell differentiation+++GO:0016575///histone deacetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0007049///cell cycle+++GO:0007596///blood coagulation+++GO:0033234///negative regulation of protein sumoylation+++GO:0045666///positive regulation of neuron differentiation","IPR036910///High mobility group box domain superfamily+++IPR009071///High mobility group box domain","[HM20B_HUMAN|Reviewed]RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; Short=SMARCE1-related protein; AltName: Full=BRCA2-associated factor 35; AltName: Full=HMG box-containing protein 20B; AltName: Full=HMG domain-containing protein 2; AltName: Full=HMG domain-containing protein HMGX2; AltName: Full=Sox-like transcriptional factor; AltName: Full=Structural DNA-binding protein BRAF35;+++[A4IF61_HUMAN|Unreviewed]SubName: Full=HMG20B protein {ECO:0000313|EMBL:AAI34414.1}; Flags: Fragment;+++[B5MDG7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000262949}; Flags: Fragment;+++[C9J8X5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000410924}; Flags: Fragment;+++[C9JQA7_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000402877}; Flags: Fragment;+++[C9K049_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393904}; Flags: Fragment;+++[F8WES5_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000393481};+++[K7EJR8_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related {ECO:0000313|Ensembl:ENSP00000465293}; Flags: Fragment;+++[Q8WYT5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein pp8857 {ECO:0000313|EMBL:AAL55873.1};"]
[10363,"'HMG20A'",396,481,438.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding","GO:0033234///negative regulation of protein sumoylation+++GO:0045665///negative regulation of neuron differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006325///chromatin organization","IPR036910///High mobility group box domain superfamily+++IPR009071///High mobility group box domain","[HM20A_HUMAN|Reviewed]RecName: Full=High mobility group protein 20A; AltName: Full=HMG box-containing protein 20A; AltName: Full=HMG domain-containing protein 1; AltName: Full=HMG domain-containing protein HMGX1;+++[B4DMG1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57155, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAG59873.1}; SubName: Full=cDNA, FLJ79180, highly similar to High mobility group protein 20A {ECO:0000313|EMBL:BAH14652.1};+++[H0YK55_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452665}; Flags: Fragment;+++[H0YKL0_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452847}; Flags: Fragment;+++[H0YKM5_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000452864}; Flags: Fragment;+++[H0YM80_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453498}; Flags: Fragment;+++[H0YMG2_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453592};+++[H0YMS9_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000453727}; Flags: Fragment;+++[H0YNS8_HUMAN|Unreviewed]SubName: Full=High mobility group protein 20A {ECO:0000313|Ensembl:ENSP00000454136}; Flags: Fragment;"]
[10365,"'KLF2'",204,147,175.5,"05418///Fluid shear stress and atherosclerosis+++04371///Apelin signaling pathway+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0001701///in utero embryonic development+++GO:0070301///cellular response to hydrogen peroxide+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:0043249///erythrocyte maturation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060509///type I pneumocyte differentiation+++GO:0071498///cellular response to fluid shear stress+++GO:0035264///multicellular organism growth+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071409///cellular response to cycloheximide+++GO:0032715///negative regulation of interleukin-6 production+++GO:0000902///cell morphogenesis+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0034616///response to laminar fluid shear stress+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0040029///regulation of gene expression, epigenetic+++GO:1901653///cellular response to peptide+++GO:0071347///cellular response to interleukin-1+++GO:0051247///positive regulation of protein metabolic process+++GO:0034101///erythrocyte homeostasis+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0097533///cellular stress response to acid chemical+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0071356///cellular response to tumor necrosis factor+++GO:0071407///cellular response to organic cyclic compound+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[KLF2_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 2; AltName: Full=Lung krueppel-like factor;+++[K7EJ60_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 2 {ECO:0000313|Ensembl:ENSP00000465035};"]
[10367,"'MICU1'",1045,1069,1057,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0032592///integral component of mitochondrial membrane+++GO:0034704///calcium channel complex+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005622///intracellular+++GO:1990246///uniplex complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0042802///identical protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity","GO:0070509///calcium ion import+++GO:0051560///mitochondrial calcium ion homeostasis+++GO:0051260///protein homooligomerization+++GO:0006952///defense response+++GO:0036444///calcium import into the mitochondrion+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0051561///positive regulation of mitochondrial calcium ion concentration+++GO:0006851///mitochondrial calcium ion transmembrane transport","IPR018247///EF-Hand 1, calcium-binding site+++IPR002048///EF-hand domain+++IPR011992///EF-hand domain pair+++IPR039800///Calcium uptake protein 1/2/3","[MICU1_HUMAN|Reviewed]RecName: Full=Calcium uptake protein 1, mitochondrial; AltName: Full=Atopy-related autoantigen CALC {ECO:0000303|PubMed:16002733}; Short=ara CALC {ECO:0000303|PubMed:16002733}; AltName: Full=Calcium-binding atopy-related autoantigen 1 {ECO:0000303|PubMed:16002733}; AltName: Allergen=Hom s 4 {ECO:0000303|PubMed:16002733}; Flags: Precursor;+++[A0A0U1RRK1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000489563};+++[A0A286YF11_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000493232};+++[E9PQV6_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000432492}; Flags: Fragment;+++[F6XEV2_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000381745};+++[S4R3D7_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474192}; Flags: Fragment;+++[S4R3V1_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474775}; Flags: Fragment;+++[S4R3W3_HUMAN|Unreviewed]SubName: Full=Calcium uptake protein 1, mitochondrial {ECO:0000313|Ensembl:ENSP00000474809}; Flags: Fragment;"]
[10369,"'CACNG2'",5,0,2.5,"04260///Cardiac muscle contraction+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04921///Oxytocin signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04010///MAPK signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++05410///Hypertrophic cardiomyopathy (HCM)","H00773///Autosomal dominant mental retardation",null,null,"GO:0045202///synapse+++GO:0044300///cerebellar mossy fiber+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0032281///AMPA glutamate receptor complex+++GO:0016020///membrane+++GO:0030666///endocytic vesicle membrane+++GO:0098978///glutamatergic synapse+++GO:0030054///cell junction+++GO:0005829///cytosol+++GO:0036477///somatodendritic compartment+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099061///integral component of postsynaptic density membrane+++GO:0043005///neuron projection+++GO:0005891///voltage-gated calcium channel complex+++GO:0014069///postsynaptic density+++GO:0016021///integral component of membrane+++GO:0098839///postsynaptic density membrane","GO:0005244///voltage-gated ion channel activity+++GO:0035255///ionotropic glutamate receptor binding+++GO:0016247///channel regulator activity+++GO:0005515///protein binding+++GO:0005262///calcium channel activity+++GO:0005245///voltage-gated calcium channel activity","GO:2000969///positive regulation of AMPA receptor activity+++GO:0099590///neurotransmitter receptor internalization+++GO:0006816///calcium ion transport+++GO:0098970///postsynaptic neurotransmitter receptor diffusion trapping+++GO:0034765///regulation of ion transmembrane transport+++GO:0051592///response to calcium ion+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:1904510///positive regulation of protein localization to basolateral plasma membrane+++GO:0007528///neuromuscular junction development+++GO:2000311///regulation of AMPA receptor activity+++GO:0050877///nervous system process+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0019226///transmission of nerve impulse+++GO:0098943///neurotransmitter receptor transport, postsynaptic endosome to lysosome+++GO:0060081///membrane hyperpolarization+++GO:0006612///protein targeting to membrane+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0060082///eye blink reflex+++GO:0042391///regulation of membrane potential+++GO:0006811///ion transport+++GO:0070588///calcium ion transmembrane transport+++GO:0051899///membrane depolarization","IPR004031///PMP-22/EMP/MP20/Claudin superfamily+++IPR005422///Voltage-dependent calcium channel, gamma-2 subunit+++IPR008368///Voltage-dependent calcium channel, gamma subunit","[CCG2_HUMAN|Reviewed]RecName: Full=Voltage-dependent calcium channel gamma-2 subunit; AltName: Full=Neuronal voltage-gated calcium channel gamma-2 subunit; AltName: Full=Transmembrane AMPAR regulatory protein gamma-2; Short=TARP gamma-2;"]
[10370,"'CITED2'",5506,4697,5101.5,"04137///Mitophagy - animal","H01926///Ventricular septal defect (VSD)+++H00546///Atrial septal defect",null,null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin","GO:0046332///SMAD binding+++GO:0050693///LBD domain binding+++GO:0003713///transcription coactivator activity+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding+++GO:0035035///histone acetyltransferase binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding","GO:0007417///central nervous system development+++GO:0070986///left/right axis specification+++GO:0060411///cardiac septum morphogenesis+++GO:0009612///response to mechanical stimulus+++GO:0022409///positive regulation of cell-cell adhesion+++GO:0034405///response to fluid shear stress+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030851///granulocyte differentiation+++GO:0003197///endocardial cushion development+++GO:0007507///heart development+++GO:0008584///male gonad development+++GO:0061308///cardiac neural crest cell development involved in heart development+++GO:0043066///negative regulation of apoptotic process+++GO:2000020///positive regulation of male gonad development+++GO:0060349///bone morphogenesis+++GO:0021602///cranial nerve morphogenesis+++GO:0048821///erythrocyte development+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0048538///thymus development+++GO:0007530///sex determination+++GO:0060971///embryonic heart tube left/right pattern formation+++GO:0001947///heart looping+++GO:0045787///positive regulation of cell cycle+++GO:0035914///skeletal muscle cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0030154///cell differentiation+++GO:0061371///determination of heart left/right asymmetry+++GO:0001944///vasculature development+++GO:0001889///liver development+++GO:0001701///in utero embryonic development+++GO:0007422///peripheral nervous system development+++GO:0001829///trophectodermal cell differentiation+++GO:0008283///cell proliferation+++GO:0001570///vasculogenesis+++GO:0001568///blood vessel development+++GO:0001841///neural tube formation+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0030325///adrenal gland development+++GO:0003156///regulation of animal organ formation+++GO:0035802///adrenal cortex formation+++GO:0003151///outflow tract morphogenesis+++GO:0043627///response to estrogen+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0061428///negative regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:1900164///nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:0035360///positive regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0010629///negative regulation of gene expression+++GO:0071363///cellular response to growth factor stimulus+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0007275///multicellular organism development+++GO:0030336///negative regulation of cell migration+++GO:0007368///determination of left/right symmetry+++GO:0060412///ventricular septum morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001666///response to hypoxia+++GO:0048536///spleen development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002521///leukocyte differentiation+++GO:0001843///neural tube closure+++GO:0007569///cell aging+++GO:0001892///embryonic placenta development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0003281///ventricular septum development+++GO:0061156///pulmonary artery morphogenesis+++GO:0046697///decidualization+++GO:0060136///embryonic process involved in female pregnancy","IPR007576///CITED","[CITE2_HUMAN|Reviewed]RecName: Full=Cbp/p300-interacting transactivator 2; AltName: Full=MSG-related protein 1; Short=MRG-1; AltName: Full=P35srj;+++[A0A0A0MTM3_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator 2 {ECO:0000313|Ensembl:ENSP00000444198};+++[D9ZGF1_HUMAN|Unreviewed]SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 {ECO:0000313|EMBL:ADL14510.1}; SubName: Full=Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, isoform CRA_d {ECO:0000313|EMBL:EAW47894.1};"]
[10371,"'SEMA3A'",274,306,290,"04360///Axon guidance","H00556///CHARGE syndrome+++H00255///Hypogonadotropic hypogonadism","M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin","GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0030424///axon+++GO:0005887///integral component of plasma membrane+++GO:0030425///dendrite","GO:0045499///chemorepellent activity+++GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding","GO:0002027///regulation of heart rate+++GO:0001764///neuron migration+++GO:0021637///trigeminal nerve structural organization+++GO:0050919///negative chemotaxis+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:0021675///nerve development+++GO:0006915///apoptotic process+++GO:0048846///axon extension involved in axon guidance+++GO:0007411///axon guidance+++GO:0048813///dendrite morphogenesis+++GO:0030517///negative regulation of axon extension+++GO:0021785///branchiomotor neuron axon guidance+++GO:0060385///axonogenesis involved in innervation+++GO:0007413///axonal fasciculation+++GO:0048841///regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:1903045///neural crest cell migration involved in sympathetic nervous system development+++GO:0061549///sympathetic ganglion development+++GO:0001755///neural crest cell migration+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:0061551///trigeminal ganglion development+++GO:0046330///positive regulation of JNK cascade+++GO:0021612///facial nerve structural organization+++GO:2001224///positive regulation of neuron migration+++GO:0021772///olfactory bulb development+++GO:0030335///positive regulation of cell migration+++GO:0097490///sympathetic neuron projection extension+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0150020///basal dendrite arborization+++GO:0010633///negative regulation of epithelial cell migration+++GO:0048880///sensory system development+++GO:0010977///negative regulation of neuron projection development+++GO:0008045///motor neuron axon guidance+++GO:0007275///multicellular organism development+++GO:1902287///semaphorin-plexin signaling pathway involved in axon guidance+++GO:2000020///positive regulation of male gonad development+++GO:0097491///sympathetic neuron projection guidance+++GO:1903375///facioacoustic ganglion development+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0030154///cell differentiation+++GO:0036486///ventral trunk neural crest cell migration+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0048485///sympathetic nervous system development","IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR027231///Semaphorin+++IPR003599///Immunoglobulin subtype+++IPR013151///Immunoglobulin+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR036352///Sema domain superfamily+++IPR016201///PSI domain+++IPR007110///Immunoglobulin-like domain+++IPR001627///Sema domain","[SEM3A_HUMAN|Reviewed]RecName: Full=Semaphorin-3A; AltName: Full=Semaphorin III; Short=Sema III; Flags: Precursor;+++[A0A0C4DG50_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000402093}; Flags: Fragment;+++[C9J9C4_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000391900}; Flags: Fragment;+++[C9JD25_HUMAN|Unreviewed]SubName: Full=Semaphorin-3A {ECO:0000313|Ensembl:ENSP00000404800}; Flags: Fragment;+++[Q75MQ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAS02028.1}; Flags: Fragment;+++[Q86UJ2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3A {ECO:0000313|EMBL:AAP22350.1}; Flags: Fragment;"]
[10376,"'TUBA1B'",12410.66,10155.69,11283.175,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection+++04530///Tight junction+++04210///Apoptosis","H00058///Amyotrophic lateral sclerosis (ALS)+++H00268///Lissencephaly (LIS)+++H00271///Polymicrogyria",null,null,"GO:0005874///microtubule+++GO:0045121///membrane raft+++GO:0015630///microtubule cytoskeleton+++GO:0005881///cytoplasmic microtubule+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath","GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0000166///nucleotide binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007017///microtubule-based process+++GO:0000278///mitotic cell cycle+++GO:0071353///cellular response to interleukin-4+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0000226///microtubule cytoskeleton organization+++GO:0007010///cytoskeleton organization+++GO:0051301///cell division","IPR000217///Tubulin+++IPR036525///Tubulin/FtsZ, GTPase domain superfamily+++IPR037103///Tubulin/FtsZ, C-terminal domain superfamily+++IPR023123///Tubulin, C-terminal+++IPR002452///Alpha tubulin+++IPR017975///Tubulin, conserved site+++IPR018316///Tubulin/FtsZ, 2-layer sandwich domain+++IPR008280///Tubulin/FtsZ, C-terminal+++IPR003008///Tubulin/FtsZ, GTPase domain","[TBA1B_HUMAN|Reviewed]RecName: Full=Tubulin alpha-1B chain; AltName: Full=Alpha-tubulin ubiquitous; AltName: Full=Tubulin K-alpha-1; AltName: Full=Tubulin alpha-ubiquitous chain; Contains: RecName: Full=Detyrosinated tubulin alpha-1B chain;+++[F8VRK0_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448648}; Flags: Fragment;+++[F8VU66_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000448045};+++[F8VVB9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449325}; Flags: Fragment;+++[F8VWV9_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449460}; Flags: Fragment;+++[F8VX09_HUMAN|Unreviewed]SubName: Full=Tubulin alpha-1B chain {ECO:0000313|Ensembl:ENSP00000449748}; Flags: Fragment;"]
[10379,"'IRF9'",1679,1539,1609,"05164///Influenza A+++04630///Jak-STAT signaling pathway+++05160///Hepatitis C+++05162///Measles+++05165///Human papillomavirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05168///Herpes simplex infection+++04621///NOD-like receptor signaling pathway+++04625///C-type lectin receptor signaling pathway+++04217///Necroptosis+++04380///Osteoclast differentiation+++05203///Viral carcinogenesis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity","GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051607///defense response to virus+++GO:0007166///cell surface receptor signaling pathway+++GO:0060337///type I interferon signaling pathway","IPR017855///SMAD-like domain superfamily+++IPR019817///Interferon regulatory factor, conserved site+++IPR001346///Interferon regulatory factor DNA-binding domain+++IPR019471///Interferon regulatory factor-3+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR008984///SMAD/FHA domain superfamily","[IRF9_HUMAN|Reviewed]RecName: Full=Interferon regulatory factor 9; Short=IRF-9; AltName: Full=IFN-alpha-responsive transcription factor subunit; AltName: Full=ISGF3 p48 subunit; AltName: Full=Interferon-stimulated gene factor 3 gamma; Short=ISGF-3 gamma; AltName: Full=Transcriptional regulator ISGF3 subunit gamma;+++[H0YMB0_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453534};+++[H0YMB6_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000453540}; Flags: Fragment;+++[H0YNM9_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454078};+++[H0YNP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000454095}; Flags: Fragment;+++[H7BXP4_HUMAN|Unreviewed]SubName: Full=Interferon regulatory factor 9 {ECO:0000313|Ensembl:ENSP00000313529}; Flags: Fragment;"]
[10380,"'BPNT1'",345,331,338,"01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++00920///Sulfur metabolism+++01130///Biosynthesis of antibiotics",null,null,"R00508///3'-phospho-5'-adenylyl sulfate 3'-phosphohydrolase   3'-Phosphoadenylyl sulfate + H2O <=> Adenylyl sulfate + Orthophosphate+++R00188///adenosine-3',5'-bisphosphate 3'-phosphohydrolase   Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate","GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005615///extracellular space","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008441///3'(2'),5'-bisphosphate nucleotidase activity+++GO:0016787///hydrolase activity+++GO:0019864///IgG binding+++GO:0004190///aspartic-type endopeptidase activity+++GO:0046983///protein dimerization activity+++GO:0003779///actin binding","GO:0070233///negative regulation of T cell apoptotic process+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0010628///positive regulation of gene expression+++GO:0055085///transmembrane transport+++GO:0001895///retina homeostasis+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0007399///nervous system development+++GO:0016311///dephosphorylation+++GO:0006508///proteolysis+++GO:0046854///phosphatidylinositol phosphorylation","IPR020550///Inositol monophosphatase, conserved site+++IPR020583///Inositol monophosphatase, metal-binding site+++IPR000760///Inositol monophosphatase-like","[BPNT1_HUMAN|Reviewed]RecName: Full=3'(2'),5'-bisphosphate nucleotidase 1; EC=3.1.3.7; AltName: Full=Bisphosphate 3'-nucleotidase 1; AltName: Full=PAP-inositol 1,4-phosphatase; Short=PIP;+++[A6NF51_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000346862};+++[B7Z9J7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78861, highly similar to 3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|EMBL:BAH14333.1};+++[F8VRY7_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000448740}; Flags: Fragment;+++[F8VVW8_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000449883}; Flags: Fragment;+++[F8VZG4_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446850}; Flags: Fragment;+++[F8W1J0_HUMAN|Unreviewed]SubName: Full=3'(2'),5'-bisphosphate nucleotidase 1 {ECO:0000313|Ensembl:ENSP00000446953}; Flags: Fragment;+++[V9HWF9_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 20 {ECO:0000313|EMBL:ACJ13648.1}; SubName: Full=Testicular tissue protein Li 29 {ECO:0000313|EMBL:AEE60942.1};"]
[10381,"'TUBB3'",9061.77,5998.61,7530.19,"04540///Gap junction+++05130///Pathogenic Escherichia coli infection+++04145///Phagosome","H01579///Congenital symmetric circumferential skin creases+++H01740///Macrothrombocytopenia+++H00679///Hypomyelinating leukodystrophy+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect+++H00271///Polymicrogyria+++H01881///Complex cortical dysplasia with other brain malformations",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0030425///dendrite+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0030424///axon","GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005515///protein binding+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007017///microtubule-based process+++GO:0007411///axon guidance+++GO:0000278///mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0030182///neuron differentiation+++GO:0007010///cytoskeleton organization","IPR002453///Beta tubulin+++IPR003008///Tubulin/FtsZ, GTPase domain+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR008280///Tubulin/FtsZ, C-terminal+++IPR000217///Tubulin+++IPR013838///Beta tubulin, autoregulation binding site+++IPR017975///Tubulin, conserved site+++IPR018316///Tubulin/FtsZ, 2-layer sandwich domain+++IPR023123///Tubulin, C-terminal+++IPR036525///Tubulin/FtsZ, GTPase domain superfamily+++IPR037103///Tubulin/FtsZ, C-terminal domain superfamily+++IPR017452///GPCR, rhodopsin-like, 7TM","[TBB3_HUMAN|Reviewed]RecName: Full=Tubulin beta-3 chain; AltName: Full=Tubulin beta-4 chain; AltName: Full=Tubulin beta-III;+++[G3V2A3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[G3V2N6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_d {ECO:0000313|EMBL:EAW66672.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450765};+++[G3V2R8_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_e {ECO:0000313|EMBL:EAW66673.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000450822};+++[G3V3J6_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_b {ECO:0000313|EMBL:EAW66670.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451276};+++[G3V3R4_HUMAN|Unreviewed]SubName: Full=HCG1983504, isoform CRA_c {ECO:0000313|EMBL:EAW66671.1}; SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451378};+++[G3V3W7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451465};+++[G3V4U2_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000451985};+++[G3V542_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452166}; Flags: Fragment;+++[G3V5W4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-3 chain {ECO:0000313|Ensembl:ENSP00000452554};+++[Q3ZCR3_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q53G92_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[Q9BV28_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;"]
[10382,"'TUBB4A'",3528,2782,3155,"05130///Pathogenic Escherichia coli infection+++04540///Gap junction+++04145///Phagosome","H00679///Hypomyelinating leukodystrophy+++H01740///Macrothrombocytopenia+++H01881///Complex cortical dysplasia with other brain malformations+++H01897///Oocyte maturation defect+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01579///Congenital symmetric circumferential skin creases+++H00271///Polymicrogyria",null,null,"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005929///cilium+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0033269///internode region of axon+++GO:0042995///cell projection+++GO:0005930///axoneme+++GO:0005737///cytoplasm+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0005200///structural constituent of cytoskeleton+++GO:0005509///calcium ion binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000226///microtubule cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007010///cytoskeleton organization+++GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0031115///negative regulation of microtubule polymerization","IPR037103///Tubulin/FtsZ, C-terminal domain superfamily+++IPR013838///Beta tubulin, autoregulation binding site+++IPR002453///Beta tubulin+++IPR008280///Tubulin/FtsZ, C-terminal+++IPR018316///Tubulin/FtsZ, 2-layer sandwich domain+++IPR036525///Tubulin/FtsZ, GTPase domain superfamily+++IPR023123///Tubulin, C-terminal+++IPR003008///Tubulin/FtsZ, GTPase domain+++IPR017975///Tubulin, conserved site+++IPR000217///Tubulin","[TBB4A_HUMAN|Reviewed]RecName: Full=Tubulin beta-4A chain; AltName: Full=Tubulin 5 beta; AltName: Full=Tubulin beta-4 chain;+++[M0QX14_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000468843};+++[M0QY37_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469560};+++[M0QY85_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469660}; Flags: Fragment;+++[M0QYM7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000469936}; Flags: Fragment;+++[M0QZL7_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000470627}; Flags: Fragment;+++[M0R042_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R0M1_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471320};+++[M0R0X0_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000471503};+++[M0R1I1_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352}; Flags: Fragment;+++[M0R278_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472375}; Flags: Fragment;+++[M0R2D3_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472481}; Flags: Fragment;+++[M0R2T4_HUMAN|Unreviewed]SubName: Full=Tubulin beta-4A chain {ECO:0000313|Ensembl:ENSP00000472795};"]
[10383,"'TUBB4B'",6033.03,4244.54,5138.785,"04540///Gap junction+++04145///Phagosome+++05130///Pathogenic Escherichia coli infection","H01579///Congenital symmetric circumferential skin creases+++H00679///Hypomyelinating leukodystrophy+++H01881///Complex cortical dysplasia with other brain malformations+++H01740///Macrothrombocytopenia+++H00271///Polymicrogyria+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)+++H01897///Oocyte maturation defect",null,null,"GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:1903561///extracellular vesicle+++GO:0035578///azurophil granule lumen+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005576///extracellular region","GO:0005200///structural constituent of cytoskeleton+++GO:0003924///GTPase activity+++GO:0003725///double-stranded RNA binding+++GO:0042288///MHC class I protein binding+++GO:0005525///GTP binding+++GO:0051082///unfolded protein binding+++GO:0000166///nucleotide binding","GO:0000278///mitotic cell cycle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007010///cytoskeleton organization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0042267///natural killer cell mediated cytotoxicity+++GO:0043312///neutrophil degranulation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0007017///microtubule-based process+++GO:0000226///microtubule cytoskeleton organization","IPR000217///Tubulin+++IPR037103///Tubulin/FtsZ, C-terminal domain superfamily+++IPR036525///Tubulin/FtsZ, GTPase domain superfamily+++IPR017975///Tubulin, conserved site+++IPR008280///Tubulin/FtsZ, C-terminal+++IPR002967///Delta tubulin+++IPR013838///Beta tubulin, autoregulation binding site+++IPR023123///Tubulin, C-terminal+++IPR003008///Tubulin/FtsZ, GTPase domain+++IPR002453///Beta tubulin+++IPR018316///Tubulin/FtsZ, 2-layer sandwich domain","[TBB4B_HUMAN|Reviewed]RecName: Full=Tubulin beta-4B chain; AltName: Full=Tubulin beta-2 chain; AltName: Full=Tubulin beta-2C chain;+++[Q8IZ29_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q8N6N5_HUMAN|Unreviewed]RecName: Full=Tubulin beta chain {ECO:0000256|RuleBase:RU000352};+++[Q96HX0_HUMAN|Unreviewed]SubName: Full=TUBB2C protein {ECO:0000313|EMBL:AAH08006.1}; Flags: Fragment;"]
[10384,"'BTN3A3'",93.5,86.64,90.07,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0005102///signaling receptor binding","GO:0050852///T cell receptor signaling pathway+++GO:0050776///regulation of immune response+++GO:0002376///immune system process+++GO:0006366///transcription by RNA polymerase II+++GO:0002250///adaptive immune response+++GO:0015031///protein transport+++GO:0002456///T cell mediated immunity+++GO:0001701///in utero embryonic development","IPR003879///Butyrophylin-like, SPRY domain+++IPR013106///Immunoglobulin V-set domain+++IPR003599///Immunoglobulin subtype+++IPR001870///B30.2/SPRY domain+++IPR006574///SPRY-associated+++IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR037954///Butyrophilin subfamily 3, PRY/SPRY domain+++IPR007110///Immunoglobulin-like domain+++IPR003877///SPRY domain","[BT3A3_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 3 member A3; Flags: Precursor;+++[A0A024R042_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 3, member A3, isoform CRA_b {ECO:0000313|EMBL:EAW55574.1};+++[A0A089GIA6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 secreted isoform {ECO:0000313|EMBL:AIP98384.1};+++[C9J3Q8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417234}; Flags: Fragment;+++[C9J877_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000417717}; Flags: Fragment;+++[C9JNZ3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420339}; Flags: Fragment;+++[C9JQT8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000420147}; Flags: Fragment;+++[C9JUV8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419445}; Flags: Fragment;+++[C9JVU4_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419312}; Flags: Fragment;+++[C9JZT5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 3 member A3 {ECO:0000313|Ensembl:ENSP00000419736}; Flags: Fragment;+++[D6RDG3_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;+++[H0Y9Y1_HUMAN|Unreviewed]RecName: Full=Transcription factor BTF3 {ECO:0000256|RuleBase:RU361272}; Flags: Fragment;"]
[10385,"'BTN2A2'",233,181,207,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0050852///T cell receptor signaling pathway+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0045591///positive regulation of regulatory T cell differentiation+++GO:0050776///regulation of immune response+++GO:0031324///negative regulation of cellular metabolic process+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0050710///negative regulation of cytokine secretion","IPR001870///B30.2/SPRY domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR003879///Butyrophylin-like, SPRY domain+++IPR003877///SPRY domain+++IPR013106///Immunoglobulin V-set domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR006574///SPRY-associated+++IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold+++IPR037958///Butyrophilin subfamily 1/2, SPRY/PRY domain","[BT2A2_HUMAN|Reviewed]RecName: Full=Butyrophilin subfamily 2 member A2; Flags: Precursor;+++[A0A024R038_HUMAN|Unreviewed]SubName: Full=Butyrophilin, subfamily 2, member A2, isoform CRA_a {ECO:0000313|EMBL:EAW55564.1};+++[C9IY66_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418857}; Flags: Fragment;+++[C9IZY2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418965}; Flags: Fragment;+++[C9J8J5_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418176}; Flags: Fragment;+++[C9J8R3_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417676}; Flags: Fragment;+++[C9JAJ6_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417511}; Flags: Fragment;+++[C9JWH2_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000419226}; Flags: Fragment;+++[F8WC65_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000418657};+++[H7C4E8_HUMAN|Unreviewed]SubName: Full=Butyrophilin subfamily 2 member A2 {ECO:0000313|Ensembl:ENSP00000417129}; Flags: Fragment;"]
[10388,"'SYCP2'",12,17,14.5,{"$nulls":4},"GO:0005782///peroxisomal matrix+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000800///lateral element+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005777///peroxisome+++GO:0000795///synaptonemal complex+++GO:0005694///chromosome+++GO:0032991///protein-containing complex","GO:0033814///propanoyl-CoA C-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0008526///phosphatidylinositol transporter activity+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0005102///signaling receptor binding+++GO:0050632///propionyl-CoA C2-trimethyltridecanoyltransferase activity+++GO:0000062///fatty-acyl-CoA binding+++GO:0003824///catalytic activity+++GO:0008289///lipid binding+++GO:0046982///protein heterodimerization activity+++GO:0070538///oleic acid binding","GO:0006701///progesterone biosynthetic process+++GO:1901373///lipid hydroperoxide transport+++GO:0072659///protein localization to plasma membrane+++GO:0007049///cell cycle+++GO:0043066///negative regulation of apoptotic process+++GO:0007140///male meiotic nuclear division+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0045940///positive regulation of steroid metabolic process+++GO:0007143///female meiotic nuclear division+++GO:0036109///alpha-linolenic acid metabolic process+++GO:0009566///fertilization+++GO:0006699///bile acid biosynthetic process+++GO:0032385///positive regulation of intracellular cholesterol transport+++GO:0006869///lipid transport+++GO:0007031///peroxisome organization+++GO:0015914///phospholipid transport+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0051301///cell division+++GO:0006694///steroid biosynthetic process+++GO:0009887///animal organ morphogenesis+++GO:0048808///male genitalia morphogenesis+++GO:0051321///meiotic cell cycle+++GO:0007130///synaptonemal complex assembly+++GO:0006625///protein targeting to peroxisome","IPR024835///Synaptonemal complex protein 1/2+++IPR024832///Synaptonemal complex protein 2","[SYCP2_HUMAN|Reviewed]RecName: Full=Synaptonemal complex protein 2; Short=SCP-2; AltName: Full=Synaptonemal complex lateral element protein; Short=hsSCP2;+++[A2A2M9_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000399300}; Flags: Fragment;+++[A2A340_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000404358}; Flags: Fragment;+++[A2A341_HUMAN|Unreviewed]SubName: Full=Synaptonemal complex protein 2 {ECO:0000313|Ensembl:ENSP00000402456}; Flags: Fragment;+++[A6QL60_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAI46799.1}; Flags: Fragment;+++[H0YCB0_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000431279}; Flags: Fragment;+++[H0YD06_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000432645}; Flags: Fragment;+++[H0YEU8_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000436581}; Flags: Fragment;+++[H0YF61_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000437317}; Flags: Fragment;+++[L0R5C7_HUMAN|Unreviewed]SubName: Full=Alternative protein SCP2 {ECO:0000313|EMBL:CCO13809.1};+++[Q8IWA1_HUMAN|Unreviewed]SubName: Full=SYCP2 protein {ECO:0000313|EMBL:AAH40566.1}; Flags: Fragment;"]
[10389,"'SCML2'",5,2,3.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0031519///PcG protein complex","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0009653///anatomical structure morphogenesis","IPR004092///Mbt repeat+++IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR038348///SLED domain superfamily+++IPR021987///SLED domain+++IPR001660///Sterile alpha motif domain+++IPR033763///Polycomb group protein, RNA binding region","[SCML2_HUMAN|Reviewed]RecName: Full=Sex comb on midleg-like protein 2;+++[H0Y6S1_HUMAN|Unreviewed]SubName: Full=Sex comb on midleg-like protein 2 {ECO:0000313|Ensembl:ENSP00000407315}; Flags: Fragment;"]
[1039,"'CDR2'",574,504,539,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","IPR026079///Cerebellar degeneration-related protein 2","[CDR2_HUMAN|Reviewed]RecName: Full=Cerebellar degeneration-related protein 2; AltName: Full=Major Yo paraneoplastic antigen; AltName: Full=Paraneoplastic cerebellar degeneration-associated antigen;+++[H3BN65_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000454706}; Flags: Fragment;+++[H3BQS4_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000455915};+++[H3BTR1_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457289}; Flags: Fragment;+++[H3BU23_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457432}; Flags: Fragment;+++[H3BUE0_HUMAN|Unreviewed]SubName: Full=Cerebellar degeneration-related protein 2 {ECO:0000313|Ensembl:ENSP00000457596}; Flags: Fragment;"]
[10390,"'CEPT1'",113,80,96.5,"01100///Metabolic pathways+++00564///Glycerophospholipid metabolism+++00440///Phosphonate and phosphinate metabolism+++00565///Ether lipid metabolism+++01110///Biosynthesis of secondary metabolites","H00481///Cone-rod dystrophy and cone dystrophy","M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE+++M00090///Phosphatidylcholine (PC) biosynthesis, choline => PC","R04321///CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase   CDP-choline + 1-Alkyl-2-acetyl-sn-glycerol <=> CMP + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine+++R04922///CMP-N-trimethyl-2-aminoethylphosphonate:1,2-diacylglycerol (N-trimethyl-2-aminoethylphosphonyl)transferase   CMP-N-trimethyl-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate+++R02057///CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine+++R07389///1-Alkyl-2-acylglycerol + CDP-choline <=> 1-Radyl-2-acyl-sn-glycero-3-phosphocholine + CMP+++R04920///CMP-2-aminoethylphosphonate:1,2-diacylglycerol (2-aminoethylphosphonyl)transferase   CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate+++R07384///O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine+++R01321///CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase   CDP-choline + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylcholine+++R06364///CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine","GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane","GO:0004142///diacylglycerol cholinephosphotransferase activity+++GO:0046872///metal ion binding+++GO:0004307///ethanolaminephosphotransferase activity+++GO:0016740///transferase activity+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups","GO:0006656///phosphatidylcholine biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006657///CDP-choline pathway+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process","IPR014472///Choline/ethanolamine phosphotransferase+++IPR000462///CDP-alcohol phosphatidyltransferase","[CEPT1_HUMAN|Reviewed]RecName: Full=Choline/ethanolaminephosphotransferase 1; Short=hCEPT1; EC=2.7.8.1; EC=2.7.8.2;+++[A0A024R0C0_HUMAN|Unreviewed]SubName: Full=Choline/ethanolamine phosphotransferase 1, isoform CRA_b {ECO:0000313|EMBL:EAW56472.1};+++[A0A0C4DGS9_HUMAN|Unreviewed]SubName: Full=Choline/ethanolaminephosphotransferase 1 {ECO:0000313|Ensembl:ENSP00000477632};"]
[10391,"'CORO2B'",813,742,777.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding","GO:0030036///actin cytoskeleton organization","IPR036322///WD40-repeat-containing domain superfamily+++IPR015048///Domain of unknown function DUF1899+++IPR001680///WD40 repeat+++IPR027339///Coronin 2B+++IPR015505///Coronin+++IPR017986///WD40-repeat-containing domain+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR019775///WD40 repeat, conserved site","[COR2B_HUMAN|Reviewed]RecName: Full=Coronin-2B; AltName: Full=Coronin-like protein C; Short=Clipin-C; AltName: Full=Protein FC96;"]
[103910,"'MYL12B'",5977,4781,5379,"04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04530///Tight junction+++04810///Regulation of actin cytoskeleton+++04611///Platelet activation",{"$nulls":3},"GO:0099738///cell cortex region+++GO:0045177///apical part of cell+++GO:0005829///cytosol+++GO:0030018///Z disc+++GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005903///brush border+++GO:0001725///stress fiber+++GO:0070062///extracellular exosome","GO:0032036///myosin heavy chain binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0008360///regulation of cell shape","IPR018247///EF-Hand 1, calcium-binding site+++IPR015070///DJBP, EF-hand domain+++IPR002048///EF-hand domain+++IPR011992///EF-hand domain pair","[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;"]
[10392,"'NOD1'",61,47,54,"04621///NOD-like receptor signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05133///Pertussis+++05131///Shigellosis","H01358///Atopic dermatitis",null,"R03749///(5-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxoproline-forming) (5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid+++R02743///gamma-L-glutamyl-L-cysteine gamma-glutamyl cyclotransferase (5-oxoproline-forming) gamma-L-Glutamyl-L-cysteine <=> 5-Oxoproline + L-Cysteine","GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0042834///peptidoglycan binding+++GO:0050700///CARD domain binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0042802///identical protein binding","GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0000187///activation of MAPK activity+++GO:0002376///immune system process+++GO:0032731///positive regulation of interleukin-1 beta production+++GO:0032755///positive regulation of interleukin-6 production+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045087///innate immune response+++GO:0046330///positive regulation of JNK cascade+++GO:0009595///detection of biotic stimulus+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0016045///detection of bacterium+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0042981///regulation of apoptotic process+++GO:0007165///signal transduction+++GO:0042742///defense response to bacterium+++GO:1904417///positive regulation of xenophagy+++GO:0006915///apoptotic process+++GO:0071225///cellular response to muramyl dipeptide+++GO:0050830///defense response to Gram-positive bacterium+++GO:0007254///JNK cascade+++GO:0042228///interleukin-8 biosynthetic process+++GO:0006954///inflammatory response+++GO:0035556///intracellular signal transduction+++GO:0006952///defense response+++GO:0010942///positive regulation of cell death+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0002606///positive regulation of dendritic cell antigen processing and presentation+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051259///protein complex oligomerization+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily+++IPR011029///Death-like domain superfamily+++IPR007111///NACHT nucleoside triphosphatase+++IPR001315///CARD domain","[NOD1_HUMAN|Reviewed]RecName: Full=Nucleotide-binding oligomerization domain-containing protein 1; AltName: Full=Caspase recruitment domain-containing protein 4;+++[A0A024RA73_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4 {ECO:0000313|EMBL:EAL24453.1}; SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW93949.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 1 {ECO:0000313|EMBL:ALQ33972.1};+++[A0A0S2Z4W5_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 2 {ECO:0000313|EMBL:ALQ33973.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 3 {ECO:0000313|EMBL:ALQ33974.1}; SubName: Full=Nucleotide-binding oligomerization domain containing 1 isoform 4 {ECO:0000313|EMBL:ALQ33975.1};+++[A0A1B0GX71_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000399505}; Flags: Fragment;+++[C9J8X8_HUMAN|Unreviewed]SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000410917}; Flags: Fragment;+++[G3XAL1_HUMAN|Unreviewed]SubName: Full=Caspase recruitment domain family, member 4, isoform CRA_c {ECO:0000313|EMBL:EAW93948.1}; SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000416946};"]
[10393,"'ANAPC10'",49,54,51.5,"04114///Oocyte meiosis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04111///Cell cycle - yeast+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005680///anaphase-promoting complex","GO:0016887///ATPase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0005506///iron ion binding+++GO:0060698///endoribonuclease inhibitor activity+++GO:0043024///ribosomal small subunit binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding","GO:0007049///cell cycle+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0070979///protein K11-linked ubiquitination+++GO:0051301///cell division+++GO:0016567///protein ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition","IPR016901///Anaphase-promoting complex subunit APC10/Doc1+++IPR004939///APC10/DOC domain+++IPR008979///Galactose-binding-like domain superfamily","[APC10_HUMAN|Reviewed]RecName: Full=Anaphase-promoting complex subunit 10; Short=APC10; AltName: Full=Cyclosome subunit 10;+++[A0A286YEY6_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000493135};+++[D6R9Q5_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423223}; Flags: Fragment;+++[D6RA92_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000423043}; Flags: Fragment;+++[D6RB36_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000424463}; Flags: Fragment;+++[D6RD74_HUMAN|Unreviewed]SubName: Full=Anaphase-promoting complex subunit 10 {ECO:0000313|Ensembl:ENSP00000425459};+++[Q4W5I2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein APC10 {ECO:0000313|EMBL:AAY40941.1}; Flags: Fragment;"]
[10395,"'DLC1'",1228,1519,1373.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0071682///endocytic vesicle lumen+++GO:0031838///haptoglobin-hemoglobin complex+++GO:0070062///extracellular exosome+++GO:1904724///tertiary granule lumen+++GO:0005615///extracellular space+++GO:0072562///blood microparticle+++GO:0035580///specific granule lumen+++GO:0005576///extracellular region","GO:0004252///serine-type endopeptidase activity+++GO:0030492///hemoglobin binding+++GO:0016209///antioxidant activity+++GO:0005515///protein binding","GO:0042742///defense response to bacterium+++GO:0002376///immune system process+++GO:0042542///response to hydrogen peroxide+++GO:0006952///defense response+++GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis+++GO:0006953///acute-phase response+++GO:0098869///cellular oxidant detoxification+++GO:0043312///neutrophil degranulation+++GO:2000296///negative regulation of hydrogen peroxide catabolic process+++GO:0002526///acute inflammatory response+++GO:0010033///response to organic substance+++GO:0010942///positive regulation of cell death+++GO:0051354///negative regulation of oxidoreductase activity","IPR023393///START-like domain superfamily+++IPR028854///Rho GTPase-activating protein 7+++IPR008936///Rho GTPase activation protein+++IPR002913///START domain+++IPR000198///Rho GTPase-activating protein domain+++IPR001660///Sterile alpha motif domain+++IPR013761///Sterile alpha motif/pointed domain superfamily","[RHG07_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 7; AltName: Full=Deleted in liver cancer 1 protein; Short=DLC-1; AltName: Full=HP protein; AltName: Full=Rho-type GTPase-activating protein 7; AltName: Full=START domain-containing protein 12; Short=StARD12; AltName: Full=StAR-related lipid transfer protein 12;+++[A0A087WU08_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000478279};+++[A0A0J9YWS8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000488100}; Flags: Fragment;+++[A0A0U4DJF7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40940.1}; Flags: Fragment;+++[A0A0U4DKQ8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40945.1}; Flags: Fragment;+++[A0A0U4ERW6_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40957.1}; Flags: Fragment;+++[A0A0U4EXB4_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:ALX40958.1}; Flags: Fragment;+++[A0A2X0SYX6_HUMAN|Unreviewed]SubName: Full=DLC1 {ECO:0000313|EMBL:SPT35739.1}; Flags: Fragment;+++[A8K119_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76742, highly similar to Homo sapiens deleted in liver cancer 1 (DLC1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAF82423.1};+++[E5RI70_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000429537}; Flags: Fragment;+++[H0Y300_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000350406};+++[H3BMJ7_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000454413};+++[H3BS21_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000456503}; Flags: Fragment;+++[J3KRH2_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000461999}; Flags: Fragment;+++[J3KSV1_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000462662}; Flags: Fragment;+++[J3QLC9_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463491}; Flags: Fragment;+++[J3QQI8_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000463755};+++[J3QR68_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|Ensembl:ENSP00000464070}; Flags: Fragment;+++[Q14552_HUMAN|Unreviewed]SubName: Full=Haptoglobin {ECO:0000313|EMBL:AAA52686.1}; Flags: Fragment;+++[Q45XF9_HUMAN|Unreviewed]SubName: Full=Deleted in liver cancer 1 variant 2 {ECO:0000313|EMBL:AAZ32941.1}; Flags: Fragment;+++[Q6NSB4_HUMAN|Unreviewed]SubName: Full=HP protein {ECO:0000313|EMBL:AAH70299.1};+++[R4GMP5_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 7 {ECO:0000313|Ensembl:ENSP00000473289}; Flags: Fragment;"]
[10396,"'ATP8A1'",7,12,9.5,null,"H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0035579///specific granule membrane+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0005802///trans-Golgi network+++GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035577///azurophil granule membrane+++GO:0016020///membrane+++GO:0042584///chromaffin granule membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0004012///phospholipid-translocating ATPase activity+++GO:0005524///ATP binding+++GO:0019829///cation-transporting ATPase activity","GO:0030335///positive regulation of cell migration+++GO:0061092///positive regulation of phospholipid translocation+++GO:0034220///ion transmembrane transport+++GO:0045332///phospholipid translocation+++GO:0015914///phospholipid transport+++GO:0007612///learning+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0043312///neutrophil degranulation+++GO:0006869///lipid transport","IPR023298///P-type ATPase, transmembrane domain superfamily+++IPR032630///P-type ATPase, C-terminal+++IPR008250///P-type ATPase, A domain superfamily+++IPR032631///P-type ATPase, N-terminal+++IPR036412///HAD-like superfamily+++IPR018303///P-type ATPase, phosphorylation site+++IPR023214///HAD superfamily+++IPR006539///P-type ATPase, subfamily IV+++IPR023299///P-type ATPase, cytoplasmic domain N+++IPR001757///P-type ATPase","[AT8A1_HUMAN|Reviewed]RecName: Full=Phospholipid-transporting ATPase IA; EC=3.6.3.1; AltName: Full=ATPase class I type 8A member 1; AltName: Full=Chromaffin granule ATPase II; AltName: Full=P4-ATPase flippase complex alpha subunit ATP8A1;+++[H0Y8I6_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000421164}; Flags: Fragment;+++[H0YAA1_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426495}; Flags: Fragment;+++[H0YAF4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426935}; Flags: Fragment;+++[H0YAJ4_HUMAN|Unreviewed]SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000427295}; Flags: Fragment;+++[Q4G1C1_HUMAN|Unreviewed]SubName: Full=ATP8A1 protein {ECO:0000313|EMBL:AAH20943.1}; SubName: Full=Phospholipid-transporting ATPase IA {ECO:0000313|Ensembl:ENSP00000426636};"]
[10397,"'NDRG1'",260,219,239.5,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0005815///microtubule organizing center+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0005913///cell-cell adherens junction+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton","GO:0017137///Rab GTPase binding+++GO:0043015///gamma-tubulin binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0045576///mast cell activation+++GO:0007165///signal transduction+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0099173///postsynapse organization+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0071456///cellular response to hypoxia+++GO:0042981///regulation of apoptotic process+++GO:0008285///negative regulation of cell proliferation+++GO:0010038///response to metal ion+++GO:0042127///regulation of cell proliferation","IPR029058///Alpha/Beta hydrolase fold+++IPR030693///Protein NDRG1+++IPR004142///NDRG","[NDRG1_HUMAN|Reviewed]RecName: Full=Protein NDRG1; AltName: Full=Differentiation-related gene 1 protein; Short=DRG-1; AltName: Full=N-myc downstream-regulated gene 1 protein; AltName: Full=Nickel-specific induction protein Cap43; AltName: Full=Reducing agents and tunicamycin-responsive protein; Short=RTP; AltName: Full=Rit42;+++[A0A024R9I3_HUMAN|Unreviewed]SubName: Full=N-myc downstream regulated gene 1, isoform CRA_b {ECO:0000313|EMBL:EAW92166.1};+++[B3KWB2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ42719 fis, clone BRAMY3010492, highly similar to Protein NDRG1 {ECO:0000313|EMBL:BAG54074.1};+++[E5RG99_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428802}; Flags: Fragment;+++[E5RGG6_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000430171}; Flags: Fragment;+++[E5RGM5_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429994}; Flags: Fragment;+++[E5RH82_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429840}; Flags: Fragment;+++[E5RI76_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429524}; Flags: Fragment;+++[E5RIM2_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429380};+++[E5RIR1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428384}; Flags: Fragment;+++[E5RIV1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428345}; Flags: Fragment;+++[E5RJ98_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429172};+++[E5RJY1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000431057};+++[E5RK17_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000428991}; Flags: Fragment;+++[E7ESM1_HUMAN|Unreviewed]SubName: Full=Protein NDRG1 {ECO:0000313|Ensembl:ENSP00000429007};+++[Q8N959_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38330 fis, clone FCBBF3025280, highly similar to NDRG1 PROTEIN {ECO:0000313|EMBL:BAC04597.1};"]
[10398,"'MYL9'",46895,43104,44999.5,"04670///Leukocyte transendothelial migration+++04270///Vascular smooth muscle contraction+++04530///Tight junction+++04921///Oxytocin signaling pathway+++04024///cAMP signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016460///myosin II complex+++GO:0016459///myosin complex+++GO:0005829///cytosol+++GO:0001725///stress fiber+++GO:0030018///Z disc+++GO:0005859///muscle myosin complex","GO:0046872///metal ion binding+++GO:0008307///structural constituent of muscle+++GO:0032036///myosin heavy chain binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0006937///regulation of muscle contraction+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0070527///platelet aggregation","IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain+++IPR018247///EF-Hand 1, calcium-binding site","[MYL9_HUMAN|Reviewed]RecName: Full=Myosin regulatory light polypeptide 9; AltName: Full=20 kDa myosin light chain; Short=LC20; AltName: Full=MLC-2C; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 9; AltName: Full=Myosin regulatory light chain MRLC1;+++[Q6IBG1_HUMAN|Unreviewed]SubName: Full=MYL9 protein {ECO:0000313|EMBL:CAG33124.1};"]
[10399,"'RACK1'",16403,12866,14634.5,"05162///Measles",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0005840///ribosome+++GO:1990630///IRE1-RACK1-PP2A complex+++GO:0001891///phagocytic cup+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0015935///small ribosomal subunit+++GO:0042995///cell projection+++GO:0005654///nucleoplasm+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0044297///cell body+++GO:0030496///midbody+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0043204///perikaryon+++GO:0022627///cytosolic small ribosomal subunit+++GO:0030425///dendrite+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0045296///cadherin binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0003723///RNA binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0008200///ion channel inhibitor activity+++GO:0030292///protein tyrosine kinase inhibitor activity+++GO:0043022///ribosome binding+++GO:0042169///SH2 domain binding+++GO:0005080///protein kinase C binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0019899///enzyme binding+++GO:0030332///cyclin binding+++GO:0019903///protein phosphatase binding+++GO:0035591///signaling adaptor activity+++GO:0042803///protein homodimerization activity","GO:0072344///rescue of stalled ribosome+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0032464///positive regulation of protein homooligomerization+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006412///translation+++GO:0071363///cellular response to growth factor stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:1900102///negative regulation of endoplasmic reticulum unfolded protein response+++GO:0017148///negative regulation of translation+++GO:0032880///regulation of protein localization+++GO:0051901///positive regulation of mitochondrial depolarization+++GO:0043065///positive regulation of apoptotic process+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0007369///gastrulation+++GO:0040008///regulation of growth+++GO:0016567///protein ubiquitination+++GO:0030308///negative regulation of cell growth+++GO:0050765///negative regulation of phagocytosis+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0048511///rhythmic process+++GO:0043547///positive regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0006915///apoptotic process+++GO:2000304///positive regulation of ceramide biosynthetic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0010629///negative regulation of gene expression+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0007049///cell cycle+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0042998///positive regulation of Golgi to plasma membrane protein transport+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:0006417///regulation of translation+++GO:2000543///positive regulation of gastrulation+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0051726///regulation of cell cycle+++GO:0051302///regulation of cell division+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0043473///pigmentation+++GO:0071333///cellular response to glucose stimulus","IPR036322///WD40-repeat-containing domain superfamily+++IPR001680///WD40 repeat+++IPR020472///G-protein beta WD-40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR019775///WD40 repeat, conserved site+++IPR017986///WD40-repeat-containing domain","[RACK1_HUMAN|Reviewed]RecName: Full=Receptor of activated protein C kinase 1; AltName: Full=Cell proliferation-inducing gene 21 protein; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1; AltName: Full=Guanine nucleotide-binding protein subunit beta-like protein 12.3; AltName: Full=Human lung cancer oncogene 7 protein; Short=HLC-7; AltName: Full=Receptor for activated C kinase; AltName: Full=Small ribosomal subunit protein RACK1 {ECO:0000303|PubMed:24524803}; Contains: RecName: Full=Receptor of activated protein C kinase 1, N-terminally processed; AltName: Full=Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed;+++[D6R909_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422198};+++[D6R9L0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000423569}; Flags: Fragment;+++[D6R9Z1_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422029}; Flags: Fragment;+++[D6RAC2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422768};+++[D6RAU2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424760};+++[D6RBD0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424237}; Flags: Fragment;+++[D6RDI0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000420936};+++[D6REE5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000425008}; Flags: Fragment;+++[D6RF23_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426708};+++[D6RFX4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421416}; Flags: Fragment;+++[D6RFZ9_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421356}; Flags: Fragment;+++[D6RGK8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426270};+++[D6RHH4_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426101};+++[D6RHJ5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426046};+++[E9KL35_HUMAN|Unreviewed]SubName: Full=Epididymis tissue sperm binding protein Li 3a {ECO:0000313|EMBL:ADU87634.1};+++[E9PD14_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426111};+++[H0Y8R5_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000421838}; Flags: Fragment;+++[H0Y8W2_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000422316}; Flags: Fragment;+++[H0Y9P0_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000424654}; Flags: Fragment;+++[H0YAF8_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000426960}; Flags: Fragment;+++[H0YAM7_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000427677}; Flags: Fragment;+++[I3QNU9_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein beta polypeptide 2-like 1 {ECO:0000313|EMBL:AFK13122.1}; Flags: Fragment;+++[J3KPE3_HUMAN|Unreviewed]SubName: Full=Receptor of-activated protein C kinase 1 {ECO:0000313|Ensembl:ENSP00000366013};"]
[104,"'ADARB1'",191,235,213,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005737///cytoplasm","GO:0008251///tRNA-specific adenosine deaminase activity+++GO:0003725///double-stranded RNA binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003729///mRNA binding+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding+++GO:0004000///adenosine deaminase activity","GO:0006382///adenosine to inosine editing+++GO:0051726///regulation of cell cycle+++GO:0051607///defense response to virus+++GO:0021610///facial nerve morphogenesis+++GO:0061744///motor behavior+++GO:0050884///neuromuscular process controlling posture+++GO:0030336///negative regulation of cell migration+++GO:0007274///neuromuscular synaptic transmission+++GO:0008285///negative regulation of cell proliferation+++GO:0006396///RNA processing+++GO:0035264///multicellular organism growth+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0097049///motor neuron apoptotic process+++GO:0060384///innervation+++GO:0006397///mRNA processing+++GO:0021618///hypoglossal nerve morphogenesis+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0060415///muscle tissue morphogenesis+++GO:0021965///spinal cord ventral commissure morphogenesis+++GO:0045087///innate immune response+++GO:0016553///base conversion or substitution editing","IPR002466///Adenosine deaminase/editase+++IPR014720///Double-stranded RNA-binding domain+++IPR008996///Cytokine IL1/FGF","[RED1_HUMAN|Reviewed]RecName: Full=Double-stranded RNA-specific editase 1; EC=3.5.4.37; AltName: Full=RNA-editing deaminase 1; AltName: Full=RNA-editing enzyme 1; AltName: Full=dsRNA adenosine deaminase;+++[A0A0A0MSG8_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000387480}; Flags: Fragment;+++[Q86XN4_HUMAN|Unreviewed]SubName: Full=RNA adenosine deaminase {ECO:0000313|EMBL:AAB18134.1};+++[Q8TCX7_HUMAN|Unreviewed]SubName: Full=Double-stranded RNA-specific editase 1 {ECO:0000313|Ensembl:ENSP00000478160}; SubName: Full=HCG2008433 {ECO:0000313|EMBL:EAX09362.1};"]
[1040,"'CDS1'",64,62,63,"04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism",null,"M00093///Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE","R01799///CTP:phosphatidate cytidyltransferase   CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol","GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0004142///diacylglycerol cholinephosphotransferase activity","GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0007602///phototransduction+++GO:0007165///signal transduction+++GO:0006661///phosphatidylinositol biosynthetic process","IPR016720///Phosphatidate cytidylyltransferase, eukaryota+++IPR000374///Phosphatidate cytidylyltransferase","[CDS1_HUMAN|Reviewed]RecName: Full=Phosphatidate cytidylyltransferase 1; EC=2.7.7.41; AltName: Full=CDP-DAG synthase 1; AltName: Full=CDP-DG synthase 1; AltName: Full=CDP-diacylglycerol synthase 1; Short=CDS 1; AltName: Full=CDP-diglyceride pyrophosphorylase 1; AltName: Full=CDP-diglyceride synthase 1; AltName: Full=CTP:phosphatidate cytidylyltransferase 1;+++[A0A024RDG8_HUMAN|Unreviewed]RecName: Full=Phosphatidate cytidylyltransferase {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938}; EC=2.7.7.41 {ECO:0000256|PIRNR:PIRNR018269, ECO:0000256|RuleBase:RU003938};"]
[10400,"'PEMT'",663,486,574.5,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites",null,"M00091///Phosphatidylcholine (PC) biosynthesis, PE => PC","R03424///S-adenosyl-L-methionine:phosphatidyl-N-methylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-methylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-dimethylethanolamine+++R02056///S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidyl-N-methylethanolamine+++R01320///S-adenosyl-L-methionine:phosphatidyl-N-dimethylethanolamine N-methyltransferase   S-Adenosyl-L-methionine + Phosphatidyl-N-dimethylethanolamine <=> S-Adenosyl-L-homocysteine + Phosphatidylcholine","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0004603///phenylethanolamine N-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0042423///catecholamine biosynthetic process+++GO:0032259///methylation+++GO:0042418///epinephrine biosynthetic process","IPR024960///Phosphatidyl-N-methylethanolamine/Phosphatidylethanolamine N-methyltransferase+++IPR007318///Phospholipid methyltransferase","[PEMT_HUMAN|Reviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000255|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000255|HAMAP-Rule:MF_03216}; AltName: Full=PEMT2; AltName: Full=Phospholipid methyltransferase {ECO:0000255|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000255|HAMAP-Rule:MF_03216};+++[D3YTC7_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};+++[J3KTR2_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463112};+++[J3QLU8_HUMAN|Unreviewed]SubName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000463713};+++[J3QRI3_HUMAN|Unreviewed]SubName: Full=Phenylethanolamine N-methyltransferase {ECO:0000313|Ensembl:ENSP00000464234};+++[Q6FHD9_HUMAN|Unreviewed]SubName: Full=PNMT protein {ECO:0000313|EMBL:CAG46614.1};+++[Q71UY0_HUMAN|Unreviewed]RecName: Full=Phosphatidylethanolamine N-methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEAMT {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PEMT {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.17 {ECO:0000256|HAMAP-Rule:MF_03216}; EC=2.1.1.71 {ECO:0000256|HAMAP-Rule:MF_03216}; AltName: Full=Phospholipid methyltransferase {ECO:0000256|HAMAP-Rule:MF_03216}; Short=PLMT {ECO:0000256|HAMAP-Rule:MF_03216};"]
[10401,"'PIAS3'",851,1102,976.5,"04120///Ubiquitin mediated proteolysis+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0030425///dendrite+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0045202///synapse+++GO:0005634///nucleus","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0015459///potassium channel regulator activity+++GO:0051059///NF-kappaB binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0019789///SUMO transferase activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0047485///protein N-terminus binding","GO:0009725///response to hormone+++GO:0071847///TNFSF11-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010629///negative regulation of gene expression+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010628///positive regulation of gene expression+++GO:0033234///negative regulation of protein sumoylation+++GO:0033235///positive regulation of protein sumoylation+++GO:0045838///positive regulation of membrane potential+++GO:0016925///protein sumoylation","IPR027228///E3 SUMO-protein ligase PIAS2+++IPR038654///PINIT domain superfamily+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR036361///SAP domain superfamily+++IPR023321///PINIT domain+++IPR027226///E3 SUMO-protein ligase PIAS3+++IPR004181///Zinc finger, MIZ-type+++IPR003034///SAP domain","[PIAS3_HUMAN|Reviewed]RecName: Full=E3 SUMO-protein ligase PIAS3; EC=2.3.2.-; AltName: Full=E3 SUMO-protein transferase PIAS3 {ECO:0000305}; AltName: Full=Protein inhibitor of activated STAT protein 3;+++[B3KNI3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14651 fis, clone NT2RP2002193, highly similar to Protein inhibitor of activated STAT protein 3 {ECO:0000313|EMBL:BAG51345.1};+++[E7ESB4_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000376766}; Flags: Fragment;+++[E9PHH8_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000358304};+++[Q6IAR4_HUMAN|Unreviewed]SubName: Full=PIAS3 protein {ECO:0000313|EMBL:CAG33371.1}; SubName: Full=Protein inhibitor of activated STAT3 {ECO:0000313|EMBL:AAP35684.1};+++[U3KQV1_HUMAN|Unreviewed]SubName: Full=E3 SUMO-protein ligase PIAS3 {ECO:0000313|Ensembl:ENSP00000476245}; Flags: Fragment;"]
[10402,"'ST3GAL6'",1,2,1.5,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++01100///Metabolic pathways",null,null,"R06026///CMP-N-acetylneuraminate + Paragloboside <=> CMP + Sialyl-3-paragloboside+++R06037///CMP-N-acetylneuraminate + nLc6Cer <=> CMP + VI3NeuAc-nLc6Cer","GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008373///sialyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003836///beta-galactoside (CMP) alpha-2,3-sialyltransferase activity+++GO:0052798///beta-galactoside alpha-2,3-sialyltransferase activity","GO:0006464///cellular protein modification process+++GO:0006486///protein glycosylation+++GO:0071354///cellular response to interleukin-6+++GO:0009311///oligosaccharide metabolic process+++GO:0006664///glycolipid metabolic process+++GO:0009247///glycolipid biosynthetic process+++GO:0097503///sialylation+++GO:0018146///keratan sulfate biosynthetic process","IPR012163///Sialyltransferase+++IPR038578///GT29-like superfamiliy+++IPR001675///Glycosyl transferase family 29","[SIA10_HUMAN|Reviewed]RecName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase; EC=2.4.99.-; AltName: Full=CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI; AltName: Full=ST3Gal VI; Short=ST3GalVI; AltName: Full=Sialyltransferase 10;+++[A0A087WXB8_HUMAN|Unreviewed]SubName: Full=ST3 beta-galactoside alpha-2,3-sialyltransferase 6, isoform CRA_b {ECO:0000313|EMBL:EAW79851.1}; SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000480884};+++[C9IZL6_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418650}; Flags: Fragment;+++[C9J0E2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418896}; Flags: Fragment;+++[C9J480_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417201}; Flags: Fragment;+++[C9J9Y4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417584}; Flags: Fragment;+++[C9JMW7_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000420474};+++[C9JWI9_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419209}; Flags: Fragment;+++[C9JWJ3_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419202}; Flags: Fragment;+++[C9JXM2_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000419987}; Flags: Fragment;+++[F2Z2F4_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000417109};+++[F8WC98_HUMAN|Unreviewed]SubName: Full=Type 2 lactosamine alpha-2,3-sialyltransferase {ECO:0000313|Ensembl:ENSP00000418581};"]
[10403,"'NDC80'",1,0,0.5,{"$nulls":4},"GO:0005694///chromosome+++GO:0031262///Ndc80 complex+++GO:0005829///cytosol+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0005813///centrosome+++GO:0005634///nucleus+++GO:0000776///kinetochore+++GO:0000775///chromosome, centromeric region+++GO:0000942///condensed nuclear chromosome outer kinetochore+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0000777///condensed chromosome kinetochore","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0051383///kinetochore organization+++GO:1905342///positive regulation of protein localization to kinetochore+++GO:0000070///mitotic sister chromatid segregation+++GO:0000278///mitotic cell cycle+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0007059///chromosome segregation+++GO:0008608///attachment of spindle microtubules to kinetochore+++GO:0007049///cell cycle+++GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0051301///cell division+++GO:0090267///positive regulation of mitotic cell cycle spindle assembly checkpoint+++GO:0000132///establishment of mitotic spindle orientation","IPR038273///Ndc80 domain superfamily+++IPR005550///Kinetochore protein Ndc80","[NDC80_HUMAN|Reviewed]RecName: Full=Kinetochore protein NDC80 homolog; AltName: Full=Highly expressed in cancer protein; AltName: Full=Kinetochore protein Hec1; Short=HsHec1; AltName: Full=Kinetochore-associated protein 2; AltName: Full=Retinoblastoma-associated protein HEC;+++[A8K031_HUMAN|Unreviewed]SubName: Full=Kinetochore associated 2, isoform CRA_a {ECO:0000313|EMBL:EAX01696.1}; SubName: Full=NDC80 homolog, kinetochore complex component (S. cerevisiae) {ECO:0000313|EMBL:AAH35617.1}; SubName: Full=cDNA FLJ77925, highly similar to Homo sapiens kinetochore associated 2, mRNA {ECO:0000313|EMBL:BAF82085.1}; SubName: Full=cDNA, FLJ93683, Homo sapiens kinetochore associated 2 (KNTC2), mRNA {ECO:0000313|EMBL:BAG36001.1};+++[I3L0P0_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000458236}; Flags: Fragment;+++[I3L4G3_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000461227}; Flags: Fragment;+++[Q05DQ6_HUMAN|Unreviewed]SubName: Full=NDC80 protein {ECO:0000313|EMBL:AAH05239.1}; Flags: Fragment;+++[V9GYM9_HUMAN|Unreviewed]SubName: Full=Kinetochore protein NDC80 homolog {ECO:0000313|Ensembl:ENSP00000476919}; Flags: Fragment;"]
[10404,"'CPQ'",241,233,237,{"$nulls":4},"GO:0005615///extracellular space+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0042803///protein homodimerization activity+++GO:0008233///peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0070573///metallodipeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding","GO:0042246///tissue regeneration+++GO:0043171///peptide catabolic process+++GO:0006508///proteolysis+++GO:0006590///thyroid hormone generation","IPR007484///Peptidase M28+++IPR039866///Carboxypeptidase Q","[CBPQ_HUMAN|Reviewed]RecName: Full=Carboxypeptidase Q; EC=3.4.17.-; AltName: Full=Lysosomal dipeptidase; AltName: Full=Plasma glutamate carboxypeptidase; Flags: Precursor;+++[A0A024R9B8_HUMAN|Unreviewed]SubName: Full=Plasma glutamate carboxypeptidase, isoform CRA_a {ECO:0000313|EMBL:EAW91758.1};+++[E5RH35_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429934}; Flags: Fragment;+++[E5RJA8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429146}; Flags: Fragment;+++[E5RJP8_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431114}; Flags: Fragment;+++[E5RJZ7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000431024}; Flags: Fragment;+++[H0YBB7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase Q {ECO:0000313|Ensembl:ENSP00000429134}; Flags: Fragment;"]
[10406,"'WFDC2'",15,2,8.5,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0004866///endopeptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0019828///aspartic-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010951///negative regulation of endopeptidase activity+++GO:0006508///proteolysis+++GO:0007283///spermatogenesis+++GO:0010466///negative regulation of peptidase activity","IPR036645///Elafin-like superfamily+++IPR008197///WAP-type 'four-disulfide core' domain","[WFDC2_HUMAN|Reviewed]RecName: Full=WAP four-disulfide core domain protein 2; AltName: Full=Epididymal secretory protein E4; AltName: Full=Major epididymis-specific protein E4; AltName: Full=Putative protease inhibitor WAP5; Flags: Precursor;+++[A8K2M3_HUMAN|Unreviewed]SubName: Full=WAP four-disulfide core domain 2, isoform CRA_c {ECO:0000313|EMBL:EAW75838.1}; SubName: Full=WAP four-disulfide core domain protein 2 {ECO:0000313|Ensembl:ENSP00000404760}; SubName: Full=cDNA FLJ76533, highly similar to Homo sapiens WAP four-disulfide core domain 2 (WFDC2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAF82977.1};"]
[10408,"'MYCNOS'",0,1,0.5,"05202///Transcriptional misregulation in cancer","H00510///Feingold syndrome+++H00043///Neuroblastoma",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0031647///regulation of protein stability+++GO:0033673///negative regulation of kinase activity+++GO:0007275///multicellular organism development+++GO:0008284///positive regulation of cell proliferation",null,"[NCYM_HUMAN|Reviewed]RecName: Full=N-cym protein; AltName: Full=N-myc opposite strand;"]
[10409,"'BASP1'",5146,3536,4341,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0030426///growth cone+++GO:0031982///vesicle+++GO:0005856///cytoskeleton+++GO:0016607///nuclear speck+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome","GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0019904///protein domain specific binding","GO:0060421///positive regulation of heart growth+++GO:0060539///diaphragm development+++GO:0021762///substantia nigra development+++GO:0072075///metanephric mesenchyme development+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:2001076///positive regulation of metanephric ureteric bud development+++GO:0007356///thorax and anterior abdomen determination+++GO:0060231///mesenchymal to epithelial transition+++GO:0008406///gonad development+++GO:0045892///negative regulation of transcription, DNA-templated","IPR008408///Brain acid soluble protein 1","[BASP1_HUMAN|Reviewed]RecName: Full=Brain acid soluble protein 1; AltName: Full=22 kDa neuronal tissue-enriched acidic protein; AltName: Full=Neuronal axonal membrane protein NAP-22;+++[U3KQP0_HUMAN|Unreviewed]SubName: Full=Brain acid soluble protein 1 {ECO:0000313|Ensembl:ENSP00000476090}; Flags: Fragment;"]
[1041,"'CDSN'",94,56,75,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0001533///cornified envelope+++GO:0030057///desmosome+++GO:0005911///cell-cell junction","GO:0042803///protein homodimerization activity","GO:0008544///epidermis development+++GO:0070268///cornification+++GO:0030216///keratinocyte differentiation+++GO:0003336///corneocyte desquamation+++GO:0007155///cell adhesion+++GO:1905716///negative regulation of cornification+++GO:0043589///skin morphogenesis+++GO:0098609///cell-cell adhesion","IPR026087///Corneodesmosin","[CDSN_HUMAN|Reviewed]RecName: Full=Corneodesmosin; AltName: Full=S protein; Flags: Precursor;+++[D2IYL2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77254.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:ACZ95707.1};+++[G8JLG2_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77255.1}; SubName: Full=Corneodesmosin {ECO:0000313|Ensembl:ENSP00000365465};+++[M1SWB8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77250.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AGG40963.1};+++[Q0EFA5_HUMAN|Unreviewed]SubName: Full=S protein {ECO:0000313|EMBL:BAF31283.1};+++[Q2L6G8_HUMAN|Unreviewed]SubName: Full=CDSN {ECO:0000313|EMBL:AQY77252.1}; SubName: Full=Corneodesmosin {ECO:0000313|EMBL:BAE78625.1, ECO:0000313|Ensembl:ENSP00000373023};+++[Q7Z559_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94641.1}; Flags: Fragment;+++[Q7Z560_HUMAN|Unreviewed]SubName: Full=Corneodesmosin {ECO:0000313|EMBL:AAP94640.1}; Flags: Fragment;"]
[10410,"'IFITM3'",34138.99,27888.35,31013.67,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0032991///protein-containing complex+++GO:0005768///endosome+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0060337///type I interferon signaling pathway+++GO:0032897///negative regulation of viral transcription+++GO:0002376///immune system process+++GO:0034341///response to interferon-gamma+++GO:0035455///response to interferon-alpha+++GO:0035456///response to interferon-beta+++GO:0046597///negative regulation of viral entry into host cell+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0006955///immune response+++GO:0009615///response to virus+++GO:0051607///defense response to virus","IPR007593///CD225/Dispanin family","[IFM3_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 3; AltName: Full=Dispanin subfamily A member 2b; Short=DSPA2b; AltName: Full=Interferon-inducible protein 1-8U;+++[E9PS44_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000432108};+++[H9NKY4_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60318.1};+++[H9NL12_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60346.1};+++[H9NL19_HUMAN|Unreviewed]SubName: Full=IFITM3 {ECO:0000313|EMBL:AFF60353.1};+++[R4GNG9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 3 {ECO:0000313|Ensembl:ENSP00000473645}; Flags: Fragment;"]
[10411,"'RAPGEF3'",41,67,54,"04015///Rap1 signaling pathway+++04072///Phospholipase D signaling pathway+++04720///Long-term potentiation+++04726///Serotonergic synapse+++04670///Leukocyte transendothelial migration+++04261///Adrenergic signaling in cardiomyocytes+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005902///microvillus+++GO:0030864///cortical actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0016020///membrane+++GO:0012505///endomembrane system+++GO:0030175///filopodium","GO:0005515///protein binding+++GO:0030552///cAMP binding+++GO:0000166///nucleotide binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0019904///protein domain specific binding+++GO:0017034///Rap guanyl-nucleotide exchange factor activity","GO:0019933///cAMP-mediated signaling+++GO:0035556///intracellular signal transduction+++GO:0051496///positive regulation of stress fiber assembly+++GO:0007264///small GTPase mediated signal transduction+++GO:0034242///negative regulation of syncytium formation by plasma membrane fusion+++GO:1901985///positive regulation of protein acetylation+++GO:0071320///cellular response to cAMP+++GO:0050796///regulation of insulin secretion+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000249///regulation of actin cytoskeleton reorganization+++GO:0032486///Rap protein signal transduction+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:0061028///establishment of endothelial barrier+++GO:2000615///regulation of histone H3-K9 acetylation+++GO:0008283///cell proliferation+++GO:0007165///signal transduction+++GO:0046827///positive regulation of protein export from nucleus+++GO:0043547///positive regulation of GTPase activity+++GO:0060143///positive regulation of syncytium formation by plasma membrane fusion","IPR000595///Cyclic nucleotide-binding domain+++IPR008937///Ras-like guanine nucleotide exchange factor+++IPR036964///Ras guanine-nucleotide exchange factor catalytic domain superfamily+++IPR018490///Cyclic nucleotide-binding-like+++IPR001895///Ras guanine-nucleotide exchange factors catalytic domain+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR000591///DEP domain+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR014710///RmlC-like jelly roll fold+++IPR000651///Ras-like guanine nucleotide exchange factor, N-terminal+++IPR023578///Ras guanine nucleotide exchange factor domain superfamily+++IPR019804///Ras guanine-nucleotide exchange factor, conserved site+++IPR029071///Ubiquitin-like domain superfamily","[RPGF3_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 3; AltName: Full=Exchange factor directly activated by cAMP 1; AltName: Full=Exchange protein directly activated by cAMP 1; Short=EPAC 1; AltName: Full=Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; AltName: Full=cAMP-regulated guanine nucleotide exchange factor I; Short=cAMP-GEFI;+++[F8VRX1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448480};+++[F8VVJ6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449905};+++[F8VXK1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000448804}; Flags: Fragment;+++[F8W0N0_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000446731}; Flags: Fragment;+++[H0YHS2_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000447691}; Flags: Fragment;+++[H0YIP6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSP00000449818}; Flags: Fragment;+++[Q569L6_HUMAN|Unreviewed]SubName: Full=RAPGEF3 protein {ECO:0000313|EMBL:AAH92404.2};+++[Q99777_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAB50216.1}; Flags: Fragment;"]
[10412,"'NSA2'",925,660,792.5,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing","IPR022309///Ribosomal protein S8e/ribosomal biogenesis NSA2+++IPR039411///Ribosomal biogenesis NSA2 family","[NSA2_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein NSA2 homolog; AltName: Full=Hairy cell leukemia protein 1; AltName: Full=TGF-beta-inducible nuclear protein 1;+++[A0A0A0MQZ6_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000296802};+++[H0YAI9_HUMAN|Unreviewed]SubName: Full=Ribosome biogenesis protein NSA2 homolog {ECO:0000313|Ensembl:ENSP00000427266}; Flags: Fragment;+++[Q5J7U2_HUMAN|Unreviewed]SubName: Full=TGF beta-inducible nuclear protein 1 {ECO:0000313|EMBL:EAW95749.1}; SubName: Full=TGF-beta inducible nuclear protein {ECO:0000313|EMBL:AAS00024.1}; SubName: Full=cDNA, FLJ94393, Homo sapiens TGF beta-inducible nuclear protein 1 (TINP1), mRNA {ECO:0000313|EMBL:BAG36522.1};"]
[10413,"'YAP1'",1054,1425,1239.5,"04391///Hippo signaling pathway - fly+++04390///Hippo signaling pathway+++04392///Hippo signaling pathway - multiple species",null,"M00683///Hippo signaling",null,"GO:0005737///cytoplasm+++GO:0071148///TEAD-1-YAP complex+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0071149///TEAD-2-YAP complex","GO:0046982///protein heterodimerization activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0070064///proline-rich region binding+++GO:0033613///activating transcription factor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0008022///protein C-terminus binding+++GO:0003714///transcription corepressor activity","GO:0010468///regulation of gene expression+++GO:0035019///somatic stem cell population maintenance+++GO:0048368///lateral mesoderm development+++GO:0030903///notochord development+++GO:0042127///regulation of cell proliferation+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0001570///vasculogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0048339///paraxial mesoderm development+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0035329///hippo signaling+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:2000737///negative regulation of stem cell differentiation+++GO:0060242///contact inhibition+++GO:0010837///regulation of keratinocyte proliferation+++GO:0060449///bud elongation involved in lung branching+++GO:0072091///regulation of stem cell proliferation+++GO:0032570///response to progesterone+++GO:0060487///lung epithelial cell differentiation+++GO:0008283///cell proliferation+++GO:0061026///cardiac muscle tissue regeneration+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006974///cellular response to DNA damage stimulus+++GO:1902459///positive regulation of stem cell population maintenance+++GO:0046622///positive regulation of organ growth+++GO:0050767///regulation of neurogenesis+++GO:0003015///heart process+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0072307///regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0003143///embryonic heart tube morphogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001894///tissue homeostasis+++GO:0008284///positive regulation of cell proliferation+++GO:0071300///cellular response to retinoic acid+++GO:0030216///keratinocyte differentiation+++GO:0050847///progesterone receptor signaling pathway+++GO:0071480///cellular response to gamma radiation+++GO:0065003///protein-containing complex assembly","IPR001202///WW domain+++IPR036020///WW domain superfamily","[YAP1_HUMAN|Reviewed]RecName: Full=Transcriptional coactivator YAP1; Short=Yes-associated protein 1; AltName: Full=Protein yorkie homolog; AltName: Full=Yes-associated protein YAP65 homolog;+++[A0A024R3E4_HUMAN|Unreviewed]SubName: Full=Yes-associated protein 1, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW67014.1};+++[H0YCI3_HUMAN|Unreviewed]SubName: Full=Transcriptional coactivator YAP1 {ECO:0000313|Ensembl:ENSP00000431626}; Flags: Fragment;+++[K0KVU2_HUMAN|Unreviewed]SubName: Full=Yes-associated protein isoform 9 {ECO:0000313|EMBL:CCI79622.1}; Flags: Fragment;+++[Q86T74_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451O0517 {ECO:0000313|EMBL:CAD89963.1}; Flags: Fragment;"]
[10417,"'SPON2'",53,50,51.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0001530///lipopolysaccharide binding+++GO:0003823///antigen binding","GO:0007411///axon guidance+++GO:0071222///cellular response to lipopolysaccharide+++GO:0045087///innate immune response+++GO:0032755///positive regulation of interleukin-6 production+++GO:0002448///mast cell mediated immunity+++GO:0008228///opsonization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0051607///defense response to virus+++GO:0032496///response to lipopolysaccharide+++GO:0007155///cell adhesion+++GO:0043152///induction of bacterial agglutination+++GO:0042742///defense response to bacterium+++GO:0050832///defense response to fungus+++GO:0060907///positive regulation of macrophage cytokine production+++GO:0002376///immune system process","IPR000884///Thrombospondin type-1 (TSP1) repeat+++IPR009465///Spondin, N-terminal+++IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR038678///Spondin, N-terminal domain superfamily","[SPON2_HUMAN|Reviewed]RecName: Full=Spondin-2; AltName: Full=Differentially expressed in cancerous and non-cancerous lung cells 1; Short=DIL-1; AltName: Full=Mindin; Flags: Precursor;+++[A0A1Y8ELY7_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421858}; Flags: Fragment;+++[D6RA41_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000423414}; Flags: Fragment;+++[D6RB12_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000424542}; Flags: Fragment;+++[D6RBY3_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000422516}; Flags: Fragment;+++[D6REX2_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421634}; Flags: Fragment;+++[D6RFY9_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000421379}; Flags: Fragment;+++[D6RIH5_HUMAN|Unreviewed]SubName: Full=Spondin-2 {ECO:0000313|Ensembl:ENSP00000425871}; Flags: Fragment;"]
[10419,"'PRMT5'",1230,1271,1250.5,"04111///Cell cycle - yeast+++04011///MAPK signaling pathway - yeast+++03013///RNA transport",null,null,"R11220///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine+++R11218///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)'-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)'-dimethyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0035097///histone methyltransferase complex+++GO:0005737///cytoplasm+++GO:0034709///methylosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046982///protein heterodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0008327///methyl-CpG binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0035243///protein-arginine omega-N symmetric methyltransferase activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0003714///transcription corepressor activity+++GO:0016274///protein-arginine N-methyltransferase activity+++GO:0044020///histone methyltransferase activity (H4-R3 specific)+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0070888///E-box binding+++GO:0005515///protein binding","GO:0006325///chromatin organization+++GO:1904992///positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway+++GO:0044030///regulation of DNA methylation+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0042118///endothelial cell activation+++GO:0000387///spliceosomal snRNP assembly+++GO:0097421///liver regeneration+++GO:0043985///histone H4-R3 methylation+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0018216///peptidyl-arginine methylation+++GO:0008283///cell proliferation+++GO:0006479///protein methylation+++GO:0045596///negative regulation of cell differentiation+++GO:0048511///rhythmic process+++GO:0006353///DNA-templated transcription, termination+++GO:0032922///circadian regulation of gene expression+++GO:0019918///peptidyl-arginine methylation, to symmetrical-dimethyl arginine+++GO:0035246///peptidyl-arginine N-methylation+++GO:0032259///methylation+++GO:0048714///positive regulation of oligodendrocyte differentiation+++GO:0034969///histone arginine methylation+++GO:0007088///regulation of mitotic nuclear division+++GO:0090161///Golgi ribbon formation","IPR035075///PRMT5 arginine-N-methyltransferase+++IPR035248///PRMT5, oligomerisation domain+++IPR007857///Protein arginine N-methyltransferase PRMT5+++IPR035247///PRMT5, TIM barrel domain+++IPR025799///Protein arginine N-methyltransferase+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[ANM5_HUMAN|Reviewed]RecName: Full=Protein arginine N-methyltransferase 5; EC=2.1.1.320 {ECO:0000269|PubMed:21081503, ECO:0000269|PubMed:23071334}; AltName: Full=72 kDa ICln-binding protein; AltName: Full=Histone-arginine N-methyltransferase PRMT5; AltName: Full=Jak-binding protein 1; AltName: Full=Shk1 kinase-binding protein 1 homolog; Short=SKB1 homolog; Short=SKB1Hs; Contains: RecName: Full=Protein arginine N-methyltransferase 5, N-terminally processed;+++[B4DV00_HUMAN|Unreviewed]RecName: Full=Protein arginine N-methyltransferase 5 {ECO:0000256|PIRNR:PIRNR015894}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR015894};+++[C9JSX3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000409482}; Flags: Fragment;+++[G3V2F5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450633};+++[G3V2L6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450737}; Flags: Fragment;+++[G3V2X6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450919}; Flags: Fragment;+++[G3V3A3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451127};+++[G3V507_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452102};+++[G3V580_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452218}; Flags: Fragment;+++[G3V5L5_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452411}; Flags: Fragment;+++[G3V5T6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452509}; Flags: Fragment;+++[H0YJ77_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000450956}; Flags: Fragment;+++[H0YJD3_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000451245}; Flags: Fragment;+++[H0YJX6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452409}; Flags: Fragment;+++[H0YJY6_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000452501}; Flags: Fragment;+++[H7BZ44_HUMAN|Unreviewed]SubName: Full=Protein arginine N-methyltransferase 5 {ECO:0000313|Ensembl:ENSP00000387663}; Flags: Fragment;"]
[10420,"'TESK2'",13,15,14,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0000166///nucleotide binding","GO:0030036///actin cytoskeleton organization+++GO:0048041///focal adhesion assembly+++GO:0016310///phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis","IPR008266///Tyrosine-protein kinase, active site+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site","[TESK2_HUMAN|Reviewed]RecName: Full=Dual specificity testis-specific protein kinase 2; EC=2.7.12.1; AltName: Full=Testicular protein kinase 2;+++[B4DFN2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58133, highly similar to Dual specificity testis-specific protein kinase 2 {ECO:0000313|EMBL:BAG57493.1};+++[D3DPZ7_HUMAN|Unreviewed]SubName: Full=Testis-specific kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAX06988.1};"]
[10421,"'CD2BP2'",862,775,818.5,"03015///mRNA surveillance pathway",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005682///U5 snRNP+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0010923///negative regulation of phosphatase activity+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0006397///mRNA processing","IPR003169///GYF domain+++IPR035445///GYF-like domain superfamily+++IPR039905///CD2 antigen cytoplasmic tail-binding protein 2/Lin1","[CD2B2_HUMAN|Reviewed]RecName: Full=CD2 antigen cytoplasmic tail-binding protein 2; Short=CD2 cytoplasmic domain-binding protein 2; Short=CD2 tail-binding protein 2; AltName: Full=U5 snRNP 52K protein; Short=U5-52K;+++[A0A024QZC1_HUMAN|Unreviewed]SubName: Full=CD2 antigen (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW52261.1}; SubName: Full=CD2 binding protein 2 isoform 1 {ECO:0000313|EMBL:ALQ33976.1};+++[A0A0S2Z5J7_HUMAN|Unreviewed]SubName: Full=CD2 binding protein 2 isoform 2 {ECO:0000313|EMBL:ALQ33977.1}; Flags: Fragment;"]
[10422,"'UBAC1'",539,381,460,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0016567///protein ubiquitination","IPR015940///Ubiquitin-associated domain+++IPR029071///Ubiquitin-like domain superfamily+++IPR006636///Heat shock chaperonin-binding+++IPR009060///UBA-like superfamily","[UBAC1_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated domain-containing protein 1; Short=UBA domain-containing protein 1; AltName: Full=E3 ubiquitin-protein ligase subunit KPC2; AltName: Full=Glialblastoma cell differentiation-related protein 1; AltName: Full=Kip1 ubiquitination-promoting complex protein 2;+++[A0A024R8I2_HUMAN|Unreviewed]SubName: Full=Ubiquitin associated domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW88190.1};+++[A0A140VK64_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 64 {ECO:0000313|EMBL:AEE61201.1};"]
[10423,"'CDIPT'",2127,2017,2072,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00564///Glycerophospholipid metabolism+++00562///Inositol phosphate metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase   CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus","GO:0019992///diacylglycerol binding+++GO:0043178///alcohol binding+++GO:0030246///carbohydrate binding+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046341///CDP-diacylglycerol metabolic process","IPR000462///CDP-alcohol phosphatidyltransferase+++IPR014387///CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote","[CDIPT_HUMAN|Reviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase; EC=2.7.8.11; AltName: Full=Phosphatidylinositol synthase; Short=PI synthase; Short=PtdIns synthase;+++[A8K3L7_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KSW0_HUMAN|Unreviewed]RecName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000256|PIRNR:PIRNR000848}; EC=2.7.8.11 {ECO:0000256|PIRNR:PIRNR000848};+++[B3KY94_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000455042}; SubName: Full=cDNA FLJ16129 fis, clone BRACE2039823, highly similar to CDP-diacylglycerol--inositol3-phosphatidyltransferase {ECO:0000313|EMBL:BAG54756.1};+++[H3BTJ7_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457207};+++[H3BUR9_HUMAN|Unreviewed]SubName: Full=CDP-diacylglycerol--inositol 3-phosphatidyltransferase {ECO:0000313|Ensembl:ENSP00000457766};"]
[10424,"'PGRMC2'",1876,2002,1939,{"$nulls":4},"GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0005496///steroid binding+++GO:0003707///steroid hormone receptor activity","GO:0043401///steroid hormone mediated signaling pathway","IPR001199///Cytochrome b5-like heme/steroid binding domain+++IPR036400///Cytochrome b5-like heme/steroid binding domain superfamily","[PGRC2_HUMAN|Reviewed]RecName: Full=Membrane-associated progesterone receptor component 2; AltName: Full=Progesterone membrane-binding protein; AltName: Full=Steroid receptor protein DG6;+++[D3DNX8_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475242}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_a {ECO:0000313|EMBL:EAX05179.1};+++[U3KQ70_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000475603}; Flags: Fragment;+++[U3KQM0_HUMAN|Unreviewed]SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|Ensembl:ENSP00000476010}; SubName: Full=Progesterone receptor membrane component 2, isoform CRA_c {ECO:0000313|EMBL:EAX05182.1};"]
[10425,"'ARIH2'",714.61,715.38,714.995,{"$nulls":4},"GO:0005634///nucleus+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0016740///transferase activity","GO:0016567///protein ubiquitination+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0007275///multicellular organism development+++GO:0070936///protein K48-linked ubiquitination+++GO:0048588///developmental cell growth+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination","IPR001841///Zinc finger, RING-type+++IPR017907///Zinc finger, RING-type, conserved site+++IPR002867///IBR domain+++IPR031126///E3 ubiquitin-protein ligase ARIH2+++IPR031127///E3 ubiquitin ligase RBR family+++IPR013083///Zinc finger, RING/FYVE/PHD-type","[ARI2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase ARIH2; Short=ARI-2; Short=Protein ariadne-2 homolog; EC=2.3.2.31 {ECO:0000269|PubMed:16118314, ECO:0000269|PubMed:17646546, ECO:0000269|PubMed:19340006}; AltName: Full=RING-type E3 ubiquitin transferase ARIH2 {ECO:0000305}; AltName: Full=Triad1 protein {ECO:0000303|PubMed:10422847};+++[C9JAU2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000406063}; Flags: Fragment;+++[C9JBC5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000397225}; Flags: Fragment;+++[C9JCL4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000404838}; Flags: Fragment;+++[C9JZ71_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000399788}; Flags: Fragment;+++[F8WCS4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase ARIH2 {ECO:0000313|Ensembl:ENSP00000403845};+++[Q53ET9_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;+++[Q6IBL8_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};"]
[10426,"'TUBGCP3'",150,208,179,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005816///spindle pole body+++GO:0000923///equatorial microtubule organizing center+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000930///gamma-tubulin complex+++GO:0008275///gamma-tubulin small complex+++GO:0005827///polar microtubule+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005814///centriole+++GO:0005874///microtubule+++GO:0016020///membrane","GO:0005198///structural molecule activity+++GO:0051011///microtubule minus-end binding+++GO:0005515///protein binding+++GO:0043015///gamma-tubulin binding+++GO:0005200///structural constituent of cytoskeleton","GO:0007020///microtubule nucleation+++GO:0051321///meiotic cell cycle+++GO:0090307///mitotic spindle assembly+++GO:0000226///microtubule cytoskeleton organization+++GO:0007338///single fertilization+++GO:0051415///microtubule nucleation by interphase microtubule organizing center+++GO:0031122///cytoplasmic microtubule organization","IPR007259///Gamma-tubulin complex component protein","[GCP3_HUMAN|Reviewed]RecName: Full=Gamma-tubulin complex component 3; Short=GCP-3; Short=hGCP3; AltName: Full=Gamma-ring complex protein 104 kDa; Short=h104p; Short=hGrip104; AltName: Full=Spindle pole body protein Spc98 homolog; Short=hSpc98;+++[A0A087WU06_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};+++[A0A087WZV5_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX56_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[A0A0J9YX63_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050}; Flags: Fragment;+++[B4DYP7_HUMAN|Unreviewed]RecName: Full=Gamma-tubulin complex component {ECO:0000256|RuleBase:RU363050};"]
[10427,"'SEC24B'",436,741,588.5,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031410///cytoplasmic vesicle+++GO:0000139///Golgi membrane+++GO:0030127///COPII vesicle coat+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:1901301///regulation of cargo loading into COPII-coated vesicle+++GO:0001843///neural tube closure+++GO:0015031///protein transport+++GO:0072358///cardiovascular system development+++GO:0002093///auditory receptor cell morphogenesis+++GO:0060982///coronary artery morphogenesis+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0060425///lung morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0006886///intracellular protein transport+++GO:0061156///pulmonary artery morphogenesis+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0021747///cochlear nucleus development+++GO:0035909///aorta morphogenesis+++GO:0016192///vesicle-mediated transport+++GO:0090178///regulation of establishment of planar polarity involved in neural tube closure+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060463///lung lobe morphogenesis","IPR012990///Sec23/Sec24 beta-sandwich+++IPR007123///Gelsolin-like domain+++IPR036174///Zinc finger, Sec23/Sec24-type superfamily+++IPR006895///Zinc finger, Sec23/Sec24-type+++IPR006896///Sec23/Sec24, trunk domain+++IPR036175///Sec23/Sec24 helical domain superfamily+++IPR036465///von Willebrand factor A-like domain superfamily+++IPR036180///Gelsolin-like domain superfamily+++IPR006900///Sec23/Sec24, helical domain+++IPR029006///ADF-H/Gelsolin-like domain superfamily","[SC24B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24B {ECO:0000305}; AltName: Full=SEC24-related protein B;+++[B4DTM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61391, highly similar to Protein transport protein Sec24B {ECO:0000313|EMBL:BAG62038.1};"]
[10428,"'CFDP1'",319,265,292,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0005575///cellular_component+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore","GO:0003674///molecular_function","GO:0007275///multicellular organism development+++GO:2000270///negative regulation of fibroblast apoptotic process+++GO:0008150///biological_process+++GO:0008360///regulation of cell shape+++GO:0007155///cell adhesion+++GO:0042127///regulation of cell proliferation","IPR011421///BCNT-C domain+++IPR027124///SWR1-complex protein 5/Craniofacial development protein","[CFDP1_HUMAN|Reviewed]RecName: Full=Craniofacial development protein 1; AltName: Full=Bucentaur;+++[A0A087WXQ2_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000481200}; Flags: Fragment;+++[A0A0H5APX3_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91204.1};+++[A0A0H5AUJ9_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91203.1};+++[A0A0H5B9V7_HUMAN|Unreviewed]SubName: Full=Bucentaur {ECO:0000313|EMBL:BAR91205.1};+++[H3BQ17_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000455564}; Flags: Fragment;+++[J3KT89_HUMAN|Unreviewed]SubName: Full=Craniofacial development protein 1 {ECO:0000313|Ensembl:ENSP00000462862}; Flags: Fragment;"]
[10430,"'TMEM147'",1669,1241,1455,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0032991///protein-containing complex","GO:0005515///protein binding",null,"IPR019164///Transmembrane protein 147","[TM147_HUMAN|Reviewed]RecName: Full=Transmembrane protein 147; AltName: Full=Protein NIFIE 14;+++[A8MU21_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000376041};+++[K7ELX3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 147 {ECO:0000313|Ensembl:ENSP00000466262};"]
[10432,"'RBM14'",780.66,841.43,811.045,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016607///nuclear speck+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0003676///nucleic acid binding+++GO:0030674///protein binding, bridging+++GO:0003723///RNA binding+++GO:0003712///transcription coregulator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006260///DNA replication+++GO:0002218///activation of innate immune response+++GO:0006281///DNA repair+++GO:0045087///innate immune response+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0006310///DNA recombination+++GO:0016575///histone deacetylation+++GO:0098534///centriole assembly+++GO:0046600///negative regulation of centriole replication+++GO:0002376///immune system process+++GO:0009725///response to hormone+++GO:0042921///glucocorticoid receptor signaling pathway","IPR034507///RBM14, RNA recognition motif 2+++IPR000504///RNA recognition motif domain+++IPR034506///RBM14, RNA recognition motif 1+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR035979///RNA-binding domain superfamily","[RBM14_HUMAN|Reviewed]RecName: Full=RNA-binding protein 14; AltName: Full=Paraspeckle protein 2; Short=PSP2; AltName: Full=RNA-binding motif protein 14; AltName: Full=RRM-containing coactivator activator/modulator; AltName: Full=Synaptotagmin-interacting protein; Short=SYT-interacting protein;+++[A0A0S2Z4Z0_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 1 {ECO:0000313|EMBL:ALQ33978.1}; Flags: Fragment;+++[A0A0S2Z567_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 2 {ECO:0000313|EMBL:ALQ33979.1};+++[A0A0S2Z5V2_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 14 isoform 3 {ECO:0000313|EMBL:ALQ33980.1};+++[B8ZZ74_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000386518};+++[F8WDX3_HUMAN|Unreviewed]SubName: Full=RNA-binding protein 14 {ECO:0000313|Ensembl:ENSP00000414650};"]
[10434,"'LYPLA1'",403,476,439.5,"05231///Choline metabolism in cancer+++00564///Glycerophospholipid metabolism",null,null,"R02746///1-Acyl-sn-glycero-3-phosphocholine acylhydrolase   1-Acyl-sn-glycero-3-phosphocholine + H2O <=> sn-Glycero-3-phosphocholine + Fatty acid+++R03416///1-Acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase   1-Acyl-sn-glycero-3-phosphoethanolamine + H2O <=> Fatty acid + sn-Glycero-3-phosphoethanolamine","GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0004622///lysophospholipase activity+++GO:0016787///hydrolase activity+++GO:0016298///lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0005515///protein binding+++GO:0008474///palmitoyl-(protein) hydrolase activity","GO:0042997///negative regulation of Golgi to plasma membrane protein transport+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0006631///fatty acid metabolic process+++GO:0002084///protein depalmitoylation+++GO:0006629///lipid metabolic process","IPR029058///Alpha/Beta hydrolase fold+++IPR003140///Phospholipase/carboxylesterase/thioesterase","[LYPA1_HUMAN|Reviewed]RecName: Full=Acyl-protein thioesterase 1; Short=APT-1; Short=hAPT1; EC=3.1.2.-; AltName: Full=Lysophospholipase 1; AltName: Full=Lysophospholipase I; Short=LPL-I; Short=LysoPLA I;+++[A0A087X1K9_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000484280};+++[B4DP64_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000482430}; SubName: Full=cDNA FLJ52008, highly similar to Acyl-protein thioesterase 1 {ECO:0000313|EMBL:BAG60476.1};+++[E5RFT6_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000427967};+++[E5RGR0_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428729}; Flags: Fragment;+++[E5RI35_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000430791}; Flags: Fragment;+++[E5RJ48_HUMAN|Unreviewed]SubName: Full=Acyl-protein thioesterase 1 {ECO:0000313|Ensembl:ENSP00000428306}; Flags: Fragment;+++[Q6IAQ1_HUMAN|Unreviewed]SubName: Full=LYPLA1 protein {ECO:0000313|EMBL:CAG33384.1}; SubName: Full=Lysophospholipase I, isoform CRA_a {ECO:0000313|EMBL:EAW86742.1}; SubName: Full=cDNA FLJ78542, highly similar to Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAF82089.1}; SubName: Full=cDNA, FLJ94339, Homo sapiens lysophospholipase I (LYPLA1), mRNA {ECO:0000313|EMBL:BAG36480.1};"]
[10435,"'CDC42EP2'",631,512,571.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0005886///plasma membrane+++GO:0045335///phagocytic vesicle+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017049///GTP-Rho binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0001515///opioid peptide activity","GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity+++GO:0007266///Rho protein signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0008360///regulation of cell shape+++GO:0010469///regulation of signaling receptor activity+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007015///actin filament organization+++GO:0031334///positive regulation of protein complex assembly+++GO:0031274///positive regulation of pseudopodium assembly","IPR000095///CRIB domain+++IPR017363///Cdc42 effector protein 2+++IPR029273///Cdc42 effector","[BORG1_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 2; AltName: Full=Binder of Rho GTPases 1;"]
[10436,"'EMG1'",169,159,164,"03008///Ribosome biogenesis in eukaryotes","H00616///Bowen-Conradi syndrome (BCS)",null,"R04480///Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase Phosphatidylethanolamine + CoA <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Acyl-CoA+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R09035///acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoserine <=> CoA + Phosphatidylserine","GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0070037///rRNA (pseudouridine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0019843///rRNA binding+++GO:0016740///transferase activity","GO:0042274///ribosomal small subunit biogenesis+++GO:0042254///ribosome biogenesis+++GO:0001824///blastocyst development+++GO:0017126///nucleologenesis+++GO:0032259///methylation+++GO:0070475///rRNA base methylation+++GO:0006364///rRNA processing","IPR029026///tRNA (guanine-N1-)-methyltransferase, N-terminal+++IPR029028///Alpha/beta knot methyltransferases+++IPR005304///Ribosomal biogenesis, methyltransferase, EMG1/NEP1","[NEP1_HUMAN|Reviewed]RecName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000305|PubMed:20047967}; EC=2.1.1.- {ECO:0000269|PubMed:20047967}; AltName: Full=18S rRNA (pseudouridine(1248)-N1)-methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=18S rRNA Psi1248 methyltransferase {ECO:0000303|PubMed:20047967}; AltName: Full=Nucleolar protein EMG1 homolog {ECO:0000250|UniProtKB:Q06287}; AltName: Full=Protein C2f {ECO:0000303|PubMed:9074930}; AltName: Full=Ribosome biogenesis protein NEP1 {ECO:0000303|PubMed:20047967};+++[A0A087WVM7_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000479546}; Flags: Fragment;+++[A0A087WWQ2_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000480420}; Flags: Fragment;+++[A0A0U3B3H7_HUMAN|Unreviewed]SubName: Full=EMG1 N1-specific pseudouridine methyl transferase {ECO:0000313|EMBL:ALT07792.1}; Flags: Fragment;+++[B4DP65_HUMAN|Unreviewed]SubName: Full=EMG1 nucleolar protein homolog (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW88694.1}; SubName: Full=cDNA FLJ56921, highly similar to Probable ribosome biogenesis protein NEP1 {ECO:0000313|EMBL:BAG60477.1};+++[V9GYP5_HUMAN|Unreviewed]SubName: Full=Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000313|Ensembl:ENSP00000476966}; Flags: Fragment;"]
[10437,"'IFI30'",402,288,345,"04612///Antigen processing and presentation",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0030054///cell junction+++GO:0043202///lysosomal lumen+++GO:0005764///lysosome+++GO:0005576///extracellular region+++GO:0005829///cytosol","GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0016667///oxidoreductase activity, acting on a sulfur group of donors","GO:0055114///oxidation-reduction process+++GO:0002376///immune system process+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I","IPR004911///Gamma interferon inducible lysosomal thiol reductase GILT","[GILT_HUMAN|Reviewed]RecName: Full=Gamma-interferon-inducible lysosomal thiol reductase; EC=1.8.-.- {ECO:0000269|PubMed:10639150, ECO:0000269|PubMed:10852914}; AltName: Full=Gamma-interferon-inducible protein IP-30; AltName: Full=Legumaturain; Flags: Precursor;+++[A0A024R7N7_HUMAN|Unreviewed]SubName: Full=Interferon, gamma-inducible protein 30, isoform CRA_b {ECO:0000313|EMBL:EAW84665.1};+++[M0QZG3_HUMAN|Unreviewed]SubName: Full=Gamma-interferon-inducible lysosomal thiol reductase {ECO:0000313|Ensembl:ENSP00000470527}; Flags: Fragment;+++[Q96P99_HUMAN|Unreviewed]SubName: Full=Interferon gamma-inducible protein 30 {ECO:0000313|EMBL:AAL02170.1}; Flags: Fragment;"]
[10438,"'C1D'",154,161,157.5,"03018///RNA degradation",{"$nulls":3},"GO:0017053///transcriptional repressor complex+++GO:0005769///early endosome+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030425///dendrite+++GO:0043025///neuronal cell body+++GO:0098797///plasma membrane protein complex+++GO:0005886///plasma membrane+++GO:0030666///endocytic vesicle membrane+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0000176///nuclear exosome (RNase complex)+++GO:0005905///clathrin-coated pit+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0005768///endosome+++GO:0030136///clathrin-coated vesicle+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex","GO:0044877///protein-containing complex binding+++GO:0003677///DNA binding+++GO:0016964///alpha-2 macroglobulin receptor activity+++GO:0002020///protease binding+++GO:0042954///lipoprotein transporter activity+++GO:0032050///clathrin heavy chain binding+++GO:0038023///signaling receptor activity+++GO:0003714///transcription corepressor activity+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0030226///apolipoprotein receptor activity+++GO:0005509///calcium ion binding+++GO:0070325///lipoprotein particle receptor binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005044///scavenger receptor activity+++GO:0001540///amyloid-beta binding+++GO:0005515///protein binding+++GO:0016922///nuclear receptor binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0034185///apolipoprotein binding","GO:0042157///lipoprotein metabolic process+++GO:0006915///apoptotic process+++GO:0006364///rRNA processing+++GO:0032092///positive regulation of protein binding+++GO:0051222///positive regulation of protein transport+++GO:0008283///cell proliferation+++GO:0032374///regulation of cholesterol transport+++GO:0010942///positive regulation of cell death+++GO:1900223///positive regulation of amyloid-beta clearance+++GO:0042953///lipoprotein transport+++GO:0006897///endocytosis+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:2000587///negative regulation of platelet-derived growth factor receptor-beta signaling pathway+++GO:0010875///positive regulation of cholesterol efflux+++GO:0002265///astrocyte activation involved in immune response+++GO:0006629///lipid metabolic process+++GO:0000460///maturation of 5.8S rRNA+++GO:0035909///aorta morphogenesis+++GO:0043277///apoptotic cell clearance+++GO:0045732///positive regulation of protein catabolic process+++GO:0051246///regulation of protein metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010977///negative regulation of neuron projection development+++GO:0031623///receptor internalization+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:1905167///positive regulation of lysosomal protein catabolic process+++GO:0032429///regulation of phospholipase A2 activity+++GO:1904646///cellular response to amyloid-beta+++GO:0006898///receptor-mediated endocytosis+++GO:0001523///retinoid metabolic process+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0021987///cerebral cortex development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0045056///transcytosis+++GO:0097242///amyloid-beta clearance+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0006909///phagocytosis+++GO:0032370///positive regulation of lipid transport+++GO:0007275///multicellular organism development+++GO:0007568///aging+++GO:0045807///positive regulation of endocytosis","IPR007146///Sas10/Utp3/C1D+++IPR011082///Exosome-associated factor Rrp47/DNA strand repair C1D","[C1D_HUMAN|Reviewed]RecName: Full=Nuclear nucleic acid-binding protein C1D; Short=hC1D;+++[H0YJ88_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451012}; Flags: Fragment;+++[H0YJI8_HUMAN|Unreviewed]SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451622}; Flags: Fragment;+++[J3KPZ4_HUMAN|Unreviewed]SubName: Full=Nuclear nucleic acid-binding protein C1D {ECO:0000313|Ensembl:ENSP00000384304};+++[L0R6J6_HUMAN|Unreviewed]SubName: Full=Alternative protein LRP1 {ECO:0000313|EMBL:CCO13765.1};+++[Q6PJ72_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH21204.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451737};+++[Q7Z7K9_HUMAN|Unreviewed]SubName: Full=LRP1 protein {ECO:0000313|EMBL:AAH52593.1}; SubName: Full=Prolow-density lipoprotein receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000451449};"]
[10439,"'OLFM1'",308,302,305,{"$nulls":4},"GO:0045202///synapse+++GO:0043204///perikaryon+++GO:0005615///extracellular space+++GO:0042995///cell projection+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0030054///cell junction+++GO:0030424///axon+++GO:0044295///axonal growth cone+++GO:0005623///cell+++GO:0005576///extracellular region","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0030516///regulation of axon extension+++GO:0023041///neuronal signal transduction+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0003190///atrioventricular valve formation+++GO:0010628///positive regulation of gene expression+++GO:0010629///negative regulation of gene expression","IPR011044///Quinoprotein amine dehydrogenase, beta chain-like+++IPR022082///Noelin domain+++IPR003112///Olfactomedin-like domain+++IPR031217///Noelin","[NOE1_HUMAN|Reviewed]RecName: Full=Noelin; AltName: Full=Neuronal olfactomedin-related ER localized protein; AltName: Full=Olfactomedin-1; Flags: Precursor;+++[F5GZQ2_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000444296}; Flags: Fragment;+++[F5H810_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000443806}; Flags: Fragment;+++[F8W870_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000340318}; Flags: Fragment;+++[H0YFB9_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000437906}; Flags: Fragment;+++[Q5VZL8_HUMAN|Unreviewed]SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360866};+++[Q6IMJ6_HUMAN|Unreviewed]SubName: Full=NOELIN1_V5 {ECO:0000313|EMBL:DAA01549.1}; SubName: Full=Noelin {ECO:0000313|Ensembl:ENSP00000360864};+++[Q6IMJ7_HUMAN|Unreviewed]SubName: Full=NOELIN1_V4 {ECO:0000313|EMBL:DAA01548.1}; SubName: Full=Olfactomedin 1, isoform CRA_d {ECO:0000313|EMBL:EAW88145.1};+++[Q6IMJ8_HUMAN|Unreviewed]SubName: Full=NOELIN1_V1 {ECO:0000313|EMBL:DAA01545.1}; SubName: Full=Olfactomedin 1, isoform CRA_c {ECO:0000313|EMBL:EAW88144.1};+++[Q96BL8_HUMAN|Unreviewed]SubName: Full=OLFM1 protein {ECO:0000313|EMBL:AAH15437.2}; Flags: Fragment;+++[Q9BWJ9_HUMAN|Unreviewed]SubName: Full=Olfactomedin 1 {ECO:0000313|EMBL:AAH00189.1}; SubName: Full=Olfactomedin 1, isoform CRA_b {ECO:0000313|EMBL:EAW88143.1};"]
[10440,"'TIMM17A'",494,422,458,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex","GO:0008320///protein transmembrane transporter activity+++GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity","GO:0010954///positive regulation of protein processing+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0071806///protein transmembrane transport+++GO:0006886///intracellular protein transport+++GO:0006626///protein targeting to mitochondrion","IPR005678///Mitochondrial inner membrane translocase complex, subunit Tim17","[TI17A_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit Tim17-A; AltName: Full=Inner membrane preprotein translocase Tim17a;+++[A0A024R9A5_HUMAN|Unreviewed]SubName: Full=Translocase of inner mitochondrial membrane 17 homolog A (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW91385.1};+++[A0PJ74_HUMAN|Unreviewed]SubName: Full=TIMM17A protein {ECO:0000313|EMBL:AAH16817.1}; Flags: Fragment;+++[Q7RU05_HUMAN|Unreviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM17 {ECO:0000256|RuleBase:RU364008};"]
[10443,"'N4BP2L2'",287,287,287,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0017053///transcriptional repressor complex","GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0003714///transcription corepressor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1902037///negative regulation of hematopoietic stem cell differentiation+++GO:1902035///positive regulation of hematopoietic stem cell proliferation","IPR026568///NEDD4-binding protein 2-like 2+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[N42L2_HUMAN|Reviewed]RecName: Full=NEDD4-binding protein 2-like 2; AltName: Full=Phosphonoformate immuno-associated protein 5;+++[A0A024RDV2_HUMAN|Unreviewed]SubName: Full=HCG32190, isoform CRA_b {ECO:0000313|EMBL:EAX08515.1};+++[B4DPY1_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000350104}; SubName: Full=cDNA FLJ55497 {ECO:0000313|EMBL:BAG60743.1};+++[D6R968_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 2-like 2 {ECO:0000313|Ensembl:ENSP00000423362}; Flags: Fragment;+++[Q96KV2_HUMAN|Unreviewed]SubName: Full=92M18.3 (Novel protein) {ECO:0000313|EMBL:CAC94790.1};+++[Q9Y3H6_HUMAN|Unreviewed]SubName: Full=HCG33128, isoform CRA_a {ECO:0000313|EMBL:EAX08509.1};"]
[10444,"'ZER1'",2567,2671,2619,{"$nulls":4},"GO:0031462///Cul2-RING ubiquitin ligase complex","GO:0004842///ubiquitin-protein transferase activity","GO:0051438///regulation of ubiquitin-protein transferase activity+++GO:0016567///protein ubiquitination","IPR000225///Armadillo+++IPR032675///Leucine-rich repeat domain superfamily+++IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical","[ZER1_HUMAN|Reviewed]RecName: Full=Protein zer-1 homolog; AltName: Full=Hzyg; AltName: Full=Zyg-11 homolog B-like protein; AltName: Full=Zyg11b-like protein;+++[A0A024R8B0_HUMAN|Unreviewed]SubName: Full=Zyg-11 homolog B (C. elegans)-like, isoform CRA_b {ECO:0000313|EMBL:EAW87831.1};+++[Q05BR7_HUMAN|Unreviewed]SubName: Full=ZER1 protein {ECO:0000313|EMBL:AAH33884.1}; Flags: Fragment;+++[X6RC68_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000389271}; Flags: Fragment;+++[X6RD87_HUMAN|Unreviewed]SubName: Full=Protein zer-1 homolog {ECO:0000313|Ensembl:ENSP00000393051}; Flags: Fragment;"]
[10445,"'MCRS1'",856,683,769.5,"05168///Herpes simplex infection",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0044545///NSL complex+++GO:0043204///perikaryon+++GO:0030425///dendrite+++GO:0000123///histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0031011///Ino80 complex+++GO:0005634///nucleus+++GO:0071339///MLL1 complex+++GO:0005730///nucleolus+++GO:0005844///polysome","GO:0046972///histone acetyltransferase activity (H4-K16 specific)+++GO:0034046///poly(G) binding+++GO:0043996///histone acetyltransferase activity (H4-K8 specific)+++GO:0010521///telomerase inhibitor activity+++GO:0043995///histone acetyltransferase activity (H4-K5 specific)+++GO:0008266///poly(U) RNA binding+++GO:0005515///protein binding+++GO:0002151///G-quadruplex RNA binding","GO:0006310///DNA recombination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006464///cellular protein modification process+++GO:0043982///histone H4-K8 acetylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043981///histone H4-K5 acetylation+++GO:0051974///negative regulation of telomerase activity+++GO:0016579///protein deubiquitination+++GO:0043984///histone H4-K16 acetylation+++GO:0006281///DNA repair+++GO:1904751///positive regulation of protein localization to nucleolus+++GO:0006325///chromatin organization+++GO:1904357///negative regulation of telomere maintenance via telomere lengthening","IPR037912///Microspherule protein 1+++IPR008984///SMAD/FHA domain superfamily+++IPR000253///Forkhead-associated (FHA) domain+++IPR025999///Microspherule protein, N-terminal domain","[MCRS1_HUMAN|Reviewed]RecName: Full=Microspherule protein 1; AltName: Full=58 kDa microspherule protein; AltName: Full=Cell cycle-regulated factor p78; AltName: Full=INO80 complex subunit J; AltName: Full=MCRS2;+++[A0A024R134_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1, isoform CRA_d {ECO:0000313|EMBL:EAW58079.1};+++[F8VP44_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000450352}; Flags: Fragment;+++[F8VVA6_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000449343}; Flags: Fragment;+++[F8VZC2_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447739};+++[F8W0I9_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447592}; Flags: Fragment;+++[F8W126_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000447514}; Flags: Fragment;+++[H0YI67_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448700}; Flags: Fragment;+++[H0YIA0_HUMAN|Unreviewed]SubName: Full=Microspherule protein 1 {ECO:0000313|Ensembl:ENSP00000448947}; Flags: Fragment;+++[L8E8H6_HUMAN|Unreviewed]SubName: Full=Alternative protein MCRS1 {ECO:0000313|EMBL:CCQ43031.1};"]
[10446,"'LRRN2'",1150,1358,1254,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005615///extracellular space","GO:0038023///signaling receptor activity","GO:0007165///signal transduction+++GO:0007155///cell adhesion","IPR003598///Immunoglobulin subtype 2+++IPR001611///Leucine-rich repeat+++IPR013783///Immunoglobulin-like fold+++IPR013098///Immunoglobulin I-set+++IPR032675///Leucine-rich repeat domain superfamily+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR007110///Immunoglobulin-like domain+++IPR003599///Immunoglobulin subtype+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003591///Leucine-rich repeat, typical subtype","[LRRN2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat neuronal protein 2; AltName: Full=Glioma amplified on chromosome 1 protein; AltName: Full=Leucine-rich repeat neuronal protein 5; Flags: Precursor;+++[A0A024R993_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat neuronal 5, isoform CRA_a {ECO:0000313|EMBL:EAW91521.1};"]
[10447,"'FAM3C'",579,595,587,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031089///platelet dense granule lumen+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle","GO:0005125///cytokine activity+++GO:0005515///protein binding","GO:0010469///regulation of signaling receptor activity+++GO:0008150///biological_process+++GO:0045721///negative regulation of gluconeogenesis+++GO:0007275///multicellular organism development+++GO:0002576///platelet degranulation","IPR039219///Protein FAM3C+++IPR039475///FAM3C (ILEI) domain+++IPR039220///FAM3 family+++IPR039477///ILEI/PANDER domain","[FAM3C_HUMAN|Reviewed]RecName: Full=Protein FAM3C; AltName: Full=Interleukin-like EMT inducer; Flags: Precursor;+++[C9JMN4_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000408636}; Flags: Fragment;+++[C9JP35_HUMAN|Unreviewed]SubName: Full=Protein FAM3C {ECO:0000313|Ensembl:ENSP00000414940}; Flags: Fragment;"]
[10449,"'ACAA2'",666,524,595,"01212///Fatty acid metabolism+++01100///Metabolic pathways+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++00280///Valine, leucine and isoleucine degradation+++01130///Biosynthesis of antibiotics+++00062///Fatty acid elongation",null,"M00087///beta-Oxidation+++M00085///Fatty acid biosynthesis, elongation, mitochondria","R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase   Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase   Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase   Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00391///Acyl-CoA:acetyl-CoA C-acyltransferase   Acyl-CoA + Acetyl-CoA <=> CoA + 3-Oxoacyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase   Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase   Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase   Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA   Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA","GO:0005759///mitochondrial matrix+++GO:0016459///myosin complex+++GO:0005739///mitochondrion","GO:0003824///catalytic activity+++GO:0000166///nucleotide binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0003774///motor activity+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding","GO:0006629///lipid metabolic process+++GO:1902109///negative regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0006695///cholesterol biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0071456///cellular response to hypoxia+++GO:0006635///fatty acid beta-oxidation+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","IPR020610///Thiolase, active site+++IPR020617///Thiolase, C-terminal+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001609///Myosin head, motor domain+++IPR020613///Thiolase, conserved site+++IPR020616///Thiolase, N-terminal+++IPR002710///Dilute domain+++IPR020615///Thiolase, acyl-enzyme intermediate active site+++IPR016039///Thiolase-like+++IPR037990///Myosin 5b, cargo-binding domain+++IPR002155///Thiolase+++IPR036961///Kinesin motor domain superfamily+++IPR000048///IQ motif, EF-hand binding site","[THIM_HUMAN|Reviewed]RecName: Full=3-ketoacyl-CoA thiolase, mitochondrial; EC=2.3.1.16; AltName: Full=Acetyl-CoA acyltransferase; AltName: Full=Beta-ketothiolase; AltName: Full=Mitochondrial 3-oxoacyl-CoA thiolase; AltName: Full=T1;+++[A0A024R269_HUMAN|Unreviewed]SubName: Full=Acetyl-Coenzyme A acyltransferase 2 (Mitochondrial 3-oxoacyl-Coenzyme A thiolase), isoform CRA_d {ECO:0000313|EMBL:EAW62956.1};+++[A0A0B4J2A4_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466015};+++[B3KNP8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30111 fis, clone BNGH42000360, highly similar to 3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|EMBL:BAG51410.1};+++[K7EJ68_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465045}; Flags: Fragment;+++[K7EJB1_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465095}; Flags: Fragment;+++[K7EME0_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000466466};+++[K7ER88_HUMAN|Unreviewed]SubName: Full=3-ketoacyl-CoA thiolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000468157}; Flags: Fragment;"]
[10450,"'PPIE'",369,228,298.5,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP",null,"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000974///Prp19 complex+++GO:0034774///secretory granule lumen+++GO:0071013///catalytic step 2 spliceosome+++GO:0005576///extracellular region+++GO:0005681///spliceosomal complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0051082///unfolded protein binding+++GO:0016853///isomerase activity+++GO:0003676///nucleic acid binding+++GO:0016018///cyclosporin A binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0008143///poly(A) binding","GO:0006457///protein folding+++GO:0043312///neutrophil degranulation+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0045070///positive regulation of viral genome replication+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006397///mRNA processing+++GO:0006355///regulation of transcription, DNA-templated","IPR024936///Cyclophilin-type peptidyl-prolyl cis-trans isomerase+++IPR020892///Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site+++IPR000504///RNA recognition motif domain+++IPR016304///Peptidyl-prolyl cis-trans isomerase E+++IPR034168///Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif+++IPR035979///RNA-binding domain superfamily+++IPR002130///Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain+++IPR029000///Cyclophilin-like domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[PPIE_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase E; Short=PPIase E; EC=5.2.1.8 {ECO:0000269|PubMed:18258190, ECO:0000269|PubMed:20541251, ECO:0000269|PubMed:20677832, ECO:0000269|PubMed:8977107}; AltName: Full=Cyclophilin E; AltName: Full=Cyclophilin-33 {ECO:0000303|PubMed:8977107}; AltName: Full=Rotamase E;+++[B3KSZ1_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PEQ6_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};+++[E9PIB0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000436689}; Flags: Fragment;+++[E9PK21_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000431714};+++[E9PKY5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[E9PMH0_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434989};+++[H0YCV4_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000432396}; Flags: Fragment;+++[H0YE31_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase E {ECO:0000313|Ensembl:ENSP00000434888}; Flags: Fragment;"]
[10451,"'VAV3'",33,72,52.5,"04670///Leukocyte transendothelial migration+++04664///Fc epsilon RI signaling pathway+++04662///B cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04650///Natural killer cell mediated cytotoxicity+++04666///Fc gamma R-mediated phagocytosis+++04062///Chemokine signaling pathway+++04660///T cell receptor signaling pathway+++04024///cAMP signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0005096///GTPase activator activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0030676///Rac guanyl-nucleotide exchange factor activity","GO:0001525///angiogenesis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0050853///B cell receptor signaling pathway+++GO:0030032///lamellipodium assembly+++GO:0030031///cell projection assembly+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0016477///cell migration+++GO:0035023///regulation of Rho protein signal transduction+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0043087///regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0008361///regulation of cell size+++GO:0009967///positive regulation of signal transduction+++GO:0048013///ephrin receptor signaling pathway+++GO:0006906///vesicle fusion+++GO:0042493///response to drug+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030593///neutrophil chemotaxis+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0030168///platelet activation+++GO:0030890///positive regulation of B cell proliferation+++GO:0007229///integrin-mediated signaling pathway+++GO:0045785///positive regulation of cell adhesion","IPR036872///CH domain superfamily+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR001715///Calponin homology domain+++IPR022613///Calmodulin-regulated spectrin-associated protein, CH domain+++IPR003096///Smooth muscle protein/calponin+++IPR001331///Guanine-nucleotide dissociation stimulator, CDC24, conserved site+++IPR036860///SH2 domain superfamily+++IPR001849///Pleckstrin homology domain+++IPR037832///Vav, PH domain+++IPR001452///SH3 domain+++IPR000980///SH2 domain+++IPR011993///PH-like domain superfamily+++IPR035734///VAV3 protein, second SH3 domain+++IPR035881///VAV3, SH2 domain+++IPR000219///Dbl homology (DH) domain+++IPR036028///SH3-like domain superfamily+++IPR035899///Dbl homology (DH) domain superfamily","[VAV3_HUMAN|Reviewed]RecName: Full=Guanine nucleotide exchange factor VAV3; Short=VAV-3;+++[A0A2X0U2Q1_HUMAN|Unreviewed]SubName: Full=VAV3 {ECO:0000313|EMBL:SPT35811.1}; Flags: Fragment;+++[E9PMJ5_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000434944};+++[H0YCG7_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000431544}; Flags: Fragment;+++[H0YDG2_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide exchange factor VAV3 {ECO:0000313|Ensembl:ENSP00000433559}; Flags: Fragment;"]
[10452,"'TOMM40'",1515,1234,1374.5,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0046930///pore complex+++GO:0005741///mitochondrial outer membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0005829///cytosol","GO:0008320///protein transmembrane transporter activity+++GO:0015288///porin activity+++GO:0005515///protein binding","GO:0006626///protein targeting to mitochondrion+++GO:0055085///transmembrane transport+++GO:0030150///protein import into mitochondrial matrix+++GO:0015031///protein transport+++GO:0006811///ion transport","IPR023614///Porin domain superfamily+++IPR037930///Tom40+++IPR027246///Eukaryotic porin/Tom40","[TOM40_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM40 homolog; AltName: Full=Protein Haymaker; AltName: Full=Translocase of outer membrane 40 kDa subunit homolog; AltName: Full=p38.5;+++[K7EJ57_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465032}; Flags: Fragment;+++[K7EKG4_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465608}; Flags: Fragment;+++[K7EKG6_HUMAN|Unreviewed]SubName: Full=Mitochondrial import receptor subunit TOM40 homolog {ECO:0000313|Ensembl:ENSP00000465611}; Flags: Fragment;"]
[10454,"'TAB1'",502,554,528,"05145///Toxoplasmosis+++05169///Epstein-Barr virus infection+++05168///Herpes simplex infection+++05140///Leishmaniasis+++04620///Toll-like receptor signaling pathway+++04010///MAPK signaling pathway+++04064///NF-kappa B signaling pathway+++04621///NOD-like receptor signaling pathway+++04668///TNF signaling pathway+++04380///Osteoclast differentiation",null,"M00686///Toll-like receptor signaling",null,"GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0016607///nuclear speck","GO:0003824///catalytic activity+++GO:0008047///enzyme activator activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0044877///protein-containing complex binding+++GO:0019209///kinase activator activity+++GO:0016301///kinase activity+++GO:0048273///mitogen-activated protein kinase p38 binding+++GO:0005515///protein binding","GO:0030324///lung development+++GO:0043406///positive regulation of MAP kinase activity+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0001701///in utero embryonic development+++GO:0000185///activation of MAPKKK activity+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0035904///aorta development+++GO:0003279///cardiac septum development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0006470///protein dephosphorylation+++GO:0000187///activation of MAPK activity+++GO:0060976///coronary vasculature development+++GO:0016579///protein deubiquitination+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0003007///heart morphogenesis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0007254///JNK cascade","IPR001932///PPM-type phosphatase domain+++IPR036457///PPM-type phosphatase domain superfamily+++IPR015655///Protein phosphatase 2C family","[TAB1_HUMAN|Reviewed]RecName: Full=TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; AltName: Full=Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; AltName: Full=TGF-beta-activated kinase 1-binding protein 1; Short=TAK1-binding protein 1;+++[A8K6K3_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 7 interacting protein 1, isoform CRA_f {ECO:0000313|EMBL:EAW60330.1}; SubName: Full=cDNA FLJ78598, highly similar to Homo sapiens mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (MAP3K7IP1), transcript variant alpha, mRNA {ECO:0000313|EMBL:BAF84357.1}; SubName: Full=cDNA, FLJ92811, Homo sapiens mitogen-activated protein kinase kinase kinase 7interacting protein 1 (MAP3K7IP1), mRNA {ECO:0000313|EMBL:BAG35363.1};"]
[10455,"'ECI2'",252,191,221.5,"04146///Peroxisome+++00071///Fatty acid degradation",null,null,"R04756///cis,cis-3,6-Dodecadienoyl-CoA delta3-cis-delta2-trans-isomerase   cis,cis-3,6-Dodecadienoyl-CoA <=> trans,cis-Lauro-2,6-dienoyl-CoA","GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005782///peroxisomal matrix","GO:0000062///fatty-acyl-CoA binding+++GO:0016863///intramolecular oxidoreductase activity, transposing C=C bonds+++GO:0003824///catalytic activity+++GO:0005102///signaling receptor binding+++GO:0016853///isomerase activity+++GO:0004165///dodecenoyl-CoA delta-isomerase activity","GO:0006625///protein targeting to peroxisome+++GO:0009062///fatty acid catabolic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0006635///fatty acid beta-oxidation","IPR014748///Enoyl-CoA hydratase, C-terminal+++IPR001753///Enoyl-CoA hydratase/isomerase+++IPR000582///Acyl-CoA-binding protein, ACBP+++IPR035984///Acyl-CoA binding protein superfamily+++IPR022408///Acyl-CoA-binding protein, ACBP, conserved site+++IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR029045///ClpP/crotonase-like domain superfamily","[ECI2_HUMAN|Reviewed]RecName: Full=Enoyl-CoA delta isomerase 2, mitochondrial; EC=5.3.3.8; AltName: Full=DRS-1; AltName: Full=Delta(3),delta(2)-enoyl-CoA isomerase; Short=D3,D2-enoyl-CoA isomerase; AltName: Full=Diazepam-binding inhibitor-related protein 1; Short=DBI-related protein 1; AltName: Full=Dodecenoyl-CoA isomerase; AltName: Full=Hepatocellular carcinoma-associated antigen 88; AltName: Full=Peroxisomal 3,2-trans-enoyl-CoA isomerase; Short=pECI; AltName: Full=Renal carcinoma antigen NY-REN-1; Flags: Precursor;+++[A0A024QZU5_HUMAN|Unreviewed]SubName: Full=Peroxisomal D3,D2-enoyl-CoA isomerase, isoform CRA_a {ECO:0000313|EMBL:EAW55162.1};+++[A0A0C4DGA2_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000420309}; SubName: Full=Testicular secretory protein Li 33 {ECO:0000313|EMBL:AEE61170.1};+++[C9JB63_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417459}; Flags: Fragment;+++[F1LLU7_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417803};+++[F8W6J1_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000369463};+++[F8WAW4_HUMAN|Unreviewed]SubName: Full=Enoyl-CoA delta isomerase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000417170};+++[Q6IBN4_HUMAN|Unreviewed]SubName: Full=PECI protein {ECO:0000313|EMBL:CAG33049.1};"]
[10456,"'HAX1'",830,631,730.5,null,"H00100///Neutropenic disorders",null,null,"GO:0005938///cell cortex+++GO:0031410///cytoplasmic vesicle+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005783///endoplasmic reticulum+++GO:0005741///mitochondrial outer membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0000932///P-body+++GO:0016529///sarcoplasmic reticulum+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0030027///lamellipodium","GO:0005515///protein binding+++GO:0047485///protein N-terminus binding+++GO:0019966///interleukin-1 binding","GO:0030854///positive regulation of granulocyte differentiation+++GO:0030833///regulation of actin filament polymerization+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:1903146///regulation of autophagy of mitochondrion+++GO:0042981///regulation of apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0071345///cellular response to cytokine stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling","IPR017248///HS1-associating protein X-1","[HAX1_HUMAN|Reviewed]RecName: Full=HCLS1-associated protein X-1; AltName: Full=HS1-associating protein X-1; Short=HAX-1; AltName: Full=HS1-binding protein 1; Short=HSP1BP-1;+++[A0A0S2Z519_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 5 {ECO:0000313|EMBL:ALQ33983.1};+++[A0A0S2Z565_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 3 {ECO:0000313|EMBL:ALQ33982.1}; Flags: Fragment;+++[A0A0S2Z591_HUMAN|Unreviewed]SubName: Full=HCLS1 associated protein X-1 isoform 1 {ECO:0000313|EMBL:ALQ33981.1}; Flags: Fragment;+++[E9PIQ7_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000433951};+++[Q5VYD6_HUMAN|Unreviewed]SubName: Full=HCLS1-associated protein X-1 {ECO:0000313|Ensembl:ENSP00000394920}; Flags: Fragment;"]
[10457,"'GPNMB'",11033,11711,11372,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0016021///integral component of membrane+++GO:0033162///melanosome membrane+++GO:0005887///integral component of plasma membrane","GO:0005178///integrin binding+++GO:0045545///syndecan binding+++GO:0005179///hormone activity+++GO:0005515///protein binding+++GO:0042056///chemoattractant activity+++GO:0048018///receptor ligand activity+++GO:0008201///heparin binding+++GO:0031710///neuromedin B receptor binding","GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0030282///bone mineralization+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007218///neuropeptide signaling pathway+++GO:0050918///positive chemotaxis+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0050482///arachidonic acid secretion+++GO:0001818///negative regulation of cytokine production+++GO:0045765///regulation of angiogenesis+++GO:0050868///negative regulation of T cell activation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0001934///positive regulation of protein phosphorylation+++GO:0007155///cell adhesion+++GO:0046888///negative regulation of hormone secretion+++GO:0034103///regulation of tissue remodeling+++GO:0008284///positive regulation of cell proliferation+++GO:0010469///regulation of signaling receptor activity+++GO:0042130///negative regulation of T cell proliferation+++GO:0042593///glucose homeostasis+++GO:0046887///positive regulation of hormone secretion+++GO:0008285///negative regulation of cell proliferation+++GO:0001649///osteoblast differentiation+++GO:0030335///positive regulation of cell migration+++GO:1901215///negative regulation of neuron death+++GO:0007267///cell-cell signaling+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007165///signal transduction","IPR000601///PKD domain+++IPR035986///PKD domain superfamily+++IPR022409///PKD/Chitinase domain+++IPR013783///Immunoglobulin-like fold","[GPNMB_HUMAN|Reviewed]RecName: Full=Transmembrane glycoprotein NMB; AltName: Full=Hematopoietic growth factor inducible neurokinin-1 type {ECO:0000303|PubMed:12609765}; Flags: Precursor;+++[A0A024RA55_HUMAN|Unreviewed]SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_b {ECO:0000313|EMBL:EAW93784.1};+++[Q8IXJ5_HUMAN|Unreviewed]SubName: Full=Glycoprotein nmb-like protein {ECO:0000313|EMBL:CAD43718.1};+++[Q96F58_HUMAN|Unreviewed]SubName: Full=GPNMB protein {ECO:0000313|EMBL:AAH11595.1}; SubName: Full=Glycoprotein (Transmembrane) nmb {ECO:0000313|EMBL:AAP35737.1}; SubName: Full=Glycoprotein (Transmembrane) nmb, isoform CRA_a {ECO:0000313|EMBL:EAW93781.1}; SubName: Full=Transmembrane glycoprotein NMB {ECO:0000313|Ensembl:ENSP00000386476};"]
[10458,"'BAIAP2'",2655,2458,2556.5,"04520///Adherens junction+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0099524///postsynaptic cytosol+++GO:0061846///dendritic spine cytoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0043197///dendritic spine+++GO:0043025///neuronal cell body+++GO:0097060///synaptic membrane+++GO:0015629///actin cytoskeleton+++GO:0044306///neuron projection terminus+++GO:0042995///cell projection+++GO:0043198///dendritic shaft+++GO:0030175///filopodium+++GO:0001726///ruffle+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098978///glutamatergic synapse+++GO:0005794///Golgi apparatus+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0098793///presynapse+++GO:0099092///postsynaptic density, intracellular component+++GO:0099523///presynaptic cytosol+++GO:0061845///neuron projection branch point+++GO:0005791///rough endoplasmic reticulum+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0060076///excitatory synapse+++GO:0098794///postsynapse+++GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0014069///postsynaptic density","GO:0001221///transcription cofactor binding+++GO:0030165///PDZ domain binding+++GO:0098641///cadherin binding involved in cell-cell adhesion+++GO:0070064///proline-rich region binding+++GO:0042802///identical protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0097110///scaffold protein binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding","GO:0010976///positive regulation of neuron projection development+++GO:1905232///cellular response to L-glutamate+++GO:2000463///positive regulation of excitatory postsynaptic potential+++GO:0099564///modification of synaptic structure, modulating synaptic transmission+++GO:0008286///insulin receptor signaling pathway+++GO:0098609///cell-cell adhesion+++GO:0050804///modulation of chemical synaptic transmission+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:0007009///plasma membrane organization+++GO:0007420///brain development+++GO:0030182///neuron differentiation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0016358///dendrite development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0048167///regulation of synaptic plasticity+++GO:0008360///regulation of cell shape+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030838///positive regulation of actin filament polymerization+++GO:0051764///actin crosslink formation+++GO:0035418///protein localization to synapse+++GO:0007409///axonogenesis+++GO:0051017///actin filament bundle assembly+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0009617///response to bacterium","IPR030128///I-BAR domain containing protein IRSp53+++IPR001452///SH3 domain+++IPR013606///IMD/I-BAR domain+++IPR035594///IRSp53, SH3 domain+++IPR027681///I-BAR domain containing protein IRSp53/IRTKS/Pinkbar+++IPR036028///SH3-like domain superfamily+++IPR027267///AH/BAR domain superfamily","[BAIP2_HUMAN|Reviewed]RecName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2; Short=BAI-associated protein 2; Short=BAI1-associated protein 2; Short=Protein BAP2; AltName: Full=Fas ligand-associated factor 3; Short=FLAF3; AltName: Full=Insulin receptor substrate p53/p58; Short=IRS-58; Short=IRSp53/58; AltName: Full=Insulin receptor substrate protein of 53 kDa; Short=IRSp53; Short=Insulin receptor substrate p53;+++[B4DWA1_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000391837}; SubName: Full=cDNA FLJ55181, highly similar to Brain-specific angiogenesis inhibitor1-associated protein 2 {ECO:0000313|EMBL:BAG62963.1};+++[I3L0M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458202}; Flags: Fragment;+++[I3L0Y9_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458440}; Flags: Fragment;+++[I3L113_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458494}; Flags: Fragment;+++[I3L125_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458522}; Flags: Fragment;+++[I3L1C8_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000458735}; Flags: Fragment;+++[I3L2J6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459730};+++[I3L2M4_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000459787}; Flags: Fragment;+++[I3L327_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460131}; Flags: Fragment;+++[I3L3C5_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460344};+++[I3L3C6_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460350}; Flags: Fragment;+++[I3L3J7_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000460492};+++[I3L4A3_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461101}; Flags: Fragment;+++[I3L4C2_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461144};+++[I3L526_HUMAN|Unreviewed]SubName: Full=Brain-specific angiogenesis inhibitor 1-associated protein 2 {ECO:0000313|Ensembl:ENSP00000461736}; Flags: Fragment;"]
[10459,"'MAD2L2'",355,275,315,"04110///Cell cycle+++05100///Bacterial invasion of epithelial cells+++04114///Oocyte meiosis+++05131///Shigellosis+++04914///Progesterone-mediated oocyte maturation","H00238///Fanconi anemia","M00293///DNA polymerase zeta complex",null,"GO:0005730///nucleolus+++GO:0005856///cytoskeleton+++GO:0035861///site of double-strand break+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0016035///zeta DNA polymerase complex+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005680///anaphase-promoting complex","GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0008432///JUN kinase binding+++GO:0005515///protein binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:1904667///negative regulation of ubiquitin protein ligase activity+++GO:0006281///DNA repair+++GO:0042772///DNA damage response, signal transduction resulting in transcription+++GO:0045830///positive regulation of isotype switching+++GO:0006302///double-strand break repair+++GO:0042177///negative regulation of protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0042276///error-prone translesion synthesis+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010719///negative regulation of epithelial to mesenchymal transition+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007049///cell cycle+++GO:0007015///actin filament organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000048///negative regulation of cell-cell adhesion mediated by cadherin+++GO:0051301///cell division+++GO:0010944///negative regulation of transcription by competitive promoter binding+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:2001034///positive regulation of double-strand break repair via nonhomologous end joining","IPR003511///HORMA domain+++IPR036570///HORMA domain superfamily","[MD2L2_HUMAN|Reviewed]RecName: Full=Mitotic spindle assembly checkpoint protein MAD2B; AltName: Full=Mitotic arrest deficient 2-like protein 2; Short=MAD2-like protein 2; AltName: Full=REV7 homolog; Short=hREV7;+++[A0A024R4I4_HUMAN|Unreviewed]SubName: Full=MAD2 mitotic arrest deficient-like 2 (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71698.1};+++[B1AK43_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000411807}; Flags: Fragment;+++[B1AK44_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000365857};+++[B1AK45_HUMAN|Unreviewed]SubName: Full=Mitotic spindle assembly checkpoint protein MAD2B {ECO:0000313|Ensembl:ENSP00000400982}; Flags: Fragment;"]
[10460,"'TACC3'",74,49,61.5,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0072686///mitotic spindle+++GO:0005819///spindle+++GO:0005815///microtubule organizing center+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005515///protein binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization+++GO:1902850///microtubule cytoskeleton organization involved in mitosis+++GO:0060236///regulation of mitotic spindle organization","IPR039915///Alp7/TACC+++IPR007707///Transforming acidic coiled-coil-containing protein, C-terminal","[TACC3_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 3; AltName: Full=ERIC-1;+++[C9JA91_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418095}; Flags: Fragment;+++[C9JWI7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000419210}; Flags: Fragment;+++[E7EMT0_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000415914}; Flags: Fragment;+++[F8WC55_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000418727};+++[H0Y8F2_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000420838}; Flags: Fragment;+++[Q8IX09_HUMAN|Unreviewed]SubName: Full=Erythropoietin induced cDNA-1 transcript variant 2 {ECO:0000313|EMBL:AAN76993.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 3 {ECO:0000313|Ensembl:ENSP00000478580};"]
[10461,"'MERTK'",93,64,78.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016028///rhabdomere+++GO:0005737///cytoplasm+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0001750///photoreceptor outer segment","GO:0000166///nucleotide binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0017147///Wnt-protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity","GO:0030154///cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007283///spermatogenesis+++GO:0060068///vagina development+++GO:0032940///secretion by cell+++GO:0030168///platelet activation+++GO:0097350///neutrophil clearance+++GO:0001779///natural killer cell differentiation+++GO:2000107///negative regulation of leukocyte apoptotic process+++GO:0043491///protein kinase B signaling+++GO:0050766///positive regulation of phagocytosis+++GO:0050900///leukocyte migration+++GO:0006909///phagocytosis+++GO:0043277///apoptotic cell clearance+++GO:0009968///negative regulation of signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0007267///cell-cell signaling+++GO:0001818///negative regulation of cytokine production+++GO:0007166///cell surface receptor signaling pathway+++GO:0060041///retina development in camera-type eye+++GO:0016055///Wnt signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0016310///phosphorylation+++GO:0051250///negative regulation of lymphocyte activation+++GO:0018108///peptidyl-tyrosine phosphorylation","IPR020635///Tyrosine-protein kinase, catalytic domain+++IPR011009///Protein kinase-like domain superfamily+++IPR013151///Immunoglobulin+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR008266///Tyrosine-protein kinase, active site+++IPR003961///Fibronectin type III+++IPR000719///Protein kinase domain+++IPR036116///Fibronectin type III superfamily+++IPR003599///Immunoglobulin subtype+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR017441///Protein kinase, ATP binding site+++IPR007110///Immunoglobulin-like domain","[MERTK_HUMAN|Reviewed]RecName: Full=Tyrosine-protein kinase Mer; EC=2.7.10.1; AltName: Full=Proto-oncogene c-Mer; AltName: Full=Receptor tyrosine kinase MerTK; Flags: Precursor;+++[A0A087WZQ5_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000482824};+++[E9PD22_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000402129};+++[E9PHX8_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000387277};+++[H7C3L9_HUMAN|Unreviewed]SubName: Full=Tyrosine-protein kinase Mer {ECO:0000313|Ensembl:ENSP00000412660}; Flags: Fragment;+++[Q1RMG3_HUMAN|Unreviewed]SubName: Full=MERTK protein {ECO:0000313|EMBL:AAI14919.1};+++[Q53QW0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAX93144.1}; Flags: Fragment;+++[Q53R53_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein MERTK {ECO:0000313|EMBL:AAY24213.1}; Flags: Fragment;"]
[10463,"'SLC30A9'",487,498,492.5,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0003682///chromatin binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008324///cation transmembrane transporter activity+++GO:0016922///nuclear receptor binding","GO:0006289///nucleotide-excision repair+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006812///cation transport+++GO:0006811///ion transport+++GO:0006882///cellular zinc ion homeostasis+++GO:0006829///zinc ion transport","IPR037129///XPA domain superfamily+++IPR002524///Cation efflux protein+++IPR027469///Cation efflux transmembrane domain superfamily+++IPR009061///Putative DNA-binding domain superfamily","[ZNT9_HUMAN|Reviewed]RecName: Full=Zinc transporter 9; Short=ZnT-9; AltName: Full=Human embryonic lung protein {ECO:0000303|PubMed:10409434}; Short=HuEL {ECO:0000303|PubMed:10409434}; AltName: Full=Solute carrier family 30 member 9;+++[A0A024R9W8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 (Zinc transporter), member 9, isoform CRA_b {ECO:0000313|EMBL:EAW92999.1};+++[A0A0S2Z512_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 2 {ECO:0000313|EMBL:ALQ33985.1};+++[A0A0S2Z514_HUMAN|Unreviewed]SubName: Full=Solute carrier family 30 member 9 isoform 1 {ECO:0000313|EMBL:ALQ33984.1}; Flags: Fragment;+++[D6R9M6_HUMAN|Unreviewed]SubName: Full=Zinc transporter 9 {ECO:0000313|Ensembl:ENSP00000423529};"]
[10464,"'PIBF1'",121,140,130.5,"03018///RNA degradation+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00530///Joubert syndrome","M00391///Exosome, eukaryotes",null,"GO:0005815///microtubule organizing center+++GO:0034451///centriolar satellite+++GO:0005856///cytoskeleton+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0005813///centrosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0005136///interleukin-4 receptor binding","GO:0032733///positive regulation of interleukin-10 production+++GO:1905515///non-motile cilium assembly+++GO:0042976///activation of Janus kinase activity+++GO:0071539///protein localization to centrosome+++GO:0090307///mitotic spindle assembly+++GO:0060271///cilium assembly+++GO:0002376///immune system process+++GO:0032695///negative regulation of interleukin-12 production+++GO:0032815///negative regulation of natural killer cell activation+++GO:0031393///negative regulation of prostaglandin biosynthetic process+++GO:0042532///negative regulation of tyrosine phosphorylation of STAT protein+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0007080///mitotic metaphase plate congression","IPR026205///Progesterone-induced-blocking factor 1","[PIBF1_HUMAN|Reviewed]RecName: Full=Progesterone-induced-blocking factor 1; Short=PIBF; AltName: Full=Centrosomal protein of 90 kDa; Short=CEP90 {ECO:0000303|PubMed:21224392};+++[A0A087WUI6_HUMAN|Unreviewed]SubName: Full=Progesterone-induced-blocking factor 1 {ECO:0000313|Ensembl:ENSP00000478697};+++[Q05DN0_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH06009.1}; Flags: Fragment;+++[Q4G0R1_HUMAN|Unreviewed]SubName: Full=PIBF1 protein {ECO:0000313|EMBL:AAH41806.1};"]
[10465,"'PPIH'",140,106,123,"03040///Spliceosome",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0071001///U4/U6 snRNP+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0051082///unfolded protein binding+++GO:0016018///cyclosporin A binding+++GO:0016853///isomerase activity+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding","GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0006457///protein folding+++GO:0045070///positive regulation of viral genome replication+++GO:0065003///protein-containing complex assembly","IPR024936///Cyclophilin-type peptidyl-prolyl cis-trans isomerase+++IPR002130///Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain+++IPR029000///Cyclophilin-like domain superfamily+++IPR020892///Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site","[PPIH_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase H; Short=PPIase H; EC=5.2.1.8 {ECO:0000269|PubMed:20676357}; AltName: Full=Rotamase H; AltName: Full=Small nuclear ribonucleoprotein particle-specific cyclophilin H; Short=CypH; AltName: Full=U-snRNP-associated cyclophilin SnuCyp-20; Short=USA-CYP;+++[A6NM32_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000361629};+++[C9JAN8_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase H {ECO:0000313|Ensembl:ENSP00000405493}; Flags: Fragment;+++[C9JQD4_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[H0YEL5_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH36_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019}; Flags: Fragment;+++[Q6FH57_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[10466,"'COG5'",424,545,484.5,"04140///Autophagy - animal+++04910///Insulin signaling pathway+++04137///Mitophagy - animal","H00119///Congenital disorders of glycosylation (CDG) type II",null,null,"GO:0017119///Golgi transport complex+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0032588///trans-Golgi network membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport","IPR019465///Conserved oligomeric Golgi complex subunit 5","[COG5_HUMAN|Reviewed]RecName: Full=Conserved oligomeric Golgi complex subunit 5; Short=COG complex subunit 5; AltName: Full=13S Golgi transport complex 90 kDa subunit; Short=GTC-90; AltName: Full=Component of oligomeric Golgi complex 5; AltName: Full=Golgi transport complex 1;+++[U3KQU7_HUMAN|Unreviewed]SubName: Full=Conserved oligomeric Golgi complex subunit 5 {ECO:0000313|Ensembl:ENSP00000476238}; Flags: Fragment;"]
[10467,"'ZNHIT1'",2022,1452,1737,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000812///Swr1 complex","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding","GO:0006338///chromatin remodeling+++GO:0031063///regulation of histone deacetylation+++GO:0043486///histone exchange","IPR007529///Zinc finger, HIT-type+++IPR039723///Vps71/ZNHIT1","[ZNHI1_HUMAN|Reviewed]RecName: Full=Zinc finger HIT domain-containing protein 1; AltName: Full=Cyclin-G1-binding protein 1; AltName: Full=Zinc finger protein subfamily 4A member 1; AltName: Full=p18 Hamlet;"]
[10468,"'FST'",271,300,285.5,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0043395///heparan sulfate proteoglycan binding+++GO:0048185///activin binding+++GO:0038102///activin receptor antagonist activity","GO:0051798///positive regulation of hair follicle development+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032926///negative regulation of activin receptor signaling pathway","IPR017878///TB domain+++IPR002350///Kazal domain+++IPR003645///Follistatin-like, N-terminal+++IPR015369///Follistatin/Osteonectin EGF domain+++IPR036058///Kazal domain superfamily+++IPR036773///TGF-beta binding (TB) domain superfamily","[FST_HUMAN|Reviewed]RecName: Full=Follistatin; Short=FS; AltName: Full=Activin-binding protein; Flags: Precursor;+++[A0A024QZU6_HUMAN|Unreviewed]SubName: Full=Follistatin, isoform CRA_c {ECO:0000313|EMBL:EAW54883.1};+++[H0YA75_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426315}; Flags: Fragment;+++[H0YAF9_HUMAN|Unreviewed]SubName: Full=Follistatin {ECO:0000313|Ensembl:ENSP00000426971}; Flags: Fragment;+++[Q6FHE1_HUMAN|Unreviewed]SubName: Full=FST protein {ECO:0000313|EMBL:CAG46612.1};"]
[10469,"'TIMM44'",420,357,388.5,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0051087///chaperone binding","GO:0015031///protein transport+++GO:0006626///protein targeting to mitochondrion+++GO:0030150///protein import into mitochondrial matrix","IPR032710///NTF2-like domain superfamily+++IPR017303///Mitochondrial import inner membrane translocase subunit Tim44+++IPR039544///Tim44-like+++IPR007379///Tim44-like domain","[TIM44_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM44; Flags: Precursor;+++[M0QXM9_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469273}; Flags: Fragment;+++[M0QXU7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000469389}; Flags: Fragment;+++[M0R124_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000471596};+++[M0R301_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM44 {ECO:0000313|Ensembl:ENSP00000472916}; Flags: Fragment;"]
[1047,"'CLGN'",521,378,449.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope","GO:0005509///calcium ion binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0007338///single fertilization+++GO:0065003///protein-containing complex assembly+++GO:0007339///binding of sperm to zona pellucida","IPR001580///Calreticulin/calnexin+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR018124///Calreticulin/calnexin, conserved site+++IPR009033///Calreticulin/calnexin, P domain superfamily","[CLGN_HUMAN|Reviewed]RecName: Full=Calmegin; Flags: Precursor;+++[A0A140VKG2_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 79P {ECO:0000313|EMBL:AEE61299.1};"]
[10471,"'PFDN6'",258,197,227.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016272///prefoldin complex","GO:0051087///chaperone binding+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0051131///chaperone-mediated protein complex assembly","IPR002777///Prefoldin beta-like+++IPR009053///Prefoldin","[PFD6_HUMAN|Reviewed]RecName: Full=Prefoldin subunit 6; AltName: Full=Protein Ke2;+++[A2AB88_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6 {ECO:0000313|Ensembl:ENSP00000420135};+++[I7HJT1_HUMAN|Unreviewed]SubName: Full=HLA class II region expressed gene KE2 {ECO:0000313|EMBL:CAC88187.1}; SubName: Full=Prefoldin subunit 6, isoform CRA_a {ECO:0000313|EMBL:EAX03705.1};+++[Q5STK2_HUMAN|Unreviewed]SubName: Full=Prefoldin subunit 6, isoform CRA_b {ECO:0000313|EMBL:EAX03706.1}; SubName: Full=cDNA, FLJ92435, Homo sapiens HLA class II region expressed gene KE2 (HKE2), mRNA {ECO:0000313|EMBL:BAG35084.1};"]
[10472,"'ZBTB18'",349,415,382,{"$nulls":4},"GO:0005634///nucleus+++GO:0000228///nuclear chromosome","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007519///skeletal muscle tissue development+++GO:0007275///multicellular organism development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily","[ZBT18_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 18; AltName: Full=58 kDa repressor protein; AltName: Full=Transcriptional repressor RP58; AltName: Full=Translin-associated zinc finger protein 1; Short=TAZ-1; AltName: Full=Zinc finger protein 238; AltName: Full=Zinc finger protein C2H2-171;+++[A0A024R5T6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 238, isoform CRA_a {ECO:0000313|EMBL:EAW77099.1};"]
[10473,"'HMGN4'",357,292,324.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0000785///chromatin","GO:0031492///nucleosomal DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding",null,"IPR000079///High mobility group protein HMGN","[HMGN4_HUMAN|Reviewed]RecName: Full=High mobility group nucleosome-binding domain-containing protein 4; AltName: Full=Non-histone chromosomal protein HMG-17-like 3; Short=Non-histone chromosomal protein;+++[A0A024R046_HUMAN|Unreviewed]SubName: Full=High mobility group nucleosomal binding domain 4, isoform CRA_a {ECO:0000313|EMBL:EAW55589.1};"]
[10474,"'TADA3'",3533.35,2921.4,3227.375,"05165///Human papillomavirus infection",{"$nulls":3},"GO:0000124///SAGA complex+++GO:0005622///intracellular+++GO:0030914///STAGA complex+++GO:0072686///mitotic spindle+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0033276///transcription factor TFTC complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0016922///nuclear receptor binding+++GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0019904///protein domain specific binding","GO:0043966///histone H3 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0090043///regulation of tubulin deacetylation+++GO:0000278///mitotic cell cycle+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043967///histone H4 acetylation+++GO:0010628///positive regulation of gene expression+++GO:0016579///protein deubiquitination+++GO:0031063///regulation of histone deacetylation+++GO:0001932///regulation of protein phosphorylation+++GO:0031647///regulation of protein stability+++GO:0030520///intracellular estrogen receptor signaling pathway","IPR019340///Histone acetyltransferases subunit 3","[TADA3_HUMAN|Reviewed]RecName: Full=Transcriptional adapter 3; AltName: Full=ADA3 homolog; Short=hADA3; AltName: Full=STAF54; AltName: Full=Transcriptional adapter 3-like; Short=ADA3-like protein;+++[A0A024R2D7_HUMAN|Unreviewed]SubName: Full=Transcriptional adaptor 3 (NGG1 homolog, yeast)-like, isoform CRA_a {ECO:0000313|EMBL:EAW63997.1};+++[A8K899_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77724, highly similar to Homo sapiens transcriptional adaptor 3 (NGG1 homolog, yeast)-like (TADA3L), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84953.1};+++[C9JMS0_HUMAN|Unreviewed]SubName: Full=Transcriptional adapter 3 {ECO:0000313|Ensembl:ENSP00000395073}; Flags: Fragment;"]
[10475,"'TRIM38'",556,463.06,509.53,{"$nulls":4},"GO:0005829///cytosol+++GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0050687///negative regulation of defense response to virus+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0045070///positive regulation of viral genome replication+++GO:0002376///immune system process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0046598///positive regulation of viral entry into host cell+++GO:0032648///regulation of interferon-beta production+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0070936///protein K48-linked ubiquitination+++GO:0045087///innate immune response+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0051092///positive regulation of NF-kappaB transcription factor activity","IPR006574///SPRY-associated+++IPR003879///Butyrophylin-like, SPRY domain+++IPR017907///Zinc finger, RING-type, conserved site+++IPR001870///B30.2/SPRY domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR000315///B-box-type zinc finger+++IPR003877///SPRY domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR035790///E3 ubiquitin-protein ligase TRIM38, PRY/SPRY domain","[TRI38_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM38; EC=2.3.2.27; AltName: Full=RING finger protein 15; AltName: Full=RING-type E3 ubiquitin transferase TRIM38 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 38; AltName: Full=Zinc finger protein RoRet;+++[A0A024QZY4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 38, isoform CRA_a {ECO:0000313|EMBL:EAW55505.1};"]
[10476,"'ATP5PD'",1091,739,915,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++05016///Huntington's disease+++05010///Alzheimer's disease+++05012///Parkinson's disease+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0000274///mitochondrial proton-transporting ATP synthase, stator stalk+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005654///nucleoplasm+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005743///mitochondrial inner membrane","GO:0022857///transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0015078///proton transmembrane transporter activity","GO:0015986///ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0006811///ion transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0006754///ATP biosynthetic process+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport","IPR008689///ATP synthase, F0 complex, subunit D, mitochondrial+++IPR036228///ATP synthase, F0 complex, subunit D superfamily, mitochondrial","[ATP5H_HUMAN|Reviewed]RecName: Full=ATP synthase subunit d, mitochondrial {ECO:0000305}; Short=ATPase subunit d; AltName: Full=ATP synthase peripheral stalk subunit d {ECO:0000305};+++[A0PJH2_HUMAN|Unreviewed]SubName: Full=ATP5H protein {ECO:0000313|EMBL:AAH29392.1}; Flags: Fragment;+++[F5H608_HUMAN|Unreviewed]SubName: Full=ATP synthase peripheral stalk subunit d {ECO:0000313|Ensembl:ENSP00000437996};+++[L8E9E1_HUMAN|Unreviewed]SubName: Full=Alternative protein ATP5H {ECO:0000313|EMBL:CCQ43351.1};"]
[10477,"'UBE2E3'",486,438,462,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0070979///protein K11-linked ubiquitination+++GO:0016567///protein ubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0040008///regulation of growth+++GO:0070936///protein K48-linked ubiquitination","IPR000608///Ubiquitin-conjugating enzyme E2+++IPR016135///Ubiquitin-conjugating enzyme/RWD-like+++IPR023313///Ubiquitin-conjugating enzyme, active site","[UB2E3_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 E3; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=E2 ubiquitin-conjugating enzyme E3; AltName: Full=UbcH9; AltName: Full=Ubiquitin carrier protein E3; AltName: Full=Ubiquitin-conjugating enzyme E2-23 kDa; AltName: Full=Ubiquitin-protein ligase E3;+++[A0A1B0GX65_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473525}; Flags: Fragment;+++[R4GMM6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473264};+++[R4GN77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473521}; Flags: Fragment;+++[R4GND1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473591};+++[R4GNG6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 E3 {ECO:0000313|Ensembl:ENSP00000473642};"]
[10478,"'SLC25A17'",187,182,184.5,"04146///Peroxisome",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005779///integral component of peroxisomal membrane+++GO:0005778///peroxisomal membrane+++GO:0016021///integral component of membrane+++GO:0005777///peroxisome+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane","GO:0015228///coenzyme A transmembrane transporter activity+++GO:0000295///adenine nucleotide transmembrane transporter activity+++GO:0015230///FAD transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0080122///AMP transmembrane transporter activity+++GO:0005347///ATP transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051087///chaperone binding+++GO:0044610///FMN transmembrane transporter activity+++GO:0015217///ADP transmembrane transporter activity+++GO:0051724///NAD transmembrane transporter activity","GO:0080121///AMP transport+++GO:0035349///coenzyme A transmembrane transport+++GO:0006635///fatty acid beta-oxidation+++GO:0001561///fatty acid alpha-oxidation+++GO:0015908///fatty acid transport+++GO:0015867///ATP transport+++GO:0015866///ADP transport+++GO:0051182///coenzyme transport+++GO:0035352///NAD transmembrane transport+++GO:0035350///FAD transmembrane transport+++GO:0055085///transmembrane transport+++GO:1901679///nucleotide transmembrane transport","IPR002030///Mitochondrial carrier UCP-like+++IPR018108///Mitochondrial substrate/solute carrier+++IPR023395///Mitochondrial carrier domain superfamily+++IPR002067///Mitochondrial carrier protein+++IPR040062///Mitochondrial carrier domain protein","[PM34_HUMAN|Reviewed]RecName: Full=Peroxisomal membrane protein PMP34; AltName: Full=34 kDa peroxisomal membrane protein; AltName: Full=Solute carrier family 25 member 17;+++[B0QYW5_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000385303};+++[B1AHN4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000404200}; Flags: Fragment;+++[B4DP73_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57410, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG60485.1};+++[B4DU97_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57596, highly similar to Peroxisomal membrane protein PMP34 {ECO:0000313|EMBL:BAG62259.1};+++[F2Z2I9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000410565};+++[F6RTR7_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000438355};+++[F8WA85_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000263255};+++[F8WBA4_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000390502};+++[F8WCH6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000400053};+++[F8WCN9_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000416618};+++[F8WE74_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000394539};+++[F8WEC6_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000388966};+++[F8WF87_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein PMP34 {ECO:0000313|Ensembl:ENSP00000407096};"]
[10479,"'SLC9A6'",226,243,234.5,null,"H01914///Christianson syndrome",null,null,"GO:0043679///axon terminus+++GO:0030425///dendrite+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0055038///recycling endosome membrane+++GO:0031901///early endosome membrane+++GO:0044308///axonal spine+++GO:0005770///late endosome+++GO:0005789///endoplasmic reticulum membrane","GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity","GO:0031547///brain-derived neurotrophic factor receptor signaling pathway+++GO:0050808///synapse organization+++GO:0098719///sodium ion import across plasma membrane+++GO:0051386///regulation of neurotrophin TRK receptor signaling pathway+++GO:0060996///dendritic spine development+++GO:0048675///axon extension+++GO:0048812///neuron projection morphogenesis+++GO:0051453///regulation of intracellular pH+++GO:0006811///ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0097484///dendrite extension","IPR002090///Na+/H+ exchanger, isoform 6 (NHE6)+++IPR006153///Cation/H+ exchanger+++IPR018422///Cation/H+ exchanger, CPA1 family+++IPR004709///Na+/H+ exchanger","[SL9A6_HUMAN|Reviewed]RecName: Full=Sodium/hydrogen exchanger 6; AltName: Full=Na(+)/H(+) exchanger 6; Short=NHE-6; AltName: Full=Solute carrier family 9 member 6;+++[A0A1B0GV11_HUMAN|Unreviewed]RecName: Full=Sodium/hydrogen exchanger {ECO:0000256|RuleBase:RU003722};"]
[1048,"'CEACAM5'",0,2,1,{"$nulls":4},"GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0071575///integral component of external side of plasma membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0031225///anchored component of membrane+++GO:0016324///apical plasma membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity+++GO:0034235///GPI anchor binding+++GO:0042802///identical protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0034109///homotypic cell-cell adhesion+++GO:0010832///negative regulation of myotube differentiation+++GO:2000811///negative regulation of anoikis+++GO:0050900///leukocyte migration","IPR013106///Immunoglobulin V-set domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR003598///Immunoglobulin subtype 2+++IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold","[CEAM5_HUMAN|Reviewed]RecName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5; AltName: Full=Carcinoembryonic antigen; Short=CEA; AltName: Full=Meconium antigen 100; AltName: CD_antigen=CD66e; Flags: Precursor;+++[A0A024R0K5_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5, isoform CRA_a {ECO:0000313|EMBL:EAW57060.1};+++[A0A087WYX0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000482157};+++[M0QX98_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000468997}; Flags: Fragment;+++[M0R3J1_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000473252}; Flags: Fragment;+++[Q53G30_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 variant {ECO:0000313|EMBL:BAD96821.1}; Flags: Fragment;+++[Q8N4D0_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 {ECO:0000313|EMBL:AAH34671.1};+++[T2HUW8_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 3D {ECO:0000313|EMBL:BAN83790.1};+++[T2HVB7_HUMAN|Unreviewed]SubName: Full=Carcinoembryonic antigen-related cell adhesion molecule 5 isoform 5D {ECO:0000313|EMBL:BAN83789.1};"]
[10480,"'EIF3M'",1237,1106,1171.5,{"$nulls":4},"GO:0033290///eukaryotic 48S preinitiation complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0031369///translation initiation factor binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding","GO:0006412///translation+++GO:0006413///translational initiation+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation","IPR036390///Winged helix DNA-binding domain superfamily+++IPR027528///Eukaryotic translation initiation factor 3 subunit M+++IPR016024///Armadillo-type fold+++IPR000717///Proteasome component (PCI) domain","[EIF3M_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000255|HAMAP-Rule:MF_03012}; Short=eIF3m {ECO:0000255|HAMAP-Rule:MF_03012}; AltName: Full=Fetal lung protein B5; Short=hFL-B5; AltName: Full=PCI domain-containing protein 1;+++[E7ESM3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435501};+++[E9PN86_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432891}; Flags: Fragment;+++[E9PRI2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432286};+++[E9PRY0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000434080};+++[E9PSB3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000435834};+++[H0YCQ8_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000432139}; Flags: Fragment;+++[J3KNJ2_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit M {ECO:0000313|Ensembl:ENSP00000319910}; Flags: Fragment;"]
[10481,"'HOXB13'",2,2,2,{"$nulls":4},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008327///methyl-CpG binding","GO:0007275///multicellular organism development+++GO:0008544///epidermis development+++GO:0040008///regulation of growth+++GO:0001525///angiogenesis+++GO:0030850///prostate gland development+++GO:0060743///epithelial cell maturation involved in prostate gland development+++GO:0033574///response to testosterone+++GO:0002009///morphogenesis of an epithelium+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060527///prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis+++GO:0009611///response to wounding","IPR001356///Homeobox domain+++IPR022067///Homeobox protein Hox1A3 N-terminal+++IPR009057///Homeobox-like domain superfamily+++IPR017970///Homeobox, conserved site","[HXB13_HUMAN|Reviewed]RecName: Full=Homeobox protein Hox-B13;+++[Q4KR72_HUMAN|Unreviewed]SubName: Full=PSGD protein {ECO:0000313|EMBL:AAY17396.1};+++[V5QRV9_HUMAN|Unreviewed]SubName: Full=Homeobox protein Hox-B13 variant {ECO:0000313|EMBL:AHB20311.1};"]
[10482,"'NXF1'",1153,1193,1173,"05168///Herpes simplex infection+++03013///RNA transport+++03015///mRNA surveillance pathway+++05164///Influenza A+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0000346///transcription export complex+++GO:0042405///nuclear inclusion body+++GO:0005737///cytoplasm+++GO:0005643///nuclear pore+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding","GO:0051028///mRNA transport+++GO:0016032///viral process+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0006406///mRNA export from nucleus","IPR015245///Nuclear RNA export factor Tap, RNA-binding domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR009060///UBA-like superfamily+++IPR001611///Leucine-rich repeat+++IPR005637///TAP C-terminal (TAP-C) domain+++IPR035979///RNA-binding domain superfamily+++IPR032710///NTF2-like domain superfamily+++IPR018222///Nuclear transport factor 2, eukaryote+++IPR002075///Nuclear transport factor 2+++IPR030217///Nuclear RNA export factor+++IPR032675///Leucine-rich repeat domain superfamily","[NXF1_HUMAN|Reviewed]RecName: Full=Nuclear RNA export factor 1; AltName: Full=Tip-associated protein; AltName: Full=Tip-associating protein; AltName: Full=mRNA export factor TAP;+++[A0A024R5A9_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW74104.1};+++[B4E227_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61053, highly similar to Nuclear RNA export factor 1 {ECO:0000313|EMBL:BAG64989.1};+++[E9PIN3_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000435742}; Flags: Fragment;+++[E9PLA7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000431381}; Flags: Fragment;+++[E9PMV7_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000437296}; Flags: Fragment;+++[E9PQA4_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000432530};+++[H0YDU0_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 {ECO:0000313|Ensembl:ENSP00000434301}; Flags: Fragment;+++[Q59E96_HUMAN|Unreviewed]SubName: Full=Nuclear RNA export factor 1 variant {ECO:0000313|EMBL:BAD93152.1}; Flags: Fragment;"]
[10483,"'SEC23B'",790,833,811.5,"04141///Protein processing in endoplasmic reticulum","H01105///Cranio-lenticulo-sutural dysplasia (CLSD)+++H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)","M00404///COPII complex",null,"GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0012505///endomembrane system+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0030127///COPII vesicle coat","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0043547///positive regulation of GTPase activity+++GO:0008360///regulation of cell shape+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0090114///COPII-coated vesicle budding+++GO:0003400///regulation of COPII vesicle coating","IPR006896///Sec23/Sec24, trunk domain+++IPR007123///Gelsolin-like domain+++IPR036174///Zinc finger, Sec23/Sec24-type superfamily+++IPR036465///von Willebrand factor A-like domain superfamily+++IPR029006///ADF-H/Gelsolin-like domain superfamily+++IPR012990///Sec23/Sec24 beta-sandwich+++IPR036175///Sec23/Sec24 helical domain superfamily+++IPR036180///Gelsolin-like domain superfamily+++IPR006900///Sec23/Sec24, helical domain+++IPR037550///Sec23, C-terminal+++IPR006895///Zinc finger, Sec23/Sec24-type+++IPR037364///Protein transport protein Sec23","[SC23B_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23B {ECO:0000305}; Short=hSec23B {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein B;+++[A0A2R8Y633_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8Y7S7_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YF30_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[A0A2R8YFH5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[Q5QPE1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[Q5QPE2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;"]
[10484,"'SEC23A'",1517,1883,1700,"04141///Protein processing in endoplasmic reticulum","H01222///Cowden syndrome+++H00917///Congenital dyserythropoietic anemias (CDAs)+++H01105///Cranio-lenticulo-sutural dysplasia (CLSD)","M00404///COPII complex",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0030127///COPII vesicle coat+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0019898///extrinsic component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0070971///endoplasmic reticulum exit site","GO:0005096///GTPase activator activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0090114///COPII-coated vesicle budding+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0090110///cargo loading into COPII-coated vesicle+++GO:0015031///protein transport+++GO:0072659///protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016236///macroautophagy+++GO:0016192///vesicle-mediated transport+++GO:0003400///regulation of COPII vesicle coating+++GO:0008360///regulation of cell shape+++GO:0007030///Golgi organization+++GO:0006886///intracellular protein transport+++GO:0048208///COPII vesicle coating+++GO:0043547///positive regulation of GTPase activity","IPR036465///von Willebrand factor A-like domain superfamily+++IPR006896///Sec23/Sec24, trunk domain+++IPR036174///Zinc finger, Sec23/Sec24-type superfamily+++IPR036180///Gelsolin-like domain superfamily+++IPR037550///Sec23, C-terminal+++IPR036175///Sec23/Sec24 helical domain superfamily+++IPR012990///Sec23/Sec24 beta-sandwich+++IPR007123///Gelsolin-like domain+++IPR029006///ADF-H/Gelsolin-like domain superfamily+++IPR006900///Sec23/Sec24, helical domain+++IPR006895///Zinc finger, Sec23/Sec24-type+++IPR037364///Protein transport protein Sec23","[SC23A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec23A {ECO:0000305}; Short=hSec23A {ECO:0000303|PubMed:8898360}; AltName: Full=SEC23-related protein A;+++[F5H365_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V1W4_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V2R6_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V3G5_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V4Q2_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[G3V4V1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5K1_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030}; Flags: Fragment;+++[G3V5X8_HUMAN|Unreviewed]RecName: Full=Protein transport protein SEC23 {ECO:0000256|RuleBase:RU365030};+++[L8ECD0_HUMAN|Unreviewed]SubName: Full=Alternative protein SEC23A {ECO:0000313|EMBL:CCQ43352.1};"]
[10485,"'C1orf61'",2,1,1.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003674///molecular_function","GO:0045944///positive regulation of transcription by RNA polymerase II","IPR031751///Protein of unknown function DUF4735","[CROC4_HUMAN|Reviewed]RecName: Full=Protein CROC-4; AltName: Full=Contingent replication of cDNA 4;+++[H0Y3T1_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000383776}; Flags: Fragment;+++[H3BLW3_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000357225}; Flags: Fragment;+++[Q6PB34_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH59943.1}; Flags: Fragment;+++[Q86W69_HUMAN|Unreviewed]SubName: Full=C1orf61 protein {ECO:0000313|EMBL:AAH50448.1}; SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000310651}; Flags: Fragment;+++[X6R5L4_HUMAN|Unreviewed]SubName: Full=Protein CROC-4 {ECO:0000313|Ensembl:ENSP00000350661}; Flags: Fragment;"]
[10486,"'CAP2'",1701,1954,1827.5,"04137///Mitophagy - animal+++03010///Ribosome+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly","M00177///Ribosome, eukaryotes",null,"GO:0005886///plasma membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0014069///postsynaptic density+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:1990904///ribonucleoprotein complex","GO:0003729///mRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003677///DNA binding+++GO:0003723///RNA binding+++GO:0008179///adenylate cyclase binding+++GO:0042803///protein homodimerization activity+++GO:0003779///actin binding+++GO:0042802///identical protein binding","GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0007190///activation of adenylate cyclase activity+++GO:0002181///cytoplasmic translation+++GO:0007163///establishment or maintenance of cell polarity+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0006364///rRNA processing+++GO:0008154///actin polymerization or depolymerization+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0007165///signal transduction+++GO:0000902///cell morphogenesis+++GO:0042273///ribosomal large subunit biogenesis+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","IPR013912///Adenylate cyclase-associated CAP, C-terminal+++IPR028418///Adenylyl cyclase-associated protein CAP2+++IPR028417///CAP, conserved site, C-terminal+++IPR016098///Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal+++IPR001837///Adenylate cyclase-associated CAP+++IPR018106///CAP, conserved site, N-terminal+++IPR036223///Adenylate cyclase-associated CAP, C-terminal  superfamily+++IPR017901///C-CAP/cofactor C-like domain+++IPR006599///CARP motif+++IPR036222///Adenylate cyclase-associated CAP, N-terminal  domain superfamily+++IPR013992///Adenylate cyclase-associated CAP, N-terminal","[CAP2_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 2; Short=CAP 2;+++[A0A087WZ15_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[A0A087X0J3_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[B7Z385_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[E9PDI2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[F8WDB9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000420615};+++[F8WEW0_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 2 {ECO:0000313|Ensembl:ENSP00000419906};+++[Q5JPJ8_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};"]
[10487,"'CAP1'",11903,11838,11870.5,"01100///Metabolic pathways+++04142///Lysosome+++01212///Fatty acid metabolism+++00062///Fatty acid elongation","H00149///Neuronal ceroid lipofuscinosis (NCL)+++H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,"R01274///palmitoyl-CoA hydrolase Palmitoyl-CoA + H2O <=> CoA + Hexadecanoic acid","GO:0035578///azurophil granule lumen+++GO:0030424///axon+++GO:0005764///lysosome+++GO:0030425///dendrite+++GO:0045121///membrane raft+++GO:0005794///Golgi apparatus+++GO:0030864///cortical actin cytoskeleton+++GO:0016020///membrane+++GO:0005576///extracellular region+++GO:0005925///focal adhesion+++GO:0070062///extracellular exosome+++GO:0008021///synaptic vesicle+++GO:0005634///nucleus+++GO:0043025///neuronal cell body+++GO:0043202///lysosomal lumen+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0008179///adenylate cyclase binding+++GO:0008474///palmitoyl-(protein) hydrolase activity+++GO:0016290///palmitoyl-CoA hydrolase activity+++GO:0003779///actin binding","GO:0030163///protein catabolic process+++GO:0007269///neurotransmitter secretion+++GO:0006898///receptor-mediated endocytosis+++GO:0007042///lysosomal lumen acidification+++GO:0001667///ameboidal-type cell migration+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0008154///actin polymerization or depolymerization+++GO:0007420///brain development+++GO:0030149///sphingolipid catabolic process+++GO:0007601///visual perception+++GO:0007190///activation of adenylate cyclase activity+++GO:0051186///cofactor metabolic process+++GO:0016042///lipid catabolic process+++GO:0046949///fatty-acyl-CoA biosynthetic process+++GO:0043312///neutrophil degranulation+++GO:0051181///cofactor transport+++GO:0050803///regulation of synapse structure or activity+++GO:0002084///protein depalmitoylation+++GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0007268///chemical synaptic transmission+++GO:0006907///pinocytosis+++GO:0050896///response to stimulus+++GO:0048666///neuron development+++GO:0000902///cell morphogenesis+++GO:0007165///signal transduction+++GO:0032429///regulation of phospholipase A2 activity+++GO:0007625///grooming behavior+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0048549///positive regulation of pinocytosis+++GO:0044257///cellular protein catabolic process+++GO:0008306///associative learning+++GO:0008344///adult locomotory behavior+++GO:0031579///membrane raft organization+++GO:0007163///establishment or maintenance of cell polarity+++GO:0030308///negative regulation of cell growth+++GO:0043066///negative regulation of apoptotic process","IPR028415///Adenylyl cyclase-associated protein CAP1+++IPR001837///Adenylate cyclase-associated CAP+++IPR013992///Adenylate cyclase-associated CAP, N-terminal+++IPR017901///C-CAP/cofactor C-like domain+++IPR036222///Adenylate cyclase-associated CAP, N-terminal  domain superfamily+++IPR016098///Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal+++IPR028417///CAP, conserved site, C-terminal+++IPR036223///Adenylate cyclase-associated CAP, C-terminal  superfamily+++IPR018106///CAP, conserved site, N-terminal+++IPR013912///Adenylate cyclase-associated CAP, C-terminal+++IPR006599///CARP motif","[CAP1_HUMAN|Reviewed]RecName: Full=Adenylyl cyclase-associated protein 1; Short=CAP 1;+++[D3DPU2_HUMAN|Unreviewed]RecName: Full=Adenylyl cyclase-associated protein {ECO:0000256|RuleBase:RU000647};+++[L8EAI0_HUMAN|Unreviewed]SubName: Full=Alternative protein CAP1 {ECO:0000313|EMBL:CCQ43353.1};+++[Q5T0R1_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413656}; Flags: Fragment;+++[Q5T0R2_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408561}; Flags: Fragment;+++[Q5T0R3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000403198}; Flags: Fragment;+++[Q5T0R4_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000413383}; Flags: Fragment;+++[Q5T0R5_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000410586}; Flags: Fragment;+++[Q5T0R6_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000400943}; Flags: Fragment;+++[Q5T0R7_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398475}; Flags: Fragment;+++[Q5T0R8_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000389974}; Flags: Fragment;+++[Q5T0R9_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000412859}; Flags: Fragment;+++[Q5T0S3_HUMAN|Unreviewed]SubName: Full=Adenylyl cyclase-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398877}; Flags: Fragment;"]
[10488,"'CREB3'",2339,1830,2084.5,"04931///Insulin resistance+++04152///AMPK signaling pathway+++05163///Human cytomegalovirus infection+++04668///TNF signaling pathway+++04714///Thermogenesis+++04261///Adrenergic signaling in cardiomyocytes+++04728///Dopaminergic synapse+++04922///Glucagon signaling pathway+++04911///Insulin secretion+++04962///Vasopressin-regulated water reabsorption+++05215///Prostate cancer+++05034///Alcoholism+++05030///Cocaine addiction+++04928///Parathyroid hormone synthesis, secretion and action+++05031///Amphetamine addiction+++04024///cAMP signaling pathway+++04926///Relaxin signaling pathway+++04725///Cholinergic synapse+++04927///Cortisol synthesis and secretion+++05016///Huntington's disease+++05203///Viral carcinogenesis+++04925///Aldosterone synthesis and secretion+++04022///cGMP-PKG signaling pathway+++04915///Estrogen signaling pathway+++04918///Thyroid hormone synthesis+++04211///Longevity regulating pathway+++05165///Human papillomavirus infection+++04934///Cushing's syndrome+++05161///Hepatitis B+++04916///Melanogenesis+++04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0005634///nucleus+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0043025///neuronal cell body+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0008140///cAMP response element binding protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0035497///cAMP response element binding+++GO:0003682///chromatin binding+++GO:0031726///CCR1 chemokine receptor binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000982///transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0019043///establishment of viral latency+++GO:0001558///regulation of cell growth+++GO:0034976///response to endoplasmic reticulum stress+++GO:0051928///positive regulation of calcium ion transport+++GO:0042981///regulation of apoptotic process+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:0090045///positive regulation of deacetylase activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000326///negative regulation of nuclear receptor transcription coactivator activity+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0006990///positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0030335///positive regulation of cell migration+++GO:0006351///transcription, DNA-templated+++GO:0019046///release from viral latency+++GO:0016032///viral process+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0002230///positive regulation of defense response to virus by host+++GO:0006935///chemotaxis+++GO:0050930///induction of positive chemotaxis","IPR029808///cAMP-responsive element-binding protein 3+++IPR004827///Basic-leucine zipper domain","[CREB3_HUMAN|Reviewed]RecName: Full=Cyclic AMP-responsive element-binding protein 3; Short=CREB-3; Short=cAMP-responsive element-binding protein 3; AltName: Full=Leucine zipper protein; AltName: Full=Luman; AltName: Full=Transcription factor LZIP-alpha; Contains: RecName: Full=Processed cyclic AMP-responsive element-binding protein 3; Short=N-terminal Luman; Short=Transcriptionally active form;"]
[10489,"'LRRC41'",1843,1575,1709,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity","GO:0043687///post-translational protein modification+++GO:0016567///protein ubiquitination","IPR026137///Leucine-rich repeat-containing  41+++IPR032675///Leucine-rich repeat domain superfamily","[LRC41_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 41; AltName: Full=Protein Muf1;+++[A0A087WTI9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000477909}; Flags: Fragment;+++[A0A087WTU1_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000478135};+++[A0A087X0S7_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000483633};+++[A0A0B4J2G4_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484752};+++[A0A0C4DH00_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat-containing protein 41 {ECO:0000313|Ensembl:ENSP00000484558};+++[Q562F1_HUMAN|Unreviewed]SubName: Full=LRRC41 protein {ECO:0000313|EMBL:AAH92479.1}; Flags: Fragment;"]
[10490,"'VTI1B'",717,512,614.5,"04138///Autophagy - yeast+++04130///SNARE interactions in vesicular transport","H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H00186///Hyperargininemia","M00029///Urea cycle+++M00134///Polyamine biosynthesis, arginine => ornithine => putrescine","R00551///L-Arginine amidinohydrolase L-Arginine + H2O <=> L-Ornithine + Urea","GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0031093///platelet alpha granule lumen+++GO:0005829///cytosol+++GO:0031982///vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0055038///recycling endosome membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0043025///neuronal cell body+++GO:0005768///endosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0055037///recycling endosome+++GO:0005764///lysosome+++GO:0031901///early endosome membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0031201///SNARE complex+++GO:0005576///extracellular region+++GO:0008021///synaptic vesicle","GO:0005484///SNAP receptor activity+++GO:0019869///chloride channel inhibitor activity+++GO:0005515///protein binding+++GO:0000149///SNARE binding","GO:0006891///intra-Golgi vesicle-mediated transport+++GO:0002576///platelet degranulation+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006623///protein targeting to vacuole+++GO:0006896///Golgi to vacuole transport+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0008283///cell proliferation+++GO:0016192///vesicle-mediated transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0061025///membrane fusion+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0097352///autophagosome maturation","IPR038407///Vesicle transport v-SNARE, N-terminal domain superfamily+++IPR000727///Target SNARE coiled-coil homology domain+++IPR007705///Vesicle transport v-SNARE, N-terminal+++IPR010989///SNARE","[VTI1B_HUMAN|Reviewed]RecName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B; AltName: Full=Vesicle transport v-SNARE protein Vti1-like 1; AltName: Full=Vti1-rp1;+++[G3V5I2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000452366};+++[H0YJJ5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451661}; Flags: Fragment;+++[H0YJL5_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000451759}; Flags: Fragment;+++[J3KMW2_HUMAN|Unreviewed]SubName: Full=Vesicle transport through interaction with t-SNAREs homolog 1B {ECO:0000313|Ensembl:ENSP00000216456};"]
[104909134,"'LINC02210-CRHR1'",27,42,34.5,{"$nulls":4},"GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0031226///intrinsic component of plasma membrane","GO:0015056///corticotrophin-releasing factor receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0051458///corticotropin secretion+++GO:0071376///cellular response to corticotropin-releasing hormone stimulus+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:2000852///regulation of corticosterone secretion","IPR000832///GPCR, family 2, secretin-like+++IPR003052///GPCR, family 2, corticotropin releasing factor receptor, type 1+++IPR036445///GPCR family 2, extracellular hormone receptor domain superfamily+++IPR017981///GPCR, family 2-like+++IPR017983///GPCR, family 2, secretin-like, conserved site+++IPR001879///GPCR, family 2, extracellular hormone receptor domain+++IPR003051///GPCR, family 2, corticotropin releasing factor receptor","[CRFR1_HUMAN|Reviewed]RecName: Full=Corticotropin-releasing factor receptor 1; Short=CRF-R-1; Short=CRF-R1; Short=CRFR-1; AltName: Full=Corticotropin-releasing hormone receptor 1; Short=CRH-R-1; Short=CRH-R1; Flags: Precursor;+++[A0A024R9X9_HUMAN|Unreviewed]SubName: Full=Corticotropin releasing hormone receptor 1, isoform CRA_b {ECO:0000313|EMBL:EAW93558.1};+++[B4DMR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60308, highly similar to Corticotropin-releasing factor receptor 1 {ECO:0000313|EMBL:BAG59977.1};"]
[10491,"'CRTAP'",5953.01,6037,5995.005,null,"H00506///Osteogenesis imperfecta",null,null,"GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0050821///protein stabilization+++GO:0007283///spermatogenesis+++GO:0018400///peptidyl-proline hydroxylation to 3-hydroxy-L-proline+++GO:0061077///chaperone-mediated protein folding+++GO:1901874///negative regulation of post-translational protein modification","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR033212///Cartilage-associated protein","[CRTAP_HUMAN|Reviewed]RecName: Full=Cartilage-associated protein; Flags: Precursor;+++[B4DPA3_HUMAN|Unreviewed]SubName: Full=Cartilage associated protein, isoform CRA_a {ECO:0000313|EMBL:EAW64448.1}; SubName: Full=cDNA FLJ55123, highly similar to Cartilage-associated protein {ECO:0000313|EMBL:BAG60515.1};+++[C9JP16_HUMAN|Unreviewed]SubName: Full=Cartilage-associated protein {ECO:0000313|Ensembl:ENSP00000409997};"]
[10492,"'SYNCRIP'",1410,1557,1483.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0097452///GAIT complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0070937///CRD-mediated mRNA stability complex+++GO:1990904///ribonucleoprotein complex+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm","GO:0008143///poly(A) binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0001649///osteoblast differentiation+++GO:0008380///RNA splicing+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0006397///mRNA processing+++GO:0016032///viral process+++GO:0071346///cellular response to interferon-gamma+++GO:0006396///RNA processing+++GO:0000398///mRNA splicing, via spliceosome","IPR035979///RNA-binding domain superfamily+++IPR034544///Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1+++IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR006535///HnRNP R/Q splicing factor+++IPR034548///Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2","[HNRPQ_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein Q; Short=hnRNP Q; AltName: Full=Glycine- and tyrosine-rich RNA-binding protein; Short=GRY-RBP; AltName: Full=NS1-associated protein 1; AltName: Full=Synaptotagmin-binding, cytoplasmic RNA-interacting protein;+++[B7Z645_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein, isoform CRA_b {ECO:0000313|EMBL:EAW48623.1}; SubName: Full=cDNA FLJ50849, highly similar to Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|EMBL:BAH13131.1};+++[F6UXX1_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein Q {ECO:0000313|Ensembl:ENSP00000397782}; Flags: Fragment;+++[Q05CK9_HUMAN|Unreviewed]SubName: Full=SYNCRIP protein {ECO:0000313|EMBL:AAH24283.1}; Flags: Fragment;+++[Q59GL1_HUMAN|Unreviewed]SubName: Full=Synaptotagmin binding, cytoplasmic RNA interacting protein variant {ECO:0000313|EMBL:BAD92335.1}; Flags: Fragment;"]
[10493,"'VAT1'",9216,7566,8391,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0035578///azurophil granule lumen+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0070062///extracellular exosome","GO:0008270///zinc ion binding+++GO:0016491///oxidoreductase activity","GO:0010637///negative regulation of mitochondrial fusion+++GO:0060337///type I interferon signaling pathway+++GO:0043312///neutrophil degranulation","IPR020843///Polyketide synthase, enoylreductase domain+++IPR036291///NAD(P)-binding domain superfamily+++IPR002364///Quinone oxidoreductase/zeta-crystallin, conserved site+++IPR013154///Alcohol dehydrogenase, N-terminal+++IPR013149///Alcohol dehydrogenase, C-terminal+++IPR011032///GroES-like superfamily","[VAT1_HUMAN|Reviewed]RecName: Full=Synaptic vesicle membrane protein VAT-1 homolog; EC=1.-.-.-;+++[A0A024R1Z6_HUMAN|Unreviewed]SubName: Full=Vesicle amine transport protein 1 homolog (T californica), isoform CRA_a {ECO:0000313|EMBL:EAW60918.1};+++[K7EJM4_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000465239}; Flags: Fragment;+++[K7EM19_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000466322}; Flags: Fragment;+++[K7ENX2_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000467131}; Flags: Fragment;+++[K7ER81_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468146}; Flags: Fragment;+++[K7ERT7_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468401}; Flags: Fragment;+++[K7ESA3_HUMAN|Unreviewed]SubName: Full=Synaptic vesicle membrane protein VAT-1 homolog {ECO:0000313|Ensembl:ENSP00000468621}; Flags: Fragment;"]
[10494,"'STK25'",2405,2124,2264.5,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding","GO:0023014///signal transduction by protein phosphorylation+++GO:0051683///establishment of Golgi localization+++GO:0006979///response to oxidative stress+++GO:0090168///Golgi reassembly+++GO:0036481///intrinsic apoptotic signaling pathway in response to hydrogen peroxide+++GO:0007165///signal transduction+++GO:0032147///activation of protein kinase activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0006468///protein phosphorylation+++GO:0050772///positive regulation of axonogenesis+++GO:0046777///protein autophosphorylation+++GO:0016310///phosphorylation+++GO:0042542///response to hydrogen peroxide+++GO:0007163///establishment or maintenance of cell polarity+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0051645///Golgi localization","IPR035060///Serine/threonine kinase 25, catalytic domain+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain","[STK25_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 25; EC=2.7.11.1; AltName: Full=Ste20-like kinase; AltName: Full=Sterile 20/oxidant stress-response kinase 1; Short=SOK-1; Short=Ste20/oxidant stress response kinase 1;+++[A0A024R4B2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 (STE20 homolog, yeast), isoform CRA_a {ECO:0000313|EMBL:EAW71266.1}; SubName: Full=Serine/threonine kinase 25 isoform 1 {ECO:0000313|EMBL:ALQ33986.1};+++[A0A0S2Z4Y2_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 3 {ECO:0000313|EMBL:ALQ33988.1}; Flags: Fragment;+++[A0A0S2Z503_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 25 isoform 2 {ECO:0000313|EMBL:ALQ33987.1};+++[B3KRS6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34842 fis, clone NT2NE2011033, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG52488.1};+++[B4DMA5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59346, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG59817.1};+++[B4DVS7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52778, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG62789.1};+++[B4E185_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61527, highly similar to Serine/threonine-protein kinase 25 {ECO:0000313|EMBL:BAG64697.1};+++[C9J232_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000399212}; Flags: Fragment;+++[C9J6L2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000417020}; Flags: Fragment;+++[C9J8E8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000406208}; Flags: Fragment;+++[C9JCC0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403607}; Flags: Fragment;+++[C9JDH9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000395104}; Flags: Fragment;+++[C9JFA1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404552}; Flags: Fragment;+++[C9JIH8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000403866}; Flags: Fragment;+++[C9JJV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404960}; Flags: Fragment;+++[C9JN58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000414191}; Flags: Fragment;+++[C9K0M6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000401114}; Flags: Fragment;+++[E7EM58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000412617}; Flags: Fragment;+++[H7C279_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 25 {ECO:0000313|Ensembl:ENSP00000404469}; Flags: Fragment;+++[Q96BA2_HUMAN|Unreviewed]SubName: Full=STK25 protein {ECO:0000313|EMBL:AAH15793.1};"]
[10495,"'ENOX2'",98,81,89.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region+++GO:0009897///external side of plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0016491///oxidoreductase activity+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0005515///protein binding","GO:0048511///rhythmic process+++GO:0007624///ultradian rhythm+++GO:0055114///oxidation-reduction process+++GO:0040008///regulation of growth","IPR035979///RNA-binding domain superfamily+++IPR034140///Ecto-NOX disulfide-thiol exchanger, RNA recognition motif+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain+++IPR038876///Ecto-NOX disulfide-thiol exchanger","[ENOX2_HUMAN|Reviewed]RecName: Full=Ecto-NOX disulfide-thiol exchanger 2; AltName: Full=APK1 antigen; AltName: Full=Cytosolic ovarian carcinoma antigen 1; AltName: Full=Tumor-associated hydroquinone oxidase; Short=tNOX; Includes: RecName: Full=Hydroquinone [NADH] oxidase; EC=1.-.-.-; Includes: RecName: Full=Protein disulfide-thiol oxidoreductase; EC=1.-.-.-;+++[A0A0C4DGT9_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000478608};+++[A4QPE1_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI39782.2}; Flags: Fragment;+++[B1AKF7_HUMAN|Unreviewed]SubName: Full=Ecto-NOX disulfide-thiol exchanger 2 {ECO:0000313|Ensembl:ENSP00000400304}; Flags: Fragment;+++[Q32ND0_HUMAN|Unreviewed]SubName: Full=ENOX2 protein {ECO:0000313|EMBL:AAI08714.1}; Flags: Fragment;"]
[10497,"'UNC13B'",746,941,843.5,"04721///Synaptic vesicle cycle",{"$nulls":3},"GO:0097470///ribbon synapse+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0042734///presynaptic membrane+++GO:0045202///synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0030672///synaptic vesicle membrane+++GO:0032009///early phagosome+++GO:0048786///presynaptic active zone+++GO:0031594///neuromuscular junction+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0098793///presynapse+++GO:0043195///terminal bouton+++GO:0005794///Golgi apparatus+++GO:0044305///calyx of Held+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol","GO:0019992///diacylglycerol binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017075///syntaxin-1 binding+++GO:0017137///Rab GTPase binding+++GO:0030742///GTP-dependent protein binding+++GO:0005516///calmodulin binding+++GO:0005509///calcium ion binding+++GO:0005543///phospholipid binding","GO:0016082///synaptic vesicle priming+++GO:0016188///synaptic vesicle maturation+++GO:0006887///exocytosis+++GO:0010808///positive regulation of synaptic vesicle priming+++GO:1900426///positive regulation of defense response to bacterium+++GO:0007268///chemical synaptic transmission+++GO:0050714///positive regulation of protein secretion+++GO:0035556///intracellular signal transduction+++GO:0016081///synaptic vesicle docking+++GO:0048172///regulation of short-term neuronal synaptic plasticity+++GO:0061789///dense core granule priming+++GO:0097151///positive regulation of inhibitory postsynaptic potential+++GO:0043065///positive regulation of apoptotic process+++GO:0060384///innervation+++GO:0099525///presynaptic dense core vesicle exocytosis+++GO:0007528///neuromuscular junction development+++GO:0035249///synaptic transmission, glutamatergic+++GO:0090382///phagosome maturation+++GO:0071333///cellular response to glucose stimulus+++GO:0016079///synaptic vesicle exocytosis+++GO:0031914///negative regulation of synaptic plasticity","IPR000008///C2 domain+++IPR037302///Protein Unc-13, C2B domain+++IPR010439///Calcium-dependent secretion activator domain+++IPR014772///Mammalian uncoordinated homology 13, domain 2+++IPR019558///Mammalian uncoordinated homology 13, subgroup, domain 2+++IPR014770///Munc13 homology 1+++IPR035892///C2 domain superfamily+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR027080///Protein Unc-13","[UN13B_HUMAN|Reviewed]RecName: Full=Protein unc-13 homolog B; AltName: Full=Munc13-2; Short=munc13;+++[A0A0U1RRB5_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489441}; Flags: Fragment;+++[A0A0U1RRL2_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000489581};+++[A0A1B0GUS7_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490228};+++[A0A1B0GVW8_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000490683};+++[B1AM27_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000380006};+++[F8W8M9_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000367757};+++[I6L9J0_HUMAN|Unreviewed]SubName: Full=Protein unc-13 homolog B {ECO:0000313|Ensembl:ENSP00000484432}; SubName: Full=UNC13B protein {ECO:0000313|EMBL:AAI11801.1};+++[Q4LE73_HUMAN|Unreviewed]SubName: Full=UNC13B variant protein {ECO:0000313|EMBL:BAE06080.1}; Flags: Fragment;"]
[10498,"'CARM1'",2101,1972,2036.5,"01522///Endocrine resistance",null,null,"R11217///S-adenosyl-L-methionine:[protein]-N(omega)-methyl-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   S-Adenosyl-L-methionine + Protein N(omega)-methyl-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11219///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase ([protein]-N(omega),N(omega)-dimethyl-L-arginine-forming)   2 S-Adenosyl-L-methionine + Protein-L-arginine <=> 2 S-Adenosyl-L-homocysteine + Protein N(omega),N(omega)-dimethyl-L-arginine+++R11216///S-adenosyl-L-methionine:[protein]-L-arginine N-methyltransferase   S-Adenosyl-L-methionine + Protein-L-arginine <=> S-Adenosyl-L-homocysteine + Protein N(omega)-methyl-L-arginine","GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0030374///nuclear receptor transcription coactivator activity+++GO:0008276///protein methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008469///histone-arginine N-methyltransferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0042054///histone methyltransferase activity+++GO:0035642///histone methyltransferase activity (H3-R17 specific)+++GO:0042803///protein homodimerization activity+++GO:0070577///lysine-acetylated histone binding+++GO:0008013///beta-catenin binding+++GO:0035242///protein-arginine omega-N asymmetric methyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0016274///protein-arginine N-methyltransferase activity","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0016571///histone methylation+++GO:0071168///protein localization to chromatin+++GO:0019216///regulation of lipid metabolic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006479///protein methylation+++GO:0032259///methylation+++GO:0034971///histone H3-R17 methylation+++GO:0060350///endochondral bone morphogenesis+++GO:0019919///peptidyl-arginine methylation, to asymmetrical-dimethyl arginine+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0016032///viral process+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0051591///response to cAMP+++GO:1902415///regulation of mRNA binding+++GO:0034970///histone H3-R2 methylation+++GO:0003420///regulation of growth plate cartilage chondrocyte proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0006325///chromatin organization+++GO:0007568///aging+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:2000171///negative regulation of dendrite development+++GO:0032091///negative regulation of protein binding+++GO:0034969///histone arginine methylation","IPR029063///S-adenosyl-L-methionine-dependent methyltransferase+++IPR025799///Protein arginine N-methyltransferase+++IPR011993///PH-like domain superfamily+++IPR020989///Histone-arginine methyltransferase CARM1, N-terminal","[CARM1_HUMAN|Reviewed]RecName: Full=Histone-arginine methyltransferase CARM1; EC=2.1.1.319 {ECO:0000269|PubMed:19405910}; AltName: Full=Coactivator-associated arginine methyltransferase 1; AltName: Full=Protein arginine N-methyltransferase 4;+++[K7EIQ8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000464852}; Flags: Fragment;+++[K7EK20_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000465417}; Flags: Fragment;+++[K7EPK1_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467420};+++[K7EQA8_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467746}; Flags: Fragment;+++[K7EQB9_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000467761}; Flags: Fragment;+++[K7ERM3_HUMAN|Unreviewed]SubName: Full=Histone-arginine methyltransferase CARM1 {ECO:0000313|Ensembl:ENSP00000468319}; Flags: Fragment;"]
[10499,"'NCOA2'",199,433,316,"04915///Estrogen signaling pathway+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding+++GO:0030375///thyroid hormone receptor coactivator activity+++GO:0005102///signaling receptor binding+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0019904///protein domain specific binding+++GO:0001162///RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding+++GO:0035257///nuclear hormone receptor binding+++GO:0016922///nuclear receptor binding+++GO:0003713///transcription coactivator activity","GO:0048511///rhythmic process+++GO:0032570///response to progesterone+++GO:0015721///bile acid and bile salt transport+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010906///regulation of glucose metabolic process+++GO:0007623///circadian rhythm+++GO:0032870///cellular response to hormone stimulus+++GO:0045475///locomotor rhythm+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0032922///circadian regulation of gene expression+++GO:1904017///cellular response to Thyroglobulin triiodothyronine+++GO:0019216///regulation of lipid metabolic process+++GO:0010468///regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR014920///Nuclear receptor coactivator, Ncoa-type, interlocking+++IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR028822///Nuclear receptor coactivator 2+++IPR009110///Nuclear receptor coactivator, interlocking+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain+++IPR000014///PAS domain+++IPR032565///Domain of unknown function DUF4927+++IPR035965///PAS domain superfamily+++IPR013767///PAS fold+++IPR014935///Nuclear receptor coactivator, receptor-binding domain+++IPR037077///Nuclear receptor coactivator, Ncoa-type, interlocking domain superfamily+++IPR017426///Nuclear receptor coactivator+++IPR010011///Domain of unknown function DUF1518","[NCOA2_HUMAN|Reviewed]RecName: Full=Nuclear receptor coactivator 2; Short=NCoA-2; AltName: Full=Class E basic helix-loop-helix protein 75; Short=bHLHe75; AltName: Full=Transcriptional intermediary factor 2; Short=hTIF2;+++[A0A0B6XJZ8_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|EMBL:CEF49517.1}; Flags: Fragment;+++[A0A1D5RMT0_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430850}; Flags: Fragment;+++[B4DPW8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51272, highly similar to Nuclear receptor coactivator 2 {ECO:0000313|EMBL:BAG60730.1};+++[E5RFN9_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430348}; Flags: Fragment;+++[E7EWM1_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000430148};+++[H0YBB6_HUMAN|Unreviewed]SubName: Full=Nuclear receptor coactivator 2 {ECO:0000313|Ensembl:ENSP00000429132}; Flags: Fragment;+++[Q569J4_HUMAN|Unreviewed]SubName: Full=NCOA2 protein {ECO:0000313|EMBL:AAH92442.1};"]
[1050,"'CEBPA'",20,10,15,"05221///Acute myeloid leukemia+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05202///Transcriptional misregulation in cancer+++05200///Pathways in cancer","H00003///Acute myeloid leukemia (AML)",null,null,"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001013///RNA polymerase I regulatory region DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity","GO:0001892///embryonic placenta development+++GO:0008285///negative regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0030225///macrophage differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006351///transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0016032///viral process+++GO:0030851///granulocyte differentiation+++GO:0050873///brown fat cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071285///cellular response to lithium ion+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0043032///positive regulation of macrophage activation+++GO:0055088///lipid homeostasis+++GO:0030324///lung development+++GO:0071356///cellular response to tumor necrosis factor+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0045786///negative regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0045444///fat cell differentiation+++GO:0001889///liver development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000050///urea cycle+++GO:0030099///myeloid cell differentiation+++GO:0008203///cholesterol metabolic process+++GO:0007005///mitochondrion organization+++GO:0048839///inner ear development+++GO:0050872///white fat cell differentiation+++GO:0071407///cellular response to organic cyclic compound+++GO:0048469///cell maturation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006091///generation of precursor metabolites and energy+++GO:0007219///Notch signaling pathway+++GO:0042593///glucose homeostasis+++GO:0006360///transcription by RNA polymerase I","IPR016468///CCAAT/enhancer-binding protein, chordates+++IPR004827///Basic-leucine zipper domain","[CEBPA_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein alpha {ECO:0000312|HGNC:HGNC:1833}; Short=C/EBP alpha {ECO:0000312|HGNC:HGNC:1833};"]
[10500,"'SEMA6C'",144,165,154.5,"04360///Axon guidance",{"$nulls":3},"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface","GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0001755///neural crest cell migration+++GO:0030335///positive regulation of cell migration+++GO:0050919///negative chemotaxis+++GO:0007399///nervous system development+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0007411///axon guidance+++GO:0030517///negative regulation of axon extension+++GO:0030154///cell differentiation+++GO:0048843///negative regulation of axon extension involved in axon guidance","IPR027231///Semaphorin+++IPR001627///Sema domain+++IPR036352///Sema domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR015514///Semaphorin 6C","[SEM6C_HUMAN|Reviewed]RecName: Full=Semaphorin-6C; AltName: Full=Semaphorin-Y; Short=Sema Y; Flags: Precursor;+++[A0A087WYX3_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000482163};+++[A0A087X0A5_HUMAN|Unreviewed]SubName: Full=Semaphorin-6C {ECO:0000313|Ensembl:ENSP00000483227};+++[Q1RMY5_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14624.1};+++[Q24JR3_HUMAN|Unreviewed]SubName: Full=SEMA6C protein {ECO:0000313|EMBL:AAI14522.1};"]
[10501,"'SEMA6B'",311,302,306.5,"04360///Axon guidance",{"$nulls":3},"GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0030335///positive regulation of cell migration+++GO:0030154///cell differentiation+++GO:0007399///nervous system development","IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR002165///Plexin repeat+++IPR001627///Sema domain+++IPR036352///Sema domain superfamily+++IPR027231///Semaphorin","[SEM6B_HUMAN|Reviewed]RecName: Full=Semaphorin-6B; AltName: Full=Semaphorin-Z; Short=Sema Z; Flags: Precursor;+++[Q9BXR8_HUMAN|Unreviewed]SubName: Full=Semaphorin 6B isoform 2 {ECO:0000313|EMBL:AAK16831.1};"]
[10505,"'SEMA4F'",514.73,549.24,531.985,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005615///extracellular space+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0031290///retinal ganglion cell axon guidance+++GO:0030154///cell differentiation+++GO:0007267///cell-cell signaling+++GO:0007275///multicellular organism development+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension+++GO:0001755///neural crest cell migration+++GO:0007411///axon guidance+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis","IPR015512///Semaphorin 4F+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR002165///Plexin repeat+++IPR016201///PSI domain+++IPR001627///Sema domain+++IPR027231///Semaphorin+++IPR036352///Sema domain superfamily","[SEM4F_HUMAN|Reviewed]RecName: Full=Semaphorin-4F; AltName: Full=Semaphorin-M; Short=Sema M; AltName: Full=Semaphorin-W; Short=Sema W; Flags: Precursor;+++[A0A087WYZ7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000482238};+++[B7Z931_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52836, highly similar to Semaphorin-4F {ECO:0000313|EMBL:BAH14167.1};+++[C9JKW7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000409141}; Flags: Fragment;+++[C9K0A1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000407698}; Flags: Fragment;+++[F8WCP8_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000416490};+++[F8WD61_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000396703};+++[F8WEH3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4F {ECO:0000313|Ensembl:ENSP00000413882};"]
[10507,"'SEMA4D'",114.14,126.26,120.2,"04360///Axon guidance","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0038023///signaling receptor activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0004888///transmembrane signaling receptor activity","GO:0008360///regulation of cell shape+++GO:0030335///positive regulation of cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0050919///negative chemotaxis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0050772///positive regulation of axonogenesis+++GO:0007275///multicellular organism development+++GO:0006955///immune response+++GO:0048814///regulation of dendrite morphogenesis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:1900220///semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis+++GO:0048672///positive regulation of collateral sprouting+++GO:0070486///leukocyte aggregation+++GO:0010693///negative regulation of alkaline phosphatase activity+++GO:0043931///ossification involved in bone maturation+++GO:0050732///negative regulation of peptidyl-tyrosine phosphorylation+++GO:0007155///cell adhesion+++GO:0001755///neural crest cell migration+++GO:0001934///positive regulation of protein phosphorylation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0030154///cell differentiation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007399///nervous system development+++GO:0043547///positive regulation of GTPase activity+++GO:0031344///regulation of cell projection organization+++GO:0045668///negative regulation of osteoblast differentiation","IPR013783///Immunoglobulin-like fold+++IPR001627///Sema domain+++IPR003598///Immunoglobulin subtype 2+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR036352///Sema domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR013151///Immunoglobulin+++IPR003599///Immunoglobulin subtype+++IPR016201///PSI domain+++IPR027231///Semaphorin+++IPR002165///Plexin repeat","[SEM4D_HUMAN|Reviewed]RecName: Full=Semaphorin-4D; AltName: Full=A8; AltName: Full=BB18; AltName: Full=GR3; AltName: CD_antigen=CD100; Flags: Precursor;+++[A0A0C4DG45_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000399948};+++[C9JD54_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000416747}; Flags: Fragment;+++[C9JFP1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000390754}; Flags: Fragment;+++[C9JYS7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000413352}; Flags: Fragment;+++[E9PFD9_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000395222};+++[F5H044_HUMAN|Unreviewed]SubName: Full=Semaphorin-4D {ECO:0000313|Ensembl:ENSP00000438389}; Flags: Fragment;+++[Q4LE41_HUMAN|Unreviewed]SubName: Full=SEMA4D variant protein {ECO:0000313|EMBL:BAE06112.1}; Flags: Fragment;"]
[10509,"'SEMA4B'",358,400,379,"04360///Axon guidance","H00527///Retinitis pigmentosa (RP)+++H00481///Cone-rod dystrophy and cone dystrophy",null,null,"GO:0005615///extracellular space+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0030335///positive regulation of cell migration+++GO:0007275///multicellular organism development+++GO:0001755///neural crest cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0007399///nervous system development+++GO:0050919///negative chemotaxis+++GO:0030154///cell differentiation+++GO:0071526///semaphorin-plexin signaling pathway","IPR002165///Plexin repeat+++IPR016201///PSI domain+++IPR036352///Sema domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR027231///Semaphorin+++IPR001627///Sema domain","[SEM4B_HUMAN|Reviewed]RecName: Full=Semaphorin-4B; Flags: Precursor;+++[H0YKV7_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000452957};+++[H0YLN3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453272}; Flags: Fragment;+++[H0YM68_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453484};+++[H0YMD6_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453563}; Flags: Fragment;+++[H0YMR1_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453705}; Flags: Fragment;+++[H0YMZ3_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453804}; Flags: Fragment;+++[H0YN49_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453866}; Flags: Fragment;+++[H0YNC4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000453951}; Flags: Fragment;+++[H0YNM2_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000454068}; Flags: Fragment;+++[J3KNP4_HUMAN|Unreviewed]SubName: Full=Semaphorin-4B {ECO:0000313|Ensembl:ENSP00000332204};+++[Q4VBY2_HUMAN|Unreviewed]SubName: Full=SEMA4B protein {ECO:0000313|EMBL:AAH94849.1}; Flags: Fragment;"]
[1051,"'CEBPB'",1222,925,1073.5,"05152///Tuberculosis+++04668///TNF signaling pathway+++05202///Transcriptional misregulation in cancer+++04657///IL-17 signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0036488///CHOP-C/EBP complex+++GO:0000779///condensed chromosome, centromeric region+++GO:0000790///nuclear chromatin+++GO:0016363///nuclear matrix+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0035259///glucocorticoid receptor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0003682///chromatin binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0042826///histone deacetylase binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0019900///kinase binding+++GO:0046982///protein heterodimerization activity","GO:0006955///immune response+++GO:0045444///fat cell differentiation+++GO:0050729///positive regulation of inflammatory response+++GO:0071222///cellular response to lipopolysaccharide+++GO:1901329///regulation of odontoblast differentiation+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0042742///defense response to bacterium+++GO:0045408///regulation of interleukin-6 biosynthetic process+++GO:0035711///T-helper 1 cell activation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0070169///positive regulation of biomineral tissue development+++GO:0032753///positive regulation of interleukin-4 production+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0006953///acute-phase response+++GO:0006954///inflammatory response+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001541///ovarian follicle development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0071347///cellular response to interleukin-1+++GO:0001889///liver development+++GO:0042130///negative regulation of T cell proliferation+++GO:0034976///response to endoplasmic reticulum stress+++GO:2000120///positive regulation of sodium-dependent phosphate transport+++GO:0007613///memory+++GO:0071407///cellular response to organic cyclic compound+++GO:0071230///cellular response to amino acid stimulus+++GO:0001892///embryonic placenta development+++GO:0006366///transcription by RNA polymerase II+++GO:0002432///granuloma formation+++GO:0050873///brown fat cell differentiation+++GO:0097421///liver regeneration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1990440///positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:0045600///positive regulation of fat cell differentiation+++GO:0030182///neuron differentiation+++GO:0072574///hepatocyte proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045670///regulation of osteoclast differentiation+++GO:0030154///cell differentiation+++GO:0032496///response to lipopolysaccharide+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0060850///regulation of transcription involved in cell fate commitment+++GO:2001198///regulation of dendritic cell differentiation","IPR016468///CCAAT/enhancer-binding protein, chordates+++IPR004827///Basic-leucine zipper domain","[CEBPB_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein beta {ECO:0000312|HGNC:HGNC:1834}; Short=C/EBP beta {ECO:0000312|HGNC:HGNC:1834}; AltName: Full=Liver activator protein; Short=LAP; AltName: Full=Liver-enriched inhibitory protein; Short=LIP; AltName: Full=Nuclear factor NF-IL6 {ECO:0000303|PubMed:1741402}; AltName: Full=Transcription factor 5; Short=TCF-5;+++[Q9BSC0_HUMAN|Unreviewed]SubName: Full=CEBPB protein {ECO:0000313|EMBL:AAH05132.2}; Flags: Fragment;+++[W8SNU6_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26745.1}; Flags: Fragment;+++[W8SNV5_HUMAN|Unreviewed]SubName: Full=Transcription factor C/EBP beta {ECO:0000313|EMBL:AHM26755.1}; Flags: Fragment;"]
[10512,"'SEMA3C'",5265,6996,6130.5,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0050919///negative chemotaxis+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0003350///pulmonary myocardium development+++GO:0006955///immune response+++GO:0060174///limb bud formation+++GO:0140074///cardiac endothelial to mesenchymal transition+++GO:0001755///neural crest cell migration+++GO:0007507///heart development+++GO:0042493///response to drug+++GO:0030154///cell differentiation+++GO:0009791///post-embryonic development+++GO:0001756///somitogenesis+++GO:0007275///multicellular organism development+++GO:0021915///neural tube development+++GO:0003148///outflow tract septum morphogenesis+++GO:0007399///nervous system development+++GO:0001974///blood vessel remodeling+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0003151///outflow tract morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0007411///axon guidance+++GO:1905312///positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis+++GO:0060666///dichotomous subdivision of terminal units involved in salivary gland branching","IPR001627///Sema domain+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003599///Immunoglobulin subtype+++IPR013098///Immunoglobulin I-set+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR027231///Semaphorin+++IPR016201///PSI domain+++IPR036352///Sema domain superfamily","[SEM3C_HUMAN|Reviewed]RecName: Full=Semaphorin-3C; AltName: Full=Semaphorin-E; Short=Sema E; Flags: Precursor;+++[F2Z2Y0_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000395398};+++[F8WEP9_HUMAN|Unreviewed]SubName: Full=Semaphorin-3C {ECO:0000313|Ensembl:ENSP00000393825};+++[Q75L25_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS07489.1}; Flags: Fragment;+++[Q75MX0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEMA3C {ECO:0000313|EMBL:AAS00351.1}; Flags: Fragment;"]
[10513,"'APPBP2'",402.95,535,468.975,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005875///microtubule associated complex+++GO:0005874///microtubule+++GO:0005634///nucleus","GO:0003777///microtubule motor activity+++GO:0005515///protein binding","GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0046907///intracellular transport","IPR013026///Tetratricopeptide repeat-containing domain+++IPR019734///Tetratricopeptide repeat+++IPR011990///Tetratricopeptide-like helical domain superfamily","[APBP2_HUMAN|Reviewed]RecName: Full=Amyloid protein-binding protein 2; AltName: Full=Amyloid beta precursor protein-binding protein 2; Short=APP-BP2; AltName: Full=Protein interacting with APP tail 1;+++[A0A024QZ47_HUMAN|Unreviewed]SubName: Full=Amyloid beta protein (Cytoplasmic tail) binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW51407.1};+++[K7EIZ9_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000464962}; Flags: Fragment;+++[K7EN61_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000466802};+++[K7ENN3_HUMAN|Unreviewed]SubName: Full=Amyloid protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000467025};"]
[10514,"'MYBBP1A'",1663,1798,1730.5,{"$nulls":4},"GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0042564///NLS-dependent protein nuclear import complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle","GO:0043565///sequence-specific DNA binding+++GO:0070888///E-box binding+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0003714///transcription corepressor activity","GO:2000210///positive regulation of anoikis+++GO:0042254///ribosome biogenesis+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0001649///osteoblast differentiation+++GO:0071158///positive regulation of cell cycle arrest+++GO:0032922///circadian regulation of gene expression+++GO:0022904///respiratory electron transport chain+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0048511///rhythmic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042149///cellular response to glucose starvation+++GO:0045815///positive regulation of gene expression, epigenetic","IPR007015///DNA polymerase V/Myb-binding protein 1A+++IPR016024///Armadillo-type fold","[MBB1A_HUMAN|Reviewed]RecName: Full=Myb-binding protein 1A;+++[I3L1L3_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000458919}; Flags: Fragment;+++[I3L2H8_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000459692}; Flags: Fragment;+++[I3L311_HUMAN|Unreviewed]SubName: Full=Myb-binding protein 1A {ECO:0000313|Ensembl:ENSP00000460087}; Flags: Fragment;"]
[10516,"'FBLN5'",1279,1020,1149.5,null,"H00821///Age-related macular degeneration+++H00557///Cutis laxa",null,null,"GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:0031012///extracellular matrix+++GO:0071953///elastic fiber+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space","GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0008022///protein C-terminus binding+++GO:0042803///protein homodimerization activity+++GO:0030023///extracellular matrix constituent conferring elasticity+++GO:0005509///calcium ion binding","GO:2000121///regulation of removal of superoxide radicals+++GO:0048251///elastic fiber assembly+++GO:0030198///extracellular matrix organization+++GO:0034394///protein localization to cell surface+++GO:0007160///cell-matrix adhesion+++GO:0007155///cell adhesion+++GO:0001558///regulation of cell growth+++GO:0046903///secretion","IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR037288///Fibulin-5+++IPR026823///Complement Clr-like EGF domain+++IPR001881///EGF-like calcium-binding domain+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR013032///EGF-like, conserved site+++IPR000742///EGF-like domain+++IPR018097///EGF-like calcium-binding, conserved site+++IPR037287///Fibulin 3/4/5","[FBLN5_HUMAN|Reviewed]RecName: Full=Fibulin-5; Short=FIBL-5; AltName: Full=Developmental arteries and neural crest EGF-like protein; Short=Dance; AltName: Full=Urine p50 protein; Short=UP50; Flags: Precursor;+++[A0A024R6G3_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_b {ECO:0000313|EMBL:EAW81467.1}; SubName: Full=Testis tissue sperm-binding protein Li 75n {ECO:0000313|EMBL:AEE61295.1};+++[G3V2P8_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000450787};+++[G3V329_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451002};+++[G3V3Y2_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451486}; Flags: Fragment;+++[G3V4U0_HUMAN|Unreviewed]SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000451982};+++[G3XA98_HUMAN|Unreviewed]SubName: Full=Fibulin 5, isoform CRA_a {ECO:0000313|EMBL:EAW81465.1}; SubName: Full=Fibulin-5 {ECO:0000313|Ensembl:ENSP00000267620};"]
[10517,"'FBXW10'",7.14,2.39,4.765,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0000209///protein polyubiquitination","IPR020472///G-protein beta WD-40 repeat+++IPR001680///WD40 repeat+++IPR017986///WD40-repeat-containing domain+++IPR036047///F-box-like domain superfamily+++IPR019775///WD40 repeat, conserved site+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[FBW10_HUMAN|Reviewed]RecName: Full=F-box/WD repeat-containing protein 10; AltName: Full=F-box and WD-40 domain-containing protein 10; AltName: Full=Ubiquitin ligase-specificity factor;+++[J3QLH9_HUMAN|Unreviewed]SubName: Full=F-box/WD repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000463552};"]
[10518,"'CIB2'",131,85,108,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0042383///sarcolemma+++GO:0005737///cytoplasm+++GO:0032437///cuticular plate+++GO:0005929///cilium+++GO:0005886///plasma membrane+++GO:0005927///muscle tendon junction+++GO:0031594///neuromuscular junction+++GO:0042995///cell projection+++GO:0001750///photoreceptor outer segment+++GO:0016020///membrane+++GO:0072562///blood microparticle+++GO:0032420///stereocilium+++GO:0001917///photoreceptor inner segment","GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0000287///magnesium ion binding+++GO:0042803///protein homodimerization activity+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding","GO:0071318///cellular response to ATP+++GO:0055074///calcium ion homeostasis+++GO:0045494///photoreceptor cell maintenance+++GO:0007204///positive regulation of cytosolic calcium ion concentration","IPR018247///EF-Hand 1, calcium-binding site+++IPR002048///EF-hand domain+++IPR011992///EF-hand domain pair","[CIB2_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding family member 2; AltName: Full=Kinase-interacting protein 2; Short=KIP 2;+++[A0A2R8Y4Y2_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000494155}; Flags: Fragment;+++[H0YKC8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452752};+++[H0YKX8_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000452980}; Flags: Fragment;+++[H0YLL7_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453256}; Flags: Fragment;+++[H0YLX3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453377}; Flags: Fragment;+++[H0YML3_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453654}; Flags: Fragment;+++[H0YND4_HUMAN|Unreviewed]SubName: Full=Calcium and integrin-binding family member 2 {ECO:0000313|Ensembl:ENSP00000453963};"]
[10519,"'CIB1'",1058,879,968.5,"04137///Mitophagy - animal+++04360///Axon guidance+++04140///Autophagy - animal","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0016324///apical plasma membrane+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0032433///filopodium tip+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0031982///vesicle+++GO:0030424///axon+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030426///growth cone+++GO:0005815///microtubule organizing center+++GO:0030027///lamellipodium+++GO:0030425///dendrite+++GO:0042383///sarcolemma+++GO:0032587///ruffle membrane+++GO:0043025///neuronal cell body+++GO:0071944///cell periphery","GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0017016///Ras GTPase binding+++GO:0005509///calcium ion binding+++GO:0044325///ion channel binding+++GO:0043495///protein membrane anchor+++GO:0008427///calcium-dependent protein kinase inhibitor activity+++GO:0008022///protein C-terminus binding+++GO:0019901///protein kinase binding","GO:0045653///negative regulation of megakaryocyte differentiation+++GO:0071363///cellular response to growth factor stimulus+++GO:0010977///negative regulation of neuron projection development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0007155///cell adhesion+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0042127///regulation of cell proliferation+++GO:0001525///angiogenesis+++GO:0007286///spermatid development+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:2000256///positive regulation of male germ cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0001934///positive regulation of protein phosphorylation+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0051301///cell division+++GO:0030307///positive regulation of cell growth+++GO:0030220///platelet formation+++GO:0033630///positive regulation of cell adhesion mediated by integrin+++GO:0002931///response to ischemia+++GO:0031122///cytoplasmic microtubule organization+++GO:0008285///negative regulation of cell proliferation+++GO:0006469///negative regulation of protein kinase activity+++GO:0007113///endomitotic cell cycle+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0071356///cellular response to tumor necrosis factor+++GO:0038163///thrombopoietin-mediated signaling pathway+++GO:0006302///double-strand break repair+++GO:0007049///cell cycle+++GO:0001933///negative regulation of protein phosphorylation+++GO:0043085///positive regulation of catalytic activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0071901///negative regulation of protein serine/threonine kinase activity+++GO:0051302///regulation of cell division+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0030154///cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0008284///positive regulation of cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0001954///positive regulation of cell-matrix adhesion+++GO:0006915///apoptotic process+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007283///spermatogenesis","IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain","[CIB1_HUMAN|Reviewed]RecName: Full=Calcium and integrin-binding protein 1; Short=CIB; AltName: Full=Calcium- and integrin-binding protein; Short=CIBP; AltName: Full=Calmyrin; AltName: Full=DNA-PKcs-interacting protein; AltName: Full=Kinase-interacting protein; Short=KIP; AltName: Full=SNK-interacting protein 2-28; Short=SIP2-28;+++[A0A140VK09_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 9 {ECO:0000313|EMBL:AEE61146.1};"]
[1052,"'CEBPD'",115,85,100,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0019221///cytokine-mediated signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR004827///Basic-leucine zipper domain+++IPR016468///CCAAT/enhancer-binding protein, chordates","[CEBPD_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein delta; Short=C/EBP delta; AltName: Full=Nuclear factor NF-IL6-beta {ECO:0000303|PubMed:1741402}; Short=NF-IL6-beta {ECO:0000303|PubMed:1741402};+++[Q504X4_HUMAN|Unreviewed]SubName: Full=CEBPD protein {ECO:0000313|EMBL:AAH94715.1};"]
[10520,"'ZNF211'",126,118,122,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZN211_HUMAN|Reviewed]RecName: Full=Zinc finger protein 211; AltName: Full=Zinc finger protein C2H2-25;+++[A0A0A0MTK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442601};+++[F5GY70_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000440793};+++[F5H771_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000442740};+++[H0Y3T8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 211 {ECO:0000313|Ensembl:ENSP00000384436}; Flags: Fragment;"]
[10521,"'DDX17'",2041,2695,2368,{"$nulls":4},"GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005730///nucleolus","GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0008186///RNA-dependent ATPase activity+++GO:0003724///RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding","GO:0045445///myoblast differentiation+++GO:0006396///RNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0010586///miRNA metabolic process+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0031047///gene silencing by RNA+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0002376///immune system process+++GO:0030521///androgen receptor signaling pathway+++GO:0001837///epithelial to mesenchymal transition+++GO:0051607///defense response to virus+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006364///rRNA processing+++GO:0006357///regulation of transcription by RNA polymerase II","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001650///Helicase, C-terminal+++IPR000629///ATP-dependent RNA helicase DEAD-box, conserved site+++IPR014014///RNA helicase, DEAD-box type, Q motif+++IPR011545///DEAD/DEAH box helicase domain+++IPR014001///Helicase superfamily 1/2, ATP-binding domain","[DDX17_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX17; EC=3.6.4.13; AltName: Full=DEAD box protein 17; AltName: Full=DEAD box protein p72; AltName: Full=DEAD box protein p82 {ECO:0000303|PubMed:19995069}; AltName: Full=RNA-dependent helicase p72;+++[A0A0U1RQJ0_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000489029}; Flags: Fragment;+++[A0A1W2PQ51_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000491776};+++[A0A1X7SBZ2_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX17 {ECO:0000313|Ensembl:ENSP00000385536};+++[Q59F66_HUMAN|Unreviewed]SubName: Full=DEAD box polypeptide 17 isoform p82 variant {ECO:0000313|EMBL:BAD92832.1}; Flags: Fragment;"]
[10522,"'DEAF1'",1164,781,972.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center+++GO:0005667///transcription factor complex+++GO:0005902///microvillus+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0016605///PML body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0001931///uropod","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0031072///heat shock protein binding+++GO:0046872///metal ion binding+++GO:0030544///Hsp70 protein binding","GO:0007275///multicellular organism development+++GO:0050900///leukocyte migration+++GO:0009653///anatomical structure morphogenesis+++GO:0007162///negative regulation of cell adhesion+++GO:0006935///chemotaxis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0050863///regulation of T cell activation+++GO:0042130///negative regulation of T cell proliferation+++GO:0050901///leukocyte tethering or rolling+++GO:0006955///immune response+++GO:0033599///regulation of mammary gland epithelial cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007399///nervous system development+++GO:0007281///germ cell development+++GO:0001843///neural tube closure+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002296///T-helper 1 cell lineage commitment+++GO:0006366///transcription by RNA polymerase II+++GO:2000406///positive regulation of T cell migration+++GO:0006968///cellular defense response+++GO:0008542///visual learning+++GO:0042742///defense response to bacterium+++GO:0048706///embryonic skeletal system development+++GO:0007163///establishment or maintenance of cell polarity+++GO:2000404///regulation of T cell migration+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0032609///interferon-gamma production+++GO:0042535///positive regulation of tumor necrosis factor biosynthetic process+++GO:0001662///behavioral fear response","IPR024119///Transcription factor DEAF-1+++IPR002893///Zinc finger, MYND-type+++IPR000770///SAND domain+++IPR010919///SAND-like domain superfamily","[DEAF1_HUMAN|Reviewed]RecName: Full=Deformed epidermal autoregulatory factor 1 homolog; AltName: Full=Nuclear DEAF-1-related transcriptional regulator; Short=NUDR; AltName: Full=Suppressin; AltName: Full=Zinc finger MYND domain-containing protein 5;+++[A0A0J9YWD6_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000487909}; Flags: Fragment;+++[A0A0J9YX80_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488285}; Flags: Fragment;+++[A0A0J9YXA4_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000488313}; Flags: Fragment;+++[C9JUK7_HUMAN|Unreviewed]SubName: Full=Leukosialin {ECO:0000313|Ensembl:ENSP00000412907}; Flags: Fragment;+++[H0YCH1_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000431563}; Flags: Fragment;+++[H0YCY2_HUMAN|Unreviewed]SubName: Full=Deformed epidermal autoregulatory factor 1 homolog {ECO:0000313|Ensembl:ENSP00000432518}; Flags: Fragment;"]
[10523,"'CHERP'",1459,1806,1632.5,"03040///Spliceosome",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005623///cell+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0044325///ion channel binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0006874///cellular calcium ion homeostasis+++GO:0007399///nervous system development+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0008285///negative regulation of cell proliferation+++GO:0051209///release of sequestered calcium ion into cytosol","IPR000467///G-patch domain+++IPR039037///Calcium homeostasis endoplasmic reticulum protein+++IPR006903///RNA polymerase II-binding domain+++IPR008942///ENTH/VHS+++IPR000061///SWAP/Surp+++IPR035967///SWAP/Surp superfamily+++IPR006569///CID domain","[CHERP_HUMAN|Reviewed]RecName: Full=Calcium homeostasis endoplasmic reticulum protein; AltName: Full=ERPROT 213-21; AltName: Full=SR-related CTD-associated factor 6;+++[J3QK89_HUMAN|Unreviewed]SubName: Full=Calcium homeostasis endoplasmic reticulum protein {ECO:0000313|Ensembl:ENSP00000198939};"]
[10524,"'KAT5'",645.37,483.01,564.19,"05166///HTLV-I infection","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032777///Piccolo NuA4 histone acetyltransferase complex+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0000123///histone acetyltransferase complex+++GO:0005730///nucleolus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000790///nuclear chromatin+++GO:0035267///NuA4 histone acetyltransferase complex+++GO:0000812///Swr1 complex","GO:0070491///repressing transcription factor binding+++GO:0003713///transcription coactivator activity+++GO:0016740///transferase activity+++GO:0042393///histone binding+++GO:0005515///protein binding+++GO:0010485///H4 histone acetyltransferase activity+++GO:0046872///metal ion binding+++GO:0050681///androgen receptor binding+++GO:0016407///acetyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0004402///histone acetyltransferase activity","GO:0006978///DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1901985///positive regulation of protein acetylation+++GO:0016032///viral process+++GO:0006302///double-strand break repair+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0000729///DNA double-strand break processing+++GO:0016573///histone acetylation+++GO:0040008///regulation of growth+++GO:0032703///negative regulation of interleukin-2 production+++GO:0010212///response to ionizing radiation+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0071392///cellular response to estradiol stimulus+++GO:0006260///DNA replication+++GO:0030521///androgen receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","IPR002717///Histone acetyltransferase domain, MYST-type+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR000953///Chromo/chromo shadow domain+++IPR037995///Histone acetyltransferase Esa1/KAT5/Tip60+++IPR025995///RNA binding activity-knot of a chromodomain+++IPR016197///Chromo-like domain superfamily+++IPR016181///Acyl-CoA N-acyltransferase","[KAT5_HUMAN|Reviewed]RecName: Full=Histone acetyltransferase KAT5; EC=2.3.1.48 {ECO:0000269|PubMed:10096020, ECO:0000269|PubMed:12468530, ECO:0000269|PubMed:29040603}; AltName: Full=60 kDa Tat-interactive protein; Short=Tip60 {ECO:0000303|PubMed:10096020, ECO:0000303|PubMed:11416127, ECO:0000303|PubMed:12801643, ECO:0000303|PubMed:29040603}; AltName: Full=Histone acetyltransferase HTATIP; Short=HIV-1 Tat interactive protein; AltName: Full=Lysine acetyltransferase 5; AltName: Full=cPLA(2)-interacting protein;+++[A0A024R597_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[A0A024R5E8_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PJI1_HUMAN|Unreviewed]RecName: Full=Histone acetyltransferase {ECO:0000256|RuleBase:RU361211}; EC=2.3.1.48 {ECO:0000256|RuleBase:RU361211};+++[E9PMG8_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000434993}; Flags: Fragment;+++[E9PRL6_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436012}; Flags: Fragment;+++[E9PRM3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436000}; Flags: Fragment;+++[E9PRS1_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435939}; Flags: Fragment;+++[H0YEG3_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000435766}; Flags: Fragment;+++[H0YEP0_HUMAN|Unreviewed]SubName: Full=Histone acetyltransferase KAT5 {ECO:0000313|Ensembl:ENSP00000436247}; Flags: Fragment;"]
[10525,"'HYOU1'",5683,6444,6063.5,"04141///Protein processing in endoplasmic reticulum","H00118///Congenital disorders of glycosylation (CDG) type I+++H00770///Congenital myasthenic syndrome","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0016020///membrane+++GO:0071682///endocytic vesicle lumen+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0005790///smooth endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005925///focal adhesion","GO:0051087///chaperone binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0036498///IRE1-mediated unfolded protein response+++GO:0034976///response to endoplasmic reticulum stress+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006898///receptor-mediated endocytosis+++GO:0043066///negative regulation of apoptotic process+++GO:1903382///negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway+++GO:0071456///cellular response to hypoxia+++GO:0002931///response to ischemia+++GO:1903298///negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway","IPR018181///Heat shock protein 70, conserved site+++IPR029047///Heat shock protein 70kD, peptide-binding domain superfamily+++IPR013126///Heat shock protein 70 family+++IPR029048///Heat shock protein 70kD, C-terminal domain superfamily","[HYOU1_HUMAN|Reviewed]RecName: Full=Hypoxia up-regulated protein 1; AltName: Full=150 kDa oxygen-regulated protein; Short=ORP-150; AltName: Full=170 kDa glucose-regulated protein; Short=GRP-170; Flags: Precursor;+++[A0A024R3G0_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated 1, isoform CRA_a {ECO:0000313|EMBL:EAW67441.1};+++[A0A087WW13_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000479845}; Flags: Fragment;+++[A0A087WWI4_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000480248};+++[A0A087X054_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000483106};+++[A0A087X214_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000484622}; Flags: Fragment;+++[B3KXH0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45395 fis, clone BRHIP3027191, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAG54482.1};+++[B7Z602_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59408, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13088.1};+++[B7Z766_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54564, highly similar to 150 kDa oxygen-regulated protein (Orp150) {ECO:0000313|EMBL:BAH13502.1};+++[E9PJ21_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000431874}; Flags: Fragment;+++[J3KSR2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000464026};+++[J3KTF1_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000462951}; Flags: Fragment;+++[J3QL06_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463318}; Flags: Fragment;+++[J3QLE9_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463515}; Flags: Fragment;+++[J3QQH7_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000463742}; Flags: Fragment;+++[K7EQK2_HUMAN|Unreviewed]SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000467866};+++[Q05D91_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH17726.1}; Flags: Fragment;+++[Q6IN67_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH72436.1};+++[Q9BST8_HUMAN|Unreviewed]SubName: Full=HYOU1 protein {ECO:0000313|EMBL:AAH04560.1}; SubName: Full=Hypoxia up-regulated protein 1 {ECO:0000313|Ensembl:ENSP00000482199};"]
[10526,"'IPO8'",343,497,420,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005623///cell+++GO:0005635///nuclear envelope","GO:0008565///protein transporter activity+++GO:0008536///Ran GTPase binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0060964///regulation of gene silencing by miRNA+++GO:0006886///intracellular protein transport+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction","IPR013713///Exportin-2, central domain+++IPR011989///Armadillo-like helical+++IPR001494///Importin-beta, N-terminal domain+++IPR016024///Armadillo-type fold+++IPR005043///Exportin-2, C-terminal","[IPO8_HUMAN|Reviewed]RecName: Full=Importin-8; Short=Imp8; AltName: Full=Ran-binding protein 8; Short=RanBP8;+++[A0A087WXH2_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000481026}; Flags: Fragment;+++[F5GXT5_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000440979}; Flags: Fragment;+++[F5H009_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000444050}; Flags: Fragment;+++[F5H244_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439556}; Flags: Fragment;+++[F5H292_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000439413}; Flags: Fragment;+++[F5H2I3_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446254}; Flags: Fragment;+++[F5H815_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000443789};+++[H0YH64_HUMAN|Unreviewed]SubName: Full=Importin-8 {ECO:0000313|Ensembl:ENSP00000446232}; Flags: Fragment;"]
[10527,"'IPO7'",984,1399,1191.5,"04013///MAPK signaling pathway - fly",{"$nulls":3},"GO:0016020///membrane+++GO:0005623///cell+++GO:0005654///nucleoplasm+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005643///nuclear pore","GO:0008536///Ran GTPase binding+++GO:0008565///protein transporter activity+++GO:0042393///histone binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0030695///GTPase regulator activity","GO:0045087///innate immune response+++GO:0006606///protein import into nucleus+++GO:0007165///signal transduction+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process","IPR001494///Importin-beta, N-terminal domain+++IPR013713///Exportin-2, central domain+++IPR016024///Armadillo-type fold","[IPO7_HUMAN|Reviewed]RecName: Full=Importin-7; Short=Imp7; AltName: Full=Ran-binding protein 7; Short=RanBP7;+++[B3KNG9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14581 fis, clone NT2RM4001382, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51331.1}; SubName: Full=cDNA FLJ14986 fis, clone Y79AA1000784, highly similar to Importin-7 {ECO:0000313|EMBL:BAG51391.1};+++[E9PLB2_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000435235}; Flags: Fragment;+++[E9PLJ0_HUMAN|Unreviewed]SubName: Full=Importin-7 {ECO:0000313|Ensembl:ENSP00000433313};+++[L8E8A9_HUMAN|Unreviewed]SubName: Full=Alternative protein IPO7 {ECO:0000313|EMBL:CCQ43354.1};"]
[10528,"'NOP56'",946,834,890,"03008///Ribosome biogenesis in eukaryotes","H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0031428///box C/D snoRNP complex+++GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0070761///pre-snoRNP complex+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005732///small nucleolar ribonucleoprotein complex","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:1990226///histone methyltransferase binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis","IPR012976///NOSIC+++IPR029012///Helix hairpin bin domain superfamily+++IPR036070///Nop domain superfamily+++IPR002687///Nop domain+++IPR012974///NOP5, N-terminal","[NOP56_HUMAN|Reviewed]RecName: Full=Nucleolar protein 56; AltName: Full=Nucleolar protein 5A;+++[A0PJ92_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH18421.1}; Flags: Fragment;+++[H0Y653_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000403199}; Flags: Fragment;+++[H0YDU4_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000434317}; Flags: Fragment;+++[Q5JXT2_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 56 {ECO:0000313|Ensembl:ENSP00000388497}; Flags: Fragment;+++[Q9BSN3_HUMAN|Unreviewed]SubName: Full=NOP56 protein {ECO:0000313|EMBL:AAH04937.1};"]
[10529,"'NEBL'",5,16,10.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0031674///I band+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0030018///Z disc","GO:0005515///protein binding+++GO:0031005///filamin binding+++GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding+++GO:0008307///structural constituent of muscle+++GO:0005523///tropomyosin binding","GO:0071691///cardiac muscle thin filament assembly","IPR000900///Nebulin repeat+++IPR036028///SH3-like domain superfamily+++IPR001452///SH3 domain+++IPR001781///Zinc finger, LIM-type+++IPR035631///Nebulette, SH3 domain","[NEBL_HUMAN|Reviewed]RecName: Full=Nebulette; AltName: Full=Actin-binding Z-disk protein;+++[A0A0U1RQY0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489224}; Flags: Fragment;+++[A0A0U1RRI4_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489545}; Flags: Fragment;+++[A0A0U1RRK0_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000489562}; Flags: Fragment;+++[B0YJ47_HUMAN|Unreviewed]SubName: Full=Nebulette variant 4 {ECO:0000313|EMBL:ACA06025.1};+++[Q2TBD1_HUMAN|Unreviewed]SubName: Full=NEBL protein {ECO:0000313|EMBL:AAI10453.1};+++[Q59FZ8_HUMAN|Unreviewed]SubName: Full=Nebulette non-muscle isoform variant {ECO:0000313|EMBL:BAD92548.1}; Flags: Fragment;+++[Q5JUU7_HUMAN|Unreviewed]SubName: Full=Nebulette {ECO:0000313|Ensembl:ENSP00000396512}; Flags: Fragment;+++[Q5JUU8_HUMAN|Unreviewed]SubName: Full=Nebulette variant 6 {ECO:0000313|EMBL:ACA06021.1};"]
[10531,"'PITRM1'",2104,2112,2108,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0004222///metalloendopeptidase activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008047///enzyme activator activity+++GO:0046872///metal ion binding+++GO:0003824///catalytic activity","GO:0043085///positive regulation of catalytic activity+++GO:0006508///proteolysis+++GO:0006626///protein targeting to mitochondrion","IPR007863///Peptidase M16, C-terminal+++IPR013578///Peptidase M16C associated+++IPR011765///Peptidase M16, N-terminal+++IPR011249///Metalloenzyme, LuxS/M16 peptidase-like","[PREP_HUMAN|Reviewed]RecName: Full=Presequence protease, mitochondrial {ECO:0000305|PubMed:16849325}; Short=hPreP {ECO:0000303|PubMed:16849325}; EC=3.4.24.- {ECO:0000269|PubMed:10360838, ECO:0000269|PubMed:16849325, ECO:0000269|PubMed:19196155, ECO:0000269|PubMed:24931469}; AltName: Full=Pitrilysin metalloproteinase 1 {ECO:0000303|PubMed:10360838}; Short=Metalloprotease 1 {ECO:0000303|PubMed:10360838}; Short=hMP1 {ECO:0000303|PubMed:10360838}; Flags: Precursor;+++[A0A0A0MRX9_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000370382};+++[B1APQ0_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000399307}; Flags: Fragment;+++[B1APQ1_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000402072}; Flags: Fragment;+++[H0Y4F7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000391526}; Flags: Fragment;+++[H0Y7L7_HUMAN|Unreviewed]SubName: Full=Presequence protease, mitochondrial {ECO:0000313|Ensembl:ENSP00000413687}; Flags: Fragment;"]
[10533,"'ATG7'",242,219,230.5,"04136///Autophagy - other+++04140///Autophagy - animal+++04138///Autophagy - yeast+++04216///Ferroptosis",{"$nulls":3},"GO:0005930///axoneme+++GO:0034774///secretory granule lumen+++GO:0000407///phagophore assembly site+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0030424///axon+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity+++GO:0019778///Atg12 activating enzyme activity+++GO:0005515///protein binding+++GO:0008134///transcription factor binding+++GO:0019779///Atg8 activating enzyme activity+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0004839///ubiquitin activating enzyme activity","GO:0071315///cellular response to morphine+++GO:0006464///cellular protein modification process+++GO:0042752///regulation of circadian rhythm+++GO:0061025///membrane fusion+++GO:0006501///C-terminal protein lipidation+++GO:0016567///protein ubiquitination+++GO:0039521///suppression by virus of host autophagy+++GO:0000422///autophagy of mitochondrion+++GO:0051607///defense response to virus+++GO:0007568///aging+++GO:0031401///positive regulation of protein modification process+++GO:0045732///positive regulation of protein catabolic process+++GO:0060548///negative regulation of cell death+++GO:0043312///neutrophil degranulation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:1902617///response to fluoride+++GO:0090298///negative regulation of mitochondrial DNA replication+++GO:0006497///protein lipidation+++GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0006995///cellular response to nitrogen starvation+++GO:0043065///positive regulation of apoptotic process+++GO:0010508///positive regulation of autophagy+++GO:0031667///response to nutrient levels+++GO:1901214///regulation of neuron death+++GO:0016236///macroautophagy+++GO:0009749///response to glucose+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0044805///late nucleophagy+++GO:0071455///cellular response to hyperoxia+++GO:0000045///autophagosome assembly+++GO:0009267///cellular response to starvation+++GO:0061684///chaperone-mediated autophagy","IPR032197///Ubiquitin-like modifier-activating enzyme Atg7, N-terminal+++IPR035985///Ubiquitin-activating enzyme+++IPR006285///Ubiquitin-like modifier-activating enzyme Atg7+++IPR000594///THIF-type NAD/FAD binding fold","[ATG7_HUMAN|Reviewed]RecName: Full=Ubiquitin-like modifier-activating enzyme ATG7; AltName: Full=ATG12-activating enzyme E1 ATG7; AltName: Full=Autophagy-related protein 7; Short=APG7-like; Short=hAGP7; AltName: Full=Ubiquitin-activating enzyme E1-like protein;+++[A0A024R2E9_HUMAN|Unreviewed]SubName: Full=ATG7 autophagy related 7 homolog (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW64097.1};+++[B3KQM6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90740 fis, clone PLACE1011045, highly similar to Autophagy-related protein 7 {ECO:0000313|EMBL:BAG52088.1};+++[C9J415_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000411880}; Flags: Fragment;+++[C9JE55_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000416644}; Flags: Fragment;+++[C9JFF4_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000415223}; Flags: Fragment;+++[C9JGL2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000390547}; Flags: Fragment;+++[C9JKA3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389996}; Flags: Fragment;+++[C9JNU2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000408303}; Flags: Fragment;+++[F8WDY9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000389012};+++[H7BZ92_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000388295}; Flags: Fragment;+++[H7C059_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000393075}; Flags: Fragment;+++[H7C2J8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000406398}; Flags: Fragment;+++[H7C2R3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000407340}; Flags: Fragment;+++[H7C369_HUMAN|Unreviewed]SubName: Full=Ubiquitin-like modifier-activating enzyme ATG7 {ECO:0000313|Ensembl:ENSP00000409844}; Flags: Fragment;"]
[10534,"'SSSCA1'",480,376,428,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0030027///lamellipodium","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","IPR009563///Sjoegren syndrome/scleroderma autoantigen 1","[SSA27_HUMAN|Reviewed]RecName: Full=Sjoegren syndrome/scleroderma autoantigen 1; AltName: Full=Autoantigen p27;+++[E9PK41_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000431666};+++[E9PN57_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000432938};+++[G3V1B8_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000434381}; SubName: Full=Sjogren's syndrome/scleroderma autoantigen 1, isoform CRA_b {ECO:0000313|EMBL:EAW74407.1};+++[H0YEB6_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435432}; Flags: Fragment;+++[H0YEK1_HUMAN|Unreviewed]SubName: Full=Sjoegren syndrome/scleroderma autoantigen 1 {ECO:0000313|Ensembl:ENSP00000435982}; Flags: Fragment;"]
[10535,"'RNASEH2A'",74,69,71.5,"03030///DNA replication","H00290///Aicardi-Goutieres syndrome (AGS)",null,null,"GO:0032299///ribonuclease H2 complex+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin+++GO:0005667///transcription factor complex+++GO:0035976///transcription factor AP-1 complex+++GO:0000785///chromatin+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0004518///nuclease activity+++GO:0004540///ribonuclease activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003714///transcription corepressor activity+++GO:0004519///endonuclease activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042493///response to drug+++GO:0001649///osteoblast differentiation+++GO:0034097///response to cytokine+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006401///RNA catabolic process+++GO:0001570///vasculogenesis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0009987///cellular process+++GO:0010033///response to organic substance+++GO:0016070///RNA metabolic process+++GO:0001701///in utero embryonic development+++GO:0051591///response to cAMP+++GO:0009314///response to radiation+++GO:0043137///DNA replication, removal of RNA primer+++GO:0060136///embryonic process involved in female pregnancy+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032496///response to lipopolysaccharide+++GO:0046697///decidualization+++GO:0060716///labyrinthine layer blood vessel development+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0009612///response to mechanical stimulus+++GO:0006260///DNA replication+++GO:0071277///cellular response to calcium ion+++GO:0006298///mismatch repair+++GO:0001829///trophectodermal cell differentiation+++GO:0033687///osteoblast proliferation+++GO:0045597///positive regulation of cell differentiation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0051726///regulation of cell cycle+++GO:0032870///cellular response to hormone stimulus","IPR024567///Ribonuclease HII/HIII domain+++IPR023160///Ribonuclease HII, helix-loop-helix cap domain superfamily+++IPR000884///Thrombospondin type-1 (TSP1) repeat+++IPR012337///Ribonuclease H-like superfamily+++IPR036397///Ribonuclease H superfamily+++IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR004649///Ribonuclease H2, subunit A+++IPR001352///Ribonuclease HII/HIII","[RNH2A_HUMAN|Reviewed]RecName: Full=Ribonuclease H2 subunit A; Short=RNase H2 subunit A; EC=3.1.26.4; AltName: Full=Aicardi-Goutieres syndrome 4 protein; Short=AGS4; AltName: Full=RNase H(35); AltName: Full=Ribonuclease HI large subunit; Short=RNase HI large subunit; AltName: Full=Ribonuclease HI subunit A;+++[A0A2R8Y606_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[A0A2R8Y658_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515}; Flags: Fragment;+++[Q6IBG3_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};+++[Q6UQL6_HUMAN|Unreviewed]RecName: Full=Ribonuclease {ECO:0000256|RuleBase:RU003515}; EC=3.1.26.- {ECO:0000256|RuleBase:RU003515};"]
[10536,"'P3H3'",2001,1889,1945,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:1902494///catalytic complex","GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0051213///dioxygenase activity+++GO:0019797///procollagen-proline 3-dioxygenase activity+++GO:0046872///metal ion binding+++GO:0005506///iron ion binding+++GO:0016491///oxidoreductase activity+++GO:0031418///L-ascorbic acid binding","GO:0032964///collagen biosynthetic process+++GO:0032963///collagen metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0019511///peptidyl-proline hydroxylation+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0055114///oxidation-reduction process","IPR039839///Prolyl 3-hydroxylase 3+++IPR005123///Oxoglutarate/iron-dependent dioxygenase+++IPR039575///Prolyl 3-hydroxylase+++IPR006620///Prolyl 4-hydroxylase, alpha subunit","[P3H3_HUMAN|Reviewed]RecName: Full=Prolyl 3-hydroxylase 3 {ECO:0000312|HGNC:HGNC:19318}; EC=1.14.11.7; AltName: Full=Leprecan-like protein 2 {ECO:0000303|PubMed:15063763}; AltName: Full=Protein B {ECO:0000303|PubMed:8723724}; Flags: Precursor;"]
[105369140,"'LOC105369140'",2,7,4.5,"00380///Tryptophan metabolism+++01100///Metabolic pathways",null,"M00037///Melatonin biosynthesis, tryptophan => serotonin => melatonin","R04905///S-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-Methoxyindoleacetate+++R03130///S-Adenosyl-L-homocysteine:N-acetylserotonin O-methyltransferase S-Adenosyl-L-methionine + N-Acetylserotonin <=> S-Adenosyl-L-homocysteine + Melatonin",null,"GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR010630///Neuroblastoma breakpoint family (NBPF) domain+++IPR000477///Reverse transcriptase domain+++IPR013544///Domain of unknown function DUF1725+++IPR005135///Endonuclease/exonuclease/phosphatase","[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369155,"'105369155'",2,1,1.5,{"$nulls":7},"IPR006553///Leucine-rich repeat, cysteine-containing subtype+++IPR036047///F-box-like domain superfamily+++IPR001810///F-box domain+++IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily","[FBXL2_BOVIN|diamond]RecName: Full=F-box/LRR-repeat protein 2 {ECO:0000305}; AltName: Full=F-box and leucine-rich repeat protein 2 {ECO:0000305};"]
[105369199,"'LOC105369199'",5,2,3.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0030016///myofibril+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0032947///protein-containing complex scaffold activity+++GO:0019899///enzyme binding","GO:0034622///cellular protein-containing complex assembly+++GO:1903358///regulation of Golgi organization+++GO:0090063///positive regulation of microtubule nucleation+++GO:0030953///astral microtubule organization","IPR012943///Centrosomin, N-terminal motif 1+++IPR010630///Neuroblastoma breakpoint family (NBPF) domain","[CK5P2_HUMAN|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2; AltName: Full=CDK5 activator-binding protein C48; AltName: Full=Centrosome-associated protein 215;+++[CK5P2_PANTR|diamond]RecName: Full=CDK5 regulatory subunit-associated protein 2;+++[MYOME_HUMAN|diamond]RecName: Full=Myomegalin; AltName: Full=Cardiomyopathy-associated protein 2; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_MOUSE|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein;+++[MYOME_RAT|diamond]RecName: Full=Myomegalin; AltName: Full=Phosphodiesterase 4D-interacting protein; AltName: Full=Phosphodiesterase-binding protein clone 46;+++[NBP6L_BOVIN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6-like protein;+++[NBPF4_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 4;+++[NBPF5_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 5;+++[NBPF6_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 6;+++[NBPF7_HUMAN|diamond]RecName: Full=Putative neuroblastoma breakpoint family member 7;+++[NBPFC_HUMAN|diamond]RecName: Full=Neuroblastoma breakpoint family member 12; AltName: Full=Chromosome 1 amplified sequence 1;"]
[105369201,"'LOC105369201'",2,1,1.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0042803///protein homodimerization activity",null,"IPR031751///Protein of unknown function DUF4735","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369205,"'LOC105369205'",49,52,50.5,{"$nulls":4},"GO:0016021///integral component of membrane",{"$nulls":3},"[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369214,"'LOC105369214'",1,0,0.5,{"$nulls":8},"[Q9H5V2_HUMAN|Unreviewed]SubName: Full=cDNA: FLJ23003 fis, clone LNG00331 {ECO:0000313|EMBL:BAB15517.1};"]
[105369266,"'LOC105369266'",0,0.75,0.375,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity","GO:0006468///protein phosphorylation+++GO:0007265///Ras protein signal transduction+++GO:0042127///regulation of cell proliferation+++GO:0043410///positive regulation of MAPK cascade+++GO:0043405///regulation of MAP kinase activity+++GO:0019933///cAMP-mediated signaling+++GO:0000165///MAPK cascade","IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR025561///Kinase suppressor of RAS, SAM-like domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR011009///Protein kinase-like domain superfamily","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105369535,"'LOC105369535'",7,0,3.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":7},"[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105369591,"'LOC105369591'",1,0,0.5,{"$nulls":4},"GO:0005887///integral component of plasma membrane",null,"GO:0007224///smoothened signaling pathway+++GO:0060059///embryonic retina morphogenesis in camera-type eye+++GO:0007520///myoblast fusion+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0045663///positive regulation of myoblast differentiation+++GO:0048643///positive regulation of skeletal muscle tissue development+++GO:0021987///cerebral cortex development+++GO:0043497///regulation of protein heterodimerization activity+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0043410///positive regulation of MAPK cascade+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045666///positive regulation of neuron differentiation+++GO:0001708///cell fate specification+++GO:0002088///lens development in camera-type eye+++GO:0010172///embryonic body morphogenesis+++GO:0009952///anterior/posterior pattern specification","IPR013098///Immunoglobulin I-set+++IPR003599///Immunoglobulin subtype+++IPR003598///Immunoglobulin subtype 2+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003961///Fibronectin type III+++IPR013783///Immunoglobulin-like fold+++IPR032983///Cell adhesion molecule-related/down-regulated by oncogenes+++IPR036116///Fibronectin type III superfamily","[F7AQJ7_MACMU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMUP00000010025};"]
[105369728,"'LOC105369728'",1,0,0.5]
[105369869,"'LOC105369869'",0,1,0.5,{"$nulls":4},"GO:0005911///cell-cell junction+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0043005///neuron projection+++GO:0098793///presynapse+++GO:0070062///extracellular exosome+++GO:0045211///postsynaptic membrane+++GO:0045202///synapse+++GO:0097025///MPP7-DLG1-LIN7 complex+++GO:0005923///bicellular tight junction+++GO:0005622///intracellular","GO:0097016///L27 domain binding","GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0048489///synaptic vesicle transport+++GO:0048839///inner ear development+++GO:0007269///neurotransmitter secretion+++GO:1903361///protein localization to basolateral plasma membrane+++GO:0065003///protein-containing complex assembly+++GO:0006887///exocytosis+++GO:0015031///protein transport","IPR014775///L27 domain, C-terminal+++IPR004172///L27 domain+++IPR036034///PDZ superfamily+++IPR001478///PDZ domain+++IPR017365///Protein lin-7+++IPR036892///L27 domain superfamily","[LIN7A_BOVIN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A;+++[LIN7A_HUMAN|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=hLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Tax interaction protein 33; Short=TIP-33; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_MOUSE|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; Short=mLin-7; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;+++[LIN7A_RAT|diamond]RecName: Full=Protein lin-7 homolog A; Short=Lin-7A; AltName: Full=Mammalian lin-seven protein 1; Short=MALS-1; AltName: Full=Vertebrate lin-7 homolog 1; Short=Veli-1;"]
[10537,"'UBD'",3,0,1.5,{"$nulls":4},"GO:0016235///aggresome+++GO:0045211///postsynaptic membrane+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005576///extracellular region+++GO:0045202///synapse+++GO:0016021///integral component of membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0030054///cell junction+++GO:0098793///presynapse+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0038037///G protein-coupled receptor dimeric complex+++GO:0038039///G protein-coupled receptor heterodimeric complex+++GO:0042734///presynaptic membrane+++GO:0016020///membrane+++GO:0098982///GABA-ergic synapse+++GO:0005737///cytoplasm","GO:0099579///G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential+++GO:0005515///protein binding+++GO:0070628///proteasome binding+++GO:0004965///G protein-coupled GABA receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0006508///proteolysis+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0032446///protein modification by small protein conjugation+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0007194///negative regulation of adenylate cyclase activity+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016567///protein ubiquitination+++GO:0034341///response to interferon-gamma+++GO:0043687///post-translational protein modification+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070842///aggresome assembly+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0034612///response to tumor necrosis factor+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","IPR029071///Ubiquitin-like domain superfamily+++IPR000626///Ubiquitin domain+++IPR019956///Ubiquitin","[UBD_HUMAN|Reviewed]RecName: Full=Ubiquitin D; AltName: Full=Diubiquitin; AltName: Full=Ubiquitin-like protein FAT10;+++[A0A0G2JH67_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77196.1}; SubName: Full=Ubiquitin D {ECO:0000313|Ensembl:ENSP00000373137};+++[A0A0G2JKF9_HUMAN|Unreviewed]SubName: Full=GABBR1 {ECO:0000313|EMBL:AQY76823.1}; SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000416731};+++[A0A140T9S4_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000412044};+++[A0A140TA42_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000448763};+++[A0A1U9X8S6_HUMAN|Unreviewed]SubName: Full=UBD {ECO:0000313|EMBL:AQY77194.1};+++[C9J342_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417332}; Flags: Fragment;+++[C9JZG6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419755}; Flags: Fragment;+++[F8WAS6_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417663};+++[F8WAV2_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000417478};+++[F8WDC0_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000420602};+++[F8WF38_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid type B receptor subunit 1 {ECO:0000313|Ensembl:ENSP00000419356};"]
[105370045,"'105370045'",59,97,78,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0031005///filamin binding","GO:0061572///actin filament bundle organization+++GO:0061181///regulation of chondrocyte development","IPR028215///Refilin family","[RFLA_HUMAN|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A; Short=RefilinA;+++[RFLA_MOUSE|diamond]RecName: Full=Refilin-A; AltName: Full=Regulator of filamin protein A {ECO:0000303|PubMed:21709252}; Short=RefilinA;"]
[105370092,"'LOC105370092'",0,2,1,{"$nulls":8},"[TIGD1_HUMAN|diamond]RecName: Full=Tigger transposable element-derived protein 1;"]
[105370399,"'LOC105370399'",0,1,0.5,{"$nulls":4},"GO:0005654///nucleoplasm",null,null,"IPR016185///Pre-ATP-grasp domain superfamily+++IPR011764///Biotin carboxylation domain+++IPR005481///Biotin carboxylase-like, N-terminal domain","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370579,"'LOC105370579'",6,1,3.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":7},"[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370641,"'LOC105370641'",1,0,0.5,{"$nulls":8},"[A0A146R4I4_FUNHE|diamond]SubName: Full=HCG1778991 {ECO:0000313|EMBL:JAQ63352.1}; Flags: Fragment;+++[A0A287ANQ5_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000045530};+++[A0A287BB99_PIG|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSSCP00000053389};+++[A0A2G8KAB5_STIJA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PIK44956.1};+++[L8IFV1_9CETA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELR54012.1}; Flags: Fragment;"]
[105370687,"'LOC105370687'",19,15,17,"03013///RNA transport+++04214///Apoptosis - fly",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0008135///translation factor activity, RNA binding+++GO:0045296///cadherin binding+++GO:0003924///GTPase activity+++GO:0071074///eukaryotic initiation factor eIF2 binding+++GO:0003723///RNA binding+++GO:0005525///GTP binding+++GO:0003743///translation initiation factor activity","GO:0006446///regulation of translational initiation+++GO:0001731///formation of translation preinitiation complex+++GO:0006413///translational initiation+++GO:0090630///activation of GTPase activity","IPR016021///MIF4G-like domain superfamily+++IPR016024///Armadillo-type fold+++IPR002735///Translation initiation factor IF2/IF5+++IPR003307///W2 domain+++IPR016189///Translation initiation factor IF2/IF5, N-terminal+++IPR016190///Translation initiation factor IF2/IF5, zinc-binding","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[IF5_DROME|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_HUMAN|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_MOUSE|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_PONAB|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[IF5_RAT|diamond]RecName: Full=Eukaryotic translation initiation factor 5; Short=eIF-5;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105370691,"'LOC105370691'",1,0,0.5,{"$nulls":8},"[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;"]
[105370849,"'LOC105370849'",2,1,1.5,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0000137///Golgi cis cisterna+++GO:0005874///microtubule+++GO:0005801///cis-Golgi network+++GO:0000139///Golgi membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0000922///spindle pole+++GO:0072686///mitotic spindle+++GO:0032580///Golgi cisterna membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane","GO:0019905///syntaxin binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0019901///protein kinase binding+++GO:0045296///cadherin binding+++GO:0061676///importin-alpha family protein binding","GO:0090166///Golgi disassembly+++GO:0010507///negative regulation of autophagy+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0051289///protein homotetramerization+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048208///COPII vesicle coating+++GO:0060050///positive regulation of protein glycosylation+++GO:0006486///protein glycosylation+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0007020///microtubule nucleation+++GO:0090306///spindle assembly involved in meiosis+++GO:0032091///negative regulation of protein binding+++GO:0008356///asymmetric cell division+++GO:0090161///Golgi ribbon formation+++GO:0090307///mitotic spindle assembly","IPR024858///Golgin subfamily A","[GOG6D_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6D;+++[GOG8A_HUMAN|diamond]RecName: Full=Golgin subfamily A member 8A; AltName: Full=88 kDa Golgi matrix protein; Short=GM88; AltName: Full=GM88 autoantigen;+++[GOGA2_HUMAN|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8315394}; Short=GM130 {ECO:0000303|PubMed:26363069, ECO:0000303|PubMed:8315394}; AltName: Full=GM130 autoantigen {ECO:0000303|PubMed:8315394}; AltName: Full=Golgin-95 {ECO:0000303|PubMed:8315394};+++[GOGA2_MOUSE|diamond]RecName: Full=Golgin subfamily A member 2; AltName: Full=130 kDa cis-Golgi matrix protein; Short=GM130 {ECO:0000303|PubMed:21552007, ECO:0000303|PubMed:26165940};+++[GOGA2_RAT|diamond]RecName: Full=Golgin subfamily A member 2 {ECO:0000305}; AltName: Full=130 kDa cis-Golgi matrix protein {ECO:0000303|PubMed:8557739}; Short=GM130 {ECO:0000303|PubMed:8557739};+++[YO027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ45275, mitochondrial; Flags: Precursor;"]
[105371063,"'LOC105371063'",1,0,0.5,{"$nulls":8},"[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105371095,"'LOC105371095'",0,1,0.5,{"$nulls":8},"[PAWR_HUMAN|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_MOUSE|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4;+++[PAWR_RAT|diamond]RecName: Full=PRKC apoptosis WT1 regulator protein; AltName: Full=Prostate apoptosis response 4 protein; Short=Par-4; AltName: Full=Transcriptional repressor Par-4-like protein PAWR;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;"]
[105371191,"'LOC105371191'",0.7,0,0.35,{"$nulls":8},"[A0A1A9AN69_9APIC|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:SBT57668.1};"]
[105371215,"'LOC105371215'",0,2,1]
[105371242,"'PPIAL4H'",0,1,0.5,{"$nulls":4},"GO:0008021///synaptic vesicle+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0042470///melanosome+++GO:0005737///cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0031201///SNARE complex","GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0000149///SNARE binding+++GO:0005484///SNAP receptor activity+++GO:0019905///syntaxin binding","GO:0045732///positive regulation of protein catabolic process+++GO:0016192///vesicle-mediated transport+++GO:0006457///protein folding+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0015031///protein transport+++GO:0048280///vesicle fusion with Golgi apparatus","IPR024936///Cyclophilin-type peptidyl-prolyl cis-trans isomerase+++IPR029000///Cyclophilin-like domain superfamily+++IPR002130///Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain+++IPR020892///Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site","[A0A075B767_HUMAN|Unreviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase {ECO:0000256|RuleBase:RU363019}; Short=PPIase {ECO:0000256|RuleBase:RU363019}; EC=5.2.1.8 {ECO:0000256|RuleBase:RU363019};"]
[105371448,"'LOC105371448'",1,1,1,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070876///SOSS complex+++GO:0005887///integral component of plasma membrane",null,"GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0050885///neuromuscular process controlling balance+++GO:0007093///mitotic cell cycle checkpoint+++GO:0006281///DNA repair","IPR036179///Immunoglobulin-like domain superfamily+++IPR003599///Immunoglobulin subtype+++IPR003961///Fibronectin type III+++IPR019333///Integrator complex subunit 3+++IPR007110///Immunoglobulin-like domain+++IPR013783///Immunoglobulin-like fold+++IPR013098///Immunoglobulin I-set+++IPR036116///Fibronectin type III superfamily+++IPR003598///Immunoglobulin subtype 2","[IGDC3_HUMAN|diamond]RecName: Full=Immunoglobulin superfamily DCC subclass member 3; AltName: Full=Putative neuronal cell adhesion molecule; Flags: Precursor;+++[IGDC3_MOUSE|diamond]RecName: Full=Immunoglobulin superfamily DCC subclass member 3; AltName: Full=Putative neuronal cell adhesion molecule; Flags: Precursor;+++[INT3_DANRE|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[INT3_DROGR|diamond]RecName: Full=Integrator complex subunit 3 homolog; AltName: Full=SOSS complex subunit A homolog;+++[INT3_HUMAN|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[INT3_MOUSE|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[INT3_PONAB|diamond]RecName: Full=Integrator complex subunit 3; Short=Int3; AltName: Full=SOSS complex subunit A; AltName: Full=Sensor of single-strand DNA complex subunit A; Short=SOSS-A; Short=Sensor of ssDNA subunit A;+++[PRTGA_DANRE|diamond]RecName: Full=Protogenin A; Flags: Precursor;+++[PRTGB_DANRE|diamond]RecName: Full=Protogenin B; Flags: Precursor; Fragment;+++[PRTG_CHICK|diamond]RecName: Full=Protogenin; Flags: Precursor;"]
[105371763,"'LOC105371763'",20,6,13,"04550///Signaling pathways regulating pluripotency of stem cells",{"$nulls":3},"GO:0005634///nucleus","GO:0031491///nucleosome binding+++GO:0046872///metal ion binding+++GO:0042393///histone binding","GO:0035812///renal sodium excretion+++GO:2001161///negative regulation of histone H3-K79 methylation+++GO:0035811///negative regulation of urine volume+++GO:0010765///positive regulation of sodium ion transport+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0036359///renal potassium excretion","IPR034732///Extended PHD (ePHD) domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001965///Zinc finger, PHD-type+++IPR019787///Zinc finger, PHD-finger+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR011011///Zinc finger, FYVE/PHD-type","[AF10_HUMAN|diamond]RecName: Full=Protein AF-10 {ECO:0000305}; AltName: Full=ALL1-fused gene from chromosome 10 protein;+++[AF10_MOUSE|diamond]RecName: Full=Protein AF-10 {ECO:0000305};+++[AF17_HUMAN|diamond]RecName: Full=Protein AF-17; AltName: Full=ALL1-fused gene from chromosome 17 protein;+++[CISD3_HUMAN|diamond]RecName: Full=CDGSH iron-sulfur domain-containing protein 3, mitochondrial; AltName: Full=MitoNEET-related protein 2; Short=Miner2; AltName: Full=Mitochondrial inner NEET protein {ECO:0000303|PubMed:29259115}; Short=MiNT {ECO:0000303|PubMed:29259115}; Flags: Precursor;+++[YM2A_CAEEL|diamond]RecName: Full=Uncharacterized protein F54F2.2, isoform a;"]
[105371921,"'LOC105371921'",1,2,1.5]
[105371932,"'LOC105371932'",8,3,5.5,{"$nulls":4},"GO:0005634///nucleus","GO:0005524///ATP binding",null,"IPR029684///Schlafen family+++IPR038461///Schlafen, AAA domain superfamily+++IPR029671///Schlafen family member 5+++IPR007421///Schlafen, AAA domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[A0A2K5WEY0_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000035670};+++[A0A2K6C0W4_MACNE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000017314};"]
[105371944,"'LOC105371944'",0,2,1,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016328///lateral plasma membrane+++GO:0005874///microtubule+++GO:0005923///bicellular tight junction+++GO:0005912///adherens junction+++GO:0005813///centrosome","GO:0051087///chaperone binding+++GO:0048487///beta-tubulin binding+++GO:0005096///GTPase activator activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0031115///negative regulation of microtubule polymerization+++GO:0007023///post-chaperonin tubulin folding pathway+++GO:0034333///adherens junction assembly+++GO:0048667///cell morphogenesis involved in neuron differentiation+++GO:0070830///bicellular tight junction assembly+++GO:0006457///protein folding+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0000278///mitotic cell cycle+++GO:0007021///tubulin complex assembly","IPR011989///Armadillo-like helical+++IPR033162///Tubulin-folding cofactor D+++IPR016024///Armadillo-type fold+++IPR001173///Glycosyltransferase 2-like+++IPR022577///Tubulin-specific chaperone D, C-terminal+++IPR029044///Nucleotide-diphospho-sugar transferases","[Q6ZPB7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ26108 fis, clone SPL05107 {ECO:0000313|EMBL:BAC85197.1};"]
[105372204,"'LOC105372204'",1,0,0.5]
[105372269,"'LOC105372269'",10,5,7.5,{"$nulls":4},"GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004856///xylulokinase activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0004190///aspartic-type endopeptidase activity","GO:0042732///D-xylose metabolic process+++GO:0016032///viral process+++GO:0005997///xylulose metabolic process","IPR018484///Carbohydrate kinase, FGGY, N-terminal+++IPR036157///dUTPase-like superfamily+++IPR018485///Carbohydrate kinase, FGGY, C-terminal+++IPR000477///Reverse transcriptase domain+++IPR001969///Aspartic peptidase, active site+++IPR008919///Retrovirus capsid, N-terminal+++IPR003322///Beta-retroviral matrix protein+++IPR000467///G-patch domain+++IPR021109///Aspartic peptidase domain superfamily+++IPR034170///Retropepsin-like catalytic domain+++IPR033704///dUTPase, trimeric+++IPR000721///Retroviral nucleocapsid protein Gag+++IPR010999///Retroviral matrix protein+++IPR029054///dUTPase-like+++IPR001878///Zinc finger, CCHC-type+++IPR036875///Zinc finger, CCHC-type superfamily+++IPR038124///Beta-retroviral matrix superfamily+++IPR018061///Retropepsins+++IPR000577///Carbohydrate kinase, FGGY+++IPR008916///Retrovirus capsid, C-terminal+++IPR001995///Peptidase A2A, retrovirus, catalytic","[EN113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Env polyprotein; AltName: Full=EnvK5 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Env polyprotein; AltName: Full=EnvK3 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C19) envelope protein; AltName: Full=HERV-K_19q11 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K_11q22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Env polyprotein; AltName: Full=EnvK2 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K(C7) envelope protein; AltName: Full=HERV-K(HML-2.HOM) envelope protein; AltName: Full=HERV-K108 envelope protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ENK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Env polyprotein; AltName: Full=EnvK6 protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-K115 envelope protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[GAK21_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 21 Gag polyprotein; AltName: Full=HERV-K_12q14.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[VP113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pro protein; AltName: Full=HERV-K113 envelope protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[VPK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pro protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pro protein; EC=3.4.23.50; AltName: Full=Protease; AltName: Full=Proteinase; Short=PR;+++[XYLB_PONAB|diamond]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;"]
[105372315,"'LOC105372315'",0,5,2.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane",null,null,"IPR008981///F-MuLV receptor-binding+++IPR018154///TLV/ENV coat polyprotein","[ENVT1_HUMAN|Reviewed]RecName: Full=Endogenous retrovirus group S71 member 1 Env polyprotein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-T Env protein; AltName: Full=HERV-T_19q13.11 provirus ancestral Env polyprotein; Includes: RecName: Full=Surface protein; Short=SU; Includes: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;"]
[105372319,"'LOC105372319'",0,1,0.5,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type","[ZN626_HUMAN|diamond]RecName: Full=Zinc finger protein 626;+++[ZN695_HUMAN|diamond]RecName: Full=Zinc finger protein 695; AltName: Full=Zinc finger protein SBZF3;+++[ZN724_HUMAN|diamond]RecName: Full=Zinc finger protein 724 {ECO:0000305};+++[ZN737_HUMAN|diamond]RecName: Full=Zinc finger protein 737; AltName: Full=Zinc finger protein 102;+++[ZNF66_HUMAN|diamond]RecName: Full=Putative zinc finger protein 66; AltName: Full=Zinc finger protein 66 pseudogene;"]
[105372412,"'LOC105372412'",3,0,1.5,{"$nulls":7},"IPR016054///Ly-6 antigen/uPA receptor-like","[A0A091DT05_FUKDA|diamond]SubName: Full=Interferon-inducible GTPase 5 {ECO:0000313|EMBL:KFO33613.1};+++[A0A2Y9P5V2_DELLE|diamond]SubName: Full=uncharacterized protein LOC111180525 {ECO:0000313|RefSeq:XP_022440616.1};+++[L9L7Y3_TUPCH|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELW71071.1};+++[M3Y5G8_MUSPF|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMPUP00000006569};+++[Q8WYX9_HUMAN|diamond]SubName: Full=Uncharacterized protein pp10122 {ECO:0000313|EMBL:AAL55824.1};+++[S9YW18_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY88250.1};"]
[105372824,"'LOC105372824'",13,12,12.5,{"$nulls":8},"[A0A0B4J2C9_HUMAN|Unreviewed]SubName: Full=Pyridoxal kinase {ECO:0000313|Ensembl:ENSP00000479315};"]
[105372836,"'LOC105372836'",0,4,2]
[105372883,"'LOC105372883'",1,0,0.5]
[105372978,"'LINC01638'",11,15,13,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[105373091,"'LOC105373091'",1,1,1]
[105373102,"'LOC105373102'",11,25,18,"05166///HTLV-I infection+++04022///cGMP-PKG signaling pathway+++04020///Calcium signaling pathway+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04218///Cellular senescence+++04217///Necroptosis+++05016///Huntington's disease+++05012///Parkinson's disease","H01118///Progressive external ophthalmoplegia (PEO)+++H00469///Mitochondrial DNA depletion syndrome (MDS)",null,null,"GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005743///mitochondrial inner membrane","GO:0008171///O-methyltransferase activity+++GO:0015207///adenine transmembrane transporter activity+++GO:0051213///dioxygenase activity+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0005471///ATP:ADP antiporter activity+++GO:0046872///metal ion binding","GO:0006626///protein targeting to mitochondrion+++GO:0046902///regulation of mitochondrial membrane permeability+++GO:0050796///regulation of insulin secretion+++GO:0006915///apoptotic process+++GO:0010468///regulation of gene expression+++GO:0046732///active induction of host immune response by virus","IPR016461///O-methyltransferase COMT-type+++IPR001077///O-methyltransferase, family 2+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR019351///Protein of unknown function DUF2039+++IPR023395///Mitochondrial carrier domain superfamily+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR029516///Histone demethylase UTY+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase+++IPR002113///Adenine nucleotide translocator 1+++IPR003697///Maf-like protein+++IPR002067///Mitochondrial carrier protein+++IPR018108///Mitochondrial substrate/solute carrier+++IPR029001///Inosine triphosphate pyrophosphatase-like+++IPR031725///Acetylserotonin O-methyltransferase, dimerisation domain+++IPR019734///Tetratricopeptide repeat+++IPR013026///Tetratricopeptide repeat-containing domain","[ADT2_BOVIN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_HUMAN|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=ADP,ATP carrier protein, fibroblast isoform; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT2_PONAB|diamond]RecName: Full=ADP/ATP translocase 2; AltName: Full=ADP,ATP carrier protein 2; AltName: Full=Adenine nucleotide translocator 2; Short=ANT 2; AltName: Full=Solute carrier family 25 member 5; Contains: RecName: Full=ADP/ATP translocase 2, N-terminally processed;+++[ADT3_BOVIN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_HUMAN|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=ADP,ATP carrier protein, isoform T2; Short=ANT 2; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ADT3_PIG|diamond]RecName: Full=ADP/ATP translocase 3; AltName: Full=ADP,ATP carrier protein 3; AltName: Full=Adenine nucleotide translocator 3; Short=ANT 3; AltName: Full=Solute carrier family 25 member 6; Contains: RecName: Full=ADP/ATP translocase 3, N-terminally processed;+++[ASML_HUMAN|diamond]RecName: Full=N-acetylserotonin O-methyltransferase-like protein; Short=ASMTL; EC=2.1.1.-;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105373132,"'105373132'",3,4,3.5,{"$nulls":8},"[Q96N51_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31401 fis, clone NT2NE2000038 {ECO:0000313|EMBL:BAB71058.1};"]
[105373244,"'LOC105373244'",1,0,0.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0030027///lamellipodium","GO:0047394///glycerophosphoinositol inositolphosphodiesterase activity+++GO:0046872///metal ion binding+++GO:0008889///glycerophosphodiester phosphodiesterase activity","GO:0006629///lipid metabolic process+++GO:0090527///actin filament reorganization+++GO:0045669///positive regulation of osteoblast differentiation","IPR004129///Glycerophosphoryl diester phosphodiesterase+++IPR030395///Glycerophosphodiester phosphodiesterase domain+++IPR017946///PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily","[GDPD2_HUMAN|diamond]RecName: Full=Glycerophosphoinositol inositolphosphodiesterase GDPD2; EC=3.1.4.43; AltName: Full=Glycerophosphodiester phosphodiesterase 3; AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 2; AltName: Full=Osteoblast differentiation promoting factor;+++[GDPD2_MOUSE|diamond]RecName: Full=Glycerophosphoinositol inositolphosphodiesterase GDPD2; EC=3.1.4.43; AltName: Full=Glycerophosphodiester phosphodiesterase 3; AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 2; AltName: Full=Osteoblast differentiation promoting factor;+++[GDPD5_CHICK|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;+++[GDPD5_HUMAN|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;+++[GDPD5_MOUSE|diamond]RecName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 5; EC=3.1.-.-; AltName: Full=Glycerophosphodiester phosphodiesterase 2;"]
[105373289,"'LOC105373289'",3,0,1.5]
[105373311,"'LOC105373311'",108,98,103,{"$nulls":8},"[A0A1S3WQD2_ERIEU|diamond]SubName: Full=uncharacterized protein LOC107523152 {ECO:0000313|RefSeq:XP_016048578.1};+++[A0A2Y9FXY4_TRIMA|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC101348364 {ECO:0000313|RefSeq:XP_012411968.1};+++[A0A2Y9LSY7_DELLE|diamond]SubName: Full=LOW QUALITY PROTEIN: transcription factor Maf {ECO:0000313|RefSeq:XP_022412460.1};+++[B7Z208_HUMAN|diamond]SubName: Full=cDNA FLJ52622 {ECO:0000313|EMBL:BAH11694.1};"]
[105373759,"'LOC105373759'",4.23,9.01,6.62,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105373780,"'LOC105373780'",1,0,0.5]
[105373944,"'LOC105373944'",24,19,21.5,{"$nulls":8},"[A0A2U3ZY91_ODORO|diamond]SubName: Full=collagen alpha-1(I) chain-like {ECO:0000313|RefSeq:XP_012423953.1};"]
[105373989,"'LOC105373989'",4,10,7,"04060///Cytokine-cytokine receptor interaction+++04550///Signaling pathways regulating pluripotency of stem cells+++04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm+++GO:0071944///cell periphery","GO:0005125///cytokine activity+++GO:0046789///host cell surface receptor binding+++GO:0005179///hormone activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0042803///protein homodimerization activity+++GO:0008083///growth factor activity","GO:0046882///negative regulation of follicle-stimulating hormone secretion+++GO:0042981///regulation of apoptotic process+++GO:0009267///cellular response to starvation+++GO:0030154///cell differentiation+++GO:0006952///defense response+++GO:0046676///negative regulation of insulin secretion+++GO:0048178///negative regulation of hepatocyte growth factor biosynthetic process+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0032924///activin receptor signaling pathway+++GO:0001541///ovarian follicle development+++GO:0045444///fat cell differentiation+++GO:0009611///response to wounding+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0048468///cell development+++GO:0043408///regulation of MAPK cascade+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0060395///SMAD protein signal transduction+++GO:0060279///positive regulation of ovulation+++GO:0044320///cellular response to leptin stimulus+++GO:0032869///cellular response to insulin stimulus+++GO:0048599///oocyte development","IPR015615///Transforming growth factor-beta-related+++IPR029034///Cystine-knot cytokine+++IPR017948///Transforming growth factor beta, conserved site+++IPR000381///Inhibin, beta B subunit+++IPR001111///TGF-beta, propeptide+++IPR001839///Transforming growth factor-beta, C-terminal","[INHBB_BOVIN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_HUMAN|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_MOUSE|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_PIG|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;+++[INHBB_RAT|diamond]RecName: Full=Inhibin beta B chain; AltName: Full=Activin beta-B chain; Flags: Precursor;"]
[105374013,"'LOC105374013'",5,12,8.5,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0042788///polysomal ribosome","GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0044183///protein binding involved in protein folding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0042803///protein homodimerization activity+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0005198///structural molecule activity+++GO:0003676///nucleic acid binding","GO:0006915///apoptotic process+++GO:0002181///cytoplasmic translation+++GO:0010458///exit from mitosis+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:2000059///negative regulation of ubiquitin-dependent protein catabolic process+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0006310///DNA recombination+++GO:0016032///viral process+++GO:0021554///optic nerve development+++GO:0007093///mitotic cell cycle checkpoint+++GO:0015074///DNA integration+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0000027///ribosomal large subunit assembly+++GO:0006351///transcription, DNA-templated+++GO:0008616///queuosine biosynthetic process+++GO:0060041///retina development in camera-type eye","IPR000210///BTB/POZ domain+++IPR029104///Retro-transcribing virus envelope glycoprotein+++IPR036862///Integrase, C-terminal domain superfamily, retroviral+++IPR024253///Phosducin, thioredoxin-like domain+++IPR036397///Ribonuclease H superfamily+++IPR000328///Retroviral envelope protein GP41-like+++IPR031751///Protein of unknown function DUF4735+++IPR000721///Retroviral nucleocapsid protein Gag+++IPR038630///Ribosomal protein L24e/L24 superfamily+++IPR003308///Integrase, N-terminal zinc-binding domain+++IPR023442///Ribosomal protein L24e, conserved site+++IPR000477///Reverse transcriptase domain+++IPR036236///Zinc finger C2H2 superfamily+++IPR010661///Reverse transcriptase thumb+++IPR001584///Integrase, catalytic core+++IPR010999///Retroviral matrix protein+++IPR001037///Integrase, C-terminal, retroviral+++IPR011017///TRASH domain+++IPR036249///Thioredoxin-like superfamily+++IPR003322///Beta-retroviral matrix protein+++IPR002156///Ribonuclease H domain+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR017856///Integrase-like, N-terminal+++IPR036875///Zinc finger, CCHC-type superfamily+++IPR012337///Ribonuclease H-like superfamily+++IPR013087///Zinc finger C2H2-type+++IPR008916///Retrovirus capsid, C-terminal+++IPR038124///Beta-retroviral matrix superfamily+++IPR008919///Retrovirus capsid, N-terminal+++IPR001878///Zinc finger, CCHC-type+++IPR000988///Ribosomal protein L24e-related","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GA113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Gag polyprotein; AltName: Full=HERV-K113 Gag protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK24_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 24 Gag polyprotein; AltName: Full=HERV-K101 Gag protein; AltName: Full=HERV-K_22q11.21 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK5_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 5 Gag polyprotein; AltName: Full=HERV-K(II) Gag protein; AltName: Full=HERV-K_3q12.3 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GAK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Gag polyprotein; AltName: Full=HERV-K(C7) Gag protein; AltName: Full=HERV-K(HML-2.HOM) Gag protein; AltName: Full=HERV-K108 Gag protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Gag polyprotein; Short=Gag polyprotein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[PDCL3_BOVIN|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_HUMAN|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=HTPHLP; AltName: Full=PhPL3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_MOUSE|diamond]RecName: Full=Phosducin-like protein 3; AltName: Full=Viral IAP-associated factor 1; Short=VIAF-1;+++[PDCL3_PONAB|diamond]RecName: Full=Phosducin-like protein 3;+++[PDCL3_RAT|diamond]RecName: Full=Phosducin-like protein 3;+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK11_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 11 Pol protein; AltName: Full=HERV-K_3q27.2 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK7_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 7 Pol protein; AltName: Full=HERV-K(III) Pol protein; AltName: Full=HERV-K102 Pol protein; AltName: Full=HERV-K_1q22 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Pol protein; AltName: Full=HERV-K(C6) Gag-Pol protein; AltName: Full=HERV-K109 Gag-Pol protein; AltName: Full=HERV-K_6q14.1 provirus ancestral Gag-Pol polyprotein; Includes: RecName: Full=Protease; EC=3.4.23.50; AltName: Full=PR; AltName: Full=Retropepsin; Includes: RecName: Full=Reverse transcriptase/ribonuclease H; EC=2.7.7.49; EC=2.7.7.7; EC=3.1.26.4; AltName: Full=p66 RT;+++[RL24_BOVIN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_FELCA|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=Ribosomal protein L30;+++[RL24_HUMAN|diamond]RecName: Full=60S ribosomal protein L24; AltName: Full=60S ribosomal protein L30; AltName: Full=Large ribosomal subunit protein eL24 {ECO:0000303|PubMed:24524803};+++[RL24_MACFA|diamond]RecName: Full=60S ribosomal protein L24;+++[RL24_MOUSE|diamond]RecName: Full=60S ribosomal protein L24;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[ZBT11_HUMAN|diamond]RecName: Full=Zinc finger and BTB domain-containing protein 11;"]
[105374089,"'LOC105374089'",0,1,0.5,{"$nulls":4},"GO:0031514///motile cilium+++GO:0097545///axonemal outer doublet","GO:0070840///dynein complex binding","GO:2000574///regulation of microtubule motor activity+++GO:0003341///cilium movement+++GO:0036159///inner dynein arm assembly","IPR025252///Domain of unknown function DUF4200","[Q9NXP9_HUMAN|Unreviewed]SubName: Full=HCG1780190 {ECO:0000313|EMBL:EAW79365.1}; SubName: Full=cDNA FLJ20123 fis, clone COL06041 {ECO:0000313|EMBL:BAA90961.1};"]
[105374103,"'LOC105374103'",3.02,1,2.01,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity","GO:0015074///DNA integration","IPR031751///Protein of unknown function DUF4735","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[POK10_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 10 Pol protein; AltName: Full=HERV-K10 Pol protein; AltName: Full=HERV-K107 Pol protein; AltName: Full=HERV-K_5q33.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK18_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 18 Pol protein; AltName: Full=HERV-K(C1a) Pol protein; AltName: Full=HERV-K110 Pol protein; AltName: Full=HERV-K18 Pol protein; AltName: Full=HERV-K_1q23.3 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POL2_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 297; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[POL3_DROME|diamond]RecName: Full=Retrovirus-related Pol polyprotein from transposon 17.6; Includes: RecName: Full=Protease; EC=3.4.23.-; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105374301,"'LOC105374301'",54.54,51,52.77,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005813///centrosome+++GO:0030289///protein phosphatase 4 complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0019888///protein phosphatase regulator activity+++GO:0030674///protein binding, bridging","GO:0008380///RNA splicing+++GO:0006464///cellular protein modification process+++GO:0006397///mRNA processing+++GO:0010569///regulation of double-strand break repair via homologous recombination","IPR019351///Protein of unknown function DUF2039+++IPR015267///Protein phosphatase 4 core regulatory subunit R2","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[PP4R2_CHICK|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_HUMAN|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_MOUSE|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[PP4R2_PONAB|diamond]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 2;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105374378,"'LOC105374378'",1,3,2,"00030///Pentose phosphate pathway+++03010///Ribosome",null,"M00178///Ribosome, bacteria","R02750///2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP+++R01051///ATP:D-ribose 5-phosphotransferase ATP + D-Ribose <=> ADP + D-Ribose 5-phosphate","GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit","GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0003735///structural constituent of ribosome+++GO:0019200///carbohydrate kinase activity+++GO:0004747///ribokinase activity","GO:0019303///D-ribose catabolic process+++GO:0070125///mitochondrial translational elongation+++GO:0046835///carbohydrate phosphorylation+++GO:0070126///mitochondrial translational termination+++GO:0006098///pentose-phosphate shunt","IPR002139///Ribokinase/fructokinase+++IPR038584///Ribosomal protein L33 superfamily+++IPR011877///Ribokinase+++IPR011332///Zinc-binding ribosomal protein+++IPR002173///Carbohydrate/puine kinase, PfkB, conserved site+++IPR011611///Carbohydrate kinase PfkB+++IPR001705///Ribosomal protein L33+++IPR029056///Ribokinase-like","[RBSK_HUMAN|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000303|PubMed:17585908}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000269|PubMed:17585908};+++[RBSK_MOUSE|diamond]RecName: Full=Ribokinase {ECO:0000255|HAMAP-Rule:MF_03215, ECO:0000312|EMBL:AAH23339.1}; Short=RK {ECO:0000255|HAMAP-Rule:MF_03215}; EC=2.7.1.15 {ECO:0000255|HAMAP-Rule:MF_03215};+++[RM33_ANOGA|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_BOVIN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_HUMAN|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; AltName: Full=Mitochondrial large ribosomal subunit protein bL33m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[RM33_MOUSE|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;+++[RM33_TETNG|diamond]RecName: Full=39S ribosomal protein L33, mitochondrial; Short=L33mt; Short=MRP-L33; Flags: Precursor;"]
[105374811,"'LOC105374811'",11,2,6.5,"00230///Purine metabolism+++05166///HTLV-I infection+++00240///Pyrimidine metabolism+++03030///DNA replication+++03420///Nucleotide excision repair+++01100///Metabolic pathways+++03410///Base excision repair",null,"M00263///DNA polymerase epsilon complex","R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dTTP + DNA <=> Diphosphate + DNA+++R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dGTP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dCTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) dATP + DNA <=> Diphosphate + DNA","GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0036126///sperm flagellum+++GO:0030425///dendrite+++GO:0061827///sperm head+++GO:0008622///epsilon DNA polymerase complex+++GO:0005886///plasma membrane+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0097225///sperm midpiece+++GO:0005654///nucleoplasm+++GO:0009986///cell surface+++GO:0044297///cell body","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003677///DNA binding+++GO:0016496///substance P receptor activity+++GO:0046872///metal ion binding+++GO:0004995///tachykinin receptor activity+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046982///protein heterodimerization activity","GO:0002687///positive regulation of leukocyte migration+++GO:0070474///positive regulation of uterine smooth muscle contraction+++GO:0032230///positive regulation of synaptic transmission, GABAergic+++GO:0032224///positive regulation of synaptic transmission, cholinergic+++GO:0045777///positive regulation of blood pressure+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0042713///sperm ejaculation+++GO:0007268///chemical synaptic transmission+++GO:0010193///response to ozone+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0032197///transposition, RNA-mediated+++GO:0003051///angiotensin-mediated drinking behavior+++GO:0043117///positive regulation of vascular permeability+++GO:0045987///positive regulation of smooth muscle contraction+++GO:1902093///positive regulation of flagellated sperm motility+++GO:0007217///tachykinin receptor signaling pathway+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0045907///positive regulation of vasoconstriction+++GO:0050671///positive regulation of lymphocyte proliferation+++GO:0035094///response to nicotine+++GO:0035106///operant conditioning+++GO:0043966///histone H3 acetylation+++GO:0048266///behavioral response to pain+++GO:0045778///positive regulation of ossification+++GO:0009582///detection of abiotic stimulus+++GO:0032570///response to progesterone+++GO:0045471///response to ethanol+++GO:0002118///aggressive behavior+++GO:0046878///positive regulation of saliva secretion+++GO:0046887///positive regulation of hormone secretion+++GO:0060083///smooth muscle contraction involved in micturition+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006954///inflammatory response+++GO:0010996///response to auditory stimulus+++GO:0043278///response to morphine+++GO:0045760///positive regulation of action potential+++GO:0007616///long-term memory+++GO:0051496///positive regulation of stress fiber assembly+++GO:0010634///positive regulation of epithelial cell migration+++GO:0009408///response to heat+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0051602///response to electrical stimulus+++GO:0019233///sensory perception of pain+++GO:0008306///associative learning+++GO:0002526///acute inflammatory response+++GO:0006310///DNA recombination+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0035815///positive regulation of renal sodium excretion+++GO:0042755///eating behavior+++GO:0032355///response to estradiol+++GO:0014910///regulation of smooth muscle cell migration","IPR001681///Neurokinin receptor+++IPR003958///Transcription factor CBF/NF-Y/archaeal histone domain+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR013544///Domain of unknown function DUF1725+++IPR000477///Reverse transcriptase domain+++IPR017452///GPCR, rhodopsin-like, 7TM+++IPR000046///Neurokinin NK1 receptor+++IPR009072///Histone-fold+++IPR005135///Endonuclease/exonuclease/phosphatase+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily","[DPOE4_BOVIN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4;+++[DPOE4_HUMAN|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[DPOE4_MOUSE|diamond]RecName: Full=DNA polymerase epsilon subunit 4; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit 4; AltName: Full=DNA polymerase epsilon subunit p12;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NFYC_BOVIN|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NFYC_RAT|diamond]RecName: Full=Nuclear transcription factor Y subunit gamma; AltName: Full=CAAT box DNA-binding protein subunit C; AltName: Full=CCAAT-binding transcription factor subunit C; Short=CBF-C; AltName: Full=Nuclear transcription factor Y subunit C; Short=NF-YC;+++[NK1R_CANLF|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_CAVPO|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_HUMAN|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_MOUSE|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;+++[NK1R_RAT|diamond]RecName: Full=Substance-P receptor; Short=SPR; AltName: Full=NK-1 receptor; Short=NK-1R; AltName: Full=Tachykinin receptor 1;"]
[105375355,"'UPK3B'",129,77,103,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation+++04330///Notch signaling pathway","H01439///Williams-Beuren syndrome",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0010629///negative regulation of gene expression","IPR024831///Uroplakin-3+++IPR024828///Uroplakin-3b","[UPK3B_HUMAN|Reviewed]RecName: Full=Uroplakin-3b; Short=UP3b; AltName: Full=Uroplakin IIIb; Short=UPIIIb; AltName: Full=p35; Flags: Precursor;+++[A0A0J9YVS6_HUMAN|Unreviewed]SubName: Full=Uroplakin-3b {ECO:0000313|Ensembl:ENSP00000487650};"]
[105375938,"'LOC105375938'",1,0,0.5]
[105376204,"'LOC105376204'",8,11,9.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":7},"[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376335,"'LOC105376335'",0,1,0.5]
[105376341,"'LOC105376341'",0,1,0.5,{"$nulls":8},"[PK1L3_MOUSE|diamond]RecName: Full=Polycystic kidney disease protein 1-like 3; AltName: Full=PC1-like 3 protein; AltName: Full=Polycystin-1L3; Flags: Precursor;"]
[105376353,"'LOC105376353'",4,8,6,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0042803///protein homodimerization activity",null,"IPR031751///Protein of unknown function DUF4735","[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FTM_HUMAN|diamond]RecName: Full=Protein fantom; AltName: Full=Nephrocystin-8; AltName: Full=RPGR-interacting protein 1-like protein; Short=RPGRIP1-like protein;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;"]
[105376526,"'LOC105376526'",1,3,2,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0016021///integral component of membrane","GO:0003723///RNA binding","GO:0051028///mRNA transport","IPR018154///TLV/ENV coat polyprotein","[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[ENR1_HUMAN|diamond]RecName: Full=Endogenous retrovirus group 3 member 1 Env polyprotein; AltName: Full=ERV-3 envelope protein; Short=ERV3 envelope protein; AltName: Full=ERV3-1 envelope protein; AltName: Full=Envelope polyprotein; AltName: Full=HERV-R envelope protein; Short=ERV-R envelope protein; AltName: Full=HERV-R_7q21.2 provirus ancestral Env polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ERK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Rec protein; AltName: Full=Endogenous retrovirus group K member 25; AltName: Full=HERV-K_11q22.1 provirus Rec protein;+++[POL1_MOUSE|diamond]RecName: Full=Retrovirus-related Pol polyprotein; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; Flags: Fragment;+++[REC19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Rec protein; AltName: Full=HERV-K(C19) Rec protein; AltName: Full=HERV-K_19q11 provirus Rec protein;+++[REC6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Rec protein; AltName: Full=Central open reading frame; Short=c-orf; Short=cORF; AltName: Full=Endogenous retrovirus K protein 6; AltName: Full=HERV-K(C7) Rec protein; AltName: Full=HERV-K(HML-2.HOM) Rec protein; AltName: Full=HERV-K108 Rec protein; AltName: Full=HERV-K_7p22.1 provirus Rec protein; AltName: Full=K-Rev; AltName: Full=Rev-like protein; AltName: Full=Rev/Rex homolog;+++[REC9_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 9 Rec protein; AltName: Full=HERV-K(C6) Rec protein; AltName: Full=HERV-K109 Rec protein; AltName: Full=HERV-K_6q14.1 provirus Rec protein;+++[RECK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Rec protein; AltName: Full=HERV-K115 Rec protein; AltName: Full=HERV-K_8p23.1 provirus Rec protein;+++[SYCY2_CALJA|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PANTR|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[SYCY2_PONPY|diamond]RecName: Full=Syncytin-2; AltName: Full=ERV-FRD provirus ancestral Env polyprotein; AltName: Full=Envelope polyprotein; Contains: RecName: Full=Surface protein; Short=SU; Contains: RecName: Full=Transmembrane protein; Short=TM; Flags: Precursor;+++[ZMAT1_HUMAN|diamond]RecName: Full=Zinc finger matrin-type protein 1;+++[ZN283_HUMAN|diamond]RecName: Full=Zinc finger protein 283; AltName: Full=Zinc finger protein HZF19;"]
[105376678,"'LOC105376678'",0,1,0.5,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0005813///centrosome+++GO:0031616///spindle pole centrosome+++GO:0005615///extracellular space+++GO:0032993///protein-DNA complex+++GO:0009986///cell surface+++GO:0005654///nucleoplasm+++GO:0005925///focal adhesion+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005730///nucleolus","GO:0042393///histone binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0033613///activating transcription factor binding+++GO:0051082///unfolded protein binding+++GO:0043024///ribosomal small subunit binding+++GO:0051059///NF-kappaB binding+++GO:0019901///protein kinase binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0030246///carbohydrate binding+++GO:0003713///transcription coactivator activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0008134///transcription factor binding+++GO:0043023///ribosomal large subunit binding+++GO:0030957///Tat protein binding+++GO:0001047///core promoter binding+++GO:0004860///protein kinase inhibitor activity+++GO:0003723///RNA binding","GO:0042255///ribosome assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060699///regulation of endoribonuclease activity+++GO:0007569///cell aging+++GO:0045727///positive regulation of translation+++GO:0046599///regulation of centriole replication+++GO:1902629///regulation of mRNA stability involved in cellular response to UV+++GO:0007098///centrosome cycle+++GO:0008104///protein localization+++GO:0051259///protein complex oligomerization+++GO:0034644///cellular response to UV+++GO:0010826///negative regulation of centrosome duplication+++GO:0006886///intracellular protein transport+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006913///nucleocytoplasmic transport+++GO:0032071///regulation of endodeoxyribonuclease activity+++GO:0016032///viral process+++GO:0008284///positive regulation of cell proliferation+++GO:0007166///cell surface receptor signaling pathway+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0060735///regulation of eIF2 alpha phosphorylation by dsRNA+++GO:0006281///DNA repair+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043066///negative regulation of apoptotic process+++GO:0050776///regulation of immune response+++GO:0008285///negative regulation of cell proliferation+++GO:0006334///nucleosome assembly+++GO:0044387///negative regulation of protein kinase activity by regulation of protein phosphorylation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0007165///signal transduction","IPR032569///Nucleophosmin, C-terminal+++IPR016187///C-type lectin fold+++IPR024057///Nucleoplasmin core domain+++IPR001304///C-type lectin-like+++IPR033992///Natural killer cell receptor-like, C-type lectin-like domain+++IPR036595///Alpha-macroglobulin, receptor-binding domain superfamily+++IPR001599///Alpha-2-macroglobulin+++IPR008930///Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid+++IPR036824///Nucleoplasmin core domain superfamily+++IPR019565///Alpha-2-macroglobulin, thiol-ester bond-forming+++IPR004301///Nucleoplasmin family+++IPR011625///Alpha-2-macroglobulin, N-terminal 2+++IPR016186///C-type lectin-like/link domain superfamily+++IPR014756///Immunoglobulin E-set+++IPR009048///Alpha-macroglobulin, receptor-binding+++IPR002890///Alpha-2-macroglobulin, N-terminal+++IPR011626///Alpha-macroglobulin complement component+++IPR013783///Immunoglobulin-like fold+++IPR038101///Nucleophosmin, C-terminal domain superfamily","[A2MG_MOUSE|diamond]RecName: Full=Alpha-2-macroglobulin-P; AltName: Full=Alpha-2-macroglobulin; Flags: Precursor;+++[A2MG_RAT|diamond]RecName: Full=Alpha-2-macroglobulin; Short=Alpha-2-M; Flags: Precursor;+++[CL2DB_RAT|diamond]RecName: Full=C-type lectin domain family 2 member D11; AltName: Full=C-type lectin-related protein B; Short=Clr-b; AltName: Full=Lectin-like transmembrane protein; AltName: Full=Osteoclast inhibitory lectin;+++[CLC2D_HUMAN|diamond]RecName: Full=C-type lectin domain family 2 member D; AltName: Full=Lectin-like NK cell receptor; AltName: Full=Lectin-like transcript 1; Short=LLT-1; AltName: Full=Osteoclast inhibitory lectin;+++[CLC2D_MOUSE|diamond]RecName: Full=C-type lectin domain family 2 member D; AltName: Full=C-type lectin-related protein B; Short=Clr-b; AltName: Full=Lectin-like transmembrane protein; AltName: Full=Osteoclast inhibitory lectin;+++[CLC2G_MOUSE|diamond]RecName: Full=C-type lectin domain family 2 member G; AltName: Full=DDV10; AltName: Full=Osteoclast inhibitory lectin-related protein 1; Short=Ocil-related protein 1;+++[CLC2H_MOUSE|diamond]RecName: Full=C-type lectin domain family 2 member H; AltName: Full=C-type lectin-related protein F; Short=Clr-f;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NPM_BOVIN|diamond]RecName: Full=Nucleophosmin; Short=NPM;+++[NPM_CHICK|diamond]RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;+++[NPM_HUMAN|diamond]RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;+++[NPM_MOUSE|diamond]RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;+++[NPM_RAT|diamond]RecName: Full=Nucleophosmin; Short=NPM; AltName: Full=Nucleolar phosphoprotein B23; AltName: Full=Nucleolar protein NO38; AltName: Full=Numatrin;+++[OVOS1_HUMAN|diamond]RecName: Full=Ovostatin homolog 1; Flags: Precursor;+++[OVOS2_HUMAN|diamond]RecName: Full=Ovostatin homolog 2; Flags: Precursor;+++[OVOS_CHICK|diamond]RecName: Full=Ovostatin; AltName: Full=Ovomacroglobulin; Flags: Precursor;+++[OVOS_MOUSE|diamond]RecName: Full=Ovostatin homolog; Flags: Precursor;"]
[105376684,"'LOC105376684'",4.59,2.34,3.465,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":7},"[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105376722,"'LOC105376722'",1,0,0.5,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"IPR026737///Golgin subfamily A member 6-like+++IPR024858///Golgin subfamily A","[GG6L3_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 6-like protein 3;+++[GG6L4_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 4;+++[GG6L9_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 9 {ECO:0000305};+++[GG6LA_HUMAN|diamond]RecName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000305};+++[GG6LS_HUMAN|diamond]RecName: Full=Putative golgin subfamily A member 6-like protein 19;+++[U2Q2L_HUMAN|diamond]RecName: Full=Putative ubiquitin-conjugating enzyme E2Q2-like protein;"]
[105376906,"'LOC105376906'",26,18,22,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity","GO:0006310///DNA recombination+++GO:0015074///DNA integration","IPR036397///Ribonuclease H superfamily+++IPR000477///Reverse transcriptase domain+++IPR003308///Integrase, N-terminal zinc-binding domain+++IPR002156///Ribonuclease H domain+++IPR017856///Integrase-like, N-terminal+++IPR001037///Integrase, C-terminal, retroviral+++IPR010661///Reverse transcriptase thumb+++IPR012337///Ribonuclease H-like superfamily+++IPR001584///Integrase, catalytic core+++IPR036862///Integrase, C-terminal domain superfamily, retroviral","[PO113_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 113 Pol protein; AltName: Full=HERV-K113 Pol protein; AltName: Full=HERV-K_19p13.11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK19_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 19 Pol protein; AltName: Full=HERV-K(C19) Pol protein; AltName: Full=HERV-K_19q11 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK25_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 25 Pol protein; AltName: Full=HERV-K_11q22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK6_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 6 Pol protein; AltName: Full=HERV-K(C7) Pol protein; AltName: Full=HERV-K(HML-2.HOM) Pol protein; AltName: Full=HERV-K108 Pol protein; AltName: Full=HERV-K_7p22.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;+++[POK8_HUMAN|diamond]RecName: Full=Endogenous retrovirus group K member 8 Pol protein; AltName: Full=HERV-K115 Pol protein; AltName: Full=HERV-K_8p23.1 provirus ancestral Pol protein; Includes: RecName: Full=Reverse transcriptase; Short=RT; EC=2.7.7.49; Includes: RecName: Full=Ribonuclease H; Short=RNase H; EC=3.1.26.4; Includes: RecName: Full=Integrase; Short=IN;"]
[105377022,"'LOC105377022'",8,1,4.5]
[105377622,"'LOC105377622'",1,0,0.5,{"$nulls":8},"[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105377650,"'LOC105377650'",12,26,19,{"$nulls":8},"[A0A1B0GRK0_MOUSE|diamond]SubName: Full=Predicted gene 45521 {ECO:0000313|Ensembl:ENSMUSP00000147554};+++[A0A2I2UDG9_FELCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSFCAP00000030524};+++[G3HFM3_CRIGR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGV92989.1};+++[L5K8U9_PTEAL|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ELK07797.1};+++[S9WRC2_CAMFR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EPY81017.1};"]
[105377777,"'LOC105377777'",3,2,2.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"IPR019351///Protein of unknown function DUF2039","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105377805,"'LOC105377805'",5,1,3,{"$nulls":8},"[A0A026VVN5_OOCBI|diamond]SubName: Full=F-box only protein {ECO:0000313|EMBL:EZA47853.1};+++[A0A060YYP9_ONCMY|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CDQ96866.1}; Flags: Fragment;+++[A0A093I0R1_STRCA|diamond]SubName: Full=Putative proline-rich protein 21 {ECO:0000313|EMBL:KFV87521.1}; Flags: Fragment;+++[A0A099ZME2_TINGU|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KGL82088.1}; Flags: Fragment;+++[A0A2T7NET3_POMCA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:PVD19655.1};"]
[105378592,"'105378592'",1,1,1]
[105378803,"'LRRC53'",1,0,0.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IPR001611///Leucine-rich repeat+++IPR003591///Leucine-rich repeat, typical subtype+++IPR032675///Leucine-rich repeat domain superfamily","[LRC53_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 53;"]
[105378862,"'LOC105378862'",70,57,63.5,{"$nulls":8},"[F6VET6_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000009862};+++[F7DFZ3_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000012093};+++[F7DXK1_HORSE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSECAP00000017383};"]
[105378949,"'LOC105378949'",16,12,14]
[105379045,"'105379045'",2,1,1.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":7},"[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379177,"'LOC105379177'",2.8,7.89,5.345,{"$nulls":4},"GO:0016021///integral component of membrane",{"$nulls":3},"[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379282,"'LOC105379282'",2,0,1,{"$nulls":8},"[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;"]
[105379356,"'LOC105379356'",0,1,0.5,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0003676///nucleic acid binding+++GO:0004523///RNA-DNA hybrid ribonuclease activity",null,"IPR012337///Ribonuclease H-like superfamily+++IPR036397///Ribonuclease H superfamily+++IPR002156///Ribonuclease H domain","[A0A087X0J2_HUMAN|diamond]SubName: Full=UBX domain-containing protein 8 {ECO:0000313|Ensembl:ENSP00000483433}; Flags: Fragment;+++[A0A2U3ZSI3_ODORO|diamond]SubName: Full=LOW QUALITY PROTEIN: uncharacterized protein LOC105758093 {ECO:0000313|RefSeq:XP_012421949.1};+++[Q1KYL9_MOUSE|diamond]SubName: Full=Gag-pro-pol polyprotein {ECO:0000313|EMBL:ABD14436.1}; Flags: Precursor;+++[Q1KYM2_MOUSE|diamond]SubName: Full=Gag-pro-pol polyprotein {ECO:0000313|EMBL:ABD14433.1}; Flags: Precursor;+++[Q86UH8_HUMAN|diamond]SubName: Full=Pol protein {ECO:0000313|EMBL:AAP29639.1};"]
[105379443,"'LOC105379443'",26.37,36.92,31.645,"04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal+++00670///One carbon pool by folate",null,"M00141///C1-unit interconversion, eukaryotes","R00943///Formate:tetrahydrofolate ligase (ADP-forming) Tetrahydrofolate + Formate + ATP <=> ADP + Orthophosphate + 10-Formyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0016805///dipeptidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004488///methylenetetrahydrofolate dehydrogenase (NADP+) activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0008239///dipeptidyl-peptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005524///ATP binding+++GO:0004477///methenyltetrahydrofolate cyclohydrolase activity+++GO:0008236///serine-type peptidase activity+++GO:0043565///sequence-specific DNA binding+++GO:0050129///N-formylglutamate deformylase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0042803///protein homodimerization activity+++GO:0004329///formate-tetrahydrofolate ligase activity","GO:0015942///formate metabolic process+++GO:0042135///neurotransmitter catabolic process+++GO:0046655///folic acid metabolic process+++GO:0009113///purine nucleobase biosynthetic process+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0008652///cellular amino acid biosynthetic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0035999///tetrahydrofolate interconversion+++GO:0006760///folic acid-containing compound metabolic process+++GO:0001843///neural tube closure+++GO:0006351///transcription, DNA-templated+++GO:0009257///10-formyltetrahydrofolate biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0030154///cell differentiation+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0006310///DNA recombination+++GO:0006508///proteolysis+++GO:0048703///embryonic viscerocranium morphogenesis","IPR000672///Tetrahydrofolate dehydrogenase/cyclohydrolase+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR018379///BEN domain+++IPR036291///NAD(P)-binding domain superfamily+++IPR013544///Domain of unknown function DUF1725+++IPR030456///Fork head domain conserved site 2+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR018122///Fork head domain conserved site1+++IPR001766///Fork head domain+++IPR000477///Reverse transcriptase domain+++IPR005135///Endonuclease/exonuclease/phosphatase+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR036757///Transferrin receptor-like, dimerisation domain superfamily+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003137///PA domain+++IPR007365///Transferrin receptor-like, dimerisation domain+++IPR020628///Formate-tetrahydrofolate ligase, FTHFS, conserved site+++IPR020630///Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain+++IPR020631///Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain+++IPR039373///Glutamate carboxypeptidase 2-like+++IPR007484///Peptidase M28+++IPR000559///Formate-tetrahydrofolate ligase, FTHFS","[BEND2_HUMAN|diamond]RecName: Full=BEN domain-containing protein 2;+++[C1TC_HUMAN|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3; Contains: RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed;+++[C1TC_PONAB|diamond]RecName: Full=C-1-tetrahydrofolate synthase, cytoplasmic; Short=C1-THF synthase; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; EC=1.5.1.5; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase; EC=3.5.4.9; Includes: RecName: Full=Formyltetrahydrofolate synthetase; EC=6.3.4.3;+++[C1TM_BOVIN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_HUMAN|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[C1TM_MOUSE|diamond]RecName: Full=Monofunctional C1-tetrahydrofolate synthase, mitochondrial; EC=6.3.4.3; AltName: Full=Formyltetrahydrofolate synthetase; Flags: Precursor;+++[CH049_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf49;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[FOLH1_HUMAN|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Cell growth-inhibiting gene 27 protein; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen; Short=PSM; Short=PSMA; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_MOUSE|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOLH1_PIG|diamond]RecName: Full=Glutamate carboxypeptidase 2; EC=3.4.17.21; AltName: Full=Folate hydrolase 1; AltName: Full=Folylpoly-gamma-glutamate carboxypeptidase; Short=FGCP; AltName: Full=Glutamate carboxypeptidase II; Short=GCPII; AltName: Full=Membrane glutamate carboxypeptidase; Short=mGCP; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase I; Short=NAALADase I; AltName: Full=Prostate-specific membrane antigen homolog; AltName: Full=Pteroylpoly-gamma-glutamate carboxypeptidase;+++[FOXD4_HUMAN|diamond]RecName: Full=Forkhead box protein D4; AltName: Full=Forkhead-related protein FKHL9; AltName: Full=Forkhead-related transcription factor 5; Short=FREAC-5; AltName: Full=Myeloid factor-alpha;+++[FX4L3_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 3; Short=FOXD4-like 3;+++[FX4L4_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 4 {ECO:0000305}; Short=FOXD4-like 4 {ECO:0000305}; AltName: Full=Forkhead box protein D4-like 2 {ECO:0000312|HGNC:HGNC:23762}; AltName: Full=Forkhead box protein D4B {ECO:0000305|PubMed:12234674}; AltName: Full=Myeloid factor-gamma {ECO:0000312|EMBL:AAL73342.1};+++[FX4L5_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 5; Short=FOXD4-like 5;+++[FX4L6_HUMAN|diamond]RecName: Full=Forkhead box protein D4-like 6; Short=FOXD4-like 6;+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[NALD2_HUMAN|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[NALD2_MOUSE|diamond]RecName: Full=N-acetylated-alpha-linked acidic dipeptidase 2; EC=3.4.17.21; AltName: Full=Glutamate carboxypeptidase III; Short=GCPIII; AltName: Full=N-acetylaspartylglutamate peptidase II; Short=NAAG-peptidase II; AltName: Full=N-acetylated-alpha-linked acidic dipeptidase II; Short=NAALADase II;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[105379473,"'LOC105379473'",0,0.75,0.375,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0051087///chaperone binding+++GO:0071889///14-3-3 protein binding+++GO:0008022///protein C-terminus binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0051879///Hsp90 protein binding+++GO:0005524///ATP binding","GO:0042127///regulation of cell proliferation+++GO:0000165///MAPK cascade+++GO:0019933///cAMP-mediated signaling+++GO:0006468///protein phosphorylation+++GO:0043410///positive regulation of MAPK cascade+++GO:0007265///Ras protein signal transduction+++GO:0043405///regulation of MAP kinase activity","IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR025561///Kinase suppressor of RAS, SAM-like domain","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105379474,"'LOC105379474'",0,0.75,0.375,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0031434///mitogen-activated protein kinase kinase binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0005524///ATP binding+++GO:0071889///14-3-3 protein binding+++GO:0008022///protein C-terminus binding+++GO:0051879///Hsp90 protein binding+++GO:0046872///metal ion binding+++GO:0051087///chaperone binding+++GO:0004672///protein kinase activity","GO:0007265///Ras protein signal transduction+++GO:0006468///protein phosphorylation+++GO:0019933///cAMP-mediated signaling+++GO:0000165///MAPK cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation","IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR025561///Kinase suppressor of RAS, SAM-like domain+++IPR000719///Protein kinase domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105379545,"'LOC105379545'",0,0.75,0.375,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0032587///ruffle membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0071889///14-3-3 protein binding+++GO:0008022///protein C-terminus binding+++GO:0005524///ATP binding+++GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0005078///MAP-kinase scaffold activity+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0031434///mitogen-activated protein kinase kinase binding","GO:0000165///MAPK cascade+++GO:0006468///protein phosphorylation+++GO:0043405///regulation of MAP kinase activity+++GO:0042127///regulation of cell proliferation+++GO:0019933///cAMP-mediated signaling+++GO:0043410///positive regulation of MAPK cascade+++GO:0007265///Ras protein signal transduction","IPR025561///Kinase suppressor of RAS, SAM-like domain+++IPR000719///Protein kinase domain+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily","[KSR1_HUMAN|diamond]RecName: Full=Kinase suppressor of Ras 1;+++[KSR1_MOUSE|diamond]RecName: Full=Kinase suppressor of Ras 1; Short=mKSR1; AltName: Full=Protein Hb;"]
[105379547,"'LOC105379547'",2.3,7,4.65,{"$nulls":8},"[A0A2I2YCC5_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000032450};+++[A0A2I2YHS6_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000034480};+++[A0A2I2Z815_GORGO|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSGGOP00000043246};+++[A0A2I3ST96_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000080167};+++[A0A2I3TT44_PANTR|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000092156};"]
[105379554,"'LOC105379554'",90.17,92.31,91.24,{"$nulls":4},"GO:0005730///nucleolus+++GO:0036126///sperm flagellum+++GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0060271///cilium assembly+++GO:0060294///cilium movement involved in cell motility+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0030317///flagellated sperm motility","IPR000435///Tektin","[MAFIP_HUMAN|diamond]RecName: Full=MaFF-interacting protein; AltName: Full=Tektin-4 like protein PP5644;+++[TEKT4_BOVIN|diamond]RecName: Full=Tektin-4;+++[TEKT4_HUMAN|diamond]RecName: Full=Tektin-4;+++[TEKT4_MOUSE|diamond]RecName: Full=Tektin-4; AltName: Full=Testicular microtubules-related protein 4;+++[TEKT4_RAT|diamond]RecName: Full=Tektin-4;"]
[105379561,"'LOC105379561'",15,5,10,{"$nulls":8},"[A0A0D9SCH2_CHLSB|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSCSAP00000018561};+++[A0A1A9ADJ3_9APIC|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:SBT54262.1};"]
[105379575,"'105379575'",12,7,9.5,{"$nulls":8},"[CO3A1_RAT|diamond]RecName: Full=Collagen alpha-1(III) chain; Flags: Precursor;+++[CO4A2_ASCSU|diamond]RecName: Full=Collagen alpha-2(IV) chain; Flags: Precursor;+++[CO4A2_CAEEL|diamond]RecName: Full=Collagen alpha-2(IV) chain; AltName: Full=Lethal protein 2; Flags: Precursor;+++[LWA_ANTEL|diamond]RecName: Full=LWamide neuropeptides; Contains: RecName: Full=LWamide I; Contains: RecName: Full=Metamorphosin A; Short=MMA; AltName: Full=LWamide II; Contains: RecName: Full=LWamide III; Contains: RecName: Full=LWamide IV; Contains: RecName: Full=LWamide V; Contains: RecName: Full=LWamide VI; Contains: RecName: Full=LWamide VII; Contains: RecName: Full=LWamide VIII; Contains: RecName: Full=LWamide IX; Flags: Precursor;+++[MUC2_HUMAN|diamond]RecName: Full=Mucin-2; Short=MUC-2; AltName: Full=Intestinal mucin-2; Flags: Precursor;"]
[105379752,"'LOC105379752'",0,1,0.5,{"$nulls":8},"[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;"]
[10539,"'GLRX3'",791,623,707,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005938///cell cortex+++GO:0030018///Z disc","GO:0009055///electron transfer activity+++GO:0003723///RNA binding+++GO:0015038///glutathione disulfide oxidoreductase activity+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0051536///iron-sulfur cluster binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding","GO:0002026///regulation of the force of heart contraction+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process+++GO:0097428///protein maturation by iron-sulfur cluster transfer+++GO:0044571///[2Fe-2S] cluster assembly+++GO:0010614///negative regulation of cardiac muscle hypertrophy+++GO:0006879///cellular iron ion homeostasis+++GO:0022900///electron transport chain","IPR002109///Glutaredoxin+++IPR004480///Monothiol glutaredoxin-related+++IPR036249///Thioredoxin-like superfamily+++IPR033658///Glutaredoxin, PICOT-like+++IPR013766///Thioredoxin domain","[GLRX3_HUMAN|Reviewed]RecName: Full=Glutaredoxin-3; AltName: Full=PKC-interacting cousin of thioredoxin {ECO:0000303|PubMed:10636891}; Short=PICOT {ECO:0000303|PubMed:10636891}; AltName: Full=PKC-theta-interacting protein; Short=PKCq-interacting protein; AltName: Full=Thioredoxin-like protein 2;+++[A0A140VJK1_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 75 {ECO:0000313|EMBL:AEE60988.1};"]
[1054,"'CEBPG'",210,197,203.5,"05152///Tuberculosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity","GO:0042267///natural killer cell mediated cytotoxicity+++GO:0006955///immune response+++GO:0001889///liver development+++GO:0016071///mRNA metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0043353///enucleate erythrocyte differentiation+++GO:0045739///positive regulation of DNA repair+++GO:0045078///positive regulation of interferon-gamma biosynthetic process+++GO:0043388///positive regulation of DNA binding+++GO:0030183///B cell differentiation+++GO:0043433///negative regulation of DNA-binding transcription factor activity","IPR004827///Basic-leucine zipper domain","[CEBPG_HUMAN|Reviewed]RecName: Full=CCAAT/enhancer-binding protein gamma; Short=C/EBP gamma;"]
[10540,"'DCTN2'",2962,2273,2617.5,"04962///Vasopressin-regulated water reabsorption+++05016///Huntington's disease",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0070062///extracellular exosome+++GO:0005815///microtubule organizing center+++GO:0031982///vesicle+++GO:0005829///cytosol+++GO:0000776///kinetochore+++GO:0030426///growth cone+++GO:0005869///dynactin complex+++GO:0005813///centrosome+++GO:0030286///dynein complex+++GO:0016020///membrane","GO:0019901///protein kinase binding+++GO:0003774///motor activity+++GO:0030507///spectrin binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007017///microtubule-based process+++GO:0008283///cell proliferation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle+++GO:0071539///protein localization to centrosome+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007052///mitotic spindle organization+++GO:0032402///melanosome transport+++GO:0000086///G2/M transition of mitotic cell cycle","IPR028133///Dynamitin","[DCTN2_HUMAN|Reviewed]RecName: Full=Dynactin subunit 2; AltName: Full=50 kDa dynein-associated polypeptide; AltName: Full=Dynactin complex 50 kDa subunit; Short=DCTN-50; AltName: Full=p50 dynamitin;+++[A8K8J9_HUMAN|Unreviewed]SubName: Full=Dynactin 2 (P50), isoform CRA_b {ECO:0000313|EMBL:EAW97028.1}; SubName: Full=cDNA FLJ31120 fis, clone IMR322000730, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG51555.1}; SubName: Full=cDNA FLJ77785 {ECO:0000313|EMBL:BAF85053.1};+++[B3KTX4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38923 fis, clone NT2NE2011823, highly similar to Dynactin subunit 2 {ECO:0000313|EMBL:BAG53236.1};+++[F8VRV7_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448606}; Flags: Fragment;+++[F8VW18_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449855}; Flags: Fragment;+++[F8VX93_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000449710}; Flags: Fragment;+++[F8W0U6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447553};+++[F8W1I6_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000446964};+++[H0YHL1_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000447308}; Flags: Fragment;+++[H0YI98_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 2 {ECO:0000313|Ensembl:ENSP00000448937}; Flags: Fragment;+++[V9HW58_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 77 {ECO:0000313|EMBL:ACI46007.1};"]
[10541,"'ANP32B'",683,549,616,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0070063///RNA polymerase binding+++GO:0042393///histone binding+++GO:0005515///protein binding","GO:0046827///positive regulation of protein export from nucleus+++GO:0021591///ventricular system development+++GO:0001944///vasculature development+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0048839///inner ear development+++GO:0045596///negative regulation of cell differentiation+++GO:0006334///nucleosome assembly+++GO:0060021///roof of mouth development","IPR001611///Leucine-rich repeat+++IPR003603///U2A'/phosphoprotein 32 family A, C-terminal+++IPR032675///Leucine-rich repeat domain superfamily","[AN32B_HUMAN|Reviewed]RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member B; AltName: Full=Acidic protein rich in leucines; AltName: Full=Putative HLA-DR-associated protein I-2; Short=PHAPI2; AltName: Full=Silver-stainable protein SSP29;"]
[10542,"'LAMTOR5'",486,448,467,"05161///Hepatitis B+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0071986///Ragulator complex+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071230///cellular response to amino acid stimulus+++GO:0009615///response to virus+++GO:0043066///negative regulation of apoptotic process+++GO:0008361///regulation of cell size+++GO:0016241///regulation of macroautophagy+++GO:0032008///positive regulation of TOR signaling+++GO:0061462///protein localization to lysosome+++GO:0007050///cell cycle arrest+++GO:0019079///viral genome replication","IPR024135///Ragulator complex protein LAMTOR5","[LTOR5_HUMAN|Reviewed]RecName: Full=Ragulator complex protein LAMTOR5; AltName: Full=Hepatitis B virus X-interacting protein; Short=HBV X-interacting protein; Short=HBX-interacting protein; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5;+++[A0A0C4DGV4_HUMAN|Unreviewed]SubName: Full=Hepatitis B virus x interacting protein {ECO:0000313|EMBL:EAW56447.1}; SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000480529};+++[E9PLX3_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000435085};+++[R4GMU8_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR5 {ECO:0000313|Ensembl:ENSP00000473357};"]
[10544,"'PROCR'",1175,893,1034,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface","GO:0038023///signaling receptor activity+++GO:0005515///protein binding","GO:0050819///negative regulation of coagulation+++GO:0007599///hemostasis+++GO:0007596///blood coagulation","IPR011162///MHC classes I/II-like antigen recognition protein+++IPR015669///Endothelial protein C receptor+++IPR011161///MHC class I-like antigen recognition-like+++IPR037055///MHC class I-like antigen recognition-like superfamily","[EPCR_HUMAN|Reviewed]RecName: Full=Endothelial protein C receptor; AltName: Full=Activated protein C receptor; Short=APC receptor; AltName: Full=Endothelial cell protein C receptor; AltName: CD_antigen=CD201; Flags: Precursor;+++[A0A0U1RQQ4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489117}; Flags: Fragment;+++[A0A0U1RRC4_HUMAN|Unreviewed]SubName: Full=Endothelial protein C receptor {ECO:0000313|Ensembl:ENSP00000489456}; Flags: Fragment;"]
[10548,"'TM9SF1'",2335,2070,2202.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0000421///autophagosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005764///lysosome+++GO:0016021///integral component of membrane",null,"GO:0072657///protein localization to membrane+++GO:0006914///autophagy","IPR004240///Nonaspanin (TM9SF)","[TM9S1_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 1; AltName: Full=MP70 protein family member; Short=hMP70; Flags: Precursor;+++[B4E3A9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PJC4_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PJM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PL78_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PMQ9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[E9PNW2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PP24_HUMAN|Unreviewed]SubName: Full=Transmembrane 9 superfamily member 1 {ECO:0000313|Ensembl:ENSP00000436486}; Flags: Fragment;+++[E9PQY7_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[E9PS99_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079}; Flags: Fragment;+++[G3V1B9_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[10549,"'PRDX4'",1154,895,1024.5,"04214///Apoptosis - fly",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0005623///cell+++GO:0005790///smooth endoplasmic reticulum+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0004601///peroxidase activity+++GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity+++GO:0051920///peroxiredoxin activity+++GO:0016209///antioxidant activity+++GO:0008379///thioredoxin peroxidase activity","GO:0007252///I-kappaB phosphorylation+++GO:0045454///cell redox homeostasis+++GO:0072593///reactive oxygen species metabolic process+++GO:0042744///hydrogen peroxide catabolic process+++GO:0098869///cellular oxidant detoxification+++GO:0019471///4-hydroxyproline metabolic process+++GO:0006979///response to oxidative stress+++GO:2000255///negative regulation of male germ cell proliferation+++GO:0022417///protein maturation by protein folding+++GO:0008584///male gonad development+++GO:0043312///neutrophil degranulation+++GO:0007283///spermatogenesis+++GO:0055114///oxidation-reduction process+++GO:0030198///extracellular matrix organization","IPR036249///Thioredoxin-like superfamily+++IPR000866///Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant+++IPR019479///Peroxiredoxin, C-terminal+++IPR013766///Thioredoxin domain+++IPR024706///Peroxiredoxin, AhpC-type","[PRDX4_HUMAN|Reviewed]RecName: Full=Peroxiredoxin-4; EC=1.11.1.15 {ECO:0000269|PubMed:21916849, ECO:0000269|PubMed:9388242}; AltName: Full=Antioxidant enzyme AOE372; Short=AOE37-2; AltName: Full=Peroxiredoxin IV; Short=Prx-IV; AltName: Full=Thioredoxin peroxidase AO372; AltName: Full=Thioredoxin-dependent peroxide reductase A0372; Flags: Precursor;+++[A6NG45_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368635};+++[A6NJJ0_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000368654}; Flags: Fragment;+++[H7C3T4_HUMAN|Unreviewed]SubName: Full=Peroxiredoxin-4 {ECO:0000313|Ensembl:ENSP00000413736}; Flags: Fragment;+++[V9HW63_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 97n {ECO:0000313|EMBL:ACI45989.1}; SubName: Full=Peroxiredoxin 4 {ECO:0000313|EMBL:EAW98996.1};"]
[10550,"'ARL6IP5'",2523,2249,2386,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0005789///endoplasmic reticulum membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0002037///negative regulation of L-glutamate import across plasma membrane+++GO:0015813///L-glutamate transmembrane transport+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0032874///positive regulation of stress-activated MAPK cascade+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential","IPR004895///Prenylated rab acceptor PRA1","[PRAF3_HUMAN|Reviewed]RecName: Full=PRA1 family protein 3; AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 5; Short=ARL-6-interacting protein 5; Short=Aip-5; AltName: Full=Cytoskeleton-related vitamin A-responsive protein; AltName: Full=Dermal papilla-derived protein 11; AltName: Full=GTRAP3-18; AltName: Full=Glutamate transporter EAAC1-interacting protein; AltName: Full=JM5; AltName: Full=Prenylated Rab acceptor protein 2; AltName: Full=Protein JWa; AltName: Full=Putative MAPK-activating protein PM27;+++[A0A024R371_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[C9JQU6_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF33_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[F8WF90_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10552,"'ARPC1A'",1463,1210,1336.5,"05130///Pathogenic Escherichia coli infection+++04810///Regulation of actin cytoskeleton+++05100///Bacterial invasion of epithelial cells+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++05132///Salmonella infection+++05131///Shigellosis",{"$nulls":3},"GO:0005885///Arp2/3 protein complex+++GO:0035861///site of double-strand break+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0030036///actin cytoskeleton organization+++GO:0048013///ephrin receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0034314///Arp2/3 complex-mediated actin nucleation+++GO:0030833///regulation of actin filament polymerization+++GO:0061024///membrane organization","IPR017986///WD40-repeat-containing domain+++IPR036322///WD40-repeat-containing domain superfamily+++IPR001680///WD40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR017383///Actin-related protein 2/3 complex subunit 1+++IPR030140///Actin-related protein 2/3 complex subunit 1A","[ARC1A_HUMAN|Reviewed]RecName: Full=Actin-related protein 2/3 complex subunit 1A; AltName: Full=SOP2-like protein;+++[A0A0K0K1L3_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 307 {ECO:0000313|EMBL:ACV87209.1}; Flags: Fragment;+++[E9PF58_HUMAN|Unreviewed]SubName: Full=Actin-related protein 2/3 complex subunit 1A {ECO:0000313|Ensembl:ENSP00000408711};+++[Q75MY0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ARPC1A {ECO:0000313|EMBL:AAS00381.1}; Flags: Fragment;+++[V9HVZ6_HUMAN|Unreviewed]RecName: Full=Actin-related protein 2/3 complex subunit {ECO:0000256|PIRNR:PIRNR038093};"]
[10553,"'HTATIP2'",220,136,178,{"$nulls":4},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005635///nuclear envelope+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0045765///regulation of angiogenesis+++GO:0051170///import into nucleus+++GO:0030154///cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001525///angiogenesis+++GO:0006915///apoptotic process+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0016032///viral process+++GO:0043066///negative regulation of apoptotic process+++GO:0007275///multicellular organism development","IPR016040///NAD(P)-binding domain+++IPR036291///NAD(P)-binding domain superfamily","[HTAI2_HUMAN|Reviewed]RecName: Full=Oxidoreductase HTATIP2; EC=1.1.1.-; AltName: Full=30 kDa HIV-1 TAT-interacting protein; AltName: Full=HIV-1 TAT-interactive protein 2;+++[E9PI87_HUMAN|Unreviewed]SubName: Full=Oxidoreductase HTATIP2 {ECO:0000313|Ensembl:ENSP00000436729};"]
[10554,"'AGPAT1'",4793,4659,4726,"00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate+++R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity","GO:0006629///lipid metabolic process+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0001819///positive regulation of cytokine production+++GO:0031325///positive regulation of cellular metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process","IPR004552///1-acyl-sn-glycerol-3-phosphate acyltransferase+++IPR002123///Phospholipid/glycerol acyltransferase","[PLCA_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 1; Short=1-AGP acyltransferase 1; Short=1-AGPAT 1; AltName: Full=Lysophosphatidic acid acyltransferase alpha; Short=LPAAT-alpha; AltName: Full=Protein G15; Flags: Precursor;+++[A0A024RCV5_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};"]
[10555,"'AGPAT2'",1043,859,951,"00564///Glycerophospholipid metabolism+++04975///Fat digestion and absorption+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA+++R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase   Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0035579///specific granule membrane","GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity","GO:0042493///response to drug+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0008544///epidermis development+++GO:0016024///CDP-diacylglycerol biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0001819///positive regulation of cytokine production+++GO:0043312///neutrophil degranulation+++GO:0001961///positive regulation of cytokine-mediated signaling pathway+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","IPR002123///Phospholipid/glycerol acyltransferase+++IPR004552///1-acyl-sn-glycerol-3-phosphate acyltransferase","[PLCB_HUMAN|Reviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase beta; EC=2.3.1.51; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2; Short=1-AGP acyltransferase 2; Short=1-AGPAT 2; AltName: Full=Lysophosphatidic acid acyltransferase beta; Short=LPAAT-beta; Flags: Precursor;+++[A0A024R8F9_HUMAN|Unreviewed]SubName: Full=1-acylglycerol-3-phosphate O-acyltransferase 2 (Lysophosphatidic acid acyltransferase, beta), isoform CRA_b {ECO:0000313|EMBL:EAW88252.1}; SubName: Full=Testicular tissue protein Li 143 {ECO:0000313|EMBL:AEE61054.1};+++[A0A024R8I7_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q8WUW2_HUMAN|Unreviewed]RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267}; EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};+++[Q96IS9_HUMAN|Unreviewed]SubName: Full=AGPAT2 protein {ECO:0000313|EMBL:AAH07269.1}; Flags: Fragment;"]
[10556,"'RPP30'",156,168.98,162.49,"03013///RNA transport+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex+++GO:0030681///multimeric ribonuclease P complex+++GO:0000172///ribonuclease MRP complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004540///ribonuclease activity+++GO:0004526///ribonuclease P activity+++GO:0003723///RNA binding+++GO:0003824///catalytic activity+++GO:0016787///hydrolase activity","GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0001682///tRNA 5'-leader removal+++GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic","IPR016195///Polymerase/histidinol phosphatase-like+++IPR002738///RNase P subunit p30","[RPP30_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p30; Short=RNaseP protein p30; EC=3.1.26.5; AltName: Full=RNase P subunit 2;+++[Q5VU10_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000407972}; Flags: Fragment;+++[Q5VU11_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p30 {ECO:0000313|Ensembl:ENSP00000277882}; Flags: Fragment;"]
[10557,"'RPP38'",236,180,208,"03008///Ribosome biogenesis in eukaryotes+++03013///RNA transport",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005655///nucleolar ribonuclease P complex","GO:0004526///ribonuclease P activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0008033///tRNA processing+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090501///RNA phosphodiester bond hydrolysis","IPR029064///50S ribosomal protein L30e-like+++IPR004038///Ribosomal protein L7Ae/L30e/S12e/Gadd45","[RPP38_HUMAN|Reviewed]RecName: Full=Ribonuclease P protein subunit p38; Short=RNaseP protein p38; EC=3.1.26.5;+++[Q5VUC3_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000402635}; Flags: Fragment;+++[Q5VUC9_HUMAN|Unreviewed]SubName: Full=Ribonuclease P protein subunit p38 {ECO:0000313|Ensembl:ENSP00000367443};"]
[10558,"'SPTLC1'",681,703,692,"00600///Sphingolipid metabolism+++04071///Sphingolipid signaling pathway+++01100///Metabolic pathways+++04138///Autophagy - yeast","H00265///Hereditary sensory and autonomic neuropathy (HSAN)","M00099///Sphingosine biosynthesis+++M00094///Ceramide biosynthesis","R01281///Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)   Palmitoyl-CoA + L-Serine <=> 3-Dehydrosphinganine + CoA + CO2","GO:0017059///serine C-palmitoyltransferase complex+++GO:0016020///membrane+++GO:0035339///SPOTS complex+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0030170///pyridoxal phosphate binding+++GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0004758///serine C-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0030148///sphingolipid biosynthetic process+++GO:0009058///biosynthetic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0046511///sphinganine biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:0046513///ceramide biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0046512///sphingosine biosynthetic process+++GO:1904504///positive regulation of lipophagy","IPR015422///Pyridoxal phosphate-dependent transferase domain 1+++IPR004839///Aminotransferase, class I/classII+++IPR015424///Pyridoxal phosphate-dependent transferase+++IPR015421///Pyridoxal phosphate-dependent transferase, major domain","[SPTC1_HUMAN|Reviewed]RecName: Full=Serine palmitoyltransferase 1; EC=2.3.1.50; AltName: Full=Long chain base biosynthesis protein 1; Short=LCB 1; AltName: Full=Serine-palmitoyl-CoA transferase 1; Short=SPT 1; Short=SPT1;+++[A0A024R277_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase, long chain base subunit 1, isoform CRA_a {ECO:0000313|EMBL:EAW62805.1};+++[A0A2R8Y4S0_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000493933};+++[A0A2R8Y6A2_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495388};+++[A0A2R8Y763_HUMAN|Unreviewed]SubName: Full=Serine palmitoyltransferase 1 {ECO:0000313|Ensembl:ENSP00000495764}; Flags: Fragment;+++[L8E7V1_HUMAN|Unreviewed]SubName: Full=Alternative protein SPTLC1 {ECO:0000313|EMBL:CCQ43355.1};+++[Q6NUL7_HUMAN|Unreviewed]SubName: Full=SPTLC1 protein {ECO:0000313|EMBL:AAH68537.1};"]
[10559,"'SLC35A1'",68,53,60.5,"04137///Mitophagy - animal+++00970///Aminoacyl-tRNA biosynthesis+++04140///Autophagy - animal","H01392///Arthrogryposis, mental retardation, and seizures (AMRS)+++H00606///Early infantile epileptic encephalopathy+++H00119///Congenital disorders of glycosylation (CDG) type II","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03646///L-Arginine:tRNA(Arg) ligase (AMP-forming) ATP + L-Arginine + tRNA(Arg) <=> AMP + Diphosphate + L-Arginyl-tRNA(Arg)","GO:0005794///Golgi apparatus+++GO:0030173///integral component of Golgi membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0015136///sialic acid transmembrane transporter activity+++GO:0015165///pyrimidine nucleotide-sugar transmembrane transporter activity+++GO:0005456///CMP-N-acetylneuraminate transmembrane transporter activity","GO:0015782///CMP-N-acetylneuraminate transmembrane transport+++GO:0008643///carbohydrate transport+++GO:0015739///sialic acid transport+++GO:0090481///pyrimidine nucleotide-sugar transmembrane transport+++GO:0006464///cellular protein modification process+++GO:0005975///carbohydrate metabolic process","IPR007271///Nucleotide-sugar transporter","[S35A1_HUMAN|Reviewed]RecName: Full=CMP-sialic acid transporter; Short=CMP-SA-Tr; Short=CMP-Sia-Tr; AltName: Full=Solute carrier family 35 member A1;+++[A0A087WVM1_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|Ensembl:ENSP00000479535};+++[Q5W1L6_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65470.1};+++[Q5W1L7_HUMAN|Unreviewed]SubName: Full=CMP-sialic acid transporter {ECO:0000313|EMBL:CAH65469.1, ECO:0000313|Ensembl:ENSP00000358570};+++[Q6A0F2_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17781.1};+++[Q6A0F3_HUMAN|Unreviewed]SubName: Full=Mutated CMP-sialic acid transporter A1 {ECO:0000313|EMBL:CAH17780.1};"]
[1056,"'CEL'",132,125,128.5,"04975///Fat digestion and absorption+++01100///Metabolic pathways+++00561///Glycerolipid metabolism+++00100///Steroid biosynthesis+++04972///Pancreatic secretion","H00410///Maturity onset diabetes of the young (MODY)","M00098///Acylglycerol degradation","R01462///cholesterol ester acylhydrolase   Cholesterol ester + H2O <=> Cholesterol + Fatty acid+++R02687///1,2-diacyl-sn-glycerol acylhydrolase   1,2-Diacyl-sn-glycerol + H2O <=> 1-Acylglycerol + Fatty acid+++R02250///triacylglycerol acylhydrolase   Triacylglycerol + H2O <=> 1,2-Diacyl-sn-glycerol + Fatty acid","GO:0009986///cell surface+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0098793///presynapse+++GO:0005737///cytoplasm","GO:0004806///triglyceride lipase activity+++GO:0042043///neurexin family protein binding+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003824///catalytic activity+++GO:0038023///signaling receptor activity+++GO:0004771///sterol esterase activity+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0016787///hydrolase activity","GO:0006629///lipid metabolic process+++GO:0044258///intestinal lipid catabolic process+++GO:0007158///neuron cell-cell adhesion+++GO:0016042///lipid catabolic process+++GO:0044241///lipid digestion+++GO:0006707///cholesterol catabolic process+++GO:0097104///postsynaptic membrane assembly+++GO:0050804///modulation of chemical synaptic transmission+++GO:0018350///protein esterification+++GO:0030299///intestinal cholesterol absorption+++GO:0097105///presynaptic membrane assembly+++GO:0009062///fatty acid catabolic process+++GO:0046514///ceramide catabolic process+++GO:0048488///synaptic vesicle endocytosis+++GO:0030157///pancreatic juice secretion","IPR019826///Carboxylesterase type B, active site+++IPR002018///Carboxylesterase, type B+++IPR032059///Mucin-like domain+++IPR029058///Alpha/Beta hydrolase fold+++IPR019819///Carboxylesterase type B, conserved site+++IPR033560///Bile salt-activated lipase","[CEL_HUMAN|Reviewed]RecName: Full=Bile salt-activated lipase; Short=BAL; EC=3.1.1.13; EC=3.1.1.3; AltName: Full=Bile salt-stimulated lipase; Short=BSSL; AltName: Full=Bucelipase; AltName: Full=Carboxyl ester lipase; AltName: Full=Cholesterol esterase; AltName: Full=Pancreatic lysophospholipase; AltName: Full=Sterol esterase; Flags: Precursor;+++[B4DSX9_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};+++[O75612_HUMAN|Unreviewed]RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235}; EC=3.1.1.- {ECO:0000256|RuleBase:RU361235}; Flags: Fragment;+++[Q86SR3_HUMAN|Unreviewed]SubName: Full=CEL protein {ECO:0000313|EMBL:AAH42510.1};+++[X6R868_HUMAN|Unreviewed]SubName: Full=Bile salt-activated lipase {ECO:0000313|Ensembl:ENSP00000361151};"]
[10560,"'SLC19A2'",128,132,130,"04977///Vitamin digestion and absorption","H01231///Biotin-responsive basal ganglia disease (BBGD)+++H01183///Thiamine-responsive megaloblastic anemia (TRMA)+++H01565///Wernicke encephalopathy",null,null,"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0015234///thiamine transmembrane transporter activity+++GO:0005515///protein binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0090482///vitamin transmembrane transporter activity","GO:0042723///thiamine-containing compound metabolic process+++GO:0071934///thiamine transmembrane transport+++GO:0055085///transmembrane transport+++GO:0015888///thiamine transport+++GO:0035461///vitamin transmembrane transport+++GO:0015884///folic acid transport+++GO:0051180///vitamin transport","IPR002666///Reduced folate carrier+++IPR028338///Thiamine transporter 1+++IPR036259///MFS transporter superfamily","[S19A2_HUMAN|Reviewed]RecName: Full=Thiamine transporter 1; Short=ThTr-1; Short=ThTr1; AltName: Full=Solute carrier family 19 member 2; AltName: Full=Thiamine carrier 1; Short=TC1;+++[A0A024R8Y5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_c {ECO:0000313|EMBL:EAW90847.1}; SubName: Full=Solute carrier family 19 member 2 isoform 1 {ECO:0000313|EMBL:ALQ33992.1};+++[A0A024R928_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_a {ECO:0000313|EMBL:EAW90845.1}; SubName: Full=Solute carrier family 19 member 2 isoform 2 {ECO:0000313|EMBL:ALQ33993.1};+++[A0A2R8Y5B5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 (Thiamine transporter), member 2, isoform CRA_b {ECO:0000313|EMBL:EAW90844.1}; SubName: Full=Thiamine transporter 1 {ECO:0000313|Ensembl:ENSP00000494404};+++[B0FBR7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 19 thiamine transporter member 2 {ECO:0000313|EMBL:ABY51619.1}; Flags: Fragment;+++[E3UTN9_HUMAN|Unreviewed]SubName: Full=SLC19A2 solute carrier family 19 member 2 {ECO:0000313|EMBL:ADP24156.1}; Flags: Fragment;+++[I7BB09_HUMAN|Unreviewed]SubName: Full=Thiamnine trasporter protein {ECO:0000313|EMBL:AFO38177.2}; Flags: Fragment;+++[Q7Z7J1_HUMAN|Unreviewed]SubName: Full=Thiamine transporter THTR-1 {ECO:0000313|EMBL:AAP37965.1}; Flags: Fragment;"]
[10561,"'IFI44'",846,1030,938,{"$nulls":4},"GO:0005737///cytoplasm","GO:0005525///GTP binding","GO:0006955///immune response+++GO:0009617///response to bacterium+++GO:0009615///response to virus","IPR024644///Interferon-induced protein 44 family+++IPR006571///TLDc domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[IFI44_HUMAN|Reviewed]RecName: Full=Interferon-induced protein 44; Short=p44; AltName: Full=Microtubule-associated protein 44;+++[C9JUM8_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000399477}; Flags: Fragment;+++[H7C1F3_HUMAN|Unreviewed]SubName: Full=Interferon-induced protein 44 {ECO:0000313|Ensembl:ENSP00000400001}; Flags: Fragment;"]
[10562,"'OLFM4'",0,1,0.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0048471///perinuclear region of cytoplasm+++GO:0042582///azurophil granule+++GO:1904724///tertiary granule lumen+++GO:0030141///secretory granule+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion+++GO:0005576///extracellular region+++GO:0042581///specific granule+++GO:0035580///specific granule lumen","GO:0003824///catalytic activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0010939///regulation of necrotic cell death+++GO:0042981///regulation of apoptotic process+++GO:0051260///protein homooligomerization+++GO:0007155///cell adhesion+++GO:0050764///regulation of phagocytosis+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0043312///neutrophil degranulation+++GO:2000389///regulation of neutrophil extravasation","IPR003112///Olfactomedin-like domain+++IPR031221///Olfactomedin-4+++IPR011041///Soluble quinoprotein glucose/sorbosone dehydrogenase","[OLFM4_HUMAN|Reviewed]RecName: Full=Olfactomedin-4; Short=OLM4; AltName: Full=Antiapoptotic protein GW112; AltName: Full=G-CSF-stimulated clone 1 protein; Short=hGC-1; AltName: Full=hOLfD; Flags: Precursor;+++[A0A024QZ95_HUMAN|Unreviewed]SubName: Full=Olfactomedin 4, isoform CRA_a {ECO:0000313|EMBL:EAW52053.1};"]
[10564,"'ARFGEF2'",291,539,415,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0005829///cytosol+++GO:0005879///axonemal microtubule+++GO:0032279///asymmetric synapse+++GO:0048471///perinuclear region of cytoplasm+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0043197///dendritic spine+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005802///trans-Golgi network+++GO:0030054///cell junction+++GO:0032280///symmetric synapse+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0005856///cytoskeleton+++GO:0055037///recycling endosome+++GO:0030425///dendrite+++GO:0005815///microtubule organizing center+++GO:0005768///endosome+++GO:0042995///cell projection","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0050811///GABA receptor binding","GO:0032012///regulation of ARF protein signal transduction+++GO:0006887///exocytosis+++GO:0001881///receptor recycling+++GO:0006893///Golgi to plasma membrane transport+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport+++GO:0007032///endosome organization+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0035556///intracellular signal transduction","IPR032691///Guanine nucleotide exchange factor, N-terminal+++IPR016024///Armadillo-type fold+++IPR015403///Sec7, C-terminal+++IPR000904///Sec7 domain+++IPR023394///Sec7, C-terminal domain superfamily+++IPR035999///Sec7 domain superfamily+++IPR032629///Mon2, dimerisation and cyclophilin-binding domain","[BIG2_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Short=Brefeldin A-inhibited GEP 2; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2;+++[L8E9E5_HUMAN|Unreviewed]SubName: Full=Alternative protein ARFGEF2 {ECO:0000313|EMBL:CCQ43356.1};+++[Q59FR3_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 2 variant {ECO:0000313|EMBL:BAD92634.1}; Flags: Fragment;+++[Q86TH5_HUMAN|Unreviewed]SubName: Full=ARFGEF2 protein {ECO:0000313|EMBL:AAH50449.1}; Flags: Fragment;"]
[10565,"'ARFGEF1'",432,752,592,"04144///Endocytosis","H00270///Periventricular nodular heterotopia (PVNH)",null,null,"GO:0000139///Golgi membrane+++GO:0016363///nuclear matrix+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0005515///protein binding+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005096///GTPase activator activity+++GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0017022///myosin binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0051897///positive regulation of protein kinase B signaling+++GO:0090284///positive regulation of protein glycosylation in Golgi+++GO:0015031///protein transport+++GO:0007030///Golgi organization+++GO:0034260///negative regulation of GTPase activity+++GO:2000114///regulation of establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0010256///endomembrane system organization+++GO:0016192///vesicle-mediated transport+++GO:0090303///positive regulation of wound healing+++GO:0030837///negative regulation of actin filament polymerization+++GO:0006887///exocytosis+++GO:0032012///regulation of ARF protein signal transduction+++GO:0031175///neuron projection development","IPR015403///Sec7, C-terminal+++IPR035999///Sec7 domain superfamily+++IPR032629///Mon2, dimerisation and cyclophilin-binding domain+++IPR016024///Armadillo-type fold+++IPR032691///Guanine nucleotide exchange factor, N-terminal+++IPR000904///Sec7 domain+++IPR023394///Sec7, C-terminal domain superfamily","[BIG1_HUMAN|Reviewed]RecName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1; Short=Brefeldin A-inhibited GEP 1; AltName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1; AltName: Full=p200 ARF guanine nucleotide exchange factor; AltName: Full=p200 ARF-GEP1;+++[A0A024R7X0_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor guanine nucleotide-exchange factor 1(Brefeldin A-inhibited), isoform CRA_a {ECO:0000313|EMBL:EAW86936.1};+++[E5RHL7_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000430891}; Flags: Fragment;+++[E5RHZ1_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429560}; Flags: Fragment;+++[E5RIF2_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000428429}; Flags: Fragment;+++[E5RJN9_HUMAN|Unreviewed]SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|Ensembl:ENSP00000429002}; Flags: Fragment;"]
[10566,"'AKAP3'",11,16,13.5,{"$nulls":4},"GO:0031514///motile cilium+++GO:0035686///sperm fibrous sheath+++GO:0001669///acrosomal vesicle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0097228///sperm principal piece","GO:0051018///protein kinase A binding+++GO:0005515///protein binding","GO:0007340///acrosome reaction+++GO:0008104///protein localization+++GO:0007338///single fertilization+++GO:0001835///blastocyst hatching+++GO:0007178///transmembrane receptor protein serine/threonine kinase signaling pathway","IPR018292///A-kinase anchor 110kDa, C-terminal+++IPR020799///A-kinase anchor 110kDa+++IPR008382///SPHK1-interactor/A-kinase anchor 110kDa+++IPR018459///RII binding domain","[AKAP3_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 3; Short=AKAP-3; AltName: Full=A-kinase anchor protein 110 kDa; Short=AKAP 110; AltName: Full=Cancer/testis antigen 82; Short=CT82; AltName: Full=Fibrous sheath protein of 95 kDa; Short=FSP95; AltName: Full=Fibrousheathin I; AltName: Full=Fibrousheathin-1; AltName: Full=Protein kinase A-anchoring protein 3; Short=PRKA3; AltName: Full=Sperm oocyte-binding protein;+++[F5H2S4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000439382}; Flags: Fragment;+++[F5H7P4_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 3 {ECO:0000313|Ensembl:ENSP00000442376}; Flags: Fragment;+++[V9HWD4_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 159 {ECO:0000313|EMBL:ACJ13735.1};"]
[10567,"'RABAC1'",2531,2055,2293,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0005794///Golgi apparatus+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0070064///proline-rich region binding",null,"IPR004895///Prenylated rab acceptor PRA1","[PRAF1_HUMAN|Reviewed]RecName: Full=Prenylated Rab acceptor protein 1; AltName: Full=PRA1 family protein 1;+++[M0QXH1_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0QXU8_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};+++[M0R1H9_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107}; Flags: Fragment;+++[M0R3D4_HUMAN|Unreviewed]RecName: Full=PRA1 family protein {ECO:0000256|RuleBase:RU363107};"]
[10569,"'SLU7'",507.01,401.96,454.485,"03040///Spliceosome",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0071013///catalytic step 2 spliceosome+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0030628///pre-mRNA 3'-splice site binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0000386///second spliceosomal transesterification activity","GO:0000375///RNA splicing, via transesterification reactions+++GO:0006406///mRNA export from nucleus+++GO:0000380///alternative mRNA splicing, via spliceosome+++GO:0000389///mRNA 3'-splice site recognition+++GO:0034605///cellular response to heat+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0006886///intracellular protein transport","IPR021715///Pre-mRNA-splicing factor SLU7 domain+++IPR039974///Pre-mRNA-splicing factor SLU7","[SLU7_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor SLU7; Short=hSlu7;+++[A0A0C4DGD2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428362}; Flags: Fragment;+++[E5RGM7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000429990}; Flags: Fragment;+++[E5RK41_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor SLU7 {ECO:0000313|Ensembl:ENSP00000428943}; Flags: Fragment;"]
[10570,"'DPYSL4'",1367,1317,1342,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0031005///filamin binding","GO:0097485///neuron projection guidance+++GO:0070997///neuron death+++GO:0007399///nervous system development","IPR006680///Amidohydrolase-related+++IPR011059///Metal-dependent hydrolase, composite domain superfamily+++IPR011778///Hydantoinase/dihydropyrimidinase+++IPR032466///Metal-dependent hydrolase+++IPR030612///Dihydropyrimidinase-related protein 4","[DPYL4_HUMAN|Reviewed]RecName: Full=Dihydropyrimidinase-related protein 4; Short=DRP-4; AltName: Full=Collapsin response mediator protein 3; Short=CRMP-3; AltName: Full=UNC33-like phosphoprotein 4; Short=ULIP-4;+++[D3DRG7_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-like 4, isoform CRA_a {ECO:0000313|EMBL:EAW49133.1};+++[Q5T0Q6_HUMAN|Unreviewed]SubName: Full=Dihydropyrimidinase-related protein 4 {ECO:0000313|Ensembl:ENSP00000357616};"]
[10572,"'SIVA1'",237,159,198,"04115///p53 signaling pathway",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0001618///virus receptor activity+++GO:0046872///metal ion binding+++GO:0005175///CD27 receptor binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0008270///zinc ion binding","GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006915///apoptotic process+++GO:0046718///viral entry into host cell+++GO:0006924///activation-induced cell death of T cells+++GO:1901030///positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0016032///viral process+++GO:0097191///extrinsic apoptotic signaling pathway","IPR022773///Siva","[SIVA_HUMAN|Reviewed]RecName: Full=Apoptosis regulatory protein Siva; AltName: Full=CD27-binding protein; Short=CD27BP;+++[B4DTY2_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79449, highly similar to Apoptosis regulatory protein Siva {ECO:0000313|EMBL:BAG65628.1};+++[G3V3U1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451427};+++[G3V439_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451570}; Flags: Fragment;+++[H0YJN1_HUMAN|Unreviewed]SubName: Full=Apoptosis regulatory protein Siva {ECO:0000313|Ensembl:ENSP00000451823};"]
[10573,"'MRPL28'",1334,1007,1170.5,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005761///mitochondrial ribosome+++GO:0005739///mitochondrion","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:0006412///translation","IPR034704///L28p-like+++IPR026569///Ribosomal protein L28/L24+++IPR037147///Ribosomal protein L28/L24 superfamily","[RM28_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L28, mitochondrial; Short=L28mt; Short=MRP-L28; AltName: Full=Melanoma antigen p15; AltName: Full=Melanoma-associated antigen recognized by T-lymphocytes; AltName: Full=Mitochondrial large ribosomal subunit protein bL28m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[P13986_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:CAA34647.1};+++[Q9NRK2_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAF76751.1};+++[Q9UM95_HUMAN|Unreviewed]SubName: Full=p15 protein {ECO:0000313|EMBL:AAD14186.1}; Flags: Fragment;"]
[10574,"'CCT7'",3014,2489,2751.5,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0005874///microtubule+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0051082///unfolded protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0050821///protein stabilization+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0006457///protein folding","IPR027413///GroEL-like equatorial domain superfamily+++IPR027410///TCP-1-like chaperonin intermediate domain superfamily+++IPR002423///Chaperonin Cpn60/TCP-1 family+++IPR027409///GroEL-like apical domain superfamily+++IPR012720///T-complex protein 1, eta subunit+++IPR002194///Chaperonin TCP-1, conserved site+++IPR017998///Chaperone tailless complex polypeptide 1 (TCP-1)","[TCPH_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit eta; Short=TCP-1-eta; AltName: Full=CCT-eta; AltName: Full=HIV-1 Nef-interacting protein; Contains: RecName: Full=T-complex protein 1 subunit eta, N-terminally processed;+++[A0A0D9SG95_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[B7Z1C9_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[F8WAM2_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042}; Flags: Fragment;+++[F8WBP8_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};+++[Q6IBT3_HUMAN|Unreviewed]RecName: Full=T-complex protein 1 subunit eta {ECO:0000256|RuleBase:RU365042}; Short=TCP-1-eta {ECO:0000256|RuleBase:RU365042}; AltName: Full=CCT-eta {ECO:0000256|RuleBase:RU365042};"]
[10575,"'CCT4'",1677,1538,1607.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005832///chaperonin-containing T-complex+++GO:0044297///cell body+++GO:0070062///extracellular exosome+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0002199///zona pellucida receptor complex+++GO:0042470///melanosome+++GO:0005815///microtubule organizing center+++GO:0005813///centrosome+++GO:0005874///microtubule","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0051082///unfolded protein binding","GO:1904871///positive regulation of protein localization to Cajal body+++GO:0090666///scaRNA localization to Cajal body+++GO:0006457///protein folding+++GO:0050821///protein stabilization+++GO:0051973///positive regulation of telomerase activity+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0007339///binding of sperm to zona pellucida","IPR002423///Chaperonin Cpn60/TCP-1 family+++IPR027413///GroEL-like equatorial domain superfamily+++IPR017998///Chaperone tailless complex polypeptide 1 (TCP-1)+++IPR027409///GroEL-like apical domain superfamily+++IPR027410///TCP-1-like chaperonin intermediate domain superfamily+++IPR012717///T-complex protein 1, delta subunit+++IPR002194///Chaperonin TCP-1, conserved site","[TCPD_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit delta; Short=TCP-1-delta; AltName: Full=CCT-delta; AltName: Full=Stimulator of TAR RNA-binding;"]
[10576,"'CCT2'",1310,1068,1189,{"$nulls":4},"GO:0044297///cell body+++GO:0043209///myelin sheath+++GO:0005874///microtubule+++GO:0002199///zona pellucida receptor complex+++GO:0005829///cytosol+++GO:0035578///azurophil granule lumen+++GO:0005832///chaperonin-containing T-complex+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005524///ATP binding+++GO:0044183///protein binding involved in protein folding+++GO:0051082///unfolded protein binding","GO:0050821///protein stabilization+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0051973///positive regulation of telomerase activity+++GO:0051086///chaperone mediated protein folding independent of cofactor+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0090666///scaRNA localization to Cajal body+++GO:0007339///binding of sperm to zona pellucida+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0043312///neutrophil degranulation+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1901998///toxin transport+++GO:0006457///protein folding","IPR002423///Chaperonin Cpn60/TCP-1 family+++IPR017998///Chaperone tailless complex polypeptide 1 (TCP-1)+++IPR012716///T-complex protein 1, beta subunit+++IPR027410///TCP-1-like chaperonin intermediate domain superfamily+++IPR002194///Chaperonin TCP-1, conserved site+++IPR027413///GroEL-like equatorial domain superfamily+++IPR027409///GroEL-like apical domain superfamily","[TCPB_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit beta; Short=TCP-1-beta; AltName: Full=CCT-beta;+++[F5GWF6_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000441847};+++[F8VQ14_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit beta {ECO:0000313|Ensembl:ENSP00000450153};+++[V9HW96_HUMAN|Unreviewed]SubName: Full=Chaperonin containing TCP1, subunit 2 (Beta), isoform CRA_b {ECO:0000313|EMBL:EAW97229.1}; SubName: Full=Epididymis secretory sperm binding protein Li 100n {ECO:0000313|EMBL:ACI46043.1};"]
[10577,"'NPC2'",5204,4292,4748,"04142///Lysosome+++04979///Cholesterol metabolism","H00136///Niemann-Pick disease type C (NPC)",null,null,"GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome+++GO:0035578///azurophil granule lumen+++GO:0043202///lysosomal lumen+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0005623///cell","GO:0019899///enzyme binding+++GO:0017127///cholesterol transporter activity+++GO:0015485///cholesterol binding+++GO:0005515///protein binding","GO:0030301///cholesterol transport+++GO:0033344///cholesterol efflux+++GO:0046836///glycolipid transport+++GO:0015914///phospholipid transport+++GO:0032366///intracellular sterol transport+++GO:0008202///steroid metabolic process+++GO:0043312///neutrophil degranulation+++GO:0042632///cholesterol homeostasis+++GO:0006869///lipid transport+++GO:0034383///low-density lipoprotein particle clearance+++GO:0019747///regulation of isoprenoid metabolic process+++GO:0006629///lipid metabolic process+++GO:0009615///response to virus+++GO:0032367///intracellular cholesterol transport+++GO:0008203///cholesterol metabolic process","IPR014756///Immunoglobulin E-set+++IPR033916///Npc2 like, ML domain+++IPR039670///Sterol transport protein NPC2-like+++IPR003172///MD-2-related lipid-recognition domain","[NPC2_HUMAN|Reviewed]RecName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000312|HGNC:HGNC:14537}; AltName: Full=Epididymal secretory protein E1; AltName: Full=Human epididymis-specific protein 1; Short=He1 {ECO:0000303|PubMed:11125141, ECO:0000303|PubMed:8418812}; AltName: Full=Niemann-Pick disease type C2 protein {ECO:0000303|PubMed:17018531}; Flags: Precursor;+++[A0A024R6C0_HUMAN|Unreviewed]SubName: Full=Niemann-Pick disease, type C2, isoform CRA_a {ECO:0000313|EMBL:EAW81177.1};+++[E7EMS2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000412103};+++[G3V2V8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450887}; Flags: Fragment;+++[G3V3D1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451180}; Flags: Fragment;+++[G3V3E8_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451206};+++[H0YIZ1_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000450502}; Flags: Fragment;+++[H0YJE2_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000451314}; Flags: Fragment;+++[J3KMY5_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 2 {ECO:0000313|Ensembl:ENSP00000238633};"]
[10579,"'TACC2'",290,273,281.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0035257///nuclear hormone receptor binding","GO:0007052///mitotic spindle organization+++GO:0021987///cerebral cortex development+++GO:0008283///cell proliferation+++GO:0000226///microtubule cytoskeleton organization","IPR007707///Transforming acidic coiled-coil-containing protein, C-terminal+++IPR039915///Alp7/TACC","[TACC2_HUMAN|Reviewed]RecName: Full=Transforming acidic coiled-coil-containing protein 2; AltName: Full=Anti-Zuai-1; Short=AZU-1;+++[A0A0U1RRM9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489610}; Flags: Fragment;+++[B2RWP4_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI50628.1};+++[B7ZMJ9_HUMAN|Unreviewed]SubName: Full=TACC2 protein {ECO:0000313|EMBL:AAI44600.1};+++[D6RAA5_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422815};+++[E7EMZ9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000427618};+++[E9PBC6_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000424467};+++[E9PGB3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000420967}; Flags: Fragment;+++[H0Y8P9_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000421702}; Flags: Fragment;+++[H0Y911_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422725}; Flags: Fragment;+++[H0Y954_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423069}; Flags: Fragment;+++[H0Y9C3_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000423764}; Flags: Fragment;+++[H0Y9Y7_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000425525}; Flags: Fragment;+++[H0YA73_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000426303}; Flags: Fragment;+++[Q4VXL4_HUMAN|Unreviewed]SubName: Full=HCG41426, isoform CRA_c {ECO:0000313|EMBL:EAW49324.1}; SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357997};+++[Q4VXL8_HUMAN|Unreviewed]SubName: Full=Transforming acidic coiled-coil-containing protein 2 {ECO:0000313|Ensembl:ENSP00000357995};"]
[10580,"'SORBS1'",119,319,219,"03320///PPAR signaling pathway+++04910///Insulin signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005899///insulin receptor complex+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0045121///membrane raft+++GO:0005924///cell-substrate adherens junction+++GO:0005813///centrosome+++GO:0005912///adherens junction+++GO:0016020///membrane+++GO:0005915///zonula adherens+++GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016363///nuclear matrix+++GO:0005913///cell-cell adherens junction","GO:0005515///protein binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0005158///insulin receptor binding+++GO:0008092///cytoskeletal protein binding+++GO:0003779///actin binding","GO:0048041///focal adhesion assembly+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0046326///positive regulation of glucose import+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0008286///insulin receptor signaling pathway+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0043149///stress fiber assembly+++GO:0032869///cellular response to insulin stimulus+++GO:0006936///muscle contraction+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0007160///cell-matrix adhesion+++GO:0007015///actin filament organization","IPR001452///SH3 domain+++IPR035611///c-Cbl associated protein, SH3 domain 2+++IPR028506///Sorbin and SH3 domain-containing protein+++IPR035606///c-Cbl associated protein, SH3 domain+++IPR003127///SoHo domain+++IPR035610///c-Cbl associated protein, SH3 domain 1+++IPR036028///SH3-like domain superfamily","[SRBS1_HUMAN|Reviewed]RecName: Full=Sorbin and SH3 domain-containing protein 1; AltName: Full=Ponsin; AltName: Full=SH3 domain protein 5; AltName: Full=SH3P12; AltName: Full=c-Cbl-associated protein; Short=CAP;+++[A0A0U1RQI5_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000489022}; Flags: Fragment;+++[B4DTX5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60072, highly similar to Homo sapiens sorbin and SH3 domain containing 1 (SORBS1), transcript variant 6, mRNA {ECO:0000313|EMBL:BAG62137.1};+++[D3DR43_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain containing 1, isoform CRA_e {ECO:0000313|EMBL:EAW50004.1};+++[Q5T925_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000360272}; Flags: Fragment;+++[S4R303_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000473813}; Flags: Fragment;+++[S4R406_HUMAN|Unreviewed]SubName: Full=Sorbin and SH3 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000474932}; Flags: Fragment;"]
[10581,"'IFITM2'",1944.01,1525,1734.505,"04662///B cell receptor signaling pathway","H00506///Osteogenesis imperfecta",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0032991///protein-containing complex+++GO:0005886///plasma membrane",null,"GO:0035456///response to interferon-beta+++GO:0035455///response to interferon-alpha+++GO:0051607///defense response to virus+++GO:0009615///response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0006955///immune response+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0034341///response to interferon-gamma+++GO:0046597///negative regulation of viral entry into host cell+++GO:0002376///immune system process","IPR007593///CD225/Dispanin family","[IFM2_HUMAN|Reviewed]RecName: Full=Interferon-induced transmembrane protein 2; AltName: Full=Dispanin subfamily A member 2c; Short=DSPA2c; AltName: Full=Interferon-inducible protein 1-8D;+++[E9PQN9_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000434443};+++[H0YCL2_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000431850}; Flags: Fragment;+++[H7BYV1_HUMAN|Unreviewed]SubName: Full=Interferon-induced transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000382712}; Flags: Fragment;+++[Q6IBB0_HUMAN|Unreviewed]SubName: Full=IFITM2 protein {ECO:0000313|EMBL:CAG33175.1}; SubName: Full=Interferon induced transmembrane protein 2 (1-8D) {ECO:0000313|EMBL:AAP88861.1};"]
[10584,"'COLEC10'",0,1,0.5,"04380///Osteoclast differentiation+++04060///Cytokine-cytokine receptor interaction","H01887///3MC syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005794///Golgi apparatus","GO:0048029///monosaccharide binding+++GO:0004252///serine-type endopeptidase activity+++GO:0005537///mannose binding+++GO:0042056///chemoattractant activity+++GO:0030246///carbohydrate binding","GO:0006956///complement activation+++GO:0050918///positive chemotaxis+++GO:1904888///cranial skeletal system development+++GO:0001867///complement activation, lectin pathway+++GO:0006508///proteolysis","IPR033990///Collectin, C-type lectin-like domain+++IPR016187///C-type lectin fold+++IPR008160///Collagen triple helix repeat+++IPR018378///C-type lectin, conserved site+++IPR001304///C-type lectin-like+++IPR016186///C-type lectin-like/link domain superfamily","[COL10_HUMAN|Reviewed]RecName: Full=Collectin-10; AltName: Full=Collectin liver protein 1; Short=CL-L1; AltName: Full=Collectin-34; Short=CL-34; Flags: Precursor;+++[A0A024R9J3_HUMAN|Unreviewed]SubName: Full=Collectin sub-family member 10 (C-type lectin), isoform CRA_a {ECO:0000313|EMBL:EAW91980.1};"]
[10585,"'POMT1'",931,1080.23,1005.615,"00515///Mannose type O-glycan biosynthesis+++00514///Other types of O-glycan biosynthesis+++01100///Metabolic pathways","H01960///Muscular dystrophy-dystroglycanopathy type B+++H00593///Limb-girdle muscular dystrophy (LGMD)+++H00120///Muscular dystrophy-dystroglycanopathy type A+++H01959///Muscular dystrophy-dystroglycanopathy type C+++H00590///Congenital muscular dystrophies (CMD/MDC)",null,"R07620///Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + G13027+++R04072///dolichyl-beta-D-mannosyl-phosphate:protein-serine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-serine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-serinyl-[protein]+++R11399///dolichyl-beta-D-mannosyl-phosphate:protein-threonine O-D-mannosyltransferase   Dolichyl phosphate D-mannose + [Protein]-L-threonine <=> Dolichyl phosphate + 3-O-(alpha-D-Mannosyl)-L-threonyl-[protein]","GO:0016021///integral component of membrane+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0000030///mannosyltransferase activity+++GO:0004169///dolichyl-phosphate-mannose-protein mannosyltransferase activity+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0097502///mannosylation+++GO:0030198///extracellular matrix organization+++GO:0035269///protein O-linked mannosylation+++GO:0007275///multicellular organism development+++GO:0006486///protein glycosylation+++GO:1904100///positive regulation of protein O-linked glycosylation+++GO:0005975///carbohydrate metabolic process+++GO:0006493///protein O-linked glycosylation","IPR036300///Mir domain superfamily+++IPR016093///MIR motif+++IPR032421///Protein O-mannosyl-transferase, C-terminal four TM domain+++IPR027005///Glycosyltransferase 39-like+++IPR003342///Glycosyl transferase family 39/83","[POMT1_HUMAN|Reviewed]RecName: Full=Protein O-mannosyl-transferase 1; EC=2.4.1.109; AltName: Full=Dolichyl-phosphate-mannose--protein mannosyltransferase 1;+++[A0A140VKE0_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 57p {ECO:0000313|EMBL:AEE61277.1};+++[A0A1L6C7Q4_HUMAN|Unreviewed]SubName: Full=Truncated O-mannosyl-transferase 1 variant SV3DEL {ECO:0000313|EMBL:APQ46216.1}; EC=2.4.1.109 {ECO:0000313|EMBL:APQ46216.1};+++[A0A1V1FTP4_HUMAN|Unreviewed]SubName: Full=POMT1 protein {ECO:0000313|EMBL:BAX07485.1};+++[Q5JSZ6_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000390737}; Flags: Fragment;+++[Q5JT02_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000361294}; Flags: Fragment;+++[Q5JT03_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000395060}; Flags: Fragment;+++[Q5JT04_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000405149}; Flags: Fragment;+++[Q5JT05_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000402083}; Flags: Fragment;+++[Q5JT07_HUMAN|Unreviewed]SubName: Full=Protein O-mannosyl-transferase 1 {ECO:0000313|Ensembl:ENSP00000403736}; Flags: Fragment;"]
[10586,"'MAB21L2'",769,1090,929.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0043010///camera-type eye development+++GO:0010172///embryonic body morphogenesis+++GO:0007399///nervous system development+++GO:0001654///eye development+++GO:0008284///positive regulation of cell proliferation","IPR024810///Mab-21 domain+++IPR020950///Protein male abnormal 21/21-like 2+++IPR000772///Ricin B, lectin domain","[MB212_HUMAN|Reviewed]RecName: Full=Protein mab-21-like 2;"]
[10587,"'TXNRD2'",361.63,280,320.815,"05225///Hepatocellular carcinoma+++05200///Pathways in cancer+++00450///Selenocompound metabolism","H00256///Familial glucocorticoid deficiency (FGD)",null,"R09372///methaneselenol:NADP+ oxidoreductase   2 NADPH + 2 H+ + Methylselenic acid <=> 2 NADP+ + 2 H2O + Methaneselenol+++R03596///hydrogen selenide:NADP+ oxidoreductase   Hydrogen selenide + 3 NADP+ + 3 H2O <=> Selenite + 3 NADPH + 5 H+","GO:0005623///cell+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0016668///oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor+++GO:0050660///flavin adenine dinucleotide binding+++GO:0004791///thioredoxin-disulfide reductase activity+++GO:0009055///electron transfer activity","GO:0034599///cellular response to oxidative stress+++GO:0022900///electron transport chain+++GO:0055114///oxidation-reduction process+++GO:0045454///cell redox homeostasis+++GO:0098869///cellular oxidant detoxification+++GO:0000305///response to oxygen radical","IPR006338///Thioredoxin/glutathione reductase selenoprotein+++IPR016156///FAD/NAD-linked reductase, dimerisation domain superfamily+++IPR023753///FAD/NAD(P)-binding domain+++IPR036188///FAD/NAD(P)-binding domain superfamily+++IPR004099///Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain+++IPR012999///Pyridine nucleotide-disulphide oxidoreductase, class I, active site+++IPR001100///Pyridine nucleotide-disulphide oxidoreductase, class I","[TRXR2_HUMAN|Reviewed]RecName: Full=Thioredoxin reductase 2, mitochondrial; EC=1.8.1.9; AltName: Full=Selenoprotein Z; Short=SelZ; AltName: Full=TR-beta; AltName: Full=Thioredoxin reductase TR3; Flags: Precursor;+++[A0A096LNY7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485290}; Flags: Fragment;+++[A0A096LP96_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485466};+++[A0A096LPB7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485499};+++[A0A096LPD9_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485543};+++[A0A096LPH4_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485603};+++[A0A096LPK7_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000485665};+++[A0A0U1RQX0_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000489208}; Flags: Fragment;+++[A0A182DWF2_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383362};+++[A0A182DWF3_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383363};+++[A4FTY4_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAH99923.1};+++[D3YTF8_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000383369};+++[E7EWK1_HUMAN|Unreviewed]SubName: Full=Thioredoxin reductase 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000334451};+++[Q17RE6_HUMAN|Unreviewed]SubName: Full=TXNRD2 protein {ECO:0000313|EMBL:AAI17355.1};"]
[10588,"'MTHFS'",69,57,63,"00670///One carbon pool by folate+++01100///Metabolic pathways",null,null,"R02301///5-Formyltetrahydrofolate cyclo-ligase (ADP-forming)   ATP + Folinic acid + H+ <=> ADP + Orthophosphate + 5,10-Methenyltetrahydrofolate","GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005759///mitochondrial matrix","GO:0005542///folic acid binding+++GO:0005524///ATP binding+++GO:0030272///5-formyltetrahydrofolate cyclo-ligase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016874///ligase activity","GO:0006536///glutamate metabolic process+++GO:0046653///tetrahydrofolate metabolic process+++GO:0015942///formate metabolic process+++GO:0046655///folic acid metabolic process+++GO:0046657///folic acid catabolic process+++GO:0009396///folic acid-containing compound biosynthetic process+++GO:0035999///tetrahydrofolate interconversion","IPR002698///5-formyltetrahydrofolate cyclo-ligase+++IPR024185///5-formyltetrahydrofolate cyclo-ligase-like domain superfamily+++IPR037171///NagB/RpiA transferase-like","[MTHFS_HUMAN|Reviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase; EC=6.3.3.2; AltName: Full=5,10-methenyl-tetrahydrofolate synthetase; Short=MTHFS; Short=Methenyl-THF synthetase;+++[A0A0U1RQM3_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279};+++[H3BMB9_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454318}; Flags: Fragment;+++[H3BN04_HUMAN|Unreviewed]SubName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000313|Ensembl:ENSP00000454626};+++[Q96EE9_HUMAN|Unreviewed]RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279}; EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279}; Flags: Fragment;"]
[10589,"'DRAP1'",921,633,777,{"$nulls":4},"GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003714///transcription corepressor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0042802///identical protein binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR009072///Histone-fold+++IPR003958///Transcription factor CBF/NF-Y/archaeal histone domain","[NC2A_HUMAN|Reviewed]RecName: Full=Dr1-associated corepressor; AltName: Full=Dr1-associated protein 1; AltName: Full=Negative cofactor 2-alpha; Short=NC2-alpha;+++[C9JCC6_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000366190};+++[E9PMW2_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437287};+++[E9PNC7_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000437225}; Flags: Fragment;+++[E9PQX9_HUMAN|Unreviewed]SubName: Full=Dr1-associated corepressor {ECO:0000313|Ensembl:ENSP00000432445};"]
[1059,"'CENPB'",2187,1885,2036,{"$nulls":4},"GO:0016604///nuclear body+++GO:0031618///nuclear pericentric heterochromatin+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0005634///nucleus","GO:0003696///satellite DNA binding+++GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0019237///centromeric DNA binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding",null,"IPR007889///DNA binding HTH domain, Psq-type+++IPR009057///Homeobox-like domain superfamily+++IPR006600///HTH CenpB-type DNA-binding domain+++IPR015115///Centromere protein CENP-B, C-terminal domain+++IPR004875///DDE superfamily endonuclease domain+++IPR033062///Major centromere autoantigen B+++IPR034882///CENP-B, dimerisation domain superfamily","[CENPB_HUMAN|Reviewed]RecName: Full=Major centromere autoantigen B; AltName: Full=Centromere protein B; Short=CENP-B;"]
[10591,"'DNPH1'",400,239,319.5,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0070694///deoxyribonucleoside 5'-monophosphate N-glycosidase activity+++GO:0042803///protein homodimerization activity+++GO:0016799///hydrolase activity, hydrolyzing N-glycosyl compounds+++GO:0016798///hydrolase activity, acting on glycosyl bonds","GO:0008152///metabolic process+++GO:0009159///deoxyribonucleoside monophosphate catabolic process+++GO:0030855///epithelial cell differentiation+++GO:0009116///nucleoside metabolic process+++GO:0006195///purine nucleotide catabolic process+++GO:0008283///cell proliferation+++GO:0009117///nucleotide metabolic process+++GO:0030307///positive regulation of cell growth","IPR007710///Nucleoside 2-deoxyribosyltransferase+++IPR028607///2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1","[DNPH1_HUMAN|Reviewed]RecName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036}; EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_03036, ECO:0000269|PubMed:24260472, ECO:0000269|PubMed:25108359}; AltName: Full=c-Myc-responsive protein RCL {ECO:0000255|HAMAP-Rule:MF_03036};+++[H0Y8X4_HUMAN|Unreviewed]SubName: Full=2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000313|Ensembl:ENSP00000422440}; Flags: Fragment;"]
[10592,"'SMC2'",143,154,148.5,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0000793///condensed chromosome+++GO:0000796///condensin complex+++GO:0070062///extracellular exosome+++GO:0005730///nucleolus+++GO:0000228///nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0003697///single-stranded DNA binding+++GO:0005524///ATP binding+++GO:0046982///protein heterodimerization activity","GO:0051301///cell division+++GO:0045132///meiotic chromosome segregation+++GO:0007076///mitotic chromosome condensation+++GO:0010032///meiotic chromosome condensation+++GO:0051383///kinetochore organization","IPR010935///SMCs flexible hinge+++IPR027120///Smc2, ATP-binding cassette domain+++IPR036277///SMCs flexible hinge superfamily+++IPR024704///Structural maintenance of chromosomes protein+++IPR003395///RecF/RecN/SMC, N-terminal+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[SMC2_HUMAN|Reviewed]RecName: Full=Structural maintenance of chromosomes protein 2; Short=SMC protein 2; Short=SMC-2; AltName: Full=Chromosome-associated protein E; Short=hCAP-E; AltName: Full=XCAP-E homolog;+++[A0A024R158_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[A8K984_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B3KMB1_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[B7ZLZ7_HUMAN|Unreviewed]RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};+++[Q05BV1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH32705.1}; Flags: Fragment;+++[Q05D74_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH17845.1}; Flags: Fragment;+++[Q6IPS5_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH71750.1}; Flags: Fragment;+++[Q7Z2X1_HUMAN|Unreviewed]SubName: Full=SMC2 protein {ECO:0000313|EMBL:AAH55081.1}; Flags: Fragment;"]
[10594,"'PRPF8'",4609,5091,4850,"03040///Spliceosome","H00527///Retinitis pigmentosa (RP)","M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00355///Spliceosome, 35S U5-snRNP",null,"GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005682///U5 snRNP+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0071005///U2-type precatalytic spliceosome+++GO:0030532///small nuclear ribonucleoprotein complex+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0016020///membrane","GO:0000386///second spliceosomal transesterification activity+++GO:0097157///pre-mRNA intronic binding+++GO:0030623///U5 snRNA binding+++GO:0003723///RNA binding+++GO:0030620///U2 snRNA binding+++GO:0017070///U6 snRNA binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0030619///U1 snRNA binding+++GO:0005515///protein binding","GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0071222///cellular response to lipopolysaccharide+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0006397///mRNA processing+++GO:0071356///cellular response to tumor necrosis factor+++GO:0008380///RNA splicing","IPR019582///RNA recognition motif, spliceosomal PrP8+++IPR019581///Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding+++IPR021983///PRP8 domain IV core+++IPR012592///PROCN domain+++IPR019580///Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding+++IPR027652///Pre-mRNA-processing-splicing factor 8+++IPR037518///MPN domain+++IPR012591///PRO8NT domain+++IPR012337///Ribonuclease H-like superfamily+++IPR012984///PROCT domain+++IPR000555///JAB1/MPN/MOV34 metalloenzyme domain","[PRP8_HUMAN|Reviewed]RecName: Full=Pre-mRNA-processing-splicing factor 8; AltName: Full=220 kDa U5 snRNP-specific protein; AltName: Full=PRP8 homolog; AltName: Full=Splicing factor Prp8; AltName: Full=p220;+++[I3L0J9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000458151}; Flags: Fragment;+++[I3L1T8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000459095}; Flags: Fragment;+++[I3L3Z8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-processing-splicing factor 8 {ECO:0000313|Ensembl:ENSP00000460849}; Flags: Fragment;"]
[10597,"'TRAPPC2B'",51.83,29.51,40.67,null,"H00760///Spondyloepiphyseal dysplasia tarda",null,null,"GO:0005634///nucleus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0008134///transcription factor binding+++GO:0044325///ion channel binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport","IPR011012///Longin-like domain superfamily+++IPR006722///Trafficking protein particle complex subunit 2","[TPC2A_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2; AltName: Full=Sedlin;+++[TPC2B_HUMAN|diamond]RecName: Full=Trafficking protein particle complex subunit 2B; AltName: Full=MBP-1-interacting protein 2A; Short=MIP-2A;+++[TPPC2_BOVIN|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_CANLF|diamond]RecName: Full=Trafficking protein particle complex subunit 2;+++[TPPC2_PONAB|diamond]RecName: Full=Trafficking protein particle complex subunit 2;"]
[10598,"'AHSA1'",1152,760,956,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0051087///chaperone binding+++GO:0051879///Hsp90 protein binding+++GO:0001671///ATPase activator activity+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0032781///positive regulation of ATPase activity","IPR015310///Activator of Hsp90 ATPase, N-terminal+++IPR039981///Activator of 90kDa heat shock protein ATPase-like+++IPR023393///START-like domain superfamily+++IPR036338///Activator of Hsp90 ATPase, Aha1+++IPR013538///Activator of Hsp90 ATPase homologue 1-like","[AHSA1_HUMAN|Reviewed]RecName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1; Short=AHA1; AltName: Full=p38;+++[G3V3W9_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451467};+++[G3V438_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451569}; Flags: Fragment;+++[H0YJ63_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000450890}; Flags: Fragment;+++[H0YJG7_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000451475}; Flags: Fragment;+++[H0YJU2_HUMAN|Unreviewed]SubName: Full=Activator of 90 kDa heat shock protein ATPase homolog 1 {ECO:0000313|Ensembl:ENSP00000452127}; Flags: Fragment;"]
[1060,"'CENPC'",44,58,51,{"$nulls":4},"GO:0031618///nuclear pericentric heterochromatin+++GO:0000776///kinetochore+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0090543///Flemming body+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0030496///midbody+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0016604///nuclear body+++GO:0032154///cleavage furrow","GO:0003677///DNA binding+++GO:0019237///centromeric DNA binding","GO:0007059///chromosome segregation+++GO:0000278///mitotic cell cycle+++GO:0051455///attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation+++GO:0051382///kinetochore assembly+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division","IPR028931///CENP-C, middle DNMT3B-binding domain+++IPR028052///Kinetochore assembly subunit CENP-C, N-terminal domain+++IPR025974///Mif2/CENP-C cupin domain+++IPR028386///Centromere protein C/Mif2/cnp3+++IPR011051///RmlC-like cupin domain superfamily+++IPR014710///RmlC-like jelly roll fold","[CENPC_HUMAN|Reviewed]RecName: Full=Centromere protein C; Short=CENP-C; AltName: Full=Centromere autoantigen C; AltName: Full=Centromere protein C 1; Short=CENP-C 1; AltName: Full=Interphase centromere complex protein 7;"]
[10600,"'USP16'",286,252,269,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0035578///azurophil granule lumen+++GO:0070062///extracellular exosome+++GO:0044297///cell body+++GO:0005829///cytosol+++GO:0005813///centrosome+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0005634///nucleus+++GO:0002199///zona pellucida receptor complex+++GO:0045111///intermediate filament cytoskeleton+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005874///microtubule+++GO:0034774///secretory granule lumen","GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0042393///histone binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0044183///protein binding involved in protein folding+++GO:0003713///transcription coactivator activity+++GO:0008270///zinc ion binding+++GO:0043130///ubiquitin binding+++GO:0045296///cadherin binding+++GO:0005524///ATP binding+++GO:0042623///ATPase activity, coupled+++GO:0004197///cysteine-type endopeptidase activity+++GO:0051082///unfolded protein binding","GO:0006457///protein folding+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0016578///histone deubiquitination+++GO:0045901///positive regulation of translational elongation+++GO:0000278///mitotic cell cycle+++GO:0046931///pore complex assembly+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061077///chaperone-mediated protein folding+++GO:0051726///regulation of cell cycle+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0051289///protein homotetramerization+++GO:0006351///transcription, DNA-templated+++GO:0043312///neutrophil degranulation+++GO:0051301///cell division+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006458///'de novo' protein folding+++GO:0050821///protein stabilization+++GO:1901998///toxin transport+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0140014///mitotic nuclear division+++GO:0016579///protein deubiquitination+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0007339///binding of sperm to zona pellucida","IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase+++IPR018200///Ubiquitin specific protease, conserved site+++IPR030849///Ubiquitin carboxyl-terminal hydrolase 16+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR001607///Zinc finger, UBP-type+++IPR028889///Ubiquitin specific protease domain","[UBP16_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; EC=3.4.19.12 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Deubiquitinating enzyme 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin thioesterase 16 {ECO:0000255|HAMAP-Rule:MF_03062}; AltName: Full=Ubiquitin-processing protease UBP-M; AltName: Full=Ubiquitin-specific-processing protease 16 {ECO:0000255|HAMAP-Rule:MF_03062};"]
[10602,"'CDC42EP3'",5268,7381,6324.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0012505///endomembrane system","GO:0005515///protein binding+++GO:0005519///cytoskeletal regulatory protein binding+++GO:0017049///GTP-Rho binding","GO:0008360///regulation of cell shape+++GO:0007165///signal transduction+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization","IPR029273///Cdc42 effector+++IPR000095///CRIB domain","[BORG2_HUMAN|Reviewed]RecName: Full=Cdc42 effector protein 3; AltName: Full=Binder of Rho GTPases 2; AltName: Full=MSE55-related Cdc42-binding protein;+++[C9J7F7_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000398062}; Flags: Fragment;+++[C9JEZ4_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000403298}; Flags: Fragment;+++[C9JKW5_HUMAN|Unreviewed]SubName: Full=Cdc42 effector protein 3 {ECO:0000313|Ensembl:ENSP00000409147}; Flags: Fragment;"]
[10603,"'SH2B2'",83,81,82,"04910///Insulin signaling pathway+++04722///Neurotrophin signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005884///actin filament+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0001725///stress fiber+++GO:0001726///ruffle+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0035591///signaling adaptor activity+++GO:0008236///serine-type peptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0008269///JAK pathway signal transduction adaptor activity+++GO:0005070///SH3/SH2 adaptor activity+++GO:0016787///hydrolase activity+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity+++GO:0004252///serine-type endopeptidase activity","GO:0009967///positive regulation of signal transduction+++GO:0007165///signal transduction+++GO:0001922///B-1 B cell homeostasis+++GO:0006508///proteolysis+++GO:0007399///nervous system development+++GO:0046578///regulation of Ras protein signal transduction+++GO:0007596///blood coagulation+++GO:0050776///regulation of immune response+++GO:0008286///insulin receptor signaling pathway+++GO:0046425///regulation of JAK-STAT cascade+++GO:0050873///brown fat cell differentiation+++GO:0035556///intracellular signal transduction+++GO:0019221///cytokine-mediated signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0050851///antigen receptor-mediated signaling pathway+++GO:0019222///regulation of metabolic process","IPR036290///Phenylalanine zipper superfamily+++IPR001849///Pleckstrin homology domain+++IPR000980///SH2 domain+++IPR011993///PH-like domain superfamily+++IPR030520///SH2B adapter protein 2+++IPR035058///SH2B2, SH2 domain+++IPR036860///SH2 domain superfamily+++IPR015012///Phenylalanine zipper+++IPR030523///SH2B adapter protein","[SH2B2_HUMAN|Reviewed]RecName: Full=SH2B adapter protein 2; AltName: Full=Adapter protein with pleckstrin homology and Src homology 2 domains; AltName: Full=SH2 and PH domain-containing adapter protein APS;+++[A0A087X016_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000483034};+++[C9JK89_HUMAN|Unreviewed]SubName: Full=SH2B adapter protein 2 {ECO:0000313|Ensembl:ENSP00000401883}; Flags: Fragment;+++[Q15098_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59997.1}; Flags: Fragment;+++[Q6LDS3_HUMAN|Unreviewed]SubName: Full=APS protein {ECO:0000313|EMBL:AAA59995.1}; Flags: Fragment;"]
[10605,"'PAIP1'",839,643,741,"03013///RNA transport",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0008494///translation activator activity+++GO:0003723///RNA binding","GO:0048255///mRNA stabilization+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0045727///positive regulation of translation+++GO:0006417///regulation of translation","IPR016024///Armadillo-type fold+++IPR009818///Ataxin-2, C-terminal+++IPR016021///MIF4G-like domain superfamily+++IPR003890///MIF4G-like, type 3","[PAIP1_HUMAN|Reviewed]RecName: Full=Polyadenylate-binding protein-interacting protein 1; Short=PABP-interacting protein 1; Short=PAIP-1; Short=Poly(A)-binding protein-interacting protein 1;+++[A0A024R094_HUMAN|Unreviewed]SubName: Full=Poly(A) binding protein interacting protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW56068.1};+++[A0A1D5RMS4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000427410}; Flags: Fragment;+++[D6R9H8_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000422084};+++[D6RD97_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425406}; Flags: Fragment;+++[D6REB4_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425084};+++[D6RJ02_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425736}; Flags: Fragment;+++[D6RJF2_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000425675}; Flags: Fragment;+++[H0YA44_HUMAN|Unreviewed]SubName: Full=Polyadenylate-binding protein-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000426089}; Flags: Fragment;"]
[10606,"'PAICS'",612,605,608.5,"01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites",null,"M00048///Inosine monophosphate biosynthesis, PRPP + glutamine => IMP","R04209///1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase   1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate <=> Aminoimidazole ribotide + CO2+++R04591///1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)   ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole","GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0045296///cadherin binding+++GO:0043727///5-amino-4-imidazole carboxylate lyase activity+++GO:0003824///catalytic activity+++GO:0004638///phosphoribosylaminoimidazole carboxylase activity+++GO:0016831///carboxy-lyase activity+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0004639///phosphoribosylaminoimidazolesuccinocarboxamide synthase activity+++GO:0000166///nucleotide binding+++GO:0016829///lyase activity+++GO:0016874///ligase activity+++GO:0005515///protein binding","GO:0009113///purine nucleobase biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0008152///metabolic process+++GO:0006189///'de novo' IMP biosynthetic process","IPR018236///SAICAR synthetase, conserved site+++IPR028923///SAICAR synthetase/ADE2, N-terminal+++IPR033626///Class II PurE+++IPR035893///PurE domain superfamily+++IPR000031///PurE domain","[PUR6_HUMAN|Reviewed]RecName: Full=Multifunctional protein ADE2; Includes: RecName: Full=Phosphoribosylaminoimidazole-succinocarboxamide synthase; EC=6.3.2.6; AltName: Full=SAICAR synthetase; Includes: RecName: Full=Phosphoribosylaminoimidazole carboxylase; EC=4.1.1.21; AltName: Full=AIR carboxylase; Short=AIRC;+++[A0A024RD93_HUMAN|Unreviewed]SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_c {ECO:0000313|EMBL:EAX05492.1};+++[D6RF62_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424907}; SubName: Full=Phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, isoform CRA_b {ECO:0000313|EMBL:EAX05490.1};+++[E9PBS1_HUMAN|Unreviewed]SubName: Full=Multifunctional protein ADE2 {ECO:0000313|Ensembl:ENSP00000424053}; Flags: Fragment;"]
[10607,"'TBL3'",755,633,694,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0032040///small-subunit processome+++GO:0005730///nucleolus+++GO:0034388///Pwp2p-containing subcomplex of 90S preribosome+++GO:0005634///nucleus","GO:0030515///snoRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","IPR013934///Small-subunit processome, Utp13+++IPR001680///WD40 repeat+++IPR020472///G-protein beta WD-40 repeat+++IPR036322///WD40-repeat-containing domain superfamily+++IPR019775///WD40 repeat, conserved site+++IPR011044///Quinoprotein amine dehydrogenase, beta chain-like+++IPR017986///WD40-repeat-containing domain+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[TBL3_HUMAN|Reviewed]RecName: Full=Transducin beta-like protein 3; AltName: Full=WD repeat-containing protein SAZD;+++[A0A087WYP7_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000481995};+++[A0JLS5_HUMAN|Unreviewed]SubName: Full=TBL3 protein {ECO:0000313|EMBL:AAH07620.1}; Flags: Fragment;+++[H3BN88_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000454735};+++[J3KNP2_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 3 {ECO:0000313|Ensembl:ENSP00000331815}; Flags: Fragment;"]
[10608,"'MXD4'",3756,3968,3862,{"$nulls":4},"GO:0005634///nucleus","GO:0003714///transcription corepressor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008285///negative regulation of cell proliferation+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain","[MAD4_HUMAN|Reviewed]RecName: Full=Max dimerization protein 4; Short=Max dimerizer 4; AltName: Full=Class C basic helix-loop-helix protein 12; Short=bHLHc12; AltName: Full=Max-associated protein 4; AltName: Full=Max-interacting transcriptional repressor MAD4;+++[D3DVQ5_HUMAN|Unreviewed]SubName: Full=MAX dimerization protein 4, isoform CRA_e {ECO:0000313|EMBL:EAW82535.1};+++[D6RGV1_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000421209};+++[H0Y8Z5_HUMAN|Unreviewed]SubName: Full=Max dimerization protein 4 {ECO:0000313|Ensembl:ENSP00000422660}; Flags: Fragment;+++[Q7Z2R2_HUMAN|Unreviewed]SubName: Full=MSTP149 {ECO:0000313|EMBL:AAQ13695.1};"]
[10609,"'P3H4'",2615.45,2587.08,2601.265,{"$nulls":4},"GO:1902494///catalytic complex+++GO:0000794///condensed nuclear chromosome+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum+++GO:0000795///synaptonemal complex",null,"GO:0032964///collagen biosynthetic process+++GO:0030199///collagen fibril organization+++GO:0046849///bone remodeling+++GO:0017185///peptidyl-lysine hydroxylation+++GO:0007130///synaptonemal complex assembly","IPR033213///Endoplasmic reticulum protein SC65+++IPR011990///Tetratricopeptide-like helical domain superfamily","[SC65_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum protein SC65 {ECO:0000303|PubMed:23959653}; AltName: Full=Leprecan-like protein 4; AltName: Full=Nucleolar autoantigen No55 {ECO:0000303|PubMed:10952778, ECO:0000303|PubMed:8862517}; AltName: Full=Prolyl 3-hydroxylase family member 4 {ECO:0000312|HGNC:HGNC:16946}; AltName: Full=Synaptonemal complex protein SC65 {ECO:0000250|UniProtKB:Q64375}; Flags: Precursor;+++[H0YED7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000435615}; Flags: Fragment;+++[K7EJ03_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000464968}; Flags: Fragment;+++[K7ERA3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum protein SC65 {ECO:0000313|Ensembl:ENSP00000468174}; Flags: Fragment;"]
[10610,"'ST6GALNAC2'",36,39,37.5,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008373///sialyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0001665///alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity+++GO:0016740///transferase activity","GO:0006486///protein glycosylation+++GO:0016266///O-glycan processing+++GO:0006493///protein O-linked glycosylation+++GO:0097503///sialylation+++GO:1990743///protein sialylation","IPR038578///GT29-like superfamiliy+++IPR012163///Sialyltransferase+++IPR001675///Glycosyl transferase family 29","[SIA7B_HUMAN|Reviewed]RecName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2; EC=2.4.99.3 {ECO:0000269|PubMed:10742600, ECO:0000269|PubMed:29251719}; AltName: Full=GalNAc alpha-2,6-sialyltransferase II; AltName: Full=ST6GalNAc II {ECO:0000303|PubMed:10742600}; Short=ST6GalNAcII {ECO:0000303|PubMed:29251719}; AltName: Full=SThM; AltName: Full=Sialyltransferase 7B; Short=SIAT7-B;+++[A0A024R8M1_HUMAN|Unreviewed]SubName: Full=ST6 (Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, isoform CRA_b {ECO:0000313|EMBL:EAW89418.1};+++[K7EIW2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000464915}; Flags: Fragment;+++[K7EKT8_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000465778};+++[K7EMI2_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466513};+++[K7EMM1_HUMAN|Unreviewed]SubName: Full=Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 {ECO:0000313|Ensembl:ENSP00000466560}; Flags: Fragment;"]
[10611,"'PDLIM5'",3857,5712.9,4784.95,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0015629///actin cytoskeleton+++GO:0005913///cell-cell adherens junction+++GO:0045202///synapse+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0042805///actinin binding+++GO:0046872///metal ion binding+++GO:0047485///protein N-terminus binding+++GO:0003779///actin binding+++GO:0005080///protein kinase C binding+++GO:0005515///protein binding+++GO:0098641///cadherin binding involved in cell-cell adhesion","GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0098609///cell-cell adhesion+++GO:0051963///regulation of synapse assembly+++GO:0061001///regulation of dendritic spine morphogenesis","IPR001781///Zinc finger, LIM-type+++IPR001478///PDZ domain+++IPR036034///PDZ superfamily+++IPR031847///Domain of unknown function DUF4749","[PDLI5_HUMAN|Reviewed]RecName: Full=PDZ and LIM domain protein 5; AltName: Full=Enigma homolog; AltName: Full=Enigma-like PDZ and LIM domains protein;+++[A0A024RDE8_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain 5, isoform CRA_c {ECO:0000313|EMBL:EAX06057.1};+++[A0A0A0MSP3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000398469};+++[A0A0D9SFR4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486834}; Flags: Fragment;+++[A0A0D9SFW3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000486938};+++[B7Z481_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54018, highly similar to PDZ and LIM domain protein 5 {ECO:0000313|EMBL:BAH12467.1};+++[B7Z8X5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61541, highly similar to Homo sapiens PDZ and LIM domain 5 (PDLIM5), transcript variant 2, mRNA {ECO:0000313|EMBL:BAH14111.1};+++[D6RAA1_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000423009};+++[D6RGG6_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000426379};+++[H0Y8Y3_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422528}; Flags: Fragment;+++[H0Y929_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000422833}; Flags: Fragment;+++[H0YBI4_HUMAN|Unreviewed]SubName: Full=PDZ and LIM domain protein 5 {ECO:0000313|Ensembl:ENSP00000429577}; Flags: Fragment;+++[Q4W5K9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LIM {ECO:0000313|EMBL:AAY40898.1}; Flags: Fragment;"]
[10612,"'TRIM3'",264,270,267,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005769///early endosome+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0030425///dendrite","GO:0046872///metal ion binding+++GO:0008022///protein C-terminus binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination","IPR001298///Filamin/ABP280 repeat+++IPR003649///B-box, C-terminal+++IPR027370///RING-type zinc-finger, LisH dimerisation motif+++IPR013017///NHL repeat, subgroup+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001258///NHL repeat+++IPR013783///Immunoglobulin-like fold+++IPR011042///Six-bladed beta-propeller, TolB-like+++IPR014756///Immunoglobulin E-set+++IPR001841///Zinc finger, RING-type+++IPR017868///Filamin/ABP280 repeat-like+++IPR017907///Zinc finger, RING-type, conserved site+++IPR000315///B-box-type zinc finger","[TRIM3_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 3; AltName: Full=Brain-expressed RING finger protein; AltName: Full=RING finger protein 22; AltName: Full=RING finger protein 97;+++[A0A1W2PPI7_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000491359};+++[B7Z5Y8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56028, highly similar to Tripartite motif-containing protein 3 {ECO:0000313|EMBL:BAH13074.1};+++[D3DQT3_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_d {ECO:0000313|EMBL:EAW68713.1}; Flags: Fragment;+++[D3DQT4_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 3, isoform CRA_f {ECO:0000313|EMBL:EAW68716.1}; Flags: Fragment;+++[E9PMK8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000433070}; Flags: Fragment;+++[E9PMW5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 3 {ECO:0000313|Ensembl:ENSP00000437283}; Flags: Fragment;+++[L8EAL7_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM3 {ECO:0000313|EMBL:CCQ43796.1};"]
[10613,"'ERLIN1'",385,443,414,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0015485///cholesterol binding","GO:0045541///negative regulation of cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0008202///steroid metabolic process+++GO:0045717///negative regulation of fatty acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0032933///SREBP signaling pathway+++GO:0055085///transmembrane transport","IPR001107///Band 7 domain+++IPR036013///Band 7/SPFH domain superfamily+++IPR033294///Erlin1/2","[ERLN1_HUMAN|Reviewed]RecName: Full=Erlin-1; AltName: Full=Endoplasmic reticulum lipid raft-associated protein 1; AltName: Full=Protein KE04; AltName: Full=Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1; Short=SPFH domain-containing protein 1;+++[B0QZ43_HUMAN|Unreviewed]SubName: Full=Erlin-1 {ECO:0000313|Ensembl:ENSP00000359436}; Flags: Fragment;+++[D3DR65_HUMAN|Unreviewed]SubName: Full=SPFH domain family, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW49847.1};"]
[10614,"'HEXIM1'",743,619,681,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0005515///protein binding+++GO:0097322///7SK snRNA binding+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0017069///snRNA binding","GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0007165///signal transduction+++GO:0045087///innate immune response+++GO:0007507///heart development+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0002376///immune system process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0002218///activation of innate immune response","IPR024872///HEXIM","[HEXI1_HUMAN|Reviewed]RecName: Full=Protein HEXIM1; AltName: Full=Cardiac lineage protein 1; AltName: Full=Estrogen down-regulated gene 1 protein; AltName: Full=Hexamethylene bis-acetamide-inducible protein 1; AltName: Full=Menage a quatre protein 1;+++[Q7L853_HUMAN|Unreviewed]SubName: Full=EDG1 {ECO:0000313|EMBL:AAK01993.1}; Flags: Fragment;"]
[10615,"'SPAG5'",18,29,23.5,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0034451///centriolar satellite+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton+++GO:0005694///chromosome+++GO:0072686///mitotic spindle+++GO:0097431///mitotic spindle pole+++GO:0005874///microtubule+++GO:0030496///midbody+++GO:0000777///condensed chromosome kinetochore+++GO:0005819///spindle+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding+++GO:0008017///microtubule binding","GO:0007059///chromosome segregation+++GO:0032388///positive regulation of intracellular transport+++GO:0007049///cell cycle+++GO:0000070///mitotic sister chromatid segregation+++GO:0090235///regulation of metaphase plate congression+++GO:0051301///cell division+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0007051///spindle organization+++GO:1905832///positive regulation of spindle assembly+++GO:0071539///protein localization to centrosome","IPR028728///Sperm-associated antigen 5","[SPAG5_HUMAN|Reviewed]RecName: Full=Sperm-associated antigen 5; AltName: Full=Astrin; AltName: Full=Deepest; AltName: Full=Mitotic spindle-associated protein p126; Short=MAP126;+++[A4FUA2_HUMAN|Unreviewed]SubName: Full=SPAG5 protein {ECO:0000313|EMBL:AAI13056.1}; Flags: Fragment;+++[F5GZT2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000444223}; Flags: Fragment;+++[J3KSV2_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000462663};+++[J3KTQ0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000463095}; Flags: Fragment;+++[J3QRL6_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464280}; Flags: Fragment;+++[J3QRV8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464400};+++[J3QS12_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000464474}; Flags: Fragment;+++[K7ELC8_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466021}; Flags: Fragment;+++[K7ELG0_HUMAN|Unreviewed]SubName: Full=Sperm-associated antigen 5 {ECO:0000313|Ensembl:ENSP00000466061}; Flags: Fragment;"]
[10616,"'RBCK1'",3654,3738,3696,"04217///Necroptosis+++04621///NOD-like receptor signaling pathway","H01744///Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis",null,null,"GO:0005829///cytosol+++GO:0071797///LUBAC complex","GO:0043130///ubiquitin binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0042802///identical protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0060546///negative regulation of necroptotic process+++GO:0000209///protein polyubiquitination+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0043065///positive regulation of apoptotic process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0097039///protein linear polyubiquitination+++GO:0050852///T cell receptor signaling pathway+++GO:0016032///viral process+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling","IPR002867///IBR domain+++IPR026261///RanBP-type and C3HC4-type zinc finger-containing protein 1+++IPR027370///RING-type zinc-finger, LisH dimerisation motif+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR036443///Zinc finger, RanBP2-type superfamily+++IPR017907///Zinc finger, RING-type, conserved site+++IPR000626///Ubiquitin domain+++IPR029071///Ubiquitin-like domain superfamily+++IPR001876///Zinc finger, RanBP2-type","[HOIL1_HUMAN|Reviewed]RecName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1; EC=2.3.2.31 {ECO:0000269|PubMed:12629548}; AltName: Full=HBV-associated factor 4; AltName: Full=Heme-oxidized IRP2 ubiquitin ligase 1; Short=HOIL-1; AltName: Full=Hepatitis B virus X-associated protein 4; AltName: Full=RING finger protein 54; AltName: Full=RING-type E3 ubiquitin transferase HOIL-1 {ECO:0000305}; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 3;+++[A6PVJ5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000383106};+++[A6PVJ6_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000417173};+++[A6PVJ7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387799}; Flags: Fragment;+++[A6PVK0_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_b {ECO:0000313|EMBL:EAX10674.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371616};+++[B4DML5_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405288}; SubName: Full=cDNA FLJ60704, highly similar to RanBP-type and C3HC4-type zincfinger-containing protein 1 {ECO:0000313|EMBL:BAG59927.1};+++[G3XAG9_HUMAN|Unreviewed]SubName: Full=HCG2019817, isoform CRA_d {ECO:0000313|EMBL:EAX10676.1}; SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000371649};+++[H0Y4S7_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000393841}; Flags: Fragment;+++[Q5JWR1_HUMAN|Unreviewed]SubName: Full=RanBP-type and C3HC4-type zinc finger-containing protein 1 {ECO:0000313|Ensembl:ENSP00000415080}; Flags: Fragment;"]
[10617,"'STAMBP'",889,808,848.5,"04144///Endocytosis","H01872///Microcephaly-capillary malformation syndrome",null,null,"GO:0005634///nucleus+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0070062///extracellular exosome+++GO:0032154///cleavage furrow+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008237///metallopeptidase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0019904///protein domain specific binding","GO:0046580///negative regulation of Ras protein signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0000281///mitotic cytokinesis+++GO:0007259///JAK-STAT cascade+++GO:0070536///protein K63-linked deubiquitination+++GO:0016579///protein deubiquitination+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0006508///proteolysis","IPR037518///MPN domain+++IPR000555///JAB1/MPN/MOV34 metalloenzyme domain+++IPR015063///USP8 dimerisation domain","[STABP_HUMAN|Reviewed]RecName: Full=STAM-binding protein; EC=3.4.19.-; AltName: Full=Associated molecule with the SH3 domain of STAM; AltName: Full=Endosome-associated ubiquitin isopeptidase;+++[A0A140VK54_HUMAN|Unreviewed]SubName: Full=Testicular secretory protein Li 54 {ECO:0000313|EMBL:AEE61191.1};+++[C9JEK5_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000390921}; Flags: Fragment;+++[C9JK83_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413874}; Flags: Fragment;+++[C9JZ93_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000413291}; Flags: Fragment;+++[F5H5B9_HUMAN|Unreviewed]SubName: Full=STAM-binding protein {ECO:0000313|Ensembl:ENSP00000443502};+++[L8ECD1_HUMAN|Unreviewed]SubName: Full=Alternative protein STAMBP {ECO:0000313|EMBL:CCQ43357.1};"]
[10618,"'TGOLN2'",4333.03,5572.73,4952.88,"04137///Mitophagy - animal+++00830///Retinol metabolism+++04140///Autophagy - animal",null,null,"R07163///all-trans-13,14-dihydroretinol:acceptor 13,14-oxidoreductas all-trans-13,14-Dihydroretinol + Acceptor <=> Retinol + Reduced acceptor","GO:0030140///trans-Golgi network transport vesicle+++GO:0005788///endoplasmic reticulum lumen+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0030133///transport vesicle+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0061024///membrane organization+++GO:0044267///cellular protein metabolic process","IPR026084///Trans-Golgi network integral membrane protein TGN38","[TGON2_HUMAN|Reviewed]RecName: Full=Trans-Golgi network integral membrane protein 2; AltName: Full=TGN38 homolog; AltName: Full=TGN46; AltName: Full=TGN48; AltName: Full=Trans-Golgi network protein TGN51; Flags: Precursor;"]
[1062,"'CENPE'",3,2,2.5,null,"H00269///Primary microcephaly (MCPH)",null,null,"GO:0030496///midbody+++GO:0051233///spindle midzone+++GO:0005828///kinetochore microtubule+++GO:0005654///nucleoplasm+++GO:0015630///microtubule cytoskeleton+++GO:0000775///chromosome, centromeric region+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:1990023///mitotic spindle midzone+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0000779///condensed chromosome, centromeric region+++GO:0005874///microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005819///spindle+++GO:0005694///chromosome","GO:0005515///protein binding+++GO:0043515///kinetochore binding+++GO:0016887///ATPase activity+++GO:0003774///motor activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0008017///microtubule binding+++GO:0003777///microtubule motor activity","GO:0007052///mitotic spindle organization+++GO:0051310///metaphase plate congression+++GO:0045860///positive regulation of protein kinase activity+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0007275///multicellular organism development+++GO:0099606///microtubule plus-end directed mitotic chromosome migration+++GO:0099607///lateral attachment of mitotic spindle microtubules to kinetochore+++GO:0051301///cell division+++GO:0007059///chromosome segregation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0007049///cell cycle+++GO:0051382///kinetochore assembly+++GO:0007018///microtubule-based movement+++GO:0000278///mitotic cell cycle+++GO:0007080///mitotic metaphase plate congression+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0051315///attachment of mitotic spindle microtubules to kinetochore","IPR019821///Kinesin motor domain, conserved site+++IPR027640///Kinesin-like protein+++IPR036961///Kinesin motor domain superfamily+++IPR001752///Kinesin motor domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[CENPE_HUMAN|Reviewed]RecName: Full=Centromere-associated protein E; AltName: Full=Centromere protein E; Short=CENP-E; AltName: Full=Kinesin-7 {ECO:0000303|PubMed:25908662}; AltName: Full=Kinesin-related protein CENPE; Flags: Precursor;+++[A0A087X0P0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000483542};+++[D6RBW0_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000423981}; Flags: Fragment;+++[D6RHK2_HUMAN|Unreviewed]SubName: Full=Centromere-associated protein E {ECO:0000313|Ensembl:ENSP00000426023}; Flags: Fragment;"]
[10620,"'ARID3B'",59,69,64,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR023334///REKLES domain+++IPR001606///ARID DNA-binding domain+++IPR036431///ARID DNA-binding domain superfamily","[ARI3B_HUMAN|Reviewed]RecName: Full=AT-rich interactive domain-containing protein 3B; Short=ARID domain-containing protein 3B; AltName: Full=Bright and dead ringer protein; AltName: Full=Bright-like protein;+++[H3BQ92_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 3B {ECO:0000313|Ensembl:ENSP00000455668}; Flags: Fragment;"]
[10621,"'POLR3F'",71,85,78,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding","GO:0002376///immune system process+++GO:0045089///positive regulation of innate immune response+++GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR016049///RNA polymerase Rpc34-like+++IPR007832///RNA polymerase Rpc34","[RPC6_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6; Short=RNA polymerase III subunit C6; AltName: Full=DNA-directed RNA polymerase III subunit F; AltName: Full=RNA polymerase III 39 kDa subunit; Short=RPC39;+++[L8EAI3_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3F {ECO:0000313|EMBL:CCQ43358.1};+++[Q05DB8_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC6 {ECO:0000256|PIRNR:PIRNR028763}; Short=RNA polymerase III subunit C6 {ECO:0000256|PIRNR:PIRNR028763};"]
[10622,"'POLR3G'",13,23,18,"01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++03020///RNA polymerase+++00240///Pyrimidine metabolism+++05169///Epstein-Barr virus infection+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA","GO:0005634///nucleus+++GO:0005666///RNA polymerase III complex+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0002376///immune system process+++GO:0051607///defense response to virus+++GO:0045087///innate immune response+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0045089///positive regulation of innate immune response+++GO:0008283///cell proliferation","IPR024661///DNA-directed RNA polymerase III, subunit Rpc31","[RPC7_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC7; Short=RNA polymerase III subunit C7; AltName: Full=DNA-directed RNA polymerase III subunit G; AltName: Full=RNA polymerase III 32 kDa apha subunit; Short=RPC32-alpha {ECO:0000303|PubMed:20154270}; AltName: Full=RNA polymerase III 32 kDa subunit; Short=RPC32;+++[A0A024RAM1_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase III subunit {ECO:0000256|PIRNR:PIRNR000777};+++[D6R921_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422164}; Flags: Fragment;+++[D6R9U7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000422892}; Flags: Fragment;+++[D6REQ0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000424970}; Flags: Fragment;+++[D6RIT0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000427412}; Flags: Fragment;+++[D6RJH6_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC7 {ECO:0000313|Ensembl:ENSP00000425617};+++[L8E8B4_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3G {ECO:0000313|EMBL:CCQ43359.1};"]
[10623,"'POLR3C'",394,350,372,"05169///Epstein-Barr virus infection+++01100///Metabolic pathways+++00240///Pyrimidine metabolism+++03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex","GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001056///RNA polymerase III activity+++GO:0003697///single-stranded DNA binding","GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0045089///positive regulation of innate immune response+++GO:0006351///transcription, DNA-templated+++GO:0051607///defense response to virus+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0002376///immune system process+++GO:0006383///transcription by RNA polymerase III","IPR039748///DNA-directed RNA polymerase III subunit RPC3+++IPR013197///RNA polymerase III subunit RPC82-related, helix-turn-helix+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR008806///RNA polymerase III Rpc82, C -terminal","[RPC3_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC3; Short=RNA polymerase III subunit C3; AltName: Full=DNA-directed RNA polymerase III subunit C; AltName: Full=RNA polymerase III 62 kDa subunit; Short=RPC62;+++[A0A024R4C1_HUMAN|Unreviewed]SubName: Full=Polymerase (RNA) III (DNA directed) polypeptide C (62kD), isoform CRA_b {ECO:0000313|EMBL:EAW71436.1};+++[E9PHH9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000313|Ensembl:ENSP00000358300};+++[Q9BT08_HUMAN|Unreviewed]SubName: Full=POLR3C protein {ECO:0000313|EMBL:AAH04424.1};"]
[10625,"'IVNS1ABP'",4508,5609,5058.5,"05164///Influenza A",{"$nulls":3},"GO:0043025///neuronal cell body+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005681///spliceosomal complex+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005743///mitochondrial inner membrane+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0016491///oxidoreductase activity","GO:0042493///response to drug+++GO:2001243///negative regulation of intrinsic apoptotic signaling pathway+++GO:0009615///response to virus+++GO:0006383///transcription by RNA polymerase III+++GO:0008380///RNA splicing+++GO:0055114///oxidation-reduction process+++GO:0031397///negative regulation of protein ubiquitination+++GO:0033194///response to hydroperoxide+++GO:0014070///response to organic cyclic compound+++GO:0016032///viral process","IPR006652///Kelch repeat type 1+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR000210///BTB/POZ domain+++IPR017096///BTB-kelch protein+++IPR015915///Kelch-type beta propeller+++IPR029849///Influenza virus NS1A-binding protein+++IPR011043///Galactose oxidase/kelch, beta-propeller+++IPR011705///BTB/Kelch-associated",{"$cut":{"chars":32759,"head":"[NS1BP_HUMAN|Reviewed]RecName: Full=Influenza virus NS1A-binding protein; Short=NS1-BP; Short=NS1-binding protein {ECO:0000303|PubMed:9696811}; AltName: Full=Aryl hydrocarbon receptor-associated protein 3 {ECO:0000303|PubMed:16582008}; AltName: Full=Kelch-like protein 39 {ECO:0000303|PubMed:25619834};+++[A0A023I7N5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q5S8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q700_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q7R1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023Q875_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QC18_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QFT1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QG73_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QHN5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKB4_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QKQ2_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QL98_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QMR7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QR60_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QRY9_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QST8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QUI7_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QW57_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QWQ3_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXG8_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXJ5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QXT5_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QYN1_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0000256|RuleBase:RU000473}; EC=1.6.5.3 {ECO:0000256|RuleBase:RU000473};+++[A0A023QZ36_HUMAN|Unreviewed]RecName: Full=NADH-ubiquinone oxidoreductase chain 1 {ECO:0"}}]
[10626,"'TRIM16'",604.21,508.87,556.54,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016605///PML body","GO:0003676///nucleic acid binding+++GO:0032089///NACHT domain binding+++GO:0016740///transferase activity+++GO:0019966///interleukin-1 binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway+++GO:0043967///histone H4 acetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032526///response to retinoic acid+++GO:0060416///response to growth hormone+++GO:0043966///histone H3 acetylation+++GO:0046683///response to organophosphorus+++GO:0045618///positive regulation of keratinocyte differentiation","IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR003877///SPRY domain+++IPR003879///Butyrophylin-like, SPRY domain+++IPR000315///B-box-type zinc finger+++IPR001870///B30.2/SPRY domain+++IPR006574///SPRY-associated","[TRI16_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 16; AltName: Full=Estrogen-responsive B box protein;+++[B3KP96_HUMAN|Unreviewed]SubName: Full=cDNA FLJ31464 fis, clone NT2NE2001337, highly similar to Tripartite motif-containing protein 16 {ECO:0000313|EMBL:BAG51608.1};+++[J3QKY5_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463293}; Flags: Fragment;+++[J3QL38_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463360}; Flags: Fragment;+++[J3QLP0_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000463639};+++[J3QR69_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000464072}; Flags: Fragment;+++[K7EJH2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465169}; Flags: Fragment;+++[K7EL43_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000465907}; Flags: Fragment;+++[K7ENN8_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 16 {ECO:0000313|Ensembl:ENSP00000467031}; Flags: Fragment;"]
[10627,"'MYL12A'",7819,6361,7090,"04670///Leukocyte transendothelial migration+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++04530///Tight junction+++04611///Platelet activation",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0016459///myosin complex","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006936///muscle contraction+++GO:0070527///platelet aggregation","IPR018247///EF-Hand 1, calcium-binding site+++IPR002048///EF-hand domain+++IPR015070///DJBP, EF-hand domain+++IPR011992///EF-hand domain pair","[ML12A_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12A; AltName: Full=Epididymis secretory protein Li 24; Short=HEL-S-24; AltName: Full=MLC-2B; AltName: Full=Myosin RLC; AltName: Full=Myosin regulatory light chain 2, nonsarcomeric; AltName: Full=Myosin regulatory light chain MRLC3;+++[ML12B_HUMAN|Reviewed]RecName: Full=Myosin regulatory light chain 12B; AltName: Full=MLC-2A; Short=MLC-2; AltName: Full=Myosin regulatory light chain 2-B, smooth muscle isoform; AltName: Full=Myosin regulatory light chain 20 kDa; Short=MLC20; AltName: Full=Myosin regulatory light chain MRLC2; AltName: Full=SHUJUN-1;+++[J3KT92_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000462865}; Flags: Fragment;+++[J3KTJ1_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000463009}; Flags: Fragment;+++[J3QRS3_HUMAN|Unreviewed]SubName: Full=Myosin regulatory light chain 12A {ECO:0000313|Ensembl:ENSP00000464359}; SubName: Full=Myosin regulatory light chain MRCL3, isoform CRA_b {ECO:0000313|EMBL:EAX01679.1};"]
[10628,"'TXNIP'",1018,1067,1042.5,"04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005758///mitochondrial intermembrane space+++GO:0005737///cytoplasm","GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0051782///negative regulation of cell division+++GO:0042127///regulation of cell proliferation+++GO:0009749///response to glucose+++GO:0030216///keratinocyte differentiation+++GO:0006979///response to oxidative stress+++GO:0042493///response to drug+++GO:0007049///cell cycle+++GO:0043086///negative regulation of catalytic activity+++GO:0006606///protein import into nucleus+++GO:0051592///response to calcium ion+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032355///response to estradiol+++GO:0032570///response to progesterone+++GO:0009612///response to mechanical stimulus+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0042542///response to hydrogen peroxide+++GO:0071228///cellular response to tumor cell","IPR014752///Arrestin, C-terminal+++IPR011022///Arrestin C-terminal-like domain+++IPR011021///Arrestin-like, N-terminal+++IPR014756///Immunoglobulin E-set","[TXNIP_HUMAN|Reviewed]RecName: Full=Thioredoxin-interacting protein; AltName: Full=Thioredoxin-binding protein 2; AltName: Full=Vitamin D3 up-regulated protein 1;+++[A0A024R4B7_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAW71411.1};+++[B1ALI9_HUMAN|Unreviewed]SubName: Full=Thioredoxin interacting protein {ECO:0000313|EMBL:CAI22352.1}; Flags: Fragment;+++[L8E7V6_HUMAN|Unreviewed]SubName: Full=Alternative protein TXNIP {ECO:0000313|EMBL:CCQ43360.1};"]
[10629,"'TAF6L'",231,165,198,"05168///Herpes simplex infection+++03022///Basal transcription factors","H01879///Wiedemann-Steiner syndrome",null,null,"GO:0005669///transcription factor TFIID complex+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0046695///SLIK (SAGA-like) complex+++GO:0030914///STAGA complex+++GO:0000124///SAGA complex+++GO:0000118///histone deacetylase complex","GO:0003713///transcription coactivator activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0004402///histone acetyltransferase activity","GO:0043966///histone H3 acetylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006338///chromatin remodeling+++GO:0006366///transcription by RNA polymerase II+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006352///DNA-templated transcription, initiation+++GO:0006325///chromatin organization","IPR011442///TAF6, C-terminal HEAT repeat domain+++IPR009072///Histone-fold+++IPR004823///TATA box binding protein associated factor (TAF)+++IPR037796///Transcription initiation factor TFIID subunit 6","[TAF6L_HUMAN|Reviewed]RecName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; AltName: Full=PCAF-associated factor 65-alpha; Short=PAF65-alpha;+++[A0A024R5A7_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_a {ECO:0000313|EMBL:EAW74094.1};+++[A8K0D4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78693, highly similar to Homo sapiens TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa (TAF6L), mRNA {ECO:0000313|EMBL:BAF82188.1};+++[B4DVM4_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa, isoform CRA_b {ECO:0000313|EMBL:EAW74095.1}; SubName: Full=cDNA FLJ57614, highly similar to TAF6-like RNA polymerase IIp300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|EMBL:BAG62736.1};+++[E9PK90_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435443};+++[E9PLV8_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000435116}; Flags: Fragment;+++[E9PP94_HUMAN|Unreviewed]SubName: Full=TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L {ECO:0000313|Ensembl:ENSP00000434662}; Flags: Fragment;"]
[1063,"'CENPF'",23,24,23.5,null,"H01814///Stromme syndrome",null,null,"GO:0005930///axoneme+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0045120///pronucleus+++GO:0016363///nuclear matrix+++GO:0000776///kinetochore+++GO:0005635///nuclear envelope+++GO:0097539///ciliary transition fiber+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005819///spindle+++GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0030496///midbody+++GO:0005694///chromosome+++GO:0000940///condensed chromosome outer kinetochore+++GO:0000922///spindle pole+++GO:0000777///condensed chromosome kinetochore+++GO:0000775///chromosome, centromeric region","GO:0042803///protein homodimerization activity+++GO:0070840///dynein complex binding+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0003682///chromatin binding+++GO:0008134///transcription factor binding","GO:0021591///ventricular system development+++GO:0001822///kidney development+++GO:0030154///cell differentiation+++GO:0007059///chromosome segregation+++GO:0007517///muscle organ development+++GO:0016202///regulation of striated muscle tissue development+++GO:0051310///metaphase plate congression+++GO:0042493///response to drug+++GO:0000278///mitotic cell cycle+++GO:0051301///cell division+++GO:0015031///protein transport+++GO:0007094///mitotic spindle assembly checkpoint+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0051726///regulation of cell cycle+++GO:0007275///multicellular organism development+++GO:0007049///cell cycle+++GO:0008283///cell proliferation+++GO:0051382///kinetochore assembly+++GO:0071897///DNA biosynthetic process","IPR018463///Centromere protein Cenp-F, N-terminal+++IPR018302///Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain+++IPR019513///Centromere protein Cenp-F, leucine-rich repeat-containing domain","[CENPF_HUMAN|Reviewed]RecName: Full=Centromere protein F; Short=CENP-F; AltName: Full=AH antigen; AltName: Full=Kinetochore protein CENPF; AltName: Full=Mitosin; Flags: Precursor;+++[A0A087WTY4_HUMAN|Unreviewed]SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSP00000478221};"]
[10630,"'PDPN'",2194,1698,1946,{"$nulls":4},"GO:0032587///ruffle membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016323///basolateral plasma membrane+++GO:0071437///invadopodium+++GO:0030054///cell junction+++GO:0030175///filopodium+++GO:0031528///microvillus membrane+++GO:0031258///lamellipodium membrane+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0061851///leading edge of lamellipodium+++GO:0001726///ruffle+++GO:0016324///apical plasma membrane+++GO:0031527///filopodium membrane+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0097197///tetraspanin-enriched microdomain+++GO:0045121///membrane raft+++GO:0005829///cytosol+++GO:0005886///plasma membrane","GO:0019956///chemokine binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding+++GO:0005372///water transmembrane transporter activity+++GO:0015250///water channel activity+++GO:0051087///chaperone binding+++GO:0008517///folic acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity","GO:0044319///wound healing, spreading of cells+++GO:1901731///positive regulation of platelet aggregation+++GO:0001946///lymphangiogenesis+++GO:0060838///lymphatic endothelial cell fate commitment+++GO:0000902///cell morphogenesis+++GO:0003333///amino acid transmembrane transport+++GO:0007266///Rho protein signal transduction+++GO:0007275///multicellular organism development+++GO:0006833///water transport+++GO:0008360///regulation of cell shape+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0090091///positive regulation of extracellular matrix disassembly+++GO:1904328///regulation of myofibroblast contraction+++GO:0008285///negative regulation of cell proliferation+++GO:0051272///positive regulation of cellular component movement+++GO:0015884///folic acid transport+++GO:0030335///positive regulation of cell migration+++GO:0070252///actin-mediated cell contraction+++GO:0030324///lung development+++GO:2000392///regulation of lamellipodium morphogenesis+++GO:0048535///lymph node development+++GO:1900024///regulation of substrate adhesion-dependent cell spreading+++GO:1905863///invadopodium organization+++GO:0006865///amino acid transport+++GO:0043066///negative regulation of apoptotic process+++GO:0030168///platelet activation","IPR008783///Podoplanin","[PDPN_HUMAN|Reviewed]RecName: Full=Podoplanin {ECO:0000303|Ref.9}; AltName: Full=Aggrus {ECO:0000303|Ref.3}; AltName: Full=Glycoprotein 36; Short=Gp36 {ECO:0000303|PubMed:10393083}; AltName: Full=PA2.26 antigen {ECO:0000303|PubMed:15515019}; AltName: Full=T1-alpha {ECO:0000250|UniProtKB:Q64294}; Short=T1A {ECO:0000250|UniProtKB:Q64294}; Contains: RecName: Full=29kDa cytosolic podoplanin intracellular domain {ECO:0000303|PubMed:24275092}; Short=PICD {ECO:0000303|PubMed:24275092}; Flags: Precursor;+++[D6RH07_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426210};+++[E7ETC6_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000422977};+++[H0Y8Q3_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000421742}; Flags: Fragment;+++[H0YA72_HUMAN|Unreviewed]SubName: Full=Podoplanin {ECO:0000313|Ensembl:ENSP00000426302};"]
[10631,"'POSTN'",9890,16117,13003.5,{"$nulls":4},"GO:0005802///trans-Golgi network+++GO:0005576///extracellular region+++GO:0031012///extracellular matrix+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005615///extracellular space+++GO:0031594///neuromuscular junction+++GO:0062023///collagen-containing extracellular matrix","GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0046872///metal ion binding","GO:0071307///cellular response to vitamin K+++GO:0001666///response to hypoxia+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0009888///tissue development+++GO:0001501///skeletal system development+++GO:1904209///positive regulation of chemokine (C-C motif) ligand 2 secretion+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:0014850///response to muscle activity+++GO:1990138///neuron projection extension+++GO:0032355///response to estradiol+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0030198///extracellular matrix organization+++GO:0008593///regulation of Notch signaling pathway+++GO:0042060///wound healing+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0007155///cell adhesion+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:1990523///bone regeneration+++GO:0009612///response to mechanical stimulus+++GO:0003073///regulation of systemic arterial blood pressure","IPR000782///FAS1 domain+++IPR011489///EMI domain+++IPR036378///FAS1 domain superfamily+++IPR016666///TGF beta-induced protein/periostin","[POSTN_HUMAN|Reviewed]RecName: Full=Periostin; Short=PN; AltName: Full=Osteoblast-specific factor 2; Short=OSF-2; Flags: Precursor;+++[A0A024RDS2_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_c {ECO:0000313|EMBL:EAX08594.1};+++[A0A024RDT5_HUMAN|Unreviewed]SubName: Full=Periostin, osteoblast specific factor, isoform CRA_a {ECO:0000313|EMBL:EAX08591.1};+++[B1ALD9_HUMAN|Unreviewed]SubName: Full=Periostin {ECO:0000313|Ensembl:ENSP00000369073};"]
[10632,"'ATP5MG'",994,880,937,"04714///Thermogenesis+++00190///Oxidative phosphorylation+++01100///Metabolic pathways",null,"M00158///F-type ATPase, eukaryotes",null,"GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0000276///mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0045263///proton-transporting ATP synthase complex, coupling factor F(o)+++GO:0005753///mitochondrial proton-transporting ATP synthase complex+++GO:0016020///membrane","GO:0015078///proton transmembrane transporter activity+++GO:0016887///ATPase activity+++GO:0022857///transmembrane transporter activity+++GO:0046933///proton-transporting ATP synthase activity, rotational mechanism","GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006754///ATP biosynthetic process+++GO:0042776///mitochondrial ATP synthesis coupled proton transport+++GO:0042407///cristae formation+++GO:0015986///ATP synthesis coupled proton transport+++GO:0006811///ion transport","IPR016702///Mitochondrial ATP synthase subunit g, animal+++IPR006808///ATP synthase, F0 complex, subunit G, mitochondrial","[ATP5L_HUMAN|Reviewed]RecName: Full=ATP synthase subunit g, mitochondrial {ECO:0000305}; Short=ATPase subunit g; AltName: Full=ATP synthase membrane subunit g {ECO:0000305};+++[E9PN17_HUMAN|Unreviewed]SubName: Full=ATP synthase membrane subunit g {ECO:0000313|Ensembl:ENSP00000434865};"]
[10633,"'RASL10A'",7,4,5.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005886///plasma membrane","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0000166///nucleotide binding","GO:0007165///signal transduction+++GO:0007264///small GTPase mediated signal transduction","IPR020849///Small GTPase superfamily, Ras-type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001806///Small GTPase","[RSLAA_HUMAN|Reviewed]RecName: Full=Ras-like protein family member 10A; AltName: Full=Ras-like protein RRP22; AltName: Full=Ras-related protein on chromosome 22; Flags: Precursor;+++[A0A024R1C8_HUMAN|Unreviewed]SubName: Full=RAS-related on chromosome 22, isoform CRA_a {ECO:0000313|EMBL:EAW59797.1};+++[L8E9A0_HUMAN|Unreviewed]SubName: Full=Alternative protein RASL10A {ECO:0000313|EMBL:CCQ42928.1};"]
[10634,"'GAS2L1'",1150,1094,1122,{"$nulls":4},"GO:0005874///microtubule+++GO:0001725///stress fiber+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0046966///thyroid hormone receptor binding","GO:0001578///microtubule bundle formation+++GO:0097067///cellular response to thyroid hormone stimulus+++GO:0009267///cellular response to starvation+++GO:0007026///negative regulation of microtubule depolymerization+++GO:0010629///negative regulation of gene expression+++GO:0051726///regulation of cell cycle+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0030308///negative regulation of cell growth+++GO:0007050///cell cycle arrest","IPR036534///GAR domain superfamily+++IPR001715///Calponin homology domain+++IPR003108///GAR domain+++IPR036872///CH domain superfamily+++IPR029931///GAS2-like protein 1","[GA2L1_HUMAN|Reviewed]RecName: Full=GAS2-like protein 1; AltName: Full=GAS2-related protein on chromosome 22; AltName: Full=Growth arrest-specific protein 2-like 1;+++[A0A024R1J4_HUMAN|Unreviewed]SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_b {ECO:0000313|EMBL:EAW59794.1};+++[A0A5E8_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000478343}; SubName: Full=Growth arrest-specific 2 like 1, isoform CRA_a {ECO:0000313|EMBL:EAW59788.1}; SubName: Full=cDNA FLJ16435 fis, clone BRACE3020671, highly similar to GAS2-like protein 1 {ECO:0000313|EMBL:BAG53749.1}; SubName: Full=cDNA FLJ36067 fis, clone TESTI2019308, highly similar to GAR22 PROTEIN {ECO:0000313|EMBL:BAC04150.1};+++[C9JFI0_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000395988}; Flags: Fragment;+++[C9JRR6_HUMAN|Unreviewed]SubName: Full=GAS2-like protein 1 {ECO:0000313|Ensembl:ENSP00000388645}; Flags: Fragment;"]
[10635,"'RAD51AP1'",3,12,7.5,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin","GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0003723///RNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0006310///DNA recombination+++GO:0036297///interstrand cross-link repair+++GO:0071479///cellular response to ionizing radiation+++GO:0000724///double-strand break repair via homologous recombination+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006281///DNA repair","IPR031419///RAD51 interacting motif+++IPR026632///RAD51-associated protein 1","[R51A1_HUMAN|Reviewed]RecName: Full=RAD51-associated protein 1; AltName: Full=RAD51-interacting protein;+++[F5H031_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000438422};+++[F5H1Y0_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000446296};+++[F5H4V6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439925};+++[F5H710_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000442890};+++[H0YFK6_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439019}; Flags: Fragment;+++[H0YGT5_HUMAN|Unreviewed]SubName: Full=RAD51-associated protein 1 {ECO:0000313|Ensembl:ENSP00000444769}; Flags: Fragment;"]
[10636,"'RGS14'",259,188,223.5,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016604///nuclear body+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0043197///dendritic spine+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0000922///spindle pole+++GO:0030425///dendrite+++GO:0005813///centrosome+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0032794///GTPase activating protein binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0008017///microtubule binding+++GO:0019901///protein kinase binding+++GO:0005092///GDP-dissociation inhibitor activity+++GO:0030159///receptor signaling complex scaffold activity+++GO:0030695///GTPase regulator activity+++GO:0005515///protein binding","GO:0060291///long-term synaptic potentiation+++GO:0051301///cell division+++GO:0006913///nucleocytoplasmic transport+++GO:0007049///cell cycle+++GO:0007051///spindle organization+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007616///long-term memory+++GO:0008542///visual learning+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0007612///learning+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0000278///mitotic cell cycle+++GO:0007059///chromosome segregation+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0006979///response to oxidative stress+++GO:0050790///regulation of catalytic activity+++GO:0007165///signal transduction+++GO:0010070///zygote asymmetric cell division+++GO:0031914///negative regulation of synaptic plasticity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0009968///negative regulation of signal transduction+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0050769///positive regulation of neurogenesis+++GO:0035556///intracellular signal transduction+++GO:0043407///negative regulation of MAP kinase activity","IPR036305///RGS domain superfamily+++IPR024066///RGS, subdomain 1/3+++IPR016137///RGS domain+++IPR030776///Regulator of G-protein signalling 14+++IPR003116///Raf-like Ras-binding+++IPR037881///RGS14, RGS domain+++IPR029071///Ubiquitin-like domain superfamily+++IPR003109///GoLoco motif","[RGS14_HUMAN|Reviewed]RecName: Full=Regulator of G-protein signaling 14; Short=RGS14;+++[A0A024R7N4_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein signalling 14, isoform CRA_a {ECO:0000313|EMBL:EAW85013.1};+++[H0Y8W3_HUMAN|Unreviewed]SubName: Full=Regulator of G-protein-signaling 14 {ECO:0000313|Ensembl:ENSP00000422329}; Flags: Fragment;"]
[10637,"'LEFTY1'",1,0,0.5,"04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005160///transforming growth factor beta receptor binding+++GO:0008083///growth factor activity+++GO:0005125///cytokine activity","GO:0060395///SMAD protein signal transduction+++GO:0043408///regulation of MAPK cascade+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042981///regulation of apoptotic process+++GO:0003007///heart morphogenesis+++GO:0010469///regulation of signaling receptor activity+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0048468///cell development+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0007368///determination of left/right symmetry+++GO:0007275///multicellular organism development","IPR029034///Cystine-knot cytokine+++IPR001839///Transforming growth factor-beta, C-terminal+++IPR003942///Left- Right determination factor+++IPR001111///TGF-beta, propeptide+++IPR015615///Transforming growth factor-beta-related+++IPR017948///Transforming growth factor beta, conserved site","[LFTY1_HUMAN|Reviewed]RecName: Full=Left-right determination factor 1; AltName: Full=Left-right determination factor B; AltName: Full=Protein lefty-1; AltName: Full=Protein lefty-B; Flags: Precursor;+++[A0A087WW09_HUMAN|Unreviewed]SubName: Full=Left-right determination factor 1 {ECO:0000313|Ensembl:ENSP00000479837}; Flags: Fragment;"]
[10640,"'EXOC5'",469,585,527,{"$nulls":4},"GO:0005829///cytosol+++GO:0000145///exocyst+++GO:0030496///midbody+++GO:0005737///cytoplasm","GO:0047485///protein N-terminus binding+++GO:0005515///protein binding+++GO:0017160///Ral GTPase binding","GO:0048873///homeostasis of number of cells within a tissue+++GO:1905515///non-motile cilium assembly+++GO:1904019///epithelial cell apoptotic process+++GO:0001736///establishment of planar polarity+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0048278///vesicle docking+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0006887///exocytosis+++GO:0006893///Golgi to plasma membrane transport","IPR033960///Exocyst complex component EXOC5/Sec10+++IPR009976///Exocyst complex component Sec10-like","[EXOC5_HUMAN|Reviewed]RecName: Full=Exocyst complex component 5; AltName: Full=Exocyst complex component Sec10; Short=hSec10;+++[A0A0A0MSI8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000389934};+++[F8W9B8_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000342100};+++[G3V377_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000451082};+++[G3V4Z7_HUMAN|Unreviewed]SubName: Full=Exocyst complex component 5 {ECO:0000313|Ensembl:ENSP00000452084}; Flags: Fragment;"]
[10641,"'NPRL2'",333,262,297.5,"04150///mTOR signaling pathway",{"$nulls":3},"GO:1990130///GATOR1 complex+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0042802///identical protein binding+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0042562///hormone binding+++GO:0005525///GTP binding+++GO:0004713///protein tyrosine kinase activity+++GO:0017046///peptide hormone binding+++GO:0005096///GTPase activator activity+++GO:0000166///nucleotide binding+++GO:0004383///guanylate cyclase activity+++GO:0001653///peptide receptor activity+++GO:0004672///protein kinase activity+++GO:0016829///lyase activity+++GO:0016941///natriuretic peptide receptor activity","GO:2000785///regulation of autophagosome assembly+++GO:0060348///bone development+++GO:0033673///negative regulation of kinase activity+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:1900194///negative regulation of oocyte maturation+++GO:0022414///reproductive process+++GO:0035556///intracellular signal transduction+++GO:0007165///signal transduction+++GO:0008217///regulation of blood pressure+++GO:0007168///receptor guanylyl cyclase signaling pathway+++GO:0097011///cellular response to granulocyte macrophage colony-stimulating factor stimulus+++GO:0032007///negative regulation of TOR signaling+++GO:0043547///positive regulation of GTPase activity+++GO:0006182///cGMP biosynthetic process+++GO:0006468///protein phosphorylation+++GO:0006995///cellular response to nitrogen starvation+++GO:0034198///cellular response to amino acid starvation+++GO:0051447///negative regulation of meiotic cell cycle+++GO:1903779///regulation of cardiac conduction+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0001503///ossification+++GO:0019934///cGMP-mediated signaling+++GO:0010508///positive regulation of autophagy","IPR009348///Nitrogen permease regulator 2","[NPRL2_HUMAN|Reviewed]RecName: Full=GATOR complex protein NPRL2 {ECO:0000305}; AltName: Full=Gene 21 protein {ECO:0000303|Ref.1}; Short=G21 protein {ECO:0000303|Ref.1}; AltName: Full=Nitrogen permease regulator 2-like protein {ECO:0000303|PubMed:11085536}; Short=NPR2-like protein {ECO:0000303|PubMed:11085536}; AltName: Full=Tumor suppressor candidate 4 {ECO:0000303|PubMed:18616680};+++[A6NJF2_HUMAN|Unreviewed]SubName: Full=Natriuretic peptide receptor B/guanylate cyclase B (Atrionatriuretic peptide receptor B) variant 3 {ECO:0000313|EMBL:ACA05922.1};+++[F2Z2R8_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000396172};+++[F2Z3D4_HUMAN|Unreviewed]SubName: Full=GATOR complex protein NPRL2 {ECO:0000313|Ensembl:ENSP00000412779};+++[H7C056_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000393029}; Flags: Fragment;+++[H7C1A1_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000399204}; Flags: Fragment;+++[H7C1X0_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide receptor 2 {ECO:0000313|Ensembl:ENSP00000402902}; Flags: Fragment;"]
[10642,"'IGF2BP1'",905,1208,1056.5,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0043197///dendritic spine+++GO:0030424///axon+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0010494///cytoplasmic stress granule+++GO:0070937///CRD-mediated mRNA stability complex+++GO:0030425///dendrite+++GO:0042995///cell projection+++GO:0030027///lamellipodium+++GO:0030426///growth cone+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003676///nucleic acid binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003723///RNA binding+++GO:0048027///mRNA 5'-UTR binding+++GO:0003692///left-handed Z-DNA binding+++GO:0042802///identical protein binding+++GO:0003726///double-stranded RNA adenosine deaminase activity+++GO:0003729///mRNA binding","GO:0010610///regulation of mRNA stability involved in response to stress+++GO:0097150///neuronal stem cell population maintenance+++GO:0060340///positive regulation of type I interferon-mediated signaling pathway+++GO:0006403///RNA localization+++GO:0002376///immune system process+++GO:0006417///regulation of translation+++GO:0022013///pallium cell proliferation in forebrain+++GO:0017148///negative regulation of translation+++GO:0045087///innate immune response+++GO:0008150///biological_process+++GO:0070934///CRD-mediated mRNA stabilization+++GO:0032479///regulation of type I interferon production+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0043488///regulation of mRNA stability+++GO:0032481///positive regulation of type I interferon production","IPR036612///K Homology domain, type 1 superfamily+++IPR034842///IGF2BP1, RNA recognition motif 2+++IPR035979///RNA-binding domain superfamily+++IPR034837///IGF2BP1, RNA recognition motif 1+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR004087///K Homology domain+++IPR004088///K Homology domain, type 1+++IPR000504///RNA recognition motif domain","[IF2B1_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 1; Short=IGF2 mRNA-binding protein 1; Short=IMP-1; Short=IMP1; AltName: Full=Coding region determinant-binding protein; Short=CRD-BP; AltName: Full=IGF-II mRNA-binding protein 1; AltName: Full=VICKZ family member 1; AltName: Full=Zipcode-binding protein 1; Short=ZBP-1;+++[D3DTW3_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP {ECO:0000313|EMBL:AKM97296.1}; SubName: Full=Insulin-like growth factor 2 mRNA binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94694.1};+++[L8ECD2_HUMAN|Unreviewed]SubName: Full=Alternative protein IGF2BP1 {ECO:0000313|EMBL:CCQ43362.1};"]
[10643,"'IGF2BP3'",1188,1229,1208.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0048027///mRNA 5'-UTR binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity+++GO:0003730///mRNA 3'-UTR binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability+++GO:0051028///mRNA transport+++GO:0017148///negative regulation of translation+++GO:0006412///translation+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0006417///regulation of translation","IPR004088///K Homology domain, type 1+++IPR004087///K Homology domain+++IPR034844///IGF2BP3, RNA recognition motif 2+++IPR036612///K Homology domain, type 1 superfamily+++IPR000504///RNA recognition motif domain+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[IF2B3_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 3; Short=IGF2 mRNA-binding protein 3; Short=IMP-3; AltName: Full=IGF-II mRNA-binding protein 3; AltName: Full=KH domain-containing protein overexpressed in cancer; Short=hKOC; AltName: Full=VICKZ family member 3;+++[F8WD15_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 3 {ECO:0000313|Ensembl:ENSP00000395936};"]
[10644,"'IGF2BP2'",1169,1307,1238,null,"H00409///Type II diabetes mellitus",null,null,"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0003729///mRNA binding+++GO:0003730///mRNA 3'-UTR binding","GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0051028///mRNA transport+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0009653///anatomical structure morphogenesis+++GO:0043488///regulation of mRNA stability","IPR034843///IGF2BP2, RNA recognition motif 1+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR036612///K Homology domain, type 1 superfamily+++IPR000504///RNA recognition motif domain+++IPR004088///K Homology domain, type 1+++IPR004087///K Homology domain+++IPR035979///RNA-binding domain superfamily+++IPR028743///Insulin-like growth factor 2 mRNA-binding protein 2","[IF2B2_HUMAN|Reviewed]RecName: Full=Insulin-like growth factor 2 mRNA-binding protein 2; Short=IGF2 mRNA-binding protein 2; Short=IMP-2; AltName: Full=Hepatocellular carcinoma autoantigen p62; AltName: Full=IGF-II mRNA-binding protein 2; AltName: Full=VICKZ family member 2;+++[B3FTN5_HUMAN|Unreviewed]SubName: Full=Truncated insulin-like 2 growth factor 2-binding protein 2 {ECO:0000313|EMBL:ACB86628.1};+++[B4DKT5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53054, highly similar to Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|EMBL:BAG59297.1};+++[F8W930_HUMAN|Unreviewed]SubName: Full=Insulin-like growth factor 2 mRNA-binding protein 2 {ECO:0000313|Ensembl:ENSP00000410242};"]
[10645,"'CAMKK2'",468,626,547,"04140///Autophagy - animal+++04152///AMPK signaling pathway+++04920///Adipocytokine signaling pathway+++04921///Oxytocin signaling pathway+++04211///Longevity regulating pathway+++05034///Alcoholism",{"$nulls":3},"GO:0005622///intracellular+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0042995///cell projection","GO:0004683///calmodulin-dependent protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005509///calcium ion binding+++GO:0004713///protein tyrosine kinase activity+++GO:0005516///calmodulin binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding","GO:0016310///phosphorylation+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0000165///MAPK cascade+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0046777///protein autophosphorylation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0019722///calcium-mediated signaling+++GO:0061762///CAMKK-AMPK signaling cascade+++GO:0006468///protein phosphorylation+++GO:0034614///cellular response to reactive oxygen species+++GO:0045859///regulation of protein kinase activity+++GO:0018108///peptidyl-tyrosine phosphorylation","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[KKCC2_HUMAN|Reviewed]RecName: Full=Calcium/calmodulin-dependent protein kinase kinase 2; Short=CaM-KK 2; Short=CaM-kinase kinase 2; Short=CaMKK 2; EC=2.7.11.17; AltName: Full=Calcium/calmodulin-dependent protein kinase kinase beta; Short=CaM-KK beta; Short=CaM-kinase kinase beta; Short=CaMKK beta;+++[A0A024RBP6_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_b {ECO:0000313|EMBL:EAW98251.1};+++[A0A024RBP8_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_d {ECO:0000313|EMBL:EAW98256.1};+++[A0A024RBQ0_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_f {ECO:0000313|EMBL:EAW98258.1};+++[A0A024RBQ3_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2, beta, isoform CRA_e {ECO:0000313|EMBL:EAW98257.1};+++[F5GZ00_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000441352};+++[F5H360_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000445400}; Flags: Fragment;+++[F5H4I7_HUMAN|Unreviewed]SubName: Full=Calcium/calmodulin-dependent protein kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000444894}; Flags: Fragment;+++[Q8IZW1_HUMAN|Unreviewed]SubName: Full=CAMKK beta protein {ECO:0000313|EMBL:AAN37388.1}; Flags: Fragment;"]
[10650,"'PRELID3A'",98,80,89,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005758///mitochondrial intermembrane space","GO:0005515///protein binding+++GO:1990050///phosphatidic acid transporter activity","GO:0015914///phospholipid transport+++GO:0006869///lipid transport","IPR037365///Slowmo/Ups family+++IPR006797///PRELI/MSF1 domain","[PLD3A_HUMAN|Reviewed]RecName: Full=PRELI domain containing protein 3A; AltName: Full=Protein slowmo homolog 1;+++[K7ELB4_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000465996}; Flags: Fragment;+++[K7ENN4_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467026};+++[K7EP78_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467261};+++[K7EPM9_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467457}; Flags: Fragment;+++[K7EQM5_HUMAN|Unreviewed]SubName: Full=PRELI domain-containing protein 3A {ECO:0000313|Ensembl:ENSP00000467896}; Flags: Fragment;"]
[10651,"'MTX2'",142,129,135.5,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0001401///mitochondrial sorting and assembly machinery complex+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006839///mitochondrial transport+++GO:0015031///protein transport","IPR036282///Glutathione S-transferase, C-terminal domain superfamily+++IPR040079///Glutathione Transferase family+++IPR033468///Metaxin, glutathione S-transferase domain+++IPR019564///Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain","[MTX2_HUMAN|Reviewed]RecName: Full=Metaxin-2; AltName: Full=Mitochondrial outer membrane import complex protein 2;+++[C9JAZ1_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000398757}; Flags: Fragment;+++[C9JNK6_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000414176};+++[F8WCW1_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000403545};+++[F8WE26_HUMAN|Unreviewed]SubName: Full=Metaxin-2 {ECO:0000313|Ensembl:ENSP00000402204};"]
[10652,"'YKT6'",2896,2559,2727.5,"04138///Autophagy - yeast+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0097440///apical dendrite+++GO:0005783///endoplasmic reticulum+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0031201///SNARE complex+++GO:0005829///cytosol+++GO:0030133///transport vesicle+++GO:0005739///mitochondrion+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0097441///basal dendrite+++GO:0000139///Golgi membrane+++GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane","GO:0005484///SNAP receptor activity+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0061025///membrane fusion+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0015031///protein transport+++GO:0006903///vesicle targeting+++GO:0016192///vesicle-mediated transport+++GO:0006904///vesicle docking involved in exocytosis+++GO:0006888///ER to Golgi vesicle-mediated transport","IPR010908///Longin domain+++IPR001388///Synaptobrevin+++IPR011012///Longin-like domain superfamily","[YKT6_HUMAN|Reviewed]RecName: Full=Synaptobrevin homolog YKT6; EC=2.3.1.- {ECO:0000269|PubMed:15479160}; Flags: Precursor;+++[A4D2J0_HUMAN|Unreviewed]SubName: Full=SNARE protein Ykt6 {ECO:0000313|EMBL:EAL23763.1}; SubName: Full=SNARE protein Ykt6, isoform CRA_a {ECO:0000313|EMBL:EAW61111.1}; SubName: Full=cDNA, FLJ93006, Homo sapiens SNARE protein Ykt6 (YKT6), mRNA {ECO:0000313|EMBL:BAG35508.1};+++[B5BU81_HUMAN|Unreviewed]SubName: Full=YKT6 v-SNARE protein {ECO:0000313|EMBL:BAG70131.1};+++[H7C3K7_HUMAN|Unreviewed]SubName: Full=Synaptobrevin homolog YKT6 {ECO:0000313|Ensembl:ENSP00000412414}; Flags: Fragment;"]
[10653,"'SPINT2'",6297,4840,5568.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane","GO:0004866///endopeptidase inhibitor activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:2000146///negative regulation of cell motility+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010466///negative regulation of peptidase activity+++GO:0060672///epithelial cell morphogenesis involved in placental branching+++GO:2000178///negative regulation of neural precursor cell proliferation+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0071711///basement membrane organization+++GO:0071773///cellular response to BMP stimulus+++GO:0007163///establishment or maintenance of cell polarity+++GO:0001843///neural tube closure","IPR020901///Proteinase inhibitor I2, Kunitz, conserved site+++IPR036880///Pancreatic trypsin inhibitor Kunitz domain superfamily+++IPR002223///Pancreatic trypsin inhibitor Kunitz domain","[SPIT2_HUMAN|Reviewed]RecName: Full=Kunitz-type protease inhibitor 2; AltName: Full=Hepatocyte growth factor activator inhibitor type 2; Short=HAI-2; AltName: Full=Placental bikunin; Flags: Precursor;+++[A0A140VJV6_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 183 {ECO:0000313|EMBL:AEE61093.1};+++[K7EJS4_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465301}; Flags: Fragment;+++[K7EKC8_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465561}; Flags: Fragment;+++[K7EKQ0_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000465721}; Flags: Fragment;+++[K7EM91_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000466407};+++[K7ES27_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000468519}; Flags: Fragment;+++[K7ESI5_HUMAN|Unreviewed]SubName: Full=Kunitz-type protease inhibitor 2 {ECO:0000313|Ensembl:ENSP00000468728}; Flags: Fragment;+++[Q6LEU8_HUMAN|Unreviewed]SubName: Full=SPINT2 protein {ECO:0000313|EMBL:CAG28532.1}; Flags: Fragment;"]
[10654,"'PMVK'",239,180,209.5,"00900///Terpenoid backbone biosynthesis+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++04146///Peroxisome","H01933///Porokeratosis","M00095///C5 isoprenoid biosynthesis, mevalonate pathway","R03245///ATP:(R)-5-phosphomevalonate phosphotransferase   ATP + (R)-5-Phosphomevalonate <=> ADP + (R)-5-Diphosphomevalonate","GO:0070062///extracellular exosome+++GO:0005777///peroxisome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0004631///phosphomevalonate kinase activity+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006629///lipid metabolic process+++GO:0070723///response to cholesterol+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0019287///isopentenyl diphosphate biosynthetic process, mevalonate pathway+++GO:0006694///steroid biosynthetic process+++GO:0016126///sterol biosynthetic process+++GO:0016310///phosphorylation+++GO:0008203///cholesterol metabolic process+++GO:0008202///steroid metabolic process+++GO:0008299///isoprenoid biosynthetic process+++GO:0006695///cholesterol biosynthetic process","IPR005919///Higher eukaryotic phosphomevalonate kinase+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[PMVK_HUMAN|Reviewed]RecName: Full=Phosphomevalonate kinase; Short=PMKase; Short=hPMK; EC=2.7.4.2;+++[Q6FGV9_HUMAN|Unreviewed]SubName: Full=PMVK protein {ECO:0000313|EMBL:CAG46795.1}; SubName: Full=Phosphomevalonate kinase, isoform CRA_a {ECO:0000313|EMBL:EAW53177.1}; SubName: Full=Testis tissue sperm-binding protein Li 95mP {ECO:0000313|EMBL:AEE61315.1}; SubName: Full=cDNA, FLJ93228, Homo sapiens phosphomevalonate kinase (PMVK), mRNA {ECO:0000313|EMBL:BAG35661.1}; Flags: Fragment;"]
[10655,"'DMRT2'",1,0,0.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005575///cellular_component","GO:0043565///sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003674///molecular_function+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding","GO:0014807///regulation of somitogenesis+++GO:0008150///biological_process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048706///embryonic skeletal system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:2000287///positive regulation of myotome development","IPR036407///DM DNA-binding domain superfamily+++IPR001275///DM DNA-binding domain+++IPR026607///DMRT/protein doublesex/protein male abnormal 3","[DMRT2_HUMAN|Reviewed]RecName: Full=Doublesex- and mab-3-related transcription factor 2; AltName: Full=Doublesex-like 2 protein; Short=DSXL-2;+++[A0A0A0MR18_HUMAN|Unreviewed]SubName: Full=Doublesex- and mab-3-related transcription factor 2 {ECO:0000313|Ensembl:ENSP00000305785};+++[Q05C20_HUMAN|Unreviewed]SubName: Full=DMRT2 protein {ECO:0000313|EMBL:AAH30204.1}; SubName: Full=cDNA FLJ77088, highly similar to Homo sapiens doublesex and mab-3 related transcription factor 2 (DMRT2), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF83483.1};+++[Q5HYK2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp313M1824 {ECO:0000313|EMBL:CAI46061.1};"]
[10656,"'KHDRBS3'",384,334,359,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0019904///protein domain specific binding+++GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0051259///protein complex oligomerization+++GO:0006397///mRNA processing+++GO:0048024///regulation of mRNA splicing, via spliceosome","IPR032335///Sam68, tyrosine-rich domain+++IPR004087///K Homology domain+++IPR036612///K Homology domain, type 1 superfamily+++IPR032571///KHDRBS, Qua1 domain+++IPR004088///K Homology domain, type 1","[KHDR3_HUMAN|Reviewed]RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3; AltName: Full=RNA-binding protein T-Star; AltName: Full=Sam68-like mammalian protein 2; Short=SLM-2; AltName: Full=Sam68-like phosphotyrosine protein;+++[E5RG12_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000430284}; Flags: Fragment;+++[E5RHD3_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000428607};+++[E5RJZ9_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000431022}; Flags: Fragment;+++[H0YAQ1_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000427841}; Flags: Fragment;+++[H0YAQ3_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000427851}; Flags: Fragment;+++[H0YB45_HUMAN|Unreviewed]SubName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 3 {ECO:0000313|Ensembl:ENSP00000428643}; Flags: Fragment;+++[L8EAJ0_HUMAN|Unreviewed]SubName: Full=Alternative protein KHDRBS3 {ECO:0000313|EMBL:CCQ43363.1};+++[L8EC47_HUMAN|Unreviewed]SubName: Full=Alternative protein KHDRBS3 {ECO:0000313|EMBL:CCQ42937.1};"]
[10657,"'KHDRBS1'",1109,984,1046.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070618///Grb2-Sos complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0008266///poly(U) RNA binding+++GO:0003676///nucleic acid binding+++GO:0042802///identical protein binding+++GO:0005070///SH3/SH2 adaptor activity+++GO:0003677///DNA binding+++GO:0044877///protein-containing complex binding+++GO:0005515///protein binding+++GO:0017124///SH3 domain binding+++GO:0019904///protein domain specific binding+++GO:0008143///poly(A) binding+++GO:0003723///RNA binding","GO:0007049///cell cycle+++GO:0031647///regulation of protein stability+++GO:0045948///positive regulation of translational initiation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006397///mRNA processing+++GO:0007165///signal transduction+++GO:0046831///regulation of RNA export from nucleus+++GO:0007166///cell surface receptor signaling pathway+++GO:0007050///cell cycle arrest+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0008283///cell proliferation+++GO:0007283///spermatogenesis+++GO:0046833///positive regulation of RNA export from nucleus+++GO:0051259///protein complex oligomerization+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0009967///positive regulation of signal transduction+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","IPR032335///Sam68, tyrosine-rich domain+++IPR032571///KHDRBS, Qua1 domain+++IPR036612///K Homology domain, type 1 superfamily+++IPR004087///K Homology domain+++IPR004088///K Homology domain, type 1","[KHDR1_HUMAN|Reviewed]RecName: Full=KH domain-containing, RNA-binding, signal transduction-associated protein 1; AltName: Full=GAP-associated tyrosine phosphoprotein p62; AltName: Full=Src-associated in mitosis 68 kDa protein; Short=Sam68; AltName: Full=p21 Ras GTPase-activating protein-associated p62; AltName: Full=p68;+++[B4E043_HUMAN|Unreviewed]SubName: Full=KH domain containing, RNA binding, signal transduction associated 1, isoform CRA_b {ECO:0000313|EMBL:EAX07575.1}; SubName: Full=cDNA FLJ52899, highly similar to KH domain-containing, RNA-binding, signaltransduction-associated protein 1 {ECO:0000313|EMBL:BAG64305.1};"]
[10658,"'CELF1'",380,603,491.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0042835///BRE binding+++GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0005515///protein binding+++GO:0036002///pre-mRNA binding+++GO:0003676///nucleic acid binding+++GO:0031369///translation initiation factor binding","GO:0007281///germ cell development+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0017148///negative regulation of translation+++GO:0006376///mRNA splice site selection+++GO:0043484///regulation of RNA splicing+++GO:0006397///mRNA processing+++GO:0040018///positive regulation of multicellular organism growth+++GO:0016246///RNA interference+++GO:0008380///RNA splicing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0007286///spermatid development","IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR034199///CELF1/2, RNA recognition motif 3+++IPR035979///RNA-binding domain superfamily+++IPR034198///CELF1/2, RNA recognition motif 2+++IPR034196///CELF1/2, RNA recognition motif 1","[CELF1_HUMAN|Reviewed]RecName: Full=CUGBP Elav-like family member 1; Short=CELF-1; AltName: Full=50 kDa nuclear polyadenylated RNA-binding protein; AltName: Full=Bruno-like protein 2; AltName: Full=CUG triplet repeat RNA-binding protein 1; Short=CUG-BP1; AltName: Full=CUG-BP- and ETR-3-like factor 1; AltName: Full=Deadenylation factor CUG-BP; AltName: Full=Embryo deadenylation element-binding protein homolog; Short=EDEN-BP homolog; AltName: Full=RNA-binding protein BRUNOL-2;+++[E9PKA1_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000435423}; Flags: Fragment;+++[E9PKU1_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000435320}; Flags: Fragment;+++[E9PQK4_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000436191}; Flags: Fragment;+++[E9PSH0_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000433986}; Flags: Fragment;+++[F5H0D8_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000438044}; Flags: Fragment;+++[F5H3J7_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000438862}; Flags: Fragment;+++[F5H4Y5_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000444825}; Flags: Fragment;+++[F5H7M7_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000442415}; Flags: Fragment;+++[G5EA30_HUMAN|Unreviewed]SubName: Full=CUG triplet repeat, RNA binding protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW67908.1}; SubName: Full=CUGBP Elav-like family member 1 {ECO:0000313|Ensembl:ENSP00000436864};"]
[10659,"'CELF2'",1109,1375,1242,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005634///nucleus","GO:0003729///mRNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0036002///pre-mRNA binding","GO:0006397///mRNA processing+++GO:0008016///regulation of heart contraction+++GO:0006376///mRNA splice site selection+++GO:0006396///RNA processing+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR035979///RNA-binding domain superfamily+++IPR002343///Paraneoplastic encephalomyelitis antigen+++IPR034199///CELF1/2, RNA recognition motif 3+++IPR034198///CELF1/2, RNA recognition motif 2+++IPR034196///CELF1/2, RNA recognition motif 1","[CELF2_HUMAN|Reviewed]RecName: Full=CUGBP Elav-like family member 2; Short=CELF-2; AltName: Full=Bruno-like protein 3; AltName: Full=CUG triplet repeat RNA-binding protein 2; Short=CUG-BP2; AltName: Full=CUG-BP- and ETR-3-like factor 2; AltName: Full=ELAV-type RNA-binding protein 3; Short=ETR-3; AltName: Full=Neuroblastoma apoptosis-related RNA-binding protein; Short=hNAPOR; AltName: Full=RNA-binding protein BRUNOL-3;+++[A0A0J9YX66_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000488268};+++[A0A0J9YXJ0_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000488422};+++[A0A0J9YXK1_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000488438};+++[A0A1B0GU44_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000489955};+++[A0A1B0GUN8_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000490185};+++[B4DDE7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54335, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG56708.1};+++[B4DIB6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51739, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG58428.1};+++[B4DT00_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50655, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG61812.1};+++[B4DZ01_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52370, highly similar to Homo sapiens CUG triplet repeat, RNA binding protein 2 (CUGBP2), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG63913.1};+++[E9PC62_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000443926};+++[Q5VZZ6_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000346971};+++[V9GY47_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000476392};+++[V9GYD9_HUMAN|Unreviewed]SubName: Full=CUGBP Elav-like family member 2 {ECO:0000313|Ensembl:ENSP00000476656};"]
[1066,"'CES1'",42,38,40,"01100///Metabolic pathways+++00983///Drug metabolism - other enzymes",null,null,"R08251///isoniazid amidohydrolase   Isoniazid + H2O <=> Isonicotinic acid + Hydrazine+++R06728///cocaine benzoylhydrolase   Cocaine + H2O <=> Ecgonine methyl ester + Benzoate+++R08258///NPC + H2O <=> SN-38 + 4-Amino-1-piperidinecarboxylic acid+++R08249///N-acetylisoniazid amidohydrolase   N-Acetylisoniazid + H2O <=> Acetylhydrazine + Isonicotinic acid+++R08255///Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid+++R08220///capecitabine hydrolase   Capecitabine + H2O <=> 5'-Deoxy-5-fluorocytidine + 1-Pentanol + CO2","GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005615///extracellular space+++GO:0005788///endoplasmic reticulum lumen","GO:0016787///hydrolase activity+++GO:0004806///triglyceride lipase activity+++GO:0004771///sterol esterase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0047374///methylumbelliferyl-acetate deacetylase activity","GO:0006805///xenobiotic metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0006695///cholesterol biosynthetic process+++GO:0051791///medium-chain fatty acid metabolic process+++GO:0009056///catabolic process+++GO:0090122///cholesterol ester hydrolysis involved in cholesterol transport+++GO:0009636///response to toxic substance+++GO:0030855///epithelial cell differentiation+++GO:0016042///lipid catabolic process","IPR002018///Carboxylesterase, type B+++IPR019826///Carboxylesterase type B, active site+++IPR019819///Carboxylesterase type B, conserved site+++IPR029058///Alpha/Beta hydrolase fold","[EST1_HUMAN|Reviewed]RecName: Full=Liver carboxylesterase 1; AltName: Full=Acyl-coenzyme A:cholesterol acyltransferase; Short=ACAT; AltName: Full=Brain carboxylesterase hBr1; AltName: Full=Carboxylesterase 1; Short=CE-1; Short=hCE-1; EC=3.1.1.1 {ECO:0000269|PubMed:7980644, ECO:0000269|PubMed:9169443, ECO:0000269|PubMed:9490062}; AltName: Full=Cocaine carboxylesterase; AltName: Full=Egasyn; AltName: Full=HMSE; AltName: Full=Methylumbelliferyl-acetate deacetylase 1; EC=3.1.1.56 {ECO:0000269|PubMed:9169443}; AltName: Full=Monocyte/macrophage serine esterase; AltName: Full=Retinyl ester hydrolase; Short=REH; AltName: Full=Serine esterase 1; AltName: Full=Triacylglycerol hydrolase; Short=TGH; Flags: Precursor;+++[A0A140TA63_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000458773}; Flags: Fragment;+++[H3BQR4_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000455902}; Flags: Fragment;+++[H3BQV8_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000455959}; Flags: Fragment;+++[H3BSU0_HUMAN|Unreviewed]SubName: Full=Liver carboxylesterase 1 {ECO:0000313|Ensembl:ENSP00000456865}; Flags: Fragment;"]
[10661,"'KLF1'",1,0,0.5,null,"H00917///Congenital dyserythropoietic anemias (CDAs)",null,null,"GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:1901653///cellular response to peptide+++GO:0030218///erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060135///maternal process involved in female pregnancy","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR031784///Krueppel-like factor 1, transactivation domain 2+++IPR031786///Krueppel-like factor 1, transactivation domain 1","[KLF1_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 1; AltName: Full=Erythroid krueppel-like transcription factor; Short=EKLF;+++[A0A0U4CJG7_HUMAN|Unreviewed]SubName: Full=Truncated EKLF {ECO:0000313|EMBL:ALX18093.1}; Flags: Fragment;+++[A0A0U4D3U3_HUMAN|Unreviewed]SubName: Full=EKLF {ECO:0000313|EMBL:ALX18091.1}; Flags: Fragment;+++[A0A0U4DAW6_HUMAN|Unreviewed]SubName: Full=Truncated EKLF {ECO:0000313|EMBL:ALX18090.1}; Flags: Fragment;+++[A0A0U4DXB2_HUMAN|Unreviewed]SubName: Full=Truncated EKLF {ECO:0000313|EMBL:ALX18089.1}; Flags: Fragment;+++[A0A0U4EBD4_HUMAN|Unreviewed]SubName: Full=Truncated EKLF {ECO:0000313|EMBL:ALX18094.1}; Flags: Fragment;+++[A0A172M5U0_HUMAN|Unreviewed]SubName: Full=Truncated erythroid Kruppel-like factor 1 {ECO:0000313|EMBL:ANC85230.1}; Flags: Fragment;+++[A0A1U9WYY8_HUMAN|Unreviewed]SubName: Full=KLF1 {ECO:0000313|EMBL:AQY61598.1}; Flags: Fragment;+++[A0A223PZB5_HUMAN|Unreviewed]SubName: Full=EKLF {ECO:0000313|EMBL:ASU50672.1};+++[B7TQ30_HUMAN|Unreviewed]SubName: Full=Erythroid Kruppel-like factor 1 variant {ECO:0000313|EMBL:ACJ26762.1}; Flags: Fragment;+++[B7TQ31_HUMAN|Unreviewed]SubName: Full=Erythroid Kruppel-like factor 1 variant {ECO:0000313|EMBL:ACJ26763.1}; Flags: Fragment;+++[B9UZC3_HUMAN|Unreviewed]SubName: Full=Erythroid Kruppel-like factor 1 variant {ECO:0000313|EMBL:ACM18112.1}; Flags: Fragment;+++[B9UZC4_HUMAN|Unreviewed]SubName: Full=Erythroid Kruppel-like factor 1 variant {ECO:0000313|EMBL:ACM18113.1}; Flags: Fragment;+++[B9UZC5_HUMAN|Unreviewed]SubName: Full=Erythroid Kruppel-like factor 1 variant {ECO:0000313|EMBL:ACM18114.1}; Flags: Fragment;+++[B9UZC6_HUMAN|Unreviewed]SubName: Full=Erythroid Kruppel-like factor 1 variant {ECO:0000313|EMBL:ACM18115.1}; Flags: Fragment;+++[B9UZC7_HUMAN|Unreviewed]SubName: Full=Erythroid Kruppel-like factor 1 variant {ECO:0000313|EMBL:ACM18116.1}; Flags: Fragment;+++[K7VKE0_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 1 {ECO:0000313|EMBL:AFW90650.1};"]
[10664,"'CTCF'",423,439,431,{"$nulls":4},"GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0000775///chromosome, centromeric region","GO:0044212///transcription regulatory region DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003714///transcription corepressor activity+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0043035///chromatin insulator sequence binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071459///protein localization to chromosome, centromeric region+++GO:0008285///negative regulation of cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0010628///positive regulation of gene expression+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006325///chromatin organization+++GO:0035065///regulation of histone acetylation+++GO:0040030///regulation of molecular function, epigenetic+++GO:0010216///maintenance of DNA methylation+++GO:0070602///regulation of centromeric sister chromatid cohesion+++GO:0006306///DNA methylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0040029///regulation of gene expression, epigenetic+++GO:0031060///regulation of histone methylation+++GO:0010629///negative regulation of gene expression+++GO:0016584///nucleosome positioning+++GO:0006349///regulation of gene expression by genetic imprinting+++GO:0007059///chromosome segregation","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[CTCF_HUMAN|Reviewed]RecName: Full=Transcriptional repressor CTCF; AltName: Full=11-zinc finger protein; AltName: Full=CCCTC-binding factor; AltName: Full=CTCFL paralog;+++[A0A2R8Y595_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000494358};+++[A0A2R8Y6C1_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000495115}; Flags: Fragment;+++[A0A2R8Y6Z6_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000495923}; Flags: Fragment;+++[A0A2R8YFL0_HUMAN|Unreviewed]SubName: Full=Transcriptional repressor CTCF {ECO:0000313|Ensembl:ENSP00000495218};"]
[10666,"'CD226'",3,1,2,"04514///Cell adhesion molecules (CAMs)","H00408///Type I diabetes mellitus",null,null,"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0009897///external side of plasma membrane+++GO:0045121///membrane raft+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005178///integrin binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0050839///cell adhesion molecule binding","GO:0032729///positive regulation of interferon-gamma production+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0007165///signal transduction+++GO:0060369///positive regulation of Fc receptor mediated stimulatory signaling pathway+++GO:0001816///cytokine production+++GO:0007155///cell adhesion+++GO:0002891///positive regulation of immunoglobulin mediated immune response+++GO:0002729///positive regulation of natural killer cell cytokine production+++GO:0050776///regulation of immune response+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0033005///positive regulation of mast cell activation+++GO:0008037///cell recognition+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity","IPR007110///Immunoglobulin-like domain+++IPR003598///Immunoglobulin subtype 2+++IPR013783///Immunoglobulin-like fold+++IPR013106///Immunoglobulin V-set domain+++IPR003599///Immunoglobulin subtype+++IPR036179///Immunoglobulin-like domain superfamily","[CD226_HUMAN|Reviewed]RecName: Full=CD226 antigen; AltName: Full=DNAX accessory molecule 1; Short=DNAM-1; AltName: CD_antigen=CD226; Flags: Precursor;+++[J3QKM7_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000463152}; Flags: Fragment;+++[J3QL19_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000463335}; Flags: Fragment;+++[J3QQW1_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000463927}; Flags: Fragment;+++[J3QR77_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000464084};+++[J3QRQ4_HUMAN|Unreviewed]SubName: Full=CD226 antigen {ECO:0000313|Ensembl:ENSP00000464334}; Flags: Fragment;"]
[10667,"'FARS2'",164,146,155,"00970///Aminoacyl-tRNA biosynthesis","H00266///Hereditary spastic paraplegia (SPG)+++H00891///Combined oxidative phosphorylation deficiency (COXPD)","M00359///Aminoacyl-tRNA biosynthesis, eukaryotes+++M00360///Aminoacyl-tRNA biosynthesis, prokaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm","GO:0016874///ligase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0000049///tRNA binding+++GO:0004826///phenylalanine-tRNA ligase activity","GO:0006418///tRNA aminoacylation for protein translation+++GO:0006412///translation+++GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0008033///tRNA processing","IPR004530///Phenylalanyl-tRNA synthetase, class IIc, mitochondrial+++IPR006195///Aminoacyl-tRNA synthetase, class II+++IPR036690///Ferrodoxin-fold anticodon-binding domain superfamily+++IPR002319///Phenylalanyl-tRNA synthetase+++IPR005121///Ferrodoxin-fold anticodon-binding domain","[SYFM_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase, mitochondrial; EC=6.1.1.20 {ECO:0000269|PubMed:19549855, ECO:0000269|PubMed:22833457}; AltName: Full=Phenylalanyl-tRNA synthetase; Short=PheRS; Flags: Precursor;+++[Q5JRF7_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000392525}; Flags: Fragment;+++[R4GMX6_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase, mitochondrial {ECO:0000313|Ensembl:ENSP00000473394}; Flags: Fragment;"]
[10668,"'CGRRF1'",89,78,83.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0046872///metal ion binding","GO:0007049///cell cycle+++GO:0007050///cell cycle arrest+++GO:0008285///negative regulation of cell proliferation","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type","[CGRF1_HUMAN|Reviewed]RecName: Full=Cell growth regulator with RING finger domain protein 1; AltName: Full=Cell growth regulatory gene 19 protein; AltName: Full=RING finger protein 197;+++[G3V229_HUMAN|Unreviewed]SubName: Full=Cell growth regulator with RING finger domain protein 1 {ECO:0000313|Ensembl:ENSP00000450430}; Flags: Fragment;+++[G3V2K9_HUMAN|Unreviewed]SubName: Full=Cell growth regulator with RING finger domain protein 1 {ECO:0000313|Ensembl:ENSP00000450728};+++[G3V412_HUMAN|Unreviewed]SubName: Full=Cell growth regulator with RING finger domain protein 1 {ECO:0000313|Ensembl:ENSP00000451532};+++[M0QZQ7_HUMAN|Unreviewed]SubName: Full=Cell growth regulator with RING finger domain protein 1 {ECO:0000313|Ensembl:ENSP00000470702}; Flags: Fragment;"]
[10669,"'CGREF1'",358,302,330,"01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++00051///Fructose and mannose metabolism","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,"R00866///ATP:D-fructose 1-phosphotransferase ATP + D-Fructose <=> ADP + D-Fructose 1-phosphate+++R03819///ATP:sedoheptulose 1-phosphotransferase ATP + Sedoheptulose <=> ADP + Sedoheptulose 1-phosphate","GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0046872///metal ion binding","GO:0008285///negative regulation of cell proliferation+++GO:0007050///cell cycle arrest+++GO:0007049///cell cycle+++GO:0007155///cell adhesion","IPR018247///EF-Hand 1, calcium-binding site+++IPR002048///EF-hand domain+++IPR011992///EF-hand domain pair","[CGRE1_HUMAN|Reviewed]RecName: Full=Cell growth regulator with EF hand domain protein 1; AltName: Full=Cell growth regulatory gene 11 protein; AltName: Full=Hydrophobestin; Flags: Precursor;+++[F8WE80_HUMAN|Unreviewed]SubName: Full=Cell growth regulator with EF hand domain protein 1 {ECO:0000313|Ensembl:ENSP00000394306};"]
[10670,"'RRAGA'",1165,1026,1095.5,"04150///mTOR signaling pathway+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:1990130///GATOR1 complex+++GO:0005634///nucleus+++GO:0034448///EGO complex+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0005737///cytoplasm+++GO:1990131///Gtr1-Gtr2 GTPase complex","GO:0046982///protein heterodimerization activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0042803///protein homodimerization activity+++GO:0051219///phosphoprotein binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0005515///protein binding","GO:0010507///negative regulation of autophagy+++GO:0045919///positive regulation of cytolysis+++GO:1904263///positive regulation of TORC1 signaling+++GO:0019048///modulation by virus of host morphology or physiology+++GO:0007050///cell cycle arrest+++GO:0009267///cellular response to starvation+++GO:0016032///viral process+++GO:0006915///apoptotic process+++GO:0008219///cell death+++GO:0016567///protein ubiquitination+++GO:0032008///positive regulation of TOR signaling+++GO:0010506///regulation of autophagy+++GO:0034613///cellular protein localization+++GO:0016241///regulation of macroautophagy+++GO:0071230///cellular response to amino acid stimulus+++GO:0034198///cellular response to amino acid starvation","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR039397///RagA/B+++IPR006762///Gtr1/RagA G protein","[RRAGA_HUMAN|Reviewed]RecName: Full=Ras-related GTP-binding protein A {ECO:0000305}; Short=Rag A {ECO:0000303|PubMed:11073942}; Short=RagA {ECO:0000303|PubMed:7499430}; AltName: Full=Adenovirus E3 14.7 kDa-interacting protein 1 {ECO:0000303|PubMed:8995684}; AltName: Full=FIP-1 {ECO:0000303|PubMed:8995684};"]
[106707243,"'PRH1-TAS2R14'",5.67,1.38,3.525,"04742///Taste transduction","H01611///Alcohol dependence",null,null,"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0008527///taste receptor activity+++GO:0033038///bitter taste receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0001580///detection of chemical stimulus involved in sensory perception of bitter taste+++GO:0007186///G protein-coupled receptor signaling pathway","IPR007960///Taste receptor type 2","[Q6ZW62_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41554 fis, clone COLON2005772, highly similar to Homo sapiens candidate taste receptor T2R14 gene {ECO:0000313|EMBL:BAC85643.1};"]
[10671,"'DCTN6'",345,361,353,"04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0000775///chromosome, centromeric region+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005869///dynactin complex+++GO:0005813///centrosome+++GO:0000777///condensed chromosome kinetochore+++GO:0000776///kinetochore",null,"GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II","IPR001451///Hexapeptide repeat+++IPR011004///Trimeric LpxA-like superfamily+++IPR027777///Dynactin subunit 6","[DCTN6_HUMAN|Reviewed]RecName: Full=Dynactin subunit 6; AltName: Full=Dynactin subunit p27; AltName: Full=Protein WS-3;+++[E5RFU3_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 6 {ECO:0000313|Ensembl:ENSP00000427955};+++[E5RGW9_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 6 {ECO:0000313|Ensembl:ENSP00000430109};+++[E5RIK5_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 6 {ECO:0000313|Ensembl:ENSP00000429408};+++[E5RK00_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 6 {ECO:0000313|Ensembl:ENSP00000431017};"]
[10672,"'GNA13'",584,744,664,"05163///Human cytomegalovirus infection+++04371///Apelin signaling pathway+++04810///Regulation of actin cytoskeleton+++04611///Platelet activation+++04730///Long-term depression+++04928///Parathyroid hormone synthesis, secretion and action+++04270///Vascular smooth muscle contraction+++04022///cGMP-PKG signaling pathway+++04072///Phospholipase D signaling pathway+++05200///Pathways in cancer+++04071///Sphingolipid signaling pathway",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0042470///melanosome+++GO:0031526///brush border membrane+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005834///heterotrimeric G-protein complex","GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding+++GO:0001664///G protein-coupled receptor binding+++GO:0031752///D5 dopamine receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0019001///guanyl nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity","GO:0031584///activation of phospholipase D activity+++GO:0008360///regulation of cell shape+++GO:0007266///Rho protein signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0035556///intracellular signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0030154///cell differentiation+++GO:0007165///signal transduction+++GO:0030334///regulation of cell migration+++GO:0030168///platelet activation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0001525///angiogenesis+++GO:0001701///in utero embryonic development+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR011025///G protein alpha subunit, helical insertion+++IPR001019///Guanine nucleotide binding protein (G-protein), alpha subunit+++IPR000469///G-protein alpha subunit, group 12/13","[GNA13_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein subunit alpha-13; Short=G alpha-13; Short=G-protein subunit alpha-13;+++[A0A024R8M0_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein (G protein), alpha 13, isoform CRA_a {ECO:0000313|EMBL:EAW88995.1};"]
[10673,"'TNFSF13B'",2,9,5.5,"05323///Rheumatoid arthritis+++04060///Cytokine-cytokine receptor interaction+++04064///NF-kappa B signaling pathway+++04672///Intestinal immune network for IgA production",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005694///chromosome+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0031965///nuclear membrane+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center","GO:0004842///ubiquitin-protein transferase activity+++GO:0005164///tumor necrosis factor receptor binding+++GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding","GO:0051726///regulation of cell cycle+++GO:0006260///DNA replication+++GO:0031295///T cell costimulation+++GO:0007165///signal transduction+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0002376///immune system process+++GO:0008284///positive regulation of cell proliferation+++GO:0045732///positive regulation of protein catabolic process+++GO:0019985///translesion synthesis+++GO:0001782///B cell homeostasis+++GO:0008283///cell proliferation+++GO:0016567///protein ubiquitination+++GO:0010469///regulation of signaling receptor activity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0000209///protein polyubiquitination+++GO:0002636///positive regulation of germinal center formation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006955///immune response+++GO:0048305///immunoglobulin secretion+++GO:0042102///positive regulation of T cell proliferation+++GO:0031296///B cell costimulation+++GO:0043687///post-translational protein modification+++GO:0050776///regulation of immune response+++GO:0006513///protein monoubiquitination+++GO:0009411///response to UV+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:0030890///positive regulation of B cell proliferation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle","IPR008983///Tumour necrosis factor-like domain superfamily+++IPR006052///Tumour necrosis factor domain","[TN13B_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 13B; AltName: Full=B lymphocyte stimulator; Short=BLyS; AltName: Full=B-cell-activating factor; AltName: Full=BAFF; AltName: Full=Dendritic cell-derived TNF-like molecule; AltName: Full=TNF- and APOL-related leukocyte expressed ligand 1; Short=TALL-1; AltName: CD_antigen=CD257; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 13b, membrane form; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 13b, soluble form;+++[A0A0U5J7Q1_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 7A {ECO:0000313|EMBL:CTQ86090.1};+++[Q8IZI4_HUMAN|Unreviewed]SubName: Full=B-lymphocyte stimulator {ECO:0000313|EMBL:AAN08424.1}; Flags: Fragment;+++[Q8IZI5_HUMAN|Unreviewed]SubName: Full=B-lymphocyte stimulator {ECO:0000313|EMBL:AAN08423.1}; Flags: Fragment;+++[Q8IZI6_HUMAN|Unreviewed]SubName: Full=B-lymphocyte stimulator {ECO:0000313|EMBL:AAN08422.1}; Flags: Fragment;"]
[10675,"'CSPG5'",183,137,160,{"$nulls":4},"GO:0030660///Golgi-associated vesicle membrane+++GO:0099055///integral component of postsynaptic membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005796///Golgi lumen+++GO:0005789///endoplasmic reticulum membrane+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0043202///lysosomal lumen+++GO:0098982///GABA-ergic synapse+++GO:0000139///Golgi membrane","GO:0005515///protein binding+++GO:0008083///growth factor activity","GO:0040008///regulation of growth+++GO:0046907///intracellular transport+++GO:0030154///cell differentiation+++GO:0030207///chondroitin sulfate catabolic process+++GO:0099550///trans-synaptic signaling, modulating synaptic transmission+++GO:0030206///chondroitin sulfate biosynthetic process+++GO:0007399///nervous system development+++GO:0030208///dermatan sulfate biosynthetic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007275///multicellular organism development+++GO:0010469///regulation of signaling receptor activity+++GO:2000300///regulation of synaptic vesicle exocytosis","IPR010555///CSPG5, sulphate attachment domain+++IPR009505///Neural chondroitin sulphate proteoglycan cytoplasmic","[CSPG5_HUMAN|Reviewed]RecName: Full=Chondroitin sulfate proteoglycan 5; AltName: Full=Acidic leucine-rich EGF-like domain-containing brain protein; AltName: Full=Neuroglycan C; Flags: Precursor;+++[A0A087WUT8_HUMAN|Unreviewed]SubName: Full=Chondroitin sulfate proteoglycan 5 {ECO:0000313|Ensembl:ENSP00000478923};+++[B7Z2E0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54649, highly similar to Chondroitin sulfate proteoglycan 5 {ECO:0000313|EMBL:BAH11826.1};"]
[10677,"'AVIL'",6,5,5.5,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0043005///neuron projection+++GO:0030424///axon+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0060271///cilium assembly+++GO:0051693///actin filament capping+++GO:0007010///cytoskeleton organization+++GO:0010976///positive regulation of neuron projection development+++GO:0007399///nervous system development","IPR036886///Villin headpiece domain superfamily+++IPR007123///Gelsolin-like domain+++IPR003128///Villin headpiece+++IPR036180///Gelsolin-like domain superfamily+++IPR029006///ADF-H/Gelsolin-like domain superfamily+++IPR007122///Villin/Gelsolin","[AVIL_HUMAN|Reviewed]RecName: Full=Advillin; AltName: Full=p92;+++[F8VNY0_HUMAN|Unreviewed]SubName: Full=Advillin {ECO:0000313|Ensembl:ENSP00000450188};+++[F8VVU1_HUMAN|Unreviewed]SubName: Full=Advillin {ECO:0000313|Ensembl:ENSP00000449239}; Flags: Fragment;"]
[10678,"'B3GNT2'",222,263,242.5,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00533///Glycosaminoglycan biosynthesis - keratan sulfate+++01100///Metabolic pathways",null,null,"R04659///UDP-N-acetyl-D-glucosamine:beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide beta-1,3-acetylglucosaminyltransferase   UDP-N-acetyl-alpha-D-glucosamine + beta-D-Galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide <=> UDP + N-Acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide+++R05974///UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + nLc7Cer+++R05975///UDP-N-acetyl-D-glucosamine + Paragloboside <=> UDP + nLc5Cer","GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0008378///galactosyltransferase activity+++GO:0016740///transferase activity+++GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008376///acetylgalactosaminyltransferase activity","GO:0018146///keratan sulfate biosynthetic process+++GO:0030311///poly-N-acetyllactosamine biosynthetic process+++GO:0007411///axon guidance+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0006486///protein glycosylation+++GO:0007608///sensory perception of smell+++GO:0016266///O-glycan processing","IPR002659///Glycosyl transferase, family 31","[B3GN2_HUMAN|Reviewed]RecName: Full=N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2; EC=2.4.1.149 {ECO:0000269|PubMed:11042166, ECO:0000269|PubMed:25279697, ECO:0000269|PubMed:9892646}; AltName: Full=Beta-1,3-N-acetylglucosaminyltransferase 1; Short=BGnT-1; Short=Beta-1,3-Gn-T1; Short=Beta3Gn-T1; AltName: Full=Beta-1,3-galactosyltransferase 7; Short=Beta-1,3-GalTase 7; Short=Beta3Gal-T7; Short=Beta3GalT7; Short=b3Gal-T7; AltName: Full=Beta-3-Gx-T7; AltName: Full=UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7; AltName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2; Short=BGnT-2; Short=Beta-1,3-Gn-T2; Short=Beta-1,3-N-acetylglucosaminyltransferase 2; Short=Beta3Gn-T2; AltName: Full=UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7;"]
[10681,"'GNB5'",301,286,293.5,"04726///Serotonergic synapse+++05032///Morphine addiction+++05034///Alcoholism+++04724///Glutamatergic synapse+++04723///Retrograde endocannabinoid signaling+++04713///Circadian entrainment+++04725///Cholinergic synapse+++04014///Ras signaling pathway+++05200///Pathways in cancer+++04062///Chemokine signaling pathway+++04926///Relaxin signaling pathway+++04151///PI3K-Akt signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05163///Human cytomegalovirus infection+++04728///Dopaminergic synapse+++04371///Apelin signaling pathway+++04727///GABAergic synapse",{"$nulls":3},"GO:0098793///presynapse+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005886///plasma membrane+++GO:1902773///GTPase activator complex","GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0031682///G-protein gamma-subunit binding+++GO:0051087///chaperone binding+++GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0006457///protein folding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0007212///dopamine receptor signaling pathway+++GO:1901386///negative regulation of voltage-gated calcium channel activity","IPR001680///WD40 repeat+++IPR020472///G-protein beta WD-40 repeat+++IPR016346///Guanine nucleotide-binding protein, beta subunit+++IPR001632///G-protein, beta subunit+++IPR017986///WD40-repeat-containing domain+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR036322///WD40-repeat-containing domain superfamily+++IPR019775///WD40 repeat, conserved site","[GNB5_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein subunit beta-5; AltName: Full=Gbeta5; AltName: Full=Transducin beta chain 5;+++[A0A024R5R9_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein (G protein), beta 5, isoform CRA_a {ECO:0000313|EMBL:EAW77442.1};+++[A0A024R5V3_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein (G protein), beta 5, isoform CRA_b {ECO:0000313|EMBL:EAW77443.1};+++[A0A024R5Y0_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide binding protein (G protein), beta 5, isoform CRA_c {ECO:0000313|EMBL:EAW77444.1};+++[H0YLU1_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein subunit beta-5 {ECO:0000313|Ensembl:ENSP00000453339}; Flags: Fragment;+++[H0YNW7_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein subunit beta-5 {ECO:0000313|Ensembl:ENSP00000454185};+++[Q96F32_HUMAN|Unreviewed]SubName: Full=GNB5 protein {ECO:0000313|EMBL:AAH11671.1}; SubName: Full=Guanine nucleotide-binding protein subunit beta-5 {ECO:0000313|Ensembl:ENSP00000453176};"]
[10682,"'EBP'",395,267,331,"01100///Metabolic pathways+++00100///Steroid biosynthesis+++01110///Biosynthesis of secondary metabolites","H01194///X-linked chondrodysplasia punctata","M00101///Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol","R03353///5alpha-Cholest-7-en-3beta-ol delta7-delta8-isomerase   Lathosterol <=> 5alpha-Cholest-8-en-3beta-ol+++R04804///delta8,24-Cholestadien-3beta-ol delta7-delta8-isomerase   Zymosterol <=> 5alpha-Cholesta-7,24-dien-3beta-ol+++R07484///4alpha-Methylfecosterol <=> 24-Methylenelophenol","GO:0005887///integral component of plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005635///nuclear envelope+++GO:0005789///endoplasmic reticulum membrane","GO:0004769///steroid delta-isomerase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0000247///C-8 sterol isomerase activity+++GO:0047750///cholestenol delta-isomerase activity+++GO:0015238///drug transmembrane transporter activity","GO:0030097///hemopoiesis+++GO:0033489///cholesterol biosynthetic process via desmosterol+++GO:0033490///cholesterol biosynthetic process via lathosterol+++GO:0001501///skeletal system development+++GO:0008203///cholesterol metabolic process+++GO:0006695///cholesterol biosynthetic process","IPR007905///Emopamil-binding protein+++IPR033118///EXPERA domain","[EBP_HUMAN|Reviewed]RecName: Full=3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase; EC=5.3.3.5 {ECO:0000269|PubMed:12760743, ECO:0000269|PubMed:8798407, ECO:0000269|PubMed:9894009}; AltName: Full=Cholestenol Delta-isomerase; AltName: Full=Delta(8)-Delta(7) sterol isomerase; Short=D8-D7 sterol isomerase; AltName: Full=Emopamil-binding protein;+++[A0A024QYX0_HUMAN|Unreviewed]SubName: Full=Emopamil binding protein {ECO:0000313|EMBL:AIL31429.1}; SubName: Full=Emopamil binding protein (Sterol isomerase), isoform CRA_a {ECO:0000313|EMBL:EAW50775.1};"]
[106821730,"'BUB1B-PAK6'",8,4,6,"04360///Axon guidance+++04012///ErbB signaling pathway+++04014///Ras signaling pathway+++04510///Focal adhesion+++04660///T cell receptor signaling pathway+++04810///Regulation of actin cytoskeleton+++05211///Renal cell carcinoma",{"$nulls":3},"GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0030054///cell junction","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0045296///cadherin binding+++GO:0048365///Rac GTPase binding","GO:0007094///mitotic spindle assembly checkpoint","IPR000095///CRIB domain+++IPR035066///Serine/threonine-protein kinase PAK 6+++IPR036936///CRIB domain superfamily+++IPR033923///p21 activated kinase binding domain+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily","[PAK6_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 6; EC=2.7.11.1; AltName: Full=PAK-5; AltName: Full=p21-activated kinase 6; Short=PAK-6;+++[A0A024R9Q4_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};+++[A0A0U1RQB7_HUMAN|Unreviewed]SubName: Full=BUB1B-PAK6 readthrough {ECO:0000313|Ensembl:ENSP00000401153};+++[H3BSN5_HUMAN|Unreviewed]SubName: Full=BUB1B-PAK6 readthrough {ECO:0000313|Ensembl:ENSP00000456785}; Flags: Fragment;+++[H3BTB9_HUMAN|Unreviewed]SubName: Full=BUB1B-PAK6 readthrough {ECO:0000313|Ensembl:ENSP00000457109}; Flags: Fragment;"]
[10683,"'DLL3'",39,38,38.5,"01522///Endocrine resistance+++05224///Breast cancer+++05200///Pathways in cancer+++04658///Th1 and Th2 cell differentiation+++04330///Notch signaling pathway","H01413///Adams-Oliver syndrome (AOS)+++H00517///Spondylocostal dysostosis (SCD)","M00682///Notch signaling",null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005112///Notch binding+++GO:0005509///calcium ion binding","GO:0001756///somitogenesis+++GO:0007275///multicellular organism development+++GO:0048339///paraxial mesoderm development+++GO:0009888///tissue development+++GO:0050768///negative regulation of neurogenesis+++GO:0007386///compartment pattern specification+++GO:0001501///skeletal system development+++GO:0007219///Notch signaling pathway+++GO:0030154///cell differentiation","IPR013032///EGF-like, conserved site+++IPR001881///EGF-like calcium-binding domain+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR000742///EGF-like domain","[DLL3_HUMAN|Reviewed]RecName: Full=Delta-like protein 3; AltName: Full=Drosophila Delta homolog 3; Short=Delta3; Flags: Precursor;+++[M0R177_HUMAN|Unreviewed]SubName: Full=Delta-like protein 3 {ECO:0000313|Ensembl:ENSP00000471688}; Flags: Fragment;"]
[10686,"'CLDN16'",4.97,9,6.985,"04530///Tight junction+++04670///Leukocyte transendothelial migration+++04514///Cell adhesion molecules (CAMs)+++05160///Hepatitis C","H01210///Hypomagnesemia+++H00605///Deafness, autosomal recessive+++H01439///Williams-Beuren syndrome+++H00742///Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0005923///bicellular tight junction","GO:0005198///structural molecule activity+++GO:0042802///identical protein binding+++GO:0015095///magnesium ion transmembrane transporter activity+++GO:0005515///protein binding","GO:0006875///cellular metal ion homeostasis+++GO:0006811///ion transport+++GO:0007588///excretion+++GO:0016338///calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules+++GO:1903830///magnesium ion transmembrane transport","IPR004031///PMP-22/EMP/MP20/Claudin superfamily+++IPR003927///Claudin-16+++IPR006187///Claudin+++IPR017974///Claudin, conserved site","[CLD16_HUMAN|Reviewed]RecName: Full=Claudin-16; AltName: Full=Paracellin-1; Short=PCLN-1;+++[A0SDD8_HUMAN|Unreviewed]SubName: Full=Claudin-16 {ECO:0000313|Ensembl:ENSP00000414136}; SubName: Full=PCLN-1 {ECO:0000313|EMBL:ABC47832.1};"]
[106865373,"'WRB-SH3BGR'",7.38,9.87,8.625,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane","GO:0017124///SH3 domain binding+++GO:0005070///SH3/SH2 adaptor activity","GO:0065003///protein-containing complex assembly+++GO:0071816///tail-anchored membrane protein insertion into ER membrane","IPR028945///WRB/Get1 family+++IPR039012///Tail-anchored protein insertion receptor WRB+++IPR036249///Thioredoxin-like superfamily+++IPR006993///SH3-binding, glutamic acid-rich protein","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[MOST1_HUMAN|diamond]RecName: Full=Protein MOST-1;+++[SH3BG_HUMAN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich protein; Short=SH3BGR protein; AltName: Full=21-glutamic acid-rich protein; Short=21-GARP;+++[SH3BG_MOUSE|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich protein; Short=SH3BGR protein;+++[SH3L1_BOVIN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_HUMAN|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_MACFA|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[SH3L1_PONAB|diamond]RecName: Full=SH3 domain-binding glutamic acid-rich-like protein;+++[WRB_BOVIN|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[WRB_HUMAN|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Congenital heart disease 5 protein; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[WRB_PONAB|diamond]RecName: Full=Tail-anchored protein insertion receptor WRB; AltName: Full=Tryptophan-rich basic protein; Short=WRB;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN701_HUMAN|diamond]RecName: Full=Zinc finger protein 701;"]
[10687,"'PNMA2'",195,257.23,226.115,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0043065///positive regulation of apoptotic process","IPR026525///Paraneoplastic antigen Ma2+++IPR026523///Paraneoplastic antigen Ma","[PNMA2_HUMAN|Reviewed]RecName: Full=Paraneoplastic antigen Ma2; AltName: Full=40 kDa neuronal protein; AltName: Full=Onconeuronal antigen Ma2; AltName: Full=Paraneoplastic neuronal antigen MM2;+++[Q5U5Z3_HUMAN|Unreviewed]SubName: Full=Paraneoplastic antigen MA2 {ECO:0000313|EMBL:AAH36489.1};"]
[1069,"'CETN2'",750,648,699,"03420///Nucleotide excision repair",{"$nulls":3},"GO:0005813///centrosome+++GO:0005654///nucleoplasm+++GO:0005814///centriole+++GO:0036064///ciliary basal body+++GO:0032391///photoreceptor connecting cilium+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005622///intracellular+++GO:0005929///cilium+++GO:0071942///XPC complex+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0032795///heterotrimeric G-protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0005515///protein binding","GO:0007099///centriole replication+++GO:0019722///calcium-mediated signaling+++GO:0006289///nucleotide-excision repair+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0007283///spermatogenesis+++GO:0010824///regulation of centrosome duplication+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0070911///global genome nucleotide-excision repair+++GO:0000278///mitotic cell cycle+++GO:0032465///regulation of cytokinesis+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0006281///DNA repair+++GO:0000281///mitotic cytokinesis","IPR002048///EF-hand domain+++IPR000629///ATP-dependent RNA helicase DEAD-box, conserved site+++IPR011992///EF-hand domain pair+++IPR018247///EF-Hand 1, calcium-binding site","[CETN2_HUMAN|Reviewed]RecName: Full=Centrin-2; AltName: Full=Caltractin isoform 1;"]
[10690,"'FUT9'",3,0,1.5,"00515///Mannose type O-glycan biosynthesis+++01100///Metabolic pathways+++00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++00603///Glycosphingolipid biosynthesis - globo and isoglobo series",null,null,"R05904///GDP-L-fucose + G00103 <=> GDP + G00104+++R06227///GDP-L-fucose + G00081 <=> GDP + G00082+++R06025///GDP-L-fucose + Paragloboside <=> GDP + III3Fuc-nLc4Cer+++R06039///GDP-L-fucose + nLc8Cer <=> GDP + G00084+++R06222///GDP-L-fucose + G00084 <=> GDP + G00085+++R06076///GDP-L-fucose + VI2Fuc-nLc6 <=> GDP + G00081+++R06095///GDP-L-fucose + IV2Fuc-nLc4Cer <=> GDP + III3,IV2Fuc-nLc4Cer+++R06224///GDP-L-fucose + G00085 <=> GDP + G00086+++R06230///GDP-L-fucose + nLc6Cer <=> GDP + III3Fuc-nLc6Cer+++R06221///GDP-L-fucose + V3Fuc-nLc6Cer <=> GDP + V3Fuc,III3Fuc-nLc6Cer+++R06038///GDP-L-fucose + nLc6Cer <=> GDP + V3Fuc-nLc6Cer","GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane+++GO:0016021///integral component of membrane","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008417///fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0046920///alpha-(1->3)-fucosyltransferase activity","GO:0007399///nervous system development+++GO:0036065///fucosylation+++GO:0006486///protein glycosylation+++GO:0005975///carbohydrate metabolic process+++GO:0042355///L-fucose catabolic process","IPR031481///Fucosyltransferase, N-terminal+++IPR001503///Glycosyl transferase family 10+++IPR038577///GT10-like superfamily","[FUT9_HUMAN|Reviewed]RecName: Full=Alpha-(1,3)-fucosyltransferase 9; EC=2.4.1.-; AltName: Full=Fucosyltransferase 9; AltName: Full=Fucosyltransferase IX; Short=Fuc-TIX; Short=FucT-IX; AltName: Full=Galactoside 3-L-fucosyltransferase;+++[B4DEW1_HUMAN|Unreviewed]SubName: Full=Alternative protein FUT9 {ECO:0000313|EMBL:CCQ43364.1}; SubName: Full=cDNA FLJ52603 {ECO:0000313|EMBL:BAG57222.1};+++[Q5Q0U2_HUMAN|Unreviewed]SubName: Full=Fucosyltransferase 9 (Alpha (1,3) fucosyltransferase), isoform CRA_a {ECO:0000313|EMBL:EAW48510.1}; SubName: Full=cDNA, FLJ95882, Homo sapiens fucosyltransferase 9 (alpha (1,3) fucosyltransferase) (FUT9), mRNA {ECO:0000313|EMBL:BAG37467.1};"]
[10691,"'GMEB1'",120,128.56,124.28,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0003713///transcription coactivator activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR000770///SAND domain+++IPR024830///Glucocorticoid modulatory element-binding protein 1/2+++IPR010919///SAND-like domain superfamily","[GMEB1_HUMAN|Reviewed]RecName: Full=Glucocorticoid modulatory element-binding protein 1; Short=GMEB-1; AltName: Full=DNA-binding protein p96PIF; AltName: Full=Parvovirus initiation factor p96; Short=PIF p96;+++[B1AT47_HUMAN|Unreviewed]SubName: Full=Glucocorticoid modulatory element binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAX07679.1}; SubName: Full=cDNA, FLJ96492, Homo sapiens glucocorticoid modulatory element binding protein 1(GMEB1), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG37824.1};+++[B2RCN8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ96179, highly similar to Homo sapiens glucocorticoid modulatory element binding protein 1 (GMEB1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG37635.1};"]
[10693,"'CCT6B'",13,10,11.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005832///chaperonin-containing T-complex","GO:0008565///protein transporter activity+++GO:0051082///unfolded protein binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006457///protein folding+++GO:0007283///spermatogenesis+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0015031///protein transport+++GO:1901998///toxin transport","IPR017998///Chaperone tailless complex polypeptide 1 (TCP-1)+++IPR027413///GroEL-like equatorial domain superfamily+++IPR002194///Chaperonin TCP-1, conserved site+++IPR012722///T-complex protein 1, zeta subunit+++IPR002423///Chaperonin Cpn60/TCP-1 family+++IPR027409///GroEL-like apical domain superfamily+++IPR027410///TCP-1-like chaperonin intermediate domain superfamily","[TCPW_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit zeta-2; Short=TCP-1-zeta-2; AltName: Full=CCT-zeta-2; AltName: Full=CCT-zeta-like; AltName: Full=TCP-1-zeta-like; AltName: Full=Testis-specific Tcp20; AltName: Full=Testis-specific protein TSA303 {ECO:0000303|PubMed:8812458};+++[J3KRI6_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit zeta-2 {ECO:0000313|Ensembl:ENSP00000462020}; Flags: Fragment;"]
[10694,"'CCT8'",1225,1094,1159.5,{"$nulls":4},"GO:0005832///chaperonin-containing T-complex+++GO:0005737///cytoplasm+++GO:0034774///secretory granule lumen+++GO:0042995///cell projection+++GO:0005929///cilium+++GO:0002199///zona pellucida receptor complex+++GO:0070062///extracellular exosome+++GO:0035578///azurophil granule lumen+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005815///microtubule organizing center+++GO:0005576///extracellular region+++GO:0044297///cell body+++GO:0005856///cytoskeleton+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005874///microtubule","GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0051082///unfolded protein binding+++GO:0042623///ATPase activity, coupled+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:1904874///positive regulation of telomerase RNA localization to Cajal body+++GO:1904851///positive regulation of establishment of protein localization to telomere+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0007339///binding of sperm to zona pellucida+++GO:1904871///positive regulation of protein localization to Cajal body+++GO:0006457///protein folding+++GO:0050821///protein stabilization+++GO:0043312///neutrophil degranulation+++GO:1901998///toxin transport+++GO:0046931///pore complex assembly","IPR002194///Chaperonin TCP-1, conserved site+++IPR012721///T-complex protein 1, theta subunit+++IPR027413///GroEL-like equatorial domain superfamily+++IPR027410///TCP-1-like chaperonin intermediate domain superfamily+++IPR027409///GroEL-like apical domain superfamily+++IPR017998///Chaperone tailless complex polypeptide 1 (TCP-1)+++IPR002423///Chaperonin Cpn60/TCP-1 family","[TCPQ_HUMAN|Reviewed]RecName: Full=T-complex protein 1 subunit theta; Short=TCP-1-theta; AltName: Full=CCT-theta; AltName: Full=Chaperonin containing T-complex polypeptide 1 subunit 8; AltName: Full=Renal carcinoma antigen NY-REN-15;+++[H7C2U0_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit theta {ECO:0000313|Ensembl:ENSP00000407748}; Flags: Fragment;+++[H7C4C8_HUMAN|Unreviewed]SubName: Full=T-complex protein 1 subunit theta {ECO:0000313|Ensembl:ENSP00000416832}; Flags: Fragment;+++[Q7Z759_HUMAN|Unreviewed]SubName: Full=CCT8 protein {ECO:0000313|EMBL:AAH12584.1}; SubName: Full=Chaperonin containing TCP1, subunit 8 (Theta), isoform CRA_c {ECO:0000313|EMBL:EAX09926.1};"]
[10695,"'CNPY3'",984,643,813.5,"00260///Glycine, serine and threonine metabolism","H00184///Hypermethioninemia",null,"R00367///S-Adenosyl-L-methionine:glycine N-methyltransferase S-Adenosyl-L-methionine + Glycine <=> S-Adenosyl-L-homocysteine + Sarcosine","GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen","GO:0005102///signaling receptor binding","GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0002224///toll-like receptor signaling pathway","IPR021852///Domain of unknown function DUF3456","[CNPY3_HUMAN|Reviewed]RecName: Full=Protein canopy homolog 3; AltName: Full=CTG repeat protein 4a; AltName: Full=Expanded repeat-domain protein CAG/CTG 5; AltName: Full=Protein associated with TLR4; AltName: Full=Trinucleotide repeat-containing gene 5 protein; Flags: Precursor;+++[A0A024RCZ2_HUMAN|Unreviewed]SubName: Full=Trinucleotide repeat containing 5, isoform CRA_g {ECO:0000313|EMBL:EAX04118.1};+++[A0A024RD07_HUMAN|Unreviewed]SubName: Full=Trinucleotide repeat containing 5, isoform CRA_c {ECO:0000313|EMBL:EAX04122.1};+++[A0A0C4DFY8_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 3 {ECO:0000313|Ensembl:ENSP00000377698};"]
[10699,"'CORIN'",0,6,3,null,"H00624///Familial cholestasis",null,null,"GO:0009986///cell surface+++GO:0016604///nuclear body+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0015629///actin cytoskeleton+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0008236///serine-type peptidase activity+++GO:0016787///hydrolase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity","GO:1903779///regulation of cardiac conduction+++GO:0008217///regulation of blood pressure+++GO:0003050///regulation of systemic arterial blood pressure by atrial natriuretic peptide+++GO:0016486///peptide hormone processing+++GO:0035813///regulation of renal sodium excretion+++GO:0007565///female pregnancy+++GO:0006508///proteolysis","IPR023415///Low-density lipoprotein (LDL) receptor class A, conserved site+++IPR009003///Peptidase S1, PA clan+++IPR036772///SRCR-like domain superfamily+++IPR020067///Frizzled domain+++IPR036055///LDL receptor-like superfamily+++IPR017052///Atrial natriuretic peptide-converting enzyme corin+++IPR017448///SRCR-like domain+++IPR036790///Frizzled cysteine-rich domain superfamily+++IPR033116///Serine proteases, trypsin family, serine active site+++IPR001254///Serine proteases, trypsin domain+++IPR002172///Low-density lipoprotein (LDL) receptor class A repeat","[CORIN_HUMAN|Reviewed]RecName: Full=Atrial natriuretic peptide-converting enzyme; EC=3.4.21.-; AltName: Full=Corin; AltName: Full=Heart-specific serine proteinase ATC2; AltName: Full=Pro-ANP-converting enzyme; AltName: Full=Transmembrane protease serine 10; Contains: RecName: Full=Atrial natriuretic peptide-converting enzyme, N-terminal propeptide; Contains: RecName: Full=Atrial natriuretic peptide-converting enzyme, activated protease fragment; Contains: RecName: Full=Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment; Contains: RecName: Full=Atrial natriuretic peptide-converting enzyme, 160 kDa soluble fragment; Contains: RecName: Full=Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment;+++[A0A087X1D5_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide-converting enzyme {ECO:0000313|Ensembl:ENSP00000484087};+++[B4E1Y7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50947, highly similar to Atrial natriuteric peptide-converting enzyme {ECO:0000313|EMBL:BAG64949.1};+++[B4E2W9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57017, highly similar to Atrial natriuteric peptide-converting enzyme {ECO:0000313|EMBL:BAG65281.1};+++[E7EQE7_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide-converting enzyme {ECO:0000313|Ensembl:ENSP00000425597};+++[J3KR83_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide-converting enzyme {ECO:0000313|Ensembl:ENSP00000423216};+++[J3KR88_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide-converting enzyme {ECO:0000313|Ensembl:ENSP00000424212};+++[J3KR90_HUMAN|Unreviewed]SubName: Full=Atrial natriuretic peptide-converting enzyme {ECO:0000313|Ensembl:ENSP00000425401};"]
[107,"'ADCY1'",199,223,211,"04926///Relaxin signaling pathway+++04714///Thermogenesis+++04916///Melanogenesis+++04611///Platelet activation+++04971///Gastric acid secretion+++05032///Morphine addiction+++04727///GABAergic synapse+++04724///Glutamatergic synapse+++04720///Long-term potentiation+++04970///Salivary secretion+++05142///Chagas disease (American trypanosomiasis)+++04270///Vascular smooth muscle contraction+++04927///Cortisol synthesis and secretion+++04934///Cushing's syndrome+++04921///Oxytocin signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04750///Inflammatory mediator regulation of TRP channels+++04713///Circadian entrainment+++04020///Calcium signaling pathway+++00230///Purine metabolism+++04015///Rap1 signaling pathway+++05146///Amoebiasis+++04913///Ovarian steroidogenesis+++04072///Phospholipase D signaling pathway+++04371///Apelin signaling pathway+++04723///Retrograde endocannabinoid signaling+++04213///Longevity regulating pathway - multiple species+++04022///cGMP-PKG signaling pathway+++04725///Cholinergic synapse+++04925///Aldosterone synthesis and secretion+++01522///Endocrine resistance+++04211///Longevity regulating pathway+++04972///Pancreatic secretion+++05200///Pathways in cancer+++04928///Parathyroid hormone synthesis, secretion and action+++04114///Oocyte meiosis+++04918///Thyroid hormone synthesis+++04024///cAMP signaling pathway+++04911///Insulin secretion+++05163///Human cytomegalovirus infection+++04912///GnRH signaling pathway+++04062///Chemokine signaling pathway+++04915///Estrogen signaling pathway+++05166///HTLV-I infection+++05414///Dilated cardiomyopathy (DCM)+++04540///Gap junction+++04914///Progesterone-mediated oocyte maturation+++04976///Bile secretion+++04923///Regulation of lipolysis in adipocytes",null,"M00695///cAMP signaling","R00434///GTP diphosphate-lyase (cyclizing; 3',5'-cyclic-GMP-forming)   GTP <=> 3',5'-Cyclic GMP + Diphosphate+++R00089///ATP diphosphate-lyase (cyclizing; 3',5'-cyclic-AMP-forming)   ATP <=> 3',5'-Cyclic AMP + Diphosphate","GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0070062///extracellular exosome+++GO:0045121///membrane raft+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0005737///cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0014069///postsynaptic density+++GO:0005634///nucleus","GO:0008294///calcium- and calmodulin-responsive adenylate cyclase activity+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0016849///phosphorus-oxygen lyase activity+++GO:0000166///nucleotide binding+++GO:0016829///lyase activity+++GO:0004016///adenylate cyclase activity+++GO:0005516///calmodulin binding","GO:0019933///cAMP-mediated signaling+++GO:0007409///axonogenesis+++GO:0007420///brain development+++GO:0007616///long-term memory+++GO:0003091///renal water homeostasis+++GO:0042752///regulation of circadian rhythm+++GO:0071277///cellular response to calcium ion+++GO:0009190///cyclic nucleotide biosynthetic process+++GO:0050804///modulation of chemical synaptic transmission+++GO:1904322///cellular response to forskolin+++GO:0010226///response to lithium ion+++GO:0032793///positive regulation of CREB transcription factor activity+++GO:1900273///positive regulation of long-term synaptic potentiation+++GO:0150076///neuroinflammatory response+++GO:0006171///cAMP biosynthetic process+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0042493///response to drug+++GO:0071377///cellular response to glucagon stimulus+++GO:0007623///circadian rhythm+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0035556///intracellular signal transduction+++GO:0048511///rhythmic process","IPR030672///Adenylate cyclase+++IPR001054///Adenylyl cyclase class-3/4/guanylyl cyclase+++IPR029787///Nucleotide cyclase+++IPR018297///Adenylyl cyclase class-4/guanylyl cyclase, conserved site+++IPR032628///Adenylate cyclase, N-terminal","[ADCY1_HUMAN|Reviewed]RecName: Full=Adenylate cyclase type 1; EC=4.6.1.1 {ECO:0000250|UniProtKB:P19754}; AltName: Full=ATP pyrophosphate-lyase 1; AltName: Full=Adenylate cyclase type I; AltName: Full=Adenylyl cyclase 1; AltName: Full=Ca(2+)/calmodulin-activated adenylyl cyclase;+++[C9J1J0_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase 1 (Brain), isoform CRA_e {ECO:0000313|EMBL:EAW61047.1}; SubName: Full=Adenylate cyclase type 1 {ECO:0000313|Ensembl:ENSP00000392721};+++[D3DVL8_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase 1 (Brain), isoform CRA_b {ECO:0000313|EMBL:EAW61045.1};+++[L0R809_HUMAN|Unreviewed]SubName: Full=Alternative protein ADCY1 {ECO:0000313|EMBL:CCO13671.1};+++[Q8NFM5_HUMAN|Unreviewed]SubName: Full=Adenylate cyclase type I {ECO:0000313|EMBL:AAM94372.1}; EC=4.6.1.1 {ECO:0000313|EMBL:AAM94372.1}; Flags: Fragment;"]
[1070,"'CETN3'",48,57,52.5,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005815///microtubule organizing center+++GO:0000111///nucleotide-excision repair factor 2 complex+++GO:0005737///cytoplasm+++GO:0070390///transcription export complex 2+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0032391///photoreceptor connecting cilium+++GO:0036064///ciliary basal body+++GO:0005634///nucleus+++GO:0005814///centriole+++GO:0035869///ciliary transition zone+++GO:0005825///half bridge of spindle pole body","GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0008017///microtubule binding+++GO:0046872///metal ion binding","GO:0007098///centrosome cycle+++GO:1903087///mitotic spindle pole body duplication+++GO:0019722///calcium-mediated signaling+++GO:0030474///spindle pole body duplication+++GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007020///microtubule nucleation","IPR002048///EF-hand domain+++IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair","[CETN3_HUMAN|Reviewed]RecName: Full=Centrin-3;+++[E5RFM2_HUMAN|Unreviewed]SubName: Full=Centrin-3 {ECO:0000313|Ensembl:ENSP00000430361};+++[E5RH67_HUMAN|Unreviewed]SubName: Full=Centrin-3 {ECO:0000313|Ensembl:ENSP00000429875};+++[E5RJF8_HUMAN|Unreviewed]SubName: Full=Centrin-3 {ECO:0000313|Ensembl:ENSP00000428259};+++[E5RK82_HUMAN|Unreviewed]SubName: Full=Centrin-3 {ECO:0000313|Ensembl:ENSP00000430409};+++[H0YBL5_HUMAN|Unreviewed]SubName: Full=Centrin-3 {ECO:0000313|Ensembl:ENSP00000429772}; Flags: Fragment;+++[Q6ICP7_HUMAN|Unreviewed]SubName: Full=CETN3 protein {ECO:0000313|EMBL:CAG29342.1}; Flags: Fragment;"]
[10712,"'FAM189B'",2778,2762,2770,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0050699///WW domain binding+++GO:0005515///protein binding","GO:0008150///biological_process","IPR007237///CD20-like family+++IPR030431///FAM189","[F189B_HUMAN|Reviewed]RecName: Full=Protein FAM189B; AltName: Full=Protein COTE1;+++[D6RD59_HUMAN|Unreviewed]SubName: Full=Protein FAM189B {ECO:0000313|Ensembl:ENSP00000427011}; Flags: Fragment;+++[Q96AD8_HUMAN|Unreviewed]SubName: Full=C1orf2 protein {ECO:0000313|EMBL:AAH17262.1}; SubName: Full=Chromosome 1 open reading frame 2, isoform CRA_b {ECO:0000313|EMBL:EAW53095.1}; SubName: Full=Protein FAM189B {ECO:0000313|Ensembl:ENSP00000427520};+++[Q96H71_HUMAN|Unreviewed]SubName: Full=C1orf2 protein {ECO:0000313|EMBL:AAH08854.1}; SubName: Full=Protein FAM189B {ECO:0000313|Ensembl:ENSP00000479033};+++[Q9Y6J7_HUMAN|Unreviewed]SubName: Full=Cote1 {ECO:0000313|EMBL:AAC28638.1}; Flags: Fragment;"]
[10713,"'USP39'",482,430,456,"03040///Spliceosome",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0005634///nucleus+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005681///spliceosomal complex+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity","GO:0007049///cell cycle+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0000245///spliceosomal complex assembly+++GO:0051301///cell division+++GO:0016579///protein deubiquitination+++GO:0006397///mRNA processing","IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase+++IPR028889///Ubiquitin specific protease domain+++IPR001607///Zinc finger, UBP-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR033809///USP39","[SNUT2_HUMAN|Reviewed]RecName: Full=U4/U6.U5 tri-snRNP-associated protein 2; AltName: Full=Inactive ubiquitin-specific peptidase 39 {ECO:0000303|PubMed:18728397}; AltName: Full=SAD1 homolog {ECO:0000303|PubMed:11350945}; AltName: Full=U4/U6.U5 tri-snRNP-associated 65 kDa protein {ECO:0000303|PubMed:11350945}; Short=65K {ECO:0000303|PubMed:11350945};+++[A0A087WW31_HUMAN|Unreviewed]SubName: Full=U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|Ensembl:ENSP00000479885}; Flags: Fragment;+++[A0A087X1B2_HUMAN|Unreviewed]SubName: Full=U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|Ensembl:ENSP00000484024};+++[B3KMG1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10910 fis, clone OVARC1000139, highly similar to U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|EMBL:BAG50973.1};+++[B3KPG7_HUMAN|Unreviewed]SubName: Full=Ubiquitin specific peptidase 39, isoform CRA_b {ECO:0000313|EMBL:EAW99491.1}; SubName: Full=cDNA FLJ31772 fis, clone NT2RI2008007, highly similar to U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|EMBL:BAG51679.1};+++[B7Z7L9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56173, highly similar to U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|EMBL:BAH13655.1};+++[B9A018_HUMAN|Unreviewed]SubName: Full=U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|Ensembl:ENSP00000386572};+++[C9J0X5_HUMAN|Unreviewed]SubName: Full=U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|Ensembl:ENSP00000392911}; Flags: Fragment;+++[C9JIU2_HUMAN|Unreviewed]SubName: Full=U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|Ensembl:ENSP00000396854}; Flags: Fragment;+++[F8WC91_HUMAN|Unreviewed]SubName: Full=U4/U6.U5 tri-snRNP-associated protein 2 {ECO:0000313|Ensembl:ENSP00000400690};"]
[10714,"'POLD3'",91,82,86.5,"05166///HTLV-I infection+++03430///Mismatch repair+++00240///Pyrimidine metabolism+++03410///Base excision repair+++03030///DNA replication+++01100///Metabolic pathways+++03440///Homologous recombination+++03420///Nucleotide excision repair+++00230///Purine metabolism",null,"M00262///DNA polymerase delta complex","R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dTTP + DNA <=> Diphosphate + DNA+++R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dGTP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dCTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dATP + DNA <=> Diphosphate + DNA","GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0043625///delta DNA polymerase complex","GO:0005515///protein binding+++GO:0003887///DNA-directed DNA polymerase activity","GO:0019985///translesion synthesis+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0006298///mismatch repair+++GO:0000723///telomere maintenance+++GO:0006260///DNA replication+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0032201///telomere maintenance via semi-conservative replication+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006281///DNA repair","IPR019038///DNA polymerase subunit Cdc27","[DPOD3_HUMAN|Reviewed]RecName: Full=DNA polymerase delta subunit 3; AltName: Full=DNA polymerase delta subunit C {ECO:0000303|PubMed:11595739}; AltName: Full=DNA polymerase delta subunit p66; AltName: Full=DNA polymerase delta subunit p68 {ECO:0000303|PubMed:22148433, ECO:0000303|PubMed:22801543};+++[A0A024R5M8_HUMAN|Unreviewed]SubName: Full=Polymerase (DNA-directed), delta 3, accessory subunit, isoform CRA_a {ECO:0000313|EMBL:EAW74943.1};+++[E9PM91_HUMAN|Unreviewed]SubName: Full=DNA polymerase delta subunit 3 {ECO:0000313|Ensembl:ENSP00000431239}; Flags: Fragment;+++[E9PNC0_HUMAN|Unreviewed]SubName: Full=DNA polymerase delta subunit 3 {ECO:0000313|Ensembl:ENSP00000437231}; Flags: Fragment;+++[E9PRK3_HUMAN|Unreviewed]SubName: Full=DNA polymerase delta subunit 3 {ECO:0000313|Ensembl:ENSP00000432233}; Flags: Fragment;+++[H0YD46_HUMAN|Unreviewed]SubName: Full=DNA polymerase delta subunit 3 {ECO:0000313|Ensembl:ENSP00000432969}; Flags: Fragment;+++[H0YEX7_HUMAN|Unreviewed]SubName: Full=DNA polymerase delta subunit 3 {ECO:0000313|Ensembl:ENSP00000436781}; Flags: Fragment;+++[Q05BV7_HUMAN|Unreviewed]SubName: Full=POLD3 protein {ECO:0000313|EMBL:AAH32636.1}; Flags: Fragment;+++[Q569I8_HUMAN|Unreviewed]SubName: Full=POLD3 protein {ECO:0000313|EMBL:AAH92454.1}; Flags: Fragment;+++[Q8WUF6_HUMAN|Unreviewed]SubName: Full=POLD3 protein {ECO:0000313|EMBL:AAH20587.1}; Flags: Fragment;"]
[10715,"'CERS1'",344.13,275.57,309.85,"04071///Sphingolipid signaling pathway+++01100///Metabolic pathways+++00600///Sphingolipid metabolism","H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H00734///Autosomal recessive congenital ichthyosis","M00094///Ceramide biosynthesis+++M00099///Sphingosine biosynthesis","R01496///acyl-CoA:sphingosine N-acyltransferase   Acyl-CoA + Sphingosine <=> CoA + N-Acylsphingosine+++R06517///acyl-CoA:sphingosine N-acyltransferase   Acyl-CoA + Sphinganine <=> CoA + Dihydroceramide","GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0000139///Golgi membrane","GO:0008083///growth factor activity+++GO:0003674///molecular_function+++GO:0050291///sphingosine N-acyltransferase activity","GO:0046513///ceramide biosynthetic process+++GO:0035690///cellular response to drug+++GO:0072721///cellular response to dithiothreitol+++GO:0051974///negative regulation of telomerase activity+++GO:0006629///lipid metabolic process+++GO:0010469///regulation of signaling receptor activity+++GO:0036146///cellular response to mycotoxin+++GO:0030148///sphingolipid biosynthetic process+++GO:0071492///cellular response to UV-A","IPR029034///Cystine-knot cytokine+++IPR017948///Transforming growth factor beta, conserved site+++IPR015615///Transforming growth factor-beta-related+++IPR016439///Sphingosine N-acyltransferase Lag1/Lac1-like+++IPR006634///TRAM/LAG1/CLN8 homology domain+++IPR001839///Transforming growth factor-beta, C-terminal","[CERS1_HUMAN|Reviewed]RecName: Full=Ceramide synthase 1; Short=CerS1; AltName: Full=LAG1 longevity assurance homolog 1; AltName: Full=Longevity assurance gene 1 protein homolog 1; AltName: Full=Protein UOG-1;+++[B4DE47_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56956, highly similar to LAG1 longevity assurance homolog 1 {ECO:0000313|EMBL:BAG56958.1};+++[M0R0T2_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 1 {ECO:0000313|Ensembl:ENSP00000471428}; Flags: Fragment;+++[Q5XG75_HUMAN|Unreviewed]SubName: Full=Ceramide synthase 1 {ECO:0000313|Ensembl:ENSP00000437648}; SubName: Full=LASS1 protein {ECO:0000313|EMBL:AAH84582.1};"]
[10716,"'TBR1'",0,2,1,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0010092///specification of animal organ identity+++GO:0010468///regulation of gene expression+++GO:0007420///brain development+++GO:0021987///cerebral cortex development+++GO:0021764///amygdala development+++GO:0021902///commitment of neuronal cell to specific neuron type in forebrain+++GO:0001661///conditioned taste aversion+++GO:1902667///regulation of axon guidance+++GO:0030902///hindbrain development+++GO:0030182///neuron differentiation+++GO:0010975///regulation of neuron projection development+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR008967///p53-like transcription factor, DNA-binding+++IPR036960///T-box superfamily+++IPR001699///Transcription factor, T-box+++IPR018186///Transcription factor, T-box, conserved site+++IPR032385///T-box transcription factor-associated","[TBR1_HUMAN|Reviewed]RecName: Full=T-box brain protein 1; Short=T-brain-1; Short=TBR-1; AltName: Full=TES-56;+++[H7C0B1_HUMAN|Unreviewed]SubName: Full=T-box brain protein 1 {ECO:0000313|Ensembl:ENSP00000393934}; Flags: Fragment;"]
[10717,"'AP4B1'",87,107,97,"04142///Lysosome","H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0030117///membrane coat+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0031904///endosome lumen+++GO:0032588///trans-Golgi network membrane+++GO:0019898///extrinsic component of membrane+++GO:0030131///clathrin adaptor complex+++GO:0030124///AP-4 adaptor complex","GO:0030276///clathrin binding+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0006605///protein targeting+++GO:0006886///intracellular protein transport+++GO:0008104///protein localization+++GO:0016192///vesicle-mediated transport","IPR011989///Armadillo-like helical+++IPR026739///AP complex subunit beta+++IPR012295///TBP domain superfamily+++IPR002553///Clathrin/coatomer adaptor, adaptin-like, N-terminal+++IPR016024///Armadillo-type fold+++IPR015151///Beta-adaptin appendage, C-terminal subdomain+++IPR016342///AP-1/2/4 complex subunit beta","[AP4B1_HUMAN|Reviewed]RecName: Full=AP-4 complex subunit beta-1 {ECO:0000305}; AltName: Full=AP-4 adaptor complex subunit beta; AltName: Full=Adaptor-related protein complex 4 subunit beta-1; AltName: Full=Beta subunit of AP-4; AltName: Full=Beta4-adaptin;+++[A0A024R0D2_HUMAN|Unreviewed]RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};+++[B1ALD0_HUMAN|Unreviewed]RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};+++[B1ALD1_HUMAN|Unreviewed]SubName: Full=AP-4 complex subunit beta-1 {ECO:0000313|Ensembl:ENSP00000358577}; Flags: Fragment;+++[B1ALD2_HUMAN|Unreviewed]SubName: Full=AP-4 complex subunit beta-1 {ECO:0000313|Ensembl:ENSP00000358584}; Flags: Fragment;+++[B1ALD3_HUMAN|Unreviewed]SubName: Full=AP-4 complex subunit beta-1 {ECO:0000313|Ensembl:ENSP00000393622}; Flags: Fragment;+++[B3KSJ4_HUMAN|Unreviewed]RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};+++[B4DTG3_HUMAN|Unreviewed]RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};"]
[10718,"'NRG3'",100,117,108.5,"04012///ErbB signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0008083///growth factor activity+++GO:0030297///transmembrane receptor protein tyrosine kinase activator activity+++GO:0005102///signaling receptor binding+++GO:0030971///receptor tyrosine kinase binding+++GO:0045499///chemorepellent activity","GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0021842///chemorepulsion involved in interneuron migration from the subpallium to the cortex+++GO:0030879///mammary gland development+++GO:0001558///regulation of cell growth+++GO:2001223///negative regulation of neuron migration+++GO:0060596///mammary placode formation+++GO:0035556///intracellular signal transduction+++GO:0007389///pattern specification process+++GO:0007399///nervous system development+++GO:0010469///regulation of signaling receptor activity+++GO:0050804///modulation of chemical synaptic transmission","IPR002154///Neuregulin, C-terminal+++IPR013032///EGF-like, conserved site+++IPR000742///EGF-like domain","[NRG3_HUMAN|Reviewed]RecName: Full=Pro-neuregulin-3, membrane-bound isoform; Short=Pro-NRG3; Contains: RecName: Full=Neuregulin-3; Short=NRG-3; Flags: Precursor;+++[B3KVG8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16534 fis, clone OCBBF2029471, highly similar to Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|EMBL:BAG53780.1};+++[B9EGV5_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 {ECO:0000313|EMBL:AAI36812.1};+++[D9ZHP6_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 1 {ECO:0000313|EMBL:ADK90020.1};+++[D9ZHP7_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 3 {ECO:0000313|EMBL:ADK90021.1};+++[D9ZHP8_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 4 {ECO:0000313|EMBL:ADK90022.1};+++[D9ZHP9_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 5 {ECO:0000313|EMBL:ADK90023.1};+++[D9ZHQ0_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 6 {ECO:0000313|EMBL:ADK90024.1};+++[D9ZHQ1_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 7 {ECO:0000313|EMBL:ADK90025.1};+++[D9ZHQ2_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 8 {ECO:0000313|EMBL:ADK90026.1};+++[D9ZHQ3_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 10 {ECO:0000313|EMBL:ADK90028.1}; SubName: Full=Neuregulin 3 variant 9 {ECO:0000313|EMBL:ADK90027.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000451858};+++[D9ZHQ5_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 11 {ECO:0000313|EMBL:ADK90029.1};+++[D9ZHQ6_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 12 {ECO:0000313|EMBL:ADK90030.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000385804};+++[D9ZHQ7_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 13 {ECO:0000313|EMBL:ADK90031.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000451376};+++[D9ZHQ8_HUMAN|Unreviewed]SubName: Full=Neuregulin 3 variant 14 {ECO:0000313|EMBL:ADK90032.1}; SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000440377};+++[R4GNI6_HUMAN|Unreviewed]SubName: Full=Pro-neuregulin-3, membrane-bound isoform {ECO:0000313|Ensembl:ENSP00000473669};"]
[1072,"'CFL1'",36276,27606,31941,"04666///Fc gamma R-mediated phagocytosis+++04810///Regulation of actin cytoskeleton+++05133///Pertussis+++04360///Axon guidance","H00698///Nemaline myopathy",null,null,"GO:0031258///lamellipodium membrane+++GO:0032587///ruffle membrane+++GO:0016363///nuclear matrix+++GO:0030864///cortical actin cytoskeleton+++GO:0031982///vesicle+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0030027///lamellipodium+++GO:0005737///cytoplasm","GO:0051015///actin filament binding+++GO:0005102///signaling receptor binding","GO:0044794///positive regulation by host of viral process+++GO:0006468///protein phosphorylation+++GO:0043200///response to amino acid+++GO:0001842///neural fold formation+++GO:0022604///regulation of cell morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0043066///negative regulation of apoptotic process+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0007266///Rho protein signal transduction+++GO:0001755///neural crest cell migration+++GO:0030043///actin filament fragmentation+++GO:0030010///establishment of cell polarity+++GO:0030042///actin filament depolymerization+++GO:0000281///mitotic cytokinesis+++GO:0007010///cytoskeleton organization+++GO:0009615///response to virus","IPR029006///ADF-H/Gelsolin-like domain superfamily+++IPR017904///ADF/Cofilin+++IPR002108///Actin-depolymerising factor homology domain+++IPR027234///Cofilin 1","[COF1_HUMAN|Reviewed]RecName: Full=Cofilin-1; AltName: Full=18 kDa phosphoprotein; Short=p18; AltName: Full=Cofilin, non-muscle isoform;+++[V9HWI5_HUMAN|Unreviewed]SubName: Full=Cofilin 1 (Non-muscle), isoform CRA_b {ECO:0000313|EMBL:EAW74452.1}; SubName: Full=Epididymis secretory protein Li 15 {ECO:0000313|EMBL:ACJ13657.1};"]
[10721,"'POLQ'",3,2,2.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005694///chromosome+++GO:0005840///ribosome+++GO:0022625///cytosolic large ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0005654///nucleoplasm","GO:0005524///ATP binding+++GO:0003682///chromatin binding+++GO:0003684///damaged DNA binding+++GO:0003723///RNA binding+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0042802///identical protein binding+++GO:0043142///single-stranded DNA-dependent ATPase activity+++GO:0003887///DNA-directed DNA polymerase activity","GO:0097681///double-strand break repair via alternative nonhomologous end joining+++GO:0006281///DNA repair+++GO:0051260///protein homooligomerization+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006412///translation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000470///maturation of LSU-rRNA+++GO:0006284///base-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006302///double-strand break repair+++GO:2000042///negative regulation of double-strand break repair via homologous recombination+++GO:0006261///DNA-dependent DNA replication+++GO:0016446///somatic hypermutation of immunoglobulin genes","IPR001098///DNA-directed DNA polymerase, family A, palm domain+++IPR002298///DNA polymerase A+++IPR012337///Ribonuclease H-like superfamily+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR011545///DEAD/DEAH box helicase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR036397///Ribonuclease H superfamily+++IPR001650///Helicase, C-terminal+++IPR019760///DNA-directed DNA polymerase, family A, conserved site","[DPOLQ_HUMAN|Reviewed]RecName: Full=DNA polymerase theta {ECO:0000303|PubMed:10395804, ECO:0000303|PubMed:14576298, ECO:0000312|HGNC:HGNC:9186}; EC=2.7.7.7 {ECO:0000269|PubMed:14576298, ECO:0000269|PubMed:22135286}; AltName: Full=DNA polymerase eta {ECO:0000303|Ref.4};+++[Q59EE4_HUMAN|Unreviewed]SubName: Full=DNA polymerase theta variant {ECO:0000313|EMBL:BAD93104.1}; Flags: Fragment;"]
[10723,"'SLC12A7'",1324,1170,1247,"04966///Collecting duct acid secretion",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0015379///potassium:chloride symporter activity+++GO:0005215///transporter activity+++GO:0019901///protein kinase binding+++GO:0015377///cation:chloride symporter activity+++GO:0015293///symporter activity","GO:1902476///chloride transmembrane transport+++GO:0006884///cell volume homeostasis+++GO:1990573///potassium ion import across plasma membrane+++GO:0007268///chemical synaptic transmission+++GO:0055075///potassium ion homeostasis+++GO:0055064///chloride ion homeostasis+++GO:0006813///potassium ion transport+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0055085///transmembrane transport","IPR018491///SLC12A transporter, C-terminal+++IPR004842///SLC12A transporter family+++IPR000076///K/Cl co-transporter+++IPR030354///K/Cl co-transporter 4+++IPR004841///Amino acid permease/ SLC12A domain","[S12A7_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 7; AltName: Full=Electroneutral potassium-chloride cotransporter 4; AltName: Full=K-Cl cotransporter 4;+++[A0A0G2JNW7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 7 {ECO:0000313|Ensembl:ENSP00000482242};+++[A0A0G2JQE3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 7 {ECO:0000313|Ensembl:ENSP00000485792}; Flags: Fragment;+++[A0A0U1RR10_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 7 {ECO:0000313|Ensembl:ENSP00000489272}; Flags: Fragment;+++[A0A0U1RR18_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 7 {ECO:0000313|Ensembl:ENSP00000489285}; Flags: Fragment;+++[H0YB78_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 7 {ECO:0000313|Ensembl:ENSP00000428854}; Flags: Fragment;+++[L8E7W0_HUMAN|Unreviewed]SubName: Full=Alternative protein SLC12A7 {ECO:0000313|EMBL:CCQ43365.1};"]
[10724,"'OGA'",738,979,858.5,"04931///Insulin resistance",null,null,"R09673///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine N-acetylglucosaminyl hydrolase   [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine + H2O <=> [Protein]-L-threonine + N-Acetyl-D-glucosamine+++R09672///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine N-acetylglucosaminyl hydrolase   [Protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine + H2O <=> [Protein]-L-serine + N-Acetyl-D-glucosamine","GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0102167///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity+++GO:0016787///hydrolase activity+++GO:0102571///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016231///beta-N-acetylglucosaminidase activity+++GO:0004415///hyalurononglucosaminidase activity+++GO:0102166///[protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity","GO:0016032///viral process+++GO:0006517///protein deglycosylation+++GO:0006516///glycoprotein catabolic process+++GO:0008152///metabolic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0009100///glycoprotein metabolic process+++GO:0006493///protein O-linked glycosylation","IPR011496///Beta-N-acetylglucosaminidase+++IPR017853///Glycoside hydrolase superfamily+++IPR016181///Acyl-CoA N-acyltransferase","[OGA_HUMAN|Reviewed]RecName: Full=Protein O-GlcNAcase {ECO:0000303|PubMed:11148210, ECO:0000303|PubMed:11788610, ECO:0000305}; Short=OGA {ECO:0000303|PubMed:20863279}; EC=3.2.1.169 {ECO:0000269|PubMed:11148210, ECO:0000269|PubMed:11788610, ECO:0000269|PubMed:18586680, ECO:0000269|PubMed:20863279, ECO:0000269|PubMed:22365600, ECO:0000305|PubMed:20673219}; AltName: Full=Beta-N-acetylglucosaminidase {ECO:0000303|PubMed:11148210}; AltName: Full=Beta-N-acetylhexosaminidase; AltName: Full=Beta-hexosaminidase; AltName: Full=Meningioma-expressed antigen 5 {ECO:0000303|PubMed:9811929}; AltName: Full=N-acetyl-beta-D-glucosaminidase; AltName: Full=N-acetyl-beta-glucosaminidase; AltName: Full=Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; Short=NCOAT;+++[H7C3X0_HUMAN|Unreviewed]SubName: Full=Protein O-GlcNAcase {ECO:0000313|Ensembl:ENSP00000414235}; Flags: Fragment;"]
[10725,"'NFAT5'",499,956,727.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0044798///nuclear transcription factor complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:0007588///excretion+++GO:0070884///regulation of calcineurin-NFAT signaling cascade+++GO:0010628///positive regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071345///cellular response to cytokine stimulus+++GO:0001816///cytokine production+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0006366///transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:1901224///positive regulation of NIK/NF-kappaB signaling","IPR037059///Rel homology domain (RHD), DNA-binding domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR008967///p53-like transcription factor, DNA-binding+++IPR014756///Immunoglobulin E-set+++IPR015646///Nuclear factor of activated T-cells 5+++IPR011539///Rel homology domain (RHD), DNA-binding domain+++IPR032397///Rel homology dimerisation domain+++IPR008366///Nuclear factor of activated T cells (NFAT)+++IPR002909///IPT domain","[NFAT5_HUMAN|Reviewed]RecName: Full=Nuclear factor of activated T-cells 5; Short=NF-AT5; AltName: Full=T-cell transcription factor NFAT5; AltName: Full=Tonicity-responsive enhancer-binding protein {ECO:0000303|PubMed:10051678}; Short=TonE-binding protein {ECO:0000303|PubMed:10051678}; Short=TonEBP {ECO:0000303|PubMed:10051678};+++[A0A024R734_HUMAN|Unreviewed]SubName: Full=Nuclear factor of activated T-cells 5, tonicity-responsive, isoform CRA_b {ECO:0000313|EMBL:EAW83280.1};+++[F6X8W2_HUMAN|Unreviewed]SubName: Full=Nuclear factor of-activated T-cells 5 {ECO:0000313|Ensembl:ENSP00000413126};+++[H3BP21_HUMAN|Unreviewed]SubName: Full=Nuclear factor of-activated T-cells 5 {ECO:0000313|Ensembl:ENSP00000455115};+++[J3KRL6_HUMAN|Unreviewed]SubName: Full=Nuclear factor of-activated T-cells 5 {ECO:0000313|Ensembl:ENSP00000462061}; Flags: Fragment;+++[J3QKS5_HUMAN|Unreviewed]SubName: Full=Nuclear factor of-activated T-cells 5 {ECO:0000313|Ensembl:ENSP00000463214}; Flags: Fragment;"]
[10726,"'NUDC'",1902,1356,1629,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0051082///unfolded protein binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding","GO:0032502///developmental process+++GO:0051301///cell division+++GO:0007275///multicellular organism development+++GO:0008283///cell proliferation+++GO:0007049///cell cycle+++GO:0006457///protein folding","IPR008978///HSP20-like chaperone+++IPR037898///NudC family+++IPR007052///CS domain+++IPR032572///Nuclear migration protein nudC+++IPR025934///NudC N-terminal domain","[NUDC_HUMAN|Reviewed]RecName: Full=Nuclear migration protein nudC; AltName: Full=Nuclear distribution protein C homolog;+++[A0A0A0MSS4_HUMAN|Unreviewed]SubName: Full=Nuclear migration protein nudC {ECO:0000313|Ensembl:ENSP00000400981}; Flags: Fragment;+++[A0A0A0MSU9_HUMAN|Unreviewed]SubName: Full=Nuclear migration protein nudC {ECO:0000313|Ensembl:ENSP00000404020}; Flags: Fragment;+++[Q9H2R7_HUMAN|Unreviewed]SubName: Full=NPD011 {ECO:0000313|EMBL:AAG44476.1};"]
[10741,"'RBBP9'",310,390,350,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0042127///regulation of cell proliferation","IPR010662///Putative hydrolase RBBP9/YdeN+++IPR029058///Alpha/Beta hydrolase fold","[RBBP9_HUMAN|Reviewed]RecName: Full=Putative hydrolase RBBP9; EC=3.-.-.-; AltName: Full=B5T-overexpressed gene protein; Short=Protein BOG; AltName: Full=Retinoblastoma-binding protein 10; Short=RBBP-10; AltName: Full=Retinoblastoma-binding protein 9; Short=RBBP-9;"]
[10746,"'MAP3K2'",174,287,230.5,"04540///Gap junction+++04912///GnRH signaling pathway+++04010///MAPK signaling pathway",null,"M00689///MAPK (p38) signaling+++M00690///MAPK (ERK5) signaling+++M00688///MAPK (JNK) signaling",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0004672///protein kinase activity+++GO:0005515///protein binding","GO:0000165///MAPK cascade+++GO:0071260///cellular response to mechanical stimulus+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0023014///signal transduction by protein phosphorylation+++GO:0007257///activation of JUN kinase activity+++GO:0000186///activation of MAPKK activity+++GO:0000187///activation of MAPK activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0032147///activation of protein kinase activity","IPR017441///Protein kinase, ATP binding site+++IPR034879///Mitogen-activated protein kinase kinase kinase 2/3, PB1 domain+++IPR000719///Protein kinase domain+++IPR000270///PB1 domain+++IPR011009///Protein kinase-like domain superfamily","[M3K2_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase 2; EC=2.7.11.25; AltName: Full=MAPK/ERK kinase kinase 2; Short=MEK kinase 2; Short=MEKK 2;+++[A0A024RAH0_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW95316.1};+++[F8W6K3_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase kinase 2 {ECO:0000313|Ensembl:ENSP00000386313}; Flags: Fragment;+++[Q6P084_HUMAN|Unreviewed]SubName: Full=MAP3K2 protein {ECO:0000313|EMBL:AAH65755.1}; Flags: Fragment;"]
[10771,"'ZMYND11'",841,865,853,{"$nulls":4},"GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0046872///metal ion binding+++GO:0003714///transcription corepressor activity+++GO:0035064///methylated histone binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0016032///viral process+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0034243///regulation of transcription elongation from RNA polymerase II promoter+++GO:0046329///negative regulation of JNK cascade+++GO:0007049///cell cycle+++GO:0051607///defense response to virus+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0006325///chromatin organization+++GO:0008283///cell proliferation","IPR035505///ZMYND8/11, PWWP domain+++IPR001965///Zinc finger, PHD-type+++IPR002893///Zinc finger, MYND-type+++IPR036427///Bromodomain-like superfamily+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR001487///Bromodomain+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR000313///PWWP domain+++IPR019787///Zinc finger, PHD-finger","[ZMY11_HUMAN|Reviewed]RecName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000305}; AltName: Full=Adenovirus 5 E1A-binding protein; AltName: Full=Bone morphogenetic protein receptor-associated molecule 1; AltName: Full=Protein BS69;+++[A0A0A0MRY2_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000371017};+++[B0QZE2_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000385484};+++[B7Z2J6_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000309992}; SubName: Full=cDNA FLJ50504, highly similar to Mus musculus zinc finger, MYND domain containing 11 (Zmynd11), mRNA {ECO:0000313|EMBL:BAH11882.1};+++[E7ENI9_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000386010};+++[E7EV75_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000381046}; Flags: Fragment;+++[E9PE09_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000397072}; Flags: Fragment;+++[J3QKD2_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain-containing protein 11 {ECO:0000313|Ensembl:ENSP00000370996}; SubName: Full=Zinc finger, MYND domain containing 11, isoform CRA_d {ECO:0000313|EMBL:EAW86542.1};+++[Q5BJG6_HUMAN|Unreviewed]SubName: Full=ZMYND11 protein {ECO:0000313|EMBL:AAH91489.1};+++[Q5UGI2_HUMAN|Unreviewed]SubName: Full=Zinc finger MYND domain containing 11 transcript variant 3 {ECO:0000313|EMBL:AAV33128.1};+++[Q6PJR5_HUMAN|Unreviewed]SubName: Full=ZMYND11 protein {ECO:0000313|EMBL:AAH12586.1}; Flags: Fragment;"]
[10795,"'ZNF268'",132,168,150,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0008285///negative regulation of cell proliferation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0043066///negative regulation of apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043497///regulation of protein heterodimerization activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007346///regulation of mitotic cell cycle+++GO:0030335///positive regulation of cell migration+++GO:0090073///positive regulation of protein homodimerization activity+++GO:0043065///positive regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0071157///negative regulation of cell cycle arrest+++GO:0045597///positive regulation of cell differentiation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001934///positive regulation of protein phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045732///positive regulation of protein catabolic process+++GO:0030154///cell differentiation","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily+++IPR017125///PR-domain zinc finger protein PRDM5-like+++IPR001909///Krueppel-associated box","[ZN268_HUMAN|Reviewed]RecName: Full=Zinc finger protein 268; AltName: Full=Zinc finger protein HZF3;+++[A0A075B6T9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000439539};+++[A0A087WV54_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000479191};+++[E7EV44_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000409295};+++[F5H1T2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000438941};+++[F5H467_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000446153}; Flags: Fragment;+++[F5H670_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000437858};+++[F5H6R9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000437410};+++[F5H7L3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000442446};+++[F5H848_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000443721};+++[K7EIF0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000464721}; Flags: Fragment;+++[K7EMS6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000466629}; Flags: Fragment;+++[K7EQP6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 268 {ECO:0000313|Ensembl:ENSP00000467922};+++[Q2TB61_HUMAN|Unreviewed]SubName: Full=ZNF268 protein {ECO:0000313|EMBL:AAI10543.1};"]
[107984126,"'LOC107984126'",17.61,5.92,11.765,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[Z658B_HUMAN|diamond]RecName: Full=Zinc finger protein 658B;+++[ZKSC1_MOUSE|diamond]RecName: Full=Zinc finger protein with KRAB and SCAN domains 1;+++[ZN135_HUMAN|diamond]RecName: Full=Zinc finger protein 135; AltName: Full=Zinc finger protein 61; AltName: Full=Zinc finger protein 78-like 1;+++[ZN510_HUMAN|diamond]RecName: Full=Zinc finger protein 510;+++[ZN658_HUMAN|diamond]RecName: Full=Zinc finger protein 658;+++[ZNF3_HUMAN|diamond]RecName: Full=Zinc finger protein 3; AltName: Full=Zinc finger protein HF.12; AltName: Full=Zinc finger protein HZF3.1; AltName: Full=Zinc finger protein KOX25;"]
[107984449,"'LOC107984449'",0,2,1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0010494///cytoplasmic stress granule+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005730///nucleolus","GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000166///nucleotide binding","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","IPR005135///Endonuclease/exonuclease/phosphatase+++IPR019351///Protein of unknown function DUF2039+++IPR000477///Reverse transcriptase domain+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR004244///Transposase, L1+++IPR035301///L1 transposable element, trimerization domain+++IPR035300///L1 transposable element, dsRBD-like domain+++IPR013544///Domain of unknown function DUF1725","[CI085_HUMAN|diamond]RecName: Full=Uncharacterized protein C9orf85;+++[CN165_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00596;+++[CP089_HUMAN|diamond]RecName: Full=UPF0764 protein C16orf89; Flags: Precursor;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[GVQW2_HUMAN|diamond]RecName: Full=Protein GVQW2 {ECO:0000305}; AltName: Full=GVQW motif-containing protein 2 {ECO:0000312|HGNC:HGNC:51715};+++[LIN1_NYCCO|diamond]RecName: Full=LINE-1 reverse transcriptase homolog; EC=2.7.7.49;+++[LORF1_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein; Short=L1ORF1p; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1;+++[LORF1_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF1 protein {ECO:0000305}; Short=L1-ORF1p {ECO:0000303|PubMed:28806172}; AltName: Full=LINE retrotransposable element 1; AltName: Full=LINE1 retrotransposable element 1; AltName: Full=Transposase element L1Md-A101/L1Md-A102/L1Md-A2;+++[LORF2_HUMAN|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[LORF2_MOUSE|diamond]RecName: Full=LINE-1 retrotransposable element ORF2 protein; Short=ORF2p; AltName: Full=Long interspersed element-1; Short=L1; AltName: Full=Retrovirus-related Pol polyprotein LINE-1; Includes: RecName: Full=Reverse transcriptase; EC=2.7.7.49; Includes: RecName: Full=Endonuclease; EC=3.1.21.-;+++[PP5D1_HUMAN|diamond]RecName: Full=Protein PPP5D1; AltName: Full=PPP5 TPR repeat domain-containing protein 1;+++[UTY_PANTR|diamond]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously transcribed Y chromosome tetratricopeptide repeat protein;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;+++[ZN714_HUMAN|diamond]RecName: Full=Zinc finger protein 714;"]
[107985082,"'LOC107985082'",31,19,25,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"IPR032675///Leucine-rich repeat domain superfamily+++IPR015753///Leucine-rich repeat-containing protein 37+++IPR003591///Leucine-rich repeat, typical subtype+++IPR029423///LRRC37A/B like protein 1, C-terminal+++IPR032754///Leucine-rich repeat-containing protein 37, N-terminal+++IPR001611///Leucine-rich repeat","[L37A1_HUMAN|diamond]RecName: Full=Leucine-rich repeat-containing protein 37A; Flags: Precursor;+++[L37A2_HUMAN|diamond]RecName: Full=Leucine-rich repeat-containing protein 37A2; Flags: Precursor;+++[L37A3_HUMAN|diamond]RecName: Full=Leucine-rich repeat-containing protein 37A3; Flags: Precursor;"]
[107985939,"'LOC107985939'",19,18,18.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"IPR029058///Alpha/Beta hydrolase fold","[CH044_HUMAN|diamond]RecName: Full=Putative uncharacterized protein C8orf44;+++[CX062_HUMAN|diamond]RecName: Full=Putative uncharacterized protein encoded by LINC00269;+++[GVQW1_HUMAN|diamond]RecName: Full=Protein GVQW1; AltName: Full=GVQW motif-containing protein 1; AltName: Full=Tigger transposable element-derived 1-like protein 2; Flags: Precursor;+++[YG039_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ38264;+++[YS049_HUMAN|diamond]RecName: Full=Zinc finger protein ENSP00000375192;"]
[107986729,"'107986729'",0,1.12,0.56,{"$nulls":7},"IPR031572///Domain of unknown function DUF4705","[YG024_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ46235;+++[YG027_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ92257;+++[YJ013_HUMAN|diamond]RecName: Full=Putative uncharacterized protein FLJ44672;"]
[107987042,"'LOC107987042'",3,2,2.5,"04610///Complement and coagulation cascades","H00220///Factor V deficiency+++H00223///Inherited thrombophilia+++H01433///Budd-Chiari syndrome",{"$nulls":6},"[FA5_HUMAN|diamond]RecName: Full=Coagulation factor V; AltName: Full=Activated protein C cofactor; AltName: Full=Proaccelerin, labile factor; Contains: RecName: Full=Coagulation factor V heavy chain; Contains: RecName: Full=Coagulation factor V light chain; Flags: Precursor;"]
[107987372,"'LOC107987372'",5,2,3.5,{"$nulls":8},"[F201A_HUMAN|diamond]RecName: Full=Protein FAM201A;"]
[107987488,"'107987488'",0.23,0,0.115,{"$nulls":4},"GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0070317///negative regulation of G0 to G1 transition+++GO:0008285///negative regulation of cell proliferation+++GO:0006915///apoptotic process+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR009057///Homeobox-like domain superfamily+++IPR000047///Helix-turn-helix motif+++IPR001356///Homeobox domain","[DU4L2_HUMAN|diamond]RecName: Full=Double homeobox protein 4-like protein 2;+++[DU4L3_HUMAN|diamond]RecName: Full=Double homeobox protein 4-like protein 3;+++[DU4L5_HUMAN|diamond]RecName: Full=Double homeobox protein 4-like protein 5;+++[DU4L7_HUMAN|diamond]RecName: Full=Double homeobox protein 4-like protein 7;+++[DUX4_HUMAN|diamond]RecName: Full=Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}; AltName: Full=Double homeobox protein 10 {ECO:0000312|EMBL:AAK91509.1};"]
[10813,"'UTP14A'",349,245,297,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005634///nucleus+++GO:0032040///small-subunit processome+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis","IPR006709///Small-subunit processome, Utp14","[UT14A_HUMAN|Reviewed]RecName: Full=U3 small nucleolar RNA-associated protein 14 homolog A; AltName: Full=Antigen NY-CO-16; AltName: Full=Serologically defined colon cancer antigen 16;+++[X6RJY0_HUMAN|Unreviewed]SubName: Full=U3 small nucleolar RNA-associated protein 14 homolog A {ECO:0000313|Ensembl:ENSP00000413187}; Flags: Fragment;"]
[10848,"'PPP1R13L'",2115,2776,2445.5,"03460///Fanconi anemia pathway+++01524///Platinum drug resistance+++03420///Nucleotide excision repair","H00403///Disorders of nucleotide excision repair",null,null,"GO:0030054///cell junction+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge","GO:0045296///cadherin binding+++GO:0003714///transcription corepressor activity+++GO:0008134///transcription factor binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0048871///multicellular organismal homeostasis+++GO:0003229///ventricular cardiac muscle tissue development+++GO:0035264///multicellular organism growth+++GO:0006915///apoptotic process+++GO:0009791///post-embryonic development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0031076///embryonic camera-type eye development+++GO:0045597///positive regulation of cell differentiation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0042633///hair cycle+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0060048///cardiac muscle contraction","IPR020683///Ankyrin repeat-containing domain+++IPR028320///RelA-associated inhibitor+++IPR036028///SH3-like domain superfamily+++IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR001452///SH3 domain","[IASPP_HUMAN|Reviewed]RecName: Full=RelA-associated inhibitor; AltName: Full=Inhibitor of ASPP protein; Short=Protein iASPP; AltName: Full=NFkB-interacting protein 1; AltName: Full=PPP1R13B-like protein;+++[A0A024R0Q5_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1, regulatory (Inhibitor) subunit 13 like, isoform CRA_a {ECO:0000313|EMBL:EAW57345.1};+++[A7YME7_HUMAN|Unreviewed]SubName: Full=IASPP short isoform {ECO:0000313|EMBL:ABK76301.1}; SubName: Full=Protein phosphatase 1, regulatory (Inhibitor) subunit 13 like, isoform CRA_b {ECO:0000313|EMBL:EAW57344.1};+++[K7EML6_HUMAN|Unreviewed]SubName: Full=RelA-associated inhibitor {ECO:0000313|Ensembl:ENSP00000466555}; Flags: Fragment;+++[K7EN03_HUMAN|Unreviewed]SubName: Full=RelA-associated inhibitor {ECO:0000313|Ensembl:ENSP00000466730}; Flags: Fragment;+++[K7ENG6_HUMAN|Unreviewed]SubName: Full=RelA-associated inhibitor {ECO:0000313|Ensembl:ENSP00000466939}; Flags: Fragment;+++[K7EPP1_HUMAN|Unreviewed]SubName: Full=RelA-associated inhibitor {ECO:0000313|Ensembl:ENSP00000467471}; Flags: Fragment;"]
[10873,"'ME3'",639,623,631,"00710///Carbon fixation in photosynthetic organisms+++01200///Carbon metabolism+++01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments+++00620///Pyruvate metabolism",null,"M00172///C4-dicarboxylic acid cycle, NADP - malic enzyme type+++M00169///CAM (Crassulacean acid metabolism), light","R00216///(S)-Malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating)   (S)-Malate + NADP+ <=> Pyruvate + CO2 + NADPH + H+","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm","GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0048037///cofactor binding+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0004470///malic enzyme activity+++GO:0051287///NAD binding","GO:0009060///aerobic respiration+++GO:0072592///oxygen metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006099///tricarboxylic acid cycle+++GO:0006108///malate metabolic process+++GO:0006090///pyruvate metabolic process+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","IPR012301///Malic enzyme, N-terminal domain+++IPR036291///NAD(P)-binding domain superfamily+++IPR001891///Malic oxidoreductase+++IPR012302///Malic enzyme, NAD-binding+++IPR015884///Malic enzyme, conserved site+++IPR037062///Malic enzyme, N-terminal domain superfamily","[MAON_HUMAN|Reviewed]RecName: Full=NADP-dependent malic enzyme, mitochondrial; Short=NADP-ME; EC=1.1.1.40; AltName: Full=Malic enzyme 3; Flags: Precursor;+++[B2R995_HUMAN|Unreviewed]RecName: Full=Malic enzyme {ECO:0000256|RuleBase:RU003426};+++[Q6TCH8_HUMAN|Unreviewed]SubName: Full=Mitochondrial NADP(+)-dependent malic enzyme 3 {ECO:0000313|EMBL:AAR04784.1}; SubName: Full=NADP-dependent malic enzyme, mitochondrial {ECO:0000313|Ensembl:ENSP00000315255};"]
[10899,"'JTB'",1359,1150,1254.5,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0005813///centrosome","GO:0019901///protein kinase binding","GO:0051301///cell division+++GO:0000281///mitotic cytokinesis+++GO:0006915///apoptotic process+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0045860///positive regulation of protein kinase activity","IPR008657///Jumping translocation breakpoint","[JTB_HUMAN|Reviewed]RecName: Full=Protein JTB; AltName: Full=Jumping translocation breakpoint protein; AltName: Full=Prostate androgen-regulated protein; Short=PAR protein; Flags: Precursor;"]
[10916,"'MAGED2'",4044,3451,3747.5,{"$nulls":4},"GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0031093///platelet alpha granule lumen+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0002576///platelet degranulation+++GO:0070294///renal sodium ion absorption+++GO:0007565///female pregnancy","IPR028810///Melanoma-associated antigen D2+++IPR037445///Melanoma-associated antigen+++IPR002190///MAGE homology domain","[MAGD2_HUMAN|Reviewed]RecName: Full=Melanoma-associated antigen D2; AltName: Full=11B6; AltName: Full=Breast cancer-associated gene 1 protein; Short=BCG-1; AltName: Full=Hepatocellular carcinoma-associated protein JCL-1; AltName: Full=MAGE-D2 antigen;+++[A0A024R9Y7_HUMAN|Unreviewed]SubName: Full=Melanoma antigen family D, 2, isoform CRA_a {ECO:0000313|EMBL:EAW93195.1};+++[Q5H907_HUMAN|Unreviewed]SubName: Full=Melanoma antigen family D, 2, isoform CRA_d {ECO:0000313|EMBL:EAW93194.1}; SubName: Full=Melanoma-associated antigen D2 {ECO:0000313|Ensembl:ENSP00000364200};+++[Q5H909_HUMAN|Unreviewed]SubName: Full=Melanoma-associated antigen D2 {ECO:0000313|Ensembl:ENSP00000336962};"]
[10938,"'EHD1'",2937,2865,2901,"04144///Endocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0030139///endocytic vesicle+++GO:0043209///myelin sheath+++GO:0005769///early endosome+++GO:0060170///ciliary membrane+++GO:0020018///ciliary pocket membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0055038///recycling endosome membrane+++GO:0042995///cell projection+++GO:0005623///cell+++GO:0010008///endosome membrane+++GO:0031095///platelet dense tubular network membrane+++GO:0005929///cilium+++GO:0048471///perinuclear region of cytoplasm+++GO:0031901///early endosome membrane+++GO:0005811///lipid droplet","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0005525///GTP binding+++GO:0045296///cadherin binding+++GO:0017137///Rab GTPase binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding","GO:0061512///protein localization to cilium+++GO:0016197///endosomal transport+++GO:0042632///cholesterol homeostasis+++GO:2001137///positive regulation of endocytic recycling+++GO:0060271///cilium assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0031175///neuron projection development+++GO:0010886///positive regulation of cholesterol storage+++GO:0010976///positive regulation of neuron projection development+++GO:0006897///endocytosis+++GO:0015031///protein transport+++GO:0030030///cell projection organization+++GO:0034383///low-density lipoprotein particle clearance+++GO:1901741///positive regulation of myoblast fusion+++GO:0006886///intracellular protein transport+++GO:0051260///protein homooligomerization+++GO:0032456///endocytic recycling+++GO:0007596///blood coagulation","IPR002048///EF-hand domain+++IPR000261///EH domain+++IPR031692///EH domain-containing protein, N-terminal+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR022812///Dynamin superfamily+++IPR029951///EH domain-containing protein 1/3+++IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair+++IPR030381///Dynamin-type guanine nucleotide-binding (G) domain","[EHD1_HUMAN|Reviewed]RecName: Full=EH domain-containing protein 1 {ECO:0000305}; AltName: Full=PAST homolog 1 {ECO:0000303|PubMed:9253601}; Short=hPAST1 {ECO:0000303|PubMed:9253601}; AltName: Full=Testilin {ECO:0000312|EMBL:AAD45866.1};+++[A0A024R571_HUMAN|Unreviewed]SubName: Full=EH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000479153}; SubName: Full=EH-domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW74321.1};+++[B2R5U3_HUMAN|Unreviewed]SubName: Full=EH-domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW74318.1}; SubName: Full=cDNA FLJ40523 fis, clone TESTI2046872, highly similar to EH-domain-containing protein 1 {ECO:0000313|EMBL:BAG53542.1}; SubName: Full=cDNA, FLJ92624, highly similar to Homo sapiens EH-domain containing 1 (EHD1), mRNA {ECO:0000313|EMBL:BAG35240.1};+++[C9IZH1_HUMAN|Unreviewed]SubName: Full=EH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000399022}; Flags: Fragment;+++[C9J2Z4_HUMAN|Unreviewed]SubName: Full=EH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000391429}; Flags: Fragment;+++[C9JC03_HUMAN|Unreviewed]SubName: Full=EH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000404944}; Flags: Fragment;+++[C9JDQ8_HUMAN|Unreviewed]SubName: Full=EH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000396273}; Flags: Fragment;+++[C9JIJ3_HUMAN|Unreviewed]SubName: Full=EH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000403830}; Flags: Fragment;"]
[10953,"'TOMM34'",1648,1233,1440.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0031072///heat shock protein binding","GO:0006626///protein targeting to mitochondrion","IPR001440///Tetratricopeptide repeat 1+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR019734///Tetratricopeptide repeat+++IPR011990///Tetratricopeptide-like helical domain superfamily","[TOM34_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM34; Short=hTom34; AltName: Full=Translocase of outer membrane 34 kDa subunit;"]
[10971,"'YWHAQ'",3634,3834,3734,"04114///Oocyte meiosis+++05169///Epstein-Barr virus infection+++04391///Hippo signaling pathway - fly+++04212///Longevity regulating pathway - worm+++05203///Viral carcinogenesis+++04151///PI3K-Akt signaling pathway+++04013///MAPK signaling pathway - fly+++04390///Hippo signaling pathway+++05161///Hepatitis B+++04110///Cell cycle",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005925///focal adhesion","GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0044325///ion channel binding+++GO:0071889///14-3-3 protein binding+++GO:0047485///protein N-terminus binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding","GO:0021762///substantia nigra development+++GO:0034766///negative regulation of ion transmembrane transport+++GO:0061024///membrane organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway","IPR023410///14-3-3 domain+++IPR000308///14-3-3 protein+++IPR036815///14-3-3 domain superfamily+++IPR023409///14-3-3 protein, conserved site","[1433T_HUMAN|Reviewed]RecName: Full=14-3-3 protein theta; AltName: Full=14-3-3 protein T-cell; AltName: Full=14-3-3 protein tau; AltName: Full=Protein HS1;+++[E9PG15_HUMAN|Unreviewed]SubName: Full=14-3-3 protein theta {ECO:0000313|Ensembl:ENSP00000398990}; Flags: Fragment;+++[Q53RR5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein YWHAQ {ECO:0000313|EMBL:AAY24326.1}; Flags: Fragment;+++[Q53S41_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein YWHAQ {ECO:0000313|EMBL:AAX93143.1}; Flags: Fragment;+++[Q6LD62_HUMAN|Unreviewed]SubName: Full=14-3-3 protein protein ( cytosolic phospholipase A2protein ) {ECO:0000313|EMBL:AAD14300.1}; Flags: Fragment;"]
[10992,"'SF3B2'",4078,3835,3956.5,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0005654///nucleoplasm+++GO:0005686///U2 snRNP+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0005689///U12-type spliceosomal complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0016032///viral process+++GO:0000398///mRNA splicing, via spliceosome","IPR003034///SAP domain+++IPR007180///Domain of unknown function DUF382+++IPR006568///PSP, proline-rich","[SF3B2_HUMAN|Reviewed]RecName: Full=Splicing factor 3B subunit 2; AltName: Full=Pre-mRNA-splicing factor SF3b 145 kDa subunit; Short=SF3b145; AltName: Full=Spliceosome-associated protein 145; Short=SAP 145;+++[E9PIL8_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 2 {ECO:0000313|Ensembl:ENSP00000435765}; Flags: Fragment;+++[E9PJ04_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 2 {ECO:0000313|Ensembl:ENSP00000431908}; Flags: Fragment;+++[E9PJT3_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 2 {ECO:0000313|Ensembl:ENSP00000435495}; Flags: Fragment;+++[E9PPJ0_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 2 {ECO:0000313|Ensembl:ENSP00000432655};+++[H0YCG1_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 2 {ECO:0000313|Ensembl:ENSP00000431520}; Flags: Fragment;+++[H0YEX5_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 2 {ECO:0000313|Ensembl:ENSP00000436757}; Flags: Fragment;"]
[11016,"'ATF7'",388,516,452,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0034399///nuclear periphery+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0051019///mitogen-activated protein kinase binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0016032///viral process","IPR036236///Zinc finger C2H2 superfamily+++IPR004827///Basic-leucine zipper domain+++IPR013087///Zinc finger C2H2-type+++IPR016378///Transcription factor cyclic AMP-dependent, CRE-BP1-type","[ATF7_HUMAN|Reviewed]RecName: Full=Cyclic AMP-dependent transcription factor ATF-7; Short=cAMP-dependent transcription factor ATF-7; AltName: Full=Activating transcription factor 7; AltName: Full=Transcription factor ATF-A;+++[F8VWG7_HUMAN|Unreviewed]SubName: Full=Cyclic AMP-dependent transcription factor ATF-7 {ECO:0000313|Ensembl:ENSP00000449817}; Flags: Fragment;+++[K7EKZ7_HUMAN|Unreviewed]SubName: Full=Cyclic AMP-dependent transcription factor ATF-7 {ECO:0000313|Ensembl:ENSP00000465850}; Flags: Fragment;+++[K7ESA4_HUMAN|Unreviewed]SubName: Full=Cyclic AMP-dependent transcription factor ATF-7 {ECO:0000313|Ensembl:ENSP00000468623}; Flags: Fragment;"]
[11037,"'STON1'",116.05,173.95,145,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0000781///chromosome, telomeric region+++GO:0045111///intermediate filament cytoskeleton+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:1990879///CST complex+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0001650///fibrillar center+++GO:0005694///chromosome","GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0043047///single-stranded telomeric DNA binding+++GO:0003676///nucleic acid binding","GO:0006897///endocytosis+++GO:0016233///telomere capping+++GO:0045740///positive regulation of DNA replication+++GO:0000723///telomere maintenance+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0030100///regulation of endocytosis+++GO:0010833///telomere maintenance via telomere lengthening","IPR036168///AP-2 complex subunit mu, C-terminal superfamily+++IPR017110///Stonin+++IPR009088///Transcription factor IIA, beta-barrel+++IPR031232///Stonin-1+++IPR004855///Transcription factor IIA, alpha/beta subunit+++IPR012320///Stonin homology+++IPR028565///Mu homology domain","[STON1_HUMAN|Reviewed]RecName: Full=Stonin-1; AltName: Full=Stoned B-like factor;+++[B2RB25_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95267, highly similar to Homo sapiens stoned B-like factor (SBLF), mRNA {ECO:0000313|EMBL:BAG37072.1};+++[H7C1E2_HUMAN|Unreviewed]SubName: Full=Stonin-1 {ECO:0000313|Ensembl:ENSP00000399868}; Flags: Fragment;+++[Q0VAG7_HUMAN|Unreviewed]SubName: Full=STON1 protein {ECO:0000313|EMBL:AAI21065.1};+++[Q0VAG8_HUMAN|Unreviewed]SubName: Full=STON1 protein {ECO:0000313|EMBL:AAI21064.1};"]
[11057,"'ABHD2'",1969,3448,2708.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0031514///motile cilium+++GO:0005929///cilium+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0097524///sperm plasma membrane+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0036126///sperm flagellum","GO:0003707///steroid hormone receptor activity+++GO:0016298///lipase activity+++GO:0042562///hormone binding+++GO:0016787///hydrolase activity+++GO:0034338///short-chain carboxylesterase activity+++GO:0047372///acylglycerol lipase activity+++GO:0052689///carboxylic ester hydrolase activity","GO:0009611///response to wounding+++GO:0051793///medium-chain fatty acid catabolic process+++GO:0006629///lipid metabolic process+++GO:0016042///lipid catabolic process+++GO:0030336///negative regulation of cell migration+++GO:0044255///cellular lipid metabolic process+++GO:0048240///sperm capacitation+++GO:0051792///medium-chain fatty acid biosynthetic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0007340///acrosome reaction+++GO:0046464///acylglycerol catabolic process+++GO:0032570///response to progesterone","IPR000073///Alpha/beta hydrolase fold-1+++IPR012020///AB hydrolase 4 family+++IPR029058///Alpha/Beta hydrolase fold+++IPR000952///AB hydrolase 4, conserved site","[ABHD2_HUMAN|Reviewed]RecName: Full=Monoacylglycerol lipase ABHD2 {ECO:0000305}; EC=3.1.1.23 {ECO:0000269|PubMed:26989199}; AltName: Full=2-arachidonoylglycerol hydrolase {ECO:0000305}; AltName: Full=Abhydrolase domain-containing protein 2 {ECO:0000305}; AltName: Full=Lung alpha/beta hydrolase 2 {ECO:0000250|UniProtKB:Q9QXM0}; AltName: Full=Protein PHPS1-2 {ECO:0000303|PubMed:2843827};+++[A0A024RC89_HUMAN|Unreviewed]SubName: Full=Abhydrolase domain containing 2, isoform CRA_a {ECO:0000313|EMBL:EAX02035.1}; SubName: Full=Testicular tissue protein Li 6 {ECO:0000313|EMBL:AEE60919.1};+++[H3BMT2_HUMAN|Unreviewed]SubName: Full=Monoacylglycerol lipase ABHD2 {ECO:0000313|Ensembl:ENSP00000454531}; Flags: Fragment;+++[H3BN19_HUMAN|Unreviewed]SubName: Full=Monoacylglycerol lipase ABHD2 {ECO:0000313|Ensembl:ENSP00000454645}; Flags: Fragment;+++[H3BUZ6_HUMAN|Unreviewed]SubName: Full=Monoacylglycerol lipase ABHD2 {ECO:0000313|Ensembl:ENSP00000457882}; Flags: Fragment;"]
[11072,"'DUSP14'",677,507,592,null,"H01892///Peripheral T cell lymphoma (PTCL)+++H01601///Anaplastic large-cell lymphoma+++H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H01994///Lafora disease",{"$nulls":3},"GO:0003723///RNA binding+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0000188///inactivation of MAPK activity+++GO:0016311///dephosphorylation","IPR000340///Dual specificity phosphatase, catalytic domain+++IPR024950///Dual specificity phosphatase+++IPR016130///Protein-tyrosine phosphatase, active site+++IPR020420///Atypical dual specificity phosphatase, subfamily B+++IPR020417///Atypical dual specificity phosphatase+++IPR020422///Dual specificity protein phosphatase domain+++IPR029021///Protein-tyrosine phosphatase-like+++IPR000387///Tyrosine specific protein phosphatases domain","[DUS14_HUMAN|Reviewed]RecName: Full=Dual specificity protein phosphatase 14; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=MKP-1-like protein tyrosine phosphatase; Short=MKP-L; AltName: Full=Mitogen-activated protein kinase phosphatase 6; Short=MAP kinase phosphatase 6; Short=MKP-6;+++[Q6FI36_HUMAN|Unreviewed]SubName: Full=DUSP14 protein {ECO:0000313|EMBL:CAG38739.1}; SubName: Full=Dual specificity phosphatase 14, isoform CRA_a {ECO:0000313|EMBL:EAW57592.1}; SubName: Full=cDNA, FLJ95796, Homo sapiens dual specificity phosphatase 14 (DUSP14), mRNA {ECO:0000313|EMBL:BAG37408.1};"]
[11086,"'ADAM29'",6,2,4,"01100///Metabolic pathways",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0008237///metallopeptidase activity+++GO:0004222///metalloendopeptidase activity","GO:0007283///spermatogenesis+++GO:0006508///proteolysis","IPR036436///Disintegrin domain superfamily+++IPR018358///Disintegrin, conserved site+++IPR006586///ADAM, cysteine-rich+++IPR001590///Peptidase M12B, ADAM/reprolysin+++IPR001762///Disintegrin domain+++IPR002870///Peptidase M12B, propeptide+++IPR024079///Metallopeptidase, catalytic domain superfamily+++IPR034027///Reprolysin domain, adamalysin-type","[ADA29_HUMAN|Reviewed]RecName: Full=Disintegrin and metalloproteinase domain-containing protein 29; Short=ADAM 29; AltName: Full=Cancer/testis antigen 73; Short=CT73; Flags: Precursor;+++[A0A140VJD8_HUMAN|Unreviewed]SubName: Full=Testis secretory sperm-binding protein Li 207a {ECO:0000313|EMBL:AEE60925.1};+++[D6RBU0_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 29 {ECO:0000313|Ensembl:ENSP00000422537}; Flags: Fragment;+++[D6RHU0_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 29 {ECO:0000313|Ensembl:ENSP00000427674}; Flags: Fragment;+++[D6RIU9_HUMAN|Unreviewed]SubName: Full=Disintegrin and metalloproteinase domain-containing protein 29 {ECO:0000313|Ensembl:ENSP00000427370}; Flags: Fragment;"]
[11104,"'KATNA1'",79,71,75,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005815///microtubule organizing center+++GO:0097431///mitotic spindle pole+++GO:0000922///spindle pole+++GO:0030496///midbody+++GO:0005856///cytoskeleton+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0005819///spindle","GO:0005524///ATP binding+++GO:0016853///isomerase activity+++GO:0008568///microtubule-severing ATPase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0016887///ATPase activity","GO:0007049///cell cycle+++GO:0051013///microtubule severing+++GO:0051301///cell division+++GO:0007283///spermatogenesis+++GO:0031122///cytoplasmic microtubule organization","IPR003593///AAA+ ATPase domain+++IPR003959///ATPase, AAA-type, core+++IPR015415///Vps4 oligomerisation, C-terminal+++IPR028596///Katanin p60 subunit A1+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003960///ATPase, AAA-type, conserved site","[KTNA1_HUMAN|Reviewed]RecName: Full=Katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}; Short=Katanin p60 subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}; EC=3.6.4.3 {ECO:0000255|HAMAP-Rule:MF_03023}; AltName: Full=p60 katanin {ECO:0000255|HAMAP-Rule:MF_03023};+++[A8K7S5_HUMAN|Unreviewed]RecName: Full=Katanin p60 ATPase-containing subunit A1 {ECO:0000256|HAMAP-Rule:MF_03023}; Short=Katanin p60 subunit A1 {ECO:0000256|HAMAP-Rule:MF_03023}; EC=3.6.4.3 {ECO:0000256|HAMAP-Rule:MF_03023}; AltName: Full=p60 katanin {ECO:0000256|HAMAP-Rule:MF_03023};+++[B7ZBC8_HUMAN|Unreviewed]SubName: Full=Katanin p60 ATPase-containing subunit A1 {ECO:0000313|Ensembl:ENSP00000390322}; Flags: Fragment;+++[B7ZBC9_HUMAN|Unreviewed]SubName: Full=Katanin p60 ATPase-containing subunit A1 {ECO:0000313|Ensembl:ENSP00000398993}; Flags: Fragment;"]
[11124,"'FAF1'",373,357,365,"04217///Necroptosis+++04624///Toll and Imd signaling pathway",{"$nulls":3},"GO:0034098///VCP-NPL4-UFD1 AAA ATPase complex+++GO:0031265///CD95 death-inducing signaling complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005635///nuclear envelope+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0016021///integral component of membrane","GO:0019901///protein kinase binding+++GO:0043130///ubiquitin binding+++GO:0019887///protein kinase regulator activity+++GO:0051059///NF-kappaB binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0031334///positive regulation of protein complex assembly+++GO:0006915///apoptotic process+++GO:0008219///cell death+++GO:0045740///positive regulation of DNA replication+++GO:0042176///regulation of protein catabolic process+++GO:0030155///regulation of cell adhesion+++GO:0010942///positive regulation of cell death+++GO:1903364///positive regulation of cellular protein catabolic process+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0045859///regulation of protein kinase activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043065///positive regulation of apoptotic process","IPR036249///Thioredoxin-like superfamily+++IPR006577///UAS+++IPR001012///UBX domain+++IPR033043///FAS-associated factor 1, UBX domain+++IPR029071///Ubiquitin-like domain superfamily","[FAF1_HUMAN|Reviewed]RecName: Full=FAS-associated factor 1; Short=hFAF1; AltName: Full=UBX domain-containing protein 12; AltName: Full=UBX domain-containing protein 3A;+++[B1ANM7_HUMAN|Unreviewed]SubName: Full=FAS-associated factor 1 {ECO:0000313|Ensembl:ENSP00000360843};+++[B3KT28_HUMAN|Unreviewed]SubName: Full=cDNA FLJ37524 fis, clone BRCAN2007119, highly similar to FAS-associated factor 1 {ECO:0000313|EMBL:BAG52940.1};"]
[11141,"'IL1RAPL1'",1,0,0.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0045211///postsynaptic membrane+++GO:0030425///dendrite+++GO:0030424///axon+++GO:0016021///integral component of membrane+++GO:0098978///glutamatergic synapse+++GO:0009986///cell surface+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005245///voltage-gated calcium channel activity+++GO:0019966///interleukin-1 binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding","GO:0045920///negative regulation of exocytosis+++GO:0007165///signal transduction+++GO:0099545///trans-synaptic signaling by trans-synaptic complex+++GO:0030182///neuron differentiation+++GO:0071345///cellular response to cytokine stimulus+++GO:0097105///presynaptic membrane assembly+++GO:0099175///regulation of postsynapse organization+++GO:0051965///positive regulation of synapse assembly+++GO:1905606///regulation of presynapse assembly+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0070588///calcium ion transmembrane transport+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0010975///regulation of neuron projection development","IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR015621///Interleukin-1 receptor family+++IPR013151///Immunoglobulin+++IPR003599///Immunoglobulin subtype+++IPR000157///Toll/interleukin-1 receptor homology (TIR) domain+++IPR003598///Immunoglobulin subtype 2+++IPR035897///Toll/interleukin-1 receptor homology (TIR) domain superfamily","[IRPL1_HUMAN|Reviewed]RecName: Full=Interleukin-1 receptor accessory protein-like 1; Short=IL-1-RAPL-1; Short=IL-1RAPL-1; Short=IL1RAPL-1; AltName: Full=Oligophrenin-4; AltName: Full=Three immunoglobulin domain-containing IL-1 receptor-related 2; Short=TIGIRR-2; AltName: Full=X-linked interleukin-1 receptor accessory protein-like 1; Flags: Precursor;+++[A0A0A0MR17_HUMAN|Unreviewed]SubName: Full=Interleukin-1 receptor accessory protein-like 1 {ECO:0000313|Ensembl:ENSP00000305200};+++[Q7Z2H0_HUMAN|Unreviewed]SubName: Full=Interleukin 1 receptor accessory protein-like 1 {ECO:0000313|EMBL:BAC80450.1}; Flags: Fragment;+++[Q7Z2K4_HUMAN|Unreviewed]SubName: Full=Interleukin 1 receptor accessory protein-like 1 {ECO:0000313|EMBL:BAC80459.1}; Flags: Fragment;+++[X5DNQ7_HUMAN|Unreviewed]SubName: Full=Interleukin 1 receptor accessory protein-like 1 isoform A {ECO:0000313|EMBL:AHW56511.1}; Flags: Fragment;"]
[11158,"'RABL2B'",549.33,595.42,572.375,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0000242///pericentriolar material+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0005814///centriole+++GO:0042995///cell projection","GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0006886///intracellular protein transport+++GO:0032482///Rab protein signal transduction+++GO:0060271///cilium assembly+++GO:0042073///intraciliary transport+++GO:0030030///cell projection organization","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001806///Small GTPase+++IPR005225///Small GTP-binding protein domain","[RBL2B_HUMAN|Reviewed]RecName: Full=Rab-like protein 2B;+++[A0A0S2SW46_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|EMBL:ALP46109.1};+++[A8MXF6_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000378956};+++[C9JFZ0_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000415180}; Flags: Fragment;+++[F2Z2T3_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000378955};+++[F2Z3A9_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000419811};+++[F2Z3J7_HUMAN|Unreviewed]SubName: Full=Rab-like protein 2B {ECO:0000313|Ensembl:ENSP00000398282};"]
[11174,"'ADAMTS6'",195,357,276,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0008233///peptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0007507///heart development+++GO:0035904///aorta development+++GO:0003279///cardiac septum development+++GO:0006508///proteolysis+++GO:0060976///coronary vasculature development","IPR010294///ADAM-TS Spacer 1+++IPR001590///Peptidase M12B, ADAM/reprolysin+++IPR013273///ADAMTS/ADAMTS-like+++IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR024079///Metallopeptidase, catalytic domain superfamily+++IPR010909///PLAC+++IPR000884///Thrombospondin type-1 (TSP1) repeat+++IPR002870///Peptidase M12B, propeptide","[ATS6_HUMAN|Reviewed]RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 6; Short=ADAM-TS 6; Short=ADAM-TS6; Short=ADAMTS-6; EC=3.4.24.-; Flags: Precursor;+++[Q5IR90_HUMAN|Unreviewed]SubName: Full=ADAMTS6 variant 2 {ECO:0000313|EMBL:AAW47396.1}; Flags: Fragment;"]
[11190,"'CEP250'",675,563,619,{"$nulls":4},"GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0032991///protein-containing complex+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005929///cilium+++GO:0005814///centriole","GO:0019901///protein kinase binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding","GO:0008104///protein localization+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0010457///centriole-centriole cohesion+++GO:0033365///protein localization to organelle+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1905515///non-motile cilium assembly+++GO:0030997///regulation of centriole-centriole cohesion+++GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:1904781///positive regulation of protein localization to centrosome","IPR026048///Centrosome-associated protein CEP250","[CP250_HUMAN|Reviewed]RecName: Full=Centrosome-associated protein CEP250; AltName: Full=250 kDa centrosomal protein; Short=Cep250; AltName: Full=Centrosomal Nek2-associated protein 1; Short=C-Nap1; AltName: Full=Centrosomal protein 2;+++[A0A087WZ34_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000482323}; Flags: Fragment;+++[A6PVI9_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 250kDa {ECO:0000313|EMBL:CAO03345.1}; SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000380658};+++[A6PVJ0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 250kDa {ECO:0000313|EMBL:CAO03346.1}; Flags: Fragment;+++[E7ETF9_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000413827}; Flags: Fragment;+++[E9PHT2_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000419137};+++[G1UI40_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 250kDa {ECO:0000313|EMBL:BAK64163.1}; Flags: Fragment;+++[H0Y5R2_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000400200}; Flags: Fragment;+++[H7C0D6_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000394346}; Flags: Fragment;+++[H7C0P0_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000395992}; Flags: Fragment;+++[Q5JWS5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 250kDa {ECO:0000313|EMBL:CAI42840.1}; SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000398747}; Flags: Fragment;+++[Q5JWS6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 250kDa {ECO:0000313|EMBL:CAI42839.1}; SubName: Full=Centrosome-associated protein CEP250 {ECO:0000313|Ensembl:ENSP00000414651}; Flags: Fragment;+++[Q6IPL3_HUMAN|Unreviewed]SubName: Full=CEP250 protein {ECO:0000313|EMBL:AAH71869.1};"]
[11216,"'AKAP10'",249,267,258,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm","GO:0051018///protein kinase A binding+++GO:0005515///protein binding+++GO:0016301///kinase activity","GO:0007165///signal transduction+++GO:0007596///blood coagulation+++GO:0016310///phosphorylation+++GO:0008104///protein localization","IPR036305///RGS domain superfamily+++IPR016137///RGS domain+++IPR037719///A-kinase anchor protein 10, PKA-binding (AKB) domain","[AKA10_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 10, mitochondrial; Short=AKAP-10; AltName: Full=Dual specificity A kinase-anchoring protein 2; Short=D-AKAP-2; AltName: Full=Protein kinase A-anchoring protein 10; Short=PRKA10; Flags: Precursor;+++[A0A0S2Z4Y8_HUMAN|Unreviewed]SubName: Full=A kinase anchor protein 10 isoform 3 {ECO:0000313|EMBL:ALQ34006.1}; Flags: Fragment;+++[A0A0S2Z4Z7_HUMAN|Unreviewed]SubName: Full=A kinase anchor protein 10 isoform 1 {ECO:0000313|EMBL:ALQ34004.1}; Flags: Fragment;+++[A0A0S2Z513_HUMAN|Unreviewed]SubName: Full=A kinase anchor protein 10 isoform 2 {ECO:0000313|EMBL:ALQ34005.1};+++[A0A0S2Z551_HUMAN|Unreviewed]SubName: Full=A kinase anchor protein 10 isoform 5 {ECO:0000313|EMBL:ALQ34008.1}; Flags: Fragment;+++[A0A0S2Z5A1_HUMAN|Unreviewed]SubName: Full=A kinase anchor protein 10 isoform 4 {ECO:0000313|EMBL:ALQ34007.1};+++[E7EMD6_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000378907};+++[I3L177_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000458637}; Flags: Fragment;+++[I3L479_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000461040};+++[I3NI04_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000461793};+++[J3QL61_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000463398}; Flags: Fragment;+++[J3QR74_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000464079};+++[J3QRM7_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000464294}; Flags: Fragment;+++[K7EM25_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 10, mitochondrial {ECO:0000313|Ensembl:ENSP00000466329}; Flags: Fragment;"]
[112267882,"'112267882'",0,1.4,0.7,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0031225///anchored component of membrane",null,"GO:0007605///sensory perception of sound+++GO:0007160///cell-matrix adhesion","IPR026663///Otoancorin+++IPR026664///Stereocilin-related","[OTOAN_HUMAN|diamond]RecName: Full=Otoancorin; Flags: Precursor;+++[OTOAN_MOUSE|diamond]RecName: Full=Otoancorin; Flags: Precursor;+++[STRC_HUMAN|diamond]RecName: Full=Stereocilin; Flags: Precursor;+++[STRCL_HUMAN|diamond]RecName: Full=Putative stereocilin-like protein; AltName: Full=Stereocilin pseudogene 1; Flags: Precursor;+++[STRC_MOUSE|diamond]RecName: Full=Stereocilin; Flags: Precursor;"]
[112268105,"'LOC112268105'",3,5,4,{"$nulls":6},"GO:0006355///regulation of transcription, DNA-templated","IPR026741///Protein strawberry notch+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR026937///Strawberry notch, helicase C domain+++IPR039187///Strawberry notch, AAA domain","[A0A2K5DXE9_AOTNA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSANAP00000025582};"]
[112268338,"'112268338'",6,0,3,"04927///Cortisol synthesis and secretion+++00140///Steroid hormone biosynthesis+++04934///Cushing's syndrome+++04925///Aldosterone synthesis and secretion+++01100///Metabolic pathways","H00599///46,XX disorders of sex development (Disorders related to androgen excess)+++H00216///Congenital adrenal hyperplasia (CAH)","M00109///C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone+++M00108///C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone","R03849///11beta-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) 11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Corticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O+++R02213///progesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) Progesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycorticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O+++R03784///pregnenolone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) Pregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 21-Hydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O+++R02838///21-deoxycortisol,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) 21-Deoxycortisol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Cortisol + [Oxidized NADPH---hemoprotein reductase] + H2O+++R04675///17alpha-hydroxypregnenolone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) 17alpha-Hydroxypregnenolone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 17alpha,21-Dihydroxypregnenolone + [Oxidized NADPH---hemoprotein reductase] + H2O+++R03326///17alpha-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating) 17alpha-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 11-Deoxycortisol + [Oxidized NADPH---hemoprotein reductase] + H2O","GO:0031090///organelle membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0005496///steroid binding+++GO:0004509///steroid 21-monooxygenase activity+++GO:0020037///heme binding+++GO:0008395///steroid hydroxylase activity+++GO:0005506///iron ion binding","GO:0006694///steroid biosynthetic process+++GO:0016125///sterol metabolic process+++GO:0008202///steroid metabolic process+++GO:0006704///glucocorticoid biosynthetic process+++GO:0006705///mineralocorticoid biosynthetic process","IPR017972///Cytochrome P450, conserved site+++IPR002401///Cytochrome P450, E-class, group I+++IPR036396///Cytochrome P450 superfamily+++IPR001128///Cytochrome P450","[CP21A_BOVIN|diamond]RecName: Full=Steroid 21-hydroxylase; EC=1.14.14.16 {ECO:0000269|PubMed:22262854}; AltName: Full=21-OHase; AltName: Full=Cytochrome P-450c21; AltName: Full=Cytochrome P450 21; AltName: Full=Cytochrome P450 XXI; AltName: Full=Cytochrome P450-C21;+++[CP21A_CANLF|diamond]RecName: Full=Steroid 21-hydroxylase; EC=1.14.14.16 {ECO:0000250|UniProtKB:P00191}; AltName: Full=21-OHase; AltName: Full=Cytochrome P-450c21; AltName: Full=Cytochrome P450 21; AltName: Full=Cytochrome P450 XXI; AltName: Full=Cytochrome P450-C21;+++[CP21A_FELCA|diamond]RecName: Full=Steroid 21-hydroxylase; EC=1.14.14.16 {ECO:0000250|UniProtKB:P00191}; AltName: Full=21-OHase; AltName: Full=Cytochrome P-450c21; AltName: Full=Cytochrome P450 21; AltName: Full=Cytochrome P450 XXI; AltName: Full=Cytochrome P450-C21;+++[CP21A_HUMAN|diamond]RecName: Full=Steroid 21-hydroxylase; EC=1.14.14.16 {ECO:0000269|PubMed:16984992, ECO:0000269|PubMed:22014889, ECO:0000269|PubMed:25855791, ECO:0000269|PubMed:27721825}; AltName: Full=21-OHase; AltName: Full=Cytochrome P-450c21; AltName: Full=Cytochrome P450 21; AltName: Full=Cytochrome P450 XXI; AltName: Full=Cytochrome P450-C21; AltName: Full=Cytochrome P450-C21B;+++[CP21A_LYNLY|diamond]RecName: Full=Steroid 21-hydroxylase; EC=1.14.14.16 {ECO:0000250|UniProtKB:P00191}; AltName: Full=21-OHase; AltName: Full=Cytochrome P-450c21; AltName: Full=Cytochrome P450 21; AltName: Full=Cytochrome P450 XXI; AltName: Full=Cytochrome P450-C21;+++[CP21A_PIG|diamond]RecName: Full=Steroid 21-hydroxylase; EC=1.14.14.16 {ECO:0000250|UniProtKB:P00191}; AltName: Full=21-OHase; AltName: Full=Cytochrome P-450c21; AltName: Full=Cytochrome P450 21; AltName: Full=Cytochrome P450 XXI; AltName: Full=Cytochrome P450-C21;"]
[112268409,"'112268409'",1,0,0.5]
[112268453,"'112268453'",1,2,1.5,{"$nulls":4},"GO:0000794///condensed nuclear chromosome+++GO:0016605///PML body+++GO:0015629///actin cytoskeleton+++GO:0001673///male germ cell nucleus","GO:0042802///identical protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation","IPR036420///BRCT domain superfamily+++IPR035960///Secretoglobin superfamily+++IPR001357///BRCT domain","[A0A2K5TTP1_MACFA|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMFAP00000003425};+++[A0A2K6B637_MACNE|diamond]SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMNEP00000006873};"]
[11240,"'PADI2'",2480,3745,3112.5,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01796///Uncombable hair syndrome",null,null,"GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0035578///azurophil granule lumen+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0035327///transcriptionally active chromatin+++GO:0005634///nucleus","GO:0030331///estrogen receptor binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0016787///hydrolase activity+++GO:0004668///protein-arginine deiminase activity+++GO:0042803///protein homodimerization activity","GO:0010848///regulation of chromatin disassembly+++GO:0018101///protein citrullination+++GO:0036414///histone citrullination+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0036413///histone H3-R26 citrullination+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0070100///negative regulation of chemokine-mediated signaling pathway+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0021762///substantia nigra development+++GO:1901624///negative regulation of lymphocyte chemotaxis","IPR036556///Protein-arginine deiminase, central domain superfamily+++IPR013733///Protein-arginine deiminase (PAD), central domain+++IPR004303///Protein-arginine deiminase+++IPR013530///Protein-arginine deiminase, C-terminal+++IPR008972///Cupredoxin+++IPR038685///PAD, N-terminal domain superfamily+++IPR013732///Protein-arginine deiminase (PAD) N-terminal","[PADI2_HUMAN|Reviewed]RecName: Full=Protein-arginine deiminase type-2; EC=3.5.3.15 {ECO:0000269|PubMed:12392711, ECO:0000269|PubMed:25621824}; AltName: Full=PAD-H19; AltName: Full=Peptidylarginine deiminase II {ECO:0000303|PubMed:12392711}; AltName: Full=Protein-arginine deiminase type II;+++[A0A024RA98_HUMAN|Unreviewed]SubName: Full=Peptidyl arginine deiminase, type II, isoform CRA_a {ECO:0000313|EMBL:EAW94831.1};"]
[11258,"'DCTN3'",521,411,466,{"$nulls":4},"GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0005869///dynactin complex+++GO:0005856///cytoskeleton+++GO:0032154///cleavage furrow+++GO:0005815///microtubule organizing center+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex+++GO:0000775///chromosome, centromeric region+++GO:0030496///midbody+++GO:0005730///nucleolus+++GO:0005813///centrosome","GO:0005198///structural molecule activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0051301///cell division+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007017///microtubule-based process+++GO:0061640///cytoskeleton-dependent cytokinesis+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0000278///mitotic cell cycle","IPR009991///Dynactin subunit p22","[DCTN3_HUMAN|Reviewed]RecName: Full=Dynactin subunit 3; AltName: Full=Dynactin complex subunit 22 kDa subunit; Short=p22;+++[A0A0A0MRV8_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 3 {ECO:0000313|Ensembl:ENSP00000368191}; Flags: Fragment;+++[Q8NB28_HUMAN|Unreviewed]SubName: Full=Dynactin 3 (P22), isoform CRA_a {ECO:0000313|EMBL:EAW58439.1}; SubName: Full=cDNA FLJ34342 fis, clone FEBRA2009986, moderately similar to Dynactin 3 (p22); dynactin light chain {ECO:0000313|EMBL:BAC03716.1};+++[X6RA56_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 3 {ECO:0000313|Ensembl:ENSP00000368193};+++[X6RCK5_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 3 {ECO:0000313|Ensembl:ENSP00000390842}; Flags: Fragment;+++[X6RLR1_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 3 {ECO:0000313|Ensembl:ENSP00000432915};"]
[11273,"'ATXN2L'",4488,5116,4802,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0045296///cadherin binding","GO:0010603///regulation of cytoplasmic mRNA processing body assembly+++GO:0034063///stress granule assembly","IPR009818///Ataxin-2, C-terminal+++IPR009604///LsmAD domain+++IPR025852///Ataxin 2, SM domain","[ATX2L_HUMAN|Reviewed]RecName: Full=Ataxin-2-like protein; AltName: Full=Ataxin-2 domain protein; AltName: Full=Ataxin-2-related protein;+++[A0A024QZ91_HUMAN|Unreviewed]SubName: Full=Ataxin 2-like, isoform CRA_a {ECO:0000313|EMBL:EAW51996.1};+++[A0A024QZB7_HUMAN|Unreviewed]SubName: Full=Ataxin 2-like, isoform CRA_b {ECO:0000313|EMBL:EAW51989.1};+++[A0A024QZC0_HUMAN|Unreviewed]SubName: Full=Ataxin 2-like, isoform CRA_e {ECO:0000313|EMBL:EAW51994.1};+++[A0A0C4DGL7_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000454757}; Flags: Fragment;+++[H3BMX1_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000454588}; Flags: Fragment;+++[H3BPQ7_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000455427}; Flags: Fragment;+++[H3BQ14_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000455560}; Flags: Fragment;+++[H3BQX7_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000455981}; Flags: Fragment;+++[H3BRB0_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000456162}; Flags: Fragment;+++[H3BSK9_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000456752}; Flags: Fragment;+++[H3BSQ5_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000456812}; Flags: Fragment;+++[H3BUE3_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000457599}; Flags: Fragment;+++[H3BUF6_HUMAN|Unreviewed]SubName: Full=Ataxin-2-like protein {ECO:0000313|Ensembl:ENSP00000457613};"]
[112840,"'WDR89'",78,56,67,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR039328///WD repeat-containing protein 89+++IPR036322///WD40-repeat-containing domain superfamily+++IPR001680///WD40 repeat+++IPR017986///WD40-repeat-containing domain+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[WDR89_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 89;+++[A0A024R667_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 150, isoform CRA_a {ECO:0000313|EMBL:EAW80832.1};+++[G3V4B8_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 89 {ECO:0000313|Ensembl:ENSP00000451702}; Flags: Fragment;"]
[11309,"'SLCO2B1'",0,2,1,{"$nulls":4},"GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0015347///sodium-independent organic anion transmembrane transporter activity+++GO:0015125///bile acid transmembrane transporter activity+++GO:0008514///organic anion transmembrane transporter activity+++GO:0005215///transporter activity","GO:0055085///transmembrane transport+++GO:0001889///liver development+++GO:0071718///sodium-independent icosanoid transport+++GO:0043252///sodium-independent organic anion transport+++GO:0015721///bile acid and bile salt transport+++GO:0006811///ion transport","IPR020846///Major facilitator superfamily domain+++IPR002350///Kazal domain+++IPR036259///MFS transporter superfamily+++IPR004156///Organic anion transporter polypeptide","[SO2B1_HUMAN|Reviewed]RecName: Full=Solute carrier organic anion transporter family member 2B1; AltName: Full=Organic anion transporter B; Short=OATP-B; AltName: Full=Organic anion transporter polypeptide-related protein 2; Short=OATP-RP2; Short=OATPRP2; AltName: Full=Solute carrier family 21 member 9;+++[A0A024R5I4_HUMAN|Unreviewed]RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};+++[A0A0A0MTF1_HUMAN|Unreviewed]RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};+++[A0A1B0GX35_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family member 2B1 {ECO:0000313|Ensembl:ENSP00000435384}; Flags: Fragment;+++[C7BWB6_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family, member 2B1 {ECO:0000313|EMBL:CAR64268.1}; Flags: Fragment;+++[C7BWB7_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family, member 2B1 {ECO:0000313|EMBL:CAR64269.1}; Flags: Fragment;+++[E9PI53_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family member 2B1 {ECO:0000313|Ensembl:ENSP00000436513}; Flags: Fragment;+++[E9PIU9_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family member 2B1 {ECO:0000313|Ensembl:ENSP00000433872}; Flags: Fragment;+++[E9PN87_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family member 2B1 {ECO:0000313|Ensembl:ENSP00000432889}; Flags: Fragment;+++[E9PRW4_HUMAN|Unreviewed]RecName: Full=Solute carrier organic anion transporter family member {ECO:0000256|RuleBase:RU362056};+++[H0YE11_HUMAN|Unreviewed]SubName: Full=Solute carrier organic anion transporter family member 2B1 {ECO:0000313|Ensembl:ENSP00000434742}; Flags: Fragment;"]
[11318,"'GPR182'",3,0,1.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004930///G protein-coupled receptor activity","GO:0007166///cell surface receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR001350///G10D orphan receptor+++IPR017452///GPCR, rhodopsin-like, 7TM","[GP182_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor 182;+++[A0A0D9SG31_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 182 {ECO:0000313|Ensembl:ENSP00000487111}; Flags: Fragment;+++[Q6LAJ3_HUMAN|Unreviewed]SubName: Full=G-protein coupled receptor {ECO:0000313|EMBL:CAC79687.1};+++[Q7Z4H2_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 182 {ECO:0000313|Ensembl:ENSP00000486086}; SubName: Full=HBcAg-binding protein {ECO:0000313|EMBL:AAQ09605.1};"]
[113277,"'TMEM106A'",124.48,119,121.74,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process","IPR009790///Protein of unknown function DUF1356, TMEM106","[T106A_HUMAN|Reviewed]RecName: Full=Transmembrane protein 106A;+++[B7Z779_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50717, highly similar to Transmembrane protein 106A {ECO:0000313|EMBL:BAH13515.1};+++[K7ERE2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 106A {ECO:0000313|Ensembl:ENSP00000468220}; Flags: Fragment;"]
[113402,"'SFT2D1'",180,177,178.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:0016192///vesicle-mediated transport+++GO:0015031///protein transport","IPR011691///Vesicle transport protein SFT2+++IPR007305///Vesicle transport protein, Got1/SFT2-like","[SFT2A_HUMAN|Reviewed]RecName: Full=Vesicle transport protein SFT2A; AltName: Full=SFT2 domain-containing protein 1; AltName: Full=pRGR1;+++[Q4G178_HUMAN|Unreviewed]SubName: Full=SFT2D1 protein {ECO:0000313|EMBL:AAH28388.1};"]
[113622,"'ADPRHL1'",14,10,12,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005622///intracellular+++GO:0012505///endomembrane system","GO:0016787///hydrolase activity+++GO:0000287///magnesium ion binding+++GO:0003875///ADP-ribosylarginine hydrolase activity","GO:0051725///protein de-ADP-ribosylation","IPR012108///ADP-ribosylarginine hydrolase+++IPR036705///ADP-ribosylation/Crystallin J1 superfamily+++IPR005502///ADP-ribosylation/Crystallin J1","[ARHL1_HUMAN|Reviewed]RecName: Full=[Protein ADP-ribosylarginine] hydrolase-like protein 1; EC=3.2.-.-; AltName: Full=ADP-ribosylhydrolase 2;+++[A0A0U1RQK4_HUMAN|Unreviewed]SubName: Full=[Protein ADP-ribosylarginine] hydrolase-like protein 1 {ECO:0000313|Ensembl:ENSP00000489048};+++[X6RL45_HUMAN|Unreviewed]SubName: Full=[Protein ADP-ribosylarginine] hydrolase-like protein 1 {ECO:0000313|Ensembl:ENSP00000416213}; Flags: Fragment;"]
[114034,"'TOE1'",59,69,64,null,"H00897///Pontocerebellar hypoplasia",null,null,"GO:0005654///nucleoplasm+++GO:0015030///Cajal body+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0017069///snRNA binding+++GO:0046872///metal ion binding","GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0034472///snRNA 3'-end processing","IPR006941///Ribonuclease CAF1+++IPR036397///Ribonuclease H superfamily+++IPR036855///Zinc finger, CCCH-type superfamily+++IPR000571///Zinc finger, CCCH-type+++IPR012337///Ribonuclease H-like superfamily","[TOE1_HUMAN|Reviewed]RecName: Full=Target of EGR1 protein 1;"]
[114625,"'ERMAP'",277,365,321,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane","GO:0005102///signaling receptor binding","GO:0050852///T cell receptor signaling pathway+++GO:0050776///regulation of immune response","IPR013106///Immunoglobulin V-set domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR006574///SPRY-associated+++IPR003879///Butyrophylin-like, SPRY domain+++IPR001870///B30.2/SPRY domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold+++IPR003877///SPRY domain","[ERMAP_HUMAN|Reviewed]RecName: Full=Erythroid membrane-associated protein; Short=hERMAP; AltName: Full=Radin blood group antigen; AltName: Full=Scianna blood group antigen; Flags: Precursor;+++[A0A1C9HIH9_HUMAN|Unreviewed]SubName: Full=Erythroblast membrane-associated protein {ECO:0000313|EMBL:AOO79046.1};+++[A0A1C9HIK4_HUMAN|Unreviewed]SubName: Full=Erythroblast membrane-associated protein {ECO:0000313|EMBL:AOO79070.1};+++[A0A1C9HIM0_HUMAN|Unreviewed]SubName: Full=Erythroblast membrane-associated protein {ECO:0000313|EMBL:AOO79077.1};+++[A0A2H4ZEU9_HUMAN|Unreviewed]SubName: Full=Scianna blood group antigen {ECO:0000313|EMBL:AUF74449.1}; Flags: Fragment;+++[A0A2H4ZEV2_HUMAN|Unreviewed]SubName: Full=Scianna blood group antigen {ECO:0000313|EMBL:AUF74450.1}; Flags: Fragment;+++[A0A2R8YH65_HUMAN|Unreviewed]SubName: Full=Erythroid membrane-associated protein {ECO:0000313|Ensembl:ENSP00000496530}; Flags: Fragment;+++[G4XL73_HUMAN|Unreviewed]SubName: Full=Nonfunctional erythroid membrane-associated protein {ECO:0000313|EMBL:AEP25628.1}; Flags: Fragment;+++[L8EA32_HUMAN|Unreviewed]SubName: Full=Alternative protein ERMAP {ECO:0000313|EMBL:CCQ43601.1};"]
[114792,"'KLHL32'",10.57,19.97,15.27,{"$nulls":4},"GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0008584///male gonad development+++GO:0007286///spermatid development+++GO:0016567///protein ubiquitination+++GO:0009566///fertilization","IPR006652///Kelch repeat type 1+++IPR030570///Kelch-like protein 32+++IPR011705///BTB/Kelch-associated+++IPR017096///BTB-kelch protein+++IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR015915///Kelch-type beta propeller","[KLH32_HUMAN|Reviewed]RecName: Full=Kelch-like protein 32; AltName: Full=BTB and kelch domain-containing protein 5;+++[A0A087WYQ8_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 32 {ECO:0000313|Ensembl:ENSP00000482012};+++[Q5THS9_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 32 {ECO:0000313|Ensembl:ENSP00000389310}; Flags: Fragment;+++[Q5THT1_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 32 {ECO:0000313|Ensembl:ENSP00000358258};+++[Q6IQ08_HUMAN|Unreviewed]SubName: Full=KLHL32 protein {ECO:0000313|EMBL:AAH71627.1};+++[Q8IXH0_HUMAN|Unreviewed]SubName: Full=KIAA1900, isoform CRA_a {ECO:0000313|EMBL:EAW48497.1}; SubName: Full=Kelch-like protein 32 {ECO:0000313|Ensembl:ENSP00000445453}; SubName: Full=UG0030H05 {ECO:0000313|EMBL:AAN76510.1};"]
[114818,"'KLHL29'",207,260,233.5,{"$nulls":4},"GO:0031463///Cul3-RING ubiquitin ligase complex",null,"GO:0016567///protein ubiquitination","IPR011333///SKP1/BTB/POZ domain superfamily+++IPR011705///BTB/Kelch-associated+++IPR015915///Kelch-type beta propeller+++IPR000210///BTB/POZ domain+++IPR006652///Kelch repeat type 1","[KLH29_HUMAN|Reviewed]RecName: Full=Kelch-like protein 29; AltName: Full=Kelch repeat and BTB domain-containing protein 9;+++[H0Y2P5_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 29 {ECO:0000313|Ensembl:ENSP00000288548}; Flags: Fragment;+++[Q6NT65_HUMAN|Unreviewed]SubName: Full=KLHL29 protein {ECO:0000313|EMBL:AAH69271.1}; Flags: Fragment;"]
[114900,"'C1QTNF4'",4,4,4,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0003674///molecular_function+++GO:0005125///cytokine activity","GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0010469///regulation of signaling receptor activity+++GO:2000778///positive regulation of interleukin-6 secretion+++GO:0070105///positive regulation of interleukin-6-mediated signaling pathway+++GO:1904469///positive regulation of tumor necrosis factor secretion+++GO:0032755///positive regulation of interleukin-6 production","IPR008983///Tumour necrosis factor-like domain superfamily+++IPR001073///C1q domain","[C1QT4_HUMAN|Reviewed]RecName: Full=Complement C1q tumor necrosis factor-related protein 4; Flags: Precursor;+++[E9PPZ5_HUMAN|Unreviewed]SubName: Full=Complement C1q tumor necrosis factor-related protein 4 {ECO:0000313|Ensembl:ENSP00000434548};"]
[115004,"'CGAS'",0,3,1.5,"04623///Cytosolic DNA-sensing pathway+++05163///Human cytomegalovirus infection","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,"R08701///tRNA uridine 5-carboxymethylaminomethyl modification tRNA containing 2-thiouridine + Glycine + Folinic acid + Reduced acceptor <=> tRNA containing 5-carboxymethylaminomethyl-2-thiouridine + Tetrahydrofolate + Acceptor + H2O","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0003682///chromatin binding+++GO:0003690///double-stranded DNA binding+++GO:0005524///ATP binding+++GO:0003677///DNA binding+++GO:0016779///nucleotidyltransferase activity+++GO:0005525///GTP binding+++GO:0061501///cyclic-GMP-AMP synthase activity+++GO:0005515///protein binding","GO:0050776///regulation of immune response+++GO:0032479///regulation of type I interferon production+++GO:0002230///positive regulation of defense response to virus by host+++GO:0045087///innate immune response+++GO:2000774///positive regulation of cellular senescence+++GO:0050863///regulation of T cell activation+++GO:0002637///regulation of immunoglobulin production+++GO:0002376///immune system process+++GO:0071360///cellular response to exogenous dsRNA+++GO:0006974///cellular response to DNA damage stimulus+++GO:0051607///defense response to virus+++GO:0008340///determination of adult lifespan+++GO:0038001///paracrine signaling+++GO:0002218///activation of innate immune response+++GO:0010753///positive regulation of cGMP-mediated signaling+++GO:0032481///positive regulation of type I interferon production+++GO:0043950///positive regulation of cAMP-mediated signaling","IPR024810///Mab-21 domain","[CGAS_HUMAN|Reviewed]RecName: Full=Cyclic GMP-AMP synthase {ECO:0000303|PubMed:23258413}; Short=cGAMP synthase {ECO:0000303|PubMed:23258413}; Short=cGAS {ECO:0000303|PubMed:23258413}; Short=h-cGAS {ECO:0000303|PubMed:23258413}; EC=2.7.7.86 {ECO:0000269|PubMed:23258413, ECO:0000269|PubMed:23707061, ECO:0000269|PubMed:23722159, ECO:0000269|PubMed:25131990}; AltName: Full=2'3'-cGAMP synthase {ECO:0000303|PubMed:23258413}; AltName: Full=Mab-21 domain-containing protein 1;"]
[1153,"'CIRBP'",749,709,729,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005681///spliceosomal complex+++GO:1990904///ribonucleoprotein complex+++GO:0005654///nucleoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0005737///cytoplasm","GO:0003730///mRNA 3'-UTR binding+++GO:0008266///poly(U) RNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0070181///small ribosomal subunit rRNA binding+++GO:0030371///translation repressor activity+++GO:0003676///nucleic acid binding","GO:0034063///stress granule assembly+++GO:0017148///negative regulation of translation+++GO:0009409///response to cold+++GO:0009411///response to UV+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0045727///positive regulation of translation+++GO:0048255///mRNA stabilization","IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR003954///RNA recognition motif domain, eukaryote+++IPR035979///RNA-binding domain superfamily+++IPR034278///RBM3/CIRBP, RNA recognition motif","[CIRBP_HUMAN|Reviewed]RecName: Full=Cold-inducible RNA-binding protein; AltName: Full=A18 hnRNP; AltName: Full=Glycine-rich RNA-binding protein CIRP;+++[D6W5Y5_HUMAN|Unreviewed]SubName: Full=Cold inducible RNA binding protein, isoform CRA_c {ECO:0000313|EMBL:EAW69524.1}; SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000465077};+++[F6WMK9_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000407512}; Flags: Fragment;+++[K7EIF7_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000464728};+++[K7EJV1_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000465334}; Flags: Fragment;+++[K7EJV5_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000465338}; Flags: Fragment;+++[K7ELL4_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000466131}; Flags: Fragment;+++[K7ELT6_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000466216};+++[K7ELV6_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000466238}; Flags: Fragment;+++[K7EMY9_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000466712};+++[K7ENN6_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000467028}; Flags: Fragment;+++[K7ENX8_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000467138}; Flags: Fragment;+++[K7EPM4_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000467449};+++[K7EQL0_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000467876};+++[K7EQR7_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000467948};+++[K7EQX4_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000468016}; Flags: Fragment;+++[K7ER40_HUMAN|Unreviewed]SubName: Full=Cold-inducible RNA-binding protein {ECO:0000313|Ensembl:ENSP00000468097}; Flags: Fragment;+++[Q53XX5_HUMAN|Unreviewed]SubName: Full=Cold inducible RNA binding protein {ECO:0000313|EMBL:AAP35874.1}; SubName: Full=Cold inducible RNA binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW69520.1}; SubName: Full=Testicular tissue protein Li 39 {ECO:0000313|EMBL:AEE60952.1};"]
[115701,"'ALPK2'",636,861,748.5,{"$nulls":4},"GO:0005737///cytoplasm","GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","IPR036179///Immunoglobulin-like domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR013098///Immunoglobulin I-set+++IPR003598///Immunoglobulin subtype 2+++IPR011009///Protein kinase-like domain superfamily+++IPR003599///Immunoglobulin subtype+++IPR004166///MHCK/EF2 kinase+++IPR013783///Immunoglobulin-like fold","[ALPK2_HUMAN|Reviewed]RecName: Full=Alpha-protein kinase 2; EC=2.7.11.-; AltName: Full=Heart alpha-protein kinase;"]
[115992,"'RNF166'",365,356,360.5,{"$nulls":4},"GO:0005622///intracellular","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0000209///protein polyubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process","IPR027370///RING-type zinc-finger, LisH dimerisation motif+++IPR017907///Zinc finger, RING-type, conserved site+++IPR001841///Zinc finger, RING-type+++IPR008598///Drought induced 19 protein type, zinc-binding domain+++IPR034734///Zinc finger C2HC RNF-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type","[RN166_HUMAN|Reviewed]RecName: Full=RING finger protein 166;+++[H3BPZ9_HUMAN|Unreviewed]SubName: Full=RING finger protein 166 {ECO:0000313|Ensembl:ENSP00000455539}; Flags: Fragment;+++[H3BQ58_HUMAN|Unreviewed]SubName: Full=RING finger protein 166 {ECO:0000313|Ensembl:ENSP00000455617}; Flags: Fragment;+++[H3BTX7_HUMAN|Unreviewed]SubName: Full=RING finger protein 166 {ECO:0000313|Ensembl:ENSP00000457374};"]
[116150,"'NUS1'",454,649,551.5,"01110///Biosynthesis of secondary metabolites+++00900///Terpenoid backbone biosynthesis","H00118///Congenital disorders of glycosylation (CDG) type I",null,"R05556///(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10-55 isopentenyl units)   trans,trans-Farnesyl diphosphate + n Isopentenyl diphosphate <=> Dehydrodolichol diphosphate + n Diphosphate","GO:0005783///endoplasmic reticulum+++GO:1904423///dehydrodolichyl diphosphate synthase complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016765///transferase activity, transferring alkyl or aryl (other than methyl) groups+++GO:0004659///prenyltransferase activity+++GO:0016740///transferase activity+++GO:0045547///dehydrodolichyl diphosphate synthase activity+++GO:0005515///protein binding","GO:0055092///sterol homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0030154///cell differentiation+++GO:0035268///protein mannosylation+++GO:0006489///dolichyl diphosphate biosynthetic process+++GO:0019408///dolichol biosynthetic process+++GO:0001525///angiogenesis+++GO:0006486///protein glycosylation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0007275///multicellular organism development+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0032383///regulation of intracellular cholesterol transport","IPR038887///Dehydrodolichyl diphosphate synthase complex subunit Nus1+++IPR001441///Decaprenyl diphosphate synthase-like+++IPR036424///Decaprenyl diphosphate synthase-like superfamily","[NGBR_HUMAN|Reviewed]RecName: Full=Dehydrodolichyl diphosphate synthase complex subunit NUS1 {ECO:0000305}; EC=2.5.1.87 {ECO:0000269|PubMed:25066056, ECO:0000269|PubMed:28842490}; AltName: Full=Cis-prenyltransferase subunit NgBR {ECO:0000303|PubMed:28842490}; AltName: Full=Nogo-B receptor {ECO:0000303|PubMed:16835300}; Short=NgBR {ECO:0000303|PubMed:16835300, ECO:0000303|PubMed:28842490}; AltName: Full=Nuclear undecaprenyl pyrophosphate synthase 1 homolog {ECO:0000305};"]
[116372,"'LYPD1'",70,62,66,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane","GO:0030550///acetylcholine receptor inhibitor activity+++GO:0033130///acetylcholine receptor binding","GO:0035094///response to nicotine+++GO:0095500///acetylcholine receptor signaling pathway+++GO:2000272///negative regulation of signaling receptor activity+++GO:0007271///synaptic transmission, cholinergic+++GO:1903077///negative regulation of protein localization to plasma membrane+++GO:0001662///behavioral fear response","IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR017452///GPCR, rhodopsin-like, 7TM","[LYPD1_HUMAN|Reviewed]RecName: Full=Ly6/PLAUR domain-containing protein 1; AltName: Full=Putative HeLa tumor suppressor; Short=PHTS; Flags: Precursor;+++[D3DP69_HUMAN|Unreviewed]SubName: Full=LY6/PLAUR domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAX11677.1};+++[F8WD77_HUMAN|Unreviewed]SubName: Full=Ly6/PLAUR domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000396651};+++[Q8IXM0_HUMAN|Unreviewed]SubName: Full=LYPDC1 protein {ECO:0000313|EMBL:AAH40046.1};"]
[116841,"'SNAP47'",504,413,458.5,{"$nulls":4},"GO:0098978///glutamatergic synapse+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0031083///BLOC-1 complex+++GO:0016020///membrane+++GO:0030672///synaptic vesicle membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0030425///dendrite+++GO:0005886///plasma membrane+++GO:0012505///endomembrane system+++GO:0031201///SNARE complex","GO:0019905///syntaxin binding+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding","GO:0099003///vesicle-mediated transport in synapse+++GO:0006887///exocytosis+++GO:0060291///long-term synaptic potentiation+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0098967///exocytic insertion of neurotransmitter receptor to postsynaptic membrane+++GO:0006906///vesicle fusion+++GO:0016082///synaptic vesicle priming","IPR000727///Target SNARE coiled-coil homology domain+++IPR011993///PH-like domain superfamily","[SNP47_HUMAN|Reviewed]RecName: Full=Synaptosomal-associated protein 47; Short=SNAP-47; AltName: Full=Epididymis luminal protein 170; AltName: Full=Synaptosomal-associated 47 kDa protein;+++[A0A087X0B7_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein 47 {ECO:0000313|Ensembl:ENSP00000483253};+++[A0A087X2J6_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein 47 {ECO:0000313|Ensembl:ENSP00000485027}; Flags: Fragment;+++[A0A0K0K1I8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 290 {ECO:0000313|EMBL:ACV87181.1}; Flags: Fragment;+++[H0Y627_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein 47 {ECO:0000313|Ensembl:ENSP00000402730}; Flags: Fragment;+++[H7C3C7_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein 47 {ECO:0000313|Ensembl:ENSP00000411128}; Flags: Fragment;+++[U3KPT7_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein 47 {ECO:0000313|Ensembl:ENSP00000475207}; Flags: Fragment;"]
[117166,"'WFIKKN1'",5,1,3,{"$nulls":4},"GO:0005576///extracellular region","GO:0050431///transforming growth factor beta binding+++GO:0004857///enzyme inhibitor activity+++GO:0005515///protein binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0048019///receptor antagonist activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity+++GO:0060021///roof of mouth development+++GO:0001501///skeletal system development+++GO:0043392///negative regulation of DNA binding+++GO:0048747///muscle fiber development+++GO:1900116///extracellular negative regulation of signal transduction+++GO:0032091///negative regulation of protein binding+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway","IPR036179///Immunoglobulin-like domain superfamily+++IPR033638///WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1+++IPR003599///Immunoglobulin subtype+++IPR008993///Tissue inhibitor of metalloproteinases-like, OB-fold+++IPR003598///Immunoglobulin subtype 2+++IPR036880///Pancreatic trypsin inhibitor Kunitz domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR036058///Kazal domain superfamily+++IPR002223///Pancreatic trypsin inhibitor Kunitz domain+++IPR001134///Netrin domain+++IPR002350///Kazal domain+++IPR013783///Immunoglobulin-like fold+++IPR020901///Proteinase inhibitor I2, Kunitz, conserved site+++IPR036645///Elafin-like superfamily+++IPR008197///WAP-type 'four-disulfide core' domain","[WFKN1_HUMAN|Reviewed]RecName: Full=WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1; AltName: Full=Growth and differentiation factor-associated serum protein 2; Short=GASP-2; Short=hGASP-2; AltName: Full=WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing protein; Flags: Precursor;"]
[117584,"'RFFL'",170,236,203,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0010008///endosome membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0055038///recycling endosome membrane+++GO:0005764///lysosome+++GO:0005886///plasma membrane+++GO:0002947///tumor necrosis factor receptor superfamily complex+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0002020///protease binding+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0002039///p53 binding+++GO:0061630///ubiquitin protein ligase activity","GO:0010804///negative regulation of tumor necrosis factor-mediated signaling pathway+++GO:0010762///regulation of fibroblast migration+++GO:0070936///protein K48-linked ubiquitination+++GO:0032006///regulation of TOR signaling+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0006915///apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1901797///negative regulation of signal transduction by p53 class mediator+++GO:2001271///negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis+++GO:1902042///negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","IPR001841///Zinc finger, RING-type+++IPR036361///SAP domain superfamily+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR011011///Zinc finger, FYVE/PHD-type","[RFFL_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase rififylin {ECO:0000305}; EC=2.3.2.27 {ECO:0000269|PubMed:15069192}; AltName: Full=Caspase regulator CARP2; AltName: Full=Caspases-8 and -10-associated RING finger protein 2; Short=CARP-2; AltName: Full=FYVE-RING finger protein Sakura; Short=Fring; AltName: Full=RING finger and FYVE-like domain-containing protein 1; AltName: Full=RING finger protein 189; AltName: Full=RING finger protein 34-like; AltName: Full=RING-type E3 ubiquitin transferase rififylin {ECO:0000305};+++[C9JE27_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase rififylin {ECO:0000313|Ensembl:ENSP00000395090}; Flags: Fragment;+++[J3KSI3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase rififylin {ECO:0000313|Ensembl:ENSP00000462499}; Flags: Fragment;+++[J3KSU7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase rififylin {ECO:0000313|Ensembl:ENSP00000462656}; Flags: Fragment;+++[J3QR17_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase rififylin {ECO:0000313|Ensembl:ENSP00000464000};"]
[118487,"'CHCHD1'",182,160,171,{"$nulls":4},"GO:0005829///cytosol+++GO:0001650///fibrillar center+++GO:0005840///ribosome+++GO:0005761///mitochondrial ribosome+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005743///mitochondrial inner membrane","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0032543///mitochondrial translation+++GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination","IPR010625///CHCH+++IPR009069///Cysteine alpha-hairpin motif superfamily+++IPR033620///Coiled-coil-helix-coiled-coil-helix domain-containing protein 1","[CHCH1_HUMAN|Reviewed]RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 1; AltName: Full=28S ribosomal protein S37, mitochondrial; Short=MRP-S37; AltName: Full=Mitochondrial small ribosomal subunit protein mS37 {ECO:0000303|PubMed:25838379}; AltName: Full=Nuclear protein C2360;+++[A6NJX6_HUMAN|Unreviewed]SubName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000361928};"]
[118924,"'FRA10AC1'",96,113,104.5,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding","GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","IPR019129///Folate-sensitive fragile site protein Fra10Ac1","[F10C1_HUMAN|Reviewed]RecName: Full=Protein FRA10AC1;+++[D3DR40_HUMAN|Unreviewed]SubName: Full=Chromosome 10 open reading frame 4, isoform CRA_b {ECO:0000313|EMBL:EAW50057.1};+++[L8E962_HUMAN|Unreviewed]SubName: Full=Alternative protein FRA10AC1 {ECO:0000313|EMBL:CCQ43845.1};"]
[119559,"'SFXN4'",102,91,96.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0015075///ion transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0055072///iron ion homeostasis+++GO:0006811///ion transport","IPR028825///Sideroflexin-4+++IPR004686///Tricarboxylate/iron carrier","[SFXN4_HUMAN|Reviewed]RecName: Full=Sideroflexin-4; AltName: Full=Breast cancer resistance marker 1;+++[B1AMV7_HUMAN|Unreviewed]SubName: Full=Sideroflexin-4 {ECO:0000313|Ensembl:ENSP00000358127}; Flags: Fragment;+++[B1AMV8_HUMAN|Unreviewed]SubName: Full=Sideroflexin-4 {ECO:0000313|Ensembl:ENSP00000414193}; Flags: Fragment;"]
[120227,"'CYP2R1'",67.81,55.8,61.805,"00100///Steroid biosynthesis+++01100///Metabolic pathways","H01143///Vitamin D-dependent rickets","M00103///Cholecalciferol biosynthesis","R03611///calciol,NADPH-hemoprotein reductase:oxygen oxidoreductase (25-hydroxylating)   Calcidiol + [Oxidized NADPH---hemoprotein reductase] + H2O <=> Vitamin D3 + [Reduced NADPH---hemoprotein reductase] + Oxygen","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0031090///organelle membrane","GO:0016491///oxidoreductase activity+++GO:0020037///heme binding+++GO:0008395///steroid hydroxylase activity+++GO:0046872///metal ion binding+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0030343///vitamin D3 25-hydroxylase activity+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0004497///monooxygenase activity+++GO:0005506///iron ion binding","GO:0006805///xenobiotic metabolic process+++GO:0010212///response to ionizing radiation+++GO:0006082///organic acid metabolic process+++GO:0042359///vitamin D metabolic process+++GO:0036378///calcitriol biosynthetic process from calciol+++GO:0010038///response to metal ion+++GO:0055114///oxidation-reduction process+++GO:0042738///exogenous drug catabolic process+++GO:0006766///vitamin metabolic process+++GO:0010164///response to cesium ion","IPR001128///Cytochrome P450+++IPR002401///Cytochrome P450, E-class, group I+++IPR036396///Cytochrome P450 superfamily+++IPR017972///Cytochrome P450, conserved site","[CP2R1_HUMAN|Reviewed]RecName: Full=Vitamin D 25-hydroxylase; EC=1.14.14.24 {ECO:0000269|PubMed:12867411, ECO:0000269|PubMed:15465040, ECO:0000269|PubMed:18511070}; AltName: Full=Cytochrome P450 2R1;+++[E9PJT9_HUMAN|Unreviewed]SubName: Full=Vitamin D 25-hydroxylase {ECO:0000313|Ensembl:ENSP00000435484};+++[E9PS56_HUMAN|Unreviewed]SubName: Full=Vitamin D 25-hydroxylase {ECO:0000313|Ensembl:ENSP00000432087};+++[K7EMQ4_HUMAN|Unreviewed]SubName: Full=Vitamin D 25-hydroxylase {ECO:0000313|Ensembl:ENSP00000466604}; Flags: Fragment;"]
[121256,"'TMEM132D'",30,26,28,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0010923///negative regulation of phosphatase activity","IPR026307///Transmembrane protein 132+++IPR031437///Transmembrane protein family 132, middle domain+++IPR031435///Transmembrane protein TMEM132, N-terminal+++IPR031436///Transmembrane protein TMEM132, C-terminal","[T132D_HUMAN|Reviewed]RecName: Full=Transmembrane protein 132D; AltName: Full=Mature oligodendrocytes transmembrane protein; Short=Mature OL transmembrane protein; Flags: Precursor;"]
[121643,"'FOXN4'",2,0,1,null,"H01181///T-cell immunodeficiency congenital alopecia and nail dystrophy (TIDAND)+++H00091///T-B+Severe combined immunodeficiencies (SCIDs)",null,null,"GO:0005634///nucleus","GO:0001158///enhancer sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007399///nervous system development+++GO:0001947///heart looping+++GO:0010842///retina layer formation+++GO:0030154///cell differentiation+++GO:0060579///ventral spinal cord interneuron fate commitment+++GO:0036302///atrioventricular canal development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0008016///regulation of heart contraction+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0048663///neuron fate commitment+++GO:0035881///amacrine cell differentiation","IPR036390///Winged helix DNA-binding domain superfamily+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR030456///Fork head domain conserved site 2+++IPR001766///Fork head domain","[FOXN4_HUMAN|Reviewed]RecName: Full=Forkhead box protein N4;+++[A0A0C4DG65_HUMAN|Unreviewed]SubName: Full=Forkhead box protein N4 {ECO:0000313|Ensembl:ENSP00000408085}; Flags: Fragment;+++[A4FUA3_HUMAN|Unreviewed]SubName: Full=FOXN4 protein {ECO:0000313|EMBL:AAI13074.1}; Flags: Fragment;+++[A6H901_HUMAN|Unreviewed]SubName: Full=FOXN4 protein {ECO:0000313|EMBL:AAI46826.1};+++[S4R3U5_HUMAN|Unreviewed]SubName: Full=Forkhead box protein N4 {ECO:0000313|Ensembl:ENSP00000474754}; Flags: Fragment;"]
[122786,"'FRMD6'",2555,3857,3206,"04392///Hippo signaling pathway - multiple species+++04390///Hippo signaling pathway",null,"M00683///Hippo signaling",null,"GO:0043296///apical junction complex+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0034613///cellular protein localization+++GO:0031032///actomyosin structure organization+++GO:0003383///apical constriction+++GO:0032970///regulation of actin filament-based process","IPR018979///FERM, N-terminal+++IPR035963///FERM superfamily, second domain+++IPR000299///FERM domain+++IPR018980///FERM, C-terminal PH-like domain+++IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR011993///PH-like domain superfamily+++IPR029071///Ubiquitin-like domain superfamily+++IPR019749///Band 4.1 domain+++IPR019748///FERM central domain","[FRMD6_HUMAN|Reviewed]RecName: Full=FERM domain-containing protein 6; AltName: Full=Willin;+++[G3V2L4_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000450735}; Flags: Fragment;+++[G3V3V8_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000451453}; Flags: Fragment;+++[G3V4T7_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000451977};+++[G3V517_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000452122}; Flags: Fragment;+++[H0YJ19_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000450667}; Flags: Fragment;+++[H0YJC1_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000451157}; Flags: Fragment;"]
[123207,"'C15orf40'",99,86.01,92.505,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"IPR036591///YggU-like superfamily+++IPR003746///Protein of unknown function DUF167","[CO040_HUMAN|Reviewed]RecName: Full=UPF0235 protein C15orf40;+++[A0A0S2Z5W1_HUMAN|Unreviewed]SubName: Full=Chromosome 15 open reading frame 40 isoform 3 {ECO:0000313|EMBL:ALQ34314.1};+++[A0A0S2Z6M2_HUMAN|Unreviewed]SubName: Full=Chromosome 15 open reading frame 40 isoform 1 {ECO:0000313|EMBL:ALQ34313.1}; Flags: Fragment;+++[H0Y996_HUMAN|Unreviewed]SubName: Full=UPF0235 protein C15orf40 {ECO:0000313|Ensembl:ENSP00000423436}; Flags: Fragment;+++[H0Y9H8_HUMAN|Unreviewed]SubName: Full=UPF0235 protein C15orf40 {ECO:0000313|Ensembl:ENSP00000424167}; Flags: Fragment;+++[H0YAC3_HUMAN|Unreviewed]SubName: Full=UPF0235 protein C15orf40 {ECO:0000313|Ensembl:ENSP00000426639}; Flags: Fragment;+++[H3BM85_HUMAN|Unreviewed]SubName: Full=UPF0235 protein C15orf40 {ECO:0000313|Ensembl:ENSP00000454276}; Flags: Fragment;+++[H3BMR1_HUMAN|Unreviewed]SubName: Full=UPF0235 protein C15orf40 {ECO:0000313|Ensembl:ENSP00000454502}; Flags: Fragment;+++[H3BQZ5_HUMAN|Unreviewed]SubName: Full=UPF0235 protein C15orf40 {ECO:0000313|Ensembl:ENSP00000456006};"]
[1238,"'ACKR2'",6,6,6,"04137///Mitophagy - animal+++04140///Autophagy - animal+++03320///PPAR signaling pathway+++00120///Primary bile acid biosynthesis+++01100///Metabolic pathways",null,"M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R04826///7alpha-hydroxycholest-4-en-3-one,ferrocytochrome-b5:oxygen oxidoreductase (12alpha-hydroxylating) 7alpha-Hydroxycholest-4-en-3-one + 2 H+ + Oxygen + 2 Ferrocytochrome b5 <=> 4-Cholesten-7alpha,12alpha-diol-3-one + 2 Ferricytochrome b5 + H2O","GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm+++GO:0005884///actin filament+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0009897///external side of plasma membrane+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0055037///recycling endosome","GO:0019956///chemokine binding+++GO:0005044///scavenger receptor activity+++GO:0016493///C-C chemokine receptor activity+++GO:0004950///chemokine receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0019957///C-C chemokine binding","GO:0060326///cell chemotaxis+++GO:0006898///receptor-mediated endocytosis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006968///cellular defense response+++GO:0007165///signal transduction+++GO:0002305///CD8-positive, gamma-delta intraepithelial T cell differentiation+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0007275///multicellular organism development+++GO:0006935///chemotaxis+++GO:0070098///chemokine-mediated signaling pathway+++GO:0006955///immune response+++GO:0019722///calcium-mediated signaling+++GO:0006954///inflammatory response","IPR017452///GPCR, rhodopsin-like, 7TM+++IPR001277///CXC chemokine receptor 4/atypical chemokine receptor 2+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR033037///Atypical chemokine receptor 2+++IPR000355///Chemokine receptor family","[ACKR2_HUMAN|Reviewed]RecName: Full=Atypical chemokine receptor 2; AltName: Full=C-C chemokine receptor D6; AltName: Full=Chemokine receptor CCR-10; AltName: Full=Chemokine receptor CCR-9; AltName: Full=Chemokine-binding protein 2; AltName: Full=Chemokine-binding protein D6;+++[A0A024R2X7_HUMAN|Unreviewed]SubName: Full=Chemokine binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW64679.1};+++[V9GYB7_HUMAN|Unreviewed]SubName: Full=Atypical chemokine receptor 2 {ECO:0000313|Ensembl:ENSP00000476581}; Flags: Fragment;+++[V9GYM0_HUMAN|Unreviewed]SubName: Full=Atypical chemokine receptor 2 {ECO:0000313|Ensembl:ENSP00000476901}; Flags: Fragment;+++[V9GYX0_HUMAN|Unreviewed]SubName: Full=Atypical chemokine receptor 2 {ECO:0000313|Ensembl:ENSP00000477157}; Flags: Fragment;+++[V9GZ70_HUMAN|Unreviewed]SubName: Full=Atypical chemokine receptor 2 {ECO:0000313|Ensembl:ENSP00000477475}; Flags: Fragment;"]
[124245,"'ZC3H18'",1258,1273,1265.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex+++GO:0016607///nuclear speck","GO:0046872///metal ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0000982///transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005507///copper ion binding","GO:0006351///transcription, DNA-templated","IPR000571///Zinc finger, CCCH-type+++IPR036855///Zinc finger, CCCH-type superfamily","[ZCH18_HUMAN|Reviewed]RecName: Full=Zinc finger CCCH domain-containing protein 18; AltName: Full=Nuclear protein NHN1;+++[B3KRL4_HUMAN|Unreviewed]SubName: Full=Conserved nuclear protein NHN1, isoform CRA_b {ECO:0000313|EMBL:EAW66800.1}; SubName: Full=cDNA FLJ34530 fis, clone HLUNG2008153, highly similar to Homo sapiens conserved nuclear protein NHN1 (NHN1), mRNA {ECO:0000313|EMBL:BAG52426.1}; SubName: Full=cDNA FLJ36075 fis, clone TESTI2019729, highly similar to Homo sapiens conserved nuclear protein NHN1 (NHN1), mRNA {ECO:0000313|EMBL:BAG52705.1};+++[B4DTK7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61387, highly similar to Homo sapiens conserved nuclear protein NHN1 (NHN1), mRNA {ECO:0000313|EMBL:BAG62019.1};+++[E7ERS3_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000416951};+++[H3BP01_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000455083}; Flags: Fragment;+++[H3BPD0_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000455260}; Flags: Fragment;+++[H3BRH3_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000456241}; Flags: Fragment;+++[H3BRN6_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 18 {ECO:0000313|Ensembl:ENSP00000456334}; Flags: Fragment;"]
[124641,"'OVCA2'",846.26,754.64,800.45,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016787///hydrolase activity","GO:0032526///response to retinoic acid","IPR029058///Alpha/Beta hydrolase fold+++IPR005645///Serine hydrolase FSH","[OVCA2_HUMAN|Reviewed]RecName: Full=Esterase OVCA2; EC=3.1.2.- {ECO:0000305}; AltName: Full=Ovarian cancer-associated gene 2 protein;"]
[124975,"'GGT6'",2,0.98,1.49,"00430///Taurine and hypotaurine metabolism+++01100///Metabolic pathways+++00460///Cyanoamino acid metabolism+++00480///Glutathione metabolism",null,null,"R01687///(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase   (5-L-Glutamyl)-peptide + Taurine <=> Peptide + 5-L-Glutamyl-taurine+++R03971///gamma-glutamyl-beta-aminopropiononitrile amidohydrolase   3-Aminopropiononitrile + L-Glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O+++R00494///glutathione gamma-glutamylaminopeptidase   Glutathione + H2O <=> Cys-Gly + L-Glutamate+++R03867///(5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase   Leukotriene C4 + Amino acid <=> Leukotriene D4 + 5-L-Glutamyl amino acid+++R01262///glutathione:L-amino-acid 5-glutamyltransferase   Glutathione + L-Amino acid <=> Cys-Gly + (5-L-Glutamyl)-L-amino acid+++R03970///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase   3-Cyano-L-alanine + L-Glutamate <=> gamma-Glutamyl-beta-cyanoalanine + H2O+++R04935///(5-L-glutamyl)-peptide:Se-Methylselenocysteine 5-glutamyltransferase   (5-L-Glutamyl)-peptide + Se-Methyl-L-selenocysteine <=> Peptide + gamma-Glutamyl-Se-methylselenocysteine+++R03916///(5-glutamyl)-peptide:amino-acid 5-glutamyltransferase   R-S-Glutathione + H2O <=> R-S-Cysteinylglycine + L-Glutamate","GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0036374///glutathione hydrolase activity+++GO:0102953///hypoglycin A gamma-glutamyl transpeptidase activity+++GO:0003674///molecular_function+++GO:0016746///transferase activity, transferring acyl groups+++GO:0103068///leukotriene C4 gamma-glutamyl transferase activity+++GO:0016787///hydrolase activity+++GO:0016740///transferase activity","GO:0006750///glutathione biosynthetic process+++GO:0006749///glutathione metabolic process+++GO:0006508///proteolysis+++GO:1901750///leukotriene D4 biosynthetic process+++GO:0006751///glutathione catabolic process+++GO:0008150///biological_process","IPR000101///Gamma-glutamyltranspeptidase+++IPR029055///Nucleophile aminohydrolases, N-terminal","[GGT6_HUMAN|Reviewed]RecName: Full=Glutathione hydrolase 6; EC=3.4.19.13; AltName: Full=Gamma-glutamyltransferase 6; Short=GGT 6; EC=2.3.2.2; AltName: Full=Gamma-glutamyltranspeptidase 6; Contains: RecName: Full=Glutathione hydrolase 6 heavy chain; Contains: RecName: Full=Glutathione hydrolase 6 light chain; Flags: Precursor;+++[B4DKN3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50980 {ECO:0000313|EMBL:BAG59245.1};+++[B4DPG6_HUMAN|Unreviewed]SubName: Full=Glutathione hydrolase 6 {ECO:0000313|Ensembl:ENSP00000461230}; SubName: Full=cDNA FLJ51026 {ECO:0000313|EMBL:BAG60578.1};+++[I3L2G6_HUMAN|Unreviewed]SubName: Full=Glutathione hydrolase 6 {ECO:0000313|Ensembl:ENSP00000459662}; Flags: Fragment;+++[J3KPJ0_HUMAN|Unreviewed]SubName: Full=Glutathione hydrolase 6 {ECO:0000313|Ensembl:ENSP00000370962};+++[Q6ZPD7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ25990 fis, clone DMC02673 {ECO:0000313|EMBL:BAC85168.1};"]
[125893,"'ZNF816'",36.26,52.52,44.39,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box","[ZN816_HUMAN|Reviewed]RecName: Full=Zinc finger protein 816;+++[A0A024R4J0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW72107.1};+++[F5GXJ3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 816 {ECO:0000313|Ensembl:ENSP00000333199}; Flags: Fragment;+++[I3L0H5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 816 {ECO:0000313|Ensembl:ENSP00000408965}; Flags: Fragment;+++[M0QY99_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 816 {ECO:0000313|Ensembl:ENSP00000469688};+++[M0QZX7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 816 {ECO:0000313|Ensembl:ENSP00000470838};+++[M0R0G1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 816 {ECO:0000313|Ensembl:ENSP00000471215};"]
[1261,"'CNGA3'",4,5,4.5,"04740///Olfactory transduction+++04024///cAMP signaling pathway","H00971///Achromatopsia",null,null,"GO:0016021///integral component of membrane+++GO:0043194///axon initial segment+++GO:0030425///dendrite+++GO:0005737///cytoplasm+++GO:0043204///perikaryon+++GO:1902495///transmembrane transporter complex+++GO:0097386///glial cell projection+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0043025///neuronal cell body","GO:0030553///cGMP binding+++GO:0000166///nucleotide binding+++GO:0005223///intracellular cGMP-activated cation channel activity+++GO:0015276///ligand-gated ion channel activity+++GO:0008022///protein C-terminus binding+++GO:0005222///intracellular cAMP-activated cation channel activity+++GO:0005216///ion channel activity","GO:0034220///ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0098659///inorganic cation import across plasma membrane+++GO:0051591///response to cAMP+++GO:0031960///response to corticosteroid+++GO:0007165///signal transduction+++GO:0032026///response to magnesium ion+++GO:0006811///ion transport+++GO:0007601///visual perception+++GO:0006812///cation transport+++GO:0050896///response to stimulus","IPR005821///Ion transport domain+++IPR032406///Cyclic nucleotide-gated channel, C-terminal leucine zipper domain+++IPR018488///Cyclic nucleotide-binding, conserved site+++IPR018490///Cyclic nucleotide-binding-like+++IPR014710///RmlC-like jelly roll fold+++IPR000595///Cyclic nucleotide-binding domain","[CNGA3_HUMAN|Reviewed]RecName: Full=Cyclic nucleotide-gated cation channel alpha-3; AltName: Full=Cone photoreceptor cGMP-gated channel subunit alpha; AltName: Full=Cyclic nucleotide-gated channel alpha-3; Short=CNG channel alpha-3; Short=CNG-3; Short=CNG3;+++[A0A097I4X7_HUMAN|Unreviewed]SubName: Full=Cyclic nucleotide-gated cation channel alpha-3 {ECO:0000313|EMBL:AIT55915.1}; Flags: Fragment;+++[L8E7M2_HUMAN|Unreviewed]SubName: Full=Alternative protein CNGA3 {ECO:0000313|EMBL:CCQ43134.1};"]
[1263,"'PLK3'",1384,1227,1305.5,"04625///C-type lectin receptor signaling pathway+++05152///Tuberculosis+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005795///Golgi stack+++GO:0005730///nucleolus+++GO:0043025///neuronal cell body+++GO:0005856///cytoskeleton+++GO:0030425///dendrite+++GO:0005794///Golgi apparatus+++GO:0005813///centrosome","GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0002039///p53 binding+++GO:0016301///kinase activity","GO:0032465///regulation of cytokinesis+++GO:2000777///positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia+++GO:0090316///positive regulation of intracellular protein transport+++GO:0090166///Golgi disassembly+++GO:0009314///response to radiation+++GO:0043066///negative regulation of apoptotic process+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:1904716///positive regulation of chaperone-mediated autophagy+++GO:0051302///regulation of cell division+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0006468///protein phosphorylation+++GO:0000302///response to reactive oxygen species+++GO:0043491///protein kinase B signaling+++GO:0044819///mitotic G1/S transition checkpoint+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007113///endomitotic cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031122///cytoplasmic microtubule organization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0006970///response to osmotic stress+++GO:0006915///apoptotic process+++GO:0007049///cell cycle","IPR008271///Serine/threonine-protein kinase, active site+++IPR020658///Serine/threonine-protein kinase Plk3+++IPR036947///POLO box domain superfamily+++IPR000959///POLO box domain+++IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain+++IPR033695///Second polo-box domain+++IPR033701///First polo-box domain+++IPR017441///Protein kinase, ATP binding site","[PLK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PLK3; EC=2.7.11.21; AltName: Full=Cytokine-inducible serine/threonine-protein kinase; AltName: Full=FGF-inducible kinase; AltName: Full=Polo-like kinase 3; Short=PLK-3; AltName: Full=Proliferation-related kinase;"]
[126306,"'JSRP1'",14,7,10.5,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016529///sarcoplasmic reticulum+++GO:0016020///membrane",null,"GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0003009///skeletal muscle contraction","IPR026178///Junctional sarcoplasmic reticulum protein 1","[JSPR1_HUMAN|Reviewed]RecName: Full=Junctional sarcoplasmic reticulum protein 1; AltName: Full=Junctional-face membrane protein of 45 kDa homolog; Short=JP-45;"]
[126526,"'C19orf47'",340.43,314.8,327.615,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR039161///Uncharacterized protein C19orf47-like","[CS047_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C19orf47;+++[A0A2R8Y6U9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000495586}; Flags: Fragment;+++[J3QKY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000463294};+++[J3QKZ5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000463305}; Flags: Fragment;+++[J3QS16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000464478}; Flags: Fragment;+++[J3QS80_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000464567}; Flags: Fragment;+++[J9JIE4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C19orf47 {ECO:0000313|Ensembl:ENSP00000350556}; Flags: Fragment;"]
[1268,"'CNR1'",4,2,3,"04080///Neuroactive ligand-receptor interaction+++04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++04015///Rap1 signaling pathway",{"$nulls":3},"GO:0032592///integral component of mitochondrial membrane+++GO:0005886///plasma membrane+++GO:0005741///mitochondrial outer membrane+++GO:0098982///GABA-ergic synapse+++GO:0030426///growth cone+++GO:0005887///integral component of plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0045121///membrane raft+++GO:0099056///integral component of presynaptic membrane","GO:0008144///drug binding+++GO:0004949///cannabinoid receptor activity","GO:0099553///trans-synaptic signaling by endocannabinoid, modulating synaptic transmission+++GO:0007413///axonal fasciculation+++GO:0060405///regulation of penile erection+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0050796///regulation of insulin secretion+++GO:0060135///maternal process involved in female pregnancy+++GO:0007613///memory+++GO:0007283///spermatogenesis+++GO:0045471///response to ethanol+++GO:0045776///negative regulation of blood pressure+++GO:0098921///retrograde trans-synaptic signaling by endocannabinoid+++GO:0038171///cannabinoid signaling pathway+++GO:0042593///glucose homeostasis+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0045759///negative regulation of action potential+++GO:0033602///negative regulation of dopamine secretion+++GO:0010976///positive regulation of neuron projection development+++GO:0002866///positive regulation of acute inflammatory response to antigenic stimulus+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0031622///positive regulation of fever generation+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0035094///response to nicotine+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0043065///positive regulation of apoptotic process+++GO:0043278///response to morphine+++GO:0045777///positive regulation of blood pressure+++GO:0060259///regulation of feeding behavior+++GO:0032496///response to lipopolysaccharide+++GO:0042220///response to cocaine+++GO:0019233///sensory perception of pain+++GO:0007584///response to nutrient+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007568///aging+++GO:0033004///negative regulation of mast cell activation","IPR002230///Cannabinoid receptor family+++IPR017452///GPCR, rhodopsin-like, 7TM+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR000810///Cannabinoid receptor type 1","[CNR1_HUMAN|Reviewed]RecName: Full=Cannabinoid receptor 1; Short=CB-R; Short=CB1; AltName: Full=CANN6;+++[S5TLS4_HUMAN|Unreviewed]RecName: Full=Cannabinoid receptor 1 {ECO:0000256|PIRNR:PIRNR037995};+++[V5KA96_HUMAN|Unreviewed]RecName: Full=Cannabinoid receptor 1 {ECO:0000256|PIRNR:PIRNR037995};"]
[127262,"'TPRG1L'",2060,1753,1906.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0008021///synaptic vesicle+++GO:0044305///calyx of Held+++GO:0030672///synaptic vesicle membrane+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0003674///molecular_function","GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0008150///biological_process","IPR022158///Inositol phosphatase+++IPR034753///hSac2 domain","[TPRGL_HUMAN|Reviewed]RecName: Full=Tumor protein p63-regulated gene 1-like protein {ECO:0000305}; AltName: Full=Mossy fiber terminal-associated vertebrate-specific presynaptic protein; AltName: Full=Protein FAM79A;"]
[127700,"'OSCP1'",128,92,110,{"$nulls":4},"GO:0016020///membrane+++GO:0009925///basal plasma membrane+++GO:0005886///plasma membrane",null,null,"IPR019332///Organic solute carrier protein 1","[OSCP1_HUMAN|Reviewed]RecName: Full=Protein OSCP1; Short=hOSCP1; AltName: Full=Organic solute transport protein 1; AltName: Full=Oxidored-nitro domain-containing protein 1;+++[C9JF58_HUMAN|Unreviewed]SubName: Full=Protein OSCP1 {ECO:0000313|Ensembl:ENSP00000390820};+++[H0YAG0_HUMAN|Unreviewed]SubName: Full=Protein OSCP1 {ECO:0000313|Ensembl:ENSP00000426981}; Flags: Fragment;+++[H0YDT3_HUMAN|Unreviewed]SubName: Full=Protein OSCP1 {ECO:0000313|Ensembl:ENSP00000434268}; Flags: Fragment;+++[H7C0S2_HUMAN|Unreviewed]SubName: Full=Protein OSCP1 {ECO:0000313|Ensembl:ENSP00000396417}; Flags: Fragment;"]
[128153,"'SPATA17'",6,2,4,{"$nulls":4},"GO:0005575///cellular_component+++GO:0005737///cytoplasm","GO:0003674///molecular_function+++GO:0005516///calmodulin binding","GO:0008150///biological_process","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR000048///IQ motif, EF-hand binding site","[SPT17_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 17;+++[B4E2J4_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein H {ECO:0000313|Ensembl:ENSP00000441306}; SubName: Full=cDNA FLJ57443 {ECO:0000313|EMBL:BAG65156.1};+++[D6RGG0_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein H {ECO:0000313|Ensembl:ENSP00000421223};+++[H0YMU5_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein H {ECO:0000313|Ensembl:ENSP00000453749};+++[H3BMH8_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein H {ECO:0000313|Ensembl:ENSP00000454387}; Flags: Fragment;+++[H3BRL4_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein H {ECO:0000313|Ensembl:ENSP00000456293}; Flags: Fragment;+++[H3BU17_HUMAN|Unreviewed]SubName: Full=IQ domain-containing protein H {ECO:0000313|Ensembl:ENSP00000457425}; Flags: Fragment;+++[L8E948_HUMAN|Unreviewed]SubName: Full=Alternative protein IQCH {ECO:0000313|EMBL:CCQ43694.1};+++[R4GN71_HUMAN|Unreviewed]SubName: Full=Spermatogenesis-associated protein 17 {ECO:0000313|Ensembl:ENSP00000473514};"]
[128434,"'VSTM2L'",2132,2188,2160,{"$nulls":4},"GO:0030424///axon+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0098632///cell-cell adhesion mediator activity+++GO:0005515///protein binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0070593///dendrite self-avoidance+++GO:0007411///axon guidance+++GO:0043524///negative regulation of neuron apoptotic process","IPR007110///Immunoglobulin-like domain+++IPR013783///Immunoglobulin-like fold+++IPR027115///V-set and transmembrane domain-containing protein 2-like protein+++IPR013106///Immunoglobulin V-set domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003599///Immunoglobulin subtype","[VTM2L_HUMAN|Reviewed]RecName: Full=V-set and transmembrane domain-containing protein 2-like protein; Flags: Precursor;"]
[1289,"'COL5A1'",12706,23824,18265,"04974///Protein digestion and absorption","H00519///Type XI collagenopathies+++H02079///Oto-spondylo-megaepiphyseal dysplasia+++H00802///Ehlers-Danlos syndrome (EDS)+++H02080///Fibrochondrogenesis+++H00605///Deafness, autosomal recessive+++H02072///Stickler syndrome+++H00431///Ossification of the posterior longitudinal ligament of spine (OPLL)+++H00604///Deafness, autosomal dominant+++H00805///Vitreoretinal degeneration+++H02081///Marshall syndrome",null,null,"GO:0031012///extracellular matrix+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0005588///collagen type V trimer+++GO:0005604///basement membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region","GO:0043394///proteoglycan binding+++GO:0030020///extracellular matrix structural constituent conferring tensile strength+++GO:0005515///protein binding+++GO:0048407///platelet-derived growth factor binding+++GO:0005178///integrin binding+++GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0046872///metal ion binding","GO:0048592///eye morphogenesis+++GO:1903225///negative regulation of endodermal cell differentiation+++GO:0032964///collagen biosynthetic process+++GO:0043588///skin development+++GO:0097435///supramolecular fiber organization+++GO:0051128///regulation of cellular component organization+++GO:0035989///tendon development+++GO:0016477///cell migration+++GO:0007155///cell adhesion+++GO:0030199///collagen fibril organization+++GO:0003007///heart morphogenesis+++GO:0045112///integrin biosynthetic process+++GO:0035313///wound healing, spreading of epidermal cells+++GO:0001568///blood vessel development+++GO:0030198///extracellular matrix organization","IPR008160///Collagen triple helix repeat+++IPR000885///Fibrillar collagen, C-terminal+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR001791///Laminin G domain","[CO5A1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(V) chain; Flags: Precursor;+++[A0A024R8E5_HUMAN|Unreviewed]SubName: Full=Collagen, type V, alpha 1, isoform CRA_a {ECO:0000313|EMBL:EAW88131.1};+++[B2ZZ86_HUMAN|Unreviewed]SubName: Full=Collagen type V alpha 1 {ECO:0000313|EMBL:BAG48312.1};+++[H7BY82_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(V) chain {ECO:0000313|Ensembl:ENSP00000360885}; Flags: Fragment;+++[L8E771_HUMAN|Unreviewed]SubName: Full=Alternative protein COL5A1 {ECO:0000313|EMBL:CCQ42964.1};+++[Q59EE7_HUMAN|Unreviewed]SubName: Full=Pro-alpha-1 type V collagen variant {ECO:0000313|EMBL:BAD93101.1}; Flags: Fragment;+++[Q9UML4_HUMAN|Unreviewed]SubName: Full=Alpha-1 type V collagen {ECO:0000313|EMBL:AAA79853.1}; Flags: Fragment;"]
[129446,"'XIRP2'",0,6,3,{"$nulls":4},"GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0030018///Z disc+++GO:0030054///cell junction","GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0051393///alpha-actinin binding","GO:0045216///cell-cell junction organization+++GO:0003281///ventricular septum development+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0008150///biological_process+++GO:0007507///heart development","IPR030107///Xin actin-binding repeat-containing protein 2+++IPR030072///Xin actin-binding repeat-containing protein 1/2+++IPR012510///Actin-binding, Xin repeat","[XIRP2_HUMAN|Reviewed]RecName: Full=Xin actin-binding repeat-containing protein 2; AltName: Full=Beta-xin; AltName: Full=Cardiomyopathy-associated protein 3; AltName: Full=Xeplin;+++[A0A0A0MQZ3_HUMAN|Unreviewed]SubName: Full=Xin actin-binding repeat-containing protein 2 {ECO:0000313|Ensembl:ENSP00000295237};"]
[129881,"'CCDC173'",2,1,1.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":6},"IPR039986///Coiled-coil domain-containing protein 173","[CC173_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 173;+++[B4DX81_HUMAN|Unreviewed]SubName: Full=HCG15219, isoform CRA_b {ECO:0000313|EMBL:EAX11265.1}; SubName: Full=cDNA FLJ59063 {ECO:0000313|EMBL:BAG63293.1};+++[C9J9F8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 173 {ECO:0000313|Ensembl:ENSP00000405608}; Flags: Fragment;+++[C9JQ25_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 173 {ECO:0000313|Ensembl:ENSP00000408143}; Flags: Fragment;"]
[130497,"'OSR1'",341,151,246,{"$nulls":4},"GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0005634///nucleus","GO:0004674///protein serine/threonine kinase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0019901///protein kinase binding","GO:0008406///gonad development+++GO:0030154///cell differentiation+++GO:0072207///metanephric epithelium development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2000543///positive regulation of gastrulation+++GO:0048863///stem cell differentiation+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:0072234///metanephric nephron tubule development+++GO:0048793///pronephros development+++GO:0007507///heart development+++GO:0048389///intermediate mesoderm development+++GO:0072168///specification of anterior mesonephric tubule identity+++GO:0072184///renal vesicle progenitor cell differentiation+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0042474///middle ear morphogenesis+++GO:0072166///posterior mesonephric tubule development+++GO:0072183///negative regulation of nephron tubule epithelial cell differentiation+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0043066///negative regulation of apoptotic process+++GO:0030501///positive regulation of bone mineralization+++GO:0072143///mesangial cell development+++GO:0072180///mesonephric duct morphogenesis+++GO:0001823///mesonephros development+++GO:0042733///embryonic digit morphogenesis+++GO:0072190///ureter urothelium development+++GO:0072111///cell proliferation involved in kidney development+++GO:0060021///roof of mouth development+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0035115///embryonic forelimb morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:0072075///metanephric mesenchyme development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0090094///metanephric cap mesenchymal cell proliferation involved in metanephros development+++GO:0042476///odontogenesis+++GO:0071300///cellular response to retinoic acid+++GO:0072259///metanephric interstitial fibroblast development+++GO:0001655///urogenital system development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0002062///chondrocyte differentiation+++GO:0072498///embryonic skeletal joint development+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0072169///specification of posterior mesonephric tubule identity+++GO:0023016///signal transduction by trans-phosphorylation+++GO:0007231///osmosensory signaling pathway+++GO:0001657///ureteric bud development+++GO:0072268///pattern specification involved in metanephros development+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0006351///transcription, DNA-templated+++GO:0072208///metanephric smooth muscle tissue development+++GO:0035116///embryonic hindlimb morphogenesis","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[OSR1_HUMAN|Reviewed]RecName: Full=Protein odd-skipped-related 1;"]
[130752,"'MDH1B'",9,4,6.5,null,"H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005737///cytoplasm","GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0016491///oxidoreductase activity+++GO:0030060///L-malate dehydrogenase activity+++GO:0016615///malate dehydrogenase activity+++GO:0003824///catalytic activity","GO:0006734///NADH metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006108///malate metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006099///tricarboxylic acid cycle+++GO:0006107///oxaloacetate metabolic process","IPR036291///NAD(P)-binding domain superfamily+++IPR015955///Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal+++IPR010945///Malate dehydrogenase, type 2","[MDH1B_HUMAN|Reviewed]RecName: Full=Putative malate dehydrogenase 1B; EC=1.1.1.-;+++[B4DY40_HUMAN|Unreviewed]SubName: Full=Putative malate dehydrogenase 1B {ECO:0000313|Ensembl:ENSP00000403810}; SubName: Full=cDNA FLJ51389, highly similar to Homo sapiens malate dehydrogenase 1B, NAD (MDH1B), mRNA {ECO:0000313|EMBL:BAG63602.1};+++[C9JER5_HUMAN|Unreviewed]SubName: Full=Putative malate dehydrogenase 1B {ECO:0000313|Ensembl:ENSP00000416577};"]
[131368,"'ZPLD1'",74,93,83.5,{"$nulls":4},"GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle",null,null,"IPR001507///Zona pellucida domain","[ZPLD1_HUMAN|Reviewed]RecName: Full=Zona pellucida-like domain-containing protein 1; Short=ZP domain-containing protein 1; AltName: Full=Cupulin {ECO:0000250|UniProtKB:C0H9B6}; Contains: RecName: Full=Zona pellucida-like domain-containing protein 1, secreted form {ECO:0000250|UniProtKB:C0H9B6}; Flags: Precursor;"]
[1318,"'SLC31A2'",247,155,201,{"$nulls":4},"GO:0005770///late endosome+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0055037///recycling endosome+++GO:0005887///integral component of plasma membrane","GO:0005375///copper ion transmembrane transporter activity","GO:0006825///copper ion transport+++GO:0006811///ion transport+++GO:0006878///cellular copper ion homeostasis+++GO:0035434///copper ion transmembrane transport+++GO:1902311///regulation of copper ion transmembrane transport","IPR007274///Ctr copper transporter","[COPT2_HUMAN|Reviewed]RecName: Full=Probable low affinity copper uptake protein 2; AltName: Full=Copper transporter 2; Short=hCTR2; AltName: Full=Solute carrier family 31 member 2;+++[F2Z3D2_HUMAN|Unreviewed]SubName: Full=Probable low affinity copper uptake protein 2 {ECO:0000313|Ensembl:ENSP00000363337};+++[Q53X94_HUMAN|Unreviewed]SubName: Full=SLC31A2 protein {ECO:0000313|EMBL:CAG28543.1}; SubName: Full=Solute carrier family 31 (Copper transporters), member 2 {ECO:0000313|EMBL:EAW87355.1}; Flags: Fragment;"]
[132321,"'C4orf33'",32,38,35,{"$nulls":5},"GO:0005515///protein binding",null,"IPR029674///UPF0462 protein C4orf33","[CD033_HUMAN|Reviewed]RecName: Full=UPF0462 protein C4orf33;+++[D6RD26_HUMAN|Unreviewed]SubName: Full=UPF0462 protein C4orf33 {ECO:0000313|Ensembl:ENSP00000427096}; Flags: Fragment;+++[D6RIS3_HUMAN|Unreviewed]SubName: Full=UPF0462 protein C4orf33 {ECO:0000313|Ensembl:ENSP00000427431}; Flags: Fragment;+++[D6RIT3_HUMAN|Unreviewed]SubName: Full=UPF0462 protein C4orf33 {ECO:0000313|Ensembl:ENSP00000427406};"]
[1329,"'COX5B'",1134,831,982.5,"04260///Cardiac muscle contraction+++00190///Oxidative phosphorylation+++05012///Parkinson's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05016///Huntington's disease+++01100///Metabolic pathways+++05010///Alzheimer's disease+++04714///Thermogenesis",null,"M00154///Cytochrome c oxidase",null,"GO:0005751///mitochondrial respiratory chain complex IV+++GO:0005740///mitochondrial envelope+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0004129///cytochrome-c oxidase activity+++GO:0046872///metal ion binding","GO:0007585///respiratory gaseous exchange+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0022900///electron transport chain+++GO:1902600///proton transmembrane transport+++GO:0042776///mitochondrial ATP synthesis coupled proton transport","IPR020893///Cytochrome c oxidase, subunit Vb, zinc binding site+++IPR036972///Cytochrome c oxidase, subunit Vb superfamily+++IPR002124///Cytochrome c oxidase, subunit Vb","[COX5B_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase subunit 5B, mitochondrial; AltName: Full=Cytochrome c oxidase polypeptide Vb; Flags: Precursor;+++[Q6FHJ9_HUMAN|Unreviewed]SubName: Full=COX5B protein {ECO:0000313|EMBL:CAG46553.1}; Flags: Fragment;+++[Q6FHM4_HUMAN|Unreviewed]SubName: Full=COX5B protein {ECO:0000313|EMBL:CAG46528.1};"]
[1337,"'COX6A1'",3914,2947,3430.5,"01100///Metabolic pathways+++05010///Alzheimer's disease+++04260///Cardiac muscle contraction+++04932///Non-alcoholic fatty liver disease (NAFLD)+++00190///Oxidative phosphorylation+++04714///Thermogenesis+++05016///Huntington's disease+++05012///Parkinson's disease","H00264///Charcot-Marie-Tooth disease (CMT)","M00154///Cytochrome c oxidase",null,"GO:0005751///mitochondrial respiratory chain complex IV+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0004129///cytochrome-c oxidase activity+++GO:0030234///enzyme regulator activity","GO:0050790///regulation of catalytic activity+++GO:0022900///electron transport chain+++GO:1902600///proton transmembrane transport+++GO:0009060///aerobic respiration+++GO:0006123///mitochondrial electron transport, cytochrome c to oxygen+++GO:0006091///generation of precursor metabolites and energy","IPR036418///Cytochrome c oxidase, subunit VIa superfamily+++IPR001349///Cytochrome c oxidase, subunit VIa+++IPR018507///Cytochrome c oxidase, subunit VIa, conserved site","[CX6A1_HUMAN|Reviewed]RecName: Full=Cytochrome c oxidase subunit 6A1, mitochondrial; AltName: Full=Cytochrome c oxidase polypeptide VIa-liver; AltName: Full=Cytochrome c oxidase subunit VIA-liver; Short=COX VIa-L; Flags: Precursor;+++[A0A024RBN6_HUMAN|Unreviewed]RecName: Full=Cytochrome c oxidase subunit 6A, mitochondrial {ECO:0000256|RuleBase:RU004397}; AltName: Full=Cytochrome c oxidase polypeptide VIa {ECO:0000256|RuleBase:RU004397};+++[H6SG15_HUMAN|Unreviewed]RecName: Full=Cytochrome c oxidase subunit 6A, mitochondrial {ECO:0000256|RuleBase:RU004397}; AltName: Full=Cytochrome c oxidase polypeptide VIa {ECO:0000256|RuleBase:RU004397};"]
[134353,"'LSM11'",54.05,108.24,81.145,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005654///nucleoplasm+++GO:0005697///telomerase holoenzyme complex+++GO:0005634///nucleus+++GO:0005683///U7 snRNP+++GO:0071204///histone pre-mRNA 3'end processing complex+++GO:0016604///nuclear body","GO:0005515///protein binding+++GO:0071209///U7 snRNA binding+++GO:0003723///RNA binding","GO:0006369///termination of RNA polymerase II transcription+++GO:0006397///mRNA processing+++GO:0008334///histone mRNA metabolic process+++GO:0006398///mRNA 3'-end processing by stem-loop binding and cleavage+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle","IPR034109///Sm-like protein Lsm11, middle domain+++IPR039267///U7 snRNA-associated Sm-like protein Lsm11+++IPR001163///LSM domain, eukaryotic/archaea-type+++IPR010920///LSM domain superfamily","[LSM11_HUMAN|Reviewed]RecName: Full=U7 snRNA-associated Sm-like protein LSm11;+++[L0R895_HUMAN|Unreviewed]SubName: Full=Alternative protein LSM11 {ECO:0000313|EMBL:CCO13766.1};"]
[134829,"'CLVS2'",1,2,1.5,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus+++GO:0030136///clathrin-coated vesicle+++GO:0031901///early endosome membrane+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0032588///trans-Golgi network membrane","GO:0080025///phosphatidylinositol-3,5-bisphosphate binding+++GO:0008289///lipid binding","GO:0007040///lysosome organization","IPR001251///CRAL-TRIO lipid binding domain+++IPR036273///CRAL/TRIO, N-terminal domain superfamily+++IPR028636///Clavesin-2+++IPR011074///CRAL/TRIO, N-terminal domain+++IPR036865///CRAL-TRIO lipid binding domain superfamily","[CLVS2_HUMAN|Reviewed]RecName: Full=Clavesin-2; AltName: Full=Retinaldehyde-binding protein 1-like 2; AltName: Full=clathrin vesicle-associated Sec14 protein 2 {ECO:0000303|PubMed:19651769};"]
[135398,"'C6orf141'",88,77,82.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated","IPR037739///Uncharacterized protein C6orf141","[CF141_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C6orf141;+++[A0A024RD72_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 141, isoform CRA_a {ECO:0000313|EMBL:EAX04336.1};+++[H0YDR2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C6orf141 {ECO:0000313|Ensembl:ENSP00000434131}; Flags: Fragment;"]
[136319,"'MTPN'",1016,1289.5,1152.75,{"$nulls":4},"GO:0030424///axon+++GO:0008290///F-actin capping protein complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm","GO:0043565///sequence-specific DNA binding","GO:0006417///regulation of translation+++GO:0006584///catecholamine metabolic process+++GO:0016202///regulation of striated muscle tissue development+++GO:0043403///skeletal muscle tissue regeneration+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0010557///positive regulation of macromolecule biosynthetic process+++GO:2000812///regulation of barbed-end actin filament capping+++GO:0030182///neuron differentiation+++GO:0051146///striated muscle cell differentiation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0030307///positive regulation of cell growth+++GO:0008361///regulation of cell size+++GO:0021707///cerebellar granule cell differentiation+++GO:0071260///cellular response to mechanical stimulus+++GO:0051247///positive regulation of protein metabolic process","IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR020683///Ankyrin repeat-containing domain","[MTPN_HUMAN|Reviewed]RecName: Full=Myotrophin; AltName: Full=Protein V-1;+++[C9JL85_HUMAN|Unreviewed]SubName: Full=Myotrophin {ECO:0000313|Ensembl:ENSP00000388321};+++[Q69YG1_HUMAN|Unreviewed]SubName: Full=Myotrophin {ECO:0000313|EMBL:EAL24056.1}; SubName: Full=Myotrophin, isoform CRA_a {ECO:0000313|EMBL:EAW83859.1}; SubName: Full=V-1 protein {ECO:0000313|EMBL:AAP97226.1}; SubName: Full=cDNA FLJ31663 fis, clone NT2RI2004504, highly similar to MYOTROPHIN {ECO:0000313|EMBL:BAG51651.1};"]
[137492,"'VPS37A'",522,536,529,"04144///Endocytosis","H00266///Hereditary spastic paraplegia (SPG)+++H01439///Williams-Beuren syndrome","M00409///ESCRT-I complex",null,"GO:0005634///nucleus+++GO:0010008///endosome membrane+++GO:0000813///ESCRT I complex+++GO:0005768///endosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0031902///late endosome membrane+++GO:0005813///centrosome+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding","GO:0019058///viral life cycle+++GO:0036258///multivesicular body assembly+++GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0039702///viral budding via host ESCRT complex+++GO:0016197///endosomal transport+++GO:0015031///protein transport+++GO:0032509///endosome transport via multivesicular body sorting pathway+++GO:0016236///macroautophagy","IPR037202///ESCRT assembly domain+++IPR037859///Vacuolar protein sorting-associated protein 37+++IPR009851///Modifier of rudimentary, Modr+++IPR029012///Helix hairpin bin domain superfamily+++IPR016135///Ubiquitin-conjugating enzyme/RWD-like","[VP37A_HUMAN|Reviewed]RecName: Full=Vacuolar protein sorting-associated protein 37A; Short=hVps37A; AltName: Full=ESCRT-I complex subunit VPS37A; AltName: Full=Hepatocellular carcinoma-related protein 1;+++[E5RG91_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 37A {ECO:0000313|Ensembl:ENSP00000428823};+++[E5RHB8_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 37A {ECO:0000313|Ensembl:ENSP00000430933};+++[E5RJ10_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 37A {ECO:0000313|Ensembl:ENSP00000429227};+++[E5RJX6_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 37A {ECO:0000313|Ensembl:ENSP00000430456}; Flags: Fragment;+++[H0YBN0_HUMAN|Unreviewed]SubName: Full=Vacuolar protein sorting-associated protein 37A {ECO:0000313|Ensembl:ENSP00000429858}; Flags: Fragment;"]
[1380,"'CR2'",0,2,1,"04640///Hematopoietic cell lineage+++04662///B cell receptor signaling pathway+++05169///Epstein-Barr virus infection+++04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0042803///protein homodimerization activity+++GO:0001848///complement binding+++GO:0003677///DNA binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0004875///complement receptor activity+++GO:0001618///virus receptor activity","GO:0046718///viral entry into host cell+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response+++GO:0030449///regulation of complement activation+++GO:0002430///complement receptor mediated signaling pathway+++GO:0030183///B cell differentiation+++GO:0016032///viral process+++GO:0006955///immune response+++GO:0042100///B cell proliferation+++GO:0002376///immune system process","IPR000436///Sushi/SCR/CCP domain+++IPR035976///Sushi/SCR/CCP superfamily","[CR2_HUMAN|Reviewed]RecName: Full=Complement receptor type 2; Short=Cr2; AltName: Full=Complement C3d receptor; AltName: Full=Epstein-Barr virus receptor; Short=EBV receptor; AltName: CD_antigen=CD21; Flags: Precursor;+++[A0A1W2PPV2_HUMAN|Unreviewed]SubName: Full=Complement receptor type 2 {ECO:0000313|Ensembl:ENSP00000491608};+++[Q08578_HUMAN|Unreviewed]SubName: Full=Complement receptor {ECO:0000313|EMBL:CAA48779.1}; Flags: Fragment;+++[Q5SR47_HUMAN|Unreviewed]SubName: Full=Complement receptor type 2 {ECO:0000313|Ensembl:ENSP00000356026};"]
[1386,"'ATF2'",372,430,401,"04668///TNF signaling pathway+++04911///Insulin secretion+++04624///Toll and Imd signaling pathway+++05169///Epstein-Barr virus infection+++04925///Aldosterone synthesis and secretion+++04013///MAPK signaling pathway - fly+++04211///Longevity regulating pathway+++04934///Cushing's syndrome+++04151///PI3K-Akt signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++05030///Cocaine addiction+++04010///MAPK signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action+++05161///Hepatitis B+++05034///Alcoholism+++04926///Relaxin signaling pathway+++05166///HTLV-I infection+++04728///Dopaminergic synapse+++04022///cGMP-PKG signaling pathway+++04714///Thermogenesis+++04922///Glucagon signaling pathway+++04915///Estrogen signaling pathway+++05031///Amphetamine addiction+++05163///Human cytomegalovirus infection+++05203///Viral carcinogenesis+++04927///Cortisol synthesis and secretion+++05164///Influenza A+++04918///Thyroid hormone synthesis",{"$nulls":3},"GO:0035861///site of double-strand break+++GO:0005741///mitochondrial outer membrane+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0003700///DNA-binding transcription factor activity+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0008140///cAMP response element binding protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0003682///chromatin binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003705///transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0035497///cAMP response element binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003713///transcription coactivator activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0004402///histone acetyltransferase activity","GO:0032197///transposition, RNA-mediated+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0110024///positive regulation of cardiac muscle myoblast proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006970///response to osmotic stress+++GO:1902110///positive regulation of mitochondrial membrane permeability involved in apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031573///intra-S DNA damage checkpoint+++GO:0010628///positive regulation of gene expression+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0009414///response to water deprivation+++GO:0032915///positive regulation of transforming growth factor beta2 production+++GO:0006310///DNA recombination+++GO:0060612///adipose tissue development+++GO:0016525///negative regulation of angiogenesis+++GO:0045444///fat cell differentiation+++GO:0097186///amelogenesis+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0003151///outflow tract morphogenesis","IPR029836///cAMP-dependent transcription factor ATF-2+++IPR016378///Transcription factor cyclic AMP-dependent, CRE-BP1-type+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR004827///Basic-leucine zipper domain","[ATF2_HUMAN|Reviewed]RecName: Full=Cyclic AMP-dependent transcription factor ATF-2; Short=cAMP-dependent transcription factor ATF-2; EC=2.3.1.48 {ECO:0000269|PubMed:10821277}; AltName: Full=Activating transcription factor 2; AltName: Full=Cyclic AMP-responsive element-binding protein 2; Short=CREB-2; Short=cAMP-responsive element-binding protein 2; AltName: Full=HB16; AltName: Full=Histone acetyltransferase ATF2; AltName: Full=cAMP response element-binding protein CRE-BP1;+++[A4D7V5_HUMAN|Unreviewed]SubName: Full=Activating transcription factor 2 splice variant ATF2-var12 {ECO:0000313|EMBL:AAY17214.1};"]
[1389,"'CREBL2'",456,433,444.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0050821///protein stabilization+++GO:0045600///positive regulation of fat cell differentiation+++GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0046326///positive regulation of glucose import+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0046889///positive regulation of lipid biosynthetic process+++GO:0007049///cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0006351///transcription, DNA-templated","IPR039250///cAMP-responsive element-binding protein-like 2+++IPR004827///Basic-leucine zipper domain","[CRBL2_HUMAN|Reviewed]RecName: Full=cAMP-responsive element-binding protein-like 2;+++[A0A024RAX5_HUMAN|Unreviewed]SubName: Full=cAMP responsive element binding protein-like 2, isoform CRA_a {ECO:0000313|EMBL:EAW96270.1}; Flags: Fragment;"]
[139735,"'ZFP92'",53,58,55.5,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily","[ZFP92_HUMAN|Reviewed]RecName: Full=Zinc finger protein 92 homolog; Short=Zfp-92;"]
[140465,"'MYL6B'",906,499,702.5,"04270///Vascular smooth muscle contraction+++04921///Oxytocin signaling pathway+++04530///Tight junction",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005859///muscle myosin complex+++GO:0016461///unconventional myosin complex+++GO:0016459///myosin complex","GO:0008307///structural constituent of muscle+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0003774///motor activity","GO:0030049///muscle filament sliding+++GO:0007519///skeletal muscle tissue development+++GO:0006936///muscle contraction","IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain","[MYL6B_HUMAN|Reviewed]RecName: Full=Myosin light chain 6B; AltName: Full=Myosin light chain 1 slow-twitch muscle A isoform; Short=MLC1sa; AltName: Full=Smooth muscle and nonmuscle myosin light chain alkali 6B;+++[A0A024RB31_HUMAN|Unreviewed]SubName: Full=Myosin, light polypeptide 6B, alkali, smooth muscle and non-muscle, isoform CRA_a {ECO:0000313|EMBL:EAW96896.1};+++[F8VSA2_HUMAN|Unreviewed]SubName: Full=Myosin light chain 6B {ECO:0000313|Ensembl:ENSP00000448198}; Flags: Fragment;+++[F8W1I5_HUMAN|Unreviewed]SubName: Full=Myosin light chain 6B {ECO:0000313|Ensembl:ENSP00000446965};"]
[140688,"'NOL4L'",719,945,832,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01481///Myelodysplastic syndrome (MDS)+++H02047///Bohring-Opitz syndrome",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000902///cell morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0032526///response to retinoic acid+++GO:0060430///lung saccule development+++GO:0003007///heart morphogenesis+++GO:0045599///negative regulation of fat cell differentiation+++GO:0048872///homeostasis of number of cells+++GO:0016579///protein deubiquitination+++GO:0035522///monoubiquitinated histone H2A deubiquitination+++GO:0048538///thymus development+++GO:0030097///hemopoiesis+++GO:0048539///bone marrow development+++GO:0035359///negative regulation of peroxisome proliferator activated receptor signaling pathway+++GO:0048386///positive regulation of retinoic acid receptor signaling pathway","IPR039788///Nucleolar protein 4 family+++IPR026746///Nucleolar protein 4-like","[NOL4L_HUMAN|Reviewed]RecName: Full=Nucleolar protein 4-like;+++[A0A087WTU5_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000478146};+++[A0A087X0N3_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000483523};+++[A0A1W2PQU1_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000492149};+++[H0Y778_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000410774}; Flags: Fragment;+++[Q5JYB6_HUMAN|Unreviewed]SubName: Full=Chromosome 20 open reading frame 112, isoform CRA_d {ECO:0000313|EMBL:EAW76370.1}; SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000317413};+++[Q5JYC0_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000364830};+++[Q5JYC2_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000364829}; Flags: Fragment;+++[Q5W149_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 4-like {ECO:0000313|Ensembl:ENSP00000201961}; Flags: Fragment;+++[Q6P0R2_HUMAN|Unreviewed]SubName: Full=LOC284804 protein {ECO:0000313|EMBL:AAH65483.1}; Flags: Fragment;"]
[140766,"'ADAMTS14'",268,335,301.5,{"$nulls":4},"GO:0005576///extracellular region","GO:0004222///metalloendopeptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity","GO:0030574///collagen catabolic process+++GO:0006508///proteolysis+++GO:0030199///collagen fibril organization","IPR024079///Metallopeptidase, catalytic domain superfamily+++IPR000884///Thrombospondin type-1 (TSP1) repeat+++IPR001590///Peptidase M12B, ADAM/reprolysin+++IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR013273///ADAMTS/ADAMTS-like+++IPR010909///PLAC+++IPR010294///ADAM-TS Spacer 1+++IPR002870///Peptidase M12B, propeptide+++IPR006586///ADAM, cysteine-rich","[ATS14_HUMAN|Reviewed]RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 14; Short=ADAM-TS 14; Short=ADAM-TS14; Short=ADAMTS-14; EC=3.4.24.-; Flags: Precursor;"]
[140890,"'SREK1'",647,597,622,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing","IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR033568///Splicing regulatory glutamine/lysine-rich protein 1+++IPR035979///RNA-binding domain superfamily+++IPR034192///SREK1, RNA recognition motif 2","[SREK1_HUMAN|Reviewed]RecName: Full=Splicing regulatory glutamine/lysine-rich protein 1; AltName: Full=Serine/arginine-rich-splicing regulatory protein 86; Short=SRrp86; AltName: Full=Splicing factor, arginine/serine-rich 12; AltName: Full=Splicing regulatory protein 508; Short=SRrp508;+++[A0A087WY03_HUMAN|Unreviewed]SubName: Full=Splicing regulatory glutamine/lysine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000481430};+++[E5RFV3_HUMAN|Unreviewed]SubName: Full=Splicing regulatory glutamine/lysine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000427935};+++[E5RJ76_HUMAN|Unreviewed]SubName: Full=Splicing regulatory glutamine/lysine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000428272}; Flags: Fragment;+++[E5RK30_HUMAN|Unreviewed]SubName: Full=Splicing regulatory glutamine/lysine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000428970};+++[H0YC47_HUMAN|Unreviewed]SubName: Full=Splicing regulatory glutamine/lysine-rich protein 1 {ECO:0000313|Ensembl:ENSP00000430894}; Flags: Fragment;"]
[142891,"'SAMD8'",279,311,295,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0030173///integral component of Golgi membrane+++GO:0005887///integral component of plasma membrane","GO:0033188///sphingomyelin synthase activity+++GO:0002950///ceramide phosphoethanolamine synthase activity+++GO:0003674///molecular_function+++GO:0047493///ceramide cholinephosphotransferase activity+++GO:0016740///transferase activity","GO:2000303///regulation of ceramide biosynthetic process+++GO:0006686///sphingomyelin biosynthetic process+++GO:0046513///ceramide biosynthetic process+++GO:0006665///sphingolipid metabolic process+++GO:1905373///ceramide phosphoethanolamine biosynthetic process+++GO:0030148///sphingolipid biosynthetic process+++GO:0006629///lipid metabolic process","IPR001660///Sterile alpha motif domain+++IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR025749///Sphingomyelin synthase-like domain","[SAMD8_HUMAN|Reviewed]RecName: Full=Sphingomyelin synthase-related protein 1; Short=SMSr; EC=2.7.8.-; AltName: Full=Ceramide phosphoethanolamine synthase; Short=CPE synthase; AltName: Full=Sterile alpha motif domain-containing protein 8; Short=SAM domain-containing protein 8;+++[A0A0A0MRR2_HUMAN|Unreviewed]SubName: Full=Sphingomyelin synthase-related protein 1 {ECO:0000313|Ensembl:ENSP00000361775};+++[Q5JSC9_HUMAN|Unreviewed]SubName: Full=Sphingomyelin synthase-related protein 1 {ECO:0000313|Ensembl:ENSP00000391799}; Flags: Fragment;+++[V9HVY4_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 177 {ECO:0000313|EMBL:ACF94485.1}; SubName: Full=Epididymis secretory sperm binding protein Li 181mP {ECO:0000313|EMBL:ACV87183.1}; SubName: Full=Sterile alpha motif domain containing 8, isoform CRA_c {ECO:0000313|EMBL:EAW54568.1};"]
[1434,"'CSE1L'",834,983,908.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005635///nuclear envelope+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0005049///nuclear export signal receptor activity+++GO:0008536///Ran GTPase binding+++GO:0008565///protein transporter activity+++GO:0005515///protein binding","GO:0015031///protein transport+++GO:0008283///cell proliferation+++GO:0006606///protein import into nucleus+++GO:0006611///protein export from nucleus+++GO:0006886///intracellular protein transport+++GO:0006915///apoptotic process","IPR001494///Importin-beta, N-terminal domain+++IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical+++IPR005043///Exportin-2, C-terminal+++IPR013713///Exportin-2, central domain","[XPO2_HUMAN|Reviewed]RecName: Full=Exportin-2; Short=Exp2; AltName: Full=Cellular apoptosis susceptibility protein {ECO:0000303|PubMed:7479798}; AltName: Full=Chromosome segregation 1-like protein; AltName: Full=Importin-alpha re-exporter;"]
[143888,"'KDELC2'",319.71,364.12,341.915,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component+++GO:0005788///endoplasmic reticulum lumen+++GO:0005783///endoplasmic reticulum","GO:0003674///molecular_function+++GO:0035252///UDP-xylosyltransferase activity+++GO:0035251///UDP-glucosyltransferase activity+++GO:0046527///glucosyltransferase activity","GO:0018242///protein O-linked glycosylation via serine+++GO:0008150///biological_process","IPR001298///Filamin/ABP280 repeat+++IPR006598///Lipopolysaccharide-modifying protein+++IPR013783///Immunoglobulin-like fold+++IPR014756///Immunoglobulin E-set+++IPR017868///Filamin/ABP280 repeat-like","[KDEL2_HUMAN|Reviewed]RecName: Full=KDEL motif-containing protein 2; Flags: Precursor;+++[A0A024R3C4_HUMAN|Unreviewed]SubName: Full=KDEL (Lys-Asp-Glu-Leu) containing 2, isoform CRA_a {ECO:0000313|EMBL:EAW67120.1};+++[H0YEM3_HUMAN|Unreviewed]SubName: Full=KDEL motif-containing protein 2 {ECO:0000313|Ensembl:ENSP00000436147}; Flags: Fragment;"]
[144348,"'ZNF664'",1604.56,2112.55,1858.555,{"$nulls":4},"GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0008150///biological_process+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN664_HUMAN|Reviewed]RecName: Full=Zinc finger protein 664; AltName: Full=Zinc finger protein 176 {ECO:0000312|HGNC:HGNC:25406}; AltName: Full=Zinc finger protein from organ of Corti;+++[A0A024RBR7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 664, isoform CRA_a {ECO:0000313|EMBL:EAW98446.1};+++[A0A024RBR8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 664, isoform CRA_b {ECO:0000313|EMBL:EAW98443.1};+++[Q0P6D9_HUMAN|Unreviewed]SubName: Full=ZNF664 protein {ECO:0000313|EMBL:AAH17960.1};"]
[144717,"'PHETA1'",392,361,376.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0030136///clathrin-coated vesicle+++GO:0055037///recycling endosome+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0007032///endosome organization+++GO:0001881///receptor recycling+++GO:0042147///retrograde transport, endosome to Golgi","IPR011993///PH-like domain superfamily+++IPR001849///Pleckstrin homology domain","[SESQ1_HUMAN|Reviewed]RecName: Full=Sesquipedalian-1 {ECO:0000305|PubMed:20133602}; Short=Ses1; AltName: Full=27 kDa inositol polyphosphate phosphatase-interacting protein A; Short=IPIP27A; AltName: Full=PH domain-containing endocytic trafficking adaptor 1 {ECO:0000305};+++[F8VZK7_HUMAN|Unreviewed]SubName: Full=Sesquipedalian-1 {ECO:0000313|Ensembl:ENSP00000447349}; Flags: Fragment;+++[F8W0V2_HUMAN|Unreviewed]SubName: Full=Sesquipedalian-1 {ECO:0000313|Ensembl:ENSP00000447539}; Flags: Fragment;+++[G3V0F1_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 109, member A, isoform CRA_d {ECO:0000313|EMBL:EAW97953.1};"]
[145482,"'PTGR2'",66,83,74.5,{"$nulls":4},"GO:0005737///cytoplasm","GO:0016491///oxidoreductase activity+++GO:0047522///15-oxoprostaglandin 13-oxidase activity+++GO:0008270///zinc ion binding+++GO:0036132///13-prostaglandin reductase activity","GO:0055114///oxidation-reduction process+++GO:0006693///prostaglandin metabolic process","IPR037399///Prostaglandin reductase 2+++IPR013149///Alcohol dehydrogenase, C-terminal+++IPR036291///NAD(P)-binding domain superfamily+++IPR011032///GroES-like superfamily","[PTGR2_HUMAN|Reviewed]RecName: Full=Prostaglandin reductase 2; Short=PRG-2; EC=1.3.1.48; AltName: Full=15-oxoprostaglandin 13-reductase; AltName: Full=Zinc-binding alcohol dehydrogenase domain-containing protein 1;+++[G3V2R9_HUMAN|Unreviewed]SubName: Full=Prostaglandin reductase 2 {ECO:0000313|Ensembl:ENSP00000450824};+++[V9HW32_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 298 {ECO:0000313|EMBL:ACI46026.1}; SubName: Full=Zinc binding alcohol dehydrogenase, domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW81135.1};"]
[145864,"'HAPLN3'",488,529,508.5,null,"H00448///Familial osteochondritis dissecans+++H00765///Spondyloepiphyseal dysplasia, Kimberley type",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix","GO:0005540///hyaluronic acid binding","GO:0007417///central nervous system development+++GO:0007155///cell adhesion","IPR016186///C-type lectin-like/link domain superfamily+++IPR003599///Immunoglobulin subtype+++IPR007110///Immunoglobulin-like domain+++IPR013106///Immunoglobulin V-set domain+++IPR016187///C-type lectin fold+++IPR036179///Immunoglobulin-like domain superfamily+++IPR000538///Link domain+++IPR013783///Immunoglobulin-like fold","[HPLN3_HUMAN|Reviewed]RecName: Full=Hyaluronan and proteoglycan link protein 3; Flags: Precursor;+++[A0A024RC58_HUMAN|Unreviewed]SubName: Full=Hyaluronan and proteoglycan link protein 3, isoform CRA_a {ECO:0000313|EMBL:EAX02024.1};+++[A8K7T8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77776, highly similar to Homo sapiens hyaluronan and proteoglycan link protein 3 (HAPLN3), mRNA {ECO:0000313|EMBL:BAF84792.1};+++[H3BRY4_HUMAN|Unreviewed]SubName: Full=Hyaluronan and proteoglycan link protein 3, isoform CRA_b {ECO:0000313|EMBL:EAX02023.1};+++[H3BT26_HUMAN|Unreviewed]SubName: Full=Hyaluronan and proteoglycan link protein 3 {ECO:0000313|Ensembl:ENSP00000456985}; Flags: Fragment;+++[H3BTH8_HUMAN|Unreviewed]SubName: Full=Hyaluronan and proteoglycan link protein 3 {ECO:0000313|Ensembl:ENSP00000457180};"]
[146227,"'BEAN1'",58,84,71,null,"H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR039352///Protein BEAN1","[BEAN1_HUMAN|Reviewed]RecName: Full=Protein BEAN1; AltName: Full=Brain-expressed protein associating with Nedd4 homolog; Short=BEAN;+++[A0A087WTF9_HUMAN|Unreviewed]SubName: Full=Protein BEAN1 {ECO:0000313|Ensembl:ENSP00000477843};+++[H3BRW1_HUMAN|Unreviewed]SubName: Full=Protein BEAN1 {ECO:0000313|Ensembl:ENSP00000456430};+++[J3KRN6_HUMAN|Unreviewed]SubName: Full=Protein BEAN1 {ECO:0000313|Ensembl:ENSP00000462088}; Flags: Fragment;"]
[146547,"'PRSS36'",33,14,23.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis","IPR001314///Peptidase S1A, chymotrypsin family+++IPR017326///Peptidase S1A, polyserase-2+++IPR018114///Serine proteases, trypsin family, histidine active site+++IPR033116///Serine proteases, trypsin family, serine active site+++IPR001254///Serine proteases, trypsin domain+++IPR009003///Peptidase S1, PA clan","[POLS2_HUMAN|Reviewed]RecName: Full=Polyserase-2; EC=3.4.21.-; AltName: Full=Polyserine protease 2; AltName: Full=Serine protease 36; Flags: Precursor;+++[B4DNP1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55455, highly similar to Polyserase-2 {ECO:0000313|EMBL:BAG60303.1};+++[I3L3A6_HUMAN|Unreviewed]SubName: Full=Polyserase-2 {ECO:0000313|Ensembl:ENSP00000460298}; Flags: Fragment;"]
[146862,"'UNC45B'",1,2,1.5,null,"H01202///Cataract",null,null,"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0051879///Hsp90 protein binding","GO:0007517///muscle organ development+++GO:0030154///cell differentiation+++GO:0061077///chaperone-mediated protein folding+++GO:0002088///lens development in camera-type eye+++GO:0007275///multicellular organism development","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR000225///Armadillo+++IPR024660///UNC-45/Cro1/She4, central domain+++IPR016024///Armadillo-type fold+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR011989///Armadillo-like helical+++IPR019734///Tetratricopeptide repeat","[UN45B_HUMAN|Reviewed]RecName: Full=Protein unc-45 homolog B; Short=Unc-45B; AltName: Full=SMUNC45;+++[A0A1B1PFW5_HUMAN|Unreviewed]SubName: Full=Unc-45 myosin chaperone B {ECO:0000313|EMBL:ANT47186.1}; Flags: Fragment;+++[H0UID2_HUMAN|Unreviewed]SubName: Full=Unc-45 homolog B (C. elegans), isoform CRA_b {ECO:0000313|EMBL:EAW80164.1};"]
[146894,"'CD300LG'",0,1.1,0.55,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016324///apical plasma membrane+++GO:0032585///multivesicular body membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005768///endosome+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0002376///immune system process+++GO:0050776///regulation of immune response","IPR007110///Immunoglobulin-like domain+++IPR013106///Immunoglobulin V-set domain+++IPR013783///Immunoglobulin-like fold+++IPR003599///Immunoglobulin subtype+++IPR036179///Immunoglobulin-like domain superfamily","[CLM9_HUMAN|Reviewed]RecName: Full=CMRF35-like molecule 9; Short=CLM-9; AltName: Full=CD300 antigen-like family member G; AltName: Full=Triggering receptor expressed on myeloid cells 4; Short=TREM-4; AltName: CD_antigen=CD300g; Flags: Precursor;+++[K7EL06_HUMAN|Unreviewed]SubName: Full=CMRF35-like molecule 9 {ECO:0000313|Ensembl:ENSP00000465863};"]
[147179,"'WIPF2'",1176.01,1499,1337.505,"04144///Endocytosis","H01523///Wiskott-Aldrich syndrome",null,null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005884///actin filament+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0030479///actin cortical patch","GO:0005515///protein binding+++GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0000147///actin cortical patch assembly+++GO:0051127///positive regulation of actin nucleation+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0030048///actin filament-based movement+++GO:0006897///endocytosis+++GO:0051666///actin cortical patch localization","IPR003124///WH2 domain+++IPR028294///WAS/WASL-interacting protein family member 2","[WIPF2_HUMAN|Reviewed]RecName: Full=WAS/WASL-interacting protein family member 2; AltName: Full=WASP-interacting protein-related protein; AltName: Full=WIP- and CR16-homologous protein; AltName: Full=WIP-related protein;+++[A0A024R1X2_HUMAN|Unreviewed]SubName: Full=WIRE protein, isoform CRA_a {ECO:0000313|EMBL:EAW60649.1};+++[A8MWR2_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000377663}; SubName: Full=cDNA FLJ30495 fis, clone BRAWH2000323, moderately similar to WIP-related protein {ECO:0000313|EMBL:BAG51456.1};+++[J3KSA3_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000462386}; Flags: Fragment;+++[J3QKM5_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000463149}; Flags: Fragment;+++[J3QQS0_HUMAN|Unreviewed]SubName: Full=WAS/WASL-interacting protein family member 2 {ECO:0000313|Ensembl:ENSP00000463869};"]
[147670,"'SMIM17'",1,3.77,2.385,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane",{"$nulls":3},"[SIM17_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 17;+++[M0R1N7_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 17 {ECO:0000313|Ensembl:ENSP00000472019};"]
[147807,"'ZNF524'",194,166,180,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN524_HUMAN|Reviewed]RecName: Full=Zinc finger protein 524;+++[K7EP10_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 524 {ECO:0000313|Ensembl:ENSP00000467175}; Flags: Fragment;"]
[147991,"'DPY19L3'",135,171,153,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005637///nuclear inner membrane","GO:0000030///mannosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0018406///protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan","IPR030039///Probable C-mannosyltransferase DPY19L3+++IPR018732///Dpy-19/Dpy-19-like","[D19L3_HUMAN|Reviewed]RecName: Full=Probable C-mannosyltransferase DPY19L3; EC=2.4.1.-; AltName: Full=Dpy-19-like protein 3; AltName: Full=Protein dpy-19 homolog 3;+++[K7ELB5_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L3 {ECO:0000313|Ensembl:ENSP00000465997}; Flags: Fragment;+++[K7ELG1_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L3 {ECO:0000313|Ensembl:ENSP00000466062}; Flags: Fragment;+++[K7ELH8_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L3 {ECO:0000313|Ensembl:ENSP00000466086};+++[Q8N6Q4_HUMAN|Unreviewed]SubName: Full=Dpy-19-like 3 (C. elegans) {ECO:0000313|EMBL:AAH29162.1}; SubName: Full=Probable C-mannosyltransferase DPY19L3 {ECO:0000313|Ensembl:ENSP00000465995};+++[S4R3D3_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L3 {ECO:0000313|Ensembl:ENSP00000474174}; Flags: Fragment;"]
[148254,"'ZNF555'",53,58.1,55.55,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type","[ZN555_HUMAN|Reviewed]RecName: Full=Zinc finger protein 555;+++[K7ENK0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 555 {ECO:0000313|Ensembl:ENSP00000466982}; Flags: Fragment;"]
[148741,"'ANKRD35'",2,1,1.5,{"$nulls":7},"IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR020683///Ankyrin repeat-containing domain","[ANR35_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 35;+++[B4DFX6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58791, highly similar to Ankyrin repeat domain-containing protein 35 {ECO:0000313|EMBL:BAG57587.1};+++[F6XZD3_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 35 {ECO:0000313|Ensembl:ENSP00000442671};"]
[149281,"'METTL11B'",1,0,0.5,{"$nulls":4},"GO:0005634///nucleus","GO:0071885///N-terminal protein N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0008168///methyltransferase activity","GO:0006480///N-terminal protein amino acid methylation+++GO:0032259///methylation","IPR008576///Alpha-N-methyltransferase NTM1+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[NTM1B_HUMAN|Reviewed]RecName: Full=Alpha N-terminal protein methyltransferase 1B; EC=2.1.1.299; AltName: Full=Methyltransferase-like protein 11B; AltName: Full=X-Pro-Lys N-terminal protein methyltransferase 1B; Short=NTM1B;"]
[149708,"'WFDC5'",4,0,2,{"$nulls":4},"GO:0005576///extracellular region","GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0030414///peptidase inhibitor activity","GO:0010466///negative regulation of peptidase activity+++GO:0010951///negative regulation of endopeptidase activity","IPR036645///Elafin-like superfamily+++IPR008197///WAP-type 'four-disulfide core' domain+++IPR029714///WAP four-disulfide core domain protein 5","[WFDC5_HUMAN|Reviewed]RecName: Full=WAP four-disulfide core domain protein 5; AltName: Full=Putative protease inhibitor WAP1; AltName: Full=p53-responsive gene 5 protein; Flags: Precursor;"]
[150209,"'AIFM3'",4,3,3.5,{"$nulls":4},"GO:0005743///mitochondrial inner membrane+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum","GO:0046872///metal ion binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0051536///iron-sulfur cluster binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0006915///apoptotic process+++GO:0097194///execution phase of apoptosis","IPR023753///FAD/NAD(P)-binding domain+++IPR036922///Rieske [2Fe-2S] iron-sulphur domain superfamily+++IPR028202///Reductase, C-terminal+++IPR016156///FAD/NAD-linked reductase, dimerisation domain superfamily+++IPR036188///FAD/NAD(P)-binding domain superfamily+++IPR017941///Rieske [2Fe-2S] iron-sulphur domain+++IPR000103///Pyridine nucleotide-disulphide oxidoreductase, class-II","[AIFM3_HUMAN|Reviewed]RecName: Full=Apoptosis-inducing factor 3; EC=1.-.-.-; AltName: Full=Apoptosis-inducing factor-like protein;+++[B7Z376_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53334, highly similar to Homo sapiens apoptosis-inducing factor like (AIFL), transcript variant 2, mRNA {ECO:0000313|EMBL:BAH12112.1};+++[C9JPU8_HUMAN|Unreviewed]SubName: Full=Apoptosis-inducing factor 3 {ECO:0000313|Ensembl:ENSP00000402067}; Flags: Fragment;+++[C9K029_HUMAN|Unreviewed]SubName: Full=Apoptosis-inducing factor 3 {ECO:0000313|Ensembl:ENSP00000399657}; Flags: Fragment;+++[F8WC30_HUMAN|Unreviewed]SubName: Full=Apoptosis-inducing factor 3 {ECO:0000313|Ensembl:ENSP00000406989};+++[F8WFB6_HUMAN|Unreviewed]SubName: Full=Apoptosis-inducing factor 3 {ECO:0000313|Ensembl:ENSP00000412973};"]
[150590,"'C2orf15'",7,7,7,"01100///Metabolic pathways+++00785///Lipoic acid metabolism",null,null,"R07771///Lipoyl-AMP + Apoprotein <=> Protein N6-(lipoyl)lysine + AMP","GO:0031965///nuclear membrane+++GO:0043005///neuron projection+++GO:0031514///motile cilium+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm","GO:0003723///RNA binding","GO:0030031///cell projection assembly+++GO:0007283///spermatogenesis+++GO:0034641///cellular nitrogen compound metabolic process+++GO:0006629///lipid metabolic process+++GO:0009249///protein lipoylation+++GO:0006464///cellular protein modification process","IPR004143///Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain+++IPR033323///Testis-specific gene 10 protein+++IPR004562///Lipoyltransferase/lipoate-protein ligase","[CB015_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C2orf15;+++[B2RAC6_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94831 {ECO:0000313|EMBL:BAG36823.1};"]
[151011,"'SEPT10'",404,434,419,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005940///septin ring+++GO:0032160///septin filament array+++GO:0031105///septin complex+++GO:0005737///cytoplasm","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity","GO:0007049///cell cycle+++GO:0060271///cilium assembly+++GO:0000281///mitotic cytokinesis+++GO:0000921///septin ring assembly+++GO:0051301///cell division","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR030379///Septin-type guanine nucleotide-binding (G) domain+++IPR016491///Septin","[SEP10_HUMAN|Reviewed]RecName: Full=Septin-10;+++[B5ME97_HUMAN|Unreviewed]SubName: Full=Septin 10, isoform CRA_c {ECO:0000313|EMBL:EAW53860.1}; SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000349116};+++[B7Z277_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59501, highly similar to Septin-10 {ECO:0000313|EMBL:BAH11763.1};+++[B7Z371_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55844, highly similar to Septin-10 {ECO:0000313|EMBL:BAH12107.1};+++[C9JEQ7_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000416597}; Flags: Fragment;+++[C9JEW2_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000396051}; Flags: Fragment;+++[C9JNR7_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000408392}; Flags: Fragment;+++[E7EW69_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000396728};+++[E7EX04_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000407790};+++[F5GYV2_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000441218}; Flags: Fragment;+++[F5H1F2_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000445707}; Flags: Fragment;+++[F5H1W3_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000446331};+++[F8WC85_HUMAN|Unreviewed]SubName: Full=Septin-10 {ECO:0000313|Ensembl:ENSP00000399270};+++[Q59H84_HUMAN|Unreviewed]SubName: Full=Septin 10 isoform 2 variant {ECO:0000313|EMBL:BAD92112.1}; Flags: Fragment;+++[Q9H9P7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12620 fis, clone NT2RM4001714, moderately similar to SEPTIN 2 HOMOLOG {ECO:0000313|EMBL:BAB14176.1};"]
[151295,"'SLC23A3'",20,11,15.5,"03450///Non-homologous end-joining","H00924///Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport","IPR029957///Solute carrier family 23 member 3+++IPR006043///Xanthine/uracil/vitamin C permease","[S23A3_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 3; AltName: Full=HPC E2-binding protein 3; AltName: Full=Na(+)/L-ascorbic acid transporter 3; AltName: Full=Sodium-dependent vitamin C transporter 3;+++[A0A0A0MSG3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 3 {ECO:0000313|Ensembl:ENSP00000386989}; Flags: Fragment;+++[B7Z508_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60757, moderately similar to Mus musculus solute carrier family 23 (nucleobase transporters), member 3, mRNA {ECO:0000313|EMBL:BAH12744.1};+++[C9JQ03_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 3 {ECO:0000313|Ensembl:ENSP00000388907}; Flags: Fragment;+++[H7C2A2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 member 3 {ECO:0000313|Ensembl:ENSP00000404697}; Flags: Fragment;+++[Q2PYN5_HUMAN|Unreviewed]SubName: Full=E2-binding protein 3 {ECO:0000313|EMBL:ABC17636.1};"]
[151651,"'EFHB'",5,12,8.5,"05146///Amoebiasis+++04962///Vasopressin-regulated water reabsorption+++04014///Ras signaling pathway+++04145///Phagosome+++05152///Tuberculosis+++04144///Endocytosis+++05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0005829///cytosol+++GO:0005768///endosome+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0031901///early endosome membrane+++GO:0005769///early endosome+++GO:0010008///endosome membrane+++GO:0070062///extracellular exosome+++GO:0008021///synaptic vesicle+++GO:0036477///somatodendritic compartment+++GO:0005886///plasma membrane+++GO:0045121///membrane raft+++GO:0043679///axon terminus+++GO:0030424///axon+++GO:0030665///clathrin-coated vesicle membrane+++GO:0043025///neuronal cell body+++GO:0043195///terminal bouton+++GO:0015629///actin cytoskeleton+++GO:0098559///cytoplasmic side of early endosome membrane+++GO:0030139///endocytic vesicle+++GO:0042470///melanosome+++GO:0030425///dendrite+++GO:0030670///phagocytic vesicle membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0006909///phagocytosis+++GO:0045921///positive regulation of exocytosis+++GO:2000286///receptor internalization involved in canonical Wnt signaling pathway+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0030100///regulation of endocytosis+++GO:0045056///transcytosis+++GO:0036465///synaptic vesicle recycling+++GO:0061024///membrane organization+++GO:0039694///viral RNA genome replication+++GO:0051036///regulation of endosome size+++GO:0007596///blood coagulation+++GO:0045022///early endosome to late endosome transport+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0015031///protein transport+++GO:2000785///regulation of autophagosome assembly+++GO:0043687///post-translational protein modification+++GO:0006897///endocytosis+++GO:0051489///regulation of filopodium assembly","IPR002048///EF-hand domain+++IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair","[EFHB_HUMAN|Reviewed]RecName: Full=EF-hand domain-containing family member B;+++[H7C0U4_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing family member B {ECO:0000313|Ensembl:ENSP00000396778}; Flags: Fragment;+++[H9KV82_HUMAN|Unreviewed]SubName: Full=EF-hand domain-containing family member B {ECO:0000313|Ensembl:ENSP00000373908};"]
[152078,"'PQLC2L'",20,18,19,{"$nulls":4},"GO:0016021///integral component of membrane",{"$nulls":3},"[CC055_HUMAN|Reviewed]RecName: Full=Putative uncharacterized protein PQLC2L {ECO:0000305}; AltName: Full=PQ-loop repeat-containing protein 2-like {ECO:0000312|HGNC:HGNC:25146};+++[C9J2K9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PQLC2L {ECO:0000313|Ensembl:ENSP00000417372};+++[C9JRW5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PQLC2L {ECO:0000313|Ensembl:ENSP00000420049};"]
[1525,"'CXADR'",509.34,813.15,661.245,"05416///Viral myocarditis",{"$nulls":3},"GO:0030175///filopodium+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0030426///growth cone+++GO:0030054///cell junction+++GO:0005923///bicellular tight junction+++GO:0005913///cell-cell adherens junction+++GO:0044297///cell body+++GO:0005912///adherens junction+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction+++GO:0016021///integral component of membrane+++GO:0031594///neuromuscular junction+++GO:0005887///integral component of plasma membrane+++GO:0043005///neuron projection+++GO:0045121///membrane raft+++GO:0016327///apicolateral plasma membrane+++GO:0005654///nucleoplasm+++GO:0005576///extracellular region+++GO:0001669///acrosomal vesicle+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc","GO:0001618///virus receptor activity+++GO:0005102///signaling receptor binding+++GO:0050839///cell adhesion molecule binding+++GO:0005178///integrin binding+++GO:0086082///cell adhesive protein binding involved in AV node cell-bundle of His cell communication+++GO:0005515///protein binding+++GO:0030165///PDZ domain binding+++GO:0071253///connexin binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding","GO:0031532///actin cytoskeleton reorganization+++GO:0007005///mitochondrion organization+++GO:0046718///viral entry into host cell+++GO:0016032///viral process+++GO:0051607///defense response to virus+++GO:0034109///homotypic cell-cell adhesion+++GO:0086067///AV node cell to bundle of His cell communication+++GO:0086072///AV node cell-bundle of His cell adhesion involved in cell communication+++GO:0046629///gamma-delta T cell activation+++GO:0070633///transepithelial transport+++GO:0010669///epithelial structure maintenance+++GO:0098609///cell-cell adhesion+++GO:0098904///regulation of AV node cell action potential+++GO:0050900///leukocyte migration+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0008354///germ cell migration+++GO:0045216///cell-cell junction organization+++GO:0030593///neutrophil chemotaxis+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007507///heart development+++GO:0007155///cell adhesion+++GO:0048739///cardiac muscle fiber development+++GO:0050776///regulation of immune response","IPR007110///Immunoglobulin-like domain+++IPR003598///Immunoglobulin subtype 2+++IPR013106///Immunoglobulin V-set domain+++IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013151///Immunoglobulin+++IPR003599///Immunoglobulin subtype","[CXAR_HUMAN|Reviewed]RecName: Full=Coxsackievirus and adenovirus receptor; Short=CAR; Short=hCAR; AltName: Full=CVB3-binding protein; AltName: Full=Coxsackievirus B-adenovirus receptor; AltName: Full=HCVADR; Flags: Precursor;"]
[152926,"'PPM1K'",157.62,149.01,153.315,null,"H00172///Maple syrup urine disease (MSUD)",null,null,"GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0046872///metal ion binding+++GO:0043169///cation binding+++GO:0016787///hydrolase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0003824///catalytic activity+++GO:0005515///protein binding","GO:0009083///branched-chain amino acid catabolic process+++GO:0006470///protein dephosphorylation","IPR036457///PPM-type phosphatase domain superfamily+++IPR001932///PPM-type phosphatase domain+++IPR000222///PPM-type phosphatase, divalent cation binding+++IPR015655///Protein phosphatase 2C family","[PPM1K_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1K, mitochondrial; EC=3.1.3.16; AltName: Full=PP2C domain-containing protein phosphatase 1K; AltName: Full=PP2C-like mitochondrial protein; AltName: Full=PP2C-type mitochondrial phosphoprotein phosphatase; Short=PTMP; AltName: Full=Protein phosphatase 2C isoform kappa; Short=PP2C-kappa; Flags: Precursor;+++[A0A0A0MQZ4_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1K, mitochondrial {ECO:0000313|Ensembl:ENSP00000295908};+++[V9GY69_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1K, mitochondrial {ECO:0000313|Ensembl:ENSP00000476452};+++[V9GYI6_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1K, mitochondrial {ECO:0000313|Ensembl:ENSP00000476789}; Flags: Fragment;+++[V9GYS8_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1K, mitochondrial {ECO:0000313|Ensembl:ENSP00000477051}; Flags: Fragment;+++[V9GYZ5_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 1K (PP2C domain containing), isoform CRA_b {ECO:0000313|EMBL:EAX06015.1}; SubName: Full=Protein phosphatase 1K, mitochondrial {ECO:0000313|Ensembl:ENSP00000477241};"]
[1535,"'CYBA'",3669.02,2708,3188.51,"04380///Osteoclast differentiation+++04621///NOD-like receptor signaling pathway+++04145///Phagosome+++05418///Fluid shear stress and atherosclerosis+++05140///Leishmaniasis+++04670///Leukocyte transendothelial migration","H00098///Chronic granulomatous disease+++H01167///Gluconobacter infection",null,null,"GO:0005794///Golgi apparatus+++GO:0030670///phagocytic vesicle membrane+++GO:0016021///integral component of membrane+++GO:0001725///stress fiber+++GO:0043025///neuronal cell body+++GO:0005768///endosome+++GO:0030141///secretory granule+++GO:0005789///endoplasmic reticulum membrane+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0005634///nucleus+++GO:0016324///apical plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0043020///NADPH oxidase complex+++GO:0005886///plasma membrane+++GO:0070821///tertiary granule membrane+++GO:0030425///dendrite+++GO:0035579///specific granule membrane","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0046982///protein heterodimerization activity+++GO:0017124///SH3 domain binding+++GO:0009055///electron transfer activity+++GO:0020037///heme binding+++GO:0016491///oxidoreductase activity","GO:0022900///electron transport chain+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0045087///innate immune response+++GO:0032930///positive regulation of superoxide anion generation+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:0017004///cytochrome complex assembly+++GO:0006954///inflammatory response+++GO:0071480///cellular response to gamma radiation+++GO:0070257///positive regulation of mucus secretion+++GO:0014895///smooth muscle hypertrophy+++GO:0001666///response to hypoxia+++GO:0031667///response to nutrient levels+++GO:0071230///cellular response to amino acid stimulus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0045730///respiratory burst+++GO:1900426///positive regulation of defense response to bacterium+++GO:0071407///cellular response to organic cyclic compound+++GO:0070555///response to interleukin-1+++GO:0055114///oxidation-reduction process+++GO:0042554///superoxide anion generation+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0006801///superoxide metabolic process+++GO:0042493///response to drug+++GO:0071310///cellular response to organic substance+++GO:0014823///response to activity+++GO:1904845///cellular response to L-glutamine+++GO:0043312///neutrophil degranulation+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:1904385///cellular response to angiotensin+++GO:1904044///response to aldosterone+++GO:0030307///positive regulation of cell growth+++GO:0072593///reactive oxygen species metabolic process+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0034599///cellular response to oxidative stress+++GO:0050665///hydrogen peroxide biosynthetic process+++GO:0071333///cellular response to glucose stimulus+++GO:0003106///negative regulation of glomerular filtration by angiotensin+++GO:0051279///regulation of release of sequestered calcium ion into cytosol+++GO:0032755///positive regulation of interleukin-6 production+++GO:0071260///cellular response to mechanical stimulus+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0050766///positive regulation of phagocytosis+++GO:0045777///positive regulation of blood pressure","IPR007732///Cytochrome b558 alpha-subunit","[CY24A_HUMAN|Reviewed]RecName: Full=Cytochrome b-245 light chain; AltName: Full=Cytochrome b(558) alpha chain; AltName: Full=Cytochrome b558 subunit alpha; AltName: Full=Neutrophil cytochrome b 22 kDa polypeptide; AltName: Full=Superoxide-generating NADPH oxidase light chain subunit; AltName: Full=p22 phagocyte B-cytochrome; AltName: Full=p22-phox; Short=p22phox;+++[B4DT46_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57889, highly similar to Cytochrome b-245 light chain {ECO:0000313|EMBL:BAG61858.1};+++[H3BNP7_HUMAN|Unreviewed]SubName: Full=Cytochrome b-245 light chain {ECO:0000313|Ensembl:ENSP00000454951};+++[H3BPX1_HUMAN|Unreviewed]SubName: Full=Cytochrome b-245 light chain {ECO:0000313|Ensembl:ENSP00000455506}; Flags: Fragment;+++[H3BPZ7_HUMAN|Unreviewed]SubName: Full=Cytochrome b-245 light chain {ECO:0000313|Ensembl:ENSP00000455537}; Flags: Fragment;+++[H3BR52_HUMAN|Unreviewed]SubName: Full=Cytochrome b-245 light chain {ECO:0000313|Ensembl:ENSP00000456079};+++[H3BT77_HUMAN|Unreviewed]SubName: Full=Cytochrome b-245 light chain {ECO:0000313|Ensembl:ENSP00000457060}; Flags: Fragment;+++[Q86SL0_HUMAN|Unreviewed]SubName: Full=Flavocytochrome b-558 alpha polypeptide {ECO:0000313|EMBL:AAM96953.1}; Flags: Fragment;"]
[154,"'ADRB2'",47,24,35.5,"04924///Renin secretion+++04024///cAMP signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04970///Salivary secretion+++04923///Regulation of lipolysis in adipocytes+++04020///Calcium signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04022///cGMP-PKG signaling pathway","H00079///Asthma+++H02106///Genetic obesity",null,null,"GO:0005634///nucleus+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0010008///endosome membrane+++GO:0005887///integral component of plasma membrane+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005769///early endosome+++GO:0016324///apical plasma membrane","GO:0005515///protein binding+++GO:0051379///epinephrine binding+++GO:0044877///protein-containing complex binding+++GO:0019899///enzyme binding+++GO:0004930///G protein-coupled receptor activity+++GO:0015459///potassium channel regulator activity+++GO:0051380///norepinephrine binding+++GO:0004935///adrenergic receptor activity+++GO:0042803///protein homodimerization activity+++GO:0008179///adenylate cyclase binding+++GO:0004941///beta2-adrenergic receptor activity+++GO:0001540///amyloid-beta binding","GO:0010739///positive regulation of protein kinase A signaling+++GO:2000481///positive regulation of cAMP-dependent protein kinase activity+++GO:0008333///endosome to lysosome transport+++GO:0031649///heat generation+++GO:0030501///positive regulation of bone mineralization+++GO:1904504///positive regulation of lipophagy+++GO:1990911///response to psychosocial stress+++GO:0007171///activation of transmembrane receptor protein tyrosine kinase activity+++GO:0009409///response to cold+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0031398///positive regulation of protein ubiquitination+++GO:1904646///cellular response to amyloid-beta+++GO:0002025///norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure+++GO:0040015///negative regulation of multicellular organism growth+++GO:0006898///receptor-mediated endocytosis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0061885///positive regulation of mini excitatory postsynaptic potential+++GO:0007165///signal transduction+++GO:0045453///bone resorption+++GO:0002028///regulation of sodium ion transport+++GO:0007190///activation of adenylate cyclase activity+++GO:0002024///diet induced thermogenesis+++GO:0050873///brown fat cell differentiation+++GO:0061024///membrane organization+++GO:0045986///negative regulation of smooth muscle contraction+++GO:0043410///positive regulation of MAPK cascade+++GO:0007166///cell surface receptor signaling pathway+++GO:0071880///adenylate cyclase-activating adrenergic receptor signaling pathway+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0002032///desensitization of G protein-coupled receptor signaling pathway by arrestin+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006940///regulation of smooth muscle contraction+++GO:0097746///regulation of blood vessel diameter+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:1901098///positive regulation of autophagosome maturation+++GO:0071875///adrenergic receptor signaling pathway+++GO:2000969///positive regulation of AMPA receptor activity+++GO:0001993///regulation of systemic arterial blood pressure by norepinephrine-epinephrine+++GO:0016579///protein deubiquitination","IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR000332///Beta 2 adrenoceptor+++IPR002233///Adrenoceptor family+++IPR017452///GPCR, rhodopsin-like, 7TM","[ADRB2_HUMAN|Reviewed]RecName: Full=Beta-2 adrenergic receptor; AltName: Full=Beta-2 adrenoreceptor; Short=Beta-2 adrenoceptor;+++[A2N4T7_HUMAN|Unreviewed]SubName: Full=ADRB2 protein {ECO:0000313|EMBL:AAA88014.1};+++[Q9BYZ0_HUMAN|Unreviewed]SubName: Full=Beta-2 adrenergic receptor {ECO:0000313|EMBL:AAG35451.1}; Flags: Fragment;+++[X5DQM5_HUMAN|Unreviewed]SubName: Full=Adrenoceptor beta 2 surface isoform A {ECO:0000313|EMBL:AHW56402.1}; Flags: Fragment;"]
[154661,"'RUNDC3B'",1,8,4.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":6},"IPR004012///RUN domain+++IPR037213///RUN domain superfamily","[RUN3B_HUMAN|Reviewed]RecName: Full=RUN domain-containing protein 3B; AltName: Full=Rap2-binding protein 9; AltName: Full=Rap2-interacting protein 9; Short=RPIP-9;"]
[155185,"'AMZ1'",0,2,1,"04137///Mitophagy - animal+++04022///cGMP-PKG signaling pathway+++05163///Human cytomegalovirus infection+++05200///Pathways in cancer+++04730///Long-term depression+++04072///Phospholipase D signaling pathway+++04810///Regulation of actin cytoskeleton+++04270///Vascular smooth muscle contraction+++04140///Autophagy - animal+++04071///Sphingolipid signaling pathway+++04010///MAPK signaling pathway+++04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0005575///cellular_component","GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding","GO:0006508///proteolysis","IPR012962///Peptidase M54, archaemetzincin+++IPR024079///Metallopeptidase, catalytic domain superfamily","[AMZ1_HUMAN|Reviewed]RecName: Full=Archaemetzincin-1; EC=3.4.-.-; AltName: Full=Archeobacterial metalloproteinase-like protein 1;+++[A4D202_HUMAN|Unreviewed]SubName: Full=Archaelysin family metallopeptidase 1 {ECO:0000313|EMBL:AAI46754.1}; SubName: Full=Archaemetzincin-1, isoform CRA_a {ECO:0000313|EMBL:EAW87269.1}; SubName: Full=KIAA1950 protein {ECO:0000313|EMBL:EAL23959.1}; SubName: Full=cDNA FLJ76739, highly similar to Homo sapiens archaemetzincin-1 (AMZ1), mRNA {ECO:0000313|EMBL:BAF82412.1};"]
[157313,"'CDCA2'",2,3,2.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0005634///nucleus",null,"GO:0007049///cell cycle+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0051301///cell division","IPR029334///Protein phosphatase 1 binding domain+++IPR033064///Cell division cycle-associated protein 2","[CDCA2_HUMAN|Reviewed]RecName: Full=Cell division cycle-associated protein 2; AltName: Full=Recruits PP1 onto mitotic chromatin at anaphase protein; Short=Repo-Man;+++[A8K8Z0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78763 {ECO:0000313|EMBL:BAF85194.1};+++[B7Z5Q5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61606, highly similar to Homo sapiens cell division cycle associated 2 (CDCA2), mRNA {ECO:0000313|EMBL:BAH12991.1};+++[E9PEI0_HUMAN|Unreviewed]SubName: Full=Cell division cycle-associated protein 2 {ECO:0000313|Ensembl:ENSP00000370040};"]
[157855,"'KCNU1'",0,4,2,"04270///Vascular smooth muscle contraction+++04911///Insulin secretion+++04022///cGMP-PKG signaling pathway",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0008076///voltage-gated potassium channel complex","GO:0005267///potassium channel activity+++GO:0015269///calcium-activated potassium channel activity+++GO:0005249///voltage-gated potassium channel activity+++GO:0015271///outward rectifier potassium channel activity+++GO:0060072///large conductance calcium-activated potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005216///ion channel activity","GO:0006811///ion transport+++GO:0035036///sperm-egg recognition+++GO:0055085///transmembrane transport+++GO:0042391///regulation of membrane potential+++GO:0034220///ion transmembrane transport+++GO:0006813///potassium ion transport+++GO:0022414///reproductive process+++GO:0034765///regulation of ion transmembrane transport+++GO:0071805///potassium ion transmembrane transport","IPR005821///Ion transport domain+++IPR027359///Voltage-dependent channel domain superfamily+++IPR003929///Potassium channel, BK, alpha subunit","[KCNU1_HUMAN|Reviewed]RecName: Full=Potassium channel subfamily U member 1; AltName: Full=Calcium-activated potassium channel subunit alpha-3; AltName: Full=Calcium-activated potassium channel, subfamily M subunit alpha-3; AltName: Full=KCa5; AltName: Full=Slowpoke homolog 3;+++[E5RGP7_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily U member 1 {ECO:0000313|Ensembl:ENSP00000429951}; Flags: Fragment;+++[E5RHP1_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily U member 1 {ECO:0000313|Ensembl:ENSP00000428552};+++[E5RJA6_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily U member 1 {ECO:0000313|Ensembl:ENSP00000429149};+++[E5RK72_HUMAN|Unreviewed]SubName: Full=Potassium channel subfamily U member 1 {ECO:0000313|Ensembl:ENSP00000428106};"]
[158326,"'FREM1'",1,1,1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005604///basement membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region","GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding","GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0097094///craniofacial suture morphogenesis+++GO:0007160///cell-matrix adhesion+++GO:0007154///cell communication","IPR001304///C-type lectin-like+++IPR003644///Na-Ca exchanger/integrin-beta4+++IPR016186///C-type lectin-like/link domain superfamily+++IPR039005///CSPG repeat+++IPR038081///CalX-like domain superfamily+++IPR016187///C-type lectin fold+++IPR032825///FRAS1-related extracellular matrix protein 1","[FREM1_HUMAN|Reviewed]RecName: Full=FRAS1-related extracellular matrix protein 1 {ECO:0000305}; AltName: Full=Protein QBRICK; Flags: Precursor;+++[F8WE85_HUMAN|Unreviewed]SubName: Full=FRAS1-related extracellular matrix protein 1 {ECO:0000313|Ensembl:ENSP00000370257};"]
[158880,"'USP51'",23,15,19,null,"H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005694///chromosome","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0042393///histone binding+++GO:0008233///peptidase activity+++GO:0003682///chromatin binding+++GO:0016787///hydrolase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0008234///cysteine-type peptidase activity","GO:0006974///cellular response to DNA damage stimulus+++GO:0016579///protein deubiquitination+++GO:0010564///regulation of cell cycle process+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016578///histone deubiquitination+++GO:0006508///proteolysis+++GO:0006281///DNA repair+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:2001032///regulation of double-strand break repair via nonhomologous end joining","IPR033383///Ubiquitin-specific peptidase 51+++IPR018200///Ubiquitin specific protease, conserved site+++IPR001607///Zinc finger, UBP-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase+++IPR028889///Ubiquitin specific protease domain+++IPR038765///Papain-like cysteine peptidase superfamily","[UBP51_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 51 {ECO:0000303|PubMed:27083998}; EC=3.4.19.12 {ECO:0000269|PubMed:27083998}; AltName: Full=Deubiquitinating enzyme 51; AltName: Full=Ubiquitin thioesterase 51; AltName: Full=Ubiquitin-specific-processing protease 51;+++[A0A1B0GVA6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 51 {ECO:0000313|Ensembl:ENSP00000490435}; Flags: Fragment;"]
[159989,"'DEUP1'",7,3,5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0098536///deuterosome+++GO:0016021///integral component of membrane+++GO:0005814///centriole+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0030030///cell projection organization+++GO:1903251///multi-ciliated epithelial cell differentiation+++GO:0007099///centriole replication+++GO:0098535///de novo centriole assembly involved in multi-ciliated epithelial cell differentiation","IPR029611///Deuterosome assembly protein 1+++IPR031470///Centrosomal protein Cep63/Deup1, N-terminal","[DEUP1_HUMAN|Reviewed]RecName: Full=Deuterosome assembly protein 1 {ECO:0000312|HGNC:HGNC:26344}; AltName: Full=Coiled-coil domain-containing protein 67;+++[A0A087WVI3_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000479457};+++[A0A088AWP1_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000433537};+++[A0A0A0MTD8_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000432111};+++[E9PIY2_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000431946}; Flags: Fragment;+++[E9PLL9_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000433254};+++[E9PLX9_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000435079};+++[E9PMP4_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000433002};+++[E9PPB2_HUMAN|Unreviewed]SubName: Full=Deuterosome assembly protein 1 {ECO:0000313|Ensembl:ENSP00000434635}; Flags: Fragment;"]
[1606,"'DGKA'",2170,2090,2130,"01100///Metabolic pathways+++05231///Choline metabolism in cancer+++01110///Biosynthesis of secondary metabolites+++04072///Phospholipase D signaling pathway+++00561///Glycerolipid metabolism+++00564///Glycerophospholipid metabolism+++04070///Phosphatidylinositol signaling system","H01657///Nephrotic syndrome+++H01726///Membranoproliferative glomerulonephritis",null,"R02240///ATP:1,2-diacylglycerol 3-phosphotransferase   ATP + 1,2-Diacyl-sn-glycerol <=> ADP + Phosphatidate","GO:0005575///cellular_component+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0003951///NAD+ kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0005543///phospholipid binding+++GO:0005509///calcium ion binding+++GO:0016740///transferase activity+++GO:0004143///diacylglycerol kinase activity+++GO:0005524///ATP binding+++GO:0046872///metal ion binding","GO:0008150///biological_process+++GO:0030168///platelet activation+++GO:0035556///intracellular signal transduction+++GO:0016310///phosphorylation+++GO:0046486///glycerolipid metabolic process+++GO:0006654///phosphatidic acid biosynthetic process+++GO:0046339///diacylglycerol metabolic process+++GO:0046834///lipid phosphorylation+++GO:0007165///signal transduction+++GO:0007205///protein kinase C-activating G protein-coupled receptor signaling pathway","IPR011992///EF-hand domain pair+++IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR001206///Diacylglycerol kinase, catalytic domain+++IPR018247///EF-Hand 1, calcium-binding site+++IPR002048///EF-hand domain+++IPR038199///DGK type I, N-terminal domain superfamily+++IPR017438///Inorganic polyphosphate/ATP-NAD kinase, N-terminal+++IPR000756///Diacylglycerol kinase, accessory domain+++IPR037607///Diacylglycerol kinase+++IPR016064///NAD kinase/diacylglycerol kinase-like domain superfamily+++IPR029477///Diacylglycerol kinase type I, N-terminal","[DGKA_HUMAN|Reviewed]RecName: Full=Diacylglycerol kinase alpha; Short=DAG kinase alpha; EC=2.7.1.107; AltName: Full=80 kDa diacylglycerol kinase; AltName: Full=Diglyceride kinase alpha; Short=DGK-alpha;+++[A0A024RB23_HUMAN|Unreviewed]RecName: Full=Diacylglycerol kinase {ECO:0000256|RuleBase:RU361128}; Short=DAG kinase {ECO:0000256|RuleBase:RU361128}; EC=2.7.1.107 {ECO:0000256|RuleBase:RU361128};+++[C9JM35_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000402307}; Flags: Fragment;+++[F8VNZ9_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000446515}; Flags: Fragment;+++[F8VWX8_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000449178}; Flags: Fragment;+++[F8W1H7_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000447050}; Flags: Fragment;+++[F8W1M3_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000447460}; Flags: Fragment;+++[G3V312_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000450977}; Flags: Fragment;+++[G3V327_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000450999}; Flags: Fragment;+++[G3V4E1_HUMAN|Unreviewed]RecName: Full=Diacylglycerol kinase {ECO:0000256|RuleBase:RU361128}; Short=DAG kinase {ECO:0000256|RuleBase:RU361128}; EC=2.7.1.107 {ECO:0000256|RuleBase:RU361128}; Flags: Fragment;+++[G3V4I3_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000451814}; Flags: Fragment;+++[H0YJE7_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|Ensembl:ENSP00000451330}; Flags: Fragment;+++[H0YJH4_HUMAN|Unreviewed]RecName: Full=Diacylglycerol kinase {ECO:0000256|RuleBase:RU361128}; Short=DAG kinase {ECO:0000256|RuleBase:RU361128}; EC=2.7.1.107 {ECO:0000256|RuleBase:RU361128}; Flags: Fragment;+++[O75484_HUMAN|Unreviewed]SubName: Full=Diacylglycerol kinase alpha {ECO:0000313|EMBL:AAC34805.1}; EC=2.7.1.107 {ECO:0000313|EMBL:AAC34805.1};"]
[161176,"'SYNE3'",12,12,12,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0005635///nuclear envelope+++GO:0005791///rough endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005640///nuclear outer membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0034993///meiotic nuclear membrane microtubule tethering complex","GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding","GO:0007097///nuclear migration+++GO:0090150///establishment of protein localization to membrane+++GO:0051647///nucleus localization+++GO:0008360///regulation of cell shape+++GO:0007010///cytoskeleton organization+++GO:0090286///cytoskeletal anchoring at nuclear membrane","IPR030267///Nesprin-3+++IPR018159///Spectrin/alpha-actinin+++IPR012315///KASH domain+++IPR002017///Spectrin repeat","[SYNE3_HUMAN|Reviewed]RecName: Full=Nesprin-3; AltName: Full=KASH domain-containing protein 3; Short=KASH3; AltName: Full=Nuclear envelope spectrin repeat protein 3;+++[G3V533_HUMAN|Unreviewed]SubName: Full=Nesprin-3 {ECO:0000313|Ensembl:ENSP00000452154};+++[Q6P714_HUMAN|Unreviewed]SubName: Full=C14orf49 protein {ECO:0000313|EMBL:AAH61899.1};"]
[161742,"'SPRED1'",230.13,281,255.565,null,"H01986///Legius syndrome+++H00523///Noonan syndrome and related disorders",null,null,"GO:0005901///caveola+++GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0030291///protein serine/threonine kinase inhibitor activity+++GO:0019901///protein kinase binding+++GO:0019902///phosphatase binding+++GO:0005173///stem cell factor receptor binding+++GO:0005515///protein binding","GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0043408///regulation of MAPK cascade+++GO:0016525///negative regulation of angiogenesis+++GO:0043409///negative regulation of MAPK cascade+++GO:0010923///negative regulation of phosphatase activity+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0006469///negative regulation of protein kinase activity+++GO:0007275///multicellular organism development+++GO:0009966///regulation of signal transduction+++GO:0000165///MAPK cascade+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0000188///inactivation of MAPK activity+++GO:0090311///regulation of protein deacetylation","IPR023337///c-Kit-binding domain+++IPR011993///PH-like domain superfamily+++IPR000697///WH1/EVH1 domain+++IPR007875///Sprouty","[SPRE1_HUMAN|Reviewed]RecName: Full=Sprouty-related, EVH1 domain-containing protein 1; Short=Spred-1; Short=hSpred1;+++[H0YMN8_HUMAN|Unreviewed]SubName: Full=Sprouty-related, EVH1 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000453680}; Flags: Fragment;+++[L8EBE5_HUMAN|Unreviewed]SubName: Full=Alternative protein SPRED1 {ECO:0000313|EMBL:CCQ43858.1};"]
[162417,"'NAGS'",9,8,8.5,"01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00220///Arginine biosynthesis+++01230///Biosynthesis of amino acids+++01210///2-Oxocarboxylic acid metabolism","H01032///N-acetylglutamate synthase (NAGS) deficiency+++H01398///Primary hyperammonemic disorders (Urea cycle disorders)",null,"R00259///acetyl-CoA:L-glutamate N-acetyltransferase   Acetyl-CoA + L-Glutamate <=> CoA + N-Acetyl-L-glutamate","GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0003991///acetylglutamate kinase activity+++GO:0103045///methione N-acyltransferase activity+++GO:0034618///arginine binding+++GO:0004042///acetyl-CoA:L-glutamate N-acetyltransferase activity+++GO:0016740///transferase activity+++GO:0016746///transferase activity, transferring acyl groups","GO:0000050///urea cycle+++GO:0006526///arginine biosynthetic process+++GO:0016310///phosphorylation+++GO:0006536///glutamate metabolic process","IPR011243///N-acetylglutamate synthase, animal+++IPR011242///Acetylglutamate kinase ArgB, GNAT domain-containing+++IPR016181///Acyl-CoA N-acyltransferase+++IPR006855///Vertebrate-like NAGS Gcn5-related N-acetyltransferase (GNAT) domain+++IPR036393///Acetylglutamate kinase-like superfamily","[NAGS_HUMAN|Reviewed]RecName: Full=N-acetylglutamate synthase, mitochondrial; EC=2.3.1.1 {ECO:0000269|PubMed:12459178, ECO:0000269|PubMed:23894642, ECO:0000269|PubMed:7126172}; AltName: Full=Amino-acid acetyltransferase; Contains: RecName: Full=N-acetylglutamate synthase long form; Contains: RecName: Full=N-acetylglutamate synthase short form; Contains: RecName: Full=N-acetylglutamate synthase conserved domain form; Flags: Precursor;+++[K7EK11_HUMAN|Unreviewed]SubName: Full=N-acetylglutamate synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000465408}; Flags: Fragment;+++[Q2NKP2_HUMAN|Unreviewed]SubName: Full=NAGS protein {ECO:0000313|EMBL:AAI11714.1}; SubName: Full=cDNA FLJ54171, highly similar to N-acetylglutamate synthase, mitochondrial {ECO:0000313|EMBL:BAG62555.1};"]
[162967,"'ZNF320'",252.91,268.28,260.595,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR017114///C2H2-type Zinc finger protein,  YY-1-like","[ZN320_HUMAN|Reviewed]RecName: Full=Zinc finger protein 320;+++[M0QX96_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 320 {ECO:0000313|Ensembl:ENSP00000468995}; Flags: Fragment;+++[M0QZA2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 320 {ECO:0000313|Ensembl:ENSP00000470403}; Flags: Fragment;+++[M0R0Z8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 320 {ECO:0000313|Ensembl:ENSP00000471548}; Flags: Fragment;+++[M0R1K6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 320 {ECO:0000313|Ensembl:ENSP00000471938}; Flags: Fragment;+++[M0R2L4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 320 {ECO:0000313|Ensembl:ENSP00000472651}; Flags: Fragment;"]
[163087,"'ZNF383'",61,62,61.5,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box","[ZN383_HUMAN|Reviewed]RecName: Full=Zinc finger protein 383;+++[K7EJN0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 383 {ECO:0000313|Ensembl:ENSP00000465246}; Flags: Fragment;+++[K7ELW4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 383 {ECO:0000313|Ensembl:ENSP00000466246};"]
[1635,"'DCTD'",809,703,756,"01100///Metabolic pathways+++00240///Pyrimidine metabolism",null,"M00429///Competence-related DNA transformation transporter","R01663///dCMP aminohydrolase   dCMP + H2O <=> dUMP + Ammonia","GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003824///catalytic activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0004132///dCMP deaminase activity+++GO:0005515///protein binding+++GO:0008270///zinc ion binding","GO:0006231///dTMP biosynthetic process+++GO:0006220///pyrimidine nucleotide metabolic process+++GO:0015949///nucleobase-containing small molecule interconversion+++GO:0008152///metabolic process+++GO:0006226///dUMP biosynthetic process+++GO:0009165///nucleotide biosynthetic process","IPR035105///Deoxycytidylate deaminase domain+++IPR016192///APOBEC/CMP deaminase, zinc-binding+++IPR016193///Cytidine deaminase-like+++IPR002125///Cytidine and deoxycytidylate deaminase domain+++IPR016473///Deoxycytidylate deaminase+++IPR015517///Deoxycytidylate deaminase-related","[DCTD_HUMAN|Reviewed]RecName: Full=Deoxycytidylate deaminase; EC=3.5.4.12; AltName: Full=dCMP deaminase;+++[D6R9P0_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000423498};+++[D6R9S0_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000423182}; Flags: Fragment;+++[D6RAD7_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000422729}; Flags: Fragment;+++[D6RAR9_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000421792}; Flags: Fragment;+++[D6RBJ9_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000422662}; Flags: Fragment;+++[D6RBN2_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000424050}; Flags: Fragment;+++[D6RC36_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000423894}; Flags: Fragment;+++[D6RD72_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000425462};+++[D6RIG3_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000425904};+++[D6RJA9_HUMAN|Unreviewed]SubName: Full=Deoxycytidylate deaminase {ECO:0000313|Ensembl:ENSP00000427282}; Flags: Fragment;"]
[164091,"'PAQR7'",360,359,359.5,null,"H01310///Multi-minicore disease (MmD)+++H00590///Congenital muscular dystrophies (CMD/MDC)+++H00701///Congenital fiber type disproportion (CFTD)",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005496///steroid binding+++GO:0008289///lipid binding+++GO:0038023///signaling receptor activity","GO:0030154///cell differentiation+++GO:0048477///oogenesis+++GO:0007275///multicellular organism development","IPR004254///AdipoR/Haemolysin-III-related","[PAQR7_HUMAN|Reviewed]RecName: Full=Membrane progestin receptor alpha {ECO:0000303|PubMed:23763432}; Short=mPR alpha {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone P4 receptor alpha {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone receptor alpha {ECO:0000303|PubMed:23763432}; AltName: Full=Progesterone and adipoQ receptor family member 7; AltName: Full=Progestin and adipoQ receptor family member 7 {ECO:0000303|PubMed:16044242}; AltName: Full=Progestin and adipoQ receptor family member VII;+++[A1L182_HUMAN|Unreviewed]SubName: Full=PAQR7 protein {ECO:0000313|EMBL:AAI27801.1}; Flags: Fragment;"]
[1643,"'DDB2'",916,879,897.5,"05226///Gastric cancer+++05200///Pathways in cancer+++05217///Basal cell carcinoma+++04120///Ubiquitin mediated proteolysis+++05210///Colorectal cancer+++05225///Hepatocellular carcinoma+++04115///p53 signaling pathway+++05214///Glioma+++05216///Thyroid cancer+++05218///Melanoma+++05223///Non-small cell lung cancer+++05161///Hepatitis B+++05222///Small cell lung cancer+++05224///Breast cancer+++05220///Chronic myeloid leukemia+++03420///Nucleotide excision repair+++05212///Pancreatic cancer+++05213///Endometrial cancer+++05202///Transcriptional misregulation in cancer","H01428///Xeroderma pigmentosum (XP)+++H00403///Disorders of nucleotide excision repair","M00385///Cul4-DDB1-DDB2 complex",null,"GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0030054///cell junction+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0003677///DNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0003684///damaged DNA binding","GO:0016567///protein ubiquitination+++GO:0006281///DNA repair+++GO:0000209///protein polyubiquitination+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0070911///global genome nucleotide-excision repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0043687///post-translational protein modification+++GO:0006290///pyrimidine dimer repair+++GO:0035518///histone H2A monoubiquitination+++GO:0051865///protein autoubiquitination+++GO:0070914///UV-damage excision repair+++GO:0006289///nucleotide-excision repair+++GO:0010224///response to UV-B+++GO:0009411///response to UV+++GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0016579///protein deubiquitination","IPR033312///DNA damage-binding protein 2+++IPR017986///WD40-repeat-containing domain+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR001680///WD40 repeat+++IPR019775///WD40 repeat, conserved site","[DDB2_HUMAN|Reviewed]RecName: Full=DNA damage-binding protein 2; AltName: Full=DDB p48 subunit; Short=DDBb; AltName: Full=Damage-specific DNA-binding protein 2; AltName: Full=UV-damaged DNA-binding protein 2; Short=UV-DDB 2;+++[A0A087WTQ7_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 2 {ECO:0000313|Ensembl:ENSP00000478063};+++[A0A087WV56_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 2 {ECO:0000313|Ensembl:ENSP00000479196}; Flags: Fragment;+++[A0A087WW71_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 2 {ECO:0000313|Ensembl:ENSP00000479994}; Flags: Fragment;+++[A0A087WYT8_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 2 {ECO:0000313|Ensembl:ENSP00000482080}; Flags: Fragment;+++[A0A087X0X5_HUMAN|Unreviewed]SubName: Full=DNA damage-binding protein 2 {ECO:0000313|Ensembl:ENSP00000483718}; Flags: Fragment;"]
[1656,"'DDX6'",594,796,695,"03018///RNA degradation",null,"M00395///Decapping complex",null,"GO:0000792///heterochromatin+++GO:0010494///cytoplasmic stress granule+++GO:0005737///cytoplasm+++GO:0005913///cell-cell adherens junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0097227///sperm annulus+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0001520///outer dense fiber+++GO:0016442///RISC complex+++GO:0016020///membrane+++GO:0061830///concave side of sperm head+++GO:0033391///chromatoid body+++GO:0005730///nucleolus+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0000932///P-body","GO:0005524///ATP binding+++GO:0003724///RNA helicase activity+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0045296///cadherin binding+++GO:0004386///helicase activity+++GO:0016787///hydrolase activity+++GO:0019904///protein domain specific binding","GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0007283///spermatogenesis+++GO:0048515///spermatid differentiation+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0019827///stem cell population maintenance+++GO:0045665///negative regulation of neuron differentiation+++GO:0019074///viral RNA genome packaging","IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR014014///RNA helicase, DEAD-box type, Q motif+++IPR000629///ATP-dependent RNA helicase DEAD-box, conserved site+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR011545///DEAD/DEAH box helicase domain+++IPR001650///Helicase, C-terminal","[DDX6_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX6 {ECO:0000305}; EC=3.6.4.13 {ECO:0000305}; AltName: Full=ATP-dependent RNA helicase p54; AltName: Full=DEAD box protein 6; AltName: Full=Oncogene RCK;+++[B2R858_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93750, Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 (DDX6), mRNA {ECO:0000313|EMBL:BAG36055.1};+++[Q8IV96_HUMAN|Unreviewed]SubName: Full=DDX6 protein {ECO:0000313|EMBL:AAH39826.1}; SubName: Full=Probable ATP-dependent RNA helicase DDX6 {ECO:0000313|Ensembl:ENSP00000483902};"]
[166379,"'BBS12'",76,69,72.5,null,"H00418///Bardet-Biedl syndrome (BBS)",null,null,"GO:0042995///cell projection+++GO:0005929///cilium","GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0045494///photoreceptor cell maintenance+++GO:0051131///chaperone-mediated protein complex assembly+++GO:0045599///negative regulation of fat cell differentiation+++GO:0042073///intraciliary transport+++GO:0042755///eating behavior","IPR027410///TCP-1-like chaperonin intermediate domain superfamily+++IPR027413///GroEL-like equatorial domain superfamily+++IPR002423///Chaperonin Cpn60/TCP-1 family+++IPR027409///GroEL-like apical domain superfamily","[BBS12_HUMAN|Reviewed]RecName: Full=Bardet-Biedl syndrome 12 protein;+++[A0A1B1SMW0_HUMAN|Unreviewed]SubName: Full=Truncated Bardet-Biedl syndrome 12 protein {ECO:0000313|EMBL:ANV22097.1};+++[C9J8H7_HUMAN|Unreviewed]SubName: Full=Bardet-Biedl syndrome 12 protein {ECO:0000313|Ensembl:ENSP00000398912}; Flags: Fragment;"]
[167227,"'DCP2'",60,75,67.5,"03018///RNA degradation",null,"M00395///Decapping complex","R10815///5'-(N7-methylguanosine 5'-triphospho)-[mRNA] N7-methylguanosine-5'-diphosphate phosphohydrolase   m7G(5')pppR-mRNA + H2O <=> N7-Methylguanosine 5'-diphosphate + 5'-Phospho-[mRNA]","GO:0000932///P-body+++GO:0005634///nucleus+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0030054///cell junction+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016442///RISC complex+++GO:0005829///cytosol","GO:0050072///m7G(5')pppN diphosphatase activity+++GO:0016787///hydrolase activity+++GO:0030145///manganese ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0016896///exoribonuclease activity, producing 5'-phosphomonoesters+++GO:0070034///telomerase RNA binding+++GO:0004534///5'-3' exoribonuclease activity","GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0000290///deadenylation-dependent decapping of nuclear-transcribed mRNA+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006402///mRNA catabolic process+++GO:0043488///regulation of mRNA stability+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:1904872///regulation of telomerase RNA localization to Cajal body+++GO:0071044///histone mRNA catabolic process","IPR000086///NUDIX hydrolase domain+++IPR007722///mRNA decapping protein 2, Box A domain+++IPR036189///mRNA decapping protein 2, Box A domain superfamily+++IPR020084///NUDIX hydrolase, conserved site+++IPR015797///NUDIX hydrolase-like domain superfamily","[DCP2_HUMAN|Reviewed]RecName: Full=m7GpppN-mRNA hydrolase {ECO:0000305}; EC=3.6.1.62 {ECO:0000269|PubMed:12486012, ECO:0000269|PubMed:12923261, ECO:0000269|PubMed:21070968}; AltName: Full=Nucleoside diphosphate-linked moiety X motif 20; Short=Nudix motif 20; AltName: Full=mRNA-decapping enzyme 2; Short=hDpc;+++[D6RCL0_HUMAN|Unreviewed]SubName: Full=m7GpppN-mRNA hydrolase {ECO:0000313|Ensembl:ENSP00000427198};+++[H0Y9T5_HUMAN|Unreviewed]SubName: Full=m7GpppN-mRNA hydrolase {ECO:0000313|Ensembl:ENSP00000424982}; Flags: Fragment;"]
[168451,"'THAP5'",139,159,149,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0002020///protease binding","GO:0007049///cell cycle+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045786///negative regulation of cell cycle","IPR006612///THAP-type zinc finger+++IPR038441///THAP-type zinc finger superfamily","[THAP5_HUMAN|Reviewed]RecName: Full=THAP domain-containing protein 5;+++[C9JIH7_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000415841};"]
[168455,"'CCDC71L'",577,626,601.5,{"$nulls":6},"GO:0045600///positive regulation of fat cell differentiation+++GO:0044255///cellular lipid metabolic process","IPR026695///Coiled-coil domain-containing protein 71/71L","[CC71L_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 71L;+++[A0A0C4DGU7_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 71L {ECO:0000313|Ensembl:ENSP00000479540};"]
[169792,"'GLIS3'",226,384,305,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00512///Permanent neonatal diabetes mellitus (PNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR030405///Zinc finger protein GLIS3+++IPR013087///Zinc finger C2H2-type","[GLIS3_HUMAN|Reviewed]RecName: Full=Zinc finger protein GLIS3; AltName: Full=GLI-similar 3; AltName: Full=Zinc finger protein 515;+++[A0A0S2Z649_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 isoform 2 {ECO:0000313|EMBL:ALQ34344.1};+++[A0A0S2Z689_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 isoform 1 {ECO:0000313|EMBL:ALQ34343.1}; Flags: Fragment;+++[A0A0S2Z6Q5_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 isoform 3 {ECO:0000313|EMBL:ALQ34345.1}; Flags: Fragment;+++[A0A2R8YEK9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein GLIS3 {ECO:0000313|Ensembl:ENSP00000495666};+++[F8WEV9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein GLIS3 {ECO:0000313|Ensembl:ENSP00000419914};+++[Q1PHI1_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS22 {ECO:0000313|EMBL:ABE66458.1}; Flags: Fragment;+++[Q1PHI2_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS21 {ECO:0000313|EMBL:ABE66457.1}; Flags: Fragment;+++[Q1PHI3_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS14 {ECO:0000313|EMBL:ABE66450.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS15 {ECO:0000313|EMBL:ABE66451.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS16 {ECO:0000313|EMBL:ABE66452.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS17 {ECO:0000313|EMBL:ABE66453.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS18 {ECO:0000313|EMBL:ABE66454.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS19 {ECO:0000313|EMBL:ABE66455.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS20 {ECO:0000313|EMBL:ABE66456.1}; Flags: Fragment;+++[Q1PHJ0_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS13 {ECO:0000313|EMBL:ABE66449.1}; Flags: Fragment;+++[Q1PHJ1_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS12 {ECO:0000313|EMBL:ABE66448.1}; Flags: Fragment;+++[Q1PHJ2_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS10 {ECO:0000313|EMBL:ABE66446.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS11 {ECO:0000313|EMBL:ABE66447.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS7 {ECO:0000313|EMBL:ABE66443.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS8 {ECO:0000313|EMBL:ABE66444.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS9 {ECO:0000313|EMBL:ABE66445.1}; SubName: Full=Zinc finger protein GLIS3 {ECO:0000313|Ensembl:ENSP00000418005}; Flags: Fragment;+++[Q1PHJ7_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS6 {ECO:0000313|EMBL:ABE66442.1}; Flags: Fragment;+++[Q1PHJ8_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS2 {ECO:0000313|EMBL:ABE66438.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS3 {ECO:0000313|EMBL:ABE66439.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS4 {ECO:0000313|EMBL:ABE66440.1}; SubName: Full=GLIS family zinc finger 3 transcript variant TS5 {ECO:0000313|EMBL:ABE66441.1}; SubName: Full=Zinc finger protein GLIS3 {ECO:0000313|Ensembl:ENSP00000417794}; Flags: Fragment;+++[Q1PHK2_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TE2 {ECO:0000313|EMBL:ABE66437.1}; Flags: Fragment;+++[Q1PHK3_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TE1 {ECO:0000313|EMBL:ABE66436.1}; Flags: Fragment;+++[Q1PHK4_HUMAN|Unreviewed]SubName: Full=GLIS family zinc finger 3 transcript variant TS1 {ECO:0000313|EMBL:ABE66435.1};"]
[170679,"'PSORS1C1'",27,22,24.5,{"$nulls":7},"IPR028206///Psoriasis susceptibility 1 candidate 1","[PS1C1_HUMAN|Reviewed]RecName: Full=Psoriasis susceptibility 1 candidate gene 1 protein; AltName: Full=Protein SEEK1;+++[A0A0C4DGJ2_HUMAN|Unreviewed]SubName: Full=Psoriasis susceptibility 1 candidate gene 1 protein {ECO:0000313|Ensembl:ENSP00000449471};+++[A0A140T8W9_HUMAN|Unreviewed]SubName: Full=Psoriasis susceptibility 1 candidate gene 1 protein {ECO:0000313|Ensembl:ENSP00000365466};+++[A0A1W2PNR1_HUMAN|Unreviewed]SubName: Full=Psoriasis susceptibility 1 candidate gene 1 protein {ECO:0000313|Ensembl:ENSP00000491028};+++[A0A1W2PQG0_HUMAN|Unreviewed]SubName: Full=Psoriasis susceptibility 1 candidate gene 1 protein {ECO:0000313|Ensembl:ENSP00000491714};+++[A0A1W2PRX9_HUMAN|Unreviewed]SubName: Full=Psoriasis susceptibility 1 candidate gene 1 protein {ECO:0000313|Ensembl:ENSP00000492711};+++[D2IYL0_HUMAN|Unreviewed]SubName: Full=PSORS1C1 {ECO:0000313|EMBL:AQY77361.1}; SubName: Full=Psoriasis susceptibility 1 candidate 1 {ECO:0000313|EMBL:AGG40964.1}; SubName: Full=SEEK1 {ECO:0000313|EMBL:ACZ95706.1};+++[Q2L6G9_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 16 {ECO:0000313|EMBL:BAE78626.1}; SubName: Full=PSORS1C1 {ECO:0000313|EMBL:AQY77363.1};+++[Q2M3K9_HUMAN|Unreviewed]SubName: Full=PSORS1C1 protein {ECO:0000313|EMBL:AAI04871.1}; SubName: Full=Psoriasis susceptibility 1 candidate gene 1 protein {ECO:0000313|Ensembl:ENSP00000447158};"]
[171177,"'RHOV'",2,0,1,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0042995///cell projection+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0005829///cytosol+++GO:0030133///transport vesicle+++GO:0015630///microtubule cytoskeleton+++GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0046872///metal ion binding+++GO:0005215///transporter activity+++GO:0003924///GTPase activity+++GO:0008017///microtubule binding+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0019900///kinase binding","GO:0006469///negative regulation of protein kinase activity+++GO:0031122///cytoplasmic microtubule organization+++GO:0017156///calcium ion regulated exocytosis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0008360///regulation of cell shape+++GO:0006611///protein export from nucleus+++GO:0007015///actin filament organization+++GO:0030031///cell projection assembly+++GO:0001933///negative regulation of protein phosphorylation+++GO:0031397///negative regulation of protein ubiquitination+++GO:0060050///positive regulation of protein glycosylation+++GO:0051222///positive regulation of protein transport+++GO:0050821///protein stabilization+++GO:0061024///membrane organization+++GO:0032488///Cdc42 protein signal transduction+++GO:0001578///microtubule bundle formation+++GO:0006897///endocytosis+++GO:0007163///establishment or maintenance of cell polarity+++GO:0022406///membrane docking+++GO:0061025///membrane fusion+++GO:0051259///protein complex oligomerization+++GO:0007266///Rho protein signal transduction+++GO:0030036///actin cytoskeleton organization","IPR003578///Small GTPase Rho+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR005225///Small GTP-binding protein domain+++IPR001806///Small GTPase","[RHOV_HUMAN|Reviewed]RecName: Full=Rho-related GTP-binding protein RhoV; AltName: Full=CDC42-like GTPase 2; AltName: Full=GTP-binding protein-like 2; AltName: Full=Rho GTPase-like protein ARHV; AltName: Full=Wnt-1 responsive Cdc42 homolog 2; Short=WRCH-2;+++[A0A024R9R2_HUMAN|Unreviewed]SubName: Full=Ras homolog gene family, member V, isoform CRA_a {ECO:0000313|EMBL:EAW92460.1};+++[Q05D03_HUMAN|Unreviewed]SubName: Full=RHOV protein {ECO:0000313|EMBL:AAH19353.1}; Flags: Fragment;"]
[1728,"'NQO1'",1285,797.48,1041.24,"05200///Pathways in cancer+++01110///Biosynthesis of secondary metabolites+++05225///Hepatocellular carcinoma+++05418///Fluid shear stress and atherosclerosis+++00130///Ubiquinone and other terpenoid-quinone biosynthesis",null,null,"R03643///NADH:(quinone-acceptor) oxidoreductase   Vitamin K + NADH + H+ <=> Reduced Vitamin K + NAD++++R03816///NADH:phylloquinone oxidoreductase   Phylloquinone + NADH + H+ <=> Phylloquinol + NAD++++R02964///NADH:menaquinone oxidoreductase   Menaquinone + H+ + NADH <=> Menaquinol + NAD+","GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0030425///dendrite+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0004784///superoxide dismutase activity+++GO:0003955///NAD(P)H dehydrogenase (quinone) activity+++GO:0042802///identical protein binding+++GO:0009055///electron transfer activity+++GO:0016491///oxidoreductase activity+++GO:0004128///cytochrome-b5 reductase activity, acting on NAD(P)H+++GO:0003723///RNA binding","GO:1901698///response to nitrogen compound+++GO:0009636///response to toxic substance+++GO:0071248///cellular response to metal ion+++GO:0051602///response to electrical stimulus+++GO:0007271///synaptic transmission, cholinergic+++GO:1904880///response to hydrogen sulfide+++GO:0006521///regulation of cellular amino acid metabolic process+++GO:0006805///xenobiotic metabolic process+++GO:0045471///response to ethanol+++GO:0022900///electron transport chain+++GO:0006809///nitric oxide biosynthetic process+++GO:0043086///negative regulation of catalytic activity+++GO:0006801///superoxide metabolic process+++GO:0007584///response to nutrient+++GO:0043066///negative regulation of apoptotic process+++GO:0055114///oxidation-reduction process+++GO:0019430///removal of superoxide radicals+++GO:0070301///cellular response to hydrogen peroxide+++GO:0006979///response to oxidative stress+++GO:0007568///aging+++GO:0032355///response to estradiol+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0014070///response to organic cyclic compound","IPR029039///Flavoprotein-like superfamily+++IPR003680///Flavodoxin-like fold","[NQO1_HUMAN|Reviewed]RecName: Full=NAD(P)H dehydrogenase [quinone] 1; EC=1.6.5.2; AltName: Full=Azoreductase; AltName: Full=DT-diaphorase; Short=DTD; AltName: Full=Menadione reductase; AltName: Full=NAD(P)H:quinone oxidoreductase 1; AltName: Full=Phylloquinone reductase; AltName: Full=Quinone reductase 1; Short=QR1;+++[B4DLR8_HUMAN|Unreviewed]SubName: Full=NAD(P)H dehydrogenase [quinone] 1 {ECO:0000313|Ensembl:ENSP00000398330}; SubName: Full=cDNA FLJ50573, highly similar to Homo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG59630.1};+++[H3BNV2_HUMAN|Unreviewed]SubName: Full=NAD(P)H dehydrogenase [quinone] 1 {ECO:0000313|Ensembl:ENSP00000455020}; SubName: Full=NAD(P)H dehydrogenase, quinone 1, isoform CRA_a {ECO:0000313|EMBL:EAW83282.1};+++[H3BRK3_HUMAN|Unreviewed]SubName: Full=NAD(P)H dehydrogenase [quinone] 1 {ECO:0000313|Ensembl:ENSP00000456282};+++[L8E9G5_HUMAN|Unreviewed]SubName: Full=Alternative protein NQO1 {ECO:0000313|EMBL:CCQ42998.1};+++[L8EC59_HUMAN|Unreviewed]SubName: Full=Alternative protein NQO1 {ECO:0000313|EMBL:CCQ42997.1};+++[Q3B792_HUMAN|Unreviewed]SubName: Full=NQO1 protein {ECO:0000313|EMBL:AAI07740.1}; Flags: Fragment;"]
[1746,"'DLX2'",3,4,3.5,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003682///chromatin binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003727///single-stranded RNA binding","GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0048706///embryonic skeletal system development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021766///hippocampus development+++GO:0030154///cell differentiation+++GO:0021882///regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0009954///proximal/distal pattern formation+++GO:0021892///cerebral cortex GABAergic interneuron differentiation+++GO:0021772///olfactory bulb development+++GO:0048715///negative regulation of oligodendrocyte differentiation+++GO:0021893///cerebral cortex GABAergic interneuron fate commitment+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0007275///multicellular organism development+++GO:0021544///subpallium development+++GO:0045597///positive regulation of cell differentiation+++GO:1902871///positive regulation of amacrine cell differentiation+++GO:0007420///brain development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0021879///forebrain neuron differentiation+++GO:0051216///cartilage development+++GO:0048755///branching morphogenesis of a nerve","IPR017970///Homeobox, conserved site+++IPR001356///Homeobox domain+++IPR009057///Homeobox-like domain superfamily+++IPR020479///Homeobox domain, metazoa+++IPR022135///Distal-less-like homeobox protein, N-terminal domain+++IPR000047///Helix-turn-helix motif","[DLX2_HUMAN|Reviewed]RecName: Full=Homeobox protein DLX-2;+++[Q53QU7_HUMAN|Unreviewed]SubName: Full=Distal-less homeobox 2 {ECO:0000313|EMBL:EAX11180.1}; SubName: Full=cDNA FLJ75693, highly similar to Homo sapiens distal-less homeo box 2 (DLX2), mRNA {ECO:0000313|EMBL:BAF84056.1};+++[X5D7D8_HUMAN|Unreviewed]SubName: Full=Distal-less homeobox 2 isoform A {ECO:0000313|EMBL:AHW56465.1}; Flags: Fragment;"]
[1773,"'DNASE1'",255.31,264.19,259.75,"05169///Epstein-Barr virus infection+++05203///Viral carcinogenesis+++05164///Influenza A+++04720///Long-term potentiation+++05165///Human papillomavirus infection+++05166///HTLV-I infection+++05211///Renal cell carcinoma+++04110///Cell cycle+++04024///cAMP signaling pathway+++04310///Wnt signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04630///Jak-STAT signaling pathway+++04919///Thyroid hormone signaling pathway+++05215///Prostate cancer+++04330///Notch signaling pathway+++04520///Adherens junction+++04916///Melanogenesis+++05152///Tuberculosis+++04350///TGF-beta signaling pathway+++05016///Huntington's disease+++05206///MicroRNAs in cancer+++04068///FoxO signaling pathway+++05168///Herpes simplex infection+++05161///Hepatitis B+++04140///Autophagy - animal+++05200///Pathways in cancer+++04137///Mitophagy - animal+++04066///HIF-1 signaling pathway+++04922///Glucagon signaling pathway","H01613///Follicular lymphoma+++H00504///Rubinstein-Taybi syndrome+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0070062///extracellular exosome+++GO:0005635///nuclear envelope+++GO:0005634///nucleus+++GO:0005576///extracellular region","GO:0003677///DNA binding+++GO:0004530///deoxyribonuclease I activity+++GO:0003779///actin binding+++GO:0004519///endonuclease activity+++GO:0004536///deoxyribonuclease activity+++GO:0016787///hydrolase activity+++GO:0004518///nuclease activity+++GO:0005515///protein binding","GO:0000737///DNA catabolic process, endonucleolytic+++GO:0002283///neutrophil activation involved in immune response+++GO:0006915///apoptotic process+++GO:0070948///regulation of neutrophil mediated cytotoxicity+++GO:0002673///regulation of acute inflammatory response+++GO:0006308///DNA catabolic process","IPR005135///Endonuclease/exonuclease/phosphatase+++IPR016202///Deoxyribonuclease I+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR033125///Deoxyribonuclease I, conservied site+++IPR018057///Deoxyribonuclease I, active site","[DNAS1_HUMAN|Reviewed]RecName: Full=Deoxyribonuclease-1; EC=3.1.21.1 {ECO:0000269|PubMed:11241278, ECO:0000269|PubMed:2251263, ECO:0000269|PubMed:2277032}; AltName: Full=Deoxyribonuclease I; Short=DNase I; AltName: INN=Dornase alfa; Flags: Precursor;+++[A0A089NFS3_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease 1 {ECO:0000313|EMBL:AIQ84316.1}; SubName: Full=Deoxyribonuclease I {ECO:0000313|EMBL:ANM86073.1}; Flags: Fragment;+++[I3L0Z9_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-1 {ECO:0000313|Ensembl:ENSP00000458467};+++[I3L1N2_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-1 {ECO:0000313|Ensembl:ENSP00000458959}; Flags: Fragment;+++[I3L298_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-1 {ECO:0000313|Ensembl:ENSP00000459507}; Flags: Fragment;+++[I3L4B8_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-1 {ECO:0000313|Ensembl:ENSP00000461129}; Flags: Fragment;+++[I3L4C7_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-1 {ECO:0000313|Ensembl:ENSP00000461153}; Flags: Fragment;+++[I3L4U3_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-1 {ECO:0000313|Ensembl:ENSP00000461527}; Flags: Fragment;+++[I3L530_HUMAN|Unreviewed]SubName: Full=Deoxyribonuclease-1 {ECO:0000313|Ensembl:ENSP00000461745};+++[L8ECC1_HUMAN|Unreviewed]SubName: Full=Alternative protein DNASE1 {ECO:0000313|EMBL:CCQ43307.1};"]
[1793,"'DOCK1'",744,875,809.5,"05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++04510///Focal adhesion+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity+++GO:0017124///SH3 domain binding","GO:0007229///integrin-mediated signaling pathway+++GO:0006915///apoptotic process+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0006911///phagocytosis, engulfment+++GO:0006909///phagocytosis+++GO:0010634///positive regulation of epithelial cell migration+++GO:0016477///cell migration+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0007010///cytoskeleton organization+++GO:0007264///small GTPase mediated signal transduction+++GO:0007596///blood coagulation+++GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0002244///hematopoietic progenitor cell differentiation","IPR026791///Dedicator of cytokinesis+++IPR016024///Armadillo-type fold+++IPR027357///DHR-2 domain+++IPR035892///C2 domain superfamily+++IPR032376///Dedicator of cytokinesis, N-terminal domain+++IPR010703///Dedicator of cytokinesis, C-terminal+++IPR027007///DHR-1 domain+++IPR030717///Dedicator of cytokinesis protein 1+++IPR036028///SH3-like domain superfamily+++IPR001452///SH3 domain","[DOCK1_HUMAN|Reviewed]RecName: Full=Dedicator of cytokinesis protein 1; AltName: Full=180 kDa protein downstream of CRK; Short=DOCK180;+++[A0A096LNH6_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 1 {ECO:0000313|Ensembl:ENSP00000485033};+++[A0A2X0U2H5_HUMAN|Unreviewed]SubName: Full=DOCK1 {ECO:0000313|EMBL:SPT35741.1}; Flags: Fragment;+++[B2RUU3_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 1 {ECO:0000313|EMBL:AAI46858.1};"]
[1812,"'DRD1'",0,2,1,"04024///cAMP signaling pathway+++05030///Cocaine addiction+++04020///Calcium signaling pathway+++05012///Parkinson's disease+++04728///Dopaminergic synapse+++04540///Gap junction+++05031///Amphetamine addiction+++05032///Morphine addiction+++05034///Alcoholism+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0005634///nucleus+++GO:0005887///integral component of plasma membrane+++GO:0097730///non-motile cilium+++GO:0099055///integral component of postsynaptic membrane+++GO:0043197///dendritic spine+++GO:0016020///membrane+++GO:0060170///ciliary membrane+++GO:0012505///endomembrane system+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0098982///GABA-ergic synapse+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0099056///integral component of presynaptic membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0035240///dopamine binding+++GO:0001965///G-protein alpha-subunit binding+++GO:0004952///dopamine neurotransmitter receptor activity+++GO:0001588///dopamine neurotransmitter receptor activity, coupled via Gs","GO:0042417///dopamine metabolic process+++GO:0007191///adenylate cyclase-activating dopamine receptor signaling pathway+++GO:0051968///positive regulation of synaptic transmission, glutamatergic+++GO:0001662///behavioral fear response+++GO:0010628///positive regulation of gene expression+++GO:0043987///histone H3-S10 phosphorylation+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0060292///long-term synaptic depression+++GO:0001661///conditioned taste aversion+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0051584///regulation of dopamine uptake involved in synaptic transmission+++GO:0008542///visual learning+++GO:0042220///response to cocaine+++GO:0007628///adult walking behavior+++GO:0060291///long-term synaptic potentiation+++GO:0007617///mating behavior+++GO:0008306///associative learning+++GO:0043268///positive regulation of potassium ion transport+++GO:1903351///cellular response to dopamine+++GO:0042053///regulation of dopamine metabolic process+++GO:0021853///cerebral cortex GABAergic interneuron migration+++GO:0019226///transmission of nerve impulse+++GO:0035106///operant conditioning+++GO:0048148///behavioral response to cocaine+++GO:0060158///phospholipase C-activating dopamine receptor signaling pathway+++GO:0019228///neuronal action potential+++GO:0042311///vasodilation+++GO:0071870///cellular response to catecholamine stimulus+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0042493///response to drug+++GO:0021766///hippocampus development+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0046959///habituation+++GO:0021756///striatum development+++GO:0007190///activation of adenylate cyclase activity+++GO:0046323///glucose import+++GO:0060134///prepulse inhibition+++GO:0014002///astrocyte development+++GO:0001659///temperature homeostasis+++GO:0007631///feeding behavior+++GO:0015872///dopamine transport+++GO:0001932///regulation of protein phosphorylation+++GO:0030432///peristalsis+++GO:0007626///locomotory behavior+++GO:0007625///grooming behavior+++GO:0046960///sensitization+++GO:0021542///dentate gyrus development+++GO:0001975///response to amphetamine+++GO:0006606///protein import into nucleus+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0030335///positive regulation of cell migration+++GO:0042711///maternal behavior+++GO:0007416///synapse assembly+++GO:0001963///synaptic transmission, dopaminergic+++GO:0007212///dopamine receptor signaling pathway+++GO:0007613///memory+++GO:0007612///learning+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0006936///muscle contraction","IPR000929///Dopamine receptor family+++IPR017452///GPCR, rhodopsin-like, 7TM+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR001413///Dopamine D1 receptor","[DRD1_HUMAN|Reviewed]RecName: Full=D(1A) dopamine receptor; AltName: Full=Dopamine D1 receptor;+++[Q6FH34_HUMAN|Unreviewed]SubName: Full=DRD1 protein {ECO:0000313|EMBL:CAG46720.1}; Flags: Fragment;"]
[183,"'AGT'",19,4,11.5,"04614///Renin-angiotensin system+++04924///Renin secretion","H00575///Renal tubular dysgenesis",null,null,"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0072562///blood microparticle+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0016176///superoxide-generating NADPH oxidase activator activity+++GO:0031703///type 2 angiotensin receptor binding+++GO:0005179///hormone activity+++GO:0008083///growth factor activity+++GO:0048018///receptor ligand activity+++GO:0017080///sodium channel regulator activity+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0031702///type 1 angiotensin receptor binding","GO:0014824///artery smooth muscle contraction+++GO:0019229///regulation of vasoconstriction+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0010536///positive regulation of activation of Janus kinase activity+++GO:0007267///cell-cell signaling+++GO:0051969///regulation of transmission of nerve impulse+++GO:0051403///stress-activated MAPK cascade+++GO:0034104///negative regulation of tissue remodeling+++GO:0061049///cell growth involved in cardiac muscle cell development+++GO:0007200///phospholipase C-activating G protein-coupled receptor signaling pathway+++GO:0035815///positive regulation of renal sodium excretion+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0010629///negative regulation of gene expression+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0048144///fibroblast proliferation+++GO:1903779///regulation of cardiac conduction+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:0002027///regulation of heart rate+++GO:0050729///positive regulation of inflammatory response+++GO:0014873///response to muscle activity involved in regulation of muscle adaptation+++GO:0030308///negative regulation of cell growth+++GO:0045742///positive regulation of epidermal growth factor receptor signaling pathway+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0001822///kidney development+++GO:0008306///associative learning+++GO:0002019///regulation of renal output by angiotensin+++GO:0001974///blood vessel remodeling+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0032930///positive regulation of superoxide anion generation+++GO:0050663///cytokine secretion+++GO:0007263///nitric oxide mediated signal transduction+++GO:1903598///positive regulation of gap junction assembly+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0014061///regulation of norepinephrine secretion+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0007166///cell surface receptor signaling pathway+++GO:1905589///positive regulation of L-arginine import across plasma membrane+++GO:0006883///cellular sodium ion homeostasis+++GO:0003051///angiotensin-mediated drinking behavior+++GO:1902632///positive regulation of membrane hyperpolarization+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0032355///response to estradiol+++GO:0070471///uterine smooth muscle contraction+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0006606///protein import into nucleus+++GO:0045777///positive regulation of blood pressure+++GO:0001558///regulation of cell growth+++GO:0035813///regulation of renal sodium excretion+++GO:0070371///ERK1 and ERK2 cascade+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0033864///positive regulation of NAD(P)H oxidase activity+++GO:0016525///negative regulation of angiogenesis+++GO:0010613///positive regulation of cardiac muscle hypertrophy+++GO:0042311///vasodilation+++GO:0042127///regulation of cell proliferation+++GO:0038166///angiotensin-activated signaling pathway+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity+++GO:0051387///negative regulation of neurotrophin TRK receptor signaling pathway+++GO:0051924///regulation of calcium ion transport+++GO:0007202///activation of phospholipase C activity+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0008217///regulation of blood pressure+++GO:0048659///smooth muscle cell proliferation+++GO:0010873///positive regulation of cholesterol esterification+++GO:1904385///cellular response to angiotensin+++GO:0019216///regulation of lipid metabolic process+++GO:0003331///positive regulation of extracellular matrix constituent secretion+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0010976///positive regulation of neuron projection development+++GO:0002018///renin-angiotensin regulation of aldosterone production+++GO:0007199///G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger+++GO:0002016///regulation of blood volume by renin-angiotensin+++GO:2001275///positive regulation of glucose import in response to insulin stimulus+++GO:0002034///regulation of blood vessel diameter by renin-angiotensin+++GO:0007568///aging+++GO:0048169///regulation of long-term neuronal synaptic plasticity+++GO:0001819///positive regulation of cytokine production+++GO:0010595///positive regulation of endothelial cell migration+++GO:0035106///operant conditioning+++GO:0007565///female pregnancy+++GO:1901201///regulation of extracellular matrix assembly+++GO:0003014///renal system process+++GO:0071260///cellular response to mechanical stimulus+++GO:1905010///positive regulation of L-lysine import across plasma membrane","IPR023795///Serpin, conserved site+++IPR036186///Serpin superfamily+++IPR023796///Serpin domain+++IPR000215///Serpin family+++IPR033834///Angiotensinogen serpin domain+++IPR000227///Angiotensinogen","[ANGT_HUMAN|Reviewed]RecName: Full=Angiotensinogen; AltName: Full=Serpin A8; Contains: RecName: Full=Angiotensin-1; AltName: Full=Angiotensin 1-10; AltName: Full=Angiotensin I; Short=Ang I; Contains: RecName: Full=Angiotensin-2; AltName: Full=Angiotensin 1-8; AltName: Full=Angiotensin II; Short=Ang II; Contains: RecName: Full=Angiotensin-3; AltName: Full=Angiotensin 2-8; AltName: Full=Angiotensin III; Short=Ang III; AltName: Full=Des-Asp[1]-angiotensin II; Contains: RecName: Full=Angiotensin-4; AltName: Full=Angiotensin 3-8; AltName: Full=Angiotensin IV; Short=Ang IV; Contains: RecName: Full=Angiotensin 1-9; Contains: RecName: Full=Angiotensin 1-7; Contains: RecName: Full=Angiotensin 1-5; Contains: RecName: Full=Angiotensin 1-4; Flags: Precursor;+++[B0ZBE2_HUMAN|Unreviewed]SubName: Full=Angiotensinogen (Serpin peptidase inhibitor, clade A, member 8) {ECO:0000313|EMBL:ACA05910.1}; SubName: Full=Angiotensinogen (Serpin peptidase inhibitor, clade A, member 8), isoform CRA_a {ECO:0000313|EMBL:EAW69918.1}; SubName: Full=Fetal-liver predominant transporter 1 {ECO:0000313|EMBL:BAX24569.1};+++[B2R5S1_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ92595, highly similar to Homo sapiens angiotensinogen (serine (or cysteine) proteinaseinhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 8)(AGT), mRNA {ECO:0000313|EMBL:BAG35218.1};"]
[1847,"'DUSP5'",66,61,63.5,"04010///MAPK signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0017017///MAP kinase tyrosine/serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity","GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0016311///dephosphorylation+++GO:0035970///peptidyl-threonine dephosphorylation+++GO:0000188///inactivation of MAPK activity+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006470///protein dephosphorylation","IPR029021///Protein-tyrosine phosphatase-like+++IPR008343///Mitogen-activated protein (MAP) kinase phosphatase+++IPR036873///Rhodanese-like domain superfamily+++IPR000387///Tyrosine specific protein phosphatases domain+++IPR003595///Protein-tyrosine phosphatase, catalytic+++IPR000340///Dual specificity phosphatase, catalytic domain+++IPR001763///Rhodanese-like domain+++IPR020422///Dual specificity protein phosphatase domain+++IPR016130///Protein-tyrosine phosphatase, active site+++IPR024950///Dual specificity phosphatase","[DUS5_HUMAN|Reviewed]RecName: Full=Dual specificity protein phosphatase 5; EC=3.1.3.16 {ECO:0000269|PubMed:7961985}; EC=3.1.3.48 {ECO:0000269|PubMed:7961985}; AltName: Full=Dual specificity protein phosphatase hVH3;"]
[1874,"'E2F4'",1421,1298,1359.5,"04218///Cellular senescence+++04110///Cell cycle+++04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046983///protein dimerization activity+++GO:0008134///transcription factor binding+++GO:0019904///protein domain specific binding+++GO:0003700///DNA-binding transcription factor activity+++GO:1990841///promoter-specific chromatin binding","GO:0008015///blood circulation+++GO:1903251///multi-ciliated epithelial cell differentiation+++GO:0098534///centriole assembly+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0000278///mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0044458///motile cilium assembly+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0002064///epithelial cell development+++GO:0009887///animal organ morphogenesis+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0008361///regulation of cell size+++GO:0006884///cell volume homeostasis+++GO:0030030///cell projection organization+++GO:0051726///regulation of cell cycle+++GO:0042127///regulation of cell proliferation+++GO:0007049///cell cycle+++GO:0060271///cilium assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR032198///E2F transcription factor, CC-MB domain+++IPR037241///E2F-DP heterodimerization region+++IPR028312///Transcription factor E2F4+++IPR003316///E2F/DP family, winged-helix DNA-binding domain+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR015633///E2F Family","[E2F4_HUMAN|Reviewed]RecName: Full=Transcription factor E2F4; Short=E2F-4;+++[A0A024R6W7_HUMAN|Unreviewed]SubName: Full=E2F transcription factor 4, p107/p130-binding, isoform CRA_b {ECO:0000313|EMBL:EAW83096.1};+++[H3BMP3_HUMAN|Unreviewed]SubName: Full=Transcription factor E2F4 {ECO:0000313|Ensembl:ENSP00000454477};+++[H3BTM3_HUMAN|Unreviewed]SubName: Full=Transcription factor E2F4 {ECO:0000313|Ensembl:ENSP00000457239};+++[H3BVE4_HUMAN|Unreviewed]SubName: Full=Transcription factor E2F4 {ECO:0000313|Ensembl:ENSP00000458082};+++[I3L1B6_HUMAN|Unreviewed]SubName: Full=Transcription factor E2F4 {ECO:0000313|Ensembl:ENSP00000458706}; Flags: Fragment;"]
[1901,"'S1PR1'",59,29,44,"04071///Sphingolipid signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04068///FoxO signaling pathway",{"$nulls":3},"GO:0009897///external side of plasma membrane+++GO:0005886///plasma membrane+++GO:0045121///membrane raft+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0005768///endosome+++GO:0031226///intrinsic component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0001664///G protein-coupled receptor binding+++GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0046625///sphingolipid binding","GO:0030155///regulation of cell adhesion+++GO:0007155///cell adhesion+++GO:0031532///actin cytoskeleton reorganization+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0003245///cardiac muscle tissue growth involved in heart morphogenesis+++GO:0019221///cytokine-mediated signaling pathway+++GO:0001955///blood vessel maturation+++GO:0045446///endothelial cell differentiation+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0050927///positive regulation of positive chemotaxis+++GO:0072678///T cell migration+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0016477///cell migration+++GO:0008284///positive regulation of cell proliferation+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0061384///heart trabecula morphogenesis+++GO:0051497///negative regulation of stress fiber assembly+++GO:0030182///neuron differentiation+++GO:0030335///positive regulation of cell migration+++GO:0007165///signal transduction+++GO:0007420///brain development+++GO:0030500///regulation of bone mineralization+++GO:0030032///lamellipodium assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0043547///positive regulation of GTPase activity+++GO:0045124///regulation of bone resorption+++GO:0001525///angiogenesis+++GO:0006935///chemotaxis+++GO:0030595///leukocyte chemotaxis+++GO:0019226///transmission of nerve impulse+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway","IPR004061///Sphingosine 1-phosphate receptor+++IPR017452///GPCR, rhodopsin-like, 7TM+++IPR000987///EDG-1 sphingosine 1-phosphate receptor+++IPR000276///G protein-coupled receptor, rhodopsin-like","[S1PR1_HUMAN|Reviewed]RecName: Full=Sphingosine 1-phosphate receptor 1; Short=S1P receptor 1; Short=S1P1; AltName: Full=Endothelial differentiation G-protein coupled receptor 1; AltName: Full=Sphingosine 1-phosphate receptor Edg-1; Short=S1P receptor Edg-1; AltName: CD_antigen=CD363;"]
[192668,"'CYS1'",31,7,19,null,"H00410///Maturity onset diabetes of the young (MODY)",null,null,"GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0060170///ciliary membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0008285///negative regulation of cell proliferation+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0006366///transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0043065///positive regulation of apoptotic process+++GO:1901653///cellular response to peptide","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[CYS1_HUMAN|Reviewed]RecName: Full=Cystin-1; AltName: Full=Cilia-associated protein;"]
[1948,"'EFNB2'",528,792,660,"04360///Axon guidance","H00458///Craniosynostosis+++H01992///Craniofrontonasal syndrome",null,null,"GO:0005887///integral component of plasma membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0016021///integral component of membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0098978///glutamatergic synapse+++GO:0098685///Schaffer collateral - CA1 synapse","GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0046875///ephrin receptor binding+++GO:0001618///virus receptor activity+++GO:0004713///protein tyrosine kinase activity","GO:0002042///cell migration involved in sprouting angiogenesis+++GO:0016032///viral process+++GO:0031295///T cell costimulation+++GO:0099149///regulation of postsynaptic neurotransmitter receptor internalization+++GO:0007267///cell-cell signaling+++GO:0010977///negative regulation of neuron projection development+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0007155///cell adhesion+++GO:0072178///nephric duct morphogenesis+++GO:0048013///ephrin receptor signaling pathway+++GO:1903849///positive regulation of aorta morphogenesis+++GO:0009653///anatomical structure morphogenesis+++GO:2000727///positive regulation of cardiac muscle cell differentiation+++GO:0099054///presynapse assembly+++GO:0030154///cell differentiation+++GO:0001525///angiogenesis+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0009887///animal organ morphogenesis+++GO:0007411///axon guidance+++GO:0048514///blood vessel morphogenesis+++GO:0050920///regulation of chemotaxis+++GO:0008284///positive regulation of cell proliferation+++GO:0007399///nervous system development+++GO:0007275///multicellular organism development+++GO:0048845///venous blood vessel morphogenesis+++GO:0010839///negative regulation of keratinocyte proliferation+++GO:1901216///positive regulation of neuron death+++GO:0001945///lymph vessel development+++GO:0046718///viral entry into host cell","IPR019765///Ephrin, conserved site+++IPR008972///Cupredoxin+++IPR031328///Ephrin+++IPR001799///Ephrin receptor-binding domain+++IPR034255///Ephrin-B ectodomain","[EFNB2_HUMAN|Reviewed]RecName: Full=Ephrin-B2; AltName: Full=EPH-related receptor tyrosine kinase ligand 5; Short=LERK-5; AltName: Full=HTK ligand; Short=HTK-L; Flags: Precursor;+++[Q2PDH7_HUMAN|Unreviewed]SubName: Full=Ephrin-B2 {ECO:0000313|EMBL:CAD91556.1}; Flags: Fragment;"]
[196051,"'PLPP4'",2217,2563.01,2390.005,"00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++00561///Glycerolipid metabolism",null,null,"R02239///1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase   Phosphatidate + H2O <=> 1,2-Diacyl-sn-glycerol + Orthophosphate","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0042802///identical protein binding+++GO:0008195///phosphatidate phosphatase activity+++GO:0016787///hydrolase activity+++GO:0016791///phosphatase activity","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0046839///phospholipid dephosphorylation+++GO:0001835///blastocyst hatching+++GO:0006644///phospholipid metabolic process","IPR000326///Phosphatidic acid phosphatase type 2/haloperoxidase+++IPR036938///Phosphatidic acid phosphatase type 2/haloperoxidase superfamily+++IPR028668///Phospholipid phosphatase 4","[PLPP4_HUMAN|Reviewed]RecName: Full=Phospholipid phosphatase 4 {ECO:0000312|HGNC:HGNC:23531}; EC=3.1.3.4; AltName: Full=Phosphatidic acid phosphatase type 2 domain-containing protein 1A;+++[A0A0A0MSZ0_HUMAN|Unreviewed]SubName: Full=Phospholipid phosphatase 4 {ECO:0000313|Ensembl:ENSP00000407979}; Flags: Fragment;+++[B7Z3R3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55218, highly similar to Homo sapiens phosphatidic acid phosphatase type 2 domain containing 1A (PPAPDC1A), mRNA {ECO:0000313|EMBL:BAH12299.1};+++[X6R787_HUMAN|Unreviewed]SubName: Full=Phospholipid phosphatase 4 {ECO:0000313|Ensembl:ENSP00000358069};"]
[1965,"'EIF2S1'",701,864,782.5,"05162///Measles+++05168///Herpes simplex infection+++03013///RNA transport+++05164///Influenza A+++04138///Autophagy - yeast+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04141///Protein processing in endoplasmic reticulum+++04210///Apoptosis+++04140///Autophagy - animal+++05160///Hepatitis C",{"$nulls":3},"GO:0044207///translation initiation ternary complex+++GO:0022627///cytosolic small ribosomal subunit+++GO:0097451///glial limiting end-foot+++GO:0005615///extracellular space+++GO:0005850///eukaryotic translation initiation factor 2 complex+++GO:0072562///blood microparticle+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0045202///synapse+++GO:0005829///cytosol+++GO:0005844///polysome+++GO:0005851///eukaryotic translation initiation factor 2B complex+++GO:0010494///cytoplasmic stress granule+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0043614///multi-eIF complex","GO:0045296///cadherin binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003743///translation initiation factor activity+++GO:0043022///ribosome binding+++GO:0000049///tRNA binding","GO:1990928///response to amino acid starvation+++GO:0009967///positive regulation of signal transduction+++GO:1990737///response to manganese-induced endoplasmic reticulum stress+++GO:0007568///aging+++GO:1905098///negative regulation of guanyl-nucleotide exchange factor activity+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0006468///protein phosphorylation+++GO:0006417///regulation of translation+++GO:0055085///transmembrane transport+++GO:0032933///SREBP signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0032057///negative regulation of translational initiation in response to stress+++GO:2000676///positive regulation of type B pancreatic cell apoptotic process+++GO:0034976///response to endoplasmic reticulum stress+++GO:0042255///ribosome assembly+++GO:0034198///cellular response to amino acid starvation+++GO:0034599///cellular response to oxidative stress+++GO:0036499///PERK-mediated unfolded protein response+++GO:0034063///stress granule assembly+++GO:0034644///cellular response to UV+++GO:1901216///positive regulation of neuron death+++GO:0043558///regulation of translational initiation in response to stress+++GO:0034605///cellular response to heat","IPR024054///Translation initiation factor 2, alpha subunit, middle domain superfamily+++IPR012340///Nucleic acid-binding, OB-fold+++IPR003029///S1 domain+++IPR011488///Translation initiation factor 2, alpha subunit+++IPR024055///Translation initiation factor 2, alpha subunit, C-terminal+++IPR022967///RNA-binding domain, S1","[IF2A_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 2 subunit 1; AltName: Full=Eukaryotic translation initiation factor 2 subunit alpha; Short=eIF-2-alpha; Short=eIF-2A; Short=eIF-2alpha;+++[G3V4T5_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2 subunit 1 {ECO:0000313|Ensembl:ENSP00000451975}; Flags: Fragment;+++[H0YJS4_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2 subunit 1 {ECO:0000313|Ensembl:ENSP00000452034}; Flags: Fragment;+++[Q53XC0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa, isoform CRA_a {ECO:0000313|EMBL:EAW80933.1}; SubName: Full=Full-length cDNA clone CS0DL010YH08 of B cells (Ramos cell line) of Homo sapiens (human) {ECO:0000313|EMBL:CAD61953.1}; SubName: Full=cDNA, FLJ92791, Homo sapiens eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (EIF2S1), mRNA {ECO:0000313|EMBL:BAG35351.1};"]
[197131,"'UBR1'",244,323,283.5,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00571///Johanson-Blizzard syndrome",null,null,"GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0000502///proteasome complex","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0070728///leucine binding","GO:0071596///ubiquitin-dependent protein catabolic process via the N-end rule pathway+++GO:0016567///protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030163///protein catabolic process+++GO:0032007///negative regulation of TOR signaling+++GO:0071233///cellular response to leucine","IPR003769///Adaptor protein ClpS, core+++IPR014719///Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR039164///E3 ubiquitin-protein ligase UBR1-like+++IPR003126///Zinc finger, UBR-type","[UBR1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase UBR1; EC=2.3.2.27; AltName: Full=N-recognin-1; AltName: Full=RING-type E3 ubiquitin transferase UBR1; AltName: Full=Ubiquitin-protein ligase E3-alpha-1; AltName: Full=Ubiquitin-protein ligase E3-alpha-I;+++[A0A087WTJ9_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase UBR1 {ECO:0000313|Ensembl:ENSP00000477932};+++[A0A0C4DGM0_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase UBR1 {ECO:0000313|Ensembl:ENSP00000456327}; Flags: Fragment;+++[H3BNQ6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase UBR1 {ECO:0000313|Ensembl:ENSP00000454962};+++[H3BQF8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase UBR1 {ECO:0000313|Ensembl:ENSP00000455759}; Flags: Fragment;+++[H3BS20_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase UBR1 {ECO:0000313|Ensembl:ENSP00000456502};+++[H3BUC4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase UBR1 {ECO:0000313|Ensembl:ENSP00000457573}; Flags: Fragment;+++[H3BUZ4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase UBR1 {ECO:0000313|Ensembl:ENSP00000457879}; Flags: Fragment;+++[L8E998_HUMAN|Unreviewed]SubName: Full=Alternative protein UBR1 {ECO:0000313|EMBL:CCQ43900.1};"]
[1978,"'EIF4EBP1'",1211,1025,1118,"04211///Longevity regulating pathway+++04150///mTOR signaling pathway+++04152///AMPK signaling pathway+++03013///RNA transport+++04012///ErbB signaling pathway+++04066///HIF-1 signaling pathway+++04910///Insulin signaling pathway+++05165///Human papillomavirus infection+++05163///Human cytomegalovirus infection+++05231///Choline metabolism in cancer+++04151///PI3K-Akt signaling pathway+++05221///Acute myeloid leukemia+++01521///EGFR tyrosine kinase inhibitor resistance+++04218///Cellular senescence",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0008190///eukaryotic initiation factor 4E binding+++GO:0005515///protein binding+++GO:0030371///translation repressor activity","GO:0008286///insulin receptor signaling pathway+++GO:0045947///negative regulation of translational initiation+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0017148///negative regulation of translation+++GO:0031929///TOR signaling+++GO:0006417///regulation of translation+++GO:0002192///IRES-dependent translational initiation of linear mRNA","IPR037582///Eukaryotic translation initiation factor 4E-binding protein 1+++IPR008606///Eukaryotic translation initiation factor 4E binding","[4EBP1_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 4E-binding protein 1; Short=4E-BP1; Short=eIF4E-binding protein 1; AltName: Full=Phosphorylated heat- and acid-stable protein regulated by insulin 1; Short=PHAS-I;"]
[199699,"'DAND5'",4.02,7.5,5.76,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005575///cellular_component+++GO:0005576///extracellular region+++GO:0032993///protein-DNA complex+++GO:0000790///nuclear chromatin+++GO:0005615///extracellular space+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0017053///transcriptional repressor complex","GO:0005515///protein binding+++GO:0043425///bHLH transcription factor binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0016015///morphogen activity+++GO:0008022///protein C-terminus binding+++GO:0046872///metal ion binding+++GO:0071837///HMG box domain binding+++GO:0003676///nucleic acid binding+++GO:0003690///double-stranded DNA binding+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0070491///repressing transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0044212///transcription regulatory region DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003674///molecular_function+++GO:0042826///histone deacetylase binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding","GO:0023019///signal transduction involved in regulation of gene expression+++GO:0048511///rhythmic process+++GO:0035582///sequestering of BMP in extracellular matrix+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016032///viral process+++GO:0003140///determination of left/right asymmetry in lateral mesoderm+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0017015///regulation of transforming growth factor beta receptor signaling pathway+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0045540///regulation of cholesterol biosynthetic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0100057///regulation of phenotypic switching by transcription from RNA polymerase II promoter+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0045766///positive regulation of angiogenesis+++GO:0032869///cellular response to insulin stimulus+++GO:0007565///female pregnancy+++GO:0038101///sequestering of nodal from receptor via nodal binding+++GO:1900108///negative regulation of nodal signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0003281///ventricular septum development+++GO:0061371///determination of heart left/right asymmetry+++GO:1900176///negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry+++GO:0006355///regulation of transcription, DNA-templated+++GO:1904828///positive regulation of hydrogen sulfide biosynthetic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0010469///regulation of signaling receptor activity+++GO:0033194///response to hydroperoxide+++GO:0003283///atrial septum development","IPR004133///DAN+++IPR029034///Cystine-knot cytokine+++IPR016860///Cerberus","[DAND5_HUMAN|Reviewed]RecName: Full=DAN domain family member 5; AltName: Full=Cerberus-like protein 2; Short=Cerl-2; AltName: Full=Cysteine knot superfamily 1, BMP antagonist 3; AltName: Full=Gremlin-3; Flags: Precursor;+++[B2R4Y6_HUMAN|Unreviewed]SubName: Full=Sp1 transcription factor, isoform CRA_a {ECO:0000313|EMBL:EAW96698.1}; SubName: Full=cDNA, FLJ92269 {ECO:0000313|EMBL:BAG34933.1};+++[H3BUU5_HUMAN|Unreviewed]SubName: Full=Transcription factor Sp1 {ECO:0000313|Ensembl:ENSP00000457804}; Flags: Fragment;+++[H3BVI2_HUMAN|Unreviewed]SubName: Full=Transcription factor Sp1 {ECO:0000313|Ensembl:ENSP00000458133}; Flags: Fragment;+++[K7EQF6_HUMAN|Unreviewed]SubName: Full=DAN domain family member 5 {ECO:0000313|Ensembl:ENSP00000467806}; SubName: Full=DAN domain family, member 5, isoform CRA_b {ECO:0000313|EMBL:EAW84337.1};+++[L8E7F4_HUMAN|Unreviewed]SubName: Full=Alternative protein SP1 {ECO:0000313|EMBL:CCQ43200.1};+++[Q15403_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific protein {ECO:0000313|EMBL:AAA66498.1}; Flags: Fragment;"]
[199953,"'TMEM201'",309,361,335,{"$nulls":4},"GO:0005639///integral component of nuclear inner membrane+++GO:0031965///nuclear membrane+++GO:0005737///cytoplasm+++GO:0032541///cortical endoplasmic reticulum+++GO:0031616///spindle pole centrosome+++GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0000922///spindle pole+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016021///integral component of membrane+++GO:0005856///cytoskeleton","GO:0005521///lamin binding+++GO:0005515///protein binding+++GO:0051015///actin filament binding","GO:0010761///fibroblast migration+++GO:0051642///centrosome localization+++GO:0006998///nuclear envelope organization+++GO:0007097///nuclear migration+++GO:0030473///nuclear migration along microtubule+++GO:0090435///protein localization to nuclear envelope","IPR040041///Transmembrane protein 201+++IPR018861///Transmembrane protein 201, C-terminal+++IPR018617///Ima1, N-terminal domain","[TM201_HUMAN|Reviewed]RecName: Full=Transmembrane protein 201; AltName: Full=Spindle-associated membrane protein 1;+++[H0Y4R5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 201 {ECO:0000313|Ensembl:ENSP00000393626}; Flags: Fragment;+++[H0Y994_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 201 {ECO:0000313|Ensembl:ENSP00000423430}; Flags: Fragment;"]
[200185,"'KRTCAP2'",1563,1365,1464,"04360///Axon guidance+++04010///MAPK signaling pathway+++04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway+++04014///Ras signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0008250///oligosaccharyltransferase complex+++GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane","GO:0003674///molecular_function","GO:0042543///protein N-linked glycosylation via arginine+++GO:0006486///protein glycosylation","IPR018614///Keratinocyte-associated protein 2","[KTAP2_HUMAN|Reviewed]RecName: Full=Keratinocyte-associated protein 2; Short=KCP-2;"]
[200523,"'TEX37'",0,2,1,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding",null,"IPR029361///Testis-expressed sequence 37 protein","[TEX37_HUMAN|Reviewed]RecName: Full=Testis-expressed sequence 37 protein; AltName: Full=Testis-specific conserved protein of 21 kDa;+++[A0A140VK60_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 93mP {ECO:0000313|EMBL:AEE61197.1};"]
[2009,"'EML1'",250,281,265.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex+++GO:0097431///mitotic spindle pole+++GO:1990023///mitotic spindle midzone+++GO:0005856///cytoskeleton+++GO:0015630///microtubule cytoskeleton+++GO:0005874///microtubule","GO:0005515///protein binding+++GO:0015631///tubulin binding+++GO:0005509///calcium ion binding+++GO:0008017///microtubule binding","GO:0002244///hematopoietic progenitor cell differentiation+++GO:0007420///brain development+++GO:0007052///mitotic spindle organization+++GO:0007405///neuroblast proliferation+++GO:0000226///microtubule cytoskeleton organization","IPR005108///HELP+++IPR017986///WD40-repeat-containing domain+++IPR001680///WD40 repeat+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR011047///Quinoprotein alcohol dehydrogenase-like superfamily","[EMAL1_HUMAN|Reviewed]RecName: Full=Echinoderm microtubule-associated protein-like 1; Short=EMAP-1; Short=HuEMAP-1;+++[F8W717_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000327384};+++[G3V3J1_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451269};+++[G3V3N9_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451346}; Flags: Fragment;+++[G3V497_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451669}; Flags: Fragment;+++[G3V4H6_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451805}; Flags: Fragment;+++[G3V4U5_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451991}; Flags: Fragment;+++[G3V500_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452089}; Flags: Fragment;+++[G3V538_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452160}; Flags: Fragment;+++[G3V5C8_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452292}; Flags: Fragment;+++[H0YJD8_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451288}; Flags: Fragment;+++[H0YJK4_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000451706}; Flags: Fragment;+++[H0YJS9_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452063}; Flags: Fragment;+++[H0YJY3_HUMAN|Unreviewed]SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000452474}; Flags: Fragment;"]
[201229,"'LYRM9'",81,83.83,82.415,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane",null,null,"IPR008011///Complex 1 LYR protein","[LYRM9_HUMAN|Reviewed]RecName: Full=LYR motif-containing protein 9;+++[D6RAR2_HUMAN|Unreviewed]SubName: Full=LYR motif-containing protein 9 {ECO:0000313|Ensembl:ENSP00000421807};+++[D6RFL2_HUMAN|Unreviewed]SubName: Full=LYR motif-containing protein 9 {ECO:0000313|Ensembl:ENSP00000426554};+++[J3QLB4_HUMAN|Unreviewed]SubName: Full=LYR motif-containing protein 9 {ECO:0000313|Ensembl:ENSP00000463472}; Flags: Fragment;"]
[201514,"'ZNF584'",146.45,133.18,139.815,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily","[ZN584_HUMAN|Reviewed]RecName: Full=Zinc finger protein 584;+++[B4DQS1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57563, moderately similar to Zinc finger protein 584 {ECO:0000313|EMBL:BAG61033.1};+++[F6W0P0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000320731};+++[M0QZA3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000470404};+++[M0R0A3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000471105};+++[M0R2W6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000472853};+++[M0R3F5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 584 {ECO:0000313|Ensembl:ENSP00000473184}; Flags: Fragment;+++[Q8WVQ2_HUMAN|Unreviewed]SubName: Full=ZNF584 protein {ECO:0000313|EMBL:AAH17651.1}; Flags: Fragment;"]
[201931,"'TMEM192'",255.48,191,223.24,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0005770///late endosome+++GO:0005764///lysosome+++GO:0005768///endosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0042803///protein homodimerization activity",null,"IPR029399///TMEM192 family","[TM192_HUMAN|Reviewed]RecName: Full=Transmembrane protein 192;+++[D6RAZ6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 192 {ECO:0000313|Ensembl:ENSP00000424590}; Flags: Fragment;"]
[202374,"'STK32A'",7,11,9,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0018105///peptidyl-serine phosphorylation+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation","IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain","[ST32A_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 32A; EC=2.7.11.1; AltName: Full=Yet another novel kinase 1;+++[B7Z9H7_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 32A {ECO:0000313|Ensembl:ENSP00000381535}; SubName: Full=cDNA, FLJ78841, highly similar to Serine/threonine-protein kinase 32A {ECO:0000313|EMBL:BAH14313.1};"]
[203100,"'HTRA4'",24,15,19.5,{"$nulls":4},"GO:0005576///extracellular region","GO:0004175///endopeptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0005520///insulin-like growth factor binding+++GO:0016787///hydrolase activity","GO:0001558///regulation of cell growth+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0006508///proteolysis","IPR002350///Kazal domain+++IPR036034///PDZ superfamily+++IPR001940///Peptidase S1C+++IPR009003///Peptidase S1, PA clan+++IPR000867///Insulin-like growth factor-binding protein, IGFBP+++IPR001478///PDZ domain+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR036058///Kazal domain superfamily","[HTRA4_HUMAN|Reviewed]RecName: Full=Serine protease HTRA4; EC=3.4.21.-; AltName: Full=High-temperature requirement factor A4; Flags: Precursor;"]
[2035,"'EPB41'",248.05,356.72,302.385,null,"H00231///Hereditary elliptocytosis (HE)+++H00773///Autosomal dominant mental retardation",null,null,"GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0005938///cell cortex+++GO:0005886///plasma membrane+++GO:0014731///spectrin-associated cytoskeleton+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0099738///cell cortex region+++GO:0005856///cytoskeleton+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005829///cytosol+++GO:0030863///cortical cytoskeleton+++GO:0016021///integral component of membrane","GO:0005545///1-phosphatidylinositol binding+++GO:0005516///calmodulin binding+++GO:0051219///phosphoprotein binding+++GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding+++GO:0030507///spectrin binding+++GO:0047485///protein N-terminus binding+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0005200///structural constituent of cytoskeleton","GO:0031032///actomyosin structure organization+++GO:0030036///actin cytoskeleton organization+++GO:0032092///positive regulation of protein binding+++GO:1904778///positive regulation of protein localization to cell cortex+++GO:0051301///cell division+++GO:0008360///regulation of cell shape+++GO:0030866///cortical actin cytoskeleton organization+++GO:0007049///cell cycle+++GO:0065003///protein-containing complex assembly","IPR000798///Ezrin/radixin/moesin-like+++IPR029071///Ubiquitin-like domain superfamily+++IPR019747///FERM conserved site+++IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR018980///FERM, C-terminal PH-like domain+++IPR014847///FERM adjacent (FA)+++IPR021187///Band 4.1 protein, chordates+++IPR019749///Band 4.1 domain+++IPR018979///FERM, N-terminal+++IPR011993///PH-like domain superfamily+++IPR000299///FERM domain+++IPR019748///FERM central domain+++IPR035963///FERM superfamily, second domain+++IPR007477///SAB domain+++IPR008379///Band 4.1, C-terminal","[41_HUMAN|Reviewed]RecName: Full=Protein 4.1; Short=P4.1; AltName: Full=4.1R; AltName: Full=Band 4.1; AltName: Full=EPB4.1;+++[A0A1B0GWG0_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000490911}; Flags: Fragment;+++[A0A2R8Y420_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000493575};+++[A0A2R8Y4N6_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000493958}; Flags: Fragment;+++[A0A2R8Y570_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000494244};+++[A0A2R8Y5C8_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000494357}; Flags: Fragment;+++[A0A2R8Y5G2_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000494435};+++[A0A2R8Y5Z6_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000494945};+++[A0A2R8Y6D0_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000495138};+++[A0A2R8Y6G5_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000495300};+++[A0A2R8Y6T6_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000495763}; Flags: Fragment;+++[A0A2R8Y783_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000496077}; Flags: Fragment;+++[A0A2R8Y7N0_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000496138};+++[A0A2R8Y7Y3_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000496326};+++[A0A2R8YCW8_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000494042};+++[A0A2R8YD30_HUMAN|Unreviewed]SubName: Full=Erythrocyte membrane protein band 4.1 (Elliptocytosis 1, RH-linked), isoform CRA_e {ECO:0000313|EMBL:EAX07666.1}; SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000494212};+++[A0A2R8YFR9_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000496675}; Flags: Fragment;+++[A0A2R8YFU8_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000496751};+++[A0A2U3TZH6_HUMAN|Unreviewed]SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000317597};+++[Q1WWM3_HUMAN|Unreviewed]SubName: Full=EPB41 protein {ECO:0000313|EMBL:AAI14451.1}; Flags: Fragment;+++[Q29RX4_HUMAN|Unreviewed]SubName: Full=EPB41 protein {ECO:0000313|EMBL:AAI13842.1}; Flags: Fragment;+++[Q4VB86_HUMAN|Unreviewed]SubName: Full=EPB41 protein {ECO:0000313|EMBL:AAH96105.2}; SubName: Full=Protein 4.1 {ECO:0000313|Ensembl:ENSP00000348397};+++[Q4VB87_HUMAN|Unreviewed]SubName: Full=EPB41 protein {ECO:0000313|EMBL:AAH96104.1}; Flags: Fragment;+++[Q59F12_HUMAN|Unreviewed]SubName: Full=Protein 4.1 variant {ECO:0000313|EMBL:BAD92886.1}; Flags: Fragment;"]
[2045,"'EPHA7'",1,6,3.5,"04360///Axon guidance",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0031594///neuromuscular junction+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0005737///cytoplasm+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0043235///receptor complex+++GO:0030425///dendrite","GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0005003///ephrin receptor activity+++GO:0004713///protein tyrosine kinase activity+++GO:0045499///chemorepellent activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0005005///transmembrane-ephrin receptor activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0008046///axon guidance receptor activity+++GO:0005004///GPI-linked ephrin receptor activity+++GO:0016301///kinase activity+++GO:0046875///ephrin receptor binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0016740///transferase activity","GO:0099175///regulation of postsynapse organization+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0051964///negative regulation of synapse assembly+++GO:0016310///phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0048755///branching morphogenesis of a nerve+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0001934///positive regulation of protein phosphorylation+++GO:0030154///cell differentiation+++GO:0072178///nephric duct morphogenesis+++GO:0006915///apoptotic process+++GO:0031290///retinal ganglion cell axon guidance+++GO:0007399///nervous system development+++GO:0006468///protein phosphorylation+++GO:0031952///regulation of protein autophosphorylation+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0043066///negative regulation of apoptotic process+++GO:0048671///negative regulation of collateral sprouting+++GO:0050919///negative chemotaxis+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0050730///regulation of peptidyl-tyrosine phosphorylation+++GO:0048013///ephrin receptor signaling pathway+++GO:0007420///brain development+++GO:0009968///negative regulation of signal transduction+++GO:0022407///regulation of cell-cell adhesion+++GO:0043065///positive regulation of apoptotic process+++GO:0007275///multicellular organism development","IPR003961///Fibronectin type III+++IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR027936///Ephrin receptor, transmembrane domain+++IPR016257///Ephrin receptor type-A /type-B+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR036116///Fibronectin type III superfamily+++IPR001660///Sterile alpha motif domain+++IPR013783///Immunoglobulin-like fold+++IPR000719///Protein kinase domain+++IPR001426///Tyrosine-protein kinase, receptor class V, conserved site+++IPR020635///Tyrosine-protein kinase, catalytic domain+++IPR001090///Ephrin receptor ligand binding domain+++IPR008979///Galactose-binding-like domain superfamily+++IPR034283///Ephrin type-A receptor 7, ligand binding domain+++IPR011009///Protein kinase-like domain superfamily+++IPR011641///Tyrosine-protein kinase ephrin type A/B receptor-like+++IPR008266///Tyrosine-protein kinase, active site+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain","[EPHA7_HUMAN|Reviewed]RecName: Full=Ephrin type-A receptor 7; EC=2.7.10.1; AltName: Full=EPH homology kinase 3; Short=EHK-3; AltName: Full=EPH-like kinase 11; Short=EK11; Short=hEK11; Flags: Precursor;+++[L8EAA4_HUMAN|Unreviewed]SubName: Full=Alternative protein EPHA7 {ECO:0000313|EMBL:CCQ43263.1};"]
[205428,"'C3orf58'",190,272,231,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0005576///extracellular region+++GO:0030126///COPI vesicle coat+++GO:0005794///Golgi apparatus+++GO:0005615///extracellular space+++GO:0030137///COPI-coated vesicle+++GO:0031410///cytoplasmic vesicle","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding","GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0034392///negative regulation of smooth muscle cell apoptotic process+++GO:0060038///cardiac muscle cell proliferation","IPR022049///FAM69, protein-kinase domain+++IPR020519///Deleted in autism protein 1-like","[DIA1_HUMAN|Reviewed]RecName: Full=Deleted in autism protein 1; AltName: Full=Golgi Protein of 49 kDa; Short=GoPro49; AltName: Full=Hypoxia and AKT-induced stem cell factor; Short=HASF; Flags: Precursor;+++[B3KTD4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38081 fis, clone CTONG2016217 {ECO:0000313|EMBL:BAG53046.1};+++[C9JY09_HUMAN|Unreviewed]SubName: Full=Deleted in autism protein 1 {ECO:0000313|Ensembl:ENSP00000419947}; Flags: Fragment;+++[E7ET39_HUMAN|Unreviewed]SubName: Full=Deleted in autism protein 1 {ECO:0000313|Ensembl:ENSP00000390796};+++[Q9H325_HUMAN|Unreviewed]SubName: Full=B5R-1S peptide {ECO:0000313|EMBL:AAG40567.1};"]
[2065,"'ERBB3'",1,2,1.5,"05206///MicroRNAs in cancer+++04151///PI3K-Akt signaling pathway+++05205///Proteoglycans in cancer+++04010///MAPK signaling pathway+++04020///Calcium signaling pathway+++04012///ErbB signaling pathway+++01521///EGFR tyrosine kinase inhibitor resistance","H00408///Type I diabetes mellitus+++H00865///Lethal congenital contractural syndrome (LCCS)",null,null,"GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0043235///receptor complex+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane+++GO:0009925///basal plasma membrane+++GO:0005576///extracellular region+++GO:0016324///apical plasma membrane+++GO:0016328///lateral plasma membrane+++GO:0005886///plasma membrane+++GO:0005615///extracellular space","GO:0046982///protein heterodimerization activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0038132///neuregulin binding+++GO:0004672///protein kinase activity+++GO:0042802///identical protein binding+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0016301///kinase activity+++GO:0042803///protein homodimerization activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0019838///growth factor binding+++GO:0005524///ATP binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0038131///neuregulin receptor activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0030296///protein tyrosine kinase activator activity+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0016740///transferase activity+++GO:0004713///protein tyrosine kinase activity","GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0007422///peripheral nervous system development+++GO:0006468///protein phosphorylation+++GO:0010628///positive regulation of gene expression+++GO:0014037///Schwann cell differentiation+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0043066///negative regulation of apoptotic process+++GO:0051402///neuron apoptotic process+++GO:0070886///positive regulation of calcineurin-NFAT signaling cascade+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030154///cell differentiation+++GO:0055025///positive regulation of cardiac muscle tissue development+++GO:0021545///cranial nerve development+++GO:0003197///endocardial cushion development+++GO:0042060///wound healing+++GO:0042127///regulation of cell proliferation+++GO:0007507///heart development+++GO:0007165///signal transduction+++GO:0009968///negative regulation of signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0000165///MAPK cascade+++GO:0016310///phosphorylation+++GO:0038128///ERBB2 signaling pathway+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0051048///negative regulation of secretion+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0007162///negative regulation of cell adhesion+++GO:2000145///regulation of cell motility","IPR032778///Growth factor receptor domain 4+++IPR016245///Tyrosine protein kinase, EGF/ERB/XmrK receptor+++IPR036941///Receptor L-domain superfamily+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR006211///Furin-like cysteine-rich domain+++IPR000494///Receptor L-domain+++IPR006212///Furin-like repeat+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily","[ERBB3_HUMAN|Reviewed]RecName: Full=Receptor tyrosine-protein kinase erbB-3; EC=2.7.10.1; AltName: Full=Proto-oncogene-like protein c-ErbB-3; AltName: Full=Tyrosine kinase-type cell surface receptor HER3; Flags: Precursor;+++[A0A024RB84_HUMAN|Unreviewed]SubName: Full=V-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (Avian), isoform CRA_a {ECO:0000313|EMBL:EAW96880.1};+++[A0A2R8Y6T4_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000495453}; Flags: Fragment;+++[B3KWG5_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000448729}; SubName: Full=cDNA FLJ43038 fis, clone BRTHA3002955, highly similar to Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|EMBL:BAG54127.1};+++[B4DGQ7_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000448483}; SubName: Full=cDNA FLJ59207, highly similar to Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|EMBL:BAG57868.1};+++[F8VRI5_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000448671};+++[F8VRL0_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000448636}; Flags: Fragment;+++[F8VW48_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000449138}; Flags: Fragment;+++[F8VW56_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000449129};+++[F8VX90_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000449713}; Flags: Fragment;+++[F8VYK4_HUMAN|Unreviewed]SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000448946}; Flags: Fragment;+++[O75810_HUMAN|Unreviewed]SubName: Full=ErbB-3 R1 {ECO:0000313|EMBL:AAC39857.1}; Flags: Fragment;+++[O75811_HUMAN|Unreviewed]SubName: Full=ErbB-3 R2 {ECO:0000313|EMBL:AAC39858.1}; Flags: Fragment;+++[O75812_HUMAN|Unreviewed]SubName: Full=ErbB-3 R31 {ECO:0000313|EMBL:AAC39859.1}; SubName: Full=Receptor tyrosine-protein kinase erbB-3 {ECO:0000313|Ensembl:ENSP00000482073}; Flags: Fragment;+++[O75813_HUMAN|Unreviewed]SubName: Full=ErbB-3 R35 {ECO:0000313|EMBL:AAC39860.1}; Flags: Fragment;+++[Q9NNX2_HUMAN|Unreviewed]SubName: Full=ErbB-3 {ECO:0000313|EMBL:AAF86628.1}; Flags: Fragment;+++[Q9NNX3_HUMAN|Unreviewed]SubName: Full=ErbB-3 {ECO:0000313|EMBL:AAF86627.1}; Flags: Fragment;"]
[208,"'AKT2'",2550,2640,2595,"05161///Hepatitis B+++04611///Platelet activation+++04024///cAMP signaling pathway+++04140///Autophagy - animal+++05163///Human cytomegalovirus infection+++05145///Toxoplasmosis+++05205///Proteoglycans in cancer+++04012///ErbB signaling pathway+++05160///Hepatitis C+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04919///Thyroid hormone signaling pathway+++04922///Glucagon signaling pathway+++05164///Influenza A+++04151///PI3K-Akt signaling pathway+++04212///Longevity regulating pathway - worm+++04668///TNF signaling pathway+++04210///Apoptosis+++04370///VEGF signaling pathway+++04664///Fc epsilon RI signaling pathway+++05169///Epstein-Barr virus infection+++04620///Toll-like receptor signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04910///Insulin signaling pathway+++05231///Choline metabolism in cancer+++05210///Colorectal cancer+++05418///Fluid shear stress and atherosclerosis+++04071///Sphingolipid signaling pathway+++04062///Chemokine signaling pathway+++04380///Osteoclast differentiation+++04066///HIF-1 signaling pathway+++04625///C-type lectin receptor signaling pathway+++04213///Longevity regulating pathway - multiple species+++04917///Prolactin signaling pathway+++04510///Focal adhesion+++04068///FoxO signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04920///Adipocytokine signaling pathway+++04014///Ras signaling pathway+++05152///Tuberculosis+++04218///Cellular senescence+++01522///Endocrine resistance+++04371///Apelin signaling pathway+++05222///Small cell lung cancer+++05230///Central carbon metabolism in cancer+++04931///Insulin resistance+++04728///Dopaminergic synapse+++05200///Pathways in cancer+++04926///Relaxin signaling pathway+++04150///mTOR signaling pathway+++04630///Jak-STAT signaling pathway+++01524///Platinum drug resistance+++05213///Endometrial cancer+++05218///Melanoma+++04152///AMPK signaling pathway+++05214///Glioma+++05142///Chagas disease (American trypanosomiasis)+++04933///AGE-RAGE signaling pathway in diabetic complications+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04915///Estrogen signaling pathway+++04550///Signaling pathways regulating pluripotency of stem cells+++05215///Prostate cancer+++04022///cGMP-PKG signaling pathway+++05162///Measles+++05221///Acute myeloid leukemia+++05220///Chronic myeloid leukemia+++04072///Phospholipase D signaling pathway+++04211///Longevity regulating pathway+++04725///Cholinergic synapse+++05212///Pancreatic cancer+++05226///Gastric cancer+++01521///EGFR tyrosine kinase inhibitor resistance+++05166///HTLV-I infection+++04666///Fc gamma R-mediated phagocytosis+++04660///T cell receptor signaling pathway+++05211///Renal cell carcinoma+++04973///Carbohydrate digestion and absorption+++04722///Neurotrophin signaling pathway+++05225///Hepatocellular carcinoma+++04010///MAPK signaling pathway+++05223///Non-small cell lung cancer+++04662///B cell receptor signaling pathway+++04923///Regulation of lipolysis in adipocytes+++04015///Rap1 signaling pathway+++05165///Human papillomavirus infection+++05224///Breast cancer","H01556///Meningioma+++H00420///Familial partial lipodystrophy (FPL)+++H01649///Schizophrenia+++H01885///Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome (MPPH)+++H00027///Ovarian cancer+++H01909///Hypoinsulinemic hypoglycemia with hemihypertrophy (HIHGHH)+++H01222///Cowden syndrome","M00676///PI3K-Akt signaling","R02051///phosphatidylethanolamine phosphatidohydrolase Phosphatidylethanolamine + H2O <=> Ethanolamine + Phosphatidate+++R07385///O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate + Ethanolamine+++R01310///phosphatidylcholine phosphatidohydrolase Phosphatidylcholine + H2O <=> Phosphatidate + Choline","GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0032587///ruffle membrane+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0016020///membrane+++GO:0005769///early endosome","GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016301///kinase activity","GO:0032869///cellular response to insulin stimulus+++GO:0045725///positive regulation of glycogen biosynthetic process+++GO:0090630///activation of GTPase activity+++GO:0030334///regulation of cell migration+++GO:0010918///positive regulation of mitochondrial membrane potential+++GO:0006464///cellular protein modification process+++GO:0072659///protein localization to plasma membrane+++GO:0008286///insulin receptor signaling pathway+++GO:0043491///protein kinase B signaling+++GO:0006006///glucose metabolic process+++GO:0007275///multicellular organism development+++GO:0032000///positive regulation of fatty acid beta-oxidation+++GO:0005975///carbohydrate metabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0018105///peptidyl-serine phosphorylation+++GO:0046326///positive regulation of glucose import+++GO:0071156///regulation of cell cycle arrest+++GO:0031340///positive regulation of vesicle fusion+++GO:0045444///fat cell differentiation+++GO:0030335///positive regulation of cell migration+++GO:0060644///mammary gland epithelial cell differentiation+++GO:0010748///negative regulation of plasma membrane long-chain fatty acid transport+++GO:0010907///positive regulation of glucose metabolic process+++GO:0005977///glycogen metabolic process+++GO:0065002///intracellular protein transmembrane transport+++GO:0016310///phosphorylation+++GO:0008643///carbohydrate transport+++GO:0006417///regulation of translation+++GO:0032287///peripheral nervous system myelin maintenance+++GO:0071486///cellular response to high light intensity+++GO:0007165///signal transduction+++GO:0097473///retinal rod cell apoptotic process+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process+++GO:0005978///glycogen biosynthetic process+++GO:2000147///positive regulation of cell motility+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0001934///positive regulation of protein phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0035556///intracellular signal transduction","IPR000961///AGC-kinase, C-terminal+++IPR039027///Serine/threonine-protein kinase RAC alpha/beta+++IPR034677///Protein Kinase B beta, catalytic domain+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011993///PH-like domain superfamily+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR039026///Protein Kinase B, pleckstrin homology domain+++IPR001849///Pleckstrin homology domain+++IPR017892///Protein kinase, C-terminal","[AKT2_HUMAN|Reviewed]RecName: Full=RAC-beta serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=Protein kinase Akt-2; AltName: Full=Protein kinase B beta; Short=PKB beta; AltName: Full=RAC-PK-beta;+++[A0A0A0MRF1_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000351095}; Flags: Fragment;+++[A0A0U4CQG9_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};+++[A0A1B0GXA2_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000407999}; Flags: Fragment;+++[A8MX96_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000375891}; Flags: Fragment;+++[B4DG79_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};+++[C9J258_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000392458}; Flags: Fragment;+++[C9JC83_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000396532}; Flags: Fragment;+++[C9JHS6_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000396968}; Flags: Fragment;+++[C9JIF6_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000403890}; Flags: Fragment;+++[C9JIJ1_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000403842}; Flags: Fragment;+++[E7EVP8_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000404083}; Flags: Fragment;+++[J3KRI8_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000462022}; Flags: Fragment;+++[J3KSY8_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000462715}; Flags: Fragment;+++[J3KT31_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000462776};+++[J3KTC6_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000462919}; Flags: Fragment;+++[J3KTP4_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000463086}; Flags: Fragment;+++[J3QKW1_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000463262}; Flags: Fragment;+++[J3QL45_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000463368}; Flags: Fragment;+++[J3QLS6_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000463686}; Flags: Fragment;+++[M0QZK3_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000470604}; Flags: Fragment;+++[M0QZW8_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000470822}; Flags: Fragment;+++[M0R0P9_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS01060667}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS01060667};+++[M0R275_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000472371}; Flags: Fragment;+++[M0R283_HUMAN|Unreviewed]SubName: Full=RAC-beta serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000472382}; Flags: Fragment;+++[Q6P4H3_HUMAN|Unreviewed]SubName: Full=AKT2 protein {ECO:0000313|EMBL:AAH63421.1};"]
[2113,"'ETS1'",255,289,272,"04014///Ras signaling pathway+++04320///Dorso-ventral axis formation+++05166///HTLV-I infection+++05200///Pathways in cancer+++04218///Cellular senescence+++05211///Renal cell carcinoma+++04013///MAPK signaling pathway - fly",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005737///cytoplasm","GO:0042802///identical protein binding+++GO:0035035///histone acetyltransferase binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding","GO:0006366///transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030335///positive regulation of cell migration+++GO:0034616///response to laminar fluid shear stress+++GO:0030578///PML body organization+++GO:0021854///hypothalamus development+++GO:0010595///positive regulation of endothelial cell migration+++GO:0002376///immune system process+++GO:0044849///estrous cycle+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0046677///response to antibiotic+++GO:0045786///negative regulation of cell cycle+++GO:0009612///response to mechanical stimulus+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:0070555///response to interleukin-1+++GO:0050728///negative regulation of inflammatory response+++GO:0032355///response to estradiol+++GO:0050729///positive regulation of inflammatory response+++GO:0021983///pituitary gland development+++GO:0048870///cell motility+++GO:0070301///cellular response to hydrogen peroxide+++GO:0060055///angiogenesis involved in wound healing+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0007565///female pregnancy+++GO:0009611///response to wounding+++GO:0051272///positive regulation of cellular component movement+++GO:0008285///negative regulation of cell proliferation+++GO:0010628///positive regulation of gene expression+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0001666///response to hypoxia+++GO:0045765///regulation of angiogenesis+++GO:0042981///regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045766///positive regulation of angiogenesis+++GO:0008284///positive regulation of cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006955///immune response","IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR003118///Pointed domain+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR016311///Transforming protein C-ets+++IPR000418///Ets domain","[ETS1_HUMAN|Reviewed]RecName: Full=Protein C-ets-1; AltName: Full=p54;+++[A8K725_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75737, highly similar to Homo sapiens v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), mRNA {ECO:0000313|EMBL:BAF84529.1};+++[B4DW78_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59231, highly similar to C-ets-1 protein {ECO:0000313|EMBL:BAG62940.1};+++[Q6FG54_HUMAN|Unreviewed]SubName: Full=ETS1 protein {ECO:0000313|EMBL:CAG47050.1};+++[V9GYD6_HUMAN|Unreviewed]SubName: Full=Protein C-ets-1 {ECO:0000313|Ensembl:ENSP00000476649}; Flags: Fragment;"]
[2135,"'EXTL2'",174,213,193.5,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin+++01100///Metabolic pathways",null,"M00059///Glycosaminoglycan biosynthesis, heparan sulfate backbone","R05930///UDP-N-acetyl-D-glucosamine + G00157 <=> UDP + G00162","GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0001888///glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0030145///manganese ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0035248///alpha-1,4-N-acetylgalactosaminyltransferase activity+++GO:0047237///glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity+++GO:0046872///metal ion binding+++GO:0005539///glycosaminoglycan binding","GO:0006486///protein glycosylation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0006044///N-acetylglucosamine metabolic process+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0019276///UDP-N-acetylgalactosamine metabolic process","IPR029044///Nucleotide-diphospho-sugar transferases+++IPR015338///Exostosin , C-terminal+++IPR004263///Exostosin-like","[EXTL2_HUMAN|Reviewed]RecName: Full=Exostosin-like 2; EC=2.4.1.223 {ECO:0000250|UniProtKB:Q9ES89}; AltName: Full=Alpha-1,4-N-acetylhexosaminyltransferase EXTL2; AltName: Full=Alpha-GalNAcT EXTL2; AltName: Full=EXT-related protein 2; AltName: Full=Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Contains: RecName: Full=Processed exostosin-like 2;+++[C9IYF5_HUMAN|Unreviewed]SubName: Full=Exostosin-like 2 {ECO:0000313|Ensembl:ENSP00000392255}; Flags: Fragment;+++[C9JEG3_HUMAN|Unreviewed]SubName: Full=Exostosin-like 2 {ECO:0000313|Ensembl:ENSP00000403363}; Flags: Fragment;+++[F5GZK1_HUMAN|Unreviewed]SubName: Full=Exostosin-like 2 {ECO:0000313|Ensembl:ENSP00000444385};+++[O00245_HUMAN|Unreviewed]SubName: Full=EXTL2 {ECO:0000313|EMBL:AAB93669.1}; Flags: Fragment;+++[Q05DH5_HUMAN|Unreviewed]SubName: Full=EXTL2 protein {ECO:0000313|EMBL:AAH14910.1}; Flags: Fragment;+++[Q49A43_HUMAN|Unreviewed]SubName: Full=Exostoses (Multiple)-like 2 {ECO:0000313|EMBL:AAH45681.1};+++[Q8IYF4_HUMAN|Unreviewed]SubName: Full=Exostoses (Multiple)-like 2 {ECO:0000313|EMBL:AAH36015.1};+++[Q8N8F1_HUMAN|Unreviewed]SubName: Full=Exostoses (Multiple)-like 2, isoform CRA_b {ECO:0000313|EMBL:EAW72947.1}; SubName: Full=cDNA FLJ39595 fis, clone SKNSH2001931, highly similar to Exostoses {ECO:0000313|EMBL:BAC04893.1};"]
[2155,"'F7'",6,5,5.5,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0031982///vesicle+++GO:1905286///serine-type peptidase complex+++GO:0005788///endoplasmic reticulum lumen+++GO:0005886///plasma membrane+++GO:0005796///Golgi lumen+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005509///calcium ion binding+++GO:0005102///signaling receptor binding+++GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0008236///serine-type peptidase activity","GO:0006508///proteolysis+++GO:0007599///hemostasis+++GO:0097068///response to thyroxine+++GO:0061476///response to anticoagulant+++GO:0007623///circadian rhythm+++GO:0014070///response to organic cyclic compound+++GO:0002690///positive regulation of leukocyte chemotaxis+++GO:1905225///response to thyrotropin-releasing hormone+++GO:0001666///response to hypoxia+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0007598///blood coagulation, extrinsic pathway+++GO:1905217///response to astaxanthin+++GO:0060416///response to growth hormone+++GO:0032571///response to vitamin K+++GO:0016485///protein processing+++GO:0010037///response to carbon dioxide+++GO:0030335///positive regulation of cell migration+++GO:0043627///response to estrogen+++GO:1904400///response to Thyroid stimulating hormone+++GO:0050927///positive regulation of positive chemotaxis+++GO:0097066///response to thyroid hormone+++GO:0031100///animal organ regeneration+++GO:0033595///response to genistein+++GO:0031667///response to nutrient levels+++GO:0007596///blood coagulation+++GO:0070723///response to cholesterol+++GO:0009725///response to hormone+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0030194///positive regulation of blood coagulation+++GO:0032355///response to estradiol+++GO:1904612///response to 2,3,7,8-tetrachlorodibenzodioxine+++GO:0010641///positive regulation of platelet-derived growth factor receptor signaling pathway","IPR018097///EGF-like calcium-binding, conserved site+++IPR009003///Peptidase S1, PA clan+++IPR001254///Serine proteases, trypsin domain+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR001881///EGF-like calcium-binding domain+++IPR033116///Serine proteases, trypsin family, serine active site+++IPR000294///Gamma-carboxyglutamic acid-rich (GLA) domain+++IPR013032///EGF-like, conserved site+++IPR001314///Peptidase S1A, chymotrypsin family+++IPR017857///Coagulation factor-like, Gla domain superfamily+++IPR033190///Coagulation factor VII+++IPR000742///EGF-like domain+++IPR012224///Peptidase S1A, coagulation factor VII/IX/X/C/Z+++IPR018114///Serine proteases, trypsin family, histidine active site+++IPR035972///Gamma-carboxyglutamic acid-rich (GLA) domain superfamily","[FA7_HUMAN|Reviewed]RecName: Full=Coagulation factor VII; EC=3.4.21.21; AltName: Full=Proconvertin; AltName: Full=Serum prothrombin conversion accelerator; Short=SPCA; AltName: INN=Eptacog alfa; Contains: RecName: Full=Factor VII light chain; Contains: RecName: Full=Factor VII heavy chain; Flags: Precursor;+++[A3RMR0_HUMAN|Unreviewed]SubName: Full=Coagulation factor VII {ECO:0000313|EMBL:ABO20833.1}; Flags: Fragment;+++[A3RMR1_HUMAN|Unreviewed]SubName: Full=Coagulation factor VII {ECO:0000313|EMBL:ABO20834.1}; Flags: Fragment;+++[B4DPM2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55738, highly similar to Coagulation factor VII {ECO:0000313|EMBL:BAG60634.1};+++[E9PH36_HUMAN|Unreviewed]SubName: Full=Coagulation factor VII {ECO:0000313|Ensembl:ENSP00000387669};+++[F5H8B0_HUMAN|Unreviewed]SubName: Full=Coagulation factor VII {ECO:0000313|Ensembl:ENSP00000442051};+++[L8EC53_HUMAN|Unreviewed]SubName: Full=Alternative protein F7 {ECO:0000313|EMBL:CCQ42967.1};"]
[218,"'ALDH3A1'",32,11,21.5,"05204///Chemical carcinogenesis+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis+++00340///Histidine metabolism+++00410///beta-Alanine metabolism+++01120///Microbial metabolism in diverse environments+++00980///Metabolism of xenobiotics by cytochrome P450+++00350///Tyrosine metabolism+++01100///Metabolic pathways+++00360///Phenylalanine metabolism+++00982///Drug metabolism - cytochrome P450","H01027///Anophthalmia and microphthalmia (A/M)",null,"R04883///3,4-Dihydroxymandelaldehyde:NADP+ oxidoreductase   3,4-Dihydroxymandelaldehyde + NADP+ + H2O <=> 3,4-Dihydroxymandelate + NADPH + H++++R04888///3-Methoxy-4-hydroxyphenylacetaldehyde:NAD+ oxidoreductase   3-Methoxy-4-hydroxyphenylacetaldehyde + NAD+ + H2O <=> Homovanillate + NADH + H++++R08307///3-carbamoyl-2-phenylpropionaldehyde:NAD+ oxidoreductase   3-Carbamoyl-2-phenylpropionaldehyde + NAD+ + H2O <=> 3-Carbamoyl-2-phenylpropionic acid + NADH + H++++R04882///3,4-Dihydroxymandelaldehyde:NAD+ oxidoreductase   3,4-Dihydroxymandelaldehyde + NAD+ + H2O <=> 3,4-Dihydroxymandelate + NADH + H++++R04996///3-Methylimidazole acetaldehyde:NAD+ oxidoreductase   Methylimidazole acetaldehyde + NAD+ + H2O <=> Methylimidazoleacetic acid + NADH + H++++R03302///3,4-Dihydroxyphenylacetaldehyde:NADP+ oxidoreductase   3,4-Dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H++++R08283///carboxyphosphamide:NADP+ oxidoreductase   Aldophosphamide + NADP+ + H2O <=> Carboxyphosphamide + NADPH + H++++R02536///Phenylacetaldehyde:NAD+ oxidoreductase   Phenylacetaldehyde + NAD+ + H2O <=> Phenylacetic acid + NADH + H++++R04892///3-Methoxy-4-hydroxyphenylglycolaldehyde:NADP+ oxidoreductase   3-Methoxy-4-hydroxyphenylglycolaldehyde + NADP+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADPH + H++++R00711///Acetaldehyde:NADP+ oxidoreductase   Acetaldehyde + NADP+ + H2O <=> Acetate + NADPH + H++++R07104///Chloral:NAD(P)+ oxidoreductase   Chloral hydrate + NAD+ <=> Trichloroacetate + NADH + H++++R04891///3-Methoxy-4-hydroxyphenylglycolaldehyde:NAD+ oxidoreductase   3-Methoxy-4-hydroxyphenylglycolaldehyde + NAD+ + H2O <=> 3-Methoxy-4-hydroxymandelate + NADH + H++++R08282///carboxyphosphamide:NAD+ oxidoreductase   Aldophosphamide + NAD+ + H2O <=> Carboxyphosphamide + NADH + H++++R02537///Aldehyde:NADP+ oxidoreductase   Phenylacetaldehyde + NADP+ + H2O <=> Phenylacetic acid + NADPH + H++++R04889///3-Methoxy-4-hydroxyphenylacetaldehyde:NADP+ oxidoreductase   3-Methoxy-4-hydroxyphenylacetaldehyde + NADP+ + H2O <=> Homovanillate + NADPH + H++++R02695///4-Hydroxyphenylacetaldehyde:NAD+ oxidoreductase   4-Hydroxyphenylacetaldehyde + NAD+ + H2O <=> 4-Hydroxyphenylacetate + NADH + H++++R03300///3,4-Dihydroxyphenylacetaldehyde:NAD+ oxidoreductase   3,4-Dihydroxyphenylacetaldehyde + NAD+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADH + H++++R00904///3-aminopropanal:NAD+ oxidoreductase   3-Aminopropanal + NAD+ + H2O <=> beta-Alanine + NADH + H++++R02697///4-Hydroxyphenylacetaldehyde:NADP+ oxidoreductase   4-Hydroxyphenylacetaldehyde + NADP+ + H2O <=> 4-Hydroxyphenylacetate + NADPH + H+","GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane","GO:0016620///oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor+++GO:0004029///aldehyde dehydrogenase (NAD) activity+++GO:0018479///benzaldehyde dehydrogenase (NAD+) activity+++GO:0008106///alcohol dehydrogenase (NADP+) activity+++GO:0005515///protein binding+++GO:0004028///3-chloroallyl aldehyde dehydrogenase activity+++GO:0004030///aldehyde dehydrogenase [NAD(P)+] activity+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0006805///xenobiotic metabolic process+++GO:0006081///cellular aldehyde metabolic process","IPR029510///Aldehyde dehydrogenase, glutamic acid active site+++IPR016163///Aldehyde dehydrogenase, C-terminal+++IPR016162///Aldehyde dehydrogenase, N-terminal+++IPR016160///Aldehyde dehydrogenase, cysteine active site+++IPR016161///Aldehyde/histidinol dehydrogenase+++IPR012394///Aldehyde dehydrogenase NAD(P)-dependent+++IPR015590///Aldehyde dehydrogenase domain","[AL3A1_HUMAN|Reviewed]RecName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring; EC=1.2.1.5 {ECO:0000269|PubMed:1737758, ECO:0000269|PubMed:22021038}; AltName: Full=ALDHIII; AltName: Full=Aldehyde dehydrogenase 3; AltName: Full=Aldehyde dehydrogenase family 3 member A1;+++[A8MYB8_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000378923};+++[C9JKT2_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000388369}; Flags: Fragment;+++[C9JMC5_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000389766}; Flags: Fragment;+++[E9PNN6_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000434685};+++[I3L1H6_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000458841}; Flags: Fragment;+++[I3L3I9_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000460482};+++[I3L3W9_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000460792}; Flags: Fragment;+++[I3L4E5_HUMAN|Unreviewed]SubName: Full=Aldehyde dehydrogenase, dimeric NADP-preferring {ECO:0000313|Ensembl:ENSP00000461189}; Flags: Fragment;+++[Q6PKA6_HUMAN|Unreviewed]SubName: Full=ALDH3A1 protein {ECO:0000313|EMBL:AAH04102.1}; Flags: Fragment;"]
[219293,"'ATAD3C'",12.49,1.05,6.77,{"$nulls":4},"GO:0005739///mitochondrion","GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0000166///nucleotide binding","GO:0007005///mitochondrion organization","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR021911///ATPase family AAA domain-containing protein 3, domain of unknown function DUF3523+++IPR003593///AAA+ ATPase domain+++IPR039188///ATPase family AAA domain-containing protein 3+++IPR003959///ATPase, AAA-type, core","[ATD3C_HUMAN|Reviewed]RecName: Full=ATPase family AAA domain-containing protein 3C;+++[J3QSF3_HUMAN|Unreviewed]SubName: Full=ATPase family AAA domain-containing protein 3C {ECO:0000313|Ensembl:ENSP00000464661}; Flags: Fragment;"]
[2193,"'FARSA'",1807,1219,1513,"00970///Aminoacyl-tRNA biosynthesis","H00891///Combined oxidative phosphorylation deficiency (COXPD)+++H00266///Hereditary spastic paraplegia (SPG)","M00360///Aminoacyl-tRNA biosynthesis, prokaryotes+++M00359///Aminoacyl-tRNA biosynthesis, eukaryotes","R03660///L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)   ATP + L-Phenylalanine + tRNA(Phe) <=> AMP + Diphosphate + L-Phenylalanyl-tRNA(Phe)","GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0009328///phenylalanine-tRNA ligase complex+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0004812///aminoacyl-tRNA ligase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004826///phenylalanine-tRNA ligase activity+++GO:0000049///tRNA binding+++GO:0016874///ligase activity","GO:0006432///phenylalanyl-tRNA aminoacylation+++GO:0043039///tRNA aminoacylation+++GO:0006412///translation+++GO:0051290///protein heterotetramerization","IPR036390///Winged helix DNA-binding domain superfamily+++IPR006195///Aminoacyl-tRNA synthetase, class II+++IPR002319///Phenylalanyl-tRNA synthetase+++IPR004529///Phenylalanyl-tRNA synthetase, class IIc, alpha subunit","[SYFA_HUMAN|Reviewed]RecName: Full=Phenylalanine--tRNA ligase alpha subunit; EC=6.1.1.20 {ECO:0000269|PubMed:20223217}; AltName: Full=CML33; AltName: Full=Phenylalanyl-tRNA synthetase alpha subunit; Short=PheRS;+++[K7EK06_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000465402}; Flags: Fragment;+++[K7EPH2_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000467384}; Flags: Fragment;+++[K7ER00_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000468051};+++[K7ER16_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000468068};+++[K7ERS0_HUMAN|Unreviewed]SubName: Full=Phenylalanine--tRNA ligase alpha subunit {ECO:0000313|Ensembl:ENSP00000468384}; Flags: Fragment;+++[Q6IBR2_HUMAN|Unreviewed]SubName: Full=FARSLA protein {ECO:0000313|EMBL:CAG33021.1}; SubName: Full=Phenylalanine-tRNA synthetase-like, alpha subunit, isoform CRA_b {ECO:0000313|EMBL:EAW84329.1}; SubName: Full=cDNA FLJ34774 fis, clone NT2NE2003309, highly similar to Phenylalanyl-tRNA synthetase alpha chain {ECO:0000313|EMBL:BAG52481.1};"]
[219699,"'UNC5B'",109,163,136,"04360///Axon guidance",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0045121///membrane raft","GO:0005515///protein binding+++GO:0005042///netrin receptor activity","GO:0043524///negative regulation of neuron apoptotic process+++GO:0038007///netrin-activated signaling pathway+++GO:0006915///apoptotic process+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:0007165///signal transduction+++GO:0007275///multicellular organism development+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0033564///anterior/posterior axon guidance+++GO:0001525///angiogenesis","IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR003598///Immunoglobulin subtype 2+++IPR037936///Netrin receptor UNC5+++IPR036179///Immunoglobulin-like domain superfamily+++IPR011029///Death-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR033772///UPA domain+++IPR003599///Immunoglobulin subtype+++IPR000884///Thrombospondin type-1 (TSP1) repeat+++IPR007110///Immunoglobulin-like domain+++IPR000906///ZU5 domain+++IPR000488///Death domain+++IPR013098///Immunoglobulin I-set","[UNC5B_HUMAN|Reviewed]RecName: Full=Netrin receptor UNC5B; AltName: Full=Protein unc-5 homolog 2; AltName: Full=Protein unc-5 homolog B; AltName: Full=p53-regulated receptor for death and life protein 1 {ECO:0000303|PubMed:12598906}; Short=p53RDL1 {ECO:0000303|PubMed:12598906}; Flags: Precursor;"]
[219902,"'TMEM136'",165.05,147,156.025,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR006634///TRAM/LAG1/CLN8 homology domain","[TM136_HUMAN|Reviewed]RecName: Full=Transmembrane protein 136;+++[A8K0W5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78133 {ECO:0000313|EMBL:BAF82369.1};"]
[220108,"'FAM124A'",629,743.01,686.005,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"IPR029380///FAM124","[F124A_HUMAN|Reviewed]RecName: Full=Protein FAM124A;"]
[2207,"'FCER1G'",6,4,5,"05310///Asthma+++04625///C-type lectin receptor signaling pathway+++04611///Platelet activation+++05152///Tuberculosis+++04664///Fc epsilon RI signaling pathway+++04072///Phospholipase D signaling pathway+++04071///Sphingolipid signaling pathway+++04650///Natural killer cell mediated cytotoxicity",{"$nulls":3},"GO:0009986///cell surface+++GO:0009897///external side of plasma membrane+++GO:0101003///ficolin-1-rich granule membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070821///tertiary granule membrane+++GO:0032998///Fc-epsilon receptor I complex","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0019864///IgG binding+++GO:0019863///IgE binding+++GO:0019767///IgE receptor activity","GO:0038156///interleukin-3-mediated signaling pathway+++GO:0043312///neutrophil degranulation+++GO:0032755///positive regulation of interleukin-6 production+++GO:0050776///regulation of immune response+++GO:0030593///neutrophil chemotaxis+++GO:0007229///integrin-mediated signaling pathway+++GO:0007165///signal transduction+++GO:0010543///regulation of platelet activation+++GO:0042742///defense response to bacterium+++GO:0002376///immune system process+++GO:0051260///protein homooligomerization+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0030316///osteoclast differentiation+++GO:0006911///phagocytosis, engulfment+++GO:0032765///positive regulation of mast cell cytokine production+++GO:0050900///leukocyte migration+++GO:0007596///blood coagulation+++GO:0002431///Fc receptor mediated stimulatory signaling pathway+++GO:0042590///antigen processing and presentation of exogenous peptide antigen via MHC class I+++GO:0031623///receptor internalization+++GO:0032753///positive regulation of interleukin-4 production+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0072659///protein localization to plasma membrane+++GO:0050778///positive regulation of immune response+++GO:0002554///serotonin secretion by platelet+++GO:0016064///immunoglobulin mediated immune response+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0032623///interleukin-2 production+++GO:0033026///negative regulation of mast cell apoptotic process+++GO:0045087///innate immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0002292///T cell differentiation involved in immune response+++GO:0038094///Fc-gamma receptor signaling pathway+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0032733///positive regulation of interleukin-10 production+++GO:0001805///positive regulation of type III hypersensitivity+++GO:0043306///positive regulation of mast cell degranulation+++GO:0001812///positive regulation of type I hypersensitivity+++GO:0002283///neutrophil activation involved in immune response+++GO:0030168///platelet activation+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0050766///positive regulation of phagocytosis+++GO:0045576///mast cell activation+++GO:0001798///positive regulation of type IIa hypersensitivity","IPR003110///Phosphorylated immunoreceptor signalling ITAM+++IPR021663///T-cell surface glycoprotein CD3 zeta subunit/High affinity IgE receptor gamma subunit","[FCERG_HUMAN|Reviewed]RecName: Full=High affinity immunoglobulin epsilon receptor subunit gamma; AltName: Full=Fc receptor gamma-chain; Short=FcRgamma; AltName: Full=Fc-epsilon RI-gamma; AltName: Full=IgE Fc receptor subunit gamma; Short=FceRI gamma; Flags: Precursor;+++[A6NCQ8_HUMAN|Unreviewed]SubName: Full=High affinity immunoglobulin epsilon receptor subunit gamma {ECO:0000313|Ensembl:ENSP00000356971};"]
[221074,"'SLC39A12'",2,2,2,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:1903561///extracellular vesicle+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0046873///metal ion transmembrane transporter activity+++GO:0005385///zinc ion transmembrane transporter activity","GO:0006882///cellular zinc ion homeostasis+++GO:0006829///zinc ion transport+++GO:0055085///transmembrane transport+++GO:0010975///regulation of neuron projection development+++GO:0007165///signal transduction+++GO:0006811///ion transport+++GO:0071578///zinc ion import across plasma membrane+++GO:0030001///metal ion transport+++GO:0031113///regulation of microtubule polymerization","IPR003689///Zinc/iron permease","[S39AC_HUMAN|Reviewed]RecName: Full=Zinc transporter ZIP12; AltName: Full=LIV-1 subfamily of ZIP zinc transporter 8; Short=LZT-Hs8; AltName: Full=Solute carrier family 39 member 12; AltName: Full=Zrt- and Irt-like protein 12; Short=ZIP-12;"]
[221322,"'TBC1D32'",18,30,24,{"$nulls":4},"GO:0042995///cell projection+++GO:0005929///cilium+++GO:0005737///cytoplasm","GO:0004519///endonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0043010///camera-type eye development+++GO:0007275///multicellular organism development+++GO:0021915///neural tube development+++GO:0042733///embryonic digit morphogenesis+++GO:0007224///smoothened signaling pathway+++GO:0007368///determination of left/right symmetry+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0060041///retina development in camera-type eye+++GO:0003406///retinal pigment epithelium development+++GO:0002088///lens development in camera-type eye+++GO:1905515///non-motile cilium assembly+++GO:0061512///protein localization to cilium+++GO:0007507///heart development","IPR032735///Protein broad-minded+++IPR039156///UPF0183/Protein broad-minded+++IPR035969///Rab-GTPase-TBC domain superfamily","[BROMI_HUMAN|Reviewed]RecName: Full=Protein broad-minded; AltName: Full=TBC1 domain family member 32;+++[A2A304_HUMAN|Unreviewed]SubName: Full=Protein broad-minded {ECO:0000313|Ensembl:ENSP00000397993}; Flags: Fragment;+++[H0YBP0_HUMAN|Unreviewed]SubName: Full=Protein broad-minded {ECO:0000313|Ensembl:ENSP00000429928}; Flags: Fragment;"]
[221504,"'ZBTB9'",211,174,192.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR011333///SKP1/BTB/POZ domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR000210///BTB/POZ domain","[ZBTB9_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 9;+++[A0A087WTT7_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000478118}; Flags: Fragment;+++[A0A087X1K1_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000484265}; Flags: Fragment;+++[A0A087X1Z5_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 9 {ECO:0000313|Ensembl:ENSP00000484571}; Flags: Fragment;+++[A0A1U9X8U5_HUMAN|Unreviewed]SubName: Full=ZBTB9 {ECO:0000313|EMBL:AQY77222.1};"]
[221833,"'SP8'",8,7,7.5,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0016811///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0047708///biotinidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006807///nitrogen compound metabolic process+++GO:0009953///dorsal/ventral pattern formation+++GO:0009954///proximal/distal pattern formation+++GO:0007417///central nervous system development+++GO:0030326///embryonic limb morphogenesis+++GO:0006768///biotin metabolic process","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[SP8_HUMAN|Reviewed]RecName: Full=Transcription factor Sp8; AltName: Full=Specificity protein 8;+++[A0A087X0Q6_HUMAN|Unreviewed]SubName: Full=Sp8 transcription factor, isoform CRA_d {ECO:0000313|EMBL:EAW93732.1}; SubName: Full=Transcription factor Sp8 {ECO:0000313|Ensembl:ENSP00000483588};+++[A0A2R8Y5J9_HUMAN|Unreviewed]SubName: Full=Biotinidase, isoform CRA_c {ECO:0000313|EMBL:EAW64256.1};+++[A8K350_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75141, highly similar to Homo sapiens Sp8 transcription factor (SP8), mRNA {ECO:0000313|EMBL:BAF83154.1};+++[C9J387_HUMAN|Unreviewed]SubName: Full=Biotinidase {ECO:0000313|Ensembl:ENSP00000397113}; Flags: Fragment;+++[C9JSN9_HUMAN|Unreviewed]SubName: Full=Biotinidase {ECO:0000313|Ensembl:ENSP00000394277}; Flags: Fragment;+++[L0R6D3_HUMAN|Unreviewed]SubName: Full=Alternative protein BTD {ECO:0000313|EMBL:CCO13687.1};+++[Q4G0T0_HUMAN|Unreviewed]SubName: Full=SP8 protein {ECO:0000313|EMBL:AAH38669.1};"]
[222194,"'RSBN1L'",129,130,129.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus",null,null,"IPR026306///RSBN1/Dpy-21","[RSBNL_HUMAN|Reviewed]RecName: Full=Round spermatid basic protein 1-like protein;+++[C9JM20_HUMAN|Unreviewed]SubName: Full=Round spermatid basic protein 1-like protein {ECO:0000313|Ensembl:ENSP00000414313}; Flags: Fragment;+++[H7C2D3_HUMAN|Unreviewed]SubName: Full=Round spermatid basic protein 1-like protein {ECO:0000313|Ensembl:ENSP00000405231}; Flags: Fragment;"]
[222584,"'FAM83B'",18,18,18,{"$nulls":4},"GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0004630///phospholipase D activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0036313///phosphatidylinositol 3-kinase catalytic subunit binding+++GO:0019901///protein kinase binding","GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0008283///cell proliferation","IPR012461///FAM83","[FA83B_HUMAN|Reviewed]RecName: Full=Protein FAM83B {ECO:0000305};"]
[223117,"'SEMA3D'",16,18,17,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0038191///neuropilin binding+++GO:0030215///semaphorin receptor binding+++GO:0045499///chemorepellent activity","GO:0030335///positive regulation of cell migration+++GO:0030154///cell differentiation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0050919///negative chemotaxis+++GO:0001755///neural crest cell migration+++GO:0007399///nervous system development+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0007275///multicellular organism development","IPR003599///Immunoglobulin subtype+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR027231///Semaphorin+++IPR001627///Sema domain+++IPR007110///Immunoglobulin-like domain+++IPR013783///Immunoglobulin-like fold+++IPR036352///Sema domain superfamily+++IPR016201///PSI domain+++IPR036179///Immunoglobulin-like domain superfamily","[SEM3D_HUMAN|Reviewed]RecName: Full=Semaphorin-3D; Flags: Precursor;+++[C9JYT6_HUMAN|Unreviewed]SubName: Full=Semaphorin-3D {ECO:0000313|Ensembl:ENSP00000401366};"]
[2256,"'FGF11'",1461,1836,1648.5,null,"H00606///Early infantile epileptic encephalopathy+++H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0005576///extracellular region","GO:0008083///growth factor activity","GO:0007267///cell-cell signaling+++GO:0007165///signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0007399///nervous system development","IPR002209///Fibroblast growth factor family+++IPR008996///Cytokine IL1/FGF+++IPR028253///Fibroblast growth factor 11","[FGF11_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor 11; Short=FGF-11; AltName: Full=Fibroblast growth factor homologous factor 3; Short=FHF-3;+++[B7Z1C3_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442};+++[I3L4N4_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442};+++[Q6LA99_HUMAN|Unreviewed]RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442}; Short=FGF {ECO:0000256|RuleBase:RU049442}; Flags: Fragment;"]
[2275,"'FHL3'",1227,1277,1252,{"$nulls":4},"GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0030018///Z disc+++GO:0001725///stress fiber","GO:0046872///metal ion binding+++GO:0003779///actin binding","GO:0030036///actin cytoskeleton organization+++GO:0007517///muscle organ development","IPR037987///Four and a half LIM domains protein 2/3/5+++IPR001781///Zinc finger, LIM-type","[FHL3_HUMAN|Reviewed]RecName: Full=Four and a half LIM domains protein 3; Short=FHL-3; AltName: Full=Skeletal muscle LIM-protein 2; Short=SLIM-2;+++[Q96C98_HUMAN|Unreviewed]SubName: Full=FHL3 protein {ECO:0000313|EMBL:AAH14501.1};"]
[2281,"'FKBP1B'",99,69,84,{"$nulls":4},"GO:0034704///calcium channel complex+++GO:0005829///cytosol+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005737///cytoplasm+++GO:0016529///sarcoplasmic reticulum+++GO:0030018///Z disc+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0019855///calcium channel inhibitor activity+++GO:0005528///FK506 binding+++GO:0016853///isomerase activity+++GO:0005102///signaling receptor binding+++GO:0044325///ion channel binding+++GO:0005515///protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0030551///cyclic nucleotide binding+++GO:0005219///ryanodine-sensitive calcium-release channel activity","GO:0006458///'de novo' protein folding+++GO:0019227///neuronal action potential propagation+++GO:1903779///regulation of cardiac conduction+++GO:0051209///release of sequestered calcium ion into cytosol+++GO:0002027///regulation of heart rate+++GO:0051280///negative regulation of release of sequestered calcium ion into cytosol+++GO:0061077///chaperone-mediated protein folding+++GO:0051284///positive regulation of sequestering of calcium ion+++GO:0014808///release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0042026///protein refolding+++GO:0034220///ion transmembrane transport+++GO:0000413///protein peptidyl-prolyl isomerization+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0051775///response to redox state+++GO:0006939///smooth muscle contraction+++GO:0033197///response to vitamin E+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0009749///response to glucose+++GO:0048680///positive regulation of axon regeneration+++GO:0022417///protein maturation by protein folding+++GO:0035584///calcium-mediated signaling using intracellular calcium source+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0042542///response to hydrogen peroxide+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0042098///T cell proliferation+++GO:0010033///response to organic substance+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0030073///insulin secretion+++GO:0010459///negative regulation of heart rate","IPR001179///FKBP-type peptidyl-prolyl cis-trans isomerase domain+++IPR023566///Peptidyl-prolyl cis-trans isomerase, FKBP-type","[FKB1B_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1B; Short=PPIase FKBP1B; EC=5.2.1.8; AltName: Full=12.6 kDa FK506-binding protein; Short=12.6 kDa FKBP; Short=FKBP-12.6; AltName: Full=FK506-binding protein 1B; Short=FKBP-1B; AltName: Full=Immunophilin FKBP12.6; AltName: Full=Rotamase; AltName: Full=h-FKBP-12;+++[F8W6G9_HUMAN|Unreviewed]RecName: Full=Peptidylprolyl isomerase {ECO:0000256|PROSITE-ProRule:PRU00277}; EC=5.2.1.8 {ECO:0000256|PROSITE-ProRule:PRU00277};+++[G5E9U6_HUMAN|Unreviewed]SubName: Full=FK506 binding protein 1B, 12.6 kDa, isoform CRA_c {ECO:0000313|EMBL:EAX00770.1}; SubName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1B {ECO:0000313|Ensembl:ENSP00000416349};+++[H7C0Y3_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase FKBP1B {ECO:0000313|Ensembl:ENSP00000397444}; Flags: Fragment;"]
[22837,"'COBLL1'",274,540,407,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome","GO:0003779///actin binding+++GO:0045296///cadherin binding+++GO:0003785///actin monomer binding","GO:0051639///actin filament network formation+++GO:0030041///actin filament polymerization","IPR019025///Cordon-bleu, ubiquitin-like domain+++IPR039895///Protein cordon-bleu-like+++IPR003124///WH2 domain","[COBL1_HUMAN|Reviewed]RecName: Full=Cordon-bleu protein-like 1;+++[A0A0B4J1Z0_HUMAN|Unreviewed]SubName: Full=COBL-like 1, isoform CRA_a {ECO:0000313|EMBL:EAX11338.1}; SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000416311};+++[A0A0D9SG04_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000487041};+++[A0A0X1KG75_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000387326}; Flags: Fragment;+++[B7Z2P5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56478, highly similar to Homo sapiens COBL-like 1 (COBLL1), mRNA {ECO:0000313|EMBL:BAH11931.1};+++[C9J5Y6_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000397835}; Flags: Fragment;+++[C9J8C4_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000397520}; Flags: Fragment;+++[C9JAU3_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000406062}; Flags: Fragment;+++[C9JK90_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000409237}; Flags: Fragment;+++[C9JWZ0_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000387967}; Flags: Fragment;+++[F8WEK0_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000388110}; Flags: Fragment;+++[H7C1G2_HUMAN|Unreviewed]SubName: Full=Cordon-bleu protein-like 1 {ECO:0000313|Ensembl:ENSP00000400146}; Flags: Fragment;"]
[22858,"'ICK'",152,197,174.5,null,"H00972///Endocrine-cerebro-osteodysplasia syndrome",null,null,"GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005929///cilium+++GO:0036064///ciliary basal body+++GO:0001650///fibrillar center+++GO:0005829///cytosol+++GO:0097542///ciliary tip+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0097546///ciliary base","GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0000287///magnesium ion binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0035721///intraciliary retrograde transport+++GO:0030030///cell projection organization+++GO:0016310///phosphorylation+++GO:0007165///signal transduction+++GO:0042073///intraciliary transport+++GO:0006468///protein phosphorylation+++GO:0060271///cilium assembly+++GO:0035720///intraciliary anterograde transport+++GO:0010468///regulation of gene expression+++GO:0035556///intracellular signal transduction","IPR008271///Serine/threonine-protein kinase, active site+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily","[ICK_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase ICK; EC=2.7.11.1 {ECO:0000269|PubMed:10699974}; AltName: Full=Intestinal cell kinase; Short=hICK; AltName: Full=Laryngeal cancer kinase 2; Short=LCK2; AltName: Full=MAK-related kinase; Short=MRK;+++[A0A024RD59_HUMAN|Unreviewed]SubName: Full=Intestinal cell (MAK-like) kinase, isoform CRA_a {ECO:0000313|EMBL:EAX04404.1};+++[B3KQG4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90411 fis, clone NT2RP3000022, highly similar to Serine/threonine-protein kinase ICK {ECO:0000313|EMBL:BAG52026.1};"]
[22874,"'PLEKHA6'",103,103,103,"00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04137///Mitophagy - animal+++04140///Autophagy - animal+++01100///Metabolic pathways",null,null,"R05795///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate+++R03362///ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate","GO:0030139///endocytic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005942///phosphatidylinositol 3-kinase complex","GO:0001727///lipid kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0035091///phosphatidylinositol binding+++GO:0042803///protein homodimerization activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity+++GO:0005524///ATP binding","GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0016477///cell migration+++GO:0043491///protein kinase B signaling+++GO:0009267///cellular response to starvation+++GO:1905037///autophagosome organization","IPR001849///Pleckstrin homology domain+++IPR011993///PH-like domain superfamily","[PKHA6_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family A member 6; Short=PH domain-containing family A member 6; AltName: Full=Phosphoinositol 3-phosphate-binding protein 3; Short=PEPP-3;+++[A0A1B0GUN5_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 6 {ECO:0000313|Ensembl:ENSP00000490182};+++[A0A1B0GW03_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 6 {ECO:0000313|Ensembl:ENSP00000490720}; Flags: Fragment;+++[A5XEJ2_HUMAN|Unreviewed]SubName: Full=Phosphoinositol 3-phosphate-binding protein 3 {ECO:0000313|EMBL:ABL59912.1}; Flags: Fragment;+++[A5XEJ3_HUMAN|Unreviewed]SubName: Full=Phosphoinositol 3-phosphate-binding protein 3 {ECO:0000313|EMBL:ABL59913.1}; Flags: Fragment;+++[A5XEJ4_HUMAN|Unreviewed]SubName: Full=Phosphoinositol 3-phosphate-binding protein 3 {ECO:0000313|EMBL:ABL59914.1}; Flags: Fragment;+++[A5XEJ5_HUMAN|Unreviewed]SubName: Full=Phosphoinositol 3-phosphate-binding protein 3 {ECO:0000313|EMBL:ABL59915.1}; Flags: Fragment;+++[A5XEJ6_HUMAN|Unreviewed]SubName: Full=Phosphoinositol 3-phosphate-binding protein 3 {ECO:0000313|EMBL:ABL59916.1}; Flags: Fragment;+++[A5XEJ7_HUMAN|Unreviewed]SubName: Full=Phosphoinositol 3-phosphate-binding protein 3 {ECO:0000313|EMBL:ABL59917.1}; Flags: Fragment;+++[A5XEJ8_HUMAN|Unreviewed]SubName: Full=Truncated phosphoinositol 3-phosphate-binding protein 3 {ECO:0000313|EMBL:ABL59918.1}; Flags: Fragment;+++[Q5VTI5_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 6 {ECO:0000313|Ensembl:ENSP00000402046};+++[Q96FR0_HUMAN|Unreviewed]SubName: Full=PLEKHA6 protein {ECO:0000313|EMBL:AAH10522.1};"]
[22889,"'KHDC4'",523,617,570,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005681///spliceosomal complex+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0006376///mRNA splice site selection+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing","IPR031121///KH domain containing protein RIK/BLOM7+++IPR036612///K Homology domain, type 1 superfamily","[KHDC4_HUMAN|Reviewed]RecName: Full=KH homology domain-containing protein 4 {ECO:0000312|HGNC:HGNC:29145}; AltName: Full=Brings lots of money 7 {ECO:0000303|PubMed:19641227}; AltName: Full=Pre-mRNA splicing factor protein KHDC4 {ECO:0000305};+++[A0A0S2Z5A4_HUMAN|Unreviewed]SubName: Full=KIAA0907 isoform 2 {ECO:0000313|EMBL:ALQ34014.1};+++[A0A0S2Z5B9_HUMAN|Unreviewed]SubName: Full=KIAA0907 isoform 1 {ECO:0000313|EMBL:ALQ34013.1}; SubName: Full=KIAA0907, isoform CRA_b {ECO:0000313|EMBL:EAW53023.1}; Flags: Fragment;+++[D3DVA4_HUMAN|Unreviewed]SubName: Full=KIAA0907, isoform CRA_a {ECO:0000313|EMBL:EAW53022.1};"]
[22906,"'TRAK1'",1450,1556,1503,{"$nulls":4},"GO:0005769///early endosome+++GO:0044295///axonal growth cone+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:1904115///axon cytoplasm+++GO:0005768///endosome+++GO:0030425///dendrite+++GO:0005634///nucleus+++GO:0005938///cell cortex+++GO:0048471///perinuclear region of cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0032839///dendrite cytoplasm+++GO:0005737///cytoplasm+++GO:0031966///mitochondrial membrane","GO:0030911///TPR domain binding+++GO:0050811///GABA receptor binding+++GO:0017022///myosin binding+++GO:0005102///signaling receptor binding+++GO:0005515///protein binding","GO:0008333///endosome to lysosome transport+++GO:0098957///anterograde axonal transport of mitochondrion+++GO:0008104///protein localization+++GO:0048813///dendrite morphogenesis+++GO:0047496///vesicle transport along microtubule+++GO:0019896///axonal transport of mitochondrion+++GO:0050772///positive regulation of axonogenesis+++GO:0048311///mitochondrion distribution+++GO:0008089///anterograde axonal transport+++GO:0022008///neurogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006605///protein targeting+++GO:0006493///protein O-linked glycosylation","IPR022154///Trafficking kinesin-binding protein domain+++IPR006933///HAP1, N-terminal","[TRAK1_HUMAN|Reviewed]RecName: Full=Trafficking kinesin-binding protein 1; AltName: Full=106 kDa O-GlcNAc transferase-interacting protein; AltName: Full=Protein Milton {ECO:0000303|PubMed:24995978};+++[A0A024R2M0_HUMAN|Unreviewed]SubName: Full=Trafficking protein, kinesin binding 1, isoform CRA_d {ECO:0000313|EMBL:EAW64642.1};+++[A0A087X0N0_HUMAN|Unreviewed]SubName: Full=Trafficking kinesin-binding protein 1 {ECO:0000313|Ensembl:ENSP00000483516};+++[A0A0D9SFL5_HUMAN|Unreviewed]SubName: Full=Trafficking kinesin-binding protein 1 {ECO:0000313|Ensembl:ENSP00000486713};+++[A0A0D9SGH2_HUMAN|Unreviewed]SubName: Full=Trafficking kinesin-binding protein 1 {ECO:0000313|Ensembl:ENSP00000487488};+++[B7Z218_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60104, highly similar to Homo sapiens OGT(O-Glc-NAc transferase)-interacting protein 106 kDa (OIP106), mRNA {ECO:0000313|EMBL:BAH11704.1};+++[B7ZAE5_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79159, highly similar to Trafficking kinesin-binding protein 1 {ECO:0000313|EMBL:BAH14631.1};+++[C9JC32_HUMAN|Unreviewed]SubName: Full=Trafficking kinesin-binding protein 1 {ECO:0000313|Ensembl:ENSP00000379478}; SubName: Full=Trafficking protein, kinesin binding 1, isoform CRA_c {ECO:0000313|EMBL:EAW64640.1};+++[F8WDH2_HUMAN|Unreviewed]SubName: Full=Trafficking kinesin-binding protein 1 {ECO:0000313|Ensembl:ENSP00000409940};+++[H7C3T3_HUMAN|Unreviewed]SubName: Full=Trafficking kinesin-binding protein 1 {ECO:0000313|Ensembl:ENSP00000413729}; Flags: Fragment;"]
[22928,"'SEPHS2'",491,422,456.5,"00450///Selenocompound metabolism+++01100///Metabolic pathways",null,null,"R03595///ATP:selenide, water phosphotransferase   ATP + Hydrogen selenide + H2O <=> AMP + Selenophosphoric acid + Orthophosphate","GO:0005829///cytosol+++GO:0005575///cellular_component+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0004756///selenide, water dikinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity","GO:0070329///tRNA seleno-modification+++GO:0001887///selenium compound metabolic process+++GO:0016260///selenocysteine biosynthetic process+++GO:0016310///phosphorylation+++GO:0016259///selenocysteine metabolic process","IPR004536///Selenophosphate synthetase+++IPR023061///Selenophosphate synthetase, class I+++IPR010918///PurM-like, C-terminal domain+++IPR036921///PurM-like, N-terminal domain superfamily+++IPR036676///PurM-like, C-terminal domain superfamily+++IPR016188///PurM-like, N-terminal domain","[SPS2_HUMAN|Reviewed]RecName: Full=Selenide, water dikinase 2; EC=2.7.9.3; AltName: Full=Selenium donor protein 2; AltName: Full=Selenophosphate synthase 2;+++[B4E093_HUMAN|Unreviewed]SubName: Full=Selenophosphate synthetase 2 {ECO:0000313|EMBL:EAW52246.1}; SubName: Full=cDNA FLJ53520, highly similar to Selenide, water dikinase 2 {ECO:0000313|EMBL:BAG64355.1};"]
[2295,"'FOXF2'",118,76,97,null,"H00830///Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV)",null,null,"GO:0005667///transcription factor complex+++GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0030198///extracellular matrix organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042249///establishment of planar polarity of embryonic epithelium+++GO:0060021///roof of mouth development+++GO:0048806///genitalia development+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048566///embryonic digestive tract development+++GO:0045893///positive regulation of transcription, DNA-templated","IPR001766///Fork head domain+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR018122///Fork head domain conserved site1+++IPR030456///Fork head domain conserved site 2","[FOXF2_HUMAN|Reviewed]RecName: Full=Forkhead box protein F2; AltName: Full=Forkhead-related activator 2; Short=FREAC-2; AltName: Full=Forkhead-related protein FKHL6; AltName: Full=Forkhead-related transcription factor 2;"]
[22983,"'MAST1'",460,485,472.5,"04380///Osteoclast differentiation+++04668///TNF signaling pathway","H01463///Mycosis fungoides",null,null,"GO:0000785///chromatin+++GO:0000790///nuclear chromatin+++GO:0005856///cytoskeleton+++GO:0035976///transcription factor AP-1 complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005622///intracellular","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001077///proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003714///transcription corepressor activity+++GO:0005524///ATP binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0000287///magnesium ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0003713///transcription coactivator activity+++GO:0008134///transcription factor binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0009612///response to mechanical stimulus+++GO:0033687///osteoblast proliferation+++GO:0006468///protein phosphorylation+++GO:0060716///labyrinthine layer blood vessel development+++GO:0051591///response to cAMP+++GO:0051726///regulation of cell cycle+++GO:0032496///response to lipopolysaccharide+++GO:0009314///response to radiation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0046697///decidualization+++GO:0034097///response to cytokine+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007010///cytoskeleton organization+++GO:0042127///regulation of cell proliferation+++GO:0001570///vasculogenesis+++GO:0045597///positive regulation of cell differentiation+++GO:0032870///cellular response to hormone stimulus+++GO:0030316///osteoclast differentiation+++GO:0001649///osteoblast differentiation+++GO:0060136///embryonic process involved in female pregnancy+++GO:0071277///cellular response to calcium ion+++GO:0010941///regulation of cell death+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0035556///intracellular signal transduction+++GO:0001829///trophectodermal cell differentiation+++GO:0042493///response to drug+++GO:0018105///peptidyl-serine phosphorylation","IPR037711///Microtubule-associated serine/threonine-protein kinase, catalytic domain+++IPR023142///Microtubule-associated serine/threonine-protein kinase, pre-PK domain superfamily+++IPR028777///Microtubule-associated serine/threonine-protein kinase 1+++IPR001478///PDZ domain+++IPR036034///PDZ superfamily+++IPR015022///Microtubule-associated serine/threonine-protein kinase, domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR000961///AGC-kinase, C-terminal+++IPR000719///Protein kinase domain","[MAST1_HUMAN|Reviewed]RecName: Full=Microtubule-associated serine/threonine-protein kinase 1; EC=2.7.11.1; AltName: Full=Syntrophin-associated serine/threonine-protein kinase;"]
[23,"'ABCF1'",1477,1137,1307,{"$nulls":4},"GO:0005635///nuclear envelope+++GO:0042788///polysomal ribosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005840///ribosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0016887///ATPase activity+++GO:0043022///ribosome binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0008135///translation factor activity, RNA binding+++GO:0008494///translation activator activity+++GO:0005524///ATP binding+++GO:0003723///RNA binding","GO:0055085///transmembrane transport+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0042254///ribosome biogenesis+++GO:0006954///inflammatory response+++GO:0045727///positive regulation of translation","IPR003439///ABC transporter-like+++IPR032781///ABC-transporter extension domain+++IPR017871///ABC transporter, conserved site+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003593///AAA+ ATPase domain","[ABCF1_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family F member 1; AltName: Full=ATP-binding cassette 50; AltName: Full=TNF-alpha-stimulated ABC protein;+++[A0A0G2JIC2_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000397199};+++[A0A1U9X609_HUMAN|Unreviewed]SubName: Full=ABCF1 {ECO:0000313|EMBL:AQY76226.1};+++[A0PJ72_HUMAN|Unreviewed]SubName: Full=ABCF1 protein {ECO:0000313|EMBL:AAH16772.1}; Flags: Fragment;+++[F5GYK6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000440893}; Flags: Fragment;+++[H0YGW7_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000445100}; Flags: Fragment;+++[L0R6B8_HUMAN|Unreviewed]SubName: Full=Alternative protein ABCF1 {ECO:0000313|EMBL:CCO13667.1};+++[Q2L6I2_HUMAN|Unreviewed]SubName: Full=ABC50 protein {ECO:0000313|EMBL:BAF31263.1}; SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 1 {ECO:0000313|EMBL:BAE78612.1}; SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 1, isoform CRA_a {ECO:0000313|EMBL:EAX03300.1};+++[Q5STZ8_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|Ensembl:ENSP00000405512}; Flags: Fragment;"]
[23019,"'CNOT1'",1845,2664,2254.5,"03018///RNA degradation",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0030014///CCR4-NOT complex+++GO:0000932///P-body+++GO:0005634///nucleus","GO:0030331///estrogen receptor binding+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0070016///armadillo repeat domain binding+++GO:0005515///protein binding+++GO:0042974///retinoic acid receptor binding+++GO:0019904///protein domain specific binding+++GO:0003723///RNA binding+++GO:0032947///protein-containing complex scaffold activity","GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0031047///gene silencing by RNA+++GO:2000036///regulation of stem cell population maintenance+++GO:0061014///positive regulation of mRNA catabolic process+++GO:0007275///multicellular organism development+++GO:0006417///regulation of translation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0017148///negative regulation of translation+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0035195///gene silencing by miRNA+++GO:0060213///positive regulation of nuclear-transcribed mRNA poly(A) tail shortening+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR038535///CCR4-NOT subunit 1, TTP binding domain superfamily+++IPR024557///CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819+++IPR032194///CCR4-NOT transcription complex subunit 1, HEAT repeat+++IPR032193///CCR4-NOT transcription complex subunit 1, TTP binding domain+++IPR032191///CCR4-NOT transcription complex subunit 1, CAF1-binding domain+++IPR007196///CCR4-Not complex component, Not1, C-terminal+++IPR016021///MIF4G-like domain superfamily","[CNOT1_HUMAN|Reviewed]RecName: Full=CCR4-NOT transcription complex subunit 1; AltName: Full=CCR4-associated factor 1; AltName: Full=Negative regulator of transcription subunit 1 homolog; Short=NOT1H; Short=hNOT1;+++[H3BMH0_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000454377}; Flags: Fragment;+++[H3BMZ2_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000454611}; Flags: Fragment;+++[H3BNB1_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000454763}; Flags: Fragment;+++[H3BPF1_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000455289}; Flags: Fragment;+++[H3BR89_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000456131}; Flags: Fragment;+++[H3BT18_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000456975}; Flags: Fragment;+++[H3BTH2_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000457173}; Flags: Fragment;+++[H3BU44_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000457460};+++[H3BVC9_HUMAN|Unreviewed]SubName: Full=CCR4-NOT transcription complex subunit 1 {ECO:0000313|Ensembl:ENSP00000458057}; Flags: Fragment;"]
[23035,"'PHLPP2'",80,131,105.5,"04151///PI3K-Akt signaling pathway",{"$nulls":3},"GO:0001917///photoreceptor inner segment+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0042622///photoreceptor outer segment membrane","GO:0003824///catalytic activity+++GO:0046872///metal ion binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity","GO:0006470///protein dephosphorylation+++GO:0021766///hippocampus development","IPR025875///Leucine rich repeat 4+++IPR032675///Leucine-rich repeat domain superfamily+++IPR001932///PPM-type phosphatase domain+++IPR003591///Leucine-rich repeat, typical subtype+++IPR036457///PPM-type phosphatase domain superfamily+++IPR001611///Leucine-rich repeat","[PHLP2_HUMAN|Reviewed]RecName: Full=PH domain leucine-rich repeat-containing protein phosphatase 2; EC=3.1.3.16 {ECO:0000269|PubMed:17386267, ECO:0000269|PubMed:24892992}; AltName: Full=PH domain leucine-rich repeat-containing protein phosphatase-like; Short=PHLPP-like;+++[A1L3A0_HUMAN|Unreviewed]SubName: Full=PHLPPL protein {ECO:0000313|EMBL:AAI29984.1};+++[H3BMS5_HUMAN|Unreviewed]SubName: Full=PH domain leucine-rich repeat-containing protein phosphatase 2 {ECO:0000313|Ensembl:ENSP00000454519};+++[H3BS75_HUMAN|Unreviewed]SubName: Full=PH domain leucine-rich repeat-containing protein phosphatase 2 {ECO:0000313|Ensembl:ENSP00000456572}; Flags: Fragment;+++[I3L187_HUMAN|Unreviewed]SubName: Full=PH domain leucine-rich repeat-containing protein phosphatase 2 {ECO:0000313|Ensembl:ENSP00000458660}; Flags: Fragment;+++[Q3ZCW4_HUMAN|Unreviewed]SubName: Full=PHLPPL protein {ECO:0000313|EMBL:AAH35267.1}; Flags: Fragment;"]
[23052,"'ENDOD1'",583,626,604.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0016020///membrane","GO:0004519///endonuclease activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0004518///nuclease activity","GO:0002576///platelet degranulation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","IPR001604///DNA/RNA non-specific endonuclease+++IPR020821///Extracellular Endonuclease, subunit A+++IPR039015///Endonuclease domain-containing 1 protein","[ENDD1_HUMAN|Reviewed]RecName: Full=Endonuclease domain-containing 1 protein; EC=3.1.30.-; Flags: Precursor;"]
[23070,"'CMTR1'",690,685,687.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",null,null,"R03922///S-adenosyl-L-methionine:5-(N7-methyl 5-triphosphoguanosine)-(purine-ribonucleotide)-[mRNA] 2-O-methyltransferase   S-Adenosyl-L-methionine + m7G(5')pppR-mRNA <=> S-Adenosyl-L-homocysteine + m7G(5')pppRm-mRNA","GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0004483///mRNA (nucleoside-2'-O-)-methyltransferase activity+++GO:0003676///nucleic acid binding+++GO:0008168///methyltransferase activity","GO:0080009///mRNA methylation+++GO:0006397///mRNA processing+++GO:0032259///methylation+++GO:0097309///cap1 mRNA methylation+++GO:0006370///7-methylguanosine mRNA capping","IPR002877///Ribosomal RNA methyltransferase FtsJ domain+++IPR000467///G-patch domain+++IPR025816///RrmJ-type ribose 2-O-methyltransferase domain+++IPR001202///WW domain+++IPR030376///Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[CMTR1_HUMAN|Reviewed]RecName: Full=Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; EC=2.1.1.57 {ECO:0000269|PubMed:21310715}; AltName: Full=Cap methyltransferase 1; AltName: Full=Cap1 2'O-ribose methyltransferase 1; Short=MTr1; Short=hMTr1; AltName: Full=FtsJ methyltransferase domain-containing protein 2; AltName: Full=Interferon-stimulated gene 95 kDa protein; Short=ISG95;+++[H0Y4T0_HUMAN|Unreviewed]SubName: Full=Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 {ECO:0000313|Ensembl:ENSP00000393893}; Flags: Fragment;+++[H0YCQ1_HUMAN|Unreviewed]SubName: Full=Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 {ECO:0000313|Ensembl:ENSP00000432114}; Flags: Fragment;+++[Q5T7F5_HUMAN|Unreviewed]SubName: Full=Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 {ECO:0000313|Ensembl:ENSP00000414233}; Flags: Fragment;"]
[23089,"'PEG10'",329,501,415,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0030154///cell differentiation+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0006915///apoptotic process+++GO:0001890///placenta development","IPR032567///LDOC1-related+++IPR036875///Zinc finger, CCHC-type superfamily+++IPR032549///Domain of unknown function DUF4939+++IPR021109///Aspartic peptidase domain superfamily+++IPR001878///Zinc finger, CCHC-type","[PEG10_HUMAN|Reviewed]RecName: Full=Retrotransposon-derived protein PEG10; AltName: Full=Embryonal carcinoma differentiation-regulated protein; AltName: Full=Mammalian retrotransposon-derived protein 2; AltName: Full=Myelin expression factor 3-like protein 1; Short=MEF3-like protein 1; AltName: Full=Paternally expressed gene 10 protein; AltName: Full=Retrotransposon gag domain-containing protein 3; AltName: Full=Retrotransposon-derived gag-like polyprotein; AltName: Full=Ty3/Gypsy-like protein;+++[A0A087WUL4_HUMAN|Unreviewed]SubName: Full=Retrotransposon-derived protein PEG10 {ECO:0000313|Ensembl:ENSP00000478744};+++[A0A087WX23_HUMAN|Unreviewed]SubName: Full=Retrotransposon-derived protein PEG10 {ECO:0000313|Ensembl:ENSP00000480676};+++[A0A087WXK2_HUMAN|Unreviewed]SubName: Full=Retrotransposon-derived protein PEG10 {ECO:0000313|Ensembl:ENSP00000481101};+++[A0A087WYS2_HUMAN|Unreviewed]SubName: Full=Retrotransposon-derived protein PEG10 {ECO:0000313|Ensembl:ENSP00000482046}; Flags: Fragment;+++[A0A087WZG9_HUMAN|Unreviewed]SubName: Full=Retrotransposon-derived protein PEG10 {ECO:0000313|Ensembl:ENSP00000482653};+++[B4DSP0_HUMAN|Unreviewed]SubName: Full=HCG1642748, isoform CRA_b {ECO:0000313|EMBL:EAW76781.1}; SubName: Full=Retrotransposon-derived protein PEG10 {ECO:0000313|Ensembl:ENSP00000418944}; SubName: Full=cDNA FLJ56638, highly similar to Homo sapiens paternally expressed 10 (PEG10), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61702.1};"]
[23107,"'MRPS27'",390,345,367.5,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005743///mitochondrial inner membrane+++GO:0005737///cytoplasm+++GO:0005840///ribosome","GO:0005515///protein binding+++GO:0000049///tRNA binding+++GO:0019843///rRNA binding+++GO:0003723///RNA binding+++GO:0097177///mitochondrial ribosome binding","GO:0008283///cell proliferation+++GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:0006417///regulation of translation+++GO:0070131///positive regulation of mitochondrial translation","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR002885///Pentatricopeptide repeat+++IPR019266///28S ribosomal protein S27, mitochondrial+++IPR034913///MRPS27/PTCD2","[RT27_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S27, mitochondrial {ECO:0000305}; Short=MRP-S27; Short=S27mt; AltName: Full=Mitochondrial ribosomal protein S27 {ECO:0000312|HGNC:HGNC:14512}; AltName: Full=Mitochondrial small ribosomal subunit protein mS27 {ECO:0000303|PubMed:25838379}; Flags: Precursor;+++[A0A024RAJ1_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein S27, isoform CRA_a {ECO:0000313|EMBL:EAW95703.1};+++[D6RH20_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S27, mitochondrial {ECO:0000313|Ensembl:ENSP00000426176}; Flags: Fragment;+++[D6RJC7_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S27, mitochondrial {ECO:0000313|Ensembl:ENSP00000427237};+++[E5RJ73_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S27, mitochondrial {ECO:0000313|Ensembl:ENSP00000430590};+++[G5EA06_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S27, mitochondrial {ECO:0000313|Ensembl:ENSP00000428120}; SubName: Full=Mitochondrial ribosomal protein S27, isoform CRA_b {ECO:0000313|EMBL:EAW95702.1};+++[Q6PKB3_HUMAN|Unreviewed]SubName: Full=MRPS27 protein {ECO:0000313|EMBL:AAH03632.1}; Flags: Fragment;"]
[23126,"'POGZ'",494,753.83,623.915,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0051301///cell division+++GO:0051382///kinetochore assembly+++GO:0007064///mitotic sister chromatid cohesion","IPR004875///DDE superfamily endonuclease domain+++IPR013087///Zinc finger C2H2-type+++IPR006600///HTH CenpB-type DNA-binding domain+++IPR009057///Homeobox-like domain superfamily+++IPR036236///Zinc finger C2H2 superfamily","[POGZ_HUMAN|Reviewed]RecName: Full=Pogo transposable element with ZNF domain; AltName: Full=Suppressor of hairy wing homolog 5; AltName: Full=Zinc finger protein 280E; AltName: Full=Zinc finger protein 635;+++[A0A0G2JHK5_HUMAN|Unreviewed]SubName: Full=Pogo transposable element with ZNF domain {ECO:0000313|Ensembl:ENSP00000390156}; Flags: Fragment;+++[A0A2S0X0J5_HUMAN|Unreviewed]SubName: Full=Pogo transposable element derived with ZNF domain {ECO:0000313|EMBL:AWB97129.1}; Flags: Fragment;+++[A0A2S0X0P7_HUMAN|Unreviewed]SubName: Full=NPC intracellular cholesterol transporter 1 {ECO:0000313|EMBL:AWB97130.1}; Flags: Fragment;+++[A6PW30_HUMAN|Unreviewed]SubName: Full=Pogo transposable element with ZNF domain {ECO:0000313|Ensembl:ENSP00000395332}; Flags: Fragment;+++[E9PIR8_HUMAN|Unreviewed]SubName: Full=Pogo transposable element with ZNF domain {ECO:0000313|Ensembl:ENSP00000433934}; Flags: Fragment;+++[E9PJY9_HUMAN|Unreviewed]SubName: Full=Pogo transposable element with ZNF domain {ECO:0000313|Ensembl:ENSP00000433637}; Flags: Fragment;+++[H0YCT3_HUMAN|Unreviewed]SubName: Full=Pogo transposable element with ZNF domain {ECO:0000313|Ensembl:ENSP00000432295}; Flags: Fragment;+++[H7C238_HUMAN|Unreviewed]SubName: Full=Pogo transposable element with ZNF domain {ECO:0000313|Ensembl:ENSP00000403955}; Flags: Fragment;+++[M0R2X2_HUMAN|Unreviewed]SubName: Full=Pogo transposable element with ZNF domain {ECO:0000313|Ensembl:ENSP00000472860}; Flags: Fragment;"]
[23141,"'ANKLE2'",1582,1624,1603,null,"H00269///Primary microcephaly (MCPH)",null,null,"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0051721///protein phosphatase 2A binding+++GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity","GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0007049///cell cycle+++GO:0050790///regulation of catalytic activity+++GO:0043066///negative regulation of apoptotic process+++GO:0007084///mitotic nuclear envelope reassembly+++GO:0007417///central nervous system development+++GO:0051301///cell division+++GO:0042326///negative regulation of phosphorylation+++GO:0035307///positive regulation of protein dephosphorylation","IPR037056///Ribonuclease H1, N-terminal domain superfamily+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR011015///LEM/LEM-like domain superfamily+++IPR035006///Ankyrin repeat and LEM domain-containing protein 2, LEM domain+++IPR003887///LEM domain+++IPR020683///Ankyrin repeat-containing domain+++IPR011320///Ribonuclease H1, N-terminal+++IPR035007///Ankyrin repeat and LEM domain-containing protein 2","[ANKL2_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and LEM domain-containing protein 2; AltName: Full=LEM domain-containing protein 4;+++[A0A220T1R9_HUMAN|Unreviewed]SubName: Full=ANKLE2 {ECO:0000313|EMBL:ASK40097.1};+++[F5H1D4_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and LEM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000445760}; Flags: Fragment;+++[F5H6J0_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and LEM domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000437585}; Flags: Fragment;"]
[23160,"'WDR43'",429,472,450.5,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0001650///fibrillar center+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0042254///ribosome biogenesis+++GO:0006364///rRNA processing+++GO:2000234///positive regulation of rRNA processing","IPR001680///WD40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR007148///Small-subunit processome, Utp12+++IPR036322///WD40-repeat-containing domain superfamily+++IPR017986///WD40-repeat-containing domain","[WDR43_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 43; AltName: Full=U3 small nucleolar RNA-associated protein 5 homolog;+++[C9IZK7_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 43 {ECO:0000313|Ensembl:ENSP00000296126}; Flags: Fragment;+++[C9JEE7_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 43 {ECO:0000313|Ensembl:ENSP00000415355}; Flags: Fragment;+++[C9JH61_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 43 {ECO:0000313|Ensembl:ENSP00000390363}; Flags: Fragment;+++[Q8TB67_HUMAN|Unreviewed]SubName: Full=WDR43 protein {ECO:0000313|EMBL:AAH24234.1}; Flags: Fragment;"]
[23174,"'ZCCHC14'",432,557,494.5,{"$nulls":5},"GO:0003676///nucleic acid binding+++GO:0035091///phosphatidylinositol binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding",null,"IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR037632///ZCCH14, SAM domain+++IPR036875///Zinc finger, CCHC-type superfamily+++IPR001878///Zinc finger, CCHC-type+++IPR036871///PX domain superfamily","[ZCH14_HUMAN|Reviewed]RecName: Full=Zinc finger CCHC domain-containing protein 14; AltName: Full=BDG-29;+++[H3BS18_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000456499}; Flags: Fragment;"]
[23191,"'CYFIP1'",1216,1323,1269.5,"04810///Regulation of actin cytoskeleton+++03013///RNA transport",{"$nulls":3},"GO:0043005///neuron projection+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0045202///synapse+++GO:0090725///peripheral region of growth cone+++GO:0044294///dendritic growth cone+++GO:0090724///central region of growth cone+++GO:0043197///dendritic spine+++GO:0098794///postsynapse+++GO:0032433///filopodium tip+++GO:0005845///mRNA cap binding complex+++GO:0034774///secretory granule lumen+++GO:0030054///cell junction+++GO:0035580///specific granule lumen+++GO:0044295///axonal growth cone+++GO:1904724///tertiary granule lumen+++GO:0005925///focal adhesion+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0043195///terminal bouton+++GO:0043025///neuronal cell body+++GO:0042995///cell projection+++GO:0060076///excitatory synapse+++GO:0031209///SCAR complex+++GO:0030027///lamellipodium+++GO:0005576///extracellular region","GO:0048365///Rac GTPase binding+++GO:0003779///actin binding+++GO:0051015///actin filament binding+++GO:0000340///RNA 7-methylguanosine cap binding+++GO:0005515///protein binding+++GO:0045182///translation regulator activity","GO:2000601///positive regulation of Arp2/3 complex-mediated actin nucleation+++GO:0030154///cell differentiation+++GO:0043312///neutrophil degranulation+++GO:0050772///positive regulation of axonogenesis+++GO:0097484///dendrite extension+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0051602///response to electrical stimulus+++GO:0099563///modification of synaptic structure+++GO:0051388///positive regulation of neurotrophin TRK receptor signaling pathway+++GO:0032869///cellular response to insulin stimulus+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:0007275///multicellular organism development+++GO:1905274///regulation of modification of postsynaptic actin cytoskeleton+++GO:0006417///regulation of translation+++GO:0030032///lamellipodium assembly+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:1900029///positive regulation of ruffle assembly+++GO:0030031///cell projection assembly+++GO:0007399///nervous system development+++GO:0045773///positive regulation of axon extension+++GO:0007411///axon guidance+++GO:0048675///axon extension+++GO:0031529///ruffle organization+++GO:0031175///neuron projection development+++GO:1900006///positive regulation of dendrite development+++GO:1903422///negative regulation of synaptic vesicle recycling+++GO:0000902///cell morphogenesis+++GO:0008360///regulation of cell shape+++GO:0050890///cognition+++GO:0016601///Rac protein signal transduction","IPR008081///Cytoplasmic FMR1-interacting+++IPR009828///Protein of unknown function DUF1394","[CYFP1_HUMAN|Reviewed]RecName: Full=Cytoplasmic FMR1-interacting protein 1; AltName: Full=Specifically Rac1-associated protein 1; Short=Sra-1; AltName: Full=p140sra-1;+++[A0A087WU52_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000478377}; Flags: Fragment;+++[A0A087WVZ5_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000479802}; Flags: Fragment;+++[A0A087WWL1_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000480307}; Flags: Fragment;+++[A0A087WWY5_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000480596};+++[A0A087WZ89_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000482459}; Flags: Fragment;+++[A0A0G2JQH3_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485841}; Flags: Fragment;+++[A0A0G2JQT1_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000486145}; Flags: Fragment;+++[A0A0G2JR96_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000486555}; Flags: Fragment;+++[A0A0G2JRF5_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000486724};+++[A0A0G2JRP0_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000486951}; Flags: Fragment;+++[A0A0G2JRV9_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000487107}; Flags: Fragment;+++[A0A0G2JRX2_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000487156}; Flags: Fragment;+++[H0YL50_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000453060}; Flags: Fragment;+++[X5D2F4_HUMAN|Unreviewed]SubName: Full=Cytoplasmic FMR1 interacting protein 1 isoform A {ECO:0000313|EMBL:AHW56459.1}; Flags: Fragment;"]
[23209,"'MLC1'",2,0,1,null,"H00875///Megalencephalic leukoencephalopathy with subcortical cysts (MLC)",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005911///cell-cell junction+++GO:0030136///clathrin-coated vesicle+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0055037///recycling endosome+++GO:0005764///lysosome+++GO:0005769///early endosome+++GO:0016324///apical plasma membrane+++GO:0005901///caveola+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0008565///protein transporter activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding","GO:0051259///protein complex oligomerization+++GO:0071397///cellular response to cholesterol+++GO:0015031///protein transport+++GO:0006811///ion transport+++GO:0047484///regulation of response to osmotic stress+++GO:0032388///positive regulation of intracellular transport+++GO:0072584///caveolin-mediated endocytosis+++GO:0016192///vesicle-mediated transport","IPR033280///Membrane protein MLC1","[MLC1_HUMAN|Reviewed]RecName: Full=Membrane protein MLC1;+++[A0A024R4V4_HUMAN|Unreviewed]SubName: Full=Megalencephalic leukoencephalopathy with subcortical cysts 1, isoform CRA_a {ECO:0000313|EMBL:EAW73491.1};+++[A6PVC3_HUMAN|Unreviewed]SubName: Full=Membrane protein MLC1 {ECO:0000313|Ensembl:ENSP00000401385}; Flags: Fragment;+++[Q6NSL6_HUMAN|Unreviewed]SubName: Full=Megalencephalic leukoencephalopathy with subcortical cysts 1 {ECO:0000313|EMBL:AAH70042.1};"]
[23223,"'RRP12'",1010,961,985.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0031965///nuclear membrane+++GO:0005730///nucleolus","GO:0003723///RNA binding",null,"IPR012978///Uncharacterised domain NUC173+++IPR016024///Armadillo-type fold","[RRP12_HUMAN|Reviewed]RecName: Full=RRP12-like protein;+++[A0A087WYW2_HUMAN|Unreviewed]SubName: Full=RRP12-like protein {ECO:0000313|Ensembl:ENSP00000482139}; Flags: Fragment;+++[A0A087X0G0_HUMAN|Unreviewed]SubName: Full=RRP12-like protein {ECO:0000313|Ensembl:ENSP00000483365}; Flags: Fragment;+++[A0A087X1U8_HUMAN|Unreviewed]SubName: Full=RRP12-like protein {ECO:0000313|Ensembl:ENSP00000484474}; Flags: Fragment;+++[B3KMR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12434 fis, clone NT2RM1000037, highly similar to Homo sapiens KIAA0690 protein {ECO:0000313|EMBL:BAG51077.1};+++[H7C1M8_HUMAN|Unreviewed]SubName: Full=RRP12-like protein {ECO:0000313|Ensembl:ENSP00000401102}; Flags: Fragment;"]
[23240,"'TMEM131L'",218.98,272.19,245.585,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0003964///RNA-directed DNA polymerase activity","GO:0033088///negative regulation of immature T cell proliferation in thymus+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway","IPR022113///Transmembrane protein 131-like domain+++IPR039877///Transmembrane protein 131-like","[T131L_HUMAN|Reviewed]RecName: Full=Transmembrane protein 131-like {ECO:0000312|HGNC:HGNC:29146}; Flags: Precursor;+++[B3KU55_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39219 fis, clone OCBBF2006849, weakly similar to Transmembrane protein 131 {ECO:0000313|EMBL:BAG53317.1};+++[F8WEQ2_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 131-like {ECO:0000313|Ensembl:ENSP00000413054};+++[H0Y2M0_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 131-like {ECO:0000313|Ensembl:ENSP00000240487}; Flags: Fragment;+++[L0R4Z7_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0922 {ECO:0000313|EMBL:CCO13758.1};"]
[23256,"'SCFD1'",393,476,434.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005798///Golgi-associated vesicle+++GO:0005794///Golgi apparatus+++GO:0032580///Golgi cisterna membrane+++GO:0016021///integral component of membrane+++GO:0005801///cis-Golgi network","GO:0047485///protein N-terminus binding+++GO:0044877///protein-containing complex binding+++GO:0019905///syntaxin binding+++GO:0005515///protein binding","GO:0000902///cell morphogenesis+++GO:0001666///response to hypoxia+++GO:0060628///regulation of ER to Golgi vesicle-mediated transport+++GO:0009636///response to toxic substance+++GO:0006892///post-Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:1901998///toxin transport+++GO:1902902///negative regulation of autophagosome assembly+++GO:0051223///regulation of protein transport+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006904///vesicle docking involved in exocytosis","IPR001619///Sec1-like protein+++IPR036045///Sec1-like superfamily+++IPR027482///Sec1-like, domain 2","[SCFD1_HUMAN|Reviewed]RecName: Full=Sec1 family domain-containing protein 1; AltName: Full=SLY1 homolog; Short=Sly1p; AltName: Full=Syntaxin-binding protein 1-like 2;+++[B7Z5N7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58612, highly similar to Sec1 family domain-containing protein 1 {ECO:0000313|EMBL:BAH12973.1};+++[B7Z738_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57213, highly similar to Sec1 family domain-containing protein 1 {ECO:0000313|EMBL:BAH13474.1};+++[G3V2M8_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450755}; Flags: Fragment;+++[G3V363_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000451064};+++[G3V3K9_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000451298};+++[G3V4I1_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000451811};+++[G3V551_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452178};+++[G3V5E2_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452308}; Flags: Fragment;+++[G3V5F3_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452323};+++[H0YIZ7_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000450546}; Flags: Fragment;+++[H0YJS6_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452046}; Flags: Fragment;+++[H0YJY1_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000452448}; Flags: Fragment;+++[J3KNG4_HUMAN|Unreviewed]SubName: Full=Sec1 family domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000309417};"]
[23274,"'CLEC16A'",741,990,865.5,"04612///Antigen processing and presentation+++05145///Toxoplasmosis+++04140///Autophagy - animal+++05152///Tuberculosis+++04137///Mitophagy - animal+++05340///Primary immunodeficiency+++05164///Influenza A","H00408///Type I diabetes mellitus",null,null,"GO:0036020///endolysosome membrane+++GO:0016020///membrane+++GO:0005770///late endosome+++GO:0031982///vesicle+++GO:0010008///endosome membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005765///lysosomal membrane+++GO:0005829///cytosol+++GO:0005768///endosome+++GO:0005764///lysosome","GO:0003674///molecular_function+++GO:0017137///Rab GTPase binding","GO:0008333///endosome to lysosome transport+++GO:1901097///negative regulation of autophagosome maturation+++GO:0016197///endosomal transport+++GO:0006914///autophagy+++GO:1904766///negative regulation of macroautophagy by TORC1 signaling+++GO:0009267///cellular response to starvation+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1901525///negative regulation of mitophagy+++GO:1904263///positive regulation of TORC1 signaling+++GO:1901098///positive regulation of autophagosome maturation","IPR019155///CLEC16A/TT9, N-terminal+++IPR039272///CLEC16A/TT9","[CL16A_HUMAN|Reviewed]RecName: Full=Protein CLEC16A {ECO:0000305}; AltName: Full=C-type lectin domain family 16 member A {ECO:0000312|HGNC:HGNC:29013};+++[A0A2R8YDG4_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000493756}; Flags: Fragment;+++[H7BXG1_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000261657}; Flags: Fragment;+++[H7BZI2_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000389743}; Flags: Fragment;+++[H7BZJ9_HUMAN|Unreviewed]SubName: Full=Protein CLEC16A {ECO:0000313|Ensembl:ENSP00000389963}; Flags: Fragment;"]
[23275,"'POFUT2'",2142,2155,2148.5,"00514///Other types of O-glycan biosynthesis","H00944///Dowling-Degos disease",null,"R09295///GDP-beta-L-fucose:polypeptide O-alpha-L-fucosyltransferase   GDP-L-fucose + [Protein]-L-serine <=> GDP + G13052","GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0046922///peptide-O-fucosyltransferase activity+++GO:0008417///fucosyltransferase activity","GO:0010717///regulation of epithelial to mesenchymal transition+++GO:0036066///protein O-linked fucosylation+++GO:0001707///mesoderm formation+++GO:0051046///regulation of secretion+++GO:0005975///carbohydrate metabolic process+++GO:0036065///fucosylation+++GO:0006486///protein glycosylation+++GO:0006004///fucose metabolic process+++GO:0010468///regulation of gene expression","IPR019378///GDP-fucose protein O-fucosyltransferase","[OFUT2_HUMAN|Reviewed]RecName: Full=GDP-fucose protein O-fucosyltransferase 2; EC=2.4.1.221; AltName: Full=Peptide-O-fucosyltransferase 2; Short=O-FucT-2; Flags: Precursor;+++[A0A0C4DGX7_HUMAN|Unreviewed]SubName: Full=GDP-fucose protein O-fucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000482216};+++[H7C2T5_HUMAN|Unreviewed]SubName: Full=GDP-fucose protein O-fucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000407635}; Flags: Fragment;+++[S6FMI4_HUMAN|Unreviewed]SubName: Full=Protein O-fucosyltransferase 2 {ECO:0000313|EMBL:CDG37811.1}; Flags: Fragment;+++[S6FW71_HUMAN|Unreviewed]SubName: Full=GDP-fucose protein O-fucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000478168}; SubName: Full=Protein O-fucosyltransferase 2 {ECO:0000313|EMBL:CDG37810.1};"]
[23295,"'MGRN1'",4669.23,4761.13,4715.18,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005737///cytoplasm","GO:0016874///ligase activity+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0061630///ubiquitin protein ligase activity","GO:0045879///negative regulation of smoothened signaling pathway+++GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0006513///protein monoubiquitination+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0008333///endosome to lysosome transport","IPR001841///Zinc finger, RING-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type","[MGRN1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MGRN1; EC=2.3.2.27; AltName: Full=Mahogunin RING finger protein 1; AltName: Full=RING finger protein 156; AltName: Full=RING-type E3 ubiquitin transferase MGRN1 {ECO:0000305};+++[B4DR12_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MGRN1 {ECO:0000313|Ensembl:ENSP00000443810}; SubName: Full=cDNA FLJ60814, highly similar to Probable E3 ubiquitin-protein ligase MGRN1 {ECO:0000313|EMBL:BAG61124.1};+++[K7EIM7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MGRN1 {ECO:0000313|Ensembl:ENSP00000464811}; Flags: Fragment;+++[K7EJN3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MGRN1 {ECO:0000313|Ensembl:ENSP00000465249}; Flags: Fragment;+++[K7EPJ5_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MGRN1 {ECO:0000313|Ensembl:ENSP00000467414}; Flags: Fragment;+++[K7ERA1_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase MGRN1 {ECO:0000313|Ensembl:ENSP00000468171}; Flags: Fragment;"]
[23313,"'KIAA0930'",2216,2049,2132.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","IPR019141///Protein of unknown function DUF2045","[K0930_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0930;+++[B0AZU2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55491 {ECO:0000313|EMBL:BAH12486.1}; SubName: Full=cDNA, FLJ79532 {ECO:0000313|EMBL:BAF98774.1};+++[B0QY16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0930 {ECO:0000313|Ensembl:ENSP00000399125}; Flags: Fragment;+++[B0QY18_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0930 {ECO:0000313|Ensembl:ENSP00000403030}; Flags: Fragment;+++[B0QY20_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0930 {ECO:0000313|Ensembl:ENSP00000392752}; Flags: Fragment;+++[F8WD08_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0930 {ECO:0000313|Ensembl:ENSP00000395994};+++[H7C1U5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0930 {ECO:0000313|Ensembl:ENSP00000402514}; Flags: Fragment;+++[Q8IUY4_HUMAN|Unreviewed]SubName: Full=C22orf9 protein {ECO:0000313|EMBL:AAH38414.1}; Flags: Fragment;+++[V9GYW7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0930 {ECO:0000313|Ensembl:ENSP00000477148};+++[V9GZ62_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0930 {ECO:0000313|Ensembl:ENSP00000477454};"]
[23331,"'TTC28'",643,810,726.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0000922///spindle pole+++GO:0072686///mitotic spindle+++GO:0005815///microtubule organizing center+++GO:0030496///midbody+++GO:0005856///cytoskeleton","GO:0019900///kinase binding","GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0007346///regulation of mitotic cell cycle","IPR013026///Tetratricopeptide repeat-containing domain+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR024983///CHAT domain+++IPR019734///Tetratricopeptide repeat","[TTC28_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 28; Short=TPR repeat protein 28; AltName: Full=TPR repeat-containing big gene cloned at Keio;+++[A0A087WW06_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 28 {ECO:0000313|Ensembl:ENSP00000479834};+++[B0QYP4_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 28 {ECO:0000313|Ensembl:ENSP00000388788}; Flags: Fragment;+++[B0QYP5_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 28 {ECO:0000313|Ensembl:ENSP00000410244}; Flags: Fragment;+++[L8E8S5_HUMAN|Unreviewed]SubName: Full=Alternative protein TTC28 {ECO:0000313|EMBL:CCQ43126.1};"]
[2335,"'FN1'",167809,310237,239023,"04933///AGE-RAGE signaling pathway in diabetic complications+++05165///Human papillomavirus infection+++05200///Pathways in cancer+++05205///Proteoglycans in cancer+++05222///Small cell lung cancer+++04510///Focal adhesion+++05146///Amoebiasis+++04151///PI3K-Akt signaling pathway+++05100///Bacterial invasion of epithelial cells+++04512///ECM-receptor interaction+++04810///Regulation of actin cytoskeleton","H01260///Glomerulopathy with fibronectin deposits (GFND)",null,null,"GO:0005577///fibrinogen complex+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0070062///extracellular exosome+++GO:0005604///basement membrane+++GO:0005576///extracellular region+++GO:0005788///endoplasmic reticulum lumen+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0031012///extracellular matrix+++GO:0016324///apical plasma membrane+++GO:0031093///platelet alpha granule lumen+++GO:0072562///blood microparticle","GO:0051087///chaperone binding+++GO:0043394///proteoglycan binding+++GO:0005102///signaling receptor binding+++GO:0097718///disordered domain specific binding+++GO:0019899///enzyme binding+++GO:0005518///collagen binding+++GO:0005201///extracellular matrix structural constituent+++GO:0008201///heparin binding+++GO:0002020///protease binding+++GO:0008022///protein C-terminus binding+++GO:0042802///identical protein binding+++GO:0005178///integrin binding+++GO:0016504///peptidase activator activity+++GO:0005515///protein binding","GO:0008284///positive regulation of cell proliferation+++GO:0033622///integrin activation+++GO:0006953///acute-phase response+++GO:0007161///calcium-independent cell-matrix adhesion+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0001525///angiogenesis+++GO:0044267///cellular protein metabolic process+++GO:0009611///response to wounding+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0007155///cell adhesion+++GO:0043687///post-translational protein modification+++GO:0045773///positive regulation of axon extension+++GO:0008360///regulation of cell shape+++GO:0050900///leukocyte migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0010628///positive regulation of gene expression+++GO:0001932///regulation of protein phosphorylation+++GO:0018149///peptide cross-linking+++GO:0030198///extracellular matrix organization+++GO:0035987///endodermal cell differentiation+++GO:1904237///positive regulation of substrate-dependent cell migration, cell attachment to substrate+++GO:0010952///positive regulation of peptidase activity+++GO:0007160///cell-matrix adhesion+++GO:0042060///wound healing+++GO:2001202///negative regulation of transforming growth factor-beta secretion+++GO:0007044///cell-substrate junction assembly+++GO:0048146///positive regulation of fibroblast proliferation+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:0002576///platelet degranulation","IPR000083///Fibronectin, type I+++IPR013783///Immunoglobulin-like fold+++IPR003961///Fibronectin type III+++IPR036943///Fibronectin type II domain superfamily+++IPR013806///Kringle-like fold+++IPR036116///Fibronectin type III superfamily+++IPR000562///Fibronectin type II domain","[FINC_HUMAN|Reviewed]RecName: Full=Fibronectin; Short=FN; AltName: Full=Cold-insoluble globulin; Short=CIG; Contains: RecName: Full=Anastellin; Contains: RecName: Full=Ugl-Y1; Contains: RecName: Full=Ugl-Y2; Contains: RecName: Full=Ugl-Y3; Flags: Precursor;+++[A0A024R462_HUMAN|Unreviewed]SubName: Full=Fibronectin 1, isoform CRA_n {ECO:0000313|EMBL:EAW70544.1};+++[A6YID2_HUMAN|Unreviewed]SubName: Full=Fibronectin splice variant A {ECO:0000313|EMBL:ABR68534.1}; Flags: Fragment;+++[A6YID3_HUMAN|Unreviewed]SubName: Full=Fibronectin splice variant B {ECO:0000313|EMBL:ABR68535.1}; Flags: Fragment;+++[A6YID4_HUMAN|Unreviewed]SubName: Full=Fibronectin splice variant C {ECO:0000313|EMBL:ABR68536.1}; Flags: Fragment;+++[A6YID5_HUMAN|Unreviewed]SubName: Full=Fibronectin splice variant D {ECO:0000313|EMBL:ABR68537.1}; Flags: Fragment;+++[A6YID6_HUMAN|Unreviewed]SubName: Full=Fibronectin splice variant E {ECO:0000313|EMBL:ABR68538.1}; Flags: Fragment;+++[A6YID7_HUMAN|Unreviewed]SubName: Full=Fibronectin splice variant F {ECO:0000313|EMBL:ABR68539.1}; Flags: Fragment;+++[B7ZLE5_HUMAN|Unreviewed]SubName: Full=FN1 protein {ECO:0000313|EMBL:AAI43755.1};+++[H0Y4K8_HUMAN|Unreviewed]SubName: Full=Fibronectin {ECO:0000313|Ensembl:ENSP00000392565}; Flags: Fragment;+++[H0Y7Z1_HUMAN|Unreviewed]SubName: Full=Fibronectin {ECO:0000313|Ensembl:ENSP00000416139}; Flags: Fragment;+++[O95608_HUMAN|Unreviewed]SubName: Full=Fibronectin {ECO:0000313|EMBL:AAD00013.1}; Flags: Fragment;+++[Q14327_HUMAN|Unreviewed]SubName: Full=FN1 protein {ECO:0000313|EMBL:AAA52464.1}; Flags: Fragment;+++[Q14328_HUMAN|Unreviewed]SubName: Full=FN1 protein {ECO:0000313|EMBL:AAA52466.1}; Flags: Fragment;+++[Q53S27_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein FN1 {ECO:0000313|EMBL:AAY24063.1}; Flags: Fragment;+++[Q6MZF4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686F219 {ECO:0000313|EMBL:CAE45885.1}; SubName: Full=Uncharacterized protein DKFZp686K139 {ECO:0000313|EMBL:CAE46200.1}; Flags: Fragment;+++[Q6MZM7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686O12165 {ECO:0000313|EMBL:CAE46002.1}; Flags: Fragment;+++[Q6N084_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686L11144 {ECO:0000313|EMBL:CAE45786.1}; Flags: Fragment;+++[Q6PJE5_HUMAN|Unreviewed]SubName: Full=FN1 protein {ECO:0000313|EMBL:AAH16875.1}; Flags: Fragment;+++[Q7L553_HUMAN|Unreviewed]SubName: Full=FN1 protein {ECO:0000313|EMBL:AAH05858.2}; Flags: Fragment;+++[Q9UQS6_HUMAN|Unreviewed]SubName: Full=Fibronectin {ECO:0000313|EMBL:AAD10853.1}; Flags: Fragment;"]
[23367,"'LARP1'",2506,3135,2820.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0031931///TORC1 complex+++GO:0005737///cytoplasm+++GO:0005844///polysome+++GO:0010494///cytoplasmic stress granule","GO:0008190///eukaryotic initiation factor 4E binding+++GO:0005515///protein binding+++GO:0000339///RNA cap binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0031369///translation initiation factor binding+++GO:0008494///translation activator activity+++GO:0048027///mRNA 5'-UTR binding+++GO:0045296///cadherin binding+++GO:0003723///RNA binding","GO:0016239///positive regulation of macroautophagy+++GO:0008283///cell proliferation+++GO:0048255///mRNA stabilization+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0031929///TOR signaling+++GO:0038202///TORC1 signaling+++GO:0072752///cellular response to rapamycin+++GO:0045727///positive regulation of translation+++GO:1990928///response to amino acid starvation+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0045070///positive regulation of viral genome replication","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR006607///Protein of unknown function DM15+++IPR006630///La-type HTH domain","[LARP1_HUMAN|Reviewed]RecName: Full=La-related protein 1; AltName: Full=La ribonucleoprotein domain family member 1;+++[A0A0B4J210_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000428589}; Flags: Fragment;+++[E5RH50_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000429904}; Flags: Fragment;+++[E5RHK4_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000429710}; Flags: Fragment;+++[H0YAN4_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000427731}; Flags: Fragment;+++[H0YAX9_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000428251}; Flags: Fragment;+++[H0YBJ5_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000429624}; Flags: Fragment;+++[H0YBM7_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000429852}; Flags: Fragment;+++[H0YBR8_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000430169}; Flags: Fragment;+++[H0YBW1_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000430438}; Flags: Fragment;+++[H0YC33_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000430815}; Flags: Fragment;+++[H0YC73_HUMAN|Unreviewed]SubName: Full=La-related protein 1 {ECO:0000313|Ensembl:ENSP00000431072}; Flags: Fragment;"]
[23386,"'NUDCD3'",1318,1354,1336,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005868///cytoplasmic dynein complex","GO:0051082///unfolded protein binding+++GO:0005515///protein binding","GO:0060271///cilium assembly+++GO:0006457///protein folding+++GO:1905793///protein localization to pericentriolar material+++GO:0032502///developmental process","IPR037905///NudC domain-containing protein 3, p23 domain+++IPR025934///NudC N-terminal domain+++IPR007052///CS domain+++IPR027761///NudC domain-containing protein 3+++IPR037898///NudC family+++IPR008978///HSP20-like chaperone","[NUDC3_HUMAN|Reviewed]RecName: Full=NudC domain-containing protein 3;"]
[23405,"'DICER1'",397,599,498,"05206///MicroRNAs in cancer","H01431///Cushing's syndrome+++H01102///Pituitary adenomas",null,null,"GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0030424///axon+++GO:0033167///ARC complex+++GO:0070578///RISC-loading complex+++GO:0035068///micro-ribonucleoprotein complex+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0030426///growth cone+++GO:0016442///RISC complex+++GO:0030425///dendrite+++GO:0005829///cytosol","GO:0016891///endoribonuclease activity, producing 5'-phosphomonoesters+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003725///double-stranded RNA binding+++GO:0004519///endonuclease activity+++GO:0000166///nucleotide binding+++GO:0004530///deoxyribonuclease I activity+++GO:0004518///nuclease activity+++GO:0004521///endoribonuclease activity+++GO:0019904///protein domain specific binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0004525///ribonuclease III activity+++GO:0070883///pre-miRNA binding+++GO:0035197///siRNA binding+++GO:0046872///metal ion binding+++GO:0003723///RNA binding","GO:0014040///positive regulation of Schwann cell differentiation+++GO:0036404///conversion of ds siRNA to ss siRNA+++GO:0006396///RNA processing+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0035280///miRNA loading onto RISC involved in gene silencing by miRNA+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0038061///NIK/NF-kappaB signaling+++GO:0033168///conversion of ds siRNA to ss siRNA involved in RNA interference+++GO:0031643///positive regulation of myelination+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0021675///nerve development+++GO:0010586///miRNA metabolic process+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0032290///peripheral nervous system myelin formation+++GO:0048812///neuron projection morphogenesis+++GO:0030423///targeting of mRNA for destruction involved in RNA interference+++GO:0031054///pre-miRNA processing+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006309///apoptotic DNA fragmentation+++GO:0030422///production of siRNA involved in RNA interference+++GO:0031047///gene silencing by RNA+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0035087///siRNA loading onto RISC involved in RNA interference","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001650///Helicase, C-terminal+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR038248///Dicer dimerisation domain superfamily+++IPR005034///Dicer dimerisation domain+++IPR014720///Double-stranded RNA-binding domain+++IPR006935///Helicase/UvrB, N-terminal+++IPR036085///PAZ domain superfamily+++IPR003100///PAZ domain+++IPR000999///Ribonuclease III domain+++IPR036389///Ribonuclease III, endonuclease domain superfamily","[DICER_HUMAN|Reviewed]RecName: Full=Endoribonuclease Dicer; EC=3.1.26.3; AltName: Full=Helicase with RNase motif; Short=Helicase MOI;+++[H0YJZ6_HUMAN|Unreviewed]SubName: Full=Endoribonuclease Dicer {ECO:0000313|Ensembl:ENSP00000452556}; Flags: Fragment;+++[Q5D0K5_HUMAN|Unreviewed]SubName: Full=DICER variant 2 {ECO:0000313|EMBL:AAX18334.1}; SubName: Full=DICER variant 3 {ECO:0000313|EMBL:AAX18335.1}; SubName: Full=Endoribonuclease Dicer {ECO:0000313|Ensembl:ENSP00000433060}; Flags: Fragment;"]
[23421,"'ITGB3BP'",45,27,36,"01120///Microbial metabolism in diverse environments+++00521///Streptomycin biosynthesis+++01110///Biosynthesis of secondary metabolites+++00520///Amino sugar and nucleotide sugar metabolism+++00052///Galactose metabolism+++00510///N-Glycan biosynthesis+++00010///Glycolysis / Gluconeogenesis+++00230///Purine metabolism+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++00500///Starch and sucrose metabolism+++00030///Pentose phosphate pathway","H01762///Muscle glycogen storage disease+++H00118///Congenital disorders of glycosylation (CDG) type I+++H01954///Glycogen storage disease type XIV+++H00069///Glycogen storage diseases (GSD)","M00055///N-glycan precursor biosynthesis+++M00549///Nucleotide sugar biosynthesis, glucose => UDP-glucose","R00959///alpha-D-Glucose 1-phosphate 1,6-phosphomutase D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate+++R01057///D-Ribose 1,5-phosphomutase alpha-D-Ribose 1-phosphate <=> D-Ribose 5-phosphate+++R08639///alpha-D-glucose 1,6-phosphomutase D-Glucose 1-phosphate <=> D-Glucose 6-phosphate+++R06262///dolichyl beta-D-glucosyl phosphate:D-Man-alpha-(1->2)-D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->3)-[D-Man-alpha-(1->2)-D-Man-alpha-(1->6)]-D-Man-alpha-(1->6)]-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-1,3-glucosyltransferase Dolichyl D-glucosyl phosphate + G00007 <=> Dolichyl phosphate + G10598","GO:0016020///membrane+++GO:0000777///condensed chromosome kinetochore+++GO:0000775///chromosome, centromeric region+++GO:0005829///cytosol+++GO:0000776///kinetochore+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding","GO:0007049///cell cycle+++GO:0006915///apoptotic process+++GO:0007229///integrin-mediated signaling pathway+++GO:0007165///signal transduction+++GO:0007155///cell adhesion+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043065///positive regulation of apoptotic process+++GO:0051301///cell division","IPR009601///Centromere protein R","[CENPR_HUMAN|Reviewed]RecName: Full=Centromere protein R; Short=CENP-R; AltName: Full=Beta-3-endonexin; AltName: Full=Integrin beta-3-binding protein; AltName: Full=Nuclear receptor-interacting factor 3;+++[D3DQ59_HUMAN|Unreviewed]SubName: Full=Integrin beta 3 binding protein (Beta3-endonexin), isoform CRA_a {ECO:0000313|EMBL:EAX06562.1};"]
[23451,"'SF3B1'",1467,1932,1699.5,"03040///Spliceosome","H01481///Myelodysplastic syndrome (MDS)","M00352///Spliceosome, U2-snRNP",null,"GO:0005634///nucleus+++GO:0034693///U11/U12 snRNP+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0005686///U2 snRNP+++GO:0016607///nuclear speck+++GO:0071004///U2-type prespliceosome+++GO:0005689///U12-type spliceosomal complex+++GO:0005681///spliceosomal complex+++GO:0071005///U2-type precatalytic spliceosome","GO:0005515///protein binding+++GO:0003729///mRNA binding+++GO:0003723///RNA binding","GO:0000375///RNA splicing, via transesterification reactions+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0006397///mRNA processing+++GO:0000245///spliceosomal complex assembly+++GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing","IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical+++IPR015016///Splicing factor 3B subunit 1+++IPR038737///Splicing factor 3B subunit 1-like","[SF3B1_HUMAN|Reviewed]RecName: Full=Splicing factor 3B subunit 1; AltName: Full=Pre-mRNA-splicing factor SF3b 155 kDa subunit; Short=SF3b155; AltName: Full=Spliceosome-associated protein 155; Short=SAP 155;+++[A0JLT9_HUMAN|Unreviewed]SubName: Full=SF3B1 protein {ECO:0000313|EMBL:AAH15530.1}; Flags: Fragment;+++[A0PJH5_HUMAN|Unreviewed]SubName: Full=SF3B1 protein {ECO:0000313|EMBL:AAH29418.1}; Flags: Fragment;+++[B4DGZ4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57368, highly similar to Splicing factor 3B subunit 1 {ECO:0000313|EMBL:BAG57955.1};+++[F8WC19_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 1 {ECO:0000313|Ensembl:ENSP00000392117};+++[H7C341_HUMAN|Unreviewed]SubName: Full=Splicing factor 3B subunit 1 {ECO:0000313|Ensembl:ENSP00000409435}; Flags: Fragment;+++[Q32Q20_HUMAN|Unreviewed]SubName: Full=SF3B1 protein {ECO:0000313|EMBL:AAI07884.1}; Flags: Fragment;+++[Q7Z497_HUMAN|Unreviewed]SubName: Full=SF3B1 protein {ECO:0000313|EMBL:AAH56155.1}; Flags: Fragment;"]
[23475,"'QPRT'",854,653,753.5,"01100///Metabolic pathways+++00760///Nicotinate and nicotinamide metabolism",null,"M00115///NAD biosynthesis, aspartate => NAD","R03348///Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating)   Nicotinate D-ribonucleotide + Diphosphate + CO2 <=> Quinolinate + 5-Phospho-alpha-D-ribose 1-diphosphate","GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0003824///catalytic activity+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0004514///nicotinate-nucleotide diphosphorylase (carboxylating) activity+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0009435///NAD biosynthetic process+++GO:0051259///protein complex oligomerization+++GO:0034213///quinolinate catabolic process+++GO:0019363///pyridine nucleotide biosynthetic process+++GO:0019674///NAD metabolic process","IPR013785///Aldolase-type TIM barrel+++IPR004393///Nicotinate-nucleotide pyrophosphorylase+++IPR027277///Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD+++IPR002638///Quinolinate phosphoribosyl transferase, C-terminal+++IPR022412///Quinolinate phosphoribosyl transferase, N-terminal+++IPR037128///Quinolinate phosphoribosyl transferase, N-terminal domain superfamily+++IPR036068///Nicotinate phosphoribosyltransferase-like, C-terminal","[NADC_HUMAN|Reviewed]RecName: Full=Nicotinate-nucleotide pyrophosphorylase [carboxylating]; EC=2.4.2.19; AltName: Full=Quinolinate phosphoribosyltransferase [decarboxylating]; Short=QAPRTase; Short=QPRTase;+++[B4DDH4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58446, highly similar to Nicotinate-nucleotide pyrophosphorylase (carboxylating) {ECO:0000313|EMBL:BAG56735.1};+++[H3BP73_HUMAN|Unreviewed]SubName: Full=Nicotinate-nucleotide pyrophosphorylase [carboxylating] {ECO:0000313|Ensembl:ENSP00000455183};+++[V9HWJ5_HUMAN|Unreviewed]RecName: Full=Nicotinate-nucleotide pyrophosphorylase [carboxylating] {ECO:0000256|PIRNR:PIRNR006250}; EC=2.4.2.19 {ECO:0000256|PIRNR:PIRNR006250}; AltName: Full=Quinolinate phosphoribosyltransferase [decarboxylating] {ECO:0000256|PIRNR:PIRNR006250};"]
[23503,"'ZFYVE26'",644,908,776,null,"H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005765///lysosomal membrane+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030496///midbody+++GO:0005813///centrosome","GO:0008289///lipid binding+++GO:0046872///metal ion binding+++GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0005515///protein binding","GO:0006281///DNA repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000281///mitotic cytokinesis+++GO:0032465///regulation of cytokinesis+++GO:0007049///cell cycle+++GO:0051301///cell division","IPR028730///Zinc finger FYVE domain-containing protein 26+++IPR017455///Zinc finger, FYVE-related+++IPR000306///FYVE zinc finger+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type","[ZFY26_HUMAN|Reviewed]RecName: Full=Zinc finger FYVE domain-containing protein 26; AltName: Full=FYVE domain-containing centrosomal protein; Short=FYVE-CENT; AltName: Full=Spastizin;+++[A0A2H2FF08_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 26 {ECO:0000313|Ensembl:ENSP00000452142};+++[G3V230_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 26 {ECO:0000313|Ensembl:ENSP00000450431};+++[G3V2D8_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 26 {ECO:0000313|Ensembl:ENSP00000450603};"]
[23518,"'R3HDM1'",715,879,797,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0016020///membrane","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding",null,"IPR001374///R3H domain+++IPR024771///SUZ domain+++IPR036867///R3H domain superfamily","[R3HD1_HUMAN|Reviewed]RecName: Full=R3H domain-containing protein 1;+++[C9JIX1_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000416082}; Flags: Fragment;+++[C9JIX3_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000404098}; Flags: Fragment;+++[H7BZ47_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000387750}; Flags: Fragment;+++[H7C1X4_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000402940}; Flags: Fragment;+++[H7C207_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000403406}; Flags: Fragment;+++[H7C2F9_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405668}; Flags: Fragment;+++[H7C3T7_HUMAN|Unreviewed]SubName: Full=R3H domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000413763}; Flags: Fragment;+++[Q4ZG59_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein R3HDM {ECO:0000313|EMBL:AAX88922.1}; Flags: Fragment;+++[Q53SQ1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein R3HDM {ECO:0000313|EMBL:AAY14728.1}; Flags: Fragment;+++[Q9BVG5_HUMAN|Unreviewed]SubName: Full=R3HDM1 protein {ECO:0000313|EMBL:AAH01217.1};"]
[23539,"'SLC16A8'",1,0,0.5,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015293///symporter activity+++GO:0015129///lactate transmembrane transporter activity+++GO:0008028///monocarboxylic acid transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0015727///lactate transport+++GO:0035873///lactate transmembrane transport+++GO:0050900///leukocyte migration+++GO:0015718///monocarboxylic acid transport+++GO:0006090///pyruvate metabolic process","IPR011701///Major facilitator superfamily+++IPR030759///Monocarboxylate transporter 3+++IPR036259///MFS transporter superfamily+++IPR004743///Monocarboxylate transporter+++IPR020846///Major facilitator superfamily domain","[MOT3_HUMAN|Reviewed]RecName: Full=Monocarboxylate transporter 3; Short=MCT 3; AltName: Full=Solute carrier family 16 member 8;+++[A0A024R1N8_HUMAN|Unreviewed]SubName: Full=Solute carrier 16 (Monocarboxylic acid transporters), member 8, isoform CRA_a {ECO:0000313|EMBL:EAW60215.1};+++[B0QYL4_HUMAN|Unreviewed]SubName: Full=Monocarboxylate transporter 3 {ECO:0000313|Ensembl:ENSP00000409547}; Flags: Fragment;"]
[23555,"'TSPAN15'",278,238,258,{"$nulls":4},"GO:0016020///membrane+++GO:0097197///tetraspanin-enriched microdomain+++GO:0031902///late endosome membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0005788///endoplasmic reticulum lumen","GO:0005515///protein binding+++GO:0019899///enzyme binding","GO:0051604///protein maturation+++GO:0072659///protein localization to plasma membrane+++GO:0008593///regulation of Notch signaling pathway+++GO:0044267///cellular protein metabolic process+++GO:0007166///cell surface receptor signaling pathway","IPR000301///Tetraspanin+++IPR018499///Tetraspanin/Peripherin+++IPR008952///Tetraspanin, EC2 domain superfamily","[TSN15_HUMAN|Reviewed]RecName: Full=Tetraspanin-15; Short=Tspan-15; AltName: Full=Tetraspan NET-7; AltName: Full=Transmembrane 4 superfamily member 15;+++[H7C285_HUMAN|Unreviewed]SubName: Full=Tetraspanin-15 {ECO:0000313|Ensembl:ENSP00000404528}; Flags: Fragment;"]
[23583,"'SMUG1'",177,160,168.5,"03410///Base excision repair",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0017065///single-strand selective uracil DNA N-glycosylase activity+++GO:0004844///uracil DNA N-glycosylase activity+++GO:0000703///oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003677///DNA binding+++GO:0019104///DNA N-glycosylase activity","GO:0006281///DNA repair+++GO:0006284///base-excision repair+++GO:0045008///depyrimidination+++GO:0006974///cellular response to DNA damage stimulus","IPR036895///Uracil-DNA glycosylase-like domain superfamily+++IPR039134///Single-strand selective monofunctional uracil DNA glycosylase","[SMUG1_HUMAN|Reviewed]RecName: Full=Single-strand selective monofunctional uracil DNA glycosylase; EC=3.2.2.-;+++[A0A024RAZ8_HUMAN|Unreviewed]SubName: Full=Single-strand-selective monofunctional uracil-DNA glycosylase 1 isoform 2 {ECO:0000313|EMBL:ALQ34037.1}; SubName: Full=Single-strand-selective monofunctional uracil-DNA glycosylase 1, isoform CRA_a {ECO:0000313|EMBL:EAW96757.1};+++[A0A0S2Z526_HUMAN|Unreviewed]SubName: Full=Single-strand-selective monofunctional uracil-DNA glycosylase 1 isoform 1 {ECO:0000313|EMBL:ALQ34036.1}; Flags: Fragment;+++[A0A0U1RRE6_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000489489};+++[D6RA25_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000423457}; Flags: Fragment;+++[D6RA78_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000423083}; Flags: Fragment;+++[D6RAI1_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000421894};+++[D6RAS0_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000421790}; Flags: Fragment;+++[D6RD88_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000425426}; Flags: Fragment;+++[D6RI04_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000425974};+++[D6RIA4_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000427547}; Flags: Fragment;+++[H0YA95_HUMAN|Unreviewed]SubName: Full=Single-strand selective monofunctional uracil DNA glycosylase {ECO:0000313|Ensembl:ENSP00000426440}; Flags: Fragment;"]
[23594,"'ORC6'",25,18.45,21.725,"04113///Meiosis - yeast+++04110///Cell cycle+++04111///Cell cycle - yeast","H01889///Meier-Gorlin syndrome","M00284///Origin recognition complex",null,"GO:0000808///origin recognition complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005664///nuclear origin of replication recognition complex+++GO:0001650///fibrillar center","GO:0003677///DNA binding+++GO:0003688///DNA replication origin binding+++GO:0005515///protein binding","GO:0051782///negative regulation of cell division+++GO:0006270///DNA replication initiation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006260///DNA replication","IPR020529///Origin recognition complex, subunit 6, metazoa/plant+++IPR008721///Origin recognition complex, subunit 6","[ORC6_HUMAN|Reviewed]RecName: Full=Origin recognition complex subunit 6;+++[A0A024R6R3_HUMAN|Unreviewed]SubName: Full=Origin recognition complex, subunit 6 homolog-like (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW82686.1};+++[H3BMA4_HUMAN|Unreviewed]SubName: Full=Origin recognition complex subunit 6 {ECO:0000313|Ensembl:ENSP00000454299};+++[H3BT22_HUMAN|Unreviewed]SubName: Full=Origin recognition complex subunit 6 {ECO:0000313|Ensembl:ENSP00000456981};+++[H3BTQ7_HUMAN|Unreviewed]SubName: Full=Origin recognition complex subunit 6 {ECO:0000313|Ensembl:ENSP00000457282};"]
[23633,"'KPNA6'",1123.02,1227.69,1175.355,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005643///nuclear pore+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0061608///nuclear import signal receptor activity+++GO:0008139///nuclear localization sequence binding+++GO:0008565///protein transporter activity","GO:0060135///maternal process involved in female pregnancy+++GO:0019054///modulation by virus of host process+++GO:0015031///protein transport+++GO:0006607///NLS-bearing protein import into nucleus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006606///protein import into nucleus","IPR024931///Importin subunit alpha+++IPR016024///Armadillo-type fold+++IPR000225///Armadillo+++IPR011989///Armadillo-like helical+++IPR036975///Importin-alpha, importin-beta-binding domain superfamily+++IPR002652///Importin-alpha, importin-beta-binding domain+++IPR032413///Atypical Arm repeat","[IMA7_HUMAN|Reviewed]RecName: Full=Importin subunit alpha-7; AltName: Full=Karyopherin subunit alpha-6;+++[G1UI19_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-7 {ECO:0000313|EMBL:BAK64142.1}; Flags: Fragment;+++[L8E7Z7_HUMAN|Unreviewed]SubName: Full=Alternative protein KPNA6 {ECO:0000313|EMBL:CCQ43410.1};+++[Q5TFJ7_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-7 {ECO:0000313|Ensembl:ENSP00000415677}; Flags: Fragment;+++[S4R3E5_HUMAN|Unreviewed]SubName: Full=Importin subunit alpha-7 {ECO:0000313|Ensembl:ENSP00000474234};"]
[23657,"'SLC7A11'",168,249,208.5,"04216///Ferroptosis",{"$nulls":3},"GO:0016020///membrane+++GO:0097449///astrocyte projection+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005791///rough endoplasmic reticulum+++GO:0005856///cytoskeleton+++GO:0031526///brush border membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0009986///cell surface","GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015327///cystine:glutamate antiporter activity","GO:0034599///cellular response to oxidative stress+++GO:0021756///striatum development+++GO:2000211///regulation of glutamate metabolic process+++GO:0034775///glutathione transmembrane transport+++GO:0014070///response to organic cyclic compound+++GO:0060173///limb development+++GO:0006979///response to oxidative stress+++GO:1904717///regulation of AMPA glutamate receptor clustering+++GO:0070527///platelet aggregation+++GO:0033029///regulation of neutrophil apoptotic process+++GO:0051223///regulation of protein transport+++GO:0007420///brain development+++GO:0070306///lens fiber cell differentiation+++GO:0009636///response to toxic substance+++GO:0042127///regulation of cell proliferation+++GO:0090461///glutamate homeostasis+++GO:0140206///dipeptide import across plasma membrane+++GO:0071702///organic substance transport+++GO:0006865///amino acid transport+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0030534///adult behavior+++GO:0050804///modulation of chemical synaptic transmission+++GO:1901494///regulation of cysteine metabolic process+++GO:0048286///lung alveolus development+++GO:0051775///response to redox state+++GO:1903786///regulation of glutathione biosynthetic process+++GO:0048021///regulation of melanin biosynthetic process+++GO:1900407///regulation of cellular response to oxidative stress+++GO:0050807///regulation of synapse organization+++GO:0055085///transmembrane transport+++GO:0008542///visual learning+++GO:0050900///leukocyte migration+++GO:0021591///ventricular system development+++GO:0035094///response to nicotine+++GO:0006749///glutathione metabolic process+++GO:0098712///L-glutamate import across plasma membrane","IPR004760///L-type amino acid transporter+++IPR002293///Amino acid/polyamine transporter I","[XCT_HUMAN|Reviewed]RecName: Full=Cystine/glutamate transporter; AltName: Full=Amino acid transport system xc-; AltName: Full=Calcium channel blocker resistance protein CCBR1; AltName: Full=Solute carrier family 7 member 11; AltName: Full=xCT;+++[H0Y9F9_HUMAN|Unreviewed]SubName: Full=Cystine/glutamate transporter {ECO:0000313|Ensembl:ENSP00000424046}; Flags: Fragment;+++[Q4W5A5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SLC7A11 {ECO:0000313|EMBL:AAY41053.1}; Flags: Fragment;+++[Q9P1X0_HUMAN|Unreviewed]SubName: Full=Cystine/glutamate transporter {ECO:0000313|EMBL:BAA94999.1}; Flags: Fragment;"]
[23710,"'GABARAPL1'",722,727,724.5,"05167///Kaposi's sarcoma-associated herpesvirus infection+++04137///Mitophagy - animal+++04068///FoxO signaling pathway+++04212///Longevity regulating pathway - worm+++04139///Mitophagy - yeast+++04727///GABAergic synapse+++04140///Autophagy - animal+++04138///Autophagy - yeast+++04371///Apelin signaling pathway+++04621///NOD-like receptor signaling pathway+++04136///Autophagy - other",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005856///cytoskeleton+++GO:0032590///dendrite membrane+++GO:0044297///cell body+++GO:0005776///autophagosome+++GO:0000421///autophagosome membrane+++GO:0005874///microtubule+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0032839///dendrite cytoplasm+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005622///intracellular","GO:0048487///beta-tubulin binding+++GO:0050811///GABA receptor binding+++GO:0030957///Tat protein binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0000422///autophagy of mitochondrion+++GO:0006995///cellular response to nitrogen starvation+++GO:0097352///autophagosome maturation+++GO:0000045///autophagosome assembly+++GO:0006914///autophagy+++GO:0016236///macroautophagy","IPR004241///Autophagy protein Atg8 ubiquitin-like+++IPR029071///Ubiquitin-like domain superfamily","[GBRL1_HUMAN|Reviewed]RecName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1; AltName: Full=Early estrogen-regulated protein; AltName: Full=GABA(A) receptor-associated protein-like 1; AltName: Full=Glandular epithelial cell protein 1; Short=GEC-1; Flags: Precursor;+++[A0A024RAP5_HUMAN|Unreviewed]SubName: Full=GABA(A) receptor-associated protein like 1, isoform CRA_a {ECO:0000313|EMBL:EAW96168.1};+++[A0A0G2JKT8_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000437451}; Flags: Fragment;+++[F5GX12_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000441165};+++[F5GYD9_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000446456};+++[F5GZY7_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000444108}; Flags: Fragment;+++[F5H007_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000444055};+++[G3V1T7_HUMAN|Unreviewed]SubName: Full=GABA(A) receptor-associated protein like 1, isoform CRA_e {ECO:0000313|EMBL:EAW96169.1}; SubName: Full=Gamma-aminobutyric acid receptor-associated protein-like 1 {ECO:0000313|Ensembl:ENSP00000445709};"]
[23769,"'FLRT1'",0,1.02,0.51,null,"H00255///Hypogonadotropic hypogonadism",null,null,"GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0032809///neuronal cell body membrane+++GO:0005887///integral component of plasma membrane+++GO:0044306///neuron projection terminus+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005789///endoplasmic reticulum membrane+++GO:0042995///cell projection+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005783///endoplasmic reticulum+++GO:0005925///focal adhesion+++GO:0005911///cell-cell junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane","GO:0030674///protein binding, bridging+++GO:0005104///fibroblast growth factor receptor binding","GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0007275///multicellular organism development+++GO:0016358///dendrite development+++GO:0007155///cell adhesion+++GO:0051965///positive regulation of synapse assembly+++GO:1990138///neuron projection extension","IPR001611///Leucine-rich repeat+++IPR000372///Leucine-rich repeat N-terminal domain+++IPR036116///Fibronectin type III superfamily+++IPR003961///Fibronectin type III+++IPR003591///Leucine-rich repeat, typical subtype+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR032675///Leucine-rich repeat domain superfamily+++IPR013783///Immunoglobulin-like fold","[FLRT1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat transmembrane protein FLRT1; AltName: Full=Fibronectin-like domain-containing leucine-rich transmembrane protein 1; Flags: Precursor;"]
[24138,"'IFIT5'",302,334,318,"05168///Herpes simplex infection+++05160///Hepatitis C",{"$nulls":3},"GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0032587///ruffle membrane+++GO:0008385///IkappaB kinase complex+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0045177///apical part of cell+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003727///single-stranded RNA binding+++GO:0003690///double-stranded DNA binding+++GO:0008266///poly(U) RNA binding+++GO:0000339///RNA cap binding+++GO:0000049///tRNA binding","GO:0051607///defense response to virus+++GO:0045071///negative regulation of viral genome replication+++GO:0045087///innate immune response+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0002376///immune system process","IPR013026///Tetratricopeptide repeat-containing domain+++IPR024125///Interferon-induced protein with tetratricopeptide repeat 5+++IPR019734///Tetratricopeptide repeat+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013105///Tetratricopeptide repeat 2","[IFIT5_HUMAN|Reviewed]RecName: Full=Interferon-induced protein with tetratricopeptide repeats 5; Short=IFIT-5; AltName: Full=Interferon-induced 58 kDa protein; AltName: Full=Retinoic acid- and interferon-inducible 58 kDa protein; Short=P58;"]
[245812,"'CNPY4'",305,282,293.5,{"$nulls":4},"GO:0005576///extracellular region","GO:0005102///signaling receptor binding+++GO:0003674///molecular_function","GO:1903078///positive regulation of protein localization to plasma membrane","IPR021852///Domain of unknown function DUF3456","[CNPY4_HUMAN|Reviewed]RecName: Full=Protein canopy homolog 4; Flags: Precursor;+++[A0A0J9YXE1_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 4 {ECO:0000313|Ensembl:ENSP00000488362}; Flags: Fragment;+++[A0A0J9YYJ0_HUMAN|Unreviewed]SubName: Full=Protein canopy homolog 4 {ECO:0000313|Ensembl:ENSP00000488873}; Flags: Fragment;"]
[2487,"'FRZB'",3,15,9,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0017147///Wnt-protein binding","GO:0061053///somite development+++GO:0001501///skeletal system development+++GO:0016055///Wnt signaling pathway+++GO:0043065///positive regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0035567///non-canonical Wnt signaling pathway+++GO:0030308///negative regulation of cell growth+++GO:0070367///negative regulation of hepatocyte differentiation+++GO:0030154///cell differentiation+++GO:0014033///neural crest cell differentiation+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0090103///cochlea morphogenesis+++GO:0010721///negative regulation of cell development+++GO:0042472///inner ear morphogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0060029///convergent extension involved in organogenesis+++GO:0060070///canonical Wnt signaling pathway+++GO:0045600///positive regulation of fat cell differentiation+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0061037///negative regulation of cartilage development","IPR015526///Frizzled/secreted frizzled-related protein+++IPR036790///Frizzled cysteine-rich domain superfamily+++IPR018933///Netrin module, non-TIMP type+++IPR008993///Tissue inhibitor of metalloproteinases-like, OB-fold+++IPR026556///Secreted frizzled-related protein 3+++IPR001134///Netrin domain+++IPR020067///Frizzled domain+++IPR035813///Secreted frizzled-related protein 3, NTR domain","[SFRP3_HUMAN|Reviewed]RecName: Full=Secreted frizzled-related protein 3; Short=sFRP-3; AltName: Full=Frezzled; AltName: Full=Fritz; AltName: Full=Frizzled-related protein 1; AltName: Full=FrzB-1; Flags: Precursor;+++[D9ZGF6_HUMAN|Unreviewed]SubName: Full=Frizzled-related protein {ECO:0000313|EMBL:ADL14515.1};+++[Q53QN4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein FRZB {ECO:0000313|EMBL:AAX93117.1}; Flags: Fragment;+++[Q53QT6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein FRZB {ECO:0000313|EMBL:AAY24241.1}; Flags: Fragment;"]
[2527,"'FUT5'",3,0,1.5,"00601///Glycosphingolipid biosynthesis - lacto and neolacto series+++01100///Metabolic pathways",null,null,"R06025///GDP-L-fucose + Paragloboside <=> GDP + III3Fuc-nLc4Cer+++R06039///GDP-L-fucose + nLc8Cer <=> GDP + G00084+++R06227///GDP-L-fucose + G00081 <=> GDP + G00082+++R06230///GDP-L-fucose + nLc6Cer <=> GDP + III3Fuc-nLc6Cer+++R06038///GDP-L-fucose + nLc6Cer <=> GDP + V3Fuc-nLc6Cer+++R06076///GDP-L-fucose + VI2Fuc-nLc6 <=> GDP + G00081+++R06075///GDP-L-fucose + Sialyl-3-paragloboside <=> GDP + IV3NeuAc,III3Fuc-nLc4Cer+++R06095///GDP-L-fucose + IV2Fuc-nLc4Cer <=> GDP + III3,IV2Fuc-nLc4Cer+++R06222///GDP-L-fucose + G00084 <=> GDP + G00085+++R06224///GDP-L-fucose + G00085 <=> GDP + G00086+++R06221///GDP-L-fucose + V3Fuc-nLc6Cer <=> GDP + V3Fuc,III3Fuc-nLc6Cer","GO:0032580///Golgi cisterna membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0017060///3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008417///fucosyltransferase activity+++GO:0046920///alpha-(1->3)-fucosyltransferase activity","GO:0006486///protein glycosylation+++GO:0005975///carbohydrate metabolic process+++GO:0006672///ceramide metabolic process+++GO:0036065///fucosylation+++GO:0042355///L-fucose catabolic process","IPR001503///Glycosyl transferase family 10+++IPR038577///GT10-like superfamily+++IPR031481///Fucosyltransferase, N-terminal","[FUT5_HUMAN|Reviewed]RecName: Full=Alpha-(1,3)-fucosyltransferase 5; EC=2.4.1.65; AltName: Full=Fucosyltransferase 5; AltName: Full=Fucosyltransferase V; Short=Fuc-TV; Short=FucT-V; AltName: Full=Galactoside 3-L-fucosyltransferase;+++[K7ENC0_HUMAN|Unreviewed]SubName: Full=Alpha-(1,3)-fucosyltransferase 5 {ECO:0000313|Ensembl:ENSP00000466880};"]
[253260,"'RICTOR'",174,266,220,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0031932///TORC2 complex+++GO:0005829///cytosol","GO:0008047///enzyme activator activity+++GO:0019901///protein kinase binding+++GO:0043022///ribosome binding+++GO:0005515///protein binding","GO:0030010///establishment of cell polarity+++GO:0031929///TOR signaling+++GO:0032008///positive regulation of TOR signaling+++GO:0031532///actin cytoskeleton reorganization+++GO:0042325///regulation of phosphorylation+++GO:0016032///viral process+++GO:0030950///establishment or maintenance of actin cytoskeleton polarity+++GO:0033135///regulation of peptidyl-serine phosphorylation+++GO:0030838///positive regulation of actin filament polymerization+++GO:0001932///regulation of protein phosphorylation+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0007275///multicellular organism development+++GO:0051896///regulation of protein kinase B signaling+++GO:0032148///activation of protein kinase B activity+++GO:0018105///peptidyl-serine phosphorylation+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0032956///regulation of actin cytoskeleton organization+++GO:2000114///regulation of establishment of cell polarity+++GO:0050727///regulation of inflammatory response+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0010468///regulation of gene expression+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0043087///regulation of GTPase activity","IPR029259///Rapamycin-insensitive companion of mTOR, phosphorylation-site+++IPR029451///Rapamycin-insensitive companion of mTOR, middle domain+++IPR016024///Armadillo-type fold+++IPR028267///Rapamycin-insensitive companion of mTOR, N-terminal domain+++IPR028268///Pianissimo family+++IPR029453///Rapamycin-insensitive companion of mTOR, domain 4+++IPR029452///Rapamycin-insensitive companion of mTOR, domain 5","[RICTR_HUMAN|Reviewed]RecName: Full=Rapamycin-insensitive companion of mTOR; AltName: Full=AVO3 homolog; Short=hAVO3;+++[D6R9S6_HUMAN|Unreviewed]SubName: Full=Rapamycin-insensitive companion of mTOR {ECO:0000313|Ensembl:ENSP00000423162}; Flags: Fragment;+++[Q8N6M7_HUMAN|Unreviewed]SubName: Full=RICTOR protein {ECO:0000313|EMBL:AAH29608.1};"]
[253769,"'WDR27'",62,72,67,"04140///Autophagy - animal+++04137///Mitophagy - animal+++05225///Hepatocellular carcinoma",{"$nulls":3},"GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0007399///nervous system development+++GO:0006351///transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043312///neutrophil degranulation+++GO:0032197///transposition, RNA-mediated","IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR001680///WD40 repeat+++IPR036322///WD40-repeat-containing domain superfamily+++IPR011047///Quinoprotein alcohol dehydrogenase-like superfamily+++IPR017986///WD40-repeat-containing domain","[WDR27_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 27;+++[F8VUY7_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 27 {ECO:0000313|Ensembl:ENSP00000449696}; Flags: Fragment;+++[H7C3H5_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 27 {ECO:0000313|Ensembl:ENSP00000411915}; Flags: Fragment;"]
[254122,"'SNX32'",77,54,65.5,"04144///Endocytosis",{"$nulls":3},"GO:0005768///endosome+++GO:0019898///extrinsic component of membrane","GO:0005515///protein binding+++GO:0035091///phosphatidylinositol binding","GO:0015031///protein transport+++GO:0016241///regulation of macroautophagy","IPR027267///AH/BAR domain superfamily+++IPR014637///Sorting nexin-5/6/32+++IPR015404///Sorting nexin Vps5-like, C-terminal+++IPR036871///PX domain superfamily+++IPR001683///Phox homologous domain+++IPR039358///Sorting nexin-like","[SNX32_HUMAN|Reviewed]RecName: Full=Sorting nexin-32; AltName: Full=Sorting nexin-6B;"]
[2547,"'XRCC6'",2716,2311,2513.5,"03450///Non-homologous end-joining",null,"M00297///DNA-PK complex",null,"GO:1904813///ficolin-1-rich granule lumen+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0043564///Ku70:Ku80 complex+++GO:0032993///protein-DNA complex+++GO:0005829///cytosol+++GO:0070419///nonhomologous end joining complex+++GO:0034774///secretory granule lumen+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0032991///protein-containing complex+++GO:0005576///extracellular region+++GO:0000783///nuclear telomere cap complex+++GO:0005737///cytoplasm","GO:0008022///protein C-terminus binding+++GO:0003824///catalytic activity+++GO:0003684///damaged DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005524///ATP binding+++GO:0030332///cyclin binding+++GO:0003691///double-stranded telomeric DNA binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0042162///telomeric DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0016829///lyase activity+++GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0044877///protein-containing complex binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity","GO:0045860///positive regulation of protein kinase activity+++GO:0006266///DNA ligation+++GO:0071475///cellular hyperosmotic salinity response+++GO:0008152///metabolic process+++GO:0051290///protein heterotetramerization+++GO:0045087///innate immune response+++GO:0097680///double-strand break repair via classical nonhomologous end joining+++GO:0071481///cellular response to X-ray+++GO:0006281///DNA repair+++GO:0007420///brain development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048660///regulation of smooth muscle cell proliferation+++GO:0043312///neutrophil degranulation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0032481///positive regulation of type I interferon production+++GO:0000723///telomere maintenance+++GO:0002376///immune system process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0075713///establishment of integrated proviral latency+++GO:0071480///cellular response to gamma radiation+++GO:0032508///DNA duplex unwinding+++GO:0006310///DNA recombination+++GO:0002218///activation of innate immune response","IPR027388///Ku70, bridge and pillars domain superfamily+++IPR006164///Ku70/Ku80 beta-barrel domain+++IPR006165///Ku70+++IPR005161///Ku70/Ku80, N-terminal alpha/beta+++IPR003034///SAP domain+++IPR036465///von Willebrand factor A-like domain superfamily+++IPR016194///SPOC-like, C-terminal domain superfamily+++IPR036361///SAP domain superfamily+++IPR005160///Ku70/Ku80 C-terminal arm","[XRCC6_HUMAN|Reviewed]RecName: Full=X-ray repair cross-complementing protein 6; EC=3.6.4.-; EC=4.2.99.-; AltName: Full=5'-deoxyribose-5-phosphate lyase Ku70; Short=5'-dRP lyase Ku70; AltName: Full=70 kDa subunit of Ku antigen; AltName: Full=ATP-dependent DNA helicase 2 subunit 1; AltName: Full=ATP-dependent DNA helicase II 70 kDa subunit; AltName: Full=CTC box-binding factor 75 kDa subunit; Short=CTC75; Short=CTCBF; AltName: Full=DNA repair protein XRCC6; AltName: Full=Lupus Ku autoantigen protein p70; Short=Ku70; AltName: Full=Thyroid-lupus autoantigen; Short=TLAA; AltName: Full=X-ray repair complementing defective repair in Chinese hamster cells 6;+++[A0A024R1N4_HUMAN|Unreviewed]SubName: Full=X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa), isoform CRA_a {ECO:0000313|EMBL:EAW60447.1};+++[B1AHC9_HUMAN|Unreviewed]SubName: Full=X-ray repair cross-complementing protein 6 {ECO:0000313|Ensembl:ENSP00000384082};+++[B4DE32_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53970, highly similar to ATP-dependent DNA helicase 2 subunit 1 (EC3.6.1.-) {ECO:0000313|EMBL:BAG56943.1};+++[B4E356_HUMAN|Unreviewed]SubName: Full=cDNA FLJ54993, highly similar to ATP-dependent DNA helicase 2 subunit 1 {ECO:0000313|EMBL:BAG65368.1};+++[Q6IC76_HUMAN|Unreviewed]SubName: Full=G22P1 protein {ECO:0000313|EMBL:CAG30378.1};"]
[255101,"'CFAP65'",19,3,11,{"$nulls":4},"GO:0016020///membrane+++GO:0005929///cilium+++GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0031514///motile cilium+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0003723///RNA binding",null,"IPR008962///PapD-like superfamily+++IPR013783///Immunoglobulin-like fold+++IPR000535///Major sperm protein (MSP) domain+++IPR031549///Abnormal spindle-like microcephaly-associated protein, ASH domain","[CFA65_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 65 {ECO:0000305}; AltName: Full=Coiled-coil domain-containing protein 108 {ECO:0000312|HGNC:HGNC:25325};+++[B4DYZ8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58438 {ECO:0000313|EMBL:BAG63910.1};+++[B4DZ05_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58439 {ECO:0000313|EMBL:BAG63917.1};+++[C9JIV0_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 65 {ECO:0000313|Ensembl:ENSP00000396836}; Flags: Fragment;+++[C9JLP9_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 65 {ECO:0000313|Ensembl:ENSP00000413746}; Flags: Fragment;+++[C9JVA0_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 65 {ECO:0000313|Ensembl:ENSP00000393483}; Flags: Fragment;+++[H7C0B4_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 65 {ECO:0000313|Ensembl:ENSP00000394019}; Flags: Fragment;+++[Q49A14_HUMAN|Unreviewed]SubName: Full=CCDC108 protein {ECO:0000313|EMBL:AAH47637.1}; SubName: Full=Cilia- and flagella-associated protein 65 {ECO:0000313|Ensembl:ENSP00000413377};"]
[255520,"'ELMOD2'",492.42,536.73,514.575,{"$nulls":4},"GO:0016020///membrane","GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0051607///defense response to virus+++GO:0050688///regulation of defense response to virus","IPR030724///ELMO domain-containing protein 2+++IPR006816///ELMO domain","[ELMD2_HUMAN|Reviewed]RecName: Full=ELMO domain-containing protein 2;+++[D6RBS5_HUMAN|Unreviewed]SubName: Full=ELMO domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000422582}; Flags: Fragment;+++[D6RHX2_HUMAN|Unreviewed]SubName: Full=ELMO domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000427592}; Flags: Fragment;+++[D6RJB5_HUMAN|Unreviewed]SubName: Full=ELMO domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000427265}; Flags: Fragment;+++[V9GY58_HUMAN|Unreviewed]SubName: Full=ELMO domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000476419};"]
[2561,"'GABRB2'",2,5,3.5,"04727///GABAergic synapse+++04723///Retrograde endocannabinoid signaling+++05033///Nicotine addiction+++04080///Neuroactive ligand-receptor interaction+++05032///Morphine addiction+++04726///Serotonergic synapse","H01813///Lennox-Gastaut syndrome+++H02150///Infantile or early childhood epileptic encephalopathy+++H00606///Early infantile epileptic encephalopathy+++H00808///Idiopathic generalized epilepsies (IGEs)",null,null,"GO:0045202///synapse+++GO:0005829///cytosol+++GO:1902711///GABA-A receptor complex+++GO:0043005///neuron projection+++GO:1902710///GABA receptor complex+++GO:0098982///GABA-ergic synapse+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0070062///extracellular exosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0045211///postsynaptic membrane+++GO:0031410///cytoplasmic vesicle+++GO:0034707///chloride channel complex+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0004890///GABA-A receptor activity+++GO:0005254///chloride channel activity+++GO:0005216///ion channel activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005230///extracellular ligand-gated ion channel activity+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential+++GO:0005237///inhibitory extracellular ligand-gated ion channel activity+++GO:0016917///GABA receptor activity","GO:1901215///negative regulation of neuron death+++GO:0034220///ion transmembrane transport+++GO:0050877///nervous system process+++GO:0048666///neuron development+++GO:0060119///inner ear receptor cell development+++GO:1902476///chloride transmembrane transport+++GO:0043523///regulation of neuron apoptotic process+++GO:0051932///synaptic transmission, GABAergic+++GO:0007605///sensory perception of sound+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0007165///signal transduction+++GO:0006811///ion transport+++GO:0006821///chloride transport+++GO:0042391///regulation of membrane potential+++GO:0071420///cellular response to histamine+++GO:0007268///chemical synaptic transmission+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0060384///innervation+++GO:0007214///gamma-aminobutyric acid signaling pathway+++GO:0090102///cochlea development","IPR036734///Neurotransmitter-gated ion-channel ligand-binding domain superfamily+++IPR002289///Gamma-aminobutyric-acid A receptor, beta subunit+++IPR036719///Neurotransmitter-gated ion-channel transmembrane domain superfamily+++IPR006201///Neurotransmitter-gated ion-channel+++IPR006202///Neurotransmitter-gated ion-channel ligand-binding domain+++IPR006028///Gamma-aminobutyric acid A receptor/Glycine receptor alpha+++IPR018000///Neurotransmitter-gated ion-channel, conserved site+++IPR006029///Neurotransmitter-gated ion-channel transmembrane domain","[GBRB2_HUMAN|Reviewed]RecName: Full=Gamma-aminobutyric acid receptor subunit beta-2; AltName: Full=GABA(A) receptor subunit beta-2; Flags: Precursor;+++[B7Z279_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit beta-2 {ECO:0000313|Ensembl:ENSP00000429750}; SubName: Full=cDNA FLJ53759, highly similar to Gamma-aminobutyric-acid receptor subunit beta-2 {ECO:0000313|EMBL:BAH11765.1};+++[D1M715_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid A receptor beta 2 {ECO:0000313|EMBL:ACY71653.1}; Flags: Fragment;+++[D1M744_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid A receptor beta 2 {ECO:0000313|EMBL:ACY71682.1}; Flags: Fragment;+++[E7EV50_HUMAN|Unreviewed]SubName: Full=Gamma-aminobutyric acid receptor subunit beta-2 {ECO:0000313|Ensembl:ENSP00000430532};"]
[256536,"'TCERG1L'",11,3,7,{"$nulls":4},"GO:0005634///nucleus","GO:0070063///RNA polymerase binding",null,"IPR036517///FF domain superfamily+++IPR001202///WW domain+++IPR002713///FF domain+++IPR036020///WW domain superfamily","[TCRGL_HUMAN|Reviewed]RecName: Full=Transcription elongation regulator 1-like protein;"]
[257106,"'ARHGAP30'",0,1,0.5,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle","GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007264///small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity","IPR000198///Rho GTPase-activating protein domain+++IPR008936///Rho GTPase activation protein","[RHG30_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 30; AltName: Full=Rho-type GTPase-activating protein 30;+++[A0A0A0MRJ8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 30 {ECO:0000313|Ensembl:ENSP00000356994};+++[A0A0A0MRJ9_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 30 {ECO:0000313|Ensembl:ENSP00000356995};+++[E9PAN4_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 30 {ECO:0000313|Ensembl:ENSP00000356997};+++[E9PLA4_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 30 {ECO:0000313|Ensembl:ENSP00000431387};+++[E9PLT5_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 30 {ECO:0000313|Ensembl:ENSP00000431291};+++[L0R4U0_HUMAN|Unreviewed]SubName: Full=Alternative protein ARHGAP30 {ECO:0000313|EMBL:CCO13678.1};"]
[25764,"'HYPK'",745,486,615.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0015630///microtubule cytoskeleton+++GO:0005654///nucleoplasm","GO:0047485///protein N-terminus binding+++GO:0005515///protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0050821///protein stabilization","IPR038922///Huntingtin-interacting protein K, UBA-like domain","[HYPK_HUMAN|Reviewed]RecName: Full=Huntingtin-interacting protein K; AltName: Full=Huntingtin yeast partner K;+++[A0A024R5Q1_HUMAN|Unreviewed]SubName: Full=HCG2003792, isoform CRA_b {ECO:0000313|EMBL:EAW77242.1};+++[J3QT56_HUMAN|Unreviewed]SubName: Full=Huntingtin-interacting protein K {ECO:0000313|Ensembl:ENSP00000394060};"]
[25793,"'FBXO7'",1492,1556,1524,null,"H00057///Parkinson's disease (PD)",null,null,"GO:0097409///glial cytoplasmic inclusion+++GO:1990037///Lewy body core+++GO:0019005///SCF ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0097462///Lewy neurite+++GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:1990038///Lewy body corona+++GO:0097414///classical Lewy body","GO:0004842///ubiquitin-protein transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0046982///protein heterodimerization activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0043130///ubiquitin binding","GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0045620///negative regulation of lymphocyte differentiation+++GO:0000422///autophagy of mitochondrion+++GO:1901215///negative regulation of neuron death+++GO:0040012///regulation of locomotion+++GO:1903204///negative regulation of oxidative stress-induced neuron death+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0006626///protein targeting to mitochondrion+++GO:1903208///negative regulation of hydrogen peroxide-induced neuron death+++GO:0016567///protein ubiquitination+++GO:0010975///regulation of neuron projection development+++GO:0043687///post-translational protein modification+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0000209///protein polyubiquitination+++GO:0031647///regulation of protein stability","IPR036047///F-box-like domain superfamily+++IPR029071///Ubiquitin-like domain superfamily+++IPR021625///PI31 proteasome regulator,  N-terminal+++IPR001810///F-box domain","[FBX7_HUMAN|Reviewed]RecName: Full=F-box only protein 7;+++[A2A282_HUMAN|Unreviewed]SubName: Full=F-box only protein 7 {ECO:0000313|Ensembl:ENSP00000404388}; Flags: Fragment;+++[F8WBR0_HUMAN|Unreviewed]SubName: Full=F-box only protein 7 {ECO:0000313|Ensembl:ENSP00000406155};+++[F8WDR9_HUMAN|Unreviewed]SubName: Full=F-box only protein 7 {ECO:0000313|Ensembl:ENSP00000395823};"]
[25807,"'RHBDD3'",487.82,457.15,472.485,"04137///Mitophagy - animal+++05202///Transcriptional misregulation in cancer+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004252///serine-type endopeptidase activity","GO:0032815///negative regulation of natural killer cell activation+++GO:0001889///liver development+++GO:0050708///regulation of protein secretion+++GO:0006508///proteolysis+++GO:0002673///regulation of acute inflammatory response+++GO:0045732///positive regulation of protein catabolic process+++GO:0000165///MAPK cascade+++GO:0009410///response to xenobiotic stimulus","IPR022764///Peptidase S54, rhomboid domain+++IPR009060///UBA-like superfamily+++IPR035952///Rhomboid-like superfamily+++IPR015940///Ubiquitin-associated domain","[RHBD3_HUMAN|Reviewed]RecName: Full=Rhomboid domain-containing protein 3;+++[A0A024R1J2_HUMAN|Unreviewed]SubName: Full=Rhomboid domain containing 3, isoform CRA_a {ECO:0000313|EMBL:EAW59779.1};+++[B0QYJ1_HUMAN|Unreviewed]SubName: Full=Rhomboid domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000413128}; Flags: Fragment;+++[B0QYJ2_HUMAN|Unreviewed]SubName: Full=Rhomboid domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000384113}; Flags: Fragment;+++[F8WFA9_HUMAN|Unreviewed]SubName: Full=Rhomboid domain-containing protein 3 {ECO:0000313|Ensembl:ENSP00000399550};"]
[25827,"'FBXL2'",412,395.65,403.825,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00604///Deafness, autosomal dominant+++H01927///Van der Woude syndrome",null,null,"GO:0019005///SCF ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0036312///phosphatidylinositol 3-kinase regulatory subunit binding+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0019903///protein phosphatase binding+++GO:0005516///calmodulin binding","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016032///viral process+++GO:0006508///proteolysis+++GO:0006464///cellular protein modification process+++GO:0010506///regulation of autophagy+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0006513///protein monoubiquitination+++GO:0016567///protein ubiquitination","IPR001810///F-box domain+++IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily+++IPR006553///Leucine-rich repeat, cysteine-containing subtype","[FBXL2_HUMAN|Reviewed]RecName: Full=F-box/LRR-repeat protein 2 {ECO:0000305}; AltName: Full=F-box and leucine-rich repeat protein 2 {ECO:0000312|HGNC:HGNC:13598}; AltName: Full=F-box protein FBL2/FBL3 {ECO:0000303|PubMed:10945468, ECO:0000312|EMBL:AAF04510.1};+++[F8WB01_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 2 {ECO:0000313|Ensembl:ENSP00000405084};+++[F8WBS9_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 2 {ECO:0000313|Ensembl:ENSP00000411484};+++[F8WBW7_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 2 {ECO:0000313|Ensembl:ENSP00000411273};+++[F8WC58_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 2 {ECO:0000313|Ensembl:ENSP00000406737};+++[F8WCQ8_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 2 {ECO:0000313|Ensembl:ENSP00000416332};+++[F8WE99_HUMAN|Unreviewed]SubName: Full=F-box/LRR-repeat protein 2 {ECO:0000313|Ensembl:ENSP00000408895};"]
[25843,"'MOB4'",261,237,249,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding",null,"IPR036703///MOB kinase activator superfamily+++IPR005301///MOB kinase activator family","[PHOCN_HUMAN|Reviewed]RecName: Full=MOB-like protein phocein; AltName: Full=2C4D; AltName: Full=Class II mMOB1; AltName: Full=Mob1 homolog 3; Short=Mob3; AltName: Full=Mps one binder kinase activator-like 3; AltName: Full=Preimplantation protein 3;+++[A0A024R3X9_HUMAN|Unreviewed]SubName: Full=Preimplantation protein 3, isoform CRA_a {ECO:0000313|EMBL:EAW70168.1};+++[B4DM50_HUMAN|Unreviewed]SubName: Full=MOB-like protein phocein {ECO:0000313|Ensembl:ENSP00000387240}; SubName: Full=cDNA FLJ52887, highly similar to Preimplantation protein 3 {ECO:0000313|EMBL:BAG59762.1};+++[F8W8B0_HUMAN|Unreviewed]SubName: Full=MOB-like protein phocein {ECO:0000313|Ensembl:ENSP00000387043};+++[F8WAQ8_HUMAN|Unreviewed]SubName: Full=MOB-like protein phocein {ECO:0000313|Ensembl:ENSP00000397052};"]
[25844,"'YIPF3'",6810,5687,6248.5,"02010///ABC transporters",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle","GO:0005515///protein binding","GO:0030154///cell differentiation","IPR006977///Yip1 domain+++IPR026637///YIP1 family member 3","[YIPF3_HUMAN|Reviewed]RecName: Full=Protein YIPF3; AltName: Full=Killer lineage protein 1; AltName: Full=Natural killer cell-specific antigen KLIP1; AltName: Full=YIP1 family member 3; Contains: RecName: Full=Protein YIPF3, 36 kDa form III;+++[D6RA04_HUMAN|Unreviewed]SubName: Full=Protein YIPF3 {ECO:0000313|Ensembl:ENSP00000390056};+++[D6RAY4_HUMAN|Unreviewed]SubName: Full=Protein YIPF3 {ECO:0000313|Ensembl:ENSP00000424629};+++[D6RBQ1_HUMAN|Unreviewed]SubName: Full=Protein YIPF3 {ECO:0000313|Ensembl:ENSP00000392699};+++[D6RFI3_HUMAN|Unreviewed]SubName: Full=Protein YIPF3 {ECO:0000313|Ensembl:ENSP00000421461}; Flags: Fragment;+++[D6RGY8_HUMAN|Unreviewed]SubName: Full=Protein YIPF3 {ECO:0000313|Ensembl:ENSP00000421094}; Flags: Fragment;+++[E7EQR8_HUMAN|Unreviewed]SubName: Full=Protein YIPF3 {ECO:0000313|Ensembl:ENSP00000425494};+++[H0Y9A1_HUMAN|Unreviewed]SubName: Full=Protein YIPF3 {ECO:0000313|Ensembl:ENSP00000423544}; Flags: Fragment;"]
[25871,"'NEPRO'",233,164,198.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0046872///metal ion binding+++GO:0005525///GTP binding","GO:0045665///negative regulation of neuron differentiation+++GO:0007275///multicellular organism development+++GO:0045747///positive regulation of Notch signaling pathway","IPR027951///Domain of unknown function DUF4477","[NEPRO_HUMAN|Reviewed]RecName: Full=Nucleolus and neural progenitor protein {ECO:0000305};+++[B4DHL5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53326 {ECO:0000313|EMBL:BAG58177.1};+++[B4DJ73_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59546 {ECO:0000313|EMBL:BAG58735.1};+++[B4DUV5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59436 {ECO:0000313|EMBL:BAG62467.1};+++[C9J9E3_HUMAN|Unreviewed]SubName: Full=Nucleolus and neural progenitor protein {ECO:0000313|Ensembl:ENSP00000417613}; Flags: Fragment;+++[E9PFF8_HUMAN|Unreviewed]SubName: Full=Nucleolus and neural progenitor protein {ECO:0000313|Ensembl:ENSP00000418309};+++[F2Z3E4_HUMAN|Unreviewed]SubName: Full=Nucleolus and neural progenitor protein {ECO:0000313|Ensembl:ENSP00000418902};+++[F8WBQ8_HUMAN|Unreviewed]SubName: Full=Nucleolus and neural progenitor protein {ECO:0000313|Ensembl:ENSP00000418133};+++[F8WC60_HUMAN|Unreviewed]SubName: Full=Nucleolus and neural progenitor protein {ECO:0000313|Ensembl:ENSP00000418677};+++[F8WDL7_HUMAN|Unreviewed]SubName: Full=Nucleolus and neural progenitor protein {ECO:0000313|Ensembl:ENSP00000420036};"]
[25893,"'TRIM58'",602.65,432.33,517.49,"04740///Olfactory transduction+++04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005622///intracellular","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003674///molecular_function+++GO:0045505///dynein intermediate chain binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0045504///dynein heavy chain binding+++GO:0016740///transferase activity","GO:0000209///protein polyubiquitination+++GO:1902838///regulation of nuclear migration along microtubule+++GO:0008150///biological_process+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0061931///positive regulation of erythrocyte enucleation+++GO:0016567///protein ubiquitination+++GO:0051865///protein autoubiquitination","IPR017452///GPCR, rhodopsin-like, 7TM+++IPR006574///SPRY-associated+++IPR000725///Olfactory receptor+++IPR003877///SPRY domain+++IPR003879///Butyrophylin-like, SPRY domain+++IPR001870///B30.2/SPRY domain+++IPR035787///E3 ubiquitin-protein ligase TRIM58, PRY/SPRY domain+++IPR017907///Zinc finger, RING-type, conserved site+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR001841///Zinc finger, RING-type+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR000315///B-box-type zinc finger+++IPR013083///Zinc finger, RING/FYVE/PHD-type","[TRI58_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase TRIM58; EC=2.3.2.27; AltName: Full=Protein BIA2; AltName: Full=RING-type E3 ubiquitin transferase TRIM58 {ECO:0000305}; AltName: Full=Tripartite motif-containing protein 58;"]
[2591,"'GALNT3'",223,312,267.5,"01100///Metabolic pathways+++00512///Mucin type O-glycan biosynthesis","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005794///Golgi apparatus+++GO:0032580///Golgi cisterna membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane","GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0030246///carbohydrate binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0030145///manganese ion binding","GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0016266///O-glycan processing+++GO:0018243///protein O-linked glycosylation via threonine+++GO:0006486///protein glycosylation+++GO:0018242///protein O-linked glycosylation via serine+++GO:0005975///carbohydrate metabolic process","IPR029044///Nucleotide-diphospho-sugar transferases+++IPR001173///Glycosyltransferase 2-like+++IPR000772///Ricin B, lectin domain+++IPR035992///Ricin B-like lectins","[GALT3_HUMAN|Reviewed]RecName: Full=Polypeptide N-acetylgalactosaminyltransferase 3; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 3; Short=GalNAc-T3; Short=pp-GaNTase 3; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 3; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3;+++[C9J2C3_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|Ensembl:ENSP00000412643}; Flags: Fragment;+++[C9J388_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|Ensembl:ENSP00000397112}; Flags: Fragment;+++[C9JW45_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|Ensembl:ENSP00000413694}; Flags: Fragment;+++[C9JXX2_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|Ensembl:ENSP00000413477}; Flags: Fragment;+++[C9JY57_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|Ensembl:ENSP00000399880}; Flags: Fragment;+++[E7EUL0_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|Ensembl:ENSP00000386955};+++[H7BZS4_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|Ensembl:ENSP00000391104}; Flags: Fragment;+++[Q68VJ6_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 3 {ECO:0000313|EMBL:CAD44536.1}; Flags: Fragment;"]
[259236,"'TMIE'",4,2,3,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,"GO:0007605///sensory perception of sound+++GO:0042472///inner ear morphogenesis","IPR032006///Transmembrane inner ear expressed protein","[TMIE_HUMAN|Reviewed]RecName: Full=Transmembrane inner ear expressed protein; Flags: Precursor;+++[A0A2R8YDZ8_HUMAN|Unreviewed]SubName: Full=Transmembrane inner ear-expressed protein {ECO:0000313|Ensembl:ENSP00000495111};"]
[25932,"'CLIC4'",3800,5303,4551.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0016363///nuclear matrix+++GO:0030054///cell junction+++GO:0005739///mitochondrion+++GO:0070062///extracellular exosome+++GO:0031410///cytoplasmic vesicle+++GO:0005813///centrosome+++GO:0005622///intracellular+++GO:0009986///cell surface+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005902///microvillus+++GO:0034707///chloride channel complex+++GO:0045177///apical part of cell+++GO:0005815///microtubule organizing center+++GO:0015630///microtubule cytoskeleton+++GO:0016021///integral component of membrane+++GO:0005911///cell-cell junction+++GO:0005634///nucleus+++GO:0030496///midbody+++GO:0015629///actin cytoskeleton+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0005254///chloride channel activity+++GO:0005244///voltage-gated ion channel activity","GO:0006811///ion transport+++GO:0001886///endothelial cell morphogenesis+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0035264///multicellular organism growth+++GO:0034765///regulation of ion transmembrane transport+++GO:0030154///cell differentiation+++GO:0061299///retina vasculature morphogenesis in camera-type eye+++GO:0006821///chloride transport+++GO:0071277///cellular response to calcium ion+++GO:0048754///branching morphogenesis of an epithelial tube+++GO:0009566///fertilization+++GO:0001525///angiogenesis+++GO:0030336///negative regulation of cell migration+++GO:0007035///vacuolar acidification+++GO:1902476///chloride transmembrane transport+++GO:0030216///keratinocyte differentiation+++GO:0051493///regulation of cytoskeleton organization+++GO:0034220///ion transmembrane transport","IPR030257///Chloride intracellular channel protein 4+++IPR010987///Glutathione S-transferase, C-terminal-like+++IPR036249///Thioredoxin-like superfamily+++IPR040079///Glutathione Transferase family+++IPR036282///Glutathione S-transferase, C-terminal domain superfamily+++IPR002946///Intracellular chloride channel","[CLIC4_HUMAN|Reviewed]RecName: Full=Chloride intracellular channel protein 4; AltName: Full=Intracellular chloride ion channel protein p64H1;+++[Q6FIC5_HUMAN|Unreviewed]RecName: Full=Chloride intracellular channel protein {ECO:0000256|RuleBase:RU362009};"]
[25950,"'RWDD3'",49.97,34.47,42.22,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:1902073///positive regulation of hypoxia-inducible factor-1alpha signaling pathway+++GO:0033235///positive regulation of protein sumoylation","IPR006575///RWD domain+++IPR038840///RWD domain-containing protein 3+++IPR016135///Ubiquitin-conjugating enzyme/RWD-like","[RWDD3_HUMAN|Reviewed]RecName: Full=RWD domain-containing protein 3; AltName: Full=RWD domain-containing sumoylation enhancer; Short=RSUME {ECO:0000303|PubMed:17956732};+++[D3DT49_HUMAN|Unreviewed]SubName: Full=RWD domain containing 3, isoform CRA_a {ECO:0000313|EMBL:EAW73022.1};"]
[25974,"'MMACHC'",113,122,117.5,"04977///Vitamin digestion and absorption","H00174///Methylmalonic aciduria (MMA)",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0031419///cobalamin binding+++GO:0032451///demethylase activity+++GO:0043295///glutathione binding+++GO:0042803///protein homodimerization activity+++GO:0033787///cyanocobalamin reductase (cyanide-eliminating) activity+++GO:0016491///oxidoreductase activity+++GO:0071949///FAD binding+++GO:0005515///protein binding","GO:0009235///cobalamin metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006749///glutathione metabolic process+++GO:0070988///demethylation+++GO:0009236///cobalamin biosynthetic process","IPR032037///Methylmalonic aciduria and homocystinuria type C family","[MMAC_HUMAN|Reviewed]RecName: Full=Methylmalonic aciduria and homocystinuria type C protein; EC=1.16.1.- {ECO:0000269|PubMed:21071249, ECO:0000269|PubMed:22642810, ECO:0000269|PubMed:25809485}; AltName: Full=CblC {ECO:0000303|PubMed:23415655, ECO:0000303|PubMed:25809485}; AltName: Full=Cyanocobalamin reductase (cyanide-eliminating);+++[A0A0C4DGU2_HUMAN|Unreviewed]SubName: Full=Methylmalonic aciduria and homocystinuria type C protein {ECO:0000313|Ensembl:ENSP00000478859};"]
[25998,"'IBTK'",317,537,427,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0019901///protein kinase binding+++GO:0030292///protein tyrosine kinase inhibitor activity","GO:0051209///release of sequestered calcium ion into cytosol+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0001933///negative regulation of protein phosphorylation","IPR002110///Ankyrin repeat+++IPR009091///Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II+++IPR000408///Regulator of chromosome condensation, RCC1+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily","[IBTK_HUMAN|Reviewed]RecName: Full=Inhibitor of Bruton tyrosine kinase; Short=IBtk;+++[B7ZLD4_HUMAN|Unreviewed]SubName: Full=IBTK protein {ECO:0000313|EMBL:AAI43737.1};+++[B7ZLE0_HUMAN|Unreviewed]SubName: Full=IBTK protein {ECO:0000313|EMBL:AAI43746.1};+++[D6R9F4_HUMAN|Unreviewed]SubName: Full=Inhibitor of Bruton tyrosine kinase {ECO:0000313|Ensembl:ENSP00000422136};+++[E7EPI0_HUMAN|Unreviewed]SubName: Full=Inhibitor of Bruton tyrosine kinase {ECO:0000313|Ensembl:ENSP00000426405};+++[E9PDR5_HUMAN|Unreviewed]SubName: Full=Inhibitor of Bruton tyrosine kinase {ECO:0000313|Ensembl:ENSP00000422762};+++[H0Y9N7_HUMAN|Unreviewed]SubName: Full=Inhibitor of Bruton tyrosine kinase {ECO:0000313|Ensembl:ENSP00000424634}; Flags: Fragment;"]
[26018,"'LRIG1'",227,327,277,{"$nulls":4},"GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031012///extracellular matrix+++GO:0005739///mitochondrion","GO:0003910///DNA ligase (ATP) activity+++GO:0046872///metal ion binding+++GO:0016874///ligase activity+++GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0003909///DNA ligase activity","GO:0006310///DNA recombination+++GO:1903461///Okazaki fragment processing involved in mitotic DNA replication+++GO:0006284///base-excision repair+++GO:0033151///V(D)J recombination+++GO:0009653///anatomical structure morphogenesis+++GO:0006260///DNA replication+++GO:0051103///DNA ligation involved in DNA repair+++GO:0006281///DNA repair+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0007605///sensory perception of sound+++GO:0006298///mismatch repair+++GO:0006266///DNA ligation+++GO:0051301///cell division+++GO:0032474///otolith morphogenesis+++GO:0007049///cell cycle+++GO:0071897///DNA biosynthetic process+++GO:0022405///hair cycle process+++GO:0006273///lagging strand elongation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0060384///innervation+++GO:0006283///transcription-coupled nucleotide-excision repair","IPR013098///Immunoglobulin I-set+++IPR003591///Leucine-rich repeat, typical subtype+++IPR001611///Leucine-rich repeat+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR003599///Immunoglobulin subtype+++IPR003598///Immunoglobulin subtype 2+++IPR007110///Immunoglobulin-like domain+++IPR013783///Immunoglobulin-like fold+++IPR000372///Leucine-rich repeat N-terminal domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR032675///Leucine-rich repeat domain superfamily","[LRIG1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 1; Short=LIG-1 {ECO:0000303|Ref.2}; Flags: Precursor;+++[B4E135_HUMAN|Unreviewed]SubName: Full=DNA ligase 1 {ECO:0000313|Ensembl:ENSP00000445928}; SubName: Full=cDNA FLJ52385, highly similar to DNA ligase 1 {ECO:0000313|EMBL:BAG64647.1};+++[M0QY71_HUMAN|Unreviewed]SubName: Full=DNA ligase 1 {ECO:0000313|Ensembl:ENSP00000469638}; Flags: Fragment;+++[M0R0Q7_HUMAN|Unreviewed]RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617}; EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};+++[M0R1G7_HUMAN|Unreviewed]SubName: Full=DNA ligase 1 {ECO:0000313|Ensembl:ENSP00000471861}; Flags: Fragment;+++[M0R1S4_HUMAN|Unreviewed]SubName: Full=DNA ligase 1 {ECO:0000313|Ensembl:ENSP00000472085}; Flags: Fragment;+++[M0R254_HUMAN|Unreviewed]SubName: Full=DNA ligase 1 {ECO:0000313|Ensembl:ENSP00000472331}; Flags: Fragment;+++[Q5XWD3_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat protein LRIG1 {ECO:0000313|EMBL:AAU44786.1};+++[Q76GR4_HUMAN|Unreviewed]SubName: Full=Ligase I, DNA, ATP-dependent {ECO:0000313|EMBL:BAC81763.1}; Flags: Fragment;"]
[26038,"'CHD5'",118,136,127,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0016020///membrane+++GO:0000792///heterochromatin+++GO:0016581///NuRD complex","GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0004386///helicase activity+++GO:0005524///ATP binding+++GO:0061628///H3K27me3 modified histone binding","GO:0021895///cerebral cortex neuron differentiation+++GO:0006351///transcription, DNA-templated+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:1901798///positive regulation of signal transduction by p53 class mediator+++GO:0098532///histone H3-K27 trimethylation+++GO:0043967///histone H4 acetylation+++GO:0008285///negative regulation of cell proliferation+++GO:0060850///regulation of transcription involved in cell fate commitment","IPR002464///DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site+++IPR012957///CHD, C-terminal 2+++IPR016197///Chromo-like domain superfamily+++IPR012958///CHD, N-terminal+++IPR001650///Helicase, C-terminal+++IPR001965///Zinc finger, PHD-type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR009462///Domain of unknown function DUF1086+++IPR038718///SNF2-like, N-terminal domain superfamily+++IPR019787///Zinc finger, PHD-finger+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR023780///Chromo domain+++IPR028727///Chromodomain-helicase-DNA-binding protein 5+++IPR000330///SNF2-related, N-terminal domain+++IPR009463///Domain of unknown function DUF1087+++IPR000953///Chromo/chromo shadow domain+++IPR019786///Zinc finger, PHD-type, conserved site","[CHD5_HUMAN|Reviewed]RecName: Full=Chromodomain-helicase-DNA-binding protein 5; Short=CHD-5; EC=3.6.4.12; AltName: Full=ATP-dependent helicase CHD5;"]
[26053,"'AUTS2'",939,1275,1107,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0030426///growth cone+++GO:0005634///nucleus+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0010494///cytoplasmic stress granule+++GO:0005856///cytoskeleton+++GO:0005730///nucleolus","GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0003697///single-stranded DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000166///nucleotide binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0003727///single-stranded RNA binding+++GO:0003682///chromatin binding","GO:0010592///positive regulation of lamellipodium assembly+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006351///transcription, DNA-templated+++GO:0048675///axon extension+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0035022///positive regulation of Rac protein signal transduction+++GO:0032197///transposition, RNA-mediated+++GO:0001764///neuron migration+++GO:2000620///positive regulation of histone H4-K16 acetylation+++GO:0031532///actin cytoskeleton reorganization+++GO:0097484///dendrite extension+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0051571///positive regulation of histone H3-K4 methylation","IPR023246///Autism susceptibility gene 2 protein","[AUTS2_HUMAN|Reviewed]RecName: Full=Autism susceptibility gene 2 protein;"]
[26085,"'KLK13'",6,14,10,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0030141///secretory granule+++GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0005515///protein binding+++GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008233///peptidase activity","GO:0070268///cornification+++GO:0006508///proteolysis+++GO:0016485///protein processing","IPR001254///Serine proteases, trypsin domain+++IPR033116///Serine proteases, trypsin family, serine active site+++IPR001314///Peptidase S1A, chymotrypsin family+++IPR018114///Serine proteases, trypsin family, histidine active site+++IPR009003///Peptidase S1, PA clan","[KLK13_HUMAN|Reviewed]RecName: Full=Kallikrein-13; EC=3.4.21.-; AltName: Full=Kallikrein-like protein 4; Short=KLK-L4; Flags: Precursor;+++[A0A1R3UCE9_HUMAN|Unreviewed]SubName: Full=Kallikrein L {ECO:0000313|EMBL:SFW93210.1};+++[B5BUM9_HUMAN|Unreviewed]SubName: Full=Kallikrein 13 {ECO:0000313|EMBL:BAG70279.1}; Flags: Fragment;+++[M0R218_HUMAN|Unreviewed]SubName: Full=Kallikrein 13, isoform CRA_b {ECO:0000313|EMBL:EAW71980.1}; SubName: Full=Kallikrein-13 {ECO:0000313|Ensembl:ENSP00000472248};+++[Q5BQ95_HUMAN|Unreviewed]SubName: Full=Kallikrein 13 splice variant 7 {ECO:0000313|EMBL:AAX30055.1}; SubName: Full=Kallikrein 13 splice variant 8 {ECO:0000313|EMBL:AAX30056.1}; SubName: Full=Kallikrein-13 {ECO:0000313|Ensembl:ENSP00000365995};+++[Q5BQ97_HUMAN|Unreviewed]SubName: Full=Kallikrein 13 splice variant 5 {ECO:0000313|EMBL:AAX30053.1}; SubName: Full=Kallikrein 13 splice variant 6 {ECO:0000313|EMBL:AAX30054.1}; SubName: Full=Kallikrein-13 {ECO:0000313|Ensembl:ENSP00000392640};+++[Q5BQ99_HUMAN|Unreviewed]SubName: Full=Kallikrein 13 splice variant 4 {ECO:0000313|EMBL:AAX30052.1}; SubName: Full=Kallikrein-13 {ECO:0000313|Ensembl:ENSP00000156476};+++[Q86VI7_HUMAN|Unreviewed]SubName: Full=Kallikrein 13 splicing variant 2 {ECO:0000313|EMBL:BAC75826.1}; SubName: Full=Kallikrein 13, isoform CRA_c {ECO:0000313|EMBL:EAW71981.1}; SubName: Full=Kallikrein-13 {ECO:0000313|Ensembl:ENSP00000470245};"]
[26118,"'WSB1'",911,1477,1194,{"$nulls":4},"GO:0005829///cytosol+++GO:0005622///intracellular","GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0008150///biological_process+++GO:0035556///intracellular signal transduction+++GO:0016567///protein ubiquitination+++GO:0000209///protein polyubiquitination","IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR001496///SOCS box domain+++IPR019775///WD40 repeat, conserved site+++IPR001680///WD40 repeat+++IPR036036///SOCS box-like domain superfamily+++IPR036322///WD40-repeat-containing domain superfamily+++IPR020472///G-protein beta WD-40 repeat+++IPR017986///WD40-repeat-containing domain+++IPR011047///Quinoprotein alcohol dehydrogenase-like superfamily","[WSB1_HUMAN|Reviewed]RecName: Full=WD repeat and SOCS box-containing protein 1; Short=WSB-1; AltName: Full=SOCS box-containing WD protein SWiP-1;+++[A0A024QZ36_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW51029.1};+++[A0A024QZ51_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW51030.1};+++[A0JLP1_HUMAN|Unreviewed]SubName: Full=WSB1 protein {ECO:0000313|EMBL:AAH05226.1}; Flags: Fragment;+++[B4DGB8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58059, highly similar to WD repeat and SOCS box-containing protein 1 {ECO:0000313|EMBL:BAG57729.1};+++[B4DTL1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59301, highly similar to WD repeat and SOCS box-containing protein 1 {ECO:0000313|EMBL:BAG62023.1};+++[J3KRG6_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000313|Ensembl:ENSP00000461991};+++[J3KS88_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000313|Ensembl:ENSP00000462365}; Flags: Fragment;+++[J3KSQ3_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000313|Ensembl:ENSP00000462595};+++[J3KT03_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000313|Ensembl:ENSP00000462737}; Flags: Fragment;+++[J3KTB3_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000313|Ensembl:ENSP00000462900}; Flags: Fragment;+++[J3QLM8_HUMAN|Unreviewed]SubName: Full=WD repeat and SOCS box-containing protein 1 {ECO:0000313|Ensembl:ENSP00000463621};+++[Q8NC76_HUMAN|Unreviewed]SubName: Full=cDNA FLJ90436 fis, clone NT2RP3000820, weakly similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA {ECO:0000313|EMBL:BAC11291.1};"]
[26147,"'PHF19'",95,108,101.5,"05169///Epstein-Barr virus infection+++04210///Apoptosis+++04064///NF-kappa B signaling pathway+++05222///Small cell lung cancer+++05203///Viral carcinogenesis+++05200///Pathways in cancer+++04668///TNF signaling pathway+++05168///Herpes simplex infection+++05202///Transcriptional misregulation in cancer",{"$nulls":3},"GO:0035098///ESC/E(Z) complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0035064///methylated histone binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0031491///nucleosome binding+++GO:0043565///sequence-specific DNA binding","GO:0045814///negative regulation of gene expression, epigenetic+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0019827///stem cell population maintenance+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0048863///stem cell differentiation+++GO:0061087///positive regulation of histone H3-K27 methylation","IPR011011///Zinc finger, FYVE/PHD-type+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR025894///Polycomb-like MTF2 factor 2, C-terminal domain+++IPR019787///Zinc finger, PHD-finger+++IPR001965///Zinc finger, PHD-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR002999///Tudor domain","[PHF19_HUMAN|Reviewed]RecName: Full=PHD finger protein 19; AltName: Full=Polycomb-like protein 3; Short=hPCL3;+++[A0A087X169_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000483946};+++[B0QZ50_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000395938}; Flags: Fragment;+++[B0QZ51_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000404655}; Flags: Fragment;+++[B0QZ72_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000408479}; Flags: Fragment;+++[B7Z887_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55009, highly similar to Homo sapiens PHD finger protein 19 (PHF19), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH13873.1};+++[B7Z8H3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53261, highly similar to Homo sapiens PHD finger protein 19 (PHF19), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH13959.1};+++[F5H8K3_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000407433};+++[X6RER8_HUMAN|Unreviewed]SubName: Full=PHD finger protein 19 {ECO:0000313|Ensembl:ENSP00000397935}; Flags: Fragment;"]
[261726,"'TIPRL'",424,567,495.5,"04138///Autophagy - yeast",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0007165///signal transduction+++GO:0031929///TOR signaling+++GO:0000077///DNA damage checkpoint","IPR007303///TIP41-like protein","[TIPRL_HUMAN|Reviewed]RecName: Full=TIP41-like protein; AltName: Full=Putative MAPK-activating protein PM10; AltName: Full=Type 2A-interacting protein; Short=TIP;"]
[2622,"'GAS8'",229,222,225.5,null,"H00564///Primary ciliary dyskinesia",null,null,"GO:0031514///motile cilium+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005794///Golgi apparatus+++GO:0097729///9+2 motile cilium+++GO:0005930///axoneme+++GO:0005929///cilium+++GO:0036126///sperm flagellum+++GO:0042995///cell projection+++GO:0036064///ciliary basal body+++GO:0015630///microtubule cytoskeleton","GO:0008017///microtubule binding+++GO:0017137///Rab GTPase binding+++GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0048870///cell motility+++GO:0060294///cilium movement involved in cell motility+++GO:0007420///brain development+++GO:1904526///regulation of microtubule binding+++GO:0034613///cellular protein localization+++GO:0008285///negative regulation of cell proliferation+++GO:0007368///determination of left/right symmetry+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0003351///epithelial cilium movement+++GO:1903566///positive regulation of protein localization to cilium+++GO:0030317///flagellated sperm motility+++GO:0035082///axoneme assembly","IPR025593///Growth arrest-specific protein 8 domain+++IPR039308///Growth arrest-specific protein 8","[DRC4_HUMAN|Reviewed]RecName: Full=Dynein regulatory complex subunit 4 {ECO:0000303|PubMed:27120127}; AltName: Full=Growth arrest-specific protein 11; Short=GAS-11; AltName: Full=Growth arrest-specific protein 8; Short=GAS-8;+++[A0A087WZT7_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex subunit 4 {ECO:0000313|Ensembl:ENSP00000482877};+++[B7Z1U9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52408, highly similar to Growth-arrest-specific protein 8 {ECO:0000313|EMBL:BAH11635.1};+++[H3BME0_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex subunit 4 {ECO:0000313|Ensembl:ENSP00000454343};+++[H3BP65_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex subunit 4 {ECO:0000313|Ensembl:ENSP00000455172}; Flags: Fragment;+++[H3BQT7_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex subunit 4 {ECO:0000313|Ensembl:ENSP00000455936};+++[H3BUA7_HUMAN|Unreviewed]SubName: Full=Dynein regulatory complex subunit 4 {ECO:0000313|Ensembl:ENSP00000457554}; Flags: Fragment;"]
[2625,"'GATA3'",37,53,45,"04658///Th1 and Th2 cell differentiation+++04659///Th17 cell differentiation+++04928///Parathyroid hormone synthesis, secretion and action","H01360///Allergic rhinitis+++H01271///Hypoparathyroidism with sensorineural deafness and renal dysplasia",null,null,"GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005134///interleukin-2 receptor binding+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0046983///protein dimerization activity+++GO:0003712///transcription coregulator activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0071837///HMG box domain binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0070888///E-box binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding","GO:0072107///positive regulation of ureteric bud formation+++GO:0045786///negative regulation of cell cycle+++GO:0042472///inner ear morphogenesis+++GO:0072179///nephric duct formation+++GO:2000553///positive regulation of T-helper 2 cell cytokine production+++GO:0048485///sympathetic nervous system development+++GO:0009791///post-embryonic development+++GO:0045061///thymic T cell selection+++GO:0007596///blood coagulation+++GO:0009653///anatomical structure morphogenesis+++GO:0050728///negative regulation of inflammatory response+++GO:0060676///ureteric bud formation+++GO:0001806///type IV hypersensitivity+++GO:0035457///cellular response to interferon-alpha+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045064///T-helper 2 cell differentiation+++GO:0007399///nervous system development+++GO:0001764///neuron migration+++GO:2000683///regulation of cellular response to X-ray+++GO:0061085///regulation of histone H3-K27 methylation+++GO:0060374///mast cell differentiation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060037///pharyngeal system development+++GO:0045087///innate immune response+++GO:0001775///cell activation+++GO:0045599///negative regulation of fat cell differentiation+++GO:0071599///otic vesicle development+++GO:0001701///in utero embryonic development+++GO:0035898///parathyroid hormone secretion+++GO:2000667///positive regulation of interleukin-13 secretion+++GO:2000611///positive regulation of thyroid hormone generation+++GO:2000703///negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation+++GO:0009615///response to virus+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001709///cell fate determination+++GO:0032703///negative regulation of interleukin-2 production+++GO:0008584///male gonad development+++GO:0043627///response to estrogen+++GO:0061290///canonical Wnt signaling pathway involved in metanephric kidney development+++GO:0072602///interleukin-4 secretion+++GO:0071773///cellular response to BMP stimulus+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0003215///cardiac right ventricle morphogenesis+++GO:0030217///T cell differentiation+++GO:0060065///uterus development+++GO:0035799///ureter maturation+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0043583///ear development+++GO:0050852///T cell receptor signaling pathway+++GO:0032736///positive regulation of interleukin-13 production+++GO:0031929///TOR signaling+++GO:2000734///negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation+++GO:0071345///cellular response to cytokine stimulus+++GO:0000902///cell morphogenesis+++GO:0042035///regulation of cytokine biosynthetic process+++GO:0009967///positive regulation of signal transduction+++GO:0006366///transcription by RNA polymerase II+++GO:0032753///positive regulation of interleukin-4 production+++GO:2000146///negative regulation of cell motility+++GO:0019221///cytokine-mediated signaling pathway+++GO:0033600///negative regulation of mammary gland epithelial cell proliferation+++GO:0048538///thymus development+++GO:2000352///negative regulation of endothelial cell apoptotic process+++GO:0043370///regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0003180///aortic valve morphogenesis+++GO:0060231///mesenchymal to epithelial transition+++GO:0010629///negative regulation of gene expression+++GO:2000114///regulation of establishment of cell polarity+++GO:0090102///cochlea development+++GO:2000607///negative regulation of cell proliferation involved in mesonephros development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0035162///embryonic hemopoiesis+++GO:0030218///erythrocyte differentiation+++GO:0072001///renal system development+++GO:0045582///positive regulation of T cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048568///embryonic organ development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0072182///regulation of nephron tubule epithelial cell differentiation+++GO:0072676///lymphocyte migration+++GO:0048469///cell maturation+++GO:0048589///developmental growth+++GO:0001822///kidney development+++GO:0072178///nephric duct morphogenesis+++GO:0060017///parathyroid gland development+++GO:0042421///norepinephrine biosynthetic process+++GO:0010628///positive regulation of gene expression+++GO:0002088///lens development in camera-type eye+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0008285///negative regulation of cell proliferation+++GO:0010332///response to gamma radiation+++GO:0030182///neuron differentiation+++GO:0033077///T cell differentiation in thymus+++GO:0006338///chromatin remodeling+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0002376///immune system process+++GO:0007411///axon guidance+++GO:0045597///positive regulation of cell differentiation+++GO:0010595///positive regulation of endothelial cell migration+++GO:0006952///defense response+++GO:0007165///signal transduction+++GO:0043523///regulation of neuron apoptotic process+++GO:0010975///regulation of neuron projection development+++GO:0032754///positive regulation of interleukin-5 production+++GO:0045471///response to ethanol+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0048872///homeostasis of number of cells+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0032689///negative regulation of interferon-gamma production+++GO:0071442///positive regulation of histone H3-K14 acetylation+++GO:0006959///humoral immune response+++GO:0001823///mesonephros development+++GO:0002572///pro-T cell differentiation+++GO:0071353///cellular response to interleukin-4+++GO:2000664///positive regulation of interleukin-5 secretion+++GO:0016579///protein deubiquitination+++GO:0072643///interferon-gamma secretion+++GO:0003281///ventricular septum development+++GO:0042493///response to drug+++GO:1901536///negative regulation of DNA demethylation+++GO:2000617///positive regulation of histone H3-K9 acetylation+++GO:0001819///positive regulation of cytokine production","IPR029521///Transcription factor GATA-3+++IPR039355///Transcription factor GATA+++IPR016374///Transcription factor, GATA-2/3+++IPR013088///Zinc finger, NHR/GATA-type+++IPR000679///Zinc finger, GATA-type","[GATA3_HUMAN|Reviewed]RecName: Full=Trans-acting T-cell-specific transcription factor GATA-3; AltName: Full=GATA-binding factor 3;+++[A0A2R8Y2A9_HUMAN|Unreviewed]SubName: Full=Trans-acting T-cell-specific transcription factor GATA-3 {ECO:0000313|Ensembl:ENSP00000493486}; Flags: Fragment;+++[A0A2R8Y4T2_HUMAN|Unreviewed]SubName: Full=Trans-acting T-cell-specific transcription factor GATA-3 {ECO:0000313|Ensembl:ENSP00000494284}; Flags: Fragment;"]
[26270,"'FBXO6'",195.8,144.84,170.32,"04141///Protein processing in endoplasmic reticulum",null,"M00382///SCF-FBS complex",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0019005///SCF ubiquitin ligase complex+++GO:0044322///endoplasmic reticulum quality control compartment","GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0030246///carbohydrate binding+++GO:0005515///protein binding","GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0000077///DNA damage checkpoint+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0006508///proteolysis+++GO:0006986///response to unfolded protein+++GO:0006516///glycoprotein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0043687///post-translational protein modification+++GO:0006281///DNA repair","IPR007397///F-box associated (FBA) domain+++IPR036047///F-box-like domain superfamily+++IPR001810///F-box domain+++IPR039752///F-box only protein+++IPR008979///Galactose-binding-like domain superfamily","[FBX6_HUMAN|Reviewed]RecName: Full=F-box only protein 6; AltName: Full=F-box protein that recognizes sugar chains 2; AltName: Full=F-box/G-domain protein 2;+++[J3KQ72_HUMAN|Unreviewed]SubName: Full=F-box only protein 6 {ECO:0000313|Ensembl:ENSP00000388781}; Flags: Fragment;"]
[26290,"'GALNT8'",0,1,0.5,"00512///Mucin type O-glycan biosynthesis+++01100///Metabolic pathways","H01193///Familial tumoral calcinosis (FTC)+++H01439///Williams-Beuren syndrome+++H00020///Colorectal cancer","M00056///O-glycan biosynthesis, mucin type core","R05907///UDP-N-acetyl-D-galactosamine + [Protein]-L-serine <=> UDP + Tn antigen","GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus","GO:0004653///polypeptide N-acetylgalactosaminyltransferase activity+++GO:0030246///carbohydrate binding+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0016266///O-glycan processing+++GO:0006486///protein glycosylation","IPR000772///Ricin B, lectin domain+++IPR001173///Glycosyltransferase 2-like+++IPR035992///Ricin B-like lectins+++IPR029044///Nucleotide-diphospho-sugar transferases","[GALT8_HUMAN|Reviewed]RecName: Full=Probable polypeptide N-acetylgalactosaminyltransferase 8; EC=2.4.1.41; AltName: Full=Polypeptide GalNAc transferase 8; Short=GalNAc-T8; Short=pp-GaNTase 8; AltName: Full=Protein-UDP acetylgalactosaminyltransferase 8; AltName: Full=UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8;+++[H0YFU9_HUMAN|Unreviewed]SubName: Full=Probable polypeptide N-acetylgalactosaminyltransferase 8 {ECO:0000313|Ensembl:ENSP00000440383}; Flags: Fragment;+++[H0YGU9_HUMAN|Unreviewed]SubName: Full=Probable polypeptide N-acetylgalactosaminyltransferase 8 {ECO:0000313|Ensembl:ENSP00000444876}; Flags: Fragment;+++[Q68VJ3_HUMAN|Unreviewed]SubName: Full=Polypeptide N-acetylgalactosaminyltransferase 8 {ECO:0000313|EMBL:CAD44539.1}; Flags: Fragment;"]
[2642,"'GCGR'",3,0,1.5,"04080///Neuroactive ligand-receptor interaction+++04922///Glucagon signaling pathway","H01572///Cole-Carpenter syndrome",null,null,"GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0004930///G protein-coupled receptor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0017046///peptide hormone binding+++GO:0004967///glucagon receptor activity","GO:0070873///regulation of glycogen metabolic process+++GO:0071377///cellular response to glucagon stimulus+++GO:0042594///response to starvation+++GO:0042593///glucose homeostasis+++GO:0007166///cell surface receptor signaling pathway+++GO:0006091///generation of precursor metabolites and energy+++GO:0006887///exocytosis+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007584///response to nutrient+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0008217///regulation of blood pressure+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0009755///hormone-mediated signaling pathway","IPR003290///GPCR, family 2, glucagon-like peptide-1/glucagon receptor+++IPR017983///GPCR, family 2, secretin-like, conserved site+++IPR000832///GPCR, family 2, secretin-like+++IPR036445///GPCR family 2, extracellular hormone receptor domain superfamily+++IPR017981///GPCR, family 2-like+++IPR003291///GPCR, family 2, glucagon receptor+++IPR001879///GPCR, family 2, extracellular hormone receptor domain","[GLR_HUMAN|Reviewed]RecName: Full=Glucagon receptor; Short=GL-R; Flags: Precursor;+++[I3L1L8_HUMAN|Unreviewed]SubName: Full=Glucagon receptor {ECO:0000313|Ensembl:ENSP00000458930}; Flags: Fragment;+++[I3L454_HUMAN|Unreviewed]SubName: Full=Glucagon receptor {ECO:0000313|Ensembl:ENSP00000460976};"]
[26503,"'SLC17A5'",601,641,621,"04142///Lysosome","H00147///Sialuria",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0030672///synaptic vesicle membrane+++GO:0005887///integral component of plasma membrane+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0030054///cell junction","GO:0015293///symporter activity+++GO:0005351///carbohydrate:proton symporter activity+++GO:0015538///sialic acid:proton symporter activity+++GO:0015136///sialic acid transmembrane transporter activity","GO:0008643///carbohydrate transport+++GO:0006811///ion transport+++GO:0034219///carbohydrate transmembrane transport+++GO:1902600///proton transmembrane transport+++GO:0015739///sialic acid transport+++GO:0055085///transmembrane transport+++GO:0006820///anion transport+++GO:0006865///amino acid transport+++GO:0009617///response to bacterium","IPR020846///Major facilitator superfamily domain+++IPR036259///MFS transporter superfamily+++IPR011701///Major facilitator superfamily","[S17A5_HUMAN|Reviewed]RecName: Full=Sialin; AltName: Full=H(+)/nitrate cotransporter; AltName: Full=H(+)/sialic acid cotransporter; Short=AST; AltName: Full=Membrane glycoprotein HP59; AltName: Full=Solute carrier family 17 member 5; AltName: Full=Vesicular H(+)/Aspartate-glutamate cotransporter;+++[H0UI05_HUMAN|Unreviewed]SubName: Full=Solute carrier family 17 (Anion/sugar transporter), member 5, isoform CRA_a {ECO:0000313|EMBL:EAW48757.1};"]
[26524,"'LATS2'",716,897,806.5,"04214///Apoptosis - fly+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species",null,"M00683///Hippo signaling",null,"GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding","GO:0006468///protein phosphorylation+++GO:0009755///hormone-mediated signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0007049///cell cycle+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016310///phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0035556///intracellular signal transduction+++GO:0051301///cell division+++GO:0035329///hippo signaling+++GO:0046620///regulation of organ growth+++GO:0018105///peptidyl-serine phosphorylation","IPR017441///Protein kinase, ATP binding site+++IPR008271///Serine/threonine-protein kinase, active site+++IPR009060///UBA-like superfamily+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR000961///AGC-kinase, C-terminal+++IPR015940///Ubiquitin-associated domain","[LATS2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase LATS2; EC=2.7.11.1; AltName: Full=Kinase phosphorylated during mitosis protein; AltName: Full=Large tumor suppressor homolog 2; AltName: Full=Serine/threonine-protein kinase kpm; AltName: Full=Warts-like kinase;+++[A0A024RDM3_HUMAN|Unreviewed]SubName: Full=LATS, large tumor suppressor, homolog 2 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAX08287.1};"]
[26608,"'TBL2'",552,427,489.5,{"$nulls":4},"GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0031369///translation initiation factor binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0051219///phosphoprotein binding+++GO:0019901///protein kinase binding","GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0071456///cellular response to hypoxia+++GO:0042149///cellular response to glucose starvation","IPR036322///WD40-repeat-containing domain superfamily+++IPR001680///WD40 repeat+++IPR017986///WD40-repeat-containing domain+++IPR019775///WD40 repeat, conserved site+++IPR020472///G-protein beta WD-40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[TBL2_HUMAN|Reviewed]RecName: Full=Transducin beta-like protein 2; AltName: Full=WS beta-transducin repeats protein; Short=WS-betaTRP; AltName: Full=Williams-Beuren syndrome chromosomal region 13 protein;+++[A0A087WXC6_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000480898}; Flags: Fragment;+++[A0A0S2Z5C1_HUMAN|Unreviewed]SubName: Full=Transducin-like 2 isoform 3 {ECO:0000313|EMBL:ALQ34056.1};+++[A0A0S2Z5F3_HUMAN|Unreviewed]SubName: Full=Transducin-like 2 isoform 1 {ECO:0000313|EMBL:ALQ34055.1}; Flags: Fragment;+++[E9PF19_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000413979};+++[F2Z3G3_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000406418};+++[F8WB62_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000410737};+++[F8WBD9_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000414865};+++[F8WBP2_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000398195};+++[F8WCC7_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000400569};+++[F8WCR3_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000404242};+++[F8WDI9_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000409820};+++[F8WEC3_HUMAN|Unreviewed]SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000408255};+++[Q96E41_HUMAN|Unreviewed]SubName: Full=TBL2 protein {ECO:0000313|EMBL:AAH12938.1}; SubName: Full=Transducin beta-like protein 2 {ECO:0000313|Ensembl:ENSP00000484750};"]
[2669,"'GEM'",90,111,100.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016020///membrane+++GO:0030496///midbody+++GO:0072686///mitotic spindle+++GO:0051233///spindle midzone+++GO:0005634///nucleus","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0005516///calmodulin binding+++GO:0019003///GDP binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0000287///magnesium ion binding","GO:1901842///negative regulation of high voltage-gated calcium channel activity+++GO:0007165///signal transduction+++GO:0000278///mitotic cell cycle+++GO:0006955///immune response+++GO:0051310///metaphase plate congression+++GO:0007166///cell surface receptor signaling pathway+++GO:0051276///chromosome organization","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001806///Small GTPase+++IPR017358///Ras-related small G protein, RGK family+++IPR020849///Small GTPase superfamily, Ras-type+++IPR005225///Small GTP-binding protein domain","[GEM_HUMAN|Reviewed]RecName: Full=GTP-binding protein GEM; AltName: Full=GTP-binding mitogen-induced T-cell protein; AltName: Full=RAS-like protein KIR;+++[A0A024R9F5_HUMAN|Unreviewed]RecName: Full=GTP-binding protein {ECO:0000256|PIRNR:PIRNR038017};+++[E5RJF9_HUMAN|Unreviewed]SubName: Full=GTP-binding protein GEM {ECO:0000313|Ensembl:ENSP00000428258}; Flags: Fragment;"]
[2677,"'GGCX'",1113,1359,1236,"00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01110///Biosynthesis of secondary metabolites","H00995///Combined deficiency of vitamin K-dependent clotting factors (VKCFD)+++H01205///Coumarin resistance+++H00560///Pseudoxanthoma elasticum","M00609///Cysteine biosynthesis, methionine => cysteine+++M00034///Methionine salvage pathway+++M00035///Methionine degradation+++M00368///Ethylene biosynthesis, methionine => ethylene","R05144///peptidyl-glutamate 4-carboxylase (2-methyl-3-phytyl-1,4-naphthoquinone-epoxidizing)   Gla protein + Vitamin K1 epoxide + H2O <=> Gla protein precursor + Phylloquinol + CO2 + Oxygen+++R09991///peptidyl-glutamate 4-carboxylase (menaquinone-epoxidizing)   2,3-Epoxymenaquinone + Gla protein + H2O <=> Menaquinol + Gla protein precursor + CO2 + Oxygen","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0016829///lyase activity+++GO:0008488///gamma-glutamyl carboxylase activity","GO:0007596///blood coagulation+++GO:0006464///cellular protein modification process+++GO:0017187///peptidyl-glutamic acid carboxylation","IPR011051///RmlC-like cupin domain superfamily+++IPR007782///Vitamin K-dependent gamma-carboxylase+++IPR011020///HTTM","[VKGC_HUMAN|Reviewed]RecName: Full=Vitamin K-dependent gamma-carboxylase; EC=4.1.1.90 {ECO:0000269|PubMed:17073445}; AltName: Full=Gamma-glutamyl carboxylase; AltName: Full=Peptidyl-glutamate 4-carboxylase; AltName: Full=Vitamin K gamma glutamyl carboxylase;+++[A7YA96_HUMAN|Unreviewed]SubName: Full=Gamma-glutamyl carboxylase {ECO:0000313|EMBL:ABV02114.1}; SubName: Full=Gamma-glutymyl carboxylase {ECO:0000313|EMBL:ACF70731.1}; SubName: Full=cDNA, FLJ93613, highly similar to Homo sapiens gamma-glutamyl carboxylase (GGCX), mRNA {ECO:0000313|EMBL:BAG35946.1};+++[F8WB98_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent gamma-carboxylase {ECO:0000313|Ensembl:ENSP00000390748};+++[F8WCF0_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent gamma-carboxylase {ECO:0000313|Ensembl:ENSP00000400384};+++[F8WDU9_HUMAN|Unreviewed]SubName: Full=Vitamin K-dependent gamma-carboxylase {ECO:0000313|Ensembl:ENSP00000389426};"]
[2697,"'GJA1'",1523,2122,1822.5,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04540///Gap junction","H00449///Oculodentodigital dysplasia+++H00605///Deafness, autosomal recessive+++H00710///Erythrokeratodermia variabilis+++H01272///Hypoplastic left heart syndrome (HLHS)+++H00547///Atrioventricular septal defect+++H01095///Syndactyly",null,null,"GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0005921///gap junction+++GO:0005886///plasma membrane+++GO:0014704///intercalated disc+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0005922///connexin complex+++GO:0005783///endoplasmic reticulum+++GO:0030660///Golgi-associated vesicle membrane+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0000139///Golgi membrane","GO:0022857///transmembrane transporter activity+++GO:0015075///ion transmembrane transporter activity+++GO:0055077///gap junction hemi-channel activity+++GO:0043014///alpha-tubulin binding+++GO:1903763///gap junction channel activity involved in cell communication by electrical coupling+++GO:0005243///gap junction channel activity+++GO:0086075///gap junction channel activity involved in cardiac conduction electrical coupling+++GO:0005515///protein binding","GO:0007267///cell-cell signaling+++GO:0099111///microtubule-based transport+++GO:0030308///negative regulation of cell growth+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0007165///signal transduction+++GO:0016264///gap junction assembly+++GO:0034220///ion transmembrane transport+++GO:0007507///heart development+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0007154///cell communication+++GO:0006936///muscle contraction+++GO:0086014///atrial cardiac muscle cell action potential+++GO:0010644///cell communication by electrical coupling","IPR019570///Gap junction protein, cysteine-rich domain+++IPR038359///Connexin, N-terminal domain superfamily+++IPR017990///Connexin, conserved site+++IPR035091///Gap junction alpha-1 protein (Cx43), alpha helix domain superfamily+++IPR034634///Connexin, C-terminal+++IPR000500///Connexin+++IPR002261///Gap junction alpha-1 protein (Cx43)+++IPR013124///Gap junction alpha-1 protein (Cx43), C-terminal+++IPR013092///Connexin, N-terminal","[CXA1_HUMAN|Reviewed]RecName: Full=Gap junction alpha-1 protein; AltName: Full=Connexin-43; Short=Cx43; AltName: Full=Gap junction 43 kDa heart protein;"]
[26993,"'AKAP8L'",1155,1102,1128.5,"05169///Epstein-Barr virus infection",{"$nulls":3},"GO:0016605///PML body+++GO:0000785///chromatin+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0016363///nuclear matrix+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0005521///lamin binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0016301///kinase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0046872///metal ion binding+++GO:0042826///histone deacetylase binding+++GO:0005515///protein binding+++GO:0017151///DEAD/H-box RNA helicase binding","GO:0016310///phosphorylation+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0033127///regulation of histone phosphorylation+++GO:0031065///positive regulation of histone deacetylation+++GO:0010793///regulation of mRNA export from nucleus+++GO:0007076///mitotic chromosome condensation+++GO:0051081///nuclear envelope disassembly+++GO:0044839///cell cycle G2/M phase transition+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR034736///Zinc finger C2H2 AKAP95-type+++IPR007071///A-kinase anchoring protein 95 (AKAP95)","[AKP8L_HUMAN|Reviewed]RecName: Full=A-kinase anchor protein 8-like; Short=AKAP8-like protein; AltName: Full=Helicase A-binding protein 95; Short=HAP95; AltName: Full=Homologous to AKAP95 protein; Short=HA95; AltName: Full=Neighbor of A-kinase-anchoring protein 95; Short=Neighbor of AKAP95;+++[B3KMD4_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein 8-like, isoform CRA_d {ECO:0000313|EMBL:EAW84478.1}; SubName: Full=cDNA FLJ10732 fis, clone NT2RP3001384, highly similar to A-kinase anchor protein 8 {ECO:0000313|EMBL:BAG50946.1};+++[M0QYT7_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8-like {ECO:0000313|Ensembl:ENSP00000470067}; Flags: Fragment;+++[M0R008_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8-like {ECO:0000313|Ensembl:ENSP00000470906};+++[M0R010_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8-like {ECO:0000313|Ensembl:ENSP00000470912}; Flags: Fragment;+++[M0R1L5_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8-like {ECO:0000313|Ensembl:ENSP00000471958};+++[M0R1Y5_HUMAN|Unreviewed]SubName: Full=A-kinase anchor protein 8-like {ECO:0000313|Ensembl:ENSP00000472188}; Flags: Fragment;+++[V9GZ50_HUMAN|Unreviewed]SubName: Full=A kinase (PRKA) anchor protein 8-like, isoform CRA_c {ECO:0000313|EMBL:EAW84477.1}; SubName: Full=A-kinase anchor protein 8-like {ECO:0000313|Ensembl:ENSP00000477434};"]
[27037,"'TRMT2A'",709,654,681.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0070877///microprocessor complex+++GO:0005730///nucleolus","GO:0008173///RNA methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0003676///nucleic acid binding","GO:0001510///RNA methylation+++GO:0006396///RNA processing+++GO:0032259///methylation","IPR029063///S-adenosyl-L-methionine-dependent methyltransferase+++IPR034262///TRMT2A, RNA recognition motif+++IPR025714///Methyltransferase domain+++IPR035979///RNA-binding domain superfamily+++IPR010280///(Uracil-5)-methyltransferase family+++IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[TRM2A_HUMAN|Reviewed]RecName: Full=tRNA (uracil-5-)-methyltransferase homolog A; EC=2.1.1.-; AltName: Full=HpaII tiny fragments locus 9c protein;+++[C9K041_HUMAN|Unreviewed]SubName: Full=tRNA (uracil-5-)-methyltransferase homolog A {ECO:0000313|Ensembl:ENSP00000393911}; Flags: Fragment;+++[F2Z2W7_HUMAN|Unreviewed]SubName: Full=tRNA (uracil-5-)-methyltransferase homolog A {ECO:0000313|Ensembl:ENSP00000395738};+++[H7BZZ4_HUMAN|Unreviewed]SubName: Full=tRNA (uracil-5-)-methyltransferase homolog A {ECO:0000313|Ensembl:ENSP00000392261}; Flags: Fragment;+++[H7C100_HUMAN|Unreviewed]SubName: Full=tRNA (uracil-5-)-methyltransferase homolog A {ECO:0000313|Ensembl:ENSP00000397744}; Flags: Fragment;"]
[27076,"'LYPD3'",19,11,15,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0046658///anchored component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane","GO:0043236///laminin binding","GO:0007160///cell-matrix adhesion","IPR016054///Ly-6 antigen/uPA receptor-like","[LYPD3_HUMAN|Reviewed]RecName: Full=Ly6/PLAUR domain-containing protein 3; AltName: Full=GPI-anchored metastasis-associated protein C4.4A homolog; AltName: Full=Matrigel-induced gene C4 protein; Short=MIG-C4; Flags: Precursor;+++[B2RBR3_HUMAN|Unreviewed]SubName: Full=LY6/PLAUR domain containing 3 {ECO:0000313|EMBL:EAW57190.1}; SubName: Full=cDNA PSEC0157 fis, clone PLACE1008238, highly similar to Ly6/PLAUR domain-containing protein 3 {ECO:0000313|EMBL:BAG52146.1}; SubName: Full=cDNA, FLJ95643, Homo sapiens GPI-anchored metastasis-associated protein homolog(C4.4A), mRNA {ECO:0000313|EMBL:BAG37310.1};"]
[27101,"'CACYBP'",276,265,270.5,"04310///Wnt signaling pathway",null,"M00179///Ribosome, archaea+++M00178///Ribosome, bacteria",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0030877///beta-catenin destruction complex+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0031625///ubiquitin protein ligase binding+++GO:0015631///tubulin binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0044548///S100 protein binding","GO:0007507///heart development","IPR015120///Siah interacting protein, N-terminal+++IPR008978///HSP20-like chaperone+++IPR007699///SGS domain+++IPR007052///CS domain+++IPR037893///Calcyclin-binding Protein, CS domain+++IPR037201///Calcyclin-binding protein, N-terminal","[CYBP_HUMAN|Reviewed]RecName: Full=Calcyclin-binding protein; Short=CacyBP; Short=hCacyBP; AltName: Full=S100A6-binding protein; AltName: Full=Siah-interacting protein;+++[A0A024R904_HUMAN|Unreviewed]SubName: Full=Calcyclin binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW90983.1};+++[B2ZWH1_HUMAN|Unreviewed]SubName: Full=Calcyclin-binding protein {ECO:0000313|Ensembl:ENSP00000403674}; Flags: Fragment;+++[Q6NVY0_HUMAN|Unreviewed]SubName: Full=Calcyclin binding protein {ECO:0000313|EMBL:AAH67823.1};"]
[27130,"'INVS'",124,152,138,"04310///Wnt signaling pathway","H00537///Nephronophthisis",null,null,"GO:0005929///cilium+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005516///calmodulin binding","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0007275///multicellular organism development","IPR002110///Ankyrin repeat+++IPR000048///IQ motif, EF-hand binding site+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR020683///Ankyrin repeat-containing domain","[INVS_HUMAN|Reviewed]RecName: Full=Inversin; AltName: Full=Inversion of embryo turning homolog; AltName: Full=Nephrocystin-2;+++[A0A024R153_HUMAN|Unreviewed]SubName: Full=Inversin, isoform CRA_a {ECO:0000313|EMBL:EAW58925.1};+++[Q2M1I4_HUMAN|Unreviewed]SubName: Full=INVS protein {ECO:0000313|EMBL:AAI12352.1};"]
[27156,"'RSPH14'",1,5,3,"04730///Long-term depression",{"$nulls":3},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","IPR000225///Armadillo+++IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical","[RSP14_HUMAN|Reviewed]RecName: Full=Radial spoke head 14 homolog; AltName: Full=Rhabdoid tumor deletion region protein 1;+++[B5MCI8_HUMAN|Unreviewed]SubName: Full=Radial spoke head 14 homolog {ECO:0000313|Ensembl:ENSP00000385567};+++[H7BZU8_HUMAN|Unreviewed]SubName: Full=Radial spoke head 14 homolog {ECO:0000313|Ensembl:ENSP00000391552}; Flags: Fragment;+++[H7C2M5_HUMAN|Unreviewed]SubName: Full=Radial spoke head 14 homolog {ECO:0000313|Ensembl:ENSP00000406822}; Flags: Fragment;+++[H7C3W6_HUMAN|Unreviewed]SubName: Full=Radial spoke head 14 homolog {ECO:0000313|Ensembl:ENSP00000414155}; Flags: Fragment;"]
[27190,"'IL17B'",2,0,1,"04060///Cytokine-cytokine receptor interaction+++04657///IL-17 signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0005125///cytokine activity","GO:0006955///immune response+++GO:1900017///positive regulation of cytokine production involved in inflammatory response+++GO:0007267///cell-cell signaling+++GO:0006954///inflammatory response+++GO:0010469///regulation of signaling receptor activity","IPR010345///Interleukin-17 family+++IPR020440///Interleukin-17, chordata+++IPR029034///Cystine-knot cytokine","[IL17B_HUMAN|Reviewed]RecName: Full=Interleukin-17B; Short=IL-17B; AltName: Full=Cytokine Zcyto7; AltName: Full=Interleukin-20; Short=IL-20; AltName: Full=Neuronal interleukin-17-related factor; Flags: Precursor;+++[Q6IAG3_HUMAN|Unreviewed]SubName: Full=IL17B protein {ECO:0000313|EMBL:CAG33473.1};"]
[27241,"'BBS9'",138,125,131.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00418///Bardet-Biedl syndrome (BBS)",null,null,"GO:0035869///ciliary transition zone+++GO:0034464///BBSome+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0005829///cytosol+++GO:0034451///centriolar satellite+++GO:0005856///cytoskeleton+++GO:0000242///pericentriolar material+++GO:0060170///ciliary membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0045444///fat cell differentiation+++GO:0060271///cilium assembly+++GO:0050896///response to stimulus+++GO:0030030///cell projection organization+++GO:0015031///protein transport+++GO:0007601///visual perception+++GO:0061512///protein localization to cilium","IPR028073///PTHB1, N-terminal domain+++IPR026511///Parathyroid hormone-responsive B1+++IPR028074///PTHB1, C-terminal domain","[PTHB1_HUMAN|Reviewed]RecName: Full=Protein PTHB1; AltName: Full=Bardet-Biedl syndrome 9 protein; AltName: Full=Parathyroid hormone-responsive B1 gene protein;+++[A0A090N7W2_HUMAN|Unreviewed]SubName: Full=Parathyroid hormone-responsive B1 protein {ECO:0000313|EMBL:EAL24467.1}; SubName: Full=Parathyroid hormone-responsive B1, isoform CRA_c {ECO:0000313|EMBL:EAW94017.1};+++[A0A090N8P4_HUMAN|Unreviewed]SubName: Full=Parathyroid hormone-responsive B1 protein {ECO:0000313|EMBL:EAL24466.1};+++[A0A0D9SEP0_HUMAN|Unreviewed]SubName: Full=Protein PTHB1 {ECO:0000313|Ensembl:ENSP00000485871}; Flags: Fragment;+++[C9JJ08_HUMAN|Unreviewed]SubName: Full=Protein PTHB1 {ECO:0000313|Ensembl:ENSP00000415794}; Flags: Fragment;+++[C9JRR5_HUMAN|Unreviewed]SubName: Full=Protein PTHB1 {ECO:0000313|Ensembl:ENSP00000388646}; Flags: Fragment;+++[F8WCG5_HUMAN|Unreviewed]SubName: Full=Protein PTHB1 {ECO:0000313|Ensembl:ENSP00000412159};+++[H7BZ69_HUMAN|Unreviewed]SubName: Full=Protein PTHB1 {ECO:0000313|Ensembl:ENSP00000388114}; Flags: Fragment;"]
[27258,"'LSM3'",397,387,392,"03040///Spliceosome+++03018///RNA degradation",null,"M00397///Lsm 1-7 complex+++M00354///Spliceosome, U4/U6.U5 tri-snRNP+++M00396///Lsm 2-8 complex",null,"GO:0005681///spliceosomal complex+++GO:0120115///Lsm2-8 complex+++GO:1990726///Lsm1-7-Pat1 complex+++GO:0005829///cytosol+++GO:0071005///U2-type precatalytic spliceosome+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0000932///P-body+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005688///U6 snRNP","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0033962///cytoplasmic mRNA processing body assembly+++GO:0008380///RNA splicing","IPR010920///LSM domain superfamily+++IPR040002///U6 snRNA-associated Sm-like protein Lsm3+++IPR034105///Sm-like protein Lsm3+++IPR001163///LSM domain, eukaryotic/archaea-type","[LSM3_HUMAN|Reviewed]RecName: Full=U6 snRNA-associated Sm-like protein LSm3;+++[B2R5H5_HUMAN|Unreviewed]RecName: Full=U6 snRNA-associated Sm-like protein LSm3 {ECO:0000256|RuleBase:RU365046};"]
[27304,"'MOCS3'",138.98,167.78,153.38,"04122///Sulfur relay system",null,null,"R07459///ATP:[sulfur-carrier protein] adenylyltransferase   Sulfur-carrier protein + ATP <=> Adenylyl-[sulfur-carrier protein] + Diphosphate+++R07461///[enzyme]-S-sulfanyl-L-cysteine:adenylyl-[sulfur-carrier protein] sulfurtransferase   [Enzyme]-S-sulfanylcysteine + Adenylyl-[sulfur-carrier protein] + Reduced acceptor <=> AMP + Thiocarboxy-[sulfur-carrier protein] + [Enzyme]-cysteine + Acceptor","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0008641///ubiquitin-like modifier activating enzyme activity+++GO:0000166///nucleotide binding+++GO:0042292///URM1 activating enzyme activity+++GO:0005524///ATP binding+++GO:0004792///thiosulfate sulfurtransferase activity+++GO:0016783///sulfurtransferase activity+++GO:0016740///transferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding+++GO:0061604///molybdopterin-synthase sulfurtransferase activity+++GO:0003824///catalytic activity+++GO:0061605///molybdopterin-synthase adenylyltransferase activity","GO:0002098///tRNA wobble uridine modification+++GO:0006777///Mo-molybdopterin cofactor biosynthetic process+++GO:0008033///tRNA processing+++GO:0008152///metabolic process+++GO:0002143///tRNA wobble position uridine thiolation+++GO:0034227///tRNA thio-modification+++GO:0018192///enzyme active site formation via cysteine modification to L-cysteine persulfide+++GO:0032324///molybdopterin cofactor biosynthetic process+++GO:0032447///protein urmylation","IPR028885///Adenylyltransferase and sulfurtransferase MOCS3/Uba4+++IPR001763///Rhodanese-like domain+++IPR036873///Rhodanese-like domain superfamily+++IPR035985///Ubiquitin-activating enzyme+++IPR000594///THIF-type NAD/FAD binding fold","[MOCS3_HUMAN|Reviewed]RecName: Full=Adenylyltransferase and sulfurtransferase MOCS3 {ECO:0000255|HAMAP-Rule:MF_03049}; AltName: Full=Molybdenum cofactor synthesis protein 3 {ECO:0000255|HAMAP-Rule:MF_03049}; AltName: Full=Molybdopterin synthase sulfurylase; Short=MPT synthase sulfurylase; Includes: RecName: Full=Molybdopterin-synthase adenylyltransferase {ECO:0000255|HAMAP-Rule:MF_03049}; EC=2.7.7.80 {ECO:0000255|HAMAP-Rule:MF_03049, ECO:0000269|PubMed:15073332, ECO:0000269|PubMed:17459099, ECO:0000269|PubMed:18650437}; AltName: Full=Adenylyltransferase MOCS3 {ECO:0000255|HAMAP-Rule:MF_03049}; AltName: Full=Sulfur carrier protein MOCS2A adenylyltransferase {ECO:0000255|HAMAP-Rule:MF_03049}; Includes: RecName: Full=Molybdopterin-synthase sulfurtransferase {ECO:0000255|HAMAP-Rule:MF_03049}; EC=2.8.1.11 {ECO:0000255|HAMAP-Rule:MF_03049, ECO:0000269|PubMed:15073332, ECO:0000269|PubMed:17459099, ECO:0000269|PubMed:18650437}; AltName: Full=Sulfur carrier protein MOCS2A sulfurtransferase {ECO:0000255|HAMAP-Rule:MF_03049}; AltName: Full=Sulfurtransferase MOCS3 {ECO:0000255|HAMAP-Rule:MF_03049};"]
[27335,"'EIF3K'",1588,1120,1354,{"$nulls":4},"GO:0005829///cytosol+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0016282///eukaryotic 43S preinitiation complex","GO:0005515///protein binding+++GO:0003743///translation initiation factor activity+++GO:0043022///ribosome binding+++GO:0003723///RNA binding","GO:0006413///translational initiation+++GO:0006412///translation+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002183///cytoplasmic translational initiation+++GO:0006446///regulation of translational initiation","IPR009374///Eukaryotic translation initiation factor 3 subunit K+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR000717///Proteasome component (PCI) domain+++IPR016020///Translation initiation factor 3, subunit 12, N-terminal, eukaryotic+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR016024///Armadillo-type fold+++IPR033464///CSN8/PSMD8/EIF3K","[EIF3K_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000255|HAMAP-Rule:MF_03010}; Short=eIF3k {ECO:0000255|HAMAP-Rule:MF_03010}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000255|HAMAP-Rule:MF_03010}; AltName: Full=Muscle-specific gene M9 protein; AltName: Full=PLAC-24; AltName: Full=eIF-3 p25 {ECO:0000255|HAMAP-Rule:MF_03010}; AltName: Full=eIF-3 p28;+++[A0A087WVB9_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000256|HAMAP-Rule:MF_03010}; Short=eIF3k {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=eIF-3 p25 {ECO:0000256|HAMAP-Rule:MF_03010};+++[B4DQ48_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000313|Ensembl:ENSP00000440999}; SubName: Full=cDNA FLJ55131, highly similar to Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000313|EMBL:BAG60810.1};+++[B4DVD7_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000256|HAMAP-Rule:MF_03010}; Short=eIF3k {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=eIF-3 p25 {ECO:0000256|HAMAP-Rule:MF_03010};+++[K7EK53_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000313|Ensembl:ENSP00000465460};+++[K7EQM4_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000313|Ensembl:ENSP00000467895}; Flags: Fragment;+++[K7ERF1_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000256|HAMAP-Rule:MF_03010}; Short=eIF3k {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=eIF-3 p25 {ECO:0000256|HAMAP-Rule:MF_03010};+++[K7ES31_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000313|Ensembl:ENSP00000468525};+++[U3LUI4_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit K {ECO:0000256|HAMAP-Rule:MF_03010}; Short=eIF3k {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 12 {ECO:0000256|HAMAP-Rule:MF_03010}; AltName: Full=eIF-3 p25 {ECO:0000256|HAMAP-Rule:MF_03010};"]
[2735,"'GLI1'",4,12,8,"04340///Hedgehog signaling pathway+++05217///Basal cell carcinoma+++04024///cAMP signaling pathway+++05200///Pathways in cancer",null,"M00678///Hedgehog signaling",null,"GO:0005930///axoneme+++GO:0005929///cilium+++GO:0005654///nucleoplasm+++GO:0097546///ciliary base+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0097542///ciliary tip","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0008017///microtubule binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding","GO:0030154///cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0045667///regulation of osteoblast differentiation+++GO:0021938///smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation+++GO:0001649///osteoblast differentiation+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:0045880///positive regulation of smoothened signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0030324///lung development+++GO:0008284///positive regulation of cell proliferation+++GO:0009611///response to wounding+++GO:0048546///digestive tract morphogenesis+++GO:0097421///liver regeneration+++GO:0060070///canonical Wnt signaling pathway+++GO:0007224///smoothened signaling pathway+++GO:0008589///regulation of smoothened signaling pathway+++GO:0007283///spermatogenesis+++GO:0009954///proximal/distal pattern formation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045740///positive regulation of DNA replication+++GO:0007418///ventral midline development+++GO:0030850///prostate gland development+++GO:0021983///pituitary gland development+++GO:0030335///positive regulation of cell migration+++GO:0009913///epidermal cell differentiation+++GO:2000345///regulation of hepatocyte proliferation+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060032///notochord regression+++GO:0021696///cerebellar cortex morphogenesis+++GO:0009953///dorsal/ventral pattern formation","IPR036236///Zinc finger C2H2 superfamily+++IPR032850///Zinc finger protein GLI1+++IPR013087///Zinc finger C2H2-type","[GLI1_HUMAN|Reviewed]RecName: Full=Zinc finger protein GLI1; AltName: Full=Glioma-associated oncogene; AltName: Full=Oncogene GLI;+++[B1Q2M2_HUMAN|Unreviewed]SubName: Full=Glioma-associated oncogene 1 {ECO:0000313|EMBL:BAG16751.1}; Flags: Fragment;+++[B4DNF7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57539, highly similar to Zinc finger protein GLI1 {ECO:0000313|EMBL:BAG60219.1};+++[E9PIB9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein GLI1 {ECO:0000313|Ensembl:ENSP00000436671}; Flags: Fragment;+++[E9PQQ1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein GLI1 {ECO:0000313|Ensembl:ENSP00000434421}; Flags: Fragment;+++[T2HQN2_HUMAN|Unreviewed]SubName: Full=GLI-Kruppel family member GLI1 splice variant {ECO:0000313|EMBL:BAN82437.1}; Flags: Fragment;"]
[27350,"'APOBEC3C'",1493.07,1288.79,1390.93,{"$nulls":4},"GO:0005634///nucleus+++GO:0000932///P-body+++GO:0005737///cytoplasm","GO:0003824///catalytic activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0004126///cytidine deaminase activity+++GO:0046872///metal ion binding","GO:0010529///negative regulation of transposition+++GO:0045087///innate immune response+++GO:0016032///viral process+++GO:0045869///negative regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:0002376///immune system process+++GO:0070383///DNA cytosine deamination+++GO:0009972///cytidine deamination+++GO:0051607///defense response to virus+++GO:0016554///cytidine to uridine editing+++GO:0080111///DNA demethylation+++GO:0045071///negative regulation of viral genome replication","IPR016192///APOBEC/CMP deaminase, zinc-binding+++IPR016193///Cytidine deaminase-like+++IPR013158///APOBEC-like, N-terminal+++IPR002125///Cytidine and deoxycytidylate deaminase domain","[ABC3C_HUMAN|Reviewed]RecName: Full=DNA dC->dU-editing enzyme APOBEC-3C; Short=A3C; EC=3.5.4.-; AltName: Full=APOBEC1-like; AltName: Full=Phorbolin I;+++[F8WB92_HUMAN|Unreviewed]SubName: Full=DNA dC->dU-editing enzyme APOBEC-3C {ECO:0000313|Ensembl:ENSP00000390855};+++[M4VP52_HUMAN|Unreviewed]SubName: Full=Apolipoprotein B editing enzyme catalytic polypeptide-like 3C {ECO:0000313|EMBL:AGI04216.1};"]
[2744,"'GLS'",1110,1721,1415.5,"00250///Alanine, aspartate and glutamate metabolism+++01100///Metabolic pathways+++00471///D-Glutamine and D-glutamate metabolism+++04964///Proximal tubule bicarbonate reclamation+++00220///Arginine biosynthesis+++05230///Central carbon metabolism in cancer+++05206///MicroRNAs in cancer+++04727///GABAergic synapse+++04724///Glutamatergic synapse","H00363///Candidiasis+++H00089///IFN-gamma/IL-12 axis+++H01109///Chronic mucocutaneous candidiasis (CMC)","M00684///JAK-STAT signaling","R00256///L-glutamine amidohydrolase   L-Glutamine + H2O <=> L-Glutamate + Ammonia+++R01579///D-Glutamine amidohydrolase   D-Glutamine + H2O <=> D-Glutamate + Ammonia","GO:0030424///axon+++GO:0048471///perinuclear region of cytoplasm+++GO:0005730///nucleolus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0030425///dendrite+++GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0032991///protein-containing complex","GO:0042802///identical protein binding+++GO:0070491///repressing transcription factor binding+++GO:0042393///histone binding+++GO:0035257///nuclear hormone receptor binding+++GO:0051721///protein phosphatase 2A binding+++GO:1990841///promoter-specific chromatin binding+++GO:0000982///transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0031730///CCR5 chemokine receptor binding+++GO:0000983///transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0019899///enzyme binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0004359///glutaminase activity+++GO:0003690///double-stranded DNA binding+++GO:0042803///protein homodimerization activity+++GO:0035035///histone acetyltransferase binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0045296///cadherin binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0060337///type I interferon signaling pathway+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0042542///response to hydrogen peroxide+++GO:0016032///viral process+++GO:0070106///interleukin-27-mediated signaling pathway+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0035456///response to interferon-beta+++GO:0070102///interleukin-6-mediated signaling pathway+++GO:0007268///chemical synaptic transmission+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0060334///regulation of interferon-gamma-mediated signaling pathway+++GO:0038114///interleukin-21-mediated signaling pathway+++GO:0006537///glutamate biosynthetic process+++GO:0051289///protein homotetramerization+++GO:0007259///JAK-STAT cascade+++GO:0034097///response to cytokine+++GO:0014047///glutamate secretion+++GO:0032727///positive regulation of interferon-alpha production+++GO:0051607///defense response to virus+++GO:0051591///response to cAMP+++GO:0001967///suckling behavior+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0002087///regulation of respiratory gaseous exchange by neurological system process+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0007584///response to nutrient+++GO:0071407///cellular response to organic cyclic compound+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0072308///negative regulation of metanephric nephron tubule epithelial cell differentiation+++GO:0010742///macrophage derived foam cell differentiation+++GO:0003340///negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis+++GO:0051770///positive regulation of nitric-oxide synthase biosynthetic process+++GO:0008015///blood circulation+++GO:0043434///response to peptide hormone+++GO:0006355///regulation of transcription, DNA-templated+++GO:0032869///cellular response to insulin stimulus+++GO:0016525///negative regulation of angiogenesis+++GO:0006351///transcription, DNA-templated+++GO:0002230///positive regulation of defense response to virus by host+++GO:0042981///regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0009612///response to mechanical stimulus+++GO:0008652///cellular amino acid biosynthetic process+++GO:0070757///interleukin-35-mediated signaling pathway+++GO:0006543///glutamine catabolic process+++GO:0035458///cellular response to interferon-beta+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0072136///metanephric mesenchymal cell proliferation involved in metanephros development+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:0038113///interleukin-9-mediated signaling pathway+++GO:0071346///cellular response to interferon-gamma+++GO:0046725///negative regulation by virus of viral protein levels in host cell+++GO:0061326///renal tubule development","IPR015868///Glutaminase+++IPR002110///Ankyrin repeat+++IPR012338///Beta-lactamase/transpeptidase-like+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily","[GLSK_HUMAN|Reviewed]RecName: Full=Glutaminase kidney isoform, mitochondrial; Short=GLS; EC=3.5.1.2; AltName: Full=K-glutaminase; AltName: Full=L-glutamine amidohydrolase; Flags: Precursor;+++[Q68D38_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686O15119 {ECO:0000313|EMBL:CAH18392.1}; Flags: Fragment;"]
[2770,"'GNAI1'",296,270,283,"04015///Rap1 signaling pathway+++04915///Estrogen signaling pathway+++05030///Cocaine addiction+++04934///Cushing's syndrome+++04728///Dopaminergic synapse+++04540///Gap junction+++04022///cGMP-PKG signaling pathway+++04923///Regulation of lipolysis in adipocytes+++05133///Pertussis+++04924///Renin secretion+++04360///Axon guidance+++05034///Alcoholism+++04921///Oxytocin signaling pathway+++05142///Chagas disease (American trypanosomiasis)+++04727///GABAergic synapse+++04730///Long-term depression+++05163///Human cytomegalovirus infection+++04713///Circadian entrainment+++04726///Serotonergic synapse+++04611///Platelet activation+++04926///Relaxin signaling pathway+++05145///Toxoplasmosis+++04725///Cholinergic synapse+++05012///Parkinson's disease+++04071///Sphingolipid signaling pathway+++04723///Retrograde endocannabinoid signaling+++04024///cAMP signaling pathway+++04971///Gastric acid secretion+++04371///Apelin signaling pathway+++04914///Progesterone-mediated oocyte maturation+++04928///Parathyroid hormone synthesis, secretion and action+++04062///Chemokine signaling pathway+++04670///Leukocyte transendothelial migration+++04261///Adrenergic signaling in cardiomyocytes+++04724///Glutamatergic synapse+++05032///Morphine addiction+++05200///Pathways in cancer+++04916///Melanogenesis","H00033///Adrenal carcinoma+++H01019///Catecholaminergic polymorphic ventricular tachycardia+++H01884///Auriculocondylar syndrome","M00695///cAMP signaling",null,"GO:0099738///cell cortex region+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005765///lysosomal membrane+++GO:0070062///extracellular exosome+++GO:0005834///heterotrimeric G-protein complex+++GO:0030496///midbody+++GO:0005938///cell cortex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005815///microtubule organizing center","GO:0019003///GDP binding+++GO:0031683///G-protein beta/gamma-subunit complex binding+++GO:0005515///protein binding+++GO:0000287///magnesium ion binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0031821///G protein-coupled serotonin receptor binding+++GO:0046872///metal ion binding+++GO:0001664///G protein-coupled receptor binding+++GO:0019001///guanyl nucleotide binding+++GO:0005525///GTP binding","GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007193///adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway+++GO:0007049///cell cycle+++GO:0043434///response to peptide hormone+++GO:0007165///signal transduction+++GO:1904322///cellular response to forskolin+++GO:0006457///protein folding+++GO:1904778///positive regulation of protein localization to cell cortex+++GO:0043949///regulation of cAMP-mediated signaling+++GO:0051301///cell division+++GO:0060236///regulation of mitotic spindle organization","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR011025///G protein alpha subunit, helical insertion+++IPR001019///Guanine nucleotide binding protein (G-protein), alpha subunit+++IPR001408///G-protein alpha subunit, group I","[GNAI1_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein G(i) subunit alpha-1; AltName: Full=Adenylate cyclase-inhibiting G alpha protein;+++[C9J2Z2_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(i) subunit alpha-1 {ECO:0000313|Ensembl:ENSP00000391439}; Flags: Fragment;+++[C9JL77_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(i) subunit alpha-1 {ECO:0000313|Ensembl:ENSP00000388347}; Flags: Fragment;+++[C9JPP4_HUMAN|Unreviewed]SubName: Full=Guanine nucleotide-binding protein G(i) subunit alpha-1 {ECO:0000313|Ensembl:ENSP00000389435}; Flags: Fragment;+++[O43383_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein GNAI1 {ECO:0000313|EMBL:AAC03418.1}; Flags: Fragment;"]
[2791,"'GNG11'",73,93,83,"04926///Relaxin signaling pathway+++05034///Alcoholism+++04062///Chemokine signaling pathway+++05163///Human cytomegalovirus infection+++04725///Cholinergic synapse+++04727///GABAergic synapse+++04151///PI3K-Akt signaling pathway+++05032///Morphine addiction+++04728///Dopaminergic synapse+++04713///Circadian entrainment+++04014///Ras signaling pathway+++04371///Apelin signaling pathway+++05200///Pathways in cancer+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04724///Glutamatergic synapse+++04723///Retrograde endocannabinoid signaling+++04726///Serotonergic synapse",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005834///heterotrimeric G-protein complex","GO:0005515///protein binding+++GO:0003924///GTPase activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","IPR001770///G-protein, gamma subunit+++IPR015898///G-protein gamma-like domain+++IPR036284///G-protein gamma-like domain superfamily","[GBG11_HUMAN|Reviewed]RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11; Flags: Precursor;+++[Q53Y01_HUMAN|Unreviewed]RecName: Full=Guanine nucleotide-binding protein subunit gamma {ECO:0000256|RuleBase:RU004973};"]
[280636,"'SELENOH'",626,378,502,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus","GO:0003723///RNA binding",null,"IPR011893///Selenoprotein, Rdx-type+++IPR036249///Thioredoxin-like superfamily","[SELH_HUMAN|Reviewed]RecName: Full=Selenoprotein H {ECO:0000305}; Short=SelH;+++[A0A024R4Y9_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 31 {ECO:0000313|EMBL:EAW73782.1};+++[A0A087WYP2_HUMAN|Unreviewed]SubName: Full=Selenoprotein H {ECO:0000313|Ensembl:ENSP00000481984};+++[H0YE28_HUMAN|Unreviewed]SubName: Full=Selenoprotein H {ECO:0000313|Ensembl:ENSP00000434875}; Flags: Fragment;"]
[2825,"'GPR1'",86,75,80.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0043231///intracellular membrane-bounded organelle","GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0042923///neuropeptide binding","GO:0007218///neuropeptide signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR002275///G protein-coupled receptor 1 orphan+++IPR017452///GPCR, rhodopsin-like, 7TM","[GPR1_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor 1;+++[C9J456_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 1 {ECO:0000313|Ensembl:ENSP00000391146}; Flags: Fragment;+++[C9JCK1_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 1 {ECO:0000313|Ensembl:ENSP00000404861}; Flags: Fragment;+++[C9JFR8_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 1 {ECO:0000313|Ensembl:ENSP00000416474}; Flags: Fragment;+++[C9JKF3_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 1 {ECO:0000313|Ensembl:ENSP00000414524}; Flags: Fragment;+++[C9JQB7_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 1 {ECO:0000313|Ensembl:ENSP00000414836}; Flags: Fragment;+++[C9JSU0_HUMAN|Unreviewed]SubName: Full=G-protein-coupled receptor 1 {ECO:0000313|Ensembl:ENSP00000409577}; Flags: Fragment;"]
[283,"'ANG'",50.34,41.72,46.03,null,"H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0032311///angiogenin-PRI complex+++GO:0005634///nucleus+++GO:0031410///cytoplasmic vesicle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005604///basement membrane+++GO:0030426///growth cone+++GO:0005730///nucleolus+++GO:0043025///neuronal cell body","GO:0019843///rRNA binding+++GO:0005102///signaling receptor binding+++GO:0042803///protein homodimerization activity+++GO:0005507///copper ion binding+++GO:0016787///hydrolase activity+++GO:0042277///peptide binding+++GO:0004518///nuclease activity+++GO:0003677///DNA binding+++GO:0003779///actin binding+++GO:0008201///heparin binding+++GO:0004522///ribonuclease A activity+++GO:0004540///ribonuclease activity+++GO:0004519///endonuclease activity+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0001541///ovarian follicle development+++GO:0042327///positive regulation of phosphorylation+++GO:0030154///cell differentiation+++GO:0006651///diacylglycerol biosynthetic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0007275///multicellular organism development+++GO:0007154///cell communication+++GO:0001890///placenta development+++GO:0042592///homeostatic process+++GO:0016477///cell migration+++GO:0006379///mRNA cleavage+++GO:0001666///response to hypoxia+++GO:0050714///positive regulation of protein secretion+++GO:0045087///innate immune response+++GO:0001556///oocyte maturation+++GO:0032148///activation of protein kinase B activity+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0009725///response to hormone+++GO:0034332///adherens junction organization+++GO:0032431///activation of phospholipase A2 activity+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0017148///negative regulation of translation+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0009303///rRNA transcription+++GO:0001525///angiogenesis+++GO:0030041///actin filament polymerization+++GO:0007202///activation of phospholipase C activity","IPR023411///Ribonuclease A, active site+++IPR036816///Ribonuclease A-like domain superfamily+++IPR001427///Pancreatic ribonuclease+++IPR023412///Ribonuclease A-domain","[ANGI_HUMAN|Reviewed]RecName: Full=Angiogenin; EC=3.1.27.-; AltName: Full=Ribonuclease 5; Short=RNase 5; Flags: Precursor;+++[W0UV28_HUMAN|Unreviewed]SubName: Full=Ribonuclease A A1 {ECO:0000313|EMBL:CDG31911.1};"]
[283234,"'CCDC88B'",25,36,30.5,"04010///MAPK signaling pathway+++04668///TNF signaling pathway",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005813///centrosome","GO:0051959///dynein light intermediate chain binding+++GO:0008017///microtubule binding","GO:0001819///positive regulation of cytokine production+++GO:0050870///positive regulation of T cell activation+++GO:0030705///cytoskeleton-dependent intracellular transport+++GO:0042102///positive regulation of T cell proliferation+++GO:0042832///defense response to protozoan+++GO:0031122///cytoplasmic microtubule organization","IPR036872///CH domain superfamily+++IPR008636///Hook-like protein family","[CC88B_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 88B; AltName: Full=Brain leucine zipper domain-containing protein; AltName: Full=Gipie {ECO:0000303|PubMed:21289099}; AltName: Full=Hook-related protein 3 {ECO:0000303|PubMed:25762780}; Short=HkRP3;+++[B2RTU8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain containing 88B {ECO:0000313|EMBL:AAI40823.1};+++[H7BY33_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 88B {ECO:0000313|Ensembl:ENSP00000352974};"]
[283417,"'DPY19L2'",24,48.85,36.425,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus","GO:0000030///mannosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0016740///transferase activity","GO:0007275///multicellular organism development+++GO:0007286///spermatid development+++GO:0030154///cell differentiation+++GO:0007283///spermatogenesis+++GO:0018406///protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan","IPR030042///Probable C-mannosyltransferase DPY19L2+++IPR018732///Dpy-19/Dpy-19-like","[D19L2_HUMAN|Reviewed]RecName: Full=Probable C-mannosyltransferase DPY19L2; EC=2.4.1.-; AltName: Full=Dpy-19-like protein 2; AltName: Full=Protein dpy-19 homolog 2;+++[F5H0W1_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L2 {ECO:0000313|Ensembl:ENSP00000445878};+++[F5H1L7_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L2 {ECO:0000313|Ensembl:ENSP00000439567}; Flags: Fragment;+++[F5H4G6_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L2 {ECO:0000313|Ensembl:ENSP00000444932}; Flags: Fragment;+++[F5H5T7_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L2 {ECO:0000313|Ensembl:ENSP00000443126}; Flags: Fragment;+++[H0YF77_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L2 {ECO:0000313|Ensembl:ENSP00000437474}; Flags: Fragment;"]
[283576,"'ZDHHC22'",1,2.65,1.825,{"$nulls":4},"GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0016746///transferase activity, transferring acyl groups+++GO:0005515///protein binding+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0016740///transferase activity","GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0006612///protein targeting to membrane+++GO:0072659///protein localization to plasma membrane+++GO:0018345///protein palmitoylation","IPR000731///Sterol-sensing domain+++IPR001594///Palmitoyltransferase, DHHC domain","[ZDH22_HUMAN|Reviewed]RecName: Full=Palmitoyltransferase ZDHHC22; EC=2.3.1.225 {ECO:0000269|PubMed:22399288}; AltName: Full=Zinc finger DHHC domain-containing protein 22; Short=DHHC-22; Short=zDHHC22;+++[G3V259_HUMAN|Unreviewed]SubName: Full=Palmitoyltransferase ZDHHC22 {ECO:0000313|Ensembl:ENSP00000450478}; Flags: Fragment;+++[G3V3N3_HUMAN|Unreviewed]SubName: Full=Palmitoyltransferase ZDHHC22 {ECO:0000313|Ensembl:ENSP00000451337}; Flags: Fragment;"]
[283820,"'NOMO2'",4278.22,5837.9,5058.06,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0032991///protein-containing complex","GO:0030246///carbohydrate binding+++GO:0005515///protein binding",null,"IPR013784///Carbohydrate-binding-like fold+++IPR008969///Carboxypeptidase-like, regulatory domain superfamily","[NOMO2_HUMAN|Reviewed]RecName: Full=Nodal modulator 2; AltName: Full=pM5 protein 2; Flags: Precursor;+++[A0A087WTD5_HUMAN|Unreviewed]SubName: Full=Nodal modulator 2 {ECO:0000313|Ensembl:ENSP00000477774};+++[H3BMJ6_HUMAN|Unreviewed]SubName: Full=Nodal modulator 2 {ECO:0000313|Ensembl:ENSP00000454412};+++[H3BNC4_HUMAN|Unreviewed]SubName: Full=Nodal modulator 2 {ECO:0000313|Ensembl:ENSP00000454780}; Flags: Fragment;+++[H3BPS9_HUMAN|Unreviewed]SubName: Full=Nodal modulator 2 {ECO:0000313|Ensembl:ENSP00000455456}; Flags: Fragment;+++[H3BTW1_HUMAN|Unreviewed]SubName: Full=Nodal modulator 2 {ECO:0000313|Ensembl:ENSP00000457351};"]
[283991,"'UBALD2'",769,626,697.5,{"$nulls":7},"IPR009060///UBA-like superfamily+++IPR039310///UBA-like domain-containing protein 1/2","[UBAD2_HUMAN|Reviewed]RecName: Full=UBA-like domain-containing protein 2;+++[K7EMI7_HUMAN|Unreviewed]SubName: Full=UBA-like domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000466518};+++[K7ERK7_HUMAN|Unreviewed]SubName: Full=UBA-like domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000468297}; Flags: Fragment;"]
[2841,"'GPR18'",2,0,1,{"$nulls":4},"GO:0030659///cytoplasmic vesicle membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0004930///G protein-coupled receptor activity","GO:0035025///positive regulation of Rho protein signal transduction+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0002300///CD8-positive, alpha-beta intraepithelial T cell differentiation+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0051482///positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway+++GO:0002689///negative regulation of leukocyte chemotaxis+++GO:0002305///CD8-positive, gamma-delta intraepithelial T cell differentiation","IPR028335///G protein-coupled receptor 18 orphan+++IPR017452///GPCR, rhodopsin-like, 7TM+++IPR000276///G protein-coupled receptor, rhodopsin-like","[GPR18_HUMAN|Reviewed]RecName: Full=N-arachidonyl glycine receptor; Short=NAGly receptor; AltName: Full=G-protein coupled receptor 18;+++[H9NIM1_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 18 {ECO:0000313|EMBL:AFF59486.1}; SubName: Full=HCG1644110 {ECO:0000313|EMBL:EAX09017.1};+++[Q5JUH9_HUMAN|Unreviewed]SubName: Full=N-arachidonyl glycine receptor {ECO:0000313|Ensembl:ENSP00000401611}; Flags: Fragment;"]
[284274,"'SMIM21'",1,0,0.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",{"$nulls":3},"[SMI21_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 21;+++[J3KSN8_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 21 {ECO:0000313|Ensembl:ENSP00000462572};+++[J9JIF2_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 21 {ECO:0000313|Ensembl:ENSP00000372083};"]
[284358,"'MAMSTR'",9,16,12.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0001085///RNA polymerase II transcription factor binding","GO:0010831///positive regulation of myotube differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR003034///SAP domain+++IPR036361///SAP domain superfamily","[MASTR_HUMAN|Reviewed]RecName: Full=MEF2-activating motif and SAP domain-containing transcriptional regulator; AltName: Full=MEF2-activating SAP transcriptional regulatory protein;+++[M0QXF1_HUMAN|Unreviewed]SubName: Full=MEF2-activating motif and SAP domain-containing transcriptional regulator {ECO:0000313|Ensembl:ENSP00000469127}; Flags: Fragment;+++[M0QY28_HUMAN|Unreviewed]SubName: Full=MEF2-activating motif and SAP domain-containing transcriptional regulator {ECO:0000313|Ensembl:ENSP00000469544}; Flags: Fragment;"]
[284451,"'ODF3L2'",8,6,7,{"$nulls":4},"GO:0005881///cytoplasmic microtubule",null,null,"IPR010736///Sperm-tail PG-rich repeat","[OD3L2_HUMAN|Reviewed]RecName: Full=Outer dense fiber protein 3-like protein 2;"]
[284759,"'SIRPB2'",2,7,4.5,{"$nulls":4},"GO:0016021///integral component of membrane",null,null,"IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013106///Immunoglobulin V-set domain+++IPR013783///Immunoglobulin-like fold+++IPR003598///Immunoglobulin subtype 2+++IPR003599///Immunoglobulin subtype","[SIRB2_HUMAN|Reviewed]RecName: Full=Signal-regulatory protein beta-2; Short=SIRP-beta-2; AltName: Full=Protein tyrosine phosphatase non-receptor type substrate 1-like 3; AltName: Full=Protein tyrosine phosphatase non-receptor type substrate protein; Flags: Precursor;+++[B3KTG0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ38180 fis, clone FCBBF1000121, weakly similar to Homo sapiens SHPS-1 {ECO:0000313|EMBL:BAG53072.1};+++[F2Z2Y9_HUMAN|Unreviewed]SubName: Full=Signal-regulatory protein beta-2 {ECO:0000313|Ensembl:ENSP00000432656};+++[V9GYW8_HUMAN|Unreviewed]SubName: Full=Signal-regulatory protein beta-2 {ECO:0000313|Ensembl:ENSP00000477149};"]
[285172,"'FAM126B'",81.97,105.92,93.945,null,"H00679///Hypomyelinating leukodystrophy",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005622///intracellular","GO:0005515///protein binding","GO:0072659///protein localization to plasma membrane+++GO:0046854///phosphatidylinositol phosphorylation","IPR018619///Hyccin","[F126B_HUMAN|Reviewed]RecName: Full=Protein FAM126B;+++[B3KUG1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39792 fis, clone SPLEN2003396, weakly similar to Down-regulated by CTNNB1 protein A {ECO:0000313|EMBL:BAG53423.1};+++[C9J115_HUMAN|Unreviewed]SubName: Full=Protein FAM126B {ECO:0000313|Ensembl:ENSP00000412139}; Flags: Fragment;+++[C9JNS4_HUMAN|Unreviewed]SubName: Full=Protein FAM126B {ECO:0000313|Ensembl:ENSP00000408374}; Flags: Fragment;+++[C9JTA1_HUMAN|Unreviewed]SubName: Full=Protein FAM126B {ECO:0000313|Ensembl:ENSP00000401905}; Flags: Fragment;+++[F8W7X4_HUMAN|Unreviewed]SubName: Full=Protein FAM126B {ECO:0000313|Ensembl:ENSP00000286181};"]
[285346,"'ZNF852'",5,8,6.5,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily","[ZN852_HUMAN|Reviewed]RecName: Full=Zinc finger protein 852;"]
[285513,"'GPRIN3'",13.97,42,27.985,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR032745///G protein-regulated inducer of neurite outgrowth, C-terminal+++IPR026646///G protein-regulated inducer of neurite outgrowth","[GRIN3_HUMAN|Reviewed]RecName: Full=G protein-regulated inducer of neurite outgrowth 3; Short=GRIN3;+++[A0AVI5_HUMAN|Unreviewed]SubName: Full=GPRIN family member 3 {ECO:0000313|EMBL:AAI26372.1};"]
[285668,"'C5orf64'",0,2,1,{"$nulls":4},"GO:0005576///extracellular region",{"$nulls":3},"[CE064_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C5orf64; Flags: Precursor;"]
[285955,"'SPDYE1'",2,0,1,"04114///Oocyte meiosis+++04914///Progesterone-mediated oocyte maturation","H01439///Williams-Beuren syndrome",{"$nulls":3},"GO:0019901///protein kinase binding","GO:0045859///regulation of protein kinase activity","IPR020984///Cell cycle regulatory protein Speedy","[SPDE1_HUMAN|Reviewed]RecName: Full=Speedy protein E1; AltName: Full=Williams-Beuren syndrome chromosomal region 19 protein;"]
[286148,"'DPY19L4'",175.04,238.23,206.635,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005637///nuclear inner membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0000030///mannosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0018406///protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan","IPR030040///Probable C-mannosyltransferase DPY19L4+++IPR018732///Dpy-19/Dpy-19-like","[D19L4_HUMAN|Reviewed]RecName: Full=Probable C-mannosyltransferase DPY19L4; EC=2.4.1.-; AltName: Full=Dpy-19-like protein 4; AltName: Full=Protein dpy-19 homolog 4;+++[A0A024R9F2_HUMAN|Unreviewed]SubName: Full=Dpy-19-like 4 (C. elegans), isoform CRA_b {ECO:0000313|EMBL:EAW91724.1};+++[E5RGB7_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L4 {ECO:0000313|Ensembl:ENSP00000428762}; Flags: Fragment;+++[E5RGH1_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L4 {ECO:0000313|Ensembl:ENSP00000430162};+++[H0YAT0_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L4 {ECO:0000313|Ensembl:ENSP00000428041}; Flags: Fragment;+++[H0YBI1_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L4 {ECO:0000313|Ensembl:ENSP00000429559}; Flags: Fragment;+++[H0YBK6_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L4 {ECO:0000313|Ensembl:ENSP00000429711}; Flags: Fragment;+++[H0YBL6_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L4 {ECO:0000313|Ensembl:ENSP00000429785}; Flags: Fragment;+++[H0YBV9_HUMAN|Unreviewed]SubName: Full=Probable C-mannosyltransferase DPY19L4 {ECO:0000313|Ensembl:ENSP00000430417}; Flags: Fragment;"]
[286343,"'LURAP1L'",130,88,109,{"$nulls":6},"GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling","IPR037443///Leucine rich adaptor protein 1+++IPR039499///Leucine rich adaptor protein 1/25","[LUR1L_HUMAN|Reviewed]RecName: Full=Leucine rich adaptor protein 1-like;"]
[2870,"'GRK6'",398,327,362.5,"05032///Morphine addiction+++04341///Hedgehog signaling pathway - fly+++04144///Endocytosis+++04062///Chemokine signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0004674///protein serine/threonine kinase activity+++GO:0047696///beta-adrenergic receptor kinase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0004703///G protein-coupled receptor kinase activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0016055///Wnt signaling pathway","IPR000239///GPCR kinase+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site+++IPR036305///RGS domain superfamily+++IPR000961///AGC-kinase, C-terminal+++IPR016137///RGS domain","[GRK6_HUMAN|Reviewed]RecName: Full=G protein-coupled receptor kinase 6; EC=2.7.11.16; AltName: Full=G protein-coupled receptor kinase GRK6;+++[B3KPS5_HUMAN|Unreviewed]RecName: Full=G protein-coupled receptor kinase {ECO:0000256|RuleBase:RU000308}; EC=2.7.11.- {ECO:0000256|RuleBase:RU000308};+++[D6R9V4_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase 6 {ECO:0000313|Ensembl:ENSP00000422873}; Flags: Fragment;+++[D6RC88_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase 6 {ECO:0000313|Ensembl:ENSP00000422342}; Flags: Fragment;+++[D6RDA3_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase 6 {ECO:0000313|Ensembl:ENSP00000425391}; Flags: Fragment;+++[D6RHC7_HUMAN|Unreviewed]RecName: Full=G protein-coupled receptor kinase {ECO:0000256|RuleBase:RU000308}; EC=2.7.11.- {ECO:0000256|RuleBase:RU000308}; Flags: Fragment;+++[D6RHX8_HUMAN|Unreviewed]RecName: Full=G protein-coupled receptor kinase {ECO:0000256|RuleBase:RU000308}; EC=2.7.11.- {ECO:0000256|RuleBase:RU000308};+++[F8W9W2_HUMAN|Unreviewed]RecName: Full=G protein-coupled receptor kinase {ECO:0000256|RuleBase:RU000308}; EC=2.7.11.- {ECO:0000256|RuleBase:RU000308};+++[H0Y967_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase 6 {ECO:0000313|Ensembl:ENSP00000423174}; Flags: Fragment;+++[Q96AD6_HUMAN|Unreviewed]RecName: Full=G protein-coupled receptor kinase {ECO:0000256|RuleBase:RU000308}; EC=2.7.11.- {ECO:0000256|RuleBase:RU000308};"]
[2890,"'GRIA1'",18,13,15.5,"04723///Retrograde endocannabinoid signaling+++04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse+++04730///Long-term depression+++04720///Long-term potentiation+++04024///cAMP signaling pathway+++05014///Amyotrophic lateral sclerosis (ALS)+++05031///Amphetamine addiction+++05033///Nicotine addiction+++04728///Dopaminergic synapse+++04713///Circadian entrainment",{"$nulls":3},"GO:0009986///cell surface+++GO:0005768///endosome+++GO:0014069///postsynaptic density+++GO:0005783///endoplasmic reticulum+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0097060///synaptic membrane+++GO:0044308///axonal spine+++GO:0032281///AMPA glutamate receptor complex+++GO:0005886///plasma membrane+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016020///membrane+++GO:0098794///postsynapse+++GO:0031901///early endosome membrane+++GO:0098978///glutamatergic synapse+++GO:0032590///dendrite membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0030425///dendrite+++GO:0044309///neuron spine+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection+++GO:0000139///Golgi membrane+++GO:0055037///recycling endosome+++GO:0043025///neuronal cell body+++GO:0042995///cell projection+++GO:0008021///synaptic vesicle+++GO:0045211///postsynaptic membrane+++GO:0036477///somatodendritic compartment+++GO:0030666///endocytic vesicle membrane+++GO:0032591///dendritic spine membrane+++GO:0030054///cell junction+++GO:0098839///postsynaptic density membrane+++GO:0008328///ionotropic glutamate receptor complex+++GO:0055038///recycling endosome membrane","GO:0005515///protein binding+++GO:1904315///transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential+++GO:0099583///neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration+++GO:0008066///glutamate receptor activity+++GO:0004971///AMPA glutamate receptor activity+++GO:0038023///signaling receptor activity+++GO:0001540///amyloid-beta binding+++GO:0004970///ionotropic glutamate receptor activity+++GO:0030165///PDZ domain binding+++GO:0005216///ion channel activity","GO:0099566///regulation of postsynaptic cytosolic calcium ion concentration+++GO:0031623///receptor internalization+++GO:0006811///ion transport+++GO:0007165///signal transduction+++GO:0048208///COPII vesicle coating+++GO:0007616///long-term memory+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0060078///regulation of postsynaptic membrane potential+++GO:0034220///ion transmembrane transport+++GO:0060292///long-term synaptic depression+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007268///chemical synaptic transmission","IPR001320///Ionotropic glutamate receptor+++IPR028082///Periplasmic binding protein-like I+++IPR019594///Ionotropic glutamate receptor, L-glutamate and glycine-binding domain+++IPR001508///Ionotropic glutamate receptor, metazoa+++IPR001828///Receptor, ligand binding region","[GRIA1_HUMAN|Reviewed]RecName: Full=Glutamate receptor 1; Short=GluR-1; AltName: Full=AMPA-selective glutamate receptor 1; AltName: Full=GluR-A; AltName: Full=GluR-K1; AltName: Full=Glutamate receptor ionotropic, AMPA 1; Short=GluA1; Flags: Precursor;+++[C5IJI6_HUMAN|Unreviewed]SubName: Full=Glutamate receptor 1 variant {ECO:0000313|EMBL:ACR45954.1}; Flags: Fragment;+++[Q59GL5_HUMAN|Unreviewed]SubName: Full=Glutamate receptor, ionotropic, AMPA 1 variant {ECO:0000313|EMBL:BAD92331.1}; Flags: Fragment;"]
[28965,"'SLC27A6'",6,7,6.5,"04931///Insulin resistance+++03320///PPAR signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0042383///sarcolemma","GO:0003824///catalytic activity+++GO:0016874///ligase activity+++GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0005324///long-chain fatty acid transporter activity+++GO:0000166///nucleotide binding+++GO:0015245///fatty acid transmembrane transporter activity","GO:0001676///long-chain fatty acid metabolic process+++GO:0000038///very long-chain fatty acid metabolic process+++GO:0006869///lipid transport+++GO:0015909///long-chain fatty acid transport+++GO:0006631///fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0015908///fatty acid transport","IPR030309///Fatty acid transport protein 6+++IPR025110///AMP-binding enzyme, C-terminal domain+++IPR000873///AMP-dependent synthetase/ligase+++IPR020845///AMP-binding, conserved site","[S27A6_HUMAN|Reviewed]RecName: Full=Long-chain fatty acid transport protein 6; Short=FATP-6; Short=Fatty acid transport protein 6; AltName: Full=Fatty-acid-coenzyme A ligase, very long-chain 2; AltName: Full=Solute carrier family 27 member 6; AltName: Full=Very long-chain acyl-CoA synthetase homolog 1; Short=VLCSH1; Short=hVLCS-H1;+++[B2R8P6_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ94000, highly similar to Homo sapiens solute carrier family 27 (fatty acid transporter),member 6 (SLC27A6), mRNA {ECO:0000313|EMBL:BAG36243.1};+++[D6RAJ2_HUMAN|Unreviewed]SubName: Full=Long-chain fatty acid transport protein 6 {ECO:0000313|Ensembl:ENSP00000421759}; Flags: Fragment;"]
[28982,"'FLVCR1'",66,56,61,null,"H01036///Posterior column ataxia with retinitis pigmentosa (PCARP)+++H01120///Proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (PVHH)",null,null,"GO:0005739///mitochondrion+++GO:0031966///mitochondrial membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0015232///heme transporter activity+++GO:0005515///protein binding+++GO:0020037///heme binding+++GO:0005215///transporter activity","GO:0001568///blood vessel development+++GO:0007275///multicellular organism development+++GO:0043249///erythrocyte maturation+++GO:0001701///in utero embryonic development+++GO:0046620///regulation of organ growth+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0097037///heme export+++GO:0006839///mitochondrial transport+++GO:0015886///heme transport+++GO:0048536///spleen development+++GO:0055085///transmembrane transport+++GO:0035108///limb morphogenesis+++GO:0006879///cellular iron ion homeostasis+++GO:0035264///multicellular organism growth+++GO:0030218///erythrocyte differentiation+++GO:0060323///head morphogenesis+++GO:0042733///embryonic digit morphogenesis","IPR020846///Major facilitator superfamily domain+++IPR036259///MFS transporter superfamily+++IPR011701///Major facilitator superfamily","[FLVC1_HUMAN|Reviewed]RecName: Full=Feline leukemia virus subgroup C receptor-related protein 1; Short=Feline leukemia virus subgroup C receptor; Short=hFLVCR;+++[B2RB38_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95288, highly similar to Homo sapiens feline leukemia virus subgroup C cellular receptor (FLVCR), mRNA {ECO:0000313|EMBL:BAG37085.1};+++[H7C3Z2_HUMAN|Unreviewed]SubName: Full=Feline leukemia virus subgroup C receptor-related protein 1 {ECO:0000313|Ensembl:ENSP00000414680}; Flags: Fragment;"]
[2900,"'GRIK4'",22,15,18.5,"04080///Neuroactive ligand-receptor interaction+++04724///Glutamatergic synapse",{"$nulls":3},"GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0016020///membrane+++GO:0045211///postsynaptic membrane+++GO:0099055///integral component of postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0099056///integral component of presynaptic membrane+++GO:0032983///kainate selective glutamate receptor complex+++GO:0042734///presynaptic membrane","GO:0004970///ionotropic glutamate receptor activity+++GO:0015277///kainate selective glutamate receptor activity+++GO:0008066///glutamate receptor activity+++GO:0038023///signaling receptor activity+++GO:0005216///ion channel activity","GO:0006811///ion transport+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007215///glutamate receptor signaling pathway+++GO:0035249///synaptic transmission, glutamatergic+++GO:0035235///ionotropic glutamate receptor signaling pathway+++GO:0034220///ion transmembrane transport+++GO:0007268///chemical synaptic transmission","IPR001320///Ionotropic glutamate receptor+++IPR001508///Ionotropic glutamate receptor, metazoa+++IPR001828///Receptor, ligand binding region+++IPR019594///Ionotropic glutamate receptor, L-glutamate and glycine-binding domain+++IPR028082///Periplasmic binding protein-like I","[GRIK4_HUMAN|Reviewed]RecName: Full=Glutamate receptor ionotropic, kainate 4; Short=GluK4; AltName: Full=Excitatory amino acid receptor 1; Short=EAA1; AltName: Full=Glutamate receptor KA-1; Short=KA1; Flags: Precursor;+++[A6H8K8_HUMAN|Unreviewed]SubName: Full=GRIK4 protein {ECO:0000313|EMBL:AAI46653.1};+++[B2RAP6_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95040, highly similar to Homo sapiens glutamate receptor, ionotropic, kainate 4 (GRIK4), mRNA {ECO:0000313|EMBL:BAG36943.1};"]
[29070,"'CCDC113'",82,104,93,"04064///NF-kappa B signaling pathway+++03008///Ribosome biogenesis in eukaryotes+++04712///Circadian rhythm - plant+++05169///Epstein-Barr virus infection+++04140///Autophagy - animal+++04520///Adherens junction+++04137///Mitophagy - animal+++05162///Measles+++05168///Herpes simplex infection+++04139///Mitophagy - yeast+++04310///Wnt signaling pathway",{"$nulls":3},"GO:0034451///centriolar satellite+++GO:0005815///microtubule organizing center+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0005515///protein binding","GO:0060271///cilium assembly+++GO:0030030///cell projection organization","IPR025254///Domain of unknown function DUF4201","[CC113_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 113;+++[A0A087WWI8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 113 {ECO:0000313|Ensembl:ENSP00000480255};+++[H3BMZ8_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 113 {ECO:0000313|Ensembl:ENSP00000454618};+++[H3BQS9_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 113 {ECO:0000313|Ensembl:ENSP00000455923}; Flags: Fragment;"]
[29089,"'UBE2T'",62,51,56.5,"03460///Fanconi anemia pathway","H00238///Fanconi anemia",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0004842///ubiquitin-protein transferase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0003682///chromatin binding+++GO:0061631///ubiquitin conjugating enzyme activity","GO:0006281///DNA repair+++GO:0070936///protein K48-linked ubiquitination+++GO:0070534///protein K63-linked ubiquitination+++GO:0070979///protein K11-linked ubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016567///protein ubiquitination+++GO:0044314///protein K27-linked ubiquitination+++GO:0006513///protein monoubiquitination+++GO:0035519///protein K29-linked ubiquitination+++GO:0085020///protein K6-linked ubiquitination+++GO:0036297///interstrand cross-link repair+++GO:0051865///protein autoubiquitination","IPR023313///Ubiquitin-conjugating enzyme, active site+++IPR016135///Ubiquitin-conjugating enzyme/RWD-like+++IPR000608///Ubiquitin-conjugating enzyme E2","[UBE2T_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 T; EC=2.3.2.23 {ECO:0000269|PubMed:20061386}; AltName: Full=Cell proliferation-inducing gene 50 protein; AltName: Full=E2 ubiquitin-conjugating enzyme T; AltName: Full=Ubiquitin carrier protein T; AltName: Full=Ubiquitin-protein ligase T;+++[A0A024R9A9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2T (Putative), isoform CRA_a {ECO:0000313|EMBL:EAW91415.1};+++[A0A2R8Y812_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 T {ECO:0000313|Ensembl:ENSP00000496572};"]
[29105,"'CFAP20'",670,571,620.5,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0036064///ciliary basal body+++GO:0005814///centriole+++GO:0005874///microtubule+++GO:0005929///cilium","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0060296///regulation of cilium beat frequency involved in ciliary motility+++GO:2000147///positive regulation of cell motility+++GO:0018095///protein polyglutamylation+++GO:0007275///multicellular organism development+++GO:0060271///cilium assembly+++GO:2000253///positive regulation of feeding behavior","IPR007714///Cilia/flagella-associated protein 20/WDR90/C3orf67","[CFA20_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 20; AltName: Full=Basal body up-regulated protein 22; AltName: Full=Transcription factor IIB;+++[H3BPA3_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 20 {ECO:0000313|Ensembl:ENSP00000455220}; Flags: Fragment;"]
[29121,"'CLEC2D'",14.55,28.02,21.285,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0009986///cell surface","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity","GO:0050776///regulation of immune response+++GO:0007166///cell surface receptor signaling pathway","IPR004301///Nucleoplasmin family+++IPR033992///Natural killer cell receptor-like, C-type lectin-like domain+++IPR036824///Nucleoplasmin core domain superfamily+++IPR016186///C-type lectin-like/link domain superfamily+++IPR032569///Nucleophosmin, C-terminal+++IPR001304///C-type lectin-like+++IPR024057///Nucleoplasmin core domain+++IPR038101///Nucleophosmin, C-terminal domain superfamily+++IPR016187///C-type lectin fold","[CLC2D_HUMAN|Reviewed]RecName: Full=C-type lectin domain family 2 member D; AltName: Full=Lectin-like NK cell receptor; AltName: Full=Lectin-like transcript 1; Short=LLT-1; AltName: Full=Osteoclast inhibitory lectin;+++[A0A024RAP1_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2, member D, isoform CRA_b {ECO:0000313|EMBL:EAW96116.1};+++[A0A0C4DG81_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D {ECO:0000313|Ensembl:ENSP00000413045}; Flags: Fragment;+++[A0A0C4DGG4_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D {ECO:0000313|Ensembl:ENSP00000437861}; Flags: Fragment;+++[F5H0P0_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D {ECO:0000313|Ensembl:ENSP00000438735};+++[F5H5U4_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D {ECO:0000313|Ensembl:ENSP00000443110};+++[F8WF99_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D {ECO:0000313|Ensembl:ENSP00000399744};+++[H0YGG6_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D {ECO:0000313|Ensembl:ENSP00000443177}; Flags: Fragment;+++[H0YH49_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D {ECO:0000313|Ensembl:ENSP00000446028}; Flags: Fragment;+++[V9HVU7_HUMAN|Unreviewed]SubName: Full=Alternative protein CLEC2D {ECO:0000313|EMBL:CCO13710.1};+++[W8JD10_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D variant 2 {ECO:0000313|EMBL:AHK61106.1};+++[W8JE22_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D variant 1 {ECO:0000313|EMBL:AHK61105.1};+++[W8JNK3_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D variant 4 {ECO:0000313|EMBL:AHK61108.1};+++[W8JXM2_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D variant 3 {ECO:0000313|EMBL:AHK61107.1};+++[W8S9T2_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D isoform 10 {ECO:0000313|EMBL:AHM10387.1}; SubName: Full=C-type lectin domain family 2 member D isoform 7 {ECO:0000313|EMBL:AHM10384.1};+++[W8SBA0_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D isoform 11 {ECO:0000313|EMBL:AHM10388.1};+++[W8SJH0_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D isoform 9 {ECO:0000313|EMBL:AHM10386.1};+++[W8SND9_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D isoform 8 {ECO:0000313|EMBL:AHM10385.1};+++[W8T7N2_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 2 member D isoform 12 {ECO:0000313|EMBL:AHM10389.1};"]
[2923,"'PDIA3'",9307,10155,9731,"05163///Human cytomegalovirus infection+++04612///Antigen processing and presentation+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0055038///recycling endosome membrane+++GO:0043209///myelin sheath+++GO:0005615///extracellular space+++GO:0042470///melanosome+++GO:0005925///focal adhesion+++GO:0005623///cell+++GO:0005783///endoplasmic reticulum+++GO:0042824///MHC class I peptide loading complex+++GO:0005788///endoplasmic reticulum lumen+++GO:0045335///phagocytic vesicle+++GO:0070062///extracellular exosome","GO:0003756///protein disulfide isomerase activity+++GO:0003723///RNA binding+++GO:0015036///disulfide oxidoreductase activity+++GO:0016853///isomerase activity+++GO:0005515///protein binding+++GO:0015037///peptide disulfide oxidoreductase activity+++GO:0042802///identical protein binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004629///phospholipase C activity","GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0045454///cell redox homeostasis+++GO:0055114///oxidation-reduction process+++GO:0006508///proteolysis+++GO:0098761///cellular response to interleukin-7+++GO:0034976///response to endoplasmic reticulum stress+++GO:0034975///protein folding in endoplasmic reticulum+++GO:0006457///protein folding+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway","IPR005792///Protein disulphide isomerase+++IPR017937///Thioredoxin, conserved site+++IPR005788///Disulphide isomerase+++IPR013766///Thioredoxin domain+++IPR036249///Thioredoxin-like superfamily","[PDIA3_HUMAN|Reviewed]RecName: Full=Protein disulfide-isomerase A3; EC=5.3.4.1; AltName: Full=58 kDa glucose-regulated protein; AltName: Full=58 kDa microsomal protein; Short=p58; AltName: Full=Disulfide isomerase ER-60; AltName: Full=Endoplasmic reticulum resident protein 57; Short=ER protein 57; Short=ERp57; AltName: Full=Endoplasmic reticulum resident protein 60; Short=ER protein 60; Short=ERp60; Flags: Precursor;+++[F8WBS6_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A3 {ECO:0000313|Ensembl:ENSP00000398005};+++[F8WBW5_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A3 {ECO:0000313|Ensembl:ENSP00000391111};+++[H7BZJ3_HUMAN|Unreviewed]SubName: Full=Protein disulfide-isomerase A3 {ECO:0000313|Ensembl:ENSP00000389906}; Flags: Fragment;+++[L8EAE7_HUMAN|Unreviewed]SubName: Full=Alternative protein PDIA3 {ECO:0000313|EMBL:CCQ43313.1};+++[V9HVY3_HUMAN|Unreviewed]RecName: Full=Protein disulfide-isomerase {ECO:0000256|RuleBase:RU361130}; EC=5.3.4.1 {ECO:0000256|RuleBase:RU361130};"]
[2953,"'GSTT2'",1.2,0,0.6,"05204///Chemical carcinogenesis+++01524///Platinum drug resistance+++00980///Metabolism of xenobiotics by cytochrome P450+++05225///Hepatocellular carcinoma+++05200///Pathways in cancer+++00480///Glutathione metabolism+++00982///Drug metabolism - cytochrome P450+++00983///Drug metabolism - other enzymes+++05418///Fluid shear stress and atherosclerosis","H00516///Cleft lip and/or cleft palate+++H00024///Prostate cancer",null,"R07094///2-(S-glutathionyl)acetyl-chloride:glutathione 2-(S-glutathionyl)acetyltransferase   2-(S-Glutathionyl)acetyl chloride + Glutathione <=> 2-(S-Glutathionyl)acetyl glutathione + Hydrochloric acid+++R07092///1,1-dichloroethylene-epoxide:glutathione S-(chloroepoxyethyl)transferase [2-(S-glutathionyl)acetyl-chloride-forming]   1,1-Dichloroethylene epoxide + Glutathione <=> 2-(S-Glutathionyl)acetyl chloride + Hydrochloric acid+++R07093///chloroacetyl-chloride:glutathione S-chloroacetyltransferase   Chloroacetyl chloride + Glutathione <=> S-(2-Chloroacetyl)glutathione + Hydrochloric acid+++R07113///1,2-dibromoethane:glutathione ethylenetransferase (episulfonium-forming)   1,2-Dibromoethane + Glutathione + H+ <=> Glutathione episulfonium ion + 2 Hydrobromic acid+++R07024///1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene+++R08280///4-glutathionyl cyclophosphamide hydrolase   Aldophosphamide + Glutathione <=> 4-Glutathionyl cyclophosphamide + H2O+++R07023///1-nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-7,8-oxide + Glutathione <=> 1-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene+++R07004///(1S)-hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthalene+++R11905///Hepatotoxins + Glutathione <=> R-S-Glutathione+++R03522///RX:glutathione R-transferase   RX + Glutathione <=> Halide + R-S-Glutathione+++R07003///(1R)-glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1S,2R)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthalene+++R07025///1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene+++R07002///(1R)-hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene glutathione-lyase (epoxide-forming)   (1R,2S)-Naphthalene 1,2-oxide + Glutathione <=> (1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthalene+++R07116///2-bromoacetaldehyde:glutathione S-(formylmethyl)transferase   2-Bromoacetaldehyde + Glutathione <=> S-(Formylmethyl)glutathione + Hydrobromic acid+++R07026///1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene glutathione-lyase (epoxide-forming)   1-Nitronaphthalene-5,6-oxide + Glutathione <=> 1-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene+++R07069///3,4-dihydro-3-hydroxy-4-S-glutathionyl bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-3,4-oxide + Glutathione <=> 3,4-Dihydro-3-hydroxy-4-S-glutathionyl bromobenzene+++R07083///4,5-dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene glutathione-lyase (epoxide-forming)   Benzo[a]pyrene-4,5-oxide + Glutathione <=> 4,5-Dihydro-4-hydroxy-5-S-glutathionyl-benzo[a]pyrene+++R07070///2,3-dihydro-2-S-glutathionyl-3-hydroxy bromobenzene glutathione-lyase (epoxide-forming)   Bromobenzene-2,3-oxide + Glutathione <=> 2,3-Dihydro-2-S-glutathionyl-3-hydroxy bromobenzene+++R07091///S-(2,2-dichloro-1-hydroxy)ethyl-glutathione 2,2-dichloroacetaldehyde-lyase (glutathione-forming)   2,2-Dichloroacetaldehyde + Glutathione <=> S-(2,2-Dichloro-1-hydroxy)ethyl glutathione+++R07100///trichloroethene:glutathione S-(1,2-dichlorovinyl)transferase   Trichloroethene + Glutathione <=> S-(1,2-Dichlorovinyl)glutathione + Hydrochloric acid+++R07084///7,8-dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene hydrolase   Benzo[a]pyrene-7,8-diol + Glutathione <=> 7,8-Dihydro-7-hydroxy-8-S-glutathionyl-benzo[a]pyrene + H2O+++R09409///glutathione-S-transferase   Aflatoxin B1-exo-8,9-epoxide + Glutathione <=> Aflatoxin B1exo-8,9-epoxide-GSH","GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0004364///glutathione transferase activity","GO:0006749///glutathione metabolic process","IPR004046///Glutathione S-transferase, C-terminal+++IPR004045///Glutathione S-transferase, N-terminal+++IPR040075///Glutathione S-transferase Theta, N-terminal+++IPR040079///Glutathione Transferase family+++IPR036249///Thioredoxin-like superfamily+++IPR010987///Glutathione S-transferase, C-terminal-like+++IPR040077///Glutathione S-transferase Theta, C-terminal+++IPR036282///Glutathione S-transferase, C-terminal domain superfamily","[GST2_HUMAN|Reviewed]RecName: Full=Glutathione S-transferase theta-2; EC=2.5.1.18; AltName: Full=GST class-theta-2;+++[A0A087WY67_HUMAN|Unreviewed]SubName: Full=Glutathione S-transferase theta-2 {ECO:0000313|Ensembl:ENSP00000481555};+++[G9J6Q4_HUMAN|Unreviewed]SubName: Full=GSTT2 {ECO:0000313|EMBL:AEW26630.1};+++[G9J6Q6_HUMAN|Unreviewed]SubName: Full=GSTT2 {ECO:0000313|EMBL:AEW26632.1};+++[Q6IB75_HUMAN|Unreviewed]SubName: Full=GSTT2 protein {ECO:0000313|EMBL:CAG33210.1};"]
[2971,"'GTF3A'",923,699,811,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0008097///5S rRNA binding","GO:0042273///ribosomal large subunit biogenesis+++GO:0042254///ribosome biogenesis+++GO:0006383///transcription by RNA polymerase III+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0009303///rRNA transcription","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[TF3A_HUMAN|Reviewed]RecName: Full=Transcription factor IIIA; Short=TFIIIA;+++[A0A024RDQ5_HUMAN|Unreviewed]SubName: Full=General transcription factor IIIA, isoform CRA_a {ECO:0000313|EMBL:EAX08404.1}; Flags: Fragment;+++[A0A1X7SBT5_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIA {ECO:0000313|Ensembl:ENSP00000370532};+++[H7BZ51_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIA {ECO:0000313|Ensembl:ENSP00000387806};+++[H7BZH7_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIA {ECO:0000313|Ensembl:ENSP00000389655};+++[H7C326_HUMAN|Unreviewed]SubName: Full=Transcription factor IIIA {ECO:0000313|Ensembl:ENSP00000409175};"]
[29785,"'CYP2S1'",19,21,20,"01100///Metabolic pathways+++00980///Metabolism of xenobiotics by cytochrome P450+++00830///Retinol metabolism",null,null,"R08391///Retinoate + NADPH + H+ + Oxygen <=> all-trans-5,6-Epoxyretinoic acid + NADP+ + H2O+++R07001///Naphthalene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)   Naphthalene + NADPH + Oxygen + H+ <=> (1S,2R)-Naphthalene 1,2-oxide + NADP+ + H2O+++R08392///Retinoate + NADPH + H+ + Oxygen <=> all-trans-4-Hydroxyretinoic acid + NADP+ + H2O+++R07000///naphthalene, NADPH:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)   Naphthalene + NADPH + Oxygen + H+ <=> (1R,2S)-Naphthalene 1,2-oxide + NADP+ + H2O","GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm+++GO:0031090///organelle membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0070330///aromatase activity+++GO:0008395///steroid hydroxylase activity+++GO:0020037///heme binding+++GO:0008392///arachidonic acid epoxygenase activity+++GO:0005506///iron ion binding+++GO:0046872///metal ion binding+++GO:0016705///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen+++GO:0004497///monooxygenase activity+++GO:0016712///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen+++GO:0008401///retinoic acid 4-hydroxylase activity","GO:0019373///epoxygenase P450 pathway+++GO:0042738///exogenous drug catabolic process+++GO:0055114///oxidation-reduction process+++GO:0006805///xenobiotic metabolic process+++GO:0006082///organic acid metabolic process","IPR002401///Cytochrome P450, E-class, group I+++IPR008067///Cytochrome P450, E-class, group I, CYP2A-like+++IPR036396///Cytochrome P450 superfamily+++IPR001128///Cytochrome P450+++IPR017972///Cytochrome P450, conserved site","[CP2S1_HUMAN|Reviewed]RecName: Full=Cytochrome P450 2S1; EC=1.14.14.1; AltName: Full=CYPIIS1;+++[M0QY51_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 2S1 {ECO:0000313|Ensembl:ENSP00000469593};+++[M0QYI2_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 2S1 {ECO:0000313|Ensembl:ENSP00000469850}; Flags: Fragment;+++[M0R057_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 2S1 {ECO:0000313|Ensembl:ENSP00000471016}; Flags: Fragment;+++[M0R152_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 2S1 {ECO:0000313|Ensembl:ENSP00000471637}; Flags: Fragment;+++[M0R2G8_HUMAN|Unreviewed]SubName: Full=Cytochrome P450 2S1 {ECO:0000313|Ensembl:ENSP00000472555};"]
[29855,"'UBN1'",794,1055,924.5,{"$nulls":4},"GO:0030054///cell junction+++GO:0016605///PML body+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005654///nucleoplasm+++GO:0005923///bicellular tight junction","GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006325///chromatin organization+++GO:0006336///DNA replication-independent nucleosome assembly+++GO:0016032///viral process","IPR026936///Ubinuclein-1+++IPR014840///Hpc2-related domain+++IPR026947///Ubinuclein middle domain","[UBN1_HUMAN|Reviewed]RecName: Full=Ubinuclein-1; AltName: Full=HIRA-binding protein; AltName: Full=Protein VT4; AltName: Full=Ubiquitously expressed nuclear protein;+++[K7EJT1_HUMAN|Unreviewed]SubName: Full=Ubinuclein-1 {ECO:0000313|Ensembl:ENSP00000465309}; Flags: Fragment;+++[K7EQR1_HUMAN|Unreviewed]SubName: Full=Ubinuclein-1 {ECO:0000313|Ensembl:ENSP00000467942}; Flags: Fragment;+++[K7ER78_HUMAN|Unreviewed]SubName: Full=Ubinuclein-1 {ECO:0000313|Ensembl:ENSP00000468143}; Flags: Fragment;+++[K7ESM4_HUMAN|Unreviewed]SubName: Full=Ubinuclein-1 {ECO:0000313|Ensembl:ENSP00000468776}; Flags: Fragment;"]
[29880,"'ALG5'",240,226,233,"01100///Metabolic pathways+++00510///N-Glycan biosynthesis",null,"M00055///N-glycan precursor biosynthesis","R01005///UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase   UDP-glucose + Dolichyl phosphate <=> UDP + Dolichyl beta-D-glucosyl phosphate","GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity+++GO:0004576///oligosaccharyl transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0004581///dolichyl-phosphate beta-glucosyltransferase activity","GO:0006487///protein N-linked glycosylation+++GO:0006486///protein glycosylation+++GO:0007368///determination of left/right symmetry+++GO:0018279///protein N-linked glycosylation via asparagine","IPR035518///Dolichyl-phosphate beta-glucosyltransferase+++IPR001173///Glycosyltransferase 2-like+++IPR029044///Nucleotide-diphospho-sugar transferases","[ALG5_HUMAN|Reviewed]RecName: Full=Dolichyl-phosphate beta-glucosyltransferase; Short=DolP-glucosyltransferase; EC=2.4.1.117; AltName: Full=Asparagine-linked glycosylation protein 5 homolog;"]
[2990,"'GUSB'",475,399,437,"00860///Porphyrin and chlorophyll metabolism+++04142///Lysosome+++01110///Biosynthesis of secondary metabolites+++00040///Pentose and glucuronate interconversions+++01100///Metabolic pathways+++00944///Flavone and flavonol biosynthesis+++00531///Glycosaminoglycan degradation+++00983///Drug metabolism - other enzymes","H00132///Mucopolysaccharidosis type VII (MPS7)+++H00421///Mucopolysaccharidosis (MPS)","M00077///Chondroitin sulfate degradation+++M00076///Dermatan sulfate degradation+++M00129///Ascorbate biosynthesis, animals, glucose-1P => ascorbate+++M00014///Glucuronate pathway (uronate pathway)+++M00078///Heparan sulfate degradation","R08127///beta-D-glucuronoside glucuronosohydrolase   Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide + H2O <=> Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide] + D-Glucuronate+++R01478///beta-D-glucuronoside glucuronosohydrolase   H2O + beta-D-Glucuronoside <=> D-Glucuronate + Alcohol+++R10830///beta-D-glucuronoside glucuronosohydrolase   G00526 + H2O <=> G00711 + D-Glucuronate+++R08260///SN38 glucuronide glucuronosohydrolase   SN38 glucuronide + H2O <=> SN-38 + D-Glucuronate+++R07818///G13040 + H2O <=> G09660 + D-Glucuronate+++R04979///Bilirubin beta-diglucuronide glucuronosohydrolase   Bilirubin beta-diglucuronide + 2 H2O + 3 Reduced acceptor <=> D-Urobilinogen + 2 D-Glucuronate + 3 Acceptor","GO:0035578///azurophil granule lumen+++GO:0043202///lysosomal lumen+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005764///lysosome","GO:0030246///carbohydrate binding+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0016787///hydrolase activity+++GO:0004566///beta-glucuronidase activity+++GO:0019904///protein domain specific binding+++GO:0005102///signaling receptor binding","GO:0030214///hyaluronan catabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006027///glycosaminoglycan catabolic process+++GO:0019391///glucuronoside catabolic process+++GO:0008152///metabolic process+++GO:0043312///neutrophil degranulation","IPR008979///Galactose-binding-like domain superfamily+++IPR006103///Glycoside hydrolase family 2, catalytic domain+++IPR006104///Glycosyl hydrolases family 2, sugar binding domain+++IPR006102///Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich+++IPR017853///Glycoside hydrolase superfamily+++IPR023230///Glycoside hydrolase, family 2, conserved site+++IPR013783///Immunoglobulin-like fold+++IPR036156///Beta-Galactosidase/glucuronidase domain superfamily+++IPR023232///Glycoside hydrolase, family 2, active site+++IPR006101///Glycoside hydrolase, family 2","[BGLR_HUMAN|Reviewed]RecName: Full=Beta-glucuronidase; EC=3.2.1.31; AltName: Full=Beta-G1; Flags: Precursor;+++[F2Z3L6_HUMAN|Unreviewed]SubName: Full=Beta-glucuronidase {ECO:0000313|Ensembl:ENSP00000411262};+++[F8WBK6_HUMAN|Unreviewed]SubName: Full=Beta-glucuronidase {ECO:0000313|Ensembl:ENSP00000411859};"]
[29923,"'HILPDA'",103.35,102,102.675,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005811///lipid droplet+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0030141///secretory granule+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space","GO:0005102///signaling receptor binding+++GO:0005515///protein binding","GO:0071456///cellular response to hypoxia+++GO:0010884///positive regulation of lipid storage+++GO:0001819///positive regulation of cytokine production+++GO:0008284///positive regulation of cell proliferation+++GO:0034389///lipid droplet organization+++GO:0035425///autocrine signaling","IPR026190///Hypoxia-inducible lipid droplet-associated protein","[HLPDA_HUMAN|Reviewed]RecName: Full=Hypoxia-inducible lipid droplet-associated protein; AltName: Full=Hypoxia-inducible gene 2 protein;"]
[29944,"'PNMA3'",30,42,36,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0043065///positive regulation of apoptotic process","IPR001878///Zinc finger, CCHC-type+++IPR036875///Zinc finger, CCHC-type superfamily+++IPR026523///Paraneoplastic antigen Ma","[PNMA3_HUMAN|Reviewed]RecName: Full=Paraneoplastic antigen Ma3;"]
[29964,"'PRICKLE4'",67,89,78,"04310///Wnt signaling pathway","H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,null,"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0046872///metal ion binding+++GO:0003674///molecular_function+++GO:0008270///zinc ion binding","GO:0008150///biological_process+++GO:0015031///protein transport","IPR001781///Zinc finger, LIM-type+++IPR010442///PET domain","[PRIC4_HUMAN|Reviewed]RecName: Full=Prickle-like protein 4; AltName: Full=Overexpressed breast tumor protein;+++[A0A024RCZ7_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 49, isoform CRA_c {ECO:0000313|EMBL:EAX04064.1};+++[A0A0U1RQR5_HUMAN|Unreviewed]SubName: Full=Prickle-like protein 4 {ECO:0000313|Ensembl:ENSP00000489132}; Flags: Fragment;"]
[29988,"'SLC2A8'",252,235,243.5,{"$nulls":4},"GO:0030665///clathrin-coated vesicle membrane+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005887///integral component of plasma membrane+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0008021///synaptic vesicle","GO:0022857///transmembrane transporter activity+++GO:0005536///glucose binding+++GO:0005351///carbohydrate:proton symporter activity+++GO:0005355///glucose transmembrane transporter activity+++GO:0055056///D-glucose transmembrane transporter activity+++GO:0005215///transporter activity","GO:1904659///glucose transmembrane transport+++GO:0007141///male meiosis I+++GO:0005975///carbohydrate metabolic process+++GO:0061024///membrane organization+++GO:1902600///proton transmembrane transport+++GO:0001666///response to hypoxia+++GO:0055085///transmembrane transport+++GO:0008645///hexose transmembrane transport+++GO:0008643///carbohydrate transport+++GO:0008286///insulin receptor signaling pathway","IPR036259///MFS transporter superfamily+++IPR003663///Sugar/inositol transporter+++IPR005828///Major facilitator,  sugar transporter-like+++IPR005829///Sugar transporter, conserved site+++IPR020846///Major facilitator superfamily domain","[GTR8_HUMAN|Reviewed]RecName: Full=Solute carrier family 2, facilitated glucose transporter member 8; AltName: Full=Glucose transporter type 8; Short=GLUT-8; AltName: Full=Glucose transporter type X1;+++[A0A024R871_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_a {ECO:0000313|EMBL:EAW87662.1};+++[A0A087WT42_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_c {ECO:0000313|EMBL:EAW87663.1}; SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000477568};+++[H0Y7M6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000413973}; Flags: Fragment;+++[Q5VVV3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000392434}; Flags: Fragment;+++[Q5VVV4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000391213}; Flags: Fragment;+++[Q5VVV5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000389070}; Flags: Fragment;+++[Q5VVV6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000404893}; Flags: Fragment;+++[Q5VVV9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_b {ECO:0000313|EMBL:EAW87661.1}; SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000362458};+++[Q5VVW0_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000411726}; Flags: Fragment;+++[Q5VVW5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, facilitated glucose transporter member 8 {ECO:0000313|Ensembl:ENSP00000362450};+++[Q8WZ05_HUMAN|Unreviewed]SubName: Full=Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_d {ECO:0000313|EMBL:EAW87664.1};"]
[3005,"'H1F0'",1328,1203,1265.5,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0016604///nuclear body+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin+++GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus+++GO:0000786///nucleosome+++GO:0015629///actin cytoskeleton+++GO:0005719///nuclear euchromatin","GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0031490///chromatin DNA binding+++GO:0003680///AT DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0031492///nucleosomal DNA binding","GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0006342///chromatin silencing+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030261///chromosome condensation+++GO:0045910///negative regulation of DNA recombination+++GO:0016584///nucleosome positioning+++GO:0006334///nucleosome assembly+++GO:0031936///negative regulation of chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006309///apoptotic DNA fragmentation","IPR005819///Histone H5+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR005818///Linker histone H1/H5, domain H15+++IPR036388///Winged helix-like DNA-binding domain superfamily","[H10_HUMAN|Reviewed]RecName: Full=Histone H1.0; AltName: Full=Histone H1'; AltName: Full=Histone H1(0); Contains: RecName: Full=Histone H1.0, N-terminally processed;"]
[3029,"'HAGH'",880,530,705,"00620///Pyruvate metabolism",null,null,"R01736///(R)-S-Lactoylglutathione hydrolase   (R)-S-Lactoylglutathione + H2O <=> Glutathione + (R)-Lactate","GO:0005829///cytosol+++GO:0005759///mitochondrial matrix+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0004416///hydroxyacylglutathione hydrolase activity+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding","GO:0006090///pyruvate metabolic process+++GO:0006750///glutathione biosynthetic process+++GO:0019243///methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione","IPR001279///Metallo-beta-lactamase+++IPR017782///Hydroxyacylglutathione hydrolase+++IPR036866///Ribonuclease Z/Hydroxyacylglutathione hydrolase-like+++IPR032282///Hydroxyacylglutathione hydrolase, C-terminal domain+++IPR035680///Hydroxyacylglutathione hydrolase, MBL domain","[GLO2_HUMAN|Reviewed]RecName: Full=Hydroxyacylglutathione hydrolase, mitochondrial {ECO:0000303|PubMed:15117945}; EC=3.1.2.6; AltName: Full=Glyoxalase II; Short=Glx II; Flags: Precursor;+++[H3BPK3_HUMAN|Unreviewed]SubName: Full=Hydroxyacylglutathione hydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000455355}; Flags: Fragment;+++[H3BPQ4_HUMAN|Unreviewed]SubName: Full=Hydroxyacylglutathione hydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000455422};+++[H3BQW8_HUMAN|Unreviewed]SubName: Full=Hydroxyacylglutathione hydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000455970}; Flags: Fragment;+++[H3BV79_HUMAN|Unreviewed]SubName: Full=Hydroxyacylglutathione hydrolase, mitochondrial {ECO:0000313|Ensembl:ENSP00000457986}; Flags: Fragment;"]
[3059,"'HCLS1'",0,2,1,"05205///Proteoglycans in cancer+++05100///Bacterial invasion of epithelial cells+++05130///Pathogenic Escherichia coli infection+++04530///Tight junction+++05131///Shigellosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005667///transcription factor complex+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0019901///protein kinase binding+++GO:0017124///SH3 domain binding+++GO:0044877///protein-containing complex binding+++GO:0001085///RNA polymerase II transcription factor binding","GO:0030218///erythrocyte differentiation+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0030854///positive regulation of granulocyte differentiation+++GO:0035556///intracellular signal transduction+++GO:0008284///positive regulation of cell proliferation+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0071345///cellular response to cytokine stimulus+++GO:2000107///negative regulation of leukocyte apoptotic process+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0009725///response to hormone+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0030833///regulation of actin filament polymerization+++GO:0045651///positive regulation of macrophage differentiation+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0042307///positive regulation of protein import into nucleus+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030041///actin filament polymerization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR036028///SH3-like domain superfamily+++IPR028534///Hematopoietic lineage cell-specific protein+++IPR001452///SH3 domain+++IPR003134///Hs1/Cortactin","[HCLS1_HUMAN|Reviewed]RecName: Full=Hematopoietic lineage cell-specific protein; AltName: Full=Hematopoietic cell-specific LYN substrate 1; AltName: Full=LckBP1; AltName: Full=p75;+++[E7EVW7_HUMAN|Unreviewed]SubName: Full=Hematopoietic lineage cell-specific protein {ECO:0000313|Ensembl:ENSP00000387645};+++[F8WDD5_HUMAN|Unreviewed]SubName: Full=Hematopoietic lineage cell-specific protein {ECO:0000313|Ensembl:ENSP00000420507};+++[F8WEZ6_HUMAN|Unreviewed]SubName: Full=Hematopoietic lineage cell-specific protein {ECO:0000313|Ensembl:ENSP00000419614};"]
[3081,"'HGD'",0,1,0.5,"00643///Styrene degradation+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++00350///Tyrosine metabolism","H00163///Alkaptonuria","M00044///Tyrosine degradation, tyrosine => homogentisate","R02519///Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)   Homogentisate + Oxygen <=> 4-Maleylacetoacetate","GO:0005829///cytosol+++GO:0070062///extracellular exosome","GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0004411///homogentisate 1,2-dioxygenase activity+++GO:0051213///dioxygenase activity+++GO:0016491///oxidoreductase activity","GO:0006572///tyrosine catabolic process+++GO:0006570///tyrosine metabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0006559///L-phenylalanine catabolic process+++GO:0055114///oxidation-reduction process","IPR005708///Homogentisate 1,2-dioxygenase+++IPR014710///RmlC-like jelly roll fold+++IPR011051///RmlC-like cupin domain superfamily","[HGD_HUMAN|Reviewed]RecName: Full=Homogentisate 1,2-dioxygenase; EC=1.13.11.5; AltName: Full=Homogentisate oxygenase; AltName: Full=Homogentisic acid oxidase; AltName: Full=Homogentisicase;+++[B3KW64_HUMAN|Unreviewed]SubName: Full=cDNA FLJ42297 fis, clone TLIVE2009087, highly similar to HOMOGENTISATE 1,2-DIOXYGENASE {ECO:0000313|EMBL:BAG54026.1};+++[C9JTX9_HUMAN|Unreviewed]SubName: Full=Homogentisate 1,2-dioxygenase {ECO:0000313|Ensembl:ENSP00000419560}; Flags: Fragment;+++[H7C4R8_HUMAN|Unreviewed]SubName: Full=Homogentisate 1,2-dioxygenase {ECO:0000313|Ensembl:ENSP00000417977}; Flags: Fragment;+++[H7C576_HUMAN|Unreviewed]SubName: Full=Homogentisate 1,2-dioxygenase {ECO:0000313|Ensembl:ENSP00000419163}; Flags: Fragment;+++[H7C5G7_HUMAN|Unreviewed]SubName: Full=Homogentisate 1,2-dioxygenase {ECO:0000313|Ensembl:ENSP00000419838}; Flags: Fragment;+++[Q8WW71_HUMAN|Unreviewed]SubName: Full=Homogentisate 1,2-dioxygenase (Homogentisate oxidase) {ECO:0000313|EMBL:AAH20792.1};"]
[30836,"'DNTTIP2'",451,492,471.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR014810///Fcf2 pre-rRNA processing, C-terminal+++IPR039883///Fcf2/DNTTIP2","[TDIF2_HUMAN|Reviewed]RecName: Full=Deoxynucleotidyltransferase terminal-interacting protein 2; AltName: Full=Estrogen receptor-binding protein; AltName: Full=LPTS-interacting protein 2; Short=LPTS-RP2; AltName: Full=Terminal deoxynucleotidyltransferase-interacting factor 2; Short=TdIF2; Short=TdT-interacting factor 2;+++[E9PRB3_HUMAN|Unreviewed]SubName: Full=Deoxynucleotidyltransferase terminal-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000434261}; Flags: Fragment;+++[J3KP30_HUMAN|Unreviewed]SubName: Full=Deoxynucleotidyltransferase terminal-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000352137};"]
[3094,"'HINT1'",1467,1354,1410.5,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0005634///nucleus","GO:0016787///hydrolase activity+++GO:0005080///protein kinase C binding+++GO:0000166///nucleotide binding+++GO:0003824///catalytic activity","GO:0006915///apoptotic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0009154///purine ribonucleotide catabolic process+++GO:0007165///signal transduction+++GO:0050850///positive regulation of calcium-mediated signaling","IPR001310///Histidine triad (HIT) protein+++IPR036265///HIT-like superfamily+++IPR011146///HIT-like domain+++IPR019808///Histidine triad, conserved site","[HINT1_HUMAN|Reviewed]RecName: Full=Histidine triad nucleotide-binding protein 1; EC=3.-.-.-; AltName: Full=Adenosine 5'-monophosphoramidase; AltName: Full=Protein kinase C inhibitor 1; AltName: Full=Protein kinase C-interacting protein 1; Short=PKCI-1;+++[D6RC06_HUMAN|Unreviewed]SubName: Full=Histidine triad nucleotide-binding protein 1 {ECO:0000313|Ensembl:ENSP00000422444};+++[D6RD60_HUMAN|Unreviewed]SubName: Full=Histidine triad nucleotide-binding protein 1 {ECO:0000313|Ensembl:ENSP00000427008};+++[D6RE99_HUMAN|Unreviewed]SubName: Full=Histidine triad nucleotide-binding protein 1 {ECO:0000313|Ensembl:ENSP00000426860};+++[D6REP8_HUMAN|Unreviewed]SubName: Full=Histidine triad nucleotide-binding protein 1 {ECO:0000313|Ensembl:ENSP00000424974};+++[H0YC49_HUMAN|Unreviewed]SubName: Full=Histidine triad nucleotide-binding protein 1 {ECO:0000313|Ensembl:ENSP00000430909}; Flags: Fragment;"]
[3112,"'HLA-DOB'",7,4,5.5,"05416///Viral myocarditis+++05145///Toxoplasmosis+++05332///Graft-versus-host disease+++05310///Asthma+++05320///Autoimmune thyroid disease+++05330///Allograft rejection+++05152///Tuberculosis+++04658///Th1 and Th2 cell differentiation+++05323///Rheumatoid arthritis+++04145///Phagosome+++05168///Herpes simplex infection+++04940///Type I diabetes mellitus+++05321///Inflammatory bowel disease (IBD)+++05322///Systemic lupus erythematosus+++04659///Th17 cell differentiation+++04612///Antigen processing and presentation+++05164///Influenza A+++05166///HTLV-I infection+++04514///Cell adhesion molecules (CAMs)+++05150///Staphylococcus aureus infection+++04672///Intestinal immune network for IgA production+++05140///Leishmaniasis+++04640///Hematopoietic cell lineage","H00295///Viral myocarditis+++H00408///Type I diabetes mellitus+++H00342///Tuberculosis+++H01362///Dermatitis herpetiformis+++H01490///Multiple sclerosis+++H01502///Sjogren's syndrome+++H01516///Adult onset Still's disease+++H01492///Systemic sclerosis+++H00080///Systemic lupus erythematosus+++H02123///Celiac disease+++H00083///Allograft rejection+++H00082///Graves' disease+++H00081///Hashimoto's thyroiditis+++H01504///Vogt-Koyanagi-Harada syndrome+++H00294///Dilated cardiomyopathy (DCM)+++H01468///Eosinophilic granulomatosis with polyangiitis+++H00079///Asthma+++H01698///Giant cell arteritis",null,null,"GO:0016020///membrane+++GO:0005768///endosome+++GO:0005765///lysosomal membrane+++GO:0010008///endosome membrane+++GO:0016021///integral component of membrane+++GO:0042613///MHC class II protein complex+++GO:0005764///lysosome","GO:0023026///MHC class II protein complex binding+++GO:0032395///MHC class II receptor activity","GO:0006955///immune response+++GO:0002587///negative regulation of antigen processing and presentation of peptide antigen via MHC class II+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0019882///antigen processing and presentation+++GO:0002504///antigen processing and presentation of peptide or polysaccharide antigen via MHC class II+++GO:0002376///immune system process","IPR011162///MHC classes I/II-like antigen recognition protein+++IPR007110///Immunoglobulin-like domain+++IPR000353///MHC class II, beta chain, N-terminal+++IPR003006///Immunoglobulin/major histocompatibility complex, conserved site+++IPR003597///Immunoglobulin C1-set+++IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily+++IPR014745///MHC class II, alpha/beta chain, N-terminal","[DOB_HUMAN|Reviewed]RecName: Full=HLA class II histocompatibility antigen, DO beta chain; AltName: Full=MHC class II antigen DOB; Flags: Precursor;+++[A0A140T935_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000390574}; Flags: Fragment;+++[A0A140T945_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000391708}; Flags: Fragment;+++[A0A140T9F2_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000401290}; Flags: Fragment;+++[A0A140T9L2_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000406128}; Flags: Fragment;+++[A0A140T9U5_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000413915}; Flags: Fragment;+++[A0A140T9Z3_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000431178}; Flags: Fragment;+++[A0A140TA22_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000437213}; Flags: Fragment;+++[A0A1V0E3R2_HUMAN|Unreviewed]SubName: Full=HLA-DOB {ECO:0000313|EMBL:ARB08424.1};+++[A0A1V0E3U2_HUMAN|Unreviewed]SubName: Full=HLA-DOB {ECO:0000313|EMBL:ARB08427.1};+++[B7Z742_HUMAN|Unreviewed]SubName: Full=Major histocompatibility complex, class II, DO beta, isoform CRA_b {ECO:0000313|EMBL:EAX03639.1}; SubName: Full=cDNA FLJ55403, highly similar to HLA class II histocompatibility antigen, DObeta chain {ECO:0000313|EMBL:BAH13478.1}; SubName: Full=cDNA, FLJ79096, highly similar to HLA class II histocompatibility antigen, DObeta chain {ECO:0000313|EMBL:BAH14568.1};+++[E9PI00_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000436618};+++[H0Y4X4_HUMAN|Unreviewed]SubName: Full=HLA class II histocompatibility antigen, DO beta chain {ECO:0000313|Ensembl:ENSP00000394860}; Flags: Fragment;+++[Q5QNS2_HUMAN|Unreviewed]SubName: Full=HLA-DOB {ECO:0000313|EMBL:ARB08421.1}; SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AAV97948.1}; SubName: Full=Major histocompatibility complex, class II, DO beta, isoform CRA_a {ECO:0000313|EMBL:EAX03638.1};+++[Q6FHE3_HUMAN|Unreviewed]SubName: Full=HLA-DOB protein {ECO:0000313|EMBL:CAG46610.1};+++[X5CF66_HUMAN|Unreviewed]SubName: Full=HLA-DOB {ECO:0000313|EMBL:ARB08420.1}; SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AHW47957.1};+++[X5D174_HUMAN|Unreviewed]SubName: Full=HLA-DOB {ECO:0000313|EMBL:ARB08422.1}; SubName: Full=MHC class II antigen {ECO:0000313|EMBL:AHW47974.1};"]
[3146,"'HMGB1'",1711.51,1401.51,1556.51,"03410///Base excision repair+++04217///Necroptosis+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0035868///alphav-beta3 integrin-HMGB1 complex+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:0009986///cell surface+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000793///condensed chromosome+++GO:0005769///early endosome+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000790///nuclear chromatin+++GO:0016020///membrane+++GO:0043005///neuron projection+++GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus+++GO:0005768///endosome","GO:0003697///single-stranded DNA binding+++GO:0019958///C-X-C chemokine binding+++GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0000405///bubble DNA binding+++GO:0030295///protein kinase activator activity+++GO:0050786///RAGE receptor binding+++GO:0008301///DNA binding, bending+++GO:0003684///damaged DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0001530///lipopolysaccharide binding+++GO:0003690///double-stranded DNA binding+++GO:0003713///transcription coactivator activity+++GO:0003723///RNA binding+++GO:0097100///supercoiled DNA binding+++GO:0070182///DNA polymerase binding+++GO:0016829///lyase activity+++GO:0070491///repressing transcription factor binding+++GO:0042056///chemoattractant activity+++GO:0005178///integrin binding+++GO:0001786///phosphatidylserine binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0000400///four-way junction DNA binding+++GO:0003727///single-stranded RNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0010858///calcium-dependent protein kinase regulator activity","GO:0032502///developmental process+++GO:0060326///cell chemotaxis+++GO:0030324///lung development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010469///regulation of signaling receptor activity+++GO:2000778///positive regulation of interleukin-6 secretion+++GO:1902741///positive regulation of interferon-alpha secretion+++GO:0002218///activation of innate immune response+++GO:0051103///DNA ligation involved in DNA repair+++GO:0050718///positive regulation of interleukin-1 beta secretion+++GO:0043065///positive regulation of apoptotic process+++GO:0035711///T-helper 1 cell activation+++GO:0034145///positive regulation of toll-like receptor 4 signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0001935///endothelial cell proliferation+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0032760///positive regulation of tumor necrosis factor production+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0046330///positive regulation of JNK cascade+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0006338///chromatin remodeling+++GO:0017055///negative regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:0035767///endothelial cell chemotaxis+++GO:0033151///V(D)J recombination+++GO:0006342///chromatin silencing+++GO:0006309///apoptotic DNA fragmentation+++GO:0032735///positive regulation of interleukin-12 production+++GO:0006310///DNA recombination+++GO:0002840///regulation of T cell mediated immune response to tumor cell+++GO:0002224///toll-like receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0043312///neutrophil degranulation+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0098761///cellular response to interleukin-7+++GO:0002270///plasmacytoid dendritic cell activation+++GO:0050918///positive chemotaxis+++GO:0010508///positive regulation of autophagy+++GO:0002281///macrophage activation involved in immune response+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:0002250///adaptive immune response+++GO:0006935///chemotaxis+++GO:0032727///positive regulation of interferon-alpha production+++GO:0043277///apoptotic cell clearance+++GO:0032755///positive regulation of interleukin-6 production+++GO:0001934///positive regulation of protein phosphorylation+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0032425///positive regulation of mismatch repair+++GO:0097350///neutrophil clearance+++GO:0043537///negative regulation of blood vessel endothelial cell migration+++GO:0045063///T-helper 1 cell differentiation+++GO:0006281///DNA repair+++GO:0045859///regulation of protein kinase activity+++GO:0001773///myeloid dendritic cell activation+++GO:2001200///positive regulation of dendritic cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0002437///inflammatory response to antigenic stimulus+++GO:0042104///positive regulation of activated T cell proliferation+++GO:0031497///chromatin assembly+++GO:0010506///regulation of autophagy+++GO:0043410///positive regulation of MAPK cascade+++GO:0032392///DNA geometric change+++GO:0031175///neuron projection development+++GO:0002407///dendritic cell chemotaxis+++GO:2000819///regulation of nucleotide-excision repair+++GO:0006265///DNA topological change+++GO:0032072///regulation of restriction endodeoxyribonuclease activity+++GO:0001654///eye development+++GO:0045819///positive regulation of glycogen catabolic process+++GO:0043388///positive regulation of DNA binding+++GO:0006284///base-excision repair+++GO:0050716///positive regulation of interleukin-1 secretion+++GO:0032689///negative regulation of interferon-gamma production+++GO:0043371///negative regulation of CD4-positive, alpha-beta T cell differentiation+++GO:0090026///positive regulation of monocyte chemotaxis+++GO:1905564///positive regulation of vascular endothelial cell proliferation+++GO:0045639///positive regulation of myeloid cell differentiation+++GO:0032733///positive regulation of interleukin-10 production+++GO:0051384///response to glucocorticoid+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0051106///positive regulation of DNA ligation+++GO:0006914///autophagy+++GO:0002643///regulation of tolerance induction+++GO:1990774///tumor necrosis factor secretion+++GO:0034165///positive regulation of toll-like receptor 9 signaling pathway+++GO:2000426///negative regulation of apoptotic cell clearance+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0045089///positive regulation of innate immune response+++GO:0002376///immune system process+++GO:0071639///positive regulation of monocyte chemotactic protein-1 production+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090303///positive regulation of wound healing+++GO:0032147///activation of protein kinase activity","IPR016024///Armadillo-type fold+++IPR017967///HMG box A DNA-binding domain, conserved site+++IPR036910///High mobility group box domain superfamily+++IPR009071///High mobility group box domain","[HMGB1_HUMAN|Reviewed]RecName: Full=High mobility group protein B1; AltName: Full=High mobility group protein 1; Short=HMG-1;+++[A0A024RDR0_HUMAN|Unreviewed]SubName: Full=High-mobility group box 1, isoform CRA_a {ECO:0000313|EMBL:EAX08459.1};+++[A0A286R9D9_HUMAN|Unreviewed]SubName: Full=High mobility group box 1 {ECO:0000313|EMBL:ASV72502.1}; Flags: Fragment;+++[A0A286R9F1_HUMAN|Unreviewed]SubName: Full=High mobility group box 1 {ECO:0000313|EMBL:ASV72501.1}; Flags: Fragment;+++[Q5T7C4_HUMAN|Unreviewed]SubName: Full=High mobility group protein B1 {ECO:0000313|Ensembl:ENSP00000369904};+++[Q9NYD7_HUMAN|Unreviewed]SubName: Full=High mobility group 1 protein {ECO:0000313|EMBL:AAK64599.1}; SubName: Full=High mobility group protein HMG1 {ECO:0000313|EMBL:AAF71287.1}; Flags: Fragment;"]
[317,"'APAF1'",112,191,151.5,"05200///Pathways in cancer+++05134///Legionellosis+++05014///Amyotrophic lateral sclerosis (ALS)+++05010///Alzheimer's disease+++04115///p53 signaling pathway+++05222///Small cell lung cancer+++05012///Parkinson's disease+++04210///Apoptosis+++01524///Platinum drug resistance+++05016///Huntington's disease+++05152///Tuberculosis+++05161///Hepatitis B+++04215///Apoptosis - multiple species+++04214///Apoptosis - fly",null,"M00685///Apoptotic machinery",null,"GO:0005576///extracellular region+++GO:0043293///apoptosome+++GO:0034774///secretory granule lumen+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005737///cytoplasm","GO:0043531///ADP binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0000166///nucleotide binding+++GO:0031072///heat shock protein binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding","GO:0007584///response to nutrient+++GO:0030154///cell differentiation+++GO:0001666///response to hypoxia+++GO:0043312///neutrophil degranulation+++GO:0007568///aging+++GO:0006915///apoptotic process+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0030900///forebrain development+++GO:0001822///kidney development+++GO:0051260///protein homooligomerization+++GO:0007420///brain development+++GO:1902510///regulation of apoptotic DNA fragmentation+++GO:0010659///cardiac muscle cell apoptotic process+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0042981///regulation of apoptotic process+++GO:0007275///multicellular organism development+++GO:0097190///apoptotic signaling pathway+++GO:0008635///activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c+++GO:0007399///nervous system development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0001843///neural tube closure+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0072432///response to G1 DNA damage checkpoint signaling+++GO:0097193///intrinsic apoptotic signaling pathway+++GO:0051402///neuron apoptotic process+++GO:0043065///positive regulation of apoptotic process","IPR017251///Apoptotic protease-activating factor 1+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001315///CARD domain+++IPR001680///WD40 repeat+++IPR019775///WD40 repeat, conserved site+++IPR036322///WD40-repeat-containing domain superfamily+++IPR017986///WD40-repeat-containing domain+++IPR011029///Death-like domain superfamily+++IPR020472///G-protein beta WD-40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR002182///NB-ARC+++IPR037963///Apoptotic Protease-Activating Factor 1, CARD domain","[APAF_HUMAN|Reviewed]RecName: Full=Apoptotic protease-activating factor 1 {ECO:0000305}; Short=APAF-1;+++[A5YM44_HUMAN|Unreviewed]RecName: Full=Apoptotic protease-activating factor 1 {ECO:0000256|PIRNR:PIRNR037646}; Short=APAF-1 {ECO:0000256|PIRNR:PIRNR037646};+++[A7E2A2_HUMAN|Unreviewed]RecName: Full=Apoptotic protease-activating factor 1 {ECO:0000256|PIRNR:PIRNR037646}; Short=APAF-1 {ECO:0000256|PIRNR:PIRNR037646};+++[C9JLV4_HUMAN|Unreviewed]SubName: Full=Apoptotic protease-activating factor 1 {ECO:0000313|Ensembl:ENSP00000448161};+++[F8VNZ0_HUMAN|Unreviewed]SubName: Full=Apoptotic protease-activating factor 1 {ECO:0000313|Ensembl:ENSP00000450175};+++[L8E801_HUMAN|Unreviewed]SubName: Full=Alternative protein APAF1 {ECO:0000313|EMBL:CCQ43415.1};"]
[3178,"'HNRNPA1'",2604.78,2292.77,2448.775,"03040///Spliceosome","H02031///Inclusion body myopathy with Paget disease of bone and frontotemporal dementia+++H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005737///cytoplasm+++GO:0005681///spliceosomal complex+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0016020///membrane","GO:0098505///G-rich strand telomeric DNA binding+++GO:0042802///identical protein binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0036002///pre-mRNA binding+++GO:0061752///telomeric repeat-containing RNA binding+++GO:0035198///miRNA binding+++GO:0003729///mRNA binding+++GO:0003727///single-stranded RNA binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0003697///single-stranded DNA binding","GO:0016070///RNA metabolic process+++GO:0000398///mRNA splicing, via spliceosome+++GO:1903936///cellular response to sodium arsenite+++GO:0051028///mRNA transport+++GO:0051170///import into nucleus+++GO:0016032///viral process+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0042149///cellular response to glucose starvation+++GO:0006405///RNA export from nucleus+++GO:0051168///nuclear export","IPR021662///Nuclear factor hnRNPA1+++IPR034845///hnRNP A1, RNA recognition motif 1+++IPR034803///hnRNP A1, RNA recognition motif 2+++IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR035979///RNA-binding domain superfamily","[ROA1_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein A1; Short=hnRNP A1; AltName: Full=Helix-destabilizing protein; AltName: Full=Single-strand RNA-binding protein; AltName: Full=hnRNP core protein A1; Contains: RecName: Full=Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed;+++[A0A024RAZ7_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1, isoform CRA_b {ECO:0000313|EMBL:EAW96768.1};+++[A0A024RB53_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1, isoform CRA_a {ECO:0000313|EMBL:EAW96769.1};+++[F8VTQ5_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|Ensembl:ENSP00000448117}; Flags: Fragment;+++[F8VYN5_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|Ensembl:ENSP00000448917}; Flags: Fragment;+++[F8VZ49_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|Ensembl:ENSP00000447782}; Flags: Fragment;+++[F8W646_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|Ensembl:ENSP00000448229}; Flags: Fragment;+++[F8W6I7_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|Ensembl:ENSP00000333504};+++[H0YH80_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|Ensembl:ENSP00000446486}; Flags: Fragment;+++[Q0VAC0_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|EMBL:AAI21134.1};+++[Q3MI39_HUMAN|Unreviewed]SubName: Full=HNRPA1 protein {ECO:0000313|EMBL:AAI04238.1}; Flags: Fragment;+++[Q6IPF2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein A1 {ECO:0000313|EMBL:AAH71945.1};"]
[320,"'APBA1'",199,266,232.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0048471///perinuclear region of cytoplasm+++GO:0043197///dendritic spine+++GO:0048787///presynaptic active zone membrane+++GO:0005634///nucleus+++GO:0008021///synaptic vesicle+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0016020///membrane","GO:0001540///amyloid-beta binding+++GO:0005515///protein binding","GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0065003///protein-containing complex assembly+++GO:0014047///glutamate secretion+++GO:0007269///neurotransmitter secretion+++GO:0007399///nervous system development+++GO:0015031///protein transport+++GO:0010468///regulation of gene expression+++GO:0007155///cell adhesion+++GO:0006886///intracellular protein transport+++GO:0007268///chemical synaptic transmission+++GO:0008088///axo-dendritic transport+++GO:0007626///locomotory behavior+++GO:0001701///in utero embryonic development+++GO:0035264///multicellular organism growth+++GO:0014051///gamma-aminobutyric acid secretion","IPR030530///Amyloid beta A4 precursor protein-binding family A member 1+++IPR006020///PTB/PI domain+++IPR036034///PDZ superfamily+++IPR001478///PDZ domain+++IPR011993///PH-like domain superfamily","[APBA1_HUMAN|Reviewed]RecName: Full=Amyloid-beta A4 precursor protein-binding family A member 1; AltName: Full=Adapter protein X11alpha; AltName: Full=Neuron-specific X11 protein; AltName: Full=Neuronal Munc18-1-interacting protein 1; Short=Mint-1;+++[A0A0D9SFA9_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family A member 1 {ECO:0000313|Ensembl:ENSP00000486435}; Flags: Fragment;+++[A0A0G2JMD7_HUMAN|Unreviewed]SubName: Full=Amyloid-beta A4 precursor protein-binding family A member 1 {ECO:0000313|Ensembl:ENSP00000479031}; Flags: Fragment;"]
[3226,"'HOXC10'",5,0,2.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005654///nucleoplasm","GO:0043565///sequence-specific DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0009954///proximal/distal pattern formation+++GO:0050905///neuromuscular process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0030326///embryonic limb morphogenesis+++GO:0007275///multicellular organism development+++GO:0009952///anterior/posterior pattern specification+++GO:0021520///spinal cord motor neuron cell fate specification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0001501///skeletal system development","IPR020479///Homeobox domain, metazoa+++IPR001356///Homeobox domain+++IPR009057///Homeobox-like domain superfamily+++IPR017970///Homeobox, conserved site","[HXC10_HUMAN|Reviewed]RecName: Full=Homeobox protein Hox-C10; AltName: Full=Homeobox protein Hox-3I;+++[A0A024RB66_HUMAN|Unreviewed]SubName: Full=Homeobox C10, isoform CRA_b {ECO:0000313|EMBL:EAW96740.1};+++[D6RAG4_HUMAN|Unreviewed]SubName: Full=Homeobox protein Hox-C10 {ECO:0000313|Ensembl:ENSP00000421946}; Flags: Fragment;+++[Q53XI4_HUMAN|Unreviewed]SubName: Full=Homeo box C10 {ECO:0000313|EMBL:AAP88923.1}; SubName: Full=Homeobox C10, isoform CRA_a {ECO:0000313|EMBL:EAW96738.1}; SubName: Full=cDNA, FLJ94360, Homo sapiens homeo box C10 (HOXC10), mRNA {ECO:0000313|EMBL:BAG36498.1};"]
[3263,"'HPX'",4,6,5,{"$nulls":4},"GO:0071682///endocytic vesicle lumen+++GO:0072562///blood microparticle+++GO:0070062///extracellular exosome+++GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0015232///heme transporter activity+++GO:0008237///metallopeptidase activity","GO:0060332///positive regulation of response to interferon-gamma+++GO:0051246///regulation of protein metabolic process+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0015886///heme transport+++GO:0002925///positive regulation of humoral immune response mediated by circulating immunoglobulin+++GO:0016032///viral process+++GO:0020027///hemoglobin metabolic process+++GO:0006879///cellular iron ion homeostasis+++GO:0006508///proteolysis+++GO:0002639///positive regulation of immunoglobulin production+++GO:0042168///heme metabolic process+++GO:0060335///positive regulation of interferon-gamma-mediated signaling pathway+++GO:0006898///receptor-mediated endocytosis","IPR018487///Hemopexin-like repeats+++IPR036375///Hemopexin-like domain superfamily+++IPR018486///Hemopexin, conserved site+++IPR016358///Hemopexin+++IPR000585///Hemopexin-like domain","[HEMO_HUMAN|Reviewed]RecName: Full=Hemopexin; AltName: Full=Beta-1B-glycoprotein; Flags: Precursor;+++[Q9BS19_HUMAN|Unreviewed]SubName: Full=HPX protein {ECO:0000313|EMBL:AAH05395.1}; SubName: Full=Hemopexin {ECO:0000313|Ensembl:ENSP00000479146};"]
[3281,"'HSBP1'",1308,1114,1211,"04212///Longevity regulating pathway - worm",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003714///transcription corepressor activity+++GO:0042802///identical protein binding","GO:0035987///endodermal cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006936///muscle contraction+++GO:1900034///regulation of cellular response to heat+++GO:0070370///cellular heat acclimation","IPR009643///Heat shock factor binding 1","[HSBP1_HUMAN|Reviewed]RecName: Full=Heat shock factor-binding protein 1; AltName: Full=Nasopharyngeal carcinoma-associated antigen 13; Short=NPC-A-13;+++[H3BR28_HUMAN|Unreviewed]SubName: Full=Heat shock factor-binding protein 1 {ECO:0000313|Ensembl:ENSP00000456049};"]
[3305,"'HSPA1L'",22,23,22.5,"05162///Measles+++04010///MAPK signaling pathway+++05169///Epstein-Barr virus infection+++04213///Longevity regulating pathway - multiple species+++05134///Legionellosis+++04144///Endocytosis+++04141///Protein processing in endoplasmic reticulum+++05145///Toxoplasmosis+++05164///Influenza A+++04915///Estrogen signaling pathway+++03040///Spliceosome+++04612///Antigen processing and presentation",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0072562///blood microparticle+++GO:0005654///nucleoplasm+++GO:0008180///COP9 signalosome+++GO:0002199///zona pellucida receptor complex+++GO:0005829///cytosol","GO:0031072///heat shock protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0005515///protein binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0051787///misfolded protein binding+++GO:0051082///unfolded protein binding+++GO:0005524///ATP binding+++GO:0044183///protein binding involved in protein folding+++GO:0042623///ATPase activity, coupled","GO:0006986///response to unfolded protein+++GO:0034605///cellular response to heat+++GO:0034620///cellular response to unfolded protein+++GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0042026///protein refolding+++GO:1900034///regulation of cellular response to heat+++GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0007339///binding of sperm to zona pellucida","IPR018181///Heat shock protein 70, conserved site+++IPR029047///Heat shock protein 70kD, peptide-binding domain superfamily+++IPR029048///Heat shock protein 70kD, C-terminal domain superfamily+++IPR013126///Heat shock protein 70 family","[HS71L_HUMAN|Reviewed]RecName: Full=Heat shock 70 kDa protein 1-like; Short=Heat shock 70 kDa protein 1L; AltName: Full=Heat shock 70 kDa protein 1-Hom; Short=HSP70-Hom;+++[A0A1U9X7W7_HUMAN|Unreviewed]SubName: Full=HSPA1L {ECO:0000313|EMBL:AQY76885.1};+++[Q53FA3_HUMAN|Unreviewed]SubName: Full=HSPA1L {ECO:0000313|EMBL:AQY76887.1}; SubName: Full=Heat shock 70 kDa protein 1-like {ECO:0000313|Ensembl:ENSP00000409151}; SubName: Full=Heat shock 70kDa protein 1-like variant {ECO:0000313|EMBL:BAD97106.1}; Flags: Fragment;"]
[333,"'APLP1'",6668,6183,6425.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005604///basement membrane+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0046914///transition metal ion binding+++GO:0031696///alpha-2C adrenergic receptor binding+++GO:0031694///alpha-2A adrenergic receptor binding+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0031695///alpha-2B adrenergic receptor binding+++GO:0005515///protein binding+++GO:0008201///heparin binding","GO:0007155///cell adhesion+++GO:0007399///nervous system development+++GO:0106072///negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0006897///endocytosis+++GO:0006915///apoptotic process+++GO:0009887///animal organ morphogenesis+++GO:0071874///cellular response to norepinephrine stimulus","IPR036669///Amyloidogenic glycoprotein, copper-binding domain superfamily+++IPR019744///Amyloidogenic glycoprotein, extracellular domain conserved site+++IPR008155///Amyloidogenic glycoprotein+++IPR036176///E2 domain superfamily+++IPR008154///Amyloidogenic glycoprotein, extracellular+++IPR019543///Beta-amyloid precursor protein C-terminal+++IPR011178///Amyloidogenic glycoprotein, copper-binding+++IPR024329///Amyloidogenic glycoprotein, E2 domain+++IPR015849///Amyloidogenic glycoprotein, heparin-binding+++IPR036454///Amyloidogenic glycoprotein, heparin-binding domain superfamily+++IPR019745///Amyloidogenic glycoprotein, intracellular domain, conserved site","[APLP1_HUMAN|Reviewed]RecName: Full=Amyloid-like protein 1; Short=APLP; Short=APLP-1; Contains: RecName: Full=C30; Flags: Precursor;+++[B7Z4G8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56046, highly similar to Amyloid-like protein 1 (APLP)(APLP-1) {ECO:0000313|EMBL:BAH12554.1};+++[F5GZ08_HUMAN|Unreviewed]SubName: Full=Amyloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000441501};+++[K7ELK0_HUMAN|Unreviewed]SubName: Full=Amyloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000466116}; Flags: Fragment;+++[K7EMN4_HUMAN|Unreviewed]SubName: Full=Amyloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000466576}; Flags: Fragment;+++[K7EMS1_HUMAN|Unreviewed]SubName: Full=Amyloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000466623};+++[K7EQJ4_HUMAN|Unreviewed]SubName: Full=Amyloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000467854}; Flags: Fragment;+++[S4R3U6_HUMAN|Unreviewed]SubName: Full=Amyloid-like protein 1 {ECO:0000313|Ensembl:ENSP00000474762}; Flags: Fragment;"]
[3364,"'HUS1'",127,111,119,"04218///Cellular senescence",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0030896///checkpoint clamp complex+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0035861///site of double-strand break+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0006468///protein phosphorylation+++GO:0000723///telomere maintenance+++GO:0009792///embryo development ending in birth or egg hatching+++GO:0007093///mitotic cell cycle checkpoint+++GO:0006974///cellular response to DNA damage stimulus+++GO:0033314///mitotic DNA replication checkpoint+++GO:0000077///DNA damage checkpoint+++GO:0006281///DNA repair+++GO:0009411///response to UV+++GO:0071479///cellular response to ionizing radiation+++GO:0001932///regulation of protein phosphorylation+++GO:0044778///meiotic DNA integrity checkpoint+++GO:0008156///negative regulation of DNA replication+++GO:0000075///cell cycle checkpoint+++GO:0006289///nucleotide-excision repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0031573///intra-S DNA damage checkpoint","IPR007150///Checkpoint protein Hus1/Mec3+++IPR016580///Cell cycle checkpoint, Hus1","[HUS1_HUMAN|Reviewed]RecName: Full=Checkpoint protein HUS1; Short=hHUS1;+++[A4D2F2_HUMAN|Unreviewed]SubName: Full=HUS1 checkpoint homolog (S. pombe) {ECO:0000313|EMBL:EAL23807.1}; SubName: Full=HUS1 checkpoint homolog (S. pombe), isoform CRA_a {ECO:0000313|EMBL:EAW61001.1}; SubName: Full=cDNA FLJ76255, highly similar to Homo sapiens HUS1 checkpoint homolog (S. pombe) (HUS1), mRNA {ECO:0000313|EMBL:BAF83148.1};+++[C9JA95_HUMAN|Unreviewed]SubName: Full=Checkpoint protein HUS1 {ECO:0000313|Ensembl:ENSP00000398806}; Flags: Fragment;+++[C9JCK8_HUMAN|Unreviewed]SubName: Full=Checkpoint protein HUS1 {ECO:0000313|Ensembl:ENSP00000404855}; Flags: Fragment;+++[F8WAW9_HUMAN|Unreviewed]SubName: Full=Checkpoint protein HUS1 {ECO:0000313|Ensembl:ENSP00000405175};+++[H7C272_HUMAN|Unreviewed]SubName: Full=Checkpoint protein HUS1 {ECO:0000313|Ensembl:ENSP00000404348}; Flags: Fragment;"]
[338440,"'ANO9'",0,6,3,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0017128///phospholipid scramblase activity+++GO:0005229///intracellular calcium activated chloride channel activity+++GO:0005515///protein binding","GO:0006821///chloride transport+++GO:0061588///calcium activated phospholipid scrambling+++GO:0034220///ion transmembrane transport+++GO:0061589///calcium activated phosphatidylserine scrambling+++GO:0061590///calcium activated phosphatidylcholine scrambling+++GO:0061591///calcium activated galactosylceramide scrambling+++GO:1902939///negative regulation of intracellular calcium activated chloride channel activity+++GO:0006869///lipid transport","IPR031290///Anoctamin-9+++IPR007632///Anoctamin","[ANO9_HUMAN|Reviewed]RecName: Full=Anoctamin-9; AltName: Full=Transmembrane protein 16J; AltName: Full=Tumor protein p53-inducible protein 5; AltName: Full=p53-induced gene 5 protein;"]
[339175,"'METTL2A'",198.73,190.51,194.62,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0016427///tRNA (cytosine) methyltransferase activity+++GO:0042803///protein homodimerization activity","GO:0030488///tRNA methylation","IPR026113///Methyltransferase-like+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[MET2A_HUMAN|Reviewed]RecName: Full=Methyltransferase-like protein 2A; EC=2.1.1.-;+++[A0A087WW35_HUMAN|Unreviewed]RecName: Full=Methyltransferase-like protein {ECO:0000256|PIRNR:PIRNR037755}; EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};+++[B3KM33_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10129 fis, clone HEMBA1003033, highly similar to Methyltransferase-like protein 2 {ECO:0000313|EMBL:BAG50845.1};"]
[339453,"'TMEM240'",24,22,23,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0097060///synaptic membrane+++GO:0005886///plasma membrane","GO:0005524///ATP binding","GO:0007005///mitochondrion organization+++GO:0043066///negative regulation of apoptotic process+++GO:0001558///regulation of cell growth","IPR027947///TMEM240 family","[TM240_HUMAN|Reviewed]RecName: Full=Transmembrane protein 240;+++[A0A096LNN7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 240 {ECO:0000313|Ensembl:ENSP00000485135};"]
[339778,"'C2orf70'",0,1,0.5,{"$nulls":4},"GO:0005634///nucleus",null,null,"IPR018902///Uncharacterised protein family UPF0573/UPF0605","[CB070_HUMAN|Reviewed]RecName: Full=UPF0573 protein C2orf70;+++[B8ZZ55_HUMAN|Unreviewed]SubName: Full=UPF0573 protein C2orf70 {ECO:0000313|Ensembl:ENSP00000386615};+++[H7C0N2_HUMAN|Unreviewed]SubName: Full=UPF0573 protein C2orf70 {ECO:0000313|Ensembl:ENSP00000395924}; Flags: Fragment;"]
[340152,"'ZC3H12D'",4.44,5.92,5.18,{"$nulls":4},"GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0000932///P-body+++GO:0005737///cytoplasm","GO:0004519///endonuclease activity+++GO:0046872///metal ion binding+++GO:0004518///nuclease activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0030308///negative regulation of cell growth+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle","IPR000571///Zinc finger, CCCH-type+++IPR021869///Ribonuclease Zc3h12a-like, NYN domain","[ZC12D_HUMAN|Reviewed]RecName: Full=Probable ribonuclease ZC3H12D; EC=3.1.-.-; AltName: Full=MCP-induced protein 4 {ECO:0000303|PubMed:18178554}; AltName: Full=Transformed follicular lymphoma; AltName: Full=Zinc finger CCCH domain-containing protein 12D; AltName: Full=p34 {ECO:0000303|PubMed:17210687};+++[B7ZBA4_HUMAN|Unreviewed]SubName: Full=Probable ribonuclease ZC3H12D {ECO:0000313|Ensembl:ENSP00000387062};+++[H0Y4Y6_HUMAN|Unreviewed]SubName: Full=Probable ribonuclease ZC3H12D {ECO:0000313|Ensembl:ENSP00000395209}; Flags: Fragment;"]
[340481,"'ZDHHC21'",160,252,206,{"$nulls":4},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane","GO:0016409///palmitoyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0019706///protein-cysteine S-palmitoyltransferase activity+++GO:0016740///transferase activity","GO:0048733///sebaceous gland development+++GO:0018345///protein palmitoylation+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0006612///protein targeting to membrane+++GO:0018230///peptidyl-L-cysteine S-palmitoylation+++GO:0001942///hair follicle development","IPR001594///Palmitoyltransferase, DHHC domain","[ZDH21_HUMAN|Reviewed]RecName: Full=Palmitoyltransferase ZDHHC21; EC=2.3.1.225; AltName: Full=Zinc finger DHHC domain-containing protein 21; Short=DHHC-21;"]
[341116,"'MS4A10'",1.01,1,1.005,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane",null,null,"IPR030417///Membrane-spanning 4-domains subfamily A+++IPR007237///CD20-like family","[M4A10_HUMAN|Reviewed]RecName: Full=Membrane-spanning 4-domains subfamily A member 10; AltName: Full=CD20 antigen-like 7;"]
[342132,"'ZNF774'",24,17,20.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN774_HUMAN|Reviewed]RecName: Full=Zinc finger protein 774;+++[E7EQ77_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 774 {ECO:0000313|Ensembl:ENSP00000368383};+++[H0YLG8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 774 {ECO:0000313|Ensembl:ENSP00000453202};+++[H0YNW6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 774 {ECO:0000313|Ensembl:ENSP00000454184}; Flags: Fragment;"]
[3429,"'IFI27'",1103,512,807.5,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005637///nuclear inner membrane+++GO:0016021///integral component of membrane+++GO:0005741///mitochondrial outer membrane+++GO:0005635///nuclear envelope+++GO:0005783///endoplasmic reticulum+++GO:0031966///mitochondrial membrane","GO:0005515///protein binding+++GO:0005521///lamin binding+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0003674///molecular_function+++GO:0042802///identical protein binding","GO:0070936///protein K48-linked ubiquitination+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006915///apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0044827///modulation by host of viral genome replication+++GO:0097191///extrinsic apoptotic signaling pathway+++GO:0097190///apoptotic signaling pathway+++GO:0016032///viral process+++GO:0051607///defense response to virus+++GO:0002376///immune system process+++GO:0046825///regulation of protein export from nucleus+++GO:0060337///type I interferon signaling pathway+++GO:0045087///innate immune response","IPR038213///IFI6/IFI27-like domain superfamily+++IPR009311///Interferon alpha-inducible protein IFI6/IFI27-like","[IFI27_HUMAN|Reviewed]RecName: Full=Interferon alpha-inducible protein 27, mitochondrial {ECO:0000305}; Short=p27; AltName: Full=Interferon alpha-induced 11.5 kDa protein; AltName: Full=Interferon-stimulated gene 12a protein {ECO:0000303|PubMed:14728724}; Short=ISG12(a) {ECO:0000303|PubMed:14728724}; Short=ISG12A {ECO:0000303|PubMed:27673746}; Flags: Precursor;+++[A0A087WUJ8_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27, mitochondrial {ECO:0000313|Ensembl:ENSP00000478718}; Flags: Fragment;+++[A0A087WV79_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27, mitochondrial {ECO:0000313|Ensembl:ENSP00000479250}; Flags: Fragment;+++[A0A087WZR1_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27, mitochondrial {ECO:0000313|Ensembl:ENSP00000482832};+++[A0A087X035_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27, mitochondrial {ECO:0000313|Ensembl:ENSP00000483072}; Flags: Fragment;+++[A0A087X174_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27, mitochondrial {ECO:0000313|Ensembl:ENSP00000483954};+++[G3V4U3_HUMAN|Unreviewed]SubName: Full=Interferon alpha-inducible protein 27, mitochondrial {ECO:0000313|Ensembl:ENSP00000451987}; Flags: Fragment;"]
[343263,"'MYBPHL'",4,5,4.5,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","IPR007110///Immunoglobulin-like domain+++IPR013098///Immunoglobulin I-set+++IPR003961///Fibronectin type III+++IPR036116///Fibronectin type III superfamily+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR003598///Immunoglobulin subtype 2+++IPR003599///Immunoglobulin subtype","[MBPHL_HUMAN|Reviewed]RecName: Full=Myosin-binding protein H-like;"]
[344558,"'SH3RF3'",130,150,140,{"$nulls":5},"GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity","GO:0046330///positive regulation of JNK cascade+++GO:0051865///protein autoubiquitination+++GO:0016567///protein ubiquitination","IPR001841///Zinc finger, RING-type+++IPR036028///SH3-like domain superfamily+++IPR001452///SH3 domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR035816///SH3RF1/SH3RF3, fourth SH3 domain+++IPR017907///Zinc finger, RING-type, conserved site+++IPR035612///SH3RF3, SH3 domain 3","[SH3R3_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase SH3RF3; EC=2.3.2.27 {ECO:0000269|PubMed:20696164}; AltName: Full=Plenty of SH3s 2; AltName: Full=SH3 domain-containing RING finger protein 3; AltName: Full=SH3 multiple domains protein 4;"]
[3456,"'IFNB1'",4,1,2.5,"05164///Influenza A+++04151///PI3K-Akt signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04060///Cytokine-cytokine receptor interaction+++05165///Human papillomavirus infection+++04650///Natural killer cell mediated cytotoxicity+++04380///Osteoclast differentiation+++04621///NOD-like receptor signaling pathway+++04630///Jak-STAT signaling pathway+++04620///Toll-like receptor signaling pathway+++05161///Hepatitis B+++04623///Cytosolic DNA-sensing pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05142///Chagas disease (American trypanosomiasis)+++05152///Tuberculosis+++05163///Human cytomegalovirus infection+++04668///TNF signaling pathway+++04217///Necroptosis+++05160///Hepatitis C+++05162///Measles+++05168///Herpes simplex infection",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0008811///chloramphenicol O-acetyltransferase activity+++GO:0005125///cytokine activity+++GO:0005126///cytokine receptor binding+++GO:0005132///type I interferon receptor binding","GO:0045071///negative regulation of viral genome replication+++GO:0006952///defense response+++GO:0007596///blood coagulation+++GO:0009615///response to virus+++GO:0035458///cellular response to interferon-beta+++GO:0010469///regulation of signaling receptor activity+++GO:0007166///cell surface receptor signaling pathway+++GO:0030101///natural killer cell activation+++GO:0060337///type I interferon signaling pathway+++GO:0045343///regulation of MHC class I biosynthetic process+++GO:0002323///natural killer cell activation involved in immune response+++GO:0030183///B cell differentiation+++GO:0002312///B cell activation involved in immune response+++GO:0071360///cellular response to exogenous dsRNA+++GO:0002286///T cell activation involved in immune response+++GO:0043330///response to exogenous dsRNA+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0002250///adaptive immune response+++GO:0051607///defense response to virus+++GO:0045089///positive regulation of innate immune response+++GO:0033141///positive regulation of peptidyl-serine phosphorylation of STAT protein+++GO:0045581///negative regulation of T cell differentiation+++GO:2000552///negative regulation of T-helper 2 cell cytokine production+++GO:0042100///B cell proliferation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006959///humoral immune response","IPR009079///Four-helical cytokine-like, core+++IPR000471///Interferon alpha/beta/delta+++IPR015588///Interferon beta","[IFNB_HUMAN|Reviewed]RecName: Full=Interferon beta; Short=IFN-beta; AltName: Full=Fibroblast interferon; Flags: Precursor;+++[B5BUQ5_HUMAN|Unreviewed]SubName: Full=Interferon beta {ECO:0000313|EMBL:BAG70305.1}; Flags: Fragment;"]
[346689,"'KLRG2'",2,6,4,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0030246///carbohydrate binding",null,"IPR001304///C-type lectin-like+++IPR033992///Natural killer cell receptor-like, C-type lectin-like domain+++IPR016187///C-type lectin fold+++IPR016186///C-type lectin-like/link domain superfamily","[KLRG2_HUMAN|Reviewed]RecName: Full=Killer cell lectin-like receptor subfamily G member 2; AltName: Full=C-type lectin domain family 15 member B;"]
[347730,"'LRRTM1'",7,8,7.5,{"$nulls":4},"GO:0030424///axon+++GO:0005886///plasma membrane+++GO:0031012///extracellular matrix+++GO:0099055///integral component of postsynaptic membrane+++GO:0060076///excitatory synapse+++GO:0045202///synapse+++GO:0030426///growth cone+++GO:0016021///integral component of membrane+++GO:0005615///extracellular space+++GO:0098982///GABA-ergic synapse+++GO:0099060///integral component of postsynaptic specialization membrane+++GO:0045211///postsynaptic membrane+++GO:0030054///cell junction+++GO:0009986///cell surface+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse","GO:0003674///molecular_function","GO:0002091///negative regulation of receptor internalization+++GO:0050808///synapse organization+++GO:1905606///regulation of presynapse assembly+++GO:0008150///biological_process+++GO:0099151///regulation of postsynaptic density assembly+++GO:0007626///locomotory behavior+++GO:0035418///protein localization to synapse+++GO:0035640///exploration behavior+++GO:0060291///long-term synaptic potentiation+++GO:0051965///positive regulation of synapse assembly","IPR032675///Leucine-rich repeat domain superfamily+++IPR001611///Leucine-rich repeat+++IPR003591///Leucine-rich repeat, typical subtype","[LRRT1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat transmembrane neuronal protein 1; Flags: Precursor;+++[C9JEE2_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat transmembrane neuronal protein 1 {ECO:0000313|Ensembl:ENSP00000415368}; Flags: Fragment;+++[C9JF97_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat transmembrane neuronal protein 1 {ECO:0000313|Ensembl:ENSP00000404557}; Flags: Fragment;+++[C9JPM9_HUMAN|Unreviewed]SubName: Full=Leucine-rich repeat transmembrane neuronal protein 1 {ECO:0000313|Ensembl:ENSP00000389473}; Flags: Fragment;"]
[348094,"'ANKDD1A'",4,7,5.5,{"$nulls":4},"GO:0005576///extracellular region+++GO:1904813///ficolin-1-rich granule lumen",null,"GO:0007165///signal transduction","IPR011029///Death-like domain superfamily+++IPR000488///Death domain+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR039194///Ankyrin repeat and death domain-containing protein 1A/1B+++IPR002110///Ankyrin repeat","[AKD1A_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and death domain-containing protein 1A;+++[A0A0C4DFZ5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and death domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000379073};+++[A0A0C4DGA8_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and death domain containing 1A, isoform CRA_b {ECO:0000313|EMBL:EAW77703.1}; SubName: Full=Ankyrin repeat and death domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000420999};+++[A0A0C4DGZ7_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and death domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000484388};+++[A4QMR4_HUMAN|Unreviewed]SubName: Full=ANKDD1A protein {ECO:0000313|EMBL:AAI01277.1}; Flags: Fragment;+++[D6RD28_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat and death domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000427091};+++[Q6PI29_HUMAN|Unreviewed]SubName: Full=ANKDD1A protein {ECO:0000313|EMBL:AAH47607.1}; Flags: Fragment;+++[Q8TAJ8_HUMAN|Unreviewed]SubName: Full=ANKDD1A protein {ECO:0000313|EMBL:AAH27350.1}; SubName: Full=Ankyrin repeat and death domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000423548}; Flags: Fragment;"]
[348751,"'FTCDNL1'",14,9,11.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane","GO:0016740///transferase activity+++GO:0005542///folic acid binding","GO:0008152///metabolic process","IPR012886///Formiminotransferase, N-terminal subdomain+++IPR022384///Formiminotransferase catalytic domain superfamily+++IPR037064///Formiminotransferase, N-terminal subdomain superfamily","[FONG_HUMAN|Reviewed]RecName: Full=Formiminotransferase N-terminal subdomain-containing protein; AltName: Full=Formiminotransferase-cyclodeaminase N-terminal-like protein; Flags: Precursor;+++[H3BMM2_HUMAN|Unreviewed]SubName: Full=Formiminotransferase N-terminal subdomain-containing protein {ECO:0000313|Ensembl:ENSP00000454447}; SubName: Full=HCG1653746, isoform CRA_c {ECO:0000313|EMBL:EAW70187.1};+++[H3BRX2_HUMAN|Unreviewed]SubName: Full=Formiminotransferase N-terminal subdomain-containing protein {ECO:0000313|Ensembl:ENSP00000456442}; SubName: Full=HCG1653746, isoform CRA_a {ECO:0000313|EMBL:EAW70185.1};+++[H3BUS8_HUMAN|Unreviewed]SubName: Full=Formiminotransferase N-terminal subdomain-containing protein {ECO:0000313|Ensembl:ENSP00000457780};"]
[35,"'ACADS'",61,53,57,"00280///Valine, leucine and isoleucine degradation+++00071///Fatty acid degradation+++00650///Butanoate metabolism+++01110///Biosynthesis of secondary metabolites+++01200///Carbon metabolism+++01212///Fatty acid metabolism+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways","H00525///Disorders of mitochondrial fatty-acid oxidation+++H01980///SCAD deficiency",null,"R01175///butanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA+++R03172///(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase   (S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor+++R02661///2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase   2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor+++R04751///hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2+++R01178///short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase   Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein","GO:0005759///mitochondrial matrix+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion","GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0016491///oxidoreductase activity+++GO:0003995///acyl-CoA dehydrogenase activity+++GO:0004085///butyryl-CoA dehydrogenase activity+++GO:0050660///flavin adenine dinucleotide binding","GO:0046359///butyrate catabolic process+++GO:0033539///fatty acid beta-oxidation using acyl-CoA dehydrogenase+++GO:0055114///oxidation-reduction process+++GO:0006631///fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006635///fatty acid beta-oxidation","IPR009075///Acyl-CoA dehydrogenase/oxidase C-terminal+++IPR013786///Acyl-CoA dehydrogenase/oxidase, N-terminal+++IPR036250///Acyl-CoA dehydrogenase-like, C-terminal+++IPR006089///Acyl-CoA dehydrogenase, conserved site+++IPR037069///Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily+++IPR006091///Acyl-CoA oxidase/dehydrogenase, central domain+++IPR009100///Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily","[ACADS_HUMAN|Reviewed]RecName: Full=Short-chain specific acyl-CoA dehydrogenase, mitochondrial; Short=SCAD; EC=1.3.8.1; AltName: Full=Butyryl-CoA dehydrogenase; Flags: Precursor;+++[B4DUH1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51323, highly similar to Short-chain specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000313|EMBL:BAG62333.1};+++[D4QEZ8_HUMAN|Unreviewed]SubName: Full=Short-chain acyl-CoA dehydrogenase {ECO:0000313|EMBL:BAJ05798.1};+++[E5KSD5_HUMAN|Unreviewed]SubName: Full=Acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain {ECO:0000313|EMBL:EAW98218.1}; SubName: Full=Mitochondrial short-chain specific acyl-CoA dehydrogenase {ECO:0000313|EMBL:ADP91814.1};+++[E9PE82_HUMAN|Unreviewed]SubName: Full=Short-chain-specific acyl-CoA dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000401045};"]
[353274,"'ZNF445'",151.98,149,150.49,{"$nulls":4},"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box+++IPR003309///SCAN domain+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR038269///SCAN domain superfamily","[ZN445_HUMAN|Reviewed]RecName: Full=Zinc finger protein 445; AltName: Full=Zinc finger protein 168; AltName: Full=Zinc finger protein with KRAB and SCAN domains 15;+++[A0A087X0J9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 445 {ECO:0000313|Ensembl:ENSP00000483454};+++[B7ZKX2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAI43440.1};"]
[353322,"'ANKRD37'",38,33,35.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01817///Beukes hip dysplasia (BHD)",null,null,"GO:0005739///mitochondrion+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0016790///thiolester hydrolase activity+++GO:0071567///UFM1 hydrolase activity","GO:0033146///regulation of intracellular estrogen receptor signaling pathway+++GO:0006508///proteolysis","IPR002110///Ankyrin repeat+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily","[ANR37_HUMAN|Reviewed]RecName: Full=Ankyrin repeat domain-containing protein 37; AltName: Full=Low-density lipoprotein receptor-related protein 2-binding protein; Short=hLrp2bp;+++[B4E066_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50037, highly similar to Ankyrin repeat domain-containing protein 37 {ECO:0000313|EMBL:BAG64328.1};+++[D6RFF5_HUMAN|Unreviewed]SubName: Full=Ankyrin repeat domain-containing protein 37 {ECO:0000313|Ensembl:ENSP00000421529}; Flags: Fragment;"]
[3557,"'IL1RN'",1,1,1,"04060///Cytokine-cytokine receptor interaction","H01275///Interleukin 1 receptor antagonist deficiency (DIRA)+++H00084///Graft-versus-host disease",null,null,"GO:0005622///intracellular+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0031982///vesicle+++GO:0005737///cytoplasm","GO:0005125///cytokine activity+++GO:0005515///protein binding+++GO:0005150///interleukin-1, type I receptor binding+++GO:0005152///interleukin-1 receptor antagonist activity+++GO:0045352///interleukin-1 type I receptor antagonist activity+++GO:0005149///interleukin-1 receptor binding+++GO:0005151///interleukin-1, type II receptor binding+++GO:0045353///interleukin-1 type II receptor antagonist activity","GO:0030073///insulin secretion+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0006955///immune response+++GO:0010469///regulation of signaling receptor activity+++GO:0071222///cellular response to lipopolysaccharide+++GO:0019221///cytokine-mediated signaling pathway+++GO:0006629///lipid metabolic process+++GO:0032755///positive regulation of interleukin-6 production+++GO:0046330///positive regulation of JNK cascade+++GO:0030593///neutrophil chemotaxis+++GO:0051384///response to glucocorticoid+++GO:0001960///negative regulation of cytokine-mediated signaling pathway+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0006954///inflammatory response+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:2000660///negative regulation of interleukin-1-mediated signaling pathway+++GO:0006953///acute-phase response","IPR008996///Cytokine IL1/FGF+++IPR020877///Interleukin-1 conserved site+++IPR000975///Interleukin-1 family+++IPR039348///Interleukin-1 receptor antagonist+++IPR003297///Interleukin-1 receptor antagonist/Interleukin-36","[IL1RA_HUMAN|Reviewed]RecName: Full=Interleukin-1 receptor antagonist protein; Short=IL-1RN; Short=IL-1ra; Short=IRAP; AltName: Full=ICIL-1RA; AltName: Full=IL1 inhibitor; AltName: INN=Anakinra; Flags: Precursor;+++[A0A024R528_HUMAN|Unreviewed]RecName: Full=Interleukin-1 {ECO:0000256|RuleBase:RU003753};+++[Q9UP87_HUMAN|Unreviewed]SubName: Full=Type II interleukin-1 receptor antagonist {ECO:0000313|EMBL:AAC13499.1}; Flags: Fragment;"]
[3590,"'IL11RA'",67,76,71.5,"04640///Hematopoietic cell lineage+++04060///Cytokine-cytokine receptor interaction+++04630///Jak-STAT signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0009897///external side of plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity+++GO:0019955///cytokine binding+++GO:0019970///interleukin-11 binding+++GO:0004921///interleukin-11 receptor activity","GO:0008284///positive regulation of cell proliferation+++GO:0038154///interleukin-11-mediated signaling pathway+++GO:0060322///head development+++GO:0019221///cytokine-mediated signaling pathway+++GO:0032502///developmental process","IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold+++IPR036116///Fibronectin type III superfamily+++IPR003961///Fibronectin type III+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003530///Long hematopoietin receptor, soluble alpha chain, conserved site+++IPR007110///Immunoglobulin-like domain","[I11RA_HUMAN|Reviewed]RecName: Full=Interleukin-11 receptor subunit alpha; Short=IL-11 receptor subunit alpha; Short=IL-11R subunit alpha; Short=IL-11R-alpha; Short=IL-11RA; Flags: Precursor;+++[G3V2A5_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000450543}; Flags: Fragment;+++[G3V2G0_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000450640}; Flags: Fragment;+++[G3V2J5_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000450707};+++[G3V3V2_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000451447}; Flags: Fragment;+++[G3V428_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000451553};+++[G3V571_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000452207}; Flags: Fragment;+++[H0YCS8_HUMAN|Unreviewed]SubName: Full=Interleukin-11 receptor subunit alpha {ECO:0000313|Ensembl:ENSP00000432263}; Flags: Fragment;+++[Q5VZ79_HUMAN|Unreviewed]SubName: Full=HCG2011440, isoform CRA_a {ECO:0000313|EMBL:EAW58422.1}; SubName: Full=cDNA FLJ37370 fis, clone BRAMY2024593, highly similar to Interleukin-11 receptor alpha chain {ECO:0000313|EMBL:BAG52913.1}; SubName: Full=cDNA FLJ78258, highly similar to Homo sapiens interleukin 11 receptor, alpha (IL11RA), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84762.1};"]
[3603,"'IL16'",2,9,5.5,"04060///Cytokine-cytokine receptor interaction","H01357///Allergic contact dermatitis",null,null,"GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005615///extracellular space+++GO:0005634///nucleus","GO:0042609///CD4 receptor binding+++GO:0005125///cytokine activity","GO:0030595///leukocyte chemotaxis+++GO:0050930///induction of positive chemotaxis+++GO:0051924///regulation of calcium ion transport+++GO:0010469///regulation of signaling receptor activity+++GO:0019221///cytokine-mediated signaling pathway+++GO:0016032///viral process+++GO:0006935///chemotaxis+++GO:0006955///immune response","IPR020450///Interleukin-16+++IPR001478///PDZ domain+++IPR036034///PDZ superfamily","[IL16_HUMAN|Reviewed]RecName: Full=Pro-interleukin-16; Contains: RecName: Full=Interleukin-16; Short=IL-16; AltName: Full=Lymphocyte chemoattractant factor; Short=LCF;+++[B3KY62_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135}; Flags: Fragment;+++[B7Z8M3_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135};+++[H0YKB7_HUMAN|Unreviewed]SubName: Full=Pro-interleukin-16 {ECO:0000313|Ensembl:ENSP00000452738};+++[H0YLB1_HUMAN|Unreviewed]SubName: Full=Pro-interleukin-16 {ECO:0000313|Ensembl:ENSP00000453131}; Flags: Fragment;+++[H0YLH9_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135}; Flags: Fragment;+++[H0YLL1_HUMAN|Unreviewed]SubName: Full=Pro-interleukin-16 {ECO:0000313|Ensembl:ENSP00000453250}; Flags: Fragment;+++[H3BN12_HUMAN|Unreviewed]SubName: Full=Pro-interleukin-16 {ECO:0000313|Ensembl:ENSP00000454636}; Flags: Fragment;+++[H3BT15_HUMAN|Unreviewed]SubName: Full=Pro-interleukin-16 {ECO:0000313|Ensembl:ENSP00000456972};+++[I7GGY3_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135};+++[Q05BE6_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135}; Flags: Fragment;+++[Q53HR8_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135}; Flags: Fragment;+++[Q6ZTT5_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135};+++[Q8IUU6_HUMAN|Unreviewed]SubName: Full=IL16 protein {ECO:0000313|EMBL:AAH40272.1};+++[Q9UME6_HUMAN|Unreviewed]RecName: Full=Pro-interleukin-16 {ECO:0000256|RuleBase:RU363135}; Contains: RecName: Full=Interleukin-16 {ECO:0000256|RuleBase:RU363135}; Short=IL-16 {ECO:0000256|RuleBase:RU363135}; AltName: Full=Lymphocyte chemoattractant factor {ECO:0000256|RuleBase:RU363135}; Short=LCF {ECO:0000256|RuleBase:RU363135};"]
[3622,"'ING2'",67,46,56.5,{"$nulls":4},"GO:0016580///Sin3 complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016602///CCAAT-binding factor complex+++GO:0005654///nucleoplasm+++GO:0005794///Golgi apparatus+++GO:0005886///plasma membrane","GO:0044877///protein-containing complex binding+++GO:0035064///methylated histone binding+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0035091///phosphatidylinositol binding","GO:0007141///male meiosis I+++GO:0007165///signal transduction+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0072520///seminiferous tubule development+++GO:0007286///spermatid development+++GO:2000772///regulation of cellular senescence+++GO:0006325///chromatin organization+++GO:0030317///flagellated sperm motility+++GO:0048133///male germ-line stem cell asymmetric division+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0006351///transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0031065///positive regulation of histone deacetylation+++GO:0040008///regulation of growth+++GO:1902166///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0008285///negative regulation of cell proliferation+++GO:0007283///spermatogenesis","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR024610///Inhibitor of growth protein, N-terminal histone-binding+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR001965///Zinc finger, PHD-type+++IPR028639///Inhibitor of growth protein 2+++IPR019787///Zinc finger, PHD-finger","[ING2_HUMAN|Reviewed]RecName: Full=Inhibitor of growth protein 2; AltName: Full=Inhibitor of growth 1-like protein; Short=ING1Lp; AltName: Full=p32; AltName: Full=p33ING2;+++[B2RA15_HUMAN|Unreviewed]RecName: Full=Inhibitor of growth protein {ECO:0000256|RuleBase:RU361213};"]
[3646,"'EIF3E'",997,1133,1065,"05160///Hepatitis C+++03013///RNA transport",{"$nulls":3},"GO:0000785///chromatin+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005829///cytosol+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0071540///eukaryotic translation initiation factor 3 complex, eIF3e+++GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0033290///eukaryotic 48S preinitiation complex+++GO:0070062///extracellular exosome","GO:0047485///protein N-terminus binding+++GO:0003743///translation initiation factor activity+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0003723///RNA binding","GO:1902416///positive regulation of mRNA binding+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0045947///negative regulation of translational initiation+++GO:0045727///positive regulation of translation+++GO:0006413///translational initiation+++GO:0006446///regulation of translational initiation+++GO:0006412///translation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0002183///cytoplasmic translational initiation","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR000717///Proteasome component (PCI) domain+++IPR019010///Eukaryotic translation initiation factor 3 subunit E, N-terminal+++IPR016650///Eukaryotic translation initiation factor 3 subunit E","[EIF3E_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000255|HAMAP-Rule:MF_03004}; Short=eIF3e {ECO:0000255|HAMAP-Rule:MF_03004}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 6 {ECO:0000255|HAMAP-Rule:MF_03004}; AltName: Full=Viral integration site protein INT-6 homolog; AltName: Full=eIF-3 p48 {ECO:0000255|HAMAP-Rule:MF_03004};+++[A0A161SXE1_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E isoform 2 transcript variant {ECO:0000313|EMBL:AGW27411.1};+++[B2R806_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000256|HAMAP-Rule:MF_03004, ECO:0000256|PIRNR:PIRNR016255}; Short=eIF3e {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 6 {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=eIF-3 p48 {ECO:0000256|HAMAP-Rule:MF_03004};+++[B3KW56_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000256|HAMAP-Rule:MF_03004, ECO:0000256|PIRNR:PIRNR016255}; Short=eIF3e {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 6 {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=eIF-3 p48 {ECO:0000256|HAMAP-Rule:MF_03004};+++[E5RGA2_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000256|HAMAP-Rule:MF_03004, ECO:0000256|PIRNR:PIRNR016255}; Short=eIF3e {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 6 {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=eIF-3 p48 {ECO:0000256|HAMAP-Rule:MF_03004};+++[E5RHS5_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000430839}; Flags: Fragment;+++[E5RII3_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000430709};+++[E5RIP5_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000429327};+++[E5RIT4_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000430678}; Flags: Fragment;+++[E5RJ25_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000430649};+++[H0YAW4_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000428170}; Flags: Fragment;+++[H0YBP5_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000429968}; Flags: Fragment;+++[H0YBR5_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000313|Ensembl:ENSP00000430152}; Flags: Fragment;+++[Q6IAX5_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit E {ECO:0000256|HAMAP-Rule:MF_03004, ECO:0000256|PIRNR:PIRNR016255}; Short=eIF3e {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 6 {ECO:0000256|HAMAP-Rule:MF_03004}; AltName: Full=eIF-3 p48 {ECO:0000256|HAMAP-Rule:MF_03004};"]
[3669,"'ISG20'",78,89,83.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016605///PML body+++GO:0005634///nucleus+++GO:0015030///Cajal body+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0016787///hydrolase activity+++GO:0034511///U3 snoRNA binding+++GO:0000175///3'-5'-exoribonuclease activity+++GO:0046872///metal ion binding+++GO:0030620///U2 snRNA binding+++GO:0004527///exonuclease activity+++GO:0008859///exoribonuclease II activity+++GO:0030619///U1 snRNA binding+++GO:0004518///nuclease activity","GO:0090503///RNA phosphodiester bond hydrolysis, exonucleolytic+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0008283///cell proliferation+++GO:0045071///negative regulation of viral genome replication+++GO:0002376///immune system process+++GO:0000738///DNA catabolic process, exonucleolytic+++GO:0060337///type I interferon signaling pathway+++GO:0006401///RNA catabolic process+++GO:0045087///innate immune response+++GO:0009615///response to virus+++GO:0006364///rRNA processing+++GO:0051607///defense response to virus","IPR012337///Ribonuclease H-like superfamily+++IPR036397///Ribonuclease H superfamily+++IPR013520///Exonuclease, RNase T/DNA polymerase III","[ISG20_HUMAN|Reviewed]RecName: Full=Interferon-stimulated gene 20 kDa protein; EC=3.1.13.1; AltName: Full=Estrogen-regulated transcript 45 protein; AltName: Full=Promyelocytic leukemia nuclear body-associated protein ISG20;+++[A0A024RC76_HUMAN|Unreviewed]SubName: Full=Interferon stimulated exonuclease gene 20kDa, isoform CRA_a {ECO:0000313|EMBL:EAX02016.1};+++[H0YMM4_HUMAN|Unreviewed]SubName: Full=Interferon-stimulated gene 20 kDa protein {ECO:0000313|Ensembl:ENSP00000453666}; Flags: Fragment;+++[H3BLY5_HUMAN|Unreviewed]SubName: Full=Interferon-stimulated gene 20 kDa protein {ECO:0000313|Ensembl:ENSP00000368526};"]
[3687,"'ITGAX'",5.01,1,3.005,"04810///Regulation of actin cytoskeleton+++04610///Complement and coagulation cascades+++05152///Tuberculosis",{"$nulls":3},"GO:0101003///ficolin-1-rich granule membrane+++GO:0070821///tertiary granule membrane+++GO:0009986///cell surface+++GO:0009897///external side of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0008305///integrin complex+++GO:0030667///secretory granule membrane+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0046872///metal ion binding","GO:0007229///integrin-mediated signaling pathway+++GO:0030198///extracellular matrix organization+++GO:0043312///neutrophil degranulation+++GO:0034113///heterotypic cell-cell adhesion+++GO:0050900///leukocyte migration+++GO:0019221///cytokine-mediated signaling pathway+++GO:0007155///cell adhesion+++GO:0051607///defense response to virus+++GO:0009887///animal organ morphogenesis","IPR028994///Integrin alpha, N-terminal+++IPR018184///Integrin alpha chain, C-terminal cytoplasmic region, conserved site+++IPR000413///Integrin alpha chain+++IPR013517///FG-GAP repeat+++IPR013649///Integrin alpha-2+++IPR002035///von Willebrand factor, type A+++IPR032695///Integrin domain superfamily+++IPR013519///Integrin alpha beta-propellor+++IPR036465///von Willebrand factor A-like domain superfamily","[ITAX_HUMAN|Reviewed]RecName: Full=Integrin alpha-X; AltName: Full=CD11 antigen-like family member C; AltName: Full=Leu M5; AltName: Full=Leukocyte adhesion glycoprotein p150,95 alpha chain; AltName: Full=Leukocyte adhesion receptor p150,95; AltName: CD_antigen=CD11c; Flags: Precursor;+++[A0A087X131_HUMAN|Unreviewed]SubName: Full=Integrin alpha-X {ECO:0000313|Ensembl:ENSP00000483860};+++[H3BN02_HUMAN|Unreviewed]SubName: Full=Integrin alpha-X {ECO:0000313|Ensembl:ENSP00000454623};"]
[3704,"'ITPA'",379,233,306,"00983///Drug metabolism - other enzymes+++01100///Metabolic pathways+++00230///Purine metabolism","H00606///Early infantile epileptic encephalopathy",null,"R03531///2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase; dITP   dITP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Diphosphate+++R08243///inosine triphosphate pyrophosphatase   6-Mercaptopurine ribonucleoside triphosphate + H2O <=> 6-Thioinosine-5'-monophosphate + Diphosphate+++R00426///GTP diphosphohydrolase (diphosphate-forming); Guanosine   GTP + H2O <=> GMP + Diphosphate+++R00720///Inosine 5'-triphosphate pyrophosphohydrolase   ITP + H2O <=> IMP + Diphosphate+++R01855///2'-Deoxyguanosine 5'-triphosphate diphosphohydrolase   dGTP + H2O <=> dGMP + Diphosphate+++R02720///XTP pyrophosphohydrolase; XTP   XTP + H2O <=> Xanthosine 5'-phosphate + Diphosphate+++R02100///dUTP nucleotidohydrolase   dUTP + H2O <=> dUMP + Diphosphate","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0004551///nucleotide diphosphatase activity+++GO:0035870///dITP diphosphatase activity+++GO:0042802///identical protein binding+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0035529///NADH pyrophosphatase activity+++GO:0036220///ITP diphosphatase activity+++GO:0046872///metal ion binding+++GO:0036222///XTP diphosphatase activity","GO:0051276///chromosome organization+++GO:0009143///nucleoside triphosphate catabolic process+++GO:0009117///nucleotide metabolic process+++GO:0006195///purine nucleotide catabolic process+++GO:0006193///ITP catabolic process+++GO:0009204///deoxyribonucleoside triphosphate catabolic process","IPR002637///Ham1-like protein+++IPR027502///Inosine triphosphate pyrophosphatase+++IPR029001///Inosine triphosphate pyrophosphatase-like","[ITPA_HUMAN|Reviewed]RecName: Full=Inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Short=ITPase {ECO:0000255|HAMAP-Rule:MF_03148}; Short=Inosine triphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; EC=3.6.1.9 {ECO:0000255|HAMAP-Rule:MF_03148, ECO:0000269|PubMed:17090528}; AltName: Full=Non-canonical purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; AltName: Full=Non-standard purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; AltName: Full=Nucleoside-triphosphate diphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; AltName: Full=Nucleoside-triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Short=NTPase {ECO:0000255|HAMAP-Rule:MF_03148}; AltName: Full=Putative oncogene protein hlc14-06-p;+++[A0A0S2Z3W7_HUMAN|Unreviewed]RecName: Full=Nucleotide diphosphatase {ECO:0000256|SAAS:SAAS00721536}; EC=3.6.1.9 {ECO:0000256|SAAS:SAAS00721536}; Flags: Fragment;+++[A0A0S2Z423_HUMAN|Unreviewed]RecName: Full=Nucleotide diphosphatase {ECO:0000256|SAAS:SAAS00721536}; EC=3.6.1.9 {ECO:0000256|SAAS:SAAS00721536}; Flags: Fragment;+++[Q5NT82_HUMAN|Unreviewed]SubName: Full=ITPase {ECO:0000313|EMBL:BAD81025.1}; Flags: Fragment;+++[Q8WWI0_HUMAN|Unreviewed]SubName: Full=Putative oncogene GK005 {ECO:0000313|EMBL:AAL57168.1};"]
[372,"'ARCN1'",3848,4644,4246,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0030137///COPI-coated vesicle+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0030133///transport vesicle+++GO:0030126///COPI vesicle coat+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0030663///COPI-coated vesicle membrane","GO:0003723///RNA binding","GO:0008344///adult locomotory behavior+++GO:0043473///pigmentation+++GO:0048193///Golgi vesicle transport+++GO:0015031///protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0006886///intracellular protein transport+++GO:0021691///cerebellar Purkinje cell layer maturation+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0016192///vesicle-mediated transport+++GO:0051645///Golgi localization","IPR027059///Coatomer delta subunit+++IPR011012///Longin-like domain superfamily+++IPR022775///AP complex, mu/sigma subunit+++IPR036168///AP-2 complex subunit mu, C-terminal superfamily+++IPR028565///Mu homology domain","[COPD_HUMAN|Reviewed]RecName: Full=Coatomer subunit delta; AltName: Full=Archain; AltName: Full=Delta-coat protein; Short=Delta-COP;+++[B0YIW5_HUMAN|Unreviewed]RecName: Full=Coatomer subunit delta {ECO:0000256|RuleBase:RU364018};+++[B0YIW6_HUMAN|Unreviewed]SubName: Full=Archain 1, isoform CRA_a {ECO:0000313|EMBL:EAW67397.1}; SubName: Full=Coatomer subunit delta variant 2 {ECO:0000313|EMBL:ACA05944.1};+++[E9PK34_HUMAN|Unreviewed]RecName: Full=Coatomer subunit delta {ECO:0000256|RuleBase:RU364018};+++[Q6P1Q5_HUMAN|Unreviewed]RecName: Full=Coatomer subunit delta {ECO:0000256|RuleBase:RU364018};"]
[374,"'AREG'",3,3,3,"04390///Hippo signaling pathway+++05210///Colorectal cancer+++04012///ErbB signaling pathway+++04151///PI3K-Akt signaling pathway+++04010///MAPK signaling pathway","H00020///Colorectal cancer",null,null,"GO:0000790///nuclear chromatin+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005634///nucleus+++GO:0009986///cell surface+++GO:0016607///nuclear speck+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016021///integral component of membrane","GO:0005497///androgen binding+++GO:0046983///protein dimerization activity+++GO:0005154///epidermal growth factor receptor binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0051117///ATPase binding+++GO:0043565///sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0005496///steroid binding+++GO:0070974///POU domain binding+++GO:0003707///steroid hormone receptor activity+++GO:0004882///androgen receptor activity+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0019899///enzyme binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005102///signaling receptor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0008270///zinc ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0001091///RNA polymerase II basal transcription factor binding+++GO:0008083///growth factor activity+++GO:0008289///lipid binding+++GO:0008013///beta-catenin binding+++GO:0005125///cytokine activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0004879///nuclear receptor activity","GO:0031175///neuron projection development+++GO:0043410///positive regulation of MAPK cascade+++GO:0014070///response to organic cyclic compound+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0006351///transcription, DNA-templated+++GO:0014009///glial cell proliferation+++GO:0008283///cell proliferation+++GO:0019102///male somatic sex determination+++GO:0007338///single fertilization+++GO:0060520///activation of prostate induction by androgen receptor signaling pathway+++GO:0007548///sex differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0043434///response to peptide hormone+++GO:0008584///male gonad development+++GO:0010628///positive regulation of gene expression+++GO:0060598///dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0009566///fertilization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060736///prostate gland growth+++GO:0048808///male genitalia morphogenesis+++GO:0007283///spermatogenesis+++GO:0048608///reproductive structure development+++GO:0060742///epithelial cell differentiation involved in prostate gland development+++GO:0050790///regulation of catalytic activity+++GO:0016579///protein deubiquitination+++GO:0042542///response to hydrogen peroxide+++GO:0048638///regulation of developmental growth+++GO:0060749///mammary gland alveolus development+++GO:0060685///regulation of prostatic bud formation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0048645///animal organ formation+++GO:0010469///regulation of signaling receptor activity+++GO:0060750///epithelial cell proliferation involved in mammary gland duct elongation+++GO:0003382///epithelial cell morphogenesis+++GO:1903076///regulation of protein localization to plasma membrane+++GO:0051259///protein complex oligomerization+++GO:0048208///COPII vesicle coating+++GO:0030521///androgen receptor signaling pathway+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060744///mammary gland branching involved in thelarche+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0032355///response to estradiol+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0003073///regulation of systemic arterial blood pressure+++GO:0060769///positive regulation of epithelial cell proliferation involved in prostate gland development+++GO:0071383///cellular response to steroid hormone stimulus+++GO:0051591///response to cAMP+++GO:0009987///cellular process+++GO:0060740///prostate gland epithelium morphogenesis+++GO:0033327///Leydig cell differentiation+++GO:0042327///positive regulation of phosphorylation+++GO:0060599///lateral sprouting involved in mammary gland duct morphogenesis+++GO:0008285///negative regulation of cell proliferation+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0061458///reproductive system development+++GO:0030850///prostate gland development+++GO:0060571///morphogenesis of an epithelial fold+++GO:0035264///multicellular organism growth+++GO:0043568///positive regulation of insulin-like growth factor receptor signaling pathway+++GO:0045726///positive regulation of integrin biosynthetic process+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0008284///positive regulation of cell proliferation+++GO:0033148///positive regulation of intracellular estrogen receptor signaling pathway+++GO:0001701///in utero embryonic development+++GO:0045597///positive regulation of cell differentiation+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:0010468///regulation of gene expression+++GO:0007267///cell-cell signaling+++GO:0030522///intracellular receptor signaling pathway+++GO:0072520///seminiferous tubule development+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0071394///cellular response to testosterone stimulus+++GO:0045720///negative regulation of integrin biosynthetic process+++GO:0051384///response to glucocorticoid+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007165///signal transduction","IPR013032///EGF-like, conserved site+++IPR015497///Epidermal growth factor receptor ligand+++IPR000742///EGF-like domain","[AREG_HUMAN|Reviewed]RecName: Full=Amphiregulin {ECO:0000303|PubMed:2325643}; Short=AR {ECO:0000303|PubMed:2325643}; AltName: Full=Colorectum cell-derived growth factor {ECO:0000303|PubMed:1333777}; Short=CRDGF {ECO:0000303|PubMed:1333777}; Flags: Precursor;+++[A0A087WZ66_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|Ensembl:ENSP00000482407};+++[A0A087X1B6_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|Ensembl:ENSP00000484033};+++[C0JKD5_HUMAN|Unreviewed]SubName: Full=Androgen receptor splice variant 4b {ECO:0000313|EMBL:ACN39561.1};+++[C0JKD6_HUMAN|Unreviewed]SubName: Full=Androgen receptor splice variant 5 {ECO:0000313|EMBL:ACN39562.1};+++[C0JKD7_HUMAN|Unreviewed]SubName: Full=Androgen receptor splice variant 6 {ECO:0000313|EMBL:ACN39563.1};+++[D2KF13_HUMAN|Unreviewed]SubName: Full=Androgen receptor variant 5,6,7es {ECO:0000313|EMBL:ACZ81436.1};+++[D2Y6K2_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform 1 transcript variant 1 {ECO:0000313|EMBL:ADB54358.1};+++[D3YPP9_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform 1 transcript variant 1 {ECO:0000313|EMBL:ADD26777.1};+++[D3YPQ0_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform 1 transcript variant 1 {ECO:0000313|EMBL:ADD26778.1};+++[D3YPQ1_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform 1 transcript variant 1 {ECO:0000313|EMBL:ADD26779.1};+++[D3YPQ2_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform 1 transcript variant 1 {ECO:0000313|EMBL:ADD26780.1};+++[D3YPQ3_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform 1 transcript variant 1 {ECO:0000313|EMBL:ADD26781.1};+++[D5M8Q2_HUMAN|Unreviewed]SubName: Full=Mutant androgen receptor isoform 1 transcript variant 1 {ECO:0000313|EMBL:ADF47187.1};+++[D6RFX5_HUMAN|Unreviewed]SubName: Full=Amphiregulin {ECO:0000313|Ensembl:ENSP00000421414};+++[E9PEG3_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|Ensembl:ENSP00000425199};+++[F5GZG9_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|Ensembl:ENSP00000379359};+++[Q13771_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|EMBL:AAA51735.1};+++[Q9UKJ6_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|EMBL:AAF04001.1}; Flags: Fragment;+++[V9GZH8_HUMAN|Unreviewed]SubName: Full=AR protein {ECO:0000313|EMBL:AAA51778.1};+++[V9TLK5_HUMAN|Unreviewed]SubName: Full=Androgen receptor {ECO:0000313|EMBL:AHC70787.1}; Flags: Fragment;+++[X5DNC5_HUMAN|Unreviewed]SubName: Full=Androgen receptor isoform A {ECO:0000313|EMBL:AHW56411.1}; Flags: Fragment;"]
[374618,"'TEX9'",135,137,136,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,null,"[TEX9_HUMAN|Reviewed]RecName: Full=Testis-expressed protein 9;+++[A0A0S2Z5Z9_HUMAN|Unreviewed]SubName: Full=Testis expressed 9 isoform 5 {ECO:0000313|EMBL:ALQ34362.1}; Flags: Fragment;+++[A0A0S2Z669_HUMAN|Unreviewed]SubName: Full=Testis expressed 9 isoform 1 {ECO:0000313|EMBL:ALQ34360.1}; Flags: Fragment;+++[A0A0S2Z6S1_HUMAN|Unreviewed]SubName: Full=Testis expressed 9 isoform 4 {ECO:0000313|EMBL:ALQ34361.1};+++[H0YKG1_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 9 {ECO:0000313|Ensembl:ENSP00000452791}; Flags: Fragment;+++[H0YLZ3_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 9 {ECO:0000313|Ensembl:ENSP00000453398};+++[H0YM20_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 9 {ECO:0000313|Ensembl:ENSP00000453431};+++[H0YND2_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 9 {ECO:0000313|Ensembl:ENSP00000453960};+++[H3BS88_HUMAN|Unreviewed]SubName: Full=Testis-expressed protein 9 {ECO:0000313|Ensembl:ENSP00000456593};"]
[374879,"'ZNF699'",53.93,129.99,91.96,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box","[ZN699_HUMAN|Reviewed]RecName: Full=Zinc finger protein 699; AltName: Full=Hangover homolog;"]
[375,"'ARF1'",9186,7011,8098.5,"05134///Legionellosis+++05110///Vibrio cholerae infection+++04072///Phospholipase D signaling pathway+++04144///Endocytosis",{"$nulls":3},"GO:0014069///postsynaptic density+++GO:0005802///trans-Golgi network+++GO:0005886///plasma membrane+++GO:0031252///cell leading edge+++GO:0005925///focal adhesion+++GO:0005770///late endosome+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0030017///sarcomere+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0030137///COPI-coated vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0045211///postsynaptic membrane+++GO:0005778///peroxisomal membrane+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection","GO:1990583///phospholipase D activator activity+++GO:0019904///protein domain specific binding+++GO:0000287///magnesium ion binding+++GO:0003723///RNA binding+++GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0046982///protein heterodimerization activity+++GO:0003924///GTPase activity","GO:0034315///regulation of Arp2/3 complex-mediated actin nucleation+++GO:0006878///cellular copper ion homeostasis+++GO:0002090///regulation of receptor internalization+++GO:0015031///protein transport+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:1902824///positive regulation of late endosome to lysosome transport+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:1902307///positive regulation of sodium ion transmembrane transport+++GO:0097212///lysosomal membrane organization+++GO:0070142///synaptic vesicle budding+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:1990386///mitotic cleavage furrow ingression+++GO:0050714///positive regulation of protein secretion+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0007015///actin filament organization+++GO:0097061///dendritic spine organization+++GO:0098586///cellular response to virus+++GO:1903725///regulation of phospholipid metabolic process+++GO:1902953///positive regulation of ER to Golgi vesicle-mediated transport+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0060292///long-term synaptic depression+++GO:0045807///positive regulation of endocytosis+++GO:0055108///Golgi to transport vesicle transport+++GO:0050690///regulation of defense response to virus by virus+++GO:0060999///positive regulation of dendritic spine development","IPR006689///Small GTPase superfamily, ARF/SAR type+++IPR005225///Small GTP-binding protein domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[ARF1_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor 1;+++[A0A024R3Q3_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW69836.1};"]
[375341,"'C3orf62'",56,60.01,58.005,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"IPR031670///Protein of unknown function DUF4712","[CC062_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C3orf62;+++[C9JW57_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C3orf62 {ECO:0000313|Ensembl:ENSP00000413663}; Flags: Fragment;+++[H7BZX3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C3orf62 {ECO:0000313|Ensembl:ENSP00000391945}; Flags: Fragment;"]
[375743,"'PTAR1'",259,498,378.5,{"$nulls":4},"GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0008318///protein prenyltransferase activity+++GO:0004659///prenyltransferase activity","GO:0018342///protein prenylation","IPR002088///Protein prenyltransferase, alpha subunit","[PTAR1_HUMAN|Reviewed]RecName: Full=Protein prenyltransferase alpha subunit repeat-containing protein 1;+++[F5GXY1_HUMAN|Unreviewed]SubName: Full=Protein prenyltransferase alpha subunit repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000440164};+++[J3KQP8_HUMAN|Unreviewed]SubName: Full=Protein prenyltransferase alpha subunit repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000405943}; Flags: Fragment;+++[X6R9N0_HUMAN|Unreviewed]SubName: Full=Protein prenyltransferase alpha subunit repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000366405};"]
[3766,"'KCNJ10'",0,4,2,"04971///Gastric acid secretion","H00803///Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME)",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0098793///presynapse+++GO:0016323///basolateral plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005524///ATP binding+++GO:0015467///G-protein activated inward rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0015272///ATP-activated inward rectifier potassium channel activity+++GO:0005267///potassium channel activity+++GO:0005515///protein binding+++GO:0005242///inward rectifier potassium channel activity+++GO:0000166///nucleotide binding","GO:0007628///adult walking behavior+++GO:0055075///potassium ion homeostasis+++GO:0007601///visual perception+++GO:0071805///potassium ion transmembrane transport+++GO:0034220///ion transmembrane transport+++GO:0022010///central nervous system myelination+++GO:0006813///potassium ion transport+++GO:0014003///oligodendrocyte development+++GO:0051935///glutamate reuptake+++GO:0034765///regulation of ion transmembrane transport+++GO:0006811///ion transport+++GO:0060075///regulation of resting membrane potential+++GO:0042391///regulation of membrane potential+++GO:1990573///potassium ion import across plasma membrane+++GO:0048169///regulation of long-term neuronal synaptic plasticity","IPR014756///Immunoglobulin E-set+++IPR013518///Potassium channel, inwardly rectifying, Kir, cytoplasmic+++IPR003269///Potassium channel, inwardly rectifying, Kir1.2+++IPR016449///Potassium channel, inwardly rectifying, Kir","[KCJ10_HUMAN|Reviewed]RecName: Full=ATP-sensitive inward rectifier potassium channel 10; AltName: Full=ATP-dependent inwardly rectifying potassium channel Kir4.1; AltName: Full=Inward rectifier K(+) channel Kir1.2; AltName: Full=Potassium channel, inwardly rectifying subfamily J member 10;+++[A0A1B0GUX2_HUMAN|Unreviewed]SubName: Full=ATP-sensitive inward rectifier potassium channel 10 {ECO:0000313|Ensembl:ENSP00000490282};+++[A0A1W2PP51_HUMAN|Unreviewed]SubName: Full=ATP-sensitive inward rectifier potassium channel 10 {ECO:0000313|Ensembl:ENSP00000491337}; Flags: Fragment;+++[A0A1W2PP61_HUMAN|Unreviewed]SubName: Full=ATP-sensitive inward rectifier potassium channel 10 {ECO:0000313|Ensembl:ENSP00000491175}; Flags: Fragment;+++[A0A1W2PPI0_HUMAN|Unreviewed]SubName: Full=ATP-sensitive inward rectifier potassium channel 10 {ECO:0000313|Ensembl:ENSP00000491416}; Flags: Fragment;+++[A0A1W2PQC0_HUMAN|Unreviewed]SubName: Full=ATP-sensitive inward rectifier potassium channel 10 {ECO:0000313|Ensembl:ENSP00000491635};+++[A0A1W2PQP0_HUMAN|Unreviewed]SubName: Full=ATP-sensitive inward rectifier potassium channel 10 {ECO:0000313|Ensembl:ENSP00000492249}; Flags: Fragment;+++[Q547K1_HUMAN|Unreviewed]SubName: Full=Potassium inwardly-rectifying channel {ECO:0000313|EMBL:AAL89708.1};+++[Q9BXC5_HUMAN|Unreviewed]SubName: Full=Inwardly-rectifying potassium channel Kir1.2 {ECO:0000313|EMBL:AAK27517.1}; Flags: Fragment;"]
[378,"'ARF4'",6670,6050,6360,{"$nulls":4},"GO:0098978///glutamatergic synapse+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0032587///ruffle membrane+++GO:0016020///membrane+++GO:0043197///dendritic spine+++GO:0005829///cytosol+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0005154///epidermal growth factor receptor binding+++GO:0003924///GTPase activity+++GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0060996///dendritic spine development+++GO:0043066///negative regulation of apoptotic process+++GO:0099175///regulation of postsynapse organization+++GO:0016477///cell migration+++GO:0016192///vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0007612///learning+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0007420///brain development+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0050807///regulation of synapse organization+++GO:0045176///apical protein localization+++GO:0015031///protein transport+++GO:0061512///protein localization to cilium+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:0031584///activation of phospholipase D activity+++GO:0006893///Golgi to plasma membrane transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0048678///response to axon injury+++GO:0045197///establishment or maintenance of epithelial cell apical/basal polarity+++GO:0006471///protein ADP-ribosylation","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR005225///Small GTP-binding protein domain+++IPR006689///Small GTPase superfamily, ARF/SAR type","[ARF4_HUMAN|Reviewed]RecName: Full=ADP-ribosylation factor 4;+++[C9J6P1_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 4 {ECO:0000313|Ensembl:ENSP00000418388}; Flags: Fragment;+++[C9JAK5_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 4 {ECO:0000313|Ensembl:ENSP00000417501};+++[C9JPM4_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 4 {ECO:0000313|Ensembl:ENSP00000420254}; Flags: Fragment;+++[F8WDB3_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 4 {ECO:0000313|Ensembl:ENSP00000420655};+++[U3KQF2_HUMAN|Unreviewed]SubName: Full=ADP-ribosylation factor 4 {ECO:0000313|Ensembl:ENSP00000475828};"]
[3795,"'KHK'",12,4,8,"00051///Fructose and mannose metabolism+++01100///Metabolic pathways+++01120///Microbial metabolism in diverse environments",null,null,"R03819///ATP:sedoheptulose 1-phosphotransferase   ATP + Sedoheptulose <=> ADP + Sedoheptulose 1-phosphate+++R00866///ATP:D-fructose 1-phosphotransferase   ATP + D-Fructose <=> ADP + D-Fructose 1-phosphate","GO:0005737///cytoplasm+++GO:0070062///extracellular exosome+++GO:0005829///cytosol","GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004454///ketohexokinase activity+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0019200///carbohydrate kinase activity+++GO:0005524///ATP binding","GO:0009749///response to glucose+++GO:0016310///phosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0032868///response to insulin+++GO:0006000///fructose metabolic process+++GO:0070873///regulation of glycogen metabolic process+++GO:0010043///response to zinc ion+++GO:0046835///carbohydrate phosphorylation+++GO:0009744///response to sucrose+++GO:0061624///fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate+++GO:0009750///response to fructose","IPR029056///Ribokinase-like+++IPR011611///Carbohydrate kinase PfkB+++IPR034093///Ketohexokinase","[KHK_HUMAN|Reviewed]RecName: Full=Ketohexokinase {ECO:0000312|HGNC:HGNC:6315}; EC=2.7.1.3 {ECO:0000269|PubMed:12941785}; AltName: Full=Hepatic fructokinase;+++[A0A140VJM6_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 102 {ECO:0000313|EMBL:AEE61013.1};+++[C9JDL1_HUMAN|Unreviewed]SubName: Full=Ketohexokinase {ECO:0000313|Ensembl:ENSP00000404741}; Flags: Fragment;"]
[3827,"'KNG1'",0,1,0.5,"04610///Complement and coagulation cascades",{"$nulls":3},"GO:0005576///extracellular region+++GO:0031093///platelet alpha granule lumen+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0062023///collagen-containing extracellular matrix+++GO:0070062///extracellular exosome+++GO:0005788///endoplasmic reticulum lumen+++GO:0072562///blood microparticle","GO:0005515///protein binding+++GO:0030414///peptidase inhibitor activity+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0005102///signaling receptor binding+++GO:0008201///heparin binding+++GO:0008270///zinc ion binding","GO:0043687///post-translational protein modification+++GO:0044267///cellular protein metabolic process+++GO:0007597///blood coagulation, intrinsic pathway+++GO:0010951///negative regulation of endopeptidase activity+++GO:0043065///positive regulation of apoptotic process+++GO:0007596///blood coagulation+++GO:0045861///negative regulation of proteolysis+++GO:0042311///vasodilation+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0050880///regulation of blood vessel size+++GO:0002576///platelet degranulation+++GO:0006954///inflammatory response+++GO:0007599///hemostasis+++GO:0010466///negative regulation of peptidase activity+++GO:0030195///negative regulation of blood coagulation+++GO:0007162///negative regulation of cell adhesion+++GO:0007204///positive regulation of cytosolic calcium ion concentration","IPR002395///HMW kininogen+++IPR000010///Cystatin domain+++IPR027358///Kininogen-type cystatin domain+++IPR018073///Proteinase inhibitor I25, cystatin, conserved site","[KNG1_HUMAN|Reviewed]RecName: Full=Kininogen-1; AltName: Full=Alpha-2-thiol proteinase inhibitor; AltName: Full=Fitzgerald factor; AltName: Full=High molecular weight kininogen; Short=HMWK; AltName: Full=Williams-Fitzgerald-Flaujeac factor; Contains: RecName: Full=Kininogen-1 heavy chain; Contains: RecName: Full=T-kinin; AltName: Full=Ile-Ser-Bradykinin; Contains: RecName: Full=Bradykinin; AltName: Full=Kallidin I; Contains: RecName: Full=Lysyl-bradykinin; AltName: Full=Kallidin II; Contains: RecName: Full=Kininogen-1 light chain; Contains: RecName: Full=Low molecular weight growth-promoting factor; Flags: Precursor;+++[B4E1C2_HUMAN|Unreviewed]SubName: Full=Kininogen 1, isoform CRA_b {ECO:0000313|EMBL:EAW78180.1}; SubName: Full=cDNA FLJ56836, highly similar to Kininogen-1 {ECO:0000313|EMBL:BAG64734.1};+++[D3DNU8_HUMAN|Unreviewed]SubName: Full=Kininogen 1, isoform CRA_a {ECO:0000313|EMBL:EAW78181.1};+++[Q05CF8_HUMAN|Unreviewed]SubName: Full=KNG1 protein {ECO:0000313|EMBL:AAH26253.1};"]
[3846,"'KRTAP5-9'",2,2,2,{"$nulls":4},"GO:0045095///keratin filament+++GO:0005829///cytosol",null,"GO:0031424///keratinization+++GO:0008544///epidermis development","IPR002494///Keratin-associated protein","[KRA59_HUMAN|Reviewed]RecName: Full=Keratin-associated protein 5-9; AltName: Full=Keratin, cuticle, ultrahigh sulfur 1; AltName: Full=Keratin, ultra high-sulfur matrix protein A; AltName: Full=Keratin-associated protein 5.9; AltName: Full=UHS keratin A; Short=UHS KerA; AltName: Full=Ultrahigh sulfur keratin-associated protein 5.9;"]
[387104,"'SOGA3'",41.2,60.36,50.78,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0016021///integral component of membrane",null,"GO:0010506///regulation of autophagy","IPR027881///Protein SOGA","[SOGA3_HUMAN|Reviewed]RecName: Full=Protein SOGA3; Flags: Precursor;+++[A0A1D5RMT3_HUMAN|Unreviewed]SubName: Full=Protein SOGA3 {ECO:0000313|Ensembl:ENSP00000431662}; Flags: Fragment;+++[A1L177_HUMAN|Unreviewed]SubName: Full=C6orf174 protein {ECO:0000313|EMBL:AAI27761.1}; Flags: Fragment;+++[A5PLQ8_HUMAN|Unreviewed]SubName: Full=C6orf174 protein {ECO:0000313|EMBL:AAI43044.1}; Flags: Fragment;+++[E9PJP2_HUMAN|Unreviewed]SubName: Full=Protein SOGA3 {ECO:0000313|Ensembl:ENSP00000435559};"]
[387712,"'ENO4'",7,10,8.5,"01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways+++04066///HIF-1 signaling pathway+++01130///Biosynthesis of antibiotics+++01230///Biosynthesis of amino acids+++00680///Methane metabolism+++00010///Glycolysis / Gluconeogenesis+++03018///RNA degradation+++01200///Carbon metabolism+++01110///Biosynthesis of secondary metabolites","H00069///Glycogen storage diseases (GSD)+++H01762///Muscle glycogen storage disease+++H01953///Glycogen storage disease type XIII","M00346///Formaldehyde assimilation, serine pathway+++M00002///Glycolysis, core module involving three-carbon compounds+++M00003///Gluconeogenesis, oxaloacetate => fructose-6P+++M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate+++M00394///RNA degradosome","R00658///2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)   2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O","GO:0000015///phosphopyruvate hydratase complex+++GO:0005575///cellular_component","GO:0016829///lyase activity+++GO:0000287///magnesium ion binding+++GO:0003674///molecular_function+++GO:0004634///phosphopyruvate hydratase activity","GO:0006096///glycolytic process+++GO:0008150///biological_process","IPR029017///Enolase-like, N-terminal+++IPR020810///Enolase, C-terminal TIM barrel domain+++IPR036849///Enolase-like, C-terminal domain superfamily+++IPR020811///Enolase, N-terminal+++IPR000941///Enolase","[ENO4_HUMAN|Reviewed]RecName: Full=Enolase 4; EC=4.2.1.11; AltName: Full=2-phospho-D-glycerate hydro-lyase;+++[S4R3X7_HUMAN|Unreviewed]SubName: Full=Enolase 4 {ECO:0000313|Ensembl:ENSP00000474839}; Flags: Fragment;"]
[3880,"'KRT19'",17583,12677,15130,"04915///Estrogen signaling pathway","H00723///Non-epidermolytic palmoplantar keratoderma (NEPPK)+++H01673///Palmoplantar keratoderma+++H00724///White sponge nevus+++H00691///Bullous congenital ichthyosiform erythroderma (BCIE)+++H00684///Pachyonychia congenita+++H00738///Ichthyosis with confetti+++H00796///Dermatopathia pigmentosa reticularis+++H00726///Meesmann corneal dystrophy+++H00667///Woolly hair+++H00722///Epidermolytic palmoplantar keratoderma (EPPK)+++H00708///Naegeli-Franceschetti-Jadassohn syndrome+++H00584///Epidermolysis bullosa simplex",null,null,"GO:0071944///cell periphery+++GO:0005886///plasma membrane+++GO:0042383///sarcolemma+++GO:0016010///dystrophin-associated glycoprotein complex+++GO:0070062///extracellular exosome+++GO:0016327///apicolateral plasma membrane+++GO:0043034///costamere+++GO:0005882///intermediate filament+++GO:0030018///Z disc+++GO:0005829///cytosol+++GO:1990357///terminal web","GO:0005200///structural constituent of cytoskeleton+++GO:0005198///structural molecule activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0008307///structural constituent of muscle","GO:0070268///cornification+++GO:0031424///keratinization+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:0043627///response to estrogen+++GO:0016032///viral process+++GO:0007219///Notch signaling pathway+++GO:0045214///sarcomere organization","IPR039008///Intermediate filament, rod domain+++IPR002957///Keratin, type I+++IPR001664///Intermediate filament protein+++IPR018039///Intermediate filament protein, conserved site","[K1C19_HUMAN|Reviewed]RecName: Full=Keratin, type I cytoskeletal 19; AltName: Full=Cytokeratin-19; Short=CK-19; AltName: Full=Keratin-19; Short=K19;+++[C9JM50_HUMAN|Unreviewed]SubName: Full=Keratin, type I cytoskeletal 19 {ECO:0000313|Ensembl:ENSP00000408759}; Flags: Fragment;+++[K7EMS3_HUMAN|Unreviewed]SubName: Full=Keratin, type I cytoskeletal 19 {ECO:0000313|Ensembl:ENSP00000466625}; Flags: Fragment;"]
[388341,"'LRRC75A'",22,25,23.5,"04621///NOD-like receptor signaling pathway+++04750///Inflammatory mediator regulation of TRP channels",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005216///ion channel activity+++GO:0015075///ion transmembrane transporter activity+++GO:0005261///cation channel activity+++GO:0005262///calcium channel activity","GO:0070588///calcium ion transmembrane transport+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0007600///sensory perception+++GO:0090280///positive regulation of calcium ion import+++GO:0009266///response to temperature stimulus+++GO:0009408///response to heat+++GO:0045773///positive regulation of axon extension","IPR032675///Leucine-rich repeat domain superfamily","[LR75A_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 75A; AltName: Full=Leucine-rich repeat-containing protein FAM211A;+++[B7ZMA3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAI44382.1}; Flags: Fragment;"]
[388559,"'ZNF888'",28.02,28,28.01,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box","[ZN888_HUMAN|Reviewed]RecName: Full=Zinc finger protein 888 {ECO:0000305};"]
[388695,"'LYSMD1'",90,99,94.5,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0006397///mRNA processing+++GO:0008380///RNA splicing","IPR018392///LysM domain+++IPR036779///LysM domain superfamily","[LYSM1_HUMAN|Reviewed]RecName: Full=LysM and putative peptidoglycan-binding domain-containing protein 1;"]
[388963,"'C2orf81'",137,77,107,{"$nulls":4},"GO:0005667///transcription factor complex+++GO:0035985///senescence-associated heterochromatin focus+++GO:0005829///cytosol+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0051575///5'-deoxyribose-5-phosphate lyase activity+++GO:0046965///retinoid X receptor binding+++GO:0001205///distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008134///transcription factor binding+++GO:0003680///AT DNA binding+++GO:0003906///DNA-(apurinic or apyrimidinic site) endonuclease activity+++GO:0003677///DNA binding+++GO:0019899///enzyme binding+++GO:0042975///peroxisome proliferator activated receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0042974///retinoic acid receptor binding+++GO:0003682///chromatin binding","GO:0006355///regulation of transcription, DNA-templated","IPR028042///Protein of unknown function DUF4639","[CB081_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C2orf81 {ECO:0000305};+++[A0A1W2PPJ4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf81 {ECO:0000313|Ensembl:ENSP00000491561}; Flags: Fragment;+++[A0A1W2PQG2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf81 {ECO:0000313|Ensembl:ENSP00000491941};+++[A0A1W2PRV2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf81 {ECO:0000313|Ensembl:ENSP00000492454}; Flags: Fragment;+++[A0A1W2PSA2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C2orf81 {ECO:0000313|Ensembl:ENSP00000492786}; Flags: Fragment;+++[G3XAA6_HUMAN|Unreviewed]SubName: Full=HCG40743, isoform CRA_a {ECO:0000313|EMBL:EAW99682.1};"]
[389199,"'LOC389199'",0,3,1.5,{"$nulls":8},"[Q8N5S0_HUMAN|Unreviewed]SubName: Full=Hypothetical gene supported by BC031673 {ECO:0000313|EMBL:AAH31673.1};"]
[389541,"'LAMTOR4'",276,175,225.5,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0071986///Ragulator complex+++GO:0043231///intracellular membrane-bounded organelle","GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032008///positive regulation of TOR signaling+++GO:0007050///cell cycle arrest+++GO:0008361///regulation of cell size+++GO:0061462///protein localization to lysosome+++GO:0016241///regulation of macroautophagy+++GO:0071230///cellular response to amino acid stimulus","IPR034601///Ragulator complex protein LAMTOR4","[LTOR4_HUMAN|Reviewed]RecName: Full=Ragulator complex protein LAMTOR4; AltName: Full=Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; Contains: RecName: Full=Ragulator complex protein LAMTOR4, N-terminally processed;+++[A0A087WT92_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR4 {ECO:0000313|Ensembl:ENSP00000477680};+++[A0A087WV46_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR4 {ECO:0000313|Ensembl:ENSP00000479176};+++[A0A087WVK8_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR4 {ECO:0000313|Ensembl:ENSP00000479500};+++[A0A087WVU0_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR4 {ECO:0000313|Ensembl:ENSP00000479685};+++[A0A087WWR0_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR4 {ECO:0000313|Ensembl:ENSP00000480432}; Flags: Fragment;+++[A0A087WXQ3_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR4 {ECO:0000313|Ensembl:ENSP00000481202}; Flags: Fragment;+++[C9JXA7_HUMAN|Unreviewed]SubName: Full=Ragulator complex protein LAMTOR4 {ECO:0000313|Ensembl:ENSP00000387926};"]
[389812,"'LCN15'",1,0,0.5,{"$nulls":4},"GO:0005576///extracellular region","GO:0036094///small molecule binding",null,"IPR012674///Calycin+++IPR000566///Lipocalin/cytosolic fatty-acid binding domain+++IPR002345///Lipocalin+++IPR022272///Lipocalin family conserved site","[LCN15_HUMAN|Reviewed]RecName: Full=Lipocalin-15; Flags: Precursor;+++[Q49AN5_HUMAN|Unreviewed]SubName: Full=LCN15 protein {ECO:0000313|EMBL:AAH35124.1};"]
[390205,"'LRRC10B'",4,2,3,{"$nulls":7},"IPR032675///Leucine-rich repeat domain superfamily+++IPR003591///Leucine-rich repeat, typical subtype+++IPR001611///Leucine-rich repeat","[LR10B_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 10B;"]
[391,"'RHOG'",1056,923,989.5,"05100///Bacterial invasion of epithelial cells+++05132///Salmonella infection+++05131///Shigellosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0042995///cell projection+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030667///secretory granule membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005938///cell cortex","GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0046934///phosphatidylinositol-4,5-bisphosphate 3-kinase activity+++GO:0005525///GTP binding+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding","GO:0043312///neutrophil degranulation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:1900027///regulation of ruffle assembly+++GO:0016601///Rac protein signal transduction+++GO:0030036///actin cytoskeleton organization+++GO:0007015///actin filament organization+++GO:0060326///cell chemotaxis+++GO:0008284///positive regulation of cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007163///establishment or maintenance of cell polarity+++GO:0007264///small GTPase mediated signal transduction+++GO:0046854///phosphatidylinositol phosphorylation+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0008360///regulation of cell shape+++GO:0007266///Rho protein signal transduction+++GO:0090630///activation of GTPase activity","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001806///Small GTPase+++IPR005225///Small GTP-binding protein domain+++IPR003578///Small GTPase Rho","[RHOG_HUMAN|Reviewed]RecName: Full=Rho-related GTP-binding protein RhoG; Flags: Precursor;+++[Q6ICQ8_HUMAN|Unreviewed]SubName: Full=ARHG protein {ECO:0000313|EMBL:CAG29331.1}; SubName: Full=Ras homolog gene family, member G (Rho G) {ECO:0000313|EMBL:AAI04178.1}; SubName: Full=Ras homolog gene family, member G (Rho G), isoform CRA_a {ECO:0000313|EMBL:EAX02575.1}; Flags: Fragment;"]
[392,"'ARHGAP1'",4308.43,4695,4501.715,{"$nulls":4},"GO:0097443///sorting endosome+++GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane","GO:0005070///SH3/SH2 adaptor activity+++GO:0045296///cadherin binding+++GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0017124///SH3 domain binding","GO:0016197///endosomal transport+++GO:0007165///signal transduction+++GO:0009967///positive regulation of signal transduction+++GO:2001136///negative regulation of endocytic recycling+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0033572///transferrin transport+++GO:0043547///positive regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction","IPR000198///Rho GTPase-activating protein domain+++IPR008936///Rho GTPase activation protein+++IPR001251///CRAL-TRIO lipid binding domain+++IPR036865///CRAL-TRIO lipid binding domain superfamily","[RHG01_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 1; AltName: Full=CDC42 GTPase-activating protein; AltName: Full=GTPase-activating protein rhoGAP; AltName: Full=Rho-related small GTPase protein activator; AltName: Full=Rho-type GTPase-activating protein 1; AltName: Full=p50-RhoGAP;+++[E9PNR6_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000432794}; Flags: Fragment;+++[H0YE29_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000434883}; Flags: Fragment;"]
[3936,"'LCP1'",130,128,129,{"$nulls":4},"GO:0001726///ruffle+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0005884///actin filament+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0030175///filopodium+++GO:0015629///actin cytoskeleton+++GO:0032432///actin filament bundle+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0005737///cytoplasm+++GO:0032587///ruffle membrane+++GO:0001891///phagocytic cup+++GO:0002102///podosome","GO:0003779///actin binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding+++GO:0042802///identical protein binding+++GO:0051020///GTPase binding+++GO:0051015///actin filament binding","GO:0071803///positive regulation of podosome assembly+++GO:0051017///actin filament bundle assembly+++GO:0002286///T cell activation involved in immune response+++GO:0031100///animal organ regeneration+++GO:0033157///regulation of intracellular protein transport+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0022617///extracellular matrix disassembly+++GO:0016477///cell migration+++GO:0051639///actin filament network formation+++GO:0010737///protein kinase A signaling+++GO:0051764///actin crosslink formation","IPR011992///EF-hand domain pair+++IPR039959///Fimbrin/Plastin+++IPR039953///Plastin-2+++IPR002048///EF-hand domain+++IPR018247///EF-Hand 1, calcium-binding site+++IPR036872///CH domain superfamily+++IPR001589///Actinin-type actin-binding domain, conserved site+++IPR001715///Calponin homology domain","[PLSL_HUMAN|Reviewed]RecName: Full=Plastin-2; AltName: Full=L-plastin; AltName: Full=LC64P; AltName: Full=Lymphocyte cytosolic protein 1; Short=LCP-1;+++[A0A024RDT4_HUMAN|Unreviewed]SubName: Full=Lymphocyte cytosolic protein 1 (L-plastin), isoform CRA_a {ECO:0000313|EMBL:EAX08758.1};+++[V9HWJ7_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 37 {ECO:0000313|EMBL:ACJ13702.1};"]
[3960,"'LGALS4'",2,2,2,"04146///Peroxisome",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0005829///cytosol","GO:0030246///carbohydrate binding+++GO:0016936///galactoside binding","GO:0007155///cell adhesion","IPR015533///Galectin-4/6+++IPR001079///Galectin, carbohydrate recognition domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily","[LEG4_HUMAN|Reviewed]RecName: Full=Galectin-4; Short=Gal-4; AltName: Full=Antigen NY-CO-27; AltName: Full=L-36 lactose-binding protein; Short=L36LBP; AltName: Full=Lactose-binding lectin 4;+++[M0QZ93_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079}; Flags: Fragment;+++[M0R1B2_HUMAN|Unreviewed]SubName: Full=Galectin-4 {ECO:0000313|Ensembl:ENSP00000471757}; Flags: Fragment;+++[M0R349_HUMAN|Unreviewed]SubName: Full=Galectin-4 {ECO:0000313|Ensembl:ENSP00000472990}; Flags: Fragment;+++[Q6FHZ4_HUMAN|Unreviewed]RecName: Full=Galectin {ECO:0000256|RuleBase:RU102079};"]
[3988,"'LIPA'",838,997,917.5,"04979///Cholesterol metabolism+++00100///Steroid biosynthesis+++04142///Lysosome","H00148///Lysosomal acid lipase deficiency",null,"R01462///cholesterol ester acylhydrolase   Cholesterol ester + H2O <=> Cholesterol + Fatty acid","GO:0043231///intracellular membrane-bounded organelle+++GO:0001650///fibrillar center+++GO:0005764///lysosome+++GO:0043202///lysosomal lumen","GO:0016298///lipase activity+++GO:0004771///sterol esterase activity","GO:0000902///cell morphogenesis+++GO:0034383///low-density lipoprotein particle clearance+++GO:0016042///lipid catabolic process+++GO:0008283///cell proliferation+++GO:0048771///tissue remodeling+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0030324///lung development+++GO:0001816///cytokine production+++GO:0006954///inflammatory response","IPR000073///Alpha/beta hydrolase fold-1+++IPR029058///Alpha/Beta hydrolase fold+++IPR006693///Partial AB-hydrolase lipase domain+++IPR025483///Lipase, eukaryotic","[LICH_HUMAN|Reviewed]RecName: Full=Lysosomal acid lipase/cholesteryl ester hydrolase; Short=Acid cholesteryl ester hydrolase; Short=LAL; EC=3.1.1.13; AltName: Full=Cholesteryl esterase; AltName: Full=Lipase A; AltName: Full=Sterol esterase; Flags: Precursor;+++[A0A0A0MT32_HUMAN|Unreviewed]SubName: Full=Lysosomal acid lipase/cholesteryl ester hydrolase {ECO:0000313|Ensembl:ENSP00000413019};"]
[399693,"'CCDC187'",0,1,0.5,{"$nulls":4},"GO:0005813///centrosome","GO:0008017///microtubule binding","GO:0034453///microtubule anchoring","IPR028750///Centrosome-associated protein 350","[CC187_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 187 {ECO:0000305};+++[A0A075B733_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 187 {ECO:0000313|Ensembl:ENSP00000456543};+++[A0A075B739_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 187 {ECO:0000313|Ensembl:ENSP00000457438};+++[A0A1W2PQX5_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 187 {ECO:0000313|Ensembl:ENSP00000492326};"]
[4000,"'LMNA'",6052,5445,5748.5,"05414///Dilated cardiomyopathy (DCM)+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++05410///Hypertrophic cardiomyopathy (HCM)+++04210///Apoptosis","H00590///Congenital muscular dystrophies (CMD/MDC)+++H00420///Familial partial lipodystrophy (FPL)+++H00294///Dilated cardiomyopathy (DCM)+++H00663///Restrictive dermopathy+++H00601///Hutchinson-Gilford progeria syndrome+++H00563///Emery-Dreifuss muscular dystrophy+++H00593///Limb-girdle muscular dystrophy (LGMD)+++H00264///Charcot-Marie-Tooth disease (CMT)+++H00665///Mandibuloacral dysplasia+++H01216///Left ventricular noncompaction (LVNC)",null,null,"GO:0005654///nucleoplasm+++GO:0005652///nuclear lamina+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0016607///nuclear speck+++GO:0005638///lamin filament+++GO:0005882///intermediate filament+++GO:0005635///nuclear envelope+++GO:0031965///nuclear membrane","GO:0005198///structural molecule activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0032204///regulation of telomere maintenance+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0006606///protein import into nucleus+++GO:0071456///cellular response to hypoxia+++GO:1903243///negative regulation of cardiac muscle hypertrophy in response to stress+++GO:0008285///negative regulation of cell proliferation+++GO:0034504///protein localization to nucleus+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0031647///regulation of protein stability+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0034613///cellular protein localization+++GO:0006997///nucleus organization+++GO:0055015///ventricular cardiac muscle cell development+++GO:0007084///mitotic nuclear envelope reassembly+++GO:1900114///positive regulation of histone H3-K9 trimethylation+++GO:0090343///positive regulation of cell aging+++GO:0006998///nuclear envelope organization+++GO:0010628///positive regulation of gene expression+++GO:1900180///regulation of protein localization to nucleus+++GO:0030334///regulation of cell migration+++GO:0007517///muscle organ development+++GO:0072201///negative regulation of mesenchymal cell proliferation","IPR001664///Intermediate filament protein+++IPR036415///Lamin tail domain superfamily+++IPR018039///Intermediate filament protein, conserved site+++IPR039008///Intermediate filament, rod domain+++IPR001322///Lamin tail domain","[LMNA_HUMAN|Reviewed]RecName: Full=Prelamin-A/C; Contains: RecName: Full=Lamin-A/C; AltName: Full=70 kDa lamin; AltName: Full=Renal carcinoma antigen NY-REN-32; Flags: Precursor;+++[A0A0C4DGC5_HUMAN|Unreviewed]SubName: Full=Prelamin-A/C {ECO:0000313|Ensembl:ENSP00000424977}; Flags: Fragment;+++[D6RB20_HUMAN|Unreviewed]SubName: Full=Prelamin-A/C {ECO:0000313|Ensembl:ENSP00000424518};+++[H0YAB0_HUMAN|Unreviewed]SubName: Full=Prelamin-A/C {ECO:0000313|Ensembl:ENSP00000426535}; Flags: Fragment;+++[Q3BDU5_HUMAN|Unreviewed]SubName: Full=Prelamin-A/C {ECO:0000313|Ensembl:ENSP00000355292}; SubName: Full=Rhabdomyosarcoma antigen MU-RMS-40.12 {ECO:0000313|EMBL:ABB04050.1};+++[Q5I6Y5_HUMAN|Unreviewed]SubName: Full=Lamin A/C transcript variant 1 {ECO:0000313|EMBL:AAW32539.1};+++[Q5TCI8_HUMAN|Unreviewed]SubName: Full=Prelamin-A/C {ECO:0000313|Ensembl:ENSP00000357280};+++[W8QEH3_HUMAN|Unreviewed]SubName: Full=Lamin A/C {ECO:0000313|EMBL:AHL67294.1};"]
[400073,"'C12orf76'",33,36,34.5,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04020///Calcium signaling pathway+++04621///NOD-like receptor signaling pathway+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0098794///postsynapse+++GO:0005887///integral component of plasma membrane","GO:0005524///ATP binding+++GO:0004931///extracellularly ATP-gated cation channel activity+++GO:0005216///ion channel activity+++GO:0001614///purinergic nucleotide receptor activity","GO:0098655///cation transmembrane transport+++GO:0033198///response to ATP+++GO:0035590///purinergic nucleotide receptor signaling pathway+++GO:0060079///excitatory postsynaptic potential+++GO:0006811///ion transport","IPR020683///Ankyrin repeat-containing domain+++IPR003903///Ubiquitin interacting motif+++IPR002110///Ankyrin repeat+++IPR021832///Ankyrin repeat domain-containing protein 13+++IPR019351///Protein of unknown function DUF2039+++IPR036770///Ankyrin repeat-containing domain superfamily","[CL076_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C12orf76;+++[A0A087WX00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf76 {ECO:0000313|Ensembl:ENSP00000480634};+++[A0A0B4J261_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf76 {ECO:0000313|Ensembl:ENSP00000450232};+++[F8VV97_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf76 {ECO:0000313|Ensembl:ENSP00000449939};+++[F8VYN6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf76 {ECO:0000313|Ensembl:ENSP00000448915};+++[F8VZK6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf76 {ECO:0000313|Ensembl:ENSP00000447351};+++[F8W0P4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein C12orf76 {ECO:0000313|Ensembl:ENSP00000447574};"]
[400668,"'PRSS57'",1,1,1,{"$nulls":4},"GO:0005576///extracellular region+++GO:0035578///azurophil granule lumen+++GO:0005615///extracellular space","GO:0004252///serine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0008201///heparin binding+++GO:0016787///hydrolase activity","GO:0006508///proteolysis","IPR018114///Serine proteases, trypsin family, histidine active site+++IPR001314///Peptidase S1A, chymotrypsin family+++IPR009003///Peptidase S1, PA clan+++IPR001254///Serine proteases, trypsin domain","[PRS57_HUMAN|Reviewed]RecName: Full=Serine protease 57; EC=3.4.21.- {ECO:0000269|PubMed:22474388, ECO:0000269|PubMed:23904161, ECO:0000269|PubMed:25156428}; AltName: Full=Neutrophil serine protease 4 {ECO:0000303|PubMed:22474388, ECO:0000303|PubMed:25156428}; Short=NSP4 {ECO:0000303|PubMed:22474388, ECO:0000303|PubMed:23904161, ECO:0000303|PubMed:25156428}; AltName: Full=Serine protease 1-like protein 1; Flags: Precursor;+++[A0A0A0MR61_HUMAN|Unreviewed]SubName: Full=Serine protease 57 {ECO:0000313|Ensembl:ENSP00000327386};+++[B7ZMF6_HUMAN|Unreviewed]SubName: Full=PRSSL1 protein {ECO:0000313|EMBL:AAI44506.1};"]
[400961,"'PAIP2B'",13,18,15.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0000900///translation repressor activity, mRNA regulatory element binding+++GO:0005515///protein binding","GO:0006417///regulation of translation+++GO:0045947///negative regulation of translational initiation","IPR009818///Ataxin-2, C-terminal","[PAI2B_HUMAN|Reviewed]RecName: Full=Polyadenylate-binding protein-interacting protein 2B; Short=PABP-interacting protein 2B; Short=PAIP-2B; Short=Poly(A)-binding protein-interacting protein 2B;"]
[401258,"'RAB44'",2,4,3,{"$nulls":4},"GO:0035579///specific granule membrane+++GO:0005886///plasma membrane+++GO:0035577///azurophil granule membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0005525///GTP binding","GO:0006886///intracellular protein transport+++GO:0043312///neutrophil degranulation+++GO:0032482///Rab protein signal transduction","IPR005225///Small GTP-binding protein domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR002048///EF-hand domain+++IPR011992///EF-hand domain pair+++IPR001806///Small GTPase","[RAB44_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-44;"]
[401535,"'C9orf170'",3,0,1.5,{"$nulls":8},"[CI170_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C9orf170;"]
[402160,"'CFAP99'",5,5,5,{"$nulls":4},"GO:0031514///motile cilium+++GO:0042995///cell projection+++GO:0005929///cilium",null,null,"IPR039341///Cilia- and flagella-associated protein 99","[CFA99_HUMAN|Reviewed]RecName: Full=Cilia- and flagella-associated protein 99 {ECO:0000312|HGNC:HGNC:51180};+++[A0A087WWY8_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 99 {ECO:0000313|Ensembl:ENSP00000480601};+++[A0A0U1RQC7_HUMAN|Unreviewed]SubName: Full=Cilia- and flagella-associated protein 99 {ECO:0000313|Ensembl:ENSP00000488922};"]
[4036,"'LRP2'",0,1,0.5,"04918///Thyroid hormone synthesis+++04340///Hedgehog signaling pathway+++04979///Cholesterol metabolism","H00886///Donnai-Barrow syndrome",null,null,"GO:0005794///Golgi apparatus+++GO:0005764///lysosome+++GO:0005903///brush border+++GO:0005768///endosome+++GO:0043235///receptor complex+++GO:0005905///clathrin-coated pit+++GO:0070062///extracellular exosome+++GO:0030139///endocytic vesicle+++GO:0031904///endosome lumen+++GO:0030665///clathrin-coated vesicle membrane+++GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0045177///apical part of cell+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0030424///axon+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0009897///external side of plasma membrane+++GO:0030425///dendrite+++GO:0016324///apical plasma membrane","GO:0051087///chaperone binding+++GO:0008144///drug binding+++GO:0035258///steroid hormone receptor binding+++GO:0005515///protein binding+++GO:0042954///lipoprotein transporter activity+++GO:0017124///SH3 domain binding+++GO:0046872///metal ion binding+++GO:0005041///low-density lipoprotein particle receptor activity+++GO:0005509///calcium ion binding","GO:0003148///outflow tract septum morphogenesis+++GO:0008584///male gonad development+++GO:0061024///membrane organization+++GO:0030514///negative regulation of BMP signaling pathway+++GO:0042953///lipoprotein transport+++GO:0006897///endocytosis+++GO:0070447///positive regulation of oligodendrocyte progenitor proliferation+++GO:0006629///lipid metabolic process+++GO:0061156///pulmonary artery morphogenesis+++GO:0030900///forebrain development+++GO:0030001///metal ion transport+++GO:0060976///coronary vasculature development+++GO:0008283///cell proliferation+++GO:0060982///coronary artery morphogenesis+++GO:1904447///folate import across plasma membrane+++GO:0060068///vagina development+++GO:0050769///positive regulation of neurogenesis+++GO:1905167///positive regulation of lysosomal protein catabolic process+++GO:0007605///sensory perception of sound+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0003281///ventricular septum development+++GO:0035904///aorta development+++GO:0001523///retinoid metabolic process+++GO:0042359///vitamin D metabolic process+++GO:0001843///neural tube closure+++GO:0007507///heart development+++GO:0003139///secondary heart field specification+++GO:0140058///neuron projection arborization+++GO:0006766///vitamin metabolic process+++GO:0006898///receptor-mediated endocytosis+++GO:0007399///nervous system development","IPR036055///LDL receptor-like superfamily+++IPR001881///EGF-like calcium-binding domain+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR013032///EGF-like, conserved site+++IPR019825///Legume lectin, beta chain, Mn/Ca-binding site+++IPR018097///EGF-like calcium-binding, conserved site+++IPR002172///Low-density lipoprotein (LDL) receptor class A repeat+++IPR000742///EGF-like domain+++IPR023415///Low-density lipoprotein (LDL) receptor class A, conserved site+++IPR011042///Six-bladed beta-propeller, TolB-like+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR000033///LDLR class B repeat+++IPR026823///Complement Clr-like EGF domain","[LRP2_HUMAN|Reviewed]RecName: Full=Low-density lipoprotein receptor-related protein 2; Short=LRP-2; AltName: Full=Glycoprotein 330; Short=gp330; AltName: Full=Megalin; Flags: Precursor;+++[E9PC35_HUMAN|Unreviewed]SubName: Full=Low-density lipoprotein receptor-related protein 2 {ECO:0000313|Ensembl:ENSP00000409813};+++[L8E983_HUMAN|Unreviewed]SubName: Full=Alternative protein LRP2 {ECO:0000313|EMBL:CCQ43266.1};+++[Q4ZG84_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LRP2 {ECO:0000313|EMBL:AAX88965.1}; Flags: Fragment;+++[Q53TL0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LRP2 {ECO:0000313|EMBL:AAY24266.1}; Flags: Fragment;+++[Q7Z5C0_HUMAN|Unreviewed]SubName: Full=Glycoprotein receptor gp330/megalin {ECO:0000313|EMBL:AAP88586.1};+++[Q7Z5C1_HUMAN|Unreviewed]SubName: Full=Glycoprotein receptor gp330/megalin {ECO:0000313|EMBL:AAP88585.1};+++[Q9NP34_HUMAN|Unreviewed]SubName: Full=Low density lipoprotein receptor-related protein II {ECO:0000313|EMBL:AAC17129.2}; Flags: Fragment;"]
[404734,"'ANKHD1-EIF4EBP3'",1101.9,1282.47,1192.185,{"$nulls":4},"GO:0005737///cytoplasm","GO:0003723///RNA binding","GO:0045087///innate immune response","IPR036612///K Homology domain, type 1 superfamily+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR004087///K Homology domain+++IPR020683///Ankyrin repeat-containing domain+++IPR002110///Ankyrin repeat+++IPR004088///K Homology domain, type 1","[ANKH1_HUMAN|Reviewed]RecName: Full=Ankyrin repeat and KH domain-containing protein 1; AltName: Full=HIV-1 Vpr-binding ankyrin repeat protein; AltName: Full=Multiple ankyrin repeats single KH domain; Short=hMASK;+++[H7C0V5_HUMAN|Unreviewed]SubName: Full=ANKHD1-EIF4EBP3 readthrough {ECO:0000313|Ensembl:ENSP00000396882}; Flags: Fragment;"]
[4060,"'LUM'",3705,5360,4532.5,"05205///Proteoglycans in cancer",{"$nulls":3},"GO:0043202///lysosomal lumen+++GO:0005615///extracellular space+++GO:0005796///Golgi lumen+++GO:0070062///extracellular exosome+++GO:0062023///collagen-containing extracellular matrix+++GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005583///fibrillar collagen trimer","GO:0005518///collagen binding+++GO:0005515///protein binding+++GO:0030021///extracellular matrix structural constituent conferring compression resistance+++GO:0005201///extracellular matrix structural constituent","GO:0042340///keratan sulfate catabolic process+++GO:0007601///visual perception+++GO:0030199///collagen fibril organization+++GO:0014070///response to organic cyclic compound+++GO:0018146///keratan sulfate biosynthetic process+++GO:0051216///cartilage development+++GO:0070848///response to growth factor+++GO:0032914///positive regulation of transforming growth factor beta1 production+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030198///extracellular matrix organization","IPR001611///Leucine-rich repeat+++IPR027219///Lumican+++IPR003591///Leucine-rich repeat, typical subtype+++IPR032675///Leucine-rich repeat domain superfamily+++IPR000372///Leucine-rich repeat N-terminal domain","[LUM_HUMAN|Reviewed]RecName: Full=Lumican; AltName: Full=Keratan sulfate proteoglycan lumican; Short=KSPG lumican; Flags: Precursor;"]
[407977,"'TNFSF12-TNFSF13'",0,4.4,2.2,"04672///Intestinal immune network for IgA production+++04060///Cytokine-cytokine receptor interaction+++05323///Rheumatoid arthritis",{"$nulls":3},"GO:0005615///extracellular space+++GO:0016020///membrane","GO:0005125///cytokine activity+++GO:0005164///tumor necrosis factor receptor binding","GO:0010469///regulation of signaling receptor activity+++GO:0006955///immune response","IPR008983///Tumour necrosis factor-like domain superfamily+++IPR021184///Tumour necrosis factor, conserved site+++IPR006052///Tumour necrosis factor domain","[TNF12_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 12; AltName: Full=APO3 ligand; AltName: Full=TNF-related weak inducer of apoptosis; Short=TWEAK; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 12, membrane form; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 12, secreted form;+++[A0A0A6YY99_HUMAN|Unreviewed]SubName: Full=Protein TNFSF12-TNFSF13 {ECO:0000313|Ensembl:ENSP00000293826};"]
[4093,"'SMAD9'",24,32.95,28.475,"04550///Signaling pathways regulating pluripotency of stem cells+++04350///TGF-beta signaling pathway","H01621///Pulmonary arterial hypertension (PAH)","M00679///BMP signaling",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005622///intracellular+++GO:0005654///nucleoplasm+++GO:0071141///SMAD protein complex","GO:0046872///metal ion binding+++GO:0030618///transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0071773///cellular response to BMP stimulus+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:0060395///SMAD protein signal transduction+++GO:0030509///BMP signaling pathway","IPR017855///SMAD-like domain superfamily+++IPR013019///MAD homology, MH1+++IPR001132///SMAD domain, Dwarfin-type+++IPR008984///SMAD/FHA domain superfamily+++IPR013790///Dwarfin+++IPR003619///MAD homology 1, Dwarfin-type+++IPR036578///SMAD MH1 domain superfamily","[SMAD9_HUMAN|Reviewed]RecName: Full=Mothers against decapentaplegic homolog 9; Short=MAD homolog 9; Short=Mothers against DPP homolog 9; AltName: Full=Madh6; AltName: Full=SMAD family member 9; Short=SMAD 9; Short=Smad9;+++[A0A024RDR3_HUMAN|Unreviewed]RecName: Full=Mothers against decapentaplegic homolog {ECO:0000256|RuleBase:RU361195}; Short=MAD homolog {ECO:0000256|RuleBase:RU361195}; Short=Mothers against DPP homolog {ECO:0000256|RuleBase:RU361195}; AltName: Full=SMAD family member {ECO:0000256|RuleBase:RU361195};"]
[4126,"'MANBA'",809,972,890.5,"00511///Other glycan degradation+++04142///Lysosome","H00422///Glycoproteinoses+++H00140///beta-Mannosidosis",null,null,"GO:0035577///azurophil granule membrane+++GO:0005764///lysosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0043202///lysosomal lumen","GO:0016787///hydrolase activity+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0005537///mannose binding+++GO:0004567///beta-mannosidase activity+++GO:0004553///hydrolase activity, hydrolyzing O-glycosyl compounds","GO:0043312///neutrophil degranulation+++GO:0009313///oligosaccharide catabolic process+++GO:0008152///metabolic process+++GO:0006464///cellular protein modification process+++GO:0006516///glycoprotein catabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0046355///mannan catabolic process","IPR008979///Galactose-binding-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR006103///Glycoside hydrolase family 2, catalytic domain+++IPR017853///Glycoside hydrolase superfamily+++IPR036156///Beta-Galactosidase/glucuronidase domain superfamily","[MANBA_HUMAN|Reviewed]RecName: Full=Beta-mannosidase; EC=3.2.1.25; AltName: Full=Lysosomal beta A mannosidase; AltName: Full=Mannanase; Short=Mannase; Flags: Precursor;+++[A0A2R8Y211_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000493465};+++[A0A2R8Y4U7_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000493992};+++[A0A2R8Y524_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000494462};+++[A0A2R8Y7A0_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000495846}; Flags: Fragment;+++[A0A2R8Y7A7_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000496137}; Flags: Fragment;+++[A0A2R8Y7N1_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000496399}; Flags: Fragment;+++[A0A2R8YCE9_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000493519};+++[A0A2R8YE79_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000495363};+++[A0A2R8YEC9_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000495483};+++[A0A2R8YG98_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000495818};+++[A7LFP5_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|EMBL:ABS29701.1}; EC=3.2.1.25 {ECO:0000313|EMBL:ABS29701.1};+++[D6RA01_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000422001};+++[E9PFW2_HUMAN|Unreviewed]SubName: Full=Beta-mannosidase {ECO:0000313|Ensembl:ENSP00000427322};+++[L8E9D5_HUMAN|Unreviewed]SubName: Full=Alternative protein MANBA {ECO:0000313|EMBL:CCQ43341.1};"]
[414157,"'C10orf62'",1,0,0.5,{"$nulls":5},"GO:0005515///protein binding",null,"IPR037649///Uncharacterized protein C10orf62","[CJ062_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C10orf62;"]
[415116,"'PIM3'",220,182,201,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0006915///apoptotic process+++GO:0006468///protein phosphorylation+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0016310///phosphorylation+++GO:0007346///regulation of mitotic cell cycle+++GO:0007049///cell cycle+++GO:0046777///protein autophosphorylation+++GO:0043066///negative regulation of apoptotic process","IPR008271///Serine/threonine-protein kinase, active site+++IPR017348///Serine/threonine-protein kinase pim-1/2/3+++IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site","[PIM3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase pim-3; EC=2.7.11.1;+++[Q6P2J9_HUMAN|Unreviewed]SubName: Full=PIM3 protein {ECO:0000313|EMBL:AAH64477.1}; Flags: Fragment;"]
[4173,"'MCM4'",281,368,324.5,"04113///Meiosis - yeast+++04111///Cell cycle - yeast+++04110///Cell cycle+++03030///DNA replication",null,"M00285///MCM complex",null,"GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0042555///MCM complex","GO:0003677///DNA binding+++GO:0005524///ATP binding+++GO:0017111///nucleoside-triphosphatase activity+++GO:0003697///single-stranded DNA binding+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0003678///DNA helicase activity+++GO:0005515///protein binding+++GO:0004003///ATP-dependent DNA helicase activity+++GO:0004386///helicase activity","GO:0032508///DNA duplex unwinding+++GO:0006260///DNA replication+++GO:0006268///DNA unwinding involved in DNA replication+++GO:0006270///DNA replication initiation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007049///cell cycle","IPR027925///MCM N-terminal domain+++IPR012340///Nucleic acid-binding, OB-fold+++IPR008047///Mini-chromosome maintenance complex protein 4+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR018525///Mini-chromosome maintenance, conserved site+++IPR031327///Mini-chromosome maintenance protein+++IPR001208///MCM domain+++IPR033762///MCM OB domain","[MCM4_HUMAN|Reviewed]RecName: Full=DNA replication licensing factor MCM4; EC=3.6.4.12; AltName: Full=CDC21 homolog; AltName: Full=P1-CDC21;+++[A0A024R7U6_HUMAN|Unreviewed]RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00536514}; EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00536514};+++[A4FS09_HUMAN|Unreviewed]SubName: Full=Minichromosome maintenance protein 4 {ECO:0000313|EMBL:CAM35476.1}; EC=3.6.1.15 {ECO:0000313|EMBL:CAM35476.1}; Flags: Fragment;+++[B3KMX0_HUMAN|Unreviewed]RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00536514}; EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00536514};+++[B4DLA6_HUMAN|Unreviewed]RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00536514}; EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00536514};+++[E5RFJ8_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000428833}; Flags: Fragment;+++[E5RFR3_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000430329}; Flags: Fragment;+++[E5RG31_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000427875}; Flags: Fragment;+++[E5RG53_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000427829};+++[E5RHP5_HUMAN|Unreviewed]SubName: Full=DNA replication licensing factor MCM4 {ECO:0000313|Ensembl:ENSP00000430864}; Flags: Fragment;"]
[4199,"'ME1'",308,289,298.5,"00710///Carbon fixation in photosynthetic organisms+++00620///Pyruvate metabolism+++01200///Carbon metabolism+++01120///Microbial metabolism in diverse environments+++01100///Metabolic pathways",null,"M00172///C4-dicarboxylic acid cycle, NADP - malic enzyme type+++M00169///CAM (Crassulacean acid metabolism), light","R00216///(S)-Malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating)   (S)-Malate + NADP+ <=> Pyruvate + CO2 + NADPH + H+","GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0051287///NAD binding+++GO:0004473///malate dehydrogenase (decarboxylating) (NADP+) activity+++GO:0050661///NADP binding+++GO:0004471///malate dehydrogenase (decarboxylating) (NAD+) activity+++GO:0008948///oxaloacetate decarboxylase activity+++GO:0030145///manganese ion binding+++GO:0043531///ADP binding+++GO:0004470///malic enzyme activity+++GO:0009055///electron transfer activity","GO:0006108///malate metabolic process+++GO:0051262///protein tetramerization+++GO:0019216///regulation of lipid metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0006741///NADP biosynthetic process+++GO:0009743///response to carbohydrate+++GO:0009725///response to hormone+++GO:1902031///regulation of NADP metabolic process+++GO:0006090///pyruvate metabolic process","IPR012301///Malic enzyme, N-terminal domain+++IPR037062///Malic enzyme, N-terminal domain superfamily+++IPR036291///NAD(P)-binding domain superfamily+++IPR001891///Malic oxidoreductase+++IPR012302///Malic enzyme, NAD-binding+++IPR015884///Malic enzyme, conserved site","[MAOX_HUMAN|Reviewed]RecName: Full=NADP-dependent malic enzyme; Short=NADP-ME; EC=1.1.1.40; AltName: Full=Malic enzyme 1;"]
[4217,"'MAP3K5'",25.76,22.19,23.975,"05418///Fluid shear stress and atherosclerosis+++04071///Sphingolipid signaling pathway+++04210///Apoptosis+++04010///MAPK signaling pathway+++04214///Apoptosis - fly+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04714///Thermogenesis+++05014///Amyotrophic lateral sclerosis (ALS)+++04722///Neurotrophin signaling pathway+++04668///TNF signaling pathway+++01524///Platinum drug resistance+++04013///MAPK signaling pathway - fly+++04530///Tight junction+++04141///Protein processing in endoplasmic reticulum",null,"M00689///MAPK (p38) signaling+++M00688///MAPK (JNK) signaling",null,"GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0032991///protein-containing complex+++GO:1902911///protein kinase complex+++GO:1990604///IRE1-TRAF2-ASK1 complex+++GO:0009897///external side of plasma membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0042803///protein homodimerization activity+++GO:0004709///MAP kinase kinase kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0019901///protein kinase binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0000287///magnesium ion binding+++GO:0019903///protein phosphatase binding+++GO:0005524///ATP binding+++GO:0042802///identical protein binding+++GO:0016301///kinase activity","GO:0016032///viral process+++GO:0002376///immune system process+++GO:0070301///cellular response to hydrogen peroxide+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0002931///response to ischemia+++GO:0038066///p38MAPK cascade+++GO:0034198///cellular response to amino acid starvation+++GO:0000165///MAPK cascade+++GO:0000187///activation of MAPK activity+++GO:0046330///positive regulation of JNK cascade+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0010941///regulation of cell death+++GO:0043507///positive regulation of JUN kinase activity+++GO:0016310///phosphorylation+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0000186///activation of MAPKK activity+++GO:0097190///apoptotic signaling pathway+++GO:0006468///protein phosphorylation+++GO:1901216///positive regulation of neuron death+++GO:0045663///positive regulation of myoblast differentiation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0071356///cellular response to tumor necrosis factor+++GO:0001934///positive regulation of protein phosphorylation+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0006915///apoptotic process+++GO:0007257///activation of JUN kinase activity+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0072577///endothelial cell apoptotic process+++GO:0043065///positive regulation of apoptotic process+++GO:1902170///cellular response to reactive nitrogen species+++GO:0042060///wound healing+++GO:0097300///programmed necrotic cell death+++GO:0051403///stress-activated MAPK cascade+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0007254///JNK cascade+++GO:0010666///positive regulation of cardiac muscle cell apoptotic process+++GO:0045087///innate immune response","IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR025136///Domain of unknown function DUF4071+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain","[M3K5_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase kinase kinase 5; EC=2.7.11.25; AltName: Full=Apoptosis signal-regulating kinase 1; Short=ASK-1; AltName: Full=MAPK/ERK kinase kinase 5; Short=MEK kinase 5; Short=MEKK 5;"]
[4248,"'MGAT3'",16,7,11.5,"00510///N-Glycan biosynthesis+++01100///Metabolic pathways",null,"M00075///N-glycan biosynthesis, complex type","R05986///UDP-N-acetyl-D-glucosamine + G00015 <=> UDP + G00019","GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane","GO:0003830///beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity","GO:0006487///protein N-linked glycosylation","IPR006813///Glycosyl transferase, family 17","[MGAT3_HUMAN|Reviewed]RecName: Full=Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase; EC=2.4.1.144; AltName: Full=N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase III; Short=GNT-III; Short=GlcNAc-T III; Short=N-acetylglucosaminyltransferase III;"]
[4285,"'MIPEP'",130,130,130,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0008237///metallopeptidase activity+++GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0004222///metalloendopeptidase activity","GO:0006627///protein processing involved in protein targeting to mitochondrion+++GO:0006518///peptide metabolic process+++GO:0006508///proteolysis","IPR024077///Neurolysin/Thimet oligopeptidase, domain 2+++IPR024079///Metallopeptidase, catalytic domain superfamily+++IPR033851///Mitochondrial intermediate peptidase+++IPR001567///Peptidase M3A/M3B catalytic domain","[MIPEP_HUMAN|Reviewed]RecName: Full=Mitochondrial intermediate peptidase; Short=MIP; EC=3.4.24.59; Flags: Precursor;"]
[4301,"'AFDN'",543,721,632,"04014///Ras signaling pathway+++04670///Leukocyte transendothelial migration+++04024///cAMP signaling pathway+++04015///Rap1 signaling pathway+++04520///Adherens junction+++04530///Tight junction",{"$nulls":3},"GO:0005911///cell-cell junction","GO:0017016///Ras GTPase binding+++GO:0008022///protein C-terminus binding+++GO:0045296///cadherin binding+++GO:0051015///actin filament binding","GO:0007165///signal transduction","IPR002710///Dilute domain+++IPR029071///Ubiquitin-like domain superfamily+++IPR008984///SMAD/FHA domain superfamily+++IPR000159///Ras-associating (RA) domain+++IPR028842///Afadin+++IPR036034///PDZ superfamily+++IPR000253///Forkhead-associated (FHA) domain+++IPR037977///Afadin, cargo binding domain+++IPR001478///PDZ domain","[AFAD_HUMAN|Reviewed]RecName: Full=Afadin; AltName: Full=ALL1-fused gene from chromosome 6 protein; Short=Protein AF-6; AltName: Full=Afadin adherens junction formation factor {ECO:0000312|HGNC:HGNC:7137};+++[A8MQ02_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000355771};+++[E9PFY5_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000383626}; Flags: Fragment;+++[F8W9I4_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000383625}; Flags: Fragment;+++[G1UI22_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|EMBL:BAK64145.1};+++[H0Y7R8_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000414675}; Flags: Fragment;+++[H0Y8L4_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000421441}; Flags: Fragment;+++[H0Y8U8_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000422166}; Flags: Fragment;+++[H0Y948_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000423035}; Flags: Fragment;+++[H0Y9I0_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000424188}; Flags: Fragment;+++[H0YA98_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000426462}; Flags: Fragment;+++[J3KN01_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000252692};+++[Q5TIG5_HUMAN|Unreviewed]SubName: Full=Afadin {ECO:0000313|Ensembl:ENSP00000341118};+++[Q96C95_HUMAN|Unreviewed]SubName: Full=MLLT4 protein {ECO:0000313|EMBL:AAH14505.1}; Flags: Fragment;"]
[431705,"'ASTL'",3,0,1.5,"04022///cGMP-PKG signaling pathway+++04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0030133///transport vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0060473///cortical granule+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm","GO:0004222///metalloendopeptidase activity+++GO:0046872///metal ion binding+++GO:0070001///aspartic-type peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0008270///zinc ion binding+++GO:0008233///peptidase activity+++GO:0070002///glutamic-type peptidase activity+++GO:0016787///hydrolase activity","GO:0006508///proteolysis+++GO:2000360///negative regulation of binding of sperm to zona pellucida+++GO:0060468///prevention of polyspermy+++GO:0010954///positive regulation of protein processing+++GO:0009566///fertilization+++GO:0007338///single fertilization+++GO:0007155///cell adhesion","IPR001506///Peptidase M12A+++IPR024079///Metallopeptidase, catalytic domain superfamily+++IPR006026///Peptidase, metallopeptidase","[ASTL_HUMAN|Reviewed]RecName: Full=Astacin-like metalloendopeptidase; EC=3.4.-.-; AltName: Full=Oocyte astacin; AltName: Full=Ovastacin; Flags: Precursor;+++[Q3B826_HUMAN|Unreviewed]RecName: Full=Metalloendopeptidase {ECO:0000256|RuleBase:RU361183}; EC=3.4.24.- {ECO:0000256|RuleBase:RU361183}; Flags: Fragment;"]
[435,"'ASL'",257,166,211.5,"01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00220///Arginine biosynthesis+++00250///Alanine, aspartate and glutamate metabolism+++01230///Biosynthesis of amino acids","H01398///Primary hyperammonemic disorders (Urea cycle disorders)+++H01028///Argininosuccinic aciduria (ARGINSA)","M00844///Arginine biosynthesis, ornithine => arginine+++M00845///Arginine biosynthesis, glutamate => acetylcitrulline => arginine+++M00029///Urea cycle","R01086///2-(Nomega-L-arginino)succinate arginine-lyase (fumarate-forming)   N-(L-Arginino)succinate <=> Fumarate + L-Arginine","GO:0005769///early endosome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0031901///early endosome membrane+++GO:0019005///SCF ubiquitin ligase complex+++GO:0055037///recycling endosome+++GO:0030173///integral component of Golgi membrane+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0000139///Golgi membrane","GO:0004842///ubiquitin-protein transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0004056///argininosuccinate lyase activity+++GO:0042803///protein homodimerization activity+++GO:0008476///protein-tyrosine sulfotransferase activity+++GO:0017137///Rab GTPase binding+++GO:0003677///DNA binding+++GO:0097602///cullin family protein binding+++GO:0008270///zinc ion binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding+++GO:0019904///protein domain specific binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity","GO:1900165///negative regulation of interleukin-6 secretion+++GO:0006612///protein targeting to membrane+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0050728///negative regulation of inflammatory response+++GO:0010265///SCF complex assembly+++GO:0043305///negative regulation of mast cell degranulation+++GO:0035518///histone H2A monoubiquitination+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0042450///arginine biosynthetic process via ornithine+++GO:0006478///peptidyl-tyrosine sulfation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006897///endocytosis+++GO:0002686///negative regulation of leukocyte migration+++GO:0048261///negative regulation of receptor-mediated endocytosis+++GO:0006954///inflammatory response+++GO:0000209///protein polyubiquitination+++GO:0051457///maintenance of protein location in nucleus+++GO:0051403///stress-activated MAPK cascade+++GO:0016567///protein ubiquitination+++GO:0038061///NIK/NF-kappaB signaling+++GO:0006879///cellular iron ion homeostasis+++GO:1900235///negative regulation of Kit signaling pathway+++GO:0000050///urea cycle+++GO:0015031///protein transport+++GO:0016055///Wnt signaling pathway+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0060368///regulation of Fc receptor mediated stimulatory signaling pathway+++GO:0043687///post-translational protein modification+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle","IPR029419///Argininosuccinate lyase, C-terminal+++IPR020557///Fumarate lyase, conserved site+++IPR024083///Fumarase/histidase, N-terminal+++IPR022761///Fumarate lyase, N-terminal+++IPR008948///L-Aspartase-like+++IPR000362///Fumarate lyase family+++IPR009049///Argininosuccinate lyase","[ARLY_HUMAN|Reviewed]RecName: Full=Argininosuccinate lyase; Short=ASAL; EC=4.3.2.1; AltName: Full=Arginosuccinase;+++[A0A024RDL8_HUMAN|Unreviewed]SubName: Full=Argininosuccinate lyase isoform 1 {ECO:0000313|EMBL:ALQ33378.1}; SubName: Full=Argininosuccinate lyase, isoform CRA_b {ECO:0000313|EMBL:EAX07946.1};+++[A0A0S2Z316_HUMAN|Unreviewed]SubName: Full=Argininosuccinate lyase isoform 2 {ECO:0000313|EMBL:ALQ33379.1}; Flags: Fragment;+++[A0A0S2Z3B0_HUMAN|Unreviewed]SubName: Full=Argininosuccinate lyase isoform 3 {ECO:0000313|EMBL:ALQ33380.1}; Flags: Fragment;+++[F8W943_HUMAN|Unreviewed]SubName: Full=Argininosuccinate lyase {ECO:0000313|Ensembl:ENSP00000354710}; Flags: Fragment;"]
[439,"'ASNA1'",2135,1635,1885,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0043529///GET complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0005730///nucleolus","GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016887///ATPase activity+++GO:0005215///transporter activity+++GO:0015105///arsenite transmembrane transporter activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity","GO:0045048///protein insertion into ER membrane+++GO:0071816///tail-anchored membrane protein insertion into ER membrane+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0015700///arsenite transport+++GO:0006620///posttranslational protein targeting to endoplasmic reticulum membrane","IPR025723///Anion-transporting ATPase-like domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR027542///Arsenical pump ATPase, ArsA/GET3, eukaryotic+++IPR016300///Arsenical pump ATPase, ArsA/GET3","[ASNA_HUMAN|Reviewed]RecName: Full=ATPase ASNA1 {ECO:0000255|HAMAP-Rule:MF_03112}; EC=3.6.-.- {ECO:0000255|HAMAP-Rule:MF_03112}; AltName: Full=Arsenical pump-driving ATPase {ECO:0000255|HAMAP-Rule:MF_03112}; AltName: Full=Arsenite-stimulated ATPase {ECO:0000255|HAMAP-Rule:MF_03112}; AltName: Full=Transmembrane domain recognition complex 40 kDa ATPase subunit; AltName: Full=hARSA-I; AltName: Full=hASNA-I;+++[A0A087WXS7_HUMAN|Unreviewed]RecName: Full=ATPase ASNA1 {ECO:0000256|HAMAP-Rule:MF_03112}; EC=3.6.-.- {ECO:0000256|HAMAP-Rule:MF_03112}; AltName: Full=Arsenical pump-driving ATPase {ECO:0000256|HAMAP-Rule:MF_03112}; AltName: Full=Arsenite-stimulated ATPase {ECO:0000256|HAMAP-Rule:MF_03112};+++[K7ERW9_HUMAN|Unreviewed]RecName: Full=Arsenical pump-driving ATPase {ECO:0000256|SAAS:SAAS00847228}; EC=3.6.-.- {ECO:0000256|SAAS:SAAS00846965}; Flags: Fragment;"]
[440345,"'NPIPB4'",2317.07,2276.92,2296.995,"04140///Autophagy - animal+++03015///mRNA surveillance pathway+++01100///Metabolic pathways+++00650///Butanoate metabolism+++04137///Mitophagy - animal",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004672///protein kinase activity+++GO:0042162///telomeric DNA binding+++GO:0046872///metal ion binding+++GO:0004674///protein serine/threonine kinase activity","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006406///mRNA export from nucleus+++GO:0032204///regulation of telomere maintenance+++GO:0006281///DNA repair+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0046777///protein autophosphorylation+++GO:0046854///phosphatidylinositol phosphorylation","IPR009443///Nuclear pore complex interacting protein+++IPR016024///Armadillo-type fold+++IPR035175///Serine/threonine-protein kinase SMG1, N-terminal","[NPIB4_HUMAN|Reviewed]RecName: Full=Nuclear pore complex-interacting protein family member B4;+++[A0A087WT63_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000477616};+++[C9JB18_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000339196}; Flags: Fragment;+++[E7EQW1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000429543}; Flags: Fragment;+++[F5H108_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000439732}; Flags: Fragment;+++[F5H3D4_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000439166};+++[F5H5F2_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000443445}; Flags: Fragment;+++[F5H8A1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex-interacting protein family member B4 {ECO:0000313|Ensembl:ENSP00000442065}; Flags: Fragment;+++[V9H0F5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAC31671.1}; Flags: Fragment;"]
[440730,"'TRIM67'",2,1,1.5,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:2000060///positive regulation of ubiquitin-dependent protein catabolic process+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:0010976///positive regulation of neuron projection development+++GO:1903827///regulation of cellular protein localization","IPR003961///Fibronectin type III+++IPR036116///Fibronectin type III superfamily+++IPR003877///SPRY domain+++IPR017907///Zinc finger, RING-type, conserved site+++IPR018957///Zinc finger, C3HC4 RING-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR003649///B-box, C-terminal+++IPR017903///COS domain+++IPR000315///B-box-type zinc finger+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR001870///B30.2/SPRY domain+++IPR001841///Zinc finger, RING-type+++IPR013783///Immunoglobulin-like fold","[TRI67_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 67; AltName: Full=TRIM9-like protein;+++[F8W8C1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 67 {ECO:0000313|Ensembl:ENSP00000412124};+++[L8E9I3_HUMAN|Unreviewed]SubName: Full=Alternative protein TRIM67 {ECO:0000313|EMBL:CCQ43013.1};"]
[441155,"'LOC441155'",1.61,4.19,2.9,{"$nulls":5},"GO:0046872///metal ion binding",null,"IPR000571///Zinc finger, CCCH-type","[B4DYM8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60373, highly similar to Zinc finger CCCH domain-containing protein11A {ECO:0000313|EMBL:BAG63790.1};"]
[441495,"'CENPVL2'",17.04,7.64,12.34,{"$nulls":5},"GO:0016846///carbon-sulfur lyase activity","GO:0008152///metabolic process","IPR006913///Glutathione-dependent formaldehyde-activating enzyme/centromere protein V+++IPR011057///Mss4-like superfamily","[CENL2_HUMAN|Reviewed]RecName: Full=Centromere protein V-like protein 2 {ECO:0000305}; AltName: Full=Centromere protein V pseudogene 2 {ECO:0000312|HGNC:HGNC:43879};"]
[4437,"'MSH3'",237.21,254.02,245.615,"01524///Platinum drug resistance+++03430///Mismatch repair+++05210///Colorectal cancer+++05200///Pathways in cancer","H00020///Colorectal cancer",null,null,"GO:0005654///nucleoplasm+++GO:0032300///mismatch repair complex+++GO:0005634///nucleus+++GO:0032302///MutSbeta complex+++GO:0016020///membrane","GO:0008094///DNA-dependent ATPase activity+++GO:0000166///nucleotide binding+++GO:0030983///mismatched DNA binding+++GO:0005515///protein binding+++GO:0003697///single-stranded DNA binding+++GO:0032181///dinucleotide repeat insertion binding+++GO:0032139///dinucleotide insertion or deletion binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0032142///single guanine insertion binding+++GO:0019899///enzyme binding+++GO:0000406///double-strand/single-strand DNA junction binding+++GO:0032137///guanine/thymine mispair binding+++GO:0032143///single thymine insertion binding+++GO:0005524///ATP binding+++GO:0032357///oxidized purine DNA binding+++GO:0003684///damaged DNA binding","GO:0051096///positive regulation of helicase activity+++GO:0043570///maintenance of DNA repeat elements+++GO:0006312///mitotic recombination+++GO:0006298///mismatch repair+++GO:0007131///reciprocal meiotic recombination+++GO:0043111///replication fork arrest+++GO:0045910///negative regulation of DNA recombination+++GO:0000710///meiotic mismatch repair+++GO:0006974///cellular response to DNA damage stimulus+++GO:0000735///removal of nonhomologous ends+++GO:0006281///DNA repair","IPR036187///DNA mismatch repair protein MutS, core domain superfamily+++IPR036678///MutS, connector domain superfamily+++IPR007695///DNA mismatch repair protein MutS-like, N-terminal+++IPR007860///DNA mismatch repair protein MutS, connector domain+++IPR007696///DNA mismatch repair protein MutS, core+++IPR000432///DNA mismatch repair protein MutS, C-terminal+++IPR016151///DNA mismatch repair protein MutS, N-terminal+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR017261///DNA mismatch repair protein MutS/MSH","[MSH3_HUMAN|Reviewed]RecName: Full=DNA mismatch repair protein Msh3; Short=hMSH3; AltName: Full=Divergent upstream protein; Short=DUP; AltName: Full=Mismatch repair protein 1; Short=MRP1;"]
[4486,"'MST1R'",10,18,14,{"$nulls":4},"GO:0001725///stress fiber+++GO:0043235///receptor complex+++GO:0005886///plasma membrane+++GO:0005773///vacuole+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0004713///protein tyrosine kinase activity+++GO:0017147///Wnt-protein binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004672///protein kinase activity+++GO:0019899///enzyme binding+++GO:0005011///macrophage colony-stimulating factor receptor activity+++GO:0016301///kinase activity+++GO:0004888///transmembrane signaling receptor activity","GO:0002376///immune system process+++GO:0043406///positive regulation of MAP kinase activity+++GO:0006952///defense response+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0009615///response to virus+++GO:0045087///innate immune response+++GO:0007338///single fertilization+++GO:0048012///hepatocyte growth factor receptor signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0006468///protein phosphorylation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0016310///phosphorylation+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0008284///positive regulation of cell proliferation+++GO:0038145///macrophage colony-stimulating factor signaling pathway+++GO:0009968///negative regulation of signal transduction","IPR002909///IPT domain+++IPR014756///Immunoglobulin E-set+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR016244///Tyrosine-protein kinase, HGF/MSP receptor+++IPR016201///PSI domain+++IPR001627///Sema domain+++IPR017441///Protein kinase, ATP binding site+++IPR039413///RON, Sema domain+++IPR008266///Tyrosine-protein kinase, active site+++IPR013783///Immunoglobulin-like fold+++IPR020635///Tyrosine-protein kinase, catalytic domain+++IPR036352///Sema domain superfamily+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain","[RON_HUMAN|Reviewed]RecName: Full=Macrophage-stimulating protein receptor; Short=MSP receptor; EC=2.7.10.1; AltName: Full=CDw136; AltName: Full=Protein-tyrosine kinase 8; AltName: Full=p185-Ron; AltName: CD_antigen=CD136; Contains: RecName: Full=Macrophage-stimulating protein receptor alpha chain; Contains: RecName: Full=Macrophage-stimulating protein receptor beta chain; Flags: Precursor;+++[A0A087WZQ8_HUMAN|Unreviewed]SubName: Full=Macrophage-stimulating protein receptor {ECO:0000313|Ensembl:ENSP00000482827};+++[B4E058_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50323, highly similar to Macrophage-stimulating protein receptor {ECO:0000313|EMBL:BAG64320.1};+++[G9JXB8_HUMAN|Unreviewed]SubName: Full=RON variant E2E3 {ECO:0000313|EMBL:AEW68340.1};+++[H2E272_HUMAN|Unreviewed]SubName: Full=MST1R variant RON30 {ECO:0000313|EMBL:AEY68264.1}; SubName: Full=Macrophage-stimulating protein receptor {ECO:0000313|Ensembl:ENSP00000481084};+++[H7C074_HUMAN|Unreviewed]SubName: Full=Macrophage-stimulating protein receptor {ECO:0000313|Ensembl:ENSP00000393294}; Flags: Fragment;+++[H7C3Z8_HUMAN|Unreviewed]SubName: Full=Macrophage-stimulating protein receptor {ECO:0000313|Ensembl:ENSP00000414792}; Flags: Fragment;+++[J3KQS7_HUMAN|Unreviewed]SubName: Full=Macrophage-stimulating protein receptor {ECO:0000313|Ensembl:ENSP00000407926};+++[K9JYP4_HUMAN|Unreviewed]SubName: Full=RON variant 21 {ECO:0000313|EMBL:AEB22138.1}; Flags: Fragment;"]
[4534,"'MTM1'",66,87,76.5,"04070///Phosphatidylinositol signaling system+++00562///Inositol phosphate metabolism+++01100///Metabolic pathways","H00700///Centronuclear myopathy",null,"R03330///D-myo-Inositol-1,3-bisphosphate 3-phosphohydrolase   D-myo-Inositol 1,3-bisphosphate + H2O <=> Inositol 1-phosphate + Orthophosphate+++R03363///1-Phosphatidyl-1D-myo-inositol 3-phosphate 3-phosphohydrolase   1-Phosphatidyl-1D-myo-inositol 3-phosphate + H2O <=> 1-Phosphatidyl-D-myo-inositol + Orthophosphate+++R06875///1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate 3-phosphohydrolase   1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate + H2O <=> 1-Phosphatidyl-1D-myo-inositol 4-phosphate + Orthophosphate","GO:0005770///late endosome+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030175///filopodium+++GO:0001726///ruffle+++GO:0005623///cell+++GO:0031674///I band+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0005768///endosome","GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0035091///phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0019215///intermediate filament binding+++GO:0016787///hydrolase activity+++GO:0052629///phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016791///phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity","GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006629///lipid metabolic process+++GO:0008333///endosome to lysosome transport+++GO:0070584///mitochondrion morphogenesis+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:1902902///negative regulation of autophagosome assembly+++GO:0046716///muscle cell cellular homeostasis+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:0048311///mitochondrion distribution+++GO:0044088///regulation of vacuole organization+++GO:0015031///protein transport+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0045109///intermediate filament organization+++GO:0016311///dephosphorylation+++GO:0032007///negative regulation of TOR signaling+++GO:0006470///protein dephosphorylation+++GO:0046856///phosphatidylinositol dephosphorylation","IPR016130///Protein-tyrosine phosphatase, active site+++IPR011993///PH-like domain superfamily+++IPR000387///Tyrosine specific protein phosphatases domain+++IPR010569///Myotubularin-like phosphatase domain+++IPR003595///Protein-tyrosine phosphatase, catalytic+++IPR029021///Protein-tyrosine phosphatase-like+++IPR004182///GRAM domain+++IPR030564///Myotubularin family+++IPR030561///Myotubularin","[MTM1_HUMAN|Reviewed]RecName: Full=Myotubularin; AltName: Full=Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; EC=3.1.3.95 {ECO:0000269|PubMed:12646134}; AltName: Full=Phosphatidylinositol-3-phosphate phosphatase; EC=3.1.3.64 {ECO:0000269|PubMed:10900271, ECO:0000269|PubMed:11001925, ECO:0000269|PubMed:12646134, ECO:0000269|PubMed:12847286};+++[A0A024RC06_HUMAN|Unreviewed]SubName: Full=Myotubularin 1, isoform CRA_a {ECO:0000313|EMBL:EAW99378.1};+++[C9J2A2_HUMAN|Unreviewed]SubName: Full=Myotubularin {ECO:0000313|Ensembl:ENSP00000400699}; Flags: Fragment;"]
[4599,"'MX1'",10775.29,9805.5,10290.395,"05162///Measles+++05165///Human papillomavirus infection+++05164///Influenza A",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0031966///mitochondrial membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane","GO:0005525///GTP binding+++GO:0042802///identical protein binding+++GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0008017///microtubule binding","GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0061025///membrane fusion+++GO:0000266///mitochondrial fission+++GO:0009615///response to virus+++GO:0045071///negative regulation of viral genome replication+++GO:0051607///defense response to virus+++GO:0006952///defense response+++GO:0034340///response to type I interferon+++GO:0060337///type I interferon signaling pathway+++GO:0002376///immune system process+++GO:0045087///innate immune response+++GO:0006915///apoptotic process+++GO:0007165///signal transduction","IPR019762///Dynamin, GTPase region, conserved site+++IPR022812///Dynamin superfamily+++IPR000375///Dynamin central domain+++IPR020850///GTPase effector domain+++IPR003130///Dynamin GTPase effector+++IPR030381///Dynamin-type guanine nucleotide-binding (G) domain+++IPR001401///Dynamin, GTPase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[MX1_HUMAN|Reviewed]RecName: Full=Interferon-induced GTP-binding protein Mx1; AltName: Full=Interferon-induced protein p78; Short=IFI-78K; AltName: Full=Interferon-regulated resistance GTP-binding protein MxA; AltName: Full=Myxoma resistance protein 1; AltName: Full=Myxovirus resistance protein 1; Contains: RecName: Full=Interferon-induced GTP-binding protein Mx1, N-terminally processed;+++[F8W8T1_HUMAN|Unreviewed]SubName: Full=Interferon-induced GTP-binding protein Mx1 {ECO:0000313|Ensembl:ENSP00000288383};+++[H9KVC3_HUMAN|Unreviewed]SubName: Full=Interferon-induced GTP-binding protein Mx1 {ECO:0000313|Ensembl:ENSP00000392151}; Flags: Fragment;+++[H9KVC4_HUMAN|Unreviewed]SubName: Full=Interferon-induced GTP-binding protein Mx1 {ECO:0000313|Ensembl:ENSP00000393931}; Flags: Fragment;+++[H9KVC7_HUMAN|Unreviewed]SubName: Full=Interferon-induced GTP-binding protein Mx1 {ECO:0000313|Ensembl:ENSP00000400923}; Flags: Fragment;+++[H9KVC9_HUMAN|Unreviewed]SubName: Full=Interferon-induced GTP-binding protein Mx1 {ECO:0000313|Ensembl:ENSP00000402215}; Flags: Fragment;+++[H9KVD0_HUMAN|Unreviewed]SubName: Full=Interferon-induced GTP-binding protein Mx1 {ECO:0000313|Ensembl:ENSP00000408498}; Flags: Fragment;+++[H9KVD3_HUMAN|Unreviewed]SubName: Full=Interferon-induced GTP-binding protein Mx1 {ECO:0000313|Ensembl:ENSP00000410989}; Flags: Fragment;"]
[4621,"'MYH3'",9,28,18.5,"04530///Tight junction","H02051///May-Hegglin anomaly+++H02052///Sebastian syndrome+++H01229///Inclusion body myopathy 3 (IBM3)+++H00801///Familial thoracic aortic aneurysm and dissection (TAAD)+++H00604///Deafness, autosomal dominant+++H01740///Macrothrombocytopenia+++H00811///Distal arthrogryposis (DA)+++H00578///Epstein syndrome+++H02053///Fechtner syndrome+++H01630///Patent ductus arteriosus+++H00233///MYH9-related disease+++H00872///Trismus-pseudocamptodactyly syndrome",null,null,"GO:0043292///contractile fiber+++GO:0016459///myosin complex+++GO:0030017///sarcomere+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005859///muscle myosin complex+++GO:0032982///myosin filament+++GO:0005829///cytosol+++GO:0030016///myofibril","GO:0005524///ATP binding+++GO:0051015///actin filament binding+++GO:0042623///ATPase activity, coupled+++GO:0003774///motor activity+++GO:0003779///actin binding+++GO:0000146///microfilament motor activity+++GO:0000166///nucleotide binding+++GO:0005516///calmodulin binding+++GO:0017018///myosin phosphatase activity","GO:0030326///embryonic limb morphogenesis+++GO:0030049///muscle filament sliding+++GO:0006470///protein dephosphorylation+++GO:0045214///sarcomere organization+++GO:0060325///face morphogenesis+++GO:0046034///ATP metabolic process+++GO:0007517///muscle organ development+++GO:0003009///skeletal muscle contraction+++GO:0030048///actin filament-based movement","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR036961///Kinesin motor domain superfamily+++IPR004009///Myosin, N-terminal, SH3-like+++IPR027401///Myosin IQ motif-containing domain superfamily+++IPR008989///Myosin S1 fragment, N-terminal+++IPR000048///IQ motif, EF-hand binding site+++IPR036000///Class II myosin, Myh3, motor domain+++IPR002928///Myosin tail+++IPR001609///Myosin head, motor domain","[MYH3_HUMAN|Reviewed]RecName: Full=Myosin-3; AltName: Full=Muscle embryonic myosin heavy chain; AltName: Full=Myosin heavy chain 3; AltName: Full=Myosin heavy chain, fast skeletal muscle, embryonic; AltName: Full=SMHCE;+++[Q5GJ67_HUMAN|Unreviewed]SubName: Full=Hypothetical rhabdomyosarcoma antigen MU-RMS-40.3 {ECO:0000313|EMBL:AAT44528.1}; Flags: Fragment;"]
[4643,"'MYO1E'",3235,4004,3619.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00604///Deafness, autosomal dominant+++H00626///Focal segmental glomerulosclerosis",null,null,"GO:0005730///nucleolus+++GO:0045334///clathrin-coated endocytic vesicle+++GO:0042995///cell projection+++GO:0005634///nucleus+++GO:0005643///nuclear pore+++GO:0005737///cytoplasm+++GO:0030659///cytoplasmic vesicle membrane+++GO:0030054///cell junction+++GO:0045335///phagocytic vesicle+++GO:0031941///filamentous actin+++GO:0005902///microvillus+++GO:0030136///clathrin-coated vesicle+++GO:0031410///cytoplasmic vesicle+++GO:0005903///brush border+++GO:0032420///stereocilium+++GO:0032587///ruffle membrane+++GO:0016020///membrane+++GO:0001726///ruffle+++GO:0009925///basal plasma membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005911///cell-cell junction+++GO:0016461///unconventional myosin complex+++GO:0016328///lateral plasma membrane+++GO:0005912///adherens junction+++GO:0016459///myosin complex+++GO:0016604///nuclear body+++GO:0060171///stereocilium membrane+++GO:0001725///stress fiber+++GO:0005886///plasma membrane+++GO:0015629///actin cytoskeleton+++GO:0005856///cytoskeleton+++GO:0045121///membrane raft+++GO:0032421///stereocilium bundle+++GO:0070062///extracellular exosome","GO:0000166///nucleotide binding+++GO:0042623///ATPase activity, coupled+++GO:0008289///lipid binding+++GO:0000146///microfilament motor activity+++GO:0003774///motor activity+++GO:0017160///Ral GTPase binding+++GO:0005516///calmodulin binding+++GO:0008022///protein C-terminus binding+++GO:0003779///actin binding+++GO:0005102///signaling receptor binding+++GO:0003712///transcription coregulator activity+++GO:0035091///phosphatidylinositol binding+++GO:0030898///actin-dependent ATPase activity+++GO:0042802///identical protein binding+++GO:0005524///ATP binding+++GO:0051015///actin filament binding+++GO:0005515///protein binding","GO:0035166///post-embryonic hemopoiesis+++GO:0072015///glomerular visceral epithelial cell development+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0032836///glomerular basement membrane development+++GO:0006605///protein targeting+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0051028///mRNA transport+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0032480///negative regulation of type I interferon production+++GO:0006612///protein targeting to membrane+++GO:0006366///transcription by RNA polymerase II+++GO:0045824///negative regulation of innate immune response+++GO:0030050///vesicle transport along actin filament+++GO:1903506///regulation of nucleic acid-templated transcription+++GO:0001570///vasculogenesis+++GO:0015031///protein transport+++GO:2000810///regulation of bicellular tight junction assembly+++GO:0006954///inflammatory response+++GO:0001822///kidney development+++GO:0006897///endocytosis+++GO:0030048///actin filament-based movement+++GO:0071346///cellular response to interferon-gamma+++GO:0038089///positive regulation of cell migration by vascular endothelial growth factor signaling pathway+++GO:1900748///positive regulation of vascular endothelial growth factor signaling pathway+++GO:0030838///positive regulation of actin filament polymerization+++GO:0007259///JAK-STAT cascade+++GO:0006807///nitrogen compound metabolic process+++GO:0001701///in utero embryonic development+++GO:1902524///positive regulation of protein K48-linked ubiquitination+++GO:0003094///glomerular filtration+++GO:0030097///hemopoiesis+++GO:0045358///negative regulation of interferon-beta biosynthetic process+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0045355///negative regulation of interferon-alpha biosynthetic process+++GO:1900078///positive regulation of cellular response to insulin stimulus","IPR036072///Class I myosin, motor domain+++IPR001609///Myosin head, motor domain+++IPR035507///Unconventional myosin-Ie/If, SH3 domain+++IPR000048///IQ motif, EF-hand binding site+++IPR010926///Class I myosin tail homology domain+++IPR036028///SH3-like domain superfamily+++IPR036961///Kinesin motor domain superfamily+++IPR001452///SH3 domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[MYO1E_HUMAN|Reviewed]RecName: Full=Unconventional myosin-Ie; AltName: Full=Myosin-Ic; AltName: Full=Unconventional myosin 1E;+++[A1L180_HUMAN|Unreviewed]SubName: Full=MYO1C protein {ECO:0000313|EMBL:AAI27785.1}; Flags: Fragment;+++[D3DTH7_HUMAN|Unreviewed]SubName: Full=Myosin IC, isoform CRA_a {ECO:0000313|EMBL:EAW90620.1};+++[F5H6E2_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ic {ECO:0000313|Ensembl:ENSP00000437685};+++[H0YLE5_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ie {ECO:0000313|Ensembl:ENSP00000453178}; Flags: Fragment;+++[H0YLJ4_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ie {ECO:0000313|Ensembl:ENSP00000453232}; Flags: Fragment;+++[H0YN00_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ie {ECO:0000313|Ensembl:ENSP00000453811};+++[H0YNB0_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ie {ECO:0000313|Ensembl:ENSP00000453936}; Flags: Fragment;+++[H0YNQ8_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ie {ECO:0000313|Ensembl:ENSP00000454113}; Flags: Fragment;+++[I3L204_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ic {ECO:0000313|Ensembl:ENSP00000459271}; Flags: Fragment;+++[I3L2C3_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ic {ECO:0000313|Ensembl:ENSP00000459558}; Flags: Fragment;+++[I3L3F5_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ic {ECO:0000313|Ensembl:ENSP00000460415}; Flags: Fragment;+++[I3L3Y6_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ic {ECO:0000313|Ensembl:ENSP00000460831}; Flags: Fragment;+++[I3L501_HUMAN|Unreviewed]SubName: Full=Unconventional myosin-Ic {ECO:0000313|Ensembl:ENSP00000461682}; Flags: Fragment;+++[Q4KMR3_HUMAN|Unreviewed]SubName: Full=MYO1E variant protein {ECO:0000313|EMBL:BAG06731.1}; SubName: Full=Myosin IE {ECO:0000313|EMBL:AAH98392.1}; SubName: Full=cDNA FLJ76307, highly similar to Homo sapiens myosin IE (MYO1E), mRNA {ECO:0000313|EMBL:BAF84377.1};"]
[4666,"'NACA'",3817,2987,3402,"04928///Parathyroid hormone synthesis, secretion and action",{"$nulls":3},"GO:0005854///nascent polypeptide-associated complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0003713///transcription coactivator activity+++GO:0003677///DNA binding","GO:0010664///negative regulation of striated muscle cell apoptotic process+++GO:0003231///cardiac ventricle development+++GO:0061384///heart trabecula morphogenesis+++GO:0048633///positive regulation of skeletal muscle tissue growth+++GO:1901227///negative regulation of transcription from RNA polymerase II promoter involved in heart development+++GO:1901228///positive regulation of transcription from RNA polymerase II promoter involved in heart development+++GO:0043403///skeletal muscle tissue regeneration+++GO:0006412///translation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:2000138///positive regulation of cell proliferation involved in heart morphogenesis+++GO:0015031///protein transport","IPR002715///Nascent polypeptide-associated complex NAC domain+++IPR038187///NAC A/B domain superfamily+++IPR016641///Nascent polypeptide-associated complex subunit alpha","[NACA_HUMAN|Reviewed]RecName: Full=Nascent polypeptide-associated complex subunit alpha; Short=NAC-alpha; AltName: Full=Alpha-NAC; AltName: Allergen=Hom s 2;+++[NACAM_HUMAN|Reviewed]RecName: Full=Nascent polypeptide-associated complex subunit alpha, muscle-specific form; AltName: Full=Alpha-NAC, muscle-specific form; Short=skNAC;+++[A0A024RB41_HUMAN|Unreviewed]SubName: Full=HCG2016482, isoform CRA_b {ECO:0000313|EMBL:EAW96961.1};+++[F8VNW4_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000450383}; Flags: Fragment;+++[F8VZ58_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000447764}; Flags: Fragment;+++[F8VZJ2_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000447705};+++[F8W029_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000446745};+++[F8W0C7_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000447207};+++[F8W0W4_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000447133}; Flags: Fragment;+++[F8W1N5_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000446933}; Flags: Fragment;+++[H0YHX9_HUMAN|Unreviewed]SubName: Full=Nascent polypeptide-associated complex subunit alpha {ECO:0000313|Ensembl:ENSP00000448039}; Flags: Fragment;"]
[4684,"'NCAM1'",523,647,585,"04514///Cell adhesion molecules (CAMs)+++05020///Prion diseases",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0031225///anchored component of membrane+++GO:0016021///integral component of membrane+++GO:0009986///cell surface+++GO:0000139///Golgi membrane+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0001618///virus receptor activity","GO:0000165///MAPK cascade+++GO:2001260///regulation of semaphorin-plexin signaling pathway+++GO:0016032///viral process+++GO:0071679///commissural neuron axon guidance+++GO:0046718///viral entry into host cell+++GO:0007411///axon guidance+++GO:0060333///interferon-gamma-mediated signaling pathway+++GO:0007155///cell adhesion","IPR003599///Immunoglobulin subtype+++IPR013783///Immunoglobulin-like fold+++IPR013098///Immunoglobulin I-set+++IPR036179///Immunoglobulin-like domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR036116///Fibronectin type III superfamily+++IPR003961///Fibronectin type III+++IPR033019///Neural cell adhesion molecule 1+++IPR003598///Immunoglobulin subtype 2+++IPR009138///Neural cell adhesion","[NCAM1_HUMAN|Reviewed]RecName: Full=Neural cell adhesion molecule 1; Short=N-CAM-1; Short=NCAM-1; AltName: CD_antigen=CD56; Flags: Precursor;+++[A0A087WTE4_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000477808};+++[A0A087WTF6_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000477835};+++[A0A087WTR3_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000478072}; Flags: Fragment;+++[A0A087WV75_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000479241};+++[A0A087WVD0_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000479353}; Flags: Fragment;+++[A0A087WVU1_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000479687}; Flags: Fragment;+++[A0A087WWD4_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000480132};+++[A0A087WWJ5_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000480269}; Flags: Fragment;+++[A0A087WX77_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000480797};+++[A0A087WZS4_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000482852}; Flags: Fragment;+++[A0A087X1V2_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000484481}; Flags: Fragment;+++[A0A0C4DGS4_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000475074}; Flags: Fragment;+++[A0A0D9SF30_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000486241}; Flags: Fragment;+++[A0A0D9SF98_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000486406}; Flags: Fragment;+++[H7BYX6_HUMAN|Unreviewed]SubName: Full=Neural cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000384055};+++[L8EBH1_HUMAN|Unreviewed]SubName: Full=Alternative protein NCAM1 {ECO:0000313|EMBL:CCQ43918.1};+++[L8ECP3_HUMAN|Unreviewed]SubName: Full=Alternative protein NCAM1 {ECO:0000313|EMBL:CCQ43917.1};"]
[4701,"'NDUFA7'",794,681,737.5,"05016///Huntington's disease+++04723///Retrograde endocannabinoid signaling+++04714///Thermogenesis+++05012///Parkinson's disease+++00190///Oxidative phosphorylation+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01100///Metabolic pathways",null,"M00146///NADH dehydrogenase (ubiquinone) 1 alpha subcomplex",null,"GO:0005761///mitochondrial ribosome+++GO:0070469///respiratory chain+++GO:0016020///membrane+++GO:0005747///mitochondrial respiratory chain complex I+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion","GO:0008137///NADH dehydrogenase (ubiquinone) activity+++GO:0003735///structural constituent of ribosome","GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0055114///oxidation-reduction process+++GO:0042773///ATP synthesis coupled electron transport+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0032543///mitochondrial translation","IPR009947///NADH:ubiquinone oxidoreductase subunit B14.5a","[NDUA7_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7; AltName: Full=Complex I-B14.5a; Short=CI-B14.5a; AltName: Full=NADH-ubiquinone oxidoreductase subunit B14.5a;+++[M0R0N0_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 {ECO:0000313|Ensembl:ENSP00000471333};+++[M0R1K9_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 {ECO:0000313|Ensembl:ENSP00000471943};+++[Q32Q14_HUMAN|Unreviewed]SubName: Full=NDUFA7 protein {ECO:0000313|EMBL:AAI07893.1}; Flags: Fragment;+++[Q6FG42_HUMAN|Unreviewed]SubName: Full=NDUFA7 protein {ECO:0000313|EMBL:CAG47062.1}; Flags: Fragment;+++[Q6IB89_HUMAN|Unreviewed]SubName: Full=NDUFA7 protein {ECO:0000313|EMBL:CAG33196.1};"]
[4715,"'NDUFB9'",609,507,558,"04714///Thermogenesis+++04723///Retrograde endocannabinoid signaling+++05010///Alzheimer's disease+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++05016///Huntington's disease","H00473///Mitochondrial complex I deficiency","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0070469///respiratory chain+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0005747///mitochondrial respiratory chain complex I","GO:0005515///protein binding+++GO:0008137///NADH dehydrogenase (ubiquinone) activity","GO:0006120///mitochondrial electron transport, NADH to ubiquinone+++GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0055114///oxidation-reduction process+++GO:0007605///sensory perception of sound","IPR008011///Complex 1 LYR protein+++IPR033034///NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9","[NDUB9_HUMAN|Reviewed]RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; AltName: Full=Complex I-B22; Short=CI-B22; AltName: Full=LYR motif-containing protein 3; AltName: Full=NADH-ubiquinone oxidoreductase B22 subunit;+++[E7EWZ0_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 {ECO:0000313|Ensembl:ENSP00000428282};+++[E9PF49_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 {ECO:0000313|Ensembl:ENSP00000431115};+++[E9PH64_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 {ECO:0000313|Ensembl:ENSP00000430322};"]
[4733,"'DRG1'",582,384,483,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0000932///P-body+++GO:0016020///membrane+++GO:0005844///polysome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0016605///PML body","GO:0051213///dioxygenase activity+++GO:0042802///identical protein binding+++GO:0008565///protein transporter activity+++GO:0042803///protein homodimerization activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0046872///metal ion binding+++GO:0003729///mRNA binding+++GO:0005525///GTP binding+++GO:0003723///RNA binding","GO:0017148///negative regulation of translation+++GO:0045665///negative regulation of neuron differentiation+++GO:0019827///stem cell population maintenance+++GO:0010468///regulation of gene expression","IPR005225///Small GTP-binding protein domain+++IPR006074///GTP1/OBG, conserved site+++IPR031167///OBG-type guanine nucleotide-binding (G) domain+++IPR031662///GTP binding protein, second domain+++IPR004095///TGS+++IPR012675///Beta-grasp domain superfamily+++IPR012676///TGS-like+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR006073///GTP binding domain","[DRG1_HUMAN|Reviewed]RecName: Full=Developmentally-regulated GTP-binding protein 1; Short=DRG-1; AltName: Full=Neural precursor cell expressed developmentally down-regulated protein 3; Short=NEDD-3;"]
[4752,"'NEK3'",55,42,48.5,{"$nulls":4},"GO:0030424///axon+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0042995///cell projection","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity","GO:0006468///protein phosphorylation+++GO:0030010///establishment of cell polarity+++GO:0090043///regulation of tubulin deacetylation+++GO:0007049///cell cycle+++GO:0016310///phosphorylation+++GO:0048812///neuron projection morphogenesis+++GO:0000278///mitotic cell cycle+++GO:0051301///cell division","IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily","[NEK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase Nek3; EC=2.7.11.1; AltName: Full=HSPK 36; AltName: Full=Never in mitosis A-related kinase 3; Short=NimA-related protein kinase 3;+++[A0A087WY58_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek3 {ECO:0000313|Ensembl:ENSP00000481533};+++[A0A087X030_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek3 {ECO:0000313|Ensembl:ENSP00000483058}; Flags: Fragment;+++[A0A087X203_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek3 {ECO:0000313|Ensembl:ENSP00000484594};+++[F8VTT4_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek3 {ECO:0000313|Ensembl:ENSP00000447995};+++[F8VV00_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase Nek3 {ECO:0000313|Ensembl:ENSP00000449679}; Flags: Fragment;+++[G3V202_HUMAN|Unreviewed]SubName: Full=NIMA (Never in mitosis gene a)-related kinase 3, isoform CRA_d {ECO:0000313|EMBL:EAX08909.1};+++[Q6ZN64_HUMAN|Unreviewed]SubName: Full=NIMA (Never in mitosis gene a)-related kinase 3, isoform CRA_a {ECO:0000313|EMBL:EAX08905.1}; SubName: Full=cDNA FLJ16392 fis, clone TRACH2020048, moderately similar to Mus musculus serine/threonine-protein kinase NEK3 (Nek3) mRNA {ECO:0000313|EMBL:BAD18511.1};"]
[4753,"'NELL2'",941,1257,1099,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0002116///semaphorin receptor complex+++GO:0016021///integral component of membrane+++GO:0099055///integral component of postsynaptic membrane+++GO:0005576///extracellular region+++GO:0098978///glutamatergic synapse+++GO:0030424///axon+++GO:0005623///cell","GO:0019838///growth factor binding+++GO:0005509///calcium ion binding+++GO:0019955///cytokine binding+++GO:0005515///protein binding+++GO:0038023///signaling receptor activity+++GO:0005021///vascular endothelial growth factor-activated receptor activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0008201///heparin binding+++GO:0017154///semaphorin receptor activity","GO:0001525///angiogenesis+++GO:0007411///axon guidance+++GO:0003148///outflow tract septum morphogenesis+++GO:0021612///facial nerve structural organization+++GO:0061551///trigeminal ganglion development+++GO:0007275///multicellular organism development+++GO:1904835///dorsal root ganglion morphogenesis+++GO:1902285///semaphorin-plexin signaling pathway involved in neuron projection guidance+++GO:0001755///neural crest cell migration+++GO:0007507///heart development+++GO:0036486///ventral trunk neural crest cell migration+++GO:0021675///nerve development+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0010595///positive regulation of endothelial cell migration+++GO:0061549///sympathetic ganglion development+++GO:0016032///viral process+++GO:0001764///neuron migration+++GO:0097490///sympathetic neuron projection extension+++GO:1903375///facioacoustic ganglion development+++GO:1901166///neural crest cell migration involved in autonomic nervous system development+++GO:0007155///cell adhesion+++GO:0030154///cell differentiation+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0070050///neuron cellular homeostasis+++GO:0021649///vestibulocochlear nerve structural organization+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0021828///gonadotrophin-releasing hormone neuronal migration to the hypothalamus+++GO:0097491///sympathetic neuron projection guidance+++GO:0097374///sensory neuron axon guidance+++GO:0099175///regulation of postsynapse organization+++GO:0048846///axon extension involved in axon guidance+++GO:0050919///negative chemotaxis+++GO:0007399///nervous system development+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0071526///semaphorin-plexin signaling pathway","IPR018097///EGF-like calcium-binding, conserved site+++IPR001791///Laminin G domain+++IPR001881///EGF-like calcium-binding domain+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR024731///EGF domain+++IPR000742///EGF-like domain+++IPR013032///EGF-like, conserved site+++IPR001007///VWFC domain+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily","[NELL2_HUMAN|Reviewed]RecName: Full=Protein kinase C-binding protein NELL2; AltName: Full=NEL-like protein 2; AltName: Full=Nel-related protein 2; Flags: Precursor;+++[A0A024R0X1_HUMAN|Unreviewed]SubName: Full=NEL-like 2 (Chicken), isoform CRA_b {ECO:0000313|EMBL:EAW57875.1};+++[B7Z625_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55521, highly similar to Protein kinase C-binding protein NELL2 {ECO:0000313|EMBL:BAH13111.1};+++[F8VRQ0_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000448635};+++[F8VVB6_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000449332};+++[F8VXR5_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000449068}; Flags: Fragment;+++[F8VZ72_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000447384}; Flags: Fragment;+++[F8W1A2_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000447085}; Flags: Fragment;+++[F8W1I8_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000446961}; Flags: Fragment;+++[H0YHY5_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000448107}; Flags: Fragment;+++[H0YI34_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000448407}; Flags: Fragment;+++[H0YIT4_HUMAN|Unreviewed]SubName: Full=Protein kinase C-binding protein NELL2 {ECO:0000313|Ensembl:ENSP00000450102}; Flags: Fragment;+++[L0R6L1_HUMAN|Unreviewed]SubName: Full=Alternative protein NELL2 {ECO:0000313|EMBL:CCO13780.1};"]
[4779,"'NFE2L1'",11811,12186,11998.5,{"$nulls":4},"GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0003677///DNA binding+++GO:0044877///protein-containing complex binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0046982///protein heterodimerization activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003712///transcription coregulator activity+++GO:0005515///protein binding+++GO:0000979///RNA polymerase II core promoter sequence-specific DNA binding+++GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0008289///lipid binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0015485///cholesterol binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0001046///core promoter sequence-specific DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding","GO:0006629///lipid metabolic process+++GO:0007005///mitochondrion organization+++GO:0006783///heme biosynthetic process+++GO:0006366///transcription by RNA polymerase II+++GO:1901329///regulation of odontoblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006954///inflammatory response+++GO:0045454///cell redox homeostasis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0055088///lipid homeostasis+++GO:0042632///cholesterol homeostasis+++GO:0008203///cholesterol metabolic process+++GO:0036003///positive regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0097201///negative regulation of transcription from RNA polymerase II promoter in response to stress+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030218///erythrocyte differentiation+++GO:0006091///generation of precursor metabolites and energy+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008202///steroid metabolic process+++GO:0034599///cellular response to oxidative stress+++GO:0071397///cellular response to cholesterol+++GO:0009653///anatomical structure morphogenesis","IPR004827///Basic-leucine zipper domain+++IPR029847///Nuclear factor erythroid 2-related factor 1/NFE2L1+++IPR008917///Transcription factor, Skn-1-like, DNA-binding domain superfamily+++IPR004826///Basic leucine zipper domain, Maf-type","[NF2L1_HUMAN|Reviewed]RecName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000305}; AltName: Full=Locus control region-factor 1 {ECO:0000303|PubMed:8036168}; Short=LCR-F1 {ECO:0000303|PubMed:8036168}; AltName: Full=Nuclear factor erythroid 2-related factor 1; Short=NF-E2-related factor 1 {ECO:0000303|PubMed:16687406, ECO:0000303|PubMed:8248256}; Short=NFE2-related factor 1 {ECO:0000303|PubMed:16687406, ECO:0000303|PubMed:8248256}; AltName: Full=Nuclear factor, erythroid derived 2, like 1; AltName: Full=Protein NRF1, p120 form {ECO:0000303|PubMed:24448410}; AltName: Full=Transcription factor 11 {ECO:0000303|PubMed:8001966}; Short=TCF-11 {ECO:0000303|PubMed:8001966}; Contains: RecName: Full=Transcription factor NRF1 {ECO:0000305}; AltName: Full=Protein NRF1, p110 form {ECO:0000303|PubMed:24448410};+++[A0A0G2JLG9_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000462003}; Flags: Fragment;+++[A3KMG6_HUMAN|Unreviewed]SubName: Full=NFE2L1 protein {ECO:0000313|EMBL:AAI31770.1}; Flags: Fragment;+++[B4DYE1_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000464446}; SubName: Full=cDNA FLJ53241, highly similar to Nuclear factor erythroid 2-related factor 1 {ECO:0000313|EMBL:BAG63703.1};+++[F5H1B7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000445811};+++[J3KRF3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000461971}; Flags: Fragment;+++[J3KSE0_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000462444}; Flags: Fragment;+++[J3KSR3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000462610}; Flags: Fragment;+++[J3KTG6_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000462971}; Flags: Fragment;+++[J3QKY3_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000463291};+++[J3QLQ1_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000463657}; Flags: Fragment;+++[J3QQH8_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000463744}; Flags: Fragment;+++[J3QQQ1_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000463836}; Flags: Fragment;+++[J3QQY8_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000463960}; Flags: Fragment;+++[J3QR31_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000464018}; Flags: Fragment;+++[J3QRG7_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000464203}; Flags: Fragment;+++[J9JIE5_HUMAN|Unreviewed]SubName: Full=Endoplasmic reticulum membrane sensor NFE2L1 {ECO:0000313|Ensembl:ENSP00000355190};+++[Q8NF22_HUMAN|Unreviewed]SubName: Full=FLJ00380 protein {ECO:0000313|EMBL:BAC03440.1}; Flags: Fragment;"]
[4799,"'NFX1'",514,629,571.5,"05165///Human papillomavirus infection",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005829///cytosol","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008270///zinc ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0016740///transferase activity+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0016032///viral process+++GO:0045347///negative regulation of MHC class II biosynthetic process+++GO:0006954///inflammatory response","IPR034076///Transcriptional repressor NF-X1, R3H domain+++IPR000967///Zinc finger, NF-X1-type+++IPR001374///R3H domain+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR001841///Zinc finger, RING-type+++IPR019787///Zinc finger, PHD-finger+++IPR036867///R3H domain superfamily+++IPR034078///Transcription factor NFX1 family","[NFX1_HUMAN|Reviewed]RecName: Full=Transcriptional repressor NF-X1; EC=2.3.2.-; AltName: Full=Nuclear transcription factor, X box-binding protein 1;+++[A0JLR2_HUMAN|Unreviewed]SubName: Full=NFX1 protein {ECO:0000313|EMBL:AAH06447.1}; Flags: Fragment;+++[L8ECM9_HUMAN|Unreviewed]SubName: Full=Alternative protein NFX1 {ECO:0000313|EMBL:CCQ43847.1};"]
[482,"'ATP1B2'",30,18,24,"04918///Thyroid hormone synthesis+++04964///Proximal tubule bicarbonate reclamation+++04970///Salivary secretion+++04972///Pancreatic secretion+++04974///Protein digestion and absorption+++04022///cGMP-PKG signaling pathway+++04925///Aldosterone synthesis and secretion+++04919///Thyroid hormone signaling pathway+++04961///Endocrine and other factor-regulated calcium reabsorption+++04960///Aldosterone-regulated sodium reabsorption+++04260///Cardiac muscle contraction+++04976///Bile secretion+++04978///Mineral absorption+++04024///cAMP signaling pathway+++04911///Insulin secretion+++04261///Adrenergic signaling in cardiomyocytes+++04973///Carbohydrate digestion and absorption+++04971///Gastric acid secretion",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005890///sodium:potassium-exchanging ATPase complex+++GO:0005886///plasma membrane+++GO:0016324///apical plasma membrane","GO:0001671///ATPase activator activity+++GO:0005515///protein binding+++GO:0005391///sodium:potassium-exchanging ATPase activity+++GO:0051117///ATPase binding","GO:0010248///establishment or maintenance of transmembrane electrochemical gradient+++GO:0006811///ion transport+++GO:1903288///positive regulation of potassium ion import+++GO:0006814///sodium ion transport+++GO:0036376///sodium ion export across plasma membrane+++GO:0050900///leukocyte migration+++GO:0007155///cell adhesion+++GO:1903278///positive regulation of sodium ion export across plasma membrane+++GO:0030007///cellular potassium ion homeostasis+++GO:0086009///membrane repolarization+++GO:0050821///protein stabilization+++GO:1990573///potassium ion import across plasma membrane+++GO:0032781///positive regulation of ATPase activity+++GO:0086064///cell communication by electrical coupling involved in cardiac conduction+++GO:0006813///potassium ion transport+++GO:0006883///cellular sodium ion homeostasis+++GO:1901018///positive regulation of potassium ion transmembrane transporter activity","IPR038702///Sodium/potassium-transporting ATPase subunit beta superfamily+++IPR000402///Sodium/potassium-transporting ATPase subunit beta","[AT1B2_HUMAN|Reviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta-2; AltName: Full=Adhesion molecule in glia; Short=AMOG; AltName: Full=Sodium/potassium-dependent ATPase subunit beta-2;+++[I3L1V9_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099}; Flags: Fragment;+++[I3L3J8_HUMAN|Unreviewed]RecName: Full=Sodium/potassium-transporting ATPase subunit beta {ECO:0000256|RuleBase:RU362099}; Flags: Fragment;+++[Q58I19_HUMAN|Unreviewed]SubName: Full=Na+/K+ transporting ATPase beta 2 polypeptide {ECO:0000313|EMBL:AAX55912.1}; Flags: Fragment;"]
[4841,"'NONO'",7513,6742,7127.5,null,"H00658///Syndromic X-linked mental retardation",null,null,"GO:0016020///membrane+++GO:0016363///nuclear matrix+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0042382///paraspeckles+++GO:0005634///nucleus","GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0003682///chromatin binding+++GO:0070888///E-box binding+++GO:0003676///nucleic acid binding","GO:1903377///negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:0045087///innate immune response+++GO:0008380///RNA splicing+++GO:0007623///circadian rhythm+++GO:0002218///activation of innate immune response+++GO:0048511///rhythmic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006397///mRNA processing+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0002376///immune system process+++GO:0006281///DNA repair+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042752///regulation of circadian rhythm","IPR034558///p54nrb, RNA recognition motif 2+++IPR034552///p54nrb, RNA recognition motif 1+++IPR012975///NOPS+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain","[NONO_HUMAN|Reviewed]RecName: Full=Non-POU domain-containing octamer-binding protein; Short=NonO protein; AltName: Full=54 kDa nuclear RNA- and DNA-binding protein; AltName: Full=55 kDa nuclear protein; AltName: Full=DNA-binding p52/p100 complex, 52 kDa subunit; AltName: Full=NMT55; AltName: Full=p54(nrb); Short=p54nrb;+++[A0A0S2Z4E7_HUMAN|Unreviewed]SubName: Full=Non-POU domain containing octamer-binding isoform 2 {ECO:0000313|EMBL:ALQ33693.1};+++[A0A0S2Z4Z9_HUMAN|Unreviewed]SubName: Full=Non-POU domain containing octamer-binding isoform 1 {ECO:0000313|EMBL:ALQ33692.1}; Flags: Fragment;+++[C9IZL7_HUMAN|Unreviewed]SubName: Full=Non-POU domain-containing octamer-binding protein {ECO:0000313|Ensembl:ENSP00000406673}; Flags: Fragment;+++[C9J4X2_HUMAN|Unreviewed]SubName: Full=Non-POU domain-containing octamer-binding protein {ECO:0000313|Ensembl:ENSP00000410299}; Flags: Fragment;+++[C9JJ13_HUMAN|Unreviewed]SubName: Full=Non-POU domain-containing octamer-binding protein {ECO:0000313|Ensembl:ENSP00000415777}; Flags: Fragment;+++[C9JYS8_HUMAN|Unreviewed]SubName: Full=Non-POU domain-containing octamer-binding protein {ECO:0000313|Ensembl:ENSP00000413350}; Flags: Fragment;+++[H7C367_HUMAN|Unreviewed]SubName: Full=Non-POU domain-containing octamer-binding protein {ECO:0000313|Ensembl:ENSP00000409773}; Flags: Fragment;"]
[4862,"'NPAS2'",2182,1923,2052.5,"04710///Circadian rhythm",{"$nulls":3},"GO:0005667///transcription factor complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046983///protein dimerization activity+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0051879///Hsp90 protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006974///cellular response to DNA damage stimulus+++GO:0048511///rhythmic process+++GO:0007417///central nervous system development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060548///negative regulation of cell death+++GO:2001020///regulation of response to DNA damage stimulus+++GO:0032922///circadian regulation of gene expression+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007623///circadian rhythm+++GO:0051775///response to redox state+++GO:0019216///regulation of lipid metabolic process+++GO:0045739///positive regulation of DNA repair","IPR000014///PAS domain+++IPR001610///PAC motif+++IPR035965///PAS domain superfamily+++IPR001067///Nuclear translocator+++IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain+++IPR013767///PAS fold","[NPAS2_HUMAN|Reviewed]RecName: Full=Neuronal PAS domain-containing protein 2; Short=Neuronal PAS2; AltName: Full=Basic-helix-loop-helix-PAS protein MOP4; AltName: Full=Class E basic helix-loop-helix protein 9; Short=bHLHe9; AltName: Full=Member of PAS protein 4; AltName: Full=PAS domain-containing protein 4;+++[A0PJF9_HUMAN|Unreviewed]SubName: Full=NPAS2 protein {ECO:0000313|EMBL:AAH28107.1}; Flags: Fragment;+++[A2I2P5_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain protein 2 {ECO:0000313|EMBL:ABM64214.1};+++[D3DVJ3_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX01833.1};+++[H7BZA3_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000388528}; Flags: Fragment;+++[H7BZY5_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000392125}; Flags: Fragment;+++[H7C080_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393396}; Flags: Fragment;+++[H7C0J4_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000395265}; Flags: Fragment;+++[H7C0Z2_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000397595}; Flags: Fragment;+++[X5DR62_HUMAN|Unreviewed]SubName: Full=Neuronal PAS domain protein 2 isoform A {ECO:0000313|EMBL:AHW56532.1}; SubName: Full=Neuronal PAS domain protein 2, isoform CRA_e {ECO:0000313|EMBL:EAX01835.1}; Flags: Fragment;"]
[489,"'ATP2A3'",13,18,15.5,"04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04972///Pancreatic secretion+++05010///Alzheimer's disease","H00755///Acrokeratosis verruciformis+++H01129///Brody myopathy+++H00715///Darier disease",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0031095///platelet dense tubular network membrane+++GO:0016529///sarcoplasmic reticulum+++GO:0031965///nuclear membrane+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0005388///calcium-transporting ATPase activity+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity","GO:0070588///calcium ion transmembrane transport+++GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034220///ion transmembrane transport+++GO:1903779///regulation of cardiac conduction+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0006874///cellular calcium ion homeostasis+++GO:1902600///proton transmembrane transport","IPR030330///Sarcoplasmic/endoplasmic reticulum calcium ATPase 3+++IPR023214///HAD superfamily+++IPR023299///P-type ATPase, cytoplasmic domain N+++IPR018303///P-type ATPase, phosphorylation site+++IPR004014///Cation-transporting P-type ATPase, N-terminal+++IPR001757///P-type ATPase+++IPR023298///P-type ATPase, transmembrane domain superfamily+++IPR006068///Cation-transporting P-type ATPase, C-terminal+++IPR008250///P-type ATPase, A domain superfamily+++IPR036412///HAD-like superfamily+++IPR005782///P-type ATPase, subfamily  IIA, SERCA-type","[AT2A3_HUMAN|Reviewed]RecName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; Short=SERCA3; Short=SR Ca(2+)-ATPase 3; EC=3.6.3.8; AltName: Full=Calcium pump 3;+++[A0A0C4DGN1_HUMAN|Unreviewed]SubName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 {ECO:0000313|Ensembl:ENSP00000458865}; Flags: Fragment;+++[A0A0C4DGN3_HUMAN|Unreviewed]SubName: Full=Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 {ECO:0000313|Ensembl:ENSP00000461480}; Flags: Fragment;+++[A8K9K1_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};"]
[4909,"'NTF4'",7,9,8,"04722///Neurotrophin signaling pathway+++04014///Ras signaling pathway+++04010///MAPK signaling pathway+++04151///PI3K-Akt signaling pathway","H00612///Primary open angle glaucoma",null,null,"GO:0005615///extracellular space+++GO:0031410///cytoplasmic vesicle+++GO:0030424///axon+++GO:0008021///synaptic vesicle+++GO:0005576///extracellular region+++GO:0030425///dendrite","GO:0008083///growth factor activity+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0048812///neuron projection morphogenesis+++GO:0007202///activation of phospholipase C activity+++GO:0008544///epidermis development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0008052///sensory organ boundary specification+++GO:0007613///memory+++GO:0042490///mechanoreceptor differentiation+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007402///ganglion mother cell fate determination+++GO:0061193///taste bud development+++GO:0007616///long-term memory+++GO:0060384///innervation+++GO:0021675///nerve development+++GO:0038180///nerve growth factor signaling pathway+++GO:0060548///negative regulation of cell death+++GO:0007422///peripheral nervous system development+++GO:0010469///regulation of signaling receptor activity+++GO:0008344///adult locomotory behavior+++GO:0045664///regulation of neuron differentiation","IPR002072///Nerve growth factor-related+++IPR029034///Cystine-knot cytokine+++IPR019846///Nerve growth factor conserved site+++IPR020432///Neurotrophin-4+++IPR020408///Nerve growth factor-like","[NTF4_HUMAN|Reviewed]RecName: Full=Neurotrophin-4; Short=NT-4; AltName: Full=Neurotrophin-5; Short=NT-5; AltName: Full=Neutrophic factor 4; Flags: Precursor;+++[A0A024QZE4_HUMAN|Unreviewed]SubName: Full=Neurotrophin 5 (Neurotrophin 4/5), isoform CRA_a {ECO:0000313|EMBL:EAW52442.1};+++[M0R0X2_HUMAN|Unreviewed]SubName: Full=Neurotrophin-4 {ECO:0000313|Ensembl:ENSP00000471508}; Flags: Fragment;"]
[4927,"'NUP88'",345,358,351.5,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005623///cell+++GO:0005643///nuclear pore","GO:0017056///structural constituent of nuclear pore+++GO:0005215///transporter activity","GO:0000278///mitotic cell cycle+++GO:0051028///mRNA transport+++GO:0000056///ribosomal small subunit export from nucleus+++GO:0015031///protein transport+++GO:0000055///ribosomal large subunit export from nucleus+++GO:0016032///viral process+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0006913///nucleocytoplasmic transport+++GO:0006611///protein export from nucleus","IPR019321///Nucleoporin Nup88+++IPR037700///Nucleoporin NUP88/NUP82","[NUP88_HUMAN|Reviewed]RecName: Full=Nuclear pore complex protein Nup88; AltName: Full=88 kDa nucleoporin; AltName: Full=Nucleoporin Nup88;+++[B4DP20_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58372, highly similar to Nuclear pore complex protein Nup88 {ECO:0000313|EMBL:BAG60432.1};+++[I3L245_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup88 {ECO:0000313|Ensembl:ENSP00000459370}; Flags: Fragment;+++[I3L2W3_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup88 {ECO:0000313|Ensembl:ENSP00000459979};+++[I3L4K7_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup88 {ECO:0000313|Ensembl:ENSP00000461334}; Flags: Fragment;+++[J3KMX1_HUMAN|Unreviewed]SubName: Full=Nuclear pore complex protein Nup88 {ECO:0000313|Ensembl:ENSP00000225696}; Flags: Fragment;"]
[494143,"'CHAC2'",15,13,14,"01100///Metabolic pathways+++00480///Glutathione metabolism",null,null,"R11861///glutathione gamma-glutamyl cyclotransferase (5-oxoproline-forming)   Glutathione <=> Cys-Gly + 5-Oxoproline","GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005575///cellular_component","GO:0061928///glutathione specific gamma-glutamylcyclotransferase activity+++GO:0003839///gamma-glutamylcyclotransferase activity+++GO:0003674///molecular_function+++GO:0016829///lyase activity","GO:0008150///biological_process+++GO:0006750///glutathione biosynthetic process+++GO:0006751///glutathione catabolic process","IPR036568///Gamma-glutamyl cyclotransferase-like superfamily+++IPR013024///Gamma-glutamyl cyclotransferase-like+++IPR006840///Glutathione-specific gamma-glutamylcyclotransferase","[CHAC2_HUMAN|Reviewed]RecName: Full=Glutathione-specific gamma-glutamylcyclotransferase 2 {ECO:0000303|PubMed:27913623}; Short=Gamma-GCG 2 {ECO:0000305}; EC=4.3.2.7 {ECO:0000269|PubMed:27913623}; AltName: Full=Cation transport regulator-like protein 2 {ECO:0000250|UniProtKB:Q9BUX1};"]
[497190,"'CLEC18B'",149.18,127.79,138.485,{"$nulls":4},"GO:0016529///sarcoplasmic reticulum+++GO:0005783///endoplasmic reticulum+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005768///endosome+++GO:0005794///Golgi apparatus","GO:0030247///polysaccharide binding+++GO:0030246///carbohydrate binding",null,"IPR035940///CAP superfamily+++IPR001304///C-type lectin-like+++IPR013032///EGF-like, conserved site+++IPR001283///Cysteine-rich  secretory protein, allergen V5/Tpx-1-related+++IPR000742///EGF-like domain+++IPR016187///C-type lectin fold+++IPR014044///CAP domain+++IPR018378///C-type lectin, conserved site+++IPR016186///C-type lectin-like/link domain superfamily","[CL18B_HUMAN|Reviewed]RecName: Full=C-type lectin domain family 18 member B; AltName: Full=Mannose receptor-like protein 1; Flags: Precursor;+++[A0A087WT46_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 18 member B {ECO:0000313|Ensembl:ENSP00000477577};+++[A0A087X0Q5_HUMAN|Unreviewed]SubName: Full=C-type lectin domain family 18 member B {ECO:0000313|Ensembl:ENSP00000483587};"]
[4998,"'ORC1'",7,3,5,"04110///Cell cycle+++04113///Meiosis - yeast+++04111///Cell cycle - yeast","H00464///Patella dysplasias+++H01889///Meier-Gorlin syndrome","M00284///Origin recognition complex",null,"GO:0005829///cytosol+++GO:0005664///nuclear origin of replication recognition complex+++GO:0005730///nucleolus+++GO:0005886///plasma membrane+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000808///origin recognition complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0005524///ATP binding","GO:0006270///DNA replication initiation+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006260///DNA replication","IPR003959///ATPase, AAA-type, core+++IPR015163///Cdc6, C-terminal+++IPR003593///AAA+ ATPase domain+++IPR001025///Bromo adjacent homology (BAH) domain+++IPR020793///Origin recognition complex, subunit 1+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[ORC1_HUMAN|Reviewed]RecName: Full=Origin recognition complex subunit 1; AltName: Full=Replication control protein 1;+++[B7Z8H0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61742, highly similar to Origin recognition complex subunit 1 {ECO:0000313|EMBL:BAH13956.1};+++[Q96F82_HUMAN|Unreviewed]SubName: Full=Origin recognition complex, subunit 1-like (Yeast) {ECO:0000313|EMBL:AAH11539.1};"]
[5018,"'OXA1L'",2225,2126,2175.5,"02024///Quorum sensing+++03060///Protein export+++03070///Bacterial secretion system",null,"M00335///Sec (secretion) system",null,"GO:0032991///protein-containing complex+++GO:0031966///mitochondrial membrane+++GO:0005746///mitochondrial respiratory chain+++GO:0016020///membrane+++GO:0005759///mitochondrial matrix+++GO:0005743///mitochondrial inner membrane+++GO:0032592///integral component of mitochondrial membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0032977///membrane insertase activity+++GO:0042803///protein homodimerization activity+++GO:0097177///mitochondrial ribosome binding","GO:0032981///mitochondrial respiratory chain complex I assembly+++GO:0065003///protein-containing complex assembly+++GO:0033615///mitochondrial proton-transporting ATP synthase complex assembly+++GO:0070126///mitochondrial translational termination+++GO:0032780///negative regulation of ATPase activity+++GO:0051262///protein tetramerization+++GO:0070125///mitochondrial translational elongation+++GO:0009060///aerobic respiration+++GO:0015031///protein transport+++GO:0051354///negative regulation of oxidoreductase activity+++GO:0055114///oxidation-reduction process","IPR028055///Membrane insertase YidC/Oxa1, C-terminal+++IPR001708///Membrane  insertase YidC/ALB3/OXA1/COX18","[OXA1L_HUMAN|Reviewed]RecName: Full=Mitochondrial inner membrane protein OXA1L; AltName: Full=Hsa; AltName: Full=OXA1Hs; AltName: Full=Oxidase assembly 1-like protein; Short=OXA1-like protein; Flags: Precursor;+++[C9JC63_HUMAN|Unreviewed]SubName: Full=Mitochondrial inner membrane protein OXA1L {ECO:0000313|Ensembl:ENSP00000396596}; Flags: Fragment;+++[E7EVY0_HUMAN|Unreviewed]SubName: Full=Mitochondrial inner membrane protein OXA1L {ECO:0000313|Ensembl:ENSP00000387601};+++[H7BZE6_HUMAN|Unreviewed]SubName: Full=Mitochondrial inner membrane protein OXA1L {ECO:0000313|Ensembl:ENSP00000389240}; Flags: Fragment;+++[J3KNA0_HUMAN|Unreviewed]SubName: Full=Mitochondrial inner membrane protein OXA1L {ECO:0000313|Ensembl:ENSP00000285848};+++[Q2M1J6_HUMAN|Unreviewed]SubName: Full=Oxidase (Cytochrome c) assembly 1-like {ECO:0000313|EMBL:AAI12332.1};+++[S4R3Q9_HUMAN|Unreviewed]SubName: Full=Mitochondrial inner membrane protein OXA1L {ECO:0000313|Ensembl:ENSP00000474623};"]
[5037,"'PEBP1'",4203,3147,3675,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0045177///apical part of cell+++GO:0005634///nucleus+++GO:0005615///extracellular space+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0043679///axon terminus+++GO:0043025///neuronal cell body+++GO:0043209///myelin sheath+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0008021///synaptic vesicle+++GO:0005737///cytoplasm","GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008289///lipid binding+++GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0030414///peptidase inhibitor activity+++GO:0019899///enzyme binding+++GO:0008429///phosphatidylethanolamine binding+++GO:0004867///serine-type endopeptidase inhibitor activity+++GO:0051019///mitogen-activated protein kinase binding+++GO:0019901///protein kinase binding+++GO:0005102///signaling receptor binding","GO:0007568///aging+++GO:0009636///response to toxic substance+++GO:0021766///hippocampus development+++GO:0006979///response to oxidative stress+++GO:0051591///response to cAMP+++GO:0048240///sperm capacitation+++GO:0014823///response to activity+++GO:0010243///response to organonitrogen compound+++GO:0060409///positive regulation of acetylcholine metabolic process+++GO:0009408///response to heat+++GO:0010951///negative regulation of endopeptidase activity+++GO:0045471///response to ethanol+++GO:0001505///regulation of neurotransmitter levels+++GO:0051592///response to calcium ion+++GO:0051412///response to corticosterone+++GO:0009611///response to wounding+++GO:0045840///positive regulation of mitotic nuclear division+++GO:0002026///regulation of the force of heart contraction+++GO:0043409///negative regulation of MAPK cascade+++GO:0043950///positive regulation of cAMP-mediated signaling+++GO:0000165///MAPK cascade+++GO:0010466///negative regulation of peptidase activity","IPR008914///Phosphatidylethanolamine-binding protein+++IPR036610///PEBP-like superfamily+++IPR035810///Phosphatidylethanolamine-binding protein, eukaryotic+++IPR001858///Phosphatidylethanolamine-binding, conserved site","[PEBP1_HUMAN|Reviewed]RecName: Full=Phosphatidylethanolamine-binding protein 1; Short=PEBP-1; AltName: Full=HCNPpp; AltName: Full=Neuropolypeptide h3; AltName: Full=Prostatic-binding protein; AltName: Full=Raf kinase inhibitor protein; Short=RKIP; Contains: RecName: Full=Hippocampal cholinergic neurostimulating peptide; Short=HCNP;+++[A0A0K0K1J6_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 96 {ECO:0000313|EMBL:ACV87193.1}; Flags: Fragment;+++[D9IAI1_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 34 {ECO:0000313|EMBL:ACJ13697.1}; SubName: Full=Phosphatidylethanolamine binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW98123.1}; SubName: Full=Phosphatidylethanolamine-binding protein 1 {ECO:0000313|EMBL:ADI99998.1};+++[V9HW05_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 210 {ECO:0000313|EMBL:ACF94504.1};"]
[50507,"'NOX4'",269,358,313.5,"04933///AGE-RAGE signaling pathway in diabetic complications",{"$nulls":3},"GO:0043020///NADPH oxidase complex+++GO:0016021///integral component of membrane+++GO:0005730///nucleolus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0097038///perinuclear endoplasmic reticulum+++GO:0016324///apical plasma membrane+++GO:0030054///cell junction+++GO:0005634///nucleus+++GO:0001725///stress fiber+++GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0005886///plasma membrane+++GO:0071944///cell periphery+++GO:0005739///mitochondrion","GO:0016491///oxidoreductase activity+++GO:0050664///oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor+++GO:0016174///NAD(P)H oxidase activity+++GO:0016175///superoxide-generating NADPH oxidase activity+++GO:0000166///nucleotide binding+++GO:0009055///electron transfer activity+++GO:0020037///heme binding+++GO:0005515///protein binding+++GO:0072341///modified amino acid binding+++GO:0019826///oxygen sensor activity+++GO:1990782///protein tyrosine kinase binding+++GO:0050660///flavin adenine dinucleotide binding","GO:0072593///reactive oxygen species metabolic process+++GO:0071320///cellular response to cAMP+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0050667///homocysteine metabolic process+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0071480///cellular response to gamma radiation+++GO:0071333///cellular response to glucose stimulus+++GO:0006954///inflammatory response+++GO:0022900///electron transport chain+++GO:0003015///heart process+++GO:0055007///cardiac muscle cell differentiation+++GO:0007568///aging+++GO:0042554///superoxide anion generation+++GO:1903409///reactive oxygen species biosynthetic process+++GO:2000573///positive regulation of DNA biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0006801///superoxide metabolic process+++GO:2000379///positive regulation of reactive oxygen species metabolic process+++GO:0051496///positive regulation of stress fiber assembly+++GO:0010467///gene expression+++GO:0043065///positive regulation of apoptotic process+++GO:0034599///cellular response to oxidative stress+++GO:0061098///positive regulation of protein tyrosine kinase activity+++GO:0045453///bone resorption+++GO:0001666///response to hypoxia+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0043406///positive regulation of MAP kinase activity+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0000902///cell morphogenesis+++GO:0055114///oxidation-reduction process+++GO:0007569///cell aging","IPR017938///Riboflavin synthase-like beta-barrel+++IPR000778///Cytochrome b245, heavy chain+++IPR013130///Ferric reductase transmembrane component-like domain+++IPR013121///Ferric reductase, NAD binding domain+++IPR017927///FAD-binding domain, ferredoxin reductase-type+++IPR039261///Ferredoxin-NADP reductase (FNR), nucleotide-binding domain+++IPR013112///FAD-binding 8","[NOX4_HUMAN|Reviewed]RecName: Full=NADPH oxidase 4; EC=1.6.3.-; AltName: Full=Kidney oxidase-1; Short=KOX-1; AltName: Full=Kidney superoxide-producing NADPH oxidase; AltName: Full=Renal NAD(P)H-oxidase;+++[B3KQ17_HUMAN|Unreviewed]SubName: Full=cDNA FLJ32627 fis, clone SYNOV1000049, highly similar to NADPH oxidase 4 {ECO:0000313|EMBL:BAG51879.1};+++[B7Z523_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51025, highly similar to NADPH oxidase 4 {ECO:0000313|EMBL:BAH12759.1};+++[B7Z529_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51027, highly similar to NADPH oxidase 4 {ECO:0000313|EMBL:BAH12765.1};+++[E9PI95_HUMAN|Unreviewed]SubName: Full=NADPH oxidase 4 {ECO:0000313|Ensembl:ENSP00000436716};+++[E9PPP2_HUMAN|Unreviewed]SubName: Full=NADPH oxidase 4 {ECO:0000313|Ensembl:ENSP00000436970};+++[E9PR43_HUMAN|Unreviewed]SubName: Full=NADPH oxidase 4 {ECO:0000313|Ensembl:ENSP00000436093};"]
[5062,"'PAK2'",841,1181,1011,"04660///T cell receptor signaling pathway+++04014///Ras signaling pathway+++05211///Renal cell carcinoma+++04810///Regulation of actin cytoskeleton+++04360///Axon guidance+++04010///MAPK signaling pathway+++04012///ErbB signaling pathway+++04510///Focal adhesion",{"$nulls":3},"GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0005634///nucleus+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0031267///small GTPase binding+++GO:0004672///protein kinase activity+++GO:0019901///protein kinase binding+++GO:0030296///protein tyrosine kinase activator activity+++GO:0005524///ATP binding+++GO:0048365///Rac GTPase binding+++GO:0042802///identical protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0045296///cadherin binding","GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0006915///apoptotic process+++GO:0006468///protein phosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0040008///regulation of growth+++GO:0071407///cellular response to organic cyclic compound+++GO:0007346///regulation of mitotic cell cycle+++GO:0060996///dendritic spine development+++GO:0050690///regulation of defense response to virus by virus+++GO:0016310///phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0006469///negative regulation of protein kinase activity+++GO:0050852///T cell receptor signaling pathway+++GO:0031295///T cell costimulation+++GO:0046777///protein autophosphorylation+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:2001271///negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis+++GO:2001238///positive regulation of extrinsic apoptotic signaling pathway+++GO:0030036///actin cytoskeleton organization+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0043408///regulation of MAPK cascade+++GO:0023014///signal transduction by protein phosphorylation+++GO:0007266///Rho protein signal transduction+++GO:0007165///signal transduction+++GO:0016477///cell migration","IPR000095///CRIB domain+++IPR035065///Serine/threonine-protein kinase PAK2/3+++IPR035064///p21-activated kinase 2, catalytic domain+++IPR000719///Protein kinase domain+++IPR036936///CRIB domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR033923///p21 activated kinase binding domain","[PAK2_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase PAK 2; EC=2.7.11.1; AltName: Full=Gamma-PAK; AltName: Full=PAK65; AltName: Full=S6/H4 kinase; AltName: Full=p21-activated kinase 2; Short=PAK-2; AltName: Full=p58; Contains: RecName: Full=PAK-2p27; Short=p27; Contains: RecName: Full=PAK-2p34; Short=p34; AltName: Full=C-t-PAK2;+++[A8K5M4_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00977200}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00977200};"]
[5071,"'PRKN'",25.05,34.95,30,"04120///Ubiquitin mediated proteolysis+++04137///Mitophagy - animal+++04141///Protein processing in endoplasmic reticulum+++05012///Parkinson's disease","H00344///Leprosy+++H00057///Parkinson's disease (PD)+++H01600///Parkinsonian syndrome",null,null,"GO:0005737///cytoplasm+++GO:0071797///LUBAC complex+++GO:0099073///mitochondrion-derived vesicle+++GO:0043005///neuron projection+++GO:0097413///Lewy body+++GO:0019005///SCF ubiquitin ligase complex+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0098793///presynapse+++GO:0005794///Golgi apparatus+++GO:0016235///aggresome+++GO:1990452///Parkin-FBXW7-Cul1 ubiquitin ligase complex+++GO:0016607///nuclear speck+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0000151///ubiquitin ligase complex","GO:0031625///ubiquitin protein ligase binding+++GO:0017124///SH3 domain binding+++GO:0043130///ubiquitin binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0051087///chaperone binding+++GO:1990444///F-box domain binding+++GO:0008013///beta-catenin binding+++GO:0019901///protein kinase binding+++GO:0046872///metal ion binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0001664///G protein-coupled receptor binding+++GO:0003779///actin binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031072///heat shock protein binding+++GO:0097602///cullin family protein binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding+++GO:0042826///histone deacetylase binding+++GO:0016740///transferase activity+++GO:0015631///tubulin binding+++GO:0042802///identical protein binding+++GO:0019899///enzyme binding+++GO:0016874///ligase activity+++GO:0019900///kinase binding+++GO:0030165///PDZ domain binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0004842///ubiquitin-protein transferase activity+++GO:0043274///phospholipase binding+++GO:0030544///Hsp70 protein binding+++GO:0005515///protein binding","GO:1902283///negative regulation of primary amine oxidase activity+++GO:0042415///norepinephrine metabolic process+++GO:0035249///synaptic transmission, glutamatergic+++GO:1901215///negative regulation of neuron death+++GO:0043388///positive regulation of DNA binding+++GO:0034620///cellular response to unfolded protein+++GO:0001964///startle response+++GO:0036503///ERAD pathway+++GO:0070979///protein K11-linked ubiquitination+++GO:0016579///protein deubiquitination+++GO:1903861///positive regulation of dendrite extension+++GO:0006513///protein monoubiquitination+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:1904049///negative regulation of spontaneous neurotransmitter secretion+++GO:0007612///learning+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:1900407///regulation of cellular response to oxidative stress+++GO:1905477///positive regulation of protein localization to membrane+++GO:0044314///protein K27-linked ubiquitination+++GO:0035519///protein K29-linked ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1903351///cellular response to dopamine+++GO:0010628///positive regulation of gene expression+++GO:0050821///protein stabilization+++GO:1903202///negative regulation of oxidative stress-induced cell death+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0046928///regulation of neurotransmitter secretion+++GO:0042053///regulation of dopamine metabolic process+++GO:0016236///macroautophagy+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:0046676///negative regulation of insulin secretion+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:0001963///synaptic transmission, dopaminergic+++GO:0045732///positive regulation of protein catabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0019538///protein metabolic process+++GO:0051881///regulation of mitochondrial membrane potential+++GO:1903265///positive regulation of tumor necrosis factor-mediated signaling pathway+++GO:1903377///negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0051583///dopamine uptake involved in synaptic transmission+++GO:0034976///response to endoplasmic reticulum stress+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0000423///mitophagy+++GO:0006979///response to oxidative stress+++GO:0032232///negative regulation of actin filament bundle assembly+++GO:0010498///proteasomal protein catabolic process+++GO:0032092///positive regulation of protein binding+++GO:0008344///adult locomotory behavior+++GO:0010636///positive regulation of mitochondrial fusion+++GO:0099074///mitochondrion to lysosome transport+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0010994///free ubiquitin chain polymerization+++GO:0070534///protein K63-linked ubiquitination+++GO:0001933///negative regulation of protein phosphorylation+++GO:0010821///regulation of mitochondrion organization+++GO:0070842///aggresome assembly+++GO:1903382///negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway+++GO:2000378///negative regulation of reactive oxygen species metabolic process+++GO:1905366///negative regulation of intralumenal vesicle formation+++GO:1902530///positive regulation of protein linear polyubiquitination+++GO:0085020///protein K6-linked ubiquitination+++GO:0007417///central nervous system development+++GO:0071287///cellular response to manganese ion+++GO:0044267///cellular protein metabolic process+++GO:0031647///regulation of protein stability+++GO:0098779///positive regulation of mitophagy in response to mitochondrial depolarization+++GO:0044257///cellular protein catabolic process+++GO:0070585///protein localization to mitochondrion+++GO:0032368///regulation of lipid transport+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0050804///modulation of chemical synaptic transmission+++GO:0031648///protein destabilization+++GO:0046329///negative regulation of JNK cascade+++GO:0000209///protein polyubiquitination+++GO:0006914///autophagy+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0010506///regulation of autophagy+++GO:0060828///regulation of canonical Wnt signaling pathway+++GO:0055069///zinc ion homeostasis+++GO:0090141///positive regulation of mitochondrial fission+++GO:0044828///negative regulation by host of viral genome replication+++GO:0010906///regulation of glucose metabolic process+++GO:0031396///regulation of protein ubiquitination+++GO:0010637///negative regulation of mitochondrial fusion+++GO:1902803///regulation of synaptic vesicle transport+++GO:0000266///mitochondrial fission+++GO:0042417///dopamine metabolic process+++GO:1903599///positive regulation of autophagy of mitochondrion+++GO:0007626///locomotory behavior+++GO:0051865///protein autoubiquitination+++GO:0033132///negative regulation of glucokinase activity+++GO:1903542///negative regulation of exosomal secretion+++GO:0007005///mitochondrion organization+++GO:0014059///regulation of dopamine secretion+++GO:0000422///autophagy of mitochondrion+++GO:0016567///protein ubiquitination+++GO:0060548///negative regulation of cell death+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010629///negative regulation of gene expression+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0070050///neuron cellular homeostasis+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0097237///cellular response to toxic substance+++GO:1905281///positive regulation of retrograde transport, endosome to Golgi+++GO:0051582///positive regulation of neurotransmitter uptake","IPR029071///Ubiquitin-like domain superfamily+++IPR019956///Ubiquitin+++IPR003977///E3 ubiquitin-protein ligase parkin+++IPR002867///IBR domain+++IPR000626///Ubiquitin domain+++IPR031127///E3 ubiquitin ligase RBR family","[PRKN_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase parkin {ECO:0000305}; Short=Parkin; EC=2.3.2.31 {ECO:0000269|PubMed:23770887}; AltName: Full=Parkin RBR E3 ubiquitin-protein ligase {ECO:0000312|HGNC:HGNC:8607}; AltName: Full=Parkinson juvenile disease protein 2; Short=Parkinson disease protein 2;+++[A0A087WU39_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase parkin {ECO:0000313|Ensembl:ENSP00000478353};+++[A0A087WX46_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase parkin {ECO:0000313|Ensembl:ENSP00000480716};+++[A0A087X0Z9_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};+++[A0A087X1E2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase parkin {ECO:0000313|Ensembl:ENSP00000484112};+++[A0A0S2Z446_HUMAN|Unreviewed]SubName: Full=Parkinson disease (Autosomal recessive, juvenile) 2, parkin, isoform CRA_b {ECO:0000313|EMBL:EAW47572.1}; SubName: Full=Parkinson protein 2 E3 ubiquitin protein ligase isoform 1 {ECO:0000313|EMBL:ALQ33698.1}; Flags: Fragment;+++[A0A0S2Z447_HUMAN|Unreviewed]SubName: Full=Parkinson protein 2 E3 ubiquitin protein ligase isoform 3 {ECO:0000313|EMBL:ALQ33700.1}; Flags: Fragment;+++[A0A1W5XGD7_HUMAN|Unreviewed]SubName: Full=Parkin RBR E3 ubiquitin protein ligase {ECO:0000313|EMBL:ARH59653.1}; Flags: Fragment;+++[A0A1W5XGE1_HUMAN|Unreviewed]SubName: Full=Parkin RBR E3 ubiquitin protein ligase {ECO:0000313|EMBL:ARH59655.1}; Flags: Fragment;+++[A0A1W5XGE7_HUMAN|Unreviewed]SubName: Full=Parkin RBR E3 ubiquitin protein ligase {ECO:0000313|EMBL:ARH59656.1}; Flags: Fragment;+++[B1AKC3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase parkin {ECO:0000313|Ensembl:ENSP00000355858}; SubName: Full=Parkinson protein 2 E3 ubiquitin protein ligase isoform 2 {ECO:0000313|EMBL:ALQ33699.1};+++[D3JZW5_HUMAN|Unreviewed]SubName: Full=Truncated parkin variant SV4,8DEL {ECO:0000313|EMBL:ADB91978.1}; SubName: Full=Truncated parkin variant SV4DEL {ECO:0000313|EMBL:ADB90269.1}; EC=6.3.2.19 {ECO:0000313|EMBL:ADB90269.1, ECO:0000313|EMBL:ADB91978.1};+++[D3K2X1_HUMAN|Unreviewed]SubName: Full=Truncated parkin variant SV3,8,9DEL {ECO:0000313|EMBL:ADB91980.1}; EC=6.3.2.19 {ECO:0000313|EMBL:ADB91980.1};+++[D3K2X2_HUMAN|Unreviewed]SubName: Full=Truncated parkin variant SV1bINS {ECO:0000313|EMBL:ADB91981.1}; EC=6.3.2.19 {ECO:0000313|EMBL:ADB91981.1};+++[M4T2U2_HUMAN|Unreviewed]SubName: Full=PARK2 splice variant {ECO:0000313|EMBL:AGH62056.1};+++[M4T4F2_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};+++[Q5XNR7_HUMAN|Unreviewed]SubName: Full=Parkin {ECO:0000313|EMBL:AAU93632.1}; Flags: Fragment;+++[Q5XNR8_HUMAN|Unreviewed]SubName: Full=Parkin {ECO:0000313|EMBL:AAU93631.1}; Flags: Fragment;+++[Q6Q2I7_HUMAN|Unreviewed]SubName: Full=Parkin {ECO:0000313|EMBL:AAS88421.1}; Flags: Fragment;+++[Q6Q2I8_HUMAN|Unreviewed]SubName: Full=Parkin {ECO:0000313|EMBL:AAS88420.1}; Flags: Fragment;+++[Q6S8G7_HUMAN|Unreviewed]SubName: Full=Parkin {ECO:0000313|EMBL:AAR27057.1}; Flags: Fragment;+++[S4X465_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474};+++[X5DNX0_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;+++[X5DR79_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;"]
[50814,"'NSDHL'",516,351,433.5,"00100///Steroid biosynthesis+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways","H00496///Congenital hemidysplasia with ichthyosiform nevus and limb defects (CHILD)+++H01917///CK syndrome","M00101///Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol","R07494///4alpha-Methylzymosterol-4-carboxylate + NADP+ <=> 3-Keto-4-methylzymosterol + NADPH + H+ + CO2","GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005811///lipid droplet","GO:0103066///4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity+++GO:0016491///oxidoreductase activity+++GO:0000252///C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity+++GO:0047012///sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity+++GO:0003854///3-beta-hydroxy-delta5-steroid dehydrogenase activity+++GO:0016616///oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor+++GO:0103067///4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity","GO:0006629///lipid metabolic process+++GO:0016126///sterol biosynthetic process+++GO:0001942///hair follicle development+++GO:0008202///steroid metabolic process+++GO:0007224///smoothened signaling pathway+++GO:0006695///cholesterol biosynthetic process+++GO:0008203///cholesterol metabolic process+++GO:0060716///labyrinthine layer blood vessel development+++GO:0055114///oxidation-reduction process+++GO:0006694///steroid biosynthetic process","IPR036291///NAD(P)-binding domain superfamily+++IPR002225///3-beta hydroxysteroid dehydrogenase/isomerase","[NSDHL_HUMAN|Reviewed]RecName: Full=Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; EC=1.1.1.170; AltName: Full=Protein H105e3;+++[C9JDR0_HUMAN|Unreviewed]SubName: Full=Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating {ECO:0000313|Ensembl:ENSP00000396266}; Flags: Fragment;"]
[50865,"'HEBP1'",439,331,385,{"$nulls":4},"GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm","GO:0020037///heme binding","GO:0007623///circadian rhythm+++GO:0007186///G protein-coupled receptor signaling pathway","IPR006917///SOUL haem-binding protein+++IPR011256///Regulatory factor, effector binding domain superfamily","[HEBP1_HUMAN|Reviewed]RecName: Full=Heme-binding protein 1; AltName: Full=p22HBP;+++[A0A024RAS8_HUMAN|Unreviewed]SubName: Full=Heme binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW96296.1};+++[F5GWX2_HUMAN|Unreviewed]SubName: Full=Heme-binding protein 1 {ECO:0000313|Ensembl:ENSP00000441678};+++[H0YG71_HUMAN|Unreviewed]SubName: Full=Heme-binding protein 1 {ECO:0000313|Ensembl:ENSP00000442020}; Flags: Fragment;"]
[5096,"'PCCB'",297,287,292,"01100///Metabolic pathways+++00630///Glyoxylate and dicarboxylate metabolism+++00280///Valine, leucine and isoleucine degradation+++00640///Propanoate metabolism+++01130///Biosynthesis of antibiotics+++01200///Carbon metabolism+++01120///Microbial metabolism in diverse environments","H01400///Secondary hyperammonemia+++H00175///Propionic acidemia","M00373///Ethylmalonyl pathway+++M00741///Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA","R01859///propanoyl-CoA:carbon-dioxide ligase (ADP-forming)   ATP + Propanoyl-CoA + HCO3- <=> ADP + Orthophosphate + (S)-Methylmalonyl-CoA","GO:0005759///mitochondrial matrix+++GO:0009317///acetyl-CoA carboxylase complex+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0004658///propionyl-CoA carboxylase activity+++GO:0016874///ligase activity+++GO:0005515///protein binding+++GO:0003989///acetyl-CoA carboxylase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006633///fatty acid biosynthetic process+++GO:0006768///biotin metabolic process","IPR034733///Acetyl-CoA carboxylase+++IPR029045///ClpP/crotonase-like domain superfamily+++IPR011762///Acetyl-coenzyme A carboxyltransferase, N-terminal+++IPR011763///Acetyl-coenzyme A carboxyltransferase, C-terminal","[PCCB_HUMAN|Reviewed]RecName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial; Short=PCCase subunit beta; EC=6.4.1.3; AltName: Full=Propanoyl-CoA:carbon dioxide ligase subunit beta; Flags: Precursor;+++[A0A1B2JLU8_HUMAN|Unreviewed]SubName: Full=PCCB {ECO:0000313|EMBL:ANZ79615.1};+++[C9JAW3_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000418020}; Flags: Fragment;+++[C9JQS9_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000420158};+++[C9JVW9_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000419293}; Flags: Fragment;+++[C9JVY9_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000419263}; Flags: Fragment;+++[E7ENC1_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000420759};+++[E7ETT1_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000420639};+++[E7ETT4_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000418307};+++[E7EUY3_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000420391};+++[E7EX59_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000419129};+++[E9PDR0_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000417549};+++[E9PEC3_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000417253};+++[F8WBI9_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000417937};+++[H7C5C9_HUMAN|Unreviewed]SubName: Full=Propionyl-CoA carboxylase beta chain, mitochondrial {ECO:0000313|Ensembl:ENSP00000419563}; Flags: Fragment;+++[Q9HBR7_HUMAN|Unreviewed]SubName: Full=Propionyl Coenzyme A carboxylase, beta polypeptide, isoform CRA_a {ECO:0000313|EMBL:EAW79116.1};"]
[51009,"'DERL2'",299,310,304.5,"04141///Protein processing in endoplasmic reticulum",null,"M00403///HRD1/SEL1 ERAD complex",null,"GO:0016020///membrane+++GO:0044322///endoplasmic reticulum quality control compartment+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005770///late endosome+++GO:0016021///integral component of membrane+++GO:0048500///signal recognition particle+++GO:0005783///endoplasmic reticulum+++GO:0005785///signal recognition particle receptor complex+++GO:0005769///early endosome+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding","GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0001967///suckling behavior+++GO:0030307///positive regulation of cell growth+++GO:1904380///endoplasmic reticulum mannose trimming+++GO:0006986///response to unfolded protein+++GO:1904153///negative regulation of retrograde protein transport, ER to cytosol+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0030970///retrograde protein transport, ER to cytosol","IPR007599///Derlin","[DERL2_HUMAN|Reviewed]RecName: Full=Derlin-2 {ECO:0000303|PubMed:15215855}; AltName: Full=Degradation in endoplasmic reticulum protein 2; Short=DERtrin-2; AltName: Full=Der1-like protein 2 {ECO:0000303|PubMed:15215855}; AltName: Full=F-LAN-1 {ECO:0000312|EMBL:AAG43049.1}; AltName: Full=F-LANa {ECO:0000303|PubMed:11500051};+++[I3L0R8_HUMAN|Unreviewed]RecName: Full=Derlin {ECO:0000256|RuleBase:RU363059}; Flags: Fragment;+++[I3L1S8_HUMAN|Unreviewed]RecName: Full=Derlin {ECO:0000256|RuleBase:RU363059};+++[I3L1T3_HUMAN|Unreviewed]RecName: Full=Derlin {ECO:0000256|RuleBase:RU363059}; Flags: Fragment;+++[I3L1W3_HUMAN|Unreviewed]RecName: Full=Derlin {ECO:0000256|RuleBase:RU363059};+++[I3L3R8_HUMAN|Unreviewed]SubName: Full=Derlin-2 {ECO:0000313|Ensembl:ENSP00000460671};+++[I3L4W7_HUMAN|Unreviewed]SubName: Full=Derlin-2 {ECO:0000313|Ensembl:ENSP00000461603}; Flags: Fragment;+++[K7EQE8_HUMAN|Unreviewed]SubName: Full=Derlin-2 {ECO:0000313|Ensembl:ENSP00000467794}; Flags: Fragment;"]
[51025,"'PAM16'",148.86,74.92,111.89,null,"H01830///Spondylometaphyseal dysplasia, Megarbane-Dagher-Melki type (SMDMDM)",null,null,"GO:0001405///PAM complex, Tim23 associated import motor+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005744///TIM23 mitochondrial import inner membrane translocase complex+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0031314///extrinsic component of mitochondrial inner membrane","GO:0005515///protein binding","GO:0030150///protein import into mitochondrial matrix+++GO:0001503///ossification+++GO:0015031///protein transport+++GO:0043066///negative regulation of apoptotic process+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0032780///negative regulation of ATPase activity+++GO:1902511///negative regulation of apoptotic DNA fragmentation","IPR005341///Mitochondrial import inner membrane translocase subunit Tim16+++IPR036869///Chaperone J-domain superfamily","[TIM16_HUMAN|Reviewed]RecName: Full=Mitochondrial import inner membrane translocase subunit TIM16; AltName: Full=Mitochondria-associated granulocyte macrophage CSF-signaling molecule; AltName: Full=Presequence translocated-associated motor subunit PAM16;+++[A0A0B4J298_HUMAN|Unreviewed]SubName: Full=HCG15164, isoform CRA_a {ECO:0000313|EMBL:EAW85312.1}; SubName: Full=Mitochondrial import inner membrane translocase subunit TIM16 {ECO:0000313|Ensembl:ENSP00000459802};+++[I3L0X9_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM16 {ECO:0000313|Ensembl:ENSP00000458412};+++[I3L1K9_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM16 {ECO:0000313|Ensembl:ENSP00000458914};+++[I3L1U7_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM16 {ECO:0000313|Ensembl:ENSP00000459113};+++[I3L3G8_HUMAN|Unreviewed]SubName: Full=Mitochondrial import inner membrane translocase subunit TIM16 {ECO:0000313|Ensembl:ENSP00000460434}; Flags: Fragment;+++[I3L3T0_HUMAN|Unreviewed]SubName: Full=HCG15164, isoform CRA_b {ECO:0000313|EMBL:EAW85313.1}; SubName: Full=Mitochondrial import inner membrane translocase subunit TIM16 {ECO:0000313|Ensembl:ENSP00000460708};"]
[5106,"'PCK2'",179,209,194,"04931///Insulin resistance+++01130///Biosynthesis of antibiotics+++04151///PI3K-Akt signaling pathway+++04068///FoxO signaling pathway+++00020///Citrate cycle (TCA cycle)+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++01100///Metabolic pathways+++00010///Glycolysis / Gluconeogenesis+++00620///Pyruvate metabolism+++03320///PPAR signaling pathway+++01120///Microbial metabolism in diverse environments+++04152///AMPK signaling pathway+++04920///Adipocytokine signaling pathway+++04964///Proximal tubule bicarbonate reclamation+++01110///Biosynthesis of secondary metabolites",null,"M00003///Gluconeogenesis, oxaloacetate => fructose-6P","R00431///GTP:oxaloacetate carboxy-lyase (adding GTP;phosphoenolpyruvate-forming); GTP:oxaloacetate   GTP + Oxaloacetate <=> GDP + Phosphoenolpyruvate + CO2+++R00726///ITP:oxaloacetate carboxy-lyase (adding ITP; phosphoenolpyruvate-forming); ITP:oxaloacetate   ITP + Oxaloacetate <=> IDP + Phosphoenolpyruvate + CO2","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol","GO:0004613///phosphoenolpyruvate carboxykinase (GTP) activity+++GO:0005525///GTP binding+++GO:0016301///kinase activity+++GO:0030145///manganese ion binding+++GO:0016831///carboxy-lyase activity+++GO:0000166///nucleotide binding+++GO:0004611///phosphoenolpyruvate carboxykinase activity+++GO:0016829///lyase activity+++GO:0005515///protein binding+++GO:0017076///purine nucleotide binding+++GO:0046872///metal ion binding","GO:0006094///gluconeogenesis+++GO:0006090///pyruvate metabolic process+++GO:0032869///cellular response to insulin stimulus+++GO:0046327///glycerol biosynthetic process from pyruvate+++GO:0071333///cellular response to glucose stimulus+++GO:0042594///response to starvation+++GO:0019543///propionate catabolic process+++GO:0016310///phosphorylation+++GO:0070365///hepatocyte differentiation+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0033993///response to lipid","IPR008209///Phosphoenolpyruvate carboxykinase, GTP-utilising+++IPR013035///Phosphoenolpyruvate carboxykinase, C-terminal+++IPR035077///Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal+++IPR035078///Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal+++IPR008210///Phosphoenolpyruvate carboxykinase, N-terminal+++IPR018091///Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site","[PCKGM_HUMAN|Reviewed]RecName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Short=PEPCK-M; EC=4.1.1.32; Flags: Precursor;+++[A0A0A0MS74_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000380171};+++[A0A0S2Z430_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase 2 isoform 1 {ECO:0000313|EMBL:ALQ33701.1}; Flags: Fragment;+++[A0A0S2Z451_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase 2 isoform 2 {ECO:0000313|EMBL:ALQ33702.1};+++[A0A0S2Z4C0_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase 2 isoform 3 {ECO:0000313|EMBL:ALQ33703.1}; Flags: Fragment;+++[H0YKC4_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000452748};+++[H0YM31_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000453444};+++[H0YMA5_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000453528}; Flags: Fragment;+++[H0YML5_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000453656};+++[H0YMU6_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000453751}; Flags: Fragment;+++[H0YMY3_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000453791}; Flags: Fragment;+++[H0YNG4_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000453998}; Flags: Fragment;+++[H0YNH9_HUMAN|Unreviewed]SubName: Full=Phosphoenolpyruvate carboxykinase [GTP], mitochondrial {ECO:0000313|Ensembl:ENSP00000454020};+++[Q6IB91_HUMAN|Unreviewed]SubName: Full=PCK2 protein {ECO:0000313|EMBL:CAG33194.1};"]
[51075,"'TMX2'",1254,1015,1134.5,{"$nulls":4},"GO:0005575///cellular_component+++GO:0016021///integral component of membrane+++GO:0005623///cell+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process+++GO:0045454///cell redox homeostasis","IPR036249///Thioredoxin-like superfamily+++IPR039101///Thioredoxin-related transmembrane protein 2+++IPR013766///Thioredoxin domain+++IPR037463///Thioredoxin-related transmembrane protein 2, thioredoxin domain","[TMX2_HUMAN|Reviewed]RecName: Full=Thioredoxin-related transmembrane protein 2; AltName: Full=Cell proliferation-inducing gene 26 protein; AltName: Full=Thioredoxin domain-containing protein 14; Flags: Precursor;+++[E9PLR1_HUMAN|Unreviewed]SubName: Full=Thioredoxin-related transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000431333};+++[E9PRL5_HUMAN|Unreviewed]SubName: Full=Thioredoxin-related transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000436013};+++[E9PSF0_HUMAN|Unreviewed]SubName: Full=Thioredoxin-related transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000434002};+++[G3V155_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain containing 14, isoform CRA_a {ECO:0000313|EMBL:EAW73777.1}; SubName: Full=Thioredoxin-related transmembrane protein 2 {ECO:0000313|Ensembl:ENSP00000431695};"]
[51093,"'RRNAD1'",122,101,111.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0008649///rRNA methyltransferase activity+++GO:0000179///rRNA (adenine-N6,N6-)-dimethyltransferase activity","GO:0031167///rRNA methylation+++GO:0032259///methylation+++GO:0000154///rRNA modification","IPR020596///Ribosomal RNA adenine methylase transferase, conserved site+++IPR025714///Methyltransferase domain+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[RRNAD_HUMAN|Reviewed]RecName: Full=Protein RRNAD1; AltName: Full=Ribosomal RNA adenine dimethylase domain-containing protein 1;+++[E5RHI7_HUMAN|Unreviewed]SubName: Full=Protein RRNAD1 {ECO:0000313|Ensembl:ENSP00000429756}; Flags: Fragment;+++[E5RI42_HUMAN|Unreviewed]SubName: Full=Protein RRNAD1 {ECO:0000313|Ensembl:ENSP00000430787};+++[E5RIL6_HUMAN|Unreviewed]SubName: Full=Protein RRNAD1 {ECO:0000313|Ensembl:ENSP00000429389};+++[E5RJL6_HUMAN|Unreviewed]SubName: Full=Protein RRNAD1 {ECO:0000313|Ensembl:ENSP00000429053}; Flags: Fragment;+++[H0YBL9_HUMAN|Unreviewed]SubName: Full=Protein RRNAD1 {ECO:0000313|Ensembl:ENSP00000429800}; Flags: Fragment;"]
[51107,"'APH1A'",1354,1254,1304,"04330///Notch signaling pathway+++05010///Alzheimer's disease",null,"M00682///Notch signaling",null,"GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane+++GO:0032580///Golgi cisterna membrane+++GO:0070765///gamma-secretase complex+++GO:0005886///plasma membrane+++GO:0010008///endosome membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0099056///integral component of presynaptic membrane","GO:0004175///endopeptidase activity+++GO:0005515///protein binding","GO:0042982///amyloid precursor protein metabolic process+++GO:0035333///Notch receptor processing, ligand-dependent+++GO:0007219///Notch signaling pathway+++GO:0016485///protein processing+++GO:0042987///amyloid precursor protein catabolic process+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0006509///membrane protein ectodomain proteolysis+++GO:0034205///amyloid-beta formation+++GO:0043085///positive regulation of catalytic activity+++GO:0001656///metanephros development+++GO:0007220///Notch receptor processing","IPR009294///Gamma-secretase subunit Aph-1","[APH1A_HUMAN|Reviewed]RecName: Full=Gamma-secretase subunit APH-1A; Short=APH-1a; AltName: Full=Aph-1alpha; AltName: Full=Presenilin-stabilization factor;+++[B4DUG7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60161, moderately similar to Gamma-secretase subunit APH-1A {ECO:0000313|EMBL:BAG62329.1};+++[Q5TB21_HUMAN|Unreviewed]SubName: Full=Anterior pharynx defective 1 homolog A (C. elegans) {ECO:0000313|EMBL:CAI22813.1}; SubName: Full=Gamma-secretase subunit APH-1A {ECO:0000313|Ensembl:ENSP00000236017}; Flags: Fragment;"]
[51124,"'IER3IP1'",252,226,239,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030173///integral component of Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0030134///COPII-coated ER to Golgi transport vesicle+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum",null,"GO:2000269///regulation of fibroblast apoptotic process+++GO:0006888///ER to Golgi vesicle-mediated transport","IPR013880///Yos1-like","[IR3IP_HUMAN|Reviewed]RecName: Full=Immediate early response 3-interacting protein 1;+++[A0A1W2PNR9_HUMAN|Unreviewed]SubName: Full=Immediate early response 3-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000491049};"]
[51142,"'CHCHD2'",2042,1270,1656,{"$nulls":4},"GO:0005758///mitochondrial intermembrane space+++GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding","GO:1900037///regulation of cellular response to hypoxia+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007005///mitochondrion organization","IPR010625///CHCH","[CHCH2_HUMAN|Reviewed]RecName: Full=Coiled-coil-helix-coiled-coil-helix domain-containing protein 2; AltName: Full=Aging-associated gene 10 protein; AltName: Full=HCV NS2 trans-regulated protein; Short=NS2TP;"]
[51162,"'EGFL7'",603,430,516.5,"04975///Fat digestion and absorption+++00564///Glycerophospholipid metabolism+++01110///Biosynthesis of secondary metabolites+++00561///Glycerolipid metabolism+++04072///Phospholipase D signaling pathway+++01100///Metabolic pathways","H00419///Congenital generalized lipodystrophy (CGL)","M00089///Triacylglycerol biosynthesis","R02241///acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase Phosphatidate + CoA <=> 1-Acyl-sn-glycerol 3-phosphate + Acyl-CoA+++R09381///acyl-ACP:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase Acyl-[acyl-carrier protein] + 1-Acyl-sn-glycerol 3-phosphate <=> Acyl-carrier protein + Phosphatidate","GO:0043231///intracellular membrane-bounded organelle+++GO:0030054///cell junction+++GO:0005576///extracellular region+++GO:0005764///lysosome+++GO:0035580///specific granule lumen+++GO:0031410///cytoplasmic vesicle+++GO:0005765///lysosomal membrane+++GO:0062023///collagen-containing extracellular matrix+++GO:0005615///extracellular space+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0043202///lysosomal lumen+++GO:0005737///cytoplasm","GO:0005509///calcium ion binding+++GO:0005102///signaling receptor binding+++GO:0016787///hydrolase activity+++GO:0004308///exo-alpha-sialidase activity+++GO:0052796///exo-alpha-(2->8)-sialidase activity+++GO:0005515///protein binding+++GO:0016798///hydrolase activity, acting on glycosyl bonds+++GO:0052794///exo-alpha-(2->3)-sialidase activity+++GO:0016997///alpha-sialidase activity+++GO:0052795///exo-alpha-(2->6)-sialidase activity","GO:0007275///multicellular organism development+++GO:0043312///neutrophil degranulation+++GO:0009313///oligosaccharide catabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0001525///angiogenesis+++GO:0048856///anatomical structure development+++GO:0045746///negative regulation of Notch signaling pathway+++GO:0030154///cell differentiation+++GO:0007155///cell adhesion+++GO:0001568///blood vessel development+++GO:0006687///glycosphingolipid metabolic process+++GO:0001570///vasculogenesis+++GO:0008152///metabolic process+++GO:0006689///ganglioside catabolic process+++GO:0016042///lipid catabolic process+++GO:0006629///lipid metabolic process","IPR000742///EGF-like domain+++IPR013032///EGF-like, conserved site+++IPR001881///EGF-like calcium-binding domain+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR011489///EMI domain+++IPR018097///EGF-like calcium-binding, conserved site+++IPR013111///EGF-like domain, extracellular","[EGFL7_HUMAN|Reviewed]RecName: Full=Epidermal growth factor-like protein 7; Short=EGF-like protein 7; AltName: Full=Multiple epidermal growth factor-like domains protein 7; Short=Multiple EGF-like domains protein 7; AltName: Full=NOTCH4-like protein; AltName: Full=Vascular endothelial statin; Short=VE-statin; AltName: Full=Zneu1; Flags: Precursor;+++[A0A024R8F5_HUMAN|Unreviewed]SubName: Full=EGF-like-domain, multiple 7, isoform CRA_b {ECO:0000313|EMBL:EAW88248.1};+++[A0A024R8H0_HUMAN|Unreviewed]SubName: Full=EGF-like-domain, multiple 7, isoform CRA_a {ECO:0000313|EMBL:EAW88246.1}; Flags: Fragment;+++[A0A0G2JKS5_HUMAN|Unreviewed]SubName: Full=Sialidase-1 {ECO:0000313|Ensembl:ENSP00000435814};+++[E9PIF4_HUMAN|Unreviewed]SubName: Full=Sialidase-1 {ECO:0000313|Ensembl:ENSP00000433127};+++[Q6IBT5_HUMAN|Unreviewed]SubName: Full=NEU1 protein {ECO:0000313|EMBL:CAG32998.1};+++[Q6Q4G7_HUMAN|Unreviewed]SubName: Full=Neurominidase {ECO:0000313|EMBL:AAT11277.1}; Flags: Fragment;+++[Q6Q4G8_HUMAN|Unreviewed]SubName: Full=Neurominidase {ECO:0000313|EMBL:AAT11276.1}; Flags: Fragment;+++[Q6Q4G9_HUMAN|Unreviewed]SubName: Full=Neuraminidase {ECO:0000313|EMBL:AAT11275.1}; Flags: Fragment;+++[R4GMT3_HUMAN|Unreviewed]SubName: Full=Epidermal growth factor-like protein 7 {ECO:0000313|Ensembl:ENSP00000473338}; Flags: Fragment;"]
[51184,"'GPN3'",58,53,55.5,{"$nulls":4},"GO:0032991///protein-containing complex","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003924///GTPase activity",null,"IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR030228///GPN-loop GTPase 3+++IPR004130///GPN-loop GTPase","[GPN3_HUMAN|Reviewed]RecName: Full=GPN-loop GTPase 3 {ECO:0000303|Ref.2}; AltName: Full=ATP-binding domain 1 family member C;+++[F8W1F4_HUMAN|Unreviewed]SubName: Full=GPN-loop GTPase 3 {ECO:0000313|Ensembl:ENSP00000447480}; Flags: Fragment;+++[H0YHZ5_HUMAN|Unreviewed]SubName: Full=GPN-loop GTPase 3 {ECO:0000313|Ensembl:ENSP00000448159}; Flags: Fragment;+++[H0YI19_HUMAN|Unreviewed]SubName: Full=GPN-loop GTPase 3 {ECO:0000313|Ensembl:ENSP00000448335}; Flags: Fragment;+++[S4R3M7_HUMAN|Unreviewed]SubName: Full=GPN-loop GTPase 3 {ECO:0000313|Ensembl:ENSP00000474521}; Flags: Fragment;"]
[51202,"'DDX47'",741,567,654,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004386///helicase activity+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003676///nucleic acid binding","GO:0006915///apoptotic process+++GO:0006364///rRNA processing+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0016070///RNA metabolic process","IPR014014///RNA helicase, DEAD-box type, Q motif+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR000629///ATP-dependent RNA helicase DEAD-box, conserved site+++IPR011545///DEAD/DEAH box helicase domain+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR001650///Helicase, C-terminal","[DDX47_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX47; EC=3.6.4.13; AltName: Full=DEAD box protein 47;+++[A0A024RAS3_HUMAN|Unreviewed]SubName: Full=HCG27698, isoform CRA_a {ECO:0000313|EMBL:EAW96281.1};+++[F5H1N9_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX47 {ECO:0000313|Ensembl:ENSP00000444000}; Flags: Fragment;+++[Q9H4E3_HUMAN|Unreviewed]SubName: Full=DEAD box protein {ECO:0000313|EMBL:CAC14786.1};"]
[51207,"'DUSP13'",2,0,1,null,"H01994///Lafora disease+++H01601///Anaplastic large-cell lymphoma+++H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H01892///Peripheral T cell lymphoma (PTCL)",null,null,"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0007283///spermatogenesis+++GO:0006470///protein dephosphorylation+++GO:0051321///meiotic cell cycle+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0016311///dephosphorylation","IPR024950///Dual specificity phosphatase+++IPR020405///Atypical dual specificity phosphatase, subfamily A+++IPR020422///Dual specificity protein phosphatase domain+++IPR020417///Atypical dual specificity phosphatase+++IPR000387///Tyrosine specific protein phosphatases domain+++IPR029021///Protein-tyrosine phosphatase-like+++IPR016130///Protein-tyrosine phosphatase, active site+++IPR003595///Protein-tyrosine phosphatase, catalytic+++IPR000340///Dual specificity phosphatase, catalytic domain","[DS13A_HUMAN|Reviewed]RecName: Full=Dual specificity protein phosphatase 13 isoform A; Short=DUSP13A; EC=3.1.3.16; EC=3.1.3.48 {ECO:0000305|PubMed:15252030, ECO:0000305|PubMed:29106959}; AltName: Full=Branching-enzyme interacting DSP; AltName: Full=Muscle-restricted DSP; Short=MDSP;+++[DS13B_HUMAN|Reviewed]RecName: Full=Dual specificity protein phosphatase 13 isoform B; Short=DUSP13B; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase SKRP4; AltName: Full=Testis- and skeletal-muscle-specific DSP;+++[E9PSD4_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 13 isoform B {ECO:0000313|Ensembl:ENSP00000434041};+++[U3KQ82_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 13 isoform B {ECO:0000313|Ensembl:ENSP00000475626};+++[U3KQA1_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 13 isoform B {ECO:0000313|Ensembl:ENSP00000475675};+++[U3KQB7_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 13 isoform B {ECO:0000313|Ensembl:ENSP00000475732}; Flags: Fragment;+++[U3KQG1_HUMAN|Unreviewed]SubName: Full=Dual-specificity protein phosphatase 13 isoform B {ECO:0000313|Ensembl:ENSP00000475851}; Flags: Fragment;"]
[51251,"'NT5C3A'",99,92,95.5,"00240///Pyrimidine metabolism+++00230///Purine metabolism+++01100///Metabolic pathways+++01110///Biosynthesis of secondary metabolites+++00760///Nicotinate and nicotinamide metabolism","H00674///Anemia due to disorders of nucleotide metabolism",null,"R01126///inosine 5'-monophosphate phosphohydrolase   IMP + H2O <=> Inosine + Orthophosphate+++R02719///xanthosine 5'-phosphate phosphohydrolase   Xanthosine 5'-phosphate + H2O <=> Xanthosine + Orthophosphate+++R03346///nicotinate D-ribonucleotide phosphohydrolase   Nicotinate D-ribonucleotide + H2O <=> Nicotinate D-ribonucleoside + Orthophosphate+++R01227///guanosine 5'-monophosphate phosphohydrolase   GMP + H2O <=> Guanosine + Orthophosphate+++R00183///adenosine 5'-monophosphate phosphohydrolase   AMP + H2O <=> Adenosine + Orthophosphate+++R00963///uridine 5'-monophosphate phosphohydrolase   UMP + H2O <=> Uridine + Orthophosphate+++R02323///nicotinamide ribonucleotide phosphohydrolase   Nicotinamide D-ribonucleotide + H2O <=> Nicotinamide-beta-riboside + Orthophosphate+++R01968///2'-deoxyguanosine 5'-monophosphate phosphohydrolase   dGMP + H2O <=> Deoxyguanosine + Orthophosphate+++R02088///2'-deoxyadenosine 5'-monophosphate phosphohydrolase   dAMP + H2O <=> Deoxyadenosine + Orthophosphate+++R01569///thymidylate 5'-phosphohydrolase   dTMP + H2O <=> Thymidine + Orthophosphate+++R02102///2'-deoxyuridine 5'-monophosphate phosphohydrolase   dUMP + H2O <=> Deoxyuridine + Orthophosphate+++R00511///cytidine-5'-monophosphate phosphohydrolase   CMP + H2O <=> Cytidine + Orthophosphate+++R01664///2'-deoxycytidine 5'-monophosphate phosphohydrolase   dCMP + H2O <=> Deoxycytidine + Orthophosphate","GO:0005783///endoplasmic reticulum+++GO:0031090///organelle membrane+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0000215///tRNA 2'-phosphotransferase activity+++GO:0000287///magnesium ion binding+++GO:0008253///5'-nucleotidase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0046085///adenosine metabolic process+++GO:0046135///pyrimidine nucleoside catabolic process+++GO:0006213///pyrimidine nucleoside metabolic process+++GO:0016311///dephosphorylation+++GO:0043248///proteasome assembly+++GO:0009117///nucleotide metabolic process","IPR023214///HAD superfamily+++IPR006434///Pyrimidine 5'-nucleotidase, eukaryotic+++IPR036412///HAD-like superfamily","[5NT3A_HUMAN|Reviewed]RecName: Full=Cytosolic 5'-nucleotidase 3A {ECO:0000305|PubMed:15968458, ECO:0000305|PubMed:24603684}; EC=3.1.3.5 {ECO:0000269|PubMed:15968458, ECO:0000269|PubMed:24603684}; AltName: Full=7-methylguanosine phosphate-specific 5'-nucleotidase {ECO:0000305|PubMed:24603684}; Short=7-methylguanosine nucleotidase; EC=3.1.3.91 {ECO:0000269|PubMed:24603684}; AltName: Full=Cytosolic 5'-nucleotidase 3; AltName: Full=Cytosolic 5'-nucleotidase III; Short=cN-III; AltName: Full=Pyrimidine 5'-nucleotidase 1; Short=P5'N-1; Short=P5N-1; Short=PN-I; AltName: Full=Uridine 5'-monophosphate hydrolase 1; AltName: Full=p36;+++[A0A024RA81_HUMAN|Unreviewed]RecName: Full=5'-nucleotidase {ECO:0000256|RuleBase:RU361276}; EC=3.1.3.5 {ECO:0000256|RuleBase:RU361276};+++[A0A090N7U2_HUMAN|Unreviewed]RecName: Full=5'-nucleotidase {ECO:0000256|RuleBase:RU361276}; EC=3.1.3.5 {ECO:0000256|RuleBase:RU361276};+++[B9A035_HUMAN|Unreviewed]SubName: Full=Cytosolic 5'-nucleotidase 3A {ECO:0000313|Ensembl:ENSP00000387205};+++[C9K084_HUMAN|Unreviewed]SubName: Full=Cytosolic 5'-nucleotidase 3A {ECO:0000313|Ensembl:ENSP00000401161}; Flags: Fragment;+++[F8WDR0_HUMAN|Unreviewed]SubName: Full=Cytosolic 5'-nucleotidase 3A {ECO:0000313|Ensembl:ENSP00000389676};+++[X6RM59_HUMAN|Unreviewed]RecName: Full=5'-nucleotidase {ECO:0000256|RuleBase:RU361276}; EC=3.1.3.5 {ECO:0000256|RuleBase:RU361276};"]
[51271,"'UBAP1'",2318,2260,2289,"04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04140///Autophagy - animal+++04668///TNF signaling pathway+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04137///Mitophagy - animal","H01881///Complex cortical dysplasia with other brain malformations+++H01232///Syndromic multisystem autoimmune disease",null,null,"GO:0005886///plasma membrane+++GO:0000813///ESCRT I complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0010008///endosome membrane+++GO:0005768///endosome","GO:0043130///ubiquitin binding+++GO:0005515///protein binding","GO:0043162///ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway+++GO:0019058///viral life cycle+++GO:0015031///protein transport+++GO:0016197///endosomal transport","IPR015940///Ubiquitin-associated domain+++IPR023340///UMA domain+++IPR009060///UBA-like superfamily+++IPR038870///Ubiquitin-associated protein 1","[UBAP1_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated protein 1; Short=UBAP-1; AltName: Full=Nasopharyngeal carcinoma-associated gene 20 protein;+++[A0A0D9SG79_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 1 {ECO:0000313|Ensembl:ENSP00000487222}; Flags: Fragment;+++[Q9HD88_HUMAN|Unreviewed]SubName: Full=NAG20 {ECO:0000313|EMBL:AAF99585.1}; Flags: Fragment;"]
[5129,"'CDK18'",2152,2711,2431.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005575///cellular_component+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity","GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle+++GO:0006468///protein phosphorylation","IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site","[CDK18_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 18; EC=2.7.11.22; AltName: Full=Cell division protein kinase 18; AltName: Full=PCTAIRE-motif protein kinase 3; AltName: Full=Serine/threonine-protein kinase PCTAIRE-3;+++[A0A024R980_HUMAN|Unreviewed]SubName: Full=PCTAIRE protein kinase 3, isoform CRA_a {ECO:0000313|EMBL:EAW91562.1};+++[A0A024R996_HUMAN|Unreviewed]SubName: Full=PCTAIRE protein kinase 3, isoform CRA_b {ECO:0000313|EMBL:EAW91561.1};+++[A0A0A0MSJ6_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 18 {ECO:0000313|Ensembl:ENSP00000391324}; Flags: Fragment;+++[D6R9B0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 18 {ECO:0000313|Ensembl:ENSP00000397831}; Flags: Fragment;+++[D6R9X1_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 18 {ECO:0000313|Ensembl:ENSP00000422842};+++[D6RA44_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 18 {ECO:0000313|Ensembl:ENSP00000423408}; Flags: Fragment;+++[D6RGH0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 18 {ECO:0000313|Ensembl:ENSP00000426368}; Flags: Fragment;+++[Q59G02_HUMAN|Unreviewed]SubName: Full=PCTAIRE protein kinase 3 isoform b variant {ECO:0000313|EMBL:BAD92544.1}; Flags: Fragment;+++[Q8IWB3_HUMAN|Unreviewed]SubName: Full=PCTK3 protein {ECO:0000313|EMBL:AAH40529.1};+++[Q9BWF9_HUMAN|Unreviewed]SubName: Full=PCTK3 protein {ECO:0000313|EMBL:AAH00281.2}; Flags: Fragment;"]
[51306,"'FAM13B'",332,441,386.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007165///signal transduction","IPR039102///Protein FAM13+++IPR008936///Rho GTPase activation protein+++IPR000198///Rho GTPase-activating protein domain","[FA13B_HUMAN|Reviewed]RecName: Full=Protein FAM13B; AltName: Full=GAP-like protein N61;+++[A0A2X0SG06_HUMAN|Unreviewed]SubName: Full=FAM13B {ECO:0000313|EMBL:SPT35755.1}; Flags: Fragment;+++[D6RAT6_HUMAN|Unreviewed]SubName: Full=Protein FAM13B {ECO:0000313|Ensembl:ENSP00000424785}; Flags: Fragment;+++[D6RBJ3_HUMAN|Unreviewed]SubName: Full=Protein FAM13B {ECO:0000313|Ensembl:ENSP00000422673}; Flags: Fragment;+++[D6RCA0_HUMAN|Unreviewed]SubName: Full=Protein FAM13B {ECO:0000313|Ensembl:ENSP00000422311}; Flags: Fragment;+++[D6RDL7_HUMAN|Unreviewed]SubName: Full=Protein FAM13B {ECO:0000313|Ensembl:ENSP00000425326}; Flags: Fragment;+++[D6RE97_HUMAN|Unreviewed]SubName: Full=Protein FAM13B {ECO:0000313|Ensembl:ENSP00000426863}; Flags: Fragment;"]
[51324,"'SPG21'",546,437.04,491.52,"04144///Endocytosis","H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005768///endosome+++GO:0030140///trans-Golgi network transport vesicle+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0010008///endosome membrane","GO:0005515///protein binding+++GO:0042609///CD4 receptor binding","GO:0050851///antigen receptor-mediated signaling pathway","IPR000073///Alpha/beta hydrolase fold-1+++IPR029058///Alpha/Beta hydrolase fold+++IPR026151///Maspardin","[SPG21_HUMAN|Reviewed]RecName: Full=Maspardin; AltName: Full=Acid cluster protein 33; AltName: Full=Spastic paraplegia 21 autosomal recessive Mast syndrome protein; AltName: Full=Spastic paraplegia 21 protein;+++[A0A024R5Y1_HUMAN|Unreviewed]SubName: Full=Spastic paraplegia 21 (Autosomal recessive, Mast syndrome), isoform CRA_a {ECO:0000313|EMBL:EAW77705.1};+++[H0YKB0_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000452728}; Flags: Fragment;+++[H0YKM6_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000452865};+++[H0YLD7_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000453167}; Flags: Fragment;+++[H0YLT5_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000453333}; Flags: Fragment;+++[H0YLW1_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000453362}; Flags: Fragment;+++[H0YMB7_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000453541}; Flags: Fragment;+++[H0YML6_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000453658}; Flags: Fragment;+++[H3BRR0_HUMAN|Unreviewed]SubName: Full=Maspardin {ECO:0000313|Ensembl:ENSP00000456365};"]
[51348,"'KLRF1'",0,1,0.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0032393///MHC class I receptor activity","GO:0050776///regulation of immune response+++GO:0007166///cell surface receptor signaling pathway","IPR033992///Natural killer cell receptor-like, C-type lectin-like domain+++IPR016187///C-type lectin fold+++IPR016186///C-type lectin-like/link domain superfamily+++IPR001304///C-type lectin-like","[KLRF1_HUMAN|Reviewed]RecName: Full=Killer cell lectin-like receptor subfamily F member 1; Short=Lectin-like receptor F1; AltName: Full=Activating coreceptor NKp80; AltName: Full=C-type lectin domain family 5 member C;+++[A0A0C4DFN7_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily F member 1 {ECO:0000313|Ensembl:ENSP00000279545}; SubName: Full=Killer cell lectin-like receptor subfamily F, member 1, isoform CRA_c {ECO:0000313|EMBL:EAW96126.1};+++[A0A0C4DGY9_HUMAN|Unreviewed]SubName: Full=Killer cell lectin-like receptor subfamily F member 1 {ECO:0000313|Ensembl:ENSP00000483713}; SubName: Full=Killer cell lectin-like receptor subfamily F, member 1, isoform CRA_a {ECO:0000313|EMBL:EAW96124.1};+++[Q4KMZ4_HUMAN|Unreviewed]SubName: Full=KLRF1 protein {ECO:0000313|EMBL:AAH98257.1}; SubName: Full=Killer cell lectin-like receptor subfamily F member 1 {ECO:0000313|Ensembl:ENSP00000484826};+++[Q4KN05_HUMAN|Unreviewed]SubName: Full=KLRF1 protein {ECO:0000313|EMBL:AAH98166.1}; SubName: Full=Killer cell lectin-like receptor subfamily F member 1 {ECO:0000313|Ensembl:ENSP00000445022};+++[Q4KN30_HUMAN|Unreviewed]SubName: Full=KLRF1 protein {ECO:0000313|EMBL:AAH96734.1}; SubName: Full=Killer cell lectin-like receptor subfamily F member 1 {ECO:0000313|Ensembl:ENSP00000443054};"]
[51373,"'MRPS17'",133,106,119.5,"03010///Ribosome",null,"M00178///Ribosome, bacteria+++M00179///Ribosome, archaea",null,"GO:0005739///mitochondrion+++GO:0005840///ribosome+++GO:0005763///mitochondrial small ribosomal subunit+++GO:0005743///mitochondrial inner membrane","GO:0019843///rRNA binding+++GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0070125///mitochondrial translational elongation+++GO:0006412///translation+++GO:0032543///mitochondrial translation+++GO:0070126///mitochondrial translational termination","IPR039193///28S ribosomal protein S17, mitochondrial+++IPR036051///KRAB domain superfamily+++IPR012340///Nucleic acid-binding, OB-fold+++IPR000266///Ribosomal protein S17/S11+++IPR001909///Krueppel-associated box","[RT17_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S17, mitochondrial; Short=MRP-S17; Short=S17mt; AltName: Full=Mitochondrial small ribosomal subunit protein uS17m {ECO:0000303|PubMed:25838379}; Flags: Precursor;+++[E9PE17_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S17, mitochondrial {ECO:0000313|Ensembl:ENSP00000401349}; Flags: Fragment;+++[Q8IY71_HUMAN|Unreviewed]SubName: Full=MRPS17 protein {ECO:0000313|EMBL:AAH37405.1}; Flags: Fragment;+++[Q96Q59_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein S17 {ECO:0000313|EMBL:BAB54942.1}; Flags: Fragment;"]
[51374,"'ATRAID'",1731,1442,1586.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005635///nuclear envelope+++GO:0005765///lysosomal membrane+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0010468///regulation of gene expression+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0030154///cell differentiation+++GO:1903363///negative regulation of cellular protein catabolic process+++GO:0030501///positive regulation of bone mineralization+++GO:0033689///negative regulation of osteoblast proliferation","IPR013032///EGF-like, conserved site+++IPR000742///EGF-like domain","[ARAID_HUMAN|Reviewed]RecName: Full=All-trans retinoic acid-induced differentiation factor; AltName: Full=Apoptosis-related protein 3; Short=APR-3; AltName: Full=p18; Flags: Precursor;+++[C9JA62_HUMAN|Unreviewed]SubName: Full=All-trans retinoic acid-induced differentiation factor {ECO:0000313|Ensembl:ENSP00000397319}; Flags: Fragment;+++[D6W551_HUMAN|Unreviewed]SubName: Full=Chromosome 2 open reading frame 28, isoform CRA_d {ECO:0000313|EMBL:EAX00619.1};"]
[51397,"'COMMD10'",94,78,86,"04137///Mitophagy - animal+++04360///Axon guidance+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0035924///cellular response to vascular endothelial growth factor stimulus+++GO:0032197///transposition, RNA-mediated+++GO:0006915///apoptotic process+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:2001224///positive regulation of neuron migration+++GO:1903671///negative regulation of sprouting angiogenesis+++GO:0007399///nervous system development+++GO:0009887///animal organ morphogenesis+++GO:0006351///transcription, DNA-templated+++GO:0007010///cytoskeleton organization+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:1900747///negative regulation of vascular endothelial growth factor signaling pathway+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0106089///negative regulation of cell adhesion involved in sprouting angiogenesis+++GO:0016525///negative regulation of angiogenesis+++GO:0007411///axon guidance+++GO:0007166///cell surface receptor signaling pathway+++GO:0006310///DNA recombination+++GO:0006355///regulation of transcription, DNA-templated","IPR037361///COMM domain-containing protein 10+++IPR017920///COMM domain","[COMDA_HUMAN|Reviewed]RecName: Full=COMM domain-containing protein 10;+++[D6RC04_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000422448};+++[D6RJ90_HUMAN|Unreviewed]SubName: Full=COMM domain containing 10, isoform CRA_b {ECO:0000313|EMBL:EAW48943.1}; SubName: Full=COMM domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000427319};+++[H0Y9N4_HUMAN|Unreviewed]SubName: Full=COMM domain-containing protein 10 {ECO:0000313|Ensembl:ENSP00000424611}; Flags: Fragment;+++[L8EAU8_HUMAN|Unreviewed]SubName: Full=Alternative protein COMMD10 {ECO:0000313|EMBL:CCQ43533.1};"]
[51429,"'SNX9'",638,627,632.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030659///cytoplasmic vesicle membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005623///cell+++GO:0001726///ruffle+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0030136///clathrin-coated vesicle+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network","GO:0031625///ubiquitin protein ligase binding+++GO:0035091///phosphatidylinositol binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0042803///protein homodimerization activity+++GO:0008289///lipid binding+++GO:0042802///identical protein binding+++GO:0071933///Arp2/3 complex binding","GO:0032461///positive regulation of protein oligomerization+++GO:0043547///positive regulation of GTPase activity+++GO:0045860///positive regulation of protein kinase activity+++GO:0000278///mitotic cell cycle+++GO:0006886///intracellular protein transport+++GO:0036089///cleavage furrow formation+++GO:0006897///endocytosis+++GO:0016197///endosomal transport+++GO:0000281///mitotic cytokinesis+++GO:0051301///cell division+++GO:0051044///positive regulation of membrane protein ectodomain proteolysis+++GO:0006898///receptor-mediated endocytosis+++GO:0007049///cell cycle+++GO:0060988///lipid tube assembly+++GO:0015031///protein transport+++GO:0097320///plasma membrane tubulation+++GO:0061024///membrane organization","IPR027267///AH/BAR domain superfamily+++IPR028644///Sorting nexin-9+++IPR036028///SH3-like domain superfamily+++IPR037425///Sorting nexin-9, BAR domain+++IPR039358///Sorting nexin-like+++IPR037426///Sorting nexin-9, PX domain+++IPR036871///PX domain superfamily+++IPR001452///SH3 domain+++IPR014536///Sorting nexin 9 family+++IPR019497///Sorting nexin protein, WASP-binding domain+++IPR001683///Phox homologous domain+++IPR035558///SNX9, SH3 domain","[SNX9_HUMAN|Reviewed]RecName: Full=Sorting nexin-9; AltName: Full=SH3 and PX domain-containing protein 1; Short=Protein SDP1; AltName: Full=SH3 and PX domain-containing protein 3A;+++[A0A087WVE4_HUMAN|Unreviewed]SubName: Full=Sorting nexin-9 {ECO:0000313|Ensembl:ENSP00000479382}; Flags: Fragment;+++[A0A087WZW2_HUMAN|Unreviewed]SubName: Full=Sorting nexin-9 {ECO:0000313|Ensembl:ENSP00000482920}; Flags: Fragment;+++[O95061_HUMAN|Unreviewed]SubName: Full=WASP interactor protein {ECO:0000313|EMBL:AAD00898.2}; Flags: Fragment;"]
[51454,"'GULP1'",354,460,407,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0042803///protein homodimerization activity","GO:0006909///phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0006869///lipid transport+++GO:0006915///apoptotic process","IPR011993///PH-like domain superfamily+++IPR006020///PTB/PI domain","[GULP1_HUMAN|Reviewed]RecName: Full=PTB domain-containing engulfment adapter protein 1; AltName: Full=Cell death protein 6 homolog; AltName: Full=PTB domain adapter protein CED-6; AltName: Full=Protein GULP;+++[B8ZZL1_HUMAN|Unreviewed]SubName: Full=PTB domain-containing engulfment adapter protein 1 {ECO:0000313|Ensembl:ENSP00000386809}; Flags: Fragment;+++[H0Y6R1_HUMAN|Unreviewed]SubName: Full=PTB domain-containing engulfment adapter protein 1 {ECO:0000313|Ensembl:ENSP00000407131}; Flags: Fragment;+++[H7BZV7_HUMAN|Unreviewed]SubName: Full=PTB domain-containing engulfment adapter protein 1 {ECO:0000313|Ensembl:ENSP00000391712}; Flags: Fragment;"]
[51490,"'SPOUT1'",407,354,380.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0000777///condensed chromosome kinetochore+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0005815///microtubule organizing center+++GO:0005819///spindle+++GO:0000776///kinetochore+++GO:0031616///spindle pole centrosome+++GO:0005856///cytoskeleton+++GO:0072686///mitotic spindle","GO:0005515///protein binding+++GO:0035198///miRNA binding+++GO:0003723///RNA binding+++GO:0016740///transferase activity+++GO:0008168///methyltransferase activity","GO:0051301///cell division+++GO:0007049///cell cycle+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0032259///methylation+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0051661///maintenance of centrosome location","IPR029026///tRNA (guanine-N1-)-methyltransferase, N-terminal+++IPR003750///Putative RNA methyltransferase+++IPR029028///Alpha/beta knot methyltransferases+++IPR012340///Nucleic acid-binding, OB-fold","[CI114_HUMAN|Reviewed]RecName: Full=Putative methyltransferase C9orf114 {ECO:0000305}; EC=2.1.1.- {ECO:0000305}; AltName: Full=Centromere protein 32 {ECO:0000303|PubMed:25657325}; Short=CENP-32 {ECO:0000303|PubMed:25657325}; AltName: Full=Kinetochore-associated protein {ECO:0000303|PubMed:20813266}; AltName: Full=SPOUT domain-containing methyltransferase 1 {ECO:0000312|HGNC:HGNC:26933};+++[R4GNG4_HUMAN|Unreviewed]SubName: Full=Putative methyltransferase C9orf114 {ECO:0000313|Ensembl:ENSP00000473640}; Flags: Fragment;"]
[51510,"'CHMP5'",875,491,683,"04144///Endocytosis+++04217///Necroptosis",null,"M00412///ESCRT-III complex",null,"GO:0005737///cytoplasm+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0010008///endosome membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0036258///multivesicular body assembly+++GO:0071222///cellular response to lipopolysaccharide+++GO:0071985///multivesicular body sorting pathway+++GO:0007034///vacuolar transport+++GO:0007080///mitotic metaphase plate congression+++GO:0010824///regulation of centrosome duplication+++GO:0071225///cellular response to muramyl dipeptide+++GO:0006997///nucleus organization+++GO:1901673///regulation of mitotic spindle assembly+++GO:0019058///viral life cycle+++GO:0001919///regulation of receptor recycling+++GO:0061952///midbody abscission+++GO:0015031///protein transport+++GO:0007040///lysosome organization+++GO:0008333///endosome to lysosome transport+++GO:1904903///ESCRT III complex disassembly","IPR005024///Snf7 family","[CHMP5_HUMAN|Reviewed]RecName: Full=Charged multivesicular body protein 5; AltName: Full=Chromatin-modifying protein 5; AltName: Full=SNF7 domain-containing protein 2; AltName: Full=Vacuolar protein sorting-associated protein 60; Short=Vps60; Short=hVps60;"]
[51531,"'TRMO'",125,97,111,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0016740///transferase activity+++GO:0016430///tRNA (adenine-N6-)-methyltransferase activity+++GO:0008168///methyltransferase activity","GO:0008033///tRNA processing+++GO:0030488///tRNA methylation+++GO:0032259///methylation","IPR036413///YaeB-like superfamily+++IPR036414///YaeB, N-terminal domain superfamily+++IPR023370///YaeB-like, N-terminal domain+++IPR023368///Uncharacterised protein family UPF0066, conserved site","[TRMO_HUMAN|Reviewed]RecName: Full=tRNA (adenine(37)-N6)-methyltransferase {ECO:0000305}; EC=2.1.1.- {ECO:0000269|PubMed:25063302}; AltName: Full=tRNA methyltransferase O {ECO:0000303|PubMed:25063302, ECO:0000312|HGNC:HGNC:30967};+++[Q5T111_HUMAN|Unreviewed]SubName: Full=tRNA (adenine(37)-N6)-methyltransferase {ECO:0000313|Ensembl:ENSP00000408473}; Flags: Fragment;+++[Q5T112_HUMAN|Unreviewed]SubName: Full=tRNA (adenine(37)-N6)-methyltransferase {ECO:0000313|Ensembl:ENSP00000364258}; Flags: Fragment;+++[Q5T114_HUMAN|Unreviewed]SubName: Full=Chromosome 9 open reading frame 156, isoform CRA_b {ECO:0000313|EMBL:EAW58859.1}; SubName: Full=tRNA (adenine(37)-N6)-methyltransferase {ECO:0000313|Ensembl:ENSP00000364259};+++[Q6Y2L2_HUMAN|Unreviewed]SubName: Full=LP4790 protein {ECO:0000313|EMBL:AAO86724.1}; SubName: Full=tRNA (adenine(37)-N6)-methyltransferase {ECO:0000313|Ensembl:ENSP00000483071};"]
[51554,"'ACKR4'",2,0,1,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0009986///cell surface+++GO:0005769///early endosome+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005768///endosome+++GO:0055037///recycling endosome+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0005887///integral component of plasma membrane","GO:0019957///C-C chemokine binding+++GO:0004930///G protein-coupled receptor activity+++GO:0019956///chemokine binding+++GO:0004950///chemokine receptor activity+++GO:0005044///scavenger receptor activity+++GO:0005515///protein binding+++GO:0016493///C-C chemokine receptor activity","GO:0006935///chemotaxis+++GO:0060326///cell chemotaxis+++GO:0006898///receptor-mediated endocytosis+++GO:0007165///signal transduction+++GO:0007204///positive regulation of cytosolic calcium ion concentration+++GO:0006954///inflammatory response+++GO:0070098///chemokine-mediated signaling pathway+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0019722///calcium-mediated signaling+++GO:0006955///immune response","IPR000355///Chemokine receptor family+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR005383///Atypical chemokine receptor 4+++IPR017452///GPCR, rhodopsin-like, 7TM","[ACKR4_HUMAN|Reviewed]RecName: Full=Atypical chemokine receptor 4; AltName: Full=C-C chemokine receptor type 11; Short=C-C CKR-11; Short=CC-CKR-11; Short=CCR-11; AltName: Full=CC chemokine receptor-like 1; Short=CCRL1; AltName: Full=CCX CKR;+++[H0Y9Z2_HUMAN|Unreviewed]SubName: Full=Atypical chemokine receptor 4 {ECO:0000313|Ensembl:ENSP00000425557}; Flags: Fragment;+++[K7EPC9_HUMAN|Unreviewed]SubName: Full=C-C chemokine receptor type 10 {ECO:0000313|Ensembl:ENSP00000467331}; Flags: Fragment;+++[K7ER70_HUMAN|Unreviewed]SubName: Full=C-C chemokine receptor type 10 {ECO:0000313|Ensembl:ENSP00000468135};+++[Q4VBN4_HUMAN|Unreviewed]SubName: Full=CCRL1 protein {ECO:0000313|EMBL:AAH95501.1}; Flags: Fragment;+++[Q7Z7I1_HUMAN|Unreviewed]SubName: Full=Chemokine receptor D6 {ECO:0000313|EMBL:AAP42156.1};"]
[51575,"'ESF1'",228,178,203,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04714///Thermogenesis","H00473///Mitochondrial complex I deficiency",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005615///extracellular space","GO:0003723///RNA binding","GO:0006364///rRNA processing","IPR039754///Pre-rRNA-processing protein Esf1+++IPR012580///NUC153","[ESF1_HUMAN|Reviewed]RecName: Full=ESF1 homolog; AltName: Full=ABT1-associated protein;+++[A0A087WX71_HUMAN|Unreviewed]SubName: Full=ESF1 homolog {ECO:0000313|Ensembl:ENSP00000480783};+++[A0JLU5_HUMAN|Unreviewed]SubName: Full=ESF1 protein {ECO:0000313|EMBL:AAH20952.1}; Flags: Fragment;+++[Q05C10_HUMAN|Unreviewed]SubName: Full=ESF1 protein {ECO:0000313|EMBL:AAH30513.1}; Flags: Fragment;+++[Q3SWV1_HUMAN|Unreviewed]SubName: Full=ESF1 protein {ECO:0000313|EMBL:AAI04664.1}; Flags: Fragment;+++[Q6P6H6_HUMAN|Unreviewed]SubName: Full=ESF1 protein {ECO:0000313|EMBL:AAH62214.1}; Flags: Fragment;+++[Q8IWH6_HUMAN|Unreviewed]SubName: Full=ESF1 protein {ECO:0000313|EMBL:AAH39706.2}; Flags: Fragment;"]
[51602,"'NOP58'",470,343,406.5,"03008///Ribosome biogenesis in eukaryotes","H01866///Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis+++H01619///Primary pulmonary hypertension (PPH)+++H01621///Pulmonary arterial hypertension (PAH)","M00679///BMP signaling",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0001650///fibrillar center+++GO:0070761///pre-snoRNP complex+++GO:0032040///small-subunit processome+++GO:0015030///Cajal body+++GO:0005730///nucleolus+++GO:0005732///small nucleolar ribonucleoprotein complex+++GO:0016020///membrane+++GO:0031428///box C/D snoRNP complex","GO:0001094///TFIID-class transcription factor complex binding+++GO:0030515///snoRNA binding+++GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0051117///ATPase binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0048254///snoRNA localization","IPR012976///NOSIC+++IPR012974///NOP5, N-terminal+++IPR002687///Nop domain+++IPR029012///Helix hairpin bin domain superfamily+++IPR036070///Nop domain superfamily","[NOP58_HUMAN|Reviewed]RecName: Full=Nucleolar protein 58; AltName: Full=Nucleolar protein 5;+++[F8WED0_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 58 {ECO:0000313|Ensembl:ENSP00000388905};+++[H7BZ72_HUMAN|Unreviewed]SubName: Full=Nucleolar protein 58 {ECO:0000313|Ensembl:ENSP00000388126}; Flags: Fragment;"]
[51629,"'SLC25A39'",3679,3260,3469.5,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane","GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0006783///heme biosynthetic process","IPR040062///Mitochondrial carrier domain protein+++IPR002067///Mitochondrial carrier protein+++IPR018108///Mitochondrial substrate/solute carrier+++IPR023395///Mitochondrial carrier domain superfamily","[S2539_HUMAN|Reviewed]RecName: Full=Solute carrier family 25 member 39;+++[B4DFG5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000444540}; SubName: Full=cDNA FLJ51715, highly similar to Mitochondrial carrier protein CGI-69 {ECO:0000313|EMBL:BAG57426.1};+++[K7EJI2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000465182}; Flags: Fragment;+++[K7EKC2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000465554}; Flags: Fragment;+++[K7EKF4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000465594}; Flags: Fragment;+++[K7ELM7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000466144}; Flags: Fragment;+++[K7EMR4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000466615}; Flags: Fragment;+++[K7EMW3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000466676};+++[K7EQS4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000467956}; Flags: Fragment;+++[K7EQS8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25 member 39 {ECO:0000313|Ensembl:ENSP00000467964}; Flags: Fragment;"]
[51650,"'MRPS33'",145,147,146,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005840///ribosome+++GO:0005763///mitochondrial small ribosomal subunit","GO:0003735///structural constituent of ribosome","GO:0006412///translation+++GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation","IPR013219///Ribosomal protein S27/S33, mitochondrial","[RT33_HUMAN|Reviewed]RecName: Full=28S ribosomal protein S33, mitochondrial; Short=MRP-S33; Short=S33mt; AltName: Full=Mitochondrial small ribosomal subunit protein mS33 {ECO:0000303|PubMed:25838379};+++[A4D1T3_HUMAN|Unreviewed]SubName: Full=Mitochondrial ribosomal protein S33 {ECO:0000313|EMBL:EAL24022.1}; SubName: Full=Mitochondrial ribosomal protein S33, isoform CRA_a {ECO:0000313|EMBL:EAW83966.1};+++[C9JBY7_HUMAN|Unreviewed]SubName: Full=28S ribosomal protein S33, mitochondrial {ECO:0000313|Ensembl:ENSP00000420709};+++[Q3KRB4_HUMAN|Unreviewed]SubName: Full=MRPS33 protein {ECO:0000313|EMBL:AAI05794.1}; Flags: Fragment;"]
[5167,"'ENPP1'",14,14,14,"00770///Pantothenate and CoA biosynthesis+++00740///Riboflavin metabolism+++00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00760///Nicotinate and nicotinamide metabolism+++00500///Starch and sucrose metabolism+++00230///Purine metabolism","H02139///Autosomal recessive hypophosphatemic rickets+++H02106///Genetic obesity+++H00409///Type II diabetes mellitus+++H01394///Cole disease+++H00431///Ossification of the posterior longitudinal ligament of spine (OPLL)+++H00214///Hypophosphatemic rickets+++H01002///Generalized arterial calcification of infancy",null,"R00515///CTP diphosphohydrolase (diphosphate-forming); CTP   CTP + H2O <=> CMP + Diphosphate+++R11323///dTTP diphosphohydrolase   dTTP + H2O <=> dTMP + Diphosphate+++R00087///ATP diphosphohydrolase (diphosphate-forming); ATP   ATP + H2O <=> AMP + Diphosphate+++R00662///Uridine triphosphate pyrophosphohydrolase   UTP + H2O <=> UMP + Diphosphate+++R00287///UDP-glucose glucophosphohydrolase   UDP-glucose + H2O <=> UMP + D-Glucose 1-phosphate+++R00056///dinucleotide nucleotidohydrolase   Dinucleotide + H2O <=> 2 Mononucleotide+++R03036///Dephospho-CoA nucleotidohydrolase   Dephospho-CoA + H2O <=> Pantetheine 4'-phosphate + AMP+++R03004///Deamino-NAD+ nucleotidohydrolase   Deamino-NAD+ + H2O <=> AMP + Nicotinate D-ribonucleotide+++R00160///FAD nucleotidohydrolase   FAD + H2O <=> AMP + FMN+++R00103///NAD+ phosphohydrolase   NAD+ + H2O <=> AMP + Nicotinamide D-ribonucleotide","GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0005765///lysosomal membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0009986///cell surface+++GO:0016323///basolateral plasma membrane+++GO:0005615///extracellular space","GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0005524///ATP binding+++GO:0004527///exonuclease activity+++GO:0047429///nucleoside-triphosphate diphosphatase activity+++GO:0050656///3'-phosphoadenosine 5'-phosphosulfate binding+++GO:0005158///insulin receptor binding+++GO:0042803///protein homodimerization activity+++GO:0016787///hydrolase activity+++GO:0004551///nucleotide diphosphatase activity+++GO:0030247///polysaccharide binding+++GO:0005044///scavenger receptor activity+++GO:0004528///phosphodiesterase I activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0035529///NADH pyrophosphatase activity","GO:0006955///immune response+++GO:0045599///negative regulation of fat cell differentiation+++GO:0030730///sequestering of triglyceride+++GO:0009143///nucleoside triphosphate catabolic process+++GO:0030308///negative regulation of cell growth+++GO:0031214///biomineral tissue development+++GO:0006771///riboflavin metabolic process+++GO:0030643///cellular phosphate ion homeostasis+++GO:0045719///negative regulation of glycogen biosynthetic process+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0031953///negative regulation of protein autophosphorylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process+++GO:0006796///phosphate-containing compound metabolic process+++GO:0046325///negative regulation of glucose import+++GO:0006898///receptor-mediated endocytosis+++GO:0030505///inorganic diphosphate transport+++GO:0032869///cellular response to insulin stimulus+++GO:0046034///ATP metabolic process+++GO:0030500///regulation of bone mineralization+++GO:0006091///generation of precursor metabolites and energy","IPR017850///Alkaline-phosphatase-like, core domain superfamily+++IPR002591///Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase+++IPR017849///Alkaline phosphatase-like, alpha/beta/alpha+++IPR001604///DNA/RNA non-specific endonuclease+++IPR020821///Extracellular Endonuclease, subunit A+++IPR001212///Somatomedin B domain+++IPR036024///Somatomedin B-like domain superfamily+++IPR020436///Somatomedin B, chordata","[ENPP1_HUMAN|Reviewed]RecName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 1; Short=E-NPP 1; AltName: Full=Membrane component chromosome 6 surface marker 1; AltName: Full=Phosphodiesterase I/nucleotide pyrophosphatase 1; AltName: Full=Plasma-cell membrane glycoprotein PC-1; Includes: RecName: Full=Alkaline phosphodiesterase I; EC=3.1.4.1 {ECO:0000269|PubMed:8001561}; Includes: RecName: Full=Nucleotide pyrophosphatase; Short=NPPase; EC=3.6.1.9 {ECO:0000269|PubMed:8001561}; AltName: Full=Nucleotide diphosphatase {ECO:0000305};+++[E9PE72_HUMAN|Unreviewed]SubName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 {ECO:0000313|Ensembl:ENSP00000422424};+++[Q9NS95_HUMAN|Unreviewed]SubName: Full=Phosphodiesterase I/nucleotide pyrophosphatase 1 {ECO:0000313|EMBL:BAA97562.1}; Flags: Fragment;"]
[51701,"'NLK'",291,425,358,"04068///FoxO signaling pathway+++04010///MAPK signaling pathway+++04310///Wnt signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0004672///protein kinase activity+++GO:0000287///magnesium ion binding+++GO:0042169///SH2 domain binding+++GO:0005524///ATP binding+++GO:0004707///MAP kinase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0008134///transcription factor binding","GO:0018107///peptidyl-threonine phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0050821///protein stabilization+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0006468///protein phosphorylation+++GO:0016055///Wnt signaling pathway+++GO:0010468///regulation of gene expression+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0046777///protein autophosphorylation+++GO:0006351///transcription, DNA-templated+++GO:0042501///serine phosphorylation of STAT protein+++GO:0030178///negative regulation of Wnt signaling pathway","IPR003527///Mitogen-activated protein (MAP) kinase, conserved site+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[NLK_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase NLK; EC=2.7.11.24; AltName: Full=Nemo-like kinase; AltName: Full=Protein LAK1;+++[A0A024QZ12_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812};+++[H0YD75_HUMAN|Unreviewed]RecName: Full=Mitogen-activated protein kinase {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812}; EC=2.7.11.24 {ECO:0000256|RuleBase:RU361165, ECO:0000256|SAAS:SAAS00652812}; Flags: Fragment;+++[J3QSE9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase NLK {ECO:0000313|Ensembl:ENSP00000464656};"]
[51728,"'POLR3K'",105,70,87.5,"01100///Metabolic pathways+++04623///Cytosolic DNA-sensing pathway+++05169///Epstein-Barr virus infection+++00240///Pyrimidine metabolism+++03020///RNA polymerase+++00230///Purine metabolism",null,"M00181///RNA polymerase III, eukaryotes","R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA","GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0005654///nucleoplasm","GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0008270///zinc ion binding+++GO:0003676///nucleic acid binding+++GO:0001056///RNA polymerase III activity+++GO:0046872///metal ion binding","GO:0051607///defense response to virus+++GO:0006386///termination of RNA polymerase III transcription+++GO:0002376///immune system process+++GO:0006351///transcription, DNA-templated+++GO:0042779///tRNA 3'-trailer cleavage+++GO:0045087///innate immune response+++GO:0006383///transcription by RNA polymerase III","IPR019761///DNA-directed RNA polymerase M, 15kDa subunit, conserved site+++IPR034014///Pol III subunit C11, C-terminal zinc ribbon+++IPR012164///DNA-directed RNA polymerase subunit/transcription factor S+++IPR001529///DNA-directed RNA polymerase, M/15kDa subunit+++IPR001222///Zinc finger, TFIIS-type","[RPC10_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase III subunit RPC10; Short=RNA polymerase III subunit C10; AltName: Full=DNA-directed RNA polymerase III subunit K; AltName: Full=RNA polymerase III 12.5 kDa subunit; Short=RPC12.5; AltName: Full=RNA polymerase III subunit C11; Short=HsC11p; Short=RPC11; Short=hRPC11;+++[L0R6M6_HUMAN|Unreviewed]SubName: Full=Alternative protein POLR3K {ECO:0000313|EMBL:CCO13792.1};"]
[5176,"'SERPINF1'",933,660,796.5,"04310///Wnt signaling pathway","H00506///Osteogenesis imperfecta",null,null,"GO:0070062///extracellular exosome+++GO:0030424///axon+++GO:0062023///collagen-containing extracellular matrix+++GO:0005604///basement membrane+++GO:0043203///axon hillock+++GO:0048471///perinuclear region of cytoplasm+++GO:0043025///neuronal cell body+++GO:0005615///extracellular space+++GO:0042470///melanosome+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0004867///serine-type endopeptidase inhibitor activity","GO:0042698///ovulation cycle+++GO:0010447///response to acidic pH+++GO:0007568///aging+++GO:0060770///negative regulation of epithelial cell proliferation involved in prostate gland development+++GO:0007614///short-term memory+++GO:0010629///negative regulation of gene expression+++GO:0071279///cellular response to cobalt ion+++GO:0071300///cellular response to retinoic acid+++GO:0071333///cellular response to glucose stimulus+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010976///positive regulation of neuron projection development+++GO:1901215///negative regulation of neuron death+++GO:0050728///negative regulation of inflammatory response+++GO:0007275///multicellular organism development+++GO:0071549///cellular response to dexamethasone stimulus+++GO:0050769///positive regulation of neurogenesis+++GO:0016525///negative regulation of angiogenesis+++GO:0001822///kidney development+++GO:0060041///retina development in camera-type eye+++GO:0010596///negative regulation of endothelial cell migration+++GO:0046685///response to arsenic-containing substance+++GO:0008283///cell proliferation","IPR023796///Serpin domain+++IPR000215///Serpin family+++IPR023795///Serpin, conserved site+++IPR036186///Serpin superfamily+++IPR033832///Pigment epithelium derived factor","[PEDF_HUMAN|Reviewed]RecName: Full=Pigment epithelium-derived factor; Short=PEDF; AltName: Full=Cell proliferation-inducing gene 35 protein; AltName: Full=EPC-1; AltName: Full=Serpin F1; Flags: Precursor;+++[A0A0J9YXF9_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000488386}; Flags: Fragment;+++[A0A0J9YXW2_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000488572}; Flags: Fragment;+++[A0A140VKF3_HUMAN|Unreviewed]SubName: Full=Testis tissue sperm-binding protein Li 70n {ECO:0000313|EMBL:AEE61290.1};+++[I3L107_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000458484}; Flags: Fragment;+++[I3L1U4_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000459107};+++[I3L2R7_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000459869}; Flags: Fragment;+++[I3L3Z3_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000460842}; Flags: Fragment;+++[I3L425_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000460905}; Flags: Fragment;+++[I3L4F9_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000461214}; Flags: Fragment;+++[I3L4N7_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000461405}; Flags: Fragment;+++[I3L4Z0_HUMAN|Unreviewed]SubName: Full=Pigment epithelium-derived factor {ECO:0000313|Ensembl:ENSP00000461660}; Flags: Fragment;"]
[51805,"'COQ3'",23,20,21.5,"00130///Ubiquinone and other terpenoid-quinone biosynthesis+++01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways",null,"M00128///Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone","R04711///S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase   S-Adenosyl-L-methionine + 3-Hexaprenyl-4,5-dihydroxybenzoate <=> S-Adenosyl-L-homocysteine + 3-Hexaprenyl-4-hydroxy-5-methoxybenzoate + H++++R08771///S-adenosyl-L-methionine:3-Polyprenyl-4,5-dihydroxylate 5-O-methyltransferase   3-Polyprenyl-4,5-dihydroxybenzoate + S-Adenosyl-L-methionine <=> 3-Polyprenyl-4-hydroxy-5-methoxybenzoate + S-Adenosyl-L-homocysteine+++R02175///S-adenosyl-L-methionine:2-hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase   2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + S-Adenosyl-L-methionine <=> Ubiquinone-6 + S-Adenosyl-L-homocysteine+++R07235///S-adenosyl-L-methionine:2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone 3-O-methyltransferase   S-Adenosyl-L-methionine + 3-Demethylubiquinone-9 <=> S-Adenosyl-L-homocysteine + Ubiquinone-9+++R08781///S-adenosyl-L-methionine:3-hydroxy-2-methoxy-5-methyl-6-(all-trans-polyprenyl)-1,4-benzoquinone 3-O-methyltransferase   2-Polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + S-Adenosyl-L-methionine <=> Ubiquinone + S-Adenosyl-L-homocysteine","GO:0016020///membrane+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane","GO:0004395///hexaprenyldihydroxybenzoate methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0044596///3-demethylubiquinone-10 3-O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0008171///O-methyltransferase activity+++GO:0005515///protein binding+++GO:0008425///2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity+++GO:0008689///3-demethylubiquinone-9 3-O-methyltransferase activity+++GO:0044595///decaprenyldihydroxybenzoate methyltransferase activity","GO:0006744///ubiquinone biosynthetic process+++GO:0006071///glycerol metabolic process+++GO:0032259///methylation+++GO:0010795///regulation of ubiquinone biosynthetic process","IPR029063///S-adenosyl-L-methionine-dependent methyltransferase+++IPR010233///Ubiquinone biosynthesis O-methyltransferase","[COQ3_HUMAN|Reviewed]RecName: Full=Ubiquinone biosynthesis O-methyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03190}; AltName: Full=3-demethylubiquinol 3-O-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03190}; EC=2.1.1.64 {ECO:0000255|HAMAP-Rule:MF_03190}; AltName: Full=Polyprenyldihydroxybenzoate methyltransferase {ECO:0000255|HAMAP-Rule:MF_03190}; EC=2.1.1.114 {ECO:0000255|HAMAP-Rule:MF_03190}; Flags: Precursor;+++[F6WGP0_HUMAN|Unreviewed]SubName: Full=Ubiquinone biosynthesis O-methyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000358243};"]
[5198,"'PFAS'",231,301,266,"01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++01100///Metabolic pathways+++00230///Purine metabolism",null,"M00048///Inosine monophosphate biosynthesis, PRPP + glutamine => IMP","R04463///5'-Phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)   ATP + 5'-Phosphoribosyl-N-formylglycinamide + L-Glutamine + H2O <=> ADP + Orthophosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + L-Glutamate","GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0004642///phosphoribosylformylglycinamidine synthase activity+++GO:0016874///ligase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity","GO:0042493///response to drug+++GO:0097065///anterior head development+++GO:0009156///ribonucleoside monophosphate biosynthetic process+++GO:0006541///glutamine metabolic process+++GO:0009168///purine ribonucleoside monophosphate biosynthetic process+++GO:0006189///'de novo' IMP biosynthetic process+++GO:0006164///purine nucleotide biosynthetic process","IPR017926///Glutamine amidotransferase+++IPR010918///PurM-like, C-terminal domain+++IPR036921///PurM-like, N-terminal domain superfamily+++IPR036604///Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily+++IPR029062///Class I glutamine amidotransferase-like+++IPR010073///Phosphoribosylformylglycinamidine synthase+++IPR036676///PurM-like, C-terminal domain superfamily","[PUR4_HUMAN|Reviewed]RecName: Full=Phosphoribosylformylglycinamidine synthase; Short=FGAM synthase; Short=FGAMS; EC=6.3.5.3; AltName: Full=Formylglycinamide ribonucleotide amidotransferase; Short=FGAR amidotransferase; Short=FGAR-AT; AltName: Full=Formylglycinamide ribotide amidotransferase;+++[A8K8N7_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase (FGAR amidotransferase), isoform CRA_b {ECO:0000313|EMBL:EAW90068.1}; SubName: Full=cDNA FLJ77779, highly similar to Homo sapiens phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (PFAS), mRNA {ECO:0000313|EMBL:BAF85091.1};+++[A8K9T9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75059, highly similar to Homo sapiens phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (PFAS), mRNA {ECO:0000313|EMBL:BAF85493.1};+++[B4DJ26_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase (FGAR amidotransferase), isoform CRA_c {ECO:0000313|EMBL:EAW90069.1}; SubName: Full=cDNA FLJ61288, highly similar to Phosphoribosylformylglycinamidine synthase {ECO:0000313|EMBL:BAG58688.1};+++[H0YGH1_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|Ensembl:ENSP00000443244}; Flags: Fragment;+++[J3KT98_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|Ensembl:ENSP00000462874}; Flags: Fragment;+++[J3KTL4_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|Ensembl:ENSP00000463045}; Flags: Fragment;+++[J3KTQ5_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|Ensembl:ENSP00000463103}; Flags: Fragment;+++[J3QL39_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|Ensembl:ENSP00000463362}; Flags: Fragment;+++[J3QSG0_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|Ensembl:ENSP00000464671};+++[J3QSH6_HUMAN|Unreviewed]SubName: Full=Phosphoribosylformylglycinamidine synthase {ECO:0000313|Ensembl:ENSP00000464689}; Flags: Fragment;+++[Q6P4B4_HUMAN|Unreviewed]SubName: Full=PFAS protein {ECO:0000313|EMBL:AAH63538.1}; Flags: Fragment;+++[Q9BR56_HUMAN|Unreviewed]SubName: Full=PFAS protein {ECO:0000313|EMBL:AAH06522.4}; Flags: Fragment;"]
[5214,"'PFKP'",3153,2843,2998,"01130///Biosynthesis of antibiotics+++00051///Fructose and mannose metabolism+++01120///Microbial metabolism in diverse environments+++04152///AMPK signaling pathway+++01230///Biosynthesis of amino acids+++01100///Metabolic pathways+++00680///Methane metabolism+++01200///Carbon metabolism+++00052///Galactose metabolism+++05230///Central carbon metabolism in cancer+++00030///Pentose phosphate pathway+++01110///Biosynthesis of secondary metabolites+++00010///Glycolysis / Gluconeogenesis+++03018///RNA degradation","H00069///Glycogen storage diseases (GSD)+++H01945///Glycogen storage disease type VII+++H01762///Muscle glycogen storage disease","M00001///Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate+++M00345///Formaldehyde assimilation, ribulose monophosphate pathway","R04779///ATP:D-fructose-6-phosphate 1-phosphotransferase   ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate+++R03239///ITP:D-tagatose 6-phosphate 1-phosphotransferase   ITP + D-Tagatose 6-phosphate <=> IDP + D-Tagatose 1,6-bisphosphate+++R00756///ATP:D-fructose-6-phosphate 1-phosphotransferase   ATP + D-Fructose 6-phosphate <=> ADP + D-Fructose 1,6-bisphosphate+++R03238///UTP:D-tagatose 6-phosphate 1-phosphotransferase   UTP + D-Tagatose 6-phosphate <=> UDP + D-Tagatose 1,6-bisphosphate+++R03236///ATP:D-tagatose-6-phosphate 1-phosphotransferase   D-Tagatose 6-phosphate + ATP <=> D-Tagatose 1,6-bisphosphate + ADP+++R03237///CTP:D-tagatose 6-phosphate 1-phosphotransferase   CTP + D-Tagatose 6-phosphate <=> CDP + D-Tagatose 1,6-bisphosphate","GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005945///6-phosphofructokinase complex+++GO:0070062///extracellular exosome","GO:0005524///ATP binding+++GO:0045296///cadherin binding+++GO:0046872///metal ion binding+++GO:0000166///nucleotide binding+++GO:0044877///protein-containing complex binding+++GO:0016208///AMP binding+++GO:0042802///identical protein binding+++GO:0070095///fructose-6-phosphate binding+++GO:0003824///catalytic activity+++GO:0048029///monosaccharide binding+++GO:0016740///transferase activity+++GO:0003872///6-phosphofructokinase activity+++GO:0016301///kinase activity","GO:0016310///phosphorylation+++GO:0008152///metabolic process+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0006096///glycolytic process+++GO:0051259///protein complex oligomerization+++GO:0006007///glucose catabolic process+++GO:0061615///glycolytic process through fructose-6-phosphate+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0061621///canonical glycolysis","IPR015912///Phosphofructokinase, conserved site+++IPR009161///ATP-dependent 6-phosphofructokinase, eukaryotic-type+++IPR035966///Phosphofructokinase superfamily+++IPR000023///Phosphofructokinase domain+++IPR022953///ATP-dependent 6-phosphofructokinase","[PFKAP_HUMAN|Reviewed]RecName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000255|HAMAP-Rule:MF_03184}; Short=ATP-PFK {ECO:0000255|HAMAP-Rule:MF_03184}; Short=PFK-P; EC=2.7.1.11 {ECO:0000255|HAMAP-Rule:MF_03184}; AltName: Full=6-phosphofructokinase type C; AltName: Full=Phosphofructo-1-kinase isozyme C; Short=PFK-C; AltName: Full=Phosphohexokinase {ECO:0000255|HAMAP-Rule:MF_03184};+++[B1APP6_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000313|Ensembl:ENSP00000408858}; Flags: Fragment;+++[B1APP8_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000313|Ensembl:ENSP00000370462}; SubName: Full=cDNA FLJ40373 fis, clone TESTI2035003, highly similar to 6-phosphofructokinase type C {ECO:0000313|EMBL:BAG53515.1};+++[H0Y3Y3_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000313|Ensembl:ENSP00000387871}; Flags: Fragment;+++[H0Y757_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000313|Ensembl:ENSP00000410275}; Flags: Fragment;+++[O14943_HUMAN|Unreviewed]SubName: Full=Phosphofructokinase-P {ECO:0000313|EMBL:BAA21891.1}; Flags: Fragment;+++[Q49A78_HUMAN|Unreviewed]SubName: Full=PFKP protein {ECO:0000313|EMBL:AAH43156.1};+++[Q5VSR5_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000313|Ensembl:ENSP00000385880}; Flags: Fragment;+++[V9GY25_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000313|Ensembl:ENSP00000476311}; Flags: Fragment;+++[V9GYV7_HUMAN|Unreviewed]SubName: Full=ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000313|Ensembl:ENSP00000477128}; Flags: Fragment;"]
[5241,"'PGR'",0,1,0.5,"04114///Oocyte meiosis+++05224///Breast cancer+++04914///Progesterone-mediated oocyte maturation+++04915///Estrogen signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005654///nucleoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0051117///ATPase binding+++GO:0046872///metal ion binding+++GO:0005496///steroid binding+++GO:0043565///sequence-specific DNA binding+++GO:0042802///identical protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005102///signaling receptor binding+++GO:0003707///steroid hormone receptor activity+++GO:0004879///nuclear receptor activity+++GO:0019899///enzyme binding+++GO:0008270///zinc ion binding+++GO:0008289///lipid binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0001542///ovulation from ovarian follicle+++GO:0007165///signal transduction+++GO:0050678///regulation of epithelial cell proliferation+++GO:0038001///paracrine signaling+++GO:0060748///tertiary branching involved in mammary gland duct morphogenesis+++GO:0007267///cell-cell signaling+++GO:0002070///epithelial cell maturation+++GO:0030879///mammary gland development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048286///lung alveolus development+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0010629///negative regulation of gene expression+++GO:0050847///progesterone receptor signaling pathway","IPR013088///Zinc finger, NHR/GATA-type+++IPR001628///Zinc finger, nuclear hormone receptor-type+++IPR000128///Progesterone receptor+++IPR000536///Nuclear hormone receptor, ligand-binding domain+++IPR035500///Nuclear hormone receptor-like domain superfamily+++IPR001723///Nuclear hormone receptor","[PRGR_HUMAN|Reviewed]RecName: Full=Progesterone receptor; Short=PR; AltName: Full=Nuclear receptor subfamily 3 group C member 3;+++[A0A087WXR4_HUMAN|Unreviewed]SubName: Full=Progesterone receptor {ECO:0000313|Ensembl:ENSP00000481227};+++[A0A0J9YVP1_HUMAN|Unreviewed]SubName: Full=Progesterone receptor {ECO:0000313|Ensembl:ENSP00000487607}; Flags: Fragment;+++[Q8NG42_HUMAN|Unreviewed]SubName: Full=Delta 6/2 progesterone receptor {ECO:0000313|EMBL:BAC11013.1}; SubName: Full=Progesterone receptor, isoform CRA_a {ECO:0000313|EMBL:EAW66997.1};+++[Q8NG44_HUMAN|Unreviewed]SubName: Full=Delta 3+6/2 progesterone receptor {ECO:0000313|EMBL:BAC11011.1}; SubName: Full=Progesterone receptor, isoform CRA_e {ECO:0000313|EMBL:EAW67001.1};+++[Q8NG45_HUMAN|Unreviewed]SubName: Full=Progesterone receptor, isoform CRA_f {ECO:0000313|EMBL:EAW67002.1};"]
[5264,"'PHYH'",128,77,102.5,"04146///Peroxisome","H00075///Refsum disease",null,null,"GO:0005782///peroxisomal matrix+++GO:0005829///cytosol+++GO:0005777///peroxisome","GO:0005515///protein binding+++GO:0008198///ferrous iron binding+++GO:0003824///catalytic activity+++GO:0031418///L-ascorbic acid binding+++GO:0051213///dioxygenase activity+++GO:0046872///metal ion binding+++GO:0048244///phytanoyl-CoA dioxygenase activity+++GO:0031406///carboxylic acid binding+++GO:0048037///cofactor binding+++GO:0016491///oxidoreductase activity","GO:0001561///fatty acid alpha-oxidation+++GO:0055114///oxidation-reduction process+++GO:0006625///protein targeting to peroxisome+++GO:0006103///2-oxoglutarate metabolic process+++GO:0006720///isoprenoid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0097089///methyl-branched fatty acid metabolic process","IPR008775///Phytanoyl-CoA dioxygenase","[PAHX_HUMAN|Reviewed]RecName: Full=Phytanoyl-CoA dioxygenase, peroxisomal; EC=1.14.11.18; AltName: Full=Phytanic acid oxidase; AltName: Full=Phytanoyl-CoA alpha-hydroxylase; Short=PhyH; Flags: Precursor;+++[B1ALH6_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA dioxygenase, peroxisomal {ECO:0000313|Ensembl:ENSP00000380126};+++[C9IYS5_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA dioxygenase, peroxisomal {ECO:0000313|Ensembl:ENSP00000412525}; Flags: Fragment;+++[C9JR86_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA dioxygenase, peroxisomal {ECO:0000313|Ensembl:ENSP00000420117}; Flags: Fragment;+++[Q6FGQ2_HUMAN|Unreviewed]SubName: Full=PHYH protein {ECO:0000313|EMBL:CAG46852.1}; Flags: Fragment;"]
[5287,"'PIK3C2B'",160.15,265.83,212.99,"00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++01100///Metabolic pathways",null,null,"R03362///ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase   ATP + 1-Phosphatidyl-D-myo-inositol <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3-phosphate+++R05795///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase   ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate","GO:0005654///nucleoplasm+++GO:0005886///plasma membrane+++GO:0030139///endocytic vesicle+++GO:0005634///nucleus+++GO:0005942///phosphatidylinositol 3-kinase complex+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0035091///phosphatidylinositol binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0001727///lipid kinase activity+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0035005///1-phosphatidylinositol-4-phosphate 3-kinase activity","GO:0046854///phosphatidylinositol phosphorylation+++GO:0016310///phosphorylation+++GO:0008150///biological_process+++GO:0016477///cell migration+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0009267///cellular response to starvation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:1905037///autophagosome organization+++GO:0016236///macroautophagy+++GO:0043491///protein kinase B signaling","IPR029071///Ubiquitin-like domain superfamily+++IPR036871///PX domain superfamily+++IPR035892///C2 domain superfamily+++IPR011009///Protein kinase-like domain superfamily+++IPR001683///Phox homologous domain+++IPR000008///C2 domain+++IPR000341///Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain+++IPR002420///Phosphatidylinositol 3-kinase, C2 domain+++IPR015433///Phosphatidylinositol kinase+++IPR001263///Phosphoinositide 3-kinase, accessory (PIK) domain+++IPR018936///Phosphatidylinositol 3/4-kinase, conserved site+++IPR000403///Phosphatidylinositol 3-/4-kinase, catalytic domain+++IPR016024///Armadillo-type fold+++IPR036940///Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily","[P3C2B_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Short=PI3K-C2-beta; Short=PtdIns-3-kinase C2 subunit beta; EC=2.7.1.154; AltName: Full=C2-PI3K; AltName: Full=Phosphoinositide 3-kinase-C2-beta;+++[A2RUF7_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta {ECO:0000313|EMBL:AGC09602.1}; SubName: Full=Phosphoinositide-3-kinase, class 2, beta polypeptide {ECO:0000313|EMBL:AAI32877.1}; SubName: Full=Phosphoinositide-3-kinase, class 2, beta polypeptide, isoform CRA_b {ECO:0000313|EMBL:EAW91514.1};+++[B7ZM86_HUMAN|Unreviewed]SubName: Full=PIK3C2B protein {ECO:0000313|EMBL:AAI44343.1};+++[F5GWN5_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta {ECO:0000313|Ensembl:ENSP00000400561};+++[Q4LE65_HUMAN|Unreviewed]SubName: Full=PIK3C2B variant protein {ECO:0000313|EMBL:BAE06088.1}; Flags: Fragment;+++[Q5SW97_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta {ECO:0000313|Ensembl:ENSP00000409554}; Flags: Fragment;+++[Q5SW98_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta {ECO:0000313|Ensembl:ENSP00000401795}; Flags: Fragment;+++[Q5SWA0_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta {ECO:0000313|Ensembl:ENSP00000356152}; Flags: Fragment;"]
[5305,"'PIP4K2A'",554,656,605,"04070///Phosphatidylinositol signaling system+++00562///Inositol phosphate metabolism+++04810///Regulation of actin cytoskeleton",null,null,"R05803///ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase   ATP + 1-Phosphatidyl-1D-myo-inositol 5-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate","GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0016309///1-phosphatidylinositol-5-phosphate 4-kinase activity+++GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0052811///1-phosphatidylinositol-3-phosphate 4-kinase activity","GO:0046854///phosphatidylinositol phosphorylation+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0046488///phosphatidylinositol metabolic process+++GO:0016310///phosphorylation+++GO:2000786///positive regulation of autophagosome assembly+++GO:0010506///regulation of autophagy+++GO:0006644///phospholipid metabolic process+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0035855///megakaryocyte development","IPR023610///Phosphatidylinositol-4-phosphate 5-kinase+++IPR027484///Phosphatidylinositol-4-phosphate 5-kinase, N-terminal+++IPR002498///Phosphatidylinositol-4-phosphate 5-kinase, core+++IPR027483///Phosphatidylinositol-4-phosphate 5-kinase, C-terminal","[PI42A_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; EC=2.7.1.149; AltName: Full=1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; AltName: Full=Diphosphoinositide kinase 2-alpha; AltName: Full=PIP5KIII; AltName: Full=Phosphatidylinositol 5-phosphate 4-kinase type II alpha; Short=PI(5)P 4-kinase type II alpha; Short=PIP4KII-alpha; AltName: Full=PtdIns(4)P-5-kinase B isoform; AltName: Full=PtdIns(4)P-5-kinase C isoform; AltName: Full=PtdIns(5)P-4-kinase isoform 2-alpha;+++[H7BXS3_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha {ECO:0000313|Ensembl:ENSP00000326294};+++[L8EAD2_HUMAN|Unreviewed]SubName: Full=Alternative protein PIP4K2A {ECO:0000313|EMBL:CCQ43293.1};+++[S4R320_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha {ECO:0000313|Ensembl:ENSP00000473858}; Flags: Fragment;"]
[5322,"'PLA2G5'",93,59,76,"00590///Arachidonic acid metabolism+++01100///Metabolic pathways+++00591///Linoleic acid metabolism+++01110///Biosynthesis of secondary metabolites+++04014///Ras signaling pathway+++00565///Ether lipid metabolism+++04270///Vascular smooth muscle contraction+++00564///Glycerophospholipid metabolism+++04975///Fat digestion and absorption+++04972///Pancreatic secretion+++00592///alpha-Linolenic acid metabolism",null,null,"R07387///plasmanylcholine 2-acylhydrolase   1-Radyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-Organyl-2-lyso-sn-glycero-3-phosphocholine + Carboxylate+++R01315///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid+++R07859///Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + (9Z,12Z,15Z)-Octadecatrienoic acid+++R07379///plasmenylethanolamine 2-acylhydrolase   O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + Carboxylate+++R01317///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Arachidonate+++R02053///phosphatidylethanolamine 2-acylhydrolase   Phosphatidylethanolamine + H2O <=> 1-Acyl-sn-glycero-3-phosphoethanolamine + Fatty acid+++R07064///phosphatidylcholine 2-acylhydrolase   Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Linoleate","GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0048471///perinuclear region of cytoplasm","GO:0005543///phospholipid binding+++GO:0004623///phospholipase A2 activity+++GO:0008201///heparin binding+++GO:0005509///calcium ion binding+++GO:0047498///calcium-dependent phospholipase A2 activity+++GO:0102567///phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine)+++GO:0016787///hydrolase activity+++GO:0102568///phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine)+++GO:0046872///metal ion binding","GO:0036152///phosphatidylethanolamine acyl-chain remodeling+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0036149///phosphatidylinositol acyl-chain remodeling+++GO:0034097///response to cytokine+++GO:0006629///lipid metabolic process+++GO:0050482///arachidonic acid secretion+++GO:0036150///phosphatidylserine acyl-chain remodeling+++GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0043030///regulation of macrophage activation+++GO:0006644///phospholipid metabolic process+++GO:0051591///response to cAMP+++GO:0019370///leukotriene biosynthetic process+++GO:0034374///low-density lipoprotein particle remodeling+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0006663///platelet activating factor biosynthetic process+++GO:0016042///lipid catabolic process+++GO:0010518///positive regulation of phospholipase activity+++GO:0050728///negative regulation of inflammatory response+++GO:0006654///phosphatidic acid biosynthetic process","IPR001211///Phospholipase A2+++IPR016090///Phospholipase A2 domain+++IPR033113///Phospholipase A2, histidine active site+++IPR033112///Phospholipase A2, aspartic acid active site+++IPR036444///Phospholipase A2 domain superfamily","[PA2G5_HUMAN|Reviewed]RecName: Full=Calcium-dependent phospholipase A2; EC=3.1.1.4; AltName: Full=Group V phospholipase A2; AltName: Full=PLA2-10; AltName: Full=Phosphatidylcholine 2-acylhydrolase 5; Flags: Precursor;"]
[53340,"'SPA17'",40,47,43.5,{"$nulls":4},"GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0097228///sperm principal piece+++GO:0031514///motile cilium+++GO:0005929///cilium+++GO:0005737///cytoplasm+++GO:0035686///sperm fibrous sheath","GO:0005516///calmodulin binding+++GO:0005515///protein binding","GO:0007283///spermatogenesis+++GO:0003351///epithelial cilium movement+++GO:0007339///binding of sperm to zona pellucida+++GO:0007338///single fertilization","IPR003117///cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain+++IPR000048///IQ motif, EF-hand binding site+++IPR012105///Sperm surface protein Sp17","[SP17_HUMAN|Reviewed]RecName: Full=Sperm surface protein Sp17; AltName: Full=Cancer/testis antigen 22; Short=CT22; AltName: Full=Sp17-1; AltName: Full=Sperm autoantigenic protein 17; Short=Sperm protein 17;+++[A0A172Q397_HUMAN|Unreviewed]SubName: Full=Sperm protein 17 {ECO:0000313|EMBL:AND76668.1}; Flags: Fragment;+++[Q05D07_HUMAN|Unreviewed]SubName: Full=SPA17 protein {ECO:0000313|EMBL:AAH19224.1}; Flags: Fragment;"]
[5339,"'PLEC'",18375.97,18986,18680.985,null,"H00585///Epidermolysis bullosa, hemidesmosomal+++H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0030056///hemidesmosome+++GO:0043292///contractile fiber+++GO:0005856///cytoskeleton+++GO:0005903///brush border+++GO:0048471///perinuclear region of cytoplasm+++GO:0005886///plasma membrane+++GO:0005925///focal adhesion+++GO:0016021///integral component of membrane+++GO:0043034///costamere+++GO:0016528///sarcoplasm+++GO:0042383///sarcolemma+++GO:0016020///membrane+++GO:0045111///intermediate filament cytoskeleton+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0030054///cell junction","GO:0005200///structural constituent of cytoskeleton+++GO:0005198///structural molecule activity+++GO:0030506///ankyrin binding+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0045296///cadherin binding+++GO:0003723///RNA binding+++GO:0003779///actin binding+++GO:0008092///cytoskeletal protein binding","GO:0031581///hemidesmosome assembly+++GO:0045104///intermediate filament cytoskeleton organization+++GO:0042060///wound healing+++GO:0007010///cytoskeleton organization","IPR035915///Plakin repeat superfamily+++IPR001589///Actinin-type actin-binding domain, conserved site+++IPR030269///Plectin+++IPR018159///Spectrin/alpha-actinin+++IPR036872///CH domain superfamily+++IPR001452///SH3 domain+++IPR001715///Calponin homology domain+++IPR029926///Dystonin-like+++IPR005326///Plectin/S10, N-terminal+++IPR001101///Plectin repeat+++IPR036388///Winged helix-like DNA-binding domain superfamily","[PLEC_HUMAN|Reviewed]RecName: Full=Plectin; Short=PCN; Short=PLTN; AltName: Full=Hemidesmosomal protein 1; Short=HD1; AltName: Full=Plectin-1;+++[D3DWL0_HUMAN|Unreviewed]SubName: Full=Plectin 1, intermediate filament binding protein 500kDa, isoform CRA_b {ECO:0000313|EMBL:EAW82173.1};+++[E9PIA2_HUMAN|Unreviewed]SubName: Full=Plectin {ECO:0000313|Ensembl:ENSP00000436702}; Flags: Fragment;+++[E9PKG0_HUMAN|Unreviewed]SubName: Full=Plectin {ECO:0000313|Ensembl:ENSP00000433557}; Flags: Fragment;+++[E9PMV1_HUMAN|Unreviewed]SubName: Full=Plectin {ECO:0000313|Ensembl:ENSP00000437303}; Flags: Fragment;+++[E9PQ28_HUMAN|Unreviewed]SubName: Full=Plectin {ECO:0000313|Ensembl:ENSP00000434490}; Flags: Fragment;+++[H0YDN1_HUMAN|Unreviewed]SubName: Full=Plectin {ECO:0000313|Ensembl:ENSP00000433982}; Flags: Fragment;+++[Q8WXV5_HUMAN|Unreviewed]SubName: Full=HCG1994702 {ECO:0000313|EMBL:EAW82175.1}; SubName: Full=Plectin isoform 1b {ECO:0000313|EMBL:AAL37483.1}; Flags: Fragment;+++[Q8WXV6_HUMAN|Unreviewed]SubName: Full=Plectin isoform 1a {ECO:0000313|EMBL:AAL37482.1}; Flags: Fragment;"]
[5356,"'PLRG1'",484,454,469,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0016021///integral component of membrane+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0000974///Prp19 complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0031965///nuclear membrane+++GO:0016020///membrane+++GO:0001650///fibrillar center+++GO:0071013///catalytic step 2 spliceosome+++GO:0005662///DNA replication factor A complex+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0005681///spliceosomal complex+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:0034504///protein localization to nucleus+++GO:0006397///mRNA processing","IPR001680///WD40 repeat+++IPR036322///WD40-repeat-containing domain superfamily+++IPR017986///WD40-repeat-containing domain+++IPR020472///G-protein beta WD-40 repeat+++IPR019775///WD40 repeat, conserved site+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[PLRG1_HUMAN|Reviewed]RecName: Full=Pleiotropic regulator 1;+++[B7Z982_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57451, highly similar to Pleiotropic regulator 1 {ECO:0000313|EMBL:BAH14218.1};+++[D6RA26_HUMAN|Unreviewed]SubName: Full=Pleiotropic regulator 1 {ECO:0000313|Ensembl:ENSP00000423454}; Flags: Fragment;+++[D6RE04_HUMAN|Unreviewed]SubName: Full=Pleiotropic regulator 1 {ECO:0000313|Ensembl:ENSP00000425147};+++[H0YA24_HUMAN|Unreviewed]SubName: Full=Pleiotropic regulator 1 {ECO:0000313|Ensembl:ENSP00000425914}; Flags: Fragment;+++[H0YAA2_HUMAN|Unreviewed]SubName: Full=Pleiotropic regulator 1 {ECO:0000313|Ensembl:ENSP00000426497}; Flags: Fragment;"]
[537,"'ATP6AP1'",6998,6630,6814,"05120///Epithelial cell signaling in Helicobacter pylori infection+++05110///Vibrio cholerae infection+++05323///Rheumatoid arthritis+++04142///Lysosome+++04145///Phagosome+++05165///Human papillomavirus infection+++05152///Tuberculosis+++01100///Metabolic pathways+++00190///Oxidative phosphorylation+++05161///Hepatitis B",null,"M00160///V-type ATPase, eukaryotes",null,"GO:0010008///endosome membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0005783///endoplasmic reticulum+++GO:0016469///proton-transporting two-sector ATPase complex+++GO:0033180///proton-transporting V-type ATPase, V1 domain+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome","GO:0046933///proton-transporting ATP synthase activity, rotational mechanism+++GO:0017137///Rab GTPase binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0046961///proton-transporting ATPase activity, rotational mechanism+++GO:0005215///transporter activity","GO:0015991///ATP hydrolysis coupled proton transport+++GO:0045780///positive regulation of bone resorption+++GO:2001206///positive regulation of osteoclast development+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045921///positive regulation of exocytosis+++GO:0008286///insulin receptor signaling pathway+++GO:0006811///ion transport+++GO:0006879///cellular iron ion homeostasis+++GO:0051656///establishment of organelle localization+++GO:0033572///transferrin transport+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0034220///ion transmembrane transport+++GO:0045851///pH reduction+++GO:0036295///cellular response to increased oxygen levels+++GO:1902600///proton transmembrane transport","IPR008388///ATPase, V1 complex, subunit S1","[VAS1_HUMAN|Reviewed]RecName: Full=V-type proton ATPase subunit S1; Short=V-ATPase subunit S1; AltName: Full=Protein XAP-3; AltName: Full=V-ATPase Ac45 subunit; AltName: Full=V-ATPase S1 accessory protein; AltName: Full=Vacuolar proton pump subunit S1; Flags: Precursor;+++[A0A0C4DGX8_HUMAN|Unreviewed]SubName: Full=ATPase, H+ transporting, lysosomal accessory protein 1, isoform CRA_c {ECO:0000313|EMBL:EAW72714.1}; SubName: Full=V-type proton ATPase subunit S1 {ECO:0000313|Ensembl:ENSP00000482243};+++[A6NLC6_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit S1 {ECO:0000313|Ensembl:ENSP00000398511}; Flags: Fragment;+++[A6QRJ1_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit S1 {ECO:0000313|Ensembl:ENSP00000392375}; Flags: Fragment;+++[F2Z3L8_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit S1 {ECO:0000313|Ensembl:ENSP00000411209};+++[H7C0T7_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit S1 {ECO:0000313|Ensembl:ENSP00000396643}; Flags: Fragment;+++[H7C2Y8_HUMAN|Unreviewed]SubName: Full=V-type proton ATPase subunit S1 {ECO:0000313|Ensembl:ENSP00000408470}; Flags: Fragment;"]
[53834,"'FGFRL1'",4960,4589,4774.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0044291///cell-cell contact zone+++GO:0030133///transport vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005007///fibroblast growth factor-activated receptor activity+++GO:0017134///fibroblast growth factor binding+++GO:0008201///heparin binding","GO:0034446///substrate adhesion-dependent cell spreading+++GO:0008285///negative regulation of cell proliferation+++GO:0060539///diaphragm development+++GO:0051291///protein heterooligomerization+++GO:0098742///cell-cell adhesion via plasma-membrane adhesion molecules+++GO:0003179///heart valve morphogenesis+++GO:0051260///protein homooligomerization+++GO:0060412///ventricular septum morphogenesis+++GO:0001501///skeletal system development+++GO:0008543///fibroblast growth factor receptor signaling pathway","IPR003598///Immunoglobulin subtype 2+++IPR013783///Immunoglobulin-like fold+++IPR003599///Immunoglobulin subtype+++IPR013098///Immunoglobulin I-set+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily","[FGRL1_HUMAN|Reviewed]RecName: Full=Fibroblast growth factor receptor-like 1; Short=FGF receptor-like protein 1; AltName: Full=FGF homologous factor receptor; AltName: Full=FGFR-like protein; AltName: Full=Fibroblast growth factor receptor 5; Short=FGFR-5; Flags: Precursor;+++[A0PJ49_HUMAN|Unreviewed]SubName: Full=FGFRL1 protein {ECO:0000313|EMBL:AAH15228.1}; Flags: Fragment;+++[D6RBN8_HUMAN|Unreviewed]SubName: Full=Fibroblast growth factor receptor-like 1 {ECO:0000313|Ensembl:ENSP00000424037}; Flags: Fragment;+++[D6REM7_HUMAN|Unreviewed]SubName: Full=Fibroblast growth factor receptor-like 1 {ECO:0000313|Ensembl:ENSP00000426740}; Flags: Fragment;"]
[53944,"'CSNK1G1'",448,617.99,532.995,"04341///Hedgehog signaling pathway - fly+++04340///Hedgehog signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0006897///endocytosis+++GO:0016055///Wnt signaling pathway+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0090263///positive regulation of canonical Wnt signaling pathway","IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site+++IPR022247///Casein kinase 1 gamma C-terminal+++IPR000719///Protein kinase domain","[KC1G1_HUMAN|Reviewed]RecName: Full=Casein kinase I isoform gamma-1; Short=CKI-gamma 1; EC=2.7.11.1;+++[A0A024R5W3_HUMAN|Unreviewed]SubName: Full=HCG2004507, isoform CRA_a {ECO:0000313|EMBL:EAW77676.1};+++[A0A0U1RQG9_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000488990}; Flags: Fragment;+++[A0A0U1RQH9_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489008};+++[A0A0U1RQK2_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489046}; Flags: Fragment;+++[A0A0U1RQK6_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489050}; Flags: Fragment;+++[A0A0U1RQN5_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489090}; Flags: Fragment;+++[A0A0U1RQT7_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489165};+++[A0A0U1RQU4_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489172}; Flags: Fragment;+++[A0A0U1RQY7_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489233};+++[A0A0U1RR14_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489277}; Flags: Fragment;+++[A0A0U1RR31_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489310}; Flags: Fragment;+++[A0A0U1RRH5_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000489534};+++[Q8IXA3_HUMAN|Unreviewed]SubName: Full=Casein kinase I gamma 1 isoform {ECO:0000313|EMBL:AAO12758.2}; SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000476088}; SubName: Full=HCG2004507, isoform CRA_d {ECO:0000313|EMBL:EAW77677.1};+++[U3KQA5_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000475686};+++[U3KQB3_HUMAN|Unreviewed]SubName: Full=Casein kinase I isoform gamma-1 {ECO:0000313|Ensembl:ENSP00000475724};"]
[54069,"'MIS18A'",62,56,59,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0000785///chromatin+++GO:0000775///chromosome, centromeric region","GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0051301///cell division+++GO:0034080///CENP-A containing nucleosome assembly+++GO:0007049///cell cycle+++GO:0007059///chromosome segregation+++GO:0044030///regulation of DNA methylation","IPR004910///Yippee/Mis18/Cereblon+++IPR034752///Mis18 domain","[MS18A_HUMAN|Reviewed]RecName: Full=Protein Mis18-alpha; AltName: Full=FAPP1-associated protein 1;"]
[54148,"'MRPL39'",142,126,134,{"$nulls":4},"GO:0005761///mitochondrial ribosome+++GO:0005840///ribosome+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005743///mitochondrial inner membrane","GO:0000166///nucleotide binding+++GO:0003723///RNA binding","GO:0070125///mitochondrial translational elongation+++GO:0070126///mitochondrial translational termination","IPR012676///TGS-like+++IPR018163///Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily+++IPR012675///Beta-grasp domain superfamily","[RM39_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L39, mitochondrial; Short=L39mt; Short=MRP-L39; AltName: Full=39S ribosomal protein L5, mitochondrial; Short=L5mt; Short=MRP-L5; AltName: Full=Mitochondrial large ribosomal subunit protein mL39 {ECO:0000303|PubMed:25278503};+++[C9JG87_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L39, mitochondrial {ECO:0000313|Ensembl:ENSP00000404426}; Flags: Fragment;"]
[5426,"'POLE'",134,166,150,"05166///HTLV-I infection+++03410///Base excision repair+++00240///Pyrimidine metabolism+++03030///DNA replication+++03420///Nucleotide excision repair+++01100///Metabolic pathways+++00230///Purine metabolism","H00269///Primary microcephaly (MCPH)","M00263///DNA polymerase epsilon complex","R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dGTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dATP + DNA <=> Diphosphate + DNA+++R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dTTP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dCTP + DNA <=> Diphosphate + DNA","GO:0005886///plasma membrane+++GO:0008622///epsilon DNA polymerase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0008310///single-stranded DNA 3'-5' exodeoxyribonuclease activity+++GO:0000166///nucleotide binding+++GO:0003887///DNA-directed DNA polymerase activity+++GO:0051536///iron-sulfur cluster binding+++GO:0016779///nucleotidyltransferase activity+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0006272///leading strand elongation+++GO:0006260///DNA replication+++GO:0045004///DNA replication proofreading+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006287///base-excision repair, gap-filling+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006281///DNA repair+++GO:0048568///embryonic organ development+++GO:0000278///mitotic cell cycle+++GO:0071897///DNA biosynthetic process+++GO:0000731///DNA synthesis involved in DNA repair+++GO:0006297///nucleotide-excision repair, DNA gap filling","IPR036397///Ribonuclease H superfamily+++IPR012337///Ribonuclease H-like superfamily+++IPR029703///DNA polymerase epsilon catalytic subunit+++IPR006134///DNA-directed DNA polymerase, family B, multifunctional domain+++IPR006172///DNA-directed DNA polymerase, family B+++IPR013697///DNA polymerase epsilon, catalytic subunit A, C-terminal+++IPR006133///DNA-directed DNA polymerase, family B, exonuclease domain","[DPOE1_HUMAN|Reviewed]RecName: Full=DNA polymerase epsilon catalytic subunit A; EC=2.7.7.7; AltName: Full=DNA polymerase II subunit A;+++[A0A087WW42_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029}; Flags: Fragment;+++[A0A087WX51_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029}; Flags: Fragment;+++[D3DXI9_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029};+++[F5H1D6_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029};+++[F5H7E4_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029};+++[Q96IE1_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029}; Flags: Fragment;+++[Q9UNE8_HUMAN|Unreviewed]SubName: Full=DNA polymerase epsilon catalytic subunit isoform b {ECO:0000313|EMBL:AAD45663.1}; Flags: Fragment;+++[Q9UNE9_HUMAN|Unreviewed]SubName: Full=DNA polymerase epsilon catalytic subunit isoform a {ECO:0000313|EMBL:AAD45662.1}; SubName: Full=HCG2007366 {ECO:0000313|EMBL:EAW54816.1}; Flags: Fragment;+++[Q9UNF3_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029};+++[Q9Y5S4_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029};+++[Q9Y5S5_HUMAN|Unreviewed]RecName: Full=DNA polymerase epsilon catalytic subunit {ECO:0000256|RuleBase:RU365029}; EC=2.7.7.7 {ECO:0000256|RuleBase:RU365029};"]
[5435,"'POLR2F'",578,325,451.5,"00230///Purine metabolism+++00240///Pyrimidine metabolism+++03020///RNA polymerase+++04623///Cytosolic DNA-sensing pathway+++05169///Epstein-Barr virus infection+++05016///Huntington's disease+++01100///Metabolic pathways",null,"M00180///RNA polymerase II, eukaryotes+++M00181///RNA polymerase III, eukaryotes+++M00182///RNA polymerase I, eukaryotes","R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA","GO:0005666///RNA polymerase III complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0001650///fibrillar center+++GO:0005665///RNA polymerase II, core complex+++GO:0005736///RNA polymerase I complex","GO:0001056///RNA polymerase III activity+++GO:0003677///DNA binding+++GO:0001055///RNA polymerase II activity+++GO:0001054///RNA polymerase I activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006366///transcription by RNA polymerase II+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006370///7-methylguanosine mRNA capping+++GO:0006363///termination of RNA polymerase I transcription+++GO:0060964///regulation of gene silencing by miRNA+++GO:0008543///fibroblast growth factor receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006383///transcription by RNA polymerase III+++GO:0016070///RNA metabolic process+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006351///transcription, DNA-templated","IPR006110///RNA polymerase, subunit omega/K/RPB6+++IPR036161///RPB6/omega subunit-like superfamily+++IPR020708///DNA-directed RNA polymerase, 14-18kDa subunit, conserved site+++IPR028363///DNA-directed RNA polymerase, subunit  RPB6+++IPR012293///RNA polymerase subunit, RPB6/omega+++IPR006111///Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit","[RPAB2_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2; Short=RNA polymerases I, II, and III subunit ABC2; AltName: Full=DNA-directed RNA polymerase II subunit F; AltName: Full=DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide; AltName: Full=RPABC14.4; Short=RPB14.4; AltName: Full=RPB6 homolog; AltName: Full=RPC15;+++[B0QYL8_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000384112};+++[B0QYL9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000385725};+++[F8WC47_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000406826};+++[H0Y2U7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000332130}; Flags: Fragment;+++[H0Y439_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000389307}; Flags: Fragment;+++[U3KPV3_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000475257};+++[U3KPY1_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000475343}; Flags: Fragment;+++[U3KQB0_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000475707};+++[U3KQQ7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000476132};+++[U3KQS8_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerases I, II, and III subunit RPABC2 {ECO:0000313|Ensembl:ENSP00000476187};"]
[54431,"'DNAJC10'",1273,1615,1444,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0016020///membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0016021///integral component of membrane+++GO:0034663///endoplasmic reticulum chaperone complex+++GO:0005783///endoplasmic reticulum+++GO:0005623///cell","GO:0015035///protein disulfide oxidoreductase activity+++GO:0030544///Hsp70 protein binding+++GO:0051787///misfolded protein binding+++GO:0016491///oxidoreductase activity+++GO:0015036///disulfide oxidoreductase activity+++GO:0016671///oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor+++GO:0051087///chaperone binding+++GO:0051117///ATPase binding+++GO:0005515///protein binding+++GO:0001671///ATPase activator activity","GO:0034976///response to endoplasmic reticulum stress+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0045454///cell redox homeostasis+++GO:0070059///intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress+++GO:0032781///positive regulation of ATPase activity+++GO:0001933///negative regulation of protein phosphorylation+++GO:0055114///oxidation-reduction process+++GO:0034975///protein folding in endoplasmic reticulum","IPR017937///Thioredoxin, conserved site+++IPR036249///Thioredoxin-like superfamily+++IPR035673///ERdj5, first thioredoxin domain+++IPR001623///DnaJ domain+++IPR021170///DnaJ homologue subfamily C member 10+++IPR036869///Chaperone J-domain superfamily+++IPR035674///ERdj5, C-terminal thioredoxin domain+++IPR013766///Thioredoxin domain","[DJC10_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily C member 10; EC=1.8.4.-; AltName: Full=Endoplasmic reticulum DNA J domain-containing protein 5; Short=ER-resident protein ERdj5; Short=ERdj5; AltName: Full=Macrothioredoxin; Short=MTHr; Flags: Precursor;+++[A0A087WXH7_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 10 {ECO:0000313|Ensembl:ENSP00000481044};+++[E7EP04_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 10 {ECO:0000313|Ensembl:ENSP00000389483};+++[H7C1G0_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 10 {ECO:0000313|Ensembl:ENSP00000400096}; Flags: Fragment;+++[Q71S60_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily C member 10 {ECO:0000313|Ensembl:ENSP00000491817}; SubName: Full=Endoplasmic reticulum DnaJ-PDI fusion protein 2 {ECO:0000313|EMBL:AAQ14565.1};+++[Q8N4C5_HUMAN|Unreviewed]SubName: Full=DNAJC10 protein {ECO:0000313|EMBL:AAH34713.1};"]
[54457,"'TAF7L'",15,34,24.5,"03022///Basal transcription factors",{"$nulls":3},"GO:0005669///transcription factor TFIID complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0003713///transcription coactivator activity+++GO:0003674///molecular_function+++GO:0044212///transcription regulatory region DNA binding+++GO:0035035///histone acetyltransferase binding+++GO:0008134///transcription factor binding","GO:0007283///spermatogenesis+++GO:0007275///multicellular organism development+++GO:0008150///biological_process+++GO:0030154///cell differentiation+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0006367///transcription initiation from RNA polymerase II promoter","IPR006751///TAFII55 protein, conserved region+++IPR037817///Transcription initiation factor TFIID subunit 7","[TAF7L_HUMAN|Reviewed]RecName: Full=Transcription initiation factor TFIID subunit 7-like; AltName: Full=Cancer/testis antigen 40; Short=CT40; AltName: Full=RNA polymerase II TBP-associated factor subunit Q; AltName: Full=TATA box-binding protein-associated factor 50 kDa; AltName: Full=Transcription initiation factor TFIID 50 kDa subunit;+++[A0A024RCI3_HUMAN|Unreviewed]SubName: Full=TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa, isoform CRA_a {ECO:0000313|EMBL:EAX02850.1};+++[L8E974_HUMAN|Unreviewed]SubName: Full=Alternative protein TAF7L {ECO:0000313|EMBL:CCQ43724.1};"]
[54472,"'TOLLIP'",1302,1031,1166.5,"04620///Toll-like receptor signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0035580///specific granule lumen+++GO:0045323///interleukin-1 receptor complex+++GO:0016604///nuclear body+++GO:0035578///azurophil granule lumen+++GO:0005737///cytoplasm+++GO:0045092///interleukin-18 receptor complex","GO:0005150///interleukin-1, type I receptor binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0019900///kinase binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0035325///Toll-like receptor binding+++GO:0043130///ubiquitin binding+++GO:0032183///SUMO binding+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0002376///immune system process+++GO:0007165///signal transduction+++GO:0030855///epithelial cell differentiation+++GO:0045087///innate immune response+++GO:0035556///intracellular signal transduction+++GO:0006954///inflammatory response+++GO:0045321///leukocyte activation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006914///autophagy+++GO:0036010///protein localization to endosome+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0033235///positive regulation of protein sumoylation+++GO:0043312///neutrophil degranulation+++GO:0007267///cell-cell signaling","IPR037301///Toll-interacting protein, C2 domain+++IPR035892///C2 domain superfamily+++IPR009060///UBA-like superfamily+++IPR003892///Ubiquitin system component Cue+++IPR000008///C2 domain","[TOLIP_HUMAN|Reviewed]RecName: Full=Toll-interacting protein;+++[B3KR28_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33531 fis, clone BRAMY2007255, highly similar to Toll-interacting protein {ECO:0000313|EMBL:BAG52240.1};+++[E7EN89_HUMAN|Unreviewed]SubName: Full=Toll interacting protein, isoform CRA_b {ECO:0000313|EMBL:EAX02435.1}; SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000263646};+++[E9PNS3_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000432778};+++[E9PP67_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000436393};+++[E9PQ25_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000434494}; Flags: Fragment;+++[F2Z2Y8_HUMAN|Unreviewed]SubName: Full=Toll-interacting protein {ECO:0000313|Ensembl:ENSP00000432668};+++[Q6FIE9_HUMAN|Unreviewed]SubName: Full=TOLLIP protein {ECO:0000313|EMBL:CAG38508.1}; SubName: Full=Toll interacting protein {ECO:0000313|EMBL:AAX22229.1}; SubName: Full=Toll interacting protein, isoform CRA_a {ECO:0000313|EMBL:EAX02433.1}; SubName: Full=cDNA, FLJ96670, Homo sapiens toll interacting protein (TOLLIP), mRNA {ECO:0000313|EMBL:BAG37964.1};+++[Q8N8J5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39374 fis, clone PEBLM2008576, highly similar to Homo sapiens TOLLIP protein {ECO:0000313|EMBL:BAC04844.1};"]
[545,"'ATR'",170,194,182,"04115///p53 signaling pathway+++05166///HTLV-I infection+++03460///Fanconi anemia pathway+++04110///Cell cycle+++04214///Apoptosis - fly+++05165///Human papillomavirus infection+++04218///Cellular senescence","H00992///Seckel syndrome+++H00037///Alveolar rhabdomyosarcoma","M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005694///chromosome+++GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0016605///PML body","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0032407///MutSalpha complex binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0003677///DNA binding+++GO:0032405///MutLalpha complex binding+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0005524///ATP binding","GO:0070198///protein localization to chromosome, telomeric region+++GO:0007275///multicellular organism development+++GO:0008156///negative regulation of DNA replication+++GO:1900034///regulation of cellular response to heat+++GO:0006281///DNA repair+++GO:0000077///DNA damage checkpoint+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator+++GO:1904884///positive regulation of telomerase catalytic core complex assembly+++GO:0097694///establishment of RNA localization to telomere+++GO:0071480///cellular response to gamma radiation+++GO:0042493///response to drug+++GO:0036297///interstrand cross-link repair+++GO:0032212///positive regulation of telomere maintenance via telomerase+++GO:0034644///cellular response to UV+++GO:0006260///DNA replication+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006310///DNA recombination+++GO:0018105///peptidyl-serine phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0097695///establishment of protein-containing complex localization to telomere+++GO:0090399///replicative senescence+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated","IPR011009///Protein kinase-like domain superfamily+++IPR014009///PIK-related kinase+++IPR018936///Phosphatidylinositol 3/4-kinase, conserved site+++IPR011989///Armadillo-like helical+++IPR003152///FATC domain+++IPR003151///PIK-related kinase, FAT+++IPR036940///Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily+++IPR021133///HEAT, type 2+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR012993///UME domain+++IPR016024///Armadillo-type fold+++IPR000403///Phosphatidylinositol 3-/4-kinase, catalytic domain","[ATR_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase ATR; EC=2.7.11.1; AltName: Full=Ataxia telangiectasia and Rad3-related protein; AltName: Full=FRAP-related protein 1;"]
[5452,"'POU2F2'",33,29,31,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00511///Short rib-polydactyly syndrome+++H02157///Short-rib thoracic dysplasia",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0019904///protein domain specific binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding","GO:0048305///immunoglobulin secretion+++GO:0002380///immunoglobulin secretion involved in immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0048469///cell maturation+++GO:0006366///transcription by RNA polymerase II+++GO:0006959///humoral immune response+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0002335///mature B cell differentiation","IPR001356///Homeobox domain+++IPR010982///Lambda repressor-like, DNA-binding domain superfamily+++IPR013847///POU domain+++IPR017970///Homeobox, conserved site+++IPR000972///Octamer-binding transcription factor+++IPR000327///POU-specific domain+++IPR009057///Homeobox-like domain superfamily","[PO2F2_HUMAN|Reviewed]RecName: Full=POU domain, class 2, transcription factor 2; AltName: Full=Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; AltName: Full=Octamer-binding protein 2; Short=Oct-2; AltName: Full=Octamer-binding transcription factor 2; Short=OTF-2;+++[A0A024R0L3_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[A0A0D9SF23_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000486228};+++[A0A1B0GUT9_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000490243}; Flags: Fragment;+++[A0A1B0GV81_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000490407}; Flags: Fragment;+++[A0A1B0GW97_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000490838}; Flags: Fragment;+++[B5ME60_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[E9PR37_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000436100};+++[H0YKT2_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194}; Flags: Fragment;+++[H0YLL6_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[H0YNG1_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000453995}; Flags: Fragment;+++[H0YNW1_HUMAN|Unreviewed]RecName: Full=POU domain protein {ECO:0000256|RuleBase:RU361194};+++[M0R1I6_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000471890}; Flags: Fragment;+++[U3KQ96_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000475664}; Flags: Fragment;+++[U3KQN1_HUMAN|Unreviewed]SubName: Full=POU domain, class 2, transcription factor 2 {ECO:0000313|Ensembl:ENSP00000476062}; Flags: Fragment;"]
[54541,"'DDIT4'",842,761,801.5,"04150///mTOR signaling pathway+++04140///Autophagy - animal+++04151///PI3K-Akt signaling pathway+++05206///MicroRNAs in cancer",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005622///intracellular+++GO:0005739///mitochondrion","GO:0071889///14-3-3 protein binding","GO:0008283///cell proliferation+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:1901216///positive regulation of neuron death+++GO:0032984///protein-containing complex disassembly+++GO:0030182///neuron differentiation+++GO:0001666///response to hypoxia+++GO:0009968///negative regulation of signal transduction+++GO:1902532///negative regulation of intracellular signal transduction+++GO:0001764///neuron migration+++GO:0032007///negative regulation of TOR signaling+++GO:0045820///negative regulation of glycolytic process+++GO:0006915///apoptotic process+++GO:0051607///defense response to virus+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0072593///reactive oxygen species metabolic process+++GO:0007420///brain development+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0071549///cellular response to dexamethasone stimulus","IPR038281///RTP801-like, C-terminal domain superfamily+++IPR012918///RTP801-like","[DDIT4_HUMAN|Reviewed]RecName: Full=DNA damage-inducible transcript 4 protein; AltName: Full=HIF-1 responsive protein RTP801; AltName: Full=Protein regulated in development and DNA damage response 1; Short=REDD-1;+++[A0A024QZQ6_HUMAN|Unreviewed]SubName: Full=DNA-damage-inducible transcript 4, isoform CRA_a {ECO:0000313|EMBL:EAW54453.1};"]
[54542,"'RC3H2'",408,580,494,{"$nulls":4},"GO:0016020///membrane+++GO:0009986///cell surface+++GO:0000932///P-body+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm","GO:0003729///mRNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0035613///RNA stem-loop binding+++GO:0016740///transferase activity+++GO:0003677///DNA binding+++GO:0003725///double-stranded RNA binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0003723///RNA binding+++GO:0046872///metal ion binding","GO:0000209///protein polyubiquitination+++GO:0050852///T cell receptor signaling pathway+++GO:0009791///post-embryonic development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010608///posttranscriptional regulation of gene expression+++GO:2000628///regulation of miRNA metabolic process+++GO:0016567///protein ubiquitination+++GO:0061470///T follicular helper cell differentiation+++GO:0042098///T cell proliferation+++GO:0048286///lung alveolus development+++GO:0048535///lymph node development+++GO:0048536///spleen development+++GO:0060173///limb development+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:2000320///negative regulation of T-helper 17 cell differentiation+++GO:0010468///regulation of gene expression+++GO:0035264///multicellular organism growth+++GO:0043029///T cell homeostasis+++GO:0001782///B cell homeostasis","IPR017907///Zinc finger, RING-type, conserved site+++IPR032670///Roquin-2+++IPR027370///RING-type zinc-finger, LisH dimerisation motif+++IPR000571///Zinc finger, CCCH-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR036855///Zinc finger, CCCH-type superfamily","[RC3H2_HUMAN|Reviewed]RecName: Full=Roquin-2; EC=2.3.2.27 {ECO:0000269|PubMed:26249698}; AltName: Full=Membrane-associated nucleic acid-binding protein; AltName: Full=RING finger and CCCH-type zinc finger domain-containing protein 2; AltName: Full=RING finger protein 164; AltName: Full=RING-type E3 ubiquitin transferase Roquin-2 {ECO:0000305};+++[A0A024R899_HUMAN|Unreviewed]SubName: Full=Membrane associated DNA binding protein, isoform CRA_a {ECO:0000313|EMBL:EAW87550.1};+++[A6NHN2_HUMAN|Unreviewed]SubName: Full=Roquin-2 {ECO:0000313|Ensembl:ENSP00000335150};+++[H0Y5D9_HUMAN|Unreviewed]SubName: Full=Roquin-2 {ECO:0000313|Ensembl:ENSP00000398081}; Flags: Fragment;+++[Q4VXB2_HUMAN|Unreviewed]SubName: Full=Roquin-2 {ECO:0000313|Ensembl:ENSP00000381663}; Flags: Fragment;"]
[5457,"'POU4F1'",1,0,0.5,null,"H00604///Deafness, autosomal dominant",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm","GO:0003682///chromatin binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0051020///GTPase binding+++GO:0003677///DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003697///single-stranded DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003714///transcription corepressor activity","GO:0007399///nervous system development+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071345///cellular response to cytokine stimulus+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0071392///cellular response to estradiol stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0021535///cell migration in hindbrain+++GO:0043069///negative regulation of programmed cell death+++GO:0021559///trigeminal nerve development+++GO:0001967///suckling behavior+++GO:0007416///synapse assembly+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0060384///innervation+++GO:0021953///central nervous system neuron differentiation+++GO:0021986///habenula development+++GO:0071158///positive regulation of cell cycle arrest+++GO:0048934///peripheral nervous system neuron differentiation+++GO:0007409///axonogenesis+++GO:0010629///negative regulation of gene expression+++GO:0043065///positive regulation of apoptotic process+++GO:2001208///negative regulation of transcription elongation by RNA polymerase I+++GO:0030182///neuron differentiation+++GO:0031175///neuron projection development+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0051090///regulation of DNA-binding transcription factor activity+++GO:0043066///negative regulation of apoptotic process+++GO:0051355///proprioception involved in equilibrioception+++GO:0007275///multicellular organism development+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0007507///heart development+++GO:0050767///regulation of neurogenesis+++GO:0048665///neuron fate specification+++GO:0048935///peripheral nervous system neuron development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048880///sensory system development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0010628///positive regulation of gene expression+++GO:0007498///mesoderm development","IPR017970///Homeobox, conserved site+++IPR001387///Cro/C1-type helix-turn-helix domain+++IPR015584///POU domain, class 4, transcription factor 1+++IPR009057///Homeobox-like domain superfamily+++IPR001356///Homeobox domain+++IPR010982///Lambda repressor-like, DNA-binding domain superfamily+++IPR013847///POU domain+++IPR000327///POU-specific domain","[PO4F1_HUMAN|Reviewed]RecName: Full=POU domain, class 4, transcription factor 1 {ECO:0000312|HGNC:HGNC:9218}; AltName: Full=Brain-specific homeobox/POU domain protein 3A; Short=Brain-3A; Short=Brn-3A; AltName: Full=Homeobox/POU domain protein RDC-1; AltName: Full=Oct-T1;"]
[54626,"'HES2'",151,162,156.5,"05165///Human papillomavirus infection","H00517///Spondylocostal dysostosis (SCD)",null,null,"GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0046983///protein dimerization activity+++GO:0003714///transcription corepressor activity+++GO:0003690///double-stranded DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0001756///somitogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007219///Notch signaling pathway+++GO:0030154///cell differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0050767///regulation of neurogenesis","IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain+++IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR003650///Orange domain","[HES2_HUMAN|Reviewed]RecName: Full=Transcription factor HES-2; AltName: Full=Class B basic helix-loop-helix protein 40; Short=bHLHb40; AltName: Full=Hairy and enhancer of split 2;+++[K7EJN2_HUMAN|Unreviewed]SubName: Full=Transcription factor HES-2 {ECO:0000313|Ensembl:ENSP00000465248};+++[K7EJQ0_HUMAN|Unreviewed]SubName: Full=Transcription factor HES-2 {ECO:0000313|Ensembl:ENSP00000465270};"]
[5467,"'PPARD'",643,740,691.5,"05200///Pathways in cancer+++05221///Acute myeloid leukemia+++04310///Wnt signaling pathway+++03320///PPAR signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0003707///steroid hormone receptor activity+++GO:0008289///lipid binding+++GO:0008134///transcription factor binding+++GO:0008144///drug binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005504///fatty acid binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0005515///protein binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0051059///NF-kappaB binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity+++GO:0046872///metal ion binding+++GO:0070539///linoleic acid binding+++GO:0003713///transcription coactivator activity+++GO:0004879///nuclear receptor activity+++GO:0001103///RNA polymerase II repressing transcription factor binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0038023///signaling receptor activity","GO:0006631///fatty acid metabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0097190///apoptotic signaling pathway+++GO:0042060///wound healing+++GO:0008654///phospholipid biosynthetic process+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0031589///cell-substrate adhesion+++GO:0019216///regulation of lipid metabolic process+++GO:0008283///cell proliferation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0033189///response to vitamin A+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0043066///negative regulation of apoptotic process+++GO:0043401///steroid hormone mediated signaling pathway+++GO:0043415///positive regulation of skeletal muscle tissue regeneration+++GO:0008284///positive regulation of cell proliferation+++GO:1904659///glucose transmembrane transport+++GO:0009755///hormone-mediated signaling pathway+++GO:0007507///heart development+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0007275///multicellular organism development+++GO:0009062///fatty acid catabolic process+++GO:0045598///regulation of fat cell differentiation+++GO:0006091///generation of precursor metabolites and energy+++GO:0046697///decidualization+++GO:0010628///positive regulation of gene expression+++GO:0006629///lipid metabolic process+++GO:0033993///response to lipid+++GO:0032966///negative regulation of collagen biosynthetic process+++GO:2000288///positive regulation of myoblast proliferation+++GO:0006635///fatty acid beta-oxidation+++GO:0009299///mRNA transcription+++GO:0009749///response to glucose+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0050728///negative regulation of inflammatory response+++GO:0030522///intracellular receptor signaling pathway+++GO:0043616///keratinocyte proliferation+++GO:0030308///negative regulation of cell growth+++GO:0045600///positive regulation of fat cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0014823///response to activity+++GO:0071222///cellular response to lipopolysaccharide+++GO:0014842///regulation of skeletal muscle satellite cell proliferation+++GO:0045662///negative regulation of myoblast differentiation+++GO:0007566///embryo implantation+++GO:0045684///positive regulation of epidermis development+++GO:0006776///vitamin A metabolic process+++GO:0060612///adipose tissue development+++GO:0010033///response to organic substance+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0008366///axon ensheathment+++GO:0006915///apoptotic process+++GO:0097755///positive regulation of blood vessel diameter+++GO:0001890///placenta development+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0010887///negative regulation of cholesterol storage+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0015908///fatty acid transport+++GO:0008203///cholesterol metabolic process+++GO:0019395///fatty acid oxidation+++GO:0042127///regulation of cell proliferation+++GO:0051546///keratinocyte migration+++GO:0032024///positive regulation of insulin secretion+++GO:0030154///cell differentiation+++GO:0006029///proteoglycan metabolic process+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0071456///cellular response to hypoxia+++GO:0006006///glucose metabolic process","IPR013088///Zinc finger, NHR/GATA-type+++IPR003075///Peroxisome proliferator-activated receptor, beta+++IPR001723///Nuclear hormone receptor+++IPR000536///Nuclear hormone receptor, ligand-binding domain+++IPR001628///Zinc finger, nuclear hormone receptor-type+++IPR035500///Nuclear hormone receptor-like domain superfamily+++IPR003074///Peroxisome proliferator-activated receptor","[PPARD_HUMAN|Reviewed]RecName: Full=Peroxisome proliferator-activated receptor delta; Short=PPAR-delta; AltName: Full=NUCI; AltName: Full=Nuclear hormone receptor 1; Short=NUC1; AltName: Full=Nuclear receptor subfamily 1 group C member 2; AltName: Full=Peroxisome proliferator-activated receptor beta; Short=PPAR-beta;+++[A0A024RCW6_HUMAN|Unreviewed]SubName: Full=Peroxisome proliferative activated receptor, delta, isoform CRA_a {ECO:0000313|EMBL:EAX03827.1};+++[F1D8S7_HUMAN|Unreviewed]SubName: Full=Peroxisome proliferative activated receptor, delta, isoform CRA_b {ECO:0000313|EMBL:EAX03826.1}; SubName: Full=Peroxisome proliferator-activated nuclear receptor beta/delta variant 2 {ECO:0000313|EMBL:ADZ17376.1};+++[L8EBG7_HUMAN|Unreviewed]SubName: Full=Alternative protein PPARD {ECO:0000313|EMBL:CCQ43908.1};"]
[54708,"'MARCH5'",431,460,445.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0005741///mitochondrial outer membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum","GO:0016740///transferase activity+++GO:0051020///GTPase binding+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0090140///regulation of mitochondrial fission+++GO:0051865///protein autoubiquitination+++GO:0090344///negative regulation of cell aging+++GO:0090141///positive regulation of mitochondrial fission+++GO:0070585///protein localization to mitochondrion+++GO:0000209///protein polyubiquitination","IPR033275///E3 ubiquitin-protein ligase MARCH-like+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR011016///Zinc finger, RING-CH-type","[MARH5_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase MARCH5; EC=2.3.2.27; AltName: Full=Membrane-associated RING finger protein 5; AltName: Full=Membrane-associated RING-CH protein V; Short=MARCH-V; AltName: Full=Mitochondrial ubiquitin ligase; Short=MITOL; AltName: Full=RING finger protein 153; AltName: Full=RING-type E3 ubiquitin transferase MARCH5 {ECO:0000305};"]
[54756,"'IL17RD'",1512.03,1904.02,1708.025,null,"H00255///Hypogonadotropic hypogonadism",null,null,"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane","GO:0030368///interleukin-17 receptor activity","GO:0000165///MAPK cascade+++GO:0019221///cytokine-mediated signaling pathway","IPR035897///Toll/interleukin-1 receptor homology (TIR) domain superfamily+++IPR039465///Interleukin-17 receptor-like+++IPR031951///Interleukin 17 receptor D, N-terminal+++IPR013568///SEFIR domain","[I17RD_HUMAN|Reviewed]RecName: Full=Interleukin-17 receptor D; Short=IL-17 receptor D; Short=IL-17RD; AltName: Full=IL17Rhom; AltName: Full=Interleukin-17 receptor-like protein; AltName: Full=Sef homolog; Short=hSef; Flags: Precursor;+++[B4DXM5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50280, highly similar to Interleukin-17 receptor D {ECO:0000313|EMBL:BAG63437.1};+++[C9J6R0_HUMAN|Unreviewed]SubName: Full=Interleukin-17 receptor D {ECO:0000313|Ensembl:ENSP00000418368}; Flags: Fragment;"]
[54780,"'NSMCE4A'",138,121,129.5,{"$nulls":4},"GO:0030915///Smc5-Smc6 complex+++GO:0005654///nucleoplasm+++GO:0000781///chromosome, telomeric region+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0016604///nuclear body","GO:0005515///protein binding","GO:0006281///DNA repair+++GO:0006310///DNA recombination+++GO:2001022///positive regulation of response to DNA damage stimulus+++GO:0006974///cellular response to DNA damage stimulus","IPR029225///Nse4/EID protein, Nse3/MAGE-binding domain+++IPR027786///Nse4/EID family+++IPR014854///Non-structural maintenance of chromosome element 4, C-terminal","[NSE4A_HUMAN|Reviewed]RecName: Full=Non-structural maintenance of chromosomes element 4 homolog A; Short=NS4EA; Short=Non-SMC element 4 homolog A;"]
[54802,"'TRIT1'",156,142,149,"01110///Biosynthesis of secondary metabolites+++00908///Zeatin biosynthesis+++01100///Metabolic pathways",null,null,"R01122///delta2-isopentenyl-diphosphate:tRNA isopentenyltransferase   Dimethylallyl diphosphate + tRNA <=> Diphosphate + tRNA containing 6-isopentenyladenosine","GO:0005759///mitochondrial matrix+++GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm","GO:0052381///tRNA dimethylallyltransferase activity+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0008270///zinc ion binding+++GO:0003676///nucleic acid binding","GO:0070900///mitochondrial tRNA modification+++GO:0008033///tRNA processing+++GO:0006400///tRNA modification","IPR030666///tRNA isopentenyltransferase, eukaryotes+++IPR036236///Zinc finger C2H2 superfamily+++IPR003604///Matrin/U1-C-like, C2H2-type zinc finger+++IPR022755///Zinc finger, double-stranded RNA binding+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR039657///Dimethylallyltransferase+++IPR018022///IPP transferase","[MOD5_HUMAN|Reviewed]RecName: Full=tRNA dimethylallyltransferase; EC=2.5.1.75 {ECO:0000269|PubMed:24901367}; AltName: Full=Isopentenyl-diphosphate:tRNA isopentenyltransferase; Short=IPP transferase; Short=IPPT; AltName: Full=hGRO1; AltName: Full=tRNA isopentenyltransferase 1; Short=IPTase; Flags: Precursor;+++[B4DK89_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60623, highly similar to tRNA isopentenyltransferase, mitochondrial {ECO:0000313|EMBL:BAG59101.1}; SubName: Full=tRNA dimethylallyltransferase {ECO:0000313|Ensembl:ENSP00000473745};+++[I6L9K0_HUMAN|Unreviewed]SubName: Full=TRIT1 protein {ECO:0000313|EMBL:AAI28157.1};+++[Q3T7B4_HUMAN|Unreviewed]SubName: Full=tRNA dimethylallyltransferase {ECO:0000313|Ensembl:ENSP00000437896}; SubName: Full=tRNA isopentenylpyrophosphate transferase isoform 7 {ECO:0000313|EMBL:AAW63407.1};+++[Q3T7B8_HUMAN|Unreviewed]SubName: Full=tRNA isopentenylpyrophosphate transferase isoform 5 {ECO:0000313|EMBL:AAW63403.1};+++[Q3T7C3_HUMAN|Unreviewed]SubName: Full=tRNA isopentenylpyrophosphate transferase isoform 4 {ECO:0000313|EMBL:AAW63398.1};+++[Q3T7C5_HUMAN|Unreviewed]SubName: Full=tRNA isopentenylpyrophosphate transferase isoform 3 {ECO:0000313|EMBL:AAW63396.1};+++[Q3T7C6_HUMAN|Unreviewed]SubName: Full=tRNA isopentenylpyrophosphate transferase isoform 2 {ECO:0000313|EMBL:AAW63395.1};+++[Q3T7C7_HUMAN|Unreviewed]SubName: Full=tRNA isopentenylpyrophosphate transferase isoform 1 {ECO:0000313|EMBL:AAW63394.1}; EC=2.5.1.8 {ECO:0000313|EMBL:AAW63394.1};+++[Q53F11_HUMAN|Unreviewed]SubName: Full=tRNA isopentenyltransferase 1 variant {ECO:0000313|EMBL:BAD97198.1}; Flags: Fragment;+++[S4R2X1_HUMAN|Unreviewed]SubName: Full=tRNA dimethylallyltransferase {ECO:0000313|Ensembl:ENSP00000473708}; Flags: Fragment;+++[S4R2Z0_HUMAN|Unreviewed]SubName: Full=tRNA dimethylallyltransferase {ECO:0000313|Ensembl:ENSP00000473773};+++[S4R3C5_HUMAN|Unreviewed]SubName: Full=tRNA dimethylallyltransferase {ECO:0000313|Ensembl:ENSP00000474151}; Flags: Fragment;+++[S4R3F4_HUMAN|Unreviewed]SubName: Full=tRNA dimethylallyltransferase {ECO:0000313|Ensembl:ENSP00000474264};+++[S4R3U8_HUMAN|Unreviewed]SubName: Full=tRNA dimethylallyltransferase {ECO:0000313|Ensembl:ENSP00000474768}; Flags: Fragment;"]
[54822,"'TRPM7'",288,397,342.5,"04218///Cellular senescence+++04621///NOD-like receptor signaling pathway+++04217///Necroptosis+++04978///Mineral absorption","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0016020///membrane+++GO:0005623///cell+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0001726///ruffle","GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0005216///ion channel activity+++GO:0046872///metal ion binding+++GO:0017022///myosin binding+++GO:0003779///actin binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005262///calcium channel activity","GO:0010961///cellular magnesium ion homeostasis+++GO:0006468///protein phosphorylation+++GO:0055085///transmembrane transport+++GO:0031032///actomyosin structure organization+++GO:0006816///calcium ion transport+++GO:0070266///necroptotic process+++GO:0070588///calcium ion transmembrane transport+++GO:0046777///protein autophosphorylation+++GO:0016310///phosphorylation+++GO:0012501///programmed cell death+++GO:0006811///ion transport+++GO:0006812///cation transport+++GO:0016340///calcium-dependent cell-matrix adhesion+++GO:0034220///ion transmembrane transport+++GO:0051262///protein tetramerization","IPR037162///TRPM, tetramerisation domain superfamily+++IPR004166///MHCK/EF2 kinase+++IPR029601///Transient receptor potential cation channel subfamily M member 7+++IPR032415///TRPM, tetramerisation domain+++IPR005821///Ion transport domain+++IPR011009///Protein kinase-like domain superfamily","[TRPM7_HUMAN|Reviewed]RecName: Full=Transient receptor potential cation channel subfamily M member 7; EC=2.7.11.1; AltName: Full=Channel-kinase 1; AltName: Full=Long transient receptor potential channel 7; Short=LTrpC-7; Short=LTrpC7;+++[A0A024R5V1_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel, subfamily M, member 7, isoform CRA_a {ECO:0000313|EMBL:EAW77408.1};+++[A0A0C4DGL2_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily M member 7 {ECO:0000313|Ensembl:ENSP00000452873}; Flags: Fragment;+++[H0YLN8_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily M member 7 {ECO:0000313|Ensembl:ENSP00000453277}; SubName: Full=Transient receptor potential cation channel, subfamily M, member 7, isoform CRA_c {ECO:0000313|EMBL:EAW77407.1};+++[H0YNM0_HUMAN|Unreviewed]SubName: Full=Transient receptor potential cation channel subfamily M member 7 {ECO:0000313|Ensembl:ENSP00000454066}; Flags: Fragment;"]
[54842,"'MFSD6'",414,468.27,441.135,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","IPR024989///Major facilitator superfamily associated domain+++IPR020846///Major facilitator superfamily domain+++IPR036259///MFS transporter superfamily","[MFSD6_HUMAN|Reviewed]RecName: Full=Major facilitator superfamily domain-containing protein 6; AltName: Full=Macrophage MHC class I receptor 2 homolog;+++[C9IYL1_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000406837}; Flags: Fragment;+++[C9J134_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000400131}; Flags: Fragment;+++[C9JAZ7_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000398737}; Flags: Fragment;+++[C9JJH2_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000403762}; Flags: Fragment;+++[H7C0X2_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000397276}; Flags: Fragment;+++[H7C284_HUMAN|Unreviewed]SubName: Full=Major facilitator superfamily domain-containing protein 6 {ECO:0000313|Ensembl:ENSP00000404511}; Flags: Fragment;"]
[54861,"'SNRK'",130,149,139.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0000287///magnesium ion binding+++GO:0004672///protein kinase activity","GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0030099///myeloid cell differentiation","IPR015940///Ubiquitin-associated domain+++IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site","[SNRK_HUMAN|Reviewed]RecName: Full=SNF-related serine/threonine-protein kinase; EC=2.7.11.1; AltName: Full=SNF1-related kinase;+++[A0A024R2Y6_HUMAN|Unreviewed]SubName: Full=SNF related kinase, isoform CRA_a {ECO:0000313|EMBL:EAW64694.1};+++[A8K5P5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77864, highly similar to Homo sapiens HSNFRK (HSNFRK) mRNA {ECO:0000313|EMBL:BAF84049.1};+++[B4DHM9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59517, highly similar to SNF-related serine/threonine-protein kinase {ECO:0000313|EMBL:BAG58191.1};+++[E7EUC4_HUMAN|Unreviewed]SubName: Full=SNF-related serine/threonine-protein kinase {ECO:0000313|Ensembl:ENSP00000409516};"]
[54877,"'ZCCHC2'",121,239,180,{"$nulls":4},"GO:0005737///cytoplasm","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0035091///phosphatidylinositol binding",null,"IPR036871///PX domain superfamily+++IPR001878///Zinc finger, CCHC-type+++IPR036875///Zinc finger, CCHC-type superfamily","[ZCHC2_HUMAN|Reviewed]RecName: Full=Zinc finger CCHC domain-containing protein 2;+++[A0A087WXC7_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000480901}; Flags: Fragment;+++[K7EKB8_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000465548}; Flags: Fragment;+++[K7ERQ9_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000468368}; Flags: Fragment;+++[K7ESN2_HUMAN|Unreviewed]SubName: Full=Zinc finger CCHC domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000468789}; Flags: Fragment;+++[Q9BRD4_HUMAN|Unreviewed]SubName: Full=ZCCHC2 protein {ECO:0000313|EMBL:AAH06340.1}; SubName: Full=Zinc finger, CCHC domain containing 2, isoform CRA_c {ECO:0000313|EMBL:EAW63128.1};"]
[54893,"'MTMR10'",205,227,216,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm",null,null,"IPR022587///Myotubularin-related 12-like C-terminal domain+++IPR030573///Myotubularin-related protein 10+++IPR036004///MTMR10, PH-GRAM domain+++IPR010569///Myotubularin-like phosphatase domain+++IPR030564///Myotubularin family+++IPR029021///Protein-tyrosine phosphatase-like","[MTMRA_HUMAN|Reviewed]RecName: Full=Myotubularin-related protein 10;+++[A0A024R211_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10, isoform CRA_a {ECO:0000313|EMBL:EAW61259.1};+++[H3BQP4_HUMAN|Unreviewed]SubName: Full=Myotubularin-related protein 10 {ECO:0000313|Ensembl:ENSP00000455869}; Flags: Fragment;+++[H3BQR5_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform E {ECO:0000313|EMBL:AHW56722.1}; SubName: Full=Myotubularin-related protein 10 {ECO:0000313|Ensembl:ENSP00000455903};+++[H3BUS9_HUMAN|Unreviewed]SubName: Full=Myotubularin-related protein 10 {ECO:0000313|Ensembl:ENSP00000457781};+++[H3BUZ0_HUMAN|Unreviewed]SubName: Full=Myotubularin-related protein 10 {ECO:0000313|Ensembl:ENSP00000457873}; Flags: Fragment;+++[Q0IJ45_HUMAN|Unreviewed]SubName: Full=MTMR10 protein {ECO:0000313|EMBL:AAI21173.1}; Flags: Fragment;+++[Q0IJ46_HUMAN|Unreviewed]SubName: Full=MTMR10 protein {ECO:0000313|EMBL:AAI21172.1}; Flags: Fragment;+++[X5D300_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform A {ECO:0000313|EMBL:AHW56669.1};+++[X5D334_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform B {ECO:0000313|EMBL:AHW56714.1};+++[X5D7X7_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform D {ECO:0000313|EMBL:AHW56710.1};+++[X5D963_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform C {ECO:0000313|EMBL:AHW56523.1}; Flags: Fragment;+++[X5DP53_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform F {ECO:0000313|EMBL:AHW56651.1};+++[X5DR33_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform G {ECO:0000313|EMBL:AHW56522.1}; Flags: Fragment;+++[X5DRD0_HUMAN|Unreviewed]SubName: Full=Myotubularin related protein 10 isoform H {ECO:0000313|EMBL:AHW56627.1};"]
[54914,"'FOCAD'",334,444,389,"01110///Biosynthesis of secondary metabolites+++00062///Fatty acid elongation+++04140///Autophagy - animal+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism+++04137///Mitophagy - animal",null,"M00415///Fatty acid biosynthesis, elongation, endoplasmic reticulum","R10827///very-long-chain (3R)-3-hydroxyacyl-CoA hydro-lyase Very-long-chain (3R)-3-hydroxyacyl-CoA <=> Very-long-chain trans-2,3-dehydroacyl-CoA + H2O+++R07760///3-Hydroxyoctadecanoyl-CoA <=> (2E)-Octadecenoyl-CoA + H2O","GO:0030054///cell junction+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis","IPR022542///Domain of unknown function DUF3730+++IPR016024///Armadillo-type fold+++IPR021392///Focadhesin","[FOCAD_HUMAN|Reviewed]RecName: Full=Focadhesin;+++[B3KNV9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30554 fis, clone BRAWH2003693 {ECO:0000313|EMBL:BAG51471.1};+++[S4R3N8_HUMAN|Unreviewed]SubName: Full=Focadhesin {ECO:0000313|Ensembl:ENSP00000474563}; Flags: Fragment;+++[S4R3S9_HUMAN|Unreviewed]SubName: Full=Focadhesin {ECO:0000313|Ensembl:ENSP00000474683}; Flags: Fragment;+++[S4R400_HUMAN|Unreviewed]SubName: Full=Focadhesin {ECO:0000313|Ensembl:ENSP00000474915};+++[S4R437_HUMAN|Unreviewed]SubName: Full=Focadhesin {ECO:0000313|Ensembl:ENSP00000475030};+++[S4R450_HUMAN|Unreviewed]SubName: Full=Focadhesin {ECO:0000313|Ensembl:ENSP00000475075}; Flags: Fragment;"]
[54930,"'HAUS4'",72,78,75,{"$nulls":4},"GO:0005819///spindle+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0070652///HAUS complex+++GO:0005813///centrosome+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0007098///centrosome cycle+++GO:0051225///spindle assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0000086///G2/M transition of mitotic cell cycle","IPR026214///HAUS augmin-like complex subunit 4, metazoa+++IPR029327///HAUS augmin-like complex subunit 4","[HAUS4_HUMAN|Reviewed]RecName: Full=HAUS augmin-like complex subunit 4;+++[G3V2I5_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450680}; Flags: Fragment;+++[G3V4X7_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452058}; Flags: Fragment;+++[G3V541_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452165}; Flags: Fragment;+++[G3V5A5_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452261}; Flags: Fragment;+++[G3V5Z2_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000452595}; Flags: Fragment;+++[H0YIZ6_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450542}; Flags: Fragment;+++[H0YJ09_HUMAN|Unreviewed]SubName: Full=HAUS augmin-like complex subunit 4 {ECO:0000313|Ensembl:ENSP00000450612}; Flags: Fragment;"]
[54947,"'LPCAT2'",1972,1707,1839.5,"01100///Metabolic pathways+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism","H00472///Multicentric osteolysis, nodulosis, and arthropathy (MONA)+++H00028///Choriocarcinoma+++H00025///Penile cancer",null,"R09036///acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol+++R03437///Acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase   Acetyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R03438///Acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 1-Radyl-2-acyl-sn-glycero-3-phosphocholine","GO:0005789///endoplasmic reticulum membrane+++GO:0005794///Golgi apparatus+++GO:0005783///endoplasmic reticulum+++GO:0005795///Golgi stack+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005811///lipid droplet+++GO:0000139///Golgi membrane","GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047192///1-alkylglycerophosphocholine O-acetyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity","GO:0006644///phospholipid metabolic process+++GO:0006629///lipid metabolic process+++GO:0008654///phospholipid biosynthetic process+++GO:0061024///membrane organization+++GO:0006663///platelet activating factor biosynthetic process+++GO:0036151///phosphatidylcholine acyl-chain remodeling","IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain+++IPR018247///EF-Hand 1, calcium-binding site+++IPR002123///Phospholipid/glycerol acyltransferase","[PCAT2_HUMAN|Reviewed]RecName: Full=Lysophosphatidylcholine acyltransferase 2; Short=LPC acyltransferase 2; Short=LPCAT-2; Short=LysoPC acyltransferase 2; EC=2.3.1.23; AltName: Full=1-acylglycerol-3-phosphate O-acyltransferase 11; Short=1-AGP acyltransferase 11; Short=1-AGPAT 11; EC=2.3.1.51; AltName: Full=1-acylglycerophosphocholine O-acyltransferase; AltName: Full=1-alkylglycerophosphocholine O-acetyltransferase; EC=2.3.1.67; AltName: Full=Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; Short=Acetyl-CoA:lyso-PAF acetyltransferase; Short=Lyso-PAF acetyltransferase; Short=LysoPAFAT; AltName: Full=Acyltransferase-like 1; AltName: Full=Lysophosphatidic acid acyltransferase alpha; Short=LPAAT-alpha;+++[H3BU68_HUMAN|Unreviewed]SubName: Full=Lysophosphatidylcholine acyltransferase 2 {ECO:0000313|Ensembl:ENSP00000457496}; Flags: Fragment;"]
[54961,"'SSH3'",817,677,747,"04360///Axon guidance+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005856///cytoskeleton","GO:0016787///hydrolase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0003779///actin binding+++GO:0016791///phosphatase activity","GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0010591///regulation of lamellipodium assembly+++GO:0008064///regulation of actin polymerization or depolymerization+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0050770///regulation of axonogenesis","IPR016130///Protein-tyrosine phosphatase, active site+++IPR014876///DEK, C-terminal+++IPR000387///Tyrosine specific protein phosphatases domain+++IPR000340///Dual specificity phosphatase, catalytic domain+++IPR029021///Protein-tyrosine phosphatase-like+++IPR020422///Dual specificity protein phosphatase domain+++IPR024950///Dual specificity phosphatase","[SSH3_HUMAN|Reviewed]RecName: Full=Protein phosphatase Slingshot homolog 3; EC=3.1.3.16; EC=3.1.3.48; AltName: Full=SSH-like protein 3; Short=SSH-3L; Short=hSSH-3L;+++[A0A024R5C3_HUMAN|Unreviewed]SubName: Full=Slingshot homolog 3 (Drosophila), isoform CRA_g {ECO:0000313|EMBL:EAW74596.1};+++[A0A024R5J4_HUMAN|Unreviewed]SubName: Full=Slingshot homolog 3 (Drosophila), isoform CRA_f {ECO:0000313|EMBL:EAW74594.1};+++[A0A087WWG1_HUMAN|Unreviewed]SubName: Full=Protein phosphatase Slingshot homolog 3 {ECO:0000313|Ensembl:ENSP00000480198}; Flags: Fragment;+++[C9JUG3_HUMAN|Unreviewed]SubName: Full=Protein phosphatase Slingshot homolog 3 {ECO:0000313|Ensembl:ENSP00000310055}; SubName: Full=Slingshot homolog 3 (Drosophila), isoform CRA_e {ECO:0000313|EMBL:EAW74591.1};+++[E9PIT5_HUMAN|Unreviewed]SubName: Full=Protein phosphatase Slingshot homolog 3 {ECO:0000313|Ensembl:ENSP00000433902}; Flags: Fragment;+++[E9PMS1_HUMAN|Unreviewed]SubName: Full=Protein phosphatase Slingshot homolog 3 {ECO:0000313|Ensembl:ENSP00000432974};+++[L8EA09_HUMAN|Unreviewed]SubName: Full=Alternative protein SSH3 {ECO:0000313|EMBL:CCQ43576.1};"]
[54978,"'SLC35F6'",891,878,884.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion","GO:0005515///protein binding+++GO:0022857///transmembrane transporter activity","GO:0008284///positive regulation of cell proliferation+++GO:0055085///transmembrane transport+++GO:1901029///negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","IPR012404///Nucleotide-sugar transporter-related+++IPR009262///Solute carrier family 35 member SLC35F1/F2/F6","[S35F6_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member F6; AltName: Full=ANT2-binding protein; Short=ANT2BP; AltName: Full=Transport and Golgi organization 9 homolog; Flags: Precursor;+++[B4DLH2_HUMAN|Unreviewed]SubName: Full=Chromosome 2 open reading frame 18, isoform CRA_c {ECO:0000313|EMBL:EAX00675.1}; SubName: Full=cDNA FLJ55094 {ECO:0000313|EMBL:BAG59534.1};+++[F8WB19_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member F6 {ECO:0000313|Ensembl:ENSP00000397623};+++[F8WCT7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 35 member F6 {ECO:0000313|Ensembl:ENSP00000396256};"]
[54995,"'OXSM'",69,48,58.5,"01100///Metabolic pathways+++01212///Fatty acid metabolism+++00780///Biotin metabolism+++00061///Fatty acid biosynthesis","H00118///Congenital disorders of glycosylation (CDG) type I","M00572///Pimeloyl-ACP biosynthesis, BioC-BioH pathway, malonyl-ACP => pimeloyl-ACP+++M00083///Fatty acid biosynthesis, elongation","R04968///Tetradecanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexadecanoyl-[acp] + CO2 + Acyl-carrier protein+++R04726///dodecanoyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Dodecanoyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> 3-Oxotetradecanoyl-[acp] + CO2 + Acyl-carrier protein+++R10115///malonyl-[acyl-carrier protein]-methyl-ester:malonyl-[acyl-carrier protein]  C-acyltransferase   Malonyl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketoglutaryl-[acp] methyl ester + CO2 + Acyl-carrier protein+++R04957///hexanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxooctanoyl-[acp] + CO2 + Acyl-carrier protein+++R10119///glutaryl-[acp]-methyl-ester:malonyl-[acyl-carrier protein] C-acyltransferase (decarboxylating)   Glutaryl-[acp] methyl ester + Malonyl-[acyl-carrier protein] <=> 3-Ketopimeloyl-[acp] methyl ester + CO2 + Acyl-carrier protein+++R04960///Octanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Octanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxodecanoyl-[acp] + CO2 + Acyl-carrier protein+++R04952///butyryl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Butyryl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxohexanoyl-[acp] + CO2 + Acyl-carrier protein+++R04963///Decanoyl-[acyl-carrier protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Decanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxododecanoyl-[acp] + CO2 + Acyl-carrier protein+++R04355///Acyl-[acyl-carrier-protein]:malonyl-[acyl-carrier-protein] C-acyltransferase (decarboxylating)   Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CO2 + Acyl-carrier protein+++R07762///Hexadecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=> 3-Oxostearoyl-[acp] + Acyl-carrier protein + CO2","GO:0005739///mitochondrion+++GO:0005829///cytosol","GO:0016746///transferase activity, transferring acyl groups+++GO:0004315///3-oxoacyl-[acyl-carrier-protein] synthase activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0003824///catalytic activity+++GO:0016740///transferase activity","GO:0051790///short-chain fatty acid biosynthetic process+++GO:0006633///fatty acid biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0051792///medium-chain fatty acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006637///acyl-CoA metabolic process","IPR020841///Polyketide synthase, beta-ketoacyl synthase domain+++IPR014030///Beta-ketoacyl synthase, N-terminal+++IPR018201///Beta-ketoacyl synthase, active site+++IPR014031///Beta-ketoacyl synthase, C-terminal+++IPR017568///3-oxoacyl-[acyl-carrier-protein] synthase 2+++IPR016039///Thiolase-like","[OXSM_HUMAN|Reviewed]RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; EC=2.3.1.41; AltName: Full=Beta-ketoacyl-ACP synthase; Flags: Precursor;+++[A0A024R2Q9_HUMAN|Unreviewed]RecName: Full=3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial {ECO:0000256|PIRNR:PIRNR000447}; EC=2.3.1.41 {ECO:0000256|PIRNR:PIRNR000447};+++[B4E3Q7_HUMAN|Unreviewed]SubName: Full=3-oxoacyl-ACP synthase, mitochondrial, isoform CRA_a {ECO:0000313|EMBL:EAW64367.1}; SubName: Full=cDNA FLJ52134, highly similar to 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial {ECO:0000313|EMBL:BAG65569.1};+++[C9J2G3_HUMAN|Unreviewed]SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000392334}; Flags: Fragment;+++[C9JQQ2_HUMAN|Unreviewed]SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000409817}; Flags: Fragment;+++[F8VNS3_HUMAN|Unreviewed]SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial {ECO:0000313|Ensembl:ENSP00000404115};"]
[5501,"'PPP1CC'",701,763,732,"04921///Oxytocin signaling pathway+++04270///Vascular smooth muscle contraction+++03015///mRNA surveillance pathway+++05034///Alcoholism+++04390///Hippo signaling pathway+++04720///Long-term potentiation+++04910///Insulin signaling pathway+++04810///Regulation of actin cytoskeleton+++05031///Amphetamine addiction+++04510///Focal adhesion+++04611///Platelet activation+++05205///Proteoglycans in cancer+++04261///Adrenergic signaling in cardiomyocytes+++04024///cAMP signaling pathway+++05168///Herpes simplex infection+++04218///Cellular senescence+++04728///Dopaminergic synapse+++04113///Meiosis - yeast+++04022///cGMP-PKG signaling pathway+++04114///Oocyte meiosis+++04750///Inflammatory mediator regulation of TRP channels+++04931///Insulin resistance",{"$nulls":3},"GO:0005741///mitochondrial outer membrane+++GO:0000784///nuclear chromosome, telomeric region+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0000775///chromosome, centromeric region+++GO:0032154///cleavage furrow+++GO:0005730///nucleolus+++GO:0005694///chromosome+++GO:0005925///focal adhesion+++GO:0098978///glutamatergic synapse+++GO:0005739///mitochondrion+++GO:0000164///protein phosphatase type 1 complex+++GO:0098794///postsynapse+++GO:0000776///kinetochore+++GO:0043197///dendritic spine+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0000777///condensed chromosome kinetochore+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0098793///presynapse+++GO:0030496///midbody","GO:0016791///phosphatase activity+++GO:0046872///metal ion binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0003723///RNA binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0019904///protein domain specific binding+++GO:0008157///protein phosphatase 1 binding+++GO:0044877///protein-containing complex binding+++GO:0047485///protein N-terminus binding+++GO:0019901///protein kinase binding+++GO:0005521///lamin binding+++GO:0016787///hydrolase activity+++GO:0019903///protein phosphatase binding+++GO:0004722///protein serine/threonine phosphatase activity","GO:0030182///neuron differentiation+++GO:0046822///regulation of nucleocytoplasmic transport+++GO:0043153///entrainment of circadian clock by photoperiod+++GO:0007049///cell cycle+++GO:0042752///regulation of circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0005977///glycogen metabolic process+++GO:0048511///rhythmic process+++GO:0051301///cell division+++GO:0006470///protein dephosphorylation+++GO:0060252///positive regulation of glial cell proliferation+++GO:0005975///carbohydrate metabolic process","IPR029052///Metallo-dependent phosphatase-like+++IPR037981///Serine/threonine-protein phosphatase PP1-gamma catalytic subunit+++IPR004843///Calcineurin-like phosphoesterase domain, ApaH type+++IPR031675///Serine-threonine protein phosphatase, N-terminal+++IPR006186///Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase","[PP1G_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Short=PP-1G; EC=3.1.3.16; AltName: Full=Protein phosphatase 1C catalytic subunit;+++[A0A024RBP2_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[A0A087WYY5_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[F8VR82_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[F8VYE8_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[F8W0V8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase PP1-gamma catalytic subunit {ECO:0000313|Ensembl:ENSP00000447528}; Flags: Fragment;+++[F8W0W8_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[F8W1A0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase PP1-gamma catalytic subunit {ECO:0000313|Ensembl:ENSP00000447090}; Flags: Fragment;+++[Q9UPN1_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;"]
[55027,"'HEATR3'",158,155,156.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005623///cell","GO:0051082///unfolded protein binding","GO:0006606///protein import into nucleus+++GO:0042273///ribosomal large subunit biogenesis","IPR011989///Armadillo-like helical+++IPR016024///Armadillo-type fold","[HEAT3_HUMAN|Reviewed]RecName: Full=HEAT repeat-containing protein 3;"]
[55051,"'NRDE2'",154,111,132.5,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0031048///chromatin silencing by small RNA+++GO:0016246///RNA interference+++GO:0008150///biological_process","IPR013633///siRNA-mediated silencing protein NRDE-2+++IPR011990///Tetratricopeptide-like helical domain superfamily","[NRDE2_HUMAN|Reviewed]RecName: Full=Protein NRDE2 homolog;+++[A0A024R6L8_HUMAN|Unreviewed]SubName: Full=Chromosome 14 open reading frame 102, isoform CRA_c {ECO:0000313|EMBL:EAW81425.1};+++[G3V338_HUMAN|Unreviewed]SubName: Full=Protein NRDE2 homolog {ECO:0000313|Ensembl:ENSP00000451025};+++[H0YJT0_HUMAN|Unreviewed]SubName: Full=Protein NRDE2 homolog {ECO:0000313|Ensembl:ENSP00000452071}; Flags: Fragment;+++[H0YJT6_HUMAN|Unreviewed]SubName: Full=Protein NRDE2 homolog {ECO:0000313|Ensembl:ENSP00000452107}; Flags: Fragment;+++[Q0VFW7_HUMAN|Unreviewed]SubName: Full=C14orf102 protein {ECO:0000313|EMBL:AAI18674.1}; SubName: Full=Chromosome 14 open reading frame 102, isoform CRA_b {ECO:0000313|EMBL:EAW81423.1};"]
[5507,"'PPP1R3C'",1467,1844,1655.5,"04931///Insulin resistance+++04910///Insulin signaling pathway",{"$nulls":3},"GO:0005829///cytosol","GO:0004722///protein serine/threonine phosphatase activity+++GO:0019888///protein phosphatase regulator activity+++GO:0019903///protein phosphatase binding+++GO:0005515///protein binding","GO:0005978///glycogen biosynthetic process+++GO:0006470///protein dephosphorylation+++GO:0005977///glycogen metabolic process+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0005975///carbohydrate metabolic process","IPR030683///Protein phosphatase 1 regulatory subunit 3C+++IPR005036///CBM21 (carbohydrate binding type-21) domain+++IPR038175///CBM21 domain superfamily+++IPR017434///Protein phosphatase 1 regulatory subunit 3B/C/D, metazoa","[PPR3C_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1 regulatory subunit 3C; AltName: Full=Protein phosphatase 1 regulatory subunit 5; Short=PP1 subunit R5; AltName: Full=Protein targeting to glycogen; Short=PTG;"]
[55090,"'MED9'",111,129,120,"04934///Cushing's syndrome+++04713///Circadian entrainment","H01431///Cushing's syndrome+++H01102///Pituitary adenomas",null,null,"GO:0005654///nucleoplasm+++GO:0044798///nuclear transcription factor complex+++GO:0005634///nucleus+++GO:0016592///mediator complex","GO:0046965///retinoid X receptor binding+++GO:0005515///protein binding+++GO:0042974///retinoic acid receptor binding+++GO:0008134///transcription factor binding+++GO:0003712///transcription coregulator activity","GO:2001178///positive regulation of mediator complex assembly+++GO:0035563///positive regulation of chromatin binding+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071158///positive regulation of cell cycle arrest+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR039242///Mediator of RNA polymerase II transcription subunit 9, metazoan+++IPR011425///Mediator of RNA polymerase II transcription subunit 9+++IPR037212///Mediator complex, subunit Med7/Med21-like","[MED9_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 9; AltName: Full=Mediator complex subunit 9;+++[J3KTK5_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit 9 {ECO:0000313|EMBL:CDI06891.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 9 {ECO:0000313|Ensembl:ENSP00000463031};"]
[55109,"'AGGF1'",402,413,407.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0003676///nucleic acid binding","GO:0030154///cell differentiation+++GO:0001525///angiogenesis+++GO:0001570///vasculogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0007155///cell adhesion+++GO:0007275///multicellular organism development+++GO:0001938///positive regulation of endothelial cell proliferation","IPR035624///AGGF1, OCRE domain+++IPR000467///G-patch domain+++IPR008984///SMAD/FHA domain superfamily+++IPR000253///Forkhead-associated (FHA) domain","[AGGF1_HUMAN|Reviewed]RecName: Full=Angiogenic factor with G patch and FHA domains 1; AltName: Full=Angiogenic factor VG5Q; Short=hVG5Q; AltName: Full=G patch domain-containing protein 7; AltName: Full=Vasculogenesis gene on 5q protein;+++[A0JLT8_HUMAN|Unreviewed]SubName: Full=AGGF1 protein {ECO:0000313|EMBL:AAH15478.1}; Flags: Fragment;+++[A8K029_HUMAN|Unreviewed]SubName: Full=Angiogenic factor with G patch and FHA domains 1, isoform CRA_a {ECO:0000313|EMBL:EAW95787.1}; SubName: Full=cDNA FLJ75192 {ECO:0000313|EMBL:BAF82083.1};+++[H0Y8F8_HUMAN|Unreviewed]SubName: Full=Angiogenic factor with G patch and FHA domains 1 {ECO:0000313|Ensembl:ENSP00000420874}; Flags: Fragment;+++[Q6PIK7_HUMAN|Unreviewed]SubName: Full=Angiogenic factor with G patch and FHA domains 1 {ECO:0000313|EMBL:AAH32844.1};"]
[55127,"'HEATR1'",551,653,602,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0034455///t-UTP complex+++GO:0030686///90S preribosome+++GO:0005739///mitochondrion+++GO:0005730///nucleolus+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0032040///small-subunit processome+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0030515///snoRNA binding+++GO:0003723///RNA binding","GO:2000234///positive regulation of rRNA processing+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0042254///ribosome biogenesis+++GO:0045943///positive regulation of transcription by RNA polymerase I+++GO:0006364///rRNA processing","IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical+++IPR022125///U3 small nucleolar RNA-associated protein 10, N-terminal+++IPR012954///BP28, C-terminal domain","[HEAT1_HUMAN|Reviewed]RecName: Full=HEAT repeat-containing protein 1; AltName: Full=Protein BAP28; AltName: Full=U3 small nucleolar RNA-associated protein 10 homolog; Contains: RecName: Full=HEAT repeat-containing protein 1, N-terminally processed;+++[A0A024R3R7_HUMAN|Unreviewed]SubName: Full=HEAT repeat containing 1, isoform CRA_b {ECO:0000313|EMBL:EAW70062.1};+++[A2VDI1_HUMAN|Unreviewed]SubName: Full=HEATR1 protein {ECO:0000313|EMBL:AAI30001.1}; Flags: Fragment;+++[B2RWN5_HUMAN|Unreviewed]SubName: Full=HEAT repeat containing 1 {ECO:0000313|EMBL:AAI50615.1};+++[Q5T3Q7_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000355540};+++[Q6P664_HUMAN|Unreviewed]SubName: Full=HEAT repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000355538}; SubName: Full=HEATR1 protein {ECO:0000313|EMBL:AAH62442.1};+++[Q96ES5_HUMAN|Unreviewed]SubName: Full=HEATR1 protein {ECO:0000313|EMBL:AAH11983.1};"]
[55145,"'THAP1'",81,106,93.5,{"$nulls":4},"GO:0001650///fibrillar center+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0016605///PML body+++GO:0005654///nucleoplasm","GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0008270///zinc ion binding+++GO:0043565///sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006351///transcription, DNA-templated+++GO:0007049///cell cycle+++GO:0001935///endothelial cell proliferation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0007346///regulation of mitotic cell cycle+++GO:0006355///regulation of transcription, DNA-templated","IPR006612///THAP-type zinc finger+++IPR038441///THAP-type zinc finger superfamily+++IPR026516///THAP domain-containing protein 1","[THAP1_HUMAN|Reviewed]RecName: Full=THAP domain-containing protein 1;+++[E9PIS9_HUMAN|Unreviewed]SubName: Full=THAP domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000433912}; Flags: Fragment;"]
[55160,"'ARHGEF10L'",463,452,457.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005096///GTPase activator activity","GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0032933///SREBP signaling pathway+++GO:0051496///positive regulation of stress fiber assembly","IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR000219///Dbl homology (DH) domain+++IPR036322///WD40-repeat-containing domain superfamily+++IPR011993///PH-like domain superfamily+++IPR035899///Dbl homology (DH) domain superfamily+++IPR039919///Rho guanine nucleotide exchange factor 10/17","[ARGAL_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 10-like protein; AltName: Full=GrinchGEF;+++[A0A2X0U2F8_HUMAN|Unreviewed]SubName: Full=ARHGEF10L {ECO:0000313|EMBL:SPT35721.1}; Flags: Fragment;+++[B4DTL3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53192, highly similar to Homo sapiens Rho guanine nucleotide exchange factor (GEF) 10-like, transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62025.1};+++[Q5VXI4_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 10-like protein {ECO:0000313|Ensembl:ENSP00000364557};"]
[55178,"'MRM3'",112,102,107,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008173///RNA methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0070039///rRNA (guanosine-2'-O-)-methyltransferase activity+++GO:0003723///RNA binding","GO:0006364///rRNA processing+++GO:0006396///RNA processing+++GO:0000451///rRNA 2'-O-methylation+++GO:0032259///methylation","IPR001537///tRNA/rRNA methyltransferase, SpoU type+++IPR013123///RNA 2-O ribose methyltransferase, substrate binding+++IPR029064///50S ribosomal protein L30e-like+++IPR029028///Alpha/beta knot methyltransferases","[MRM3_HUMAN|Reviewed]RecName: Full=rRNA methyltransferase 3, mitochondrial {ECO:0000303|PubMed:25009282}; EC=2.1.1.- {ECO:0000305|PubMed:24036117, ECO:0000305|PubMed:25074936}; AltName: Full=16S rRNA (guanosine(1370)-2'-O)-methyltransferase {ECO:0000303|PubMed:25074936}; AltName: Full=16S rRNA [Gm1370] 2'-O-methyltransferase {ECO:0000303|PubMed:25074936}; AltName: Full=RNA methyltransferase-like protein 1 {ECO:0000303|PubMed:12296377}; Flags: Precursor;+++[I3L0T6_HUMAN|Unreviewed]SubName: Full=rRNA methyltransferase 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000458328};+++[I3L443_HUMAN|Unreviewed]SubName: Full=rRNA methyltransferase 3, mitochondrial {ECO:0000313|Ensembl:ENSP00000460957}; Flags: Fragment;"]
[55193,"'PBRM1'",467,664,565.5,"05225///Hepatocellular carcinoma",{"$nulls":3},"GO:0000228///nuclear chromosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016586///RSC-type complex","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0003682///chromatin binding+++GO:0015616///DNA translocase activity","GO:0006338///chromatin remodeling+++GO:0006337///nucleosome disassembly+++GO:0008285///negative regulation of cell proliferation+++GO:0000278///mitotic cell cycle+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006325///chromatin organization+++GO:0043044///ATP-dependent chromatin remodeling","IPR037382///Remodelling complex subunit Rsc/polybromo+++IPR009071///High mobility group box domain+++IPR036427///Bromodomain-like superfamily+++IPR018359///Bromodomain, conserved site+++IPR001025///Bromo adjacent homology (BAH) domain+++IPR001487///Bromodomain+++IPR036910///High mobility group box domain superfamily+++IPR037968///Protein polybromo-1, Bromodomain 5","[PB1_HUMAN|Reviewed]RecName: Full=Protein polybromo-1; Short=hPB1; AltName: Full=BRG1-associated factor 180; Short=BAF180; AltName: Full=Polybromo-1D;+++[C9J053_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000412401}; Flags: Fragment;+++[C9J409_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000411895}; Flags: Fragment;+++[C9J9L6_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000397399}; Flags: Fragment;+++[C9JCJ2_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000416851}; Flags: Fragment;+++[C9JPI5_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000409939}; Flags: Fragment;+++[C9JQF1_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000389390}; Flags: Fragment;+++[E7EVG2_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000387775}; Flags: Fragment;+++[H0Y5B5_HUMAN|Unreviewed]SubName: Full=Protein polybromo-1 {ECO:0000313|Ensembl:ENSP00000397662}; Flags: Fragment;+++[Q5EBM5_HUMAN|Unreviewed]SubName: Full=PB1 protein {ECO:0000313|EMBL:AAH89409.1}; Flags: Fragment;"]
[55208,"'DCUN1D2'",120.68,110.13,115.405,{"$nulls":4},"GO:0000151///ubiquitin ligase complex","GO:0031624///ubiquitin conjugating enzyme binding+++GO:0097602///cullin family protein binding+++GO:0032182///ubiquitin-like protein binding","GO:0051443///positive regulation of ubiquitin-protein transferase activity+++GO:0045116///protein neddylation","IPR009060///UBA-like superfamily+++IPR005176///Potentiating neddylation domain+++IPR014764///Defective-in-cullin neddylation protein","[DCNL2_HUMAN|Reviewed]RecName: Full=DCN1-like protein 2; AltName: Full=DCUN1 domain-containing protein 2; AltName: Full=Defective in cullin neddylation protein 1-like protein 2;+++[A0A0C4DFQ9_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131};+++[C9J2J1_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[C9J2J3_HUMAN|Unreviewed]SubName: Full=DCN1-like protein 2 {ECO:0000313|Ensembl:ENSP00000417394}; Flags: Fragment;+++[C9JAV2_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[C9JRE2_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[H7C216_HUMAN|Unreviewed]RecName: Full=DCN1-like protein {ECO:0000256|RuleBase:RU363131}; AltName: Full=Defective in cullin neddylation protein 1-like protein {ECO:0000256|RuleBase:RU363131}; Flags: Fragment;+++[L8E9L0_HUMAN|Unreviewed]SubName: Full=Alternative protein DCUN1D2 {ECO:0000313|EMBL:CCQ43038.1};"]
[55224,"'ETNK2'",276,209,242.5,"01100///Metabolic pathways+++00564///Glycerophospholipid metabolism",null,"M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE","R01468///ATP:ethanolamine O-phosphotransferase   ATP + Ethanolamine <=> ADP + Ethanolamine phosphate","GO:0005575///cellular_component+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004305///ethanolamine kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding","GO:0001701///in utero embryonic development+++GO:0016310///phosphorylation+++GO:0009791///post-embryonic development+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008150///biological_process+++GO:0006629///lipid metabolic process+++GO:0035264///multicellular organism growth+++GO:0001890///placenta development+++GO:0008654///phospholipid biosynthetic process","IPR011009///Protein kinase-like domain superfamily","[EKI2_HUMAN|Reviewed]RecName: Full=Ethanolamine kinase 2; Short=EKI 2; EC=2.7.1.82; AltName: Full=Ethanolamine kinase-like protein;+++[A0A024R976_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2, isoform CRA_a {ECO:0000313|EMBL:EAW91503.1};+++[A0A024R9A8_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2, isoform CRA_b {ECO:0000313|EMBL:EAW91504.1};+++[B7Z1G7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52473, highly similar to Ethanolamine kinase 2 {ECO:0000313|EMBL:BAH11503.1}; SubName: Full=cDNA, FLJ79392, highly similar to Ethanolamine kinase 2 {ECO:0000313|EMBL:BAH14864.1};+++[B7ZC34_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2 {ECO:0000313|Ensembl:ENSP00000398091}; Flags: Fragment;+++[B7ZC35_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2 {ECO:0000313|Ensembl:ENSP00000394618}; Flags: Fragment;+++[H0Y771_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2 {ECO:0000313|Ensembl:ENSP00000410580}; Flags: Fragment;+++[L8ECH7_HUMAN|Unreviewed]SubName: Full=Alternative protein ETNK2 {ECO:0000313|EMBL:CCQ43587.1};+++[Q5SXX4_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2 {ECO:0000313|Ensembl:ENSP00000356165};+++[Q5SXX7_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2 {ECO:0000313|Ensembl:ENSP00000406241}; Flags: Fragment;+++[Q5SXX8_HUMAN|Unreviewed]SubName: Full=Ethanolamine kinase 2 {ECO:0000313|Ensembl:ENSP00000405497}; Flags: Fragment;"]
[55240,"'STEAP3'",571,467,519,"04115///p53 signaling pathway+++04216///Ferroptosis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005768///endosome+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005771///multivesicular body","GO:0005515///protein binding+++GO:0008823///cupric reductase activity+++GO:0016723///oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor+++GO:0016491///oxidoreductase activity+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0052851///ferric-chelate reductase (NADPH) activity","GO:0042981///regulation of apoptotic process+++GO:0006811///ion transport+++GO:0033572///transferrin transport+++GO:0006915///apoptotic process+++GO:0015677///copper ion import+++GO:0009306///protein secretion+++GO:0098706///ferric iron import across cell outer membrane+++GO:0007049///cell cycle+++GO:0055072///iron ion homeostasis+++GO:0055114///oxidation-reduction process","IPR028939///Pyrroline-5-carboxylate reductase, catalytic, N-terminal+++IPR013130///Ferric reductase transmembrane component-like domain+++IPR036291///NAD(P)-binding domain superfamily","[STEA3_HUMAN|Reviewed]RecName: Full=Metalloreductase STEAP3; EC=1.16.1.-; AltName: Full=Dudulin-2; AltName: Full=Six-transmembrane epithelial antigen of prostate 3; AltName: Full=Tumor suppressor-activated pathway protein 6; Short=hTSAP6; AltName: Full=pHyde; Short=hpHyde;+++[A0A024RAD7_HUMAN|Unreviewed]SubName: Full=STEAP family member 3, isoform CRA_b {ECO:0000313|EMBL:EAW95212.1};+++[B8ZZX6_HUMAN|Unreviewed]SubName: Full=Metalloreductase STEAP3 {ECO:0000313|Ensembl:ENSP00000386510}; SubName: Full=STEAP family member 3, isoform CRA_c {ECO:0000313|EMBL:EAW95211.1};"]
[55257,"'MRGBP'",230,188,209,{"$nulls":4},"GO:0035267///NuA4 histone acetyltransferase complex+++GO:0043189///H4/H2A histone acetyltransferase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0016573///histone acetylation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006325///chromatin organization+++GO:0040008///regulation of growth","IPR012423///Chromatin modification-related protein Eaf7/MRGBP","[MRGBP_HUMAN|Reviewed]RecName: Full=MRG/MORF4L-binding protein; AltName: Full=MRG-binding protein; AltName: Full=Up-regulated in colon cancer 4; Short=Urcc4;"]
[55276,"'PGM2'",157,139,148,"01130///Biosynthesis of antibiotics+++00052///Galactose metabolism+++00030///Pentose phosphate pathway+++00500///Starch and sucrose metabolism+++00010///Glycolysis / Gluconeogenesis+++00230///Purine metabolism+++01100///Metabolic pathways+++00520///Amino sugar and nucleotide sugar metabolism+++01120///Microbial metabolism in diverse environments+++01110///Biosynthesis of secondary metabolites",null,null,"R02749///2-deoxy-D-ribose 1-phosphate 1,5-phosphomutase   2-Deoxy-D-ribose 1-phosphate <=> 2-Deoxy-D-ribose 5-phosphate+++R00959///alpha-D-Glucose 1-phosphate 1,6-phosphomutase   D-Glucose 1-phosphate <=> alpha-D-Glucose 6-phosphate+++R01057///D-Ribose 1,5-phosphomutase   alpha-D-Ribose 1-phosphate <=> D-Ribose 5-phosphate","GO:0034774///secretory granule lumen+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005576///extracellular region+++GO:1904813///ficolin-1-rich granule lumen","GO:0004614///phosphoglucomutase activity+++GO:0008973///phosphopentomutase activity+++GO:0016853///isomerase activity+++GO:0046872///metal ion binding+++GO:0016868///intramolecular transferase activity, phosphotransferases+++GO:0005515///protein binding+++GO:0000287///magnesium ion binding","GO:0043312///neutrophil degranulation+++GO:0006098///pentose-phosphate shunt+++GO:0071704///organic substance metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0005980///glycogen catabolic process+++GO:0005978///glycogen biosynthetic process+++GO:0006006///glucose metabolic process+++GO:0046386///deoxyribose phosphate catabolic process+++GO:0019388///galactose catabolic process","IPR016066///Alpha-D-phosphohexomutase, conserved site+++IPR036900///Alpha-D-phosphohexomutase, C-terminal domain superfamily+++IPR005841///Alpha-D-phosphohexomutase superfamily+++IPR005844///Alpha-D-phosphohexomutase, alpha/beta/alpha domain I+++IPR005846///Alpha-D-phosphohexomutase, alpha/beta/alpha domain III+++IPR016055///Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III+++IPR005845///Alpha-D-phosphohexomutase, alpha/beta/alpha domain II+++IPR005843///Alpha-D-phosphohexomutase, C-terminal","[PGM2_HUMAN|Reviewed]RecName: Full=Phosphoglucomutase-2; Short=PGM 2; EC=5.4.2.2; AltName: Full=Glucose phosphomutase 2; AltName: Full=Phosphodeoxyribomutase; AltName: Full=Phosphopentomutase; EC=5.4.2.7;+++[E7ENQ8_HUMAN|Unreviewed]SubName: Full=Phosphoglucomutase-2 {ECO:0000313|Ensembl:ENSP00000423269};+++[E9PD70_HUMAN|Unreviewed]SubName: Full=Phosphoglucomutase-2 {ECO:0000313|Ensembl:ENSP00000425733};+++[H0Y921_HUMAN|Unreviewed]SubName: Full=Phosphoglucomutase-2 {ECO:0000313|Ensembl:ENSP00000422785}; Flags: Fragment;"]
[5529,"'PPP2R5E'",565,730,647.5,"04152///AMPK signaling pathway+++04151///PI3K-Akt signaling pathway+++04728///Dopaminergic synapse+++04114///Oocyte meiosis+++05165///Human papillomavirus infection+++04071///Sphingolipid signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04113///Meiosis - yeast+++03015///mRNA surveillance pathway","H00773///Autosomal dominant mental retardation",null,null,"GO:0000159///protein phosphatase type 2A complex+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0019888///protein phosphatase regulator activity+++GO:0005515///protein binding+++GO:0072542///protein phosphatase activator activity","GO:0031952///regulation of protein autophosphorylation+++GO:0007165///signal transduction+++GO:0043666///regulation of phosphoprotein phosphatase activity","IPR011989///Armadillo-like helical+++IPR002554///Protein phosphatase 2A, regulatory B subunit, B56+++IPR016024///Armadillo-type fold","[2A5E_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; AltName: Full=PP2A B subunit isoform B'-epsilon; AltName: Full=PP2A B subunit isoform B56-epsilon; AltName: Full=PP2A B subunit isoform PR61-epsilon; AltName: Full=PP2A B subunit isoform R5-epsilon;+++[B5BTZ7_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit {ECO:0000256|PIRNR:PIRNR028043};+++[Q562F2_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit {ECO:0000256|PIRNR:PIRNR028043};+++[Q58EX4_HUMAN|Unreviewed]SubName: Full=PPP2R5E protein {ECO:0000313|EMBL:AAH64358.1}; Flags: Fragment;+++[Q86XZ2_HUMAN|Unreviewed]SubName: Full=PPP2R5E protein {ECO:0000313|EMBL:AAH48305.1}; Flags: Fragment;"]
[5531,"'PPP4C'",2488,1809,2148.5,"04922///Glucagon signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030289///protein phosphatase 4 complex+++GO:0005815///microtubule organizing center+++GO:0005886///plasma membrane","GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity+++GO:0004704///NF-kappaB-inducing kinase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004722///protein serine/threonine phosphatase activity","GO:0038061///NIK/NF-kappaB signaling+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006470///protein dephosphorylation","IPR004843///Calcineurin-like phosphoesterase domain, ApaH type+++IPR006186///Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase+++IPR029052///Metallo-dependent phosphatase-like","[PP4C_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 4 catalytic subunit; Short=PP4C; Short=Pp4; EC=3.1.3.16 {ECO:0000269|PubMed:18347064, ECO:0000269|PubMed:18614045, ECO:0000269|PubMed:18758438, ECO:0000269|PubMed:20154705}; AltName: Full=Protein phosphatase X; Short=PP-X;+++[A0A024R625_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};+++[H3BPN5_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 catalytic subunit {ECO:0000313|Ensembl:ENSP00000455394};+++[H3BTA2_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[H3BV22_HUMAN|Unreviewed]RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273}; EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273}; Flags: Fragment;+++[H3BVE3_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 catalytic subunit {ECO:0000313|Ensembl:ENSP00000458079};+++[I3L4X0_HUMAN|Unreviewed]SubName: Full=Protein phosphatase 4 (Formerly X), catalytic subunit, isoform CRA_b {ECO:0000313|EMBL:EAW79930.1}; SubName: Full=Serine/threonine-protein phosphatase 4 catalytic subunit {ECO:0000313|Ensembl:ENSP00000461609};"]
[55324,"'ABCF3'",814,749,781.5,{"$nulls":4},"GO:0016020///membrane","GO:0016887///ATPase activity+++GO:0045296///cadherin binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0051607///defense response to virus","IPR032781///ABC-transporter extension domain+++IPR003593///AAA+ ATPase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR017871///ABC transporter, conserved site+++IPR003439///ABC transporter-like","[ABCF3_HUMAN|Reviewed]RecName: Full=ATP-binding cassette sub-family F member 3;+++[A0A0S2Z5L1_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 3 isoform 1 {ECO:0000313|EMBL:ALQ34152.1}; SubName: Full=ATP-binding cassette, sub-family F (GCN20), member 3, isoform CRA_a {ECO:0000313|EMBL:EAW78288.1}; Flags: Fragment;+++[A0A0S2Z645_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 3 isoform 2 {ECO:0000313|EMBL:ALQ34153.1};+++[F8WCU6_HUMAN|Unreviewed]SubName: Full=ATP-binding cassette sub-family F member 3 {ECO:0000313|Ensembl:ENSP00000415704};"]
[55339,"'WDR33'",382,386,384,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005581///collagen trimer+++GO:0001650///fibrillar center+++GO:0005847///mRNA cleavage and polyadenylation specificity factor complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0003723///RNA binding","GO:0006301///postreplication repair+++GO:0007283///spermatogenesis+++GO:0031124///mRNA 3'-end processing+++GO:0006378///mRNA polyadenylation+++GO:0006369///termination of RNA polymerase II transcription+++GO:0006406///mRNA export from nucleus+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","IPR036322///WD40-repeat-containing domain superfamily+++IPR017986///WD40-repeat-containing domain+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR001680///WD40 repeat","[WDR33_HUMAN|Reviewed]RecName: Full=pre-mRNA 3' end processing protein WDR33; AltName: Full=WD repeat-containing protein 33; AltName: Full=WD repeat-containing protein WDC146;+++[B9A053_HUMAN|Unreviewed]SubName: Full=pre-mRNA 3' end-processing protein WDR33 {ECO:0000313|Ensembl:ENSP00000386861}; Flags: Fragment;+++[C9J8B4_HUMAN|Unreviewed]SubName: Full=pre-mRNA 3' end-processing protein WDR33 {ECO:0000313|Ensembl:ENSP00000397547}; Flags: Fragment;"]
[5534,"'PPP3R1'",491,601,546,"04022///cGMP-PKG signaling pathway+++04922///Glucagon signaling pathway+++04020///Calcium signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++04662///B cell receptor signaling pathway+++04921///Oxytocin signaling pathway+++04380///Osteoclast differentiation+++04010///MAPK signaling pathway+++04659///Th17 cell differentiation+++04310///Wnt signaling pathway+++05010///Alzheimer's disease+++04370///VEGF signaling pathway+++05031///Amphetamine addiction+++05152///Tuberculosis+++05166///HTLV-I infection+++04625///C-type lectin receptor signaling pathway+++04724///Glutamatergic synapse+++04218///Cellular senescence+++04720///Long-term potentiation+++04114///Oocyte meiosis+++04658///Th1 and Th2 cell differentiation+++05163///Human cytomegalovirus infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04924///Renin secretion+++04660///T cell receptor signaling pathway+++05014///Amyotrophic lateral sclerosis (ALS)+++04360///Axon guidance",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0042383///sarcolemma+++GO:0005886///plasma membrane+++GO:0005955///calcineurin complex+++GO:0005654///nucleoplasm","GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0004723///calcium-dependent protein serine/threonine phosphatase activity+++GO:0016018///cyclosporin A binding+++GO:0019902///phosphatase binding+++GO:0005516///calmodulin binding","GO:0006470///protein dephosphorylation+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:0033173///calcineurin-NFAT signaling cascade","IPR002048///EF-hand domain+++IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair","[CANB1_HUMAN|Reviewed]RecName: Full=Calcineurin subunit B type 1; AltName: Full=Protein phosphatase 2B regulatory subunit 1; AltName: Full=Protein phosphatase 3 regulatory subunit B alpha isoform 1;+++[D3YTA9_HUMAN|Unreviewed]SubName: Full=Calcineurin subunit B type 1 {ECO:0000313|Ensembl:ENSP00000387216};+++[F6U1T9_HUMAN|Unreviewed]SubName: Full=Calcineurin subunit B type 1 {ECO:0000313|Ensembl:ENSP00000387148};"]
[55357,"'TBC1D2'",5470,4617,5043.5,{"$nulls":4},"GO:0031410///cytoplasmic vesicle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030054///cell junction","GO:0045296///cadherin binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport+++GO:0043547///positive regulation of GTPase activity+++GO:1902017///regulation of cilium assembly","IPR000195///Rab-GTPase-TBC domain+++IPR001849///Pleckstrin homology domain+++IPR011993///PH-like domain superfamily+++IPR035969///Rab-GTPase-TBC domain superfamily","[TBD2A_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 2A; AltName: Full=Armus; AltName: Full=Prostate antigen recognized and identified by SEREX 1; Short=PARIS-1;+++[A0A024R166_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 2, isoform CRA_f {ECO:0000313|EMBL:EAW58888.1};"]
[55421,"'NCBP3'",435,512,473.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0034518///RNA cap binding complex","GO:0003723///RNA binding+++GO:0000340///RNA 7-methylguanosine cap binding+++GO:0003729///mRNA binding+++GO:0005515///protein binding+++GO:0000339///RNA cap binding","GO:0051607///defense response to virus+++GO:0006370///7-methylguanosine mRNA capping+++GO:0051028///mRNA transport+++GO:0006397///mRNA processing","IPR019416///Nuclear cap-binding protein subunit 3+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[NCBP3_HUMAN|Reviewed]RecName: Full=Nuclear cap-binding protein subunit 3 {ECO:0000312|HGNC:HGNC:24612}; AltName: Full=Protein ELG;+++[K7ELP6_HUMAN|Unreviewed]SubName: Full=Nuclear cap-binding protein subunit 3 {ECO:0000313|Ensembl:ENSP00000466165}; Flags: Fragment;+++[K7EQA5_HUMAN|Unreviewed]SubName: Full=Nuclear cap-binding protein subunit 3 {ECO:0000313|Ensembl:ENSP00000467742}; Flags: Fragment;+++[L0R6D6_HUMAN|Unreviewed]SubName: Full=Alternative protein C17orf85 {ECO:0000313|EMBL:CCO13690.1};"]
[55486,"'PARL'",225,191,208,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane","GO:0004252///serine-type endopeptidase activity+++GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0004175///endopeptidase activity+++GO:0008236///serine-type peptidase activity","GO:0030162///regulation of proteolysis+++GO:2000377///regulation of reactive oxygen species metabolic process+++GO:1903214///regulation of protein targeting to mitochondrion+++GO:0033619///membrane protein proteolysis+++GO:0006508///proteolysis+++GO:0010821///regulation of mitochondrion organization","IPR022764///Peptidase S54, rhomboid domain+++IPR035952///Rhomboid-like superfamily","[PARL_HUMAN|Reviewed]RecName: Full=Presenilins-associated rhomboid-like protein, mitochondrial; EC=3.4.21.105; AltName: Full=Mitochondrial intramembrane cleaving protease PARL; Contains: RecName: Full=P-beta; Short=Pbeta; Flags: Precursor;+++[A0A1W2PP66_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000491186};+++[A0A1W2PS40_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000492596};+++[C9JNP8_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000402137};+++[F8WCQ4_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000404421};+++[H7C045_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000392926}; Flags: Fragment;+++[H7C0U0_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000396691}; Flags: Fragment;+++[H7C122_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000398043}; Flags: Fragment;+++[H7C1V6_HUMAN|Unreviewed]SubName: Full=Presenilins-associated rhomboid-like protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000402689}; Flags: Fragment;"]
[5552,"'SRGN'",2,0,1,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0042629///mast cell granule+++GO:0031093///platelet alpha granule lumen","GO:0005515///protein binding","GO:0008626///granzyme-mediated apoptotic signaling pathway+++GO:0050710///negative regulation of cytokine secretion+++GO:0033382///maintenance of granzyme B location in T cell secretory granule+++GO:0006915///apoptotic process+++GO:0033371///T cell secretory granule organization+++GO:0033373///maintenance of protease location in mast cell secretory granule+++GO:0016485///protein processing+++GO:0002576///platelet degranulation+++GO:0031214///biomineral tissue development+++GO:0030502///negative regulation of bone mineralization+++GO:0033364///mast cell secretory granule organization","IPR007455///Serglycin","[SRGN_HUMAN|Reviewed]RecName: Full=Serglycin; AltName: Full=Hematopoietic proteoglycan core protein; AltName: Full=Platelet proteoglycan core protein; Short=P.PG; AltName: Full=Secretory granule proteoglycan core protein; Flags: Precursor;"]
[55552,"'ZNF823'",21,24,22.5,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN823_HUMAN|Reviewed]RecName: Full=Zinc finger protein 823; AltName: Full=Zinc finger protein ZFP-36;+++[C9J2N8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 823 {ECO:0000313|Ensembl:ENSP00000410654}; Flags: Fragment;+++[C9JU45_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 823 {ECO:0000313|Ensembl:ENSP00000387514};+++[K7EN93_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 823 {ECO:0000313|Ensembl:ENSP00000466840}; Flags: Fragment;"]
[5558,"'PRIM2'",97,80,88.5,"01100///Metabolic pathways+++00240///Pyrimidine metabolism+++00230///Purine metabolism+++03030///DNA replication",null,"M00261///DNA polymerase alpha / primase complex","R00378///deoxythymidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dTTP + DNA <=> Diphosphate + DNA+++R00376///Deoxyguanosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dGTP + DNA <=> Diphosphate + DNA+++R00375///Deoxyadenosine 5'-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dATP + DNA <=> Diphosphate + DNA+++R00377///Deoxycytidine triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)   dCTP + DNA <=> Diphosphate + DNA","GO:0005654///nucleoplasm+++GO:0005658///alpha DNA polymerase:primase complex","GO:0003896///DNA primase activity+++GO:0016740///transferase activity+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0003677///DNA binding+++GO:0051536///iron-sulfur cluster binding+++GO:0005515///protein binding+++GO:0016779///nucleotidyltransferase activity+++GO:0046872///metal ion binding+++GO:0003697///single-stranded DNA binding","GO:0032201///telomere maintenance via semi-conservative replication+++GO:0006269///DNA replication, synthesis of RNA primer+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0006260///DNA replication","IPR007238///DNA primase large subunit, eukaryotic/archaeal+++IPR016558///DNA primase, large subunit, eukaryotic","[PRI2_HUMAN|Reviewed]RecName: Full=DNA primase large subunit; EC=2.7.7.-; AltName: Full=DNA primase 58 kDa subunit; Short=p58;+++[A0A024RD43_HUMAN|Unreviewed]SubName: Full=Primase, polypeptide 2A, 58kDa, isoform CRA_b {ECO:0000313|EMBL:EAX04483.1};+++[A0A024RD63_HUMAN|Unreviewed]SubName: Full=Primase, polypeptide 2A, 58kDa, isoform CRA_a {ECO:0000313|EMBL:EAX04482.1}; Flags: Fragment;+++[A0A096LP51_HUMAN|Unreviewed]SubName: Full=DNA primase large subunit {ECO:0000313|Ensembl:ENSP00000485395}; Flags: Fragment;+++[H9XFA6_HUMAN|Unreviewed]SubName: Full=Primase DNA polypeptide 2 {ECO:0000313|EMBL:AFG72972.1}; Flags: Fragment;+++[H9XFA7_HUMAN|Unreviewed]SubName: Full=Primase DNA polypeptide 2 {ECO:0000313|EMBL:AFG72973.1}; Flags: Fragment;+++[I0CMJ8_HUMAN|Unreviewed]SubName: Full=DNA primase large subunit {ECO:0000313|EMBL:AFH78579.1}; Flags: Fragment;+++[I0CMK6_HUMAN|Unreviewed]SubName: Full=DNA primase large subunit {ECO:0000313|EMBL:AFH78587.1}; Flags: Fragment;+++[I0EZ64_HUMAN|Unreviewed]SubName: Full=DNA primase large subunit {ECO:0000313|EMBL:AFI24900.1}; Flags: Fragment;+++[O43807_HUMAN|Unreviewed]SubName: Full=NK receptor {ECO:0000313|EMBL:CAA04446.1}; Flags: Fragment;+++[O75755_HUMAN|Unreviewed]SubName: Full=NK receptor {ECO:0000313|EMBL:CAA04175.2}; Flags: Fragment;"]
[55605,"'KIF21A'",359,350,354.5,null,"H00658///Syndromic X-linked mental retardation+++H00838///Congenital fibrosis of the extraocular muscles (CFEOM)",null,null,"GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0003777///microtubule motor activity+++GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0005515///protein binding+++GO:0003774///motor activity","GO:0007018///microtubule-based movement","IPR001752///Kinesin motor domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR036322///WD40-repeat-containing domain superfamily+++IPR017986///WD40-repeat-containing domain+++IPR027640///Kinesin-like protein+++IPR001680///WD40 repeat+++IPR019821///Kinesin motor domain, conserved site+++IPR036961///Kinesin motor domain superfamily+++IPR019775///WD40 repeat, conserved site+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[KI21A_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF21A; AltName: Full=Kinesin-like protein KIF2; AltName: Full=Renal carcinoma antigen NY-REN-62;+++[A0A024R0V9_HUMAN|Unreviewed]SubName: Full=Kinesin family member 21A, isoform CRA_c {ECO:0000313|EMBL:EAW57805.1};+++[A0A1B0GV47_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF21A {ECO:0000313|Ensembl:ENSP00000490369}; Flags: Fragment;+++[H0YHG9_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF21A {ECO:0000313|Ensembl:ENSP00000447070}; Flags: Fragment;+++[H0YHT2_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF21A {ECO:0000313|Ensembl:ENSP00000447765}; Flags: Fragment;+++[H0YI78_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF21A {ECO:0000313|Ensembl:ENSP00000448792}; Flags: Fragment;+++[H0YIM6_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF21A {ECO:0000313|Ensembl:ENSP00000449698}; Flags: Fragment;+++[H0YIM7_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394}; Flags: Fragment;"]
[55622,"'TTC27'",132,150,141,{"$nulls":4},"GO:0005575///cellular_component","GO:0003674///molecular_function","GO:0008150///biological_process","IPR019734///Tetratricopeptide repeat+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR013105///Tetratricopeptide repeat 2","[TTC27_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 27; Short=TPR repeat protein 27;+++[B4DRC7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57829 {ECO:0000313|EMBL:BAG61239.1};+++[C9JVS4_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 27 {ECO:0000313|Ensembl:ENSP00000393327}; Flags: Fragment;+++[F8WCH1_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 27 {ECO:0000313|Ensembl:ENSP00000392883};+++[H7C178_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 27 {ECO:0000313|Ensembl:ENSP00000398820}; Flags: Fragment;+++[H7C329_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 27 {ECO:0000313|Ensembl:ENSP00000409230}; Flags: Fragment;+++[H7C3A3_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 27 {ECO:0000313|Ensembl:ENSP00000410642}; Flags: Fragment;+++[L8EA00_HUMAN|Unreviewed]SubName: Full=Alternative protein TTC27 {ECO:0000313|EMBL:CCQ43566.1};"]
[55636,"'CHD7'",234,289,261.5,null,"H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005730///nucleolus+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0016817///hydrolase activity, acting on acid anhydrides+++GO:0003682///chromatin binding+++GO:0004386///helicase activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:1990841///promoter-specific chromatin binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding","GO:0030540///female genitalia development+++GO:0035909///aorta morphogenesis+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0060021///roof of mouth development+++GO:0060429///epithelium development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043584///nose development+++GO:0042472///inner ear morphogenesis+++GO:0042471///ear morphogenesis+++GO:0030217///T cell differentiation+++GO:0048844///artery morphogenesis+++GO:0009617///response to bacterium+++GO:0007605///sensory perception of sound+++GO:0062009///secondary palate development+++GO:0007512///adult heart development+++GO:0007417///central nervous system development+++GO:0060173///limb development+++GO:0040018///positive regulation of multicellular organism growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0021553///olfactory nerve development+++GO:0060324///face development+++GO:0060411///cardiac septum morphogenesis+++GO:0050767///regulation of neurogenesis+++GO:0035904///aorta development+++GO:0048752///semicircular canal morphogenesis+++GO:0006325///chromatin organization+++GO:0006364///rRNA processing+++GO:0007628///adult walking behavior+++GO:0060384///innervation+++GO:0060041///retina development in camera-type eye+++GO:0021545///cranial nerve development+++GO:0001501///skeletal system development+++GO:0021772///olfactory bulb development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0048806///genitalia development+++GO:0008015///blood circulation+++GO:0043010///camera-type eye development+++GO:0001701///in utero embryonic development+++GO:0048771///tissue remodeling+++GO:0003222///ventricular trabecula myocardium morphogenesis+++GO:0003226///right ventricular compact myocardium morphogenesis+++GO:0042048///olfactory behavior+++GO:0060123///regulation of growth hormone secretion+++GO:0006338///chromatin remodeling+++GO:0001974///blood vessel remodeling+++GO:0007626///locomotory behavior+++GO:0036302///atrioventricular canal development+++GO:0050890///cognition+++GO:0003007///heart morphogenesis+++GO:0001568///blood vessel development","IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR000330///SNF2-related, N-terminal domain+++IPR038718///SNF2-like, N-terminal domain superfamily+++IPR006576///BRK domain+++IPR016197///Chromo-like domain superfamily+++IPR000953///Chromo/chromo shadow domain+++IPR023780///Chromo domain+++IPR001650///Helicase, C-terminal+++IPR037259///BRK domain superfamily+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[CHD7_HUMAN|Reviewed]RecName: Full=Chromodomain-helicase-DNA-binding protein 7; Short=CHD-7; EC=3.6.4.12; AltName: Full=ATP-dependent helicase CHD7;+++[A0A024R7V7_HUMAN|Unreviewed]SubName: Full=Chromodomain helicase DNA binding protein 7, isoform CRA_a {ECO:0000313|EMBL:EAW86833.1};+++[E9PP20_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000436492}; Flags: Fragment;+++[H0YD01_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000432627}; Flags: Fragment;+++[H0YDC1_HUMAN|Unreviewed]SubName: Full=Chromodomain-helicase-DNA-binding protein 7 {ECO:0000313|Ensembl:ENSP00000433336}; Flags: Fragment;+++[L8E8D7_HUMAN|Unreviewed]SubName: Full=Alternative protein CHD7 {ECO:0000313|EMBL:CCQ43570.1};+++[Q6ZWF9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ41163 fis, clone BRACE2039734 {ECO:0000313|EMBL:BAC85544.1}; Flags: Fragment;"]
[55657,"'ZNF692'",698,675,686.5,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0000122///negative regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN692_HUMAN|Reviewed]RecName: Full=Zinc finger protein 692;+++[E7ET73_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 692 {ECO:0000313|Ensembl:ENSP00000393552};+++[E9PLQ5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 692 {ECO:0000313|Ensembl:ENSP00000431343};+++[E9PLQ7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 692 {ECO:0000313|Ensembl:ENSP00000431338};+++[E9PRH5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 692 {ECO:0000313|Ensembl:ENSP00000432300}; Flags: Fragment;+++[H0YCH4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 692 {ECO:0000313|Ensembl:ENSP00000431582}; Flags: Fragment;+++[H0YDF5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 692 {ECO:0000313|Ensembl:ENSP00000433522}; Flags: Fragment;+++[H0YEY1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 692 {ECO:0000313|Ensembl:ENSP00000436814}; Flags: Fragment;"]
[55670,"'PEX26'",497,613.01,555.005,"04146///Peroxisome","H01342///Zellweger syndrome (ZS)+++H00177///Adrenoleukodystrophy, neonatal (NALD)+++H00205///Peroxisome biogenesis disorder+++H00204///Infantile Refsum disease (IRD)",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005779///integral component of peroxisomal membrane+++GO:0005777///peroxisome+++GO:0005778///peroxisomal membrane","GO:0005515///protein binding+++GO:0008022///protein C-terminus binding+++GO:0051117///ATPase binding+++GO:0044877///protein-containing complex binding","GO:0045046///protein import into peroxisome membrane+++GO:0016558///protein import into peroxisome matrix+++GO:0015031///protein transport+++GO:0006625///protein targeting to peroxisome","IPR010797///Peroxisome assembly protein 26","[PEX26_HUMAN|Reviewed]RecName: Full=Peroxisome assembly protein 26; AltName: Full=Peroxin-26;+++[A0A024R100_HUMAN|Unreviewed]SubName: Full=Peroxisomal biogenesis factor 26 isoform 1 {ECO:0000313|EMBL:ALQ34167.1}; SubName: Full=Peroxisome biogenesis factor 26, isoform CRA_a {ECO:0000313|EMBL:EAW57783.1};+++[A0A0S2Z5M7_HUMAN|Unreviewed]SubName: Full=Peroxisomal biogenesis factor 26 isoform 2 {ECO:0000313|EMBL:ALQ34168.1}; Flags: Fragment;+++[E9PRC5_HUMAN|Unreviewed]SubName: Full=Peroxisome assembly protein 26 {ECO:0000313|Ensembl:ENSP00000434235};+++[Q7Z2D7_HUMAN|Unreviewed]SubName: Full=Pex26pT35insC/del223-271 {ECO:0000313|EMBL:BAC78803.1};"]
[55691,"'FRMD4A'",1324,1616,1470,"04140///Autophagy - animal+++03040///Spliceosome+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005923///bicellular tight junction+++GO:0005912///adherens junction+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0030054///cell junction","GO:0030674///protein binding, bridging","GO:0090162///establishment of epithelial cell polarity","IPR035963///FERM superfamily, second domain+++IPR021774///Domain of unknown function DUF3338+++IPR019749///Band 4.1 domain+++IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR018979///FERM, N-terminal+++IPR011993///PH-like domain superfamily+++IPR019747///FERM conserved site+++IPR018980///FERM, C-terminal PH-like domain+++IPR029071///Ubiquitin-like domain superfamily+++IPR019748///FERM central domain+++IPR000299///FERM domain","[FRM4A_HUMAN|Reviewed]RecName: Full=FERM domain-containing protein 4A;+++[A0A0J9YWI3_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000487974}; Flags: Fragment;+++[A0A0J9YXB2_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000488325}; Flags: Fragment;+++[A0A0J9YYA7_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000488764}; Flags: Fragment;+++[A0A1W2PQE7_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000492091}; Flags: Fragment;+++[Q5T376_HUMAN|Unreviewed]SubName: Full=FERM domain containing 4A, isoform CRA_c {ECO:0000313|EMBL:EAW86277.1}; SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000264546}; Flags: Fragment;+++[Q9NW91_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10210 fis, clone HEMBA1006344, weakly similar to RADIXIN {ECO:0000313|EMBL:BAA91492.1};+++[S4R324_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000473870};+++[S4R3Y6_HUMAN|Unreviewed]SubName: Full=FERM domain-containing protein 4A {ECO:0000313|Ensembl:ENSP00000474863};"]
[55707,"'NECAP2'",1087,966,1026.5,null,"H00606///Early infantile epileptic encephalopathy",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0030125///clathrin vesicle coat+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0030665///clathrin-coated vesicle membrane+++GO:0005905///clathrin-coated pit+++GO:0005622///intracellular",null,"GO:0015031///protein transport+++GO:0006897///endocytosis","IPR011993///PH-like domain superfamily+++IPR012466///NECAP, PHear domain","[NECP2_HUMAN|Reviewed]RecName: Full=Adaptin ear-binding coat-associated protein 2; AltName: Full=NECAP endocytosis-associated protein 2; Short=NECAP-2;+++[A0A024QZ81_HUMAN|Unreviewed]SubName: Full=NECAP endocytosis associated 2, isoform CRA_c {ECO:0000313|EMBL:EAW51783.1};+++[B4DUR7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52763, highly similar to Adaptin ear-binding coat-associated protein 2 {ECO:0000313|EMBL:BAG62429.1};+++[D6RAN6_HUMAN|Unreviewed]SubName: Full=Adaptin ear-binding coat-associated protein 2 {ECO:0000313|Ensembl:ENSP00000421867};+++[D6RB24_HUMAN|Unreviewed]SubName: Full=Adaptin ear-binding coat-associated protein 2 {ECO:0000313|Ensembl:ENSP00000424509};+++[F6SKB8_HUMAN|Unreviewed]SubName: Full=Adaptin ear-binding coat-associated protein 2 {ECO:0000313|Ensembl:ENSP00000421335};+++[H0Y970_HUMAN|Unreviewed]SubName: Full=Adaptin ear-binding coat-associated protein 2 {ECO:0000313|Ensembl:ENSP00000423213}; Flags: Fragment;"]
[55723,"'ASF1B'",5,3,4,{"$nulls":4},"GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0000790///nuclear chromatin","GO:0042393///histone binding+++GO:0005515///protein binding","GO:0006336///DNA replication-independent nucleosome assembly+++GO:0007275///multicellular organism development+++GO:0006334///nucleosome assembly+++GO:0006335///DNA replication-dependent nucleosome assembly+++GO:0006333///chromatin assembly or disassembly+++GO:0007283///spermatogenesis+++GO:0001835///blastocyst hatching+++GO:0030154///cell differentiation+++GO:0006325///chromatin organization","IPR006818///Histone chaperone ASF1-like+++IPR036747///Histone chaperone ASF1-like superfamily","[ASF1B_HUMAN|Reviewed]RecName: Full=Histone chaperone ASF1B; AltName: Full=Anti-silencing function protein 1 homolog B; Short=hAsf1; Short=hAsf1b; AltName: Full=CCG1-interacting factor A-II; Short=CIA-II; Short=hCIA-II;+++[A0A024R7G4_HUMAN|Unreviewed]SubName: Full=ASF1 anti-silencing function 1 homolog B (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW84402.1};+++[K7EIL9_HUMAN|Unreviewed]SubName: Full=Histone chaperone ASF1B {ECO:0000313|Ensembl:ENSP00000464802};+++[K7ELW9_HUMAN|Unreviewed]SubName: Full=Histone chaperone ASF1B {ECO:0000313|Ensembl:ENSP00000466257};+++[K7EM93_HUMAN|Unreviewed]SubName: Full=Histone chaperone ASF1B {ECO:0000313|Ensembl:ENSP00000466409};+++[K7ES22_HUMAN|Unreviewed]SubName: Full=Histone chaperone ASF1B {ECO:0000313|Ensembl:ENSP00000468513};"]
[55741,"'EDEM2'",2396.76,1585.79,1991.275,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane+++GO:0044322///endoplasmic reticulum quality control compartment","GO:0005509///calcium ion binding+++GO:0003824///catalytic activity+++GO:0004571///mannosyl-oligosaccharide 1,2-alpha-mannosidase activity","GO:0036511///trimming of first mannose on A branch+++GO:1904154///positive regulation of retrograde protein transport, ER to cytosol+++GO:0036510///trimming of terminal mannose on C branch+++GO:0097466///ubiquitin-dependent glycoprotein ERAD pathway+++GO:0036509///trimming of terminal mannose on B branch+++GO:1904382///mannose trimming involved in glycoprotein ERAD pathway+++GO:0036512///trimming of second mannose on A branch+++GO:0006986///response to unfolded protein","IPR001382///Glycoside hydrolase family 47+++IPR036026///Seven-hairpin glycosidases+++IPR012341///Six-hairpin glycosidase-like superfamily","[EDEM2_HUMAN|Reviewed]RecName: Full=ER degradation-enhancing alpha-mannosidase-like protein 2; Flags: Precursor;"]
[55757,"'UGGT2'",339,418,378.5,"04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005783///endoplasmic reticulum+++GO:0005788///endoplasmic reticulum lumen+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0044322///endoplasmic reticulum quality control compartment","GO:0016740///transferase activity+++GO:0051082///unfolded protein binding+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0005515///protein binding+++GO:0003980///UDP-glucose:glycoprotein glucosyltransferase activity","GO:1904380///endoplasmic reticulum mannose trimming+++GO:0018279///protein N-linked glycosylation via asparagine+++GO:0006486///protein glycosylation+++GO:0071712///ER-associated misfolded protein catabolic process+++GO:0097359///UDP-glucosylation","IPR009448///UDP-glucose:Glycoprotein Glucosyltransferase+++IPR029044///Nucleotide-diphospho-sugar transferases+++IPR002495///Glycosyl transferase, family 8","[UGGG2_HUMAN|Reviewed]RecName: Full=UDP-glucose:glycoprotein glucosyltransferase 2; Short=UGT2; Short=hUGT2; EC=2.4.1.-; AltName: Full=UDP--Glc:glycoprotein glucosyltransferase 2; AltName: Full=UDP-glucose ceramide glucosyltransferase-like 1; Flags: Precursor;+++[A0A087WYR2_HUMAN|Unreviewed]SubName: Full=UDP-glucose:glycoprotein glucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000482021};+++[A0A1W2PQ18_HUMAN|Unreviewed]SubName: Full=UDP-glucose:glycoprotein glucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000491729};+++[A6NP03_HUMAN|Unreviewed]SubName: Full=UDP-glucose:glycoprotein glucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000365902};+++[E7EMU6_HUMAN|Unreviewed]SubName: Full=UDP-glucose:glycoprotein glucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000380743};+++[Q05D90_HUMAN|Unreviewed]SubName: Full=UGCGL2 protein {ECO:0000313|EMBL:AAH17759.1}; Flags: Fragment;+++[Q08AC9_HUMAN|Unreviewed]SubName: Full=UGCGL2 protein {ECO:0000313|EMBL:AAI25235.1};+++[Q2TAA6_HUMAN|Unreviewed]SubName: Full=UGCGL2 protein {ECO:0000313|EMBL:AAI11022.1};+++[Q6NVZ4_HUMAN|Unreviewed]SubName: Full=UGCGL2 protein {ECO:0000313|EMBL:AAH67807.1};"]
[55771,"'PRR11'",18.15,20,19.075,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005634///nucleus",null,"GO:0007050///cell cycle arrest+++GO:0051726///regulation of cell cycle",null,"[PRR11_HUMAN|Reviewed]RecName: Full=Proline-rich protein 11;+++[D2SNZ4_HUMAN|Unreviewed]SubName: Full=Proline rich 11, isoform CRA_a {ECO:0000313|EMBL:EAW94416.1}; SubName: Full=Transcription repressor of MHCII {ECO:0000313|EMBL:ACL14948.1};+++[J3QKY4_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 11 {ECO:0000313|Ensembl:ENSP00000463292}; Flags: Fragment;+++[J3QQS2_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 11 {ECO:0000313|Ensembl:ENSP00000463871}; Flags: Fragment;+++[J3QR53_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 11 {ECO:0000313|Ensembl:ENSP00000464048}; Flags: Fragment;+++[J3QRV0_HUMAN|Unreviewed]SubName: Full=Proline-rich protein 11 {ECO:0000313|Ensembl:ENSP00000464392}; Flags: Fragment;"]
[55789,"'DEPDC1B'",6,2,4,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0070552///BRISC complex+++GO:0005654///nucleoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0070531///BRCA1-A complex+++GO:0000922///spindle pole+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000152///nuclear ubiquitin ligase complex","GO:0016787///hydrolase activity+++GO:0031593///polyubiquitin modification-dependent protein binding+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0061578///Lys63-specific deubiquitinase activity+++GO:0005515///protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0030234///enzyme regulator activity+++GO:0008233///peptidase activity+++GO:0008237///metallopeptidase activity+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding","GO:0035556///intracellular signal transduction+++GO:0045739///positive regulation of DNA repair+++GO:0051301///cell division+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0050790///regulation of catalytic activity+++GO:0006281///DNA repair+++GO:0016477///cell migration+++GO:0010165///response to X-ray+++GO:0072425///signal transduction involved in G2 DNA damage checkpoint+++GO:0006325///chromatin organization+++GO:0070537///histone H2A K63-linked deubiquitination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0010212///response to ionizing radiation+++GO:0007165///signal transduction+++GO:0006302///double-strand break repair+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0043547///positive regulation of GTPase activity+++GO:0006508///proteolysis+++GO:0070536///protein K63-linked deubiquitination+++GO:0016579///protein deubiquitination+++GO:0007049///cell cycle","IPR000198///Rho GTPase-activating protein domain+++IPR008936///Rho GTPase activation protein+++IPR000591///DEP domain+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR036388///Winged helix-like DNA-binding domain superfamily","[DEP1B_HUMAN|Reviewed]RecName: Full=DEP domain-containing protein 1B; AltName: Full=HBV X-transactivated gene 8 protein; AltName: Full=HBV XAg-transactivated protein 8;+++[A0A2X0SFC1_HUMAN|Unreviewed]SubName: Full=DEPDC1B {ECO:0000313|EMBL:SPT35738.1}; Flags: Fragment;+++[D6RDV9_HUMAN|Unreviewed]SubName: Full=DEP domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000426979};+++[D6RIB0_HUMAN|Unreviewed]SubName: Full=DEP domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000427527};"]
[55805,"'LRP2BP'",28.14,49,38.57,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm","GO:0005515///protein binding",null,"IPR013026///Tetratricopeptide repeat-containing domain+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR006597///Sel1-like repeat+++IPR019734///Tetratricopeptide repeat","[LR2BP_HUMAN|Reviewed]RecName: Full=LRP2-binding protein; AltName: Full=Megalin-binding protein; Short=MegBP;+++[D6RGF6_HUMAN|Unreviewed]SubName: Full=LRP2-binding protein {ECO:0000313|Ensembl:ENSP00000421244}; Flags: Fragment;+++[G5E9Z9_HUMAN|Unreviewed]SubName: Full=LRP2 binding protein, isoform CRA_a {ECO:0000313|EMBL:EAX04649.1}; SubName: Full=LRP2-binding protein {ECO:0000313|Ensembl:ENSP00000424610};"]
[55825,"'PECR'",10,20,15,"04146///Peroxisome+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism",null,null,"R07761///octadecanoyl-CoA:NADP+ trans-2-oxidoreductase   (2E)-Octadecenoyl-CoA + NADPH + H+ <=> Stearoyl-CoA + NADP+","GO:0005778///peroxisomal membrane+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005777///peroxisome","GO:0005102///signaling receptor binding+++GO:0016491///oxidoreductase activity+++GO:0008670///2,4-dienoyl-CoA reductase (NADPH) activity+++GO:0019166///trans-2-enoyl-CoA reductase (NADPH) activity","GO:0033306///phytol metabolic process+++GO:0001561///fatty acid alpha-oxidation+++GO:0006625///protein targeting to peroxisome+++GO:0006633///fatty acid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0055114///oxidation-reduction process+++GO:0006631///fatty acid metabolic process","IPR036291///NAD(P)-binding domain superfamily+++IPR002347///Short-chain dehydrogenase/reductase SDR","[PECR_HUMAN|Reviewed]RecName: Full=Peroxisomal trans-2-enoyl-CoA reductase; Short=TERP; EC=1.3.1.38; AltName: Full=2,4-dienoyl-CoA reductase-related protein; Short=DCR-RP; AltName: Full=HPDHase; AltName: Full=Short chain dehydrogenase/reductase family 29C member 1; AltName: Full=pVI-ARL;+++[B4DJS2_HUMAN|Unreviewed]SubName: Full=Peroxisomal trans-2-enoyl-CoA reductase {ECO:0000313|Ensembl:ENSP00000395512}; SubName: Full=cDNA FLJ55082, highly similar to Peroxisomal trans-2-enoyl-CoA reductase {ECO:0000313|EMBL:BAG58934.1};"]
[55846,"'ITFG2'",322,298,310,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04218///Cellular senescence+++04915///Estrogen signaling pathway","H01646///Major depressive disorder (MDD)",null,null,"GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0005829///cytosol+++GO:0140007///KICSTOR complex","GO:0005524///ATP binding+++GO:0051219///phosphoprotein binding+++GO:0031072///heat shock protein binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0035259///glucocorticoid receptor binding+++GO:0005528///FK506 binding+++GO:0030674///protein binding, bridging+++GO:0005525///GTP binding+++GO:0048156///tau protein binding+++GO:0003723///RNA binding+++GO:0032767///copper-dependent protein binding","GO:0042149///cellular response to glucose starvation+++GO:0007229///integrin-mediated signaling pathway+++GO:0002314///germinal center B cell differentiation+++GO:1904262///negative regulation of TORC1 signaling+++GO:0034198///cellular response to amino acid starvation","IPR036322///WD40-repeat-containing domain superfamily+++IPR031793///Integrin-alpha FG-GAP repeat-containing protein 2","[ITFG2_HUMAN|Reviewed]RecName: Full=KICSTOR complex protein ITFG2 {ECO:0000305}; AltName: Full=Integrin-alpha FG-GAP repeat-containing protein 2 {ECO:0000312|HGNC:HGNC:30879};+++[A0A0S2Z5G6_HUMAN|Unreviewed]SubName: Full=Integrin alpha FG-GAP repeat containing 2 isoform 2 {ECO:0000313|EMBL:ALQ34178.1};+++[A0A0S2Z5L6_HUMAN|Unreviewed]SubName: Full=Integrin alpha FG-GAP repeat containing 2 isoform 3 {ECO:0000313|EMBL:ALQ34179.1};+++[A0A0S2Z5P1_HUMAN|Unreviewed]SubName: Full=Integrin alpha FG-GAP repeat containing 2 isoform 1 {ECO:0000313|EMBL:ALQ34177.1}; Flags: Fragment;+++[A0A2R8Y7E0_HUMAN|Unreviewed]SubName: Full=KICSTOR complex protein ITFG2 {ECO:0000313|Ensembl:ENSP00000496213};+++[F5H1D0_HUMAN|Unreviewed]SubName: Full=Integrin alpha FG-GAP repeat containing 2 isoform 4 {ECO:0000313|EMBL:ALQ34180.1}; SubName: Full=KICSTOR complex protein ITFG2 {ECO:0000313|Ensembl:ENSP00000445769};+++[H0YFM4_HUMAN|Unreviewed]SubName: Full=KICSTOR complex protein ITFG2 {ECO:0000313|Ensembl:ENSP00000439324}; Flags: Fragment;+++[H0YG72_HUMAN|Unreviewed]SubName: Full=KICSTOR complex protein ITFG2 {ECO:0000313|Ensembl:ENSP00000442023}; Flags: Fragment;+++[H0YGR0_HUMAN|Unreviewed]SubName: Full=KICSTOR complex protein ITFG2 {ECO:0000313|Ensembl:ENSP00000444331}; Flags: Fragment;"]
[55862,"'ECHDC1'",321,349,335,"00640///Propanoate metabolism",null,null,"R00923///(S)-methylmalonyl-CoA carboxy-lyase (propanoyl-CoA-forming)   (S)-Methylmalonyl-CoA <=> Propanoyl-CoA + CO2","GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0004300///enoyl-CoA hydratase activity+++GO:0016831///carboxy-lyase activity+++GO:0016829///lyase activity+++GO:0003824///catalytic activity","GO:0006635///fatty acid beta-oxidation","IPR001753///Enoyl-CoA hydratase/isomerase+++IPR018376///Enoyl-CoA hydratase/isomerase, conserved site+++IPR029045///ClpP/crotonase-like domain superfamily","[ECHD1_HUMAN|Reviewed]RecName: Full=Ethylmalonyl-CoA decarboxylase; EC=4.1.1.94; AltName: Full=Enoyl-CoA hydratase domain-containing protein 1; AltName: Full=Methylmalonyl-CoA decarboxylase; Short=MMCD; EC=4.1.1.41;+++[E9PIU8_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000433874};+++[E9PJS8_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000435502}; Flags: Fragment;+++[E9PLY6_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000435068}; Flags: Fragment;+++[E9PPG7_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000420711};+++[E9PRU6_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000434143}; Flags: Fragment;+++[F2Z2D6_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000436703};+++[H0Y525_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000396096}; Flags: Fragment;+++[H0Y5L2_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000399233}; Flags: Fragment;+++[H0YCS9_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000432265}; Flags: Fragment;+++[H0YD54_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000433015}; Flags: Fragment;+++[J3KP84_HUMAN|Unreviewed]SubName: Full=Ethylmalonyl-CoA decarboxylase {ECO:0000313|Ensembl:ENSP00000357278};"]
[55897,"'MESP1'",4,7,5.5,null,"H00517///Spondylocostal dysostosis (SCD)",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0035326///enhancer binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0070368///positive regulation of hepatocyte differentiation+++GO:0060913///cardiac cell fate determination+++GO:0035481///positive regulation of Notch signaling pathway involved in heart induction+++GO:0042662///negative regulation of mesodermal cell fate specification+++GO:0045446///endothelial cell differentiation+++GO:0007219///Notch signaling pathway+++GO:0060975///cardioblast migration to the midline involved in heart field formation+++GO:0001756///somitogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0048368///lateral mesoderm development+++GO:0003236///sinus venosus morphogenesis+++GO:0060921///sinoatrial node cell differentiation+++GO:0003007///heart morphogenesis+++GO:0003241///growth involved in heart morphogenesis+++GO:0022008///neurogenesis+++GO:0007275///multicellular organism development+++GO:0001947///heart looping+++GO:0003139///secondary heart field specification+++GO:0003210///cardiac atrium formation+++GO:0023019///signal transduction involved in regulation of gene expression+++GO:0003259///cardioblast anterior-lateral migration+++GO:0003143///embryonic heart tube morphogenesis+++GO:0008078///mesodermal cell migration+++GO:0090082///positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway+++GO:0003260///cardioblast migration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0003211///cardiac ventricle formation+++GO:0055007///cardiac muscle cell differentiation+++GO:0051155///positive regulation of striated muscle cell differentiation+++GO:0007369///gastrulation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0042664///negative regulation of endodermal cell fate specification+++GO:0060947///cardiac vascular smooth muscle cell differentiation","IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain","[MESP1_HUMAN|Reviewed]RecName: Full=Mesoderm posterior protein 1; AltName: Full=Class C basic helix-loop-helix protein 5; Short=bHLHc5;"]
[55917,"'CTTNBP2NL'",819,1076,947.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton","GO:0051721///protein phosphatase 2A binding+++GO:0005515///protein binding","GO:0032410///negative regulation of transporter activity+++GO:0006470///protein dephosphorylation+++GO:0034763///negative regulation of transmembrane transport","IPR019131///Cortactin-binding protein-2, N-terminal","[CT2NL_HUMAN|Reviewed]RecName: Full=CTTNBP2 N-terminal-like protein;+++[A0A024R0C7_HUMAN|Unreviewed]SubName: Full=CTTNBP2 N-terminal like, isoform CRA_b {ECO:0000313|EMBL:EAW56517.1};+++[B1AMN7_HUMAN|Unreviewed]SubName: Full=CTTNBP2 N-terminal-like protein {ECO:0000313|Ensembl:ENSP00000390976}; Flags: Fragment;"]
[5596,"'MAPK4'",22,17,19.5,"04657///IL-17 signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0004707///MAP kinase activity+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0042803///protein homodimerization activity+++GO:0004672///protein kinase activity+++GO:0046982///protein heterodimerization activity+++GO:0019901///protein kinase binding+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0035556///intracellular signal transduction+++GO:0007049///cell cycle+++GO:0010468///regulation of gene expression+++GO:0000165///MAPK cascade+++GO:0071310///cellular response to organic substance+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site+++IPR008350///Mitogen-activated protein (MAP) kinase, ERK3/4","[MK04_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase 4; Short=MAP kinase 4; Short=MAPK 4; EC=2.7.11.24; AltName: Full=Extracellular signal-regulated kinase 4; Short=ERK-4; AltName: Full=MAP kinase isoform p63; Short=p63-MAPK;+++[B4DEW2_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 4 {ECO:0000313|Ensembl:ENSP00000439231}; SubName: Full=cDNA FLJ50121, highly similar to Homo sapiens mitogen-activated protein kinase 4 (MAPK4), mRNA {ECO:0000313|EMBL:BAG57223.1};+++[K7ELV1_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 4 {ECO:0000313|Ensembl:ENSP00000466233};+++[K7EN18_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 4 {ECO:0000313|Ensembl:ENSP00000465661};"]
[5600,"'MAPK11'",281,233,257,"04550///Signaling pathways regulating pluripotency of stem cells+++04912///GnRH signaling pathway+++04380///Osteoclast differentiation+++05152///Tuberculosis+++04010///MAPK signaling pathway+++05140///Leishmaniasis+++04714///Thermogenesis+++04139///Mitophagy - yeast+++04933///AGE-RAGE signaling pathway in diabetic complications+++04926///Relaxin signaling pathway+++04622///RIG-I-like receptor signaling pathway+++04015///Rap1 signaling pathway+++05163///Human cytomegalovirus infection+++05160///Hepatitis C+++05133///Pertussis+++04670///Leukocyte transendothelial migration+++04722///Neurotrophin signaling pathway+++05169///Epstein-Barr virus infection+++04660///T cell receptor signaling pathway+++04668///TNF signaling pathway+++01522///Endocrine resistance+++04620///Toll-like receptor signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04068///FoxO signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04750///Inflammatory mediator regulation of TRP channels+++04914///Progesterone-mediated oocyte maturation+++05145///Toxoplasmosis+++04013///MAPK signaling pathway - fly+++04621///NOD-like receptor signaling pathway+++04728///Dopaminergic synapse+++04218///Cellular senescence+++05142///Chagas disease (American trypanosomiasis)+++04625///C-type lectin receptor signaling pathway+++04370///VEGF signaling pathway+++04917///Prolactin signaling pathway+++05164///Influenza A+++04212///Longevity regulating pathway - worm+++04011///MAPK signaling pathway - yeast+++04611///Platelet activation+++04664///Fc epsilon RI signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04659///Th17 cell differentiation+++04071///Sphingolipid signaling pathway+++04658///Th1 and Th2 cell differentiation+++05132///Salmonella infection+++04723///Retrograde endocannabinoid signaling+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05014///Amyotrophic lateral sclerosis (ALS)+++05131///Shigellosis+++04624///Toll and Imd signaling pathway+++05205///Proteoglycans in cancer+++04657///IL-17 signaling pathway",null,"M00689///MAPK (p38) signaling",null,"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0004707///MAP kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0010468///regulation of gene expression+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0051403///stress-activated MAPK cascade+++GO:0010628///positive regulation of gene expression+++GO:0071310///cellular response to organic substance+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0071347///cellular response to interleukin-1+++GO:0006468///protein phosphorylation+++GO:2001184///positive regulation of interleukin-12 secretion+++GO:0060043///regulation of cardiac muscle cell proliferation+++GO:0060044///negative regulation of cardiac muscle cell proliferation+++GO:0000187///activation of MAPK activity+++GO:0051149///positive regulation of muscle cell differentiation","IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR003527///Mitogen-activated protein (MAP) kinase, conserved site+++IPR008352///Mitogen-activated protein (MAP) kinase p38-like+++IPR017441///Protein kinase, ATP binding site","[MK11_HUMAN|Reviewed]RecName: Full=Mitogen-activated protein kinase 11; Short=MAP kinase 11; Short=MAPK 11; EC=2.7.11.24; AltName: Full=Mitogen-activated protein kinase p38 beta; Short=MAP kinase p38 beta; Short=p38b; AltName: Full=Stress-activated protein kinase 2b; Short=SAPK2b; AltName: Full=p38-2;+++[F8WDP4_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase 11 {ECO:0000313|Ensembl:ENSP00000409136};"]
[5607,"'MAP2K5'",357,473,415,"04540///Gap junction+++04010///MAPK signaling pathway+++04722///Neurotrophin signaling pathway+++05418///Fluid shear stress and atherosclerosis+++04921///Oxytocin signaling pathway",null,"M00690///MAPK (ERK5) signaling",null,"GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0004672///protein kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0004708///MAP kinase kinase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding","GO:0051247///positive regulation of protein metabolic process+++GO:0000187///activation of MAPK activity+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0000165///MAPK cascade+++GO:0070375///ERK5 cascade+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0016310///phosphorylation+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0006468///protein phosphorylation+++GO:0032147///activation of protein kinase activity+++GO:0007507///heart development+++GO:2001240///negative regulation of extrinsic apoptotic signaling pathway in absence of ligand+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production+++GO:0045415///negative regulation of interleukin-8 biosynthetic process+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0007165///signal transduction+++GO:0071363///cellular response to growth factor stimulus+++GO:0023014///signal transduction by protein phosphorylation+++GO:0030307///positive regulation of cell growth","IPR011009///Protein kinase-like domain superfamily+++IPR034851///Dual specificity mitogen-activated protein kinase kinase 5, PB1 domain+++IPR000270///PB1 domain+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site","[MP2K5_HUMAN|Reviewed]RecName: Full=Dual specificity mitogen-activated protein kinase kinase 5; Short=MAP kinase kinase 5; Short=MAPKK 5; EC=2.7.12.2; AltName: Full=MAPK/ERK kinase 5; Short=MEK 5;+++[A0A024R5X5_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase 5, isoform CRA_b {ECO:0000313|EMBL:EAW77802.1};+++[A0A024R5Y2_HUMAN|Unreviewed]SubName: Full=Mitogen-activated protein kinase kinase 5, isoform CRA_a {ECO:0000313|EMBL:EAW77801.1};+++[A0A087WWX7_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 5 {ECO:0000313|Ensembl:ENSP00000480580}; Flags: Fragment;+++[A0A087X0Z8_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 5 {ECO:0000313|Ensembl:ENSP00000483771}; Flags: Fragment;+++[A6NK28_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 5 {ECO:0000313|Ensembl:ENSP00000342101};+++[H7BZL1_HUMAN|Unreviewed]SubName: Full=Dual-specificity mitogen-activated protein kinase kinase 5 {ECO:0000313|Ensembl:ENSP00000390196}; Flags: Fragment;"]
[56108,"'PCDHGA7'",110.62,189.39,150.005,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0005509///calcium ion binding","GO:0007155///cell adhesion+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules","IPR013164///Cadherin, N-terminal+++IPR032455///Cadherin, cytoplasmic C-terminal domain+++IPR031904///Cadherin, C-terminal catenin-binding domain+++IPR015919///Cadherin-like superfamily+++IPR020894///Cadherin conserved site+++IPR002126///Cadherin-like","[PCDG7_HUMAN|Reviewed]RecName: Full=Protocadherin gamma-A7; Short=PCDH-gamma-A7; Flags: Precursor;"]
[56128,"'PCDHB8'",41.01,69.34,55.175,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","IPR013164///Cadherin, N-terminal+++IPR002126///Cadherin-like+++IPR032455///Cadherin, cytoplasmic C-terminal domain+++IPR020894///Cadherin conserved site+++IPR015919///Cadherin-like superfamily","[PCDB8_HUMAN|Reviewed]RecName: Full=Protocadherin beta-8 {ECO:0000305}; Short=PCDH-beta-8 {ECO:0000305}; AltName: Full=Protocadherin-3I; Flags: Precursor;"]
[56144,"'PCDHA4'",34.19,33.4,33.795,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0030424///axon+++GO:0098982///GABA-ergic synapse+++GO:0032592///integral component of mitochondrial membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0099056///integral component of presynaptic membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0098978///glutamatergic synapse+++GO:0042734///presynaptic membrane+++GO:0098793///presynapse+++GO:0030426///growth cone+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane","GO:0099635///voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels+++GO:0004930///G protein-coupled receptor activity+++GO:0008144///drug binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0005509///calcium ion binding+++GO:0004949///cannabinoid receptor activity+++GO:0046872///metal ion binding","GO:0007613///memory+++GO:0010976///positive regulation of neuron projection development+++GO:0098921///retrograde trans-synaptic signaling by endocannabinoid+++GO:0002866///positive regulation of acute inflammatory response to antigenic stimulus+++GO:0007155///cell adhesion+++GO:0007283///spermatogenesis+++GO:0050796///regulation of insulin secretion+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0042220///response to cocaine+++GO:0032228///regulation of synaptic transmission, GABAergic+++GO:0007399///nervous system development+++GO:0007611///learning or memory+++GO:0031999///negative regulation of fatty acid beta-oxidation+++GO:0099553///trans-synaptic signaling by endocannabinoid, modulating synaptic transmission+++GO:0060259///regulation of feeding behavior+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0038171///cannabinoid signaling pathway+++GO:0060405///regulation of penile erection+++GO:0007584///response to nutrient+++GO:0051966///regulation of synaptic transmission, glutamatergic+++GO:0007568///aging+++GO:0032496///response to lipopolysaccharide+++GO:0033004///negative regulation of mast cell activation+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0045759///negative regulation of action potential+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007165///signal transduction+++GO:0033602///negative regulation of dopamine secretion+++GO:0045776///negative regulation of blood pressure+++GO:0045471///response to ethanol+++GO:0045777///positive regulation of blood pressure+++GO:0099703///induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration+++GO:0031622///positive regulation of fever generation+++GO:0019233///sensory perception of pain+++GO:0007413///axonal fasciculation+++GO:0019216///regulation of lipid metabolic process+++GO:0099533///positive regulation of presynaptic cytosolic calcium concentration+++GO:0042593///glucose homeostasis+++GO:0043271///negative regulation of ion transport+++GO:0060135///maternal process involved in female pregnancy+++GO:0043065///positive regulation of apoptotic process+++GO:0051001///negative regulation of nitric-oxide synthase activity+++GO:0035094///response to nicotine+++GO:0043278///response to morphine","IPR020894///Cadherin conserved site+++IPR015919///Cadherin-like superfamily+++IPR031904///Cadherin, C-terminal catenin-binding domain+++IPR002126///Cadherin-like+++IPR013164///Cadherin, N-terminal","[PCDA4_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-4 {ECO:0000305}; Short=PCDH-alpha-4 {ECO:0000305}; Flags: Precursor;+++[A0A087WSW8_HUMAN|Unreviewed]SubName: Full=Protocadherin alpha-4 {ECO:0000313|Ensembl:ENSP00000367365};+++[D6RA20_HUMAN|Unreviewed]SubName: Full=Protocadherin alpha-4 {ECO:0000313|Ensembl:ENSP00000423470};+++[F8W187_HUMAN|Unreviewed]SubName: Full=Cannabinoid receptor 1 {ECO:0000313|Ensembl:ENSP00000446702}; Flags: Fragment;+++[F8W908_HUMAN|Unreviewed]SubName: Full=Cannabinoid receptor 1 {ECO:0000313|Ensembl:ENSP00000355418};+++[Q59H34_HUMAN|Unreviewed]SubName: Full=Protocadherin alpha 4 isoform 1 variant {ECO:0000313|EMBL:BAD92162.1}; Flags: Fragment;+++[Q9BYY6_HUMAN|Unreviewed]SubName: Full=Cannabinoid receptor 1 {ECO:0000313|EMBL:AAG37765.1}; Flags: Fragment;"]
[5623,"'PSPN'",11,3,7,{"$nulls":4},"GO:0005576///extracellular region","GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0005102///signaling receptor binding+++GO:0008083///growth factor activity","GO:0000165///MAPK cascade+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:0007417///central nervous system development+++GO:0010469///regulation of signaling receptor activity","IPR001839///Transforming growth factor-beta, C-terminal+++IPR029034///Cystine-knot cytokine","[PSPN_HUMAN|Reviewed]RecName: Full=Persephin; Short=PSP; Flags: Precursor;+++[M0QYK2_HUMAN|Unreviewed]SubName: Full=Persephin {ECO:0000313|Ensembl:ENSP00000469884};"]
[56262,"'LRRC8A'",3147,3151,3149,null,"H00085///Agammaglobulinemias",null,null,"GO:0009986///cell surface+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0034702///ion channel complex+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005253///anion channel activity+++GO:0005225///volume-sensitive anion channel activity+++GO:0042802///identical protein binding","GO:0030154///cell differentiation+++GO:0034214///protein hexamerization+++GO:0006820///anion transport+++GO:0015734///taurine transport+++GO:0055085///transmembrane transport+++GO:0002329///pre-B cell differentiation+++GO:0006970///response to osmotic stress+++GO:0006811///ion transport+++GO:0015698///inorganic anion transport+++GO:0098656///anion transmembrane transport+++GO:0015810///aspartate transmembrane transport+++GO:0006884///cell volume homeostasis","IPR021040///LRRC8, pannexin-like TM region+++IPR003591///Leucine-rich repeat, typical subtype+++IPR038960///LRRC8+++IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily","[LRC8A_HUMAN|Reviewed]RecName: Full=Volume-regulated anion channel subunit LRRC8A; AltName: Full=Leucine-rich repeat-containing protein 8A; AltName: Full=Swelling protein 1;+++[A0A024R892_HUMAN|Unreviewed]SubName: Full=Leucine rich repeat containing 8 family, member A, isoform CRA_a {ECO:0000313|EMBL:EAW87843.1};+++[A8K1C7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75179, highly similar to Homo sapiens leucine rich repeat containing 8 family, member A, mRNA {ECO:0000313|EMBL:BAF82531.1};"]
[56342,"'PPAN'",224.5,182.76,203.63,{"$nulls":4},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0030687///preribosome, large subunit precursor","GO:0019843///rRNA binding+++GO:0003723///RNA binding","GO:0000027///ribosomal large subunit assembly","IPR007109///Brix domain","[SSF1_HUMAN|Reviewed]RecName: Full=Suppressor of SWI4 1 homolog; Short=Ssf-1; AltName: Full=Brix domain-containing protein 3; AltName: Full=Peter Pan homolog;+++[A8MV53_HUMAN|Unreviewed]SubName: Full=HCG2033702, isoform CRA_a {ECO:0000313|EMBL:EAW84073.1}; SubName: Full=Suppressor of SWI4 1 homolog {ECO:0000313|Ensembl:ENSP00000377382};+++[C9J3W3_HUMAN|Unreviewed]SubName: Full=Suppressor of SWI4 1 homolog {ECO:0000313|Ensembl:ENSP00000410485}; Flags: Fragment;+++[C9JHF7_HUMAN|Unreviewed]SubName: Full=Suppressor of SWI4 1 homolog {ECO:0000313|Ensembl:ENSP00000415988}; Flags: Fragment;+++[H7C446_HUMAN|Unreviewed]SubName: Full=Suppressor of SWI4 1 homolog {ECO:0000313|Ensembl:ENSP00000415467}; Flags: Fragment;"]
[5652,"'PRSS8'",93,73,83,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0046658///anchored component of plasma membrane+++GO:0016020///membrane+++GO:0019897///extrinsic component of plasma membrane","GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0017080///sodium channel regulator activity+++GO:0008236///serine-type peptidase activity+++GO:0005515///protein binding+++GO:0008233///peptidase activity+++GO:0004252///serine-type endopeptidase activity","GO:0006508///proteolysis+++GO:0010765///positive regulation of sodium ion transport+++GO:0070268///cornification","IPR033116///Serine proteases, trypsin family, serine active site+++IPR001254///Serine proteases, trypsin domain+++IPR001314///Peptidase S1A, chymotrypsin family+++IPR018114///Serine proteases, trypsin family, histidine active site+++IPR009003///Peptidase S1, PA clan","[PRSS8_HUMAN|Reviewed]RecName: Full=Prostasin; EC=3.4.21.-; AltName: Full=Channel-activating protease 1; Short=CAP1; AltName: Full=Serine protease 8; Contains: RecName: Full=Prostasin light chain; Contains: RecName: Full=Prostasin heavy chain; Flags: Precursor;+++[H3BUJ8_HUMAN|Unreviewed]SubName: Full=Prostasin {ECO:0000313|Ensembl:ENSP00000457673}; Flags: Fragment;+++[H3BVC8_HUMAN|Unreviewed]SubName: Full=Prostasin {ECO:0000313|Ensembl:ENSP00000458056}; Flags: Fragment;"]
[56624,"'ASAH2'",22.97,12.92,17.945,"04071///Sphingolipid signaling pathway+++00600///Sphingolipid metabolism+++01100///Metabolic pathways",null,"M00099///Sphingosine biosynthesis","R01494///N-Acylsphingosine amidohydrolase   N-Acylsphingosine + H2O <=> Fatty acid + Sphingosine","GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion","GO:0016787///hydrolase activity+++GO:0008270///zinc ion binding+++GO:0102121///ceramidase activity+++GO:0046872///metal ion binding+++GO:0017040///N-acylsphingosine amidohydrolase activity+++GO:0005509///calcium ion binding","GO:0042759///long-chain fatty acid biosynthetic process+++GO:0010033///response to organic substance+++GO:0006915///apoptotic process+++GO:0006672///ceramide metabolic process+++GO:0006665///sphingolipid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006670///sphingosine metabolic process+++GO:0046512///sphingosine biosynthetic process+++GO:0046514///ceramide catabolic process","IPR006823///Neutral/alkaline nonlysosomal ceramidase+++IPR031331///Neutral/alkaline non-lysosomal ceramidase, C-terminal+++IPR038445///Neutral ceramidase, C-terminal domain superfamily+++IPR031329///Neutral/alkaline non-lysosomal ceramidase, N-terminal","[ASAH2_HUMAN|Reviewed]RecName: Full=Neutral ceramidase; Short=N-CDase; Short=NCDase; EC=3.5.1.23 {ECO:0000269|PubMed:10781606, ECO:0000269|PubMed:16229686, ECO:0000269|PubMed:26190575}; AltName: Full=Acylsphingosine deacylase 2; AltName: Full=BCDase; AltName: Full=LCDase; Short=hCD; AltName: Full=N-acylsphingosine amidohydrolase 2; AltName: Full=Non-lysosomal ceramidase; Contains: RecName: Full=Neutral ceramidase soluble form;+++[A0A0C4DFQ8_HUMAN|Unreviewed]SubName: Full=Neutral ceramidase {ECO:0000313|Ensembl:ENSP00000329886};+++[E9PBM9_HUMAN|Unreviewed]SubName: Full=Neutral ceramidase {ECO:0000313|Ensembl:ENSP00000392766};+++[V9GY52_HUMAN|Unreviewed]SubName: Full=Neutral ceramidase {ECO:0000313|Ensembl:ENSP00000476403}; Flags: Fragment;+++[V9GYJ5_HUMAN|Unreviewed]SubName: Full=Neutral ceramidase {ECO:0000313|Ensembl:ENSP00000476827}; Flags: Fragment;"]
[56674,"'TMEM9B'",484,578,531,{"$nulls":4},"GO:0016020///membrane+++GO:0031901///early endosome membrane+++GO:0005765///lysosomal membrane+++GO:0005768///endosome+++GO:0016021///integral component of membrane+++GO:0005764///lysosome",null,"GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling","IPR008853///TMEM9","[TMM9B_HUMAN|Reviewed]RecName: Full=Transmembrane protein 9B; Flags: Precursor;+++[B7Z6P5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51099, highly similar to Transmembrane protein 9B {ECO:0000313|EMBL:BAH13331.1};+++[E9PMI7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 9B {ECO:0000313|Ensembl:ENSP00000434961}; Flags: Fragment;+++[E9PR12_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 9B {ECO:0000313|Ensembl:ENSP00000432373};+++[L8E8Z8_HUMAN|Unreviewed]SubName: Full=Alternative protein TMEM9B {ECO:0000313|EMBL:CCQ43639.1};+++[Q543A1_HUMAN|Unreviewed]SubName: Full=Putative NFkB activating protein {ECO:0000313|EMBL:BAC77370.1}; SubName: Full=TMEM9 domain family, member B, isoform CRA_a {ECO:0000313|EMBL:EAW68607.1}; SubName: Full=cDNA FLJ90196 fis, clone MAMMA1001344 {ECO:0000313|EMBL:BAC11131.1}; SubName: Full=cDNA, FLJ93544 {ECO:0000313|EMBL:BAG35894.1};"]
[5680,"'PSG11'",1,3.15,2.075,{"$nulls":4},"GO:0005576///extracellular region",null,"GO:0007565///female pregnancy","IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013106///Immunoglobulin V-set domain+++IPR003598///Immunoglobulin subtype 2+++IPR003599///Immunoglobulin subtype","[PSG11_HUMAN|Reviewed]RecName: Full=Pregnancy-specific beta-1-glycoprotein 11; Short=PS-beta-G-11; Short=PSBG-11; Short=Pregnancy-specific glycoprotein 11; AltName: Full=Pregnancy-specific beta-1-glycoprotein 13; Short=PS-beta-G-13; Short=PSBG-13; Short=Pregnancy-specific glycoprotein 13; Flags: Precursor;+++[A0A024R0L9_HUMAN|Unreviewed]SubName: Full=Pregnancy specific beta-1-glycoprotein 11, isoform CRA_a {ECO:0000313|EMBL:EAW57167.1};+++[M0R276_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 11 {ECO:0000313|Ensembl:ENSP00000472372}; Flags: Fragment;+++[M0R2P9_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 11 {ECO:0000313|Ensembl:ENSP00000472717};+++[Q12810_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein {ECO:0000313|EMBL:AAA78263.1}; Flags: Fragment;+++[Q12812_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1-glycoprotein 11 C-R domain {ECO:0000313|EMBL:AAA78265.1}; Flags: Fragment;+++[Q15461_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific beta-1 glycoprotein-11 {ECO:0000313|EMBL:AAA78805.1}; Flags: Fragment;+++[Q9UMH8_HUMAN|Unreviewed]SubName: Full=Pregnancy-specific glycoprotein {ECO:0000313|EMBL:AAA18432.1}; Flags: Fragment;"]
[5686,"'PSMA5'",613,460,536.5,"03050///Proteasome",null,"M00340///Proteasome, 20S core particle+++M00337///Immunoproteasome",null,"GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0005576///extracellular region+++GO:0000502///proteasome complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:1904813///ficolin-1-rich granule lumen+++GO:0005839///proteasome core complex+++GO:0034774///secretory granule lumen+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0010498///proteasomal protein catabolic process+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0006508///proteolysis+++GO:0043312///neutrophil degranulation+++GO:0043687///post-translational protein modification+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination","IPR023332///Proteasome alpha-type subunit+++IPR001353///Proteasome, subunit alpha/beta+++IPR033812///Proteasome subunit alpha5+++IPR029055///Nucleophile aminohydrolases, N-terminal+++IPR000426///Proteasome alpha-subunit, N-terminal domain","[PSA5_HUMAN|Reviewed]RecName: Full=Proteasome subunit alpha type-5; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=Macropain zeta chain; AltName: Full=Multicatalytic endopeptidase complex zeta chain; AltName: Full=Proteasome zeta chain;+++[A0A109NGN6_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};"]
[5687,"'PSMA6'",738,701,719.5,"03050///Proteasome",null,"M00337///Immunoproteasome+++M00340///Proteasome, 20S core particle",null,"GO:0005829///cytosol+++GO:0000932///P-body+++GO:0019773///proteasome core complex, alpha-subunit complex+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0030016///myofibril+++GO:0005654///nucleoplasm+++GO:0005839///proteasome core complex+++GO:0005844///polysome+++GO:0070062///extracellular exosome+++GO:0000502///proteasome complex+++GO:0005634///nucleus+++GO:0030017///sarcomere","GO:0051059///NF-kappaB binding+++GO:0003723///RNA binding+++GO:0035639///purine ribonucleoside triphosphate binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0004175///endopeptidase activity+++GO:0004298///threonine-type endopeptidase activity+++GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0006508///proteolysis+++GO:0050727///regulation of inflammatory response+++GO:0010498///proteasomal protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0016579///protein deubiquitination+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0006511///ubiquitin-dependent protein catabolic process","IPR029055///Nucleophile aminohydrolases, N-terminal+++IPR000426///Proteasome alpha-subunit, N-terminal domain+++IPR023332///Proteasome alpha-type subunit+++IPR034642///Proteasome subunit alpha6+++IPR001353///Proteasome, subunit alpha/beta","[PSA6_HUMAN|Reviewed]RecName: Full=Proteasome subunit alpha type-6; EC=3.4.25.1 {ECO:0000269|PubMed:27176742}; AltName: Full=27 kDa prosomal protein; Short=PROS-27; Short=p27K; AltName: Full=Macropain iota chain; AltName: Full=Multicatalytic endopeptidase complex iota chain; AltName: Full=Proteasome iota chain;+++[A0A140VK44_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V295_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V2S7_HUMAN|Unreviewed]SubName: Full=Proteasome subunit alpha type-6 {ECO:0000313|Ensembl:ENSP00000450844};+++[G3V3I1_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V3U4_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[G3V4S5_HUMAN|Unreviewed]SubName: Full=Proteasome subunit alpha type-6 {ECO:0000313|Ensembl:ENSP00000451958};+++[G3V5Z7_HUMAN|Unreviewed]RecName: Full=Proteasome subunit alpha type {ECO:0000256|RuleBase:RU000551}; EC=3.4.25.1 {ECO:0000256|RuleBase:RU000551};+++[H0YJC4_HUMAN|Unreviewed]SubName: Full=Proteasome subunit alpha type-6 {ECO:0000313|Ensembl:ENSP00000451171}; Flags: Fragment;+++[Q9BZ93_HUMAN|Unreviewed]SubName: Full=Prosomal P27K protein {ECO:0000313|EMBL:AAG61139.1}; Flags: Fragment;"]
[56898,"'BDH2'",198,208,203,"01100///Metabolic pathways+++00650///Butanoate metabolism+++00072///Synthesis and degradation of ketone bodies",null,"M00088///Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone","R01361///(R)-3-Hydroxybutanoate:NAD+ oxidoreductase   (R)-3-Hydroxybutanoate + NAD+ <=> Acetoacetate + NADH + H+","GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005739///mitochondrion","GO:0051287///NAD binding+++GO:0008667///2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity+++GO:0016628///oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor+++GO:0016491///oxidoreductase activity+++GO:0003858///3-hydroxybutyrate dehydrogenase activity","GO:0006635///fatty acid beta-oxidation+++GO:0042168///heme metabolic process+++GO:0019290///siderophore biosynthetic process+++GO:0046951///ketone body biosynthetic process+++GO:0055072///iron ion homeostasis+++GO:0030855///epithelial cell differentiation+++GO:0055114///oxidation-reduction process","IPR036291///NAD(P)-binding domain superfamily+++IPR020904///Short-chain dehydrogenase/reductase, conserved site+++IPR002347///Short-chain dehydrogenase/reductase SDR","[BDH2_HUMAN|Reviewed]RecName: Full=3-hydroxybutyrate dehydrogenase type 2; EC=1.1.1.-; EC=1.1.1.30; AltName: Full=Dehydrogenase/reductase SDR family member 6; AltName: Full=Oxidoreductase UCPA; AltName: Full=R-beta-hydroxybutyrate dehydrogenase; AltName: Full=Short chain dehydrogenase/reductase family 15C member 1;+++[A0A024RDG9_HUMAN|Unreviewed]SubName: Full=3-hydroxybutyrate dehydrogenase, type 2, isoform CRA_b {ECO:0000313|EMBL:EAX06167.1};+++[A0A024RDJ8_HUMAN|Unreviewed]SubName: Full=3-hydroxybutyrate dehydrogenase, type 2, isoform CRA_a {ECO:0000313|EMBL:EAX06166.1};+++[D6R9U8_HUMAN|Unreviewed]SubName: Full=3-hydroxybutyrate dehydrogenase type 2 {ECO:0000313|Ensembl:ENSP00000422891}; Flags: Fragment;+++[D6RBF6_HUMAN|Unreviewed]SubName: Full=3-hydroxybutyrate dehydrogenase type 2 {ECO:0000313|Ensembl:ENSP00000424173};+++[D6RFG2_HUMAN|Unreviewed]SubName: Full=3-hydroxybutyrate dehydrogenase type 2 {ECO:0000313|Ensembl:ENSP00000421516};+++[D6RIR6_HUMAN|Unreviewed]SubName: Full=3-hydroxybutyrate dehydrogenase type 2 {ECO:0000313|Ensembl:ENSP00000427442}; Flags: Fragment;+++[L0R823_HUMAN|Unreviewed]SubName: Full=Alternative protein BDH2 {ECO:0000313|EMBL:CCO13686.1};"]
[56913,"'C1GALT1'",448,559,503.5,"00512///Mucin type O-glycan biosynthesis+++01100///Metabolic pathways",null,"M00056///O-glycan biosynthesis, mucin type core","R05908///UDP-D-galactose + Tn antigen <=> UDP + T antigen","GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0016263///glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity+++GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0007275///multicellular organism development+++GO:0001822///kidney development+++GO:0006486///protein glycosylation+++GO:0060576///intestinal epithelial cell development+++GO:0016267///O-glycan processing, core 1+++GO:0016266///O-glycan processing+++GO:0006493///protein O-linked glycosylation+++GO:0001525///angiogenesis+++GO:0030154///cell differentiation","IPR026842///Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1+++IPR003378///Fringe-like","[C1GLT_HUMAN|Reviewed]RecName: Full=Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; EC=2.4.1.122 {ECO:0000269|PubMed:11677243}; AltName: Full=B3Gal-T8; AltName: Full=Core 1 O-glycan T-synthase; AltName: Full=Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; Short=Beta-1,3-galactosyltransferase; AltName: Full=Core 1 beta1,3-galactosyltransferase 1; Short=C1GalT1; Short=Core 1 beta3-Gal-T1;+++[A0A024RA32_HUMAN|Unreviewed]SubName: Full=Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, isoform CRA_a {ECO:0000313|EMBL:EAW93590.1};+++[C9JDX1_HUMAN|Unreviewed]SubName: Full=Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000415400}; Flags: Fragment;+++[C9K0C8_HUMAN|Unreviewed]SubName: Full=Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 {ECO:0000313|Ensembl:ENSP00000407666}; Flags: Fragment;"]
[56935,"'SMCO4'",33,23,28,"03060///Protein export",{"$nulls":3},"GO:0005575///cellular_component+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0008150///biological_process","IPR027960///Protein of unknown function DUF4519","[SMCO4_HUMAN|Reviewed]RecName: Full=Single-pass membrane and coiled-coil domain-containing protein 4; AltName: Full=Protein FN5;+++[A0A024R3A3_HUMAN|Unreviewed]SubName: Full=FN5 protein, isoform CRA_a {ECO:0000313|EMBL:EAW66905.1};+++[E9PQ76_HUMAN|Unreviewed]SubName: Full=Single-pass membrane and coiled-coil domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000432581}; Flags: Fragment;+++[E9PSB8_HUMAN|Unreviewed]SubName: Full=Single-pass membrane and coiled-coil domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000435827}; Flags: Fragment;"]
[56950,"'SMYD2'",250,261,255.5,null,"H01017///Choanal atresia and lymphedema",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding+++GO:0016278///lysine N-methyltransferase activity+++GO:0016740///transferase activity+++GO:0002039///p53 binding+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0008168///methyltransferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046975///histone methyltransferase activity (H3-K36 specific)","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0032259///methylation+++GO:0043516///regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0016571///histone methylation+++GO:0007507///heart development+++GO:0008285///negative regulation of cell proliferation+++GO:0006325///chromatin organization+++GO:0034968///histone lysine methylation+++GO:0018027///peptidyl-lysine dimethylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0010452///histone H3-K36 methylation","IPR001214///SET domain+++IPR002893///Zinc finger, MYND-type+++IPR011990///Tetratricopeptide-like helical domain superfamily","[SMYD2_HUMAN|Reviewed]RecName: Full=N-lysine methyltransferase SMYD2; EC=2.1.1.-; AltName: Full=HSKM-B; AltName: Full=Histone methyltransferase SMYD2; EC=2.1.1.43; AltName: Full=Lysine N-methyltransferase 3C; AltName: Full=SET and MYND domain-containing protein 2;+++[B0R0U3_HUMAN|Unreviewed]SubName: Full=N-lysine methyltransferase SMYD2 {ECO:0000313|Ensembl:ENSP00000409822}; Flags: Fragment;+++[I6L9D1_HUMAN|Unreviewed]SubName: Full=SMYD2 protein {ECO:0000313|EMBL:AAH49367.2};+++[Q05C86_HUMAN|Unreviewed]SubName: Full=SMYD2 protein {ECO:0000313|EMBL:AAH28104.1}; Flags: Fragment;"]
[56978,"'PRDM8'",55,42,48.5,null,"H00810///Progressive myoclonic epilepsy (PME/ EPM)",null,null,"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0016740///transferase activity+++GO:0008168///methyltransferase activity","GO:0014003///oligodendrocyte development+++GO:0032259///methylation+++GO:0007399///nervous system development+++GO:0006357///regulation of transcription by RNA polymerase II","IPR001214///SET domain+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[PRDM8_HUMAN|Reviewed]RecName: Full=PR domain zinc finger protein 8; EC=2.1.1.-; AltName: Full=PR domain-containing protein 8;+++[A0A024RDC4_HUMAN|Unreviewed]SubName: Full=PR domain containing 8, isoform CRA_a {ECO:0000313|EMBL:EAX05852.1};+++[E9PEH0_HUMAN|Unreviewed]SubName: Full=PR domain zinc finger protein 8 {ECO:0000313|Ensembl:ENSP00000425149}; Flags: Fragment;+++[Q05CA1_HUMAN|Unreviewed]SubName: Full=PRDM8 protein {ECO:0000313|EMBL:AAH27929.1}; Flags: Fragment;"]
[56996,"'SLC12A9'",437,431,434,"04621///NOD-like receptor signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome","GO:0015379///potassium:chloride symporter activity+++GO:0015377///cation:chloride symporter activity+++GO:0005215///transporter activity","GO:0006884///cell volume homeostasis+++GO:1990573///potassium ion import across plasma membrane+++GO:0055085///transmembrane transport+++GO:0006811///ion transport+++GO:0055064///chloride ion homeostasis+++GO:0055075///potassium ion homeostasis+++GO:1902476///chloride transmembrane transport","IPR004841///Amino acid permease/ SLC12A domain+++IPR018491///SLC12A transporter, C-terminal+++IPR030345///Solute carrier family 12 member 9","[S12A9_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 9; AltName: Full=Cation-chloride cotransporter 6; Short=hCCC6; AltName: Full=Cation-chloride cotransporter-interacting protein 1; Short=CCC-interacting protein 1; Short=hCIP1; AltName: Full=Potassium-chloride transporter 9; AltName: Full=WO3.3;+++[C9J0I5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 9 {ECO:0000313|Ensembl:ENSP00000406560}; Flags: Fragment;+++[C9JBD8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 9 {ECO:0000313|Ensembl:ENSP00000410692}; Flags: Fragment;+++[C9JMQ7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 9 {ECO:0000313|Ensembl:ENSP00000408571}; Flags: Fragment;+++[D6W5X3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 9, isoform CRA_d {ECO:0000313|EMBL:EAW76482.1};+++[D6W5X5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 9, isoform CRA_c {ECO:0000313|EMBL:EAW76478.1};+++[F8WEK3_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 9 {ECO:0000313|Ensembl:ENSP00000401583};+++[Q9H7I6_HUMAN|Unreviewed]SubName: Full=FLJ00100 protein {ECO:0000313|EMBL:BAB15784.1}; Flags: Fragment;"]
[57019,"'CIAPIN1'",550,436,493,null,"H00999///Coenzyme Q10 deficiency",null,null,"GO:0005758///mitochondrial intermembrane space+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005739///mitochondrion+++GO:0005730///nucleolus","GO:0009055///electron transfer activity+++GO:0046872///metal ion binding+++GO:0051536///iron-sulfur cluster binding+++GO:0051539///4 iron, 4 sulfur cluster binding+++GO:0051537///2 iron, 2 sulfur cluster binding+++GO:0008168///methyltransferase activity+++GO:0005515///protein binding","GO:0016226///iron-sulfur cluster assembly+++GO:0022900///electron transport chain+++GO:0043066///negative regulation of apoptotic process+++GO:0030097///hemopoiesis+++GO:0006915///apoptotic process+++GO:0032259///methylation","IPR007785///Anamorsin+++IPR013216///Methyltransferase type 11+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[CPIN1_HUMAN|Reviewed]RecName: Full=Anamorsin {ECO:0000255|HAMAP-Rule:MF_03115}; AltName: Full=Cytokine-induced apoptosis inhibitor 1 {ECO:0000255|HAMAP-Rule:MF_03115}; AltName: Full=Fe-S cluster assembly protein DRE2 homolog {ECO:0000255|HAMAP-Rule:MF_03115};+++[H3BPG7_HUMAN|Unreviewed]SubName: Full=Anamorsin {ECO:0000313|Ensembl:ENSP00000455309};+++[H3BQ23_HUMAN|Unreviewed]SubName: Full=Anamorsin {ECO:0000313|Ensembl:ENSP00000455572}; Flags: Fragment;+++[H3BT65_HUMAN|Unreviewed]SubName: Full=Anamorsin {ECO:0000313|Ensembl:ENSP00000457042};+++[H3BTT4_HUMAN|Unreviewed]SubName: Full=Anamorsin {ECO:0000313|Ensembl:ENSP00000457318}; Flags: Fragment;+++[H3BTZ8_HUMAN|Unreviewed]SubName: Full=Anamorsin {ECO:0000313|Ensembl:ENSP00000457400}; Flags: Fragment;+++[H3BUG4_HUMAN|Unreviewed]SubName: Full=Anamorsin {ECO:0000313|Ensembl:ENSP00000457622};+++[H3BV90_HUMAN|Unreviewed]RecName: Full=Fe-S cluster assembly protein DRE2 {ECO:0000256|SAAS:SAAS00375231};"]
[5706,"'PSMC6'",289,372,330.5,"05169///Epstein-Barr virus infection+++03050///Proteasome",null,"M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0000502///proteasome complex+++GO:0031597///cytosolic proteasome complex+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0022624///proteasome accessory complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016234///inclusion body","GO:0042802///identical protein binding+++GO:0036402///proteasome-activating ATPase activity+++GO:0030674///protein binding, bridging+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0016887///ATPase activity+++GO:0016787///hydrolase activity","GO:0030163///protein catabolic process+++GO:0030433///ubiquitin-dependent ERAD pathway+++GO:0045899///positive regulation of RNA polymerase II transcriptional preinitiation complex assembly+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0090261///positive regulation of inclusion body assembly","IPR003960///ATPase, AAA-type, conserved site+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003959///ATPase, AAA-type, core+++IPR005937///26S proteasome regulatory subunit P45-like+++IPR003593///AAA+ ATPase domain+++IPR035263///26S proteasome regulatory subunit 10B","[PRS10_HUMAN|Reviewed]RecName: Full=26S proteasome regulatory subunit 10B; AltName: Full=26S proteasome AAA-ATPase subunit RPT4; AltName: Full=Proteasome 26S subunit ATPase 6; AltName: Full=Proteasome subunit p42;+++[A0A087X2I1_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000484998};+++[H0YJC0_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000451156}; Flags: Fragment;+++[H0YJD2_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000451241}; Flags: Fragment;+++[H0YJE9_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000451340};+++[H0YJS8_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000452048}; Flags: Fragment;+++[H0YJT1_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000452072};+++[H0YJW2_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000452253}; Flags: Fragment;+++[H0YJX2_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000452388}; Flags: Fragment;+++[H0YJY8_HUMAN|Unreviewed]SubName: Full=26S proteasome regulatory subunit 10B {ECO:0000313|Ensembl:ENSP00000452511};+++[V9HW24_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 73 {ECO:0000313|EMBL:ACI45991.1};"]
[57099,"'AVEN'",271,206,238.5,"04137///Mitophagy - animal+++04713///Circadian entrainment+++05010///Alzheimer's disease+++04140///Autophagy - animal+++04921///Oxytocin signaling pathway+++04080///Neuroactive ligand-receptor interaction+++04725///Cholinergic synapse+++04020///Calcium signaling pathway+++04970///Salivary secretion+++04371///Apelin signaling pathway+++04810///Regulation of actin cytoskeleton",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0005622///intracellular+++GO:0016020///membrane","GO:0005515///protein binding","GO:0043066///negative regulation of apoptotic process+++GO:0006915///apoptotic process","IPR026187///Cell death regulator Aven","[AVEN_HUMAN|Reviewed]RecName: Full=Cell death regulator Aven;+++[H0YKR0_HUMAN|Unreviewed]SubName: Full=Cell death regulator Aven {ECO:0000313|Ensembl:ENSP00000452906}; Flags: Fragment;"]
[57120,"'GOPC'",608,779,693.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0014069///postsynaptic density+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0030425///dendrite+++GO:0005737///cytoplasm+++GO:0030140///trans-Golgi network transport vesicle+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0030660///Golgi-associated vesicle membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0044325///ion channel binding","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006893///Golgi to plasma membrane transport+++GO:0043004///cytoplasmic sequestering of CFTR protein+++GO:0045176///apical protein localization+++GO:0015031///protein transport+++GO:0010360///negative regulation of anion channel activity+++GO:0051260///protein homooligomerization+++GO:2000009///negative regulation of protein localization to cell surface","IPR038879///Golgi-associated PDZ and coiled-coil motif-containing protein+++IPR001478///PDZ domain+++IPR036034///PDZ superfamily","[GOPC_HUMAN|Reviewed]RecName: Full=Golgi-associated PDZ and coiled-coil motif-containing protein; AltName: Full=CFTR-associated ligand; AltName: Full=Fused in glioblastoma; AltName: Full=PDZ protein interacting specifically with TC10; Short=PIST;+++[F5H1Y4_HUMAN|Unreviewed]SubName: Full=Golgi-associated PDZ and coiled-coil motif containing protein transcript variant 3 {ECO:0000313|EMBL:AGU13714.1}; SubName: Full=Golgi-associated PDZ and coiled-coil motif-containing protein {ECO:0000313|Ensembl:ENSP00000445690};+++[T1WFC1_HUMAN|Unreviewed]SubName: Full=Golgi-associated PDZ and coiled-coil motif containing protein transcript variant 4 {ECO:0000313|EMBL:AGU13713.1};"]
[57142,"'RTN4'",20083,20677,20380,"05010///Alzheimer's disease",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0005622///intracellular+++GO:0042995///cell projection+++GO:0098826///endoplasmic reticulum tubular network membrane+++GO:0005783///endoplasmic reticulum+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0071782///endoplasmic reticulum tubular network+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0014069///postsynaptic density+++GO:0005635///nuclear envelope","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0045296///cadherin binding","GO:0030308///negative regulation of cell growth+++GO:0042981///regulation of apoptotic process+++GO:0071786///endoplasmic reticulum tubular network organization+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0051960///regulation of nervous system development+++GO:1990809///endoplasmic reticulum tubular network membrane organization+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0007399///nervous system development+++GO:0007413///axonal fasciculation+++GO:1905580///positive regulation of ERBB3 signaling pathway+++GO:2000172///regulation of branching morphogenesis of a nerve+++GO:0001825///blastocyst formation+++GO:0050771///negative regulation of axonogenesis+++GO:0050821///protein stabilization+++GO:0030517///negative regulation of axon extension+++GO:0021801///cerebral cortex radial glia guided migration+++GO:1905552///positive regulation of protein localization to endoplasmic reticulum+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0010634///positive regulation of epithelial cell migration+++GO:0051292///nuclear pore complex assembly+++GO:0006915///apoptotic process+++GO:0030334///regulation of cell migration+++GO:0071787///endoplasmic reticulum tubular network formation","IPR003388///Reticulon","[RTN4_HUMAN|Reviewed]RecName: Full=Reticulon-4; AltName: Full=Foocen; AltName: Full=Neurite outgrowth inhibitor; Short=Nogo protein; AltName: Full=Neuroendocrine-specific protein; Short=NSP; AltName: Full=Neuroendocrine-specific protein C homolog; AltName: Full=RTN-x; AltName: Full=Reticulon-5;+++[A0A0U1RQR6_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[C9J685_HUMAN|Unreviewed]SubName: Full=Reticulon-4 {ECO:0000313|Ensembl:ENSP00000411628}; Flags: Fragment;+++[D6W5C2_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[F8W914_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};+++[H7C106_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[Q3LIF1_HUMAN|Unreviewed]SubName: Full=NOGO-A {ECO:0000313|EMBL:BAE45717.1}; Flags: Fragment;+++[Q3LIF4_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[Q53R94_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RTN4 {ECO:0000313|EMBL:AAY24029.1}; Flags: Fragment;+++[Q53RF4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein RTN4 {ECO:0000313|EMBL:AAX93116.1}; Flags: Fragment;+++[Q53SY1_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713}; Flags: Fragment;+++[Q6IPN0_HUMAN|Unreviewed]RecName: Full=Reticulon {ECO:0000256|RuleBase:RU210713};"]
[5716,"'PSMD10'",393,402,397.5,"04140///Autophagy - animal+++04136///Autophagy - other+++04138///Autophagy - yeast",{"$nulls":3},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0008540///proteasome regulatory particle, base subcomplex+++GO:0045111///intermediate filament cytoskeleton+++GO:0005737///cytoplasm+++GO:0005838///proteasome regulatory particle+++GO:0000502///proteasome complex","GO:0008134///transcription factor binding+++GO:0005515///protein binding","GO:0043409///negative regulation of MAPK cascade+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0070682///proteasome regulatory particle assembly+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0030307///positive regulation of cell growth+++GO:0006915///apoptotic process+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0043066///negative regulation of apoptotic process+++GO:0043687///post-translational protein modification+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0031398///positive regulation of protein ubiquitination","IPR020683///Ankyrin repeat-containing domain+++IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR039334///26S proteasome non-ATPase regulatory subunit 10-like","[PSD10_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 10; AltName: Full=26S proteasome regulatory subunit p28; AltName: Full=Gankyrin; AltName: Full=p28(GANK);+++[B1AJY5_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 10 {ECO:0000313|Ensembl:ENSP00000361369};+++[B1AJY6_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 10 {ECO:0000313|Ensembl:ENSP00000361370};+++[B1AJY7_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 10 {ECO:0000313|Ensembl:ENSP00000345963};"]
[57181,"'SLC39A10'",293,425,359,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane","GO:0046873///metal ion transmembrane transporter activity+++GO:0005385///zinc ion transmembrane transporter activity","GO:0002903///negative regulation of B cell apoptotic process+++GO:0071578///zinc ion import across plasma membrane+++GO:0006882///cellular zinc ion homeostasis+++GO:1903615///positive regulation of protein tyrosine phosphatase activity+++GO:0006811///ion transport+++GO:0030001///metal ion transport+++GO:0050861///positive regulation of B cell receptor signaling pathway+++GO:0006829///zinc ion transport+++GO:0055085///transmembrane transport+++GO:0030890///positive regulation of B cell proliferation","IPR003689///Zinc/iron permease","[S39AA_HUMAN|Reviewed]RecName: Full=Zinc transporter ZIP10; AltName: Full=Solute carrier family 39 member 10; AltName: Full=Zrt- and Irt-like protein 10; Short=ZIP-10; Flags: Precursor;+++[A0A024R3W5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 39 (Zinc transporter), member 10, isoform CRA_a {ECO:0000313|EMBL:EAW70118.1};+++[C9J0F5_HUMAN|Unreviewed]SubName: Full=Zinc transporter ZIP10 {ECO:0000313|Ensembl:ENSP00000406590}; Flags: Fragment;+++[E7ENT5_HUMAN|Unreviewed]SubName: Full=Zinc transporter ZIP10 {ECO:0000313|Ensembl:ENSP00000389640}; Flags: Fragment;+++[E7EV45_HUMAN|Unreviewed]SubName: Full=Zinc transporter ZIP10 {ECO:0000313|Ensembl:ENSP00000409272}; Flags: Fragment;+++[F2Z341_HUMAN|Unreviewed]SubName: Full=Zinc transporter ZIP10 {ECO:0000313|Ensembl:ENSP00000394995};+++[Q05C42_HUMAN|Unreviewed]SubName: Full=SLC39A10 protein {ECO:0000313|EMBL:AAH29413.1}; Flags: Fragment;"]
[5720,"'PSME1'",632,410,521,"03050///Proteasome+++04612///Antigen processing and presentation",null,"M00337///Immunoproteasome",null,"GO:0005829///cytosol+++GO:0000502///proteasome complex+++GO:0005737///cytoplasm+++GO:0008537///proteasome activator complex+++GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0061133///endopeptidase activator activity","GO:0010950///positive regulation of endopeptidase activity+++GO:0016579///protein deubiquitination+++GO:0019884///antigen processing and presentation of exogenous antigen+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0043687///post-translational protein modification+++GO:0061136///regulation of proteasomal protein catabolic process","IPR036252///Proteasome activator superfamily+++IPR036996///Proteasome activator PA28, N-terminal domain superfamily+++IPR003185///Proteasome activator PA28, N-terminal domain+++IPR003186///Proteasome activator PA28, C-terminal domain+++IPR009077///Proteasome activator PA28+++IPR036997///Proteasome activator PA28, C-terminal domain superfamily","[PSME1_HUMAN|Reviewed]RecName: Full=Proteasome activator complex subunit 1; AltName: Full=11S regulator complex subunit alpha; Short=REG-alpha; AltName: Full=Activator of multicatalytic protease subunit 1; AltName: Full=Interferon gamma up-regulated I-5111 protein; Short=IGUP I-5111; AltName: Full=Proteasome activator 28 subunit alpha; Short=PA28a; Short=PA28alpha;+++[A0A0K0K1L8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory sperm binding protein Li 129m {ECO:0000313|EMBL:ACV87212.1};+++[H0YKK6_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 1 {ECO:0000313|Ensembl:ENSP00000452843};+++[H0YLU2_HUMAN|Unreviewed]SubName: Full=Proteasome activator complex subunit 1 {ECO:0000313|Ensembl:ENSP00000453340}; Flags: Fragment;+++[Q6FHU3_HUMAN|Unreviewed]SubName: Full=PSME1 protein {ECO:0000313|EMBL:CAG46459.1}; Flags: Fragment;+++[Q86SZ9_HUMAN|Unreviewed]SubName: Full=Full-length cDNA clone CS0DJ006YA22 of T cells (Jurkat cell line) of Homo sapiens (human) {ECO:0000313|EMBL:CAD62621.1}; Flags: Fragment;"]
[57226,"'LYRM2'",289,282,285.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"IPR008011///Complex 1 LYR protein+++IPR026868///LYR motif-containing protein 2","[LYRM2_HUMAN|Reviewed]RecName: Full=LYR motif-containing protein 2;+++[E5RG38_HUMAN|Unreviewed]SubName: Full=LYR motif-containing protein 2 {ECO:0000313|Ensembl:ENSP00000427859};+++[E5RJK7_HUMAN|Unreviewed]SubName: Full=LYR motif-containing protein 2 {ECO:0000313|Ensembl:ENSP00000428207};+++[G3V136_HUMAN|Unreviewed]SubName: Full=LYR motif-containing protein 2 {ECO:0000313|Ensembl:ENSP00000430316};"]
[57332,"'CBX8'",57,51,54,{"$nulls":4},"GO:0031519///PcG protein complex+++GO:0035102///PRC1 complex+++GO:0005654///nucleoplasm+++GO:0000792///heterochromatin+++GO:0005634///nucleus+++GO:0000151///ubiquitin ligase complex+++GO:0000790///nuclear chromatin","GO:0035064///methylated histone binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:0005515///protein binding+++GO:0003727///single-stranded RNA binding","GO:0006325///chromatin organization+++GO:0008284///positive regulation of cell proliferation+++GO:0032967///positive regulation of collagen biosynthetic process+++GO:0050790///regulation of catalytic activity+++GO:0016574///histone ubiquitination+++GO:0070301///cellular response to hydrogen peroxide+++GO:0045739///positive regulation of DNA repair+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR000953///Chromo/chromo shadow domain+++IPR023779///Chromo domain, conserved site+++IPR016197///Chromo-like domain superfamily+++IPR023780///Chromo domain+++IPR033773///CBX family C-terminal motif","[CBX8_HUMAN|Reviewed]RecName: Full=Chromobox protein homolog 8; AltName: Full=Polycomb 3 homolog; Short=Pc3; Short=hPc3; AltName: Full=Rectachrome 1;+++[C9J6K3_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 8 {ECO:0000313|Ensembl:ENSP00000405058}; Flags: Fragment;+++[C9JM54_HUMAN|Unreviewed]SubName: Full=Chromobox protein homolog 8 {ECO:0000313|Ensembl:ENSP00000408753}; Flags: Fragment;+++[Q9P2Z1_HUMAN|Unreviewed]SubName: Full=NADH dehydrogenase subunit 3 homolog/ND3 homolog {ECO:0000313|EMBL:AAB36221.1}; Flags: Fragment;"]
[5739,"'PTGIR'",1,2,1.5,"04270///Vascular smooth muscle contraction+++04080///Neuroactive ligand-receptor interaction+++04611///Platelet activation",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol","GO:0004930///G protein-coupled receptor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007267///cell-cell signaling+++GO:0007187///G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0032496///response to lipopolysaccharide+++GO:0006954///inflammatory response+++GO:0010642///negative regulation of platelet-derived growth factor receptor signaling pathway+++GO:0007204///positive regulation of cytosolic calcium ion concentration","IPR017452///GPCR, rhodopsin-like, 7TM+++IPR000370///Prostacyclin (prostanoid IP) receptor+++IPR008365///Prostanoid receptor+++IPR000276///G protein-coupled receptor, rhodopsin-like","[PI2R_HUMAN|Reviewed]RecName: Full=Prostacyclin receptor; AltName: Full=Prostaglandin I2 receptor; Short=PGI receptor; Short=PGI2 receptor; AltName: Full=Prostanoid IP receptor; Flags: Precursor;+++[A0A0B4J2A7_HUMAN|Unreviewed]SubName: Full=Prostacyclin receptor {ECO:0000313|Ensembl:ENSP00000468970}; SubName: Full=Prostaglandin I2 (Prostacyclin) receptor (IP), isoform CRA_b {ECO:0000313|EMBL:EAW57433.1};+++[M0QXV5_HUMAN|Unreviewed]SubName: Full=Prostacyclin receptor {ECO:0000313|Ensembl:ENSP00000469408};+++[M0QZI2_HUMAN|Unreviewed]SubName: Full=Prostacyclin receptor {ECO:0000313|Ensembl:ENSP00000470566};+++[M0QZW0_HUMAN|Unreviewed]SubName: Full=Prostacyclin receptor {ECO:0000313|Ensembl:ENSP00000470799};+++[Q2YD89_HUMAN|Unreviewed]SubName: Full=Prostaglandin I2 (Prostacyclin) receptor (IP) {ECO:0000313|EMBL:AAI10343.1};"]
[57419,"'SLC24A3'",10,19,14.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005262///calcium channel activity+++GO:0015293///symporter activity+++GO:0015297///antiporter activity+++GO:0008273///calcium, potassium:sodium antiporter activity","GO:0006874///cellular calcium ion homeostasis+++GO:0070588///calcium ion transmembrane transport+++GO:0006811///ion transport+++GO:0006814///sodium ion transport+++GO:0006813///potassium ion transport+++GO:0006816///calcium ion transport+++GO:0055085///transmembrane transport+++GO:0035725///sodium ion transmembrane transport","IPR004837///Sodium/calcium exchanger membrane region+++IPR004481///Sodium/potassium/calcium exchanger+++IPR030248///Sodium/potassium/calcium exchanger 3","[NCKX3_HUMAN|Reviewed]RecName: Full=Sodium/potassium/calcium exchanger 3; AltName: Full=Na(+)/K(+)/Ca(2+)-exchange protein 3; AltName: Full=Solute carrier family 24 member 3; Flags: Precursor;"]
[57460,"'PPM1H'",139,231,185,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse","GO:0016787///hydrolase activity+++GO:0003824///catalytic activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity","GO:0006470///protein dephosphorylation","IPR015655///Protein phosphatase 2C family+++IPR036457///PPM-type phosphatase domain superfamily+++IPR001932///PPM-type phosphatase domain","[PPM1H_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1H; EC=3.1.3.16;+++[S5ZYJ2_HUMAN|Unreviewed]SubName: Full=SRGAP1/PPM1H fusion protein {ECO:0000313|EMBL:AGT29351.1};"]
[57475,"'PLEKHH1'",106.07,159,132.535,"04140///Autophagy - animal+++01100///Metabolic pathways+++04137///Mitophagy - animal+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis",null,null,"R05916///UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143","GO:0005856///cytoskeleton",null,null,"IPR019749///Band 4.1 domain+++IPR035963///FERM superfamily, second domain+++IPR019748///FERM central domain+++IPR011993///PH-like domain superfamily+++IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR038185///MyTH4 domain superfamily+++IPR000299///FERM domain+++IPR000857///MyTH4 domain+++IPR001849///Pleckstrin homology domain","[PKHH1_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family H member 1; Short=PH domain-containing family H member 1;+++[H0YKY5_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family H member 1 {ECO:0000313|Ensembl:ENSP00000452988}; Flags: Fragment;+++[H0YLU5_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family H member 1 {ECO:0000313|Ensembl:ENSP00000453343}; Flags: Fragment;+++[H0YMQ6_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family H member 1 {ECO:0000313|Ensembl:ENSP00000453699}; Flags: Fragment;"]
[57496,"'MRTFB'",237,423,330,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0004864///protein phosphatase inhibitor activity+++GO:0045296///cadherin binding+++GO:0003779///actin binding+++GO:0003713///transcription coactivator activity","GO:0051145///smooth muscle cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0045844///positive regulation of striated muscle tissue development","IPR036361///SAP domain superfamily+++IPR003034///SAP domain+++IPR004018///RPEL repeat","[MRTFB_HUMAN|Reviewed]RecName: Full=Myocardin-related transcription factor B {ECO:0000305}; Short=MRTF-B {ECO:0000305}; AltName: Full=MKL/myocardin-like protein 2; AltName: Full=Megakaryoblastic leukemia 2 {ECO:0000303|PubMed:14565952};+++[A1L1A9_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[I3L0U1_HUMAN|Unreviewed]SubName: Full=Myocardin-related transcription factor B {ECO:0000313|Ensembl:ENSP00000458340}; Flags: Fragment;+++[I3L2A0_HUMAN|Unreviewed]SubName: Full=Myocardin-related transcription factor B {ECO:0000313|Ensembl:ENSP00000459518}; Flags: Fragment;+++[I3L2S3_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};+++[I3L3Z7_HUMAN|Unreviewed]SubName: Full=Myocardin-related transcription factor B {ECO:0000313|Ensembl:ENSP00000460848}; Flags: Fragment;+++[Q05BP1_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;"]
[57513,"'CASKIN2'",827,817,822,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process","IPR035498///Caskin1/2, SAM repeat 2+++IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR001452///SH3 domain+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR035497///Caskin1/2, SAM repeat 1+++IPR032117///Caskin, C-terminal+++IPR035499///Caskin2, SH3 domain+++IPR020683///Ankyrin repeat-containing domain+++IPR036028///SH3-like domain superfamily+++IPR002110///Ankyrin repeat+++IPR001660///Sterile alpha motif domain","[CSKI2_HUMAN|Reviewed]RecName: Full=Caskin-2; AltName: Full=CASK-interacting protein 2;+++[J3QKS3_HUMAN|Unreviewed]SubName: Full=Caskin-2 {ECO:0000313|Ensembl:ENSP00000463211}; Flags: Fragment;+++[J3QRN1_HUMAN|Unreviewed]SubName: Full=Caskin-2 {ECO:0000313|Ensembl:ENSP00000464300};"]
[57532,"'NUFIP2'",650,961,805.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0042788///polysomal ribosome+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0010494///cytoplasmic stress granule","GO:0005515///protein binding+++GO:0003723///RNA binding",null,"IPR032747///Nuclear fragile X mental retardation-interacting protein 2","[NUFP2_HUMAN|Reviewed]RecName: Full=Nuclear fragile X mental retardation-interacting protein 2; AltName: Full=82 kDa FMRP-interacting protein; Short=82-FIP; AltName: Full=Cell proliferation-inducing gene 1 protein; AltName: Full=FMRP-interacting protein 2;"]
[57544,"'TXNDC16'",15,23,19,"04120///Ubiquitin mediated proteolysis+++04144///Endocytosis+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04668///TNF signaling pathway","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H01232///Syndromic multisystem autoimmune disease",null,null,"GO:0005788///endoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005623///cell+++GO:0005783///endoplasmic reticulum+++GO:0070062///extracellular exosome","GO:0005515///protein binding","GO:0008150///biological_process+++GO:0045454///cell redox homeostasis","IPR013766///Thioredoxin domain+++IPR036249///Thioredoxin-like superfamily","[TXD16_HUMAN|Reviewed]RecName: Full=Thioredoxin domain-containing protein 16 {ECO:0000312|HGNC:HGNC:19965}; Flags: Precursor;+++[B7ZME4_HUMAN|Unreviewed]SubName: Full=TXNDC16 protein {ECO:0000313|EMBL:AAI44470.1};+++[G3V2S5_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000450839}; Flags: Fragment;+++[H0YJI6_HUMAN|Unreviewed]SubName: Full=Thioredoxin domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000451619}; Flags: Fragment;"]
[57565,"'KLHL14'",0,1,0.5,{"$nulls":4},"GO:0043005///neuron projection+++GO:0015629///actin cytoskeleton+++GO:0005829///cytosol+++GO:0016235///aggresome+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0016020///membrane",null,"GO:0016567///protein ubiquitination","IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR017096///BTB-kelch protein+++IPR030584///Kelch-like protein 14+++IPR015915///Kelch-type beta propeller+++IPR006652///Kelch repeat type 1+++IPR011705///BTB/Kelch-associated","[KLH14_HUMAN|Reviewed]RecName: Full=Kelch-like protein 14; AltName: Full=Protein interactor of Torsin-1A; Short=Printor; Short=Protein interactor of torsinA;+++[J3QQM3_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 14 {ECO:0000313|Ensembl:ENSP00000463803}; Flags: Fragment;"]
[57583,"'TMEM181'",363,426,394.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015643///toxic substance binding","GO:0009405///pathogenesis","IPR013544///Domain of unknown function DUF1725+++IPR036691///Endonuclease/exonuclease/phosphatase superfamily+++IPR000477///Reverse transcriptase domain+++IPR005135///Endonuclease/exonuclease/phosphatase","[TM181_HUMAN|Reviewed]RecName: Full=Transmembrane protein 181;+++[Q8N4V6_HUMAN|Unreviewed]SubName: Full=TMEM181 protein {ECO:0000313|EMBL:AAH33450.1}; Flags: Fragment;"]
[576,"'ADGRB2'",1170,1348,1259,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005813///centrosome+++GO:0016021///integral component of membrane","GO:0004930///G protein-coupled receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding","GO:0051965///positive regulation of synapse assembly+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0033173///calcineurin-NFAT signaling cascade+++GO:0016525///negative regulation of angiogenesis+++GO:0007422///peripheral nervous system development+++GO:0007166///cell surface receptor signaling pathway+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction","IPR036445///GPCR family 2, extracellular hormone receptor domain superfamily+++IPR000884///Thrombospondin type-1 (TSP1) repeat+++IPR000832///GPCR, family 2, secretin-like+++IPR017981///GPCR, family 2-like+++IPR032471///GAIN domain, N-terminal+++IPR008077///GPCR, family 2, brain-specific angiogenesis inhibitor+++IPR000203///GPS motif+++IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR001879///GPCR, family 2, extracellular hormone receptor domain","[AGRB2_HUMAN|Reviewed]RecName: Full=Adhesion G protein-coupled receptor B2 {ECO:0000303|PubMed:25713288}; AltName: Full=Brain-specific angiogenesis inhibitor 2; Flags: Precursor;+++[A2A3C1_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor B2 {ECO:0000313|Ensembl:ENSP00000381550};+++[A2A3C2_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor B2 {ECO:0000313|Ensembl:ENSP00000381548};+++[A2A3C3_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor B2 {ECO:0000313|Ensembl:ENSP00000381555};+++[A2A3C4_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor B2 {ECO:0000313|Ensembl:ENSP00000410921}; Flags: Fragment;+++[A2A3C6_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor B2 {ECO:0000313|Ensembl:ENSP00000381564};+++[E9PND1_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor B2 {ECO:0000313|Ensembl:ENSP00000437219}; Flags: Fragment;"]
[57619,"'SHROOM3'",3256,4527,3891.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01916///Stocco dos Santos X-linked mental retardation syndrome",null,null,"GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0030864///cortical actin cytoskeleton+++GO:0043296///apical junction complex+++GO:0016324///apical plasma membrane+++GO:0005874///microtubule+++GO:0005912///adherens junction+++GO:0005737///cytoplasm","GO:0003779///actin binding+++GO:0051015///actin filament binding","GO:0007275///multicellular organism development+++GO:0008360///regulation of cell shape+++GO:0045176///apical protein localization+++GO:0001843///neural tube closure+++GO:0002064///epithelial cell development+++GO:0007389///pattern specification process+++GO:0000902///cell morphogenesis+++GO:0043482///cellular pigment accumulation+++GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization","IPR014799///Apx/Shrm Domain 2+++IPR027685///Shroom family+++IPR030494///Shroom3+++IPR014800///Apx/Shrm Domain 1+++IPR001478///PDZ domain+++IPR036034///PDZ superfamily","[SHRM3_HUMAN|Reviewed]RecName: Full=Protein Shroom3; AltName: Full=Shroom-related protein; Short=hShrmL;+++[A0A2R8Y5P9_HUMAN|Unreviewed]SubName: Full=Protein Shroom3 {ECO:0000313|Ensembl:ENSP00000494970};+++[A0A2R8Y7T7_HUMAN|Unreviewed]SubName: Full=Protein Shroom3 {ECO:0000313|Ensembl:ENSP00000496523}; Flags: Fragment;+++[B3KY47_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46841 fis, clone UTERU3000670, highly similar to Homo sapiens shroom (SHRM), mRNA {ECO:0000313|EMBL:BAG54709.1};"]
[57643,"'ZSWIM5'",38,64,51,{"$nulls":4},"GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0005615///extracellular space","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:1902667///regulation of axon guidance","IPR007527///Zinc finger, SWIM-type","[ZSWM5_HUMAN|Reviewed]RecName: Full=Zinc finger SWIM domain-containing protein 5;"]
[57664,"'PLEKHA4'",441,444,442.5,"04137///Mitophagy - animal+++04141///Protein processing in endoplasmic reticulum+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005575///cellular_component","GO:0032266///phosphatidylinositol-3-phosphate binding+++GO:0008289///lipid binding","GO:0008150///biological_process+++GO:0006661///phosphatidylinositol biosynthetic process","IPR011993///PH-like domain superfamily+++IPR001849///Pleckstrin homology domain","[PKHA4_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family A member 4; Short=PH domain-containing family A member 4; AltName: Full=Phosphoinositol 3-phosphate-binding protein 1; Short=PEPP-1;+++[M0QXD9_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 4 {ECO:0000313|Ensembl:ENSP00000469096}; Flags: Fragment;+++[M0QXJ3_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 4 {ECO:0000313|Ensembl:ENSP00000469211}; Flags: Fragment;+++[M0R0J1_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 4 {ECO:0000313|Ensembl:ENSP00000471274}; Flags: Fragment;+++[M0R0V1_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 4 {ECO:0000313|Ensembl:ENSP00000471462}; Flags: Fragment;+++[M0R2K5_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 4 {ECO:0000313|Ensembl:ENSP00000472636}; Flags: Fragment;"]
[57687,"'VAT1L'",24,28,26,{"$nulls":5},"GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0008270///zinc ion binding","GO:0055114///oxidation-reduction process","IPR013154///Alcohol dehydrogenase, N-terminal+++IPR036291///NAD(P)-binding domain superfamily+++IPR002364///Quinone oxidoreductase/zeta-crystallin, conserved site+++IPR011032///GroES-like superfamily+++IPR020843///Polyketide synthase, enoylreductase domain","[VAT1L_HUMAN|Reviewed]RecName: Full=Synaptic vesicle membrane protein VAT-1 homolog-like; EC=1.-.-.-;+++[A8K288_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76322 {ECO:0000313|EMBL:BAF82842.1};"]
[57703,"'CWC22'",161,133,147,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0071013///catalytic step 2 spliceosome+++GO:0071006///U2-type catalytic step 1 spliceosome+++GO:0016607///nuclear speck+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0005681///spliceosomal complex","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0008380///RNA splicing+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome","IPR016021///MIF4G-like domain superfamily+++IPR003891///Initiation factor eIF-4 gamma, MA3+++IPR003890///MIF4G-like, type 3+++IPR016024///Armadillo-type fold","[CWC22_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor CWC22 homolog; AltName: Full=Nucampholin homolog; AltName: Full=fSAPb;+++[B7WP74_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor CWC22 homolog {ECO:0000313|Ensembl:ENSP00000384159}; Flags: Fragment;"]
[57719,"'ANO8'",332,422,377,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005788///endoplasmic reticulum lumen+++GO:0016020///membrane","GO:0005229///intracellular calcium activated chloride channel activity","GO:0034220///ion transmembrane transport+++GO:0044267///cellular protein metabolic process+++GO:0006821///chloride transport+++GO:0043687///post-translational protein modification","IPR031289///Anoctamin-8+++IPR007632///Anoctamin","[ANO8_HUMAN|Reviewed]RecName: Full=Anoctamin-8; AltName: Full=Transmembrane protein 16H;+++[M0QYD2_HUMAN|Unreviewed]RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};"]
[57786,"'RBAK'",104.73,152.64,128.685,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated","IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box","[RBAK_HUMAN|Reviewed]RecName: Full=RB-associated KRAB zinc finger protein; AltName: Full=RB-associated KRAB repressor; Short=hRBaK; AltName: Full=Zinc finger protein 769;+++[L8E8N4_HUMAN|Unreviewed]SubName: Full=Alternative protein RBAK {ECO:0000313|EMBL:CCQ43665.1};"]
[57820,"'CCNB1IP1'",172,142,157,"03410///Base excision repair+++04212///Longevity regulating pathway - worm+++04217///Necroptosis+++04210///Apoptosis+++04214///Apoptosis - fly",null,"M00296///BER complex",null,"GO:0000795///synaptonemal complex+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0005694///chromosome","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016740///transferase activity","GO:0016567///protein ubiquitination+++GO:0007131///reciprocal meiotic recombination+++GO:0051026///chiasma assembly+++GO:0001825///blastocyst formation+++GO:0007286///spermatid development+++GO:0051321///meiotic cell cycle","IPR001841///Zinc finger, RING-type","[CIP1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase CCNB1IP1; EC=2.3.2.27 {ECO:0000269|PubMed:12612082}; AltName: Full=Cyclin-B1-interacting protein 1; AltName: Full=Human enhancer of invasion 10; AltName: Full=RING-type E3 ubiquitin transferase CCNB1IP1 {ECO:0000305};+++[G3V5E6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000452312}; Flags: Fragment;+++[G3V5Q4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000452463};+++[G3V5S3_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000452486}; Flags: Fragment;+++[H0YJ70_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000450914}; Flags: Fragment;+++[H0YJB2_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase CCNB1IP1 {ECO:0000313|Ensembl:ENSP00000451122}; Flags: Fragment;"]
[5787,"'PTPRB'",1034,1319.98,1176.99,"04520///Adherens junction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043235///receptor complex+++GO:0035579///specific granule membrane+++GO:0070821///tertiary granule membrane","GO:0004721///phosphoprotein phosphatase activity+++GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity","GO:0043312///neutrophil degranulation+++GO:0001525///angiogenesis+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006796///phosphate-containing compound metabolic process","IPR000387///Tyrosine specific protein phosphatases domain+++IPR000772///Ricin B, lectin domain+++IPR013783///Immunoglobulin-like fold+++IPR003595///Protein-tyrosine phosphatase, catalytic+++IPR016130///Protein-tyrosine phosphatase, active site+++IPR029021///Protein-tyrosine phosphatase-like+++IPR036116///Fibronectin type III superfamily+++IPR003961///Fibronectin type III+++IPR035992///Ricin B-like lectins+++IPR000242///PTP type protein phosphatase","[PTPRB_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase beta; Short=Protein-tyrosine phosphatase beta; Short=R-PTP-beta; EC=3.1.3.48; AltName: Full=Vascular endothelial protein tyrosine phosphatase; Short=VE-PTP; Flags: Precursor;+++[F8VSD5_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase beta {ECO:0000313|Ensembl:ENSP00000448349};+++[F8VU56_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase beta {ECO:0000313|Ensembl:ENSP00000448058};+++[H0YHE8_HUMAN|Unreviewed]RecName: Full=Tyrosine-protein phosphatase {ECO:0000256|RuleBase:RU364084}; EC=3.1.3.48 {ECO:0000256|RuleBase:RU364084}; Flags: Fragment;+++[Q68D73_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686H15164 {ECO:0000313|EMBL:CAH18347.1};+++[Q6ZR19_HUMAN|Unreviewed]SubName: Full=Receptor-type tyrosine-protein phosphatase beta {ECO:0000313|Ensembl:ENSP00000446982}; SubName: Full=cDNA FLJ46721 fis, clone TRACH3018524, highly similar to Protein-tyrosine phosphatase beta {ECO:0000313|EMBL:BAC87502.1}; Flags: Fragment;+++[Q86VA4_HUMAN|Unreviewed]SubName: Full=PTPRB protein {ECO:0000313|EMBL:AAH51329.1};"]
[5800,"'PTPRO'",9,8,8.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01657///Nephrotic syndrome",null,null,"GO:0098978///glutamatergic synapse+++GO:0030424///axon+++GO:0005887///integral component of plasma membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0099061///integral component of postsynaptic density membrane+++GO:0030426///growth cone+++GO:0043197///dendritic spine+++GO:0098982///GABA-ergic synapse+++GO:0016328///lateral plasma membrane+++GO:0030027///lamellipodium+++GO:0016324///apical plasma membrane+++GO:0016021///integral component of membrane+++GO:0043005///neuron projection","GO:0004725///protein tyrosine phosphatase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0017147///Wnt-protein binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0005001///transmembrane receptor protein tyrosine phosphatase activity","GO:0010977///negative regulation of neuron projection development+++GO:0032835///glomerulus development+++GO:0030032///lamellipodium assembly+++GO:0010812///negative regulation of cell-substrate adhesion+++GO:0006310///DNA recombination+++GO:0090260///negative regulation of retinal ganglion cell axon guidance+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0036060///slit diaphragm assembly+++GO:0006470///protein dephosphorylation+++GO:0072112///glomerular visceral epithelial cell differentiation+++GO:0007411///axon guidance+++GO:0002548///monocyte chemotaxis+++GO:0032197///transposition, RNA-mediated+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0003093///regulation of glomerular filtration+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000902///cell morphogenesis+++GO:0003105///negative regulation of glomerular filtration+++GO:0050807///regulation of synapse organization+++GO:0090090///negative regulation of canonical Wnt signaling pathway","IPR016130///Protein-tyrosine phosphatase, active site+++IPR003961///Fibronectin type III+++IPR000242///PTP type protein phosphatase+++IPR013783///Immunoglobulin-like fold+++IPR029021///Protein-tyrosine phosphatase-like+++IPR003595///Protein-tyrosine phosphatase, catalytic+++IPR036116///Fibronectin type III superfamily+++IPR000387///Tyrosine specific protein phosphatases domain","[PTPRO_HUMAN|Reviewed]RecName: Full=Receptor-type tyrosine-protein phosphatase O; Short=R-PTP-O; EC=3.1.3.48; AltName: Full=Glomerular epithelial protein 1; AltName: Full=Protein tyrosine phosphatase U2; Short=PTP-U2; Short=PTPase U2; Flags: Precursor;+++[A0A024RAS0_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase, receptor type, O, isoform CRA_c {ECO:0000313|EMBL:EAW96353.1};+++[A0A024RAS9_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase, receptor type, O, isoform CRA_d {ECO:0000313|EMBL:EAW96352.1};"]
[5819,"'NECTIN2'",7401,6795,7098,"04520///Adherens junction+++05168///Herpes simplex infection+++04514///Cell adhesion molecules (CAMs)",{"$nulls":3},"GO:0009986///cell surface+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0044291///cell-cell contact zone+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005915///zonula adherens+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0043296///apical junction complex","GO:0001618///virus receptor activity+++GO:0050839///cell adhesion molecule binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity+++GO:0015026///coreceptor activity","GO:0042271///susceptibility to natural killer cell mediated cytotoxicity+++GO:0046596///regulation of viral entry into host cell+++GO:0001675///acrosome assembly+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007289///spermatid nucleus differentiation+++GO:0033005///positive regulation of mast cell activation+++GO:0034332///adherens junction organization+++GO:0007286///spermatid development+++GO:0060370///susceptibility to T cell mediated cytotoxicity+++GO:0050776///regulation of immune response+++GO:0030382///sperm mitochondrion organization+++GO:0045954///positive regulation of natural killer cell mediated cytotoxicity+++GO:0016032///viral process+++GO:0032990///cell part morphogenesis+++GO:0007010///cytoskeleton organization+++GO:0009566///fertilization+++GO:0002860///positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target+++GO:0050862///positive regulation of T cell receptor signaling pathway+++GO:0019062///virion attachment to host cell+++GO:0051654///establishment of mitochondrion localization+++GO:0044782///cilium organization+++GO:0002891///positive regulation of immunoglobulin mediated immune response+++GO:0007155///cell adhesion","IPR003599///Immunoglobulin subtype+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR013106///Immunoglobulin V-set domain+++IPR007110///Immunoglobulin-like domain+++IPR013162///CD80-like, immunoglobulin C2-set+++IPR033318///Nectin-2","[NECT2_HUMAN|Reviewed]RecName: Full=Nectin-2; AltName: Full=Herpes virus entry mediator B; Short=Herpesvirus entry mediator B; Short=HveB; AltName: Full=Nectin cell adhesion molecule 2 {ECO:0000312|HGNC:HGNC:9707}; AltName: Full=Poliovirus receptor-related protein 2; AltName: CD_antigen=CD112; Flags: Precursor;+++[K7EK87_HUMAN|Unreviewed]SubName: Full=Nectin-2 {ECO:0000313|Ensembl:ENSP00000465511}; Flags: Fragment;+++[K7EKE8_HUMAN|Unreviewed]SubName: Full=Nectin-2 {ECO:0000313|Ensembl:ENSP00000465587}; Flags: Fragment;+++[K7ERL3_HUMAN|Unreviewed]SubName: Full=Nectin-2 {ECO:0000313|Ensembl:ENSP00000468305}; Flags: Fragment;+++[Q7Z456_HUMAN|Unreviewed]SubName: Full=Poliovirus receptor related 2 {ECO:0000313|EMBL:AAQ19178.1}; Flags: Fragment;+++[Q7Z457_HUMAN|Unreviewed]SubName: Full=Poliovirus receptor related 2 {ECO:0000313|EMBL:AAQ19177.1}; Flags: Fragment;+++[Q7Z458_HUMAN|Unreviewed]SubName: Full=Poliovirus receptor related 2 {ECO:0000313|EMBL:AAQ19176.1}; Flags: Fragment;"]
[58190,"'CTDSP1'",825,949,887,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0070062///extracellular exosome+++GO:0005634///nucleus","GO:0004721///phosphoprotein phosphatase activity+++GO:0016791///phosphatase activity+++GO:0046872///metal ion binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity","GO:0045665///negative regulation of neuron differentiation+++GO:0001933///negative regulation of protein phosphorylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0050768///negative regulation of neurogenesis+++GO:0006470///protein dephosphorylation+++GO:0016311///dephosphorylation+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle","IPR023214///HAD superfamily+++IPR040078///CTD small RNA polymerase II polypeptide A phosphatase-like+++IPR036412///HAD-like superfamily+++IPR011948///Dullard phosphatase domain, eukaryotic+++IPR004274///FCP1 homology domain","[CTDS1_HUMAN|Reviewed]RecName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; EC=3.1.3.16 {ECO:0000269|PubMed:12721286, ECO:0000269|PubMed:17157258}; AltName: Full=Nuclear LIM interactor-interacting factor 3; Short=NLI-IF; Short=NLI-interacting factor 3; AltName: Full=Small C-terminal domain phosphatase 1; Short=SCP1; Short=Small CTD phosphatase 1;+++[A0A024R414_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, isoform CRA_b {ECO:0000313|EMBL:EAW70617.1}; Flags: Fragment;+++[A0A024R461_HUMAN|Unreviewed]SubName: Full=CTD (Carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1, isoform CRA_a {ECO:0000313|EMBL:EAW70618.1};+++[H7C1Z7_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 {ECO:0000313|Ensembl:ENSP00000403256}; Flags: Fragment;+++[H7C270_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 {ECO:0000313|Ensembl:ENSP00000404301}; Flags: Fragment;+++[H7C3E0_HUMAN|Unreviewed]SubName: Full=Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 {ECO:0000313|Ensembl:ENSP00000411308}; Flags: Fragment;"]
[5834,"'PYGB'",1755,1686,1720.5,"02026///Biofilm formation - Escherichia coli+++04922///Glucagon signaling pathway+++04931///Insulin resistance+++04910///Insulin signaling pathway+++00500///Starch and sucrose metabolism+++01100///Metabolic pathways+++04217///Necroptosis+++01110///Biosynthesis of secondary metabolites","H01762///Muscle glycogen storage disease+++H01944///Glycogen storage disease type VI+++H01760///Hepatic glycogen storage disease+++H01943///Glycogen storage disease type V+++H00069///Glycogen storage diseases (GSD)",null,"R02111///1,4-alpha-D-Glucan:orthophosphate alpha-D-glucosyltransferase   Starch + Orthophosphate <=> Amylose + D-Glucose 1-phosphate","GO:0070062///extracellular exosome+++GO:0005576///extracellular region+++GO:0035578///azurophil granule lumen+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0008184///glycogen phosphorylase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0004645///phosphorylase activity+++GO:0005515///protein binding+++GO:0102250///linear malto-oligosaccharide phosphorylase activity+++GO:0102499///SHG alpha-glucan phosphorylase activity+++GO:0016740///transferase activity+++GO:0030170///pyridoxal phosphate binding+++GO:0003824///catalytic activity","GO:0008152///metabolic process+++GO:0005975///carbohydrate metabolic process+++GO:0043312///neutrophil degranulation+++GO:0005977///glycogen metabolic process+++GO:0005980///glycogen catabolic process","IPR011833///Glycogen/starch/alpha-glucan phosphorylase+++IPR035090///Phosphorylase pyridoxal-phosphate attachment site+++IPR000811///Glycosyl transferase, family 35","[PYGB_HUMAN|Reviewed]RecName: Full=Glycogen phosphorylase, brain form {ECO:0000303|PubMed:3346228}; EC=2.4.1.1 {ECO:0000269|PubMed:27402852};+++[H0Y4Z6_HUMAN|Unreviewed]RecName: Full=Alpha-1,4 glucan phosphorylase {ECO:0000256|RuleBase:RU000587}; EC=2.4.1.1 {ECO:0000256|RuleBase:RU000587}; Flags: Fragment;"]
[58490,"'RPRD1B'",289,429,359,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0005813///centrosome+++GO:0016591///RNA polymerase II, holoenzyme+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000993///RNA polymerase II complex binding+++GO:0042802///identical protein binding","GO:0010564///regulation of cell cycle process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain+++GO:0008284///positive regulation of cell proliferation","IPR006569///CID domain+++IPR032337///Cell-cycle alteration and expression-elevated protein in tumour+++IPR008942///ENTH/VHS+++IPR006903///RNA polymerase II-binding domain","[RPR1B_HUMAN|Reviewed]RecName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B; AltName: Full=Cell cycle-related and expression-elevated protein in tumor;+++[A0A087WUK3_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000478724}; Flags: Fragment;+++[A0A087X2D2_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000484897}; Flags: Fragment;+++[A2A2M0_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000416420}; Flags: Fragment;+++[E9PIQ9_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000433947};+++[E9PQF3_HUMAN|Unreviewed]SubName: Full=Regulation of nuclear pre-mRNA domain-containing protein 1B {ECO:0000313|Ensembl:ENSP00000436816};"]
[58509,"'CACTIN'",697,547,622,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0071013///catalytic step 2 spliceosome+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0071347///cellular response to interleukin-1+++GO:0045087///innate immune response+++GO:0007275///multicellular organism development+++GO:0032720///negative regulation of tumor necrosis factor production+++GO:0071222///cellular response to lipopolysaccharide+++GO:0060339///negative regulation of type I interferon-mediated signaling pathway+++GO:0002376///immune system process+++GO:0031665///negative regulation of lipopolysaccharide-mediated signaling pathway+++GO:0008380///RNA splicing+++GO:0032688///negative regulation of interferon-beta production+++GO:0032717///negative regulation of interleukin-8 production+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0006397///mRNA processing+++GO:0034122///negative regulation of toll-like receptor signaling pathway+++GO:0071356///cellular response to tumor necrosis factor+++GO:0000398///mRNA splicing, via spliceosome+++GO:0001933///negative regulation of protein phosphorylation","IPR018816///Cactin, central domain+++IPR019134///Cactin, C-terminal","[CATIN_HUMAN|Reviewed]RecName: Full=Cactin; AltName: Full=Renal carcinoma antigen NY-REN-24;+++[K7EIU6_HUMAN|Unreviewed]SubName: Full=Cactin {ECO:0000313|Ensembl:ENSP00000464898}; Flags: Fragment;+++[K7EMQ0_HUMAN|Unreviewed]SubName: Full=Cactin {ECO:0000313|Ensembl:ENSP00000466600}; Flags: Fragment;+++[K7ENY9_HUMAN|Unreviewed]SubName: Full=Cactin {ECO:0000313|Ensembl:ENSP00000467149}; Flags: Fragment;+++[K7EQE3_HUMAN|Unreviewed]SubName: Full=Cactin {ECO:0000313|Ensembl:ENSP00000467788}; Flags: Fragment;"]
[5860,"'QDPR'",493,315,404,"00790///Folate biosynthesis+++01100///Metabolic pathways","H00167///Phenylketonuria (PKU)",null,"R01793///5,6,7,8-tetrahydrobiopterin:NAD+ oxidoreductase   Dihydrobiopterin + NADH + H+ <=> Tetrahydrobiopterin + NAD++++R01794///5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase   Dihydrobiopterin + NADPH + H+ <=> Tetrahydrobiopterin + NADP+","GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0043005///neuron projection+++GO:0005737///cytoplasm","GO:0070402///NADPH binding+++GO:0009055///electron transfer activity+++GO:0004155///6,7-dihydropteridine reductase activity+++GO:0070404///NADH binding+++GO:0016491///oxidoreductase activity+++GO:0042803///protein homodimerization activity","GO:0010044///response to aluminum ion+++GO:0001889///liver development+++GO:0010288///response to lead ion+++GO:0055114///oxidation-reduction process+++GO:0006729///tetrahydrobiopterin biosynthetic process+++GO:0006559///L-phenylalanine catabolic process+++GO:0006520///cellular amino acid metabolic process+++GO:0022900///electron transport chain+++GO:0051066///dihydrobiopterin metabolic process+++GO:0035690///cellular response to drug+++GO:0033762///response to glucagon","IPR020904///Short-chain dehydrogenase/reductase, conserved site+++IPR002347///Short-chain dehydrogenase/reductase SDR+++IPR036291///NAD(P)-binding domain superfamily","[DHPR_HUMAN|Reviewed]RecName: Full=Dihydropteridine reductase; EC=1.5.1.34; AltName: Full=HDHPR; AltName: Full=Quinoid dihydropteridine reductase; AltName: Full=Short chain dehydrogenase/reductase family 33C member 1;+++[A0A140VKA9_HUMAN|Unreviewed]SubName: Full=Testis secretory sperm-binding protein Li 236P {ECO:0000313|EMBL:AEE61246.1};+++[B7Z415_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000422759}; SubName: Full=Quinoid dihydropteridine reductase, isoform CRA_c {ECO:0000313|EMBL:EAW92776.1}; SubName: Full=cDNA FLJ55000, highly similar to Dihydropteridine reductase {ECO:0000313|EMBL:BAH12401.1};+++[D6RGG7_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000426377};+++[D6RHJ7_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000426039};+++[H0Y8F7_HUMAN|Unreviewed]SubName: Full=Dihydropteridine reductase {ECO:0000313|Ensembl:ENSP00000420873}; Flags: Fragment;"]
[5874,"'RAB27B'",7,24,15.5,"04972///Pancreatic secretion",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0032585///multivesicular body membrane+++GO:0030141///secretory granule+++GO:0031088///platelet dense granule membrane+++GO:0005886///plasma membrane+++GO:0098993///anchored component of synaptic vesicle membrane+++GO:0016324///apical plasma membrane+++GO:0005794///Golgi apparatus+++GO:1904115///axon cytoplasm+++GO:0016020///membrane+++GO:0030667///secretory granule membrane+++GO:0042470///melanosome+++GO:0005795///Golgi stack+++GO:0030140///trans-Golgi network transport vesicle+++GO:0042589///zymogen granule membrane","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0031489///myosin V binding+++GO:0019904///protein domain specific binding+++GO:0019003///GDP binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity","GO:0045921///positive regulation of exocytosis+++GO:0048488///synaptic vesicle endocytosis+++GO:0017157///regulation of exocytosis+++GO:0032402///melanosome transport+++GO:0071985///multivesicular body sorting pathway+++GO:0099641///anterograde axonal protein transport+++GO:0006886///intracellular protein transport+++GO:0032482///Rab protein signal transduction+++GO:0002576///platelet degranulation","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR005225///Small GTP-binding protein domain+++IPR001806///Small GTPase","[RB27B_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-27B; AltName: Full=C25KG;+++[K7EJ38_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-27B {ECO:0000313|Ensembl:ENSP00000465009}; Flags: Fragment;+++[K7ES41_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-27B {ECO:0000313|Ensembl:ENSP00000468542}; Flags: Fragment;"]
[5891,"'MOK'",168,139,153.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0097546///ciliary base+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005929///cilium","GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0004672///protein kinase activity","GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0010468///regulation of gene expression+++GO:0051726///regulation of cell cycle+++GO:0035556///intracellular signal transduction+++GO:0016310///phosphorylation","IPR008271///Serine/threonine-protein kinase, active site+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site","[MOK_HUMAN|Reviewed]RecName: Full=MAPK/MAK/MRK overlapping kinase; EC=2.7.11.22 {ECO:0000250|UniProtKB:Q9WVS4}; AltName: Full=MOK protein kinase; AltName: Full=Renal tumor antigen 1; Short=RAGE-1;+++[B5A978_HUMAN|Unreviewed]SubName: Full=Soluble RAGE variant 1 {ECO:0000313|EMBL:ACF47652.1};+++[B5A979_HUMAN|Unreviewed]SubName: Full=Soluble RAGE variant 2 {ECO:0000313|EMBL:ACF47653.1};+++[B5A980_HUMAN|Unreviewed]SubName: Full=Soluble RAGE variant 3 {ECO:0000313|EMBL:ACF47654.1};+++[B5A981_HUMAN|Unreviewed]SubName: Full=Soluble RAGE variant 4 {ECO:0000313|EMBL:ACF47655.1};+++[E5RFX9_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000427884};+++[E5RHT7_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000429672};+++[E5RHY4_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000429570};+++[E5RI85_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000429511};+++[H0YBV8_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000430416}; Flags: Fragment;+++[H0YKX6_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000452978};+++[H0YLZ5_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000453401};+++[H0YM36_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000453449}; Flags: Fragment;+++[H0YMY9_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000453799}; Flags: Fragment;+++[H3BNF8_HUMAN|Unreviewed]SubName: Full=MAPK/MAK/MRK overlapping kinase {ECO:0000313|Ensembl:ENSP00000454829};+++[O95794_HUMAN|Unreviewed]SubName: Full=Advanced glycosylation end product-specific receptor {ECO:0000313|EMBL:AAD15887.1}; Flags: Fragment;+++[O95795_HUMAN|Unreviewed]SubName: Full=Advanced glycosylation end product-specific receptor {ECO:0000313|EMBL:AAD15888.1}; Flags: Fragment;+++[Q49A77_HUMAN|Unreviewed]SubName: Full=RAGE protein {ECO:0000313|EMBL:AAH43179.1}; SubName: Full=Renal tumor antigen, isoform CRA_e {ECO:0000313|EMBL:EAW81776.1};+++[Q71UQ2_HUMAN|Unreviewed]SubName: Full=Advanced glycosylation end product-specific receptor {ECO:0000313|EMBL:AAD15889.1}; Flags: Fragment;+++[Q9UQR5_HUMAN|Unreviewed]SubName: Full=Receptor for advanced glycosylation end product {ECO:0000313|EMBL:CAB43094.1}; Flags: Fragment;"]
[5905,"'RANGAP1'",2765,2267,2516,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0005643///nuclear pore+++GO:0000775///chromosome, centromeric region+++GO:0016235///aggresome+++GO:0005819///spindle+++GO:1904115///axon cytoplasm+++GO:0000777///condensed chromosome kinetochore+++GO:0030425///dendrite+++GO:0072686///mitotic spindle+++GO:0031965///nuclear membrane+++GO:0005635///nuclear envelope+++GO:0000776///kinetochore+++GO:0048471///perinuclear region of cytoplasm+++GO:0005856///cytoskeleton+++GO:0044614///nuclear pore cytoplasmic filaments+++GO:1990723///cytoplasmic periphery of the nuclear pore complex","GO:0008536///Ran GTPase binding+++GO:0003723///RNA binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0031625///ubiquitin protein ligase binding","GO:0007165///signal transduction+++GO:1904117///cellular response to vasopressin+++GO:0046826///negative regulation of protein export from nucleus+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0048678///response to axon injury+++GO:0043547///positive regulation of GTPase activity+++GO:0090630///activation of GTPase activity","IPR001611///Leucine-rich repeat+++IPR009109///Ran-GTPase activating protein 1, C-terminal+++IPR032675///Leucine-rich repeat domain superfamily+++IPR027038///Ran GTPase-activating protein+++IPR036720///Ran-GTPase activating protein 1, C-terminal domain superfamily","[RAGP1_HUMAN|Reviewed]RecName: Full=Ran GTPase-activating protein 1; Short=RanGAP1;+++[A0A024R1U0_HUMAN|Unreviewed]SubName: Full=Ran GTPase activating protein 1, isoform CRA_d {ECO:0000313|EMBL:EAW60424.1};+++[B0QYT4_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000394787}; Flags: Fragment;+++[B0QYT5_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000408743}; Flags: Fragment;+++[B0QYT6_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000404842}; Flags: Fragment;+++[H0Y4Q3_HUMAN|Unreviewed]SubName: Full=Ran GTPase-activating protein 1 {ECO:0000313|Ensembl:ENSP00000393407}; Flags: Fragment;+++[Q9BSK3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAH04990.1}; Flags: Fragment;"]
[5921,"'RASA1'",459,652,555.5,"04014///Ras signaling pathway+++04013///MAPK signaling pathway - fly+++04010///MAPK signaling pathway+++04360///Axon guidance","H00532///Parkes Weber syndrome+++H02043///Capillary malformation-arteriovenous malformation","M00290///Holo-TFIIH complex",null,"GO:0005675///transcription factor TFIIH holo complex+++GO:0031235///intrinsic component of the cytoplasmic side of the plasma membrane+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0019907///cyclin-dependent protein kinase activating kinase holoenzyme complex+++GO:0001726///ruffle+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0070985///transcription factor TFIIK complex","GO:0016301///kinase activity+++GO:0003924///GTPase activity+++GO:0051020///GTPase binding+++GO:0001784///phosphotyrosine residue binding+++GO:0005102///signaling receptor binding+++GO:0005096///GTPase activator activity+++GO:0019870///potassium channel inhibitor activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity","GO:0007165///signal transduction+++GO:0001570///vasculogenesis+++GO:0030833///regulation of actin filament polymerization+++GO:0008360///regulation of cell shape+++GO:0035556///intracellular signal transduction+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0048514///blood vessel morphogenesis+++GO:0050821///protein stabilization+++GO:0006468///protein phosphorylation+++GO:0000165///MAPK cascade+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:1901409///positive regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0048013///ephrin receptor signaling pathway+++GO:0007162///negative regulation of cell adhesion+++GO:0043066///negative regulation of apoptotic process+++GO:0006368///transcription elongation from RNA polymerase II promoter+++GO:0006363///termination of RNA polymerase I transcription+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000281///mitotic cytokinesis+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0051252///regulation of RNA metabolic process+++GO:0006370///7-methylguanosine mRNA capping+++GO:0007049///cell cycle+++GO:0006366///transcription by RNA polymerase II+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006367///transcription initiation from RNA polymerase II promoter","IPR035841///Ras GTPase-activating protein 1, N-terminal SH2 domain+++IPR035842///Ras GTPase-activating protein 1, C-terminal SH2 domain+++IPR036860///SH2 domain superfamily+++IPR000980///SH2 domain+++IPR035892///C2 domain superfamily+++IPR035652///RasGAP, SH3 domain+++IPR028554///Ras GTPase-activating protein 1+++IPR011993///PH-like domain superfamily+++IPR000008///C2 domain+++IPR023152///Ras GTPase-activating protein, conserved site+++IPR001849///Pleckstrin homology domain+++IPR036028///SH3-like domain superfamily+++IPR008936///Rho GTPase activation protein+++IPR001452///SH3 domain+++IPR001936///Ras GTPase-activating domain+++IPR039360///Ras GTPase-activating protein","[RASA1_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein 1; Short=GAP; Short=GTPase-activating protein; Short=RasGAP; AltName: Full=Ras p21 protein activator; AltName: Full=p120GAP;+++[Q59GK3_HUMAN|Unreviewed]SubName: Full=RAS p21 protein activator 1 isoform 1 variant {ECO:0000313|EMBL:BAD92343.1}; Flags: Fragment;"]
[59285,"'CACNG6'",15,8,11.5,"04010///MAPK signaling pathway+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++05410///Hypertrophic cardiomyopathy (HCM)+++04921///Oxytocin signaling pathway+++05414///Dilated cardiomyopathy (DCM)+++04260///Cardiac muscle contraction+++04261///Adrenergic signaling in cardiomyocytes",{"$nulls":3},"GO:0005891///voltage-gated calcium channel complex+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:1990454///L-type voltage-gated calcium channel complex+++GO:0016021///integral component of membrane","GO:0005262///calcium channel activity+++GO:0005246///calcium channel regulator activity+++GO:0005244///voltage-gated ion channel activity+++GO:0005245///voltage-gated calcium channel activity","GO:0006811///ion transport+++GO:0006816///calcium ion transport+++GO:0034765///regulation of ion transmembrane transport+++GO:0070588///calcium ion transmembrane transport","IPR008368///Voltage-dependent calcium channel, gamma subunit+++IPR004031///PMP-22/EMP/MP20/Claudin superfamily+++IPR008370///Voltage-dependent calcium channel, gamma-6 subunit","[CCG6_HUMAN|Reviewed]RecName: Full=Voltage-dependent calcium channel gamma-6 subunit; AltName: Full=Neuronal voltage-gated calcium channel gamma-6 subunit;+++[A6NFR2_HUMAN|Unreviewed]RecName: Full=Voltage-dependent calcium channel gamma-6 subunit {ECO:0000256|RuleBase:RU363085};+++[A6NP74_HUMAN|Unreviewed]SubName: Full=Calcium channel, voltage-dependent, gamma subunit 6, isoform CRA_c {ECO:0000313|EMBL:EAW72172.1}; SubName: Full=Voltage-dependent calcium channel gamma-6 subunit {ECO:0000313|Ensembl:ENSP00000319135};"]
[59342,"'SCPEP1'",319,226,272.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0004180///carboxypeptidase activity+++GO:0016787///hydrolase activity+++GO:0004185///serine-type carboxypeptidase activity+++GO:0008233///peptidase activity","GO:0006508///proteolysis+++GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0097755///positive regulation of blood vessel diameter+++GO:0042573///retinoic acid metabolic process+++GO:0045776///negative regulation of blood pressure","IPR029058///Alpha/Beta hydrolase fold+++IPR018202///Serine carboxypeptidase, serine active site+++IPR001563///Peptidase S10, serine carboxypeptidase","[RISC_HUMAN|Reviewed]RecName: Full=Retinoid-inducible serine carboxypeptidase; EC=3.4.16.-; AltName: Full=Serine carboxypeptidase 1; Flags: Precursor;+++[I3L195_HUMAN|Unreviewed]SubName: Full=Retinoid-inducible serine carboxypeptidase {ECO:0000313|Ensembl:ENSP00000458671};+++[I3L2N6_HUMAN|Unreviewed]SubName: Full=Retinoid-inducible serine carboxypeptidase {ECO:0000313|Ensembl:ENSP00000459807};+++[I3L4Z3_HUMAN|Unreviewed]RecName: Full=Carboxypeptidase {ECO:0000256|RuleBase:RU361156}; EC=3.4.16.- {ECO:0000256|RuleBase:RU361156}; Flags: Fragment;+++[I3L4Z9_HUMAN|Unreviewed]SubName: Full=Retinoid-inducible serine carboxypeptidase {ECO:0000313|Ensembl:ENSP00000461678}; Flags: Fragment;+++[I3L506_HUMAN|Unreviewed]RecName: Full=Carboxypeptidase {ECO:0000256|RuleBase:RU361156}; EC=3.4.16.- {ECO:0000256|RuleBase:RU361156}; Flags: Fragment;+++[Q9H2J9_HUMAN|Unreviewed]SubName: Full=DC39 {ECO:0000313|EMBL:AAG44699.1};"]
[595,"'CCND1'",42756,43057,42906.5,"05226///Gastric cancer+++05215///Prostate cancer+++04371///Apelin signaling pathway+++05216///Thyroid cancer+++04390///Hippo signaling pathway+++04510///Focal adhesion+++05165///Human papillomavirus infection+++04218///Cellular senescence+++05225///Hepatocellular carcinoma+++05163///Human cytomegalovirus infection+++05206///MicroRNAs in cancer+++04934///Cushing's syndrome+++04917///Prolactin signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++01522///Endocrine resistance+++04310///Wnt signaling pathway+++04919///Thyroid hormone signaling pathway+++04630///Jak-STAT signaling pathway+++04110///Cell cycle+++04068///FoxO signaling pathway+++05205///Proteoglycans in cancer+++05219///Bladder cancer+++05416///Viral myocarditis+++04152///AMPK signaling pathway+++05213///Endometrial cancer+++05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++05210///Colorectal cancer+++05220///Chronic myeloid leukemia+++05203///Viral carcinogenesis+++05224///Breast cancer+++05162///Measles+++05222///Small cell lung cancer+++04530///Tight junction+++05221///Acute myeloid leukemia+++05223///Non-small cell lung cancer+++05166///HTLV-I infection+++05218///Melanoma+++05212///Pancreatic cancer+++04115///p53 signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++05214///Glioma+++04921///Oxytocin signaling pathway+++05161///Hepatitis B+++04340///Hedgehog signaling pathway","H00006///Hairy-cell leukemia+++H01464///Mantle cell lymphoma+++H00559///von Hippel-Lindau syndrome+++H00010///Multiple myeloma+++H00031///Breast cancer+++H00055///Laryngeal cancer+++H00017///Esophageal cancer+++H00016///Oral cancer","M00692///Cell cycle - G1/S transition",null,"GO:0017053///transcriptional repressor complex+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005923///bicellular tight junction+++GO:0005622///intracellular+++GO:0016020///membrane+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex","GO:0008134///transcription factor binding+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0070064///proline-rich region binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0019901///protein kinase binding+++GO:0016301///kinase activity+++GO:0005515///protein binding+++GO:0044877///protein-containing complex binding+++GO:0003714///transcription corepressor activity+++GO:0042826///histone deacetylase binding+++GO:0019899///enzyme binding+++GO:0004672///protein kinase activity","GO:0000082///G1/S transition of mitotic cell cycle+++GO:0042493///response to drug+++GO:0000320///re-entry into mitotic cell cycle+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0032355///response to estradiol+++GO:0051301///cell division+++GO:0007595///lactation+++GO:0097421///liver regeneration+++GO:0045444///fat cell differentiation+++GO:0043627///response to estrogen+++GO:0001889///liver development+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0010165///response to X-ray+++GO:0033598///mammary gland epithelial cell proliferation+++GO:0000278///mitotic cell cycle+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0045787///positive regulation of cell cycle+++GO:0071157///negative regulation of cell cycle arrest+++GO:0033327///Leydig cell differentiation+++GO:0045471///response to ethanol+++GO:0007049///cell cycle+++GO:0019221///cytokine-mediated signaling pathway+++GO:0060749///mammary gland alveolus development+++GO:0030968///endoplasmic reticulum unfolded protein response+++GO:0051592///response to calcium ion+++GO:0007088///regulation of mitotic nuclear division+++GO:0071310///cellular response to organic substance+++GO:0008284///positive regulation of cell proliferation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006468///protein phosphorylation+++GO:0033197///response to vitamin E+++GO:0051412///response to corticosterone+++GO:0010039///response to iron ion+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016055///Wnt signaling pathway+++GO:0010033///response to organic substance+++GO:0001934///positive regulation of protein phosphorylation+++GO:0051384///response to glucocorticoid+++GO:0014070///response to organic cyclic compound+++GO:0033601///positive regulation of mammary gland epithelial cell proliferation+++GO:0031100///animal organ regeneration+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0032026///response to magnesium ion+++GO:0010243///response to organonitrogen compound+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0070141///response to UV-A+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0048545///response to steroid hormone+++GO:0044321///response to leptin+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:1900087///positive regulation of G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle","IPR013763///Cyclin-like+++IPR036915///Cyclin-like superfamily+++IPR006671///Cyclin, N-terminal+++IPR004367///Cyclin, C-terminal domain+++IPR015451///Cyclin D+++IPR039361///Cyclin","[CCND1_HUMAN|Reviewed]RecName: Full=G1/S-specific cyclin-D1; AltName: Full=B-cell lymphoma 1 protein; Short=BCL-1; AltName: Full=BCL-1 oncogene; AltName: Full=PRAD1 oncogene;+++[F5H437_HUMAN|Unreviewed]SubName: Full=G1/S-specific cyclin-D1 {ECO:0000313|Ensembl:ENSP00000438482};+++[Q5MGB2_HUMAN|Unreviewed]SubName: Full=Cyclin D1 {ECO:0000313|EMBL:AAV91344.1}; Flags: Fragment;+++[Q6FI00_HUMAN|Unreviewed]SubName: Full=CCND1 protein {ECO:0000313|EMBL:CAG38775.1}; SubName: Full=Cyclin D1 (PRAD1: parathyroid adenomatosis 1) {ECO:0000313|EMBL:AAV38647.1}; SubName: Full=Cyclin D1, isoform CRA_c {ECO:0000313|EMBL:EAW74748.1}; SubName: Full=cDNA, FLJ93625, Homo sapiens cyclin D1 (PRAD1: parathyroid adenomatosis 1) (CCND1),mRNA {ECO:0000313|EMBL:BAG35955.1};"]
[5977,"'DPF2'",1397,1183,1290,{"$nulls":4},"GO:0071565///nBAF complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0000123///histone acetyltransferase complex+++GO:0005634///nucleus","GO:0062072///H3K9me3 modified histone binding+++GO:0042393///histone binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003676///nucleic acid binding+++GO:0070577///lysine-acetylated histone binding","GO:0006325///chromatin organization+++GO:0007399///nervous system development+++GO:0006915///apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:1905454///negative regulation of myeloid progenitor cell differentiation+++GO:0097190///apoptotic signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0016573///histone acetylation","IPR036236///Zinc finger C2H2 superfamily+++IPR001965///Zinc finger, PHD-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR013087///Zinc finger C2H2-type+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR019787///Zinc finger, PHD-finger+++IPR025750///Requiem/DPF N-terminal domain","[REQU_HUMAN|Reviewed]RecName: Full=Zinc finger protein ubi-d4; AltName: Full=Apoptosis response zinc finger protein; AltName: Full=BRG1-associated factor 45D; Short=BAF45D; AltName: Full=D4, zinc and double PHD fingers family 2; AltName: Full=Protein requiem;+++[A0A024R582_HUMAN|Unreviewed]SubName: Full=D4, zinc and double PHD fingers family 2, isoform CRA_a {ECO:0000313|EMBL:EAW74376.1};+++[E9PN04_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ubi-d4 {ECO:0000313|Ensembl:ENSP00000434885};+++[H0YEI1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ubi-d4 {ECO:0000313|Ensembl:ENSP00000435887}; Flags: Fragment;+++[J3KMZ8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein ubi-d4 {ECO:0000313|Ensembl:ENSP00000252268};"]
[5991,"'RFX3'",19,33,26,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005667///transcription factor complex+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0060285///cilium-dependent cell motility+++GO:0072560///type B pancreatic cell maturation+++GO:2000078///positive regulation of type B pancreatic cell development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048469///cell maturation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0031018///endocrine pancreas development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0006351///transcription, DNA-templated+++GO:0007368///determination of left/right symmetry+++GO:0060271///cilium assembly+++GO:0050796///regulation of insulin secretion+++GO:0030154///cell differentiation+++GO:0060287///epithelial cilium movement involved in determination of left/right asymmetry","IPR007668///RFX1 transcription activation region+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR039779///RFX-like DNA-binding protein+++IPR003150///DNA-binding RFX-type winged-helix domain+++IPR036388///Winged helix-like DNA-binding domain superfamily","[RFX3_HUMAN|Reviewed]RecName: Full=Transcription factor RFX3; AltName: Full=Regulatory factor X 3;+++[A9Z1Z2_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000371414};+++[F6UGA0_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000405664}; Flags: Fragment;+++[F6USP3_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000400026}; Flags: Fragment;+++[F6UV76_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000411756}; Flags: Fragment;+++[F6XM74_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000399352}; Flags: Fragment;+++[H0Y790_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000410988}; Flags: Fragment;+++[H0Y7W5_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000415594}; Flags: Fragment;+++[H0Y7Z4_HUMAN|Unreviewed]SubName: Full=Transcription factor RFX3 {ECO:0000313|Ensembl:ENSP00000416189}; Flags: Fragment;"]
[6013,"'RLN1'",0,5,2.5,"04926///Relaxin signaling pathway",{"$nulls":3},"GO:0005576///extracellular region","GO:0005179///hormone activity","GO:0010469///regulation of signaling receptor activity+++GO:0007565///female pregnancy+++GO:0007165///signal transduction","IPR022352///Insulin family+++IPR036438///Insulin-like superfamily+++IPR022421///Relaxin+++IPR022353///Insulin, conserved site+++IPR016179///Insulin-like","[REL1_HUMAN|Reviewed]RecName: Full=Prorelaxin H1; Contains: RecName: Full=Relaxin B chain; Contains: RecName: Full=Relaxin A chain; Flags: Precursor;"]
[6041,"'RNASEL'",79,105,92,"05164///Influenza A+++05168///Herpes simplex infection+++04621///NOD-like receptor signaling pathway+++05160///Hepatitis C",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005759///mitochondrial matrix+++GO:0016363///nuclear matrix+++GO:0005575///cellular_component+++GO:0005739///mitochondrion+++GO:0005829///cytosol","GO:0042802///identical protein binding+++GO:0004672///protein kinase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004540///ribonuclease activity+++GO:0043021///ribonucleoprotein complex binding+++GO:0016787///hydrolase activity+++GO:0019843///rRNA binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding","GO:0060338///regulation of type I interferon-mediated signaling pathway+++GO:0006468///protein phosphorylation+++GO:0051607///defense response to virus+++GO:0060337///type I interferon signaling pathway+++GO:0043488///regulation of mRNA stability+++GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0045071///negative regulation of viral genome replication+++GO:0045444///fat cell differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006397///mRNA processing+++GO:0046326///positive regulation of glucose import+++GO:0006364///rRNA processing","IPR011009///Protein kinase-like domain superfamily+++IPR010513///KEN domain+++IPR000719///Protein kinase domain+++IPR038357///KEN domain superfamily+++IPR002110///Ankyrin repeat+++IPR020683///Ankyrin repeat-containing domain+++IPR018997///PUB domain+++IPR036770///Ankyrin repeat-containing domain superfamily","[RN5A_HUMAN|Reviewed]RecName: Full=2-5A-dependent ribonuclease; Short=2-5A-dependent RNase; EC=3.1.26.-; AltName: Full=Ribonuclease 4; AltName: Full=Ribonuclease L; Short=RNase L;+++[Q1RLL8_HUMAN|Unreviewed]SubName: Full=Ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) {ECO:0000313|EMBL:AAI15698.1};"]
[60491,"'NIF3L1'",169,181,175,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030182///neuron differentiation","IPR017222///NIF3-like protein 1, animal+++IPR036069///GTP cyclohydrolase 1 type 2/Nif3 superfamily+++IPR002678///GTP cyclohydrolase 1 type 2/Nif3","[NIF3L_HUMAN|Reviewed]RecName: Full=NIF3-like protein 1 {ECO:0000305|PubMed:11124544}; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein {ECO:0000303|PubMed:11161814};+++[A0A024R3V5_HUMAN|Unreviewed]RecName: Full=NIF3-like protein 1 {ECO:0000256|PIRNR:PIRNR037490};+++[A0A024R3V7_HUMAN|Unreviewed]RecName: Full=NIF3-like protein 1 {ECO:0000256|PIRNR:PIRNR037490};+++[B8ZZI0_HUMAN|Unreviewed]SubName: Full=NIF3-like protein 1 {ECO:0000313|Ensembl:ENSP00000387061}; Flags: Fragment;+++[C9JN42_HUMAN|Unreviewed]SubName: Full=NIF3-like protein 1 {ECO:0000313|Ensembl:ENSP00000394955}; Flags: Fragment;+++[E7EXA3_HUMAN|Unreviewed]SubName: Full=NIF3-like protein 1 {ECO:0000313|Ensembl:ENSP00000412761}; Flags: Fragment;+++[H7C1A8_HUMAN|Unreviewed]SubName: Full=NIF3-like protein 1 {ECO:0000313|Ensembl:ENSP00000399336}; Flags: Fragment;+++[Q6X734_HUMAN|Unreviewed]RecName: Full=NIF3-like protein 1 {ECO:0000256|PIRNR:PIRNR037490};"]
[60560,"'NAA35'",347,401,374,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031417///NatC complex+++GO:0005844///polysome+++GO:0005737///cytoplasm","GO:0004596///peptide alpha-N-acetyltransferase activity+++GO:0005515///protein binding","GO:0048659///smooth muscle cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0006474///N-terminal protein amino acid acetylation+++GO:0017196///N-terminal peptidyl-methionine acetylation","IPR007244///NatC N(alpha)-terminal acetyltransferase, Mak10 subunit","[NAA35_HUMAN|Reviewed]RecName: Full=N-alpha-acetyltransferase 35, NatC auxiliary subunit; AltName: Full=Embryonic growth-associated protein homolog; AltName: Full=Protein MAK10 homolog;+++[A8K874_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77588, highly similar to Homo sapiens MAK10 homolog, amino-acid N-acetyltransferase subunit, (S. cerevisiae) (MAK10), mRNA {ECO:0000313|EMBL:BAF84928.1};"]
[60682,"'SMAP1'",519,556,537.5,"04144///Endocytosis",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0005096///GTPase activator activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0030276///clathrin binding","GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0045648///positive regulation of erythrocyte differentiation+++GO:0006310///DNA recombination","IPR001164///Arf GTPase activating protein+++IPR038508///ArfGAP domain superfamily+++IPR037278///ARFGAP/RecO-like zinc finger","[SMAP1_HUMAN|Reviewed]RecName: Full=Stromal membrane-associated protein 1;+++[A0A087X1X9_HUMAN|Unreviewed]SubName: Full=Stromal membrane-associated protein 1 {ECO:0000313|Ensembl:ENSP00000484538};+++[H0Y5G0_HUMAN|Unreviewed]SubName: Full=Stromal membrane-associated protein 1 {ECO:0000313|Ensembl:ENSP00000398306}; Flags: Fragment;+++[L0R5C9_HUMAN|Unreviewed]SubName: Full=Alternative protein SMAP1 {ECO:0000313|EMBL:CCO13819.1};+++[Q5T6I8_HUMAN|Unreviewed]SubName: Full=Stromal membrane-associated protein 1 {ECO:0000313|Ensembl:ENSP00000415426}; Flags: Fragment;"]
[6103,"'RPGR'",30,22,26,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00481///Cone-rod dystrophy and cone dystrophy+++H00527///Retinitis pigmentosa (RP)",null,null,"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0005794///Golgi apparatus+++GO:0031514///motile cilium+++GO:0001750///photoreceptor outer segment+++GO:0005929///cilium+++GO:0005856///cytoskeleton+++GO:0036064///ciliary basal body+++GO:0036126///sperm flagellum+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center","GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0003723///RNA binding","GO:0006886///intracellular protein transport+++GO:0042073///intraciliary transport+++GO:0050896///response to stimulus+++GO:0060271///cilium assembly+++GO:0007601///visual perception+++GO:0030030///cell projection organization","IPR009091///Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II+++IPR000408///Regulator of chromosome condensation, RCC1","[RPGR_HUMAN|Reviewed]RecName: Full=X-linked retinitis pigmentosa GTPase regulator; Flags: Precursor;+++[A0A0S2Z4D6_HUMAN|Unreviewed]SubName: Full=Retinitis pigmentosa GTPase regulator isoform 2 {ECO:0000313|EMBL:ALQ33770.1}; Flags: Fragment;+++[A0A0S2Z4Y6_HUMAN|Unreviewed]SubName: Full=Retinitis pigmentosa GTPase regulator isoform 1 {ECO:0000313|EMBL:ALQ33769.1}; SubName: Full=Retinitis pigmentosa GTPase regulator, isoform CRA_c {ECO:0000313|EMBL:EAW59443.1}; Flags: Fragment;+++[A0A2R8Y414_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000493596};+++[A0A2R8Y4C9_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000493681};+++[A0A2R8Y838_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000496446};+++[A0A2R8YDN2_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000494745};+++[A0A2R8YF02_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000496030};+++[A0A2R8YFT6_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000496728};+++[A0A2R8YGY6_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000496427}; Flags: Fragment;+++[H7C4H4_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000417336}; Flags: Fragment;+++[H7C4L1_HUMAN|Unreviewed]SubName: Full=X-linked retinitis pigmentosa GTPase regulator {ECO:0000313|Ensembl:ENSP00000417574}; Flags: Fragment;+++[Q9HD28_HUMAN|Unreviewed]SubName: Full=Retinitis pigmentosa GTPase regulator {ECO:0000313|EMBL:AAG00551.1}; Flags: Fragment;"]
[6132,"'RPL8'",10513,7716,9114.5,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0098794///postsynapse+++GO:0005737///cytoplasm+++GO:0015934///large ribosomal subunit+++GO:0005829///cytosol+++GO:0045202///synapse+++GO:0005840///ribosome+++GO:0016020///membrane+++GO:0005925///focal adhesion+++GO:0022625///cytosolic large ribosomal subunit+++GO:0014069///postsynaptic density+++GO:0042788///polysomal ribosome","GO:0003723///RNA binding+++GO:0019843///rRNA binding+++GO:0003735///structural constituent of ribosome","GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006413///translational initiation+++GO:0006412///translation+++GO:0002181///cytoplasmic translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane","IPR014722///Ribosomal protein L2, domain 2+++IPR023672///Ribosomal protein L2, archaeal-type+++IPR022666///Ribosomal Proteins L2, RNA binding domain+++IPR022671///Ribosomal protein L2, conserved site+++IPR014726///Ribosomal protein L2, domain 3+++IPR008991///Translation protein SH3-like domain superfamily+++IPR022669///Ribosomal protein L2, C-terminal+++IPR002171///Ribosomal protein L2+++IPR012340///Nucleic acid-binding, OB-fold","[RL8_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L8; AltName: Full=Large ribosomal subunit protein uL2 {ECO:0000303|PubMed:24524803};+++[E9PKU4_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L8 {ECO:0000313|Ensembl:ENSP00000435313}; Flags: Fragment;+++[E9PKZ0_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L8 {ECO:0000313|Ensembl:ENSP00000434535}; Flags: Fragment;+++[E9PP36_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L8 {ECO:0000313|Ensembl:ENSP00000436460};+++[G3V1A1_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L8 {ECO:0000313|Ensembl:ENSP00000433703}; SubName: Full=Ribosomal protein L8, isoform CRA_a {ECO:0000313|EMBL:EAW82047.1};+++[H0YF23_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L8 {ECO:0000313|Ensembl:ENSP00000437062}; Flags: Fragment;"]
[6154,"'RPL26'",2798,2199,2498.5,"03010///Ribosome","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0015934///large ribosomal subunit+++GO:0022625///cytosolic large ribosomal subunit+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005840///ribosome+++GO:0005730///nucleolus+++GO:0022626///cytosolic ribosome+++GO:1990904///ribonucleoprotein complex+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0003735///structural constituent of ribosome+++GO:0048027///mRNA 5'-UTR binding+++GO:0003723///RNA binding","GO:1904803///regulation of translation involved in cellular response to UV+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006364///rRNA processing+++GO:0042273///ribosomal large subunit biogenesis+++GO:0002181///cytoplasmic translation+++GO:0045727///positive regulation of translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:1902164///positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator+++GO:0071480///cellular response to gamma radiation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:1902167///positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0034644///cellular response to UV","IPR005756///Ribosomal protein L26/L24, eukaryotic/archaeal+++IPR014722///Ribosomal protein L2, domain 2+++IPR005824///KOW+++IPR008991///Translation protein SH3-like domain superfamily+++IPR005825///Ribosomal protein L24/L26, conserved site","[RL26_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L26; AltName: Full=Large ribosomal subunit protein uL24 {ECO:0000303|PubMed:24524803};+++[J3KS10_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L26 {ECO:0000313|Ensembl:ENSP00000462249}; Flags: Fragment;+++[J3KSS0_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L26 {ECO:0000313|Ensembl:ENSP00000462619};+++[J3QQV1_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L26 {ECO:0000313|Ensembl:ENSP00000463910};+++[J3QRC4_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L26 {ECO:0000313|Ensembl:ENSP00000464143}; Flags: Fragment;+++[J3QRI7_HUMAN|Unreviewed]SubName: Full=60S ribosomal protein L26 {ECO:0000313|Ensembl:ENSP00000464239}; Flags: Fragment;+++[Q6IBH6_HUMAN|Unreviewed]SubName: Full=RPL26 protein {ECO:0000313|EMBL:CAG33109.1};"]
[6170,"'RPL39'",2000,1950,1975,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes+++M00179///Ribosome, archaea",null,"GO:0005829///cytosol+++GO:0022625///cytosolic large ribosomal subunit+++GO:0042788///polysomal ribosome+++GO:0005615///extracellular space+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome+++GO:0003723///RNA binding","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006413///translational initiation+++GO:0002181///cytoplasmic translation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0002227///innate immune response in mucosa+++GO:0006412///translation+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide","IPR023626///Ribosomal protein L39e domain superfamily+++IPR020083///Ribosomal protein L39e, conserved site+++IPR000077///Ribosomal protein L39e","[RL39_HUMAN|Reviewed]RecName: Full=60S ribosomal protein L39; AltName: Full=Large ribosomal subunit protein eL39 {ECO:0000303|PubMed:24524803};"]
[6192,"'RPS4Y1'",1666,1030,1348,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0016020///membrane+++GO:0005840///ribosome+++GO:0005844///polysome+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0022627///cytosolic small ribosomal subunit","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome+++GO:0019843///rRNA binding","GO:0006412///translation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0007275///multicellular organism development+++GO:0006413///translational initiation","IPR000876///Ribosomal protein S4e+++IPR018199///Ribosomal protein S4e, N-terminal, conserved site+++IPR005824///KOW+++IPR013843///Ribosomal protein S4e, N-terminal+++IPR032277///40S ribosomal protein S4, C-terminal domain+++IPR014722///Ribosomal protein L2, domain 2+++IPR013845///Ribosomal protein S4e, central region+++IPR002942///RNA-binding S4 domain+++IPR038237///Ribosomal protein S4e, central domain superfamily","[RS4Y1_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S4, Y isoform 1; AltName: Full=Small ribosomal subunit protein eS4 {ECO:0000303|PubMed:24524803};+++[A4FU11_HUMAN|Unreviewed]SubName: Full=RPS4Y1 protein {ECO:0000313|EMBL:AAI00907.1}; Flags: Fragment;+++[C9JEH7_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S4, Y isoform 1 {ECO:0000313|Ensembl:ENSP00000415317}; Flags: Fragment;+++[Q496E4_HUMAN|Unreviewed]RecName: Full=40S ribosomal protein S4 {ECO:0000256|PIRNR:PIRNR002116};"]
[6206,"'RPS12'",1970,1712,1841,"03010///Ribosome",null,"M00177///Ribosome, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0022627///cytosolic small ribosomal subunit+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005829///cytosol","GO:0003723///RNA binding+++GO:0003735///structural constituent of ribosome","GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006412///translation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006413///translational initiation","IPR004038///Ribosomal protein L7Ae/L30e/S12e/Gadd45+++IPR029064///50S ribosomal protein L30e-like+++IPR000530///Ribosomal protein S12e","[RS12_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S12; AltName: Full=Small ribosomal subunit protein eS12 {ECO:0000303|PubMed:24524803};"]
[6230,"'RPS25'",3998,3711,3854.5,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0005654///nucleoplasm+++GO:0005840///ribosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0070062///extracellular exosome+++GO:0015935///small ribosomal subunit+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005730///nucleolus","GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0006412///translation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006413///translational initiation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR004977///Ribosomal protein S25","[RS25_HUMAN|Reviewed]RecName: Full=40S ribosomal protein S25; AltName: Full=Small ribosomal subunit protein eS25 {ECO:0000303|PubMed:24524803};+++[E9PK60_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S25 {ECO:0000313|Ensembl:ENSP00000431634};+++[E9PQK3_HUMAN|Unreviewed]SubName: Full=40S ribosomal protein S25 {ECO:0000313|Ensembl:ENSP00000436193};"]
[6249,"'CLIP1'",1180,1346,1263,"04150///mTOR signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005882///intermediate filament+++GO:0005856///cytoskeleton+++GO:0044354///macropinosome+++GO:0005874///microtubule+++GO:0001726///ruffle+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0005813///centrosome+++GO:0005881///cytoplasmic microtubule+++GO:0005829///cytosol+++GO:0000776///kinetochore+++GO:0015630///microtubule cytoskeleton+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005768///endosome+++GO:0005635///nuclear envelope+++GO:0035371///microtubule plus-end","GO:0042803///protein homodimerization activity+++GO:0008270///zinc ion binding+++GO:0008017///microtubule binding+++GO:0015631///tubulin binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0051010///microtubule plus-end binding+++GO:0046872///metal ion binding","GO:0031116///positive regulation of microtubule polymerization+++GO:0000278///mitotic cell cycle+++GO:0044861///protein transport into plasma membrane raft+++GO:0001578///microtubule bundle formation","IPR032108///CLIP1, zinc knuckle+++IPR000938///CAP Gly-rich domain+++IPR036859///CAP Gly-rich domain superfamily","[CLIP1_HUMAN|Reviewed]RecName: Full=CAP-Gly domain-containing linker protein 1; AltName: Full=Cytoplasmic linker protein 1; AltName: Full=Cytoplasmic linker protein 170 alpha-2; Short=CLIP-170; AltName: Full=Reed-Sternberg intermediate filament-associated protein; AltName: Full=Restin;+++[A0A024RBR1_HUMAN|Unreviewed]SubName: Full=Restin (Reed-Steinberg cell-expressed intermediate filament-associated protein), isoform CRA_b {ECO:0000313|EMBL:EAW98322.1};+++[B3KXA5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ45045 fis, clone BRAWH3021580, highly similar to Restin (Cytoplasmic linker protein 170 alpha-2) {ECO:0000313|EMBL:BAG54417.1};+++[F5H0N7_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000438743};+++[F5H1T5_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000446379};+++[F5H270_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000439472}; Flags: Fragment;+++[F5H367_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000445387}; Flags: Fragment;+++[F5H6A0_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000437786}; Flags: Fragment;+++[F5H6H4_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000437617};+++[F6VGP8_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000441409}; Flags: Fragment;+++[J3KP58_HUMAN|Unreviewed]SubName: Full=CAP-Gly domain-containing linker protein 1 {ECO:0000313|Ensembl:ENSP00000355314};+++[O43666_HUMAN|Unreviewed]SubName: Full=Cytoplasmic linker protein CLIP-170 {ECO:0000313|EMBL:AAC03549.1}; Flags: Fragment;+++[O43667_HUMAN|Unreviewed]SubName: Full=Cytoplasmic linker protein CLIP-170 {ECO:0000313|EMBL:AAC03550.1}; Flags: Fragment;+++[Q6P5Z9_HUMAN|Unreviewed]SubName: Full=CLIP1 protein {ECO:0000313|EMBL:AAH62543.1}; Flags: Fragment;+++[Q6Q318_HUMAN|Unreviewed]SubName: Full=Restin isoform b {ECO:0000313|EMBL:AAS75590.1}; Flags: Fragment;+++[Q86WU4_HUMAN|Unreviewed]SubName: Full=CLIP1 protein {ECO:0000313|EMBL:AAH47895.1}; Flags: Fragment;"]
[6276,"'S100A5'",0,1,0.5,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0008270///zinc ion binding+++GO:0005507///copper ion binding+++GO:0046914///transition metal ion binding+++GO:0005509///calcium ion binding",null,"IPR034325///S-100+++IPR013787///S100/CaBP-9k-type, calcium binding, subdomain+++IPR002048///EF-hand domain+++IPR028497///Protein S100-A5+++IPR011992///EF-hand domain pair+++IPR018247///EF-Hand 1, calcium-binding site+++IPR001751///S100/Calbindin-D9k, conserved site","[S10A5_HUMAN|Reviewed]RecName: Full=Protein S100-A5; AltName: Full=Protein S-100D; AltName: Full=S100 calcium-binding protein A5;"]
[6302,"'TSPAN31'",232,183,207.5,"04068///FoxO signaling pathway+++04144///Endocytosis","H00036///Osteosarcoma",null,null,"GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane","GO:0005525///GTP binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0003924///GTPase activity+++GO:0005096///GTPase activator activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0044877///protein-containing complex binding+++GO:0030332///cyclin binding","GO:0007166///cell surface receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation","IPR000301///Tetraspanin+++IPR018499///Tetraspanin/Peripherin","[TSN31_HUMAN|Reviewed]RecName: Full=Tetraspanin-31; Short=Tspan-31; AltName: Full=Sarcoma-amplified sequence;+++[B4DFJ7_HUMAN|Unreviewed]SubName: Full=Tetraspanin 31, isoform CRA_a {ECO:0000313|EMBL:EAW97054.1}; SubName: Full=cDNA FLJ55837, highly similar to Tetraspanin-31 {ECO:0000313|EMBL:BAG57458.1};+++[F8VNT7_HUMAN|Unreviewed]SubName: Full=Tetraspanin-31 {ECO:0000313|Ensembl:ENSP00000450195};+++[F8VP43_HUMAN|Unreviewed]SubName: Full=Tetraspanin-31 {ECO:0000313|Ensembl:ENSP00000446482};+++[F8VS78_HUMAN|Unreviewed]SubName: Full=Tetraspanin-31 {ECO:0000313|Ensembl:ENSP00000448209};+++[F8VVF8_HUMAN|Unreviewed]SubName: Full=Tetraspanin-31 {ECO:0000313|Ensembl:ENSP00000449312}; Flags: Fragment;+++[F8VW54_HUMAN|Unreviewed]SubName: Full=Tetraspanin-31 {ECO:0000313|Ensembl:ENSP00000449131}; Flags: Fragment;+++[F8VWE0_HUMAN|Unreviewed]SubName: Full=Tetraspanin-31 {ECO:0000313|Ensembl:ENSP00000449199};"]
[6324,"'SCN1B'",230,176,203,"04261///Adrenergic signaling in cardiomyocytes","H00731///Atrial fibrillation+++H00783///Febrile seizures+++H00728///Brugada syndrome (BRS)",null,null,"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0030315///T-tubule+++GO:0033268///node of Ranvier+++GO:0014704///intercalated disc+++GO:0005576///extracellular region+++GO:0001518///voltage-gated sodium channel complex+++GO:0034706///sodium channel complex","GO:0044325///ion channel binding+++GO:0005248///voltage-gated sodium channel activity+++GO:0086062///voltage-gated sodium channel activity involved in Purkinje myocyte action potential+++GO:0005515///protein binding+++GO:0005272///sodium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:0086006///voltage-gated sodium channel activity involved in cardiac muscle cell action potential+++GO:0019871///sodium channel inhibitor activity+++GO:0017080///sodium channel regulator activity","GO:0007155///cell adhesion+++GO:0019227///neuronal action potential propagation+++GO:0006811///ion transport+++GO:0051899///membrane depolarization+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0086047///membrane depolarization during Purkinje myocyte cell action potential+++GO:0035725///sodium ion transmembrane transport+++GO:0007411///axon guidance+++GO:0002028///regulation of sodium ion transport+++GO:0010976///positive regulation of neuron projection development+++GO:0086012///membrane depolarization during cardiac muscle cell action potential+++GO:0006814///sodium ion transport+++GO:2000649///regulation of sodium ion transmembrane transporter activity+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0034765///regulation of ion transmembrane transport+++GO:0046684///response to pyrethroid+++GO:0021966///corticospinal neuron axon guidance+++GO:0061337///cardiac conduction+++GO:0060371///regulation of atrial cardiac muscle cell membrane depolarization+++GO:0007268///chemical synaptic transmission+++GO:0010765///positive regulation of sodium ion transport+++GO:0040011///locomotion+++GO:0060048///cardiac muscle contraction","IPR013106///Immunoglobulin V-set domain+++IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR027098///Sodium channel subunit beta-1/beta-3","[SCN1B_HUMAN|Reviewed]RecName: Full=Sodium channel subunit beta-1; Flags: Precursor;+++[A0A1W2PR05_HUMAN|Unreviewed]SubName: Full=Sodium channel subunit beta-1 {ECO:0000313|Ensembl:ENSP00000492247};+++[A0A1W2PS68_HUMAN|Unreviewed]SubName: Full=Sodium channel subunit beta-1 {ECO:0000313|Ensembl:ENSP00000492655};+++[B4DI92_HUMAN|Unreviewed]SubName: Full=Sodium channel subunit beta-1 {ECO:0000313|Ensembl:ENSP00000468848}; SubName: Full=cDNA FLJ55064, moderately similar to Sodium channel beta-1 subunit {ECO:0000313|EMBL:BAG58404.1};+++[Q2KHR9_HUMAN|Unreviewed]SubName: Full=SCN1B protein {ECO:0000313|EMBL:AAI12923.1};+++[Q8WU42_HUMAN|Unreviewed]SubName: Full=SCN1B protein {ECO:0000313|EMBL:AAH21266.2}; Flags: Fragment;"]
[6342,"'SCP2'",567,605,586,"03320///PPAR signaling pathway+++00120///Primary bile acid biosynthesis+++01100///Metabolic pathways+++04146///Peroxisome","H00874///Leukoencephalopathy with dystonia and motor neuropathy+++H00407///Peroxisomal beta-oxidation enzyme deficiency","M00104///Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate","R04811///Propanoyl-CoA:acetyl-CoA C-acyltransferase; 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA; C-acyltransferase   Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-24-oxocholestanoyl-CoA+++R03719///3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase; choloyl-CoA:propanoyl-CoA   Propanoyl-CoA + Choloyl-CoA <=> CoA + 3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA","GO:0005782///peroxisomal matrix+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005777///peroxisome+++GO:0032991///protein-containing complex+++GO:0005739///mitochondrion","GO:0050632///propionyl-CoA C2-trimethyltridecanoyltransferase activity+++GO:0008526///phosphatidylinositol transporter activity+++GO:0070538///oleic acid binding+++GO:0036042///long-chain fatty acyl-CoA binding+++GO:0000062///fatty-acyl-CoA binding+++GO:0033814///propanoyl-CoA C-acyltransferase activity+++GO:0015485///cholesterol binding+++GO:0015248///sterol transporter activity+++GO:0005102///signaling receptor binding","GO:0006625///protein targeting to peroxisome+++GO:0032959///inositol trisphosphate biosynthetic process+++GO:0032385///positive regulation of intracellular cholesterol transport+++GO:0036109///alpha-linolenic acid metabolic process+++GO:1901373///lipid hydroperoxide transport+++GO:0006694///steroid biosynthetic process+++GO:0015914///phospholipid transport+++GO:0006701///progesterone biosynthetic process+++GO:0006699///bile acid biosynthetic process+++GO:0033540///fatty acid beta-oxidation using acyl-CoA oxidase+++GO:0045940///positive regulation of steroid metabolic process+++GO:0072659///protein localization to plasma membrane","IPR020613///Thiolase, conserved site+++IPR020615///Thiolase, acyl-enzyme intermediate active site+++IPR020616///Thiolase, N-terminal+++IPR003033///SCP2 sterol-binding domain+++IPR020617///Thiolase, C-terminal+++IPR002155///Thiolase+++IPR036527///SCP2 sterol-binding domain superfamily+++IPR016039///Thiolase-like","[NLTP_HUMAN|Reviewed]RecName: Full=Non-specific lipid-transfer protein; Short=NSL-TP; EC=2.3.1.176; AltName: Full=Propanoyl-CoA C-acyltransferase; AltName: Full=SCP-chi; AltName: Full=SCPX; AltName: Full=Sterol carrier protein 2; Short=SCP-2; AltName: Full=Sterol carrier protein X; Short=SCP-X;+++[B2R761_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93299, highly similar to Homo sapiens sterol carrier protein 2 (SCP2), mRNA {ECO:0000313|EMBL:BAG35708.1};+++[E9PLD1_HUMAN|Unreviewed]SubName: Full=Non-specific lipid-transfer protein {ECO:0000313|Ensembl:ENSP00000435194};+++[Q59HG9_HUMAN|Unreviewed]SubName: Full=Sterol carrier protein X isoform 1 proprotein variant {ECO:0000313|EMBL:BAD92026.1}; Flags: Fragment;"]
[6374,"'CXCL5'",2,3,2.5,"05323///Rheumatoid arthritis+++04062///Chemokine signaling pathway+++04657///IL-17 signaling pathway+++05133///Pertussis+++04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0008009///chemokine activity+++GO:0005125///cytokine activity+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0006954///inflammatory response+++GO:0061844///antimicrobial humoral immune response mediated by antimicrobial peptide+++GO:0030595///leukocyte chemotaxis+++GO:0060326///cell chemotaxis+++GO:0008284///positive regulation of cell proliferation+++GO:0070098///chemokine-mediated signaling pathway+++GO:0006955///immune response+++GO:0007267///cell-cell signaling+++GO:0007165///signal transduction+++GO:0006952///defense response+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0006935///chemotaxis+++GO:0010469///regulation of signaling receptor activity+++GO:0030593///neutrophil chemotaxis","IPR036048///Chemokine interleukin-8-like superfamily+++IPR033899///CXC Chemokine domain+++IPR001089///CXC chemokine+++IPR001811///Chemokine interleukin-8-like domain+++IPR018048///CXC chemokine, conserved site","[CXCL5_HUMAN|Reviewed]RecName: Full=C-X-C motif chemokine 5; AltName: Full=ENA-78(1-78); AltName: Full=Epithelial-derived neutrophil-activating protein 78; AltName: Full=Neutrophil-activating peptide ENA-78; AltName: Full=Small-inducible cytokine B5; Contains: RecName: Full=ENA-78(8-78); Contains: RecName: Full=ENA-78(9-78); Flags: Precursor;+++[Q6I9S7_HUMAN|Unreviewed]RecName: Full=C-X-C motif chemokine {ECO:0000256|RuleBase:RU361149};"]
[6389,"'SDHA'",1859,1510,1684.5,"01110///Biosynthesis of secondary metabolites+++01100///Metabolic pathways+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04714///Thermogenesis+++00190///Oxidative phosphorylation+++05016///Huntington's disease+++01200///Carbon metabolism+++01130///Biosynthesis of antibiotics+++01120///Microbial metabolism in diverse environments+++05010///Alzheimer's disease+++00020///Citrate cycle (TCA cycle)+++05012///Parkinson's disease","H01354///Leigh syndrome+++H01022///Diseases of the tricarboxylic acid cycle+++H00294///Dilated cardiomyopathy (DCM)+++H02005///Mitochondrial complex II deficiency","M00011///Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate+++M00148///Succinate dehydrogenase (ubiquinone)+++M00009///Citrate cycle (TCA cycle, Krebs cycle)","R02164///succinate:quinone oxidoreductase   Quinone + Succinate <=> Hydroquinone + Fumarate","GO:0005730///nucleolus+++GO:0043209///myelin sheath+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0045282///plasma membrane succinate dehydrogenase complex+++GO:0005749///mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)+++GO:0005743///mitochondrial inner membrane","GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0008177///succinate dehydrogenase (ubiquinone) activity+++GO:0000104///succinate dehydrogenase activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0009055///electron transfer activity","GO:0006121///mitochondrial electron transport, succinate to ubiquinone+++GO:0009061///anaerobic respiration+++GO:0006099///tricarboxylic acid cycle+++GO:0055114///oxidation-reduction process+++GO:0022900///electron transport chain+++GO:0007399///nervous system development+++GO:0006105///succinate metabolic process+++GO:0022904///respiratory electron transport chain","IPR003952///Fumarate reductase/succinate dehydrogenase, FAD-binding site+++IPR011281///Succinate dehydrogenase, flavoprotein subunit+++IPR015939///Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal+++IPR027477///Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily+++IPR014006///Succinate dehydrogenase/fumarate reductase, flavoprotein subunit+++IPR003953///FAD-dependent oxidoreductase 2, FAD binding domain+++IPR036188///FAD/NAD(P)-binding domain superfamily+++IPR037099///Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily","[SDHA_HUMAN|Reviewed]RecName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; EC=1.3.5.1 {ECO:0000305|PubMed:24781757}; AltName: Full=Flavoprotein subunit of complex II; Short=Fp; Flags: Precursor;+++[A0A024QZ30_HUMAN|Unreviewed]RecName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial {ECO:0000256|RuleBase:RU362051}; EC=1.3.5.1 {ECO:0000256|RuleBase:RU362051};+++[A0A087X1I3_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000484230};+++[D6REB7_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000425077};+++[D6RFM5_HUMAN|Unreviewed]RecName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial {ECO:0000256|RuleBase:RU362051}; EC=1.3.5.1 {ECO:0000256|RuleBase:RU362051};+++[H0Y8S2_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000421911}; Flags: Fragment;+++[H0Y8X1_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000422404}; Flags: Fragment;+++[Q0QF12_HUMAN|Unreviewed]RecName: Full=Succinate dehydrogenase (quinone) {ECO:0000256|RuleBase:RU362051}; EC=1.3.5.1 {ECO:0000256|RuleBase:RU362051}; Flags: Fragment;"]
[6391,"'SDHC'",691,729,710,"05016///Huntington's disease+++01200///Carbon metabolism+++00020///Citrate cycle (TCA cycle)+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++00190///Oxidative phosphorylation+++01120///Microbial metabolism in diverse environments+++01110///Biosynthesis of secondary metabolites+++05010///Alzheimer's disease+++04714///Thermogenesis+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease","H01510///Malignant paraganglioma","M00011///Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate+++M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00148///Succinate dehydrogenase (ubiquinone)","R02164///succinate:quinone oxidoreductase   Quinone + Succinate <=> Hydroquinone + Fumarate","GO:0005739///mitochondrion+++GO:0045273///respiratory chain complex II+++GO:0005749///mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0045281///succinate dehydrogenase complex+++GO:0005743///mitochondrial inner membrane","GO:0020037///heme binding+++GO:0000104///succinate dehydrogenase activity+++GO:0008177///succinate dehydrogenase (ubiquinone) activity+++GO:0048039///ubiquinone binding+++GO:0009055///electron transfer activity+++GO:0016627///oxidoreductase activity, acting on the CH-CH group of donors+++GO:0046872///metal ion binding","GO:0006979///response to oxidative stress+++GO:0006121///mitochondrial electron transport, succinate to ubiquinone+++GO:0006099///tricarboxylic acid cycle+++GO:0022900///electron transport chain+++GO:0009060///aerobic respiration+++GO:0055114///oxidation-reduction process","IPR000701///Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit+++IPR018495///Succinate dehydrogenase, cytochrome b subunit, conserved site+++IPR014314///Succinate dehydrogenase, cytochrome b556 subunit+++IPR034804///Fumarate reductase/succinate dehydrogenase, transmembrane subunit","[C560_HUMAN|Reviewed]RecName: Full=Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; AltName: Full=Integral membrane protein CII-3; AltName: Full=QPs-1; Short=QPs1; AltName: Full=Succinate dehydrogenase complex subunit C; AltName: Full=Succinate-ubiquinone oxidoreductase cytochrome B large subunit; Short=CYBL; Flags: Precursor;+++[A0A087WZU7_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase cytochrome b560 subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000482902}; Flags: Fragment;+++[A0A0S2Z4B0_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase complex subunit C integral membrane protein 15kDa isoform 4 {ECO:0000313|EMBL:ALQ33782.1}; Flags: Fragment;+++[A0A0S2Z4B6_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase complex subunit C integral membrane protein 15kDa isoform 3 {ECO:0000313|EMBL:ALQ33781.1}; Flags: Fragment;+++[A0A0S2Z4B7_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase complex subunit C integral membrane protein 15kDa isoform 1 {ECO:0000313|EMBL:ALQ33779.1}; Flags: Fragment;+++[A0A0S2Z4C9_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase complex subunit C integral membrane protein 15kDa isoform 2 {ECO:0000313|EMBL:ALQ33780.1}; Flags: Fragment;+++[D3DVH1_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa, isoform CRA_a {ECO:0000313|EMBL:EAW52598.1};+++[D6RBX6_HUMAN|Unreviewed]SubName: Full=Succinate dehydrogenase cytochrome b560 subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000423929};+++[Q6IAQ2_HUMAN|Unreviewed]SubName: Full=SDHC protein {ECO:0000313|EMBL:CAG33383.1};"]
[63932,"'CXorf56'",157,117.99,137.495,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0044297///cell body+++GO:0005634///nucleus",null,null,"IPR029704///UPF0428 family","[CX056_HUMAN|Reviewed]RecName: Full=UPF0428 protein CXorf56;"]
[63947,"'DMRTC1'",0,1,0.5,{"$nulls":4},"GO:0005634///nucleus","GO:0042803///protein homodimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR026607///DMRT/protein doublesex/protein male abnormal 3+++IPR031577///Doublesex- and mab-3-related transcription factor C1/C2, C-terminal","[DMRTC_HUMAN|Reviewed]RecName: Full=Doublesex- and mab-3-related transcription factor C1;+++[A0A024R4F7_HUMAN|Unreviewed]SubName: Full=HCG1731871, isoform CRA_b {ECO:0000313|EMBL:EAW71831.1};+++[A0A087X258_HUMAN|Unreviewed]SubName: Full=Doublesex- and mab-3-related transcription factor C1 {ECO:0000313|Ensembl:ENSP00000484718}; Flags: Fragment;+++[A6QRF2_HUMAN|Unreviewed]SubName: Full=DMRT-like family C1 {ECO:0000313|EMBL:CAO72055.1}; Flags: Fragment;+++[G3V190_HUMAN|Unreviewed]SubName: Full=Doublesex- and mab-3-related transcription factor C1 {ECO:0000313|Ensembl:ENSP00000435159}; SubName: Full=HCG1731871, isoform CRA_c {ECO:0000313|EMBL:EAW71832.1};"]
[64064,"'OXCT2'",7,3,5,"00072///Synthesis and degradation of ketone bodies+++00280///Valine, leucine and isoleucine degradation+++00650///Butanoate metabolism","H01121///Succinyl CoA:3-oxoacid CoA transferase (SCOT) deficiency",null,"R00410///succinyl-CoA:acetoacetate CoA-transferase   Succinyl-CoA + Acetoacetate <=> Succinate + Acetoacetyl-CoA","GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion+++GO:0031514///motile cilium","GO:0016740///transferase activity+++GO:0008260///3-oxoacid CoA-transferase activity+++GO:0008410///CoA-transferase activity","GO:0046952///ketone body catabolic process","IPR012792///3-oxoacid CoA-transferase, subunit A+++IPR004163///Coenzyme A transferase binding site+++IPR012791///3-oxoacid CoA-transferase, subunit B+++IPR004164///Coenzyme A transferase active site+++IPR037171///NagB/RpiA transferase-like+++IPR004165///Coenzyme A transferase family I+++IPR014388///3-oxoacid CoA-transferase","[SCOT2_HUMAN|Reviewed]RecName: Full=Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial; EC=2.8.3.5; AltName: Full=3-oxoacid CoA-transferase 2A; AltName: Full=Testis-specific succinyl-CoA:3-oxoacid CoA-transferase; Short=SCOT-t; Flags: Precursor;+++[Q6INA3_HUMAN|Unreviewed]SubName: Full=OXCT2 protein {ECO:0000313|EMBL:AAH72388.1};"]
[64093,"'SMOC1'",25,26,25.5,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0005576///extracellular region+++GO:0005604///basement membrane","GO:0050840///extracellular matrix binding+++GO:0005509///calcium ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0060173///limb development+++GO:0007275///multicellular organism development+++GO:0001654///eye development+++GO:0030154///cell differentiation+++GO:0045667///regulation of osteoblast differentiation","IPR036857///Thyroglobulin type-1 superfamily+++IPR037639///SMOC-1, extracellular calcium-binding domain+++IPR036058///Kazal domain superfamily+++IPR018247///EF-Hand 1, calcium-binding site+++IPR000716///Thyroglobulin type-1+++IPR002350///Kazal domain+++IPR019577///SPARC/Testican, calcium-binding domain+++IPR011992///EF-hand domain pair","[SMOC1_HUMAN|Reviewed]RecName: Full=SPARC-related modular calcium-binding protein 1; AltName: Full=Secreted modular calcium-binding protein 1; Short=SMOC-1; Flags: Precursor;+++[A0A024R6E0_HUMAN|Unreviewed]SubName: Full=SPARC related modular calcium binding 1, isoform CRA_b {ECO:0000313|EMBL:EAW81015.1};"]
[64122,"'FN3K'",515,363,439,{"$nulls":4},"GO:0005829///cytosol+++GO:0005575///cellular_component","GO:0016740///transferase activity+++GO:0030387///fructosamine-3-kinase activity+++GO:0016301///kinase activity","GO:0030393///fructoselysine metabolic process+++GO:0016310///phosphorylation+++GO:0043687///post-translational protein modification+++GO:0030389///fructosamine metabolic process+++GO:0030855///epithelial cell differentiation","IPR016477///Fructosamine/Ketosamine-3-kinase+++IPR011009///Protein kinase-like domain superfamily","[FN3K_HUMAN|Reviewed]RecName: Full=Fructosamine-3-kinase; EC=2.7.1.-;"]
[64147,"'KIF9'",73,51,62,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0002102///podosome+++GO:0005737///cytoplasm+++GO:0005874///microtubule+++GO:0005856///cytoskeleton+++GO:0031982///vesicle+++GO:0005871///kinesin complex","GO:0008017///microtubule binding+++GO:0005515///protein binding+++GO:0003777///microtubule motor activity+++GO:0000166///nucleotide binding+++GO:0016887///ATPase activity+++GO:0003774///motor activity+++GO:0005524///ATP binding+++GO:0046983///protein dimerization activity","GO:0022617///extracellular matrix disassembly+++GO:1903008///organelle disassembly+++GO:0071801///regulation of podosome assembly+++GO:0007018///microtubule-based movement","IPR001752///Kinesin motor domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR027640///Kinesin-like protein+++IPR019821///Kinesin motor domain, conserved site+++IPR036961///Kinesin motor domain superfamily","[KIF9_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF9;+++[A0A024R2R8_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[A8K932_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[B4DZK5_HUMAN|Unreviewed]RecName: Full=Kinesin-like protein {ECO:0000256|RuleBase:RU000394};+++[C9JWZ7_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF9 {ECO:0000313|Ensembl:ENSP00000387959}; Flags: Fragment;+++[E7EUW8_HUMAN|Unreviewed]SubName: Full=Kinesin-like protein KIF9 {ECO:0000313|Ensembl:ENSP00000406603};+++[Q6PJI1_HUMAN|Unreviewed]SubName: Full=KIF9 protein {ECO:0000313|EMBL:AAH15311.1}; SubName: Full=Kinesin-like protein KIF9 {ECO:0000313|Ensembl:ENSP00000391099};"]
[64149,"'C17orf75'",95.98,105.91,100.945,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0005802///trans-Golgi network+++GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0006886///intracellular protein transport+++GO:0099041///vesicle tethering to Golgi","IPR028280///Protein Njmu-R1","[NJMU_HUMAN|Reviewed]RecName: Full=Protein Njmu-R1;+++[J3KRR1_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000462127}; Flags: Fragment;+++[J3KT97_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000462873}; Flags: Fragment;+++[J3QKQ1_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000463184};+++[J3QRW7_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000464416}; Flags: Fragment;+++[J9JIC5_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000225805};+++[K7EII1_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000464759}; Flags: Fragment;+++[K7EIQ2_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000464845}; Flags: Fragment;+++[K7ERX0_HUMAN|Unreviewed]SubName: Full=Protein Njmu-R1 {ECO:0000313|Ensembl:ENSP00000468451}; Flags: Fragment;"]
[64207,"'IRF2BPL'",2566,2271,2418.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005615///extracellular space","GO:0003674///molecular_function+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0046543///development of secondary female sexual characteristics","IPR022750///Interferon regulatory factor 2-binding protein 1 & 2, zinc finger","[I2BPL_HUMAN|Reviewed]RecName: Full=Interferon regulatory factor 2-binding protein-like; AltName: Full=Enhanced at puberty protein 1;"]
[64225,"'ATL2'",147,122,134.5,null,"H00266///Hereditary spastic paraplegia (SPG)+++H00265///Hereditary sensory and autonomic neuropathy (HSAN)",null,null,"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0098826///endoplasmic reticulum tubular network membrane+++GO:0016021///integral component of membrane","GO:0005525///GTP binding+++GO:0000166///nucleotide binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0003924///GTPase activity+++GO:0016787///hydrolase activity","GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0007029///endoplasmic reticulum organization+++GO:0051260///protein homooligomerization+++GO:0007030///Golgi organization+++GO:1990809///endoplasmic reticulum tubular network membrane organization","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR036543///Guanylate-binding protein, C-terminal domain superfamily+++IPR003191///Guanylate-binding protein/Atlastin, C-terminal+++IPR015894///Guanylate-binding protein, N-terminal+++IPR030386///GB1/RHD3-type guanine nucleotide-binding (G) domain","[ATLA2_HUMAN|Reviewed]RecName: Full=Atlastin-2; EC=3.6.5.-; AltName: Full=ADP-ribosylation factor-like protein 6-interacting protein 2; Short=ARL-6-interacting protein 2; Short=Aip-2;+++[B5MCN0_HUMAN|Unreviewed]SubName: Full=Atlastin-2 {ECO:0000313|Ensembl:ENSP00000385446};+++[B7Z2H0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57300, highly similar to Homo sapiens ADP-ribosylation factor-like 6 interacting protein 2 (ARL6IP2), mRNA {ECO:0000313|EMBL:BAH11856.1};+++[C9JC25_HUMAN|Unreviewed]SubName: Full=Atlastin-2 {ECO:0000313|Ensembl:ENSP00000404921}; Flags: Fragment;+++[C9JQQ5_HUMAN|Unreviewed]SubName: Full=Atlastin-2 {ECO:0000313|Ensembl:ENSP00000409811}; Flags: Fragment;+++[F8WBH0_HUMAN|Unreviewed]SubName: Full=Atlastin-2 {ECO:0000313|Ensembl:ENSP00000406004};+++[F8WD17_HUMAN|Unreviewed]SubName: Full=Atlastin-2 {ECO:0000313|Ensembl:ENSP00000383944};+++[F8WEN4_HUMAN|Unreviewed]SubName: Full=Atlastin-2 {ECO:0000313|Ensembl:ENSP00000413216};+++[H7C3A2_HUMAN|Unreviewed]SubName: Full=Atlastin-2 {ECO:0000313|Ensembl:ENSP00000410592}; Flags: Fragment;"]
[6428,"'SRSF3'",708,700,704,"05168///Herpes simplex infection+++03040///Spliceosome",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:1990825///sequence-specific mRNA binding","GO:0045292///mRNA cis splicing, via spliceosome+++GO:0051028///mRNA transport+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus+++GO:0048024///regulation of mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","IPR000504///RNA recognition motif domain+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[SRSF3_HUMAN|Reviewed]RecName: Full=Serine/arginine-rich splicing factor 3; AltName: Full=Pre-mRNA-splicing factor SRP20; AltName: Full=Splicing factor, arginine/serine-rich 3;+++[A0A087X2D0_HUMAN|Unreviewed]SubName: Full=Serine/arginine-rich-splicing factor 3 {ECO:0000313|Ensembl:ENSP00000484891};+++[B2R6F3_HUMAN|Unreviewed]SubName: Full=Splicing factor arginine/serine-rich 3 {ECO:0000313|EMBL:BAG70043.1}; SubName: Full=Splicing factor, arginine/serine-rich 3, isoform CRA_d {ECO:0000313|EMBL:EAX03901.1}; SubName: Full=cDNA, FLJ92926, Homo sapiens splicing factor, arginine/serine-rich 3 (SFRS3), mRNA {ECO:0000313|EMBL:BAG35450.1};"]
[643155,"'SMIM15'",409,361,385,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IPR027877///Small integral membrane protein 15","[SIM15_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 15;"]
[643338,"'C15orf62'",0,1,0.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005739///mitochondrion","GO:0017049///GTP-Rho binding","GO:0007266///Rho protein signal transduction+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0008360///regulation of cell shape+++GO:0030838///positive regulation of actin filament polymerization","IPR034254///DNAJC17, RNA recognition motif+++IPR000504///RNA recognition motif domain+++IPR036869///Chaperone J-domain superfamily+++IPR001623///DnaJ domain+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[CO062_HUMAN|Reviewed]RecName: Full=Uncharacterized protein C15orf62, mitochondrial; Flags: Precursor;"]
[643707,"'GOLGA6L4'",61.78,75.31,68.545,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus","GO:0008022///protein C-terminus binding+++GO:0008017///microtubule binding+++GO:0042802///identical protein binding+++GO:0031749///D2 dopamine receptor binding+++GO:0005525///GTP binding+++GO:0050998///nitric-oxide synthase binding+++GO:0003924///GTPase activity+++GO:0019901///protein kinase binding+++GO:0017124///SH3 domain binding+++GO:0046983///protein dimerization activity+++GO:0044877///protein-containing complex binding","GO:0016185///synaptic vesicle budding from presynaptic endocytic zone membrane+++GO:0051262///protein tetramerization+++GO:0002031///G protein-coupled receptor internalization+++GO:0007605///sensory perception of sound+++GO:0051932///synaptic transmission, GABAergic+++GO:0031623///receptor internalization+++GO:0072583///clathrin-dependent endocytosis+++GO:1901998///toxin transport+++GO:0050804///modulation of chemical synaptic transmission+++GO:0007032///endosome organization+++GO:1903423///positive regulation of synaptic vesicle recycling+++GO:0061025///membrane fusion+++GO:1900242///regulation of synaptic vesicle endocytosis+++GO:0008344///adult locomotory behavior+++GO:0006898///receptor-mediated endocytosis+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:1904645///response to amyloid-beta+++GO:0000266///mitochondrial fission","IPR024858///Golgin subfamily A+++IPR026737///Golgin subfamily A member 6-like","[GG6L4_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 6-like protein 4;+++[H0YA86_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 4 {ECO:0000313|Ensembl:ENSP00000426395}; Flags: Fragment;+++[J3KQ80_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 4 {ECO:0000313|Ensembl:ENSP00000389305};"]
[64397,"'ZNF106'",1286.02,2117.01,1701.515,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0017124///SH3 domain binding","GO:0008286///insulin receptor signaling pathway","IPR036322///WD40-repeat-containing domain superfamily+++IPR001680///WD40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR017986///WD40-repeat-containing domain","[ZN106_HUMAN|Reviewed]RecName: Full=Zinc finger protein 106; Short=Zfp-106; AltName: Full=Zinc finger protein 474;+++[A0A024R9R5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW92554.1};+++[A0A0C4DGM5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 homolog (Mouse), isoform CRA_c {ECO:0000313|EMBL:EAW92553.1};+++[H3BNJ4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 {ECO:0000313|Ensembl:ENSP00000454882}; Flags: Fragment;+++[H3BNX5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 {ECO:0000313|Ensembl:ENSP00000455049}; Flags: Fragment;+++[H3BRD4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 {ECO:0000313|Ensembl:ENSP00000456191}; Flags: Fragment;+++[H3BS99_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 {ECO:0000313|Ensembl:ENSP00000456604}; Flags: Fragment;+++[H3BSS6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 {ECO:0000313|Ensembl:ENSP00000456845}; Flags: Fragment;+++[L8EB46_HUMAN|Unreviewed]SubName: Full=Alternative protein ZFP106 {ECO:0000313|EMBL:CCQ43688.1};+++[Q05C49_HUMAN|Unreviewed]SubName: Full=ZFP106 protein {ECO:0000313|EMBL:AAH29366.1}; Flags: Fragment;+++[Q0VGA6_HUMAN|Unreviewed]SubName: Full=ZFP106 protein {ECO:0000313|EMBL:AAI11397.1}; Flags: Fragment;+++[U3KQH7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 106 {ECO:0000313|Ensembl:ENSP00000475881}; Flags: Fragment;"]
[64417,"'TMEM267'",98.03,108.01,103.02,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity","GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated","IPR026572///Transmembrane protein 267","[TM267_HUMAN|Reviewed]RecName: Full=Transmembrane protein 267 {ECO:0000312|HGNC:HGNC:26139};+++[A0A024R0B8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW56064.1};+++[D6RAV6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 267 {ECO:0000313|Ensembl:ENSP00000424720}; Flags: Fragment;+++[E9PBX6_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 267 {ECO:0000313|Ensembl:ENSP00000427099};+++[Q6GMT5_HUMAN|Unreviewed]SubName: Full=C5orf28 protein {ECO:0000313|EMBL:AAH73852.1};"]
[64430,"'PCNX4'",546,560,553,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0030054///cell junction+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0030018///Z disc+++GO:0005634///nucleus","GO:0016791///phosphatase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0042132///fructose 1,6-bisphosphate 1-phosphatase activity+++GO:0042578///phosphoric ester hydrolase activity+++GO:0016787///hydrolase activity+++GO:0003824///catalytic activity","GO:0008152///metabolic process+++GO:0005986///sucrose biosynthetic process+++GO:0006000///fructose metabolic process+++GO:0030388///fructose 1,6-bisphosphate metabolic process+++GO:0016311///dephosphorylation+++GO:0005975///carbohydrate metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:0006094///gluconeogenesis","IPR039797///Protein Pecanex+++IPR007735///Pecanex, C-terminal","[PCX4_HUMAN|Reviewed]RecName: Full=Pecanex-like protein 4; AltName: Full=Hepatitis C virus F protein-binding protein 2; Short=HCV F protein-binding protein 2; AltName: Full=Pecanex homolog protein 4 {ECO:0000312|HGNC:HGNC:20349};+++[B5MC47_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 4 {ECO:0000313|Ensembl:ENSP00000385201};+++[B6ZDM2_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 4 {ECO:0000313|Ensembl:ENSP00000317396};+++[H0YIY3_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 4 {ECO:0000313|Ensembl:ENSP00000450441}; Flags: Fragment;+++[H0YJ84_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 4 {ECO:0000313|Ensembl:ENSP00000450994}; Flags: Fragment;+++[H0YJN3_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 4 {ECO:0000313|Ensembl:ENSP00000451836}; Flags: Fragment;+++[H0YJV9_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 4 {ECO:0000313|Ensembl:ENSP00000452234}; Flags: Fragment;+++[H9KV87_HUMAN|Unreviewed]SubName: Full=Pecanex-like protein 4 {ECO:0000313|Ensembl:ENSP00000375469};+++[Q9UJ73_HUMAN|Unreviewed]SubName: Full=Fructose-1,6-bisphosphatase {ECO:0000313|EMBL:CAB58561.1}; EC=3.1.3.11 {ECO:0000313|EMBL:CAB58561.1}; Flags: Fragment;+++[Q9UMQ9_HUMAN|Unreviewed]SubName: Full=Fructose-1,6-bisphosphatase {ECO:0000313|EMBL:CAB53366.1}; EC=3.1.3.11 {ECO:0000313|EMBL:CAB53366.1}; Flags: Fragment;+++[Q9UMR0_HUMAN|Unreviewed]SubName: Full=Fructose-1,6-bisphosphatase {ECO:0000313|EMBL:CAB53359.1}; EC=3.1.3.11 {ECO:0000313|EMBL:CAB53359.1}; Flags: Fragment;"]
[644815,"'FAM83G'",655,647,651,{"$nulls":4},"GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0030509///BMP signaling pathway","IPR012461///FAM83","[FA83G_HUMAN|Reviewed]RecName: Full=Protein FAM83G; AltName: Full=Protein associated with SMAD1 {ECO:0000303|PubMed:24554596};+++[K7EKG0_HUMAN|Unreviewed]SubName: Full=Protein FAM83G {ECO:0000313|Ensembl:ENSP00000465602}; Flags: Fragment;"]
[6455,"'SH3GL1'",5138,5014,5076,"04144///Endocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0099092///postsynaptic density, intracellular component+++GO:0002102///podosome+++GO:0098793///presynapse+++GO:0042995///cell projection+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0098686///hippocampal mossy fiber to CA3 synapse+++GO:0030054///cell junction+++GO:0005768///endosome+++GO:0031901///early endosome membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0098978///glutamatergic synapse+++GO:0045202///synapse","GO:0008022///protein C-terminus binding+++GO:0008289///lipid binding+++GO:0051020///GTPase binding+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0017124///SH3 domain binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0044325///ion channel binding+++GO:0045296///cadherin binding+++GO:0019902///phosphatase binding","GO:0007417///central nervous system development+++GO:0006897///endocytosis+++GO:0098815///modulation of excitatory postsynaptic potential+++GO:0007165///signal transduction+++GO:1900244///positive regulation of synaptic vesicle endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:1900242///regulation of synaptic vesicle endocytosis","IPR004148///BAR domain+++IPR027267///AH/BAR domain superfamily+++IPR028501///Endophilin-A+++IPR035824///Endophilin-A, SH3 domain+++IPR001452///SH3 domain+++IPR036028///SH3-like domain superfamily","[SH3G1_HUMAN|Reviewed]RecName: Full=Endophilin-A2; AltName: Full=EEN fusion partner of MLL; AltName: Full=Endophilin-2; AltName: Full=Extra eleven-nineteen leukemia fusion gene protein; Short=EEN; AltName: Full=SH3 domain protein 2B; AltName: Full=SH3 domain-containing GRB2-like protein 1;+++[M0QYE0_HUMAN|Unreviewed]SubName: Full=Endophilin-A2 {ECO:0000313|Ensembl:ENSP00000469766}; Flags: Fragment;+++[M0R0I3_HUMAN|Unreviewed]SubName: Full=Endophilin-A2 {ECO:0000313|Ensembl:ENSP00000471260}; Flags: Fragment;+++[M0R2K6_HUMAN|Unreviewed]SubName: Full=Endophilin-A2 {ECO:0000313|Ensembl:ENSP00000472640}; Flags: Fragment;+++[Q6FGM0_HUMAN|Unreviewed]SubName: Full=SH3-domain GRB2-like 1 {ECO:0000313|EMBL:AAH98565.1, ECO:0000313|EMBL:AAQ76799.1}; SubName: Full=SH3-domain GRB2-like 1, isoform CRA_b {ECO:0000313|EMBL:EAW69228.1}; SubName: Full=SH3GL1 protein {ECO:0000313|EMBL:CAG46884.1}; SubName: Full=cDNA, FLJ96508, Homo sapiens SH3-domain GRB2-like 1 (SH3GL1), mRNA {ECO:0000313|EMBL:BAG37838.1};+++[Q9BVL7_HUMAN|Unreviewed]SubName: Full=SH3GL1 protein {ECO:0000313|EMBL:AAH01094.2}; Flags: Fragment;+++[Q9BWP4_HUMAN|Unreviewed]SubName: Full=SH3GL1 protein {ECO:0000313|EMBL:AAH00089.2}; Flags: Fragment;"]
[64651,"'CSRNP1'",394,491,442.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060325///face morphogenesis+++GO:0048008///platelet-derived growth factor receptor signaling pathway+++GO:0006915///apoptotic process+++GO:0060021///roof of mouth development+++GO:0009791///post-embryonic development+++GO:0048705///skeletal system morphogenesis+++GO:0006355///regulation of transcription, DNA-templated","IPR031972///Cysteine/serine-rich nuclear protein, N-terminal domain+++IPR023260///Cysteine/serine-rich nuclear protein family","[CSRN1_HUMAN|Reviewed]RecName: Full=Cysteine/serine-rich nuclear protein 1; Short=CSRNP-1; AltName: Full=Axin-1 up-regulated gene 1 protein; AltName: Full=Protein URAX1; AltName: Full=TGF-beta-induced apoptosis protein 3; Short=TAIP-3;+++[A0A024R2N7_HUMAN|Unreviewed]SubName: Full=AXIN1 up-regulated 1, isoform CRA_a {ECO:0000313|EMBL:EAW64568.1};+++[L8E921_HUMAN|Unreviewed]SubName: Full=Alternative protein CSRNP1 {ECO:0000313|EMBL:CCQ43790.1};"]
[647042,"'GOLGA6L10'",7.02,1.98,4.5,{"$nulls":4},"GO:0005794///Golgi apparatus",null,null,"IPR024858///Golgin subfamily A+++IPR026737///Golgin subfamily A member 6-like","[GG6LA_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000305};+++[A0A087X0T7_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000313|Ensembl:ENSP00000483647};+++[A0A087X1J3_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000313|Ensembl:ENSP00000484254};+++[A0A0G2JM30_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000313|Ensembl:ENSP00000478445};+++[A0A0G2JNH6_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000313|Ensembl:ENSP00000481389};+++[A0A0J9YW09_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000313|Ensembl:ENSP00000487759};+++[A0A0M3HER8_HUMAN|Unreviewed]SubName: Full=Golgin subfamily A member 6-like protein 10 {ECO:0000313|Ensembl:ENSP00000488730};"]
[64743,"'WDR13'",711,708,709.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005815///microtubule organizing center+++GO:0005886///plasma membrane+++GO:0005634///nucleus","GO:1990841///promoter-specific chromatin binding","GO:1904691///negative regulation of type B pancreatic cell proliferation","IPR017986///WD40-repeat-containing domain+++IPR001680///WD40 repeat+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[WDR13_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 13;+++[A0A087WWV5_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 13 {ECO:0000313|Ensembl:ENSP00000480532}; Flags: Fragment;+++[A0A087X091_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 13 {ECO:0000313|Ensembl:ENSP00000483191}; Flags: Fragment;+++[A0A087X2H9_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 13 {ECO:0000313|Ensembl:ENSP00000484996};+++[Q06DW9_HUMAN|Unreviewed]SubName: Full=WDR13 {ECO:0000313|EMBL:ABI93268.1};+++[Q14827_HUMAN|Unreviewed]SubName: Full=MG21 protein {ECO:0000313|EMBL:AAA74509.1}; Flags: Fragment;+++[Q6NXG4_HUMAN|Unreviewed]SubName: Full=WDR13 protein {ECO:0000313|EMBL:AAH67094.1}; Flags: Fragment;"]
[64762,"'GAREM1'",30,40,35,{"$nulls":4},"GO:0005886///plasma membrane","GO:0070064///proline-rich region binding+++GO:0005515///protein binding","GO:0051781///positive regulation of cell division+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0008284///positive regulation of cell proliferation","IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR025946///CABIT domain","[GARE1_HUMAN|Reviewed]RecName: Full=GRB2-associated and regulator of MAPK protein 1; AltName: Full=GRB2-associated and regulator of MAPK1;+++[J3QRF3_HUMAN|Unreviewed]SubName: Full=GRB2-associated and regulator of MAPK protein 1 {ECO:0000313|Ensembl:ENSP00000464185}; Flags: Fragment;"]
[6478,"'SIAH2'",662,826,744,{"$nulls":4},"GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0043005///neuron projection+++GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0008270///zinc ion binding+++GO:0003714///transcription corepressor activity+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0016740///transferase activity","GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0043066///negative regulation of apoptotic process+++GO:0044257///cellular protein catabolic process+++GO:0044267///cellular protein metabolic process+++GO:0006915///apoptotic process+++GO:0007264///small GTPase mediated signal transduction+++GO:0007049///cell cycle+++GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:1902842///negative regulation of netrin-activated signaling pathway+++GO:0007275///multicellular organism development+++GO:0016567///protein ubiquitination+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0000209///protein polyubiquitination+++GO:0042752///regulation of circadian rhythm+++GO:0031396///regulation of protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR008974///TRAF-like+++IPR001841///Zinc finger, RING-type+++IPR013010///Zinc finger, SIAH-type+++IPR018121///Seven-in-absentia protein, TRAF-like domain+++IPR004162///E3 ubiquitin-protein ligase SIN-like","[SIAH2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase SIAH2; EC=2.3.2.27; AltName: Full=RING-type E3 ubiquitin transferase SIAH2 {ECO:0000305}; AltName: Full=Seven in absentia homolog 2; Short=Siah-2; Short=hSiah2;+++[C9J9D7_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin-protein ligase {ECO:0000256|RuleBase:RU201113}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU201113}; Flags: Fragment;"]
[64798,"'DEPTOR'",17,22,19.5,"04140///Autophagy - animal+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005622///intracellular","GO:0005515///protein binding","GO:0045792///negative regulation of cell size+++GO:2001236///regulation of extrinsic apoptotic signaling pathway+++GO:0006469///negative regulation of protein kinase activity+++GO:0032007///negative regulation of TOR signaling+++GO:0035556///intracellular signal transduction","IPR037589///DEP domain-containing mTOR-interacting protein+++IPR037335///DEP domain-containing mTOR-interacting protein, DEP domain 1+++IPR036034///PDZ superfamily+++IPR037336///DEP domain-containing mTOR-interacting protein, DEP domain 2+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR001478///PDZ domain+++IPR000591///DEP domain+++IPR036390///Winged helix DNA-binding domain superfamily","[DPTOR_HUMAN|Reviewed]RecName: Full=DEP domain-containing mTOR-interacting protein; AltName: Full=DEP domain-containing protein 6;"]
[64843,"'ISL2'",8,9,8.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0021524///visceral motor neuron differentiation+++GO:0048935///peripheral nervous system neuron development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0021520///spinal cord motor neuron cell fate specification+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0045665///negative regulation of neuron differentiation+++GO:0031290///retinal ganglion cell axon guidance+++GO:0048666///neuron development+++GO:0048663///neuron fate commitment","IPR001781///Zinc finger, LIM-type+++IPR009057///Homeobox-like domain superfamily+++IPR001356///Homeobox domain+++IPR017970///Homeobox, conserved site","[ISL2_HUMAN|Reviewed]RecName: Full=Insulin gene enhancer protein ISL-2; Short=Islet-2;+++[F1T0J9_HUMAN|Unreviewed]SubName: Full=Insulin gene enhancer protein ISL-2 {ECO:0000313|EMBL:BAJ84073.1};+++[H0YN25_HUMAN|Unreviewed]SubName: Full=Insulin gene enhancer protein ISL-2 {ECO:0000313|Ensembl:ENSP00000453837};"]
[64863,"'METTL4'",38,47,42.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0009007///site-specific DNA-methyltransferase (adenine-specific) activity+++GO:0008168///methyltransferase activity","GO:0032775///DNA methylation on adenine+++GO:0032259///methylation","IPR029063///S-adenosyl-L-methionine-dependent methyltransferase+++IPR007757///MT-A70-like+++IPR002052///DNA methylase, N-6 adenine-specific, conserved site","[METL4_HUMAN|Reviewed]RecName: Full=Methyltransferase-like protein 4; EC=2.1.1.-;+++[I3L0Y1_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000458415}; Flags: Fragment;+++[I3L3W2_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000460774}; Flags: Fragment;+++[I3L4A0_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000461097}; Flags: Fragment;+++[I6L9E3_HUMAN|Unreviewed]SubName: Full=METTL4 protein {ECO:0000313|EMBL:AAH56270.2}; Flags: Fragment;+++[J3KNJ7_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000320349};+++[L8EB52_HUMAN|Unreviewed]SubName: Full=Alternative protein METTL4 {ECO:0000313|EMBL:CCQ43698.1};+++[V9GYU3_HUMAN|Unreviewed]SubName: Full=Methyltransferase-like protein 4 {ECO:0000313|Ensembl:ENSP00000477089}; Flags: Fragment;"]
[6492,"'SIM1'",0,1,0.5,null,"H02106///Genetic obesity",null,null,"GO:0005634///nucleus","GO:0046982///protein heterodimerization activity+++GO:0046983///protein dimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001657///ureteric bud development+++GO:0007399///nervous system development+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development","IPR013655///PAS fold-3+++IPR001610///PAC motif+++IPR035965///PAS domain superfamily+++IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR010578///Single-minded, C-terminal+++IPR000014///PAS domain+++IPR013767///PAS fold+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain","[SIM1_HUMAN|Reviewed]RecName: Full=Single-minded homolog 1; AltName: Full=Class E basic helix-loop-helix protein 14; Short=bHLHe14;+++[L0R542_HUMAN|Unreviewed]SubName: Full=Alternative protein SIM1 {ECO:0000313|EMBL:CCO13813.1};"]
[6496,"'SIX3'",1318,1242,1280,null,"H01160///Schizencephaly+++H01027///Anophthalmia and microphthalmia (A/M)+++H00267///Holoprosencephaly (HPE)",null,null,"GO:0005667///transcription factor complex+++GO:0005634///nucleus","GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0043565///sequence-specific DNA binding+++GO:0003713///transcription coactivator activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005102///signaling receptor binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0042826///histone deacetylase binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0021798///forebrain dorsal/ventral pattern formation+++GO:0021797///forebrain anterior/posterior pattern specification+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0021536///diencephalon development+++GO:0060235///lens induction in camera-type eye+++GO:0043010///camera-type eye development+++GO:0021537///telencephalon development+++GO:0042127///regulation of cell proliferation+++GO:1990086///lens fiber cell apoptotic process+++GO:0048856///anatomical structure development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007420///brain development+++GO:0003404///optic vesicle morphogenesis+++GO:0045665///negative regulation of neuron differentiation+++GO:0007601///visual perception+++GO:0021978///telencephalon regionalization+++GO:0002070///epithelial cell maturation+++GO:1901987///regulation of cell cycle phase transition+++GO:0014016///neuroblast differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0021983///pituitary gland development+++GO:0007275///multicellular organism development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0000060///protein import into nucleus, translocation+++GO:0002088///lens development in camera-type eye+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:1902742///apoptotic process involved in development+++GO:1902692///regulation of neuroblast proliferation+++GO:2000177///regulation of neural precursor cell proliferation+++GO:0006606///protein import into nucleus+++GO:0048512///circadian behavior+++GO:0061074///regulation of neural retina development+++GO:0009946///proximal/distal axis specification+++GO:0021846///cell proliferation in forebrain+++GO:0097402///neuroblast migration+++GO:0001654///eye development+++GO:0070306///lens fiber cell differentiation","IPR032949///Homeobox protein SIX3+++IPR009057///Homeobox-like domain superfamily+++IPR000047///Helix-turn-helix motif+++IPR001356///Homeobox domain+++IPR031701///Homeobox protein SIX1, N-terminal SD domain","[SIX3_HUMAN|Reviewed]RecName: Full=Homeobox protein SIX3; AltName: Full=Sine oculis homeobox homolog 3;+++[A0A0D3RS46_HUMAN|Unreviewed]SubName: Full=SIX homeobox 3 {ECO:0000313|EMBL:AJS11514.1}; Flags: Fragment;+++[A0A127AXB2_HUMAN|Unreviewed]SubName: Full=Sine oculis homeobox-like protein 3 {ECO:0000313|EMBL:AMM45336.1}; Flags: Fragment;+++[A0A127AXF1_HUMAN|Unreviewed]SubName: Full=Sine oculis homeobox-like protein 3 {ECO:0000313|EMBL:AMM45337.1}; Flags: Fragment;+++[A0A1Y0ZN85_HUMAN|Unreviewed]SubName: Full=Homeobox protein SIX3 {ECO:0000313|EMBL:BAV00951.1}; Flags: Fragment;+++[A0A1Y0ZVZ1_HUMAN|Unreviewed]SubName: Full=Homeobox protein SIX3 {ECO:0000313|EMBL:BAV00948.1}; Flags: Fragment;+++[A0PJI2_HUMAN|Unreviewed]SubName: Full=SIX3 protein {ECO:0000313|EMBL:AAH30289.1}; Flags: Fragment;"]
[650,"'BMP2'",221,216,218.5,"04350///TGF-beta signaling pathway+++04060///Cytokine-cytokine receptor interaction+++05200///Pathways in cancer+++04390///Hippo signaling pathway+++05217///Basal cell carcinoma","H00482///Brachydactyly","M00679///BMP signaling",null,"GO:0009986///cell surface+++GO:0070724///BMP receptor complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0004745///retinol dehydrogenase activity+++GO:0070700///BMP receptor binding+++GO:0046332///SMAD binding+++GO:0008083///growth factor activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0019211///phosphatase activator activity+++GO:0039706///co-receptor binding","GO:0007507///heart development+++GO:0071773///cellular response to BMP stimulus+++GO:0048711///positive regulation of astrocyte differentiation+++GO:0043408///regulation of MAPK cascade+++GO:0060485///mesenchyme development+++GO:0001666///response to hypoxia+++GO:0001934///positive regulation of protein phosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0045600///positive regulation of fat cell differentiation+++GO:0001837///epithelial to mesenchymal transition+++GO:0055114///oxidation-reduction process+++GO:0002062///chondrocyte differentiation+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:0042487///regulation of odontogenesis of dentin-containing tooth+++GO:0010922///positive regulation of phosphatase activity+++GO:0009887///animal organ morphogenesis+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0001649///osteoblast differentiation+++GO:0007275///multicellular organism development+++GO:1901522///positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus+++GO:0060128///corticotropin hormone secreting cell differentiation+++GO:0031648///protein destabilization+++GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0043410///positive regulation of MAPK cascade+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0060804///positive regulation of Wnt signaling pathway by BMP signaling pathway+++GO:0006468///protein phosphorylation+++GO:0003308///negative regulation of Wnt signaling pathway involved in heart development+++GO:0045165///cell fate commitment+++GO:0009617///response to bacterium+++GO:0061036///positive regulation of cartilage development+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0035054///embryonic heart tube anterior/posterior pattern specification+++GO:0071363///cellular response to growth factor stimulus+++GO:0021537///telencephalon development+++GO:0035051///cardiocyte differentiation+++GO:0033690///positive regulation of osteoblast proliferation+++GO:0010894///negative regulation of steroid biosynthetic process+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0043569///negative regulation of insulin-like growth factor receptor signaling pathway+++GO:0060129///thyroid-stimulating hormone-secreting cell differentiation+++GO:0030501///positive regulation of bone mineralization+++GO:0045778///positive regulation of ossification+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0030509///BMP signaling pathway+++GO:0045597///positive regulation of cell differentiation+++GO:0003181///atrioventricular valve morphogenesis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006029///proteoglycan metabolic process+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0000187///activation of MAPK activity+++GO:0001501///skeletal system development+++GO:0032348///negative regulation of aldosterone biosynthetic process+++GO:0048468///cell development+++GO:2000726///negative regulation of cardiac muscle cell differentiation+++GO:0048839///inner ear development+++GO:0072138///mesenchymal cell proliferation involved in ureteric bud development+++GO:0007267///cell-cell signaling+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0071407///cellular response to organic cyclic compound+++GO:0060039///pericardium development+++GO:0003130///BMP signaling pathway involved in heart induction+++GO:0030335///positive regulation of cell migration+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0045666///positive regulation of neuron differentiation+++GO:0007219///Notch signaling pathway+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0030154///cell differentiation+++GO:0030282///bone mineralization+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0051216///cartilage development+++GO:0035630///bone mineralization involved in bone maturation+++GO:0032092///positive regulation of protein binding+++GO:0045786///negative regulation of cell cycle+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0048762///mesenchymal cell differentiation+++GO:0001503///ossification+++GO:0010629///negative regulation of gene expression+++GO:0006355///regulation of transcription, DNA-templated+++GO:0003203///endocardial cushion morphogenesis+++GO:0055007///cardiac muscle cell differentiation+++GO:0021978///telencephalon regionalization+++GO:0010469///regulation of signaling receptor activity+++GO:0001701///in utero embryonic development+++GO:0006954///inflammatory response+++GO:0010628///positive regulation of gene expression+++GO:0042482///positive regulation of odontogenesis+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0008285///negative regulation of cell proliferation+++GO:2000065///negative regulation of cortisol biosynthetic process+++GO:0051042///negative regulation of calcium-independent cell-cell adhesion+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060395///SMAD protein signal transduction","IPR001839///Transforming growth factor-beta, C-terminal+++IPR017948///Transforming growth factor beta, conserved site+++IPR001111///TGF-beta, propeptide+++IPR029034///Cystine-knot cytokine+++IPR015615///Transforming growth factor-beta-related","[BMP2_HUMAN|Reviewed]RecName: Full=Bone morphogenetic protein 2; Short=BMP-2; AltName: Full=Bone morphogenetic protein 2A; Short=BMP-2A; Flags: Precursor;+++[C8C060_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32585.1};+++[C8C061_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX10387.1};+++[C8C063_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32588.1};+++[C8C064_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32589.1};+++[C8C065_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32590.1}; Flags: Fragment;+++[C8C066_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32591.1};+++[C8C068_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32593.1};+++[C8C069_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32594.1}; Flags: Fragment;+++[C8C071_HUMAN|Unreviewed]SubName: Full=Bone morphogenetic protein 2 {ECO:0000313|EMBL:ACV32596.1};+++[U3N491_HUMAN|Unreviewed]SubName: Full=BMP2 protein {ECO:0000313|EMBL:AGW22219.1}; Flags: Fragment;"]
[65061,"'CDK15'",9,6,7.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0004674///protein serine/threonine kinase activity+++GO:0016301///kinase activity+++GO:0030332///cyclin binding+++GO:0005515///protein binding+++GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding","GO:0016310///phosphorylation+++GO:0051726///regulation of cell cycle+++GO:0006468///protein phosphorylation","IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily","[CDK15_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 15; EC=2.7.11.22 {ECO:0000269|PubMed:24866247}; AltName: Full=Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein; AltName: Full=Cell division protein kinase 15; AltName: Full=Serine/threonine-protein kinase ALS2CR7; AltName: Full=Serine/threonine-protein kinase PFTAIRE-2;+++[F8WDP7_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 15 {ECO:0000313|Ensembl:ENSP00000389831};"]
[65108,"'MARCKSL1'",4198,3494,3846,"04666///Fc gamma R-mediated phagocytosis+++05140///Leishmaniasis",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0003779///actin binding+++GO:0005516///calmodulin binding","GO:0008284///positive regulation of cell proliferation","IPR002101///Myristoylated alanine-rich C-kinase substrate MARCKS","[MRP_HUMAN|Reviewed]RecName: Full=MARCKS-related protein; AltName: Full=MARCKS-like protein 1; AltName: Full=Macrophage myristoylated alanine-rich C kinase substrate; Short=Mac-MARCKS; Short=MacMARCKS;"]
[6520,"'SLC3A2'",3010,2774,2892,"04216///Ferroptosis+++04974///Protein digestion and absorption+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0016324///apical plasma membrane+++GO:0070062///extracellular exosome+++GO:0045202///synapse+++GO:0005634///nucleus+++GO:0042470///melanosome+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0045296///cadherin binding+++GO:0005432///calcium:sodium antiporter activity+++GO:0015175///neutral amino acid transmembrane transporter activity+++GO:0003725///double-stranded RNA binding+++GO:0003824///catalytic activity+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0015827///tryptophan transport+++GO:1903801///L-leucine import across plasma membrane+++GO:0050900///leukocyte migration+++GO:0006865///amino acid transport+++GO:0035725///sodium ion transmembrane transport+++GO:0043330///response to exogenous dsRNA+++GO:0005975///carbohydrate metabolic process+++GO:0006816///calcium ion transport","IPR017853///Glycoside hydrolase superfamily+++IPR031984///Solute carrier family 3 member 2, N-terminal domain+++IPR013780///Glycosyl hydrolase, all-beta+++IPR006047///Glycosyl hydrolase, family 13, catalytic domain","[4F2_HUMAN|Reviewed]RecName: Full=4F2 cell-surface antigen heavy chain; Short=4F2hc; AltName: Full=4F2 heavy chain antigen; AltName: Full=Lymphocyte activation antigen 4F2 large subunit; AltName: Full=Solute carrier family 3 member 2; AltName: CD_antigen=CD98;+++[A0A024R599_HUMAN|Unreviewed]SubName: Full=Solute carrier family 3 (Activators of dibasic and neutral amino acid transport), member 2, isoform CRA_e {ECO:0000313|EMBL:EAW74123.1};+++[F5GZI0_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000444439};+++[F5GZR9_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000444250}; Flags: Fragment;+++[F5GZS6_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000444236};+++[F5H056_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000438353}; Flags: Fragment;+++[F5H0E2_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000438032}; Flags: Fragment;+++[F5H867_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000442135}; Flags: Fragment;+++[H0YFS2_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000440001}; Flags: Fragment;+++[H0YFX4_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000440819}; Flags: Fragment;+++[H0YH36_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000445858}; Flags: Fragment;+++[J3KPF3_HUMAN|Unreviewed]SubName: Full=4F2 cell-surface antigen heavy chain {ECO:0000313|Ensembl:ENSP00000367123}; SubName: Full=Solute carrier family 3 (Activators of dibasic and neutral amino acid transport), member 2, isoform CRA_a {ECO:0000313|EMBL:EAW74118.1};"]
[65264,"'UBE2Z'",2576,3065,2820.5,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005764///lysosome+++GO:0005634///nucleus","GO:0005524///ATP binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0004869///cysteine-type endopeptidase inhibitor activity+++GO:0000166///nucleotide binding","GO:0043066///negative regulation of apoptotic process+++GO:0030163///protein catabolic process+++GO:0032940///secretion by cell+++GO:0043065///positive regulation of apoptotic process+++GO:0016192///vesicle-mediated transport+++GO:0010951///negative regulation of endopeptidase activity+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006915///apoptotic process+++GO:0015031///protein transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER+++GO:0016567///protein ubiquitination+++GO:0007041///lysosomal transport","IPR016135///Ubiquitin-conjugating enzyme/RWD-like+++IPR000608///Ubiquitin-conjugating enzyme E2","[UBE2Z_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 Z; EC=2.3.2.23; AltName: Full=E2 ubiquitin-conjugating enzyme Z; AltName: Full=Uba6-specific E2 conjugating enzyme 1; Short=Use1; AltName: Full=Ubiquitin carrier protein Z; AltName: Full=Ubiquitin-protein ligase Z;+++[D3DTW2_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2Z (Putative), isoform CRA_a {ECO:0000313|EMBL:EAW94704.1};+++[D6RB11_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 Z {ECO:0000313|Ensembl:ENSP00000424543}; Flags: Fragment;+++[G8JLK1_HUMAN|Unreviewed]SubName: Full=Vesicle transport protein USE1 {ECO:0000313|Ensembl:ENSP00000390287};+++[H0Y9X8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 Z {ECO:0000313|Ensembl:ENSP00000425398}; Flags: Fragment;+++[I3L286_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 Z {ECO:0000313|Ensembl:ENSP00000459473}; Flags: Fragment;+++[I3L3V3_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 Z {ECO:0000313|Ensembl:ENSP00000460759};+++[I3L4C5_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 Z {ECO:0000313|Ensembl:ENSP00000461147}; Flags: Fragment;+++[M0QYT5_HUMAN|Unreviewed]SubName: Full=Vesicle transport protein USE1 {ECO:0000313|Ensembl:ENSP00000470065}; Flags: Fragment;+++[M0QZE0_HUMAN|Unreviewed]SubName: Full=Vesicle transport protein USE1 {ECO:0000313|Ensembl:ENSP00000470487};+++[M0QZZ6_HUMAN|Unreviewed]SubName: Full=Vesicle transport protein USE1 {ECO:0000313|Ensembl:ENSP00000470882};"]
[653140,"'FAM228A'",1,5,3,{"$nulls":7},"IPR040046///Protein FAM228","[F228A_HUMAN|Reviewed]RecName: Full=Protein FAM228A;+++[F2Z3J0_HUMAN|Unreviewed]SubName: Full=Protein FAM228A {ECO:0000313|Ensembl:ENSP00000401257};+++[H7C3M9_HUMAN|Unreviewed]SubName: Full=Protein FAM228A {ECO:0000313|Ensembl:ENSP00000412833}; Flags: Fragment;+++[H7C4B8_HUMAN|Unreviewed]SubName: Full=Protein FAM228A {ECO:0000313|Ensembl:ENSP00000416595}; Flags: Fragment;"]
[653519,"'GPR89A'",178.31,240.68,209.495,{"$nulls":4},"GO:0016020///membrane+++GO:0032580///Golgi cisterna membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0030660///Golgi-associated vesicle membrane","GO:0005244///voltage-gated ion channel activity+++GO:0008308///voltage-gated anion channel activity","GO:0006811///ion transport+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0015698///inorganic anion transport+++GO:0015031///protein transport+++GO:0051452///intracellular pH reduction+++GO:0034765///regulation of ion transmembrane transport+++GO:0034220///ion transmembrane transport","IPR015672///The Golgi pH regulator/GPCR-type G protein+++IPR022535///Golgi pH regulator, conserved domain+++IPR025969///Abscisic acid G-protein coupled receptor-like domain","[GPHRA_HUMAN|Reviewed]RecName: Full=Golgi pH regulator A; AltName: Full=Protein GPR89A; AltName: Full=Putative MAPK-activating protein PM01; AltName: Full=Putative NF-kappa-B-activating protein 90;+++[GPHRB_HUMAN|Reviewed]RecName: Full=Golgi pH regulator B; AltName: Full=Protein GPR89B;+++[A0A087WW78_HUMAN|Unreviewed]SubName: Full=Golgi pH regulator B {ECO:0000313|Ensembl:ENSP00000480007}; Flags: Fragment;+++[A0A087WW82_HUMAN|Unreviewed]SubName: Full=Golgi pH regulator B {ECO:0000313|Ensembl:ENSP00000480018}; Flags: Fragment;+++[E9PKY3_HUMAN|Unreviewed]SubName: Full=Golgi pH regulator A {ECO:0000313|Ensembl:ENSP00000433482};+++[E9PRZ5_HUMAN|Unreviewed]SubName: Full=Golgi pH regulator A {ECO:0000313|Ensembl:ENSP00000432212};+++[U3KPV2_HUMAN|Unreviewed]SubName: Full=Golgi pH regulator B {ECO:0000313|Ensembl:ENSP00000475253}; Flags: Fragment;+++[X5D2I6_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 89B isoform B {ECO:0000313|EMBL:AHW56489.1}; Flags: Fragment;+++[X5D329_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 89B isoform A {ECO:0000313|EMBL:AHW56709.1};+++[X5D7G6_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 89A isoform C {ECO:0000313|EMBL:AHW56487.1}; SubName: Full=G protein-coupled receptor 89B isoform C {ECO:0000313|EMBL:AHW56490.1}; Flags: Fragment;+++[X5D920_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 89A isoform B {ECO:0000313|EMBL:AHW56488.1}; Flags: Fragment;+++[X5D9J6_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 89A isoform D {ECO:0000313|EMBL:AHW56668.1};+++[X5DNN3_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor 89B isoform D {ECO:0000313|EMBL:AHW56491.1}; Flags: Fragment;"]
[6541,"'SLC7A1'",2341,2785,2563,"05206///MicroRNAs in cancer",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0005515///protein binding+++GO:0015171///amino acid transmembrane transporter activity+++GO:0000064///L-ornithine transmembrane transporter activity+++GO:0015181///arginine transmembrane transporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015189///L-lysine transmembrane transporter activity","GO:0015809///arginine transport+++GO:1903352///L-ornithine transmembrane transport+++GO:1903826///arginine transmembrane transport+++GO:0097638///L-arginine import across plasma membrane+++GO:1903401///L-lysine transmembrane transport+++GO:0006865///amino acid transport+++GO:0055085///transmembrane transport","IPR002293///Amino acid/polyamine transporter I+++IPR004755///Cationic amino acid transport permease+++IPR029485///Cationic amino acid transporter, C-terminal","[CTR1_HUMAN|Reviewed]RecName: Full=High affinity cationic amino acid transporter 1; Short=CAT-1 {ECO:0000303|PubMed:10485994}; Short=CAT1; AltName: Full=Ecotropic retroviral leukemia receptor homolog; AltName: Full=Ecotropic retrovirus receptor homolog; AltName: Full=Solute carrier family 7 member 1 {ECO:0000312|HGNC:HGNC:11057}; AltName: Full=System Y+ basic amino acid transporter;+++[A0A024RDQ9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 1, isoform CRA_a {ECO:0000313|EMBL:EAX08444.1};+++[A0A0A8K9B7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 1 {ECO:0000313|EMBL:BAQ19762.1};+++[Q5JR49_HUMAN|Unreviewed]SubName: Full=High affinity cationic amino acid transporter 1 {ECO:0000313|Ensembl:ENSP00000390092}; Flags: Fragment;"]
[6550,"'SLC9A3'",80,81,80.5,"04976///Bile secretion+++04978///Mineral absorption+++04974///Protein digestion and absorption+++04964///Proximal tubule bicarbonate reclamation","H01174///Congenital diarrhea",null,null,"GO:0009986///cell surface+++GO:0031982///vesicle+++GO:0005886///plasma membrane+++GO:0005903///brush border+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0031526///brush border membrane+++GO:0016324///apical plasma membrane","GO:0015299///solute:proton antiporter activity+++GO:0030165///PDZ domain binding+++GO:0015297///antiporter activity+++GO:0015385///sodium:proton antiporter activity+++GO:0015386///potassium:proton antiporter activity+++GO:0005515///protein binding","GO:0071805///potassium ion transmembrane transport+++GO:0051453///regulation of intracellular pH+++GO:1902600///proton transmembrane transport+++GO:0055085///transmembrane transport+++GO:0006812///cation transport+++GO:0006811///ion transport+++GO:0098719///sodium ion import across plasma membrane+++GO:0035725///sodium ion transmembrane transport+++GO:0006814///sodium ion transport+++GO:0006885///regulation of pH","IPR004709///Na+/H+ exchanger+++IPR018410///Na+/H+ exchanger, isoforms 3/5+++IPR018422///Cation/H+ exchanger, CPA1 family+++IPR006153///Cation/H+ exchanger","[SL9A3_HUMAN|Reviewed]RecName: Full=Sodium/hydrogen exchanger 3 {ECO:0000305}; AltName: Full=Na(+)/H(+) exchanger 3 {ECO:0000303|PubMed:7631746}; Short=NHE-3 {ECO:0000303|PubMed:7631746}; AltName: Full=Solute carrier family 9 member 3;+++[A0A0G2JQZ3_HUMAN|Unreviewed]SubName: Full=Sodium/hydrogen exchanger 3 {ECO:0000313|Ensembl:ENSP00000486297}; Flags: Fragment;+++[A0A2R8Y780_HUMAN|Unreviewed]RecName: Full=Sodium/hydrogen exchanger {ECO:0000256|RuleBase:RU003722};+++[Q8NHH7_HUMAN|Unreviewed]SubName: Full=Mini-cistron {ECO:0000313|EMBL:AAM53436.1};"]
[6575,"'SLC20A2'",1684.8,1344,1514.4,"05016///Huntington's disease+++04218///Cellular senescence+++04979///Cholesterol metabolism+++05203///Viral carcinogenesis+++05012///Parkinson's disease+++04217///Necroptosis+++04020///Calcium signaling pathway+++04216///Ferroptosis+++05166///HTLV-I infection+++04022///cGMP-PKG signaling pathway+++04621///NOD-like receptor signaling pathway+++05161///Hepatitis B","H01574///Familial idiopathic basal ganglia calcification",null,null,"GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0038023///signaling receptor activity+++GO:0015293///symporter activity+++GO:0001618///virus receptor activity+++GO:0005436///sodium:phosphate symporter activity+++GO:0015321///sodium-dependent phosphate transmembrane transporter activity+++GO:0005315///inorganic phosphate transmembrane transporter activity+++GO:0015319///sodium:inorganic phosphate symporter activity","GO:0046718///viral entry into host cell+++GO:0035725///sodium ion transmembrane transport+++GO:0006811///ion transport+++GO:0055085///transmembrane transport+++GO:0044341///sodium-dependent phosphate transport+++GO:0006817///phosphate ion transport+++GO:0006814///sodium ion transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0016032///viral process","IPR001204///Phosphate transporter","[S20A2_HUMAN|Reviewed]RecName: Full=Sodium-dependent phosphate transporter 2; AltName: Full=Gibbon ape leukemia virus receptor 2; Short=GLVR-2; AltName: Full=Phosphate transporter 2; Short=PiT-2; Short=Pit2; Short=hPit2; AltName: Full=Solute carrier family 20 member 2;+++[B2RBR4_HUMAN|Unreviewed]RecName: Full=Phosphate transporter {ECO:0000256|RuleBase:RU363058};+++[B4DJ71_HUMAN|Unreviewed]RecName: Full=Phosphate transporter {ECO:0000256|RuleBase:RU363058};+++[E5RGG8_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transporter 2 {ECO:0000313|Ensembl:ENSP00000430166}; Flags: Fragment;+++[E5RGJ6_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transporter 2 {ECO:0000313|Ensembl:ENSP00000427756}; Flags: Fragment;+++[E5RGM8_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transporter 2 {ECO:0000313|Ensembl:ENSP00000429989};+++[E5RIX1_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transporter 2 {ECO:0000313|Ensembl:ENSP00000429299}; Flags: Fragment;+++[E5RJW9_HUMAN|Unreviewed]SubName: Full=Sodium-dependent phosphate transporter 2 {ECO:0000313|Ensembl:ENSP00000430462}; Flags: Fragment;"]
[6594,"'SMARCA1'",783,846,814.5,{"$nulls":4},"GO:0000790///nuclear chromatin+++GO:0005634///nucleus+++GO:0016589///NURF complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005654///nucleoplasm+++GO:0090537///CERF complex","GO:0036310///annealing helicase activity+++GO:0031491///nucleosome binding+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0016787///hydrolase activity+++GO:0016818///hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides+++GO:0005515///protein binding+++GO:0016887///ATPase activity+++GO:0003676///nucleic acid binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0004386///helicase activity+++GO:0000166///nucleotide binding+++GO:0070615///nucleosome-dependent ATPase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005524///ATP binding","GO:0007420///brain development+++GO:0006325///chromatin organization+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000733///DNA strand renaturation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0030182///neuron differentiation+++GO:0006338///chromatin remodeling+++GO:2000177///regulation of neural precursor cell proliferation","IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR029915///ISWI family+++IPR015195///SLIDE domain+++IPR001005///SANT/Myb domain+++IPR038718///SNF2-like, N-terminal domain superfamily+++IPR036306///ISWI, HAND domain superfamily+++IPR015194///ISWI, HAND domain+++IPR009057///Homeobox-like domain superfamily+++IPR000330///SNF2-related, N-terminal domain+++IPR001650///Helicase, C-terminal+++IPR020838///DBINO domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR017884///SANT domain","[SMCA1_HUMAN|Reviewed]RecName: Full=Probable global transcription activator SNF2L1; EC=3.6.4.-; AltName: Full=ATP-dependent helicase SMARCA1; AltName: Full=Nucleosome-remodeling factor subunit SNF2L; AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1;+++[A0A0A0MRP6_HUMAN|Unreviewed]SubName: Full=Probable global transcription activator SNF2L1 {ECO:0000313|Ensembl:ENSP00000360164};+++[B7ZLQ5_HUMAN|Unreviewed]SubName: Full=Probable global transcription activator SNF2L1 {ECO:0000313|Ensembl:ENSP00000360162}; SubName: Full=SMARCA1 protein {ECO:0000313|EMBL:AAI43955.1}; SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1, isoform CRA_d {ECO:0000313|EMBL:EAX11836.1};+++[Q86UA8_HUMAN|Unreviewed]SubName: Full=SMARCA1 protein {ECO:0000313|EMBL:AAH51825.2}; Flags: Fragment;"]
[65988,"'ZNF747'",127,149,138,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0005665///RNA polymerase II, core complex+++GO:0005622///intracellular","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type+++IPR036051///KRAB domain superfamily","[ZN747_HUMAN|Reviewed]RecName: Full=KRAB domain-containing protein ZNF747;+++[A0A024QZG5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW52240.1};+++[B7Z5R0_HUMAN|Unreviewed]SubName: Full=KRAB domain-containing protein ZNF747 {ECO:0000313|Ensembl:ENSP00000457274}; SubName: Full=cDNA FLJ54920, moderately similar to Homo sapiens zinc finger protein 689 (ZNF689), mRNA {ECO:0000313|EMBL:BAH12996.1};+++[B7ZAD9_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79153, highly similar to Homo sapiens zinc finger protein 689 (ZNF689), mRNA {ECO:0000313|EMBL:BAH14625.1};"]
[6602,"'SMARCD1'",1169,1136,1152.5,"05225///Hepatocellular carcinoma+++04714///Thermogenesis","H02024///Neutrophil specific granule deficiency",null,null,"GO:0016514///SWI/SNF complex+++GO:0071565///nBAF complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0071564///npBAF complex+++GO:0043231///intracellular membrane-bounded organelle","GO:0005102///signaling receptor binding+++GO:0003682///chromatin binding+++GO:0003713///transcription coactivator activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding","GO:0007399///nervous system development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071398///cellular response to fatty acid+++GO:0006338///chromatin remodeling+++GO:0006337///nucleosome disassembly+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0006325///chromatin organization","IPR003121///SWIB/MDM2 domain+++IPR036885///SWIB/MDM2 domain superfamily+++IPR038041///SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1+++IPR019835///SWIB domain","[SMRD1_HUMAN|Reviewed]RecName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1; AltName: Full=60 kDa BRG-1/Brm-associated factor subunit A; AltName: Full=BRG1-associated factor 60A; Short=BAF60A; AltName: Full=SWI/SNF complex 60 kDa subunit;+++[A0A024R102_HUMAN|Unreviewed]SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, isoform CRA_e {ECO:0000313|EMBL:EAW58127.1};+++[A0A024R137_HUMAN|Unreviewed]SubName: Full=SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, isoform CRA_c {ECO:0000313|EMBL:EAW58124.1};+++[F8VRQ4_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 {ECO:0000313|Ensembl:ENSP00000448627};+++[F8VUB0_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 {ECO:0000313|Ensembl:ENSP00000448030}; Flags: Fragment;+++[F8VW95_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 {ECO:0000313|Ensembl:ENSP00000449825}; Flags: Fragment;+++[F8VZ70_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 {ECO:0000313|Ensembl:ENSP00000447386}; Flags: Fragment;+++[H0YHV1_HUMAN|Unreviewed]SubName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 {ECO:0000313|Ensembl:ENSP00000447909}; Flags: Fragment;+++[L8EC99_HUMAN|Unreviewed]SubName: Full=Alternative protein SMARCD1 {ECO:0000313|EMBL:CCQ43197.1};"]
[6615,"'SNAI1'",40,44,42,"04520///Adherens junction",{"$nulls":3},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005721///pericentric heterochromatin","GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0019900///kinase binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0043565///sequence-specific DNA binding+++GO:0070888///E-box binding","GO:0043518///negative regulation of DNA damage response, signal transduction by p53 class mediator+++GO:0061314///Notch signaling involved in heart development+++GO:0007498///mesoderm development+++GO:0060536///cartilage morphogenesis+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010957///negative regulation of vitamin D biosynthetic process+++GO:1902230///negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0060021///roof of mouth development+++GO:0070828///heterochromatin organization+++GO:0001649///osteoblast differentiation+++GO:0007275///multicellular organism development+++GO:0060972///left/right pattern formation+++GO:0016477///cell migration+++GO:0001707///mesoderm formation+++GO:0030335///positive regulation of cell migration+++GO:0003198///epithelial to mesenchymal transition involved in endocardial cushion formation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0031069///hair follicle morphogenesis+++GO:0003180///aortic valve morphogenesis+++GO:0001837///epithelial to mesenchymal transition+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060806///negative regulation of cell differentiation involved in embryonic placenta development+++GO:0010718///positive regulation of epithelial to mesenchymal transition+++GO:0060707///trophoblast giant cell differentiation+++GO:2000810///regulation of bicellular tight junction assembly+++GO:0045892///negative regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[SNAI1_HUMAN|Reviewed]RecName: Full=Zinc finger protein SNAI1; AltName: Full=Protein snail homolog 1; Short=Protein sna;"]
[663,"'BNIP2'",352,420.35,386.175,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031616///spindle pole centrosome+++GO:0005737///cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016021///integral component of membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005814///centriole","GO:0005096///GTPase activator activity+++GO:0004309///exopolyphosphatase activity+++GO:0005515///protein binding+++GO:0005509///calcium ion binding","GO:0043410///positive regulation of MAPK cascade+++GO:0045666///positive regulation of neuron differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0043547///positive regulation of GTPase activity+++GO:0006798///polyphosphate catabolic process+++GO:0001824///blastocyst development+++GO:0051057///positive regulation of small GTPase mediated signal transduction+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0051146///striated muscle cell differentiation+++GO:0007098///centrosome cycle+++GO:0006915///apoptotic process","IPR022181///Bcl2-/adenovirus E1B 19kDa-interacting protein 2+++IPR036865///CRAL-TRIO lipid binding domain superfamily+++IPR001251///CRAL-TRIO lipid binding domain","[BNIP2_HUMAN|Reviewed]RecName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2;+++[H7C096_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000393644}; Flags: Fragment;+++[H7C142_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000398364}; Flags: Fragment;+++[J3KN59_HUMAN|Unreviewed]SubName: Full=BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000267859};"]
[6646,"'SOAT1'",385,356,370.5,"00100///Steroid biosynthesis+++04979///Cholesterol metabolism",null,null,"R01461///Acyl-CoA:cholesterol O-acyltransferase   Acyl-CoA + Cholesterol <=> CoA + Cholesterol ester","GO:0005759///mitochondrial matrix+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005739///mitochondrion","GO:0003824///catalytic activity+++GO:0005515///protein binding+++GO:0000062///fatty-acyl-CoA binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0015485///cholesterol binding+++GO:0003985///acetyl-CoA C-acetyltransferase activity+++GO:0016830///carbon-carbon lyase activity+++GO:0050662///coenzyme binding+++GO:0003988///acetyl-CoA C-acyltransferase activity+++GO:0008374///O-acyltransferase activity+++GO:0046872///metal ion binding+++GO:0016885///ligase activity, forming carbon-carbon bonds+++GO:0019899///enzyme binding+++GO:0016740///transferase activity+++GO:0004772///sterol O-acyltransferase activity+++GO:0042803///protein homodimerization activity+++GO:0016747///transferase activity, transferring acyl groups other than amino-acyl groups+++GO:0034736///cholesterol O-acyltransferase activity","GO:1902224///ketone body metabolic process+++GO:0046951///ketone body biosynthetic process+++GO:0034383///low-density lipoprotein particle clearance+++GO:0033344///cholesterol efflux+++GO:0051260///protein homooligomerization+++GO:0015937///coenzyme A biosynthetic process+++GO:0034435///cholesterol esterification+++GO:0072229///metanephric proximal convoluted tubule development+++GO:0008203///cholesterol metabolic process+++GO:0001889///liver development+++GO:0010742///macrophage derived foam cell differentiation+++GO:0009083///branched-chain amino acid catabolic process+++GO:0007420///brain development+++GO:0008202///steroid metabolic process+++GO:0006629///lipid metabolic process+++GO:0015936///coenzyme A metabolic process+++GO:0042594///response to starvation+++GO:1902860///propionyl-CoA biosynthetic process+++GO:0006085///acetyl-CoA biosynthetic process+++GO:0034379///very-low-density lipoprotein particle assembly+++GO:0006550///isoleucine catabolic process+++GO:0009725///response to hormone+++GO:0042986///positive regulation of amyloid precursor protein biosynthetic process+++GO:0042632///cholesterol homeostasis+++GO:0060612///adipose tissue development+++GO:0046952///ketone body catabolic process+++GO:0046356///acetyl-CoA catabolic process+++GO:0014070///response to organic cyclic compound+++GO:0006635///fatty acid beta-oxidation+++GO:0010878///cholesterol storage","IPR030687///Sterol O-acyltransferase, metazoa+++IPR014371///Sterol O-acyltransferase, ACAT/DAG/ARE types+++IPR004299///Membrane bound O-acyl transferase, MBOAT","[SOAT1_HUMAN|Reviewed]RecName: Full=Sterol O-acyltransferase 1; EC=2.3.1.26 {ECO:0000269|PubMed:18480028}; AltName: Full=Acyl-coenzyme A:cholesterol acyltransferase 1; Short=ACAT-1; AltName: Full=Cholesterol acyltransferase 1;+++[B1APM4_HUMAN|Unreviewed]SubName: Full=Sterol O-acyltransferase 1 {ECO:0000313|Ensembl:ENSP00000411309}; Flags: Fragment;+++[E9PKF3_HUMAN|Unreviewed]SubName: Full=Acetyl-CoA acetyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000433568}; Flags: Fragment;+++[E9PRQ6_HUMAN|Unreviewed]SubName: Full=Acetyl-CoA acetyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000435965};+++[H0YEL7_HUMAN|Unreviewed]SubName: Full=Acetyl-CoA acetyltransferase, mitochondrial {ECO:0000313|Ensembl:ENSP00000436096}; Flags: Fragment;"]
[6660,"'SOX5'",42,72,57,null,"H02156///Lamb-Shaffer syndrome",null,null,"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0061036///positive regulation of cartilage development+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0045165///cell fate commitment+++GO:0055059///asymmetric neuroblast division+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0006366///transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2000741///positive regulation of mesenchymal stem cell differentiation","IPR009071///High mobility group box domain+++IPR036910///High mobility group box domain superfamily","[SOX5_HUMAN|Reviewed]RecName: Full=Transcription factor SOX-5;+++[A0A024RB06_HUMAN|Unreviewed]SubName: Full=SRY (Sex determining region Y)-box 5, isoform CRA_a {ECO:0000313|EMBL:EAW96490.1};+++[A0A2R8Y5Q1_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 {ECO:0000313|Ensembl:ENSP00000494627}; Flags: Fragment;+++[A0A2R8Y7P3_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 {ECO:0000313|Ensembl:ENSP00000496161}; Flags: Fragment;+++[F5GWL1_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 {ECO:0000313|Ensembl:ENSP00000441579}; Flags: Fragment;+++[F5H0I3_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 {ECO:0000313|Ensembl:ENSP00000439832};+++[F5H876_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 {ECO:0000313|Ensembl:ENSP00000442119};+++[G3V0H1_HUMAN|Unreviewed]SubName: Full=SRY (Sex determining region Y)-box 5, isoform CRA_f {ECO:0000313|EMBL:EAW96492.1}; SubName: Full=Transcription factor SOX-5 {ECO:0000313|Ensembl:ENSP00000393240};+++[I3L0A5_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 {ECO:0000313|Ensembl:ENSP00000356174};+++[Q6IBT9_HUMAN|Unreviewed]SubName: Full=SOX5 protein {ECO:0000313|EMBL:CAG32994.1};+++[T2CYZ2_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 variant 6 {ECO:0000313|EMBL:AGV38565.1};+++[T2CZM2_HUMAN|Unreviewed]SubName: Full=Transcription factor SOX-5 variant 7 {ECO:0000313|EMBL:AGV38566.1};"]
[6662,"'SOX9'",1997,2060,2028.5,"04024///cAMP signaling pathway","H00607///46,XY disorders of sex development (Disorders of gonadal development)+++H00598///46,XX disorders of sex development (Disorders of gonadal development)+++H00442///Campomelic dysplasia (CD)",null,null,"GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm+++GO:0032991///protein-containing complex+++GO:0005634///nucleus+++GO:0044798///nuclear transcription factor complex","GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0003682///chromatin binding+++GO:0046982///protein heterodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0034236///protein kinase A catalytic subunit binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043425///bHLH transcription factor binding+++GO:0097157///pre-mRNA intronic binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0005515///protein binding+++GO:0035326///enhancer binding+++GO:0003677///DNA binding+++GO:0008013///beta-catenin binding","GO:0061145///lung smooth muscle development+++GO:0060512///prostate gland morphogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060221///retinal rod cell differentiation+++GO:0001502///cartilage condensation+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0071773///cellular response to BMP stimulus+++GO:0072170///metanephric tubule development+++GO:0002009///morphogenesis of an epithelium+++GO:0034504///protein localization to nucleus+++GO:0043066///negative regulation of apoptotic process+++GO:0002063///chondrocyte development+++GO:0002062///chondrocyte differentiation+++GO:0043491///protein kinase B signaling+++GO:0042981///regulation of apoptotic process+++GO:0061036///positive regulation of cartilage development+++GO:0001837///epithelial to mesenchymal transition+++GO:0061046///regulation of branching involved in lung morphogenesis+++GO:0030154///cell differentiation+++GO:0032808///lacrimal gland development+++GO:0001501///skeletal system development+++GO:0035622///intrahepatic bile duct development+++GO:0070168///negative regulation of biomineral tissue development+++GO:0030903///notochord development+++GO:0048709///oligodendrocyte differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:2000794///regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0003203///endocardial cushion morphogenesis+++GO:0046533///negative regulation of photoreceptor cell differentiation+++GO:0060534///trachea cartilage development+++GO:0072190///ureter urothelium development+++GO:0042127///regulation of cell proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0010564///regulation of cell cycle process+++GO:0072189///ureter development+++GO:0006338///chromatin remodeling+++GO:0060441///epithelial tube branching involved in lung morphogenesis+++GO:0060532///bronchus cartilage development+++GO:0010628///positive regulation of gene expression+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045732///positive regulation of protein catabolic process+++GO:0019933///cAMP-mediated signaling+++GO:0003180///aortic valve morphogenesis+++GO:0030198///extracellular matrix organization+++GO:0019100///male germ-line sex determination+++GO:0014036///neural crest cell fate specification+++GO:0008584///male gonad development+++GO:0060729///intestinal epithelial structure maintenance+++GO:0001503///ossification+++GO:0030279///negative regulation of ossification+++GO:0032332///positive regulation of chondrocyte differentiation+++GO:0045595///regulation of cell differentiation+++GO:0060350///endochondral bone morphogenesis+++GO:0070371///ERK1 and ERK2 cascade+++GO:0002683///negative regulation of immune system process+++GO:0051216///cartilage development+++GO:0007010///cytoskeleton organization+++GO:0001894///tissue homeostasis+++GO:0060784///regulation of cell proliferation involved in tissue homeostasis+++GO:0060018///astrocyte fate commitment+++GO:0003188///heart valve formation+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0035019///somatic stem cell population maintenance+++GO:0030879///mammary gland development+++GO:0007219///Notch signaling pathway+++GO:0072034///renal vesicle induction+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060008///Sertoli cell differentiation+++GO:0003179///heart valve morphogenesis+++GO:0002053///positive regulation of mesenchymal cell proliferation+++GO:2000020///positive regulation of male gonad development+++GO:0097065///anterior head development+++GO:0060487///lung epithelial cell differentiation+++GO:0007165///signal transduction+++GO:0060041///retina development in camera-type eye+++GO:0070384///Harderian gland development+++GO:0008284///positive regulation of cell proliferation+++GO:0030916///otic vesicle formation+++GO:0072197///ureter morphogenesis+++GO:0007417///central nervous system development+++GO:0010629///negative regulation of gene expression+++GO:0006334///nucleosome assembly+++GO:2000741///positive regulation of mesenchymal stem cell differentiation+++GO:0010634///positive regulation of epithelial cell migration+++GO:0071300///cellular response to retinoic acid+++GO:0003415///chondrocyte hypertrophy+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0001942///hair follicle development+++GO:0098609///cell-cell adhesion+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:1901203///positive regulation of extracellular matrix assembly+++GO:0014032///neural crest cell development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0030238///male sex determination+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0072193///ureter smooth muscle cell differentiation+++GO:0031018///endocrine pancreas development+++GO:0065003///protein-containing complex assembly+++GO:0060517///epithelial cell proliferation involved in prostatic bud elongation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0007507///heart development+++GO:0003413///chondrocyte differentiation involved in endochondral bone morphogenesis+++GO:0001708///cell fate specification+++GO:0032331///negative regulation of chondrocyte differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007283///spermatogenesis+++GO:0060009///Sertoli cell development+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0048873///homeostasis of number of cells within a tissue+++GO:0001934///positive regulation of protein phosphorylation+++GO:0090103///cochlea morphogenesis+++GO:0045165///cell fate commitment+++GO:0014068///positive regulation of phosphatidylinositol 3-kinase signaling+++GO:0061138///morphogenesis of a branching epithelium+++GO:0090184///positive regulation of kidney development+++GO:0030155///regulation of cell adhesion+++GO:0045662///negative regulation of myoblast differentiation+++GO:2001054///negative regulation of mesenchymal cell apoptotic process+++GO:0060174///limb bud formation+++GO:0071504///cellular response to heparin+++GO:2000138///positive regulation of cell proliferation involved in heart morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030850///prostate gland development+++GO:0072289///metanephric nephron tubule formation+++GO:0030858///positive regulation of epithelial cell differentiation+++GO:0071347///cellular response to interleukin-1+++GO:0090190///positive regulation of branching involved in ureteric bud morphogenesis+++GO:0071260///cellular response to mechanical stimulus+++GO:0030502///negative regulation of bone mineralization+++GO:0071599///otic vesicle development+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0003170///heart valve development","IPR029548///Transcription factor SOX-9+++IPR022151///Sox developmental protein N-terminal+++IPR036910///High mobility group box domain superfamily+++IPR009071///High mobility group box domain","[SOX9_HUMAN|Reviewed]RecName: Full=Transcription factor SOX-9 {ECO:0000305};+++[A0A0U4U3E8_HUMAN|Unreviewed]SubName: Full=SRY (Sex determining region Y)-box9 {ECO:0000313|EMBL:BAS29568.1}; Flags: Fragment;+++[A0A0U4YWA5_HUMAN|Unreviewed]SubName: Full=SRY (Sex determining region Y)-box9 {ECO:0000313|EMBL:BAS29567.1}; Flags: Fragment;+++[S6CBB2_HUMAN|Unreviewed]SubName: Full=Transcription factor {ECO:0000313|EMBL:BAN66330.1}; Flags: Fragment;+++[U5XJY7_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62958.1}; Flags: Fragment;+++[U5XJZ1_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62963.1}; Flags: Fragment;+++[U5XJZ4_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62968.1}; Flags: Fragment;+++[U5XK44_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62957.1}; Flags: Fragment;+++[U5XK50_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62962.1}; Flags: Fragment;+++[U5XKW5_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62956.1}; Flags: Fragment;+++[U5XKW9_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62961.1}; Flags: Fragment;+++[U5XMM4_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62959.1}; Flags: Fragment;+++[U5XN63_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62955.1}; Flags: Fragment;+++[U5XN67_HUMAN|Unreviewed]SubName: Full=SRY-box 9 {ECO:0000313|EMBL:AGZ62960.1}; Flags: Fragment;"]
[668,"'FOXL2'",43,28,35.5,null,"H00826///Blepharophimosis-ptosis-epicanthus inversus syndrome (BPES)+++H00627///Premature ovarian failure",null,null,"GO:0005654///nucleoplasm+++GO:0045171///intercellular bridge+++GO:0005634///nucleus","GO:0030331///estrogen receptor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0043028///cysteine-type endopeptidase regulator activity involved in apoptotic process+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0043565///sequence-specific DNA binding","GO:0043065///positive regulation of apoptotic process+++GO:0008585///female gonad development+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0060014///granulosa cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007338///single fertilization+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006309///apoptotic DNA fragmentation+++GO:0030154///cell differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0002074///extraocular skeletal muscle development+++GO:0043280///positive regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0046881///positive regulation of follicle-stimulating hormone secretion+++GO:0009653///anatomical structure morphogenesis+++GO:0060065///uterus development+++GO:0001541///ovarian follicle development+++GO:0019101///female somatic sex determination+++GO:0033686///positive regulation of luteinizing hormone secretion+++GO:0001555///oocyte growth+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048048///embryonic eye morphogenesis","IPR036390///Winged helix DNA-binding domain superfamily+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR001766///Fork head domain+++IPR030456///Fork head domain conserved site 2+++IPR018122///Fork head domain conserved site1","[FOXL2_HUMAN|Reviewed]RecName: Full=Forkhead box protein L2;+++[Q05CX9_HUMAN|Unreviewed]SubName: Full=FOXL2 protein {ECO:0000313|EMBL:AAH19896.1}; Flags: Fragment;+++[Q4JHB5_HUMAN|Unreviewed]SubName: Full=Transcription factor FOXL2 mutant 3 {ECO:0000313|EMBL:AAY89236.1};+++[Q4JHB6_HUMAN|Unreviewed]SubName: Full=Transcription factor FOXL2 mutant 2 {ECO:0000313|EMBL:AAY89235.1};+++[Q4JHB7_HUMAN|Unreviewed]SubName: Full=Transcription factor FOXL2 mutant 1 {ECO:0000313|EMBL:AAY89234.1};+++[Q53ZD3_HUMAN|Unreviewed]SubName: Full=FOXL2 {ECO:0000313|EMBL:AAY21821.1}; SubName: Full=Forkhead box L2 {ECO:0000313|EMBL:AAQ01519.1};"]
[6707,"'SPRR3'",0,4,2,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0001533///cornified envelope","GO:0005515///protein binding+++GO:0005198///structural molecule activity","GO:0042060///wound healing+++GO:0030216///keratinocyte differentiation+++GO:0070268///cornification+++GO:0008544///epidermis development+++GO:0031424///keratinization+++GO:0018149///peptide cross-linking","IPR026075///Small proline-rich protein/late cornified envelope protein","[SPRR3_HUMAN|Reviewed]RecName: Full=Small proline-rich protein 3; AltName: Full=22 kDa pancornulin; AltName: Full=Cornifin beta; AltName: Full=Esophagin;+++[B1AN48_HUMAN|Unreviewed]SubName: Full=Small proline-rich protein 3 {ECO:0000313|Ensembl:ENSP00000402016}; Flags: Fragment;"]
[6726,"'SRP9'",1545,1883,1714,"03060///Protein export",{"$nulls":3},"GO:0005786///signal recognition particle, endoplasmic reticulum targeting+++GO:0005785///signal recognition particle receptor complex+++GO:0005829///cytosol+++GO:0048500///signal recognition particle+++GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0005047///signal recognition particle binding+++GO:0008312///7S RNA binding","GO:0045900///negative regulation of translational elongation+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0006616///SRP-dependent cotranslational protein targeting to membrane, translocation","IPR008832///Signal recognition particle, SRP9 subunit+++IPR039432///SRP9 domain+++IPR039914///Signal recognition particle SRP9/Srp21+++IPR009018///Signal recognition particle, SRP9/SRP14 subunit","[SRP09_HUMAN|Reviewed]RecName: Full=Signal recognition particle 9 kDa protein; Short=SRP9;+++[A0A024R3P3_HUMAN|Unreviewed]SubName: Full=Signal recognition particle 9kDa, isoform CRA_b {ECO:0000313|EMBL:EAW69752.1};+++[E9PE20_HUMAN|Unreviewed]SubName: Full=Signal recognition particle 9 kDa protein {ECO:0000313|Ensembl:ENSP00000355803};+++[Q6P2S0_HUMAN|Unreviewed]SubName: Full=SRP9 protein {ECO:0000313|EMBL:AAH64351.1};"]
[6745,"'SSR1'",2912,3744,3328,"04141///Protein processing in endoplasmic reticulum",null,"M00402///Translocon-associated protein (TRAP) complex",null,"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding","GO:0008284///positive regulation of cell proliferation+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0006613///cotranslational protein targeting to membrane","IPR005595///Translocon-associated protein (TRAP), alpha subunit","[SSRA_HUMAN|Reviewed]RecName: Full=Translocon-associated protein subunit alpha; Short=TRAP-alpha; AltName: Full=Signal sequence receptor subunit alpha; Short=SSR-alpha; Flags: Precursor;+++[C9IZQ1_HUMAN|Unreviewed]SubName: Full=Translocon-associated protein subunit alpha {ECO:0000313|Ensembl:ENSP00000418617};+++[C9J3L8_HUMAN|Unreviewed]SubName: Full=Translocon-associated protein subunit alpha {ECO:0000313|Ensembl:ENSP00000417290};+++[C9J5W0_HUMAN|Unreviewed]SubName: Full=Translocon-associated protein subunit alpha {ECO:0000313|Ensembl:ENSP00000417911};+++[C9JBX5_HUMAN|Unreviewed]SubName: Full=Translocon-associated protein subunit alpha {ECO:0000313|Ensembl:ENSP00000420730};+++[C9JY01_HUMAN|Unreviewed]SubName: Full=Translocon-associated protein subunit alpha {ECO:0000313|Ensembl:ENSP00000419953}; Flags: Fragment;+++[E9PAL7_HUMAN|Unreviewed]SubName: Full=Translocon-associated protein subunit alpha {ECO:0000313|Ensembl:ENSP00000380647};"]
[677,"'ZFP36L1'",12440,16817,14628.5,"04218///Cellular senescence",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0000126///transcription factor TFIIIB complex+++GO:0000932///P-body+++GO:1990904///ribonucleoprotein complex","GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding+++GO:0017025///TBP-class protein binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0003723///RNA binding+++GO:0035925///mRNA 3'-UTR AU-rich region binding+++GO:0000995///RNA polymerase III general transcription initiation factor activity+++GO:0005515///protein binding+++GO:0071889///14-3-3 protein binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003743///translation initiation factor activity+++GO:0017091///AU-rich element binding+++GO:0003729///mRNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0071385///cellular response to glucocorticoid stimulus+++GO:0010837///regulation of keratinocyte proliferation+++GO:0071560///cellular response to transforming growth factor beta stimulus+++GO:0006417///regulation of translation+++GO:0006402///mRNA catabolic process+++GO:0071456///cellular response to hypoxia+++GO:0071356///cellular response to tumor necrosis factor+++GO:0021915///neural tube development+++GO:0009303///rRNA transcription+++GO:0007275///multicellular organism development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0070897///transcription preinitiation complex assembly+++GO:0006915///apoptotic process+++GO:0009304///tRNA transcription+++GO:0006413///translational initiation+++GO:0031440///regulation of mRNA 3'-end processing+++GO:0035264///multicellular organism growth+++GO:0071375///cellular response to peptide hormone stimulus+++GO:0045600///positive regulation of fat cell differentiation+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0043488///regulation of mRNA stability+++GO:0061158///3'-UTR-mediated mRNA destabilization+++GO:0009611///response to wounding+++GO:0060710///chorio-allantoic fusion+++GO:0045945///positive regulation of transcription by RNA polymerase III+++GO:0071472///cellular response to salt stress+++GO:0071320///cellular response to cAMP+++GO:0007507///heart development+++GO:0071364///cellular response to epidermal growth factor stimulus+++GO:0031086///nuclear-transcribed mRNA catabolic process, deadenylation-independent decay+++GO:0045661///regulation of myoblast differentiation+++GO:0048568///embryonic organ development+++GO:0006383///transcription by RNA polymerase III+++GO:0045616///regulation of keratinocyte differentiation+++GO:0060712///spongiotrophoblast layer development+++GO:0008283///cell proliferation+++GO:0010468///regulation of gene expression+++GO:0033077///T cell differentiation in thymus+++GO:0072091///regulation of stem cell proliferation+++GO:0001570///vasculogenesis+++GO:0003342///proepicardium development+++GO:1902172///regulation of keratinocyte apoptotic process+++GO:1901991///negative regulation of mitotic cell cycle phase transition+++GO:0006384///transcription initiation from RNA polymerase III promoter+++GO:0045657///positive regulation of monocyte differentiation+++GO:0070371///ERK1 and ERK2 cascade+++GO:0000288///nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay+++GO:0014065///phosphatidylinositol 3-kinase signaling+++GO:0097403///cellular response to raffinose+++GO:0048382///mesendoderm development+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045577///regulation of B cell differentiation+++GO:0032869///cellular response to insulin stimulus+++GO:0038066///p38MAPK cascade+++GO:0043491///protein kinase B signaling+++GO:0006397///mRNA processing+++GO:1904582///positive regulation of intracellular mRNA localization+++GO:0000165///MAPK cascade+++GO:0051028///mRNA transport+++GO:1900153///positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","IPR000571///Zinc finger, CCCH-type+++IPR036855///Zinc finger, CCCH-type superfamily+++IPR007635///Tis11B-like protein, N-terminal","[TISB_HUMAN|Reviewed]RecName: Full=mRNA decay activator protein ZFP36L1 {ECO:0000305}; AltName: Full=Butyrate response factor 1 {ECO:0000303|PubMed:10367403, ECO:0000303|PubMed:12198173}; AltName: Full=EGF-response factor 1 {ECO:0000303|PubMed:8346037}; Short=ERF-1 {ECO:0000303|PubMed:8346037}; AltName: Full=TPA-induced sequence 11b {ECO:0000250|UniProtKB:P23950}; AltName: Full=Zinc finger protein 36, C3H1 type-like 1 {ECO:0000312|HGNC:HGNC:1107}; Short=ZFP36-like 1 {ECO:0000312|HGNC:HGNC:1107};+++[A0A024R658_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 36, C3H type-like 1, isoform CRA_a {ECO:0000313|EMBL:EAW80968.1};+++[B3KNA8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14140 fis, clone MAMMA1002858, highly similar to Butyrate response factor 1 {ECO:0000313|EMBL:BAG51270.1};+++[G3V2D5_HUMAN|Unreviewed]SubName: Full=mRNA decay activator protein ZFP36L1 {ECO:0000313|Ensembl:ENSP00000450600}; Flags: Fragment;+++[G3V2P5_HUMAN|Unreviewed]SubName: Full=mRNA decay activator protein ZFP36L1 {ECO:0000313|Ensembl:ENSP00000450784}; Flags: Fragment;+++[G3V382_HUMAN|Unreviewed]SubName: Full=mRNA decay activator protein ZFP36L1 {ECO:0000313|Ensembl:ENSP00000451093};+++[G3V515_HUMAN|Unreviewed]SubName: Full=mRNA decay activator protein ZFP36L1 {ECO:0000313|Ensembl:ENSP00000452119}; Flags: Fragment;"]
[6788,"'STK3'",55,39,47,"04214///Apoptosis - fly+++04010///MAPK signaling pathway+++04390///Hippo signaling pathway+++04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species",null,"M00683///Hippo signaling",null,"GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0043539///protein serine/threonine kinase activator activity+++GO:0005524///ATP binding+++GO:0046983///protein dimerization activity+++GO:0042802///identical protein binding+++GO:0003677///DNA binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0000287///magnesium ion binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0032197///transposition, RNA-mediated+++GO:0046621///negative regulation of organ growth+++GO:0006351///transcription, DNA-templated+++GO:0007346///regulation of mitotic cell cycle+++GO:0045600///positive regulation of fat cell differentiation+++GO:0032147///activation of protein kinase activity+++GO:0035329///hippo signaling+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0001841///neural tube formation+++GO:0043065///positive regulation of apoptotic process+++GO:0060800///regulation of cell differentiation involved in embryonic placenta development+++GO:0060215///primitive hemopoiesis+++GO:0060706///cell differentiation involved in embryonic placenta development+++GO:1902043///positive regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0035556///intracellular signal transduction+++GO:0097284///hepatocyte apoptotic process+++GO:0007165///signal transduction+++GO:0023014///signal transduction by protein phosphorylation+++GO:0008285///negative regulation of cell proliferation+++GO:0006310///DNA recombination+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0050821///protein stabilization+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0007417///central nervous system development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006915///apoptotic process+++GO:0003157///endocardium development+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0046330///positive regulation of JNK cascade+++GO:0006468///protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0032092///positive regulation of protein binding","IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR011524///SARAH domain+++IPR024205///Mst1 SARAH domain","[STK3_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 3; EC=2.7.11.1; AltName: Full=Mammalian STE20-like protein kinase 2; Short=MST-2; AltName: Full=STE20-like kinase MST2; AltName: Full=Serine/threonine-protein kinase Krs-1; Contains: RecName: Full=Serine/threonine-protein kinase 3 36kDa subunit; Short=MST2/N; Contains: RecName: Full=Serine/threonine-protein kinase 3 20kDa subunit; Short=MST2/C;+++[A0A087WZ06_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 3 {ECO:0000313|Ensembl:ENSP00000482260};"]
[6810,"'STX4'",562,430,496,"04130///SNARE interactions in vesicular transport+++04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0005768///endosome+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0098794///postsynapse+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0042581///specific granule+++GO:0012505///endomembrane system+++GO:0005622///intracellular+++GO:0005773///vacuole+++GO:0035749///myelin sheath adaxonal region+++GO:0016323///basolateral plasma membrane+++GO:0008021///synaptic vesicle+++GO:0030027///lamellipodium+++GO:0045202///synapse+++GO:0005802///trans-Golgi network+++GO:0042734///presynaptic membrane+++GO:0009986///cell surface+++GO:0048787///presynaptic active zone membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0036477///somatodendritic compartment+++GO:0000322///storage vacuole+++GO:0048471///perinuclear region of cytoplasm+++GO:0070062///extracellular exosome+++GO:0045335///phagocytic vesicle+++GO:0031201///SNARE complex+++GO:0016021///integral component of membrane+++GO:0043219///lateral loop+++GO:0043197///dendritic spine+++GO:0005623///cell+++GO:0005615///extracellular space+++GO:0005737///cytoplasm","GO:0000149///SNARE binding+++GO:0016230///sphingomyelin phosphodiesterase activator activity+++GO:0005484///SNAP receptor activity+++GO:0005515///protein binding","GO:0043311///positive regulation of eosinophil degranulation+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0071346///cellular response to interferon-gamma+++GO:0016192///vesicle-mediated transport+++GO:0061025///membrane fusion+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane+++GO:0035493///SNARE complex assembly+++GO:0008284///positive regulation of cell proliferation+++GO:0048284///organelle fusion+++GO:0050921///positive regulation of chemotaxis+++GO:0060291///long-term synaptic potentiation+++GO:2000010///positive regulation of protein localization to cell surface+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0033194///response to hydroperoxide+++GO:0051024///positive regulation of immunoglobulin secretion+++GO:0043085///positive regulation of catalytic activity+++GO:0006886///intracellular protein transport+++GO:0017157///regulation of exocytosis+++GO:0006836///neurotransmitter transport+++GO:1903078///positive regulation of protein localization to plasma membrane+++GO:0048278///vesicle docking+++GO:0045785///positive regulation of cell adhesion+++GO:0030335///positive regulation of cell migration+++GO:1902041///regulation of extrinsic apoptotic signaling pathway via death domain receptors+++GO:0006906///vesicle fusion+++GO:0006887///exocytosis","IPR010989///SNARE+++IPR000727///Target SNARE coiled-coil homology domain+++IPR006011///Syntaxin, N-terminal domain+++IPR006012///Syntaxin/epimorphin, conserved site","[STX4_HUMAN|Reviewed]RecName: Full=Syntaxin-4; AltName: Full=Renal carcinoma antigen NY-REN-31;+++[A0A087WWW0_HUMAN|Unreviewed]SubName: Full=Syntaxin-4 {ECO:0000313|Ensembl:ENSP00000480544}; Flags: Fragment;+++[B7Z425_HUMAN|Unreviewed]SubName: Full=Syntaxin 4A (Placental), isoform CRA_a {ECO:0000313|EMBL:EAW52175.1}; SubName: Full=cDNA FLJ57517, highly similar to Syntaxin-4 {ECO:0000313|EMBL:BAH12411.1};+++[C9JFM5_HUMAN|Unreviewed]SubName: Full=Syntaxin-4 {ECO:0000313|Ensembl:ENSP00000390788}; Flags: Fragment;+++[H3BMK2_HUMAN|Unreviewed]SubName: Full=Syntaxin-4 {ECO:0000313|Ensembl:ENSP00000454419};"]
[6832,"'SUPV3L1'",304,274,289,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045025///mitochondrial degradosome+++GO:0005739///mitochondrion+++GO:0005634///nucleus+++GO:0042645///mitochondrial nucleoid+++GO:0005759///mitochondrial matrix","GO:0003678///DNA helicase activity+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0042803///protein homodimerization activity+++GO:0003677///DNA binding+++GO:0000166///nucleotide binding+++GO:0003725///double-stranded RNA binding+++GO:0004386///helicase activity+++GO:0034458///3'-5' RNA helicase activity+++GO:0005524///ATP binding+++GO:0016817///hydrolase activity, acting on acid anhydrides","GO:0035945///mitochondrial ncRNA surveillance+++GO:0000965///mitochondrial RNA 3'-end processing+++GO:0032508///DNA duplex unwinding+++GO:0030307///positive regulation of cell growth+++GO:0070827///chromatin maintenance+++GO:0035946///mitochondrial mRNA surveillance+++GO:0000958///mitochondrial mRNA catabolic process+++GO:0000962///positive regulation of mitochondrial RNA catabolic process+++GO:0043066///negative regulation of apoptotic process+++GO:0070584///mitochondrion morphogenesis+++GO:2000827///mitochondrial RNA surveillance+++GO:0006401///RNA catabolic process+++GO:0006310///DNA recombination","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001650///Helicase, C-terminal+++IPR022192///Mitochondrial degradasome RNA helicase subunit, C-terminal domain","[SUV3_HUMAN|Reviewed]RecName: Full=ATP-dependent RNA helicase SUPV3L1, mitochondrial; EC=3.6.4.13 {ECO:0000269|PubMed:12466530}; AltName: Full=Suppressor of var1 3-like protein 1; Short=SUV3-like protein 1; Flags: Precursor;+++[B1AR60_HUMAN|Unreviewed]SubName: Full=ATP-dependent RNA helicase SUPV3L1, mitochondrial {ECO:0000313|Ensembl:ENSP00000409072}; Flags: Fragment;+++[B7Z611_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50848, highly similar to Homo sapiens suppressor of var1, 3-like 1 (S. cerevisiae) (SUPV3L1), mRNA {ECO:0000313|EMBL:BAH13097.1}; Flags: Fragment;"]
[6854,"'SYN2'",33,26,29.5,"05216///Thyroid cancer+++04152///AMPK signaling pathway+++05202///Transcriptional misregulation in cancer+++05200///Pathways in cancer+++04714///Thermogenesis+++04211///Longevity regulating pathway+++05016///Huntington's disease+++03320///PPAR signaling pathway+++04380///Osteoclast differentiation","H01649///Schizophrenia+++H00658///Syndromic X-linked mental retardation",null,null,"GO:0031201///SNARE complex+++GO:0045202///synapse+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0008021///synaptic vesicle+++GO:0043209///myelin sheath+++GO:0014069///postsynaptic density+++GO:0030672///synaptic vesicle membrane+++GO:0030054///cell junction","GO:0005524///ATP binding","GO:0007268///chemical synaptic transmission+++GO:0097091///synaptic vesicle clustering+++GO:0099504///synaptic vesicle cycle+++GO:0007269///neurotransmitter secretion","IPR019736///Synapsin, phosphorylation site+++IPR020898///Synapsin, ATP-binding domain+++IPR020897///Synapsin, pre-ATP-grasp domain+++IPR019735///Synapsin, conserved site+++IPR001359///Synapsin+++IPR013815///ATP-grasp fold, subdomain 1+++IPR028712///Synapsin-3+++IPR016185///Pre-ATP-grasp domain superfamily","[SYN2_HUMAN|Reviewed]RecName: Full=Synapsin-2; AltName: Full=Synapsin II;+++[A0A024R2F6_HUMAN|Unreviewed]SubName: Full=Synapsin II, isoform CRA_a {ECO:0000313|EMBL:EAW64121.1};+++[A0A087WW91_HUMAN|Unreviewed]SubName: Full=Synapsin-2 {ECO:0000313|Ensembl:ENSP00000480038}; Flags: Fragment;+++[B3KRB3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33967 fis, clone DFNES2000913, highly similar to Synapsin-2 {ECO:0000313|EMBL:BAG52325.1};+++[Q59GM1_HUMAN|Unreviewed]SubName: Full=Synapsin II isoform IIb variant {ECO:0000313|EMBL:BAD92325.1}; Flags: Fragment;+++[Q86VA8_HUMAN|Unreviewed]SubName: Full=Synapsin II {ECO:0000313|EMBL:AAH51307.1};"]
[6875,"'TAF4B'",28,34,31,"05168///Herpes simplex infection+++03022///Basal transcription factors+++05016///Huntington's disease","H01282///Spermatogenic failure",null,null,"GO:0005654///nucleoplasm+++GO:0005669///transcription factor TFIID complex+++GO:0001650///fibrillar center+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0051059///NF-kappaB binding+++GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0003713///transcription coactivator activity+++GO:0003700///DNA-binding transcription factor activity","GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0048477///oogenesis+++GO:0007283///spermatogenesis+++GO:0051123///RNA polymerase II preinitiation complex assembly+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006366///transcription by RNA polymerase II","IPR009072///Histone-fold+++IPR037249///TAFH/NHR1 domain superfamily+++IPR003894///TAFH/NHR1+++IPR007900///Transcription initiation factor TFIID component TAF4","[TAF4B_HUMAN|Reviewed]RecName: Full=Transcription initiation factor TFIID subunit 4B; AltName: Full=Transcription initiation factor TFIID 105 kDa subunit; Short=TAF(II)105; Short=TAFII-105; Short=TAFII105;+++[B4DYT3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59074, highly similar to Transcription initiation factor TFIID 105 kDa subunit {ECO:0000313|EMBL:BAG63845.1};+++[J3KTH2_HUMAN|Unreviewed]SubName: Full=HCG38478, isoform CRA_a {ECO:0000313|EMBL:EAX01217.1}; SubName: Full=Transcription initiation factor TFIID subunit 4B {ECO:0000313|Ensembl:ENSP00000462980};"]
[6890,"'TAP1'",2186,1936,2061,"05168///Herpes simplex infection+++02010///ABC transporters+++05163///Human cytomegalovirus infection+++05340///Primary immunodeficiency+++04145///Phagosome+++04612///Antigen processing and presentation","H00093///Combined immunodeficiencies (CIDs)+++H00984///Bare lymphocyte syndrome (BLS) type1",null,null,"GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0042825///TAP complex+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0030670///phagocytic vesicle membrane+++GO:0005815///microtubule organizing center","GO:0042288///MHC class I protein binding+++GO:0043531///ADP binding+++GO:0042803///protein homodimerization activity+++GO:0046979///TAP2 binding+++GO:1904680///peptide transmembrane transporter activity+++GO:0046978///TAP1 binding+++GO:0005524///ATP binding+++GO:0042605///peptide antigen binding+++GO:0023029///MHC class Ib protein binding+++GO:0015433///peptide antigen-transporting ATPase activity","GO:0002474///antigen processing and presentation of peptide antigen via MHC class I+++GO:0015031///protein transport+++GO:0002250///adaptive immune response+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0006952///defense response+++GO:0015833///peptide transport+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0016032///viral process+++GO:0019885///antigen processing and presentation of endogenous peptide antigen via MHC class I+++GO:0046967///cytosol to ER transport","IPR039421///Type I protein exporter+++IPR017871///ABC transporter, conserved site+++IPR013305///ABC transporter Tap-like+++IPR036640///ABC transporter type 1, transmembrane domain superfamily+++IPR013306///Antigen peptide transporter 1+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003439///ABC transporter-like+++IPR003593///AAA+ ATPase domain+++IPR011527///ABC transporter type 1, transmembrane domain","[TAP1_HUMAN|Reviewed]RecName: Full=Antigen peptide transporter 1; Short=APT1; AltName: Full=ATP-binding cassette sub-family B member 2; AltName: Full=Peptide supply factor 1; AltName: Full=Peptide transporter PSF1; Short=PSF-1; AltName: Full=Peptide transporter TAP1; AltName: Full=Peptide transporter involved in antigen processing 1; AltName: Full=Really interesting new gene 4 protein;+++[A0A0S2Z5A6_HUMAN|Unreviewed]SubName: Full=TAP1 {ECO:0000313|EMBL:ARB08462.1}; SubName: Full=Transporter 1 ATP-binding cassette sub-family B isoform 1 {ECO:0000313|EMBL:ALQ33804.1}; Flags: Fragment;+++[B7Z7P4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53627, highly similar to Antigen peptide transporter 1 {ECO:0000313|EMBL:BAH13680.1};+++[O94774_HUMAN|Unreviewed]SubName: Full=TAP1N {ECO:0000313|EMBL:BAA32813.1};+++[Q9UEE1_HUMAN|Unreviewed]SubName: Full=TAP1N {ECO:0000313|EMBL:BAA32814.1}; Flags: Fragment;"]
[6909,"'TBX2'",24,40,32,"04013///MAPK signaling pathway - fly",{"$nulls":3},"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0035909///aorta morphogenesis+++GO:0007219///Notch signaling pathway+++GO:0048738///cardiac muscle tissue development+++GO:1901211///negative regulation of cardiac chamber formation+++GO:0003256///regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation+++GO:0035050///embryonic heart tube development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0042733///embryonic digit morphogenesis+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0036302///atrioventricular canal development+++GO:0090398///cellular senescence+++GO:0003148///outflow tract septum morphogenesis+++GO:0048596///embryonic camera-type eye morphogenesis+++GO:0001947///heart looping+++GO:0060465///pharynx development+++GO:0008016///regulation of heart contraction+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0008284///positive regulation of cell proliferation+++GO:0007275///multicellular organism development+++GO:0003007///heart morphogenesis+++GO:0060596///mammary placode formation+++GO:0060021///roof of mouth development+++GO:0003151///outflow tract morphogenesis+++GO:0007569///cell aging+++GO:0003203///endocardial cushion morphogenesis+++GO:1901208///negative regulation of heart looping+++GO:0060560///developmental growth involved in morphogenesis+++GO:0007521///muscle cell fate determination","IPR001699///Transcription factor, T-box+++IPR002070///Transcription factor, Brachyury+++IPR008967///p53-like transcription factor, DNA-binding+++IPR036960///T-box superfamily+++IPR022582///Transcription factor, T-box, region of unknown function+++IPR018186///Transcription factor, T-box, conserved site","[TBX2_HUMAN|Reviewed]RecName: Full=T-box transcription factor TBX2; Short=T-box protein 2;+++[A0A024QZ86_HUMAN|Unreviewed]SubName: Full=T-box 2, isoform CRA_a {ECO:0000313|EMBL:EAW51425.1};+++[F8WCM9_HUMAN|Unreviewed]SubName: Full=T-box transcription factor TBX2 {ECO:0000313|Ensembl:ENSP00000404781};"]
[6932,"'TCF7'",478.9,520.95,499.925,"05213///Endometrial cancer+++04916///Melanogenesis+++04934///Cushing's syndrome+++05221///Acute myeloid leukemia+++04390///Hippo signaling pathway+++05215///Prostate cancer+++05200///Pathways in cancer+++04520///Adherens junction+++05224///Breast cancer+++05217///Basal cell carcinoma+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++05210///Colorectal cancer+++04310///Wnt signaling pathway+++05216///Thyroid cancer+++05165///Human papillomavirus infection+++05225///Hepatocellular carcinoma+++05226///Gastric cancer",null,"M00677///Wnt signaling",null,"GO:0005654///nucleoplasm+++GO:0005667///transcription factor complex+++GO:0016604///nuclear body+++GO:0005719///nuclear euchromatin+++GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008013///beta-catenin binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0046632///alpha-beta T cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042127///regulation of cell proliferation+++GO:0033153///T cell receptor V(D)J recombination+++GO:0030538///embryonic genitalia morphogenesis+++GO:0048557///embryonic digestive tract morphogenesis+++GO:1904837///beta-catenin-TCF complex assembly+++GO:0048619///embryonic hindgut morphogenesis+++GO:0044336///canonical Wnt signaling pathway involved in negative regulation of apoptotic process+++GO:0021915///neural tube development+++GO:0071353///cellular response to interleukin-4+++GO:0016055///Wnt signaling pathway+++GO:0006955///immune response+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060070///canonical Wnt signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR036910///High mobility group box domain superfamily+++IPR024940///Transcription factor TCF/LEF+++IPR028785///Transcription factor 7+++IPR027397///Catenin binding domain superfamily+++IPR013558///CTNNB1 binding, N-teminal+++IPR009071///High mobility group box domain","[TCF7_HUMAN|Reviewed]RecName: Full=Transcription factor 7; Short=TCF-7; AltName: Full=T-cell-specific transcription factor 1; Short=T-cell factor 1; Short=TCF-1;+++[B3KQ75_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33018 fis, clone THYMU1000459, highly similar to Homo sapiens transcription factor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 5, mRNA {ECO:0000313|EMBL:BAG51937.1};+++[B7WNT5_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 (T-cell specific, HMG-box), isoform CRA_c {ECO:0000313|EMBL:EAW62279.1};+++[E5RG34_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000427870}; Flags: Fragment;+++[E5RG75_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000427782}; Flags: Fragment;+++[E5RGJ5_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000427758};+++[E5RGQ1_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000429946}; Flags: Fragment;+++[E5RHL1_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000429696}; Flags: Fragment;+++[E5RJ51_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000430617}; Flags: Fragment;+++[H0YAR8_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000427968}; Flags: Fragment;+++[H0YBC8_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000429178}; Flags: Fragment;+++[H0YBM1_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000429817}; Flags: Fragment;+++[H0YBP2_HUMAN|Unreviewed]SubName: Full=Transcription factor 7 {ECO:0000313|Ensembl:ENSP00000429935}; Flags: Fragment;"]
[6975,"'TECTB'",0,1,0.5,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0031225///anchored component of membrane+++GO:0016020///membrane","GO:0005201///extracellular matrix structural constituent",null,"IPR017977///Zona pellucida domain, conserved site+++IPR001507///Zona pellucida domain","[TECTB_HUMAN|Reviewed]RecName: Full=Beta-tectorin; Flags: Precursor;+++[A0A2R8Y6R9_HUMAN|Unreviewed]SubName: Full=Beta-tectorin {ECO:0000313|Ensembl:ENSP00000495514};+++[A0A2R8YGB5_HUMAN|Unreviewed]SubName: Full=Beta-tectorin {ECO:0000313|Ensembl:ENSP00000495832};"]
[7008,"'TEF'",126,183,154.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003690///double-stranded DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding","GO:0048511///rhythmic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR004827///Basic-leucine zipper domain+++IPR029832///Thyrotroph embryonic factor","[TEF_HUMAN|Reviewed]RecName: Full=Thyrotroph embryonic factor;+++[E0ZS57_HUMAN|Unreviewed]SubName: Full=Thyrotrophic embryonic factor {ECO:0000313|EMBL:ADM86749.1}; Flags: Fragment;+++[H0Y797_HUMAN|Unreviewed]SubName: Full=Thyrotroph embryonic factor {ECO:0000313|Ensembl:ENSP00000411170}; Flags: Fragment;+++[L8E7U2_HUMAN|Unreviewed]SubName: Full=Alternative protein TEF {ECO:0000313|EMBL:CCQ43209.1};"]
[7029,"'TFDP2'",791.86,753.36,772.61,"04110///Cell cycle",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005667///transcription factor complex+++GO:0005739///mitochondrion","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0008134///transcription factor binding+++GO:0003712///transcription coregulator activity+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:1903506///regulation of nucleic acid-templated transcription+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0007049///cell cycle+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0000278///mitotic cell cycle+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007507///heart development","IPR015648///Transcription factor DP+++IPR014889///Transcription factor DP, C-terminal+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR003316///E2F/DP family, winged-helix DNA-binding domain+++IPR028314///Transcription factor DP2+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR038168///Transcription factor DP, C-terminal domain superfamily+++IPR037241///E2F-DP heterodimerization region","[TFDP2_HUMAN|Reviewed]RecName: Full=Transcription factor Dp-2; AltName: Full=E2F dimerization partner 2;+++[C9J461_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417220}; Flags: Fragment;+++[C9J5D5_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417108}; Flags: Fragment;+++[C9J872_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417726}; Flags: Fragment;+++[C9J977_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000418122}; Flags: Fragment;+++[C9JCY5_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000420657}; Flags: Fragment;+++[C9JNB6_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000420456}; Flags: Fragment;+++[C9JTZ9_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000419540}; Flags: Fragment;+++[F8WAY9_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000417384};+++[H7C5C2_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000419507}; Flags: Fragment;+++[R4GN09_HUMAN|Unreviewed]SubName: Full=Transcription factor Dp-2 {ECO:0000313|Ensembl:ENSP00000473436}; Flags: Fragment;"]
[7049,"'TGFBR3'",135,113,124,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0034673///inhibin-betaglycan-ActRII complex+++GO:0031012///extracellular matrix+++GO:0009897///external side of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005576///extracellular region+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0005615///extracellular space+++GO:0005737///cytoplasm","GO:0015026///coreceptor activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0050431///transforming growth factor beta binding+++GO:0005114///type II transforming growth factor beta receptor binding+++GO:0005539///glycosaminoglycan binding+++GO:0005515///protein binding+++GO:0017134///fibroblast growth factor binding+++GO:0070123///transforming growth factor beta receptor activity, type III+++GO:0005024///transforming growth factor beta-activated receptor activity+++GO:0048185///activin binding+++GO:0030165///PDZ domain binding+++GO:0046332///SMAD binding+++GO:0008201///heparin binding","GO:0060038///cardiac muscle cell proliferation+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0051271///negative regulation of cellular component movement+++GO:0032354///response to follicle-stimulating hormone+++GO:0006955///immune response+++GO:0060979///vasculogenesis involved in coronary vascular morphogenesis+++GO:0003151///outflow tract morphogenesis+++GO:0001666///response to hypoxia+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0055010///ventricular cardiac muscle tissue morphogenesis+++GO:0030511///positive regulation of transforming growth factor beta receptor signaling pathway+++GO:0001837///epithelial to mesenchymal transition+++GO:0065003///protein-containing complex assembly+++GO:0060939///epicardium-derived cardiac fibroblast cell development+++GO:0030509///BMP signaling pathway+++GO:0060045///positive regulation of cardiac muscle cell proliferation+++GO:0060317///cardiac epithelial to mesenchymal transition+++GO:0060318///definitive erythrocyte differentiation+++GO:0016477///cell migration+++GO:0003007///heart morphogenesis+++GO:0060347///heart trabecula formation+++GO:0035556///intracellular signal transduction+++GO:0034699///response to luteinizing hormone+++GO:0046328///regulation of JNK cascade+++GO:0007181///transforming growth factor beta receptor complex assembly+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0003223///ventricular compact myocardium morphogenesis+++GO:0061384///heart trabecula morphogenesis+++GO:0043393///regulation of protein binding+++GO:0060216///definitive hemopoiesis+++GO:0034695///response to prostaglandin E+++GO:0062009///secondary palate development+++GO:0003150///muscular septum morphogenesis+++GO:0070372///regulation of ERK1 and ERK2 cascade+++GO:0031100///animal organ regeneration+++GO:0001889///liver development+++GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0060412///ventricular septum morphogenesis","IPR017977///Zona pellucida domain, conserved site+++IPR001507///Zona pellucida domain","[TGBR3_HUMAN|Reviewed]RecName: Full=Transforming growth factor beta receptor type 3; Short=TGF-beta receptor type 3; Short=TGFR-3; AltName: Full=Betaglycan; AltName: Full=Transforming growth factor beta receptor III; Short=TGF-beta receptor type III; Flags: Precursor;+++[A0A0A8KWK3_HUMAN|Unreviewed]SubName: Full=Transforming growth factor, beta receptor III {ECO:0000313|EMBL:CDJ98540.1}; SubName: Full=Transforming growth factor, beta receptor III (Betaglycan, 300kDa), isoform CRA_b {ECO:0000313|EMBL:EAW73113.1};+++[E9PAW7_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta receptor type 3 {ECO:0000313|Ensembl:ENSP00000395975}; Flags: Fragment;+++[E9PKY4_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta receptor type 3 {ECO:0000313|Ensembl:ENSP00000433477};+++[E9PMG7_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta receptor type 3 {ECO:0000313|Ensembl:ENSP00000434994};"]
[7070,"'THY1'",10639,15789,13214,"04670///Leukocyte transendothelial migration",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0030673///axolemma+++GO:0005575///cellular_component+++GO:0009986///cell surface+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0016324///apical plasma membrane+++GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0009897///external side of plasma membrane+++GO:0030425///dendrite+++GO:0043209///myelin sheath+++GO:0031362///anchored component of external side of plasma membrane+++GO:0046658///anchored component of plasma membrane+++GO:0032809///neuronal cell body membrane+++GO:0005576///extracellular region+++GO:0030426///growth cone+++GO:0031225///anchored component of membrane+++GO:0045121///membrane raft+++GO:0032590///dendrite membrane+++GO:0005829///cytosol","GO:0019901///protein kinase binding+++GO:0005096///GTPase activator activity+++GO:0005178///integrin binding+++GO:0005515///protein binding+++GO:0019899///enzyme binding+++GO:0003674///molecular_function+++GO:0034235///GPI anchor binding","GO:0050860///negative regulation of T cell receptor signaling pathway+++GO:0050852///T cell receptor signaling pathway+++GO:0001525///angiogenesis+++GO:0007155///cell adhesion+++GO:0070571///negative regulation of neuron projection regeneration+++GO:0061099///negative regulation of protein tyrosine kinase activity+++GO:0050771///negative regulation of axonogenesis+++GO:0001952///regulation of cell-matrix adhesion+++GO:0030336///negative regulation of cell migration+++GO:0043113///receptor clustering+++GO:0034116///positive regulation of heterotypic cell-cell adhesion+++GO:0051281///positive regulation of release of sequestered calcium ion into cytosol+++GO:0046549///retinal cone cell development+++GO:0007229///integrin-mediated signaling pathway+++GO:0006469///negative regulation of protein kinase activity+++GO:0048041///focal adhesion assembly+++GO:0050870///positive regulation of T cell activation+++GO:0046777///protein autophosphorylation+++GO:0043547///positive regulation of GTPase activity+++GO:2000298///regulation of Rho-dependent protein serine/threonine kinase activity+++GO:0007010///cytoskeleton organization+++GO:0002693///positive regulation of cellular extravasation+++GO:0051894///positive regulation of focal adhesion assembly+++GO:0007267///cell-cell signaling+++GO:0030334///regulation of cell migration+++GO:0008150///biological_process+++GO:0098609///cell-cell adhesion","IPR033292///Thy-1 membrane glycoprotein+++IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013106///Immunoglobulin V-set domain+++IPR013151///Immunoglobulin","[THY1_HUMAN|Reviewed]RecName: Full=Thy-1 membrane glycoprotein; AltName: Full=CDw90; AltName: Full=Thy-1 antigen; AltName: CD_antigen=CD90; Flags: Precursor;+++[B0YJA4_HUMAN|Unreviewed]SubName: Full=Thy-1 cell surface antigen, isoform CRA_a {ECO:0000313|EMBL:EAW67488.1}; SubName: Full=Thy-1 membrane glycoprotein variant 2 {ECO:0000313|EMBL:ACA06081.1}; SubName: Full=cDNA FLJ33325 fis, clone BNGH42008832, highly similar to THY-1 MEMBRANE GLYCOPROTEIN {ECO:0000313|EMBL:BAG52205.1}; SubName: Full=cDNA FLJ33677 fis, clone BRAWH2002125, highly similar to THY-1 MEMBRANE GLYCOPROTEIN {ECO:0000313|EMBL:BAG52259.1};+++[E9PIE1_HUMAN|Unreviewed]SubName: Full=Thy-1 membrane glycoprotein {ECO:0000313|Ensembl:ENSP00000432051};+++[E9PIM6_HUMAN|Unreviewed]SubName: Full=Thy-1 membrane glycoprotein {ECO:0000313|Ensembl:ENSP00000435753}; Flags: Fragment;+++[E9PNQ8_HUMAN|Unreviewed]SubName: Full=Thy-1 membrane glycoprotein {ECO:0000313|Ensembl:ENSP00000432808}; Flags: Fragment;+++[J3QRJ3_HUMAN|Unreviewed]SubName: Full=Thy-1 membrane glycoprotein {ECO:0000313|Ensembl:ENSP00000464248};+++[Q9HBB0_HUMAN|Unreviewed]SubName: Full=Thy-1 co-transcribed protein {ECO:0000313|EMBL:AAG13905.1}; SubName: Full=Thy-1 membrane glycoprotein variant 1 {ECO:0000313|EMBL:ACA06082.1}; SubName: Full=cDNA, FLJ94676, Homo sapiens Thy-1 co-transcribed (LOC94105), mRNA {ECO:0000313|EMBL:BAG36729.1};"]
[7087,"'ICAM5'",14,9,11.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0005515///protein binding+++GO:0005178///integrin binding","GO:0006909///phagocytosis+++GO:0098609///cell-cell adhesion+++GO:0030198///extracellular matrix organization+++GO:0050776///regulation of immune response+++GO:0007155///cell adhesion","IPR003987///Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal+++IPR003988///Intercellular adhesion molecule+++IPR013768///Intercellular adhesion molecule, N-terminal+++IPR003599///Immunoglobulin subtype+++IPR003598///Immunoglobulin subtype 2+++IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily","[ICAM5_HUMAN|Reviewed]RecName: Full=Intercellular adhesion molecule 5; Short=ICAM-5; AltName: Full=Telencephalin; Flags: Precursor;+++[K7EIL3_HUMAN|Unreviewed]SubName: Full=Intercellular adhesion molecule 5 {ECO:0000313|Ensembl:ENSP00000464796}; Flags: Fragment;+++[Q8N6I2_HUMAN|Unreviewed]SubName: Full=ICAM5 protein {ECO:0000313|EMBL:AAH30132.2}; Flags: Fragment;+++[Q8TAM9_HUMAN|Unreviewed]SubName: Full=Intercellular adhesion molecule 5, telencephalin {ECO:0000313|EMBL:AAH26338.1};"]
[7100,"'TLR5'",12,9,10.5,"05130///Pathogenic Escherichia coli infection+++05134///Legionellosis+++05132///Salmonella infection+++05321///Inflammatory bowel disease (IBD)+++04620///Toll-like receptor signaling pathway","H00080///Systemic lupus erythematosus",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0005149///interleukin-1 receptor binding","GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0071222///cellular response to lipopolysaccharide+++GO:0008584///male gonad development+++GO:0001819///positive regulation of cytokine production+++GO:0034146///toll-like receptor 5 signaling pathway+++GO:0007165///signal transduction+++GO:0050707///regulation of cytokine secretion+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0034123///positive regulation of toll-like receptor signaling pathway+++GO:0071260///cellular response to mechanical stimulus+++GO:0042742///defense response to bacterium+++GO:0006954///inflammatory response+++GO:0032757///positive regulation of interleukin-8 production+++GO:0002376///immune system process+++GO:0045087///innate immune response","IPR000483///Cysteine-rich flanking region, C-terminal+++IPR000157///Toll/interleukin-1 receptor homology (TIR) domain+++IPR032675///Leucine-rich repeat domain superfamily+++IPR003591///Leucine-rich repeat, typical subtype+++IPR001611///Leucine-rich repeat+++IPR027176///Toll-like receptor 5+++IPR035897///Toll/interleukin-1 receptor homology (TIR) domain superfamily","[TLR5_HUMAN|Reviewed]RecName: Full=Toll-like receptor 5; AltName: Full=Toll/interleukin-1 receptor-like protein 3; Flags: Precursor;+++[A0A2R8Y4Q2_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|Ensembl:ENSP00000493892}; Flags: Fragment;+++[A0A2R8Y7Z4_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|Ensembl:ENSP00000496355};+++[B1AZ06_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|Ensembl:ENSP00000385458}; Flags: Fragment;+++[B9VJ61_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69017.1};+++[B9VJ65_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69021.1};+++[B9VJ68_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69024.1};+++[B9VJ69_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69025.1};+++[B9VJ70_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69026.1};+++[B9VJ72_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69028.1};+++[B9VJ73_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69029.1};+++[B9VJ75_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69031.1};+++[B9VJ77_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:ACM69033.1};+++[D1CS79_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17462.1};+++[D1CS82_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17465.1};+++[D1CS83_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17466.1};+++[D1CS84_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17467.1};+++[D1CS85_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17468.1};+++[D1CS87_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17470.1};+++[D1CS88_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17471.1};+++[D1CS89_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17472.1};+++[D1CS90_HUMAN|Unreviewed]SubName: Full=Toll-like receptor 5 {ECO:0000313|EMBL:AAZ17473.1};"]
[7127,"'TNFAIP2'",193,146,169.5,{"$nulls":4},"GO:0000145///exocyst+++GO:0005615///extracellular space","GO:0000149///SNARE binding","GO:0006887///exocytosis+++GO:0007275///multicellular organism development+++GO:0001525///angiogenesis+++GO:0030154///cell differentiation+++GO:0051601///exocyst localization","IPR010326///Exocyst complex component EXOC3/Sec6","[TNAP2_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor alpha-induced protein 2; Short=TNF alpha-induced protein 2; AltName: Full=Primary response gene B94 protein;+++[A1A584_HUMAN|Unreviewed]SubName: Full=TNFAIP2 protein {ECO:0000313|EMBL:AAI28450.1};+++[H0YKI8_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 2 {ECO:0000313|Ensembl:ENSP00000452824};+++[H0YKR7_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 2 {ECO:0000313|Ensembl:ENSP00000452914}; Flags: Fragment;+++[H0YKY9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 2 {ECO:0000313|Ensembl:ENSP00000452992};+++[H0YL88_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 2 {ECO:0000313|Ensembl:ENSP00000453103}; Flags: Fragment;+++[H0YLC0_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 2 {ECO:0000313|Ensembl:ENSP00000453142}; Flags: Fragment;+++[H0YM45_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor alpha-induced protein 2 {ECO:0000313|Ensembl:ENSP00000453458}; Flags: Fragment;"]
[7153,"'TOP2A'",2,1,1.5,"01524///Platinum drug resistance",{"$nulls":3},"GO:0005730///nucleolus+++GO:0019035///viral integration complex+++GO:0032991///protein-containing complex+++GO:0000228///nuclear chromosome+++GO:0005634///nucleus+++GO:0009330///DNA topoisomerase complex (ATP-hydrolyzing)+++GO:0005814///centriole+++GO:0005654///nucleoplasm+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0000793///condensed chromosome","GO:0005524///ATP binding+++GO:0005080///protein kinase C binding+++GO:0008144///drug binding+++GO:0003677///DNA binding+++GO:0003682///chromatin binding+++GO:0003723///RNA binding+++GO:0000287///magnesium ion binding+++GO:0042826///histone deacetylase binding+++GO:0008301///DNA binding, bending+++GO:0061505///DNA topoisomerase II activity+++GO:0042803///protein homodimerization activity+++GO:0008022///protein C-terminus binding+++GO:0003916///DNA topoisomerase activity+++GO:0000166///nucleotide binding+++GO:0008094///DNA-dependent ATPase activity+++GO:0043130///ubiquitin binding+++GO:0046982///protein heterodimerization activity+++GO:0046872///metal ion binding+++GO:0019899///enzyme binding+++GO:0016853///isomerase activity+++GO:0003918///DNA topoisomerase type II (ATP-hydrolyzing) activity+++GO:0005515///protein binding","GO:0006265///DNA topological change+++GO:0048511///rhythmic process+++GO:0040016///embryonic cleavage+++GO:0007059///chromosome segregation+++GO:0006259///DNA metabolic process+++GO:0000819///sister chromatid segregation+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0042752///regulation of circadian rhythm+++GO:0030261///chromosome condensation+++GO:0043065///positive regulation of apoptotic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006266///DNA ligation+++GO:0007143///female meiotic nuclear division+++GO:0030263///apoptotic chromosome condensation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045870///positive regulation of single stranded viral RNA replication via double stranded DNA intermediate+++GO:1905463///negative regulation of DNA duplex unwinding+++GO:0044774///mitotic DNA integrity checkpoint+++GO:0000712///resolution of meiotic recombination intermediates","IPR013759///DNA topoisomerase, type IIA, subunit B, C-terminal+++IPR013506///DNA topoisomerase, type IIA, subunit B, domain 2+++IPR002205///DNA topoisomerase, type IIA, subunit A/C-terminal+++IPR001241///DNA topoisomerase, type IIA+++IPR003594///Histidine kinase/HSP90-like ATPase+++IPR036890///Histidine kinase/HSP90-like ATPase superfamily+++IPR012542///DTHCT+++IPR013758///DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta+++IPR020568///Ribosomal protein S5 domain 2-type fold+++IPR034157///DNA topoisomerase 2, TOPRIM domain+++IPR018522///DNA topoisomerase, type IIA, conserved site+++IPR001154///DNA topoisomerase II, eukaryotic-type+++IPR006171///TOPRIM  domain+++IPR014721///Ribosomal protein S5 domain 2-type fold, subgroup+++IPR031660///C-terminal associated domain of TOPRIM+++IPR013760///DNA topoisomerase, type IIA-like domain superfamily","[TOP2A_HUMAN|Reviewed]RecName: Full=DNA topoisomerase 2-alpha; EC=5.99.1.3; AltName: Full=DNA topoisomerase II, alpha isozyme;+++[J3KTB7_HUMAN|Unreviewed]SubName: Full=DNA topoisomerase 2-alpha {ECO:0000313|Ensembl:ENSP00000462908}; Flags: Fragment;+++[J3QR57_HUMAN|Unreviewed]SubName: Full=DNA topoisomerase 2-alpha {ECO:0000313|Ensembl:ENSP00000464055}; Flags: Fragment;"]
[7169,"'TPM2'",25867,18482,22174.5,"05410///Hypertrophic cardiomyopathy (HCM)+++05414///Dilated cardiomyopathy (DCM)+++04261///Adrenergic signaling in cardiomyocytes+++04260///Cardiac muscle contraction","H00698///Nemaline myopathy+++H00811///Distal arthrogryposis (DA)+++H00702///Cap myopathy",null,null,"GO:0005737///cytoplasm+++GO:0005862///muscle thin filament tropomyosin+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0015629///actin cytoskeleton+++GO:0005884///actin filament","GO:0008307///structural constituent of muscle+++GO:0051015///actin filament binding+++GO:0003779///actin binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0042802///identical protein binding","GO:0030049///muscle filament sliding+++GO:0006936///muscle contraction+++GO:0043462///regulation of ATPase activity+++GO:0007015///actin filament organization","IPR000533///Tropomyosin","[TPM2_HUMAN|Reviewed]RecName: Full=Tropomyosin beta chain; AltName: Full=Beta-tropomyosin; AltName: Full=Tropomyosin-2;+++[A0A2R8Y6A3_HUMAN|Unreviewed]SubName: Full=Tropomyosin beta chain {ECO:0000313|Ensembl:ENSP00000495075}; Flags: Fragment;+++[A7XZE4_HUMAN|Unreviewed]SubName: Full=Beta tropomyosin isoform {ECO:0000313|EMBL:ABU62930.1}; SubName: Full=Tropomyosin beta chain {ECO:0000313|Ensembl:ENSP00000495440};+++[D3DRP0_HUMAN|Unreviewed]SubName: Full=Tropomyosin 2 (Beta), isoform CRA_c {ECO:0000313|EMBL:EAW58357.1};+++[Q5TCU3_HUMAN|Unreviewed]SubName: Full=Tropomyosin beta chain {ECO:0000313|Ensembl:ENSP00000367541};+++[Q5TCU8_HUMAN|Unreviewed]SubName: Full=Tropomyosin beta chain {ECO:0000313|Ensembl:ENSP00000367550};+++[U3KQK2_HUMAN|Unreviewed]SubName: Full=Tropomyosin beta chain {ECO:0000313|Ensembl:ENSP00000475952}; Flags: Fragment;+++[V9HW25_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 273 {ECO:0000313|EMBL:ACI45996.1};"]
[7189,"'TRAF6'",385,406,395.5,"04120///Ubiquitin mediated proteolysis+++05169///Epstein-Barr virus infection+++05142///Chagas disease (American trypanosomiasis)+++04380///Osteoclast differentiation+++04620///Toll-like receptor signaling pathway+++05162///Measles+++04013///MAPK signaling pathway - fly+++04010///MAPK signaling pathway+++05140///Leishmaniasis+++04722///Neurotrophin signaling pathway+++05133///Pertussis+++04657///IL-17 signaling pathway+++05222///Small cell lung cancer+++05145///Toxoplasmosis+++05160///Hepatitis C+++04144///Endocytosis+++04140///Autophagy - animal+++05152///Tuberculosis+++05168///Herpes simplex infection+++04214///Apoptosis - fly+++04622///RIG-I-like receptor signaling pathway+++04621///NOD-like receptor signaling pathway+++04064///NF-kappa B signaling pathway+++05200///Pathways in cancer",null,"M00686///Toll-like receptor signaling",null,"GO:0035631///CD40 receptor complex+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005938///cell cortex+++GO:0010008///endosome membrane+++GO:0005811///lipid droplet+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005737///cytoplasm","GO:0031625///ubiquitin protein ligase binding+++GO:0008270///zinc ion binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031996///thioesterase binding+++GO:0047485///protein N-terminus binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0042826///histone deacetylase binding+++GO:0043422///protein kinase B binding+++GO:0005164///tumor necrosis factor receptor binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0006955///immune response+++GO:0009887///animal organ morphogenesis+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0042102///positive regulation of T cell proliferation+++GO:0016567///protein ubiquitination+++GO:0042981///regulation of apoptotic process+++GO:0031666///positive regulation of lipopolysaccharide-mediated signaling pathway+++GO:0045672///positive regulation of osteoclast differentiation+++GO:0000209///protein polyubiquitination+++GO:0001503///ossification+++GO:0007254///JNK cascade+++GO:0051023///regulation of immunoglobulin secretion+++GO:0034162///toll-like receptor 9 signaling pathway+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0032743///positive regulation of interleukin-2 production+++GO:0032147///activation of protein kinase activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0042088///T-helper 1 type immune response+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071345///cellular response to cytokine stimulus+++GO:0019221///cytokine-mediated signaling pathway+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0006974///cellular response to DNA damage stimulus+++GO:0002726///positive regulation of T cell cytokine production+++GO:0043066///negative regulation of apoptotic process+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0051865///protein autoubiquitination+++GO:0007165///signal transduction+++GO:0002376///immune system process+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0045084///positive regulation of interleukin-12 biosynthetic process+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0001843///neural tube closure+++GO:0048468///cell development+++GO:0043011///myeloid dendritic cell differentiation+++GO:0043065///positive regulation of apoptotic process+++GO:0043507///positive regulation of JUN kinase activity+++GO:0031293///membrane protein intracellular domain proteolysis+++GO:0043122///regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0030316///osteoclast differentiation+++GO:0045453///bone resorption+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0031398///positive regulation of protein ubiquitination+++GO:0045410///positive regulation of interleukin-6 biosynthetic process+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0071222///cellular response to lipopolysaccharide+++GO:1904996///positive regulation of leukocyte adhesion to vascular endothelial cell+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0002224///toll-like receptor signaling pathway+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:2000679///positive regulation of transcription regulatory region DNA binding+++GO:0000187///activation of MAPK activity+++GO:0070555///response to interleukin-1+++GO:0050852///T cell receptor signaling pathway+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0016579///protein deubiquitination+++GO:0046849///bone remodeling+++GO:0070534///protein K63-linked ubiquitination","IPR027139///TNF receptor-associated factor 6+++IPR008974///TRAF-like+++IPR017907///Zinc finger, RING-type, conserved site+++IPR001293///Zinc finger, TRAF-type+++IPR012227///TNF receptor-associated factor TRAF+++IPR001841///Zinc finger, RING-type+++IPR037309///TNF receptor-associated factor 6, MATH domain+++IPR002083///MATH/TRAF domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type","[TRAF6_HUMAN|Reviewed]RecName: Full=TNF receptor-associated factor 6; EC=2.3.2.27; AltName: Full=E3 ubiquitin-protein ligase TRAF6; AltName: Full=Interleukin-1 signal transducer; AltName: Full=RING finger protein 85; AltName: Full=RING-type E3 ubiquitin transferase TRAF6 {ECO:0000305};"]
[723790,"'HIST2H2AA4'",267,127.44,197.22,"04217///Necroptosis+++05322///Systemic lupus erythematosus+++05034///Alcoholism",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0046982///protein heterodimerization activity","GO:0006342///chromatin silencing","IPR032458///Histone H2A conserved site+++IPR009072///Histone-fold+++IPR002119///Histone H2A+++IPR032454///Histone H2A, C-terminal domain+++IPR007125///Histone H2A/H2B/H3","[H2A2A_HUMAN|Reviewed]RecName: Full=Histone H2A type 2-A; AltName: Full=Histone H2A.2; AltName: Full=Histone H2A/o;"]
[7268,"'TTC4'",286,250,268,{"$nulls":5},"GO:0005515///protein binding",null,"IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR019734///Tetratricopeptide repeat","[TTC4_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 4; Short=TPR repeat protein 4;"]
[727957,"'MROH1'",1125,1149,1137,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",{"$nulls":5},"IPR011989///Armadillo-like helical+++IPR016024///Armadillo-type fold+++IPR021133///HEAT, type 2+++IPR000357///HEAT repeat","[MROH1_HUMAN|Reviewed]RecName: Full=Maestro heat-like repeat-containing protein family member 1; AltName: Full=HEAT repeat-containing protein 7A;+++[B4DIR5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56026 {ECO:0000313|EMBL:BAG58577.1};+++[E9PHY8_HUMAN|Unreviewed]SubName: Full=Maestro heat-like repeat-containing protein family member 1 {ECO:0000313|Ensembl:ENSP00000436636};+++[Q96AG6_HUMAN|Unreviewed]SubName: Full=HEATR7A protein {ECO:0000313|EMBL:AAH17118.1}; Flags: Fragment;"]
[728294,"'D2HGDH'",141,227,184,null,"H01225///D-2-hydroxyglutaric aciduria (D-2-HGA)",null,null,"GO:0031234///extrinsic component of cytoplasmic side of plasma membrane+++GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0003824///catalytic activity+++GO:0004458///D-lactate dehydrogenase (cytochrome) activity+++GO:0071949///FAD binding+++GO:0050660///flavin adenine dinucleotide binding+++GO:0051990///(R)-2-hydroxyglutarate dehydrogenase activity+++GO:0016491///oxidoreductase activity","GO:0022904///respiratory electron transport chain+++GO:0010042///response to manganese ion+++GO:0032026///response to magnesium ion+++GO:0051592///response to calcium ion+++GO:0032025///response to cobalt ion+++GO:0044267///cellular protein metabolic process+++GO:0010043///response to zinc ion+++GO:0055114///oxidation-reduction process+++GO:0019516///lactate oxidation+++GO:0006103///2-oxoglutarate metabolic process","IPR016171///Vanillyl-alcohol oxidase, C-terminal subdomain 2+++IPR016164///FAD-linked oxidase-like, C-terminal+++IPR004113///FAD-linked oxidase, C-terminal+++IPR016169///FAD-binding, type PCMH, subdomain 2+++IPR006094///FAD linked oxidase, N-terminal+++IPR036318///FAD-binding, type PCMH-like superfamily+++IPR016166///FAD-binding domain, PCMH-type+++IPR016167///FAD-binding, type PCMH, subdomain 1","[D2HDH_HUMAN|Reviewed]RecName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial; EC=1.1.99.-; Flags: Precursor;+++[B3KSR6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ36830 fis, clone ASTRO2010582, highly similar to D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|EMBL:BAG52828.1};+++[B4E3K7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56310, highly similar to D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|EMBL:BAG65519.1};+++[B5MCV2_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000384723};+++[F8WCF9_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000400212};+++[G5E9E8_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, isoform CRA_b {ECO:0000313|EMBL:EAW71291.1}; SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000383580};+++[H7BZ32_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000387479}; Flags: Fragment;+++[H7C021_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000392602}; Flags: Fragment;+++[H7C0N1_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000395837}; Flags: Fragment;+++[H7C290_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000404596}; Flags: Fragment;+++[H7C3L2_HUMAN|Unreviewed]SubName: Full=D-2-hydroxyglutarate dehydrogenase, mitochondrial {ECO:0000313|Ensembl:ENSP00000412511}; Flags: Fragment;"]
[7286,"'TUFT1'",1818.95,1500.97,1659.96,"04140///Autophagy - animal+++03010///Ribosome+++04137///Mitophagy - animal","H00237///Diamond-Blackfan anemia (DBA)","M00177///Ribosome, eukaryotes",null,"GO:0005737///cytoplasm+++GO:0005576///extracellular region","GO:0005515///protein binding+++GO:0030345///structural constituent of tooth enamel","GO:0030282///bone mineralization+++GO:0035556///intracellular signal transduction+++GO:0042476///odontogenesis+++GO:0031214///biomineral tissue development","IPR024846///Tuftelin","[TUFT1_HUMAN|Reviewed]RecName: Full=Tuftelin;+++[A6PVU8_HUMAN|Unreviewed]SubName: Full=Tuftelin {ECO:0000313|Ensembl:ENSP00000376476};+++[B7Z4Y1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58031, highly similar to Tuftelin {ECO:0000313|EMBL:BAH12717.1};+++[Q6UWW7_HUMAN|Unreviewed]SubName: Full=TUFT1 {ECO:0000313|EMBL:AAQ88973.1}; SubName: Full=Tuftelin {ECO:0000313|Ensembl:ENSP00000343781};"]
[7289,"'TULP3'",536,553,544.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0097546///ciliary base+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005930///axoneme+++GO:0005929///cilium+++GO:0097731///9+0 non-motile cilium+++GO:0005730///nucleolus+++GO:0005576///extracellular region+++GO:0005737///cytoplasm","GO:0044877///protein-containing complex binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0019899///enzyme binding+++GO:0120160///intraciliary transport particle A binding+++GO:0035091///phosphatidylinositol binding+++GO:0005515///protein binding","GO:0021904///dorsal/ventral neural tube patterning+++GO:0042733///embryonic digit morphogenesis+++GO:0060831///smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0045879///negative regulation of smoothened signaling pathway+++GO:0061512///protein localization to cilium+++GO:0006355///regulation of transcription, DNA-templated+++GO:0060173///limb development+++GO:0061548///ganglion development+++GO:0097500///receptor localization to non-motile cilium+++GO:1901621///negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0007420///brain development+++GO:0001841///neural tube formation+++GO:0060348///bone development+++GO:0021914///negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0031076///embryonic camera-type eye development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:1903546///protein localization to photoreceptor outer segment+++GO:0001843///neural tube closure+++GO:0009952///anterior/posterior pattern specification+++GO:0021915///neural tube development+++GO:0008589///regulation of smoothened signaling pathway+++GO:0060434///bronchus morphogenesis+++GO:0021953///central nervous system neuron differentiation+++GO:0007275///multicellular organism development","IPR025659///Tubby-like, C-terminal+++IPR000007///Tubby, C-terminal+++IPR018066///Tubby, C-terminal, conserved site+++IPR005398///Tubby, N-terminal","[TULP3_HUMAN|Reviewed]RecName: Full=Tubby-related protein 3; AltName: Full=Tubby-like protein 3;+++[B7Z1E7_HUMAN|Unreviewed]RecName: Full=Tubby-like protein {ECO:0000256|RuleBase:RU361125};+++[F5GWL5_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000441599};+++[F5H7B9_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000442631}; Flags: Fragment;+++[H0YFU8_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000440364}; Flags: Fragment;+++[H0YG12_HUMAN|Unreviewed]SubName: Full=Tubby-related protein 3 {ECO:0000313|Ensembl:ENSP00000441319}; Flags: Fragment;"]
[729515,"'TMEM242'",197,223,210,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"IPR009792///Transmembrane protein 242","[TM242_HUMAN|Reviewed]RecName: Full=Transmembrane protein 242;+++[Q5T2S1_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 242 {ECO:0000313|Ensembl:ENSP00000356112};"]
[729991,"'BORCS8'",424.19,250.93,337.56,{"$nulls":4},"GO:0016020///membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0099078///BORC complex","GO:0005515///protein binding","GO:0007507///heart development","IPR019320///BLOC-1-related complex subunit 8","[BORC8_HUMAN|Reviewed]RecName: Full=BLOC-1-related complex subunit 8 {ECO:0000305}; AltName: Full=MEF2B neighbor {ECO:0000312|HGNC:HGNC:37247};+++[K7ENY0_HUMAN|Unreviewed]SubName: Full=BLOC-1-related complex subunit 8 {ECO:0000313|Ensembl:ENSP00000467140}; Flags: Fragment;+++[U3KPZ4_HUMAN|Unreviewed]SubName: Full=BLOC-1-related complex subunit 8 {ECO:0000313|Ensembl:ENSP00000475370};"]
[7311,"'UBA52'",9444,7016,8230,"03010///Ribosome",null,"M00179///Ribosome, archaea+++M00177///Ribosome, eukaryotes",null,"GO:0030666///endocytic vesicle membrane+++GO:0005840///ribosome+++GO:0005741///mitochondrial outer membrane+++GO:0005886///plasma membrane+++GO:0043657///host cell+++GO:0022627///cytosolic small ribosomal subunit+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005765///lysosomal membrane+++GO:0005783///endoplasmic reticulum+++GO:0031982///vesicle+++GO:0022625///cytosolic large ribosomal subunit+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0010008///endosome membrane+++GO:0070062///extracellular exosome+++GO:0005789///endoplasmic reticulum membrane","GO:0031625///ubiquitin protein ligase binding+++GO:0031386///protein tag+++GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding","GO:0043488///regulation of mRNA stability+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0019068///virion assembly+++GO:0000209///protein polyubiquitination+++GO:0043065///positive regulation of apoptotic process+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0016579///protein deubiquitination+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0075733///intracellular transport of virus+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0019985///translesion synthesis+++GO:0019058///viral life cycle+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0016567///protein ubiquitination+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0030512///negative regulation of transforming growth factor beta receptor signaling pathway+++GO:0006625///protein targeting to peroxisome+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0006464///cellular protein modification process+++GO:0042276///error-prone translesion synthesis+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000187///activation of MAPK activity+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0002755///MyD88-dependent toll-like receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0017085///response to insecticide+++GO:0006413///translational initiation+++GO:0016197///endosomal transport+++GO:0051403///stress-activated MAPK cascade+++GO:0016055///Wnt signaling pathway+++GO:0055085///transmembrane transport+++GO:0006614///SRP-dependent cotranslational protein targeting to membrane+++GO:0007254///JNK cascade+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0019941///modification-dependent protein catabolic process+++GO:0061024///membrane organization+++GO:0070987///error-free translesion synthesis+++GO:0070911///global genome nucleotide-excision repair+++GO:0044267///cellular protein metabolic process+++GO:0006412///translation+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0036297///interstrand cross-link repair+++GO:0019221///cytokine-mediated signaling pathway+++GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0043066///negative regulation of apoptotic process","IPR019956///Ubiquitin+++IPR029071///Ubiquitin-like domain superfamily+++IPR000626///Ubiquitin domain+++IPR038587///Ribosomal protein L40e superfamily+++IPR019954///Ubiquitin conserved site+++IPR001975///Ribosomal protein L40e","[RL40_HUMAN|Reviewed]RecName: Full=Ubiquitin-60S ribosomal protein L40; AltName: Full=CEP52; AltName: Full=Ubiquitin A-52 residue ribosomal protein fusion product 1; Contains: RecName: Full=Ubiquitin; Contains: RecName: Full=60S ribosomal protein L40; AltName: Full=Large ribosomal subunit protein eL40 {ECO:0000303|PubMed:24524803}; Flags: Precursor;+++[M0R1M6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-60S ribosomal protein L40 {ECO:0000313|Ensembl:ENSP00000471991}; Flags: Fragment;+++[M0R1V7_HUMAN|Unreviewed]SubName: Full=Ubiquitin-60S ribosomal protein L40 {ECO:0000313|Ensembl:ENSP00000472137}; Flags: Fragment;+++[M0R2S1_HUMAN|Unreviewed]SubName: Full=Ubiquitin-60S ribosomal protein L40 {ECO:0000313|Ensembl:ENSP00000472768}; Flags: Fragment;+++[Q3MIH3_HUMAN|Unreviewed]SubName: Full=Ubiquitin A-52 residue ribosomal protein fusion product 1 {ECO:0000313|EMBL:AAI01831.1}; SubName: Full=Ubiquitin A-52 residue ribosomal protein fusion product 1, isoform CRA_a {ECO:0000313|EMBL:EAW84715.1}; SubName: Full=cDNA, FLJ95576, Homo sapiens ubiquitin A-52 residue ribosomal protein fusionproduct 1 (UBA52), mRNA {ECO:0000313|EMBL:BAG37261.1};+++[Q7Z4P3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAP97731.1};"]
[733,"'C8G'",8,0,4,"05322///Systemic lupus erythematosus+++05146///Amoebiasis+++05020///Prion diseases+++04610///Complement and coagulation cascades","H00103///Late complement pathway defects",null,null,"GO:0072562///blood microparticle+++GO:0070062///extracellular exosome+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0005579///membrane attack complex","GO:0036094///small molecule binding+++GO:0019841///retinol binding+++GO:0001848///complement binding+++GO:0044877///protein-containing complex binding","GO:0006957///complement activation, alternative pathway+++GO:0019835///cytolysis+++GO:0002376///immune system process+++GO:0030449///regulation of complement activation+++GO:0006958///complement activation, classical pathway+++GO:0045087///innate immune response","IPR022272///Lipocalin family conserved site+++IPR002968///Alpha-1-microglobulin+++IPR002345///Lipocalin+++IPR000566///Lipocalin/cytosolic fatty-acid binding domain+++IPR012674///Calycin","[CO8G_HUMAN|Reviewed]RecName: Full=Complement component C8 gamma chain; Flags: Precursor;+++[Q5SQ08_HUMAN|Unreviewed]SubName: Full=Complement component C8 gamma chain {ECO:0000313|Ensembl:ENSP00000360697}; Flags: Fragment;"]
[7351,"'UCP2'",859,941,900,null,"H02106///Genetic obesity",null,null,"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0031966///mitochondrial membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0017077///oxidative phosphorylation uncoupler activity+++GO:0022857///transmembrane transporter activity","GO:0009409///response to cold+++GO:0043066///negative regulation of apoptotic process+++GO:0071333///cellular response to glucose stimulus+++GO:0000303///response to superoxide+++GO:1990845///adaptive thermogenesis+++GO:0010942///positive regulation of cell death+++GO:1990542///mitochondrial transmembrane transport+++GO:0032869///cellular response to insulin stimulus+++GO:0007565///female pregnancy+++GO:0001666///response to hypoxia+++GO:0051881///regulation of mitochondrial membrane potential+++GO:0009749///response to glucose+++GO:0032870///cellular response to hormone stimulus+++GO:0055085///transmembrane transport+++GO:0007568///aging+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0097421///liver regeneration+++GO:0070542///response to fatty acid+++GO:0006839///mitochondrial transport+++GO:0034198///cellular response to amino acid starvation+++GO:1902600///proton transmembrane transport+++GO:0061179///negative regulation of insulin secretion involved in cellular response to glucose stimulus","IPR040062///Mitochondrial carrier domain protein+++IPR023395///Mitochondrial carrier domain superfamily+++IPR018108///Mitochondrial substrate/solute carrier+++IPR002030///Mitochondrial carrier UCP-like","[UCP2_HUMAN|Reviewed]RecName: Full=Mitochondrial uncoupling protein 2; Short=UCP 2; AltName: Full=Solute carrier family 25 member 8; AltName: Full=UCPH;+++[A0A024R5N5_HUMAN|Unreviewed]SubName: Full=Uncoupling protein 2 (Mitochondrial, proton carrier), isoform CRA_a {ECO:0000313|EMBL:EAW74924.1};+++[F5GX45_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 2 {ECO:0000313|Ensembl:ENSP00000441147};+++[F5H312_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 2 {ECO:0000313|Ensembl:ENSP00000438230}; Flags: Fragment;+++[H0YFQ0_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 2 {ECO:0000313|Ensembl:ENSP00000439706}; Flags: Fragment;+++[H0YFR8_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 2 {ECO:0000313|Ensembl:ENSP00000439951}; Flags: Fragment;"]
[7378,"'UPP1'",47.01,45,46.005,"00983///Drug metabolism - other enzymes+++01100///Metabolic pathways+++00240///Pyrimidine metabolism",null,null,"R02484///deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase; deoxyuridine:orthophosphate   Deoxyuridine + Orthophosphate <=> Uracil + 2-Deoxy-D-ribose 1-phosphate+++R08229///5-fluorouridine:phosphate alpha-D-ribosyltransferase   5-FU + alpha-D-Ribose 1-phosphate <=> 5-Fluorouridine + Orthophosphate+++R01876///uridine:phosphate alpha-D-ribosyltransferase   Uridine + Orthophosphate <=> Uracil + alpha-D-Ribose 1-phosphate","GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0016757///transferase activity, transferring glycosyl groups+++GO:0004850///uridine phosphorylase activity+++GO:0016740///transferase activity+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0003824///catalytic activity","GO:0006218///uridine catabolic process+++GO:0043097///pyrimidine nucleoside salvage+++GO:0009116///nucleoside metabolic process+++GO:0006220///pyrimidine nucleotide metabolic process+++GO:0044206///UMP salvage+++GO:0046135///pyrimidine nucleoside catabolic process+++GO:0046108///uridine metabolic process+++GO:0042149///cellular response to glucose starvation+++GO:0009166///nucleotide catabolic process+++GO:0006139///nucleobase-containing compound metabolic process","IPR035994///Nucleoside phosphorylase superfamily+++IPR010059///Uridine phosphorylase, eukaryotic+++IPR000845///Nucleoside phosphorylase domain+++IPR018016///Nucleoside phosphorylase, conserved site","[UPP1_HUMAN|Reviewed]RecName: Full=Uridine phosphorylase 1; Short=UPase 1; Short=UrdPase 1; EC=2.4.2.3 {ECO:0000269|PubMed:7488099};+++[B4DND0_HUMAN|Unreviewed]SubName: Full=Uridine phosphorylase 1 {ECO:0000313|Ensembl:ENSP00000414963}; SubName: Full=cDNA FLJ60728, highly similar to Uridine phosphorylase 1 {ECO:0000313|EMBL:BAG60192.1};+++[C9J486_HUMAN|Unreviewed]SubName: Full=Uridine phosphorylase 1 {ECO:0000313|Ensembl:ENSP00000405209}; Flags: Fragment;+++[C9JIP2_HUMAN|Unreviewed]SubName: Full=Uridine phosphorylase 1 {ECO:0000313|Ensembl:ENSP00000390118}; Flags: Fragment;+++[C9K0J2_HUMAN|Unreviewed]SubName: Full=Uridine phosphorylase 1 {ECO:0000313|Ensembl:ENSP00000387607}; Flags: Fragment;+++[F8WD51_HUMAN|Unreviewed]SubName: Full=Uridine phosphorylase 1 {ECO:0000313|Ensembl:ENSP00000396820};+++[Q86Y75_HUMAN|Unreviewed]SubName: Full=UPP1 protein {ECO:0000313|EMBL:AAH47030.1};"]
[7404,"'UTY'",100,139,119.5,"05202///Transcriptional misregulation in cancer","H00570///Kabuki syndrome+++H01667///Medulloblastoma","M00340///Proteasome, 20S core particle+++M00337///Immunoproteasome",null,"GO:0005634///nucleus+++GO:0044666///MLL3/4 complex+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005575///cellular_component+++GO:0016021///integral component of membrane","GO:0003682///chromatin binding+++GO:0031490///chromatin DNA binding+++GO:0046872///metal ion binding+++GO:0032452///histone demethylase activity+++GO:0071558///histone demethylase activity (H3-K27 specific)+++GO:0016491///oxidoreductase activity+++GO:0051213///dioxygenase activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003674///molecular_function","GO:0055114///oxidation-reduction process+++GO:0071557///histone H3-K27 demethylation+++GO:0008150///biological_process+++GO:0006325///chromatin organization+++GO:0010468///regulation of gene expression","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR003347///JmjC domain+++IPR019734///Tetratricopeptide repeat+++IPR001440///Tetratricopeptide repeat 1+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR029516///Histone demethylase UTY",{"$cut":{"chars":32759,"head":"[UTY_HUMAN|Reviewed]RecName: Full=Histone demethylase UTY; EC=1.14.11.-; AltName: Full=Ubiquitously-transcribed TPR protein on the Y chromosome; AltName: Full=Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein;+++[A0A087X0Y2_HUMAN|Unreviewed]SubName: Full=Histone demethylase UTY {ECO:0000313|Ensembl:ENSP00000483735};+++[A0A087X248_HUMAN|Unreviewed]SubName: Full=Histone demethylase UTY {ECO:0000313|Ensembl:ENSP00000484698};+++[A0A087X2I9_HUMAN|Unreviewed]SubName: Full=Histone demethylase UTY {ECO:0000313|Ensembl:ENSP00000485013};+++[A0A096LPD8_HUMAN|Unreviewed]SubName: Full=Histone demethylase UTY {ECO:0000313|Ensembl:ENSP00000439922};+++[A6NCS7_HUMAN|Unreviewed]SubName: Full=Histone demethylase UTY {ECO:0000313|Ensembl:ENSP00000372349};+++[C3UJR9_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat Y-linked isoform 3 {ECO:0000313|EMBL:ACP43292.1}; Flags: Fragment;+++[E1NZ79_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 11 {ECO:0000313|EMBL:AAU87837.1};+++[E1NZ81_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 26 {ECO:0000313|EMBL:AAU93524.1};+++[E1NZ82_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 158 {ECO:0000313|EMBL:ABV49429.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 159 {ECO:0000313|EMBL:ABV49424.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 160 {ECO:0000313|EMBL:ABV49445.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 216 {ECO:0000313|EMBL:ABV49420.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 220 {ECO:0000313|EMBL:ABV82657.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 228 {ECO:0000313|EMBL:AAX07232.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 229 {ECO:0000313|EMBL:ABV49439.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 256 {ECO:0000313|EMBL:AAX07231.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 281 {ECO:0000313|EMBL:ABS19020.1}; SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 87 {ECO:0000313|EMBL:ABV82632.1};+++[E1NZ84_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 136 {ECO:0000313|EMBL:AAX07233.1};+++[E1NZ85_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 77 {ECO:0000313|EMBL:AAX07234.1};+++[E1NZ86_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 238 {ECO:0000313|EMBL:AAX07235.1};+++[E1NZ87_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 132 {ECO:0000313|EMBL:AAX07236.1};+++[E1NZ88_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 5 {ECO:0000313|EMBL:AAX07237.1};+++[E1NZ89_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 121 {ECO:0000313|EMBL:AAX07238.1};+++[E1NZ90_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 89 {ECO:0000313|EMBL:AAX07239.1};+++[E1NZ91_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 90 {ECO:0000313|EMBL:AAY16579.1};+++[E1NZ92_HUMAN|Unreviewed]SubName: Full=Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 75 {ECO:0000313|EMBL:AAY16580.1};+++[E1NZ93_HUMAN|Unrev"}}]
[7423,"'VEGFB'",2635,2855,2745,"05200///Pathways in cancer+++04151///PI3K-Akt signaling pathway+++04010///MAPK signaling pathway+++04926///Relaxin signaling pathway+++04015///Rap1 signaling pathway+++04510///Focal adhesion+++04014///Ras signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications",{"$nulls":3},"GO:0005576///extracellular region+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0031093///platelet alpha granule lumen","GO:0008201///heparin binding+++GO:0046982///protein heterodimerization activity+++GO:0042056///chemoattractant activity+++GO:0042803///protein homodimerization activity+++GO:0043185///vascular endothelial growth factor receptor 3 binding+++GO:0043183///vascular endothelial growth factor receptor 1 binding+++GO:0008083///growth factor activity+++GO:0043184///vascular endothelial growth factor receptor 2 binding+++GO:0005515///protein binding","GO:0001934///positive regulation of protein phosphorylation+++GO:0002576///platelet degranulation+++GO:0043117///positive regulation of vascular permeability+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0060976///coronary vasculature development+++GO:0043066///negative regulation of apoptotic process+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0045766///positive regulation of angiogenesis+++GO:0001525///angiogenesis+++GO:0051781///positive regulation of cell division+++GO:0001666///response to hypoxia+++GO:0060048///cardiac muscle contraction+++GO:0010469///regulation of signaling receptor activity+++GO:0006493///protein O-linked glycosylation+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0007507///heart development+++GO:0042493///response to drug+++GO:0002040///sprouting angiogenesis+++GO:0010629///negative regulation of gene expression+++GO:0050930///induction of positive chemotaxis+++GO:0050918///positive chemotaxis+++GO:0051897///positive regulation of protein kinase B signaling+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:0001938///positive regulation of endothelial cell proliferation+++GO:0035470///positive regulation of vascular wound healing+++GO:0070374///positive regulation of ERK1 and ERK2 cascade","IPR000072///PDGF/VEGF domain+++IPR029034///Cystine-knot cytokine+++IPR023581///Platelet-derived growth factor, conserved site+++IPR036841///Vascular endothelial growth factor, heparin-binding domain superfamily","[VEGFB_HUMAN|Reviewed]RecName: Full=Vascular endothelial growth factor B; Short=VEGF-B; AltName: Full=VEGF-related factor; Short=VRF; Flags: Precursor;+++[H0YGB6_HUMAN|Unreviewed]SubName: Full=Vascular endothelial growth factor B {ECO:0000313|Ensembl:ENSP00000442526}; Flags: Fragment;+++[Q7LAP4_HUMAN|Unreviewed]SubName: Full=Vascular endothelial growth factor B {ECO:0000313|EMBL:ABY87555.1}; SubName: Full=Vascular endothelial growth factor B isoform VEGF-B186 {ECO:0000313|EMBL:AAL79001.1};+++[Q8TEV2_HUMAN|Unreviewed]SubName: Full=Vascular endothelial growth factor B isoform VEGF-B167 {ECO:0000313|EMBL:AAL79000.1};+++[Q9UMT6_HUMAN|Unreviewed]SubName: Full=VEGF related factor {ECO:0000313|EMBL:AAA91464.1}; Flags: Fragment;"]
[7424,"'VEGFC'",170,188,179,"04510///Focal adhesion+++04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04010///MAPK signaling pathway+++05200///Pathways in cancer+++04926///Relaxin signaling pathway+++04014///Ras signaling pathway",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0031093///platelet alpha granule lumen+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0043185///vascular endothelial growth factor receptor 3 binding+++GO:0008083///growth factor activity+++GO:0042056///chemoattractant activity","GO:0001938///positive regulation of endothelial cell proliferation+++GO:0002576///platelet degranulation+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0001934///positive regulation of protein phosphorylation+++GO:0050714///positive regulation of protein secretion+++GO:0002040///sprouting angiogenesis+++GO:0007165///signal transduction+++GO:0030154///cell differentiation+++GO:0050930///induction of positive chemotaxis+++GO:0009887///animal organ morphogenesis+++GO:0042493///response to drug+++GO:1901492///positive regulation of lymphangiogenesis+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0001666///response to hypoxia+++GO:0060754///positive regulation of mast cell chemotaxis+++GO:0045776///negative regulation of blood pressure+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0007275///multicellular organism development+++GO:0010469///regulation of signaling receptor activity+++GO:0016331///morphogenesis of embryonic epithelium+++GO:0001525///angiogenesis+++GO:0045766///positive regulation of angiogenesis+++GO:0050918///positive chemotaxis+++GO:0051781///positive regulation of cell division+++GO:0038084///vascular endothelial growth factor signaling pathway+++GO:0008284///positive regulation of cell proliferation+++GO:0043536///positive regulation of blood vessel endothelial cell migration+++GO:0006929///substrate-dependent cell migration+++GO:0002052///positive regulation of neuroblast proliferation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0030947///regulation of vascular endothelial growth factor receptor signaling pathway","IPR029034///Cystine-knot cytokine+++IPR000072///PDGF/VEGF domain+++IPR023581///Platelet-derived growth factor, conserved site+++IPR004153///CXCXC repeat","[VEGFC_HUMAN|Reviewed]RecName: Full=Vascular endothelial growth factor C; Short=VEGF-C; AltName: Full=Flt4 ligand; Short=Flt4-L; AltName: Full=Vascular endothelial growth factor-related protein; Short=VRP; Flags: Precursor;+++[Q6FH59_HUMAN|Unreviewed]SubName: Full=VEGFC protein {ECO:0000313|EMBL:CAG46695.1};"]
[7448,"'VTN'",12,13,12.5,"04510///Focal adhesion+++05165///Human papillomavirus infection+++04512///ECM-receptor interaction+++04151///PI3K-Akt signaling pathway+++04610///Complement and coagulation cascades+++05205///Proteoglycans in cancer",{"$nulls":3},"GO:0048237///rough endoplasmic reticulum lumen+++GO:0071062///alphav-beta3 integrin-vitronectin complex+++GO:0005796///Golgi lumen+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm+++GO:0062023///collagen-containing extracellular matrix+++GO:0005604///basement membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0043231///intracellular membrane-bounded organelle+++GO:0072562///blood microparticle+++GO:0070062///extracellular exosome+++GO:0031012///extracellular matrix","GO:0050840///extracellular matrix binding+++GO:0042802///identical protein binding+++GO:0005518///collagen binding+++GO:0005201///extracellular matrix structural constituent+++GO:0005515///protein binding+++GO:0005044///scavenger receptor activity+++GO:0008201///heparin binding+++GO:0030247///polysaccharide binding+++GO:0005178///integrin binding","GO:0061302///smooth muscle cell-matrix adhesion+++GO:0051258///protein polymerization+++GO:0008283///cell proliferation+++GO:0097421///liver regeneration+++GO:0030449///regulation of complement activation+++GO:0006955///immune response+++GO:0007160///cell-matrix adhesion+++GO:0016477///cell migration+++GO:0006898///receptor-mediated endocytosis+++GO:0010951///negative regulation of endopeptidase activity+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0048260///positive regulation of receptor-mediated endocytosis+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0033627///cell adhesion mediated by integrin+++GO:0090303///positive regulation of wound healing+++GO:0030198///extracellular matrix organization+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:0007155///cell adhesion+++GO:0030949///positive regulation of vascular endothelial growth factor receptor signaling pathway+++GO:0030195///negative regulation of blood coagulation+++GO:0048709///oligodendrocyte differentiation+++GO:0035987///endodermal cell differentiation+++GO:0032092///positive regulation of protein binding","IPR036024///Somatomedin B-like domain superfamily+++IPR000585///Hemopexin-like domain+++IPR020436///Somatomedin B, chordata+++IPR001212///Somatomedin B domain+++IPR018487///Hemopexin-like repeats+++IPR018486///Hemopexin, conserved site+++IPR036375///Hemopexin-like domain superfamily","[VTNC_HUMAN|Reviewed]RecName: Full=Vitronectin; Short=VN; AltName: Full=S-protein; AltName: Full=Serum-spreading factor; AltName: Full=V75; Contains: RecName: Full=Vitronectin V65 subunit; Contains: RecName: Full=Vitronectin V10 subunit; Contains: RecName: Full=Somatomedin-B; Flags: Precursor;+++[D9ZGG2_HUMAN|Unreviewed]SubName: Full=Vitronectin {ECO:0000313|EMBL:ADL14521.1};+++[F5GX75_HUMAN|Unreviewed]SubName: Full=Vitronectin {ECO:0000313|Ensembl:ENSP00000440439}; Flags: Fragment;"]
[747,"'DAGLA'",232,251,241.5,"04745///Phototransduction - fly+++04925///Aldosterone synthesis and secretion+++04723///Retrograde endocannabinoid signaling",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0043196///varicosity+++GO:0099055///integral component of postsynaptic membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0045211///postsynaptic membrane","GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0047372///acylglycerol lipase activity","GO:0007216///G protein-coupled glutamate receptor signaling pathway+++GO:0019369///arachidonic acid metabolic process+++GO:0098921///retrograde trans-synaptic signaling by endocannabinoid+++GO:0046340///diacylglycerol catabolic process+++GO:0042136///neurotransmitter biosynthetic process+++GO:0071926///endocannabinoid signaling pathway+++GO:0006629///lipid metabolic process+++GO:0007405///neuroblast proliferation+++GO:0022008///neurogenesis+++GO:0016042///lipid catabolic process","IPR002921///Fungal lipase-like domain+++IPR029058///Alpha/Beta hydrolase fold","[DGLA_HUMAN|Reviewed]RecName: Full=Sn1-specific diacylglycerol lipase alpha; Short=DGL-alpha; EC=3.1.1.-; AltName: Full=Neural stem cell-derived dendrite regulator;+++[A0A024R517_HUMAN|Unreviewed]SubName: Full=Chromosome 11 open reading frame 11, isoform CRA_b {ECO:0000313|EMBL:EAW73961.1};+++[F5GY58_HUMAN|Unreviewed]SubName: Full=Sn1-specific diacylglycerol lipase alpha {ECO:0000313|Ensembl:ENSP00000440264};"]
[7507,"'XPA'",85,83,84,"03420///Nucleotide excision repair+++01524///Platinum drug resistance","H00403///Disorders of nucleotide excision repair+++H01428///Xeroderma pigmentosum (XP)",null,null,"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005662///DNA replication factor A complex+++GO:0000110///nucleotide-excision repair factor 1 complex+++GO:0045171///intercellular bridge","GO:0003684///damaged DNA binding+++GO:0019904///protein domain specific binding+++GO:0042803///protein homodimerization activity+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:1901255///nucleotide-excision repair involved in interstrand cross-link repair+++GO:0008630///intrinsic apoptotic signaling pathway in response to DNA damage+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0009411///response to UV+++GO:0006281///DNA repair+++GO:0009636///response to toxic substance+++GO:0010996///response to auditory stimulus+++GO:0034504///protein localization to nucleus+++GO:0006289///nucleotide-excision repair+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0006979///response to oxidative stress+++GO:0006284///base-excision repair+++GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0006974///cellular response to DNA damage stimulus+++GO:0070914///UV-damage excision repair+++GO:0035264///multicellular organism growth+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0010506///regulation of autophagy+++GO:0070911///global genome nucleotide-excision repair+++GO:0009650///UV protection","IPR000465///XPA+++IPR022656///XPA, C-terminal+++IPR022658///XPA, conserved site+++IPR022652///Zinc finger, XPA-type, conserved site+++IPR037129///XPA domain superfamily+++IPR009061///Putative DNA-binding domain superfamily","[XPA_HUMAN|Reviewed]RecName: Full=DNA repair protein complementing XP-A cells; AltName: Full=Xeroderma pigmentosum group A-complementing protein;+++[F2Z2T2_HUMAN|Unreviewed]SubName: Full=DNA repair protein-complementing XP-A cells {ECO:0000313|Ensembl:ENSP00000433006};+++[W0FSR8_HUMAN|Unreviewed]SubName: Full=Mutant xeroderma pigmentosum complementation group A {ECO:0000313|EMBL:AHF45877.1}; Flags: Fragment;"]
[7531,"'YWHAE'",8444,6264,7354,"04011///MAPK signaling pathway - yeast+++04390///Hippo signaling pathway+++04110///Cell cycle+++04391///Hippo signaling pathway - fly+++04722///Neurotrophin signaling pathway+++05203///Viral carcinogenesis+++04114///Oocyte meiosis+++04151///PI3K-Akt signaling pathway+++05169///Epstein-Barr virus infection","H00268///Lissencephaly (LIS)",null,null,"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0090724///central region of growth cone+++GO:0030424///axon+++GO:0005871///kinesin complex+++GO:0042470///melanosome+++GO:0005925///focal adhesion+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding+++GO:0046982///protein heterodimerization activity+++GO:0005246///calcium channel regulator activity+++GO:0050815///phosphoserine residue binding+++GO:0015459///potassium channel regulator activity+++GO:0019904///protein domain specific binding+++GO:0042826///histone deacetylase binding+++GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0042802///identical protein binding+++GO:0051219///phosphoprotein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0003723///RNA binding+++GO:0044325///ion channel binding+++GO:0045296///cadherin binding+++GO:0019899///enzyme binding+++GO:0044877///protein-containing complex binding+++GO:0097110///scaffold protein binding+++GO:0023026///MHC class II protein complex binding","GO:0035556///intracellular signal transduction+++GO:0099072///regulation of postsynaptic membrane neurotransmitter receptor levels+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0035329///hippo signaling+++GO:1900034///regulation of cellular response to heat+++GO:0086013///membrane repolarization during cardiac muscle cell action potential+++GO:0051480///regulation of cytosolic calcium ion concentration+++GO:1902309///negative regulation of peptidyl-serine dephosphorylation+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0034504///protein localization to nucleus+++GO:1901016///regulation of potassium ion transmembrane transporter activity+++GO:0016032///viral process+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:1901020///negative regulation of calcium ion transmembrane transporter activity+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0086091///regulation of heart rate by cardiac conduction+++GO:0034605///cellular response to heat+++GO:0046827///positive regulation of protein export from nucleus+++GO:0003064///regulation of heart rate by hormone+++GO:1905913///negative regulation of calcium ion export across plasma membrane+++GO:0000165///MAPK cascade+++GO:0061024///membrane organization+++GO:0021762///substantia nigra development+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0060306///regulation of membrane repolarization","IPR023410///14-3-3 domain+++IPR023409///14-3-3 protein, conserved site+++IPR000308///14-3-3 protein+++IPR036815///14-3-3 domain superfamily","[1433E_HUMAN|Reviewed]RecName: Full=14-3-3 protein epsilon; Short=14-3-3E;+++[B4DJF2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51975, moderately similar to 14-3-3 protein epsilon (14-3-3E) {ECO:0000313|EMBL:BAG58814.1};+++[I3L0W5_HUMAN|Unreviewed]SubName: Full=14-3-3 protein epsilon {ECO:0000313|Ensembl:ENSP00000458386};+++[I3L3T1_HUMAN|Unreviewed]SubName: Full=14-3-3 protein epsilon {ECO:0000313|Ensembl:ENSP00000460712};+++[K7EIT4_HUMAN|Unreviewed]SubName: Full=14-3-3 protein epsilon {ECO:0000313|Ensembl:ENSP00000464883}; Flags: Fragment;+++[K7EM20_HUMAN|Unreviewed]SubName: Full=14-3-3 protein epsilon {ECO:0000313|Ensembl:ENSP00000466324}; Flags: Fragment;+++[V9HW98_HUMAN|Unreviewed]SubName: Full=Epididymis luminal protein 2 {ECO:0000313|EMBL:ACJ13635.1};"]
[7549,"'ZNF2'",128.58,111.12,119.85,null,"H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0008270///zinc ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily","[ZNF2_HUMAN|Reviewed]RecName: Full=Zinc finger protein 2; AltName: Full=Zinc finger protein 2.2; AltName: Full=Zinc finger protein 661;+++[A0A087WYR5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 2 {ECO:0000313|Ensembl:ENSP00000482030};+++[A0A087X063_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 2 {ECO:0000313|Ensembl:ENSP00000483131};+++[B0AZN8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 2, isoform CRA_a {ECO:0000313|EMBL:EAX10715.1}; SubName: Full=cDNA, FLJ79478, highly similar to Homo sapiens zinc finger protein 2 (ZNF2), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF98720.1};+++[B4DR15_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56231, highly similar to Homo sapiens zinc finger protein 2 (ZNF2), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG61127.1};+++[Q68CY6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 2 {ECO:0000313|Ensembl:ENSP00000477960};"]
[7569,"'ZNF182'",65,83,74,null,"H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily","[ZN182_HUMAN|Reviewed]RecName: Full=Zinc finger protein 182; AltName: Full=Zinc finger protein 21; AltName: Full=Zinc finger protein KOX14;"]
[7592,"'ZNF41'",152,177,164.5,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily","[ZNF41_HUMAN|Reviewed]RecName: Full=Zinc finger protein 41;+++[A0A024R1C4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 41, isoform CRA_d {ECO:0000313|EMBL:EAW59304.1};+++[B1AQ29_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 41 {ECO:0000313|Ensembl:ENSP00000390385}; Flags: Fragment;"]
[763,"'CA5A'",0,1,0.5,"00910///Nitrogen metabolism","H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)+++H01400///Secondary hyperammonemia+++H01302///Hyperchlorhidrosis isolated (HCHLH)",null,"R00132///carbonate hydro-lyase (carbon-dioxide-forming); carbonic   Carbonic acid <=> CO2 + H2O+++R10092///carbonate hydro-lyase (carbon-dioxide-forming)   HCO3- + H+ <=> CO2 + H2O","GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0004089///carbonate dehydratase activity+++GO:0008270///zinc ion binding+++GO:0016829///lyase activity+++GO:0046872///metal ion binding","GO:0015701///bicarbonate transport","IPR036398///Alpha carbonic anhydrase domain superfamily+++IPR001148///Alpha carbonic anhydrase domain+++IPR018338///Carbonic anhydrase, alpha-class, conserved site+++IPR023561///Carbonic anhydrase, alpha-class","[CAH5A_HUMAN|Reviewed]RecName: Full=Carbonic anhydrase 5A, mitochondrial; EC=4.2.1.1; AltName: Full=Carbonate dehydratase VA; AltName: Full=Carbonic anhydrase VA; Short=CA-VA; Flags: Precursor;"]
[768,"'CA9'",36,75,55.5,"00910///Nitrogen metabolism","H01302///Hyperchlorhidrosis isolated (HCHLH)+++H01204///Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)+++H01400///Secondary hyperammonemia",null,"R10092///carbonate hydro-lyase (carbon-dioxide-forming)   HCO3- + H+ <=> CO2 + H2O+++R00132///carbonate hydro-lyase (carbon-dioxide-forming); carbonic   Carbonic acid <=> CO2 + H2O","GO:0016021///integral component of membrane+++GO:0031528///microvillus membrane+++GO:0005886///plasma membrane+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005730///nucleolus+++GO:0016323///basolateral plasma membrane","GO:0004089///carbonate dehydratase activity+++GO:0005515///protein binding+++GO:0016829///lyase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding","GO:0046903///secretion+++GO:0042493///response to drug+++GO:0015701///bicarbonate transport+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0033574///response to testosterone+++GO:0001666///response to hypoxia+++GO:0002009///morphogenesis of an epithelium","IPR023561///Carbonic anhydrase, alpha-class+++IPR036398///Alpha carbonic anhydrase domain superfamily+++IPR001148///Alpha carbonic anhydrase domain+++IPR018338///Carbonic anhydrase, alpha-class, conserved site+++IPR018429///Carbonic anhydrase 9","[CAH9_HUMAN|Reviewed]RecName: Full=Carbonic anhydrase 9; EC=4.2.1.1; AltName: Full=Carbonate dehydratase IX; AltName: Full=Carbonic anhydrase IX; Short=CA-IX; Short=CAIX; AltName: Full=Membrane antigen MN; AltName: Full=P54/58N; AltName: Full=Renal cell carcinoma-associated antigen G250; Short=RCC-associated antigen G250; AltName: Full=pMW1; Flags: Precursor;+++[A0A087WYS4_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase 9 {ECO:0000313|Ensembl:ENSP00000482050};+++[A0A0S2Z341_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase IX isoform 2 {ECO:0000313|EMBL:ALQ33411.1};+++[A0A0S2Z3D0_HUMAN|Unreviewed]SubName: Full=Carbonic anhydrase IX isoform 1 {ECO:0000313|EMBL:ALQ33410.1}; Flags: Fragment;"]
[7702,"'ZNF143'",196,151,173.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding","GO:0006383///transcription by RNA polymerase III+++GO:0006359///regulation of transcription by RNA polymerase III+++GO:0042795///snRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZN143_HUMAN|Reviewed]RecName: Full=Zinc finger protein 143; AltName: Full=SPH-binding factor; AltName: Full=Selenocysteine tRNA gene transcription-activating factor; Short=hStaf;+++[C9J2G7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000392323}; Flags: Fragment;+++[C9JCG1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000395221}; Flags: Fragment;+++[C9JRS3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000388628}; Flags: Fragment;+++[C9JTC5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000409432}; Flags: Fragment;+++[E7EN86_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000299606};+++[E9PJF2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000433743}; Flags: Fragment;+++[E9PLN4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000433221}; Flags: Fragment;+++[E9PLS7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000431306};+++[E9PMY8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000434922}; Flags: Fragment;+++[E9PPB0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000434638}; Flags: Fragment;+++[E9PS81_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000435881}; Flags: Fragment;+++[H7C1P6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 143 {ECO:0000313|Ensembl:ENSP00000401493}; Flags: Fragment;+++[Q9H176_HUMAN|Unreviewed]SubName: Full=ZNF143 protein {ECO:0000313|EMBL:CAC17610.1}; Flags: Fragment;+++[Q9H4D4_HUMAN|Unreviewed]SubName: Full=ZNF143 protein {ECO:0000313|EMBL:CAC14172.1}; Flags: Fragment;"]
[7730,"'ZNF177'",4.46,13,8.73,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0072562///blood microparticle+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum","GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006506///GPI anchor biosynthetic process+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box","[ZN177_HUMAN|Reviewed]RecName: Full=Zinc finger protein 177;+++[A0A0A6YYI6_HUMAN|Unreviewed]SubName: Full=Protein ZNF559-ZNF177 {ECO:0000313|Ensembl:ENSP00000415070};+++[K7EK36_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 177 {ECO:0000313|Ensembl:ENSP00000465438};+++[K7EQU1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 177 {ECO:0000313|Ensembl:ENSP00000467978}; Flags: Fragment;+++[V9H066_HUMAN|Unreviewed]SubName: Full=KRAB zinc finger protein {ECO:0000313|EMBL:AAB09748.1};"]
[7753,"'ZNF202'",84,88,86,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006629///lipid metabolic process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II","IPR013087///Zinc finger C2H2-type+++IPR003309///SCAN domain+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR038269///SCAN domain superfamily+++IPR036236///Zinc finger C2H2 superfamily","[ZN202_HUMAN|Reviewed]RecName: Full=Zinc finger protein 202; AltName: Full=Zinc finger protein with KRAB and SCAN domains 10;+++[A0A024R3M3_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 202, isoform CRA_a {ECO:0000313|EMBL:EAW67554.1};+++[A0A1D5RMT9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 202 {ECO:0000313|Ensembl:ENSP00000434338}; Flags: Fragment;+++[B3KN61_HUMAN|Unreviewed]SubName: Full=cDNA FLJ13689 fis, clone PLACE2000072, highly similar to Zinc finger protein 202 {ECO:0000313|EMBL:BAG51223.1};+++[E9PJL4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 202 {ECO:0000313|Ensembl:ENSP00000431761}; Flags: Fragment;+++[E9PM99_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 202 {ECO:0000313|Ensembl:ENSP00000431223}; Flags: Fragment;"]
[7771,"'ZNF112'",55,42,48.5,null,"H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding","GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily","[ZN112_HUMAN|Reviewed]RecName: Full=Zinc finger protein 112; Short=Zfp-112; AltName: Full=Zinc finger protein 228;+++[K7EIR6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000464862};+++[K7EN57_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000466797}; Flags: Fragment;+++[K7ENS0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000467064}; Flags: Fragment;+++[K7EQV5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 {ECO:0000313|Ensembl:ENSP00000467994}; Flags: Fragment;+++[Q0VG01_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 112 homolog (Mouse) {ECO:0000313|EMBL:AAI17224.1};"]
[780,"'DDR1'",6723,7936,7329.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0043235///receptor complex+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005518///collagen binding+++GO:0038062///protein tyrosine kinase collagen receptor activity+++GO:0004714///transmembrane receptor protein tyrosine kinase activity+++GO:0004713///protein tyrosine kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0016740///transferase activity+++GO:0046872///metal ion binding+++GO:0016301///kinase activity+++GO:0004672///protein kinase activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding","GO:0070374///positive regulation of ERK1 and ERK2 cascade+++GO:0006468///protein phosphorylation+++GO:0043583///ear development+++GO:0030154///cell differentiation+++GO:0007155///cell adhesion+++GO:0044319///wound healing, spreading of cells+++GO:0043066///negative regulation of apoptotic process+++GO:0001558///regulation of cell growth+++GO:0007595///lactation+++GO:0038083///peptidyl-tyrosine autophosphorylation+++GO:0010715///regulation of extracellular matrix disassembly+++GO:0009968///negative regulation of signal transduction+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0007565///female pregnancy+++GO:1990138///neuron projection extension+++GO:0001952///regulation of cell-matrix adhesion+++GO:0008285///negative regulation of cell proliferation+++GO:0016310///phosphorylation+++GO:0061564///axon development+++GO:0046777///protein autophosphorylation+++GO:0060444///branching involved in mammary gland duct morphogenesis+++GO:0060749///mammary gland alveolus development+++GO:0030198///extracellular matrix organization+++GO:0014909///smooth muscle cell migration+++GO:0007566///embryo implantation+++GO:0038063///collagen-activated tyrosine kinase receptor signaling pathway+++GO:0061302///smooth muscle cell-matrix adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway","IPR000719///Protein kinase domain+++IPR008979///Galactose-binding-like domain superfamily+++IPR020635///Tyrosine-protein kinase, catalytic domain+++IPR008266///Tyrosine-protein kinase, active site+++IPR011009///Protein kinase-like domain superfamily+++IPR029553///Epithelial discoidin domain-containing receptor 1+++IPR000421///Coagulation factor 5/8 C-terminal domain+++IPR001245///Serine-threonine/tyrosine-protein kinase, catalytic domain+++IPR002011///Tyrosine-protein kinase, receptor class II, conserved site","[DDR1_HUMAN|Reviewed]RecName: Full=Epithelial discoidin domain-containing receptor 1; Short=Epithelial discoidin domain receptor 1; EC=2.7.10.1; AltName: Full=CD167 antigen-like family member A; AltName: Full=Cell adhesion kinase; AltName: Full=Discoidin receptor tyrosine kinase; AltName: Full=HGK2; AltName: Full=Mammary carcinoma kinase 10; Short=MCK-10; AltName: Full=Protein-tyrosine kinase 3A; AltName: Full=Protein-tyrosine kinase RTK-6; AltName: Full=TRK E; AltName: Full=Tyrosine kinase DDR; AltName: Full=Tyrosine-protein kinase CAK; AltName: CD_antigen=CD167a; Flags: Precursor;+++[A0A024RCJ0_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor family, member 1, isoform CRA_b {ECO:0000313|EMBL:EAX03343.1};+++[A0A024RCL1_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor family, member 1, isoform CRA_a {ECO:0000313|EMBL:EAX03342.1};+++[A0A024RCQ1_HUMAN|Unreviewed]SubName: Full=DDR1 {ECO:0000313|EMBL:AQY76774.1}; SubName: Full=Discoidin domain receptor family, member 1, isoform CRA_d {ECO:0000313|EMBL:EAX03341.1};+++[A0A0A0MSX3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000405998};+++[A0A0G2JHK4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000390043}; Flags: Fragment;+++[A0A0G2JI85_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000396139}; Flags: Fragment;+++[A0A0G2JIA2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000396609}; Flags: Fragment;+++[A0A0G2JIZ7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000403454}; Flags: Fragment;+++[A0A0G2JJA0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000406200}; Flags: Fragment;+++[A0A0G2JNZ7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000482421};+++[A0A140T972_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000394161}; Flags: Fragment;+++[A0A140T9T5_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000412396}; Flags: Fragment;+++[A2ABL0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000379631}; Flags: Fragment;+++[A2ABL2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000409682}; Flags: Fragment;+++[A2ABM8_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000398682}; Flags: Fragment;+++[D6R9C4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000422974}; Flags: Fragment;+++[D6RAJ3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421753};+++[D6RB35_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424468}; Flags: Fragment;+++[D6RB82_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424346}; Flags: Fragment;+++[D6RBU7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000392413}; Flags: Fragment;+++[D6RGW5_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421152}; Flags: Fragment;+++[E7EN94_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000420833}; Flags: Fragment;+++[E7ENJ2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000423492}; Flags: Fragment;+++[E7EPH4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000426420}; Flags: Fragment;+++[E7EPN2_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000426229}; Flags: Fragment;+++[E7EQ23_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000425713}; Flags: Fragment;+++[E7EQ30_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000390593}; Flags: Fragment;+++[E7ERI6_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000394273}; Flags: Fragment;+++[E7ERN0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000422467}; Flags: Fragment;+++[E7ES06_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000422331}; Flags: Fragment;+++[E7ESR9_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000425113}; Flags: Fragment;+++[E7ETI3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000427597}; Flags: Fragment;+++[E7ETX3_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000423906}; Flags: Fragment;+++[E7EUD5_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000427369}; Flags: Fragment;+++[E7EUP7_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000423749}; Flags: Fragment;+++[E7EVT1_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421719}; Flags: Fragment;+++[E7EVW6_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000421189}; Flags: Fragment;+++[E7EX99_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424758}; Flags: Fragment;+++[E7EXB0_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424703}; Flags: Fragment;+++[H0Y717_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000409400}; Flags: Fragment;+++[H0Y9F4_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000424003}; Flags: Fragment;+++[H0YAH6_HUMAN|Unreviewed]SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000427124}; Flags: Fragment;+++[Q96T61_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor DDR1e {ECO:0000313|EMBL:AAK48843.1}; Flags: Fragment;+++[Q96T62_HUMAN|Unreviewed]SubName: Full=Discoidin domain receptor DDR1d {ECO:0000313|EMBL:AAK48842.1}; Flags: Fragment;"]
[7840,"'ALMS1'",101,148,124.5,null,"H00417///Alstrom syndrome (AS)",null,null,"GO:0005623///cell+++GO:0000922///spindle pole+++GO:0005815///microtubule organizing center+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005929///cilium+++GO:0005814///centriole","GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0051393///alpha-actinin binding","GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0051492///regulation of stress fiber assembly+++GO:0016197///endosomal transport","IPR029299///ALMS motif+++IPR028781///Alstrom syndrome protein 1","[ALMS1_HUMAN|Reviewed]RecName: Full=Alstrom syndrome protein 1;+++[A0A087WTU9_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome protein 1 {ECO:0000313|Ensembl:ENSP00000478155};+++[A0A087WV20_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome protein 1 {ECO:0000313|Ensembl:ENSP00000479094};+++[A0A1P8DS31_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome 1 splice variant {ECO:0000313|EMBL:APU92089.1}; Flags: Fragment;+++[A0A1P8DS37_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome 1 splice variant {ECO:0000313|EMBL:APU92090.1}; Flags: Fragment;+++[A0A2R8Y7Z9_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome protein 1 {ECO:0000313|Ensembl:ENSP00000496540}; Flags: Fragment;+++[A1YZ18_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome 1 splice variant {ECO:0000313|EMBL:ABL96615.1}; Flags: Fragment;+++[D6W5H5_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome 1, isoform CRA_c {ECO:0000313|EMBL:EAW99731.1};+++[H7C1D9_HUMAN|Unreviewed]SubName: Full=Alstrom syndrome protein 1 {ECO:0000313|Ensembl:ENSP00000399833}; Flags: Fragment;"]
[7873,"'MANF'",1096,913,1004.5,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0033018///sarcoplasmic reticulum lumen+++GO:0005576///extracellular region+++GO:0016529///sarcoplasmic reticulum+++GO:0048471///perinuclear region of cytoplasm+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005788///endoplasmic reticulum lumen","GO:0003723///RNA binding+++GO:0008083///growth factor activity+++GO:0008289///lipid binding","GO:0010469///regulation of signaling receptor activity+++GO:0002576///platelet degranulation+++GO:1905897///regulation of response to endoplasmic reticulum stress+++GO:0031175///neuron projection development+++GO:0006986///response to unfolded protein","IPR019345///Armet protein+++IPR036361///SAP domain superfamily","[MANF_HUMAN|Reviewed]RecName: Full=Mesencephalic astrocyte-derived neurotrophic factor; AltName: Full=Arginine-rich protein; AltName: Full=Protein ARMET; Flags: Precursor;+++[A8K878_HUMAN|Unreviewed]SubName: Full=Mesencephalic astrocyte-derived neurotrophic factor {ECO:0000313|Ensembl:ENSP00000432799}; SubName: Full=cDNA FLJ77177, highly similar to Homo sapiens arginine-rich, mutated in early stage tumors (ARMET), mRNA {ECO:0000313|EMBL:BAF84932.1};+++[H7C2D6_HUMAN|Unreviewed]SubName: Full=Mesencephalic astrocyte-derived neurotrophic factor {ECO:0000313|Ensembl:ENSP00000405280}; Flags: Fragment;"]
[78996,"'CYREN'",365,306,335.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006281///DNA repair+++GO:2001033///negative regulation of double-strand break repair via nonhomologous end joining","IPR028278///Modulator of retrovirus infection","[CYREN_HUMAN|Reviewed]RecName: Full=Cell cycle regulator of non-homologous end joining {ECO:0000303|PubMed:28959974}; Short=Cell cycle regulator of NHEJ {ECO:0000303|PubMed:28959974}; AltName: Full=Modulator of retrovirus infection homolog {ECO:0000250|UniProtKB:Q09HN1};+++[C9JKC7_HUMAN|Unreviewed]SubName: Full=Cell cycle regulator of non-homologous end joining {ECO:0000313|Ensembl:ENSP00000389941};"]
[79016,"'DDA1'",4244,3166,3705,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex","GO:0005515///protein binding","GO:0043687///post-translational protein modification+++GO:0032434///regulation of proteasomal ubiquitin-dependent protein catabolic process","IPR018276///DET1- and DDB1-associated protein 1, N-terminal+++IPR033575///DET1- and DDB1-associated protein 1","[DDA1_HUMAN|Reviewed]RecName: Full=DET1- and DDB1-associated protein 1; AltName: Full=Placenta cross-immune reaction antigen 1; Short=PCIA-1;+++[A0A024R7J7_HUMAN|Unreviewed]SubName: Full=DDA1, isoform CRA_a {ECO:0000313|EMBL:EAW84594.1};"]
[79036,"'KXD1'",2666,1843.93,2254.965,{"$nulls":4},"GO:0016020///membrane+++GO:0099078///BORC complex+++GO:0005765///lysosomal membrane+++GO:0005764///lysosome+++GO:0031083///BLOC-1 complex","GO:0005515///protein binding","GO:0032418///lysosome localization+++GO:0016192///vesicle-mediated transport","IPR019371///Uncharacterised domain KxDL+++IPR039843///KxDL motif-containing protein 1-like","[KXDL1_HUMAN|Reviewed]RecName: Full=KxDL motif-containing protein 1;+++[A0A024R7M2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW84714.1};+++[M0QX74_HUMAN|Unreviewed]SubName: Full=KxDL motif-containing protein 1 {ECO:0000313|Ensembl:ENSP00000468949}; Flags: Fragment;+++[M0QXN9_HUMAN|Unreviewed]SubName: Full=KxDL motif-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469288}; Flags: Fragment;+++[M0QXP3_HUMAN|Unreviewed]SubName: Full=KxDL motif-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469294}; Flags: Fragment;+++[M0QY77_HUMAN|Unreviewed]SubName: Full=KxDL motif-containing protein 1 {ECO:0000313|Ensembl:ENSP00000469648};+++[M0R0B4_HUMAN|Unreviewed]SubName: Full=KxDL motif-containing protein 1 {ECO:0000313|Ensembl:ENSP00000471127}; Flags: Fragment;+++[M0R228_HUMAN|Unreviewed]SubName: Full=KxDL motif-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472268}; Flags: Fragment;+++[M0R2G3_HUMAN|Unreviewed]SubName: Full=KxDL motif-containing protein 1 {ECO:0000313|Ensembl:ENSP00000472535};+++[Q7Z4E2_HUMAN|Unreviewed]SubName: Full=MSTP096 {ECO:0000313|EMBL:AAQ13622.1};"]
[79065,"'ATG9A'",1819,2132,1975.5,"04136///Autophagy - other+++04137///Mitophagy - animal+++04138///Autophagy - yeast+++04140///Autophagy - animal",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000421///autophagosome membrane+++GO:0005783///endoplasmic reticulum+++GO:0031902///late endosome membrane+++GO:0005776///autophagosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005770///late endosome+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0005789///endoplasmic reticulum membrane+++GO:0055037///recycling endosome+++GO:0000407///phagophore assembly site+++GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005768///endosome","GO:0005515///protein binding","GO:0015031///protein transport+++GO:0044805///late nucleophagy+++GO:0034497///protein localization to phagophore assembly site+++GO:0000045///autophagosome assembly+++GO:0000422///autophagy of mitochondrion+++GO:0006914///autophagy","IPR007241///Autophagy-related protein 9","[ATG9A_HUMAN|Reviewed]RecName: Full=Autophagy-related protein 9A; AltName: Full=APG9-like 1; AltName: Full=mATG9;+++[A0A024R438_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 9 {ECO:0000256|RuleBase:RU364027};+++[C9IYZ9_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000406785}; Flags: Fragment;+++[C9JD65_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 9 {ECO:0000256|RuleBase:RU364027}; Flags: Fragment;+++[C9JDK4_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000404750}; Flags: Fragment;+++[C9JFV2_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000416435}; Flags: Fragment;+++[C9JKV7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000409164}; Flags: Fragment;+++[C9JS65_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000394345}; Flags: Fragment;+++[C9JX27_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000413569}; Flags: Fragment;+++[C9JXG2_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000401530}; Flags: Fragment;+++[F2Z3I6_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 9A {ECO:0000313|Ensembl:ENSP00000390704};+++[H7C1G6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 9 {ECO:0000256|RuleBase:RU364027}; Flags: Fragment;"]
[79086,"'SMIM7'",346,275,310.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IPR037659///Small integral membrane protein 7","[SMIM7_HUMAN|Reviewed]RecName: Full=Small integral membrane protein 7; Flags: Precursor;+++[B7WNH4_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 7 {ECO:0000313|Ensembl:ENSP00000351569};+++[E9PLH2_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 7 {ECO:0000313|Ensembl:ENSP00000435127};+++[E9PNA8_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 7 {ECO:0000313|Ensembl:ENSP00000432842};+++[E9PP42_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 7 {ECO:0000313|Ensembl:ENSP00000436448};+++[M0R0R3_HUMAN|Unreviewed]SubName: Full=Small integral membrane protein 7 {ECO:0000313|Ensembl:ENSP00000471391};"]
[79132,"'DHX58'",467,470,468.5,"04622///RIG-I-like receptor signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm","GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0003727///single-stranded RNA binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0003725///double-stranded RNA binding+++GO:0046872///metal ion binding+++GO:0005524///ATP binding","GO:0032480///negative regulation of type I interferon production+++GO:0002376///immune system process+++GO:0045824///negative regulation of innate immune response+++GO:0045087///innate immune response+++GO:0032481///positive regulation of type I interferon production+++GO:0009615///response to virus+++GO:0039534///negative regulation of MDA-5 signaling pathway+++GO:0016032///viral process+++GO:0051607///defense response to virus+++GO:1900245///positive regulation of MDA-5 signaling pathway+++GO:0009617///response to bacterium+++GO:1900246///positive regulation of RIG-I signaling pathway+++GO:0039536///negative regulation of RIG-I signaling pathway+++GO:0045088///regulation of innate immune response","IPR001650///Helicase, C-terminal+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR021673///RIG-I-like receptor, C-terminal regulatory domain+++IPR038557///RIG-I-like receptor, C-terminal domain superfamily+++IPR006935///Helicase/UvrB, N-terminal+++IPR014001///Helicase superfamily 1/2, ATP-binding domain","[DHX58_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DHX58; EC=3.6.4.13; AltName: Full=Probable ATP-dependent helicase LGP2; AltName: Full=Protein D11Lgp2 homolog; AltName: Full=RIG-I-like receptor 3; Short=RLR-3; AltName: Full=RIG-I-like receptor LGP2; Short=RLR;+++[A0A024R1Y5_HUMAN|Unreviewed]SubName: Full=Likely ortholog of mouse D11lgp2, isoform CRA_b {ECO:0000313|EMBL:EAW60798.1};+++[C9JE76_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DHX58 {ECO:0000313|Ensembl:ENSP00000404639}; Flags: Fragment;+++[C9JG98_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DHX58 {ECO:0000313|Ensembl:ENSP00000416389}; Flags: Fragment;+++[K7EMZ5_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DHX58 {ECO:0000313|Ensembl:ENSP00000466721}; Flags: Fragment;+++[K7EPP0_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DHX58 {ECO:0000313|Ensembl:ENSP00000467470}; Flags: Fragment;"]
[79153,"'GDPD3'",3,6,4.5,"00565///Ether lipid metabolism",null,null,"R07388///1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine ethanolaminehydrolase   1-(1-Alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-(1-Alkenyl)-sn-glycero-3-phosphate + Ethanolamine","GO:0048471///perinuclear region of cytoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0008081///phosphoric diester hydrolase activity+++GO:0016787///hydrolase activity","GO:0006644///phospholipid metabolic process+++GO:0006629///lipid metabolic process+++GO:0034638///phosphatidylcholine catabolic process","IPR017946///PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily+++IPR030395///Glycerophosphodiester phosphodiesterase domain","[GDPD3_HUMAN|Reviewed]RecName: Full=Lysophospholipase D GDPD3 {ECO:0000305}; EC=3.1.4.- {ECO:0000250|UniProtKB:Q99LY2}; AltName: Full=Glycerophosphodiester phosphodiesterase 7 {ECO:0000250|UniProtKB:Q99LY2}; AltName: Full=Glycerophosphodiester phosphodiesterase domain-containing protein 3;+++[H3BMN9_HUMAN|Unreviewed]SubName: Full=Lysophospholipase D GDPD3 {ECO:0000313|Ensembl:ENSP00000454472}; Flags: Fragment;+++[H3BPX3_HUMAN|Unreviewed]SubName: Full=Lysophospholipase D GDPD3 {ECO:0000313|Ensembl:ENSP00000455508}; Flags: Fragment;"]
[79175,"'ZNF343'",102,116,109,null,"H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN343_HUMAN|Reviewed]RecName: Full=Zinc finger protein 343;+++[A0A087WZQ2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 343 {ECO:0000313|Ensembl:ENSP00000482819};+++[A0A0A0MSR0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 343 {ECO:0000313|Ensembl:ENSP00000399682}; Flags: Fragment;+++[A0A0A0MT63_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 343 {ECO:0000313|Ensembl:ENSP00000416488}; Flags: Fragment;"]
[7922,"'SLC39A7'",2932,2971,2951.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005794///Golgi apparatus","GO:0005385///zinc ion transmembrane transporter activity+++GO:0005515///protein binding+++GO:0046873///metal ion transmembrane transporter activity","GO:0030001///metal ion transport+++GO:0055085///transmembrane transport+++GO:0071577///zinc ion transmembrane transport+++GO:0006829///zinc ion transport+++GO:0006811///ion transport+++GO:0006882///cellular zinc ion homeostasis","IPR003689///Zinc/iron permease","[S39A7_HUMAN|Reviewed]RecName: Full=Zinc transporter SLC39A7; AltName: Full=Histidine-rich membrane protein Ke4; AltName: Full=Really interesting new gene 5 protein; AltName: Full=Solute carrier family 39 member 7; AltName: Full=Zrt-, Irt-like protein 7; Short=ZIP7;+++[A0A024RCX7_HUMAN|Unreviewed]SubName: Full=SLC39A7 {ECO:0000313|EMBL:AQY77114.1}; SubName: Full=Solute carrier family 39 (Zinc transporter), member 7, isoform CRA_a {ECO:0000313|EMBL:EAX03681.1};+++[A2AAT0_HUMAN|Unreviewed]SubName: Full=Zinc transporter SLC39A7 {ECO:0000313|Ensembl:ENSP00000400978}; Flags: Fragment;+++[B4DZZ8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52943, highly similar to Zinc transporter SLC39A7 {ECO:0000313|EMBL:BAG64260.1};+++[Q29984_HUMAN|Unreviewed]SubName: Full=Non-class II protein {ECO:0000313|EMBL:AAA63219.1}; Flags: Fragment;"]
[79412,"'KREMEN2'",14,16,15,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0031901///early endosome membrane",null,"GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0060173///limb development+++GO:0016055///Wnt signaling pathway+++GO:0030279///negative regulation of ossification","IPR002889///Carbohydrate-binding WSC+++IPR000859///CUB domain+++IPR035914///Spermadhesin, CUB domain superfamily+++IPR017076///Kremen+++IPR038178///Kringle superfamily+++IPR013806///Kringle-like fold+++IPR018056///Kringle, conserved site+++IPR000001///Kringle","[KREM2_HUMAN|Reviewed]RecName: Full=Kremen protein 2; AltName: Full=Dickkopf receptor 2; AltName: Full=Kringle domain-containing transmembrane protein 2; AltName: Full=Kringle-containing protein marking the eye and the nose; Flags: Precursor;+++[Q53F67_HUMAN|Unreviewed]SubName: Full=Kringle-containing transmembrane protein 2 isoform b variant {ECO:0000313|EMBL:BAD97142.1}; Flags: Fragment;"]
[7957,"'EPM2A'",23,45,34,null,"H01892///Peripheral T cell lymphoma (PTCL)+++H01601///Anaplastic large-cell lymphoma+++H00810///Progressive myoclonic epilepsy (PME/ EPM)+++H01994///Lafora disease",null,null,"GO:0005634///nucleus+++GO:0098556///cytoplasmic side of rough endoplasmic reticulum membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0016791///phosphatase activity+++GO:0019203///carbohydrate phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0042803///protein homodimerization activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0046872///metal ion binding+++GO:2001069///glycogen binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:2001070///starch binding+++GO:0008138///protein tyrosine/serine/threonine phosphatase activity+++GO:0046983///protein dimerization activity+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0030246///carbohydrate binding","GO:0006470///protein dephosphorylation+++GO:0046959///habituation+++GO:0016239///positive regulation of macroautophagy+++GO:0032197///transposition, RNA-mediated+++GO:0016311///dephosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0010923///negative regulation of phosphatase activity+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006914///autophagy+++GO:0006310///DNA recombination+++GO:0005977///glycogen metabolic process+++GO:0046838///phosphorylated carbohydrate dephosphorylation+++GO:0007399///nervous system development+++GO:0005978///glycogen biosynthetic process+++GO:0035305///negative regulation of dephosphorylation","IPR000340///Dual specificity phosphatase, catalytic domain+++IPR013783///Immunoglobulin-like fold+++IPR013784///Carbohydrate-binding-like fold+++IPR024950///Dual specificity phosphatase+++IPR002044///Carbohydrate binding module family 20+++IPR020422///Dual specificity protein phosphatase domain+++IPR034831///Laforin, CBM20 domain+++IPR029021///Protein-tyrosine phosphatase-like+++IPR016130///Protein-tyrosine phosphatase, active site+++IPR000387///Tyrosine specific protein phosphatases domain","[EPM2A_HUMAN|Reviewed]RecName: Full=Laforin {ECO:0000303|PubMed:11001928}; EC=3.1.3.- {ECO:0000269|PubMed:16901901, ECO:0000269|PubMed:23922729, ECO:0000269|PubMed:25538239, ECO:0000269|PubMed:25544560, ECO:0000269|PubMed:26231210}; EC=3.1.3.16 {ECO:0000305|PubMed:11001928}; EC=3.1.3.48 {ECO:0000269|PubMed:11001928, ECO:0000269|PubMed:11220751}; AltName: Full=Glucan phosphatase {ECO:0000303|PubMed:16901901, ECO:0000303|PubMed:25538239}; AltName: Full=Glycogen phosphatase {ECO:0000303|PubMed:25538239, ECO:0000303|PubMed:25544560}; AltName: Full=Lafora PTPase; Short=LAFPTPase {ECO:0000303|PubMed:11175283};+++[H0UI04_HUMAN|Unreviewed]SubName: Full=Epilepsy, progressive myoclonus type 2A, Lafora disease (Laforin), isoform CRA_a {ECO:0000313|EMBL:EAW47843.1};+++[H0Y6I8_HUMAN|Unreviewed]SubName: Full=Laforin, isoform 9 {ECO:0000313|Ensembl:ENSP00000405913};"]
[79590,"'MRPL24'",613,467,540,"03010///Ribosome",null,"M00178///Ribosome, bacteria+++M00179///Ribosome, archaea",null,"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0005840///ribosome","GO:0003735///structural constituent of ribosome","GO:0070125///mitochondrial translational elongation+++GO:0006412///translation+++GO:0070126///mitochondrial translational termination","IPR014722///Ribosomal protein L2, domain 2+++IPR005824///KOW+++IPR003256///Ribosomal protein L24+++IPR005825///Ribosomal protein L24/L26, conserved site+++IPR008991///Translation protein SH3-like domain superfamily","[RM24_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L24, mitochondrial; Short=L24mt; Short=MRP-L24; AltName: Full=Mitochondrial large ribosomal subunit protein uL24m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[X6RHI2_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L24, mitochondrial {ECO:0000313|Ensembl:ENSP00000406681}; Flags: Fragment;+++[X6RIR5_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L24, mitochondrial {ECO:0000313|Ensembl:ENSP00000409803}; Flags: Fragment;+++[X6RJ73_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L24, mitochondrial {ECO:0000313|Ensembl:ENSP00000411369}; Flags: Fragment;"]
[79616,"'CCNJL'",259,311,285,"04140///Autophagy - animal+++03320///PPAR signaling pathway+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0000307///cyclin-dependent protein kinase holoenzyme complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0019901///protein kinase binding+++GO:0004672///protein kinase activity+++GO:0016538///cyclin-dependent protein serine/threonine kinase regulator activity","GO:0006468///protein phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0007088///regulation of mitotic nuclear division+++GO:0045787///positive regulation of cell cycle+++GO:0008284///positive regulation of cell proliferation","IPR004367///Cyclin, C-terminal domain+++IPR006671///Cyclin, N-terminal+++IPR036915///Cyclin-like superfamily+++IPR013763///Cyclin-like+++IPR039361///Cyclin","[CCNJL_HUMAN|Reviewed]RecName: Full=Cyclin-J-like protein;+++[A0A2R8Y754_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000496026};+++[A0A2R8Y7P8_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000496436};+++[A0A2R8YFU1_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000496735};+++[B4DZA8_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000257536}; SubName: Full=cDNA FLJ60987, weakly similar to Mus musculus cyclin J (Ccnj), mRNA {ECO:0000313|EMBL:BAG64020.1};+++[E5RFJ6_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000428836}; Flags: Fragment;+++[E7EN43_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000427960};+++[F6RF56_HUMAN|Unreviewed]SubName: Full=Cyclin-J-like protein {ECO:0000313|Ensembl:ENSP00000446367};"]
[79635,"'CCDC121'",18,11,14.5,{"$nulls":5},"GO:0005515///protein binding",null,"IPR032777///Domain of unknown function DUF4515","[CC121_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 121;+++[E5RHR4_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 121 {ECO:0000313|Ensembl:ENSP00000428530}; Flags: Fragment;"]
[79654,"'HECTD3'",1132,959,1045.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016874///ligase activity+++GO:0019905///syntaxin binding","GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process","IPR035983///HECT, E3 ligase catalytic domain+++IPR000569///HECT domain+++IPR008979///Galactose-binding-like domain superfamily+++IPR004939///APC10/DOC domain","[HECD3_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase HECTD3; EC=2.3.2.26; AltName: Full=HECT domain-containing protein 3; AltName: Full=HECT-type E3 ubiquitin transferase HECTD3;+++[A1A4G1_HUMAN|Unreviewed]SubName: Full=HECT domain containing 3 {ECO:0000313|EMBL:AAI26353.1}; SubName: Full=HECT domain containing 3, isoform CRA_a {ECO:0000313|EMBL:EAX07009.1}; SubName: Full=cDNA FLJ31983 fis, clone NT2RP7008557, highly similar to Probable E3 ubiquitin-protein ligase HECTD3 {ECO:0000313|EMBL:BAG51742.1};+++[B3KU34_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39143 fis, clone OCBBF1000054, highly similar to Probable E3 ubiquitin-protein ligase HECTD3 {ECO:0000313|EMBL:BAG53296.1};"]
[79673,"'ZNF329'",134.99,153.99,144.49,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN329_HUMAN|Reviewed]RecName: Full=Zinc finger protein 329;+++[A0A024R4Q4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 329, isoform CRA_a {ECO:0000313|EMBL:EAW72562.1};+++[M0R136_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 329 {ECO:0000313|Ensembl:ENSP00000471614}; Flags: Fragment;"]
[79693,"'YRDC'",171,121,146,{"$nulls":4},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion","GO:0003725///double-stranded RNA binding+++GO:0016779///nucleotidyltransferase activity+++GO:0000049///tRNA binding","GO:0006450///regulation of translational fidelity+++GO:0051051///negative regulation of transport","IPR006070///YrdC-like domain+++IPR017945///DHBP synthase RibB-like alpha/beta domain superfamily","[YRDC_HUMAN|Reviewed]RecName: Full=YrdC domain-containing protein, mitochondrial; AltName: Full=Dopamine receptor-interacting protein 3; AltName: Full=Ischemia/reperfusion-inducible protein homolog; Short=hIRIP; Flags: Precursor;"]
[79712,"'GTDC1'",160,180,170,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups",null,"IPR001296///Glycosyl transferase, family 1+++IPR022701///Glycosyltransferase family 1, N-terminal","[GTDC1_HUMAN|Reviewed]RecName: Full=Glycosyltransferase-like domain-containing protein 1; AltName: Full=Mannosyltransferase-like protein Xa {ECO:0000303|PubMed:21821951}; AltName: Full=Mat-Xa {ECO:0000303|PubMed:21821951};+++[B8ZZ45_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000386691};+++[C9J2C5_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000400661}; Flags: Fragment;+++[C9JIH3_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000403869}; Flags: Fragment;+++[F2Z2V8_HUMAN|Unreviewed]SubName: Full=Glycosyltransferase-like domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000395932};+++[L0R871_HUMAN|Unreviewed]SubName: Full=Alternative protein GTDC1 {ECO:0000313|EMBL:CCO13741.1};"]
[79730,"'NSUN7'",39,33,36,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0045202///synapse+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0030027///lamellipodium+++GO:0030426///growth cone","GO:0016740///transferase activity+++GO:0008168///methyltransferase activity+++GO:0003723///RNA binding","GO:0032259///methylation","IPR001678///SAM-dependent methyltransferase RsmB/NOP2-type+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase","[NSUN7_HUMAN|Reviewed]RecName: Full=Putative methyltransferase NSUN7; EC=2.1.1.-; AltName: Full=NOL1/NOP2/Sun domain family member 7;"]
[79750,"'ZNF385D'",73,97,85,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding","GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0072332///intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0032197///transposition, RNA-mediated","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR003604///Matrin/U1-C-like, C2H2-type zinc finger+++IPR022755///Zinc finger, double-stranded RNA binding","[Z385D_HUMAN|Reviewed]RecName: Full=Zinc finger protein 385D; AltName: Full=Zinc finger protein 659;+++[A0A2R8Y4E5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385D {ECO:0000313|Ensembl:ENSP00000493727};+++[A0A2R8YG37_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385D {ECO:0000313|Ensembl:ENSP00000495609}; Flags: Fragment;+++[F8WEJ0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 385D {ECO:0000313|Ensembl:ENSP00000388232};"]
[79774,"'GRTP1'",41.94,34.4,38.17,"04140///Autophagy - animal+++04145///Phagosome+++04142///Lysosome+++05152///Tuberculosis","H01781///Autophagic vacuolar myopathy+++H00150///Danon disease",null,null,"GO:0005623///cell","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport","IPR035969///Rab-GTPase-TBC domain superfamily+++IPR000195///Rab-GTPase-TBC domain","[GRTP1_HUMAN|Reviewed]RecName: Full=Growth hormone-regulated TBC protein 1; AltName: Full=TBC1 domain family member 6;+++[A0A087X0Y1_HUMAN|Unreviewed]SubName: Full=Growth hormone-regulated TBC protein 1 {ECO:0000313|Ensembl:ENSP00000483734};"]
[79794,"'C12orf49'",685,722,703.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005576///extracellular region","GO:0005515///protein binding",null,"IPR019352///Uncharacterised protein family UPF0454","[CL049_HUMAN|Reviewed]RecName: Full=UPF0454 protein C12orf49; Flags: Precursor;+++[A0A024RBQ8_HUMAN|Unreviewed]SubName: Full=Chromosome 12 open reading frame 49, isoform CRA_a {ECO:0000313|EMBL:EAW98089.1};+++[F8VPB4_HUMAN|Unreviewed]SubName: Full=UPF0454 protein C12orf49 {ECO:0000313|Ensembl:ENSP00000446478};+++[F8VVN2_HUMAN|Unreviewed]SubName: Full=UPF0454 protein C12orf49 {ECO:0000313|Ensembl:ENSP00000449151};+++[H0YHS8_HUMAN|Unreviewed]SubName: Full=UPF0454 protein C12orf49 {ECO:0000313|Ensembl:ENSP00000447722}; Flags: Fragment;"]
[79813,"'EHMT1'",763,813,788,"00310///Lysine degradation+++04211///Longevity regulating pathway","H00907///Kleefstra syndrome",null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005694///chromosome+++GO:0016021///integral component of membrane+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0070742///C2H2 zinc finger domain binding+++GO:0002039///p53 binding+++GO:0046872///metal ion binding+++GO:0016279///protein-lysine N-methyltransferase activity+++GO:0046974///histone methyltransferase activity (H3-K9 specific)+++GO:0008270///zinc ion binding+++GO:0008168///methyltransferase activity+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046976///histone methyltransferase activity (H3-K27 specific)+++GO:0016740///transferase activity+++GO:0005515///protein binding","GO:0032259///methylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0018027///peptidyl-lysine dimethylation+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0006306///DNA methylation+++GO:0060992///response to fungicide+++GO:0034968///histone lysine methylation+++GO:0016571///histone methylation+++GO:0006325///chromatin organization+++GO:0070734///histone H3-K27 methylation+++GO:0045995///regulation of embryonic development+++GO:0051567///histone H3-K9 methylation+++GO:0018026///peptidyl-lysine monomethylation+++GO:0045892///negative regulation of transcription, DNA-templated","IPR020683///Ankyrin repeat-containing domain+++IPR038035///Histone-lysine N-methyltransferase EHMT1+++IPR007728///Pre-SET domain+++IPR001214///SET domain+++IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily","[EHMT1_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase EHMT1; EC=2.1.1.-; EC=2.1.1.43; AltName: Full=Euchromatic histone-lysine N-methyltransferase 1; Short=Eu-HMTase1; AltName: Full=G9a-like protein 1; Short=GLP; Short=GLP1; AltName: Full=Histone H3-K9 methyltransferase 5; Short=H3-K9-HMTase 5; AltName: Full=Lysine N-methyltransferase 1D;+++[A0A0C4DGF8_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000436107}; Flags: Fragment;+++[A0A0D9SEP2_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000485878}; Flags: Fragment;+++[A0A0D9SEQ1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000485900}; Flags: Fragment;+++[A0A0D9SER3_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000485933}; Flags: Fragment;+++[A0A0D9SER9_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000485947}; Flags: Fragment;+++[A0A0D9SEY2_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000486127}; Flags: Fragment;+++[A0A0D9SF38_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000486261}; Flags: Fragment;+++[A0A0D9SFD7_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000486503};+++[A0A0D9SFG7_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000486580}; Flags: Fragment;+++[A0A0D9SFM6_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000486748};+++[A0A0D9SFS4_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000486857}; Flags: Fragment;+++[A0A0D9SFX4_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000486969}; Flags: Fragment;+++[A0A1B0GTP4_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000489786}; Flags: Fragment;+++[A0A1B0GU48_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000489961}; Flags: Fragment;+++[A0A1B0GUD1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000490056};+++[A0A1B0GV09_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000490328};+++[A0A1B0GV89_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000490417}; Flags: Fragment;+++[A0A1B0GVZ8_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000490714}; Flags: Fragment;+++[A0A1B0GW12_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000490732};+++[A0A1B0GW79_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000490815}; Flags: Fragment;+++[A0A1B0GWF6_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000490907}; Flags: Fragment;+++[A0A1W2PPZ7_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase EHMT1 {ECO:0000313|Ensembl:ENSP00000491823}; Flags: Fragment;+++[A0PJE0_HUMAN|Unreviewed]SubName: Full=EHMT1 protein {ECO:0000313|EMBL:AAH25772.1}; Flags: Fragment;+++[Q71M33_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein FP13812 {ECO:0000313|EMBL:AAQ04808.1};"]
[79814,"'AGMAT'",32.95,26,29.475,"01100///Metabolic pathways+++00330///Arginine and proline metabolism","H00057///Parkinson's disease (PD)","M00133///Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine","R01157///Agmatine amidinohydrolase   Agmatine + H2O <=> Putrescine + Urea","GO:0005739///mitochondrion","GO:0008783///agmatinase activity+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0016813///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines","GO:0008295///spermidine biosynthetic process+++GO:0009446///putrescine biosynthetic process+++GO:0033388///putrescine biosynthetic process from arginine+++GO:0097055///agmatine biosynthetic process","IPR006035///Ureohydrolase+++IPR020855///Ureohydrolase, manganese-binding site+++IPR023696///Ureohydrolase domain superfamily+++IPR005925///Agmatinase-related","[SPEB_HUMAN|Reviewed]RecName: Full=Agmatinase, mitochondrial; EC=3.5.3.11 {ECO:0000269|PubMed:11914032}; AltName: Full=Agmatine ureohydrolase; Short=AUH; Flags: Precursor;+++[A0A024QZ78_HUMAN|Unreviewed]SubName: Full=Agmatine ureohydrolase (Agmatinase), isoform CRA_a {ECO:0000313|EMBL:EAW51738.1};"]
[79831,"'KDM8'",59,38,48.5,{"$nulls":4},"GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0051213///dioxygenase activity+++GO:0008233///peptidase activity+++GO:0003682///chromatin binding+++GO:0016787///hydrolase activity+++GO:0016491///oxidoreductase activity+++GO:0032452///histone demethylase activity+++GO:0046872///metal ion binding+++GO:0051864///histone demethylase activity (H3-K36 specific)+++GO:0005515///protein binding","GO:0045893///positive regulation of transcription, DNA-templated+++GO:0055114///oxidation-reduction process+++GO:0007049///cell cycle+++GO:0006508///proteolysis+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0070544///histone H3-K36 demethylation","IPR003347///JmjC domain","[KDM8_HUMAN|Reviewed]RecName: Full=JmjC domain-containing protein 5 {ECO:0000305}; EC=1.14.11.27; EC=3.4.-.-; AltName: Full=Jumonji domain-containing protein 5; AltName: Full=Lysine-specific demethylase 8;+++[A0A0S2Z5P4_HUMAN|Unreviewed]SubName: Full=Jumonji domain containing 5 isoform 3 {ECO:0000313|EMBL:ALQ34245.1}; Flags: Fragment;+++[A0A0S2Z5P8_HUMAN|Unreviewed]SubName: Full=Jumonji domain containing 5 isoform 2 {ECO:0000313|EMBL:ALQ34244.1}; Flags: Fragment;+++[A0A0S2Z5T1_HUMAN|Unreviewed]SubName: Full=Jumonji domain containing 5 {ECO:0000313|EMBL:EAW55759.1}; SubName: Full=Jumonji domain containing 5 isoform 1 {ECO:0000313|EMBL:ALQ34243.1}; Flags: Fragment;+++[H3BM39_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000454215}; Flags: Fragment;+++[H3BPT5_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000455463}; Flags: Fragment;+++[H3BR76_HUMAN|Unreviewed]SubName: Full=JmjC domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000456107}; Flags: Fragment;"]
[79848,"'CSPP1'",136,93,114.5,"04144///Endocytosis","H00530///Joubert syndrome",null,null,"GO:0005813///centrosome+++GO:0000922///spindle pole+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0005874///microtubule","GO:0005515///protein binding","GO:0032467///positive regulation of cytokinesis+++GO:0051781///positive regulation of cell division","IPR026708///Centrosome and spindle pole associated protein 1","[CSPP1_HUMAN|Reviewed]RecName: Full=Centrosome and spindle pole-associated protein 1;+++[E5RGA5_HUMAN|Unreviewed]SubName: Full=Centrosome and spindle pole-associated protein 1 {ECO:0000313|Ensembl:ENSP00000428793};+++[E5RI67_HUMAN|Unreviewed]SubName: Full=Centrosome and spindle pole-associated protein 1 {ECO:0000313|Ensembl:ENSP00000429546}; Flags: Fragment;+++[F2Z2M5_HUMAN|Unreviewed]SubName: Full=Centrosome and spindle pole-associated protein 1 {ECO:0000313|Ensembl:ENSP00000428694};+++[Q9H688_HUMAN|Unreviewed]SubName: Full=cDNA: FLJ22490 fis, clone HRC10983 {ECO:0000313|EMBL:BAB15375.1};"]
[79871,"'RPAP2'",72,71,71.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016591///RNA polymerase II, holoenzyme","GO:0043175///RNA polymerase core enzyme binding+++GO:0046872///metal ion binding+++GO:0004722///protein serine/threonine phosphatase activity+++GO:0005515///protein binding+++GO:0008420///RNA polymerase II CTD heptapeptide repeat phosphatase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0016787///hydrolase activity","GO:0042795///snRNA transcription by RNA polymerase II+++GO:0009301///snRNA transcription+++GO:0070940///dephosphorylation of RNA polymerase II C-terminal domain","IPR039693///Rtr1/RPAP2+++IPR038534///Rtr1/RPAP2 domain superfamily+++IPR007308///Rtr1/RPAP2 domain","[RPAP2_HUMAN|Reviewed]RecName: Full=Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2; EC=3.1.3.16; AltName: Full=RNA polymerase II-associated protein 2;"]
[79888,"'LPCAT1'",815,801,808,"01100///Metabolic pathways+++00565///Ether lipid metabolism+++00564///Glycerophospholipid metabolism",null,null,"R03437///Acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine 2-O-acetyltransferase   Acetyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine+++R09036///acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol+++R01318///Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphocholine <=> CoA + Phosphatidylcholine+++R03438///Acyl-CoA:1-alkyl-sn-glycero-3-phosphocholine O-acyltransferase   Acyl-CoA + 1-Organyl-2-lyso-sn-glycero-3-phosphocholine <=> CoA + 1-Radyl-2-acyl-sn-glycero-3-phosphocholine","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0035577///azurophil granule membrane+++GO:0016021///integral component of membrane+++GO:0005811///lipid droplet","GO:0005509///calcium ion binding+++GO:0016746///transferase activity, transferring acyl groups+++GO:0047192///1-alkylglycerophosphocholine O-acetyltransferase activity+++GO:0047191///1-alkylglycerophosphocholine O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016740///transferase activity+++GO:0047184///1-acylglycerophosphocholine O-acyltransferase activity+++GO:0047159///1-alkenylglycerophosphocholine O-acyltransferase activity+++GO:0046872///metal ion binding","GO:0036151///phosphatidylcholine acyl-chain remodeling+++GO:0006654///phosphatidic acid biosynthetic process+++GO:2001246///negative regulation of phosphatidylcholine biosynthetic process+++GO:0006644///phospholipid metabolic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0006629///lipid metabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0043129///surfactant homeostasis+++GO:0060041///retina development in camera-type eye+++GO:0043312///neutrophil degranulation+++GO:0008654///phospholipid biosynthetic process+++GO:0006656///phosphatidylcholine biosynthetic process","IPR011992///EF-hand domain pair+++IPR002123///Phospholipid/glycerol acyltransferase+++IPR002048///EF-hand domain","[PCAT1_HUMAN|Reviewed]RecName: Full=Lysophosphatidylcholine acyltransferase 1; Short=LPC acyltransferase 1; Short=LPCAT-1; Short=LysoPC acyltransferase 1; EC=2.3.1.23; AltName: Full=1-acylglycerophosphocholine O-acyltransferase; AltName: Full=1-alkylglycerophosphocholine O-acetyltransferase; EC=2.3.1.67; AltName: Full=Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; Short=Acetyl-CoA:lyso-PAF acetyltransferase; Short=Lyso-PAF acetyltransferase; Short=LysoPAFAT; AltName: Full=Acyltransferase-like 2; AltName: Full=Phosphonoformate immuno-associated protein 3;+++[A0A0G2JQ62_HUMAN|Unreviewed]SubName: Full=Lysophosphatidylcholine acyltransferase 1 {ECO:0000313|Ensembl:ENSP00000485019}; Flags: Fragment;+++[A0A0G2JRI7_HUMAN|Unreviewed]SubName: Full=Lysophosphatidylcholine acyltransferase 1 {ECO:0000313|Ensembl:ENSP00000486797};+++[D3DTC2_HUMAN|Unreviewed]SubName: Full=Acyltransferase like 2, isoform CRA_a {ECO:0000313|EMBL:EAX08156.1};"]
[79906,"'MORN1'",36,26,31,"04140///Autophagy - animal+++04146///Peroxisome+++04137///Mitophagy - animal","H00177///Adrenoleukodystrophy, neonatal (NALD)+++H00205///Peroxisome biogenesis disorder+++H01342///Zellweger syndrome (ZS)",{"$nulls":5},"IPR003409///MORN motif","[MORN1_HUMAN|Reviewed]RecName: Full=MORN repeat-containing protein 1;+++[B4DRE3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60334, highly similar to MORN repeat-containing protein 1 {ECO:0000313|EMBL:BAG61255.1};+++[Q5T088_HUMAN|Unreviewed]SubName: Full=MORN repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000390261}; Flags: Fragment;+++[U3KQS9_HUMAN|Unreviewed]SubName: Full=MORN repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000476189}; Flags: Fragment;"]
[79932,"'KIAA0319L'",2501.95,2834.63,2668.29,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding","GO:0007010///cytoskeleton organization+++GO:0022604///regulation of cell morphogenesis+++GO:0007275///multicellular organism development","IPR029865///Dyslexia-associated protein KIAA0319-like protein+++IPR035986///PKD domain superfamily+++IPR022409///PKD/Chitinase domain+++IPR013980///MANSC domain+++IPR000601///PKD domain+++IPR013783///Immunoglobulin-like fold","[K319L_HUMAN|Reviewed]RecName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000305|PubMed:20697954}; AltName: Full=Adeno-associated virus receptor {ECO:0000303|PubMed:26814968}; Short=AAVR {ECO:0000303|PubMed:26814968};+++[B1AN15_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000407576}; Flags: Fragment;+++[B4DYG9_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000420369}; SubName: Full=cDNA FLJ55397 {ECO:0000313|EMBL:BAG63731.1}; SubName: Full=cDNA, FLJ79151 {ECO:0000313|EMBL:BAH14623.1};+++[C9J519_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000362363};+++[C9JQ56_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000420226}; Flags: Fragment;+++[C9JVB2_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000419396}; Flags: Fragment;+++[E7EN73_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000395883}; Flags: Fragment;+++[F8WAW2_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000417411};+++[H0Y4S8_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319-like protein {ECO:0000313|Ensembl:ENSP00000393862}; Flags: Fragment;+++[L8EB66_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0319L {ECO:0000313|EMBL:CCQ43723.1};"]
[79957,"'PAQR6'",27,29,28,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0008289///lipid binding+++GO:0005496///steroid binding+++GO:0038023///signaling receptor activity","GO:0048545///response to steroid hormone","IPR004254///AdipoR/Haemolysin-III-related","[PAQR6_HUMAN|Reviewed]RecName: Full=Membrane progestin receptor delta {ECO:0000303|PubMed:23763432}; Short=mPR delta {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone P4 receptor delta {ECO:0000303|PubMed:23763432}; AltName: Full=Membrane progesterone receptor delta {ECO:0000303|PubMed:23763432}; AltName: Full=Progesterone and adipoQ receptor family member 6; AltName: Full=Progestin and adipoQ receptor family member 6 {ECO:0000303|PubMed:16044242};+++[B4DJ42_HUMAN|Unreviewed]SubName: Full=Membrane progestin receptor delta {ECO:0000313|Ensembl:ENSP00000482685}; SubName: Full=cDNA FLJ53340, highly similar to Homo sapiens progestin and adipoQ receptor family member VI (PAQR6), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG58704.1};+++[K9J961_HUMAN|Unreviewed]SubName: Full=Progestin and adipoQ receptor family member VI variant 3 {ECO:0000313|EMBL:ACO54887.1};+++[K9J969_HUMAN|Unreviewed]SubName: Full=Progestin and adipoQ receptor family member VI variant 5 {ECO:0000313|EMBL:ACO54889.1};+++[K9J974_HUMAN|Unreviewed]SubName: Full=Progestin and adipoQ receptor family member VI variant 4 {ECO:0000313|EMBL:ACO54888.1};+++[Q5TCK5_HUMAN|Unreviewed]SubName: Full=Membrane progestin receptor delta {ECO:0000313|Ensembl:ENSP00000341926}; Flags: Fragment;+++[Q5TCK7_HUMAN|Unreviewed]SubName: Full=Progestin and adipoQ receptor family member VI, isoform CRA_a {ECO:0000313|EMBL:EAW52975.1}; SubName: Full=cDNA FLJ54068, highly similar to Progestin and adipoQ receptor family member 6 {ECO:0000313|EMBL:BAG57469.1};+++[Q5TCK8_HUMAN|Unreviewed]SubName: Full=Progestin and adipoQ receptor family member VI, isoform CRA_f {ECO:0000313|EMBL:EAW52981.1}; SubName: Full=cDNA FLJ52547, highly similar to Progestin and adipoQ receptor family member 6 {ECO:0000313|EMBL:BAG58703.1};+++[Q6IQ11_HUMAN|Unreviewed]SubName: Full=PAQR6 protein {ECO:0000313|EMBL:AAH71623.1}; Flags: Fragment;+++[Q7Z4Q8_HUMAN|Unreviewed]SubName: Full=Membrane progestin receptor delta {ECO:0000313|Ensembl:ENSP00000443167}; SubName: Full=Progestin and adipoQ receptor family member VI, isoform CRA_e {ECO:0000313|EMBL:EAW52980.1};"]
[79982,"'DNAJB14'",189,286,237.5,"04662///B cell receptor signaling pathway",{"$nulls":3},"GO:0031965///nuclear membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005634///nucleus+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030544///Hsp70 protein binding","GO:0051085///chaperone cofactor-dependent protein refolding+++GO:0034622///cellular protein-containing complex assembly","IPR015399///Domain of unknown function DUF1977, DnaJ-like+++IPR036869///Chaperone J-domain superfamily+++IPR018253///DnaJ domain, conserved site+++IPR001623///DnaJ domain","[DJB14_HUMAN|Reviewed]RecName: Full=DnaJ homolog subfamily B member 14 {ECO:0000312|HGNC:HGNC:25881};+++[A0A024RDI9_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily B, member 14, isoform CRA_b {ECO:0000313|EMBL:EAX06116.1};+++[A0A087WWX2_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 14 {ECO:0000313|Ensembl:ENSP00000480565};+++[F2Z2L8_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 14 {ECO:0000313|Ensembl:ENSP00000390023};+++[H7BZG5_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 14 {ECO:0000313|Ensembl:ENSP00000389471}; Flags: Fragment;+++[H7BZK3_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 14 {ECO:0000313|Ensembl:ENSP00000390019}; Flags: Fragment;+++[H7C494_HUMAN|Unreviewed]SubName: Full=DnaJ homolog subfamily B member 14 {ECO:0000313|Ensembl:ENSP00000416179}; Flags: Fragment;"]
[80008,"'TMEM156'",13,10,11.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0006310///DNA recombination","IPR029374///TMEM156 protein","[TM156_HUMAN|Reviewed]RecName: Full=Transmembrane protein 156;+++[A0A024R9T9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW92906.1};+++[J3KNV8_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 156 {ECO:0000313|Ensembl:ENSP00000343758}; Flags: Fragment;"]
[80031,"'SEMA6D'",21,17,19,"04360///Axon guidance",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0009986///cell surface+++GO:0005615///extracellular space+++GO:0005794///Golgi apparatus","GO:0038191///neuropilin binding+++GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding","GO:0030154///cell differentiation+++GO:0014912///negative regulation of smooth muscle cell migration+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0001755///neural crest cell migration+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0021591///ventricular system development+++GO:0050919///negative chemotaxis+++GO:0030335///positive regulation of cell migration+++GO:0030517///negative regulation of axon extension","IPR002165///Plexin repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR027231///Semaphorin+++IPR001627///Sema domain+++IPR016201///PSI domain+++IPR036352///Sema domain superfamily","[SEM6D_HUMAN|Reviewed]RecName: Full=Semaphorin-6D; Flags: Precursor;+++[A0A185QE25_HUMAN|Unreviewed]SubName: Full=Semaphorin-6D isoform 8 {ECO:0000313|EMBL:AKA64472.1};+++[H0YL82_HUMAN|Unreviewed]SubName: Full=Semaphorin-6D {ECO:0000313|Ensembl:ENSP00000453097}; Flags: Fragment;+++[H0YM97_HUMAN|Unreviewed]SubName: Full=Semaphorin-6D {ECO:0000313|Ensembl:ENSP00000453518}; Flags: Fragment;+++[H0YMA6_HUMAN|Unreviewed]SubName: Full=Semaphorin-6D {ECO:0000313|Ensembl:ENSP00000453530}; Flags: Fragment;+++[H0YMP7_HUMAN|Unreviewed]SubName: Full=Semaphorin-6D {ECO:0000313|Ensembl:ENSP00000453689}; Flags: Fragment;+++[H0YMV0_HUMAN|Unreviewed]SubName: Full=Semaphorin-6D {ECO:0000313|Ensembl:ENSP00000453755}; Flags: Fragment;"]
[801,"'CALM1'",2921,2800,2860.5,"04270///Vascular smooth muscle contraction+++05010///Alzheimer's disease+++04915///Estrogen signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04625///C-type lectin receptor signaling pathway+++04922///Glucagon signaling pathway+++05152///Tuberculosis+++04020///Calcium signaling pathway+++04970///Salivary secretion+++05163///Human cytomegalovirus infection+++05031///Amphetamine addiction+++04744///Phototransduction+++04016///MAPK signaling pathway - plant+++04070///Phosphatidylinositol signaling system+++04925///Aldosterone synthesis and secretion+++04015///Rap1 signaling pathway+++04740///Olfactory transduction+++05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04924///Renin secretion+++04720///Long-term potentiation+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04745///Phototransduction - fly+++04971///Gastric acid secretion+++04014///Ras signaling pathway+++04916///Melanogenesis+++05133///Pertussis+++05034///Alcoholism+++04371///Apelin signaling pathway+++04728///Dopaminergic synapse+++04626///Plant-pathogen interaction+++04218///Cellular senescence+++04261///Adrenergic signaling in cardiomyocytes+++05214///Glioma+++04022///cGMP-PKG signaling pathway+++04114///Oocyte meiosis+++04921///Oxytocin signaling pathway+++04024///cAMP signaling pathway+++04912///GnRH signaling pathway+++04910///Insulin signaling pathway+++04722///Neurotrophin signaling pathway+++04713///Circadian entrainment","H01019///Catecholaminergic polymorphic ventricular tachycardia+++H00720///Long QT syndrome",null,null,"GO:0043209///myelin sheath+++GO:0005819///spindle+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0031982///vesicle+++GO:0034704///calcium channel complex+++GO:1902494///catalytic complex+++GO:0030426///growth cone+++GO:0005829///cytosol+++GO:0043005///neuron projection+++GO:0005576///extracellular region+++GO:0005876///spindle microtubule+++GO:0031966///mitochondrial membrane+++GO:0030672///synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0008076///voltage-gated potassium channel complex+++GO:0030017///sarcomere+++GO:0005856///cytoskeleton+++GO:0000922///spindle pole+++GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0032991///protein-containing complex","GO:0047485///protein N-terminus binding+++GO:0008179///adenylate cyclase binding+++GO:0031800///type 3 metabotropic glutamate receptor binding+++GO:0019904///protein domain specific binding+++GO:0019855///calcium channel inhibitor activity+++GO:0048306///calcium-dependent protein binding+++GO:0043548///phosphatidylinositol 3-kinase binding+++GO:0072542///protein phosphatase activator activity+++GO:0016301///kinase activity+++GO:0030235///nitric-oxide synthase regulator activity+++GO:0010856///adenylate cyclase activator activity+++GO:0031432///titin binding+++GO:0031997///N-terminal myristoylation domain binding+++GO:0044325///ion channel binding+++GO:0005509///calcium ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0050998///nitric-oxide synthase binding+++GO:0019901///protein kinase binding+++GO:0097718///disordered domain specific binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0008440///inositol-1,4,5-trisphosphate 3-kinase activity","GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:0001975///response to amphetamine+++GO:0005513///detection of calcium ion+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0055117///regulation of cardiac muscle contraction+++GO:0016310///phosphorylation+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0043647///inositol phosphate metabolic process+++GO:2000300///regulation of synaptic vesicle exocytosis+++GO:0000165///MAPK cascade+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0019722///calcium-mediated signaling+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0007190///activation of adenylate cyclase activity+++GO:0075206///positive regulation by host of symbiont cAMP-mediated signal transduction+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:0021762///substantia nigra development+++GO:0051412///response to corticosterone+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0051186///cofactor metabolic process+++GO:0002027///regulation of heart rate+++GO:0006936///muscle contraction+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0051592///response to calcium ion+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0060314///regulation of ryanodine-sensitive calcium-release channel activity+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0090150///establishment of protein localization to membrane+++GO:0002576///platelet degranulation+++GO:0090151///establishment of protein localization to mitochondrial membrane+++GO:0032465///regulation of cytokinesis+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0043388///positive regulation of DNA binding+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0007223///Wnt signaling pathway, calcium modulating pathway+++GO:1900242///regulation of synaptic vesicle endocytosis","IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain+++IPR039030///Calmodulin+++IPR018247///EF-Hand 1, calcium-binding site","[CALM1_HUMAN|Reviewed]RecName: Full=Calmodulin-1 {ECO:0000312|HGNC:HGNC:1442};+++[CALM2_HUMAN|Reviewed]RecName: Full=Calmodulin-2 {ECO:0000312|HGNC:HGNC:1445};+++[CALM3_HUMAN|Reviewed]RecName: Full=Calmodulin-3 {ECO:0000312|HGNC:HGNC:1449};+++[B4DJ51_HUMAN|Unreviewed]SubName: Full=Calmodulin 1 (Phosphorylase kinase, delta), isoform CRA_a {ECO:0000313|EMBL:EAW81427.1}; SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_b {ECO:0000313|EMBL:EAW57426.1}; SubName: Full=Epididymis secretory protein Li 72 {ECO:0000313|EMBL:ACI46002.1}; SubName: Full=cDNA FLJ61744, highly similar to Calmodulin {ECO:0000313|EMBL:BAG58713.1};+++[E7ETZ0_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000403491};+++[G3V226_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000450425};+++[G3V361_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000451062}; Flags: Fragment;+++[G3V479_HUMAN|Unreviewed]SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000451646};+++[M0QZ52_HUMAN|Unreviewed]SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_d {ECO:0000313|EMBL:EAW57428.1}; SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000486402}; SubName: Full=Calmodulin-2 {ECO:0000313|Ensembl:ENSP00000486952}; SubName: Full=Calmodulin-3 {ECO:0000313|Ensembl:ENSP00000470308};"]
[80135,"'RPF1'",309,297,303,{"$nulls":4},"GO:0030687///preribosome, large subunit precursor+++GO:0005730///nucleolus","GO:0042134///rRNA primary transcript binding+++GO:0003723///RNA binding","GO:0000027///ribosomal large subunit assembly+++GO:0000460///maturation of 5.8S rRNA+++GO:0000470///maturation of LSU-rRNA","IPR007109///Brix domain","[RPF1_HUMAN|Reviewed]RecName: Full=Ribosome production factor 1; AltName: Full=Brix domain-containing protein 5; AltName: Full=Ribosome biogenesis protein RPF1;+++[X6R7Q1_HUMAN|Unreviewed]SubName: Full=Ribosome production factor 1 {ECO:0000313|Ensembl:ENSP00000359690};"]
[80169,"'CTC1'",176,186,181,"04137///Mitophagy - animal+++04140///Autophagy - animal+++05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005694///chromosome+++GO:0000784///nuclear chromosome, telomeric region+++GO:1990879///CST complex+++GO:0000781///chromosome, telomeric region+++GO:0005634///nucleus","GO:0003697///single-stranded DNA binding+++GO:0042162///telomeric DNA binding+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0016233///telomere capping+++GO:0045740///positive regulation of DNA replication+++GO:0032211///negative regulation of telomere maintenance via telomerase+++GO:0071425///hematopoietic stem cell proliferation+++GO:0035264///multicellular organism growth+++GO:0090399///replicative senescence+++GO:0006974///cellular response to DNA damage stimulus+++GO:0048539///bone marrow development+++GO:0000723///telomere maintenance+++GO:0007568///aging+++GO:0048536///spleen development+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0048538///thymus development+++GO:0051276///chromosome organization+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0010833///telomere maintenance via telomere lengthening","IPR029156///CST complex subunit CTC1","[CTC1_HUMAN|Reviewed]RecName: Full=CST complex subunit CTC1; AltName: Full=Conserved telomere maintenance component 1; AltName: Full=HBV DNAPTP1-transactivated protein B;+++[A0A2R8Y574_HUMAN|Unreviewed]SubName: Full=CST complex subunit CTC1 {ECO:0000313|Ensembl:ENSP00000494323};+++[D3U719_HUMAN|Unreviewed]SubName: Full=Conserved telomere capping protein 1 {ECO:0000313|EMBL:ACY71127.1};+++[J3KSR1_HUMAN|Unreviewed]SubName: Full=CST complex subunit CTC1 {ECO:0000313|Ensembl:ENSP00000462607}; Flags: Fragment;+++[J3KSZ1_HUMAN|Unreviewed]SubName: Full=CST complex subunit CTC1 {ECO:0000313|Ensembl:ENSP00000462720}; Flags: Fragment;+++[J3QKT7_HUMAN|Unreviewed]SubName: Full=CST complex subunit CTC1 {ECO:0000313|Ensembl:ENSP00000463230}; Flags: Fragment;"]
[80199,"'FUZ'",171,161,166,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0042995///cell projection+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0019956///chemokine binding","GO:0008589///regulation of smoothened signaling pathway+++GO:0001843///neural tube closure+++GO:0070098///chemokine-mediated signaling pathway+++GO:0048704///embryonic skeletal system morphogenesis+++GO:0030030///cell projection organization+++GO:0001942///hair follicle development+++GO:0090301///negative regulation of neural crest formation+++GO:0006954///inflammatory response+++GO:2000314///negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation+++GO:0060271///cilium assembly+++GO:0030336///negative regulation of cell migration+++GO:0008285///negative regulation of cell proliferation+++GO:0015031///protein transport+++GO:0001736///establishment of planar polarity+++GO:0007275///multicellular organism development+++GO:1905515///non-motile cilium assembly+++GO:0010172///embryonic body morphogenesis+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0045724///positive regulation of cilium assembly","IPR026069///Fuzzy protein","[FUZZY_HUMAN|Reviewed]RecName: Full=Protein fuzzy homolog;+++[A0A024QZF7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW52542.1};+++[A0A1L5BXN3_HUMAN|Unreviewed]SubName: Full=DARC/ACKR1 {ECO:0000313|EMBL:APL98094.1}; Flags: Fragment;+++[E9PK12_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000431731};+++[E9PKJ4_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000433492};+++[E9PLA3_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000431388};+++[E9PS25_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000432148}; Flags: Fragment;+++[G5E9A4_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000366296};+++[M0QYI7_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000469856};+++[M0QYX9_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000470155};+++[M0QZY8_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000470863};+++[M0R0M0_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000471319};+++[M0R1D4_HUMAN|Unreviewed]SubName: Full=Protein fuzzy homolog {ECO:0000313|Ensembl:ENSP00000471793}; Flags: Fragment;+++[Q3L2S9_HUMAN|Unreviewed]SubName: Full=Duffy blood group antigen {ECO:0000313|EMBL:AAW71991.1}; Flags: Fragment;+++[Q3LSS9_HUMAN|Unreviewed]SubName: Full=Duffy antigen/chemokine receptor isoform a {ECO:0000313|EMBL:AET81036.1}; SubName: Full=Duffy blood group {ECO:0000313|EMBL:ABA10434.1}; SubName: Full=HCG39425 {ECO:0000313|EMBL:EAW52791.1};+++[Q3LST0_HUMAN|Unreviewed]SubName: Full=Duffy antigen/chemokine receptor isoform b {ECO:0000313|EMBL:AET81035.1}; SubName: Full=Duffy blood group {ECO:0000313|EMBL:ABA10433.1};+++[Q5Y7A3_HUMAN|Unreviewed]SubName: Full=Duffy antigen chemokine receptor {ECO:0000313|EMBL:AFN67103.1}; SubName: Full=Duffy antigen/chemokine receptor isoform a {ECO:0000313|EMBL:AET81024.1}; SubName: Full=Duffy blood group {ECO:0000313|EMBL:AAU47279.1};+++[Q5Y7A4_HUMAN|Unreviewed]SubName: Full=Duffy antigen/chemokine receptor isoform b {ECO:0000313|EMBL:AET81023.1}; SubName: Full=Duffy blood group {ECO:0000313|EMBL:AAU47278.1};+++[Q8IWP5_HUMAN|Unreviewed]SubName: Full=Duffy antigen {ECO:0000313|EMBL:AAO11657.1};"]
[80221,"'ACSF2'",172,154,163,{"$nulls":4},"GO:0005759///mitochondrial matrix+++GO:0005739///mitochondrion","GO:0016874///ligase activity+++GO:0003996///acyl-CoA ligase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0003824///catalytic activity","GO:0006629///lipid metabolic process+++GO:0006631///fatty acid metabolic process+++GO:0006637///acyl-CoA metabolic process","IPR025110///AMP-binding enzyme, C-terminal domain+++IPR000873///AMP-dependent synthetase/ligase+++IPR020845///AMP-binding, conserved site","[ACSF2_HUMAN|Reviewed]RecName: Full=Acyl-CoA synthetase family member 2, mitochondrial; EC=6.2.1.-; Flags: Precursor;+++[B4DTB9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50666, weakly similar to Long-chain-fatty-acid--CoA ligase {ECO:0000313|EMBL:BAG61931.1};+++[D6RF15_HUMAN|Unreviewed]SubName: Full=Acyl-CoA synthetase family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000426730};+++[D6RF87_HUMAN|Unreviewed]SubName: Full=Acyl-CoA synthetase family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000424842}; Flags: Fragment;+++[E7EN53_HUMAN|Unreviewed]SubName: Full=Acyl-CoA synthetase family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000425332};+++[E9PF16_HUMAN|Unreviewed]SubName: Full=Acyl-CoA synthetase family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000425964};+++[H0Y8N1_HUMAN|Unreviewed]SubName: Full=Acyl-CoA synthetase family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000421558}; Flags: Fragment;+++[H0Y8Y5_HUMAN|Unreviewed]SubName: Full=Acyl-CoA synthetase family member 2, mitochondrial {ECO:0000313|Ensembl:ENSP00000422546}; Flags: Fragment;"]
[80258,"'EFHC2'",0,5,2.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0005971///ribonucleoside-diphosphate reductase complex","GO:0005509///calcium ion binding+++GO:0005515///protein binding","GO:1990830///cellular response to leukemia inhibitory factor","IPR006602///Uncharacterised domain DM10+++IPR002048///EF-hand domain+++IPR011992///EF-hand domain pair+++IPR010554///Domain of unknown function DUF1126","[EFHC2_HUMAN|Reviewed]RecName: Full=EF-hand domain-containing family member C2;"]
[80301,"'PLEKHO2'",198,219,208.5,{"$nulls":4},"GO:0005576///extracellular region+++GO:1904813///ficolin-1-rich granule lumen",null,"GO:0043312///neutrophil degranulation","IPR001849///Pleckstrin homology domain+++IPR011993///PH-like domain superfamily","[PKHO2_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family O member 2; Short=PH domain-containing family O member 2; AltName: Full=Pleckstrin homology domain-containing family Q member 1; Short=PH domain-containing family Q member 1;"]
[80319,"'CXXC4'",14,11,12.5,"04310///Wnt signaling pathway",{"$nulls":3},"GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm","GO:0030165///PDZ domain binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding+++GO:0003677///DNA binding","GO:0016055///Wnt signaling pathway+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0007352///zygotic specification of dorsal/ventral axis","IPR002857///Zinc finger, CXXC-type","[CXXC4_HUMAN|Reviewed]RecName: Full=CXXC-type zinc finger protein 4; AltName: Full=Inhibition of the Dvl and axin complex protein;+++[J9JIF5_HUMAN|Unreviewed]SubName: Full=CXXC-type zinc finger protein 4 {ECO:0000313|Ensembl:ENSP00000378248};"]
[8034,"'SLC25A16'",119,138,128.5,{"$nulls":4},"GO:0005622///intracellular+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0005829///cytosol","GO:0015291///secondary active transmembrane transporter activity+++GO:0016787///hydrolase activity+++GO:0015297///antiporter activity+++GO:0016810///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds+++GO:0008270///zinc ion binding+++GO:0022857///transmembrane transporter activity+++GO:0046872///metal ion binding+++GO:0008892///guanine deaminase activity","GO:0046098///guanine metabolic process+++GO:0055085///transmembrane transport+++GO:0007399///nervous system development+++GO:0006147///guanine catabolic process+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0009108///coenzyme biosynthetic process+++GO:0006195///purine nucleotide catabolic process+++GO:0006839///mitochondrial transport","IPR023395///Mitochondrial carrier domain superfamily+++IPR040062///Mitochondrial carrier domain protein+++IPR002067///Mitochondrial carrier protein+++IPR018108///Mitochondrial substrate/solute carrier+++IPR002167///Graves disease carrier protein","[GDC_HUMAN|Reviewed]RecName: Full=Graves disease carrier protein; Short=GDC; AltName: Full=Graves disease autoantigen; Short=GDA; AltName: Full=Mitochondrial solute carrier protein homolog; AltName: Full=Solute carrier family 25 member 16;+++[B4DHV9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59258, highly similar to Grave disease carrier protein {ECO:0000313|EMBL:BAG58271.1};+++[B4DPV4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60777, highly similar to Grave disease carrier protein {ECO:0000313|EMBL:BAG60716.1};+++[V9GY06_HUMAN|Unreviewed]SubName: Full=Graves disease carrier protein {ECO:0000313|Ensembl:ENSP00000476283};+++[V9GYA5_HUMAN|Unreviewed]SubName: Full=Graves disease carrier protein {ECO:0000313|Ensembl:ENSP00000476555};+++[V9GYB8_HUMAN|Unreviewed]SubName: Full=Graves disease carrier protein {ECO:0000313|Ensembl:ENSP00000476587}; Flags: Fragment;+++[V9GZ24_HUMAN|Unreviewed]SubName: Full=Graves disease carrier protein {ECO:0000313|Ensembl:ENSP00000477328}; Flags: Fragment;"]
[805,"'CALM2'",2957,2383,2670,"05163///Human cytomegalovirus infection+++04744///Phototransduction+++04921///Oxytocin signaling pathway+++04916///Melanogenesis+++04713///Circadian entrainment+++04971///Gastric acid secretion+++04625///C-type lectin receptor signaling pathway+++05031///Amphetamine addiction+++04114///Oocyte meiosis+++04720///Long-term potentiation+++05418///Fluid shear stress and atherosclerosis+++04020///Calcium signaling pathway+++04022///cGMP-PKG signaling pathway+++04750///Inflammatory mediator regulation of TRP channels+++04016///MAPK signaling pathway - plant+++04924///Renin secretion+++04626///Plant-pathogen interaction+++04070///Phosphatidylinositol signaling system+++04270///Vascular smooth muscle contraction+++05034///Alcoholism+++04371///Apelin signaling pathway+++04970///Salivary secretion+++05152///Tuberculosis+++04218///Cellular senescence+++04722///Neurotrophin signaling pathway+++04745///Phototransduction - fly+++04015///Rap1 signaling pathway+++04261///Adrenergic signaling in cardiomyocytes+++04740///Olfactory transduction+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04925///Aldosterone synthesis and secretion+++04910///Insulin signaling pathway+++04922///Glucagon signaling pathway+++05010///Alzheimer's disease+++04728///Dopaminergic synapse+++05133///Pertussis+++04014///Ras signaling pathway+++05214///Glioma+++04024///cAMP signaling pathway+++04915///Estrogen signaling pathway+++05200///Pathways in cancer+++04912///GnRH signaling pathway","H01019///Catecholaminergic polymorphic ventricular tachycardia+++H00720///Long QT syndrome",null,null,"GO:0005815///microtubule organizing center+++GO:0034704///calcium channel complex+++GO:0005876///spindle microtubule+++GO:0043209///myelin sheath+++GO:0030017///sarcomere+++GO:0000922///spindle pole+++GO:0031982///vesicle+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0008076///voltage-gated potassium channel complex+++GO:1902494///catalytic complex+++GO:0005813///centrosome+++GO:0032991///protein-containing complex+++GO:0005819///spindle+++GO:0005886///plasma membrane","GO:0072542///protein phosphatase activator activity+++GO:0031997///N-terminal myristoylation domain binding+++GO:0005515///protein binding+++GO:0010856///adenylate cyclase activator activity+++GO:0019904///protein domain specific binding+++GO:0044325///ion channel binding+++GO:0008179///adenylate cyclase binding+++GO:0019855///calcium channel inhibitor activity+++GO:0019901///protein kinase binding+++GO:0097718///disordered domain specific binding+++GO:0046872///metal ion binding+++GO:0031432///titin binding+++GO:0005509///calcium ion binding+++GO:0043539///protein serine/threonine kinase activator activity","GO:0010881///regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion+++GO:0021762///substantia nigra development+++GO:0060316///positive regulation of ryanodine-sensitive calcium-release channel activity+++GO:0007186///G protein-coupled receptor signaling pathway+++GO:0051592///response to calcium ion+++GO:0071902///positive regulation of protein serine/threonine kinase activity+++GO:0010880///regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum+++GO:1901844///regulation of cell communication by electrical coupling involved in cardiac conduction+++GO:0002027///regulation of heart rate+++GO:0019722///calcium-mediated signaling+++GO:0075206///positive regulation by host of symbiont cAMP-mediated signal transduction+++GO:0055117///regulation of cardiac muscle contraction+++GO:0032465///regulation of cytokinesis+++GO:0060315///negative regulation of ryanodine-sensitive calcium-release channel activity+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0043388///positive regulation of DNA binding+++GO:0010801///negative regulation of peptidyl-threonine phosphorylation+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0051343///positive regulation of cyclic-nucleotide phosphodiesterase activity+++GO:0005513///detection of calcium ion+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0032516///positive regulation of phosphoprotein phosphatase activity","IPR002048///EF-hand domain+++IPR039030///Calmodulin+++IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair","[CALM1_HUMAN|Reviewed]RecName: Full=Calmodulin-1 {ECO:0000312|HGNC:HGNC:1442};+++[CALM2_HUMAN|Reviewed]RecName: Full=Calmodulin-2 {ECO:0000312|HGNC:HGNC:1445};+++[CALM3_HUMAN|Reviewed]RecName: Full=Calmodulin-3 {ECO:0000312|HGNC:HGNC:1449};+++[B4DJ51_HUMAN|Unreviewed]SubName: Full=Calmodulin 1 (Phosphorylase kinase, delta), isoform CRA_a {ECO:0000313|EMBL:EAW81427.1}; SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_b {ECO:0000313|EMBL:EAW57426.1}; SubName: Full=Epididymis secretory protein Li 72 {ECO:0000313|EMBL:ACI46002.1}; SubName: Full=cDNA FLJ61744, highly similar to Calmodulin {ECO:0000313|EMBL:BAG58713.1};+++[E7EMB3_HUMAN|Unreviewed]SubName: Full=Calmodulin-2 {ECO:0000313|Ensembl:ENSP00000387065};+++[F8WBR5_HUMAN|Unreviewed]SubName: Full=Calmodulin-2 {ECO:0000313|Ensembl:ENSP00000406112};+++[H0Y7A7_HUMAN|Unreviewed]SubName: Full=Calmodulin-2 {ECO:0000313|Ensembl:ENSP00000411440}; Flags: Fragment;+++[Q96HY3_HUMAN|Unreviewed]SubName: Full=CALM1 protein {ECO:0000313|EMBL:AAH07965.1}; SubName: Full=Calmodulin 2 (Phosphorylase kinase, delta), isoform CRA_a {ECO:0000313|EMBL:EAX00220.1}; SubName: Full=Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_a {ECO:0000313|EMBL:EAW57425.1}; SubName: Full=Calmodulin-1 {ECO:0000313|Ensembl:ENSP00000442853}; SubName: Full=Calmodulin-3 {ECO:0000313|Ensembl:ENSP00000375785}; SubName: Full=LP7057 protein {ECO:0000313|EMBL:AAO86731.1};"]
[80731,"'THSD7B'",5,3,4,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0000166///nucleotide binding+++GO:0003697///single-stranded DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0003727///single-stranded RNA binding+++GO:0042802///identical protein binding+++GO:0046872///metal ion binding+++GO:0009036///type II site-specific deoxyribonuclease activity","GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006310///DNA recombination+++GO:0032197///transposition, RNA-mediated+++GO:0032199///reverse transcription involved in RNA-mediated transposition","IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR000884///Thrombospondin type-1 (TSP1) repeat","[THS7B_HUMAN|Reviewed]RecName: Full=Thrombospondin type-1 domain-containing protein 7B; Flags: Precursor;+++[C9JKN6_HUMAN|Unreviewed]SubName: Full=Thrombospondin type-1 domain-containing protein 7B {ECO:0000313|Ensembl:ENSP00000413841};+++[E7EM75_HUMAN|Unreviewed]SubName: Full=Thrombospondin type-1 domain-containing protein 7B {ECO:0000313|Ensembl:ENSP00000387145};+++[Q8WUV0_HUMAN|Unreviewed]SubName: Full=THSD7B protein {ECO:0000313|EMBL:AAH19344.1}; Flags: Fragment;+++[R4GMU2_HUMAN|Unreviewed]SubName: Full=Thrombospondin type-1 domain-containing protein 7B {ECO:0000313|Ensembl:ENSP00000473349};"]
[80762,"'NDFIP1'",1677,1649,1663,{"$nulls":4},"GO:0048471///perinuclear region of cytoplasm+++GO:0042995///cell projection+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0043005///neuron projection+++GO:0030425///dendrite+++GO:0010008///endosome membrane+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005938///cell cortex+++GO:0045202///synapse+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0050699///WW domain binding","GO:0032713///negative regulation of interleukin-4 production+++GO:0048302///regulation of isotype switching to IgG isotypes+++GO:0002829///negative regulation of type 2 immune response+++GO:0032410///negative regulation of transporter activity+++GO:0045619///regulation of lymphocyte differentiation+++GO:0042130///negative regulation of T cell proliferation+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006879///cellular iron ion homeostasis+++GO:0030001///metal ion transport+++GO:0002761///regulation of myeloid leukocyte differentiation+++GO:0045732///positive regulation of protein catabolic process+++GO:0007034///vacuolar transport+++GO:0051224///negative regulation of protein transport+++GO:0050728///negative regulation of inflammatory response+++GO:0010629///negative regulation of gene expression+++GO:0048294///negative regulation of isotype switching to IgE isotypes+++GO:0031398///positive regulation of protein ubiquitination","IPR019325///NEDD4/Bsd2","[NFIP1_HUMAN|Reviewed]RecName: Full=NEDD4 family-interacting protein 1; AltName: Full=Breast cancer-associated protein SGA-1M; AltName: Full=NEDD4 WW domain-binding protein 5; AltName: Full=Putative MAPK-activating protein PM13; AltName: Full=Putative NF-kappa-B-activating protein 164; AltName: Full=Putative NFKB and MAPK-activating protein;"]
[80816,"'ASXL3'",26,35,30.5,null,"H02047///Bohring-Opitz syndrome+++H01481///Myelodysplastic syndrome (MDS)",null,null,"GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0035517///PR-DUB complex","GO:0042975///peroxisome proliferator activated receptor binding+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003682///chromatin binding","GO:0009887///animal organ morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated","IPR024811///Polycomb protein ASX/ASX-like+++IPR028020///ASX homology domain+++IPR007759///HB1/Asxl, restriction endonuclease HTH domain+++IPR024818///ASX-like protein 3+++IPR026905///Protein ASX-like, PHD domain","[ASXL3_HUMAN|Reviewed]RecName: Full=Putative Polycomb group protein ASXL3; AltName: Full=Additional sex combs-like protein 3;+++[A0A2R8Y461_HUMAN|Unreviewed]SubName: Full=Putative Polycomb group protein ASXL3 {ECO:0000313|Ensembl:ENSP00000493665}; Flags: Fragment;+++[K7EJ76_HUMAN|Unreviewed]SubName: Full=Putative Polycomb group protein ASXL3 {ECO:0000313|Ensembl:ENSP00000465053};+++[K7ELG8_HUMAN|Unreviewed]SubName: Full=Putative Polycomb group protein ASXL3 {ECO:0000313|Ensembl:ENSP00000466073};+++[K7EMU6_HUMAN|Unreviewed]SubName: Full=Putative Polycomb group protein ASXL3 {ECO:0000313|Ensembl:ENSP00000466655};"]
[80852,"'GRIP2'",16,13,14.5,null,"H00687///Fraser syndrome",null,null,"GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0045211///postsynaptic membrane+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0005737///cytoplasm","GO:0030159///receptor signaling complex scaffold activity","GO:0014824///artery smooth muscle contraction+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0015031///protein transport+++GO:0007219///Notch signaling pathway+++GO:0045777///positive regulation of blood pressure+++GO:0099003///vesicle-mediated transport in synapse","IPR036034///PDZ superfamily+++IPR001478///PDZ domain+++IPR030029///Glutamate receptor-interacting protein 2","[GRIP2_HUMAN|Reviewed]RecName: Full=Glutamate receptor-interacting protein 2 {ECO:0000305}; Short=GRIP-2;+++[A0A087WX15_HUMAN|Unreviewed]SubName: Full=Glutamate receptor-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000480660};+++[A0A087WYB3_HUMAN|Unreviewed]SubName: Full=Glutamate receptor-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000481670}; Flags: Fragment;+++[A0A1B0GUL8_HUMAN|Unreviewed]SubName: Full=Glutamate receptor-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000490164}; Flags: Fragment;+++[A0A1B0GWJ3_HUMAN|Unreviewed]SubName: Full=Glutamate receptor-interacting protein 2 {ECO:0000313|Ensembl:ENSP00000490949};"]
[81,"'ACTN4'",56095,51763,53929,"05322///Systemic lupus erythematosus+++04810///Regulation of actin cytoskeleton+++04510///Focal adhesion+++05146///Amoebiasis+++04530///Tight junction+++05203///Viral carcinogenesis+++04520///Adherens junction+++04670///Leukocyte transendothelial migration","H00626///Focal segmental glomerulosclerosis+++H01740///Macrothrombocytopenia",null,null,"GO:0032991///protein-containing complex+++GO:0030018///Z disc+++GO:0005829///cytosol+++GO:0005911///cell-cell junction+++GO:0031143///pseudopodium+++GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0031093///platelet alpha granule lumen+++GO:1990904///ribonucleoprotein complex+++GO:0030054///cell junction+++GO:0005903///brush border+++GO:0015629///actin cytoskeleton+++GO:0005634///nucleus+++GO:0005925///focal adhesion+++GO:0005856///cytoskeleton+++GO:0043005///neuron projection+++GO:0016604///nuclear body+++GO:0005576///extracellular region+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0030863///cortical cytoskeleton+++GO:0001725///stress fiber+++GO:0005622///intracellular","GO:0047485///protein N-terminus binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0042803///protein homodimerization activity+++GO:0051015///actin filament binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0035257///nuclear hormone receptor binding+++GO:0044877///protein-containing complex binding+++GO:0003713///transcription coactivator activity+++GO:0031490///chromatin DNA binding+++GO:0003723///RNA binding+++GO:0005509///calcium ion binding+++GO:0003779///actin binding+++GO:0001882///nucleoside binding+++GO:0005178///integrin binding+++GO:0042974///retinoic acid receptor binding+++GO:0044325///ion channel binding","GO:0070830///bicellular tight junction assembly+++GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:1902396///protein localization to bicellular tight junction+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:1900025///negative regulation of substrate adhesion-dependent cell spreading+++GO:0051272///positive regulation of cellular component movement+++GO:1903506///regulation of nucleic acid-templated transcription+++GO:0048384///retinoic acid receptor signaling pathway+++GO:0030335///positive regulation of cell migration+++GO:0030050///vesicle transport along actin filament+++GO:0048549///positive regulation of pinocytosis+++GO:0002576///platelet degranulation+++GO:0015031///protein transport+++GO:0042981///regulation of apoptotic process+++GO:0035357///peroxisome proliferator activated receptor signaling pathway+++GO:0032417///positive regulation of sodium:proton antiporter activity+++GO:0051271///negative regulation of cellular component movement+++GO:0001666///response to hypoxia+++GO:0051017///actin filament bundle assembly","IPR014837///EF-hand, Ca insensitive+++IPR011992///EF-hand domain pair+++IPR018247///EF-Hand 1, calcium-binding site+++IPR001589///Actinin-type actin-binding domain, conserved site+++IPR001715///Calponin homology domain+++IPR036872///CH domain superfamily+++IPR002048///EF-hand domain+++IPR018159///Spectrin/alpha-actinin+++IPR029637///Alpha-actinin-4+++IPR002017///Spectrin repeat","[ACTN4_HUMAN|Reviewed]RecName: Full=Alpha-actinin-4 {ECO:0000305}; AltName: Full=Non-muscle alpha-actinin 4 {ECO:0000303|PubMed:10656685};+++[A0A0S2Z3C0_HUMAN|Unreviewed]SubName: Full=Actinin alpha 4 isoform 3 {ECO:0000313|EMBL:ALQ33341.1}; Flags: Fragment;+++[A0A0S2Z3G1_HUMAN|Unreviewed]SubName: Full=Actinin alpha 4 isoform 4 {ECO:0000313|EMBL:ALQ33342.1};+++[A0A0S2Z3G9_HUMAN|Unreviewed]SubName: Full=Actinin alpha 4 isoform 1 {ECO:0000313|EMBL:ALQ33339.1}; Flags: Fragment;+++[A0A0S2Z3X3_HUMAN|Unreviewed]SubName: Full=Actinin alpha 4 isoform 2 {ECO:0000313|EMBL:ALQ33340.1}; Flags: Fragment;+++[F5GXS2_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-4 {ECO:0000313|Ensembl:ENSP00000411187};+++[H7C144_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-4 {ECO:0000313|Ensembl:ENSP00000398393}; Flags: Fragment;+++[K7EJH8_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-4 {ECO:0000313|Ensembl:ENSP00000465176}; Flags: Fragment;+++[K7EP19_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-4 {ECO:0000313|Ensembl:ENSP00000467190}; Flags: Fragment;+++[Q96BG6_HUMAN|Unreviewed]SubName: Full=ACTN4 protein {ECO:0000313|EMBL:AAH15620.2}; Flags: Fragment;"]
[8125,"'ANP32A'",1124,974,1049,{"$nulls":4},"GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0042393///histone binding+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006913///nucleocytoplasmic transport+++GO:0043488///regulation of mRNA stability+++GO:0035556///intracellular signal transduction","IPR003603///U2A'/phosphoprotein 32 family A, C-terminal+++IPR032675///Leucine-rich repeat domain superfamily+++IPR001611///Leucine-rich repeat","[AN32A_HUMAN|Reviewed]RecName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member A; AltName: Full=Acidic nuclear phosphoprotein pp32; Short=pp32; AltName: Full=Leucine-rich acidic nuclear protein; Short=LANP; AltName: Full=Mapmodulin; AltName: Full=Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; AltName: Full=Putative HLA-DR-associated protein I; Short=PHAPI;+++[H0YN26_HUMAN|Unreviewed]SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member A {ECO:0000313|Ensembl:ENSP00000453838};+++[H7BZ09_HUMAN|Unreviewed]SubName: Full=Acidic leucine-rich nuclear phosphoprotein 32 family member A {ECO:0000313|Ensembl:ENSP00000386496};+++[Q08AJ6_HUMAN|Unreviewed]SubName: Full=ANP32A protein {ECO:0000313|EMBL:AAI25144.1};+++[Q3KPI8_HUMAN|Unreviewed]SubName: Full=ANP32A protein {ECO:0000313|EMBL:AAI06720.1};+++[Q6PKH8_HUMAN|Unreviewed]SubName: Full=ANP32A protein {ECO:0000313|EMBL:AAH00608.1}; Flags: Fragment;"]
[81490,"'PTDSS2'",1187,1114,1150.5,"01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism+++01100///Metabolic pathways",null,null,"R07376///L-1-phosphatidylethanolamine:L-serine phosphatidyltransferase   Phosphatidylethanolamine + L-Serine <=> Phosphatidylserine + Ethanolamine","GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0003882///CDP-diacylglycerol-serine O-phosphatidyltransferase activity+++GO:0016740///transferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006659///phosphatidylserine biosynthetic process+++GO:0006629///lipid metabolic process","IPR004277///Phosphatidyl serine synthase","[PTSS2_HUMAN|Reviewed]RecName: Full=Phosphatidylserine synthase 2; Short=PSS-2; Short=PtdSer synthase 2; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme II;+++[A0A024RC97_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 2, isoform CRA_a {ECO:0000313|EMBL:EAX02329.1};+++[A0A0J9YWQ2_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 2 {ECO:0000313|Ensembl:ENSP00000488064}; Flags: Fragment;+++[E9PLE4_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 2 {ECO:0000313|Ensembl:ENSP00000435168};+++[E9PS47_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 2 {ECO:0000313|Ensembl:ENSP00000432100};"]
[81556,"'INTS14'",269,238,253.5,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0032039///integrator complex+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm",null,"GO:0034472///snRNA 3'-end processing+++GO:0042795///snRNA transcription by RNA polymerase II","IPR002035///von Willebrand factor, type A+++IPR036465///von Willebrand factor A-like domain superfamily+++IPR039841///Integrator complex subunit 14","[INT14_HUMAN|Reviewed]RecName: Full=Integrator complex subunit 14 {ECO:0000312|HGNC:HGNC:25372}; AltName: Full=von Willebrand factor A domain-containing protein 9;+++[B4DJL6_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000457624}; SubName: Full=cDNA FLJ55475 {ECO:0000313|EMBL:BAG58878.1};+++[B4DVT3_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000396314}; SubName: Full=cDNA FLJ50705 {ECO:0000313|EMBL:BAG62795.1};+++[B4DWZ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50723 {ECO:0000313|EMBL:BAG63205.1};+++[H3BMK7_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000454425}; Flags: Fragment;+++[H3BN95_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000454743}; Flags: Fragment;+++[H3BNR6_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000454972};+++[H3BP17_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000455105};+++[H3BRY6_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000456460};+++[H3BT02_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000456956}; Flags: Fragment;+++[H3BV25_HUMAN|Unreviewed]SubName: Full=Integrator complex subunit 14 {ECO:0000313|Ensembl:ENSP00000457922}; Flags: Fragment;"]
[81578,"'COL21A1'",0,4,2,"04974///Protein digestion and absorption",{"$nulls":3},"GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0062023///collagen-containing extracellular matrix+++GO:0005788///endoplasmic reticulum lumen+++GO:0005737///cytoplasm+++GO:0005581///collagen trimer+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix","GO:0030020///extracellular matrix structural constituent conferring tensile strength","GO:0003429///growth plate cartilage chondrocyte morphogenesis","IPR008160///Collagen triple helix repeat+++IPR001791///Laminin G domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR002035///von Willebrand factor, type A+++IPR036465///von Willebrand factor A-like domain superfamily","[COLA1_HUMAN|Reviewed]RecName: Full=Collagen alpha-1(XXI) chain; Flags: Precursor;+++[A0A158RFW1_HUMAN|Unreviewed]SubName: Full=Alpha 1 type XXI collagen {ECO:0000313|EMBL:ACJ66843.1}; Flags: Precursor;+++[A6PVD9_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XXI) chain {ECO:0000313|Ensembl:ENSP00000359853}; Flags: Fragment;+++[B3KU30_HUMAN|Unreviewed]SubName: Full=cDNA FLJ39125 fis, clone NTONG2007034, highly similar to Homo sapiens collagen, type XXI, alpha 1 (COL21A1), mRNA {ECO:0000313|EMBL:BAG53292.1};+++[B7ZLK3_HUMAN|Unreviewed]SubName: Full=COL21A1 protein {ECO:0000313|EMBL:AAI43866.1};+++[F5GZK2_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XXI) chain {ECO:0000313|Ensembl:ENSP00000444384};+++[H0Y4C9_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XXI) chain {ECO:0000313|Ensembl:ENSP00000390958}; Flags: Fragment;+++[H0YDH6_HUMAN|Unreviewed]SubName: Full=Collagen alpha-1(XXI) chain {ECO:0000313|Ensembl:ENSP00000433624}; Flags: Fragment;"]
[81616,"'ACSBG2'",6,3,4.5,"00071///Fatty acid degradation+++00061///Fatty acid biosynthesis+++01212///Fatty acid metabolism+++01100///Metabolic pathways+++03320///PPAR signaling pathway+++04920///Adipocytokine signaling pathway",null,"M00086///beta-Oxidation, acyl-CoA synthesis","R01280///Palmitate:CoA ligase (AMP-forming)   ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate","GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0016020///membrane","GO:0031957///very long-chain fatty acid-CoA ligase activity+++GO:0047617///acyl-CoA hydrolase activity+++GO:0016874///ligase activity+++GO:0102391///decanoate-CoA ligase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004467///long-chain fatty acid-CoA ligase activity+++GO:0003824///catalytic activity","GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0007275///multicellular organism development+++GO:0006629///lipid metabolic process+++GO:0007283///spermatogenesis+++GO:0001676///long-chain fatty acid metabolic process+++GO:0030154///cell differentiation+++GO:0006631///fatty acid metabolic process","IPR020845///AMP-binding, conserved site+++IPR000873///AMP-dependent synthetase/ligase","[ACBG2_HUMAN|Reviewed]RecName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2; EC=6.2.1.3; AltName: Full=Acyl-CoA synthetase bubblegum family member 2; AltName: Full=Bubblegum-related protein; AltName: Full=PRTD-NY3;+++[A0A140VJD4_HUMAN|Unreviewed]SubName: Full=Testicular tissue protein Li 8 {ECO:0000313|EMBL:AEE60921.1};+++[B4DYU1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58343, highly similar to Homo sapiens acyl-CoA synthetase bubblegum family member 2 (ACSBG2), mRNA {ECO:0000313|EMBL:BAG63853.1};+++[K7EKE4_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2 {ECO:0000313|Ensembl:ENSP00000465581}; Flags: Fragment;+++[K7EL11_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2 {ECO:0000313|Ensembl:ENSP00000465870}; Flags: Fragment;+++[K7EMB4_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2 {ECO:0000313|Ensembl:ENSP00000466434}; Flags: Fragment;+++[K7ERT0_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2 {ECO:0000313|Ensembl:ENSP00000468394}; Flags: Fragment;+++[K7ESC8_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2 {ECO:0000313|Ensembl:ENSP00000468652}; Flags: Fragment;+++[K7ESF1_HUMAN|Unreviewed]SubName: Full=Long-chain-fatty-acid--CoA ligase ACSBG2 {ECO:0000313|Ensembl:ENSP00000468684};"]
[81691,"'REXO5'",9,11,10,"03008///Ribosome biogenesis in eukaryotes",null,null,"R01176///Butanoate:CoA ligase (AMP-forming) ATP + Butanoic acid + CoA <=> AMP + Diphosphate + Butanoyl-CoA","GO:0070062///extracellular exosome+++GO:0005730///nucleolus","GO:0003676///nucleic acid binding+++GO:0004527///exonuclease activity+++GO:0004518///nuclease activity+++GO:0016787///hydrolase activity+++GO:0003723///RNA binding","GO:0090305///nucleic acid phosphodiester bond hydrolysis","IPR034922///RNA exonuclease 1-like, exonuclease domain+++IPR036397///Ribonuclease H superfamily+++IPR013520///Exonuclease, RNase T/DNA polymerase III+++IPR035979///RNA-binding domain superfamily+++IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR012337///Ribonuclease H-like superfamily","[REXO5_HUMAN|Reviewed]RecName: Full=RNA exonuclease 5 {ECO:0000312|HGNC:HGNC:24661}; EC=3.1.-.-; AltName: Full=Exonuclease NEF-sp;+++[A0A024R390_HUMAN|Unreviewed]SubName: Full=Exonuclease NEF-sp, isoform CRA_a {ECO:0000313|EMBL:EAW66841.1};+++[H3BM72_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000454262}; Flags: Fragment;+++[H3BPB2_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000455233}; Flags: Fragment;+++[H3BQ98_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000455677}; Flags: Fragment;+++[H3BQP3_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000455867}; Flags: Fragment;+++[H3BR13_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456030}; Flags: Fragment;+++[H3BRC7_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456182};+++[H3BRG1_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456227};+++[H3BSC5_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456643}; Flags: Fragment;+++[H3BSE4_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000456666}; Flags: Fragment;+++[H3BUT7_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000457789}; Flags: Fragment;+++[H3BV93_HUMAN|Unreviewed]SubName: Full=RNA exonuclease 5 {ECO:0000313|Ensembl:ENSP00000458004}; Flags: Fragment;"]
[81794,"'ADAMTS10'",322,333,327.5,null,"H00673///Weill-Marchesani syndrome",null,null,"GO:0001527///microfibril+++GO:0062023///collagen-containing extracellular matrix+++GO:0005576///extracellular region","GO:0008233///peptidase activity+++GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0008237///metallopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0046872///metal ion binding","GO:0008150///biological_process+++GO:0006508///proteolysis","IPR036383///Thrombospondin type-1 (TSP1) repeat superfamily+++IPR010909///PLAC+++IPR000884///Thrombospondin type-1 (TSP1) repeat+++IPR013273///ADAMTS/ADAMTS-like+++IPR010294///ADAM-TS Spacer 1+++IPR002870///Peptidase M12B, propeptide+++IPR001590///Peptidase M12B, ADAM/reprolysin+++IPR024079///Metallopeptidase, catalytic domain superfamily","[ATS10_HUMAN|Reviewed]RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 10; Short=ADAM-TS 10; Short=ADAM-TS10; Short=ADAMTS-10; EC=3.4.24.-; Flags: Precursor;+++[A0A0A0MQW6_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 10 {ECO:0000313|Ensembl:ENSP00000270328};+++[L0R574_HUMAN|Unreviewed]SubName: Full=Alternative protein ADAMTS10 {ECO:0000313|EMBL:CCO13669.1};+++[M0QY12_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 10 {ECO:0000313|Ensembl:ENSP00000469516};+++[M0QY36_HUMAN|Unreviewed]SubName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 10 {ECO:0000313|Ensembl:ENSP00000469559};+++[Q59FE5_HUMAN|Unreviewed]SubName: Full=A disintegrin-like and metalloprotease (Reprolysin type) with thrombospondin type 1 motif, 10 preproprotein variant {ECO:0000313|EMBL:BAD92752.1}; Flags: Fragment;+++[Q6ZN14_HUMAN|Unreviewed]SubName: Full=cDNA FLJ16524 fis, clone OCBBF2003327, moderately similar to ADAM-TS 6 {ECO:0000313|EMBL:BAD18561.1};"]
[81857,"'MED25'",2738,2693,2715.5,null,"H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0005654///nucleoplasm+++GO:0044798///nuclear transcription factor complex","GO:0042974///retinoic acid receptor binding+++GO:0046965///retinoid X receptor binding+++GO:0008134///transcription factor binding","GO:0035563///positive regulation of chromatin binding+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:2001178///positive regulation of mediator complex assembly+++GO:0071158///positive regulation of cell cycle arrest+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR021397///Mediator complex, subunit Med25, synapsin 1+++IPR021419///Mediator complex, subunit Med25, von Willebrand factor type A+++IPR021394///Mediator complex, subunit Med25, PTOV domain+++IPR038196///PTOV domain superfamily+++IPR021406///Mediator complex, subunit Med25, NR box+++IPR036465///von Willebrand factor A-like domain superfamily","[MED25_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 25; AltName: Full=Activator interaction domain-containing protein 1; AltName: Full=Activator-recruited cofactor 92 kDa component; Short=ARC92; AltName: Full=Mediator complex subunit 25; AltName: Full=p78;+++[A0A087WTR5_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 25 {ECO:0000313|Ensembl:ENSP00000478074};+++[A0A087WW16_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 25 {ECO:0000313|Ensembl:ENSP00000479851};+++[A0A087WYW9_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 25 {ECO:0000313|Ensembl:ENSP00000482155};+++[B9TX29_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i2 {ECO:0000313|EMBL:ACB88861.1}; Flags: Fragment;+++[B9TX31_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i4 {ECO:0000313|EMBL:ACB88863.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 25 {ECO:0000313|Ensembl:ENSP00000480731};+++[B9TX32_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i5 {ECO:0000313|EMBL:ACB88864.1}; Flags: Fragment;+++[B9TX33_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i6 {ECO:0000313|EMBL:ACB88865.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 25 {ECO:0000313|Ensembl:ENSP00000482659};+++[B9TX34_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i7 {ECO:0000313|EMBL:ACB88866.1}; Flags: Fragment;+++[B9TX35_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i8 {ECO:0000313|EMBL:ACB88867.1}; Flags: Fragment;+++[B9TX36_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i9 {ECO:0000313|EMBL:ACB88868.1};+++[B9TX37_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i10 {ECO:0000313|EMBL:ACB88869.1};+++[B9TX38_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i11 {ECO:0000313|EMBL:ACB88870.1}; Flags: Fragment;+++[B9TX39_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i12 {ECO:0000313|EMBL:ACB88871.1}; Flags: Fragment;+++[B9TX40_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i13 {ECO:0000313|EMBL:ACB88872.1};+++[B9TX41_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i14 {ECO:0000313|EMBL:ACB88873.1};+++[B9TX42_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i15 {ECO:0000313|EMBL:ACB88874.1};+++[B9TX43_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i16 {ECO:0000313|EMBL:ACB88875.1};+++[B9TX44_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i17 {ECO:0000313|EMBL:ACB88876.1};+++[B9TX45_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i18 {ECO:0000313|EMBL:ACB88877.1};+++[B9TX46_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i19 {ECO:0000313|EMBL:ACB88878.1};+++[B9TX47_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i20 {ECO:0000313|EMBL:ACB88879.1};+++[B9TX48_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED25 variant MED25_i21 {ECO:0000313|EMBL:ACB88880.1};+++[M0QYR4_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 25 {ECO:0000313|Ensembl:ENSP00000470027}; Flags: Fragment;+++[M0QZQ2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 25 {ECO:0000313|Ensembl:ENSP00000470692}; Flags: Fragment;"]
[8192,"'CLPP'",1498,1238,1368,"04112///Cell cycle - Caulobacter+++04212///Longevity regulating pathway - worm","H02095///Perrault syndrome",null,null,"GO:0005759///mitochondrial matrix+++GO:0009368///endopeptidase Clp complex+++GO:0005739///mitochondrion","GO:0004176///ATP-dependent peptidase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0051117///ATPase binding+++GO:0008233///peptidase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0051603///proteolysis involved in cellular protein catabolic process+++GO:0006508///proteolysis+++GO:0051260///protein homooligomerization+++GO:0006515///protein quality control for misfolded or incompletely synthesized proteins","IPR029045///ClpP/crotonase-like domain superfamily+++IPR001907///ATP-dependent Clp protease proteolytic subunit+++IPR018215///ClpP, Ser active site+++IPR033135///ClpP, histidine active site+++IPR023562///Clp protease proteolytic subunit /Translocation-enhancing protein TepA","[CLPP_HUMAN|Reviewed]RecName: Full=ATP-dependent Clp protease proteolytic subunit, mitochondrial; EC=3.4.21.92; AltName: Full=Endopeptidase Clp; Flags: Precursor;+++[A0A2R8YEF5_HUMAN|Unreviewed]SubName: Full=ATP-dependent Clp protease proteolytic subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000494298}; Flags: Fragment;+++[M0QXE9_HUMAN|Unreviewed]RecName: Full=ATP-dependent Clp protease proteolytic subunit {ECO:0000256|RuleBase:RU003567}; Flags: Fragment;+++[M0QYV5_HUMAN|Unreviewed]SubName: Full=ATP-dependent Clp protease proteolytic subunit, mitochondrial {ECO:0000313|Ensembl:ENSP00000470098}; Flags: Fragment;+++[M0R208_HUMAN|Unreviewed]RecName: Full=ATP-dependent Clp protease proteolytic subunit {ECO:0000256|RuleBase:RU003567}; EC=3.4.21.92 {ECO:0000256|RuleBase:RU000549};"]
[8214,"'DGCR6'",11.57,0,5.785,{"$nulls":4},"GO:0031012///extracellular matrix+++GO:0005634///nucleus",null,"GO:0009887///animal organ morphogenesis+++GO:0007155///cell adhesion","IPR010849///Gonadal family","[DGCR6_HUMAN|Reviewed]RecName: Full=Protein DGCR6; AltName: Full=DiGeorge syndrome critical region 6;+++[X5D7D2_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region 6 isoform D {ECO:0000313|EMBL:AHW56460.1}; Flags: Fragment;"]
[8242,"'KDM5C'",1234,1469,1351.5,null,"H00658///Syndromic X-linked mental retardation",null,null,"GO:0005654///nucleoplasm+++GO:0035097///histone methyltransferase complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0046872///metal ion binding+++GO:0032453///histone demethylase activity (H3-K4 specific)+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0032452///histone demethylase activity+++GO:0003682///chromatin binding+++GO:0008270///zinc ion binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0051213///dioxygenase activity+++GO:0035064///methylated histone binding+++GO:0003677///DNA binding+++GO:0034647///histone demethylase activity (H3-trimethyl-K4 specific)+++GO:0016491///oxidoreductase activity","GO:0055114///oxidation-reduction process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0048511///rhythmic process+++GO:0006325///chromatin organization+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0034720///histone H3-K4 demethylation+++GO:0034721///histone H3-K4 demethylation, trimethyl-H3-K4-specific","IPR036431///ARID DNA-binding domain superfamily+++IPR001965///Zinc finger, PHD-type+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR019787///Zinc finger, PHD-finger+++IPR004198///Zinc finger, C5HC2-type+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR001606///ARID DNA-binding domain+++IPR013637///Lysine-specific demethylase-like domain+++IPR003347///JmjC domain+++IPR003349///JmjN domain","[KDM5C_HUMAN|Reviewed]RecName: Full=Lysine-specific demethylase 5C; EC=1.14.11.-; AltName: Full=Histone demethylase JARID1C; AltName: Full=Jumonji/ARID domain-containing protein 1C {ECO:0000303|PubMed:19636912}; AltName: Full=Protein SmcX {ECO:0000303|PubMed:19636912}; AltName: Full=Protein Xe169;+++[A6N6J7_HUMAN|Unreviewed]SubName: Full=JARID1C protein {ECO:0000313|EMBL:ABR13544.1};+++[F8W7H7_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5C {ECO:0000313|Ensembl:ENSP00000344004};+++[F8WDK1_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5C {ECO:0000313|Ensembl:ENSP00000409757};+++[F8WF56_HUMAN|Unreviewed]SubName: Full=Lysine-specific demethylase 5C {ECO:0000313|Ensembl:ENSP00000407277};+++[L8E945_HUMAN|Unreviewed]SubName: Full=Alternative protein KDM5C {ECO:0000313|EMBL:CCQ43251.1};"]
[8289,"'ARID1A'",1719,2209,1964,"04714///Thermogenesis+++05225///Hepatocellular carcinoma","H00048///Hepatocellular carcinoma+++H00773///Autosomal dominant mental retardation+++H01403///Coffin-Siris syndrome",null,null,"GO:0071565///nBAF complex+++GO:0071564///npBAF complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0016514///SWI/SNF complex+++GO:0070603///SWI/SNF superfamily-type complex","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0016922///nuclear receptor binding+++GO:0003713///transcription coactivator activity+++GO:0031491///nucleosome binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0055007///cardiac muscle cell differentiation+++GO:0007566///embryo implantation+++GO:0042766///nucleosome mobilization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006338///chromatin remodeling+++GO:0007399///nervous system development+++GO:0060674///placenta blood vessel development+++GO:0030521///androgen receptor signaling pathway+++GO:0001704///formation of primary germ layer+++GO:0003408///optic cup formation involved in camera-type eye development+++GO:0007369///gastrulation+++GO:0006337///nucleosome disassembly+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:0001843///neural tube closure+++GO:0003205///cardiac chamber development+++GO:0019827///stem cell population maintenance+++GO:0006325///chromatin organization+++GO:0030900///forebrain development+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:1901998///toxin transport+++GO:0043044///ATP-dependent chromatin remodeling+++GO:0006344///maintenance of chromatin silencing+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042921///glucocorticoid receptor signaling pathway","IPR001606///ARID DNA-binding domain+++IPR030094///SWI/SNF-like  complex subunit BAF250a+++IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical+++IPR033388///SWI/SNF-like complex subunit BAF250, C-terminal+++IPR036431///ARID DNA-binding domain superfamily+++IPR021906///SWI/SNF-like complex subunit BAF250/Osa","[ARI1A_HUMAN|Reviewed]RecName: Full=AT-rich interactive domain-containing protein 1A; Short=ARID domain-containing protein 1A; AltName: Full=B120; AltName: Full=BRG1-associated factor 250; Short=BAF250; AltName: Full=BRG1-associated factor 250a; Short=BAF250A; AltName: Full=Osa homolog 1; Short=hOSA1; AltName: Full=SWI-like protein; AltName: Full=SWI/SNF complex protein p270; AltName: Full=SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1; AltName: Full=hELD;+++[A0A087WUV6_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000478955};+++[A0A0S2Q0B1_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|EMBL:ALP06203.1};+++[A0A1B0GTU5_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000489842}; Flags: Fragment;+++[A0A1B0GVT5_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000490650}; Flags: Fragment;+++[A4FU79_HUMAN|Unreviewed]SubName: Full=ARID1A protein {ECO:0000313|EMBL:AAI12896.1}; Flags: Fragment;+++[C1KEN7_HUMAN|Unreviewed]SubName: Full=ARID1A {ECO:0000313|EMBL:ACO49592.1}; Flags: Fragment;+++[E9PQW6_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000432473}; Flags: Fragment;+++[H0Y488_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000390317};+++[H0YCU6_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000432368}; Flags: Fragment;+++[H0YEW5_HUMAN|Unreviewed]SubName: Full=AT-rich interactive domain-containing protein 1A {ECO:0000313|Ensembl:ENSP00000436692}; Flags: Fragment;+++[Q4LE49_HUMAN|Unreviewed]SubName: Full=ARID1A variant protein {ECO:0000313|EMBL:BAE06104.1}; Flags: Fragment;"]
[8315,"'BRAP'",274,280,277,"04014///Ras signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0000151///ubiquitin ligase complex","GO:0003676///nucleic acid binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0042802///identical protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0008270///zinc ion binding","GO:0000165///MAPK cascade+++GO:0009968///negative regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0007265///Ras protein signal transduction","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR011422///BRCA1-associated 2+++IPR035979///RNA-binding domain superfamily+++IPR034932///BRAP2, RNA recognition motif+++IPR001607///Zinc finger, UBP-type","[BRAP_HUMAN|Reviewed]RecName: Full=BRCA1-associated protein; EC=2.3.2.27 {ECO:0000269|PubMed:14724641}; AltName: Full=BRAP2; AltName: Full=Impedes mitogenic signal propagation; Short=IMP; AltName: Full=RING finger protein 52; AltName: Full=RING-type E3 ubiquitin transferase BRAP2 {ECO:0000305}; AltName: Full=Renal carcinoma antigen NY-REN-63;+++[Q59H81_HUMAN|Unreviewed]SubName: Full=BRCA1 associated protein variant {ECO:0000313|EMBL:BAD92115.1}; Flags: Fragment;"]
[8317,"'CDC7'",26,27,26.5,"04110///Cell cycle+++04113///Meiosis - yeast+++04111///Cell cycle - yeast",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0072686///mitotic spindle+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0045171///intercellular bridge","GO:0046872///metal ion binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0005515///protein binding","GO:0051301///cell division+++GO:0006468///protein phosphorylation+++GO:0010571///positive regulation of nuclear cell cycle DNA replication+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0006260///DNA replication+++GO:0006270///DNA replication initiation+++GO:0018105///peptidyl-serine phosphorylation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0016310///phosphorylation+++GO:0070317///negative regulation of G0 to G1 transition+++GO:0008284///positive regulation of cell proliferation+++GO:0044770///cell cycle phase transition+++GO:0007049///cell cycle+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0000727///double-strand break repair via break-induced replication","IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site+++IPR017441///Protein kinase, ATP binding site","[CDC7_HUMAN|Reviewed]RecName: Full=Cell division cycle 7-related protein kinase; Short=CDC7-related kinase; Short=HsCdc7; Short=huCdc7; EC=2.7.11.1;+++[B1AMW7_HUMAN|Unreviewed]SubName: Full=Cell division cycle 7-related protein kinase {ECO:0000313|Ensembl:ENSP00000398077}; Flags: Fragment;+++[B2R6V2_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ93132, highly similar to Homo sapiens CDC7 cell division cycle 7 (S. cerevisiae) (CDC7), mRNA {ECO:0000313|EMBL:BAG35599.1};+++[Q6JSD6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 7-like protein 1 {ECO:0000313|EMBL:AAR16187.1}; Flags: Fragment;"]
[8334,"'HIST1H2AC'",300,201,250.5,"04217///Necroptosis+++05322///Systemic lupus erythematosus+++05034///Alcoholism",{"$nulls":3},"GO:0070062///extracellular exosome+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0000786///nucleosome+++GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0003674///molecular_function+++GO:0046982///protein heterodimerization activity","GO:0008285///negative regulation of cell proliferation+++GO:0006325///chromatin organization","IPR009072///Histone-fold+++IPR032458///Histone H2A conserved site+++IPR032454///Histone H2A, C-terminal domain+++IPR002119///Histone H2A+++IPR007125///Histone H2A/H2B/H3","[H2A1C_HUMAN|Reviewed]RecName: Full=Histone H2A type 1-C; AltName: Full=Histone H2A/l;+++[A0A024R017_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};"]
[83444,"'INO80B'",378,326,352,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0031011///Ino80 complex+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0006281///DNA repair+++GO:0006338///chromatin remodeling+++GO:0006310///DNA recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016579///protein deubiquitination","IPR007529///Zinc finger, HIT-type+++IPR029523///INO80 complex, subunit Ies2+++IPR006880///INO80 complex subunit B-like conserved region","[IN80B_HUMAN|Reviewed]RecName: Full=INO80 complex subunit B; AltName: Full=High mobility group AT-hook 1-like 4; AltName: Full=IES2 homolog; Short=hIes2; AltName: Full=PAP-1-associated protein 1; Short=PAPA-1; AltName: Full=Zinc finger HIT domain-containing protein 4;+++[B8ZZ93_HUMAN|Unreviewed]SubName: Full=INO80 complex subunit B {ECO:0000313|Ensembl:ENSP00000387267};+++[B8ZZH7_HUMAN|Unreviewed]SubName: Full=INO80 complex subunit B {ECO:0000313|Ensembl:ENSP00000386937}; Flags: Fragment;+++[C9JKY0_HUMAN|Unreviewed]SubName: Full=INO80 complex subunit B {ECO:0000313|Ensembl:ENSP00000389887}; Flags: Fragment;+++[H7C171_HUMAN|Unreviewed]SubName: Full=INO80 complex subunit B {ECO:0000313|Ensembl:ENSP00000398740}; Flags: Fragment;"]
[83478,"'ARHGAP24'",45,25,35,{"$nulls":4},"GO:0030054///cell junction+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0042995///cell projection+++GO:0005912///adherens junction+++GO:0005925///focal adhesion","GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0001525///angiogenesis+++GO:0030154///cell differentiation+++GO:0043547///positive regulation of GTPase activity+++GO:0007275///multicellular organism development+++GO:0007165///signal transduction","IPR011993///PH-like domain superfamily+++IPR001849///Pleckstrin homology domain+++IPR000198///Rho GTPase-activating protein domain+++IPR008936///Rho GTPase activation protein","[RHG24_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 24; AltName: Full=Filamin-A-associated RhoGAP; Short=FilGAP; AltName: Full=RAC1- and CDC42-specific GTPase-activating protein of 72 kDa; Short=RC-GAP72; AltName: Full=Rho-type GTPase-activating protein 24; AltName: Full=RhoGAP of 73 kDa; AltName: Full=Sarcoma antigen NY-SAR-88; AltName: Full=p73RhoGAP;+++[A0A2X0SFU2_HUMAN|Unreviewed]SubName: Full=ARHGAP24 {ECO:0000313|EMBL:SPT35695.1}; Flags: Fragment;+++[D6RBC2_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 24 {ECO:0000313|Ensembl:ENSP00000424256}; Flags: Fragment;+++[D6RCP5_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 24 {ECO:0000313|Ensembl:ENSP00000425589}; Flags: Fragment;+++[D6RHH1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 24 {ECO:0000313|Ensembl:ENSP00000426105}; Flags: Fragment;"]
[83544,"'DNAL1'",223.75,238.56,231.155,"05016///Huntington's disease","H00564///Primary ciliary dyskinesia",null,null,"GO:0005737///cytoplasm+++GO:0036157///outer dynein arm+++GO:0005856///cytoskeleton+++GO:0030286///dynein complex+++GO:0005874///microtubule+++GO:0042995///cell projection","GO:0003774///motor activity+++GO:0045504///dynein heavy chain binding+++GO:0005515///protein binding+++GO:0043014///alpha-tubulin binding","GO:0036158///outer dynein arm assembly","IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily","[DNAL1_HUMAN|Reviewed]RecName: Full=Dynein light chain 1, axonemal; Short=LC1 {ECO:0000250|UniProtKB:Q9XHH2};+++[G3V2M0_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000450744};+++[G3V389_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000451101}; Flags: Fragment;+++[G3V424_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000451547}; Flags: Fragment;+++[G3V5I4_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000452368}; Flags: Fragment;+++[H0YJD6_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000451264}; Flags: Fragment;+++[H0YM28_HUMAN|Unreviewed]SubName: Full=Dynein light chain 1, axonemal {ECO:0000313|Ensembl:ENSP00000453439}; Flags: Fragment;"]
[836,"'CASP3'",326,285,305.5,"04726///Serotonergic synapse+++05206///MicroRNAs in cancer+++04115///p53 signaling pathway+++05016///Huntington's disease+++05168///Herpes simplex infection+++05010///Alzheimer's disease+++05014///Amyotrophic lateral sclerosis (ALS)+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05145///Toxoplasmosis+++05203///Viral carcinogenesis+++05152///Tuberculosis+++04215///Apoptosis - multiple species+++05416///Viral myocarditis+++05012///Parkinson's disease+++05133///Pertussis+++04932///Non-alcoholic fatty liver disease (NAFLD)+++01524///Platinum drug resistance+++05200///Pathways in cancer+++04010///MAPK signaling pathway+++05165///Human papillomavirus infection+++05222///Small cell lung cancer+++04668///TNF signaling pathway+++04933///AGE-RAGE signaling pathway in diabetic complications+++04210///Apoptosis+++05205///Proteoglycans in cancer+++04657///IL-17 signaling pathway+++04650///Natural killer cell mediated cytotoxicity+++05210///Colorectal cancer+++05161///Hepatitis B+++05134///Legionellosis+++05146///Amoebiasis+++05163///Human cytomegalovirus infection","H02041///Myopia","M00685///Apoptotic machinery",null,"GO:0043025///neuronal cell body+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031264///death-inducing signaling complex+++GO:0005737///cytoplasm+++GO:0045121///membrane raft+++GO:0005654///nucleoplasm","GO:0097153///cysteine-type endopeptidase activity involved in apoptotic process+++GO:0044877///protein-containing complex binding+++GO:0004861///cyclin-dependent protein serine/threonine kinase inhibitor activity+++GO:0016787///hydrolase activity+++GO:0097199///cysteine-type endopeptidase activity involved in apoptotic signaling pathway+++GO:0002020///protease binding+++GO:0004190///aspartic-type endopeptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0097200///cysteine-type endopeptidase activity involved in execution phase of apoptosis+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0004197///cysteine-type endopeptidase activity+++GO:0016005///phospholipase A2 activator activity+++GO:0005123///death receptor binding+++GO:0005515///protein binding+++GO:0008233///peptidase activity","GO:0008627///intrinsic apoptotic signaling pathway in response to osmotic stress+++GO:0007611///learning or memory+++GO:0097190///apoptotic signaling pathway+++GO:0097192///extrinsic apoptotic signaling pathway in absence of ligand+++GO:0009749///response to glucose+++GO:0007605///sensory perception of sound+++GO:0032496///response to lipopolysaccharide+++GO:0016241///regulation of macroautophagy+++GO:0032025///response to cobalt ion+++GO:0030216///keratinocyte differentiation+++GO:0043066///negative regulation of apoptotic process+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0034349///glial cell apoptotic process+++GO:0009411///response to UV+++GO:0035556///intracellular signal transduction+++GO:0001782///B cell homeostasis+++GO:0007507///heart development+++GO:0010038///response to metal ion+++GO:0051384///response to glucocorticoid+++GO:0007413///axonal fasciculation+++GO:0043085///positive regulation of catalytic activity+++GO:0046007///negative regulation of activated T cell proliferation+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0035094///response to nicotine+++GO:0010033///response to organic substance+++GO:0031647///regulation of protein stability+++GO:0030182///neuron differentiation+++GO:0045165///cell fate commitment+++GO:0019221///cytokine-mediated signaling pathway+++GO:0035329///hippo signaling+++GO:0001666///response to hypoxia+++GO:0045736///negative regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0043029///T cell homeostasis+++GO:0006309///apoptotic DNA fragmentation+++GO:0043200///response to amino acid+++GO:0071407///cellular response to organic cyclic compound+++GO:0097194///execution phase of apoptosis+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0032355///response to estradiol+++GO:0016485///protein processing+++GO:0001554///luteolysis+++GO:0009611///response to wounding+++GO:0042060///wound healing+++GO:0046677///response to antibiotic+++GO:0030220///platelet formation+++GO:0072734///cellular response to staurosporine+++GO:0021766///hippocampus development+++GO:0034612///response to tumor necrosis factor+++GO:1902004///positive regulation of amyloid-beta formation+++GO:0071310///cellular response to organic substance+++GO:0014070///response to organic cyclic compound+++GO:0006508///proteolysis+++GO:0030889///negative regulation of B cell proliferation+++GO:0071887///leukocyte apoptotic process+++GO:0051146///striated muscle cell differentiation+++GO:0045786///negative regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0042542///response to hydrogen peroxide+++GO:0006915///apoptotic process+++GO:0051402///neuron apoptotic process+++GO:0042493///response to drug+++GO:0010165///response to X-ray+++GO:0043065///positive regulation of apoptotic process+++GO:0030218///erythrocyte differentiation","IPR002398///Peptidase C14 family+++IPR015471///Caspase-3/7+++IPR016129///Peptidase family C14A, His active site+++IPR015917///Peptidase C14A, caspase catalytic domain+++IPR029030///Caspase-like domain superfamily+++IPR002138///Peptidase C14, caspase non-catalytic subunit p10+++IPR033139///Peptidase family C14A, cysteine active site+++IPR001309///Peptidase C14,  p20 domain","[CASP3_HUMAN|Reviewed]RecName: Full=Caspase-3; Short=CASP-3; EC=3.4.22.56; AltName: Full=Apopain; AltName: Full=Cysteine protease CPP32; Short=CPP-32; AltName: Full=Protein Yama; AltName: Full=SREBP cleavage activity 1; Short=SCA-1; Contains: RecName: Full=Caspase-3 subunit p17; Contains: RecName: Full=Caspase-3 subunit p12; Flags: Precursor;+++[A8MVM1_HUMAN|Unreviewed]SubName: Full=Caspase-3 {ECO:0000313|Ensembl:ENSP00000377210};+++[C9JXR7_HUMAN|Unreviewed]SubName: Full=Caspase-3 {ECO:0000313|Ensembl:ENSP00000407142}; Flags: Fragment;"]
[83642,"'SELENOO'",456,416,436,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01880///Autosomal recessive microcephaly and chorioretinopathy",null,null,"GO:0005739///mitochondrion",null,null,"IPR003846///Uncharacterised protein family UPF0061","[SELO_HUMAN|Reviewed]RecName: Full=Selenoprotein O {ECO:0000303|PubMed:27645994}; Short=SelO {ECO:0000303|PubMed:12775843, ECO:0000303|PubMed:24751718, ECO:0000303|PubMed:27645994};+++[A0A087X0Q9_HUMAN|Unreviewed]SubName: Full=Selenoprotein O {ECO:0000313|Ensembl:ENSP00000483593};"]
[83695,"'RHNO1'",250,231,240.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0034644///cellular response to UV+++GO:0006974///cellular response to DNA damage stimulus+++GO:0070318///positive regulation of G0 to G1 transition+++GO:0007049///cell cycle+++GO:0071479///cellular response to ionizing radiation+++GO:0000725///recombinational repair+++GO:0000077///DNA damage checkpoint","IPR029293///Rad9, Rad1, Hus1-interacting nuclear orphan protein 1","[RHNO1_HUMAN|Reviewed]RecName: Full=RAD9, HUS1, RAD1-interacting nuclear orphan protein 1; AltName: Full=RAD9, RAD1, HUS1-interacting nuclear orphan protein;+++[F5H0U1_HUMAN|Unreviewed]SubName: Full=RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 {ECO:0000313|Ensembl:ENSP00000445936}; Flags: Fragment;+++[F5H580_HUMAN|Unreviewed]SubName: Full=RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 {ECO:0000313|Ensembl:ENSP00000444654}; Flags: Fragment;+++[F5H795_HUMAN|Unreviewed]SubName: Full=RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 {ECO:0000313|Ensembl:ENSP00000442677};+++[F5H7S2_HUMAN|Unreviewed]SubName: Full=RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 {ECO:0000313|Ensembl:ENSP00000442319}; Flags: Fragment;"]
[83729,"'INHBE'",0,3,1.5,"04550///Signaling pathways regulating pluripotency of stem cells+++04060///Cytokine-cytokine receptor interaction+++04350///TGF-beta signaling pathway",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0005179///hormone activity+++GO:0005125///cytokine activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0008083///growth factor activity","GO:0043408///regulation of MAPK cascade+++GO:0048468///cell development+++GO:0042981///regulation of apoptotic process+++GO:0060395///SMAD protein signal transduction+++GO:0010469///regulation of signaling receptor activity+++GO:0010862///positive regulation of pathway-restricted SMAD protein phosphorylation","IPR017948///Transforming growth factor beta, conserved site+++IPR001839///Transforming growth factor-beta, C-terminal+++IPR015615///Transforming growth factor-beta-related+++IPR001318///Inhibin, beta C subunit+++IPR029034///Cystine-knot cytokine","[INHBE_HUMAN|Reviewed]RecName: Full=Inhibin beta E chain; AltName: Full=Activin beta-E chain; Flags: Precursor;+++[F8VNP4_HUMAN|Unreviewed]SubName: Full=Inhibin beta E chain {ECO:0000313|Ensembl:ENSP00000450212}; Flags: Fragment;"]
[83787,"'ARMC10'",700.29,742.84,721.565,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0050692///DBD domain binding+++GO:0002039///p53 binding","GO:0043066///negative regulation of apoptotic process+++GO:0040008///regulation of growth+++GO:1902254///negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator+++GO:0040010///positive regulation of growth rate","IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical+++IPR006911///Armadillo repeat-containing domain","[ARM10_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing protein 10; AltName: Full=Splicing variant involved in hepatocarcinogenesis protein;+++[A0A0J9YWR7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000488082}; Flags: Fragment;+++[A0A0J9YXE4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000488365}; Flags: Fragment;+++[A0A0J9YXV5_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000488561}; Flags: Fragment;+++[A0A0J9YY38_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000488674}; Flags: Fragment;+++[C9J5N7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000398201}; Flags: Fragment;+++[H7BXM8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000305395};+++[H7BXQ8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000319798};+++[H7C2M7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing protein 10 {ECO:0000313|Ensembl:ENSP00000406840}; Flags: Fragment;"]
[83871,"'RAB34'",1374,1080,1227,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045335///phagocytic vesicle+++GO:0005795///Golgi stack+++GO:0005929///cilium+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005794///Golgi apparatus+++GO:0031410///cytoplasmic vesicle+++GO:0031985///Golgi cisterna+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0032587///ruffle membrane+++GO:0030670///phagocytic vesicle membrane+++GO:0031982///vesicle+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0042995///cell projection","GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0030742///GTP-dependent protein binding+++GO:0017160///Ral GTPase binding+++GO:0005515///protein binding","GO:0045880///positive regulation of smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0006886///intracellular protein transport+++GO:0019882///antigen processing and presentation+++GO:0015031///protein transport+++GO:0032418///lysosome localization+++GO:0043001///Golgi to plasma membrane protein transport+++GO:0044351///macropinocytosis+++GO:0090382///phagosome maturation+++GO:0072659///protein localization to plasma membrane+++GO:0032482///Rab protein signal transduction+++GO:0090385///phagosome-lysosome fusion","IPR001806///Small GTPase+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR005225///Small GTP-binding protein domain","[NARR_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-34, isoform NARR; AltName: Full=Nine amino-acid residue-repeats;+++[RAB34_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-34; AltName: Full=Ras-related protein Rab-39; AltName: Full=Ras-related protein Rah;+++[A0A024QZ68_HUMAN|Unreviewed]SubName: Full=RAB34, member RAS oncogene family, isoform CRA_b {ECO:0000313|EMBL:EAW51130.1};+++[A0A1B0GTQ2_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000489794};+++[A0A1B0GVI6_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000490529};+++[A0A1B0GWB1_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000490855};+++[A0A1C7CYW6_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000378664};+++[B4DNC0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61141, highly similar to Ras-related protein Rab-34 {ECO:0000313|EMBL:BAG60182.1};+++[C9JBG0_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000398706}; Flags: Fragment;+++[C9JY26_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000407953}; Flags: Fragment;+++[E7ES60_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000413156};+++[H7C0Y7_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000397499};+++[J3QLC6_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000463488}; Flags: Fragment;+++[K7EIF2_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000464723}; Flags: Fragment;+++[K7EJW7_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000465352}; Flags: Fragment;+++[Q6NXT3_HUMAN|Unreviewed]SubName: Full=RAB34 protein {ECO:0000313|EMBL:AAH66904.1};+++[Q96PJ7_HUMAN|Unreviewed]SubName: Full=Ras-related GTP-binding protein RAB39 {ECO:0000313|EMBL:AAL05587.1}; SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000487160};+++[V9GY61_HUMAN|Unreviewed]SubName: Full=Ras-related protein Rab-34, isoform NARR {ECO:0000313|Ensembl:ENSP00000476427}; Flags: Fragment;"]
[83892,"'KCTD10'",1520,1783,1651.5,"04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0005112///Notch binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0051260///protein homooligomerization","IPR011333///SKP1/BTB/POZ domain superfamily+++IPR003131///Potassium channel tetramerisation-type BTB domain+++IPR000210///BTB/POZ domain","[BACD3_HUMAN|Reviewed]RecName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000303|PubMed:19782033}; Short=hBACURD3 {ECO:0000303|PubMed:19782033}; AltName: Full=BTB/POZ domain-containing protein KCTD10; AltName: Full=Potassium channel tetramerization domain-containing protein 10;+++[A0A024RBJ2_HUMAN|Unreviewed]SubName: Full=Potassium channel tetramerisation domain containing 10, isoform CRA_b {ECO:0000313|EMBL:EAW97862.1};+++[B3KVY5_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000439722}; SubName: Full=Potassium channel tetramerisation domain containing 10, isoform CRA_a {ECO:0000313|EMBL:EAW97860.1}; SubName: Full=cDNA FLJ41739 fis, clone HSYRA2002590, highly similar to BTB/POZ domain-containing protein KCTD10 {ECO:0000313|EMBL:BAG53947.1};+++[F5GWA4_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000441672};+++[F5GWK6_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000441586}; Flags: Fragment;+++[F5GY15_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000440008}; Flags: Fragment;+++[F5H268_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000439481}; Flags: Fragment;+++[F5H497_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000445129}; Flags: Fragment;+++[F5H6V0_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000437348}; Flags: Fragment;+++[F8W8I7_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000390321};+++[L8E9A8_HUMAN|Unreviewed]SubName: Full=Alternative protein KCTD10 {ECO:0000313|EMBL:CCQ43754.1};+++[S4R3L9_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000474497};+++[S4R3Y7_HUMAN|Unreviewed]SubName: Full=BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 {ECO:0000313|Ensembl:ENSP00000474870};"]
[8395,"'PIP5K1B'",221,248,234.5,"04810///Regulation of actin cytoskeleton+++01100///Metabolic pathways+++04011///MAPK signaling pathway - yeast+++04139///Mitophagy - yeast+++05231///Choline metabolism in cancer+++04144///Endocytosis+++04666///Fc gamma R-mediated phagocytosis+++00562///Inositol phosphate metabolism+++04070///Phosphatidylinositol signaling system+++04072///Phospholipase D signaling pathway","H00865///Lethal congenital contractural syndrome (LCCS)","M00130///Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4","R03469///ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase   ATP + 1-Phosphatidyl-1D-myo-inositol 4-phosphate <=> ADP + 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate","GO:0001931///uropod+++GO:0005829///cytosol+++GO:0012505///endomembrane system+++GO:0016020///membrane","GO:0016308///1-phosphatidylinositol-4-phosphate 5-kinase activity+++GO:0005515///protein binding+++GO:0052811///1-phosphatidylinositol-3-phosphate 4-kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0052810///1-phosphatidylinositol-5-kinase activity+++GO:0016301///kinase activity+++GO:0016307///phosphatidylinositol phosphate kinase activity+++GO:0000285///1-phosphatidylinositol-3-phosphate 5-kinase activity+++GO:0052812///phosphatidylinositol-3,4-bisphosphate 5-kinase activity+++GO:0016740///transferase activity","GO:0006661///phosphatidylinositol biosynthetic process+++GO:0046488///phosphatidylinositol metabolic process+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0014066///regulation of phosphatidylinositol 3-kinase signaling+++GO:0016310///phosphorylation","IPR027484///Phosphatidylinositol-4-phosphate 5-kinase, N-terminal+++IPR002498///Phosphatidylinositol-4-phosphate 5-kinase, core+++IPR023610///Phosphatidylinositol-4-phosphate 5-kinase+++IPR027483///Phosphatidylinositol-4-phosphate 5-kinase, C-terminal","[PI51B_HUMAN|Reviewed]RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 beta; Short=PIP5K1-beta; Short=PtdIns(4)P-5-kinase 1 beta; EC=2.7.1.68; AltName: Full=Phosphatidylinositol 4-phosphate 5-kinase type I beta; Short=PIP5KIbeta; AltName: Full=Protein STM-7; AltName: Full=Type I phosphatidylinositol 4-phosphate 5-kinase beta;+++[A0A0A0MRU3_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 beta {ECO:0000313|Ensembl:ENSP00000366498}; Flags: Fragment;+++[A0A0A0MSP5_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 beta {ECO:0000313|Ensembl:ENSP00000398587}; Flags: Fragment;+++[A0A0A0MT25_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate 5-kinase type-1 beta {ECO:0000313|Ensembl:ENSP00000411477}; Flags: Fragment;+++[Q7KYT4_HUMAN|Unreviewed]SubName: Full=Type I phosphatidylinositol-4-phosphate 5-kinase beta {ECO:0000313|EMBL:AAC50916.1}; EC=2.7.1.68 {ECO:0000313|EMBL:AAC50916.1}; Flags: Fragment;+++[Q7KYT6_HUMAN|Unreviewed]SubName: Full=Type I phosphatidylinositol-4-phosphate 5-kinase beta {ECO:0000313|EMBL:AAC50914.1}; EC=2.7.1.68 {ECO:0000313|EMBL:AAC50914.1}; Flags: Fragment;"]
[84000,"'TMPRSS13'",1,0,0.5,"05164///Influenza A",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0072562///blood microparticle+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0004252///serine-type endopeptidase activity+++GO:0008236///serine-type peptidase activity+++GO:0005044///scavenger receptor activity+++GO:0008233///peptidase activity","GO:0006898///receptor-mediated endocytosis+++GO:0006508///proteolysis","IPR009003///Peptidase S1, PA clan+++IPR001190///SRCR domain+++IPR001314///Peptidase S1A, chymotrypsin family+++IPR017448///SRCR-like domain+++IPR001254///Serine proteases, trypsin domain+++IPR036772///SRCR-like domain superfamily+++IPR018114///Serine proteases, trypsin family, histidine active site+++IPR017327///Peptidase S1A, TMPRSS13+++IPR033116///Serine proteases, trypsin family, serine active site+++IPR002172///Low-density lipoprotein (LDL) receptor class A repeat","[TMPSD_HUMAN|Reviewed]RecName: Full=Transmembrane protease serine 13; EC=3.4.21.-; AltName: Full=Membrane-type mosaic serine protease; Short=Mosaic serine protease;+++[E9PR79_HUMAN|Unreviewed]SubName: Full=Transmembrane protease serine 13 {ECO:0000313|Ensembl:ENSP00000436025};+++[E9PRA0_HUMAN|Unreviewed]SubName: Full=Transmembrane protease serine 13 {ECO:0000313|Ensembl:ENSP00000434279};+++[J3KQC6_HUMAN|Unreviewed]SubName: Full=Transmembrane protease serine 13 {ECO:0000313|Ensembl:ENSP00000394114};+++[Q1RMF8_HUMAN|Unreviewed]SubName: Full=TMPRSS13 protein {ECO:0000313|EMBL:AAI14929.1};"]
[84063,"'KIRREL2'",29,13,21,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005911///cell-cell junction+++GO:0005886///plasma membrane+++GO:0036057///slit diaphragm+++GO:0016020///membrane","GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0001933///negative regulation of protein phosphorylation","IPR003599///Immunoglobulin subtype+++IPR007110///Immunoglobulin-like domain+++IPR013162///CD80-like, immunoglobulin C2-set+++IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013098///Immunoglobulin I-set+++IPR003598///Immunoglobulin subtype 2","[KIRR2_HUMAN|Reviewed]RecName: Full=Kin of IRRE-like protein 2; AltName: Full=Kin of irregular chiasm-like protein 2; AltName: Full=Nephrin-like protein 3; Flags: Precursor;+++[A0A0A0MQV3_HUMAN|Unreviewed]SubName: Full=Kin of IRRE-like protein 2 {ECO:0000313|Ensembl:ENSP00000262625};+++[A0A0A0MRC1_HUMAN|Unreviewed]SubName: Full=Kin of IRRE-like protein 2 {ECO:0000313|Ensembl:ENSP00000345067};+++[K7EJS8_HUMAN|Unreviewed]SubName: Full=Kin of IRRE-like protein 2 {ECO:0000313|Ensembl:ENSP00000465305};+++[V9GXZ7_HUMAN|Unreviewed]SubName: Full=Kin of IRRE-like protein 2 {ECO:0000313|Ensembl:ENSP00000466460}; Flags: Fragment;"]
[84080,"'ENKD1'",164,157,160.5,{"$nulls":4},"GO:0015630///microtubule cytoskeleton+++GO:0005881///cytoplasmic microtubule","GO:0005515///protein binding",null,"IPR027710///Enkurin domain-containing protein 1+++IPR027012///Enkurin domain","[ENKD1_HUMAN|Reviewed]RecName: Full=Enkurin domain-containing protein 1;+++[A0A087X0D0_HUMAN|Unreviewed]SubName: Full=Enkurin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000483290}; Flags: Fragment;+++[R4GN60_HUMAN|Unreviewed]SubName: Full=Enkurin domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000473501};"]
[8412,"'BCAR3'",1541,1575,1558,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005938///cell cortex+++GO:0005856///cytoskeleton+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0005634///nucleus","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0033138///positive regulation of peptidyl-serine phosphorylation+++GO:0042493///response to drug+++GO:0002089///lens morphogenesis in camera-type eye+++GO:0007264///small GTPase mediated signal transduction","IPR036964///Ras guanine-nucleotide exchange factor catalytic domain superfamily+++IPR023578///Ras guanine nucleotide exchange factor domain superfamily+++IPR036860///SH2 domain superfamily+++IPR028849///Breast cancer anti-estrogen resistance protein 3+++IPR001895///Ras guanine-nucleotide exchange factors catalytic domain+++IPR000980///SH2 domain","[BCAR3_HUMAN|Reviewed]RecName: Full=Breast cancer anti-estrogen resistance protein 3; AltName: Full=Novel SH2-containing protein 2; AltName: Full=SH2 domain-containing protein 3B;+++[B3KNL6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14879 fis, clone PLACE1003353, highly similar to Breast cancer anti-estrogen resistance protein 3 {ECO:0000313|EMBL:BAG51378.1};+++[B3KP06_HUMAN|Unreviewed]SubName: Full=cDNA FLJ30880 fis, clone FEBRA2004767, highly similar to Breast cancer anti-estrogen resistance protein 3 {ECO:0000313|EMBL:BAG51518.1};"]
[84144,"'SYDE2'",31,33,32,{"$nulls":4},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0090630///activation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007165///signal transduction","IPR035892///C2 domain superfamily+++IPR000198///Rho GTPase-activating protein domain+++IPR008936///Rho GTPase activation protein","[SYDE2_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein SYDE2; AltName: Full=Synapse defective protein 1 homolog 2; Short=Protein syd-1 homolog 2;+++[A0A2X0SFY5_HUMAN|Unreviewed]SubName: Full=SYDE2 {ECO:0000313|EMBL:SPT35804.1}; Flags: Fragment;"]
[84172,"'POLR1B'",196,182,189,"01100///Metabolic pathways+++03020///RNA polymerase+++00230///Purine metabolism+++00240///Pyrimidine metabolism",null,"M00182///RNA polymerase I, eukaryotes","R00443///UTP:RNA uridylyltransferase   UTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA   ATP + RNA <=> Diphosphate + RNA+++R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA   GTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA   CTP + RNA <=> Diphosphate + RNA","GO:0035861///site of double-strand break+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000785///chromatin+++GO:0000781///chromosome, telomeric region+++GO:0016604///nuclear body+++GO:0005736///RNA polymerase I complex+++GO:0005730///nucleolus+++GO:0005662///DNA replication factor A complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0016605///PML body","GO:0032549///ribonucleoside binding+++GO:0019903///protein phosphatase binding+++GO:0016779///nucleotidyltransferase activity+++GO:0019899///enzyme binding+++GO:0016740///transferase activity+++GO:0098505///G-rich strand telomeric DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0001054///RNA polymerase I activity+++GO:0003697///single-stranded DNA binding+++GO:0047485///protein N-terminus binding+++GO:0003684///damaged DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0043565///sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003690///double-stranded DNA binding+++GO:0031625///ubiquitin protein ligase binding","GO:0033683///nucleotide-excision repair, DNA incision+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0006260///DNA replication+++GO:0045815///positive regulation of gene expression, epigenetic+++GO:0036297///interstrand cross-link repair+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0017126///nucleologenesis+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0009303///rRNA transcription+++GO:0032201///telomere maintenance via semi-conservative replication+++GO:0006297///nucleotide-excision repair, DNA gap filling+++GO:0019985///translesion synthesis+++GO:0000722///telomere maintenance via recombination+++GO:0007004///telomere maintenance via telomerase+++GO:0070987///error-free translesion synthesis+++GO:0006281///DNA repair+++GO:0010569///regulation of double-strand break repair via homologous recombination+++GO:0006974///cellular response to DNA damage stimulus+++GO:0031571///mitotic G1 DNA damage checkpoint+++GO:0006351///transcription, DNA-templated+++GO:0030491///heteroduplex formation+++GO:0006289///nucleotide-excision repair+++GO:0042276///error-prone translesion synthesis+++GO:2000001///regulation of DNA damage checkpoint+++GO:0051096///positive regulation of helicase activity+++GO:0006361///transcription initiation from RNA polymerase I promoter+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0006312///mitotic recombination+++GO:0006363///termination of RNA polymerase I transcription+++GO:0006298///mismatch repair+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006268///DNA unwinding involved in DNA replication+++GO:1900034///regulation of cellular response to heat+++GO:0006284///base-excision repair+++GO:0006310///DNA recombination+++GO:0006265///DNA topological change+++GO:0034502///protein localization to chromosome+++GO:0000723///telomere maintenance+++GO:0007566///embryo implantation","IPR037034///RNA polymerase Rpb2, domain 2 superfamily+++IPR007644///RNA polymerase, beta subunit, protrusion+++IPR037033///DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily+++IPR007121///RNA polymerase, beta subunit, conserved site+++IPR009674///DNA-directed RNA polymerase I subunit RPA2, domain 4+++IPR007642///RNA polymerase Rpb2, domain 2+++IPR015712///DNA-directed RNA polymerase, subunit 2+++IPR007641///RNA polymerase Rpb2, domain 7+++IPR007645///RNA polymerase Rpb2, domain 3+++IPR014724///RNA polymerase Rpb2, OB-fold+++IPR007120///DNA-directed RNA polymerase, subunit 2, hybrid-binding domain","[RPA2_HUMAN|Reviewed]RecName: Full=DNA-directed RNA polymerase I subunit RPA2; Short=RNA polymerase I subunit 2; EC=2.7.7.6; AltName: Full=DNA-directed RNA polymerase I 135 kDa polypeptide; Short=RPA135;+++[B7Z1W6_HUMAN|Unreviewed]RecName: Full=DNA-directed RNA polymerase subunit beta {ECO:0000256|RuleBase:RU363031}; EC=2.7.7.6 {ECO:0000256|RuleBase:RU363031};+++[C9JJG2_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000415754}; Flags: Fragment;+++[C9JS83_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000388577}; Flags: Fragment;+++[F8WAK7_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000334589};+++[F8WBB9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000390973};+++[F8WCS3_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000390274};+++[F8WDS4_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000403094};+++[H7C0D9_HUMAN|Unreviewed]SubName: Full=DNA-directed RNA polymerase I subunit RPA2 {ECO:0000313|Ensembl:ENSP00000394408}; Flags: Fragment;+++[Q4QRK8_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH96748.1}; Flags: Fragment;+++[Q5TEJ0_HUMAN|Unreviewed]SubName: Full=Replication protein A 32 kDa subunit {ECO:0000313|Ensembl:ENSP00000413541}; Flags: Fragment;+++[Q5TEJ7_HUMAN|Unreviewed]SubName: Full=Replication protein A 32 kDa subunit {ECO:0000313|Ensembl:ENSP00000387649}; Flags: Fragment;+++[Q6DKI9_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH73857.1}; Flags: Fragment;+++[Q9BSR4_HUMAN|Unreviewed]SubName: Full=POLR1B protein {ECO:0000313|EMBL:AAH04882.4}; Flags: Fragment;"]
[84206,"'MEX3B'",318,344,331,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0000932///P-body+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005509///calcium ion binding+++GO:0003723///RNA binding","GO:0006468///protein phosphorylation+++GO:0046777///protein autophosphorylation","IPR004087///K Homology domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR036612///K Homology domain, type 1 superfamily+++IPR001841///Zinc finger, RING-type+++IPR004088///K Homology domain, type 1","[MEX3B_HUMAN|Reviewed]RecName: Full=RNA-binding protein MEX3B; AltName: Full=RING finger and KH domain-containing protein 3; AltName: Full=RING finger protein 195;"]
[84233,"'TMEM126A'",91,88,89.5,null,"H01020///Optic atrophy (OPA)",null,null,"GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0016021///integral component of membrane","GO:0003674///molecular_function","GO:0021554///optic nerve development","IPR009801///Transmembrane protein 126","[T126A_HUMAN|Reviewed]RecName: Full=Transmembrane protein 126A;+++[E9PI90_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 126A {ECO:0000313|Ensembl:ENSP00000436723};+++[E9PIH8_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 126A {ECO:0000313|Ensembl:ENSP00000431993};"]
[84255,"'SLC37A3'",243,282,262.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0005789///endoplasmic reticulum membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016020///membrane","GO:0061513///glucose 6-phosphate:inorganic phosphate antiporter activity+++GO:0022857///transmembrane transporter activity","GO:0015712///hexose phosphate transport+++GO:0035435///phosphate ion transmembrane transport+++GO:0055085///transmembrane transport+++GO:0015760///glucose-6-phosphate transport+++GO:0008643///carbohydrate transport","IPR036259///MFS transporter superfamily+++IPR000849///Sugar phosphate transporter+++IPR011701///Major facilitator superfamily+++IPR020846///Major facilitator superfamily domain","[SPX3_HUMAN|Reviewed]RecName: Full=Sugar phosphate exchanger 3; AltName: Full=Solute carrier family 37 member 3;+++[C9J4S7_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000417181}; Flags: Fragment;+++[C9JZ37_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000419024}; Flags: Fragment;+++[F8WAR9_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000417365};+++[F8WC97_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000418585};+++[F8WF28_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000419410};+++[H7C4I4_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000417380}; Flags: Fragment;+++[H7C4J2_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000417447}; Flags: Fragment;+++[H7C4J3_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000417449}; Flags: Fragment;+++[H7C4J5_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000417461}; Flags: Fragment;+++[H7C4U0_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000418136}; Flags: Fragment;+++[H7C4U5_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000418158}; Flags: Fragment;+++[H7C4Z5_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000418610}; Flags: Fragment;+++[H7C594_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000419285}; Flags: Fragment;+++[H7C5E7_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000419701}; Flags: Fragment;+++[H7C5T4_HUMAN|Unreviewed]SubName: Full=Sugar phosphate exchanger 3 {ECO:0000313|Ensembl:ENSP00000420771}; Flags: Fragment;"]
[84270,"'CARD19'",289,208,248.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0031966///mitochondrial membrane+++GO:0005829///cytosol+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005634///nucleus","GO:0050700///CARD domain binding","GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling","IPR001315///CARD domain+++IPR011029///Death-like domain superfamily","[CAR19_HUMAN|Reviewed]RecName: Full=Caspase recruitment domain-containing protein 19; AltName: Full=Bcl10-interacting CARD protein; Short=BinCARD;+++[A0A024R248_HUMAN|Unreviewed]SubName: Full=Chromosome 9 open reading frame 89, isoform CRA_b {ECO:0000313|EMBL:EAW62852.1};"]
[84285,"'EIF1AD'",429,380,404.5,"03040///Spliceosome",null,"M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003743///translation initiation factor activity","GO:0006412///translation+++GO:0006413///translational initiation","IPR001253///Translation initiation factor 1A (eIF-1A)+++IPR039294///Probable RNA-binding protein EIF1AD+++IPR006196///RNA-binding domain, S1, IF1 type+++IPR012340///Nucleic acid-binding, OB-fold","[EIF1A_HUMAN|Reviewed]RecName: Full=Probable RNA-binding protein EIF1AD; AltName: Full=Eukaryotic translation initiation factor 1A domain-containing protein; AltName: Full=Haponin;+++[A0A024R5B9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW74480.1};+++[E9PLI6_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein EIF1AD {ECO:0000313|Ensembl:ENSP00000433320}; Flags: Fragment;+++[E9PNH5_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein EIF1AD {ECO:0000313|Ensembl:ENSP00000434796};+++[E9PQD0_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein EIF1AD {ECO:0000313|Ensembl:ENSP00000436876};+++[E9PS30_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein EIF1AD {ECO:0000313|Ensembl:ENSP00000432135}; Flags: Fragment;+++[E9PS76_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein EIF1AD {ECO:0000313|Ensembl:ENSP00000435891}; Flags: Fragment;"]
[84301,"'DDI2'",17.74,34,25.87,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0008233///peptidase activity+++GO:0043130///ubiquitin binding+++GO:0005515///protein binding+++GO:0004190///aspartic-type endopeptidase activity+++GO:0042802///identical protein binding","GO:0016485///protein processing+++GO:0006508///proteolysis","IPR033322///DNA damage-inducible protein 1+++IPR000626///Ubiquitin domain+++IPR033882///DNA damage inducible protein 1 ubiquitin-like domain+++IPR029071///Ubiquitin-like domain superfamily+++IPR019103///Aspartic peptidase, DDI1-type+++IPR021109///Aspartic peptidase domain superfamily","[DDI2_HUMAN|Reviewed]RecName: Full=Protein DDI1 homolog 2 {ECO:0000305}; EC=3.4.23.- {ECO:0000269|PubMed:27528193};+++[H0YI90_HUMAN|Unreviewed]SubName: Full=Protein DDI1 homolog 2 {ECO:0000313|Ensembl:ENSP00000448878}; Flags: Fragment;+++[H0YII4_HUMAN|Unreviewed]SubName: Full=Protein DDI1 homolog 2 {ECO:0000313|Ensembl:ENSP00000449475}; Flags: Fragment;"]
[84317,"'CCDC115'",186,112,149,{"$nulls":4},"GO:0005764///lysosome+++GO:0031410///cytoplasmic vesicle+++GO:0005768///endosome+++GO:0042406///extrinsic component of endoplasmic reticulum membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0016020///membrane+++GO:0016471///vacuolar proton-transporting V-type ATPase complex+++GO:0005783///endoplasmic reticulum+++GO:0030137///COPI-coated vesicle","GO:0051082///unfolded protein binding","GO:0036295///cellular response to increased oxygen levels+++GO:0007042///lysosomal lumen acidification+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0006879///cellular iron ion homeostasis+++GO:1905146///lysosomal protein catabolic process",null,"[CC115_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 115 {ECO:0000303|PubMed:26833332};+++[A0A024QZZ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW55612.1};+++[B8ZZ99_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 115 {ECO:0000313|Ensembl:ENSP00000387301};+++[F8WCZ3_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 115 {ECO:0000313|Ensembl:ENSP00000403480};"]
[84335,"'AKT1S1'",5904,5614,5759,"04714///Thermogenesis+++04140///Autophagy - animal+++04211///Longevity regulating pathway+++04152///AMPK signaling pathway+++04213///Longevity regulating pathway - multiple species+++04150///mTOR signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0031931///TORC1 complex+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0038202///TORC1 signaling+++GO:0043523///regulation of neuron apoptotic process+++GO:0032007///negative regulation of TOR signaling+++GO:0048011///neurotrophin TRK receptor signaling pathway+++GO:0006469///negative regulation of protein kinase activity+++GO:0042981///regulation of apoptotic process+++GO:1900034///regulation of cellular response to heat+++GO:0045792///negative regulation of cell size","IPR026682///Proline-rich AKT1 substrate 1 protein","[AKTS1_HUMAN|Reviewed]RecName: Full=Proline-rich AKT1 substrate 1; AltName: Full=40 kDa proline-rich AKT substrate;+++[A0A024QZF6_HUMAN|Unreviewed]SubName: Full=AKT1 substrate 1 (Proline-rich), isoform CRA_a {ECO:0000313|EMBL:EAW52571.1};+++[H9KV91_HUMAN|Unreviewed]SubName: Full=Proline-rich AKT1 substrate 1 {ECO:0000313|Ensembl:ENSP00000375706}; Flags: Fragment;+++[M0R2V8_HUMAN|Unreviewed]SubName: Full=Proline-rich AKT1 substrate 1 {ECO:0000313|Ensembl:ENSP00000472839}; Flags: Fragment;"]
[8440,"'NCK2'",572,518,545,"04012///ErbB signaling pathway+++05130///Pathogenic Escherichia coli infection+++04660///T cell receptor signaling pathway+++04360///Axon guidance",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum+++GO:0045202///synapse+++GO:0012506///vesicle membrane+++GO:0005829///cytosol+++GO:0014069///postsynaptic density","GO:0097110///scaffold protein binding+++GO:0008093///cytoskeletal adaptor activity+++GO:0044877///protein-containing complex binding+++GO:0030159///receptor signaling complex scaffold activity+++GO:0001784///phosphotyrosine residue binding+++GO:0005515///protein binding+++GO:0005070///SH3/SH2 adaptor activity","GO:0042110///T cell activation+++GO:1903898///negative regulation of PERK-mediated unfolded protein response+++GO:0048013///ephrin receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007172///signal complex assembly+++GO:0042102///positive regulation of T cell proliferation+++GO:1902237///positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0007015///actin filament organization+++GO:0030032///lamellipodium assembly+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:1990441///negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress+++GO:0008285///negative regulation of cell proliferation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007173///epidermal growth factor receptor signaling pathway+++GO:0007176///regulation of epidermal growth factor-activated receptor activity+++GO:0060996///dendritic spine development+++GO:0030838///positive regulation of actin filament polymerization+++GO:0009967///positive regulation of signal transduction+++GO:0016477///cell migration+++GO:1903912///negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation+++GO:0006417///regulation of translation+++GO:0036493///positive regulation of translation in response to endoplasmic reticulum stress+++GO:0001771///immunological synapse formation","IPR036028///SH3-like domain superfamily+++IPR035560///Nck2, SH3 domain 2+++IPR017304///Cytoplasmic protein NCK+++IPR035883///Nck2, SH2 domain+++IPR035561///Nck2, SH3 domain 3+++IPR001452///SH3 domain+++IPR035559///Nck2, SH3 domain 1+++IPR000980///SH2 domain+++IPR036860///SH2 domain superfamily","[NCK2_HUMAN|Reviewed]RecName: Full=Cytoplasmic protein NCK2; AltName: Full=Growth factor receptor-bound protein 4; AltName: Full=NCK adaptor protein 2; Short=Nck-2; AltName: Full=SH2/SH3 adaptor protein NCK-beta;+++[A0A0S2Z4M6_HUMAN|Unreviewed]SubName: Full=NCK adaptor protein 2 isoform 1 {ECO:0000313|EMBL:ALQ33876.1}; Flags: Fragment;+++[E7EPF5_HUMAN|Unreviewed]SubName: Full=Cytoplasmic protein NCK2 {ECO:0000313|Ensembl:ENSP00000377017}; Flags: Fragment;+++[E7ERP6_HUMAN|Unreviewed]SubName: Full=Cytoplasmic protein NCK2 {ECO:0000313|Ensembl:ENSP00000410428}; SubName: Full=NCK adaptor protein 2 isoform 2 {ECO:0000313|EMBL:ALQ33877.1};+++[E9PEE2_HUMAN|Unreviewed]SubName: Full=Cytoplasmic protein NCK2 {ECO:0000313|Ensembl:ENSP00000408040}; Flags: Fragment;+++[Q53T91_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein NCK2 {ECO:0000313|EMBL:AAY14937.1}; Flags: Fragment;+++[Q53TG4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein NCK2 {ECO:0000313|EMBL:AAY24332.1}; Flags: Fragment;"]
[84446,"'BRSK1'",406,385,395.5,{"$nulls":4},"GO:0005813///centrosome+++GO:0150034///distal axon+++GO:0005654///nucleoplasm+++GO:0045202///synapse+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0048786///presynaptic active zone+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction+++GO:0005856///cytoskeleton","GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0000287///magnesium ion binding+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0050321///tau-protein kinase activity+++GO:0043015///gamma-tubulin binding+++GO:0048156///tau protein binding","GO:0010975///regulation of neuron projection development+++GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0048812///neuron projection morphogenesis+++GO:0009411///response to UV+++GO:0016310///phosphorylation+++GO:0099504///synaptic vesicle cycle+++GO:0007049///cell cycle+++GO:0035556///intracellular signal transduction+++GO:0007409///axonogenesis+++GO:0050770///regulation of axonogenesis+++GO:0007399///nervous system development+++GO:0030182///neuron differentiation+++GO:0048167///regulation of synaptic plasticity+++GO:0051298///centrosome duplication+++GO:0007095///mitotic G2 DNA damage checkpoint+++GO:0007269///neurotransmitter secretion+++GO:0010212///response to ionizing radiation+++GO:0030010///establishment of cell polarity+++GO:0008306///associative learning+++GO:2000807///regulation of synaptic vesicle clustering+++GO:0090176///microtubule cytoskeleton organization involved in establishment of planar polarity","IPR015940///Ubiquitin-associated domain+++IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site+++IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site","[BRSK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase BRSK1; EC=2.7.11.1; AltName: Full=Brain-selective kinase 1; EC=2.7.11.26; AltName: Full=Brain-specific serine/threonine-protein kinase 1; Short=BR serine/threonine-protein kinase 1; AltName: Full=Serine/threonine-protein kinase SAD-B; AltName: Full=Synapses of Amphids Defective homolog 1; Short=SAD1 homolog; Short=hSAD1;+++[J3KNK0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase BRSK1 {ECO:0000313|Ensembl:ENSP00000320853};+++[K7EM68_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase BRSK1 {ECO:0000313|Ensembl:ENSP00000466380}; Flags: Fragment;+++[K7EN26_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase BRSK1 {ECO:0000313|Ensembl:ENSP00000466755}; Flags: Fragment;"]
[84466,"'MEGF10'",7,9,8,{"$nulls":4},"GO:0042995///cell projection+++GO:0016020///membrane+++GO:0001891///phagocytic cup+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane","GO:0005112///Notch binding+++GO:0005044///scavenger receptor activity+++GO:0001849///complement component C1q binding","GO:0051451///myoblast migration+++GO:0048641///regulation of skeletal muscle tissue development+++GO:0014841///skeletal muscle satellite cell proliferation+++GO:0014719///skeletal muscle satellite cell activation+++GO:1902742///apoptotic process involved in development+++GO:0043654///recognition of apoptotic cell+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0034109///homotypic cell-cell adhesion+++GO:0051147///regulation of muscle cell differentiation+++GO:0007517///muscle organ development+++GO:0033002///muscle cell proliferation+++GO:0006909///phagocytosis+++GO:0007155///cell adhesion+++GO:0055001///muscle cell development+++GO:0006898///receptor-mediated endocytosis+++GO:0043652///engulfment of apoptotic cell","IPR002049///Laminin EGF domain+++IPR013032///EGF-like, conserved site+++IPR011489///EMI domain+++IPR000742///EGF-like domain","[MEG10_HUMAN|Reviewed]RecName: Full=Multiple epidermal growth factor-like domains protein 10 {ECO:0000312|HGNC:HGNC:29634}; Short=Multiple EGF-like domains protein 10 {ECO:0000305}; Flags: Precursor;"]
[84516,"'DCTN5'",1240.26,1544.09,1392.175,"04962///Vasopressin-regulated water reabsorption",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0000777///condensed chromosome kinetochore+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0000776///kinetochore+++GO:0031965///nuclear membrane+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005515///protein binding","GO:0003281///ventricular septum development+++GO:0060976///coronary vasculature development+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0035904///aorta development+++GO:0006888///ER to Golgi vesicle-mediated transport","IPR011004///Trimeric LpxA-like superfamily+++IPR001451///Hexapeptide repeat","[DCTN5_HUMAN|Reviewed]RecName: Full=Dynactin subunit 5; AltName: Full=Dynactin subunit p25;+++[H3BR94_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 5 {ECO:0000313|Ensembl:ENSP00000456137};+++[H3BS05_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 5 {ECO:0000313|Ensembl:ENSP00000456483};+++[H3BUD2_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 5 {ECO:0000313|Ensembl:ENSP00000457585};+++[I3L0U8_HUMAN|Unreviewed]SubName: Full=Dynactin subunit 5 {ECO:0000313|Ensembl:ENSP00000458354}; Flags: Fragment;"]
[84542,"'KIAA1841'",32,51,41.5,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04146///Peroxisome","H01342///Zellweger syndrome (ZS)+++H00177///Adrenoleukodystrophy, neonatal (NALD)+++H00205///Peroxisome biogenesis disorder",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding","GO:0010468///regulation of gene expression","IPR001005///SANT/Myb domain+++IPR021777///Domain of unknown function DUF3342","[K1841_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA1841;+++[F8VWD7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA1841 {ECO:0000313|Ensembl:ENSP00000413200};"]
[8460,"'TPST1'",272,266,269,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030173///integral component of Golgi membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane","GO:0008476///protein-tyrosine sulfotransferase activity+++GO:0016740///transferase activity+++GO:0042803///protein homodimerization activity","GO:0006478///peptidyl-tyrosine sulfation+++GO:0006954///inflammatory response+++GO:0050427///3'-phosphoadenosine 5'-phosphosulfate metabolic process","IPR026634///Protein-tyrosine sulfotransferase+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[TPST1_HUMAN|Reviewed]RecName: Full=Protein-tyrosine sulfotransferase 1; EC=2.8.2.20 {ECO:0000269|PubMed:28821720, ECO:0000269|PubMed:9501187, ECO:0000269|PubMed:9733778}; AltName: Full=Tyrosylprotein sulfotransferase 1; Short=TPST-1;+++[A0A024RDK9_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018};+++[C9J3I4_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018}; Flags: Fragment;+++[C9K0F3_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018}; Flags: Fragment;+++[Q75M96_HUMAN|Unreviewed]RecName: Full=Protein-tyrosine sulfotransferase {ECO:0000256|RuleBase:RU365018}; EC=2.8.2.20 {ECO:0000256|RuleBase:RU365018}; Flags: Fragment;+++[Q75ML6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TPST1 {ECO:0000313|EMBL:AAS02012.1}; Flags: Fragment;"]
[84630,"'TTBK1'",31,47,39,null,"H00063///Spinocerebellar ataxia (SCA)",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005875///microtubule associated complex+++GO:0043025///neuronal cell body+++GO:0005654///nucleoplasm","GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0004672///protein kinase activity+++GO:0048156///tau protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0050321///tau-protein kinase activity+++GO:0005524///ATP binding+++GO:0016301///kinase activity","GO:0010629///negative regulation of gene expression+++GO:0021762///substantia nigra development+++GO:0061890///positive regulation of astrocyte activation+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0032273///positive regulation of protein polymerization+++GO:0018105///peptidyl-serine phosphorylation+++GO:1903980///positive regulation of microglial cell activation+++GO:0007611///learning or memory+++GO:0016310///phosphorylation+++GO:0010628///positive regulation of gene expression+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:1904031///positive regulation of cyclin-dependent protein kinase activity+++GO:0032091///negative regulation of protein binding+++GO:2001056///positive regulation of cysteine-type endopeptidase activity+++GO:0006468///protein phosphorylation","IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site","[TTBK1_HUMAN|Reviewed]RecName: Full=Tau-tubulin kinase 1; EC=2.7.11.1 {ECO:0000269|PubMed:16923168}; AltName: Full=Brain-derived tau kinase;+++[L8E9F5_HUMAN|Unreviewed]SubName: Full=Alternative protein TTBK1 {ECO:0000313|EMBL:CCQ43769.1};+++[X6R456_HUMAN|Unreviewed]SubName: Full=Tau-tubulin kinase 1 {ECO:0000313|Ensembl:ENSP00000307357};"]
[84669,"'USP32'",499.11,675.5,587.305,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0032991///protein-containing complex+++GO:0005654///nucleoplasm+++GO:0005769///early endosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005768///endosome","GO:0005509///calcium ion binding+++GO:0008233///peptidase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0002039///p53 binding+++GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0044325///ion channel binding+++GO:0003723///RNA binding","GO:0006914///autophagy+++GO:0071347///cellular response to interleukin-1+++GO:0019985///translesion synthesis+++GO:0043124///negative regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016579///protein deubiquitination+++GO:0030330///DNA damage response, signal transduction by p53 class mediator+++GO:0006508///proteolysis+++GO:0010506///regulation of autophagy+++GO:0006281///DNA repair","IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase+++IPR002048///EF-hand domain+++IPR018247///EF-Hand 1, calcium-binding site+++IPR011992///EF-hand domain pair+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR028889///Ubiquitin specific protease domain+++IPR018200///Ubiquitin specific protease, conserved site+++IPR028135///Ubiquitin-like domain, USP-type+++IPR035927///DUSP-like superfamily+++IPR006615///Peptidase C19, ubiquitin-specific peptidase, DUSP domain","[UBP32_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 32; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 32; AltName: Full=Renal carcinoma antigen NY-REN-60; AltName: Full=Ubiquitin thioesterase 32; AltName: Full=Ubiquitin-specific-processing protease 32; Flags: Precursor;+++[H3BNA1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454751}; Flags: Fragment;+++[H3BNL0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454902};+++[H3BNP1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454943};+++[H3BNS8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000454987}; Flags: Fragment;+++[H3BQC6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000455712}; Flags: Fragment;+++[H3BQP1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000455865}; Flags: Fragment;+++[H3BVF1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000458089}; Flags: Fragment;+++[J3KT19_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000462762}; Flags: Fragment;+++[K7EII4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000464762}; Flags: Fragment;+++[K7EKK3_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000465659}; Flags: Fragment;+++[K7EKZ1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000465844}; Flags: Fragment;+++[K7EL53_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000465922}; Flags: Fragment;+++[K7EN13_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000466740}; Flags: Fragment;+++[K7ENU6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000467098}; Flags: Fragment;+++[K7EPL4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000467435}; Flags: Fragment;+++[K7EQL6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 32 {ECO:0000313|Ensembl:ENSP00000467885};+++[Q4VC15_HUMAN|Unreviewed]SubName: Full=USP32 protein {ECO:0000313|EMBL:AAH94680.1}; Flags: Fragment;+++[Q68D90_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 10 {ECO:0000313|Ensembl:ENSP00000445589};+++[Q6IRT0_HUMAN|Unreviewed]SubName: Full=USP32 protein {ECO:0000313|EMBL:AAH70497.1}; Flags: Fragment;+++[Q6P2I0_HUMAN|Unreviewed]SubName: Full=USP10 protein {ECO:0000313|EMBL:AAH64516.1}; Flags: Fragment;"]
[84696,"'ABHD1'",0,6,3,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04141///Protein processing in endoplasmic reticulum",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0016787///hydrolase activity+++GO:0003674///molecular_function+++GO:0005515///protein binding+++GO:0047372///acylglycerol lipase activity+++GO:0034338///short-chain carboxylesterase activity+++GO:0016298///lipase activity+++GO:0052689///carboxylic ester hydrolase activity","GO:0044255///cellular lipid metabolic process+++GO:0051792///medium-chain fatty acid biosynthetic process+++GO:0008150///biological_process+++GO:0051793///medium-chain fatty acid catabolic process","IPR029058///Alpha/Beta hydrolase fold+++IPR012020///AB hydrolase 4 family+++IPR000073///Alpha/beta hydrolase fold-1+++IPR000952///AB hydrolase 4, conserved site","[ABHD1_HUMAN|Reviewed]RecName: Full=Protein ABHD1 {ECO:0000305}; EC=3.1.1.-; AltName: Full=Alpha/beta hydrolase domain-containing protein 1 {ECO:0000305}; Short=Abhydrolase domain-containing protein 1 {ECO:0000312|HGNC:HGNC:17553}; AltName: Full=Lung alpha/beta hydrolase 1;+++[A0A140VJD1_HUMAN|Unreviewed]SubName: Full=Abhydrolase domain containing 1, isoform CRA_b {ECO:0000313|EMBL:EAX00632.1}; SubName: Full=Testicular tissue protein Li 5 {ECO:0000313|EMBL:AEE60918.1};+++[C9J8C2_HUMAN|Unreviewed]SubName: Full=Protein ABHD1 {ECO:0000313|Ensembl:ENSP00000397522}; Flags: Fragment;+++[F8WBB3_HUMAN|Unreviewed]SubName: Full=Abhydrolase domain containing 1, isoform CRA_d {ECO:0000313|EMBL:EAX00634.1}; SubName: Full=Protein ABHD1 {ECO:0000313|Ensembl:ENSP00000390390};"]
[84725,"'PLEKHA8'",128,233,180.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0005802///trans-Golgi network+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0000139///Golgi membrane","GO:0097001///ceramide binding+++GO:0017089///glycolipid transporter activity+++GO:0051861///glycolipid binding+++GO:0070273///phosphatidylinositol-4-phosphate binding+++GO:0120013///intermembrane lipid transfer activity+++GO:1902388///ceramide 1-phosphate transporter activity+++GO:0008289///lipid binding+++GO:1902387///ceramide 1-phosphate binding","GO:0035627///ceramide transport+++GO:0046836///glycolipid transport+++GO:0035621///ER to Golgi ceramide transport+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:1902389///ceramide 1-phosphate transport+++GO:0120009///intermembrane lipid transfer+++GO:0006869///lipid transport+++GO:0015031///protein transport","IPR014830///Glycolipid transfer protein domain+++IPR001849///Pleckstrin homology domain+++IPR036497///Glycolipid transfer protein superfamily+++IPR011993///PH-like domain superfamily","[PKHA8_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family A member 8; Short=PH domain-containing family A member 8; AltName: Full=Phosphatidylinositol-four-phosphate adapter protein 2; Short=FAPP-2; Short=Phosphoinositol 4-phosphate adapter protein 2; Short=hFAPP2; AltName: Full=Serologically defined breast cancer antigen NY-BR-86;+++[A0A087X1S6_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 8 {ECO:0000313|Ensembl:ENSP00000484427};+++[A0A2P1JJM6_HUMAN|Unreviewed]SubName: Full=Phosphatidylinositol 4-phosphate adaptor protein-2 {ECO:0000313|EMBL:AVN99637.1};+++[B5MDU3_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 8 {ECO:0000313|Ensembl:ENSP00000379558};+++[J3KQS5_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family A member 8 {ECO:0000313|Ensembl:ENSP00000407802}; Flags: Fragment;"]
[84769,"'MPV17L2'",610,543,576.5,"04146///Peroxisome","H00469///Mitochondrial DNA depletion syndrome (MDS)",null,null,"GO:0005737///cytoplasm+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit",null,"GO:0061668///mitochondrial ribosome assembly+++GO:0070131///positive regulation of mitochondrial translation","IPR007248///Mpv17/PMP22","[M17L2_HUMAN|Reviewed]RecName: Full=Mpv17-like protein 2;+++[A0A024R7K6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EAW84671.1};"]
[84792,"'FAM220A'",321,299,310,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus",null,null,"IPR029367///Small integral membrane protein 10+++IPR029155///SIPAR domain","[F220A_HUMAN|Reviewed]RecName: Full=Protein FAM220A; AltName: Full=STAT3-interacting protein as a repressor;+++[A0A0C4DGP1_HUMAN|Unreviewed]SubName: Full=Protein FAM220A {ECO:0000313|Ensembl:ENSP00000464009};+++[E9PQC6_HUMAN|Unreviewed]SubName: Full=Protein FAM220A {ECO:0000313|Ensembl:ENSP00000436886}; Flags: Fragment;+++[E9PQY0_HUMAN|Unreviewed]SubName: Full=Protein FAM220A {ECO:0000313|Ensembl:ENSP00000432444}; Flags: Fragment;"]
[84811,"'BUD13'",142,146,144,{"$nulls":4},"GO:0070274///RES complex+++GO:0005634///nucleus+++GO:0005684///U2-type spliceosomal complex","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0000398///mRNA splicing, via spliceosome","IPR018609///Bud13","[BUD13_HUMAN|Reviewed]RecName: Full=BUD13 homolog;+++[H7C462_HUMAN|Unreviewed]SubName: Full=BUD13 homolog {ECO:0000313|Ensembl:ENSP00000415748}; Flags: Fragment;"]
[84844,"'PHF5A'",216,142,179,"03040///Spliceosome",null,"M00352///Spliceosome, U2-snRNP",null,"GO:0005681///spliceosomal complex+++GO:0005686///U2 snRNP+++GO:0016363///nuclear matrix+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005689///U12-type spliceosomal complex+++GO:0005654///nucleoplasm","GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0003723///RNA binding","GO:0006397///mRNA processing+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome","IPR005345///PHF5-like","[PHF5A_HUMAN|Reviewed]RecName: Full=PHD finger-like domain-containing protein 5A; Short=PHD finger-like domain protein 5A; AltName: Full=Splicing factor 3B-associated 14 kDa protein; Short=SF3b14b;+++[A0A024R1U2_HUMAN|Unreviewed]SubName: Full=PHD finger protein 5A, isoform CRA_a {ECO:0000313|EMBL:EAW60434.1};"]
[84875,"'PARP10'",690,642,666,{"$nulls":4},"GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0003950///NAD+ ADP-ribosyltransferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0003676///nucleic acid binding+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding","GO:1900045///negative regulation of protein K63-linked ubiquitination+++GO:0034356///NAD biosynthesis via nicotinamide riboside salvage pathway+++GO:0070213///protein auto-ADP-ribosylation+++GO:0010629///negative regulation of gene expression+++GO:0048147///negative regulation of fibroblast proliferation+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0010847///regulation of chromatin assembly+++GO:0070212///protein poly-ADP-ribosylation+++GO:0006471///protein ADP-ribosylation","IPR034464///PARP-10, RNA recognition motif 1 and 2+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR012317///Poly(ADP-ribose) polymerase, catalytic domain","[PAR10_HUMAN|Reviewed]RecName: Full=Poly [ADP-ribose] polymerase 10; Short=PARP-10; EC=2.4.2.30; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 10; Short=ARTD10;+++[A2RUM0_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[B4E0C4_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[E9PIA6_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000436697}; Flags: Fragment;+++[E9PIK9_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000435793}; Flags: Fragment;+++[E9PJI2_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000431818}; Flags: Fragment;+++[E9PK67_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[E9PLE8_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000435161}; Flags: Fragment;+++[E9PM86_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000431250}; Flags: Fragment;+++[E9PNI7_HUMAN|Unreviewed]RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114}; Short=PARP {ECO:0000256|RuleBase:RU362114}; EC=2.4.2.30 {ECO:0000256|RuleBase:RU362114};+++[E9PPE7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000432733};+++[E9PPU2_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000436333}; Flags: Fragment;+++[E9PPV8_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000436301}; Flags: Fragment;+++[E9PQQ6_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000434411}; Flags: Fragment;+++[E9PSE7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000434005}; Flags: Fragment;+++[E9PSG8_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000433990}; Flags: Fragment;+++[F8W8G7_HUMAN|Unreviewed]SubName: Full=Poly [ADP-ribose] polymerase 10 {ECO:0000313|Ensembl:ENSP00000314320}; Flags: Fragment;"]
[84897,"'TBRG1'",370,381,375.5,{"$nulls":4},"GO:0005634///nucleus","GO:0005515///protein binding","GO:0007050///cell cycle arrest+++GO:0050821///protein stabilization+++GO:1990173///protein localization to nucleoplasm+++GO:0006260///DNA replication+++GO:0008285///negative regulation of cell proliferation+++GO:0007049///cell cycle","IPR003888///FY-rich, N-terminal+++IPR003889///FY-rich, C-terminal","[TBRG1_HUMAN|Reviewed]RecName: Full=Transforming growth factor beta regulator 1; AltName: Full=Nuclear interactor of ARF and Mdm2;+++[A0A024R3K3_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta regulator 1, isoform CRA_a {ECO:0000313|EMBL:EAW67590.1};+++[E9PI10_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta regulator 1 {ECO:0000313|Ensembl:ENSP00000436599};+++[E9PK87_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta regulator 1 {ECO:0000313|Ensembl:ENSP00000435448}; Flags: Fragment;+++[F8W6N5_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta regulator 1 {ECO:0000313|Ensembl:ENSP00000284290};+++[Q05BL0_HUMAN|Unreviewed]SubName: Full=TBRG1 protein {ECO:0000313|EMBL:AAH41043.1};+++[Q6GPH2_HUMAN|Unreviewed]SubName: Full=TBRG1 protein {ECO:0000313|EMBL:AAH73160.1}; Flags: Fragment;+++[Q96LV8_HUMAN|Unreviewed]SubName: Full=TBRG1 protein {ECO:0000313|EMBL:AAH32312.1}; SubName: Full=cDNA FLJ25020 fis, clone CBL01662 {ECO:0000313|EMBL:BAB71559.1};"]
[84913,"'ATOH8'",54,30,42,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0033613///activating transcription factor binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0070888///E-box binding+++GO:0046983///protein dimerization activity+++GO:0003700///DNA-binding transcription factor activity+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding","GO:0045893///positive regulation of transcription, DNA-templated+++GO:1902895///positive regulation of pri-miRNA transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0060395///SMAD protein signal transduction+++GO:0010595///positive regulation of endothelial cell migration+++GO:0001704///formation of primary germ layer+++GO:0045603///positive regulation of endothelial cell differentiation+++GO:0030154///cell differentiation+++GO:0001937///negative regulation of endothelial cell proliferation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0010629///negative regulation of gene expression+++GO:0006355///regulation of transcription, DNA-templated+++GO:0051450///myoblast proliferation+++GO:0035148///tube formation+++GO:0007399///nervous system development","IPR032660///Protein atonal homologue 8+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain+++IPR036638///Helix-loop-helix DNA-binding domain superfamily","[ATOH8_HUMAN|Reviewed]RecName: Full=Protein atonal homolog 8; AltName: Full=Class A basic helix-loop-helix protein 21; Short=bHLHa21; AltName: Full=Helix-loop-helix protein hATH-6 {ECO:0000312|EMBL:AAO85773.1}; Short=hATH6 {ECO:0000303|PubMed:24463812};+++[D6W5L8_HUMAN|Unreviewed]SubName: Full=Atonal homolog 8 (Drosophila), isoform CRA_a {ECO:0000313|EMBL:EAW99482.1};"]
[84930,"'MASTL'",84,94,89,null,"H00978///Thrombocytopenia (THC)",null,null,"GO:0032154///cleavage furrow+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton","GO:0051721///protein phosphatase 2A binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0006468///protein phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007147///female meiosis II+++GO:0051301///cell division+++GO:0018105///peptidyl-serine phosphorylation+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0016310///phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","IPR000719///Protein kinase domain+++IPR000961///AGC-kinase, C-terminal+++IPR011009///Protein kinase-like domain superfamily+++IPR037638///Serine/threonine-protein kinase greatwall, catalytic domain+++IPR008271///Serine/threonine-protein kinase, active site","[GWL_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase greatwall; Short=GW; Short=GWL; Short=hGWL; EC=2.7.11.1; AltName: Full=Microtubule-associated serine/threonine-protein kinase-like; Short=MAST-L;+++[A0A087WUU7_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase greatwall {ECO:0000313|Ensembl:ENSP00000478938}; Flags: Fragment;"]
[84948,"'TIGD5'",189,195,192,{"$nulls":4},"GO:0005634///nucleus+++GO:0005575///cellular_component+++GO:0030479///actin cortical patch+++GO:0005884///actin filament","GO:0005515///protein binding+++GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0051015///actin filament binding+++GO:0003676///nucleic acid binding","GO:0051666///actin cortical patch localization+++GO:0008150///biological_process+++GO:0000147///actin cortical patch assembly+++GO:0030048///actin filament-based movement+++GO:0051127///positive regulation of actin nucleation+++GO:0006897///endocytosis","IPR007889///DNA binding HTH domain, Psq-type+++IPR004875///DDE superfamily endonuclease domain+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR009057///Homeobox-like domain superfamily+++IPR006600///HTH CenpB-type DNA-binding domain","[TIGD5_HUMAN|Reviewed]RecName: Full=Tigger transposable element-derived protein 5;"]
[84964,"'ALKBH6'",460,332,396,{"$nulls":4},"GO:0005925///focal adhesion+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0016491///oxidoreductase activity+++GO:0005515///protein binding+++GO:0051213///dioxygenase activity","GO:0055114///oxidation-reduction process","IPR005123///Oxoglutarate/iron-dependent dioxygenase+++IPR032862///Alpha-ketoglutarate-dependent dioxygenase alkB homologue 6+++IPR037151///Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily+++IPR027450///Alpha-ketoglutarate-dependent dioxygenase AlkB-like","[ALKB6_HUMAN|Reviewed]RecName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6; EC=1.14.11.-; AltName: Full=Alkylated DNA repair protein alkB homolog 6;+++[B4E3P3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52298 {ECO:0000313|EMBL:BAG65555.1};+++[E9PI76_HUMAN|Unreviewed]SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|Ensembl:ENSP00000436742};+++[H0YD66_HUMAN|Unreviewed]SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|Ensembl:ENSP00000433085}; Flags: Fragment;+++[H0YD83_HUMAN|Unreviewed]SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|Ensembl:ENSP00000433156}; Flags: Fragment;+++[H0YDL7_HUMAN|Unreviewed]SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|Ensembl:ENSP00000433885}; Flags: Fragment;+++[H0YEC4_HUMAN|Unreviewed]SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|Ensembl:ENSP00000435496}; Flags: Fragment;+++[H0YEM5_HUMAN|Unreviewed]SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|Ensembl:ENSP00000436156}; Flags: Fragment;+++[S4R3C7_HUMAN|Unreviewed]SubName: Full=Alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 {ECO:0000313|Ensembl:ENSP00000474158};"]
[8499,"'PPFIA2'",4,1,2.5,"00640///Propanoate metabolism+++04140///Autophagy - animal+++04137///Mitophagy - animal+++01100///Metabolic pathways",null,null,"R00926///Propionyladenylate:CoA propionyltransferase Propionyladenylate + CoA <=> AMP + Propanoyl-CoA+++R01354///ATP:propanoate adenylyltransferase ATP + Propanoate <=> Diphosphate + Propionyladenylate+++R00925///Propanoate:CoA ligase (AMP-forming) ATP + Propanoate + CoA <=> AMP + Diphosphate + Propanoyl-CoA","GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0048786///presynaptic active zone+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse","GO:0005515///protein binding+++GO:0099181///structural constituent of presynapse","GO:0007160///cell-matrix adhesion+++GO:0099172///presynapse organization+++GO:2000300///regulation of synaptic vesicle exocytosis","IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR029515///LAR-interacting protein, Liprin+++IPR037621///Liprin-alpha, SAM domain repeat 2+++IPR037622///Liprin-alpha, SAM domain repeat 3+++IPR037620///Liprin-alpha, SAM domain repeat 1+++IPR001660///Sterile alpha motif domain+++IPR030441///Liprin-alpha-2","[LIPA2_HUMAN|Reviewed]RecName: Full=Liprin-alpha-2; AltName: Full=Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2; Short=PTPRF-interacting protein alpha-2;+++[B7Z7Y5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59641, highly similar to Liprin-alpha-2 {ECO:0000313|EMBL:BAH13771.1};+++[F8VU88_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447918}; Flags: Fragment;+++[F8VWG6_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449821};+++[F8VWR9_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449469}; Flags: Fragment;+++[F8VYK7_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000448941}; Flags: Fragment;+++[F8W1Y8_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447792}; Flags: Fragment;+++[G3V200_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449558};+++[H0YH95_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000446555}; Flags: Fragment;+++[H0YHJ4_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447189}; Flags: Fragment;+++[H0YHK3_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000447273};+++[H0YIJ4_HUMAN|Unreviewed]SubName: Full=Liprin-alpha-2 {ECO:0000313|Ensembl:ENSP00000449524}; Flags: Fragment;+++[Q4LE62_HUMAN|Unreviewed]SubName: Full=PPFIA2 variant protein {ECO:0000313|EMBL:BAE06091.1}; Flags: Fragment;"]
[8502,"'PKP4'",668,836,752,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0001533///cornified envelope+++GO:0072686///mitotic spindle+++GO:0005911///cell-cell junction+++GO:0005634///nucleus+++GO:0030054///cell junction+++GO:0051233///spindle midzone+++GO:0048471///perinuclear region of cytoplasm+++GO:0000922///spindle pole+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0005819///spindle+++GO:0005856///cytoskeleton+++GO:0030057///desmosome+++GO:0014069///postsynaptic density+++GO:0016020///membrane+++GO:0005913///cell-cell adherens junction+++GO:0005737///cytoplasm+++GO:0030496///midbody+++GO:0044291///cell-cell contact zone+++GO:0005886///plasma membrane","GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0007267///cell-cell signaling+++GO:0070268///cornification+++GO:0031424///keratinization+++GO:0043547///positive regulation of GTPase activity+++GO:0032467///positive regulation of cytokinesis+++GO:0030155///regulation of cell adhesion+++GO:0007155///cell adhesion+++GO:0098609///cell-cell adhesion+++GO:0007043///cell-cell junction assembly","IPR016024///Armadillo-type fold+++IPR000225///Armadillo+++IPR028443///Plakophilin-4+++IPR028435///Plakophilin/Delta catenin+++IPR011989///Armadillo-like helical","[PKP4_HUMAN|Reviewed]RecName: Full=Plakophilin-4; AltName: Full=p0071;+++[A0A0D9SF60_HUMAN|Unreviewed]SubName: Full=Plakophilin-4 {ECO:0000313|Ensembl:ENSP00000486320};+++[E7EMY7_HUMAN|Unreviewed]SubName: Full=Plakophilin-4 {ECO:0000313|Ensembl:ENSP00000392515};+++[E7EP40_HUMAN|Unreviewed]SubName: Full=Plakophilin-4 {ECO:0000313|Ensembl:ENSP00000391658};+++[E7EST6_HUMAN|Unreviewed]SubName: Full=Plakophilin-4 {ECO:0000313|Ensembl:ENSP00000393872};+++[E9PHJ1_HUMAN|Unreviewed]SubName: Full=Plakophilin-4 {ECO:0000313|Ensembl:ENSP00000407218};+++[H0YFB1_HUMAN|Unreviewed]SubName: Full=Plakophilin-4 {ECO:0000313|Ensembl:ENSP00000437815}; Flags: Fragment;+++[Q4W5T8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PKP4 {ECO:0000313|EMBL:AAY62612.1}; Flags: Fragment;+++[Q53TM5_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein PKP4 {ECO:0000313|EMBL:AAY14929.1}; Flags: Fragment;"]
[8517,"'IKBKG'",769,719,744,"05221///Acute myeloid leukemia+++04920///Adipocytokine signaling pathway+++04668///TNF signaling pathway+++05212///Pancreatic cancer+++04658///Th1 and Th2 cell differentiation+++04062///Chemokine signaling pathway+++05222///Small cell lung cancer+++04622///RIG-I-like receptor signaling pathway+++05161///Hepatitis B+++05220///Chronic myeloid leukemia+++05203///Viral carcinogenesis+++04623///Cytosolic DNA-sensing pathway+++05160///Hepatitis C+++05418///Fluid shear stress and atherosclerosis+++04620///Toll-like receptor signaling pathway+++01523///Antifolate resistance+++05169///Epstein-Barr virus infection+++04380///Osteoclast differentiation+++04659///Th17 cell differentiation+++04014///Ras signaling pathway+++04064///NF-kappa B signaling pathway+++04625///C-type lectin receptor signaling pathway+++05340///Primary immunodeficiency+++04151///PI3K-Akt signaling pathway+++04662///B cell receptor signaling pathway+++05166///HTLV-I infection+++05131///Shigellosis+++05142///Chagas disease (American trypanosomiasis)+++04657///IL-17 signaling pathway+++05165///Human papillomavirus infection+++04210///Apoptosis+++05167///Kaposi's sarcoma-associated herpesvirus infection+++05145///Toxoplasmosis+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05200///Pathways in cancer+++05163///Human cytomegalovirus infection+++04010///MAPK signaling pathway+++05168///Herpes simplex infection+++04621///NOD-like receptor signaling pathway+++04660///T cell receptor signaling pathway+++05215///Prostate cancer","H01245///Immunodeficiency without anhidrotic ectodermal dysplasia+++H00645///Incontinentia pigmenti+++H00540///Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodeficiency (OLEDAID)+++H00095///Ectodermal dysplasia associated immunodeficiency (EDA-ID)","M00686///Toll-like receptor signaling",null,"GO:0005829///cytosol+++GO:0000151///ubiquitin ligase complex+++GO:0000922///spindle pole+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0008385///IkappaB kinase complex+++GO:0005634///nucleus+++GO:0005622///intracellular+++GO:0072686///mitotic spindle","GO:0042975///peroxisome proliferator activated receptor binding+++GO:0042803///protein homodimerization activity+++GO:0046982///protein heterodimerization activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:1990450///linear polyubiquitin binding+++GO:0046872///metal ion binding+++GO:0019904///protein domain specific binding+++GO:0016301///kinase activity+++GO:0070530///K63-linked polyubiquitin modification-dependent protein binding+++GO:0042802///identical protein binding","GO:0002756///MyD88-independent toll-like receptor signaling pathway+++GO:0016239///positive regulation of macroautophagy+++GO:0007249///I-kappaB kinase/NF-kappaB signaling+++GO:0006955///immune response+++GO:0051403///stress-activated MAPK cascade+++GO:0016579///protein deubiquitination+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0050852///T cell receptor signaling pathway+++GO:0043123///positive regulation of I-kappaB kinase/NF-kappaB signaling+++GO:0016032///viral process+++GO:1901215///negative regulation of neuron death+++GO:0006954///inflammatory response+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0002223///stimulatory C-type lectin receptor signaling pathway+++GO:0016310///phosphorylation+++GO:0007254///JNK cascade+++GO:0051650///establishment of vesicle localization+++GO:0043276///anoikis+++GO:0070423///nucleotide-binding oligomerization domain containing signaling pathway+++GO:0009615///response to virus+++GO:0000187///activation of MAPK activity+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006915///apoptotic process+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0035666///TRIF-dependent toll-like receptor signaling pathway+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0045087///innate immune response","IPR021063///NF-kappa-B essential modulator NEMO, N-terminal+++IPR032419///NF-kappa-B essential modulator NEMO, CC2-LZ domain+++IPR034735///NEMO, Zinc finger","[NEMO_HUMAN|Reviewed]RecName: Full=NF-kappa-B essential modulator; Short=NEMO; AltName: Full=FIP-3; AltName: Full=IkB kinase-associated protein 1; Short=IKKAP1; AltName: Full=Inhibitor of nuclear factor kappa-B kinase subunit gamma; Short=I-kappa-B kinase subunit gamma; Short=IKK-gamma; Short=IKKG; Short=IkB kinase subunit gamma; AltName: Full=NF-kappa-B essential modifier;+++[A0A087WUW6_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000478979};+++[A0A087WV30_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000479144}; Flags: Fragment;+++[A0A087WWQ9_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000480431};+++[A0A087X0G7_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000483381};+++[A0A087X1B1_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000484023};+++[A0A087X1K7_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000484275}; Flags: Fragment;+++[C9J2V2_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000398579}; Flags: Fragment;+++[C9JCG6_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000395205}; Flags: Fragment;+++[C9JH59_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000390368}; Flags: Fragment;+++[C9JN51_HUMAN|Unreviewed]SubName: Full=NF-kappa-B essential modulator {ECO:0000313|Ensembl:ENSP00000394934}; Flags: Fragment;+++[D3DWY0_HUMAN|Unreviewed]SubName: Full=Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b {ECO:0000313|EMBL:EAW72680.1};+++[D3DWY2_HUMAN|Unreviewed]SubName: Full=Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_a {ECO:0000313|EMBL:EAW72678.1};"]
[85313,"'PPIL4'",254,281,267.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003755///peptidyl-prolyl cis-trans isomerase activity+++GO:0016853///isomerase activity+++GO:0003723///RNA binding","GO:1901407///regulation of phosphorylation of RNA polymerase II C-terminal domain+++GO:0000413///protein peptidyl-prolyl isomerization","IPR002130///Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR035542///Cyclophilin-RNA interacting protein+++IPR000504///RNA recognition motif domain+++IPR029000///Cyclophilin-like domain superfamily+++IPR024936///Cyclophilin-type peptidyl-prolyl cis-trans isomerase+++IPR035538///PPIL4-like, cyclophilin domain","[PPIL4_HUMAN|Reviewed]RecName: Full=Peptidyl-prolyl cis-trans isomerase-like 4; Short=PPIase; EC=5.2.1.8; AltName: Full=Cyclophilin-like protein PPIL4; AltName: Full=Rotamase PPIL4;+++[Q32Q83_HUMAN|Unreviewed]SubName: Full=PPIL4 protein {ECO:0000313|EMBL:AAI07685.1}; Flags: Fragment;+++[Q5T4S2_HUMAN|Unreviewed]SubName: Full=Peptidyl-prolyl cis-trans isomerase-like 4 {ECO:0000313|Ensembl:ENSP00000344128};+++[Q6P392_HUMAN|Unreviewed]SubName: Full=PPIL4 protein {ECO:0000313|EMBL:AAH64134.1}; Flags: Fragment;"]
[85366,"'MYLK2'",7,2,4.5,"04921///Oxytocin signaling pathway+++04611///Platelet activation+++04022///cGMP-PKG signaling pathway+++04810///Regulation of actin cytoskeleton+++04020///Calcium signaling pathway+++04270///Vascular smooth muscle contraction+++04971///Gastric acid secretion+++04510///Focal adhesion+++04371///Apelin signaling pathway","H00801///Familial thoracic aortic aneurysm and dissection (TAAD)",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0030017///sarcomere","GO:0004687///myosin light chain kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0005516///calmodulin binding+++GO:0016301///kinase activity+++GO:0004683///calmodulin-dependent protein kinase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0032027///myosin light chain binding+++GO:0004674///protein serine/threonine kinase activity","GO:0055008///cardiac muscle tissue morphogenesis+++GO:0016310///phosphorylation+++GO:0006468///protein phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0007274///neuromuscular synaptic transmission+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0006941///striated muscle contraction+++GO:0014816///skeletal muscle satellite cell differentiation+++GO:0035914///skeletal muscle cell differentiation+++GO:0032971///regulation of muscle filament sliding+++GO:0060048///cardiac muscle contraction+++GO:0010628///positive regulation of gene expression","IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily","[MYLK2_HUMAN|Reviewed]RecName: Full=Myosin light chain kinase 2, skeletal/cardiac muscle; Short=MLCK2; EC=2.7.11.18;"]
[85416,"'ZIC5'",0,1,0.5,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding","GO:0007275///multicellular organism development+++GO:0007399///nervous system development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030154///cell differentiation","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZIC5_HUMAN|Reviewed]RecName: Full=Zinc finger protein ZIC 5; AltName: Full=Zinc finger protein of the cerebellum 5;"]
[85450,"'ITPRIP'",751,743,747,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"IPR024810///Mab-21 domain+++IPR024797///Inositol 1,4,5-trisphosphate receptor-interacting protein+++IPR026250///Inositol 1,4,5-trisphosphate receptor-interacting protein family","[IPRI_HUMAN|Reviewed]RecName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein; AltName: Full=Protein DANGER; Flags: Precursor;+++[X6RK76_HUMAN|Unreviewed]SubName: Full=Inositol 1,4,5-trisphosphate receptor-interacting protein {ECO:0000313|Ensembl:ENSP00000414141}; Flags: Fragment;"]
[85465,"'SELENOI'",182,243,212.5,"01110///Biosynthesis of secondary metabolites+++00564///Glycerophospholipid metabolism+++00565///Ether lipid metabolism+++01100///Metabolic pathways+++00440///Phosphonate and phosphinate metabolism",null,"M00092///Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE","R02057///CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1,2-Diacyl-sn-glycerol <=> CMP + Phosphatidylethanolamine+++R06364///CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase   CDP-ethanolamine + 1-Alkyl-2-acylglycerol <=> CMP + 1-Alkyl-2-acylglycerophosphoethanolamine+++R07384///O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine+++R04920///CMP-2-aminoethylphosphonate:1,2-diacylglycerol (2-aminoethylphosphonyl)transferase   CMP-2-aminoethylphosphonate + 1,2-Diacyl-sn-glycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate","GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0016020///membrane","GO:0004307///ethanolaminephosphotransferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016780///phosphotransferase activity, for other substituted phosphate groups+++GO:0016740///transferase activity","GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0008654///phospholipid biosynthetic process+++GO:0006629///lipid metabolic process","IPR000462///CDP-alcohol phosphatidyltransferase+++IPR014472///Choline/ethanolamine phosphotransferase","[EPT1_HUMAN|Reviewed]RecName: Full=Ethanolaminephosphotransferase 1 {ECO:0000305}; Short=hEPT1; EC=2.7.8.1; AltName: Full=Selenoprotein I {ECO:0000303|PubMed:27645994, ECO:0000312|HGNC:HGNC:29361}; Short=SelI {ECO:0000303|PubMed:27645994};+++[A0A087WW58_HUMAN|Unreviewed]SubName: Full=Ethanolaminephosphotransferase 1 {ECO:0000313|Ensembl:ENSP00000479973};+++[C9J9I1_HUMAN|Unreviewed]SubName: Full=Selenoprotein I {ECO:0000313|EMBL:EAX00692.1};+++[C9JAG1_HUMAN|Unreviewed]SubName: Full=Ethanolaminephosphotransferase 1 {ECO:0000313|Ensembl:ENSP00000391804}; Flags: Fragment;+++[C9JEZ2_HUMAN|Unreviewed]SubName: Full=Ethanolaminephosphotransferase 1 {ECO:0000313|Ensembl:ENSP00000415280}; Flags: Fragment;+++[G1UI38_HUMAN|Unreviewed]SubName: Full=Ethanolaminephosphotransferase 1 {ECO:0000313|EMBL:BAK64161.1}; Flags: Fragment;+++[Q8WU57_HUMAN|Unreviewed]SubName: Full=SELI protein {ECO:0000313|EMBL:AAH21229.1}; SubName: Full=Selenoprotein I {ECO:0000313|EMBL:EAX00693.1};"]
[8559,"'PRPF18'",198.36,146.75,172.555,"03040///Spliceosome",{"$nulls":3},"GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071021///U2-type post-spliceosomal complex+++GO:0005681///spliceosomal complex+++GO:0005682///U5 snRNP+++GO:0005634///nucleus+++GO:0016607///nuclear speck","GO:0000386///second spliceosomal transesterification activity","GO:0000350///generation of catalytic spliceosome for second transesterification step+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0071048///nuclear retention of unspliced pre-mRNA at the site of transcription","IPR014906///Pre-mRNA processing factor 4 (PRP4)-like+++IPR039979///Pre-mRNA-splicing factor 18+++IPR004098///Prp18+++IPR036285///PRP4-like superfamily","[PRP18_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor 18; AltName: Full=PRP18 homolog; Short=hPRP18;+++[L8E7W4_HUMAN|Unreviewed]SubName: Full=Alternative protein PRPF18 {ECO:0000313|EMBL:CCQ43229.1};+++[Q5T9P7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor 18 {ECO:0000313|Ensembl:ENSP00000392142}; Flags: Fragment;+++[Q5T9P8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor 18 {ECO:0000313|Ensembl:ENSP00000367824}; Flags: Fragment;"]
[8575,"'PRKRA'",403,381,392,{"$nulls":4},"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0070578///RISC-loading complex+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0043565///sequence-specific DNA binding+++GO:0019899///enzyme binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003725///double-stranded RNA binding+++GO:0070883///pre-miRNA binding+++GO:0016301///kinase activity+++GO:0042803///protein homodimerization activity+++GO:0008047///enzyme activator activity+++GO:0003723///RNA binding","GO:0050821///protein stabilization+++GO:0007389///pattern specification process+++GO:0007420///brain development+++GO:0006955///immune response+++GO:0031047///gene silencing by RNA+++GO:0043085///positive regulation of catalytic activity+++GO:0007275///multicellular organism development+++GO:0007601///visual perception+++GO:0031054///pre-miRNA processing+++GO:0042474///middle ear morphogenesis+++GO:0043010///camera-type eye development+++GO:0008285///negative regulation of cell proliferation+++GO:0021854///hypothalamus development+++GO:0006468///protein phosphorylation+++GO:0009615///response to virus+++GO:0048705///skeletal system morphogenesis+++GO:0030422///production of siRNA involved in RNA interference+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016032///viral process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:0043583///ear development+++GO:0016310///phosphorylation+++GO:0034599///cellular response to oxidative stress+++GO:0035196///production of miRNAs involved in gene silencing by miRNA+++GO:0010586///miRNA metabolic process+++GO:0060173///limb development+++GO:0042473///outer ear morphogenesis","IPR033363///Interferon-inducible double-stranded RNA-dependent protein kinase activator A+++IPR032478///Staufen, C-terminal+++IPR014720///Double-stranded RNA-binding domain","[PRKRA_HUMAN|Reviewed]RecName: Full=Interferon-inducible double-stranded RNA-dependent protein kinase activator A; AltName: Full=PKR-associated protein X; AltName: Full=PKR-associating protein X; AltName: Full=Protein activator of the interferon-induced protein kinase; AltName: Full=Protein kinase, interferon-inducible double-stranded RNA-dependent activator;+++[B4DJC7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60590, highly similar to Interferon-inducible double strandedRNA-dependent protein kinase activator A {ECO:0000313|EMBL:BAG58789.1};+++[C9JMM3_HUMAN|Unreviewed]SubName: Full=Interferon-inducible double-stranded RNA-dependent protein kinase activator A {ECO:0000313|Ensembl:ENSP00000408668}; Flags: Fragment;+++[F8WEG8_HUMAN|Unreviewed]SubName: Full=Interferon-inducible double-stranded RNA-dependent protein kinase activator A {ECO:0000313|Ensembl:ENSP00000388455};+++[G5E9Q4_HUMAN|Unreviewed]SubName: Full=Interferon-inducible double-stranded RNA-dependent protein kinase activator A {ECO:0000313|Ensembl:ENSP00000408029}; SubName: Full=Protein kinase, interferon-inducible double stranded RNA dependent activator, isoform CRA_d {ECO:0000313|EMBL:EAX11037.1};"]
[8609,"'KLF7'",714,988,851,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0008270///zinc ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003713///transcription coactivator activity+++GO:0046872///metal ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0050796///regulation of insulin secretion+++GO:0007411///axon guidance+++GO:1904178///negative regulation of adipose tissue development+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0045604///regulation of epidermal cell differentiation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007409///axonogenesis+++GO:0048813///dendrite morphogenesis","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[KLF7_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 7; AltName: Full=Ubiquitous krueppel-like factor;+++[A0A024R3X8_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 7 (Ubiquitous), isoform CRA_a {ECO:0000313|EMBL:EAW70401.1};+++[C9JX20_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 7 {ECO:0000313|Ensembl:ENSP00000413590}; Flags: Fragment;+++[E7EQY2_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 7 {ECO:0000313|Ensembl:ENSP00000397245}; Flags: Fragment;+++[E7EUU0_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 7 {ECO:0000313|Ensembl:ENSP00000392015}; Flags: Fragment;+++[E9PHC9_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 7 {ECO:0000313|Ensembl:ENSP00000412950};+++[L8E9A5_HUMAN|Unreviewed]SubName: Full=Alternative protein KLF7 {ECO:0000313|EMBL:CCQ42933.1};+++[Q4ZG79_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KLF7 {ECO:0000313|EMBL:AAX88867.1}; Flags: Fragment;+++[Q53TP3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KLF7 {ECO:0000313|EMBL:AAY15081.1}; Flags: Fragment;"]
[8626,"'TP63'",12,20.46,16.23,"05206///MicroRNAs in cancer+++04391///Hippo signaling pathway - fly+++04214///Apoptosis - fly","H00471///Split-hand/foot malformation (SHFM)+++H00641///ADULT syndrome+++H00752///Ankyloblepharon-ctodermal defects-cleft lip/palate (AEC) syndrome and Rapp-Hodgkin syndrome+++H00516///Cleft lip and/or cleft palate+++H00640///Limb-mammary syndrome+++H00638///Ectrodactyly-ectodermal dysplasia cleft-palate syndrome (EEC syndrome)",null,null,"GO:0005794///Golgi apparatus+++GO:0005791///rough endoplasmic reticulum+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0000790///nuclear chromatin+++GO:0005739///mitochondrion","GO:0003684///damaged DNA binding+++GO:0003690///double-stranded DNA binding+++GO:0097371///MDM2/MDM4 family protein binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0019904///protein domain specific binding+++GO:0050699///WW domain binding+++GO:0046872///metal ion binding+++GO:0042802///identical protein binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity+++GO:0003682///chromatin binding+++GO:0002039///p53 binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0005515///protein binding","GO:0051289///protein homotetramerization+++GO:0001736///establishment of planar polarity+++GO:0048807///female genitalia morphogenesis+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0061436///establishment of skin barrier+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0042771///intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator+++GO:0006915///apoptotic process+++GO:0007275///multicellular organism development+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030859///polarized epithelial cell differentiation+++GO:0009954///proximal/distal pattern formation+++GO:0010259///multicellular organism aging+++GO:0031069///hair follicle morphogenesis+++GO:0030850///prostate gland development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0051262///protein tetramerization+++GO:0010838///positive regulation of keratinocyte proliferation+++GO:1904888///cranial skeletal system development+++GO:0098773///skin epidermis development+++GO:0033147///negative regulation of intracellular estrogen receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0060513///prostatic bud formation+++GO:0007568///aging+++GO:0045617///negative regulation of keratinocyte differentiation+++GO:0030855///epithelial cell differentiation+++GO:1902808///positive regulation of cell cycle G1/S phase transition+++GO:0007049///cell cycle+++GO:0030216///keratinocyte differentiation+++GO:0002064///epithelial cell development+++GO:0048485///sympathetic nervous system development+++GO:0051402///neuron apoptotic process+++GO:0001501///skeletal system development+++GO:0009887///animal organ morphogenesis+++GO:0007219///Notch signaling pathway+++GO:0045669///positive regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2000773///negative regulation of cellular senescence+++GO:0008283///cell proliferation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042475///odontogenesis of dentin-containing tooth+++GO:0007283///spermatogenesis+++GO:0007499///ectoderm and mesoderm interaction+++GO:0007569///cell aging+++GO:0060529///squamous basal epithelial stem cell differentiation involved in prostate gland acinus development+++GO:1904674///positive regulation of somatic stem cell population maintenance+++GO:0060197///cloacal septation+++GO:1900740///positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway+++GO:0007389///pattern specification process+++GO:0036342///post-anal tail morphogenesis+++GO:0009913///epidermal cell differentiation+++GO:0008544///epidermis development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0043589///skin morphogenesis+++GO:0010481///epidermal cell division+++GO:0010482///regulation of epidermal cell division+++GO:0001942///hair follicle development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0042981///regulation of apoptotic process+++GO:0032502///developmental process+++GO:2001235///positive regulation of apoptotic signaling pathway+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006338///chromatin remodeling+++GO:0035115///embryonic forelimb morphogenesis+++GO:0030154///cell differentiation+++GO:0030326///embryonic limb morphogenesis+++GO:0001302///replicative cell aging+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:0001738///morphogenesis of a polarized epithelium+++GO:2000381///negative regulation of mesoderm development","IPR037611///Tumour protein p63, SAM domain+++IPR010991///p53, tetramerisation domain+++IPR032645///Tumour protein p63+++IPR008967///p53-like transcription factor, DNA-binding+++IPR002117///p53 tumour suppressor family+++IPR011615///p53, DNA-binding domain+++IPR036674///p53-like tetramerisation domain superfamily+++IPR012346///p53/RUNT-type transcription factor, DNA-binding domain superfamily+++IPR013761///Sterile alpha motif/pointed domain superfamily+++IPR001660///Sterile alpha motif domain","[P63_HUMAN|Reviewed]RecName: Full=Tumor protein 63; Short=p63; AltName: Full=Chronic ulcerative stomatitis protein; Short=CUSP; AltName: Full=Keratinocyte transcription factor KET; AltName: Full=Transformation-related protein 63; Short=TP63; AltName: Full=Tumor protein p73-like; Short=p73L; AltName: Full=p40; AltName: Full=p51;+++[A0A0S2Z4N5_HUMAN|Unreviewed]SubName: Full=Tumor protein p63 isoform 1 {ECO:0000313|EMBL:ALQ33893.1}; SubName: Full=Tumor protein p73-like, isoform CRA_a {ECO:0000313|EMBL:EAW78112.1}; Flags: Fragment;+++[A0A0S2Z4N6_HUMAN|Unreviewed]SubName: Full=Tumor protein p63 isoform 2 {ECO:0000313|EMBL:ALQ33894.1}; Flags: Fragment;+++[A0A141PNN3_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[A0A141PNN4_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[B7Z8X6_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[C9D7C9_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[C9D7D0_HUMAN|Unreviewed]RecName: Full=Cellular tumor antigen p53 {ECO:0000256|RuleBase:RU003304};+++[C9JW72_HUMAN|Unreviewed]SubName: Full=Tumor protein 63 {ECO:0000313|Ensembl:ENSP00000401661}; Flags: Fragment;"]
[8642,"'DCHS1'",778,1043,910.5,"04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species","H01868///Mitral valve prolapse+++H01393///Van Maldergem syndrome (VMLDS/VMS)",null,null,"GO:0016342///catenin complex+++GO:0005913///cell-cell adherens junction+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0045177///apical part of cell+++GO:0009986///cell surface","GO:0046872///metal ion binding+++GO:0008092///cytoskeletal protein binding+++GO:0005509///calcium ion binding+++GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity","GO:0003192///mitral valve formation+++GO:0007389///pattern specification process+++GO:0016477///cell migration+++GO:0035329///hippo signaling+++GO:0021915///neural tube development+++GO:0043931///ossification involved in bone maturation+++GO:0007157///heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0001658///branching involved in ureteric bud morphogenesis+++GO:0072006///nephron development+++GO:0036342///post-anal tail morphogenesis+++GO:0072137///condensed mesenchymal cell proliferation+++GO:0022008///neurogenesis+++GO:0048565///digestive tract development+++GO:0072659///protein localization to plasma membrane+++GO:0016339///calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules+++GO:0007155///cell adhesion+++GO:0034332///adherens junction organization+++GO:0003183///mitral valve morphogenesis+++GO:0098609///cell-cell adhesion+++GO:0003273///cell migration involved in endocardial cushion formation+++GO:0003007///heart morphogenesis+++GO:0090102///cochlea development+++GO:0044331///cell-cell adhesion mediated by cadherin+++GO:0001822///kidney development+++GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0009653///anatomical structure morphogenesis+++GO:0007043///cell-cell junction assembly","IPR020894///Cadherin conserved site+++IPR015919///Cadherin-like superfamily+++IPR002126///Cadherin-like","[PCD16_HUMAN|Reviewed]RecName: Full=Protocadherin-16; AltName: Full=Cadherin-19; AltName: Full=Cadherin-25; AltName: Full=Fibroblast cadherin-1; AltName: Full=Protein dachsous homolog 1; Flags: Precursor;"]
[8661,"'EIF3A'",2300,2531,2415.5,"03013///RNA transport",{"$nulls":3},"GO:0033290///eukaryotic 48S preinitiation complex+++GO:0016282///eukaryotic 43S preinitiation complex+++GO:0014069///postsynaptic density+++GO:0005730///nucleolus+++GO:0016020///membrane+++GO:0005852///eukaryotic translation initiation factor 3 complex+++GO:0005737///cytoplasm+++GO:0043614///multi-eIF complex+++GO:0005874///microtubule+++GO:0005634///nucleus+++GO:0071540///eukaryotic translation initiation factor 3 complex, eIF3e+++GO:0005829///cytosol+++GO:0071541///eukaryotic translation initiation factor 3 complex, eIF3m","GO:0030971///receptor tyrosine kinase binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003743///translation initiation factor activity+++GO:0005198///structural molecule activity","GO:0006413///translational initiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0001732///formation of cytoplasmic translation initiation complex+++GO:0002188///translation reinitiation+++GO:0075522///IRES-dependent viral translational initiation+++GO:0075525///viral translational termination-reinitiation","IPR000717///Proteasome component (PCI) domain+++IPR027512///Eukaryotic translation initiation factor 3 subunit A","[EIF3A_HUMAN|Reviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit A {ECO:0000255|HAMAP-Rule:MF_03000}; Short=eIF3a {ECO:0000255|HAMAP-Rule:MF_03000}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255|HAMAP-Rule:MF_03000}; AltName: Full=eIF-3-theta {ECO:0000255|HAMAP-Rule:MF_03000}; AltName: Full=eIF3 p167; AltName: Full=eIF3 p180; AltName: Full=eIF3 p185;+++[Q05BS0_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit A {ECO:0000256|SAAS:SAAS01037641}; Flags: Fragment;+++[Q24JU4_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit A {ECO:0000256|HAMAP-Rule:MF_03000, ECO:0000256|SAAS:SAAS01037641}; Short=eIF3a {ECO:0000256|HAMAP-Rule:MF_03000}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 10 {ECO:0000256|HAMAP-Rule:MF_03000}; AltName: Full=eIF-3-theta {ECO:0000256|HAMAP-Rule:MF_03000};+++[Q3B770_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit A {ECO:0000256|SAAS:SAAS01037641}; Flags: Fragment;+++[Q6P1R0_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit A {ECO:0000256|SAAS:SAAS01037641}; Flags: Fragment;+++[Q6ZNE1_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit A {ECO:0000256|HAMAP-Rule:MF_03000, ECO:0000256|SAAS:SAAS01037641}; Short=eIF3a {ECO:0000256|HAMAP-Rule:MF_03000}; AltName: Full=Eukaryotic translation initiation factor 3 subunit 10 {ECO:0000256|HAMAP-Rule:MF_03000}; AltName: Full=eIF-3-theta {ECO:0000256|HAMAP-Rule:MF_03000};+++[Q7Z5T5_HUMAN|Unreviewed]RecName: Full=Eukaryotic translation initiation factor 3 subunit A {ECO:0000256|SAAS:SAAS01037641}; Flags: Fragment;"]
[8676,"'STX11'",17,20,18.5,"04130///SNARE interactions in vesicular transport","H00109///Familial hemophagocytic lymphohistiocytosis (FHPL)",null,null,"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0008021///synaptic vesicle+++GO:0012505///endomembrane system+++GO:0005794///Golgi apparatus+++GO:0048787///presynaptic active zone membrane+++GO:0042734///presynaptic membrane+++GO:0005886///plasma membrane+++GO:0031201///SNARE complex","GO:0000149///SNARE binding+++GO:0005515///protein binding+++GO:0005484///SNAP receptor activity","GO:0006887///exocytosis+++GO:0015031///protein transport+++GO:0006886///intracellular protein transport+++GO:0006906///vesicle fusion+++GO:0016192///vesicle-mediated transport+++GO:0061025///membrane fusion+++GO:0048278///vesicle docking+++GO:0031629///synaptic vesicle fusion to presynaptic active zone membrane","IPR006012///Syntaxin/epimorphin, conserved site+++IPR006011///Syntaxin, N-terminal domain+++IPR000727///Target SNARE coiled-coil homology domain+++IPR028672///Syntaxin-11+++IPR010989///SNARE","[STX11_HUMAN|Reviewed]RecName: Full=Syntaxin-11;"]
[87,"'ACTN1'",44244,46860,45552,"05146///Amoebiasis+++04810///Regulation of actin cytoskeleton+++04670///Leukocyte transendothelial migration+++04510///Focal adhesion+++04530///Tight junction+++04520///Adherens junction+++05203///Viral carcinogenesis+++05322///Systemic lupus erythematosus","H01740///Macrothrombocytopenia+++H00626///Focal segmental glomerulosclerosis",null,null,"GO:0030017///sarcomere+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0098978///glutamatergic synapse+++GO:0005576///extracellular region+++GO:0005903///brush border+++GO:0005911///cell-cell junction+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005622///intracellular+++GO:0030054///cell junction+++GO:0005615///extracellular space+++GO:0005925///focal adhesion+++GO:0005884///actin filament+++GO:0031143///pseudopodium+++GO:0031093///platelet alpha granule lumen+++GO:0001725///stress fiber+++GO:0070062///extracellular exosome+++GO:0005916///fascia adherens+++GO:0001726///ruffle+++GO:0030018///Z disc","GO:0003779///actin binding+++GO:0003725///double-stranded RNA binding+++GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:0017166///vinculin binding+++GO:0099186///structural constituent of postsynapse+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0005509///calcium ion binding+++GO:0051015///actin filament binding+++GO:0042803///protein homodimerization activity+++GO:0046872///metal ion binding+++GO:0044325///ion channel binding","GO:0048041///focal adhesion assembly+++GO:0030220///platelet formation+++GO:0042981///regulation of apoptotic process+++GO:0007015///actin filament organization+++GO:0099173///postsynapse organization+++GO:1903508///positive regulation of nucleic acid-templated transcription+++GO:0002576///platelet degranulation+++GO:0036344///platelet morphogenesis+++GO:0070527///platelet aggregation+++GO:0051017///actin filament bundle assembly+++GO:0051271///negative regulation of cellular component movement+++GO:0051639///actin filament network formation+++GO:0051764///actin crosslink formation+++GO:0030168///platelet activation","IPR018159///Spectrin/alpha-actinin+++IPR011992///EF-hand domain pair+++IPR018247///EF-Hand 1, calcium-binding site+++IPR026921///Alpha-actinin 1+++IPR001589///Actinin-type actin-binding domain, conserved site+++IPR002017///Spectrin repeat+++IPR014837///EF-hand, Ca insensitive+++IPR002048///EF-hand domain+++IPR001715///Calponin homology domain+++IPR036872///CH domain superfamily","[ACTN1_HUMAN|Reviewed]RecName: Full=Alpha-actinin-1; AltName: Full=Alpha-actinin cytoskeletal isoform; AltName: Full=F-actin cross-linking protein; AltName: Full=Non-muscle alpha-actinin-1;+++[A0A024R694_HUMAN|Unreviewed]SubName: Full=Actinin, alpha 1, isoform CRA_a {ECO:0000313|EMBL:EAW80976.1};+++[A1L0V1_HUMAN|Unreviewed]SubName: Full=ACTN1 protein {ECO:0000313|EMBL:AAI27125.1}; Flags: Fragment;+++[G3V2E8_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000450618}; Flags: Fragment;+++[G3V2N5_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000450764}; Flags: Fragment;+++[G3V2W4_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000450903}; Flags: Fragment;+++[G3V2X9_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000450925}; Flags: Fragment;+++[G3V380_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000451086}; Flags: Fragment;+++[G3V5M4_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000452423}; Flags: Fragment;+++[H0YJ11_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000450625}; Flags: Fragment;+++[H0YJW3_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000452254}; Flags: Fragment;+++[H7C5W8_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000444422}; Flags: Fragment;+++[H9KV75_HUMAN|Unreviewed]SubName: Full=Alpha-actinin-1 {ECO:0000313|Ensembl:ENSP00000366035};+++[Q5ZEZ4_HUMAN|Unreviewed]SubName: Full=Alpha-actinin 1 {ECO:0000313|EMBL:CAH59747.2}; Flags: Fragment;"]
[8718,"'TNFRSF25'",107,123,115,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0005031///tumor necrosis factor-activated receptor activity+++GO:0038023///signaling receptor activity","GO:0006915///apoptotic process+++GO:0007166///cell surface receptor signaling pathway+++GO:0042981///regulation of apoptotic process+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0007165///signal transduction+++GO:0097190///apoptotic signaling pathway","IPR001849///Pleckstrin homology domain+++IPR022329///Tumour necrosis factor receptor 25+++IPR011029///Death-like domain superfamily+++IPR035899///Dbl homology (DH) domain superfamily+++IPR011993///PH-like domain superfamily+++IPR000488///Death domain+++IPR000219///Dbl homology (DH) domain+++IPR001368///TNFR/NGFR cysteine-rich region+++IPR034050///Tumor necrosis factor receptor 25, N-terminal+++IPR029071///Ubiquitin-like domain superfamily","[TNR25_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor receptor superfamily member 25; AltName: Full=Apo-3; AltName: Full=Apoptosis-inducing receptor AIR; AltName: Full=Apoptosis-mediating receptor DR3; AltName: Full=Apoptosis-mediating receptor TRAMP; AltName: Full=Death receptor 3; AltName: Full=Lymphocyte-associated receptor of death; Short=LARD; AltName: Full=Protein WSL; AltName: Full=Protein WSL-1; Flags: Precursor;+++[A0A0C4DGF3_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 25 {ECO:0000313|Ensembl:ENSP00000434129};+++[A5LIN1_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 25 deletion mutant {ECO:0000313|EMBL:BAF64192.1};+++[K7EJY9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 25 {ECO:0000313|Ensembl:ENSP00000465381}; Flags: Fragment;"]
[8736,"'MYOM1'",9,30,19.5,{"$nulls":4},"GO:0005865///striated muscle thin filament+++GO:0005737///cytoplasm+++GO:0005863///striated muscle myosin thick filament+++GO:0032982///myosin filament+++GO:0030018///Z disc+++GO:0030017///sarcomere+++GO:0031430///M band","GO:0042803///protein homodimerization activity+++GO:0019900///kinase binding+++GO:0051371///muscle alpha-actinin binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding+++GO:0008307///structural constituent of muscle+++GO:0051015///actin filament binding","GO:0050714///positive regulation of protein secretion+++GO:0010628///positive regulation of gene expression+++GO:0055003///cardiac myofibril assembly+++GO:0030241///skeletal muscle myosin thick filament assembly+++GO:0048739///cardiac muscle fiber development+++GO:0045214///sarcomere organization+++GO:0030240///skeletal muscle thin filament assembly+++GO:0002074///extraocular skeletal muscle development+++GO:0055008///cardiac muscle tissue morphogenesis+++GO:0006936///muscle contraction+++GO:0010737///protein kinase A signaling","IPR007110///Immunoglobulin-like domain+++IPR036116///Fibronectin type III superfamily+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013098///Immunoglobulin I-set+++IPR003599///Immunoglobulin subtype+++IPR003598///Immunoglobulin subtype 2+++IPR013783///Immunoglobulin-like fold+++IPR003961///Fibronectin type III","[MYOM1_HUMAN|Reviewed]RecName: Full=Myomesin-1; AltName: Full=190 kDa connectin-associated protein; AltName: Full=190 kDa titin-associated protein; AltName: Full=Myomesin family member 1;+++[A0A1B1HY11_HUMAN|Unreviewed]SubName: Full=Myomesin 1 variant 1 isoform a {ECO:0000313|EMBL:ANR02585.1}; Flags: Fragment;+++[A0A1B1HY12_HUMAN|Unreviewed]SubName: Full=Myomesin 1 variant 1 isoform a {ECO:0000313|EMBL:ANR02584.1}; Flags: Fragment;+++[A0A1B1HY21_HUMAN|Unreviewed]SubName: Full=Myomesin 1 variant 1 isoform a {ECO:0000313|EMBL:ANR02586.1}; Flags: Fragment;+++[A0A1B1HY23_HUMAN|Unreviewed]SubName: Full=Myomesin 1 variant 1 isoform a {ECO:0000313|EMBL:ANR02587.1}; Flags: Fragment;+++[A8MX12_HUMAN|Unreviewed]SubName: Full=Myomesin-1 {ECO:0000313|Ensembl:ENSP00000383413};+++[J3KRK2_HUMAN|Unreviewed]SubName: Full=Myomesin-1 {ECO:0000313|Ensembl:ENSP00000462039}; Flags: Fragment;+++[L8E928_HUMAN|Unreviewed]SubName: Full=Alternative protein MYOM1 {ECO:0000313|EMBL:CCQ43236.1};"]
[8760,"'CDS2'",813,786,799.5,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++01110///Biosynthesis of secondary metabolites",null,"M00093///Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE","R01799///CTP:phosphatidate cytidyltransferase   CTP + Phosphatidate <=> Diphosphate + CDP-diacylglycerol","GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005783///endoplasmic reticulum","GO:0004605///phosphatidate cytidylyltransferase activity+++GO:0016779///nucleotidyltransferase activity+++GO:0016740///transferase activity+++GO:0016772///transferase activity, transferring phosphorus-containing groups","GO:0008654///phospholipid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006655///phosphatidylglycerol biosynthetic process+++GO:0016024///CDP-diacylglycerol biosynthetic process","IPR000374///Phosphatidate cytidylyltransferase+++IPR016720///Phosphatidate cytidylyltransferase, eukaryota","[CDS2_HUMAN|Reviewed]RecName: Full=Phosphatidate cytidylyltransferase 2; EC=2.7.7.41; AltName: Full=CDP-DAG synthase 2; AltName: Full=CDP-DG synthase 2; AltName: Full=CDP-diacylglycerol synthase 2; Short=CDS 2; AltName: Full=CDP-diglyceride pyrophosphorylase 2; AltName: Full=CDP-diglyceride synthase 2; AltName: Full=CTP:phosphatidate cytidylyltransferase 2;"]
[8784,"'TNFRSF18'",9,1,5,"04060///Cytokine-cytokine receptor interaction",{"$nulls":3},"GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005887///integral component of plasma membrane","GO:0005515///protein binding+++GO:0005031///tumor necrosis factor-activated receptor activity","GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0045589///regulation of regulatory T cell differentiation+++GO:0006915///apoptotic process+++GO:0007165///signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0042531///positive regulation of tyrosine phosphorylation of STAT protein+++GO:0045785///positive regulation of cell adhesion+++GO:0002687///positive regulation of leukocyte migration","IPR022318///Tumour necrosis factor receptor 18+++IPR001368///TNFR/NGFR cysteine-rich region+++IPR034018///Tumour necrosis factor receptor 18, N-terminal","[TNR18_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor receptor superfamily member 18; AltName: Full=Activation-inducible TNFR family receptor; AltName: Full=Glucocorticoid-induced TNFR-related protein; AltName: CD_antigen=CD357; Flags: Precursor;+++[A0A0R7FDM1_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 18 isoform 4 {ECO:0000313|EMBL:AKO62650.1};+++[A8WFP4_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily, member 18 {ECO:0000313|EMBL:AAI52387.1}; Flags: Fragment;+++[J3KT02_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor receptor superfamily member 18 {ECO:0000313|Ensembl:ENSP00000462735};"]
[8800,"'PEX11A'",20,19,19.5,"04146///Peroxisome",{"$nulls":3},"GO:0005777///peroxisome+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0005779///integral component of peroxisomal membrane+++GO:0016021///integral component of membrane+++GO:0005778///peroxisomal membrane","GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0019216///regulation of lipid metabolic process+++GO:0050873///brown fat cell differentiation+++GO:0007031///peroxisome organization+++GO:0044375///regulation of peroxisome size+++GO:0016557///peroxisome membrane biogenesis+++GO:0007165///signal transduction+++GO:0016559///peroxisome fission","IPR008733///Peroxisomal biogenesis factor 11","[PX11A_HUMAN|Reviewed]RecName: Full=Peroxisomal membrane protein 11A; Short=HsPEX11p; AltName: Full=28 kDa peroxisomal integral membrane protein; Short=PMP28; AltName: Full=Peroxin-11A; AltName: Full=Peroxisomal biogenesis factor 11A; AltName: Full=Protein PEX11 homolog alpha; Short=PEX11-alpha;+++[B2R8C6_HUMAN|Unreviewed]SubName: Full=Peroxisomal biogenesis factor 11A {ECO:0000313|EMBL:EAX02062.1}; SubName: Full=cDNA FLJ10553 fis, clone NT2RP2002325, highly similar to Peroxisomal membrane protein 11A {ECO:0000313|EMBL:BAG50908.1}; SubName: Full=cDNA, FLJ93834, Homo sapiens peroxisomal biogenesis factor 11A (PEX11A), mRNA {ECO:0000313|EMBL:BAG36123.1};+++[B4DMF6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50808, highly similar to Peroxisomal membrane protein 11A {ECO:0000313|EMBL:BAG59868.1};+++[H0YMC7_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein 11A {ECO:0000313|Ensembl:ENSP00000453552};+++[H0YN61_HUMAN|Unreviewed]SubName: Full=Peroxisomal membrane protein 11A {ECO:0000313|Ensembl:ENSP00000453878};+++[Q29R61_HUMAN|Unreviewed]SubName: Full=PEX11A protein {ECO:0000313|EMBL:AAI14385.1};"]
[8818,"'DPM2'",1105,929,1017,"00510///N-Glycan biosynthesis+++00563///Glycosylphosphatidylinositol (GPI)-anchor biosynthesis+++01100///Metabolic pathways","H00118///Congenital disorders of glycosylation (CDG) type I",null,"R01009///GDPmannose:dolichyl-phosphate O-beta-D-mannosyltransferase   GDP-mannose + Dolichyl phosphate <=> GDP + Dolichyl phosphate D-mannose+++R05916///UDP-N-acetyl-D-glucosamine + 1-Phosphatidyl-D-myo-inositol <=> UDP + G00143","GO:0033185///dolichol-phosphate-mannose synthase complex+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0000506///glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex","GO:0004582///dolichyl-phosphate beta-D-mannosyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0016757///transferase activity, transferring glycosyl groups","GO:0016254///preassembly of GPI anchor in ER membrane+++GO:0031647///regulation of protein stability+++GO:0035269///protein O-linked mannosylation+++GO:0006506///GPI anchor biosynthetic process+++GO:0050790///regulation of catalytic activity+++GO:0006486///protein glycosylation+++GO:0019348///dolichol metabolic process","IPR009914///Dolichol phosphate-mannose biosynthesis regulatory","[DPM2_HUMAN|Reviewed]RecName: Full=Dolichol phosphate-mannose biosynthesis regulatory protein; AltName: Full=Dolichol-phosphate mannose synthase subunit 2; Short=DPM synthase subunit 2;+++[Q5T9C7_HUMAN|Unreviewed]SubName: Full=Dolichol phosphate-mannose biosynthesis regulatory protein {ECO:0000313|Ensembl:ENSP00000362202};+++[Q96BP5_HUMAN|Unreviewed]SubName: Full=DPM2 protein {ECO:0000313|EMBL:AAH15374.1}; SubName: Full=cDNA, FLJ92403, Homo sapiens dolichyl-phosphate mannosyltransferase polypeptide 2,regulatory subunit (DPM2), transcript variant 2, mRNA {ECO:0000313|EMBL:BAG35057.1};"]
[8835,"'SOCS2'",51,32,41.5,"04917///Prolactin signaling pathway+++04910///Insulin signaling pathway+++04630///Jak-STAT signaling pathway+++04930///Type II diabetes mellitus","H01762///Muscle glycogen storage disease+++H00069///Glycogen storage diseases (GSD)+++H01951///Glycogen storage disease type X","M00684///JAK-STAT signaling+++M00388///ECS complex","R01518///D-phosphoglycerate 2,3-phosphomutase 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate","GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005942///phosphatidylinositol 3-kinase complex","GO:0005070///SH3/SH2 adaptor activity+++GO:0005515///protein binding+++GO:0046935///1-phosphatidylinositol-3-kinase regulator activity+++GO:0005131///growth hormone receptor binding+++GO:0005159///insulin-like growth factor receptor binding+++GO:0008269///JAK pathway signal transduction adaptor activity","GO:0040014///regulation of multicellular organism growth+++GO:0040015///negative regulation of multicellular organism growth+++GO:0046426///negative regulation of JAK-STAT cascade+++GO:0007595///lactation+++GO:0032870///cellular response to hormone stimulus+++GO:0043066///negative regulation of apoptotic process+++GO:0001558///regulation of cell growth+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0009966///regulation of signal transduction+++GO:0016567///protein ubiquitination+++GO:0035556///intracellular signal transduction+++GO:0045666///positive regulation of neuron differentiation+++GO:0040008///regulation of growth+++GO:0038111///interleukin-7-mediated signaling pathway+++GO:0007259///JAK-STAT cascade+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0046627///negative regulation of insulin receptor signaling pathway+++GO:0060749///mammary gland alveolus development+++GO:0009968///negative regulation of signal transduction+++GO:0009967///positive regulation of signal transduction+++GO:0032355///response to estradiol+++GO:0060396///growth hormone receptor signaling pathway+++GO:0043687///post-translational protein modification","IPR000980///SH2 domain+++IPR035862///SOCS2, SH2 domain+++IPR036860///SH2 domain superfamily+++IPR036036///SOCS box-like domain superfamily+++IPR028410///Suppressor of cytokine signalling 2+++IPR001496///SOCS box domain","[SOCS2_HUMAN|Reviewed]RecName: Full=Suppressor of cytokine signaling 2; Short=SOCS-2; AltName: Full=Cytokine-inducible SH2 protein 2; Short=CIS-2; AltName: Full=STAT-induced STAT inhibitor 2; Short=SSI-2;+++[A0A024RBD2_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine signaling 2, isoform CRA_a {ECO:0000313|EMBL:EAW97493.1};+++[B5BU82_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine signaling-2 {ECO:0000313|EMBL:BAG70132.1};+++[F8VRV3_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine-signaling 2 {ECO:0000313|Ensembl:ENSP00000448611}; Flags: Fragment;+++[F8VS53_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine-signaling 2 {ECO:0000313|Ensembl:ENSP00000448709};+++[F8VU91_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine-signaling 2 {ECO:0000313|Ensembl:ENSP00000447902}; Flags: Fragment;+++[S4R3W1_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine-signaling 2 {ECO:0000313|Ensembl:ENSP00000474805}; Flags: Fragment;+++[S4R3Z4_HUMAN|Unreviewed]SubName: Full=Suppressor of cytokine-signaling 2 {ECO:0000313|Ensembl:ENSP00000474888}; Flags: Fragment;"]
[8853,"'ASAP2'",1176,1912,1544,"04666///Fc gamma R-mediated phagocytosis+++04144///Endocytosis",{"$nulls":3},"GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0032580///Golgi cisterna membrane","GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity","IPR001849///Pleckstrin homology domain+++IPR027267///AH/BAR domain superfamily+++IPR037278///ARFGAP/RecO-like zinc finger+++IPR037844///ASAP, PH domain+++IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR036028///SH3-like domain superfamily+++IPR002110///Ankyrin repeat+++IPR035677///ASAP2, SH3 domain+++IPR001164///Arf GTPase activating protein+++IPR038508///ArfGAP domain superfamily+++IPR011993///PH-like domain superfamily+++IPR001452///SH3 domain","[ASAP2_HUMAN|Reviewed]RecName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; AltName: Full=Development and differentiation-enhancing factor 2; AltName: Full=Paxillin-associated protein with ARF GAP activity 3; Short=PAG3; AltName: Full=Pyk2 C-terminus-associated protein; Short=PAP;+++[A0A286YFG8_HUMAN|Unreviewed]SubName: Full=Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000493293}; Flags: Fragment;+++[Q53R39_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DDEF2 {ECO:0000313|EMBL:AAY24112.1}; Flags: Fragment;+++[Q53RS3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DDEF2 {ECO:0000313|EMBL:AAY14856.1}; Flags: Fragment;+++[Q53RT9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DDEF2 {ECO:0000313|EMBL:AAY14904.1}; Flags: Fragment;"]
[8877,"'SPHK1'",680,498,589,"04072///Phospholipase D signaling pathway+++04371///Apelin signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04020///Calcium signaling pathway+++04370///VEGF signaling pathway+++05152///Tuberculosis+++01100///Metabolic pathways+++04071///Sphingolipid signaling pathway+++00600///Sphingolipid metabolism",null,"M00100///Sphingosine degradation","R01926///ATP:sphingosine 1-phosphotransferase; sphingosine   Sphingosine + ATP <=> Sphingosine 1-phosphate + ADP+++R02976///ATP:sphinganine 1-phosphotransferase   ATP + Sphinganine <=> ADP + Sphinganine 1-phosphate","GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005634///nucleus","GO:0038036///sphingosine-1-phosphate receptor activity+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0003951///NAD+ kinase activity+++GO:0051721///protein phosphatase 2A binding+++GO:0005516///calmodulin binding+++GO:0017050///D-erythro-sphingosine kinase activity+++GO:0008481///sphinganine kinase activity+++GO:0016301///kinase activity+++GO:0000287///magnesium ion binding","GO:1901224///positive regulation of NIK/NF-kappaB signaling+++GO:0006457///protein folding+++GO:0007420///brain development+++GO:0019722///calcium-mediated signaling+++GO:0010800///positive regulation of peptidyl-threonine phosphorylation+++GO:0046512///sphingosine biosynthetic process+++GO:0035556///intracellular signal transduction+++GO:0043066///negative regulation of apoptotic process+++GO:0006670///sphingosine metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0046521///sphingoid catabolic process+++GO:0046834///lipid phosphorylation+++GO:0032651///regulation of interleukin-1 beta production+++GO:0030307///positive regulation of cell growth+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0030148///sphingolipid biosynthetic process+++GO:0016310///phosphorylation+++GO:0031398///positive regulation of protein ubiquitination+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0045987///positive regulation of smooth muscle contraction+++GO:0045766///positive regulation of angiogenesis+++GO:0007165///signal transduction+++GO:0001568///blood vessel development+++GO:0003376///sphingosine-1-phosphate receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0030335///positive regulation of cell migration","IPR016064///NAD kinase/diacylglycerol kinase-like domain superfamily+++IPR001206///Diacylglycerol kinase, catalytic domain+++IPR017438///Inorganic polyphosphate/ATP-NAD kinase, N-terminal","[SPHK1_HUMAN|Reviewed]RecName: Full=Sphingosine kinase 1; Short=SK 1; Short=SPK 1; EC=2.7.1.91 {ECO:0000269|PubMed:10802064, ECO:0000269|PubMed:20577214, ECO:0000269|PubMed:23602659};+++[K7EJ32_HUMAN|Unreviewed]SubName: Full=Sphingosine kinase 1 {ECO:0000313|Ensembl:ENSP00000465002}; Flags: Fragment;+++[K7EMA4_HUMAN|Unreviewed]SubName: Full=Sphingosine kinase 1 {ECO:0000313|Ensembl:ENSP00000466422}; Flags: Fragment;+++[Q53ZR5_HUMAN|Unreviewed]SubName: Full=Sphingosine kinase 1 {ECO:0000313|EMBL:AAP35060.1}; SubName: Full=Sphingosine kinase 1, isoform CRA_a {ECO:0000313|EMBL:EAW89388.1}; SubName: Full=cDNA FLJ78254 {ECO:0000313|EMBL:BAF85303.1};+++[Q9BTG7_HUMAN|Unreviewed]SubName: Full=SPHK1 protein {ECO:0000313|EMBL:AAH04112.2}; Flags: Fragment;"]
[8893,"'EIF2B5'",282,249,265.5,"03013///RNA transport","H00869///Leukoencephalopathy with vanishing white matter",null,null,"GO:0005851///eukaryotic translation initiation factor 2B complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003743///translation initiation factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0031369///translation initiation factor binding","GO:0045948///positive regulation of translational initiation+++GO:0048708///astrocyte differentiation+++GO:0034976///response to endoplasmic reticulum stress+++GO:0009408///response to heat+++GO:0010226///response to lithium ion+++GO:0007568///aging+++GO:0006412///translation+++GO:0006413///translational initiation+++GO:0001541///ovarian follicle development+++GO:0042552///myelination+++GO:0014002///astrocyte development+++GO:0050852///T cell receptor signaling pathway+++GO:0009749///response to glucose+++GO:0043434///response to peptide hormone+++GO:0021766///hippocampus development+++GO:0043065///positive regulation of apoptotic process+++GO:0045727///positive regulation of translation+++GO:0014003///oligodendrocyte development","IPR003307///W2 domain+++IPR016021///MIF4G-like domain superfamily+++IPR029044///Nucleotide-diphospho-sugar transferases+++IPR035543///Translation initiation factor eIF-2B subunit epsilon, N-terminal+++IPR011004///Trimeric LpxA-like superfamily+++IPR001451///Hexapeptide repeat+++IPR016024///Armadillo-type fold","[EI2BE_HUMAN|Reviewed]RecName: Full=Translation initiation factor eIF-2B subunit epsilon; AltName: Full=eIF-2B GDP-GTP exchange factor subunit epsilon;+++[C9JRD9_HUMAN|Unreviewed]SubName: Full=Translation initiation factor eIF-2B subunit epsilon {ECO:0000313|Ensembl:ENSP00000414775};+++[H7C2X0_HUMAN|Unreviewed]SubName: Full=Translation initiation factor eIF-2B subunit epsilon {ECO:0000313|Ensembl:ENSP00000408198}; Flags: Fragment;"]
[8911,"'CACNA1I'",1,0,0.5,"04713///Circadian entrainment+++04927///Cortisol synthesis and secretion+++04925///Aldosterone synthesis and secretion+++04020///Calcium signaling pathway+++04010///MAPK signaling pathway+++04934///Cushing's syndrome",{"$nulls":3},"GO:0005891///voltage-gated calcium channel complex+++GO:0005886///plasma membrane","GO:0008332///low voltage-gated calcium channel activity+++GO:0005248///voltage-gated sodium channel activity+++GO:0005245///voltage-gated calcium channel activity","GO:0019228///neuronal action potential+++GO:0034765///regulation of ion transmembrane transport+++GO:0070509///calcium ion import+++GO:0030431///sleep+++GO:0086010///membrane depolarization during action potential+++GO:0007165///signal transduction+++GO:0045956///positive regulation of calcium ion-dependent exocytosis+++GO:0030317///flagellated sperm motility","IPR027359///Voltage-dependent channel domain superfamily+++IPR005445///Voltage-dependent calcium channel, T-type, alpha-1 subunit+++IPR005821///Ion transport domain+++IPR002077///Voltage-dependent calcium channel, alpha-1 subunit+++IPR030162///Voltage-dependent calcium channel, T-type, alpha-1I subunit","[CAC1I_HUMAN|Reviewed]RecName: Full=Voltage-dependent T-type calcium channel subunit alpha-1I; AltName: Full=Voltage-gated calcium channel subunit alpha Cav3.3; Short=Ca(v)3.3;"]
[8933,"'RTL8C'",9726,9521.01,9623.505,{"$nulls":4},"GO:0005575///cellular_component+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding","GO:0008150///biological_process","IPR031771///CAAX box protein 1+++IPR032567///LDOC1-related+++IPR032549///Domain of unknown function DUF4939","[CXX1_HUMAN|Reviewed]RecName: Full=CAAX box protein 1; AltName: Full=Cerebral protein 5; Flags: Precursor;+++[RTL8C_HUMAN|Reviewed]RecName: Full=Retrotransposon Gag-like protein 8B {ECO:0000312|HGNC:HGNC:2569}; AltName: Full=Mammalian retrotransposon derived protein 8C {ECO:0000312|HGNC:HGNC:2569};"]
[8971,"'H1FX'",865,818,841.5,{"$nulls":4},"GO:0000786///nucleosome+++GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005730///nucleolus","GO:0031492///nucleosomal DNA binding+++GO:0045296///cadherin binding+++GO:0003690///double-stranded DNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003723///RNA binding","GO:0016584///nucleosome positioning+++GO:0030261///chromosome condensation+++GO:0045910///negative regulation of DNA recombination+++GO:0031936///negative regulation of chromatin silencing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006334///nucleosome assembly","IPR005818///Linker histone H1/H5, domain H15+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR005819///Histone H5","[H1X_HUMAN|Reviewed]RecName: Full=Histone H1x;"]
[89839,"'ARHGAP11B'",1.38,0,0.69,{"$nulls":4},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0021987///cerebral cortex development+++GO:0043547///positive regulation of GTPase activity+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007165///signal transduction","IPR008936///Rho GTPase activation protein+++IPR000198///Rho GTPase-activating protein domain","[RHGBB_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 11B {ECO:0000305}; AltName: Full=Protein FAM7B1 {ECO:0000305}; AltName: Full=Rho-type GTPase-activating protein 11B {ECO:0000305};+++[A0A2X0SFT2_HUMAN|Unreviewed]SubName: Full=ARHGAP11B {ECO:0000313|EMBL:SPT35685.1}; Flags: Fragment;"]
[89886,"'SLAMF9'",2,0,1,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0003674///molecular_function","GO:0008150///biological_process","IPR013783///Immunoglobulin-like fold+++IPR007110///Immunoglobulin-like domain+++IPR036179///Immunoglobulin-like domain superfamily","[SLAF9_HUMAN|Reviewed]RecName: Full=SLAM family member 9; AltName: Full=CD2 family member 10; Short=CD2F-10; AltName: Full=CD84 homolog 1; Short=CD84-H1; Flags: Precursor;+++[Q6NSE6_HUMAN|Unreviewed]SubName: Full=SLAMF9 protein {ECO:0000313|EMBL:AAH70213.1};"]
[89887,"'ZNF628'",429,483,456,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZN628_HUMAN|Reviewed]RecName: Full=Zinc finger protein 628;+++[A0A087WSX5_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 628 {ECO:0000313|Ensembl:ENSP00000375598};+++[K7EL41_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 628 {ECO:0000313|Ensembl:ENSP00000465905}; Flags: Fragment;"]
[89953,"'KLC4'",475,385,430,"05132///Salmonella infection",{"$nulls":3},"GO:0005871///kinesin complex+++GO:0005874///microtubule+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0003777///microtubule motor activity","GO:0036498///IRE1-mediated unfolded protein response+++GO:0007131///reciprocal meiotic recombination","IPR002151///Kinesin light chain+++IPR019734///Tetratricopeptide repeat+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR015792///Kinesin light chain repeat","[KLC4_HUMAN|Reviewed]RecName: Full=Kinesin light chain 4; Short=KLC 4; AltName: Full=Kinesin-like protein 8;+++[A0A024RCZ8_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4, isoform CRA_a {ECO:0000313|EMBL:EAX04148.1};+++[C9J8T5_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4 {ECO:0000313|Ensembl:ENSP00000417652}; Flags: Fragment;+++[C9JQU1_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4 {ECO:0000313|Ensembl:ENSP00000420144}; Flags: Fragment;+++[C9JXT5_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4 {ECO:0000313|Ensembl:ENSP00000419102}; Flags: Fragment;+++[C9JZE5_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4 {ECO:0000313|Ensembl:ENSP00000419784}; Flags: Fragment;+++[C9K0D5_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4 {ECO:0000313|Ensembl:ENSP00000419634}; Flags: Fragment;+++[F8WCA4_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4 {ECO:0000313|Ensembl:ENSP00000418546};+++[H7C4M1_HUMAN|Unreviewed]SubName: Full=Kinesin light chain 4 {ECO:0000313|Ensembl:ENSP00000417620}; Flags: Fragment;"]
[90060,"'CCDC120'",165,241,203,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0030426///growth cone+++GO:0005856///cytoskeleton+++GO:0005768///endosome+++GO:0005814///centriole+++GO:0120103///centriolar subdistal appendage","GO:0005515///protein binding","GO:0008104///protein localization+++GO:0007275///multicellular organism development+++GO:0034454///microtubule anchoring at centrosome","IPR039108///Coiled-coil domain-containing protein 120+++IPR021774///Domain of unknown function DUF3338","[CC120_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 120;+++[S4R3T7_HUMAN|Unreviewed]SubName: Full=Coiled-coil domain-containing protein 120 {ECO:0000313|Ensembl:ENSP00000474713};"]
[90187,"'EMILIN3'",5,3,4,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0031012///extracellular matrix","GO:0005201///extracellular matrix structural constituent",null,"IPR011489///EMI domain","[EMIL3_HUMAN|Reviewed]RecName: Full=EMILIN-3; AltName: Full=EMILIN-5; AltName: Full=Elastin microfibril interface-located protein 3; Short=Elastin microfibril interfacer 3; AltName: Full=Elastin microfibril interface-located protein 5; Short=Elastin microfibril interfacer 5; Flags: Precursor;"]
[9025,"'RNF8'",168,131,149.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005694///chromosome+++GO:0000781///chromosome, telomeric region+++GO:0030496///midbody+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0035861///site of double-strand break","GO:0042802///identical protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0031625///ubiquitin protein ligase binding+++GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0043130///ubiquitin binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0033523///histone H2B ubiquitination+++GO:0036297///interstrand cross-link repair+++GO:0070936///protein K48-linked ubiquitination+++GO:0035093///spermatogenesis, exchange of chromosomal proteins+++GO:0033522///histone H2A ubiquitination+++GO:0006325///chromatin organization+++GO:0010212///response to ionizing radiation+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0070534///protein K63-linked ubiquitination+++GO:0043486///histone exchange+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0007049///cell cycle+++GO:0051865///protein autoubiquitination+++GO:0016567///protein ubiquitination+++GO:0045739///positive regulation of DNA repair+++GO:0006302///double-strand break repair+++GO:0045190///isotype switching+++GO:0051301///cell division+++GO:0007286///spermatid development+++GO:0006974///cellular response to DNA damage stimulus+++GO:0070535///histone H2A K63-linked ubiquitination+++GO:0034244///negative regulation of transcription elongation from RNA polymerase II promoter+++GO:0006281///DNA repair","IPR017907///Zinc finger, RING-type, conserved site+++IPR000253///Forkhead-associated (FHA) domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR008984///SMAD/FHA domain superfamily+++IPR001841///Zinc finger, RING-type+++IPR017335///E3 ubiquitin-protein ligase RNF8","[RNF8_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF8 {ECO:0000255|HAMAP-Rule:MF_03067}; Short=hRNF8; EC=2.3.2.27 {ECO:0000255|HAMAP-Rule:MF_03067}; AltName: Full=RING finger protein 8 {ECO:0000255|HAMAP-Rule:MF_03067}; AltName: Full=RING-type E3 ubiquitin transferase RNF8 {ECO:0000255|HAMAP-Rule:MF_03067};+++[C9J858_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF8 {ECO:0000313|Ensembl:ENSP00000417736}; Flags: Fragment;+++[F8WDH8_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF8 {ECO:0000313|Ensembl:ENSP00000420268};+++[F8WEW6_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF8 {ECO:0000313|Ensembl:ENSP00000419859};+++[H7C4L7_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF8 {ECO:0000313|Ensembl:ENSP00000417599}; Flags: Fragment;+++[L0R6N6_HUMAN|Unreviewed]SubName: Full=Alternative protein RNF8 {ECO:0000313|EMBL:CCO13805.1};"]
[90338,"'ZNF160'",161,207,184,"04137///Mitophagy - animal+++04140///Autophagy - animal","H01852///Postaxial polydactyly+++H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,null,"GO:0005615///extracellular space+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005576///extracellular region","GO:0008201///heparin binding+++GO:0016787///hydrolase activity+++GO:0042802///identical protein binding+++GO:0008233///peptidase activity+++GO:0005515///protein binding+++GO:0070009///serine-type aminopeptidase activity+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0004252///serine-type endopeptidase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008236///serine-type peptidase activity","GO:0030193///regulation of blood coagulation+++GO:0007596///blood coagulation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031639///plasminogen activation+++GO:0007599///hemostasis+++GO:0007597///blood coagulation, intrinsic pathway+++GO:0051919///positive regulation of fibrinolysis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030097///hemopoiesis+++GO:0006508///proteolysis","IPR036236///Zinc finger C2H2 superfamily+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR013087///Zinc finger C2H2-type","[ZN160_HUMAN|Reviewed]RecName: Full=Zinc finger protein 160; AltName: Full=Zinc finger protein HZF5; AltName: Full=Zinc finger protein Kr18; Short=HKr18;+++[A0A024R4Q2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160, isoform CRA_c {ECO:0000313|EMBL:EAW72114.1};+++[D6RB32_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|Ensembl:ENSP00000424479};+++[H0Y596_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|Ensembl:ENSP00000397401}; Flags: Fragment;+++[M0QXU9_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160 {ECO:0000313|Ensembl:ENSP00000469393}; Flags: Fragment;+++[M0QZ49_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160 {ECO:0000313|Ensembl:ENSP00000470305}; Flags: Fragment;+++[M0QZI7_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160, isoform CRA_b {ECO:0000313|EMBL:EAW72111.1};+++[M0R285_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 160 {ECO:0000313|Ensembl:ENSP00000472387}; Flags: Fragment;+++[Q9UEG0_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|EMBL:BAA20295.1}; Flags: Fragment;+++[X6R3B1_HUMAN|Unreviewed]SubName: Full=Coagulation factor XI {ECO:0000313|Ensembl:ENSP00000264691}; Flags: Fragment;"]
[90417,"'KNSTRN'",179,90,134.5,{"$nulls":4},"GO:0000775///chromosome, centromeric region+++GO:0000922///spindle pole+++GO:0035371///microtubule plus-end+++GO:0005856///cytoskeleton+++GO:0000776///kinetochore+++GO:0000777///condensed chromosome kinetochore+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005874///microtubule+++GO:0015630///microtubule cytoskeleton+++GO:0005694///chromosome+++GO:0072686///mitotic spindle+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0007051///spindle organization+++GO:0007049///cell cycle+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0007059///chromosome segregation+++GO:0051301///cell division+++GO:0000070///mitotic sister chromatid segregation","IPR033373///Small kinetochore-associated protein","[SKAP_HUMAN|Reviewed]RecName: Full=Small kinetochore-associated protein {ECO:0000303|PubMed:19667759}; Short=SKAP {ECO:0000303|PubMed:19667759}; AltName: Full=Kinetochore-localized astrin-binding protein {ECO:0000303|PubMed:21402792}; Short=Kinastrin {ECO:0000303|PubMed:21402792}; AltName: Full=Kinetochore-localized astrin/SPAG5-binding protein; AltName: Full=TRAF4-associated factor 1;+++[H0YKD4_HUMAN|Unreviewed]SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000452758}; Flags: Fragment;+++[H0YKF8_HUMAN|Unreviewed]SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000452788}; Flags: Fragment;+++[H0YLA7_HUMAN|Unreviewed]SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000453126}; Flags: Fragment;+++[H0YLH8_HUMAN|Unreviewed]SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000453213};+++[H0YM11_HUMAN|Unreviewed]SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000453421}; Flags: Fragment;+++[H0YN50_HUMAN|Unreviewed]SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000453867}; Flags: Fragment;+++[H0YNN6_HUMAN|Unreviewed]SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000454086}; Flags: Fragment;+++[V9GY01_HUMAN|Unreviewed]SubName: Full=Chromosome 15 open reading frame 23, isoform CRA_d {ECO:0000313|EMBL:EAW92412.1}; SubName: Full=Small kinetochore-associated protein {ECO:0000313|Ensembl:ENSP00000476263};"]
[9050,"'PSTPIP2'",310,330.01,320.005,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0008092///cytoskeletal protein binding+++GO:0051015///actin filament binding+++GO:0003779///actin binding+++GO:0005515///protein binding","GO:0007010///cytoskeleton organization+++GO:0030041///actin filament polymerization+++GO:0016477///cell migration","IPR030106///Proline-serine-threonine phosphatase-interacting protein 2+++IPR031160///F-BAR domain+++IPR027267///AH/BAR domain superfamily+++IPR001060///FCH domain","[PPIP2_HUMAN|Reviewed]RecName: Full=Proline-serine-threonine phosphatase-interacting protein 2; Short=PEST phosphatase-interacting protein 2;+++[A0A0S2Z4R2_HUMAN|Unreviewed]SubName: Full=Proline-serine-threonine phosphatase interacting protein 2 isoform 2 {ECO:0000313|EMBL:ALQ33914.1}; SubName: Full=Proline-serine-threonine phosphatase interacting protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX01467.1};+++[A0A0S2Z505_HUMAN|Unreviewed]SubName: Full=Proline-serine-threonine phosphatase interacting protein 2 isoform 3 {ECO:0000313|EMBL:ALQ33915.1}; SubName: Full=Proline-serine-threonine phosphatase interacting protein 2, isoform CRA_a {ECO:0000313|EMBL:EAX01466.1};+++[A0A0S2Z5F6_HUMAN|Unreviewed]SubName: Full=Proline-serine-threonine phosphatase interacting protein 2 isoform 1 {ECO:0000313|EMBL:ALQ33913.1}; Flags: Fragment;"]
[9057,"'SLC7A6'",848,1031,939.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016323///basolateral plasma membrane+++GO:0005887///integral component of plasma membrane","GO:0015297///antiporter activity+++GO:0022857///transmembrane transporter activity+++GO:0015179///L-amino acid transmembrane transporter activity+++GO:0015171///amino acid transmembrane transporter activity","GO:0050900///leukocyte migration+++GO:0065003///protein-containing complex assembly+++GO:0006520///cellular amino acid metabolic process+++GO:1902475///L-alpha-amino acid transmembrane transport+++GO:0006865///amino acid transport+++GO:0055085///transmembrane transport+++GO:0003333///amino acid transmembrane transport","IPR002293///Amino acid/polyamine transporter I","[YLAT2_HUMAN|Reviewed]RecName: Full=Y+L amino acid transporter 2; AltName: Full=Cationic amino acid transporter, y+ system; AltName: Full=Solute carrier family 7 member 6; AltName: Full=y(+)L-type amino acid transporter 2; Short=Y+LAT2; Short=y+LAT-2;+++[A0A024R719_HUMAN|Unreviewed]SubName: Full=Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 6, isoform CRA_a {ECO:0000313|EMBL:EAW83220.1};+++[A0AUM0_HUMAN|Unreviewed]SubName: Full=SLC7A6 protein {ECO:0000313|EMBL:AAI13101.1}; Flags: Fragment;+++[E7EPZ8_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000368448};+++[H3BNF5_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000454824};+++[H3BPK5_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000455357}; Flags: Fragment;+++[H3BPV6_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000455487}; Flags: Fragment;+++[H3BRZ8_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000456474}; Flags: Fragment;+++[H3BSB6_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000456629}; Flags: Fragment;+++[H3BSV7_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000456896}; Flags: Fragment;+++[H3BUA4_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000457550}; Flags: Fragment;+++[H3BUR2_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000457758}; Flags: Fragment;+++[J3QL60_HUMAN|Unreviewed]SubName: Full=Y+L amino acid transporter 2 {ECO:0000313|Ensembl:ENSP00000463394}; Flags: Fragment;"]
[90649,"'ZNF486'",32,35,33.5,"04140///Autophagy - animal+++04137///Mitophagy - animal","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005634///nucleus+++GO:0070062///extracellular exosome","GO:0003674///molecular_function+++GO:0003677///DNA binding+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0008150///biological_process+++GO:0006355///regulation of transcription, DNA-templated","IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN486_HUMAN|Reviewed]RecName: Full=Zinc finger protein 486; AltName: Full=KRAB domain only protein 2;+++[M0QXQ0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 486 {ECO:0000313|Ensembl:ENSP00000469306};+++[Q4G180_HUMAN|Unreviewed]SubName: Full=ZNF486 protein {ECO:0000313|EMBL:AAH27608.1}; Flags: Fragment;"]
[9079,"'LDB2'",0,1,0.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0000790///nuclear chromatin+++GO:1990907///beta-catenin-TCF complex+++GO:0005667///transcription factor complex+++GO:0005730///nucleolus+++GO:0031252///cell leading edge+++GO:0005886///plasma membrane","GO:0019899///enzyme binding+++GO:0043621///protein self-association+++GO:0003714///transcription corepressor activity+++GO:0003682///chromatin binding+++GO:0003712///transcription coregulator activity+++GO:0001102///RNA polymerase II activating transcription factor binding+++GO:0030274///LIM domain binding+++GO:0003677///DNA binding+++GO:0001158///enhancer sequence-specific DNA binding+++GO:0005515///protein binding+++GO:0042803///protein homodimerization activity","GO:0000972///transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery+++GO:0009948///anterior/posterior axis specification+++GO:0030334///regulation of cell migration+++GO:0051893///regulation of focal adhesion assembly+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0022607///cellular component assembly+++GO:0044089///positive regulation of cellular component biogenesis+++GO:0021549///cerebellum development+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021702///cerebellar Purkinje cell differentiation+++GO:0001942///hair follicle development+++GO:0010669///epithelial structure maintenance+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0043973///histone H3-K4 acetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0016055///Wnt signaling pathway+++GO:0030182///neuron differentiation+++GO:0001702///gastrulation with mouth forming second+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006366///transcription by RNA polymerase II+++GO:0006351///transcription, DNA-templated+++GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0045785///positive regulation of cell adhesion+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0035019///somatic stem cell population maintenance+++GO:0060322///head development+++GO:0043549///regulation of kinase activity","IPR030174///LIM domain-binding protein 2+++IPR029005///LIM-domain binding protein/SEUSS","[LDB2_HUMAN|Reviewed]RecName: Full=LIM domain-binding protein 2; Short=LDB-2; AltName: Full=Carboxyl-terminal LIM domain-binding protein 1; Short=CLIM-1; AltName: Full=LIM domain-binding factor CLIM1;+++[B7Z6D0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60147, highly similar to LIM domain-binding protein 2 {ECO:0000313|EMBL:BAH13216.1};+++[D6RAT1_HUMAN|Unreviewed]SubName: Full=LIM domain-binding protein 2 {ECO:0000313|Ensembl:ENSP00000421767}; Flags: Fragment;+++[E7EX95_HUMAN|Unreviewed]SubName: Full=LIM domain-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424770};+++[E9PFI4_HUMAN|Unreviewed]SubName: Full=LIM domain-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423963};+++[E9PGU0_HUMAN|Unreviewed]SubName: Full=LIM domain-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424676};+++[G5E9Y7_HUMAN|Unreviewed]SubName: Full=LIM domain binding 2, isoform CRA_b {ECO:0000313|EMBL:EAW92766.1}; SubName: Full=LIM domain-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422552};+++[H0YA09_HUMAN|Unreviewed]SubName: Full=LIM domain-binding protein 2 {ECO:0000313|Ensembl:ENSP00000425754}; Flags: Fragment;+++[Q4W5E7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LDB2 {ECO:0000313|EMBL:AAY40912.1}; Flags: Fragment;"]
[90864,"'SPSB3'",607,558,582.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0019005///SCF ubiquitin ligase complex","GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity","GO:0016567///protein ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043687///post-translational protein modification","IPR001870///B30.2/SPRY domain+++IPR001496///SOCS box domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR035754///SPRY domain-containing SOCS box protein 3, SPRY domain+++IPR003877///SPRY domain","[SPSB3_HUMAN|Reviewed]RecName: Full=SPRY domain-containing SOCS box protein 3; Short=SSB-3;+++[D3DU79_HUMAN|Unreviewed]SubName: Full=SplA/ryanodine receptor domain and SOCS box containing 3, isoform CRA_d {ECO:0000313|EMBL:EAW85623.1};+++[H3BP12_HUMAN|Unreviewed]SubName: Full=SPRY domain-containing SOCS box protein 3 {ECO:0000313|Ensembl:ENSP00000455098}; Flags: Fragment;+++[Q96LS6_HUMAN|Unreviewed]SubName: Full=SplA/ryanodine receptor domain and SOCS box containing 3, isoform CRA_c {ECO:0000313|EMBL:EAW85621.1}; SubName: Full=cDNA FLJ25121 fis, clone CBR06051 {ECO:0000313|EMBL:BAB71594.1};"]
[9096,"'TBX18'",67,73,70,null,"H01867///Congenital anomalies of kidney and urinary tract (CAKUT)",null,null,"GO:0005634///nucleus","GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0042803///protein homodimerization activity+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0046982///protein heterodimerization activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0072001///renal system development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060829///negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation+++GO:0007275///multicellular organism development","IPR008967///p53-like transcription factor, DNA-binding+++IPR036960///T-box superfamily+++IPR018186///Transcription factor, T-box, conserved site+++IPR001699///Transcription factor, T-box","[TBX18_HUMAN|Reviewed]RecName: Full=T-box transcription factor TBX18; Short=T-box protein 18;+++[Q8IW86_HUMAN|Unreviewed]SubName: Full=TBX18 protein {ECO:0000313|EMBL:AAH40697.2}; Flags: Fragment;+++[U3KQ31_HUMAN|Unreviewed]SubName: Full=T-box transcription factor TBX18 {ECO:0000313|Ensembl:ENSP00000475498}; Flags: Fragment;+++[U3KQH2_HUMAN|Unreviewed]SubName: Full=T-box transcription factor TBX18 {ECO:0000313|Ensembl:ENSP00000475873};+++[U3KQQ9_HUMAN|Unreviewed]SubName: Full=T-box transcription factor TBX18 {ECO:0000313|Ensembl:ENSP00000476137}; Flags: Fragment;"]
[91057,"'CCDC34'",138,70,104,{"$nulls":7},"IPR025259///Coiled-coil domain-containing protein 34","[CCD34_HUMAN|Reviewed]RecName: Full=Coiled-coil domain-containing protein 34; AltName: Full=Renal carcinoma antigen NY-REN-41;"]
[9117,"'SEC22C'",356,402.99,379.495,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0016192///vesicle-mediated transport+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0015031///protein transport","IPR011012///Longin-like domain superfamily+++IPR010908///Longin domain","[SC22C_HUMAN|Reviewed]RecName: Full=Vesicle-trafficking protein SEC22c; AltName: Full=SEC22 vesicle-trafficking protein homolog C; AltName: Full=SEC22 vesicle-trafficking protein-like 3;+++[A0A024R2N5_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein-like 3 (S. cerevisiae), isoform CRA_b {ECO:0000313|EMBL:EAW64656.1}; SubName: Full=SEC22 vesicle trafficking protein-like protein C isoform 1 {ECO:0000313|EMBL:ALQ33921.1};+++[A0A024R2Q1_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein-like 3 (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW64655.1};+++[A0A0S2Z4S0_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein-like protein C isoform 2 {ECO:0000313|EMBL:ALQ33922.1};+++[A0A0S2Z4S8_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein-like protein C isoform 3 {ECO:0000313|EMBL:ALQ33923.1};+++[C9J2R1_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000397170}; Flags: Fragment;+++[C9J448_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000391170}; Flags: Fragment;+++[C9J9A4_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000391957}; Flags: Fragment;+++[C9JNW1_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000408242}; Flags: Fragment;+++[F8VQT7_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000404987};+++[F8WBN1_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000411725};+++[F8WDR5_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000389589};+++[H7C479_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22c {ECO:0000313|Ensembl:ENSP00000415969}; Flags: Fragment;"]
[9128,"'PRPF4'",337,324,330.5,"03040///Spliceosome","H00527///Retinitis pigmentosa (RP)","M00354///Spliceosome, U4/U6.U5 tri-snRNP",null,"GO:0015030///Cajal body+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0071005///U2-type precatalytic spliceosome+++GO:0071001///U4/U6 snRNP+++GO:0005681///spliceosomal complex+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm+++GO:0097525///spliceosomal snRNP complex+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0017070///U6 snRNA binding+++GO:0030621///U4 snRNA binding","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing+++GO:0000375///RNA splicing, via transesterification reactions+++GO:0006396///RNA processing","IPR017986///WD40-repeat-containing domain+++IPR036285///PRP4-like superfamily+++IPR027106///U4/U6 small nuclear ribonucleoprotein Prp4+++IPR019775///WD40 repeat, conserved site+++IPR014906///Pre-mRNA processing factor 4 (PRP4)-like+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR001680///WD40 repeat+++IPR036322///WD40-repeat-containing domain superfamily+++IPR020472///G-protein beta WD-40 repeat","[PRP4_HUMAN|Reviewed]RecName: Full=U4/U6 small nuclear ribonucleoprotein Prp4; AltName: Full=PRP4 homolog; Short=hPrp4; AltName: Full=U4/U6 snRNP 60 kDa protein; AltName: Full=WD splicing factor Prp4;+++[Q5T1M7_HUMAN|Unreviewed]SubName: Full=60 kDa U4/U6 snRNP-specific spliceosomal protein {ECO:0000313|EMBL:AAS78572.1}; SubName: Full=PRP4 pre-mRNA processing factor 4 homolog (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW87363.1};+++[Q6IAP9_HUMAN|Unreviewed]SubName: Full=PRPF4 protein {ECO:0000313|EMBL:CAG33386.1};"]
[9136,"'RRP9'",184,116,150,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0032040///small-subunit processome+++GO:0005634///nucleus+++GO:0031428///box C/D snoRNP complex+++GO:0005730///nucleolus","GO:0030515///snoRNA binding+++GO:0034511///U3 snoRNA binding+++GO:0003723///RNA binding","GO:0006364///rRNA processing","IPR017986///WD40-repeat-containing domain+++IPR001680///WD40 repeat+++IPR020472///G-protein beta WD-40 repeat+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR036322///WD40-repeat-containing domain superfamily+++IPR019775///WD40 repeat, conserved site+++IPR039241///Ribosomal RNA-processing protein Rrp9-like","[U3IP2_HUMAN|Reviewed]RecName: Full=U3 small nucleolar RNA-interacting protein 2; AltName: Full=RRP9 homolog; AltName: Full=U3 small nucleolar ribonucleoprotein-associated 55 kDa protein; Short=U3 snoRNP-associated 55 kDa protein; Short=U3-55K;"]
[9144,"'SYNGR2'",4306,4257,4281.5,"00240///Pyrimidine metabolism+++00983///Drug metabolism - other enzymes+++01100///Metabolic pathways","H00469///Mitochondrial DNA depletion syndrome (MDS)+++H01118///Progressive external ophthalmoplegia (PEO)",null,"R08233///ATP:5-fluorodeoxyuridine 5'-phosphotransferase 5-Fluorodeoxyuridine + ATP <=> 5-Fluorodeoxyuridine monophosphate + ADP+++R01567///ATP:thymidine 5'-phosphotransferase ATP + Thymidine <=> ADP + dTMP+++R02099///ATP:deoxyuridine 5'-phosphotransferase ATP + Deoxyuridine <=> ADP + dUMP","GO:0030672///synaptic vesicle membrane+++GO:0030054///cell junction+++GO:0030659///cytoplasmic vesicle membrane+++GO:0070062///extracellular exosome+++GO:0016021///integral component of membrane+++GO:0008021///synaptic vesicle+++GO:0045202///synapse+++GO:0005811///lipid droplet+++GO:0031594///neuromuscular junction+++GO:0016020///membrane+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding","GO:0045055///regulated exocytosis+++GO:0048499///synaptic vesicle membrane organization","IPR016579///Synaptogyrin+++IPR008253///Marvel domain","[SNG2_HUMAN|Reviewed]RecName: Full=Synaptogyrin-2 {ECO:0000305}; AltName: Full=Cellugyrin {ECO:0000250|UniProtKB:O54980};+++[A0A024R8T9_HUMAN|Unreviewed]RecName: Full=Synaptogyrin {ECO:0000256|PIRNR:PIRNR011282};+++[K7EJ35_HUMAN|Unreviewed]SubName: Full=Synaptogyrin 2, isoform CRA_a {ECO:0000313|EMBL:EAW89499.1}; SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000465005};+++[K7ELD9_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000466032};+++[K7ELS8_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000466204}; Flags: Fragment;+++[K7ENG9_HUMAN|Unreviewed]SubName: Full=Synaptogyrin-2 {ECO:0000313|Ensembl:ENSP00000466942};"]
[9154,"'SLC28A1'",0,1,0.5,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0015389///pyrimidine- and adenine-specific:sodium symporter activity+++GO:0005415///nucleoside:sodium symporter activity+++GO:0005337///nucleoside transmembrane transporter activity","GO:0072531///pyrimidine-containing compound transmembrane transport+++GO:1901642///nucleoside transmembrane transport+++GO:1904823///purine nucleobase transmembrane transport+++GO:0015858///nucleoside transport+++GO:0015855///pyrimidine nucleobase transport+++GO:0006139///nucleobase-containing compound metabolic process","IPR008276///Concentrative nucleoside transporter+++IPR018270///Concentrative nucleoside transporter, metazoan/bacterial+++IPR030212///Concentrative nucleoside transporter CNT1/CNT2+++IPR011657///Concentrative nucleoside transporter C-terminal domain+++IPR011642///Nucleoside transporter/FeoB GTPase, Gate domain+++IPR002668///Concentrative nucleoside transporter N-terminal domain","[S28A1_HUMAN|Reviewed]RecName: Full=Sodium/nucleoside cotransporter 1; AltName: Full=Concentrative nucleoside transporter 1; Short=CNT 1; Short=hCNT1; AltName: Full=Na(+)/nucleoside cotransporter 1; AltName: Full=Sodium-coupled nucleoside transporter 1; AltName: Full=Solute carrier family 28 member 1;+++[B7Z3L5_HUMAN|Unreviewed]RecName: Full=Sodium/nucleoside cotransporter {ECO:0000256|RuleBase:RU362018};+++[B7Z3L6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58165, highly similar to Sodium/nucleoside cotransporter 1 {ECO:0000313|EMBL:BAH12252.1};+++[B7Z533_HUMAN|Unreviewed]RecName: Full=Sodium/nucleoside cotransporter {ECO:0000256|RuleBase:RU362018};"]
[91646,"'TDRD12'",5,3,4,{"$nulls":4},"GO:0005575///cellular_component+++GO:1990923///PET complex","GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0003676///nucleic acid binding+++GO:0003674///molecular_function+++GO:0004386///helicase activity","GO:0031047///gene silencing by RNA+++GO:0034587///piRNA metabolic process+++GO:0007140///male meiotic nuclear division+++GO:0007283///spermatogenesis+++GO:0043046///DNA methylation involved in gamete generation+++GO:0009566///fertilization+++GO:0051321///meiotic cell cycle+++GO:0030154///cell differentiation+++GO:0007275///multicellular organism development","IPR007052///CS domain+++IPR035437///SNase-like, OB-fold superfamily+++IPR011545///DEAD/DEAH box helicase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR008978///HSP20-like chaperone+++IPR002999///Tudor domain","[TDR12_HUMAN|Reviewed]RecName: Full=Putative ATP-dependent RNA helicase TDRD12; EC=3.6.4.13; AltName: Full=ES cell-associated transcript 8 protein; AltName: Full=Tudor domain-containing protein 12;+++[A0A1B0GU57_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000489971}; Flags: Fragment;+++[A0A1W2PRK2_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000492643}; Flags: Fragment;+++[A0A2R8Y872_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000496698};+++[H3BU70_HUMAN|Unreviewed]SubName: Full=Putative ATP-dependent RNA helicase TDRD12 {ECO:0000313|Ensembl:ENSP00000457498}; Flags: Fragment;"]
[9170,"'LPAR2'",130,143,136.5,"04072///Phospholipase D signaling pathway+++04810///Regulation of actin cytoskeleton+++04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway+++04080///Neuroactive ligand-receptor interaction+++05200///Pathways in cancer",{"$nulls":3},"GO:0030139///endocytic vesicle+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0009986///cell surface","GO:0070915///lysophosphatidic acid receptor activity+++GO:0005515///protein binding+++GO:0008289///lipid binding+++GO:0004930///G protein-coupled receptor activity","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0007165///signal transduction+++GO:0007202///activation of phospholipase C activity+++GO:0007204///positive regulation of cytosolic calcium ion concentration","IPR004065///Lysophosphatidic acid receptor+++IPR004066///Lysophosphatidic acid receptor EDG-4+++IPR000276///G protein-coupled receptor, rhodopsin-like+++IPR017452///GPCR, rhodopsin-like, 7TM","[LPAR2_HUMAN|Reviewed]RecName: Full=Lysophosphatidic acid receptor 2; Short=LPA receptor 2; Short=LPA-2; AltName: Full=Lysophosphatidic acid receptor Edg-4;+++[A0A024R7M9_HUMAN|Unreviewed]SubName: Full=Endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4, isoform CRA_a {ECO:0000313|EMBL:EAW84837.1};+++[K7EJJ9_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000465206}; Flags: Fragment;+++[K7ELJ6_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000466112}; Flags: Fragment;+++[K7ENG7_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000466940}; Flags: Fragment;+++[K7ER68_HUMAN|Unreviewed]SubName: Full=Lysophosphatidic acid receptor 2 {ECO:0000313|Ensembl:ENSP00000468132}; Flags: Fragment;+++[L8E990_HUMAN|Unreviewed]SubName: Full=Alternative protein LPAR2 {ECO:0000313|EMBL:CCQ43276.1};"]
[91801,"'ALKBH8'",23,53,38,{"$nulls":4},"GO:0005829///cytosol+++GO:0016604///nuclear body+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0016491///oxidoreductase activity+++GO:0005506///iron ion binding+++GO:0016740///transferase activity+++GO:0003824///catalytic activity+++GO:0016300///tRNA (uracil) methyltransferase activity+++GO:0016706///oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors+++GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0000049///tRNA binding+++GO:0008270///zinc ion binding+++GO:0008168///methyltransferase activity+++GO:0003676///nucleic acid binding","GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0055114///oxidation-reduction process+++GO:0006974///cellular response to DNA damage stimulus+++GO:0008152///metabolic process+++GO:0002098///tRNA wobble uridine modification","IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR034256///ALKBH8, RNA recognition motif+++IPR035979///RNA-binding domain superfamily+++IPR029063///S-adenosyl-L-methionine-dependent methyltransferase+++IPR005123///Oxoglutarate/iron-dependent dioxygenase+++IPR013216///Methyltransferase type 11+++IPR032863///Alkylated DNA repair protein alkB homologue 8+++IPR027450///Alpha-ketoglutarate-dependent dioxygenase AlkB-like+++IPR015095///Alkylated DNA repair protein AlkB, homologue 8, N-terminal","[ALKB8_HUMAN|Reviewed]RecName: Full=Alkylated DNA repair protein alkB homolog 8; EC=1.14.11.-; AltName: Full=Probable alpha-ketoglutarate-dependent dioxygenase ABH8; AltName: Full=S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8; AltName: Full=tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8; EC=2.1.1.229;+++[C9JQN2_HUMAN|Unreviewed]SubName: Full=Alkylated DNA repair protein alkB homolog 8 {ECO:0000313|Ensembl:ENSP00000376812};"]
[9189,"'ZBED1'",394.42,435.8,415.11,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0000228///nuclear chromosome+++GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0019789///SUMO transferase activity+++GO:0046872///metal ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0042802///identical protein binding+++GO:0046983///protein dimerization activity","GO:0016925///protein sumoylation+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR012337///Ribonuclease H-like superfamily+++IPR008906///HAT, C-terminal dimerisation domain+++IPR003656///Zinc finger, BED-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR037220///Zinc finger BED domain","[ZBED1_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 1; AltName: Full=Putative Ac-like transposable element; AltName: Full=dREF homolog;+++[A0A024RBU4_HUMAN|Unreviewed]SubName: Full=HCG1981838, isoform CRA_b {ECO:0000313|EMBL:EAW98692.1};+++[C9JXP4_HUMAN|Unreviewed]SubName: Full=Zinc finger BED domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000419148}; Flags: Fragment;"]
[9200,"'HACD1'",514,503,508.5,"01212///Fatty acid metabolism+++01040///Biosynthesis of unsaturated fatty acids+++01110///Biosynthesis of secondary metabolites+++00062///Fatty acid elongation",null,"M00415///Fatty acid biosynthesis, elongation, endoplasmic reticulum","R07760///3-Hydroxyoctadecanoyl-CoA <=> (2E)-Octadecenoyl-CoA + H2O+++R10827///very-long-chain (3R)-3-hydroxyacyl-CoA hydro-lyase   Very-long-chain (3R)-3-hydroxyacyl-CoA <=> Very-long-chain trans-2,3-dehydroacyl-CoA + H2O","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0102158///very-long-chain 3-hydroxyacyl-CoA dehydratase activity+++GO:0018812///3-hydroxyacyl-CoA dehydratase activity+++GO:0016829///lyase activity+++GO:0102343///3-hydroxy-arachidoyl-CoA dehydratase activity+++GO:0080023///3R-hydroxyacyl-CoA dehydratase activity+++GO:0102345///3-hydroxy-lignoceroyl-CoA dehydratase activity+++GO:0102344///3-hydroxy-behenoyl-CoA dehydratase activity+++GO:0046848///hydroxyapatite binding+++GO:0019899///enzyme binding","GO:0007275///multicellular organism development+++GO:0030497///fatty acid elongation+++GO:0006629///lipid metabolic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0006633///fatty acid biosynthetic process+++GO:0042761///very long-chain fatty acid biosynthetic process+++GO:0071529///cementum mineralization+++GO:0034622///cellular protein-containing complex assembly+++GO:0030148///sphingolipid biosynthetic process+++GO:0035338///long-chain fatty-acyl-CoA biosynthetic process+++GO:0006631///fatty acid metabolic process","IPR007482///Protein-tyrosine phosphatase-like, PTPLA","[HACD1_HUMAN|Reviewed]RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000305}; EC=4.2.1.134 {ECO:0000269|PubMed:18554506, ECO:0000269|PubMed:23933735}; AltName: Full=3-hydroxyacyl-CoA dehydratase 1 {ECO:0000303|PubMed:18554506}; Short=HACD1 {ECO:0000303|PubMed:15164054}; AltName: Full=Cementum-attachment protein {ECO:0000303|PubMed:22067203}; Short=CAP {ECO:0000303|PubMed:22067203}; AltName: Full=Protein-tyrosine phosphatase-like member A {ECO:0000312|HGNC:HGNC:9639};+++[A6NP58_HUMAN|Unreviewed]SubName: Full=Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 {ECO:0000313|Ensembl:ENSP00000322923};+++[B0YJ83_HUMAN|Unreviewed]SubName: Full=Protein tyrosine phosphatase-like, member A variant 4 {ECO:0000313|EMBL:ACA06058.1};+++[J3KS69_HUMAN|Unreviewed]RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000256|RuleBase:RU363109}; EC=4.2.1.134 {ECO:0000256|RuleBase:RU363109}; Flags: Fragment;+++[J3KT94_HUMAN|Unreviewed]RecName: Full=Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase {ECO:0000256|RuleBase:RU363109}; EC=4.2.1.134 {ECO:0000256|RuleBase:RU363109}; Flags: Fragment;"]
[9211,"'LGI1'",2.72,2,2.36,{"$nulls":4},"GO:0005615///extracellular space+++GO:0043083///synaptic cleft+++GO:0005576///extracellular region+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005102///signaling receptor binding","GO:0007399///nervous system development+++GO:0008283///cell proliferation+++GO:0050806///positive regulation of synaptic transmission+++GO:0051260///protein homooligomerization+++GO:0030307///positive regulation of cell growth+++GO:0031175///neuron projection development+++GO:0099645///neurotransmitter receptor localization to postsynaptic specialization membrane+++GO:0007411///axon guidance","IPR032675///Leucine-rich repeat domain superfamily+++IPR009039///EAR+++IPR001611///Leucine-rich repeat+++IPR003591///Leucine-rich repeat, typical subtype+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR005492///Leucine-rich glioma-inactivated , EPTP repeat","[LGI1_HUMAN|Reviewed]RecName: Full=Leucine-rich glioma-inactivated protein 1; AltName: Full=Epitempin-1; Flags: Precursor;+++[A0A0D9SFE3_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000486517};+++[A0A0D9SFH6_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000486607};+++[A0A0D9SFS5_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma inactivated 1 isoform 3 {ECO:0000313|EMBL:ALQ33927.1}; SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000486859};+++[A0A0D9SFU4_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000486908};+++[A0A0S2Z4S7_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma inactivated 1 isoform 1 {ECO:0000313|EMBL:ALQ33926.1}; Flags: Fragment;+++[A0A0S2Z4X3_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma inactivated 1 isoform 4 {ECO:0000313|EMBL:ALQ33928.1}; SubName: Full=Leucine-rich, glioma inactivated 1, isoform CRA_c {ECO:0000313|EMBL:EAW50053.1};+++[A0A0S2Z5G1_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma inactivated 1 isoform 5 {ECO:0000313|EMBL:ALQ33929.1};+++[A0A1B0GTM5_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000489763};+++[A0A1B0GUD3_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000490058};+++[A0A1B0GV33_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000490355};+++[A0A1B0GVF6_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000490496};+++[A0A1B0GVP2_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000490597};+++[A0A1B0GWB4_HUMAN|Unreviewed]SubName: Full=Leucine-rich glioma-inactivated protein 1 {ECO:0000313|Ensembl:ENSP00000490860};"]
[922,"'CD5L'",1,0,0.5,{"$nulls":4},"GO:0072562///blood microparticle+++GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0005044///scavenger receptor activity","GO:0006968///cellular defense response+++GO:0002376///immune system process+++GO:0006915///apoptotic process+++GO:0006898///receptor-mediated endocytosis+++GO:0006954///inflammatory response","IPR001190///SRCR domain+++IPR017448///SRCR-like domain+++IPR036772///SRCR-like domain superfamily","[CD5L_HUMAN|Reviewed]RecName: Full=CD5 antigen-like; AltName: Full=Apoptosis inhibitor expressed by macrophages {ECO:0000303|PubMed:23236605}; Short=hAIM {ECO:0000303|PubMed:23236605}; AltName: Full=CT-2 {ECO:0000303|Ref.2}; AltName: Full=IgM-associated peptide {ECO:0000303|PubMed:8034987}; AltName: Full=SP-alpha {ECO:0000303|PubMed:9045627}; Flags: Precursor;"]
[9230,"'RAB11B'",4554,3624,4089,"04152///AMPK signaling pathway+++04962///Vasopressin-regulated water reabsorption+++04144///Endocytosis",{"$nulls":3},"GO:0055037///recycling endosome+++GO:0055038///recycling endosome membrane+++GO:0008021///synaptic vesicle+++GO:0030670///phagocytic vesicle membrane+++GO:0045335///phagocytic vesicle+++GO:0030054///cell junction+++GO:0098993///anchored component of synaptic vesicle membrane+++GO:0031410///cytoplasmic vesicle","GO:0005525///GTP binding+++GO:0019003///GDP binding+++GO:0003924///GTPase activity+++GO:0031489///myosin V binding","GO:0001881///receptor recycling+++GO:0044070///regulation of anion transport+++GO:0032402///melanosome transport+++GO:2001135///regulation of endocytic recycling+++GO:0045055///regulated exocytosis+++GO:0045056///transcytosis+++GO:0090150///establishment of protein localization to membrane+++GO:2000008///regulation of protein localization to cell surface+++GO:0045054///constitutive secretory pathway+++GO:0071468///cellular response to acidic pH+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0033572///transferrin transport+++GO:0035773///insulin secretion involved in cellular response to glucose stimulus","IPR001806///Small GTPase+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR005225///Small GTP-binding protein domain","[RB11B_HUMAN|Reviewed]RecName: Full=Ras-related protein Rab-11B; AltName: Full=GTP-binding protein YPT3; Flags: Precursor;"]
[9238,"'TBRG4'",811,733,772,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005739///mitochondrion+++GO:0005759///mitochondrial matrix","GO:0003723///RNA binding+++GO:0004672///protein kinase activity+++GO:0005515///protein binding","GO:0045333///cellular respiration+++GO:0007050///cell cycle arrest+++GO:0044528///regulation of mitochondrial mRNA stability+++GO:0090615///mitochondrial mRNA processing+++GO:0016071///mRNA metabolic process+++GO:0008284///positive regulation of cell proliferation+++GO:0006468///protein phosphorylation","IPR013579///FAST kinase-like protein, subdomain 2+++IPR013584///RAP domain+++IPR010622///FAST kinase leucine-rich","[FAKD4_HUMAN|Reviewed]RecName: Full=FAST kinase domain-containing protein 4 {ECO:0000303|PubMed:20869947}; AltName: Full=Cell cycle progression restoration protein 2; Short=Cell cycle progression protein 2; AltName: Full=Protein TBRG4; AltName: Full=Transforming growth factor beta regulator 4 {ECO:0000312|HGNC:HGNC:17443}; Flags: Precursor;+++[B3KM73_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10419 fis, clone NT2RP1000163, highly similar to Homo sapiens transforming growth factor beta regulator 4 (TBRG4), transcript variant 3, mRNA {ECO:0000313|EMBL:BAG50885.1};+++[B3KRS4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ34813 fis, clone NT2NE2007725, highly similar to Homo sapiens transforming growth factor beta regulator 4 (TBRG4), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG52486.1}; SubName: Full=cDNA FLJ61734, highly similar to Homo sapiens transforming growth factor beta regulator 4 (TBRG4), transcript variant 1, mRNA {ECO:0000313|EMBL:BAH12734.1};+++[B4DU42_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56153, highly similar to Homo sapiens transforming growth factor beta regulator 4 (TBRG4), transcript variant 1, mRNA {ECO:0000313|EMBL:BAG62204.1};+++[C9IZN7_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000418631}; Flags: Fragment;+++[C9J347_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000417324}; Flags: Fragment;+++[C9J5A2_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000417967}; Flags: Fragment;+++[C9J618_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000417071}; Flags: Fragment;+++[C9J7P5_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000417743}; Flags: Fragment;+++[D3DVL7_HUMAN|Unreviewed]SubName: Full=Transforming growth factor beta regulator 4, isoform CRA_b {ECO:0000313|EMBL:EAW61056.1};+++[H7C4R5_HUMAN|Unreviewed]SubName: Full=FAST kinase domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000417974}; Flags: Fragment;"]
[92521,"'SPECC1'",2941.59,3336,3138.795,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0031941///filamentous actin+++GO:0016020///membrane+++GO:0005815///microtubule organizing center","GO:0042802///identical protein binding+++GO:0043621///protein self-association+++GO:0097602///cullin family protein binding","GO:0030036///actin cytoskeleton organization","IPR036872///CH domain superfamily+++IPR001715///Calponin homology domain","[CYTSB_HUMAN|Reviewed]RecName: Full=Cytospin-B; AltName: Full=Nuclear structure protein 5; Short=NSP5; AltName: Full=Sperm antigen HCMOGT-1; AltName: Full=Sperm antigen with calponin homology and coiled-coil domains 1;+++[A0A024QYY9_HUMAN|Unreviewed]SubName: Full=Spectrin domain with coiled-coils 1, isoform CRA_a {ECO:0000313|EMBL:EAW50917.1};+++[B4DW07_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50032, highly similar to Homo sapiens spectrin domain with coiled-coils 1 (SPECC1), transcript variant, mRNA {ECO:0000313|EMBL:BAG62869.1};+++[B4E2A4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ53275, highly similar to Homo sapiens spectrin domain with coiled-coils 1 (SPECC1), transcript variant, mRNA {ECO:0000313|EMBL:BAG65066.1};+++[J3KRB9_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000461918}; Flags: Fragment;+++[J3KRD8_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000461944}; Flags: Fragment;+++[J3KRN9_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000462092}; Flags: Fragment;+++[J3KS18_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000462266}; Flags: Fragment;+++[J3KSG2_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000462471}; Flags: Fragment;+++[J3KTH6_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000462987}; Flags: Fragment;+++[J3KTI9_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000463006}; Flags: Fragment;+++[J3QKL1_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000463130};+++[J3QQM0_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000463799};+++[J3QRQ9_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000464341}; Flags: Fragment;+++[J3QS22_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000464489}; Flags: Fragment;+++[J3QSD6_HUMAN|Unreviewed]SubName: Full=Cytospin-B {ECO:0000313|Ensembl:ENSP00000464639}; Flags: Fragment;"]
[9262,"'STK17B'",53.98,70.93,62.455,{"$nulls":4},"GO:0015629///actin cytoskeleton+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0005886///plasma membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment","GO:0004672///protein kinase activity+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity","GO:0035556///intracellular signal transduction+++GO:2000271///positive regulation of fibroblast apoptotic process+++GO:0016310///phosphorylation+++GO:0046777///protein autophosphorylation+++GO:0012501///programmed cell death+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process","IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR008271///Serine/threonine-protein kinase, active site","[ST17B_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase 17B; EC=2.7.11.1; AltName: Full=DAP kinase-related apoptosis-inducing protein kinase 2;+++[C9JZJ1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 17B {ECO:0000313|Ensembl:ENSP00000399755}; Flags: Fragment;+++[Q53QE7_HUMAN|Unreviewed]SubName: Full=Serine/threonine kinase 17b (Apoptosis-inducing) {ECO:0000313|EMBL:EAW70122.1}; SubName: Full=cDNA, FLJ93309, Homo sapiens serine/threonine kinase 17b (apoptosis-inducing) (STK17B), mRNA {ECO:0000313|EMBL:BAG35717.1};+++[Q6FG83_HUMAN|Unreviewed]SubName: Full=STK17B protein {ECO:0000313|EMBL:CAG47021.1}; Flags: Fragment;+++[Q6FG98_HUMAN|Unreviewed]SubName: Full=STK17B protein {ECO:0000313|EMBL:CAG47006.1};+++[U3KQF8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase 17B {ECO:0000313|Ensembl:ENSP00000475843}; Flags: Fragment;"]
[9274,"'BCL7C'",1236,792,1014,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0035861///site of double-strand break","GO:0042803///protein homodimerization activity+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0046975///histone methyltransferase activity (H3-K36 specific)+++GO:0044547///DNA topoisomerase binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008270///zinc ion binding","GO:0006915///apoptotic process","IPR006804///BCL7","[BCL7C_HUMAN|Reviewed]RecName: Full=B-cell CLL/lymphoma 7 protein family member C;+++[I3L1Q2_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member C {ECO:0000313|Ensembl:ENSP00000459007}; Flags: Fragment;+++[I3L4D5_HUMAN|Unreviewed]SubName: Full=B-cell CLL/lymphoma 7 protein family member C {ECO:0000313|Ensembl:ENSP00000461177};"]
[92840,"'REEP6'",396,357,376.5,{"$nulls":4},"GO:0005789///endoplasmic reticulum membrane+++GO:0045177///apical part of cell+++GO:0005783///endoplasmic reticulum+++GO:0001917///photoreceptor inner segment+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0044317///rod spherule+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0050908///detection of light stimulus involved in visual perception+++GO:0032386///regulation of intracellular transport","IPR004345///TB2/DP1/HVA22-related protein","[REEP6_HUMAN|Reviewed]RecName: Full=Receptor expression-enhancing protein 6; AltName: Full=Polyposis locus protein 1-like 1;+++[A0A1L5BXV2_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006};+++[A8MWX0_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006}; Flags: Fragment;+++[A8MXN1_HUMAN|Unreviewed]RecName: Full=Receptor expression-enhancing protein {ECO:0000256|RuleBase:RU362006}; Flags: Fragment;"]
[93010,"'B3GNT7'",170,146,158,"00533///Glycosaminoglycan biosynthesis - keratan sulfate",null,null,"R07616///UDP-N-acetyl-D-galactosamine + G01941 <=> UDP + G13025+++R07615///UDP-N-acetyl-D-galactosamine + G01977 <=> UDP + G13024","GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0000139///Golgi membrane","GO:0008499///UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity+++GO:0008376///acetylgalactosaminyltransferase activity+++GO:0016740///transferase activity+++GO:0016757///transferase activity, transferring glycosyl groups+++GO:0008532///N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity+++GO:0008378///galactosyltransferase activity","GO:0018146///keratan sulfate biosynthetic process+++GO:0006486///protein glycosylation+++GO:0030311///poly-N-acetyllactosamine biosynthetic process+++GO:0016266///O-glycan processing","IPR002659///Glycosyl transferase, family 31","[B3GN7_HUMAN|Reviewed]RecName: Full=UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7; Short=BGnT-7; Short=Beta-1,3-Gn-T7; Short=Beta-1,3-N-acetylglucosaminyltransferase 7; Short=Beta3Gn-T7; EC=2.4.1.-;"]
[9314,"'KLF4'",98,129,113.5,"04550///Signaling pathways regulating pluripotency of stem cells","H01556///Meningioma",null,null,"GO:0005634///nucleus+++GO:0000790///nuclear chromatin+++GO:0005667///transcription factor complex+++GO:0000785///chromatin+++GO:0005654///nucleoplasm+++GO:0005719///nuclear euchromatin+++GO:0005737///cytoplasm+++GO:0044798///nuclear transcription factor complex","GO:0003690///double-stranded DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:1990841///promoter-specific chromatin binding+++GO:0046872///metal ion binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0035014///phosphatidylinositol 3-kinase regulator activity+++GO:0001010///RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity+++GO:0001221///transcription cofactor binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0043565///sequence-specific DNA binding+++GO:0008013///beta-catenin binding+++GO:0001085///RNA polymerase II transcription factor binding+++GO:0008134///transcription factor binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0042826///histone deacetylase binding+++GO:0008270///zinc ion binding","GO:0019827///stem cell population maintenance+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0030154///cell differentiation+++GO:0070373///negative regulation of ERK1 and ERK2 cascade+++GO:0030336///negative regulation of cell migration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0032088///negative regulation of NF-kappaB transcription factor activity+++GO:0043551///regulation of phosphatidylinositol 3-kinase activity+++GO:0090051///negative regulation of cell migration involved in sprouting angiogenesis+++GO:0048679///regulation of axon regeneration+++GO:0034115///negative regulation of heterotypic cell-cell adhesion+++GO:0045595///regulation of cell differentiation+++GO:0045415///negative regulation of interleukin-8 biosynthetic process+++GO:0008285///negative regulation of cell proliferation+++GO:0007500///mesodermal cell fate determination+++GO:0071409///cellular response to cycloheximide+++GO:0010629///negative regulation of gene expression+++GO:0060761///negative regulation of response to cytokine stimulus+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0048730///epidermis morphogenesis+++GO:0032270///positive regulation of cellular protein metabolic process+++GO:1904998///negative regulation of leukocyte adhesion to arterial endothelial cell+++GO:0071300///cellular response to retinoic acid+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0032526///response to retinoic acid+++GO:0016525///negative regulation of angiogenesis+++GO:2000342///negative regulation of chemokine (C-X-C motif) ligand 2 production+++GO:0014740///negative regulation of muscle hyperplasia+++GO:0045444///fat cell differentiation+++GO:0061614///pri-miRNA transcription by RNA polymerase II+++GO:0006366///transcription by RNA polymerase II+++GO:0010033///response to organic substance+++GO:0014067///negative regulation of phosphatidylinositol 3-kinase signaling+++GO:0071363///cellular response to growth factor stimulus+++GO:1901653///cellular response to peptide+++GO:0031077///post-embryonic camera-type eye development+++GO:0051898///negative regulation of protein kinase B signaling+++GO:0009913///epidermal cell differentiation+++GO:0050728///negative regulation of inflammatory response+++GO:0046985///positive regulation of hemoglobin biosynthetic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006351///transcription, DNA-templated+++GO:0035166///post-embryonic hemopoiesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:2000134///negative regulation of G1/S transition of mitotic cell cycle+++GO:1904798///positive regulation of core promoter binding+++GO:0043154///negative regulation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0071499///cellular response to laminar fluid shear stress+++GO:0070301///cellular response to hydrogen peroxide+++GO:0071407///cellular response to organic cyclic compound+++GO:0035019///somatic stem cell population maintenance+++GO:0042127///regulation of cell proliferation+++GO:0051973///positive regulation of telomerase activity+++GO:0010628///positive regulation of gene expression+++GO:1903672///positive regulation of sprouting angiogenesis+++GO:0051247///positive regulation of protein metabolic process+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0060070///canonical Wnt signaling pathway","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[KLF4_HUMAN|Reviewed]RecName: Full=Krueppel-like factor 4; AltName: Full=Epithelial zinc finger protein EZF; AltName: Full=Gut-enriched krueppel-like factor;+++[A0A087X0S4_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 4 {ECO:0000313|Ensembl:ENSP00000483629};+++[B7ZBT2_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 4 {ECO:0000313|Ensembl:ENSP00000404922}; Flags: Fragment;+++[F2VTX5_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 4 short isoform {ECO:0000313|EMBL:ADL14248.1};+++[L0R3V2_HUMAN|Unreviewed]SubName: Full=Kruppel-like factor 4 (Gut) {ECO:0000313|EMBL:CCO02799.1};+++[Q5T3J6_HUMAN|Unreviewed]SubName: Full=Krueppel-like factor 4 {ECO:0000313|Ensembl:ENSP00000399921}; Flags: Fragment;"]
[9325,"'TRIP4'",265,212,238.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0005815///microtubule organizing center+++GO:0016604///nuclear body+++GO:0005654///nucleoplasm+++GO:0031594///neuromuscular junction+++GO:0005737///cytoplasm+++GO:0099053///activating signal cointegrator 1 complex+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005856///cytoskeleton","GO:0019901///protein kinase binding+++GO:0030331///estrogen receptor binding+++GO:0044389///ubiquitin-like protein ligase binding+++GO:0046872///metal ion binding+++GO:0002020///protease binding+++GO:0003713///transcription coactivator activity+++GO:0016922///nuclear receptor binding+++GO:0008270///zinc ion binding+++GO:0035035///histone acetyltransferase binding+++GO:0005515///protein binding","GO:0045661///regulation of myoblast differentiation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030520///intracellular estrogen receptor signaling pathway+++GO:1901998///toxin transport","IPR039128///Activating signal cointegrator 1-like+++IPR015947///PUA-like superfamily+++IPR009349///Zinc finger, C2HC5-type+++IPR007374///ASCH domain","[TRIP4_HUMAN|Reviewed]RecName: Full=Activating signal cointegrator 1 {ECO:0000303|PubMed:10454579}; Short=ASC-1 {ECO:0000303|PubMed:10454579}; AltName: Full=Thyroid receptor-interacting protein 4 {ECO:0000303|PubMed:7776974}; Short=TR-interacting protein 4 {ECO:0000303|PubMed:7776974}; Short=TRIP-4 {ECO:0000303|PubMed:7776974};+++[H0YK63_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 {ECO:0000313|Ensembl:ENSP00000452675};+++[H0YKD9_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 {ECO:0000313|Ensembl:ENSP00000452764}; Flags: Fragment;+++[H0YL91_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 {ECO:0000313|Ensembl:ENSP00000453106};+++[H0YLN7_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 {ECO:0000313|Ensembl:ENSP00000453276};+++[H3BMU9_HUMAN|Unreviewed]SubName: Full=Activating signal cointegrator 1 {ECO:0000313|Ensembl:ENSP00000454558}; Flags: Fragment;"]
[9340,"'GLP2R'",4,4,4,"04080///Neuroactive ligand-receptor interaction",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0008528///G protein-coupled peptide receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0004967///glucagon receptor activity+++GO:0017046///peptide hormone binding","GO:0007186///G protein-coupled receptor signaling pathway+++GO:0071377///cellular response to glucagon stimulus+++GO:0007165///signal transduction+++GO:0007166///cell surface receptor signaling pathway+++GO:0007188///adenylate cyclase-modulating G protein-coupled receptor signaling pathway+++GO:0008284///positive regulation of cell proliferation","IPR001879///GPCR, family 2, extracellular hormone receptor domain+++IPR036445///GPCR family 2, extracellular hormone receptor domain superfamily+++IPR017981///GPCR, family 2-like+++IPR039125///GPCR family 2, glucagon-like peptide 2 receptor+++IPR017983///GPCR, family 2, secretin-like, conserved site+++IPR000832///GPCR, family 2, secretin-like","[GLP2R_HUMAN|Reviewed]RecName: Full=Glucagon-like peptide 2 receptor; Short=GLP-2 receptor; Short=GLP-2-R; Short=GLP-2R;+++[B2RAN4_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ95022, highly similar to Homo sapiens glucagon-like peptide 2 receptor (GLP2R), mRNA {ECO:0000313|EMBL:BAG36931.1};+++[E9PC86_HUMAN|Unreviewed]SubName: Full=Glucagon-like peptide 2 receptor {ECO:0000313|Ensembl:ENSP00000303605}; Flags: Fragment;+++[H0Y6C2_HUMAN|Unreviewed]SubName: Full=Glucagon-like peptide 2 receptor {ECO:0000313|Ensembl:ENSP00000404471};+++[I3L0P5_HUMAN|Unreviewed]SubName: Full=Glucagon-like peptide 2 receptor {ECO:0000313|Ensembl:ENSP00000458242};+++[Q4VAT1_HUMAN|Unreviewed]SubName: Full=GLP2R protein {ECO:0000313|EMBL:AAH96264.1}; Flags: Fragment;+++[Q4VAT2_HUMAN|Unreviewed]SubName: Full=GLP2R protein {ECO:0000313|EMBL:AAH96263.1}; Flags: Fragment;+++[Q4VAT4_HUMAN|Unreviewed]SubName: Full=GLP2R protein {ECO:0000313|EMBL:AAH96261.1}; Flags: Fragment;+++[Q86XI5_HUMAN|Unreviewed]SubName: Full=GLP2R protein {ECO:0000313|EMBL:AAH43390.1}; Flags: Fragment;"]
[9355,"'LHX2'",2447,2325,2386,{"$nulls":4},"GO:0005634///nucleus","GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003682///chromatin binding","GO:0021978///telencephalon regionalization+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001942///hair follicle development+++GO:0009953///dorsal/ventral pattern formation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:0022008///neurogenesis+++GO:0060041///retina development in camera-type eye+++GO:0021537///telencephalon development+++GO:0007411///axon guidance+++GO:0007498///mesoderm development+++GO:2000678///negative regulation of transcription regulatory region DNA binding+++GO:0048646///anatomical structure formation involved in morphogenesis+++GO:0050768///negative regulation of neurogenesis+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007420///brain development+++GO:0001843///neural tube closure+++GO:0007399///nervous system development+++GO:0021987///cerebral cortex development+++GO:0048675///axon extension+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0021772///olfactory bulb development+++GO:2000179///positive regulation of neural precursor cell proliferation+++GO:0030182///neuron differentiation+++GO:0045814///negative regulation of gene expression, epigenetic","IPR001356///Homeobox domain+++IPR017970///Homeobox, conserved site+++IPR009057///Homeobox-like domain superfamily+++IPR001781///Zinc finger, LIM-type","[LHX2_HUMAN|Reviewed]RecName: Full=LIM/homeobox protein Lhx2; Short=Homeobox protein LH-2; Short=LIM homeobox protein 2;+++[B3KNJ5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ14691 fis, clone NT2RP2005325, highly similar to LIM/homeobox protein Lhx2 {ECO:0000313|EMBL:BAG51357.1};+++[H0YM35_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000453448}; Flags: Fragment;+++[H7C0H1_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000394978}; Flags: Fragment;+++[U3KQT5_HUMAN|Unreviewed]SubName: Full=LIM/homeobox protein Lhx2 {ECO:0000313|Ensembl:ENSP00000476200}; Flags: Fragment;"]
[93659,"'CGB5'",15.29,41.05,28.17,{"$nulls":4},"GO:0005576///extracellular region","GO:0005179///hormone activity","GO:0016486///peptide hormone processing+++GO:0007292///female gamete generation+++GO:0007267///cell-cell signaling+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0007165///signal transduction+++GO:0006915///apoptotic process","IPR001545///Gonadotropin, beta subunit+++IPR029034///Cystine-knot cytokine+++IPR006208///Glycoprotein hormone subunit beta+++IPR018245///Gonadotropin, beta subunit, conserved site","[CGB3_HUMAN|Reviewed]RecName: Full=Choriogonadotropin subunit beta 3; AltName: Full=Choriogonadotropin subunit beta; Short=CG-beta; AltName: Full=Chorionic gonadotropin chain beta; Flags: Precursor;+++[A0A0F7RQP8_HUMAN|Unreviewed]SubName: Full=Chorionic gonadotropin beta subunit 3 {ECO:0000313|EMBL:CCP37873.1}; SubName: Full=Chorionic gonadotropin beta subunit 4 {ECO:0000313|EMBL:CCP37874.1};"]
[9379,"'NRXN2'",0,1,0.5,"04514///Cell adhesion molecules (CAMs)","H00756///Pitt-Hopkins syndrome",null,null,"GO:0005886///plasma membrane+++GO:0098793///presynapse+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0097109///neuroligin family protein binding+++GO:0050839///cell adhesion molecule binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005246///calcium channel regulator activity","GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:0071625///vocalization behavior+++GO:0097104///postsynaptic membrane assembly+++GO:0007165///signal transduction+++GO:0097119///postsynaptic density protein 95 clustering+++GO:0035176///social behavior+++GO:0007158///neuron cell-cell adhesion+++GO:0007269///neurotransmitter secretion+++GO:0007268///chemical synaptic transmission+++GO:0007155///cell adhesion+++GO:0042297///vocal learning+++GO:0030534///adult behavior+++GO:0007416///synapse assembly+++GO:0097116///gephyrin clustering involved in postsynaptic density assembly","IPR000742///EGF-like domain+++IPR001791///Laminin G domain+++IPR003585///Neurexin/syndecan/glycophorin C+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR027789///Syndecan/Neurexin domain+++IPR037440///Neurexin","[NRX2A_HUMAN|Reviewed]RecName: Full=Neurexin-2; AltName: Full=Neurexin II-alpha; AltName: Full=Neurexin-2-alpha; Flags: Precursor;+++[NRX2B_HUMAN|Reviewed]RecName: Full=Neurexin-2-beta; AltName: Full=Neurexin II-beta; Flags: Precursor;+++[G5E9G7_HUMAN|Unreviewed]SubName: Full=Neurexin 2, isoform CRA_a {ECO:0000313|EMBL:EAW74277.1}; SubName: Full=Neurexin-2 {ECO:0000313|Ensembl:ENSP00000386416};+++[H7BZC7_HUMAN|Unreviewed]SubName: Full=Neurexin-2 {ECO:0000313|Ensembl:ENSP00000388971}; Flags: Fragment;+++[H7C2R8_HUMAN|Unreviewed]SubName: Full=Neurexin-2 {ECO:0000313|Ensembl:ENSP00000407374}; Flags: Fragment;+++[H7C3D6_HUMAN|Unreviewed]SubName: Full=Neurexin-2 {ECO:0000313|Ensembl:ENSP00000411271}; Flags: Fragment;+++[H7C3J4_HUMAN|Unreviewed]SubName: Full=Neurexin-2 {ECO:0000313|Ensembl:ENSP00000412211}; Flags: Fragment;"]
[93979,"'CPA5'",13,6,9.5,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space","GO:0008237///metallopeptidase activity+++GO:0004180///carboxypeptidase activity+++GO:0004181///metallocarboxypeptidase activity+++GO:0008270///zinc ion binding+++GO:0016787///hydrolase activity+++GO:0046872///metal ion binding+++GO:0008233///peptidase activity","GO:0006508///proteolysis","IPR003146///Carboxypeptidase, activation peptide+++IPR036990///Metallocarboxypeptidase-like, propeptide+++IPR000834///Peptidase M14, carboxypeptidase A","[CBPA5_HUMAN|Reviewed]RecName: Full=Carboxypeptidase A5; EC=3.4.17.-; Flags: Precursor;+++[A0A1D5RMQ7_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000419013}; Flags: Fragment;+++[A4D1M2_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|EMBL:EAL24090.1}; SubName: Full=Carboxypeptidase A5, isoform CRA_a {ECO:0000313|EMBL:EAW83754.1}; SubName: Full=Testicular tissue protein Li 32 {ECO:0000313|EMBL:AEE60945.1};+++[B2RCS8_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ96260, highly similar to Homo sapiens carboxypeptidase A5 (CPA5), mRNA {ECO:0000313|EMBL:BAG37675.1};+++[C9JRV5_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000420060}; Flags: Fragment;+++[C9JZE9_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000419778}; Flags: Fragment;+++[H7C4Q6_HUMAN|Unreviewed]SubName: Full=Carboxypeptidase A5 {ECO:0000313|Ensembl:ENSP00000417886}; Flags: Fragment;"]
[9398,"'CD101'",3.32,4,3.66,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane","GO:0016812///hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides","GO:0002763///positive regulation of myeloid leukocyte differentiation+++GO:0007166///cell surface receptor signaling pathway","IPR013106///Immunoglobulin V-set domain+++IPR003599///Immunoglobulin subtype+++IPR002195///Dihydroorotase, conserved site+++IPR007110///Immunoglobulin-like domain+++IPR013098///Immunoglobulin I-set+++IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily","[IGSF2_HUMAN|Reviewed]RecName: Full=Immunoglobulin superfamily member 2; Short=IgSF2; AltName: Full=Cell surface glycoprotein V7; AltName: Full=Glu-Trp-Ile EWI motif-containing protein 101; Short=EWI-101; AltName: CD_antigen=CD101; Flags: Precursor;+++[A0A1L7MZP9_HUMAN|Unreviewed]SubName: Full=CD101 molecule {ECO:0000313|EMBL:BAW18709.1}; Flags: Fragment;+++[A0A1L7MZR3_HUMAN|Unreviewed]SubName: Full=CD101 molecule {ECO:0000313|EMBL:BAW18707.1}; Flags: Fragment;+++[A0A1L7MZY4_HUMAN|Unreviewed]SubName: Full=CD101 molecule {ECO:0000313|EMBL:BAW18708.1}; Flags: Fragment;"]
[94039,"'ZNF101'",69.8,57.83,63.815,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR001909///Krueppel-associated box+++IPR036051///KRAB domain superfamily+++IPR036236///Zinc finger C2H2 superfamily","[ZN101_HUMAN|Reviewed]RecName: Full=Zinc finger protein 101; AltName: Full=Zinc finger protein HZF12;+++[K7EN16_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 101 {ECO:0000313|Ensembl:ENSP00000466744}; Flags: Fragment;+++[K7ENV8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 101 {ECO:0000313|Ensembl:ENSP00000467112}; Flags: Fragment;+++[Q504T0_HUMAN|Unreviewed]SubName: Full=ZNF101 protein {ECO:0000313|EMBL:AAH94808.1}; SubName: Full=Zinc finger protein 101 {ECO:0000313|Ensembl:ENSP00000466697};+++[Q96F93_HUMAN|Unreviewed]SubName: Full=ZNF101 protein {ECO:0000313|EMBL:AAH11502.2}; Flags: Fragment;"]
[9412,"'MED21'",166,167,166.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0016592///mediator complex+++GO:0000151///ubiquitin ligase complex","GO:0061630///ubiquitin protein ligase activity+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity+++GO:0005515///protein binding+++GO:0003713///transcription coactivator activity","GO:0016567///protein ubiquitination+++GO:0019827///stem cell population maintenance+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0001824///blastocyst development+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0032774///RNA biosynthetic process","IPR021384///Mediator complex, subunit Med21+++IPR037212///Mediator complex, subunit Med7/Med21-like","[MED21_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 21; AltName: Full=Mediator complex subunit 21; AltName: Full=RNA polymerase II holoenzyme component SRB7; Short=RNAPII complex component SRB7; Short=hSrb7;+++[A0A024RAW0_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit 21 isoform 1 {ECO:0000313|EMBL:ALQ33932.1}; SubName: Full=SRB7 suppressor of RNA polymerase B homolog (Yeast), isoform CRA_b {ECO:0000313|EMBL:EAW96547.1};+++[A0A0S2Z545_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit 21 isoform 2 {ECO:0000313|EMBL:ALQ33933.1};+++[F5GZQ1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 21 {ECO:0000313|Ensembl:ENSP00000444297};+++[F5H872_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 21 {ECO:0000313|Ensembl:ENSP00000442126};"]
[94239,"'H2AFV'",459.99,435,447.495,"04217///Necroptosis+++05322///Systemic lupus erythematosus+++05034///Alcoholism",{"$nulls":3},"GO:0000790///nuclear chromatin+++GO:0070062///extracellular exosome+++GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0000786///nucleosome","GO:0003677///DNA binding+++GO:0003674///molecular_function+++GO:0046982///protein heterodimerization activity","GO:0008150///biological_process+++GO:0006325///chromatin organization","IPR002119///Histone H2A+++IPR032458///Histone H2A conserved site+++IPR007125///Histone H2A/H2B/H3+++IPR032454///Histone H2A, C-terminal domain+++IPR009072///Histone-fold","[H2AV_HUMAN|Reviewed]RecName: Full=Histone H2A.V; AltName: Full=H2A.F/Z;+++[C9J0D1_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};+++[C9J386_HUMAN|Unreviewed]RecName: Full=Histone H2A {ECO:0000256|RuleBase:RU003767};+++[E5RJU1_HUMAN|Unreviewed]SubName: Full=Histone H2A.V {ECO:0000313|Ensembl:ENSP00000430492};"]
[9444,"'QKI'",860,1184,1022,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0017124///SH3 domain binding+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0006397///mRNA processing+++GO:0030154///cell differentiation+++GO:0007275///multicellular organism development+++GO:0008380///RNA splicing+++GO:0006417///regulation of translation+++GO:0051028///mRNA transport","IPR036612///K Homology domain, type 1 superfamily+++IPR032377///STAR protein, homodimerisation region+++IPR004087///K Homology domain+++IPR004088///K Homology domain, type 1+++IPR032367///Protein quaking, putative nuclear localisation signal","[QKI_HUMAN|Reviewed]RecName: Full=Protein quaking; Short=Hqk; Short=HqkI;+++[F5GXS8_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000440991}; Flags: Fragment;+++[F5GYM3_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000440599}; Flags: Fragment;+++[F5GYT7_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000441252};+++[F5H5U6_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000443106}; Flags: Fragment;+++[F5H8C8_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000443690}; Flags: Fragment;+++[H0YFB7_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000437867}; Flags: Fragment;+++[H0YG47_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000441773}; Flags: Fragment;+++[H0YGD6_HUMAN|Unreviewed]SubName: Full=Protein quaking {ECO:0000313|Ensembl:ENSP00000442848}; Flags: Fragment;+++[Q8WY44_HUMAN|Unreviewed]SubName: Full=Quaking protein 3 {ECO:0000313|EMBL:AAL36980.1}; Flags: Fragment;"]
[9466,"'IL27RA'",18,11,14.5,"04060///Cytokine-cytokine receptor interaction+++04630///Jak-STAT signaling pathway+++04659///Th17 cell differentiation",{"$nulls":3},"GO:0009897///external side of plasma membrane+++GO:0043235///receptor complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0019955///cytokine binding+++GO:0045509///interleukin-27 receptor activity+++GO:0004888///transmembrane signaling receptor activity+++GO:0004896///cytokine receptor activity","GO:0070106///interleukin-27-mediated signaling pathway+++GO:0002827///positive regulation of T-helper 1 type immune response+++GO:0048302///regulation of isotype switching to IgG isotypes+++GO:0070757///interleukin-35-mediated signaling pathway+++GO:0032729///positive regulation of interferon-gamma production+++GO:0002829///negative regulation of type 2 immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0006955///immune response+++GO:0050830///defense response to Gram-positive bacterium","IPR003961///Fibronectin type III+++IPR036116///Fibronectin type III superfamily+++IPR013783///Immunoglobulin-like fold","[I27RA_HUMAN|Reviewed]RecName: Full=Interleukin-27 receptor subunit alpha; Short=IL-27 receptor subunit alpha; Short=IL-27R subunit alpha; Short=IL-27R-alpha; Short=IL-27RA; AltName: Full=Cytokine receptor WSX-1; AltName: Full=Cytokine receptor-like 1; AltName: Full=Type I T-cell cytokine receptor; Short=TCCR; AltName: Full=ZcytoR1; Flags: Precursor;+++[A0A024R7I8_HUMAN|Unreviewed]SubName: Full=Interleukin 27 receptor, alpha, isoform CRA_a {ECO:0000313|EMBL:EAW84390.1};"]
[9481,"'SLC25A27'",20,25,22.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045177///apical part of cell+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0043025///neuronal cell body","GO:0022857///transmembrane transporter activity","GO:0035356///cellular triglyceride homeostasis+++GO:0070997///neuron death+++GO:0048839///inner ear development+++GO:0008284///positive regulation of cell proliferation+++GO:0051562///negative regulation of mitochondrial calcium ion concentration+++GO:0055085///transmembrane transport+++GO:0043066///negative regulation of apoptotic process+++GO:0010917///negative regulation of mitochondrial membrane potential+++GO:0046324///regulation of glucose import+++GO:0009409///response to cold+++GO:1902600///proton transmembrane transport","IPR040062///Mitochondrial carrier domain protein+++IPR023395///Mitochondrial carrier domain superfamily+++IPR018108///Mitochondrial substrate/solute carrier","[UCP4_HUMAN|Reviewed]RecName: Full=Mitochondrial uncoupling protein 4; Short=UCP 4; AltName: Full=Solute carrier family 25 member 27;+++[B4DHR4_HUMAN|Unreviewed]SubName: Full=Solute carrier family 25, member 27, isoform CRA_a {ECO:0000313|EMBL:EAX04298.1}; SubName: Full=cDNA FLJ57819, highly similar to Mitochondrial uncoupling protein 4 {ECO:0000313|EMBL:BAG58226.1}; SubName: Full=cDNA, FLJ78839, highly similar to Mitochondrial uncoupling protein 4 {ECO:0000313|EMBL:BAH14311.1};+++[Q5VTS8_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 4 {ECO:0000313|Ensembl:ENSP00000474781}; Flags: Fragment;+++[S4R300_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 4 {ECO:0000313|Ensembl:ENSP00000473804}; Flags: Fragment;+++[S4R3J2_HUMAN|Unreviewed]SubName: Full=Mitochondrial uncoupling protein 4 {ECO:0000313|Ensembl:ENSP00000474429}; Flags: Fragment;"]
[9501,"'RPH3AL'",30.98,21,25.99,{"$nulls":4},"GO:0030141///secretory granule+++GO:0030658///transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030667///secretory granule membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005623///cell","GO:0030274///LIM domain binding+++GO:0017137///Rab GTPase binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0008092///cytoskeletal protein binding","GO:0017157///regulation of exocytosis+++GO:0042593///glucose homeostasis+++GO:0017158///regulation of calcium ion-dependent exocytosis+++GO:0042493///response to drug+++GO:0045744///negative regulation of G protein-coupled receptor signaling pathway+++GO:0050714///positive regulation of protein secretion+++GO:0006886///intracellular protein transport+++GO:0006887///exocytosis","IPR030538///Rab effector Noc2+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR017455///Zinc finger, FYVE-related+++IPR010911///Rab-binding domain","[RPH3L_HUMAN|Reviewed]RecName: Full=Rab effector Noc2; AltName: Full=No C2 domains protein; AltName: Full=Rabphilin-3A-like protein;+++[A0A0J9YWA6_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000487877}; Flags: Fragment;+++[A0A0J9YX72_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000488277}; Flags: Fragment;+++[A8K7D5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ77349, highly similar to Homo sapiens rabphilin 3A-like (without C2 domains), mRNA {ECO:0000313|EMBL:BAF84639.1};+++[I3L181_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000458643}; Flags: Fragment;+++[I3L1Q0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459001}; Flags: Fragment;+++[I3L2G8_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459666}; Flags: Fragment;+++[I3L2I9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459716}; Flags: Fragment;+++[I3L2N0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459795}; Flags: Fragment;+++[I3L2W0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459975}; Flags: Fragment;+++[I3L2X0_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000459992}; Flags: Fragment;+++[I3L308_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460080}; Flags: Fragment;+++[I3L349_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460171}; Flags: Fragment;+++[I3L3M9_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000460580}; Flags: Fragment;+++[I3NI49_HUMAN|Unreviewed]SubName: Full=Rab effector Noc2 {ECO:0000313|Ensembl:ENSP00000461885}; Flags: Fragment;"]
[9521,"'EEF1E1'",80,79,79.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0017101///aminoacyl-tRNA synthetase multienzyme complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005730///nucleolus+++GO:0016020///membrane","GO:0005515///protein binding","GO:0006418///tRNA aminoacylation for protein translation+++GO:0008285///negative regulation of cell proliferation+++GO:0043065///positive regulation of apoptotic process+++GO:2000774///positive regulation of cellular senescence+++GO:0006412///translation+++GO:0043517///positive regulation of DNA damage response, signal transduction by p53 class mediator","IPR010987///Glutathione S-transferase, C-terminal-like+++IPR004046///Glutathione S-transferase, C-terminal+++IPR036282///Glutathione S-transferase, C-terminal domain superfamily","[MCA3_HUMAN|Reviewed]RecName: Full=Eukaryotic translation elongation factor 1 epsilon-1; AltName: Full=Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; AltName: Full=Elongation factor p18; AltName: Full=Multisynthase complex auxiliary component p18 {ECO:0000303|PubMed:19131329};+++[D6RBD7_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000424222}; SubName: Full=HCG15559, isoform CRA_d {ECO:0000313|EMBL:EAW55230.1};+++[D6RCQ0_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000425577}; Flags: Fragment;+++[H0YAH9_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000427143}; Flags: Fragment;+++[H0YAL7_HUMAN|Unreviewed]SubName: Full=Eukaryotic translation elongation factor 1 epsilon-1 {ECO:0000313|Ensembl:ENSP00000427572}; Flags: Fragment;"]
[9536,"'PTGES'",504,410,457,"01100///Metabolic pathways+++00590///Arachidonic acid metabolism",null,null,"R02265///(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase   Prostaglandin H2 <=> Prostaglandin E2","GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005739///mitochondrion+++GO:0005641///nuclear envelope lumen+++GO:0016020///membrane","GO:0043295///glutathione binding+++GO:0050220///prostaglandin-E synthase activity+++GO:0016853///isomerase activity+++GO:0004364///glutathione transferase activity","GO:0034097///response to cytokine+++GO:0002544///chronic inflammatory response+++GO:0014070///response to organic cyclic compound+++GO:0001516///prostaglandin biosynthetic process+++GO:0006631///fatty acid metabolic process+++GO:0006629///lipid metabolic process+++GO:0006693///prostaglandin metabolic process+++GO:0007165///signal transduction+++GO:0002526///acute inflammatory response+++GO:0051592///response to calcium ion+++GO:0032496///response to lipopolysaccharide+++GO:0032526///response to retinoic acid+++GO:0006749///glutathione metabolic process+++GO:0008285///negative regulation of cell proliferation+++GO:0019371///cyclooxygenase pathway+++GO:0006633///fatty acid biosynthetic process+++GO:0055114///oxidation-reduction process","IPR023352///Membrane associated eicosanoid/glutathione metabolism-like domain superfamily+++IPR001129///Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein","[PTGES_HUMAN|Reviewed]RecName: Full=Prostaglandin E synthase; EC=5.3.99.3; AltName: Full=Microsomal glutathione S-transferase 1-like 1; Short=MGST1-L1; AltName: Full=Microsomal prostaglandin E synthase 1; Short=MPGES-1; AltName: Full=p53-induced gene 12 protein;+++[A0A024R8D5_HUMAN|Unreviewed]SubName: Full=HCG30600, isoform CRA_a {ECO:0000313|EMBL:EAW87904.1};"]
[9554,"'SEC22B'",1621.77,1606.47,1614.12,"04145///Phagosome+++05134///Legionellosis+++04130///SNARE interactions in vesicular transport",{"$nulls":3},"GO:0030670///phagocytic vesicle membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0042470///melanosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0008021///synaptic vesicle+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016021///integral component of membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0030133///transport vesicle+++GO:0031201///SNARE complex","GO:0005515///protein binding+++GO:0019905///syntaxin binding+++GO:0005484///SNAP receptor activity","GO:0045732///positive regulation of protein catabolic process+++GO:1990668///vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane+++GO:0048280///vesicle fusion with Golgi apparatus+++GO:0002479///antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent+++GO:1902902///negative regulation of autophagosome assembly+++GO:0015031///protein transport+++GO:0016192///vesicle-mediated transport+++GO:0048208///COPII vesicle coating+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006890///retrograde vesicle-mediated transport, Golgi to ER","IPR010908///Longin domain+++IPR011012///Longin-like domain superfamily+++IPR001388///Synaptobrevin","[SC22B_HUMAN|Reviewed]RecName: Full=Vesicle-trafficking protein SEC22b; AltName: Full=ER-Golgi SNARE of 24 kDa; Short=ERS-24; Short=ERS24; AltName: Full=SEC22 vesicle-trafficking protein homolog B; AltName: Full=SEC22 vesicle-trafficking protein-like 1;+++[A0A087X1A9_HUMAN|Unreviewed]SubName: Full=Vesicle-trafficking protein SEC22b {ECO:0000313|Ensembl:ENSP00000484017}; Flags: Fragment;+++[I1VE16_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41826.1}; Flags: Fragment;+++[I1VE17_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41827.1}; Flags: Fragment;+++[I1VE18_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41828.1}; Flags: Fragment;+++[I1VE19_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41829.1}; Flags: Fragment;+++[I1VE20_HUMAN|Unreviewed]SubName: Full=SEC22 vesicle trafficking protein B {ECO:0000313|EMBL:AFI41830.1}; Flags: Fragment;"]
[9572,"'NR1D1'",1253,1722,1487.5,"04710///Circadian rhythm","H00250///Congenital nongoitrous hypothyroidism (CHNG)","M00430///Exon junction complex (EJC)",null,"GO:0043197///dendritic spine+++GO:0042995///cell projection+++GO:0000790///nuclear chromatin+++GO:0005737///cytoplasm+++GO:0090575///RNA polymerase II transcription factor complex+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0005654///nucleoplasm+++GO:0016604///nuclear body","GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0003714///transcription corepressor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0008270///zinc ion binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding+++GO:0004879///nuclear receptor activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001222///transcription corepressor binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0020037///heme binding+++GO:0043565///sequence-specific DNA binding+++GO:0008134///transcription factor binding+++GO:0038023///signaling receptor activity+++GO:0003707///steroid hormone receptor activity+++GO:0070888///E-box binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0044321///response to leptin+++GO:0010498///proteasomal protein catabolic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0071222///cellular response to lipopolysaccharide+++GO:0005978///glycogen biosynthetic process+++GO:0007623///circadian rhythm+++GO:0009755///hormone-mediated signaling pathway+++GO:0019216///regulation of lipid metabolic process+++GO:0030522///intracellular receptor signaling pathway+++GO:0070859///positive regulation of bile acid biosynthetic process+++GO:0061178///regulation of insulin secretion involved in cellular response to glucose stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0035947///regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter+++GO:0010871///negative regulation of receptor biosynthetic process+++GO:0033993///response to lipid+++GO:0042632///cholesterol homeostasis+++GO:0061469///regulation of type B pancreatic cell proliferation+++GO:0045598///regulation of fat cell differentiation+++GO:0048511///rhythmic process+++GO:0060086///circadian temperature homeostasis+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0042752///regulation of circadian rhythm+++GO:0032922///circadian regulation of gene expression+++GO:0030154///cell differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0007275///multicellular organism development+++GO:0034144///negative regulation of toll-like receptor 4 signaling pathway+++GO:0043401///steroid hormone mediated signaling pathway","IPR035500///Nuclear hormone receptor-like domain superfamily+++IPR000536///Nuclear hormone receptor, ligand-binding domain+++IPR001628///Zinc finger, nuclear hormone receptor-type+++IPR001728///Thyroid hormone receptor+++IPR013088///Zinc finger, NHR/GATA-type+++IPR001723///Nuclear hormone receptor","[NR1D1_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group D member 1; AltName: Full=Rev-erbA-alpha; AltName: Full=V-erbA-related protein 1; Short=EAR-1;+++[F1D8S3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA-alpha {ECO:0000313|EMBL:ADZ17372.1}; SubName: Full=Nuclear receptor subfamily 1, group D, member 1 {ECO:0000313|EMBL:EAW60636.1};"]
[9589,"'WTAP'",754,709,731.5,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0036396///RNA N6-methyladenosine methyltransferase complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane","GO:0005515///protein binding","GO:0007275///multicellular organism development+++GO:0006397///mRNA processing+++GO:0008380///RNA splicing+++GO:0007049///cell cycle+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0080009///mRNA methylation","IPR029732///WTAP/Mum2 family+++IPR033757///Pre-mRNA-splicing regulator WTAP","[FL2D_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing regulator WTAP {ECO:0000305}; AltName: Full=Female-lethal(2)D homolog {ECO:0000303|PubMed:12444081}; Short=hFL(2)D {ECO:0000303|PubMed:12444081}; AltName: Full=WT1-associated protein {ECO:0000303|PubMed:11001926}; AltName: Full=Wilms tumor 1-associating protein {ECO:0000303|PubMed:11001926};+++[A0A087X1R4_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing regulator WTAP {ECO:0000313|Ensembl:ENSP00000484404}; SubName: Full=Wilms tumor 1 associated protein, isoform CRA_f {ECO:0000313|EMBL:EAW47628.1};"]
[9616,"'RNF7'",727.94,529,628.47,"04120///Ubiquitin mediated proteolysis",null,"M00388///ECS complex",null,"GO:0005737///cytoplasm+++GO:0001750///photoreceptor outer segment+++GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0001917///photoreceptor inner segment+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0005680///anaphase-promoting complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0043224///nuclear SCF ubiquitin ligase complex+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0005654///nucleoplasm+++GO:0031462///Cul2-RING ubiquitin ligase complex","GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0097602///cullin family protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0004864///protein phosphatase inhibitor activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0019788///NEDD8 transferase activity+++GO:0002046///opsin binding+++GO:0005507///copper ion binding+++GO:0051219///phosphoprotein binding","GO:0007166///cell surface receptor signaling pathway+++GO:0022400///regulation of rhodopsin mediated signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0032515///negative regulation of phosphoprotein phosphatase activity+++GO:0051775///response to redox state+++GO:0007165///signal transduction+++GO:0016056///rhodopsin mediated signaling pathway+++GO:0045116///protein neddylation","IPR024766///Zinc finger, RING-H2-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type","[RBX2_HUMAN|Reviewed]RecName: Full=RING-box protein 2; Short=Rbx2; AltName: Full=CKII beta-binding protein 1; Short=CKBBP1; AltName: Full=RING finger protein 7; AltName: Full=Regulator of cullins 2; AltName: Full=Sensitive to apoptosis gene protein;+++[C9JSX4_HUMAN|Unreviewed]SubName: Full=S-arrestin {ECO:0000313|Ensembl:ENSP00000409475}; Flags: Fragment;+++[E7ESX4_HUMAN|Unreviewed]SubName: Full=S-arrestin {ECO:0000313|Ensembl:ENSP00000408937}; Flags: Fragment;+++[F8WCN5_HUMAN|Unreviewed]SubName: Full=S-arrestin {ECO:0000313|Ensembl:ENSP00000404733};+++[F8WEU8_HUMAN|Unreviewed]SubName: Full=RING-box protein 2 {ECO:0000313|Ensembl:ENSP00000419979};"]
[9637,"'FEZ2'",447,526,486.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030424///axon+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0007399///nervous system development+++GO:0007411///axon guidance+++GO:1902902///negative regulation of autophagosome assembly","IPR015641///Fasciculation and elongation protein zeta 2+++IPR011680///Fasciculation and elongation protein zeta, FEZ","[FEZ2_HUMAN|Reviewed]RecName: Full=Fasciculation and elongation protein zeta-2; AltName: Full=Zygin II; AltName: Full=Zygin-2;+++[F8W6C0_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta-2 {ECO:0000313|Ensembl:ENSP00000350685}; Flags: Fragment;+++[F8WB37_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta-2 {ECO:0000313|Ensembl:ENSP00000410879};+++[G3V0F5_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta 2 (Zygin II), isoform CRA_f {ECO:0000313|EMBL:EAX00425.1}; SubName: Full=Fasciculation and elongation protein zeta-2 {ECO:0000313|Ensembl:ENSP00000390985};+++[H7C0L4_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta-2 {ECO:0000313|Ensembl:ENSP00000395619}; Flags: Fragment;+++[H7C0W1_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta-2 {ECO:0000313|Ensembl:ENSP00000396982}; Flags: Fragment;+++[H7C434_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta-2 {ECO:0000313|Ensembl:ENSP00000415325}; Flags: Fragment;+++[Q0D2I6_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta 2 (Zygin II) {ECO:0000313|EMBL:AAI10387.1};+++[Q3ZCX5_HUMAN|Unreviewed]SubName: Full=FEZ2 protein {ECO:0000313|EMBL:AAH18032.1}; Flags: Fragment;+++[Q6P2J5_HUMAN|Unreviewed]SubName: Full=FEZ2 protein {ECO:0000313|EMBL:AAH64484.1}; Flags: Fragment;+++[Q7Z5U3_HUMAN|Unreviewed]SubName: Full=FEZ2 protein {ECO:0000313|EMBL:AAH54043.1}; Flags: Fragment;+++[Q7Z674_HUMAN|Unreviewed]SubName: Full=Fasciculation and elongation protein zeta 2 (Zygin II), isoform CRA_d {ECO:0000313|EMBL:EAX00423.1}; SubName: Full=Fasciculation and elongation protein zeta-2 {ECO:0000313|Ensembl:ENSP00000305843};"]
[9652,"'TTC37'",681,970,825.5,"03018///RNA degradation","H01805///Tricho-hepato-enteric syndrome","M00392///Ski complex",null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0035327///transcriptionally active chromatin+++GO:0055087///Ski complex+++GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0005515///protein binding","GO:0006401///RNA catabolic process+++GO:0043928///exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR019734///Tetratricopeptide repeat+++IPR039226///Ski3/TTC37+++IPR013026///Tetratricopeptide repeat-containing domain","[TTC37_HUMAN|Reviewed]RecName: Full=Tetratricopeptide repeat protein 37; Short=TPR repeat protein 37; AltName: Full=SKI3 homolog; Short=Ski3; AltName: Full=Tricho-hepatic-enteric syndrome protein; Short=Thespin;+++[D6RCE2_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 37 {ECO:0000313|Ensembl:ENSP00000423742}; Flags: Fragment;+++[D6RDA0_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 37 {ECO:0000313|Ensembl:ENSP00000425403}; Flags: Fragment;+++[H0Y915_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 37 {ECO:0000313|Ensembl:ENSP00000422749}; Flags: Fragment;+++[H0Y964_HUMAN|Unreviewed]SubName: Full=Tetratricopeptide repeat protein 37 {ECO:0000313|Ensembl:ENSP00000423141}; Flags: Fragment;"]
[9668,"'ZNF432'",136,160,148,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR036051///KRAB domain superfamily+++IPR001909///Krueppel-associated box+++IPR013087///Zinc finger C2H2-type","[ZN432_HUMAN|Reviewed]RecName: Full=Zinc finger protein 432;+++[A0A024R4I3_HUMAN|Unreviewed]SubName: Full=HCG2008146, isoform CRA_c {ECO:0000313|EMBL:EAW72062.1};+++[M0QZ71_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 432 {ECO:0000313|Ensembl:ENSP00000470341};+++[M0R0E2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 432 {ECO:0000313|Ensembl:ENSP00000471172}; Flags: Fragment;+++[M0R0H8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 432 {ECO:0000313|Ensembl:ENSP00000471244}; Flags: Fragment;+++[M0R258_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 432 {ECO:0000313|Ensembl:ENSP00000472337}; Flags: Fragment;"]
[9683,"'N4BP1'",1444,1814,1629,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0016605///PML body+++GO:0005634///nucleus","GO:0005515///protein binding","GO:0031397///negative regulation of protein ubiquitination+++GO:0032435///negative regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0034644///cellular response to UV","IPR021869///Ribonuclease Zc3h12a-like, NYN domain","[N4BP1_HUMAN|Reviewed]RecName: Full=NEDD4-binding protein 1; Short=N4BP1;+++[I3L3R7_HUMAN|Unreviewed]SubName: Full=NEDD4-binding protein 1 {ECO:0000313|Ensembl:ENSP00000460667}; Flags: Fragment;"]
[97,"'ACYP1'",27,18,22.5,"00620///Pyruvate metabolism+++00627///Aminobenzoate degradation+++01120///Microbial metabolism in diverse environments",null,null,"R00317///Acetyl phosphate phosphohydrolase   Acetyl phosphate + H2O <=> Acetate + Orthophosphate+++R01515///3-Phospho-D-glyceroyl phosphate phosphohydrolase   3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate+++R01421///Benzoyl phosphate phosphohydrolase   Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate","GO:0001673///male germ cell nucleus+++GO:0005634///nucleus+++GO:0000795///synaptonemal complex+++GO:0032300///mismatch repair complex+++GO:0005712///chiasma","GO:0003998///acylphosphatase activity+++GO:0016787///hydrolase activity","GO:0006796///phosphate-containing compound metabolic process","IPR036046///Acylphosphatase-like domain superfamily+++IPR017968///Acylphosphatase, conserved site+++IPR020456///Acylphosphatase+++IPR001792///Acylphosphatase-like domain","[ACYP1_HUMAN|Reviewed]RecName: Full=Acylphosphatase-1; EC=3.6.1.7; AltName: Full=Acylphosphatase, erythrocyte isozyme; AltName: Full=Acylphosphatase, organ-common type isozyme; AltName: Full=Acylphosphate phosphohydrolase 1;+++[G3V2U7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[G3V3F8_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-1 {ECO:0000313|Ensembl:ENSP00000451220};+++[G3V597_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-1 {ECO:0000313|Ensembl:ENSP00000452249};"]
[9715,"'FAM131B'",132,128,130,{"$nulls":4},"GO:0005829///cytosol+++GO:0005654///nucleoplasm","GO:0005515///protein binding",null,"IPR026782///Protein FAM131","[F131B_HUMAN|Reviewed]RecName: Full=Protein FAM131B;+++[D3DXE4_HUMAN|Unreviewed]SubName: Full=KIAA0773 gene product, isoform CRA_b {ECO:0000313|EMBL:EAW51856.1};+++[E5RI17_HUMAN|Unreviewed]SubName: Full=Protein FAM131B {ECO:0000313|Ensembl:ENSP00000430805};+++[E5RJ60_HUMAN|Unreviewed]SubName: Full=Protein FAM131B {ECO:0000313|Ensembl:ENSP00000430601};+++[H0Y3V6_HUMAN|Unreviewed]SubName: Full=Protein FAM131B {ECO:0000313|Ensembl:ENSP00000386396}; Flags: Fragment;+++[O94871_HUMAN|Unreviewed]SubName: Full=KIAA0773 protein {ECO:0000313|EMBL:BAA34493.2}; Flags: Fragment;"]
[9722,"'NOS1AP'",18,44,31,"04713///Circadian entrainment",{"$nulls":3},"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0042383///sarcolemma+++GO:0005739///mitochondrion+++GO:1990454///L-type voltage-gated calcium channel complex+++GO:0005901///caveola+++GO:0005634///nucleus+++GO:1902937///inward rectifier potassium channel complex+++GO:0033017///sarcoplasmic reticulum membrane+++GO:0098978///glutamatergic synapse+++GO:0030018///Z disc+++GO:0031965///nuclear membrane+++GO:0030315///T-tubule","GO:0005515///protein binding+++GO:0050998///nitric-oxide synthase binding","GO:1902514///regulation of calcium ion transmembrane transport via high voltage-gated calcium channel+++GO:0050999///regulation of nitric-oxide synthase activity+++GO:0098901///regulation of cardiac muscle cell action potential+++GO:0045429///positive regulation of nitric oxide biosynthetic process+++GO:0051000///positive regulation of nitric-oxide synthase activity+++GO:0098974///postsynaptic actin cytoskeleton organization+++GO:0045428///regulation of nitric oxide biosynthetic process+++GO:0003062///regulation of heart rate by chemical signal+++GO:1901841///regulation of high voltage-gated calcium channel activity+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1902261///positive regulation of delayed rectifier potassium channel activity+++GO:1901381///positive regulation of potassium ion transmembrane transport+++GO:1903762///positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:2000170///positive regulation of peptidyl-cysteine S-nitrosylation+++GO:0010750///positive regulation of nitric oxide mediated signal transduction+++GO:0010628///positive regulation of gene expression","IPR006020///PTB/PI domain+++IPR011993///PH-like domain superfamily","[CAPON_HUMAN|Reviewed]RecName: Full=Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein; AltName: Full=C-terminal PDZ ligand of neuronal nitric oxide synthase protein; AltName: Full=Nitric oxide synthase 1 adaptor protein;+++[E9PIP8_HUMAN|Unreviewed]SubName: Full=Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein {ECO:0000313|Ensembl:ENSP00000435711}; Flags: Fragment;+++[E9PSG0_HUMAN|Unreviewed]SubName: Full=Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein {ECO:0000313|Ensembl:ENSP00000396713};"]
[9723,"'SEMA3E'",89.01,101.34,95.175,"04360///Axon guidance","H00255///Hypogonadotropic hypogonadism+++H00556///CHARGE syndrome",null,null,"GO:0005887///integral component of plasma membrane+++GO:0005615///extracellular space+++GO:0005576///extracellular region","GO:0045499///chemorepellent activity+++GO:0030215///semaphorin receptor binding+++GO:0038191///neuropilin binding+++GO:0005515///protein binding","GO:2000249///regulation of actin cytoskeleton reorganization+++GO:0007399///nervous system development+++GO:0050808///synapse organization+++GO:0030154///cell differentiation+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0048843///negative regulation of axon extension involved in axon guidance+++GO:0008360///regulation of cell shape+++GO:0001569///branching involved in blood vessel morphogenesis+++GO:0030335///positive regulation of cell migration+++GO:0001953///negative regulation of cell-matrix adhesion+++GO:0016525///negative regulation of angiogenesis+++GO:0002040///sprouting angiogenesis+++GO:0007275///multicellular organism development+++GO:0001525///angiogenesis+++GO:0050919///negative chemotaxis+++GO:0001755///neural crest cell migration","IPR016201///PSI domain+++IPR013783///Immunoglobulin-like fold+++IPR036352///Sema domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR007110///Immunoglobulin-like domain+++IPR013151///Immunoglobulin+++IPR001627///Sema domain+++IPR036179///Immunoglobulin-like domain superfamily+++IPR015513///Semaphorin 3E+++IPR027231///Semaphorin","[SEM3E_HUMAN|Reviewed]RecName: Full=Semaphorin-3E; Flags: Precursor;+++[A0A2R8YCX5_HUMAN|Unreviewed]SubName: Full=Semaphorin-3E {ECO:0000313|Ensembl:ENSP00000494064};+++[F8WCZ5_HUMAN|Unreviewed]SubName: Full=Semaphorin-3E {ECO:0000313|Ensembl:ENSP00000415184};"]
[9724,"'UTP14C'",333.88,479.35,406.615,"03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0005829///cytosol+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0032040///small-subunit processome","GO:0005515///protein binding","GO:0006364///rRNA processing+++GO:0042254///ribosome biogenesis+++GO:0030154///cell differentiation+++GO:0007275///multicellular organism development+++GO:0007283///spermatogenesis+++GO:0051321///meiotic cell cycle","IPR006709///Small-subunit processome, Utp14","[UT14C_HUMAN|Reviewed]RecName: Full=U3 small nucleolar RNA-associated protein 14 homolog C;+++[A0A024RDV0_HUMAN|Unreviewed]SubName: Full=HCG1811699, isoform CRA_a {ECO:0000313|EMBL:EAX08903.1};+++[Q08E77_HUMAN|Unreviewed]SubName: Full=UTP14, U3 small nucleolar ribonucleoprotein, homolog C (Yeast) {ECO:0000313|EMBL:AAI22537.1};"]
[9725,"'TMEM63A'",236,284,260,{"$nulls":4},"GO:0005764///lysosome+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0070062///extracellular exosome+++GO:0005765///lysosomal membrane+++GO:0005886///plasma membrane+++GO:0035579///specific granule membrane+++GO:0005815///microtubule organizing center+++GO:0070821///tertiary granule membrane","GO:0003676///nucleic acid binding+++GO:0005227///calcium activated cation channel activity","GO:0034220///ion transmembrane transport+++GO:0043312///neutrophil degranulation+++GO:0006811///ion transport","IPR003864///Calcium-dependent channel, 7TM region, putative phosphate+++IPR032880///Calcium permeable stress-gated cation channel 1, N-terminal transmembrane domain+++IPR035979///RNA-binding domain superfamily+++IPR026957///CSC1-like protein 1+++IPR027815///10TM putative phosphate transporter, cytosolic domain","[CSCL1_HUMAN|Reviewed]RecName: Full=CSC1-like protein 1; AltName: Full=Transmembrane protein 63A;+++[A0A024R3T3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 63A, isoform CRA_a {ECO:0000313|EMBL:EAW69759.1};+++[Q2HIZ8_HUMAN|Unreviewed]SubName: Full=CSC1-like protein 1 {ECO:0000313|Ensembl:ENSP00000445237}; SubName: Full=TMEM63A protein {ECO:0000313|EMBL:AAI13812.1};+++[X6RI56_HUMAN|Unreviewed]SubName: Full=CSC1-like protein 1 {ECO:0000313|Ensembl:ENSP00000409002}; Flags: Fragment;"]
[9726,"'ZNF646'",569,714,641.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZN646_HUMAN|Reviewed]RecName: Full=Zinc finger protein 646;+++[C9J3L0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 646 {ECO:0000313|Ensembl:ENSP00000391271}; Flags: Fragment;+++[H3BSD0_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 646 {ECO:0000313|Ensembl:ENSP00000456651}; Flags: Fragment;"]
[9727,"'RAB11FIP3'",824,777,800.5,"04144///Endocytosis",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00050///Guanine ribonucleotide biosynthesis IMP => GDP,GTP","R01857///ATP:dGDP phosphotransferase ATP + dGDP <=> ADP + dGTP+++R02326///ATP:dCDP phosphotransferase ATP + dCDP <=> ADP + dCTP+++R03530///ATP:dIDP phosphotransferase ATP + dIDP <=> ADP + dITP+++R00139///ATP:2'-deoxy-5-hydroxymethylcytidine-5'-diphosphate phosphotransferase 2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate + ATP <=> 2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate + ADP+++R00156///ATP:UDP phosphotransferase ATP + UDP <=> ADP + UTP+++R00722///ATP:IDP phosphotransferase ATP + IDP <=> ADP + ITP+++R02331///ATP:dUDP phosphotransferase ATP + dUDP <=> ADP + dUTP+++R00124///ATP:ADP phosphatransferase ATP + ADP <=> ADP + ATP+++R11895///ATP:5-fluorodeoxyuridine-diphosphate phosphotransferase ATP + 5-Fluorodeoxyuridine diphosphate <=> ADP + 5-Fluorodeoxyuridine triphosphate+++R00570///ATP:CDP phosphotransferase ATP + CDP <=> ADP + CTP+++R01137///ATP:dADP phosphotransferase ATP + dADP <=> ADP + dATP+++R11894///ATP:5-fluorouridine-diphosphate phosphotransferase ATP + 5-Fluorouridine diphosphate <=> ADP + 5-Fluorouridine triphosphate+++R00330///ATP:GDP phosphotransferase ATP + GDP <=> ADP + GTP+++R02093///ATP:dTDP phosphotransferase ATP + dTDP <=> ADP + dTTP","GO:0030496///midbody+++GO:0045171///intercellular bridge+++GO:0043231///intracellular membrane-bounded organelle+++GO:0055037///recycling endosome+++GO:0005654///nucleoplasm+++GO:0005623///cell+++GO:0005815///microtubule organizing center+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0030139///endocytic vesicle+++GO:0055038///recycling endosome membrane+++GO:0032154///cleavage furrow+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0030306///ADP-ribosylation factor binding+++GO:0046872///metal ion binding+++GO:0051959///dynein light intermediate chain binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0005509///calcium ion binding+++GO:0017137///Rab GTPase binding","GO:0070164///negative regulation of adiponectin secretion+++GO:0032465///regulation of cytokinesis+++GO:0016192///vesicle-mediated transport+++GO:0032456///endocytic recycling+++GO:0061512///protein localization to cilium+++GO:0051301///cell division+++GO:0007049///cell cycle","IPR037245///FIP-RBD, C-terminal domain superfamily+++IPR011992///EF-hand domain pair+++IPR002048///EF-hand domain+++IPR032920///Rab11 family-interacting protein 3+++IPR019018///Rab-binding domain FIP-RBD","[RFIP3_HUMAN|Reviewed]RecName: Full=Rab11 family-interacting protein 3; Short=FIP3-Rab11; Short=Rab11-FIP3; AltName: Full=Arfophilin-1; AltName: Full=EF hands-containing Rab-interacting protein; Short=Eferin; AltName: Full=MU-MB-17.148;+++[A0A0A0MSV1_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000404331}; Flags: Fragment;+++[A0A0J9YWM0_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488023}; Flags: Fragment;+++[A0A0J9YWV4_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488133}; Flags: Fragment;+++[A0A0J9YXZ3_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488615}; Flags: Fragment;+++[A0A0J9YY48_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000488688}; Flags: Fragment;+++[F6X994_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000399614}; Flags: Fragment;+++[H0Y7F9_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000412502}; Flags: Fragment;+++[X6RFI8_HUMAN|Unreviewed]SubName: Full=Rab11 family-interacting protein 3 {ECO:0000313|Ensembl:ENSP00000399644}; Flags: Fragment;"]
[9728,"'SECISBP2L'",379,534,456.5,{"$nulls":4},"GO:1990904///ribonucleoprotein complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0003730///mRNA 3'-UTR binding","GO:0001514///selenocysteine incorporation","IPR040051///Selenocysteine insertion sequence-binding protein 2+++IPR029064///50S ribosomal protein L30e-like+++IPR004038///Ribosomal protein L7Ae/L30e/S12e/Gadd45","[SBP2L_HUMAN|Reviewed]RecName: Full=Selenocysteine insertion sequence-binding protein 2-like; Short=SECIS-binding protein 2-like;+++[A0A024R5R0_HUMAN|Unreviewed]SubName: Full=KIAA0256 gene product, isoform CRA_a {ECO:0000313|EMBL:EAW77362.1};+++[H0YKY4_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000452987}; Flags: Fragment;+++[H0YNT4_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000454144}; Flags: Fragment;+++[J3KPI1_HUMAN|Unreviewed]SubName: Full=Selenocysteine insertion sequence-binding protein 2-like {ECO:0000313|Ensembl:ENSP00000370314}; Flags: Fragment;"]
[9729,"'KIAA0408'",28.54,3.66,16.1,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0005515///protein binding",null,"IPR027882///Domain of unknown function DUF4482","[K0408_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0408;+++[E9PQS0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000434384}; Flags: Fragment;+++[H0YEM8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0408 {ECO:0000313|Ensembl:ENSP00000436178}; Flags: Fragment;"]
[973,"'CD79A'",50,39,44.5,"04662///B cell receptor signaling pathway+++05340///Primary immunodeficiency","H00085///Agammaglobulinemias",null,null,"GO:0016021///integral component of membrane+++GO:0045121///membrane raft+++GO:0016020///membrane+++GO:0005771///multivesicular body+++GO:0005886///plasma membrane+++GO:0019815///B cell receptor complex+++GO:0009897///external side of plasma membrane","GO:0004888///transmembrane signaling receptor activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding","GO:0051289///protein homotetramerization+++GO:0002376///immune system process+++GO:0002250///adaptive immune response+++GO:0050853///B cell receptor signaling pathway+++GO:0030183///B cell differentiation+++GO:0007166///cell surface receptor signaling pathway+++GO:0042100///B cell proliferation+++GO:0042113///B cell activation","IPR003110///Phosphorylated immunoreceptor signalling ITAM+++IPR013151///Immunoglobulin+++IPR003599///Immunoglobulin subtype+++IPR003598///Immunoglobulin subtype 2+++IPR039695///B-cell antigen receptor complex-associated protein alpha/beta chain+++IPR007110///Immunoglobulin-like domain+++IPR013783///Immunoglobulin-like fold+++IPR036179///Immunoglobulin-like domain superfamily","[CD79A_HUMAN|Reviewed]RecName: Full=B-cell antigen receptor complex-associated protein alpha chain; AltName: Full=Ig-alpha; AltName: Full=MB-1 membrane glycoprotein; AltName: Full=Membrane-bound immunoglobulin-associated protein; AltName: Full=Surface IgM-associated protein; AltName: CD_antigen=CD79a; Flags: Precursor;+++[M0QX61_HUMAN|Unreviewed]SubName: Full=B-cell antigen receptor complex-associated protein alpha chain {ECO:0000313|Ensembl:ENSP00000468922}; Flags: Fragment;"]
[9730,"'DCAF1'",312,341,326.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0008180///COP9 signalosome+++GO:0001650///fibrillar center+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex","GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:1990244///histone kinase activity (H2A-T120 specific)+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding+++GO:0030331///estrogen receptor binding","GO:0030183///B cell differentiation+++GO:0016032///viral process+++GO:0033151///V(D)J recombination+++GO:0016310///phosphorylation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1990245///histone H2A-T120 phosphorylation+++GO:0006325///chromatin organization+++GO:0016567///protein ubiquitination+++GO:0035212///cell competition in a multicellular organism","IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR016024///Armadillo-type fold+++IPR033270///VPRBP/DCAF1 family+++IPR036322///WD40-repeat-containing domain superfamily+++IPR006594///LIS1 homology motif","[DCAF1_HUMAN|Reviewed]RecName: Full=DDB1- and CUL4-associated factor 1 {ECO:0000312|HGNC:HGNC:30911}; AltName: Full=HIV-1 Vpr-binding protein; Short=VprBP; AltName: Full=Serine/threonine-protein kinase VPRBP; EC=2.7.11.1; AltName: Full=Vpr-interacting protein;"]
[9731,"'CEP104'",523.93,518,520.965,null,"H00530///Joubert syndrome",null,null,"GO:0042995///cell projection+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0005814///centriole+++GO:0000922///spindle pole","GO:0016594///glycine binding+++GO:0016595///glutamate binding+++GO:0016596///thienylcyclohexylpiperidine binding+++GO:0005515///protein binding",null,"IPR011989///Armadillo-like helical+++IPR016024///Armadillo-type fold+++IPR008979///Galactose-binding-like domain superfamily+++IPR034085///TOG domain","[CE104_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 104 kDa; Short=Cep104;+++[H7C0J5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000395283}; Flags: Fragment;+++[J3QLL3_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000463605}; Flags: Fragment;+++[Q5SR26_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000411927}; Flags: Fragment;+++[Q5SR27_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 104 kDa {ECO:0000313|Ensembl:ENSP00000394989}; Flags: Fragment;"]
[9732,"'DOCK4'",41,28,34.5,"04015///Rap1 signaling pathway",{"$nulls":3},"GO:0016020///membrane+++GO:0005730///nucleolus+++GO:0005794///Golgi apparatus+++GO:0042995///cell projection+++GO:0005829///cytosol+++GO:0032420///stereocilium+++GO:0032421///stereocilium bundle+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0005096///GTPase activator activity+++GO:0030971///receptor tyrosine kinase binding+++GO:0048365///Rac GTPase binding+++GO:0017124///SH3 domain binding+++GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0030165///PDZ domain binding+++GO:0005515///protein binding","GO:1904694///negative regulation of vascular smooth muscle contraction+++GO:0007264///small GTPase mediated signal transduction+++GO:0060326///cell chemotaxis+++GO:1904754///positive regulation of vascular associated smooth muscle cell migration+++GO:0043547///positive regulation of GTPase activity","IPR032376///Dedicator of cytokinesis, N-terminal domain+++IPR001452///SH3 domain+++IPR010703///Dedicator of cytokinesis, C-terminal+++IPR037811///Dedicator of cytokinesis B, C2 domain+++IPR035769///Dedicator of cytokinesis 4, SH3 domain+++IPR037014///Dedicator of cytokinesis 4+++IPR035892///C2 domain superfamily+++IPR027357///DHR-2 domain+++IPR036028///SH3-like domain superfamily+++IPR027007///DHR-1 domain+++IPR026791///Dedicator of cytokinesis","[DOCK4_HUMAN|Reviewed]RecName: Full=Dedicator of cytokinesis protein 4;+++[A0A024R749_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4, isoform CRA_a {ECO:0000313|EMBL:EAW83455.1};+++[A0A2X0SFR8_HUMAN|Unreviewed]SubName: Full=DOCK4 {ECO:0000313|EMBL:SPT35744.1}; Flags: Fragment;+++[A4D0S8_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:EAL24377.1};+++[C9J637_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406468}; Flags: Fragment;+++[C9J7D9_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000406298}; Flags: Fragment;+++[C9JDB3_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000403504}; Flags: Fragment;+++[F5GXW1_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000440944};+++[F8WES4_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000393486};+++[H0Y599_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000397412}; Flags: Fragment;+++[H0Y7H7_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis protein 4 {ECO:0000313|Ensembl:ENSP00000412834}; Flags: Fragment;+++[Q149N2_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17695.1};+++[Q149N5_HUMAN|Unreviewed]SubName: Full=DOCK4 protein {ECO:0000313|EMBL:AAI17690.1};+++[Q149N6_HUMAN|Unreviewed]SubName: Full=Dedicator of cytokinesis 4 {ECO:0000313|EMBL:AAI17689.1};+++[Q75MU6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DOCK4 {ECO:0000313|EMBL:AAS07431.1}; Flags: Fragment;"]
[9733,"'SART3'",451,443,447,null,"H00791///Disseminated superficial actinic porokeratosis (DSAP)",null,null,"GO:0071002///U4atac/U6atac snRNP+++GO:0061574///ASAP complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005691///U6atac snRNP+++GO:0015030///Cajal body+++GO:0046540///U4/U6 x U5 tri-snRNP complex+++GO:0005634///nucleus+++GO:0071001///U4/U6 snRNP","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0042393///histone binding+++GO:0030624///U6atac snRNA binding+++GO:0003676///nucleic acid binding+++GO:1990381///ubiquitin-specific protease binding+++GO:0030621///U4 snRNA binding+++GO:0017070///U6 snRNA binding","GO:0010468///regulation of gene expression+++GO:0000902///cell morphogenesis+++GO:0000244///spliceosomal tri-snRNP complex assembly+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome+++GO:0048872///homeostasis of number of cells+++GO:0071425///hematopoietic stem cell proliferation+++GO:0006334///nucleosome assembly+++GO:0000387///spliceosomal snRNP assembly+++GO:1903586///positive regulation of histone deubiquitination+++GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006396///RNA processing+++GO:0006397///mRNA processing","IPR003107///HAT (Half-A-TPR) repeat+++IPR034218///SART3, RNA recognition motif 2+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR008669///LSM-interacting domain+++IPR000504///RNA recognition motif domain+++IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR034217///SART3, RNA recognition motif 1","[SART3_HUMAN|Reviewed]RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000305}; Short=SART-3 {ECO:0000312|EMBL:BAA78384.1}; AltName: Full=Tat-interacting protein of 110 kDa {ECO:0000303|PubMed:11959860}; Short=Tip110 {ECO:0000303|PubMed:11959860}; AltName: Full=p110 nuclear RNA-binding protein {ECO:0000303|PubMed:12032085};+++[F8VV04_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449386}; Flags: Fragment;+++[F8VVK9_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000449602}; Flags: Fragment;+++[F8VZM2_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447324}; Flags: Fragment;+++[F8W667_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000446577};+++[H0YHU8_HUMAN|Unreviewed]SubName: Full=Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000313|Ensembl:ENSP00000447875}; Flags: Fragment;"]
[9734,"'HDAC9'",549,714.01,631.505,"05034///Alcoholism+++05165///Human papillomavirus infection+++05203///Viral carcinogenesis","H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0005634///nucleus+++GO:0000118///histone deacetylase complex+++GO:0005667///transcription factor complex+++GO:0005829///cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0035097///histone methyltransferase complex","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0071889///14-3-3 protein binding+++GO:0070491///repressing transcription factor binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0004407///histone deacetylase activity+++GO:0008134///transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0033558///protein deacetylase activity+++GO:0003682///chromatin binding+++GO:0019901///protein kinase binding+++GO:0042826///histone deacetylase binding+++GO:0033613///activating transcription factor binding+++GO:0005080///protein kinase C binding+++GO:0003714///transcription corepressor activity+++GO:0016787///hydrolase activity","GO:0006954///inflammatory response+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0006325///chromatin organization+++GO:0090050///positive regulation of cell migration involved in sprouting angiogenesis+++GO:0032703///negative regulation of interleukin-2 production+++GO:0042113///B cell activation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0016575///histone deacetylation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0007507///heart development+++GO:0032869///cellular response to insulin stimulus+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0030182///neuron differentiation+++GO:0007043///cell-cell junction assembly+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0001570///vasculogenesis+++GO:0030183///B cell differentiation+++GO:0001975///response to amphetamine+++GO:0034983///peptidyl-lysine deacetylation","IPR023696///Ureohydrolase domain superfamily+++IPR023801///Histone deacetylase domain+++IPR024643///Histone deacetylase, glutamine rich N-terminal domain+++IPR017320///Histone deacetylase class II, eukaryotic+++IPR000286///Histone deacetylase family+++IPR037138///Histone deacetylase domain superfamily","[HDAC9_HUMAN|Reviewed]RecName: Full=Histone deacetylase 9; Short=HD9; EC=3.5.1.98; AltName: Full=Histone deacetylase 7B; Short=HD7; Short=HD7b; AltName: Full=Histone deacetylase-related protein; AltName: Full=MEF2-interacting transcription repressor MITR;+++[B5MCF1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000384017};+++[B7Z3P7_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ79008, highly similar to Histone deacetylase 9 {ECO:0000313|EMBL:BAH14480.1};+++[C9IZS0_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000412497}; Flags: Fragment;+++[C9J1W4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000392564}; Flags: Fragment;+++[C9J835_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000411422}; Flags: Fragment;+++[C9JD56_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000404763}; Flags: Fragment;+++[C9JLX1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000409003}; Flags: Fragment;+++[F8WDS2_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 9 {ECO:0000313|Ensembl:ENSP00000415095};+++[Q75N08_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07409.1}; Flags: Fragment;+++[Q75N09_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07402.1}; Flags: Fragment;+++[Q75N10_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07401.1}; Flags: Fragment;+++[Q75N14_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07423.1}; Flags: Fragment;+++[Q75N15_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07424.1}; Flags: Fragment;+++[Q75N16_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAS07422.1}; Flags: Fragment;+++[Q9Y6V1_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein HDAC9 {ECO:0000313|EMBL:AAD15364.2};"]
[9735,"'KNTC1'",57,59,58,{"$nulls":4},"GO:0005829///cytosol+++GO:0005828///kinetochore microtubule+++GO:0000777///condensed chromosome kinetochore+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0015629///actin cytoskeleton+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0005886///plasma membrane+++GO:0000776///kinetochore+++GO:0000922///spindle pole+++GO:1990423///RZZ complex+++GO:0005856///cytoskeleton+++GO:0000775///chromosome, centromeric region","GO:0005515///protein binding","GO:0065003///protein-containing complex assembly+++GO:0007096///regulation of exit from mitosis+++GO:0007049///cell cycle+++GO:0007093///mitotic cell cycle checkpoint+++GO:0051301///cell division","IPR019527///RZZ complex, subunit KNTC1/ROD, C-terminal+++IPR036322///WD40-repeat-containing domain superfamily","[KNTC1_HUMAN|Reviewed]RecName: Full=Kinetochore-associated protein 1; AltName: Full=Rough deal homolog; Short=HsROD; Short=Rod; Short=hRod;+++[E7ES84_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397992};+++[F5H5V0_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000408760};+++[H0YFL5_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000439119}; Flags: Fragment;+++[J3KQF2_HUMAN|Unreviewed]SubName: Full=Kinetochore-associated protein 1 {ECO:0000313|Ensembl:ENSP00000397140}; Flags: Fragment;"]
[9736,"'USP34'",1060,1322,1191,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0016787///hydrolase activity+++GO:0008234///cysteine-type peptidase activity+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0005515///protein binding+++GO:0004197///cysteine-type endopeptidase activity","GO:0071108///protein K48-linked deubiquitination+++GO:0006508///proteolysis+++GO:0090263///positive regulation of canonical Wnt signaling pathway+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0031647///regulation of protein stability+++GO:0016579///protein deubiquitination","IPR028889///Ubiquitin specific protease domain+++IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase+++IPR018200///Ubiquitin specific protease, conserved site+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR016024///Armadillo-type fold","[UBP34_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 34; EC=3.4.19.12 {ECO:0000269|PubMed:14715245, ECO:0000269|PubMed:21383061}; AltName: Full=Deubiquitinating enzyme 34; AltName: Full=Ubiquitin thioesterase 34; AltName: Full=Ubiquitin-specific-processing protease 34;+++[A0A0C4DG73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000410559}; Flags: Fragment;+++[H7BZ73_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000388129}; Flags: Fragment;+++[H7C150_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398489}; Flags: Fragment;+++[H7C183_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 34 {ECO:0000313|Ensembl:ENSP00000398960}; Flags: Fragment;"]
[9737,"'GPRASP1'",4,16,10,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0005515///protein binding","GO:0008333///endosome to lysosome transport+++GO:1990172///G protein-coupled receptor catabolic process","IPR016024///Armadillo-type fold+++IPR006911///Armadillo repeat-containing domain","[GASP1_HUMAN|Reviewed]RecName: Full=G-protein coupled receptor-associated sorting protein 1; Short=GASP-1;"]
[9738,"'CCP110'",101,128,114.5,{"$nulls":4},"GO:0005815///microtubule organizing center+++GO:0005929///cilium+++GO:0042995///cell projection+++GO:0005814///centriole+++GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding","GO:0030030///cell projection organization+++GO:0032465///regulation of cytokinesis+++GO:0007099///centriole replication+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0045724///positive regulation of cilium assembly+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:1902018///negative regulation of cilium assembly+++GO:0016579///protein deubiquitination+++GO:0051298///centrosome duplication+++GO:0032053///ciliary basal body organization","IPR033207///Centriolar coiled-coil protein of 110kDa","[CP110_HUMAN|Reviewed]RecName: Full=Centriolar coiled-coil protein of 110 kDa; AltName: Full=Centrosomal protein of 110 kDa; Short=CP110; Short=Cep110;+++[A0A024QYV8_HUMAN|Unreviewed]SubName: Full=CP110 protein, isoform CRA_a {ECO:0000313|EMBL:EAW50288.1};+++[H3BMS1_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000454514}; Flags: Fragment;+++[H3BVH3_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000458123};+++[I3L262_HUMAN|Unreviewed]SubName: Full=Centriolar coiled-coil protein of 110 kDa {ECO:0000313|Ensembl:ENSP00000459410}; Flags: Fragment;"]
[9739,"'SETD1A'",878,1128,1003,"00310///Lysine degradation",null,null,"R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine","GO:0048188///Set1C/COMPASS complex+++GO:0016607///nuclear speck+++GO:0000790///nuclear chromatin+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0016740///transferase activity+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008013///beta-catenin binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003676///nucleic acid binding+++GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0008168///methyltransferase activity+++GO:0008134///transcription factor binding","GO:1902036///regulation of hematopoietic stem cell differentiation+++GO:0032259///methylation+++GO:0045652///regulation of megakaryocyte differentiation+++GO:1902275///regulation of chromatin organization+++GO:0051568///histone H3-K4 methylation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization","IPR034467///Set1A, RNA recognition motif+++IPR024657///COMPASS complex Set1 subunit, N-SET domain+++IPR037841///Histone-lysine N-methyltransferase SETD1A+++IPR000504///RNA recognition motif domain+++IPR003616///Post-SET domain+++IPR035979///RNA-binding domain superfamily+++IPR001214///SET domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily","[SET1A_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETD1A; EC=2.1.1.43; AltName: Full=Lysine N-methyltransferase 2F; AltName: Full=SET domain-containing protein 1A; Short=hSET1A; AltName: Full=Set1/Ash2 histone methyltransferase complex subunit SET1;+++[C9J2Z9_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETD1A {ECO:0000313|Ensembl:ENSP00000391408}; Flags: Fragment;+++[L0R6N9_HUMAN|Unreviewed]SubName: Full=Alternative protein SETD1A {ECO:0000313|EMBL:CCO13810.1};"]
[9741,"'LAPTM4A'",5340,5005,5172.5,"04142///Lysosome",{"$nulls":3},"GO:0012505///endomembrane system+++GO:0016021///integral component of membrane+++GO:0031902///late endosome membrane+++GO:0016020///membrane+++GO:0005765///lysosomal membrane+++GO:0005794///Golgi apparatus","GO:0005515///protein binding",null,"IPR004687///Lysosomal-associated transmembrane protein 4/5+++IPR018396///Lysosomal-associated transmembrane protein, 4A/5","[LAP4A_HUMAN|Reviewed]RecName: Full=Lysosomal-associated transmembrane protein 4A; AltName: Full=Golgi 4-transmembrane-spanning transporter MTP;+++[Q4ZG00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAX88938.1}; Flags: Fragment;+++[Q53QZ6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein LAPTM4A {ECO:0000313|EMBL:AAY24172.1}; Flags: Fragment;+++[Q6IBP4_HUMAN|Unreviewed]SubName: Full=LAPTM4A protein {ECO:0000313|EMBL:CAG33039.1}; SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH93075.1}; SubName: Full=Lysosomal-associated protein transmembrane 4 alpha, isoform CRA_b {ECO:0000313|EMBL:EAX00834.1};+++[Q9BTU8_HUMAN|Unreviewed]SubName: Full=Lysosomal protein transmembrane 4 alpha {ECO:0000313|EMBL:AAH03158.1};"]
[9742,"'IFT140'",400,388,394,null,"H02157///Short-rib thoracic dysplasia",null,null,"GO:0005737///cytoplasm+++GO:0097730///non-motile cilium+++GO:0005929///cilium+++GO:0097542///ciliary tip+++GO:0036064///ciliary basal body+++GO:0030991///intraciliary transport particle A+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0032391///photoreceptor connecting cilium+++GO:0005930///axoneme+++GO:0001750///photoreceptor outer segment+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0003674///molecular_function","GO:0035721///intraciliary retrograde transport+++GO:0060271///cilium assembly+++GO:0061512///protein localization to cilium+++GO:1990403///embryonic brain development+++GO:0035108///limb morphogenesis+++GO:0008589///regulation of smoothened signaling pathway+++GO:0035735///intraciliary transport involved in cilium assembly+++GO:0042073///intraciliary transport+++GO:0021532///neural tube patterning+++GO:0007368///determination of left/right symmetry+++GO:1905515///non-motile cilium assembly+++GO:0048705///skeletal system morphogenesis+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0035845///photoreceptor cell outer segment organization+++GO:1902017///regulation of cilium assembly+++GO:0030030///cell projection organization+++GO:0042733///embryonic digit morphogenesis+++GO:0060041///retina development in camera-type eye+++GO:0007507///heart development+++GO:0031076///embryonic camera-type eye development+++GO:0072001///renal system development","IPR001680///WD40 repeat+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR024977///Anaphase-promoting complex subunit 4, WD40 domain+++IPR017986///WD40-repeat-containing domain+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily","[IF140_HUMAN|Reviewed]RecName: Full=Intraflagellar transport protein 140 homolog; AltName: Full=WD and tetratricopeptide repeats protein 2;+++[H3BNC5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000454781}; Flags: Fragment;+++[H3BTA5_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000457092}; Flags: Fragment;+++[I3L0Y8_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000458439}; Flags: Fragment;+++[J3KPW0_HUMAN|Unreviewed]SubName: Full=Intraflagellar transport protein 140 homolog {ECO:0000313|Ensembl:ENSP00000380562};+++[Q96RY6_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein gs114 {ECO:0000313|EMBL:AAK61287.1};"]
[9743,"'ARHGAP32'",127,190,158.5,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0010008///endosome membrane+++GO:0042995///cell projection+++GO:0005768///endosome+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0030054///cell junction+++GO:0015629///actin cytoskeleton+++GO:0005783///endoplasmic reticulum+++GO:0014069///postsynaptic density+++GO:0005789///endoplasmic reticulum membrane+++GO:0043197///dendritic spine+++GO:0045202///synapse+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0001650///fibrillar center","GO:0035091///phosphatidylinositol binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding","GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007264///small GTPase mediated signal transduction+++GO:0051056///regulation of small GTPase mediated signal transduction","IPR008936///Rho GTPase activation protein+++IPR000198///Rho GTPase-activating protein domain+++IPR036028///SH3-like domain superfamily+++IPR036871///PX domain superfamily+++IPR001683///Phox homologous domain+++IPR001452///SH3 domain","[RHG32_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 32; AltName: Full=Brain-specific Rho GTPase-activating protein; AltName: Full=GAB-associated Cdc42/Rac GTPase-activating protein; AltName: Full=GC-GAP; AltName: Full=GTPase regulator interacting with TrkA; AltName: Full=Rho-type GTPase-activating protein 32; AltName: Full=Rho/Cdc42/Rac GTPase-activating protein RICS; AltName: Full=RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling; AltName: Full=p200RhoGAP; AltName: Full=p250GAP;+++[A0A024R3K8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_c {ECO:0000313|EMBL:EAW67737.1};+++[A0A024R3N1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein, isoform CRA_a {ECO:0000313|EMBL:EAW67733.1};+++[A0A2X0SFD0_HUMAN|Unreviewed]SubName: Full=ARHGAP32 {ECO:0000313|EMBL:SPT35703.1}; Flags: Fragment;+++[E9PRH3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432303}; Flags: Fragment;+++[G3V174_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 32 {ECO:0000313|Ensembl:ENSP00000432468}; SubName: Full=Rho GTPase-activating protein, isoform CRA_b {ECO:0000313|EMBL:EAW67734.1};+++[Q86T64_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp451F1115 {ECO:0000313|EMBL:CAD89974.1}; Flags: Fragment;+++[Q86UT2_HUMAN|Unreviewed]SubName: Full=RICS protein {ECO:0000313|EMBL:AAH51236.1}; Flags: Fragment;"]
[9744,"'ACAP1'",14.8,23.39,19.095,"04144///Endocytosis",{"$nulls":3},"GO:0055038///recycling endosome membrane+++GO:0005768///endosome+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0046872///metal ion binding","GO:0043547///positive regulation of GTPase activity+++GO:0015031///protein transport","IPR020683///Ankyrin repeat-containing domain+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR001849///Pleckstrin homology domain+++IPR001164///Arf GTPase activating protein+++IPR000909///Phosphatidylinositol-specific phospholipase C, X domain+++IPR027267///AH/BAR domain superfamily+++IPR011993///PH-like domain superfamily+++IPR038508///ArfGAP domain superfamily+++IPR002110///Ankyrin repeat+++IPR037278///ARFGAP/RecO-like zinc finger","[ACAP1_HUMAN|Reviewed]RecName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1; AltName: Full=Centaurin-beta-1; Short=Cnt-b1;+++[I3L0K9_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000458173}; Flags: Fragment;+++[I3L268_HUMAN|Unreviewed]SubName: Full=Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000459422}; Flags: Fragment;"]
[9745,"'ZNF536'",152,165,158.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0044323///retinoic acid-responsive element binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific","GO:0045665///negative regulation of neuron differentiation+++GO:0048387///negative regulation of retinoic acid receptor signaling pathway+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZN536_HUMAN|Reviewed]RecName: Full=Zinc finger protein 536;+++[A7E228_HUMAN|Unreviewed]SubName: Full=ZNF536 protein {ECO:0000313|EMBL:AAI50172.1};+++[K7EJP8_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465268}; Flags: Fragment;+++[K7EKT4_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000465771}; Flags: Fragment;+++[K7EQN6_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 536 {ECO:0000313|Ensembl:ENSP00000467909}; Flags: Fragment;"]
[9746,"'CLSTN3'",4327,5027,4677,{"$nulls":4},"GO:0099061///integral component of postsynaptic density membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0045211///postsynaptic membrane+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0098982///GABA-ergic synapse+++GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0009986///cell surface+++GO:0098978///glutamatergic synapse+++GO:0014069///postsynaptic density","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0051965///positive regulation of synapse assembly+++GO:0051932///synaptic transmission, GABAergic+++GO:1905606///regulation of presynapse assembly+++GO:0001558///regulation of cell growth+++GO:0050806///positive regulation of synaptic transmission+++GO:1902474///positive regulation of protein localization to synapse+++GO:0007155///cell adhesion+++GO:0007416///synapse assembly+++GO:0035249///synaptic transmission, glutamatergic","IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR015919///Cadherin-like superfamily+++IPR026914///Calsyntenin+++IPR002126///Cadherin-like","[CSTN3_HUMAN|Reviewed]RecName: Full=Calsyntenin-3; AltName: Full=Alcadein-beta; Short=Alc-beta; Flags: Precursor;+++[F5H172_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443959}; Flags: Fragment;+++[F5H5C6_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443490}; Flags: Fragment;+++[F5H5D7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000443468}; Flags: Fragment;+++[F5H746_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442801}; Flags: Fragment;+++[F5H7C7_HUMAN|Unreviewed]SubName: Full=Calsyntenin-3 {ECO:0000313|Ensembl:ENSP00000442612}; Flags: Fragment;+++[Q8IUW6_HUMAN|Unreviewed]SubName: Full=CLSTN3 protein {ECO:0000313|EMBL:AAH39075.1};"]
[9747,"'TCAF1'",2230,2735,2482.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0005515///protein binding+++GO:0044325///ion channel binding","GO:1901529///positive regulation of anion channel activity+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0030336///negative regulation of cell migration","IPR035423///M60-like domain, N-terminal+++IPR029062///Class I glutamine amidotransferase-like+++IPR031161///Peptidase family M60 domain","[TCAF1_HUMAN|Reviewed]RecName: Full=TRPM8 channel-associated factor 1 {ECO:0000303|PubMed:25559186}; AltName: Full=TRP channel-associated factor 1 {ECO:0000303|PubMed:25559186};+++[B4DST7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58406, weakly similar to Mus musculus experimental autoimmune prostatitis antigen 2 (Eapa2), mRNA {ECO:0000313|EMBL:BAG61749.1};+++[C9J648_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000418432}; Flags: Fragment;+++[C9J9F4_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000417600}; Flags: Fragment;+++[C9JD13_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000420607}; Flags: Fragment;+++[C9K0E7_HUMAN|Unreviewed]SubName: Full=TRPM8 channel-associated factor 1 {ECO:0000313|Ensembl:ENSP00000419622}; Flags: Fragment;"]
[9748,"'SLK'",444,526,485,"04114///Oocyte meiosis",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0048471///perinuclear region of cytoplasm+++GO:0031252///cell leading edge","GO:0045296///cadherin binding+++GO:0042803///protein homodimerization activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0042802///identical protein binding","GO:0030334///regulation of cell migration+++GO:0023014///signal transduction by protein phosphorylation+++GO:0042981///regulation of apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0031122///cytoplasmic microtubule organization+++GO:0006915///apoptotic process+++GO:0051893///regulation of focal adhesion assembly+++GO:0007346///regulation of mitotic cell cycle+++GO:0032147///activation of protein kinase activity","IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR001943///UVR domain+++IPR022165///Polo kinase kinase+++IPR011009///Protein kinase-like domain superfamily+++IPR017441///Protein kinase, ATP binding site","[SLK_HUMAN|Reviewed]RecName: Full=STE20-like serine/threonine-protein kinase; Short=STE20-like kinase; Short=hSLK; EC=2.7.11.1; AltName: Full=CTCL tumor antigen se20-9; AltName: Full=STE20-related serine/threonine-protein kinase; Short=STE20-related kinase; AltName: Full=Serine/threonine-protein kinase 2;+++[L8ECF1_HUMAN|Unreviewed]SubName: Full=Alternative protein SLK {ECO:0000313|EMBL:CCQ43457.1};"]
[9749,"'PHACTR2'",376,523,449.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031092///platelet alpha granule membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0003779///actin binding+++GO:0005515///protein binding+++GO:0004864///protein phosphatase inhibitor activity","GO:0002576///platelet degranulation+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","IPR029991///Phosphatase and actin regulator 2+++IPR004018///RPEL repeat","[PHAR2_HUMAN|Reviewed]RecName: Full=Phosphatase and actin regulator 2;+++[F5H858_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[F6TH74_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113}; Flags: Fragment;+++[H9KVA6_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};+++[J3KP75_HUMAN|Unreviewed]RecName: Full=Phosphatase and actin regulator {ECO:0000256|RuleBase:RU301113};"]
[975,"'CD81'",14010,12283,13146.5,"05144///Malaria+++04662///B cell receptor signaling pathway+++05160///Hepatitis C","H00088///Common variable immunodeficiency (CVID)",null,null,"GO:0001772///immunological synapse+++GO:0031982///vesicle+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016021///integral component of membrane+++GO:0070062///extracellular exosome+++GO:0016020///membrane+++GO:0005925///focal adhesion","GO:0001618///virus receptor activity+++GO:0023026///MHC class II protein complex binding+++GO:0005515///protein binding+++GO:0005178///integrin binding+++GO:1990459///transferrin receptor binding","GO:0008284///positive regulation of cell proliferation+++GO:0046718///viral entry into host cell+++GO:0061462///protein localization to lysosome+++GO:0031647///regulation of protein stability+++GO:0050731///positive regulation of peptidyl-tyrosine phosphorylation+++GO:2000145///regulation of cell motility+++GO:0046813///receptor-mediated virion attachment to host cell+++GO:0008104///protein localization+++GO:0050776///regulation of immune response+++GO:0030449///regulation of complement activation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0000187///activation of MAPK activity+++GO:0031623///receptor internalization+++GO:0008283///cell proliferation+++GO:0016032///viral process+++GO:0071404///cellular response to low-density lipoprotein particle stimulus+++GO:0043128///positive regulation of 1-phosphatidylinositol 4-kinase activity+++GO:0030890///positive regulation of B cell proliferation+++GO:1904352///positive regulation of protein catabolic process in the vacuole+++GO:0007166///cell surface receptor signaling pathway","IPR000301///Tetraspanin+++IPR018499///Tetraspanin/Peripherin+++IPR018503///Tetraspanin, conserved site+++IPR008952///Tetraspanin, EC2 domain superfamily","[CD81_HUMAN|Reviewed]RecName: Full=CD81 antigen; AltName: Full=26 kDa cell surface protein TAPA-1; AltName: Full=Target of the antiproliferative antibody 1; AltName: Full=Tetraspanin-28; Short=Tspan-28; AltName: CD_antigen=CD81;+++[A0A024RCB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[A6NMH8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PIF1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJK1_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PM31_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000433178}; Flags: Fragment;+++[E9PPF5_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432723}; Flags: Fragment;+++[E9PQV4_HUMAN|Unreviewed]SubName: Full=CD81 antigen {ECO:0000313|Ensembl:ENSP00000432497}; Flags: Fragment;+++[E9PRJ8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDJ9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YDL9_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[H0YEE2_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;"]
[9750,"'RIPOR2'",20,17,18.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005856///cytoskeleton+++GO:0060171///stereocilium membrane+++GO:0030175///filopodium+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0016324///apical plasma membrane+++GO:0042995///cell projection+++GO:0005886///plasma membrane+++GO:0032420///stereocilium","GO:0071889///14-3-3 protein binding+++GO:0042802///identical protein binding+++GO:0005515///protein binding","GO:0071158///positive regulation of cell cycle arrest+++GO:0060088///auditory receptor cell stereocilium organization+++GO:0007605///sensory perception of sound+++GO:1903904///negative regulation of establishment of T cell polarity+++GO:0071260///cellular response to mechanical stimulus+++GO:2000405///negative regulation of T cell migration+++GO:0007162///negative regulation of cell adhesion+++GO:0051491///positive regulation of filopodium assembly+++GO:0045663///positive regulation of myoblast differentiation+++GO:0006935///chemotaxis+++GO:1905872///negative regulation of protein localization to cell leading edge+++GO:0042130///negative regulation of T cell proliferation+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:2001107///negative regulation of Rho guanyl-nucleotide exchange factor activity+++GO:0007517///muscle organ development+++GO:0007275///multicellular organism development+++GO:0007155///cell adhesion+++GO:0009968///negative regulation of signal transduction+++GO:0048741///skeletal muscle fiber development+++GO:1901741///positive regulation of myoblast fusion+++GO:2000391///positive regulation of neutrophil extravasation+++GO:0030154///cell differentiation+++GO:0045184///establishment of protein localization+++GO:2000114///regulation of establishment of cell polarity+++GO:1990869///cellular response to chemokine+++GO:0051260///protein homooligomerization+++GO:1901673///regulation of mitotic spindle assembly+++GO:0090023///positive regulation of neutrophil chemotaxis","IPR016024///Armadillo-type fold+++IPR033035///Rho family-interacting cell polarization regulator 2+++IPR026136///RIPOR family member 3+++IPR011989///Armadillo-like helical+++IPR031780///FAM65, N-terminal","[RIPR2_HUMAN|Reviewed]RecName: Full=Rho family-interacting cell polarization regulator 2;+++[A0A024QZY9_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_c {ECO:0000313|EMBL:EAW55471.1};+++[A0A024R028_HUMAN|Unreviewed]SubName: Full=Chromosome 6 open reading frame 32, isoform CRA_a {ECO:0000313|EMBL:EAW55469.1};+++[A0A2R8Y4B9_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493881}; Flags: Fragment;+++[A0A2R8Y4N2_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000493948}; Flags: Fragment;+++[A0A2R8Y7B3_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000495879};+++[A0A2R8YEE0_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494268};+++[A0A2R8YF77_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000494904};+++[B7Z5J9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56137 {ECO:0000313|EMBL:BAH12935.1};+++[B7Z6D6_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60883 {ECO:0000313|EMBL:BAH13222.1};+++[B7Z6U4_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441305}; SubName: Full=cDNA FLJ56038 {ECO:0000313|EMBL:BAH13380.1};+++[F5GX51_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000441138};+++[F5H029_HUMAN|Unreviewed]SubName: Full=Rho family-interacting cell polarization regulator 2 {ECO:0000313|Ensembl:ENSP00000438425};"]
[9751,"'SNPH'",327,327,327,{"$nulls":4},"GO:0043025///neuronal cell body+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0031966///mitochondrial membrane+++GO:0043005///neuron projection+++GO:0045202///synapse+++GO:0030054///cell junction+++GO:0005881///cytoplasmic microtubule+++GO:0042734///presynaptic membrane+++GO:0016021///integral component of membrane","GO:0017075///syntaxin-1 binding","GO:0016081///synaptic vesicle docking+++GO:0007269///neurotransmitter secretion+++GO:0030182///neuron differentiation+++GO:0007420///brain development","IPR028197///Syntaphilin/Syntabulin+++IPR026196///Syntaphilin","[SNPH_HUMAN|Reviewed]RecName: Full=Syntaphilin;"]
[9752,"'PCDHA9'",2.73,8.34,5.535,{"$nulls":4},"GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane","GO:0005509///calcium ion binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0007155///cell adhesion","IPR020894///Cadherin conserved site+++IPR002126///Cadherin-like+++IPR032455///Cadherin, cytoplasmic C-terminal domain+++IPR031904///Cadherin, C-terminal catenin-binding domain+++IPR013164///Cadherin, N-terminal+++IPR015919///Cadherin-like superfamily","[PCDA9_HUMAN|Reviewed]RecName: Full=Protocadherin alpha-9; Short=PCDH-alpha-9; Flags: Precursor;"]
[9753,"'ZSCAN12'",75.99,102.76,89.375,{"$nulls":4},"GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific","GO:0006355///regulation of transcription, DNA-templated+++GO:0006357///regulation of transcription by RNA polymerase II","IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily+++IPR038269///SCAN domain superfamily+++IPR003309///SCAN domain","[ZSC12_HUMAN|Reviewed]RecName: Full=Zinc finger and SCAN domain-containing protein 12; AltName: Full=Zinc finger protein 305; AltName: Full=Zinc finger protein 96;+++[A0A024RCI2_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 96, isoform CRA_a {ECO:0000313|EMBL:EAX03162.1};"]
[9754,"'STARD8'",6,6,6,{"$nulls":4},"GO:0005829///cytosol+++GO:0005925///focal adhesion+++GO:0030054///cell junction","GO:0005096///GTPase activator activity+++GO:0008289///lipid binding","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007165///signal transduction+++GO:0043547///positive regulation of GTPase activity","IPR002913///START domain+++IPR008936///Rho GTPase activation protein+++IPR023393///START-like domain superfamily+++IPR000198///Rho GTPase-activating protein domain","[STAR8_HUMAN|Reviewed]RecName: Full=StAR-related lipid transfer protein 8; AltName: Full=Deleted in liver cancer 3 protein; Short=DLC-3; AltName: Full=START domain-containing protein 8; Short=StARD8; AltName: Full=START-GAP3;+++[A0A2X0U2P1_HUMAN|Unreviewed]SubName: Full=STARD8 {ECO:0000313|EMBL:SPT35801.1}; Flags: Fragment;+++[E5RFN7_HUMAN|Unreviewed]SubName: Full=StAR-related lipid transfer protein 8 {ECO:0000313|Ensembl:ENSP00000428031};"]
[9755,"'TBKBP1'",579,621,600,"04622///RIG-I-like receptor signaling pathway",{"$nulls":4},"GO:0005515///protein binding","GO:0002376///immune system process+++GO:0016032///viral process+++GO:0045087///innate immune response","IPR024581///Tbk1/Ikki binding domain","[TBKB1_HUMAN|Reviewed]RecName: Full=TANK-binding kinase 1-binding protein 1; Short=TBK1-binding protein 1;+++[D3DTT5_HUMAN|Unreviewed]SubName: Full=TBK1 binding protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW94806.1};+++[F5H1U4_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000446365}; Flags: Fragment;+++[J3KS71_HUMAN|Unreviewed]SubName: Full=TANK-binding kinase 1-binding protein 1 {ECO:0000313|Ensembl:ENSP00000462339}; Flags: Fragment;"]
[9757,"'KMT2B'",799,1050,924.5,"00310///Lysine degradation","H01613///Follicular lymphoma+++H00831///Primary dystonia",null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine","GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0035097///histone methyltransferase complex","GO:0008270///zinc ion binding+++GO:0016740///transferase activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0018024///histone-lysine N-methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0005515///protein binding+++GO:0042800///histone methyltransferase activity (H3-K4 specific)+++GO:0008168///methyltransferase activity","GO:0051568///histone H3-K4 methylation+++GO:0032259///methylation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0001541///ovarian follicle development+++GO:0006355///regulation of transcription, DNA-templated+++GO:0045652///regulation of megakaryocyte differentiation+++GO:0009994///oocyte differentiation+++GO:0034968///histone lysine methylation+++GO:0006325///chromatin organization+++GO:0016458///gene silencing+++GO:0007613///memory+++GO:0080182///histone H3-K4 trimethylation+++GO:0051569///regulation of histone H3-K4 methylation+++GO:0048096///chromatin-mediated maintenance of transcription+++GO:0030728///ovulation","IPR034732///Extended PHD (ePHD) domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR019787///Zinc finger, PHD-finger+++IPR016569///Methyltransferase, trithorax+++IPR003616///Post-SET domain+++IPR001214///SET domain+++IPR001965///Zinc finger, PHD-type+++IPR036427///Bromodomain-like superfamily+++IPR003888///FY-rich, N-terminal+++IPR002857///Zinc finger, CXXC-type+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR003889///FY-rich, C-terminal","[KMT2B_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase 2B; Short=Lysine N-methyltransferase 2B; EC=2.1.1.43; AltName: Full=Myeloid/lymphoid or mixed-lineage leukemia protein 4; AltName: Full=Trithorax homolog 2; AltName: Full=WW domain-binding protein 7; Short=WBP-7;"]
[9758,"'FRMPD4'",5,3,4,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0032991///protein-containing complex+++GO:0042995///cell projection+++GO:0014069///postsynaptic density+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine","GO:0008289///lipid binding+++GO:0005546///phosphatidylinositol-4,5-bisphosphate binding+++GO:0005515///protein binding","GO:0051835///positive regulation of synapse structural plasticity+++GO:0098974///postsynaptic actin cytoskeleton organization","IPR001202///WW domain+++IPR000299///FERM domain+++IPR036034///PDZ superfamily+++IPR019749///Band 4.1 domain+++IPR035963///FERM superfamily, second domain+++IPR019748///FERM central domain+++IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR029071///Ubiquitin-like domain superfamily+++IPR011993///PH-like domain superfamily+++IPR001478///PDZ domain","[FRPD4_HUMAN|Reviewed]RecName: Full=FERM and PDZ domain-containing protein 4; AltName: Full=PDZ domain-containing protein 10; AltName: Full=PSD-95-interacting regulator of spine morphogenesis; Short=Preso;+++[A0A087WYX8_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000482182};+++[A0A1W2PQW0_HUMAN|Unreviewed]SubName: Full=FERM and PDZ domain-containing protein 4 {ECO:0000313|Ensembl:ENSP00000492353}; Flags: Fragment;+++[B7ZLE1_HUMAN|Unreviewed]SubName: Full=FRMPD4 protein {ECO:0000313|EMBL:AAI43747.1};"]
[9759,"'HDAC4'",58.9,121,89.95,"05203///Viral carcinogenesis+++05034///Alcoholism+++05169///Epstein-Barr virus infection+++05165///Human papillomavirus infection+++04371///Apelin signaling pathway","H00561///Brachydactyly-mental retardation syndrome",null,null,"GO:0017053///transcriptional repressor complex+++GO:0005654///nucleoplasm+++GO:0042641///actomyosin+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0000118///histone deacetylase complex+++GO:0031672///A band+++GO:0030018///Z disc+++GO:0031594///neuromuscular junction+++GO:0030017///sarcomere+++GO:0005829///cytosol+++GO:0005634///nucleus","GO:0008134///transcription factor binding+++GO:1990841///promoter-specific chromatin binding+++GO:0004407///histone deacetylase activity+++GO:0042826///histone deacetylase binding+++GO:0032041///NAD-dependent histone deacetylase activity (H3-K14 specific)+++GO:0033613///activating transcription factor binding+++GO:0019789///SUMO transferase activity+++GO:0044212///transcription regulatory region DNA binding+++GO:0008270///zinc ion binding+++GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0030955///potassium ion binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046872///metal ion binding+++GO:0003714///transcription corepressor activity+++GO:0070491///repressing transcription factor binding+++GO:0033558///protein deacetylase activity+++GO:0005515///protein binding+++GO:0001085///RNA polymerase II transcription factor binding","GO:0006954///inflammatory response+++GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0040029///regulation of gene expression, epigenetic+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0014898///cardiac muscle hypertrophy in response to stress+++GO:0033235///positive regulation of protein sumoylation+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0030183///B cell differentiation+++GO:0006338///chromatin remodeling+++GO:0045668///negative regulation of osteoblast differentiation+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0042493///response to drug+++GO:0034983///peptidyl-lysine deacetylation+++GO:0070555///response to interleukin-1+++GO:0008284///positive regulation of cell proliferation+++GO:0001501///skeletal system development+++GO:0048661///positive regulation of smooth muscle cell proliferation+++GO:0002076///osteoblast development+++GO:0006476///protein deacetylation+++GO:0014911///positive regulation of smooth muscle cell migration+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0071374///cellular response to parathyroid hormone stimulus+++GO:0014894///response to denervation involved in regulation of muscle adaptation+++GO:0048742///regulation of skeletal muscle fiber development+++GO:0051153///regulation of striated muscle cell differentiation+++GO:0042113///B cell activation+++GO:1902894///negative regulation of pri-miRNA transcription by RNA polymerase II+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:1903428///positive regulation of reactive oxygen species biosynthetic process+++GO:0007399///nervous system development+++GO:0045820///negative regulation of glycolytic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0016925///protein sumoylation+++GO:0070932///histone H3 deacetylation+++GO:0043393///regulation of protein binding+++GO:0010882///regulation of cardiac muscle contraction by calcium ion signaling+++GO:0008285///negative regulation of cell proliferation+++GO:0071356///cellular response to tumor necrosis factor+++GO:0016575///histone deacetylation+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0070933///histone H4 deacetylation+++GO:0006325///chromatin organization+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0010832///negative regulation of myotube differentiation","IPR017320///Histone deacetylase class II, eukaryotic+++IPR033660///Histone deacetylase 4+++IPR023801///Histone deacetylase domain+++IPR023696///Ureohydrolase domain superfamily+++IPR024643///Histone deacetylase, glutamine rich N-terminal domain+++IPR000286///Histone deacetylase family+++IPR037138///Histone deacetylase domain superfamily","[HDAC4_HUMAN|Reviewed]RecName: Full=Histone deacetylase 4; Short=HD4; EC=3.5.1.98;+++[C9J0X4_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000392912}; Flags: Fragment;+++[C9J481_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000405226}; Flags: Fragment;+++[F5H0B1_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000438111}; Flags: Fragment;+++[H7BZT3_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000391226}; Flags: Fragment;+++[H7C397_HUMAN|Unreviewed]SubName: Full=Histone deacetylase 4 {ECO:0000313|Ensembl:ENSP00000410551}; Flags: Fragment;"]
[976,"'ADGRE5'",250.99,152.78,201.885,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005615///extracellular space+++GO:0070062///extracellular exosome+++GO:0005887///integral component of plasma membrane+++GO:0005925///focal adhesion+++GO:0030667///secretory granule membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0004930///G protein-coupled receptor activity+++GO:0005515///protein binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005509///calcium ion binding","GO:0007267///cell-cell signaling+++GO:0007155///cell adhesion+++GO:0007189///adenylate cyclase-activating G protein-coupled receptor signaling pathway+++GO:0006955///immune response+++GO:0007166///cell surface receptor signaling pathway+++GO:0006954///inflammatory response+++GO:0043312///neutrophil degranulation+++GO:0007165///signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","IPR001881///EGF-like calcium-binding domain+++IPR018097///EGF-like calcium-binding, conserved site+++IPR017983///GPCR, family 2, secretin-like, conserved site+++IPR000152///EGF-type aspartate/asparagine hydroxylation site+++IPR017981///GPCR, family 2-like+++IPR000742///EGF-like domain+++IPR003056///GPCR, family 2, CD97 antigen+++IPR000203///GPS motif+++IPR009030///Growth factor receptor cysteine-rich domain superfamily+++IPR000832///GPCR, family 2, secretin-like","[CD97_HUMAN|Reviewed]RecName: Full=CD97 antigen; AltName: Full=Leukocyte antigen CD97; AltName: CD_antigen=CD97; Contains: RecName: Full=CD97 antigen subunit alpha; Contains: RecName: Full=CD97 antigen subunit beta; Flags: Precursor;+++[K7EKV5_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000465800}; Flags: Fragment;+++[K7EPE8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467351}; Flags: Fragment;+++[K7EPP8_HUMAN|Unreviewed]SubName: Full=Adhesion G protein-coupled receptor E5 {ECO:0000313|Ensembl:ENSP00000467478}; Flags: Fragment;"]
[9760,"'TOX'",498,604,551,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding","GO:0048535///lymph node development+++GO:0032825///positive regulation of natural killer cell differentiation+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0030098///lymphocyte differentiation+++GO:0048541///Peyer's patch development","IPR009071///High mobility group box domain+++IPR036910///High mobility group box domain superfamily","[TOX_HUMAN|Reviewed]RecName: Full=Thymocyte selection-associated high mobility group box protein TOX; AltName: Full=Thymus high mobility group box protein TOX;"]
[9761,"'MLEC'",3358,4179,3768.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0035579///specific granule membrane+++GO:0005886///plasma membrane","GO:0019899///enzyme binding+++GO:0030246///carbohydrate binding","GO:0005975///carbohydrate metabolic process+++GO:0043312///neutrophil degranulation+++GO:0006457///protein folding","IPR039155///Malectin+++IPR021720///Malectin domain","[MLEC_HUMAN|Reviewed]RecName: Full=Malectin; Flags: Precursor;+++[F5GX14_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000440746};+++[F5H1S8_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000438950}; Flags: Fragment;+++[H0YG07_HUMAN|Unreviewed]SubName: Full=Malectin {ECO:0000313|Ensembl:ENSP00000441247}; Flags: Fragment;"]
[9762,"'LZTS3'",604,510,557,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0030054///cell junction+++GO:0045202///synapse+++GO:0005886///plasma membrane+++GO:0005856///cytoskeleton+++GO:0045211///postsynaptic membrane+++GO:0014069///postsynaptic density",null,"GO:0061001///regulation of dendritic spine morphogenesis","IPR033295///Leucine zipper putative tumour suppressor 3","[LZTS3_HUMAN|Reviewed]RecName: Full=Leucine zipper putative tumor suppressor 3 {ECO:0000305}; AltName: Full=ProSAP-interacting protein 1 {ECO:0000250|UniProtKB:Q8K1Q4}; Short=ProSAPiP1 {ECO:0000250|UniProtKB:Q8K1Q4};"]
[9764,"'KIAA0513'",235.07,293,264.035,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm",null,null,"IPR039872///Uncharacterized protein KIAA0513","[K0513_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0513;+++[H3BMU3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454547}; Flags: Fragment;+++[H3BNA7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0513 {ECO:0000313|Ensembl:ENSP00000454758}; Flags: Fragment;"]
[9765,"'ZFYVE16'",97,172,134.5,"04350///TGF-beta signaling pathway+++04144///Endocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005829///cytosol+++GO:0031901///early endosome membrane+++GO:0005737///cytoplasm","GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0008565///protein transporter activity+++GO:0046872///metal ion binding+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding","GO:0016050///vesicle organization+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0030509///BMP signaling pathway+++GO:0016197///endosomal transport+++GO:0006622///protein targeting to lysosome","IPR000306///FYVE zinc finger+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR017455///Zinc finger, FYVE-related+++IPR022557///Domain of unknown function DUF3480+++IPR017165///Zinc finger FYVE domain-containing protein, endofin+++IPR035438///Zinc finger FYVE domain containing protein, SARA/endofin+++IPR011011///Zinc finger, FYVE/PHD-type","[ZFY16_HUMAN|Reviewed]RecName: Full=Zinc finger FYVE domain-containing protein 16; AltName: Full=Endofin; AltName: Full=Endosome-associated FYVE domain protein;+++[A0A024RAL3_HUMAN|Unreviewed]RecName: Full=Zinc finger FYVE domain-containing protein {ECO:0000256|PIRNR:PIRNR037289};+++[D6RC80_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000422356}; Flags: Fragment;+++[H0Y8R0_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000421785}; Flags: Fragment;+++[H0YAA4_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426500}; Flags: Fragment;+++[H0YAB1_HUMAN|Unreviewed]SubName: Full=Zinc finger FYVE domain-containing protein 16 {ECO:0000313|Ensembl:ENSP00000426536}; Flags: Fragment;"]
[9766,"'SUSD6'",475,652,563.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005575///cellular_component+++GO:0016020///membrane","GO:0003674///molecular_function+++GO:0005515///protein binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0008219///cell death","IPR035976///Sushi/SCR/CCP superfamily+++IPR000436///Sushi/SCR/CCP domain","[SUSD6_HUMAN|Reviewed]RecName: Full=Sushi domain-containing protein 6 {ECO:0000312|HGNC:HGNC:19956}; AltName: Full=Drug-activated gene overexpressed protein {ECO:0000303|PubMed:24652652}; Flags: Precursor;"]
[9767,"'JADE3'",58,92,75,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0000123///histone acetyltransferase complex","GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0043981///histone H4-K5 acetylation+++GO:0043966///histone H3 acetylation+++GO:0043983///histone H4-K12 acetylation+++GO:0043984///histone H4-K16 acetylation+++GO:0043982///histone H4-K8 acetylation","IPR039550///JADE3, PHD domain+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR019787///Zinc finger, PHD-finger+++IPR034732///Extended PHD (ePHD) domain+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR019542///Enhancer of polycomb-like, N-terminal+++IPR019786///Zinc finger, PHD-type, conserved site+++IPR001965///Zinc finger, PHD-type","[JADE3_HUMAN|Reviewed]RecName: Full=Protein Jade-3; AltName: Full=Jade family PHD finger protein 3; AltName: Full=PHD finger protein 16;+++[A0A024R1A2_HUMAN|Unreviewed]SubName: Full=PHD finger protein 16, isoform CRA_a {ECO:0000313|EMBL:EAW59278.1};+++[F2Z2B6_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000400584}; Flags: Fragment;+++[F2Z3N8_HUMAN|Unreviewed]SubName: Full=Protein Jade-3 {ECO:0000313|Ensembl:ENSP00000391009}; Flags: Fragment;"]
[9768,"'PCLAF'",2.96,0.25,1.605,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0003682///chromatin binding","GO:0006260///DNA replication+++GO:0051726///regulation of cell cycle+++GO:0006974///cellular response to DNA damage stimulus+++GO:0009411///response to UV+++GO:0007098///centrosome cycle+++GO:0006281///DNA repair+++GO:0019985///translesion synthesis","IPR031444///PCNA-associated factor","[PAF15_HUMAN|Reviewed]RecName: Full=PCNA-associated factor {ECO:0000305}; AltName: Full=Hepatitis C virus NS5A-transactivated protein 9; Short=HCV NS5A-transactivated protein 9; AltName: Full=Overexpressed in anaplastic thyroid carcinoma 1; Short=OEATC-1; AltName: Full=PCNA-associated factor of 15 kDa; Short=PAF15; Short=p15PAF; AltName: Full=PCNA-clamp-associated factor {ECO:0000312|HGNC:HGNC:28961};+++[G9G6C4_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89543.1}; Flags: Fragment;+++[G9G6D7_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89556.1}; Flags: Fragment;+++[G9G6H1_HUMAN|Unreviewed]SubName: Full=KIAA0101 {ECO:0000313|EMBL:AEW89590.1}; Flags: Fragment;+++[H0YKX3_HUMAN|Unreviewed]SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000452975};+++[H0YMA4_HUMAN|Unreviewed]SubName: Full=HCG2039386, isoform CRA_b {ECO:0000313|EMBL:EAW77680.1}; SubName: Full=PCNA-associated factor {ECO:0000313|Ensembl:ENSP00000453527};"]
[977,"'CD151'",18730,15393,17061.5,null,"H00928///Nephropathy with pretibial epidermolysis bullosa and deafness",null,null,"GO:0009986///cell surface+++GO:0005925///focal adhesion+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005604///basement membrane+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005178///integrin binding","GO:0044319///wound healing, spreading of cells+++GO:0007155///cell adhesion+++GO:0007166///cell surface receptor signaling pathway+++GO:0031581///hemidesmosome assembly+++GO:0016477///cell migration+++GO:0045807///positive regulation of endocytosis+++GO:0030335///positive regulation of cell migration+++GO:0042098///T cell proliferation","IPR018503///Tetraspanin, conserved site+++IPR000301///Tetraspanin+++IPR008952///Tetraspanin, EC2 domain superfamily+++IPR018499///Tetraspanin/Peripherin","[CD151_HUMAN|Reviewed]RecName: Full=CD151 antigen; AltName: Full=GP27; AltName: Full=Membrane glycoprotein SFA-1; AltName: Full=Platelet-endothelial tetraspan antigen 3; Short=PETA-3; AltName: Full=Tetraspanin-24; Short=Tspan-24; AltName: CD_antigen=CD151;+++[A0A024RCB3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PJC8_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PJE8_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000433752}; Flags: Fragment;+++[E9PK37_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000431671}; Flags: Fragment;+++[E9PLZ6_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PMR4_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};+++[E9PP93_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000434663}; Flags: Fragment;+++[E9PRJ3_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[E9PSA1_HUMAN|Unreviewed]SubName: Full=CD151 antigen {ECO:0000313|Ensembl:ENSP00000435854}; Flags: Fragment;+++[K4DIA7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[K4DIB7_HUMAN|Unreviewed]RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218}; Flags: Fragment;+++[Q6ZNZ0_HUMAN|Unreviewed]SubName: Full=CD151 antigen (Raph blood group), isoform CRA_b {ECO:0000313|EMBL:EAX02401.1}; SubName: Full=cDNA FLJ26859 fis, clone PRS08290 {ECO:0000313|EMBL:BAC85335.1};"]
[9770,"'RASSF2'",863,950,906.5,"04391///Hippo signaling pathway - fly+++04392///Hippo signaling pathway - multiple species",{"$nulls":3},"GO:0000776///kinetochore+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0005794///Golgi apparatus+++GO:0000775///chromosome, centromeric region+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0000777///condensed chromosome kinetochore","GO:0004672///protein kinase activity+++GO:0005515///protein binding","GO:0038168///epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade+++GO:0001501///skeletal system development+++GO:0042981///regulation of apoptotic process+++GO:0046849///bone remodeling+++GO:0045670///regulation of osteoclast differentiation+++GO:0001503///ossification+++GO:0050821///protein stabilization+++GO:0046330///positive regulation of JNK cascade+++GO:0007049///cell cycle+++GO:0033137///negative regulation of peptidyl-serine phosphorylation+++GO:1901222///regulation of NIK/NF-kappaB signaling+++GO:0048872///homeostasis of number of cells+++GO:0006468///protein phosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:1901223///negative regulation of NIK/NF-kappaB signaling+++GO:0031954///positive regulation of protein autophosphorylation+++GO:0045667///regulation of osteoblast differentiation+++GO:0007165///signal transduction+++GO:0043065///positive regulation of apoptotic process","IPR029071///Ubiquitin-like domain superfamily+++IPR011524///SARAH domain+++IPR033618///Ras association domain-containing protein 2+++IPR033614///C-terminal RASSF family+++IPR000159///Ras-associating (RA) domain","[RASF2_HUMAN|Reviewed]RecName: Full=Ras association domain-containing protein 2;"]
[9771,"'RAPGEF5'",7,16,11.5,"04015///Rap1 signaling pathway+++04014///Ras signaling pathway",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0016604///nuclear body+++GO:0005634///nucleus","GO:0030742///GTP-dependent protein binding+++GO:0005088///Ras guanyl-nucleotide exchange factor activity+++GO:0017034///Rap guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0035556///intracellular signal transduction+++GO:0007399///nervous system development+++GO:0007264///small GTPase mediated signal transduction","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036964///Ras guanine-nucleotide exchange factor catalytic domain superfamily+++IPR029071///Ubiquitin-like domain superfamily+++IPR023578///Ras guanine nucleotide exchange factor domain superfamily+++IPR001895///Ras guanine-nucleotide exchange factors catalytic domain+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR008937///Ras-like guanine nucleotide exchange factor+++IPR000651///Ras-like guanine nucleotide exchange factor, N-terminal+++IPR019804///Ras guanine-nucleotide exchange factor, conserved site","[RPGF5_HUMAN|Reviewed]RecName: Full=Rap guanine nucleotide exchange factor 5; AltName: Full=Guanine nucleotide exchange factor for Rap1; AltName: Full=M-Ras-regulated Rap GEF; Short=MR-GEF; AltName: Full=Related to Epac; Short=Repac;+++[A0A0S2Z561_HUMAN|Unreviewed]SubName: Full=HCG38228, isoform CRA_b {ECO:0000313|EMBL:EAW93746.1}; SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 2 {ECO:0000313|EMBL:ALQ33949.1}; Flags: Fragment;+++[A0A0S2Z5S1_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 isoform 1 {ECO:0000313|EMBL:ALQ33948.1}; Flags: Fragment;+++[A8MQ07_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000343656};+++[C9JBS6_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000415664}; Flags: Fragment;+++[C9JHM4_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000395729}; Flags: Fragment;+++[E9PGY3_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000384870};+++[F8WD32_HUMAN|Unreviewed]SubName: Full=Rap guanine nucleotide exchange factor 5 {ECO:0000313|Ensembl:ENSP00000403956};+++[Q5JPD2_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp667A016 {ECO:0000313|EMBL:CAI46177.1};"]
[9772,"'TMEM94'",1117,1374,1245.5,{"$nulls":4},"GO:0016020///membrane+++GO:0016021///integral component of membrane",null,null,"IPR023298///P-type ATPase, transmembrane domain superfamily+++IPR039720///Transmembrane protein 94+++IPR006068///Cation-transporting P-type ATPase, C-terminal","[TMM94_HUMAN|Reviewed]RecName: Full=Transmembrane protein 94 {ECO:0000312|HGNC:HGNC:28983};+++[A0A024R8S6_HUMAN|Unreviewed]SubName: Full=KIAA0195, isoform CRA_a {ECO:0000313|EMBL:EAW89275.1};+++[B7Z9U5_HUMAN|Unreviewed]SubName: Full=cDNA, FLJ78959, highly similar to Transmembrane protein 94 {ECO:0000313|EMBL:BAH14431.1};+++[C9JL75_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000364397};+++[J3KRN3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462084}; Flags: Fragment;+++[J3KRU7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462170}; Flags: Fragment;+++[J3KS76_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462344};+++[J3KT63_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000462821}; Flags: Fragment;+++[J3KTL5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463046}; Flags: Fragment;+++[J3QLC5_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463487}; Flags: Fragment;+++[J3QLM7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463620}; Flags: Fragment;+++[J3QQW3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000463929};+++[J3QRT3_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464370}; Flags: Fragment;+++[J3QRT7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464375}; Flags: Fragment;+++[J3QRY7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464437}; Flags: Fragment;+++[J3QS17_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464479}; Flags: Fragment;+++[J3QS24_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464491}; Flags: Fragment;+++[J3QSG7_HUMAN|Unreviewed]SubName: Full=Transmembrane protein 94 {ECO:0000313|Ensembl:ENSP00000464679}; Flags: Fragment;"]
[9774,"'BCLAF1'",1257,1486,1371.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003677///DNA binding","GO:1990830///cellular response to leukemia inhibitory factor+++GO:0043620///regulation of DNA-templated transcription in response to stress+++GO:0043065///positive regulation of apoptotic process+++GO:2001244///positive regulation of intrinsic apoptotic signaling pathway+++GO:2000144///positive regulation of DNA-templated transcription, initiation+++GO:0006915///apoptotic process+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:2001022///positive regulation of response to DNA damage stimulus","IPR029199///THRAP3/BCLAF1 family+++IPR026668///Bcl-2-associated transcription factor 1+++IPR018545///Btz domain","[BCLF1_HUMAN|Reviewed]RecName: Full=Bcl-2-associated transcription factor 1; Short=Btf; AltName: Full=BCLAF1 and THRAP3 family member 1;+++[A0A1W2PQ43_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000491530};+++[E9PJA7_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433822};+++[E9PK09_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000431734}; Flags: Fragment;+++[E9PK91_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000435441};+++[E9PKI6_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000433505};+++[E9PQN2_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436142};+++[H0YF00_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000436913}; Flags: Fragment;+++[H0YF14_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437018}; Flags: Fragment;+++[H0YF63_HUMAN|Unreviewed]SubName: Full=Bcl-2-associated transcription factor 1 {ECO:0000313|Ensembl:ENSP00000437333}; Flags: Fragment;+++[Q6DCA8_HUMAN|Unreviewed]SubName: Full=BCLAF1 protein {ECO:0000313|EMBL:AAH78160.1}; Flags: Fragment;"]
[9775,"'EIF4A3'",487,301,394,"03013///RNA transport+++03015///mRNA surveillance pathway+++03040///Spliceosome",null,"M00430///Exon junction complex (EJC)",null,"GO:0016607///nuclear speck+++GO:1990904///ribonucleoprotein complex+++GO:0043025///neuronal cell body+++GO:0071013///catalytic step 2 spliceosome+++GO:0099524///postsynaptic cytosol+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0098978///glutamatergic synapse+++GO:0005829///cytosol+++GO:0035145///exon-exon junction complex+++GO:0005681///spliceosomal complex+++GO:0030425///dendrite+++GO:0005634///nucleus","GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0004004///ATP-dependent RNA helicase activity+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0008143///poly(A) binding+++GO:0003729///mRNA binding+++GO:0035613///RNA stem-loop binding+++GO:0035368///selenocysteine insertion sequence binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0003676///nucleic acid binding+++GO:0045182///translation regulator activity+++GO:0000166///nucleotide binding","GO:0006364///rRNA processing+++GO:0006417///regulation of translation+++GO:0017148///negative regulation of translation+++GO:0099578///regulation of translation at postsynapse, modulating synaptic transmission+++GO:0090394///negative regulation of excitatory postsynaptic potential+++GO:0072715///cellular response to selenite ion+++GO:0035640///exploration behavior+++GO:1902415///regulation of mRNA binding+++GO:0045727///positive regulation of translation+++GO:1904570///negative regulation of selenocysteine incorporation+++GO:0008306///associative learning+++GO:0006406///mRNA export from nucleus+++GO:1990416///cellular response to brain-derived neurotrophic factor stimulus+++GO:1904574///negative regulation of selenocysteine insertion sequence binding+++GO:0048701///embryonic cranial skeleton morphogenesis+++GO:0008380///RNA splicing+++GO:0031124///mRNA 3'-end processing+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0014070///response to organic cyclic compound+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0010629///negative regulation of gene expression+++GO:0051028///mRNA transport","IPR011545///DEAD/DEAH box helicase domain+++IPR000629///ATP-dependent RNA helicase DEAD-box, conserved site+++IPR014014///RNA helicase, DEAD-box type, Q motif+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR001650///Helicase, C-terminal","[IF4A3_HUMAN|Reviewed]RecName: Full=Eukaryotic initiation factor 4A-III; Short=eIF-4A-III; Short=eIF4A-III; EC=3.6.4.13 {ECO:0000269|PubMed:16170325, ECO:0000269|PubMed:17375189, ECO:0000269|PubMed:22961380}; AltName: Full=ATP-dependent RNA helicase DDX48; AltName: Full=ATP-dependent RNA helicase eIF4A-3; AltName: Full=DEAD box protein 48; AltName: Full=Eukaryotic initiation factor 4A-like NUK-34; AltName: Full=Eukaryotic translation initiation factor 4A isoform 3; AltName: Full=Nuclear matrix protein 265; Short=NMP 265; Short=hNMP 265; Contains: RecName: Full=Eukaryotic initiation factor 4A-III, N-terminally processed;+++[A0A024R8W0_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 48, isoform CRA_a {ECO:0000313|EMBL:EAW89585.1};+++[I3L3H2_HUMAN|Unreviewed]SubName: Full=Eukaryotic initiation factor 4A-III {ECO:0000313|Ensembl:ENSP00000460439}; Flags: Fragment;"]
[9776,"'ATG13'",2551,2556,2553.5,"04138///Autophagy - yeast+++04136///Autophagy - other+++04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0000407///phagophore assembly site+++GO:0005737///cytoplasm+++GO:0019898///extrinsic component of membrane+++GO:0005739///mitochondrion+++GO:0005789///endoplasmic reticulum membrane","GO:0019887///protein kinase regulator activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:1903955///positive regulation of protein targeting to mitochondrion+++GO:0098780///response to mitochondrial depolarisation+++GO:0000422///autophagy of mitochondrion+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0000045///autophagosome assembly+++GO:0016241///regulation of macroautophagy+++GO:0006914///autophagy+++GO:0000423///mitophagy+++GO:0034497///protein localization to phagophore assembly site+++GO:0032147///activation of protein kinase activity+++GO:0016236///macroautophagy","IPR036570///HORMA domain superfamily+++IPR018731///Autophagy-related protein 13, N-terminal","[ATG13_HUMAN|Reviewed]RecName: Full=Autophagy-related protein 13;+++[A0A1B0GXJ3_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463808}; Flags: Fragment;+++[A8K0S6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214};+++[E9PPR2_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;+++[H0YCL5_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000431877}; Flags: Fragment;+++[H0YDR0_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000434125}; Flags: Fragment;+++[H0YEM7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000436174}; Flags: Fragment;+++[H0YF43_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000437191}; Flags: Fragment;+++[J3KRU6_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462167}; Flags: Fragment;+++[J3KST9_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000462644}; Flags: Fragment;+++[J3QLH7_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463550}; Flags: Fragment;+++[J3QR16_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000463998}; Flags: Fragment;+++[J3QR83_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464091}; Flags: Fragment;+++[J3QRL1_HUMAN|Unreviewed]SubName: Full=Autophagy-related protein 13 {ECO:0000313|Ensembl:ENSP00000464274}; Flags: Fragment;+++[J9JIF6_HUMAN|Unreviewed]RecName: Full=Autophagy-related protein 13 {ECO:0000256|RuleBase:RU361214}; Flags: Fragment;"]
[9777,"'TM9SF4'",2180,2349,2264.5,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04062///Chemokine signaling pathway+++05167///Kaposi's sarcoma-associated herpesvirus infection+++04666///Fc gamma R-mediated phagocytosis",{"$nulls":3},"GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus+++GO:0005768///endosome+++GO:0005769///early endosome","GO:0005515///protein binding","GO:0006909///phagocytosis+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0072657///protein localization to membrane+++GO:0070072///vacuolar proton-transporting V-type ATPase complex assembly+++GO:0051453///regulation of intracellular pH+++GO:0007155///cell adhesion+++GO:0001666///response to hypoxia","IPR004240///Nonaspanin (TM9SF)","[TM9S4_HUMAN|Reviewed]RecName: Full=Transmembrane 9 superfamily member 4; AltName: Full=Tumor cannibalism associated protein 1 {ECO:0000303|PubMed:19893578}; Flags: Precursor;+++[A0A024QYR3_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[A0A0C4DFM1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[B4DH88_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F2Z2L1_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};+++[F8WCN2_HUMAN|Unreviewed]RecName: Full=Transmembrane 9 superfamily member {ECO:0000256|RuleBase:RU363079};"]
[9778,"'KIAA0232'",414,473,443.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":4},"GO:0000166///nucleotide binding+++GO:0005524///ATP binding",null,"IPR027871///Protein of unknown function DUF4603","[K0232_HUMAN|Reviewed]RecName: Full=Uncharacterized protein KIAA0232;+++[A5YKK5_HUMAN|Unreviewed]SubName: Full=KIAA0232 {ECO:0000313|EMBL:ABQ66267.1};+++[D6REK0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein KIAA0232 {ECO:0000313|Ensembl:ENSP00000426815};+++[Q9Y349_HUMAN|Unreviewed]SubName: Full=KIAA0232 protein {ECO:0000313|EMBL:CAG33441.1};"]
[9779,"'TBC1D5'",319,390,354.5,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0030904///retromer complex+++GO:0010008///endosome membrane+++GO:0005768///endosome+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0016020///membrane+++GO:0030122///AP-2 adaptor complex+++GO:0005776///autophagosome+++GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle","GO:0005515///protein binding+++GO:0035612///AP-2 adaptor complex binding+++GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity+++GO:1905394///retromer complex binding","GO:0006886///intracellular protein transport+++GO:0016236///macroautophagy+++GO:1902017///regulation of cilium assembly+++GO:0002092///positive regulation of receptor internalization+++GO:0015031///protein transport+++GO:0042147///retrograde transport, endosome to Golgi+++GO:0006914///autophagy+++GO:0090630///activation of GTPase activity+++GO:0042594///response to starvation","IPR035969///Rab-GTPase-TBC domain superfamily+++IPR000195///Rab-GTPase-TBC domain","[TBCD5_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 5;+++[A0A024R2H0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_a {ECO:0000313|EMBL:EAW64287.1};+++[A0A024R2J9_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5, isoform CRA_b {ECO:0000313|EMBL:EAW64288.1};+++[B9A6K1_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 5 {ECO:0000313|EMBL:BAH16629.1};+++[C9J397_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000410596}; Flags: Fragment;+++[C9J3F6_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411925};+++[C9JDR8_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396239}; Flags: Fragment;+++[C9JED7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000415379}; Flags: Fragment;+++[C9JIU4_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000396850}; Flags: Fragment;+++[C9JMP7_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000408603}; Flags: Fragment;+++[C9JNM0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000414159}; Flags: Fragment;+++[C9JW04_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000387395}; Flags: Fragment;+++[C9JWX0_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000399967}; Flags: Fragment;+++[C9K0P2_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000393882}; Flags: Fragment;+++[F2Z3C3_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000424998}; Flags: Fragment;+++[F2Z3I5_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 5 {ECO:0000313|Ensembl:ENSP00000411780};"]
[978,"'CDA'",27,21,24,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00983///Drug metabolism - other enzymes",null,null,"R08221///5'-deoxy-5-fluorocytidine aminohydrolase   5'-Deoxy-5-fluorocytidine + H2O <=> 5'-Deoxy-5-fluorouridine + Ammonia+++R02485///deoxycytidine aminohydrolase   Deoxycytidine + H2O <=> Deoxyuridine + Ammonia+++R01878///Cytidine aminohydrolase   Cytidine + H2O <=> Uridine + Ammonia","GO:1904813///ficolin-1-rich granule lumen+++GO:0005829///cytosol+++GO:0005576///extracellular region+++GO:0034774///secretory granule lumen+++GO:1904724///tertiary granule lumen","GO:0008270///zinc ion binding+++GO:0004126///cytidine deaminase activity+++GO:0042803///protein homodimerization activity+++GO:0003824///catalytic activity+++GO:0001882///nucleoside binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity","GO:0043097///pyrimidine nucleoside salvage+++GO:0030308///negative regulation of cell growth+++GO:0045980///negative regulation of nucleotide metabolic process+++GO:0008655///pyrimidine-containing compound salvage+++GO:0043312///neutrophil degranulation+++GO:0019858///cytosine metabolic process+++GO:0009972///cytidine deamination+++GO:0051289///protein homotetramerization+++GO:0007166///cell surface receptor signaling pathway","IPR013171///Cytidine/deoxycytidylate deaminase, zinc-binding domain+++IPR006262///Cytidine deaminase, homotetrameric+++IPR016193///Cytidine deaminase-like+++IPR016192///APOBEC/CMP deaminase, zinc-binding+++IPR002125///Cytidine and deoxycytidylate deaminase domain","[CDD_HUMAN|Reviewed]RecName: Full=Cytidine deaminase; EC=3.5.4.5; AltName: Full=Cytidine aminohydrolase;+++[Q71UE9_HUMAN|Unreviewed]SubName: Full=Cytidine deaminase {ECO:0000313|EMBL:AAC69599.1}; EC=3.5.4.5 {ECO:0000313|EMBL:AAC69599.1}; Flags: Fragment;"]
[9780,"'PIEZO1'",6288,8219,7253.5,null,"H01978///Dehydrated hereditary stomatocytosis+++H02001///Familial pseudohyperkalemia+++H00811///Distal arthrogryposis (DA)+++H00232///Hereditary stomatocytosis (HSt)",null,null,"GO:0042995///cell projection+++GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0031258///lamellipodium membrane+++GO:0033116///endoplasmic reticulum-Golgi intermediate compartment membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005886///plasma membrane","GO:0008381///mechanosensitive ion channel activity+++GO:0005261///cation channel activity","GO:0033625///positive regulation of integrin activation+++GO:0033634///positive regulation of cell-cell adhesion mediated by integrin+++GO:0042391///regulation of membrane potential+++GO:0006811///ion transport+++GO:0034220///ion transmembrane transport+++GO:0050982///detection of mechanical stimulus+++GO:0006812///cation transport+++GO:0098655///cation transmembrane transport+++GO:0055085///transmembrane transport+++GO:0071260///cellular response to mechanical stimulus","IPR031805///Piezo domain+++IPR031334///Piezo non-specific cation channel, R-Ras-binding domain+++IPR027272///Piezo family","[PIEZ1_HUMAN|Reviewed]RecName: Full=Piezo-type mechanosensitive ion channel component 1; AltName: Full=Membrane protein induced by beta-amyloid treatment; Short=Mib; AltName: Full=Protein FAM38A;+++[E7EUT2_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000333704};+++[H0YB49_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000428673}; Flags: Fragment;+++[H3BRR7_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456373}; Flags: Fragment;+++[H3BSF6_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000456680}; Flags: Fragment;+++[H7C2J5_HUMAN|Unreviewed]SubName: Full=Piezo-type mechanosensitive ion channel component 1 {ECO:0000313|Ensembl:ENSP00000406358}; Flags: Fragment;+++[M4QHP2_HUMAN|Unreviewed]RecName: Full=Piezo-type mechanosensitive ion channel component {ECO:0000256|RuleBase:RU362023};+++[Q96HU3_HUMAN|Unreviewed]SubName: Full=FAM38A protein {ECO:0000313|EMBL:AAH08073.2};"]
[9781,"'RNF144A'",45,47,46,{"$nulls":4},"GO:0000151///ubiquitin ligase complex+++GO:0031410///cytoplasmic vesicle+++GO:0016021///integral component of membrane+++GO:0030659///cytoplasmic vesicle membrane+++GO:0010008///endosome membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0046872///metal ion binding","GO:0000209///protein polyubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination","IPR002867///IBR domain+++IPR031127///E3 ubiquitin ligase RBR family+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR017907///Zinc finger, RING-type, conserved site+++IPR001841///Zinc finger, RING-type","[R144A_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RNF144A; EC=2.3.2.31 {ECO:0000250|UniProtKB:O60260}; AltName: Full=RING finger protein 144A; AltName: Full=UbcM4-interacting protein 4; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 4;+++[C9JLH4_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase RNF144A {ECO:0000313|Ensembl:ENSP00000414420}; Flags: Fragment;+++[H7C3G0_HUMAN|Unreviewed]RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|SAAS:SAAS01037474}; EC=2.3.2.31 {ECO:0000256|SAAS:SAAS01037474}; Flags: Fragment;"]
[9782,"'MATR3'",1858,2009,1933.5,"04140///Autophagy - animal+++04137///Mitophagy - animal","H00058///Amyotrophic lateral sclerosis (ALS)",null,null,"GO:0005637///nuclear inner membrane+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0016363///nuclear matrix","GO:0003676///nucleic acid binding+++GO:0005198///structural molecule activity+++GO:0003723///RNA binding+++GO:0042802///identical protein binding+++GO:0035198///miRNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0002218///activation of innate immune response+++GO:0010608///posttranscriptional regulation of gene expression+++GO:0045087///innate immune response+++GO:0002376///immune system process","IPR035979///RNA-binding domain superfamily+++IPR003604///Matrin/U1-C-like, C2H2-type zinc finger+++IPR034928///Matrin-3, RNA recognition motif 1+++IPR000504///RNA recognition motif domain+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR034930///Matrin-3, RNA recognition motif 2+++IPR000690///Matrin/U1-C, C2H2-type zinc finger","[MATR3_HUMAN|Reviewed]RecName: Full=Matrin-3;+++[A0A0R4J2E8_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000354346};+++[A0A1B0GX04_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421145}; Flags: Fragment;+++[A8MXP9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000378279};+++[B3KM87_HUMAN|Unreviewed]SubName: Full=cDNA FLJ10526 fis, clone NT2RP2000931, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG50899.1};+++[B4DF66_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55637, highly similar to Matrin-3 {ECO:0000313|EMBL:BAG57327.1};+++[D6R8Z5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422233}; Flags: Fragment;+++[D6R991_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423290}; Flags: Fragment;+++[D6R9F3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422137}; Flags: Fragment;+++[D6R9N0_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000423521}; Flags: Fragment;+++[D6RAM9_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000421666}; Flags: Fragment;+++[D6RAY2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424646}; Flags: Fragment;+++[D6RB45_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000424431}; Flags: Fragment;+++[D6RBI2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422700}; Flags: Fragment;+++[D6RBK5_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422649}; Flags: Fragment;+++[D6RBS2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422590}; Flags: Fragment;+++[D6RCM3_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427168};+++[D6RE02_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000425150}; Flags: Fragment;+++[D6REK4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426801}; Flags: Fragment;+++[D6REM6_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000426743};+++[D6RIA2_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000427557}; Flags: Fragment;+++[H0Y8T4_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000422054}; Flags: Fragment;+++[Q68E03_HUMAN|Unreviewed]SubName: Full=Matrin-3 {ECO:0000313|Ensembl:ENSP00000480093};+++[Q9H4N1_HUMAN|Unreviewed]SubName: Full=Clone CDABP0107 mRNA sequence {ECO:0000313|EMBL:AAG02007.1};"]
[9783,"'RIMS3'",65,96,80.5,{"$nulls":4},"GO:0030054///cell junction+++GO:0016020///membrane+++GO:0042734///presynaptic membrane+++GO:0098831///presynaptic active zone cytoplasmic component+++GO:0045202///synapse+++GO:0048788///cytoskeleton of presynaptic active zone+++GO:0048786///presynaptic active zone","GO:0017137///Rab GTPase binding+++GO:0044325///ion channel binding","GO:0048791///calcium ion-regulated exocytosis of neurotransmitter+++GO:0017156///calcium ion regulated exocytosis+++GO:0042391///regulation of membrane potential+++GO:0050806///positive regulation of synaptic transmission+++GO:0048167///regulation of synaptic plasticity+++GO:0006887///exocytosis+++GO:0006836///neurotransmitter transport+++GO:2000300///regulation of synaptic vesicle exocytosis","IPR035892///C2 domain superfamily+++IPR039032///Rim-like+++IPR000008///C2 domain","[RIMS3_HUMAN|Reviewed]RecName: Full=Regulating synaptic membrane exocytosis protein 3; Short=Nim3; AltName: Full=RIM3 gamma; AltName: Full=Rab-3-interacting molecule 3; Short=RIM 3;+++[L8EAQ2_HUMAN|Unreviewed]SubName: Full=Alternative protein RIMS3 {ECO:0000313|EMBL:CCQ43458.1};+++[X5D2V8_HUMAN|Unreviewed]SubName: Full=Regulating synaptic membrane exocytosis 3 isoform C {ECO:0000313|EMBL:AHW56609.1}; Flags: Fragment;"]
[9784,"'SNX17'",1414,1343,1378.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005737///cytoplasm+++GO:0032991///protein-containing complex+++GO:0005769///early endosome+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005768///endosome+++GO:0005623///cell+++GO:0010008///endosome membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005794///Golgi apparatus","GO:0050750///low-density lipoprotein particle receptor binding+++GO:0008289///lipid binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0005102///signaling receptor binding+++GO:0035091///phosphatidylinositol binding","GO:0006898///receptor-mediated endocytosis+++GO:0016197///endosomal transport+++GO:0003279///cardiac septum development+++GO:0006707///cholesterol catabolic process+++GO:0035904///aorta development+++GO:1990126///retrograde transport, endosome to plasma membrane+++GO:0015031///protein transport+++GO:0007165///signal transduction+++GO:0030100///regulation of endocytosis+++GO:0060976///coronary vasculature development+++GO:0006886///intracellular protein transport","IPR037836///SNX17, atypical FERM-like domain+++IPR036871///PX domain superfamily+++IPR011993///PH-like domain superfamily+++IPR037831///SNX17/27/31+++IPR028666///Sorting nexin-17+++IPR001683///Phox homologous domain+++IPR000159///Ras-associating (RA) domain","[SNX17_HUMAN|Reviewed]RecName: Full=Sorting nexin-17;+++[B4DDM3_HUMAN|Unreviewed]SubName: Full=Sorting nexin 17, isoform CRA_a {ECO:0000313|EMBL:EAX00584.1}; SubName: Full=cDNA FLJ51047, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60979.1}; SubName: Full=cDNA FLJ53821, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG56784.1}; SubName: Full=cDNA FLJ61770, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG58262.1};+++[B4DQ37_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56223, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG60799.1};+++[B4DTB8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ51699, highly similar to Sorting nexin-17 {ECO:0000313|EMBL:BAG61930.1};+++[F8WAZ0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000405399};+++[F8WEG6_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000401922};+++[F8WFA0_HUMAN|Unreviewed]SubName: Full=Sorting nexin-17 {ECO:0000313|Ensembl:ENSP00000399727};"]
[9785,"'DHX38'",646,598,622,"03040///Spliceosome",{"$nulls":3},"GO:0005634///nucleus+++GO:0071013///catalytic step 2 spliceosome+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005681///spliceosomal complex","GO:0000166///nucleotide binding+++GO:0004386///helicase activity+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0034459///ATP-dependent 3'-5' RNA helicase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding","GO:0000398///mRNA splicing, via spliceosome+++GO:0031124///mRNA 3'-end processing+++GO:0006397///mRNA processing+++GO:0006406///mRNA export from nucleus+++GO:0008380///RNA splicing+++GO:0006405///RNA export from nucleus","IPR007502///Helicase-associated domain+++IPR002464///DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR011709///Domain of unknown function DUF1605+++IPR011545///DEAD/DEAH box helicase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR001650///Helicase, C-terminal","[PRP16_HUMAN|Reviewed]RecName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; EC=3.6.4.13; AltName: Full=ATP-dependent RNA helicase DHX38; AltName: Full=DEAH box protein 38;+++[B4DM30_HUMAN|Unreviewed]SubName: Full=DEAH (Asp-Glu-Ala-His) box polypeptide 38, isoform CRA_d {ECO:0000313|EMBL:EAW59183.1}; SubName: Full=cDNA FLJ50987, highly similar to Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|EMBL:BAG59742.1};+++[H3BMS7_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000454521}; Flags: Fragment;+++[H3BQT9_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000455939}; Flags: Fragment;+++[H3BV01_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000457887}; Flags: Fragment;+++[J3KRT1_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462149};+++[J3KSA8_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462397}; Flags: Fragment;+++[J3KTG2_HUMAN|Unreviewed]SubName: Full=Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 {ECO:0000313|Ensembl:ENSP00000462965}; Flags: Fragment;"]
[9786,"'KIAA0586'",143,193,168,"05412///Arrhythmogenic right ventricular cardiomyopathy (ARVC)+++04140///Autophagy - animal+++04137///Mitophagy - animal","H00293///Arrhythmogenic right ventricular cardiomyopathy (ARVC)",null,null,"GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0036064///ciliary basal body+++GO:0001917///photoreceptor inner segment+++GO:0042995///cell projection+++GO:0005813///centrosome+++GO:0005737///cytoplasm","GO:0019904///protein domain specific binding+++GO:0043021///ribonucleoprotein complex binding+++GO:1990247///N6-methyladenosine-containing RNA binding+++GO:0004857///enzyme inhibitor activity+++GO:1990827///deaminase binding+++GO:0003729///mRNA binding","GO:0070201///regulation of establishment of protein localization+++GO:0007224///smoothened signaling pathway+++GO:0030030///cell projection organization+++GO:0060271///cilium assembly","IPR029246///Protein TALPID3","[TALD3_HUMAN|Reviewed]RecName: Full=Protein TALPID3;+++[A0A087WYM5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000481936};+++[B4DYW5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61484 {ECO:0000313|EMBL:BAG63877.1};+++[B7Z7W7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52366 {ECO:0000313|EMBL:BAH13753.1};+++[G3V2T5_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000450855}; Flags: Fragment;+++[G3V4J0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451831}; Flags: Fragment;+++[G3V5U9_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000452536};+++[H0YJF0_HUMAN|Unreviewed]SubName: Full=Protein TALPID3 {ECO:0000313|Ensembl:ENSP00000451356}; Flags: Fragment;+++[L0R885_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0586 {ECO:0000313|EMBL:CCO13756.1};"]
[9787,"'DLGAP5'",0,3,1.5,{"$nulls":4},"GO:0005819///spindle+++GO:0031616///spindle pole centrosome+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005634///nucleus+++GO:0005739///mitochondrion","GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding","GO:0007049///cell cycle+++GO:0007079///mitotic chromosome movement towards spindle pole+++GO:0023052///signaling+++GO:0006470///protein dephosphorylation+++GO:0045842///positive regulation of mitotic metaphase/anaphase transition+++GO:0008283///cell proliferation+++GO:0007221///positive regulation of transcription of Notch receptor target","IPR005026///SAPAP family","[DLGP5_HUMAN|Reviewed]RecName: Full=Disks large-associated protein 5; Short=DAP-5; AltName: Full=Discs large homolog 7; AltName: Full=Disks large-associated protein DLG7; AltName: Full=Hepatoma up-regulated protein; Short=HURP;+++[G3V4E5_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000451747}; Flags: Fragment;+++[G3V543_HUMAN|Unreviewed]SubName: Full=Disks large-associated protein 5 {ECO:0000313|Ensembl:ENSP00000452168};"]
[9788,"'MTSS1'",35,39.24,37.12,"00190///Oxidative phosphorylation+++04932///Non-alcoholic fatty liver disease (NAFLD)+++05012///Parkinson's disease+++01100///Metabolic pathways+++05016///Huntington's disease+++05010///Alzheimer's disease+++04714///Thermogenesis+++04140///Autophagy - animal+++04137///Mitophagy - animal+++04723///Retrograde endocannabinoid signaling","H00473///Mitochondrial complex I deficiency","M00147///NADH dehydrogenase (ubiquinone) 1 beta subcomplex",null,"GO:0005856///cytoskeleton+++GO:0015629///actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0001726///ruffle+++GO:0030139///endocytic vesicle","GO:0005102///signaling receptor binding+++GO:0042802///identical protein binding+++GO:0003779///actin binding+++GO:0003785///actin monomer binding+++GO:0005515///protein binding","GO:0072160///nephron tubule epithelial cell differentiation+++GO:0072102///glomerulus morphogenesis+++GO:0030036///actin cytoskeleton organization+++GO:0050680///negative regulation of epithelial cell proliferation+++GO:0007009///plasma membrane organization+++GO:0071498///cellular response to fluid shear stress+++GO:0030035///microspike assembly+++GO:0007155///cell adhesion+++GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:2001013///epithelial cell proliferation involved in renal tubule morphogenesis+++GO:0061333///renal tubule morphogenesis","IPR027267///AH/BAR domain superfamily+++IPR030127///I-BAR domain containing protein MIM/ABBA+++IPR013606///IMD/I-BAR domain+++IPR003124///WH2 domain+++IPR027682///I-BAR domain containing protein MIM","[MTSS1_HUMAN|Reviewed]RecName: Full=Metastasis suppressor protein 1; AltName: Full=Metastasis suppressor YGL-1; AltName: Full=Missing in metastasis protein;+++[A5YM41_HUMAN|Unreviewed]SubName: Full=MTSS1 protein {ECO:0000313|EMBL:ABQ59025.1};+++[E5RJX3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428145}; Flags: Fragment;+++[E7EWW5_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428319};+++[H0YAZ8_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428348}; Flags: Fragment;+++[H0YB53_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000428685}; Flags: Fragment;+++[H0YBL3_HUMAN|Unreviewed]SubName: Full=Metastasis suppressor protein 1 {ECO:0000313|Ensembl:ENSP00000429752}; Flags: Fragment;"]
[9789,"'SPCS2'",457,411,434,"03060///Protein export",null,null,"R04018///Acylneuraminyl hydrolase Galactosylceramide + N-Acetylneuraminate <=> GM4 + H2O","GO:0005787///signal peptidase complex+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0016020///membrane+++GO:0031090///organelle membrane+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005783///endoplasmic reticulum","GO:0016787///hydrolase activity+++GO:0008233///peptidase activity","GO:0006465///signal peptide processing+++GO:0006508///proteolysis+++GO:0045047///protein targeting to ER","IPR009582///Signal peptidase complex subunit 2","[SPCS2_HUMAN|Reviewed]RecName: Full=Signal peptidase complex subunit 2; EC=3.4.-.-; AltName: Full=Microsomal signal peptidase 25 kDa subunit; Short=SPase 25 kDa subunit;+++[A0A087WUC6_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000478550};+++[E9PI68_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000436759};+++[E9PL01_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000433439};+++[E9PRB9_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434248};+++[H0YE04_HUMAN|Unreviewed]SubName: Full=Signal peptidase complex subunit 2 {ECO:0000313|Ensembl:ENSP00000434706}; Flags: Fragment;"]
[9790,"'BMS1'",776.43,799.44,787.935,"03008///Ribosome biogenesis in eukaryotes","H01896///Aplasia cutis congenita",null,null,"GO:0005654///nucleoplasm+++GO:0030686///90S preribosome+++GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0003924///GTPase activity+++GO:0005525///GTP binding+++GO:0005524///ATP binding+++GO:0003723///RNA binding+++GO:0034511///U3 snoRNA binding+++GO:0000166///nucleotide binding","GO:0042254///ribosome biogenesis+++GO:0000462///maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0006364///rRNA processing","IPR012948///AARP2CN+++IPR007034///Ribosome biogenesis protein BMS1/TSR1, C-terminal+++IPR039761///Ribosome biogenesis protein Bms1/Tsr1+++IPR037875///Ribosome biogenesis protein Bms1, N-terminal+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR030387///Bms1/Tsr1-type G domain","[BMS1_HUMAN|Reviewed]RecName: Full=Ribosome biogenesis protein BMS1 homolog; AltName: Full=Ribosome assembly protein BMS1 homolog;"]
[9791,"'PTDSS1'",803,653,728,"00564///Glycerophospholipid metabolism+++01100///Metabolic pathways","H01832///Lenz-Majewski syndrome",null,"R07377///Phosphatidylcholine + L-Serine <=> Phosphatidylserine + Choline","GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005789///endoplasmic reticulum membrane","GO:0016740///transferase activity","GO:0008654///phospholipid biosynthetic process+++GO:0006629///lipid metabolic process+++GO:0006659///phosphatidylserine biosynthetic process","IPR004277///Phosphatidyl serine synthase","[PTSS1_HUMAN|Reviewed]RecName: Full=Phosphatidylserine synthase 1; Short=PSS-1; Short=PtdSer synthase 1; EC=2.7.8.29; AltName: Full=Serine-exchange enzyme I;+++[J3KNR6_HUMAN|Unreviewed]SubName: Full=Phosphatidylserine synthase 1, isoform CRA_a {ECO:0000313|EMBL:EAW91753.1};+++[Q9BSY0_HUMAN|Unreviewed]SubName: Full=PTDSS1 protein {ECO:0000313|EMBL:AAH04502.2}; Flags: Fragment;"]
[9792,"'SERTAD2'",470,735,602.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0003713///transcription coactivator activity","GO:0030308///negative regulation of cell growth+++GO:0045893///positive regulation of transcription, DNA-templated","IPR009263///SERTA domain","[SRTD2_HUMAN|Reviewed]RecName: Full=SERTA domain-containing protein 2; AltName: Full=Transcriptional regulator interacting with the PHD-bromodomain 2; Short=TRIP-Br2;"]
[9793,"'CKAP5'",1175,1274,1224.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0000776///kinetochore+++GO:0016020///membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0000930///gamma-tubulin complex+++GO:0000775///chromosome, centromeric region+++GO:0000777///condensed chromosome kinetochore+++GO:0005813///centrosome+++GO:0000922///spindle pole+++GO:0005886///plasma membrane+++GO:0005694///chromosome+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0005819///spindle+++GO:0032991///protein-containing complex+++GO:0005730///nucleolus+++GO:0005815///microtubule organizing center+++GO:0035371///microtubule plus-end","GO:0051010///microtubule plus-end binding+++GO:0045296///cadherin binding+++GO:0005515///protein binding","GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0007098///centrosome cycle+++GO:0007019///microtubule depolymerization+++GO:0051301///cell division+++GO:0051298///centrosome duplication+++GO:0050658///RNA transport+++GO:0007051///spindle organization+++GO:0030951///establishment or maintenance of microtubule cytoskeleton polarity+++GO:0046785///microtubule polymerization+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0007049///cell cycle","IPR024395///CLASP N-terminal domain+++IPR034085///TOG domain+++IPR011989///Armadillo-like helical+++IPR021133///HEAT, type 2+++IPR016024///Armadillo-type fold","[CKAP5_HUMAN|Reviewed]RecName: Full=Cytoskeleton-associated protein 5; AltName: Full=Colonic and hepatic tumor overexpressed gene protein; Short=Ch-TOG;+++[E9PQH5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436769}; Flags: Fragment;+++[H0YCF6_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000431509}; Flags: Fragment;+++[H0YDX5_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000434523}; Flags: Fragment;+++[H0YEK7_HUMAN|Unreviewed]SubName: Full=Cytoskeleton-associated protein 5 {ECO:0000313|Ensembl:ENSP00000436052}; Flags: Fragment;+++[Q8IYN5_HUMAN|Unreviewed]SubName: Full=CKAP5 protein {ECO:0000313|EMBL:AAH35554.1};"]
[9794,"'MAML1'",606,835,720.5,"04330///Notch signaling pathway+++04658///Th1 and Th2 cell differentiation+++05165///Human papillomavirus infection","H01508///Salivary gland cancer",null,null,"GO:0002193///MAML1-RBP-Jkappa- ICN1 complex+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0003713///transcription coactivator activity+++GO:0005515///protein binding+++GO:0042605///peptide antigen binding+++GO:0019901///protein kinase binding","GO:0045445///myoblast differentiation+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0006468///protein phosphorylation+++GO:0007221///positive regulation of transcription of Notch receptor target+++GO:0010831///positive regulation of myotube differentiation+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007219///Notch signaling pathway+++GO:0003162///atrioventricular node development+++GO:0045747///positive regulation of Notch signaling pathway+++GO:0060928///atrioventricular node cell development","IPR019082///Neurogenic mastermind-like, N-terminal","[MAML1_HUMAN|Reviewed]RecName: Full=Mastermind-like protein 1; Short=Mam-1;"]
[9796,"'PHYHIP'",131,175,153,"04623///Cytosolic DNA-sensing pathway+++01100///Metabolic pathways+++04137///Mitophagy - animal+++05169///Epstein-Barr virus infection+++00230///Purine metabolism+++00240///Pyrimidine metabolism+++04140///Autophagy - animal+++03020///RNA polymerase",null,"M00181///RNA polymerase III, eukaryotes","R00441///GTP:RNA guanylyltransferase (DNA-directed); GTP:RNA GTP + RNA <=> Diphosphate + RNA+++R00435///ATP:polynucleotide adenylyltransferase; ATP:RNA ATP + RNA <=> Diphosphate + RNA+++R00443///UTP:RNA uridylyltransferase UTP + RNA <=> Diphosphate + RNA+++R00442///CTP:RNA cytidylyltransferase (DNA-directed); CTP:RNA CTP + RNA <=> Diphosphate + RNA","GO:0000790///nuclear chromatin+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005666///RNA polymerase III complex+++GO:0016607///nuclear speck","GO:0003682///chromatin binding+++GO:0003677///DNA binding+++GO:0003899///DNA-directed 5'-3' RNA polymerase activity","GO:0006383///transcription by RNA polymerase III+++GO:0032728///positive regulation of interferon-beta production+++GO:0045087///innate immune response+++GO:0051607///defense response to virus+++GO:0045089///positive regulation of innate immune response","IPR013783///Immunoglobulin-like fold+++IPR036116///Fibronectin type III superfamily+++IPR003961///Fibronectin type III","[PHYIP_HUMAN|Reviewed]RecName: Full=Phytanoyl-CoA hydroxylase-interacting protein; AltName: Full=Phytanoyl-CoA hydroxylase-associated protein 1; Short=PAHX-AP1; Short=PAHXAP1;+++[E5RHN5_HUMAN|Unreviewed]SubName: Full=Phytanoyl-CoA hydroxylase-interacting protein {ECO:0000313|Ensembl:ENSP00000430870}; Flags: Fragment;"]
[9797,"'TATDN2'",444,474,459,{"$nulls":4},"GO:0016607///nuclear speck+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0004518///nuclease activity+++GO:0016788///hydrolase activity, acting on ester bonds+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity+++GO:0016888///endodeoxyribonuclease activity, producing 5'-phosphomonoesters","GO:0006259///DNA metabolic process+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0036498///IRE1-mediated unfolded protein response","IPR032466///Metal-dependent hydrolase+++IPR018228///Deoxyribonuclease, TatD-related, conserved site+++IPR001130///TatD family","[TATD2_HUMAN|Reviewed]RecName: Full=Putative deoxyribonuclease TATDN2; EC=3.1.21.-;+++[A0A024R2F3_HUMAN|Unreviewed]SubName: Full=TatD DNase domain containing 2, isoform CRA_a {ECO:0000313|EMBL:EAW64071.1};+++[H7BZJ2_HUMAN|Unreviewed]SubName: Full=Putative deoxyribonuclease TATDN2 {ECO:0000313|Ensembl:ENSP00000389896}; Flags: Fragment;"]
[9798,"'IST1'",991,934,962.5,"04144///Endocytosis",{"$nulls":3},"GO:0043231///intracellular membrane-bounded organelle+++GO:0000785///chromatin+++GO:0070062///extracellular exosome+++GO:0005813///centrosome+++GO:0005576///extracellular region+++GO:0031410///cytoplasmic vesicle+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0005737///cytoplasm+++GO:0005635///nuclear envelope+++GO:0005856///cytoskeleton+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0035578///azurophil granule lumen","GO:0044877///protein-containing complex binding+++GO:0045296///cadherin binding+++GO:0090541///MIT domain binding+++GO:0019904///protein domain specific binding+++GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0061640///cytoskeleton-dependent cytokinesis+++GO:0043312///neutrophil degranulation+++GO:0036258///multivesicular body assembly+++GO:1904903///ESCRT III complex disassembly+++GO:0048672///positive regulation of collateral sprouting+++GO:0051301///cell division+++GO:0019076///viral release from host cell+++GO:0045184///establishment of protein localization+++GO:0009838///abscission+++GO:0008104///protein localization+++GO:0046745///viral capsid secondary envelopment+++GO:0045862///positive regulation of proteolysis+++GO:0015031///protein transport+++GO:0007049///cell cycle","IPR005061///Vacuolar protein sorting-associated protein Ist1","[IST1_HUMAN|Reviewed]RecName: Full=IST1 homolog; Short=hIST1; AltName: Full=Putative MAPK-activating protein PM28;+++[B4DXC9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59095 {ECO:0000313|EMBL:BAG63341.1};+++[E9PF00_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000410081};+++[F5GXM3_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000398505}; Flags: Fragment;+++[H3BMU1_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000454541}; Flags: Fragment;+++[H3BPP6_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455409}; Flags: Fragment;+++[H3BQ38_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455590}; Flags: Fragment;+++[H3BQF7_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000455757}; Flags: Fragment;+++[H3BRE2_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000456200}; Flags: Fragment;+++[H3BUI0_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000457646}; Flags: Fragment;+++[J3KR23_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000414942}; Flags: Fragment;+++[J3QQP8_HUMAN|Unreviewed]SubName: Full=IST1 homolog {ECO:0000313|Ensembl:ENSP00000463833};"]
[98,"'ACYP2'",213,174,193.5,"00627///Aminobenzoate degradation+++01120///Microbial metabolism in diverse environments+++00620///Pyruvate metabolism",null,null,"R00317///Acetyl phosphate phosphohydrolase   Acetyl phosphate + H2O <=> Acetate + Orthophosphate+++R01515///3-Phospho-D-glyceroyl phosphate phosphohydrolase   3-Phospho-D-glyceroyl phosphate + H2O <=> 3-Phospho-D-glycerate + Orthophosphate+++R01421///Benzoyl phosphate phosphohydrolase   Benzoyl phosphate + H2O <=> Benzoate + Orthophosphate","GO:0005623///cell+++GO:1990111///spermatoproteasome complex+++GO:0017053///transcriptional repressor complex+++GO:0035868///alphav-beta3 integrin-HMGB1 complex+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005839///proteasome core complex+++GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0005793///endoplasmic reticulum-Golgi intermediate compartment+++GO:0000793///condensed chromosome+++GO:0070062///extracellular exosome","GO:0042802///identical protein binding+++GO:0003998///acylphosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0006796///phosphate-containing compound metabolic process","IPR036046///Acylphosphatase-like domain superfamily+++IPR001792///Acylphosphatase-like domain+++IPR017968///Acylphosphatase, conserved site+++IPR020456///Acylphosphatase","[ACYP2_HUMAN|Reviewed]RecName: Full=Acylphosphatase-2; EC=3.6.1.7; AltName: Full=Acylphosphatase, muscle type isozyme; AltName: Full=Acylphosphate phosphohydrolase 2;+++[A0A140VJD7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[D6W5B6_HUMAN|Unreviewed]SubName: Full=Acylphosphatase 2, muscle type, isoform CRA_a {ECO:0000313|EMBL:EAX00155.1};+++[E9PF46_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[F8WA34_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553};+++[Q4ZFV7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ACYP2 {ECO:0000313|EMBL:AAX88874.1}; Flags: Fragment;+++[Q53TK7_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX1_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520, ECO:0000256|RuleBase:RU000553}; Flags: Fragment;+++[U3KPX8_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475333};+++[U3KQ09_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475424};+++[U3KQ94_HUMAN|Unreviewed]SubName: Full=Acylphosphatase-2 {ECO:0000313|Ensembl:ENSP00000475658}; SubName: Full=HCG2040114, isoform CRA_a {ECO:0000313|EMBL:EAX00159.1};+++[U3KQL2_HUMAN|Unreviewed]RecName: Full=Acylphosphatase {ECO:0000256|PROSITE-ProRule:PRU00520}; EC=3.6.1.7 {ECO:0000256|PROSITE-ProRule:PRU00520};"]
[9801,"'MRPL19'",264,338,301,"03010///Ribosome",null,"M00178///Ribosome, bacteria",null,"GO:0005743///mitochondrial inner membrane+++GO:0015934///large ribosomal subunit+++GO:0005840///ribosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0005762///mitochondrial large ribosomal subunit+++GO:0031965///nuclear membrane","GO:0003735///structural constituent of ribosome+++GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0006412///translation+++GO:0070126///mitochondrial translational termination+++GO:0070125///mitochondrial translational elongation+++GO:1990830///cellular response to leukemia inhibitory factor","IPR008991///Translation protein SH3-like domain superfamily+++IPR001857///Ribosomal protein L19+++IPR038657///Ribosomal protein L19 superfamily","[RM19_HUMAN|Reviewed]RecName: Full=39S ribosomal protein L19, mitochondrial; Short=L19mt; Short=MRP-L19; AltName: Full=39S ribosomal protein L15, mitochondrial; Short=L15mt; Short=MRP-L15; AltName: Full=Mitochondrial large ribosomal subunit protein bL19m {ECO:0000303|PubMed:25278503}; Flags: Precursor;+++[A0A0A0MRF4_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000351639};+++[H7C2J0_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000406267}; Flags: Fragment;+++[S4R3W9_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000474821}; Flags: Fragment;+++[S4R455_HUMAN|Unreviewed]SubName: Full=39S ribosomal protein L19, mitochondrial {ECO:0000313|Ensembl:ENSP00000475090}; Flags: Fragment;"]
[9802,"'DAZAP2'",2115,2280,2197.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0032991///protein-containing complex+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0030971///receptor tyrosine kinase binding+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0043539///protein serine/threonine kinase activator activity+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding","GO:0071902///positive regulation of protein serine/threonine kinase activity","IPR022730///DAZ associated protein 2","[DAZP2_HUMAN|Reviewed]RecName: Full=DAZ-associated protein 2; AltName: Full=Deleted in azoospermia-associated protein 2;+++[A0A024R110_HUMAN|Unreviewed]SubName: Full=DAZ associated protein 2, isoform CRA_a {ECO:0000313|EMBL:EAW58182.1};+++[E9PE89_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000404968};+++[F8VUW5_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000447842};+++[S4R3Q0_HUMAN|Unreviewed]SubName: Full=DAZ-associated protein 2 {ECO:0000313|Ensembl:ENSP00000474597};"]
[9804,"'TOMM20'",1409,1640,1524.5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005740///mitochondrial envelope+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0044233///Mitochondria-associated ER Membrane+++GO:0005742///mitochondrial outer membrane translocase complex+++GO:0031307///integral component of mitochondrial outer membrane+++GO:0005741///mitochondrial outer membrane","GO:0015450///P-P-bond-hydrolysis-driven protein transmembrane transporter activity+++GO:0030943///mitochondrion targeting sequence binding+++GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding+++GO:0051082///unfolded protein binding","GO:0016031///tRNA import into mitochondrion+++GO:0030150///protein import into mitochondrial matrix+++GO:0006626///protein targeting to mitochondrion+++GO:0006886///intracellular protein transport+++GO:0014850///response to muscle activity+++GO:0016579///protein deubiquitination+++GO:1905242///response to 3,3',5-triiodo-L-thyronine+++GO:0006605///protein targeting+++GO:0015031///protein transport+++GO:0070096///mitochondrial outer membrane translocase complex assembly","IPR022422///Protein import receptor MAS20, metazoan+++IPR002056///Protein import receptor MAS20+++IPR023392///Mitochondrial outer membrane translocase complex, Tom20 domain superfamily","[TOM20_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM20 homolog; AltName: Full=Mitochondrial 20 kDa outer membrane protein; AltName: Full=Outer mitochondrial membrane receptor Tom20;+++[A0A024R3W2_HUMAN|Unreviewed]SubName: Full=Translocase of outer mitochondrial membrane 20 homolog (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW70004.1};"]
[9805,"'SCRN1'",1908,2118,2013,{"$nulls":4},"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016805///dipeptidase activity+++GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0006887///exocytosis+++GO:0006508///proteolysis","IPR005322///Peptidase C69, dipeptidase A","[SCRN1_HUMAN|Reviewed]RecName: Full=Secernin-1;+++[A0A024RA21_HUMAN|Unreviewed]SubName: Full=Secernin 1, isoform CRA_a {ECO:0000313|EMBL:EAW93927.1};+++[A0A090N7T9_HUMAN|Unreviewed]SubName: Full=Secernin 1 {ECO:0000313|EMBL:EAL24458.1};+++[B8ZZP4_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000387052};+++[C9J7U9_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000406289}; Flags: Fragment;+++[C9K052_HUMAN|Unreviewed]SubName: Full=Secernin-1 {ECO:0000313|Ensembl:ENSP00000413184}; Flags: Fragment;"]
[9806,"'SPOCK2'",20,54,37,{"$nulls":4},"GO:0005576///extracellular region+++GO:0005615///extracellular space+++GO:0031012///extracellular matrix","GO:0005509///calcium ion binding+++GO:0008191///metalloendopeptidase inhibitor activity+++GO:0050840///extracellular matrix binding+++GO:0005539///glycosaminoglycan binding+++GO:0005518///collagen binding","GO:0010811///positive regulation of cell-substrate adhesion+++GO:0019800///peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan+++GO:0010951///negative regulation of endopeptidase activity+++GO:2000147///positive regulation of cell motility+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:0007416///synapse assembly+++GO:0045595///regulation of cell differentiation+++GO:0030198///extracellular matrix organization","IPR036857///Thyroglobulin type-1 superfamily+++IPR036058///Kazal domain superfamily+++IPR019577///SPARC/Testican, calcium-binding domain+++IPR000716///Thyroglobulin type-1+++IPR011992///EF-hand domain pair+++IPR002350///Kazal domain","[TICN2_HUMAN|Reviewed]RecName: Full=Testican-2; AltName: Full=SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2; Flags: Precursor;+++[A0A024QZQ5_HUMAN|Unreviewed]SubName: Full=Sparc/osteonectin, cwcv and kazal-like domains proteoglycan (Testican) 2, isoform CRA_b {ECO:0000313|EMBL:EAW54443.1};+++[F5H283_HUMAN|Unreviewed]SubName: Full=Testican-2 {ECO:0000313|Ensembl:ENSP00000439445};+++[L8E8K3_HUMAN|Unreviewed]SubName: Full=Alternative protein SPOCK2 {ECO:0000313|EMBL:CCQ43459.1};"]
[9807,"'IP6K1'",768,906,837,"04138///Autophagy - yeast+++04070///Phosphatidylinositol signaling system",null,null,"R10548///ATP:1D-myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 5-phosphotransferase   ATP + 1-Diphosinositol pentakisphosphate <=> ADP + 1D-myo-Inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate+++R09087///ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase   ATP + Phytic acid <=> ADP + 5-PP-InsP5","GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0001650///fibrillar center+++GO:0005634///nucleus+++GO:0005829///cytosol","GO:0052839///inositol diphosphate tetrakisphosphate kinase activity+++GO:0052723///inositol hexakisphosphate 1-kinase activity+++GO:0000829///inositol heptakisphosphate kinase activity+++GO:0016301///kinase activity+++GO:0000832///inositol hexakisphosphate 5-kinase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0000827///inositol-1,3,4,5,6-pentakisphosphate kinase activity+++GO:0000828///inositol hexakisphosphate kinase activity+++GO:0052724///inositol hexakisphosphate 3-kinase activity+++GO:0005524///ATP binding+++GO:0052836///inositol 5-diphosphate pentakisphosphate 5-kinase activity","GO:0043647///inositol phosphate metabolic process+++GO:0120163///negative regulation of cold-induced thermogenesis+++GO:0046854///phosphatidylinositol phosphorylation+++GO:0032958///inositol phosphate biosynthetic process+++GO:0016310///phosphorylation","IPR005522///Inositol polyphosphate kinase+++IPR038286///Inositol polyphosphate kinase superfamily","[IP6K1_HUMAN|Reviewed]RecName: Full=Inositol hexakisphosphate kinase 1; Short=InsP6 kinase 1; EC=2.7.4.21; AltName: Full=Inositol hexaphosphate kinase 1;+++[A0A024R2X2_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[C9JNA8_HUMAN|Unreviewed]RecName: Full=Kinase {ECO:0000256|RuleBase:RU363090}; EC=2.7.-.- {ECO:0000256|RuleBase:RU363090};+++[L8EAR7_HUMAN|Unreviewed]SubName: Full=Alternative protein IP6K1 {ECO:0000313|EMBL:CCQ43876.1};"]
[9810,"'RNF40'",2590,2303,2446.5,{"$nulls":4},"GO:0033503///HULC complex+++GO:0032991///protein-containing complex+++GO:0005829///cytosol+++GO:0019898///extrinsic component of membrane+++GO:0005634///nucleus+++GO:0000151///ubiquitin ligase complex+++GO:0043679///axon terminus+++GO:0043005///neuron projection+++GO:0005654///nucleoplasm+++GO:0016020///membrane","GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0016740///transferase activity+++GO:0044877///protein-containing complex binding+++GO:0003730///mRNA 3'-UTR binding+++GO:0031624///ubiquitin conjugating enzyme binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0017075///syntaxin-1 binding+++GO:0042803///protein homodimerization activity","GO:0043434///response to peptide hormone+++GO:0016567///protein ubiquitination+++GO:1902916///positive regulation of protein polyubiquitination+++GO:0007346///regulation of mitotic cell cycle+++GO:0006325///chromatin organization+++GO:2001168///positive regulation of histone H2B ubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:1900364///negative regulation of mRNA polyadenylation+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0033523///histone H2B ubiquitination+++GO:0010390///histone monoubiquitination","IPR017907///Zinc finger, RING-type, conserved site+++IPR013956///E3 ubiquitin ligase Bre1+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type","[BRE1B_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase BRE1B; Short=BRE1-B; EC=2.3.2.27 {ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:19410543}; AltName: Full=95 kDa retinoblastoma-associated protein; Short=RBP95; AltName: Full=RING finger protein 40; AltName: Full=RING-type E3 ubiquitin transferase BRE1B {ECO:0000305};+++[A0A087WTK2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A0A0S2Z4Z2_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[A0A0S2Z537_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[A8K6K1_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BP71_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038};+++[H3BQ99_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BS50_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[H3BUL6_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[I3L332_HUMAN|Unreviewed]RecName: Full=E3 ubiquitin protein ligase {ECO:0000256|RuleBase:RU365038}; EC=2.3.2.27 {ECO:0000256|RuleBase:RU365038}; Flags: Fragment;+++[R4GN66_HUMAN|Unreviewed]SubName: Full=E3 ubiquitin-protein ligase BRE1B {ECO:0000313|Ensembl:ENSP00000473507}; Flags: Fragment;"]
[9811,"'CTIF'",1604,1772,1688,null,"H00480///Non-syndromic X-linked mental retardation+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H01852///Postaxial polydactyly",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0008494///translation activator activity+++GO:0003723///RNA binding+++GO:0005515///protein binding","GO:0045727///positive regulation of translation+++GO:0006446///regulation of translational initiation+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0006417///regulation of translation","IPR016024///Armadillo-type fold+++IPR016021///MIF4G-like domain superfamily+++IPR003890///MIF4G-like, type 3","[CTIF_HUMAN|Reviewed]RecName: Full=CBP80/20-dependent translation initiation factor;+++[A0A024R259_HUMAN|Unreviewed]SubName: Full=KIAA0427, isoform CRA_a {ECO:0000313|EMBL:EAW62927.1};+++[K7EK08_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000465405}; Flags: Fragment;+++[K7EPK6_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467425}; Flags: Fragment;+++[K7EQS5_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467957}; Flags: Fragment;+++[K7EQS9_HUMAN|Unreviewed]SubName: Full=CBP80/20-dependent translation initiation factor {ECO:0000313|Ensembl:ENSP00000467965}; Flags: Fragment;"]
[9812,"'DELE1'",802,856,829,"04137///Mitophagy - animal+++04140///Autophagy - animal","H00606///Early infantile epileptic encephalopathy+++H01775///PCDH19-related epilepsy syndrome",null,null,"GO:0005739///mitochondrion","GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0043281///regulation of cysteine-type endopeptidase activity involved in apoptotic process","IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR006597///Sel1-like repeat","[DELE1_HUMAN|Reviewed]RecName: Full=DAP3-binding cell death enhancer 1 {ECO:0000312|HGNC:HGNC:28969}; AltName: Full=Death ligand signal enhancer {ECO:0000303|PubMed:20563667}; Flags: Precursor;+++[D6RBI8_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000422686}; Flags: Fragment;+++[H0YA48_HUMAN|Unreviewed]SubName: Full=DAP3-binding cell death enhancer 1 {ECO:0000313|Ensembl:ENSP00000426138}; Flags: Fragment;"]
[9813,"'EFCAB14'",882,1232,1057,{"$nulls":4},"GO:0016021///integral component of membrane","GO:0046872///metal ion binding+++GO:0005509///calcium ion binding",null,"IPR002048///EF-hand domain+++IPR011992///EF-hand domain pair","[EFC14_HUMAN|Reviewed]RecName: Full=EF-hand calcium-binding domain-containing protein 14;+++[S4R3Q1_HUMAN|Unreviewed]SubName: Full=EF-hand calcium-binding domain-containing protein 14 {ECO:0000313|Ensembl:ENSP00000474599}; Flags: Fragment;"]
[9814,"'SFI1'",160,189.07,174.535,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005739///mitochondrion+++GO:0005856///cytoskeleton+++GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005814///centriole","GO:0016829///lyase activity+++GO:0016831///carboxy-lyase activity+++GO:0005515///protein binding+++GO:0004609///phosphatidylserine decarboxylase activity+++GO:0019902///phosphatase binding","GO:0006629///lipid metabolic process+++GO:0010923///negative regulation of phosphatase activity+++GO:0016540///protein autoprocessing+++GO:0097711///ciliary basal body-plasma membrane docking+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0008654///phospholipid biosynthetic process+++GO:0006646///phosphatidylethanolamine biosynthetic process+++GO:0000086///G2/M transition of mitotic cell cycle","IPR030516///Protein SFI1 homologue","[SFI1_HUMAN|Reviewed]RecName: Full=Protein SFI1 homolog; Short=hSFI1;+++[A0A024R1K2_HUMAN|Unreviewed]SubName: Full=Sfi1 homolog, spindle assembly associated (Yeast), isoform CRA_a {ECO:0000313|EMBL:EAW59983.1};+++[D3YTJ2_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000401199};+++[E5RJU6_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000430488};+++[H0Y5I7_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000398871}; Flags: Fragment;+++[H0Y836_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000416931}; Flags: Fragment;+++[H7BZF3_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000389364}; Flags: Fragment;+++[H7C2F1_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000405541}; Flags: Fragment;+++[X6RJF9_HUMAN|Unreviewed]SubName: Full=Protein SFI1 homolog {ECO:0000313|Ensembl:ENSP00000411793}; Flags: Fragment;"]
[9815,"'GIT2'",1214,1503,1358.5,"04144///Endocytosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0005654///nucleoplasm","GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0005096///GTPase activator activity","GO:0043547///positive regulation of GTPase activity+++GO:0008277///regulation of G protein-coupled receptor signaling pathway+++GO:0016310///phosphorylation","IPR032352///Arf GTPase-activating protein GIT1/2, coiled-coil domain+++IPR020683///Ankyrin repeat-containing domain+++IPR022018///ARF GTPase-activating protein GIT1, C-terminal+++IPR038508///ArfGAP domain superfamily+++IPR002110///Ankyrin repeat+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR013724///GIT, Spa2 homology (SHD) domain+++IPR037278///ARFGAP/RecO-like zinc finger+++IPR001164///Arf GTPase activating protein","[GIT2_HUMAN|Reviewed]RecName: Full=ARF GTPase-activating protein GIT2; Short=ARF GAP GIT2; AltName: Full=Cool-interacting tyrosine-phosphorylated protein 2; Short=CAT-2; Short=CAT2; AltName: Full=G protein-coupled receptor kinase-interactor 2; AltName: Full=GRK-interacting protein 2;+++[A0A024RBI8_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase interactor 2, isoform CRA_a {ECO:0000313|EMBL:EAW97886.1};+++[B5BU58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70108.1};+++[F8VXI9_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000448832};+++[F8W822_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000323833};+++[F8WAK2_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000346585};+++[Q68DM7_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G01261 {ECO:0000313|EMBL:CAH18193.1}; Flags: Fragment;+++[Q6FI58_HUMAN|Unreviewed]SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 {ECO:0000313|EMBL:BAG70242.1}; SubName: Full=G protein-coupled receptor kinase-interactor 2 isoform 4 variant {ECO:0000313|EMBL:BAD96456.1}; SubName: Full=GIT2 protein {ECO:0000313|EMBL:CAG38599.1};+++[R4GNG3_HUMAN|Unreviewed]SubName: Full=ARF GTPase-activating protein GIT2 {ECO:0000313|Ensembl:ENSP00000473637}; Flags: Fragment;"]
[9816,"'URB2'",116,133,124.5,{"$nulls":4},"GO:0030496///midbody+++GO:0005730///nucleolus+++GO:0005634///nucleus+++GO:0016235///aggresome",null,"GO:0042254///ribosome biogenesis","IPR018849///Nucleolar 27S pre-rRNA processing, Urb2/Npa2, C-terminal","[URB2_HUMAN|Reviewed]RecName: Full=Unhealthy ribosome biogenesis protein 2 homolog;+++[Q5VYD0_HUMAN|Unreviewed]SubName: Full=Unhealthy ribosome biogenesis protein 2 homolog {ECO:0000313|Ensembl:ENSP00000395107}; Flags: Fragment;+++[Q6PCC8_HUMAN|Unreviewed]SubName: Full=URB2 protein {ECO:0000313|EMBL:AAH59381.1}; Flags: Fragment;"]
[9817,"'KEAP1'",892,764,828,"05418///Fluid shear stress and atherosclerosis+++05200///Pathways in cancer+++04120///Ubiquitin mediated proteolysis+++05225///Hepatocellular carcinoma","H00048///Hepatocellular carcinoma",null,null,"GO:0005884///actin filament+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005783///endoplasmic reticulum+++GO:0005829///cytosol+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0030496///midbody+++GO:0005634///nucleus+++GO:0032991///protein-containing complex","GO:0042802///identical protein binding+++GO:0008134///transcription factor binding+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0097718///disordered domain specific binding","GO:0043433///negative regulation of DNA-binding transcription factor activity+++GO:0043687///post-translational protein modification+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0010499///proteasomal ubiquitin-independent protein catabolic process+++GO:0042994///cytoplasmic sequestering of transcription factor+++GO:0071353///cellular response to interleukin-4+++GO:0016032///viral process+++GO:0006355///regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0016567///protein ubiquitination+++GO:0045604///regulation of epidermal cell differentiation","IPR030563///Kelch-like ECH-associated protein 1+++IPR006652///Kelch repeat type 1+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR011705///BTB/Kelch-associated+++IPR017096///BTB-kelch protein+++IPR000210///BTB/POZ domain+++IPR015915///Kelch-type beta propeller","[KEAP1_HUMAN|Reviewed]RecName: Full=Kelch-like ECH-associated protein 1; AltName: Full=Cytosolic inhibitor of Nrf2; Short=INrf2; AltName: Full=Kelch-like protein 19;+++[A0A024R7C0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1, isoform CRA_a {ECO:0000313|EMBL:EAW84112.1};+++[K7EJ49_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465024}; Flags: Fragment;+++[K7EJD8_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000465126}; Flags: Fragment;+++[K7EMY1_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000466704}; Flags: Fragment;+++[K7EPZ3_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000467601}; Flags: Fragment;+++[K7EQX2_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468014}; Flags: Fragment;+++[K7ESE0_HUMAN|Unreviewed]SubName: Full=Kelch-like ECH-associated protein 1 {ECO:0000313|Ensembl:ENSP00000468671}; Flags: Fragment;"]
[9818,"'NUP58'",340,401,370.5,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0031965///nuclear membrane+++GO:0005634///nucleus+++GO:0005635///nuclear envelope+++GO:0016020///membrane+++GO:0005643///nuclear pore+++GO:0032991///protein-containing complex","GO:0005515///protein binding+++GO:0008139///nuclear localization sequence binding+++GO:0017056///structural constituent of nuclear pore","GO:0015031///protein transport+++GO:0006913///nucleocytoplasmic transport+++GO:0006406///mRNA export from nucleus+++GO:0016032///viral process+++GO:0051260///protein homooligomerization+++GO:0051028///mRNA transport+++GO:0042306///regulation of protein import into nucleus+++GO:0051290///protein heterotetramerization+++GO:0051291///protein heterooligomerization+++GO:0070208///protein heterotrimerization","IPR024882///Nucleoporin p58/p45","[NUP58_HUMAN|Reviewed]RecName: Full=Nucleoporin p58/p45 {ECO:0000305}; AltName: Full=58 kDa nucleoporin {ECO:0000312|HGNC:HGNC:20261}; AltName: Full=Nucleoporin-like protein 1;+++[F8WBZ1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418244};+++[F8WC35_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418904};+++[F8WCJ8_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000418341};+++[H7BYF2_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000371166}; Flags: Fragment;+++[Q5JRG1_HUMAN|Unreviewed]SubName: Full=Nucleoporin p58/p45 {ECO:0000313|Ensembl:ENSP00000408147}; Flags: Fragment;"]
[9819,"'TSC22D2'",680,886,783,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003700///DNA-binding transcription factor activity","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006970///response to osmotic stress","IPR000580///TSC-22 / Dip / Bun","[T22D2_HUMAN|Reviewed]RecName: Full=TSC22 domain family protein 2; AltName: Full=TSC22-related-inducible leucine zipper protein 4;+++[B4DN36_HUMAN|Unreviewed]SubName: Full=TSC22 domain family, member 2, isoform CRA_d {ECO:0000313|EMBL:EAW78841.1}; SubName: Full=cDNA FLJ51900, highly similar to TSC22 domain family protein 2 {ECO:0000313|EMBL:BAG60098.1};+++[H0Y865_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000417747}; Flags: Fragment;+++[H0Y8E9_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000420689}; Flags: Fragment;+++[H7C4U3_HUMAN|Unreviewed]SubName: Full=TSC22 domain family protein 2 {ECO:0000313|Ensembl:ENSP00000418149}; Flags: Fragment;"]
[9820,"'CUL7'",942,1021,981.5,"04120///Ubiquitin mediated proteolysis","H00509///3M syndrome",null,null,"GO:0005813///centrosome+++GO:0005829///cytosol+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0005856///cytoskeleton+++GO:0005815///microtubule organizing center+++GO:0005680///anaphase-promoting complex+++GO:1990393///3M complex+++GO:0005794///Golgi apparatus+++GO:0005737///cytoplasm+++GO:0048471///perinuclear region of cytoplasm","GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding","GO:0007030///Golgi organization+++GO:0006508///proteolysis+++GO:0001890///placenta development+++GO:0000226///microtubule cytoskeleton organization+++GO:0050775///positive regulation of dendrite morphogenesis+++GO:0036498///IRE1-mediated unfolded protein response+++GO:0001570///vasculogenesis+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0043687///post-translational protein modification+++GO:0007088///regulation of mitotic nuclear division+++GO:0001837///epithelial to mesenchymal transition+++GO:0000281///mitotic cytokinesis+++GO:0016567///protein ubiquitination+++GO:0016032///viral process","IPR036317///Cullin homology domain superfamily+++IPR021097///CPH domain+++IPR016024///Armadillo-type fold+++IPR008979///Galactose-binding-like domain superfamily+++IPR019559///Cullin protein, neddylation domain+++IPR004939///APC10/DOC domain+++IPR014722///Ribosomal protein L2, domain 2+++IPR001373///Cullin, N-terminal+++IPR016158///Cullin homology domain+++IPR031223///Cullin-7","[CUL7_HUMAN|Reviewed]RecName: Full=Cullin-7; Short=CUL-7;+++[L8E835_HUMAN|Unreviewed]SubName: Full=Alternative protein CUL7 {ECO:0000313|EMBL:CCQ43460.1};"]
[9821,"'RB1CC1'",532,728,630,"04140///Autophagy - animal+++04211///Longevity regulating pathway",{"$nulls":3},"GO:0034045///phagophore assembly site membrane+++GO:1990316///Atg1/ULK1 kinase complex+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0000407///phagophore assembly site+++GO:0005789///endoplasmic reticulum membrane+++GO:0005764///lysosome+++GO:0005737///cytoplasm+++GO:0031965///nuclear membrane+++GO:0019898///extrinsic component of membrane","GO:0032947///protein-containing complex scaffold activity+++GO:0005515///protein binding+++GO:0019901///protein kinase binding","GO:2001237///negative regulation of extrinsic apoptotic signaling pathway+++GO:0007507///heart development+++GO:0043066///negative regulation of apoptotic process+++GO:0000045///autophagosome assembly+++GO:0030242///autophagy of peroxisome+++GO:0001934///positive regulation of protein phosphorylation+++GO:0034727///piecemeal microautophagy of the nucleus+++GO:0001889///liver development+++GO:0000422///autophagy of mitochondrion+++GO:0016241///regulation of macroautophagy+++GO:0061709///reticulophagy+++GO:0006914///autophagy+++GO:0007049///cell cycle+++GO:0061723///glycophagy+++GO:0016236///macroautophagy+++GO:0045793///positive regulation of cell size+++GO:0046330///positive regulation of JNK cascade","IPR019460///Autophagy-related protein 11, C-terminal+++IPR040040///Autophagy-related protein 11+++IPR029071///Ubiquitin-like domain superfamily","[RBCC1_HUMAN|Reviewed]RecName: Full=RB1-inducible coiled-coil protein 1; AltName: Full=FAK family kinase-interacting protein of 200 kDa; Short=FIP200;+++[E5RH44_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429918}; Flags: Fragment;+++[E5RH63_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429879}; Flags: Fragment;+++[E5RHX0_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429611}; Flags: Fragment;+++[E5RJC1_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000429115};+++[H0YC28_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430792}; Flags: Fragment;+++[H0YC30_HUMAN|Unreviewed]SubName: Full=RB1-inducible coiled-coil protein 1 {ECO:0000313|Ensembl:ENSP00000430809}; Flags: Fragment;"]
[9823,"'ARMCX2'",816,848,832,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane",null,"GO:0034613///cellular protein localization+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR016024///Armadillo-type fold+++IPR011989///Armadillo-like helical+++IPR000225///Armadillo+++IPR006911///Armadillo repeat-containing domain","[ARMX2_HUMAN|Reviewed]RecName: Full=Armadillo repeat-containing X-linked protein 2; AltName: Full=ARM protein lost in epithelial cancers on chromosome X 2; Short=Protein ALEX2;+++[A0A024RCG7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2, isoform CRA_a {ECO:0000313|EMBL:EAX02889.1};+++[A0A0B4J1X4_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000393778}; Flags: Fragment;+++[A0A1B0GXK8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000415490}; Flags: Fragment;+++[A8K5M7_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76303, highly similar to Homo sapiens armadillo repeat containing, X-linked 2 (ARMCX2), mRNA {ECO:0000313|EMBL:BAF84031.1};+++[Q5H9D7_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42024.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000405376}; Flags: Fragment;+++[Q5H9D8_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42023.1}; Flags: Fragment;+++[Q5H9E0_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42021.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000410151}; Flags: Fragment;+++[Q5H9E1_HUMAN|Unreviewed]SubName: Full=Armadillo repeat containing, X-linked 2 {ECO:0000313|EMBL:CAI42020.1}; SubName: Full=Armadillo repeat-containing X-linked protein 2 {ECO:0000313|Ensembl:ENSP00000412481}; Flags: Fragment;"]
[9824,"'ARHGAP11A'",7.62,26,16.81,{"$nulls":4},"GO:0005829///cytosol","GO:0005096///GTPase activator activity","GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007165///signal transduction","IPR008936///Rho GTPase activation protein+++IPR000198///Rho GTPase-activating protein domain","[RHGBA_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 11A; AltName: Full=Rho-type GTPase-activating protein 11A;+++[A0A2X0SFK9_HUMAN|Unreviewed]SubName: Full=ARHGAP11A {ECO:0000313|EMBL:SPT35684.1}; Flags: Fragment;+++[H3BQ41_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000455593}; Flags: Fragment;+++[H3BR51_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 11A {ECO:0000313|Ensembl:ENSP00000456078};"]
[9825,"'SPATA2'",341,372,356.5,"04217///Necroptosis",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0001650///fibrillar center","GO:0005515///protein binding+++GO:0003674///molecular_function","GO:0007283///spermatogenesis+++GO:0012501///programmed cell death+++GO:0007275///multicellular organism development+++GO:0050727///regulation of inflammatory response+++GO:0060544///regulation of necroptotic process+++GO:1990108///protein linear deubiquitination+++GO:0010803///regulation of tumor necrosis factor-mediated signaling pathway+++GO:0070536///protein K63-linked deubiquitination","IPR029744///Spermatogenesis-associated protein 2","[SPAT2_HUMAN|Reviewed]RecName: Full=Spermatogenesis-associated protein 2 {ECO:0000303|PubMed:27307491, ECO:0000303|PubMed:27458237};+++[A8K0S9_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78311, highly similar to Homo sapiens spermatogenesis associated 2 (SPATA2), mRNA {ECO:0000313|EMBL:BAF82333.1};+++[B4DID4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50158, highly similar to Spermatogenesis-associated protein 2 {ECO:0000313|EMBL:BAG58446.1};+++[L8E7J6_HUMAN|Unreviewed]SubName: Full=Alternative protein SPATA2 {ECO:0000313|EMBL:CCQ43104.1};"]
[9826,"'ARHGEF11'",685,681,683,"05200///Pathways in cancer+++04928///Parathyroid hormone synthesis, secretion and action+++04270///Vascular smooth muscle contraction+++05163///Human cytomegalovirus infection",{"$nulls":3},"GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0005515///protein binding+++GO:0005096///GTPase activator activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0001664///G protein-coupled receptor binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007266///Rho protein signal transduction+++GO:0030010///establishment of cell polarity+++GO:0043547///positive regulation of GTPase activity+++GO:0006941///striated muscle contraction+++GO:0001558///regulation of cell growth+++GO:0043065///positive regulation of apoptotic process+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","IPR035899///Dbl homology (DH) domain superfamily+++IPR001849///Pleckstrin homology domain+++IPR015212///Regulator of G protein signalling-like domain+++IPR016137///RGS domain+++IPR000219///Dbl homology (DH) domain+++IPR011993///PH-like domain superfamily+++IPR037889///Rho guanine nucleotide exchange factor 11, RGS domain+++IPR037803///Rho guanine nucleotide exchange factor 11, PH domain+++IPR036034///PDZ superfamily+++IPR036305///RGS domain superfamily+++IPR032919///Rho guanine nucleotide exchange factor 11+++IPR001478///PDZ domain","[ARHGB_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 11; AltName: Full=PDZ-RhoGEF;+++[A0A2X0SFB0_HUMAN|Unreviewed]SubName: Full=ARHGEF11 {ECO:0000313|EMBL:SPT35722.1}; Flags: Fragment;"]
[9827,"'RGP1'",123,245,184,{"$nulls":4},"GO:0005886///plasma membrane+++GO:0034066///RIC1-RGP1 guanyl-nucleotide exchange factor complex+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0032588///trans-Golgi network membrane+++GO:0000139///Golgi membrane+++GO:0005829///cytosol","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0017137///Rab GTPase binding","GO:1903363///negative regulation of cellular protein catabolic process+++GO:0043547///positive regulation of GTPase activity+++GO:0042147///retrograde transport, endosome to Golgi","IPR014848///Reduced growth phenotype protein 1","[RGP1_HUMAN|Reviewed]RecName: Full=RAB6A-GEF complex partner protein 2 {ECO:0000305}; AltName: Full=Retrograde Golgi transport protein RGP1 homolog {ECO:0000250|UniProtKB:P16664};+++[A8K0K1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ76996 {ECO:0000313|EMBL:BAF82255.1};"]
[9828,"'ARHGEF17'",1405,1869,1637,{"$nulls":4},"GO:0005829///cytosol","GO:0005085///guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity","GO:0030036///actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0043065///positive regulation of apoptotic process+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007186///G protein-coupled receptor signaling pathway","IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR011993///PH-like domain superfamily+++IPR036322///WD40-repeat-containing domain superfamily+++IPR000219///Dbl homology (DH) domain+++IPR039919///Rho guanine nucleotide exchange factor 10/17+++IPR039917///Rho guanine nucleotide exchange factor 17+++IPR035899///Dbl homology (DH) domain superfamily","[ARHGH_HUMAN|Reviewed]RecName: Full=Rho guanine nucleotide exchange factor 17; AltName: Full=164 kDa Rho-specific guanine-nucleotide exchange factor; Short=p164-RhoGEF; Short=p164RhoGEF; AltName: Full=Tumor endothelial marker 4;+++[A0A2R8Y4D7_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000493940};+++[A0A2X0TVV1_HUMAN|Unreviewed]SubName: Full=ARHGEF17 {ECO:0000313|EMBL:SPT35726.1}; Flags: Fragment;+++[H0YFZ8_HUMAN|Unreviewed]SubName: Full=Rho guanine nucleotide exchange factor 17 {ECO:0000313|Ensembl:ENSP00000441135}; Flags: Fragment;"]
[9829,"'DNAJC6'",87,112,99.5,"04144///Endocytosis",{"$nulls":3},"GO:0045202///synapse+++GO:0098793///presynapse+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0014069///postsynaptic density+++GO:0031982///vesicle+++GO:0043231///intracellular membrane-bounded organelle","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0030276///clathrin binding+++GO:0017124///SH3 domain binding+++GO:0004725///protein tyrosine phosphatase activity","GO:2000369///regulation of clathrin-dependent endocytosis+++GO:0061024///membrane organization+++GO:0006470///protein dephosphorylation+++GO:0072583///clathrin-dependent endocytosis+++GO:0006898///receptor-mediated endocytosis+++GO:0016191///synaptic vesicle uncoating+++GO:0072318///clathrin coat disassembly+++GO:0035335///peptidyl-tyrosine dephosphorylation","IPR014020///Tensin phosphatase, C2 domain+++IPR001623///DnaJ domain+++IPR029023///Tensin-type phosphatase domain+++IPR036869///Chaperone J-domain superfamily+++IPR029021///Protein-tyrosine phosphatase-like","[AUXI_HUMAN|Reviewed]RecName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000305}; EC=3.1.3.48; AltName: Full=DnaJ homolog subfamily C member 6 {ECO:0000312|HGNC:HGNC:15469};+++[L0N9S0_HUMAN|Unreviewed]SubName: Full=DnaJ (Hsp40) homolog, subfamily C, member 6 {ECO:0000313|EMBL:CCE46052.1}; Flags: Fragment;+++[S4R305_HUMAN|Unreviewed]SubName: Full=Putative tyrosine-protein phosphatase auxilin {ECO:0000313|Ensembl:ENSP00000473821}; Flags: Fragment;"]
[9830,"'TRIM14'",1171,1641.31,1406.155,{"$nulls":4},"GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0016020///membrane","GO:0008270///zinc ion binding+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0002376///immune system process+++GO:0032897///negative regulation of viral transcription+++GO:0051092///positive regulation of NF-kappaB transcription factor activity+++GO:0051091///positive regulation of DNA-binding transcription factor activity+++GO:0045087///innate immune response","IPR000315///B-box-type zinc finger+++IPR006574///SPRY-associated+++IPR003877///SPRY domain+++IPR001870///B30.2/SPRY domain+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily+++IPR003879///Butyrophylin-like, SPRY domain","[TRI14_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 14;+++[A0A024R143_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_c {ECO:0000313|EMBL:EAW58876.1};+++[A0A024R165_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing 14, isoform CRA_a {ECO:0000313|EMBL:EAW58878.1};+++[F2Z2M2_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 14 {ECO:0000313|Ensembl:ENSP00000428805};"]
[9831,"'ZNF623'",122,168,145,"00760///Nicotinate and nicotinamide metabolism+++01100///Metabolic pathways","H00480///Non-syndromic X-linked mental retardation+++H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)",null,"R01724///5-phospho-alpha-D-ribose 1-diphosphate:nicotinate ligase (ADP, diphosphate-forming) Nicotinate D-ribonucleotide + Diphosphate + ADP + Orthophosphate <=> Nicotinate + 5-Phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + H+","GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZN623_HUMAN|Reviewed]RecName: Full=Zinc finger protein 623;+++[A0A0A0MT18_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000411139};+++[A0A0J9YW98_HUMAN|Unreviewed]SubName: Full=HCG31704 {ECO:0000313|EMBL:EAW82216.1}; SubName: Full=Zinc finger protein 623 {ECO:0000313|Ensembl:ENSP00000487869};"]
[9832,"'JAKMIP2'",19.01,19,19.005,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus","GO:0005515///protein binding+++GO:0008017///microtubule binding+++GO:0019900///kinase binding",null,"IPR031994///Janus kinase and microtubule-interacting protein, C-terminal domain+++IPR024836///Janus kinase and microtubule-interacting protein","[JKIP2_HUMAN|Reviewed]RecName: Full=Janus kinase and microtubule-interacting protein 2; AltName: Full=CTCL tumor antigen HD-CL-04; AltName: Full=Neuroendocrine long coiled-coil protein 1;+++[Q05DV4_HUMAN|Unreviewed]SubName: Full=JAKMIP2 protein {ECO:0000313|EMBL:AAH03189.1}; Flags: Fragment;"]
[9833,"'MELK'",11,17,14,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005938///cell cortex+++GO:0005886///plasma membrane+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005509///calcium ion binding+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity+++GO:0008289///lipid binding+++GO:0005524///ATP binding+++GO:0004715///non-membrane spanning protein tyrosine kinase activity+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0000166///nucleotide binding","GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0008631///intrinsic apoptotic signaling pathway in response to oxidative stress+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0030097///hemopoiesis+++GO:0016310///phosphorylation+++GO:0006915///apoptotic process+++GO:0046777///protein autophosphorylation+++GO:0043065///positive regulation of apoptotic process+++GO:0008283///cell proliferation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0007049///cell cycle+++GO:0061351///neural precursor cell proliferation","IPR001772///Kinase associated domain 1 (KA1)+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily+++IPR034673///Maternal embryonic leucine zipper kinase, catalytic domain+++IPR028375///KA1 domain/Ssp2, C-terminal+++IPR008271///Serine/threonine-protein kinase, active site","[MELK_HUMAN|Reviewed]RecName: Full=Maternal embryonic leucine zipper kinase; Short=hMELK; EC=2.7.11.1; AltName: Full=Protein kinase Eg3; Short=pEg3 kinase; AltName: Full=Protein kinase PK38; Short=hPK38; AltName: Full=Tyrosine-protein kinase MELK; EC=2.7.10.2;+++[A0A0D9SFB9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486459};+++[A0A0D9SFF9_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486558};+++[A0A0D9SFL8_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000486717};+++[A0A0D9SGI4_HUMAN|Unreviewed]SubName: Full=Maternal embryonic leucine zipper kinase {ECO:0000313|Ensembl:ENSP00000487536}; Flags: Fragment;+++[B7Z1G6_HUMAN|Unreviewed]RecName: Full=Non-specific serine/threonine protein kinase {ECO:0000256|SAAS:SAAS00804148}; EC=2.7.11.1 {ECO:0000256|SAAS:SAAS00804148};"]
[9836,"'LCMT2'",135,140,137.5,{"$nulls":3},"R10586///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-carboxypropyl]wyosine37-O}-methyltransferase   7-[(3S)-(3-Amino-3-carboxypropyl)]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine <=> 7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-homocysteine+++R10587///S-adenosyl-L-methionine:tRNA(Phe) {7-[(3S)-3-amino-3-(methoxycarbonyl)propyl]wyosine37-N}-methyltransferase (carbon dioxide-adding)   7-[(3S)-3-Amino-3-(methoxycarbonyl)propyl]wyosine in tRNA(Phe) + S-Adenosyl-L-methionine + CO2 <=> Wybutosine in tRNA(Phe) + S-Adenosyl-L-homocysteine","GO:0005737///cytoplasm","GO:0008168///methyltransferase activity+++GO:0018423///protein C-terminal leucine carboxyl O-methyltransferase activity+++GO:0016740///transferase activity+++GO:0005515///protein binding+++GO:0008175///tRNA methyltransferase activity","GO:0008033///tRNA processing+++GO:0006400///tRNA modification+++GO:0030488///tRNA methylation+++GO:0032259///methylation+++GO:0031591///wybutosine biosynthetic process+++GO:0006481///C-terminal protein methylation","IPR029063///S-adenosyl-L-methionine-dependent methyltransferase+++IPR015915///Kelch-type beta propeller+++IPR007213///Methyltransferase Ppm1/Ppm2/Tcmp","[TYW4_HUMAN|Reviewed]RecName: Full=tRNA wybutosine-synthesizing protein 4; Short=tRNA yW-synthesizing protein 4; EC=2.1.1.290; EC=2.3.1.231; AltName: Full=Leucine carboxyl methyltransferase 2; AltName: Full=tRNA(Phe) (7-(3-amino-3-(methoxycarbonyl)propyl)wyosine(37)-N)-methoxycarbonyltransferase; AltName: Full=tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-O)-methyltransferase;+++[H3BU01_HUMAN|Unreviewed]SubName: Full=tRNA wybutosine-synthesizing protein 4 {ECO:0000313|Ensembl:ENSP00000457403};"]
[9837,"'GINS1'",16,20,18,"04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00286///GINS complex",null,"GO:0005634///nucleus+++GO:0000811///GINS complex+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0043138///3'-5' DNA helicase activity","GO:0006271///DNA strand elongation involved in DNA replication+++GO:0001833///inner cell mass cell proliferation+++GO:1902983///DNA strand elongation involved in mitotic DNA replication+++GO:0032508///DNA duplex unwinding+++GO:0006260///DNA replication","IPR036224///GINS, helical bundle-like domain superfamily+++IPR005339///GINS complex, subunit Psf1","[PSF1_HUMAN|Reviewed]RecName: Full=DNA replication complex GINS protein PSF1; AltName: Full=GINS complex subunit 1;+++[L8ECJ2_HUMAN|Unreviewed]SubName: Full=Alternative protein GINS1 {ECO:0000313|EMBL:CCQ43662.1};"]
[9839,"'ZEB2'",298,384,341,"05206///MicroRNAs in cancer","H00961///Posterior polymorphous corneal dystrophy (PPCD)+++H00908///Mowat-Wilson syndrome+++H00960///Fuchs corneal dystrophy (FECD)",null,null,"GO:0005730///nucleolus+++GO:0005829///cytosol+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0043565///sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0019208///phosphatase regulator activity+++GO:0070412///R-SMAD binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0021957///corticospinal tract morphogenesis+++GO:0048023///positive regulation of melanin biosynthetic process+++GO:0030177///positive regulation of Wnt signaling pathway+++GO:0021766///hippocampus development+++GO:0097324///melanocyte migration+++GO:0001755///neural crest cell migration+++GO:0050772///positive regulation of axonogenesis+++GO:0021540///corpus callosum morphogenesis+++GO:0048066///developmental pigmentation+++GO:0043507///positive regulation of JUN kinase activity+++GO:1902748///positive regulation of lens fiber cell differentiation+++GO:0048668///collateral sprouting+++GO:0048598///embryonic morphogenesis+++GO:0001756///somitogenesis+++GO:0001843///neural tube closure+++GO:0061373///mammillary axonal complex development+++GO:1903056///regulation of melanosome organization+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0021846///cell proliferation in forebrain+++GO:0007399///nervous system development+++GO:0045636///positive regulation of melanocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007417///central nervous system development","IPR013087///Zinc finger C2H2-type+++IPR008598///Drought induced 19 protein type, zinc-binding domain+++IPR036236///Zinc finger C2H2 superfamily+++IPR001356///Homeobox domain+++IPR009057///Homeobox-like domain superfamily","[ZEB2_HUMAN|Reviewed]RecName: Full=Zinc finger E-box-binding homeobox 2; AltName: Full=Smad-interacting protein 1; Short=SMADIP1; AltName: Full=Zinc finger homeobox protein 1b;+++[A0A0D9SF71_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486341};+++[A0A0D9SF74_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000486346}; Flags: Fragment;+++[A0A0D9SG93_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487261};+++[A0A0D9SGG5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000487476}; Flags: Fragment;+++[A0A1B0GTH3_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000489701}; Flags: Fragment;+++[A0A1B0GUM8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490175};+++[A0A1B0GV02_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490317};+++[A0A1B0GVV8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490673};+++[A0A1B0GW50_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490776};+++[A0A1B0GWA7_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490851};+++[A0A1B0GWI0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490934};+++[A0A1W2PS25_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000492572}; Flags: Fragment;+++[A0A1X7SC99_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000490293}; Flags: Fragment;+++[A0A2R8YDQ8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000494820}; Flags: Fragment;+++[A0JP08_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|EMBL:AAI27102.1, ECO:0000313|Ensembl:ENSP00000302501};+++[C9JU62_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000400993}; Flags: Fragment;+++[C9JUQ1_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000399451}; Flags: Fragment;+++[E7ESP8_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000376601}; Flags: Fragment;+++[E7EUW9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000395496}; Flags: Fragment;+++[E7EVG9_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000387256}; Flags: Fragment;+++[H7C0G0_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000394777};+++[Q53TD9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93276.1}; Flags: Fragment;+++[Q53TG0_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein ZFHX1B {ECO:0000313|EMBL:AAX93269.1}; Flags: Fragment;+++[Q60F94_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60928.1};+++[Q60F95_HUMAN|Unreviewed]SubName: Full=Smad interacting-protein 1 {ECO:0000313|EMBL:BAD60927.1};+++[Q9H4F4_HUMAN|Unreviewed]SubName: Full=Survival interacting protein 1 {ECO:0000313|EMBL:CAC16171.1}; Flags: Fragment;+++[U3KPV5_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475267}; Flags: Fragment;+++[U3KPX6_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475329};+++[U3KQ33_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475502};+++[U3KQ51_HUMAN|Unreviewed]SubName: Full=Zinc finger E-box-binding homeobox 2 {ECO:0000313|Ensembl:ENSP00000475553};"]
[984,"'CDK11B'",938.4,834.28,886.34,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0005515///protein binding+++GO:0016301///kinase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004672///protein kinase activity","GO:0000278///mitotic cell cycle+++GO:0007049///cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0006355///regulation of transcription, DNA-templated+++GO:0016310///phosphorylation+++GO:0050684///regulation of mRNA processing+++GO:0001558///regulation of cell growth+++GO:0006468///protein phosphorylation+++GO:0006915///apoptotic process","IPR011009///Protein kinase-like domain superfamily+++IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site","[CD11B_HUMAN|Reviewed]RecName: Full=Cyclin-dependent kinase 11B; EC=2.7.11.22; AltName: Full=Cell division cycle 2-like protein kinase 1; Short=CLK-1; AltName: Full=Cell division protein kinase 11B; AltName: Full=Galactosyltransferase-associated protein kinase p58/GTA; AltName: Full=PITSLRE serine/threonine-protein kinase CDC2L1; AltName: Full=p58 CLK-1;+++[A0A087WYI9_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000481846};+++[A0A087X1I0_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000484222};+++[A0A0D9SEI3_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485705};+++[A0A0D9SEN2_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485849};+++[A0A0D9SER5_HUMAN|Unreviewed]SubName: Full=Cyclin-dependent kinase 11B {ECO:0000313|Ensembl:ENSP00000485937};+++[A4VCI5_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAI39778.1}; Flags: Fragment;+++[B4DII1_HUMAN|Unreviewed]SubName: Full=cDNA FLJ59025, moderately similar to PITSLRE serine/threonine-protein kinaseCDC2L1 {ECO:0000313|EMBL:BAG58493.1};+++[Q6PK02_HUMAN|Unreviewed]SubName: Full=CDC2L1 protein {ECO:0000313|EMBL:AAH09375.1}; Flags: Fragment;"]
[9840,"'TESPA1'",0,1,0.5,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0008180///COP9 signalosome","GO:0005102///signaling receptor binding","GO:0010387///COP9 signalosome assembly+++GO:0033089///positive regulation of T cell differentiation in thymus+++GO:0050862///positive regulation of T cell receptor signaling pathway","IPR029325///ITPR-interacting domain+++IPR026647///Protein TESPA1","[TESP1_HUMAN|Reviewed]RecName: Full=Protein TESPA1; AltName: Full=Thymocyte-expressed positive selection-associated protein 1;+++[A0A024RB00_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_a {ECO:0000313|EMBL:EAW96798.1};+++[A0A024RB73_HUMAN|Unreviewed]SubName: Full=HCG21937, isoform CRA_c {ECO:0000313|EMBL:EAW96800.1};+++[E9PHY9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436635}; Flags: Fragment;+++[E9PIN8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000435734}; Flags: Fragment;+++[E9PIT9_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433895}; Flags: Fragment;+++[E9PM24_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000433187}; Flags: Fragment;+++[E9PN46_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434811};+++[E9PPW8_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436286}; Flags: Fragment;+++[H0YDP3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000434039}; Flags: Fragment;+++[H0YEX3_HUMAN|Unreviewed]SubName: Full=Protein TESPA1 {ECO:0000313|Ensembl:ENSP00000436753}; Flags: Fragment;"]
[9841,"'ZBTB24'",123.2,166.95,145.075,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm","GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0005515///protein binding","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0002244///hematopoietic progenitor cell differentiation+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR011333///SKP1/BTB/POZ domain superfamily+++IPR000210///BTB/POZ domain+++IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type","[ZBT24_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 24; AltName: Full=Zinc finger protein 450;"]
[9842,"'PLEKHM1'",1962,2084,2023,{"$nulls":4},"GO:0043231///intracellular membrane-bounded organelle+++GO:0005768///endosome+++GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0010008///endosome membrane+++GO:0005764///lysosome+++GO:0005765///lysosomal membrane+++GO:0016020///membrane","GO:0046872///metal ion binding","GO:0006914///autophagy+++GO:0015031///protein transport+++GO:0035556///intracellular signal transduction+++GO:0032418///lysosome localization+++GO:0045780///positive regulation of bone resorption+++GO:1900029///positive regulation of ruffle assembly","IPR002219///Protein kinase C-like, phorbol ester/diacylglycerol-binding domain+++IPR001849///Pleckstrin homology domain+++IPR037213///RUN domain superfamily+++IPR004012///RUN domain+++IPR025258///Putative zinc-RING and/or ribbon+++IPR011993///PH-like domain superfamily","[PKHM1_HUMAN|Reviewed]RecName: Full=Pleckstrin homology domain-containing family M member 1; Short=PH domain-containing family M member 1; AltName: Full=162 kDa adapter protein; Short=AP162;+++[J3KRL8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462065}; Flags: Fragment;+++[J3KRU0_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462160};+++[J3KS30_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000462282};+++[K7EII8_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000464766};+++[K7EMP2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000466589}; Flags: Fragment;+++[K7EPF2_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467356}; Flags: Fragment;+++[K7EQ68_HUMAN|Unreviewed]SubName: Full=Pleckstrin homology domain-containing family M member 1 {ECO:0000313|Ensembl:ENSP00000467695}; Flags: Fragment;"]
[9843,"'HEPH'",250,293,271.5,"00860///Porphyrin and chlorophyll metabolism+++04978///Mineral absorption",null,null,"R00078///Fe(II):oxygen oxidoreductase; Fe2+:oxygen   Oxygen + 4 Fe2+ + 4 H+ <=> 4 Fe3+ + 2 H2O","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005622///intracellular+++GO:0016323///basolateral plasma membrane+++GO:0005886///plasma membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0005615///extracellular space","GO:0016491///oxidoreductase activity+++GO:0016722///oxidoreductase activity, oxidizing metal ions+++GO:0046872///metal ion binding+++GO:0008198///ferrous iron binding+++GO:0005507///copper ion binding+++GO:0004322///ferroxidase activity","GO:0006879///cellular iron ion homeostasis+++GO:0055114///oxidation-reduction process+++GO:0006825///copper ion transport+++GO:0006811///ion transport+++GO:0006826///iron ion transport+++GO:0055072///iron ion homeostasis","IPR011707///Multicopper oxidase, type 3+++IPR008972///Cupredoxin+++IPR002355///Multicopper oxidase, copper-binding site+++IPR027154///Hephaestin+++IPR011706///Multicopper oxidase, type 2+++IPR033138///Multicopper oxidases, conserved site","[HEPH_HUMAN|Reviewed]RecName: Full=Hephaestin; EC=1.-.-.-; Flags: Precursor;+++[A0A0C4DG76_HUMAN|Unreviewed]SubName: Full=Hephaestin, isoform CRA_c {ECO:0000313|EMBL:EAX05387.1};+++[E7ES21_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000413211};+++[F8WBZ8_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000392319};+++[Q1HE23_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|EMBL:ABF47089.1};+++[Q5JZ07_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000396907}; Flags: Fragment;+++[Q5JZ08_HUMAN|Unreviewed]SubName: Full=Hephaestin {ECO:0000313|Ensembl:ENSP00000398078}; Flags: Fragment;"]
[9844,"'ELMO1'",143,129,136,"05100///Bacterial invasion of epithelial cells+++05131///Shigellosis+++04062///Chemokine signaling pathway",{"$nulls":3},"GO:0005829///cytosol+++GO:0032045///guanyl-nucleotide exchange factor complex+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm","GO:0017124///SH3 domain binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0050690///regulation of defense response to virus by virus+++GO:0006909///phagocytosis+++GO:0030036///actin cytoskeleton organization+++GO:0016477///cell migration+++GO:0030029///actin filament-based process+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0048870///cell motility+++GO:0006915///apoptotic process+++GO:0016601///Rac protein signal transduction+++GO:0006911///phagocytosis, engulfment","IPR030715///Engulfment and cell motility protein 1+++IPR011993///PH-like domain superfamily+++IPR011989///Armadillo-like helical+++IPR024574///Domain of unknown function DUF3361+++IPR016024///Armadillo-type fold+++IPR001849///Pleckstrin homology domain+++IPR006816///ELMO domain","[ELMO1_HUMAN|Reviewed]RecName: Full=Engulfment and cell motility protein 1; AltName: Full=Protein ced-12 homolog;+++[A4D1X5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility 1 (Ced-12 homolog, C. elegans) {ECO:0000313|EMBL:EAL23978.1}; SubName: Full=Engulfment and cell motility 1, isoform CRA_c {ECO:0000313|EMBL:EAW94077.1}; SubName: Full=cDNA FLJ77700, highly similar to Homo sapiens engulfment and cell motility 1 (ELMO1), transcript variant 1, mRNA {ECO:0000313|EMBL:BAF84473.1};+++[C9IZR8_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000406610}; Flags: Fragment;+++[C9J5X3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000397857}; Flags: Fragment;+++[C9JB20_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000391734}; Flags: Fragment;+++[C9JIW2_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000416090}; Flags: Fragment;+++[H7C0N5_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000395933}; Flags: Fragment;+++[H7C0S6_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000396465}; Flags: Fragment;+++[H7C3P3_HUMAN|Unreviewed]SubName: Full=Engulfment and cell motility protein 1 {ECO:0000313|Ensembl:ENSP00000413108}; Flags: Fragment;"]
[9846,"'GAB2'",752,1137,944.5,"05220///Chronic myeloid leukemia+++04666///Fc gamma R-mediated phagocytosis+++04664///Fc epsilon RI signaling pathway+++04072///Phospholipase D signaling pathway+++04071///Sphingolipid signaling pathway+++04380///Osteoclast differentiation+++04014///Ras signaling pathway","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0043325///phosphatidylinositol-3,4-bisphosphate binding+++GO:0016303///1-phosphatidylinositol-3-kinase activity+++GO:0005547///phosphatidylinositol-3,4,5-trisphosphate binding+++GO:0005515///protein binding+++GO:0005068///transmembrane receptor protein tyrosine kinase adaptor activity","GO:0007169///transmembrane receptor protein tyrosine kinase signaling pathway+++GO:0030316///osteoclast differentiation+++GO:0008284///positive regulation of cell proliferation+++GO:0048015///phosphatidylinositol-mediated signaling+++GO:0038095///Fc-epsilon receptor signaling pathway+++GO:0019221///cytokine-mediated signaling pathway+++GO:0043306///positive regulation of mast cell degranulation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process+++GO:0007411///axon guidance","IPR011993///PH-like domain superfamily+++IPR001849///Pleckstrin homology domain","[GAB2_HUMAN|Reviewed]RecName: Full=GRB2-associated-binding protein 2; AltName: Full=GRB2-associated binder 2; AltName: Full=Growth factor receptor bound protein 2-associated protein 2; AltName: Full=pp100;+++[E9PJ26_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000431868}; Flags: Fragment;+++[E9PJE2_HUMAN|Unreviewed]SubName: Full=GRB2-associated-binding protein 2 {ECO:0000313|Ensembl:ENSP00000433762}; Flags: Fragment;"]
[9847,"'C2CD5'",132,162,147,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005829///cytosol+++GO:0030659///cytoplasmic vesicle membrane+++GO:0005886///plasma membrane+++GO:0005938///cell cortex+++GO:0005737///cytoplasm+++GO:0031410///cytoplasmic vesicle+++GO:0042995///cell projection+++GO:0001726///ruffle+++GO:0032587///ruffle membrane+++GO:0005815///microtubule organizing center","GO:0005509///calcium ion binding+++GO:0008289///lipid binding+++GO:0005544///calcium-dependent phospholipid binding","GO:0006906///vesicle fusion+++GO:0038028///insulin receptor signaling pathway via phosphatidylinositol 3-kinase+++GO:0090314///positive regulation of protein targeting to membrane+++GO:0046326///positive regulation of glucose import+++GO:0010828///positive regulation of glucose transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0015031///protein transport+++GO:0065002///intracellular protein transmembrane transport+++GO:0031340///positive regulation of vesicle fusion+++GO:0032869///cellular response to insulin stimulus","IPR038983///C2 domain-containing protein 5+++IPR037785///C2CD5, C2 domain+++IPR000008///C2 domain+++IPR035892///C2 domain superfamily","[C2CD5_HUMAN|Reviewed]RecName: Full=C2 domain-containing protein 5; AltName: Full=C2 domain-containing phosphoprotein of 138 kDa;+++[A0A024RB03_HUMAN|Unreviewed]SubName: Full=KIAA0528, isoform CRA_b {ECO:0000313|EMBL:EAW96475.1};+++[B7ZLK1_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43860.1};+++[B7ZLK2_HUMAN|Unreviewed]SubName: Full=KIAA0528 protein {ECO:0000313|EMBL:AAI43861.1};+++[H0YFC4_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000437935}; Flags: Fragment;+++[H0YFE9_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000438256}; Flags: Fragment;+++[H0YGU7_HUMAN|Unreviewed]SubName: Full=C2 domain-containing protein 5 {ECO:0000313|Ensembl:ENSP00000444857}; Flags: Fragment;"]
[9848,"'MFAP3L'",521,806,663.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0005515///protein binding",null,"IPR003599///Immunoglobulin subtype+++IPR013098///Immunoglobulin I-set+++IPR036179///Immunoglobulin-like domain superfamily+++IPR013783///Immunoglobulin-like fold+++IPR003598///Immunoglobulin subtype 2+++IPR007110///Immunoglobulin-like domain+++IPR039696///Microfibril-associated glycoprotein 3-like","[MFA3L_HUMAN|Reviewed]RecName: Full=Microfibrillar-associated protein 3-like; AltName: Full=Testis development protein NYD-SP9 {ECO:0000303|Ref.1}; Flags: Precursor;+++[D6R9L7_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423549}; Flags: Fragment;+++[D6RAB5_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000422791}; Flags: Fragment;+++[D6RCC0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423802}; Flags: Fragment;+++[D6RCF0_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000423722}; Flags: Fragment;+++[D6RDM6_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000425303}; Flags: Fragment;+++[D6RGZ8_HUMAN|Unreviewed]SubName: Full=Microfibrillar-associated protein 3-like {ECO:0000313|Ensembl:ENSP00000426247}; Flags: Fragment;"]
[9849,"'ZNF518A'",53,92,72.5,"04137///Mitophagy - animal+++04140///Autophagy - animal+++04064///NF-kappa B signaling pathway+++05340///Primary immunodeficiency+++04380///Osteoclast differentiation+++04662///B cell receptor signaling pathway","H00085///Agammaglobulinemias",null,null,"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR027760///Zinc finger protein 518+++IPR013087///Zinc finger C2H2-type","[Z518A_HUMAN|Reviewed]RecName: Full=Zinc finger protein 518A;+++[A0A087WWK1_HUMAN|Unreviewed]SubName: Full=Zinc finger protein 518A {ECO:0000313|Ensembl:ENSP00000480280}; Flags: Fragment;"]
[9851,"'KIAA0753'",194,228,211,{"$nulls":4},"GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0034451///centriolar satellite+++GO:0005737///cytoplasm+++GO:0005815///microtubule organizing center","GO:0005515///protein binding","GO:0007099///centriole replication+++GO:0071539///protein localization to centrosome","IPR031447///Protein moonraker","[MOONR_HUMAN|Reviewed]RecName: Full=Protein moonraker {ECO:0000303|PubMed:26297806}; Short=MNR {ECO:0000303|PubMed:26297806}; AltName: Full=OFD1- and FOPNL-interacting protein {ECO:0000303|PubMed:26643951};+++[F6SFD5_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000444946}; Flags: Fragment;+++[I3L0P7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458247}; Flags: Fragment;+++[I3L1P2_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000458983}; Flags: Fragment;+++[I3L2A7_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000459530}; Flags: Fragment;+++[I3L341_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460156}; Flags: Fragment;+++[I3L3Y0_HUMAN|Unreviewed]SubName: Full=Protein moonraker {ECO:0000313|Ensembl:ENSP00000460816};"]
[9852,"'EPM2AIP1'",561,567,564,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding+++GO:0042802///identical protein binding","GO:0032868///response to insulin+++GO:2000467///positive regulation of glycogen (starch) synthase activity+++GO:0045725///positive regulation of glycogen biosynthetic process","IPR026630///EPM2A-interacting protein 1+++IPR026625///General transcription factor II-I-related protein","[EPMIP_HUMAN|Reviewed]RecName: Full=EPM2A-interacting protein 1; AltName: Full=Laforin-interacting protein;+++[A0A096LNL1_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485091}; Flags: Fragment;+++[A0A096LPB0_HUMAN|Unreviewed]SubName: Full=EPM2A-interacting protein 1 {ECO:0000313|Ensembl:ENSP00000485489}; Flags: Fragment;"]
[9853,"'RUSC2'",3749,4559,4154,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005829///cytosol+++GO:0031410///cytoplasmic vesicle+++GO:0005737///cytoplasm+++GO:0070062///extracellular exosome","GO:0005515///protein binding+++GO:0017137///Rab GTPase binding","GO:0008150///biological_process","IPR036028///SH3-like domain superfamily+++IPR037213///RUN domain superfamily+++IPR004012///RUN domain+++IPR001452///SH3 domain","[RUSC2_HUMAN|Reviewed]RecName: Full=Iporin; AltName: Full=Interacting protein of Rab1; AltName: Full=RUN and SH3 domain-containing protein 2;"]
[9854,"'C2CD2L'",886,901,893.5,"00510///N-Glycan biosynthesis+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome+++H00118///Congenital disorders of glycosylation (CDG) type I","M00055///N-glycan precursor biosynthesis","R05969///UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase UDP-N-acetyl-alpha-D-glucosamine + Dolichyl phosphate <=> UMP + N-Acetyl-D-glucosaminyldiphosphodolichol","GO:0005783///endoplasmic reticulum+++GO:0005789///endoplasmic reticulum membrane+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0098592///cytoplasmic side of apical plasma membrane+++GO:0016020///membrane+++GO:0032541///cortical endoplasmic reticulum","GO:0008526///phosphatidylinositol transporter activity+++GO:0008289///lipid binding+++GO:0035091///phosphatidylinositol binding+++GO:0043559///insulin binding+++GO:0005548///phospholipid transporter activity","GO:0015914///phospholipid transport+++GO:0006869///lipid transport+++GO:0035774///positive regulation of insulin secretion involved in cellular response to glucose stimulus","IPR039934///C2 domain-containing protein 2-like","[C2C2L_HUMAN|Reviewed]RecName: Full=Phospholipid transfer protein C2CD2L {ECO:0000305}; AltName: Full=C2 domain-containing protein 2-like {ECO:0000312|HGNC:HGNC:29000}; Short=C2CD2-like; AltName: Full=Transmembrane protein 24 {ECO:0000303|PubMed:28209843};+++[E9PK05_HUMAN|Unreviewed]SubName: Full=Phospholipid transfer protein C2CD2L {ECO:0000313|Ensembl:ENSP00000433600};+++[Q6DHX1_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH75832.1}; Flags: Fragment;+++[Q9BTM2_HUMAN|Unreviewed]SubName: Full=C2CD2L protein {ECO:0000313|EMBL:AAH03598.2};"]
[9855,"'FARP2'",199,176,187.5,"04015///Rap1 signaling pathway+++04520///Adherens junction",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0030676///Rac guanyl-nucleotide exchange factor activity+++GO:0005089///Rho guanyl-nucleotide exchange factor activity+++GO:0008092///cytoskeletal protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0030316///osteoclast differentiation+++GO:0033623///regulation of integrin activation+++GO:0031532///actin cytoskeleton reorganization+++GO:0071526///semaphorin-plexin signaling pathway+++GO:0022405///hair cycle process+++GO:0016601///Rac protein signal transduction+++GO:0071800///podosome assembly+++GO:0007155///cell adhesion+++GO:0035023///regulation of Rho protein signal transduction+++GO:0016322///neuron remodeling","IPR014352///FERM/acyl-CoA-binding protein superfamily+++IPR035963///FERM superfamily, second domain+++IPR014847///FERM adjacent (FA)+++IPR000299///FERM domain+++IPR018980///FERM, C-terminal PH-like domain+++IPR018979///FERM, N-terminal+++IPR019749///Band 4.1 domain+++IPR000219///Dbl homology (DH) domain+++IPR019748///FERM central domain+++IPR035899///Dbl homology (DH) domain superfamily+++IPR011993///PH-like domain superfamily+++IPR029071///Ubiquitin-like domain superfamily+++IPR019747///FERM conserved site+++IPR000798///Ezrin/radixin/moesin-like+++IPR001849///Pleckstrin homology domain","[FARP2_HUMAN|Reviewed]RecName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2; AltName: Full=FERM domain-including RhoGEF; Short=FIR; AltName: Full=FERM, RhoGEF and pleckstrin domain-containing protein 2; AltName: Full=Pleckstrin homology domain-containing family C member 3; Short=PH domain-containing family C member 3;+++[A0A2X0SSL3_HUMAN|Unreviewed]SubName: Full=FARP2 {ECO:0000313|EMBL:SPT35757.1}; Flags: Fragment;+++[C9JVQ5_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000393376}; Flags: Fragment;+++[C9JWM9_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000388167}; Flags: Fragment;+++[H7C210_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000403437}; Flags: Fragment;+++[H7C3E4_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000411353}; Flags: Fragment;+++[H7C3M7_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000412772}; Flags: Fragment;+++[H7C447_HUMAN|Unreviewed]SubName: Full=FERM, ARHGEF and pleckstrin domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000415474}; Flags: Fragment;"]
[9856,"'KIAA0319'",10,15,12.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0005769///early endosome+++GO:0043231///intracellular membrane-bounded organelle+++GO:0030665///clathrin-coated vesicle membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005886///plasma membrane+++GO:0031901///early endosome membrane+++GO:0016021///integral component of membrane","GO:0005515///protein binding","GO:0007399///nervous system development+++GO:2000171///negative regulation of dendrite development+++GO:0001764///neuron migration+++GO:0007275///multicellular organism development+++GO:0061024///membrane organization","IPR013980///MANSC domain+++IPR011106///Seven cysteines, N-terminal+++IPR003961///Fibronectin type III+++IPR013783///Immunoglobulin-like fold+++IPR035986///PKD domain superfamily+++IPR000601///PKD domain+++IPR002859///PKD/REJ-like domain+++IPR022409///PKD/Chitinase domain","[K0319_HUMAN|Reviewed]RecName: Full=Dyslexia-associated protein KIAA0319; Flags: Precursor;+++[A0A087X0U9_HUMAN|Unreviewed]SubName: Full=Dyslexia-associated protein KIAA0319 {ECO:0000313|Ensembl:ENSP00000483665};+++[L8E9P4_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0319 {ECO:0000313|EMBL:CCQ43461.1};"]
[9857,"'CEP350'",177,264,220.5,{"$nulls":4},"GO:0005819///spindle+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005815///microtubule organizing center+++GO:0005856///cytoskeleton+++GO:0005814///centriole+++GO:0005737///cytoplasm+++GO:0005813///centrosome+++GO:0042995///cell projection","GO:0008017///microtubule binding+++GO:0005515///protein binding","GO:0034453///microtubule anchoring","IPR025486///Domain of unknown function DUF4378+++IPR036859///CAP Gly-rich domain superfamily+++IPR000938///CAP Gly-rich domain+++IPR028750///Centrosome-associated protein 350","[CE350_HUMAN|Reviewed]RecName: Full=Centrosome-associated protein 350 {ECO:0000305}; Short=Cep350; AltName: Full=Centrosome-associated protein of 350 kDa {ECO:0000303|Ref.1};+++[A0A024R914_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 350kDa, isoform CRA_a {ECO:0000313|EMBL:EAW91073.1};+++[A2A4F6_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000350016}; Flags: Fragment;+++[E9PIK0_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000435808}; Flags: Fragment;+++[H0Y6Q4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000407044}; Flags: Fragment;+++[H0Y7F7_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000412460}; Flags: Fragment;+++[H0YD38_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000432910}; Flags: Fragment;+++[L8ECF2_HUMAN|Unreviewed]SubName: Full=Alternative protein CEP350 {ECO:0000313|EMBL:CCQ43462.1};+++[Q05D72_HUMAN|Unreviewed]SubName: Full=CEP350 protein {ECO:0000313|EMBL:AAH17847.1}; Flags: Fragment;+++[Q5T2X4_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000401608}; Flags: Fragment;+++[Q5T2X5_HUMAN|Unreviewed]SubName: Full=Centrosome-associated protein 350 {ECO:0000313|Ensembl:ENSP00000409395}; Flags: Fragment;"]
[9858,"'PPP1R26'",159,119,139,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005730///nucleolus+++GO:0005634///nucleus","GO:0004864///protein phosphatase inhibitor activity+++GO:0005515///protein binding","GO:0010923///negative regulation of phosphatase activity+++GO:0032515///negative regulation of phosphoprotein phosphatase activity","IPR026130///Protein phosphatase 1 regulatory subunit 26+++IPR031474///Protein phosphatase 1 regulatory subunit 26, N-terminal domain","[PPR26_HUMAN|Reviewed]RecName: Full=Protein phosphatase 1 regulatory subunit 26;+++[A0A024R8E9_HUMAN|Unreviewed]SubName: Full=KIAA0649, isoform CRA_a {ECO:0000313|EMBL:EAW88151.1};"]
[9859,"'CEP170'",1188,1526,1357,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0005886///plasma membrane+++GO:0120103///centriolar subdistal appendage+++GO:0005819///spindle+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005814///centriole+++GO:0005813///centrosome+++GO:0005856///cytoskeleton+++GO:0005874///microtubule","GO:0005515///protein binding",null,"IPR000253///Forkhead-associated (FHA) domain+++IPR029300///CEP170, C-terminal+++IPR026644///Centrosomal protein of 170kDa+++IPR008984///SMAD/FHA domain superfamily","[CE170_HUMAN|Reviewed]RecName: Full=Centrosomal protein of 170 kDa; Short=Cep170; AltName: Full=KARP-1-binding protein; Short=KARP1-binding protein;+++[A6H8X9_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI46791.1};+++[B2RTS4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein 170kDa {ECO:0000313|EMBL:AAI40795.1};+++[E5RFU8_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427944}; Flags: Fragment;+++[E5RG47_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427843}; Flags: Fragment;+++[E5RGW7_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430112}; Flags: Fragment;+++[E5RIH6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428400}; Flags: Fragment;+++[E5RJT5_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428183}; Flags: Fragment;+++[E7EMW0_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000427842};+++[E7EWM2_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000430142};+++[H0Y2V6_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000338161}; Flags: Fragment;+++[H0Y4T4_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000394002}; Flags: Fragment;+++[H0YB66_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428777}; Flags: Fragment;+++[H0YB92_HUMAN|Unreviewed]SubName: Full=Centrosomal protein of 170 kDa {ECO:0000313|Ensembl:ENSP00000428996}; Flags: Fragment;+++[Q6AZE1_HUMAN|Unreviewed]SubName: Full=CEP170 protein {ECO:0000313|EMBL:AAH78155.1}; Flags: Fragment;"]
[9860,"'LRIG2'",112,148.55,130.275,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0030426///growth cone+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0043025///neuronal cell body+++GO:0005615///extracellular space+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0043005///neuron projection+++GO:0005886///plasma membrane+++GO:0097708///intracellular vesicle","GO:0005102///signaling receptor binding","GO:0048681///negative regulation of axon regeneration+++GO:2000010///positive regulation of protein localization to cell surface+++GO:0010640///regulation of platelet-derived growth factor receptor signaling pathway+++GO:0010977///negative regulation of neuron projection development+++GO:2001222///regulation of neuron migration+++GO:0051045///negative regulation of membrane protein ectodomain proteolysis+++GO:0048679///regulation of axon regeneration+++GO:0060384///innervation+++GO:0007605///sensory perception of sound","IPR000483///Cysteine-rich flanking region, C-terminal+++IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily+++IPR003598///Immunoglobulin subtype 2+++IPR007110///Immunoglobulin-like domain+++IPR003599///Immunoglobulin subtype+++IPR013098///Immunoglobulin I-set+++IPR036179///Immunoglobulin-like domain superfamily+++IPR003591///Leucine-rich repeat, typical subtype+++IPR013783///Immunoglobulin-like fold","[LRIG2_HUMAN|Reviewed]RecName: Full=Leucine-rich repeats and immunoglobulin-like domains protein 2; Short=LIG-2; Flags: Precursor;"]
[9861,"'PSMD6'",673,546,609.5,"03050///Proteasome+++05169///Epstein-Barr virus infection","H00063///Spinocerebellar ataxia (SCA)","M00341///Proteasome, 19S regulatory particle (PA700)",null,"GO:0005576///extracellular region+++GO:0000502///proteasome complex+++GO:1904813///ficolin-1-rich granule lumen+++GO:0022624///proteasome accessory complex+++GO:0005829///cytosol+++GO:0005838///proteasome regulatory particle+++GO:0034774///secretory granule lumen+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0030234///enzyme regulator activity+++GO:0016887///ATPase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis+++GO:0043687///post-translational protein modification+++GO:0050790///regulation of catalytic activity+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0043312///neutrophil degranulation","IPR000717///Proteasome component (PCI) domain+++IPR035268///26S Proteasome non-ATPase regulatory subunit 6+++IPR019585///26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR011990///Tetratricopeptide-like helical domain superfamily","[PSMD6_HUMAN|Reviewed]RecName: Full=26S proteasome non-ATPase regulatory subunit 6; AltName: Full=26S proteasome regulatory subunit RPN7; AltName: Full=26S proteasome regulatory subunit S10; AltName: Full=Breast cancer-associated protein SGA-113M; AltName: Full=Phosphonoformate immuno-associated protein 4; AltName: Full=Proteasome regulatory particle subunit p44S10; AltName: Full=p42A;+++[B3KT66_HUMAN|Unreviewed]SubName: Full=Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 6, isoform CRA_c {ECO:0000313|EMBL:EAW65426.1}; SubName: Full=cDNA FLJ37740 fis, clone BRHIP2021870, highly similar to 26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|EMBL:BAG52978.1};+++[C9J0E9_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418887}; Flags: Fragment;+++[C9J7B7_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418303}; Flags: Fragment;+++[H7C531_HUMAN|Unreviewed]SubName: Full=26S proteasome non-ATPase regulatory subunit 6 {ECO:0000313|Ensembl:ENSP00000418843}; Flags: Fragment;"]
[9862,"'MED24'",1531,1658,1594.5,"04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0042809///vitamin D receptor binding+++GO:0046966///thyroid hormone receptor binding+++GO:0003712///transcription coregulator activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0038023///signaling receptor activity","GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0030521///androgen receptor signaling pathway+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045893///positive regulation of transcription, DNA-templated","IPR021429///Mediator complex, subunit Med24, N-terminal","[MED24_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 24; AltName: Full=Activator-recruited cofactor 100 kDa component; Short=ARC100; AltName: Full=Cofactor required for Sp1 transcriptional activation subunit 4; Short=CRSP complex subunit 4; AltName: Full=Mediator complex subunit 24; AltName: Full=Thyroid hormone receptor-associated protein 4; AltName: Full=Thyroid hormone receptor-associated protein complex 100 kDa component; Short=Trap100; Short=hTRAP100; AltName: Full=Vitamin D3 receptor-interacting protein complex 100 kDa component; Short=DRIP100;+++[A0A0B4J1W0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000377684}; SubName: Full=Thyroid hormone receptor associated protein 4, isoform CRA_a {ECO:0000313|EMBL:EAW60629.1};+++[B4DDR8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463751}; SubName: Full=cDNA FLJ59464, highly similar to Thyroid hormone receptor-associated proteincomplex 100 kDa component {ECO:0000313|EMBL:BAG56829.1};+++[B9TX62_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i2 {ECO:0000313|EMBL:ACB88915.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000393464}; Flags: Fragment;+++[B9TX63_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i3 {ECO:0000313|EMBL:ACB88916.1}; Flags: Fragment;+++[B9TX64_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i4 {ECO:0000313|EMBL:ACB88917.1}; Flags: Fragment;+++[B9TX65_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i5 {ECO:0000313|EMBL:ACB88918.1}; Flags: Fragment;+++[B9TX66_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i6 {ECO:0000313|EMBL:ACB88919.1}; Flags: Fragment;+++[B9TX67_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i7 {ECO:0000313|EMBL:ACB88920.1}; Flags: Fragment;+++[B9TX68_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i8 {ECO:0000313|EMBL:ACB88921.1}; Flags: Fragment;+++[B9TX69_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i9 {ECO:0000313|EMBL:ACB88922.1}; Flags: Fragment;+++[B9TX70_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i10 {ECO:0000313|EMBL:ACB88923.1}; Flags: Fragment;+++[B9TX71_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i11 {ECO:0000313|EMBL:ACB88924.1}; Flags: Fragment;+++[B9TX72_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i12 {ECO:0000313|EMBL:ACB88925.1}; Flags: Fragment;+++[B9TX73_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i13 {ECO:0000313|EMBL:ACB88926.1}; Flags: Fragment;+++[B9TX74_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i14 {ECO:0000313|EMBL:ACB88927.1}; Flags: Fragment;+++[B9TX75_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i15 {ECO:0000313|EMBL:ACB88928.1}; SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000482676};+++[B9TX76_HUMAN|Unreviewed]SubName: Full=Mediator complex subunit MED24 variant MED24_i16 {ECO:0000313|EMBL:ACB88929.1};+++[E9PFL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000392276}; Flags: Fragment;+++[F5GY88_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000440100};+++[F5H0M2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438767}; Flags: Fragment;+++[F5H2D6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000438630}; Flags: Fragment;+++[F5H3E6_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000439148};+++[F5H5K2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000443344}; Flags: Fragment;+++[H0YEG1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000435760}; Flags: Fragment;+++[J3KSL1_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462539}; Flags: Fragment;+++[J3KSU0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000462646}; Flags: Fragment;+++[J3KTL3_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463043}; Flags: Fragment;+++[J3QLC0_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463480}; Flags: Fragment;+++[J3QLC2_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463484}; Flags: Fragment;+++[J3QLF8_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463528}; Flags: Fragment;+++[J3QLV7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000463724}; Flags: Fragment;+++[J3QRH9_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 24 {ECO:0000313|Ensembl:ENSP00000464225}; Flags: Fragment;"]
[9863,"'MAGI2'",99,159,129,"04151///PI3K-Akt signaling pathway+++04015///Rap1 signaling pathway","H01657///Nephrotic syndrome",null,null,"GO:0048471///perinuclear region of cytoplasm+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005923///bicellular tight junction+++GO:0045202///synapse+++GO:0005768///endosome+++GO:0043005///neuron projection+++GO:0014069///postsynaptic density+++GO:0005770///late endosome+++GO:0032991///protein-containing complex+++GO:0036057///slit diaphragm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030425///dendrite","GO:0030159///receptor signaling complex scaffold activity+++GO:0005515///protein binding+++GO:0019902///phosphatase binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0031697///beta-1 adrenergic receptor binding+++GO:0070699///type II activin receptor binding+++GO:0070697///activin receptor binding+++GO:0016301///kinase activity+++GO:0046332///SMAD binding","GO:0007399///nervous system development+++GO:0032926///negative regulation of activin receptor signaling pathway+++GO:0072015///glomerular visceral epithelial cell development+++GO:0032516///positive regulation of phosphoprotein phosphatase activity+++GO:0010976///positive regulation of neuron projection development+++GO:0030336///negative regulation of cell migration+++GO:0002092///positive regulation of receptor internalization+++GO:0008285///negative regulation of cell proliferation+++GO:0043113///receptor clustering+++GO:0038180///nerve growth factor signaling pathway+++GO:0051898///negative regulation of protein kinase B signaling+++GO:2000809///positive regulation of synaptic vesicle clustering+++GO:0060395///SMAD protein signal transduction+++GO:0097118///neuroligin clustering involved in postsynaptic membrane assembly+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0071850///mitotic cell cycle arrest+++GO:0007165///signal transduction+++GO:0051291///protein heterooligomerization+++GO:0016310///phosphorylation+++GO:0003402///planar cell polarity pathway involved in axis elongation","IPR008144///Guanylate kinase-like domain+++IPR020590///Guanylate kinase, conserved site+++IPR001478///PDZ domain+++IPR036034///PDZ superfamily+++IPR036020///WW domain superfamily+++IPR001202///WW domain+++IPR030036///Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2+++IPR008145///Guanylate kinase/L-type calcium channel beta subunit+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[MAGI2_HUMAN|Reviewed]RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; AltName: Full=Atrophin-1-interacting protein 1; Short=AIP-1; AltName: Full=Atrophin-1-interacting protein A; AltName: Full=Membrane-associated guanylate kinase inverted 2; Short=MAGI-2;+++[A0A0D9SET0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000485970};+++[A0A0D9SEY4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486131};+++[A0A0D9SEZ7_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486154}; Flags: Fragment;+++[A0A0D9SF86_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486379}; Flags: Fragment;+++[A0A0D9SFP3_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000486774};+++[A0A0D9SFY9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487001}; Flags: Fragment;+++[A0A0D9SGF2_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487435};+++[A0A0D9SGF8_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_c {ECO:0000313|EMBL:EAW77024.1}; SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487448};+++[A0A0D9SGI1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000487526};+++[A0A0E3D6M1_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000441603};+++[A0A0U1RRH4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489533}; Flags: Fragment;+++[A0A1B0GTC0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489633};+++[A0A1B0GTH8_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000489709}; Flags: Fragment;+++[A0A1B0GUF0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490080};+++[A0A1B0GUI9_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490128}; Flags: Fragment;+++[A0A1B0GUV4_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490259};+++[A0A1B0GVS0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490629}; Flags: Fragment;+++[A0A1B0GVS6_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000490637};+++[B7Z4H4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ61315, highly similar to Membrane-associated guanylate kinase, WW andPDZ domain-containing protein 2 {ECO:0000313|EMBL:BAH12560.1};+++[D6W5N0_HUMAN|Unreviewed]SubName: Full=Membrane associated guanylate kinase, WW and PDZ domain containing 2, isoform CRA_b {ECO:0000313|EMBL:EAW77023.1};+++[E7EWI0_HUMAN|Unreviewed]SubName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 {ECO:0000313|Ensembl:ENSP00000428389};"]
[9865,"'TRIL'",5,5,5,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0031012///extracellular matrix+++GO:0005615///extracellular space+++GO:0046696///lipopolysaccharide receptor complex","GO:0001530///lipopolysaccharide binding","GO:0002376///immune system process+++GO:0006954///inflammatory response+++GO:0034142///toll-like receptor 4 signaling pathway+++GO:0045087///innate immune response+++GO:0002718///regulation of cytokine production involved in immune response","IPR001611///Leucine-rich repeat+++IPR032675///Leucine-rich repeat domain superfamily+++IPR003961///Fibronectin type III+++IPR000483///Cysteine-rich flanking region, C-terminal+++IPR003591///Leucine-rich repeat, typical subtype","[TRIL_HUMAN|Reviewed]RecName: Full=TLR4 interactor with leucine rich repeats; AltName: Full=Leucine-rich repeat-containing protein KIAA0644; Flags: Precursor;"]
[9866,"'TRIM66'",176.99,263,219.995,{"$nulls":4},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0016235///aggresome","GO:0003682///chromatin binding+++GO:0046872///metal ion binding+++GO:0008270///zinc ion binding","GO:0045892///negative regulation of transcription, DNA-templated","IPR019786///Zinc finger, PHD-type, conserved site+++IPR037372///Tripartite motif-containing protein 66+++IPR003649///B-box, C-terminal+++IPR036427///Bromodomain-like superfamily+++IPR019787///Zinc finger, PHD-finger+++IPR001487///Bromodomain+++IPR001965///Zinc finger, PHD-type+++IPR011011///Zinc finger, FYVE/PHD-type+++IPR000315///B-box-type zinc finger","[TRI66_HUMAN|Reviewed]RecName: Full=Tripartite motif-containing protein 66;+++[A0A2R8YE93_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000494157}; Flags: Fragment;+++[A0A2R8YEA1_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000495413};+++[B5MCJ9_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000384876};+++[H0YF52_HUMAN|Unreviewed]SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|Ensembl:ENSP00000437234}; Flags: Fragment;"]
[9867,"'PJA2'",1035,1348,1191.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0045202///synapse+++GO:0005783///endoplasmic reticulum+++GO:0045211///postsynaptic membrane+++GO:0000139///Golgi membrane+++GO:0014069///postsynaptic density+++GO:0005886///plasma membrane+++GO:0030054///cell junction+++GO:0045111///intermediate filament cytoskeleton+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005789///endoplasmic reticulum membrane+++GO:0005737///cytoplasm","GO:0034236///protein kinase A catalytic subunit binding+++GO:0046872///metal ion binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0034237///protein kinase A regulatory subunit binding+++GO:0005515///protein binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity","GO:0006954///inflammatory response+++GO:0035329///hippo signaling+++GO:0016567///protein ubiquitination+++GO:1900745///positive regulation of p38MAPK cascade+++GO:0046330///positive regulation of JNK cascade+++GO:0045087///innate immune response+++GO:0043030///regulation of macrophage activation+++GO:0034137///positive regulation of toll-like receptor 2 signaling pathway+++GO:0010738///regulation of protein kinase A signaling+++GO:0007616///long-term memory","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR030639///E3 ubiquitin-protein ligase Praja-2+++IPR001841///Zinc finger, RING-type","[PJA2_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase Praja-2; Short=Praja2; EC=2.3.2.27; AltName: Full=RING finger protein 131; AltName: Full=RING-type E3 ubiquitin transferase Praja-2 {ECO:0000305};"]
[9868,"'TOMM70'",646,633,639.5,{"$nulls":4},"GO:0005742///mitochondrial outer membrane translocase complex+++GO:0070062///extracellular exosome+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane","GO:0008320///protein transmembrane transporter activity+++GO:0005515///protein binding","GO:0071806///protein transmembrane transport+++GO:0006626///protein targeting to mitochondrion","IPR001440///Tetratricopeptide repeat 1+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR019734///Tetratricopeptide repeat","[TOM70_HUMAN|Reviewed]RecName: Full=Mitochondrial import receptor subunit TOM70; AltName: Full=Mitochondrial precursor proteins import receptor; AltName: Full=Translocase of outer membrane 70 kDa subunit; AltName: Full=Translocase of outer mitochondrial membrane protein 70 {ECO:0000312|HGNC:HGNC:11985};"]
[9869,"'SETDB1'",343,350,346.5,"04550///Signaling pathways regulating pluripotency of stem cells+++00310///Lysine degradation",null,null,"R04867///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6,N6-dimethyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6,N6-trimethyl-L-lysine+++R04866///S-adenosyl-L-methionine:cytochrome-c-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Protein N6-methyl-L-lysine <=> S-Adenosyl-L-homocysteine + Protein N6,N6-dimethyl-L-lysine+++R03938///S-Adenosyl-L-methionine:histone-L-lysine N6-methyltransferase   S-Adenosyl-L-methionine + Histone-L-lysine <=> S-Adenosyl-L-homocysteine + Histone N6-methyl-L-lysine+++R03875///Protein lysine + S-Adenosyl-L-methionine <=> Protein N6-methyl-L-lysine + S-Adenosyl-L-homocysteine","GO:0005694///chromosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005886///plasma membrane+++GO:0005654///nucleoplasm","GO:0018024///histone-lysine N-methyltransferase activity+++GO:0003682///chromatin binding+++GO:0008168///methyltransferase activity+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:1990841///promoter-specific chromatin binding+++GO:0016740///transferase activity","GO:0045471///response to ethanol+++GO:0032259///methylation+++GO:0090309///positive regulation of methylation-dependent chromatin silencing+++GO:0006325///chromatin organization+++GO:0033273///response to vitamin+++GO:0007265///Ras protein signal transduction+++GO:0034968///histone lysine methylation","IPR007728///Pre-SET domain+++IPR002999///Tudor domain+++IPR003616///Post-SET domain+++IPR016177///DNA-binding domain superfamily+++IPR001739///Methyl-CpG DNA binding+++IPR001214///SET domain+++IPR025796///Histone-lysine N-methyltransferase SETDB1","[SETB1_HUMAN|Reviewed]RecName: Full=Histone-lysine N-methyltransferase SETDB1; EC=2.1.1.43; AltName: Full=ERG-associated protein with SET domain; Short=ESET; AltName: Full=Histone H3-K9 methyltransferase 4; Short=H3-K9-HMTase 4; AltName: Full=Lysine N-methyltransferase 1E; AltName: Full=SET domain bifurcated 1;+++[B0QZE6_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000409379}; Flags: Fragment;+++[E9PAP1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357960};+++[E9PQM8_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000436148}; Flags: Fragment;+++[E9PRF4_HUMAN|Unreviewed]RecName: Full=Histone-lysine N-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00906}; EC=2.1.1.43 {ECO:0000256|PROSITE-ProRule:PRU00906}; Flags: Fragment;+++[E9PS59_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000435922}; Flags: Fragment;+++[X6R732_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000357959};+++[X6RHV1_HUMAN|Unreviewed]SubName: Full=Histone-lysine N-methyltransferase SETDB1 {ECO:0000313|Ensembl:ENSP00000407831}; Flags: Fragment;"]
[987,"'LRBA'",391,648,519.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005783///endoplasmic reticulum+++GO:0005886///plasma membrane+++GO:0005764///lysosome+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0008150///biological_process","IPR016024///Armadillo-type fold+++IPR036322///WD40-repeat-containing domain superfamily+++IPR036372///BEACH domain superfamily+++IPR023362///PH-BEACH domain+++IPR031570///Domain of unknown function DUF4704+++IPR001680///WD40 repeat+++IPR011989///Armadillo-like helical+++IPR010508///Domain of unknown function DUF1088+++IPR000409///BEACH domain+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR013320///Concanavalin A-like lectin/glucanase domain superfamily","[LRBA_HUMAN|Reviewed]RecName: Full=Lipopolysaccharide-responsive and beige-like anchor protein; AltName: Full=Beige-like protein; AltName: Full=CDC4-like protein;+++[E9PEM5_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000422180};+++[H0Y9N9_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000424640}; Flags: Fragment;+++[H0YA17_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000425852}; Flags: Fragment;+++[H0YAC6_HUMAN|Unreviewed]SubName: Full=Lipopolysaccharide-responsive and beige-like anchor protein {ECO:0000313|Ensembl:ENSP00000426669}; Flags: Fragment;+++[Q6P1X2_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH64834.1};+++[Q969R7_HUMAN|Unreviewed]SubName: Full=LRBA protein {ECO:0000313|EMBL:AAH12535.2}; Flags: Fragment;"]
[9870,"'AREL1'",632,953,792.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005737///cytoplasm","GO:0061630///ubiquitin protein ligase activity+++GO:0016740///transferase activity+++GO:0004842///ubiquitin-protein transferase activity","GO:0000209///protein polyubiquitination+++GO:0016567///protein ubiquitination+++GO:0043066///negative regulation of apoptotic process+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0045732///positive regulation of protein catabolic process+++GO:0006915///apoptotic process+++GO:0006511///ubiquitin-dependent protein catabolic process","IPR000569///HECT domain+++IPR000408///Regulator of chromosome condensation, RCC1+++IPR013783///Immunoglobulin-like fold+++IPR014756///Immunoglobulin E-set+++IPR035983///HECT, E3 ligase catalytic domain+++IPR017868///Filamin/ABP280 repeat-like","[AREL1_HUMAN|Reviewed]RecName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1; EC=2.3.2.26; AltName: Full=Apoptosis-resistant HECT-type E3 ubiquitin transferase 1;+++[G3V245_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450458}; Flags: Fragment;+++[G3V2B5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450557};+++[G3V506_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452101}; Flags: Fragment;+++[G3V5P7_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000452456};+++[H0YJ67_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450901}; Flags: Fragment;+++[H0YJ69_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000450912}; Flags: Fragment;+++[H0YJF1_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451375}; Flags: Fragment;+++[H0YJK5_HUMAN|Unreviewed]SubName: Full=Apoptosis-resistant E3 ubiquitin protein ligase 1 {ECO:0000313|Ensembl:ENSP00000451710}; Flags: Fragment;+++[L8E7E7_HUMAN|Unreviewed]SubName: Full=Alternative protein KIAA0317 {ECO:0000313|EMBL:CCQ43054.1};"]
[9871,"'SEC24D'",1114,1912,1513,"04141///Protein processing in endoplasmic reticulum","H01572///Cole-Carpenter syndrome","M00404///COPII complex",null,"GO:0005789///endoplasmic reticulum membrane+++GO:0005829///cytosol+++GO:0030127///COPII vesicle coat+++GO:0012507///ER to Golgi transport vesicle membrane+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0000139///Golgi membrane+++GO:0031410///cytoplasmic vesicle+++GO:0005783///endoplasmic reticulum","GO:0000149///SNARE binding+++GO:0008270///zinc ion binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding","GO:0090110///cargo loading into COPII-coated vesicle+++GO:0019886///antigen processing and presentation of exogenous peptide antigen via MHC class II+++GO:0016192///vesicle-mediated transport+++GO:0001701///in utero embryonic development+++GO:0006888///ER to Golgi vesicle-mediated transport+++GO:0006886///intracellular protein transport+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0002474///antigen processing and presentation of peptide antigen via MHC class I","IPR007123///Gelsolin-like domain+++IPR036175///Sec23/Sec24 helical domain superfamily+++IPR012990///Sec23/Sec24 beta-sandwich+++IPR006900///Sec23/Sec24, helical domain+++IPR006895///Zinc finger, Sec23/Sec24-type+++IPR036465///von Willebrand factor A-like domain superfamily+++IPR036180///Gelsolin-like domain superfamily+++IPR029006///ADF-H/Gelsolin-like domain superfamily+++IPR006896///Sec23/Sec24, trunk domain","[SC24D_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec24D {ECO:0000305}; AltName: Full=SEC24-related protein D;+++[A8K6V0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ78676, highly similar to Homo sapiens SEC24 related gene family, member D (SEC24D), mRNA {ECO:0000313|EMBL:BAF84454.1};+++[D6RAE2_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000422717};+++[D6RBM1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000424085};+++[D6RGJ5_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000426309}; Flags: Fragment;+++[E9PC44_HUMAN|Unreviewed]SubName: Full=cDNA FLJ43974 fis, clone TESTI4018101, highly similar to Protein transport protein Sec24D {ECO:0000313|EMBL:BAG54271.1};+++[E9PDM8_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000425491};+++[E9PG84_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec24D {ECO:0000313|Ensembl:ENSP00000427249};+++[Q49AI3_HUMAN|Unreviewed]SubName: Full=SEC24D protein {ECO:0000313|EMBL:AAH37736.1};+++[Q4W5D3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein SEC24D {ECO:0000313|EMBL:AAY40935.1}; Flags: Fragment;"]
[9873,"'FCHSD2'",190,208,199,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0055037///recycling endosome","GO:0005515///protein binding","GO:0007274///neuromuscular synaptic transmission+++GO:0030833///regulation of actin filament polymerization","IPR031160///F-BAR domain+++IPR035556///FCHSD2, SH3 domain 2+++IPR001060///FCH domain+++IPR027267///AH/BAR domain superfamily+++IPR034936///F-BAR and double SH3 domains protein+++IPR001452///SH3 domain+++IPR036028///SH3-like domain superfamily+++IPR034934///F-BAR and double SH3 domains protein 2+++IPR035460///FCHSD, SH3 domain 1","[FCSD2_HUMAN|Reviewed]RecName: Full=F-BAR and double SH3 domains protein 2; AltName: Full=Carom; AltName: Full=SH3 multiple domains protein 3;+++[A0A024R5H2_HUMAN|Unreviewed]SubName: Full=FCH and double SH3 domains 2, isoform CRA_a {ECO:0000313|EMBL:EAW74881.1};+++[B8ZZW8_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386903};+++[C9JM66_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000408706}; Flags: Fragment;+++[E7ENZ2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000402972};+++[E9PG19_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000386987};+++[H0Y6M2_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000406420}; Flags: Fragment;+++[H0YG35_HUMAN|Unreviewed]SubName: Full=F-BAR and double SH3 domains protein 2 {ECO:0000313|Ensembl:ENSP00000441616}; Flags: Fragment;"]
[9874,"'TLK1'",454,570,512,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus","GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0004674///protein serine/threonine kinase activity","GO:0006468///protein phosphorylation+++GO:0006974///cellular response to DNA damage stimulus+++GO:0016310///phosphorylation+++GO:0035556///intracellular signal transduction+++GO:0006325///chromatin organization+++GO:0001672///regulation of chromatin assembly or disassembly+++GO:0007049///cell cycle+++GO:0006886///intracellular protein transport","IPR000719///Protein kinase domain+++IPR008271///Serine/threonine-protein kinase, active site+++IPR017441///Protein kinase, ATP binding site+++IPR011009///Protein kinase-like domain superfamily","[TLK1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase tousled-like 1; EC=2.7.11.1; AltName: Full=PKU-beta; AltName: Full=Tousled-like kinase 1;+++[B3KRP1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000387313}; SubName: Full=Tousled-like kinase 1, isoform CRA_b {ECO:0000313|EMBL:EAX11221.1}; SubName: Full=cDNA FLJ34656 fis, clone KIDNE2018352, highly similar to Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|EMBL:BAG52453.1};+++[C9JWT6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000393165}; Flags: Fragment;+++[F8W7X8_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase tousled-like 1 {ECO:0000313|Ensembl:ENSP00000352810};+++[Q53TE4_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAY15077.1}; Flags: Fragment;+++[Q53TF9_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein TLK1 {ECO:0000313|EMBL:AAX93162.1}; Flags: Fragment;"]
[9875,"'URB1'",682,973,827.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0001650///fibrillar center+++GO:0005730///nucleolus","GO:0003723///RNA binding","GO:0008150///biological_process+++GO:0000463///maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)+++GO:0000466///maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","IPR039844///Nucleolar pre-ribosomal-associated protein 1+++IPR016024///Armadillo-type fold+++IPR021714///Nucleolar pre-ribosomal-associated protein 1, N-terminal+++IPR032436///Nucleolar pre-ribosomal-associated protein 1, C-terminal domain","[NPA1P_HUMAN|Reviewed]RecName: Full=Nucleolar pre-ribosomal-associated protein 1; AltName: Full=Nucleolar protein 254 kDa; AltName: Full=URB1 ribosome biogenesis 1 homolog;"]
[9877,"'ZC3H11A'",1266.39,1608.81,1437.6,{"$nulls":4},"GO:0000346///transcription export complex+++GO:0005654///nucleoplasm","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003729///mRNA binding","GO:0006405///RNA export from nucleus+++GO:0016973///poly(A)+ mRNA export from nucleus+++GO:0006406///mRNA export from nucleus+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0031124///mRNA 3'-end processing+++GO:0051028///mRNA transport","IPR000571///Zinc finger, CCCH-type","[ZC11A_HUMAN|Reviewed]RecName: Full=Zinc finger CCCH domain-containing protein 11A;+++[A0A1W2PPR9_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000491483};+++[C9J0L0_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000406531}; Flags: Fragment;+++[E9PBY7_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000415072}; Flags: Fragment;+++[E9PQ61_HUMAN|Unreviewed]SubName: Full=Zinc finger CCCH domain-containing protein 11A {ECO:0000313|Ensembl:ENSP00000432602};+++[Q0D2N5_HUMAN|Unreviewed]SubName: Full=ZC3H11A protein {ECO:0000313|EMBL:AAH46137.1};"]
[9878,"'TOX4'",1624.01,1790,1707.005,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0030175///filopodium+++GO:0031225///anchored component of membrane+++GO:0072357///PTW/PP1 phosphatase complex+++GO:0005576///extracellular region+++GO:0042995///cell projection+++GO:0032432///actin filament bundle+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0042627///chylomicron+++GO:0001891///phagocytic cup+++GO:0030054///cell junction+++GO:0048471///perinuclear region of cytoplasm+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0032587///ruffle membrane+++GO:0002102///podosome+++GO:0005829///cytosol+++GO:0009986///cell surface+++GO:0016020///membrane+++GO:0070062///extracellular exosome+++GO:0005886///plasma membrane+++GO:0005615///extracellular space+++GO:0015629///actin cytoskeleton+++GO:0000785///chromatin+++GO:0034361///very-low-density lipoprotein particle+++GO:0005925///focal adhesion+++GO:0001725///stress fiber+++GO:0001726///ruffle","GO:0008201///heparin binding+++GO:0004806///triglyceride lipase activity+++GO:0052689///carboxylic ester hydrolase activity+++GO:0003779///actin binding+++GO:0051020///GTPase binding+++GO:0004465///lipoprotein lipase activity+++GO:0042802///identical protein binding+++GO:0016787///hydrolase activity+++GO:0034185///apolipoprotein binding+++GO:0051015///actin filament binding+++GO:0005102///signaling receptor binding+++GO:0003677///DNA binding+++GO:0004620///phospholipase activity+++GO:0017129///triglyceride binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0005178///integrin binding+++GO:0005509///calcium ion binding","GO:0051639///actin filament network formation+++GO:0050729///positive regulation of inflammatory response+++GO:0022617///extracellular matrix disassembly+++GO:0019433///triglyceride catabolic process+++GO:0031100///animal organ regeneration+++GO:0006641///triglyceride metabolic process+++GO:0034372///very-low-density lipoprotein particle remodeling+++GO:0010744///positive regulation of macrophage derived foam cell differentiation+++GO:0044319///wound healing, spreading of cells+++GO:0006644///phospholipid metabolic process+++GO:0019432///triglyceride biosynthetic process+++GO:0070328///triglyceride homeostasis+++GO:0016477///cell migration+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0002286///T cell activation involved in immune response+++GO:0009409///response to cold+++GO:0051004///regulation of lipoprotein lipase activity+++GO:0010737///protein kinase A signaling+++GO:0071803///positive regulation of podosome assembly+++GO:0034371///chylomicron remodeling+++GO:0006633///fatty acid biosynthetic process+++GO:0033157///regulation of intracellular protein transport+++GO:0016042///lipid catabolic process+++GO:0055096///low-density lipoprotein particle mediated signaling+++GO:0010890///positive regulation of sequestering of triglyceride+++GO:0090197///positive regulation of chemokine secretion+++GO:0042632///cholesterol homeostasis+++GO:0006629///lipid metabolic process+++GO:0009617///response to bacterium+++GO:0042493///response to drug+++GO:0009749///response to glucose+++GO:0010886///positive regulation of cholesterol storage+++GO:0051017///actin filament bundle assembly+++GO:0006357///regulation of transcription by RNA polymerase II","IPR037985///TOX high mobility group box family member 4+++IPR009071///High mobility group box domain+++IPR036910///High mobility group box domain superfamily","[TOX4_HUMAN|Reviewed]RecName: Full=TOX high mobility group box family member 4; AltName: Full=Epidermal Langerhans cell protein LCP1;+++[C9J919_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000406196}; Flags: Fragment;+++[C9JNL1_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000402195}; Flags: Fragment;+++[F8WBE8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000389333};+++[F8WC04_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392234};+++[F8WCL8_HUMAN|Unreviewed]SubName: Full=TOX high mobility group box family member 4 {ECO:0000313|Ensembl:ENSP00000392482};+++[Q5TBN3_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000408052}; Flags: Fragment;+++[Q5TBN5_HUMAN|Unreviewed]SubName: Full=Plastin-2 {ECO:0000313|Ensembl:ENSP00000402157}; Flags: Fragment;"]
[9879,"'DDX46'",459,450,454.5,"03040///Spliceosome",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0016020///membrane+++GO:0005634///nucleus+++GO:0015030///Cajal body","GO:0000166///nucleotide binding+++GO:0003723///RNA binding+++GO:0004386///helicase activity+++GO:0003676///nucleic acid binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity","GO:0008380///RNA splicing+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006397///mRNA processing","IPR001650///Helicase, C-terminal+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR014001///Helicase superfamily 1/2, ATP-binding domain+++IPR000629///ATP-dependent RNA helicase DEAD-box, conserved site+++IPR011545///DEAD/DEAH box helicase domain+++IPR014014///RNA helicase, DEAD-box type, Q motif","[DDX46_HUMAN|Reviewed]RecName: Full=Probable ATP-dependent RNA helicase DDX46; EC=3.6.4.13; AltName: Full=DEAD box protein 46; AltName: Full=PRP5 homolog;+++[A0A0C4DG89_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000416534};+++[D3DQA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_a {ECO:0000313|EMBL:EAW62242.1};+++[D6RJA6_HUMAN|Unreviewed]SubName: Full=DEAD (Asp-Glu-Ala-Asp) box polypeptide 46, isoform CRA_b {ECO:0000313|EMBL:EAW62239.1}; SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000427290};+++[H0Y9U3_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000425073}; Flags: Fragment;+++[H0YAD5_HUMAN|Unreviewed]SubName: Full=Probable ATP-dependent RNA helicase DDX46 {ECO:0000313|Ensembl:ENSP00000426767}; Flags: Fragment;+++[Q0VGL8_HUMAN|Unreviewed]SubName: Full=DDX46 protein {ECO:0000313|EMBL:AAI05599.1}; Flags: Fragment;"]
[988,"'CDC5L'",510,515,512.5,"03040///Spliceosome",null,"M00355///Spliceosome, 35S U5-snRNP+++M00353///Spliceosome, Prp19/CDC5L complex",null,"GO:0016020///membrane+++GO:0000974///Prp19 complex+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005681///spliceosomal complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0005662///DNA replication factor A complex+++GO:0071007///U2-type catalytic step 2 spliceosome+++GO:0016607///nuclear speck+++GO:0032993///protein-DNA complex+++GO:0071013///catalytic step 2 spliceosome","GO:0001222///transcription corepressor binding+++GO:0008157///protein phosphatase 1 binding+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003723///RNA binding+++GO:0043522///leucine zipper domain binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0071987///WD40-repeat domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0000278///mitotic cell cycle+++GO:0000398///mRNA splicing, via spliceosome+++GO:0044344///cellular response to fibroblast growth factor stimulus+++GO:0008380///RNA splicing+++GO:0006974///cellular response to DNA damage stimulus+++GO:1904568///cellular response to wortmannin+++GO:0072422///signal transduction involved in DNA damage checkpoint+++GO:0007049///cell cycle+++GO:0071352///cellular response to interleukin-2+++GO:1990646///cellular response to prolactin+++GO:1990090///cellular response to nerve growth factor stimulus+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006281///DNA repair+++GO:0006397///mRNA processing","IPR021786///Pre-mRNA splicing factor component Cdc5p/Cef1+++IPR001005///SANT/Myb domain+++IPR017930///Myb domain+++IPR009057///Homeobox-like domain superfamily+++IPR015495///Myb-like transcription factor","[CDC5L_HUMAN|Reviewed]RecName: Full=Cell division cycle 5-like protein; Short=Cdc5-like protein; AltName: Full=Pombe cdc5-related protein;"]
[9880,"'ZBTB39'",103,111,107,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0046872///metal ion binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR013087///Zinc finger C2H2-type+++IPR036236///Zinc finger C2H2 superfamily","[ZBT39_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 39;"]
[9881,"'TRANK1'",102,125,113.5,{"$nulls":5},"GO:0005524///ATP binding",null,"IPR020683///Ankyrin repeat-containing domain+++IPR019734///Tetratricopeptide repeat+++IPR002110///Ankyrin repeat+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR036770///Ankyrin repeat-containing domain superfamily+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR039904///TPR and ankyrin repeat-containing protein 1","[TRNK1_HUMAN|Reviewed]RecName: Full=TPR and ankyrin repeat-containing protein 1; AltName: Full=Lupus brain antigen 1 homolog;+++[A0A096LPF5_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000485569}; Flags: Fragment;+++[A0A2R8Y7N6_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496256}; Flags: Fragment;+++[A0A2R8Y890_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496740}; Flags: Fragment;+++[A0A2R8Y8A3_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496771};+++[A0A2R8YEM9_HUMAN|Unreviewed]SubName: Full=TPR and ankyrin repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000494480};+++[L8EAQ6_HUMAN|Unreviewed]SubName: Full=Alternative protein TRANK1 {ECO:0000313|EMBL:CCQ43463.1};"]
[9882,"'TBC1D4'",90,150,120,"04931///Insulin resistance+++04919///Thyroid hormone signaling pathway",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0031982///vesicle+++GO:0005829///cytosol","GO:0005096///GTPase activator activity+++GO:0017137///Rab GTPase binding","GO:0016192///vesicle-mediated transport+++GO:0032869///cellular response to insulin stimulus+++GO:0090630///activation of GTPase activity+++GO:0006886///intracellular protein transport+++GO:0031339///negative regulation of vesicle fusion+++GO:0043547///positive regulation of GTPase activity","IPR035969///Rab-GTPase-TBC domain superfamily+++IPR000195///Rab-GTPase-TBC domain+++IPR006020///PTB/PI domain+++IPR021785///Domain of unknown function DUF3350+++IPR033564///TBC1 domain family member 4+++IPR011993///PH-like domain superfamily","[TBCD4_HUMAN|Reviewed]RecName: Full=TBC1 domain family member 4; AltName: Full=Akt substrate of 160 kDa; Short=AS160;+++[A0A024R637_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 4, isoform CRA_b {ECO:0000313|EMBL:EAW80538.1};+++[Q5JU47_HUMAN|Unreviewed]SubName: Full=TBC1 domain family member 4 {ECO:0000313|Ensembl:ENSP00000396932}; Flags: Fragment;"]
[9883,"'POM121'",2202.14,3197.32,2699.73,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0016021///integral component of membrane+++GO:0031965///nuclear membrane+++GO:0005635///nuclear envelope+++GO:0005654///nucleoplasm+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0032389///MutLalpha complex","GO:0008139///nuclear localization sequence binding+++GO:0016887///ATPase activity+++GO:0003697///single-stranded DNA binding+++GO:0003964///RNA-directed DNA polymerase activity+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0017056///structural constituent of nuclear pore+++GO:0046872///metal ion binding","GO:0006606///protein import into nucleus+++GO:0016446///somatic hypermutation of immunoglobulin genes+++GO:0032199///reverse transcription involved in RNA-mediated transposition+++GO:0016032///viral process+++GO:0006310///DNA recombination+++GO:0006298///mismatch repair+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0032197///transposition, RNA-mediated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006406///mRNA export from nucleus+++GO:0006405///RNA export from nucleus","IPR026054///Nuclear pore complex protein+++IPR026090///Nuclear pore protein POM121","[P121A_HUMAN|Reviewed]RecName: Full=Nuclear envelope pore membrane protein POM 121; AltName: Full=Nuclear envelope pore membrane protein POM 121A; AltName: Full=Nucleoporin Nup121; AltName: Full=Pore membrane protein of 121 kDa;"]
[9884,"'LRRC37A'",88.6,123.55,106.075,{"$nulls":4},"GO:0043209///myelin sheath+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0030496///midbody","GO:0044877///protein-containing complex binding+++GO:0016887///ATPase activity+++GO:0017075///syntaxin-1 binding+++GO:0042623///ATPase activity, coupled+++GO:0000149///SNARE binding+++GO:0005524///ATP binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding","GO:0006813///potassium ion transport+++GO:0035494///SNARE complex disassembly+++GO:0015031///protein transport","IPR032675///Leucine-rich repeat domain superfamily+++IPR015753///Leucine-rich repeat-containing protein 37+++IPR001611///Leucine-rich repeat+++IPR029423///LRRC37A/B like protein 1, C-terminal+++IPR003591///Leucine-rich repeat, typical subtype+++IPR032754///Leucine-rich repeat-containing protein 37, N-terminal","[L37A1_HUMAN|Reviewed]RecName: Full=Leucine-rich repeat-containing protein 37A; Flags: Precursor;"]
[9885,"'OSBPL2'",574.88,573,573.94,"05222///Small cell lung cancer+++04512///ECM-receptor interaction+++04151///PI3K-Akt signaling pathway+++01100///Metabolic pathways+++05200///Pathways in cancer+++05146///Amoebiasis+++05145///Toxoplasmosis+++05165///Human papillomavirus infection+++04510///Focal adhesion","H00586///Epidermolysis bullosa, junctional+++H00813///Laryngo onycho cutaneous syndrome",null,null,"GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005829///cytosol","GO:0015248///sterol transporter activity+++GO:0005515///protein binding+++GO:0032934///sterol binding+++GO:0008289///lipid binding+++GO:0015485///cholesterol binding","GO:0006869///lipid transport+++GO:0015918///sterol transport+++GO:0006699///bile acid biosynthetic process","IPR018494///Oxysterol-binding protein, conserved site+++IPR000648///Oxysterol-binding protein+++IPR037239///Oxysterol-binding protein superfamily","[OSBL2_HUMAN|Reviewed]RecName: Full=Oxysterol-binding protein-related protein 2; Short=ORP-2; Short=OSBP-related protein 2;+++[A0A087WTV1_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000478158}; Flags: Fragment;+++[A0A087WVV0_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000479702}; Flags: Fragment;+++[A0A2R8Y362_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;+++[A0A2R8Y429_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000493721};+++[A0A2R8Y5B9_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000494692};+++[A0A2R8Y5R1_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y690_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8Y703_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495611};+++[A0A2R8YD49_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YDU7_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YEX0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YFT0_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG53_HUMAN|Unreviewed]SubName: Full=Oxysterol-binding protein-related protein 2 {ECO:0000313|Ensembl:ENSP00000495661}; Flags: Fragment;+++[A0A2R8YG59_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[A0A2R8YG95_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[B4DKJ8_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[E7ET92_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};+++[H0Y7X4_HUMAN|Unreviewed]RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845}; Flags: Fragment;"]
[9886,"'RHOBTB1'",409,453,431,"04120///Ubiquitin mediated proteolysis","H01852///Postaxial polydactyly+++H00513///Transient neonatal diabetes mellitus (TNDM)+++H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0005856///cytoskeleton","GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0019901///protein kinase binding+++GO:0000166///nucleotide binding","GO:0007015///actin filament organization+++GO:0030036///actin cytoskeleton organization+++GO:0007266///Rho protein signal transduction+++GO:0030838///positive regulation of actin filament polymerization+++GO:0031532///actin cytoskeleton reorganization+++GO:0043652///engulfment of apoptotic cell+++GO:0016477///cell migration+++GO:0007264///small GTPase mediated signal transduction+++GO:0000902///cell morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction","IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR003578///Small GTPase Rho+++IPR001806///Small GTPase","[RHBT1_HUMAN|Reviewed]RecName: Full=Rho-related BTB domain-containing protein 1;+++[A0A024QZL4_HUMAN|Unreviewed]SubName: Full=Rho-related BTB domain containing 1, isoform CRA_c {ECO:0000313|EMBL:EAW54216.1};+++[Q567T3_HUMAN|Unreviewed]SubName: Full=RHOBTB1 protein {ECO:0000313|EMBL:AAH93035.1};"]
[9887,"'SMG7'",1034,1543,1288.5,"03015///mRNA surveillance pathway",{"$nulls":3},"GO:0005634///nucleus+++GO:0005697///telomerase holoenzyme complex+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0045111///intermediate filament cytoskeleton","GO:0005515///protein binding+++GO:0042162///telomeric DNA binding+++GO:0004540///ribonuclease activity+++GO:0070034///telomerase RNA binding+++GO:0043021///ribonucleoprotein complex binding+++GO:0051721///protein phosphatase 2A binding","GO:0007004///telomere maintenance via telomerase+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0090501///RNA phosphodiester bond hydrolysis+++GO:0035303///regulation of dephosphorylation+++GO:0043487///regulation of RNA stability+++GO:0006406///mRNA export from nucleus","IPR019458///Telomerase activating protein Est1+++IPR018834///DNA/RNA-binding domain, Est1-type+++IPR011990///Tetratricopeptide-like helical domain superfamily","[SMG7_HUMAN|Reviewed]RecName: Full=Protein SMG7; AltName: Full=EST1-like protein C; AltName: Full=SMG-7 homolog; Short=hSMG-7;+++[B1ALB4_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000388390}; Flags: Fragment;+++[D6R9J3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422056}; Flags: Fragment;+++[D6RAD0_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000422742}; Flags: Fragment;+++[E9PBK2_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000400220};+++[E9PD50_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000356507};+++[E9PEK3_HUMAN|Unreviewed]SubName: Full=Protein SMG7 {ECO:0000313|Ensembl:ENSP00000410254};+++[Q6TV06_HUMAN|Unreviewed]SubName: Full=Breast cancer-associated antigen SGA-56M {ECO:0000313|EMBL:AAR25620.1}; SubName: Full=Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), isoform CRA_a {ECO:0000313|EMBL:EAW91154.1};"]
[9889,"'ZBED4'",416,498,457,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005737///cytoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0046983///protein dimerization activity+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0006357///regulation of transcription by RNA polymerase II","IPR037220///Zinc finger BED domain+++IPR036236///Zinc finger C2H2 superfamily+++IPR008906///HAT, C-terminal dimerisation domain+++IPR003656///Zinc finger, BED-type+++IPR012337///Ribonuclease H-like superfamily","[ZBED4_HUMAN|Reviewed]RecName: Full=Zinc finger BED domain-containing protein 4;"]
[989,"'SEPT7'",1068,1157,1112.5,{"$nulls":4},"GO:0070062///extracellular exosome+++GO:0016324///apical plasma membrane+++GO:0000775///chromosome, centromeric region+++GO:0005940///septin ring+++GO:0015630///microtubule cytoskeleton+++GO:0005737///cytoplasm+++GO:0042995///cell projection+++GO:0000777///condensed chromosome kinetochore+++GO:0005694///chromosome+++GO:0005819///spindle+++GO:0031105///septin complex+++GO:0005829///cytosol+++GO:0030496///midbody+++GO:0097730///non-motile cilium+++GO:0005634///nucleus+++GO:0031514///motile cilium+++GO:0005930///axoneme+++GO:0032160///septin filament array+++GO:0097227///sperm annulus+++GO:0032154///cleavage furrow+++GO:0001725///stress fiber+++GO:0005929///cilium+++GO:0000776///kinetochore+++GO:0005856///cytoskeleton","GO:0005515///protein binding+++GO:0032947///protein-containing complex scaffold activity+++GO:0005198///structural molecule activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding+++GO:0003924///GTPase activity+++GO:0042802///identical protein binding+++GO:0045296///cadherin binding","GO:0051301///cell division+++GO:0016476///regulation of embryonic cell shape+++GO:0000281///mitotic cytokinesis+++GO:0051291///protein heterooligomerization+++GO:0007049///cell cycle+++GO:0007283///spermatogenesis+++GO:0060271///cilium assembly+++GO:0030154///cell differentiation+++GO:1902857///positive regulation of non-motile cilium assembly+++GO:0000921///septin ring assembly","IPR008115///Septin 7+++IPR030379///Septin-type guanine nucleotide-binding (G) domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR016491///Septin","[SEPT7_HUMAN|Reviewed]RecName: Full=Septin-7; AltName: Full=CDC10 protein homolog;+++[A0A023T695_HUMAN|Unreviewed]SubName: Full=Septin 7 variant 4 {ECO:0000313|EMBL:AHX84171.1};+++[A0A024RA87_HUMAN|Unreviewed]SubName: Full=Septin 7, isoform CRA_a {ECO:0000313|EMBL:EAW94060.1};+++[A0A0U1RQW0_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489192}; Flags: Fragment;+++[A0A0U1RRD1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489466}; Flags: Fragment;+++[A0A0U1RRE1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489480}; Flags: Fragment;+++[A0A0U1RRH9_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489538}; Flags: Fragment;+++[A0A0U1RRM2_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000489596}; Flags: Fragment;+++[A8K3D0_HUMAN|Unreviewed]SubName: Full=cDNA FLJ75185 {ECO:0000313|EMBL:BAF83234.1};+++[B4DNE4_HUMAN|Unreviewed]SubName: Full=cDNA FLJ52574, highly similar to Septin-7 {ECO:0000313|EMBL:BAG60206.1};+++[E7EPK1_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000344868};+++[E7ES33_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000381993};+++[G3V1Q4_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000413507};+++[Q3B7A3_HUMAN|Unreviewed]SubName: Full=SEPT7 protein {ECO:0000313|EMBL:AAI07719.1}; Flags: Fragment;+++[Q5JXL7_HUMAN|Unreviewed]SubName: Full=Septin-7 {ECO:0000313|Ensembl:ENSP00000444240};+++[Q8TC62_HUMAN|Unreviewed]SubName: Full=Septin 7 {ECO:0000313|EMBL:AAH25987.3};"]
[9890,"'PLPPR4'",1,0,0.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0099061///integral component of postsynaptic density membrane+++GO:0005886///plasma membrane+++GO:0098978///glutamatergic synapse+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0005887///integral component of plasma membrane","GO:0016791///phosphatase activity+++GO:0016787///hydrolase activity+++GO:0008195///phosphatidate phosphatase activity+++GO:0042577///lipid phosphatase activity","GO:0007409///axonogenesis+++GO:0046839///phospholipid dephosphorylation+++GO:0043066///negative regulation of apoptotic process+++GO:0048839///inner ear development+++GO:0006644///phospholipid metabolic process","IPR028684///Phospholipid phosphatase-related protein type 4+++IPR000326///Phosphatidic acid phosphatase type 2/haloperoxidase+++IPR036938///Phosphatidic acid phosphatase type 2/haloperoxidase superfamily","[PLPR4_HUMAN|Reviewed]RecName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000305}; EC=3.1.3.4; AltName: Full=Brain-specific phosphatidic acid phosphatase-like protein 1 {ECO:0000303|Ref.7}; AltName: Full=Lipid phosphate phosphatase-related protein type 4 {ECO:0000303|Ref.2}; AltName: Full=Plasticity-related gene 1 protein {ECO:0000305|PubMed:12730698}; Short=PRG-1 {ECO:0000303|PubMed:12730698};+++[Q3ZCT6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH41386.1}; Flags: Fragment;+++[Q86XM6_HUMAN|Unreviewed]SubName: Full=LPPR4 protein {ECO:0000313|EMBL:AAH42963.1}; Flags: Fragment;+++[W4VSQ3_HUMAN|Unreviewed]SubName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000313|Ensembl:ENSP00000359203};"]
[9891,"'NUAK1'",847,1105,976,{"$nulls":4},"GO:0001650///fibrillar center+++GO:0015630///microtubule cytoskeleton+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0000166///nucleotide binding+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0016740///transferase activity+++GO:0002039///p53 binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0042127///regulation of cell proliferation+++GO:1901796///regulation of signal transduction by p53 class mediator+++GO:0007155///cell adhesion+++GO:0030155///regulation of cell adhesion+++GO:0035556///intracellular signal transduction+++GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation+++GO:0035507///regulation of myosin-light-chain-phosphatase activity+++GO:0006974///cellular response to DNA damage stimulus+++GO:2000772///regulation of cellular senescence","IPR017441///Protein kinase, ATP binding site+++IPR008271///Serine/threonine-protein kinase, active site+++IPR000719///Protein kinase domain+++IPR011009///Protein kinase-like domain superfamily","[NUAK1_HUMAN|Reviewed]RecName: Full=NUAK family SNF1-like kinase 1; EC=2.7.11.1; AltName: Full=AMPK-related protein kinase 5; Short=ARK5; AltName: Full=Omphalocele kinase 1;+++[A0A024RBL3_HUMAN|Unreviewed]SubName: Full=NUAK family, SNF1-like kinase, 1, isoform CRA_a {ECO:0000313|EMBL:EAW97769.1};+++[F8VSH4_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000448288}; Flags: Fragment;+++[F8VXF0_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000449990}; Flags: Fragment;+++[F8VZ96_HUMAN|Unreviewed]SubName: Full=NUAK family SNF1-like kinase 1 {ECO:0000313|Ensembl:ENSP00000446873}; Flags: Fragment;"]
[9892,"'SNAP91'",42,49,45.5,{"$nulls":4},"GO:0030136///clathrin-coated vesicle+++GO:0005886///plasma membrane+++GO:0016020///membrane+++GO:0005905///clathrin-coated pit","GO:0030276///clathrin binding+++GO:0005545///1-phosphatidylinositol binding+++GO:0005515///protein binding+++GO:0005543///phospholipid binding+++GO:0019901///protein kinase binding","GO:0048268///clathrin coat assembly+++GO:0015031///protein transport+++GO:2000369///regulation of clathrin-dependent endocytosis","IPR014712///Phosphoinositide-binding clathrin adaptor, domain 2+++IPR008942///ENTH/VHS+++IPR011417///AP180 N-terminal homology (ANTH) domain+++IPR013809///ENTH  domain","[AP180_HUMAN|Reviewed]RecName: Full=Clathrin coat assembly protein AP180; AltName: Full=91 kDa synaptosomal-associated protein; AltName: Full=Clathrin coat-associated protein AP180; AltName: Full=Phosphoprotein F1-20;+++[A0A0A0MRM7_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358705}; Flags: Fragment;+++[B7Z2N2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57108, highly similar to Clathrin coat assembly protein AP180 {ECO:0000313|EMBL:BAH11918.1};+++[E5RFC6_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000358704}; Flags: Fragment;+++[E5RFU0_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000427959}; Flags: Fragment;+++[E5RGP8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429950};+++[E5RGY9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430071}; Flags: Fragment;+++[E5RHK9_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429700};+++[E5RIJ5_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429429}; Flags: Fragment;+++[E5RJY3_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000431055}; Flags: Fragment;+++[E5RK51_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430441}; Flags: Fragment;+++[E5RK53_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000428127};+++[E9PDG8_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000429776};+++[H0UI15_HUMAN|Unreviewed]SubName: Full=Synaptosomal-associated protein, 91kDa homolog (Mouse), isoform CRA_a {ECO:0000313|EMBL:EAW48659.1};+++[H0YBT2_HUMAN|Unreviewed]SubName: Full=Clathrin coat assembly protein AP180 {ECO:0000313|Ensembl:ENSP00000430255}; Flags: Fragment;"]
[9894,"'TELO2'",464,332,398,"04150///mTOR signaling pathway+++03460///Fanconi anemia pathway","H01789///You-Hoover-Fong syndrome",null,null,"GO:0000784///nuclear chromosome, telomeric region+++GO:0034399///nuclear periphery+++GO:0005622///intracellular+++GO:0031932///TORC2 complex+++GO:0016607///nuclear speck+++GO:0016604///nuclear body+++GO:0005829///cytosol+++GO:0005694///chromosome+++GO:0000781///chromosome, telomeric region+++GO:0005737///cytoplasm+++GO:0031931///TORC1 complex+++GO:0005634///nucleus+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0070209///ASTRA complex","GO:0005515///protein binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity+++GO:0044877///protein-containing complex binding+++GO:0004713///protein tyrosine kinase activity+++GO:0032947///protein-containing complex scaffold activity+++GO:0016301///kinase activity+++GO:0019901///protein kinase binding+++GO:0042802///identical protein binding+++GO:0004712///protein serine/threonine/tyrosine kinase activity+++GO:0042162///telomeric DNA binding+++GO:0051879///Hsp90 protein binding+++GO:0000166///nucleotide binding+++GO:0004674///protein serine/threonine kinase activity","GO:1904263///positive regulation of TORC1 signaling+++GO:0000723///telomere maintenance+++GO:0032526///response to retinoic acid+++GO:1904515///positive regulation of TORC2 signaling+++GO:0006468///protein phosphorylation+++GO:0045721///negative regulation of gluconeogenesis+++GO:0032006///regulation of TOR signaling+++GO:0016310///phosphorylation+++GO:0043484///regulation of RNA splicing+++GO:0046777///protein autophosphorylation+++GO:0010033///response to organic substance+++GO:0010212///response to ionizing radiation+++GO:0018108///peptidyl-tyrosine phosphorylation+++GO:0050821///protein stabilization+++GO:0071902///positive regulation of protein serine/threonine kinase activity","IPR016024///Armadillo-type fold+++IPR038528///TEL2, conserved domain superfamily+++IPR019337///Telomere length regulation protein, conserved domain","[TELO2_HUMAN|Reviewed]RecName: Full=Telomere length regulation protein TEL2 homolog; AltName: Full=Protein clk-2 homolog; Short=hCLK2;+++[B4DXS2_HUMAN|Unreviewed]SubName: Full=cDNA FLJ58340 {ECO:0000313|EMBL:BAG63484.1};+++[H3BRS3_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000456383};+++[H3BU45_HUMAN|Unreviewed]SubName: Full=Telomere length regulation protein TEL2 homolog {ECO:0000313|Ensembl:ENSP00000457461}; Flags: Fragment;+++[Q9BRG8_HUMAN|Unreviewed]SubName: Full=CLK2 protein {ECO:0000313|EMBL:AAH06274.2}; Flags: Fragment;"]
[9895,"'TECPR2'",1114,1120,1117,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005829///cytosol","GO:0005515///protein binding","GO:0006914///autophagy","IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR029772///Tectonin beta-propeller repeat-containing protein 2+++IPR009091///Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II+++IPR001680///WD40 repeat+++IPR006624///Beta-propeller repeat TECPR","[TCPR2_HUMAN|Reviewed]RecName: Full=Tectonin beta-propeller repeat-containing protein 2; AltName: Full=WD repeat-containing protein KIAA0329/KIAA0297;+++[L8E8K7_HUMAN|Unreviewed]SubName: Full=Alternative protein TECPR2 {ECO:0000313|EMBL:CCQ43464.1};"]
[9896,"'FIG4'",368,339,353.5,"00240///Pyrimidine metabolism+++01100///Metabolic pathways+++00230///Purine metabolism+++01110///Biosynthesis of secondary metabolites+++01130///Biosynthesis of antibiotics+++04140///Autophagy - animal+++04137///Mitophagy - animal",null,"M00052///Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP+++M00049///Adenine ribonucleotide biosynthesis, IMP => ADP,ATP+++M00053///Pyrimidine deoxyribonuleotide biosynthesis, CDP/CTP => dCDP/dCTP,dTDP/dTTP","R02326///ATP:dCDP phosphotransferase ATP + dCDP <=> ADP + dCTP+++R00156///ATP:UDP phosphotransferase ATP + UDP <=> ADP + UTP+++R00722///ATP:IDP phosphotransferase ATP + IDP <=> ADP + ITP+++R02093///ATP:dTDP phosphotransferase ATP + dTDP <=> ADP + dTTP+++R01547///ATP:dAMP phosphotransferase ATP + dAMP <=> ADP + dADP+++R00330///ATP:GDP phosphotransferase ATP + GDP <=> ADP + GTP+++R00570///ATP:CDP phosphotransferase ATP + CDP <=> ADP + CTP+++R00124///ATP:ADP phosphatransferase ATP + ADP <=> ADP + ATP+++R03530///ATP:dIDP phosphotransferase ATP + dIDP <=> ADP + dITP+++R00127///ATP:AMP phosphotransferase ATP + AMP <=> 2 ADP+++R01857///ATP:dGDP phosphotransferase ATP + dGDP <=> ADP + dGTP+++R02331///ATP:dUDP phosphotransferase ATP + dUDP <=> ADP + dUTP+++R01137///ATP:dADP phosphotransferase ATP + dADP <=> ADP + dATP","GO:0043231///intracellular membrane-bounded organelle+++GO:0031901///early endosome membrane+++GO:0031902///late endosome membrane+++GO:0010008///endosome membrane+++GO:0005783///endoplasmic reticulum+++GO:0000139///Golgi membrane+++GO:0005811///lipid droplet+++GO:0055037///recycling endosome+++GO:0016020///membrane+++GO:0005768///endosome+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0042578///phosphoric ester hydrolase activity+++GO:0034593///phosphatidylinositol bisphosphate phosphatase activity+++GO:0004438///phosphatidylinositol-3-phosphatase activity+++GO:0043813///phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity+++GO:0005515///protein binding+++GO:0016787///hydrolase activity+++GO:0043812///phosphatidylinositol-4-phosphate phosphatase activity","GO:0046488///phosphatidylinositol metabolic process+++GO:0010976///positive regulation of neuron projection development+++GO:0007626///locomotory behavior+++GO:0032288///myelin assembly+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0048666///neuron development+++GO:0016311///dephosphorylation+++GO:0031642///negative regulation of myelination+++GO:0007033///vacuole organization+++GO:0043473///pigmentation+++GO:0036092///phosphatidylinositol-3-phosphate biosynthetic process","IPR002013///SAC domain","[FIG4_HUMAN|Reviewed]RecName: Full=Polyphosphoinositide phosphatase; EC=3.1.3.-; AltName: Full=Phosphatidylinositol 3,5-bisphosphate 5-phosphatase; AltName: Full=SAC domain-containing protein 3;+++[H0Y6G7_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000405660}; Flags: Fragment;+++[Q5JRV4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000396566}; Flags: Fragment;+++[Q5TCS4_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000357937};+++[Q5TCS5_HUMAN|Unreviewed]SubName: Full=Polyphosphoinositide phosphatase {ECO:0000313|Ensembl:ENSP00000412156}; Flags: Fragment;"]
[9897,"'WASHC5'",885,933,909,"04144///Endocytosis","H00266///Hereditary spastic paraplegia (SPG)+++H01568///3C syndrome",null,null,"GO:0005768///endosome+++GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0005769///early endosome+++GO:0071203///WASH complex+++GO:0043025///neuronal cell body+++GO:0043005///neuron projection+++GO:0005737///cytoplasm+++GO:0005783///endoplasmic reticulum","GO:0005515///protein binding","GO:0001556///oocyte maturation+++GO:0040038///polar body extrusion after meiotic divisions+++GO:0010976///positive regulation of neuron projection development+++GO:0090306///spindle assembly involved in meiosis+++GO:0015031///protein transport+++GO:0016197///endosomal transport","IPR019393///WASH complex, subunit strumpellin","[WASC5_HUMAN|Reviewed]RecName: Full=WASH complex subunit 5 {ECO:0000312|HGNC:HGNC:28984}; AltName: Full=Strumpellin; AltName: Full=WASH complex subunit strumpellin {ECO:0000305};+++[E5RFU6_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000427946}; Flags: Fragment;+++[E7EQI7_HUMAN|Unreviewed]SubName: Full=WASH complex subunit 5 {ECO:0000313|Ensembl:ENSP00000429676};"]
[9898,"'UBAP2L'",5381,5616,5498.5,null,"H00100///Neutropenic disorders",null,null,"GO:0031519///PcG protein complex+++GO:0005671///Ada2/Gcn5/Ada3 transcription activator complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0005515///protein binding+++GO:0003723///RNA binding","GO:0007339///binding of sperm to zona pellucida+++GO:0061484///hematopoietic stem cell homeostasis","IPR015940///Ubiquitin-associated domain+++IPR022166///Protein of unknown function DUF3697, ubiquitin-associated protein 2+++IPR009060///UBA-like superfamily","[UBP2L_HUMAN|Reviewed]RecName: Full=Ubiquitin-associated protein 2-like; AltName: Full=Protein NICE-4;+++[B4DYY5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55671, highly similar to Ubiquitin-associated protein 2-like {ECO:0000313|EMBL:BAG63897.1};+++[F8W726_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000271877};+++[H0Y5H6_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000398609}; Flags: Fragment;+++[H7C2T8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000407672}; Flags: Fragment;+++[Q5VU77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000357490}; Flags: Fragment;+++[Q5VU78_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389052}; Flags: Fragment;+++[Q5VU79_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000389717}; Flags: Fragment;+++[Q5VU80_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000415310}; Flags: Fragment;+++[Q5VU81_HUMAN|Unreviewed]SubName: Full=Ubiquitin-associated protein 2-like {ECO:0000313|Ensembl:ENSP00000399920}; Flags: Fragment;"]
[9899,"'SV2B'",6.02,7.01,6.515,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0030672///synaptic vesicle membrane+++GO:0005886///plasma membrane+++GO:0031410///cytoplasmic vesicle+++GO:0043005///neuron projection+++GO:0001669///acrosomal vesicle+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0045202///synapse+++GO:0008021///synaptic vesicle+++GO:0030054///cell junction","GO:0005515///protein binding+++GO:0005215///transporter activity+++GO:0022857///transmembrane transporter activity","GO:0007268///chemical synaptic transmission+++GO:0055085///transmembrane transport+++GO:0006836///neurotransmitter transport","IPR005828///Major facilitator,  sugar transporter-like+++IPR011701///Major facilitator superfamily+++IPR005829///Sugar transporter, conserved site+++IPR022308///Synaptic vesicle protein SV2+++IPR036259///MFS transporter superfamily+++IPR001646///Pentapeptide repeat+++IPR020846///Major facilitator superfamily domain","[SV2B_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2B;"]
[990,"'CDC6'",61,69,65,"04110///Cell cycle+++04111///Cell cycle - yeast+++04113///Meiosis - yeast","H01889///Meier-Gorlin syndrome",null,null,"GO:0005634///nucleus+++GO:0000922///spindle pole+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0051233///spindle midzone+++GO:0005730///nucleolus+++GO:0005654///nucleoplasm","GO:0005515///protein binding+++GO:0019900///kinase binding+++GO:0003688///DNA replication origin binding+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding","GO:0006270///DNA replication initiation+++GO:0048146///positive regulation of fibroblast proliferation+++GO:0008285///negative regulation of cell proliferation+++GO:0030071///regulation of mitotic metaphase/anaphase transition+++GO:0051984///positive regulation of chromosome segregation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:1904385///cellular response to angiotensin+++GO:0007049///cell cycle+++GO:0008156///negative regulation of DNA replication+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0032467///positive regulation of cytokinesis+++GO:0033314///mitotic DNA replication checkpoint+++GO:0000083///regulation of transcription involved in G1/S transition of mitotic cell cycle+++GO:0007089///traversing start control point of mitotic cell cycle+++GO:0000076///DNA replication checkpoint+++GO:1904117///cellular response to vasopressin+++GO:0006260///DNA replication+++GO:0051301///cell division+++GO:0045737///positive regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000278///mitotic cell cycle","IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR015163///Cdc6, C-terminal+++IPR016314///Cell division protein Cdc6/18+++IPR003593///AAA+ ATPase domain+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[CDC6_HUMAN|Reviewed]RecName: Full=Cell division control protein 6 homolog; AltName: Full=CDC6-related protein; AltName: Full=Cdc18-related protein; Short=HsCdc18; AltName: Full=p62(cdc6); Short=HsCDC6;+++[A0A024R1S2_HUMAN|Unreviewed]RecName: Full=Cell division control protein {ECO:0000256|PIRNR:PIRNR001767};+++[J3KTI7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463004}; Flags: Fragment;+++[J3QLN7_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000463635}; Flags: Fragment;+++[J3QR52_HUMAN|Unreviewed]SubName: Full=Cell division control protein 6 homolog {ECO:0000313|Ensembl:ENSP00000464047}; Flags: Fragment;"]
[9900,"'SV2A'",144,183,163.5,"04512///ECM-receptor interaction",{"$nulls":3},"GO:0031594///neuromuscular junction+++GO:0031410///cytoplasmic vesicle+++GO:0030054///cell junction+++GO:0016021///integral component of membrane+++GO:0048786///presynaptic active zone+++GO:0045202///synapse+++GO:0098982///GABA-ergic synapse+++GO:0005886///plasma membrane+++GO:0005911///cell-cell junction+++GO:0098978///glutamatergic synapse+++GO:0030285///integral component of synaptic vesicle membrane+++GO:0008021///synaptic vesicle+++GO:0016020///membrane+++GO:0030672///synaptic vesicle membrane+++GO:0043025///neuronal cell body+++GO:0005783///endoplasmic reticulum+++GO:0043005///neuron projection+++GO:0030425///dendrite","GO:0005215///transporter activity+++GO:0019901///protein kinase binding+++GO:0022857///transmembrane transporter activity","GO:0055085///transmembrane transport+++GO:0014052///regulation of gamma-aminobutyric acid secretion+++GO:0006874///cellular calcium ion homeostasis+++GO:0006836///neurotransmitter transport+++GO:0007268///chemical synaptic transmission+++GO:0016082///synaptic vesicle priming","IPR001646///Pentapeptide repeat+++IPR005828///Major facilitator,  sugar transporter-like+++IPR005829///Sugar transporter, conserved site+++IPR020846///Major facilitator superfamily domain+++IPR036259///MFS transporter superfamily+++IPR011701///Major facilitator superfamily+++IPR022308///Synaptic vesicle protein SV2","[SV2A_HUMAN|Reviewed]RecName: Full=Synaptic vesicle glycoprotein 2A;+++[B4E000_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57689, highly similar to Synaptic vesicle glycoprotein 2A {ECO:0000313|EMBL:BAG64262.1};+++[L8E840_HUMAN|Unreviewed]SubName: Full=Alternative protein SV2A {ECO:0000313|EMBL:CCQ43465.1};"]
[9901,"'SRGAP3'",147,232,189.5,"04360///Axon guidance",{"$nulls":3},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005730///nucleolus","GO:0003964///RNA-directed DNA polymerase activity+++GO:0046872///metal ion binding+++GO:0016423///tRNA (guanine) methyltransferase activity+++GO:0003723///RNA binding+++GO:0009036///type II site-specific deoxyribonuclease activity+++GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity","GO:0007165///signal transduction+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0032197///transposition, RNA-mediated+++GO:0030488///tRNA methylation+++GO:0006310///DNA recombination+++GO:0032199///reverse transcription involved in RNA-mediated transposition","IPR036028///SH3-like domain superfamily+++IPR035648///srGAP1/2/3, SH3 domain+++IPR001060///FCH domain+++IPR000198///Rho GTPase-activating protein domain+++IPR008936///Rho GTPase activation protein+++IPR001452///SH3 domain+++IPR031160///F-BAR domain+++IPR027267///AH/BAR domain superfamily","[SRGP3_HUMAN|Reviewed]RecName: Full=SLIT-ROBO Rho GTPase-activating protein 3; Short=srGAP3; AltName: Full=Mental disorder-associated GAP; AltName: Full=Rho GTPase-activating protein 14; AltName: Full=WAVE-associated Rac GTPase-activating protein; Short=WRP;"]
[9902,"'MRC2'",3465,5228,4346.5,"04145///Phagosome+++05152///Tuberculosis",{"$nulls":3},"GO:0005925///focal adhesion+++GO:0016020///membrane+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding+++GO:0004888///transmembrane signaling receptor activity+++GO:0005515///protein binding+++GO:0005518///collagen binding","GO:0030574///collagen catabolic process+++GO:0001649///osteoblast differentiation+++GO:0006897///endocytosis","IPR036943///Fibronectin type II domain superfamily+++IPR000772///Ricin B, lectin domain+++IPR035992///Ricin B-like lectins+++IPR016187///C-type lectin fold+++IPR016186///C-type lectin-like/link domain superfamily+++IPR001304///C-type lectin-like+++IPR000562///Fibronectin type II domain+++IPR013806///Kringle-like fold+++IPR018378///C-type lectin, conserved site+++IPR033989///CD209-like, C-type lectin-like domain","[MRC2_HUMAN|Reviewed]RecName: Full=C-type mannose receptor 2; AltName: Full=C-type lectin domain family 13 member E; AltName: Full=Endocytic receptor 180; AltName: Full=Macrophage mannose receptor 2; AltName: Full=Urokinase-type plasminogen activator receptor-associated protein; Short=UPAR-associated protein; Short=Urokinase receptor-associated protein; AltName: CD_antigen=CD280; Flags: Precursor;+++[E7EME3_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000400445};+++[J3KRF1_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000461968}; Flags: Fragment;+++[J3QQZ6_HUMAN|Unreviewed]SubName: Full=C-type mannose receptor 2 {ECO:0000313|Ensembl:ENSP00000463968}; Flags: Fragment;"]
[9903,"'KLHL21'",1735,1787,1761,{"$nulls":4},"GO:0005819///spindle+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0005827///polar microtubule","GO:0004842///ubiquitin-protein transferase activity","GO:0043687///post-translational protein modification+++GO:0007049///cell cycle+++GO:0051301///cell division+++GO:0035853///chromosome passenger complex localization to spindle midzone+++GO:0032465///regulation of cytokinesis+++GO:0016567///protein ubiquitination","IPR000210///BTB/POZ domain+++IPR015915///Kelch-type beta propeller+++IPR017096///BTB-kelch protein+++IPR011705///BTB/Kelch-associated+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR006652///Kelch repeat type 1","[KLH21_HUMAN|Reviewed]RecName: Full=Kelch-like protein 21;+++[K7ELI0_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466089};+++[K7EMF2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000466479};+++[K7ESH2_HUMAN|Unreviewed]SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000468710}; Flags: Fragment;+++[L8E9P8_HUMAN|Unreviewed]SubName: Full=Alternative protein KLHL21 {ECO:0000313|EMBL:CCQ43466.1};+++[Q2NKK7_HUMAN|Unreviewed]SubName: Full=KLHL21 protein {ECO:0000313|EMBL:AAI11767.1}; SubName: Full=Kelch-like protein 21 {ECO:0000313|Ensembl:ENSP00000480631};"]
[9904,"'RBM19'",507,466,486.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0005694///chromosome+++GO:0016020///membrane+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus","GO:0003676///nucleic acid binding+++GO:0003723///RNA binding","GO:0045292///mRNA cis splicing, via spliceosome+++GO:0040019///positive regulation of embryonic development+++GO:0007275///multicellular organism development+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","IPR034418///Probable RNA-binding protein 19, RNA recognition motif 1+++IPR034417///Probable RNA-binding protein 19, RNA recognition motif 2+++IPR003954///RNA recognition motif domain, eukaryote+++IPR000504///RNA recognition motif domain+++IPR034420///Probable RNA-binding protein 19, RNA recognition motif 4+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR035979///RNA-binding domain superfamily+++IPR034419///Probable RNA-binding protein 19, RNA recognition motif 3+++IPR034423///Probable RNA-binding protein 19, RNA recognition motif 5+++IPR034421///Probable RNA-binding protein 19, RNA recognition motif 6","[RBM19_HUMAN|Reviewed]RecName: Full=Probable RNA-binding protein 19; AltName: Full=RNA-binding motif protein 19;+++[A0A024RBL4_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 19, isoform CRA_a {ECO:0000313|EMBL:EAW98063.1};+++[H0YIL2_HUMAN|Unreviewed]SubName: Full=Probable RNA-binding protein 19 {ECO:0000313|Ensembl:ENSP00000449604}; Flags: Fragment;"]
[9905,"'SGSM2'",1224,1580,1402,{"$nulls":4},"GO:0005737///cytoplasm+++GO:0042470///melanosome","GO:0017137///Rab GTPase binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:0034499///late endosome to Golgi transport+++GO:0090630///activation of GTPase activity+++GO:0043547///positive regulation of GTPase activity","IPR037213///RUN domain superfamily+++IPR035969///Rab-GTPase-TBC domain superfamily+++IPR000195///Rab-GTPase-TBC domain+++IPR004012///RUN domain+++IPR037745///Small G protein signalling modulator 1/2, PH domain","[SGSM2_HUMAN|Reviewed]RecName: Full=Small G protein signaling modulator 2; AltName: Full=RUN and TBC1 domain-containing protein 1;+++[B9A6J3_HUMAN|Unreviewed]SubName: Full=RUN and TBC1 domain-containing protein 1 {ECO:0000313|EMBL:BAH16621.1};+++[I3L1Y7_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000459218};+++[I3L361_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000460205}; Flags: Fragment;+++[I3NI18_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000461820}; Flags: Fragment;+++[J3QSA2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000464593}; Flags: Fragment;+++[V9GYD2_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476637}; Flags: Fragment;+++[V9GYJ0_HUMAN|Unreviewed]SubName: Full=Small G protein-signaling modulator 2 {ECO:0000313|Ensembl:ENSP00000476800};"]
[9906,"'SLC35E2A'",476.96,472.31,474.635,{"$nulls":4},"GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0004693///cyclin-dependent protein serine/threonine kinase activity+++GO:0004674///protein serine/threonine kinase activity+++GO:0003723///RNA binding+++GO:0005524///ATP binding+++GO:0004672///protein kinase activity","GO:0006468///protein phosphorylation+++GO:0000278///mitotic cell cycle+++GO:0006915///apoptotic process+++GO:0050684///regulation of mRNA processing+++GO:0006355///regulation of transcription, DNA-templated+++GO:0007346///regulation of mitotic cell cycle+++GO:0008283///cell proliferation+++GO:0001558///regulation of cell growth","IPR004853///Sugar phosphate transporter domain","[S35E2_HUMAN|Reviewed]RecName: Full=Solute carrier family 35 member E2;"]
[9907,"'AP5Z1'",1140,1183.12,1161.56,null,"H00266///Hereditary spastic paraplegia (SPG)",null,null,"GO:0005634///nucleus+++GO:0044599///AP-5 adaptor complex+++GO:0005737///cytoplasm+++GO:0030119///AP-type membrane coat adaptor complex+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck","GO:0005515///protein binding+++GO:0003677///DNA binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006974///cellular response to DNA damage stimulus+++GO:0006355///regulation of transcription, DNA-templated+++GO:0015031///protein transport+++GO:0000724///double-strand break repair via homologous recombination+++GO:0006281///DNA repair+++GO:0016197///endosomal transport","IPR028222///AP-5 complex subunit zeta-1+++IPR030456///Fork head domain conserved site 2+++IPR018122///Fork head domain conserved site1+++IPR036388///Winged helix-like DNA-binding domain superfamily+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR001766///Fork head domain+++IPR011989///Armadillo-like helical","[AP5Z1_HUMAN|Reviewed]RecName: Full=AP-5 complex subunit zeta-1; AltName: Full=Adaptor-related protein complex 5 zeta subunit; Short=Zeta5;+++[A0A024R817_HUMAN|Unreviewed]SubName: Full=KIAA0415 protein, isoform CRA_d {ECO:0000313|EMBL:EAW87298.1};+++[A4D1Z4_HUMAN|Unreviewed]SubName: Full=KIAA0415 gene product {ECO:0000313|EMBL:EAL23965.1};"]
[9908,"'G3BP2'",1799,2216,2007.5,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:1990904///ribonucleoprotein complex","GO:0005515///protein binding+++GO:0003723///RNA binding+++GO:0003729///mRNA binding+++GO:0003676///nucleic acid binding+++GO:0030159///receptor signaling complex scaffold activity","GO:0034063///stress granule assembly+++GO:0007253///cytoplasmic sequestering of NF-kappaB+++GO:0051028///mRNA transport+++GO:0007265///Ras protein signal transduction","IPR034377///Ras GTPase-activating protein-binding protein 2+++IPR032710///NTF2-like domain superfamily+++IPR035979///RNA-binding domain superfamily+++IPR000504///RNA recognition motif domain+++IPR018222///Nuclear transport factor 2, eukaryote+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR002075///Nuclear transport factor 2+++IPR034376///G3BP2, RNA recognition motif+++IPR039539///Ras GTPase-activating protein-binding protein","[G3BP2_HUMAN|Reviewed]RecName: Full=Ras GTPase-activating protein-binding protein 2; Short=G3BP-2; AltName: Full=GAP SH3 domain-binding protein 2;+++[A0A024RDB2_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_b {ECO:0000313|EMBL:EAX05747.1};+++[A0A024RDE5_HUMAN|Unreviewed]SubName: Full=Ras-GTPase activating protein SH3 domain-binding protein 2, isoform CRA_a {ECO:0000313|EMBL:EAX05746.1};+++[D6R9A4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423245}; Flags: Fragment;+++[D6R9X5_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422830}; Flags: Fragment;+++[D6RAC7_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422748}; Flags: Fragment;+++[D6RB17_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424522}; Flags: Fragment;+++[D6RBM9_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000424060}; Flags: Fragment;+++[D6RBR0_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000422614}; Flags: Fragment;+++[D6RBW8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000423960}; Flags: Fragment;+++[D6RE13_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000425122}; Flags: Fragment;+++[D6REX8_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000421621}; Flags: Fragment;+++[D6RGJ4_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426311}; Flags: Fragment;+++[H0YAE3_HUMAN|Unreviewed]SubName: Full=Ras GTPase-activating protein-binding protein 2 {ECO:0000313|Ensembl:ENSP00000426843}; Flags: Fragment;"]
[9909,"'DENND4B'",598,762,680,{"$nulls":4},"GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus","GO:0017112///Rab guanyl-nucleotide exchange factor activity+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032483///regulation of Rab protein signal transduction","IPR005113///uDENN domain+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR002885///Pentatricopeptide repeat+++IPR037516///Tripartite DENN domain+++IPR001194///cDENN domain+++IPR005112///dDENN domain+++IPR023341///MABP domain","[DEN4B_HUMAN|Reviewed]RecName: Full=DENN domain-containing protein 4B;+++[E9PAK5_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000357635}; Flags: Fragment;+++[H0YEF0_HUMAN|Unreviewed]SubName: Full=DENN domain-containing protein 4B {ECO:0000313|Ensembl:ENSP00000435709}; Flags: Fragment;"]
[991,"'CDC20'",22,24,23,"04110///Cell cycle+++04111///Cell cycle - yeast+++05203///Viral carcinogenesis+++04113///Meiosis - yeast+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis+++04114///Oocyte meiosis",null,"M00389///APC/C complex",null,"GO:0005680///anaphase-promoting complex+++GO:0005856///cytoskeleton+++GO:0005829///cytosol+++GO:0032991///protein-containing complex+++GO:0005819///spindle+++GO:0005634///nucleus+++GO:0048471///perinuclear region of cytoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005815///microtubule organizing center+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0010997///anaphase-promoting complex binding+++GO:0005515///protein binding+++GO:0097027///ubiquitin-protein transferase activator activity+++GO:0042826///histone deacetylase binding+++GO:0019899///enzyme binding+++GO:0008022///protein C-terminus binding","GO:0016579///protein deubiquitination+++GO:0050773///regulation of dendrite development+++GO:0051301///cell division+++GO:0090307///mitotic spindle assembly+++GO:0090129///positive regulation of synapse maturation+++GO:0040020///regulation of meiotic nuclear division+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0007399///nervous system development+++GO:1904668///positive regulation of ubiquitin protein ligase activity+++GO:0007049///cell cycle+++GO:0031915///positive regulation of synaptic plasticity+++GO:0007094///mitotic spindle assembly checkpoint+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0030154///cell differentiation+++GO:0016567///protein ubiquitination+++GO:0007064///mitotic sister chromatid cohesion+++GO:0008284///positive regulation of cell proliferation","IPR019775///WD40 repeat, conserved site+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR033187///Cell division cycle protein 20 homologue+++IPR024977///Anaphase-promoting complex subunit 4, WD40 domain+++IPR033010///The WD repeat Cdc20/Fizzy family+++IPR001680///WD40 repeat+++IPR017986///WD40-repeat-containing domain+++IPR036322///WD40-repeat-containing domain superfamily","[CDC20_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 20 homolog; AltName: Full=p55CDC;"]
[9910,"'RABGAP1L'",348.58,361,354.79,{"$nulls":4},"GO:0005794///Golgi apparatus+++GO:0005929///cilium+++GO:0005769///early endosome+++GO:0005768///endosome+++GO:0005634///nucleus+++GO:0016021///integral component of membrane+++GO:0031410///cytoplasmic vesicle+++GO:0016020///membrane","GO:0017137///Rab GTPase binding+++GO:0005515///protein binding+++GO:0005096///GTPase activator activity","GO:0006886///intracellular protein transport+++GO:1902017///regulation of cilium assembly+++GO:0090630///activation of GTPase activity+++GO:0032880///regulation of protein localization+++GO:0043547///positive regulation of GTPase activity+++GO:0006897///endocytosis+++GO:0015031///protein transport","IPR035969///Rab-GTPase-TBC domain superfamily+++IPR022164///Kinesin-like+++IPR006020///PTB/PI domain+++IPR000195///Rab-GTPase-TBC domain+++IPR011993///PH-like domain superfamily+++IPR033185///Rab GTPase-activating protein 1","[RBG10_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like, isoform 10;+++[RBG1L_HUMAN|Reviewed]RecName: Full=Rab GTPase-activating protein 1-like;+++[A0A0C4DG54_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000403136}; Flags: Fragment;+++[A0A0U1RQT5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489163}; Flags: Fragment;+++[A0A0U1RQV7_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489188}; Flags: Fragment;+++[A0A0U1RQX4_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489213}; Flags: Fragment;+++[A0A0U1RQY6_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489232};+++[A0A0U1RRM5_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000489605};+++[E9PNV2_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000432734};+++[E9PS63_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000435911}; Flags: Fragment;+++[F1LJ00_HUMAN|Unreviewed]SubName: Full=TBC1 domain family, member 18 {ECO:0000313|EMBL:BAH16647.1};+++[F5H8L0_HUMAN|Unreviewed]SubName: Full=Rab GTPase-activating protein 1-like {ECO:0000313|Ensembl:ENSP00000375916};+++[Q9Y3L8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAB41265.1}; Flags: Fragment;"]
[9911,"'TMCC2'",233,296,264.5,{"$nulls":4},"GO:0005783///endoplasmic reticulum+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005515///protein binding","GO:0042982///amyloid precursor protein metabolic process","IPR019394///Testis-specific protein TEX28/transmembrane and coiled-coil domains protein","[TMCC2_HUMAN|Reviewed]RecName: Full=Transmembrane and coiled-coil domains protein 2; AltName: Full=Cerebral protein 11;+++[A0A0C4DFR1_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000331842};+++[A0A1B0GUZ3_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_a {ECO:0000313|EMBL:EAW91545.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000490308};+++[G5E963_HUMAN|Unreviewed]SubName: Full=Transmembrane and coiled-coil domain family 2, isoform CRA_b {ECO:0000313|EMBL:EAW91546.1}; SubName: Full=Transmembrane and coiled-coil domains protein 2 {ECO:0000313|Ensembl:ENSP00000329436};+++[Q8IW47_HUMAN|Unreviewed]SubName: Full=TMCC2 protein {ECO:0000313|EMBL:AAH41019.1}; Flags: Fragment;"]
[9912,"'ARHGAP44'",94,92,93,"03013///RNA transport+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00891///Combined oxidative phosphorylation deficiency (COXPD)",null,null,"GO:0042995///cell projection+++GO:0055037///recycling endosome+++GO:0014069///postsynaptic density+++GO:0005737///cytoplasm+++GO:0045202///synapse+++GO:0098978///glutamatergic synapse+++GO:0043197///dendritic spine+++GO:0005829///cytosol+++GO:0031256///leading edge membrane+++GO:0030054///cell junction+++GO:0048786///presynaptic active zone+++GO:0005768///endosome","GO:0048365///Rac GTPase binding+++GO:0005096///GTPase activator activity+++GO:0005515///protein binding+++GO:0005543///phospholipid binding","GO:0043547///positive regulation of GTPase activity+++GO:0043087///regulation of GTPase activity+++GO:0035021///negative regulation of Rac protein signal transduction+++GO:0007165///signal transduction+++GO:0098886///modification of dendritic spine+++GO:0099010///modification of postsynaptic structure+++GO:0061001///regulation of dendritic spine morphogenesis+++GO:0006887///exocytosis+++GO:0098887///neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0099152///regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051056///regulation of small GTPase mediated signal transduction","IPR008936///Rho GTPase activation protein+++IPR027267///AH/BAR domain superfamily+++IPR004148///BAR domain+++IPR000198///Rho GTPase-activating protein domain","[RHG44_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 44; AltName: Full=NPC-A-10; AltName: Full=Rho-type GTPase-activating protein RICH2; AltName: Full=RhoGAP interacting with CIP4 homologs protein 2; Short=RICH-2;+++[A0A087WZS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000482851};+++[A0A2X0U4K4_HUMAN|Unreviewed]SubName: Full=ARHGAP44 {ECO:0000313|EMBL:SPT35710.1}; Flags: Fragment;+++[E7ERK8_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000262444};+++[F5H6L3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000437542};+++[J3KRS3_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000462141};+++[J3QQU7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000463905}; Flags: Fragment;+++[K7EK86_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 44 {ECO:0000313|Ensembl:ENSP00000465509}; Flags: Fragment;+++[Q69Z00_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp564G2272 {ECO:0000313|EMBL:CAH10728.1}; Flags: Fragment;+++[Q8TBK1_HUMAN|Unreviewed]SubName: Full=RICH2 protein {ECO:0000313|EMBL:AAH22452.3}; Flags: Fragment;"]
[9913,"'SUPT7L'",694,749,721.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0030914///STAGA complex","GO:0005515///protein binding+++GO:0004402///histone acetyltransferase activity+++GO:0003713///transcription coactivator activity+++GO:0046982///protein heterodimerization activity","GO:0043966///histone H3 acetylation+++GO:0051457///maintenance of protein location in nucleus+++GO:1903508///positive regulation of nucleic acid-templated transcription","IPR006565///Bromodomain associated domain+++IPR009072///Histone-fold+++IPR039460///STAGA complex 65 subunit gamma","[ST65G_HUMAN|Reviewed]RecName: Full=STAGA complex 65 subunit gamma; AltName: Full=Adenocarcinoma antigen ART1; AltName: Full=SPTF-associated factor 65 gamma; Short=STAF65gamma; AltName: Full=Suppressor of Ty 7-like;"]
[9914,"'ATP2C2'",0,4,2,null,"H00844///Familial benign chronic pemphigus",null,null,"GO:0031410///cytoplasmic vesicle+++GO:0048471///perinuclear region of cytoplasm+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0005388///calcium-transporting ATPase activity+++GO:0005524///ATP binding+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0015410///manganese-transporting ATPase activity+++GO:0008553///proton-exporting ATPase activity, phosphorylative mechanism+++GO:0046872///metal ion binding+++GO:0016787///hydrolase activity","GO:0090280///positive regulation of calcium ion import+++GO:0099132///ATP hydrolysis coupled cation transmembrane transport+++GO:0072659///protein localization to plasma membrane+++GO:0006874///cellular calcium ion homeostasis+++GO:0070588///calcium ion transmembrane transport+++GO:0006816///calcium ion transport+++GO:0006811///ion transport+++GO:1902600///proton transmembrane transport+++GO:0071421///manganese ion transmembrane transport+++GO:0061180///mammary gland epithelium development","IPR023299///P-type ATPase, cytoplasmic domain N+++IPR036412///HAD-like superfamily+++IPR004014///Cation-transporting P-type ATPase, N-terminal+++IPR030334///Calcium-transporting ATPase type 2C member 2+++IPR006068///Cation-transporting P-type ATPase, C-terminal+++IPR006413///P-type ATPase, subfamily IIA, PMR1-type+++IPR023298///P-type ATPase, transmembrane domain superfamily+++IPR008250///P-type ATPase, A domain superfamily+++IPR023214///HAD superfamily+++IPR001757///P-type ATPase+++IPR018303///P-type ATPase, phosphorylation site","[AT2C2_HUMAN|Reviewed]RecName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000305}; Short=ATPase 2C2; EC=3.6.3.8; AltName: Full=Secretory pathway Ca(2+)-ATPase 2;+++[A0A0A0MSP0_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[B3KR57_HUMAN|Unreviewed]RecName: Full=Calcium-transporting ATPase {ECO:0000256|RuleBase:RU361146}; EC=3.6.3.8 {ECO:0000256|RuleBase:RU361146};+++[H3BS90_HUMAN|Unreviewed]SubName: Full=Calcium-transporting ATPase type 2C member 2 {ECO:0000313|Ensembl:ENSP00000456595}; Flags: Fragment;"]
[9915,"'ARNT2'",229,257,243,"05200///Pathways in cancer+++05211///Renal cell carcinoma+++05202///Transcriptional misregulation in cancer","H01797///Webb-Dattani syndrome",null,null,"GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005667///transcription factor complex+++GO:0005654///nucleoplasm","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046983///protein dimerization activity+++GO:0003677///DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0046982///protein heterodimerization activity+++GO:0017162///aryl hydrocarbon receptor binding+++GO:0005515///protein binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific","GO:0032355///response to estradiol+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0001701///in utero embryonic development+++GO:0008284///positive regulation of cell proliferation+++GO:0043066///negative regulation of apoptotic process+++GO:0007417///central nervous system development+++GO:0007420///brain development+++GO:0001666///response to hypoxia+++GO:0006355///regulation of transcription, DNA-templated+++GO:0006805///xenobiotic metabolic process+++GO:0045944///positive regulation of transcription by RNA polymerase II","IPR035965///PAS domain superfamily+++IPR036638///Helix-loop-helix DNA-binding domain superfamily+++IPR001610///PAC motif+++IPR013767///PAS fold+++IPR000014///PAS domain+++IPR011598///Myc-type, basic helix-loop-helix (bHLH) domain+++IPR013655///PAS fold-3+++IPR001067///Nuclear translocator","[ARNT2_HUMAN|Reviewed]RecName: Full=Aryl hydrocarbon receptor nuclear translocator 2; Short=ARNT protein 2; AltName: Full=Class E basic helix-loop-helix protein 1; Short=bHLHe1;+++[A0A087WVE9_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000479393};+++[H0YKW1_HUMAN|Unreviewed]SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSP00000452961}; Flags: Fragment;+++[Q7Z3A3_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686M216 {ECO:0000313|EMBL:CAD97972.1};+++[Q86TN1_HUMAN|Unreviewed]SubName: Full=ARNT2 protein {ECO:0000313|EMBL:AAH51335.1};+++[X5D7T2_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56635.1};+++[X5D8U0_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform G {ECO:0000313|EMBL:AHW56413.1}; Flags: Fragment;+++[X5D9H9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform B {ECO:0000313|EMBL:AHW56648.1};+++[X5DP31_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform E {ECO:0000313|EMBL:AHW56626.1};+++[X5DP40_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform C {ECO:0000313|EMBL:AHW56636.1};+++[X5DP87_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform F {ECO:0000313|EMBL:AHW56696.1};+++[X5DQN9_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform D {ECO:0000313|EMBL:AHW56412.1}; Flags: Fragment;+++[X5DRE4_HUMAN|Unreviewed]SubName: Full=Aryl-hydrocarbon receptor nuclear translocator 2 isoform H {ECO:0000313|EMBL:AHW56647.1};"]
[9917,"'FAM20B'",507,554,530.5,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0005654///nucleoplasm+++GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0016740///transferase activity+++GO:0016301///kinase activity+++GO:0046872///metal ion binding+++GO:0005524///ATP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding","GO:0006468///protein phosphorylation+++GO:0016310///phosphorylation","IPR009581///FAM20, C-terminal+++IPR024869///FAM20","[XYLK_HUMAN|Reviewed]RecName: Full=Glycosaminoglycan xylosylkinase; EC=2.7.1.- {ECO:0000269|PubMed:19473117}; AltName: Full=Xylose kinase;+++[A0A024R918_HUMAN|Unreviewed]SubName: Full=Family with sequence similarity 20, member B, isoform CRA_a {ECO:0000313|EMBL:EAW91036.1};+++[X6RH03_HUMAN|Unreviewed]SubName: Full=Glycosaminoglycan xylosylkinase {ECO:0000313|Ensembl:ENSP00000404005}; Flags: Fragment;"]
[9918,"'NCAPD2'",511,650,580.5,"04111///Cell cycle - yeast",{"$nulls":3},"GO:0005634///nucleus+++GO:0000796///condensin complex+++GO:0005654///nucleoplasm+++GO:0005694///chromosome+++GO:0000799///nuclear condensin complex+++GO:0000228///nuclear chromosome+++GO:0000793///condensed chromosome+++GO:0016020///membrane+++GO:0000797///condensin core heterodimer+++GO:0005829///cytosol+++GO:0000779///condensed chromosome, centromeric region+++GO:0005737///cytoplasm","GO:0003682///chromatin binding+++GO:0005515///protein binding+++GO:0042393///histone binding","GO:0051304///chromosome separation+++GO:0010032///meiotic chromosome condensation+++GO:0007049///cell cycle+++GO:0030261///chromosome condensation+++GO:0007076///mitotic chromosome condensation+++GO:0051301///cell division+++GO:0000278///mitotic cell cycle","IPR026971///Condensin subunit 1/Condensin-2 complex subunit D3+++IPR016024///Armadillo-type fold+++IPR024324///Condensin complex subunit 1, N-terminal+++IPR011989///Armadillo-like helical+++IPR032682///Condensin complex subunit 1, C-terminal+++IPR007673///Condensin subunit 1","[CND1_HUMAN|Reviewed]RecName: Full=Condensin complex subunit 1; AltName: Full=Chromosome condensation-related SMC-associated protein 1; AltName: Full=Chromosome-associated protein D2; Short=hCAP-D2; AltName: Full=Non-SMC condensin I complex subunit D2; AltName: Full=XCAP-D2 homolog;+++[A0PJ76_HUMAN|Unreviewed]SubName: Full=NCAPD2 protein {ECO:0000313|EMBL:AAH16913.1}; Flags: Fragment;+++[B3KMS0_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[B3KY03_HUMAN|Unreviewed]RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};+++[E7EN77_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000371895}; Flags: Fragment;+++[F5GZK7_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000444377}; Flags: Fragment;+++[F5H431_HUMAN|Unreviewed]SubName: Full=Condensin complex subunit 1 {ECO:0000313|Ensembl:ENSP00000438495};"]
[9919,"'SEC16A'",2846,3865,3355.5,{"$nulls":4},"GO:0012507///ER to Golgi transport vesicle membrane+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0000139///Golgi membrane+++GO:0005783///endoplasmic reticulum+++GO:0043231///intracellular membrane-bounded organelle+++GO:0005794///Golgi apparatus+++GO:0016020///membrane+++GO:0048471///perinuclear region of cytoplasm+++GO:0031090///organelle membrane+++GO:0070971///endoplasmic reticulum exit site+++GO:0005789///endoplasmic reticulum membrane","GO:0005515///protein binding","GO:0007030///Golgi organization+++GO:0032527///protein exit from endoplasmic reticulum+++GO:0043000///Golgi to plasma membrane CFTR protein transport+++GO:0070973///protein localization to endoplasmic reticulum exit site+++GO:0007029///endoplasmic reticulum organization+++GO:0050821///protein stabilization+++GO:0034976///response to endoplasmic reticulum stress+++GO:0015031///protein transport+++GO:0048208///COPII vesicle coating+++GO:0021762///substantia nigra development+++GO:0072659///protein localization to plasma membrane+++GO:0016192///vesicle-mediated transport+++GO:0070863///positive regulation of protein exit from endoplasmic reticulum+++GO:0006888///ER to Golgi vesicle-mediated transport","IPR024298///Ancestral coatomer element 1, Sec16/Sec31+++IPR024340///Sec16, central conserved domain+++IPR024880///COPII coat assembly protein, Sec16","[SC16A_HUMAN|Reviewed]RecName: Full=Protein transport protein Sec16A; AltName: Full=SEC16 homolog A;+++[A0A0C4DH09_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000277537}; Flags: Fragment;+++[A0PJ75_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH16873.1}; Flags: Fragment;+++[A4QN18_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[A4QN19_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;+++[F1T0I1_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[G1UI25_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|EMBL:BAK64148.1}; Flags: Fragment;+++[J3KNL6_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101};+++[Q8N9G1_HUMAN|Unreviewed]SubName: Full=Protein transport protein Sec16A {ECO:0000313|Ensembl:ENSP00000317437}; SubName: Full=cDNA FLJ37437 fis, clone BRAWH2003025 {ECO:0000313|EMBL:BAC04415.1};+++[Q9BV84_HUMAN|Unreviewed]SubName: Full=SEC16A protein {ECO:0000313|EMBL:AAH01404.2}; Flags: Fragment;+++[X6RGP5_HUMAN|Unreviewed]RecName: Full=Protein transport protein sec16 {ECO:0000256|RuleBase:RU364101}; Flags: Fragment;"]
[9920,"'KBTBD11'",339,347,343,{"$nulls":4},"GO:0031463///Cul3-RING ubiquitin ligase complex",null,"GO:0016567///protein ubiquitination","IPR015915///Kelch-type beta propeller+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR000210///BTB/POZ domain+++IPR006652///Kelch repeat type 1","[KBTBB_HUMAN|Reviewed]RecName: Full=Kelch repeat and BTB domain-containing protein 11; AltName: Full=Chronic myelogenous leukemia-associated protein; AltName: Full=Kelch domain-containing protein 7B;"]
[9921,"'RNF10'",2547,2553,2550,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0004842///ubiquitin-protein transferase activity+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0044212///transcription regulatory region DNA binding+++GO:0003677///DNA binding","GO:0051865///protein autoubiquitination+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0031643///positive regulation of myelination+++GO:0010626///negative regulation of Schwann cell proliferation+++GO:0045893///positive regulation of transcription, DNA-templated","IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR001841///Zinc finger, RING-type+++IPR017907///Zinc finger, RING-type, conserved site+++IPR039739///RING-finger protein Mag2/Rnf10","[RNF10_HUMAN|Reviewed]RecName: Full=RING finger protein 10;+++[A0A024RBP0_HUMAN|Unreviewed]SubName: Full=Ring finger protein 10, isoform CRA_a {ECO:0000313|EMBL:EAW98203.1};+++[A0A0G2JKT9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000438638}; Flags: Fragment;+++[F5H3A4_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439221}; Flags: Fragment;+++[F5H510_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000444770}; Flags: Fragment;+++[F5H5P6_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443235}; Flags: Fragment;+++[F5H5Z1_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443000};+++[H0YF69_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000437392}; Flags: Fragment;+++[H0YFN9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439510}; Flags: Fragment;+++[H0YFQ9_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000439859}; Flags: Fragment;+++[H0YG28_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000441487}; Flags: Fragment;+++[H0YGL7_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000443790}; Flags: Fragment;+++[H0YGX5_HUMAN|Unreviewed]SubName: Full=RING finger protein 10 {ECO:0000313|Ensembl:ENSP00000445160}; Flags: Fragment;"]
[9922,"'IQSEC1'",1075,1716,1395.5,"04144///Endocytosis","H00480///Non-syndromic X-linked mental retardation",null,null,"GO:0005737///cytoplasm+++GO:0005730///nucleolus+++GO:0043231///intracellular membrane-bounded organelle+++GO:0016020///membrane+++GO:0005634///nucleus","GO:0005086///ARF guanyl-nucleotide exchange factor activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0005085///guanyl-nucleotide exchange factor activity","GO:0032012///regulation of ARF protein signal transduction+++GO:0051549///positive regulation of keratinocyte migration+++GO:0043547///positive regulation of GTPase activity+++GO:1903393///positive regulation of adherens junction organization+++GO:0030036///actin cytoskeleton organization","IPR000904///Sec7 domain+++IPR030737///IQ motif and SEC7 domain-containing protein 1+++IPR023394///Sec7, C-terminal domain superfamily+++IPR035999///Sec7 domain superfamily+++IPR033742///IQ motif and SEC7 domain-containing protein, PH domain+++IPR000048///IQ motif, EF-hand binding site+++IPR001849///Pleckstrin homology domain+++IPR011993///PH-like domain superfamily","[IQEC1_HUMAN|Reviewed]RecName: Full=IQ motif and SEC7 domain-containing protein 1; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 100; AltName: Full=ADP-ribosylation factors guanine nucleotide-exchange protein 2; AltName: Full=Brefeldin-resistant Arf-GEF 2 protein {ECO:0000303|PubMed:16461286}; Short=BRAG2 {ECO:0000303|PubMed:24058294};+++[A0A087WWK8_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000480301};+++[A0A0C4DGT3_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000478001};+++[A0A2R8Y695_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000495163}; Flags: Fragment;+++[A0A2R8Y7T6_HUMAN|Unreviewed]SubName: Full=IQ motif and SEC7 domain-containing protein 1 {ECO:0000313|Ensembl:ENSP00000496366};+++[B4DGC5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ60491, highly similar to IQ motif and Sec7 domain-containing protein 1 {ECO:0000313|EMBL:BAG57736.1};+++[L0R4Y9_HUMAN|Unreviewed]SubName: Full=Alternative protein IQSEC1 {ECO:0000313|EMBL:CCO13748.1};"]
[9923,"'ZBTB40'",360,539,449.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003677///DNA binding+++GO:0003676///nucleic acid binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003674///molecular_function+++GO:0046872///metal ion binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0030282///bone mineralization+++GO:0006357///regulation of transcription by RNA polymerase II","IPR036236///Zinc finger C2H2 superfamily+++IPR013087///Zinc finger C2H2-type+++IPR030404///Zinc finger and BTB domain-containing protein 40+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR000210///BTB/POZ domain","[ZBT40_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 40;+++[B1AKC8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000383098}; Flags: Fragment;+++[B2RBP0_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 40, isoform CRA_a {ECO:0000313|EMBL:EAW95011.1}; SubName: Full=cDNA, FLJ95610, Homo sapiens KIAA0478 gene product (KIAA0478), mRNA {ECO:0000313|EMBL:BAG37287.1};+++[B3KR52_HUMAN|Unreviewed]SubName: Full=cDNA FLJ33700 fis, clone BRAWH2005074, highly similar to Zinc finger and BTB domain-containing protein 40 {ECO:0000313|EMBL:BAG52264.1}; Flags: Fragment;+++[F8WAI8_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain-containing protein 40 {ECO:0000313|Ensembl:ENSP00000363782};+++[Q1RMZ5_HUMAN|Unreviewed]SubName: Full=ZBTB40 protein {ECO:0000313|EMBL:AAI14608.1};"]
[9924,"'PAN2'",98,163,130.5,"03018///RNA degradation",null,"M00009///Citrate cycle (TCA cycle, Krebs cycle)+++M00010///Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate+++M00740///Methylaspartate cycle+++M00012///Glyoxylate cycle","R00351///acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing) Citrate + CoA <=> Acetyl-CoA + H2O + Oxaloacetate","GO:0000932///P-body+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005739///mitochondrion+++GO:0031251///PAN complex+++GO:0005759///mitochondrial matrix+++GO:0005829///cytosol","GO:0046872///metal ion binding+++GO:0003723///RNA binding+++GO:0004108///citrate (Si)-synthase activity+++GO:0004535///poly(A)-specific ribonuclease activity+++GO:0003676///nucleic acid binding+++GO:0000175///3'-5'-exoribonuclease activity","GO:0010606///positive regulation of cytoplasmic mRNA processing body assembly+++GO:0006397///mRNA processing+++GO:0005975///carbohydrate metabolic process+++GO:0006099///tricarboxylic acid cycle+++GO:0000289///nuclear-transcribed mRNA poly(A) tail shortening","IPR028881///PAN2 domain+++IPR028889///Ubiquitin specific protease domain+++IPR013520///Exonuclease, RNase T/DNA polymerase III+++IPR036322///WD40-repeat-containing domain superfamily+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR036397///Ribonuclease H superfamily+++IPR012337///Ribonuclease H-like superfamily+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR030843///PAN2-PAN3 deadenylation complex catalytic subunit PAN2","[PAN2_HUMAN|Reviewed]RecName: Full=PAN2-PAN3 deadenylation complex catalytic subunit PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}; EC=3.1.13.4 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Inactive ubiquitin carboxyl-terminal hydrolase 52 {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=PAB1P-dependent poly(A)-specific ribonuclease {ECO:0000255|HAMAP-Rule:MF_03182}; AltName: Full=Poly(A)-nuclease deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182}; Short=PAN deadenylation complex subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182};"]
[9925,"'ZBTB5'",186,297,241.5,{"$nulls":4},"GO:0005634///nucleus","GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0005515///protein binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0003677///DNA binding","GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0006974///cellular response to DNA damage stimulus","IPR036236///Zinc finger C2H2 superfamily+++IPR000210///BTB/POZ domain+++IPR011333///SKP1/BTB/POZ domain superfamily+++IPR013087///Zinc finger C2H2-type","[ZBTB5_HUMAN|Reviewed]RecName: Full=Zinc finger and BTB domain-containing protein 5;+++[Q5T942_HUMAN|Unreviewed]SubName: Full=Zinc finger and BTB domain containing 5 {ECO:0000313|EMBL:EAW58282.1}; SubName: Full=cDNA FLJ77230, highly similar to Homo sapiens zinc finger and BTB domain containing 5 (ZBTB5), mRNA {ECO:0000313|EMBL:BAF85093.1};"]
[9926,"'LPGAT1'",235,310,272.5,"00564///Glycerophospholipid metabolism",null,null,"R09036///acyl-CoA:1-acyl-sn-glycero-3-phosphoglycerol O-acyltransferase   Acyl-CoA + 1-Acyl-sn-glycero-3-phosphoglycerol <=> CoA + Phosphatidylglycerol","GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005737///cytoplasm","GO:0047144///2-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0003841///1-acylglycerol-3-phosphate O-acyltransferase activity+++GO:0016746///transferase activity, transferring acyl groups+++GO:0016740///transferase activity+++GO:0003674///molecular_function","GO:0006629///lipid metabolic process+++GO:0045723///positive regulation of fatty acid biosynthetic process+++GO:0036148///phosphatidylglycerol acyl-chain remodeling+++GO:0008654///phospholipid biosynthetic process+++GO:0006644///phospholipid metabolic process","IPR032098///Acyltransferase, C-terminal domain+++IPR002123///Phospholipid/glycerol acyltransferase","[LGAT1_HUMAN|Reviewed]RecName: Full=Acyl-CoA:lysophosphatidylglycerol acyltransferase 1; EC=2.3.1.-;"]
[9927,"'MFN2'",1652,1664,1658,"04137///Mitophagy - animal+++04621///NOD-like receptor signaling pathway+++04214///Apoptosis - fly","H00264///Charcot-Marie-Tooth disease (CMT)",null,null,"GO:0031306///intrinsic component of mitochondrial outer membrane+++GO:0016020///membrane+++GO:0005739///mitochondrion+++GO:0005741///mitochondrial outer membrane+++GO:0016021///integral component of membrane+++GO:0005829///cytosol+++GO:0015630///microtubule cytoskeleton","GO:0003924///GTPase activity+++GO:0005515///protein binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016787///hydrolase activity+++GO:0000166///nucleotide binding+++GO:0005525///GTP binding","GO:0120162///positive regulation of cold-induced thermogenesis+++GO:0001825///blastocyst formation+++GO:0007050///cell cycle arrest+++GO:0006986///response to unfolded protein+++GO:0007596///blood coagulation+++GO:0051646///mitochondrion localization+++GO:0006914///autophagy+++GO:0048593///camera-type eye morphogenesis+++GO:0046580///negative regulation of Ras protein signal transduction+++GO:1904707///positive regulation of vascular smooth muscle cell proliferation+++GO:0061734///parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization+++GO:1905461///positive regulation of vascular associated smooth muscle cell apoptotic process+++GO:0016236///macroautophagy+++GO:0006626///protein targeting to mitochondrion+++GO:0008053///mitochondrial fusion+++GO:0006915///apoptotic process+++GO:0048662///negative regulation of smooth muscle cell proliferation+++GO:0034497///protein localization to phagophore assembly site+++GO:0007006///mitochondrial membrane organization","IPR027089///Mitofusin-2+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR027094///Mitofusin family+++IPR006884///Fzo/mitofusin HR2 domain+++IPR022812///Dynamin superfamily+++IPR030381///Dynamin-type guanine nucleotide-binding (G) domain","[MFN2_HUMAN|Reviewed]RecName: Full=Mitofusin-2; EC=3.6.5.-; AltName: Full=Transmembrane GTPase MFN2;+++[Q5JXC5_HUMAN|Unreviewed]SubName: Full=Mitofusin-2 {ECO:0000313|Ensembl:ENSP00000412023}; Flags: Fragment;"]
[9928,"'KIF14'",4,2,3,null,"H01513///Retinoblastoma+++H00261///Meckel syndrome (MKS)",null,null,"GO:0005874///microtubule+++GO:0005819///spindle+++GO:0030496///midbody+++GO:0005871///kinesin complex+++GO:0016020///membrane+++GO:0090543///Flemming body+++GO:0005634///nucleus+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0005829///cytosol+++GO:0051233///spindle midzone+++GO:0005737///cytoplasm","GO:0008017///microtubule binding+++GO:0016887///ATPase activity+++GO:0000166///nucleotide binding+++GO:0003777///microtubule motor activity+++GO:0015631///tubulin binding+++GO:0030165///PDZ domain binding+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0008574///ATP-dependent microtubule motor activity, plus-end-directed","GO:0021695///cerebellar cortex development+++GO:0010389///regulation of G2/M transition of mitotic cell cycle+++GO:0032467///positive regulation of cytokinesis+++GO:0051301///cell division+++GO:0034446///substrate adhesion-dependent cell spreading+++GO:0032147///activation of protein kinase activity+++GO:0021846///cell proliferation in forebrain+++GO:0033624///negative regulation of integrin activation+++GO:0021693///cerebellar Purkinje cell layer structural organization+++GO:0021772///olfactory bulb development+++GO:0043524///negative regulation of neuron apoptotic process+++GO:0030155///regulation of cell adhesion+++GO:0007080///mitotic metaphase plate congression+++GO:0021766///hippocampus development+++GO:0032487///regulation of Rap protein signal transduction+++GO:0043523///regulation of neuron apoptotic process+++GO:0007019///microtubule depolymerization+++GO:0045184///establishment of protein localization+++GO:2000045///regulation of G1/S transition of mitotic cell cycle+++GO:0021685///cerebellar granular layer structural organization+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0001558///regulation of cell growth+++GO:0008284///positive regulation of cell proliferation+++GO:0031641///regulation of myelination+++GO:0007018///microtubule-based movement+++GO:0030334///regulation of cell migration+++GO:0043066///negative regulation of apoptotic process+++GO:0021987///cerebral cortex development+++GO:1903429///regulation of cell maturation+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process","IPR001752///Kinesin motor domain+++IPR008984///SMAD/FHA domain superfamily+++IPR019821///Kinesin motor domain, conserved site+++IPR036961///Kinesin motor domain superfamily+++IPR027640///Kinesin-like protein+++IPR032405///Kinesin-associated+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR000253///Forkhead-associated (FHA) domain","[KIF14_HUMAN|Reviewed]RecName: Full=Kinesin-like protein KIF14 {ECO:0000305};"]
[9929,"'JOSD1'",730,754.02,742.01,{"$nulls":4},"GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005886///plasma membrane+++GO:0016020///membrane","GO:0016787///hydrolase activity+++GO:0005515///protein binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0008233///peptidase activity","GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","IPR006155///Josephin domain+++IPR040053///Josephin-1/2","[JOS1_HUMAN|Reviewed]RecName: Full=Josephin-1; EC=3.4.19.12; AltName: Full=Josephin domain-containing protein 1;+++[A0A024R1P5_HUMAN|Unreviewed]SubName: Full=Josephin domain containing 1, isoform CRA_a {ECO:0000313|EMBL:EAW60260.1};+++[B0QY55_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000393131}; Flags: Fragment;+++[B0QY56_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000410010}; Flags: Fragment;+++[B0QY57_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000415189}; Flags: Fragment;+++[B0QY58_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000405182}; Flags: Fragment;+++[H0YGT9_HUMAN|Unreviewed]SubName: Full=Josephin-1 {ECO:0000313|Ensembl:ENSP00000444798}; Flags: Fragment;"]
[993,"'CDC25A'",21,27,24,"05206///MicroRNAs in cancer+++04914///Progesterone-mediated oocyte maturation+++04110///Cell cycle+++04218///Cellular senescence",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm","GO:0016787///hydrolase activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0019901///protein kinase binding+++GO:0005515///protein binding+++GO:0051087///chaperone binding","GO:0007049///cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0051301///cell division+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0000086///G2/M transition of mitotic cell cycle+++GO:0016579///protein deubiquitination+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051726///regulation of cell cycle+++GO:0008283///cell proliferation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0009314///response to radiation+++GO:0034644///cellular response to UV","IPR036873///Rhodanese-like domain superfamily+++IPR000751///M-phase inducer phosphatase+++IPR001763///Rhodanese-like domain","[MPIP1_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 1; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25A;+++[A0A024R2R6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_b {ECO:0000313|EMBL:EAW64852.1};+++[A0A024R2S4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25A, isoform CRA_a {ECO:0000313|EMBL:EAW64851.1};+++[C9JFR5_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000416483}; Flags: Fragment;+++[C9JH94_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 1 {ECO:0000313|Ensembl:ENSP00000404285}; Flags: Fragment;+++[D8KXX0_HUMAN|Unreviewed]SubName: Full=CDC25A2-CAG isoform {ECO:0000313|EMBL:ACI43572.1};+++[K7N7S0_HUMAN|Unreviewed]SubName: Full=CDC25 isoform A1-CAG {ECO:0000313|EMBL:ACZ05628.1};"]
[9931,"'HELZ'",472,661,566.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0043186///P granule+++GO:0005829///cytosol+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0005524///ATP binding+++GO:0016787///hydrolase activity+++GO:0004386///helicase activity+++GO:0003723///RNA binding+++GO:0000166///nucleotide binding+++GO:0046872///metal ion binding","GO:0035194///posttranscriptional gene silencing by RNA","IPR036855///Zinc finger, CCCH-type superfamily+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR000571///Zinc finger, CCCH-type+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[HELZ_HUMAN|Reviewed]RecName: Full=Probable helicase with zinc finger domain; EC=3.6.4.-; AltName: Full=Down-regulated in human cancers protein;+++[A0A024R8K8_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger, isoform CRA_a {ECO:0000313|EMBL:EAW89024.1};+++[A0A075B6R3_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000411144};+++[A0A2P0H7U5_HUMAN|Unreviewed]SubName: Full=Helicase with zinc finger {ECO:0000313|EMBL:AAI30583.1};+++[B7ZLW2_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAI44084.1};+++[C1KEM4_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49579.1}; Flags: Fragment;+++[C1KEM5_HUMAN|Unreviewed]SubName: Full=HELZ {ECO:0000313|EMBL:ACO49580.1}; Flags: Fragment;+++[J3KS59_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462320}; Flags: Fragment;+++[J3KT20_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000462763}; Flags: Fragment;+++[J3QRR8_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464354}; Flags: Fragment;+++[J3QS41_HUMAN|Unreviewed]SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|Ensembl:ENSP00000464512};+++[Q6PGP6_HUMAN|Unreviewed]SubName: Full=HELZ protein {ECO:0000313|EMBL:AAH56895.1}; Flags: Fragment;"]
[9933,"'PUM3'",363,344,353.5,{"$nulls":4},"GO:0005634///nucleus+++GO:0005694///chromosome+++GO:0005654///nucleoplasm+++GO:0005730///nucleolus+++GO:0005783///endoplasmic reticulum","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003677///DNA binding","GO:0010835///regulation of protein ADP-ribosylation","IPR011989///Armadillo-like helical+++IPR033133///Pumilio homology domain+++IPR001313///Pumilio RNA-binding repeat+++IPR040059///Pumilio homologue 3+++IPR012959///CPL domain+++IPR016024///Armadillo-type fold","[PUM3_HUMAN|Reviewed]RecName: Full=Pumilio homolog 3 {ECO:0000305}; AltName: Full=HBV X-transactivated gene 5 protein; AltName: Full=HBV XAg-transactivated protein 5; AltName: Full=Minor histocompatibility antigen HA-8; Short=HLA-HA8;+++[Q9NYH5_HUMAN|Unreviewed]SubName: Full=KIAA0020 protein {ECO:0000313|EMBL:AAF69838.1}; Flags: Fragment;+++[S4R3K8_HUMAN|Unreviewed]SubName: Full=Pumilio homolog 3 {ECO:0000313|Ensembl:ENSP00000474467}; Flags: Fragment;"]
[9935,"'MAFB'",54,52,53,"04928///Parathyroid hormone synthesis, secretion and action","H01865///Multicentric carpotarsal osteolysis syndrome",null,null,"GO:0005634///nucleus+++GO:0005667///transcription factor complex","GO:0043565///sequence-specific DNA binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0042803///protein homodimerization activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0046982///protein heterodimerization activity+++GO:0008134///transcription factor binding+++GO:0003677///DNA binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003700///DNA-binding transcription factor activity","GO:0006355///regulation of transcription, DNA-templated+++GO:0007379///segment specification+++GO:0007585///respiratory gaseous exchange+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0042472///inner ear morphogenesis+++GO:0021571///rhombomere 5 development+++GO:0021572///rhombomere 6 development+++GO:0007423///sensory organ development+++GO:0033077///T cell differentiation in thymus+++GO:0035284///brain segmentation+++GO:0021599///abducens nerve formation+++GO:0045647///negative regulation of erythrocyte differentiation+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0045671///negative regulation of osteoclast differentiation+++GO:0048538///thymus development","IPR013592///Maf transcription factor, N-terminal+++IPR004826///Basic leucine zipper domain, Maf-type+++IPR004827///Basic-leucine zipper domain+++IPR024874///Transcription factor Maf family+++IPR028571///Transcription factor MafB+++IPR008917///Transcription factor, Skn-1-like, DNA-binding domain superfamily","[MAFB_HUMAN|Reviewed]RecName: Full=Transcription factor MafB; Short=Maf-B; AltName: Full=V-maf musculoaponeurotic fibrosarcoma oncogene homolog B;+++[L8ECC4_HUMAN|Unreviewed]SubName: Full=Alternative protein MAFB {ECO:0000313|EMBL:CCQ43322.1};"]
[9936,"'CD302'",25,41,33,{"$nulls":4},"GO:0016020///membrane+++GO:0042995///cell projection+++GO:0005737///cytoplasm+++GO:0005902///microvillus+++GO:0030175///filopodium+++GO:0005938///cell cortex+++GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0006909///phagocytosis","IPR001304///C-type lectin-like+++IPR016187///C-type lectin fold+++IPR016186///C-type lectin-like/link domain superfamily","[CD302_HUMAN|Reviewed]RecName: Full=CD302 antigen; AltName: Full=C-type lectin BIMLEC; AltName: Full=C-type lectin domain family 13 member A; AltName: Full=DEC205-associated C-type lectin 1; AltName: Full=Type I transmembrane C-type lectin receptor DCL-1; AltName: CD_antigen=CD302; Flags: Precursor;+++[A0A087WT00_HUMAN|Unreviewed]SubName: Full=CD302 antigen {ECO:0000313|Ensembl:ENSP00000451446};"]
[9937,"'DCLRE1A'",51,57,54,{"$nulls":4},"GO:0000784///nuclear chromosome, telomeric region+++GO:0001650///fibrillar center+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0035312///5'-3' exodeoxyribonuclease activity+++GO:0003684///damaged DNA binding","GO:0006974///cellular response to DNA damage stimulus+++GO:0031848///protection from non-homologous end joining at telomere+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0006281///DNA repair+++GO:0036297///interstrand cross-link repair+++GO:0051301///cell division+++GO:0006303///double-strand break repair via nonhomologous end joining+++GO:0007049///cell cycle","IPR036866///Ribonuclease Z/Hydroxyacylglutathione hydrolase-like+++IPR011084///DNA repair metallo-beta-lactamase","[DCR1A_HUMAN|Reviewed]RecName: Full=DNA cross-link repair 1A protein; AltName: Full=SNM1 homolog A; Short=hSNM1; Short=hSNM1A;"]
[9938,"'ARHGAP25'",2,12,7,{"$nulls":4},"GO:0005829///cytosol+++GO:0001891///phagocytic cup","GO:0005096///GTPase activator activity","GO:0006911///phagocytosis, engulfment+++GO:0007165///signal transduction+++GO:0051058///negative regulation of small GTPase mediated signal transduction+++GO:0043547///positive regulation of GTPase activity+++GO:0007015///actin filament organization+++GO:0051056///regulation of small GTPase mediated signal transduction","IPR008936///Rho GTPase activation protein+++IPR011993///PH-like domain superfamily+++IPR000198///Rho GTPase-activating protein domain+++IPR001849///Pleckstrin homology domain","[RHG25_HUMAN|Reviewed]RecName: Full=Rho GTPase-activating protein 25; AltName: Full=Rho-type GTPase-activating protein 25;+++[A0A2X0TVS2_HUMAN|Unreviewed]SubName: Full=ARHGAP25 {ECO:0000313|EMBL:SPT35696.1}; Flags: Fragment;+++[B7Z8K7_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417283}; SubName: Full=cDNA FLJ59112, highly similar to Rho-GTPase-activating protein 25 {ECO:0000313|EMBL:BAH13993.1};+++[C9JB56_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417467};+++[F8WAV9_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417425};+++[F8WDF6_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000420427};+++[H7C4P1_HUMAN|Unreviewed]SubName: Full=Rho GTPase-activating protein 25 {ECO:0000313|Ensembl:ENSP00000417818}; Flags: Fragment;+++[V9HWC8_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 308 {ECO:0000313|EMBL:ACJ13710.1}; SubName: Full=Rho GTPase activating protein 25, isoform CRA_b {ECO:0000313|EMBL:EAW99867.1};"]
[9939,"'RBM8A'",1434,1175,1304.5,"03015///mRNA surveillance pathway+++03040///Spliceosome+++03013///RNA transport","H01847///Thrombocytopenia-absent radius syndrome","M00430///Exon junction complex (EJC)",null,"GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0016607///nuclear speck+++GO:0005681///spliceosomal complex+++GO:0005829///cytosol+++GO:0043025///neuronal cell body+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:0071013///catalytic step 2 spliceosome+++GO:0035145///exon-exon junction complex","GO:0003723///RNA binding+++GO:0005515///protein binding+++GO:0003676///nucleic acid binding+++GO:0003729///mRNA binding","GO:0031124///mRNA 3'-end processing+++GO:0006417///regulation of translation+++GO:0006396///RNA processing+++GO:0008380///RNA splicing+++GO:0006397///mRNA processing+++GO:0006405///RNA export from nucleus+++GO:0051028///mRNA transport+++GO:0000398///mRNA splicing, via spliceosome+++GO:0006406///mRNA export from nucleus+++GO:0000184///nuclear-transcribed mRNA catabolic process, nonsense-mediated decay+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","IPR035979///RNA-binding domain superfamily+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain+++IPR008111///RNA-binding motif protein 8+++IPR033744///RBM8, RNA recognition motif","[RBM8A_HUMAN|Reviewed]RecName: Full=RNA-binding protein 8A; AltName: Full=Binder of OVCA1-1; Short=BOV-1; AltName: Full=RNA-binding motif protein 8A; AltName: Full=RNA-binding protein Y14; AltName: Full=Ribonucleoprotein RBM8A;+++[A0A023T787_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239};+++[A0A060D9J6_HUMAN|Unreviewed]SubName: Full=RNA binding motif protein 8A {ECO:0000313|EMBL:AIB06359.1}; Flags: Fragment;+++[A0A0J9YW13_HUMAN|Unreviewed]RecName: Full=RNA-binding protein 8A {ECO:0000256|RuleBase:RU361239}; Flags: Fragment;+++[L8E9A7_HUMAN|Unreviewed]SubName: Full=Alternative protein RBM8A {ECO:0000313|EMBL:CCQ43301.1};"]
[994,"'CDC25B'",281,247,264,"04110///Cell cycle+++05206///MicroRNAs in cancer+++04010///MAPK signaling pathway+++04914///Progesterone-mediated oocyte maturation",null,"M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005815///microtubule organizing center+++GO:0005829///cytosol+++GO:0005856///cytoskeleton+++GO:0005654///nucleoplasm+++GO:0000922///spindle pole+++GO:0005813///centrosome+++GO:0005737///cytoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004725///protein tyrosine phosphatase activity+++GO:0016787///hydrolase activity+++GO:0005515///protein binding","GO:0000086///G2/M transition of mitotic cell cycle+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0008284///positive regulation of cell proliferation+++GO:0001556///oocyte maturation+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0007144///female meiosis I+++GO:0007049///cell cycle+++GO:0000278///mitotic cell cycle+++GO:0006470///protein dephosphorylation+++GO:0006468///protein phosphorylation+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0045860///positive regulation of protein kinase activity+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0051301///cell division+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0032467///positive regulation of cytokinesis","IPR000751///M-phase inducer phosphatase+++IPR036873///Rhodanese-like domain superfamily+++IPR001763///Rhodanese-like domain","[MPIP2_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 2; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25B;+++[B3KS38_HUMAN|Unreviewed]SubName: Full=HCG39252, isoform CRA_g {ECO:0000313|EMBL:EAX10500.1}; SubName: Full=Isoform CDC25B6 {ECO:0000313|EMBL:CBX26628.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26628.1}; SubName: Full=cDNA FLJ35394 fis, clone SKNSH2002768, highly similar to M-PHASE INDUCER PHOSPHATASE 2 {ECO:0000313|EMBL:BAG52600.1};+++[B4DIG0_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000339125}; SubName: Full=cDNA FLJ53333, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG58472.1};+++[B4DQZ3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ55479, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61105.1};+++[B4DRC3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56140, highly similar to M-phase inducer phosphatase 2 {ECO:0000313|EMBL:BAG61235.1};+++[E1YMX4_HUMAN|Unreviewed]SubName: Full=Isoform CDC25B7 {ECO:0000313|EMBL:CBX26629.1}; EC=3.1.3.48 {ECO:0000313|EMBL:CBX26629.1};+++[G8JLH2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 2 {ECO:0000313|Ensembl:ENSP00000368918};+++[L8E819_HUMAN|Unreviewed]SubName: Full=Alternative protein CDC25B {ECO:0000313|EMBL:CCQ43259.1};+++[O43550_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94625.1}; Flags: Fragment;+++[Q6MZW8_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686G14213 {ECO:0000313|EMBL:CAE45909.2}; Flags: Fragment;+++[Q7LDQ7_HUMAN|Unreviewed]SubName: Full=Cdc25B phosphatase {ECO:0000313|EMBL:AAB94623.1}; Flags: Fragment;"]
[9940,"'DLEC1'",1,2,1.5,"00592///alpha-Linolenic acid metabolism+++00071///Fatty acid degradation+++01110///Biosynthesis of secondary metabolites+++04146///Peroxisome+++00280///Valine, leucine and isoleucine degradation+++01100///Metabolic pathways+++01130///Biosynthesis of antibiotics+++03320///PPAR signaling pathway+++01040///Biosynthesis of unsaturated fatty acids+++01212///Fatty acid metabolism",null,"M00087///beta-Oxidation+++M00113///Jasmonic acid biosynthesis","R01177///butanoyl-CoA:acetyl-CoA C-butanoyltransferase Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA+++R07953///(4Z,7Z,10Z,13Z,16Z)-Docosapentaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapenta-6,9,12,15,18-enoyl-CoA+++R03858///Lauroyl-CoA:acetyl-CoA C-acyltransferase Lauroyl-CoA + Acetyl-CoA <=> CoA + 3-Oxotetradecanoyl-CoA+++R07891///OPC6-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC8-CoA+++R03991///myristoyl-CoA:acetylCoA C-myristoyltransferase Tetradecanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxopalmitoyl-CoA+++R04546///Propanoyl-CoA + Chenodeoxycholoyl-CoA <=> CoA + 3alpha,7alpha-Dihydroxy-5beta-cholestanoyl-CoA+++R07937///(4Z,7Z,10Z,13Z,16Z,19Z)-Docosahexaenoyl-CoA + Acetyl-CoA <=> CoA + (6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexa-6,9,12,15,18,21-enoyl-CoA+++R03778///Octanoyl-CoA:acetyl-CoA C-acyltransferase Octanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxodecanoyl-CoA+++R00927///acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase; 2-methylacetoacetyl-CoA Propanoyl-CoA + Acetyl-CoA <=> CoA + 2-Methylacetoacetyl-CoA+++R04742///Decanoyl-CoA:acetyl-CoA C-acyltransferase Decanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxododecanoyl-CoA+++R04747///Hexanoyl-CoA:acetyl-CoA C-acyltransferase Hexanoyl-CoA + Acetyl-CoA <=> CoA + 3-Oxooctanoyl-CoA+++R07899///(+)-7-Isojasmonic acid CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC4-CoA+++R07895///OPC4-CoA + Acetyl-CoA <=> CoA + 3-Oxo-OPC6-CoA","GO:0005634///nucleus+++GO:0016020///membrane+++GO:0030864///cortical actin cytoskeleton+++GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0030054///cell junction+++GO:0032587///ruffle membrane+++GO:0005925///focal adhesion+++GO:0005901///caveola","GO:0003674///molecular_function+++GO:0005096///GTPase activator activity+++GO:0008289///lipid binding+++GO:0005515///protein binding+++GO:0042169///SH2 domain binding","GO:0030900///forebrain development+++GO:0008285///negative regulation of cell proliferation+++GO:0021575///hindbrain morphogenesis+++GO:1900119///positive regulation of execution phase of apoptosis+++GO:0008360///regulation of cell shape+++GO:0035023///regulation of Rho protein signal transduction+++GO:0007165///signal transduction+++GO:0003007///heart morphogenesis+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0035307///positive regulation of protein dephosphorylation+++GO:0032956///regulation of actin cytoskeleton organization+++GO:0051895///negative regulation of focal adhesion assembly+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0035024///negative regulation of Rho protein signal transduction+++GO:0030336///negative regulation of cell migration+++GO:0006915///apoptotic process+++GO:0051497///negative regulation of stress fiber assembly+++GO:0048041///focal adhesion assembly+++GO:0001843///neural tube closure+++GO:0030036///actin cytoskeleton organization+++GO:0043547///positive regulation of GTPase activity","IPR000048///IQ motif, EF-hand binding site+++IPR013783///Immunoglobulin-like fold+++IPR033304///Deleted in lung and esophageal cancer protein 1","[DLEC1_HUMAN|Reviewed]RecName: Full=Deleted in lung and esophageal cancer protein 1; AltName: Full=Deleted in lung cancer protein 1; Short=DLC-1;+++[A1L305_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29825.1};+++[A2VDF1_HUMAN|Unreviewed]SubName: Full=DLEC1 protein {ECO:0000313|EMBL:AAI29826.1}; Flags: Fragment;+++[B1B5Y4_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|EMBL:BAG11659.1}; Flags: Fragment;+++[B7ZW06_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 {ECO:0000313|EMBL:AAI71799.1};+++[Q32W76_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 3 {ECO:0000313|EMBL:AAX18635.1}; SubName: Full=Deleted in lung and esophageal cancer protein 1 {ECO:0000313|Ensembl:ENSP00000404261}; Flags: Fragment;+++[Q32W77_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript varient 2 {ECO:0000313|EMBL:AAX18634.1}; Flags: Fragment;+++[Q32W78_HUMAN|Unreviewed]SubName: Full=Deleted in lung and esophageal cancer 1 transcript variant 1 {ECO:0000313|EMBL:AAX18633.1}; Flags: Fragment;"]
[9941,"'EXOG'",141,147,144,{"$nulls":4},"GO:0005739///mitochondrion+++GO:0005743///mitochondrial inner membrane+++GO:0016020///membrane+++GO:0032991///protein-containing complex+++GO:0016021///integral component of membrane","GO:0000014///single-stranded DNA endodeoxyribonuclease activity+++GO:0004519///endonuclease activity+++GO:0004521///endoribonuclease activity+++GO:0004529///exodeoxyribonuclease activity+++GO:0004518///nuclease activity+++GO:0046872///metal ion binding+++GO:0003676///nucleic acid binding+++GO:0016787///hydrolase activity+++GO:0008409///5'-3' exonuclease activity","GO:0090502///RNA phosphodiester bond hydrolysis, endonucleolytic+++GO:0090305///nucleic acid phosphodiester bond hydrolysis+++GO:0000737///DNA catabolic process, endonucleolytic+++GO:0006309///apoptotic DNA fragmentation+++GO:0008150///biological_process","IPR001604///DNA/RNA non-specific endonuclease+++IPR020821///Extracellular Endonuclease, subunit A","[EXOG_HUMAN|Reviewed]RecName: Full=Nuclease EXOG, mitochondrial; EC=3.1.30.-; AltName: Full=Endonuclease G-like 1; Short=Endo G-like 1; Flags: Precursor;+++[A0A024R2T8_HUMAN|Unreviewed]SubName: Full=Endonuclease G-like 1, isoform CRA_b {ECO:0000313|EMBL:EAW64539.1};+++[F2Z2D3_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000400239};+++[F8WC11_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000412756};+++[F8WE28_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000394977};+++[F8WE38_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000402164};+++[F8WEP0_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000413176};+++[H0Y8P1_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000421649}; Flags: Fragment;+++[H7C0W6_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000397124}; Flags: Fragment;+++[H7C451_HUMAN|Unreviewed]SubName: Full=Nuclease EXOG, mitochondrial {ECO:0000313|Ensembl:ENSP00000415568}; Flags: Fragment;"]
[9942,"'XYLB'",41.99,40.96,41.475,"00040///Pentose and glucuronate interconversions+++01100///Metabolic pathways","H00632///Heterotaxy","M00014///Glucuronate pathway (uronate pathway)","R01639///ATP:D-xylulose 5-phosphotransferase   ATP + D-Xylulose <=> ADP + D-Xylulose 5-phosphate","GO:0005737///cytoplasm+++GO:0005829///cytosol","GO:0016301///kinase activity+++GO:0000166///nucleotide binding+++GO:0016740///transferase activity+++GO:0005524///ATP binding+++GO:0016773///phosphotransferase activity, alcohol group as acceptor+++GO:0004856///xylulokinase activity","GO:0005975///carbohydrate metabolic process+++GO:0046835///carbohydrate phosphorylation+++GO:0005997///xylulose metabolic process+++GO:0019640///glucuronate catabolic process to xylulose 5-phosphate+++GO:0016310///phosphorylation+++GO:0005998///xylulose catabolic process+++GO:0006091///generation of precursor metabolites and energy+++GO:0042732///D-xylose metabolic process","IPR000577///Carbohydrate kinase, FGGY+++IPR018484///Carbohydrate kinase, FGGY, N-terminal+++IPR018485///Carbohydrate kinase, FGGY, C-terminal","[XYLB_HUMAN|Reviewed]RecName: Full=Xylulose kinase; Short=Xylulokinase; EC=2.7.1.17;+++[C9J0N9_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000412282};+++[F8WBF6_HUMAN|Unreviewed]SubName: Full=Xylulose kinase {ECO:0000313|Ensembl:ENSP00000398845};+++[Q6PIS3_HUMAN|Unreviewed]SubName: Full=XYLB protein {ECO:0000313|EMBL:AAH30231.1}; Flags: Fragment;"]
[9943,"'OXSR1'",883,1136,1009.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0019898///extrinsic component of membrane+++GO:0070062///extracellular exosome+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm","GO:0003676///nucleic acid binding+++GO:0016740///transferase activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0005524///ATP binding+++GO:0000287///magnesium ion binding+++GO:0042802///identical protein binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000166///nucleotide binding+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0019901///protein kinase binding+++GO:0004674///protein serine/threonine kinase activity+++GO:0004672///protein kinase activity+++GO:0016301///kinase activity","GO:0072143///mesangial cell development+++GO:0036023///embryonic skeletal limb joint morphogenesis+++GO:0002062///chondrocyte differentiation+++GO:1990869///cellular response to chemokine+++GO:0072207///metanephric epithelium development+++GO:0023014///signal transduction by protein phosphorylation+++GO:1901380///negative regulation of potassium ion transmembrane transport+++GO:0001657///ureteric bud development+++GO:0072169///specification of posterior mesonephric tubule identity+++GO:0072168///specification of anterior mesonephric tubule identity+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0060272///embryonic skeletal joint morphogenesis+++GO:0006468///protein phosphorylation+++GO:0007507///heart development+++GO:0072111///cell proliferation involved in kidney development+++GO:0072166///posterior mesonephric tubule development+++GO:0006979///response to oxidative stress+++GO:0001655///urogenital system development+++GO:0032147///activation of protein kinase activity+++GO:0048863///stem cell differentiation+++GO:0048793///pronephros development+++GO:0072234///metanephric nephron tubule development+++GO:0018107///peptidyl-threonine phosphorylation+++GO:0042733///embryonic digit morphogenesis+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0023016///signal transduction by trans-phosphorylation+++GO:0001823///mesonephros development+++GO:0071476///cellular hypotonic response+++GO:2000543///positive regulation of gastrulation+++GO:0072133///metanephric mesenchyme morphogenesis+++GO:0038146///chemokine (C-X-C motif) ligand 12 signaling pathway+++GO:0071300///cellular response to retinoic acid+++GO:0060021///roof of mouth development+++GO:0035116///embryonic hindlimb morphogenesis+++GO:0010820///positive regulation of T cell chemotaxis+++GO:0038116///chemokine (C-C motif) ligand 21 signaling pathway+++GO:0072180///mesonephric duct morphogenesis+++GO:1901017///negative regulation of potassium ion transmembrane transporter activity+++GO:0072190///ureter urothelium development+++GO:0030857///negative regulation of epithelial cell differentiation+++GO:0042474///middle ear morphogenesis+++GO:0072184///renal vesicle progenitor cell differentiation+++GO:0031098///stress-activated protein kinase signaling cascade+++GO:0016310///phosphorylation+++GO:0072259///metanephric interstitial fibroblast development+++GO:0007231///osmosensory signaling pathway+++GO:0030154///cell differentiation+++GO:0035115///embryonic forelimb morphogenesis+++GO:0010628///positive regulation of gene expression+++GO:2000650///negative regulation of sodium ion transmembrane transporter activity+++GO:0072239///metanephric glomerulus vasculature development+++GO:0072162///metanephric mesenchymal cell differentiation+++GO:0072268///pattern specification involved in metanephros development+++GO:0042476///odontogenesis+++GO:0072183///negative regulation of nephron tubule epithelial cell differentiation+++GO:0008406///gonad development+++GO:0072075///metanephric mesenchyme development+++GO:0072498///embryonic skeletal joint development+++GO:1905408///negative regulation of creatine transmembrane transporter activity+++GO:0050679///positive regulation of epithelial cell proliferation+++GO:0072208///metanephric smooth muscle tissue development+++GO:0043066///negative regulation of apoptotic process+++GO:0030501///positive regulation of bone mineralization+++GO:0001656///metanephros development+++GO:0035556///intracellular signal transduction+++GO:0090094///metanephric cap mesenchymal cell proliferation involved in metanephros development+++GO:0046777///protein autophosphorylation+++GO:0048389///intermediate mesoderm development","IPR024678///Serine/threonine-protein kinase OSR1/WNK, CCT domain+++IPR011009///Protein kinase-like domain superfamily+++IPR028749///Serine/threonine-protein kinase OSR1+++IPR000719///Protein kinase domain+++IPR017441///Protein kinase, ATP binding site","[OXSR1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein kinase OSR1; EC=2.7.11.1; AltName: Full=Oxidative stress-responsive 1 protein;+++[A0A024R2M7_HUMAN|Unreviewed]SubName: Full=Oxidative-stress responsive 1, isoform CRA_a {ECO:0000313|EMBL:EAW64523.1};+++[C9JIG9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000415851};+++[F8WBK9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein kinase OSR1 {ECO:0000313|Ensembl:ENSP00000398356};+++[L8ECC0_HUMAN|Unreviewed]SubName: Full=Alternative protein OXSR1 {ECO:0000313|EMBL:CCQ43302.1};"]
[9945,"'GFPT2'",35,31,33,"01130///Biosynthesis of antibiotics+++00250///Alanine, aspartate and glutamate metabolism+++00520///Amino sugar and nucleotide sugar metabolism+++04931///Insulin resistance+++01100///Metabolic pathways","H00770///Congenital myasthenic syndrome",null,"R00768///L-glutamine:D-fructose-6-phosphate isomerase (deaminating); L-glutamine:D-fructose-6-phosphate   L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate","GO:0005829///cytosol","GO:0008483///transaminase activity+++GO:0005515///protein binding+++GO:0097367///carbohydrate derivative binding+++GO:0016740///transferase activity+++GO:0004360///glutamine-fructose-6-phosphate transaminase (isomerizing) activity","GO:0006541///glutamine metabolic process+++GO:0006112///energy reserve metabolic process+++GO:0006002///fructose 6-phosphate metabolic process+++GO:1990830///cellular response to leukemia inhibitory factor+++GO:1901135///carbohydrate derivative metabolic process+++GO:0006048///UDP-N-acetylglucosamine biosynthetic process+++GO:0006047///UDP-N-acetylglucosamine metabolic process+++GO:1901137///carbohydrate derivative biosynthetic process+++GO:0006487///protein N-linked glycosylation","IPR001347///Sugar isomerase (SIS)+++IPR035466///GlmS/AgaS, SIS domain 1+++IPR017932///Glutamine amidotransferase type 2 domain+++IPR005855///Glucosamine-fructose-6-phosphate aminotransferase, isomerising+++IPR035490///GlmS/FrlB, SIS domain 2+++IPR029055///Nucleophile aminohydrolases, N-terminal","[GFPT2_HUMAN|Reviewed]RecName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2; EC=2.6.1.16 {ECO:0000250|UniProtKB:P82808}; AltName: Full=D-fructose-6-phosphate amidotransferase 2; AltName: Full=Glutamine:fructose-6-phosphate amidotransferase 2; Short=GFAT 2; Short=GFAT2; AltName: Full=Hexosephosphate aminotransferase 2;+++[A0A0S2Z4W6_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 2 {ECO:0000313|EMBL:ALQ33953.1}; Flags: Fragment;+++[A0A0S2Z4X9_HUMAN|Unreviewed]SubName: Full=Glutamine-fructose-6-phosphate transaminase 2 isoform 1 {ECO:0000313|EMBL:ALQ33952.1}; SubName: Full=Glutamine-fructose-6-phosphate transaminase 2, isoform CRA_b {ECO:0000313|EMBL:EAW53756.1}; Flags: Fragment;+++[B3KMR8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ12445 fis, clone NT2RM1000256, highly similar to Glucosamine--fructose-6-phosphateaminotransferase (isomerizing) 2 {ECO:0000313|EMBL:BAG51080.1};+++[D6RAC1_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000422771}; Flags: Fragment;+++[E5RJP4_HUMAN|Unreviewed]SubName: Full=Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 {ECO:0000313|Ensembl:ENSP00000431125}; Flags: Fragment;"]
[9946,"'CRYZL1'",124,135,129.5,"04137///Mitophagy - animal+++04140///Autophagy - animal","H02132///Microcephaly syndrome",null,null,"GO:0005829///cytosol","GO:0050661///NADP binding+++GO:0016491///oxidoreductase activity+++GO:0003960///NADPH:quinone reductase activity","GO:1901661///quinone metabolic process+++GO:0055114///oxidation-reduction process","IPR036291///NAD(P)-binding domain superfamily+++IPR011032///GroES-like superfamily+++IPR020843///Polyketide synthase, enoylreductase domain","[QORL1_HUMAN|Reviewed]RecName: Full=Quinone oxidoreductase-like protein 1; EC=1.-.-.-; AltName: Full=Protein 4P11; AltName: Full=Quinone oxidoreductase homolog 1; Short=QOH-1; AltName: Full=Zeta-crystallin homolog;+++[A0A0C4DG14_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000389209};+++[A6NHJ8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000355075};+++[A6NMA8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000290244};+++[A6NND8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000370951};+++[A8MZ10_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000382371};+++[C9JAL0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000405510}; Flags: Fragment;+++[C9JNR9_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000408385}; Flags: Fragment;+++[C9JQD0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000402844}; Flags: Fragment;+++[C9JZK8_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399730};+++[C9K0F7_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000387660}; Flags: Fragment;+++[F8WF64_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000399937};+++[H7C0X3_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000397318}; Flags: Fragment;+++[H7C2K1_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000406423}; Flags: Fragment;+++[H7C338_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000409387}; Flags: Fragment;+++[H7C3I5_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000412087}; Flags: Fragment;+++[H7C3S0_HUMAN|Unreviewed]SubName: Full=Quinone oxidoreductase-like protein 1 {ECO:0000313|Ensembl:ENSP00000413513}; Flags: Fragment;+++[Q8TBV9_HUMAN|Unreviewed]SubName: Full=CRYZL1 protein {ECO:0000313|EMBL:AAH22827.1}; Flags: Fragment;"]
[9948,"'WDR1'",11875,10263,11069,null,"H00948///Renal hypouricemia (RHUC)",null,null,"GO:0030054///cell junction+++GO:0030864///cortical actin cytoskeleton+++GO:0042995///cell projection+++GO:0042643///actomyosin, actin portion+++GO:0005884///actin filament+++GO:0005856///cytoskeleton+++GO:0005886///plasma membrane+++GO:0070062///extracellular exosome+++GO:0002102///podosome+++GO:0043209///myelin sheath+++GO:0005576///extracellular region+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0005911///cell-cell junction","GO:0051015///actin filament binding+++GO:0003779///actin binding","GO:0007605///sensory perception of sound+++GO:0045214///sarcomere organization+++GO:0030042///actin filament depolymerization+++GO:0048713///regulation of oligodendrocyte differentiation+++GO:0040011///locomotion+++GO:0002576///platelet degranulation+++GO:0030834///regulation of actin filament depolymerization+++GO:0030036///actin cytoskeleton organization+++GO:0030836///positive regulation of actin filament depolymerization+++GO:0030220///platelet formation+++GO:0002446///neutrophil mediated immunity+++GO:0008360///regulation of cell shape+++GO:0043297///apical junction assembly+++GO:0042247///establishment of planar polarity of follicular epithelium+++GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:0030043///actin filament fragmentation+++GO:0045199///maintenance of epithelial cell apical/basal polarity+++GO:1990266///neutrophil migration+++GO:0030865///cortical cytoskeleton organization","IPR036322///WD40-repeat-containing domain superfamily+++IPR011045///Nitrous oxide reductase, N-terminal+++IPR015943///WD40/YVTN repeat-like-containing domain superfamily+++IPR019775///WD40 repeat, conserved site+++IPR011047///Quinoprotein alcohol dehydrogenase-like superfamily+++IPR001680///WD40 repeat+++IPR017986///WD40-repeat-containing domain+++IPR020472///G-protein beta WD-40 repeat","[WDR1_HUMAN|Reviewed]RecName: Full=WD repeat-containing protein 1; AltName: Full=Actin-interacting protein 1; Short=AIP1; AltName: Full=NORI-1;+++[D6RD66_HUMAN|Unreviewed]SubName: Full=WD repeat-containing protein 1 {ECO:0000313|Ensembl:ENSP00000425481}; Flags: Fragment;+++[L8E9Y5_HUMAN|Unreviewed]SubName: Full=Alternative protein WDR1 {ECO:0000313|EMBL:CCQ43551.1};+++[Q53GN4_HUMAN|Unreviewed]SubName: Full=WD repeat domain 1, isoform CRA_a {ECO:0000313|EMBL:EAW92686.1}; SubName: Full=WD repeat-containing protein 1 isoform 1 variant {ECO:0000313|EMBL:BAD96617.1}; Flags: Fragment;+++[V9HWG7_HUMAN|Unreviewed]SubName: Full=Epididymis secretory protein Li 52 {ECO:0000313|EMBL:ACJ13729.1};"]
[9949,"'AMMECR1'",126,166,146,"04140///Autophagy - animal+++04137///Mitophagy - animal","H02157///Short-rib thoracic dysplasia+++H00511///Short rib-polydactyly syndrome",null,null,"GO:0005634///nucleus","GO:0005515///protein binding","GO:0008150///biological_process","IPR002733///AMMECR1 domain+++IPR036071///AMMECR1 domain superfamily+++IPR023473///AMMECR1+++IPR027485///AMMECR1, N-terminal","[AMMR1_HUMAN|Reviewed]RecName: Full=AMME syndrome candidate gene 1 protein;+++[A0A0S2Z4V0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 1 {ECO:0000313|EMBL:ALQ33954.1}; Flags: Fragment;+++[A0A0S2Z4X0_HUMAN|Unreviewed]SubName: Full=Alport syndrome mental retardation midface hypoplasia and elliptocytosis chromosomal region protein 1 isoform 2 {ECO:0000313|EMBL:ALQ33955.1}; SubName: Full=Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region, gene 1 {ECO:0000313|EMBL:EAX02663.1}; Flags: Fragment;"]
[995,"'CDC25C'",2,0,1,"05206///MicroRNAs in cancer+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation",null,"M00693///Cell cycle - G2/M transition+++M00691///DNA damage-induced cell cycle checkpoints",null,"GO:0005829///cytosol+++GO:0048471///perinuclear region of cytoplasm+++GO:0016607///nuclear speck+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0019901///protein kinase binding+++GO:0004721///phosphoprotein phosphatase activity+++GO:0005515///protein binding+++GO:0050699///WW domain binding+++GO:0016787///hydrolase activity+++GO:0004725///protein tyrosine phosphatase activity","GO:0000086///G2/M transition of mitotic cell cycle+++GO:1902751///positive regulation of cell cycle G2/M phase transition+++GO:0045931///positive regulation of mitotic cell cycle+++GO:0010971///positive regulation of G2/M transition of mitotic cell cycle+++GO:0007283///spermatogenesis+++GO:0051301///cell division+++GO:0006470///protein dephosphorylation+++GO:0008283///cell proliferation+++GO:0000079///regulation of cyclin-dependent protein serine/threonine kinase activity+++GO:0016032///viral process+++GO:0110032///positive regulation of G2/MI transition of meiotic cell cycle+++GO:0035335///peptidyl-tyrosine dephosphorylation+++GO:0006977///DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest+++GO:0007049///cell cycle+++GO:0007088///regulation of mitotic nuclear division","IPR001763///Rhodanese-like domain+++IPR036873///Rhodanese-like domain superfamily+++IPR000751///M-phase inducer phosphatase","[MPIP3_HUMAN|Reviewed]RecName: Full=M-phase inducer phosphatase 3; EC=3.1.3.48; AltName: Full=Dual specificity phosphatase Cdc25C;+++[B4DX61_HUMAN|Unreviewed]SubName: Full=cDNA FLJ56262, highly similar to M-phase inducer phosphatase 3 {ECO:0000313|EMBL:BAG63273.1};+++[D6RD20_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427105}; Flags: Fragment;+++[D6RJC2_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000427251}; Flags: Fragment;+++[H0Y999_HUMAN|Unreviewed]SubName: Full=M-phase inducer phosphatase 3 {ECO:0000313|Ensembl:ENSP00000423525}; Flags: Fragment;+++[Q9H2F0_HUMAN|Unreviewed]SubName: Full=Cell division cycle 25C splice variant 3 {ECO:0000313|EMBL:AAG41886.1}; Flags: Fragment;"]
[9950,"'GOLGA5'",884,804,844,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0031985///Golgi cisterna+++GO:0005794///Golgi apparatus+++GO:0000139///Golgi membrane+++GO:0005801///cis-Golgi network+++GO:0016021///integral component of membrane+++GO:0030133///transport vesicle+++GO:0016020///membrane","GO:0042803///protein homodimerization activity+++GO:0017137///Rab GTPase binding","GO:0007030///Golgi organization+++GO:0048193///Golgi vesicle transport+++GO:0000301///retrograde transport, vesicle recycling within Golgi","IPR019177///Golgin subfamily A member 5","[GOGA5_HUMAN|Reviewed]RecName: Full=Golgin subfamily A member 5; AltName: Full=Cell proliferation-inducing gene 31 protein; AltName: Full=Golgin-84; AltName: Full=Protein Ret-II; AltName: Full=RET-fused gene 5 protein;"]
[9951,"'HS3ST4'",74,86,80,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0000139///Golgi membrane","GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity","GO:0030201///heparan sulfate proteoglycan metabolic process","IPR000863///Sulfotransferase domain+++IPR037359///Heparan sulfate sulfotransferase+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[HS3S4_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 4; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4; Short=3-OST-4; Short=Heparan sulfate 3-O-sulfotransferase 4; Short=h3-OST-4;+++[A5H458_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155}; Flags: Fragment;"]
[9953,"'HS3ST3B1'",744.43,906,825.215,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0016021///integral component of membrane+++GO:0016020///membrane+++GO:0005794///Golgi apparatus+++GO:0005887///integral component of plasma membrane","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0016740///transferase activity","GO:0006477///protein sulfation+++GO:0015012///heparan sulfate proteoglycan biosynthetic process+++GO:0006024///glycosaminoglycan biosynthetic process+++GO:0015015///heparan sulfate proteoglycan biosynthetic process, enzymatic modification","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR037359///Heparan sulfate sulfotransferase+++IPR000863///Sulfotransferase domain","[HS3SB_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; Short=3-OST-3B; Short=Heparan sulfate 3-O-sulfotransferase 3B1; Short=h3-OST-3B;"]
[9955,"'HS3ST3A1'",1214.57,1404,1309.285,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0016020///membrane+++GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane","GO:0033872///[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity+++GO:0016740///transferase activity","GO:0006024///glycosaminoglycan biosynthetic process","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR037359///Heparan sulfate sulfotransferase+++IPR000863///Sulfotransferase domain","[HS3SA_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 3A1; EC=2.8.2.30; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1; Short=3-OST-3A; Short=Heparan sulfate 3-O-sulfotransferase 3A1; Short=h3-OST-3A;+++[J3KSX5_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9956,"'HS3ST2'",29,18,23.5,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0000139///Golgi membrane+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0016020///membrane","GO:0016740///transferase activity+++GO:0033871///[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity+++GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0008146///sulfotransferase activity","GO:0007623///circadian rhythm+++GO:0006024///glycosaminoglycan biosynthetic process","IPR037359///Heparan sulfate sulfotransferase+++IPR000863///Sulfotransferase domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase","[HS3S2_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 2; EC=2.8.2.29; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2; Short=3-OST-2; Short=Heparan sulfate 3-O-sulfotransferase 2; Short=h3-OST-2;+++[H3BMR2_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};"]
[9957,"'HS3ST1'",37,39,38,"00534///Glycosaminoglycan biosynthesis - heparan sulfate / heparin",{"$nulls":3},"GO:0005796///Golgi lumen+++GO:0005794///Golgi apparatus","GO:0008467///[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity+++GO:0016740///transferase activity+++GO:0008146///sulfotransferase activity","GO:0006024///glycosaminoglycan biosynthetic process","IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR000863///Sulfotransferase domain+++IPR037359///Heparan sulfate sulfotransferase","[HS3S1_HUMAN|Reviewed]RecName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1; EC=2.8.2.23; AltName: Full=Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Short=3-OST-1; Short=Heparan sulfate 3-O-sulfotransferase 1; Short=h3-OST-1; Flags: Precursor;+++[A0A024R9R4_HUMAN|Unreviewed]RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155}; EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};+++[E9PDE3_HUMAN|Unreviewed]SubName: Full=Heparan sulfate glucosamine 3-O-sulfotransferase 1 {ECO:0000313|Ensembl:ENSP00000425673}; Flags: Fragment;+++[Q05CH3_HUMAN|Unreviewed]SubName: Full=HS3ST1 protein {ECO:0000313|EMBL:AAH25735.1}; Flags: Fragment;"]
[9958,"'USP15'",377,443,410,"04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0005829///cytosol+++GO:0005739///mitochondrion+++GO:0005634///nucleus","GO:0004197///cysteine-type endopeptidase activity+++GO:0005160///transforming growth factor beta receptor binding+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0042802///identical protein binding+++GO:0046332///SMAD binding+++GO:0005515///protein binding+++GO:0003824///catalytic activity+++GO:0008233///peptidase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0016787///hydrolase activity+++GO:0061649///ubiquitin modification-dependent histone binding+++GO:0008234///cysteine-type peptidase activity","GO:0060389///pathway-restricted SMAD protein phosphorylation+++GO:0006508///proteolysis+++GO:0007179///transforming growth factor beta receptor signaling pathway+++GO:0035520///monoubiquitinated protein deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0030509///BMP signaling pathway+++GO:0035616///histone H2B conserved C-terminal lysine deubiquitination+++GO:0016579///protein deubiquitination","IPR028135///Ubiquitin-like domain, USP-type+++IPR028134///Ubiquitin carboxyl-terminal hydrolase USP4+++IPR035927///DUSP-like superfamily+++IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase+++IPR029346///Ubiquitin carboxyl-terminal hydrolase, C-terminal+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR029071///Ubiquitin-like domain superfamily+++IPR013792///RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta+++IPR018200///Ubiquitin specific protease, conserved site+++IPR006615///Peptidase C19, ubiquitin-specific peptidase, DUSP domain+++IPR028889///Ubiquitin specific protease domain","[UBP15_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 15; EC=3.4.19.12 {ECO:0000269|PubMed:10444327, ECO:0000269|PubMed:16005295, ECO:0000269|PubMed:21947082, ECO:0000269|PubMed:22344298, ECO:0000269|PubMed:24852371, ECO:0000269|PubMed:27368102}; AltName: Full=Deubiquitinating enzyme 15; AltName: Full=Ubiquitin thioesterase 15; AltName: Full=Ubiquitin-specific-processing protease 15; AltName: Full=Unph-2; AltName: Full=Unph4;+++[F8VVY7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000449563}; Flags: Fragment;+++[F8VZG8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446843}; Flags: Fragment;+++[F8W0H4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447603}; Flags: Fragment;+++[H0YH96_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000446559}; Flags: Fragment;+++[H0YHM4_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000447367}; Flags: Fragment;+++[H0YI26_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448372}; Flags: Fragment;+++[H0YI31_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 15 {ECO:0000313|Ensembl:ENSP00000448393}; Flags: Fragment;+++[Q2NL66_HUMAN|Unreviewed]SubName: Full=USP15 protein {ECO:0000313|EMBL:AAI10909.1};"]
[996,"'CDC27'",822,1085,953.5,"04111///Cell cycle - yeast+++04113///Meiosis - yeast+++04114///Oocyte meiosis+++04110///Cell cycle+++04914///Progesterone-mediated oocyte maturation+++05166///HTLV-I infection+++04120///Ubiquitin mediated proteolysis",null,"M00389///APC/C complex",null,"GO:0005654///nucleoplasm+++GO:0005813///centrosome+++GO:0016020///membrane+++GO:0005680///anaphase-promoting complex+++GO:0005876///spindle microtubule+++GO:0016021///integral component of membrane+++GO:0005819///spindle+++GO:0005829///cytosol+++GO:0005634///nucleus+++GO:0005737///cytoplasm","GO:0019903///protein phosphatase binding+++GO:0005515///protein binding","GO:0016567///protein ubiquitination+++GO:0051301///cell division+++GO:0070979///protein K11-linked ubiquitination+++GO:1901990///regulation of mitotic cell cycle phase transition+++GO:0031145///anaphase-promoting complex-dependent catabolic process+++GO:0008283///cell proliferation+++GO:0007091///metaphase/anaphase transition of mitotic cell cycle","IPR001440///Tetratricopeptide repeat 1+++IPR011990///Tetratricopeptide-like helical domain superfamily+++IPR013026///Tetratricopeptide repeat-containing domain+++IPR019734///Tetratricopeptide repeat","[CDC27_HUMAN|Reviewed]RecName: Full=Cell division cycle protein 27 homolog; AltName: Full=Anaphase-promoting complex subunit 3; Short=APC3; AltName: Full=CDC27 homolog; Short=CDC27Hs; AltName: Full=H-NUC;+++[B4DL80_HUMAN|Unreviewed]SubName: Full=cDNA FLJ57525, highly similar to Cell division cycle protein 27 homolog {ECO:0000313|EMBL:BAG59442.1};+++[E9PRZ6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432211};+++[F6QPS0_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000432105};+++[G5EA36_HUMAN|Unreviewed]SubName: Full=Cell division cycle 27, isoform CRA_c {ECO:0000313|EMBL:EAW57688.1}; SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000437339};+++[I0EZ68_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24904.1}; Flags: Fragment;+++[I0EZ72_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 {ECO:0000313|EMBL:AFI24908.1}; Flags: Fragment;+++[I3L1K3_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000458904}; Flags: Fragment;+++[I3L225_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000459307}; Flags: Fragment;+++[I3L2Z8_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460061}; Flags: Fragment;+++[I3L328_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460132}; Flags: Fragment;+++[I3L394_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460279}; Flags: Fragment;+++[I3L3G1_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460424}; Flags: Fragment;+++[I3L3H6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460454}; Flags: Fragment;+++[I3L3Y5_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000460830}; Flags: Fragment;+++[K7EMA6_HUMAN|Unreviewed]SubName: Full=Cell division cycle protein 27 homolog {ECO:0000313|Ensembl:ENSP00000466424};"]
[9960,"'USP3'",124,128,126,"04140///Autophagy - animal+++04137///Mitophagy - animal+++04120///Ubiquitin mediated proteolysis",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0005654///nucleoplasm+++GO:0090543///Flemming body+++GO:0000790///nuclear chromatin+++GO:0005634///nucleus","GO:0046872///metal ion binding+++GO:0008233///peptidase activity+++GO:0036459///thiol-dependent ubiquitinyl hydrolase activity+++GO:0016787///hydrolase activity+++GO:0004843///thiol-dependent ubiquitin-specific protease activity+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0042393///histone binding+++GO:1990841///promoter-specific chromatin binding+++GO:0008234///cysteine-type peptidase activity","GO:0006281///DNA repair+++GO:0031647///regulation of protein stability+++GO:0016578///histone deubiquitination+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016579///protein deubiquitination+++GO:0000278///mitotic cell cycle+++GO:0006325///chromatin organization+++GO:0006974///cellular response to DNA damage stimulus+++GO:0007049///cell cycle+++GO:0006508///proteolysis+++GO:0000122///negative regulation of transcription by RNA polymerase II","IPR018200///Ubiquitin specific protease, conserved site+++IPR038765///Papain-like cysteine peptidase superfamily+++IPR001394///Peptidase C19, ubiquitin carboxyl-terminal hydrolase+++IPR001607///Zinc finger, UBP-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR028889///Ubiquitin specific protease domain","[UBP3_HUMAN|Reviewed]RecName: Full=Ubiquitin carboxyl-terminal hydrolase 3; EC=3.4.19.12; AltName: Full=Deubiquitinating enzyme 3; AltName: Full=Ubiquitin thioesterase 3; AltName: Full=Ubiquitin-specific-processing protease 3;+++[H0YKU8_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000452947}; Flags: Fragment;+++[H0YL81_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453093}; Flags: Fragment;+++[H0YLB7_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453138};+++[H0YLG0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453194}; Flags: Fragment;+++[H0YLJ0_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453228};+++[H0YM72_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453489}; Flags: Fragment;+++[H0YMI4_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};+++[H0YMP6_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453688}; Flags: Fragment;+++[H0YMW1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000453767};+++[H0YNK1_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454043};+++[H0YNX9_HUMAN|Unreviewed]SubName: Full=Ubiquitin carboxyl-terminal hydrolase 3 {ECO:0000313|Ensembl:ENSP00000454197}; Flags: Fragment;+++[Q498Y2_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305}; Flags: Fragment;+++[Q6JHV3_HUMAN|Unreviewed]RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305}; EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};"]
[9961,"'MVP'",4215,3704,3959.5,"01100///Metabolic pathways+++04070///Phosphatidylinositol signaling system+++00562///Inositol phosphate metabolism+++00564///Glycerophospholipid metabolism",null,null,"R01802///CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase CDP-diacylglycerol + myo-Inositol <=> CMP + 1-Phosphatidyl-D-myo-inositol","GO:0048471///perinuclear region of cytoplasm+++GO:0016020///membrane+++GO:0005737///cytoplasm+++GO:0005856///cytoskeleton+++GO:1904813///ficolin-1-rich granule lumen+++GO:0000139///Golgi membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0005576///extracellular region+++GO:0005789///endoplasmic reticulum membrane+++GO:0005643///nuclear pore+++GO:0070062///extracellular exosome+++GO:0005829///cytosol+++GO:0005794///Golgi apparatus+++GO:0005634///nucleus+++GO:0034774///secretory granule lumen","GO:0042802///identical protein binding+++GO:0030246///carbohydrate binding+++GO:0030145///manganese ion binding+++GO:0019901///protein kinase binding+++GO:0019992///diacylglycerol binding+++GO:0003881///CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity+++GO:0019903///protein phosphatase binding+++GO:0043178///alcohol binding","GO:0031953///negative regulation of protein autophosphorylation+++GO:0046341///CDP-diacylglycerol metabolic process+++GO:0006661///phosphatidylinositol biosynthetic process+++GO:0023057///negative regulation of signaling+++GO:0015031///protein transport+++GO:0038127///ERBB signaling pathway+++GO:0051028///mRNA transport+++GO:0043312///neutrophil degranulation+++GO:0061099///negative regulation of protein tyrosine kinase activity","IPR039059///Major vault protein+++IPR002499///Major vault protein, N-terminal+++IPR021870///Major vault protein, shoulder domain","[MVP_HUMAN|Reviewed]RecName: Full=Major vault protein; Short=MVP; AltName: Full=Lung resistance-related protein;+++[Q6LAF4_HUMAN|Unreviewed]SubName: Full=LRP protein {ECO:0000313|EMBL:CAA77211.1}; Flags: Fragment;+++[X5D2M8_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform A {ECO:0000313|EMBL:AHW56524.1}; SubName: Full=Major vault protein, isoform CRA_c {ECO:0000313|EMBL:EAW79981.1}; SubName: Full=Testicular secretory protein Li 30 {ECO:0000313|EMBL:AEE61167.1}; Flags: Fragment;+++[X5D7K9_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform C {ECO:0000313|EMBL:AHW56525.1}; Flags: Fragment;+++[X5DNU0_HUMAN|Unreviewed]SubName: Full=Major vault protein isoform B {ECO:0000313|EMBL:AHW56526.1}; Flags: Fragment;"]
[9962,"'SLC23A2'",526,611,568.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0005737///cytoplasm+++GO:0009925///basal plasma membrane+++GO:0016021///integral component of membrane+++GO:0016324///apical plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0016323///basolateral plasma membrane+++GO:0016020///membrane+++GO:0005886///plasma membrane","GO:0070890///sodium-dependent L-ascorbate transmembrane transporter activity+++GO:0015229///L-ascorbic acid transmembrane transporter activity+++GO:0015205///nucleobase transmembrane transporter activity","GO:0006979///response to oxidative stress+++GO:0019852///L-ascorbic acid metabolic process+++GO:0015882///L-ascorbic acid transmembrane transport+++GO:0070904///transepithelial L-ascorbic acid transport+++GO:0006139///nucleobase-containing compound metabolic process+++GO:0015851///nucleobase transport","IPR006043///Xanthine/uracil/vitamin C permease+++IPR006042///Xanthine/uracil permease+++IPR029956///Solute carrier family 23 member 2","[S23A2_HUMAN|Reviewed]RecName: Full=Solute carrier family 23 member 2; AltName: Full=Na(+)/L-ascorbic acid transporter 2; AltName: Full=Nucleobase transporter-like 1 protein; AltName: Full=Sodium-dependent vitamin C transporter 2; Short=hSVCT2; AltName: Full=Yolk sac permease-like molecule 2;+++[A0A140VK48_HUMAN|Unreviewed]SubName: Full=Solute carrier family 23 (Nucleobase transporters), member 2, isoform CRA_b {ECO:0000313|EMBL:EAX10439.1}; SubName: Full=Testicular secretory protein Li 48 {ECO:0000313|EMBL:AEE61185.1};"]
[9966,"'TNFSF15'",1,6.02,3.51,"04060///Cytokine-cytokine receptor interaction","H00286///Crohn's disease",null,null,"GO:0016020///membrane+++GO:0005615///extracellular space+++GO:0005886///plasma membrane+++GO:0005887///integral component of plasma membrane+++GO:0005576///extracellular region+++GO:0016021///integral component of membrane","GO:0005515///protein binding+++GO:0005125///cytokine activity+++GO:0005102///signaling receptor binding+++GO:0005164///tumor necrosis factor receptor binding","GO:0010469///regulation of signaling receptor activity+++GO:0033209///tumor necrosis factor-mediated signaling pathway+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0006915///apoptotic process+++GO:0042107///cytokine metabolic process+++GO:0006955///immune response+++GO:0007250///activation of NF-kappaB-inducing kinase activity+++GO:0007165///signal transduction","IPR006052///Tumour necrosis factor domain+++IPR008983///Tumour necrosis factor-like domain superfamily+++IPR006053///Tumour necrosis factor+++IPR008064///Tumor necrosis factor ligand superfamily member 15","[TNF15_HUMAN|Reviewed]RecName: Full=Tumor necrosis factor ligand superfamily member 15; AltName: Full=TNF ligand-related molecule 1; AltName: Full=Vascular endothelial cell growth inhibitor; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, membrane form; Contains: RecName: Full=Tumor necrosis factor ligand superfamily member 15, secreted form;+++[A0A0U5JA19_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand 1B {ECO:0000313|EMBL:CTQ86078.1};+++[D9N2U0_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor (Ligand) superfamily, member 15 {ECO:0000313|EMBL:BAJ13472.1}; Flags: Fragment;+++[X6R8I9_HUMAN|Unreviewed]SubName: Full=Tumor necrosis factor ligand superfamily member 15 {ECO:0000313|Ensembl:ENSP00000363156};"]
[9967,"'THRAP3'",1430,1643,1536.5,"04140///Autophagy - animal+++04137///Mitophagy - animal",{"$nulls":3},"GO:0016607///nuclear speck+++GO:0035145///exon-exon junction complex+++GO:0005634///nucleus+++GO:0070062///extracellular exosome+++GO:0005654///nucleoplasm+++GO:0016592///mediator complex","GO:0003723///RNA binding+++GO:0042809///vitamin D receptor binding+++GO:0005515///protein binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0051219///phosphoprotein binding+++GO:0003712///transcription coregulator activity+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0038023///signaling receptor activity+++GO:0005524///ATP binding+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0042753///positive regulation of circadian rhythm+++GO:0048255///mRNA stabilization+++GO:0006397///mRNA processing+++GO:0007623///circadian rhythm+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0000956///nuclear-transcribed mRNA catabolic process+++GO:0048511///rhythmic process+++GO:0008380///RNA splicing+++GO:0030521///androgen receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0048026///positive regulation of mRNA splicing, via spliceosome+++GO:0000381///regulation of alternative mRNA splicing, via spliceosome","IPR026667///Thyroid hormone receptor-associated protein 3+++IPR029199///THRAP3/BCLAF1 family","[TR150_HUMAN|Reviewed]RecName: Full=Thyroid hormone receptor-associated protein 3; AltName: Full=BCLAF1 and THRAP3 family member 2 {ECO:0000312|HGNC:HGNC:22964}; AltName: Full=Thyroid hormone receptor-associated protein complex 150 kDa component; Short=Trap150;+++[E9PML1_HUMAN|Unreviewed]SubName: Full=Thyroid hormone receptor-associated protein 3 {ECO:0000313|Ensembl:ENSP00000433066}; Flags: Fragment;+++[Q05D20_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH19076.1}; Flags: Fragment;+++[Q6P0P7_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH65519.1}; Flags: Fragment;+++[Q6PJV4_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH10997.1}; Flags: Fragment;+++[Q7Z5U1_HUMAN|Unreviewed]SubName: Full=THRAP3 protein {ECO:0000313|EMBL:AAH54046.1}; Flags: Fragment;"]
[9968,"'MED12'",805,902,853.5,"04919///Thyroid hormone signaling pathway","H01640///Uterine leiomyoma+++H00894///FG syndrome (FGS)+++H00889///MED12-related disorders+++H01795///Blepharophimosis-mental retardation syndrome (BMRS)",null,null,"GO:0005737///cytoplasm+++GO:0000151///ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0030425///dendrite+++GO:1904115///axon cytoplasm+++GO:0005829///cytosol+++GO:0016592///mediator complex+++GO:0016020///membrane+++GO:0005758///mitochondrial intermembrane space+++GO:0031966///mitochondrial membrane+++GO:0005743///mitochondrial inner membrane+++GO:0016021///integral component of membrane+++GO:0030061///mitochondrial crista+++GO:0031314///extrinsic component of mitochondrial inner membrane+++GO:0005654///nucleoplasm+++GO:0005741///mitochondrial outer membrane+++GO:0005739///mitochondrion","GO:0003682///chromatin binding+++GO:1901612///cardiolipin binding+++GO:0016787///hydrolase activity+++GO:0008017///microtubule binding+++GO:0042809///vitamin D receptor binding+++GO:0008289///lipid binding+++GO:0019904///protein domain specific binding+++GO:0070300///phosphatidic acid binding+++GO:0061630///ubiquitin protein ligase activity+++GO:0008134///transcription factor binding+++GO:0008013///beta-catenin binding+++GO:0008022///protein C-terminus binding+++GO:0005515///protein binding+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000287///magnesium ion binding+++GO:0003712///transcription coregulator activity+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0003924///GTPase activity+++GO:0038023///signaling receptor activity+++GO:0019900///kinase binding+++GO:0005525///GTP binding+++GO:0003713///transcription coactivator activity+++GO:0000166///nucleotide binding+++GO:0046966///thyroid hormone receptor binding","GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0051602///response to electrical stimulus+++GO:1902236///negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway+++GO:0050896///response to stimulus+++GO:0006915///apoptotic process+++GO:0014003///oligodendrocyte development+++GO:0007601///visual perception+++GO:0090398///cellular senescence+++GO:0008053///mitochondrial fusion+++GO:0048312///intracellular distribution of mitochondria+++GO:0007568///aging+++GO:0019896///axonal transport of mitochondrion+++GO:0090102///cochlea development+++GO:0060070///canonical Wnt signaling pathway+++GO:0021510///spinal cord development+++GO:0048702///embryonic neurocranium morphogenesis+++GO:0070584///mitochondrion morphogenesis+++GO:0048568///embryonic organ development+++GO:0036342///post-anal tail morphogenesis+++GO:0019827///stem cell population maintenance+++GO:0030521///androgen receptor signaling pathway+++GO:0097749///membrane tubulation+++GO:0036444///calcium import into the mitochondrion+++GO:0030178///negative regulation of Wnt signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0006357///regulation of transcription by RNA polymerase II+++GO:0000002///mitochondrial genome maintenance+++GO:0016567///protein ubiquitination+++GO:0021915///neural tube development+++GO:0071333///cellular response to glucose stimulus+++GO:0007492///endoderm development+++GO:0061025///membrane fusion+++GO:0051259///protein complex oligomerization+++GO:0001843///neural tube closure+++GO:0071456///cellular response to hypoxia+++GO:0060041///retina development in camera-type eye+++GO:0090201///negative regulation of release of cytochrome c from mitochondria+++GO:0003374///dynamin family protein polymerization involved in mitochondrial fission+++GO:0046039///GTP metabolic process+++GO:1900006///positive regulation of dendrite development+++GO:0090245///axis elongation involved in somitogenesis+++GO:0007507///heart development+++GO:0000266///mitochondrial fission+++GO:1990403///embryonic brain development+++GO:1900078///positive regulation of cellular response to insulin stimulus+++GO:0007007///inner mitochondrial membrane organization+++GO:0014044///Schwann cell development+++GO:0014850///response to muscle activity+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:1905232///cellular response to L-glutamate+++GO:0031667///response to nutrient levels+++GO:0001756///somitogenesis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:1904643///response to curcumin+++GO:0043066///negative regulation of apoptotic process+++GO:0014042///positive regulation of neuron maturation+++GO:0061003///positive regulation of dendritic spine morphogenesis+++GO:0007005///mitochondrion organization+++GO:0046628///positive regulation of insulin receptor signaling pathway+++GO:0010636///positive regulation of mitochondrial fusion","IPR021989///Mediator complex, subunit Med12, catenin-binding+++IPR019035///Mediator complex, subunit Med12+++IPR021990///Mediator complex, subunit Med12, LCEWAV-domain","[MED12_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 12; AltName: Full=Activator-recruited cofactor 240 kDa component; Short=ARC240; AltName: Full=CAG repeat protein 45; AltName: Full=Mediator complex subunit 12; AltName: Full=OPA-containing protein; AltName: Full=Thyroid hormone receptor-associated protein complex 230 kDa component; Short=Trap230; AltName: Full=Trinucleotide repeat-containing gene 11 protein;+++[A0A2R8Y3X5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493673};+++[A0A2R8Y4G4_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494015}; Flags: Fragment;+++[A0A2R8Y4Q3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000493988};+++[A0A2R8Y514_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494210};+++[A0A2R8Y5E2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494736}; Flags: Fragment;+++[A0A2R8Y5G3_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494509};+++[A0A2R8YD53_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494273};+++[A0A2R8YDM2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494725};+++[A0A2R8YE54_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495289};+++[A0A2R8YE78_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000494121};+++[A0A2R8YFD1_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495028}; Flags: Fragment;+++[A0A2R8YGE5_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000495943}; Flags: Fragment;+++[A8MXB6_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376232}; Flags: Fragment;+++[C9JMB8_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000376231};+++[C9JY58_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000399877}; Flags: Fragment;+++[G0KYB4_HUMAN|Unreviewed]SubName: Full=Putative mediator subunit 12 short {ECO:0000313|EMBL:CAZ90628.1}; Flags: Fragment;+++[H7C141_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000398358}; Flags: Fragment;+++[H7C191_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000399084}; Flags: Fragment;+++[H7C274_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000404373}; Flags: Fragment;+++[H7C321_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000409084}; Flags: Fragment;+++[H7C3G2_HUMAN|Unreviewed]SubName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000313|Ensembl:ENSP00000411699}; Flags: Fragment;+++[Q7Z2E0_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81050.1}; Flags: Fragment;+++[Q7Z2F1_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81080.1}; Flags: Fragment;+++[Q7Z2F4_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81020.1}; Flags: Fragment;+++[Q7Z2K3_HUMAN|Unreviewed]SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81092.1}; Flags: Fragment;+++[Q7Z3Z5_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 12 {ECO:0000313|Ensembl:ENSP00000333125}; SubName: Full=Mediator of RNA polymerase II transcription, subunit 12 homolog (Yeast), isoform CRA_e {ECO:0000313|EMBL:EAX05318.1}; SubName: Full=TNRC11 protein {ECO:0000313|EMBL:BAC81137.1};+++[Q8WWP6_HUMAN|Unreviewed]SubName: Full=OPA-containing protein {ECO:0000313|EMBL:CAC84084.1}; Flags: Fragment;"]
[9969,"'MED13'",338,623,480.5,"04919///Thyroid hormone signaling pathway","H00550///Complete transposition of the great arteries",null,null,"GO:0016020///membrane+++GO:0016592///mediator complex+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0003713///transcription coactivator activity+++GO:0042809///vitamin D receptor binding+++GO:0038023///signaling receptor activity+++GO:0003712///transcription coregulator activity+++GO:0046966///thyroid hormone receptor binding+++GO:0030374///nuclear receptor transcription coactivator activity","GO:1904168///negative regulation of thyroid hormone receptor activity+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0030518///intracellular steroid hormone receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030521///androgen receptor signaling pathway+++GO:0042632///cholesterol homeostasis+++GO:0070328///triglyceride homeostasis+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0006357///regulation of transcription by RNA polymerase II","IPR021643///Mediator complex, subunit Med13, N-terminal, metazoa/fungi+++IPR009401///Mediator complex, subunit Med13","[MED13_HUMAN|Reviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13; AltName: Full=Activator-recruited cofactor 250 kDa component; Short=ARC250; AltName: Full=Mediator complex subunit 13; AltName: Full=Thyroid hormone receptor-associated protein 1; AltName: Full=Thyroid hormone receptor-associated protein complex 240 kDa component; Short=Trap240; AltName: Full=Vitamin D3 receptor-interacting protein complex component DRIP250; Short=DRIP250;+++[A0A024QZ75_HUMAN|Unreviewed]RecName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000256|RuleBase:RU364134};+++[J3QRB7_HUMAN|Unreviewed]SubName: Full=Mediator of RNA polymerase II transcription subunit 13 {ECO:0000313|Ensembl:ENSP00000464131}; Flags: Fragment;"]
[997,"'CDC34'",2318,1816,2067,"04120///Ubiquitin mediated proteolysis+++05168///Herpes simplex infection",{"$nulls":3},"GO:0005654///nucleoplasm+++GO:0005634///nucleus+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016607///nuclear speck","GO:0004842///ubiquitin-protein transferase activity+++GO:0016740///transferase activity+++GO:0000166///nucleotide binding+++GO:0005524///ATP binding+++GO:0061631///ubiquitin conjugating enzyme activity+++GO:0005515///protein binding","GO:0035458///cellular response to interferon-beta+++GO:0006270///DNA replication initiation+++GO:0090261///positive regulation of inclusion body assembly+++GO:0043951///negative regulation of cAMP-mediated signaling+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0000082///G1/S transition of mitotic cell cycle+++GO:0051301///cell division+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0070936///protein K48-linked ubiquitination+++GO:0070848///response to growth factor+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0000209///protein polyubiquitination+++GO:0006464///cellular protein modification process+++GO:0007049///cell cycle","IPR000608///Ubiquitin-conjugating enzyme E2+++IPR023313///Ubiquitin-conjugating enzyme, active site+++IPR016135///Ubiquitin-conjugating enzyme/RWD-like","[UB2R1_HUMAN|Reviewed]RecName: Full=Ubiquitin-conjugating enzyme E2 R1; EC=2.3.2.23 {ECO:0000269|PubMed:12037680, ECO:0000269|PubMed:17698585, ECO:0000269|PubMed:20061386, ECO:0000269|PubMed:20347421}; AltName: Full=(E3-independent) E2 ubiquitin-conjugating enzyme R1; EC=2.3.2.24 {ECO:0000269|PubMed:17588522}; AltName: Full=E2 ubiquitin-conjugating enzyme R1; AltName: Full=Ubiquitin-conjugating enzyme E2-32 kDa complementing; AltName: Full=Ubiquitin-conjugating enzyme E2-CDC34; AltName: Full=Ubiquitin-protein ligase R1;+++[A0A024R1Z1_HUMAN|Unreviewed]SubName: Full=Cell division cycle 34, isoform CRA_a {ECO:0000313|EMBL:EAW61191.1};+++[U3KPV8_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475282}; Flags: Fragment;+++[U3KQ77_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000475610}; Flags: Fragment;+++[U3KQP9_HUMAN|Unreviewed]SubName: Full=Ubiquitin-conjugating enzyme E2 R1 {ECO:0000313|Ensembl:ENSP00000476107}; Flags: Fragment;"]
[9972,"'NUP153'",500,666,583,"03013///RNA transport",null,"M00427///Nuclear pore complex",null,"GO:0005634///nucleus+++GO:0005623///cell+++GO:0005730///nucleolus+++GO:0005643///nuclear pore+++GO:0005829///cytosol+++GO:0031965///nuclear membrane+++GO:0005654///nucleoplasm+++GO:0043657///host cell+++GO:0044613///nuclear pore central transport channel+++GO:0034399///nuclear periphery+++GO:0044615///nuclear pore nuclear basket+++GO:0016020///membrane+++GO:0042405///nuclear inclusion body","GO:0017056///structural constituent of nuclear pore+++GO:0043495///protein membrane anchor+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0042802///identical protein binding+++GO:0008139///nuclear localization sequence binding","GO:0075732///viral penetration into host nucleus+++GO:0051028///mRNA transport+++GO:0051292///nuclear pore complex assembly+++GO:0046718///viral entry into host cell+++GO:0015031///protein transport+++GO:0006406///mRNA export from nucleus+++GO:0006606///protein import into nucleus+++GO:0046832///negative regulation of RNA export from nucleus+++GO:0016032///viral process+++GO:0006913///nucleocytoplasmic transport","IPR018892///Retro-transposon transporting motif+++IPR001876///Zinc finger, RanBP2-type+++IPR037625///Nuclear pore complex protein Nup153+++IPR013913///Nucleoporin Nup153, N-terminal+++IPR026054///Nuclear pore complex protein+++IPR036443///Zinc finger, RanBP2-type superfamily","[NU153_HUMAN|Reviewed]RecName: Full=Nuclear pore complex protein Nup153; AltName: Full=153 kDa nucleoporin; AltName: Full=Nucleoporin Nup153;+++[A0A024QZW7_HUMAN|Unreviewed]SubName: Full=Nucleoporin 153kDa, isoform CRA_a {ECO:0000313|EMBL:EAW55385.1};"]
[9973,"'CCS'",223,162,192.5,"05014///Amyotrophic lateral sclerosis (ALS)",{"$nulls":3},"GO:0005615///extracellular space+++GO:0005829///cytosol+++GO:0005737///cytoplasm+++GO:0016021///integral component of membrane+++GO:0005634///nucleus+++GO:0016020///membrane","GO:0005507///copper ion binding+++GO:0005515///protein binding+++GO:0045296///cadherin binding+++GO:0015035///protein disulfide oxidoreductase activity+++GO:0008270///zinc ion binding+++GO:0046872///metal ion binding+++GO:0004784///superoxide dismutase activity+++GO:0016532///superoxide dismutase copper chaperone activity","GO:0015680///protein maturation by copper ion transfer+++GO:0034599///cellular response to oxidative stress+++GO:0051353///positive regulation of oxidoreductase activity+++GO:0055114///oxidation-reduction process+++GO:0006801///superoxide metabolic process+++GO:0019430///removal of superoxide radicals+++GO:0030001///metal ion transport","IPR024134///Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone+++IPR006121///Heavy metal-associated domain, HMA+++IPR018152///Superoxide dismutase, copper/zinc, binding site+++IPR036163///Heavy metal-associated domain superfamily+++IPR036423///Superoxide dismutase-like, copper/zinc binding domain superfamily+++IPR001424///Superoxide dismutase, copper/zinc binding domain","[CCS_HUMAN|Reviewed]RecName: Full=Copper chaperone for superoxide dismutase; AltName: Full=Superoxide dismutase copper chaperone;+++[A0A024R5B4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase, isoform CRA_a {ECO:0000313|EMBL:EAW74551.1};+++[E9PK03_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000433609};+++[E9PP76_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000436379}; Flags: Fragment;+++[J3KNF4_HUMAN|Unreviewed]SubName: Full=Copper chaperone for superoxide dismutase {ECO:0000313|Ensembl:ENSP00000307870};"]
[9975,"'NR1D2'",207,245,226,{"$nulls":4},"GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0090575///RNA polymerase II transcription factor complex","GO:0038023///signaling receptor activity+++GO:0030374///nuclear receptor transcription coactivator activity+++GO:0000987///proximal promoter sequence-specific DNA binding+++GO:0000976///transcription regulatory region sequence-specific DNA binding+++GO:0008270///zinc ion binding+++GO:0000980///RNA polymerase II distal enhancer sequence-specific DNA binding+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding+++GO:0001227///DNA-binding transcription repressor activity, RNA polymerase II-specific+++GO:0005515///protein binding+++GO:0046872///metal ion binding+++GO:0003677///DNA binding+++GO:0008134///transcription factor binding+++GO:0043565///sequence-specific DNA binding+++GO:0003700///DNA-binding transcription factor activity+++GO:0000977///RNA polymerase II regulatory region sequence-specific DNA binding+++GO:0004879///nuclear receptor activity+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0003707///steroid hormone receptor activity","GO:0042752///regulation of circadian rhythm+++GO:0050727///regulation of inflammatory response+++GO:0000122///negative regulation of transcription by RNA polymerase II+++GO:0033993///response to lipid+++GO:2001014///regulation of skeletal muscle cell differentiation+++GO:0048511///rhythmic process+++GO:0097009///energy homeostasis+++GO:0030154///cell differentiation+++GO:0019216///regulation of lipid metabolic process+++GO:0009755///hormone-mediated signaling pathway+++GO:0045892///negative regulation of transcription, DNA-templated+++GO:0006367///transcription initiation from RNA polymerase II promoter+++GO:0055088///lipid homeostasis+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0006355///regulation of transcription, DNA-templated+++GO:0030522///intracellular receptor signaling pathway+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0007275///multicellular organism development+++GO:0043401///steroid hormone mediated signaling pathway","IPR001628///Zinc finger, nuclear hormone receptor-type+++IPR035500///Nuclear hormone receptor-like domain superfamily+++IPR013088///Zinc finger, NHR/GATA-type+++IPR000536///Nuclear hormone receptor, ligand-binding domain+++IPR001723///Nuclear hormone receptor","[NR1D2_HUMAN|Reviewed]RecName: Full=Nuclear receptor subfamily 1 group D member 2; AltName: Full=Orphan nuclear hormone receptor BD73; AltName: Full=Rev-erb alpha-related receptor; Short=RVR; AltName: Full=Rev-erb-beta; AltName: Full=V-erbA-related protein 1-related; Short=EAR-1R;+++[B4DXD3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 2 {ECO:0000313|EMBL:ADZ17342.1}; SubName: Full=Nuclear receptor subfamily 1, group D, member 2, isoform CRA_b {ECO:0000313|EMBL:EAW64341.1}; SubName: Full=cDNA FLJ51368, highly similar to Orphan nuclear receptor NR1D2 {ECO:0000313|EMBL:BAG63345.1};+++[B6ZGS3_HUMAN|Unreviewed]SubName: Full=Nuclear receptor subfamily 1, group D, member 2 {ECO:0000313|EMBL:BAH02284.1};+++[F1D8P2_HUMAN|Unreviewed]SubName: Full=Nuclear receptor Rev-ErbA beta variant 1 {ECO:0000313|EMBL:ADZ17341.1};+++[Q6I9S1_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:CAG33715.1};+++[Q6NSM0_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH70035.1}; SubName: Full=Nuclear receptor subfamily 1 group D member 2 {ECO:0000313|Ensembl:ENSP00000373283};+++[Q96B66_HUMAN|Unreviewed]SubName: Full=NR1D2 protein {ECO:0000313|EMBL:AAH15929.1}; Flags: Fragment;"]
[9978,"'RBX1'",490,414,452,"04110///Cell cycle+++04066///HIF-1 signaling pathway+++05211///Renal cell carcinoma+++04114///Oocyte meiosis+++03420///Nucleotide excision repair+++04120///Ubiquitin mediated proteolysis+++04141///Protein processing in endoplasmic reticulum+++04310///Wnt signaling pathway+++04341///Hedgehog signaling pathway - fly+++05200///Pathways in cancer+++04710///Circadian rhythm+++04350///TGF-beta signaling pathway+++04111///Cell cycle - yeast",null,"M00385///Cul4-DDB1-DDB2 complex+++M00407///SCF-CDC4 complex+++M00381///SCF-SKP2 complex+++M00411///SCF-GRR1 complex+++M00383///ECV complex+++M00382///SCF-FBS complex+++M00386///Cul4-DDB1-CSA complex+++M00380///SCF-BTRC complex+++M00387///SCF-FBW7 complex+++M00384///Cul3-SPOP complex+++M00379///SCF-MET30 complex",null,"GO:0005654///nucleoplasm+++GO:0031466///Cul5-RING ubiquitin ligase complex+++GO:0005737///cytoplasm+++GO:0031467///Cul7-RING ubiquitin ligase complex+++GO:0031465///Cul4B-RING E3 ubiquitin ligase complex+++GO:0005634///nucleus+++GO:0031462///Cul2-RING ubiquitin ligase complex+++GO:0030891///VCB complex+++GO:0031463///Cul3-RING ubiquitin ligase complex+++GO:0005829///cytosol+++GO:0031461///cullin-RING ubiquitin ligase complex+++GO:0031464///Cul4A-RING E3 ubiquitin ligase complex+++GO:0080008///Cul4-RING E3 ubiquitin ligase complex+++GO:0019005///SCF ubiquitin ligase complex+++GO:0043224///nuclear SCF ubiquitin ligase complex","GO:0044877///protein-containing complex binding+++GO:0004842///ubiquitin-protein transferase activity+++GO:0008134///transcription factor binding+++GO:0019788///NEDD8 transferase activity+++GO:0005515///protein binding+++GO:0034450///ubiquitin-ubiquitin ligase activity+++GO:0046872///metal ion binding+++GO:0031625///ubiquitin protein ligase binding+++GO:0016740///transferase activity+++GO:0008270///zinc ion binding+++GO:0097602///cullin family protein binding+++GO:0061630///ubiquitin protein ligase activity","GO:0000715///nucleotide-excision repair, DNA damage recognition+++GO:0070911///global genome nucleotide-excision repair+++GO:0043161///proteasome-mediated ubiquitin-dependent protein catabolic process+++GO:0016032///viral process+++GO:0032436///positive regulation of proteasomal ubiquitin-dependent protein catabolic process+++GO:0006281///DNA repair+++GO:0010265///SCF complex assembly+++GO:0006974///cellular response to DNA damage stimulus+++GO:0006513///protein monoubiquitination+++GO:0006294///nucleotide-excision repair, preincision complex assembly+++GO:0006296///nucleotide-excision repair, DNA incision, 5'-to lesion+++GO:0033683///nucleotide-excision repair, DNA incision+++GO:0043687///post-translational protein modification+++GO:0016055///Wnt signaling pathway+++GO:0006511///ubiquitin-dependent protein catabolic process+++GO:0061418///regulation of transcription from RNA polymerase II promoter in response to hypoxia+++GO:0031146///SCF-dependent proteasomal ubiquitin-dependent protein catabolic process+++GO:0016567///protein ubiquitination+++GO:0070498///interleukin-1-mediated signaling pathway+++GO:0042769///DNA damage response, detection of DNA damage+++GO:0045116///protein neddylation+++GO:0010972///negative regulation of G2/M transition of mitotic cell cycle+++GO:0006293///nucleotide-excision repair, preincision complex stabilization+++GO:0090090///negative regulation of canonical Wnt signaling pathway+++GO:0000209///protein polyubiquitination+++GO:0006283///transcription-coupled nucleotide-excision repair+++GO:0000165///MAPK cascade+++GO:0030163///protein catabolic process","IPR001841///Zinc finger, RING-type+++IPR013083///Zinc finger, RING/FYVE/PHD-type+++IPR024766///Zinc finger, RING-H2-type","[RBX1_HUMAN|Reviewed]RecName: Full=E3 ubiquitin-protein ligase RBX1; EC=2.3.2.27 {ECO:0000269|PubMed:11027288}; EC=2.3.2.32 {ECO:0000269|PubMed:11027288}; AltName: Full=E3 ubiquitin-protein transferase RBX1 {ECO:0000305}; AltName: Full=Protein ZYP; AltName: Full=RING finger protein 75; AltName: Full=RING-box protein 1; Short=Rbx1; AltName: Full=Regulator of cullins 1; Short=ROC1 {ECO:0000303|PubMed:10230407}; Contains: RecName: Full=E3 ubiquitin-protein ligase RBX1, N-terminally processed; AltName: Full=E3 ubiquitin-protein transferase RBX1, N-terminally processed {ECO:0000305};"]
[998,"'CDC42'",3107,2907,3007,"05131///Shigellosis+++05211///Renal cell carcinoma+++04062///Chemokine signaling pathway+++04530///Tight junction+++04932///Non-alcoholic fatty liver disease (NAFLD)+++04810///Regulation of actin cytoskeleton+++05132///Salmonella infection+++05130///Pathogenic Escherichia coli infection+++05205///Proteoglycans in cancer+++04360///Axon guidance+++05165///Human papillomavirus infection+++05212///Pancreatic cancer+++04933///AGE-RAGE signaling pathway in diabetic complications+++05200///Pathways in cancer+++04520///Adherens junction+++04510///Focal adhesion+++04670///Leukocyte transendothelial migration+++04011///MAPK signaling pathway - yeast+++04722///Neurotrophin signaling pathway+++05120///Epithelial cell signaling in Helicobacter pylori infection+++05100///Bacterial invasion of epithelial cells+++04015///Rap1 signaling pathway+++04912///GnRH signaling pathway+++04666///Fc gamma R-mediated phagocytosis+++04014///Ras signaling pathway+++05203///Viral carcinogenesis+++04144///Endocytosis+++04010///MAPK signaling pathway+++04370///VEGF signaling pathway+++04660///T cell receptor signaling pathway",{"$nulls":3},"GO:0045335///phagocytic vesicle+++GO:0043005///neuron projection+++GO:0005813///centrosome+++GO:0005789///endoplasmic reticulum membrane+++GO:0098685///Schaffer collateral - CA1 synapse+++GO:0005911///cell-cell junction+++GO:0005938///cell cortex+++GO:0030141///secretory granule+++GO:0005829///cytosol+++GO:0036464///cytoplasmic ribonucleoprotein granule+++GO:0030496///midbody+++GO:0000139///Golgi membrane+++GO:0045177///apical part of cell+++GO:0031256///leading edge membrane+++GO:0043025///neuronal cell body+++GO:0016020///membrane+++GO:0043209///myelin sheath+++GO:0005856///cytoskeleton+++GO:0005737///cytoplasm+++GO:0005925///focal adhesion+++GO:0042995///cell projection+++GO:0043197///dendritic spine+++GO:0070062///extracellular exosome+++GO:0005819///spindle+++GO:0051233///spindle midzone+++GO:0005886///plasma membrane+++GO:0005815///microtubule organizing center+++GO:0000322///storage vacuole+++GO:0030175///filopodium+++GO:0017119///Golgi transport complex+++GO:0072686///mitotic spindle+++GO:0032991///protein-containing complex+++GO:0071944///cell periphery","GO:0004674///protein serine/threonine kinase activity+++GO:0061630///ubiquitin protein ligase activity+++GO:0005525///GTP binding+++GO:0005515///protein binding+++GO:0000166///nucleotide binding+++GO:0003924///GTPase activity+++GO:0031996///thioesterase binding+++GO:0034191///apolipoprotein A-I receptor binding+++GO:0030742///GTP-dependent protein binding+++GO:0042802///identical protein binding+++GO:0031435///mitogen-activated protein kinase kinase kinase binding+++GO:0032427///GBD domain binding+++GO:0019901///protein kinase binding","GO:0048013///ephrin receptor signaling pathway+++GO:0031274///positive regulation of pseudopodium assembly+++GO:0007097///nuclear migration+++GO:0060047///heart contraction+++GO:0042059///negative regulation of epidermal growth factor receptor signaling pathway+++GO:0099159///regulation of modification of postsynaptic structure+++GO:0051149///positive regulation of muscle cell differentiation+++GO:0072384///organelle transport along microtubule+++GO:0007163///establishment or maintenance of cell polarity+++GO:0048010///vascular endothelial growth factor receptor signaling pathway+++GO:0060501///positive regulation of epithelial cell proliferation involved in lung morphogenesis+++GO:0030154///cell differentiation+++GO:0031295///T cell costimulation+++GO:0090316///positive regulation of intracellular protein transport+++GO:0030031///cell projection assembly+++GO:0045198///establishment of epithelial cell apical/basal polarity+++GO:0030307///positive regulation of cell growth+++GO:0051489///regulation of filopodium assembly+++GO:0060997///dendritic spine morphogenesis+++GO:0031333///negative regulation of protein complex assembly+++GO:1900026///positive regulation of substrate adhesion-dependent cell spreading+++GO:0051496///positive regulation of stress fiber assembly+++GO:0060071///Wnt signaling pathway, planar cell polarity pathway+++GO:0090135///actin filament branching+++GO:0036336///dendritic cell migration+++GO:0007266///Rho protein signal transduction+++GO:0043497///regulation of protein heterodimerization activity+++GO:2000251///positive regulation of actin cytoskeleton reorganization+++GO:0006897///endocytosis+++GO:0007088///regulation of mitotic nuclear division+++GO:0016567///protein ubiquitination+++GO:0006468///protein phosphorylation+++GO:0051491///positive regulation of filopodium assembly+++GO:0051492///regulation of stress fiber assembly+++GO:0051988///regulation of attachment of spindle microtubules to kinetochore+++GO:0032467///positive regulation of cytokinesis+++GO:0030036///actin cytoskeleton organization+++GO:0099563///modification of synaptic structure+++GO:0046330///positive regulation of JNK cascade+++GO:0034332///adherens junction organization+++GO:0035722///interleukin-12-mediated signaling pathway+++GO:0034613///cellular protein localization+++GO:0034329///cell junction assembly+++GO:0007399///nervous system development+++GO:0038096///Fc-gamma receptor signaling pathway involved in phagocytosis+++GO:0006911///phagocytosis, engulfment+++GO:0007015///actin filament organization+++GO:0045740///positive regulation of DNA replication+++GO:0007596///blood coagulation+++GO:0032488///Cdc42 protein signal transduction+++GO:0048664///neuron fate determination+++GO:0007229///integrin-mediated signaling pathway+++GO:0021762///substantia nigra development+++GO:0010592///positive regulation of lamellipodium assembly+++GO:0051647///nucleus localization+++GO:0051835///positive regulation of synapse structural plasticity+++GO:0007030///Golgi organization+++GO:0010591///regulation of lamellipodium assembly+++GO:0030225///macrophage differentiation+++GO:0051056///regulation of small GTPase mediated signal transduction+++GO:0071346///cellular response to interferon-gamma+++GO:0046847///filopodium assembly+++GO:0051683///establishment of Golgi localization+++GO:0008360///regulation of cell shape+++GO:0043525///positive regulation of neuron apoptotic process+++GO:0003161///cardiac conduction system development+++GO:0007264///small GTPase mediated signal transduction+++GO:0035088///establishment or maintenance of apical/basal cell polarity+++GO:0043410///positive regulation of MAPK cascade+++GO:0043552///positive regulation of phosphatidylinositol 3-kinase activity+++GO:0051301///cell division+++GO:0038189///neuropilin signaling pathway+++GO:0002040///sprouting angiogenesis+++GO:0060661///submandibular salivary gland formation+++GO:0043085///positive regulation of catalytic activity","IPR001806///Small GTPase+++IPR003578///Small GTPase Rho+++IPR005225///Small GTP-binding protein domain+++IPR027417///P-loop containing nucleoside triphosphate hydrolase+++IPR037874///Cdc42","[CDC42_HUMAN|Reviewed]RecName: Full=Cell division control protein 42 homolog; AltName: Full=G25K GTP-binding protein; Flags: Precursor;+++[A0A024RAE4_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a {ECO:0000313|EMBL:EAW95004.1};+++[A0A024RAE6_HUMAN|Unreviewed]SubName: Full=Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_c {ECO:0000313|EMBL:EAW95009.1};+++[Q5JYX0_HUMAN|Unreviewed]SubName: Full=Cell division control protein 42 homolog {ECO:0000313|Ensembl:ENSP00000398327}; Flags: Fragment;"]
[9980,"'DOP1B'",387,432,409.5,{"$nulls":4},"GO:0016020///membrane+++GO:0005768///endosome+++GO:0000139///Golgi membrane+++GO:0005829///cytosol+++GO:0005802///trans-Golgi network+++GO:0070062///extracellular exosome+++GO:0005794///Golgi apparatus","GO:0003674///molecular_function","GO:0050890///cognition+++GO:0007275///multicellular organism development+++GO:0007029///endoplasmic reticulum organization+++GO:0015031///protein transport+++GO:0006895///Golgi to endosome transport","IPR007249///Dopey, N-terminal","[DOP2_HUMAN|Reviewed]RecName: Full=Protein dopey-2;+++[F8W8U9_HUMAN|Unreviewed]SubName: Full=DOP1 leucine zipper-like protein B {ECO:0000313|Ensembl:ENSP00000270190}; Flags: Fragment;"]
[9984,"'THOC1'",90,77,83.5,"03040///Spliceosome+++03013///RNA transport",null,"M00405///THC complex+++M00406///TREX complex",null,"GO:0005654///nucleoplasm+++GO:0005829///cytosol+++GO:0045171///intercellular bridge+++GO:0000347///THO complex+++GO:0005634///nucleus+++GO:0000784///nuclear chromosome, telomeric region+++GO:0000445///THO complex part of transcription export complex+++GO:0016363///nuclear matrix+++GO:0005737///cytoplasm+++GO:0000346///transcription export complex+++GO:0016607///nuclear speck","GO:0003723///RNA binding+++GO:0003677///DNA binding+++GO:0005515///protein binding","GO:0006915///apoptotic process+++GO:0051028///mRNA transport+++GO:2000002///negative regulation of DNA damage checkpoint+++GO:0046784///viral mRNA export from host cell nucleus+++GO:0006406///mRNA export from nucleus+++GO:0032784///regulation of DNA-templated transcription, elongation+++GO:0032786///positive regulation of DNA-templated transcription, elongation+++GO:0006405///RNA export from nucleus+++GO:0006397///mRNA processing+++GO:0007165///signal transduction+++GO:0008380///RNA splicing+++GO:0031297///replication fork processing+++GO:0006396///RNA processing+++GO:0000018///regulation of DNA recombination+++GO:0048297///negative regulation of isotype switching to IgA isotypes+++GO:0031124///mRNA 3'-end processing","IPR011029///Death-like domain superfamily+++IPR021861///THO complex, subunit THOC1+++IPR000488///Death domain","[THOC1_HUMAN|Reviewed]RecName: Full=THO complex subunit 1; Short=Tho1; AltName: Full=Nuclear matrix protein p84; Short=p84N5; AltName: Full=hTREX84;+++[A0A087WWS1_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000480460};+++[A0A087WY84_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000481599};+++[J3KRD7_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000461943};+++[J3KT14_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000462757};+++[J3QQZ3_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000463965};+++[R4GMN4_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473276}; Flags: Fragment;+++[R4GN58_HUMAN|Unreviewed]SubName: Full=THO complex subunit 1 {ECO:0000313|Ensembl:ENSP00000473499}; Flags: Fragment;"]
[9985,"'REC8'",3926,3704,3815,"04114///Oocyte meiosis",{"$nulls":3},"GO:0000793///condensed chromosome+++GO:0005634///nucleus+++GO:0000794///condensed nuclear chromosome+++GO:0030893///meiotic cohesin complex+++GO:0000800///lateral element+++GO:0005694///chromosome+++GO:0000228///nuclear chromosome+++GO:0000775///chromosome, centromeric region+++GO:0000795///synaptonemal complex+++GO:0000778///condensed nuclear chromosome kinetochore+++GO:0000780///condensed nuclear chromosome, centromeric region+++GO:0008278///cohesin complex+++GO:0001673///male germ cell nucleus+++GO:0034991///nuclear meiotic cohesin complex","GO:0003682///chromatin binding","GO:0007130///synaptonemal complex assembly+++GO:0009566///fertilization+++GO:0000724///double-strand break repair via homologous recombination+++GO:0007059///chromosome segregation+++GO:0007141///male meiosis I+++GO:0007062///sister chromatid cohesion+++GO:0072520///seminiferous tubule development+++GO:0007283///spermatogenesis+++GO:0001556///oocyte maturation+++GO:0051321///meiotic cell cycle+++GO:0007131///reciprocal meiotic recombination+++GO:0007286///spermatid development+++GO:0006302///double-strand break repair+++GO:0007129///synapsis","IPR006910///Rad21/Rec8-like protein, N-terminal+++IPR006909///Rad21/Rec8-like protein, C-terminal, eukaryotic+++IPR036390///Winged helix DNA-binding domain superfamily+++IPR039781///Rad21/Rec8-like protein","[REC8_HUMAN|Reviewed]RecName: Full=Meiotic recombination protein REC8 homolog; AltName: Full=Cohesin Rec8p;+++[A0A075B715_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000452701}; Flags: Fragment;+++[H0YM87_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453506}; Flags: Fragment;+++[H0YMV7_HUMAN|Unreviewed]SubName: Full=Meiotic recombination protein REC8 homolog {ECO:0000313|Ensembl:ENSP00000453763}; Flags: Fragment;"]
[9986,"'RCE1'",216,203,209.5,"01130///Biosynthesis of antibiotics+++00900///Terpenoid backbone biosynthesis",null,null,"R09845///CAAX protease   S-Farnesyl protein + H2O <=> Protein C-terminal S-farnesyl-L-cysteine + Peptide","GO:0005789///endoplasmic reticulum membrane+++GO:0005783///endoplasmic reticulum+++GO:0005887///integral component of plasma membrane+++GO:0016020///membrane+++GO:0016021///integral component of membrane+++GO:0030176///integral component of endoplasmic reticulum membrane+++GO:0005829///cytosol","GO:0008233///peptidase activity+++GO:0004197///cysteine-type endopeptidase activity+++GO:0004222///metalloendopeptidase activity+++GO:0004175///endopeptidase activity+++GO:0016787///hydrolase activity","GO:0071586///CAAX-box protein processing+++GO:0016579///protein deubiquitination+++GO:0006508///proteolysis","IPR003675///CAAX amino terminal protease+++IPR039731///CAAX prenyl protease 2","[FACE2_HUMAN|Reviewed]RecName: Full=CAAX prenyl protease 2; EC=3.4.22.-; AltName: Full=Farnesylated proteins-converting enzyme 2; Short=FACE-2; AltName: Full=Prenyl protein-specific endoprotease 2; AltName: Full=RCE1 homolog; Short=hRCE1;+++[A0A024R5B6_HUMAN|Unreviewed]SubName: Full=RCE1 homolog, prenyl protein peptidase (S. cerevisiae), isoform CRA_a {ECO:0000313|EMBL:EAW74566.1};+++[E9PI08_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436600};+++[E9PKA7_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000435409};+++[E9PPV9_HUMAN|Unreviewed]SubName: Full=CAAX prenyl protease 2 {ECO:0000313|Ensembl:ENSP00000436300};+++[Q0P5W4_HUMAN|Unreviewed]SubName: Full=RCE1 protein {ECO:0000313|EMBL:AAH52622.1}; Flags: Fragment;"]
[9987,"'HNRNPDL'",882,983,932.5,null,"H00593///Limb-girdle muscular dystrophy (LGMD)",null,null,"GO:0005681///spliceosomal complex+++GO:1990904///ribonucleoprotein complex+++GO:0005737///cytoplasm+++GO:0005634///nucleus+++GO:0005654///nucleoplasm+++GO:0005829///cytosol","GO:0043565///sequence-specific DNA binding+++GO:0003697///single-stranded DNA binding+++GO:0005515///protein binding+++GO:0003690///double-stranded DNA binding+++GO:0003677///DNA binding+++GO:0034046///poly(G) binding+++GO:1990837///sequence-specific double-stranded DNA binding+++GO:0003723///RNA binding+++GO:0003676///nucleic acid binding+++GO:0008143///poly(A) binding","GO:0010468///regulation of gene expression+++GO:0006396///RNA processing+++GO:0035722///interleukin-12-mediated signaling pathway","IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR000504///RNA recognition motif domain+++IPR034847///hnRNP DL, RNA recognition motif 1+++IPR035979///RNA-binding domain superfamily","[HNRDL_HUMAN|Reviewed]RecName: Full=Heterogeneous nuclear ribonucleoprotein D-like; Short=hnRNP D-like; Short=hnRNP DL; AltName: Full=AU-rich element RNA-binding factor; AltName: Full=JKT41-binding protein; AltName: Full=Protein laAUF1;+++[A0A024RDF6_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_a {ECO:0000313|EMBL:EAX05891.1};+++[A0A087WU03_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like {ECO:0000313|Ensembl:ENSP00000478269};+++[A0A087WUK2_HUMAN|Unreviewed]SubName: Full=Heterogeneous nuclear ribonucleoprotein D-like, isoform CRA_b {ECO:0000313|EMBL:EAX05890.1};"]
[9988,"'DMTF1'",292,380,336,{"$nulls":4},"GO:0005829///cytosol+++GO:0005788///endoplasmic reticulum lumen+++GO:0005634///nucleus+++GO:0005737///cytoplasm+++GO:0031012///extracellular matrix+++GO:0005654///nucleoplasm+++GO:0005576///extracellular region","GO:0003700///DNA-binding transcription factor activity+++GO:0005178///integrin binding+++GO:0003677///DNA binding+++GO:0005509///calcium ion binding+++GO:0001228///DNA-binding transcription activator activity, RNA polymerase II-specific+++GO:0050840///extracellular matrix binding+++GO:0000981///DNA-binding transcription factor activity, RNA polymerase II-specific+++GO:0000978///RNA polymerase II proximal promoter sequence-specific DNA binding","GO:0006357///regulation of transcription by RNA polymerase II+++GO:0070173///regulation of enamel mineralization+++GO:0031214///biomineral tissue development+++GO:0043687///post-translational protein modification+++GO:0045944///positive regulation of transcription by RNA polymerase II+++GO:0030198///extracellular matrix organization+++GO:0007049///cell cycle+++GO:0044267///cellular protein metabolic process+++GO:0010811///positive regulation of cell-substrate adhesion+++GO:0001503///ossification+++GO:0006355///regulation of transcription, DNA-templated","IPR015495///Myb-like transcription factor+++IPR009057///Homeobox-like domain superfamily+++IPR017930///Myb domain+++IPR001005///SANT/Myb domain+++IPR017877///Myb-like domain","[DMTF1_HUMAN|Reviewed]RecName: Full=Cyclin-D-binding Myb-like transcription factor 1; Short=hDMTF1; AltName: Full=Cyclin-D-interacting Myb-like protein 1; Short=hDMP1;+++[A0A1D5RMP8_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000406384}; Flags: Fragment;+++[B3KMJ8_HUMAN|Unreviewed]SubName: Full=cDNA FLJ11211 fis, clone PLACE1007955, highly similar to Homo sapiens cyclin D binding myb-like transcription factor 1 (DMTF1), mRNA {ECO:0000313|EMBL:BAG51010.1};+++[C9J4F7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000411858}; Flags: Fragment;+++[C9J8Y5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000397490}; Flags: Fragment;+++[C9JED5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000415382}; Flags: Fragment;+++[C9JFR2_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416499}; Flags: Fragment;+++[C9JGT5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000416307}; Flags: Fragment;+++[C9JLR5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413722}; Flags: Fragment;+++[C9JVQ7_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000393370}; Flags: Fragment;+++[C9JZZ6_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000387712}; Flags: Fragment;+++[C9K0K9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000413118}; Flags: Fragment;+++[C9K0L9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000401129}; Flags: Fragment;+++[D6W5P0_HUMAN|Unreviewed]SubName: Full=Cyclin D binding myb-like transcription factor 1, isoform CRA_a {ECO:0000313|EMBL:EAW76964.1};+++[E7EPA0_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000402627};+++[F8VXY9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000448775};+++[H7C388_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000410288}; Flags: Fragment;+++[J3KRC1_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000461920}; Flags: Fragment;+++[J3QKU5_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463239}; Flags: Fragment;+++[J3QLN9_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463638};+++[J3QLW3_HUMAN|Unreviewed]SubName: Full=Cyclin-D-binding Myb-like transcription factor 1 {ECO:0000313|Ensembl:ENSP00000463735}; Flags: Fragment;"]
[9989,"'PPP4R1'",546,653,599.5,"05200///Pathways in cancer+++05212///Pancreatic cancer+++04014///Ras signaling pathway",{"$nulls":3},"GO:0030289///protein phosphatase 4 complex","GO:0005515///protein binding+++GO:0019888///protein phosphatase regulator activity+++GO:0004721///phosphoprotein phosphatase activity+++GO:0004722///protein serine/threonine phosphatase activity","GO:0006470///protein dephosphorylation+++GO:0043666///regulation of phosphoprotein phosphatase activity+++GO:0007165///signal transduction+++GO:0006468///protein phosphorylation+++GO:0050790///regulation of catalytic activity","IPR011989///Armadillo-like helical+++IPR033461///Putative WW-binding domain and destruction box+++IPR016024///Armadillo-type fold+++IPR000357///HEAT repeat+++IPR031087///Serine/threonine-protein phosphatase 4 regulatory subunit 1+++IPR021133///HEAT, type 2","[PP4R1_HUMAN|Reviewed]RecName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1;+++[F8WAJ9_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000285124};+++[J3KRU1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462161}; Flags: Fragment;+++[J3KSB0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462399}; Flags: Fragment;+++[J3KSH2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462485};+++[J3KSS1_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000462621};+++[J3QL26_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463345}; Flags: Fragment;+++[J3QLA6_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463459}; Flags: Fragment;+++[J3QQV0_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000463909}; Flags: Fragment;+++[J3QRV2_HUMAN|Unreviewed]SubName: Full=Serine/threonine-protein phosphatase 4 regulatory subunit 1 {ECO:0000313|Ensembl:ENSP00000464394};+++[Q6RXQ6_HUMAN|Unreviewed]SubName: Full=Protein serine/threonine phosphatase 4 subunit {ECO:0000313|EMBL:AAS59409.1}; Flags: Fragment;"]
[999,"'CDH1'",231,136,183.5,"05218///Melanoma+++05219///Bladder cancer+++05100///Bacterial invasion of epithelial cells+++05200///Pathways in cancer+++05213///Endometrial cancer+++04514///Cell adhesion molecules (CAMs)+++05130///Pathogenic Escherichia coli infection+++04390///Hippo signaling pathway+++04371///Apelin signaling pathway+++04015///Rap1 signaling pathway+++05216///Thyroid cancer+++05226///Gastric cancer+++04520///Adherens junction","H00032///Thyroid cancer+++H00025///Penile cancer+++H00054///Nasopharyngeal cancer+++H00018///Gastric cancer",null,null,"GO:0015629///actin cytoskeleton+++GO:0043296///apical junction complex+++GO:0048471///perinuclear region of cytoplasm+++GO:0030054///cell junction+++GO:0005886///plasma membrane+++GO:0030027///lamellipodium+++GO:0005913///cell-cell adherens junction+++GO:0005576///extracellular region+++GO:0016600///flotillin complex+++GO:0070062///extracellular exosome+++GO:0098978///glutamatergic synapse+++GO:0016021///integral component of membrane+++GO:0098794///postsynapse+++GO:0009898///cytoplasmic side of plasma membrane+++GO:0016342///catenin complex+++GO:0005802///trans-Golgi network+++GO:0005768///endosome+++GO:0016328///lateral plasma membrane","GO:0050839///cell adhesion molecule binding+++GO:0032794///GTPase activating protein binding+++GO:0005509///calcium ion binding+++GO:0030506///ankyrin binding+++GO:0045296///cadherin binding+++GO:0045295///gamma-catenin binding+++GO:0008013///beta-catenin binding+++GO:0042802///identical protein binding","GO:0007156///homophilic cell adhesion via plasma membrane adhesion molecules+++GO:0071681///cellular response to indole-3-methanol+++GO:0099576///regulation of protein catabolic process at postsynapse, modulating synaptic transmission+++GO:0009636///response to toxic substance+++GO:0021983///pituitary gland development+++GO:0007416///synapse assembly+++GO:0045893///positive regulation of transcription, DNA-templated+++GO:0098609///cell-cell adhesion+++GO:0034332///adherens junction organization+++GO:0030336///negative regulation of cell migration+++GO:0042307///positive regulation of protein import into nucleus+++GO:0071285///cellular response to lithium ion+++GO:0035635///entry of bacterium into host cell+++GO:0030198///extracellular matrix organization+++GO:0022408///negative regulation of cell-cell adhesion+++GO:0072659///protein localization to plasma membrane+++GO:0031175///neuron projection development","IPR015919///Cadherin-like superfamily+++IPR002126///Cadherin-like+++IPR000233///Cadherin, cytoplasmic domain+++IPR039808///Cadherin+++IPR027397///Catenin binding domain superfamily+++IPR020894///Cadherin conserved site+++IPR014868///Cadherin prodomain","[CADH1_HUMAN|Reviewed]RecName: Full=Cadherin-1; AltName: Full=CAM 120/80; AltName: Full=Epithelial cadherin; Short=E-cadherin; AltName: Full=Uvomorulin; AltName: CD_antigen=CD324; Contains: RecName: Full=E-Cad/CTF1; Contains: RecName: Full=E-Cad/CTF2; Contains: RecName: Full=E-Cad/CTF3; Flags: Precursor;+++[A0A0U2ZQU7_HUMAN|Unreviewed]SubName: Full=E-cadherin 1 {ECO:0000313|EMBL:ALS87660.1};+++[B3GN61_HUMAN|Unreviewed]SubName: Full=Truncated E-cadherin {ECO:0000313|EMBL:ACD87624.1};+++[Q9UII7_HUMAN|Unreviewed]SubName: Full=E-cadherin {ECO:0000313|EMBL:BAA88957.1};"]
[9990,"'SLC12A6'",310.06,387,348.53,"03008///Ribosome biogenesis in eukaryotes+++04137///Mitophagy - animal+++04140///Autophagy - animal","H00816///Agenesis of the corpus callosum with peripheral neuropathy (ACCPN)+++H01815///Malignant migrating partial seizures in infancy+++H00606///Early infantile epileptic encephalopathy","M00425///H/ACA ribonucleoprotein complex",null,"GO:0016020///membrane+++GO:0005887///integral component of plasma membrane+++GO:0005886///plasma membrane+++GO:0016021///integral component of membrane+++GO:0016323///basolateral plasma membrane","GO:0019901///protein kinase binding+++GO:0015377///cation:chloride symporter activity+++GO:0015293///symporter activity+++GO:0015079///potassium ion transmembrane transporter activity+++GO:0015379///potassium:chloride symporter activity+++GO:0005215///transporter activity","GO:1902476///chloride transmembrane transport+++GO:0055075///potassium ion homeostasis+++GO:0055085///transmembrane transport+++GO:0006884///cell volume homeostasis+++GO:0071476///cellular hypotonic response+++GO:0071477///cellular hypotonic salinity response+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0001525///angiogenesis+++GO:0055064///chloride ion homeostasis+++GO:0007268///chemical synaptic transmission+++GO:1990573///potassium ion import across plasma membrane+++GO:0006813///potassium ion transport","IPR018491///SLC12A transporter, C-terminal+++IPR004842///SLC12A transporter family+++IPR000076///K/Cl co-transporter+++IPR004841///Amino acid permease/ SLC12A domain+++IPR030364///K/Cl co-transporter 3","[S12A6_HUMAN|Reviewed]RecName: Full=Solute carrier family 12 member 6; AltName: Full=Electroneutral potassium-chloride cotransporter 3; AltName: Full=K-Cl cotransporter 3;+++[A0A024R9I5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_d {ECO:0000313|EMBL:EAW92302.1};+++[A0A024R9K8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_a {ECO:0000313|EMBL:EAW92296.1};+++[A7E2U9_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAI50585.1}; Flags: Fragment;+++[B3KXX3_HUMAN|Unreviewed]SubName: Full=cDNA FLJ46254 fis, clone TESTI4023096, highly similar to Solute carrier family 12 member 6 {ECO:0000313|EMBL:BAG54635.1};+++[H0YKE6_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452771}; Flags: Fragment;+++[H0YKJ2_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452828}; Flags: Fragment;+++[H0YKL8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452857}; Flags: Fragment;+++[H0YKQ8_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000452904};+++[H0YMQ9_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_c {ECO:0000313|EMBL:EAW92298.1}; SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000453702};+++[H0YNJ5_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 member 6 {ECO:0000313|Ensembl:ENSP00000454037}; Flags: Fragment;+++[Q3ZCQ6_HUMAN|Unreviewed]SubName: Full=SLC12A6 protein {ECO:0000313|EMBL:AAH51744.1};+++[Q6NSI7_HUMAN|Unreviewed]SubName: Full=Solute carrier family 12 (Potassium/chloride transporters), member 6 {ECO:0000313|EMBL:AAH70107.2};"]
[9991,"'PTBP3'",424,597,510.5,{"$nulls":4},"GO:0005634///nucleus","GO:0003723///RNA binding+++GO:0003676///nucleic acid binding","GO:0030154///cell differentiation+++GO:0043249///erythrocyte maturation+++GO:0006397///mRNA processing+++GO:0033119///negative regulation of RNA splicing+++GO:0008380///RNA splicing+++GO:0045595///regulation of cell differentiation+++GO:0009653///anatomical structure morphogenesis","IPR034326///ROD1, RNA recognition motif 1+++IPR034798///Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2+++IPR012677///Nucleotide-binding alpha-beta plait domain superfamily+++IPR006536///HnRNP-L/PTB+++IPR033110///ROD1, RNA recognition motif 4+++IPR000504///RNA recognition motif domain+++IPR035979///RNA-binding domain superfamily","[PTBP3_HUMAN|Reviewed]RecName: Full=Polypyrimidine tract-binding protein 3; AltName: Full=Regulator of differentiation 1; Short=Rod1;+++[A0A024R163_HUMAN|Unreviewed]SubName: Full=ROD1 regulator of differentiation 1 (S. pombe), isoform CRA_b {ECO:0000313|EMBL:EAW59101.1};+++[B1ALY4_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000388024}; Flags: Fragment;+++[X6R242_HUMAN|Unreviewed]SubName: Full=Polypyrimidine tract-binding protein 3 {ECO:0000313|Ensembl:ENSP00000210227}; Flags: Fragment;"]
[9992,"'KCNE2'",0,1,0.5,"04971///Gastric acid secretion","H00720///Long QT syndrome+++H00731///Atrial fibrillation",null,null,"GO:0005783///endoplasmic reticulum+++GO:0016020///membrane+++GO:0008076///voltage-gated potassium channel complex+++GO:0009986///cell surface+++GO:0005794///Golgi apparatus+++GO:0016021///integral component of membrane+++GO:0005886///plasma membrane+++GO:0005764///lysosome","GO:0005249///voltage-gated potassium channel activity+++GO:0044325///ion channel binding+++GO:0005267///potassium channel activity+++GO:0042803///protein homodimerization activity+++GO:0005515///protein binding+++GO:0005251///delayed rectifier potassium channel activity+++GO:0005244///voltage-gated ion channel activity+++GO:1902282///voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization+++GO:0015459///potassium channel regulator activity+++GO:0005242///inward rectifier potassium channel activity","GO:0060307///regulation of ventricular cardiac muscle cell membrane repolarization+++GO:1902159///regulation of cyclic nucleotide-gated ion channel activity+++GO:0035690///cellular response to drug+++GO:0006813///potassium ion transport+++GO:1990573///potassium ion import across plasma membrane+++GO:0086009///membrane repolarization+++GO:1901800///positive regulation of proteasomal protein catabolic process+++GO:0086005///ventricular cardiac muscle cell action potential+++GO:0060306///regulation of membrane repolarization+++GO:1903817///negative regulation of voltage-gated potassium channel activity+++GO:1901979///regulation of inward rectifier potassium channel activity+++GO:1901387///positive regulation of voltage-gated calcium channel activity+++GO:0071805///potassium ion transmembrane transport+++GO:0006811///ion transport+++GO:0097623///potassium ion export across plasma membrane+++GO:0034765///regulation of ion transmembrane transport+++GO:0098915///membrane repolarization during ventricular cardiac muscle cell action potential+++GO:0086011///membrane repolarization during action potential+++GO:1902259///regulation of delayed rectifier potassium channel activity+++GO:0043586///tongue development+++GO:1901379///regulation of potassium ion transmembrane transport+++GO:0007568///aging+++GO:1902260///negative regulation of delayed rectifier potassium channel activity+++GO:0086002///cardiac muscle cell action potential involved in contraction+++GO:0086091///regulation of heart rate by cardiac conduction","IPR000369///Potassium channel, voltage-dependent, beta subunit, KCNE+++IPR005425///Potassium channel, voltage-dependent, beta subunit, KCNE2","[KCNE2_HUMAN|Reviewed]RecName: Full=Potassium voltage-gated channel subfamily E member 2; AltName: Full=MinK-related peptide 1; AltName: Full=Minimum potassium ion channel-related peptide 1; AltName: Full=Potassium channel subunit beta MiRP1;+++[Q2N1I3_HUMAN|Unreviewed]SubName: Full=Cardiac voltage-gated potassium channel accessory subunit 2 {ECO:0000313|EMBL:ABB00303.1}; Flags: Fragment;"]
[9993,"'DGCR2'",2953,3287,3120,"04137///Mitophagy - animal+++04140///Autophagy - animal",{"$nulls":3},"GO:0016021///integral component of membrane","GO:0030246///carbohydrate binding","GO:0009887///animal organ morphogenesis+++GO:0050890///cognition+++GO:0007155///cell adhesion","IPR023415///Low-density lipoprotein (LDL) receptor class A, conserved site+++IPR016187///C-type lectin fold+++IPR034010///DGCR2-like, C-type lectin-like domain+++IPR001304///C-type lectin-like+++IPR016186///C-type lectin-like/link domain superfamily+++IPR002172///Low-density lipoprotein (LDL) receptor class A repeat+++IPR036055///LDL receptor-like superfamily+++IPR001007///VWFC domain","[IDD_HUMAN|Reviewed]RecName: Full=Integral membrane protein DGCR2/IDD; Flags: Precursor;+++[B7Z3C4_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2, isoform CRA_c {ECO:0000313|EMBL:EAX03063.1}; SubName: Full=cDNA FLJ50536, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12160.1};+++[B7Z3T5_HUMAN|Unreviewed]SubName: Full=cDNA FLJ50553, highly similar to Integral membrane protein DGCR2/IDD {ECO:0000313|EMBL:BAH12321.1};+++[F6SYP7_HUMAN|Unreviewed]SubName: Full=Integral membrane protein DGCR2/IDD {ECO:0000313|Ensembl:ENSP00000445069};+++[Q5CZ70_HUMAN|Unreviewed]SubName: Full=Uncharacterized protein DKFZp686I1730 {ECO:0000313|EMBL:CAI59783.1};+++[Q8IWC8_HUMAN|Unreviewed]SubName: Full=DiGeorge syndrome critical region gene 2 {ECO:0000313|EMBL:AAH40500.1};"]
[9994,"'CASP8AP2'",75,106,90.5,"04140///Autophagy - animal+++04137///Mitophagy - animal+++03008///Ribosome biogenesis in eukaryotes",{"$nulls":3},"GO:0016605///PML body+++GO:0005739///mitochondrion+++GO:0005737///cytoplasm+++GO:0005654///nucleoplasm+++GO:0005634///nucleus","GO:0042802///identical protein binding+++GO:0003714///transcription corepressor activity+++GO:0032184///SUMO polymer binding+++GO:0003677///DNA binding+++GO:0005515///protein binding+++GO:0008656///cysteine-type endopeptidase activator activity involved in apoptotic process+++GO:0002020///protease binding+++GO:0016505///peptidase activator activity involved in apoptotic process+++GO:0005123///death receptor binding","GO:1903507///negative regulation of nucleic acid-templated transcription+++GO:0097190///apoptotic signaling pathway+++GO:0007165///signal transduction+++GO:0008625///extrinsic apoptotic signaling pathway via death domain receptors+++GO:0036337///Fas signaling pathway+++GO:0006915///apoptotic process+++GO:0071260///cellular response to mechanical stimulus+++GO:0006919///activation of cysteine-type endopeptidase activity involved in apoptotic process+++GO:0007049///cell cycle","IPR039674///CASP8-associated protein 2+++IPR009057///Homeobox-like domain superfamily","[C8AP2_HUMAN|Reviewed]RecName: Full=CASP8-associated protein 2; AltName: Full=FLICE-associated huge protein;+++[A0A087WTW5_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000478179};+++[A0A096LP21_HUMAN|Unreviewed]SubName: Full=CASP8-associated protein 2 {ECO:0000313|Ensembl:ENSP00000485346}; Flags: Fragment;+++[A7E2C0_HUMAN|Unreviewed]SubName: Full=CASP8AP2 protein {ECO:0000313|EMBL:AAI50275.1};+++[L8EC81_HUMAN|Unreviewed]SubName: Full=Alternative protein CASP8AP2 {ECO:0000313|EMBL:CCQ43107.1};"]
[9997,"'SCO2'",271.88,204.83,238.355,null,"H01200///Fatal infantile cardioencephalomyopathy+++H02041///Myopia+++H01368///Cytochrome c oxidase (COX) deficiency",null,null,"GO:0005759///mitochondrial matrix+++GO:0030016///myofibril+++GO:0016021///integral component of membrane+++GO:0031305///integral component of mitochondrial inner membrane+++GO:0005739///mitochondrion+++GO:0016020///membrane+++GO:0005743///mitochondrial inner membrane","GO:0005507///copper ion binding+++GO:0046872///metal ion binding+++GO:0005515///protein binding+++GO:0016763///transferase activity, transferring pentosyl groups+++GO:0004645///phosphorylase activity+++GO:0015035///protein disulfide oxidoreductase activity","GO:0045454///cell redox homeostasis+++GO:0033617///mitochondrial respiratory chain complex IV assembly+++GO:0006206///pyrimidine nucleobase metabolic process+++GO:0006878///cellular copper ion homeostasis+++GO:0001654///eye development+++GO:0006825///copper ion transport+++GO:0055114///oxidation-reduction process+++GO:0006213///pyrimidine nucleoside metabolic process+++GO:0008535///respiratory chain complex IV assembly","IPR000312///Glycosyl transferase, family 3+++IPR017276///Synthesis of cytochrome c oxidase, Sco1/Sco2+++IPR013766///Thioredoxin domain+++IPR036249///Thioredoxin-like superfamily+++IPR035902///Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily+++IPR017872///Pyrimidine-nucleoside phosphorylase, conserved site+++IPR013102///Pyrimidine nucleoside phosphorylase, C-terminal+++IPR000053///Thymidine/pyrimidine-nucleoside phosphorylase+++IPR018090///Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic+++IPR003782///Copper chaperone SCO1/SenC+++IPR036566///Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily+++IPR017459///Glycosyl transferase family 3, N-terminal domain+++IPR036320///Glycosyl transferase family 3, N-terminal domain superfamily","[SCO2_HUMAN|Reviewed]RecName: Full=Protein SCO2 homolog, mitochondrial; Flags: Precursor;+++[A0A1W2PP80_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491034}; Flags: Fragment;+++[A0A1W2PQK0_HUMAN|Unreviewed]SubName: Full=Protein SCO2 homolog, mitochondrial {ECO:0000313|Ensembl:ENSP00000491753}; Flags: Fragment;"]